bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figures 1-10 from Cancer Cell Secretion of the DAMP Protein HMGB1 Supports Progression in Malignant Mesothelioma
Authors: Jube Sandro , Rivera Zeyana S. , Bianchi Marco E. , Powers Amy , Wang Ena , Pagano Ian , Pass Harvey I. , Gaudino Giovanni , Carbone Michele , Yang Haining
Published: April 2023

PDF file - 4.5MB, Figure S1. HMGB1 inhibitors hinder asbestos-induced HM transformation. Figure S2. Expressions of the HMGB1 receptors TLR2 and TLR4 are variable in MM cells. Figure S3. HMGB1 is a chemotactic and mitogenic factor in MM cells. Figure S4. Secreted HMGB1 is an autocrine chemotactic factor in MM cells. Figure S5. HMGB1 inhibition has no effect on the survival and migration of MM cells that are low HMGB1 producers (PPM-Mill). Figure S6. HMGB1 inhibition does not induce cell death in HM. Figure S7. Inhibition of HMGB1 induces apoptosis in MM cells "addicted" to HMGB1. Figure S8. HMGB1 supports the invasive phenotype in MM cells. Figure S9. Gene expression analysis of REN cells treated with HMGB1.
Supplementary Table 2 from 53BP1 Is a Haploinsufficient Tumor Suppressor and Protects Cells from Radiation Response in Glioma
Authors: Squatrito Massimo , Vanoli Fabio , Schultz Nikolaus , Jasin Maria , Holland Eric C.
Published: April 2023

XLS file - 66K, Co-occurrence of TP53BP1 and TP53 alterations in the TCGA dataset for GBM
Supplementary Materials and Methods from MEK Inhibition Leads to PI3K/AKT Activation by Relieving a Negative Feedback on ERBB Receptors
Authors: Turke Alexa B. , Song Youngchul , Costa Carlotta , Cook Rebecca , Arteaga Carlos L. , Asara John M. , Engelman Jeffrey A.
Published: April 2023

PDF file - 104K, Supplemental Materials and Methods include additional materials and methods and supporting references, and provides more detailed explanation of cell lines and cell culture reagents, antibodies, shRNA haripin constructs, and mass spectrometry protocol.
Supplementary Methods from 53BP1 Is a Haploinsufficient Tumor Suppressor and Protects Cells from Radiation Response in Glioma
Authors: Squatrito Massimo , Vanoli Fabio , Schultz Nikolaus , Jasin Maria , Holland Eric C.
Published: April 2023

PDF file - 132K
Supplementary Figure 5 from 53BP1 Is a Haploinsufficient Tumor Suppressor and Protects Cells from Radiation Response in Glioma
Authors: Squatrito Massimo , Vanoli Fabio , Schultz Nikolaus , Jasin Maria , Holland Eric C.
Published: April 2023

PDF file - 205, 53BP1 modulates NHEJ in glioma cell lines
Supplementary Figure 3 from 53BP1 Is a Haploinsufficient Tumor Suppressor and Protects Cells from Radiation Response in Glioma
Authors: Squatrito Massimo , Vanoli Fabio , Schultz Nikolaus , Jasin Maria , Holland Eric C.
Published: April 2023

PDF file - 22K, 53BP1 silencing does not increase TMZ sensitivity in T98G cells
Supplementary Figure Legends 1-4 from Sphingosine-1-Phosphate Produced by Sphingosine Kinase 1 Promotes Breast Cancer Progression by Stimulating Angiogenesis and Lymphangiogenesis
Authors: Nagahashi Masayuki , Ramachandran Subramaniam , Kim Eugene Y. , Allegood Jeremy C. , Rashid Omar M. , Yamada Akimitsu , Zhao Renping , Milstien Sheldon , Zhou Huiping , Spiegel Sarah , Takabe Kazuaki
Published: April 2023

PDF file - 78K
Supplementary Figure 4 from Sphingosine-1-Phosphate Produced by Sphingosine Kinase 1 Promotes Breast Cancer Progression by Stimulating Angiogenesis and Lymphangiogenesis
Authors: Nagahashi Masayuki , Ramachandran Subramaniam , Kim Eugene Y. , Allegood Jeremy C. , Rashid Omar M. , Yamada Akimitsu , Zhao Renping , Milstien Sheldon , Zhou Huiping , Spiegel Sarah , Takabe Kazuaki
Published: April 2023

PDF file - 7.4MB, SK1-I reduces recruitment of macrophages to peritumoral regions. Immunofluorescent staining of macrophages in the peritumoral region with F4/80. LYVE-1+ staining revealed only very little co-staining with F4/80.
Supplementary Figure 3 from Sphingosine-1-Phosphate Produced by Sphingosine Kinase 1 Promotes Breast Cancer Progression by Stimulating Angiogenesis and Lymphangiogenesis
Authors: Nagahashi Masayuki , Ramachandran Subramaniam , Kim Eugene Y. , Allegood Jeremy C. , Rashid Omar M. , Yamada Akimitsu , Zhao Renping , Milstien Sheldon , Zhou Huiping , Spiegel Sarah , Takabe Kazuaki
Published: April 2023

PDF file - 690K, The effect of S1P on expression of VEGF-A and VEGF-C. mRNA was isolated from 4T1-luc2 cells treated with 100 nM of S1P or 0.1% BSA. Expression of VEGF-A and VEGF-C was determined by qPCR and normalized to GAPDH mRNA. Data are expressed as fold increases � S.D.
Supplementary Methods and Materials from Bone-Derived IGF Mediates Crosstalk between Bone and Breast Cancer Cells in Bony Metastases
Authors: Hiraga Toru , Myoui Akira , Hashimoto Nobuyuki , Sasaki Akira , Hata Kenji , Morita Yoshihiro , Yoshikawa Hideki , Rosen Clifford J. , Mundy Gregory R. , Yoneda Toshiyuki
Published: April 2023

Supplementary Methods and Materials from Bone-Derived IGF Mediates Crosstalk between Bone and Breast Cancer Cells in Bony Metastases
Supplementary Figure 2 from Sphingosine-1-Phosphate Produced by Sphingosine Kinase 1 Promotes Breast Cancer Progression by Stimulating Angiogenesis and Lymphangiogenesis
Authors: Nagahashi Masayuki , Ramachandran Subramaniam , Kim Eugene Y. , Allegood Jeremy C. , Rashid Omar M. , Yamada Akimitsu , Zhao Renping , Milstien Sheldon , Zhou Huiping , Spiegel Sarah , Takabe Kazuaki
Published: April 2023

PDF file - 3.7MB, Effect of knockdown of SphK1 on S1P secretion from 4T1-luc2 cells and on in vitro hemangiogenesis and lymphangiogenesis. (A-C) 4T1-luc2 cells were stably transfected with control-shRNA or SphK1-shRNA. (A) Expression of SphK1 was determined by qPCR and normalized to GAPDH mRNA. *, P < 0.001. (B) SphK1 proteins were determined by western blot. (C) S1P in the culture medium from wild type (WT) 4T1-luc2 cells, 4T1-luc2 cells transfected with control-shRNA and SphK1-shRNA were determined by LC-ESI-MS/MS. *, P <0.01. (D, E) HUVECs and HLECs tagged with GFP were cultured on reduced growth factor basement membrane matrix-coated 48 well plates and incubated for 6 hours with culture media from the indicated 4T1-luc2 cells. (D) Representative images. (E) Two random fields per well were photographed. Total tube length was determined and means � SD are shown. *, P <0.05.
Supplementary Figure 1 from Sphingosine-1-Phosphate Produced by Sphingosine Kinase 1 Promotes Breast Cancer Progression by Stimulating Angiogenesis and Lymphangiogenesis
Authors: Nagahashi Masayuki , Ramachandran Subramaniam , Kim Eugene Y. , Allegood Jeremy C. , Rashid Omar M. , Yamada Akimitsu , Zhao Renping , Milstien Sheldon , Zhou Huiping , Spiegel Sarah , Takabe Kazuaki
Published: April 2023

PDF file - 763K, Circulating levels of SK1-I and S1P in plasma from na�ve BALB/c mice. Mice were treated with SK1-I (20 mg/kg) i.p. and plasma samples were taken at the indicated time point (n = 3). The levels of SK1-I (A) and S1P (B) were determined by LC-ESI-MS/MS, and means � SD are shown. *, P < 0.05 as compared to 0 hour time point.
Supplementary Figure 1 Legend from Bone-Derived IGF Mediates Crosstalk between Bone and Breast Cancer Cells in Bony Metastases
Authors: Hiraga Toru , Myoui Akira , Hashimoto Nobuyuki , Sasaki Akira , Hata Kenji , Morita Yoshihiro , Yoshikawa Hideki , Rosen Clifford J. , Mundy Gregory R. , Yoneda Toshiyuki
Published: April 2023

PDF file - 11K
Supplementary Table 5 from Biomarkers of HPV in Head and Neck Squamous Cell Carcinoma
Authors: Liang Caihua , Marsit Carmen J. , McClean Michael D. , Nelson Heather H. , Christensen Brock C. , Haddad Robert I. , Clark John R. , Wein Richard O. , Grillone Gregory A. , Houseman E. Andres , Halec Gordana , Waterboer Tim , Pawlita Michael , Krane Jeffrey F. , Kelsey Karl T.
Published: April 2023

PDF file - 65K, The association between selected markers and overall survival of HNSSC patients with and without adjustment for tumor stages, Eastern Massachusetts, 1999-2003
Supplementary Table 4 from Biomarkers of HPV in Head and Neck Squamous Cell Carcinoma
Authors: Liang Caihua , Marsit Carmen J. , McClean Michael D. , Nelson Heather H. , Christensen Brock C. , Haddad Robert I. , Clark John R. , Wein Richard O. , Grillone Gregory A. , Houseman E. Andres , Halec Gordana , Waterboer Tim , Pawlita Michael , Krane Jeffrey F. , Kelsey Karl T.
Published: April 2023

PDF file - 74K, The association between presence of HPV DNA detected by varying positive thresholds and overall survival of HNSSC patients stratified by tumor sites, Eastern Massachusetts, 1999-2003
Supplementary Table 4 from Multilevel Whole-Genome Analysis Reveals Candidate Biomarkers in Clear Cell Renal Cell Carcinoma
Authors: Girgis Andrew H. , Iakovlev Vladimir V. , Beheshti Ben , Bayani Jane , Squire Jeremy A. , Bui Anna , Mankaruos Marina , Youssef Youssef , Khalil Bishoy , Khella Heba , Pasic Maria , Yousef George M.
Published: April 2023

PDF file - 127K, Significantly expressed genes in regions that are cytogenetically associated with copy-number aberrations in aberrant tumors compared to normal kidney as based by GSEA and integration of protein, miRNA and methylation data
Supplementary Figures 1-3 from Tpx2 Controls Spindle Integrity, Genome Stability, and Tumor Development
Authors: Aguirre-Portolés Cristina , Bird Alexander W. , Hyman Anthony , Cañamero Marta , Pérez de Castro Ignacio , Malumbres Marcos
Published: April 2023

PDF file - 224K, Supplemental data includes three figures with a detailed description of the cell cycle characteristics of Tpx2(+/-) cells, quantification of tubulin staining in Tpx2-null embryonic cells and levels of Tpx2 mRNA levels in different tissues from Tpx2(+/-) mice.
Supplementary Methods from Multilevel Whole-Genome Analysis Reveals Candidate Biomarkers in Clear Cell Renal Cell Carcinoma
Authors: Girgis Andrew H. , Iakovlev Vladimir V. , Beheshti Ben , Bayani Jane , Squire Jeremy A. , Bui Anna , Mankaruos Marina , Youssef Youssef , Khalil Bishoy , Khella Heba , Pasic Maria , Yousef George M.
Published: April 2023

Supplementary Methods from Multilevel Whole-Genome Analysis Reveals Candidate Biomarkers in Clear Cell Renal Cell Carcinoma
Supplementary Table 3 from Temporal Molecular and Biological Assessment of an Erlotinib-Resistant Lung Adenocarcinoma Model Reveals Markers of Tumor Progression and Treatment Response
Authors: Weaver Zoë , Difilippantonio Simone , Carretero Julian , Martin Philip L. , El Meskini Rajaa , Iacovelli Anthony J. , Gumprecht Michelle , Kulaga Alan , Guerin Theresa , Schlomer Jerome , Baran Maureen , Kozlov Serguei , McCann Thomas , Mena Salvador , Al-Shahrour Fatima , Alexander Danny , Wong Kwok-Kin , Van Dyke Terry
Published: April 2023

XLS file - 395K, Identities of all metabolites detected, grouped by class of compound
Supplementary Table 1 from Temporal Molecular and Biological Assessment of an Erlotinib-Resistant Lung Adenocarcinoma Model Reveals Markers of Tumor Progression and Treatment Response
Authors: Weaver Zoë , Difilippantonio Simone , Carretero Julian , Martin Philip L. , El Meskini Rajaa , Iacovelli Anthony J. , Gumprecht Michelle , Kulaga Alan , Guerin Theresa , Schlomer Jerome , Baran Maureen , Kozlov Serguei , McCann Thomas , Mena Salvador , Al-Shahrour Fatima , Alexander Danny , Wong Kwok-Kin , Van Dyke Terry
Published: April 2023

PDF file - 91K, Number of altered biochemicals and directional changes in the tumor induction experiment
Supplementary Figure 1 from Transcription Factor NFATc2 Controls the Emergence of Colon Cancer Associated with IL-6–Dependent Colitis
Authors: Gerlach Katharina , Daniel Carolin , Lehr Hans A. , Nikolaev Alexei , Gerlach Thomas , Atreya Raja , Rose-John Stefan , Neurath Markus F. , Weigmann Benno
Published: April 2023

PDF file - 547K, DSS Colitis
Supplementary Figure 4 from Ectopic ATP Synthase Blockade Suppresses Lung Adenocarcinoma Growth by Activating the Unfolded Protein Response
Authors: Chang Hsin-Yi , Huang Hsuan-Cheng , Huang Tsui-Chin , Yang Pan-Chyr , Wang Yi-Ching , Juan Hsueh-Fen
Published: April 2023

PDF file, 215K, Citreoviridin does not induce apoptosis in CL1-0 or A549 cells.
Supplementary Figure 3 from Ectopic ATP Synthase Blockade Suppresses Lung Adenocarcinoma Growth by Activating the Unfolded Protein Response
Authors: Chang Hsin-Yi , Huang Hsuan-Cheng , Huang Tsui-Chin , Yang Pan-Chyr , Wang Yi-Ching , Juan Hsueh-Fen
Published: April 2023

PDF file, 228K, Protein expression profiles of citreoviridin-treated cells. The protein expression profiles of citreoviridin- (Citreo, lower) treated CL1-0 cells were compared to DMSO- (upper) treated controls on a time-course from 12 to 72 h.
Supplementary Figure 8 from Bioactivity and Prognostic Significance of Growth Differentiation Factor GDF15 Secreted by Bone Marrow Mesenchymal Stem Cells in Multiple Myeloma
Authors: Corre Jill , Labat Elodie , Espagnolle Nicolas , Hébraud Benjamin , Avet-Loiseau Hervé , Roussel Murielle , Huynh Anne , Gadelorge Mélanie , Cordelier Pierre , Klein Bernard , Moreau Philippe , Facon Thierry , Fournié Jean-Jacques , Attal Michel , Bourin Philippe
Published: April 2023

PDF file - 67K, Transfection of BM-MSC with plasmids encoding shRNA targeting GDF15 and co-culture with MOLP-6 cells
Supplementary Figure 6 from Raf Kinase Inhibitor RKIP Inhibits MDA-9/Syntenin-Mediated Metastasis in Melanoma
Authors: Das Swadesh K. , Bhutia Sujit K. , Sokhi Upneet K. , Azab Belal , Su Zhao-zhong , Boukerche Habib , Anwar Talha , Moen Erika L. , Chatterjee Devasis , Pellecchia Maurizio , Sarkar Devanand , Fisher Paul B.
Published: April 2023

PDF file - 622K, Effects of RKIP expression on cell growth
Supplementary Figure 3 from Raf Kinase Inhibitor RKIP Inhibits MDA-9/Syntenin-Mediated Metastasis in Melanoma
Authors: Das Swadesh K. , Bhutia Sujit K. , Sokhi Upneet K. , Azab Belal , Su Zhao-zhong , Boukerche Habib , Anwar Talha , Moen Erika L. , Chatterjee Devasis , Pellecchia Maurizio , Sarkar Devanand , Fisher Paul B.
Published: April 2023

PDF file - 413K, ERK activation negatively regulate RKIP expression
Supplementary Figure 2 from IKK-ϵ Coordinates Invasion and Metastasis of Ovarian Cancer
Authors: Hsu Sarah , Kim Marianne , Hernandez Lidia , Grajales Valentina , Noonan Anne , Anver Miriam , Davidson Ben , Annunziata Christina M.
Published: April 2023

PDF file - 172K, Validation of IKKe gene signature
Supplementary Methods from CD44 Proteolysis Increases CREB Phosphorylation and Sustains Proliferation of Thyroid Cancer Cells
Authors: De Falco Valentina , Tamburrino Anna , Ventre Simona , Castellone Maria Domenica , Malek Mouhannad , Manié Serge N. , Santoro Massimo
Published: April 2023

PDF file - 117K
Supplementary Figure 2 from Interleukin-17 Promotes Formation and Growth of Prostate Adenocarcinoma in Mouse Models
Authors: Zhang Qiuyang , Liu Sen , Ge Dongxia , Zhang Qingsong , Xue Yun , Xiong Zhenggang , Abdel-Mageed Asim B. , Myers Leann , Hill Steven M. , Rowan Brian G. , Sartor Oliver , Melamed Jonathan , Chen Zhenbang , You Zongbing
Published: April 2023

PDF file - 6.6MB, Immunohistochemical staining of laminin in whole prostate sections.
Supplementary Figure 2 from Chromogranin A Regulates Tumor Self-Seeding and Dissemination
Authors: Dondossola Eleonora , Crippa Luca , Colombo Barbara , Ferrero Elisabetta , Corti Angelo
Published: April 2023

PDF file - 116K
Supplementary Methods, Figure Legends 1-6 from Radiotherapy Increases the Permissiveness of Established Mammary Tumors to Rejection by Immunomodulatory Antibodies
Authors: Verbrugge Inge , Hagekyriakou Jim , Sharp Leslie L. , Galli Mara , West Alison , McLaughlin Nicole M. , Duret Hélène , Yagita Hideo , Johnstone Ricky W. , Smyth Mark J. , Haynes Nicole M.
Published: April 2023

PDF file - 119K, Detailed description of the Supplementary Materials and Methods, Experimental 4T1.2 in vivo Data and Figure Legends
Supplementary Figure 1 from Chromogranin A Regulates Tumor Self-Seeding and Dissemination
Authors: Dondossola Eleonora , Crippa Luca , Colombo Barbara , Ferrero Elisabetta , Corti Angelo
Published: April 2023

PDF file - 161K
Supplementary Figure 5 from Radiotherapy Increases the Permissiveness of Established Mammary Tumors to Rejection by Immunomodulatory Antibodies
Authors: Verbrugge Inge , Hagekyriakou Jim , Sharp Leslie L. , Galli Mara , West Alison , McLaughlin Nicole M. , Duret Hélène , Yagita Hideo , Johnstone Ricky W. , Smyth Mark J. , Haynes Nicole M.
Published: April 2023

PDF file - 282K, Analysis of the combined therapeutic effects of radiotherapy and alpha-CD137/alpha-PD-1 therapy in established 4T1.2 tumors
Supplementary Methods from Nanocytology of Rectal Colonocytes to Assess Risk of Colon Cancer Based on Field Cancerization
Authors: Damania Dhwanil , Roy Hemant K. , Subramanian Hariharan , Weinberg David S. , Rex Douglas K. , Goldberg Michael J. , Muldoon Joseph , Cherkezyan Lusik , Zhu Yuanjia , Bianchi Laura K. , Shah Dhiren , Pradhan Prabhakar , Borkar Monica , Lynch Henry , Backman Vadim
Published: April 2023

PDF file - 171K
Supplementary Figure 4 from Radiotherapy Increases the Permissiveness of Established Mammary Tumors to Rejection by Immunomodulatory Antibodies
Authors: Verbrugge Inge , Hagekyriakou Jim , Sharp Leslie L. , Galli Mara , West Alison , McLaughlin Nicole M. , Duret Hélène , Yagita Hideo , Johnstone Ricky W. , Smyth Mark J. , Haynes Nicole M.
Published: April 2023

PDF file - 55K, Side-by-side immunohistochemical analysis of the 4T1.2 (A) and AT-3 (B) tumor microenviroment
Supplementary Figure 3 from Radiotherapy Increases the Permissiveness of Established Mammary Tumors to Rejection by Immunomodulatory Antibodies
Authors: Verbrugge Inge , Hagekyriakou Jim , Sharp Leslie L. , Galli Mara , West Alison , McLaughlin Nicole M. , Duret Hélène , Yagita Hideo , Johnstone Ricky W. , Smyth Mark J. , Haynes Nicole M.
Published: April 2023

PDF file - 319K, Examination of the cellular mechanisms that contribute to the combined therapeutic efficacy of radiotherapy and alpha-CD137/alpha-CD40 therapy in established 4T1.2 tumors
Supplementary Table 1 from Targeting Protein Synthesis in a Myc/mTOR-Driven Model of Anorexia-Cachexia Syndrome Delays Its Onset and Prolongs Survival
Authors: Robert Francis , Mills John R. , Agenor Aouod , Wang Dantong , DiMarco Sergio , Cencic Regina , Tremblay Michel L. , Gallouzi Imed Eddine , Hekimi Siegfried , Wing Simon S. , Pelletier Jerry
Published: April 2023

PDF file - 61K
Supplementary Figure 2 from Radiotherapy Increases the Permissiveness of Established Mammary Tumors to Rejection by Immunomodulatory Antibodies
Authors: Verbrugge Inge , Hagekyriakou Jim , Sharp Leslie L. , Galli Mara , West Alison , McLaughlin Nicole M. , Duret Hélène , Yagita Hideo , Johnstone Ricky W. , Smyth Mark J. , Haynes Nicole M.
Published: April 2023

PDF file - 233K, Analysis of the combined therapeutic effects of radiotherapy and alpha-CD137/alpha-CD40 therapy in established 4T1.2 tumors
Supplementary Figure 9 from Targeting Protein Synthesis in a Myc/mTOR-Driven Model of Anorexia-Cachexia Syndrome Delays Its Onset and Prolongs Survival
Authors: Robert Francis , Mills John R. , Agenor Aouod , Wang Dantong , DiMarco Sergio , Cencic Regina , Tremblay Michel L. , Gallouzi Imed Eddine , Hekimi Siegfried , Wing Simon S. , Pelletier Jerry
Published: April 2023

PDF file - 247K
Supplementary Figure 8 from Targeting Protein Synthesis in a Myc/mTOR-Driven Model of Anorexia-Cachexia Syndrome Delays Its Onset and Prolongs Survival
Authors: Robert Francis , Mills John R. , Agenor Aouod , Wang Dantong , DiMarco Sergio , Cencic Regina , Tremblay Michel L. , Gallouzi Imed Eddine , Hekimi Siegfried , Wing Simon S. , Pelletier Jerry
Published: April 2023

PDF file - 453K
Supplementary Table 2 from Concordant Release of Glycolysis Proteins into the Plasma Preceding a Diagnosis of ER+ Breast Cancer
Authors: Amon Lynn M. , Pitteri Sharon J. , Li Christopher I. , McIntosh Martin , Ladd Jon J. , Disis Mary , Porter Peggy , Wong Chee Hong , Zhang Qing , Lampe Paul , Prentice Ross L. , Hanash Samir M.
Published: April 2023

PDF file - 52K
Supplementary Figure 6 from Targeting Protein Synthesis in a Myc/mTOR-Driven Model of Anorexia-Cachexia Syndrome Delays Its Onset and Prolongs Survival
Authors: Robert Francis , Mills John R. , Agenor Aouod , Wang Dantong , DiMarco Sergio , Cencic Regina , Tremblay Michel L. , Gallouzi Imed Eddine , Hekimi Siegfried , Wing Simon S. , Pelletier Jerry
Published: April 2023

PDF file - 328K
Supplementary Table 1 from Concordant Release of Glycolysis Proteins into the Plasma Preceding a Diagnosis of ER+ Breast Cancer
Authors: Amon Lynn M. , Pitteri Sharon J. , Li Christopher I. , McIntosh Martin , Ladd Jon J. , Disis Mary , Porter Peggy , Wong Chee Hong , Zhang Qing , Lampe Paul , Prentice Ross L. , Hanash Samir M.
Published: April 2023

PDF file - 81K
Supplementary Figure 5 from Targeting Protein Synthesis in a Myc/mTOR-Driven Model of Anorexia-Cachexia Syndrome Delays Its Onset and Prolongs Survival
Authors: Robert Francis , Mills John R. , Agenor Aouod , Wang Dantong , DiMarco Sergio , Cencic Regina , Tremblay Michel L. , Gallouzi Imed Eddine , Hekimi Siegfried , Wing Simon S. , Pelletier Jerry
Published: April 2023

PDF file - 775K
Supplementary Methods and Figure Legend from Systemic Combination Virotherapy for Melanoma with Tumor Antigen-Expressing Vesicular Stomatitis Virus and Adoptive T-cell Transfer
Authors: Rommelfanger Diana M. , Wongthida Phonphimon , Diaz Rosa M. , Kaluza Karen M. , Thompson Jill M. , Kottke Timothy J. , Vile Richard G.
Published: April 2023

PDF file, 96K.
Supplementary Figure 4 from Targeting Protein Synthesis in a Myc/mTOR-Driven Model of Anorexia-Cachexia Syndrome Delays Its Onset and Prolongs Survival
Authors: Robert Francis , Mills John R. , Agenor Aouod , Wang Dantong , DiMarco Sergio , Cencic Regina , Tremblay Michel L. , Gallouzi Imed Eddine , Hekimi Siegfried , Wing Simon S. , Pelletier Jerry
Published: April 2023

PDF file - 476K
Supplementary Figure 3 from Targeting Protein Synthesis in a Myc/mTOR-Driven Model of Anorexia-Cachexia Syndrome Delays Its Onset and Prolongs Survival
Authors: Robert Francis , Mills John R. , Agenor Aouod , Wang Dantong , DiMarco Sergio , Cencic Regina , Tremblay Michel L. , Gallouzi Imed Eddine , Hekimi Siegfried , Wing Simon S. , Pelletier Jerry
Published: April 2023

PDF file - 280K
Supplementary Figure 1 from Systemic Combination Virotherapy for Melanoma with Tumor Antigen-Expressing Vesicular Stomatitis Virus and Adoptive T-cell Transfer
Authors: Rommelfanger Diana M. , Wongthida Phonphimon , Diaz Rosa M. , Kaluza Karen M. , Thompson Jill M. , Kottke Timothy J. , Vile Richard G.
Published: April 2023

PDF file, 44K, Gr1 expression.
Supplementary Figure 10 from Targeting Protein Synthesis in a Myc/mTOR-Driven Model of Anorexia-Cachexia Syndrome Delays Its Onset and Prolongs Survival
Authors: Robert Francis , Mills John R. , Agenor Aouod , Wang Dantong , DiMarco Sergio , Cencic Regina , Tremblay Michel L. , Gallouzi Imed Eddine , Hekimi Siegfried , Wing Simon S. , Pelletier Jerry
Published: April 2023

PDF file - 274K
Supplementary Tables 1-3, Figure Legends 1-2 from Embryonic Protein Nodal Promotes Breast Cancer Vascularization
Authors: Quail Daniela F. , Walsh Logan A. , Zhang Guihua , Findlay Scott D. , Moreno Juan , Fung Laura , Ablack Amber , Lewis John D. , Done Susan J. , Hess David A. , Postovit Lynne-Marie
Published: April 2023

PDF file - 120K
Supplementary Figure 2 from Embryonic Protein Nodal Promotes Breast Cancer Vascularization
Authors: Quail Daniela F. , Walsh Logan A. , Zhang Guihua , Findlay Scott D. , Moreno Juan , Fung Laura , Ablack Amber , Lewis John D. , Done Susan J. , Hess David A. , Postovit Lynne-Marie
Published: April 2023

PDF file - 1MB, Nodal co-localizes with CD31 in human breast cancer
Supplementary Table 1 from AZD4547: An Orally Bioavailable, Potent, and Selective Inhibitor of the Fibroblast Growth Factor Receptor Tyrosine Kinase Family
Authors: Gavine Paul R. , Mooney Lorraine , Kilgour Elaine , Thomas Andrew P. , Al-Kadhimi Katherine , Beck Sarah , Rooney Claire , Coleman Tanya , Baker Dawn , Mellor Martine J. , Brooks A. Nigel , Klinowska Teresa
Published: April 2023

PDF file - 52K
Supplementary Figure 1 from Embryonic Protein Nodal Promotes Breast Cancer Vascularization
Authors: Quail Daniela F. , Walsh Logan A. , Zhang Guihua , Findlay Scott D. , Moreno Juan , Fung Laura , Ablack Amber , Lewis John D. , Done Susan J. , Hess David A. , Postovit Lynne-Marie
Published: April 2023

PDF file - 1.2MB, Nodal antibody used for IHC labels same cells as R&D antibody used in previous studies, but with less non-specific background staining
Supplementary Figure 2 from AZD4547: An Orally Bioavailable, Potent, and Selective Inhibitor of the Fibroblast Growth Factor Receptor Tyrosine Kinase Family
Authors: Gavine Paul R. , Mooney Lorraine , Kilgour Elaine , Thomas Andrew P. , Al-Kadhimi Katherine , Beck Sarah , Rooney Claire , Coleman Tanya , Baker Dawn , Mellor Martine J. , Brooks A. Nigel , Klinowska Teresa
Published: April 2023

PDF file - 61K
Supplementary Methods from LRP1B Deletion in High-Grade Serous Ovarian Cancers Is Associated with Acquired Chemotherapy Resistance to Liposomal Doxorubicin
Authors: Cowin Prue A. , George Joshy , Fereday Sian , Loehrer Elizabeth , Van Loo Peter , Cullinane Carleen , Etemadmoghadam Dariush , Ftouni Sarah , Galletta Laura , Anglesio Michael S. , Hendley Joy , Bowes Leanne , Sheppard Karen E. , Christie Elizabeth L. , Pearson Richard B. , Harnett Paul R. , Heinzelmann-Schwarz Viola , Friedlander Michael , McNally Orla , Quinn Michael , Campbell Peter , deFazio Anna , Bowtell David D.L.
Published: April 2023

PDF file - 150K
Supplementary Table 4 from Functional Interaction between Responses to Lactic Acidosis and Hypoxia Regulates Genomic Transcriptional Outputs
Authors: Tang Xiaohu , Lucas Joseph E. , Chen Julia Ling-Yu , LaMonte Gregory , Wu Jianli , Wang Michael Changsheng , Koumenis Constantinos , Chi Jen-Tsan
Published: April 2023

PDF file - 12K
Supplementary Table 3 from Functional Interaction between Responses to Lactic Acidosis and Hypoxia Regulates Genomic Transcriptional Outputs
Authors: Tang Xiaohu , Lucas Joseph E. , Chen Julia Ling-Yu , LaMonte Gregory , Wu Jianli , Wang Michael Changsheng , Koumenis Constantinos , Chi Jen-Tsan
Published: April 2023

PDF file - 8K
Supplementary Figure 1 from TGF-β and αvβ6 Integrin Act in a Common Pathway to Suppress Pancreatic Cancer Progression
Authors: Hezel Aram F. , Deshpande Vikram , Zimmerman Stephanie M. , Contino Gianmarco , Alagesan Brinda , O'Dell Michael R. , Rivera Lee B. , Harper Jay , Lonning Scott , Brekken Rolf A. , Bardeesy Nabeel
Published: April 2023

PDF file - 1.7MB, No significant alteration were detected in tumor stroma between treatment cohorts
Supplementary Table 1 from Perturbation of Rb, p53, and Brca1 or Brca2 Cooperate in Inducing Metastatic Serous Epithelial Ovarian Cancer
Authors: Szabova Ludmila , Yin Chaoying , Bupp Sujata , Guerin Theresa M. , Schlomer Jerome J. , Householder Deborah B. , Baran Maureen L. , Yi Ming , Song Yurong , Sun Wenping , McDunn Jonathan E. , Martin Philip L. , Van Dyke Terry , Difilippantonio Simone
Published: April 2023

PDF file - 53K, Tumor spectrum in Adeno-Cre injected mice
Supplementary Table 1 from Mesenchymal Stromal Cell Mutations and Wound Healing Contribute to the Etiology of Desmoid Tumors
Authors: Carothers Adelaide M. , Rizvi Hira , Hasson Rian M. , Heit Yvonne I. , Davids Jennifer S. , Bertagnolli Monica M. , Cho Nancy L.
Published: April 2023

PDf file - 56K
Supplementary Figure 5 from Perturbation of Rb, p53, and Brca1 or Brca2 Cooperate in Inducing Metastatic Serous Epithelial Ovarian Cancer
Authors: Szabova Ludmila , Yin Chaoying , Bupp Sujata , Guerin Theresa M. , Schlomer Jerome J. , Householder Deborah B. , Baran Maureen L. , Yi Ming , Song Yurong , Sun Wenping , McDunn Jonathan E. , Martin Philip L. , Van Dyke Terry , Difilippantonio Simone
Published: April 2023

PDF file - 253K, Gene expression analysis
Supplementary Figure 3 from Mesenchymal Stromal Cell Mutations and Wound Healing Contribute to the Etiology of Desmoid Tumors
Authors: Carothers Adelaide M. , Rizvi Hira , Hasson Rian M. , Heit Yvonne I. , Davids Jennifer S. , Bertagnolli Monica M. , Cho Nancy L.
Published: April 2023

PDF file - 4.1MB, Cell morphology of desmoid-derived MSC line was polyploid. Morphological features of first passage cells cultured from a DT are shown at low (A), intermediate (B), and high (C) densities. Cells aligned at high density (white arrow) to form sites of extensive cell-cell contact denoting polarity. Clusters of cells at high density spontaneously differentiated into neuronal-like cells (D). Original magnification was 10X.
Supplementary Figure 5 from NAC1 Is an Actin-Binding Protein That Is Essential for Effective Cytokinesis in Cancer Cells
Authors: Yap Kai Lee , Fraley Stephanie I. , Thiaville Michelle M. , Jinawath Natini , Nakayama Kentaro , Wang Jianlong , Wang Tian-Li , Wirtz Denis , Shih Ie-Ming
Published: April 2023

PDF file - 63K, mOSE cells of NAC1 knockout mouse
Supplementary Figure 3 from NAC1 Is an Actin-Binding Protein That Is Essential for Effective Cytokinesis in Cancer Cells
Authors: Yap Kai Lee , Fraley Stephanie I. , Thiaville Michelle M. , Jinawath Natini , Nakayama Kentaro , Wang Jianlong , Wang Tian-Li , Wirtz Denis , Shih Ie-Ming
Published: April 2023

PDF file - 100K, Time lapse frames of shRNA treated HeLa cells
Supplementary Video 2 from RALBP1/RLIP76 Depletion in Mice Suppresses Tumor Growth by Inhibiting Tumor Neovascularization
Authors: Lee Seunghyung , Wurtzel Jeremy G. T. , Singhal Sharad S. , Awasthi Sanjay , Goldfinger Lawrence E.
Published: April 2023

MOV file - 696K, 3D muCT reconstruction of the vasculature in a B16F10 tumor derived in a RLIP76-/- mouse
Supplementary Figure 1 from NAC1 Is an Actin-Binding Protein That Is Essential for Effective Cytokinesis in Cancer Cells
Authors: Yap Kai Lee , Fraley Stephanie I. , Thiaville Michelle M. , Jinawath Natini , Nakayama Kentaro , Wang Jianlong , Wang Tian-Li , Wirtz Denis , Shih Ie-Ming
Published: April 2023

PDF file - 147K, Effects of inactivating NAC1 in HeLa N130 tTA cell line
Supplementary Video 1 from RALBP1/RLIP76 Depletion in Mice Suppresses Tumor Growth by Inhibiting Tumor Neovascularization
Authors: Lee Seunghyung , Wurtzel Jeremy G. T. , Singhal Sharad S. , Awasthi Sanjay , Goldfinger Lawrence E.
Published: April 2023

MOV file - 983K, 3D muCT reconstruction of the vasculature in a B16F10 tumor derived in a wild type mouse
Supplementary Methods, Figure Legends 1-4, Table Legends 1-2 from Kidney Tumor Biomarkers Revealed by Simultaneous Multiple Matrix Metabolomics Analysis
Authors: Ganti Sheila , Taylor Sandra L. , Abu Aboud Omran , Yang Joy , Evans Christopher , Osier Michael V. , Alexander Danny C. , Kim Kyoungmi , Weiss Robert H.
Published: April 2023

PDF file - 74K, Summary of all Supplemental data and Detailed methods: Non-targeted metabolomic analysis part of Supplemental Data
Supplementary Figure 3 from Primary Tumor Hypoxia Recruits CD11b+/Ly6Cmed/Ly6G+ Immune Suppressor Cells and Compromises NK Cell Cytotoxicity in the Premetastatic Niche
Authors: Sceneay Jaclyn , Chow Melvyn T. , Chen Anna , Halse Heloise M. , Wong Christina S.F. , Andrews Daniel M. , Sloan Erica K. , Parker Belinda S. , Bowtell David D. , Smyth Mark J. , Möller Andreas
Published: April 2023

PDF file - 33K, A/B) Reduction of CD11b+/Ly6Cmed but not CD11b+/Ly6Chigh cells in pre-metastatic niche induced by HCM after MCP-1 neutralization
Supplementary Figure 1 from Suppression of Tak1 Promotes Prostate Tumorigenesis
Authors: Wu Min , Shi Lihong , Cimic Adela , Romero Lina , Sui Guangchao , Lees Cynthia J. , Cline J. Mark , Seals Darren F. , Sirintrapun Joseph S. , McCoy Thomas P. , Liu Wennuan , Kim Jin Woo , Hawkins Gregory A. , Peehl Donna M. , Xu Jianfeng , Cramer Scott D.
Published: April 2023

PDF file - 949K, Expression of Tak1 Is Correlated with High Grade of Tumor in Human Prostate.
Supplementary Figure 1 from Antigen Shedding May Improve Efficiencies for Delivery of Antibody-Based Anticancer Agents in Solid Tumors
Authors: Pak Youngshang , Zhang Yujian , Pastan Ira , Lee Byungkook
Published: April 2023

PDF file - 343K, A schematic of RIT intracellular trafficking pathways
Supplementary Figure 3 from AMPK Promotes p53 Acetylation via Phosphorylation and Inactivation of SIRT1 in Liver Cancer Cells
Authors: Lee Chi-Wai , Wong Leo Lap-Yan , Tse Edith Yuk-Ting , Liu Heong-Fai , Leong Veronica Yee-Law , Lee Joyce Man-Fong , Hardie D. Grahame , Ng Irene Oi-Lin , Ching Yick-Pang
Published: April 2023

PDF file - 721K, Mutation of T344 did not alter SIRT1 sub-cellular localization
Supplementary Figure 4 from ATR–ATRIP Kinase Complex Triggers Activation of the Fanconi Anemia DNA Repair Pathway
Authors: Shigechi Tomoko , Tomida Junya , Sato Koichi , Kobayashi Masahiko , Eykelenboom John K. , Pessina Fabio , Zhang Yanbin , Uchida Emi , Ishiai Masamichi , Lowndes Noel F. , Yamamoto Kenichi , Kurumizaka Hitoshi , Maehara Yoshihiko , Takata Minoru
Published: April 2023

PDF file - 1MB
Supplementary Figures 1-2, Gene Data from Hedgehog and Notch Signaling Regulate Self-Renewal of Undifferentiated Pleomorphic Sarcomas
Authors: Wang Chang Ye Yale , Wei Qingxia , Han Ilkyu , Sato Shingo , Azarnier Ronak Ghanbari- , Whetstone Heather , Poon Raymond , Hu Jiayi , Zheng Feifei , Zhang Phil , Wang Weishi , Wunder Jay S. , Alman Benjamin A.
Published: April 2023

PDF file - 3.4MB
Supplementary Methods from Fibroblast-Derived Dermal Matrix Drives Development of Aggressive Cutaneous Squamous Cell Carcinoma in Patients with Recessive Dystrophic Epidermolysis Bullosa
Authors: Ng Yi-Zhen , Pourreyron Celine , Salas-Alanis Julio C. , Dayal Jasbani H.S. , Cepeda-Valdes Rodrigo , Yan Wenfei , Wright Sheila , Chen Mei , Fine Jo-David , Hogg Fiona J. , McGrath John A. , Murrell Dedee F. , Leigh Irene M. , Lane E. Birgit , South Andrew P.
Published: April 2023

PDF file - 382K, Includes Microarray and Expression Analysis, BRB Array Clustering Analysis, and Tumorigenicity assays
Supplementary Figure Legends 1-3 from FLT-PET Is Superior to FDG-PET for Very Early Response Prediction in NPM-ALK-Positive Lymphoma Treated with Targeted Therapy
Authors: Li Zhoulei , Graf Nicolas , Herrmann Ken , Jünger Alexandra , Aichler Michaela , Feuchtinger Annette , Baumgart Anja , Walch Axel , Peschel Christian , Schwaiger Markus , Buck Andreas , Keller Ulrich , Dechow Tobias
Published: April 2023

PDF file - 101K
Supplementary Figure 2 from FLT-PET Is Superior to FDG-PET for Very Early Response Prediction in NPM-ALK-Positive Lymphoma Treated with Targeted Therapy
Authors: Li Zhoulei , Graf Nicolas , Herrmann Ken , Jünger Alexandra , Aichler Michaela , Feuchtinger Annette , Baumgart Anja , Walch Axel , Peschel Christian , Schwaiger Markus , Buck Andreas , Keller Ulrich , Dechow Tobias
Published: April 2023

PDF file - 51K, Effect of everolimus on SUDHL-1 cells in vitro
Supplementary Table 2 from Resistance to Selective BRAF Inhibition Can Be Mediated by Modest Upstream Pathway Activation
Authors: Su Fei , Bradley William D. , Wang Qiongqing , Yang Hong , Xu Lizhong , Higgins Brian , Kolinsky Kenneth , Packman Kathryn , Kim Min Jung , Trunzer Kerstin , Lee Richard J. , Schostack Kathleen , Carter Jade , Albert Thomas , Germer Soren , Rosinski Jim , Martin Mitchell , Simcox Mary Ellen , Lestini Brian , Heimbrook David , Bollag Gideon
Published: April 2023

PDF file - 50K
Supplementary Figure 1 from Resistance to Selective BRAF Inhibition Can Be Mediated by Modest Upstream Pathway Activation
Authors: Su Fei , Bradley William D. , Wang Qiongqing , Yang Hong , Xu Lizhong , Higgins Brian , Kolinsky Kenneth , Packman Kathryn , Kim Min Jung , Trunzer Kerstin , Lee Richard J. , Schostack Kathleen , Carter Jade , Albert Thomas , Germer Soren , Rosinski Jim , Martin Mitchell , Simcox Mary Ellen , Lestini Brian , Heimbrook David , Bollag Gideon
Published: April 2023

PDF file - 28K
Supplementary Table 6 from ESE3/EHF Controls Epithelial Cell Differentiation and Its Loss Leads to Prostate Tumors with Mesenchymal and Stem-like Features
Authors: Albino Domenico , Longoni Nicole , Curti Laura , Mello-Grand Maurizia , Pinton Sandra , Civenni Gianluca , Thalmann George , D'Ambrosio Gioacchino , Sarti Manuela , Sessa Fausto , Chiorino Giovanna , Catapano Carlo V. , Carbone Giuseppina M.
Published: April 2023

XLS file - 168K, Genes up- and down- regulated in ESE3low tumors compared to all tumors (Q<0.05)
Supplementary Table 3 from ESE3/EHF Controls Epithelial Cell Differentiation and Its Loss Leads to Prostate Tumors with Mesenchymal and Stem-like Features
Authors: Albino Domenico , Longoni Nicole , Curti Laura , Mello-Grand Maurizia , Pinton Sandra , Civenni Gianluca , Thalmann George , D'Ambrosio Gioacchino , Sarti Manuela , Sessa Fausto , Chiorino Giovanna , Catapano Carlo V. , Carbone Giuseppina M.
Published: April 2023

PDF file - 7K, Identification of ETS binding site on the promoter of putative ESE3 target genes
Supplementary Figure 4 from CCN6 Modulates BMP Signaling via the Smad-Independent TAK1/p38 Pathway, Acting to Suppress Metastasis of Breast Cancer
Authors: Pal Anupama , Huang Wei , Li Xin , Toy Kathy A. , Nikolovska-Coleska Zaneta , Kleer Celina G.
Published: April 2023

PDF file, 90K, Co-localization of CCN6 and BMP4 in clinical samples of breast cancer.
Supplementary Figure 1 from CCN6 Modulates BMP Signaling via the Smad-Independent TAK1/p38 Pathway, Acting to Suppress Metastasis of Breast Cancer
Authors: Pal Anupama , Huang Wei , Li Xin , Toy Kathy A. , Nikolovska-Coleska Zaneta , Kleer Celina G.
Published: April 2023

PDF file, 121K, Confocal images and immunoblot analysis of HME CCN6 KD and control cells grown in 3D for 15 days. CCN6 KD led to disruption of acinar organization and decreased expression of E-cadherin protein. β-Actin was used as loading control.
Supplementary Methods from The T-cell Receptor Repertoire of Tumor-Infiltrating Regulatory T Lymphocytes Is Skewed Toward Public Sequences
Authors: Sainz-Perez Alexander , Lim Annick , Lemercier Brigitte , Leclerc Claude
Published: April 2023

PDF file - 59K, Supplementary Methods include quantitative analysis, as well as cloning and sequencing data.
Supplementary Figure 4 from Augmentation of Therapeutic Responses in Melanoma by Inhibition of IRAK-1,-4
Authors: Srivastava Ratika , Geng Degui , Liu Yingjia , Zheng Liqin , Li Zhaoyang , Joseph Mary Ann , McKenna Colleen , Bansal Navneeta , Ochoa Augusto , Davila Eduardo
Published: April 2023

PDF file - 66K, Apoptosis-related gene transcription array of A375 melanoma cells following IRAK inhibition with or without vinblastine
Supplementary Figure 2 from Augmentation of Therapeutic Responses in Melanoma by Inhibition of IRAK-1,-4
Authors: Srivastava Ratika , Geng Degui , Liu Yingjia , Zheng Liqin , Li Zhaoyang , Joseph Mary Ann , McKenna Colleen , Bansal Navneeta , Ochoa Augusto , Davila Eduardo
Published: April 2023

PDF file - 48K, Inhibiting IRAK-1/-4 abrogates the effects of TLR1-TLR2 agonist in melanoma cells
Supplementary Figure 1 from Augmentation of Therapeutic Responses in Melanoma by Inhibition of IRAK-1,-4
Authors: Srivastava Ratika , Geng Degui , Liu Yingjia , Zheng Liqin , Li Zhaoyang , Joseph Mary Ann , McKenna Colleen , Bansal Navneeta , Ochoa Augusto , Davila Eduardo
Published: April 2023

PDF file - 77K, Overexpressing IRAK-1 in melanoma cells augments the expression of various cytokines and chemokines
Supplementary Data 4 from An NMR Metabolomics Approach for the Diagnosis of Leptomeningeal Carcinomatosis
Authors: Cho Hye Rim , Wen He , Ryu Young Jin , An Yong Jin , Kim Hyo Cheol , Moon Woo Kyung , Han Moon Hee , Park Sunghyouk , Choi Seung Hong
Published: April 2023

PDF file - 66K, The absolute concentration of the marker metabolites at each experimental time points
Supplementary Tables 2-4 from Distinct microRNA Expression Profiles in Prostate Cancer Stem/Progenitor Cells and Tumor-Suppressive Functions of let-7
Authors: Liu Can , Kelnar Kevin , Vlassov Alexander V. , Brown David , Wang Junchen , Tang Dean G.
Published: April 2023

PDF file - 190K
Supplementary Figure 2 from Smac Mimetic LBW242 Sensitizes XIAP-Overexpressing Neuroblastoma Cells for TNF-α–Independent Apoptosis
Authors: Eschenburg Georg , Eggert Angelika , Schramm Alexander , Lode Holger N. , Hundsdoerfer Patrick
Published: April 2023

PDF file - 1.7MB, Effect of XIAP silencing by specific antisense oligonucleotide on apoptosis induction in neuroblastoma cells.
Supplementary Tables 1-7 from ARN-509: A Novel Antiandrogen for Prostate Cancer Treatment
Authors: Clegg Nicola J. , Wongvipat John , Joseph James D. , Tran Chris , Ouk Samedy , Dilhas Anna , Chen Yu , Grillot Kate , Bischoff Eric D. , Cai Ling , Aparicio Anna , Dorow Steven , Arora Vivek , Shao Gang , Qian Jing , Zhao Hong , Yang Guangbin , Cao Chunyan , Sensintaffar John , Wasielewska Teresa , Herbert Mark R. , Bonnefous Celine , Darimont Beatrice , Scher Howard I. , Smith-Jones Peter , Klang Mark , Smith Nicholas D. , De Stanchina Elisa , Wu Nian , Ouerfelli Ouathek , Rix Peter J. , Heyman Richard A. , Jung Michael E. , Sawyers Charles L. , Hager Jeffrey H.
Published: April 2023

PDF file - 151K
Supplementary Figure 5 from ARN-509: A Novel Antiandrogen for Prostate Cancer Treatment
Authors: Clegg Nicola J. , Wongvipat John , Joseph James D. , Tran Chris , Ouk Samedy , Dilhas Anna , Chen Yu , Grillot Kate , Bischoff Eric D. , Cai Ling , Aparicio Anna , Dorow Steven , Arora Vivek , Shao Gang , Qian Jing , Zhao Hong , Yang Guangbin , Cao Chunyan , Sensintaffar John , Wasielewska Teresa , Herbert Mark R. , Bonnefous Celine , Darimont Beatrice , Scher Howard I. , Smith-Jones Peter , Klang Mark , Smith Nicholas D. , De Stanchina Elisa , Wu Nian , Ouerfelli Ouathek , Rix Peter J. , Heyman Richard A. , Jung Michael E. , Sawyers Charles L. , Hager Jeffrey H.
Published: April 2023

PDF file - 483K
Supplementary Figure 3 from ARN-509: A Novel Antiandrogen for Prostate Cancer Treatment
Authors: Clegg Nicola J. , Wongvipat John , Joseph James D. , Tran Chris , Ouk Samedy , Dilhas Anna , Chen Yu , Grillot Kate , Bischoff Eric D. , Cai Ling , Aparicio Anna , Dorow Steven , Arora Vivek , Shao Gang , Qian Jing , Zhao Hong , Yang Guangbin , Cao Chunyan , Sensintaffar John , Wasielewska Teresa , Herbert Mark R. , Bonnefous Celine , Darimont Beatrice , Scher Howard I. , Smith-Jones Peter , Klang Mark , Smith Nicholas D. , De Stanchina Elisa , Wu Nian , Ouerfelli Ouathek , Rix Peter J. , Heyman Richard A. , Jung Michael E. , Sawyers Charles L. , Hager Jeffrey H.
Published: April 2023

PDF file- 366K
Supplementary Figure 2 from ARN-509: A Novel Antiandrogen for Prostate Cancer Treatment
Authors: Clegg Nicola J. , Wongvipat John , Joseph James D. , Tran Chris , Ouk Samedy , Dilhas Anna , Chen Yu , Grillot Kate , Bischoff Eric D. , Cai Ling , Aparicio Anna , Dorow Steven , Arora Vivek , Shao Gang , Qian Jing , Zhao Hong , Yang Guangbin , Cao Chunyan , Sensintaffar John , Wasielewska Teresa , Herbert Mark R. , Bonnefous Celine , Darimont Beatrice , Scher Howard I. , Smith-Jones Peter , Klang Mark , Smith Nicholas D. , De Stanchina Elisa , Wu Nian , Ouerfelli Ouathek , Rix Peter J. , Heyman Richard A. , Jung Michael E. , Sawyers Charles L. , Hager Jeffrey H.
Published: April 2023

PDF file - 241K
Supplementary Figures 1-6, Methods from Defective NF-κB Signaling in Metastatic Head and Neck Cancer Cells Leads to Enhanced Apoptosis by Double-Stranded RNA
Authors: Umemura Naoki , Zhu Jianzhong , Mburu Yvonne K. , Forero Adriana , Hsieh Paishiun N. , Muthuswamy Ravikumar , Kalinski Pawel , Ferris Robert L. , Sarkar Saumendra N.
Published: April 2023

PDF file - 520K
Supplementary Table 3 from Leptin and Soluble Leptin Receptor in Risk of Colorectal Cancer in the European Prospective Investigation into Cancer and Nutrition Cohort
Authors: Aleksandrova Krasimira , Boeing Heiner , Jenab Mazda , Bueno-de-Mesquita H. Bas , Jansen Eugene , van Duijnhoven Fränzel J. B. , Rinaldi Sabina , Fedirko Veronika , Romieu Isabelle , Riboli Elio , Gunter Marc J. , Westphal Sabine , Overvad Kim , Tjønneland Anne , Halkjær Jytte , Racine Antoine , Boutron-Ruault Marie-Christine , Clavel-Chapelon Françoise , Kaaks Rudolf , Lukanova Annekatrin , Trichopoulou Antonia , Lagiou Pagona , Trichopoulos Dimitrios , Mattiello Amalia , Pala Valeria , Palli Domenico , Tumino Rosario , Vineis Paolo , Buckland Genevieve , Sánchez María-José , Amiano Pilar , Huerta José María , Barricarte Aurelio , Menéndez Virginia , Peeters Petra H. , Söderberg Stefan , Palmqvist Richard , Allen Naomi E. , Crowe Francesca L. , Khaw Kay-Tee , Wareham Nickolas , Pischon Tobias
Published: April 2023

PDF file - 127K, Relative risks (RR-s)* and 95% confidence intervals (CI-s) of colorectal cancer associated with a doubling in leptin and sOB-R concentrations, by subgroups, the European Prospective Investigation into Cancer and Nutrition (EPIC), 1992-2003
Supplementary Materials and Methods from The MET Oncogene Is a Functional Marker of a Glioblastoma Stem Cell Subtype
Authors: De Bacco Francesca , Casanova Elena , Medico Enzo , Pellegatta Serena , Orzan Francesca , Albano Raffaella , Luraghi Paolo , Reato Gigliola , D'Ambrosio Antonio , Porrati Paola , Patanè Monica , Maderna Emanuela , Pollo Bianca , Comoglio Paolo M. , Finocchiaro Gaetano , Boccaccio Carla
Published: April 2023

PDF file - 125K
Supplementary Table 2 from Leptin and Soluble Leptin Receptor in Risk of Colorectal Cancer in the European Prospective Investigation into Cancer and Nutrition Cohort
Authors: Aleksandrova Krasimira , Boeing Heiner , Jenab Mazda , Bueno-de-Mesquita H. Bas , Jansen Eugene , van Duijnhoven Fränzel J. B. , Rinaldi Sabina , Fedirko Veronika , Romieu Isabelle , Riboli Elio , Gunter Marc J. , Westphal Sabine , Overvad Kim , Tjønneland Anne , Halkjær Jytte , Racine Antoine , Boutron-Ruault Marie-Christine , Clavel-Chapelon Françoise , Kaaks Rudolf , Lukanova Annekatrin , Trichopoulou Antonia , Lagiou Pagona , Trichopoulos Dimitrios , Mattiello Amalia , Pala Valeria , Palli Domenico , Tumino Rosario , Vineis Paolo , Buckland Genevieve , Sánchez María-José , Amiano Pilar , Huerta José María , Barricarte Aurelio , Menéndez Virginia , Peeters Petra H. , Söderberg Stefan , Palmqvist Richard , Allen Naomi E. , Crowe Francesca L. , Khaw Kay-Tee , Wareham Nickolas , Pischon Tobias
Published: April 2023

PDF file - 80K, Relative risks (RR-s) and 95% confidence intervals (CI-s) of colon, rectal and colorectal cancer according to quintiles of free leptin index (FLI), the European Prospective Investigation into Cancer and Nutrition (EPIC), 1992-2003
Supplementary Figures 1-9 from The MET Oncogene Is a Functional Marker of a Glioblastoma Stem Cell Subtype
Authors: De Bacco Francesca , Casanova Elena , Medico Enzo , Pellegatta Serena , Orzan Francesca , Albano Raffaella , Luraghi Paolo , Reato Gigliola , D'Ambrosio Antonio , Porrati Paola , Patanè Monica , Maderna Emanuela , Pollo Bianca , Comoglio Paolo M. , Finocchiaro Gaetano , Boccaccio Carla
Published: April 2023

PDF file - 2.3MB, Figure S1: Histopathology of primary glioblastomas and genetic lesions of neurospheres. Figure S2: Genome-wide expression profiling and unsupervised hierarchical clustering of neurospheres (classical, mesenchymal and proneural centroids). Figure S3: Expression of MET, EGFR, and a panel of self-renewal markers in neurospheres. Figure S4: Genome-wide expression profiling and unsupervised hierarchical clustering of neurospheres (multiple signatures). Figure S5: Proliferative response, activation of tyrosine kinase receptors, and differentiation pattern in Met-neg-NS and Met-pos-NS. Figure S6: Methigh and Metneg sorting parameters. Figure S7: The Methigh subpopulation of Met-pos-NS retains clonogenic and tumorigenic cells. Figure S8: H&E and Met immunohistochemical staining of histological sections from tumors formed by BT302 neurosphere and its sorted subpopulations. Figure S9: HGF sustains the stem-like and invasive phenotype of Met-pos-NS.
Supplementary Table 2 from BCL2 Suppresses PARP1 Function and Nonapoptotic Cell Death
Authors: Dutta Chaitali , Day Tovah , Kopp Nadja , van Bodegom Diederik , Davids Matthew S. , Ryan Jeremy , Bird Liat , Kommajosyula Naveen , Weigert Oliver , Yoda Akinori , Fung Hua , Brown Jennifer R. , Shapiro Geoffrey I. , Letai Anthony , Weinstock David M.
Published: April 2023

PDF file - 18K, Clinical characteristics for the 14 patients outlined in Figure 6A. The majority of cases were previously untreated and harbored 13q deletion, the most common cytogenetic abnormality in CLL. Several higher risk patients with unmutated IGHV, positive ZAP-70, or adverse cytogenetics were also assessed