bluuebunny/crossref_metadata_2025 huggingface dataset:
ASSISTÊNCIA INTEGRADA A IDOSOS EM SITUAÇÃO DE POBREZA NO CONTEXTO DOS CUIDADOS PALIATIVOS
Authors: ARRUDA FERNANDA RODRIGUES , SOUZA BÁRBARA PRISCILA ALVES DE , MAGNAGO LARISSA TRINDADE , PRISTILO CAROLINE BIGATON , VIEIRA VITHÓRIA EMANUELLE SOUTO , STEINER TÚLIO DOERNER , CAVALCANTE RAFAEL LEITUGA DE CARVALHO , LÓPEZ ANDRES SANTIAGO QUIZHPI , JESUS DAYARA CARVALHO DE , DUARTE ALINE GRAZIELE GODOY
Published: September 2024

O envelhecimento populacional e a pobreza apresentam desafios significativos para a provisão de cuidados
paliativos integrados a idosos em condições de vulnerabilidade. Este estudo teve como objetivo revisar a
literatura sobre a assistência integrada a idosos em situação de pobreza no contexto dos cuidados paliativos,
identificando estratégias, barreiras e oportunidades para melhorar a qualidade de vida dessa população. Foi
realizada uma revisão narrativa de literatura utilizando bases de dados como PubMed, Scopus, Web of Science,
SciELO e Lilacs, com artigos publicados nos últimos 10 anos. Os critérios de inclusão consideraram estudos
quantitativos, qualitativos e revisões sistemáticas pertinentes ao tema. Os resultados mostraram que a assistência
integrada pode enfrentar desafios relacionados à falta de recursos, políticas públicas insuficientes e treinamentos
inadequados, embora evidências apontem para modelos de cuidado bem-sucedidos em alguns contextos. A
discussão enfatizou a necessidade de políticas públicas mais robustas e de uma maior colaboração intersetorial
para promover práticas efetivas. Concluiu-se que, para superar as barreiras identificadas, é essencial desenvolver
intervenções adaptadas aos contextos locais e ampliar as evidências que fundamentem políticas e práticas de
cuidados paliativos equitativos e integrados. Recomenda-se a realização de estudos futuros que avaliem o
impacto de intervenções integradas a longo prazo e explorem novas formas de colaboração entre setores de saúde
e assistência social.
EDUCAÇÃO SEXUAL NAS ESCOLAS: UM AGENTE DE MUDANÇA SOCIAL
Authors: MENDONÇA MATHEUS MENDES , NASCIMENTO ANY GABRIELY GONÇALVES , GUIMARÃES BRUNA MACÊDO , CASTRO JORDANA MAGDA DA SILVA E , ABDALA LAURA MARIA SANTOS , RIBEIRO LEONARDO BERNARDES , NASCIMENTO LOUISE DE CARVALHO , ANANIAS MARIANA MILLENA PEREIRA , PEREIRA MILENY SANTOS , FERNANDES LUCIANA CAETANO
Published: September 2024

Introdução: A educação sexual é um dos pontos chaves para fortalecimento de uma saúde pública segura,
principalmente entre adolescentes, sua apresentação desde o inicio da puberdade pode gerar diversos
mecanismos de combate à gravidez precoce e doenças sexualmente transmissíveis. Objetivo: Este capítulo
delineia a experiência de discentes do curso de Medicina, sob a orientação da coordenadora da Secretaria de
Extensão, da Universidade Evangélica de Goiás, durante uma ação extensionista realizada em uma instituição
de ensino pública situada em Anápolis, Goiás. Metodologia: Foi realizado um relato de experiência acerca de
uma ação realizada em uma escola pública na periferia da cidade de Anápolis, o relato utilizou construção teórica

com base em artigos e outros relatos sobre a mesma temática. Resultados e Discussão: A ação em foco centrou-
se na temática da educação sexual na adolescência, sendo o alvo adolescentes de 14 à 16 anos, abordando os

diversos riscos associados à gravidez precoce e às infecções sexualmente transmissíveis através de palestras,
demonstrações em modelos anatômicos e participação ativa dos estudantes. Considerações finais: A partir da
interação dos estudantes universitários com os adolescentes, tornou-se evidente a relevância da educação sexual
durante o período da puberdade, assim como seu impacto na orientação dos jovens para uma vida sexual saudável
e consciente dos riscos envolvidos.
FORTALECENDO A SAÚDE DA FAMÍLIA ATRAVÉS DA ATENÇÃO PRIMÁRIA
Authors: TONELLO NEILA DUTRA , PINTO TOM MOREIRA , ANJOS JOSÉ DE ALENCAR LIMA DOS , AMARAL PRÍSCILA GAVILANES , NOGUEIRA VICTÓRIA RIBEIRO , CAVALCANTE IARA NEVES VIEIRA , SILVA NIKOLLE BARBOSA DA , GILBERTONI JOÃO PEDRO , GILBERTONI GUILHERME , NUNES ROSELI BARBOSA
Published: September 2024

Introdução: A Atenção Primária à Saúde (APS) é considerada a base dos sistemas de saúde globalmente,
especialmente em países que buscam garantir acesso universal e equitativo aos cuidados de saúde. No Brasil, a
Estratégia de Saúde da Família (ESF) foi implementada como modelo prioritário de APS, desempenhando um
papel essencial na promoção da saúde, prevenção de doenças e organização do cuidado integral. Objetivo: Este
estudo teve por objetivo revisar a importância da ESF. Metodologia: A pesquisa utilizou uma revisão narrativa
da literatura, envolvendo a consulta a bases de dados como PubMed, SciELO e LILACS, e aplicando descritores
específicos para identificar estudos relevantes entre 2002 e 2023. Dos 645 estudos inicialmente identificados, 13
foram selecionados como base teórica. Resultados e Discussões: Indicam que a ESF, com sua abordagem
centrada na comunidade e em equipes multiprofissionais, é fundamental para melhorar a acessibilidade,
coordenação, integralidade e longitudinalidade do cuidado. No entanto, a ESF ainda enfrenta desafios, como a
necessidade de maior financiamento, melhor gestão, capacitação contínua de profissionais e integração eficiente
dos níveis de atenção. Conclusão: Conclui-se que o fortalecimento da APS e da ESF no Brasil requer estratégias
integradas que considerem as especificidades locais, enfrentem desigualdades regionais e promovam a equidade
em saúde. A adoção de tecnologias inovadoras, a valorização dos profissionais de saúde e o reforço da
participação social são essenciais para garantir que a APS continue cumprindo seu papel estratégico no Sistema
Único de Saúde (SUS), promovendo um sistema de saúde mais justo, equitativo e eficiente.
Desafios e soluções
Authors: Souza Ana Cristina França , Castor Katia Gonçalves
Published: September 2024

A publicação é o resultado de um estudo conduzido no âmbito de uma Dissertação de Mestrado Profissional apresentada ao Programa de Pós-Graduação em Ciências, Tecnologia e Educação do Centro Universitário Vale do Cricaré, como tema COLABORAÇÃO INTERPROFISSIONAL NA EDUCAÇÃO ESPECIAL EM UMA ESCOLA MUNICIPAL DE SÃO MATEUS/ES: PERCEPÇÕES E DESAFIOS. A pesquisa envolveu a colaboração de dez profissionais, sendo uma pedagoga, quatro professoras regente de sala, quatro professoras auxiliar e a professora de Atendimento Educacional Especializado (PAEE). Esses profissionais desempenham papéis cruciais no processo de ensino-aprendizagem de alunos com deficiência, na Rede Pública Municipal da Cidade de São Mateus - ES.
AVALIAÇÃO CARDIORESPIRATÓRIA
Authors: Barbisan Silmar Alexandre
Published: September 2024

Respostas fisiológicas variadas ao exercício são usadas para AVALIAR a APTIDÃO CARDIORRESPIRATÓRIA (CR), incluindo o consumo de oxigênio (VO²), a frequência cardíaca e a pressão arterial. A medida dessas variáveis durante o exercício físico, particularmente o EXERCÍCIOS MÁXIMO, faz aumentar a probabilidade de detectarmos qualquer doença arterial coronariana ou doença pulmonar.
Pengaruh Pemasaran Digital dan Customer Review terhadap Minat Beli Konsumen pada Pengguna Aplikasi Shopee di Kota Surabaya
Authors: Fadhilla Alfidha Nur , Iswati Iswati , Fitriyasari Anis
Published: September 2024

Penelitian ini bertujuan untuk menganalisis pengaruh pemasaran digital dan customer review terhadap minat beli konsumen pada pengguna aplikasi shopee di Kota Surabaya. Penelitian ini menggunakan metode kuantitatif dengan pendekatan survei, dimana data yang dikumpulkan melalui kuisioner secara online dengan jumlah responden sebanyak 140. Analisis data dilakukan dengan menggunakan regresi linear berganda untuk mengetahui pengaruh variabel independen (pemasaran digital dan customer review) terhadap variabel dependen (minat beli konsumen). Hasil penelitian menunjukkan bahwa pemasaran digital memiliki pengaruh positif dan signifikan terhadap minat beli konsumen. Strategi pemasaran digital yang efektif, seperti penggunaan media sosial, iklan online, dan promosi melalui influencer, terbukti mampu meningkatkan minat beli konsumen. Selain itu, customer review juga memiliki pengaruh positif dan signifikan terhadap minat beli konsumen. Ulasan yang positif dari pelanggan lain memberikan kepercayaan dan keyakinan kepada konsumen untuk melakukan pembelian. Secara keseluruhan, penelitian ini menegaskan pentingnya pemasaran digital dan customer review dalam meningkatkan minat beli konsumen. Temuan ini memberikan implikasi praktis bagi para pelaku bisnis e-commerce, khususnya shopee, untuk lebih fokus pada strategi pemasaran digital yang inovatif dan pengelolaan ulasan pelanggan yang baik guna meningkatkan minat beli konsumen di Surabaya.
Dampak Tingkat Pendidikan terhadap Kemiskinan di Sumatera Utara Tahun 2017-2021
Authors: Togatorop Rey Septanislaus , Sinaga Maysri Handayani Putri , Putri Nazwa Aulia , Hafifah Roihanah , Nuraina Azra Lena
Published: September 2024

Penelitian ini bertujuan untuk menyelidiki hubungan antara tingkat pendidikan dan tingkat kemiskinan di Sumatera Utara selama periode 2017-2021. Data yang digunakan bersumber dari Badan Pusat Statistik (BPS) dan dianalisis menggunakan metode regresi linier melalui perangkat lunak Statistical Package for the Social Sciences (SPSS). Sampel penelitian mencakup data sekunder yang mencatat tingkat pendidikan dan tingkat kemiskinan di Sumatera Utara. Hasil analisis menunjukkan adanya hubungan yang signifikan antara tingkat pendidikan dan tingkat kemiskinan di wilayah tersebut.
The Influence of Population and Government Expenditure on Surakarta City Original Revenue 2006-2023
Authors: Wijaya Fahnur Ari , Arisetyawan Kukuh , Fisabilillah Ladi Wajuba Perdini , Putri Risqi Noor Hidayati
Published: September 2024

One of the problems that still occurs in the region until now is the problem of regional finance. This study aims to determine whether population and government expenditure have an influence on local revenue in Surakarta City in 2006-2023. This study uses an associative quantitative approach and the method used is multiple linear regression processed with the help of STATA 13. The results showed that population and government expenditure have a positive and significant effect on local revenue. Simultaneously, both variables have a significant effect on local revenue in Surakarta City.
Effect of Humic acid and levels of Zinc and Boron on Chemical Behavior of Zinc in Calcareous Soil
Authors: Mahmoud Odah Marwan , Makki Naser Kadhim
Published: September 2024

There are global concerns about the significant increase in the concentrations of heavy elements due to the increase in agricultural, urban and industrial activities, which poses a threat to the natural environment and humans. This study focused on studying the addition of humic acid and different levels of zinc on the presence of zinc in the soil in its different forms and its readiness for the plant to find the best concentration and with the presence or absence of humic acid. This study was carried out on the sunflower crop, as zinc was added at levels of (0, 15 and 30) kg h-1 and humic acid at two concentrations, (0 and 50) kg h-1. Zinc was extracted successively and total and available zinc was measured. The results indicated: Concentration of total and available Zinc associated with carbonate minerals, with oxides, and with organic matter in soil increased with increasing levels of Zinc added to soil, reaching 8.638, 1.049, 1.971, 1.658 and 1.625 mg kg-1 soil, respectively. The effect of added humic acid was significant in reducing the concentrations of total Zinc, Zinc bound to carbonate minerals, bound to oxides and residues. The maximum concentrations in case of not adding acid reached 9.313, 1.8957, 1.424, and 4.300 mg kg-1 soil, respectively, while the effect was positively in increasing available concentration associated with organic matter, as concentration in case of adding humic acid reached 0.851 and 1.4584 mg kg-1 soil, respectively. In the case of adding humic acid, this study is considered good for the results it showed in increasing the available zinc with the presence of humic acid, which is reflected in the plant growth and maintaining this element within the recommended concentrations. We determined Zn speciation in the soil system and evaluated the effects of humic acid application on the basic soil properties and Zn bioavailability.
The role of business forums in the exchange of experience and professional development of real estate professionals
Authors: Vladislav Ryabov
Published: September 2024

This study examines the role of business forums in facilitating knowledge exchange and professional development among real estate specialists. Employing an integrated theoretical framework based on knowledge management, social capital, and andragogy concepts, the research analyzes the specific mechanisms through which business forums contribute to skill development, network expansion, and market adaptability. The study utilizes a comprehensive literature review and conceptual analysis to identify key forum formats and their effectiveness. Findings reveal that business forums serve as multifaceted platforms for professional growth, offering benefits such as access to current industry trends, expert knowledge, and networking opportunities. However, limitations including knowledge fragmentation and selective participation are also noted. The research contributes to the understanding of informal learning in the real estate sector and provides practical recommendations for maximizing the efficacy of business forums in professional development strategies. This novel approach bridges theoretical perspectives with practical industry applications, offering insights for both academics and practitioners in the field.
Drilling towards decarbonization: Sustainable fluid solution for Vietnam
Authors: Muhammad Ahsan  , Aaron Gobe
Published: September 2024

Embarking on a journey toward sustainable drilling practices, an operator in Vietnam faced the challenge of drilling high-pressure/high-temperature (HP/HT) wells through a reactive formation. In pursuit of environmental excellence and emissions reduction the operator collaborates with Baker Hughes to develop a tailored drilling fluid solution. Key objectives of sustainable drilling fluid design included maintaining downhole stability, ensuring wellbore integrity, and meeting environmental regulations. A multidisciplinary team developed a tailored drilling fluid solution comprising the PERFLEX™ high-performance water-based drilling fluid system in combination with the PYRO-DRILL™ water-based drilling fluid. This paper will highlight the solution supported by additional WBM additives, exceeded expectations, enabling the operator to drill the well 14 days ahead of plan, resulting in estimated savings of $4.2 million USD. The drilling operation resulted in a reduction of emissions by 21%, contributing to the operator's sustainability targets. The successful execution of the drilling operation demonstrated the efficiency and reliability of the HPWBM fluid program, contributing to reduced operating time, lower costs, and minimal environmental impact compared to previous drilling campaigns. This case study underscores how high-performance water-based mud systems can optimize drilling operations, reduce waste, and provide an economical approach to drilling HP/HT wells in Vietnam, aligning with sustainability and carbon reduction goals.
Postpartum depression and its risk factors: A review
Authors: S. SHRIBALAJI  , S. VAISHNAVI  , A. J. SHARU LATHA BINU  , M. RAJKUMAR
Published: September 2024

Postpartum depression is a prevalent health disorder which affecting women’s mental condition during the postnatal period, characterized by mood swings, anxiety, and depressive symptoms. PPD is a complex condition influenced by a combination of biological, psychological, and social factors. It can lead to significant adverse outcomes for both mothers and infants if not identified and managed promptly. Various biological, psychological, and social factors contribute to the onset of PPD, including hormonal fluctuations, genetic predisposition, prenatal anxiety, and lack of social support. Understanding these risk factors is essential for early diagnosis and effective intervention. This study conducted a comprehensive review of existing literature to identify the primary risk factors associated with PPD. The analysis included data from diverse populations across different countries, examining biological, psychological, and social determinants. Key studies were selected based on their relevance, sample size, and methodological rigor. The prevalence of PPD was analysed in relation to factors such as prenatal depression, caesarean section, vitamin D deficiency, and genetic markers. Additionally, therapeutic interventions like Cognitive-Behavioural Therapy (CBT), Interpersonal Therapy, and pharmacological managements were evaluated for their effectiveness in managing PPD. Early identification and intervention are critical to mitigating its impact on mothers and infants. Effective management strategies should include a combination of psychological therapies, pharmacological treatments, and strong social support systems. Public health initiatives must prioritize education, awareness, and access to mental health services to ensure timely diagnosis and treatment of PPD, thereby improving maternal and child health outcomes.
Enhancing construction site efficiency through artificial intelligence (AI)
Authors: Ruchit Parekh  , Olivia Mitchell
Published: September 2024

Artificial Intelligence (AI) is profoundly impacting productivity and economic growth across various sectors. In Malaysia, challenges related to AI in construction include limited expertise, privacy concerns, and cultural barriers on construction sites. This research aims to pinpoint key factors that influence AI's effectiveness in enhancing construction site workflows, identify obstacles in improving workflow performance, and assess the relationships between primary factors affecting AI use and the main challenges faced. The study focuses on G7, a contractor company based in Johor Bahru, employing a quantitative method to achieve its goals. The research gathered insights from 226 Grade 7 contractors in Johor Bahru through questionnaires distributed via face-to-face meetings and online forms sent through WhatsApp and email. Out of the respondents, 101 (45%) provided responses. Data was analyzed using SPSS software, incorporating descriptive statistics, frequency counts, and cross-tabulations. The study revealed that the most frequently cited factors and challenges are risk management and limited AI expertise, respectively. The strongest correlation identified was between return on investment and slow electrical supply. These findings offer valuable guidance for contractors to enhance performance, mitigate risks, and boost efficiency. This study paves the way for more targeted interventions and strategic approaches to improve construction site workflows, ultimately benefiting industry stakeholders.
Utilization of artificial intelligence in project management
Authors: Ruchit Parekh  , Olivia Mitchell
Published: September 2024

Managing projects involves intricate procedures that demand meticulous planning, execution, and oversight. Conventional methods frequently face difficulties when handling extensive datasets, unexpected issues, and repetitive tasks. Artificial intelligence (AI) provides a revolutionary approach that can enhance multiple facets of project management. This paper investigates the current applications of AI within the field. It reviews existing research on AI methodologies employed for tasks such as resource allocation, risk assessment, scheduling, cost estimation, and communication. The paper further examines the process of integrating AI into project management, covering aspects such as data gathering, model selection, and training. It also addresses possible challenges and limitations, presenting numerical evidence of AI's effectiveness in improving project results. The paper concludes with a discussion on future prospects of AI in project management and its potential influence on the discipline.
Status report on greenhouse gas emissions in lowland rice farming in Ivory Coast
Authors: Karamoko OUATTARA  , Brahima André SOUMAHORO  , Tchoa KONE  , Mongomake KONE
Published: September 2024

Rice production is a major source of global methane and nitrous oxide emissions. Numerous studies have been conducted to quantify the flux rates of these gases in rice fields in many developed countries. However, in Africa and particularly in West Africa, where this culture is experiencing considerable growth, very few studies have focused on this aspect. Thus, the objective of this review was to evaluate the studies and study methodologies already carried out on greenhouse gases in rice cultivation. It appears that several countries have quantified greenhouse gases emitted in rice cultivation. Several methods have been developed such as the gas chromatograph, the spectroscopic method and the calculation using the IPCC guidelines for the quantification of greenhouse gases in rice cultivation. The gases retained are methane and nitrous oxide. And the quantities of gas emitted vary depending on the country. Emissions in Asia are higher than those on other continents. Several emission mitigation solutions have been proposed for rice cultivation with less environmental destruction. However, most of these methods have not yet been applied.
Overview of Art Nouveau furniture decorating methods
Authors: Alevtina Grishina
Published: September 2024

This article provides a detailed overview of the methods of decorating furniture in the Art Nouveau style, which was popular in the late XIX – early XX century. This style is known for its elegance and unique aesthetic qualities, based on natural motifs, smooth lines, and asymmetry. The article explores the key decorating techniques used in the creation of Art Nouveau furniture, including wood carving, inlay, the use of glass and metal, art paintings, and mosaics. Each of these techniques is described, with an emphasis on its impact on the visual perception and functionality of furniture. Examples of works made in the Art Nouveau style are also given. The ways of integrating Art Nouveau elements into modern furniture projects are described, which emphasizes the relevance of the style and its value.
Analisis Pengintegrasian Pendidikan Mitigasi Bencana Pada Pembelajaran di Indonesia
Authors: Yani Yani , Maryani Enok , Yani Ahmad
Published: September 2024

Indonesia is a country that faces a high threat of natural disasters. The resulting losses are significant. Therefore, systematic steps are needed to analyze and reduce the factors causing disasters. Efforts to reduce disaster risks include integrating disaster mitigation education into multiple subjects and at every level of education. So far, disaster education has only been partially implemented, with only science, social studies, and geography lessons incorporating disaster content. Other subjects have not yet integrated disaster into their curriculum. This article aims to explain the integration of disaster mitigation education in schools to cultivate a generation of citizens who are aware and capable of adapting to disasters in their surroundings. The research method employed in this study is a literature review using the Population, Intervention, Comparison, and Outcome (PICO) technique. The search and selection procedures for articles in this study utilize the Preferred Reporting Items for Systematic Reviews & Meta-analyses (PRISMA) framework. The study involves an analysis of relevant sources related to the integration of disaster education. Integrating disaster mitigation education into various subjects will foster a culture of disaster preparedness, thereby minimizing the risks posed by disasters. When students are equipped to face disasters, they can develop resilience towards the disasters they encounter.
Effects of trunk control, upper and lower extremity functions on functional activity, activities of daily living and quality of life in Parkinson's Disease
Authors: Özkan Taşkın , Ateş Sarı Yasemin , Erkoç Aybike , Sücüllü Karadağ Yeşim , Ünlüer Nezehat Özgül
Published: September 2024

Purpose: To investigate the relationship between trunk control, upper and lower extremity function with functional activity, activities of daily living and quality of life in patients with Parkinson’s Disease (PwPD). Materials and Methods: The study was completed with 52 PwPD. Trunk control was evaluated with the Trunk Impairment Scale (TIS); upper extremity function with 9-Hole Peg Test (9-HPT) bilaterally; lower extremity function with 30-Second Sit-To-Stand Test (30STS); functional activity level with The Parkinson Activity Scale (PAS); activities of daily living with Barthel Index (BI); quality of life with The Parkinson's Disease Quality of Life Questionnaire (PDQ-39) Results: 30STS and right-left 9-HPT results was correlated with PAS and PDQ-39, but not with BI in PwPD. All TIS scores except the coordination sub-parameter were found to be associated with PAS, all TIS scores except the static sitting balance sub-parameter were found to be associated with BI, and all TIS scores were found to be associated with PDQ-39 in PwPD (ρ between 0.293 and 0.689; p
Pengaruh pemberian actinomycetes terhadap penurunan jumlah leukosit pada mencit diare
Authors: Claresta Ivena , Lestari Endang Sri , Anjani Gemala
Published: September 2024

Background: Diarrhea cases are mostly caused by enteropathogenic escherichia coli (EPEC).  Elevated white blood cells or leucocytes are closely associated with the incidence of diarrhea due to bacterial infection. Actinomycetes are known to have antibacterial properties that can fight pathogenic microorganisms.Objectives: To analyze of the effectiveness of Actinomycetes from the right wing of Musca domestica on leucocyte counts in EPEC-induced mice.Methods: Experimental study with randomized post-test only with control group design. This study was conducted from June to July 2023 at the Pharmacology Laboratory of Muhammadiyah Surakarta University, using 30 mice divided into 5 groups. Actinomycetes intervention was given equivalent to 0,5 McFarland standard with dose variations:  0,26ml/20gBW (group P1), 0,65ml/20gBW (group P2), and 1,3ml/20gBW (group P3). EPEC induction was 0,5ml orally in the treatment group and negative control group (KN).  The healthy control group (KS) was given 0,5ml of mineral water. The variable measured was the number of leucocytes of Mus musculus mice taken on the third day after the intervention. Data processing was performed using the Kruskall-Wallis Test to determine differences between groups with level significantly p<0,05.Results: There was a decrease in the leucocytes counts in the treatment group compared to the KN group (p=0,027). The highest mean leukocyte count was seen in the KN group (8.786,7 mm3) while, the lowest mean leukocyte count was in the P2 group (6.48,3 mm3).Conclusion:  Actinomycetes intervention in EPEC-induced diarrhea mice effectively reduces leucocyte counts.KeywordActinomycetes, Leukocyte, Diarrhea
Hubungan kualitas diet dengan kejadian stunting pada anak 2-5 tahun di Kota Bengkulu
Authors: Sabilla Imelda , Simanjuntak Betty Yosephin , Wahyu Tetes
Published: September 2024

Background: The quality of children's diet needs attention because it is often low in the nutrients needed to support growth. This means that the practice of poor quality diet given to children will provide an opportunity for stunting to occur.Objective: This study aims to determine the relationship between diet quality and the incidence of stunting in children aged 2-5 years at the Sawah Lebar Community Health Center, Bengkulu City in 2023.Method: Observational research with a cross sectional approach was conducted on 54 mothers of toddlers at the Sawah Lebar Community Health Center, Bengkulu City in May-June 2023. Sampling used a simple random sampling technique. The instrument of this research is the SQ-FFQ (semi quantitative food frequency questionnaire) questionnaire by asking about food ingredients consumed in the past month. Diet quality is divided into 4 categories, namely variety, adequacy, moderation and balance. Diet quality is low if less than ≤60 and height >60. The test used is the chi-square test with a significance level of α=0,05.Results: The results of this study show high levels of varied consumption and low levels of adequacy, moderation and overall balance that the majority (54,7%) have low diet quality. In contrast to the incidence of stunting, it shows that the majority (77,8%) have normal nutritional status (HFA). There is no relationship between diet quality and the incidence of stunting in children aged 2-5 years at the Sawah Lebar Community Health Center, Bengkulu City (p= 0,084).Conclusion: The majority of children have low diet quality, however the majority have normal nutritional status (HFA). The quality of diet in toddlers is not related to the incidence of stunting in children aged 2-5 years at the Sawah Lebar Community Health Center, Bengkulu City.
Pengaruh sosialisasi tentang keamanan pangan terhadap skor keamanan pangan pada warung bubur kacang hijau (BURJO) di Tembalang Semarang
Authors: Abduh Setya Budi Muhammad , Irvan Bagaskara , Mulyani Sri , Pramono Yoyok Budi , Nurwantoro Nurwantoro , Kamil Rafli Zulfa
Published: September 2024

AbstractBackground: Food safety is an important factor in maintaining human health. The more aware people are of food safety, foodborne diseases or diseases transmitted through food can be suppressed. The number of Burjo stall users is not yet known whether it is accompanied by awareness about food safety. One of the keys to food safety is maintaining hygiene and sanitation, so it is necessary to socialize food safety in Burjo stalls.Objective: To assess the impact of food safety campaigns on Burjo stalls in the Tembalang area of Semarang, as evaluated by food safety scores and total microbial counts.Method: Surveys, observations, and interviews were conducted at 5 Burjo stalls to obtain data on food safety scores (FSS). Samples of fried tempeh were also collected to test for microbial contamination using the total plate count method at the Food Microbiology Laboratory, Faculty of Animal Husbandry and Agriculture, Diponegoro University, Semarang. The entire study spanned three months, from June  to August 2023. Following the initial survey, food safety campaigns were conducted twice on the 2nd and 15th days, accompanied by the provision of personal protective equipment for food handlers. Subsequently, a follow-up survey was conducted to gather comparative food safety data.Results: The food safety score before and after food safety socialization was 0,862 and 0,939, while the microbial contamination (CFU/g) was 2,18x104 and 1,31x104. Food safety score increased by 8,96% while microbial contamination increased by 112,41% but still within the safe consumption threshold.Conclusion: Food safety socialization accompanied by the provision of simple personal protective equipment for food handlers in Burjo stalls is effective in improving food safety status and the category of safe consumption.
Acompanhamento farmacoterapêutico de pacientes oncológicos em cuidados Paliativos durante a internação hospitalar
Authors: LIMA Victoria Mendes , BRASILEIRO Luana Amaral , MELO Raí Martins , OLIVEIRA Livia Costa , MATTOS Luciana Favoreto
Published: September 2024

Objetivo: Analisar os Problemas Relacionados a Medicamentos (PRM), e as intervenções farmacêuticas realizadas a partir do acompanhamento farmacoterapêutico dos pacientes com câncer, internados em uma unidade de cuidados paliativos exclusivos, em um instituto de referência no Rio de Janeiro. Método: Foi realizado um estudo observacional, descritivo, retrospectivo, com abordagem quantitativa. A população consistiu em pacientes internados e em acompanhamento farmacoterapêutico no período de junho de 2022 a maio de 2023. Os dados foram coletados de prontuários físicos, sistemas institucionais eletrônicos e planilhas específicas. Foram analisadas variáveis sociodemográficas, clínicas e farmacoterapêuticas. Resultados: Foram avaliados 283 pacientes, entre 21 e 85 anos de idade, cuja maioria possuía 60 anos ou mais (n=153; 54,1%; idade média = 60,1; desvio padrão = 8,2) e pertencia ao sexo feminine (n=186; 65,7%). O sítio tumoral primário mais frequente foi do aparelho digestivo (n= 56; 19,8%) seguido por mama (n= 55; 19,4%) e ginecológicos (n= 55; 19,4%). Em relação às comorbidades, a maior parte dos pacientes apresentou pelo menos uma (n= 166; 58,7%), sendo o sistema circulatório (n= 121; 42,7%) o predominante. A porcentagem de pacientes que apresentou PRM foi de 50,9% (n= 144). Observou-se 298 PRM, dentre os quais foi destacada a não utilização do medicamento necessário ao paciente (n= 106; 35,6%). Foram realizadas 302 intervenções no total, principalmente em relação à inclusão de um novo medicamento (n= 87; 28,8%). Houve 93% de aceitabilidade das intervenções realizadas. Conclusão: A atuação clínica do farmacêutico na equipe multiprofissional possibilita a identificação dos PRM contribuindo, então, para o uso racional e seguro dos medicamentos, por meio da otimização da prescrição e racionalização da farmacoterapia.
Effects of different doses of zeatin, kinetin, and gibberellic acid biostimulants on growth and biochemical parameters during the seedling development stage of Istanbul Oregano (Origanum vulgare L. ssp. hirtum)
Authors: Yolcu Muhammed Said
Published: September 2024

This research was conducted to determine the effects of different doses of zeatin, kinetin, and gibberellic acid biostimulants, which are plant growth and development regulators, on the growth parameters and some biochemical parameters of Istanbul oregano (Origanum vulgare L. ssp. hirtum). The experiment was carried out in a greenhouse setting according to the "Completely Randomized Experimental Design" with three replications. In the study, seedling and root lengths, seedling and root fresh weights, seedling and root dry weights, chlorophyll a, chlorophyll b, total carotenoid content, total phenolic content, and antioxidant activity (CUPRAC and FRAP) parameters were examined. The results of the study showed that all biostimulants increased the growth and biochemical parameters compared to the control, except for seedling dry weight. The highest plant height was obtained from the 200 ppm dose of gibberellic acid, while the highest values in growth parameters, except for root dry weight, were obtained from the 50 and 100 ppm doses of kinetin. The highest values for chlorophyll a, total chlorophyll, total carotenoid, and FRAP antioxidant activity were found at the 40 ppm dose of zeatin, while the highest values for total phenolics and CUPRAC antioxidant activity were observed at the 100 ppm dose of kinetin.
DEVELOPMENT AND IN-VITRO ASSESSMENT OF DIVALPROEX SODIUM BILAYERED TABLETS
Authors: Gunda Dr. Raghavendra Kumar , Kolli Dr Tirumala Devi
Published: September 2024

Objective: The aim of the current research work is to develop a bi-layered Divalproex sodium tablet with an immediate release layer and a sustained release layer. Divalproex sodium is regarded as the most significant antiepileptic medication and is frequently used to treat bipolar illness, epilepsy, and migraine prevention.
Methods: Wet granulation was used to prepare both (Immediate release, Sustained release) layers since Divalproex had poor flow properties. Superdisintegrants were used to produce the immediate release layer, which was then assessed for physical characteristics, disintegration time, and in-vitro drug release.
Results: For the bi-layered tablet formulation, the optimal immediate release layer (IF6) with the maximum in-vitro release of 98.11 was chosen. Along with in vitro drug release tests, HPMC-K4M and HPMCK100M polymers were utilized in varying amounts and combinations to delay the release of the drug from the sustained release layer. The polymers were also assessed for physical parameters. The Divalproex sodium release is prolonged for more than eighteen hours by the optimized sustained release layer (SF8). Ultimately, Divalproex sodium's chosen sustained release layer and immediate release layer were twice compressed to create bi-layered tablets. The tablets were assessed for their in-vitro drug release, consistent drug content, friability, thickness, hardness, and weight variation. Every physical parameter fell within the pharmacopeial specification's permitted range.
Conclusion: The best formulation (SF8) contained 26.25 mg of HPMC-K4M and 26.25 mg of HPMC-K100M  showed promising results for obtain desired drug release (>90%) after 18 h and may produce patient compliance by means of reducing dosing frequency and provide chronotherapy for effective management of Epilepsy.
The Impact of Hyperemesis Gravidarum on Fetal Development and Birth Outcomes: A Systematic Review and Meta-Analysis
Authors: Liu Dan , Zhou Kunyan
Published: September 2024

Background: Hyperemesis gravidarum (HG) is a condition characterized by severe nausea and vomiting experienced during pregnancy, with an incidence rate estimated to affect between 0.3% and 2% of pregnant individuals. As HG results in prolonged periods of maternal starvation and multiple nutritional deficiencies, it can potentially disrupt the delicate balance of nutrients and metabolic processes required for optimal fetal growth and development. This systematic review aims to analyze the impact of HG on fetal development and birth outcomes. Methods: The following databases were searched from January 2000 to March 2024: PubMed, Web of Science, Science Direct, Medline (Ovid), and Embase (Ovid). The search focused on HG and its pathogenesis, treatment, fetal development, and pregnancy-related adverse outcomes. Results: 6 out of 907 studies were included which focused on HG with fetal development and birth outcomes. All 6 studies were cohort studies and the quality was high. Meta-analysis revealed that HG is associated with an increased risk of preterm birth (odds ratio (OR): 1.2; 95% confidence interval (95% CI): 1.17–1.23) and small for gestational age (SGA) (OR: 1.30; 95% CI: 1.22–1.40). Conclusions: A limited number of studies have investigated the effects of HG on fetal development and birth outcomes. The present systematic review indicated an increased risk of preterm birth and SGA associated with HG; however, high heterogeneity among the limited included studies should be noted.
The Effect of Folic Acid Supplementation in the First Trimester of Pregnancy on Perinatal Outcomes: A Retrospective Cohort Study
Authors: Korucu Dilay Gök , Dirican Aylin Önder
Published: September 2024

Background: The purpose of this study is to compare the perinatal outcomes of pregnant women who received folic acid (FA) supplements to those who did not, using a large sample size. Methods: This study was conducted retrospectively at Konya Training and Research Hospital between 2016 and 2020. The study included pregnant women who took FA and those who did not. We obtained sociodemographic data and perinatal outcomes of all pregnant women from the electronic record system. We learned about folic acid usage from the e-prescription tracking system. Results: Out of the total sample size of 2393 patients, n = 861 (35.97%) received FA supplements during pregnancy, while n = 1532 (64.02%) did not. The gestational age at birth in the group receiving FA was higher than in the group not receiving FA (271.59 ± 13.83 days vs. 270.09 ± 15.27 days, p = 0.005). The group that did not take FA had more neonatal intensive care unit (NICU) admissions than the group that did (5.09% vs. 2.90%, p = 0.011). In the group that took FA, there were n = 17 (1.97%) patients with gestational diabetes (GDM), whereas in the group that did not use FA, there were n = 15 (0.98%) patients with GDM (p < 0.001). Conclusions: The group taking FA supplements had a higher gestational age at birth and GDM, while admission to the NICU were lower compared to the group not taking FA supplements.
Low-Fat Diet Alleviates Perimenopausal Symptoms by Reducing Methylation Levels of PDE4C and NPAS2 Genes: A Randomized Controlled Trial
Authors: Zhong Xiaoling , Liu Ke , Zhao Laigang , Lei Xue , Xu Mei , Yang Lin
Published: September 2024

Background: Perimenopausal syndrome (PMS) significantly impacts the quality of life in women during the perimenopausal phase. Despite being the primary treatment, hormone replacement therapy has notable limitations. Consequently, dietary interventions, particularly low-fat diets, have garnered international attention as an alternative. Methods: The prospective Randomized Controlled Trial (RCT), approved by the Ethics Committee of the Affiliated Hospital of Guizhou Medical University, enrolled 62 perimenopausal women. Participants were divided into two groups: a low-fat diet group and a menopausal hormone therapy (MHT) group, with interventions lasting eight weeks. Both groups underwent assessments for perimenopausal symptoms, lipid profile, and oxidative stress markers, including superoxide dismutase (SOD), malondialdehyde (MDA), and reactive oxygen species (ROS), before and after the interventions. Additionally, DNA methylation levels of the PDE4C and NPAS2 genes were measured in 10 women from the low-fat diet group before and after the intervention. Results: Both the low-fat diet and hormone supplementation improved specific perimenopausal symptoms, reduced specific lipid levels, and had a positive effect on oxidative stress markers. The low-fat diet proved more effective than hormone replacement in improving the serum lipid profile and also resulted in reductions in methylation at specific sites of the PDE4C and NPAS2 genes. Conclusions: A low-fat diet may alleviate perimenopausal symptoms, lower lipid levels, and alter gene methylation sites. Clinical Trial Registration: The study has been registered on https://www.chictr.org.cn/ (registration number: ChiCTR2400084007).
Interleukin-31: The Inflammatory Cytokine Connecting Pruritus and Cancer
Authors: Akhtar Sabah , Ahmad Fareed , Alam Majid , Ansari Abdul Wahid , Uddin Shahab , Steinhoff Martin , Buddenkotte Joerg , Ahmad Aamir , Datsi Angeliki
Published: September 2024

Interleukin 31 (IL-31) is a proinflammatory cytokine, mainly secreted by Type II helper T cells. It signals through a heterodimeric receptor complex composed of IL-31 receptor α and oncostatin-M receptor β chain. The hallmark feature of IL-31, in its pathological role, is its ability to induce pruritus in mammals. Pruritus is a common symptom and major reason of morbidity in cancer patients, compromising their quality of life. Although, IL-31 is differentially expressed in different tumor types and could promote or inhibit cancer progression, high expression of IL-31 is a contributing factor to advanced stage tumor and severity of pruritus. The simultaneous existence of pruritus and cancer could either result from the aberrations in common proteins that co-exist in both cancer and pruritus or the therapeutic treatment of cancer could indirectly induce pruritus. Although the biology of IL-31 has predominantly been described in skin diseases such as atopic dermatitis and other inflammatory diseases, the precise role of IL-31 in the tumor biology of different cancer types remains elusive. Herein, we summarize the current understanding on the role of this cytokine in the pathogenesis of different cancers.
XXIX Russian National Fedin’s Conference
Authors:   Vladimir Dal State Museum of the History of Russian Literature, Kravchenko Tatyana
Published: September 2024

The scientific conference “The First World War and the 1917 Revolution in Russian Culture. On the centenary of K. Fedin's novel “Cities and Years” took place as part of the XXIX Fedin Readings in Saratov on February 28–29, 2024. The conference was hosted by the Saratov State Fedin Museum. The conference was attended by literary critics, historians and art historians of the Saratov State University, the Institute of World Literature of the Russian Academy of Sciences, the Institute of Russian History of the Russian Academy of Sciences, the State Archive of the Russian Federation, the Moscow State University, the Vyatka State University, the State Literary Museum, the Saratov State Art Museum and, of course, the staff of the State Fedin Museum. The purpose of the conference was to explore the understanding of the First World War and the Russian Revolution in the works of art of contemporaries and to analyze the influence of literature and art of the 1920s on the history of Russian culture. The reports examined problems of the history of writing and publishing literary works and the innovation of their poetics, showed the influence of avant-garde trends on the creativity of writers of the 1920s, introduced new archival materials and ego documents from the collections of the K.A. Fedin State Museum and from the N.N. Myasoedov Foundation of the State Archive of Saratov region. Despite the century that has passed since the publication of K. A. Fedin's novel and other works analyzed by the speakers, the controversy and discussions that arose after almost every report prove that the problems raised in these works are relevant today. The wide range of participants in the conference contributed to the expansion and strengthening of ties between academic science and the museum community, and the involvement of students and postgraduates of the Saratov University stimulated the interest of young people in such events.
Global inequality in environmental conditions underpinning human rights
Authors: Zulueta Naia Ormaza , Mehrabi Zia
Published: September 2024

In July 2022, the United Nations General Assembly adopted a resolution recognizing the human right to a clean, healthy, and sustainable environment. This milestone achievement integrates environmental law and human rights under a unified framework, one that aims to address environmental injustices globally. Here we assess the likelihood of an individual being exposed to combinations of five environmental conditions which underpin human rights in the UN framework – clean air, safe water, safe climate, healthy and sustainably produced food and healthy biodiversity and ecosystems. Globally we find locations with a disproportionate frequency of multiple poor environmental conditions that exceed expectations based on population size. We also analyse inequalities within countries and find that, first, populations inhabiting Indigenous lands and Persons of Concern (such as refugees, internally displaced persons), face a higher likelihood of poor environmental conditions than people not falling into these groups; and, second, that wealthier areas experience better conditions than poorer areas within countries across the majority dimensions, with the exception of biodiversity which is higher in poorer areas within nations. While each nation must determine its own pathway for realizing environmental rights for its population, these results show that an immediate focus for policy should be on assessing and reducing the inequality in the environmental conditions on which environmental rights are based so that multiple rights relating to clean air, safe water, safe climate, healthy and sustainably produced food and healthy biodiversity and ecosystems can be realized globally.