New-onset atrial fibrillation and chronic coronary syndrome in the CLARIFY registry
Authors: Gautier Alexandre , Picard Fabien , Ducrocq Gregory , Elbez Yedid , Fox Kim M , Ferrari Roberto , Ford Ian , Tardif Jean-Claude , Tendera Michal , Steg Philippe Gabriel ,   CLARIFY investigators, Guerrero A Ahuad , Basara M , Belcastro F , Bertarini J A , Cazenave C , Dreycopp H , Egido J , Estrella J , Garofalo D , Giordano J , Lagioia H , Lago N , Greca R La , Lema L , Cabanillas N Lopez , Luquez H , Miller C , Prada E , Rodenas P , Schena R G , Suarez G , Tomatti A , Colquhoun D M , Conradie A , Cox S , Cross D , Fathi R , Fitzgerald B , Hamilton-Craig I , Holt G , Jayasinghe S R , Mai N , Moolman J , Motyer R A , Phillips K , Rafter A , Rahman A , Rainbird A , Scalia G , Taylor A , West P , Alford K , Amor R , Astridge P , Bastian B , Bates F , Doohan M M , Du Plooy J , Ford J C , Kanagaratnam L , Khoury V , Parkin R , Rogers J , Sceats G , Waldman A , Wang D , Wright S , Ardill J , Aylward P , Beltrame J F , Bradley J , Heddle W , Joseph M , Rajendran S , Varughese S , Brice E , Hockings B , Janssen J , Kozlowski A , O'Shea J , Tan J , Playford D A , Woollard K , Ajani A , Barron G , Better N , Carruthers T , Chan B , Chan R , Cotroneo J , Counsell J T , Eccleston D S , Forge B H R , Hamer A , Horrigan M , Jelinek V M J , Lew R , O'Donnell D , Panetta F , Sebastian M , Shetty P , Soward A , Srivastava P , Strathmore N F , Sylivris S , Szto G , Veth V , Yip T , Badr-Eslam R , Kleemann L , Steurer G , Mörz-Proszowski B , Auhser F , Teleky U , Sepp G , Beinhauer A , Kerö D , Lavicka C , Perger T , Hadjiivanov V , Feldner-Busztin M , Mika R , Filip W , Mahr A , Toplak J , Millauer M G , Haralambus P , Walcher K , Karner K H , Ziak E , Painsipp P , Frank U , Suntinger A , Gritsch W , Bode G , Herrmann R , Raffelsberger R , Topf H , Moser E , Föchterle J , Honsig T , Mayr K , Mayr H , Kaserbacher R , Dzien A , Galehr E , Felbermayer M , Schwarz R , Amini R , Appeltants H , Ballet A , De Niel C , Berkenboom G , Bernard X , Bouvy T , Claeys M , Dascotte Y , Davin L , De Backer T , De Meester A , De Ridder S , Dendale P , Denef K , Emonts M , Geraedts J T M , Goethals M , Grégoire J-M , Herbots T , Hoffer E , Hutse W H J , Lafontaine P , Lefebvre P , Lesseliers H , Odent G , Pasquet A , Peperstraete B , Purnode P , Rogowsky A , Rosseel M , Salembier J-P , Surmont P , Vandeplas A M F , Van De Walle S , Van den Branden F , Vandergoten P , Vanhauwaert B G , Vanneste L , Vercammen J , Verleyen D , Vermander D , Weytjens C , De Lorenzo A Rocha , Issa A Felice Castro , Mioto B Mahler , Vianna C de Brito , Okawabata C , Rossi E Giusti , Fernandes F , Pitella F , Cesena F Henpin Yue , Ferreira J F Monteiro , Junior J F , Tonet L , Cesar L Machado , Gowdak L H , Matos M A , Moretti M , Amato R Vicente , Munhoz R Tadeu , Coimbra S R , De Lorenzo A Rocha , Issa A Felice Castro , Mioto B Mahler , Vianna C de Brito , Okawabata C , Rossi E Giusti , Fernandes F , Pitella F , Cesena F Henpin Yue , Ferreira J F Monteiro , Junior J F , Tonet L , Cesar L Machado , Gowdak L H , Matos M A , Moretti M , Amato R Vicente , Munhoz R Tadeu , Coimbra S R , Luqman H N , Yakovova S , Mantcheva M , Mincheva V , Baurenski L , Karastanev K , Yordanova V , Peneva Y , Wong P , Fagan M , Sabe-Affaki G , Villasenor F M , Son W K , Manyari D E , Giacomantonio N , Lubelsky B J , Ezekiel D , Leong J C S , Grover A , Vavougios J , Pesant Y , Kushner A M , Yeung M M W , Vertes G E , Nasser-Sharif F J , Spensieri D , Roy A , Nguyen T T , Leclair M , Morra P , Biglow C Everton , Baril J F , Lai K , Wong D S , Martinho V , Antoniadis G A , Searles G R , Rouse D , Brisson G , Wong S King , Collette R S , Ho M S C , Constance C , Gendreau R , Kellam G W , Lara T A Cieza , Boyrazian H A , Shamsuzzaman M , Spink D R , T Wong A P , Janes J , Czarnecka M , Saulnier D , Levesque G , Clavette P F , Kokis A , Orenstein-Lyall T L , Pandey A Shekhar , Robb J , Verret G , Czarnecki W , Perreault F , Chouinard G , Lafrance G , Fullerton G M , LeBouthillier P , Tran Q H , Marrero I Rodriguez , Ramadan F B , Talbot P , Fazil M A , Cha J Yi-Ming , Garg S , Chehayeb R , Roy B , Chan Y K , Harlos H E , Matheson H B , Patel R , Vaz G F , Bhatt J S , Liu E , Ashton T H , Sullivan H , Quinn L P , Yared K , Gupta A K , Sullivan B , Campbell J , Pallie S , Kim H H , Savard D , Cherry J M , Gold J , Brouillette G , Belanger A , Berlingieri J , Nisker W , Boutros G , Bakbak A I , Lasalle L , Chen L L , Chen M H , Chen M Y , Chen X P , Chen Y D , Cong H L , Ding S F , Dong J T , Dong S H , Du Z M , Feng L L , Gao W , Ge H , Ge S J , Guo T , Guo Y , Huang Z , Huo Y , Jin H G , Ke Y N , Li H W , Li H M , Li Z C , Li Y J , Liu J L , Liu Q L , Liu S W , Lv S Z , Miao W , Pan G Z , Pu X D , Qian Z M , Su X , Tao J H , Wang H P , Wang J A , Wang N F , Wang T , Wang W , Wang Y , Wei M , Wu S Y , Wu Y J , Xiong L G , Xu D , Yan J , Yang K , Yang M , Yang T L , Yang X L , Yu J M , Zeng H S , Zhang H , Zhang H Q , Zhang L , Zhou S X , Zhou Y L , Bozkova J , Carda J , Dedkova S , Dufka A , Fridrich J , Hodac T , Jirmar R , Kadleckova A , Karlicek M , Krupicka J , Kuchar J , Lavicka V , Leso J , Lorenc Z , Micko M , Navratil P , Petrova I , Povolna P , Raisova L , Raska P , Ravlyk V , Schlesingerova S , Smrckova E , Sternthal P , Stursova H , Vymetal P , Wiggers P , Markenvard J , Andersen L K , Frost L , Refsgaard J , Strange S , Egstrup K , Sykulski R , Hildebrant P , Haghfelt T , Ege M , Saaby L , Cattan S , Adam-Blanpain M , Adda M , Aimouch N , Ardouin L , Assouline S , Aumjaud A , Barjhoux C , Baroudi R , Beaurain C , Bennouna M A , Bernard A , Bernardeau C , Blanc E , Blum-Decary I , Bodur G , Boesch C , Bonal J , Bonhomme R , Bonnet J L , Bories J , Bourachot M L , Brumelot F , Petaut M Brunehaut , Brunschwig C , Buffet P , Calmettes P , Centa I , Chartier B , Chemin P , Chometon F , Cohen J , Colin R , Cottin Y , Crespo F , Dabboura A , David F , Dehayes P , Dematteo P , Dibon O , Dodemant P , Dormagen V , Dreyfus X , Dubois J M , Duclos F , Ducoudre M , Duprez O , Durand P , Durand E , Egloff P , Escande M , Berdou M C Escourrou , Ashari G Esna , Feldmann I , Ferrieres J , Foltzer E , Fontanet B , Garandeau M , Garban T , Geffroy S , Gillet T , Godart S , Gosse P , Gratia P , Greiner O , Gueusquin A , Guiu E , Guy J M , Haddad S , Hennebelle V , Honorat S , Hourany A , Hua G , Jacquier P , Jean S , Jeremiasz R , Kohler P , Lacroix A , Leandri M , Lemiere Y , Liautard M , Loheac P , Louchart J C , Magnus P , Maheu B , Malaterre H R , Manchet G , Mantoux J , Manzi D , Marachli M , Maroun M , Meneveau N , Messas E , Mougeolle J L , Mouhat T , Muller J , Naisseh M , Nocon P , Onger D , Ouguoujil A , Ovize M , Page E , Pareathumby K , Pleskof A , Poinson P , Pons G , Pouderou P , Poujois J N , Probst V , Prunier F , Prunier L , Puel V , Rechtman D , Rennert R , Rijavec B , Riou Y , Robert J , Roche C , Roul G , Salaun B , Saleh B , Sandalian A , Sander M , Schenowitz A , Silvestre A , Soleille H , Tabet S , Tardy M , Thomas-Richard F , Truong B , Varaldi J , Vial H , Walch J M , Wazana M , Zeitouni R , Audibert H , Alizon F , Amlaiky A , Asplanato M , Baranes C , Bariaud M , Bernasconi F , Bousquet P , Ceraulo C , De Geeter G , Donetti J , Doucet B , Doucet J , Dutoya T , Ennouchi D , Fallacher M H , Fouquet G , Fourchard V , Gdalia J , Grollier G , Guerard S , Jeannerat P A , Jobic Y , Joulie V , Jourdain P , Jouve V , Ketelers R , Khaznadar G , Kohan P , Koujan B , Lammens B , Landragin I , Moal E Le , M'Bey D , Maes F , Morlet S Maheas , Massabie R , Meddah D , Meriaux F X , Mestre-Fernandes C , Meyssonnier P , Migliore M , Milewski J , Millet J F , Mingam S , Nazeyrollas P , Paganelli F , Pellerin F , Petitjean F , Pinzani A , Pladys A , Primot P , Pucheu A , Rahali A , Ravoala P , Rousson D , Samama P , Sardon M , Silvestri R , Soskin P , Tabone X , Tricot C , Vaquette B , Vogel M , Weingrod M , Aboyans V , Amoretti R , Aubry J , Berthezene P , Binet D , Bonnaud X , Bonnet P , Bonny A , Bouchaya T , Boureux C , Bourgeois J M , Brottier L , Cavert B , Cleron S , Dechoux E , Delhomme C , Detienne J P , Dubs J P , Faudon B , Fellous F , Fressonnet R , Garaud Y , Garcia D , Geneves M , Gleizes J L , Guyetand C , Hermellin B , Iovescu D , Kanner J P , Khanoyan P , Leherissier A , Maximovitch A , Merian B , Messali P , Moreau Y , Moyal J , Payot L , Peuch L Petoin , Prevot J L , Raymond P , Relange D , Reymond S , Robert J F , Rosenstein H , Schneider J , Schultz R , Tanielian P , Thoin F , Thomas L , Touzet P , Steg G , Sauvinet G Amiel Oster , Domengetroy F Baylac , Chamou K , Etcheverry B , Farges J L , Fraboulet J Y , Goralski M , Janody D , Mamez B , Manlay W , Paillard F , Pelier F , Petit A , Skonieczny M , Augarde R , Fournier J B , Liandrat S , Lim P , Noury A I , Paris D , Saade M , Stordeur J M , Danchin N , Pornin M , Fauchier L , Galinier M , Balice-Pasquinelli M A , Sosner P , Yvorra S , Delcoulx E , Mouquet F , Poulard J E , Sudre A , Heno P , Biausque F , Guenoun M , Attia G , Pouwels S , Carpentier L , Verbrugge E , Ziccarelli C , Elkohen M , Tricoire J , Lang P , Huttin O , Altevogt B-M , Altmann U , Baar M , Berrisch-Rahmel S , Birkenhagen A , Bläse I , Blindt R , Bosch R , Brattström A , Breuer H-H , Castrucci M , Cicek-Hartvig S , Cierpka R , Claus M , Deissner M , Drexler M , Eggeling T , Eisele G , Enayat D , Frickel S , Gessner S , Giokoglu K , Gmehling J , Goss F , Grooterhorst P , Gysan D B , Haberl R , Haerer W , jun N Hassler , Heinemann-Meerz S , Henschel F , Hinrichsen M , Hofer W , Hofmeister A , Hoh G , Horstkotte E , Jäger F , Jeserich M , Keil U , Killat H , Kimmel S , Kindel M , Kindler P , Kleta S , Könemann J , König K , Krause-Allmendinger H , Kronberg K , Kruck I , Männl V , Meinel A , Mentz G , Meyer-Michael E , Mibach F , Möller S , Muth S , Nelböck-Huber E , Ohlmeyer D , Özkan-Rashed Z , Paulus C- P , Perings S , Placke J , Raters C , Reifart N , Rink A , Rybak K , Salecker I , Schermaul K-H , Schlesinger-Irsch U , Schmidt E , Schmitz K-H , Schön N , Schröder T , Sievers B , Simon M , Spengler U , Speth-Nitschke M , Stumpp A , Szabo S , Taggeselle J , Tamm A , Thelemann A , Thelemann C , Thümmel H , Unger G , Utech A , Volmar J , Wauer B , Wehr G , Weinrich L , Weinrich R , Windstetter U , Wirtz J H , Wittlich N , Ziehn P , Zündorf P , Wahshi Y Al , Singh P P , Narayan A , Tamimi F Al , Yazeedi J Al , Ayche M , Lawati A Al , Dhanki M Al , Salustri A , Salah T , Tamimi M Y , Agrawal A , Wassef A , Baslaib F , Radaideh G Al , Yusufali A , Bazargani N , Akbar M , Wahab H Abdel , Malak S Abdel , Ghaly I , Hafez H , Kandari F Al , Haiba M , Alanbaei M , Gomaa M M , Khalifa A , Avgerinos C , Gouli O , Stergiou D , Alexopoulos I , Pappas C , Petropoulos I , Chatzioakim G , Pontikakis N , Priftis C , Mpompoth P , Bourazanis I , Papathanasioy A , Avlonitis S , Zakopoulos C , Koutsimpanis G , Tsamopoulos I , Christoforidis C , Zachos V , Kalaras P , Karachaliou M , Liatas C , Pournaras G , Theodorakis G , Orestis I , Panisois K , Chalkiadakis E , Arfaras V , Kolios G , Boutsikos P , Kotsalos A , Mitropoulos D , Samothrakitis A , Svolis K , Anastasiou E , Gkinis T , Dalampyras P , Kalampalikis A , Leontaridis I , Gabriilidis S , Konstantinidis I , Plastiras V , Tarenidis P , Marozsán I , Édes I , Czuriga I , Cziráki A , Tóth K , Dongó Á , Túri P , Forster T , Borbola J , Bachmann B , Masszi G , Orbán M , Gerges G , Balogh G , Bajcsi É , Takács I , Nagy L , Kisjós B , Jánosi A , Nagy A , Nagy K , Büttl A , Lippai J , Sziegl Zs , Malkócs Zs , Földi A , Fikker K , Szabó E , Forrai R , Sebõk Z , Merkely B , Gupta R , Natarajan S , Dalal J , Saran R K , Mehta A , Samal M P , Khan I A , Ghose T , Sawhney J P S , Roy T , Chandra S , Modi S , Singh M M , Vijayaraghavan G , Murthy L Sreenivasa , Ramesh S S , Dayasagar Rao V , Chenniappan M S , Vadavi A , Kunhali K , Reddy K Srinivasa , Vallal Su Thillai , Khera P , Prasad B , Shukla D , Trivedi A K , Ahuja R , Rawal J , Karnik R , Hiremath M S , Kumbla D K , Shetty S R , Chonkar N S , MJuneja Late , Goyal B K , Sheahan R , Daly C , Vaughan C , Fleming S , Shiels P , Keelan P , Kiernan T , Day B , Kelly K , MacNamara F , Maguire B , Clifford A , O'Gara A , Guardigli G , Pes G , Caridi G , Frattola A , Doronzo B , Riccioni G , Lacchè A , Massari F , Orazi S , Carretta D , Provvidenza M , Pedretti R , Nicolino A , Felis S , Pernice V , Gaglione A , Gori P , Martina P , d’Alessandro V , Giacomazzi F , Terrosu P , Cernetti C , Antonicelli R , Ansalone G , Balbi M , Tamburino C , Moretti L , Tantillo S , Patriarchi F , Proietti F , Sinicropi G , Maragoni G , Mallamaci V , d'Este D , Azzolini P , Brscic E , Bongo S , Gigantino A , Perna G , Mayer M S , Rosa C La , Muscio G , Scollo V , Magliari F , Pio C Petrillo , Castellari M , Pasquale P Di , Scalzo Dr , Saporito F , Capuano N , Alitto F , Marchionni N , Turiel M , Bianco A , Greco C , Marullo L , Testa R , Vicentini A , Novo S , Varra F La , Tavazzi L , Conte M R , Lazerevic Z , Colivicchi F , Macchi C , Mule J Dalle , Sibilio G , Achilli A , Proto C , Kang S M , Koo B K , Hong S K , Kim W , Lee S H , Yoo B S , Seo H S , Gwon H C , Kang D H , Kwon H M , Chae I H , Oh S J , Shin J H , Goh C W , Byun Y S , Zo J H , Hong T J , Kim D S , Cha T J , Ryu J K , Kim Y J , Hwang J Y , Hur S H , Jeong M H , Oh S K , Jin D K , Jung K T , Rhew J Y , Lee S , Jeon D W , Yoon S J , Kim S H , Mintale I , Latkovskis G , Hansone S , Rozkova N , Baika A , Jasinkevica I , Abele S , Laizane I , Pontaga N , Ecina V , Mihailova I , Kondratovica A , Laucevičius A , Jurgaitienė R , Šlapikas R , Barauskienė G , Jankauskienė E , Revienė S , Zaronskienė D , Šlapikienė O B , Kupstytė N , Rinkūnienė E , Steponėnienė R , Kojelienė J , Badarienė J , Dženkevičiūtė V , Sadauskienė E , Butkuvienė I , Stankevičius R , Paliulionienė R , Snikytė R , Mažutavičius R , Jamaluddin A N , Rahim A A Abdul , Yusof A K Mohamed , Chee K H , Sadiq M A , Ramanaidu S , Sim K H , Ong T K , Fong A Y Y , Chang B C , Chua S K , Cham Y L , Amin N H Mohd , Tan S K , Khiew N Z , Said A , Abdullah C K , Cheah Y W , Sinnadurai J , Lau K K H , Choor C K , Sia K K , Ang C C , Singh J S Awtar , Wahab M Z Abdul , Wong C K , Ghapar A K , Muthu A , Mahendran K A , Jaafar A H , Ng K H , Ruhani A I , Tahir H A R , Manap H Abdul , Ch'ng B S K , Ch'ng E T , Abdullah A S , Ismail O , Sahar A S , Kareem B B Abdul , Kader M A Sheikh Abdul , Ma S K , Chan K K , Goh T H , Singh A , Liew H B , Chu C M , Bhaskaran R K M , Shah R P , Joseph K L , Hasni H Noor , Ng W K , Choo G H , Saaidin N , Yeo C K , Lai V M , Lai Y C , Tay M H , Lim B A , Luqman H N , Esperon Guillermo Llamas , Alvarez J de Jeús Zuñiga Sedano y America , Manzur F Azar , Sánchez C Jerjes , Rojas J Cerda , Calvillo J Carrillo , Aranguren F Petersen , Sánchez C Martínez , Sangabriel A Álvarez , Vieyra G , Romero S González , Barragán A Puente , Escalante F Redding , Paez J Chávez , Valadez E Fernandez , Gaxiola E , Manautou L E , Otero O Henne , Bustillos M Barrera , Pons J L Leyva , Álvarez E Gómez , Santana J R Romo , Redding J Martínez , Mendoza A Arias , Briones I Rodríguez , Arellano J de Jesús Rivera , León J L Arenas , Gamba M Alcocer , Alexanderson E , Esparza M E Ruíz , Sifuentes L A Elizondo , Briseño J L , Rodriguez E Sandoval , Delgado M L Fuantos , Navarrete S Sandoval , Juarezy U Casas , Pinales A Loera , Castro A , Carpio R Cue , Rodríguez E , Rojas G , Solache G , Juárez R Díaz , Baleón R , Solorio C Ferreyra , Reyes H A Ramírez , Martínez M López , Maldonado M A Romero , de la Peña J Escobedo , Orozco J Hilario Jiménez , Cisneros F A Reyes , Gil J Álvarez , López G Bautista , Ibarra M Odín de los Ríos , I Tulevski I , Somsen G A , Miedema K , Chlewicka I , Brodzicki P , Stasiuk T , Szałkowski P , Kulig W , Maliszewski M , Królicka K , Zdrojewska J , Nikodemska I , Szpak A , Wrębiak-Trznadel M , Prokop A , Szulc M , Olszewski A , Kępa W , Banach J , Węglarz M , Gałuszka-Bilińska A , Królak A , Cisowska-Drozd E , Orzechowski K , Jeżewska M , Adamaszek K , Glanowska G , Pitsch T , Matuszewska G , Nowowiejska-Wiewióra A , Dereń M , Walawski G , Sołtysiak M , Wysocki R , Jarosiński G , Drzewiecka A , Ługowski T , Jankowska A , Błaszczak P , Drozd J , Łotocka E , Duchowska R , Sobczyk D , Jarmużek P , Sidor M , Adamczyk-Kot D , Sudnik J , Cygler J , Skoczylas I , Poprawa B , Kisiel L , Kossowska U , Sikorska-Buczkowska B , Modzelewska K , Demianiuk B , Streb W , Mularek-Kubzdela T , Bogdański P , Kaźmierczak E , Zimoląg R , Lorenc J , Furtak R , Regulska A , Winter M , Fic M , Turek P , Nowicka E , Bryl W , Lenartowska L , Jerzykowska O , Maćków M , Gadziński W , Kacorzyk R , Zalewska D , Sadłowski R , Słaboszewska J , Gruchała M , Frankiewicz A , Walczewska J , Adamkiewicz-Piejko A , Chyrek R , Jankowska L , Correia A , Girão A , Herdade Á , Sequeira A , Taveira A Tavares E , Gonzaga A , Ribeiro A , Albuquerque A , Fernandes A , Estriga A , De Almeida A Rocha , Lourenço A , Pereira A , Faria A , De Moura B Carvalho , Camossa C , Alves C , Aguiar C , Rodrigues C , Wellenkamp E , De Sousa F Fernandes , Pinto F Moreira , Matias F , Alves G Silva , Bragança G , Proença G , Pêgo G Mariano , Vinhas H , Arroja I , Morais J , Sá J Silva E , Vasconcelos J , Matos J , Freitas J , Ferreira J , Costa J , Alcaravela J , Mimoso J , Antunes J , Dos Santos J Ferreira , Dos santos J Nobre , Fernandes J , De Aguiar J Chambel , Moreira J , Carvalho J , De Carvalho J Forte , Calaça J , Simões L , Antunes L Lopes , Soares L , Semedo L , Macedo L , Sargento L , Basto L , Rebelo L , Oliveira L , Carvalho M Catarino , Costa M Alves , Gamboa M C , Vasconcelos M F Ferrão E , Custódio M H , Mendonça M I , Vaz M J Pinto , De Macedo M Espiga , Lazaro M , Oliveira M Martins , Pelicano N , Lousada N , Rodrigues O , Dias P Matos , Fonseca P F , Ferreira P , Abreu P Farto E , Monteiro P , Gomes R Seabra , Carvalho R , Santos R , Soares R Rosado , Baptista S , Monteiro S Reis , Gil V , Sanfins V , Martins V , Anghel M , Georgescu C Arsenescu , Babes K , Banu M , Beyer R , Bratu I , Bumbu A , Capalneanu R , Chioncel O D , Chiscaneanu T , Christodorescu R , Nica N Cindea , Cinteza M , Coman S , Constantinescu M , Craiu E , Dan G A , Dan D C , Dan A , David C M , Dorobantu M , Farcas D , Firastrau V , Florescu C , Ghicu A , Giuca A , Grigoriu R , Ionescu D D , Iosipescu L C , Ivan M V , Lighezan D , Magheru S , Magherusan M , Marinescu S M , Motoc A C , Musetescu R , Rau M , Rus L Rotaru H , Sirbu O , Sorodoc L , Spinu C M , Stanciulescu G , Statescu C , Toringhibel M , Trambitas R , Trocan N , Tudose A , Vinereanu D , Zagreanu M , Motomancea R , Militaru C , Dymova D , Semenova N , Zherebtsova A , Fedoskin V , Gurianova N , Bolotova N , Knyazeva V , Spitsina T , Sytilina N , Atamanchuk N , Giorgadze M , Zarechnova S , Kutuzova S , Sharapova Y , Stelmakh I , Sinyukova O , Rostik S , Evtukhova L , Sukhanova L , Makhieva T , Tereshko S , Kolesnikov V , Kochurov E , Marchenko B , Nurgalieva S , Galeeva Z , Andreicheva E , Zakirova V , Baleeva L , Minsafina A , Borodina N , Arkhipova Y , Krechunova T , Scherbak M , Merkhi A , Aksyutina N , Ratovskaya O , Suglobova E , Kozhelenko Y , Potapova E , Poluyanova G , Naberezhnova N , Daniels E , Atueva K , Tsaryabina L , Kurekhyan A , Khishova N , Dubinina E , Demina O , Mochkina P , Bukanina E , Tolpygina S , Polyanskaya Y , Malysheva A , Kheliya T , Serazhim A , Voronina V , Lukina Y , Dubinskaya R , Dmitrieva N , Kuzyakina M , Khartova N , Bokuchava N , Smirnova E , Esenokova A , Pavlova Y , Smirnova O , Astrakhantseva P , Bykovskaya S , Charikova O , Berdnik K , Karaseva T , Zhabina L , Oleinikova N , Dzhkha O , Grigoryan S , Yakovenko E , Ivaschenko T , Kiseleva I , Shokina T , Novikova M , Khodanov A , Popova L , Latyntseva L , Kilaberiya O , Makarenkova K , Nosova N , Gerasimova T , Boikova L , Sharapova N , Kulikova Y , Pasechnaya N , Bulakhova E , Kurochkina S , Bratishko I , Likhobabina O , Panova E , Voronina N , Bizyaeva N , Gusev O , Nevolina N , Arsentieva T , Budanova I , Melnikova E London , Khripun A , Polyaeva L , Osadchuk E , Krasnoslobodskaya O , Yakimova N , Lugin A , Sosnova Y , Il'ina E , Kositsina G , Shanina I , Kostomarova S , Malgina M , Omelchenko M , Gorlova I , Eidelman S , Salakhova A , Bondarenko B , Sopia R , Baboshina N , Eliseeva N , Tumarov F , Petrochenko N , Khudina I , Arabadzhi N , Samakhovets V , Tkhorzhevskaya L , Sinotova T , Zherlitsyna E , Minkin S , Petrova N , Tikhonov Y , Shmakova N , Abduvalieva V , Kuzmicheva M , Nikolaeva L , Varezhnikova O , Dmitrieva T , Mikhailova E , Yanina Y , Kapustina L , Vazhdaeva Z , Golovina G , Fedorova N , Nikolaeva I , Fillipova O , Gareeva L , Tuktarova F , Khmelevskikh N , Karnot V , Golub M , Surovtseva I , Kulygina V , Shelomova N , Kruglova I , Pokrovskaya I , Rodina O , Polkina L , Biryukova N , Filippova E , Kotova E , Ignatieva T , Alekseeva T , Gruznykh L , Mozerova E , Moksyuta E , Kosachek E , Srtumilenko N , Baranova O , Voronova T , Bayakhchan L , Grudtsina I , Gorshkova L , Shamsutdinova O , Getman M , Gorodilova I , Karnaukhova N , Rotenberger V , Isaeva L , Lebischak G , Ryzhkova V , Usoltseva E , Mescharekova D , Tavlueva E , Mineeva E , Stikhurova M , Kosareva L , Grechishkina O , Nikishina S , Ilyukhina A , Gureeva O , Soin I , Erofeev S , Lebedev S , Kudryavtsev l , Gamzatov E , Maximchuk N , Grekhova L , Kolevatova L , Kazakovtseva M , Kolesova O , Zharikova L , Kukaleva V , Starostina N , Grushetskaya I , Kazachkova V , Pashentseva I , Shimonenko S , Sirazov I , Chernozemova A , Golubeva O , Mingalaeva S , Zatsarina E , Kozlov D , Davydova N , Larina O , Alhabib K F , Hersi A , Al-Backer H , AlFaleh H , Mobeirek A , Arafah M , Al-Shamiri M , El-Shaer F , Zaibag M Al , Bdeir M , Suliman I , Mukhtar A , Omar H , Jamiel A , Elkrail A , Alanazy M , Habab M , Ashmak K , Nourallah R , Mak K H , Singh B , Chee T S , Koo C C , Low L P , Nair V P , Ng K S , Quek S S S , Tan E H M , Ng A L R , Chuang H H , Kamensky G , Kaliska G , Murin J , Hatalova K , Gaspar L , Simkova I , Dubrava J , Pjontek J , Pella D , Banikova A , Szentivanyi M , Kovar F , Benacka J , Gonos I , Fazekas F , Kycina P , Poles J , Fras Z , Pernat A , Veternik A , Černič-Šuligoj N , Kerbev M , Krajnc I , Zagožen P , Alam A , Brown B , Luke B , Variava E , Nethononda R , Joubert S , Matthews P , Nkombua L , Antia V , Naidoo D P , Bhayat J , George S K , Ranjith N , Vawda G H M , Govender S , Soosiwala I , Shein K , Panajatovic M , Flores J , Khan M S H , Blignaut S , Coetzee K , Burgess L , Freeman V , Theron H D , Vives M A Arnau , Oliva F J Abardía , Carrascosa P Aguar , Martínez V Albero , Colomer J M Alegret , Ezquerra E Alegría , Fernández C A Almeida , Recalde N Alvarenga , Auñon A Alvarez , García P Alvarez , Fernández C Amo , Galito C Amoros , Viguiristi R Ancín , Feal M Aparici , Capell A Ardiaca , Pardo J Arnedillo , García G Arquero , Esteban V Arrarte , Alonso M Baquero , Pérez P Barahona , Mayor J L Bardají , Alvarez V Barriales , Celorio A Batalla , Martín B Berzal , Valero D Bierge , Castiñeiras J Blanco , Ojeda F Bosa , Penas C Botana , Redondo H Brufau , Cortada J Bruguera , Solé R Cabrera , Iglesias F Calvo , Miguel S Cantabrana , Cardoso R Carrillo , Pié M Casanovas , Giménez P Casas , Lueña E Castillo , Moreno J A Castillo , Orive M Castillo , González A Chirivella , Alcubilla J M Chopo , Payá V Climent , Gil M A Cobos , Martín J L Colomer , Clemente A Concepción , Sánchez R Cortés , Luengo D Cremer , Soler S Darnes , Novales J de Andrés , Aritmendiz R De Castro , Baguda J de Juan , López M de los Reyes , Prieto J L Delgado , Díaz J L Díaz , Cervantes C Escobar , Sasieta J Ezcurdia , Rubio L Facila , Salvador C Falces , Zaragoza P Federico , Alvarez R Fernández , de la Cigoña F Fernández , Lázaro L A Fernández , Léoz L C Fernández , Mouzo R Fernández , Gómez M Fernández-Valls , Rodríguez B Ferreiro , Aranda C Franco , Corzo J Freire , Alonso J Fuertes , Beneitez J Fuertes , Basilio E Galve , García C García , Martínez M J García , González M J García , Ortego S García , Pindado C García , Saavedra V García , Marimón J García-Moll , Rubia R Gascueña , Lorente D Gentille , Pavón H Gervas , Gómez R Gilabert , Barrado J J Gómez , Doblas J J Gómez , Martinez M J Gómez , Juanatey C González , Toda V González , Ortega M Gonzalvez , Higuero E Gordillo , Afonso J Hernández , Fernández D Herrera , Espinach E Homs , Gastearena A Idoate , Latasa M Irurita , González R Izquierdo , Herter M Jaquet , Carballo M Lagares , Galán J A Lastra , González B Limeres , Aranda M A López , Barreiro L López , Gómez D López , Granados A López , Mouriño V López , López-Sendón J L , Méndez M Luaces , Latorre L Mainar , Araez E Marín , Ortuño F Marín , Santana A Martín , Florez J Martínez , González J Martínez , Rivero J F Martínez , Martín D Marzal , Mignaqui G F Mazzanti , Pita A Melero , Laborda E Molina , Escrivá G Miñana , Saavedra V Montagud , Gaspar Mª A Montero , Robles J Mora , González J Morales , Arribas J Moreno , Casquete Mª T Moreno , López C Moya , Eizagaechevarría N Murga , García F Narro , Manchón J Navarro , Navas C Navas , García E Novo , Gamero J A Núñez , España A Ordóñez , López J A Ortiz de Murua , Soler E Orts , Chulian E Otero , Torres L Pastor , Sánchez A J Paule , Bermejo M A Paz , del Moral V Pedrosa , Pérez G Peña , Egido J Á Perea , De Isla L Pérez , Ibiricu S Pérez , Martínez Mª A Pérez , Paredes M Pérez , Domingo E Peris , Cubero A M Peset , Sopena J Pinar , Rodríguez C Pindado , Lozano Mª J Pinilla , Ramírez C Piñero , Ramos Y Porras , Moriche E Prieto , Ariznabarreta F Ramos , Gutiérrez M Rayo , Catalán J M Roca , Almodóvar A Rodríguez , Collado J Rodríguez , Fernández A Rodríguez , Fernández J A Rodríguez , Hernández J A Rodríguez , Tejero I Rodríguez , Castillejo I Romeo , Alvira D Romero , Hinojosa J A Romero , Menor C Romero , Sevillano P Rossi , Calle E C Rueda , Soriano J Rueda , Pérez P Ruiz , Gorostiza T Sagastagoitia , Hidalgo I Sainz , Rollán M Sandin , Rodríguez S Santaolalla , Olmeda E Santas , Iglesias J L Santos , Rodríguez M L Sanz , Laborda I Segura , García S Serrano , Toral B Sevilla , Melchor L Silva , Martín-Ambrioso E Simarro , Casado R Sola , Navarro C Soriano , Ruiz Mª I Soto , Calle P Talavera , Fernández E Teijeira , Díaz P L Torres , Gil A Troncoso , Berraquero F Trujillo , Martínez M A Ulecia , Sánchez J Umaran , Herreros C Vaticón , García A Vázquez , Barbado J L Vega , Espejo-Saavedra E Velasco , Vera T Vicente , Gutiérrez M Vida , Mariscal C Villar , Boniato G Vives , Amen L Wu , Bowden G Yanes , Wonenburger J C Yañez , Gómez J L Zamorano , Navarro J Zarauza , Monnier P , Jaussi A , Forclaz A , Grobéty M , Schlueter L , Vuille C , Nacht C A , Evéquoz D , Ciaroni S , Dominé F , Bérubé J , Rickli H , Hellermann J , Koller R , Bourgeois G , Engel R , Niederberger C , Stadler P , Gnädinger M , Schmied C , Wettstein T , Hilti P , Chételat C A , Sepulcri F , Brunner H , Schindler J , Kraus M , Vivekaphirat V , Panpunnung S , Kuanprasert S , Wongcharoen W , Phrommintikul A , Harinasuta J , Si O , Chaithiraphan V , Boonyasirinant T , Boonyapisit W , Kittipovanonth M , Buakhamsri A , Piyayotai D , Hutayanon P , Junejo S , Aiyegbayo O , Ancliff H , Bradshaw C , Cervenak R , Choi H , George E , Gilmour I , Gough D , Idrissi-Sbai A , Ingham J , Al-Khalidi B , Liston A , Mackrell J , Pattison I , Ramachandran R , Ray N , Reddy G , Sen I , Shetty K , Singh L , Stanley M , Wallace A , Weatherhead M , Gilbert T , McCansh G , Higgins S , Killeen C , Cromarty I , Franklin P , Pinch E , Dhesi A , Dernedde C , Lawrence M , Simper H , Noble M , Dalton G , Stevens L , Berry P , Hand C , Oliver R , Jones H , Sampson P , Taylor N , Grogono R , Dalrymple J , Martin A , Thurston S , Elsby K , Vallis M , Morrison G , Lang C , Watson A , Thomson A , Dougall H , Hay B La , Compson L , McCracken A , Calder J , Weber F , Richmond D , Brownlie R , Brown G , MacCowan H , Heap A , Perry M , Holden L A , Scott G , Haldane N , Hood S , Cullen I , Bell J , McNaught P , Sharif M , Dunn J , Hay D , Ross S , Shaw R , Hay L , Langridge S , Burns R , Crawford L , Kennedy A , Logan D , McAlavey P , Brown M , Costello P , McLaren G , Potter A , McPherson J , Drijfhout M , Finlayson J , Troup D , Woodall A , Pearce J , Williams S , Parkar W , Yusuf A , Benett I , Bishop P , Thomas H , Caldwell I , Ormiston P , Kwok S , Wright S , Kanumilli N , Saul P , Milligan H , Wilkinson I , Vance A , Paul N , Paul C , Shaikh I , Ellis R , Vites N , Steeds R , Goodwin D , Aftab A , Banham S , Chauhan N , Grocutt M S , Gupte A , Jordan R , Jheeta B S , Ladha K , Nazir M , Pal R , Patel R P , McManus R , Singal A , Saunders P , Syed A B , Bahal A , Dau H , Walker D M , McNeilly R , Bolidai A , MacCarthy N , Lawton D , Vardhani M , Sengupta G , Kinloch D , Howie F , Serrano-Garcia A , Paget S E , Till R , Seal P , Morrell J , Maxwell T , Singh G , Warden D , Elias R , Dixon C , Pandey R K , Challenor V , Davies S , Gibbs M , Gillet A , Goldie C , Jarvis I , Johnson P , Malden M , Moore J , Morton C , Nehrig K , Sheringham P , Wilson G , Halcox J , O'Connor I , Ling K , Edwards D , Charles H , Weatherup A , Davies E , Watkins N , Morgan D , Davies R , Lindsay A , Beacock D , Balai R , Kirmond P , Brindle P , Bundy C , Cahill T , Dayani A , Eavis P , Mohr S , Hayne S , Krasucki C , Micheals M , Orpen I , Parker I , Sewell R , Sharp D , Smith A , Stevens A , Upton J , Victory J , Wernham C , Davis R , Mays C , Andrews M , Takhar J , Travill C , Choudhury P , Matta W , Ihonor A , O'Dong C , Rahman S , Singer P , Gillam S , Bath P S , Razzaq N , O'Toole O , Rowe P , Williams H , Kalra P , Allcock A , Tucker A , Sprott V , Kyd K , Cunliffe G , Arden C , Bateman A , Kassianos G , Sinclair D , Turner C , Jagathesan R , Sattar F , Ashford A , Chukwu A , Taylor H , Pradhan R , Rundell T , Howlett R , Bietzk R , Patel R , Myint M , Partington M , O'Reilly F , Baverstock M , Dixon S , Tennekoon M , Brand N , Haimes P , Keller P , Whetstone S , Davis R , Mays C , Andrews M , Takhar J , Parker L , Anscombe M , Beale G , Murphy L , Smith A , Brown S , Lindford J , Serrano A , Preston S , Sethi R , Hutchinson S , Kovyrshyna O , Rogozhyna V , Kiver T , Vasylenko V , Kucheryava L , Salimova S , Alekseenko V , Gukov O , Myhailiv I , Kardashevskaya L , Prikolota O , Bashkirtcev O , Andreev E , Tkachenko L , Mospan M , Batushkin V , Reshotko D , Safonova L , Ogorodnichuk A , Pustovit S , Romanov S , Burlakova L , Voloshko Y , Lafarenko V , Vlasuk Z , Leshchuk O , Chushak S , Koval V , Stasuk O , Pogrebna O , Kornienko S , Tikhonova S , Fesenko T , Kuzmina T , Ushakov O , Vechtomova N , Potapska L , Illushechkin I , Kryvenkova E , Lysunets O , Tsygankov O , Bardachenko L , Voloshyna L , Ginzburg V , Franskyavichene L , Korotich T , Vyshnevaya N , Bilous N , Kulinich S , Kulik V , Sadykova I , Zalyzniak O , Berezhna T , Molotyagina S , Nguyen L V , Pham M H , Pham H T , Khong N H , Do K B , LE T B , Do P A , Do T C , Nguyen N Q , Do Q H , Vu K C , Pham N H , Pham T H T , Ta M C , Phan D P , Nguyen T T H , Pham T T N , To T L , Le V T , Dang L , Bui L , Pham T T H , Phan H H , Bui T T H , Tuong T V A , Nguyen T P , Nguyen T H , Nguyen B K , Vu D B , Pham N S , Do T Q , Pham T S , Dang V D , Le D T , Do V C , Nguyen T K L , Luong H D , Luu T Q , Pham N V , Huynh T K , Tu N T H , Ngo K A , Nguyen T T C , ONG T T L , Doan V B , Kim T B , Vo T N , Tran T T T , Nguyen T A , Tran V D , Nguyen A K , Tran A C , Ngo M H , Vu N H , Ly I T , Tran N P H , Tran L U P , Nguyen T N , Tran T H , Truong P H , Mai T L , Hoang V S , Bui C M A , Dang V P , Truong Q B , Vo M P , Nguyen V T , Chau N H , Ta T T H , Dinh H N , Tran H , Nguyen H K N , Chung A , Chung E , Martina-Hooi B , Angela R , Ramoutar P , Fillet R , Tilluckdharry R , Dookie T , Foster E , Hart C , Omardeen F , Ramphall S , Lalla C , Henry R , Cheng J , Elliott V , Falconer H , Hurlock-Clarke L , Ishmael R , Lalljie G , Lee K , Liqui-Lung A , Massay R , Mohammed H , Brown C , Daniel R , Didier M 
Published: August 2023

Background and aims

Data on new-onset atrial fibrillation (NOAF) in patients with chronic coronary syndromes (CCS) are scarce. This study aims to describe the incidence, predictors, and impact on cardiovascular (CV) outcomes of NOAF in CCS patients.

Methods

Data from the international (45 countries) CLARIFY registry (prospeCtive observational LongitudinAl RegIstry oF patients with stable coronary arterY disease) were used. Among 29 001 CCS outpatients without previously reported AF at baseline, patients with at least one episode of AF/flutter diagnosed during 5-year follow-up were compared with patients in sinus rhythm throughout the study.

Results

The incidence rate of NOAF was 1.12 [95% confidence interval (CI) 1.06–1.18] per 100 patient-years (cumulative incidence at 5 years: 5.0%). Independent predictors of NOAF were increasing age, increasing body mass index, low estimated glomerular filtration rate, Caucasian ethnicity, alcohol intake, and low left ventricular ejection fraction, while high triglycerides were associated with lower incidence. New-onset atrial fibrillation was associated with a substantial increase in the risk of adverse outcomes, with adjusted hazard ratios of 2.01 (95% CI 1.61–2.52) for the composite of CV death, non-fatal myocardial infarction, or non-fatal stroke, 2.61 (95% CI 2.04–3.34) for CV death, 1.64 (95% CI 1.07–2.50) for non-fatal myocardial infarction, 2.27 (95% CI 1.85–2.78) for all-cause death, 8.44 (95% CI 7.05–10.10) for hospitalization for heart failure, and 4.46 (95% CI 2.85–6.99) for major bleeding.

Conclusions

Among CCS patients, NOAF is common and is strongly associated with worse outcomes. Whether more intensive preventive measures and more systematic screening for AF would improve prognosis in this population deserves further investigation.