bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluation of IL-38, a Newly-Introduced Cytokine, in Sera of Vitiligo Patients and Its Relation to Clinical Features
Authors: Zarrabi Maryam , Gholijani Nasser , Amirghofran Zahra , Sadati Maryam Sadat , Radanfar Roya
Published: January 2024

Introduction: Vitiligo is thought to be an autoimmune disorder caused by melanocytes dysfunction and depigmentation. Among different executors of the immune system in developing the disease, the role of various cytokines has been defined.
Objectives: We have focused on IL-38, the tenth member of IL-1 cytokine family with a proposed anti-inflammatory role, which has not hitherto been introduced as an anti-inflammatory factor in vitiligo.
Methods: Sixty-nine generalized vitiligo patients and 72-year-old- and sex-matched healthy individuals were included in this study. IL-38 level was evaluated in sera of all participants using ELISA assay. The relation of IL-38 level to patients characteristics was evaluated.
Results: IL-38 serum level in vitiligo patients (159.5±39.7 pg/ml) was lower than the healthy controls (166.7±34.8pg/ml) (P = 0.039). A weak negative correlation between the age of male patients and their IL-38 serum levels was identified (r = 0.38, P = 0.058). Evaluation of the IL-38 serum levels relationship with patients clinical characteristics showed no correlation with disease onset, stage of depigmentation, and disease activity status.
Conclusions: The lower levels of IL-38 as an anti-inflammatory cytokine support the inflammatory nature of vitiligo. It indicates the difference of IL-38 in sera of vitiligo patients and healthy controls, as the first report of the lower level of this cytokine in the context of vitiligo. The reason of this difference remains to be clarified; as there are not sufficient study reports revealing the role of gender, ethnicity and inflammation on the cytokine network in the context of vitiligo.
Familial Melanoma Phenotype With Xeroderma Pigmentosum Group C (XP-C) Genotype - The Putative Role of MC1R Polymorphism as Modifier
Authors: Leidenz Franciele Antonieta Bianchi , Bittencourt Flavia Vasques , Braga Williana Garcia , Araujo Ellio Magno de Sá , Gomes Carolina Cavalieri , Bernardes Vanessa de Fatima , Friedman Eitan , De Marco Luiz
Published: January 2024

Introduction: Xeroderma pigmentosum (XP), a rare inherited condition, hallmarked by extreme sensitivity to sun exposure resulting in multiple skin cancers and non-malignant skin alterations is attributed to homozygous inactivating pathogenic variants (PVs) in DNA repair genes, predominantly the XPC gene.
Objectives: Report a unique phenotypic expression of mutant XPC allele that may be compatible with a putative modifier role for MC1R polymorphism.
Methods: A family of 13 siblings, seven of whom were diagnosed with at least one cutaneous  melanoma (N = 53) and non-melanoma skin cancers (N = 9) was studied. Of seven melanoma-affected cases, five consented for genetic analysis. CDKN2A revealed no PV in any case and subsequent whole-exome sequencing (WES) identified a rare homozygous missense PV (c.919C>T; p.Arg307Trp) in exon 8 of the XPC gene in all affected individuals. Notably, XPC PV carriers who co-harbored the p.I155T MC1R variant (N = 3) exhibited larger number of tumors, deeper Breslow indexes, higher rates of invasive melanomas and earlier age at diagnosis compared with non MC1R variant carriers (N = 2).
Conclusions: Familial malignant melanoma phenotype may, in fact, be an unusual clinical presentation of XPC, and MC1R may be a genetic modifier of penetrance and phenotype of mutant XPC alleles.
Sustainable Water Management: An Integrated Approach to Solving the Problems of Wastewater Treatment
Authors: Lako Alfred , Çomo Elvin
Published: January 2024

The relevance of the study of this problem today lies in the fact that the awareness of the lack of water resources and the threat of environmental pollution forces us to focus on the development of sustainable water management solutions. In the context of population growth, water pollution and climate change, it is necessary to respond quickly and improve wastewater treatment methods, assess their impact on the environment and improve water supply systems to ensure stable and environmentally safe access to water resources for future generations. The purpose of this article is to consider an integrated approach to solving the problems of wastewater treatment, assessing their impact on the environment, and improving the water supply system to build a sustainable water economy. Among the methods used, it should be noted the analytical method, the classification method, the functional method, the statistical method, the synthesis method, and others. Water management and environmental protection research included analysis of wastewater treatment technologies, environmental impact assessment, development of water supply systems, municipal waste management, hydrological processes, environmental pollution, use of renewable energy, risk assessment and soil erosion. The effectiveness of wastewater treatment systems, the need for technology improvement, the impact of some types of industry and agricultural activity on the environment, the need to modernize water supply systems, effective management of urban waste, conservation of water resources and prevention of soil erosion were revealed. Research results indicate the need to develop strategies and policies to preserve water resources and improve the state of the environment. This research makes a significant contribution to science, contributing to the development of sustainable water management by developing an integrated approach to solving the problems of wastewater treatment, assessing their impact on the environment, and improving the water supply system.
Cerebral Amyloid Angiopathy: An Undeniable Small Vessel Disease
Authors: Wang Litao , Liu Qiong , Yue Dongqi , Liu Jun , Fu Yi
Published: January 2024

Cerebral amyloid angiopathy (CAA) has been proven to be the most common pathological change in cerebral small vessel disease except arteriosclerosis. In recent years, with the discovery of imaging technology and new imaging markers, the diagnostic rate of CAA has greatly improved. CAA plays an important role in non-hypertensive cerebral hemorrhage and cognitive decline. This review comprehensively describes the etiology, epidemiology, pathophysiological mechanisms, clinical features, imaging manifestations, imaging markers, diagnostic criteria, and treatment of CAA to facilitate its diagnosis and treatment and reduce mortality.
Standard Versus Intensive Blood Pressure Control in Acute Ischemic Stroke Patients Successfully Treated With Endovascular Thrombectomy: A Systemic Review and Meta-Analysis of Randomized Controlled Trials
Authors: Park Hyungjong , Sohn Sung-Il , Leem Gwang Hyun , Kim Minho , Kim Yun Hak , Song Tae-Jin
Published: January 2024

Background and Purpose The optimal blood pressure (BP) control after successful endovascular thrombectomy (EVT) in acute ischemic stroke (AIS) with large vessel occlusion (LVO) remains debatable. We conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) that evaluate the efficacy and safety of standard BP control (with systolic BP ≤180 mm Hg) versus intensive BP control (systolic BP <140 mm Hg) during the 24 hours after successful EVT in AIS with LVO.Methods PubMed, Scopus, the Cochrane Central Register of Controlled Trials, and Embase were searched to identify relevant trials. The crude odds ratio (OR) and 95% confidence interval (CI) were calculated and estimates using random-effects models were pooled. This meta-analysis followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines (PROSPERO ID: CRD42023450673).Results Four RCTs involving 1,559 participants were included. Regarding efficacy outcomes, intensive BP control was associated with a lower likelihood of functional independence (OR: 0.68; 95% CI: 0.51–0.91 for modified Rankin Scale [mRS] ≤2) and walking without assistance (OR: 0.65; 95% CI: 0.53–0.81 for mRS ≤3). For safety outcomes, consistent with the efficacy findings, intensive BP control was significantly associated with severe disability or death (mRS 5 or 6) (OR: 1.34; 95% CI: 1.07–1.69). However, there were no significant differences including all-cause mortality, any intracerebral hemorrhage (ICH), symptomatic ICH, parenchymal hematoma type 2, and stroke recurrence.Conclusion While all four RCTs were conducted to demonstrate the superiority of intensive BP control over standard BP control, standard BP control may be beneficial for the outcome after EVT for AIS with LVO without increasing adverse safety outcomes. Caution should be needed with the application of intensive BP control during the 24 hours following successful recanalization after EVT.
استخدام طريقة المحادثة لنجاح تعلم اللغة العربية بمعهد المنورة عيمفلاك عوديريجو ديويك جومبانج
Authors: Zamzami Nurfaizi , Qodir Abdul
Published: January 2024

Arabic is a very important language to learn and requires a lot of time to learn it. Therefore, because learning Arabic is quite complicated, it is necessary to use various methods of learning Arabic so that learning Arabic can be carried out properly and conducively. One way that I use is to use the muhadasah or maharah kalam method. The muhatdasah method is a conversation between two or more people who are mutually reciprocal. In learning Arabic, Muhadatsah lessons are intended to facilitate communication skills (Maharah Kalam or Maharah Lughah) between one another. This Maharah Kalam is the essence of learning Arabic, being able to communicate both directly and indirectly using Arabic. The researcher used qualitative methods, therefore the researcher went down to the field and interviewed several sources. And why did I take the research location at Pondok Almunawaarah because Arabic is well known which is quite popular in the field of language. The results of scientific research show that the use of the conversational method is a success in learning Arabic at the Al-Munawwarah boarding school, ngeplak ngudirejo, diwek Jombang. daily conversations and supported by Arabic speaking teachers.
Faktor Kepopuleran Kajian Dr. H. Fahrudin Faiz, S.Ag., M.Ag. di Kalangan Generasi Z
Authors: Afifah Sarah , Arwani M. Khairul
Published: January 2024

This research investigates the factors that contribute to the appeal of Dr. Fahrudin Faiz's religious studies among Generation Z. In an era where the delivery method and popularity significantly influence religious outreach (Dakwah), this study aims to understand the dynamics of engaging young audiences. A qualitative field research method, comprising observation, interviews, and documentation, is utilized to gather data. The study seeks to offer comprehensive insights into Generation Z's motivations and preferences concerning religious teachings. The findings are anticipated to assist educators, researchers, and stakeholders in developing improved communication strategies for imparting religious values in today's digital world. This research not only highlights the intersection of religion and modern communication channels but also addresses the specific needs and interests of younger generations in religious education.
Educação em Jogo: Os possíveis aspectos negativos do uso da gamificação nos processos de ensino na educação profissional e tecnológica
Authors: Moraes Tatiane Netto , Nakamoto Paula Teixeira
Published: January 2024

A gamificação tem sido apontada por muitos como a solução para motivar e trazer comprometimento em diversas áreas, mas a gamificação realmente é boa para todos? Muitas pesquisas têm mostrado as vantagens da utilização da gamificação, porém, ainda são poucos os trabalhos voltados a pesquisar as desvantagens. Esta pesquisa procura identificar os aspectos negativos que podem surgir através do uso da gamificação nos processos de ensino na educação profissional e tecnológica, sobretudo no Ensino Médio Integrado. Assim, partindo da premissa que os estudantes do Ensino Médio Integrado se encontram no período da adolescência, e que nessa fase a maioria deles estão vivenciando um período da vida de intensas transformações, precisamos examinar se em meio a esse turbilhão de descobertas e emoções, a gamificação não traz impactos negativos para esse grupo de alunos, já que a gamificação tem relação direta com componentes emocionais. Esse artigo é uma síntese da pesquisa de dissertação do Programa de Pós-Graduação em Educação Profissional e Tecnológica (PROFEPT). A pesquisa tem uma abordagem quali-qualitativa e procedimento bibliográfico.  Espera-se que esses resultados possam auxiliar os docentes na melhoria do processo de ensino-aprendizagem, para que, ao decidirem utilizar a gamificação como recurso pedagógico possam encontrar subsídios que os auxiliem a reconhecer e então eliminarem, ou ao menos minimizarem, esses aspectos negativos.
Formação continuada de docentes não licenciados que atuam na Educação Profissional e Tecnológica: o que revelam as pesquisas no período de 2016 a 2021
Authors: Tunes Elisane Ortiz de , Barreiro Cristhianny Bento
Published: January 2024

Este artigo é resultado de uma pesquisa do tipo Estado do Conhecimento, a qual se propõe uma síntese analítica de pesquisas publicadas entre os anos de 2016 e 2021, tendo como foco de investigação a formação de professores não licenciados que atuam na Educação Profissional e Tecnológica, especificamente no que tange a sua formação continuada. Foram inventariadas as produções acadêmicas na Biblioteca Digital de Teses e Dissertações e no Portal de Periódicos da CAPES, utilizando os descritores “Educação Profissional e Tecnológica” e “Formação de Professores” ou “Formação Docente”. Dezesseis trabalhos compuseram o corpus de análise, com vistas a construir resposta para questão: como a formação continuada de docentes, que atuam na formação profissional da Educação Profissional e Tecnológica, vem sendo discutida nas produções acadêmicas entre os anos de 2016 e 2021? Os resultados apontam que, embora a formação de professores da Educação Profissional e Tecnológica tenha conquistado espaço nas pesquisas dos últimos anos, o tema ainda carece de maiores estudos que discutam a formação continuada e que apontem proposições para a concretização deste tipo de formação no contexto de atuação docente, buscando sua consolidação na rotina das instituições de ensino técnico e profissional.
ANALISA DAN IMPLEMENTASI ALGORITMA C4.5 UNTUK KLASIFIKASI DURASI KONTRAK KERJA (Studi Kasus Pada PT Ciptajaya Kreasindo Utama Bekasi)
Authors: Ibrahim Anwar
Published: January 2024

PT Ciptajaya Kreasindo Utama Bekasi yang berada di Kawasan Industri MM2100. Menentukan durasi kontrak kerja bagi karyawan yang diterima sesuai dengan peraturan pemerintah yang berlaku. Belum adanya kalkulasi dalam menentukan durasi kontrak yang tidak bisa dipertanggungjawabkan secara real. Menerapkan Algoritma C4.5 untuk membuat perusahaan ini bergerak dengan baik dan jelas untuk menentukan durasi kontrak kerja yang valid dan sesuai dengan peraturan yang berlaku. Inputan yang digunakan yaitu berupa atribut dari data karyawan kontrak yaitu Nilai Absensi, NC Produk, Cust.Claim, Surat Peringatan, dan Koteipro. Data karyawan kontrak tersebut digunakan untuk data sampel training yang digunakan untuk menyusun pohon keputusan. Hasil dari implementasi Algoritma C4.5 untuk klasifikasi durasi kontrak kerja adalah klasifikasi durasi kontrak kerja 6 bulan, 10 bulan, 12 bulan, 13 bulan, 14 bulan, 15 bulan, dan 16 bulan berdasarkan atribut yang sudah ditentukan.
The Rational Expectations Hypothesis of the Term Structure at the Polish Interbank Market
Authors: Blangiewicz Maria , Miłobędzki Paweł
Published: January 2024

We use a three-variable VAR including the yield spread, the change in the short rate and the excess holding period yield to test for the validity of the rational expectations hypothesis (REH) at the Polish interbank market. In doing so we utilize the set of monthly sampled WIBORs (Warsaw Interbank Offered Rates) for maturities of 1, 3, 6, 9 and 12 months from the period January 1999-December 2007. Although the yield spread Granger-causes future changes in the short rate for all maturities the other testing results are somewhat ambiguous. We find the restrictions set on the VAR that the one-period excess holding period return is not time varying should be rejected for all maturities. So should be the restrictions stating the actual spread equals the theoretical spread, except for 12 month WIBOR. Nevertheless, the estimates of conventional VAR metrics such that correlation coefficients between the actual and the theoretical spread and their variance ratios to some extent support the REH in its pure form (PREH). The first are all very close to unity and the latter are less than two standard deviations from unity for 3 month maturity. The conclusions in favour of the PREH for 9 and 12 month maturities are reached upon the bootstrapping experiment in which we have estimated the 95 per cent confidence intervals for the variance ratios. The estimates of the other VAR metrics suggest that a relatively large piece of variation in the unexpected return is due to news about future short rates and not due to news about the future average term premium.
Metody prognozowania z wykorzystaniem trendu potęgowego
Authors: Purczyński Jan
Published: January 2024

In this paper selected aspects concerning the use of power trend in the forecasting process were considered. Approximate methods for estimating trend parameters (equations (12)-(15)) were proposed. The methods yielded results similar to results given by least squares method (LSM). Formula (35) determining ex ante error of the forecast determined by the approximate methods and LSM for random element additive model was defined. Computer simulations were done – including three models of random element (additive, multiplicative, mixed) – with the aim of determining the range of usefulness of logarithmic transformation method, LSM and the approximate methods.
Wykorzystanie entropii Shannona i jej uogólnień do badania rozkładu prawdopodobieństwa zmiennej losowej dyskretnej
Authors: Wędrowska Ewa
Published: January 2024

Everywhere where there is need for identification and measurement of indeterminacy of the distributions studied we can talk about entropy. The need to measure the degree of diversity occurs in studies on numerous systems, processes and phenomena, in particular in studies on socioeconomic phenomena. That is why in studies on those phenomena the measures or models defined on grounds of the information theory are used increasingly often. The paper presents categorization of notions and characteristics of the entropy of a discrete random variable. In addition to Shannon’s entropy, the Rényi’s and Tsallis entropies were applied for studies on the properties of distributions in case of probabilities of the random variables. The notion of entropy stemming from thermodynamics found application in many fields of sciences. Shannon’s entropy was defined on the grounds of the information theory, the Rényi’s entropy is the result of generalization of the Kolmogorov-Nagumo average while the Tsallis entropy is a certain function of Rényi’s entropy. The present paper unifies these approaches by presenting one general model of concentration measure that applies Rényi’s entropy.
Modelling of CO2 Sequestration in Deep Saline Aquifer Reservoir using Surface Evolver Software
Authors: Kumar Pradeep
Published: January 2024

A strategy to mitigate CO2 concentration in the atmosphere is injection of supercritical CO2 in porous sedimentary medium filled with saline water where CO2 gets trapped in the pores. Sequestration is resultant of two processes, drainage and imbibition in accordance with capillary law. Simulation of the pore-scale trapping has been performed on reservoir scale. A simple model reservoir consisting of 1000 tetrahedral subunits was constructed. Using Surface Evolver software, pore volueach subunit. The CO2 pressure and liquid saturation curves of the reservoir displayed hysteretic character, indicating that the evolution of the system is pathway-dependent. The simulated curves illustrate the pathway dependency of the residual gas saturation, an important parameter controlling the amount of CO2 stored in the reservoir, hence the efficiency of the CO2 storage. Our study also shows the existence of critical thresholds in terms of in/out gassing during the drainage or imbibition processes
GEOCHEMISTRY AND ORIGIN OF BANDED ORE OF MANGANESE BELT, EASTERN CARPATHIANS, ROMANIA.
Authors: HÎRTOPANU PAULINA
Published: January 2024

The Manganese Belt has a great mineralogical diversity and rarity contining more than 350 minerals and mineral varieties, of which 182 are new for Romania, being one of the most complex deposit in the world. The manganese ores are of carbonate-silicate type with a few oxides and sulfides. The chemical composition of many manganese carbonates, silicates, and oxides have high Mn/Fe ratios. The all manganese ores/manganiferous rocks have well-developed laminations/bandings, that appeared in hand samples and thin sections, representing distinct lithologies/petrographic types. The folowing types were established: metachert, quartzite with alkali pyroxenes and amphiboles, tephroite, Mn-humites, spessartine, pyroxmangite, rhodonite, mangancummingtonite, nambulite and natronambulite, pyrosmalte, and vein type (bannisterite, ganophyllite, and stilplomelane), all host by Tulgheş Series 1 (TG1) rocks. Each type was geochemical analysed. All lithology types show low concentrations of Ni, Co, Cu, Zn, U, Th, and REE trace elements, being similar to the trace element concentrations reported from sediments which are forming in hydrothermally active regions on the present sea floor. The metachert shows similar, but in low concentrations of trace elements, as the type ore. The metachert and manganese ore have high Li concentrations as trace element. The association of the manganiferous lithologies with metachert and meta-igneous rocks of TG1 is consistent with deposition of the original sediments in a rifting envronment, such as a back-arc basin. The current tectonic and structural setting of Mn ore correspond to their development and evolution in a subduction/rift zone, a narrow and long active paleotrench area, reflected in their line development as belt.
Proiectul lui C. Rădulescu-Motru de fundamentare a psihologiei ca știință a naturii
Authors:   Institutul de Filosofie și Psihologie „C. Rădulescu-Motru” al Academiei Române, Mamulea Mona
Published: January 2024

In his early writings, Rădulescu-Motru acknowledged as a valuable gain the fact that psychology had emancipated itself from the tutelage of metaphysics. However, he believed that this progress could not lead to a scientific psychology unless its outcomes were integrated into the broader scientific understanding of nature. In the following, I will discuss Rădulescu-Motru’s ideas concerning the founding of psychology as a natural science. His project essentially involves three directions: (1) conceptual reconsideration, (2) uniformization, and (3) regulation of the soul. I will also show that throughout this process, Rădulescu-Motru remained committed to methodological naturalism.
C. Rădulescu-Motru and the pursuit of a new science of the soul
Authors:   Universitatea „Al. I. Cuza”, Iași, Lupașcu Constantin C.
Published: January 2024

The following study presents a concise historical overview of natural philosophy, examining the interpretations of the human psyche and their development up until the contemporary era. The presentation focuses on some of the main theories regarding the nature and functions of the mind, aiming to contrast them with one of the unfulfilled intellectual projects of the Romanian polymath C. Rădulescu-Motru. Specifically, his project aimed to establish a philosophical system addressing the intricacies of the human soul in the context of the scientific advances considered modern at the time– a system he referred to as the new science of the soul. His objective was to provide a comprehensive perspective encompassing all areas of knowledge in order to mitigate their tendency towards determinism, mechanism and biologism, which were spreading from the direction of the natural science.
Impactul culturii și civilizației moderne asupra condiției omului contemporan (Tragedia omului în cultura modernă)
Authors:   Universitatea Ecologică din București, Stroe Constantin
Published: January 2024

Holder of two degrees – one in religious studies (1930) and the other in philosophy (1947), both obtained from the University of Bucharest –, as well as author of significant works covering the two aforementioned fields, Constantin C. Pavel, professor and theologian, imposed himself as a remarkable personality in Romanian religious and philosophical culture. He is well-known for his moral philosophy, referencing human nature and condition, and expertly expressing his opinion on the disastrous impact that modern culture and its civilizational components have on human beings. The current study brings to attention the aspects raised by this approach, specifically the human–culture–religion triad, from the positions of the Orthodox Christian doctrine embraced by Constantin C. Pavel in Tragedia omului în cultura modernă [The tragedy of man in modern culture].
Magnetic Properties of M-Type Hexagonal Ferrite: Mechanical Applications
Authors: Ul Nissa Laraib , Amir Rabia , Noreen Misbah , Karim Saidul , Shahzad Muhammad Adeel , Irfan Muhammad , Yasir Muhammad
Published: January 2024

As the information era continues to advance at a rapid pace, M-type strontium ferrite and other magnetic materials are finding more and more traditional uses. Numerous industries rely on it as a permanent magnet material because of its inexpensive cost, ease of preparation, and outstanding overall performance in areas including electronics, national defense, and communication. In this paper, we investigate some the magnetoelectric coupling properties at room temperature by solid phase method and sol-gel method. The phase structure was determined using an X-ray diffractometer, and the samples were all single-phase polycrystalline with a spatial group of P63/mmc. Observing the surface morphology using field emission scanning electron microscopy, it was found that the composition distribution of the samples prepared by solid-phase method was uneven and there was a "scandium rich phase". The samples prepared by the sol gel method have uniform composition distribution, hexagonal grain shape, and grain size of about 3-5 μ M. The magnetic properties of the samples prepared by the sol gel method and the solid phase method were studied, respectively. The results showed that the phase transition occurred in the solid phase method at about 250K, and the hysteresis loop at room temperature did not show the magnetoelectric coupling behavior. The magnetic phase transition of the sample prepared by the sol gel method occurred near 330K. Combined with the research on the hysteresis loops of the temperature above and below this phase transition point, it shows that this phase transition corresponds to the change of the ferromagnetic to the conical magnetic structure. The similar relationship between magnetic capacitance and magnetization intensity with magnetic field indicates that this conical magnetic structure can induce ferroelectric polarization, which can be understood based on the inverse Dzyaloshinskii-Moriya model.
AI and Digital Twin Transforms in the Construction of Precision Medical Model: Healthcare Management in Smart Cities
Authors: Ahmed Atique , Shoukat Khadija , Muneeb Muhammad Ahmad , All Qasem Doaa Abdo Othman , Shahzad Muhammad Adeel , Nissa Laraib Ul , Amir Rabia , Zubair Muhammad , Younas Muhammad Waqas , Ali Asad
Published: January 2024

In recent years, the integration of artificial intelligence (AI) and digital twin (DT) is driving a new revolution in the healthcare field. Precision medical methods can utilize the complex computing techniques and models of AI, combined with various genetic and non-genetic data, to enable the system to reason and learn under the drive of data and algorithms, assisting clinical doctors and researchers in making more accurate related decisions. Research has shown that AI and DT has shown enormous technological application space in genomics, clinical cancer treatment, molecular imaging, and other fields, but it also faces potential challenges such as system bias, correlation limitations, algorithm black boxes, and unfairness. This requires the use of AI and DT transformations to build a precision medical intelligent system, which can update, capture, and study real-world data in real-time and simulate in DT. This study proposes that real-world data should be constructed from information system data and medical knowledge data from various hospitals, combined with the roles of real-world evidence (RWE), randomized clinical trial (RCT), genetic research, and AI technology in precision medicine, to innovatively design a precision medical smart system in the social 5.0 smart city. This work also proposes the structure and operating standards of the smart system, providing innovative ideas and contributions for the future construction of precision medical smart systems in society.
A Study of Bacteriological Profile of Bacterial Isolates in Sputum Samples in Azadi Teaching Hospital in Duhok City
Authors: Algurairy Alaa' Turki Monawer
Published: January 2024

The objective of this current study is to examine the bacteriological profile of microorganisms isolated in sputum samples collected from the patients in the Azadi Teaching Hospital in Duhok City. The current cross-sectional observational study was carried out in the Laboratory of Microbiology, Department of the Basic Science, College of Nursing at the University of Duhok, Kurdistan region, Iraq. A total of 150 patients with clinically verified bacterial infections were included in the study using a gram-staining and routine sampling procedure. Microscopic examination of the gram-stained sputum smears was done to assess the presence of epithelial cells, pus cells, or organisms. Consequently, 83 bacterial samples yielded positive results that indicated the presence of bacterial growth, while the remaining samples 67 did not exhibit any bacterial growth or normal flora. On assessing the organisms isolated from the study subjects, it was observed that out of 150 processed sputum samples, 44.7% (n=67) were non-bacterial samples and 55.3% (n=83) were pathogenic bacterial samples. It was seen that the most common isolated organism was Klebsiella pneumoniae in (44.6%; 37/83), followed by Pseudomonas aeruginosa in (35%; 29/83), and then Escherichia coli in (20.4%; 17/83), were the most frequently isolated microorganisms from sputum samples of patients with upper or lower respiratory infections. The current study comes to the conclusion that in order to obtain lower respiratory tract infection samples from subjects, high-quality sputum must be obtained, and initial sputum screening should be carried out.
Politics in Fisheries Management: Consultation with Fishing Communities in the Indian Ocean, Tanzania
Authors: Bulengela Gideon
Published: January 2024

Fisheries resources are declining globally. The fishers around the globe have been largely blamed for the decline. The aim of this study was to investigate the influence of politics on fisheries management in Tanzania. To achieve this, a qualitative study was conducted in three fishing communities along the Indian Ocean. A total of forty six interviews was conducted. Additionally, six focus group discussions were conducted. Data were analyzed using a content analysis approach. Findings indicate that, politicians influenced sustainable fisheries management efforts in the study areas. This study concludes that, fishers should not be blamed for failures of sustainable fisheries management initiatives; instead, researchers and fisheries managers need to acknowledge and address several forces that shape and influence fishing practices including politics.
Wie es geht: Rechte klären · Verträge mit Verlagen verhandeln · Zweitveröffentlichungsrecht nutzen
Authors: Kreutzer Till
Published: January 2024

Wie funktioniert die Einholung vom Nutzungsrechten bei fremden Inhalten? Was steht in meinem Verlagsvertrag? Und wie war das noch gleich mit dem Zweitveröffentlichkeitsrecht? iRights.info liefert Antworten zu wichtigen Fragen beim wissenschaftlichen Publizieren – kompakt und praxisnah.
Conceptualization of index methodology for measuring manager's satisfaction with their job, private life and work/life balance
Authors: Mladenović Milica , Krstić Bojan , Simonović Zoran
Published: January 2024

In the era of knowledge economy, company's competitive advantage is mostly created by skills and knowledge of its employees, especially managers as the most significant segment of company's human intellectual capital. The subject of this paper is manager's work/life balance and possibility of its measurement. Balanced and satisfied managers represent a good foundation for achieving company's goals. The paper will present certain subjective factors and company factors that can affect manager's work/life balance. Within these factors, various practices and benefits for establishing manager's work/life balance can be distinguished, depending on whether they are created by companies and offered to their managers, or they are designed and implemented by managers themselves outside the company. The purpose of this paper is presenting the conceptual model of interdependence of manager's job satisfaction, manager's private life satisfaction and manager's work/life balance satisfaction, which includes dimensions of each of these types of manager's satisfaction that managers can assess through a questionnaire. Based on this model and managers' grades, the result of this paper is reflected in the created index methodology for calculating the values of indices of the mentioned types of manager's satisfaction, which can be applied at the level of the individual manager as well as at the level of the company, and it can also be used for comparing the values of determined satisfaction indices by managers, by years and between companies.
Early doctrine of budgetary incrementalism in the theory of Charles Lindblom and Aaron Wildavsky
Authors: Rapajić Milan , Lapčević Milivoje , Miladinović Violeta
Published: January 2024

Despite numerous attempts of contemporary financial executives to enhance the national process of public budgeting with innovative solutions, the model of traditional, incremental budgeting still withstands as a primary form of budgetary technicism. The crucial contribution to describing and radical popularization of incremental ratio in the field of public budgeting was made by American scientists Aaron Wildavsky and Charles Lindblom who are considered to be the pioneers of early doctrine of budgetary incrementalism. Charles Lindblom approached the phenomenon of incremental decision-making in the context of wider social scene, advocating the advantages of marginal changes of public policy decisions in all spheres of decision-making as opposite to radical deviation from formerly adopted course of action. On the other side, Aaron Wildavsky explained with great precision the incremental ratio in decision making process in the field of public budgeting, that is annual budget decision making. According to Wildavsky, we should not pose the question how the process of public budgeting should look like ("what is a good budget?"), but we should only describe this process as it essentially is, or only could be. This leads us to the conclusion that incrementality, in the theory of early incrementalism, is viewed as an innate characteristic of budgeting process despite various reform initiatives.
Economic analysis of the Solow model of economic growth
Authors: Krstić Dalibor , Braković Bojan , Božović Ivan
Published: January 2024

Economic growth is one of the most common topics of discussion in economic history. To date, many theorists who explain the factors that affect the generation of economic growth have differentiated themselves. Although the accounting of development dealing with production functions identifies the sources of economic growth, it does not explain why capital accumulation, changes in the ratio of factors of production or productivity occur. Using Solov's growth model, which explains economic growth by the production function in which it shows the relationship between capital accumulation, savings and capital growth, we come to the answer to these questions.
Crisis management and communication in public relations
Authors: Lazarević Sofija
Published: January 2024

Social crises in various forms have become a modern day challenge. Dealing with its consequences can best be seen in the political, economic and security sectors. In earlier periods, public relations was considered to be the most important for large corporations in their positioning on the market. However , today, when the world is facing a small and intertwining crisis (World Economic Crisis, Migrant Crisis, Brexit, Covid 19 Crisis, and the last Ukrain-Russian Crisis) it is clear that governments and state bodies must be stable carriers of crisis response, precisely because the institutions are the ones that guarantee stability of the state. In cases of inadequate response to the crisis situation, the trust of the citizens in the institution that is the bearer of the response to the crisis is shaken, which further reflects on the reputation of the institution itself, and then od the stability of the state. Therefore , every state body must be ready for decision- making in crisis situations. This text will present the recommendations that the crisis team must adopt in order to adequately respond to crisis situation. In addition to the above, the example of the reaction of the Government of the Republic of Serbia to the crisis caused by the COVID 19 virus will be analyzed, in order to position further desirable behavior of the institutions in times of crisis.
Corruption and trafficking in human beings: (Un)explored nexus
Authors: Pajić Nataša
Published: January 2024

The subject of this article is the relationship between corruption and human trafficking, more specifically, the impact of corruption on the emergence and spread of trafficking in human beings. This paper aims to systematize the findings of existing theoretical and empirical studies that have examined the connection between corruption and trafficking in human beings. As the primary research method, the author employs a literature review. Scientific papers that have addressed the link between the key concepts were analyzed. Findings indicate that corruption is one of the strongest predictors of human trafficking in the countries of origin, as well as the most significant factor facilitating the process of human trafficking and enabling impunity for perpetrators of this criminal act. Based on insights from the existing academic literature, we can conclude that the nexus between corruption and trafficking in human beings remains insufficiently explored.
Branko Popović as a contemporary and critic of Belgrade's architecture scene
Authors: Dukić Anđela
Published: January 2024

The activity of Branko Popović is primarily defined in historiography through valorizations of his artistic oeuvre and his role as an art critic, one that he continuously undertook during the first half of the 20th century. Given that Popović's contributions to architectural criticism and the interpretation of contemporary architectural phenomena and problems have often lain outside the main scope of particular research endeavours, instead often being presented in summarial form within monographs and anthologies, there is an acute need for elaboration of this area of his outputs. Popović primarily received his higher education at the Technical Faculty in Belgrade, where he later held the role of professor of history of art and architecture, and during the Second World War he held the position of Dean. The aim of this work is to present, through the review and analysis of articles published in pre-war and inter-war periodicals, another aspect of Popović's interpretations and criticisms, based on perceptions of and participations in contemporary events in the field of architecture, which would complete his contribution to the shaping of artistic thought.
Environmental activism and pro-environmental behaviour in Serbia: Determinants and relationships with subjective well-being
Authors: Popov Boris , Zorić Jovana , Bodroža Bojana
Published: January 2024

Environmentally significant behaviours, such as pro-environmental behaviour and environmental activism, have remained relatively ill-defined and poorly integrated to date. The relationship between environmental activism and subjective well-being is particularly unclear. Therefore, the aim of this research is to determine whether some socio-demographic characteristics, such as gender, age and level of education, predict pro-environmental behaviour and environmental activism, as well as whether these behaviours have some effect on subjective well-being. A total of 354 respondents (222 female; 62.7%) filled out the Environmental Responsibility Feelings Scale, the Ecological Behaviour Scale, and the Environmental Activism Scale. Utilizing a correlational study design, path analysis revealed that older respondents and those with a higher level of education exhibit more pro-environmental behaviour and environmental activism. The results also suggest that the feeling of responsibility towards the environment significantly predicts the level of environmental activism, but not pro-environmental behaviour. Gender did not show a significant effect on either pro-environmental behaviour or environmental activism. Finally, it was found that environmentally significant behaviours in this research were not related to subjective well-being. Possible explanations of the obtained results are offered, as well as guidelines for future research into these phenomena.
Compatibility with Fundamental Freedoms of a Municipal Surcharge Distinguishing between Residents and Non-Residents for the Purposes of the Applicable Rate – Opinion Statement ECJ-TF 4/2023 on the Decision of the EFTA Court of 4 July 2023 in RS (Case E-11/22)
Authors: Garcia Prats F.A. , Haslehner W. , Kemmeren E. , Kofler G. , Lang M. , Nogueira J.F. Pinto , HJI Panayi C. , Raventós-Calvo S. , Richelle I. , Rust A.
Published: January 2024

In this CFE Opinion Statement, submitted to the EU Institutions in December 2023, the CFE ECJ Task Force comments on the CJEU’s decision of 4 July 2023 in RS (Case E-11/22), which addressed whether or not municipal surcharges are compatible with the fundamental freedoms.
Pembangunan dan Pelatihan Website Profil Desa pada Desa Kiritana
Authors: Talakua Alfrian , Rada Yustina
Published: January 2024

Desa Kiritana merupakan desa yang terletak di kecamatan kambera Kabupaten sumba timur nusa Tenggara timur yang memiliki berbagai potensi desa melalui sumber daya alam berupa pertanian dan lokasi objek wisata. Hal ini perlu dikembangkan dan dipromosikan guna mengembangkan desa kedepaan. Pemerintah desa kiritana memerlukan bantuan untuk mengembangkan sebuah media digital sebagai sarana informasi bagi Masyarakat untuk itu pemerintah desa dan akademisi dari Universitas Kristen Wira Wacana Sumba terkhususnya Program Studi Teknik informatika bekerjasama untuk membangun website desa guna menunjang pekembangan desa menuju desa digital, hal inipun tertuang pada Undang-Undang Nomor 6 Tahun 2014 Tentang Desa. Pemberdayaan Teknologi Informasi akan sangat membantu proses kinerja pemerintah desa dalam membagikan informasi terkait desa dan membantu memproses atau mengelolah data desa yang dapat disajikan sebagai informasi, namun terkait dengan hal tersebut aparat desa belum memilki Sumber daya untuk membangun sarana tersebut, sehingga dengan dilaksanakan PkM dapat membantu pemeritah desa kedepan untuk mempromosikan desa dan juga dapat membantu pemerintah desa dalam pengarsipan dan pengolahan data. PkM telah dilaksanakan selama 2 bulan dimulai dari pembuatan website hingga pada pelatihan dan pendampingan aparatur desa untuk mengatur dan mengelolah website desa yang telah dibangun. Hasil dari PkM ini sangat membantu Masyarakat desa kiritana harapan dari pemerintah desa untuk terus dilakukan kolaborasi dengan akademisi guna membangun desa kiritana kedepan.
Exploring Unidentified Aerospace Phenomena Through Instrumented Field Studies: Historical Insights, Current Challenges, and Future Directions
Authors: Ailleris Philippe
Published: January 2024

The study of Unidentified Aerospace Phenomena (UAP) requires a shift from a historical, narrative-based approach to a scientific and technology-based study. To conduct unbiased and agnostic research on UAPs, rigorous scientific study is necessary, including the collection of hard data to support credible explanations or scientifically prove the existence of unknown phenomena. Obtaining reliable and valid data requires instrumented observations, including multi-wavelength and multi-mode sensors (e.g., optical, radar, infrared). We present herein an overview of the benefits as well as the strategic and tactical considerations of instrumented field studies, highlighting common limitations and shortcomings with the objective of contributing to the development of future projects. We provide an overview of some past and current UAP military and civilian projects and analyze a timetable of instrumented projects spanning the years 1950-2023, encompassing contributions from both citizen science and professional/academic science. In conclusion, this paper reflects on how UAP field experiments might look going forward. Newer technologies like digital cameras, scientific instruments, computing, big data analytics, artificial intelligence, and satellite imagery are becoming more advanced and cost-effective. This is leading to the growth and progress of technical field studies, complementing local projects with global-scale investigations. Researchers can enhance their chances of success by adopting a more disciplined approach and exploring innovative avenues. Collaboration, transparency, and standardization in data collection and analysis are crucial, while also acknowledging the complex nature of the UAP phenomenon.
Development, Dissemination, and Revision of Good Scientific Practice for Research on UAP
Authors: Ammon Danny
Published: January 2024

Research on UAP experiences, especially in the form of a single case study or investigation, is primarily conducted by lay or citizen scientists worldwide. There is a need for responsible and methodically justified research to be established to receive verifiable, comparable work results and to ensure ethically conscientious interactions with other researchers and experience reporters. In this article, principles of good scientific practice for research on UAP in Germany are presented. In part, these principles are derived from existing professional norms, but they are further specified for UAP research. Predecessors of the principles are identified; then the process of their development and different stages of review are described. Furthermore, the application of the principles and their revision process are discussed. The paper concludes with the presentation of the research principles in the current version. In conclusion, the establishment and application of such principles can improve the quality of research conducted by volunteering individuals or non-profit organizations and thus generate better data on UAP.