bluuebunny/crossref_metadata_2025 huggingface dataset:
P-478 ASSESSMENT OF THE IMPACT OF LOW-DOSE IONIZING RADIATION EXPOSURE ON THYROID GLANDS, AMONG MEDICAL RADIATION WORKERS
Authors: Hrar Wiame
Published: July 2024

Introduction

While prior research evinces that acute IR exposure contributes to cancer growth, this research aims to assess the risk of thyroid cancer in thyroid nodules and parenchymal heterogeneity among medical radiation workers (MRW) due to low-dose chronic radiation exposure, primarily driven by the growing utilization of radiation in diagnostic medical procedures.

Methods

This study conducted by M.F.Baran and A.E.Atas, includes 148 MRW from Konya City Hospital, aged between 18 and 65 with no prevalence. They were divided into groups according to their sociodemographic and professional information. Their TSH levels, and thyroid ultrasonography (US) data were also collected. The detected thyroid nodules were classified based on the ACR TI-RADS method.

Results

The analysis revealed that the prevalence of thyroid nodules increases with age and years of employment, especially in workers over 33 (p=0.02) and participants with chronic diseases (p=0.003).The experiments demonstrate a significant correlation between thyroid parenchymal heterogeneity and increased TSH levels, implying that nodules tend to develop in the presence of hypothyroidism or thyroiditis. The differences in work department or gender didn’t impact these factors. The majority of nodules found were benign.

Discussion

This retrospective study attests that MRW are at higher risk of developing thyroid nodules than the overall population when facing a longer radiation exposure. However, it discards the idea of a higher risk of thyroid cancer. Further research is needed to explore alternative risk factors for thyroid cancer within this occupational group.

Conclusion

Regular screening and radiation protection measures are important to promote better health management.
P-479 EVALUATION OF THE DEPOSED DOSES IN A RADIOTHERAPY TREATMENT ROOM USING THE MONTE CARLO GEANT4 SIMULATION PLATFORM
Authors: Meftah Asmae , Krim Mustapha , Ghazi Ismail , Talib Zineb
Published: July 2024

Introduction

Radiotherapy is considered one of the primary treatment choices in cancer management. The aim of our study is calculating the dose deposited in different points of a radiotherapy treatment room using a phantom detector to quantify the secondary particles around the latter to evaluate the radioprotection level for both the patient and the radiotherapy technician as we increase the distance longitudinally and laterally between the patient and the detector.

Methods

We used GEANT4 code based on Monte Carlo methods to simulate the radiotherapy treatment room components including the water tank that we centered underneath the beam with a 4.5 MV which is the average energy of the X18 energy spectrum and a fluence of 107 cm−2 to calculate the deposited doses.

Results

We moved the phantom detector with a step of ±70 cm longitudinally and laterally along X and Z respectively. Findings show that the deposited doses decrease when moving the detector away from the beam’s center for both directions, but it seems higher in the center for X = Z = 0 cm.

Discussion

The results indicate that even though we increase the distance either longitudinally or laterally between the beam and the detector the diffused dose persists regardless it represents a small amount the fact that validates the principle of distance for protection against external exposure.

Conclusion

Radiotherapy proved to be highly effective to kill cancer cells, yet the diffused dose persists still inside radiotherapy treatment rooms which creates a debate regarding radioprotection for the patient and the radiotherapy technician.
P-480 HEMATOLOGIC MONITORING OF WORKERS EXPOSED TO IONIZING RADIATION STUDY AT THE RADIOLOGY DEPARTMENT OF HOSPITAL LA RABTA
Authors: Fatma Naourez Ben , Ismail Saloua , Baraketi Emna , Khouja Nihel , Hsinet Jihen , Benzarti Aida
Published: July 2024

Introduction

Prolonged exposure of radiology healthcare workers (HCW) to ionizing radiation (IR) could have harmful effects on the bone marrow.

Objectives

To describe the socio-professional and clinical characteristics of HCW exposed to IR and to detect any abnormalities in the complete blood count(CBC).

Methods

Cross-sectional descriptive study carried out in January 2023, with the HCW exposed to IR from the radiology department. The data collection was done through a pre-established questionnaire completed by a blood sample for the realization of the CBC.

Results

We included 40 HCW of which 28 women. The mean age was 38.5. The most represented workstation was that of medical imaging technician. They worked behind a lead screen in 73% of cases and they did not wear a dosimeter in 35% of cases. Clinically, they reported asthenia (60%), and gingival bleeding (28%). CBC analysis revealed an average number of red blood cells of 4.7 ± 0.5* 106 with a low level in 3% of cases, an average hemoglobin level of 13.4 ± 1.7 g/ dl, microcytosis (25%), macrocytosis (3%) and hypochromia (18%). Anemia was thus objectified in eight women. The mean number of white blood cells was 7379.8 ± 1706.1/mm3 lymphopenia (5%) and no cases of neutropenia. The average number of platelets was 277375 ± 64720.2/mm3 with thrombocytosis in 5% of cases.

Discussion

The CBC is a simple and accessible screening test carried out as part of the special medical surveillance of HCW exposed to IR in addition to dosimetric monitoring.

Conclusion

Technical prevention, both collective and individual, will always deserve to be strengthened.
O-324 THE ESTABLISHMENT OF A DANISH, NATIONWIDE PARENT-CHILD COHORT WITH OCCUPATIONAL EXPOSURE DATA (DOC*X-GENERATION)
Authors: Begtrup Luise Moelenberg , Bonde Jens Peter , Flachs Esben Meulengracht , toettenborg Sandra Soegaard , Pedersen Marie , Hougaard Karin Soerig , Sejbaek Camilla Sandal
Published: July 2024

Introduction

Many birth cohorts were established worldwide after the introduction of the developmental origins of health and disease hypothesis in the late 1980s; but studies on rare exposures and outcomes are still underpowered. To address this limitation, we established a nationwide cohort including all pregnant women affiliated to the labor market before and during their pregnancy in Denmark during 1977-2018 and with linkage to the fathers and their born children.

Methods

The DOC*X-Generation cohort includes all Danish women with ≥1 registered pregnancy during employment, established with individual level records from: population registers (Statistics Denmark), the Medical Birth Registry and the National Patient Registry, the Occupational and Industry Register including job codes, DISCO-88 (Danish version: International Standard Classification of Occupations) and industry codes. By DISCO-88 codes, sex, age, and time periods, the individual level data are combined with several Job Exposure Matrices (JEMs), e.g., psychosocial, noise or chemical exposures, and four JEMs on health behaviors (smoking; alcohol; leisure-time physical activity; vegetable intake).

Results

Data consists of approx.3.5 million pregnancies (approx.1.5 million women) of which approx.2.5 million resulted in liveborn children.

Discussion

Studies of maternal psychosocial and physical strain at work during pregnancy and risk of adverse pregnancy outcomes as well as on maternal absence are ongoing.

Conclusion

A cohort with this level of details, size and structure provides great opportunities to investigate occupational exposure over time, rare exposures, and rare outcomes. The cohort offers unique opportunities for studies of maternal and transgenerational impact of occupational exposure on pregnancy outcomes and health.
O-326 TEMPORAL TRANSITION TRENDS OF CORD BLOOD LEAD LEVELS IN VARIOUS HUMAN DEVELOPMENT INDEX COUNTRIES AND IN THE TAIPEI METROPOLITAN AREA
Authors: Hwang Yaw-Huei , Wu Hui-Chu , Shyu Ming-Kwang , Lee Chien-Nan , Lin Shin-Yu , Chen Pau-Chung , Chuang Hung-Yi , Lin Pei-Wen , Wu Tso-Hsien
Published: July 2024

Introduction

Since low-level lead exposure is still of concern for neonates, it is worth further characterizing the temporal transition trends of cord blood lead levels (CBLLs) globally and locally in Taipei, Taiwan, after the cessation of leaded gasoline use.

Methods

A literature review on CBLLs around the world was performed by searching three databanks, i.e., PubMed, Google Scholar and Web of Science, with the search keywords “cord blood” combined with “lead” or “Pb” for studies published from 1975 to May 2021.

Results

In total, 67 articles were included. Linear regressions for the reciprocal of sample size weighted CBLLs against calendar year presented a high r2 value (0.732) for the very high Human Development Index (HDI) countries and a moderate r2 value (0.287) for the combined high and medium HDI countries. The predicted CBLLs in 2030 and 2040 were 6.74±0.42 µg/L and 5.70±0.38 µg/L, respectively, for the very high HDI countries and 14.60±3.50 µg/L and 11.89±3.11 µg/L, respectively, for the combined high and medium HDI countries. To characterize the CBLL transitions in the Great Taipei metropolitan area, data from five studies conducted from 1985 to 2018 were employed. The CBLLs of the latest study during 2016-2018 were 8.1 ± 4.5 μg/L, approximately 3 years in advance of the very high HDI countries as one group to reach this low CBLL.

Discussion and conclusion

Further effective reduction in environmental lead exposure is challenging and must be based on the efforts from the aspects reflected by the HDI index compositions, i.e., economics, education and health.
O-329 EVALUATION OF 1.3 MILLION POST EXPOSURE EXAMINATIONS IN ASBESTOS WORKERS FROM GERMANY – TIME TRENDS IN DETECTION RATES OF ASBESTOS-RELATED DISEASES
Authors: Kraus Thomas , Esser Andre , Centmayer Alexandra , Wolff Christian , Raithel Hans-Jürgen
Published: July 2024

Introduction

In Germany it is mandatory for employers to offer periodical examinations even after the end of asbestos exposure. To support this, the employers` accident insurances established a central registry for formerly exposed asbestos workers in 1972. In this study we aimed at describing time trends in the detection rates of asbestos related diseases (ARDs) over almost 50 years.

Study group and methods

From 1972 to 2020 1.374.579 examinations from 321.701 persons with information on exposure history, smoking habits, diseases, physical examination and chest X-ray with ILO-classification were stored at the central registry. In the first step, we evaluated detection rates of ARDs per year and compared the results with the annual statistics of occupational diseases (ODs) in Germany. Numbers needed to screen to detect one case (NNS) were calculated.

Results

Average numbers needed to screen to detect one case were 63 for non-malignant ARDs, 1105 for lung cancer and 4111 for mesothelioma. Time trends show that NNSs are steadily increasing over time. Compared with OD statistics 36.8% of non-malignant ARDs but only 5% of lung cancer and 1.6% of mesothelioma cases were reported from post exposure examinations.

Conclusions

Post exposure examinations detected significant numbers of ARDs during the last 50 years. However, NNSs are increasing due to dust prevention, better personal protection and asbestos ban in 1993. Moreover, due to the long latency periods relevant numbers of ARDs are still to be expected. Measures to improve efficiency (targeted prevention) should be discussed.
O-330 PREVALENCE OF RESPIRATORY SYMPTOMS, DISEASES AND VENTILATORY DISORDERSAMONG MARBLE WORKERS
Authors: Rkiek Bilal , Manar Nadia , Bouri Hicham El , Deschamps Frédéric , Laraqui Chakib
Published: July 2024

Introduction

The aim of this study was to assess the prevalence of respiratory symptoms, diseases and ventilatory defects.

Methods

This cross-sectional study involved 365 marble workers in Casablanca, and Agadir, with at least two years’ seniority. It included a questionnaire, spirometry and thoracic radiophotography. The questionnaire consisted of four sections: socio-demographic and occupational characteristics, smoking habits, medical history and clinical respiratory symptoms. Chronic bronchitis is defined as chronic cough and chronic sputum production occurring for at least three months per year and for at least two consecutive years without any other identified cause. The diagnosis of COPD was made in the presence of an obstructive ventilatory defect based on a ratio of forced expiratory volume at the first second/ forced vital capacity (FEV1/ FVC) <70% after administration of a bronchodilator.

Results

Average age was 38,5±10.4 years. The average seniority was 13,1 ±6.4 years. 23,3% were current smokers, 12.3% former smokers and 64.3% non-smokers. The prevalence of tracheobronchial irritation symptoms was 23.5: 15 % for chronic cough, 7.8 % for respiratory discomfort, 4.9 % for chronic sputum and 7.9% for chest wheezing. The prevalence of rhinitis was 20%, asthma 7.5%, chronic bronchitis 17% and chronic obstructive pulmonary disease 6.2% (6.9% in current and former smokers versus 2.9% in non-smokers). 21.3% had deficits in the (FEV1) and the (FVC). This prevalence reached 44% in current and former smokers. The prevalence of radiological abnormalities was 14.9% (3.8% were emphysema, 3.3% were small parenchymal opacities suggestive of pneumoconiosis).

Conclusion

These craftsmen must benefit from occupational medical coverage for better prevention.
P-484 POST-COVID-19 SYNDROME IN HEALTHCARE WORKERS – EMPHASIS ON RESPIRATORY SYSTEM
Authors: Shpagina Lyubov , Bukhtiyarov Igor , Kuzmina Liudmila , Shigan Evgeny , Kondyurina Elena , Shpagin Ilya , Kotova Olga , Kuznetsova Galina , Kamneva Natalya , Anikina Ekaterina , Likhenko-Logvinenko Kristina
Published: July 2024

Introduction

Healthcare workers (HCW) were at the frontline of COVID-19 pandemic. Currently the burning issue for this occupational group is chronic post-COVID-19 syndrome that leads to work disability. The study aim was to reveal severity and predictors of pulmonary fibrosis (PF) in HCW with post-COVID-19 syndrome.

Methods

An observational prospective study over a 3-years period was conducted. HCW with COVID-19, confirmed by polymerase chain reaction (PCR) were included (n=152). After 4 months, 56 post-COVID-19 syndrome patients continued the study. Using propensity matched score, they was matched 1:1 by age and gender with post-COVID-19 patients, non-HCW, without occupational risk (control group, n=56). High resolution computer tomography (HRCT) (semi-quantitative method) was used to assess PF. Pulmonary function tests, SARS-CoV-2 viral load by PCR, serum proteins measurement by ELISA was done. Logistic regression was used to explore relationships.

Results

Frequency of PF did not differ between groups, but the proportion of cases with percent fibrosis of 50%-100% was higher in HCW (OR 3.4, 95% CI 1.50-7.80). Pediatricians had maximum risk of severe PF (OR 4.79, 95% CI 1.17-15.85). In multivariate analysis, CT score (OR 1.05, 95% CI 1.01-0.09), respiratory support duration (OR 1.37, 95% CI 1.12-1.68), maximum cycle threshold (Ct) (OR 0.72, 95%CI 0.60-0.87) and serum transforming growth factor-β1 (TGF- β1) (OR 1.05, 95%CI 1.02-1.08) during the acute COVID-19 were associated with severe PF after 3 years in HCW.

Discussion

HCW, especially pediatricians, had high risk of persistent severe PF. Potential predictors of severe PF at a long term period were established.

Conclusion

Post-COVID-19 syndrome in HCW is characterized by severe PF.
P-485 MEDICAL EXPERTISE ASSESSMENT IN OCCUPATIONAL ASTHMA: CASES STUDY
Authors: Abouzahir Hind , Elhamamouchi Ikram , Belhouss Ahmed , Benyaich Hicham
Published: July 2024

Background

Occupational asthma is one of the most commonly reported occupational respiratory diseases in industrialized countries. Identification of common causative agents and clinical symptoms through medical expertise is necessary to be eligible for compensation.

Methods

All cases of occupational asthma diagnosed from 1st January 2012 to 31st December 2022 through medical expertise were included in the study of Casablanca Medico Legal Institute.

Results

A total of six cases of confirmed occupational asthma were identified. Of these, one was sensitizer-induced and five were irritant-induced asthma. Low molecular-weight agents like isocyanates, phthalates, pulverized vegetable gums, inhalation of acid anhydrides and wooden dusts were being the most common causal agents in our cases. The majority of cases emanated from the Engineering, Chemical, agriculture and Food industries. Latency period from first exposure to development of symptoms was surprisingly long: between 2 and 20 years and a median of eight years. The time from onset of symptoms to diagnosis was also long for one case (19 years) and a mean of 2 years in the rest of cases. the examination found. Clinical and radiological symptoms led to the assessment of diagnosis of occupational asthma. Mild to severe respiratory insufficiency was discovered throughout the expertise examination and the rate of permanent partial impairment after expert’s assessment was from 30% to 60%.

Discussion and conclusion

In order to reduce the burden of disease and impairment, medical surveillance, quick diagnosis, qualified medical management, and use of workplace prevention measures are crucial. Keywords: Asthma; occupational disease; causal agents; expertise; workplace.
P-487 INVESTIGATION OF LUNG DISORDER BY MICROPLASTIC; SHORT-TERM INHALATION EXPOSURE OF POLYPROPYLENE IN RATS
Authors: Tomonaga Taisuke , Izumi Hiroto , Kawai Naoki , Sato Kazuma , Nishida Chinatsu , Higashi Yasuyuki , Morimoto Toshiki , Higashi Hidenori , Yatera Kazuhiro , Morimoto Yasuo
Published: July 2024

Background

Workers who handle plastics and workers engaged in waste disposal may be exposed to microplastics through the respiratory tract. However, there have been few reports on the biological effects of microplastics in the lungs. In this study, we conducted a short-term inhalation exposure study using rats to evaluate lung disorders with microplastics.

Methods

Inhalation exposure was conducted using 8-week-old male Fischer 344 rats at a low concentration of 2 mg/m3 and a high concentration of 10 mg/m3 of polypropylene fine powder for 6 hours a day, 5 days a week for 4 weeks. Rats were dissected at 3 days, 1 month, and 3 months after inhalation exposure, and bronchoalveolar lavage fluid (BALF) and lung tissue were collected to analyze lung inflammation and lung injury.

Results

An increase in the percentage of neutrophils in BALF was observed at both low and high concentrations 3 days after exposure, and the observation of lung histopathology specimens showed an influx of inflammatory cells in the alveolar space. In the high-concentration group, the number of neutrophils in BALF increased even at 1 month, and lactate dehydrogenase activity, an indicator of lung injury, also showed a sustained increase up to 1 month.

Discussion/Conclusion

In this study, a short-term inhalation exposure to microplastics was conducted. The results showed inflammatory changes in a dose-dependent manner, and inflammatory changes were observed at the exposure of 2 mg/m3 after 3 days of exposure but were very mild. These suggest that the exposure concentration of 2 mg/m3 is close to the threshold for acute effects.
P-497 REVIEW OF LOW DOSE EXPOSURES AND RISK OF ASBESTOSIS: A SYSTEMATIC ANALYSIS
Authors: Bønløkke Jakob , Omland Øyvind , Sherson David , Jacobsen Iben Brock , Bonde Jens Peter , Meyer Harald , Shaker Saher Burhan , Bælum Jesper , Kolstad Henrik , Schlünssen Vivi , Davidsen Jesper Rømhild , Burdorf Alex , Kraus Thomas
Published: July 2024

Introduction

For decades, asbestosis has been associated with inhalation of asbestos fibers in occupational settings. A consensus has emerged around diagnosing asbestosis through CT scan findings combined with documented asbestos exposure, regardless of symptoms. Pathological or histological examination can aid diagnosis in case radiological and exposure information is inconclusive. The relationship between asbestos exposure dose and disease development remains debated. We investigated if cumulative asbestos exposure below 25 fiber-years elevates asbestosis risk.

Methods

Occupational and respiratory medicine experts conducted a systematic review of scientific literature. A comprehensive database search yielded 7824 potentially relevant titles of which 206 articles were reviewed. The final review encompassed 31 original articles reporting associations between cumulative asbestos exposure and parenchymal lung fibrosis based on chest X-rays, CT scans, pathological information, or death certificates.

Results

Of the 31 studies, 11 were considered high-quality with limited risk of bias. Because of large differences in the methods, and only xx studies examined effects below 25 fiber-years, the review was suggestive of, but with limited evidence that an increased risk of parenchymal lung fibrosis (and thus of being diagnosed with asbestosis according to current criteria) occurs below 25 fiber-years.

Discussion

A threshold for cumulative asbestos exposure’s effect on asbestosis could not be identified. Smoking and age were linked to radiological changes suggestive of asbestosis, potentially complicating diagnosis. This comprehensive review enhances our understanding of asbestosis risk factors, informing occupational health policies and practices.

Conclusion

The review provided limited evidence that cumulative exposure below 25 fiber-years elevates risk of asbestosis.
P-498 CAN WORKING WITH PNEUMOTOXIC MEDICATION LEAD TO PULMONARY FIBROSIS IN HEALTH WORKERS? A CASE OF PULMONARY FIBROSIS AFTER A CAREER WITH DAILY HANDLING OF BLEOMYCIN
Authors: Keirsbilck Stephan , De Crem Nico , UZ Wim Wuyts , Boeykens Eva , Nemery Ben , Ronsmans Steven
Published: July 2024

Introduction

Bleomycin, an antitumor antibiotic used to treat malignancies, causes interstitial pulmonary fibrosis in 10% of patients receiving high cumulative dosages intravenously. Bleomycin is a model chemical to induce lung fibrosis in experimental animals. Intralesional injection bleomycin is also used in dermatology to treat recalcitrant warts (without evidence of lung toxicity to the patients).

Methods

A 67-year-old man was referred for pulmonary fibrosis. He was a smoker for about 20 years (1/2 pack/day, cessation in 1990) with an unremarkable medical history, except for arterial hypertension and reflux oesophagitis. He mentioned a slow deterioration of his physical ability and coughing without other respiratory complaints, except for a single episode of haemoptysis and an asymptomatic COVID infection.

Results

HRCT was compatible with nonspecific interstitial pneumonia, showing subpleural reticulation, thickened interlobular septa and ground-glass opacities mainly in posterobasal areas. Lung function showed normal volumes but a decreased diffusing capacity (DLco 65% predicted). Common causes of pulmonary fibrosis (including autoimmune disease, hypersensitivity pneumonitis) were excluded. He had recently retired after a 25-year career as a dermatologist in private practice, during which he had treated, almost every day, patients with warts with intralesional injections of bleomycin using jet injectors. He prepared and administered the medication himself, without taking safety precautions against the inhalation of small droplets generated by the pneumatic jet injection. He is estimated to have handled about 90 mg of bleomycin per year.

Discussion and conclusion

This unique case suggests that repeated occupational exposures to small amounts of airborne bleomycin in dermatological clinical practice may lead to lung fibrosis.
P-503 HEALTH EFFECTS OF DUST IN RURAL COTTAGE INDUSTRIES IN INDIA
Authors: Chandrasekar Sashikala , Ravindran Sudha Rani
Published: July 2024

Introduction

Dust and aerosol exposure affect the health of rural cottage industries workers and the residents near these units. Sericulture and incense sticks (agarbathi) units employ mostly women workers. The objective of this study was to detect prevalence of allergic bronchitis and asthma among workers in these industries and the nearby residents.

Methods

50 sericulture and 50 agarbathi workers working for more than 5 years, and 50 nearby residents, all females aged 30 to 45 years were enrolled for this study with their consent. After general clinical examination and medical history, these participants underwent pulmonary function tests.

Results

Findings in each group of 50 persons showed: Asthma in 4 and allergic bronchitis in 11 sericulture workers. Asthma in 3 and allergic bronchitis in 14 agarbathi workers. Asthma in 1 and allergic bronchitis in 9 nearby residents.

Discussion

Dust and aerosols remain in the workplace and surrounding environment, affecting the workers and nearby residents. Workers are exposed to aerosols when silkworm cocoons are placed in hot water for reeling silk yarn. Workers in cocoon storage places and trading centers are exposed to epithelial dust from silkworm moths and cocoons. Previous studies had shown sericulture workers develop sensitization to silkworm allergens. In manually rolled agarbathi units, workers are exposed to chemicals and dusting powder while mixing ingredients, rolling, and dusting the agarbathis.

Conclusion

Asthma and allergic bronchitis are prevalent in these workers and nearby residents. Mechanization and barriers for dust is not possible in small units. Use of masks is recommended. These industries should be outside residential areas.
O-340 CHANGES IN ATTITUDES TOWARD INFECTION CONTROL MEASURES IN THE WORKPLACE DURING THE COVID-19 PANDEMIC – LONGITUDINAL DATA FROM EMPLOYEES IN GERMANY
Authors: Soeder Jana , Wagner Anke , Neunhöffer Anna T , Martus Peter , Wittich Andrea , Schwille-Kiuntke Juliane , Rieger Monika A , Rind Esther
Published: July 2024

Introduction

Highly regulated working conditions in Germany ensure workers’ occupational safety and health (OSH). Safety culture is associated with safety behavior. Attitudes are associated with health-related behavior intentions. During the COVID-19 pandemic, OSH-measures for SARS-CoV-2-infection control relied on proactive safety behaviors of managers and employees. We explore how employees’ self-reported attitudes toward work-related SARS-CoV-2-infection control measures changed longitudinally.

Methods

We distributed our online survey (ethical approval no.423/2020BO) in autumn 2020 (T0), January 2021 (T1), and autumn 2021 (T2). N=1115 (37% women; age=45.2±11 (mean±SD)) employees of a global supplier of technology and services in Germany participated at least twice and differed not significantly by attitude and socio-demographics regarding the number of participations. 16 items constitute the attitude score toward organizational SARS-CoV-2-infection control measures (5-point Likert-scale: ‘not’-‘very suitable’; Cronbach’s α(T0)=0.86; high value=positive attitude).

Preliminary results

Average attitude scores toward organizational OSH-measures did not change with practical importance between T0 (4.1±0.6), T1 (4.2±0.6; Mann-Whitney-U-test: z=2.56, p=0.01, effect size r=0.06) and T2 (4.0±0.6; z=7.08, p<0.001, r=0.17 (small)). We further explore participants at and above the 80th-percentile as well as at and below the 20th-percentile of change from T0 to T1 (each n=143) and T1 to T2 (each n=134).

Discussion

Using multivariate analyses, we explore factors associated with long-term positive or improving or worsening attitudes toward organizational OSH-measures. Well-developed safety cultures and good framework conditions can help maintain positive attitudes toward OSH-measures or relevantly improve critical attitudes.

Conclusion

Our longitudinal findings highlight the importance of analyzing OSH-framework conditions and safety culture in promoting long-term positive attitudes toward health-protective measures.
P-515 RISK MANAGEMENT AND SAFETY CLIMATE IN HIGH SCHOOL LABORATORIES
Authors: Alvarez-Chavez Clara R , Germán-López Andrea G , Muñoz-Osuna Francisca O , Marín-Ramírez Luz S , Flores-Soto Alma A
Published: July 2024

Introduction

Safety-related accidents in academic laboratories show the need to improve policies, procedures, and practices. School administrators have the responsibility to provide safety conditions to both students and teachers while teachers should educate by example. This study aimed to evaluate risk management and safety climate among laboratory teachers at Sonora High schools (Mexico).

Methods

A 38-item RAMP-T survey adapted from de RAMP methodology (Recognition, Assessment, Minimization and Prepare for Emergencies) and a 20-item CLASS-T (Chemistry Laboratory Safety Survey) were sent to 347 teachers of 107 high schools in Sonora. Protocol and materials were approved by the UNISON Ethics Committee (CEI-UNISON-08/2021). The scale reliability varied from 0.87-0.98 for RAMP-T and from 0.66-0.94 for CLASS-T.

Results

A total of 148 teachers responded to the surveys. RAMP-T scores were above average for all four dimensions. CLASS-T revealed that the safety climate in schools was positive, as is their commitment, leadership, recognition, and practice towards safety. The association between risk management and the safety climate in the laboratory was positive and moderate (r=0.432).

Discussion

Teachers reported managing risks, but it is necessary to reinforce this practice, mainly risk assessment and emergency preparedness. The laboratory safety climate in high schools was positive but still showed opportunities for improvement. The association between safety climate in the laboratory and risk management indicated that a better safety climate in the institution could reinforce risk management, according to the perspective of high school teachers in Sonora.

Conclusions

Active support for laboratory safety by high school administrators could motivate teachers to develop safer laboratory practices.
O-347 LONG WORKING HOURS AND NIGHT WORK BOTH INCREASE THE RISK OF DIABETES IN US WORKERS
Authors: Chen Liwei , Li Jian
Published: July 2024

Introduction

Long working hours (LWH) is a major concern for workers’ health. Although previous studies have linked LWH with a higher risk of diabetes, it is unclear whether the relationship between LWH and diabetes is affected by other working conditions. Thus, we aimed to investigate the interplays between LWH and high night work (HNW) with diabetes risk.

Methods

We included 1,454 workers who were free from diabetes at baseline, using prospective cohort data from the Mid-Life in the United States (MIDUS) study, with 9 years of follow-up. We examined the independent and joint associations of LWH (<54 vs. ≥55 hours/week) and HNW (<15 vs. ≥15 days/year) with diabetes risk, by modified Poisson regressions with adjustment for potential confounders.

Results

During the follow-up period, 103 subjects were identified as incident cases of diabetes, with a cumulative incidence rate of 7.08%. LWH and LNW each was associated with a 60% (adjusted RR=1.60; 95% CI: 1.04, 2.46) and 66% (1.66; 1.05, 2.62) increased risk of diabetes, respectively. Workers with both LWH and HNW exposures had 3 times elevated diabetes risk compared to those with shorter working hours and low night work (3.02; 1.64, 5.58).

Discussion

In a prospective cohort of U.S. workers, we observed independent and additive associations of LWH and HNW with diabetes risk, indicating a new concern in workers’ health.

Conclusion

Our findings suggest that both long working hours and night work could increase the risk of diabetes jointly. Future studies are warranted to confirm our findings and developed strategies to mitigate such risks among workers.
O-350 THE ASSOCIATION BETWEEN IRREGULAR WORKING HOURS AND CARDIOVASCULAR DISEASES IN AN MULTI-ETHNIC POPULATION: THE HELIUS STUDY
Authors: Wijntjens Gilbert W M , Motazedi Ehsan , Franklin Sophia W , Maas Jaap J , van der Ploeg Henrike Galenkamp - , Van den Born Bert-Jan H , Schaafsma Frederieke G
Published: July 2024

Introduction

Shift-work is a riskfactor for cardiovascular diseases (CVD). We studied the association between irregular working hours and CVD in a multi-ethnic population in the Netherlands, and compared this association between various ethnicities.

Methods

Logistic regression was used to study the cross-sectional association between (a history of) irregular working hours and prevalent CVD (self-reported myocardial infarction, dotter/bypass operation or stroke) in 18.746 participants (18–71 years) of Dutch, South-Asian Surinamese, African Surinamese, Ghanaian, Turkish, or Moroccan origin from the Healthy Life in an Urban Setting (HELIUS)-Study. We adjusted for sex, age, occupational level, smoking, alcohol use, physical inactivity, obesity, hypertension, diabetes mellitus, and hyperlipidemia. To study ethnic differences, we tested for interaction between irregular working hours and ethnicity with Dutch as the reference-population, and stratified the analysis by ethnicity.

Results

The prevalence CVD was 17.8% (740 out of 4.159) and 13.9% (2.026 out of 14.587) in the population with and without irregular working hours, respectively. Working irregular hours was associated with CVD (adjusted odds-ratio(OR) 1.18, (95%-confidence interval(CI): 1.07-1.30). Stratified by ethnicity, strongest associations with CVD were found for South-Asian Surinamese (OR 1.39, 95%-CI: 1.11-1.74) and Moroccans (OR 1.38, 95%-CI: 1.07, 1.79). The OR for CVD between individuals with versus without irregular working hours among the South-Asian Surinamese was significantly different from the Dutch (p=0.04).

Discussion and conclusion

The present study demonstrates that working irregular hours is an independent risk factor for CVD in a multi-ethnic population. In particular, individuals from South-Asian Surinamese and Moroccans origin working irregular hours are at increased risk to have developed CVD.
P-520 SALIVARY BIOMARKERS ANALYSIS AND NEUROBEHAVIORAL ASSESSMENT IN NURSES WORKING ROTATION SHIFTS
Authors: Fenga Concettina , Giambò Federica , Vivarelli Silvia , Teodoro Michele , Costa Chiara
Published: July 2024

Introduction

In Europe, one in five workers is employed in night shift work which is essential in several activities, especially the healthcare sector. Night working may be associated with occurrence of sleep disorders or work-related stress, both potentially augmenting the risk of errors and accidents at work. This study examines the presence of neurobehavioral alterations as potential consequence of shift working and concurrent misalignment of the sleep times and circadian rhythms.

Methods

Nurses (n = 102) employed at a University Hospital located in North-Eastern Sicily, Italy, voluntarily participated in this study. During medical surveillance, morning and evening salivary samples were collected, and seven psychodiagnostics questionnaires were administered to all the subjects. Salivary levels of stress-related biomarkers (cortisol and alpha-amylase) and a circadian biomarker (melatonin) were evaluated. Also, several neurobehavioral features were assessed, including depression, anxiety, work-related, and sleep issues.

Results

All examined stress indexes highlighted that a small percentage of the nurses experienced work-related stress. However, a higher percentage of females than males reported mild depressive and anxious symptoms. Also, 76% of nurses consider their sleep quality to be good. Finally, a positive relationship between salivary morning cortisol and depression scale, as well as a negative relationship between salivary morning alpha-amylase and work ability scale, were observed.

Discussion

Based on these results, the integration of subjective questionnaire outcomes and objective salivary biomarker quantification can help to identify workers with increased susceptibility to developing neurobehavioral alterations.

Conclusion

This approach may contribute to ameliorating preventive strategies towards sensitive categories, such as nurses working rotating shifts.
P-529 STUDY OF THE HEALTH PROFILE OF SHIFT WORKERS IN THE PRODUCTION DEPARTMENT OF A FERTILISER INDUSTRY IN INDIA
Authors: Pingle Shyam , Patel Alpesh , Sinha Anish
Published: July 2024

Objectives

The study investigated whether the general and rotating shift workers of the production department of a Fertiliser industry are associated with shift-related health problems/symptoms.

Methodology

This is a Descriptive Cross-sectional study conducted in a Fertiliser industry in Gujarat, India. The study was conducted using a questionnaire, interview and last annual medical check up reports, capturing information about socio-demographic, physical, social, and psychological health problems. A total of 115 out of 128 employees working in the Production department of the industry responded, 39 general shift employees and 76 rotating shift employees.

Results

The results of this study indicated that rotating shift working may be associated with Gastrointestinal diseases (55%), Sleep-related problems (55%), Psychological problems (70%), Lifestyle diseases (32%), and General health symptoms (30%) This study also showed that shift working could be a risk factor for health-related problems as compared to general shift workers. Prevalence of sleep disorders was reported to be much higher (64%) in shift employees than in general shift employees (36%). Prevalence of cases of other diseases including hypertension was also higher in rotating shift employees compared to general shift employees.

Discussion and Conclusion

It appears that rotating shifts are a risk factor for employees’ health perceptions and working in rotation shifts carries a considerable degree of strain on the physiological function of the body. The industry management needs to address the perceptions and health-related problems of employees. It is recommended to discontinue work in fixed shifts and introduce forward rotating shift system after creating appropriate awareness among stakeholders.
P-537 SCREENING AND MANAGEMENT OF ADDICTION TO PSYCHOACTIVE SUBSTANCES IN AN ELECTRICITY, DRINKING WATER AND SANITATION DISTRIBUTION COMPANY
Authors: Andaloussi Jamal , Laraqui Hossini Chakib
Published: July 2024

Introduction

Screening and management of addiction to psychoactive substances in an electricity, drinking water and sanitation distribution company.

Objective

the approach was designed to screen and manage people addicted to one or more of the following psychoactive substances: tobacco, cannabis, alcohol and certain drugs.

Methods

Candidates were either volunteers or designated employees in security positions. The misuse was assessed by specific tests: Fagerstrom,CAST and AUDIT. Motivational interviewing and decision scales completed the study tools. The breathalyzer was used to assess the level of alcohol in exhaled air. Blood test included and urine test (tetrahydrocannabinol and carbohydrate deficient transferrin). The majority of consultations were carried out by an addictologist-psychiatrist AND Medication cognitive-behavioral therapy. Confidentiality and medical secrecy were respected. Medical care was paid for by the employer. The agreement of the social partners was a prerequisite for this action.

Results

67% were volunteers. 12% of the total workforce were treated. 5.6% of addicts were women. 25% suffered from psychiatric pathologies (generalized anxiety disorder, depression, schizophrenia, etc.). At the end of treatment, 47.2% of addicts were abstinent.

Discussion and Conclusion

The Health, Safety and Working Conditions Committee was informed only of the costs and overall results of the approach, which has contributed to improving worker health and safety through: - Raising awareness of the risks of psychoactive substances consumption - Treating addiction - Improving well-being at work. - Preventing occupational injuries and accidents on the road
O-356 OCCUPATIONAL INJURIES AND SEVERITY AMONG WORKERS IN IRON AND STEEL INDUSTRIES IN TANZANIA
Authors: Kabelwa Saumu Shabani
Published: July 2024

Background

Most manufacturing iron and steel industries in Tanzania are not automated, workers are directly involved in various processes such as scrap metals segregation, collection, and addition to the furnace. This situation predisposes them to a hazardous environment which may endanger their health and safety.

Methods

The design was retrospective cross-sectional study using a quantitative approach conducted in 2022 in Tanzania. A sample size of 251 workers from the production line in iron and steel industries were involved in the study. The data were collected by a structured questionnaire modified from Occupational injuries statistics from household surveys and establishment surveys ILO manual. The questionnaire was translated in Swahili language by using back translation and pretested in Dar es Salaam Small Industries Cooperatives. Chi-square test and binary logistic regression were used to identify different predictors of occupational injuries

Results

The Prevalence of 12 months occupational injury was 66.1%. About 61.1% of injured workers were hospitalized for 24 or more working hours. Working years [COR: 0.52, 95% CI: (0.28-0.94))], working days[COR: 0.44, 95% CI: (0.25-0.80))], working hours per week [COR: 4.37, (95% CI: (1.88 -10.17)], and working shift[COR: 0.52, (95% CI: (0.30- 0.90)] were significantly associated factors with prevalence of occupational injury.

Discussion and conclusion

Prevalence of occupational injuries in iron and steel industries is 66.1%, this prevalence is considerable high in comparison with 21.6%, 22%, 38.4% occupational injuries prevalence in iron and steel industries in India, Turkey and Ethiopia respectively. Much effort is needed to eradicate injury occurrence within the industries.
P-539 OCCUPATIONAL HEALTH IN INDIA
Authors: Malhotra Parul
Published: July 2024

Introduction

India, with 1.4 billion people is a land of challenges and opportunities in Occupational health. It contributes 17.5% of the global population and a staggering 25% of the global working population. • Occupational health is an important aspect of public health, especially given the country’s large workforce and diverse industries.

Methods

The factories act was introduced in India in 1948, as amended by the factories(Amendment) ACT, 1987(Act 20 of 1987), served to assist in formulating national policies in India with respect to occupational safety and health in factories and docks, to ensure the safety, health, and welfare of workers. • As per act, the Department of Factories, Boilers, Industrial Safety & Health, is responsible for enforcing occupational safety and health standards in all factories, mines, and docks.

Results

Despite these efforts, occupational health remains a challenge in India, In the unorganized sector, which accounts for a large portion of the country’s workforce. Unsafe working conditions, exposure to hazardous materials, and lack of access to basic health services are just a few of the issues that workers in the unorganized sector face.

Conclusion

Challenges in India 1. Substantial Labor Force in the unorganized sector 2. Insufficient execution of current legislation. 3 Significant amount of occupational illnesses that are unreported 4. A scarcity of proficient and skilled occupational health professionals 5. Multiplicity of statutory controls 6. Lack of interest or concern from stakeholders 7. Outsourcing physicians has diminished the significance of OH 8. Lack of Infrastructure 9. Delay in implementation of national policy on OH.
P-543 WORK-RELATED FACTORS IN POST-COVID SYNDROME
Authors: Magnavita Nicola , Meraglia Igor , Arnesano Gabriele , Merella Marco , Vacca Maria Eugenia
Published: July 2024

Introduction

SARS-CoV-2 infection in some cases is complicated by clinical sequelae known as post-Covid syndrome (PCS). Given the lack of a shared nosographic criterion, it is important to know the distribution of clinical pictures and the relationship of PCS with occupational factors.

Methods

PCS symptoms were collected during health surveillance in the workplace. Stress was studied with the effort/reward imbalance model. Work ability was measured with the Work Ability Index, sleep was studied with the Pittsburgh Sleep Quality Inventory, and mental health with Goldberg’s anxiety and depression scales. The distribution of symptoms was studied by cluster analysis.

Results

In a population of 1378 workers under health surveillance, 164 COVID-19 cases occurred by 2021 and 115 of them (70%) had PCS. Three main clinical pictures were recognized: anosmia/dysgeusia (41% of cases); weakness/tiredness/fatigability (38%); and complex pictures including, in addition to the previous ones, muscle aches, headache, insomnia, dyspnea, tachycardia, and neuropsychological disorders (21%). PCS cases had a significant reduction in work capacity compared with colleagues healed without relics (p<0,05). The occurrence of PCS was significantly associated with poor sleep quality (p<0.05), anxiety (p<0.01) and depression (p<0.01). Work-related stress was not significantly associated with PCS.

Discussion

Although less severe than observed in severe cases of COVID-19 admitted to intensive care unit, PCS in a significant proportion of previously healthy workers may require supportive interventions to regain full work capacity.

Conclusion

Recognizing PCS in workplaces is very important to put in place the necessary measures to protect workers and limit the impact on productivity and health.
P-546 DETERMINANTS OF RETURNING TO WORK AFTER OCCUPATIONAL INJURIES
Authors: Sellami Imen , Feki Afef , Rmadi Nehla , Kotti Nada , Abbes Anwar , Tah Marieme , Meska Ahmed , Masmoudi Mohamed Larbi , Hammami Kaouthar Jmal , Hajjaji Mounira , Hrairi Anouare , Haddar Aicha
Published: July 2024

Introduction

Victims of occupational injuries often reintegrate successfully into the workplace. However, some may encounter difficulties in returning. Thus, identifying factors influencing this process is crucial to prevent an unsuccessful return to work (URTW).

Methods

This cross-sectional study was conducted at the National Health Insurance Fund of Tunisia among victims of occupational injuries. Individual and professional factors have been evaluated through face-to-face questionnaires over a nine-month period. Biomechanical exposure was estimated by the job-exposure matrix “MADE” and social support by the Social Support Scale. Bortner score was used to assess psychological profile. Perceived mental and physical health was evaluated using the short form survey.

Results

A total of 199 injured workers participated. The mean age was 42.73±9.58 years. An URTW was observed in 39.7% of cases. Low social support, biomechanical exposure, the category of blue-collar workers, type A personality, working for long hours, severe injuries, and duration of absence were associated with a URTW. Better perceived mental and physical health protected from worse outcomes. Multiple binary logistic regression identified four factors independently associated with a URTW after occupational injuries: weekly workload, social support, and perceived physical and mental health.

Discussion

The occurrence of URTW had several determinants. Hence, health promotion programs should be enhanced to include safety measures for vulnerable categories by reducing biomechanical exposure in the workplace and enhancing social support.

Conclusion

To limit URTW, collaboration among employees, employers, safety officers, and occupational therapists is always necessary to provide appropriate guidance for vulnerable employees during the process of returning to work.