bluuebunny/crossref_metadata_2025 huggingface dataset:
Clinical trajectories and biomarkers for weight variability in early Parkinson’s disease
Authors: Urso Daniele , van Wamelen Daniel J. , Batzu Lucia , Leta Valentina , Staunton Juliet , Pineda-Pardo José A. , Logroscino Giancarlo , Sharma Jagdish , Ray Chaudhuri K.
Published: August 2022

Unexplained weight changes that occur in Parkinson’s disease (PD), are often neglected and remain a poorly understood non-motor feature in patients with PD. A specific ‘Park-weight’ phenotype with low body weight has been described, and our aim was to evaluate the clinical and prognostic trajectories and biomarkers of weight variability in PD. We evaluated body weight-related biomarkers in 405 de novo PD patients and 187 healthy controls (HC) over a 5-year follow-up period from the PPMI database. Body-weight variability was defined as intra-individual variability in body weight between visits. PD patients were categorized as weight losers, gainers, or patients with stable weight. The differential progression of motor and non-motor clinical variables between groups was explored using linear mixed-effects models. Finally, we estimated longitudinal changes in weight as a function of baseline and longitudinal striatal presynaptic dopaminergic transporter imaging. PD patients presented a greater weight variability compared to HC (p = 0.003). Patients who developed weight loss had lower CSF amyloid-beta 1–42 (p = 0.009) at baseline. In addition, patients with weight loss showed a faster cognitive decline (p = 0.001), whereas patients with weight gain showed a slower motor progression (p = 0.001), compared to patients with stable weight. Baseline right striatal denervation was a predictor of weight variability in both PD patients and HC (p < 0.001). Similarly, weight variability in PD patients was associated with the progression of right striatal denervation (p < 0.001). Weight variability and specifically weight loss are more frequent in PD compared to HC, and are associated with specific motor, non-motor and cognitive progression patterns. A greater CSF amyloid burden was present at baseline in patients with subsequent weight loss. Presynaptic dopaminergic imaging in the right striatum may serve as a predictor of future weight changes in PD and HC.
Compilation of longitudinal gut microbiome, serum metabolome, and clinical data in acute myeloid leukemia
Authors: Rashidi Armin , Ebadi Maryam , Rehman Tauseef Ur , Elhusseini Heba , Halaweish Hossam , Kaiser Thomas , Holtan Shernan G. , Khoruts Alexander , Weisdorf Daniel J. , Staley Christopher
Published: August 2022

Induction chemotherapy for patients with acute myeloid leukemia (AML) is a unique clinical scenario. These patients spend several weeks in the hospital, receiving multiple antibiotics, experiencing gastrointestinal mucosal damage, and suffering severe impairments in their immune system and nutrition. These factors cause major disruptions to the gut microbiota to a level rarely seen in other clinical conditions. Thus, the study of the gut microbiota in these patients can reveal novel aspects of microbiota-host relationships. When combined with the circulating metabolome, such studies could shed light on gut microbiota contribution to circulating metabolites. Collectively, gut microbiota and circulating metabolome are known to regulate host physiology. We have previously deposited amplicon sequences from 566 fecal samples from 68 AML patients. Here, we provide sample-level details and a link, using de-identified patient IDs, to additional data including serum metabolomics (260 samples from 36 patients) and clinical metadata. The detailed information provided enables comprehensive multi-omics analysis. We validate the technical quality of these data through 3 examples and demonstrate a method for integrated analysis.
Investigation of memory-enhancing effects of Streptococcus thermophilus EG007 in mice and elucidating molecular and metagenomic characteristics using nanopore sequencing
Authors: Kim Hyaekang , Jeon Soomin , Kim Jina , Seol Donghyeok , Jo JinChul , Cho Seoae , Kim Heebal
Published: August 2022

Over the past decades, accumulating evidences have highlighted the gut microbiota as a key player in the brain functioning via microbiota–gut–brain axis, and accordingly, the beneficial role of several probiotic strains in cognitive ability also have been actively investigated. However, the majority of the research have demonstrated the effects against age-related cognitive decline or neurological disease. To this end, we aimed to investigate lactic acid bacteria strains having beneficial effects on the cognitive function of healthy young mice and elucidate underlying characteristics by carrying out nanopore sequencing-based genomics and metagenomics analysis. 8-week consumption of Streptococcus thermophilus EG007 demonstrated marked enhancements in behavior tests assessing short-term spatial and non-spatial learning and memory. It was revealed that EG007 possessed genes encoding various metabolites beneficial for a health condition in many aspects, including gamma-aminobutyric acid producing system, a neurotransmitter associated with mood and stress response. Also, by utilizing 16S–23S rRNA operon as a taxonomic marker, we identified more accurate species-level compositional changes in gut microbiota, which was increase of certain species, previously reported to have associations with mental health or down-regulation of inflammation or infection-related species. Moreover, correlation analysis revealed that the EG007-mediated altered microbiota had a significant correlation with the memory traits.
Assessment of thermal distribution through an inclined radiative-convective porous fin of concave profile using generalized residual power series method (GRPSM)
Authors: Varun Kumar R. S. , Sowmya G. , Jayaprakash M. C. , Prasannakumara B. C. , Khan M. Ijaz , Guedri Kamel , Kumam Poom , Sitthithakerngkiet Kanokwan , Galal Ahmed M.
Published: August 2022

The thermal distribution in a convective-radiative concave porous fin appended to an inclined surface has been examined in this research. The equation governing the temperature and heat variation in fin with internal heat generation is transformed using non-dimensional variables, and the resulting partial differential equation (PDE) is tackled using an analytical scheme, generalized residual power series method (GRPSM). Moreover, a graphical discussion is provided to examine the consequence of diverse non-dimensional variables including the parameters of convection-conduction, ambient temperature, radiation, heat generation, and porosity effect on the thermal field of the fin. Also, a graph is plotted to analyze the variations in unsteady temperature gradient using the finite difference method (FDM) and generalized residual power series method (GRPSM). The major result of this investigation unveils that as the convection-conduction parameter scale upsurges, the distribution of temperature in the fin diminishes. For the heat-generating parameter, the thermal distribution inside the fin increases.
Understanding hesitancy with revealed preferences across COVID-19 vaccine types
Authors: Kutasi Kristóf , Koltai Júlia , Szabó-Morvai Ágnes , Röst Gergely , Karsai Márton , Biró Péter , Lengyel Balázs
Published: August 2022

Many countries have secured larger quantities of COVID-19 vaccines than their population is willing to take. The abundance and the large variety of vaccines created not only an unprecedented intensity of vaccine related public discourse, but also a historical moment to understand vaccine hesitancy better. Yet, the heterogeneity of hesitancy by vaccine types has been neglected in the existing literature so far. We address this problem by analysing the acceptance and the assessment of five vaccine types. We use information collected with a nationally representative survey at the end of the third wave of the COVID-19 pandemic in Hungary. During the vaccination campaign, individuals could reject the assigned vaccine to wait for a more preferred alternative that enables us to quantify revealed preferences across vaccine types. We find that hesitancy is heterogenous by vaccine types and is driven by individuals’ trusted source of information. Believers of conspiracy theories are more likely to evaluate the mRNA vaccines (Pfizer and Moderna) unacceptable. Those who follow the advice of politicians are more likely to evaluate vector-based (AstraZeneca and Sputnik) or whole-virus vaccines (Sinopharm) acceptable. We argue that the greater selection of available vaccine types and the free choice of the individual are desirable conditions to increase the vaccination rate in societies.
Construction of a novel signature and prediction of the immune landscape in gastric cancer based on necroptosis-related genes
Authors: Li Zhengtian , Yang Wenkang , Liu Dejun , Ye Weizheng , Du Gang , Li Xi
Published: August 2022

Necroptosis, a type of programmed cell death, has become a potential therapeutic target for solid tumors. Nevertheless, the potential roles of necroptosis-related genes (NRGs) in gastric cancer (GC) remain unknown. The objective of the present study was to create a necroptosis-related prognostic signature that can provide more accurate assessment of prognosis in GC. Using The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) data, we identified differentially expressed NRGs. Univariate analysis and Lasso regression were performed to determine the prognostic signature. Risk scores were calculated and all GC patients were divided into high- and low-risk score group according to the median risk score value. The robustness of this signature was externally validated with data from GSE84437 cohort (n = 431). Survival analysis revealed high-risk score patients had a worse prognosis. Results evidenced that the signature was an independent prognosis factor for survival. Single-sample sequence set enrichment analysis (ssGSEA) exhibited different enrichment of immune cells and immune-related pathways in the two risk groups. Furthermore, a predictive nomogram was generated and showed excellent predictive performance based on discrimination and calibration. In addition, the risk score positively correlated with tumor mutational burden and was associated with sensitivity to multiple anti-cancer drugs. Overall, our work demonstrates a close relationship between necroptosis and the prognosis of GC. The signature we constructed with potential clinical application value, can be used for prognosis prediction and being a potential therapeutic responses indicator in GC patients.
Last glacial loess dynamics in the Southern Caucasus (NE-Armenia) and the phenomenon of missing loess deposition during MIS-2
Authors: Wolf Daniel , Lomax Johanna , Sahakyan Lilit , Hovakimyan Hayk , Profe Jörn , Schulte Philipp , von Suchodoletz Hans , Richter Christiane , Hambach Ulrich , Fuchs Markus , Faust Dominik
Published: August 2022

The Marine Isotope Stage (MIS) 2 is considered the coldest, driest and stormiest period during the last Glacial-Interglacial cycle in large parts of Eurasia. This resulted from strongly decreased northern hemisphere temperature and related maximum extension of northern ice sheets that strongly reinforced large-scale circulation modes such as westerlies and East Asian Winter Monsoon driven by the Siberian High. Normally, this intensified circulation is reflected by maximum loess deposition in numerous loess regions spanning Europe and Asia. However, here we present a new loess record from the Caucasus region in NE-Armenia providing evidence in support of heavily reduced or even lacking loess formation during the MIS-2. Owing to implementations of comprehensible luminescence dating work and a provenance survey using rock magnetic and geochemical data, we are able to define distinct loess formation phases and to retrace sediment transport pathways. By comparing our results to other Eurasian palaeo-records, we unveil general atmospheric circulation modes that are most likely responsible for loess formation in the Southern Caucasus. Moreover, we try to test different scenarios to explain lacking loess formation during MIS-2. In line with other archive information, we suggest that loess formation was hampered by higher regional moisture conditions caused by a southward-shift of westerlies and renewed moisture absorption over the Black Sea. Our results show that modifications of MIS-2 circulation modes induced a very heterogeneous moisture distribution, particularly in the lower mid-latitudes of Eurasia producing a juxtaposition of very dry (morphodynamically active) and moderately dry (morphodynamically stable) areas.
Evolving norms: social media data analysis on parks and greenspaces perception changes before and after the COVID 19 pandemic using a machine learning approach
Authors: Park Sohyun , Kim Seungman , Lee Jaehoon , Heo Biyoung
Published: August 2022

This study provides a novel approach to understand human perception changes in their experiences of and interactions with public greenspaces during the early months of COVID-19. Using social media data and machine learning techniques, the study delivers new understandings of how people began to feel differently about their experiences compared to pre-COVID times. The study illuminates a renewed appreciation of nature as well as an emerging but prominent pattern of emotional and spiritual experiences expressed through a social media platform. Given that most park and recreational studies have almost exclusively examined whether park use increased or decreased during the pandemic, this research provides meaningful implications beyond the simple extensional visit pattern and lends weight to the growing evidences on changing perceptions over and the positive psychological impacts of nature. The study highlights the preeminent roles parks and greenspaces play during the pandemic and guides a new direction in future park development to support more natural elements and nature-oriented experiences from which emotional and spiritual well-being outcomes can be drawn.
Modifying the yeast very long chain fatty acid biosynthetic machinery by the expression of plant 3-ketoacyl CoA synthase isozymes
Authors: Stenback Kenna E. , Flyckt Kayla S. , Hoang Trang , Campbell Alexis A. , Nikolau Basil J.
Published: August 2022

Eukaryotes express a multi-component fatty acid elongase to produce very long chain fatty acids (VLCFAs), which are building blocks of diverse lipids. Elongation is achieved by cyclical iteration of four reactions, the first of which generates a new carbon–carbon bond, elongating the acyl-chain. This reaction is catalyzed by either ELONGATION DEFECTIVE LIKE (ELO) or 3-ketoacyl-CoA synthase (KCS) enzymes. Whereas plants express both ELO and KCS enzymes, other eukaryotes express only ELOs. We explored the Zea mays KCS enzymatic redundancies by expressing each of the 26 isozymes in yeast strains that lacked endogenous ELO isozymes. Expression of the 26 maize KCS isozymes in wild-type, scelo2 or scelo3 single mutants did not affect VLCFA profiles. However, a complementation screen of each of the 26 KCS isozymes revealed five that were capable of complementing the synthetically lethal scelo2; scelo3 double mutant. These rescued strains express novel VLCFA profiles reflecting the different catalytic capabilities of the KCS isozymes. These novel strains offer a platform to explore the relationship between VLCFA profiles and cellular physiology.
The effect of supplementary light on the photosynthetic apparatus of strawberry plants under salinity and alkalinity stress
Authors: Shamsabad Mohammad Reza Malekzadeh , Esmaeilizadeh Majid , Roosta Hamid Reza , Dehghani Mohammad Reza , Dąbrowski Piotr , Kalaji Hazem M.
Published: August 2022

Considering the destructive effect of stresses on the photosynthetic apparatus of plants and the important role of light in photosynthesis, we investigated the effect of complementary light on the photosynthetic apparatus under salinity and alkalinity stress conditions. Light-emitting diodes (LEDs) in monochromatic blue (460 nm), monochromatic red (660 nm), dichromatic blue/red (1:3), white/yellow (400–700 nm) at 200 μmol m−2 S−1, and without LED treatment were used. The stress treatments were in three stages: Control (no stress), Alkalinity (40 mM NaHCO3), and Salinity (80 mM NaCl). Our results showed that salinity and alkaline stress reduced CO2 assimilation by 62.64% and 40.81%, respectively, compared to the control treatment. The blue light spectrum had the highest increase in water use efficiency (54%) compared to the treatment without supplementary light. Under salinity and alkalinity stress, L, K, and H bands increased and G bands decreased compared to the control treatment, with blue/red light causing the highest increase in L and K bands under both stress conditions. In salinity and alkalinity stress, white/yellow and blue/red spectra caused the highest increase in H bands. Complementary light spectra increased the G band compared to the treatment without complementary light. There was a significant decrease in power indices and quantum power parameters due to salt and alkalinity stress. The use of light spectra, especially blue, red, and blue/red light, increased these parameters compared with treatment without complementary light. Different light spectra have different effects on the photosynthetic apparatus of plants. It can be concluded that using red, blue spectra and their combination can increase the resistance of plants to stress conditions and be adopted as a strategy in planting plants under stress conditions.
Formulation, characterization and cellular toxicity assessment of a novel bee-venom microsphere in prostate cancer treatment
Authors: El-Didamony Samia E. , Amer Reham I. , El-Osaily Ghada H.
Published: August 2022

Bee venom (B.V.) is a toxin produced naturally by honey bees with several toxic and therapeutic efficacies. It is used in the treatment of different cancer kinds like renal, hepatic, and prostate cancer. Due to its protein nature, it is degraded in the upper gastrointestinal tract. Colon-targeted drug delivery systems represent a useful tool to protect B.V. from degradation and can be administered orally instead of I.V. infusion and traditional bee stinging. In the present study, B.V. loaded enteric-coated cross-linked microspheres were prepared by emulsion cross-linking method. Percentage yield, entrapment efficiency %, swelling degree, and in-vitro release are evaluated for prepared microspheres. Free B.V., optimized microspheres formula (F3), and doxorubicin cytotoxic effects were tested by MTT assay. Results concluded that free B.V. was more effective against the growth of human prostate adenocarcinoma (PC3) cells followed by optimized microspheres than doxorubicin. But both free B.V. and doxorubicin have a cytotoxic effect on normal oral epithelial cells (OEC). According to flow cytometric analysis, the optimized microsphere formula induced apoptosis and reduced necrosis percent at IC50 concentration. Furthermore, microspheres did not affect the viability of OEC. These results revealed that microspheres have a degree of specificity for malignant cells. Therefore, it seems that this targeted formulation could be a good candidate for future clinical trials for cancer therapy.
Gun identification from gunshot audios for secure public places using transformer learning
Authors: Nijhawan Rahul , Ansari Sharik Ali , Kumar Sunil , Alassery Fawaz , El-kenawy Sayed M.
Published: August 2022

Increased mass shootings and terrorist activities severely impact society mentally and physically. Development of real-time and cost-effective automated weapon detection systems increases a sense of safety in public. Most of the previously proposed methods were vision-based. They visually analyze the presence of a gun in a camera frame. This research focuses on gun-type (rifle, handgun, none) detection based on the audio of its shot. Mel-frequency-based audio features have been used. We compared both convolution-based and fully self-attention-based (transformers) architectures. We found transformer architecture generalizes better on audio features. Experimental results using the proposed transformer methodology on audio clips of gunshots show classification accuracy of 93.87%, with training loss and validation loss of 0.2509 and 0.1991, respectively. Based on experiments, we are convinced that our model can effectively be used as both a standalone system and in association with visual gun-detection systems for better security.
Effective deep learning for oral exfoliative cytology classification
Authors: Sukegawa Shintaro , Tanaka Futa , Nakano Keisuke , Hara Takeshi , Yoshii Kazumasa , Yamashita Katsusuke , Ono Sawako , Takabatake Kiyofumi , Kawai Hotaka , Nagatsuka Hitoshi , Furuki Yoshihiko
Published: August 2022

The use of sharpness aware minimization (SAM) as an optimizer that achieves high performance for convolutional neural networks (CNNs) is attracting attention in various fields of deep learning. We used deep learning to perform classification diagnosis in oral exfoliative cytology and to analyze performance, using SAM as an optimization algorithm to improve classification accuracy. The whole image of the oral exfoliation cytology slide was cut into tiles and labeled by an oral pathologist. CNN was VGG16, and stochastic gradient descent (SGD) and SAM were used as optimizers. Each was analyzed with and without a learning rate scheduler in 300 epochs. The performance metrics used were accuracy, precision, recall, specificity, F1 score, AUC, and statistical and effect size. All optimizers performed better with the rate scheduler. In particular, the SAM effect size had high accuracy (11.2) and AUC (11.0). SAM had the best performance of all models with a learning rate scheduler. (AUC = 0.9328) SAM tended to suppress overfitting compared to SGD. In oral exfoliation cytology classification, CNNs using SAM rate scheduler showed the highest classification performance. These results suggest that SAM can play an important role in primary screening of the oral cytological diagnostic environment.
Sustained decline in tobacco purchasing in Denmark during the COVID-19 pandemic
Authors: Fosgaard Toke R. , Pizzo Alice , Sadoff Sally
Published: August 2022

Background

An estimated 8 million people die every year due to tobacco use. The COVID-19 pandemic has increased the health consequences of smoking, which is a leading risk factor for more severe COVID-19 symptoms, hospitalization, and death. The pandemic has also led to reductions in physical activity, increases in stress and declines in mental well-being, all factors commonly associated with triggering higher tobacco use.

Methods

Using a longitudinal data set of purchasing behavior from 2019–2020 among a national sample of the Danish population (n = 4042), we estimate changes in tobacco use during the COVID-19 pandemic. Our analysis compares tobacco purchases prior to the pandemic to purchases during the pandemic, at the individual level. We also examine effects within subgroups based on smoking behavior in 2019 prior to the pandemic. We estimate effects for smokers and non-smokers and, within smokers, for occasional smokers and regular smokers.

Results

We find large, sustained decreases in tobacco purchases during COVID-19. We estimate that weekly tobacco purchase rates decline by 24% and average quantities decline by 12% during the period spanning the onset of the pandemic in March 2020 through the end of the year. The declines are driven by regular smokers with little change in behavior among nonsmokers and increases in purchases among occasional smokers. Among regular smokers, purchase rates decline by about 30%, tobacco purchases decline by about 20% and quitting rates increase by about 10 percentage points.

Conclusions

Our results suggest that the COVID-19 pandemic could lead to sustained reductions in smoking.
Ultrasensitive detection of multiple Alzheimer's disease biomarkers by SERS-LFA
Authors: Zhan Yuanbao , Fei Ruihua , Lu Yu , Wan Yu , Wu Xuming , Dong Jian , Meng Dianhuai , Ge Qinyu , Zhao Xiangwei
Published: August 2022

A lateral flow assay, based on Surface-enhanced Raman scattering nanotags (SERS-LFA), is proposed for simultaneous quantification of multiple AD biomarkers with high sensitivity.
Comparison of signal enhancement strategies for carbamazepine detection in undiluted human saliva using an electrochemical sensor with stencil-printed carbon electrodes
Authors: Wentland Lael , Downs Corey , Fu Elain
Published: August 2022

We have demonstrated an electrochemical assay that can quantify carbamazepine in a background of human saliva over the range of therapeutically-relevant concentrations using sodium dodecyl sulfate and incubation.
Amide bond hydrolysis of peptoids
Authors: Ghosh Pritam , Ruan Guilin , Fridman Natalia , Maayan Galia
Published: August 2022

A chiral non-coordinating substitution at N-terminal end within peptoids facilitates regio-selective amide bond hydrolysis mediated by a transition metal ion and/or an acidic buffer as evident by X-ray crystallographic analysis, supported by ESI-MS.
Isostructurality in amino molecular salts of two dicarboxylic acids driven by noncovalent synthons
Authors: Medishetty Raghavender , Ekka Akansha , Mulijanto Caroline Evania , Tandiana Rika , Vittal Jagadese J.
Published: August 2022

Isostructurality was investigated for the molecular salts of two carboxylates. The luminescence properties of the solid solutions of 4apy salts of these carboxylates indicate that this property can be used to fine tune the physical properties.
Molecular niobium(v) complexes with mononuclear {Nb1} and dinuclear oxo species {Nb2O} connected through aryl di- or tetra-carboxylate linker
Authors: Andriotou Despoina , Duval Sylvain , Trivelli Xavier , Volkringer Christophe , Loiseau Thierry
Published: August 2022

Di- or tetracarboxylic acid ligands were used to isolate molecular coordination complexes containing the association of several mononuclear {Nb1} moiety and dinuclear {Nb2O} niobium(v) polyoxo clusters.
Anharmonic IR spectra of solvated ammonium and aminium ions: resemblance between water and bisulfate solvations
Authors: Lin Chih-Kai , Kuo Jer-Lai
Published: August 2022

Ammonium/aminium cations solvated by either water molecules or bisulfate anions show resemblance in their vibrational spectra, indicating a common anharmonic coupling mechanism.
Quantum coherence in molecular photoionization
Authors: Ruberti Marco , Patchkovskii Serguei , Averbukh Vitali
Published: August 2022

Onset, decay, and control of ultrafast quantum coherence in many-electron systems is in the focus of interest of attosecond physics. We discuss electronic and nuclear dynamics affecting it, and outline directions for future study.
Dissociative electron attachment dynamics of carbon disulfide and violation of axial recoil approximation near 6 eV resonance
Authors: Paul Anirban , Nandi Dhananjay
Published: August 2022

Electron attachment occurs at linear geometry of CS2 forming TNI. This TNI state undergoes bending and stretching before dissociation takes place. Bond formation is followed by bond breaking in the case of S2− formation.
Rhodium-based half-Heusler alloys as thermoelectric materials
Authors: Jaishi Dhurba R. , Bati Sujit , Sharma Nileema , Karki Bishnu , Belbase Bishnu P. , Ghimire Madhav Prasad
Published: August 2022

Thermoelectric phenomena provides an alternative for power generation and refrigeration. Half-Heusler are excellent candidates for use in thermoelectric devices.
The mechanism of direct reductive amination of aldehyde and amine with formic acid catalyzed by boron trifluoride complexes: insights from a DFT study
Authors: Li Zhewei , Zhang Huili , Tan Tianwei , Lei Ming
Published: August 2022

A volcano diagram of BF3 catalytic species and their activities was proposed for the DRA of aldehyde and amine with formic acid.
Disproportional surface segregation in ligand-free gold–silver alloy solid solution nanoparticles, and its implication for catalysis and biomedicine
Authors: Stein Frederic , Kohsakowski Sebastian , Martinez-Hincapie Ricardo , Reichenberger Sven , Rehbock Christoph , Colic Viktor , Guay Daniel , Barcikowski Stephan
Published: August 2022

This study provides novel insight into the surface chemistry of laser-ablated organic-ligand-free gold–silver alloy nanoparticles via extensive electrochemical characterization.
Photoredox-catalyzed regio- & stereoselective C(sp2)–H cyanoalkylation of enamides with cycloketone oximes via selective C–C bond cleavage/radical addition cascade
Authors: Guan Ting , Guo Jing-Yu , Zhang Qing-Hong , Xu Xin-Wen , Yu Xiao-Yu , Zhang Yu , Zhao Kai
Published: August 2022

A visible-light-induced regio- and stereoselective C(sp2)–H coupling reaction of enamides with cycloketone oximes is developed under mild and environmentally-friendly conditions.
A general electrochemical strategy for upcycling polyester plastics into added-value chemicals by a CuCo2O4catalyst
Authors: Liu Fulai , Gao Xutao , Shi Rui , Tse Edmund C. M. , Chen Yong
Published: August 2022

A general and efficient electro-reforming strategy was demonstrated to selectively convert polyester plastics into added-value chemicals at the anode catalyzed by a CuCo2O4/Ni foamcatalyst while generating H2at the cathode under mild conditions.
Quantitative brain-derived neurotrophic factor lateral flow assay for point-of-care detection of glaucoma
Authors: Wu Yue , Hu Yubing , Jiang Nan , Anantharanjit Rajeevan , Yetisen Ali K. , Cordeiro M. Francesca
Published: August 2022

We develop a quantitative lateral flow assay (LFA) device that is able to measure the tear level of brain derived neurotrophic factor (BDNF). The device shows great potential to serve as an ideal platform for early detection of glaucoma.
Synthesis and characterization of all-inorganic (CsPbBr3) perovskite single crystals
Authors: Gupta Ramashanker , Datt Ram , Barthwal Swapnil , Sharma Harshit , Pandey Animesh , Deka Ridip , Sarkar Pranjit , Husale Sudhir , Srivastava Ritu , Gupta Vinay , Arya Sandeep , Pathak Sandeep
Published: August 2022

This work investigates the synthesis of Cesium (Cs) based all-inorganic (CsPbBr3) perovskite single crystals (PSCs) at low temperatures (45 °C) for application in photosensitive devices.
Dependence of charge carrier transport on molecular relaxations in glassy poly(3-hexylthiophene-2,5-diyl) (P3HT)
Authors: Gao Zhaojing , Reali Manuel , Yelon Arthur , Santato Clara
Published: August 2022

A positive effect of molecular relaxations and movement of the molecular backbone and chain segments is reported on charge carrier transport in glassy poly(3-hexylthiophene-2,5-diyl). Mechanisms are proposed, above and below the glass transition temperature.
‘Template-free’ synthesis of self-assembled micro-spikes resulting in ‘sea-urchin’-like carbon structures for suppressing electromagnetic radiation
Authors: M. P. Vidyashree , Sushmita Kumari , M. K. Kokila , Bose Suryasarathi
Published: August 2022

We report the facile ‘template-free’ synthesis of self-assembled ‘micro-spikes’, resulting in sea-urchin-like carbon structures that can suppress incoming electromagnetic (EM) radiation, which is not achievable with conventional flake-type dispersed composites.
Extraction of parabens from personal care products using a pH-responsive hydrophobic deep eutectic solvent: experimental design and COSMO-RS evaluations
Authors: Fattahi Nazir , Hashemi Beshare , Shiri Fereshteh , Shamsipur Mojtaba , Babajani Nasrin
Published: August 2022

A pH-responsive hydrophobic deep eutectic solvent is used for the extraction of parabens from different personal care products.
Efficient synthesis of boronate affinity-based catecholamine-imprinted magnetic nanomaterials for trace analysis of catecholamine in human urine
Authors: Li Daojin , Tang Na , Wang Yipei , Zhang Zixin , Ding Yihan , Tian Xiping
Published: August 2022

Catecholamines, a class of cis-diol-containing compounds, play a major role in the central nervous system.
FeMo–N nanosheet arrays supported on nickel foam for efficient electrocatalytic N2 reduction to NH3 under ambient conditions
Authors: Jiang Kun , Li Kai , Li Shuirong , Li Yan , Li Tao , Liu Yun-Quan , Wang Duo , Ye Yueyuan
Published: August 2022

The N content in the M–N bond is closely related to the catalytic activity and greatly improves the NRR performance.
Size-dependence of fullerene-like confinement in catalytic methanol cracking
Authors: Wang Wannan , Ren Rui-Peng , Lv Yong-Kang
Published: August 2022

In this work, the cracking mechanism of CH3OH on fullerene-like surfaces of different sizes is investigated by DFT. The study shows that the activity of CH3OH cracking decreases with the increase of Cu@CnB8 size.
Transition from lamellar to nanostructure mesophases in azobenzene-based hockey-stick polycatenars
Authors: Alaasar Mohamed , Cai Xiaoqian , Cao Yu , Liu Feng
Published: August 2022

Tuning from 1D to 3D mesophases by alkyl chain engineering. Multichain π-conjugated hockey-stick molecules form lamellar SmA and meso-structure Ia3̄d with continuous networks. The effect of the position of the central bent-core unit on helical self-assembly is discussed.
Facile synthesis of MOF-808/AgI Z-scheme heterojunction with improved photocatalytic performance for the degradation of tetracycline hydrochloride under simulated sunlight
Authors: Wang Yingdi , Lin Liangliang , Dong Yuming , Liu Xiang
Published: August 2022

The MOF-808/AgI Z-scheme heterojunction expanded the light absorption range and promoted the separation of electron–hole pairs, thus enhancing the photocatalytic activity.
Epoxy functionalized cycloolefin polymers by ring-opening metathesis polymerization
Authors: So Jongho , Cho Eun Seon , Kim Sang Youl
Published: August 2022

Functional COPs by ROMP and post-polymerization modification.
Modulated electronic structure of Pd nanoparticles on Mg(OH)2 for selective benzonitrile hydrogenation into benzylamine at a low temperature
Authors: Zhang Mingkai , Zou Yong , Zhang Sai , Qu Yongquan
Published: August 2022

Pd nanoparticles with enriched electronic density anchored on Mg(OH)2 realize selective benzonitrile hydrogenation to benzylamine at low temperature in the absence of additives, in an atom-economical and green approach for synthesis of highly value-added primary amines.
Electrochemically-initiated intramolecular 1,2-amino oxygenation of alkynes: facile access to formyl- and acyl-substituted indolizines
Authors: Yang Qi-Liang , Ma Rui-Cong , Li Zhi-Hao , Li Wan-Wan , Qu Gui-Rong , Guo Hai-Ming
Published: August 2022

An environmentally benign electrooxidative approach to the intramolecular aminooxygenation of alkynes through an electrophilic cyclization reaction has been developed, providing an efficient approach toward diverse formyl- and acyl-substituted indolizines.
Fabrication of a graphene-based sensor to detect the humidity and the temperature of a metal body with imprecise data analysis
Authors: Afzal Usama , Aslam Muhammad , Afzal Fatima , Maryam Kanza , Ahmad Naveed , Zafar Qayyum , Farooq Zahid
Published: August 2022

Graphene is a 2D material with remarkable properties.
Synthesis, antitumor activity, 3D-QSAR and molecular docking studies of new iodinated 4-(3H)-quinazolinones 3N-substituted
Authors: Pérez-Fehrmann Marcia , Kesternich Víctor , Puelles Arturo , Quezada Víctor , Salazar Fernanda , Christen Philippe , Castillo Jonathan , Cárcamo Juan Guillermo , Castro-Alvarez Alejandro , Nelson Ronald
Published: August 2022

New iodinated 4-(3H)-quinazolinones 3N-substituted with antitumor activity and 3D-QSAR and molecular docking studies as dihydrofolate reductase (DHFR) inhibitors.
Fluoride-bridged dinuclear dysprosium complex showing single-molecule magnetic behavior: supramolecular approach to isolate magnetic molecules
Authors: Wu Dong-Fang , Takahashi Kiyonori , Fujibayashi Masaru , Tsuchiya Naoto , Cosquer Goulven , Huang Rui-Kang , Xue Chen , Nishihara Sadafumi , Nakamura Takayoshi
Published: August 2022

(Na+)(benzo[18]crown-6) forms a bamboo-like supramolecular architecture within the crystal. Dinuclear Dy complexes with polyoxometalate ligands embedded between bamboo nodes exhibited a clear single-molecule magnet (SMM) response.
Correction: Lipid-based nanoparticles for psoriasis treatment: a review on conventional treatments, recent works, and future prospects
Authors: Mohd Nordin Ummu Umaimah , Ahmad Noraini , Salim Norazlinaliza , Mohd Yusof Nor Saadah
Published: August 2022

Correction for ‘Lipid-based nanoparticles for psoriasis treatment: a review on conventional treatments, recent works, and future prospects’ by Ummu Umaimah Mohd Nordin et al., RSC Adv., 2021, 11, 29080–29101, https://doi.org/10.1039/D1RA06087B.
Gradient copolymersversusblock copolymers: self-assembly in solution and surface adsorption
Authors: Coldstream Jonathan G. , Camp Philip J. , Phillips Daniel J. , Dowding Peter J.
Published: August 2022

Coarse-grained molecular dynamics simulations reveal that the molecular conformations, self-assembly, and surface adsorption of block, gradient, and statistical copolymers show different sensitivities to temperature.
Unveiling adsorption generality in polymeric macromolecules
Authors: Corsi Pietro , De Filippo Carlo Andrea , Del Galdo Sara , Capone Barbara
Published: August 2022

This work unveils a general law for adsorption within macromolecules of various shapes and architectures, setting an important step forward in the design of nanomaterials with tunable and controllable properties.
Revealing and magnifying interfacial effects between ruthenium and carbon supports for efficient hydrogen evolution
Authors: Jiang Yongjun , Huang Ting-Wei , Chou Hsuan-Lien , Zhou Lihui , Lee Sheng-Wei , Wang Kuan-Wen , Dai Sheng
Published: August 2022

Ru has been considered as a highly efficient material for the hydrogen evolution reaction (HER) and becomes one of the promising alternatives to Pt owing to its relatively low price and similar hydrogen bonding strength.
Edge effect-modulated exciton dissociation and charge transfer in porous ultrathin tubular graphitic carbon nitride for boosting photoredox activity
Authors: Xing Weinan , Ma Fang , Li Zongjun , Wang Ao , Liu Mingxia , Han Jiangang , Wu Guangyu , Tu Wenguang
Published: August 2022

The grafting of tunable cysteine units in porous ultrathin tubular CN is designed to effectively relax photoinduced excitons into electrons and holes and accelerate charge transfer from CN into active sites for improved photocatalytic activity.
Correction: Influence of Y-substitution on phase composition and proton uptake of self-generated Ba(Ce,Fe)O3−δ–Ba(Fe,Ce)O3−δ composites
Authors: Berger Christian , Bucher Edith , Merkle Rotraut , Nader Christina , Lammer Judith , Grogger Werner , Maier Joachim , Sitte Werner
Published: August 2022

Correction for ‘Influence of Y-substitution on phase composition and proton uptake of self-generated Ba(Ce,Fe)O3−δ–Ba(Fe,Ce)O3−δ composites’ by Christian Berger et al., J. Mater. Chem. A, 2022, 10, 2474–2482, https://doi.org/10.1039/D1TA07208K.
Targeted NIR-responsive theranostic immuno-nanomedicine combined TLR7 agonist with immune checkpoint blockade for effective cancer photothermal immunotherapy
Authors: Yasothamani Vellingiri , Vivek Raju
Published: August 2022

Nanomedicine with immunotherapy offers opportunities to target cancer in an effective manner; however, it remains challenging.
An artificial light-harvesting system with sequential energy transfer for information dual encryption and anticounterfeiting
Authors: Xia Yan , Chen Maowen , Li Suwan , Li Man , Li Xianying , Yi Tao , Zhang Dengqing
Published: August 2022

The artificial light-harvesting system (MPy1–ESY–SR101) with two-step sequential energy transfer constructed in this work serves as a privileged platform for multilevel data encryption and anticounterfeiting.
A novel acid-controlled second-order nonlinear optical switch based on dimethyldihydropyrene/cyclophanediene photoswitch
Authors: Yao Yao , Xu Hong-Liang , Su Zhong-Min
Published: August 2022

The structure of the DHP–CPD core was modified chemically by different acceptor and donor groups, showing interesting NLO switch characteristics upon protonation.
On characterisations of the input to state stability properties for conformable fractional order bilinear systems
Authors: Nozari Hasan Abbasi , Rostami Seyed Jalil Sadati , Castaldi Paolo
Published: August 2022

This paper proposes for the first time the theoretical requirements that a fractional‐order bilinear system with conformable derivative has to fulfil in order to satisfy different input‐to‐state stability (ISS) properties. Variants of ISS, namely ISS itself, integral ISS, exponential integral ISS, small‐gain ISS, and strong integral ISS for the general class of conformable fractional‐order bilinear systems are investigated providing a set of necessary and sufficient conditions for their existence and then compared. Finally, the correctness of the obtained theoretical results is verified by numerical example.
A bi‐level transactive control model for integrating decision‐making and DLMP‐pricing in distribution networks
Authors: Li Biao , Wan Can , Luo Fengji , Yu Peng , Sun Mingyang
Published: August 2022

The market‐driven demand side management of distribution networks suffers from the challenge of operational security issues. This paper proposes a distribution locational marginal price (DLMP) based bi‐level transactive control model for distribution networks to manage demand side resources of nodal agents, ensuring both the network security and the agents' optimal decision. The proposed model consists of a DLMP‐pricing model at the upper level and DLMP‐based demand response (D‐DR) models at the lower level, integrating the DLMP‐pricing of the distribution network and the decision‐making of agents. The DLMP‐pricing model is constructed as the dual form of a linearized optimal power flow problem to determine DLMP related to the decision of all agents. The D‐DR model enables each nodal agent to minimize its own expenditure under the DLMP, which is established as a linear programming problem. The bi‐level model is converted into single‐level programming through replacing the D‐DR models by Karush‐Kuhn‐Tucker conditions, in which the bi‐linear items of the complementary slackness are further linearized by introducing integer variables. Consequently, the intractable bi‐level transactive control model is equivalently reconstructed as a single‐level mixed‐integer linear programming problem that can be conveniently solved. Comprehensive numerical studies validate the effectiveness of the proposed model.
Heuristic DRP‐DG optimization strategy adopted for maximizing total social welfare in the real time Indian utility network
Authors: Sharmila Punnianathan , Mahadevan Senthilkumaran , Baskaran Jeevarathinam , Nayanatara Chandrasekaran
Published: August 2022

The energy sector is subjected to an increase in power demand year after year. This increase in energy demand will continue due to the need for energy for modern societies. The service providers should face this situation smartly using renewable energy sources to avoid the intermittent nature of these sources and the fluctuations in the demand. Demand response programs (DRP) can play a vital role in increasing the correlation between the loads and the available generation from renewable energy sources (RES). Modern power systems recommend the use of distributed generation (DG) sources to reduce the transmission losses, contingency, and cost of energy and to increase the system reliability, efficiency, and power system loadability. Optimal DR use in the DG can further improve its performance which is the main focus of this paper. Here, a novel DRP‐DG strategy is introduced to size and allocate the DG units for minimum congestion in IEEE 33‐bus benchmark power system and real Indian power system having 17 buses. The active involvement of the consumers in the DRP facilitates the ultimate objective of maximized total social welfare (TSW) with minimized generation costs. To justify the above multi‐objective optimization, two stages of heuristic optimization are introduced in which the rules are fired in the primary stage for determining the optimal size of DG. Implementation of DRP for achieving comprehensive objective function is vindicated in the secondary stage. A real‐time Indian utility network is considered and a trade‐off output is realized using heuristic fuzzy logic (FL) and genetic algorithm (GA). The results obtained from using the proposed strategy proved its superiority in achieving substantial cost reduction and maximum TSW compared to other soft computing techniques.
Morphological changes in sheep blood when using the associated vaccine against salmonellosis and pasteurellosis
Authors: Makhmudov K.B. , Sattori I.
Published: August 2022

The article presents the results of studies on the use of an associated vaccine against salmonellosis and pasteurellosis. It was found that the number of erythrocytes and leukocytes in the blood of vaccinated animals increases, as well as the levels of hemoglobin, total protein and its fraction, which indicate a positive effect of the associated vaccine on hematological parameters and the content of total protein in the blood of animals.
The application of the Photoditazine photosensitizer for the sanation of industrial poultry products
Authors: Shlenskiy Vadim , Pashnik Tatiana , Pigina Svetlana
Published: August 2022

The scientific work analyzes the effectiveness of the Photoditazine photosensitizer for the sanation of poultry products, namely broiler chicken carcasses and chicken eggs to reduce bacterial contamination of the final product. The quality of the products processed with the Photoditazine photosensitizer was assessed from the point of view of veterinary and sanitary expertise and microbiology. Specific and quantitative identification of microflora of chicken carcasses and chicken eggs was carried out during treatment with Photoditazine photosensitizer. Based on the results obtained, it can be concluded about the effectiveness of the Photoditazine photosensitizer in industrial poultry farming for the sanation and improvement of food safety of final products.
Zoning of rice growing territory of Krasnodar region by the set of features of Pyricularia oryzae Cav. isolation
Authors: Nartymov Dmitriy , Dubina Elena , Kharitonov Evgeniy , Garkusha Sergey
Published: August 2022

The geographical location and relief of the Krasnodar Territory determines a wide variety of agro-climatic and agro-technological conditions for the production of crops. On the territory of the Krasnodar Territory there is the largest part of agricultural land intended for the production of rice crops in Russia. Annual infection of rice plants with pathogenic Piricularia Orizae Cav. due to a wide range of strain diversity and indicates a significant dependence of the population genotype on the territorial distribution area. Therefore, the identification of zones that determine the conditions for the spread of blast within the population plays an important role in studying the dynamics of pathogen development in the territory of rice cultivation. The results of the research work showed that the Krasnodar rice growing area has a uniform landscape without sharp changes in the relief profile. The location of adjacent geographical objects affects the agro-climatic conditions of the southern part of the territory, which indicates the likelihood of isolation of the population of rice blast strains in the southern part of the rice growing area. An analysis of the agricultural zoning of the Krasnodar Territory showed the isolation of the southern part of the rice-growing territory according to the characteristics of the soil cover and the isolation of the conditions of agrotechnological measures. Features of the water regime of the irrigation systems of the Krasnodar Territory indicate the differentiation of the factors of infection and the spread of the pathogen on the basis of the isolation of irrigation flows. The territory has a clear division along the channels of the Kuban and Protoka rivers.