bluuebunny/crossref_metadata_2025 huggingface dataset:
Computed Tomography for the Nondestructive Testing of Additive Manufactured Components: Opportunities and Limitations
Authors: Schulenburg Lennart
Published: June 2021

The additive manufacturing (AM) process has grown from university research laboratories into a production process for complex-shaped components. Due to the uniqueness of the manufacturing process, new challenges have arisen regarding process control, quality assurance, and surface finishing. This paper will show how the nondestructive radiographic testing (RT) technique computed tomography (CT) can make a valuable contribution to quality assurance at each step of the AM process. The use of CT is demonstrated using an example of chrome-nickel steel nozzles manufactured using the laser powder bed fusion (LPBF) process. The surface of the nozzles is then reworked with the Hirtisation process, a trademarked part finishing technology that is based on a combination of electrochemical pulse methods, hydrodynamic flow and particle assisted chemical removal, and surface treatment. In addition to the already known use of CT for detecting internal discontinuities, CT can be used to ensure sufficient wall thickness, measure internal channel surface roughness, and gauge the geometrical correctness of parts. In this paper, it is demonstrated how to use this RT technique to optimize the design and production process during the component development phase.
Additív gyártástechnológiák katonai alkalmazásának vizsgálata, különös tekintettel a katonai elektronika területére
Authors: Németh András , Gál Bence
Published: June 2021

Az innovatív, forradalmi technológiakéntszámon tartott 3D nyomtatás lehetőségek széles skáláját biztosítja a haderők számára. A tanul mány célja, hogy tudományos módszerekkel vizsgálva a szakterület sajátosságait, komplex képet nyújtson a különböző additív gyártási módszerek funkciójáról, a felhasználható alapanyagokról, rávilágítva a hadiipari és haditechnikai alkalmazások széles spektrumára, melyek könnyen lehet, hogy a jövőben alapjaiban változtatják majd meg korunk hadviselésének technikai támogatását.
A Katonai Logisztika Alapképzési Szak Páncélos és gépjárműtechnikai modulján végzett hallgatók tanulmányi eredményei összehasonlítva a korábbi képzésekkel
Authors: Gyarmati József , Vég Róbert László
Published: June 2021

A cikk egy korábbi tanulmány kutatásának a folytatása, ahol a címben megnevezett modulszakmai tartalmának a változása lett megvizsgálva az elmúlt másfél évtized három különböző képzési formájában. Jelen tanulmány azt vizsgálja, hogy a hallgatók milyen minőségben tudták teljesíteni az egyes képzések során a tantárgyak által támasztott követelményeket.
Breathing And Stretching Exercises Affect The Decrease in The Intensity of Leg Cramp Pain
Authors: Achwan Achwan , Laksono Abdurahman B.B.
Published: June 2021

Leg cramps are a common side effect of intradialysis CKD patients. Preventing intradialysis cramping pain can improve quality of life. Breathing and stretching exercises are non-pharmacological treatments for cramping pain. The purpose of this study was to prove the effect of breathing and stretching exercises on changes in the intensity of leg cramps in hemodialysis patients at the Haji Jakarta Hospital in 2018. This study was a quasi-experimental study with a two-group pre-post test research design. The sample was selected by purposive sampling, a sample of 34 patients. The intensity of muscle cramps was measured using the Numeric Rating Scale. The results of the analysis using the paired sample T-test. The results showed that the intervention group had a P-value = 0.01 and the control group had a P-value = 0.055, meaning that there was a difference in mean the intensity of cramping pain before and after breathing and stretching exercises was compared, so it was concluded that there was an effect of breathing and stretching exercises on the intensity of intradialysis leg cramps. Patients are advised to breathing and stretching exercises regularly, light exercise, eat and drink diet.
Integrated Methodology for Physical and Economic Assessment of Coastal Interventions Impacts
Authors: Lima M. , Coelho C.
Published: June 2021

Due to economic, environmental, and social interest of coastal areas, together with their erosion problems, different coastal management strategies can be considered, with different physical (shoreline evolution) and economic (net present value, ratio benefit-cost, break-even point) consequences and impacts. Therefore, this work presents an integrated methodology that aims to compare and discuss the most promising coastal intervention scenarios to mitigate erosion problems and climate change effects, considering costs and benefits related to each intervention. The proposed methodology takes a step forward in assessing the coastal erosion mitigation strategies, incorporating three well-defined and sequential stages: shoreline evolution in a medium-term perspective; structures pre-design; and a cost-benefit assessment. To show the relevance of the methodology, a hypothetic case study and several intervention scenarios were assessed. In order to mitigate costal erosion two different situations were analyzed: the reference scenario and the intervention scenarios. 34 intervention scenarios were proposed and evaluated to mitigate the erosion verified. Depending on the parameter considered (reduce erosion areas, protect the full extension of urban waterfronts, improve the economic performance of the intervention by increasing the net present value, the benefit-cost ratio or decreasing the break-even time), best results are obtained for different scenarios. The definition of the best option for coastal erosion mitigation is complex and depends on the main goal defined for the intervention. In conclusion, costs and benefits analysis are demanded and it is considered that the proposed methodology allows choosing better physical and economic options for future coastal interventions, helping decision-making processes related to coastal management.
Confini urbani, confini di guerra, confini di ricostruzione. I regimi proprietari come motore dei processi insediativi della ricostruzione
Authors: Galli Jacopo
Published: June 2021

Le attuali condizioni delle citta della MENA region pongono serie domande sui processi di progettazione in termini di possibili strategie di ricostruzione. Le condizioni di tabula rasa offrono molte possibilita, ma la struttura della proprieta e un grave ostacolo a una ricostruzione sostenibile. L'articolo analizza l'evoluzione dei confini urbani nelle citta siriane prima, durante e dopo la guerra, ripercorrendo i processi di metamorfosi urbana dettati da cause economiche, sociali e storiche.
Progetti per il recupero culturale. Strategie per il paesaggio urbano storico della città antica di Aleppo
Authors: Annalinda Neglia Giulia
Published: June 2021

Le distruzioni traumatiche che continuano a interessare i centri storici delle regioni mediorientali, ne hanno danneggiato la coerenza morfologica e sociale. Focalizzandosi sul recupero del paesaggio urbano nel suo complesso, questo scritto intende prospettare strategie progettuali per la rigenerazione della Citta antica di Aleppo basate su metodologie che coinvolgono la comunita locale nei processi di ricostruzione corale della societa urbana, delle case e del recupero degli spazi aperti.
Chi bada alle badanti? La specialità del lavoro domestico alla prova del Covid-19
Authors: de Martino Claudio
Published: June 2021

Il saggio propone una riflessione sulla specialità del lavoro domestico, a partire dalla sua defi-nizione legislativa e dalla tecnica normativa di tipo sottrattivo che caratterizza i diversi istituti, soffermandosi poi sulle ragioni della vasta diffusione del lavoro irregolare. L'A. si sofferma, inoltre, sulle novità offerte dalla legislazione emergenziale e conclude con alcune proposte per il superamento dell'irregolarità nel settore, con un particolare focus sulla tutela processuale.
Laura Zanetti. Note sulla vita di una donna e di una resistente
Authors: Boneschi Barbara
Published: June 2021

Note biografiche concernenti Laura Zanetti, comandante dell'Intendenza della Brigata GL Monte Suello
La formazione dell'identità nell'interazione tra culture
Authors: Özbek Tülay
Published: June 2021

La formazione dell'identità dei bambini che sono cresciuti entro due o più background cul-turali è caratterizzata da un ampio spettro di identificazioni divergenti. Questo ha un impatto specifico sulla loro struttura psichica, visto che ci sono identificazioni con almeno due back-ground etnicoreligiosi e due grandi gruppi, che possono interferire col sentimento di apparte-nenza. Con riferimento ai concetti di formazione dell'identità (Erikson), identificazione (Freud), identificazione col gruppo interno e col gruppo esterno e l'emergenza di un oggetto interno (Davids, Volkan), viene proposto lo svolgersi dello sviluppo di un'identità ibrida e diasporica con almeno tre introietti gruppali per i membri della terza generazione che sono sot-toposti a una socializzazione biculturale. La formazione di un'identità ibrida rende l'Io capace di legare assieme complesse affiliazioni culturali, in modo tale che il soggetto possa sentirsi identico a se stesso nello spazio, nel tempo e nei luoghi. Allo stesso tempo, tutto ciò richiede che il dolore e la destabilizzazione associati al fatto di non avere ciò che originariamente era visto come formazione identitaria, ovverosia il sentimento di appartenere a uno ed uno solo grande gruppo, possa essere tollerata e accettata.
Ideal-tipi di performance management nella pianificazione delle Aziende Sanitarie. Una prima rilevazione empirica a livello nazionale
Authors: Costumato Lorenzo , Scalabrini Fabiana , Bonomi Savignon Andrea
Published: June 2021

I quattro ideal-tipi di performance management (Bouckaert e Halligan, 2008) rappresentano altrettante fasi di un'evoluzione da un approccio non organico e prevalentemente focalizzato sulla rilevazione degli input (performance administration), a uno in cui il ciclo di gestione della performance e completamente integrato nei processi gestionali dell'organizzazione e interagisce con l'ambiente esterno (performance governance). Questi modelli hanno esercitato una decisa influenza sulla letteratura successiva in materia di performance management in ambito pubblico, ma sono stati solo sporadicamente indagati a livello empirico nel contesto sanitario (Halligan et al., 2012; Tenbensel e Burau, 2017). Il presente articolo fornisce un'analisi empirica dei piani della performance 2020-2022 pubblicati dalle ASL italiane, fornendo una risposta alla seguente domanda di ricerca: dopo oltre un decennio dall'adozione del D.Lgs. n. 150 del 2009, verso quale ideal-tipo di performance management sono orientate le Aziende Sanitarie Locali in Italia? Per rispondere a questa domanda, e stato definito un modello di valutazione qualitativa che consente di posizionare ogni ASL sul continuum descritto da Bouckaert e Halligan rispetto a sei ambiti di interesse specifici, frutto dell'incrocio tra quanto definito in letteratura e la normativa vigente sulla gestione del ciclo della performance, al fine di verificare se esiste una traiettoria di avanzamento delle ASL verso il modello performance governance.
Pandemia, un anno dopo. Un contributo di idee alla riforma dei contenuti e dei modelli organizzativi della cura della salute umana
Authors:   Società Italiana di Psiconeuroendocrinoimmunologia - Consiglio Direttivo Nazionale
Published: June 2021

Proposte della Sipnei alla discussione in corso sulla inderogabile riforma generale del servizio sanitario nazionale dopo la catastrofe pandemica.
Memoria e testimonianza: le stragi del terrorismo in Italia
Authors: Milani Manlio , Vezzadini Susanna
Published: June 2021

L'articolo prende in esame il tema della memoria nelle sue dimensioni privata e pubblica al fine di evidenziare la centralità della testimonianza quale atto pubblico e di impegno civile. In tale prospettiva il contributo si avvale della testimonianza di Manlio Milani, superstite della strage di Piazza della Loggia a Brescia, avvenuta il 28 maggio 1974, nella quale persero la vita la moglie ed alcuni amici. Il valore della testimonianza pubblica è qui affrontato con riguardo ai temi del riconoscimento, della giustizia e del rapporto con la verità.
Il corpo come luogo di testimonianza del passato
Authors: Secco Silvano
Published: June 2021

Questo lavoro cerca di rispondere a due quesiti, il primo riguarda la possibile esistenza di una memoria corporea che precede e prepara le memorie elaborate dal sistema nervoso centrale. Il secondo quesito concerne le modalità attraverso le quali si possono recuperare le memorie corporee. La testimonianza procede dal corpo alla rappresentazione verbale. In tutte le situazioni, normali o traumatiche, sono le immagini a costituire il ponte che collega le memorie del corpo con le memorie della mente. Verrà infine descritta una nuova tecnica che utilizza le immagini del paziente durante il colloquio definita Consulenza psicologica immaginativa.
What Will The Post-Pandemic City Look Like?
Authors: Batty Michael
Published: June 2021

It is impossible to predict the future spatial structure of cities from our current models of location and travel behaviour for the forces that have previously determined where people locate, have been turned on their heads by the pandemic. The only way we can explore such an uncertain future is to build hypothetical cities on which we are able to experiment with different urban futures. Here we build a hypothetical, symmetric, monocentric city which we proceed to lockdown by moving 80 percent of its workers to work from home. We then illustrate how we can relax this situation, letting the city return to a new equilibrium and showing how changes in our travel behaviour can lead to very different forms of future city. We argue that only through hypothetical simulations can we explore this future effectively and we point to where we have applied the model to London.
What are Urban Planning Academics Talking About on Twitter?
Authors: Sanchez Thomas W.
Published: June 2021

The purpose of this analysis is to report on the topics being discussed by urban planning academics on Twitter. Analyzing the content of the tweets helps to understand the topics of conversation and in some sense, the reasons why planning academics use the platform professionally. In many cases the topics identified reflect the research interests of planning academics, while others extend beyond scholarly activities.
Are We Happy in Densely Populated Environments? Assessing the Impacts of Density on Subjective Well-Being, Quality of Life, and Perceived Health in Montreal, Canada.
Authors: Belikow Anastasia , DeWeese James , Ravensbergen Léa , Kestens Yan , El-Geneidy Ahmed
Published: June 2021

Compact city development has been increasingly promoted as a tool to encourage urban sustainability and to reduce humans’ environmental footprint. The impacts of such urban development on subjective well-being (SWB), Quality of Life (QOL), and perceived health—non-monetary metrics of prosperity—have not been extensively explored in the North American context. This paper delves into the relationship between density and happiness by analyzing a travel survey distributed in Montreal, Quebec, Canada (n = 4,148). A cumulative logit model assessed levels of happiness—as measured by SWB, QOL, and perceived health—against confounding variables such as age, gender, household size, marital status, education, income levels, and residential self-selection, while including neighborhood density as our main policy variable. Results do not show that population density affects perceived health or SWB. However, a small inverse relationship between QOL and population density was observed. Analyzing neighborhood characteristics through their effect on SWB, QOL, and perceived health provides further evidence on the links between the urban landscape and happiness, and the study’s results can inform zoning and land-use policymaking.
Airbnb during COVID-19 and what this tells us about Airbnb’s Impact on Rental Prices
Authors: Thackway William Thomas , Pettit Christopher James
Published: June 2021

This study assesses how an overall decline in Airbnb activity due to the COVID-19 pandemic has affected rental supply and prices in Sydney. Using a comprehensive record of Airbnb listings and rental sales data, we study how Airbnb activity and the rental market has changed during the COVID-19 pandemic. We find that in active Airbnb neighbourhoods, the supply of long-term rental stock has increased in response to reduced Airbnb activity, whereas rental supply has fallen in inactive Airbnb neighbourhoods. Our results indicate that rental prices have fallen proportionately with Airbnb activity, up to 7.1% in the most active Airbnb neighbourhoods.
Innovation ecosystems in banking and monetary sector: competitiveness versus sustainability
Authors: Kubus Renata , Mascareñas Pérez-Iñigo Juan , González Fernández Sara
Published: June 2021

This paper addresses the innovation ecosystems configuration of the banking and monetary sector, checking its innovation orientation for competitiveness and sustainability. To achieve this objective, the actors’ perspective from the reframed Innovation Helix is applied. The main result is that the Banking and monetary authorities are rather centred on short-term system stability, which at the longer term can be counterproductive in terms of sustainability. Industry is mainly centred on competitiveness however increasingly taking into account the ‘green transition’. The society, academia and natural environment visions are strongly focused on sustainability. Currency innovations are envisaged at all the levels, bringing different proposals which can be complementary and that bring the potential of more bottom-up initiatives, collaboration and sustainability in socioecological dimension. Metamodern prospect enriches the standpoint.
Data and Business Intelligence Systems for Competitive Advantage: prospects, challenges, and real-world applications
Authors: Djerdjouri Mohamed
Published: June 2021

This paper is intended as a short introduction to Business Intelligence and Analytics systems. The main aim of the paper is to raise awareness of organizations in the developing world, about the benefits of these technologies and the crucial role they play in the survival and competitiveness of the firm in the complex and turbulent global market. For many years, many small and medium-sized businesses (SMBs) have not followed large organizations in the implementation of Business Intelligence technologies. The main reason stated by SMBs is the complexity and high cost of deploying and managing BI systems. However, according to recent IT industry survey of SMBs executives, they now realize the crucial role BI systems play in the company’s performance, and competitiveness and they are now increasingly investing in and implementing Business Intelligence technologies.
Evidenciação contábil nas empresas de capital fechado da região Nordeste do Brasil
Authors: Belarmino Cristiano , Leitão Carla Renata Silva
Published: June 2021

O objetivo deste estudo é identificar como as empresas de capital fechado no nordeste brasileiro têm divulgado seus demonstrativos no Diário Oficial, entre janeiro/março de 2018. O estudo transcorre por meio de pesquisa descritiva e análise de conteúdo. Nos achados, as empresas do Rio Grande do Norte tiveram maior índice de evidenciação. Portanto, os resultados expõem que a evidenciação adotada pelas empresas carece de maior observação das leis e pronunciamentos. Contribuindo no entendimento de como essas empresas evidenciam suas informações, arrazoando concepções que devem ser levadas em consideração como: abrangência e utilidade das demonstrações e falta de homogeneidade das divulgações.
PENGARUH MODEL PERMAINAN FINDING MY SECRET WORD TERHADAP KEMAMPUAN KOMUNIKASI MATEMATIS SISWA
Authors: Farhanah Laila , Arifin Fatkhul
Published: June 2021

The purpose of this study was to determine the effect of using the game finding my secret word on stdents mathematical communication ability. This research was conducted at SD Negeri Jampang 03 class V in the academic year 2019/2020. The research method used was quasi experiment with The Nonequivalent Posttest-Only Group Design. Sample this study amounted to 58 students consisting of 29 experimental class students and 29 control class students. The instrument used in this study was a matter of essay. The data obtained were analyzed by Independent Sample t-Test which produced Sig. (2-tailed) of 0.005 < 0.05, then H0 is rejected and H1 is accepted. This shows that the average value of students mathematical communication ability taught using the game finding my secret word is higher than the average value of students mathematical communication ability taught by conventional learning. Thus, the use of the game finding my secret word has a significant affects on student mathematical communication ability.
Formación integral, inclusión educativa y responsabilidad social
Authors: González Medina Beatriz Alejandra
Published: June 2021

Es relevante para la educación hablar de inclusión y poder ser coherente en todo lo que involucran estas dos palabras en la sociedad. Inclusión es dar la bienvenida a cada ser humano al observarlo, conocerlo y darle la mano a través del acompañamiento en la etapa de desarrollo en que se encuentre; educación es un proceso a lo largo de toda la vida en el cual se forma y se potencia al ser humano en conocimientos, actitudes y habilidades, a través de la motivación o el gusto por aprender y al desaprender para estudiar por medio de la innovación o su propia capacidad. En este artículo se hace mención a una experiencia de cuatro años en los que, con objetividad, se comparten logros al llevar un modelo educativo por competencias en el sistema de preparatoria abierta en un Centro de Atención para Estudiantes con Discapacidad (CAED), ubicado en el CBTis No. 168 de la ciudad de Aguascalientes.
La RIEMS y las tutorías débiles e insuficientes para atender problemas de jóvenes preparatorianos
Authors: Camacho Sandoval Salvador
Published: June 2021

El objetivo del artículo es dar a conocer un conjunto de problemas de diversa índole que presentan los estudiantes de escuelas públicas de educación media superior en Aguascalientes, pero que pueden ser comunes a otras en varios estados del país, mismos que no son fáciles de resolver a través de las tutorías ofrecidas en dichas escuelas. La descripción de esta problemática y el reconocimiento de la incapacidad de atención son producto de la opinión de directivos, tutores y profesores, quienes fueron consultados a través de la aplicación de cuestionarios y entrevistas a profundidad en 2018. Se concluye que, frente a la magnitud de los retos educativos –que también son familiares y sociales–, las tutorías deben estar acompañadas de un trabajo de colaboración directo y eficaz por parte de maestros y padres de familia, así como de personas responsables de instrumentar programas sociales a favor de los jóvenes fuera de la escuela.
Paediatric Life Support by Advanced Paediatric Life Support, Australia: Course Review
Authors: Macfarlane Shannon , Pearce James
Published: June 2021

The Advanced Paediatric Life Support, Australia Paediatric Life Support course is designed to improve outcomes for critically ill and injured paediatrics treated by healthcare professionals. It is comprised of pre-reading, online learning and a one-day face-to-face session that covers basic life support, airway management, cardiac rhythm recognition and defibrillation, intraosseous access and recognition of the seriously injured and ill child. This paper reviews the course and concludes that it should be considered as part of the continuing professional development requirements for paramedics.
Variations in Erosion Risk in Western Anatolia (Turkey): Modified Fournier Approach
Authors: YEŞİLIRMAK Ercan , ATATANIR Levent
Published: June 2021

As a result of global warming, more intense rainfall events and hence higher flood and erosion risk are expected to occur more likely. As erosion has been an important environmental problem in Turkey, it would be beneficial to document how it changed during global warming era. The aim of this study is to investigate the temporal evoluation of erosion risk from 1950 to 2018 in western Anatolia (Turkey), by using Modified Fournier Index (MFI). Also, temporal patterns of annual average temperature and annual total rainfall were analysed. The results, firstly, showed that the study area has cooled slightly from 1950 to 1976 and strongly warmed afterwards, which is consistent with the temporal pattern of global average temperature. Neither annual total rainfall nor MFI showed statistically significant tendencies during both periods. Erosion risk during the rapid warming period was not different from that in the cooling period. It follows that, on the contrary to the expectation, erosion risk in the study area stayed unchaged while average temperature increased substantially after mid-1970s.
Helleborus sp. an ethnopharmacological and toxicological review
Authors: Brajanovska Andzela , Bauer Biljana
Published: June 2021

Helleborus sp. are healing plants from the family Ranunculaceae. The aim of this paper is to consider ethnopharmacology and the toxicity of the hellebores which is focused on a detailed research of the value of phytochemicals, as pharmacological attributes of phytomedicine herbs. The data is based on active components. Also, this paper presents the chemical composition of the root in the overall effect of the drug, as well as the importance of the hellebores in pharmacy. It shows a wide range of pharmacological effects such as cardiotonic, immunostimulative, antibacterial, antitumor, diuretic, and emetic. Helleborus odorus Waldst. et Kit. is rich with secondary metabolites such as bufadenolides, flavonoids, phenolic heterozids. With this research it was concluded that these plants have great significance and great application in the formulation of pharmaceutical dosage forms.

Keywords: Helleborus sp., phytomedicine, folk medicinal uses, cardiotonic, toxicity, hellebore
Chemometrically assisted optimization, development and validation of UPLC method for the analysis of simvastatin
Authors: Hadzieva Gigovska Maja , Petkovska Ana , Manchevska Blagica , Acevska Jelena , Nakov Natalija , Antovska Packa , Ugarkovic Sonja , Dimitrovska Aneta
Published: June 2021

This manuscript presents chemometrically assisted optimization and validation of UPLC method intended for the quantitative analysis of simvastatin in pharmaceutical preparations. To achieve the desired chromatographic response and to simultaneously optimize the most important chromatographic parameters with a limited number of experiments in a minimum amount of time, Box-Behnken design was used. The separation was performed on Poroshell 120 EC C18 50 x 3.0 mm 2.7 μm, using 10 mM ammonium formate pH 4.0 and acetonitrile as the mobile phase. To obtain complete information about method performance and robustness, seven factors (column type, acetonitrile content, temperature, pH of mobile phase, molarities of ammonium formate, flow rate and wavelength) were assessed in twelve experiments according to Plackett–Burman design. The proposed method was validated according to International Conference on Harmonization (ICH) guidelines to confirm specificity, linearity, precision, detection and quantification limits. Validation results have shown that the proposed method is selective, linear, accurate, sensitive (LOD 0.06 μg/mL and LOQ 0.18 μg/mL), and robust and it is suitable for quantitative determination of simvastatin in pharmaceutical preparations. The optimized and validated method gives rapid and efficient separation and represents an improvement over the existing methods especially in the terms of sensitivity, low cost of analysis per sample and the environmental impact of the method. Keywords: chemometry, design of experiments, UPLC/DAD, simvastatin
Stability Analysis of a Mathematical Model SI$_{u}$I$_{a}$QR for COVID-19 with the Effect of Contamination Control (Filiation) Strategy
Authors: ÇAKAN Ümit
Published: June 2021

In this study, using a system of delay nonlinear ordinary differential equations, we introduce a new compartmental epidemic model considered the effect of filiation (contamination) control strategy to the spread of Covid-19. Firstly, the formulation of this new $SI_{u}I_{a}QR$ epidemic model with delay process and the parameters arised from isolation and filiation is formed. Then the disease-free and endemic equilibrium points of the model is obtained. Also, the basic reproduction number $\mathcal{R}_{0}$ is found by using the next-generation matrix method, and the results on stabilities of the disease-free and endemic equilibrium points are investigated. Finally some examples are presented to show the effect of filiation control strategy.
LİSE ÖĞRENCİLERİNİN HÜCRE VE ORGANELLERİ KONUSUNDAKİ TEMEL KAVRAMLARA YÖNELİK BİLGİ DÜZEYLERİNİN BELİRLENMESİ
Authors: GÜL Şeyda , ÖZAY KÖSE Esra
Published: June 2021

Bu çalışma biyolojinin önemli bir konusu olan hücrenin yapısı ve organellerinin öğrenciler tarafından ne düzeyde bilindiğini ortaya çıkarmak amacıyla yürütülmüştür. Çalışma grubunu Erzurum il merkezinde kolay ulaşılabilir örneklem yönteme ile belirlenmiş bir lisenin 9. sınıfında öğrenim gören 35 öğrenci oluşturmaktadır. Nitel araştırma yöntemi ile yürütülen çalışmada öğrencilere hücre ve organellerinin yapısını çizmeleri ve her bir yapının görevini yazmaları istenmiştir. Öğrenci çizimleri ve açıklamalarından elde edilen veriler için betimsel analiz yapılarak frekans ve % değerleri hesaplanmıştır. Elde edilen bulgulara göre öğrencilerin birçoğunun hücre ve organellerinin yapılarını çizmekle beraber, çizimlerin büyük birçoğunun hatalı veya eksik olduğunu göstermiştir. Diğer taraftan ilgili yapıların görevine yönelik sorulan açık uçlu sorulara verilen cevapların çizimlere göre daha fazla doğru bilgiyi içerdiği sonucuna ulaşılmış, bu durum genel olarak öğretim ortamında sunulan bilgilerin ezbere öğretimden uzak, daha somut öğrenmelere odaklı yürütülmesinin, ayrıca ders kitaplarında doğru bilgi ve görsel öğelere daha fazla ağırlık verilmesinin önemli olduğu şeklinde yorumlanmıştır. Çalışmanın sonunda ise ileriye dönük araştırmalar için çalışmanın bulgularına odaklı önerilerde bulunulmuştur.
ORTAÖĞRETİM ÖĞRETMENLERİNİN EĞİTİMDE TEKNOLOJİ KULLANIMINA YÖNELİK GÖRÜŞLERİ DOĞRULTUSUNDA TEKNOLOJİ ENTEGRASYON DÜZEYLERİNİN BELİRLENMESİ
Authors: ARDIÇ Mehmet Alper
Published: June 2021

Ortaöğretim öğretmenlerinin eğitimde teknoloji kullanımına yönelik görüşlerinin ve bu doğrultuda teknoloji entegrasyon düzeylerinin belirlenmeye çalışıldığı araştırmada çeşitli branşlardan 378 öğretmen katılımcı olarak yer almıştır. Nitel araştırma yöntemlerinden durum çalışması modelinin kullanıldığı araştırmada, veri toplama aracı olarak yazılı görüş formundan yararlanılmıştır. Verilerin analizinde betimsel ve içerik analizi yöntemleri kullanılmıştır. Araştırmada öğretmenlerin azımsanmayacak bir kısmının teknoloji kullanımını zaman alıcı, alanlarına uygun olmayan, faydasız faaliyetler olarak görmelerinden dolayı derslerinde teknoloji entegrasyonunu gerçekleştirmedikleri anlaşılmıştır. Öğretmenlerin çoğunluğunun teknolojik araçları ders notlarını yansıtmak, video izlemek ve alıştırma çözmek için kullandıkları görülmüştür. Bu durum, öğretmenlerin derslerde çoğunlukla sadece kendilerinin etkileşime girebileceği donanım/yazılım kullanımına yönelik tercihleriyle birlikte değerlendirildiğinde, genellikle öğretmen merkezli sınıf organizasyonları gerçekleştirdikleri anlaşılmıştır. Ayrıca öğretmenlerin çoğunluğunun öğrencilerin derslerde teknolojik araçlardan yararlanmasına olumsuz baktıkları veya kararsız kaldıkları anlaşılmıştır. Öğretmenlerin önemli bir kısmının teknoloji kullanımına yönelik eğitim almadığı, eğitim alanların çoğunluğunun ise branşlarının öğretimine yönelik özel bir eğitim almadığı görülmüştür. Öğretmenlerin temel yazılım ve donanımları kullanmada sorun yaşamadıkları fakat bunun sadece “yer değiştirme” düzeyinde bir entegrasyon sağladığı anlaşılmıştır. Ayrıca öğretmenlerin alanlarına özgü çeşitli yazılımları kullandıklarında derslerinde “yükseltme” düzeyinde bir kolaylaştırma sağladıkları fakat öğrencilerini aktif olarak sürece dahil edemedikleri görülmüştür. Öte yandan öğretmenlerin derslerinde uygun pedagojik yaklaşımlarla öğrencilerinin de teknolojik araçlarla etkileşime girmelerini sağladıklarında “dönüştürme” düzeyinde bir entegrasyon gerçekleştirdikleri anlaşılmıştır.
Impacto dos agrotóxicos na alimentação: Uma revisão de literatura
Authors: Noblat Ana Karoline de Miranda , Melo Evaneide Maria da Silva , Silva Wilson Antonio da , Silvério Michelline Lins , Correia Juliana Mendes
Published: June 2021

O Brasil é o maior consumidor de agrotóxicos do mundo. A utilização desses pesticidas altera a composição da flora e da fauna, preservando os alimentos dos efeitos nocivos de alguns seres vivos. Porém, seu uso indiscriminado pode gerar danos à saúde humana e ao meio ambiente. O objetivo do presente estudo foi analisar os riscos causados ao homem pelo consumo de alimentos com resíduos de agrotóxicos. Trata-se de uma revisão de literatura do tipo integrativa, com buscas eletrônicas nas bases de dados Scielo (Scientific Electronic Library Online) e Biblioteca Virtual de artigos originais publicados nos últimos oito anos. Em relação aos agrotóxicos, o estudo verificou que, além da diversidade dos utilizados na produção de alimentos, muitos são manuseados de forma incorreta e em quantidades acima das permitidas. Os resíduos desses compostos são encontrados em diversos alimentos de origem vegetal presentes na mesa da maioria da população brasileira e podem causar efeitos nocivos, agudos ou crônicos, a depender do tipo de agrotóxico e do tempo de exposição ao mesmo. Diversas são as ações usadas para minimizar os efeitos dos agrotóxicos, como uma maior fiscalização na comercialização e no manuseio e o estímulo ao consumo de produtos orgânicos provenientes da agricultura familiar.
Sobrecarga de trabalho em enfermagem através do Nursing Activities Score como ferramenta avaliadora
Authors: Martins Victor Hugo da Silva , Nascimento Fernanda Ribeiro , Bezerra Nadyr Cristina , Guisande Tatiana Carla Carvalho Amorim , Tavares Venâncio de Sant'ana , Alencar Angely Anny de Castro , Souza Anna Paula Lima de , Belfort Lucas Rafael Monteiro , Carvalho Marília Andrada Brito
Published: June 2021

O presente estudo buscou identificar o uso do Nursing Activities Score (NAS) para avaliar a sobrecarga de trabalho de enfermagem em estudos nacionais em enfermagem. Trata-se de uma revisão integrativa da literatura, composta de: escolha do tema, levantamento bibliográfico, formulação da pergunta norteadora, busca dos artigos, leitura e redação final do trabalho. A busca dos artigos foi realizada por consulta às bases de dados da BVS (Biblioteca Virtual em Saúde) entre os anos de 2009 e 2019, utilizadas as fontes de dados como LILACS, BDENF, Medline e Scielo. Foram selecionados 16 artigos, os quais levantaram diversos fatores a serem ponderados ao tratar-se de carga de trabalho para enfermagem como conhecimento, técnica, destreza, perfil de liderança, dimensionamento de pessoal, sítios assistenciais, e outros que implicam diretamente na qualidade assistencial. Muitos estudos confirmam o NAS como ferramenta gerencial, mas ainda se vê a pouca utilização do mesmo. É preciso promover a utilização do instrumento para além dos serviços de UTI no país, na visão de melhorar o trabalho, principalmente, dos profissionais de enfermagem, e prestar uma melhor gestão do cuidado para os pacientes.
Are Agatha, Dashiell, and Arthur alive? Assessing the link between hand movements and false intentions
Authors: Baêna Tomás Sanches
Published: June 2021

Background: With the ever-increasing political, ideological and social tension which followed 9/11, crime prevention stands as an issue of major relevance. The development of the ability to accurately detect statements of false intent is of great societal and legal value. It could aid intelligence services in preventing crimes (e.g., terrorist threats) and security services in reinforcing their protocols (e.g., airport security checks, parole hearings, and border control).Goals: To examine the associations between hand movements and false intentions in adults.Methods: Using a laboratory-based variation of the ‘Portsmouth design’, 23 students completed a questionnaire about their intentions to travel in the near future. Participants with a planned trip were placed in the truth tellers’ condition (n = 12). Those who did not have a planned trip were placed in the liars’ condition (n = 11). Based on the main theoretical approaches, three hypotheses were proposed. Hypothesis 1 advocated a decrease in the three categories of illustrators (movements interconnected to speech that serve to illustrate what is being verbally said) in liars, as compared to the truth tellers. Hypothesis 2 also suggested a decrease in the category of subtle hand and finger movements in the lying condition, comparatively with the truth condition. Finally, hypothesis 3 proposed a lack of significant differences between liars and truth-tellers in the five categories of self-adaptors (movements in which one part of the body does something to another body part, such as scratching the ear or squeezing the hands).Results: Hypothesis 1 was partially supported. The general and the unilateral categories of illustrators decreased in the case of the liars, as compared to the truth tellers; however, the bilateral category of illustrators slightly increased in the lying condition, in comparison with truth telling. Hypotheses 2 and 3 were fully supported. Discussion: Apart from the slight increase of bilateral illustrators in the case of the liars, all the results are in accordance with the empirical findings on deception research about past events. This similarity is noteworthy, considering the cognitive differences between lies about past events and lies about future events.
Sympatry and resource partitioning between the largest krill consumers around the Antarctic Peninsula
Authors: Friedlaender AS , Joyce T , Johnston DW , Read AJ , Nowacek DP , Goldbogen JA , Gales N , Durban JW
Published: June 2021

Understanding how closely related, sympatric species distribute themselves relative to their environment is critical to understanding ecosystem structure and function and predicting effects of environmental variation. The Antarctic Peninsula supports high densities of krill and krill consumers; however, the region is warming rapidly, with unknown consequences. Humpback whales Megaptera novaeangliae and Antarctic minke whales Balaenoptera bonaerensis are the largest krill consumers here, yet key data gaps remain about their distribution, behavior, and interactions and how these will be impacted by changing conditions. Using satellite telemetry and novel spatial point-process modeling techniques, we quantified habitat use of each species relative to dynamic environmental variables and determined overlap in core habitat areas during summer months when sea ice is at a minimum. We found that humpback whales ranged broadly over continental shelf waters, utilizing nearshore bays, while minke whales restricted their movements to sheltered bays and areas where ice is present. This presents a scenario where minke whale core habitat overlaps substantially with the broader home ranges of humpback whales. While there is no indication that prey is limiting in this ecosystem, increased overlap between these species may arise as climate-driven changes that affect the extent, timing, and duration of seasonal sea ice decrease the amount of preferred foraging habitat for minke whales while concurrently increasing it for humpback whales. Our results provide the first quantitative assessment of behaviorally based habitat use and sympatry between these 2 krill consumers and offers insight into the potential effects of a rapidly changing environment on the structure and function of a polar ecosystem.
Promoting Reflexive Thinking and Adaptive Expertise Through Video Capturing to Challenge Postgraduate Primary Student Teachers to Think, Know, Feel and Act Like a Teacher
Authors:   College of Education, Univerity of Otago, Sexton Steven S. , Williamson-Leadley Sandra ,   College of Education, Univerity of Otago
Published: June 2021

This article reports on a study of how a one-year, course-taught, master's level Initial Teacher Education (ITE) programme challenged primary student teachers (n = 4) in developing their sense of self-as-teacher. This study examined how the programme's incorporation of video capturing technology impacted on these student teachers' development of reflexivity and adaptive expertise. Student teachers self-selected a community of practice to include two experienced teachers acting as facilitators. Using a secure video capturing system, student teachers collected samples of teaching practice. Then through student teacher led discussions, they and their community of practice examined how they were developing as teachers. Results indicate how video capturing provided the experiences necessary for these student teachers to reflect on teaching practice and learn how to think, know, feel and act like a teacher. Implications of this research highlight the benefits of student teachers actually seeing their own teaching practice and then using these examples of teaching as evidence of how they were becoming reflexive and adaptive teachers.
Organization of contents in intended junior secondary science curriculum of Bangladesh: An explorative study
Authors:   Lecturer Institute of Education and Research Khulna University, Khulna, Bain Kalyani , Siddique Mohammad Nure Alam ,   Associate Professor Institute of Education and Research University of Dhaka, Dhaka
Published: June 2021

This study explored the organization of contents in the junior secondary science curriculum of Bangladesh. The research questions of this study focus on how science content is sequenced and integrated in the intended curriculum. Document analysis within a qualitative approach has been followed to conduct this study. Both the junior secondary science curriculum and textbooks have been analyzed to address the research questions. This study finds that the current Science curriculum at the junior secondary level is not well-organized in terms of sequencing and integration. No principle of sequencing content is followed in most cases. It is noted that in the case of intergrades vertical sequencing, 'Spiral sequencing' is partially followed in a few cases. This study also finds that the current Science curriculum does not integrate the content adequately. Intra-disciplinary integration, i.e. integrating different sub-disciplines of Science, has been tried but the level of integration is not adequate rather it is very low. This study recommends that curriculum developers make efforts to make the content better organized in both the curriculum and textbooks by following the principles of sequencing and integration.
Strategies for Poly(3-hydroxybutyrate) Production Using a Cold-Shock Promoter in Escherichia coli
Authors: Boontip Thanawat , Waditee-Sirisattha Rungaroon , Honda Kohsuke , Napathorn Suchada Chanprateep
Published: June 2021

The present study attempted to increase poly(3-hydroxybutyrate) (PHB) production by improving expression of PHB biosynthesis operon derived from Cupriavidus necator strain A-04 using various types of promoters. The intact PHB biosynthesis operon of C. necator A-04, an alkaline tolerant strain isolated in Thailand with a high degree of 16S rRNA sequence similarity with C. necator H16, was subcloned into pGEX-6P-1, pColdI, pColdTF, pBAD/Thio-TOPO, and pUC19 (native promoter) and transformed into Escherichia coli JM109. While the phaCA–04 gene was insoluble in most expression systems tested, it became soluble when it was expressed as a fusion protein with trigger factor (TF), a ribosome associated bacterial chaperone, under the control of a cold shock promoter. Careful optimization indicates that the cold-shock cspA promoter enhanced phaCA–04 protein expression and the chaperone function of TF play critical roles in increasing soluble phaCA–04 protein. Induction strategies and parameters in flask experiments were optimized to obtain high expression of soluble PhaCA–04 protein with high YP/S and PHB productivity. Soluble phaCA–04 was purified through immobilized metal affinity chromatography (IMAC). The results demonstrated that the soluble phaCA–04 from pColdTF-phaCABA–04 was expressed at a level of as high as 47.4 ± 2.4% of total protein and pColdTF-phaCABA–04 enhanced soluble protein formation to approximately 3.09−4.1 times higher than that from pColdI-phaCABA–04 by both conventional method and short induction method developed in this study. Cultivation in a 5-L fermenter led to PHB production of 89.8 ± 2.3% PHB content, a YP/S value of 0.38 g PHB/g glucose and a productivity of 0.43 g PHB/(L.h) using pColdTF-phaCABA–04. The PHB film exhibited high optical transparency and possessed Mw 5.79 × 105 Da, Mn 1.86 × 105 Da, and PDI 3.11 with normal melting temperature and mechanical properties.
Oral Delivery of Biologics in Inflammatory Bowel Disease Treatment
Authors: Zhang Wunan , Michalowski Cecilia Bohns , Beloqui Ana
Published: June 2021

Inflammatory bowel disease (IBD) has been posed as a great worldwide health threat. Having an onset during early adulthood, IBD is a chronic inflammatory disease characterized by remission and relapse. Due to its enigmatic etiology, no cure has been developed at the moment. Conventionally, steroids, 5-aminosalicylic acid, and immunosuppressants have been applied clinically to relieve patients’ syndrome which, unfavorably, causes severe adverse drug reactions including diarrhea, anemia, and glaucoma. Insufficient therapeutic effects also loom, and surgical resection is mandatory in half of the patients within 10 years after diagnosis. Biologics demonstrated unique and differentiative therapeutic mechanism which can alleviate the inflammation more effectively. However, their application in IBD has been hindered considering their stability and toxicity. Scientists have brought up with the concept of nanomedicine to achieve the targeted drug delivery of biologics for IBD. Here, we provide an overview of biologics for IBD treatment and we review existing formulation strategies for different biological categories including antibodies, gene therapy, and peptides. This review highlights the current trends in oral delivery of biologics with an emphasis on the important role of nanomedicine in the development of reliable methods for biologic delivery in IBD treatment.
Bioengineering Technologies for Cardiac Regenerative Medicine
Authors: Chingale Mira , Zhu Dashuai , Cheng Ke , Huang Ke
Published: June 2021

Cardiac regenerative medicine faces big challenges such as a lack of adult cardiac stem cells, low turnover of mature cardiomyocytes, and difficulty in therapeutic delivery to the injured heart. The interaction of bioengineering and cardiac regenerative medicine offers innovative solutions to this field. For example, cell reprogramming technology has been applied by both direct and indirect routes to generate patient-specific cardiomyocytes. Various viral and non-viral vectors have been utilized for gene editing to intervene gene expression patterns during the cardiac remodeling process. Cell-derived protein factors, exosomes, and miRNAs have been isolated and delivered through engineered particles to overcome many innate limitations of live cell therapy. Protein decoration, antibody modification, and platelet membranes have been used for targeting and precision medicine. Cardiac patches have been used for transferring therapeutics with better retention and integration. Other technologies such as 3D printing and 3D culture have been used to create replaceable cardiac tissue. In this review, we discuss recent advancements in bioengineering and biotechnologies for cardiac regenerative medicine.