bluuebunny/crossref_metadata_2025 huggingface dataset:
Postnatal cytomegalovirus infection and its effect on hearing and neurodevelopmental outcomes among infants aged 3–10 months: A cohort study in Eastern Uganda
Authors: Okalany Noela Regina Akwi , Mukunya David , Olupot-Olupot Peter , Chebet Martin , Okello Francis , Weeks Andrew D. , Bisso Fred , Tylleskär Thorkild , Burgoine Kathy , Engebretsen Ingunn Marie Stadskleiv
Published: February 2025

Background

Hearing impairment and neurodevelopmental disorders pose a significant global health burden in children. The link between postnatal cytomegalovirus (CMV) infection and these outcomes remains unclear. This study explored the association of postnatal CMV infection with hearing and neurodevelopmental outcomes in term infants aged 3 to 10 months.

Methods

This was a cohort sub-study within the BabyGel cluster randomised trial in Eastern Uganda. From 1265 term infants screened for CMV, 219 were negative at birth but positive at 3 months, and were age-matched with 219 CMV-negative controls. CMV status was determined by PCR screening of saliva samples, with positive results confirmed using urine samples (Chai Open qPCR, Santa Clara, CA). From the established cohort, 424 infants were successfully followed up between 3 to 10 months of age. Clinical assessments included neurodevelopmental evaluation using the Malawi Developmental Assessment Tool, the Hammersmith Infant Neurological Examination, and hearing screening using Otoacoustic Emission testing (Otoport Lite, Otodynamics Limited). Statistical analyses were performed using descriptive statistics, chi-square tests and log binomial regression models with Stata 18.

Results

Of the 424 infants included in the study, 206 were postnatal CMV-infected and 218 were uninfected. Neurodevelopmental assessments indicated no differences between postnatal CMV-infected infants and uninfected groups (ARR 0.88, 95% CI [0.67, 1.15], p = 0.346). Hearing screening revealed a 1.99-fold increased risk of a positive result for postnatal CMV-infected infants compared to uninfected infants (67/106 vs. 39/106, 95% CI [1.27, 3.12], p = 0.003).

Conclusion

Postnatal CMV infection was associated with more positive hearing screenings, though no significant differences in neurodevelopmental outcomes were observed in early infancy. Exploration into the feasibility of incorporating hearing and CMV screening into routine care will play a vital role in early identification and intervention, improving the management of both hearing and CMV-related conditions in resource-limited settings.
Major factors influencing student engagement in Ethiopian higher education institutions: Evidence from one institution
Authors: Faro Mekonnen Haile , Gutu Tariku Sime , Hunde Adula Bekele
Published: February 2025

This study investigates factors influencing student engagement in Ethiopian higher education, focusing on self-efficacy, teacher support, and technology support at Mattu University. A cross-sectional survey design was employed; involving 620 undergraduate students selected using stratified sampling. Data were collected through structured questionnaires and analyzed using Structural Equation Modeling (SEM) to assess the impact of these variables on student engagement. The findings reveal that teacher support, technology support, and self-efficacy collectively explain 69% of the variance in student engagement, with teacher support identified as the strongest predictor. The results highlight the importance of supportive teacher-student relationships, accessible digital resources, and students’ confidence in their academic abilities for fostering engagement. The study underscores the need for improved teacher preparation, diverse instructional strategies, and enhanced access to digital resources. These findings offer practical recommendations for policymakers and educational institutions in Ethiopia to create more engaging learning environments, ultimately enhancing academic success and retention in higher education.
Exploring short-term memory and listening effort in two-talker conversations: The influence of soft and moderate background noise
Authors: Mohanathasan Chinthusa , Ermert Cosima A. , Fels Janina , Kuhlen Torsten W. , Schlittmeier Sabine J.
Published: February 2025

Listening to conversations and remembering their content is a highly demanding task, especially in noisy environments. Previous research has mainly focused on short-term memory using simple cognitive tasks with unrelated words or digits. The present study investigates the listeners’ short-term memory and listening effort in conversations under different listening conditions, with and without soft or moderate noise. To this end, participants were administered a dual-task paradigm, including a primary listening task, in which conversations between two talkers were presented, and an unrelated secondary task. In Experiment 1, this secondary task was a visual number-judgment task, whereas in Experiments 2 and 3, it was a vibrotactile pattern recognition task. All experiments were conducted in a quiet environment or under continuous broadband noise. For the latter, the signal-to-noise ratio in Experiments 1 and 2 was +10 dB (soft-noise condition), while in Experiment 3 it was -3 dB (moderate-noise condition). In Experiments 1 and 2, short-term memory of running speech and listening effort were unaffected by soft-noise listening conditions. In Experiment 3, however, the moderate-noise listening condition impaired performance in the primary listening task, while performance in the vibrotactile secondary task was unaffected. This pattern of results could suggest that the moderate-noise listening condition, with a signal-to-noise ratio of -3 dB, required increased listening effort compared to the soft-noise and quiet listening conditions. These findings indicate that listening situations with moderate noise can reduce short-term memory of heard conversational content and increase listening effort, even when the speech signals remain highly intelligible.
Impact of human body shape on free convection heat transfer
Authors: Viswanathan Shri H. , Joshi Ankit , Bartels Lyle , Sadeghi Kambiz , Vanos Jennifer K. , Rykaczewski Konrad
Published: February 2025

Understanding the thermal comfort and safety of diverse populations within indoor settings requires a quantitative understanding of the primary heat exchange pathways between occupants and their surroundings: radiation and free convection. Thus far, however, free convective heat transfer coefficients have only been determined for the average Western adult. To this end, we investigated how variation in body shape impacts free convection heat transfer using an experimentally validated numerical model. The multiphysics model was compared against experiments conducted using the thermal manikin ANDI ("Advanced Newton Dynamic Instrument") in a climate-controlled enclosure across five air-to-skin temperature differences ranging from 4.9 to 13.9°C. The difference between measured and simulated heat fluxes for the whole body, and per anatomical region, was typically <5%, occasionally reaching 15–20%, for some body regions due to physical features not modeled in the virtual ANDI model. Using the validated model, we simulated free convection around a family, or diverse group, of virtual manikins representing the 1st to 99th percentile body mass index (BMI) and height variation in the United States adult population. Our results show that the free convection heat transfer coefficient is independent of human sex and height but decreases slightly with increased BMI. However, the variation from the average manikin in the whole body and regional free convection coefficients with BMI was small, not exceeding 8% and 16%, respectively. Furthermore, our regression coefficients and exponents can be derived from the theorical correlation for free turbulent convection from a vertical plate, which also explains the observed independence of the heat transfer coefficient from the manikins’ height. Overall, these findings demonstrate the general applicability of using an average body shape in indoor thermal audits and/or overheating risk assessments to understand thermal comfort and heat stress. The results and valid application of the model support critical insights for human health, productivity, and well-being connected to heat and cooling in buildings.
Revalidation of Solanum sanfurgoi (Solanaceae), an endemic species of central Chile
Authors: Almendras Diego , Villalobos Macarena , Perez Surimana , Ciudad Teresa , L. Moyano Nodora
Published: February 2025

As part of a collaborative initiative focused on studying the local biodiversity of the Mataquito River in central Chile, rediscovery and revalidation of Solanum sanfurgoi is presented. This species was previously known only from a single specimen collected in 1895 and was considered a synonym of Solanum grandidentatum since 2023. An updated description of the species is provided, along with an illustration and a key for the Morelloid clade in central Chile.
Una especie nueva del género neotropical Malanea (Rubiaceae, Guettardeae) de la región Amazónica venezolana
Authors: Amaya Worm Alix , Leython Chacón Sirli , Raymúndez María , Torrecilla Pedro , Manara † Bruno
Published: February 2025

Se describe e ilustra Malanea maigualidensis, una nueva especie de la familia Rubiaceae que crece en la Sierra de Maigualida, el sistema montañoso de roca no sedimentaria más largo y ancho de la Amazonia venezolana. Malanea maigualidensis es similar a M. duckei y M. sarmentosa pero se puede distinguir por su densa pubescencia tomentosa blanco-dorada en la cara abaxial de las hojas y en el lado externo de las estípulas; limbo del cáliz lobulado, lóbulos desiguales de 1-1,5 mm y lóbulos de la corola 2,5-3 mm. En contraste, M. duckei se caracteriza por tener estípulas de 7-8 x 4-5 mm; cáliz subtruncado y tubo de la corola de 2 mm; M. sarmentosa, por su parte, tiene el limbo del cáliz truncado y la pubescencia en el envés de las hojas, ramas, pedúnculo y raquis de la inflorescencia es densamente tomentosa marrón-rojiza-ferrugínea. Se incluye una clave para diferenciar algunas especies de Malanea que crecen en el Sur de Venezuela y Brasil.
Current scenario of insect pests on jackfruit in Tamil Nadu
Authors: Kanna S S , Rhamya S K , Rithiga M , Sabareesh V , Premalatha K , Kavitha K , Rajadurai K R
Published: February 2025

Studies on the seasonal incidence of pests and natural enemies in different Jackfruit cultivars revealed the presence of various pests and predators in the Jackfruit ecosystem. The major pests identified included the fruit and shoot borer (SFB), stem borer, mealybug, whitefly, spittle bug, bud weevil and fruit fly. At the same time, predatory coccinellid beetles were the key natural enemies. The fruit and shoot borer (8.92%), stem borer (0.21%), mealybugs (1.48%), bud weevil (19.28%) and whiteflies (17.78%) were less in Muttam varikkai followed by Palur 1- SFB (27.57%), stem borer (1.35%), mealybug (1.14%), whiteflies (18.21%) and bud weevil (17.92%). The Jackfruit cultivar, Muthandikuppam, was found to be more susceptible to insect pests, which recorded SFB (37.85%), mealybugs (2.42%), whitefly (35.50%) and bud weevil (26.42%). The chrysopa and coccinellids population was high in AH2 Muthandikuppam (4.00 and 17.68/tree) followed by AH15 Muthandikuppam (3.21 and 17.17/tree). Comparatively, the spiders were found high in Pechiparai 1 (11.78/tree), but in AH2 Muthandikuppam it was 7.35 per tree. The SFB, stem borer, mealybugs, whiteflies and bud weevil were more during hot weather and were positively correlated with maximum and minimum temperature. In contrast, they are negatively correlated with other weather parameters, viz., rainfall, wind speed and relative humidity. The SFB incidence was recorded as high during maximum temperature (0.479) with high wind speed (0.502) and minimum temperature (0.577). The population of coccinellids beetles increased with maximum temperature (0.71), minimum temperature (0.706), high wind speed (0.312) and relative humidity (0.514).
Morphological, physiological and biochemical trait analysis of maize inbreds under drought conditions
Authors: Priyanandhini L , Kalarani M K , Senthil A , Senthil N , Pazhanivelan S , Karthikeyan R , Umapathi M , Vanitha G
Published: February 2025

Maize (Zea mays L.) is a crucial cereal crop that is highly sensitive to drought, which disrupts its morphological, physiological and biochemical traits, impairing photoassimilate allocation. A 2-year field experiment was conducted to assess drought tolerance mechanisms in 6 maize inbred lines—CBM-DL 38, CBM-DL 111, CBM-DL 238, CBM-DL 448, CBM-DL 360 and UMI 1200—by evaluating morphological, physiological, biochemical changes as well as carbohydrate assimilation during sensitive growth stages. Drought stress was applied at different growth stages and observations were recorded 10 days after stress initiation. Drought stress significantly affected growth stages, canopy traits, carbon assimilation and yields. The chlorophyll index decreased by 17–23%, the vegetative index by 33–36% and chlorophyll fluorescence by 47–48%. Meanwhile, the leaf angle increased to 25–30° and the flagging point ratio was reduced to 0.8, resulting in 56–59% yield reduction. However, CBM-DL 38, CBM-DL 111, CBM-DL 448 and CBM-DL 360 demonstrated enhanced drought tolerance, with reduced malondialdehyde (1.5–1.8 times), increased proline (75–93%), improved antioxidant activities [catalase (52–76%), peroxidase (45–57%)] and higher leaf tissue water content (43–59%). Improved leaf architecture enhanced light captures and resource allocation, reducing oxidative damage and maintaining yields. In contrast, CBM-DL 238 and UMI 1200 showed greater reductions in cob weight and 100-grain weight (47–49%). Drought stress during 35–75 days after sowing (DAS) severely impaired photosynthesis, leading to reduced yields. Enhanced canopy traits and biochemical resilience made CBM-DL 38, CBM-DL 111, CBM-DL 448 and CBM-DL 360 more drought-tolerant.
Źródła do badań słownictwa gwar kieleckich
Authors: Cygan Stanisław
Published: February 2025

W artykule podejmuję próbę charakterystyki nowszych źródeł do badań leksyki gwarowej regionu kieleckiego. Są to zróżnicowane pod względem charakteru (typu) takie źródła, jak np.: regionalne słowniki gwarowe, a zwłaszcza wykorzystywane w mniejszym stopniu teksty literatury regionalnej, materiały prasowe, poradniki kulinarne czy książki kucharskie.
Frazeologizmy w funkcji gwarowych nazw roślin
Authors: Kulak Ilona
Published: February 2025

Artykuł pokazuje, jakie nazwy roślin funkcjonujące w gwarach należy traktować jako frazeologizmy i jaki jest stopień ich sfrazeologizowania. Zagadnienie omówiono na przykładzie 647 fitonimów zebranych w latach 2016–2017 w kilku wsiach podhalańskich. W szkicu przedstawiono klasyfikację leksemów wielowyrazowych, ukazano także związek między typami frazeologizmów odnoszących się do roślin a semantyką składników konstrukcji i motywacją zanotowanych nazw. Z przeprowadzonej analizy wynika, że wśród frazeologizmów stanowiących gwarowe określenia ziół, kwiatów czy drzew dominują metaforyczne, dwuwyrazowe związki idiomatyczne, których element nadrzędny wskazuje zwykle na podobieństwo rośliny lub jej części do innego obiektu, podrzędny natomiast wzbogaca treści podstawowe bądź informuje o innych cechach desygnatu.
Linearization in magnetoelasticity
Authors: Almi Stefano , Kružík Martin , Molchanova Anastasia
Published: February 2025

Starting from a model of nonlinear magnetoelasticity where magnetization is defined in the Eulerian configuration while elastic deformation is in the Lagrangian one, we rigorously derive a linearized model that coincides with the standard one that already appeared in the literature and where the zero-stress strain is quadratic in the magnetization.
The relation of the nonlinear and linear model is stated in terms of the Γ-convergence and convergence of minimizers.
Ecological restoration in valley area of semiarid region damaged by shallow buried coal seam mining
Authors: Chen Puhao , Wang Jianbin , Wang Haiyan
Published: February 2025

Coal seams in valley areas are shallow buried, and mining activities have a strong impact on the surface environment, so ecological restoration in this condition is very difficult. Strengthening the monitoring of ecological changes plays an important role in optimizing mining methods and ecological restoration. In this article, a valley area in the northern Shaanxi Province of China was selected as the research area, and a similar ecosystem around the study area was selected as the reference subject. The traditional remote sensing ecological index model was improved, and a new evaluation model was constructed based on the framework of Modified Remote Sensing Ecology index-Deviation from Reference Ecosystem Index-Ecological Restoration Quality Index (ERQI) to study the evolution of the environment in the study area from the perspective of the whole life cycle of mining activities. The results showed that ERQI values in the study area experienced an evolution process from high to low and then gradually increased, reflecting the impact of coal mine production and restoration activities on the environment, in which Burn Area Index and normalized difference vegetation index were more sensitive; after nearly 10 years of restoration, ERQI values in the study area still had a large gap with that of the reference area, some suggestions for improvement of ecological restoration were put forward. The research provided a quantitative approach to describe the evolution of the ecological environment and a scientific basis for the ecological restoration in the mining areas.
Explainable deep learning approach for recognizing “Egyptian Cobra” bite in real-time
Authors: Elhoseny Mohamed , Hassan Ahmed , Shehata Marwa H. , Kayed Mohammed
Published: February 2025

The Egyptian cobra is among the deadliest snake species, capable of causing death within a short span of 15 min. Also, every snake species has its own anti-venom type. So, a quick identifying the Egyptian Cobra bite from other snake species is a challenging and critical task. This research employs Internet of things (IoT) and deep learning methods to precisely recognize bites of Egyptian cobra, in the real-time, by analyzing images of the bite marks. We deploy IoT-enabled wearable devices equipped with sensors capable of detecting snake bites, whereas these sensors measure changes in physiological parameters indicative of a snakebite, such as heart rate, blood pressure, and temperature sensors based on our proposed mathematical algorithm. Also, we present a real case study in which we used our mathematical algorithm to determine based on its sensor readings whether the victim was exposed to a snake bite or not in the real-time. These wearable devices can be worn by individuals working or living in areas prone to snake encounters, such as farmers. When a snake bite occurs, the IoT sensors embedded in the wearable devices will immediately detect the bite and transmit real-time data, including vital information about the bite marks, to a central monitoring system or victim relative. Also, we assembled a dataset consisting of 500 images depicting Egyptian cobra bites and 600 images of bites from various other snake species indigenous to Egypt. To bolster the model’s trustworthiness and facilitate understanding of its decisions, we employed the contemporary method of explainable deep learning. Also, notably, our methodology yielded an accuracy of 90.9%.
Performance of high strength natural fiber reinforced hybrid composites for structural engineering applications
Authors: Rasu Karthick , Veerabathiran Anbumalar
Published: February 2025

Natural fiber composites are increasingly recognized as a viable alternative to synthetic fiber composites, utilizing materials like flax, hemp, jute, bamboo, and sisal to reinforce polymer matrices. Their eco-friendly nature has garnered attention, presenting a sustainable option in various applications. In structural engineering, these composites find utility in beams, columns, and trusses. This study focuses on investigating the mechanical properties, wear resistance, and water absorption behavior of hybrid composites reinforced with hemp/glass, kenaf/glass, flax/glass, and sisal/glass fibers. The fabrication process involved hand layup techniques to create four distinct composite types using hemp, kenaf, flax, and sisal fibers. To enhance mechanical properties, wear and water resistance, glass fibers were incorporated in the composites. The evaluation of mechanical properties, including hardness, tensile strength, flexural strength, impact strength, compression strength, wear resistance, and water absorption behavior, was conducted according to ASTM standards. The findings reveal that the kenaf/glass fiber reinforced hybrid composite demonstrates favorable mechanical properties, minimal wear rate, and high water resistance. Given its performance, the kenaf/glass fiber composite emerges as a promising candidate for structural engineering applications.
Crystal structure of (E)-(3-(thiophen-2-yl)acryloyl)ferrocene, C17H14FeOS
Authors: Ding Fangfang , Xu Xiaona , Zhu Zhoujing , Tong Hongjuan , Tang Wenqiang
Published: February 2025

C17H14FeOS, monoclinic, P21/n (no. 14), a = 5.8315(3) Å, b = 19.9325(13) Å, c = 11.9563(7) Å, β = 90.11(5)°, V = 1389.75(14) Å3, Z = 4, Rgt
(F) = 0.0386 wRref
(F
2) = 0.0858, T = 170 K.
Crystal structure of (1,4,8,11-tetraazacyclotetradecane-κ
4
N,N′,N″,N‴)palladium(II) tetraiodidopalladate(II), C10H24I4N4Pd2
Authors: Ha Kwang
Published: February 2025

C10H24I4N4Pd2, monoclinic, P21/n (no. 14), a = 8.955(7) Å, b = 15.587(13) Å, c = 14.752(12) Å, β = 95.63(2)°, V = 2049(3) Å3, Z = 4, R

gt
(F) = 0.0564, wR

ref
(F
2) = 0.1562, T = 223 K.
Riemann–Liouville fractional stochastic evolution equations driven by mixed sub-fractional Brownian motion
Authors: Boutlilis Mokhtaria , Kandouci Abdeldjebbar
Published: February 2025

This paper is concerned with the existence of mild solutions for stochastic differential equations driven by mixed sub-fractional Brownian motion with Riemann–Liouville fractional derivative.
The results are obtained by the fixed point theorem.
An example is given to illustrate the obtained results.
Nuteistųjų resocializacija kalėjimų pusiaukelės namuose: nuteistųjų patirtisresocializacija kalėjimų pusiaukelės namuose: nuteistųjų patirtis
Authors: Gerybaitė Gintarė
Published: February 2025

Since 2016, part of the process of resocialization of inmates has been implemented by the half-way house institute. The article reveals the results of an exploratory study on the resocialization of convicts who continue their prison sentences in half-way houses. The issues raised in this article are related to the implementation of resocialization measures in the half-way houses, factors influencing the resocialization in the half-way houses, and the prospects for the development of quality-based resocialization in the half-way houses.
The research has revealed the possible significance of the resocialization in the half-way houses for the inmate, the importance of staff assistance, and the peculiarities of resocialization activities in the half-way house. An inmate getting transferred to a half-way house is associated with proof of the progress made along with an opportunity to start a new life. The factors revealed by the study which possibly facilitate the preparation for the return to society from the half-way house are associated with half-way house staff and open prison conditions. The research has identified the possible perspectives and developments of the practices applied in the half-way house. The list of possible developments includes the improvement of the physical conditions in the half-way house. Also, the improvement of the rules of the internal order and the introduction of new measures for the inmates in the half-way house have been distinguished as promising directions for further developments.
Aula invertida para el aprendizaje de ecuaciones de primer grado en el estudiantado de undécimo año
Authors: Díaz Porras Jorge Alonso
Published: February 2025

Este artículo tiene el propósito de exponer la problemática, el sustento, la metodología y los hallazgos de un estudio cuyo objetivo fue describir las mejoras propiciadas por la estrategia del aula invertida en el aprendizaje de ecuaciones de primer grado en estudiantes de undécimo año, en San José, Costa Rica. En la fundamentación teórica referencial del estudio se exponen planteamientos del aprendizaje significativo, social y autodirigido, así como principios del constructivismo de Piaget. Se empleó el método cuantitativo con un diseño preexperimental y descriptivo. Se aplicó un pretest, una intervención y un postest en una población de 195 estudiantes. La intervención consistió en la aplicación del aula invertida, utilizando recursos digitales para la revisión autónoma antes de las clases presenciales. Se evaluaron aspectos teóricos y prácticos de las ecuaciones de primer grado, revelando mejoras significativas en la comprensión y aplicación de las ecuaciones, y una reducción en el porcentaje de estudiantes con puntajes bajos. A pesar de los desafíos observados en la resolución de ecuaciones y problemas, el estudio concluyó que la estrategia del aula invertida propició cambios positivos en el aprendizaje de ecuaciones de primer grado. Estos resultados avalan su eficacia pedagógica y sugieren su implementación en la enseñanza de matemáticas y ciencias exactas, donde su enfoque podría potenciar significativamente el aprendizaje.
Diferencias Técnicas en la Enseñanza del Canto Popular vs. Canto Lírico
Authors: López Pacheco María Marta , Viales Montero Rebeca Patricia
Published: February 2025

Para el profesorado de canto resulta fundamental comprender los usos voluntarios e involuntarios de las estructuras anatómicas de la voz y del tracto vocal, así como las particularidades de los géneros musicales y las características vocales individuales de los y las estudiantes. El objetivo de este ensayo es exponer las diferencias y semejanzas entre el canto lírico y el canto popular y su aplicación según el género a interpretar. Para ofrecer un análisis profundo, se realizó una investigación bibliográfica, complementada con aportes y observaciones de las autoras. Los resultados muestran un aumento en el volumen de estudios, especialmente en Norte y Suramérica, sobre el canto popular en las últimas dos décadas, destacando diferencias notables en aspectos como: la posición laríngea, la forma del tracto vocal, la mecánica de la presión subglótica, la intensidad, las características acústicas, el uso de dispositivos electrónicos y la flexibilidad para modificar la música y los colores de la voz. Se concluye que, las diferencias entre el canto clásico y popular condicionan cómo se debe enseñar el canto, por lo que las personas docentes deben concienciar sobre tres puntos: primero, cantar bien no implica enseñar bien, sino que hay que formarse en la educación vocal. Segundo, para enseñar géneros diferentes al que se aprendió y se ejecuta, también es necesaria una formación específica. Por último, ningún género es mejor o más valioso que el otro, cada uno tiene demandas vocales y formas de interpretar, sentir y comunicar diferentes.
Interacciones didácticas en el aula bilingüe sorda para el aprendizaje de la lengua de señas chilena
Authors: Acuña Robertson Ximena , Lattapiat Navarro Pamela
Published: February 2025

Estudio realizado en una escuela especial de personas sordas, con enfoque bilingüe, se centra en los primeros niveles de educación. El objetivo del trabajo consistió determinar cuáles y de qué manera las interacciones comunicativas en lengua de señas chilena (LSCh), que ocurren en el trabajo didáctico, entre docentes y escolares, son significativas para el desarrollo de la LSCh. Estudio de caso de tipo cualitativo de carácter exploratorio y descriptivo. Participaron tres grupos de estudiantes, entre los 5 y 10 años. Estos fueron grabados durante las clases de Lenguaje. El análisis se centró en las prácticas comunicativas del personal docente oyente y se identificaron herramientas didácticas para el desarrollo lingüístico. Los hallazgos permitieron destacar que predominan las interacciones donde el equipo docente inicia y domina los intercambios comunicativos, que se focalizan principalmente en la forma de las señas más que en su contenido y prevalece el énfasis sobre unidades léxicas aisladas.  La manera como el profesorado emplea la LSCh y particularmente, los recursos gestuales y visuales, así como también, los intercambios comunicativos que propician al interior del aula son cruciales, para el aprendizaje de la LSCh, por parte del estudiantado. La relevancia de este estudio se centra en la posibilidad que brinda al equipo docente de monitorear sus propias interacciones y comprender su rol crítico como favorecedores del desarrollo del lenguaje.
Penile metastasis of prostate cancer imitating Peyronie's disease detected on [68Ga]Ga-PSMA-11 PET/CT
Authors: Rogic Ivan , Rubic Mateja , Huic Drazen
Published: February 2025

[68Ga]Ga-PSMA-11 PET/CT (Gallium prostate-specific membrane antigen positron emission tomography/computed tomography) is an established molecular imaging technique for identifying the spread of prostate cancer in patients with biochemical recurrence (BCR) and for initial staging. Penile metastases from prostate cancer are very rare and can be easily misdiagnosed as noncancerous nodules as part of Peyronie's disease. Most cases of penile metastases occur in patients with disseminated disease and are typically diagnosed at advanced stages. In this case, a 74-year-old patient with prostate cancer underwent a successful prostatectomy, ADT, and radiation therapy to the prostate bed, achieving a PSAnadir of 0.01 ng mL−1. Three and a half years after surgery, biochemical recurrence occurred, and the patient was referred to our clinic for a [68Ga]Ga-PSMA-11 PET/CT scan. PET/CT revealed pathological PSMA expression in a proximal part of the penile root, later confirmed by pathohistological analysis as prostate cancer metastasis. Notably, our patient had a PSA value of only 0.53 ng mL−1, one of the lowest serum PSA values reported in the literature for penile metastasis. This case underscores the critical role of [68Ga]Ga-PSMA-11 PET/CT in differentiating benign conditions like Peyronie's disease from metastatic lesions and in detecting rare and unusual metastatic sites.
Clinical and laboratory peculiarities of pregnancy course complicated with gestational diabetes mellitus and exocrine pancreatic insufficiency
Authors:   Bogomolets National Medical University, Kyiv, Ukraine, Kupchik L.M. , Kupchik V.I. ,   Bogomolets National Medical University, Kyiv, Ukraine
Published: February 2025

The course of pregnancy can be accompanied by a number of adverse conditions, one of which is gestational diabetes mellitus (GDM). Reduced glucose tolerance is an adaptive mechanism during pregnancy, but the development of GDM is based on a certain decompensation of pancreatic functions, which may affect not only endocrine but also exocrine pancreatic activity (EPA).
Aim - to study the anamnestic, clinical and laboratory features of the course of pregnancy with reduced EPA in GDM.
Materials and methods. The study involved 112 patients (87 women from the main group, divided into 2 subgroups according to the presence of dyspeptic symptoms; and 25 pregnant women from the control group). Anamnestic data, the course of this pregnancy were studied and enzyme immunoassays for serum trypsinogen (TPG) and fecal elastase-1 (FE-1) concentrations were performed. Statistical analysis conducted using Microsoft Office Excel and MedStat software. The difference between groups was considered significant at p≤0.05.
Results. In pregnant women with GDM and reduced EPA, the presence of factors in the anamnesis that potentially affect the development of pancreatic diseases was established. Significantly lower TPG and FE-1 levels were found in the main group compared to the control group. A direct relationship was determined between the degree of reduction in EPA in GDM and clinical manifestations of dyspepsia, as well as with the occurrence of early pregnancy complications.
Conclusions. Increasing maternal age, previous gastrointestinal diseases, polycystic ovary syndrome, and obesity are associated with a greater severity of decreased EPA in women with GDM, clinically manifested by the occurrence of dyspeptic manifestations, vomiting of pregnancy, and threatened abortion; laboratory findings were: decreased TPG and FE-1 concentrations, which correlate with the severity of clinical picture.
The study was conducted in accordance with principles of the Declaration of Helsinki. Research protocol was approved by local ethics committee of the participating institution. Informed consent was obtained.
The authors declare no conflict of interest.
Comprehensive assessment of the hemostatic system in women with РAI-1 gene polymorphism and first trimester pregnancy loss
Authors:   Dnipro State Medical University, Ukraine, Panov V.V. , Duka Yu.M. ,   Dnipro State Medical University, Ukraine
Published: February 2025

Aim - to study the associations between hemostatic system parameters, natural anticoagulant levels and serum PAI-1 levels depending on the PAI-1 polymorphism variant in women with early reproductive losses.
Materials and methods. The selected patients (n=115) were divided into 3 groups according to the type of polymorphism: Clinical group I (n=20) - patients with wild-type polymorphism of the РAI-1 gene (675 5G>5G), group II (n=53) - women with heterozygous polymorphism of the РAI-1 gene (675 5G>4G), group III (n=42) - women with homozygous pathological polymorphism of РAI-1 (675 4G>4G). The study was based on bibliosemantic analysis; anamnestic data were evaluated; polymerase chain reaction (PCR) was used to determine thrombophilia gene polymorphisms; enzyme-linked immunosorbent assay (ELISA) to determine the level of РAI-1 in the blood serum; clotting method to determine the levels of natural anticoagulants; coagulometric method to determine the level of fibrinogen and coagulation parameters.
Results. The average age of women in the thematic groups was comparable and amounted to 32.5±0.9, 33.9±0.7 and 33.6±0.7 years, respectively. The analysis of associations in the comprehensive assessment of haemostatic parameters revealed certain associations between these parameters and a complicated obstetric history (spontaneous abortion, fetal growth retardation and pre-eclampsia, pregnancy loss in early (more frequent) and late gestation), and the presence of РAI-1 gene polymorphism. No significant associations were found between the presence of the РAI-1 gene polymorphism and levels of natural anticoagulant activity. The level of РAI-1 depended on the type of polymorphism in this gene and was associated with termination of pregnancy before 12 weeks.
Conclusions. Polymorphisms of the PAI-1 gene should be considered as one of the risk factors for habitual miscarriage. Overexpression of PAI-1 is associated with adverse pregnancy complications, and its level is an extremely promising marker for prognosis and treatment effectiveness.
The research was carried out in accordance with the principles of the Helsinki Declaration. The study protocol was approved by the Local Ethics Committee of the participating institution. The informed consent of the patient was obtained for conducting the studies.
No conflict of interests was declared by the authors.
Management of patients with abnormal screening results and precancerous conditions of the cervix according to national standards 2024 (clinical case)
Authors:   Dnipro State Medical University, Ukraine, Lebedyuk V.V.
Published: February 2025

Аim - to solve the problem of early diagnosis and treatment of pathological conditions of the cervix in accordance with the national standard of medical care (order of the Ministry of Health of Ukraine No. 1057) using the example of a clinical case analysis.
Clinical case. Patient B., born in 1986, complained of periodic pain in the lower abdomen and the inability to get pregnant for 7 years. Additional examination was performed: the conclusion of liquid cytology ASC-US, HPV genotyping revealed 16, 18, 31 HPV genotypes. Full diagnosis as: Primary infertility. ASC-US (atypical squamous epithelial cells of unclear genesis). Immediate risk of CIN 3+ 4.4%. Clinical form of HPV (16, 18, 33 genotypes). Ectopia of the cervix. Transformation zone type 1. Chronic cervicitis. Anti-inflammatory therapy was performed. Diagnosis after treatment: HSIL, AGUS. Immediate risk of CIN 3+ 32%. Clinical form of HPV (16). Ectopia of the cervix. Transformation zone type 1. Chronic cervicitis. Was targeted radio wave excision of the cervix was performed. The results of the pathohistological examination indicated low-grade squamous intraepithelial lesion LSIL, atypical glandular cells were not detected. Diagnosis: LSIL. Immediate risk of CIN 3+ 2.9%. Clinical form of HPV (16). Ectopia of the cervix. Transformation zone type 1. Taking into account the recommendations of the standard, after receiving the appropriate histological conclusion, we can subsequently observe the woman for 1 year.
Conclusions. The analysis of a clinical case indicates that for the timely diagnosis of intraepithelial lesions of the cervix, it is necessary to conduct cervical screening, sorting additional examination and determining the risk of CIN 3+. If cervical screening is already standardized in gynecological practice, sorting additional examination and determining the risk of CIN 3+ are new concepts that are generally not used.
The study was performed in accordance with the principles of the Declaration of Helsinki. The woman's informed consent was obtained for the study.
The author declares that there is no conflict of interest.
Identification of Inpari HDB 32 Superior Rice Seeds based on Android in Realtime with Artificial Neural Network
Authors: Akram Rizalul , Atmaja Teuku Hadi Wibowo , Novianda
Published: February 2025

Rice is a staple food for humans living in East Asia. Rice is a crystal fruit. The Latin name for rice is Oryza Sativa. Rice plants are 110-120 days old. The selection of quality rice seeds by farmers is seen from the bright yellow color of the rice without black/brown spots, its large size and rounder. Rice seeds that are not of good quality are dark brown in color, have black/brown spots, and are flat in shape. The absence of superior rice recognition technology that is not Android-based in real time is the main reason for this research. The focus of this research is to identify superior and non-superior rice in Inpari HDB 32 rice with a high recognition accuracy rate of more than 70 percent with a viewing angle of 0-180 degrees using the real-time ANN method. The training data used in this research was 1000 datasets consisting of 350 superior rice datasets and 650 non-superior datasets. The smart model for classifying rice seeds that has been built in this research is generally able to run well where the classification accuracy obtained is quite good. The classification accuracy of the ANN model during training of the neural network model was able to classify rice seeds with an accuracy of 70-100% with the confidence value of the real-time classification results ranging from 65-98%. Real-time classification of rice grains with maximum accuracy of 96% and many grains 73%.
Changes in the prevalence of severe anxiety and depression symptoms and the associated factors in adults living in Manaus: a comparison of two cross-sectional studies conducted in 2015 and 2019
Authors: Lima Vanessa Gomes , Silva Marcus Tolentino , Tiguman Gustavo Magno Baldin , Galvão Taís Freire
Published: February 2025

ABSTRACT BACKGROUND: Emotional distress increases, also affected by the setting. OBJECTIVE: To estimate changes in prevalence of severe anxiety and depressive symptoms and associated factors. DESIGN AND SETTING: This cross-sectional study included adults living in Manaus selected through a three-stage probability sampling in 2015 and 2019. METHODS: This is an analysis of two surveys conducted. The outcomes were assessed by Generalized Anxiety Disorder 7-item (≥ 15 points) and Patient Health Questionnaire 9-item (≥ 20), and changes were tested by chi-square goodness-of-fit. Prevalence ratios (PR) with 95% confidence intervals (95%CI) were calculated by Poisson regression. RESULTS: Severe anxiety symptoms increased from 3.3% (95%CI = 2.7–3.9) in 2015 (n = 3,479) to 8.7% (95%CI = 7.5–9.8) in 2019 (n = 2,321); severe depressive symptoms changed from 2.5% (95%CI = 2.0–3.0) to 8.5% (95%CI = 7.3–9.6). Variations were more pronounced in social vulnerability (P < 0.05). Outcomes were higher in women (anxiety: PR = 1.27; 95%CI = 1.20–1.34, depression: PR = 1.35; 95%CI = 1.27–1.44), low-income individuals (anxiety: PR = 1.90; 95%CI = 1.20–3.00, depression: PR = 1.98; 95%CI = 1.22–3.19), less educated individuals (anxiety: PR = 2.20; 95%CI = 1.16–4.18, depression: PR = 2.37; 95%CI = 1.23–4.60), and individuals with poor health status (anxiety: PR = 9.06; 95%CI = 6.72–12.21, depression: PR = 8.99; 95%CI = 6.67–12.12). CONCLUSION: Severe anxiety and depression tripled in Manaus, potentially reflecting Brazilian socioeconomic crises.
Medindo a circularidade dos resíduos: caminhando para uma economia circular
Authors: Mesquita Míriam Machado Fabris , Sabbadini Francisco Santos , Costa Kelly Alonso
Published: February 2025

Resumo O modelo de produção linear, que extrai matéria-prima e descarta produtos, está chegando ao seu limite. Por esse motivo é necessário encontrar soluções para evitar o desperdício. A economia circular defende a ideia de que os materiais continuem em uso pelo maior tempo possível e tem como um dos princípios a eliminação de resíduos. O presente trabalho teve como objetivo medir a circularidade dos resíduos de uma indústria de produção de vidros planos, através de um indicador, que comparou cenários dentro de uma empresa. Para isso foram feitas comparações entre o cenário real da empresa com o pior e melhor cenários da mesma. O indicador mediu a circularidade dos resíduos da empresa e demonstrou ser uma ferramenta útil para implementar melhorias em função do reaproveitamento de resíduos. O cálculo do indicador indicou que a empresa representou 83% do cenário ideal, onde todos os resíduos são reaproveitados.
A comprehensive review on frontotemporal dementia: its impact on language, speech and behavior
Authors: Mollah Sha Abbas , Nayak Aditya , Barhai Swapna , Maity Uddip
Published: February 2025

ABSTRACT. Frontotemporal dementia (FTD) is a progressive neurodegenerative disorder defined by the selective deterioration of the frontal and temporal lobes of the brain. This comprehensive review explored the effect of FTD on language, speech, and behavior. Early symptoms include difficulty in word finding, reduced speech output, and comprehension deficits, often leading to aphasia. The study discussed the profound behavioral changes observed in FTD patients, including apathy, disinhibition, compulsive behaviors, and loss of empathy, the importance of an accurate and early diagnosis, and its challenges. We even reviewed the potential for targeted therapies and the essential role of multidisciplinary care in managing the language, speech, and behavioral aspects of FTD. By examining objective data and comprehensive research on the subject, this study offers valuable insights into FTD’s profound effects on language, speech, and behavior, assisting in improved clinical management and potential therapeutic strategies for this devastating condition.
Monitoring risk factors for dementia in middle-aged and older adults: a longitudinal study
Authors: Luchesi Bruna Moretti , Kajiyama Mariana Tiemi , Abreu Amanda Rocha , Kwiatkoski Marcelo , Martins Tatiana Carvalho Reis
Published: February 2025

ABSTRACT. Given the importance of dementia syndrome and its impacts on the population, interest in studying modifiable risk factors for dementia is growing. Objective: To compare the prevalence of risk factors for dementia in middle-aged and older adults over a two-year period and to identify what variables in baseline were predictive of cognitive decline in the follow-up. Methods: Longitudinal and quantitative study, with follow-up evaluation after two years, conducted with 200 participants aged 45 years or more, registered in Primary Care Units. In the baseline (2018/2019) and follow-up (2021) assessments, sociodemographic data were collected, and cognitive performance and risk factors for dementia were evaluated (education, hearing loss, head trauma, high blood pressure, alcohol use, obesity, smoking, depressive symptoms, social isolation, physical inactivity, and diabetes mellitus). Data were compared using the McNemar’s test. Individual multinomial logistic regression models were performed to identify the factors associated with cognitive decline after two years. Results: The percentages of low education, traumatic brain injury, and smoking remained the same in both assessments. There was a significant increase in the prevalence of high blood pressure (from 55.0 to 62.0%) and physical inactivity (from 58.5 to 74.5%) and a significant reduction in social isolation (from 25.0 to 18.0%). Participants with depressive symptoms in baseline had a higher risk of cognitive decline in follow-up. Conclusion: There was an increase in the prevalence of high blood pressure and physical inactivity and a reduction in social isolation after two years. Depressive symptoms predict cognitive decline.
Dificuldades no aleitamento materno pós mamoplastia de aumento: revisão de escopo
Authors: Pereira Raquel Ruzicki , Rech Rafaela Soares , Schiavoni Laura Battistin , Berbert Monalise Costa Batista
Published: February 2025

RESUMO Objetivo: identificar e descrever dificuldades observadas no aleitamento materno em mulheres submetidas à cirurgia de mamoplastia de aumento. Métodos: trata-se de uma revisão de escopo, com a pergunta norteadora: “Quais as possíveis dificuldades na amamentação observadas em mulheres que realizaram a mamoplastia de aumento descritas na literatura?”. A estratégia de busca foi realizada com combinações de descritores para a busca nas bases Lilacs, SciELO, Cochrane CENTRAL, BIREME, Pubmed, ADOLEC, BDENF, MedCarib e literatura cinzenta, sendo 12 de outubro de 2023 a data da última busca. Foram incluídos artigos completos, sem restrição de idioma e tempo de publicação, delineamento observacional, e que analisaram mulheres com histórico de mamoplastia de aumento e possíveis dificuldades na amamentação. Revisão da Literatura: foram incluídos sete artigos. Os estudos identificaram como possíveis dificuldades no aleitamento materno em mulheres submetidas à cirurgia de mamoplastia de aumento: a presença de ingurgitamento mamário, mastite, dor, lesões mamilares e alterações de lactação e de sensibilidade envolvidas no aleitamento materno. Conclusão: espera-se que os resultados apresentados nesta revisão de escopo estimulem o desenvolvimento de evidências mais vigorosas sobre a relação entre estes achados.
O Conceito de Reendereçamento na Pesquisa sobre Educação e Cinema
Authors: Rezende Filho Luiz Augusto Coimbra de , Santos Gisele Abreu Lira Corrêa dos , Bastos Wagner Gonçalves , Pastor Junior Américo de Araujo
Published: February 2025

RESUMO Este artigo apresenta bases teóricas e desdobramentos analíticos do conceito de reendereçamento para a pesquisa na área de Educação e Cinema. Este conceito se refere às mediações produzidas sobre uma obra audiovisual para adaptá-la ao ensino, e permite descrever e analisar modos de atuação docente em aulas com exibição audiovisual de forma a identificar aspectos preponderantes e intervenientes nas condições de ensino e aprendizagem. Apresentamos ainda as estratégias de reendereçamento audiovisual, os modos de leitura e deslocamentos espectatoriais mais frequentemente encontrados no ensino, e os saberes mobilizados pelos professores para reendereçar. Por fim, indicamos contribuições e perspectivas do conceito para a pesquisa.