bluuebunny/crossref_metadata_2025 huggingface dataset:
Characterizing mobility patterns of forest goersin southern Lao PDR using GPS loggers.
Authors: Rerolle Francois , Dantzer Emily , Phimmakong Toula , Lover Andrew , Hongvanthong Bouasy , Phetsouvanh Rattanaxay , Marshall John , Sturrock Hugh , Bennett Adam
Published: May 2022

Background: In the Greater Mekong Subregion (GMS), forest-going populations are considered high-risk populations for malaria and are increasingly targeted by national control programs’ elimination efforts. A better understanding of forest-going populations’ mobility patterns and risk associated with specific types of forest-going trips is necessary for countries in the GMS to achieve their objective of eliminating malaria by 2030.Methods: Between March and November 2018, as part of a focal test and treat intervention (FTAT), we recruited 2,904 forest-goers in southern Lao PDR. A subset of forest-goers carried an “i-Got-U” GPS logger for roughly two months, configured to collect GPS coordinates every 15 to 30 minutes. The utilization distribution (UD) surface around each GPS trajectory was used to extract trips to the forest and forest-fringes. Trips with shared mobility characteristics in terms of duration, timing and forest penetration were identified by a hierarchical clustering algorithm. Then, clusters of trips with increased exposure to dominant malaria vectors in the region were further classified as high-risk. Finally, we used gradient boosting trees to assess which of the forest-goers’ socio-demographic and behavioral characteristics best predicted their likelihood to engage in such high-risk trips. Results: A total of 122 forest-goers accepted carrying a GPS logger resulting in the collection of 803 trips to the forest or forest-fringes. Six clusters of trips emerged, helping to classify 385 (48%) trips with increased exposure to malaria vectors based on high forest penetration and whether the trip happened overnight. Age, outdoor sleeping structures and number of children were the best predictors of forest-goers’ probability of engaging in high-risk trips. The probability of engaging in high-risk trips was high (~33%) in all strata of the forest-going population.Conclusion: This study characterized the heterogeneity within the mobility patterns of forest-goers and attempted to further segment their role in malaria transmission in southern Lao People’s Democratic Republic (PDR). National control programs across the region can leverage these results to tailor their interventions and messaging to high-risk populations and accelerate malaria elimination.
Directions of tourism development in cross-border mountain territories
Authors:   Novosibirsk State University of Economics and Management, Novosibirsk, Glotko A. , Shelkovnikov S. ,   Novosibirsk State Agrarian University, Novosibirsk, Kuznetsova I. ,   Novosibirsk State Agrarian University, Novosibirsk
Published: May 2022

The article is devoted to the development of new approaches to the development of tourism in cross-border mountain territories. The object of the research is tourism in the cross-border mountain territories of the Altai-Sayan region. The subject of the research is the prospects of tourism development in the cross-border mountain territories. The aim of the research is to develop new approaches to the development of tourism in the cross-border mountain territories. The aim of the research is to consider a system of indicators to assess the level of tourism development, the efficiency of tourist and recreational potential use, the impact of tourist and recreational activities on the socio-economic development of cross-border mountain territories and to formulate proposals for the sustainable development of tourism in cross-border mountain territories. The features of mountainous territories, including those with a cross-border situation, determining the specifics of tourist and recreational activities are systematized. The factors influencing the tourist and recreational activity of mountain territories are revealed. A system of indicators for assessing the level of tourism development of cross-border mountain territories, a system of indicators for assessing the impact of tourism on the socio-economic development of cross-border mountain territories is disclosed. The analysis of tourism development of the trans-boundary mountain territories of the Altai-Sayan region is carried out. Recommendations and practical proposals for the sustainable development of tourism in cross-border mountain territories have been formed
ANALYSIS OF THE CURRENT SITUATION IN THE RUSSIAN SHIPBUILDING MARKET
Authors:   Saint Petersburg State Marine Technical University, Saint Petersburg, Nesnova, M.
Published: May 2022

Shipbuilding is one of the most complex and labor-intensive branches of the heavy industry in Russia. It includes production of civil ships, warships, marine facilities, as well as ship repair. The object of this research is the market of civil ships. Transport ships, icebreakers and marine equipment created for the Arctic shelf development are observed in the article. Since the development of mechanical engineering, especially shipbuilding is strategically important against the aggravated political situation, the current trends, dynamics, state support, production capacities, sales markets and technologies of the Russian civil shipbuilding market are considered as the subject of the research in order to assess the possibility of import substitution within the country. Research Methodology and Methods: A complex approach has been used for the research - marketing research on the basis of SWOT-analysis, Big Data and statistical information from open sources. The work has traced the stages from the general analysis of the whole shipbuilding industry, to the indicators for individual types of ships. As a result of the research three different results are obtained. Among the main ones the following ones can be singled out: Russia has lost competitiveness in the global market of transport ships; the acute need for ships in the domestic market, due to the moral and physical deterioration of the fleet and the growing demand for inland waterways; lack of an algorithm for collecting and processing data in a single system to optimize the work; currently work in shipbuilding does not allow the use of artificial intelligence; domestic shipbuilding is experiencing the effects of sanctions introduced in 2014; demand for transport ships has a steady upward trend. In the course of the research, two options for business optimization have been developed: vertical and horizontal, which involve the creation of a unified IT platform and full digitalization of all processes in the shipbuilding industry. The results of the research can be a basis for working out unified strategy of marine equipment development for the Arctic exploration where nomenclature, standard sizes and use of domestic shipboard equipment will be substantiated. The shipbuilding industry development in Russia is necessary for infrastructure formation, organization and support of work on the shelf, passenger transportation, creation of conditions for improvement of the national defense potential, growth of related industries: radio engineering, metallurgy and composite materials, electronics, which in turn affects job creation.
RUSSIAN-CHINESE ECONOMIC COOPERATION IN THE CONCEPT OF GLOBAL DIGITALIZATION
Authors:   Russian Customs Academy, Vladivostok Branch, Ostanin, V. , Pecheritsa V. ,   Far Eastern Federal University, Oriental Institute – School of Regional and International Studies, Boyarkina, A. ,   Far Eastern Federal University, Oriental Institute – School of Regional and International Studies
Published: May 2022

The article is devoted to the analysis of the formation on the territory of Eurasia of an international credit and financial institution, which has some common features with the International Monetary Funds, on the basis of partnership with the participation of China, India, Pakistan, Iran and other countries. This international integration financial and credit institution can become a reality only on the basis of the general global digitalization of the countries that are members of the union. This integral community will remain open to other states. The contradictions that arise during international integration can receive their civilized forms of resolution in the model of the conflict-compromise paradigm. This formulation of the problem of the formation of an international financial and credit institution in the territory of responsibility of the countries of Southeast Asia, Russia, the countries of the Eurasian Economic Union made it possible to finally undermine the position of the US dollar in international settlements. The purpose and objectives of the study are to reveal the global trend in the formation of a new financial and economic reality in the context of increasing activity in the formation of a single digital space, switching to settlements in national currencies and switching to digital currency means of payment in settlements, and in the future, to global reserve digital payment instruments facilities. The object of the study is the regional financial and credit system, which is capable of reducing the risks of losses of foreign exchange funds from the implementation of the hostile sanctions policy of other states, primarily the United States. The subject of the study is the model for creating global means of payment based on digital currency means of payment of countries that are members of the Union of Southeast Asian countries, Russia, as well as other countries wishing to join the Union. The conclusions obtained have scientific and practical value as a result of sufficient verification, provided by the use of modern scientific research methods, including historical and logical, comparative analysis, methods of scientific induction, comparative analysis. The use of a comparative-functional, systematic approach makes it possible to obtain results that have a sufficient evidence-based, methodological basis in the formation of the Eurasian Monetary Fund. The analysis of modern economic and political literature testifies to the recognition of a large theoretical and practical problem regarding the new architecture of economic, financial, and monetary relations within the framework of the proposed future model of the Eurasian Payments Union
The phenomenon of pulsating lakes of Torey (Transbaikalia)
Authors:   Transbaikal State University, Chita, Salikhov V.
Published: May 2022

The phenomenon of pulsating lakes of the drainless Torey Basin - Barun- and Zun-Torey, located in the south of Transbaikalia territory, is considered. The unique peculiarity of the lakes is periodicity, mainly alternation of distinctly dry and wet periods with the duration of 24 to 42 years, on average about 30 years, i.e. a strict cyclicity is not observed. The cause of periodicity is measured from two main positions: either climatic changes or tectonic processes. The analysis of the available material indicates that the cause of periodicity is complex, but with the leading role of tectonic processes (neotectonic fluctuations), awakening multilevel groundwater of the Tsasucheisky and Torey artesian basins are the main sources of lake feeding. Groundwater feeding (Uldza River, Imalka River) is insignificant and the inflow is spent for evaporation. Tectonic processes do not occur without the participation of the Space (solar activity, the state of the Universe), because the Earth is a coordinated space system and all the processes occurring in it are reflected in the state of its depths. Measures are suggested to change considerably the duration of oscillations of the water surface of the Torey lakes and not to wait for the next water period of 15 years and more. Such measures can be compulsory influence on the activity of a lot of underground waters of the artesian basin, the main sources of feeding of the lakes. External influences can be ground or underground dosed explosions or vibration (during desiccation phases), widely used to increase the oil and gas flow rate in hydrocarbon production. Another remarkable phenomenon of the Torey Basin is mud volcanism in a form of salsa, which some researchers consider as search signs of oil and gas bearing capacity. The analysis of materials on mud volcanism on a global scale unequivocally indicates the absence of mud volcanism not only in the Torey Basin, but also in general the absence of such in Transbaikalia. The phenomenon of pulsating Torey lakes is not related to climatic changes, but has a complex cause, with the leading end, the "piston pump" effect, not without the participation of the Space. There is no mud volcanism in the Torey Basin. Consequently, it is not necessary to speak about its prospects for oil-and-gas bearing capacity. The salts observed in the Torey have a different nature and are connected with the activity of groundwater in the areas of permafrost spreading
Studies of the various reagents effect on the efficiency of underground borehole leaching of uranium from the ores of the Khiagdinsky deposit
Authors:   Transbaikal State University, Doctor of Technical Sciences, Professor, Chita, Ovseychuk V. , Mikhailov A. ,   Transbaikal State University, post graduate student, Chita
Published: May 2022

To ensure Russia's energy security, it is necessary to produce cheap electricity. One of the directions of domestic energy development is its production at nuclear power plants. The source of raw materials for powering nuclear reactors is natural uranium extracted from rocky and hydrogenic (localized in loose sediments) deposits. Hydrogenic deposits have been explored in Transbaikalia, united into a single Khiagdin ore field and characterized by identical mining-geological, hydrogeological and technological parameters. During the operation, certain difficulties have been identified in the extraction of natural uranium, related both to the geological structure of the deposits and the temperature regime of groundwater, and to the economic performance of the enterprise. As a result of the confluence of these circumstances, the issue of transferring uranium to a mobile state during underground borehole leaching with the necessary dynamics that ensures the concentration of uranium in a productive solution, the processing of which will produce profitable mining enterprise products, is problematic. This article is devoted to the intensification of the leaching process using chemical activators that accelerate the conversion of uranium into a productive solution The relevance of the work is due to the need to activate the process of uranium leaching with the help of underground borehole leaching to ensure a more complete recovery of uranium and to reduce the period of field development with the use of chemical oxidants. The object of the study is technological processes of underground in-situ leaching with the use of chemical activators. The purpose of the study is improving the development efficiency of hydrogenous uranium deposits, reducing operating costs. The research objectives are to identify the most effective oxidants and regimes of their use, increasing the volume of uranium recovery in the productive solution. The research methodology included collecting information, its mathematical and statistical processing, carrying out research work and establishing a connection between mining-geological, hydrogeological and technological parameters of ore leaching. Research methods: mathematical and statistical analysis, laboratory research and the use of the results for experimental and industrial works
STUDY OF MINERALOGICAL AND TEXTURAL-STRUCTURAL FEATURES OF OLD WELTZ-CLINKER
Authors:   Nosov Magnitogorsk State Technical University, Magnitogorsk, Orekhova N. , Glagoleva I. ,   Nosov Magnitogorsk State Technical University, Magnitogorsk, Efimova J. ,   Nosov Magnitogorsk State Technical University, Magnitogorsk, Gorlova O. ,   Nosov Magnitogorsk State Technical University, Magnitogorsk
Published: May 2022

The chemical, mineralogical and phase composition of clinker from zinc cakes is analyzed. An analysis of the properties of the main components of the Waelz-clinker is carried out. It has been established that the mass fraction of copper in it is comparable to its mass fraction in sulfide ores, in connection with this, clinker is considered as a raw iron-containing, copper-containing, zinc-containing and carbon-containing material. The existing methods of clinker enrichment are analyzed. The features of the textural and structural composition of the old clinker of the Chelyabinsk zinc plant are investigated and the use of mechanical and physico-chemical separation methods for different phases of the clinker is substantiated. To study the material composition of clinker, a complex of mineralogy and analytical methods is used, including optical microscopy, electron microscopy and X-ray spectral analysis. As a result of studying the phase and mineralogical compositions of clinker, it has been found that some of the iron-containing phases, the atomic composition of which is close to the composition of pyrite-pyrrhotite type minerals, is represented by troilite. The possibility of troilite formation in the Waelz process is substantiated. Electron microscopic analysis confirmed that the copper-rich phases identified during the mapping of the surface of the thin section at high magnification consist of copper sulfides dispersed in the spinel or mellilite matrix with a size of less than 15 μm. The composition of the relatively rich zinc-containing phases is predominantly represented by ferruginous sphalerite (marmatite) and zinc ferrite. The results of a comprehensive study of the structural and phase characteristics of clinker showed the need to include gravity separation in the plan of research on the washability of gravitational separation in order to more fully release iron into concentrate and flotation of finely divided clinker in order to increase the recovery of copper and zinc-containing phases
METHOD OF DYNAMIC MEASUREMENTS AND OPTIMAL ASSESSMENT OF THE PENETRATION DEGREE OF MARINE SALT AEROSOL INTO COASTAL PRODUCTION ZONES
Authors:   National Academy of Aviation, Baku, Khalilova Kh
Published: May 2022

An accurate assessment of the emission of pollutants coming from the water surface is extremely relevant in studies of mass transfer between the sea and the atmosphere. The object of the study is a corrosive marine salt aerosol formed under the influence of wind, as a result of the dissipation of wave energy when hitting the shore. The subject of the study is the extent of the spread of sea salt aerosol under the influence of wind in coastal residential and industrial zones. The purpose of the study is to determine the nature of the change in wind speed over time, at which the total measuring signal at the output of the mobile meter would reach an extreme, i.e. the most reliable measurement result would be achieved. The aim of the study, when comparing the increasing and decreasing wind speeds, to determine such a dependence of wind speed on the current measurement time at which the measurement result would reach an extremum. The general task of estimating the amount of corrosive sea aerosol deposited in the coastal zone in this case is to estimate the amount of the current unsettled aerosol in the air. The proposed research method is to determine the penetration degree of sea salt aerosol into residential and industrial quarters, a dynamic measurement method is proposed, carried out using a mobile laboratory equipped with appropriate measuring equipment. The meter at point xi measures the aerosol generated by the wind at moment ti . For the optimal solution of the problem, the double averaging method is used. As a result a mobile measurement method is proposed to determine the degree of penetration of marine salt aerosol into the coastal production zone. The problem of determining the nature of the temporary change in wind speed in the coastal zone is solved with a known dependence of the amount of settled sea aerosol on the distance between the measuring point and the sea under the condition of a constant speed of movement of the mobile meter
An effective field theory of magneto-elasticity
Authors: Pavaskar Shashin , Penco Riccardo , Rothstein Ira
Published: May 2022

We utilize the coset construction to derive the effective field theory of magnon-phonon interactions in (anti)-ferromagnetic and ferrimagnetic insulating materials. The action is used to calculate the equations of motion which generalize the
Landau-Lifshitz and stress equations to allow for magneto-acoustic couplings to all orders in the fields at lowest order in the derivative expansion. We also include the symmetry breaking effects due to Zeeman, and Dzyaloshinsky-Moriya interactions. This effective theory is a toolbox for the study of magneto-elastic
phenomena from first principles. As an example we use this theory to calculate the leading order contribution to the magnon decay width due
to its the decay into phonons.
Quantitative functional renormalization for three-dimensional quantum Heisenberg models
Authors: Niggemann Nils , Reuther Johannes , Sbierski Björn
Published: May 2022

We employ a recently developed variant of the functional
renormalization group method for spin systems, the so-called pseudo
Majorana functional renormalization group, to investigate
three-dimensional spin-1/2 Heisenberg models at finite temperatures. We
study unfrustrated and frustrated Heisenberg systems on the simple cubic
and pyrochlore lattices. Comparing our results with other quantum
many-body techniques, we demonstrate a high quantitative accuracy of our
method. Particularly, for the unfrustrated simple cubic lattice
antiferromagnet ordering temperatures obtained from finite-size scaling
of one-loop data deviate from error controlled quantum Monte Carlo
results by \sim5\%∼5%
and we confirm consistency of our data with established critical
exponents \nuν
and \etaη
of the three-dimensional Heisenberg universality class. As the PMFRG
yields results in good agreement with QMC, but remains applicable when
the system is frustrated, we next treat the pyrochlore Heisenberg
antiferromagnet as a paradigmatic magnetically disordered system and
find nearly perfect agreement of our two-loop static homogeneous
susceptibility with other methods. We further investigate the broadening
of pinch points in the spin structure factor as a result of quantum and
thermal fluctuations and confirm a finite width in the extrapolated
limit T\rightarrow0T→0.
While extensions towards higher loop orders
\ellℓ
seem to systematically improve our approach for magnetically disordered
systems we also discuss subtleties when increasing
\ellℓ
in the presence of magnetic order. Overall, the pseudo Majorana
functional renormalization group is established as a powerful many-body
technique in quantum magnetism with a wealth of possible future
applications.
Fe@Fe2O3-loaded biochar as an efficient heterogeneous Fenton catalyst for organic pollutants removal
Authors: Chen Diwei , Zheng Zhiyan , Zhang Feiji , Ke Rufu , Sun Nan , Wang Yonghao , Wang Yongjing
Published: May 2022

With increased demand for various chemical raw materials, sudden pollution incidents are more prone to occur during their transportation and usage, threatening the environment and human health. In this study, discarded tea stalks were recycled into composite materials (FSC-X00: X represents the calcination temperature) by impregnating tea stalks in Fe2+ solution combined with subsequent calcination. X-ray diffractometer (XRD) and X-ray photoelectron spectroscopy (XPS) patterns verified the existence of Fe0 and Fe2O3, and Fe2O3 was gradually reduced to Fe0 when the calcination temperature was raised from 700 °C to 900 °C. FSC-X00 was adopted as a heterogeneous catalyst for activating H2O2 to quickly degrade phenol in the water system. The degradation experiments indicated that FSC-600 exhibited superior degradation performance for phenol (20 mg/L) within 5 min and 80% total organic carbon (TOC) removal rate at pH = 3 within 30 min. The effects of the calcination temperature, the pH value and the amount of H2O2 on the degradation efficiency were investigated. Competing experiments showed that fulvic acid (FA) and inorganic salts Na+ had little effect on the degradation performance. The FSC-600 catalyst can be reused by thermal reduction. In addition, it was found that FSC-600 has a good degradation effect on ciprofloxacin (CIP), norfloxacin (NOR) and enrofloxacin (ENR), indicating that FSC-600 catalysts are a promising candidate for quick degradation of organic pollutants by Fenton reaction. Electron paramagnetic resonance (EPR) spectra analysis indicated that •OH is the dominant reactive oxygen species (ROS) and part 1O2 from O2 also participated in the degradation. This study provides an example of creating catalysts from organic solid waste for use in emergency treatment for phenol.
The Coupling of Carbon and Nitrogen Substituents with Nitroarenes: Vicarious
Nucleophilic Substitution of Hydrogen in Nitroarenes
Authors: Zou Dong , Han Gang
Published: May 2022

In recent years, nitroarenes have been extensively exploited as green, efficient
electrophilic arylation reagents used in a variety of organic syntheses. Transition-metal-free
cross-coupling reactions and vicarious nucleophilic substitution (VNS) have become practical
and reliable synthetic methods to access momentous functionalized organic compounds. Thus,
the introduction of various substituents into nitroarenes has attracted considerable attention as
important synthetic approaches due to their simplicity and practicality. In this review, we
comprehensively summarize the coupling of several carbon and nitrogen substituents with
nitroarenes via nucleophilic substitution under mild conditions, followed by the application of
these transversions in the construction of carbon and heterocyclic rings.
Super Para-Magnetic Iron Oxide Nanoparticles (SPIONs) in the Treatment
of Cancer: Challenges, Approaches, and its Pivotal Role in Pancreatic,
Colon, and Prostate Cancer
Authors: Khan Sameea Ahmed , Sharma Rajesh
Published: May 2022

Super Para-magnetic Iron Oxide Nanoparticles (SPIONs) have been manifested for their
broad spectrum of applications ranging from biomedical imaging to the treatment of many diseases.
Many experiments are being conducted across the globe to especially investigate their potential in the
field of targeted treatment for malignant tissues. However, challenges pertaining to the desired delivery
of anticancer drugs in the body remain unresolved or unattended. The bare iron oxide nanoparticles are
liable to form agglomerates or get easily oxidized in the air which can lead to loss of their magnetism
and viability. Moreover, in several reactions, these magnetic nanoparticles leach into the solution/ suspension,
making it kinetically unstable. The nanoparticles, further readily metabolize in the stomach pH
or are phagocytosed by macrophages. In this article, we address these issues by shedding light on the
impact of controlling parameters like size, synthesis method, and surface engineering. After studying the
existing literature, it is noted that currently, these magnetically guided delivery systems are being rigorously
tested in areas like pancreatic cancer, colon cancer, and prostate cancer, which will be discussed
in this review. The fact that the major issue in the conventional treatment of these cancers is intrinsic
and acquired drug resistance is a key issue. In this context, the potential of SPIONs as efficient nanotherapeutics
is presented. The article provides a deeper insight into the research conducted on these
focused areas in cancer. This review also discusses, in brief, the consolidation of artificial intelligence in
cancer nanomedicine assuring a better treatment outcome in near future.
Recent Developments in the Synthesis and Anticancer Activity of Indole
and Its Derivatives
Authors: Wadhwa Pankaj , Kaur Balwinder , Venugopal Sneha , Verma Anil , Sahu Sanjeev Kumar , Kumar Deepak , Sharma Ajit
Published: May 2022

Heterocyclic compounds are a class of compounds that is deeply intertwined with biological
processes and is found in about 90% of commercially available medicines. They serve a
critical function in medicinal chemistry and are focused in the field of medication development for
their intensive research due to their broad variety of biological effects because of their intriguing
molecular architecture, such as indoles are good candidates for drug development. It is a bicyclic
structure consisting of a six-membered benzene ring fused to a five-membered pyrrole ring with
several pharmacophores that yield a library of different lead compounds. Human cancer cells have
been demonstrated to be inhibited by indoles in the development of new anticancer medicines.
This is the first comprehensive review to focus on current methodologies for incorporating indole
moiety, with their mechanistic targets as anticancer drugs, in order to shed light on the logical development
of indole-based anticancer treatment options with high efficacy. This compiled data
may serve as a benchmark for modifying existing ligands in order to design novel potent molecules
through excellent yield synthesis techniques.
Transformation in Content of Bioactive Compounds of Glodok Fish (Boleopthalmus boddarti) Based on the Effect of Variations in Temperature and Frying Time
Authors: Ridho Moh. Rasyid , Patriono Enggar , Cahyani Ajeng , Avesena Muhammad , Fitria Syarifa
Published: May 2022

Objective: One species of glodok fish is Boleophthalmus boddarti. The fish was identified to contain bioactive compounds such as steroids, terpenoids, bufadienolid, carotatoksin, and corticosteroids. Bioactive compounds have benefits for human life. Methods: Lampung coastal communities consume glodok fish to cure asthma. They consume glodok fish by various processing methods, such as by frying. The frying process is expected to damage some nutrients such as vitamins and proteins, including the possibility of damaging bioactive compounds. However, there is no data regarding the effect of using different temperatures and times in the frying process on changes in bioactive content in the meat of the glodok fish. Sampling was carried out around the mouth of the Musi River, South Sumatra. The stages of the research consisted of the preparation process, treatment using 9 variations of temperature and frying time, sample extraction, analysis of the content of bioactive compounds by GC-MS. Results: The results showed that the bioactive compounds identified before fried fishes consisted of corticosteroids, steroids, carotenoids, monoterpenoids, sesquiterpenoids, and triterpenoids. Conclusion: Variations in the treatment resulted in cholesterol of the steroid group in the highest treatment at 14.36% and the loss of betamethasone acetate compounds in the corticosteroid group by 0.07% in the treatment sample.
Complete Healing of a Heel Bedsore using Argania Honey Dressing: Case
Report
Authors: Raghay Kawtar , Khattabi Leila , Dakkach Mohamed , Allouch Mohamed
Published: May 2022

Background:

Chronic wounds and injuries represent a significant burden for health care
professionals due to the difficulties related to their management. The selection and use of appropriate
dressings have become essential for successful treatment. Honey has been used for thousands of
years as a biological treatment because its bioactive components contribute to the healing process.

Objective:

This case report aims to demonstrate the efficiency of Argania honey dressing on pressure
ulcers.

Case Presentation:

The wound care was achieved using pure raw Argania honey with no additives,
pasteurization, or manipulation. A previous mechanical debridement process was necessary before
the application of honey dressings to a right heel bedsore in a 69-year-old man who suffered an ischemic
stroke.

Results:

This case report describes for the first time the complete healing of a right heel bedsore using
Argania honey dressing. Bedsore demonstrated rapid recovery and complete healing over approximately
18 weeks (124 days, between June and October 2021).

Conclusion:

With the rise of natural medicines and some pathologies that are resistant to conventional
treatments, Argania honey can be an asset for its therapeutic effects on the skin, but more
studies are needed to explain and identify the complexity of mechanisms involved to ensure this
complete healing process.
Parotid Gland Swelling as an Initial Presentation of Multiple Myeloma: A
Case Report
Authors: Singh Jitendra , Dewangan Ankita , Singh Swati , Kumar Nilesh , Kumar Kailash
Published: May 2022

Introduction:

Parotid swellings are commonly encountered in ENT Clinics, the cause of which could range from neural conditions, endocrine problems, vitamin deficiencies, and sialadenitis, which may even be a manifestation of an underlying systemic disease. Multiple myeloma represents a clonal proliferation of plasma cells and is a condition in which a parotid swelling might be present, although very uncommon.

Case presentation:

We report a case of 60-year-old female presented with unilateral parotid swelling, which led to a diagnosis of multiple myeloma based on the investigations.

Conclusion:

Various imaging modalities are currently available to assess the extent of the swelling and evaluate the soft tissue and osseous involvement. The clinician must have a rigorous insight into the several clinical manifestations and the sites of involvement of the different conditions to make a proper diagnosis.
Effects of Semaglutide on Glycemic Control and Weight Loss in a Patient with Prader-Willi Syndrome: A Case Report
Authors: Sani Elena , Prato Giuliana Da , Zenti Maria Grazia , Bordugo Andrea , Trombetta Maddalena , Bonora Enzo
Published: May 2022

Background:

Prader-Willi syndrome is the most frequent genetic cause of obesity and is
often complicated by glucose metabolism alterations. Conventional therapies prescribed for type 2
diabetes frequently failed to achieve adequate glycemic control in patients with Prader-Willi
syndrome. Beneficial effects of glucagon like peptide-1 receptor agonists exenatide and liraglutide
have been reported for the management of type 2 diabetes in Prader-Willi syndrome, but no data
are currently available in this population on the use of semaglutide.

Case Presentation:

We report for the first time the use of semaglutide 1 mg per week in a 33-yearold
man with Prader-Will syndrome complicated by poorly controlled diabetes and severe obesity.
After 12 months of semaglutide treatment, we observed an important reduction in glycated
hemoglobin levels (11.1% to 7.2%) and body weight (99.5 kg to 94.3 kg), with a notable decrease
in fat mass and insulin requirements. Interestingly, our patient had already tried liraglutide therapy
in adjunction to metformin and insulin therapy, reporting no substantial efficacy.

Conclusions:

The beneficial effects of semaglutide on glycemic control and weight reduction
provide a promising treatment for diabetes and obesity in Prader-Willi syndrome, even where other
glucagons like peptide-1 receptor agonists have failed. Further studies are required to confirm the
efficacy and safety of semaglutide in patients with Prader-Willi syndrome.
Antidiabetic Phytocompounds Acting as Glucose Transport Stimulators
Authors: Eddouks Mohamed , Akdad Mourad , Ameziane Rabii , Khallouki Farid , Bakri Youssef
Published: May 2022

Aims:

The present study aimed to provide summarized data related to the phytocompouds improving glucose uptake in the diabetic state.

Background:

Glucose uptake in peripheral tissues such as skeletal muscle and adipose tissue is considered as an important step in the regulation of glucose homeostasis. Reducing high blood glucose levels in diabetic patients via targeting peripheral glucose uptake is a promising strategy to develop new antidiabetic medications derived from natural products.

Objective:

The current review focused on antidiabetic natural phytocompounds acting on glucose uptake in adipocytes and skeletal muscles to highlight their phytochemistry, the mechanistic pathway involved, toxicity, and clinical assessment.

Methods:

A systematic search was conducted in the scientific database with specific keywords on natural phytocompounds demonstrated to possess glucose uptake stimulating activity in vitro or ex vivo during the last decade.

Results:

In total, 195 pure molecules and 7 mixtures of inseparable molecules isolated from the plants kingdom, in addition to 16 biomolecules derived from non-herbal sources, possess a potent glucose uptake stimulating capacity in adipocytes and/or skeletal muscles in adipocytes and/or skeletal muscles in vitro or ex vivo. Molecular studies revealed that these plant-derived molecules induced glucose uptake via increasing GLUT-4 expression and/or translocation through insulin signaling pathway, AMPK pathway, PTP1B activity inhibition or acting as partial PPARγ agonists. These phytocompounds were isolated from 91 plants, belonging to 57 families and triterpenoids are the most sous-class of secondary metabolites showing this activity. Among all the phytocompounds listed in the current review, only 14 biomolecules have shown an interesting activity against diabetes and its complications in clinical studies.

Conclusion:

Epicatechin, catechin, epigallocatechin 3-gallate, quercetin, quercetin 3-glucoside, berberine, rutin, linoleic acid, oleanolic acid, oleic acid, chlorogenic acid, gallic acid, hesperidin, and corosolic acid are promising phytocompounds that showed great activity against diabetes and diabetes complications in vitro and in vivo. However, for the others phytocompounds further experimental studies followed by clinical trials are needed. Finally, foods rich in these compounds cited in this review present a healthy diet for diabetic patients.
A Soil Mechanical Model for Deformable Grounds Under the Dynamic Action
of High-Mobility Tracked Vehicles
Authors: Li Qiang , Liu Xintian
Published: May 2022

Background:

The mechanical properties of the soil are key factors for studying the
ground adhesion capability of high-speed tracked vehicles under the action of dynamic loads. Classic
mechanical models of ground surface soil are insufficient to predict the mobility of high-speed
tracked vehicles.

Objectives:

The aim was to study a soil mechanical model for deformable grounds under the dynamic
action of high-mobility tracked vehicles.

Methods:

According to the high loading and shear rate of high-speed heavy-duty tracked vehicles, a
three-dimensional soil simulation model for deformable grounds was established. Numerical calculations
were performed.

Results:

The correctness of the simulation model was validated through the comparison of the numercal
calculation results with the soil-bin test results.

Conclusion:

On the basis of the empirical pressure-sinkage and the Janosi shear model of ground
surface soil, and coupled with factors such as the loading and shear rate, a new improved mechanical
model of ground surface soil was built for the running conditions of high-speed heavy-duty tracked
vehicles. The correctness of the improved model was validated through the comparison of the calculation
results of the improved model with the numerical simulation results, which provides a basis for
studying the driving performance of high-speed heavy-duty tracked vehicles on deformable grounds.
Recent Evidence-based Treatments for COVID-19: A Review
Authors: Ali Faraat , Anjum Varisha , Chauhan Garima , Ali Asad , Ahamad Javed
Published: May 2022

Corona virus disease (COVID-19) is a pandemic disease caused by SARS-COV2 that attacks primarily the respiratory system of the host. This disease was first reported in early December 2019, and the World Health Organization (WHO) classified the ongoing COVID-19 outbreak as a pandemic disease causing global public health emergency by mid-January 2020. It is the human-to-human transmission that occurs by droplets, infected hands or surfaces with an incubation time of 2-14 days. It displays signs and symptoms, and if the disease progresses it leads to death. To avoid symptomatic symptoms or increase infection severity, early diagnosis, quarantine, and supportive care can help to cure the patient infected with COVID-19. Several attempts have been projected for the development of vaccines against COVID-19. As of July 2, 2021, 600 vaccine candidates worldwide were evaluated against SARS-CoV-2, in which 300 have reached out to the preclinical stage of their development. Presently, Moderna (mRNA-1273), Shenzhen Geno-Immune Medical Institute (LV-SMENP-DC), Shenzhen Geno-Immune Medical Institute (Pathogenspecific aAPC), CanSino Biologicals (Ad5-nCoV), Inovio Pharmaceuticals (INO-4800) have plunged into the phase I/II clinical trials (Source: ClinicalTrials.gov website; WHO). Scientists are increasingly seeking a key hide behind pathogenic pathways and epidemiological features, as well as future drug goals, which will lead to the development of successful strategies for prevention and treatment. Based on the current published data, we summarize the structure, life cycle of SARS-CoV2 and the various product categories available as anti-COVID-19 agents (antiviral), with special emphasis on Chinese herbal medicines, which were licensed as anti-COVID agent by the Chinese Government. Such knowledge can be used as guidelines for COVID-19 clinical therapy.
WITHDRAWN: Effect of a Unani Formulation in Sayalan al-Rahim (Abnormal
Vaginal Discharge)- A Clinical Study
Authors: Basri Rabia , Begum Wajeeha , Ansari Zakir
Published: May 2022

Since the authors are not responding to the editor’s requests to fulfill the editorial requirement, therefore, the article has been
withdrawn.

Bentham Science apologizes to the readers of the journal for any inconvenience this may have caused.

The Bentham Editorial Policy on Article Withdrawal can be found at https://benthamscience.com/editorial-policies-main.php

Bentham Science Disclaimer:

It is a condition of publication that manuscripts submitted to this journal have not been published and will not be simultaneously
submitted or published elsewhere. Furthermore, any data, illustration, structure or table that has been published elsewhere
must be reported, and copyright permission for reproduction must be obtained. Plagiarism is strictly forbidden, and by submitting
the article for publication the authors agree that the publishers have the legal right to take appropriate action against the
authors, if plagiarism or fabricated information is discovered. By submitting a manuscript, the authors agree that the copyright
of their article is transferred to the publishers if and when the article is accepted for publication.
A Review on Some Indian Medicinal Plants useful in Hair Care
Authors: Bhargavi Manju N. , Devang Pandya J.
Published: May 2022

Hair related problems are an ever-increasing problem. Compared with chemical herbal ingredients are more preferred because of their easy availability and lesser side effects. The utilization of novel medicinal plant ingredients in various formulations such as hair tonic, hair gels, hair oils and hair dyes has proved to be beneficial than the formulations containing chemical components. These novel ingredients have helped in the enhancement of the beauty of hair and help in the treatment of various hair problems such as dandruff, alopecia and many more. It is a universal problem affecting both sexes. Herbal cosmetics are now appropriate solution to the current problem. This review describes the use of some natural medicinal plants for hair growth promotion, Anti-hair fall and Anti-grey hair with a brief description of the major use, plant parts used and the active compounds responsible for the use of the herbal plants.
A Candidate for Health Promotion, Disease Prevention and Treatment:
Common Rue (Ruta graveolens L.), an Important Medicinal Plant in Traditional
Medicine
Authors: Shahrajabian Mohamad Hesam
Published: May 2022

Background:

Ruta graveolens L. belongs to Rutaceae; it is a semi-wood perennial or a
small evergreen sub-shrub, which is native to Southern Europe, West Asia and Northern Africa.

Objective:

The goal of this manuscript was to outline the most notable traditional and modern advantages
and pharmaceutical benefits of common rue.

Methods:

The manuscript covers review articles, randomized control experiments, analytical studies
and observations, which have been gathered from different sources, such as Google Scholar, Scopus,
Science Direct and PubMed. A review of the literature was carried out using the keywords rutin, Ruta
graveolens L., rue, common rune, coumarin, natural products and pharmaceutical benefits.

Results:

Rue contains quinoline alkaloids, such as graveoline and graveolinine, acridone alkaloids,
such as furacridone and gravacridone, furanoquinoline dictamnine, coumarins, such as gravelliferone,
isorutarin, rutacultin, rutaretin, and suberenone, and the furanocoumarins 5-methoxypsoralen (bergapten)
and 8-methoxypsoralen (xanthotoxine). Most of its aromatic and medicinal properties are due to
the presence of rutin and its essential oil. It has been used in folk medicine as a stimulant, for its antiinflammatory
and analgesic properties, anti-androgenic activity, anti-hyperglycemic effects, antihyperlipidemic
effects, xanthine oxidase inhibition activity, and anticancer properties.

Conclusion:

According to pharmacological and phytochemical advantages, pennyroyal shows its importance
as a medicinal plant in both modern medicinal science and traditional medicine.
The used of deixis in “World Travel Magazine”
Authors: Puteri Ni Putu Yumita Arie , Soethama Putu Lirishati , Putra I Komang Sumaryana
Published: May 2022

This research is entitled The Used of Deixis In “World Travel Magazine”. The aims of this research are to identify the types of deixis that used in “World Travel Magazine.” and its reference. The term Deixis comes from classical Greek for one of the most basic things we do with utterances. It means ‘pointing’ via language. The study in this research concerned with the way in which the researcher explains the kinds of deixis and the reference of each deixis which used in the article that published on World Travel Magazine using the theory of Pragmatics focusing on Deixis that purposed by Levinson 1983. Qualitative research was used as the method of the research. The method of collecting the data is documentation. The steps to analyze the data are reading the article, finding the deixis, and classifying the types of deixis.
PERTUMBUHAN POPULASI DAN PERKEMBANGAN Tribolium castaneum (Herbst) (COLEOPTERA: TENEBRIONIDAE) PADA BEBERAPA VARIETAS BERAS
Authors: Wandansari Tyssa Ardhining , Astuti Ludji Pantja , Widjayanti Tita
Published: May 2022

Penelitian ini bertujuan untuk mengkaji pertumbuhan populasi dan perkembangan populasi T. castaneum pada beberapa varietas beras. Penelitian dilaksanakan di Laboratorium Hama Tumbuhan, Departemen Hama dan Penyakit Tumbuhan, Fakultas Pertanian Universitas Brawijaya, Malang. Penelitian ini terdiri dari sepuluh perlakuan dan diulang empat kali untuk pengamatan pertumbuhan populasi dan tiga kali untuk pengamatan perkembangan. Penelitian ini disusun dalam Rancangan Acak Lengkap (RAL). Penelitian dilakukan dengan menginfestasi 15 pasang imago T. castaneum yang berumur 7–14 hari ke dalam tabung yang berisi 30 g beras pakan. Pengamatan perkembangan dilakukan dengan menggunakan 10 butir telur dari imago baru T. castaneum yang dipasangkan pada hari yang sama dan dimasukkan ke dalam tabung fial berisi 3 g pakan beras. Variabel yang diamati pada penelitian ini yaitu mortalitas imago, jumlah telur, larva, pupa, imago baru, fase telur, larva, pupa, dan praoviposisi. Hasil penelitian menunjukkan bahwa varietas beras tidak mempengaruhi pertumbuhan populasi dan perkembangan.