bluuebunny/crossref_metadata_2025 huggingface dataset:
Potential Fraud Detection Analysis of Finansial Statements: Diamond Fraud Approach
Authors: Fadli Nodeski Yogi , Junaidi Junaidi
Published: August 2022

The motivation of this research is the existence of fraud that occurs in the financial reporting of entities both abroad and in Indonesia. This investigation aims to explain the detection of financial statements that have the potential to contain fraud using the Fraud Diamond approach. The sampling method in this research is purposive sampling for companies listed on the Indonesia Stock Exchange. The sample consists of 93 companies during the 2017-2019 financial statement period from the manufacturing industry. The analysis of research is a multiple linear regression model with a quantitative approach. Based on statistical studies, the financial target variable significantly positively affects the potential for fraud. External pressure has a significant negative effect on the potential for financial fraud. In contrast, financial stability, the nature of the industry, effective monitoring, rationalization, and capability have no effect on the potential for financial fraud.
CUTANEOUS MANIFESTATIONS OF DIABETES MELLITUS OBSERVED IN URBAN HEALTH CARE
Authors: Sharada R.G. , A Thillaikarasi. , nan R.Sathyanaraya
Published: August 2022

Background: Aim:Skin involvement in Diabetes mellitus is very common and occurs in 43-66% of diabetics. To study the cutaneous
manifestation in patients with diabetes mellitus attending Dermatology OPD at Saveetha Medical College. Seventy-ve patients withMethod:
diabetes mellitus and having skin problem at Saveetha Medical College were included in this study. Clinical details regarding age, sex, duration of
diabetes, mode of treatment for diabetes and detailed dermatological examination were done in all the patients. Patients having skin changes
secondary to pregnancy were excluded in this study. An informed consent was taken from all the patients. The most common cutaneousResults:
manifestations observed in our study were infections (87%) followed by acanthosis nigricans (42.6%) and skin tags (29.3%). EarlyConclusion:
detection of skin manifestations in diabetes mellitus is important as to avoid or properly manage the complications and to prevent disability.
A CASE REPORT AND LITERATURE REVIEW: PRIMARY CARCINOMA OF LACRIMAL GLAND TREATED WITH ADJUVANT CHEMO- RADIATION.
Authors: S Thamizholi , T Kannan , Kalita Lachit , Chourasia Ranu
Published: August 2022

Primary Sebaceous Carcinoma of Lacrimal Gland, possibly arising from heterotopic sebaceous tissue, is extremely rare and must be differentiated
from secondary invasion of the Orbit by a primary Eyelid tumor/metastatic spread from other areas of the body. It is known to be aggressive So,
delay in diagnosis can increase the chance of local recurrence and metastasis. In this article we report a case of Primary Sebaceous Carcinoma of the
lacrimal gland, who underwent surgery with positive margin received Adjuvant radiotherapy in our Institute. A 55-year-OldCASE REPORT:
Lady presented with Left eyelid swelling. MRI ORBITS & PNS reveals malignant mass of approx. 4.3 X 3.8 cm size in superior & temporal aspect
of the left Orbit arising from the left upper eyelid compressing left globe and inseparable from the left lacrimal gland with approx. 2.3X 1.5 cm sized
enlarged left Pre- auricular Node. No optic nerve encasement, Orbital wall Destruction & Extension to adjacent paranasal sinuses is seen. CECT
Thorax & Whole abdomen – Normal. FNAC from eyelid swelling & Pre- Auricular Node S/o Sebaceous Carcinoma with metastasis. Patient
underwent left Orbital Exenteration + left supercial parotid split skin graft. HPE show the tumor mass of size 4.5 X 4X 3 cm, completely replacing
tarsal plate of eyelid & tumor mass show a highly inltrative malignant tumor with morphology consistent with sebaceous carcinoma with positive
margin and tissue from left parotid show inltration by the sebaceous carcinoma (Possibly metastasis to the Intra-parotid node with extra nodal
extension). Patient received Adjuvant/post op Chemoradiation 60 Gy/30#/ 6weeks/Rapid Arc technique with weekly 6 cycles chemotherapy Inj.
Cisplatin. Patient requires close monitoring for any sign of recurrence / Distant metastasis. A Rare case report of sebaceousCONCLUSION:
carcinoma of the Lacrimal Gland which requires appropriate evaluation & management for better prognosis.
PROSTHODONTIC REHABILITATION OF A SIX-YEAR-OLD CHILD WITH ANODONTIA AND HYPODONTIA WITH AN ASSOCIATED NON-SYNDROMIC DEFECT.
Authors: Sarah George Remin , K Nandakumar , Razak P Abdul
Published: August 2022

Edentulism has a series of detrimental effects on oral and overall health. Oral repercussions include the well-known residual ridge resorption, as
well as impaired masticatory ability, an unhealthy diet, social limitations, and poor oral health quality of life. Pre-schoolers with edentulism with
complete dentures are uncommon, although they do exist. When this unusual ailment is combined with cleft lip and palate, the situation becomes
much more difcult. Since this is a rare condition, the growing child's condence is negatively affected when he/she is compared to other
youngsters of similar age groups. Hence, it is the responsibility of a clinician to give them better treatment that will enable the child to grow up in a
healthy and happy environment. In such conditions, the most appropriate treatment of choice for a developing child is a removable prosthesis.
Removable denture prostheses contributed immensely to the eld of prosthodontics. This is a case report of prosthetic rehabilitation of a 6-year-old
child with anodontia on the maxillary arch and hypodontia on the mandibular arch associated with cleft lip and palate.
Health Inequalities in the Elderly with Different Socioeconomic Status in China
Authors: Cai Duanying , Lai Xuehua
Published: August 2022

This study aims to examine socioeconomic inequalities in health status and health service of the elderly in China to provide basis for health promotion. The data of China Health and Retirement Longitudinal Study (CHRLS) in the year 2015 was used. Adults aged 60 and over (n=8001) were included in the analytic sample. Socioeconomic status (SES) of the elderly was assessed by annual per capita consumption expenditure, education, and regional and rural/ urban status. Health status was measured by self-rated health, activities of daily living (ADL), the prevalence rate of chronic diseases and the 1-month prevalence rate; while health service was measured by the utilization of both outpatient service and inpatient service. Overall, the elderly with higher economic level had better health status and higher ADL disability rate, but lower prevalence rate of chronic diseases, 1-month outpatient visit rate and annual hospitalization rate. The elderly with lower education level had higher self-rated "poor" health, ADL disability rate, 1-month prevalence rate and 1-month non-visit rate. The elderly in eastern region or urban areas had better health status than those in central and western regions or rural areas. However, for health service utilization, the elderly in western region used both outpatient and inpatient services more frequently. The rural elderly had higher 1-month outpatient visit rate, while the urban elderly had higher annual hospitalization rate. Socioeconomic inequalities in health existed in Chinese elderly. To promote health equity among the elderly, the government should improve health insurance and medical assistance policies, optimize health resources allocation, and narrow economic gaps between western and eastern regions, and between rural and urban areas.
Antibiotics Sensitivity of Bacterial Strains Isolated From Cold Meat in Saudi Markets
Authors: Al-Masabi Saif , Abdullah Abdullah F. , Al-Sarraj Faisal
Published: August 2022

The objective research works on cold and ready-to-eat meat products from local markets and how they are affected by external factors and the transmission of microorganisms to them and their reproduction despite their preservation, despite the preservation of these meats in consumers' refrigerators, and how some of these microbes are pathogenic or cause diseases by excreting toxins. The result of our research centers on displaying the total number of bacteria in all samples, identifying the strain contained in these ready-to-eat meats, and comparing them with the permissible limits imposed by most food and drug authorities in the world to preserve the safety of consumers. Also, we test the microbes' sensitivity to antibiotics. The types of bacteria were identified through approved protocols. The total count of bacteria was not in the range of the FDA limits rate, and we found some strains that should not be in the product as E. coli and Salmonella. spp. These strains can cause severe gastrointestinal tract diseases. The results of the Antibiotic test were positive. Only two of the 30 species we identified were resistant to all the antibiotics we used. They were S. aureus. The microbiological quality of cold meats in Jeddah, Saudi Arabia, is barely within the limits of the FDA. In terms of coliforms, Staphylococcus, and streptococci. So, all the food handlers should receive training to increase the level of hygiene in the supermarkets in Jeddah, Saudi Arabia.
Microcrystalline Cellulose from Jute Fiber: A Bright Prospect for Pharmaceutical Industry
Authors: Islam M. Nurul , Hossain S.M. Mahruf , Khatton A. , Rahman M. M. , Sarker J. , Sikder H. A. , Chowdhury A. M. Sarwaruddin
Published: August 2022

Synthesis of microcrystalline cellulose (MCC) from jute sticks has been studied and reported in this work. The successful removal of lignin and hemi-cellulose has been confirmed through Fourier Transform Infrared (FTIR) spectroscopic technique. X-ray Diffraction (XRD) technique has been used to measure the crystal size and crystallinity index. The FTIR analysis revealed that the acid hydrolysis had an effect on the crystalline of the fibre; however it did not influence the chemical components of the fibres. Pharmaceutical standard tests were done. Higher concentration of sodium chlorite produces minimum particle size and the effective thermal degradation occurs at 340 °C.
Ebola: uma ameaça à Saúde Pública e à fauna silvestre
Authors: Alberto Manso Raimundo da Rocha Jorge , Sousa Reis David , Do Carmo Santos Gabriella , Nunes de Souza Isabelle , Dias dos Santos Juliana
Published: August 2022

Este artigo de revisão sumariza conhecimentos sobre a sintomatologia, patogenia, fatores epidemiológicos para algumas espécies da fauna silvestre acometidas pela virose, lista espécies silvestres vulneráveis à doença do vírus Ebola (EVD) e espécies de animais domésticos não vulveráveis, evidencia o uso de modelos animais para estudos objetivando a defesa de humanos e de animais contra essa doença e destaca a ameaça à saúde dos animais silvestres representada pela EVD.
Hybrid Cascaded Inverter-Based Integrated Hybrid Power Supply Using Nonconventional Energy Sources
Authors: Kayalvizhi S. , Senthil Kumar K. , Sindu M. , Muminthaj S.
Published: August 2022

In this research, a hybrid integrated topology that would work very well for applications involving distribution generation has been suggested. The Photovoltaic and Fuel Cell source are used to power the hybrid integrated topology's power supply. Photovoltaic source is utilized as the main power and runs very near to its Maximum Power Point, while the fuel cell section serves merely as a DC supply and feeds just the power that is needed to make up the difference. The integrated approach improves the overall power level that is supplied because of the presence of the fuel cell in parallel with the photovoltaic source. This may be achieved by smoothing out the voltage stress that are brought by the photovoltaic system's output. Another important characteristic is that the load may be fuelled by photovoltaic energy in any quantity, even if that quantity is relatively low. This is a feasible regardless of the size of the photovoltaic system. In addition, excess power may be sent to the electrolysis load, which results in the source of energy being used in the most effective manner possible. When converting voltages, a Hybrid Cascaded Multilevel Inverter (HCMI) topology is preferred over a conventional three phase inverter because it has the advantages of a gradual decrease in switching losses, a low total harmonic distortion, and a minimum power loss. This in comparison to the conventional three phase inverter, has none of these advantages. In addition to that, the voltages might be converted in a more effective way using this design. The suggested system has a number of desirable qualities, and the most notable are its low operational costs, its user-friendly layout, and its high level of durability.
Os Documentos Curriculares Nacionais e o Ensino de Ciências e Biologia
Authors: Larroyd Letícia Medeiros , Duso Leandro
Published: August 2022

O modo como o currículo é construído mostra que tipo de estudante se quer formar. Por isso, a análise curricular pode evidenciar interesses da instituição que o constrói. É importante analisar e discutir os documentos curriculares nacionais porque eles representam a base legal para a construção dos currículos nacionais. O objetivo desse trabalho foi identificar e analisar os objetivos de ensino presentes em documentos curriculares nacionais – Parâmetros Curriculares Nacionais (PCN), Parâmetros Curriculares Nacionais para o Ensino Médio e Base Nacional Comum Curricular (BNCC) dos Ensinos Fundamental e Médio – relacionados à área de Ensino de Ciências da Natureza e Biologia, através de uma pesquisa documental. Os PCN, tanto do ensino fundamental quanto do médio, trazem o “para quê” dos conteúdos, enquanto que a BNCC traz uma maior preocupação para com as competências e habilidades.
O uso de smartphones para o desenvolvimento de atividades experimentais no ensino de física
Authors: Ariston Marília Marinho , Aquino Alessandra Alexandrino , Saraiva Gilberto Dantas , Castro Antônio Joel Ramiro de , Veloso Maria Sônia Silva de Oliveira
Published: August 2022

O uso de smartphones como ferramentas experimentais oferecem uma versatilidade inspiradora para o Ensino de Física. Isso porque os sensores desses aparelhos fornecem várias possibilidades de medições. Com o objetivo de ratificar o uso de smartphones como ferramenta aliada ao processo de ensino e aprendizagem nas aulas de Física, o trabalho consistiu no compartilhamento de uma experiência de uso de smartphones durante aulas de Física do Ensino médio, realizada com alunos de uma escola pública do Ceará. A metodologia consistiu inicialmente numa pesquisa sobre sensores que podem ser aplicados para medir grandezas físicas, seleção de experimentos, realização dos experimentos durante as aulas e análise dos resultados. A partir dos dados obtidos, foi possível observar que o uso do smartphone foi eficaz na simulação de experimentos, proporcionou uma participação ativa dos alunos e medidas que trouxeram uma maior convergência entre a teoria estudada e o cotidiano do aluno.

Palavras-chave: Práticas Laboratoriais. Experimentos de Física. Smartphones. Sensores.
Formação docente durante a pandemia da COVID-19: Percepções dos/as estudantes da Licenciatura em Física sobre o Estágio Supervisionado de forma remota
Authors: Silva Aline Fuentes da , Mendes Alex Antunes , Müller Maykon Gonçalves
Published: August 2022

O presente trabalho é uma pesquisa qualitativa, básica e caracterizada como estudo de caso, de acordo com Yin (2001). O público-alvo foi formado pelos/as estudantes do último período do curso de Licenciatura em Física do IFSul - CaVG e os/as estudantes que se formaram no primeiro semestre de 2021 (2021/1). Têm-se como objetivos analisar as percepções dos/as estudantes formandos da Licenciatura em Física do IFSul - CaVG sobre os pontos positivos e negativos, bem como as adversidades experienciadas durante o estágio supervisionado obrigatório de forma remota. Os/as participantes destacaram como pontos positivos dos estágios a importância e os benefícios que a tecnologia pode trazer em uma sala de aula. Em contrapartida, os/as participantes destacaram a falta de contato presencial com os/as estudantes como o principal ponto negativo. Problemas técnicos surgiram nas salas de aula remota, principalmente com relação a desigualdade social, o que nos leva a refletir que nem todos têm a mesma qualidade e acesso a Educação. As perspectivas dos participantes são de que na pós-pandemia, avançaremos para uma abordagem híbrida, onde manteremos as vantagens do ensino remoto combinadas às vantagens do ensino presencial.
Matteo Ricci: Friendship and Chinese Christianity
Authors:   , Poon Raymond Wai-Man
Published: August 2022

In the late sixteenth century CE, Macau was a fishing village located on China' s south. Ruled by the Ming Dynasty (1368–1644), a fleet of ships had anchored in the village’s docks. China had limited foreign visitors. However, the Portuguese had arrived. The Portuguese wanted to export the European Catholic knowledge and culture to this unfamiliar land. The Portuguese colonial structure was hoping to assimilate the orient to Christianity. The Portuguese Missionary priests arrived. Matteo Ricci (1552–1610), a Jesuit priest, arrived in Macau in 1582 CE to introduce Christianity to Chinese society. At that time, Ming China followed Confucian ideology for their social guidance. Ricci realized that in order to communicate with the Chinese government officials, who held influential positions, he must learn the Chinese language and culture. Ricci gained essential communication skills from reading and translating the Four Books, which were Chinese Classics. Ricci developed friendships with some government officials by sharing his knowledge of science and technology. As his last strategy, Ricci combined European Christianity theology and Cicero’s De Amicitia. He analyzed and synthesized Confucian terminologies to write Discussion of Friendship, his foundational book. Ricci’s book contains the sole purpose of his journey: to create a movement fermented in China’s influential groups leading to the spread of Christianity. Even though Ricci did not build a physical church in China, Ricci successfully introduced Christianity to China, and laid the foundation for the European and American missionary work. He did this through friendship—gaining friends in China, earning their support, and writing Discussion of Friendship.
Sistem Informasi Desa dalam Meningkatkan Pelayanan Publik Berbasis Web Mobile
Authors: Maharani Hazira , Ulfa Maria
Published: August 2022

Kemajuan teknologi informasi saat ini ialah pemanfaatan jaringan internet yang memungkinkan setiap orang dapat mengakses atau memperoleh data-data yang tersedia secara bersama-sama melalui jaringan yang saling terhubung. Saat ini desa lesung batu masih menggunakan sistem manual dalam pelayanan, dan menyampaikan informasi kepada masyarakat. Oleh karena itu penggunaan sistem ini dalam meningkatkan pelayanan publik merupakan jalan keluar untuk meningkatkan pelayanan publik. Pembuatan aplikasi ini bertujuan untuk meningkatkan pelayanan publik dalam proses membantu masyarakat dalam mempermudah pelayanan surat pengantar dari desa. Dengan menggunakan aplikasi web mobile ini masyarakat dapat mengurus surat menyurat tanpa harus datang ke kantor desa, sehingga dapat dilakukan dimanapun dan kapanpun. Metode pengembangan sistem yang digunakan dalam hal ini adalah web engineering, yaitu model rekayasa perangkat lunak untuk mengembangkan aplikasi web. Tahapan dalam rekayasa web yaitu Communication, Planning, Modeling Construction, dan Deployment
PERENCANAAN PEMBELAJARAN MODEL PENDIDIKAN HOLISTIK BERBASIS KARAKTER PROGRAM SEMAI BENIH BANGSA
Authors: Subakat Rahayu
Published: August 2022

Penelitian ini bertujuan untuk mengetahui implementasi pendidikan holistik berbasis karakter yang fokusnya pada aspek perencanaan pembelajaran. Penelitian menggunakan metode kualitatif dengan sumber data primer dengan teknik wawancara, observasi dan dokumentasi. Temuan dari penelitian ini menjelaskan bahwa perencanaan dalam pendidikan holistik berbasis karakter bersifat kolaboratif antara pihak penyelenggara pendidikan dan seluruh stakeholder.  Metode pembelajaran yang digunakan  lebih kepada bermain dalam sentra atau tematik. Seluruh aktifitas pembelajaran mengacu pada kurikulum pendidikan holistik berbasis karakter. Hasil dari penelitian ini dapat dijadikan acuan bagi lembaga pendidikan yang akan menyelenggarakan pendidikan holistik berbasis karakter dan selain itu juga dapat dijadikan referensi bagi penelitian selanjutnya terkait pendidikan karakter yang fokusnya pada anak usia dini.
PEMBERDAYAAN PETANI AREN DI DESA TOMPOBULU KECAMATAN TOMPOBULU DALAM PEMBUATAN GULA MERAH MENJADI KOMODITAS USAHA DI ERA DIGITAL
Authors: Basri Syamsuriana , Radiah Radiah , M Anita
Published: August 2022

Desa Tompobulu merupakan desa yang terletak di kecamatan Tompobulu, Kabupaten Maros. Desa Tompobulu yaitu salah satu desa penghasil gula merah dengan potensi aren yang cukup tinggi. Tujuan dari kegiatan ini adalah untuk meningkatkan pemahaman petani aren dalam proses pengemasan dan pemasaran produk dengan menggunakan teknologi digital. Peserta pada kegiatan ini terdiri atas 3 kelompok petani aren yang masing-masing setiap kelompok petani aren beranggotakan 4 orang. Hasil dari pelatihan yang diperoleh yaitu 1) peningkatan pengetahuan dari petani aren  yang diperoleh dari hasil kuesioner oleh  peserta kegiatan sebagai responden diperoleh persentasi sebesar 61,11% dengan rata-rata persentasi pretest sebesar 31,67% dan posttest 97,78%. 2) menghasilkan produk gula merah berbagai bentuk seperti persegi panjang, bunga dan setengah lingkaran dengan kemasan yang menarik, serta produk tambahan yang dihasilkan dari kegiatan ini, yaitu produk tenteng (gula kacang), gula semut, dan gula merah cair, 3) pemasaran produk dilakukan  melalui media sosial Facebook, Whatshapp, Instagram, Blog dan/atau Website secara online (Tokopedia, Shopee, Lazada, Bukalapak, dan Tokko)  dan Pasar-Pasar Tradisional.
PELATIHAN PEMBUATAN BLOG PENDIDIKAN BAGI MAHASISWA
Authors: Nasution Awal Kurnia Putra , Batubara Muhammad Hasyimsyah
Published: August 2022

Pesatnya perkembangan teknologi informasi dan komunikasi saat ini membawa dampak positif terhadap pendidikan. Pemanfaatan blog di dunia pendidikan merupakan dampak postif kamjuan tersebut. Pengabdian pada masyarakat ini bertujuan untuk memberikan pelatihan pembuatan blog pendidikan bagi mahasiswa. Metode pelatihan menggunakan pendekatan teori dan praktek. Teori yang disampaikan terkait dengan manfaat blog pada pendidikan, praktek dilakukan dengan langsung setiap peserta membuat blog pendidikan. Pertemuan dilakukan secara daring dan luring. Secara daring dengan memanfaatkan Google Meet dan grup Whatsapp, secara luring dengan langsung bertatap muka dengan peserta. Peserta yang mengikuti pelatihan ini adalah mahasiswa dari beberapa program studi yang berbeda. Hasil pengabdian menunjukkan bahwa pelatihan ini memberikan banyak manfaat bagi peserta, seperti: bertambahnya pengetahuan terkait dengan blog, peserta mampu membuat blog yang informative dan menarik di sisi tampilan, serta meningkatkan skill peserta. Pada kesempatan mendatang, perlu diadakan pelatihan yang lebih baik dan peserta yang lebih banyak.
Pathogenesis of the obstetric antiphospholipid syndrome: the key role of beta 2 glycoprotein I
Authors: Meroni Pier Luigi , Grossi Claudia , Tedesco Francesco
Published: August 2022

Antiphospholipid syndrome (APS) is defined by recurrent pregnancy morbidity and/or vascular thrombosis associated with the persistent presence of antibodies against anionic phospholipid-binding proteins. Beta 2 glycoprotein I (β2GPI) and prothrombin (PT) are the major antigens for antiphospholipid antibodies (aPL) detectable by functional coagulation [lupus anticoagulant (LA)] or solid-phase assays [anti-β2GPI-dependent cardiolipin (aCL) and anti-β2GPI]. β2GPI-dependent aPL are responsible for the positivity of the three classification laboratory criteria. While medium/high titers of antibodies against β2GPI are risk factors for both the vascular and the obstetric manifestations of APS, persistent low titers are also associated with pregnancy complications. There is evidence from animal models of aPL-dependent fetal loss and from in vitro systems that β2GPI-dependent aPL can be pathogenic. β2GPI is physiologically found in large quantities at the placental level being available for the specific antibodies circulating in the maternal blood. Once bound to the protein, the antibodies trigger a local inflammation via the activation of the complement cascade and affect trophoblast and decidual function. The final result is represented by defective placentation, while thrombotic events are apparently less important. β2GPI is a pleiotropic molecule with scavenging properties towards several molecules including apoptotic material and displays anti-oxidant activity. These functions may explain the β2GPI placental localization in an area of intensive tissue remodeling and low oxygen tension. Since β2GPI interacts also with the complement and the coagulation cascade, its binding with specific antibodies may affect the physiology of placentation in several ways.
HIGHER ORDER BOUNDARY VALUE PROBLEM WITH INTEGRAL CONDITION AT RESONANCE
Authors: Kouidri M. , Amara A.
Published: August 2022

In this work, we prove the existence of solution for the following higher-order boundary value problem at resonance $\omega^{(n)}(t)=f(t,\omega(t),\ldots,\linebreak \omega^{(n-2)}(t))$ $n\geq 3,\, t\in (0,1),$ $ \omega(0)=\omega'(0)=\ldots =\omega^{(n-3)}(0)=\omega^{(n-1)}(0)=0,\omega(1)=\frac{n-1}{\eta ^{n-1}} \int_{0}^{\eta }\omega(t)dt;\eta \in (0,1),$ we have relied on Mawhin’s coincidence degree theory to get existence results.
Development of Tourmaline-Bearing Lithologies of the Peraluminous Tusaquillas Composite Granitic Batholith, NW Argentina: Evidence from Quartz and Tourmaline
Authors: Henry Darrell J. , Zappettini Eduardo O. , Dutrow Barbara L.
Published: August 2022

Textural and chemical characteristics of quartz and tourmaline found in tourmaline-rich orbicules, greisens, pegmatites, and tourmalinite segregations associated with the peraluminous leucogranitic Tusaquillas Batholith Complex of northwest Argentina exhibit both magmatic and hydrothermal features. Imaging of quartz by optical cathodoluminescence and scanning electron microscopy cathodoluminescence shows three stages of development. Stage-1 quartz, considered magmatic, develops as large grains in pegmatites that have optical cathodoluminescence homogeneity; as anhedral relict grains partially replaced by stage-2 hydrothermal quartz in tourmalinite segregations, orbicules, and greisens; and as idiomorphic grains with irregularly spaced oscillatory zoning seen in scanning electron microscopy cathodoluminescence in orbicules. Stage-2 quartz, interpreted as hydrothermal, partially replaces stage-1 quartz and generation-1 tourmaline in most lithologies. Stage-3 quartz, a late hydrothermal stage, occurs in all lithologies as weakly luminescing quartz in healed quartz fractures with abundant fluid inclusions, commonly associated with the crystallization of irregular late-stage tourmaline.

Multiple generations of tourmaline span magmatic to hydrothermal phases of development. In all lithologies, generation-1 tourmaline is compositionally similar: highly aluminous (range of average values of Altotal = 6.31–6.95 apfu), markedly Fe- and X□-rich (XMg = 0.01–0.17, X□= 0.21–0.51), and having variable F and WO (F = 0.00–0.57 apfu, WO = 0.00–0.40). Generation-1 tourmaline is interpreted as magmatic with compositions reflecting the chemical environment of the host lithologies and with compositional zoning patterns characteristic of both closed- and open-system behavior, possibly related to the transition to subsolidus conditions. Similar to generation-1 tourmaline, later-stage generations-2 and -3 tourmaline compositions are highly aluminous (range of average values of Altotal = 6.38–6.79 apfu), markedly Fe- and X□-rich (XMg = 0.00–0.20, X□= 0.28–0.40), and variably F- and WO-enriched (F = 0.07–0.57 apfu, WO = 0.00–0.31), but notably poorer in Ca and Ti (<0.01 apfu). The later-stage tourmaline is considered to have developed during the subsolidus hydrothermal conditions. External chemical contributions to tourmaline compositions from the country rocks appear to be minor to nonexistent. The X-site and W-site occupancies of the late-generation tourmaline implies subsolidus invasive alkaline, saline aqueous fluids with high Na but minimal Ca contents derived from the crystallizing leucogranites and related rocks across the solidus-to-subsolidus transition.
EEG evidence that morally relevant autobiographical memories can be suppressed
Authors: Satish Akul , Hellerstedt Robin , Anderson Michael C. , Bergström Zara M.
Published: August 2022

Remembering unpleasant events can trigger negative feelings. Fortunately, research indicates that unwanted retrieval can be suppressed to prevent memories from intruding into awareness, improving our mental state. The current scientific understanding of retrieval suppression, however, is based mostly on simpler memories, such as associations between words or pictures, which may not reflect how people control unpleasant memory intrusions in everyday life. Here, we investigated the neural and behavioural dynamics of suppressing personal and emotional autobiographical memories using a modified version of the Think/No-Think task. We asked participants to suppress memories of their own past immoral actions, which were hypothesised to be both highly intrusive and motivating to suppress. We report novel evidence from behavioural, ERP, and EEG oscillation measures that autobiographical memory retrieval can be suppressed and suggest that autobiographical suppression recruits similar neurocognitive mechanisms as suppression of simple laboratory associations. Suppression did fail sometimes, and EEG oscillations indicated that such memory intrusions occurred from lapses in sustained control. Importantly, however, participants improved at limiting intrusions with repeated practice. Furthermore, both behavioural and EEG evidence indicated that intentional suppression may be more difficult for memories of our morally wrong actions than memories of our morally right actions. The findings elucidate the neurocognitive correlates of autobiographical retrieval suppression and have implications for theories of morally motivated memory control.
Wieviele Nebenwirkungen verursachen die Biologika?
Authors: Gysling Etzel
Published: August 2022

Biologika, die bei entzündlichen Darmkrankheiten eingesetzt werden, sind gemäss einer Untersuchung, bei der die Behandelten regelmässig befragt wurden, häufiger als vermutet.
Blutungsrisiko bei Langzeitantikoagulation
Authors: Marty Natalie
Published: August 2022

Blutungsrisiko bei Langzeit-Antikoagulation In Leitlinien wird empfohlen, nach einer ersten tiefen Venenthrombose oder Lungenembolie die Antikoagulation unbegrenzt weiterzuführen. Eine systematische Übersicht zeigt aber, dass dabei das Risiko von schweren Blutungen gross ist.
Desinfektionsmittel: Augenrisiko beachten
Authors: Gysling Etzel
Published: August 2022

Desinfektionsmittel: Augenrisiko beachten 
 Alkohol-haltige Hand-Desinfektionsmittel, die ins Auge geraten, können eventuell Hornhaut-Läsionen verursachen. Häufig sind Kinder betroffen. Es ist wichtig, dass in diesen Fällen das betroffene Auge rasch und gründlich ausgespült wird.
Dronedaron erhöht Blutungsrisiko unter direkten oralen Antikoagulantien
Authors: Marty Natalie
Published: August 2022

Dronedaron erhöht Blutungsgefahr unter direkten oralen Antikoagulantien Bei Personen, die mit direkten oralen Antikoagulantien (DOAK) behandelt werden, kann Dronedaron (Multaq®) das Risiko von schweren gastrointestinalen Blutungen erhöhen. Dronedaron ist ein starker Hemmer des P-Glykoproteins, was zu verschiedenen ungünstigen Interaktionen mit anderen Medikamenten führt
Haut-Nebenwirkungen der COVID-Impfung
Authors: Marty Natalie
Published: August 2022

Obwohl offenbar nach einer COVID-Impfung recht häufig Hautsymptome beobachtet werden, gibt es zurzeit keine umfassende Dokumentation dazu. Neben «banalen» lokalen Reaktionen an der Injektionsstelle werden ganz verschiedene, teilweise erst nach Wochen auftretende Symptome (z.B. morbiliforme Ausschläge, Herpeszoster, Urtikaria) beschrieben, wobei ein Zusammenhang mit der Impfung nicht immer gesichert ist.
Dienogest (Monopräparat)
Authors: Marty Natalie
Published: August 2022

Mit Dienogest als Monopräparat steht eine vergleichsweise gut dokumentierte Behandlungsoption bei Endometriose zur Verfügung. Ob sich dieses Gestagen aber signifikant besser auf die Endometriose-bedingten Schmerzen auswirkt als andere Therapien (z.B. andere Gestagene), ist bisher nicht nachgewiesen.
Missbildungen wegen Metformin-Therapie des Vaters
Authors: Gysling Etzel
Published: August 2022

Wenn ein Mann während der Spermien-Entwicklungsphase (etwa die 3 Monate vor der Konzeption eines Kindes) mit Metformin behandelt wird, dann ist das Risiko von Missbildungen im Genitalbereich bei männlichen Nachkommen höher als in der Durchschnittsbevölkerung.
Schadet das Internet der Gesundheit?
Authors: Gysling Etzel
Published: August 2022

N/A
Verlust der Impulskontrolle
Authors: Gysling Etzel
Published: August 2022

Neuere Neuroleptika wie z.B. Aripiprazol (Abilify® u.a.) können wie die bei Morbus Parkinson verwendeten Dopaminagonisten zu einem Verlust der Impulskontrolle (mit Spiel- oder Kaufsucht, Hyperphagie oder Hyper-sexualität) führen.
Thyreostatika relativ gut verträglich
Authors: Gysling Etzel
Published: August 2022

In einer prospektiven Studie wurde untersucht, wie häufig das Thyreostatikum Thiamazol unerwünschte Wirkungen verursacht. Bei 25 von 208 Personen kam es zu einer Nebenwirkung meistens kutaner Natur; eine Agranulozytose oder eine hepatotoxische Wirkung wurde nicht beobachtet. Die Therapie mit Thyreostatika wird gesamthaft als gut verträgliche und kostengünstige Behandlung einer Basedow-Krankheit bezeichnet.
Development and Evaluation of a Mutual Support Program for Parents of Children with Developmental Disorders in Japan
Authors: HIRATA Yutaro , HARAMAKI Yutaka , TAKANO Yasuyo , NISHIYORI Kazuhiko , OTSUKA Rie , NAKAMURA Sae
Published: August 2022

This study aimed to develop an interaction program for mutual support exchange for the parents of children with developmental disorders, identify the most urgent issues in the program, and the potential difficulties of implementation by the qualitative method. In Study 1, practical activities were reviewed from the perspective of process evaluation for staff meetings and participant questionnaires. Program structure and intention were presented, and the innovations in program structure were described. Practical activities were discussed from the following perspectives: (1) type and content of activities; (2) duration and frequency of program implementation; (3) number and characteristics of users, characteristics of program implementers, and information on program provision methods: (i) implementation arrangements, (ii) degree of service, (iii) problems and negative effects of implementation, (iv) matching between planning and implementation, (v) stability, and (vi) utilization. In Study 2, we conducted a categorical analysis of participant questionnaires (n=157), specifically descriptive data on parents' program experiences. The effects of the program were described in three major categories: “Experiences through opportunities for reflection,” “Experiences through interaction with other parents,” and “Increased motivation.” Moreover, the contents of the program and the characteristics of the structure that produced the effects were studied. The relationship between the categories also showed the mechanism of the program's effectiveness, in which opportunities for reflection and mutual interaction among parents lead to increased motivation. In the future, it is important to examine the detailed mechanisms of the program and it is expected that further effective activities will be developed and evaluated with studies in more countries and regions.
An Albatross On the Neck: Social Media Use and Its Effects on Students’ Academic Performance in Ghana: A Comparative Study
Authors: Samuel Ameyaw , Frempong-Kore Afua , Akoto Bitherman Benedicta Krampah
Published: August 2022

This study aimed to examine social media usage and its effects on students' academic performance. The study adopted a survey design approach. The population for this study consisted of undergraduate students from two universities, thus, one private university (Valley View University – VVU) in Techiman in the Bono Region and one public university (Ghana Communications Technology University) in Takoradi, in the Western Region. The study used 5% of the population to arrive at a sample size of 381. The stratified and simple random sampling techniques were applied to select the students. A well–structured questionnaire was used as a data collection instrument. The study established that social media had negatively affected their English writing skills, which is detrimental to their academic performance. The results showed that most students visited social media platforms daily and spent more time on these platforms. The study identified challenges like; lack of personal security and privacy, poor internet services, unreliable power, the cost of internet connectivity, and many others. The study made recommendations to the management of both universities to organise workshops and seminars and educate students on the dangers of excessive use of social media platforms.
Paradigma en la Educación Superior en URUGUAY
Authors: Mendoza Graciela
Published: August 2022

República Oriental del Uruguay, es un país de América del Sur, situado en la parte oriental del Cono Sur americano. Según los datos del INE, censo de 2011, la población de Uruguay es de 3,29 millones de habitantes. Es una república presidencialista y su capital es Montevideo. Un país con un profundo impacto de mezcla multicultural guardado en su historia, desarrolla un sistema universitario casi paralelamente a la creación de la Universidad de la República a finales del siglo XIX. Con un interés importante por el desarrollo de las ciencias básicas cuyo desarrollo estuvo interrumpido por un importante periodo dictatorial durante el Siglo XX, es solo hasta casi la década de los 90 cuando verdaderamente se crea un proceso de desarrollo que obliga a este subsistema a tomar forma y crecer casi de la mano a una sociedad para quien debería generar ideas. Sin embargo a estas alturas ya era visible un sistema estatal cuyas estrategias eran carentes para el desarrollo de su educación.
Paradigma en la Educación Superior en COLOMBIA
Authors: Mendoza Graciela
Published: August 2022

Colombia, es una república unitaria de América situada en la región noroccidental de América del Sur, constituida en un estado social y democrático de derecho cuya forma de gobierno es presidencialista. Su capital es Bogotá. Aunque América Latina es una región ambigua con muchas peculiaridades en materia educativa, el caso de Colombia resulta interesante de analizar dada la forma particular en que ha evolucionado su educación superior. Un interés constante por conformar cuerpos críticos y constituir instituciones educativas de alto nivel ha sido la constante en la construcción de un soporte adecuado que permita dar respuesta a la realidad universitaria así como a encaminar al Estado a una oportuna y eficiente toma de decisiones.
Effect of Printing Orientation and Layer Thickness on Microstructure and Mechanical Properties of PLA Parts
Authors: Rahimah Abdul Hamid  , Siti Nur Hidayah Husni  , Teruaki Ito  , Barbara Sabine Linke
Published: August 2022

Due to the layer-by-layer printing process, additively manufactured objects frequently display directional dependencies in their structure. It affects the material properties of the fabricated parts concerning various process parameters of the machine. This paper presents the effect of layer thickness and printing orientation on the mechanical properties and microstructure of polylactic acid (PLA)3D printed parts fabricated by Fused Deposition Modeling (FDM). Computer-aided design models of a tensile and compression test specimen were created, conforming to the ASTM: D638 (Type 1 and Type IV) and ASTM D695, respectively. The microstructure was evaluated using a Scanning Electron Microscope (SEM) on the fracture surface during the tensile test and optical microscopy on the compression specimens. The finding shows that a low layer thickness setting contributes to the highest tensile strength in the 0° printing orientation, while a medium and high layer thickness results in a better tensile strength for a 45° and 90° printing orientation. Therefore, printing orientation is more influential than layer thickness in the tensile test. As for the compressive strength, the stress decreases when the layer thickness increases and the low layer thickness setting offers the highest compressive strength at all printing orientations. The microstructure shows more significant interlayer gaps, incomplete filling, and weak bonding on the cross-sectional samples of the fractured tensile surface with lower strength. The 0° printing orientation offers better tensile strength for all layer thicknesses, minimum build time, and good compressive strength compared to other printing orientations.
Hybrid Visual and Optimal Elliptic Curve Cryptography for Medical Image Security in Iot
Authors: Kumar L. Ashok , Srivastava Sumit , R. Balaji S. , H Shajin Francis , Rajesh P.
Published: August 2022

In this manuscript, a hybridizing visual cryptography with Optimal Elliptic Curve Cryptography is proposed for medical image security in Internet of Things (IoT). The visual cryptography is generally used to send the secure and confidential medical image to the receiver. Here, the medical image is transmitted as shares and all shares of the medical image are collectively loaded to retrieve the original medical image. Moreover, the multiple shares are created interms of pixel values of medical image and this share is extracted and partioned in blocks. The blocks of every share are encrypted with elliptic curve cryptography (ECC) mechanisms and encrypted image is decrypted using ECC decrypts. In hybridizing visual crypto with optimal elliptic curve crypto, the optimal key will be generated using an imperialist competitive algorithm. Finally, the decrypted output image compares to the original image. The proposed system is executed on MATLAB platform and performance is evaluated with existing method like Score-based Key Enumeration Algorithm (SKEA). The proposed ESEA approach reduces the file size as 45.76%, 24.97%, 15.86%, 33% and 33.86%.And higher PSNR as 29.08%, 25.86%, 23.98%, 25.86% and 42.75%. The proposed ESEA approach achieves 6.89% higher security than existing SKEA method. Furthermore, the simulation outcome demonstrates that the proposed technique can be able to find the optimal global solutions efficiently and accurately than the existing techniques.
Advances in Pituitary Surgery
Authors: Byun Yoon Hwan , Kang Ho , Kim Yong Hwy
Published: August 2022

Pituitary surgery has advanced considerably in recent years with the exploration and development of various endoscopic approaches and techniques. Different endoscopic skull base approaches are being applied to access sellar tumors in different locations. Moreover, extracapsular dissection and cavernous sinus exploration have enabled gross total resection of sellar tumors where it could not have been achieved in the past. Techniques for skull base reconstruction have also progressed, allowing surgeons to remove larger and more complicated tumors than before. This review article discusses different endoscopic skull base approaches, surgical techniques for removing pituitary adenomas, and reconstruction methods for repairing postoperative low-flow and high-flow cerebrospinal fluid leakage.
Clinical and Technical Aspects in Free Cortisol Measurement
Authors: Choi Man Ho
Published: August 2022

Accurate measurement of cortisol is critical in adrenal insufficiency as it reduces the risk associated with misdiagnosis and supports the optimization of stress dose. Comprehensive assays have been developed to determine the levels of bioactive free cortisol and their clinical and analytical efficacies have been extensively discussed because the level of total cortisol is affected by changes in the structure or circulating levels of corticoid-binding globulin and albumin, which are the main reservoirs of cortisol in the human body. Antibody-based immunoassays are routinely used in clinical laboratories; however, the lack of molecular specificity in cortisol assessment limits their applicability to characterize adrenocortical function. Improved specificity and sensitivity can be achieved by mass spectrometry coupled with chromatographic separation methods, which is a cutting-edge technology to measure individual as well as a panel of steroids in a single analytical run. The purpose of this review is to introduce recent advances in free cortisol measurement from the perspectives of clinical specimens and issues associated with prospective analytical technologies.
ORGANIZAÇÕES SOCIAIS DE SAÚDE: UM PASSO PARA A PRIVATIZAÇÃO DO SUS?
Authors: Bezerra de Melo Luciana , Oh Henry
Published: August 2022

Com o sucateamento do Sistema Único de Saúde (SUS) e a emergente necessidade de inovação na gestão da saúde pública, surgem as Organizações Sociais de Saúde (OSS). As OSS aparecem como resposta às necessidades de melhorias. Com a comercialização da saúde e o olhar mercadológico, questionase sobre: e se as OSS podem ser o caminho para a privatização da saúde pública. O presente artigo pretendeu discutir, com embasamento teórico, a partir de uma revisão bibliográfica, sobre o rumo da saúde pública no país e o futuro do SUS. A metodologia foi a busca por artigos, dos últimos 10 anos, utilizando as palavras-chaves, nas principais bases de dados. Muito ainda há que se estudar, avaliar e observar, mas entende-se a necessidade de manter a saúde comodever do estado, direito universal a todos. Conclui-se que humanização, empatia e respeito são aspectos necessários, mesmo quando se fala de gestão e administração.
Counsellor Deliberate Self-Disclosure and Therapy Seeking Behaviours among Kenyan Undergraduate Students in Kenyan Universities
Authors: Aloka Peter J.O.
Published: August 2022

The study examined the relationship between counsellor- deliberate self-disclosure and therapy-seeking behaviours among undergraduate students in Kenyan universities. The Social Comparison Theory informed this study. The study utilized the convergent parallel mixed-methods design. A sample size of 352 students was obtained using stratified random sampling. The Deliberate Self-disclosure and Intentions to Seek Therapy Inventories. The internal validity of the constructs in the questionnaires was tested by subjecting the survey data to suitability tests using the Kaiser-Meyer-Oklin measure of sampling adequacy (KMO Index) and the Bartlett’s Test of Sphericity. Cronbach’s alpha coefficient analysis was used to investigate the internal consistency of the questionnaires. Quantitative data were analysed using inferential statistics in the Pearson Correlation coefficient and simple linear regression analysis, while qualitative data was analysed thematically. The findings indicated a weak but positive correlation between counsellors’ deliberate self-disclosure and Therapy seeking behaviour (r=.140, n=352, p=008) among university students. The study recommends that university counsellors should be trained on the effective use of self-disclosure as a technique in therapy practice.