bluuebunny/crossref_metadata_2025 huggingface dataset:
AI-Driven Education, Careers, and Entrepreneurship for a Transformed Tomorrow
Authors: Burton Sharon L , O'Neal Derrick
Published: November 2024

In this in-depth exploratory case study of artificial intelligence (AI), the researchers applied a scaled, reactive, and parallel approach relating to education, employment, and entrepreneurship, wherein the data from the previous case study was used to inform the next of three case studies. Dissimilar to what was supposed from extant literature, the results revealed that AI may support learning without escalating biases or inequities. Increased and continued learning occurred within two weeks of the first pilot.The findings contribute to the resourcing literature by unveiling the capability to apply AI-driven data to boost an increase in behavioral learning, whether classical, operant, or observational. Specifically, the data shows that underperforming students, those lagging on standardized tests, and those of lower income levels can increase their learning when offered individualized and adaptive learning tailored to distinct needs,  preferences, and abilities. The change is due to increased purposive attention that is AI-driven and maintains learners' interests through an avatar. This study shows how AI progress, particularly scaled, reactive, and parallel AI, can lead to new tools and services for advancements that impact performance support, employment trends, corporate learning, and professional development. Also, the study shows that AI-driven education can improve job prospects and career growth, benefiting learners, academics, and practitioners. This exploratory research results inform widespread AI implementation, fostering educational and career synergies.
Metaverse Applications in Education 4.0: A Decade of Systematic Literature Review
Authors: Ghoulam Khalid , Bouikhalene Belaid
Published: November 2024

The advent of Education 4.0, which aligns with the fourth industrial revolution, has been significantly influenced by advancements in digital technologies. Central to this evolution is the metaverse, a virtual shared space that merges augmented reality, virtual reality, and physical reality. This paper delves into the metaverse's applications within Education 4.0, highlighting its potential to revolutionize learning experiences, enhance collaboration, and improve access to quality education. By reviewing current literature and case studies, we identify the primary benefits, such as increased engagement, personalized learning, and broader accessibility. Additionally, we address the challenges associated with metaverse integration, including technical limitations, privacy concerns, and the need for new pedagogical approaches. Through a mixed-methods research approach, combining qualitative and quantitative data along with expert interviews, this paper provides a comprehensive overview of the metaverse's role in future education. The findings suggest that while significant hurdles remain, the metaverse offers a promising avenue for transforming educational practices to meet the demands of the digital age, ultimately fostering more dynamic, inclusive, and effective learning environments. Future research should focus on evaluating long-term impacts and developing standards for metaverse applications in education.
Santa María Academy: Shaping the Heroes of Today with Tomorrow's Technology
Authors: Del Valle Mejías María Elena
Published: November 2024

Santa María Academy has successfully integrated advanced technology into its educational framework to enhance the learning experience of its students, preparing them for future careers in law enforcement and the military. The academy's innovative approach includes personalized coaching, interactive resources, and smart tools that cater to individual student needs. By leveraging artificial intelligence and real-time performance monitoring, Santa María Academy has significantly improved student outcomes, motivation, and engagement. This case study explores the key elements of their success, including the implementation of personalized learning plans, interactive podcasts, a smart syllabus, and a real-time performance dashboard. The academy's model serves as a benchmark for educational institutions aiming to merge traditional values with cutting-edge technology to produce well-rounded and highly skilled graduates.
Retour sur l’archéologie mortuaire d’époque médiévale dans le sud-ouest du Nigéria
Authors: Chapelain de Seréville-Niel Cécile , Chouin Gérard , Ogunfolakan Adisa
Published: November 2024

Dans quelle mesure les os humains identifiés en fouilles depuis les années 1960 dans deux centres urbains majeurs du Nigéria médiéval pourraient-ils témoigner – ou pas – du passage, dans la seconde moitié du xive siècle, de la pandémie de peste ? Notre réflexion s’appuie sur l’analyse des ossements d’individus retrouvés dans une fosse commune à Benin City en 1962-1963, des restes très partiels d’un enfant mis au jour sur le site d’Oduduwa College II, à Ile-Ife en 2019, et sur des descriptions de restes humains découverts lors de différents projets archéologiques dans cette cité centrale du monde yoruba. La position stratigraphique des squelettes, la disposition des corps, les marques observées sur certains os sont autant d’éléments qu’il nous faut prendre en compte pour nourrir notre réflexion sur la peste et plus largement sur les pratiques mortuaires en Afrique tropicale avant l’ouverture du commerce atlantique, et leurs conséquences sur les dépôts archéologiques.
Simulation of a Silicon Solar Cell Using Triple-Layer Anti-Reflection Coatings (ARC)
Authors: Mohd Jamaluddin Nur Irdina Iwani , Yusoff Mohd Zaki Mohd , Malek Mohd Firdaus , Artes Jr. Rosalio G. , S. Sala Jamaluddin
Published: November 2024

Considering solar energy is being used more and more frequently in recent years, numerous studies have been conducted in order to improve the performance of the solar cell. The application of anti-reflective coating (ARC) in the solar cell is one of the most effective techniques. It has been said that although single and double ARC layers are adequate, applying triple ARC layers would render them significantly more effective across a broad spectrum. Henceforth, in this study, different materials were recently designed to produce triple layers of ARC, which are SiO2/Si3N4/TiO2, SiO2/ZnO/TiO2, ZnO/Si3N4/TiO2, SiO2/Si3N4/ZnS, and SiO2/ZnO/ZnS, which are then applied in silicon solar cells using PC1D simulation software. The outcomes of the simulation included the analysis of the I-V curve, efficiency (ŋ), and reflection, in addition to the results for short circuit current (Isc), maximum power output (Pmax), open circuit voltage (Voc), and fill factor (FF), which have been compared to numerous other theoretical findings from other investigations and research projects. By that, the simulation revealed that SiO2/ZnO/TiO2 is the most suitable triple-layer ARC to be applied to a silicon solar cell, which exhibits the highest efficiency of 22.63% with an Isc of 3.967A, Pmax of 2.489W, a Voc of 0.7389V, and a fill factor of 84.91 at a wavelength of 400 nm.
Study of Mechanical Properties Using Carbonized Rice Husk and Eggshell to Prepare Sustainable Concrete and its Viability in Civil Construction
Authors: dos Santos Danielle Ferreira , de Meirelles Philippe Bachmeyer , Machado Zaqueu Rodrigues
Published: November 2024

Sustainability has become an increasingly present concern in the construction industry, which has led to a search for more ecological and sustainable alternatives in the production of construction materials. In this context, research references have shown promising results in the use of carbonized rice husk and eggshell. The use of rice husk as a partial substitute for cement in concrete has proven to be effective in reducing environmental impact, since this residue has pozzolanic characteristics, providing greater resistance to the concrete. Eggshell, in turn, has been used as an additive in the production of mortars, providing improvements in the mechanical and thermal properties of these materials. These sustainable solutions in civil construction are aligned with the ESG agenda of companies, which are increasingly seeking minimize the environmental impact of its activities. The study verified through axial compression resistance tests that the composites prepared with 1.5 % (w/w) had superior compressive strength by around 20% compared to the composites prepared with 2 % (w/w). In other words, with a lower concentration it achieved a satisfactory reinforcement effect, better preserving the structure. From the analysis of the diametral compression resistance results, the concentration of 1.5% (w/w) showed a specific reinforcing effect, both with the use of crushed eggshells and with the use of carbonized rice husks dispersed in concrete. The concentration of 1.5% (w/w) showed a specific reinforcing effect, both with the use of crushed eggshells and with the use of carbonized rice husks dispersed in concrete. The lowest content of 1% (w/w) was not enough to reinforce the material, presenting the lowest yield strength values of 2.98 and 3.54 MPa for egg and rice, respectively. The values for 1.5% (w/w) reached values of 4.22 and 4.68 MPa, for egg and rice. Around 20% of the compounds prepared with the highest filler levels, both with crushed eggshell and carbonized rice husk.
Stabilizer Effects on the Gelation of Modified Recycled PET for 3D Printing Filament Application
Authors: Parneam Nismar , Ayutthaya Siriorn Isarankura Na , Sukhawipat Nathapong , Komonhirun Seekharin
Published: November 2024

This research identification gel types of the modified-recycled poly (ethylene terephthalate) (modified-rPET) filament, with and without the addition of heat stabilizer Pentaerythritol tetrakis(3-(3,5-di-tert-butyl-4-hydroxyphenyl) propionate (Irganox®1010). This research also identifies the gel types and studies thermal behavior of the modified-rPET filaments above, by using a hot-stage microscopy, and a differential scanning calorimetry, respectively. rPET flakes were dried to deplete the moisture. Then, they were mixed with additives and heat stabilizer (Irganox®1010) at 0 and 0.5 pph, Then, they were extruded to be compound using twin screw extruder. The compounds were extruded into filament by using filament extruder. The two temperature profiles were used. The first and the second temperature profiles from the feed zone to the die zone were 275-275-275 oC and 290-290-290 oC, respectively. The extrudate of modified-rPET with and without heat stabilizer, were investigated the type of gel and the thermal behavior of the modified-rPET filament. From this preliminary experiment, it was found that the “unmelt-gel” defect was found from the modified-rPET filament, without the addition of Irganox®1010. On the other hand, the “crosslinked gel” defect was found from the modified-rPET filament, with the addition of Irganox®1010. Therefore, the addition of heat stabilizer (Irganox®1010) may cause the “crosslinked gel” significantly. Our future work, we will investigate the effect of another stabilizer and chain extenders on the gelation behavior, to complete this clarification systematically.
Properties of Steel Fiber Reinforced Desert Sand Concrete
Authors: Yu Rui , Huang Yong , Sun Jian , Liu Yu Bin , Li Si Ning , Luo Si Yu , Liu Zeng Shui
Published: November 2024

To study the effect of steel fibers on the mechanical properties of desert sand concrete (DSC), three lengths (12 mm, 16 mm, and 20 mm) of steel fibers and five volumetric admixtures (0.4%, 0.8%, 1.2%, and 1.6%) of steel fibers were selected to make 13 groups of concrete specimens (78 cubic specimens and 39 prismatic specimens). Compressive test, splitting test and flexural test were carried out on the specimens of DSC after curing for 28 days. According to the test results, the influence law of each parameter on the mechanical properties of DSC was analyzed, and the working principle of steel fibers to improve the mechanical properties of DSC was described by combining macroscopic and microscopic methods. The results showed that the addition of steel fibers can effectively improve the damage pattern of DSC, and all the mechanical properties of DSC are improved; 12 mm steel fibers were relatively effective in enhancing the compressive strength of DSC and 20 mm steel fibers were relatively effective in enhancing the splitting and flexural strength of DSC; Both macroscopic and microscopic results showed that the addition of appropriate amount of steel fibers can effectively fill the internal pores of DSC. The results can provide theoretical basis and technical support for the engineering application of steel fiber reinforced DSC.
Evaluation of stevia leaf (Stevia rebaudiana Bertoni) powder as sugar-substitute in cashew nut fortified cookies
Authors: Dilrukshi H. M. W. , Ulpathakumbura B. S. K. , Gunarathna K. M. R. U. , Iqbal M. C. M. , Lai O. M. , Marikkar J. M. N.
Published: November 2024

Stevia rebaudiana is an herbal supplement used as a substitute for sugar in food processing. Considering the potentials of stevia as a zero-calorie-natural sweetener, this study aimed to assess the antioxidant and anti-hyperglycemic properties of stevia (Stevia rebaudiana Bertoni) leaf powder (SLP) to find its suitability to formulate low-calorie foods.  Extracts of SLP obtained with hexane, ethyl acetate, and methanol were evaluated for DPPH, ABTS+, FRAP and enzyme inhibitory assays. Adopting a standard recipe, five different cookie types were prepared by incorporating varying proportions of SLP and evaluated by a 30 semi-trained panel. The nutritional composition and shelf-life stability were also evaluated. SLP had moisture (8.0 %), ash (13.5 %), crude protein (12.4 %), crude fat (6.9 %), crude fiber (18.3 %), and carbohydrate (40.9 %). Sensory results showed that the cookie formulated with the lowest amount of SLP (T1= 2.0g) had the highest overall acceptability with the highest preference for appearance and smell. The cookie type formulated with the highest amount of SLP (T4= 8.0g) had the highest crude protein (13.50%), crude fiber (21.76%), and lowest carbohydrate contents (40.88%). The keeping quality of the cookies remained acceptable within the storage period. These results suggest that acceptable quality cashew nut fortified cookies could be prepared by replacing sucrose with stevia leaf powder
The Effect of Border Crops and Physical Barriers on Incidence of Chilli Leaf Curl Complex and Associated Insect Populations
Authors: Sirisena U. G. A. I. , Devasinghe D. A. U. D. , Warnasooriya W. M. R. S. K. , Wickramasinghe W. M. D. M. , Wijesinghe W. M. J. B. , Mandanayake M. A. R. A.
Published: November 2024

Chilli Leaf Curl (CLC) possesses a significant biotic threat leading to substantial yield losses in chilli cultivation. Various agents such as thrips, aphids, mites and the viruses transmitted by whiteflies have been identified as contributors to CLC. In order to mitigate this issue, three types of physical barriers were used: an insect-proof net (1 m high) surrounded by three rows of maize crops, an insect-proof net (1 m high) alone, and three rows of maize crops. A control was maintained without a physical barrier. The experiment was laid out as randomized complete block design with three replicates. Identification of pests and diseases, CLC disease incidence and yield attributes were assessed. Results revealed that the treatment with an insect-proof net combined with a maize border exhibited the lowest disease incidence (2±0.45, p=0.01) compared to chilli plants with a maize border only. The whitefly population varied across the treatments (p=0.03) and with the age of the crop (p<0.0001). Among the treatments, the control and insect-proof net exhibited a significantly lower population of whiteflies. Thrips did not show a significant response to the treatments (p=0.54) indicating that the presence of physical barriers had no notable effect on thrips counts. Additionally, there was no significant difference in the number of pods per plant (p=0.74) and yield per plant across the treatments (p=0.54). In conclusion, the use of insect-proof net with a maize border surrounding the chilli cultivation would help to develop integrated pest management strategies to reduce chilli leaf curl incidence as well as whitefly population.
Clinical profiles and shortterm outcomes of women with peripartum and dilated cardiomyopathies
Authors: Muhammad Babalawan , Ishaq Naser A. , Karaye Kamilu M.
Published: November 2024

Background: We aimed to compare the clinical and sociodemographic characteristics, rate of left ventricular reverse remodeling (LVRR), heart failure hospitalization and allcause mortality of women with peripartum and dilated cardiomyopathies (PPCM and DCM respectively) in Nigeria. Methods: This was a prospective longitudinal study and a total of 130 patients (65 for each group) were recruited consecutively and followed up for 6 months. Results: PPCM patients were younger, but the DCM patients had higher frequency of atrial fibrillation and complete left bundle branch block, higher mean left atrial and LV dimensions, higher LV filling pressures, and worse renal dysfunction, respectively, at baseline. At the end of the 6month followup, 15 female DCM vs 21 PPCM patients (p=0.684) had achieved LVRR, 13 DCM vs 11 PPCM patients (p=0.098) were hospitalized for heart failure, and 10 DCM vs 5 PPCM patients (p=0.098) had died. The odds for achieving LVRR was independently increased by systolic blood pressure (SBP) >100 mmHg and tricuspid annular plane systolic excursion >16 mm at baseline in PPCM patients, and by use of angiotensin converting enzyme inhibitors at baseline in female DCM patients. The odds for mortality were increased by tachycardia and pericardial effusion and reduced by the use of loop diuretics at baseline in DCM patients, and SBP <90 mmHg at baseline increased it by 9fold in PPCM patients. Conclusions: Our results suggest that women with DCM and PPCM differ significantly in their demographic and clinical characteristics, and predictors of clinical outcomes.
Utopia: un’ideale riflessione sull’infermieristica
Authors: Scelsi Silvia
Published: November 2024

Il concetto di utopia,1 inteso come una visione ideale e perfetta della società (dal nome del paese che non esiste ideato da Tommaso Moro), è spesso evocato quando si riflette sul futuro delle professioni, soprattutto in ambiti come quello sanitario. L’infermieristica è una professione storicamente legata alla cura e al benessere delle persone e si presta particolarmente a queste riflessioni.
In un mondo dove la sofferenza e la malattia sono presenti, dove la cronicità è sempre più una condizione diffusa, l’infermiere rappresenta una figura fondamentale, soprattutto in un sistema che vorrebbe, almeno nelle norme, cambiare il proprio paradigma sulla salute, iniziando dall’implementazione del benessere, e dalla promozione della salute. Ma cosa significherebbe raggiungere questa perfezione nel contesto di un sistema sanitario in continua evoluzione? Sarebbe davvero immaginabile? [...]
Necrotizing Fasciitis in a Lactating Breast: A Case Report and Literature Review
Authors: Janjua Nusrat Batool , Mohammedelfateh Adam , Vanapalli Manju Rao , Mc Cabe Mark , Bulfin Claire , Stratton John
Published: November 2024

Abstract

Introduction:

Necrotizing fasciitis (NF) is a serious, rapidly progressive disease with significant maternal morbidity and mortality. This case report highlights the rare occurrence of NF in a lactating breast.

Patient concerns:

A 3-week postnatal young patient exclusively breastfeeding developed left breast engorgement and pain and received two courses of antibiotics for left mastitis. At 6 weeks postnatal, she presented to the hospital with a left breast abscess and fever.

Diagnosis:

Inflammatory markers were raised. Ultrasound confirmed the presence of a breast abscess.

Intervention:

The patient was started on antibiotics, and ultrasound-guided aspiration was performed. However, the skin turned black with a rapidly spreading infection; subsequently, she had a debridement of necrotic breast tissue and a biopsy in the theater. Histology confirmed a diagnosis of NF.

Outcome:

A wound dressing with negative pressure wound therapy was applied. The patient was prescribed Cabergoline 0.25 mg every 12 hours for 2 days to stop milk production. She responded well to an autologous skin graft by the breast team and was discharged.

Conclusion:

The report emphasizes the importance of considering NF as a potential diagnosis in cases of infection in a lactating breast unresponsive to conventional treatment. Early diagnosis and prompt treatment with antibiotics, surgical debridement, and multidisciplinary care are prudent to prevent adverse sequelae, such as sepsis, partial/total mastectomy, and psychological distress. A biopsy is mandatory to exclude coexistent malignancy.
Laboratory analysis of 124 chronic lymphocytic leukemia cases: Single center study
Authors: Mahdi Shams Salah , Al-Sarai Nuha Abd Ali
Published: November 2024

BACKGROUND:

Chronic lymphocytic leukemia (CLL) is a disease characterized by an uncontrolled proliferation of malfunctioning mature B-lymphocytes. It represents a variable range of clinical presentation and prognoses. Understanding the demographic and cellular characteristics of CLL patients can aid in better disease management and treatment outcomes.

OBJECTIVES:

To identifying hematological parameters and patterns and potential markers that could assist in better diagnosis and of CLL in the local population.

PATIENTS, MATERIALS AND METHODS:

A retrospective analysis of 124 cases of newly diagnosed CLL was conducted. Data were collected from reports over 2 years (April 2022-April2024), including demographics, Hb levels, WBC counts, platelet counts and expression of CD markers (5, 19, 20, 23, 200, FMC7, LAIR1 and others) using flow cytometry on peripheral blood specimens. Based on FC findings, patients were categorized into two groups for better assessment; definite diagnosis CLL and possible diagnosis CLL; then further subdivided into poor prognosis CLL and good prognosis CLL.

RESULTS:

Male patients represented 59.5% of cases and females were 40.5% with a median age of 61 years at diagnosis. The mean Hb level was 109 ± 2 g/L, the mean WBC count was 58.0 ± 25.0 × 109/L, and the mean platelet count was 190 ± 40 × 109/L. CD5 was positive in 97.6% of cases, with CD23 in 96%.

CONCLUSION:

This study provides an overview of the demographic and cellular marker characteristics of CLL patients in FC unit. The findings underscore the heterogeneity of CLL immunophenotype and the importance of detailed characterization in improving patient management protocols; however, further research is warranted to correlate these findings with other parameters of disease burden and prognosis to optimize the therapeutic approaches for CLL patients.
Does Real-time Feedback Guide Devices Improve the Quality of Chest Compressions in the Bystander (Naves) Provider?
Authors: AlSayed Thamir , Haliq Samer Al , Katbi Faisal , Alghamdi Mohannad , Almulhim Mohammed
Published: November 2024

Introduction:

Cardiopulmonary resuscitation (CPR) is an important lifesaving technique that must taught to everyone. As most cardiac arrests occur outside of the hospital, training the general population in the recognition of cardiac arrest and performing high-quality CPR is vital. Thus, this study aimed to compare the chest compression quality data (rate, depth, and fraction) with and without the use of feedback devices during CPR.

Methods:

A crossover observational study was carried out at a tertiary hospital in September 2021. Five hundred and seventeen 1st-year university students were recruited, and the response rate was 90% (465). A feedback device was used to collect data. The data were numerically coded and statistical software (SPSS 21) was used to perform descriptive and inferential statistical analysis, including a paired t-test.

Results:

The mean compression rate with feedback was statistically significantly lower after performing one cycle of CPR (mean difference: −5.610; 95% confidence interval [CI]= −7.987–−3.233; P < 0.001), the difference between mean compression depth with and without feedback was not statistically significant (mean difference: = −0.006; 95% CI = −0.190–0.177; P = 0.944), and the mean compression target (%) with feedback was statistically significantly higher (mean difference: −15.951; 95% CI = −17.894–−14.009; P < 0.001).

Conclusions:

We found that the use of feedback devices during layperson-simulated CPR scenarios significantly improved the quality of chest compression in terms of depth and rate and resulted in more guidelines adherence. Moreover, national programs for CPR education should be implemented.
Successful Endoscopic Management of Complete Tracheal Occlusion in a Child
Authors: Balaji Bhavya , Dcunha Aureen Ruby , Rai B. Sandeep , Giridhar B. H. , Rao Swathi Sunil
Published: November 2024

ABSTRACT

Prolonged mechanical ventilation following cardiopulmonary and neurological events oftentimes necessitates a tracheostomy and tracheal granulation is one of its most common late complications. The literature recommends that large granulation be managed through surgical excision or endoluminal techniques. A 6-year-old boy presented with high-grade tracheal stenosis secondary to endotracheal cuff-related injury and prolonged tracheostomy. We present an unconventional yet successful method of management that included multiple sittings of endoscopic rigid bronchoscopic dilation and endoluminal cryotherapy.
Ovarian Masses in Children: Surgical Experience and Outcomes
Authors: Kapoor Rohit , Mandelia Ankur , Kumar Basant , Upadhyaya Vijai Datta , Verma Anju , Kanneganti Pujana , Kumar Tarun , Agarwal Nishant , Goel Rahul , Prajapati Pooja
Published: November 2024

ABSTRACT

Aims:

This study aims to review our experience of treating ovarian masses in children with an emphasis on clinical presentation, diagnosis, treatment, and outcome.

Methods:

We retrospectively reviewed the electronic medical records of all patients below 18 years of age who underwent surgical treatment for ovarian masses at our institute between 2009 and 2023. Study variables included demography, clinical presentation, physical findings, tumor markers, radiologic features, operative details, histopathology, follow-up status, and overall survival.

Results:

During the study period, 30 patients with a mean age of 10.07 years (range: 15 days–18 years) underwent surgical treatment for ovarian masses. Nonneoplastic ovarian masses were seen in 5 (16.7%) patients, whereas 25 (83.3%) patients had benign (10 [33.3%], borderline 3 [10%], or malignant 12 [40%]) ovarian neoplasms. The most common clinical presentation in the benign group was abdominal pain (n = 6), whereas painless abdominal mass (n = 6) was the predominant complaint in children with malignant tumors. A functional ovarian mass presenting with precocious puberty or virilization was seen in 5 (16.7%) patients. On imaging, nonneoplastic and benign lesions had a mean size of 4.33 (range: 3.1–6) cm and 12.63 (range: 2.8–28) cm, respectively, whereas borderline and malignant masses had a mean tumor size of 22.5 (range: 6.5–32) cm and 12.55 (range: 3.5–18.7) cm, respectively (P < 0.05). The cystic component was identified in all nonneoplastic and benign tumors, whereas the solid component was present in all borderline and malignant lesions (P < 0.05). Tumor markers such as serum alpha-fetoprotein and beta-human chorionic gonadotropin were raised in 8 (66.67%) of malignant tumors, whereas markers were normal in all benign lesions and borderline malignant lesions and 4 (33.33%) of malignant tumors. Lactate dehydrogenase (LDH) was also raised in all malignant masses (n = 12), whereas it was normal in all benign and borderline malignant masses (n = 18). In 6 (20%) patients with nonneoplastic and benign masses with maximum tumor size <6 cm, the laparoscopic approach was adopted, whereas open surgery was preferred in the rest of the patients. At a mean follow-up of 53.5 (range: 4–117) months, all patients are alive and disease free.

Conclusions:

Preoperative imaging characteristics (tumor size and solid component) and raised tumor markers may help us to differentiate between benign and malignant ovarian pathologies. The overall prognosis of pediatric ovarian tumors seems to be favorable.
Improving Fault Classification Accuracy Using Wavelet Transform and Random Forest with STATCOM Integration
Authors: Umathe Shradha , Daigavane Prema , Daigavane Manoj
Published: November 2024

INTRODUCTION: Fault detection in transmission lines is critical for keeping the grid stable and reliable. This research offers a new methodology, the Wavelet Transform-Enhanced Random Forest Fault Classification System with STATCOM Integration (WERFCS-SI), to solve the shortcomings of existing fault detection approaches. OBJECTIVES: The integration of STATCOM-compensated transmission lines improves fault detection capabilities. The Wavelet Transform finds faults by analysing approximation and detail coefficients, allowing for multiresolution analysis and exact fault localisation. METHODS: Feature selection approaches, such as information gain, are used to discover and keep relevant features, increasing classification accuracy. RESULTS: Due to its ability to process complex, high-dimensional data and identify minute feature connections, Random Forest (RF) is utilised for classification tasks. The proposed approach improves RF model performance while maintaining precision. CONCLUSION: The integrated technique simplifies fault categorisation, increasing accuracy and efficiency by detecting problems in the transmission line system.
UNA INVESTIGACIÓN EN DIDÁCTICA DE LA HISTORIA EN LA NORPATAGONIA ARGENTINA
Authors: Graciela Funes Alicia , Ángel Jara Miguel
Published: November 2024

Como investigadores en Didáctica de la Historia, en una universidad pública de la nord Patagonia Argentina, nos interesa compartir algunas reflexiones en torno a la constitución del campo de investigación a partir de nuestras experiencias como formadores e investigadores. Hemos desarrollado investigaciones educativas de carácter cuanti-cualitativo cuya finalidad ha sido producir conocimientos en torno a la educación histórica y a la formación docente en ciencias sociales y en Historia, al mismo tiempo que reflexionar sobre el oficio del investigador.La formación docente concebida como trayectoria, como proceso continuo y permanente es imprescindible para llevar a la prácticaun proyecto pedagógico. Focalizando en diversos momentos de esa trayectoria hemos estudiado: las prácticas docentes en la formación inicial de maestros/as y de profesores/as en Historia también, investigamos la formación docente en servicio atendiendo a la diversidad de experiencias formativas y laborales.
¿ENSEÑAMOS LO CORRECTO? EL CONCEPTO DE FRONTERA BINACIONAL ENTRE ARGENTINA Y CHILE Y LA CONSTRUCCIÓN DE UNA IMAGEN NEGATIVA DEL “OTRO” EN LOS TEXTOS ESCOLARES DEL BICENTENARIO DE AMBOS PAÍSES
Authors: Vergara Poblete Esteban
Published: November 2024

Esta investigación tuvo por objeto de estudio la imagen que existe en Chile de Argentina y viceversa, a partir del concepto defrontera presente en algunos de los textos escolares empleados por estudiantes argentinos y chilenos durante el año 2010. Para ello se realizó un análisis discursivo de los textos en cuestión para identificar la forma en que se expone en ambos Estados el proceso de construcción de la frontera chileno-argentina, así como un análisis comparativo dela cartografía que se presenta en los textos escolares respecto a ello. Los principales resultados obtenidos demuestran la persistencia en los textos escolares argentinos y chilenos de un discurso nacionalista que pretende mostrar al “otro” como agresor y sustractor de territorios, lo que lleva a replantearse el papel del docente en la enseñanza de los temas controversiales, su compromiso y el tipo de formación ciudadana que se intenta desarrollar en ambos países.
ENTORNOS DE APRENDIZAJE DIGITAL PARA LA ENSEÑANZA DE LA HISTORIA RECIENTE EN ESPAÑA Y CHILE. PRESENTACIÓN DE UN PROYECTO DE INTERVENCIÓN EN SECUNDARIA.
Authors: SÁNCHEZ AGUSTÍ MARÍA , GONZÁLEZ GALLEGO ISIDORO , MIGUEL REVILLA DIEGO , MARTÍNEZ RODRÍGUEZ ROSENDO
Published: November 2024

Bajo el término de historia reciente se engloban una se- rie de procesos históricos que forman parte de las vivencias de una o varias generaciones de los ciudadanos actuales. Su proximidad tempo- ral al momento actual y el auge de las tecnologías de la información y la comunicación de las últimas décadas han propiciado la existencia de abundantes fuentes informativas para el estudio de estos procesos.
Desde la perspectiva educativa, esta cercanía y su caracter vivencial confieren a esta parte del pasado un alto potencial didáctico, dado que permite a los profesores utilizar un amplio abanico de fuentes históricas presentes en las TICs y vincular los contenidos con el ámbito familiar de los adolescentes, produciendo aprendizajes más motivados y comprensivos.
Por tanto, es necesario, y ello constituye el objetivo principal del proyecto que aquí presentamos, proponer la inclusión curricular de modelos didácticos con fuerte componente tecnológico en relación con la historia reciente, e investigar el impacto producido en los apren- dizajes de los estudiantes de secundaria en relación con el desarrollo del pensamiento histórico.

Se espera que la elaboración y aplicación de propuestas docentes in- novadoras para enseñar estos procesos permita valorizar estos con- tenidos, otorgándoles el importante papel que deben tener, no solo en la construcción del conocimiento histórico de los estudiantes, sino también en su formación ciudadana. Dichas propuestas estarán so- portadas, fundamentalmente, en material educativo tecnológico, lo que contribuirá a crear entornos de aprendizaje más activos y eficaces, erradicando metodologías exclusivamente transmisivas, fuertemente enraizadas en las clase de Historia.
PRESENTACIÓN
Authors: VÁSQUEZ LEYTON GABRIELA
Published: November 2024

El siguiente número corresponde a una convocatoria especial que tiene por finalidad presentar algunos de los trabajosexpuestos en el VI Simposio Internacional de Didáctica de las Ciencias Sociales en el Ámbito Iberoamericano, desarrollado en la ciudad de Yucatán (Mérida, México) en octubre del 2015.
LOS CONTENIDOS SOBRE HISTORIA EN LA FORMACIÓN DE PROFESORES EN MÉXICO: DEL ESTUDIO DE LA REALIDAD SOCIOPOLÍTICA A LOS CONCEPTOS DE PRIMER Y SEGUNDO ORDEN
Authors: PLAZOLA DÍAZ MARÍA DEL REFUGIO , LIMA MUÑIZ LAURA H.
Published: November 2024

En este artículo presentamos algunas reflexiones sobre los cambios y/o continuidades de las propuestas curriculares para la formación de docentes en México, que se forman en las escuelas normales, sobre los contenidos de Historia de acuerdo a los tres últimos Planes de Estudio: 1984, 1997 y 2012. En el análisis de estos Planes de Estudio, analizamos algunos puntos centrales como: los enfoques pedagógicos, las temáticas que se privilegian para la formación de los docentes en la línea social hasta llegar a la propuesta específica sobre los contenidos de Historia y el sentido formativo del Plan 2012 de la Licenciatura en Educación Primaria.
ENSEÑANZA DE LA TEORÍA DE LA HISTORIA EN LA ESCUELA: DESAFÍOS PARA EL DESARROLLO DEL PENSAMIENTO HIST´ÓRICO
Authors: Guajardo Olguín Valentina
Published: November 2024

El paradigma actual que guía la enseñanza y el aprendizaje de la historia sitúa al centro del proceso educativo al desarrollo progresivo de habilidades vinculadas al pensamiento histórico...
REFERENCIAS
Authors: Oyanedel Bernal Carmen
Published: November 2024

"Busca siempre un quehacer; cuando lo tengas no pienses en otra cosa que hacerlo bien" Tales de Mitelo
OTRAS REVISTAS DE DIDÁCTICA DE LA HISTORIA
Authors: Andamio Equipo
Published: November 2024

OTRAS REVISTAS DE DIDÁCTICA DE LA HISTORIA
LAS TICS, LA IMAGEN Y LAS CIENCIAS SOCIALES. ALGUNAS EXPERIENCIAS Y REFLEXIONES
Authors: Barrenetxea Marañón Igor
Published: November 2024

Este artículo pretende ser una reflexión y una invitación al impulso de las TICs en las Ciencias Sociales. En él se valoran las ventajas y desventajas de las TICs, la importancia de Internet en la búsqueda de información, y se presentan tres actividades (WebQuest, Pizarra Digital y Blog) que se pueden incorporar en la programación educativa de manera plena y activa, así como el tratamiento de la imagen (a través del cine).
La presencia educativa del patrimonio inmaterial: análisis comparados de los currículos de Chile y España.
Authors: Admin Admin , Rubio-Navarro Alodia , Rivero Pilar , García-Ceballos Silvia
Published: November 2024

Pese a larga trayectoria de la Educación Patrimonial en Iberoamérica,la didáctica de las manifestaciones inmateriales del patrimonio apenas hasido atendida y son escasas las publicaciones sobre las particularidades de susprocesos de enseñanza-aprendizaje. Para abordar estas, ha de considerarsepreviamente qué planteamiento didáctico se hace en el currículo educativopara trabajar el patrimonio inmaterial. Por ello, se realiza una revisión de losdocumentos curriculares español y chileno con objeto de evaluar la presenciay el tratamiento del patrimonio intangible en la educación formal. La metodologíaaplicada consiste en el análisis de contenido de los currículos dela Educación Primaria en España y la Básica en Chile. Se comparan ambostextos para detectar similitudes y divergencias, considerando que estas puedenser un factor determinante en las diferentes perspectivas que docentesy estudiantes sostienen sobre el patrimonio inmaterial en ambos países. Losresultados demuestran que el currículo chileno concede mayor presencia a lasmanifestaciones intangibles al entenderlas como un elemento fundamentalpara la conformación de la identidad nacional, si bien en ambos países son necesariosuna mayor integración de estos contenidos en las diversas asignaturasescolares y un enfoque más orientado hacia lo procedimental y lo transmisivo.
Is 26S proteasome non-ATPase regulatory subunit 6 a potential molecular target for intrahepatic cholangiocarcinoma?
Authors: Zhuang Yong-Zhi , Tong Li-Quan , Sun Xue-Ying
Published: November 2024

In this editorial we comment on the article by Tang et al published in the recent issue of World Journal of Hepatology . Drug therapy of intrahepatic cholangiocarcinoma (iCCA) poses an enormous challenge since only a small proportion of patients demonstrate beneficial responses to therapeutic agents. Thus, there has been a sustained search for novel molecular targets for iCCA. The study by Tang et al evaluated the role of 26S proteasome non-ATPase regulatory subunit 6 (PSMD6), a 19S regulatory subunit of the proteasome, in human iCCA cells and specimens. The authors employed clustered regularly interspaced short palindromic repeat (CRISPR) knockout screening technology integrated with the computational CERES algorithm, and analyzed the human protein atlas (THPA) database and tissue microarrays. The results show that PSMD6 is a gene essential for the proliferation of 17 iCCA cell lines, and PSMD6 protein was overexpressed in iCCA tissues without a significant correlation with the clinicopathological parameters. The authors conclude that PSMD6 may play a promoting role in iCCA. The major limitations and defects of this study are the lack of detailed information of CRISPR knockout screening, in vivo experiments, and a discussion of plausible mechanistic cues, which, therefore, dampen the significance of the results. Further studies are required to verify PSMD6 as a molecular target for developing novel therapeutics for iCCA. In addition, the editorial article summarizes the latest advances in molecular targeted drugs and recently emerging immunotherapy in the clinical management of iCCA, development of proteasome inhibitors for cancer therapy, and advantages of CRISPR screening technology, computational methods, and THPA database as experimental tools for fighting cancer. We hope that these comments may provide some clues for those engaged in the field of basic and clinical research into iCCA.
Autoimmune hepatitis: Towards a personalized treatment
Authors: Costaguta Alejandro , Costaguta Guillermo , Álvarez Fernando
Published: November 2024

Autoimmune hepatitis is an uncommon condition that affects both adults and children and is characterized by chronic and recurrent inflammatory activity in the liver. This inflammation is accompanied by elevated IgG and autoantibody levels. Historically, treatment consists of steroids with the addition of azathioprine, which results in remission in approximately 80% of patients. Despite significant advancements in our understanding of the immune system over the past two decades, few modifications have been made to treatment algorithms, which have remained largely unchanged since they were first proposed more than 40 years ago. This review summarized the various treatment options currently available as well as our experiences using them. Although steroids are the standard treatment for induction therapy, other medications may be considered. Cyclosporin A, a calcineurin inhibitor that decreases T cell activation, has proven effective for induction of remission, but its long-term side effects limit its appeal for maintenance. Tacrolimus, a drug belonging to the same family, has been used in patients with refractory diseases with fewer side effects. Sirolimus and everolimus have interesting effects on regulatory T cell populations and may become viable options in the future. Mycophenolate mofetil is not effective for induction but is a valid alternative for patients who are intolerant to azathioprine. B cell-depleting drugs, such as rituximab and belimumab, have been successfully used in refractory cases and are useful in both the short and long term. Other promising treatments include anti-tumor necrosis factors, Janus kinases inhibitors, and chimeric antigen receptor T cell therapy. This growing armamentarium allows us to imagine a more tailored approach to the treatment of autoimmune hepatitis in the near future.
Diagnostic value of tissue plasminogen activator-inhibitor complex in sepsis-induced liver injury: A single-center retrospective case-control study
Authors: Zhou Ye , He Long-Ping , Qi Ying-Han , Huang Yu , Hu Bing-Qin , Liu Jia-Ling , Zeng Qing-Bo , Song Jing-Chun
Published: November 2024

BACKGROUND

Sepsis often causes severe liver injury and leads to poor patient outcomes. Early detection of sepsis-induced liver injury (SILI) and early treatment are key to improving outcomes.

AIM

To investigate the clinical characteristics of SILI patients and analyze the associated risk factors, to identify potential sensitive biomarkers.

METHODS

Retrospective analysis of clinical data from 546 patients with sepsis treated in the intensive care unit of the 908th Hospital of Chinese People’s Liberation Army Joint Logistic Support Force between May 2018 and December 2022. The patients were divided into the sepsis group (n = 373) and SILI group (n = 173) based on the presence of acute liver injury within 2 hours of admission. We used the random forest algorithm to analyze risk factors and assessed potential diagnostic markers of SILI using the area under the receiver operating characteristic curve, Kaplan-Meier survival curves, subgroup analysis and correlation analysis.

RESULTS

Compared with the sepsis group, tissue plasminogen activator-inhibitor complex (t-PAIC) levels in serum were significantly higher in the SILI group (P < 0.05). Random forest results showed that t-PAIC was an independent risk factor for SILI, with an area under the receiver operating characteristic curve of 0.862 (95% confidence interval: 0.832-0.892). Based on the optimal cut-off value of 11.9 ng/mL, patients at or above this threshold had significantly higher levels of lactate and Acute Physiology and Chronic Health Evaluation II score. The survival rate of these patients was also significantly worse (hazard ratio = 2.2, 95% confidence interval: 1.584-3.119, P < 0.001). Spearman’s correlation coefficients were 0.42 between t-PAIC and lactate, and 0.41 between t-PAIC and aspartate transaminase. Subgroup analysis showed significant differences in t-PAIC levels between patients with different severity of liver dysfunction.

CONCLUSION

T-PAIC can serve as a diagnostic indicator for SILI, with its elevation correlated with the severity of SILI.
Sensitivity of diagnosis of spontaneous bacterial peritonitis is higher with the automated cell count method
Authors: Acevedo-Haro Juan G , Mohamed Waddah , Moodley Prebashan , Bendall Oliver , Bennett Kris , Keelty Nigel , Chan Sally , Waddy Sam , Hosking Joanne , Thomas Wayne , Tilley Robert
Published: November 2024

BACKGROUND

Spontaneous bacterial peritonitis (SBP) is one of the most important complications of patients with liver cirrhosis entailing high morbidity and mortality. Making an accurate early diagnosis of this infection is key in the outcome of these patients. The current definition of SBP is based on studies performed more than 40 years ago using a manual technique to count the number of polymorphs in ascitic fluid (AF). There is a lack of data comparing the traditional cell count method with a current automated cell counter. Moreover, current international guidelines do not mention the type of cell count method to be employed and around half of the centers still rely on the traditional manual method.

AIM

To compare the accuracy of polymorph count on AF to diagnose SBP between the traditional manual cell count method and a modern automated cell counter against SBP cases fulfilling gold standard criteria: Positive AF culture and signs/symptoms of peritonitis.

METHODS

Retrospective analysis including two cohorts: Cross-sectional (cohort 1) and case-control (cohort 2), of patients with decompensated cirrhosis and ascites. Both cell count methods were conducted simultaneously. Positive SBP cases had a pathogenic bacteria isolated on AF and signs/symptoms of peritonitis.

RESULTS

A total of 137 cases with 5 positive-SBP, and 85 cases with 33 positive-SBP were included in cohort 1 and 2, respectively. Positive-SBP cases had worse liver function in both cohorts. The automated method showed higher sensitivity than the manual cell count: 80% vs 52%, P = 0.02, in cohort 2. Both methods showed very good specificity (> 95%). The best cutoff using the automated cell counter was polymorph ≥ 0.2 cells × 109/L (equivalent to 200 cells/mm3) in AF as it has the higher sensitivity keeping a good specificity.

CONCLUSION

The automated cell count method should be preferred over the manual method to diagnose SBP because of its higher sensitivity. SBP definition, using the automated method, as polymorph cell count ≥ 0.2 cells × 109/L in AF would need to be considered in patients admitted with decompensated cirrhosis.