bluuebunny/crossref_metadata_2025 huggingface dataset:
Disturbo Post-Traumatico e comportamento criminale: rischio di recidiva e costrutti personali
Authors: Ardino Vittoria , Di Blasio Paola , Milani Luca
Published: April 2024

Gli eventi traumatici causano esiti psicopatologici di natura diversa e con diverse configurazioni di sintomi. Il presente studio analizza le cognizioni post-traumatiche nei contesti forensi per verificare le connessioni tra esperienze di traumatizzazione precoce, sintomi del Disturbo Post-Traumatico da Stress e rischio di recidiva di reato in una popolazione carceraria. L'ipotesi principale sostiene che cognizioni disfunzionali (worry, percezione negativa del supporto degli altri) mediano la relazione tra i sintomi DPTS ed il rischio di recidiva. Lo studio, inoltre, esplora il modello della Psicologia dei Costrutti Personali basato sulla teoria di Kelly (1995) per comprendere in che modo un sistema di credenze post-traumatico possa frammentare la visione del mondo e del Sé del campione. I risultati hanno mostrato che la percezione negativa del supporto degli altri media tra sintomi DPTS e rischio di recidiva e che i partecipanti con i sintomi DPTS hanno maggiori difficoltà ad integrare eventi traumatici e il reato stesso all'interno del loro sistema di costrutti e credenze.
Coparenting, parent-adolescent conflict and internalizing symptoms in Brazilian adolescents
Authors: Pereira Mosmann Clarisse , Rodrigues Machado Mariana , Lima Melina , Rodrigo Schaefer Jeferson , Ochoa de Alda Martínez de Apellaniz Iñigo
Published: April 2024

Coparenting might impact on child development, on the intensity of parent-child con-flict, and on the manifestation of internalizing symptoms. Children's perception of coparenting and gender specificities are important to understand this phenomenon. The direct relationship mediated by the intensity of the parent-adolescent conflict in symptom manifestation and the effects of the moderation of the adolescent's gender were investigated. The study included 357 adolescents, 53.2% female, aged 11 to 18 years (M = 14.42; SD = 1.84). The results indicated that the relationship between coparenting and the internalizing symptoms presented by the adolescents are mediated by the intensity of parent-adolescent conflicts. The findings contribute to the identifi-cation of the coparenting reflexes and direct clinical strategies to adolescents and fam-ilies.
Українська мова у ЗМІ. 1 та 2 частина : навч.-метод. посіб. для здобувачів першого (бакалавр.) рівня вищої освіти галузі знань 06 «Журналістика», спец. 061 «Журналістика». [Електронне видання]
Authors:   Національний університет ", Назаренко Оксана Миколаївна ,   Одеська юридична академія"
Published: April 2024

Навчально-методичний посібник складається зі вступу, структури навчальної дисципліни, тематичного плану, теоретичного матеріалу для лекцій, планів і завдань до практичних занять, тем і завдань для самостійної роботи, питань до іспиту та методичних вказівок для викладачів, які проводять практичні заняття. Навчально-методичний посібник підготовлено відповідно до освітньої програми вищої освіти за спеціальністю 061 «Журналістика» і рекомендовано використовувати у навчальній роботі при підготовці фахівців за першим (бакалаврським) рівнем вищої освіти.
Young Residents’ Perceptions of Windhoek’s Streetscapes
Authors: Roland Stephanie , Stevens Quentin , Simon Katrina
Published: April 2024

Urban streets are public spaces that can gather residents and create vibrant and diverse experiences contributing to the positive qualities of an urban landscape. Windhoek’s suburban model, which has evolved from colonial and apartheid planning, relies heavily on private motorcars, which most residents cannot afford. The city’s various neighbourhoods have historically been segregated by race, ethnic group, and wealth. The city lacks public spaces where different residents can easily and freely interact. Windhoek presents a particularly unsettling disconnect between the formal systems governing and producing the city and residents' socio-cultural backgrounds and everyday spatial practices. Windhoek presents a particularly unsettling disconnect between the formal systems governing and producing the city and residents' socio-cultural backgrounds and everyday spatial practices. This paper develops a methodology that combines non-expert participatory methods and tools to investigate perceptions of young residents of Windhoek’s streetscape, extending beyond objective spatial descriptions and generalised socio-political critiques to address individual subjective perceptions, recollections, and experiences of specific urban spaces within Windhoek. The conceptual lens of the uncanny is employed as an organising concept to consider how the spatial and social legacies of colonialism and apartheid continue to affect Windhoek residents’ perceptions and behaviours in publicly-accessible spaces. The paper examines residents’ objective topological understandings of the city’s spatial structure, their movement through it, and their subjective, qualitative social perceptions about place, value and belonging connected to that spatial understanding.
Between Alienation and Revolution
Authors: Almeida Rachel de Castro , Knierbein Sabine
Published: April 2024

Following the tracks of the soiree collectives in the metropolitan area of Belo Horizonte, this article aims at analysing the role of the dimension of everyday life, which according to Lefebvre means the constant movement between the tendency to repeat and the capacity for social transformation, the constant movement between routine and invention. These collectives are formed by young people, most of them residents of peripheral areas who have revealed themselves to be holders of a new subjectivity capable of explaining their place in the world and justifying their existence drawing from the pride of being peripheral, which results in a new way of political action. The daily life lived, perceived, and conceived in the context of their social and symbolic place occupied by the peripheries and their social actors has been reframed in the face of a set of social transformations and, consequently, it produces new public spheres and new ways of expression of emancipatory struggles. The ethnography carried out seeks to apprehend the intertwining of poetry, performance, and the occupation of public space. The critique of everyday life reveals those patterns of behaviour, organization strategies of groups and subgroups, networks of relationships and networks of meanings, as well as systems of material and symbolic exchanges. Indeed, such collectives are expressions of everyday resistance, manifested in poetry, in bodily expressions, in the way activities are organized and performed. In these soirees, critical and political reflections are collectively created, making the creative and liberating capacity emerge.
Prevalence of Colistin Pan Resistance among Multidrug-Resistant and Extensively Drug-Resistant Escherichia Coli O157:H7
Authors: Rawaa Jawad  , Zina Alshami  , Haidar Jiham
Published: April 2024

Antimicrobial resistance is an important problem threatening human health. With the appearance of colistin-resistant bacteria, the World Health Organization and Centers for Disease Control and Prevention are declaring a global emergency and an alarming disaster that goes back to the time before antibiotics. The usage of colistin rises as a result of the global growth of Enterobacteriaceae, which produces carbapenemase and certainly causes the emergence of resistance to investigate the prevalence of colistin resistance among multidrug-resistant and extensively drug-resistant E. coli. The cross-sectional study included 140 swab samples and 200 urine samples that were collected from patients attending Al Imam Al Hussein Medical City in Karbala. The identification of bacterial isolates and the pattern of antibiotic resistance were determined using the fully automated VITEK 2 compact system in addition to the manual antibiotic resistance testing confirmation. The isolates were highly resistant to Ticarcillin (94.4%), Trimethoprim/ Sulfamethoxazole (91.1%) and Piperacillin (87.3%). In contrast, colistin had the lowest (4.2%) out of the total multi-drug resistant (MDR) strains that formed (46.4%) and the extensively-drug resistant (XDR) strains (25.4). Antimicrobial resistance is one of the biggest health problems facing people today. In Iraq, the appearance of colistin resistance (2.8%) among extensively drug-resistant Escherichia coli O157:H7 may lead to failure of treatment, especially among burn and UTI patients. It is urgently recommended to lower the occurrence of antibiotic resistance through cautious antibiotic usage and stringent infection control protocols, which are priorities.
Phytochemicals, Mineral Elements and Antioxidants Evaluation of Some Commonly Consumed Desert Fruits
Authors: Danzomo Ibrahim Muhammed , Yunusa Abdulmumin , Adamu Abdu Umar , Danjaji Hauwa Ibrahim , Dalhatu Maimuna Muhammad , Usman Ibrahim Muhammad , Lawan Umma
Published: April 2024

The medicinal properties of fruits are closely related to their available phytochemicals, as well as antioxidant capacity. Many of the indigenous fruits have been traditionally used as folk medicine. This study aims to evaluate the phytochemicals, mineral elements, and antioxidant properties of five (5) commonly consumed desert fruits such as Hyphaene thebaica, Detarium senegalensce, Ziziphus jujuba, Dialium guineense and Diospyros mespiliformis. The phytochemicals, mineral elements, and antioxidants were carried out using standard methods of analysis. The result revealed that phytochemicals such as alkaloids, flavonoids, phenols, tannins, saponins, steroids, terpenoids, and glycosides were present in all five fruits studied with varied compositions. While the mineral elements such as Potassium (K), Magnesium (Mg), Calcium (Ca), Sodium (Na), Iron (Fe), Manganese (Mn), Zinc (Zn), and Copper (Cu) were present indicated that the fruits have substantial mineral elements, however, varied according to the fruits species studied, Hyphaene thebaica exhibits the highest elemental content. The DPPH inhibition properties emphasize the diverse antioxidant capabilities of the studied fruits in which Diospyrosme spiliformis (DS) emerges as a standout in DPPH inhibition activity, exhibiting robust antioxidant activity, closely followed by Dialium guineense (DG). The nitric oxide radical scavenging reveals a concentration-dependent response in the NO radicals scavenging activity for all the fruits and ascorbic acid. The findings conclude that the five desert fruits species revealed different phyto-constituents, mineral elements, Nitric oxide radical scavenging effect, and DPPH inhibition properties suggesting potential medicinal and nutritional properties of the five desert fruits.
Antibacterial Effect of Pleurotus ostreatus on Selected Bacterial Isolates
Authors: Oda Onoja , Muhammed Aisha
Published: April 2024

Pleurotus ostreatus, commonly known as oyster mushrooms, are edible fungi with a long history of culinary and medicinal use. This study was carried out to determine the anti-bacterial effect of Pleurotus ostreatus against Escherichia coli, Salmonella typhi, and Staphylococcus aureus. The bacterial isolates were collected from the Microbiology Laboratory of Caleb University, Lagos, Nigeria. The isolates were confirmed using biochemical tests. The antibacterial susceptibility pattern of the isolates to different antibiotics was determined using the disc diffusion technique. Extraction was carried out on dried and finely ground Pleurotus ostreatus using methanol and water as solvents. Susceptibility of the isolates to Pleurotus ostreatus was done using the agar well diffusion technique. The disc diffusion technique showed susceptibility and resistance of the bacterial isolates to different antibiotics. Methanol extracts of Pleurotus ostreatus showed higher anti-bacterial activity against the selected bacteria judging by the longer diameter of zones of inhibition. More studies should be carried out on Pleurotus ostreatus to extract and purify the individual bioactive components which could form the basis for the development of antimicrobial agents.
Comparative Analysis of Proximate Composition of Rotten Banana (Musa sapientum) and Pineapple (Ananas comosus)
Authors: Muhammad Ahmad , Musa Daniel Danladi , Kutawa Abdulaziz Bishir
Published: April 2024

This study was aimed at determining the proximate composition of rotten banana (Musa sapientum) and pineapple (Ananas comosus). Rotten banana (Musa sapientum) and pineapple(Ananas comosus were purchased from Kofar Yandaka Junction and Katsina State Transport Authority (KTSTA) roundabout and transported directly to the soil and water laboratory, Geography department of Umaru Musa Yar’adua University Katsina. The Proximate analysis was carried out using a standard protocol. The proximate compositions analyzed were moisture content, ash content, crude fat, crude protein, crude fiber, and carbohydrates. Results showed variation among the tested parameters with moisture contents ranging from 14.37%-25.99% in pineapple and banana, ash content 4.37%-4.39% in pineapple and banana, crude fat 24.96%-56.30% in banana and pineapple, crude fiber 0.83%-0.39% in pineapple and banana, crude protein 10.63%-19.38% in pineapple and banana and finally carbohydrates with a range of 13.50%-24.89% in pineapple and banana respectively. It showed there is no significant difference between the proximate compositions of the two fruit samples (P- value = 0.07345, Fcrit =4.387, F-Value =3.642, P ≤ 0.05). It was also concluded that the presence of high amounts of nutrients in the tested samples makes it a good candidate for energy and food supplements for both humans and animals as it is needed for cell growth and proliferation. Finally, it was recommended that further research should be conducted on both the fresh, rotten, and dried to explore the differences between them for optimum utilization of their nutritional compositions.
Land Cover Modelling with Sentinel 2 in Water Balance Calculations of Urban Sites
Authors: Guizani Douraied , Buday-Bódi Erika , Tamás János , Nagy Attila
Published: April 2024

This study investigates how a land cover map is produced using Sentinel 2 satellite images and how the resulting map is integrated with the calculation of hydrological parameters. Due to its capacity to deliver high-resolution spatial data, satellite imagery is increasingly being used for land cover mapping (1). The process involves several stages, including pre-processing of the Sentinel 2 imagery, image classification using machine learning algorithms, and post-processing of the classified image to generate a land cover map. The resulting land cover map is then integrated with hydrological parameters such as precipitation, evapotranspiration, and soil characteristics to calculate various hydrological parameters.  Debrecen, north-east Hungary is the study area. This study's method is suitable for usage in other cities. Understanding the relationship between land cover and water availability requires the integration of the land cover map with hydrological parameters (2). The study demonstrates the potential of using remote sensing data for hydrological studies and highlights the importance of integrating various data sources for accurate estimation of hydrological parameters. The results show that the land cover classes have a significant impact on the water balance of urban sites. This study outlines the key steps involved in creating a land cover map using Sentinel 2 satellite imagery and integrating it with hydrological parameters calculation. The application of this strategy supports sustainable water management techniques and offers insightful information about a region's hydrological processes.
Deworming the Grinder for Successful Extrication of a Mangled Hand: A Case Report
Authors: Md Yusoff Zuhri , Harun Mohd Hezery , Ab Halim Ashraf Hakim , Mohamed Ramlee Fadzrul Abbas , Lim Teck Siang
Published: April 2024

Grinding machine injuries are known to cause severe mutilating injuries of the upper limb. In some cases, the machinery equipment may still be attached to the limb when the patient reaches the hospital. In treating these injuries, the patient’s hemodynamic status should be the first priority of resuscitation. Following this and whenever possible, a reversal of the grinding mechanism should be done to free the limb. This would allow assessment of the extent of zone-of-injury prior to starting the surgical procedure. We report a case of a 28-year-old male who sustained a mangled hand injury that was successfully extricated from an industrial grinding machine, thereby allowing preservation of precious length of the limb during surgery. This case highlights the importance of adhering to safety precautions at the workplace to reduce the risk of potential occupational hazards when dealing with machinery equipment.
Morphometric Study of Posterior Aspect of Distal End of Human Adult Dry Left Humerus
Authors: Ara Jubaida Gulshan , Naushaba Humaira , Hossain Khan Khalid Mosharof , Begum Tahmina , Khan Laila Farzana , Mohammad Kabir Abul Kalam
Published: April 2024

Context: Humerus is the long bone of upper limb. The aim of this study is to find out valuable normative data of posterior aspect of distal end of human adult dry left humerus that can enrich the anatomists and play an important role to anthropological researchers and forensic experts. It is also important for orthopedic surgeons in surgical reconstruction of distal humeral fracture and correction of congenital and traumatic anomalies.

Materials and Methods: A cross sectional analytic type of study was conducted in the department of Anatomy of Sir Salimullah Medical College, Dhaka from July 2011 to Dec 2012. Two hundred left sided humerus were collected from the students of Department of Anatomy of Sir Salimullah Medical College, Dhaka and Dhaka National Medical College, Dhaka. Measurements were taken from posterior aspect of distal end of left humerus by direct physical standard osteometric method and recorded in the metric unit centimeter (cm).

Result: The result revealed that the male values were higher than female. The measurements were statistically analysed. There were significant difference (p=0.001) between male and female values.

Bangladesh J. Anat. 2015; 13(1) : 11-15
Phân tích thực trạng an ninh năng lượng tại Việt Nam sử dụng chỉ số ESI và mô hình RCA
Authors: Nguyễn Thị Ánh Tuyết , Phạm Thị Hồng Điệp
Published: April 2024

Đảm bảo an ninh năng lượng và phát triển bền vững chiếm một vị trí quan trọng trong chiến lược phát triển kinh tế, công tác chính trị, ngoại giao của các quốc gia. Thời gian qua chính phủ các quốc gia đã chú ý xây dựng các chiến lược nhằm đảm bảo an ninh năng lượng, hướng tới phát triển xanh và bền vững. Kéo theo đó là sự gia tăng về yêu cầu nghiên cứu các vấn đề an ninh năng lượng nhằm đánh giá, tìm kiếm giải pháp, xác định mục tiêu để đảm bảo an ninh năng lượng quốc gia. Bài viết này phân tích thực trạng an ninh năng lượng tại Việt Nam giai đoạn 2000-2022 thông qua việc xây dựng bộ chỉ số đo lường an ninh năng lượng (ESI). Hơn nữa, bài viết đề xuất mô hình RCA (Root-Cause Analysis) để phân tích nguyên nhân dẫn tới thực trạng an ninh năng lượng, từ đó khuyến nghị các giải pháp cụ thể nhằm nâng cao an ninh năng lượng tại Việt Nam. Kết quả đã chỉ ra rằng Việt Nam đang bị giảm mức độ an ninh năng lượng so với giai đoạn 2010-2015, và chuyển từ một quốc gia độc lập về năng lượng thành quốc gia phụ thuộc vào năng lượng.
Rủi ro địa chính trị và sự đa dạng hóa thu nhập của ngân hàng thương mại
Authors: Nguyễn Thành Công
Published: April 2024

Sử dụng dữ liệu từ 2.399 ngân hàng thương mại tại 42 quốc gia trong giai đoạn 2006–2021, nghiên cứu này phát hiện ra rằng sự gia tăng rủi ro địa chính trị làm giảm mức độ đa dạng hóa thu nhập của ngân hàng thương mại, phản ánh rằng ngân hàng có xu hướng thu hẹp các hoạt động kinh doanh ngoài lãi trong giai đoạn rủi ro địa chính trị tăng cao. Thu nhập từ phí dịch vụ và hoa hồng ít chịu ảnh hưởng tiêu cực từ rủi ro địa chính trị hơn so với thu nhập từ việc mua bán tài sản tài chính và hàng hóa. Các ngân hàng nhỏ với mô hình kinh doanh tập trung vào hoạt động cho vay truyền thống nên ít chịu ảnh hưởng tiêu cực trên khía cạnh thu nhập ngoài lãi hơn so với các ngân hàng lớn khi rủi ro địa chính trị tăng lên.
MARKETING CONTENT INSTAGRAM SEBAGAI MEDIA PROMOSI PADA PT POS INDONESIA (PERSERO) KCU MAKASSAR 90000
Authors: Setianingsih Ayu , Murtafia Murtafia
Published: April 2024

Penelitian ini bertujuan untuk membuatkan marketing content berupa video promosi menggunakan alur cerita drama yang digunakan sebagai strategi promosi pada KCU Pos Makassar 90000. Metode penelitian yang digunakan dalam penelitian ini adalah deskriptif kualitatif. Pendekatan deskriptif kualitatif ini menggunakan pengambilan dan pengumpulan data melalui telaah dokumen dan wawancara semi terstruktur dengan mengajukan pertanyaan-pertanyaan kepada beberapa pihak terkait yang dapat membantu peneliti dalam proses penelitian.  Hasil penelitian ini menunjukkan indikator promosi penjualan yang digunakan yaitu media promosi, waktu promosi, frekuensi promosi, kualitas promosi, kuantitas promosi, dan ketetapan atau kesesuaian sasaran promosi. Selain itu, juga menggunakan elemen-elemen marketing content sehingga dapat dikatakan handal yaitu relevance, informative, reliability, value, uniqueness, emotions, dan intelligence.  Sehingga output dari penelitian ini adalah marketing content berupa video menggunakan alur cerita drama yang digunakan sebagai media promosi yang di posting pada akun Instagram KCU Pos Makassar 90000. Marketing content berupa video menggunakan alur cerita drama diharapkan mampu menjadi media promosi yang baik guna memperkenalkan produk dan jasa layanan pada KCU Pos Makassar 90000 dan dapat menjadi referensi konten bagi perusahaan.
PENINGKATAN KUALITAS PELAYANAN MELALUI SURVEI KEPUASAN MASYARAKAT DI PUSKESMAS PARANGLOE
Authors: Irman Arif Aprilia Jaya Ganda , Fitri Azmi Ilima
Published: April 2024

Pelayanan publik sebagai pemberian layanan kepada masyarakat luas merupakan tuntutan besar yang wajib dipenuhi oleh seluruh negara termasuk Indonesia. Pelayanan publik tidak hanya hadir dan diterapkan tanpa diikuti dengan peningkatan kualitas. Dibutuhkan respon baik dari masyarakat terhadap pelayanan tersebut untuk dapat dikategorikan sebagai pelayanan prima. Penyediaan fasilitas pelayanan kesehatan juga merupakan salah satu bentuk pelayanan publik yang bisa diberikan pemerintah. Salah satu instansi pemberian pelayanan kesehatan di Indonesia yang banyak dijumpai yaitu Puskesmas. Puskesmas Parangloe merupakan salah satu instansi yang menyediakan fasilitas pelayanan kesehatan. Penelitian ini menggunakan mixed method demi tercapainya hasil yang lebih lengkap atau komprehensif. Berdasarkan hasil penelitian terhadap sembilan unsur pelayanan yang diberikan, Puskesmas Parangloe memperoleh nilai IKM sebesar 76,25 atau dalam kategori BAIK. Namun demikian, masih terdapat unsur dengan nilai pelayanan yang buruk sehingga Puskesmas Parangloe perlu melakukan berbaikan dan peningkatan terhadap pelayanan kesehatan demi tercapainya kepuasan masyarakat.
Subcuticular and biofilm microbiomes in Holothuria tubulosa and their potential for denitrification
Authors: Martínez-Moreno S , Leon-Palmero E , Pula HJ , Cabello AM , Ferrera I , Reche I
Published: April 2024

Holothurians, as benthic invertebrates inhabiting marine ecosystems, have a crucial function in that they actively process organic detritus in the sediments. Previous works have provided evidence of the capability of holothurians to reduce nitrate and ammonium concentrations in aquaculture tanks. However, the mechanisms underlying this nitrogen decrease still need to be elucidated and might be related to bacterial symbionts in the holothurians. Here we characterize the community of bacterial symbionts in the biofilm and subcuticle of Holothuria tubulosa and explore the presence of nitrification and denitrification genes. To characterize these bacterial symbionts, we extracted DNA and amplified the V3-V4 hypervariable region of the 16S rRNA gene. We obtained a notable contribution of Bacteroidota, Alphaproteobacteria (mostly Rhodobacterales), and Gammaproteobacteria (mostly Pseudomonadales) both within the biofilm and subcuticle of H. tubulosa. Subsequently, we tested the presence of specific genes encoding enzymes involved in nitrification (i.e. archaeal amoA and bacterial amoA) and denitrification (i.e. nirS and nosZ). Our results confirm the presence of denitrification genes in the holothurian biofilms. These findings indicate that the holothurians house a diverse community of bacterial symbionts, which includes species with the potential for nitrogen removal. Therefore, holothurian holobionts may play a multifaceted ecological role, both processing organic detritus and reducing nitrogen levels in coastal areas. These roles could be extended to sustainable aquaculture, making them valuable ecosystem engineers with significant implications for ecosystem and aquaculture health.
Interaction of Threonine with Biometal Chlorides in an Aqueous Environment at 25°C
Authors: Bektasheva U. , Altybaeva D. , Abdullaeva Zh. , Mataipova A.
Published: April 2024

The method for the synthesis of complexes with transition group biometal salts with the amino acid threonine includes improvement of reaction conditions, selection of reagents and analytical methods to confirm the formation of complexes. Research purpose: obtaining complex compounds of biometals, cobalt chloride, nickel chloride and manganese chloride with the amino acid threonine, as well as the study of their physicochemical and biological properties. In the synthesis of complex compounds, the preparative method was used. Compositions of the formed crystals were analyzed by IR spectroscopy. The structure and shape of cobalt, nickel and manganese crystals were determined using a microscope. The identity of the obtained compounds was confirmed by IR spectroscopy and microscopic analyses. We can conclude that threonine in the complex is coordinated to metal ions through the oxygen atoms of the carboxyl and nitrogen groups of the amine groups.
Study of Populations of Urtica dioica L. in the Mountain Areas of Nakhchivan Autonomous Republic
Authors: Mammadli T. , Ganbarov D.
Published: April 2024

The distribution, ontogenetic structure, age and growth structure of hay meadow populations, productivity in different periods of ontogenesis of all populations of Urtica dioica L. are considered. Populations of this species are identified and studied. Urtica dioica is a common plant in the highlands of the Nakhchivan Autonomous Republic. An assessment of 10 populations was carried out, the data were presented in the form of tables and graphs. The structure of ontogenesis was studied based on the population method. It has been established that this plant is distributed as part of plant groups in the herbaceous, shrub and forest vegetation of the Sharur, Babek, Kengerli, Shahbuz and Ordubad administrative regions of the Nakhchivan Autonomous Republic.
Taxonomy of the VeronicaL. Genus in the North of the Lesser Caucasus
Authors: Abbasova L.
Published: April 2024

The territory of Azerbaijan is distinguished by a wide variety of vegetation. Most of the 5,000 plant species described in Azerbaijan grow in the north of the Lesser Caucasus. The composition of the Veronica L. genus, Plantaginaceae family has been studied. During the work, 21 species, 2 subspecies were identified. There are 200 species of this genus throughout the world, 53 in the Caucasus, and 40 in Azerbaijan. The work provides a systematic annotated list of all identified species of the Veronica genus.
Transport Pollution Impact Assessment on the Platanus orientalis L. Physiological Properties
Authors: Mammadova R.
Published: April 2024

The influence of vehicle pollution on the physiological properties of the woody plant Oriental plane tree (Platanus orientalis L.) in the conditions of the city of Baku (Azerbaijan) is considered. To assess the physiological state of plants, a comparative analysis of indicators of delayed chlorophyll a fluorescence of leaves of trees growing in areas located at different distances from the highway was carried out. The pattern of changes in the various phases of the induction curve of the millisecond component of the delayed fluorescence of chlorophyll a was used to assess the state of photosystem II. The results of the study showed that both the donor side of photosystem II and the acceptor side exhibit a fairly high sensitivity to vehicle pollution. As a result, the efficiency of the photosynthesis process deteriorates under polluted conditions. This makes it possible to use P. orientalis as an indicator plant to assess environmental quality.
Fish Development in Lake Ecosystems, Effect of Heavy Metals
Authors: Karimova Sh.
Published: April 2024

Heavy metals enter the water bodies and combine with the water buffer system, then turn into poorly soluble hydroxides, carbonates, sulfides and phosphates, and also form metal-organic complexes, accumulate in the bottom sediments and in general in the bodies of the fish fauna of the reservoirs of the area, seriously affecting their development. It was determined that the amount of Ca2+ ions varied from 17 mg/l to 112 mg/l, and the amount of Mg2+ ions from 5.5 mg/l to 83.5 mg/l, in other words, towards autumn. water hardness has increased. The amount of alkali metal (Na+ + K+) ions is much lower in spring than in summer and autumn. According to the cations, the amount of chloride and sulfate ions increases in autumn. Thus, the impact of anthropogenic factors on fish is diverse and manifests itself primarily in morphological anomalies and changes in the basic biological parameters of fish populations. The main of them is the reduction of productivity and the complete loss of their natural forms, the increase of individuals and the increase of mortality.
Intestinal Coccidia (Eimeriidae, Coccidia) of Synanthrophic Animals of the Urban Population
Authors: Gurbanova T. , Gaibova H. , Isgenderoa N.
Published: April 2024

Intracellular parasitic protozoa (Protozoa) have been found in many vertebrates inhabiting various natural regions of the Earth. Numerous parasitic protozoa have been found in vertebrates in Azerbaijan, including representatives of the eimeriid coccidia (Eimeriorina: Coccidia: Apicomplexa, Protozoa). Among them, representatives of the genera Cryptosporidium(zoonoses) and Eimeria (highly specific) have the greatest practical significance in animal husbandry and medicine. Synanthropes, especially inhabitants of the urbanized ecosystem, are in contact with domestic animals and humans, which contributes to the exchange of ecto- and endoparasites between them. The article presents the results of studies of coccidia infection of synanthropic animals in Baku and its environs. And an attempt was made to find out whether wild animals are reservoirs of opportunistic pathogens. The research material was oocysts of eimeriid coccidia found in the faeces of synanthropic animals. Fecal samples of the studied animals were collected in their habitats. A total of 286 fecal samples from 6 species of animals were examined: 72 birds (12 European herring gulls and 60 rock doves), 161 rodents (54 brown rats and 107 house mice), domestic dogs and cats — 25 and 28, respectively. All studied animals were infected with cryptosporidium. Eimeria oocysts were found only in rodents and one rock dove. Based on morphometric parameters, it can be argued that the cryptosporidium oocysts found in mammals are C. parvum-like and C. muris-like, in rock doves C. parvum-like, C. galli-like. Single cryptosporidium oocysts found in gulls were not diagnosed. Eimeria oocysts found from rats match E. miyairii in morphometric characteristics, and two different types of Eimeria oocysts — Eimeria sp. 1 and Eimeria sp. 2 are supposed to be new species. Eimeria oocysts found by us in mice correspond in their size and morphology to E. krijgsmanni.
The Species Composition and Prevalence of Thorny-Headed Worms (Acanthocephala: Echinorhynchidae, Neoechinorhynchidae and Pomphorhynchidae) in Trouts, Complex Measures to Control Them in Fish Farms in the Territory of Azerbaijan Republic
Authors: Suleymanova A.
Published: April 2024

During period 2015-2020 spreading of acanthocephaliasis in the rainbow and brown trout in the fish breeding farms of Azerbaijan Republic was studied. Totally, from 668 fish examined specimens 430 (64.37%) were infected. Correlation of data on the extensiveness and intensity of invasion by thorny-headed worms (Acanthocephala) in trout farms is ventured to make an assumption about unfavorable epidemiological situation in trout breeding farms of the Republic of Azerbaijan. For the purpose of control acanthocephaliasis in trout, a number of drugs were used. The most effective drug was Tetramizole-20%, which was adopted in the trout farms.
Regularities of Growth and Development of Buffaloes
Authors: Ibragimov A. , Maharramov M.
Published: April 2024

Based on the research, an analysis of the biological characteristics of the growth and development of buffaloes in certain periods and stages was carried out. The growth rate of animals of all ages depends on feeding conditions, time of year and other environmental factors. The stage of onset of sexual activity in animals differs sharply from all periods of growth and development. It has been revealed that timely mating of animals, on the contrary, naturally lengthens the maturation period and makes it possible to breed larger animals and obtain greater productivity in the future. For normal processes of growth and development in the body of animals, it is necessary to improve the external environmental conditions and, above all, the conditions of feeding, housing and care. It is necessary to build a breeding business in an exemplary manner and thus increase the weight and milk and meat productivity of livestock.
‘Text Corruptions’ Corruption: Restoring C.S. Lewis's Critical Satire
Authors: Ricke Joe
Published: April 2024

This essay examines in detail a C.S. Lewis letter, published in The Times Literary Supplement that was, in fact, an example of ‘mock-criticism’ (as in ‘mock-epic’), being a satiric parody of an argument made by eminent Shakespeare scholar John Dover Wilson. Lewis published his ‘minor disagreement’ in March 1950, to which Dover Wilson responded with appreciation for Lewis's good humour but continued disagreement on the point of contention – that Shakespeare would ever include lines of verse in a section of his prose. By close analysis, the essay demonstrates how the editor of The Collected Letters inadvertently ‘corrupted’ Lewis's original by his formatting and editorial changes. Three versions of the letter are compared to show the specifics of the corruption. Further, Lewis's long critical encounter with Dover Wilson from the late 1920s onward as well as his little-known role as a textual criticism scholar at Oxford are demonstrated to provide the context for interpreting and appreciating the letter. Finally, two other Lewis letters, previously pointed out by Stephanie Derrick (neither published in The Collected Letters) are presented from the Dover Wilson archives as evidence of the cordial scholarly relationship that eventually developed between the two. The essay shows Lewis as a clever, thorough, combative, yet friendly scholar (though perhaps not always all at the same time) engaging in and, in fact, initiating important discussions with perhaps the most significant Shakespearean textual scholar of his time.
Comprehensive evaluation of the aggressive certain degree of the chemical components in water to concrete
Authors: Doan Thy Truc
Published: April 2024

Evaluation and research on the aggressive degree to concrete were done in the previous research. However, the evaluation of aggressive certain degree in water to the concrete was experimented comprehensively in the laboratory by the Viet Nam Standard “TCVN 3994:1985” and ISO 14911:1998. In addition, this paper considers water with the chemical name “Chlorite-Bicarbonate-Sodium-Magnesium” by the Kurlov formula and “TCVN 81:1981”. Especially, comprehensive consideration of chemical analysis that includes Cation (Ca2+; Mg2+; ∑(Fe2+; Fe3+; Na+; K+; and NH4+); Anion (Cl−; SO42−; HCO3−; CO32− and OH−); and the other special items analysis which includes Permanent and Temporary hardness; Alkalinity; CO2 free; CO2 corrosive; Total mineralization; pH value; Nitrite (NO2−); and Nitrate (NO3−). The research results presented “water with chemical characteristics can’t create the aggression in concrete,“ which shows pH concentration is 5 and CO2 corrosion is 20 mg/l (approximately 0.04%); whereas ion Mg2+ is 1.5 g/l (approximately 3%) and SO42− is 0,25 g/l (approximately 0.5%). The total salt content in the presence of an evaporating surface obtains 12,5 g/l (approximately 25%). So research results can be used safely for the design or construction of the reinforcement concrete structures in My Thai Canal Bridge, Rach Gia town, Kien Giang province, Viet Nam, and Construction or Geotechnical as good reference documents in the future.
Anti-inflammatory activity of d-pinitol possibly through inhibiting COX-2 enzyme: in vivo and in silico studies
Authors: Haque Mst. Farjanamul , El-Nashar Heba A. S. , Akbor Md. Showkoth , Alfaifi Mohammed , Bappi Mehedi Hasan , Chowdhury Afsana Kabir , Hossain Muhammad Kamal , El-Shazly Mohamed , Albayouk Tala , Saleh Na’il , Islam Muhammad Torequl
Published: April 2024

Introduction: D-pinitol, a naturally occurring inositol, has diverse biological activities like antioxidant, antimicrobial and anticancer activities. This study aimed to evaluate anti-inflammatory effect of d-pinitol in a chick model. Additionally, in silico studies were performed to evaluate the molecular interactions with cyclooxygenase-2 (COX-2).

Methods: The tested groups received d-pinitol (12.5, 25, and 50 mg/kg) and the standard drugs celecoxib and ketoprofen (42 mg/kg) via oral gavage prior to formalin injection. Then, the number of licks was counted for the first 10 min, and the paw edema diameter was measured at 60, 90, and 120 min.

Results and Discussion: The d-pinitol groups significantly (p < 0.05) reduced the number of paw licks and paw edema diameters, compared to negative control. When d-pinitol was combined with celecoxib, it reduced inflammatory parameters more effectively than the individual groups. The in silico study showed a promising binding capacity of d-pinitol with COX-2. Taken together, d-pinitol exerted anti-inflammatory effects in a dose-dependent manner, possibly through COX-2 interaction pathway.
Integration of the Butina algorithm and ensemble learning strategies for the advancement of a pharmacophore ligand-based model: an in silico investigation of apelin agonists
Authors: Tran Xuan-Truc Dinh , Phan Tieu-Long , To Van-Thinh , Tran Ngoc-Vi Nguyen , Nguyen Nhu-Ngoc Song , Nguyen Dong-Nghi Hoang , Tran Ngoc-Tam Nguyen , Truong Tuyen Ngoc
Published: April 2024

Introduction: 3D pharmacophore models describe the ligand’s chemical interactions in their bioactive conformation. They offer a simple but sophisticated approach to decipher the chemically encoded ligand information, making them a valuable tool in drug design.

Methods: Our research summarized the key studies for applying 3D pharmacophore models in virtual screening for 6,944 compounds of APJ receptor agonists. Recent advances in clustering algorithms and ensemble methods have enabled classical pharmacophore modeling to evolve into more flexible and knowledge-driven techniques. Butina clustering categorizes molecules based on their structural similarity (indicated by the Tanimoto coefficient) to create a structurally diverse training dataset. The learning method combines various individual pharmacophore models into a set of pharmacophore models for pharmacophore space optimization in virtual screening.

Results: This approach was evaluated on Apelin datasets and afforded good screening performance, as proven by Receiver Operating Characteristic (AUC score of 0.994 ± 0.007), enrichment factor of (EF1% of 50.07 ± 0.211), Güner-Henry score of 0.956 ± 0.015, and F-measure of 0.911 ± 0.031.

Discussion: Although one of the high-scoring models achieved statistically superior results in each dataset (AUC of 0.82; an EF1% of 19.466; GH of 0.131 and F1-score of 0.071), the ensemble learning method including voting and stacking method balanced the shortcomings of each model and passed with close performance measures.
The complete genome sequence of unculturable Mycoplasma faucium obtained through clinical metagenomic next-generation sequencing
Authors: Sabat Artur J. , Durfee Tim , Baldwin Schuyler , Akkerboom Viktoria , Voss Andreas , Friedrich Alexander W. , Bathoorn Erik
Published: April 2024

Introduction

Diagnosing Mycoplasma faucium poses challenges, and it's unclear if its rare isolation is due to infrequent occurrence or its fastidious nutritional requirements.

Methods

This study analyzes the complete genome sequence of M. faucium, obtained directly from the pus of a sternum infection in a lung transplant patient using metagenomic sequencing.

Results

Genome analysis revealed limited therapeutic options for the M. faucium infection, primarily susceptibility to tetracyclines. Three classes of mobile genetic elements were identified: two new insertion sequences, a new prophage (phiUMCG-1), and a species-specific variant of a mycoplasma integrative and conjugative element (MICE). Additionally, a Type I Restriction-Modification system was identified, featuring 5’-terminally truncated hsdS pseudogenes with overlapping repeats, indicating the potential for forming alternative hsdS variants through recombination.

Conclusion

This study represents the first-ever acquisition of a complete circularized bacterial genome directly from a patient sample obtained from invasive infection of a primary sterile site using culture-independent, PCR-free clinical metagenomics.
Molecular mechanisms and potential therapeutic targets in the pathogenesis of hypertension in visceral adipose tissue induced by a high-fat diet
Authors: Su Zhenyang , Sun Jin-Yu , Gao Min , Sun Wei , Kong Xiangqing
Published: April 2024

Background

Hypertension (HTN) presents a significant global public health challenge with diverse causative factors. The accumulation of visceral adipose tissue (VAT) due to a high-fat diet (HFD) is an independent risk factor for HTN. While various studies have explored pathogenic mechanisms, a comprehensive understanding of impact of VAT on blood pressure necessitates bioinformatics analysis.

Methods

Datasets GSE214618 and GSE188336 were acquired from the Gene Expression Omnibus and analyzed to identify shared differentially expressed genes between HFD-VAT and HTN-VAT. Gene Ontology enrichment and protein-protein interaction analyses were conducted, leading to the identification of hub genes. We performed molecular validation of hub genes using RT-qPCR, Western-blotting and immunofluorescence staining. Furthermore, immune infiltration analysis using CIBERSORTx was performed.

Results

This study indicated that the predominant characteristic of VAT in HTN was related to energy metabolism. The red functional module was enriched in pathways associated with mitochondrial oxidative respiration and ATP metabolism processes. Spp1, Postn, and Gpnmb in VAT were identified as hub genes on the pathogenic mechanism of HTN. Proteins encoded by these hub genes were closely associated with the target organs-specifically, the resistance artery, aorta, and heart tissue. After treatment with empagliflozin, there was a tendency for Spp1, Postn, and Gpnmb to decrease in VAT. Immune infiltration analysis confirmed that inflammation and immune response may not be the main mechanisms by which visceral adiposity contributes to HTN.

Conclusions

Our study pinpointed the crucial causative factor of HTN in VAT following HFD. Spp1, Postn, and Gpnmb in VAT acted as hub genes that promote elevated blood pressure and can be targets for HTN treatment. These findings contributed to therapeutic strategies and prognostic markers for HTN.
Analysis on the spatiotemporal evolutions of groundwater hydrochemistry and water quality caused by over-extraction and seawater intrusion in eastern coastal China
Authors: Chen Weifan , Wu Chu , Pan Shibing , Shi Long
Published: April 2024

The over-extraction of groundwater has resulted in seawater intrusion and the southward migration of the saltwater interface, gradually deteriorating the groundwater quality in the Weibei Plain. In this research, groundwater samples were gathered from 46 monitoring wells for shallow groundwater during the years 2006, 2011, 2016, and 2021. The hydrochemical features of regional groundwater and the factors influencing the issue were subjected to statistical analysis. Additionally, the assessment of spatiotemporal variations in groundwater quality was conducted using the customized entropy-weighted water quality index (EWQI) method. The relationship between groundwater over-extraction and the southward intrusion of the saltwater interface was compared and analyzed. The results of this paper revealed that the Weibei Plain has been in a state of long-term over-extraction of groundwater from 2000 to 2021, with an average annual over-extraction of 118.49 million m3. The groundwater depression cone areas in the northern part of the study area increased from 3,247.37 to 4,581.34 km2 from 2006 to 2021, with the center of the cone experiencing a drop in groundwater level from −22 to −85 m. The saltwater interface shifted southward by 711.71 km2 from 2006 to 2021. In groundwater, the high concentrations of TH, TDS, and Cl− were primarily related to the seawater intrusion, while higher concentrations of NO3− were mainly determined by frequent agricultural production, industrial wastewater, and domestic sewage discharges. The groundwater hydrochemical types in the study area transitioned from predominantly HCO3·Ca-Mg type in 2006 to HCO3-Na type and SO4·Cl-Ca·Mg type in 2021 due to seawater intrusion. The results of PCA and HCA show the effects of seawater intrusion, human activities, and rock weathering on groundwater hydrochemistry. The evaluation results based on the EWQI revealed that the average value of the samples in 2021 was 101.36, which belonged to Class IV water quality standards, representing the poorest water quality among the 4 years. The southward migration of the saltwater interface led to the deterioration of groundwater quality in the groundwater depression cone areas, which gradually worsened from 2006 to 2021. The maximum increase in EWQI value was 174.68 during the period, shifting from Class III water quality to Class V water quality. Groundwater quality remained relatively better in the western and southern regions which were less affected or unaffected by seawater intrusion. The results of the study can provide a certain reference value for the sustainable management of groundwater resources and the management of groundwater pollution and seawater intrusion in the Weifang City area in the future.