bluuebunny/crossref_metadata_2025 huggingface dataset:
Mobilidade acadêmica e internacionalização
Authors: Gomides Paula Aparecida Diniz , Macedo Maria do Socorro Alencar Nunes , Almeida Grazielly Aparecida de
Published: January 2024

Introdução: Analisamos o Programa de Tutoria Social Voluntária desenvolvido na Universidade Federal de São João del Rei (UFSJ), entendendo-o como uma ação que visa estimular a Internacionalização em Casa na instituição. De forma semestral, estudantes brasileiros são selecionados via edital pela Assessoria Internacional (ASSIN), para acompanharem alunos estrangeiros em situação de mobilidade. Essa seleção ocorre desde 2017 e tem proporcionado intercâmbios culturais entre os estudantes, além de contribuir para que brasileiros e estrangeiros aprendam mais sobre a cultura e a história de nosso país. Objetivo: A partir do exposto, buscamos compreender como o Programa é organizado e quais as ações nas quais estudantes brasileiros e estrangeiros estão envolvidos. Metodologia: Acompanhamos algumas das atividades culturais organizadas pela ASSIN, entre 2017 e 2018, entrevistamos representantes do órgão, analisamos os documentos que norteiam a internacionalização na instituição e os editais de seleção do Programa, bem como alocamos a ação em um cenário de esforço nacional que visa o intercâmbio cultural entre brasileiros e estrangeiros. Resultados/Conclusão: Nossas considerações acerca desta política ressaltam a importância das atividades de tutoria, sobretudo em um contexto de corte de verbas para a promoção da mobilidade de brasileiros, podendo constituir um forte alicerce para práticas de internacionalização ativa no país.
Speedy Recovery of Subcutaneous Abscess and The Presence of Overgrown Nails in A Pygmy Hedgehog: A Case Report
Authors: Budiono Novericko Ginger , Wen Nicole Ting Qian , Rajendran Punithe Raj A/L , Proboningrat Annise
Published: January 2024

This study reported that a 15-month-old intact female African pygmy hedgehog (Atelerix albiventris) was presented to IPB University Veterinary Teaching Hospital to evaluate a 1.5 cm × 1.5 cm × 0.5 cm mass on the left ventral thorax, three days after the mass was first discovered by the owner. Overgrown nails were observed on all four toes of each of the four limbs of the hedgehog. The body weight was 150 g, and the axial temperature was 36.5°C. The heart and respiratory rates were 180 per minute and 40 per minute, respectively. After a thorough physical examination, the patient was diagnosed with subcutaneous abscesses and overgrown nails. The abscess was surgically resected using a local anesthetic. The overgrown nails were trimmed to prevent further injury and the recurrence of abscesses. Following surgery, the hedgehog was discharged directly from the hospital and treated using Amoxicillin 15 mg/kg per oral every 12 hours for seven days, daily routine wound cleaning with sodium chloride, and topical powder of neomycin sulfate 5 mg/g and bacitracin 250 IU/g. The patient responded effectively to the systemic treatment, and medical signs and symptoms resolved. The hedgehog fully recovered from the subcutaneous abscess 14 days after the first hospital visit. No recurrence was reported in the subsequent month after resolution.
Comparison of Corticomedullary Ratio and Medullary Rim Sign in Feline Lower Urinary Tract Disease Recurrence in Persian Breed
Authors: Wardhana Analis Wisnu , Jihan Putri , Suwardani Gagas Wiratama
Published: January 2024

The Persian cat breed has grown rapidly in the last decade. This increase is not balanced with adequate maintenance, especially related to feed management and this causes problems, one of which is the emergence of feline lower urinary tract disease (FLUTD). Several complications often occur in cases of FLUTD recurrence, one of which is the kidneys. This study aimed to determine the differences in the corticomedullary ratio (CMR) and medullary rim sign (MRS) using an ultrasonography (USG) in Persian cats with FLUTD recurrences. Kidney examination was carried out using a linear USG probe with a frequency of 10MHz, with a dorsal view of the kidney. The parameters were analyzed using the independent t-test. Based on the calculation results, it was found that there were no significant differences in CM and MRS values in cats with FLUTD and FLUTD recurrences. These results indicated that cats with FLUTD recurrences have slightly disorders in kidney tissue but it still did not affect the macro anatomy of the kidney, and might cause chronic kidney disease.
Essential Oil of Patchouli Inhalation Exhibits An Anxiolytic-Like Effect in Mice: Elevated Plus-Maze Test
Authors: Johansyah Fadilla Anita Kinksky , Hestianah Eka Pramyrtha , Rimayanti Rimayanti , Hidajati Nove , Santoso Kuncoro Puguh , Sudjarwo Sri Agus , Hidayatik Nanik
Published: January 2024

Anxiety disorder is one of the important public health problems. This study aimed to find out whether patchouli (Pogostemon cablin (Blanco) Benth.) essential oil (PEO) has an anxiolytic-like effect in mice. A total of 20 mice were divided into five treatment groups i.e. (C1) was treated with 1 mg/kg of saline intraperitoneally; (C2) was treated with 1 mg/kg of diazepam intraperitoneally; (T1) 1% PEO inhalation, (T2) 2.5% PEO inhalation, and (T3) 5% PEO inhalation. All experimental animals were put in the Elevated Plus-Maze (EPM), observed for five minutes, and investigated the following parameters i.e. the total number of squares that are transverse in the open arms (STO), the number of visits to the open arms (VOA), the number of visits to the closed arms (VCA), the time spent in the open arms (TOA), and the time spent in the closed arms (TCA). In results, T1 and T2 groups had a minor impact on the VOA. T1 group also had little effect on TOA. Closed-arm activities (VCA and TCA) were unaffected by any of the treatments. The conclusion was revealed that T1 or less of PEO inhalation can potentially provide anxiolytic-like effects in mice.
Hematological Profile in Dairy Cattle with Foot and Mouth Diseases in Lembang, West Bandung
Authors: Majid Rully Abiyoga , Septiyani Septiyani , Gradia Resti , Rosdianto Aziiz Mardanarian , Hidayatik Nanik
Published: January 2024

Foot and mouth disease (FMD) is a widespread infectious disease that significantly affects the dairy farming sector in Indonesia. In reducing the impact caused by FMD, proper treatment performed by veterinarians is necessary. Hematological profile can be used as a data reference to prioritize dairy cattle infected with FMD. This study aimed to describe the hematological profile in dairy cattle with FMD infection. This study was collected data from 15 dairy cattle with FMD infection at Koperasi Peternak Sapi Bandung Utara (KPSBU), Lembang, West Bandung, West Java, Indonesia. Parameters observed in the hematology analyzer were the numbers of erythrocytes, leukocytes, lymphocytes, neutrophils, platelets, hemoglobin, hematocrit, MCV, MCH, MCHC, RDW, and MPV. The results of the examination of hematological profile showed various numbers. It found lymphopenia, neutrophilia, and high MPV values. It was suggested for veterinarians to refer to this study's results to determine an effective and efficient treatment.
Diluent and Storage Time Effect on Sperm Abnormality and MDA Level in Muscovy Duck Semen at 27oC
Authors: Andaruisworo Sapta , Tanjungsari Ardina , Yuniati Erna , Khairullah Aswin Rafif
Published: January 2024

This study aimed to determine sperm abnormality and MDA level in Muscovy duck semen in different dilution and storage at 27oC. This study was used in the level of dilution of glutinous semen with a long time store differently at 27oC. In this study, the parameters of the mass motility of spermatozoa were used individual motility, spermatozoa abnormalities, and activity test. A Muscovy duck, healthy and have a high libido were used then divided into treatment groups i.e. (A0) 0; (A1) 5 times; (A2) 10 times; and (A3) 15 times, the second factor as a subplot was the storage time (BO) 0; (B1) 60 minutes; (B2) 120 minutes; and (B3) 180 minutes stored at 27oC with 3 replications. In results, this study was reported abnormalities at a dilution rate in A1 group of 5 times with a shelf life in B1 group of 60 minutes and in B2 group of 120 minutes.
Az egészségmagatartás tényezőinek változása a COVID-19 hatására
Authors: Pfau Christa , Kanyó Krisztina Zsófia
Published: January 2024

The coronavirus pandemic caused profound changes in many aspects of people's lives, especially in the area of health behaviour. The restrictions caused by the pandemic have had negative effects on both the physical and mental health of society, while also transforming the way individuals exercise. The aim of our research was to analyse the changes in health behaviour of Hungarian adults, including their sporting habits as well as their mental health, caused by the COVID-19 pandemic. We also focused on comparing the experiences of a population that regularly participates in sport and a population that rarely or never participates in sport. Results of the survey showed that individuals who regularly participate in sport activities rated their general physical health significantly better than those living a more sedentary life. More than half of the sample stated that they did not experience any particular change in their physical health, but the second highest percentage of respondents reported that their health had been affected negatively by the pandemic period. Results also showed that almost half of respondents said that their sporting habits had not changed as a result of the pandemic, while many reported that their sporting frequency had decreased. Finally, we also analysed the changes in sporting habits with regard to the place of residence, finding that those individuals living in an apartment complex building were most likely to choose a different type of exercise from the one they had previously practised, while a higher proportion of individuals living in a suburban area, or with access to garden reported that they had started to doing sports.Our research provided partial confirmation that the pandemic had a negative effect  on people's health behaviour, but given the high levels of exercise in the target group,it is not surprising that many did not experience any change in sporting habits or physical health. 
JEL Code: I12
Evaluation of the Quality and Reliability of YouTube Videos on Polymyalgia Rheumatica
Authors: YETİŞİR Ayşegül , SARIYILDIZ Aylin
Published: January 2024

To investigate polymyalgia rheumatica (PMR)-related YouTube videos’ quality and reliability. We searched the term “polymyalgia rheumatica” on https://www.youtube.com. The most viewed 60 YouTube videos about PMR were analyzed by two independent physiatrists. Study data used in the analysis included upload date, total views, number of likes and comments, length of video, contents of video, source of the uploader, and targeted population. The Global Quality Scale (GQS) and the Modified DISCERN tool were used to assess PMR-related video quality and reliability, respectively. Comparative analyses of video features, quality, and reliability were performed based on source of uploaders (professional and non-professional) and GQS score subgroups. Of the videos analyzed, 76.7% and 61.7% of the uploaded videos were related to symptoms and treatment, respectively, and 65% of the videos were uploaded by healthcare professionals. The median GQS and modified DISCERN tool scores were 3 in professionals and 2 in non-professionals (p< 0.001 and p = 0.001, respectively). According to the GQS score, there was no significant difference in terms of total views, number of likes, number of comments, and view ratio values between low, moderate, and high quality videos. 35% of the YouTube videos concerning PMR were uploaded by non-professionals with poor reliability and quality. Therefore, healthcare professionals need to produce videos that provide more accurate and high quality information about PMR on this platform. Before being published, YouTube videos should be evaluated objectively for the accurity of their content.
Printing surface cuprous oxides featured liquid metal for non-enzymatic electrochemical glucose sensor
Authors: Luo Yiyao , Liao Gengcheng , Guo Zixuan , Huang Zongyu , Ren Long , Qi Xiang
Published: January 2024

Electrochemical glucose sensors that rely on two-dimensional (2D) oxides have attracted significant attention owing to the strong sensing activity of 2D oxides, but their practical application is hindered by the complexity and high cost of fabrication of electrodes and integrated devices. Herein, a convenient and effective fabrication route that includes printing a Ga-based liquid metal (LM) as a current collection electrode, followed by growing electrochemically active 2D oxides directly on the surface of Ga-based LMs under mild conditions, is developed for non-enzyme-based electrochemical sensors. Specifically, 2D annealed Cu-Oxide (ACO) is successfully grown on a printed Ga electrode through a galvanic replacement reaction, resulting in the formation of a mechanically and electrically well-matched interface between the active sensing materials and the current collection substrate. Benefitting from the high quantity of 2D ACO and good charge transfer at the interface, the as-prepared ACO electrode exhibits attractive glucose sensing performance, with a wide linear range (1 μM-10 mM) of effective detection, low detection limit down to 1 μM, and high sensitivity of 0.87 μA·mM-1·cm-2. Our study highlights the potential of using LMs in bio-sensing applications and provides a non-enzyme-based electrochemical biosensor platform for effective glucose detection in diets and clinical diagnostic settings.
PENGEMBANGAN LEMBAR KERJA PESERTA DIDIK (LKPD) PADA MATERI POLA BILANGAN BERBASIS MASALAH KONTEKSTUAL BUDAYA BANJAR KELAS VIII SMP/MTS
Authors: Hariyadi Novia Salsabila , Zulkarnain Iskandar , Amalia Rizki
Published: January 2024

Kurangnya ketersediaan bahan ajar matematika di sekolah yang mengaitkan dengan masalah kontekstual membuat para peserta didik kesulitan dalam memahami konsep suatu materi. Bahan ajar berupa LKPD yang digunakan juga tidak terdapat satupun yang mengaitkan materi dengan kebudayaan Banjar. Salah satu solusi untuk meningkatkan pemahaman konsep matematika adalah dengan menyediakan bahan ajar berupa Lembar Kerja Peserta Didik (LKPD) berbasis masalah kontekstual budaya Banjar. Penelitian ini bertujuan untuk menghasilkan LKPD pada materi pola bilangan berbasis masalah kontekstual budaya Banjar kelas VIII SMP/MTs yang valid, praktis, dan efektif. Penelitian ini menggunakan metode penelitian pengembangan model Plomp yang terdiri dari empat tahap, yaitu investigasi awal, desain, realisasi/konstruksi, serta  tes, evaluasi, dan revisi. Uji coba dilakukan kepada 31 peserta didik kelas VIII E SMPN 24 Banjarmasin. Teknik pengumpulan data menggunakan instrumen validasi ahli, angket respon peserta didik, dan tes hasil belajar. Berdasarkan uji validitas oleh dua validator diperoleh rerata sebesar 3,22 dengan kriteria valid. Berdasarkan angket respon peserta didik diperoleh 3,32 dengan kriteria praktis. Berdasarkan tes hasil belajar diperoleh lebih dari 80% peserta didik mencapai nilai lebih dari sama dengan 75 sehingga dinyatakan efektif. Dengan demikian, dihasilkan LKPD pada materi pola bilangan berbasis masalah kontekstual budaya Banjar kelas VIII SMP/MTs yang valid, praktis, dan efektif.
PENGEMBANGAN SOAL KONTEKSTUAL BERBASIS KEARIFAN LOKAL PADA PEMBELAJARAN MATEMATIKA SMA/MA
Authors: Basriannor Agus , Zulkarnain Iskandar , Hidayanto Taufiq
Published: January 2024

Matematika merupakan salah satu ilmu yang penting dalam kehidupan bahkan dalam perkembangan ilmu pengetahuan dan teknologi. Namun masih ada siswa yang mengalami kesulitan dalam memahami soal matematika. Hal tersebut karena soal yang diajukan terkesan membosankan dan terfokus pada masalah yang sulit dibayangkan oleh siswa. Oleh sebab itu, hendaknya siswa diberikan soal yang berhubungan dengan kehidupan  secara nyata atau kontekstual. Tujuan penelitian ini adalah menghasilkan soal kontekstual berbasis kearifan lokal pada pembelajaran matematika SMA/MA yang valid dan praktis. Penelitian menggunakan metode penelitian dan pengembangan (Research and Development) dengan model pengembangan Tessmer tipe formative research mencakup tahap preliminary dan tahap formative evaluation yang terdiri dari self evaluation, expert reviews, one-to-one, small group, dan field test. Namun, pada penelitian ini hanya sampai pada small group. Pada penelitian ini pengumpulan data menggunakan istrumen validasi ahli dan angket respon siswa. Berdasarkan hasil analisis uji validitas yang diisi oleh tiga orang validator menghasilkan rata-rata skor 3,62 yang berada pada kategori valid. Kemudian, berdasarkan hasil analisis uji angket respon siswa menghasilkan rata-rata skor 3,32 yang menunjukkan bahwa soal berada pada kategori praktis. Dengan demikian, soal kontekstual berbasis kearifan lokal pada pembelajaran matematika SMA/MA memenuhi kriteria valid dan praktis.
PENGEMBANGAN TES FORMATIF MATEMATIKA MATERI BILANGAN BULAT BERBASIS HIGHER ORDER THINKING SKILLS (HOTS) UNTUK SISWA SMP
Authors: Yuwin Utami Cinta Bella , Pasani Chairil Faif , Suryaningsih Yuni
Published: January 2024

Salah satu kemampuan yang termuat pada Kurikulum 2013 adalah kemampuan berpikir tingkat tinggi. Namun, pada kenyataannya pada buku mata pelajaran matematika terdapat soal-soal HOTS berlevel rendah. Kemampuan berpikir siswa Indonesia masih rendah dikarenakan kurang terlatih dalam menyelesaikan soal HOTS berdasarkan survei TIMSS. Selain itu, guru belum mengembangkan soal HOTS dan tes formatif yang didesain untuk melatih kemampuan HOTS siswa belum tersedia. Tujuan penelitian pengembangan ini adalah menghasilkan tes formatif matematika materi bilangan bulat berbasis HOTS untuk siswa SMP kelas VII yang valid. Model pengembangan formatif research oleh Tessmer menjadi model pengembangan dalam penelitian. Tahapan yang dilakukan yaitu preliminary, self evaluation, dan expert reviews. Validasi dilakukan oleh empat orang ahli. Sebelas butir soal tes formatif berbasis HOTS berbentuk pilihan ganda adalah hasil penelitian ini. Berdasarkan kevalidan tes formatif diperoleh skor rata-rata sebesar 2,83 dari segi materi, kontstruksi, dan bahasa. Dengan demikian, kriteria kevalidan tes formatif matematika materi bilangan bulat berbasis HOTS untuk siswa SMP kelas VII dikatakan valid.
Comparison of Bronsted and Lewis Acid Catalyzed Conversion of CBD Into Other Cannabinoids
Authors: Buijs Wim
Published: January 2024

There is a continuous interest in cannabinoids like Δ9-tetrahydro cannabinol (Δ9-THC) and cannabidiol (CBD). A patent of Webster et al., described the conversion of CBD to either D8-THC or D9-THC, depending on the acid catalyst applied. The use of para-toluene sulfonic acid (pTSA) led to the formation of D8-THC, while boron trifluoride etherate (BF3·Et2O) yielded mainly D9-THC. The enormous difference in product selectivity between these two catalysts was investigated with Molecular Modeling. It was found that pTSA leads to fast isomerization of Δ9-CBD to Δ8-CBD and subsequent ring closure to Δ8-THC. BF3·Et2O catalysis leads to the formation of tertiary carbenium ions in the Transition States which yield D9-THC and some iso D8-THC. Under dry conditions in refluxing toluene, it was found that pTSA is predominantly present as a dimer, and only a small fraction is available as monomeric catalyst. Applying the computationally derived activation barriers in Transition State theory yielded reaction rates predicting amounts of cannabinoids that are in close agreement with the experimental findings.
Cambodian Green Economy Transition: Background and SWOT Analysis
Authors: Chan Puthearath
Published: January 2024

This research aims to understand the Cambodian green economy transition and analyze its strengths, weaknesses, opportunities, and threats (SWOT). The research showed that Cambodia has been significantly transitioning its green economy since 2009 as evidenced by the National Green Growth Roadmap. Cambodia also established the National Council for Green Growth in 2012 and upgraded it to the National Council for Sustainable Development in 2015 in alignment with 2030 Agenda for Sustainable Development of the United Nations. The members of the Council are from all the government’s ministries and relevant inter-ministerial councils/committees, which are significant for policymaking. All governors of the capital and provincial administrations are also its members, which are significant for supporting and implementing the works at the subnational levels. Under the structure of the Council’s Secretariat, Department of Green Economy is playing an important role in promoting green economic development in Cambodia by looking at national policies and strategic plans, undertaking projects, and mobilizing resources. Through coordination between this Department and UNIDO, Cambodia in 2022 became a Member of the United Nations Partnership for Action on Green Economy. The findings showed that Cambodia is transitioning its green economy at the right time, especially the new government’s Pentagonal Strategy strongly supported this green economy transition with a clear and strong political commitment. The national inter-ministerial council for sustainable development is also very significant for cross sectoral policy-making and implementing levels, inclusively for promoting green economic development.
Smart Contract Vulnerability Detection based on Multi-scale Encoders
Authors: Guo Junjun , Lu Long , Li Jingkui
Published: January 2024

Vulnerabilities in smart contracts may trigger serious security events, and the detection of smart contract vulnerabilities has become a significant problem. In this paper, by using the multi-scale cascade encoder architecture as the backbone, we propose a novel Multi-scale Encoder Vulnerability Detection (MEVD) approach to detect well-known high-risk vulnerabilities in smart contracts. Firstly, we use the gating mechanism to design a unique Surface Feature Encoder (SFE) to enrich the semantic information of code features. Then, by combining a Base Transformer Encoder (BTE) and a Detail CNN Encoder (DCE), we introduce a dual-branch encoder to capture the global structure and local detail features of the smart contract code, respectively. Finally, to focus the model's attention on vulnerability-related characteristics, we employ the Deep Residual Shrinkage Network (DRSN). Experimental results on three types of high-risk vulnerability datasets demonstrate performance compared to state-of-the-art methods, and our method achieves an average detection accuracy of 90%.
Heading for the Frontline: Nursing Graduates Entering the Profession During a Global Pandemic.
Authors: Terry Victoria R. , Parsons-Smith Renee L. , Elliott Jessica , Roderick Geraldine , Luyke Patricia , Terry Peter C.
Published: January 2024

COVID-19 affected health and wellbeing globally. Graduating nursing students face a variety of stressors and entering the nursing profession during the pandemic added additional stress. Mood, perceived stress, resilience, and coping were assessed in an Australian sample of 112 graduating nursing students, who completed the Brunel Mood Scale (BRUMS), Perceived Stress Scale (PSS-4), and Brief Resilient Coping Scale (BRCS). Mean BRUMS scores for tension, fatigue, and confusion were significantly above population norms, and vigour scores significantly below. Mean PSS-4 scores were reflective of population norms, but showed higher levels of stress for younger and on-campus students compared to those who were older or who studied externally. BRCS data showed that 82.1% of the graduating nursing students were medium or high resilient copers. Mood profiles suggested that 19.6% of participants had elevated mental health risk, 23.2% showed potential risk of burnout, and only 17.9% reported mood profiles associated with positive mental health. High mean tension scores reported by the graduating nursing students indicated apprehension about joining the profession, although stress, resilience and coping scores suggested they were adequately managing the additional stressors generated by a global pandemic.
Experimental Studies and Analytical Approaches on Non-limited Earth Pressures of Soilbag Reinforced Retaining Structures with Surcharge Loads
Authors: Bian Changrong , Liu Ruonan , Lai Zhiqiang , Wang Zhongmei , Fan Kewei
Published: January 2024

The earth pressure acting on soilbag reinforced retaining structures subjected to surcharge loads under non-limited states, is crucial for designing these structures. In this study, the earth pressures are investigated through model tests of the soilbag reinforced retaining wall. Findings from these tests reveal a non-linear distribution of lateral earth pressure on the wall when subjected to surcharge loads in non-limited states, with an observed escalation in pressure corresponding to increased surcharge loads. Compression tests on soilbags were conducted to analyze their lateral stress-strain behavior. Insights from these tests facilitated the development of a predictive method for estimating lateral pressure on soilbag reinforced retaining walls under similar conditions. This method, rooted in the principle of force equilibrium in differential elements, has its accuracy and reliability substantiated by the alignment of its predictions with the model test outcomes.
Comparative Analysis of Strap-Induced Pressure at the Toe Hold Area: Assessing the Impact of Rolled Inner Seam Flip Flops in Healthy Volunteers
Authors: Rao Shreya , Maibach Howard
Published: January 2024

Abstract:Background: Foot ulcers, especially dorsal foot ulcers caused by straps in footwear, can lead to discomfort, pain, and severe complications, particularly in individuals with diabetes and leprosy. While plantar foot pressure measurements have been extensively studied, research on the impact of strap-induced pressure on the dorsal foot aspect remains limited.Research question: The main research question of this prospective study is: Does the implementation of a rolled inner seam strap design (RIS) in flip-flops result in reduced pressure at the toehold area compared to traditional strap designs (Control) in healthy volunteers?Methods: We studied healthy female volunteers, with 10 feet (5 left and 5 right) per arm of the study. Two types of flip-flops, RIS and Control, were compared in a standardized 5-step walk trial on a hardwood floor. Pressure at the toehold was measured using Pressure Sensitive Switches with portable, accurate, ultra-thin pressure sensors. Paired t-tests compared the maximum pressure at the toehold between RIS and Control flip-flops (p < 0.05).Results: The study revealed a statistically significant difference in pressure at the toehold between the RIS and Control flip-flops (p = 0.0014). The mean difference of -40.90 grams (95% CI: -61.22 to -20.58) indicated that the RIS exerted significantly lower pressure than the Control flip flops. The RIS group had a mean pressure of 29.30 grams. The Control group had a mean pressure of 70.20 grams at the toehold area.Significance: The findings of this study have significant clinical implications for individuals at risk of foot ulcers, particularly those with neuropathic conditions such as diabetes and leprosy. The implementation of the RIS design in flip-flops may offer a practical and cost-effective solution to reduce strap-induced pressure and mitigate the risk of strap-related foot ulcers, especially in resource-limited settings where comprehensive foot care is lacking.
Rectangular Natural Feature Recognition and Pose Measurement Method for Non-Cooperative Spacecraft
Authors: Wang Fengxu , Xu Wenfu , Yan Lei , Xie Chengqing , Pu Weihua
Published: January 2024

Accurately estimating the pose of spacecraft is indispensable for space applications. However, such targets are generally non-cooperative, i.e., no markers are mounted on it and no parts for operation. Therefore, the detection and measurement of a non-cooperative target is very challenging. Stereovision sensors are important solutions in the near field. In this paper, a rectangular natural feature recognition and pose measurement method for non-cooperative spacecraft is proposed. Solar panels or the bodies of spacecraft are selected as detection objects and their image features are captured by stereo vision. These rectangle features are then reconstructed in 3D Cartesian space through parallelogram fitting on the image planes of two cameras. The vertexes are used to calculate the center position of the rectangle and the direction of the fixed coordinate system to solve the pose and attitude of the non-cooperative target. An experimental system is built to validate the effectiveness of the algorithm. The experimental results show that the average position measurement error of the algorithm is about 10mm and the average attitude measurement error is less than 1°. The results show that the proposed method has high accuracy and efficiency.
Spectral-Spatial Feature Fusion for Hyperspectral Anomaly Detection
Authors: Liu Shaocong , Li Zhen , Wang Guangyuan , Qiu Xianfei , Liu Tinghao , Cao Jing , Zhang Donghui
Published: January 2024

Hyperspectral anomaly detection is to recognize anomalies from complex scene in an unsupervised way. Currently, many spectral-spatial detection methods have been proposed with a cascaded manner. However, they often neglect complementary characteristics between spectral and spatial dimensions, which easily leads to yield high false alarm rate. To alleviate this issue, a spectral-spatial information fusion (SSIF) method is designed for hyperspectral anomaly detection. First, an isolation forest is exploited to obtain spectral anomaly map, in which the object-level feature is constructed with entropy rate segmentation algorithm. Then, a local spatial saliency detection scheme is proposed to produce spatial anomaly result. Finally, the spectral and spatial anomaly scores are integrated together followed by a domain transform recursive filtering to generate the final detection result. Experiments on five hyperspectral datasets prove that the proposed SSIF produces superior detection result over other state-of-the-art detection techniques.
The Lac Fallère Area as an Example of the Interplay between Deep-Seated Gravitational Slope Deformation and Glacial Shaping (Aosta Valley, NW Italy)
Authors: Dolce Stefano , Forno Maria Gabriella , Gattiglio Marco , Gianotti Franco
Published: January 2024

The Lac Fallère area, located in the upper Clusellaz Valley (tributary of the middle Aosta Valley), is shaped in micaschist and gneiss referred to as the Mont Fort Unit (Middle Penninic) near the tectonic contact with calcschist and marble of the Aouilletta Unit (Combin Zone).
Lac Fallère exibits an elongated shape and is hosted in a WSW–ENE trending depression, according to slope direction. This lake also shows a semi-submerged WSW–ENE rocky ridge, that longitudinally divides the lake. This evidence, in addition to the extremely fractured rocks, indicates the presence of a wide deep-seated gravitational slope deformation (DSGSD), even if this area is not yet included within the regional landslide inventory of the Aosta Valley Region. The Lac Fallère area also shows reliefs involved by glacial erosion (roche moutonnée), a wide cover of subglacial sediments and many moraines essentially referred to as Lateglacial. The DSGSD evolution in a glacial environment produced, as observed in other areas, significant effects both on the facies of Quaternary sediments and the formation of numerous and wide moraines.
Glacial slope sectors and lateral moraines displaced by minor scarps and counterscarps and glaciers using trenches forming several arched moraines suggest an interplay between glacial and gravitational processes, which shared part of their evolution history.
NRF1 or NRF2: Emerging Role of Redox Homeostasis on PERK/NRF/Autophagy Mediated Antioxidant in Tumor and Patient Dependent Chemo Sensitivity
Authors: Dastghaib Sanaz , Shafiee Seyed Mohammad , Ramezani Fatemeh , Ashtari Niloufar , Tabasi Farhad , Saffari-Chaleshtori Javad , Vakili Omid , Siri Morvarid , Igder Somayeh , Zamani Mojdeh , Moballegh Nasery Mahshid , Kokabi Fariba , Wiechec Emilia , Mostafavi-Pour Zohreh , Mokarram Pooneh , Ghavami Saeid
Published: January 2024

Chemo-resistance is a substantial challenge in the realm of cancer treatment that requires exploring new therapeutic approaches for effective mitigation. Achieving this goal requires examination of the molecular mechanisms involved in both tumor growth and therapeutic interventions. The potential of NRF2 (Nuclear factor E2-related factor 2) in addressing resistance to chemotherapy across diverse cancer types highlights its value as a promising therapeutic approach based on cancer characteristics. Manipulating the NRF2 signaling pathway has a dual impact, offering promise for both preventing and treating cancer, as well as inhibiting carcinogenesis. The influence of the NRF2/KEAP1 pathway on the progression of tumor formation and resistance to drugs has been well-documented. The interplay between the NRF2 signaling pathway and processes such as endoplasmic reticulum (ER) stress, unfolded protein response (UPR), and autophagy plays a crucial protective role. A deeper understanding of NRF2's role in the modulating these pathways is necessary to develop novel approaches for improving chemotherapeutic efficacy. This article discusses the significance of the NRF2-KEAP1 pathway in preventing/promoting cancer and resistance mechanisms to various chemotherapeutic agents, with a focus on the complementary effects of antioxidants via NRF2-mediated signaling pathways. This study aims to provide a molecular basis for targeting NRF2 via inhibitors/activators as promising therapeutic strategies to overcome chemo-resistance.
Bio–Inspired Space Robotics
Authors: Sands Timothy
Published: January 2024

Controlling robots in space with necessarily low material and structural stiffness is quite challenging at least in part due to the resulting very low structural resonant frequencies. The frequencies are sometimes so low, the vary act of controlling the robot with medium or high bandwidth controllers lead to excitation of resonant vibrations. Biomimetics or biomimicry emulates models, systems, and elements of nature for solving such complex problems. Recent seminal publications have re-introduced the viability of optimal command shaping, and one recent instantiation mimics baseball pitching to propose control of highly flexible space robots. The readership will find a perhaps dizzying array of thirteen decently performing alternatives in the literature but could be left bereft selecting a method(s) deemed to be best suited for a particular application. Bio–inspired control of space robotics is presented in a quite substantial (perhaps not comprehensive) comparison, and the conclusions of the study indicate the top three performing methods based on minimizing control effort (i.e., fuel) usage, tracking error mean, and tracking error deviation include.
On the Influence of Climate Change on Hail Risk in Spanish Crop Insurance
Authors: --- Nan Zhou , VILAR-ZANON JOSE L.
Published: January 2024

There is a growing concern about climate change being a serious threat to insurance business sustainability. Knowing if climate warming is a cause for claims and losses increase, and how this cause-effect relationship will develop in the future are two open major questions. In this article, we answer both questions by particularizing the geographical area of Spain, and a precise risk, hailstorm in crop insurance in the line of business of wine grapes. We measure climate change thanks to the Spanish Actuarial Climate Index (SACI). We use a database containing all the claims caused by hail risk in Spain from 1990 to 2022. With homogenized data, we consider as dependent variables the monthly number of claims, monthly number of loss costs equal to one, and monthly total losses. The independent variable is the monthly Spanish Actuarial Climate Index (SACI). We try to explain the former through the latter using regression and quantile regression models. Our main finding is that climate change as measured by SACI explains these three dependent variables. We also give an estimation of the increase of the monthly total losses Value at Risk, corresponding to a future increase in climate change measured in units of SACI. Spanish crop insurance managers should carefully incorporate these conclusions into their decision-making process to keep this line of business sustainable in the future.
Different Carapace Asymmetry among Sexes in Wild Red-Footed Tortoise Chelonoidis carbonarius Spix 1824 (Testudines: Testudinidae)
Authors: Parés-Casanova Pere M. , Salamanca-Carreño Arcesio , Brando P. , Caviedes D.
Published: January 2024

Developmental stability (DS) is indicated by the ability of individuals to resist random environmental and/or genetic perturbations during their development. Fluctuating Asymmetry (FA) is the commonest mean of assessing DS in bilateral traits. FA is defined as small random deviations from an ideal morphological symmetry. To date, little attention has been paid to sexual differences in FA among tortoises. With this issue in mind, we assessed levels of carapace scutation symmetries in a sample of 45 wild adult red-footed tortoise, Chelonoidis carbonarius (13 males and 32 females) from Arauca plains, East Colombia. Procrustes ANOVA reflected statistically significative sex-related FA, with males tending to exhibit a more pronounced asymmetry. Although we cannot identify the potential sources responsible for detected developmental instability, our results suggest a high degree of stress and highlight that human intervention in Arauca are affecting wildlife. Similar studies in the future, correlated with an estimate of human impact, could provide irrefutable proof of causality between FA and environmental stressors. The results of this study can represent an estimate of the fitness status of the studied population at present.
Incidence and Nature of Adverse Events Following COVID-19 Second Boosters: Insights from Taiwan's Universal Vaccination Strategy
Authors: Lin Ching-Hao , Chen Tsung-An , Chiang Pin-Hsuan , Hsieh Ai-Ru , Wu Bih-Ju , Chen Po-Yu , Lin Kuan-Chen , Tsai Zih-Syun , Lin Ming-Hwai , Chen Tzeng-Ji , Chen Yu-Chun
Published: January 2024

This study evaluates the incidence and characteristics of adverse events (AEs) following the second COVID-19 booster dose, leveraging Taiwan's distinctive approach of extending booster vaccinations to all citizens, unlike the targeted high-risk group strategies in other countries. Utilizing data from Taipei Veterans General Hospital's Vaccine Adverse Event Reporting System (VAERS) from October 27, 2022, to January 19, 2023, the research examines AEs in 441 out of 1711 second booster recipients, considering factors like age, vaccine brands, and booster combinations. The findings reveal incidence rates (IR) of 25.6% (95% CI: 21.1-30.8) after the first booster and 24.9% (95% CI: 20.5-30.0) after the second, mostly non-serious, with those having AEs post-first booster 5 times more likely to report them again (Incidence rat rato, 5.02, P<0.001). Significantly, switching from the mRNA1273 vaccine to another brand reduced AE risk by 18%. The study underscores that AEs are more repetitive than cumulative with additional booster doses, advocating for personalized vaccination strategies based on individual medical histories and previous vaccine reactions. These insights are valuable for healthcare providers in discussing potential AEs with patients, thereby improving vaccine compliance and public trust, and for policymakers in planning future booster vaccination strategies.
Bibliographic Study of Biofilm Reactor: An In-Depth Analysis and Future Prospects
Authors: Ding Yuanzhao
Published: January 2024

Biofilm serves as the residence for bacteria, wherein bacteria attach to surfaces and produce extracellular polymeric substances, including proteins, polysaccharides, and extracellular DNA. In recent years, biofilm reactors have gained increasing significance, playing a crucial role, for instance, in immobilizing heavy metals from waterways. This paper employs a bibliographic study to analyze the most important keywords and organizations in the field of biofilm reactors, identifying recent significant papers. Additionally, the paper discusses the opportunities for the future development of biofilm reactors. Through this study, a better understanding of key factors in biofilm reactor research is achieved, providing valuable guidance for future studies and applications in this field.
Skeleton-based Privacy-Preserving Smart Activity Sensor for Senior Care and Patient Monitoring
Authors: Liang Jie , Au Andrew , Chen Minghua , Chan Cyrus , Zheng Jiannan , DeVries Zachary , Xiao Ying , Dhesi Paeton
Published: January 2024

This paper introduces the AltumView Sentinare smart activity sensor for senior care and patient monitoring. The sensor uses an AI chip and deep learning algorithms to monitor the activity of people, collect activity statistics, and notify caregivers when emergencies such as falls are detected. To protect privacy, only skeleton (stick figure) animations are transmitted instead of videos. The sensor is highly affordable, accessible, and versatile. It was a CES 2021 Innovation Award Honoree, and has been selected by Amazon as one of only three fall detection devices integrated into its Alexa Together urgent response service, and has received very positive reviews from Amazon customers. It has also been used in different senior care settings in about ten different countries. The paper presents the main features of the system, the evidences and lessons learned from its practical applications, and future directions.
Advanced Platelet Lysate Aerogels: Biomaterials for Regenerative Applications
Authors: Tibourtine Fahd , Canceill Thibault , Marfoglia Andrea , Lavalle Philippe , Gibot Laure , Pilloux Ludovic , Medemblik Claire , Goudouneche Dominique , Dupret-Bories Agnès , Cazalbou Sophie
Published: January 2024

Human Platelet lysate, a hemoderivative product rich in growth factors, holds significant promise in tissue engineering and regenerative medicine. However, its practical utility in liquid or gel form is hampered by challenges such as limited stability and handling difficulties. This study aimed to engineer dry and porous aerogels from platelet lysate hydrogel using an environmen-tally friendly supercritical CO2-based shaping process customized for tissue engineering appli-cations. The resulting aerogels demonstrated remarkable mechanical robustness and improved manageability. Notably, they exhibited a high-water absorption capacity. Moreover, these aer-ogels exhibited a sustained and favourable biological response in-vitro. They demonstrated the ability to release functional growth factors, sustaining cellular metabolic activity similar to that of conventional culture conditions, even after prolonged storage. Furthermore, they supported the adhesion and proliferation of murine fibroblasts (BALB-3T3) and the migration of Human Um-bilical Vein Endothelial Cells (HUVEC). In addition to serving as excellent matrices for cell culture, these proposed aerogels also function as efficient growth factor delivery systems. This multi-functional capability positions them as promising candidates for various tissue regeneration strategies. Importantly, the elaborated aerogels can be conveniently stored and considered as ready-to-use products, enhancing their practicality and applicability in regenerative medicine
Effect of Land Use Change on Soil Loss by Water Erosion in the Niyang River Basin of Tibet from 1990 to 2020
Authors: Guo Jianbin , Zhang Zhiwei , Yin Huiyan , Hou Lei , Zhang Ying , Xue Qiang
Published: January 2024

The Southwest Alpine Canyon Area of China was one of the regions in the world that suffered from severe soil erosion. The focus of this research was to understand the response of land use change on soil loss by water erosion in alpine canyon on Southeast Tibet, we analyzed the characteristics of temporal and spatial dynamics of land use in the Niyang River Basin from 1990 to 2020 using GIS and statistical methods, assessed the spatial and temporal change characteristics of soil erosion in the Niyang River Basin using RUSLE model. For this purpose, the meteorological, soil, topographic, remote sensing data were collected. The results showed the area of cropland and construction land in the Niyang River Basin increased to 2.4 and 6.1 times the original from 1990 to 2020, respectively, the area of forest and water continued to decrease. Grassland, unused land and forest have always been the dominant land types in the Niyang River Basin. Tolerable soil erosion was distributed in the flat areas of the valley terraces in the main stream and its tributaries, slight soil erosion was mainly distributed in the flat areas at high altitudes, and moderate, severe, very severe and destructive soil erosion was sporadically distributed in the Niyang River Basin. The areas of tolerable and slight soil erosion exceeded 82% of the total area, The area of severe, very severe and destructive soil erosion was less than 6%, but the total soil loss amount of severe, very severe and destructive erosion was more than 27%. From 1990 to 2020, the soil erosion area decreased from 9219.34 km2 to 8,090.84 km2 in Niyang River Basin, more than 85% of the soil erosion class has not changed, and the change of total soil loss amount also shows a significant reduction trend as a whole. 99% of the total soil loss amount in the Niyang River basin is generated by grassland, forest and unused land. The conversion of various land use types to cropland will cause the enhancement in soil erosion grade. We recommend that the focus of soil erosion control in the Niyang River Basin is to protect grassland, forest and carry out scientific farming.
Fundamental Nature and Evolution of Dynamic Dark Energy
Authors: Neukart Florian
Published: January 2024

This paper addresses the Hubble tension in cosmology by exploring dynamic dark energy models, specifically focusing on quintessence scalar fields. We develop a comprehensive theoretical framework for these models, examining various potential forms and their implications for the universe's evolution. We elaborate on the effects of dynamic dark energy on cosmological perturbations, analyzing its influence on the Cosmic Microwave Background (CMB) anisotropies and the formation of large-scale structures. By integrating the theoretical models with observational data, including Type Ia supernovae, CMB observations, and large-scale structure surveys, we investigate the potential of dynamic dark energy to resolve the discrepancies in measurements of the Hubble constant. Our findings suggest that dynamic dark energy models resolve the Hubble tension and have broader implications for our understanding of cosmic evolution and the universe's fate. This study aims to contribute to the ongoing discourse in cosmology, providing a new perspective on dark energy and its role in the expanding cosmos.