bluuebunny/crossref_metadata_2025 huggingface dataset:
Toxicity Analysis of Mesoporous Polydopamine on Intestinal Tissue and Microflora
Authors: Xie Luoyijun , Li Qiyan , Liao Yingying , Huang Zihua , Liu Yulin , Liu Chutong , Shi Leilei , Li Qingjiao , Yuan Miaomiao
Published: October 2022

As a promising therapy, photothermal therapy (PTT) converts near-infrared (NIR) light into heat through efficient photothermal agents (PTAs), causing a rapid increase in local temperature. Considering the importance of PTAs in the clinical application of PTT, the safety of PTAs should be carefully evaluated before their widespread use. As a promising PTA, mesoporous polydopamine (MPDA) was studied for its clinical applications for tumor photothermal therapy and drug delivery. Given the important role that intestinal microflora plays in health, the impacts of MPDA on the intestine and on intestinal microflora were systematically evaluated in this study. Through biological and animal experiments, it was found that MPDA exhibited excellent biocompatibility, in vitro and in vivo. Moreover, 16S rRNA analysis demonstrated that there was no obvious difference in the composition and classification of intestinal microflora between different drug delivery groups and the control group. The results provided new evidence that MPDA was safe to use in large doses via different drug delivery means, and this lays the foundation for further clinical applications.
Determination of Cyclaniliprole in Fruits and Vegetables Using Disposable Pipette Extraction Cleanup and Ultrahigh-Performance Liquid Chromatography-Tandem Mass Spectrometry
Authors: Lu Zhou , Yue Weiqian , Ren Weiming , Wang Yanhong , Li Yueru
Published: October 2022

Despite an outstanding agent for control of Lepidoptera, the diamide insecticide cyclaniliprole (CYCP) is a suspected carcinogen. In the present study, an analytical method was developed for the determination of CYCP in six fruits and vegetables (apple, grape, peach, bell pepper, lettuce, and tomato) using ultrahigh-performance liquid chromatography coupled with tandem mass spectrometry. Sample preparation was carried out by the acetonitrile-salting-out extraction followed by simple and fast cleanup of disposable pipette extraction tip containing styrene divinyl benzene and/or graphitized carbon black. Satisfactory linearity (r > 0.99) was obtained in the calibration range of 0.001–1 µg mL−1. Matrix effects decreased from −9.9–−17.9% to −1.0–−7.6% after the cleanup. The recoveries of CYCP at three spike levels (0.01, 0.1, and 1 mg kg−1) from different matrices were between 75.7% and 111.5%, with the intra-day (n = 5) and inter-day (n = 15) relative standard deviations lower than 12.1%. The limit of quantification was 0.01 mg kg−1. The developed method provides a good reference for routine monitoring of CYCP in these fruits and vegetables.
Simultaneous Prediction, Determination, and Extraction of Four Polycyclic Aromatic Hydrocarbons in the Environment Using a UCON–NaH2PO4 Aqueous Two-Phase Extraction System Combined with High-Performance Liquid Chromatography-Ultraviolet Detection
Authors: Chang He , Lu Yang , Sun Yantao
Published: October 2022

In this paper, a new aqueous two-phase extraction system(ATPES) consisting of UCON (poly(ethylene glycol-ran-propylene glycol) monobutyl ether)–NaH2PO4 was established, and four trace polycyclic aromatic hydrocarbons (PAHs: fluorene, anthracene, pyrene and phenanthrene) in water and soil were analyzed by high-performance liquid chromatography (HPLC)–ultraviolet detection. In the multi-factor experiment, the central composite design (CCD) was used to determine the optimum technological conditions. The final optimal conditions were as follows: the concentration of UCON was 0.45 g·mL−1, the concentration of NaH2PO4 was 3.5 mol·L−1, and the temperature was 30 °C. The recovery of the four targets was 98.91–99.84% with a relative standard deviation of 0.3–2.1%. Then UCON recycling and cyclic tests were designed in the experiment, and the results showed that the recovery of PAHs gradually increased in the three extractions because of the remaining PAHs in the salt phase of last extraction. The recovery of PAHs in the UCON recycling test was less than that in the extraction test due to the wastage of UCON. In addition, a two-phase aqueous extraction model was established based on the random forest (RF) model. The results obtained were compared with the experimental data, and the root mean square error (RMSE) was 0.0371–0.0514 and the correlation coefficient R2 was 96.20–98.53%, proving that the model is robust and reliable.
Recent Advances in Mass Spectrometry-Based Structural Elucidation Techniques
Authors: Ma Xin
Published: October 2022

Mass spectrometry (MS) has become the central technique that is extensively used for the analysis of molecular structures of unknown compounds in the gas phase. It manipulates the molecules by converting them into ions using various ionization sources. With high-resolution MS, accurate molecular weights (MW) of the intact molecular ions can be measured so that they can be assigned a molecular formula with high confidence. Furthermore, the application of tandem MS has enabled detailed structural characterization by breaking the intact molecular ions and protonated or deprotonated molecules into key fragment ions. This approach is not only used for the structural elucidation of small molecules (MW < 2000 Da), but also crucial biopolymers such as proteins and polypeptides; therefore, MS has been extensively used in multiomics studies for revealing the structures and functions of important biomolecules and their interactions with each other. The high sensitivity of MS has enabled the analysis of low-level analytes in complex matrices. It is also a versatile technique that can be coupled with separation techniques, including chromatography and ion mobility, and many other analytical instruments such as NMR. In this review, we aim to focus on the technical advances of MS-based structural elucidation methods over the past five years, and provide an overview of their applications in complex mixture analysis. We hope this review can be of interest for a wide range of audiences who may not have extensive experience in MS-based techniques.
A Potential Role of Plant/Macrofungi/Algae-Derived Non-Starch Polysaccharide in Colitis Curing: Review of Possible Mechanisms of Action
Authors: Feng Jinxiu , Geng Jingzhang , Wu Jinhui , Wang Huiying , Liu Yanfei , Du Bin , Yang Yuedong , Xiao Haitao
Published: October 2022

Multiple in vitro and in vivo model investigations have suggested a broad spectrum of potential mechanisms by which plant/macrofungi-derived non-starch polysaccharides may play a role in the treatment of inflammatory bowel disease (IBD). This article reviews the in vivo and in vitro evidence of different plant-derived polysaccharides for IBD therapy. Their underlying mechanisms, particularly the molecular mechanisms associated with protective effects in the treatment and prevention of IDB, have been well summarized, including anti-inflammatory, epithelial barrier repair, and the regulation of intestinal flora. Emerging studies have observed the potent role of probiotics in IBD, particularly its ability to modulate gut microbiota, a well-known key factor for IBD. In summary, plant/macrofungi-derived polysaccharides have the potential to be a promising agent for the adjuvant treatment and prevention of IBD and will contribute to the design of well-designed clinical intervention trials that will ultimately improve the therapy of IBD.
Interaction of the Fungal Metabolite Harzianic Acid with Rare-Earth Cations (Pr3+, Eu3+, Ho3+, Tm3+)
Authors: Salvatore Maria Michela , Siciliano Antonietta , Staropoli Alessia , Vinale Francesco , Nicoletti Rosario , DellaGreca Marina , Guida Marco , Salvatore Francesco , Iuliano Mauro , Andolfi Anna , De Tommaso Gaetano
Published: October 2022

Rare-earth elements (REEs) are in all respect a class of new contaminants that may have toxic effects on organisms and microorganisms and information on their interactions with natural ligands should be of value to predict and control their diffusion in natural environments. In the current study, we investigate interactions of tripositive cations of praseodymium, europium, holmium, and thulium with harzianic acid (H2L), a secondary metabolite produced by selected strains of fungi belonging to the Trichoderma genus. We applied the same techniques and workflow previously employed in an analogous study concerning lanthanum, neodymium, samarium, and gadolinium tripositive cations. Therefore, in the current study, HPLC-ESI-HRMS experiments, circular dichroism (CD), and UV-Vis spectrophotometric absorption data, as well as accurate pH measurements, were applied to characterize bonding interactions between harzianic acid and Pr3+, Eu3+, Ho3+, and Tm3+ cations. Problems connected to the low solubility of harzianic acid in water were overcome by employing a 0.1 M NaClO4/(CH3OH + H2O 50/50 w/w) mixed solvent. For Pr3+, Ho3+, and Tm3+, only the mono complexes PrL+, HoL+, and TmL+ were detected and their formation constant determined. Eu3+ forms almost exclusively the bis complex EuL2− for which the corresponding formation constant is reported; under our experimental conditions, the mono complex EuL+ is irrelevant. Combining the results of the present and previous studies, a picture of interactions of harzianic acid with rare-earth cations extending over 8 of the 17 REEs can be composed. In order to complement chemical information with toxicological information, a battery of bioassays was applied to evaluate the effects of praseodymium, europium, holmium, and thulium tripositive cations on a suite of bioindicators including Aliivibrio fischeri (Gram-negative bacterium), Raphidocelis subcapitata (green alga), and Daphnia magna (microcrustacean), and median effective concentration (EC50) values of Pr3+, Eu3+, Ho3+, and Tm3+ for the tested species were assessed.
New Green Approaches in Nanoparticles Synthesis: An Overview
Authors: Miu Bogdan Andrei , Dinischiotu Anca
Published: October 2022

Nanotechnology is constantly expanding, with nanomaterials being more and more used in common commercial products that define our modern life. Among all types of nanomaterials, nanoparticles (NPs) occupy an important place, considering the great amount that is produced nowadays and the diversity of their applications. Conventional techniques applied to synthesize NPs have some issues that impede them from being appreciated as safe for the environment and health. The alternative to these might be the use of living organisms or biological extracts that can be involved in the green approach synthesis of NPs, a process that is free of harmful chemicals, cost-effective and a low energy consumer. Several factors, including biological reducing agent concentration, initial precursor salt concentration, agitation, reaction time, pH, temperature and light, can influence the characteristics of biologically synthesized NPs. The interdependence between these reaction parameters was not explored, being the main impediment in the implementation of the biological method on an industrial scale. Our aim is to present a brief review that focuses on the current knowledge regarding how the aforementioned factors can control the size and shape of green-synthesized NPs. We also provide an overview of the biomolecules that were found to be suitable for NP synthesis. This work is meant to be a support for researchers who intend to develop new green approaches for the synthesis of NPs.
Molecular and Structural Analysis of Specific Mutations from Saudi Isolates of SARS-CoV-2 RNA-Dependent RNA Polymerase and their Implications on Protein Structure and Drug–Protein Binding
Authors: Alamri Mubarak A. , Tahir ul Qamar Muhammad , Alabbas Alhumaidi B. , Alqahtani Safar M. , Alossaimi Manal A. , Azam Sikandar , Hashmi Muhammad Harris , Rajoka Muhammad Shahid Riaz
Published: October 2022

The COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has stressed the global health system to a significant level, which has not only resulted in high morbidity and mortality but also poses a threat for future pandemics. This situation warrants efforts to develop novel therapeutics to manage SARS-CoV-2 in specific and other emerging viruses in general. This study focuses on SARS-CoV2 RNA-dependent RNA polymerase (RdRp) mutations collected from Saudi Arabia and their impact on protein structure and function. The Saudi SARS-CoV-2 RdRp sequences were compared with the reference Wuhan, China RdRp using a variety of computational and biophysics-based approaches. The results revealed that three mutations—A97V, P323I and Y606C—may affect protein stability, and hence the relationship of protein structure to function. The apo wild RdRp is more dynamically stable with compact secondary structure elements compared to the mutants. Further, the wild type showed stable conformational dynamics and interaction network to remdesivir. The net binding energy of wild-type RdRp with remdesivir is -50.76 kcal/mol, which is more stable than the mutants. The findings of the current study might deliver useful information regarding therapeutic development against the mutant RdRp, which may further furnish our understanding of SARS-CoV-2 biology.
Transcriptome and Metabolome Analyses Provide Insights into the Flavonoid Accumulation in Peels of Citrus reticulata ‘Chachi’
Authors: Su Jianmu , Peng Tianhua , Bai Mei , Bai Haiyi , Li Huisi , Pan Huimin , He Hanjun , Liu Huan , Wu Hong
Published: October 2022

The quality of Chinese medicinal materials depends on the content of bioactive components, which are affected by the environmental factors of different planting regions. In this research, integrated analysis of the transcriptome and metabolome of C. reticulata ‘Chachi’ was performed in two regions, and three orchards were included in the analysis. In total, only 192 compounds were found in fresh peels, and among 18 differentially accumulated flavonoid metabolites, 15 flavonoids were enriched in peels from the Xinhui planting region. In total, 1228 genes were up-regulated in peels from Xinhui, including the CHS and GST genes, which are involved in the salt stress response. Overall, based on the correlation analysis of flavonoid content and gene expression in peels of C. reticulata ‘Chachi’, we concluded that the authenticity of the GCRP from Xinhui may be closely related to the higher content of naringin and narirutin, and the increase in the content of these may be due to the highly saline environment of the Xinhui region.
Essential Oil Composition and Traditional Uses of Salvia dentata, a Poorly Known Medicinal Plant from Namaqualand, South Africa
Authors: Rattray Ryan D. , Mokwena Lucky , Stander Marietjie A. , Van Wyk Ben-Erik
Published: October 2022

South Africa has a rich history of medicinal plant species and their documented uses as traditional medicines, and is also home to three well-known, blue-flowered sage species of ethnobotanical importance. The Namaqualand bloublomsalie (Salvia dentata) has so far remained unstudied and apparently overlooked. Our study is the first to report on the essential oil chemistry of this medicinally relevant species and provide a comparison with the other two (well-studied) closely related Cape bloublomsalies (Salvia africana and S. chamelaeagnea). The data, generated from three geographically isolated populations comprised of 13 individual plants of S. dentata, revealed diagnostically high levels of camphor (14.37%), α-pinene (11.43%), camphene (10.18%), 1,8-cineole (eucalyptol) (9.42%) and bornyl acetate (8.56%) which provide a distinct chemical profile from the other two species.
A Highly Efficient Biomass Compound Aerosol Suppressant in Purifying Radioactive Cesium Droplet Aerosols
Authors: Wu Lang , Lei Shuchang , Wang Yixia , Yang Shiyu , Lin Xiaoyan , Wang Haijun
Published: October 2022

Nuclear accidents and decommissioning in the nuclear industry would release a large number of radioactive aerosols which endangers the natural environment and the health of workers. Therefore, there is an urgent need for environment-friendly aerosol suppressants to control and handle environmental pollution problems caused by radioactive aerosols. In this paper, sodium alginate (SA), a type of polyphenol material (TP), and alkyl glycosides (APGs) were selected as the components of the compound aerosol suppressant and the optimal proportion was generated via the method of D-optimal mixture design. Furthermore, the cesium aerosol sedimentation effect of the optimized compound aerosol suppressants was evaluated via sedimentation efficiency, the change in particle concentration cumulative concentration fraction of the cesium aerosol sedimentation process. The results showed that the aerosol sedimentation efficiency was 99.82% which was much higher than nature settlement, 18.6% and water spraying sedimentation, 43.3%. Moreover, after spraying the compound suppressant, it displayed a good effect on settling the cesium aerosol particles with a diameter of less than 1 µm, as the concentration of particles was reduced from 55.49% to 44.53%. Finally, the sedimentation mechanism of the compound aerosol suppressant and cesium aerosol particles, such as the coagulation effect, was analyzed using the particle size distribution.
Structural Diversity and Carbon Dioxide Sorption Selectivity of Zinc(II) Metal-Organic Frameworks Based on Bis(1,2,4-triazol-1-yl)methane and Terephthalic Acid
Authors: Sukhikh Taisiya S. , Filatov Evgeny Yu. , Ryadun Alexey A. , Kovalenko Konstantin A. , Potapov Andrei S.
Published: October 2022

A three-component reaction between the 1,4-benzenedicarboxylic (terephthalic) acid (H2bdc), bis(1,2,4-triazol-1-yl)methane (btrm) and zinc nitrate was studied, and three new coordination polymers were isolated by a careful selection of the reaction conditions. Coordination polymers {[Zn3(DMF)(btrm)(bdc)3]·nDMF}∞ and {[Zn3(btrm)(bdc)3]·nDMF}∞ containing trinuclear {Zn3(bdc)3} secondary building units are joined by btrm auxiliary linkers into three-dimensional metal–organic frameworks. The coordination polymer {[Zn(bdc)(btrm)]∙nDMF}∞ consists of Zn2+ cations joined by bdc2− and btrm linkers into a two-fold interpenetrated network. Upon activation, MOF [Zn3(btrm)(bdc)3]∞ demonstrated CO2/N2 adsorption selectivity with an ideal adsorbed solution theory (IAST) factor of 21. All three MOF demonstrated photoluminescence with a maximum near 435–440 nm upon excitation at 330 nm.
H-Bonding Room Temperature Phosphorescence Materials via Facile Preparation for Water-Stimulated Photoluminescent Ink
Authors: Lou Lingyun , Xu Tianqi , Li Yuzhan , Zhang Changli , Wang Bochun , Zhang Xusheng , Zhang Hean , Qiu Yuting , Yang Junyan , Wang Dong , Cao Hui , He Wanli , Yang Zhou
Published: October 2022

Pure organic room-temperature phosphorescence (RTP) materials built upon noncovalent interactions have attracted much attention because of their high efficiency, long lifetime, and stimulus-responsive behavior. However, there are limited reports of noncovalent RTP materials because of the lack of specific design principles and clear mechanisms. Here, we report on a noncovalent material prepared via facile grinding that can emit fluorescence and RTP emission differing from their components’ photoluminescent behavior. Exciplex can be formed during the preparation process to act as the minimum emission unit. We found that H-bonds in the RTP system provide restriction to nonradiative transition but also enhance energy transformation and energy level degeneracy in the system. Moreover, water-stimulated photoluminescent ink is produced from the materials to achieve double-encryption application with good resolution.
Multivariate Statistical Analysis for Mutual Dependence Assessment of Selected Polyphenols, Organic Acids and Metals in Cool-Climate Wines
Authors: Fabjanowicz Magdalena , Simeonov Vasil , Frankowski Marcin , Wojnowski Wojciech , Płotka-Wasylka Justyna
Published: October 2022

Polyphenols, organic acids and metal ions are an important group of compounds that affect the human health and quality of food and beverage products, including wines. It is known that a specific correlation between these groups exist. While wines coming from the New World and the Old World countries are extensively studied, wines coming from cool-climate countries are rarely discussed in the literature. One of the goals of this study was to determine the elemental composition of the wine samples, which later on, together as polyphenols and organic acids content, was used as input data for chemometric analysis. The multivariate statistical approach was applied in order to find specific correlations between the selected group of compounds in the cool-climate wines and the features that distinguish the most and differ between red and white wines and rosé wines. Moreover, special attention was paid to resveratrol and its correlation with selected wine constituents.
Electronic Structure-, Phonon Spectrum-, and Effective Mass- Related Thermoelectric Properties of PdXSn (X = Zr, Hf) Half Heuslers
Authors: Rani Bindu , Wani Aadil Fayaz , Sharopov Utkir Bahodirovich , Patra Lokanath , Singh Jaspal , Ali Atif Mossad , Abd El-Rehim A. F. , Khandy Shakeel Ahmad , Dhiman Shobhna , Kaur Kulwinder
Published: October 2022

We hereby discuss the thermoelectric properties of PdXSn(X = Zr, Hf) half Heuslers in relation to lattice thermal conductivity probed under effective mass (hole/electrons) calculations and deformation potential theory. In addition, we report the structural, electronic, mechanical, and lattice dynamics of these materials as well. Both alloys are indirect band gap semiconductors with a gap of 0.91 eV and 0.82 eV for PdZrSn and PdHfSn, respectively. Both half Heusler materials are mechanically and dynamically stable. The effective mass of electrons/holes is (0.13/1.23) for Zr-type and (0.12/1.12) for Hf-kind alloys, which is inversely proportional to the relaxation time and directly decides the electrical/thermal conductivity of these materials. At 300K, the magnitude of lattice thermal conductivity observed for PdZrSn is 15.16 W/mK and 9.53 W/mK for PdHfSn. The highest observed ZT value for PdZrSn and PdHfSn is 0.32 and 0.4, respectively.
Regioselective Synthesis of 5-Trifluoromethyl 1,2,4-Triazoles via [3 + 2]-Cycloaddition of Nitrile Imines with CF3CN
Authors: Lin Bo , Zhang Zipeng , Yao Yunfei , You Yi , Weng Zhiqiang
Published: October 2022

We herein describe a general approach to 5-trifluoromethyl 1,2,4-triazoles via the [3 + 2]-cycloaddition of nitrile imines generated in situ from hydrazonyl chloride with CF3CN, utilizing 2,2,2-trifluoroacetaldehyde O-(aryl)oxime as the precursor of trifluoroacetonitrile. Various functional groups, including alkyl-substituted hydrazonyl chloride, were tolerated during cycloaddition. Furthermore, the gram-scale synthesis and common downstream transformations proved the potential synthetic relevance of this developed methodology.
Moco Carrier and Binding Proteins
Authors: Kruse Tobias
Published: October 2022

The molybdenum cofactor (Moco) is the active site prosthetic group found in numerous vitally important enzymes (Mo-enzymes), which predominantly catalyze 2 electron transfer reactions. Moco is synthesized by an evolutionary old and highly conserved multi-step pathway, whereby the metal insertion reaction is the ultimate reaction step here. Moco and its intermediates are highly sensitive towards oxidative damage and considering this, they are believed to be permanently protein bound during synthesis and also after Moco maturation. In plants, a cellular Moco transfer and storage system was identified, which comprises proteins that are capable of Moco binding and release but do not possess a Moco-dependent enzymatic activity. The first protein described that exhibited these properties was the Moco carrier protein (MCP) from the green alga Chlamydomonas reinhardtii. However, MCPs and similar proteins have meanwhile been described in various plant species. This review will summarize the current knowledge of the cellular Moco distribution system.
The role of volunteering in the state social policy implementation (on the example of the city of Magnitogorsk)
Authors:   FSBEI HE Nosov Magnitogorsk State Technical University, Bezenkova T. A. , Ilyasov I. R. ,   FSBEI HE Nosov Magnitogorsk State Technical University
Published: October 2022

Currently, volunteering plays a significant role in the implementation of the state social policy. On the one hand, the number of volunteers is growing, but, on the other hand, there are many questions and problems regarding the participation of people in volunteer activities. In order to study the attitude of young people to volunteering, their motives, and willingness to participate, a survey among 1st year university students majoring in Social Work was conducted. The choice of respondents was not random: their future profession of a social work specialist is directly related to the state social policy implementation. It was found that most of all young people are attracted to volunteering by a noble idea, the possibility of gaining new experience, self-realization, and new opportunities and hobbies. Thus, young people often begin to volunteer in order to satisfy their needs and interests in the first place. A novice volunteer can form humanistic values and the need to help people while being in the community united by the idea of helping others. An example is the activities of the all-Russian social movement "Volunteers of Victory", in particular, its branch in the city of Magnitogorsk. "Volunteers of Victory" cooperate with the city social service institutions, helping to solve various social problems, organize events for the patriotic education of children and youth, and conduct educational work, thereby contributing to the creation of a socio-cultural environment aimed at educating a socially active person and to the solution of topical social issues.
Implementation of social partnership technology in the prevention of family disadvantages
Authors:   FSBEI HE Nosov Magnitogorsk State Technical University, Oleynik E. V.
Published: October 2022

Currently, there are different types of dysfunctional families: conflictual, immoral, pedagogically untenable, asocial. The causes of family disadvantages may be crisis phenomena in the socio-economic sphere, disorder of intra-family relations between parents and children, physically or mentally ill parents, unfavorable heredity in children, or presence of children or adults with disabilities in the family. Prevention of family disadvantages implies a set of measures to work with parents and children in order to form and maintain normal family relations, focus on a healthy lifestyle, and revive the institution of family and marriage. There are various ways to organize effective work in this direction, but the most effective is the implementation of social partnership technology. Such a partnership can be implemented through the interaction of various social institutions, such as social protection management bodies and social protection institutions, education management bodies and educational institutions, commissions for minors and for protection of their rights, special institutions for minors in need of social rehabilitation, guardianship and custody authorities, health management bodies and health care institutions, internal affairs bodies, bodies, institutions, and public associations, implementing measures to prevent neglect and juvenile delinquency, etc. Within the framework of social partnership technology, specialists of these institutions can ensure the prevention of family disadvantages more successfully and effectively by creating a unified concept of joint actions in relation to a particular family. Also, the implementation of social partnership technology will allow for the exchange of information characterizing the situation of families and children in the subordinate territory that is necessary for carrying out activities in their interests with authorities, state and non-governmental institutions, organizations and services.
Digitizing cadastral maps in the Syrian Arab Republic using the ArcGIS software
Authors:   Moscow State University of Geodesy and Cartography, Moscow, Grigoriev S. A. , Mohammad B. A. ,   Moscow State University of Geodesy and Cartography, Moscow
Published: October 2022

Under conditions of prolonged daylight cotton forms a powerful vegetative mass. This slows down the ripening of the pods, which is a signifi cant prerequisite for the use of honey bees in the pollination of this crop. During the season in the cotton-growing zone in the Republic of Uzbekistan bees are transported from six to ten times in special pavilions from one fi eld to another. At the same time cross–pollination increases the yield of cotton crops by two to three times. Cotton honey has a number of distinctive characteristics associated with the presence of essential oil, which gives it special biochemical properties. In 100 g of cotton honey carbohydrates account for up to 80,0 %, less than 1,0 % of proteins in the complete absence of fats. Despite this biochemical composition cotton honey crystallizes. The purpose of the research was to study the interior indicators of the organism of bees during the wintering of bee nucleus on cotton, fl ower and sugar honey under the conditions of the Republic of Uzbekistan. Experiments have been carried out on fi ve varieties of honey used for wintering of bees including cotton honey. It has been shown that the highest levels of interior indicators at the beginning and end of wintering were recorded when using fl ower honey (the 1st control group), both with the option of forming nucleus in 2 spaces between honeycombs, and in particular in 3 spaces between honeycombs. Here, the preservation of the reserve substances of the fat body in bees was 3,15 points in 2 spaces between honeycombs, and 3,50 points in 3 spaces between honeycombs, compared with the beginning of wintering the decrease was 21,25 and 12,50 %. At the same time the safety of nitrogen, fat and dry matter in the body of working bees of the described group was also high. In the variants with cotton honey (the 2nd experimental group) the decrease was 3,27 and 3,29 times in nitrogen, 1,93 and 1,9 times in fat, 2,22 and 2,12 times in dry matter, respectively. Despite the fact that sugar honey is poor in chemical elements needed by the body of worker bees, it does not crystallize, and its carbohydrates performing an energetic and plastic function, save bees from starvation during the critical period of wintering.
Results of Semigroup of Linear Equation Generating a Wave Equation
Authors: Omosowon J. B. , Akinyele A. Y. , Saka-Balogun O. Y.
Published: October 2022

In this paper, we present results of $\omega$-order preserving partial contraction mapping generating a wave equation. We use the theory of semigroup to generate a wave equation by showing that the operator $ \begin{pmatrix} 0 & I\\ \Delta & 0 \end{pmatrix}, $ which is $A,$ is the infinitesimal generator of a $C_0$-semigroup of operators in some appropriately chosen Banach of functions. Furthermore we show that the operator $A$ is closed, unique and that operator $A$ is the infinitesimal generator of a wave equation.
Anxiety Levels In Menopausal Women
Authors: Ima Sukmawati  , Rahayu Yuyun , Noviati Elis
Published: October 2022

Background: Menopausal women experience physiological and psychological changes. The effects of these symptoms are headaches, hair loss, muscle pain, vaginal dryness, insomnia, weight gain, anxiety, irritability, difficulty concentrating, nervousness, feeling worthless, stress, and even depression. Objective: to determine the level of anxiety about menopause in Benteng Ciamis Village. Methods: The study used a descriptive method by filling out a questionnaire. Results: It was found that of the 30 respondents in the category of severe anxiety, 23 respondents (76.7%). Economic factors, knowledge and lack of recreation are the biggest contributing factors to anxiety in mothers facing menopause. Suggestion: support is needed, especially from the husband so that the anxiety experienced by the mother can be overcome.

Keywords: Anxiety level, Menopausal  women
Farsas e impertinencias en los estudios de las literaturas originarias
Authors: Velásquez-Garambel José Luis , Sucari Wilson
Published: October 2022

Luego de examinar los trabajos sobre literatura oral altiplánica, encontramos pocos registros en las lenguas originales, la mayoría de las veces se recurrió a recopilar versiones en lengua castellana, en su variedad andina, diglósica; ejercicio en el que se ha dejado de lado el universo metafórico y simbólico, propio de cada lengua y variedad, desnaturalizando el significado cultural asignado por la convención de su contexto. Así se publicaron textos “de la literatura quechua o aymara” con perspectivas hispánicas, reforzados con traducciones descontextualizadas y que terminaron rompiendo el hilo semántico que caracteriza la ironía, el humor y las metáforas que, en su oralidad, aún contienen las literaturas originales, para el caso de Puno, quechua - aymara.
Las lógicas fronterizas de Gamaliel Churata o la alegoría de “El Pez de Oro”
Authors: Velásquez-Garambel José Luis , Sucari Wilson
Published: October 2022

La imagen de Churata se ha convertido en un tótem a cuya complejidad cultural han acudido exploradores desde las más diversas regiones epistemológicas, y para esta travesía de la comprensión se han equipado con los mejores presupuestos teóricos posibles; pero su halo es lúdico y socarrón, es como la naturaleza de un pez que se escabulle por entre las manos, cuyas simbologías como sus escamas la hacen difícilmente penetrable a la razón del explorador, de tal modo que el humor y la reflexión, como parte de los “juegos originarios” son el soporte de una “chinkana” mimética que Churata conoce y reestructura a la perfección y las entremezcla como si tratara de desentrañar un proceso paralelo de “des-adoctrinamiento capitular” de la doctrina filosófica occidental, estética, religiosa, política, hasta del conocimiento y la deontología, situándola en el centro de la configuración de los saberes que están estrechamente vinculados con lo “tradicional”. Así, no solo, se convierte en un arquitecto desobediente de las estructuras de la razón, sino en un “latinoamericano” que busca una independencia epistemológica en la médula de la razón que colonizó los saberes de las culturas tradicionales del orbe europeo y latinoamericano. La lucha de Churata alcanza una dimensión tensa y llena de conflictos en un escenario teórico en el que el lenguaje y la construcción de significados abren puertas en un siglo donde la lucha por el dominio de los territorios imaginarios será crucial, “el derecho a pensar distinto” y a “saberse diferente”, en donde el sometimiento físico se halla al alcance de la tecnología bélica (como la impulsada por Estados Unidos contra Irak en el 2003, que ocasionó las tensiones en Medio Oriente hasta nuestros días o lo que viene ocurriendo en el Norte de África, en Gaza). En nuestro escenario el territorio en disputa, todavía es el imaginario social, en los años que vienen será el físico, nos hallaremos empujados y reprimidos por las políticas económicas y por el control de los recursos estratégicos bajo el dominio de empresas extranjeras, ese día el Pez de Oro habrá muerto y no quedará ningún siluro en el corazón del hombre andino. Bajo esta consideración ¿Cuál es la naturaleza ideológica y temática de El Pez de Oro de Gamaliel Churata, libro que, por demás, ha generado diversos estudios y explicaciones a vacíos epistemológicos? ¿Se trata de un texto oral con una cartografía simbólica oculta que se revela solo a los elegidos con marcada competencia cultural del mundo aimara y quechua? ¿Cuál es la naturaleza textual e hipertextual a la que alude en los mitos tradicionales y personales que construye y deconstruye Churata?
Angular Contact Ball Bearing Modeling with Different Types of Coatings
Authors:   Department of Mechanical & Manufacturing Engineering (JKMP), University Kebangsaan Malaysia, Bangi, 43600, Malaysia., Loom B.T. , Zamri W.F.H.W. ,   Department of Mechanical & Manufacturing Engineering (JKMP), University Kebangsaan Malaysia, Bangi, 43600, Malaysia., Ariffin A.K. ,   Department of Mechanical & Manufacturing Engineering (JKMP), University Kebangsaan Malaysia, Bangi, 43600, Malaysia., Md Din M.F. ,   Faculty of Engineering, National Defence University of Malaysia, Malaysia., Shamsudeen A. ,   Department of Mechanical & Manufacturing Engineering (JKMP), University Kebangsaan Malaysia, Bangi, 43600,  Malaysia.
Published: October 2022

The purpose of this study is to determine the stress distribution of uncoated and coated ball bearings by using finite element analysis. The coatings used in this study are titanium nitride (TiN), titanium carbide (TiC) and chromium nitride (CrN) with a thickness of 5 microns. A contact analysis has been performed on ball bearings to compare the performance between coated and uncoated ball bearings. Boundary loads of 5000 N is used for contact analysis. This study tries to establish a simple, two-dimensional expression for the elastic deformation with the inner ring and ball bearing as a angular or curvature model in terms of the geometry of the coating contact surfaces. The coating of ball and raceway surfaces is a requisite but difficult factor to be determined during design, so it is desirable for engineering to understand the effect of surface coating on the motion of ball and subsurface stresses in bearing. For contact analysis, the maximum contact pressure and maximum stress on the coating, inner ring and ball bearing have been used for comparison. The results of this study show that, among other coatings, TiC provides the best protection for the ball of the ball bearing. This is because the low Poisson's ratio of TiC in other coated ball bearings helps reduce the stress on the ball bearing, even though TiC has the lowest Young's modulus in the coating. When a lower boundary load is applied, high COF will also cause an abnormal increase in the maximum stress on the contact surface between the coated or uncoated ball and the inner ring of the ball bearing.
Artificial Intelligence Based Optimal Placement of PMU
Authors:   Department of Electrical Engineering, Shri Govindram Seksaria Institute of Technology and Science Indore (M.P), India, Pandey Rachana , Verma Dr. H.K. ,   Department of Electrical Engineering, Shri Govindram Seksaria Institute of Technology and Science Indore (M.P), India., Parakh Dr. Arun ,   Department of Electrical Engineering, Shri Govindram Seksaria Institute of Technology and Science Indore (M.P), India, Khare Dr. Cheshta Jain ,   Department of Electrical Engineering, Shri  Govindram Seksaria Institute of Technology and Science Indore (M.P), India
Published: October 2022

The investigation of power system disturbances is critical for ensuring the supply’s dependability and security. Phasor Measurement Unit (PMU) is an important device of our power network, installed on system to enable the power system monitoring and control. By giving synchronised measurements at high sample rates, Phasor Measurement Units have the potential to record quick transients with high precision. PMUs are gradually being integrated into power systems because they give important phasor information for power system protection and control in both normal and abnormal situations. Placement of PMU on every bus of the network is not easy to implement, either because of expense or because communication facilities in some portions of the system are limited. Different ways for placing PMUs have been researched to improve the robustness of state estimate. The paper proposes unique phasor measurement unit optimal placement methodologies. With full network observability, the suggested methods will assure optimal PMU placement. The proposed algorithm will be thoroughly tested using IEEE 7, 9, 14, and 24 standard test systems, with the results compared to existing approaches.
Local Oscillator Phase Noise Impact on M-ary Modulation Schemes
Authors:   DEETC, Instituto Superior de Engenharia de Lisboa and Centre of Technology and Systems, Lisbon, Portugal., Fialho Vitor , Fortes Fernando ,   DEETC, Instituto Superior de Engenharia de Lisboa and Instituto de Telecomunicações, Lisbon, Portugal.
Published: October 2022

This paper presents the impact of a local oscillator phase noise on digital modulation schemes based on bit error rate and error vector magnitude. The adopted methodology enables base band metrics estimation which is dependent of a specific communication standard. A generic local oscillator phase noise model is presented to evaluate the impact of different phase noise values on error vector magnitude and bit error rate. For a phase noise of -65dBc @ 1kHz the error vector magnitude changes from 7% to 12.8%. Increasing the modulation order leads to bit error rate increment for the same phase noise value.
ANALISIS DAN PERANCANGAN SISTEM INFORMASI PERSEDIAAN BARANG PADA TOKO XYZ
Authors: G. Gani Alcianno
Published: October 2022

Abstract The Inventory Information System in XYZ Store still uses the manual method, namely by recording books. With the creation of a Web-based Inventory Information System, it is hoped that it can assist in managing inventory and provide accurate information for users. This Goods Inventory Information System can assist in managing inventory, providing detailed information on the purchase of goods, demand for goods and report data on purchases of goods and requests for goods. This inventory information system is designed and built using the PHP programming language and MySQL database. Keywords: Inventory of goods, Purchase of Goods, Demand for goods, Information System, PHP, MySQL.
SCORRE approach as an instrument for detecting fraudulent financial reporting
Authors: Hermiyetti
Published: October 2022

This study aims to analyze S.C.O.R.R.E. (stimulus, capability, opportunity, capability, cooperation, and ego) as the cause of financial statement fraud. The study was conducted on B.U.M.N. companies in Indonesia as a population with published financial statement analysis units with a total of 122 as samples obtained by purposive sampling technique after being selected for the period 2014-2018 (five years). The Binary Logistics regression technique is used in analyzing data with the dependent variable using a nominal scale (0-1) as a measurement of financial statement fraud. The study concludes that not all measurement dimensions are predicted to affect the occurrence of fraud in financial statements, while measurements using other dimensions prove a significant influence on the event of financial statement manipulation. The study results provide a reference to the potential for preventing financial statement fraud by identifying several measurement dimensions that can trigger financial statement fraud. Research using Binary Logistics regression would be better confirmed through observation, either by interview or primary data that supports and predicts the results of the analysis that was not carried out in this study, so the conclusions obtained have not fully concluded the existing phenomena.
The role of environmental commitment and green creativity on business performance mediated by circular economy implementation
Authors: Ayu Widhiastuti  , Muafi Muafi
Published: October 2022

This study aims to examine and analyze the influence of green creativity and environmental commitment on business performance by considering the mediating influence of circular economy implementation in batik craft small and medium industries in Sleman Regency. This study is carried out using a quantitative method, with several samples of 120 respondents, the owner or manager of the natural dye batik crafts enterprise in Sleman Regency. The sampling technique is using a non-probability sampling technique. The data is collected by distributing questionnaires electronically. The research variables used in this study are green creativity and environmental commitment as the exogenous variable, business performance as the endogenous variable, and circular economy implementation as mediating variable. The data analysis is carried out using Partial Least Square (PLS) with the software of SmartPLS 3.0. The results of this study show that: (1) Green creativity has a significant favorable influence on the business performance of batik craft SMEs in Sleman Regency; (2) Environmental commitment has a significant positive influence on circular economy implementation; (3) Circular economy implementation has a significant positive influence on business performance, and (4) Circular economy implementation is not proven as mediating variable in the relationship of environmental commitment and business performance in batik craft SMEs in Sleman Regency. This study provides suggestions for batik owners to increase the creation of product samples for customers by utilizing virtual services to reduce the exploitation of natural resources. Further research is required at different times since this study is carried out during the Covid-19 pandemic.
Effects of digital marketing practices on performance of insurance sector
Authors: Kajwang Ben
Published: October 2022

Digital marketing practices have had explosive growth in the past decade, especially in the insurance sector of developing countries. In particular, the internet has been instrumental in providing digital marketing services to customers from the insurance sector. The purpose of this study, therefore, is to assess the effect of digital marketing practices on the performance of the insurance sector. A desktop literature review was used for this purpose. Relevant seminal references and journal articles for the study were identified using Google Scholar. The inclusion criteria entailed papers that were not over ten years old. The study found that the use of digital marketing strategies has a positive effect on the insurance sector's performance. Profitability improved, market share grew, and they expanded their market share. Increased customer loyalty and access to new markets are benefits of internet marketing for insurance companies. According to the findings, insurance companies should make IT infrastructure investments and implement technology-enhanced processes. Employers require adequate training on the use of e-business platforms, as well as collaboration with providers of digital services to enable them to store and market their products and services online. Aside from using traditional marketing methods (such as direct mail), the study advises general insurance companies to be innovative by implementing new strategies, such as digital marketing, to gain a larger share of their target market. This is because strategies for digital marketing have a positive impact on the overall performance of the insurance industry.
Factors influencing accountability practices in managing NGOs funds
Authors: Abdullah Ahmed Abdulwahed Hamoud , Zainol Zaini , Mokhtar Norsyahida
Published: October 2022

This study examines the factors influencing accountability practices in funds management of local non-governmental organizations (NGOs) in Yemen. A total of 75 local NGOs operate in Yemen, receiving local and foreign funding. A structured online questionnaire was employed for data collection. This study found that accountability was not widely practiced among the NGOs in Yemen. The level of accountability practices of these NGOs was significantly influenced by funding competition and perceived motive. The results of the study offer important implications for both policymakers and NGOs. The relevant regulatory bodies must formulate policies to enhance the NGOs’ accountability for improved efficiency and transparency. The NGOs, on the other hand, are expected to be transparent in ensuring the resources are well managed, and services are delivered efficiently and effectively to the recipients.