bluuebunny/crossref_metadata_2025 huggingface dataset:
Effect of perioperative sciatic nerve block on chronic pain in patients undergoing below-knee amputation: A randomised controlled trial
Authors: Makkar Jeetinder Kaur , Bandyopadhay Anjishnujit , Jain Kajal , Jafra Anudeep , Gopinathan Nirmal R. , Singh Preetmohinder
Published: October 2022

Background and Aims:

Many pain syndromes such as chronic phantom limb pain (PLP) and stump pain (SP), involving nociceptive and neuropathic pain, develop after amputation. Recent literature suggests that the use of regional blocks reduces repeated stimulation of transected nerve roots and thus prevents central sensitisation. This randomised, double-blind study was conducted to evaluate the effect of pre-emptive ultrasound-guided single-shot lateral sciatic nerve block on the occurrence of chronic pain at six months after traumatic below-knee amputation.

Methods:

Thirty patients undergoing traumatic lower limb amputation under general anaesthesia were randomised into two groups: Group B received sciatic nerve block pre-emptively using ultrasound with 20 ml of 0.75% ropivacaine, whereas group C received 20 ml of normal saline. Follow-up of patients was done till six months post-amputation. The primary objective was to assess the occurrence of chronic pain at six months. Pain at 15 days and one month after surgery, post-operative morphine consumption and post-operative nausea and vomiting (PONV) were the secondary outcomes assessed.

Results:

The occurrence of PLP at six months was comparable in the two groups, group B (46.7%) and C (66.7%). None of the patients developed SP at six months. Median intensities of phantom pain were 1.0 (range, 1–2.0) versus 1.0 (range, 1–2.0) (P = 0.36), and median intensities of SP 2 (range, 2–3.0) versus 3 (range, 2–3.0) (P = 0.39) at 1 month.

Conclusion:

Pre-emptive sciatic nerve block did not decrease the occurrence or severity of chronic pain after traumatic below-knee amputation.
Prevalence of Subclinical Vitamin K Deficiency in Early Infancy in Exclusively Breast-Fed Term Infants
Authors: Jain Gitanjali , Adhikari K. M. , Vasnik Gautam Kumar , Singh Daljit , Somasundaram Venkatesan , Gupta Rakesh , Dudeja Puja , Shaw Subhash Chandra
Published: October 2022

Background:

Late Vitamin K deficiency bleeding, is a disease of exclusively breast-fed infants attributable to poor content of Vitamin K in breast milk. We aimed to estimate the prevalence of subclinical Vitamin K deficiency, at 3 months of age in exclusively breast-fed term infants who were administered routine Vitamin K 1 mg intramuscular at birth.

Methods:

This prospective observational study was conducted between June 2018 and June 2020 in a Tertiary Care Teaching Hospital in Western India. Consecutive inborn infants, having received Injection Vitamin K at birth and on exclusive breast feeds attending immunization at 3 months of age were included. Half milliliter of venous blood was withdrawn for the estimation of Proteins Induced by Vitamin K Absence or Antagonist-II (PIVKA-II). Subclinical Vitamin K deficiency was defined as PIVKA-II level of more than 2 ng/mL.

Results:

The mean age of infants was 3.2 ± 0.2 months and the PIVKA II levels ranged from 0.19 to 10.07 ng/ml. Subclinical Vitamin K deficiency was present in 62 (32.63%) out of 190 infants.

Conclusion:

Significantly raised PIVKA II levels (>2 ng/mL) were detectable in 32.6% of infants after 3 months of age who had received 1 mg of Vitamin K at birth.
Impacts of intrathecal fentanyl on the incidence of postoperative nausea/vomiting: Systematic review and meta-analysis of randomized studies
Authors: Caballero-Lozada Andrés Fabricio , Gómez Juan Manuel , Torres-Mosquera Arley , González-Carvajal Álvaro , Marín-Prado Andrea , Zorrilla-Vaca Andrés , Zhao Xuechun , Li Jinlei
Published: October 2022

Post-operative nausea and vomiting (PONV) is an event of multifactorial origin with an incidence of 30% in the general population. Opioids such as fentanyl are being used as adjuvant to local anesthetic for its antiemetic effect. In this context, with this study we aimed to evaluate the impact of spinal fentanyl as an adjuvant on the incidence of PONV compared with a placebo, and shivering. A systematic search of randomized controlled trials that evaluated the use of spinal fentanyl in the prevention of PONV and shivering was conducted in different databases, of which 32 studies met the inclusion criteria. A total of 2116 patients scheduled for various surgeries, including cesarean section, orthopedic surgery in the lower limb, hysterectomy, and transurethral resection of the prostate, were included in the final analysis. The meta-analysis estimated the relative risk of incidence of PONV in the first 24 hours after surgery and secondary outcomes included the shivering symptom. The use of intrathecal fentanyl was associated with lower incidence of PONV, but not statistically significant when compared to the placebo (RR: 0.74 CI95%: 0.55-1.01 P = 0.06). Subgroup analysis showed a statistically significant reduction in PONV incidences with lower doses between 10 and 15 μg (RR: 0.44 CI95%: 0.35–0.55 P < 0.00001, I2 = 0%) but not with higher doses 20–25 μg. Secondary outcomes showed a decrease in incidence with the use of fentanyl vs the placebo (RR: 0.49, CI95% 0.33-0.72 P = 0.0003). Current evidence shows that the use of spinal fentanyl decreases the incidence of PONV, an effect favored using low doses.
Performance of prognostic scores in prediction of 30-day postoperative mortality in COVID-19 patients after emergency surgery: A retrospective cohort study
Authors: Karna ST , Gouroumourty R , Ahmad Z , Trivedi S , Thaware P , Singh P
Published: October 2022

Background:

Risk assessment with prognostic scoring, though important, is scarcely studied in emergency surgical patients with COVID-19 infection.

Methods and Material:

We conducted a retrospective cohort study on adult emergency surgical patients with COVID-19 infection in our institute from 1 May 2020 to 31 October 2021 to find the 30-day postoperative mortality and predictive accuracy of prognostic scores. We assessed the demographic data, prognostic risk scores (American Society of Anesthesiologists-Physical Classification (ASA-PS), Sequential Organ Failure Assessment (SOFA), Quick SOFA (qSOFA), Physiologic and Operative Severity Score for the enUmeration of Mortality and Morbidity (POSSUM) and Portsmouth-POSSUM (P-POSSUM) scores), surgical and anesthetic factors. We assessed the postoperative morbidity using the Clavien-Dindo scale and recorded the 30-day mortality. Correlation of prognostic scores and mortality was evaluated using Univariate Cox proportional hazards regression, receiver operating characteristic curve (ROC), Youden's index and Hosmer- Lemeshow goodness of fit model.

Results:

Emergency surgery was performed in 67 COVID-19 patients with postoperative complication and 30-day mortality rate of 33% and 19%, respectively. A positive qSOFA and ASAPS IIIE/IVE had a 9.03- and 12.7-times higher risk of mortality compared to a negative qSOFA and ASA-PS IE/IIE (P < 0.001), respectively. Every unit increase of SOFA, POSSUM and P-POSSUM scores was associated with a 50%, 18% and 17% higher risk of mortality, respectively. SOFA, POSSUM and P-POSSUM AUCROC curves showed good discrimination between survivors and non-survivors (AUC 0.8829, 0.85 and 0.86, respectively).

Conclusions:

SOFA score has a higher sensitivity to predict 30-day postoperative mortality as compared to POSSUM and P-POSSUM. However, in absence of a control group of non-COVID-19 patients, actual risk attributable to COVID-19 infection could not be determined.
Movie Recommender System using Machine Learning
Authors: Malik Sonika
Published: October 2022

In this research, we propose a movie recommender system that can recommend movies to both new and existing customers. It searches movie databases for all of the relevant data, such as popularity and beauty that is required for a recommendation. We apply both content-based and collaborative filtering and evaluate their advantages and disadvantages. To build a system that delivers more exact movie recommendations, we employ hybrid filtering, which is a combination of the outcomes of these two processes. The recommendation engines are also used for business purposes and to make strategies for organizations. Due to the growing demands of customers and user’s recommendation systems plays a huge role. These recommender systems also help us to utilize our time in the busy world by giving us more relevant searches. These systems are generally used with the movie’s websites or with many commercial applications and are of great use. This type of recommendation system can be also used for precise results. It will make movies suggestions more relevant as per the need of the users.
Deformations of Legendrian curves
Authors: Mendes Marco Silva , Neto Orlando
Published: October 2022

We construct versal and equimultiple versal deformations of the parametrization of a Legendrian curve.
Uniform regularity for the flow of a chemically reacting gaseous mixture
Authors: Sun Jianzhu , Tang Tong
Published: October 2022

Uniform regularity plays an important role in the global existence of strong solutions and large time behavior of global solutions. In this work, we prove the uniform regularity of smooth solutions to the compressible flow of a chemically reacting gaseous mixture in

\mathbb{T}^3

.
A Study on the Utilization of Cubic Unit Modelling: Mainly on the basis of producing & demonstrating FDP pilot product
Authors:   Korea Institute of Design Research Society, Ha Bong Soo
Published: October 2022

This paper examines development of Flexible Design Pattern pilot product & possibility of commercialization through demonstration. Above all, it concentrated on developing pilot product of ceramic, architectural materials for universal use & concrete for commercialization and grasped merit & demerit with product through demonstration. Above all, the process of developing pilot product is producing mold through selecting FDP unit type and modelling & 3D printing. In case of mold(output of PLA materials) which was to form clay for pottery that was attempted in the 1st place, it failed, because materials could not be detached from mold. Then, mold was changed and improved to silicon mold. In the subsequent forming process, the problem & know how for producing concrete FDP was acquired through 4 formings which used molds in 5 kinds. Afterwards, 18 sets of pilot products were completed by using mold in type (1-2), (2-3). Finally, listening to the merit & demerit of product through demonstration for which 3 professors related to design cooperated, pilot products were inevitably subject to sensory projection in the process of operating regular & irregular units. As a result, the complete works were satisfactory. More opinion was that once color is added, individual sensory projection would be further promoted, thereby making the products more satisfactory. After all, this opinion could be the representation of products attribute borne by FDP, the following interpretation is possible, namely, they may be competitive as decorative cubic tile & art kit products. Meanwhile, further opinion is that FDP has many technical tasks besides cubic shape or composition method and problems in use like cleaning or maintenance. Although technical part is excluded in this paper, technical part needs to be additionally examined including segmentation of shape design in order to complete products for sale or construction. This is to be studied in cooperation later.
A study on the improvement of UX / UI for communication between patients and the medical team
Authors:   Korea Institute of Design Research Society, Park Jun Hong
Published: October 2022

The purpose of this paper is to propose a conceptual model of the Pain Assessment system to improve communication between patients and the medical team, and to present a concrete way to realize it. To this end, among the representative pain assessment tools used in clinical practice, five methods of recording pain by the patient and three methods of describing the condition through observation by the medical team were identified and the contents were confirmed. Along with this, the definition and concept of the system and interface were confirmed, and the specific contents of the pain assessment system connected with the patients and the medical team were presented. After that, a hardware system, a pain assessment device based on wireless communication, was proposed to implement this in the field, and a software system that can track the pain assessment information reported for each patient was specifically configured.
Forecasting of the epidemiological situation: Case of COVID-19 in Morocco
Authors: Chouit El Mehdi , RACHDI Mohamed , BELLAFKIH Mostafa , RAOUYANE Brahim
Published: October 2022

Since the coronavirus pandemic started, many people have died due to the disease. The epidemic has been challenging to predict, as it progresses and spreads throughout the world. We used Auto-Regressive Integrated Moving Average (ARIMA) models to predict the outbreak of COVID-19 in the upcoming months in Morocco. In this work, we measured the effective reproduction number using the real data and the forecasted data produced by the two commonly used approaches, to reveal how effective the measures taken by the Moroccan government have been in controlling the COVID-19 outbreak. The prediction results for the next few months show a strong evolution in the number of confirmed and death cases in Morocco. We study the spread of COVID-19 in Morocco to see how many cases are discovered, recovered, and dead, and the forecasting of further cases is used as a basic novel method. It is based on time series models. We used coronavirus outbreak data from March 02, 2020, to August 04, 2021. ARIMA (Autoregressive integrated moving average) and Prophet time-series models are used to forecast the development of COVID-19, which is not a novel method. The mean absolute error, root mean square error, and coefficient of determination R2 were computed to assess the model's performance. Our study aims to provide a better understanding of the infectious disease outbreak that affected Morocco. It also provides information on the disease outbreak's epidemiology. Our study shows that the FBProphet model is more accurate in predicting the prevalence of COVID-19. It can help guide the government's efforts to prevent the virus' spread.
Bulanık Ters Mantık Yöntemi ve Çelik Boru Profiller ile Teşkil Edilmiş Çelik Kafes Sistem Elemanlarının Tasarımında Kullanımı
Authors: ÖZTEKİN Ertekin
Published: October 2022

Bu çalışmada, yapay zekâ yöntemlerinden biri olan bulanık mantık yöntemi kullanılarak, çelik boru profillerin çekme ve basınç kuvveti etkisindeki kapasitelerini belirleyebilmek için iki adet bulanık model oluşturulmuştur. 2018 Türk Çelik yapılar Yönetmeliğinde belirtilen GKT yöntemine göre oluşturulan her iki bulanık modelde de, çelik sınıfı S355 olarak sabit olarak tutulurken, kesit çapı (D), profil et kalınlığı (t) ve eleman uzunluğu (L) değişken parametreler olarak dikkate alınmıştır. Eksenel çekme kapasitesi (Tn) ve eksenel basınç kapasitesi (Pn) ayrı ayrı olarak bu modellerin çıktı parametrelerini oluşturmuşlardır. Her iki modelin oluşturulmasında aynı girdi değişkenleri değerlerine sahip ancak çıktı parametreleri farklı olan 1400 ‘er adet örnek çözüm kullanılmıştır. Kullanılan bu örnek çözümlerin haricinde 988 ‘şer adet farklı örnek çözüm ile bu modeller test edilerek, sırasıyla maksimum % 2.764 ve maksimum % 4.076 hata ile eksenel çekme ve basınç dayanımlarının tahminde kullanılabilecekleri ortaya konulmuştur. Daha sonra geliştirilen bulanık modellere, bulanık ters mantık yöntemi 3 farklı izostatik düzlem kafes sistem örneği için uygulanarak bu kafes sistemleri oluşturan çubuk elemanların tasarımları gerçekleştirildikten sonra dayanım kontrolleri karşılaştırmalı olarak 2018 Türk Çelik yapılar Yönetmeliğinde belirtilen GKT yöntemi ile gerçekleştirilmiştir. Sonuç olarak, bulanık mantık ve bulanık ters mantık yöntemlerinin birlikte aynı sayısal veriyi kullanarak boru kesitli çelik kafes sistem elemanların kapasitelerinin belirlenmesinde ve aynı zamanda tasarımlarının gerçekleştirilmesinde model hataları da dikkate alınarak güvenle kullanılabilecekleri ortaya konulmuştur.
Contemporary Terrorism as a Global Security Challenge and the Role of Criminal Law
Authors:   University of Belgrade, Faculty of Security Studies, Milosevic Mladen , Banovic Bozidar
Published: October 2022

For decades, terrorism has been an area of ​​significant interest of academics from different fields of research. However, until the end of the twentieth century, the terrorism wasn’t observed as a global threat. The terrorist attacks of the early 21st century in modern sociological and criminological literature are referred to as a milestone in the development of the phenomenon of terrorist crime. The post-modern or contemporary terrorism, by its essence, scale and phenomenology, significantly differs from classical and modern forms of this criminal phenomenon. The authors discuss conceptual definitions of terrorism and identify key elements for defining this phenomenon. The authors also indicate the specific characteristics of the contemporary (post-modern) terrorism, and then analyze the role of criminal legislation, focusing on the Serbian criminal legislation and the most important acts of international law in this area. The main question is whether the Serbian legal framework contains adequate legal instruments for fighting contemporary terrorism.
The Contemporary Penal Populism: the Global Trends and the Local Consequences
Authors:   University of Kragujevac, Faculty of Law, Sokovic Snezana
Published: October 2022

The penal populism as a special approach to shaping the social reaction to crime has a global character and has been present for a few decades already. The global social changes connected with the appearance and strenthening of the neoliberal socio-economic system, contributed to its appearance together with the role of the media, the changes of the appearing perception of the crime and the politization of crime. The basic characteristics refer to the establishment of new strategies of crime control, significant criminal-legal expansionism, more severe penal policy, the strengthening and expansion of the formal control, new penology. The most important consequence of the new criminal control practice is a great increase in the number of convicts with the prison penalty, which cannot be explained solely by the increase in crime. Since apart from the global character of the relevant social changes, the penal populism with its controversial consequences has not overtaken all the countries with the same intensity, a special attention is drawn by the countries which have kept the functional criminal-legal system out of the new punitiveness. The relevant research show that the level of punitiveness is in a significantly stronger correlation with economic policy, i.e. investments into the social policy, than with the real state of crime. The local reception of the global trends, both generally and in the criminal legislation system of Serbia, is characterized by inconsistence and neglect of the institutional and cultural incompatibility and the standardisation of thy hybrid law institutes which have a great difficulty of fitting into the national legal systems.
Globalization of the Plea Bargaining: Lessons From Countries With Unlimited System
Authors:   University of Kragujevac, Faculty of Law, Turanjanin Veljko
Published: October 2022

Plea bargaining is a global phenomenon among legal transplants of the criminal procedural law. It originated on the American continent, but become popular in the last 30 years around the world. Legislators, faced with the overloaded courts, found solutions in the comparative law that could solve this problem. Plea bargaining is far away from the perfect system of the solving criminal cases, since many critics follow this transplant. However, its positive sides are numerous, so it comes to life in every country where it is introduced. Of course, some states started from the beginning with rapid changes in legislations, completely turning its legal system to the Anglo-American. Others moved with significantly more caution, limiting plea bargaining on certain crimes. The author in this work deals with the agreement in countries with unlimited system of plea bargaining: Germany, Bosnia and Herzegovina and Serbia.
Some remarks on a very first form of protection of fiducia
Authors:   University of Kragujevac, Faculty of Law, Vladetic Srdjan
Published: October 2022

By concluding a fiducia, or by conditional transfer of ownership, the ancient Romans achieved different purposes (preservation of things, money loans etc.) and bypassing the legal formalism at the time. Initially, like many other institutes, fiducia was not protected by lawsuits, but the transferee (fiduciant) he achieved his protection through the institute of usureceptio fuduciae, as a special type of usucapio that Gaius analysed in his Institutes. This paper focuses on the reasons why the transferor had a right on protection by usureceptio fiduciae, possibilities of this protection in the cases of fiduciary agreement concluded with a friend and in the cases where this agreement is concluded with a creditor. Also, this paper is an attempt to answer the question: does the transferor commit the theft with taking over the transferred item?
NARODNI UNIVERZITET U LISTU „LESKOVAČKI GLASNIK“ (1924–1941)
Authors:   National Museum of Leskovac, Serbia, Petković Vladimir
Published: October 2022

The paper’s theme is related to the native history and the institution which marked the period between the two World Wars, and also is connected to the weekly newspaper known as „Leskovački glasnik“ that influenced the social conditions. The recordings of the activities organized by the National University are written in various newspaper articles in „Leskovački glasnik“ which became the great importance in cultural sense. The articles from „Leskovački glasnik“ are used as the primary source of information while writing this paper. The museum collection of Sergije Dimitrijević contains the majority of numbers of the newspaper “Leskovački glasnik”, from 1931 to 1941, with the exception of the year 1934.
DVA VAŽNA IZVORA O PROUČAVANjU ŽIVOTA I DELA MILIVOJA TRBIĆA (1913–1947)
Authors:   Institut za nacionalna istorija (Skopje, North Macedonia), Simonovski Aleksandar
Published: October 2022

History as an occurrence in the past can be researched if we have the appropriate historical sources available.Archives facilitate the work of historians by organizing and processing archival material. The historical research, almost without exception, begins with consulting and studying archival materials.In the State Archives of the Republic of North Macedonia in Skopje, there are two files relating to Milivoj Trbich, a member of the Ravna Gora Movement.The first file is the Trbich’s dossier, which was compiled by the State Security Service of the Socialist Republic of Macedonia. The dossier was a result of the successfully completed operation of the Administration of State Security to find and arrest Trbich on January 16, 1947. The dossier consists of 56 documents, 11 photographs and two materials with propaganda content of the Ravna Gora Movement in Macedonia. Most of the documents were prepared by the Administration of State Security of the People’s Republic of Macedonia.The second file is the dossier that was created as a result of the conducted court trial against Trbich and against five other persons from June 11 to June 13, 1947. The court trial was held in the District Court in Skopje. This dossier contains 119 documents. The majority of the documents have a judicial content.The two dossiers represent two important sources for the study of the life and work of Trbich.
ŠTAMPANA GLASILA JNP ZBOR O POLITIČKOBEZBEDNOSNOJ SITUACIJI U BANOVINI HRVATSKOJ (1939–1940)
Authors:   Institute of History Belgrade, Dragosavljević Vasilije
Published: October 2022

In this paper, I shall analyse a number of articles published by the Yugoslav People’s Movement Zbor (JNP Zbor) in its party papers and newssheets, with the aim of reconstructing the attitude adopted by this political organization regarding the political and security situation in the Banate of Croatia in the period 1939-1940. In particular, the focus shall be on the process of the downfall of the regime established by the Croatian Peasant Party in the Banate of Croatia, which resulted from the persecution of Serbs and other non-Croat population and concurrent conflicts within the Croatian national movement. Special attention shall also be paid to the repressive measures taken by the Croatian Peasant Party regime against the Serbian population, whose sufferings were a prelude to the genocide that the Ustashe regime eventually perpetrated against the Serbs in the Independent State of Croatia (NDH) during the World War 2.
SRPSKA POLITIČKA EMIGRACIJA I JUGOSLOVENSKO– AMERIČKI ODNOSI 1970-IH GODINA
Authors:   University of Belgrade, Faculty of Political Sciences, Mišić Saša , Marjanović Boban
Published: October 2022

The paper analyzes the role that Serbian political emigration in the United States of America had in Yugoslav-American relations during the 1970s. The action of Serbian political emigration against Socialist Yugoslavia was a chronic problem in the relations between the two countries. In the first half of this decade, during the terms of Presidents Nixon and Ford, the U.S. didn’t show understanding for the Yugoslav demands to prevent the acting of this emigration on American soil. With the arrival of the Carter administration in the second half of the 70s, the attitude towards this problem changed. In order to further improve cooperation with Yugoslavia, the U.S.A. approached solving this complex issue with more determination. The result of scientific research in this paper shows that at the end of the 1970s, there was a change in the policy of the American administration towards Serbian political emigration in America.
POLITIČKO NASILjE I UKIDANjE USTAVNIH PRAVA REPUBLIKE SRPSKE: ODUZIMANjE TERITORIJE, VOJSKE I PRAVOSUĐA, 1996–2006.
Authors:   Institute for Balkan Studies, SASA, Vukadinović Igor
Published: October 2022

The study examines the techniques of political violence used by the Bosniak political elite and Western countries led by the United States, Germany, and the United Kingdom in order to disempower the Republika Srpska and, in the long run, abolish it. The land, army, and judicial system were targeted as crucial parts of the Republika Srpska’s statehood, as confirmed in the 1995 Dayton Peace Agreement. All seizures of Srpska’s competencies were carried out in violation of the peace agreement and the Constitution of Bosnia and Herzegovina, as well as basic international law norms and egregious abuses of democratic procedures. Western countries have treated Bosnia and Herzegovina as a lawless zone, subordinating its democratically elected bodies and institutions to their own will, embodied in the form of “High Representative” or “Supervisor” in the Brcko Municipality. The state of lawlessness and the principle of the “right of the stronger,” according to which the High Representative had the authority to pass and repeal laws, remove democratically elected officials, and prohibit different people from engaging in politics, provided a framework within which elements of the Republika Srpska’s statehood could be abolished against its citizens’ will
NOVOBOŠNjAŠTVO ALIJE IZETBEGOVIĆA KAO IDENTITETSKI KONSTRUKT SINTETIČKE NACIJE I BEZBEDNOSNI RIZICI PO REPUBLIKU SRPSKU
Authors:   Institute for Political Studies, Belgrade, Despotović Ljubiša , Glišin Vanja
Published: October 2022

In the paper, the authors deal with the issue of identity and nations in the post-Yugoslav area, since from the 19th century until today there have been many disagreements and ambiguities on this issue, which should be clarified. The basic question concerns the origin and development of nations in this area, that is, the construction of synthetic identities and nations as agreed nations. Therefore, in the first part, the authors provide an overview of scientific knowledge concerning nations and identities and derive a theoretical model of synthetic nations, as an attempt to comprehensively respond to a complex phenomenon. In the second part of the paper, based on previous scientific knowledge, the authors analyze the process of the creation of the Bosniak nation and its development from the 19th to the end of the 20th century, when it was internationally recognized. Finally, aware of the facts about the process of the creation of the Bosniak nation, that is, the new Bosniakism of Alija Izetbegović, the authors derive security risks for the Republic of Srpska.
MIT O „VELIKOJ SRBIJI“ U NARATIVIMA NEMAČKE PROPAGANDE
Authors:   University of Belgrade, Faculty of Political Sciences, Radojković Miroljub , Jevtović Zoran ,   University of Niš, Faculty of Philosophy
Published: October 2022

Considering the continuity of anti-Serbian propaganda of German politics, the authors single out the ambiguity and tendency with which ideas about the guilt and responsibility of only one party should have been implanted in the consciousness of the German people. Comparing the dominant narratives from the period that preceded the great world wars, but also the conflicts in the former Yugoslavia during the nineties of the last century, they point to the ethnic contempt and ideological labeling by which the Serbian side was stigmatized for decades, with no chance to hear its side of the truth. The framing of propaganda matrixes served the purpose of obtaining legitimacy for the political actions that followed, and under the guise of crushing “Greater Serbian hegemony” Serbia was repeatedly bombed, with open attempts to subjugate it militarily and economically. Ideas about the “solution” of the Serbian question and the “supplementary economic space” have been woven into the geopolitical program of the German elite since the Berlin Congress, but only in the current reality do they openly indicate the strategic goals of expanding the military presence and the dominance of economic interests.
Tefsir İlminin Bilinmeyen Siması Molla Huveyş; Hayatı ve Beyânu’l-Me‘ânî Adlı Tefsiri
Authors: EFE Seyfullah , AYDEMİR Mehmet
Published: October 2022

Kur’ân-ı Kerim’in anlaşılması için geçmişten günümüze çokça gayret sarf edilmiştir. Makalemizin konusu olan Molla Huveyş ve tefsiri de bu zincirin bir halkasıdır. 1880-1978 yılları arasında yaşamış, hem Suriye’de hem de Irak’ın kuzey bölgelerinde hâkimlik/kâdılık görevlerinde bulunmuştur. Yazar, 1936-1939 yılları arasında “Beyânu’l-me‘ânî ‘alâ hasebi tertibi’n-nüzûl” adıyla ilk kez surelerin nüzûl sıralamasına göre tefsirini kaleme almış ve eser 1962 yılında sadece bir kez basılmıştır. Altı ciltten oluşan tefsirin ilk dört cildi Mekkî sûreleri içerirken son iki cildi Medenî sûreleri barındırmaktadır. Kendi alanında ilk sayılan ve Türkiye’de de tanınmayan bu müfessirin tanıtımı ve tefsir metodunu açığa çıkarmak için bu makaleyi kaleme aldık. Makale üç ana başlıktan oluşmaktadır. İlk başlıkta müellifin hayatı, eserleri ve tefsirinin genel özellikleri incelenmiştir. İkinci bölümde eser, rivâyet ve dirâyet tefsir yöntemi açısından ele alınmıştır. Üçüncü bölümde ise Kur’ân tarihi, sebeb-i nüzul, Mekkî-Medenî, nesh, tekrar, garîbu’l-Kur’ân ve fezâilu’l-Kur’ân gibi tefsirinde yer verdiği Kur’ân ilimleri irdelenmiştir.
The Sacred Space of Mangystau: the Content of Unusual Epitaphs
Authors:   Gumilyov Eurasian National University, Shokhayev M.T. , Nurdauletova B.I. ,   Sh. Yesenov Caspian University of Technology and Engineering
Published: October 2022

The article presents a meaningful division of translations of unusual epitaphs found in the Shakpak ata rock mosque, Sisem ata pantheon, Karaman ata necropolis during expeditions to the sacred places of Mangystau. The translation of the records in the found stone was compared with the published results of the previous study and translation, and some adjustments were made. The epitaphs provided examples of the fact that the question raised and the reflections in it are linked to the work of local poets and zhyrau, have a common worldview, and border within the Sufi current of Islam. During the research proposals were formulated to turn some elementary concepts into a scientific problem, considering them from a different angle. Special attention was paid to the specifics of the religious context concerning the uniqueness of epitaphs, which are considered the main requirement to become an object of literary studies. When considering the epitaph of the peoples of the East, especially the peoples of Islam, importance was attached to the importance of a fundamental approach to the principles of religion. The semantic analysis of the accumulated epitaphs was carried out with an emphasis on keywords, the purpose of writing the found epitaphs was predicted and a reference was made to the religious basis of the national worldview in a space that has not lost its sacredness both in antiquity and at the present time.
Formation of Innovative STEM-education
Authors:   Khoja Akhmet Yassawi International Kazakh-Turkish University, Kazbekova G.N. , Ismagulova Zh.S. ,   Khoja Akhmet Yassawi International Kazakh-Turkish University
Published: October 2022

The article is devoted to the topical issue of forming a new direction of innovative STEM education. The purpose of the study is to analyze the essence and content of STEM education, identify the main problems and contradictions, and identify the main approaches to its development. To solve the tasks set, a set of theoretical methods corresponding to the subject of research and the goal was used. The theoretical and methodological basis of the study was system competencies and personal and activity approaches. A number of important problems and contradictions in the implementation of STEM education are identified, for example, the traditional education system does not fully meet the requirements and requirements of training and training of the workforce of the XXI century; difficulties in teaching subjects using the STEM method; low level of academic performance in subjects of physical and mathematical profile, as well as lack of ability to solve specific subjects. The article emphasizes the complexity and versatility of STEM education, as a result of which a wide variety of programs are being developed by type, direction and level of complexity to solve problems related to the lack of STEM literacy. A brief description of the main approaches to the development of these programs was given, and the main factors of reforming education in the STEM direction were identified. All the leading countries of the world were noted.
PROFESSIONAL-ORIENTED ENGLISH LANGUAGE TEACHING TO THE SECOND-YEAR STUDENTS OF INFORMATION SYSTEM SPECIALITY
Authors:   Kazakh Ablai Khan University of International Relations and World Languages, KALDAROVA A.K.
Published: October 2022

This article describes the current state of the formation of foreign language professional-communicative competence of IT students at International Information Technology University (IITU) and teaching English for professional purposes (EPP) using Information and Communication Technologies (ICT). This work outlines the purpose of teaching English language as the development of students' communicative skills, which means the development of practical knowledge of English language. The analysis of EPP teaching methods related to its usage in oral and written communication, both in the process of future professional activity and for further self-education is given in this work as well. It is proved that the main advantage of using ICT in teaching professional oriented English is the shift of emphasis from traditional verbal ways of transmitting information to audiovisual methods. The article offers a set of exercises using digital educational resources in teaching professional oriented English course. An experiment which was carried out with twenty-seven students who were studying offline is presented in the work. There were two STEM (Science, Technology, Engineering and Math) groups who were studying professional oriented English language course in this study. According to the academic calendar of the course, they had EPP classes three hours a week and they had to complete some activities using educational tech tools, such as Padlet, Microsoft Teams, Socrative, blogs, etc. After completing the tasks, an online survey was conducted, and students had to leave their feedback on the usage of tech tools while learning professional oriented English language. This article also provides an overview of student performance in a continuous rating without midterm exams. The analysis of the study results confirms the correctness of the chosen methodology to achieve the objectives of the curriculum, and the usage of practical methods in teaching EPP make learning at the university didactically effective and valuable.
Historical Aspects of the Colonial Education System in the South Kazakhstan Region
Authors:   Khoja Akhmet Yassawi International Kazakh-Turkish University, Hakan A.S. , Rsymbetova L. ,   M. Auezov South-Kazakhstan University, Khazretalikyzy R. ,   Khoja Akhmet Yassawi International Kazakh-Turkish University
Published: October 2022

The article is devoted to a factual analysis of the history of the activities of the colonial authorities in reforming the education system in the Turkestan region. After the completion of the occupation in the region, the colonial authorities faced such problems as strengthening the border; creating conditions for Russian settlers; a sharp increase in cotton production; establishing the political stability of the local Muslim population; reforming the education system. Among these problems, the article presents a historiographical and factual analysis of attempts to form the colonial education system. The education policy of the authorities, which served the imperial interests, was to displace the traditional education system in the region. It was suggested that traditional educational institutions were excluded from government support due to the fact that the authorities adhered to the principle of «neglect» in relation to Islam and religious schools. The modernized forms of education in the region of Russian-foreign schools have replaced the traditional ones. An analysis of the experience of reform changes implemented by the educational policy of the colonial authorities showed that the modernization of the education system was subordinated to the imperial interest. It was concluded that the educational activity of the jadit movement formed in the region was presented as an alternative to the colonial educational reforms. In addition, data on the impact of Jadid ideas on educational activities in the south of Kazakhstan were analyzed.
Great Silk Road and Kazakhstan
Authors:   The School of History, Northwest University, Zangadiluly N.
Published: October 2022

The author thinks that his short research article on the Great Silk Road has a lot of content, a long period of research, a wide range of research sources and a number of unique features that make it interesting for those who are interested in this field. Today, the study and further development of the Great Silk Road, which attaches great importance to the study of ancient civilizations, is a matter of incalculable importance and significance. From the first appearance of silk to its production and transformation into a valuable commodity, which served as the basis for the name of the great medieval strategic road, the Great Silk Road, is narrated by ancient Chinese sources. At the same time, this article describes the important historical role of ancient Kazakhstan in the formation and development of the Great Silk Road as a medieval strategic road. The original and key parts of the historical path, which marked the beginning of the trade named after silk, have flourished in the Kazakh steppe from time immemorial. The fact that the Kazakh land was not only the territory through which the Silk Road passed, but also played a historical role in turning this simple way of giving into a way of exchanging civilization between the West and the East, is confirmed by Chinese handwritten sources. Moreover, according to the information provided by modern significant Chinese information sources, the connection of the Nurly Zhol program proposed by the ex-President of the Republic of Kazakhstan with the One Belt, One Way program is revealed. It is proved that independent Kazakhstan plays an important role in the modern reconstruction of the historical path. Thus, both the past and the present of the Great Silk Road are inextricably linked with Kazakhstan.
Study on Control of Blood Sugar with Different Types of Insulin in A Tertiary Care Hospital
Authors: Raouf Khwaja Amtul , Koneru Dr. Anupama , Chandrasekhar Dr. C N , Samreen Neha , Ahmed Qansaa , Muskaan Afreen
Published: October 2022

The main aim of study is to check optimum control of blood sugar using Human actrapid insulin and Human mixtard insulin in a range of 100-200mg/dl at tertiary care hospital. 114 patients with Type 2 Diabetes mellitus were treated with different insulin’s. The data collected is Baseline comparison of HbA1c% of two different insulin’s, Random blood sugar values at different time intervals (7AM, 1PM, 7PM) and post prandial blood sugar values were recorded to show the effective insulin among them. Oral hypoglycemic drugs were also administered to few patients. The baseline comparison of HbA1c% does not showed a significant difference at p value 0.8054. The baseline values of HbA1c% were compared with patients received HAI at p value <0.0001 showed significant reduction after treatment. Likewise baseline values of HbA1c % were compared with patients received HMI at p value <0.0001 showed reduction after treatment. The GRBS in patients received HAI at different time intervals did not show a significant difference at p value 0.1506. The GRBS in patients received HMI at different time intervals was found to be significant reduction at p value 0.0038. The follow-up data of GRBS after 3 months was also studied and showed a significant reduction of sugar levels in patients received HAI (P value0.0059) and in patients received HMI (P value -0.0028). The PPBS comparison between HMI and HAI did not show a significant difference at p value-0.1220. Human mixtard insulin showed significant effectiveness compared to Human actrapid insulin at confidence interval of 95%, hence p value of <0.05 is considered significant.
A Comparative Study of Effectiveness of Two Intensive Statin Regimen in the Treatment of Coronary Artery Disease in A Tertiary Care Hospital
Authors: Raouf Khwaja Amtul , Ahmed Sofia , Gaikwad Supriya , Asra Syeda
Published: October 2022

The study's goal is to compare and evaluate Rosuvastatin and Atorvastatin's efficacy and the numerous variables that affect the progression of coronary artery disease. Statin prescription recommendations for people with coronary artery disease (CAD) and their safety and effectiveness in people with high cholesterol levels are included. For the 100 patients who received statins for coronary artery disease, we calculated the results using SPSS Software, which includes the Mean technique, standard deviation method, t-test, and chi-square test. The percentage of men in group I was 87 per cent, while the percentage in group II was 80%. Groups I and II, on the other hand, had female populations of 13 and 20%, respectively. The baseline comparison of lipid profiles showed a significant difference between the two groups. The baseline values of total cholesterol were compared, and a significant difference was found statistically in patients treated with Rosuvastatin at a p-value <0.0001. Likewise, baseline values of HDL-CH were compared, and a significant difference was found statistically in patients treated with Rosuvastatin at P value <0.0001 in group I and 0.0003 in group II. The baseline values of LDL-CH were compared, and a significant difference was found statistically in patients treated with Rosuvastatin at P value 0.0271 in group I and 0.0101 in group II. The baseline values of Triglycerides were compared, and a significant difference was found statistically in patients treated with Rosuvastatin at P value 0.0104 in group I and 0.0184 in group II. Results illustrate that Rosuvastatin is safer and more effective in lowering LDL-CH levels than Atorvastatin. Management and lowering serum cholesterol levels is the main objective in attempting to prevent or treat atherosclerotic cardiovascular events. We considered Percentage changes in lipid parameters and rates of LDL-CH goal attainment in patients with coronary artery diseases. Rosuvastatin was found to be more effective than Atorvastatin at a confidence interval of 95%. Hence P-value <0.05 is considered significant.
Evaluation of Pharmacological Potentialities of Polar and Nonpolar Fractions of Justicia aurea Extract
Authors: Uddin A. N. M. Shofi , Bokshi Bishwajit , Ahmed Md Iqbal , Karmakar Utpal Kumar , Biswas Nripendra Nath , Sadhu Samir Kumar
Published: October 2022

This study aims to explore analgesic, antidiarrheal, neuropharmacological, and antibacterial activities of petroleum ether and water fractions of Justicia aurea (J. aurea). The results of analgesic activity showed that both nonpolar (petroleum ether) and polar (water) fractions of J. aurea extract at 250 and 500 mg/kg significantly suppressed the writhing reflex dose-dependently. Here, the potentiality of petroleum ether fraction was higher than that of water fraction. In the castor oil-induced diarrheal mice, both fractions of J. aurea extract, at 250 and 500 mg/kg, significantly delayed the onset of diarrhea and lessened the total number of feces in a dose-dependent manner. Of the two fractions, the nonpolar fraction was found to exhibit a better effect. Both fractions appreciably reduced the number of squares crossed by the mice at both 250 and 500 mg/kg. At 500 mg/kg, petroleum ether fraction reflected a slightly better effect than that of water fraction. In disc diffusion antibacterial assay, both fractions showed minor effects against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus), however, only the water fraction exhibited low activity against Salmonella enterica (S. enterica). In conclusion, the nonpolar fraction of J. aurea. showed better analgesic, antidiarrheal, and CNS depression effects.
Future and Current Scenario of Role Pharmacovigilance for Pharmacist in India
Authors: Chouhan Ashwin Singh , Purohit Nehal , Soni Nayan , Parihar Bharat , Prajapat Ram Prasad , Rawal Lakshey , Chandel Mahendra Nath
Published: October 2022

Pharmacovigilance is science and activities relating to the detection, assessment, understanding and prevention of adverse effects or any other drug-related problem. We conducted this research paper by observing the different types of reviews, as well as conducting and evaluating literature review papers. Pharmacovigilance is worried about just two results: security and viability. It addresses pretty much every part of the medication lifecycle from preclinical improvement to post-market reconnaissance. Pharmacovigilance is the science and movement associated with collection, detection, assessment, monitoring, and counteractive action of untoward impacts with pharmaceutical items.