bluuebunny/crossref_metadata_2025 huggingface dataset:
DGTR: Dynamic graph transformer for rumor detection
Authors: Wei Siqi , Wu Bin , Xiang Aoxue , Zhu Yangfu , Song Chenguang
Published: January 2023

Social media rumors have the capacity to harm the public perception and the social progress. The news propagation pattern is a key clue for detecting rumors. Existing propagation-based rumor detection methods represent propagation patterns as a static graph structure. They simply consider the structure information of news distribution in social networks and disregard the temporal information. The dynamic graph is an effective modeling tool for both the structural and temporal information involved in the process of news dissemination. Existing dynamic graph representation learning approaches struggle to capture the long-range dependence of the structure and temporal sequence as well as the rich semantic association between full graph features and individual parts. We build a transformer-based dynamic graph representation learning approach for rumor identification DGTR to address the aforementioned challenges. We design a position embedding format for the graph data such that the original transformer model can be utilized for learning dynamic graph representations. The model can describe the structural long-range reliance between the dynamic graph nodes and the temporal long-range dependence between the temporal snapshots by employing a self-attention mechanism. In addition, the CLS token in transformer may model the rich semantic relationships between the complete graph and each subpart. Extensive experiments demonstrate the superiority of our model when compared to the state of the art.
On the transferability of snowmelt runoff model parameters: Discharge modeling in the Chandra-Bhaga Basin, western Himalaya
Authors: Vinze Parul , Azam Mohd. Farooq
Published: January 2023

Snowmelt runoff plays a major role in the glacierized and snow-covered basins in the western Himalaya. Modeling is the most helpful tool to quantify snowmelt contribution in mountainous rivers. However, the model calibration is very difficult because of the scarcity of ground observations in the Himalaya. We applied snowmelt runoff model (SRM) in a reference catchment of Chhota Shigri Glacier in the Chandra-Bhaga Basin, western Himalaya. Three model parameters [temperature lapse rate and recession coefficients (x and y)] among the nine model parameters were constrained using extensive field observations while initial values of other parameters were adopted from previous studies and calibrated, and the model was calibrated and validated against the observed discharge data. The daily discharge was simulated over 2003–2018 for both Chhota Shigri Catchment and Chandra-Bhaga Basin using snow cover area (SCA), precipitation, and temperature as inputs. The simulated mean annual discharges were 1.2 ± 0.2 m3/s and 55.9 ± 12.1 m3/s over 2003–2018 for Chhota Shigri Catchment and Chandra-Bhaga Basin, respectively. The reconstructed discharge was mainly controlled by summer temperature and summer SCA in the Chhota Shigri Catchment and summer SCA and summer precipitation in the Chandra-Bhaga Basin. The decadal comparison showed an increase (11% and 9%) and early onset (10 days and 20 days) of maximum monthly discharge over 2011–2018 compared to 2003–2010 in both catchment and basin scales. The model output is almost equally sensitive to the “degree day factor” and “runoff coefficient for snow” in the Chhota Shigri Catchment and most sensitive to the “runoff coefficient for snow” in the Chandra-Bhaga Basin. Though the SRM parameters were constrained/calibrated in a data-plenty reference catchment of Chhota Shigri Glacier, their application resulted in large discharge overestimation at the basin scale and were not transferable in the same basin i.e., Chandra-Bhaga Basin. Extreme care must be taken while using SRM parameters from other basins.
Multi crop high efficiency seed drill with solar hybrid seed metering: A step toward precision and sustainability
Authors: Sultan Umair , Khan Alamgir Akhtar , Husnain Syed Nabeel , Zohaib Muhammad , Hashim Norhashila
Published: January 2023

High crop production with limited energy resources is always the priority area of developing countries. Conventional agricultural experimenting and crop production methods are time-consuming, challenging, laborious, and energy intensive. Various developments and experimental studies have been carried out for advancement in agriculture technologies. This study is mainly focused on the design and development of a unique high-efficiency seed drill machine to increase the energy efficiency of agricultural experiments, and crop production and conserve the tillage, seed, fertilizer, and power requirement. This machine has a special seed dividing head and seed distributor triggered with a mechanical timer. The mechanical timer is responsible to deliver seed to the seed distributor as per fixed plotting intervals. The seed distribution unit distributes the seeds uniformly in all furrows as per the pre-decided seed rate aided with a centrifugal glider aided with a DC motor powered by a 30 W solar PV plate and backup battery. Moreover, the machine has 9 × 9 s-type spring tines for seed and fertilizer, which are mainly designed for better soil pulverization and aeration with significant in-field resource conservation as per conventional alternatives. The effective width is seven feet and adjustable rows with versatile seed rate options. Overall, the results from different field tests verified the uniform seed dispersal with improved germination rate. The analysis of power requirements compared to conventional machines results in the 40% less power requirement. Overall, the machine has customized unique features for experiments and energy-efficient precision agriculture to conserve input resources.
Clinical outcomes of proximal gastrectomy with gastric tubular reconstruction and total gastrectomy for proximal gastric cancer: A matched cohort study
Authors: Fu Jingxiao , Li Yi , Liu Xuechao , Jiao Xuelong , Wang Yuhao , Qu Hongyu , Niu Zhaojian
Published: January 2023

Background

Proximal gastrectomy with gastric tubular reconstruction is a surgical procedure that can preserve function in patients with proximal gastric cancer. However, whether gastric tubular reconstruction with proximal gastrectomy has certain advantage in some aspects over total gastrectomy is controversial. To evaluate the benefit of gastric tubular reconstruction after proximal gastrectomy, we compared gastric tubular reconstruction with total gastrectomy for proximal gastric cancer.

Method

A total of 351 patients were enrolled. Concurrent total gastrectomy patients matched with the Proximal gastrectomy group in age, sex, body mass index, clinical stage, and ASA score were selected by propensity score matching. Preoperative basic information, perioperative indicators, histopathological features, postoperative complications and nutritional status, reflux were compared between the two groups.

Results

There was no significant difference in the incidence of reflux between two groups (14.8% and 6.5% respectively, P = 0.085). There were significant differences between the two groups in bowel function recovery (2.29 ± 1.16 vs. 3.01 ± 1.22; P = 0.039) and start of soft diet (4.06 ± 1.81 vs. 4.76 ± 1.69; P = 0.047). There were no significant differences between the two groups in nutritional status one year after surgery. However, the decrease in serum hemoglobin in the TG group at 3 and 6 months after surgery was significantly higher than that in the PG group (P = 0.032 and 0.046, respectively). One month after surgery, %BW loss in TG group was significantly lower than that in the PG group (P = 0.024).

Conclusion

The Proximal gastrectomy group has better clinical outcome and gastric tubular reconstruction is simple, similar complications and reflux rates, gastric tubular reconstruction may be more suitable for proximal gastric cancer.
Effect of single spinal anesthesia with two doses ropivacaine on urinary retention after hemorrhoidectomy in male patients
Authors: Wang Lei-lei , Kang Meng , Duan Li-xin , Chang Xu-fei , Li Xiao-xin , Guo Xiang-yang , Kang Zhi-yu , Han Yong-zheng
Published: January 2023

Background

Anorectal diseases are common in the population and include internal, external, and mixed hemorrhoids. Although hemorrhoid surgery is a brief operation, anesthesia, anesthetic drugs, drug concentrations, and anesthesia level control are closely related to postoperative uroschesis. For hemorrhoid surgery, a single spinal block with ropivacaine is commonly used that blocks the S2-S4 parasympathetic nervous system, which in turn governs the voiding reflex, causing postoperative urinary retention; this affects the recovery of patients. This study was performed to investigate the effects of two doses ropivacaine that provided satisfactory analgesia and muscle relaxation and inhibited adverse reflexes on urinary retention after hemorrhoidectomy.

Methods

The study included 200 male patients who underwent anorectal surgery with American Society of Anesthesiologists (ASA) grade I–II single elective spinal anesthesia between March 2021 and March 2022. Patients were randomly assigned to 2 groups using a random number table: Group A (n = 100) received 10 mg 0.5% ropivacaine (1.5 ml 1% ropivacaine + 1.5 ml 10% glucose = 3 ml), and Group B (n = 100) received 15 mg 0.5% ropivacaine (1.5 ml 1% ropivacaine + 1.5 ml 10% glucose = 3 ml).

Results

The anal sphincter exhibited good relaxation, and no obvious traction pain or significant difference in the time of muscle strength recovery was observed between the 10 mg and 15 mg 0.5% ropivacaine groups (P > 0.05). The 10 mg 0.5% ropivacaine group had shorter time of micturition exceeding 100 ml and lower voiding International Prostate Symptom Score than the 15 mg 0.5% ropivacaine group (P < 0.01).

Conclusions

Single spinal anesthesia with 10 mg 0.5% ropivacaine not only provides satisfactory anesthetic effect for hemorrhoidectomy but also has less influence on postoperative uroschesis and is worthy of clinical application.

Trial registration

The study was registered in the Chinese Clinical Trial Registry (http://www.chictr.org.cn; identifier: ChiCTR2,100,043,686) on February 27, 2021.
Evolution of codon usage in Taenia saginata genomes and its impact on the host
Authors: Rahman Siddiq Ur , Rehman Hassan Ur , Rahman Inayat Ur , Khan Muazzam Ali , Rahim Fazli , Ali Hamid , Chen Dekun , Ma Wentao
Published: January 2023

The beef tapeworm, also known as Taenia saginata, is a zoonotic tapeworm from the genus Taenia in the order Cyclophyllidea. Taenia saginata is a food-borne zoonotic parasite with a worldwide distribution. It poses serious health risks to the host and has a considerable negative socioeconomic impact. Previous studies have explained the population structure of T. saginata within the evolutionary time scale and adaptive evolution. However, it is still unknown how synonymous codons are used by T. saginata. In this study, we used 90 T. saginata strains, applying the codon usage bias (CUB). Both base content and relative synonymous codon usage (RSCU) analysis revealed that AT-ended codons were more frequently used in the genome of T. saginata. Further low CUB was observed from the effective number of codons (ENC) value. The neutrality plot analysis suggested that the dominant factor of natural selection was involved in the structuring of CUB in T. saginata. Further analysis showed that T. saginata has adapted host-specific codon usage patterns to sustain successful replication and transmission chains within hosts (Bos taurus and Homo sapiens). Generally, both natural selection and mutational pressure have an impact on the codon usage patterns of the protein-coding genes in T. saginata. This study is important because it characterized the codon usage pattern in the T. saginata genomes and provided the necessary data for a basic evolutionary study on them.
Special Issue on Ensemble Learning and/or Explainability
Authors: Pintelas Panagiotis , Livieris Ioannis E.
Published: January 2023

This article will summarize the works published in a Special Issue of Algorithms, entitled “Ensemble Learning and/or Explainability”(https://www [...]
Automated MRI Field of View Prescription from Region of Interest Prediction by Intra-Stack Attention Neural Network
Authors: Lei Ke , Syed Ali B. , Zhu Xucheng , Pauly John M. , Vasanawala Shreyas V.
Published: January 2023

Manual prescription of the field of view (FOV) by MRI technologists is variable and prolongs the scanning process. Often, the FOV is too large or crops critical anatomy. We propose a deep learning framework, trained by radiologists’ supervision, for automating FOV prescription. An intra-stack shared feature extraction network and an attention network are used to process a stack of 2D image inputs to generate scalars defining the location of a rectangular region of interest (ROI). The attention mechanism is used to make the model focus on a small number of informative slices in a stack. Then, the smallest FOV that makes the neural network predicted ROI free of aliasing is calculated by an algebraic operation derived from MR sampling theory. The framework’s performance is examined quantitatively with intersection over union (IoU) and pixel error on position and qualitatively with a reader study. The proposed model achieves an average IoU of 0.867 and an average ROI position error of 9.06 out of 512 pixels on 80 test cases, significantly better than two baseline models and not significantly different from a radiologist. Finally, the FOV given by the proposed framework achieves an acceptance rate of 92% from an experienced radiologist.
Injectable Hydrogel Membrane for Guided Bone Regeneration
Authors: Chichiricco Pauline Marie , Matricardi Pietro , Colaço Bruno , Gomes Pedro , Jérôme Christine , Lesoeur Julie , Veziers Joëlle , Réthoré Gildas , Weiss Pierre , Struillou Xavier , Le Visage Catherine
Published: January 2023

In recent years, multicomponent hydrogels such as interpenetrating polymer networks (IPNs) have emerged as innovative biomaterials due to the synergistic combination of the properties of each network. We hypothesized that an innovative non-animal IPN hydrogel combining self-setting silanized hydroxypropyl methylcellulose (Si-HPMC) with photochemically cross-linkable dextran methacrylate (DexMA) could be a valid alternative to porcine collagen membranes in guided bone regeneration. Calvaria critical-size defects in rabbits were filled with synthetic biphasic calcium phosphate granules in conjunction with Si-HPMC; DexMA; or Si-HPMC/DexMA experimental membranes; and in a control group with a porcine collagen membrane. The synergistic effect obtained by interpenetration of the two polymer networks improved the physicochemical properties, and the gel point under visible light was reached instantaneously. Neutral red staining of murine L929 fibroblasts confirmed the cytocompatibility of the IPN. At 8 weeks, the photo-crosslinked membranes induced a similar degree of mineral deposition in the calvaria defects compared to the positive control, with 30.5 ± 5.2% for the IPN and 34.3 ± 8.2% for the collagen membrane. The barrier effect appeared to be similar in the IPN test group compared with the collagen membrane. In conclusion, this novel, easy-to-handle and apply, photochemically cross-linkable IPN hydrogel is an excellent non-animal alternative to porcine collagen membrane in guided bone regeneration procedures.
DNA Damage Response Alterations in Ovarian Cancer: From Molecular Mechanisms to Therapeutic Opportunities
Authors: Ovejero-Sánchez María , González-Sarmiento Rogelio , Herrero Ana Belén
Published: January 2023

The DNA damage response (DDR), a set of signaling pathways for DNA damage detection and repair, maintains genomic stability when cells are exposed to endogenous or exogenous DNA-damaging agents. Alterations in these pathways are strongly associated with cancer development, including ovarian cancer (OC), the most lethal gynecologic malignancy. In OC, failures in the DDR have been related not only to the onset but also to progression and chemoresistance. It is known that approximately half of the most frequent subtype, high-grade serous carcinoma (HGSC), exhibit defects in DNA double-strand break (DSB) repair by homologous recombination (HR), and current evidence indicates that probably all HGSCs harbor a defect in at least one DDR pathway. These defects are not restricted to HGSCs; mutations in ARID1A, which are present in 30% of endometrioid OCs and 50% of clear cell (CC) carcinomas, have also been found to confer deficiencies in DNA repair. Moreover, DDR alterations have been described in a variable percentage of the different OC subtypes. Here, we overview the main DNA repair pathways involved in the maintenance of genome stability and their deregulation in OC. We also recapitulate the preclinical and clinical data supporting the potential of targeting the DDR to fight the disease.
The Effect of Metalloestrogens on the Effectiveness of Aromatase Inhibitors in a Hormone-Dependent Breast Cancer Cell Model
Authors: Boszkiewicz Kamila , Moreira Helena , Sawicka Ewa , Szyjka Anna , Piwowar Agnieszka
Published: January 2023

Endocrine-disrupting compounds (EDC) play an important role in the increased incidence of breast cancer (BC). There are some 160 xenoestrogens that may be involved in the development of BC. Much less is known about the influence of xenoestrogens on the effectiveness of the treatment of BC. The aim of this study was to analyze the interaction of metalloestrogens (aluminum and chromium (III)) and drugs used in the treatment of hormone-dependent BC—aromatase inhibitors (AI)—letrozole and exemestane. A cell viability assay, a flow cytometer analysis of apoptosis and cell cycle phases, and protein activity of BAX and Bcl-2 were performed on two human breast cancer cell lines—MCF-7 and MCF-7/DOX. In MCF-7 cells, the lower concentration of exemestane and higher of letrozole, in combination with metalloestrogens, results in a decrease in the effectiveness of drugs. Additionally, in the MCF-7/DOX cell line, we observed that the combination of metalloestrogens and AI leads to a decrease in the drug’s effectiveness due to an increase in the viability of breast cancer cells (both concentrations of letrozole and higher concentration of exemestane). In both cell lines, the reduction in the effectiveness of AI, in combination with metalloestrogens, is not related to the influence on the cell cycle. Our results confirm that exposure to metalloestrogens may negatively affect the effectiveness of hormone therapy with AI. Further studies are needed to fully explain the mechanism of these interactions.
3q26.2/MECOM Rearrangements by Pericentric Inv(3): Diagnostic Challenges and Clinicopathologic Features
Authors: Tang Zhenya , Wang Wei , Yang Su , El Achi Hanadi , Fang Hong , Nahmod Karen Amelia , Toruner Gokce A. , Xu Jie , Thakral Beenu , Ayoub Edward , Issa Ghayas C. , Yin C. Cameron , You M. James , Miranda Roberto N. , Khoury Joseph D. , Medeiros L. Jeffrey , Tang Guilin
Published: January 2023

MECOM rearrangement (MECOM-R) resulting from 3q26.2 aberrations is often associated with myeloid neoplasms and inferior prognosis in affected patients. Uncommonly, certain 3q26.2/MECOM-R can be subtle/cryptic and consequently overlooked by karyotyping. We identified 17 acute myeloid leukemia (AML) patients (male/female: 13/4 with a median age of 67 years, range 42 to 85 years) with a pericentric inv(3) leading to MECOM-R, with breakpoints at 3p23 (n = 11), 3p25 (n = 3), 3p21 (n = 2) and 3p13 (n = 1) on 3p and 3q26.2 on 3q. These pericentric inv(3)s were overlooked by karyotyping initially in 16 of 17 cases and later detected by metaphase FISH analysis. Similar to the patients with classic/paracentric inv(3)(q21q26.2), patients with pericentric inv(3) exhibited frequent cytopenia, morphological dysplasia (especially megakaryocytes), −7/del(7q), frequent NRAS (n = 6), RUNX1 (n = 5) and FLT-3 (n = 4) mutations and dismal outcomes (median overall survival: 14 months). However, patients with pericentric inv(3) more frequently had AML with thrombocytopenia (n = 15, 88%), relative monocytosis in peripheral blood (n = 15, 88%), decreased megakaryocytes (n = 11, 65%), and lower SF3B1 mutation. We conclude that AML with pericentric inv(3) shares some similarities with AML associated with classic/paracentric inv(3)/GATA2::MECOM but also shows certain unique features. Pericentric inv(3)s are often subtle/cryptic by chromosomal analysis. A reflex FISH analysis for MECOM-R is recommended in myeloid neoplasms showing −7/del(7q).
Inhibition of PI3K Class IA Kinases Using GDC-0941 Overcomes Cytoprotection of Multiple Myeloma Cells in the Osteoclastic Bone Marrow Microenvironment Enhancing the Efficacy of Current Clinical Therapeutics
Authors: Kikuchi Hugh , Amofa Eunice , Mcenery Maeve , Schey Steve Arthur , Ramasamy Karthik , Farzaneh Farzin , Calle Yolanda
Published: January 2023

Osteoclasts contribute to bone marrow (BM)-mediated drug resistance in multiple myeloma (MM) by providing cytoprotective cues. Additionally, 80% of patients develop osteolytic lesions, which is a major cause of morbidity in MM. Although targeting osteoclast function is critical to improve MM therapies, pre-clinical studies rarely consider overcoming osteoclast-mediated cytoprotection within the selection criteria of drug candidates. We have performed a drug screening and identified PI3K as a key regulator of a signalling node associated with resistance to dexamethasone lenalidomide, pomalidomide, and bortezomib mediated by osteoclasts and BM fibroblastic stromal cells, which was blocked by the pan-PI3K Class IA inhibitor GDC-0941. Additionally, GDC-0941 repressed the maturation of osteoclasts derived from MM patients and disrupted the organisation of the F-actin cytoskeleton in sealing zones required for bone degradation, correlating with decreased bone resorption by osteoclasts. In vivo, GDC-0941 improved the efficacy of dexamethasone against MM in the syngeneic GFP-5T33/C57-Rawji mouse model. Taken together, our results indicate that GDC-0941 in combination with currently used therapeutic agents could effectively kill MM cells in the presence of the cytoprotective BM microenvironment while inhibiting bone resorption by osteoclasts. These data support investigating GDC-0941 in combination with currently used therapeutic drugs for MM patients with active bone disease.
Interventions for the Prevention of Oral Mucositis in Patients Receiving Cancer Treatment: Evidence from Randomised Controlled Trials
Authors: Colella Giuseppe , Boschetti Ciro Emiliano , Vitagliano Rita , Colella Chiara , Jiao Lebei , King-Smith Natalie , Li Chong , Nuoh Lau Yii , Lai Zacchaeus , Mohammed Ali Ibrahim , Cirillo Nicola
Published: January 2023

Oral mucositis is a common and most debilitating complication associated with cancer therapy. Despite the significant clinical and economic impact of this condition, there is little to offer to patients with oral mucositis, and the medications used in its management are generally only palliative. Given that mucositis is ultimately a predictable and, therefore, potentially preventable condition, in this study we appraised the scientific literature to evaluate effective methods of prevention that have been tested in randomised controlled trials (RCTs). Published high-level evidence shows that multiple preventative methods are potentially effective in the prevention of oral mucositis induced by radiotherapy, chemotherapy, or both. Anti-inflammatory medications (including benzydamine), growth factors and cytokines (including palifermin), cryotherapy, laser-and-light therapy, herbal medicines and supplements, and mucoprotective agents (including oral pilocarpine) showed some degree of efficacy in preventing/reducing the severity of mucositis with most anticancer treatments. Allopurinol was potentially effective in the prevention of radiotherapy-induced oral mucositis; antimicrobial mouthwash and erythropoietin mouthwash were associated with a lower risk of development of severe oral mucositis induced by chemotherapy. The results of our review may assist in highlighting the efficacy and testing the effectiveness of low-cost, safe preventative measures for oral mucositis in cancer patients.
The Impact of the COVID-19 Pandemic on the Number of Cancer Patients and Radiotherapy Procedures in the Warmia and Masuria Voivodeship
Authors: Kurowicki Marcin , Osowiecka Karolina , Szostakiewicz Barbara , Rucińska Monika , Nawrocki Sergiusz
Published: January 2023

(1) Background: It was suspected that the COVID-19 pandemic would negatively affect health care, including cancer treatment. The aim of the study was to assess the impact of the COVID-19 pandemic on the number of radiotherapy procedures and patients treated with radical and palliative radiotherapy in Poland. (2) Methods: The study was carried out in Warmia and Masuria voivodeship. The number of procedures and treated patients one year before and in the first year of the COVID-19 pandemic were compared. (3) Results: In the first year of the COVID-19 pandemic, the number of radiotherapy procedures and cancer patients treated with radiotherapy in Warmia and Masuria voivodeship in Poland was stable compared to the period before the pandemic. The COVID-19 pandemic has not affected the ratio of palliative to radical procedures. The percentage of ambulatory and hostel procedures significantly increased with the reduction of inpatient care in the first year of the COVID-19 pandemic. (4) Conclusion: No significant decrease in patients treated with radiotherapy during the first year of the pandemic in Warmia and Masuria voivodeship in Poland could indicate the rapid adaptation of radiotherapy centers to the pandemic situation. Future studies should be carried out to monitor the situation because the adverse effects of the pandemic may be delayed.
Contrasting Phylogeographic Patterns of Mitochondrial and Genome-Wide Variation in the Groundwater Amphipod Crangonyx islandicus That Survived the Ice Age in Iceland
Authors: Eme David , Westfall Kristen M. , Matthíasardóttir Brynja , Kristjánsson Bjarni Kristófer , Pálsson Snæbjörn
Published: January 2023

The analysis of phylogeographic patterns has often been based on mitochondrial DNA variation, but recent analyses dealing with nuclear DNA have in some instances revealed mito-nuclear discordances and complex evolutionary histories. These enigmatic scenarios, which may involve stochastic lineage sorting, ancestral hybridization, past dispersal and secondary contacts, are increasingly scrutinized with a new generation of genomic tools such as RADseq, which also poses additional analytical challenges. Here, we revisited the previously inconclusive phylogeographic history, showing the mito-nuclear discordance of an endemic groundwater amphipod from Iceland, Crangonyx islandicus, which is the only metazoan known to have survived the Pleistocene beneath the glaciers. Previous studies based on three DNA markers documented a mitochondrial scenario with the main divergence occurring between populations in northern Iceland and an ITS scenario with the main divergence between the south and north. We used double digest restriction-site-associated DNA sequencing (ddRADseq) to clarify this mito-nuclear discordance by applying several statistical methods while estimating the sensitivity to different analytical approaches (data-type, differentiation indices and base call uncertainty). A majority of nuclear markers and methods support the ITS divergence. Nevertheless, a more complex scenario emerges, possibly involving introgression led by male-biased dispersal among northern locations or mitochondrial capture, which may have been further strengthened by natural selection.
Assessing the Effect of Full Protection on the Biomass of Ericaria amentacea and Understory Assemblages: Evidence from Two Mediterranean Marine Protected Areas
Authors: Cannarozzi Laura , Bevilacqua Stanislao , Alongi Giuseppina , Asnaghi Valentina , Chiantore Mariachiara , Pagnotta Annachiara , Paoli Chiara , Rigo Ilaria , Vassallo Paolo , Falace Annalisa
Published: January 2023

Cystoseira sensu lato marine forests, which are among the most productive and diverse systems in rocky intertidal and subtidal habitats of the Mediterranean Sea, are experiencing a widespread decline throughout the basin due to increasing human pressures. Yet it is still unclear whether Marine Protected Areas (MPAs) may represent effective tools for conservation of these important habitat formers and their associated assemblages. Here, we compared the biomass of intertidal stands of Ericaria amentacea (C. Agardh) Molinari and Guiry and their understory assemblages between the no-take zone and control sites in two Mediterranean MPAs. We did not find evidence supporting a significant effect of full protection in increasing the biomass of E. amentacea stands and associated assemblages, except for macroalgae of the understory in one of the investigated MPAs, raising concerns on the potential effectiveness of MPAs in mitigating human impacts on these marine forests. Such findings call for major efforts to implement long-term monitoring programs of protected Cystoseira s.l. forests in order to inform an adaptive management of conservation measures within MPAs and eventually to set active interventions of restoration.
Variation in Dung Removal Rates by Dung Beetles (Coleoptera: Scarabaeoidea) in a Temperate, Dry Steppe Ecosystem
Authors: Jargalsaikhan Purevdorj , Altangerel Gombo , Enkhchimeg Tsedev , Aibek Ulykpan , Bayartogtokh Badamdorj
Published: January 2023

During their feeding process, dung beetles perform a series of ecosystem functions that provide valuable ecosystem services, such as soil fertilization, improvement of soil properties, plant growth enhancement, and biological pest control. However, in the grasslands of the Central Asian dry steppe, the effects of dung beetles on dung removal remain almost unstudied. Here, we examined dung removal by different dung beetle species (Colobterus erraticus (Linnaeus, 1758), Onthophagus bivertex Heyden, 1887, Onthophagus gibbulus (Pallas, 1781), Gymnopleurus mopsus (Pallas, 1781), Cheironitis eumenes Motschulsky, 1859, and Geotrupes koltzei Reitter, 1892), and compared the impacts with control treatments (without beetles) under natural pasture conditions and in the laboratory. We examined the influence of different variables on dung removal rates, such as dung type and dung beetle traits (nesting strategies, abundance, body size, and biomass). We found higher dung removal rates during the initial 48 h in field and laboratory conditions. Among nesting strategies, tunnellers demonstrated significantly higher dung removal rates than dweller and roller species. The highest amount of dung removal was estimated for C. eumenes (6.5 g/day by seven individuals). We found no significant relationship between dung removal rates and dung beetle body size or biomass, but we observed a strong negative correlation between dung beetle abundance and dung removal rates. Our findings highlight the importance of dung type and age, nesting strategies and abundances of dung beetles, and experimental conditions, which are the main factors driving the process of dung removal.
Economic Trading Susceptibility: Constructing Networks of Mutual Influence through the Fitness of Countries
Authors: Kumar Nishanth , Jensen Henrik Jeldtoft , Viegas Eduardo
Published: January 2023

The emergence of economic blocks and the level of influence countries exert on each other are fundamental features of the 21st century globally interconnected economy. However, limited quantitative research exists measuring the level of influence among countries and quantitatively determining economic blocks. This research develops a method to quantify the mutual influence of countries by making use of relatively standard procedures for complex networks in order to assemble non-trivial networks of influences and to identify symbiotic relationships. The methods are of significant help to an enhanced understanding of the global politics of trading and associations. Moreover, we develop the Mutual Influence Robustness (MIR) metric to work together with the Economic Fitness metric to provide some level of predictive modeling for the trends and future paths of countries. Our key results show the existence of a mutually influencing network around East and Southeast Asia, developed North America, and the northern and Iberian countries. Moreover, we find that it is possible to do some level of path predictability for the fitness and mutual influence of countries.
Pairing Optimization via Statistics: Algebraic Structure in Pairing Problems and Its Application to Performance Enhancement
Authors: Fujita Naoki , Röhm André , Mihana Takatomo , Horisaki Ryoichi , Li Aohan , Hasegawa Mikio , Naruse Makoto
Published: January 2023

Fully pairing all elements of a set while attempting to maximize the total benefit is a combinatorically difficult problem. Such pairing problems naturally appear in various situations in science, technology, economics, and other fields. In our previous study, we proposed an efficient method to infer the underlying compatibilities among the entities, under the constraint that only the total compatibility is observable. Furthermore, by transforming the pairing problem into a traveling salesman problem with a multi-layer architecture, a pairing optimization algorithm was successfully demonstrated to derive a high-total-compatibility pairing. However, there is substantial room for further performance enhancement by further exploiting the underlying mathematical properties. In this study, we prove the existence of algebraic structures in the pairing problem. We transform the initially estimated compatibility information into an equivalent form where the variance of the individual compatibilities is minimized. We then demonstrate that the total compatibility obtained when using the heuristic pairing algorithm on the transformed problem is significantly higher compared to the previous method. With this improved perspective on the pairing problem using fundamental mathematical properties, we can contribute to practical applications such as wireless communications beyond 5G, where efficient pairing is of critical importance. As the pairing problem is a special case of the maximum weighted matching problem, our findings may also have implications for other algorithms on fully connected graphs.
Simulating Fish Motion through a Diagonal Reversible Turbine
Authors: Koukouvinis Phoevos (Foivos) , Anagnostopoulos John
Published: January 2023

Utilization of unharnessed hydro-power necessitates designing fish-friendly hydraulic machinery. Towards this effort, the present work investigates various methods for tracking fish motion, ranging from particle tracking methods to accurate, but computationally expensive, body tracking methods, such as immersed boundaries and overset meshes. Moreover, a novel uncoupled 6-Degree of Freedom tracking technique is proposed, based on an approximated pressure field around the tracked body of interest, using steady-state flow field data, and including collision detection to walls. The proposed method shows promising results in terms of accuracy, being comparable to the more computationally expensive fully coupled methods at a tiny fraction of the execution time. The new method reveals location of fish–blade impact, as well as statistics of forces, pressure and flow shear that a passing fish is subjected to, both in the normal and reverse operation of the turbine. The low computational cost of the proposed method renders it attractive for optimization studies.
Study on the Lightning Protection Performance for a 110 kV Non-Shield-Wired Overhead Line with Anti-Thunder and Anti-Icing Composite Insulators
Authors: Hu Jianping , Zhu Ting , Hu Jianlin , Fang Zhen , Zhang Ruihe
Published: January 2023

Due to micro landforms and climate, the 110 kV transmission lines crossing the mountain areas are exposed to severe icing conditions for both their high voltage (HV) conductors and shield wires during the winter. Ice accumulation on the shield wire causes excessive sag, which leads to a reduced clearance between earth and HV wires, and could eventually result in tripping of the line due to phase-to-ground flashover. Due to the lack of effective de-icing techniques for the shield wires, removing them completely from the existing overhead line (OHL) structure becomes a reasonable solution to prevent icing accidents. Nevertheless, the risk of exposure to lightning strikes increased significantly after the shield wires were removed. In order to cope with this, the anti-thunder and anti-icing composite insulator (AACI) is installed on the OHLs. In this article, the 110 kV transmission line without shield wire is considered. The shielding failure after installation of the AACIs is studied using the lightning strike simulation models established in the ATP software. The lightning stroke flashover tests are carried out to examine the shielding failures on various designs for the AACIs. Assuming the tower’s earth resistance is 30 Ω, the LWL of back flashover and direct flashover are 630.88 kA and 261.33 kA, respectively, after the installation of AACIs on an unearthed OHL. Due to the unique mechanism of the AACI, the operational voltage level and the height of the pylon have a neglectable influence on its lightning withstand level (LWL). When the length of the parallel protective gap increases from 450 mm to 550 mm, the lightning trip-out rate decreases from 0.104 times/100 km·a to 0.014 times/100 km·a, and the drop rate reaches 86.5%. Therefore, increasing the gap distance for the AACI to provide additional clearance is proven to be an effective method to reduce the shielding failure rates for non-shield-wired OHLs.
Analysis and Forecasting of Monthly Electricity Demand Time Series Using Pattern-Based Statistical Methods
Authors: Pełka Paweł
Published: January 2023

This article provides a solution based on statistical methods (ARIMA, ETS, and Prophet) to predict monthly power demand, which approximates the relationship between historical and future demand patterns. The energy demand time series shows seasonal fluctuation cycles, long-term trends, instability, and random noise. In order to simplify the prediction issue, the monthly load time series is represented by an annual cycle pattern, which unifies the data and filters the trends. A simulation study performed on the monthly electricity load time series for 35 European countries confirmed the high accuracy of the proposed models.
Study on the Temporal and Spatial Evolution of China’s Carbon Dioxide Emissions and Its Emission Reduction Path
Authors: Shi Wei , Sha Zhiquan , Qiao Fuwei , Tang Wenwen , Luo Chuyu , Zheng Yali , Wang Chunli , Ge Jun
Published: January 2023

Based on the total carbon emission data of 30 provinces and cities in China from 2000 to 2020, this paper used non-parametric kernel density estimation and traditional and spatial Markov probability transfer matrix methods to explore the temporal and spatial dynamic evolution characteristics of carbon dioxide emissions in China and then used a super-SBM model to calculate the carbon emission reduction potential of each province. The results showed that: (1) from 2000 to 2020, the total carbon emissions in China showed an upward trend of fluctuation, from 1.35 Gt to 4.90 Gt year by year, with an annual growth rate of 13.10%. (2) The core density curve showed a double peak form of “main peak + right peak,” indicating that a polarization phenomenon occurred in the region. (3) The overall trend of carbon dioxide emissions shifting to superheavy carbon emissions was significant, and the probability of transition was as high as 74.69%, indicating that it was challenging to achieve leapfrog transition in the short term. (4) Based on the principle of fairness and efficiency of provincial carbon emission reduction, mainland China’s 30 provincial administrative regions can be divided into four types. Finally, the carbon emission reduction path is designed for each province.
Design of New Test System for Proton Exchange Membrane Fuel Cell
Authors: Xia Yuzhen , Lei Hangwei , Wu Xiaojun , Hu Guilin , Pan Hao , Fang Baizeng
Published: January 2023

A comprehensive test system for proton exchange membrane fuel cells (PEMFCs) is designed and developed for monitoring and controlling the inlet and outlet parameters and safety issues of fuel cells. The data acquisition and output instruction rely on the connection between PLC (programmable logic controller) and OPC (object linking and embedding for process control). Based on Siemens S7-200 series PLC and PID (proportion integration differentiation) technology, the margin of error in relative humidity of inlet air is controlled at less than 0.7%. Furthermore, a hydrogen recycling system and an alarm module are introduced, considering the hydrogen or nitrogen solenoid valve power failure, cooling fan power failure, temperature anomaly, and hydrogen leakage. This developed test system is evaluated by the experimental investigation of PEMFC performance. The results show that the test system has very good test and control performances. At a cell temperature of 40 °C, enhanced performance in the polarization tests is depicted at a high humidification temperature of 60 °C.
Lubricant Oil Consumption and Opportunities for Oil-Free Turbines in the Hydropower Sector: A European Assessment
Authors: Quaranta Emanuele
Published: January 2023

Lubricant oil is used in hydropower units to minimize friction, improving the turbine efficiency and reducing the wear. However, oil production is a pollutant process, while eventual spills may affect water quality and damage freshwater ecosystems. In this study, the lubricant oil consumption of the European hydropower fleet was estimated (considering its installed capacity of 254 GW). The energy required to extract and process the oil was also estimated based on available literature data. The oil consumption was estimated to be 22 × 103 tons/year, and the associated CO2 emissions are 105 tons/year. The lubricant oil costs EUR 116 million per year. Although this is only 0.0022% of the oil consumed as a primary energy source in the European context, and less than 0.4% of the European industry consumption of lubricant oil, results show that new bearing types and oil-free turbines (e.g., self-lubricating or water-lubricated turbines) can improve the sustainability of the hydropower sector, minimizing the risks and impacts associated with incidental oil spills and leakages. The provided data can also be used for Life Cycle Assessment analyses.
Green Building Technologies Targeting Carbon Neutrality
Authors: Cao Jingyu , Wu Wei , Hu Mingke , Wang Yunfeng
Published: January 2023

The construction industry is one of the three major worldwide energy consumers, producing nearly 30% of global carbon emissions [...]
Quantification of Root Systems and Soil Macropore Networks Association to Soil Saturated Hydraulic Conductivity in Forested Wetland Soils
Authors: Zhang Yinghu , Wang Lu , Zhang Wenqi , Zhang Zhenming , Zhang Mingxiang
Published: January 2023

Understanding the relationship between root systems, soil macropore networks, and soil hydraulic properties is important to better assess ecosystem health. In this study, treatments were performed in forested wetland soils with different vegetation densities, i.e., large (LWa) and small communities (LWb) of reed (Phragmites australis (Cav.) Trin. ex Steud.). At each plot, three undisturbed PVC cylinders (10 cm in diameter and 50 cm in height) were obtained, and X-ray microtomography (μCT) scanning was used to determine the root and macropore architectures. Results showed that the values of total root length and total root volume at LWa were significantly larger than those at LWb (p < 0.05). Imaged macroporosity, macropore volume, macropore length density, macropore node density, macropore branch density, mean macropore surface area, mean macropore diameter, and mean macropore volume at LWa were significantly larger than those at LWb (p < 0.05), whereas mean macropore length, mean macropore branch length, and mean macropore tortuosity at LWb were larger than those at LWa. Total root length and total root volume were positively correlated with soil saturated hydraulic conductivity. Imaged macroporosity, macropore volume, macropore length density, macropore node density, macropore branch density, mean macropore surface area, mean macropore diameter, and mean macropore volume were positively correlated with soil saturated hydraulic conductivity, whereas mean macropore length, mean macropore branch length, and mean macropore tortuosity were negatively correlated with soil saturated hydraulic conductivity. In conclusion, root systems and soil macropore networks constitute a complex synthesis inside soil environments, and together affect soil hydrological responses.
Prospects of GPU Tensor Core Correlation for the SMA and the ngEHT
Authors: Yu Wei , Romein John W. , Dursi L. Jonathan , Lu Ru-Sen , Pope Adrian , Callanan Gareth , Pesce Dominic W. , Blackburn Lindy , Merry Bruce , Srinivasan Ranjani , Kim Jongsoo , Weintroub Jonathan
Published: January 2023

Building on the base of the existing telescopes of the Event Horizon Telescope (EHT) and ALMA, the next-generation EHT (ngEHT) aspires to deploy ∼10 more stations. The ngEHT targets an angular resolution of ∼15 microarcseconds. This resolution is achieved using Very Long Baseline Interferometry (VLBI) at the shortest radio wavelengths ∼1 mm. The Submillimeter Array (SMA) is both a standalone radio interferometer and a station of the EHT and will conduct observations together with the new ngEHT stations. The future EHT + ngEHT array requires a dedicated correlator to process massive amounts of data. The current correlator-beamformer (CBF) of the SMA would also benefit from an upgrade, to expand the SMA’s bandwidth and also match the EHT + ngEHT observations. The two correlators share the same basic architecture, so that the development time can be reduced using common technology for both applications. This paper explores the prospects of using Tensor Core Graphics Processing Units (TC GPU) as the primary digital signal processing (DSP) engine. This paper describes the architecture, aspects of the detailed design, and approaches to performance optimization of a CBF using the “FX” approach. We describe some of the benefits and challenges of the TC GPU approach.
New Genetically Determined Markers of the Functional State of the Cardiovascular System
Authors: Kondakova Elena V. , Ilina Valeria M. , Ermakova Lyubov M. , Krivonosov Mikhail I. , Kuchin Kirill V. , Vedunova Maria V.
Published: January 2023

Nowadays, cardiovascular diseases (CVDs) occupy a leading position in population mortality. Since it is known that the development of cardiovascular pathologies is determined mainly by the human genetic burden, an urgent task of primary prevention of CVDs is to assess the contribution of gene polymorphism to the formation of cardiovascular risk. The material for the study was the blood of volunteers aged 21 to 102 years. Polymorphisms were determined by real–time PCR. Multichannel volumetric sphygmography was performed to analyze the functional state of the vascular wall. The study revealed that the rs5742904 polymorphism of the ApoB gene was found to be absent in the studied groups of long-livers and descendants of long-livers. Results indicated that the carriage of the heterozygous variant of the MMP9 polymorphism is associated with a favorable prognosis for cardiovascular system functioning. A tendency towards an increase in the rate of biological age acceleration among subgroups with AA and GG genotypes of the MMP9 gene and a negative value of biological age acceleration among heterozygous carriers of this polymorphism allele were found. The conducted studies make it possible to identify new associations of the studied polymorphisms with the functional state of the cardiovascular system, which is of great clinical importance and requires further study.