bluuebunny/crossref_metadata_2025 huggingface dataset:
Penerapan Teknologi Skimming dan Bioremediation pada Instalasi Pengelolaan Air Limbah di PT. Waruna Shipyard Indonesia
Authors: Siregar Munawar Alfansury , Damanik Wawan Septiawan , Lubis Sudirman , Nasutioon Arya Rudi , Arif Arfian
Published: December 2023

Water pollution causes environmental damage and is very detrimental to living things. This activity aims to improve the performance of the Wastewater Management Installation (WWTP) which functions to reduce pollutant levels in the waters. Through the collaboration of the UMSU Faculty of Engineering with PT. Waruna Shipyrad Indonesia (WSI), collaboration was also carried out to improve the performance of the wastewater management system. Wastewater management methods are carried out by applying skimming machine technology, and several sensors for the physical properties and composition of water, as well as using remediation of good bacteria from the laboratory. 6 WWTP ponds were implemented, each with dimensions of 3.7x2.8x2.17 m. The skimming machine is designed to use a drum, and the bacteria from the remediation process will suppress the growth of bacteria that damage the environment. The volume of water entering the reservoir is around 207,200 kg/m3 perweek or 207.2 Liters/week. The results of applying this technology obtained an average amount of oil taken every 2 days reaching 600 mL. The average water quality is 6-8 with a pH standard of 6-9, a COD value of 47.8 mg/L with a quality standard of 100 mg/L, and a BOD value of 21.1 mg/L with a quality standard of 30 mg/L.
Edukasi tentang Potensi Daun Sambiloto sebagai Penguat Sistem Imun Tubuh terhadap Covid-19
Authors: Sianipar Erlia Anggrainy , Marcella Sherleen , Liliana Merry , Tiono Yovita viona , Edyson Dino Claudio Signory Putra , Buntoro Leonardo , Nanda Karmill Tri , Siswandi Alodia Jeconiah
Published: December 2023

The immune system greatly influences the increasing positive cases and death of Covid 19. In order to increase public knowledge about the use of herbal plants as a booster for the immune system, the Pharmacy Study Program at the Atma Jaya Catholic University of Indonesia was holding activities for community dedication by providing education about the potential of Sambiloto leaves in preventing Covid-19 infection. This education was aimed at social media users, given a seven-minute video shared on Youtube. The video link was shared through social media Instagram, WhatsApp, and Line. The video was uploaded to Youtube on April 18, 2021, then after two weeks, followed by filling out a questionnaire by the viewers using a Google form until May 2, 2021. The results show that 1,929 viewers, 354 likers, and 305 respondents filled out the questionnaire. The questionnaire results also showed that over 90% of respondents increased their knowledge after watching the video and could answer all the questions correctly. Thus, it can be concluded that this educational activity has succeeded in increasing the knowledge of social media users significantly and had a positive impact on changing people's behavior for using sambiloto leaves as immune boosters for the prevention and treatment of covid 19.
Pencegahan Stunting Melalui Pelatihan Pembuatan Sirup Kayu Secang dan Jeruk Sambal Kepada Ibu PKK Desa Pal IX, Kalimantan Barat
Authors: Sari Dina Yuspita , Widyasari Ratna
Published: December 2023

Desa Pal IX is one of the villages in Kecamatan Sungai Kakap, Kubu Raya Regency which is affected by stunting cases with a stunting case percentage of around 12.7 percent. Sappan wood and limau citrus contain micronutrient compounds in the form of bioactive phenolic compounds and flavonoids, as well as macronutrients in the form of fats and carbohydrates. The aim of implementing this PkM is to provide education and training in making syrup from processed sappan wood and limau citrus as a macro and micro nutrient intake for handling stunting cases in Pal IX village. In general, the stages and planned activities that carried out at this PkM are preparation for activities, implementation of activities, monitoring and evaluation. The method used is the material explanation followed by training on making syrup and how to pack it to produce syrup. The results obtained are processed syrup products from sappan wood and limau citrus. In addition, there was an increase in the average score before and after the workshop, namely an increase in knowledge from a score of 30 to 68.4. Meanwhile, the results of the activity evaluation gave an index value of 86.5%, in the very satisfied category. The workshop activities were able to provide education and skills for PKK organisation in Pal IX Village in recognizing the potential of processed sappan wood and limau citrus syrup in preventing and treating stunting and making syrup product that is rich in macro-micro nutrients.
Upaya Peningkatan Cakupan Akseptor KB Melalui Pelatihan dan Pendampingan Kader di Kampung KB Kota Padang
Authors: Erwani Erwani , Susanti Dewi , Yusefni Elda , Doni Alsri Windra , Hayati Neni Fitra , Ponda Aprizal
Published: December 2023

The incidence of unmet need family planning in Indonesia is increasing from year to year. In West Sumatra in 2017 it was 18.54%, still far from the target of reducing unmet need, total  9.91%. The high incidence of unmeet need is caused by a lack of knowledge about contraception, as well as the side effects caused by contraception. The KB village in the city of Padang has only touched 0.12% of couples of childbearing age, which is not optimal in controlling population growth. For this reason, the role of KB Village still needs to be increased through community participation and cross-sectoral integration. The aim of this econduct training and mentoring of family planning cadres in KB Village, Padang City. The method used is the participatory planning method, namely cadre training conducted 2 times pre and post test to ensure the ability of family planning cadres in implementing the program. The practical method is assisting cadres in providing education to PUS. The evaluation is carried out in two stages, namely the evaluation being carried out before the training and after the training. The final evaluation is carried out by holding meetings and evaluations with family planning cadres to find out the obstacles and follow-up plans. The result of this activity was an increase in cadre knowledge of 48.7% after training. There is an increase in the coverage of family planning acceptors in KB villages seen from the reporting of new family planning acceptors.
Peningkatan Sanitasi Sekolah Lewat Kegiatan Lomba Toilet Bersih antar Sekolah di Desa Lobu Mandiri Parigi
Authors: Christine Christine , Agustiany Dessy
Published: December 2023

Basic sanitation and enhanced healthy behavior will immediately lower the number of illnesses caused by poor sanitation. People suffer from a variety of ailments as a result of poor sanitation. Pupils spend most of their time at school, thus providing good sanitary facilities is vital for their health. This community service activity aimed to raise public awareness, particularly among school members, about the importance of sanitation facilities in schools in improving the health of school members to avoid disease infection, which can reduce attendance and learning achievement in schools at Lobu Mandiri village, Parigi Moutong. A clean toilet competition among four schools was held as the method on 21 February – 4 March 2022 in Lobu Mandiri Village. As a result of the competition, the condition of the toilets in the participating schools was improved. The cleaner toilets and the availability of sufficient water made students feel more comfortable using them. Another method required to improve sanitation is health education for school members and the children's parents.
Pemberian Terapi Kelompok pada Lansia di Panti Werdha Kota Salatiga
Authors: Rayanti Rosiana Eva , De Fretes Fiane , Desi Desi
Published: December 2023

The increasing number of older people in Indonesia impacts the care process. Culturally, the eldest in Indonesia are cared for by other family members. On the other hand, several older people live in nursing homes during their old age. While in the nursing home, the eldest are cared for by health workers or nursing home administrators physically, psychologically, and spiritually to maintain or improve their quality of life. However, the elderly living in three retirement homes in Salatiga City are at risk of non-communicable diseases such as hypertension (70%) and high cholesterol (23%), loneliness, and sleeplessness (41%). The purpose of the community service is to provide group activities therapy to older people living in nursing homes. The activities included cognitive exercises (drawing, writing) and psychomotor (brain gymnastics and song movements). The service results showed that the eldest expression was happy and eager to follow the activities. The involvement of students also reduces the loneliness of the eldest, who have not received visits from their families for a long time. Group therapy activities can train cognitive and psychomotor skills and reduce feelings of loneliness in the elderly.
Geometry of deviation measures for triangular distributions
Authors: Wang Yuhe , Pinsky Eugene
Published: December 2023

Triangular distributions are widely used in many applications with limited sample data, business simulations, and project management. As with other distributions, a standard way to measure deviations is to compute the standard deviation. However, the standard deviation is sensitive to outliers. In this paper, we consider and compare other deviation metrics, namely the mean absolute deviation from the mean, the median, and the quantile-based deviation. We show the simple geometric interpretations for these deviation measures and how to construct them using a compass and a straightedge. The explicit formula of mean absolute deviation from the median for triangular distribution is derived in this paper for the first time. It has a simple geometric interpretation. It is the least volatile and is always better than the standard or mean absolute deviation from the mean. Although greater than the quantile deviation, it is easier to compute with limited sample data. We present a new procedure to estimate the parameters of this distribution in terms of this deviation. This procedure is computationally simple and may be superior to other methods when dealing with limited sample data, as is often the case with triangle distributions.
Association of age at first sexual intercourse and lifetime number of sexual partners with cardiovascular diseases: a bi-directional Mendelian randomization study
Authors: Zhuo Chengui , Chen Lei , Wang Qiqi , Cai Haipeng , Lin Zujin , Pan Huili , Wu Meicui , Jin Yuxiang , Jin Hong , Zheng Liangrong
Published: December 2023

Background

Limited studies have explored the association between sexual factors [age at first sexual intercourse (AFS) and lifetime number of sexual partners (LNSP)] and cardiovascular diseases (CVDs), leaving the causality inconclusive.

Methods

We performed a bi-directional Mendelian randomization (MR) study to investigate the causality between sexual factors and CVDs, including coronary artery disease, myocardial infarction, atrial fibrillation (AF), heart failure (HF), and ischemic stroke (IS). Single-nucleotide polymorphisms (SNPs) for sexual factors were extracted from the UK Biobank. Statistics for each CVD were derived from two different databases. MR estimates were calculated per outcome database and were combined through meta-analysis. Several complementary sensitivity analyses were also performed.

Results

The primary analysis suggested that AFS was causally associated with the risk of CVDs; the odds ratios (ORs) ranged from 0.686 [95% confidence interval (CI), 0.611–0.770] for HF to 0.798 (95% CI, 0.719–0.886) for AF. However, the association between AFS and IS (OR, 0.844; 95% CI, 0.632–1.126) was not consistent in the meta-analysis after excluding SNPs related to confounders. Moreover, non-significant associations were found between LNSP and CVDs. Reverse direction MR analysis showed that CVDs were not associated with sexual factors.

Conclusions

Genetic evidence suggested that AFS was causally associated with the risk of CVDs except for IS, whereas non-significant association of LNSP with CVDs was detected. Further investigation into AFS could be warranted in preventing the progression of CVDs.
Intraoperative cricothyroid muscle electromyography may contribute to the monitorization of the external branch of the superior laryngeal nerve during thyroidectomy
Authors: Aygun Nurcihan , Unlu Mehmet Taner , Kostek Mehmet , Caliskan Ozan , Isgor Adnan , Uludag Mehmet
Published: December 2023

Background

In thyroid surgery, both the recurrent laryngeal nerve (RLN) and external branch of the superior laryngeal nerve (EBSLN) should be preserved for maintaining the vocal cord functions. We aimed to evaluate whether EMG of the CTM applied after the superior pole dissection provided additional informative data to the IONM via ETT or not, regarding the EBSLN function.

Methods

The prospectively collected data of the patients, who have undergone thyroidectomy with the use of IONM for the exploration of both the RLN and EBSLN between October 2016 and March 2017, were evaluated retrospectively. Patients over 18 years of age with primary thyroid surgery for malignant or benign thyroid disease, and whom were applied CTM EMG with a needle electrode after the completion of thyroidectomy were included in the study. In the study, each neck side was evaluated as a separate entity considering the EBSLN at risk.

Results

The data of 41 patients (32 female, 9 male) (mean age, 46.7 + 9.1; range, 22-71) were evaluated. Sixty seven EBSLNs out of 26 bilateral and 15 unilateral interventions were evaluated. With EBSLN stimulation after the superior pole dissection, positive glottic EMG waveforms via ETT were obtained in 45 (67.2%) out of 67, and the mean glottic amplitude value was 261 + 191 μV (min‐max: 116‐1086 μV). Positive EMG responses via the CTM EMG were achieved from all of the 67 EBSLNs (100%) with stimulation using a monopolar probe at the most cranial portion above the area of divided superior pole vessels. The mean value of CTM amplitudes via CTM EMG obtained with EBSLN stimulation was 5268 + 3916 μV (min‐max:1215 ‐19726 μV). With EBSLN stimulation, the mean CTM EMG amplitude was detected significantly higher than the mean vocal cord amplitude (p<0.0001). The CTM EMG provided more objective quantifiable data regarding the EBSLN function (100% vs 67,2%, p<0.001).

Conclusion

In addition to the IONM via ETT, intraoperative post-dissection CTM EMG via needle electrode is a safe, simple and applicable method that may provide significant additional informative data to IONM with ETT by obtaining and recording objective quantitative data related to the EBSLN function.
Environmental characterization and cartographic modeling of wild plant habitats at the northern coastal zone of Egypt
Authors: El-Zeiny Ahmed M. , Nour-Eldin Hoda , Mohamed E. S. Said , Rebouh Nazih Y. , El-Amier Yasser A.
Published: December 2023

Assessing natural vegetation through conventional methods faces considerable constraints, such as limited geographical scope, reduced precision, a lack of historical data, high expenses and time demands. The study aims to use environmental and spectral data to identify and map natural vegetation and plant species along the Mediterranean coast of Egypt. This involves employing spatial analyses and cartographic modeling techniques, marking an initial effort in this endeavor. To fulfill this aim, a total number of 70 wild plant habitats were surveyed and sampled for further laboratory identification of plant species. Multispectral and thermal bands of Landsat imagery were processed to generate land cover map, as well as calculate Normalized Difference Vegetation Index (NDVI) and Land Surface Temperature (LST) to be integrated with the naturally grown plants in a cartographic model to predict the wild plant habitats. Coastal wild plant habitats were sparsely located and associated with a vegetation density ranging from 0.096 to 0.280 with an average of 0.167. Besides, the LST of these habitats fluctuated from 30.559 to 38.652 with an average of 34.361°C. Although the wild plant habitats at the Northern coastal region of Egypt are similar in environmental and climatic conditions, there are variability in NDVI and LST of each single habitat (pure or mixed). On the other hand, the lowest LST were associated with Erodium laciniatum/Rumex pictus and Erodium laciniatum habitats reporting 30.559 and 30.741°C, respectively. However, Lotus halophilus mixed with Ifloga spicata habitats reported the highest LST (38.652°C). The high vegetation density is mainly characterized by low LST which indicates the mixed wild plant habitats. The developed cartographic model showed a narrow strip along the Mediterranean region as highly suitable habitats for wild plant growth. The model can be used to map pure and mixed habitats of various wild plants with an accuracy exceeding 90%. The model was applied for mapping Arthrocnemum macrostachyum showing that the middle coastal region is most suitable for its growth. It’s recommended to integrate remotely sensed data with spatial analyses for the environmental analyses of natural plants. Present findings support researchers and scientists interested in environmental, botanic, and medical studies.
Impact of MICA 3′UTR allelic variability on miRNA binding prediction, a bioinformatic approach
Authors: Toledo-Stuardo Karen , Ribeiro Carolina H. , Campos Ivo , Tello Samantha , Latorre Yesenia , Altamirano Claudia , Dubois-Camacho Karen , Molina Maria Carmen
Published: December 2023

MicroRNAs (miRNAs) are small non-coding RNAs that participate as powerful genetic regulators. MiRNAs can interfere with cellular processes by interacting with a broad spectrum of target genes under physiological and pathological states, including cancer development and progression. Major histocompatibility complex major histocompatibility complex class I-related chain A (MICA) belongs to a family of proteins that bind the natural-killer group 2, member D (NKG2D) receptor on Natural Killer cells and other cytotoxic lymphocytes. MICA plays a crucial role in the host’s innate immune response to several disease settings, including cancer. MICA harbors various single nucleotide polymorphisms (SNPs) located in its 3′-untranslated region (3′UTR), a characteristic that increases the complexity of MICA regulation, favoring its post-transcriptional modulation by miRNAs under physiological and pathological conditions. Here, we conducted an in-depth analysis of MICA 3′UTR sequences according to each MICA allele described to date using NCBI database. We also systematically evaluated interactions between miRNAs and their putative targets on MICA 3′UTR containing SNPs using in silico analysis. Our in silico results showed that MICA SNPs rs9266829, rs 1880, and rs9266825, located in the target sequence of miRNAs hsa-miR-106a-5p, hsa-miR-17-5p, hsa-miR-20a-5p, hsa-miR-20b-5p, hsa-miR-93, hsa-miR-1207.5p, and hsa-miR-711 could modify the binding free energy between −8.62 and −18.14 kcal/mol, which may affect the regulation of MICA expression. We believe that our results may provide a starting point for further exploration of miRNA regulatory effects depending on MICA allelic variability; they may also be a guide to conduct miRNA in silico analysis for other highly polymorphic genes.
Narrative review of application of metagenomic approaches to study the link between oropharyngeal microbiome and infectious diseases
Authors: Diallo Kanny , Missa Kouassi Firmin , Tuo Jeremie Kolotioloman , Amoikon Tiemele Laurent Simon , Bla Brice K. , Bonfoh Bassirou
Published: December 2023

Context

Viral and bacterial infections are major causes of morbidity and mortality worldwide. The oropharyngeal microbiome could play an important role in preventing invasion of viral and bacterial pathogens by modulating its content and the host’s innate immune response. Next Generation Sequencing (NGS) technologies now enable in-depth study of the genomes of microbial communities. The objective of this review is to highlight how metagenomics has contributed to establish links between changes in the oropharyngeal microbiome and emergence of bacterial and viral diseases.

Method

Two search engines, PubMed and Google scholar were used with filters to focus searches on peer-reviewed original articles published between January 2010 and September 2022. Different keywords were used and only articles with metagenomic approaches were included.

Results

This review shows that there were few articles studying the link between oropharyngeal microbiome and infectious diseases. Studies on viruses using metagenomic techniques have been growing exponentially in recent years due to the Covid-19 pandemic. This review shows that most studies still focus on the basic identification of microorganisms in different disease states and multiple microorganisms (Alloprevotella, Prevotella, Bacteroides, Haemophilus, Streptococcus, Klebsiella sp., Acinetobacter sp…), have been associated with development of infections such as childhood wheezing, influenza, Covid-19, pneumonia, meningitis, and tuberculosis.

Conclusion

The oropharyngeal microbiome, despite its importance, remains poorly studied. A limited number of articles were identified but this number has increased exponentially since 2020 due to research conducted on Covid-19. These studies have shown that metagenomic has contributed to the unbiased identification of bacteria that could be used as biomarkers of various diseases and that further research is now needed to capitalize on those findings for human health benefit.
Marvels of Bacilli in soil amendment for plant-growth promotion toward sustainable development having futuristic socio-economic implications
Authors: Mukhopadhyay Meenakshi , Mukherjee Ashutosh , Ganguli Sayak , Chakraborti Archisman , Roy Samrat , Choudhury Sudeshna Shyam , Subramaniyan Vetriselvan , Kumarasamy Vinoth , Sayed Amany A. , El-Demerdash Fatma M. , Almutairi Mikhlid H. , Şuţan Anca , Dhara Bikram , Mitra Arup Kumar
Published: December 2023

Microorganisms are integral components of ecosystems, exerting profound impacts on various facets of human life. The recent United Nations General Assembly (UNGA) Science Summit emphasized the critical importance of comprehending the microbial world to address global challenges, aligning with the United Nations Sustainable Development Goals (SDGs). In agriculture, microbes are pivotal contributors to food production, sustainable energy, and environmental bioremediation. However, decades of agricultural intensification have boosted crop yields at the expense of soil health and microbial diversity, jeopardizing global food security. To address this issue, a study in West Bengal, India, explored the potential of a novel multi-strain consortium of plant growth promoting (PGP) Bacillus spp. for soil bioaugmentation. These strains were sourced from the soil’s native microbial flora, offering a sustainable approach. In this work, a composite inoculum of Bacillus zhangzhouensis MMAM, Bacillus cereus MMAM3), and Bacillus subtilis MMAM2 were introduced into an over-exploited agricultural soil and implications on the improvement of vegetative growth and yield related traits of Gylcine max (L) Meril. plants were evaluated, growing them as model plant, in pot trial condition. The study’s findings demonstrated significant improvements in plant growth and soil microbial diversity when using the bacterial consortium in conjunction with vermicompost. Metagenomic analyses revealed increased abundance of many functional genera and metabolic pathways in consortium-inoculated soil, indicating enhanced soil biological health. This innovative bioaugmentation strategy to upgrade the over-used agricultural soil through introduction of residual PGP bacterial members as consortia, presents a promising path forward for sustainable agriculture. The rejuvenated patches of over-used land can be used by the small and marginal farmers for cultivation of resilient crops like soybean. Recognizing the significance of multi-strain PGP bacterial consortia as potential bioinoculants, such technology can bolster food security, enhance agricultural productivity, and mitigate the adverse effects of past agricultural activities.
Patient-reported experiences during and following treatment with belantamab mafodotin for relapsed/refractory multiple myeloma in the DREAMM-2 study
Authors: Cardellino Anna , Correll Julia R. , Martin Mona , Gorsh Boris , Sapra Sandhya , Popat Rakesh
Published: December 2023

Introduction

Patients with relapsed or refractory multiple myeloma (RRMM) are likely to be living with persistent symptoms, especially bone pain and fatigue, and experiencing restrictions in their physical and social functioning, which reduce health-related quality of life.

Methods

This qualitative interview study evaluated patients’ perspectives about living with RRMM and their treatment with belantamab mafodotin, using interviews embedded in the Phase II DREAMM-2 trial (NCT03525678) with belantamab mafodotin. Patients consented to participate in up to 2 recorded telephone interviews (at treatment cycle 4 [C4] and at end of treatment [EOT]) comprising open-ended questions.

Results

A total of 142 interviews were conducted with 111 unique patients. At C4, common symptoms included neuropathy, fatigue, and bone or joint pain. Improvements in symptom severity were reported by patients who responded to belantamab mafodotin. Symptoms associated with visual impairment, eye irritation, and eye pain reported during the trial were reported to be at- or near-resolution by the EOT interview. Regarding impacts of underlying MM, patients most commonly expressed concerns about changes in daily performance and lifestyle for both responders (67.5% of all impact expressions) and non-responders (63.2%). Overall, interview participants reported being satisfied with belantamab mafodotin treatment.

Discussion

This qualitative patient interview study provides valuable insight into patients’ symptomatic experience with belantamab mafodotin for their RRMM treatment and may help healthcare providers better anticipate their patients’ real-world experience and needs when prescribing this novel agent in the clinic.
CT-based radiomics nomogram for overall survival prediction in patients with cervical cancer treated with concurrent chemoradiotherapy
Authors: Xu Chao , Liu Wen , Zhao Qi , Zhang Lu , Yin Minyue , Zhou Juying , Zhu Jinzhou , Qin Songbing
Published: December 2023

Background and purpose

To establish and validate a hybrid radiomics model to predict overall survival in cervical cancer patients receiving concurrent chemoradiotherapy (CCRT).

Methods

We retrospectively collected 367 cervical cancer patients receiving chemoradiotherapy from the First Affiliated Hospital of Soochow University in China and divided them into a training set and a test set in a ratio of 7:3. Handcrafted and deep learning (DL)-based radiomics features were extracted from the contrast-enhanced computed tomography (CT), and the two types of radiomics signatures were calculated based on the features selected using the least absolute shrinkage and selection operator (LASSO) Cox regression. A hybrid radiomics nomogram was constructed by integrating independent clinical risk factors, handcrafted radiomics signature, and DL-based radiomics signature in the training set and was validated in the test set.

Results

The hybrid radiomics nomogram exhibited favorable performance in predicting overall survival, with areas under the receiver operating characteristic curve (AUCs) for 1, 3, and 5 years in the training set of 0.833, 0.777, and 0.871, respectively, and in the test set of 0.811, 0.713, and 0.730, respectively. Furthermore, the hybrid radiomics nomogram outperformed the single clinical model, handcrafted radiomics signature, and DL-based radiomics signature in both the training (C-index: 0.793) and test sets (C-index: 0.721). The calibration curves and decision curve analysis (DCA) indicated that our hybrid nomogram had good calibration and clinical benefits. Finally, our hybrid nomogram demonstrated value in stratifying patients into high- and low-risk groups (cutoff value: 5.6).

Conclusion

A high-performance hybrid radiomics model based on pre-radiotherapy CT was established, presenting strengths in risk stratification.
Structure and function of microbiomes in the rhizosphere and endosphere response to temperature and precipitation variation in Inner Mongolia steppes
Authors: Song Wenchen , Wang Yao , Peng Bo , Yang Linyan , Gao Jian , Xiao Chunwang
Published: December 2023

Introduction

Owing to challenges in the study of complex rhizosphere and endophytic microbial communities, the composition and function of such microbial communities in steppe ecosystems remain elusive. Here, we studied the microbial communities of the rhizosphere and endophytic microbes of the dominant plant species across the Inner Mongolian steppes using metagenomic sequencing and investigated their relationships with changes in mean annual temperature (MAT) and mean annual precipitation (MAP).

Methods

Metagenomic sequencing based on Illumina high-throughput sequencing, using the paired end method to construct a small fragment library for sequencing.

Results

Adaptation of root systems to the environment affected the composition and function of rhizosphere and endophytic microbial communities. However, these communities exhibited distinct community assembly and environmental adaptation patterns. Both rhizosphere and endophytic microbial communities can be divided into two unrelated systems based on their ecological niches. The composition and function of the rhizosphere microbial communities were mainly influenced by MAT, while those of the endophytic microbial communities were mainly influenced by MAP. MAT affected the growth, reproduction, and lipid decomposition of rhizosphere microorganisms, whereas MAP affected reverse transcription and cell wall/membrane/envelope biogenic functions of endophytic microorganisms.

Conclusion

Our findings reveal the composition and function of the rhizosphere and endophytic microbial communities in response to changes in MAP and MAT, which has important implications for future biogeography and climate change research.
Doing-together with words: the sequential unfolding of a moment of meeting in a psychoanalytic therapy session
Authors: Herrera Marcos , Ugarte Andrea , Vásquez-Torres Gabriela , Durand Kene M. , Sánchez Miguel
Published: December 2023

Changes in psychoanalytic therapy have been traditionally attributed to self-knowledge (insight) in the client, provided by the therapist’s interpretations. In recent years there has been growing realization that such changes can also be the consequence of the development of new forms of relatedness through client–therapist interaction, particularly through special intersubjective moments called moments of meeting. Drawing on the methods and findings of Conversation Analysis about the sequential organization of psychotherapeutic interaction, this single-case study examines the unfolding of a moment of meeting in the final session of a brief psychoanalytic therapy in Peru (in Spanish) with a female client victim of domestic violence. Our analysis shows that the moment of meeting, which resolves a challenge to the intersubjective relationship posed by a now moment, comes about interactionally through a sequentially accomplished shared practice of co-animation. In this sequence the client, who had previously assumed a passive role, exercises her own agency to assume an active role, which the therapist ratifies through his response. In this way, a momentary but significant transformation in the here-and-now relationship between client and therapist occurs. Thus, our analysis contributes to the understanding of how a transformation of relation—the transitory emergence of a new form of relatedness—can take place in and through sequentially organized talk and action in psychotherapy. Our study also sheds light on the role of language in moments of meeting, as the moment of meeting in our segment does not occur in parallel with the exchange of linguistic utterances between client and therapist, but through the exchange of such linguistic utterances and through the sequence of actions carried out by that exchange. In this way, the sequential doing-together with words leads to a moment of meeting, bringing about change, at least momentarily, in the implicit ways-of-being-with-others of the client.
Ecological drivers for poultry farms predisposed to highly pathogenic avian influenza virus infection during the initial phase of the six outbreaks between 2010–2021: a nationwide study in South Korea
Authors: Min Kyung-Duk , Yoo Dae-sung
Published: December 2023

Background

Highly pathogenic avian influenza (HPAI) has caused substantial economic losses worldwide. An understanding of the environmental drivers that contribute to spillover transmission from wild birds to poultry farms is important for predicting areas at risk of introduction and developing risk-based surveillance strategies. We conducted an epidemiological study using data from six HPAI outbreak events in South Korea.

Materials and methods

An aggregate-level study design was implemented using third-level administrative units in South Korea. Only regions with high natural reservoir suitability were included. The incidence of HPAI at chicken and duck farms during the initial phase (30 and 45 days after the first case) of each outbreak event was used as the outcome variable, assuming that cross-species transmission from wild birds was the dominant exposure leading to infection. Candidate environmental drivers were meteorological factors, including temperature, precipitation, humidity, and altitude, as well as the proportion of protected area, farm density, deforestation level, and predator species richness. Logistic regression models were implemented; conditional autoregression models were used in cases of spatial autocorrelation of residuals.

Results

Lower temperature, higher farm density, and lower predator species richness were significantly associated with a higher risk of HPAI infection on chicken farms. Lower temperature, higher proportion of protected area, and lower predator species richness were significantly associated with a higher risk of HPAI infection on duck farms.

Conclusion

The predicted dominant transmission routes on chicken and duck farms were horizontal and spillover, respectively. These results reveal a potential protective effect of predator species richness against HPAI outbreaks. Further studies are required to confirm a causal relationship.
Spatial and Temporal Variations of the Hydrochemical Parameters in the Gravelly Aquifer of the Lower Course of Vjosa River, Albania
Authors: Dindi Elsa , Shehu Ardian
Published: December 2023

Vjosa is the main river of South Albania. Currently, the confined Quaternary gravelly aquifer in its lower course supplies drinking water for roughly 300,000 local residents. In the past years, extracted groundwater quantity has increased, whereas the groundwater quality has been affected by seawater intrusion. This paper aims to assess the groundwater quality and to discuss the dominant hydrochemical processes in the aquifer. To fulfil this goal, the study discusses the groundwater quality’s spatial and temporal variations on the basis of the hydrochemical parameters and ratios for 2010–2021 period, during which data are collected from three monitoring wells, located 6, 14 and 17 km, from the sea. While for 1961–2009 period, hydro-chemical water types and TDS maps are prepared using roughly 100 chemical analyses. The hydro-chemical parameters are discussed related to the factors controlling the groundwater’s chemical constituents and the groundwater extraction. Heavy metals and nitrates’ contents indicate that the aquifer is not affected by anthropogenic pollution. The main conclusion is that the groundwater quality is affected by seawater intrusion due to overexploitation. The study reveals its gaps, mentions its possible usefulness, and underlines the discrepancy between the policy makers and the hydrogeologists approaches concerning groundwater extraction.
PENYULUHAN KESEHATAN PENDAMPINGAN PRAKTEK PEMASANGAN TENSOCREPE SENDI
Authors: Aji Rustam , Dewi Mursidah , Handayani Tri , Wahyuddi Munadiah , Ratih FSA Sherly , Ajhie Ayuningtyas Roro
Published: December 2023

Latar Belakang: Keseleo (dislocations) dapat terjadi secara tiba-tiba tanpa kita sadari,kjadiannya bisa di rumah maupun di luar rumah, pada saat bekerja, berolah raga , bermain dan lain sebagainya. Perlu penanganan yang tepat, karena tensocrepe  merupakan salah satu alat sederhana. Pada Pertolongan Pertama Pada Kecelakaan (P3K) yang dibutuhkan terutama untuk pertolongan pada korban, keseleo.Tujuan: Siswa memahami tentang keseleo dan dapat mempraktekkan dan memberikan tensocrepe pada sendi yang keseleo. Agar sendi yag cedera tidak bergeser sehingga menghindari meluasnya cedera pada jaringan otot di sekitar tulang sendi yang cedera. Hasil Kegiatan : Penyuluhan dihadiri siswa klas.IV. SDN.07 Rejang Lebong 10 siswa perempuan dan 11 laki-laki, 98 % siswa bisa menjawab kuis pertanyaan langsung tentang keseleo  dan dapat mempraktekkan dan memberikan tensocrepe pada sendi yang keseleo. Rencana Tindak Lanjut : Akan dilaksanakan kegiatan pelatihan pemasangan tensocrepe  pada kelas lainnya.Pembahasan : Pemasangan tensocrepe merupakan pertolongan pertama pada sendi yang mengalami cedera keseleo, dengan cara mempertahankan posisi sendi yang cedera  menggunakan pemasangan tensocrepe, dapat  menjaga posisi yang stabil, dan cedera tidak meluas. Kesimpulan : 98 % siswa bisa menjawab kuis pertanyaan langsung tentang keseleo  dan dapat mempraktekkan dan memberikan tensocrepe pada sendi yang keseleo (dislocations). agar ssendi yang cedera tidak bergeser sehingga menghindari meluasnya cedera pada jaringan otot di sekitar tulang sendi yang cedera. Saran: Siswa yang telah diberikan pelatihan pemasangan tensocrepe,sebaiknya melakukan sosialisasi pada teman dan keluarga.
RSE, droits de l’homme et multinationales : la doctrine du forum non conveniens est-elle un obstacle à une judiciarisation du contentieux ?
Authors: Tchotourian Ivan , Langenfeld Alexis
Published: December 2023

La doctrine du forum non conveniens permet de renvoyer un litige incluant un élément d’extranéité devant un for plus approprié. En pratique, la doctrine du forum non conveniens s’avère problématique pour les demandeurs recherchant la responsabilité des entreprises multinationales pour violation des droits de l’Homme. Comme le démontrent des affaires portées devant les juges québécois, de nombreux recours judiciaires intentés dans leur pays siège (le Canada) ont été renvoyés devant les cours des pays hôtes où la justice n’a finalement pas été rendue. La doctrine du forum non conveniens ne constitue-telle pas un obstacle critiquable à la RSE ? D’une part, la situation de vulnérabilité du demandeur et le déséquilibre de force entre les parties au litige brouillent la donne. D’autre part, de récentes décisions de justice canadiennes (Araya v. Nevsun Resources Ltd. et Garcia v. Tahoe Resources Inc.) démontrent une ouverture des cours, ces dernières semblant plus favorables aux demandeurs étrangers.
Réflexion sur l’appréhension des familles recomposées en droit successoral : l’exemple du droit anglais
Authors: Sauvé Laure
Published: December 2023

Les familles recomposées soulèvent des questions spécifiques en droit successoral. Récemment, les familles ont évolué : l’augmentation de l''espérance de vie, la composition du patrimoine du défunt – davantage constitué de biens acquis pendant le mariage plutôt que de biens hérités de sa famille –, l''émergence de nouveaux modèles de familles recomposées, impliquent de trouver des solutions adéquates. Le droit successoral français et anglais visent à établir un équilibre entre les souhaits du défunt, et les intérêts du conjoint survivant et des autres membres de la famille. Alors que le droit français confère aux proches du défunt des parts réservataires fixées par la loi, les pouvoirs discrétionnaires du juge anglais offrent plus de souplesse. Cette étude a pour but d’évaluer ces règles et de proposer de nouveaux éléments de solutions pour nourrir la réflexion dans les deux pays.
La rédaction du Code civil chinois : entre la compilation et l’innovation
Authors: Shi Jiayou
Published: December 2023

L’entreprise actuelle de codification civile en Chine est le prolongement des initiatives lancées depuis la fondation de la République populaire et devra être achevée en 2020. Démarche stratégique inscrite dans le cadre de la construction d’un «État de droit socialiste » et de la «modernisation des réseaux de gouvernance » , la rédaction du Code civil chinois a pour vocation de consolider le droit existant en rationalisant les sources du droit d’une part, et d’autre part de rénover le droit civil chinois afin de répondre aux besoins réels de la société chinoise contemporaine.
Increasing Extension Volunteer Knowledge and Preparedness with Youth Protection Training Across Program Areas
Authors: Hobbs Keri , Dorn Sheri
Published: December 2023

The University of Georgia (UGA) has a training requirement for adults working with youth. To meet this requirement for Georgia 4-H and Extension Master Gardener volunteers, a standardized online training module was created and delivered across program areas. Volunteers were surveyed to evaluate training effectiveness and experience. Understanding of UGA youth protocols and service preparedness increased after training for both volunteer groups, though preparedness may be affected by life stage, engagement in youth service roles, and/or comfort with virtual training. The module was considered accessible and convenient by respondents, thus providing a successful approach for offering trainings across program areas.
Evaluating Physical Activity Resources to Support Health Equity in Arizona
Authors: Orzech Kathryn , LeGros Theresa , Jacobs Laurel , Goodman Gregory , Lang Ryan
Published: December 2023

We evaluated physical activity (PA) resources in lower-income Arizona communities to support the Supplemental Nutrition Assistance Program – Education (SNAP-Ed) in pursuing equitable policy, systems, and environment (PSE) interventions. In 2017, 71 PA resources across 10 counties (65% parks) were rated using the Physical Activity Resource Assessment (PARA) tool. Accessibility was high, but condition scores and attractiveness varied across resources, with no rural/urban differences. Results suggest that Extension SNAP-Ed staff can be agents of change by assessing resource condition where physical activity health inequities may exist and then convening partners to begin to address needed changes.
Constitutional principles of economic, administrative, and criminal responsibility in the field of insurance
Authors: Biletska Liudmyla , Saray Roman , Dontsov Denys , Lozynskyi Yurii , Hryshchuk Alina
Published: December 2023

The constitutional principles of legal liability are an important prerequisite for the introduction of economic, administrative and criminal liability in the insurance sector. The Constitution enshrines the guiding provisions on legal responsibility in general, which later find their consolidation in separate special acts, in particular, those regulating relations in the insurance sphere. The purpose of the work is to clarify the peculiarities of the constitutional regulation of economic, administrative and criminal responsibility in the field of insurance. The research methodology consists of such methods as: dialectical, analysis, synthesis, formal-logical, historical, systemic. The article analyzes the peculiarities of bringing business entities to account in the insurance sector. It was noted that the Constitution of Ukraine establishes the general principles of bringing to legal responsibility, while special legislation establishes direct requirements for bringing to responsibility in certain spheres of socio-economic life. Problematic issues of prosecution in the field of insurance and international experience on this issue have been studied in order to formulate scientifically based conclusions.
Gender semiology in folklore traditions: Russia, China and Adygea
Authors: Khachmafova Zaineta R. , Karabulatova Irina S. , Unarokova Raisa B. , Tseeva Zarema A. , Zhang Ludan , Loseva Ruslana V.
Published: December 2023

The article presents an analytical analysis of the linguosemiotic features of the female portrait in the folklore fund of the linguocultures of Russia, the North Caucasus and China in the aspect of the intergender dichotomy "male-female" as the implementation of the policy of "soft power" of the ethnos to preserve its vitality. Hypothesis: The dichotomy of masculinity and femininity in traditional culture is presented as the result of the interaction of ethno-cultural strategies of the ancestral cult, in which the role of a woman is defined as the keeper of the knowledge of the people with the competencies of a housewife who needs help and care from a man. The relevance of the study is due to the growing research interest in the vitality of traditional cultures, which continue to influence the lives of modern women. Chinese, Adyghe and Russian folklore for the first time becomes the object of comparative analysis of the linguosemiotic characteristics of the image of femininity in the form of "feminine" folkloratives identified for the first time. The methodology uses a linguosemiotic approach and the theory of complex metagraphs in modeling the speech-behavioral gender matrix of women through the prism of folklore. The results show that folklore is a reproducible mechanism of "soft power" of gender regulation in the ethno-cultural practice of folk art.
The problem of child safety in the digital space
Authors: Lubenets Iryna , Kulyk Oleksandr , Kulakova Nataliia , Lisnychenko Liliia , Naumova Iryna
Published: December 2023

The rapid development of digital technologies has transformed the lives of children and young people. The digital space offers children endless opportunities to learn, play, communicate and express themselves. However, it also poses a number of risks and threats, such as cyberbullying, grooming and exposure to harmful content. The purpose of this article is to analyze the current state of the criminological safety of a child in the digital space based on a survey among Ukrainian schoolchildren aged 11-17. Our task is to determine the level of awareness of teenagers about safe behavior on the Internet, as well as to identify the most common threats and assess the level of risky behavior of Ukrainian children on the Internet. The article emphasizes that the range of threats to underage Internet users is much wider than to adults due to the peculiarities of this age group. Empirical research shows that schoolchildren tend to act rather carelessly in the digital space, particularly in regards to making new contacts and communicating online. We believe that the family and the school should play the dominant role in familiarizing children with existing online threats and the fundamentals of safe behavior in the digital space.