bluuebunny/crossref_metadata_2025 huggingface dataset:
An Empirical Study of the Quality Governance Level of China’s Civil Aircraft Industry
Authors: Luo Tingyu , Liu Hongde , Shi Xiang , Meng Peng , Wang Jun , Fang Weiguo
Published: July 2024

The quality governance level of an industry is a multi-index evaluation problem that must consider multiple dimensions and factors. This study is the first to construct a comprehensive quality governance evaluation model for the civil aircraft industry of China (CAIC). The index system for the quality governance evaluation of CAIC was established using a literature review, enterprise investigation, expert interviews, and questionnaire surveys. An Analytic Hierarchy Process (AHP) was employed to determine index weights. Based on the evaluation model, data from 53 aviation manufacturing enterprises were collected, and the quality governance level of the CAIC was empirically evaluated; thus, quantitative and qualitative evaluation results were obtained. This empirical study shows that the quality governance of the CAIC is currently at a “medium to low” level. Furthermore, critical factors and bottleneck indices restricting the quality governance level of the CAIC were identified.
An Integrated CREAM for Human Reliability Analysis Based on Consensus Reaching Process under Probabilistic Linguistic Environment
Authors: Xu Xue-Guo , Zhang Ling , Wang Si-Xuan , Gong Hua-Ping , Liu Hu-Chen
Published: July 2024

Human reliability analysis (HRA) is widely used to evaluate the impact of human errors on various complex human–machine systems for enhancing their safety and reliability. Nevertheless, it is hard to estimate the human error probability (HEP) in reality due to the uncertainty of state assessment information and the complex relations among common performance conditions (CPCs). In this paper, we aim to present a new integrated cognitive reliability and error analysis method (CREAM) to solve the HRA problems under probabilistic linguistic environment. First, the probabilistic linguistic term sets (PLTSs) are utilized to handle the uncertain task state assessments provided by experts. Second, the minimum conflict consensus model (MCCM) is employed to deal with conflict task state assessment information to assist experts reach consensus. Third, the entropy weighting method is used to determine the relative objective weights of CPCs. Additionally, the CPC effect indexes are introduced to assess the overall effect of CPCs on performance reliability and obtain the HEP estimation. Finally, the reliability of the proposed CREAM is demonstrated via a healthcare practical case. The result shows that the new integrated CREAM can not only effectively represent experts’ uncertain task state assessments but also determine more reliable HEP estimation in HRA.
Secure-by-Design Real-Time Internet of Medical Things Architecture: e-Health Population Monitoring (RTPM)
Authors: Marchang Jims , McDonald Jade , Keishing Solan , Zoughalian Kavyan , Mawanda Raymond , Delhon-Bugard Corentin , Bouillet Nicolas , Sanders Ben
Published: July 2024

The healthcare sector has undergone a profound transformation, owing to the influential role played by Internet of Medical Things (IoMT) technology. However, there are substantial concerns over these devices’ security and privacy-preserving mechanisms. The current literature on IoMT tends to focus on specific security features, rather than wholistic security concerning Confidentiality, Integrity, and Availability (CIA Triad), and the solutions are generally simulated and not tested in a real-world network. The proposed innovative solution is known as Secure-by-Design Real-Time IoMT Architecture for e-Health Population Monitoring (RTPM) and it can manage keys at both ends (IoMT device and IoMT server) to maintain high privacy standards and trust during the monitoring process and enable the IoMT devices to run safely and independently even if the server is compromised. However, the session keys are controlled by the trusted IoMT server to lighten the IoMT devices’ overheads, and the session keys are securely exchanged between the client system and the monitoring server. The proposed RTPM focuses on addressing the major security requirements for an IoMT system, i.e., the CIA Triad, and conducts device authentication, protects from Denial of Service (DoS) and Distributed Denial of Service (DDoS) attacks, and prevents non-repudiation attacks in real time. A self-healing solution during the network failure of live e-health monitoring is also incorporated in RTPM. The robustness and stress of the system are tested with different data types and by capturing live network traffic. The system’s performance is analysed using different security algorithms with different key sizes of RSA (1024 to 8192 bits), AES (128 to 256 bits), and SHA (256 bits) to support a resource-constraint-powered system when integrating with resource-demanding secure parameters and features. In the future, other security features like intrusion detection and prevention and the user’s experience and trust level of such a system will be tested.
Testosterone Mediates Reproductive Toxicity in Caenorhabditis elegans by Affecting Sex Determination in Germ Cells through nhr-69/mpk-1/fog-1/3
Authors: Meng Ke , Shi Ying-Chi , Li Wei-Xi , Wang Jia , Cheng Bei-Jing , Li Tian-Lin , Li Hui , Jiang Nan , Liu Ran
Published: July 2024

Testosterone (T), an environmental androgen, significantly disrupts endocrine systems in wildlife and ecosystems. Despite growing concern over its high levels in aquatic environments, the reproductive toxicity of testosterone and its mechanisms are not well understood. In this study, we investigated the reproductive toxicity and mechanisms of testosterone using Caenorhabditis elegans (C. elegans) and assessed its ecological toxicity through the benchmark dose (BMD) method. Our results indicate that T concentrations exceeding 0.01 μg/L significantly reduce the brood size, decrease germ cell counts, and prolong the generation time in C. elegans as T concentrations increase. Furthermore, to elucidate the specific mechanisms, we analyzed the expression of nhr-69, mpk-1, and other genes involved in sex determination. These findings suggest that the nhr-69-mediated reproductive toxicity of T primarily affects sperm formation and the offspring number by influencing its downstream targets, mpk-1 and fog-1/3, which are critical in the germ cell sex-determining pathway. Additionally, this study determined that the 10% lower boundary of the baseline dose (BMDL10) is 1.160 ng/L, offering a more protective reference dose for the ecological risk assessment of T. The present study suggests that nhr-69 mediates the reproductive toxicity of T by influencing mpk-1 and fog-1/3, critical genes at the end of the germ cell sex-determining pathway, thereby providing a basis for establishing reproductive toxicity thresholds for T.
Investigating the Determinants of Mortality before CD4 Count Recovery in a Cohort of Patients Initiated on Antiretroviral Therapy in South Africa Using a Fine and Gray Competing Risks Model
Authors: Mashiri Chiedza Elvina , Batidzirai Jesca Mercy , Chifurira Retius , Chinhamu Knowledge
Published: July 2024

CD4 count recovery is the main goal for an HIV patient who initiated ART. Early ART initiation in HIV patients can help restore immune function more effectively, even when they have reached an advanced stage. Some patients may respond positively to ART and attain CD4 count recovery. Meanwhile, other patients failing to recover their CD4 count due to non-adherence, treatment resistance and virological failure might lead to HIV-related complications and death. The purpose of this study was to find the determinants of death in patients who failed to recover their CD4 count after initiating antiretroviral therapy. The data used in this study was obtained from KwaZulu-Natal, South Africa, where 2528 HIV-infected patients with a baseline CD4 count of <200 cells/mm3 were initiated on ART. We used a Fine–Gray sub-distribution hazard and cumulative incidence function to estimate potential confounding factors of death, where CD4 count recovery was a competing event for failure due to death. Patients who had no tuberculosis were 1.33 times at risk of dying before attaining CD4 count recovery [aSHR 1.33; 95% CI (0.96–1.85)] compared to those who had tuberculosis. Rural patients had a higher risk of not recovering and leading to death [aSHR 1.97; 95% CI (1.57–2.47)] than those from urban areas. The patient’s tuberculosis status, viral load, regimen, baseline CD4 count, and location were significant contributors to death before CD4 count recovery. Intervention programs targeting HIV testing in rural areas for early ART initiation and promoting treatment adherence are recommended.
Immunodeficiency-Related Vaccine-Derived Poliovirus (iVDPV) Excretion in an Infant with Severe Combined Immune Deficiency with Spillover to a Parent
Authors: Mohanty Madhu Chhanda , Govindaraj Geeta , Ahmad Mohammad , Varose Swapnil Y. , Tatkare Manogat , Shete Anita , Yadav Savita , Joshi Yash , Yadav Pragya , Sharma Deepa , Kumar Arun , Verma Harish , Patil Ankita P. , Edavazhipurath Athulya , Dhanasooraj Dhananjayan , Othayoth Kandy Sheena , Puthenpurayil Jayakrishnan Machinary , Chakyar Krishnan , Melarcode Ramanan Kesavan , Madkaikar Manisha
Published: July 2024

In order to maintain the polio eradication status, it has become evident that the surveillance of cases with acute flaccid paralysis and of environmental samples must be urgently supplemented with the surveillance of poliovirus excretions among individuals with inborn errors of immunity (IEI). All children with IEI were screened for the excretion of poliovirus during a collaborative study conducted by the ICMR-National Institute of Virology, Mumbai Unit, ICMR-National Institute of Immunohaematology, and World Health Organization, India. A seven-month -old male baby who presented with persistent pneumonia and lymphopenia was found to have severe combined immune deficiency (SCID) due to a missense variant in the RAG1 gene. He had received OPV at birth and at 20 weeks. Four stool samples collected at 4 weekly intervals yielded iVDPV type 1. The child’s father, an asymptomatic 32-year-old male, was also found to be excreting iVDPV. A haploidentical hematopoietic stem cell transplant was performed, but the child succumbed due to severe myocarditis and pneumonia three weeks later. We report a rare case of transmission of iVDPV from an individual with IEI to a healthy household contact, demonstrating the threat of the spread of iVDPV from persons with IEI and the necessity to develop effective antivirals.
Comparison of Nanoparticles and Single-Layer Centrifugation for Separation of Dead from Live Stallion Spermatozoa
Authors: Bisiau Christian , Moffett Paula , Graham James , McCue Patrick
Published: July 2024

The goal of this study was to compare the efficacy of coated iron-core nanoparticles and single-layer centrifugation for separation of dead from live stallion spermatozoa. Our hypothesis was that nanoparticles would bind to dead sperm and allow for separation from live sperm using a magnet, resulting in a population of spermatozoa with a high percentage of total and progressive motility. Treatment Group 1 was an untreated control. Treatment Group 2 (nanoparticles, NP) utilized sperm incubated with nanoparticles followed by application of a magnet to remove dead sperm adhered to the coated nanoparticles. Treatment Group 3 (single-layer centrifugation, SLC) layered sperm above EquiPure™ followed by centrifugation. Semen samples were subsequently evaluated for sperm motility parameters, plasma membrane integrity, acrosome status, and morphology. The SLC technique yielded higher (p < 0.05) progressive motility (76 ± 9.2%) than the NP separation technique (59 ± 12.2%) or the untreated control (47.3 ± 5.1%). However, the total number of sperm recovered was higher (p < 0.05) in the NP technique (526.2 ± 96.6 × 106) than the SLC procedure (211.7 ± 70 × 106), yielding a higher total number of progressively motile sperm (317.6 ± 109 × 106) recovered using the NP technique than the SLC technique (157.8 ± 43.6 × 106). The percentage of live, acrosome intact sperm recovered was higher for SLC than NP. In summary, the SLC technique yielded a higher percentage of sperm motility, intact plasma membranes, and acrosome integrity, but yielded lower total sperm than with the nanoparticle separation technique.
Challenges and Opportunities of Using Metaverse Tools for Participatory Architectural Design Processes
Authors: Ng Provides , Eloy Sara , Raposo Micaela , González Alberto Fernández , da Silva Nuno Pereira , Figueiredo Marcos , Zuberi Hira
Published: July 2024

Participatory design emerges as a proactive approach involving different stakeholders in design and decision-making processes, addressing diverse values and ensuring outcomes align with users’ needs. However, the inadequacy of engaging stakeholders with a spatial experience can result in uninformed and, consequently, unsuccessful design solutions in a built environment. This paper explores how metaverse tools can help enhance participatory design by providing new collaborative opportunities via networked 3D environments. A hybrid format (online and in situ) co-creation process was documented and analysed, targeting public space design in London, Hong Kong, and Lisbon. The participants collaborated to address a set of design requirements via a tailored metaverse space, following a six-step methodology (Tour, Discuss, Rate, Define, Action, and Show and Tell). The preliminary results indicated that non-immersive metaverse tools help strengthen spatial collaboration through user perspective simulations, introducing novel interaction possibilities within design processes. The technology’s still-existing technical limitations may be tackled with careful engagement design, iterative reviews, and participants’ feedback. The experience documented prompts a reflection on the role of architects in process design and mediating multi-stakeholder collaboration, contributing to more inclusive, intuitive, and informed co-creation.
Computational Simulation of Monopile Scour under Tidal Flow Considering Suspended Energy Dissipation
Authors: Liu Jiawei , Lu Junliang , Liang Zejun
Published: July 2024

Local scour around bridge foundations significantly impacts the stability and safety of marine structures. The development of scour holes adjacent to the pile foundations of sea-crossing bridges, influenced by tidal currents, involves multidimensional physical fields, multiscale coupling, and complex variations in marine loads. However, experimental models alone are inadequate for investigating the underlying mechanisms. Numerical simulation, a critical tool for studying local scour processes, faces the challenge of accurately modeling sediment transport, particularly under tidal flow conditions near pile foundations. To solve this challenge, this research considers the effect of reciprocating flow on sediment shear as well as its characteristic dissipation based on the immersed boundary method, introduces a reciprocating flow dissipation mechanism, and adds a momentum exchange term between the fluid and the sediment to derive a new controlling equation; a new tidal flow localized scour solver is ultimately constructed, termed TidalflowFOAM. The solver effectively simulates complex flow conditions under tidal currents, extending the modeling capabilities to more realistic three-dimensional bridge scour scenarios under combined wave and current conditions. Validation through cases reported in the literature and a series of controlled experiments, encompassing varying depths, flow velocities, and pile diameters, demonstrates the solver’s proficiency in capturing post-vortex data and accurately reflecting the influence of key factors on scour depth. However, the fidelity of the simulated scour hole morphology under tidal flow conditions behind the piles requires enhancement. The proposed numerical model for tidal flow conditions has high solution accuracy and can guide practical engineering applications.
Modeling of Future Streamflow Hazards in Interior Alaska River Systems and Implications for Applied Planning
Authors: Bennett Alec P. , Alexeev Vladimir A. , Bieniek Peter A.
Published: July 2024

There is a growing need for proactive planning for natural hazards in a changing climate. Computational modeling of climate hazards provides an opportunity to inform planning, particularly in areas approaching ecosystem state changes, such as Interior Alaska, where future hazards are expected to differ significantly from historical events in frequency and severity. This paper considers improved modeling approaches from a physical process perspective and contextualizes the results within the complexities and limitations of hazard planning efforts and management concerns. Therefore, the aim is not only to improve the understanding of potential climate impacts on streamflow within this region but also to further explore the steps needed to evaluate local-scale hazards from global drivers and the potential challenges that may be present. This study used dynamically downscaled climate forcing data from ERA-Interim reanalysis datasets and projected climate scenarios from two General Circulation Models under a single Representative Concentration Pathway (RCP 8.5) to simulate an observational gage-calibrated WRF-Hydro model to assess shifts in streamflow and flooding potential in three Interior Alaska rivers over a historical period (2008–2017) and two future periods (2038–2047 and 2068–2077). Outputs were assessed for seasonality, streamflow, extreme events, and the comparison between existing flood control infrastructure in the region. The results indicate that streamflow in this region is likely to experience increases in seasonal length and baseflow, while the potential for extreme events and variable short-term streamflow behavior is likely to see greater uncertainty, based on the divergence between the models.
Dynamics of Saltwater Intrusion in a Heterogeneous Coastal Environment: Experimental, DC Resistivity, and Numerical Modeling Approaches
Authors: Tiwari Prarabdh , Rupesh R , Sharma Shashi Prakash , Ciazela Jakub
Published: July 2024

Saltwater intrusion (SWI) is a critical concern affecting coastal groundwater sources due to natural and anthropogenic activities. The health of coastal aquifers is deteriorated by excessive SWI, mainly caused by the disturbance of the freshwater–saltwater equilibrium due to the escalating population, climate change, and the rising demand for freshwater resources for human activities. Therefore, gaining insight into the dynamics of SWI is crucial, particularly concerning the various factors that influence the intrusion mechanism. The present study focuses on the experimental simulation of saltwater in freshwater aquifers, considering boundary conditions and density-dependent effects. Two geological scenarios within coastal environments were investigated: First, a uniform, homogeneous case consisting of only sand, and second, a heterogeneous case in which layers of sand, clay, and sand mixed with pebbles are used. During the experiment, DC resistivity sounding data, as part of a widely recognized geophysical method, were collected and subsequently inverted to determine the depth of the freshwater–saltwater interface (FSWI). A finite element analysis was employed to generate numerical models based on experimental feedback. Further, for validation purposes, electrical resistivity tomography (ERT) data were collected from two distinct locations: near the seacoast and an aquaculture area. The ERT results show the presence of salinity intrusion in the study area, attributed mainly to groundwater overpumping and fish farming practices. The experimental findings indicate that the advancement of saltwater is affected by the geological properties of the media they traverse. The porosity (ϕ) and permeability (k) of the geological layer play a crucial role during the passage of saltwater flux into freshwater aquifers. The FSWI deviated along the clay boundary and hindered the easy passage of saltwater into surrounding layers. The alignment of experimental, numerical, and geophysical data suggests that this integrated approach could be valuable for studying SWI and can be applied in different geological settings, including tidal flats and alluvial plains.
Application of Dynamic Programming Models for Improvement of Technological Approaches to Combat Negative Water Leakage in the Underground Space
Authors: Lousada Sérgio , Delehan Svitlana , Khorolskyi Andrii
Published: July 2024

The article solves an urgent problem, which is to develop a new approach to finding solutions to improve technological methods to combat negative water leakage in underround spaces. We propose the use of dynamic programming methods to select the optimal technology to secure such spaces. In accordance with the algorithm proposed in this paper, the problem was broken into a number of stages. At each stage, an optimal solution was sought (organisation of transport, delivery of materials to the destination, selection of materials, etc.). Thus, we applied a decomposition approach that allowed us to take into account the variety of parameters that affect the efficiency of the process. All these stages and their corresponding technological solutions were formalised by building network models. In these network models, vertices corresponded to solutions, and the distances between vertices (edges) corresponded to the value of the optimisation parameter. Thus, the shortest route from the initial to the final vertex corresponded to the optimal technological solution to combat negative water leakage in underground spaces. Based on the systematisation of data on technologies to combat water inflow into underground spaces, basic and refined models were developed. These models allowed us to take into account the risks associated with water breakthroughs into underground spaces. To minimise the risks, additional measures to combat water inflows are envisaged. In the practical part of this study, the results of the selection of a method with which to control water inflows are presented. This method involves the use of anchoring to reduce water filtration. According to the results of field observations, no water breakthroughs into the underground space were recorded.
Optimization of Liquid-State Anaerobic Digestion by Defining the Optimal Composition of a Complex Mixture of Substrates Using a Simplex Centroid Design
Authors: Naji Amar , Dujany Arnaud , Guerin Rechdaoui Sabrina , Rocher Vincent , Pauss André , Ribeiro Thierry
Published: July 2024

This study aimed to define the optimal composition of three heterogeneous substrates of the anaerobic digestion process to maximize methane production. The investigated substrates were sewage sludge (SS), the organic fraction of municipal solid waste (OFMSW), and horse waste (HW). The optimal composition of these substrates was defined using the mixture design and, more specifically, the simplex–centroid mixture design. Customized methods and materials were employed to study the complex mixture design of these substrates. The findings revealed that the optimal mixture involved all three substrates with the composition 0.17 HW, 0.66 SS, and 0.17 OFMSW, which demonstrated the highest methane yield at 269 NmL·gVS−1. In addition, a mathematical model was developed to predict methane production based on a specific composition of co-substrates. The results were validated at the small pilot scale.
Efecto de la inteligencia emocional en la salud mental de los trabajadores del Poder Judicial en Iberoamérica
Authors: Nakazaki Simbron Lucía Herminia , Aguilar Espinoza Maira Catherine , Noblecilla Saavedra Judith Nataly
Published: July 2024

El trabajador en las diferentes áreas del poder judicial contribuye a agilizar dicho servicio, mejorando la atención al público, agilizando procesos que redundan en beneficio de los justiciables y a la sociedad en general, en la realización de este trabajo están sometidos a condiciones de estrés, su salud metal depende en gran medida de su inteligencia emocional y de la forma que sea capaz de manejarla. Esta investigación, de enfoque cualitativo, tuvo como objetivo reflexionar sobre la información científica orientada a brindar una visión general de Inteligencia emocional a nivel de Iberoamérica y sus efectos en la salud mental. Para ello, se realizó una búsqueda sistemática en español e inglés con las palabras clave inteligencia emocional, poder judicial, salud metal; arrojando un total de 64900 artículos. Seguidamente, se realizó la depuración a través de la revisión de títulos y resúmenes, quedando 21 artículos. Finalmente, se llevó a cabo el examen del total de los documentos siendo 16 investigaciones las que contaban con todos los criterios de inclusión y calidad, pasando a formar parte del estudio. Las bases de datos empleadas para esta revisión fueron: Scopus, Science Direct, EBSCO, Proquest, Scielo y Redalyc. Los resultados de esta investigación determinaron que, con el beneficio de esta práctica, hubo de reducción de los niveles de agresión de tipo verbal, en comparación, a los efectos alcanzados en agresión física, hostilidad e ira, hacia los usuarios que cuando no maneja la inteligencia emocional
FİZİKSEL AKTİVİTE DANIŞMANLIĞINDA YENİ BİR BAKIŞ AÇISI: “SNACKTIVITY”
Authors: Çelik Zeliha , A. Güzel Nevin
Published: July 2024

Fiziksel aktivite danışmanlığında bireylerin hedeflenen fiziksel aktivite seviyelerine ulaşabilmeleri için kalıcı davranış değişikliğine ihtiyaçları vardır. Bireylerde davranış değişikliği oluşturmak için gerçekçi, uygulanabilir hedefler belirlemek önemlidir. Aktivite atıştırmalığı olarak da bilinen “Snacktivity” yaklaşımı fiziksel aktivite davranışında küçük farklılıklar sağlayarak kalıcı değişiklikleri hedefler. Ayrıca bu yaklaşım günlük hayata uyarlanabilen basit, kısa süreli aktivitelerle sedanter davranışın ve aktivite bariyerlerinin engellenmesine yardımcı olur. Uygun yer, zaman ve ekipman olmadığı için egzersiz yapamadığını ifade eden sedanter bireylerde hiç fiziksel aktivite yapamamaktansa küçük aktivite sürelerinin birleştirilmesi yoluyla hedeflenen fiziksel aktivite seviyesine ulaşılması sağlanır. Toplumda fiziksel aktivite düzeyinin arttırılmasının önemli bir halk sağlığı politikası olduğu düşünüldüğünde “Snacktivity” yaklaşımı kayda değer bir konudur. Bu derleme “Snacktivity” yaklaşımının fiziksel aktivite danışmanlığındaki rolüne odaklanarak farkındalık oluşturmayı hedeflemektedir.
KANSER TEDAVİSİ GÖREN ÇOCUKLARIN ORAL MUKOZİT YÖNETİMİNDE HEMŞİRELİK BAKIM UYGULAMALARI: SİSTEMATİK BİR DERLEME
Authors: Tiryaki Elif , Akay Gamze , Kadiroğlu Türkan , Güdücü Tüfekci Fatma
Published: July 2024

Oral mukozit, çocuklarda sitotoksik kemoterapinin önemli bir komplikasyonudur.Oral mukozitin pediatrik hastalarda önemli morbidite ile ilişkili ve tipik olarak çok ağrılı ve rahatsız edici olduğu bilinmektedir. Mukozit, geleneksel kemoterapi alan hastaların pek çoğunda görülmektedir. Oral mukozitin hastaneye yatışı gerektirecek kadar şiddetli, besin alımının, ağız bakımının ve yaşam kalitesinin azalmasına yol açacak kadar da etkili olduğu bilinmektedir. Günümüzde oral mukozitin tedavi ve bakımında pek çok yöntem kullanılmaktadır. Yapılan bu sistematik incelemenin amacı, 0-18 yaş aralığında kanser tedavisi gören çocuklarda gelişen oral mukozit yönetiminde kullanılan hemşirelik bakım uygulamalarının son 3 yıldaki literatüre katkısını incelemektir. PubMed, Scopus, Google Scholar, Science Direct, Ovid Medline, EBSCO veri tabanları kullanılarak, 2019-2022yıllarıarasında oral mukozit yönetiminde kullanılan hemşirelik bakım uygulamalarını inceleyen Meta-analiz ve randomize kontrollü çalışmalar geriye doğru incelenmiştir. Kullanılan yöntemlerde hemşirelere çok önemli görev ve sorumlulukların düştüğü görülmüştür. Hemşirelerin randomize kontrollü çalışmalar yaparak daha fazla kanıtlar sağlaması çocuklar için çok önemli bir sorun olan oral mukozitin yönetiminde alternatif yollar üreteceğini göstermektedir.
AMELIORATIVE EFFECTS OF BAICALIN AGAINST EXPOSURE TO FLUMETHRIN IN MALE RATS
Authors: Üvenç Esra Nur , Koç Feride
Published: July 2024

Flumethrin is a pyrethroid insecticide, while baicalin is a flavonoid with antioxidant, anti-inflammatory, and anticarcinogenic properties. The aim of this study was to investigate the effects of baicalin on biochemical parameters and lipid peroxidation flumethrin-induced in rats. In the study, 42 rats were divided into six groups with each group comprising seven rats. Flumethrin was administrated 15 mg/kg b.w. to second group, flumethrin+baicalin 50 mg/kg b.w. was administrated to third group, flumethrin+baicalin 100 mg/kg b.w. was administrated to fourth group, baicalin 50 mg/kg b.w. was administrated to fifth group, and baicalin 100 mg/kg b.w. was administrated to sixth group. After, blood and tissue samples were collected for biochemical and histopathological evaluations. According to obtained results, when flumethrin-induced group was compared to control, alkaline phosphatase, cholesterol, blood urea nitrogen, uric acid and total protein levels significantly decreased. Also, kidney catalase and plasma glutatione peroxidase, liver catalase and superoxide dismutase activities decreased, but both kidney and liver nitric oxide and melondialdehyde levels increased in flumethrin-induced group. Flumethrin caused to histopathological alterations in tissues. On the other hand, statistically, kidney catalase and plasma glutatione peroxidase, liver catalase and superoxide dismutase activities increased, but nitric oxide and melondialdehyde levels decreased in all groups given baicalin. In additionally, baicalin affected to some biochemical parameters (p<0.05) and regressed to tissue damage. The obtained biochemical results were consistent with histopathological results. In conclusion, this study suggests that baicalin can ameliorate oxidative stress and tissue damage in flumethrin-induced subacute toxication in rats.
GIDA KATKI MADDELERİ HAKKINDA BİR BİLGİLENDİRME KAYNAĞI OLARAK YOUTUBE VİDEOLARININ DEĞERLENDİRİLMESİ
Authors: Aytekin Şahin Gizem , Kendirli Gamze , Küçüksüllü Elmas Kübra
Published: July 2024

Nüfusun artması ve yemek kültürünün değişmesi ile gıda katkı maddelerinin sayısı ve çeşidi önemli ölçüde artmıştır. Gıda katkı maddelerinin kontrolsüz ve amaçları dışında kullanımını önlemek için çeşitli yasal düzenlemeler olsa da tüketiciler arasında gıda katkı maddelerinin zararlı olduğuna yanlış bir inanç vardır. Ayrıca son yıllarda insanlar sağlık bilgilerine erişmek için interneti daha fazla kullanmaya başlamıştır. YouTube™, beslenme ve sağlık bilgilerine erişmek için sıklıkla kullanılan platformlardan biridir. Ancak paylaşılan bilgiler için ne yazık ki bir denetim mekanizması bulunmamaktadır. Ayrıca gıda katkı maddeleri gibi tartışmalı konularda ortaya çıkan bilgi kirliliği, bu denetimin önemini daha da artırmaktadır. Bu nedenle, bu çalışmanın amacı, gıda katkı maddeleri hakkında bir bilgilendirme kaynağı olarak YouTube videolarını değerlendirmektir. Çalışmaya 96 video dahil edilmiştir. Videonun ismi, linki, yüklenme tarihi, süresi, görüntülenme sayısı, yorum sayısı, beğenme ve beğenmeme sayısı ve yükleme kaynağı bilgileri (Kişisel bloglar, sağlık profesyonelleri ve gıda profesyonelleri) kaydedilmiştir. Daha sonra izlenme oranı, beğenme oranı ve video güç indeksi (Video Power Index-VPI) değerleri hesaplanmıştır. Video kalitesini değerlendirmek için araştırmacılar tarafından oluşturulan İçerik Değerlendirme Skoru, Modifiye DISCERN Ölçeği ve Global Kalite Skoru (Global QualityScore-GQS) kullanılmıştır. Videolar, gıda katkı maddeleri konusunda bilgi sahibi iki araştırmacı tarafından izlenerek değerlendirilmiştir. Çalışmanın temel bulguları, gıda profesyonelleri tarafından paylaşılan videoların GQSve İçerik Değerlendirme Skorunda sağlık profesyonelleri ve kişisel bloglardan daha yüksek puan aldığını ortaya koymuştur (p<0.001). Her üç ölçekte en düşük puan alan videolar kişisel bloglar tarafından paylaşılanlar olmuştur (p<0.001). Ayrıca İçerik Değerlendirme Skoru ile VPI (r=0.308, p=0.002) ve izlenme oranları (r=0.308, p=0.002) arasında pozitif korelasyon olduğu belirlenmiştir. Ancak video kalitesi puanları ile beğenme oranlarının negatif ilişkili olduğu saptanmıştır (p<0.05). Sonuçlar, gıda katkı maddeleri konusunda uzmanlar tarafından yapılan bilgilendirmenin önemini göstermiş olup, YouTube™ platformunda beslenme ve sağlık alanında yayımlanan videoların denetlenmesinin önemini vurgulamıştır.
Alman Medeni Kanunu’nun 126b Paragrafı Çerçevesinde Metin Şekli
Authors: Yağcıoğlu Burcu
Published: July 2024

Değişen ve gelişen teknoloji sebebiyle, hukuki işlemlerin gerek kurulmasında gerek hüküm ve sonuçlarını doğurmasında, alışılmışın dışında bir şekil türünün kullanılmasının yaygınlaştığı gözlemlenmiştir. Hukukumuzda, Tüketicinin Korunması Hakkında Kanun ve bazı yönetmeliklerde, sadece “kalıcı veri saklayıcısı” kavramı ile hukuki bir zemine oturtulan bu şekil türünün hem doktrin hem de kanuni düzenleme boyutu eksiktir. Bu eksikliği gidermek amacıyla çalışmada, Alman ve İsviçre Hukuku kapsamında bir inceleme yapılmıştır. Bu incelemede, bir hukuki ilişkide tarafların beyanlarını kalıcı bir veri saklayıcısı aracılığıyla iletmelerini düzenlemiş olan Alman Medeni Kanunu § 126b ve İsviçre 2020 Borçlar Kanunu Tasarısı m.25 üzerinde durmaya değer hükümlerdir. Metin şekline ilişkin BGB § 126b hükmü, genel ve yürürlükteki bir hüküm olması sebebiyle çalışmamızın esasını teşkil edecektir. İsviçre Hukuku’ndaki düzenleme her ne kadar tasarı niteliğinde kalsa da doktrinin metin şekli kavramını benimsemesi, bazı düzenlemelerde bu şekil türüne yer verilmesi sebepleriyle İsviçre Hukuku da dikkate alınacaktır. Bu çalışma, hukukumuzda eksik olan “metin şekli” kavramını doktrine kazandırmak ve olası bir kanun çalışmasına ışık tutmak amacıyla hazırlanmıştır. Bu kapsamda, özellikle Alman Hukuku bakımından bir şekil türü olarak kabul edilen metin şeklinin geçerlilik koşullarının belirlenmesi ve böylelikle diğer şekil türlerinden farklılıklarının ortaya konulmasıyla gerek tarafların menfaatine gerek hukuki ilişkilerde bundan kaynaklanan uyuşmazlıkların çözümüne de katkı sağlanmış olacaktır.
Enhancing Educational Courses through A Collaborative Learning Management System: A Study on Effectiveness
Authors: Tukiyo Tukiyo
Published: July 2024

This study evaluates the effectiveness of a collaborative learning model integrated with a learning management system in diverse educational contexts. The issue of suboptimal student learning outcomes is often attributed to deficiencies in the development of instructional models and media. The critical role of instructional media in achieving successful learning outcomes necessitates research to bridge the gaps between actual knowledge, theoretical expectations, and practical applications. This study aims to enhance educational models and materials by employing the ADDIE (Analysis, Design, Development, Implementation, and Evaluation) framework for Research and Development. It involved 35 education students and adopted methods such as expert validation, lecturer feedback, and pre-and post-test evaluations for data collection. The analysis covered design, development, testing, and evaluation stages, confirming the developed model's efficacy and functionality. Evaluations by experts in technology and learning models, alongside peer assessments, supported the model's high effectiveness. Preliminary experiments achieved an average score of 88.
Development of Visionary Leadership Training Module for State Senior High School Principles
Authors: Siregar Sakinah Ubudiyah , Akmaluddin Akmaluddin , Hanim Siti Aisyah , Nasution Siti Lam'ah , Syara Lili
Published: July 2024

This study aimed to develop and evaluate a visionary leadership training module for principals at a public senior high school in Labuhan Batu. Specific objectives included creating the module, designing its content, assessing its feasibility, and gauging the principals' responses. The research employed a developmental approach, focusing on enhancing the principals' skills in vision articulation, decision-making, creativity, communication, motivation, empowerment, emotional intelligence, change management, role modeling, and understanding the organizational climate. With a confidence level of 95% and a significance level of 0.05, the study surveyed a total population of 84 individuals. The findings indicated the training module effectively fostered the desired leadership qualities. The module's development and its reception among the principals were both rated as very good, affirming its potential to foster visionary leadership in high school settings.
Refining Indonesian Language Sound Pronunciation Skills Using InPhA (Indonesian Phonetic Alphabet)
Authors: Jayanti Cicik Tri
Published: July 2024

Interference from regional language pronunciation results in imperfections in pronouncing Indonesian language (IL) sounds. This phenomenon is experienced by students taking the Indonesian Language Phonology course (ILPC), where using IL pronunciation media is needed to enhance personal correction skills. The average scores for consonant, vowel, and diphthong pronunciation phonemes are low. Hence, this research aims to achieve three main objectives: (1) Enhancing students' vowel sound pronunciation skills using InPhA in the ILPC; (2) Enhancing students' consonant sound pronunciation skills using InPhA in the ILPC; and (3) Enhancing students' diphthong sound pronunciation skills using InPhA in the ILPC. This research employs a qualitative research design by implementing Classroom Action Research procedures. The data sources include 67 students from the Indonesian Literature Department, A Public University in Malang, Batch of 2022. The data includes scores for the Assessment of Indonesian Vowel, Consonant, and Diphthong Pronunciation in the pre-cycle, cycle one, and cycle two phases. The research findings indicate that the Average Improvement of Indonesian vowel allophone sound pronunciation consisting of [i], [I], [u], [U], [e], [ɛ], [Ә], [o], [ɔ], and [a] is 35.54%; the Average Improvement of Indonesian consonant sound pronunciation involving 23 consonants namely /p/, /b/, /m/, /f/, /w/, /t/, /n/, /l/, /r/, /ḍ/, /∫/, /s/, /z/, /c/, /j/, /n̴/, /y/, /k/, /g/, /ŋ/, /x/, /h/, and /ʔ/ is 11.5%; and the Average Improvement of Indonesian diphthong sound pronunciation comprising four allophones namely [aI], [ai], [aU], and [oi] is 11.5%. All three aspects demonstrate that using InPhA media can enhance Indonesian vowel, consonant, and diphthong sound pronunciation skills in the ILPC.
Collaborative Learning Integrated Pancasila Profile Based on Cultural Diversity to Improve Critical Thinking Ability
Authors: Yani Risky Putri , Tirtoni Feri
Published: July 2024

Critical thinking is the ability to analyze, interpret and evaluate information objectively and rationally needed in the 21st century to face future challenges through innovative approaches in order to take advantage of opportunities in the digital and global era. Critical thinking skills at the elementary school level are still low and need to be improved through collaborative learning according to the implementation of the independent curriculum. The profile of Pancasila students is the skills that Indonesian students must have based on the noble values of Pancasila. This study aims to test the application of collaborative learning integrated with the Pancasila student profile based on cultural diversity with the Project Based Learning learning method to improve critical thinking skills. This study uses quantitative research pre-experiment method of one group pretest-posttest design. The subjects of this study involved 18 grade 4 students who were divided into small groups and calculated using the N-Gain test. The N-Gain test is a measuring technique to determine the effectiveness of a treatment before and after learning. The results of this study found the overall average N-Gain results showed moderate criteria between 0.3≤g≤0.7 and quite effective at a percentage between 56-75. Another result of this study, by doing collaborative learning students can become peer tutors and innovate to complete projects given by teachers from the development of an independent curriculum integrated with the Pancasila learner profile. Therefore, collaborative learning integrated with the Pancasila learner profile is concluded to improve critical thinking skills.
Integrating Human Resources Management and Digital Competencies: A Strategic Approach in Higher Education
Authors: Rohayati Teti
Published: July 2024

This paper explores the integration of Human Resources Management (HRM) and digital competencies as a strategic approach in higher education institutions. In this context, "digital competencies" refer to the ability of individuals to use digital technologies effectively and efficiently, encompassing a broad range of skills from basic digital literacy to advanced technical proficiencies. "Digital skills," on the other hand, are specific abilities required to operate digital tools and platforms, including data analysis, software usage, and online communication. Given the rapid advancement of digital technologies, higher education is at a pivotal juncture to embrace these changes to enhance administrative efficiency and academic excellence. The study utilizes a systematic literature review encompassing academic journals, industry reports, and policy documents to examine current practices and theoretical frameworks that align HRM with digital competencies within the sector. Key findings suggest that a strategic integration of digital skills in HRM not only optimizes operational processes but also fosters an environment conducive to digital learning and innovation. The research highlights several critical strategies, including the development of digital training programs for staff, the inclusion of digital competency frameworks in HR policies, and the strategic recruitment of tech-savvy personnel. Engagement with various stakeholders, such as faculty, administrative staff, and students, is crucial for the successful implementation of these strategies, ensuring that the institution's digital transformation aligns with the needs and expectations of its community. The paper concludes with recommendations for higher education leaders to cultivate a digitally competent workforce that can navigate and thrive in a technologically driven educational landscape. This approach is imperative for institutions aiming to maintain competitiveness and relevance in the digital age.
Efektivitas Algoritma Kruskal dalam Mengoptimalkan Jalur Terpendek pada Jaringan Intranet
Authors: Ar Ruhimat Qurrota A'yuni , Slamin Slamin , Malinda Alvira
Published: July 2024

This research takes a case study at the Communication and Information Service, Bondowoso Regency, which is one of the media for conveying information and connecting interactive communication between the government and the community. In the process of conveying information to the public, they utilize information technology, the Intranet Network. The problem found was that there were obstacles in ineffective cable installation. This relates to non-optimality in determining the shortest path between two points in an intranet network, and how to determine the correct wiring position, so that the amount used is minimal but can still function optimally and be connected to all computers. To overcome the problems above, in this research the Kruskal Algorithm will be applied which is one of the network optimization methods in Graph Theory. Graph Theory is one of fields in Mathematics that studies the relationships between objects and how these objects interact with each other. Meanwhile, the Kruskal algorithm is an algorithm used to find the shortest path between two points in a graph. It is hoped that this research can optimize the amount of cabling used in designing intranet network topologies so that we can design optimal intranet routes with minimal costs.
Sensitivity enhancement of hydrogen-gas sensor by sub nm Au on Pd surface of a wireless quartz resonator
Authors: Nagakubo Akira , Matsukura Tokiya , Ogi Hirotsugu
Published: July 2024

Hydrogen (H2) is an important source of next-generation energy production. The various H2 sensors developed to date cannot easily detect very low concentrations of H2 (<10 ppm) at room temperature within 100 s. In this study, we develop H2 sensors by depositing a 200 nm thick palladium (Pd) film on AT-cut quartz resonators and adding a sub nm gold (Au) layer on the Pd surface. Moderate Au deposition on the Pd surface improves the sensitivity of the sensor by decreasing the activation energy of atomic-hydrogen migration from the surface to the subsurface. The optimal Au thickness that minimizes the activation energy is 0.5 nm. Finally, we show that the approximate detection limit at room temperature is 5 ppm.
About social contradictions
Authors: Chernavskiy M. Yu.
Published: July 2024

The article analyzes the nature of social contradictions from the positions of Marxism methodology and structuralist psychoanalysis. Dialectical analysis of Marxist interpreted contradictions allows the author to reveal the essence of industrial capitalism. Structuralist psychoanalysis in understanding the nature of social contradictions makes it possible to investigate the question of Russia’s retrograde return to capitalism and is able to explain the functioning of the modern capitalist system of global exploitation through the use of mechanisms of ideological phantasm. The procedure of neutralization of contradictions in modern Russian society is carried out by converting economic contradictions into political ones and through the implementation of the idea of “export of chaos”.
Challenges of team building in the context of digitalization at production facilities
Authors: Khomiakov D. V. , Pecheritsa E. V.
Published: July 2024

The article deals with the fact that the progress of scientific research and the evolution of the global economic environment in the XXI century has caused significant transformations in the paradigms of the functioning of organizations, generating new strategies for doing business. Particular attention is paid to the study of the dynamics of the formation of command structures in the conditions of digital transformation, which necessitates a comprehensive scientific analysis, especially in the perspective of remote work organization. In this context, the digital space becomes a predominant arena of interaction, which affects the structuring and development of social interrelationships within organizations. The article investigates the process of team building and interaction in the organization in the conditions of digitalization, as well as the active introduction of the remote format of work in its activities. The study includes the stages of team formation, the impact of offline and online interaction, employee satisfaction, problems and decisions made by managers to compensate for the shortcomings of digitalization. The results indicate the need for further research in the areas of virtual collaboration skills, organizational culture management, and leadership adaptation to remote work environments to optimize virtual team processes.
Problems of legal regulation of the norm on occupation of the highest position in the criminal hierarchy
Authors: Kosyanenko E. V. , Trukhin M. A.
Published: July 2024

The publication is devoted to the critical analysis of the structure of the corpus delicti stipulated by Article 210.1 of the Criminal Code of the Russian Federation (CC RF). Based on the results of the review of the norm the authors conclude that there is no act in it, which violates the basic provisions of criminal legislation. In the current construction of the corpus delicti the moment of its termination in practice is shifted to the beginning of the norm. The correlation of the act provided for by part 4 of article 210, article 210.1 of the Criminal Code of the Russian Federation is argued. The boundaries of these crimes are indicated. It is argued that gradual adaptation leads to smoothing of legal defects of the composition, but this process is not able to solve all problematic aspects of Art. 210.1 of the Criminal Code of the RF.