bluuebunny/crossref_metadata_2025 huggingface dataset:
Relationship between some element levels and oxidative stress parameters in rats liver treated with hydroxyurea derivative compounds
Authors: KARAGÖZOĞLU Yusuf , PARLAK Akif Evren , ALAYUNT Naci Ömer , TÜRKOĞLU Semra , YİLDİRİM İsil , KARATEPE Mustafa
Published: January 2020

In this study, effects of hydroxyurea derivatives 1, 3, 4 - thiadiazole and schiff base compounds on some element levels and antioxidant enzyme activities in rat liver and on antioxidant enzyme levels that are parameters of oxidative stress were investigated. For this purpose, iron (Fe), zinc (Zn) and copper (Cu) concentrations were analyzed by using atomic absorption spectroscopy superoxide dismutase (SOD) and catalase (CAT) activities were measured by using a UV spectrophotometer. Fe, Zn and Cu concentrations in the liver of rats treated with these compounds were compared with levels of SOD and CAT statistically. As a result, the increase in the antioxidant activities of SOD and CAT metalloenzymes together with decrease in levels of Cu, Zn and Fe elements observed may suggest that the elements be bound to these enzymes. 
Mouse models for retinal degeneration
Authors: SHU Xinhua
Published: January 2020

Retina is a part of central nervous system. Retinal degeneration is characterized by the death of photoreceptor cells, causing partial vision loss or even blindness. Retinal degeneration includes inherited retinal degeneration such as retinitis pigmentosa (RP) and complex retinal degeneration such as diabetic retinopathy. In this talk, I will discuss the disease mechanisms and current treatment of inherited retinal degeneration. I will also discuss techniques for retinal degeneration in mouse models.  I will demonstrate how to dissect mouse retina and retinal pigment epithelial (RPE) cells.   
Using fluorescent calcium indicators in neuronal ion channel studies
Authors: ÇİĞ Bilal
Published: January 2020

Calcium ion (Ca2+) is the most prominent secondary messenger of physiological cellular signals and ion channels research (Moeder et al. 2019). Neurotransmission, muscle contraction and fertilization are only a few of the physiological properties that make calcium ion important in most eukaryotic cells (Pharris et al.  2018). The extracellular calcium concentration is 1-3 mM whereas the intracellular concentration is around 80-100 nM. This tremendous difference is tightly controlled by dozens of different ion channels embedded in the membrane (Van Hook et al.  2019). Activation of these channels causes calcium ions to entry into the cell with density gradient. This produce the calcium signal. It is very important to control that prolonged elevation of intracellular calcium concentration due to channelopathies in ion channels due to various nervous system diseases because it activates caspase cascades leading to permanent damage and apoptosis. In this respect, the calcium indicators are unrivaled in terms of taking clear results by photographing all the points in these steps from the stage they were developed to the final stages. The use of these indicators to address the roles of these ion channels in terms of their contribution to the pathogenesis of neurological diseases has been an indispensible method of molecular analysis in recent years (Xu and Dong, 2019). In this presentation, we will discuss the chemical structures of calcium indicators, their contribution to the examination of cellular signaling pathways, their advantages and disadvantages in the investigation of ion channels in neurological diseases.
Ischemic stroke models in adult experimental animals
Authors: COŞAR Aymer
Published: January 2020

Hypoxic-ischemia is containing complex physiological, molecular and biochemical pathways and it is induced by lack of oxygen supply to the brain. Hypoxic ischemia induces severe brain injury in adults and newborns. Pathophysiology of ischemic stroke involves oxidative stress, mitochondrial energy production failure, excessive Ca2+ influx and apoptosis (Akpınar, et al., 2016). Investigation of the traumatic brain injuries in the subject are difficult due to ethical restrictions. Therefore, the animal models have great importance for the clarifying etiology of the ischemic stroke-induced brain injuries. However, there are differences between human rodent brains. Notable difference between the human and rodent is presence of developing brain (Gennaro et al. 2019). In experimental animals, the best model of induction of hypoxic cerebral ischemic stroke is occlusion of the middle cerebral artery for 30-60 min (Gennaro et al. 2019). In addition to the best model, there are also other models of hypoxic cerebral stroke in rodents such as hypoxiaischemia, thrombotic ischemia, vasoconstriction. Endothelin 1 and the distal artery compression models (Gennaro et al. 2019; Hermann et al. 2019).  In this presentation, I summarized the models currently used to investigate the human developmental ischemic stroke, describing their advantages and limitations. 
Potential therapeutic role of melatonin in traumatic brain injury: A literature review
Authors: ERTILAV Kemal
Published: January 2020

Oxidative stress induces excessive production of reactive oxygen species (ROS). ROS are including several free oxygen radicals such as singlet oxygen and superoxide radical. Excessive ROS production induces injuries of lipids, nucleic acids and proteins in several cells. Brain and neurons have a high amount of polyunsaturated fatty acids (PUFAs) and consumption of oxygen, but they have low level of antioxidant. Oxidative stress is controlled by several enzymatic and non-enzymatic antioxidants. One of the main nonenzymatic antioxidant is melatonin. Melatonin is secreted from the pineal gland by physiological circadian cycles. It has several physiological functions such as mediator of circannual reproductive rhythms (Tamtaji et al. 2019). However, it has also a regulatory role in the pathophysiological pathways of traumatic brain injury (TBI) in human and rodents (Barlow et al. 2019). TBI is one of the most common causes of the mortalities. Secondary events occur after primary events like shearing of nerve cells and blood vessels, cause posttraumatic neurodegenerations with an increase in ROS and ROS-mediated lipid peroxidation. It was reported that TBI-induced oxidative stress in experimental TBI was inhibited by the melatonin treatment (Senol and Nazıroğlu, 2014). Results of a recent study indicated protective role of melatonin through inhibition of Nrf2 signaling pathway, inflammation and oxidative stress in TBI-induced mice (Wang et al. 2019). In human studies, behavioral outcomes of TBI were modulated by the melatonin treatment (Barlow et al. 2019). In the oral presentation, I will review recent studies on TBI in human and experimental animals.   In conclusion, there are pre-clinical and clinical evidences that melatonin treatment after TBI significantly improves both behavior-cognition outcomes and pathophysiological outcomes such as oxidative stress and inflammation. It seems that the certain interaction between melatonin and TBI still remain to be determined.
Psychological and oxidative stress induce apoptosis through TRPV1 channel activation in granulosa cells of oocyte during in vitro fertilization
Authors: ULUSOY KARATOPUK Dilek
Published: January 2020

Several physiological and pathophysiological functions such as mitochondria and phagocytosis induce oxidative stress. Oxidative stress results in excessive production of reactive oxygen species (ROS). There is a high amount of psychologically and chemically stress in in vitro fertilization (IVF), because of presence stressful permanent infertility and treatment procedures (An et al. 2013). Oocytes are surrounded by granulosa cells. It is well-known that there is a direct relationship between oxidative stress contents of granulosa cells and oocyte quality (Tola et al 2013). Excessive Ca2+ influx induces excessive mitochondrial ROS production and apoptosis through activation of caspase activations. Involvement of voltage gated Ca2+ channels on oocyte quality and apoptosis in the granulosa cells has been clarified by results of several studies (Platano et al. 2013; Tola et al 2013). Transient receptor potential vanilloid 1 (TRPV1) channel is a calcium permeable and non-selective cation channel. The similar effects of voltage gated calcium channels may present between oxidative stress and TRPV1 channel activation in the oocyte, because the TRPV1 channel is activated by excessive production of ROS. The importance of TRPV1 channel on the oocyte maturation was recently reported (Cecconi et al. 2019).  In the oral presentation, I will review recent studies on apoptosis through TRPV1 channel activation in granulosa cells of oocyte during IVF.  In conclusion, current literature data indicated that psychological and oxidative stress-induced ROS, apoptosis and Ca2+ contents of oocyte and granulosa cells have very important roles on the oocyte maturation in patients with infertility during the IVF. There are some involvement clues of TRPV1 channels on the oocyte maturation and apoptosis, but the subject needs future studies. 
The Effects of Delayed Fluid Resuscitation on Lung Oxidative Stress and Antioxidant Vitamin Levels in Controlled Hemorrhagic Shock: An Experimental Study
Authors: BİRCAN Hacı Ahmet
Published: January 2020

We aimed to determine the effects of delayed

fluid resuscitation on the lung oxidative stress and antioxidant vitamin levels

in a rat model of controlled hemorrhagic shock (HS). Male Wistar rats were exposed to controlled HS via

arterial catheterization to reduce mean arterial pressure (MAP) to 40 mmHg over

10 minutes. Two groups were constituted

according to resuscitation time: early (n=6) and delayed (n=5), respectively

resuscitated 30 or 90 minutes after HS. A control group (n=5) was subjected to

catheterization only. Intravenous fluid resuscitation was done with Ringer lactate

solution. After 24 hours, bronchoalveolar

lavage (BAL) was performed and

the lungs were harvested for biochemical, cytological and histopathological analyses. Lipid

peroxidation (as MDA), reduced glutathione (GSH), glutathione peroxidase

(GSH-Px) and vitamin A, vitamin C and vitamin E levels were measured in both BAL fluid (BALF) and

lung homogenate. Lung tissue GSH-Px and vitamin E levels are increased

in both HS groups compared to the control group. No significant differences

were found in MDA, GSH, vitamin A and vitamin C BALF levels among

all groups, except for GSH-Px (p=0.007). Intracellular

antioxidants, especially GSH-Px and vitamin E, increase in the lungs of rats

(in both HS groups), possibly due to increased oxidative stress and increased

physiological requirements after HS and resuscitation.
Intravenous NAD+ effectively increased the NAD metabolome, reduced oxidative stress and inflammation, and increased expression of longevity genes safely in elderly humans
Authors: BRAIDY Nady
Published: January 2020

Nicotinamide adenine dinucleotide (NAD+) serves important roles in hydrogen transfer and as the cosubstrate for poly(ADP-ribose) polymerase (PARPs), the sirtuin (SIRT1-7) family of enzymes, and CD38 glycohydrolases. Recently, intravenous (IV) NAD+ therapy has been used as a holistic approach to treat withdrawal from addiction, overcome anxiety and depression, and improve overall quality of life with minimal symptoms between 3-7 days of treatment. We evaluated repeat dose IV NAD+ (1000 mg) for 6 days in a population of 8 healthy adults between the ages of 70 and 80 years. Our data is the first to show that IV NAD+ increases the blood NAD+ metabolome in elderly humans. We found increased concentrations of glutathione peroxidase -3 and paraoxonase-1, anddecreased concentrations of 8-iso-prostaglandin F2α, advanced oxidative protein products, protein carbonyl, C-reactive protein and interleukin 6. We report significant increases in mRNA expression and activity of SIRT1, and Forkhead box O1, and reduced acetylated p53 in peripheral blood mononuclear cells isolated from these subjects. No major adverse effects were reported in this study. The study shows that repeat IV dose of NAD+ is a safe and efficient way to slow down age-related decline in NAD+.
Involvement of Thermo TRP channels on chemothrepeutic agents-induced peripheral pain
Authors: YILDIRIM Mustafa Kemal
Published: January 2020

Accumulating evidences have indicated that disturbances in intracellular free calcium ([Ca2+]i) concentration play an important role in the pathophysiology of peripheral pain. Ca2+ passes cell membrane via different channels such as chemical and voltage gated channels. Apart from the well-known cation channels, there is recently discovered channels namely transient receptor potential (TRP) family. At least, 11 TRP channels in mammalian cells have been identified as thermosensitive TRP (thermo-TRP) channels (Uchida et al. 2017). Two TRP channels (TRPV1 and TRPV2) are activated by high temperatures. Five TRP channels (TRPV1-4 and TRPM2) are activated by different heat temperatures, although two of TRP channels (TRPA1 and TRPM8) are activated by cold and cool temperatures, respectively (Nazıroğlu and Braidy, 2017). It is well known that increase of [Ca2+]i concentration but decrease of intracellular Mg2+ levels induces activation of nitric oxide synthase (NOS) enzyme. By catalytic activity of NOS, nitric oxide synthetizes in neurons. In turn, it induces pain through production of excitatory amino acids and substance P (Medvedeva et al. 2008). Results of recent studies indicated involvement of chemothrepeutic agents (i.e. cisplatin, oxaliplatin and paclitaxel)-induced mitochondrial oxidative stress through activation of Thermo TRP channels such as TRPA1, TRPV1 and TRPM8, although antioxidants induced protective action on the pain induction through inhibition of the TRP channels in the experimental animals (Materazzi et al. 2012). In the oral presentation, I discussed novel effects of chemotherapeutic agents on the peripheral pain by the regulation of TRP channels. I concluded that the chemotherapeutic agents cause TRP channel activation and oxidative stress, which may lead to the pathology of peripheral pain. Itseems to that the exact relationship between TRP channel activation and chemotherapeutic agents still remain to be determined.
Role of melatonin on oxidative stress in traumatic brain injury
Authors: AKYUVA Yener
Published: January 2020

Oxidative stress occurs in the several physiological processes such as phagocytic activity and mitochondrial membrane functions. Oxidative stress is controlled by several enzymatic and non-enzymatic antioxidants. Traumatic brain injury is one of the most common causes of the mortalities. Secondary events occur after primary events like shearing of nerve cells and blood vessels, cause posttraumatic neurodegenerations with an increase in ROS and ROSmediated lipid peroxidation. Melatonin is a member of non-enzymatic antioxidant group. The protective effects of melatonin on traumatic brain injury have been shown in vivo and in vitro studies (Barlow et al. 2018). Also melatonin has been shown to counteract oxidative stress-induced pathophysiologic conditions like ischemia/reperfusion injury, neuronal excitotoxicity and chronic inflammation. Recently, it was reported that TBI-induced oxidative stress in experimental TBI was inhibited by the melatonin treatment (Senol and Nazıroğlu, 2014). In the oral presentation, I will review recent studies on traumatic brain injury in human and rodents. I concluded that the oxidative stress causes changes through activation of second messengers, which may lead to the pathology of TBI, althoughmelatonin has protective effects on the pathology. It seems to that the exact relationship between melatonin and TBI still remain to be determined.
Correlating Transcriptional Networks to Papillary Renal Cell Carcinoma Survival: A Large-Scale Coexpression Analysis and Clinical Validation
Authors: Feng Xingliang , Zhang Meng , Meng Jialin , Wang Yongqiang , Liu Yi , Liang Chaozhao , Fan Song
Published: January 2020

We aimed to investigate the potential mechanisms of progression and identify novel prognosis-related biomarkers for papillary renal cell carcinoma (PRCC) patients. The related data were derived from The Cancer Genome Atlas (TCGA) and then analyzed by weighted gene coexpression network
analysis (WGCNA). The correlation between each module and the clinical traits were analyzed by Pearson’s correlation analysis. Pathway analysis was conducted to reveal potential mechanisms. Hub genes within each module were screened by intramodule analysis, and visualized by Cytoscape
software. Furthermore, important hub genes were validated in an external dataset and clinical samples. A total of 5,839 differentially expressed genes were identified. By using WGCNA, we identified 21 coregulatory gene clusters based on 289 PRCC samples. We found many modules were significantly
associated with clinicopathological characteristics. The gray, pink, light yellow, and salmon modules served as prognosis indicators for PRCC patients. Pathway enrichment analyses found that the hub genes were significantly enriched in the cancer-related pathways. With the external Gene Expression
Omnibus (GEO) validation dataset, we found that PCDH12, GPR4, and KIF18A in the pink and yellow modules were continually associated with the survival status of PRCC, and their expressions were positively correlated with pathological grade. Notably, we randomly chose PCDH12 for validation,
and the results suggested that the PRCC patients with higher pathological grades (II + III) mostly had higher PCDH12 protein expression levels compared with those patients in grade I. These validated hub genes play critical roles in the prognosis prediction of PRCC and serve
as potential biomarkers for future personalized treatment.
Testing Destination Image Scale Invariance For Intergroup Comparison
Authors: Ceylan Demet , Çizel Beykan , KarakaŞ Hatice
Published: January 2020

In destination image studies, researchers often compare individuals and groups with measurement scales. Classical Test Theory (CTT) assumes, when comparing groups, that the scale measures the same social psychological construct in all groups. The assurance of measurement invariance
is a prerequisite for meaningful comparisons across groups. This article reviews theoretical and methodological issues regarding measurement invariance within the framework of confirmatory factor analysis, and aims to test the measurement invariance of the destination image scale by nationality
and gender. Confirmatory factor analysis assures that scores obtained from a destination image measurement model can be generalized for three nationalities and gender groups. In this respect, the results of the survey provide evidence that the scale can deliver valid and reliable measurements
in determining the characteristics of British, German, and Russian tourists without gender bias. Invariance test assures the measurement model to be invariant for both females and males and therefore it is appropriate to compare the results across genders. The findings of this research and
analysis methods used provide valuable insights to destination image literature and cast light on the path for future researchers.
Residents' Support for Tourism Development In a Portuguese Historic Town
Authors: Rodrigues Ana Paula , Vieira Isabel , Fernandes Didiana , Pires Carlos
Published: January 2020

This study depicts some antecedents of residents' support for tourism development (STD) underlying the importance of residents' trust in government actors involved in tourism planning and development in the context of historic towns. The study proposes a conceptual framework that explores
the relationships between community attachment, local government management of tourism, perceived tourism impacts, trust in government actors, and STD. Data collection was carried out by personal survey applied to 150 residents of the small historic town of Lamego, located within the Portuguese
Douro Valley World Heritage Site. Structural equation modeling method was employed to analyze the proposed model. Results suggest that residents' trust in government actors had a significant effect on STD. Residents' perceptions of the tourism benefits positively influenced their STD, and
residents' perceptions of the tourism costs negatively affected their STD. The results support the relationship between community attachment and trust in government actors. Also, community attachment significantly and positively influenced tourism benefits. Perceived effective local government
management of tourism had a strong significant effect on the residents' trust in government actors. Moreover, residents' perceived effective local government management of tourism was a significant determinant of perceived tourism benefits, but did not significantly predict perceived tourism
costs.
One Day Service dalam Isbat Nikah Terpadu Bagi Penduduk Marjinal di Kecamatan Paliyan Tahun 2015 - 2019
Authors: Mustamil Sabit Mustamil
Published: January 2020

Penelitian ini bertujuan untuk mendeskripsikan faktor-faktor yang menyebabkan pernikahan tidak tercatat, peran penghulu dalam menyelesaikan pernikahan yang tidak tercatat, dan solusi hukum atas pernikahan yang tidak tercatat di sebagian masyarakat Kecamatan Paliyan. Metode penelitian yang digunakan adalah deskriptif kualitatif. Penggalian data dilakukan dengan wawancara, dokumentasi dan observasi di  desa yang menjadi tempat pelaksanaan one day service dalam isbat nikah terpadu bagi penduduk marjinal di Kecamatan Paliyan. Adapun yang menjadi informan dalam penelitian ini adalah pegawai KUA, PA, Dukcapil, Kasi Pelayanan Desa, Pendamping Keluarga Harapan (PKH), dan Dukuh  serta peserta one day service dalam isbat nikah bagi pennduduk marjinal di Kecamatan Paliyan. Hasil  penelitian menunjukkan  bahwa  belo nikah, kerubuhan gunung, lokasi yang jauh dan berbukit, kesadaran masyarakat rendah dan kurangnya pengawasan merupakan faktor-faktor yang menyebabkan pernikahan tidak tercatat.

Kata kunci: pernikahan, isbat nikah, dan one day service

 

Abstrct

This study aims to describe the factors that cause unregistered marriages, the role of princes in completing unregistered marriages, and legal solutions to unregistered marriages in some communities in the Paliyan District. The research method used is descriptive qualitative. Data mining was carried out by interviewing, documenting and observing in the village where one day service was carried out in an integrated marriage for marginal residents in the Paliyan District. As for the informants in this study were employees of KUA, PA, Dukcapil, Head of Village Services, Hope Family Assistance (PKH), and Hamlet as well as one day service participants in marriage isbat for marginalized residents in Paliyan District. The results showed that marriage belo, mountain collapse, distant and hilly locations, low public awareness and lack of supervision are factors that cause unregistered marriages.

Keywords: marriage, marriage determination, and one day service
Moderasi Layanan Nikah di KUA Kecamatan Kumun Debai
Authors: Hidayat Natardi
Published: January 2020

Permasalahan yang disorot adalah peran Penghulu mewujudkan moderasi untuk kebersamaan umat guna meningkatkan layanan nikah di KUA Kec. Kumun Debai. Tujuan dilaksanakannya penelitian ini adalah untuk mengetahui peran Penghulu mewujudkan moderasi untuk kebersamaan umat guna meningkatkan layanan nikah di KUA Kec. Kumun Debai. Sedangkan kegunaam penelitian ini adalah untuk memberikan masukan kepada peagawai KUA Kecamatan tentang cara mewujudkan moderasi untuk kebersamaan umat guna untuk meningkatkan layanan nikah. Jenis penelitian ini adalah penelitian lapangan (field research). Penelitian ini bersifat deskriptif eksplorartif (menggali). Fokus penelitian ini adalah berusaha untuk mendeskripsikan, membahas dan menggali gagasan pokok, yaitu moderasi layanan nikah. Sehingga diharapkan terwujudnya layanan nikah yang berorientasi pada moderasi untuk kebersamaan umat yang didukung oleh regulasi yang kuat, fasilitas yang memadai, pemahaman masyarakat yang tinggi, kerjasama lintas sekotral yang baik, kemampuan Penghulu yang mumpuni dan adanya pemberdayaan Penghulu yang kontinyu.

Kata Kunci: Peran Penghulu, Moderasi, Layanan Nikah

 

Abstract

The highligted problem is how role of mariagge registrar attedants embodies moderation for ummah togetherness to improve marital services at Religius Affairs Office of Kumun Debai subdistrict. The purpose of the research is to find out the role of the mariagge registrar attendant i n creating moderation for ummah togetherness in order to improve marital services. This is a field research that is conducted by using qualitative explorative approach. The focus of the research is to describle, discuss and explore the main idea, namely the mederation of marital services. This is a field research that is conducted by using qualitative explorative apporach. The focus of research is to describe. Discuss and explore the main  idea, namely the moderation of marital services. So that the realization of a marriage service orinted to moderation for ummah togetherness must be suported by a strong regulation, adequate facilities, high community understanding, good cross-sectoral cooperation, qualified marriage registrar attendant and the continuous empowerment and upgrading of the marriage registrar attendant.

Keywords: The Role of the Marriage Registrar, Moderation, Marriage Services
Hubungan Antara Anemia Dan Usia Ibu Terhadap Kejadian Bayi Berat Lahir Rendah Di RSUD Labuang Baji Makassar 2019
Authors: Putri Susanto Yoan , Darto Junanti
Published: January 2020

Berdasarkan data yang diperoleh dari Rekam Medik RSUD Labuang Baji Makassar, pada tahun 2017 terdapat 445 bayi yang lahir, pada tahun 2018 terdapat 337 bayi yang lahir dan pada tahun 2019 dari periode Januari sampai dengan Maret terdapat 120 bayi yang lahirl. Tujuan dilakukannya penelitian ini adalah untuk mengetahui hubungan anemia dan usia pada ibu terhadap kejadian BBLR di RSUD Labung Baji Makassar Tahun 2019. Penelitian ini menggunakan metode analitik dengan pendekatan Cross Sectional Study untuk mengetahui hubungan anemia dan usia ibu terhadap kejadian BBLR di RSUD Labuang Baji Makassar tahun 2019 dengan jumlah populasi adalah dari keseluruhan bayi yang lahir pada bulan Januari sampai dengan Maret 2019 di RSUD Labunag Baji Makassar sebanyak 120  bayi dengan besar  sampel yang di ambil sebanyak 120 dengan menggunakan tekhnik total sampilng. Responden yang mengalami anemia terdiagnosa sebanyak 28 orang (23,3%) dan yang memiliki usia yang beresiko sebanyak 39 orang (32,5%). Dari hasil uji statistik dengan menggunakan uji Chi-Square diperoleh variabel anemia dengan  niali p (0,130) > nilai α (0,05). Maka Ho diterima dan Ha di tolak, dan variabel usia  Setelah dianalisis dengan menggunakan uji statistik Chi-square diperoleh niali p (0,013) < nilai α (0,05). Kesimpulan dari kedua variabel yaitu paritas dan umur, tidak terdapat hubungan anemia terhadap kejadian BBLR dan terdapat hubungan usia terhadap kejadian BBLR di RSUD Labunag Baji Makassar 2019
Faktor Yang Berhubungan Terhadap Kejadian Hyperemesis Gravidarum di RS AL Jala Ammari Makassar Tahun 2019
Authors: Amir Fatmawati , Harun Basmalah , Maharani Raisah , Angreini Dwi
Published: January 2020

Berdasarkan data yang diperoleh dari rekam medik RS Jala Amari Makassar,  pada tahun 2016 jumlah ibu hamil sebanyak 274 dengan kejadian Hyperemesis gravidarum sebanyak 51, pada tahun 2017  sebanyak 280 dengan kejadian Hyperemesis gravidarum sebanyak 67,  pada tahun 2018  sebanyak 296 dengan kejadian Hyperemesis gravidarum sebanyak 79, dan pada bulan Januari sampai Mei tahun 2019 sebanyak 143 ibu hamil dengan kejadian Hyperemesis gravidarum sebanyak 22 kejadian. Tujuan dilakukannya penelitian ini adalah untuk mengetahui hubungan antara pekerjaan, gestasi, usia ibu dan paritas ibu terhadap kejadian hyperemesis gravidarum di RS AL Jala Ammari Makassar Tahun 2019. Penelitian ini menggunakan metode penelitian dengan menggunakan pendekatan Cross Sectional Study  untuk mengetahui factor berhubungan terhadap kejadian hyperemesis gravidarum  Populasi dan sampel dalam penelitian ini adalah semua ibu hamil pada bulan Januari sampai Mei 2019 di RS AL Jala Ammari Makassar sebanyak  143 orang,  Dari hasil uji statistic dengan menggunakan uji Chi-Square (Fisher’s Exact Test) diperoleh untuk variabel pekerjaan ibu diperoleh nilai p (0,90) < ɑ (0,05), artinya tidak ada hubungan antara pekerjaan ibu dengan kejadian hyperemesis gravidarum , variabel gestasi diperoleh nilaip p (0,65) <ɑ (0,05), artinya tidak ada hubungan antara gestasi dengan hyperemesis gravidarum , variabel usia ibu diperoleh nilai p (0,004) <ɑ (0,05), artinya ada hubungan antara usia ibu dengan kejadian hyperemesis gravidarum , dan untuk  variabel paritas diperoleh nilai p (0,982) >ɑ (0,05),artinya tidak ada hubungan paritas dengan kejadian hyperemesis gravidarum. Kesimpulan dari variabel pekerjaan, gestasi dan paritas yaitu tidak ada hubungan dengan kejadian hyperemesis gravidarum di RS AL Jala Ammari Makassar dan variabel usia ibu ada hubungan dengan kejadian hyperemesis gravidarum sehingga diharapkan kepada ibu hamil rutin untuk memeriksakan kehamilannya demi mencegah secara dini terjadinya hyperemesis gravidarum serta bagi peneliti berikutnya mmencari variable lain yang diduga menjadi penyebab terjadinya hyperemesis gravidarum.
Schamberg Disease / Progressive Purpuric Dermatosis - Diagnosis and Management Challenges
Authors: Stoica Loredana Elena , Vilcea Alina Maria , Dascalu Rucsandra Cristina , Ciurea Raluca Niculina , Diaconu radu
Published: January 2020

Schamberg disease, also called progressive pigmented purpuric dermatitis is a rare disease characterized by pigmentary, non-palpable, progressive lesions with symmetrical distribution on lower extremities with vasculitic appearance. The etiology of this disease is unknown. Schamberg disease is still considered idiopathic, without an established therapy. Given the fact that this disease has many recurrences, management and treatment is a challenge for the dermatologist.
Revealing the CO X-factor in Dark Molecular Gas through Sensitive ALMA Absorption Observations
Authors: Luo Gan , Li Di , Tang Ningyu , Dawson J. R. , Dickey John M. , Bronfman L. , Qin Sheng-Li , Gibson Steven J. , Plambeck Richard , Finger Ricardo , Green Anne , Mardones Diego , Koo Bon-Chul , Lo Nadia
Published: January 2020

Carbon-bearing molecules, particularly CO, have been widely used as tracers of molecular gas in the interstellar medium (ISM). In this work, we aim to study the properties of molecules in diffuse, cold environments, where CO tends to be underabundant and/or subthermally excited. We performed one of the most sensitive (down to

τ

rms

CO

∼
0.002

and

τ

rms

HCO

+

∼
0.0008

) submillimeter molecular absorption line observations toward 13 continuum sources with the ALMA. CO absorption was detected in diffuse ISM down to

A

v

<
0.32

mag

and HCO+ was detected down to

A

v

<
0.2

mag

, where atomic gas and dark molecular gas start to dominate. Multiple transitions measured in absorption toward 3C454.3 allow for a direct determination of excitation temperatures T
ex of 4.1 and 2.7 K, for CO and for HCO+, respectively, which are close to the cosmic microwave background and explain their being undercounted in emission surveys. A stronger linear correlation was found between

N

HCO

+

and

N

H

2

(Pearson correlation coefficient P ∼ 0.93) than that of N
CO and

N

H

2

(P ∼ 0.33), suggesting HCO+ is a better tracer of H2 than CO in diffuse gas. The derived CO-to-H2 conversion factor (the CO X-factor) of (14 ± 3) × 1020 cm−2 (K

km

s

−
1

)−1 is approximately six times larger than the average value found in the Milky Way.
THE DEALS AND THE REALITY OF CZECH POSTMODERN WAR VETERANS
Authors: Laštovková Jitka , Brnula Peter , Novotný Lukáš
Published: January 2020

The paper broaches the topic of the perception of the care and attention that the state affords to postmodern war veterans. The analysis is based on a qualitative paradigm and the authors work with semi-structured interviews with 12 veterans who were in international military operations and who are no longer on active duty. In the context of the relative deprivation theory, the paper shifts from the topic of one's own perception of identity in comparison to other veterans to the reassessment of the past and the related impact. At the end of the paper, the authors focus the discussion on the need for better care to be taken of this group.
A fortuitous find: a unique haplotype of Ooencyrtus nezarae Ishii (Encyrtidae: Encyrtinae) discovered in Florida
Authors: Goltz Nicholas , Awad Jessica , Moore Matthew , Talamas Elijah
Published: January 2020

The adventive arrival of biological control agents circumvents the regulatory process by introducing exotic species to control invasive pests and is generally followed by post hoc risk evaluation. The bean plataspid,Megacopta cribraria(Fabricius) (Hemiptera: Plataspidae), is an invasive pest of leguminous crops in the south-eastern United States that was eventually followed by two parasitoid wasps from its range in the eastern hemisphere,Paratelenomus saccharalis(Dodd) (Scelionidae) andOoencyrtus nezaraeIshii (Encyrtidae). In North Central Florida, sentinel egg masses, intended to captureParatelenomus saccharalis, instead yieldedOoencyrtus nezarae, which was previously known only from Alabama (Ademokoya et al. 2018). Two generations ofO. nezaraewere subsequently reared in the laboratory. COI sequences from the Florida population ofO. nezaraediffered by 1.3% from the Alabama population and the presence of a different haplotype suggests the possibility of a separate introduction. Laboratory parasitism rates, sex ratios, morphology, molecular diagnosis and implications for agriculture are discussed.
Notes on the predation of an assassin bug by a spider in a Neotropical cave
Authors: Bernardi Leopoldo Ferreira de Oliveira , Sperandei Vinícius da Fontoura , Audino Lívia Dorneles , Sena Carlos Henrique , Alves Jessica Aline
Published: January 2020

Intraguild predation have rarely been documented in scientific literature, even though this type of interaction can affect population dynamics and competition. In this study we present an intraguild predation event that occurred at different times, but in the same cave, where we observed spiders of the speciesEnoploctenus cyclotoraxpreying on specimens of assassin bugZelurus diasi. Inside the studied caves, food resources are scarce and populations can be fairly small in size. It is possible, therefore, that these events are the result of ecological pressures imposed by the hypogean environment.
Cafés sans alcool à Paris : œuvre de tempérance par et pour des étrangers à la fin du XIX e siècle
Authors: Afanasyeva Victoria
Published: January 2020

En 1889, les visiteurs et les visiteuses de l’Exposition universelle à Paris découvrent, au sein de la section de l’économie sociale, un nouveau concept de débit de boissons : un café populaire de tempérance. Présenté et mis en place par les membres de l’Union chrétienne mondiale des femmes pour la tempérance, l’œuvre s’avère inadaptée au contexte antialcoolique français. Seule Miss de Broen, une bienfaitrice anglaise, décide d’imiter l’exemple de l’Exposition, et ouvre un établissement de tempérance dans un quartier touristique de Paris.
Les radioisotopes, une solution à la problématique agricole ouest-africaine (1964-1971)
Authors: Gecit Jean
Published: January 2020

L’utilisation des radioisotopes a vocation à se généraliser en Afrique de l’Ouest, dans les années 1960, afin de faire face à la délicate problématique agricole. Elle permet des économies en eau, en intrants, et œuvre à la conservation des denrées alimentaires en irradiant les cultures et en écartant les éléments nuisibles. Les Nations unies, ses agences spécialisées et la France interviennent directement en Afrique de l’Ouest et mettent en lumière des possibilités applicables à l’échelle mondiale.
Gastronomie coréenne, élément des relations internationales
Authors: Yeong Han Jae
Published: January 2020

La cuisine gastronomique coréenne, élément clé de l’identité nationale, a été revisitée après les Jeux olympiques de Séoul en 1988, à la suite desquels le kimchi , emblème du patrimoine culinaire coréen, a connu une diffusion mondiale. La cuisine, connue comme la «  K-Food  » dans la « vague coréenne », est considérée comme l’un des éléments du «  soft power  » dans la diplomatie sud-coréenne et la tradition culinaire coréenne est sauvegardée au niveau international par l’UNESCO.
Le chocolat, une étrange passion suisse
Authors: Fumey Gilles
Published: January 2020

Comment la Suisse qui n’a pas de colonie tropicale le fournissant en chocolat a-t-elle pu devenir l’une des plus prestigieuses références culturelles du chocolat ? Sans société curiale ni corporation pâtissière dédiée au chocolat, ce petit pays alpin a transformé la culture du chocolat entre le moment où elle l’a reçue de l’Italie à la fin du xviii e  siècle et la Première Guerre mondiale où l’industrie du chocolat tournait à plein régime. De la passion artisanale de quelques familles à l’adoption par la nation suisse du chocolat, le chemin passe par les villes, leurs confiseries et tout un écosystème symbolique que le protestantisme porte à son excellence.
Du maître queux au cuisinier du XIX e siècle : la construction de la figure du chef à travers la carrière de Marie-Antoine Carême
Authors: Godfroy-Tayart de Borms Marion
Published: January 2020

On écrit souvent que Marie-Antoine Carême est une figure fondatrice pour l’histoire des chefs. L’affirmation pose cependant question. Il convient d’interroger les conditions d’apparition de sa figure, les critères de définition de son expérience professionnelle et de les inscrire dans les enjeux propres au xix e  siècle d’une nouvelle construction politique et sociale européenne. Dès lors, en croisant les critères de définitions professionnels et les mutations socioéconomiques, un modèle apparaît qui lie la condition de son exercice à celui des pratiques d’une élite.
Le mythe de la cuisine viennoise
Authors: Horel Catherine
Published: January 2020

Les produits alimentaires et la gastronomie ont circulé dans l’Empire, constituant un lieu de mémoire de la cuisine habsbourgeoise. Les fonctionnaires, militaires, enseignants ont vu leurs goûts changer au gré de leurs mutations : leurs femmes ne devaient pas seulement s’adapter à la langue de leur cuisinière, mais aussi à ses pratiques et aux ingrédients du marché local. Les livres de cuisine à leur disposition concentraient la diversité de la cuisine de la monarchie. Le vocabulaire reflète ces transferts au travers de mots qui sont des créations transnationales.
Une histoire de l’usager des technologies de l’information et de la communication (TIC)
Authors: Méadel Cécile
Published: January 2020

Que peut-on dire sur l’usager des technologies de l’information et de la communication qui vaille à la fois pour les différentes technologies domestiques concernées et pour les cent dernières années ? Cette période voit en effet à la fois des innovations permanentes, la démultiplication des outils, leur transformation incessante et leur diffusion accélérée dans toutes les strates de la population. Cet article propose, à partir d’une relecture des recherches sur la situation française, de comprendre comment l’individu se redéfinit et redéfinit son réseau social à travers leur utilisation. Après avoir présenté quelques caractéristiques propres aux usagers, l’article se développe autour d’une double tension qui fait controverse dans les travaux : la première entre usager pionnier et usager de masse, la seconde entre usager individuel et usager collectif.
Le parfait wikipédien. Réglementation de l’écriture et engagement des novices dans un commun de la connaissance (2000-2018)
Authors: Joubert Léo
Published: January 2020

Les sciences sociales sont parvenues à un consensus sur le fait qu’il n’y a de commun ou de bien commun qu’encadré par des règles consensuelles entre participants. Comment des participants à Wikipédia, qui est un « commun de la connaissance », ont-ils permis l’application des règles en instaurant une surveillance des contributions (des autres). Nous formons l’hypothèse qu’un surveillant est légitime s’il préserve autant la possibilité d’engagement des novices qu’un état jugé consensuel de la réglementation du wiki. Trois périodes sont mises en valeur à l’aide d’indicateurs correspondant à l’évolution de la version française de Wikipédia. Durant sa genèse, de 2000 à 2004, les premiers contributeurs écrivent les règles constitutives. Entre 2004 et 2008, un flux gigantesque de novices oblige les surveillants à s’adapter en précisant les règles et en développant des robots pour gérer la charge de travail. Depuis 2008, de nouveaux dispositifs de surveillance en temps réel apparaissent. Sous la pression de surveillants chevronnés, les règles se transforment en mode d’emploi. Parce qu’aider à devenir un bon contributeur revient à prescrire un comportement légitime, la réglementation renforcée devient compatible avec la surveillance. Au cours de ces trois périodes, la « dialectique de l’engagement et de la réglementation » permet d’appréhender la légitimité de la surveillance au sein d’un commun de la connaissance.
1981 : une recomposition syndicale dans l’audiovisuel et le cinéma
Authors: Zarka Samuel
Published: January 2020

L’année 1981 est marquée par un « conflit aigu » entre la direction du syndicat CGT de la production cinématographique et de télévision (SNTPCT-CGT) et une partie des syndiqués. La crise aboutit à scinder le fait syndical technicien en deux organisations distinctes, l’une restant au sein de la Fédération du spectacle, l’autre la quittant, ce qui modifie pour longtemps la configuration de la négociation collective dans les activités concernées. Les travaux évoquant cet épisode font généralement prévaloir le « corporatisme » de la direction du syndicat, sans qu’on connaisse précisément les tenants et aboutissants du conflit. À la lumière d’archives syndicales pour partie inédites de la Fédération nationale du spectacle et d’entretiens avec des responsables syndicaux, acteurs ou témoins des événements, on voit émerger, à côté des équipes de cinéma, de nouvelles équipes, très proches par leurs modalités d’engagement discontinu et leurs techniques de travail : les techniciens de l’audiovisuel. La genèse de ces équipes pose dès lors la question suivante : les dispositions juridiques de référence, applicables aux équipes de cinéma, doivent-elles être élargies à l’audiovisuel, où les normes salariales sont plus défavorables ? Cette question traduit une problématique typique de redéfinition des périmètres professionnels, interrogeant la notion même de qualification professionnelle. Dans une perspective socio-historique, nous visons à mieux comprendre la recomposition du dispositif de production, de diffusion et de consommation ciné-audiovisuelle en France, dans la période qui succède à l’hégémonie de l’ORTF.
Épreuves professionnelles et engagement collectif dans la presse en ligne à Moscou (2012-2019)
Authors: Daucé Françoise
Published: January 2020

Dans la Russie des années 2010, le regain d’intérêt pour le syndicalisme dans les médias indépendants fait figure d’énigme tant le modèle syndical a été marginalisé après la chute de l’URSS et tant les emprises politiques pesant sur les mouvements alternatifs semblent défavorables à l’émergence d’organisations syndicales. Comment agir collectivement dans ce contexte ? L’exemple de la création d’un Syndicat indépendant des journalistes en 2016 permet de réfléchir aux épreuves politiques et professionnelles qui suscitent un intérêt renouvelé pour l’action collective. En Russie, les journalistes appartenant aux médias libéraux, notamment numériques, font face à des difficultés qui associent emprises politiques et fragilité salariale. Les conflits éditoriaux dans les rédactions s’accompagnent généralement de licenciements, démissions et réembauches. Dans ce contexte, l’intérêt pour le syndicalisme ressurgit, afin de répondre aux défis posés par des carrières professionnelles sous contrainte politique.
Musique et télévision en France, d’hier à aujourd’hui
Authors: Briont Théo
Published: January 2020

L’extension du domaine de la musique (classique et contemporaine), des salles, du disque, de la radio à la télévision, pose des questions de programmation, de compétences musicales, d’orchestres, de moyens techniques et de production, ainsi que de rapports avec les différents milieux de la musique, dont bien entendu les créateurs, et avec les publics. Un mariage de raison s’établit progressivement. C’est du reste le cas pour d’autres genres musicaux. Des hommes et des femmes se distinguent peu à peu par leur capacité à plaider la cause de la musique à l’intérieur des chaînes comme devant les téléspectateurs. La place accrue des critères d’audience tend à renvoyer les captations de concerts comme les créations à des heures tardives sur la majorité des chaînes, tandis que se développent les marchés des cassettes, de la vidéo, puis des DVD. Mais cette même musique retrouve une partie de la place perdue sur le petit écran grâce au streaming et à la constitution de chaînes en ligne. On s’interroge enfin – par rapport à des expériences étrangères – sur la place de la télévision dans la culture musicale et sur la transformation de la mission de culture à laquelle l’État fait souscrire les chaînes.
Un parcours historien en des temps numériques
Authors: Rygiel Philippe
Published: January 2020

Les travaux empiriques étant peu nombreux encore, les discours historiens consacrés aux mutations que connaît la discipline historique prise dans le contexte du déploiement des transformations numériques portent fortement la marque des circonstances de leur énonciation. C’est donc après le rappel des traits saillants d’un parcours d’historien confronté au numérique que l’auteur revient sur les enjeux lui apparaissant aujourd’hui centraux, en particulier la formation des futurs historiens, les conditions nouvelles d’une réflexion sur le mode de production des connaissances historiques et le régime des sources de l’histoire des temps numériques.
Les droits de l’homme au cœur du débat politique
Authors: Mertens Pierre
Published: January 2020

Le droit international reconnaît le principe de la souveraineté nationale et consacre son corollaire obligé : le principe de non-intervention. Les droits fondamentaux de l’homme ne font cependant pas partie de ce "domaine réservé". Il s’agit de la conséquence ultime de leur "internationalisation". Ils détiennent une portée d’ordre public international et ont valeur de jus cogens . On pourrait établir un "common core" des droits essentiels, auxquels il ne pourrait être porté atteinte en aucune circonstance. Dans la pratique, le dogme de la "sécurité nationale" – même en démocratie, est souvent invoqué pour faire échec à ceux-ci. Ces droits de l’homme se situent au cœur des rapports entre l’individu et l’Etat, entre la personne et le pouvoir, entre l’homme et la société, donc ils s’insèrent "au vif du sujet" politique par excellence.
Essai sur la crise de légitimation et sur la naissance de la société moderne dans le "Léviathan" de Thomas Hobbes
Authors: Rigaux Marie-Françoise
Published: January 2020

Soucieux de comprendre et de caractériser la naissance des sociétés modernes, Jürgen Habermas a démontré que la nature du rapport qu’entretient le couple travail/interaction s’avère déterminante dans l’explication du passage d’une société de type traditionnel à une société "rationnelle". Après avoir rappelé les principaux éléments de la thèse de Habermas, l’auteur de cet article se propose de l’illustrer à l’aide de quelques observations tirées de la lecture du "Léviathan" de Thomas Hobbes. Elle montrera ainsi que le penseur anglais est l’un des premiers à inscrire la philosophie politique dans le mouvement de rationalisation économique et sociale qui affecte la société anglaise du 17e siècle. Son analyse de la société, comme ses considérations à propos de la justice, contribuent à l’édification d’un système de légitimation sécularisé ; ceci autorise le juriste et le philosophe du 20e siècle à retrouver dans l’œuvre de Thomas Hobbes les prémisses de la construction théorique de ce que, plus tard, on appellera l’Etat abstrait.