bluuebunny/crossref_metadata_2025 huggingface dataset:
ROLES OF FOREIGN LANGUAGE LEARNERS AND TEACHERS IN CONTEXT OF DIGITALIZATION AND ONLINE INTERCULTURAL EXCHANGE
Authors: Matović Ivana
Published: March 2022

Even though there have been discrepancies when it comes to the importance of intercultural competence development in foreign language learning, with the emergence of new generations of young technocrats growing up in the world of rapid globalization, it is becoming clear that intercultural awareness in this process cannot be disregarded, and the language itself out of its context cannot be fully comprehended. The aim of this piece of writing is to point to the fact that digital technologies in language classroom are therefore of paramount importance, since they enable us to overcome physical distances among cultures and stimulate the development of skills needed for every global citizen. The intention goes beyond this in a way that it shows how the enabled online intercultural communication affects the roles of language learners and teachers and move students to central position in foreign language learning. Furthermore, it underlines the need for teacher support in the development of all the necessary competences which would finally lead to promoting and fostering learner autonomy. It also observes that OIE cannot alone promote language and skill competence development, and calls for blended approach which comprises both online and offline sessions that allow for reflection crucial for foreign language acquisition.
EXAMPLES OF MATHEMATICAL PROBLEMS IN PRIMARY AND SECONDARY EDUCATION THAT INCLUDE THE ACTUAL CALENDAR YEAR
Authors: Simjanović Dušan , Randjelović Branislav , Vesić Nenad , Penjišević Aleksandra
Published: March 2022

It is widely believed that math classes in primary school belong into the category of least favorite classes. Entire teams of psychologists, educators and mathematicians have studied the student aversion (and, to a certain extent, parent antipathy) to math classes, but they have also studied methods and ways to overcome this problem. They have tried to find a way to improve students’ activities, to make them more engaged in classes, and to increase their motivation. One of the opinions is that the student success requires their strong will, persistence, diligence and perseverance. Certainly, the competence, motivation and consistency of teachers, wholead them to the world of knowledge, have a great influence. One of the methods of achieving a positive influence of teachers, in the domain of increasing interest in mathematics and reducing aversion to it, is the use of interesting mathematical problems, in which the numerical value of the current calendar year or even the current date appears. The aim of this paper is to point out how the motivation of primary school students to adopt mathematical content can be increased. With concrete examples of interesting algebra problems, which tickle students’ fancy and make them think, we show how some lessons can be learned.
METHODOLOGICAL APPROACH TO CONGRUENCE OF QUADRILATERALS IN HYPERBOLIC GEOMETRY
Authors: Zlatanovic Milan , Aguilar Victor
Published: March 2022

In this paper we will prove new criteria for the congruence of convex quadrilaterals in Hyperbolic geometry and consequently, display the appropriate methodological approach in teaching the same. There are seven criteria for the congruence of hyperbolic quadrilaterals, while there are five for the congruence of Euclidean quadrilaterals. Using a comparative geometric analysis of quadrilateral congruence criteria in Euclidean and Hyperbolic geometry we described all possible cases and made a methodological approach to the problem. The obtained results can influence the approaches to the study of these contents with students in the hyperbolic geometry teaching.
DIGITAL TOOLS IN MUSEUM LEARNING – A LITERATURE REVIEW FROM 2000 TO 2020
Authors: Pavlović Dragana
Published: March 2022

This paper discusses the relationship between new technologies and learning in museums, as a significant issue that is increasingly occupying the attention of many researchers, especially in developed countries. The connection between digital technologies and modernization of the learning process in museums is pointed out, which is more and more present, and is becoming an integral part of formal education. Museums, as institutions for the preservation of tradition and culture, are increasingly using digital media in their practice, as intermediaries in the development of a system of culture and tradition knowledge among the younger generations. The aim of this paper is to provide a chronological overview of new technologies used for learning in museums, based on the review and analysis of selected literature. For the purposes of this paper, all research studies are classified into four time frames in which the application of digital technologies in learning in museums can be monitored, from the first used tools to the appearance of virtual museums. The results of the research show that there is a connection between the development of new digital technologies and learning in museums, ie that the learning process in museums is modernized and changed in accordance with the development of modern digital tools. The paper concludes that today, learning in museums goes beyond existing traditional models, based on visits, lending of exhibits and lessons in museums and is increasingly becoming a modern learning process based on digital technologies.
EFFECTS OF THE ACROBATIC PROGRAM ON THE BODY COMPOSITION AND FLEXIBILITY OF ADOLESCENTS
Authors: Miletić Marija , Aksović Nikola , Bjelica Bojan , Veličković Saša , Ilić Hadži Saša
Published: March 2022

The aim of the research was to determine the effects of acrobatics programs (ground floor and skipping) on the body composition and flexibility of adolescents. The sample consisted of 50 male adolescents, seventh grade students of the elementary school "Bubanjski Heroji" in Niš, aged 14 years ± 6 months. The experimental group (n = 25) conducted 2 x 45 min per week experimental acrobatics program (ground floor and skipping) The control group (n = 25) continued with the program of regular physical education classes (handball and volleyball) 2 x 45 min per week. The results of the study showed positive changes in body composition: BMI, %MAT, %MIT and flexibility: PLNL, RANL, ISKP caused by the acrobatics program. Based on these results, it can be concluded that the experimental program of acrobatics lasting 16 weeks is an effective method that leads to a statistically significant improvement in body composition and flexibility of adolescents.
Special Dio 3-Tuples Involving Square Pyramidal Numbers
Authors: Saranya Dr. C. , Achya B.
Published: March 2022

Abstract: In this communication, we accomplish special dio 3-tuples comprising of square pyramidal numbers such that the product of any two members of the set subtracted by their sum and increased by a polynomial with integer coefficients is a perfect square. Keywords: Special dio 3-tuples, Pyramidal number, perfect square, square pyramidal number.
Do e-services and promotion affect customer loyalty?
Authors: Meitiana Meitiana , Tuwuh Sembhodo Abimanyu
Published: March 2022

This study aims to determine the effect of the quality of electronic services and sales promotion on customer satisfaction and loyalty, either directly or indirectly, where customer satisfaction is an intervening variable. This research is explanatory research with 96 respondents. Determination of the sample using non-probability sampling technique and applying structural equation modeling for analysis. The results of the study show that the quality of electronic services has a positive and significant effect on customer satisfaction; electronic services have no significant impact on loyalty; sales promotion has a positive and significant impact on customer satisfaction; sales promotion has a negative and significant effect on customer loyalty; customer satisfaction has a positive and significant impact on customer loyalty; the quality of electronic services has a positive and significant impact on customer loyalty through customer satisfaction. Sales promotion has a positive and significant effect on customer loyalty through customer satisfaction.
Factor Analysis of investment intention: Millennials and Gen Z perspective
Authors: Suryani Wan , Tobing Fitriani , Emelia Girsang Yesika
Published: March 2022

This study aims to determine what factors influence the investment interest of millennials (Y) and Z generations in North Sumatra. This research was conducted by survey method, and the number of respondents in this study was 280. The results indicate that two main factors determine millennials and generation z in investing intention: first, knowledge, self-motivation, social environment that has investment experience, and initial capital; and second, variables include information, transparency, social media influencers, and financial literacy.
Performance of Indonesian manufacturing companies: Economic value-added approach
Authors: Tjandra Betty , Sulistyorini Dwi , Mulia Rizky , Anggraeni Titi , Margaretha Leon Farah
Published: March 2022

This study aims to measure the company's performance based on Economic Value Added (EVA). The independent variables are Investment Capital, Return on Assets, Fixed Assets, Rate of Return on Fixed Assets, and Level Debt. This study uses data from 25 manufacturing companies listed on the Indonesia Stock Exchange over the 2016-2019 period. This study shows a significant negative effect of Investment Capital and Debt Level on EVA. The variable rate of return on fixed assets has a substantial impact on EVA, and there is no significant effect of the return on assets and fixed assets on EVA. Thus, it is expected that financial managers can increase profits and reduce debt to increase EVA.
PERANCANGAN MESIN CNC (COMPUTER NUMERICALY CONTROL) MINI PLOTTER BERBASIS ARDUINO
Authors: Rahman Helmi Syaiful , Fitrianto Rahmad Iwan , Soleh Alfa
Published: March 2022

CNC (computer numerical control) adalah pembaruan mesin perkakas yang telah ada didunia industri mengikuti perkembangan teknologi karena dianggap mesin perkakas sebelumnya kurang efektif dari segi waktu dan biaya. CNC merupakan sistem otomatisasi mesin perkakas yang dioperasikan oleh perintah dan diprogram secara abstrak dan disimpan melalui media penyimpanan, hal ini berlawanan dengan kebiasaan mesin perkakas sebelumnya, dimana mesin perkakas biasanya dikontrol dengan putaran tangan atauotomatisasi sederhana. Pada proyek akhir ini, dirancang suatu alat CNC sederhana yang dapat digunakan engraving atau dengan istilah lain untuk menggambar suatu pola pada bidang tertentu secara otomatis. Desain yang telah digambar melalui personal computer akan dikonversi dalam bentuk G-Code. Sebelum data dikirim ke mikrokontroler, data akan dikonversi terlebih dahulu ke dalam bahasa pemrograman mikrokontroler. Selanjutnya mikrokontroler akan menerima masukan data digital dari personal komputer melalui komunikasi UART. Mikrokontroler akan membaca data yang telah ditransferkan oleh personal komputer, data yang dibaca merupakan unrtuk menaikkan/menurunkankan pena dan memberi logika pada driver motor stepper. Dari data yang diterima oleh driver motor stepper, data digunakan sebagai penggerak kedua motor stepper, dan terbentuk pola pada bidang sesuai desain. Diharapkan dengan adanya CNC sederhana ini menjawab permasalahan yang ada di dunia industri dari segi waktu dan biaya yang dikeluarkan. CNC membuat pola pada bidang secara cepat, serta modern dan lebih baik dibandingkan mesin perkakas sebelumnya yang menggunakan putaran tangan atau otomatisasi sederhana
Features of modeling a highly efficient multistage vapor compression heat pump unit
Authors: Antipov Yuri A. , Shatalova Irina I. , Shkarin Kirill V. , Lapin Mikhail V. , Sokolov Dmitry A. , Grinin Artem O. , Toptygin Kirill P.
Published: March 2022

The increase in the cost of fuel and energy resource and the deterioration of the environment from the combustion of traditional fossil fuel, have led to a great interest in energy-saving technology by using secondary energy resources in the thermal energy of industrial, housing and communal services using heat pump units in Russia and abroad. This paper analyzes the well-known two-stage heat pump units, and reveals their advantages in comparison with single-stage. The modeling of a highly efficient multistage vapor compression heat pump unit is proposed. Moreover, a method for calculating a multistage heat pump unit with a high coefficient of performance is presented. In addition, an example of calculating the thermodynamic cycle of a four-stage heat pump unit is presented. The influence of the number of stages on the increase in coefficient of performance in relation to a single-stage heat pump unit, the effect of the temperature difference between the temperature of the high-potential heat source and the temperature of the low-potential heat source on the coefficient of performance were analyzed. In addition, the influence of the initial value of the temperature of the high-potential heat source before heating during the course in the heat pump unit on the value of coefficient of performance for a different number of stages is analyzed under the condition of a constant difference between the heating temperature of the high-potential heat source at the outlet of the heat pump unit and the temperature of the low-potential heat source.
Book Review: Arzamasov, A.A. 2021. Literature of the Peoples of Russia: Literature of the Peoples of the Far North and the Far East: a Textbook for Universities. Moscow: Yurayt Publ., 248 p.
Authors: Kuchukova Zukhra Akhmetovna , Berberova Liana Burkharovna
Published: March 2022

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Multilingual Literature of the United States
Authors: Kellman Steven
Published: March 2022

Like the Russian Federation, the United States is a multilingual, multicultural society. A nation of immigrants and indigenous peoples, it has produced a rich body of literature in dozens of languages in addition to English that scholars have only in recent decades begun to pay attention to. Of particular note are texts in Spanish, Yiddish, Chinese, French, Hebrew, German, Arabic, Norwegian, Welsh, Greek, Turkish, Italian, Korean, Polish, Portuguese, Russian, Vietnamese and numerous American Indian languages. In this paper we observe the most significant texts of multilingual American literature. The corpus of literary works shows us, that despite Americans pervasive and enduring xenolinguaphobia - aversion to other languages - the United States, like other large countries, is a heterogeneous amalgam. Ignoring the variety of works written in languages other than English impoverishes the national culture and handicaps serious readers.
Bacha Boy in Russian Cultural Reception
Authors: Shafranskaya Eleonora Fedorovna , Garipova Gulchira Talgatovna
Published: March 2022

The article examines the type of culture, the institution that the Russian colonialists faced upon their arrival in the Turkestan region in the ХIХth century - the art of bacha boys. The mismatch of mentality - European and Asian - gave rise to rejection of this institution among the newcomers, who took key administrative positions and charted a course to fight Bachism. The actual destruction of the bacha boys falls on the Soviet period (the play Ecstasy with the Pomegranate from the repertoire of the Ilkhom Theater reflects this process). The authors of the article trace the growing discourse associated with rejection of bacha boys in Russian publicism (articles and fragments of memoirs by V.V. Vereshchagin, N.S. Lykoshin, D.N. Logofet and others), and also analyze the points of view of a number of Russian artists and writers that does not coincide with the official position (N.N. Karazin, V.G. Yan, Usto Mumin, E. Alennik). In the process of reasoning the authors come to the conclusion that the art of bachа boys was organic for Central Asian culture, it correlates with Sufi practices. The article presents arguments from the judgments of Islamic theologians, Russian Islamic scholars, and the Sufi poet Jalaladdin Rumi According to the authors, the so-called evidence-based practice of prerevolutionary persecutors of вacha boys for their alleged immorality is based on rumors and speculation, with which folklore reality usually works, mythologizing this or that phenomenon. N.N. Karazin writes the novel Atlar precisely in the algorithm of the rehabilitation of the вacha boys.
Russian-German Chanson as a Product of Emigration
Authors: Seifert Elena Ivanovna
Published: March 2022

The theory of chanson as a creative direction has not been sufficiently developed, although the study of chanson has undoubtedly been strengthening its positions recently. Researchers perceive chanson broadly (songs of the direction of urban song folklore) and narrowly (thieves lyrics). The purpose of the research is to study the Russian-German chanson, the tasks are to observe the works of Vadim Kuzema and Viktor Gagin, a multifaceted analysis of the lyric cycle of Sonya Jahnke From a Song Notebook. The legitimacy of the allocation of the Russian-German chanson is confirmed by the attempt of the national-geographical division of the Russian-speaking chanson, proposed by M. Dyukov. Russian-German chanson is a phenomenon that formed during the third stage of mass migration, that is, it fully takes into account all the genetic layers of the subcultural ethnos. S. Janke, in her stylization as a thug chanson song, concerns various aspects of the life and life of Russian Germans in Germany. The author of the article applies structural-descriptive, historical-typological and comparative-historical research methods. The research results can be applied to the entire RussianGerman chanson. The lyrical hero suffers from marginality and seeks to grow into a new and still alien society for him. The clear difference between Russian-German chanson and Russian is in a special collective subject (a type of Russian German) striving to become related to the world that alienates him (as opposed to the hero of the Russian thug chanson cultivating the world of outcasts). The asocial character of the hero of the Russian-German chanson is fundamentally different from the asocial character of the hero of the Russian chanson. Comprehension of the Russian-German chanson reveals a paradox: the appeal of Russian Germans to a marginal thug song is nothing more than an attempt to free themselves from the marginality of their ethnic group. Russian-German stylization under the thieves song is not distinguished by romance: the ethnic picture of Russian Germans is not characterized by the typically Russian opposition of high and low.
The Function of Introductions in Dostoevsky’s Work (About L. Bagby’s Book)
Authors: Podosokorsky Nikolay N.
Published: March 2022

The review analysis the main theses contained in the monograph by Lewis Bagby, American slavicist, Professor Emeritus of Russian literature and language at the University of Wyoming, First Words: On Dostoevsky’s Introductions, that researches the functions of prefaces/introductions in Dostoevsky’s literary works. Bagby identifies ten Dostoevsky’s texts (The Village of Stepanchikovo and Its Inhabitants, Notes from the House of the Dead, Winter Notes on Summer Impressions, Notes from the Underground, “Bobok”, The Devils, “The Beggar Boy at Christ’s Christmas Tree”, “The Peasant Marey”, “A Gentle Creature”, and The Brothers Karamazov) and attempts to analyze the introductions using Gérard Genette’s typology. This classification seems ill-suited to the task of describing and studying the introductions in Dostoevsky’s work. The review points out inconsistencies and controversial moments in the book.
The Return of The Adolescent
Authors: Yuryeva Olga О.
Published: March 2022

The review is dedicated to a new collective work devoted to the study of Dostoevsky’s novel The Adolescent. This unique publication presents articles by Russian and foreign scholars that reflect the main trends in the perception and interpretation of the novel, and questions concerning textual studies. This fundamental work will determine the orientations of the critical literature about the novel for many decades.
“Do Not Blame Anyone...” The Suicide Note as a Trait of the Character’s Image
Authors: Saraskina Liudmila I.
Published: March 2022

The paper analyses the destinies of those characters in Dostoevsky’s novels who resolved to voluntarily part with their lives, committing suicide. The author tries to understand the ideological and practical motives, as well as the concomitant declarations and immediate reasons for these gestures. It is asserted that in every case the decision to annihilate oneself is taken with great effort and that life instinct persists in one’s heart till the very last instants which remain a mystery for those who stay alive. In this respect, the case of Kirillov in The Possessed is unique. The suicide notes, letters, or diaries, which self-destroyers write either in advance or during the last moments of their life, often contain the formula: “Do not blame anybody, I did it myself”. Seems these words can two different purposes. The phrase can serve as a kind of laissezpasser for people, belonging to one’s environment; however, it can be also a way to settle accounts with some of them (as in the case of Smerdyakov). Some characters in the article are categorized as “latecomers”, i.e. those who could have prevented the suicide but missed the opportunity, as did Arkady Dolgoruky with Kraft. Stavrogin could have saved Matryosha, prevented her suicide, but he did not want to and chose to stay aside and watch with curiosity. This tragic experience later made him write his confession. People close to the would-be self-destroyer usually do not perceive signals from the person who comes to bid adieu, and sometimes the preparation for suicide may be camouflaged through cunning and pretenses (Raskolnikov and Svidrigailov). The suicide message may be sent as a gesture or symbol, as it was for Matryosha or the “Meek One”. The paper is dedicated to the artist A.N. Korsakova who illustrated Dostoevsky’s works for many years and, in the end, shared the destiny of those Dostoevsky’s characters who voluntarily parted with their lives.
TINJAUAN SADD AZ>-Z|ARI<â€™AH TERHADAP PRAKTIK JUAL BELI PLAT NOMOR KENDARAAN BERMOTOR (Studi Kasus di Desa Kedungan, Kecamatan Pedan, Kabupaten Klaten)
Authors: Nugraini Kirana Hari
Published: March 2022

Every act that is consciously carried out by someone must have a certain clear purpose, without questioning the intended action is good or bad, brings benefits or brings mudharat. Not a few people have succeeded in opening new jobs by becoming a number plate seller, this situation often occurs in one village in Klaten Regency, namely in Kedungan Village. The number plate sellers emphasize as much profit as possible and ignore the moral and benefit of the people. This research uses the type of field research with data collection methods used are interviews, observation and documentation. The data obtained were analyzed in a descriptive-qualitative way using deductive reasoning. The results of this study indicate that the practice of buying and selling motorized vehicle license plates in terms of harmony and the conditions of sale and purchase that do not meet the requirements that the goods can be used for prohibited acts. And if it is reviewed from sadd az-z|ari>â€™ah then the practice of buying and selling number plates is better not done because it brings a lot of interpretations compared to its benefit.Keywords: Sadd Az-z|ari>â€™ah;Â Buy and Sell; License Plate.Â AbstrakSetiap perbuatan yang sadar dilakukan oleh seseorang pasti mempunyai tujuan tertentu yang jelas, tanpa mempersoalkan perbuatan yangÂ  dituju itu baik atau buruk, mendatangkan manfaat atau menimbulkan mudharat. Tidak sedikit masyarakat berhasil membuka lahan pekerjaan baru dengan menjadi penjual plat nomor, keadaan ini banyak terjadi pada salah satu desa di Kabupaten Klaten, yaitu di Desa Kedungan. Para penjual plat nomor lebih menitikberatkan kepada keuntungan sebanyak-banyaknya dan mengabaikan sisi moral dan kemaslahatan umat. Penelitian ini menggunakan jenis penelitian lapangan dengan metode pengumpulan data yang digunakan adalah wawancara, observasi dan dokumentasi. Data yang diperoleh dianalisis dengan cara deskriptif-kualitatif menggunakan penalaran deduktif. Hasil dari penelitian ini menunjukkan bahwa praktik jual beli plat nomor kendaraan bermotor ditinjau dari rukun dan syarat jual beli bahwa belum memenuhi syarat yaitu barangnya dapat dimanfaatkan untuk perbuatan terlarang. Serta jika ditinjau dari sadd az-z|ari>â€™ah maka praktik jual beli plat nomor itu lebih baik tidak dilakukan karena banyak mendatangkan kemafsadatan dibandingkan kemaslahatannya.Kata Kunci : Sadd Az-z|ari>â€™ah, Jual Beli, Plat Nomor.
Prevalence of pre-eclampsia and adverse pregnancy outcomes in women with pre-existing cardiomyopathy: a multi-centre retrospective cohort study.
Authors: Ormesher Laura , Vause Sarah , Higson Suzanne , Roberts Anna , Clarke Bernard , Curtis Steph , Ordonez Victoria , Ansari Faiza , Everett Thomas , Hordern Claire , Mackillop Lucy , Stern Victoria , Bonnett Tessa , Reid Alice , Wallace Suzanne , Ese Ebruba , Douglas Hannah , Cauldwell M. , Reddy Maya , Palmer Kirsten , Simpson Maggie , Brennand Janet , Minns Laura , Freeman Leisa , Murray Sarah , Mary Nirmala , Castleman James , Morris Katie , Haslett Elizabeth , Cassidy Christopher , Johnstone Edward , Myers Jenny
Published: March 2022

Objective: To determine the prevalence of pre-eclampsia and fetal growth
restriction (FGR; <3rd centile) in women with pre-existing
cardiac dysfunction. Design: Retrospective cohort study. Setting:
Maternity units in UK and Australia. Population: Pregnant women with
impaired left ventricular ejection fraction<55%. Methods:
Routine clinical data, including medical history and pregnancy outcome
were collected retrospectively. Main Outcome Measures: Pre-specified
outcomes included pre-eclampsia and FGR prevalence in women with
pre-existing cardiac impairment, compared with the general population;
and the relationship between pregnancy outcome and pre-pregnancy cardiac
phenotype. Results: In this cohort of 282 pregnancies, pre-eclampsia
prevalence was not significantly increased (4.6% [95% C.I
2.2-7.0%] versus population prevalence of 4.6% [95% C.I.
2.7-8.2], p=0.99); 12/13 of these women had additional
obstetric/medical risk factors. However, prevalences of preterm
pre-eclampsia (<37 weeks) and FGR were increased (1.8% versus
0.7%, p=0.03; 15.2% versus 5.5%, p<0.001, respectively).
Neither systolic nor diastolic function correlated with pregnancy
outcome; however, left ventricular mass index (LVMi) weakly correlated
with pre-eclampsia (5g/m2 increase: OR 1.18 [95% C.I. 1.01-1.38],
p=0.04). Antenatal ß blockers (n=116) were associated with lower
birthweight Z score (adjusted difference -0.33 [95% C.I. -0.63-
-0.02], p=0.04). Conclusions: This study demonstrated a modest
increase in preterm pre-eclampsia and significant increase in FGR in
women with cardiac dysfunction. These results do not support a causal
relationship between cardiac dysfunction and pre-eclampsia, especially
accounting for the background risk status of the population. The
mechanism underpinning the relationship between cardiac dysfunction and
FGR merits further research but could be influenced by concomitant ß
blocker use.
Geographical contrasts of Y-chromosomal haplogroups from wild and domestic goats reveal ancient migrations and recent introgressions
Authors: Consortium Vargoats , Nijman Isaäc , Rosen Benjamin , Bardou Philippe , Faraut Thomas , Cumer Tristan , Daly Kevin , Zheng Zhuqing , Cai Yudong , Asadollahpour Hojjat , Cinar-Kul Bengi , Zhang Wei-Yi , e guangxin , Ayin A , Baird Hayley , Bakhtin Meirat , Balteanu Valentin , Barfield Diana , Berger Beate , Blichfeldt Thor , Boink Geert , Bugiwati Sri Rachma , Cai Zexi , Carolan Sean , Clark Emily , Curik Vladka Cubrić , Dagong Muhammad , Dorji Tashi , Drew Louise , Guo Jiazhong , Hallsson Jón , Horvat Simon , Kantanen Juha , Kawaguchi Fuki , Kazymbet Polat , khayatzadeh Negar , Kim Namshin , Shah Manoj Kumar , Liao Yuying , Martinez Amparo , Masangkay Joseph , Masaoka Maho , Mazza Raffaele , McEwan John , Milanesi Marco , Faruque Md Omar , Nomura Yuto , Ouchene-Khelifi Nadjet-Amina , Pereira Filipe , Sahana Goutam , Salavati Mazdak , Sasazaki Shinji , SILVA Anne DA , Simčič Mojca , Soelkner Johann , Sutherland Alison , Tigchelaar Johannes , Zhang Hongping , Consortium Econogene , Marsan Paolo Ajmone , Bradley Daniel , Colli Licia , Drögemüller Cord , Jiang Yu , Lei chuzhao , Mannen H , Pompanon Francois , TOSSER-KLOPP GWENOLA , Lenstra Johannes A.
Published: March 2022

By their paternal transmission, Y-chromosomal haplotypes are sensitive
markers of population history and male-mediated introgression. Previous
studies identified biallelic single-nucleotide variants in the SRY, ZFY,
DDX3Y genes, which in domestic goats identified four major Y-chromosomal
haplotypes Y1A, Y1B, Y2A and Y2B with a marked geographic partitioning.
Here, we analyze whole-genome sequences of 386 domestic goats from 75
modern breeds and 7 wild goat species that were generated by the
VarGoats goat genome project. Phylogenetic analyses indicated domestic
haplogroups corresponding to Y1B, Y2A and Y2B, respectively, whereas Y1A
is split into Y1AA and Y1AB. All five haplogroups were detected in 26
ancient DNA samples from southeast Europe or Asia. Haplotypes from
present-day bezoars are not shared with domestic goats and are attached
to deep nodes of the trees and networks. Haplogroup distributions for
180 domestic breeds indicate ancient paternal population bottlenecks and
expansions during the migrations into northern Europe, eastern and
southern Asia and Africa south of the Sahara. In addition, sharing of
haplogroups indicates male-mediated introgressions, most notably an
early gene flow from Asian goats into Madagascar and the crossbreeding
that in the 19th century resulted in the popular Boer and Anglo-Nubian
breeds. More recent introgressions are those from European goats into
the native Korean goat population and from Boer goat into Uganda, Kenya,
Tanzania, Malawi and Zimbabwe. This study illustrates the power of the
Y-chromosomal variants for reconstructing the history of domestic
species with a wide geographic range.
Changes in lung clearance index in children with cystic fibrosis -- guidance for clinical practice
Authors: Frauchiger Bettina , Ramsey Kathryn , Usemann Jakob , Kieninger Elisabeth , Casaulta Carmen , Sirtes Daniel , Yammine Sophie , Spycher Ben , Moeller Alexander , Latzin Philipp
Published: March 2022

Rationale The lung clearance index (LCI) is increasingly being used in
the clinical surveillance of patients with cystic fibrosis (CF).
However, there are limited data on long-term variability and clinically
relevant changes in LCI during routine clinical surveillance. Objectives
To evaluate long-term variability of LCI and propose a threshold for a
clinically relevant change. Methods Children with CF aged 4-18 years
performed LCI measurements every three months as part of routine
clinical surveillance during 2011-2020 in two centers. The variability
of LCI during periods of clinical stability was assessed using
mixed-effects models and was used to identify thresholds for clinically
relevant changes. Results Repeated LCI measurements of acceptable
quality (N= 858) were available in 100 patients with CF. Variability of
repeated LCI measurements over time expressed as coefficient of
variation (CV%) was 7.4%. The upper limit of normal (ULN) for relative
changes in LCI between visits was 19%. Conclusion We report the
variability of LCI in children and adolescents with CF during routine
clinical surveillance. According to our data, a change in LCI beyond
19% may be considered clinically relevant. These findings will help
guide clinical decisions according to LCI changes.
Follow-up of hen’s egg allergic children: investigation of factors that influence the reevaluation of tolerance development
Authors: BEYER Kirsten , Baek Paul , Dobbertin-Welsch Josefine , Kalb Birgit , Trendelenburg Valérie , Tschirner Sebastian , Veit Meike , Yürek Songül
Published: March 2022

Background: In order to determine tolerance development in
hen’s egg (HE) allergic children, international guidelines recommend an
oral food challenge after 6-24 months. This study aimed to assess
whether parents follow this advice and factors that influence their
decision. Methods: A follow-up of 158 challenge-proven HE
allergic children was performed. Families who did not come to a
rechallenge were contacted by phone and a standardized survey relating
to the current allergy status was conducted. Logistic regression models
were used to assess the effect of clinical and laboratory
characteristics on the reevaluation of the allergy status.
Results: 35% of the HE-allergic children conducted a
rechallenge in a hospital, 27% continued avoiding HE without
reevaluation and 11% performed a “home-testing” with HE. The odds
ratio for patients to test for HE tolerance at home instead of in a
hospital increased 7.94 times (CI:2.31-27.31) for every decrease in the
severity score at the initial challenge, and 3.24 times (CI:1.26-8.33)
for every decrease of the baseline specific IgE CAP-class. Tolerance of
heated HE prior to reevaluation was most frequent in the home-tested
(100%) and was more frequent in patients, who continued avoidance
(68%) compared to those, who were rechallenged (44%).
Conclusions: Our data suggest an association between reaction
severity as well as specific IgE levels at initial food challenge and
the choice of families whether and how to evaluate natural tolerance
development in their HE-allergic child. Individualized management may be
needed in order to achieve safe and effective medical care for these
patients.
ECO LOGICAL BEHAVIOUR OF GENERATION Z IN POLAND
Authors: Jaciow Magdalena , Wójciak Mirosław , Poradowska Konstancja
Published: March 2022

The purpose of this article is to present research on the ecological behaviour of Generation Z in Poland. The research was conducted with the use of CAWI techniques on a sample of 260 Polish consumers from Generation Z. With use of the Lance-Williams-Ward’s agglomerative methods, three homogenous groups of Gen Z consumers were identified on the basis of self-evaluation of ecological behaviour and on the behaviour of their surrounding environment (household and friends), i.e. pro-ecological, ecological, and non-ecological. By means of non-parametric analysis of variances (Kruskal-Wallis test) and post hoc analysis, the significance of differences in the values of the analyzed variables was assessed, indicating differences in the ecological behaviors of the selected groups. The results of the analysis show that there are differences in the frequency of ecological behaviours that are undertaken within the selected groups.
FOREIGN TRADE OF MILK AND DAIRY PRODUCTS IN THE EUROPEAN UNION
Authors: Zalewski Krzysztof , Bórawski Piotr , Dunn James W.
Published: March 2022

The objective of the paper is to present foreign trade of milk and dairy products in the EU. Particular attention is paid to exports and imports of milk and dairy products in the EU and globally. Graphs and tabular and descriptive methods are used to analyze the changes in trade. The analysis of foreign trade focuses mainly on 2020; however, global export of selected dairy products was analyzed for the years 2000–2020. The survey shows the development of trade for milk and dairy products in the EU countries and the world.
Warszawska infrastruktura rowerowa w opinii jej użytkowników
Authors: Posytek Karolina , Klepacki Bogdan
Published: March 2022

W opracowaniu przedstawiono pojęcie i podział transportu miejskiego, którego transport rowerowy jest częścią. Opisano również cechy publicznego transportu rowerowego. Przedstawiono zmiany w ocenie warszawskiej infrastruktury rowerowej w latach 2018–2020, które zostały opracowane na podstawie badań ankietowych. Wykonano także analizę pola sił Warszawskiego Roweru Publicznego, wskazując elementy napędzające oraz hamujące rozwój Veturilo
Pojęcie, znaczenie i pomiar śladu węglowego (carbon footprint)
Authors: Zarczuk Julia , Klepacki Bogdan
Published: March 2022

Celem opracowania było ukazanie problematyki śladu węglowego. Zostało wyjaśnione pojęcie carbon footprint, jego geneza i zakres. Omówiono regulacje prawne, zalety i wady oraz metody szacowania wskaźnika. Zaprezentowany został wybrany kalkulator emisji CO2 informujący o wpływie na środowisko danego użytkownika w porównaniu do średnich kraju/świata.
Retinoic acid induces hyaluronic acid production through the klotho-mediated EGFR signaling pathway in human epidermal keratinocytes
Authors: Choi Hyangtae , Lee Yonghee , Park Won-seok , Kim Beom , Lee Chang
Published: March 2022

All-trans retinoic acid (RA) is an effective anti-aging chemical substance widely used in skin-care products. RA compromises epidermal differentiation and induces keratinocyte proliferation, causing hyaluronic acid production through mechanisms that are not completely understood. Klotho protein causes the differentiation of human epidermal keratinocytes. Klotho gene expression is mediated by epidermal growth factor (EGF), which inhibits cell apoptosis in aging-related diseases. The klotho gene causes human aging syndrome, including short lifespan, skin atrophy, and osteoporosis. We investigated the relationship between RA and klotho in epidermal keratinocytes for the first time. In human epidermal keratinocytes, RA induced klotho gene expression. Treatment with both RA and recombinant klotho induced hyaluronic acid production in human epidermal keratinocytes. However, in klotho small interfering RNA (siRNA)-transfected keratinocytes, RA produced less hyaluronic acid than in the control group, indicating that RA may partially regulate hyaluronic acid production through a klotho-dependent pathway. Knockdown of klotho gene expression inactivated the EGFR-extracellular signal-regulated kinase (ERK) signaling pathway, which is involved in hyaluronic acid production. We concluded that the effect of RA on hyaluronic acid production is partly regulated through the klotho-mediated EGFR signaling pathway in human epidermal keratinocytes.
Association Between Diabetes and the Risk of Kidney Cancer: Systematic Review and Meta-Analysis
Authors: Bonilla-Sanchez Andrés , Rojas-Munoz Jenny , Garcia-Perdomo Herney Andrés
Published: March 2022

Diabetes is a risk factor for several types of cancer, but the specific relationship
between diabetes and kidney cancer is not well understood. We conducted a
search strategy in scientific databases for case-control and cohort studies on
this topic. We analyzed 17 studies and found that diabetes was significantly
associated with the risk of developing kidney cancer and that this risk was slightly
stronger for women and for people living in Asia. These findings were not
influenced by obesity, cigarette smoking, or hypertension. We conclude that diabetes
is an independent risk factor for the development of kidney cancer.
Participant acceptability of digital footprint data collection strategies: an exemplar approach to participant engagement and involvement in the ALSPAC birth cohort study.
Authors: Shiells Kate , Di Cara Nina , Skatova Anya , Davis Oliver , Haworth Claire , Skinner Andy , Thomas Richard , Tanner Alastair , Macleod John , Timpson Nicholas , Boyd Andy
Published: March 2022

IntroductionDigital footprint records -- the tracks and traces amassed by individuals as a result of their interactions with the internet, digital devices and services -- can provide ecologically valid data on individual behaviours. These could enhance longitudinal population study databanks; but few UK longitudinal studies are attempting this. When using novel sources of data, study managers must engage with participants in order to develop ethical data processing frameworks that facilitate data sharing whilst safeguarding participant interests.
ObjectivesThis paper aims to summarise the participant involvement approach used by the ALSPAC birth cohort study to inform the development of a framework for using linked participant digital footprint data, and provide an exemplar for other data linkage infrastructures.
MethodsThe paper synthesises five qualitative forms of inquiry. Thematic analysis was used to code transcripts for common themes in relation to conditions associated with the acceptability of sharing digital footprint data for longitudinal research.
ResultsWe identified six themes: participant understanding; sensitivity of location data; concerns for third parties; clarity on data granularity; mechanisms of data sharing and consent; and trustworthiness of the organisation. For cohort members to consider the sharing of digital footprint data acceptable, they require information about the value, validity and risks; control over sharing elements of the data they consider sensitive; appropriate mechanisms to authorise or object to their records being used; and trust in the organisation.
ConclusionRealising the potential for using digital footprint records within longitudinal research will be subject to ensuring that this use of personal data is acceptable; and that rigorously controlled population data science benefiting the public good is distinguishable from the misuse and lack of personal control of similar data within other settings. Participant co-development informs the ethical-governance framework for these novel linkages in a manner which is acceptable and does not undermine the role of the trusted data custodian.
Evaluation of the Corrosion Rate at the Bottom of the above – Ground Tank for Storage of Petroleum Products
Authors: Povse Ales , Skale Sasa , Vojvodič Tuma Jelena
Published: March 2022

A study of corrosion in steel fuel storage tanks, which failed after several years of operation highlighted intense pitting and microbiological corrosion. Significantly higher corrosion rates were found than would be expected with normal seawater corrosion. Therefore, the established methodology for predicting the remaining service life of tanks is also questionable. The aim of the study was to evaluate the actual corrosion rates at the bottom of the petroleum product tank. For this purpose, we adapted the established laboratory methods for evaluating the corrosion rate to perform field measurements. The observed corrosion rates in the tank are higher than the currently known values.
Numerical Simulation of Effects of Velocity and Diffusion Coefficient on Concentration of Contaminants in the Fluid Flow
Authors: Langat K. , Shichikha J. , Bitok J.
Published: March 2022

The study developed and implemented Implicit and explicit schemes for solving convection –diffusion equation in one dimension on concentration of contaminant in a fluid flow. The stability of the scheme was analyzed and the accuracy of the solution of the contaminant transport equation was validated by exact available solution. Graphical presentation of the solution for varying velocity and diffusion coefficient was given. The explicit method (EM) involved one unknown on lift hand side (LHS) while implicit method (IM) involved several unknowns on LHS. The study analyzed the effect of velocity and diffusion coefficient on concentration of contaminant in a fluid flow. The developed schemes were solved numerically using MATLAB was to generate the result and in analysis of results. Results showed that concentration of contaminants increased inversely with velocity and directly to diffusion coefficient. Therefore, for proper treatment of water for example, it is necessary to reduce the flow velocities to reduce the trend of contaminants. As Velocity increases the concentration of contaminant decreases and as diffusion coefficient increases the concentration of contaminant increases.
Survey Exploring Public Knowledge of Cardiovascular Disease Prevention in Cheshire, UK
Authors: Harfoush Allam , Hamdallah Hanady
Published: March 2022

Background: Cardiovascular disease (CVD) is considered one of the leading causes of death in the UK, and annual statistical reports show that some areas in the north of England has one of the highest death rates due to CVD in the country.

Methods: A cross-sectional study was conducted in Cheshire to evaluate public knowledge and determine the most popular methods to receive updated information regarding CVD risk factors.

Results: 269 participants were eventually eligible for the analysis. The overall knowledge score was relatively high (median score = 12/12, IQR = 1); patients with a history of CVD or diabetes mellitus showed a lower level of knowledge compared with healthy individuals (P = 0.007). On the other hand, the internet was the most popular method to receive updated cardiovascular disease information (70% of the sample). Participants showed a tendency to visit official and governmental websites to obtain the needed information, and Google was the most selected platform in all age groups.

Conclusions: There might be a need to invest more time in providing CVD patients with sufficient instructions to ensure their adherence to secondary prevention measures. Also, more time and resources should be invested in developing official and governmental public health websites.
Meningkatkan Hasil Belajar Siswa Menggunkan Model Pembelajaran Project Based Learning (PjBL) Pada Mata Diklat Pemeliharaan Kelistrikan Kendaraan Ringan Kelas XI Program Studi Teknik Otomotif Kendaraan Ringan SMK Negeri 1 Padang
Authors: Primadana Teguh , Maksum Hasan , Wagino Wagino
Published: March 2022

This study aims to improve student learning outcomes of SMK Negeri 1 Padang by using the Project Based Learning (PjBL) learning model. The research is Classroom Action Research using The George Lucas Educational Foundation model. The results of this study indicate an increase in student activity by 21.9% and an increase in student learning outcomes with the average value increasing from 60.6 to 78.1 in cycle 1 and 86.7 in cycle 2, and the number of students who graduate increased from 6 people to 22 people in cycle 1 and 32 people in cycle 2.  Project Based Learning (PjBL) is effective in improving the learning outcomes of TKR Class XI students at SMK Negeri 1 Padang in the subject of Electrical Maintenance course.

Penelitian ini bertujuan untuk meningkatkan hasil belajar siswa SMK Negeri 1 Padang dengan menggunakan model pembelajaran Project Based Learning (PjBL). Pada penelitian merupakan penelitian tindakan kelas (PTK) atau Classroom Action Research menggunakan model The George Lucas Educational Foundation yang terdiri atas 2 siklus. Hasil penelitian ini menunjukkan terjadinya peningkatan keaktifan siswa sebesar 21,9% dan terjadi peningkatan hasil belajar siswa dengan nilai rata-rata meningkat dari 60,6 menjadi 78,1 pada siklus 1 dan 86,7 pada siklus 2, serta jumlah siswa yang lulus meningkat dari 6 orang menjadi 22 orang pada siklus 1 dan 32 orang pada siklus 2. Project Based Learning (PjBL) efektif untuk meningkatkan hasil belajar siswa TKR Kelas XI SMK Negeri 1 Padang pada mata diklat Pemeliharaan Kelistrikan.