bluuebunny/crossref_metadata_2025 huggingface dataset:
Apresentação
Authors: Ratts Alex , Santana Filho Manoel Martins de
Published: February 2025

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Desafios e perspectivas dos programas de pós-graduação em Geografia no âmbito de sua interiorização
Authors: Rosendo Jussara dos Santos , Miyazaki Vitor Koiti
Published: February 2025

O Programa de Pós-graduação em Geografia do Pontal (PPGEP) iniciou suas atividades em 2015. Está localizado no Campus Pontal, na cidade de Ituiutaba, a cerca de 140 quilômetros da sede da Universidade Federal de Uberlândia (UFU).  Por ter sido criado no contexto da recente expansão e interiorização dos programas de pós-graduação em Geografia no Brasil (2010-2019), em seus oito anos de existência o PPGEP enfrentou uma série de desafios que extrapolam as barreiras institucionais e se correlacionam com as dificuldades vivenciadas, também em termos de Brasil. Mesmo diante de inúmeros desafios, o PPGEP tem alcançado êxito por meio da formação de recursos humanos e contribuições para o desenvolvimento local e regional, principalmente no âmbito do município de Ituiutaba e da região do Pontal do Triângulo Mineiro. Assim, o principal objetivo do presente texto consiste em oferecer contribuições e subsídios para o debate a respeito da expansão e interiorização da pós-graduação no país, tendo em vista as experiências vivenciadas no âmbito do PPGEP/UFU.
Trajetória dos 40 anos do PPGEO/UFS nos estudos e pesquisas na Geografia brasileira
Authors: Santos Ana Rocha dos , Menezes Sônia de Souza Mendonça
Published: February 2025

O objetivo deste artigo é contribuir para o registro da história dos programas de pós-graduação em Geografia através da exposição da trajetória do PPGEO nos seus 40 anos de produção de conhecimento e formação de pesquisadores nos estudos geográficos. A metodologia utilizada baseou-se nos relatórios da Plataforma Sucupira, em fontes bibliográficas a respeito da história e desenvolvimento do Programa e nos depoimentos de professores que vivenciaram a criação dos cursos de pós-graduação em Sergipe. O PPGEO se caracteriza pelo pioneirismo na criação do curso de mestrado na UFS, sendo o segundo em Geografia da região nordestina, assim como pela instalação do primeiro curso de doutorado das regiões Norte e Nordeste. Além de atuar na formação para o exercício profissional, o PPGEO contribui para o enriquecimento da ciência geográfica pelo exercício intelectivo de professores e estudantes que aprofundam os estudos teóricos, realizam pesquisas empíricas e, com isso, fomentam a inserção social e o conhecimento historicamente acumulado.
Pesquisa, Ensino e Extensão no PPGEO-UERJ (Maracanã)
Authors: Tunes Regina , Oscar Júnior Antonio Carlos
Published: February 2025

A indissociabilidade entre ensino, pesquisa e extensão é uma diretriz da universidade pública brasileira, tanto nos cursos de graduação como de pós-graduação, e garantida na Constituição. No entanto, apesar da institucionalidade desse pilar, é preciso reconhecer que tanto do ponto de vista histórico, como pelas ações atuais, grandes são os desafios de implementação. Esse texto apresenta uma discussão sobre essas questões no âmbito do Programa de Pós-Graduação em Geografia (PPGEO) do Instituto de Geografia (IGEOG) da Universidade do Estado do Rio de Janeiro (Uerj) que comemorou em 2023 duas décadas de existência, momento este que foi marcado por reflexões sobre a história do programa, a contribuição das ações de ensino, pesquisa e extensão para a produção do conhecimento geográfico no Brasil e os desafios dos novos tempos.
A primeira década do Programa de Pós-Graduação em Geografia da Universidade Federal de Jataí
Authors: Martins Alécio Perini , Rodrigues Maria José , Oliveira Suzana Ribeiro Lima
Published: February 2025

O Programa de Pós-Graduação em Geografia – PPGGeo da Universidade Federal de Jataí, nível mestrado, entrou em funcionamento no ano de 2009 e o curso de doutorado, no ano de 2016. Este artigo tem como objetivo geral realizar uma avaliação da primeira década de implantação do PPGGeo a partir da perspectiva dos egressos do programa. Até o final de 2020, encerramento do quadriênio, 69% dos egressos responderam ao formulário da pesquisa. Entre os resultados, constata-se que o programa possui uma abrangência regional, com forte inserção no Centro-Oeste brasileiro, sendo de grande importância para a titulação de professores que atuam na educação básica e superior da região (65% dos participantes). Ainda, constatou-se que a avaliação realizada pelos egressos é condizente com o conceito 4 obtido pelo programa na avaliação quadrienal 2017-2020, indicando pontos em que o programa precisa avançar para o quadriênio seguinte.
A trajetória do Programa de Pós-Graduação em Geografia, da Universidade Estadual de Ponta Grossa
Authors: Fonseca Rosas Celbo Antonio da , Ornat Márcio José , Almeida João Paulo Leandro de
Published: February 2025

O presente artigo tem como objetivo analisar a trajetória do Programa de Pós-Graduação em Geografia da Universidade Estadual de Ponta Grossa-PR, desde a sua formação, até o seu presente momento de consolidação. Em menos de duas décadas, tivemos a aprovação do Mestrado em Gestão do Território (2005) e do Doutorado em Geografia (2012), resultado este da sinergia de um conjunto de docentes e discentes dispostos à produção da Ciência Geográfica, através de duas Linhas de Pesquisa: Dinâmicas Naturais e Análise Socioambiental, e Análises Socioeconômicas e Dinâmicas Regionais e Urbanas. Essa sinergia contou com o apoio da Universidade Estadual de Ponta Grossa, que com sua infraestrutura possibilitou a implementação de diversos projetos de pesquisa e de extensão, assim como as atividades de ensino, tripé basilar de uma Universidade Pública e Gratuita. Esta trajetória culminou na avaliação realizada pela Capes de conceito 5 no ano de 2017, e na confirmação deste conceito no ano de 2021, demonstrando sua consolidação.
Cenários hidroclimáticos em Barra dos Coqueiros/SE: vulnerabilidade socioambiental e resiliência urbana
Authors: Duarte Thiago , Pinto Josefa Eliane Santana de Siqueira
Published: February 2025

A ocorrência de eventos pluviais extremos em Barra dos Coqueiros, município localizado na faixa litorânea do estado de Sergipe, propicia o surgimento de cenários de vulnerabilidade socioambiental cuja causa remete aos processos de organização do espaço urbano, em especial à existência de falhas na rede de drenagem. Nesse sentido, citam-se os riscos de alagamentos, de transbordamento e de patologias por contaminação da via hídrica, bem como os riscos de inundações, deslizamento de terra, além da perda de patrimônio, de segurança e da própria vida daqueles que habitam a periferia semiestruturada da cidade. Diante da realidade apresentada, o objetivo deste trabalho de base sistêmica e metodologia qualitativa (com procedimentos de revisão teórica, levantamento cartográfico,  coleta de dados junto aos órgãos competentes e trabalho em campo) consiste em compreender como são distribuídos no espaço geográfico barracoqueirense os riscos socioambientais decorrentes dos eventos pluviais extremos, propondo soluções adaptativas e mitigadoras que contribuem para minimizar a situação de vulnerabilidade dos habitantes locais.
Editorial V15 N28
Authors: Santana Filho Manoel Martins de
Published: February 2025

Editorial
Early Cancer Detection: Hybrid Combination of Deep Learning and Computer Vision for Medical Images
Authors:   Ministry of Education, Wasit Education Directorate, Iraq, Oday Oday ,   Ministry of Education, Wasit Education Directorate, Iraq,   Computer Science and Information Technology, University of Wasit, Al Kut 52001, Iraq,   Ministry of Education, Wasit Education Directorate, Iraq, Shnan Fatima Hameed , Majeed Huda Lafta , Hassen Oday Ali
Published: February 2025

Medical imaging performs a critical position in modern healthcare, in particular in the early detection of cancers, which considerably enhances survival charges and treatment consequences. This study investigates a hybrid version combining Convolutional Neural Networks (CNNs) and Vision Transformers (ViTs) to optimize medical image analysis. Leveraging advanced deep gaining knowledge of strategies along with Transfer Learning and Data Augmentation, the hybrid method validated advanced performance in class, segmentation, and anomaly detection obligations. Experimental results discovered that the hybrid version outperformed standalone CNN and ViT architectures, attaining high diagnostic accuracy whilst keeping computational efficiency. The findings spotlight the potential of AI-stronger answers to revolutionize clinical diagnostics by way of offering accurate and reliable computerized systems, paving the manner for broader medical programs and improved patient results.
An IoT Framework for Emotion Detection and Behavior Influence: Towards Improving the Quality of Life
Authors:   Department of Computer Science, Faculty of Computers and Information, Mansoura University, Mansoura 35516, Egypt, Nada Nada ,   Department of Computer Science, Faculty of Computers and Information, Mansoura University, Mansoura 35516, Egypt,   Department of Computer Science, Faculty of Computers and Information, Mansoura University, Mansoura 35516, Egypt, Handosa Mohamed , Rashad M. Z.
Published: February 2025

Accurate emotion detection is crucial for individuals facing communication barriers, yet existing approaches struggle with real-time limitations and information Individual privacy. This research presents a new IoT-based framework that integrates EEG and physiological signals from wearable sensors with deep learning models, including CNN, Decision Trees, SVM, KNN, and Naïve Bayes. Unlike traditional methods, our approach effectively mitigates data latency and sensor noise while ensuring compliance with GDPR and HIPAA standards. Experimental results demonstrate a validated accuracy of 99-100%, outperforming state-of-the-art models. These developments establish our framework as a game-changing instrument for affective computing applications, enhancing human-machine interaction and healthcare quality of life.
NASICON-type V-based phosphate cathodes for sodium-ion batteries
Authors: Guo Jin-Zhi , Wu Xing-Long
Published: February 2025

Sodium-ion batteries (SIBs) with abundant raw materials and cost-effectiveness, are regarded as promising technologies for energy storage. Among various cathode materials, NASICON-type vanadium-based phosphates exhibit exceptional sodium storage capabilities. Nevertheless, low energy density, inadequate electronic conductivity, the toxicity of vanadium, and elevated costs hinder its practical application. In order to advance the practical applicability of polyanionic vanadium phosphate, current research efforts are concentrated on formulating effective strategies for improving the electrochemical performance. Consequently, this perspective focuses on the research progress of V-based phosphate cathode materials from the lattice regulation strategies, including the effects of single or double regulation of cation and anion sites on their local crystal/electronic structure, electrode reaction kinetics, Na+ migration path, sodium storage properties and mechanisms. Furthermore, the remaining challenges and personal outlooks about the future development of NASICON-type phosphate cathodes are presented. This review aims to inspire the rational design of advanced polyanion cathode materials for SIBs.
Advances in Organ-on-a-chip Technologies for Biomedical Research and Applications
Authors: Zhu Qian , Liao Menghui , Hu Yangnan , Chai Renjie
Published: February 2025

Recent breakthroughs in micro-nano fabrication and tissue engineering have accelerated the evolution of organoids and organ-on-chips (OOCs), offering a novel in vitro modeling strategy for human organ physiology. OOCs leverage microfluidic systems to replicate organ-specific microenvironments, providing a dynamic and configurable platform that simulates human biology for drug discovery and disease modeling. These technologies overcome the limitations of traditional in vitro systems and animal models, with organoids enhancing disease progression insights and OOCs enabling reproducible, high-throughput tissue functionality assessment. Despite the establishment of various disease models and the successful commercial transition of certain OOC platforms, high costs and research limitations underscore the need for continued technological innovation and standardization.
This review examines the current capabilities and challenges of OOCs in drug screening, disease modeling and personalized medicine, emphasizing their potential to refine evaluation processes with greater precision.
Electrochemical rapid reconstruction of 1D ZIF-L derived hollow hierarchical multiphase NiCo-S for high-performance hybrid supercapacitors
Authors: Shi Weidong
Published: February 2025

The combination of low electronegative sulfur and common transition metals has obvious advantages in easing volume expansion and improving electrical conductivity for energy storage. Herein, we developed an electrochemically assisted strategy to rapidly reconstruct ZIFs (Zeolitic Imidazolate Frameworks) with Lewis acid to obtain reticulated cross-linked hierarchical electrode NiCo-LDH@CNFs (carbon-nitrogen frameworks) with excellent active specific surface area. Simple vulcanization can effectively optimize the active site and crystal structure, and further improve the conductivity of the multi-phase electrode NiCo-S@CNFs (NiCo2S4, CoS2). Furthermore, the synergistic effect of multi-phase metal sulfides and the reasonable structure can effectually enhance the redox activity, adsorption capacity of OH-, and reduce the volume expansion and of the electrode. The results demonstrate that the specific capacity of the electrode is 433.3 mAh g-1 (6 M KOH). The prepared HSC device (hybrid supercapacitor, NiCo-S@CNFs//AC (activated carbon)) exhibits a maximum energy density of 87.2 Wh kg-1 (800 W kg-1). After 12,000 charge/discharge cycles, the capacity retention rate is still 105.1%, which has excellent cycling stability among ZIF-derived binary metal sulfides. Furthermore, parallel-connected LEDs can be lit by two series-connected HSCs, showing their practicality and great potential.
Ukraine: Party politics, the Left and President Zelensky: An interview with Professor Olexiy Haran
Authors: Barreto Marina Slhessarenko
Published: February 2025

The following interview with Professor Olexiy Haran highlights significant aspects of recent political developments in Ukraine. Departing from the dissolution of the Soviet Union, the professor reconstructs the role of leftist forces – whether socialist or communist –, alongside the unstable party system and its cleavages, as well as a series of political upheavals, not to mention the Russian invasion in 2014 and its full-scale war from 2022 on. The discussion portrays both social and institutional features of politics, encompassing social movements and political parties; it goes from fight against corruption to lustration laws; from civil criticism to war decisions. Throughout the interview, the scholar also cites relevant material for further readings and concludes by summarizing some paradoxes inherent to the current situation of the country.
Travessias da digitalização: da internet à inteligência artificial
Authors: Santaella Lucia
Published: February 2025

Desde 2017 no Brasil, a inteligência artificial (IA) começou uma jornada de presença crescente na economia, política, ciência e cultura até alcançar o estado de onipresença. As redes, os jornais, as revistas acadêmicas e os livros são distribuídos em tal volume todos os dias a ponto de se constituir em um verdadeiro dilúvio de informações que acabam por trazer mais confusão do que elucidação. Diante disso, o objetivo deste artigo é seguir o histórico de desenvolvimento da era da internet de modo a marcar os passos decisivos que foram gradativamente mergulhando as sociedades em contradições e ambivalências. É esse cenário que a inteligência artificial encontrou e à sua maneira intensificou.
O lítio no Brasil: história, políticas e desafios industriais
Authors: Santos Elaine
Published: February 2025

O lítio, um metal leve com alto potencial eletroquímico, desempenha um papel central na transição energética e na descarbonização, sendo essencial para o desenvolvimento de baterias recarregáveis usadas em energias renováveis, dispositivos eletrônicos e mobilidade elétrica. Com a crescente demanda global, há um aumento significativo na busca pelo lítio, tanto em termos de sua mineração quanto no controle de toda a cadeia produtiva, desde a extração nas minas até a fabricação de baterias. Este artigo analisa a evolução histórica do lítio no Brasil, desde sua exploração inicial até sua industrialização. Utiliza-se uma metodologia qualitativa, baseada em análise bibliográfica e documental, incluindo relatórios, artigos científicos e publicações governamentais. A análise busca construir uma narrativa contextualizada explorando as interações entre a indústria do lítio e as dinâmicas sociais e políticas no Brasil. Ao sistematizar a história da exploração e industrialização do lítio, o artigo contribui para a compreensão do papel desta indústria no contexto brasileiro contemporâneo oferecendo uma base para estudos futuros sobre os impactos sociais e a importância do controle dessa cadeia na transição energética.
Perspectivas sobre o ensino de história indígena presentes na primeira turma do Profhistória (2014-2016)
Authors: Schütz Kerollainy Rosa
Published: February 2025

este artigo tem o objetivo de pensar o ensino de história indígena a partir das pesquisas de professores que fizeram parte da primeira turma do Mestrado Profissional em Ensino de História (ProfHistória). Após um exercício de pesquisa e seleção desenvolvidos através do site do ProfHistória e do Portal eduCapes, foram escolhidas 9 dissertações que, tendo sido realizadas entre os anos de 2014 e 2016, se propuseram a abordar, como temática central, a temática indígena e a Lei 11.645/2008. Esta medida tornou o ensino dos povos indígenas obrigatório em todo o país e, consequentemente, se constitui enquanto um instrumento legal importante para a prática dos professores-pesquisadores. Sendo assim, são privilegiados os aspectos teóricos presentes nas dissertações, em especial aqueles que possibilitam estabelecer conexões entre as diferentes pesquisas e experiências dos professores. A presente análise permite compreender que, entre todas as pesquisas selecionadas, há por parte dos professores a tendência a buscar um olhar histórico que privilegie os protagonismos e narrativas indígenas, em consonância com as discussões mais recentes no ensino de história indígena.
The Use of soil amendments in crop production: A review
Authors:   Department of Crop Production and Agricultural Technologies, University of Namibia, Namibia, Enguwa Kuume , Horn Lydia ,   Multi-disciplinary Research Service, University of Namibia, Namibia, Awala Simon ,   Department of Crop Production and Agricultural Technologies, University of Namibia, Ogongo, Namibia
Published: February 2025

The fertility status of the Namibian soils is very low. In some parts of the country, such as the semi-arid Central Namibia, this phenomenon is much more extreme and, hence, a significant setback for crop growers. The soils are primarily sandy and lack organic matter, further worsened by low precipitation, high temperatures, and high evapotranspiration rates. This paper provides a background on soil amendments, including the two primary ways of categorising them based on the origin and the composition of the material(s) forming the amendments. Secondly, it offers a historical overview of the general agricultural use of soil amendments. Lastly, the paper discusses different soil amendments currently used and their effects on the fertility and productivity of agricultural soils. It is recommended that the effectiveness and the optimal application ratios of locally available soil amendments for crop production be studied.
Bilateral Brachial plexus block: A case report
Authors: Galadima Ibrahim , Yusuf tijjani , Aljannare bashir , Abdullahi muhammad , Bala mujtaba
Published: February 2025

Brachial plexus block is a very good alternative to general anaesthesia in upper limb surgeries. However, its bilateral use is not routinely practised because of the fear of complications such as phrenic nerve palsy, pneumothorax, and local anaesthetic systemic toxicity. With the introduction of ultrasound into the practice of regional anaesthesia, these blocks are increasingly becoming safe. We report to share our experience on a case of bilateral brachial plexus block in a 45 year old man with bilateral distal radial fractures, and blunt chest injury with multiple right sided rib fractures..
From Clues to Convictions: The Critical Role of Artificial Intelligence in Criminal Investigations.
Authors: Merdas Hussam
Published: February 2025

Justice is one of the foundations of daily life. It is one of the most important principles on which humanity was built, if not the most important. Human society is a mixture of good and evil people. To establish the principle of goodness and justice, it is necessary to employ all possible components in the contemporary era. At the forefront of these components are artificial intelligence tools. Artificial intelligence has now become a means that can be relied upon in many fields. One of the most important of these fields is criminal investigations. This study deals with the most important applications of artificial intelligence in the field of criminal investigations, including the most important modern studies and advanced technologies. Thecrime consists of several pillars, the most important of which are clues, the accused, the victim, and convictions. Here comes the employment of all artificial intelligence techniques to link the elements of the crime to reach the actual negligent party and thus achieve justice. This study also contributes to a practical application of the most important algorithms used to predict the occurrence of crime. The proposed work environment gave promising results, with prediction accuracy reaching (99.4). This study will discuss artificial intelligence techniques and their contemporary applications to provide a research summary for researchers and readers to start from in preparing their research or even design other useful techniques in the field of employing artificial intelligence to establish justice
KHUNG GIÁM SÁT VÀ PHẢN ỨNG SỰ CỐ AN NINH TỰ ĐỘNG: THỰC HÀNH TỐT NHẤT CHO CÁC DOANH NGHIỆP VỪA VÀ NHỎ
Authors: Thành Nguyễn Hoàng , Thưa Huỳnh Trọng
Published: February 2025

Hiện nay, việc phản ứng sự cố an toàn thông tin tại các doanh nghiệp vừa và nhỏ (SME) chủ yếu dựa vào Đội phản ứng sự cố của đơn vị đó (nếu có) hoặc nhờ sự trợ giúp của Lực lượng phản ứng sự cố của Cục An toàn thông tin thuộc Bộ Thông tin và Truyền thông. Trên thế giới, việc phản ứng với sự cố an toàn thông tin chủ yếu được thực hiện theo các hướng dẫn của bộ tiêu chuẩn ISO 27001 và ISO 27002. Trong một môi trường mà các mối đe dọa mạng liên tục phát triển, khả năng thích ứng nhanh chóng và hiệu quả là rất quan trọng. Các hệ thống giám sát và phản ứng sự cố tự động không chỉ là một sự tiện lợi mà là một điều cần thiết để bảo vệ thông tin nhạy cảm, duy trì tính liên tục trong kinh doanh và tuân thủ các yêu cầu quy định. Mặc dù có khá nhiều giải pháp, nền tảng giám sát và xử lý sự cố an toàn thông tin, nhưng hầu hết rất đắt tiền, tính tự động hóa thấp đòi hỏi nguồn nhân lực chất lượng cao, khó tìm, không phù hợp với số đông SME. Khung kiến trúc đề xuất trong nghiên cứu này là sự kết hợp các dữ liệu log thu thập được trên hệ thống giám sát và các kỹ thuật phản ứng sự cố tự động, hiện đại và phức tạp nhằm gia tăng hiệu quả phòng chống tấn công hệ thống thông tin, giúp doanh nghiệp chủ động và làm chủ được công nghệ trong việc tự phát triển và triển khai một hệ thống giám sát và phản ứng tự động với các sự cố an ninh thông tin.
THỰC TRẠNG PHẨM CHẤT, NĂNG LỰC ĐỘI NGŨ GIẢNG VIÊN Ở MỘT SỐ TRƯỜNG ĐẠI HỌC TƯ THỤC TẠI THÀNH PHỐ HỒ CHÍ MINH
Authors: Nhật Nguyễn Văn
Published: February 2025

Phẩm chất, đạo đức và năng lực của đội ngũ giảng viên (ĐNGV) là yếu tố sống còn đối với sự phát triển của các trường đại học tư thục (ĐHTT), nhất là trong bối cảnh cạnh tranh ngày càng gay gắt hiện nay. Những tiêu chuẩn về đạo đức, lối sống và tác phong không chỉ là yêu cầu cần thiết cho mỗi cá nhân giảng viên mà còn góp phần khẳng định uy tín, chất lượng của nhà trường. Ngoài phẩm chất đạo đức, năng lực giảng dạy và kỹ năng chuyên môn là yêu cầu thiết yếu để ĐNGV đáp ứng được đòi hỏi ngày càng cao trong đào tạo. Kết quả nghiên cứu cho thấy phẩm chất và năng lực của ĐNGV các trường ĐHTT tại TP.HCM được đánh giá cao, tuy vẫn còn một số mặt hạn chế, đặc biệt là trong lĩnh vực NCKH và kỹ năng ngoại ngữ, tin học. Kết quả nghiên cứu này mang lại giá trị thiết thực trong việc cung cấp cái nhìn tổng quan về thực trạng phẩm chất, năng lực ĐNGV các trường ĐHTT tại TP.HCM. Những phát hiện từ nghiên cứu không chỉ giúp các nhà quản lý giáo dục nhận diện rõ ràng các vấn đề cần cải thiện mà còn là cơ sở để các trường xây dựng chiến lược phát triển nguồn nhân lực giảng dạy trong tương lai. Việc nâng cao chất lượng ĐNGV sẽ không chỉ góp phần cải thiện chất lượng đào tạo, mà còn gia tăng uy tín của các trường ĐHTT, từ đó nâng cao khả năng cạnh tranh với các cơ sở đào tạo trong hệ thống giáo dục.
Sleeping outside the lines
Authors:   , Bouman Emma Jantine
Published: February 2025

This thesis focuses on the association between social jetlag, a chronic mismatch between social and biological sleep timing, and markers of glycemic and metabolic control. In part 1, we examined whether social jetlag is associated with glycemic and metabolic control in the general population and in people with type 2 diabetes. We found cross-sectional associations with BMI, waist circumference, blood pressure and glucose levels, but no consistent prospective associations. In part 2, we studied mechanistic pathways that could explain these associations. We found that lifestyle factors partly explain the association between social jetlag and BMI but we could not confirm other proposed pathways and these remain to be studied. Part 3 of this thesis describes a study protocol of a randomized controlled trial that aims to reduce social jetlag and assess the effects on glycemic and metabolic control. This study is ongoing and still needs to point out whether reducing social jetlag could improve health. More attention for sleep and sleep timing in addition to dietary and physical activity guidelines could help in the prevention of conditions such as the metabolic syndrome and type 2 diabetes. Also, more general awareness of the importance of our sleep timing and more flexible school start times and work schedules could help reduce social jetlag.
Optimizing vincristine treatment in European and sub-Saharan African children with cancer
Authors:   , Uittenboogaard Aniek
Published: February 2025

incristine is a chemotherapeutic agent that has been used for decades in the treatment of children with cancer. It exerts its cytotoxic effect through binding to tubulin,
an important component of the cytoskeleton. The main side-effect of vincristine,
vincristine-induced peripheral neuropathy (VIPN), often manifests as tingling, numbness and pain in the hands and feet and patients can experience muscle weakness and
loss of peripheral reflexes. Vincristine is especially important in low- and middle-income
countries (LMICs) given its availability, affordability, and relatively low risk of myelosuppression. However, there remains uncertainty about the optimal dosing regimen.
Historically, dosing guidelines were developed in high-income countries (HICs) based
on data from predominantly white patients. Other populations, such as in LMICs, may
benefit from adapted or individualized dosing guidelines that consider differences in
genetics, pharmacokinetics (PK) or side effects like VIPN. Therefore, the main research
question investigated in this thesis is: How can vincristine treatment be optimized to
balance toxicity and efficacy in European and black sub-Saharan children with cancer?
Chapters 2 and 3 describe the treatment outcomes of Kenyan children diagnosed with a
Wilms tumor and retinoblastoma, highlighting the gap in survival between children with
cancer in LMICs and HICs. Chapter 4 presents a systematic review and meta-analysis on
the influence of pharmacogenomic parameters on the development of VIPN. Chapter
5 reports a prospective study in which the association between pharmacogenomic parameters and the PK of vincristine and VIPN was assessed. Chapter 6 details the results
of a randomized controlled trial in which the long-term effect of giving vincristine as a
one-hour infusion instead of a push injection on the development of VIPN was studied.
In Chapter 7, the development of a pharmacometric nomogram that identified Kenyan
children with a subtherapeutic vincristine exposure is described. Chapter 8 follows with
a study on vincristine exposure and VIPN in Kenyan children, in which dose-escalation
was implemented in case of low exposure. Chapter 9 describes the differences in
vincristine PK between Kenyan, Malawian and European children. Chapter 10 provides
a practical guideline and minimal requirements for performing clinical pharmacology
investigator-initiated studies including PK sampling in resource-limited settings. Finally,
in Chapter 11, the key findings of this thesis are discussed in the context of the literature
and recommendations for future research are provided.
The Effect of the Video "Young Smart Without Drugs" Is Effective In Increasing Adolescents' Knowledge About Drugs
Authors: Mumpuniati Septalia , Arfan Iskandar , Suwarni Linda
Published: February 2025

Background: The prevalence of drug abuse in 2019 was 0.80% of the total population of West Kalimantan province. Students, especially at the high school/vocational level, are at the top of the drug abuse list. Objective: This study aims to determine the effectiveness of education through animated video media "Young Smart Without Drugs" on adolescents' knowledge about drugs in class XI at SMK Negeri 4 Pontianak. Methods: This research is a pre-experimental research with one group pretest and posttest design. The population in this study were all grade XI students at SMK Negeri 4 Pontianak in the 2021/2022 school year, totaling 592 students. Results: There is a significant difference in knowledge before the intervention (4.80) and after the intervention (9.73) of the animated video education "Young Smart Without Drugs".  The test results obtained a p value of 0.000 <0.05.  Conclusion: Animated video media "Young Smart Without Drugs" can be an alternative media used in education to increase adolescents' knowledge in preventing drug abuse.
O EFEITO DA ASSISTÊNCIA TÉCNICA NA QUALIDADE DO LEITE DE PRODUTORES NA REGIÃO DO TRIÂNGULO MINEIRO
Authors: Mota Patrícia Vaz de Melo , Vieira Simone Melo
Published: February 2025

Objetivou-se avaliar os impactos da assistência técnica em relação à contagem padrão em placas (CPP), adotando como referência o valor máximo permitido de acordo com a Instrução Normativa 76. Os dados da pesquisa foram obtidos em três municípios da região do Triângulo Mineiro e envolveu a coleta quinzenal de amostras de leite pelo laticínio que captava o leite nestas regiões. As propriedades leiteiras pesquisadas corresponderam a cinco no município de Uberlândia, cinco em Tupaciguara e cinco em Monte Alegre de Minas. Essas propriedades apresentavam alta contagem de bactérias e necessitavam da intervenção da assistência técnica visando a redução da carga microbiana. Foram coletadas 195 amostras de leite no tanque de refrigeração dessas propriedades para monitoramento da CPP no período de fevereiro a agosto de 2022. As amostras foram encaminhadas e analisadas pelo laboratório da Clínica do Leite da ESALQ/USP em Piracicaba/SP. Para interpretação do efeito da intervenção técnica, os dados das análises foram organizados em planilha de Excel para cálculo das médias e desvio padrão. Durante o período avaliado, todas as propriedades apresentaram redução na CPP, permanecendo-se abaixo do valor exigido pela IN 76 (300.000 UFC/mL). As propriedades apresentaram oscilações nos resultados de CPP durante o período analisado, porém, ao final da pesquisa, constatou-se que a porcentagem de produtores com média abaixo de 300.000 UFC/mL foi de 100% em Monte Alegre de Minas e 60% em Uberlândia e Tupaciguara. Concluiu-se a importância da assistência técnica e o acompanhamento ao produtor para que se obtenha uma melhor qualidade do leite cru.
Methodological reflections on research with racialized communities and stigmatized topics: Towards a model of transformative engagement
Authors: Sato Christa , Espina F. J. , Landers Ashley L. , McLuckie Alan , Este David
Published: February 2025

Through our participation as the Calgary site for the Strength in Unity (SIU) project, a pan-Canadian randomized controlled trial, our team anticipated learning much about the seldom researched area of racialized men’s experiences with mental health stigma and their responses to novel interventions. Distinct from the study’s formal objectives and research queries, we encountered significant recruitment challenges, which engendered unanticipated but welcomed learnings concerning culturally sensitive recruitment practices. To help build the capacity of researchers to meaningfully and respectfully engage ethnoculturally diverse populations, this article discusses five major approaches to participant recruitment and engagement used by the Calgary-based SIU team, as well as the strengths and limitations of each identified approach. In this critical commentary we examine conventional recruitment processes employed in Calgary during early stages of the broader SIU study, thereby illuminating unanticipated barriers to the success of these accepted recruitment practices, as well as report lessons learned that may benefit projects endeavoring to use community-based recruitment strategies to engage participants from diverse cultural groups, particularly for projects considering matters stigmatizing (real or potential) to the community or communities of interest. From our serendipitous learnings we proffer the terminology, “transformative engagement” to characterize a novel process for social work researchers (and/or allied health professionals) to engage with communities and peoples in meaningful, respectful, lasting, and transformative processes, that move beyond traditional and even culturally-sensitive research recruitment practices.
US Constitution and the Notion of Family : The risks of the Supreme Court’s judicial activism through family and privacy cases
Authors: Molnár Sarolta Judit
Published: February 2025

This paper examines the family and privacy jurisprudence exercised by the United States Supreme Court. These cases have provoked a substantial amount of attention from the public and politics in the history of the Court. Arguments for the decisions have been widely debated, criticized, and discussed. Arguably, some of these cases have even changed the role of the Court, the culture of the American nation, and the structure of the American society. The paper attempts to investigate these issues in detail and pose a federalist argument shedding light on the dangers of judicial activism regarding the institutions of a democratic state.
ESL learners writing classified advertisements online
Authors:   Ph.D. Scholar  Department of Education  University of Delhi, Kanika Kanika
Published: February 2025

The research objectives of this study were to analyse the technology-mediated classified ad writing task done by the class xi ESL learners in groups in a physical classroom and the conversations that took place while doing the task. The data was collected through screenshots of the classified ad made by the learners using a tab, screen recordings of the task and teacher-learner conversation recordings. Descriptive statistics were used to analyse the classified advertisements created by the learners. A thematic analysis of their conversations was done. The results revealed that...Their conversation analysis revealed their discussions centred around the content and language of the task, technical difficulties faced, knowledge of technology and attitude towards doing tasks mediated by technology. The implications are that technology-mediated writing tasks require sufficient infrastructure and technical assistance. Learners find such tasks interesting. It builds their language skills and digital literacy in the process.

Keywords

Technology-mediated task-based language learning, Learning English as a second language, learning writing skills, Digital literacy, Task analysis
Advancements in Thermionic Energy Conversion for Waste Heat Recovery in Automotive Systems: A Comprehensive Review
Authors:   1Mechanical Engineering Department, Deogiri Institute of Engineering and Management studies, Aurangabad, Tamboli Mayur A.
Published: February 2025

Thermionic Energy Conversion (TEC) is emerging as a transformative technology for improving energy efficiency in Hybrid Electric Vehicles (HEVs) by converting high-temperature waste heat into electricity. This review explores the evolution of TEC systems, focusing on recent advancements in materials like tungsten, molybdenum, and graphene. It delves into design considerations, challenges of thermal stress management, and integration strategies within automotive exhaust systems. Key research gaps and future opportunities, such as real-world validations and innovative material coatings, are discussed to foster further adoption in sustainable automotive solutions.

Key Words: Thermionic Energy Conversion, Hybrid Electric Vehicles, Waste Heat Recovery, Tungsten, Graphene, Thermal Stress.
Kroniek rechtspraak civiel recht
Authors: de Ridder M.J.J.
Published: February 2025

Kroniek rechtspraak civiel recht

In deze kroniek worden in het kort de belangrijkste ontwikkelingen in de jurisprudentie in de jaren 2010 en 2011 besproken. Als nieuwe ontwikkelingen zijn onder meer te noemen beschikkingen in deelgeschillen en uitspraken op het gebied van de Wet bescherming persoonsgegevens. Er wordt onder meer ingegaan op uitspraken op het gebied van integriteitschade, de aansprakelijkheid van de hulpverlener door gebruikmaking van een gebrekkige hulpzaak, onrechtmatige uitlatingen over zorgverleners op internet en de causale toerekening, waarbij aan de orde is of deze al dan niet wordt doorbroken door het feit dat de patiënt zelf in de gelegenheid is de schade te voorkomen.
Staat het medisch beroepsgeheim rechtshandhaving in de relatie tussen IGZ en OM in de weg?
Authors: Schalken T.M.
Published: February 2025

Staat het medisch beroepsgeheim rechtshandhaving in de relatie tussen IGZ en OM in de weg?

In de praktijk komt het geregeld voor dat het OM patiëntgevoelige gegevens opvraagt bij de IGZ. Hoe verhoudt deze praktijk zich tot de medische geheimhoudingsplicht van de arts of zorginstelling die deze gegevens aan de IGZ heeft afgestaan, zodat ook de IGZ aan een geheimhoudingsplicht is gebonden? De auteur bespreekt in dit artikel enkele argumenten die van belang zijn bij de beantwoording van de vraag of de IGZ verplicht dan wel bevoegd is de gevorderde patiëntgegevens aan het OM te verstrekken alsmede of het OM die gegevens al dan niet in of ten behoeve van een strafzaak mag gebruiken.
Prenatale screening in het licht van zelfbeschikking
Authors: van Hellemondt R.E. , van Os E.C.C. , Hendriks A.C. , Breuning M.H.
Published: February 2025

Prenatale screening in het licht van zelfbeschikking

Informatie is van groot belang voor het uitoefenen van zelfbeschikking bij prenatale screening. Gezondheidsraad, regering en parlement hechten veel waarde aan gestandaardiseerde informatie en een non-directieve attitude van diegene(n) die de zwangere begeleidt in het kader van het landelijk programma prenatale screening. Echter, voor het borgen van zelfbeschikking van zwangeren is het belangrijk dat het informeren over prenatale screening wordt opgevat als een sociaal-dialogisch proces dat verder reikt dan het geven van feitelijke informatie. Daarenboven is het noodzakelijk dat de leeftijdsgrens voor de vergoeding van de combinatietest wordt losgelaten, opdat zwangeren daadwerkelijk keuzevrijheid hebben bij beslissingen rond prenatale screening op Downsyndroom.
Postmortale eiceldonatie: wat is er tegen?
Authors: Dondorp W.J. , de Wert G.M.W.R.
Published: February 2025

Postmortale eiceldonatie: wat is er tegen?

Hoewel de Embryowet postmortale donatie van geslachtscellen onder voorwaarden toestaat, is er discussie over de vraag of het gewenst is die mogelijke bestemming op te nemen in de bewaarovereenkomst voor gecryopreserveerde eicellen. Gelet op de grote schaarste aan donoreicellen denken wij dat er geen goede reden is om al bij voorbaat aan deze mogelijke bron voorbij te zien. We vermoeden dat de bezwaren tegen postmortale eiceldonatie samenhangen met een aanvechtbare visie op het belang van de persoon van de donor voor het welzijn van het toekomstige kind.
Privacy van patiënten is onvoldoende gewaarborgd bij de doorstart van het EPD
Authors: Koelewijn W.I.
Published: February 2025

Privacy van patiënten is onvoldoende gewaarborgd bij de doorstart van het EPD

In deze bijdrage wordt onderzocht wat de verwerping van het wetsvoorstel ‘Kaderwet EPD’ en de privaatrechtelijke doorstart van het elektronisch patiëntendossier betekent voor de rechtspositie van patiënten. Bij de doorstart worden op grote schaal privacygevoelige patiëntengegevens verwerkt zonder formeel-wettelijke grondslag en zonder dat is voorzien in aanvullende patiëntenrechten. De doorbreking van het medisch beroepsgeheim en de verwerkingsgrondslag van patiëntgegevens worden daarmee volledig gebaseerd op de uitdrukkelijke toestemming van de betrokken patiënten. De auteur plaatst diverse kritische kanttekeningen bij deze juridische constructie en komt tot de conclusie dat de rechtspositie van patiënten bij de doorstart van het EPD onvoldoende is gewaarborgd.
Grensoverschrijdend patiëntenverkeer in de Zorgverzekeringswet: is de voorgenomen wijziging van artikel 13 Europeesrechtelijk houdbaar?
Authors: van de Gronden J.W.
Published: February 2025

Grensoverschrijdend patiëntenverkeer in de Zorgverzekeringswet: is de voorgenomen wijziging van artikel 13 Europeesrechtelijk houdbaar?

De regering heeft voorgesteld om artikel 13 Zorgverzekeringswet te wijzigen. Het doel hiervan is om zorgverzekeraars de mogelijkheid te bieden om niet-gecontracteerde zorg, ook die ondergaan is in het buitenland, niet te vergoeden. Volgens de regering zou de EU-richtlijn betreffende de toepassing van de rechten van patiënten bij grensoverschrijdende gezondheidszorg dit toestaan. Nagegaan wordt of deze stelling hout snijdt. Bij de auteur bestaat de zorg dat bij onjuiste implementatie van Richtlijn 2011/24 zich vele ingewikkelde Europeesrechtelijke kwesties zullen voordoen. Dit zou ten koste gaan van de patiënt.
De Inspectie opnieuw onderzocht
Authors: Kahn Ph.S.
Published: February 2025

De Inspectie opnieuw onderzocht

Eind 2012 verschenen in een lange reeks opnieuw twee rapporten over de IGZ: van Sorgdrager en van Van der Steenhoven. Beide onderzoekers verlangen van de Inspectie enerzijds een sterk op de individuele burger gerichte (procedurele) taak met betrekking tot klachtbehandeling, anderzijds een focus met betrekking tot het systeemtoezicht waarmee zij sinds 1995 is belast. Beide gaat niet samen. Een fundamentele discussie over de rol van de IGZ wordt echter uit de weg gegaan. Hierdoor wordt de verwarring over de positie van de IGZ vergroot en leidt dit tot gezag- en reputatieverlies van de Inspectie, hetgeen zeer ongewenst is.
Actieve openbaarmaking van informatie door IGZ: het wetsontwerp tot wijziging van de Gezondheidswet
Authors: van der Jagt-Jobsen J.A.E. , Nijveld O.S.
Published: February 2025

Actieve openbaarmaking van informatie door IGZ: het wetsontwerp tot wijziging van de Gezondheidswet

In deze bijdrage wordt het wetsontwerp besproken dat strekt tot invoering van een specifieke wettelijke grondslag voor actieve openbaarmaking van informatie over het toezicht en de uitvoering van regelgeving door IGZ. Achtereenvolgens komen de doelen van het wetsontwerp, de te openbaren gegevens, de gronden om informatie niet te openbaren, de rechtsbescherming tegen openbaarmaking en procedurele bepalingen over de openbaarmaking aan de orde. De auteurs zijn van mening dat het wetsontwerp een goede aanzet vormt tot het op grotere schaal actief openbaar maken van toezichtgegevens door IGZ. Zij plaatsen evenwel met name kanttekeningen bij de wijze waarop het wetsontwerp de rechtsbescherming tegen beslissingen tot actieve openbaarmaking regelt.
Verslag Najaarsvergadering Vereniging voor Gezondheidsrecht 2012
Authors: van Hellemondt R.E.
Published: February 2025

Verslag Najaarsvergadering Vereniging voor Gezondheidsrecht 2012

Verslag van de najaarsvergadering van de Vereniging voor Gezondheidsrecht (VGR) op vrijdag 2 november 2012 in de Domus Medica in Utrecht. De vergadering had als thema ‘zorgverlening aan jeugdigen’.
Het voorgestelde verbod op verticale integratie tussen zorgverzekeraars en zorgaanbieders
Authors: Plomp E.
Published: February 2025

Het voorgestelde verbod op verticale integratie tussen zorgverzekeraars en zorgaanbieders

Wetsvoorstel 33 362 introduceert in de Wet marktordening gezondheidszorg een verbod op verticale integratie tussen zorgverzekeraars en zorgaanbieders. Het verbiedt zorgverzekeraars, AWBZ-verzekeraars en zorgkantoren om (a) zelf zorg te verlenen en (b) direct of indirect zeggenschap te hebben over een zorgaanbieder. In dit artikel wordt betoogd dat dit verbod niet noodzakelijk en niet proportioneel is om het daarmee beoogde doel te bereiken. Gewezen wordt op het belang om (alternatieve) maatregelen te nemen om het vertrouwen in zorgverzekeraars en de transparantie met betrekking tot de kwaliteit van zorg te verbeteren.
Kroniek rechtspraak civiel recht
Authors: de Ridder M.J.J.
Published: February 2025

Kroniek rechtspraak civiel recht

In deze kroniek worden in het kort de belangrijkste ontwikkelingen in de jurisprudentie besproken in de periode van 1 september 2011 tot en met 1 juni 2013. Daarbij wordt eerst ingegaan op de diverse gronden waarop de aansprakelijkheid kan worden gebaseerd: schenden van de zorgplicht, niet nakomen van een protocol, schenden van een veiligheidsnorm, schenden van een toezichthoudende taak; gebruik maken van een gebrekkige hulpzaak, aansprakelijkheid van een producent en het ontbreken van informed consent. Voorts wordt ingegaan op de voorwaarden die aan het causaal verband en toerekening kunnen worden gesteld, in welk kader ook de ontwikkelingen op het gebied van de omkeringsregel en de proportionaliteit en kansschade aan bod komen. Andere onderwerpen die in de kroniek worden besproken zijn: deskundigenberichten, verjaring en de Wbp.
Zorgplichtschending bij beroepsziekten; bewijsproblemen bij het causaal verband: de arbeidsrechtelijke omkeringsregel en het leerstuk van proportionele aansprakelijkheid
Authors: van Dijk Chr.H. , Veendrick L.L.
Published: February 2025

Zorgplichtschending bij beroepsziekten; bewijsproblemen bij het causaal verband: de arbeidsrechtelijke omkeringsregel en het leerstuk van proportionele aansprakelijkheid; HR 7 juni 2013, ECLI:NL:HR:2013:BZ1721 (Lansink/Ritsma) en HR 7 juni 2013, ECLI:NL:HR:2013:BZ1717 (SVB/Van de Wege)

Op 7 juni 2013 heeft de Hoge Raad twee belangrijke arresten gewezen over de aansprakelijkheid van de werkgever bij beroepsziekten ex artikel 7:658 BW. De arbeidsrechtelijke omkeringsregel wordt in de arresten van 7 juni 2013 wederom nader vormgegeven. Ook komt de zorgplicht van de werkgever bij beroepsziekten in deze beide arresten aan de orde. Tot slot wijdt de Hoge Raad enige overwegingen aan het leerstuk van proportionele aansprakelijkheid dat speelt bij onzeker causaal verband tussen de normschending en de schade. Reden genoeg dus om bij deze beide arresten stil te staan.