bluuebunny/crossref_metadata_2025 huggingface dataset:
The Renewable of Low Toxicity Gelcasting Porous Ceramic as Fe2O3 Catalyst Support on Phenol Photodegradation
Authors: Putri Suriati Eka , Pratiwi Diana Eka , Tjahjanto Rachmat Triandi , Hasri  , Andi Irhamsyah , Rahman Abd , Ramadani Andi Indra Wulan Sari , Ramadhani Anita Nur , Subaer  , Fudholi Ahmad
Published: September 2022

Low toxicity gelcasting water-based method was conducted using a non-acrylamide system, with cassava starch and natural clay as poregenic agent and raw material, respectively, and the resulting porous ceramic was used as Fe2O3 catalyst support. The concentrations of cassava starch used were 1%, 3%, 5%, 7%, and 9%, the sintering process was performed based on the results of TGA/DTA thermal analysis. In addition, the sol-gel coating method was used to impregnate the Fe2O3 catalyst into the porous ceramic. BET results show that the pores formed in the ceramic body are micro pores with a size range of 21.41-23.27 Å, hence the concentration of cassava starch does not affect the pore characteristics. The morphology of SEM results also indicated the presence of pore formation in the ceramic body. According to the quantitative XRD analysis, the cassava concentration affects the percentage of catalyst impregnated. The highest percentage of Fe2O3 catalyst on 7% cassava starch was 41.15% and the phase of the catalyst successfully impregnated was α-Fe2O3with a rhombohedral structure. In addition, the highest percentage of phenol degradation was 59.15% with good performance after 8 times of recycling. In this study, we provide for the first time, utilization of Fe2O3-porous ceramics with a wonderful performance of recycling ability in the process of phenol photodegradation.
An Ethical Perspective of Animal Rights Protection in Indonesia
Authors: Pinilih Sekar Anggun Gading , Sitepu Hymne Gloria P. , Saraswati Retno , Tyesta ALW Lita
Published: September 2022

An environment is a meeting place for every living creature. They have an important role in respecting each other's rights in the environment. One of the living creatures in the environment is fauna. As part of the environment, fauna also has rights that must be fulfilled in the environment to avoid fauna becoming rare and even extinct. However, nowadays, many types of fauna are becoming rare and even on the verge of extinction. Of course, this is also caused by the pace of human development with all its interests in the environment. Often, human interest underestimates the existence of rare and even endangered fauna. To overcome this, humans must have an awareness of the rights of fauna. One of the steps that can be taken is to incorporate moral awareness into the legal domain. Therefore, to build moral awareness in the conservation of endangered species, it is hoped that there will be regulations that can accommodate all of them. Simply, to build moral awareness of animal rights, a law that specifically guarantees animal rights is needed, if necessary, to guarantee its constitutionality in the state constitution.
Effect of Maitake D-fraction in advanced laryngeal and pharyngeal cancers during concurrent chemoradiotherapy: A randomized clinical trial
Authors: Hu Qinglei , Xie Binli
Published: September 2022

Background: Concurrent chemo-radiotherapy (CCRT) is an ideal treatment for advanced head and neck squamous cell carcinoma (HNSCC). The performance of CCRT induces severe toxicities in HNSCC patients and decreases the quality of life (QOL). Maitake D-Fraction is proteoglycan which has anti-tumor function associated with its immunomodulatory capacity. The polysaccharides of Maitake also have anti-radiation effect in radiation therapy during cancer treatment. This research aimed to illustrate Maitake D-Fraction effects on CCRT-associated adverse events and QOL. Methods: During CCRT, Maitake capsules were taken orally 3 times a day, each time 4 capsules, one hour before meals. QOL were analyzed by EORTC QLQ-C30-Chinese version and EORTC QLQ-H&N-35-Chinese version. 141 patients were recruited and divided into an intervention group and a placebo group. Results: Frequencies of severe CCRT-associated adverse events in intervention group were less than in placebo group. Global QOL score in intervention group was higher than in placebo group 5 weeks post treatment. The proportion of patients returning to baseline global QOL score at 6-month was increased by Maitake D-Fraction administration. Conclusion: In conclusion, this randomized clinical trial demonstrated that in advanced laryngeal and pharyngeal cancer patients, the oral administration of Maitake D-Fraction alleviated CCRT-related adverse events and deterioration in QOL.
Examining the Relationship between Work Stressors and Auditors’ Job Performance
Authors: Ali Norlela Mohd , Ghani Erlane K
Published: September 2022

Workplace stress is a common problem in all types of occupations, and from the highest to the lowest levels of management. Auditors are not an exception to stress, particularly for those working in audit firms. To mitigate the auditors’ stress level, it is crucial for the management to identify work stressors on their job performance. This study aims to examine the relationship between work stressors and auditors’ job performance. Specifically, this study chose five potential work stressors namely, role ambiguity, work overload, time pressure, work/family conflict and salary and compensation. Using a questionnaire-based survey of 102 auditors, this study shows that role ambiguity and salary and compensation have a significant relationship with auditors’ job performance. On the other hand, this study shows that work overload, work/family conflict, and time pressure do not have a significant relationship with auditors’ job performance. The findings in this study provide an understanding for management of the work stressors that could affect the auditors’ job performance. Understanding this would assist the auditors to manage their stress properly, which could positively improve their performance.
Curriculum Development in the United Arab Emirates
Authors: Ridge Natasha , Kippels Susan , Farah Samar
Published: September 2022

With an increasing emphasis on youth development and employability in the Middle East, the United Arab Emirates (UAE) has made a substantial effort to re- imagine and reform its public education sector. Local education authorities have implemented many reforms to try to shift education from rote memorization toward a skills-based system that prepares students to thrive in the 21st century. This policy paper explores the history of curriculum development in the UAE, the role of various agencies, ministries, and current initiatives as well as the challenges and possibilities that lie ahead on the road of reform. It concludes with recommendations for policymakers relating to the implementation of sustainable curriculum reforms.
Compost made with household waste, an alternative for fertility in Urban Organic Garden
Authors: Masabanda J, Chipantiza
Published: September 2022

The objective of the research is to elaborate compost with household waste as an alternative for fertility in urban organic gardens. The study was carried out at the Escuela Superior Politécnica de Chimborazo, Sede Orellana, Ecuador; with the participation of the students of the career of Agronomy, Environmental Engineering and Zootechnics. The materials used were household waste such as eggshells, remains of vegetables and fruits, waste of animal origin, among others. The research was based on a quantitative explanatory approach with an experimental method and design, because some samples were taken and analyzed experimentally in a laboratory. According to the results, the objective of the research was fulfilled; however, it is convenient to improve the humidity composting parameters; this means that you must regulate the humidity, either by supplying water to the material or by adding fresh material with higher water content.
Keywords: Compost, household waste, fertility, organic gardens, eggshells, other vegetables.
Resumen La investigación tiene como objetivo elaborar el compost con residuos del hogar como una alternativa de fertilidad en los huertos orgánicos urbanos, el estudio se realizó en la Escuela Superior Politécnica de Chimborazo, Sede Orellana, Ecuador; con la participación de los estudiantes de la carrera de Agronomía, Ingeniería Ambiental y Zootécnica. Los materiales utilizados fueron residuos del hogar como cáscaras de huevo, restos de verduras y frutas, residuos de origen animal entre otros. La investigación se basó en un enfoque cuantitativo de tipo explicativa con método y diseño experimental, porque se tomaron algunas muestras que fueron analizadas en un laboratorio experimentalmente. De acuerdo a los resultados, se cumplió con el objetivo de la investigación; sin embargo, es conveniente mejorar los parámetros de compostaje de la humedad; esto significa que debe regular la humedad, ya sea proporcionando agua al material o añadiendo material fresco con mayor contenido de agua.
Palabras Clave: Compost, residuos del hogar, fertilidad, huertos orgánicos, cascaras de huevo, resto de verduras.
Higher Education in Times of Pandemic. Experiences at the Orellana de la ESPOCH Headquarters
Authors: Santillán-Lima J. , Caichug-Rivera D. , López Paredes C.
Published: September 2022

Education worldwide has been modified and led to new teaching canons due to the presence of the pandemic caused by COVID 19. Therefore, the objective of this research is to study the impact of COVID 19 on higher education, in this special case in the Higher Polytechnic School of Chimborazo, Sede Orellana. For this, the enrollments were analyzed from 2019 to the present, 30 students and 3 teachers from the different careers were interviewed. The main result is that the campus has been gradually increasing its students, reaching 911 students today, more than double that of 2019. This has increased more strongly in the pandemic. The teachers, in agreement with the students, affirm that careers should be created that allow not only face-to-face education, but also virtual education that allows education to be more widespread. So also that hybrid education be considered that combines virtuality with face-to-face to promote careers that require face-to-face practices, such as zootechnics, tourism, agronomy, among others.
Keywords: Covid 19, education in pandemic, Study in pandemic.
Resumen
La educación a nivel mundial se ha visto modificada y llevada a nuevos cánones de enseñanza debido a la presencia de la pandemia ocasionada por el COVID 19. Por lo cual el objetivo de esta investigación es estudiar el impacto del COVID 19 en la educación superior, en este caso especial en la Escuela Superior Politécnica de Chimborazo, Sede Orellana. Para ello se analizó las matrículas desde el 2019 hasta la actualidad, se entrevistó a 30 estudiantes y 3 docentes de las distintas carreras. El principal resultado es que la sede ha ido incrementando de manera paulatina sus estudiantes, llegando a tener 911 estudiantes en la actualidad, más del doble que en el 2019. Llegando a incrementar con mayor fuerza en la pandemia. Los docentes en coincidencia con los estudiantes afirman que se deben crear carreras que permitan que no solo la educación presencial, sino que se debe optar por una educación virtual que permita que la educación sea más extendida. Así también que se considere la educación hibrida que conjuga la virtualidad con la presencialidad para potenciar las carreras que necesitan de manera obligatoria practicas presenciales, como lo es la zootecnia, el turismo, agronomía entre otras.
Palabras Clave: Covid 19, educación en pandemia, Estuiar en pandemia.
Editorial
Authors: Editorial Board ESPOCH
Published: September 2022

This is an Editorial and does not have an abstract. Please download the article PDF or view it in HTML.
Spatial and temporal variation of bacterial population in ambient air particulate matters (PM2.5, PM10 and TSP) of Isfahan city, Iran
Authors: Soleimani Mohsen , Shirani Farzaneh , Jalali Seyed Amir Hossein
Published: September 2022

Introduction: Airborne particles are considered as an important indicator of outdoor air quality. Many health problems have been linked to high concentrations of Particulate Matters (PMs) and their associated microorganisms. The aim of this study, therefore, was to investigate the population of bacteria in PMs in various times and locations.
Materials and methods: The PM samples including PM2.5, PM10 and Total Suspended Particles (TSP) were taken from 4 different stations of Isfahan city, Iran on February (cold season) and July (warm season), 2019 using an air sampling pump on culture media. The number of bacterial colonies was counted after 48 h growth in the incubator at 37 oC. The PMs concentration and some morphological characteristics of bacteria were also investigated.
Results: The highest number of bacterial colonies was in TSP followed by PM10 and PM2.5. The bacterial populations at two stations in north and east. of the region in the warm season were higher than in the cold season, and the respective situation in the other two stations at south and center of the city was reversed, which seems somehow to have been the result of the PMs concentration of difference of pollution sources in various locations and seasons.
Conclusion: This study highlights the importance of PMs pollution especially PM2.5 (i.e. the main factor affecting the air quality of the study area) as the carrier of microbial pollution in the air which could adversely affect human health.
​Performance of Pigeon Pea [Cajanus cajan (L.) Millsp] Genotypes under Cold Stress
Authors: Tiwari T.N. , Dutta D. , Tewari Kalpana
Published: September 2022

Background: In north India, pigeon pea experiences low temperature stress during winter months (December-January). Information’s regarding cold stress and its impact on morphological characters, physio-biochemical processes and yield attributes in pigeon pea crop is very limited. Keeping the above facts in to consideration, the experiment was formulated to screen suitable genotypes of pigeon pea tolerant to cold stress based on morpho-physiological traits and ability to set flower and pods and yield performance. Methods: Field experiments with 98 genotypes of pigeon pea were conducted in augmented design including checks with all recommended cultural practices in 2018-19 and 2019-20 at New Research Farm, ICAR-IIPR, Kanpur. Morphological, biochemical and yield parameters were recoded periodically. Result: Based on the reaction of pigeon pea genotypes against the exposer of cold stress in terms of flower/pod drop and flower/pod retention, cold injury at the apical meristems and post regeneration of apical portion, the genotypes like IPA 15F, Dhule-D, JBT46/27, IPACT-6, IPACT-14, IPAC-1-17, IPACT-68, IPACT-22 showed greater than 90% flower/pod drop and retained only 0-10% flowers/pods, greater than 90% apical damage and less than 10% recovery of apical portion and were considered highly sensitive to cold stress. Genotypes namely MA-3, IPA 9F, ICP 15-9-1, VKG 27/161, H-26, ICPL 7035, LRG-30, PBT/SSL 2/73, KPL 1034-31, IPA 15-15, KPL 34, ICP 2073, IPACT-5, IPAB 10-66, IPACT-10, IPACT-11, IPAHT-26, IPACT-15, IPAD 2-8, IPACT-16, IPAD-8, IPACT-17, IPAHT-43, IPACT-21 showed greater than 80% flower/pod drop and retained 10-20% flower/pods, greater than 80%apical damage and less than 20% recovery of apical portion and considered moderately susceptible to cold stress. Genotypes NDA-2, MAL-13, ICP-2275, IPACT-2 showed around 20-40% flower/pod drop and have retained 60-80% flowers/pods, less than 20% apical damage and greater than 80% recovery of apical portion were considered as the highly tolerant to cold stress. The nitrogen balance index, chlorophyll and flavonols showed higher values in tolerant group whereas lower in susceptible group. The average yield/plant of pigeon pea genotypes tolerant to cold stress is considerably higher than the susceptible group of pigeon pea genotypes.
Health-promoting effects of glucosinolates and their breakdown products
Authors:   School of Food Science and Environmental Health, Technological University Dublin - City Campus, Ireland, O'Grady Ella , Pileckaite Greta ,   School of Food Science and Environmental Health, Technological University Dublin - City Campus, Ireland, Gilheany Almha ,   School of Food Science and Environmental Health, Technological University Dublin - City Campus, Ireland, Kucana Endrita ,   School of Food Science and Environmental Health, Technological University Dublin - City Campus, Ireland, Jaiswal Swarna ,   School of Food Science and Environmental Health, Technological University Dublin - City Campus, Ireland,   Environmental Sustainability and Health Institute, Technological University Dublin - City Campus, Ireland, Jaiswal Amit K. ,   School of Food Science and Environmental Health, Technological University Dublin - City Campus, Ireland,   Environmental Sustainability and Health Institute, Technological University Dublin - City Campus, Ireland
Published: September 2022

Glucosinolates (GLs) are a large group of secondary metabolites which are found in cruciferous plants such as broccoli, cabbage, and kale and contain nutritional and physiological active properties. Several factors affect composition levels of glucosinolates such as storage conditions, methods of consuming vegetables as well as agricultural and environmental factors. When cruciferous vegetables are consumed raw, the myrosinase enzyme found in these plants hydrolyzes the GLs in the proximal gastrointestinal tract to produce a variety of metabolites such as isothiocyanates, nitriles, oxazolidine-2-thiones, and indole-3-carbinols. Myrosinase is inactivated when cruciferous vegetables are cooked before consumption, and GLs transport to the colon, where they are hydrolyzed by the intestinal microbiota. There are many potential health effects of GLs such as antimicrobial, antioxidant, anti-inflammatory and anticarcinogenic activity of GLs. This chapter highlights the natural source of glucosinolates, absorption, the impact of various conditions on their bioavailability as well as their various health benefits.
Usos de la voz “maya” y reivindicación identitaria en una carta inédita en lengua maya yucateca del siglo XVI
Authors:   Ecole des Hautes Etudes en Sciences Sociales, Paris, France, Cunill Caroline
Published: September 2022

At the beginning of the 1580s, some Maya caciques of Yucatan sent to King Philip II a letter asking him the future bishop of the province to be Franciscan and a group of religious from the same Order to be sent to the peninsula in order to consolidate the evangelization of Native people. The letter was written in Yucatec maya and was translated into Castilian by the interpreter Juan Ruiz de la Vega. The record, which remains unpublished until today, completes the restricted corpus of sixteenth century texts written in Yucatec maya and, for that same reason, it has an exceptional historical value. The present article offers a linguistic and philological analysis of both the maya text and its translation. It aims at highlighting that the term “maya” was used in the letter to emphasize the native linguistic and cultural identity. We also demonstrate that the interpreter intended to minimize the expression of this revendication in its translation.
Therapeutic effect of explosive-synthesis nanodiamonds in cobalt-induced dermatitis
Authors:   Prof. V. F. Voino-Yasenetsky Krasnoyarsk State Medical University, Vasilyeva E.Yu. , Karacheva Yu.V. ,   Prof. V. F. Voino-Yasenetsky Krasnoyarsk State Medical University, Puzyr A.P. ,   Siberian Branch of Russian Academy of Science, Bondar V.S. ,   Siberian Branch of Russian Academy of Science
Published: September 2022

The aim of the research. To evaluate the therapeutic eff ect of modifi ed nanodiamonds (MND) of explosive synthesis for treatment of allergic contact dermatitis induced by cobalt ions. Material and methods. Th e study was performed on guinea pigs. Th e animals were divided into 3 groups (6 animals in each group). Allergic contact dermatitis was initiated using 2% aqueous solution of cobalt nitrate applied to the animals’ skin for 14 days according to the common procedure. For allergic contact dermatitis treatment, glycerol and MND suspension with the nanoparticle concentration of 5g · l-1 prepared in glycerol were used. MND with high colloidal stability in water suspensions and the average nanoparticle cluster size of d50 = 50nm was used in the work. Th e animals of group I were controls: aft er allergic contact dermatitis development, their skin was not treated by any means for 7 days. Th e animals in groups II and III were experimental: aft er allergic contact dermatitis initiation, their skin was treated for 7 days using glycerol and MND suspension, respectively. Upon experiment completion, biopsy of skin sample was performed on all animals for histological and spectral examination. The content of cobalt in skin samples was determined through atomic adsorption spectroscopy. Results. The results of histological and morphometric analysis indicate that, in the case with dermatitis modelled in guinea pigs using cobalt ions, treatment of the animals’ skin with MND suspension reduces allergic inflammation intensity. Th e therapeutic effect of MND is caused by adsorption of cobalt ions onto nanoparticles and their subsequent elimination from the skin, which complies with the atomic adsorption spectroscopy data. Conclusion. Th e prospects of MND as a new therapeutic agent for binding and elimination of chemical allergens (particularly, cobalt ions inducing the allergic contact dermatitis development) are discussed.
Modern methods for prediction and diagnosis of postpartum bleeding
Authors:   Chita State Medical Academy, Mochalova M.N. , Sidorkina A.G. ,   Chita State Medical Academy, Mudrov V.A. ,   Chita State Medical Academy
Published: September 2022

Abstract. In the Russian Federation, approximately 5 % of births are complicated by postpartum haemorrhage. Postpartum haemorrhage is the leading cause of maternal morbidity and mortality worldwide. Most maternal deaths associated with bleeding can be prevented. Identifi cation of risk factors, methods of prediction and timely recognition of postpartum haemorrhage remain serious problems in obstetrics. The aim of the research was to analyse modern methods for prediction and diagnosis of postpartum haemorrhage. Material and methods. Th e aim of the research was achieved through the analytical method: a detailed systematic analysis of modern Russian and foreign literature on methods for predicting and diagnosing postpartum hemorrhage was carried out. The study used such databases as e-library, Scopus, PubMed, MEDLINE, ScienceDirect, Cochrane Library and FIIP for search of publications dated January 2015 to December 2021. Results. Postpartum haemorrhage, despite the widespread implementation of clinical guidelines in obstetric practice, remains a serious medical problem. Modern prediction methods are based on risk stratification and do not provide for accurate prediction of development of such a formidable complication. Today, a method for automatic monitoring of postpartum uterus volume for early diagnosis of postpartum haemorrhage has been developed. However, such a technology has only been implemented in a number of scientific studies. Conclusion. Methods for diagnosing postpartum haemorrhage are diverse and each of them has its own advantages and disadvantages, i.e. they can only be effective when used in combination. Also, an important role in prediction and timely diagnosis of postpartum haemorrhage is played by the level of training of medical personnel and their teamwork skill.
Diagnosis of the olfactory function in patients with chronic rhinosinusitis: a literature review
Authors:   Prof. V. F. Voino-Yasenetsky Krasnoyarsk State Medical University, Vakhrushev S.G. , Smbatyan A.S. ,   Prof. V. F. Voino-Yasenetsky Krasnoyarsk State Medical University, Korneva J.S. ,   Prof. V. F. Voino-Yasenetsky Krasnoyarsk State Medical University
Published: September 2022

The aim of this review article is a comprehensive systematic review of peer-reviewed literature data on the methods for olfactory dysfunction diagnosis in patients with chronic rhinosinusitis with consideration for anatomy and pathomorphology. Additionally, we have assessed the reliability and informative value of various methods. The search was carried out in PubMed, Web of Science and Google Scholar databases using the following keywords: “smell” AND “rhinosinusitis” OR “polyps”. As a rule, the presented methods of olfactory function diagnosis for patients with chronic rhinosinusitis only allow determining of quantitative disorders. It is required to select a universal diagnostic method which will make it possible to determine the location of the olfactory nerve lesion, the quantitative and qualitative impairment of the function taking into account the olfactory nerve fatigue and the time of adaptation.
Influence of alcohol on prenatal development of the foetus
Authors:   Bashkir State Medical University, Ziganshin A.M. , Yashchuk A.G. ,   Bashkir State Medical University, Mulykov A.R. ,   Bashkir State Medical University, Omarov M.A. ,   Bashkir State Medical University, Khisamova N.R. ,   Bashkir State Medical University
Published: September 2022

Th e aim of the research. To review the main factors of the adverse eff ects of alcohol on the body of the mother and the fetus. Th e review was compiled using the following databases: Scopus, MedLine, the Cochrane Library, Cyberleninka, RSCI, etc. Material and methods. The analysis of Russian and foreign scientifi c literature used the following keywords: “fetal alcoholic syndrome”, “fetal alcohol spectrum disorder”, “partial alcoholic fetal syndrome”, “alcohol-related disorder”, “neururoperative disorder associated with the prenatal effects of alcohol”, “congenital developmental defects associated with alcohol”. Th e material was compiled from the references of review articles and the selection was carried out based on the scientific value with formation of the fi nal list of literature according to the relevance of the analysed material. Results. The review presents the results of studies confi rming the adverse eff ects of alcohol on the mother’s and foetus’s organism, indicating the need to continue research to develop diagnostic criteria necessary for the diagnosis of fetal alcohol syndrome. The negative effect of alcohol intake on the fetus during intrauterine development manifesting in future neurological and behavioural disorders, mental and physical development delay, congenital defects and the stigma of facial skull dysembryogenesis has been proved. Conclusion. Numerous studies on the effect of alcohol on the mother’s and foetus’s body indicate a negative impact on the latter exerted by alcohol intake in the period of intrauterine development. All this confirms the need to improve the quality of medical care for pregnant women, the need to carry out sanitary and educational events for general practitioners, obstetricians-gynaecologists and medical staff in medical prevention and/or health facilities, as well as in families and the society as a whole.
Molecular effects of plasma acid on the ovarian endometrioma capsule tissue
Authors:   Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Salmin V.V. , Perevertov T.A. ,   Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Muradyan G.A. ,   Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Gudkova E.S. ,   St. Petersburg State Pediatric Medical University, Epova A.S. ,   Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Kutyakov V.A. ,   Krasnoyarsk Regional Bureau of Forensic Medicine, Lychkovskaya E.V. ,   Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Chekisheva T.N. ,   Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Malinovskaya N.A. ,   Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Medvedeva N.N. ,   Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Makarenko T.A. ,   Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Salmina A.B. ,   Scientific Center of Neurology
Published: September 2022

The aim of the research. To study the molecular effects of water treated with spark-discharge plasma on tissues of the cyst wall of the ovarian endometrium in vitro. Material and methods. Tissues of the ovarian endometrial cyst capsule obtained during the surgical treatment of women through laparoscopic access were incubated in various modes in plasma acid, ethanol and physiological solution at room temperature. Plasma acid was produced by treating water for injection with spark-discharge plasma to a decrease in pH<2.0. Aft er the immunohistochemical study of the preparations, a comparative analysis of ablative and apoptogenic action via TUNEL was performed, as well as analysis of proangiogenic action (VEGFA), endothelial progenitor cells (CD133), protein damage (NT), DNA damage (8-OHdG) and proliferation activity (Ki67) of different treatment methods from the standpoint of potential plasma acid efficacy for sclerotherapy of ovarian endometrioma as compared to standard sclerosant: ethanol. Results. Th e study has demonstrated a more pronounced ablation and pre-apoptogenic effect of plasma acid on tissues of the ovarian endometrium capsule than ethanol. In addition, a decrease in neoangiogenesis and protein damage from active forms of nitrogen (protective action) compared to ethanol was shown. Conclusion. Water treated with spark-discharge plasma can be considered an eff ective alternative to ethanol for ovarian endometrioma sclerotherapy. The sequential action of plasma acid and ethanol increases the sclerosing action of ethanol.
A personalised approach to early diagnosis of the fulminant form of acute necrotising pancreatitis
Authors:   Private Healthcare Institution “Clinical Hospital” Russian Railways-Medicine of Krasnoyarsk, Gulikyan G.N. , Kozlov V.V. ,   First Moscow State Medical University named aft er I.M.Sechenova
Published: September 2022

The aim of the research. To develop an individual approach to diagnosis of the fulminant form of acute pancreatitis based on laboratory and instrumental research methods. Material and methods. Th e retrospective phase of the study (2016-2018) enrolled 31 patients diagnosed with severe acute pancreatitis (SAP) – the control group. These patients underwent analysis of the results of surgical treatment in order to determine the factors of adverse outcome of the disease. On this basis, a special category of patients was identified, requiring changes in existing diagnostics and surgical tactics depending on the course of the disease. At the prospective stage (2018-2020), a total of 27 patients diagnosed with SAP (the main group) were included. Results. For these patients, we introduced an individualised approach to diagnosis and performed comparative analysis of its effectiveness. The comparative analysis of both groups was carried out based on the main indicators of the patients’ initial condition. Th e distribution of patients between the compared groups had no statistical difference in the gender composition (χ 2 = 0.141, p> 0.05). Th e age of patients ranged from 24 to 83 years. The average age was 44.3 ± 12.6 years in the control group and 43.7 ± 14.4 years in the main group (Student’s t-test = 0.7, p > 0.05). No statistically significant differences were revealed between groups in each age category. Conclusion. In our study on patients with fulminant progression, we emphasised a combination of additional attributes. Th e analysis has revealed statistically significant differences between the “fulminant” and the “typical” progression in the occurrence rate of the combination of attributes.
Free tissue transfer for lower extremity trauma in the pediatric patient
Authors: Othman Sammy , Knobel Denis
Published: September 2022

Aim: The utilization of free-tissue transfer secondary to traumatic lower extremity defects in the pediatric population is scarcely described. Factors include microsurgeon inexperience, inadequate center resources, and fear of historically described poor surgical outcomes. The aim of this study is to investigate more recent articles describing free-flap microsurgical reconstruction for these defects. Methods: A systematic review of the literature was conducted through the online databases PubMed, Embase, and Web of Science, examining for articles with at least 20 subjects utilizing free-tissue transfer for soft-tissue defects of the pediatric (aged 18 and younger) lower extremity following traumatic etiology since 2005. Outcomes included flap failure, return to the operating room, and functional status, where available. Results: Seven studies were deemed appropriate for inclusion, with a total of 243 flaps included. Motor vehicle and motorcycle accidents were greater than 75% of total etiology. Most defects involved the foot or ankle (65.1%). In total, perforator flaps compromised the majority of flaps (54%), with the most common being the anterolateral thigh, the scapular/parascapular, and deep inferior epigastric flaps. Less common perforators included the groin flap, tensor fascia lata, radial forearm, lateral arm, and thoracodorsal perforator flap. Muscle-based flaps were less common (46%), with the latissimus dorsi and rectus muscle flaps composing the majority. The most commonly used recipient vessel was the anterior tibialis (49.5%) and posterior tibialis vessels (45.3%). Most studies performed reconstruction within 7-10 days of presentation. There was a cumulative 6.5% flap failure rate. Conclusion: Free tissue transfer for pediatric lower extremity trauma is an important tool that likely leads to powerful outcomes. Recent trends indicate increasing usage of perforator flaps. This study shows that based on existing data, free flap utilization for pediatric patients is an adequate modality for repair, and may warrant greater consideration moving forward.
Tenofovir disoproxil fumarate is not associated with a lower risk of hepatocellular carcinoma compared to entecavir in patients with chronic hepatitis B
Authors: Lee Hye Won
Published: September 2022

A paper published several years ago suggested that tenofovir disoproxil fumarate (TDF) was superior to entecavir (ETV) for reducing the risk of hepatocellular carcinoma (HCC). Since then, many observational studies have been conducted comparing TDF and ETV. Many studies in Asia demonstrated similar HCC risks between ETV and TDF groups. Similarly, recent studies involving Caucasian and European did not observe any differences in HCC risk between these groups. In this article, we briefly review studies that compared the incidence rates of HCC between ETV and TDF and discuss potential reasons for the discrepant results.
The complex relationship between multiple drug resistance and the tumor pH gradient: a review
Authors: Koltai Tomas
Published: September 2022

Multiple drug resistance (MDR) is the tumor’s way of escaping the cytotoxic effects of various unrelated chemotherapeutic drugs. It can be either innate or acquired. MDR represents the end of the therapeutic pathway, and it practically leaves no treatment alternatives. Reversing MDR is an unfulfilled goal, despite the important recent advances in cancer research. MDR, the main cause of death in cancer patients, is a multi-factorial development, and most of its known causes have been thoroughly discussed in the literature. However, there is one aspect that has not received adequate consideration - intracellular alkalosis - which is part of wider pH deregulation where the pH gradient is inverted, meaning that extracellular pH is decreased and intracellular pH increased. This situation interacts with MDR and with the proteins involved, such as P-gp, breast cancer resistance protein, and multidrug associated resistance protein 1. However, there are also situations in which these proteins play no role at all, and where pH takes the lead. This is the case in ion trapping. Reversing the pH gradient to normal can be an important contribution to managing MDR. The drugs to manipulate pH exist, and most of them are FDA approved and in clinical use for other purposes. Furthermore, they have low or no toxicity and are inexpensive compared with any chemotherapeutic treatment. Repurposing these drugs and combining them in a reasonable fashion is one of the points proposed in this paper, which discusses the relationship between cancer’s peculiar pH and MDR.
Towards responsible ctDNA-based multi-cancer screening: a preliminary exploration and discussion of ethically relevant aspects
Authors: Dondorp Wybo
Published: September 2022

While testing for easily accessible biomarkers in the circulation (“liquid biopsy”) has found its way to clinical cancer care, a further expected development is its use as a “universal” early detection test in population screening for cancer. A promising marker for such screening is circulating cell-free fragments of tumor DNA, shed into the circulation during tumor cell turnover. Several blood-based “multicancer early detection (MCED) tests” have recently been developed - but still need validation in large-scale studies involving non-patient populations. In this paper, we proactively explore the ethical aspects of this development. We refer to an often quoted synthesis of the internationally accepted framework of principles for responsible screening as first drawn up for the World Health Organisation (WHO) by Wilson and Junger 50 years ago and further developed and fine-tuned ever since. As our analysis suggests, some specific ethical issues and concerns about potential MCED screening connect to the fact that cancer is not just one disease. As a consequence, not all findings will have the same clinical utility. We discuss this against the background of earlier debates pertaining to broad scope forms of screening in other contexts, specifically newborn and reproductive genetic screening. We highlight the guidance provided by some of the criteria from the screening framework that seems most relevant in this connection: the need for screening objectives to be defined at the outset, the need for mechanisms to minimize potential risks, and the requirement that, for those participating in the screening, the overall benefits outweigh the harm.
Aviation attacks based on ILS and VOR vulnerabilities
Authors: Choudhary Gaurav , Sihag Vikas , Gupta Shristi , Shandilya Shishir Kumar
Published: September 2022

Aim: As the aviation industry grows more digital and reliant on wireless technology, it has grown more appealing to cyber criminals, including nation-state actors and terrorists. Vulnerabilities in a wide range of networked devices and (sub)systems, as well as their implementations and design defects, can be used to carry out malicious operations. The purpose of this study is to provide a comprehensive survey threats on aviation communication models. Methods: We describe an overview of aviation threat model and attacks. A detailed taxonomy predicated on security vulnerability is presented. Further, this paper discusses the research aspects and challenges to be taken care of in aviation security and communication Finally, we conclude with a summary of the current state of threats and their consequences for widely-used aviation models. Results: The main findings of this study is to introduce fundamental security vulnerabilities of aviation model and classify into categories to efficiently analyze them. Vulnerabilities of VOR, ILS systems and their impact are also discussed. Moreover, we describe and assess mitigation systems to defense these attacks. Conclusion: We conclude that the aviation system is still exposed to various attacks. We examine key technological challenges that have been serving as a deterrent to adopting more secure alternative approaches, as well as research avenues where further progress is needed.
PERBANDINGAN TANAMAN JAGUNG DAN KACANG HIJAU PADA MUSIM KEKERINGAN DI GROBOGAN
Authors: Irawati Etik , Fianti Fianti , Nurbaiti Upik
Published: September 2022

Almost every year, most of Grobogan Regency experiences drought which can affect various fields including agriculture, where some of the people are farmers. This article aims to analyze the comparison of the secondary crops of maize and green beans during the drought season in the villages of Banjardowo, Plosorejo, and Mayahan, Grobogan Regency. This study used survey research involving 20 respondents (farmers) from the three villages. Data collection techniques, namely, observation, interviews, respondent questionnaires and documentation. The results of the interview showed that the interviewee planted green beans as a staple crop in both the rice-paddy-secondary crops and the rice-crops-bero cropping pattern. Cultivating green beans in the rice-crops-bero pattern, the farmers of the three villages planted them on broken land (nelo: Java) because of the high level of drought. The results from 20 respondents were seen from 6 aspects: 1) suitability of plants in the dry season. 2) Planting on the ground that is broken (Nelo: Java). 3) relatively water efficient. 4) High Income. 5) Pest resistance. 6) Abbreviations of the harvest period, namely the average yield of green bean plants is 87.04% while corn is 52.04%. The conclusion of this research is that green beans are a suitable alternative crop to be planted in the dry season.
IMPLEMENTASI PROGRAM PENGELOLAAN DAN PENATAAN HUTAN KOTA PATRIOT BINA BANGSA DI KOTA BEKASI
Authors: Chealsiyana Hayumi Febyan , Sugiarti Cucu , Atthahara Haura
Published: September 2022

The function of urban forest can reduce the impact of the greenhouse effect, while on a micro level, it is to eliminate the negative impact of urban development and economic development. The purpose of the existence of urban forests is to eliminate the imbalance of urban ecosystems as a result of economic development and population growth that tends to be green open space. Thus, urban forests can endanger or at least be able to maintain ecosystem balance, temperature changes, air pollution, air pollution, decreased ground air levels and the danger of flooding. Several objectives are based on the discipline of Government Science that uses Rippley and Franklin's program policy implementation model, including to understand and understand the level of censorship, at any time and to understand smooth and no problems in management and arrangement, and to see and understand the performance of the apparatus in management. and the arrangement of the Patriot Bina Bangsa City Forest. The research technique used in this research is literature study and field studies with observation, interviews, and documentation. This type of research is qualitative using descriptive analysis method with a theoretical basis to provide an overview of the research background and as material for the discussion of research results. Based on the results of research that applies the implementation theory of the Rippley and Franklin model, it shows that the implementation in the management of the Patriot Bina Bangsa City Forest has not been successful, and needs evaluation for the future.
PERANCANGAN ALAT MONITORING KUALITAS UDARA SECARA REAL-TIME DI KAWASAN PASAR BUNGO
Authors: Lubis Mutia Hariza , Nurbaiti Upik , Fianti Fianti
Published: September 2022

The market area in Bungo Regency is an area with community activities and a high number of vehicles so that it has an impact on the air quality around the area. This study aims to design a monitoring tool as a cost-effective facility in order to monitor air quality as a first step to minimize air pollution in the Bungo market area. Air quality is assess through temperature and humidity measured using the DHT11 sensor, smoke levels in the air are measured using the MQ2 sensor, and light intensity is measured using the LDR module.
EKSTRAKSI DAN UJI POTENSI ANTIOKSIDAN DARI SENYAWA POLIFENOL JANTUNG PISANG CAVENDIS (Cavendis varadishii) YANG DIFERMENTASI ASAL PT. NUSANTARA TROPICAL FARM (NTF) LAMPUNG
Authors: Kurniawati N. , Khasbullah F. , Priyadi Priyadi
Published: September 2022

Banana blossom is waste, especially in PT. Nutrition Tropical Farm (NTF) as the largest bananaexporter in Lampung. Cavendis banana blossom in PT. NTF cannot be consumed like some other particular banana blossoms. Cavendis banana blossom from the company has a bitter tastebecause it contains high polyphenol compounds. High polyphenol compounds in the banana blossom can be acquired through an extraction process that furthermore can be used as antioxidants. By utilizing the polyphenol compounds in the banana blossom, it is possible to utilize and optimize the use value and economic value of the waste or by products of banana plant cultivation. The purposes of this study are 1) Increasing the acquisition of polyphenol extracts in Cavendis banana blossom extract from PT. NTF, 2) antioxidant activity by polyphenol compounds extract of Cavendis banana blossom from PT. Nusantara Tropical Farm. The result shows that spontaneous fermentation of the banana blossom affects the lignocellulose component and the acquisition of bioactive compounds. The highest yield of bioactive components extracts produced from 3 th day incubation for total polyphenols  (982 mg/100mg), anthocyanin (25.34 mg/100 mg) and the highest antioxidant activity of catechin (37.74%) produced form 3 th day incubation.
PERTUMBUHAN DAN HASIL KEDELAI EDAMAME (Glycine max (L.) Merr.) DENGAN APLIKASI PUPUK ORGANIK GUANO DI TANAH TUKUNGAN
Authors: Saputra Riza Adrianoor , Jumar Jumar , Hayatullah Muhammad
Published: September 2022

Soybean is the third most consumed staple food after rice and corn. The need for soybeans continues to increase accompanied by an increase in population and the need for raw materials for the food processing industry such as tofu, tempeh, soy sauce, soy milk, etc. One type of soy that is harvested fresh is edamame soybeans. The number of farmers who grow edamame soybeans in South Kalimantan is still relatively few. This has the potential to be developed. However, the problem is that soybean productivity in South Kalimantan is still low. This is due to the low level of soil fertility, such as tukungan soil. Tukungan soil is a mound of soil in the middle of rice fields that farmers have deliberately made so that they can plant plants that do not like excess water. The use of guano organic fertilizer in edamame soybean cultivation can be a solution in overcoming soil fertility problems in tukungan soil. The purpose of this study was to determine the best dosage of guano organic fertilizer for the growth and yield of edamame soybeans in tukungan soil. The research was carried out from November 2019 to February 2020, at the Greenhouse of the Agroecotechnology Department, Faculty of Agriculture, Universitas Lambung Mangkurat, Banjarbaru. This study used one factor completely randomized design. The factors studied were the dosage of guano organic fertilizer (K) which consisted of five levels, namely: k0 = 0 ton/ha, k1 = 10 ton/ha, k2 = 20 ton/ha, k3 = 30 ton/ha and k4 = 40 ton/ha. The results showed that the dose of 30 ton/ha of guano organic fertilizer was the best dose in increasing plant weight and pod weight of edamame soybean, respectively 41.93% and 67.62% compared to the control treatment.