bluuebunny/crossref_metadata_2025 huggingface dataset:
Treatment at an Inexperienced Center Suggests Worse Prognosis of Metastatic Germ Cell Tumors
Authors: YAEGASHI HIROSHI , IZUMI KOUJI , KADOMOTO SUGURU , IWAMOTO HIROAKI , IIJIMA MASASHI , KAWAGUCHI SHOHEI , NOHARA TAKAHIRO , SHIGEHARA KAZUYOSHI , KADONO YOSHIFUMI , MIZOKAMI ATSUSHI
Published: November 2021

Background/Aim: We evaluated the clinical outcomes of patients with metastatic germ cell tumors (GCT) treated at our hospital, which belongs to a regional cancer center. Patients and Methods: Data pertaining to patients with metastatic GCT were obtained between April 2007-October 2017 and was retrospectively analyzed. Key outcome measures included objective response rates and survival rates.Results: All 42 patients received chemotherapy [complete response: eight (19.0%); partial response: 21 (50.0%); stable disease (SD): nine (21.4%); progressive disease: four patients (9.5%)]. Post-chemotherapeutic surgery was performed for seven out of 21 cases of partial response and two out of nine of stable disease. The 5-year survival rates of patients with good, intermediate and poor prognosis (International Germ Cell Consensus Classification) were 100%, 100%, and 71.4%, respectively. Patients who received induction chemotherapy at other hospitals had significantly poorer prognosis than those at our hospital (p=0.0043). Conclusion: Patients with metastatic GCT should preferably receive chemotherapy at an experienced institution.
A Treatment-free Interval Allowed by Ponatinib as Fourth-line Therapy
Authors: BULLA ANNA , MARKOVIC UROS , BELLOFIORE CLAUDIA , STELLA STEFANIA , CONTICELLO CONCETTA , DI RAIMONDO FRANCESCO , STAGNO FABIO
Published: November 2021

Background: The third-generation tyrosine kinase inhibitor ponatinib has demonstrated high clinical efficacy in the setting of patients with resistant chronic phase chronic myeloid leukemia (CML), also inducing deep molecular responses. However, ponatinib-related cardiovascular toxicities make management challenging, especially of those patients with CML with previous cardiovascular comorbidities. Case Report: We report on the efficacy of ponatinib treatment used as fourth-line therapy in a 55-year-old woman affected by significant comorbidities (mainly cardiovascular) present before the diagnosis of CML. Ponatinib therapy induced a rapid and excellent clinical response, with the achievement of a durable deep molecular response that allowed us to propose a strategy of treatment discontinuation in order to reduce drug-related toxicities. Conclusion: A strategy of a treatment-free interval might represent a useful clinical tool in those patients with CML who achieve a durable deep molecular response but are also affected by significant comorbidities in order to minimize the risk of ponatinib-related toxicities.
Cannabidiol Μay Prolong Survival in Patients With Glioblastoma Multiforme
Authors: LIKAR RUDOLF , KOESTENBERGER MARKUS , STUTSCHNIG MARTIN , NAHLER GERHARD
Published: November 2021

Background: Glioblastoma multiforme (GBM) is a relatively rare type of brain tumour with an incidence rate around 6 per 100,000. Even with the widely practiced combination of radiotherapy with adjuvant temozolomide, the median overall survival remains low with just 13.5 to 16 months after diagnosis. Patients and Methods: We retrospectively reviewed the survival of a cohort of 15 consecutive, unselected patients with histopathologically confirmed glioblastoma multiforme (GBM) who received CBD (400 to 600 mg orally per day) in addition to standard therapy (maximum resection of the tumour followed by radio-chemotherapy). Results: Of 15 patients, seven (46.7%) are now living for at least 24 months, and four (26.7%) for at least 36 months. This is more than twice as long as has been previously reported in the literature. The mean overall survival is currently 24.2 months (median 21 months). Conclusion: CBD is a well supported co-medication and seems to prolong the survival of patients with glioblastoma multiforme.
Common Malignancies During Pregnancy: A Comprehensive Review
Authors: KALAMPOKAS EMMANOUIL , VLAHOS NIKOLAOS , KALAMPOKAS THEODOROS , GURUMURTHY MAHALAKSHMI
Published: November 2021

Malignant disease complicates pregnancy in up to 1 per 1,000-2,000 cases. Pregnancy itself does not constitute a predisposing factor for malignancy. Management and treatment of patients suffering from a malignancy during pregnancy still represents a challenge in everyday clinical practice. Recent advances in imaging, diagnostic and overall treatment modalities have tailored the management of patients, specifically those who wish to maintain the pregnancy. The aim of this review was to provide clinicians with concise information on the management of the most common malignancies during pregnancy. We performed a review of the current literature including review articles, original research articles and guidelines, which are used for the management of the most common malignancies during pregnancy. Breast, cervical and ovarian malignant tumours are the most common during pregnancy. However, the overall outcome and survival per stage for these cancers do not appear to be influenced by pregnancy. Ethical, emotional and treatment dilemmas may be encountered during treatment planning. Individualization of treatment planning should be made by a multidisciplinary team but the final decision rests with the parents.
Impact of Hypertension on Early Renal Dysfunction in Japanese Prostate Cancer Patients Treated With Androgen Deprivation Therapy
Authors: MASUDA HIROSHI , SUGIURA MASAHIRO , HOU KYOKUSIN , ARAKI KAZUHIRO , KOJIMA SATOKO , NAYA YUKIO
Published: November 2021

Background/Aim: Recently, it was reported that the use of androgen deprivation therapy (ADT) is significantly associated with an increased risk of acute kidney injury (AKI) in patients with newly diagnosed non-metastatic prostate cancer. This study aimed to investigate the incidence of early renal dysfunction in Japanese prostate cancer patients receiving ADT and the factors associated with it. Patients and Methods: A total of 135 patients who had been pathologically diagnosed with prostate cancer and had received ADT for at least 6 months were eligible for study inclusion. The estimated glomerular filtration rate (eGFR) before treatment, and at 1, 3, and 6 months of ADT were evaluated retrospectively. We assessed renal function using eGFR and investigated the rate of change in the eGFR (ΔeGFR) during ADT. Univariate and multivariate logistic analyses were carried out to identify clinical factors that were significantly associated with renal dysfunction after 6 months ADT. Results: A total of 110 cases were evaluated in this study. The incidence of renal dysfunction after 6 months ADT was 63% (69/110). The mean ΔeGFR after 1, 3, and 6 months of ADT were –0.6%, –3.1% and –1.7%, respectively (p<0.001). Multivariate analysis showed that renal dysfunction after 3 months of ADT and hypertension were independent risk factors for renal dysfunction after 6 months ADT. Conclusion: Renal dysfunction occurs from 1 month of ADT and hypertensive prostate cancer patients receiving ADT are at high risk of developing renal dysfunction, and that such patients should be treated very carefully. Therefore, patients that are started on ADT should undergo periodic prostate-specific antigen, renal function, and urinary salt intake examinations.
Absolute Lymphocyte Counts After Lenalidomide Initiation may Predict the Prognosis of Patients With Relapsed or Refractory Multiple Myeloma
Authors: NAKAGAWA MASARU , IRIYAMA NORIYOSHI , ISHIKAWA TAKUTO , MIURA KATSUHIRO , UCHINO YOSHIHITO , TAKAHASHI HIROMICHI , HAMADA TAKASHI , IIZUKA KAZUHIDE , KOIKE TAKASHI , KURIHARA KAZUYA , NAKAYAMA TOMOHIRO , HATTA YOSHIHIRO , TAKEI MASAMI
Published: November 2021

Background/Aim: We assessed the prognosis of patients with refractory or relapsed multiple myeloma (RRMM) by focusing on the change in absolute lymphocyte counts (ALCs) after lenalidomide and dexamethasone (Ld) initiation. Patients and Methods: In total, 72 patients with RRMM were treated with Ld. ALCs were evaluated before treatment and at 1, 2, and 3 months after Ld initiation. The median ALCs in the entire cohort before and at 1, 2, 3 months after Ld initiation were 1,131, 1,059, 1,222, and 1,162/μl, respectively. Results: ALCs before Ld initiation did not affect time to next treatment (TNT) or overall survival (OS). However, the patients with ALCs equal to or greater than the median at 3 months showed relatively better TNT than those with lower lymphocyte counts, with a significant difference. OS was also significantly longer in patients with higher ALCs. Conclusion: Immunomodulation by lenalidomide may improve prognosis in patients with RRMM.
A Blockchain-Based Dynamic Consent Architecture to Support Clinical Genomic Data Sharing (ConsentChain): Proof-of-Concept Study
Authors: Albalwy Faisal , Brass Andrew , Davies Angela
Published: November 2021

Background

In clinical genomics, sharing of rare genetic disease information between genetic databases and laboratories is essential to determine the pathogenic significance of variants to enable the diagnosis of rare genetic diseases. Significant concerns regarding data governance and security have reduced this sharing in practice. Blockchain could provide a secure method for sharing genomic data between involved parties and thus help overcome some of these issues.

Objective

This study aims to contribute to the growing knowledge of the potential role of blockchain technology in supporting the sharing of clinical genomic data by describing blockchain-based dynamic consent architecture to support clinical genomic data sharing and provide a proof-of-concept implementation, called ConsentChain, for the architecture to explore its performance.

Methods

The ConsentChain requirements were captured from a patient forum to identify security and consent concerns. The ConsentChain was developed on the Ethereum platform, in which smart contracts were used to model the actions of patients, who may provide or withdraw consent to share their data; the data creator, who collects and stores patient data; and the data requester, who needs to query and access the patient data. A detailed analysis was undertaken of the ConsentChain performance as a function of the number of transactions processed by the system.

Results

We describe ConsentChain, a blockchain-based system that provides a web portal interface to support clinical genomic sharing. ConsentChain allows patients to grant or withdraw data requester access and allows data requesters to query and submit access to data stored in a secure off-chain database. We also developed an ontology model to represent patient consent elements into machine-readable codes to automate the consent and data access processes.

Conclusions

Blockchains and smart contracts can provide an efficient and scalable mechanism to support dynamic consent functionality and address some of the barriers that inhibit genomic data sharing. However, they are not a complete answer, and a number of issues still need to be addressed before such systems can be deployed in practice, particularly in relation to verifying user credentials.
Effectiveness of a Walking Football Program for Middle-Aged and Older Men With Type 2 Diabetes: Protocol for a Randomized Controlled Trial
Authors: Barbosa Ana , Brito João , Figueiredo Pedro , Seabra André , Mendes Romeu
Published: November 2021

Background

Studies on walking football have found positive effects on health; however, there are still several research gaps when applying walking football programs for patients with type 2 diabetes.

Objective

This study aims to test the effectiveness of a walking football exercise program on glycemic control and cardiovascular risk factors in middle-aged and older men with type 2 diabetes.

Methods

The study will be run as a randomized controlled trial with a 6-month duration in Portugal. Eligible participants will be randomized using a 1:1 ratio for intervention or control groups and compared using an intention-to-treat analysis. The intervention will consist of a walking football exercise program. The control group will continue with usual care in primary health care units. The primary outcome will be the mean difference in glycated hemoglobin between intervention and control groups after 6 months. Secondary outcomes include the mean differences in fasting blood glucose, total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglycerides, systolic and diastolic blood pressure, body mass index, waist circumference, fat-free mass, and fat mass. Additionally, secondary outcomes include the incidence of exercise-related injuries and adverse events and the walking football exercise program’s cost-utility.

Results

The study protocol is being prepared to be submitted to the Health Ethics Committee of the Northern Regional Health Administration, Portugal. After approval, participant recruitment will start in primary health care units in Porto's metropolitan area by family medicine doctors.

Conclusions

Walking football might have the potential to be effective in improving glycemic control and cardiovascular risk factors, with a low rate of exercise-related injuries and adverse events and a good cost-utility ratio. Therefore, walking football may be a sustainable intervention strategy for type 2 diabetes management.

International Registered Report Identifier (IRRID)

PRR1-10.2196/28554
A Mobile App to Enhance Behavioral Activation Treatment for Substance Use Disorder: App Design, Use, and Integration Into Treatment in the Context of a Randomized Controlled Trial (Preprint)
Authors: Paquette Catherine E , Rubalcava Dillon T , Chen Yun , Anand Deepika , Daughters Stacey B
Published: November 2021

BACKGROUND

Group-based formats typically used in low-resource substance use disorder (SUD) treatment settings result in little individual attention to help reinforce and guide skill use, which may contribute to poor posttreatment outcomes. Smartphone apps offer a convenient, user-friendly, and cost-effective tool that can extend the reach of effective SUD treatments. A smartphone app was developed and integrated into a group-based, brief behavioral activation (BA) treatment for SUD to increase engagement in treatment skills outside clinician-administered sessions.

OBJECTIVE

This study aims to describe the features of the app and its use and integration into treatment, report the participants’ self-reported feasibility and acceptability of the app, and discuss challenges and provide recommendations for future smartphone app integration into behavioral treatments for SUD.

METHODS

A total of 56 individuals recruited from intensive outpatient SUD treatment received a smartphone-enhanced BA treatment, the Life Enhancement Treatment for Substance Use. Self-reported weekly app use and reasons for nonuse were assessed at posttreatment and at 1- and 3-month follow-ups. In addition, 2-tailed t tests and chi-square tests compared the self-reported use of each app component and overall app use over time.

RESULTS

Participant feedback suggested that the integration of the smartphone app into the Life Enhancement Treatment for Substance Use was feasible and well accepted, and participants found the app useful for planning value-based activities outside of sessions. Self-reported app engagement decreased over the follow-up period: 72% (39/54) of participants reported using the app at posttreatment, decreasing to 69% (37/54) at the 1-month follow-up and 37% (20/54) at the 3-month follow-up. Participants reported forgetting to use the app as a primary reason for nonuse.

CONCLUSIONS

This study provides support for the feasibility and acceptability of smartphone-enhanced BA treatment, offering promise for future research testing the integration of technology into SUD treatment. Design decisions may help streamline smartphone integration into treatment, for example, allowing participants to download the treatment app on their own phones or use a low-cost study smartphone (or offering both options). Long-term app engagement may be increased via built-in reminders, alerts, and in-app messages.

CLINICALTRIAL

ClinicalTrials.gov NCT02707887; https://clinicaltrials.gov/ct2/show/study/NCT02707887
Effectiveness of a Walking Football Program for Middle-Aged and Older Men With Type 2 Diabetes: Protocol for a Randomized Controlled Trial (Preprint)
Authors: Barbosa Ana , Brito João , Figueiredo Pedro , Seabra André , Mendes Romeu
Published: November 2021

BACKGROUND

Studies on walking football have found positive effects on health; however, there are still several research gaps when applying walking football programs for patients with type 2 diabetes.

OBJECTIVE

This study aims to test the effectiveness of a walking football exercise program on glycemic control and cardiovascular risk factors in middle-aged and older men with type 2 diabetes.

METHODS

The study will be run as a randomized controlled trial with a 6-month duration in Portugal. Eligible participants will be randomized using a 1:1 ratio for intervention or control groups and compared using an intention-to-treat analysis. The intervention will consist of a walking football exercise program. The control group will continue with usual care in primary health care units. The primary outcome will be the mean difference in glycated hemoglobin between intervention and control groups after 6 months. Secondary outcomes include the mean differences in fasting blood glucose, total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglycerides, systolic and diastolic blood pressure, body mass index, waist circumference, fat-free mass, and fat mass. Additionally, secondary outcomes include the incidence of exercise-related injuries and adverse events and the walking football exercise program’s cost-utility.

RESULTS

The study protocol is being prepared to be submitted to the Health Ethics Committee of the Northern Regional Health Administration, Portugal. After approval, participant recruitment will start in primary health care units in Porto's metropolitan area by family medicine doctors.

CONCLUSIONS

Walking football might have the potential to be effective in improving glycemic control and cardiovascular risk factors, with a low rate of exercise-related injuries and adverse events and a good cost-utility ratio. Therefore, walking football may be a sustainable intervention strategy for type 2 diabetes management.

INTERNATIONAL REGISTERED REPORT

PRR1-10.2196/28554
Data-driven prediction for acute exacerbations of chronic obstructive pulmonary disease complicated with type 2 respiratory failure (Preprint)
Authors: Wang Huilai , Zhou Yang , Gong Jun , Wang Haolin , Liao Yang , Xiang Tianyu
Published: November 2021

BACKGROUND

Type 2 respiratory failure(T2RF) is one of the main causes of death in patients with acute exacerbations of chronic obstructive pulmonary disease (AECOPD), which has a rapid onset and serious consequences.

OBJECTIVE

This study aimed to identify the risk factors of AECOPD complicated with T2RF and establish a predictive model to provide early warnings for the disease.

METHODS

A total of 1252 patients over 40 years old with AECOPD were selected in 7 affiliated medical institutions of the Chongqing Medical University from January 1, 2014, to December 31, 2020. These patients were divided into two groups: the case group (n = 242) and the control group (n = 1010), according to the occurrence of T2RF during hospitalisation. Univariate analysis and the ‘least absolute shrinkage and selection operator (LASSO) model with multivariate logistic regression’ were used to screen independent risk factors. Three machine learning algorithms, random forest (RF), XGBoost and support vector machine (SVM), were used to construct the prediction model, and the logistic model was used as the control model. A nomogram was established based on the logistic model and proved to have good calibration and clinical applicability.

RESULTS

A total of 24 indicators were included in the study, among which 17 were selected by univariate analysis with statistically significant differences. Five independent risk factors were screened out by the ‘LASSO model with multivariate logistic regression’, including the duration of disease, procalcitonin, D-dimer, the neutrophil/lymphocyte ratio and pulmonary ventilation function. The area under the ROC curve of the logistic, RF, XGBoost and SVM models were 0.886, 0.903, 0.876 and 0.869, respectively, in the test set.

CONCLUSIONS

The clinical prediction model constructed in this study has a good predictive effect on AECOPD complicated with T2RF, and it can be used to predict the same in Chongqing.
Geospatial Heterogeneity of Hidradenitis Suppurativa Searches in the United States: Infodemiology Study of Google Search Data (Preprint)
Authors: Kulkarni Vishnutheertha , Okoye Ginette A , Garza Luis A , Wongvibulsin Shannon
Published: November 2021

UNSTRUCTURED

N/A
'Effectiveness Of A Peer Support Intervention Program On Obesity Control Among Women In A Rural Area Of Turkey' (Preprint)
Authors: Bilgin Şahin Berna , Eser Erhan
Published: November 2021

BACKGROUND

Obesity in women is one of the leading public health problems globally. Peer support interventions have been effective in many areas of health promotion, and they have also been successful in obesity prevention and treatment.

OBJECTIVE

The purpose of this research was to reduce the Body Mass Index, fat ratio, and fat amount of the targeted women through the support of their peers (leading women) by regulating nutrition and improving physical activity in a rural community.

METHODS

This is a quasi-experimental obesity peer-led intervention study called the Leading Woman Model. At baseline, the obesity prevalence was found to be 60.5% among women aged 18–64 (n = 655) living in a rural district of Turkey. Of the participants (n = 137), 86.9% completed the 3rd month and 78.1% the 6th month of the intervention. Leading women (n = 11) were recruited from the community to supervise and monitor their own target groups of women during the intervention, which included supervised balanced nutrition and regular physical activity.

RESULTS

The mean age of the target intervention group was 42.8 ± 12.2. Significant improvements were observed in the body weight of the participating in the 3rd (-1.15 ± 2.51 kg) and 6th month (-1.13 ± 4.15 kg) of the intervention (p <0.05). Of the women, 10.9% lost at least 5% of their weight by the 3rd month and 13.1% by the 6th month of intervention, and 8.4% and 11.2% of the women achieved a better BMI category in the 3rd and 6th month of intervention, respectively.

CONCLUSIONS

Community-based obesity interventions are challenging but much more promising than those based at a facility. We suggest the Leading Women Model for community-based obesity interventions in women.
Cadena de valor sustentable de la apicultura en la Ciudad de México apoyada en la innovación sociocultural
Authors: Huerta Barrientos Aída , Saldaña Cabrera Miguel Ángel , Ávila Callejas Laura Patricia , Vera Morales Alma Elia
Published: November 2021

The general goal of this research is to determine the necessary criteria to design a sustainable value chain for beekeeping in Mexico City, with the support of sociocultural innovation and understood as the process of gradual change through action research in localized territories. First, the historical background of beekeeping in Mexico is presented to understand the importance of this activity in the development of cultures. Next, the materials and methods used for the development of this study are described. After that, the main results obtained in this study and their discussion are presented. Finally, the general conclusions are issued.
The relevance of socio-cultural innovation is that it can be favored through beekeepers associations in cooperatives, since these are highly preferred as organization schemes, which provide a solution to most of the rural business operation challenges.
Etnografía Antigua General del Estado de Oaxaca
Authors: Maldonado Alvarado Benjamín
Published: November 2021

La etnografía ofrece una mirada esencial sobre la vida de las sociedades y grupos humanos por su cercanía con ellos. En el caso de México y, en específico, de Oaxaca se ha centrado en los pueblos indígenas, pero eso no ha contribuido necesariamente a conocerlos a plenitud ni al reconocimiento de sus derechos, ni a su visibilización.

Los pueblos indígenas de México son una realidad visible y contundente, a raíz del surgimiento del Ejército Zapatista de Liberación Nacional (EZNL), en el estado de Chiapas, en enero de 1994, pero esa presencia era una realidad desconocida. Pese a décadas de estudios y políticas públicas dirigidos a los pueblos indígenas, ni la academia ni las instituciones de gobierno tenían claro quiénes conformaban esas comunidades. Numerosas investigaciones mostraban el conocimiento profundo de diversos aspectos de la cultura indígena y de la vida comunitaria, pero se trataba de estudios locales, a veces microrregionales, temáticos o relativos a alguna población, que no mostraban un panorama general de los pueblos indígenas de Oaxaca.
Technology-Based Decision Making in Inclusive Education
Authors:   University of Plovdiv “Paisii Hilendarski”,   University of Sofia “Snt. Kliment Ohridski”
Published: November 2021

Technology-based decisions in education are made on a daily basis. For some students, inclusive education is impossible without assistive and adaptive technologies. A study was conducted using the method “focus groups with one moderator”. The discussions explore the decision-making process for technology-based learning and the advantages and disadvantages of technology-based learning. The method provides an opportunity for individual and group intellectual and praxeological reflection on the discussed issues. The reflexive processes in the respondents allow to deduce the levels of their digital competence. The qualitative research was conducted with 65 inclusive teachers from secondary school and high school. The teachers participating in the study were selected according to a basic criterion: to make technology-based decisions for the implementation of inclusive processes in school. The main aspects for future analysis are mobility, accessibility, functionalities of technologies, application of the model of technology-based learning in inclusive education and factors that influence the decision-making process for choosing different spaces of technology-based learning. By making technology-based decisions the respondents create conditions for self-reflection about the application of technologies for the implementation of the processes of inclusive education. Reflexive analysis for technology-based decisions leads to increased intellectual, personal and praxeological reflection in the respondents. As a consequence of the increased manifestations of reflection in the respondents, conditions are created for personalized teaching and personalized learning in students, and personalized learning in turn paves the path of inclusive processes.
O BRINCAR LIVRE EM COMPOSIÇÕES CURRICULARES NO ENSINO FUNDAMENTAL: PERSPECTIVANDO UMA EDUCAÇÃO MENOR
Authors: Farias Freire Raic Daniele , Cardoso Marilete Calegari , Souza Josemary da Guarda de
Published: November 2021

Este artigo busca tensionar e discutir a ideia do brincar livre como um conteúdo escolar que vem sendo desprezado e invisibilizado pelas proposições curriculares dominantes, seja no ambiente escolar, seja no ambiente domiciliar. Investe no verbo "criançar" como uma condição da infância com todas as suas astúcias, curiosidades, liberdades e potências de criação. Trata-se de uma cartografia que busca traçar o plano comum, assumindo a transversalidade que lhe é necessária. Desse modo, vai ao encontro de dois outros estudos anteriormente produzidos - Baú Brincante e Catadores do Brincar – cujos acervos permitiram, em seus atravessamentos, capturar registros e narrativas de professores participantes que ajudaram a argumentar e a propor composições curriculares “menores”, caras a este estudo atual. Apoiando-se na filosofia da diferença, sobretudo na ideia do “currículo menor”, esse trabalho sinaliza para os necessários movimentos de perspectivar currículos abertos ao "criançar", como modo de afirmar o desejo da criança e os seus processos de singularização.
FILOSOFIA E EDUCAÇÃO E A RESISTÊNCIA AO PRESENTE
Authors: Santos Zamara Araujo dos
Published: November 2021

Este artigo tem como objetivo situar o pensamento de Deleuze e Guattari acerca da relação entre filosofia e educação delineando o plano de imanência filosófico e a experiência de ensinar e aprender na perspectiva de uma resistência ao presente. Sob tal configuração, visa-se traçar um diagnóstico do nosso tempo, das imagens de pensamento e suas determinações, da máquina de ensino e suas implicações; e investigar as condições imanentes de uma resistência e um combate que nos conecte com um projeto de reversão empirista e crença no devir.
AFORISMO SOBRE O ECODESIGN
Authors: Guattari Félix , Lima Vladimir Moreira
Published: November 2021

Tradução:

AFORISMO SOBRE O ECODESIGN

JÁ JOGAMOS TODAS AS CARTAS DO VIRTUAL? - Entrevista om Félix Guattari realizada no dia 29/01/91 por J.C Conesa e V. Lemarchands.

Este aforismo e a entrevista que o acompanha foram publicados em Caravelles 2. 2ème quadriennale internationale de design, Lyon: Caravelles, 22 de junho de 1991.
Characteristics of audit committees and banking sector performance in GCC
Authors: Elbahar Ehab R. , El-Bannany Magdi , El Baradie Mohamed
Published: November 2021

The purpose of this paper is to investigate the association between bank performance and audit committee characteristics for banks in Gulf Cooperation Council (GCC) over the period from 2013 to 2017. Regression of ordinary least squares quantile (OLS) and regression of quantile data are used to test the relationship between bank performance as a dependent variable and certain independent variables. The results revealed that committee size has a significant impact on banks’ performance but the presence of women members, independent members, committee meetings, and the existence of qualified members do not. The current study is one of a few studies, which addresses the association between bank performance and audit committee characteristics for banks in GCC.
Correlated evolution of distinct signals associated with increased social selection in female white-shouldered fairywrens
Authors: Jones John , Odom Karan , Hoppe Ian , Nason Doka , Ketaloya Serena , Karubian Jordan
Published: November 2021

Conspicuous female signals have recently received substantial scientific
attention, but it remains unclear if their evolution is the result of
selection acting on females independently of males or if mutual
selection facilitates female change. Species that express female, but
not male, phenotypic variation among populations represent a useful
opportunity to address this knowledge gap. White-shouldered fairywrens
(Malurus alboscapulatus) are tropical songbirds with a
well-resolved phylogeny where female, but not male, coloration varies
allopatrically across subspecies. We explored how four distinct
signaling modalities, each putatively associated with increased social
selection, are expressed in two populations that vary in competitive
pressure on females. Females in a derived subspecies (M. a.
moretoni) have evolved more ornamented plumage and have shorter tails
(a signal of social dominance) relative to an ancestral subspecies
(M. a. lorentzi) with drab females. In response to simulated
territorial intrusions broadcasting female song, both sexes of M.
a. moretoni are more aggressive and more coordinated with their mates
in both movement and vocalizations. Finally, M. a. moretoni songs
are more complex than M. a. lorentzi, but song complexity does
not vary between sexes in either population. These results suggest that
correlated phenotypic shifts in coloration and tail morphology in
females as well as song complexity and aggression in both sexes may have
occurred in response to changes in the intensity of social selection
pressures. This highlights increased competitive pressures in both sexes
can facilitate the evolution of complex multimodal signals.
Management of severe low back pain with a focused vibro-percussion wave treatment: A Case Report
Authors: Alsalamah Norah , Bartel Lee
Published: November 2021

A 49 year-old male with severe low back pain showed multilevel disc
bulges with spinal stenosis. After 18 treatments of low-frequency
vibro-percussion stimulation initial VAS pain score of 9.5 reduced to
2.5 and the Rolland-Morris score of 13 reduced to 3. The MRI showed some
resolution of L3-L4 and L4-L5.
Entrevista com Demi Getschko
Authors: Santaella Lucia
Published: November 2021

Antes de tudo, aqui vêm os agradecimentos da Revista TECCOGS por você ter gentilmente aceitado responder a esta entrevista, aliás, esta é a revista do PEPG de Tecnologias da Inteligência e Design Digital, que tem a honra de contar com sua presença no corpo docente. Demi Getschko é também diretor presidente do Núcleo de Informação e Coordenação do Ponto BR (NIC.br).
How can we change habits?
Authors: Colapietro Vincent , Nöth Winfried , Cestari Guilherme Henrique de Oliveira , Bittencourt Levy Henrique
Published: November 2021

W.N.: Good afternoon, we are here to speak about a very difficult topic: how to change habits. Peter Sloderdijk launched a book, translated into English as “You must change your life”. We were more respectful and put it in the form of a question: How do we change habits? But the presupposition of this question is the same, you cannot ask how you change a habit if you are not convinced that you must change habits, and life is habits, is it not? Well, of course, the background of our dialogue is Peirce’s conception of life and habits, but perhaps not only. We are here to meet and to speak in a series of online reflections. This is the third. A week from now we have a fourth. Without further ado, Professor Vincent Colapietro, whom you must know by now, is ready to speak about this topic, and we thank him very much for being with us once more.
Pengaruh Ekstrak Buah Lerak (Sapindus rarak) dan Beberapa Adjuvan terhadap Perkecambahan Gulma Fimbristylis miliacea
Authors: Pujisiswanto Hidayat , Nurmiaty Yayuk , Sriyani Nanik , Efrima Annisa
Published: November 2021

Adjuvant is an ingredient added in a formulation to increase the effectiveness of lerak fruit in inhibiting weeds. This study aims to determine the type of adjuvant in lerak fruit extract that can increase the inhibition of germination of Fimbristylis miliacea and to determine the type of adjuvant in lerak fruit extract that is most effective in inhibiting the germination of F. miliacea. The research was conducted from December 2019 to March 2020 in the Weed Laboratory, Faculty of Agriculture, University of Lampung. This study used a Completely Randomized Design (CRD) to determine the type of adjuvant given to lerak fruit extract on F. miliacea germination with 4 replications. The treatments consisted of lerak fruit extract, lerak fruit extract + VCO adjuvant, lerak fruit extract + KAO adjuvant, lerak fruit extract + Polysorbate 80 adjuvant, and control. The Bartlett test was used to test the homogeneity of variance, if the assumptions of the analysis of variance were met, then the mean value of the treatment was continued with the Least Significant Difference (LSD) test at the 5% level. The results showed that adjuvants and without adjuvants added to lerak fruit extract at a concentration of 50% (500 g/l) were able to suppress the percentage of germination and the speed of germination of Fimbristylis miliace seeds.Keywords: adjuvants, lerak fruit extract, Fimbristylis miliacea, weed
Application of Eigenvalues and Eigenvectors in Correlating Density and Fire Properties of Some Selected Woods in South-East Nigeria
Authors: Okafor Vincent Nwalieji , Enweonye Igwebuike , Umennadi Patrick Ugochukwu
Published: November 2021

Data sourced from literature for wood density (WD) and fire properties for fifteen Nigerian woods were analysed. The fire properties are ignition time (IT), flame propagation rate (FPR), flame duration (FD), afterglow time (AGT), ash formation (AF) and limiting oxygen index (LOI). The aim was to correlate density and fire properties of wood using eigenvalues and eigenvectors. The analysis tool adopted was the statisticalanalysis system (SAS) where principal component and regression analyses were performed. Based on the presented data and analyses, WD was found to relate well with FPR, AGT and LOI with an adjusted R-Square = 83% while the other three parameters: IT, FD and AF constitute random noise.

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Low-Cost Pulmonary Ventilator for Patient Monitoring for Covid-19 Disease
Authors: Rakib Md Abdullah Al , Rahman Md. Moklesur , Samad Mousume , Islam Sanjib , Rahman Md. Ashiqur , Abbas Fysol Ibna
Published: November 2021

Positive pressure ventilation has been an important component of respiratory disease management for the last 50 years. External instruments called ventilators are intended to help a patient accomplish a certain operation. It is to maintain or enhance a person's breathing capacity if he has a problem with his own breathing. It is a piece of equipment, software application, or product scheme that is used to increase, sustain, or boost the functional capacities of people with pulmonary difficulties. The developed system of a lab model ventilator is the subject of this article. The ventilator's robustness and functionalities, which are not only easily adaptable but also exact lower cost and cost-effective. The proposed design for a ventilation system was constructed with wooden parts weighing 6 kg and measuring 14×7×9 inches in dimension. It works without essential to the human hand since it breathes by the compression of a traditional bag-valve mask. In addition, it has a low-battery warning system as well as an assist control. Thismethod implemented is novel, low - cost, less dependent on external power and easy to manage.
Response of Different Explants for Callus Induction in Cucumber
Authors: Sultana Hasina , Nahar Lutfun , Hossain M. Mofazzal , Ghosh Totan Kumar , Biswas Md. Sanaullah
Published: November 2021

In vitro regeneration of cucumber is relatively difficult for genetic improvement. In this regard, different concentrations of growth regulators and three types of explants (cotyledon, hypocotyl and leaf disc) were investigated for their efficiency on callus induction potential. Among different explants explored for callus induction with different concentrations of 2,4-dichlorophenoxyacetic acid (2,4-D), leaf disc responded earlier (4.67 days) and showed higher percentage of callus induction (91.50%) with 2 mg/l 2,4-D supplemented Murashige and Skoog (MS) media. The same concentration of 2,4-D resulted in the maximum callus fresh (0.56 g) and dry weight (0.39 g) from leaf disc explant. Then the callus was transferred to untreated, 2.0 mg/l BAP + 0.2 mg/l NAA + 1.0 mg/l Kn, 2.0 mg/l BAP + 1.0 mg/l NAA + 1.0 mg/l Kn and 2.0 mg/l BAP + 1.5 mg/l NAA + 1.0 mg/l Kn fortified MS medium. After transferring the callus of different explants to shoot regeneration media containing different concentrations of 6-benzylaminopurine (BAP), 1-naphthaleneacetic acid (NAA) and Kinetin (Kn), only cotyledon callus started to regenerate shoot. The combination of BAP (2 mg/l) + NAA (0.2 mg/l) + Kn (1 mg/l) showed highest shoot regeneration percentage (67.77%) and the maximum number of shoots (5.12) per explant were recorded in the treatment combination of 2 mg/l BAP + 0.2 mg/l NAA + 1 mg/l Kn. These results provided a basis for the optimization of the callus induction protocol of cucumber for genetic transformation.
Identifying the Main Factors of Iran’s Economic Growth Using Growth Accounting Framework
Authors: Mahmoudi Mohammadreza
Published: November 2021

This paper aims to present empirical analysis of Iranian economic growth from 1950 to 2018 using data from the World Bank, Madison Data Bank, Statistical Center of Iran, and Central Bank of Iran. The results show that Gross Domestic Product (GDP) per capital increased by 2 percent annually during this time, however this indicator has had a huge fluctuation over time. In addition, the economic growth of Iran and oil revenue have close relationship with each other. In fact, whenever oil crises happen, great fluctuation in growth rate and other indicators happened subsequently. Even though the shares of other sectors like industry and services in GDP have increased over time, the oil sector still plays a key role in the economic growth of Iran. Moreover, growth accounting analysis shows contribution of capital plays a significant role in economic growth of Iran. Furthermore, based on growth accounting framework the steady state of effective capital is 4.27 for Iran’s economy.
The Moderating Effect of Environmental Innovation on the Relationship between Corporate Social Responsibility and Environmental Performance: Proposal of a Theoretical Model
Authors: Burak Mehmet Fatih
Published: November 2021

Today, it becomes indispensable for businesses to have socially responsible behaviors and environmental approaches. Businesses should prioritize corporate social responsibility (CSR), environmental innovation and environmental performance in order to avoid global environmental problems that may emerge as a result of irresponsible behaviours and lack of environmental protection. This study aims to propose a theoretical model for the relationship between CSR, environmental innovation and environmental performance. For this purpose, the relations between the variables were examined in the light of research and studies in the literature and a theoretical model was proposed based on the information obtained.
Mediating Role of Absorptive Capacity on the Relationship between Foreign Direct Investment and Local Firm’s Performance
Authors: Wanjere M. D. , Iraki X. N. , Ogutu M. O. , Kinoti M.
Published: November 2021

There is little documentation on the role of absorptive capacity on the relationship between FDI and performance of firms. This paper investigates the mediating role of absorptive capacity on the relationship between FDI and performance of manufacturing firms in Kenya. The population of study comprised 100 companies registered with Kenya Association of Manufacturers that had over 10 percent foreign ownership as at the time of data collection in 2019. The respondents were the CEOs of organization or their designated officers. The study used a structured questionnaire to collect primary data. The respondent were required to indicate how the introduction of FDI impacted on organizations capital flow, advanced production technology, marketing expertise and management knowhow. They were also to indicate the extent their Organisation had invested in absorptive capacity and the effect absorptive capacity had on the relationship between FDI and local firm performance. Descriptive and inferential statistics were both used to analyze the data. The results revealed that absorptive capacity has statistically significant mediating effect on the relationship between FDI and firm performance. This imply that an incremental change in the absorptive capacity would generate growth in company’s performance. As such Kenyan and other sub-Sahara African countries government need to come up with polices geared to supporting improvement of firms absorptive capacities so as to spur the growth of their key sectors of the economy.
Blockchain and High-Performance/Low-Cost Ambient Sensors Mounted on Open Field Servers-Based IoT-Oriented Information-Sharing System for Agricultural Fields
Authors: Kawakura Shinji , Hirafuji Masayuki , Shibasaki Ryosuke
Published: November 2021

Our research group focuses on creating various application systems of these systems tends to focus on agricultural (agri-) advancement and security issues. First, we monitor agriculture and related environments (e.g., rice fields, meadows, and gardens) and obtain environmental agri-information (e.g., temperature, moisture, and the quality of soil) over extended periods. To do so, we use an existing Japanese high-performance/low-cost field server (FS) system, which operates sensor units uniformly. Furthermore, we develop and implement a blockchain and Twitter-based record sharing system connecting with the FS for the benefit of traditional agri-researchers, workers, and their respective managers. In regard to the study results, presenting the accuracy data quantitatively is difficult; we are unable to show the success and error rates for the systems’ data transmitting and receiving, nor the examination operation time. We believe the holistic system holds the potential to improve not only agri-businesses but also agri-skills and overall security levels.
Modulation of Yield and Yield Attributes of Transplanted Aman Rice through Organic and Inorganic Fertilization in Terrace Soil
Authors: Alam Md. Ashraful , Rahman Md. Mizanur , Rahman Khan Md. Arifur , Shiragi Md. Humayun Kabir , Islam Majharul , Morshed Monjur
Published: November 2021

Rice production has increased almost doubled over the last decade in Bangladesh as a result of additional application of chemical fertilizers and high yielding varieties. Present experiment was undertaken for elucidating the combined effect of organic materials (OM) and nitrogen (N) fertilizer on yield contributing attributes and yield of transplanted aman ( T. aman) rice. Experiment was set in a factorial randomized complete block design (RCBD) with three replications. Five types of OMs viz. RS (rice straw), VC (vermicompost), RHB (rice husk biochar), CD (cowdung) and PM (poultry manure) considering two ton carbon per hectare and three level of N viz. N0, N100 and N150 kg ha-1 were used in this experiment. Findings revealed that among the five OMs; cowdung significantly improved the studied parameters. Besides 150 kg ha-1 dose of N has pronounced effect on the grain yield of T. aman rice. In general OMs alone cannot contribute to the maximum yield and yield contributing parameters. Maximum plant height (98.5cm), no of tillers (20), no of effective tillers (18), no of grains (145.0 g), no of filled grains (138), no of unfilled grains (7.0) per panicle, length of panicle (27.5 cm), 1000-seed weight (23.65g), straw yield (8.97 t ha-1), grain yield (5.41 t ha-1) and biological yield (14.34 t ha-1) was attributed by the mixed application of PM and N150 dose of nitrogen. While maximum harvest index (45.09%) was found in the plot received RS in combination of N150 treatment and its minimum value was recorded also solely in RS treated plot. Findings suggest that the use of PM along with 150 kg ha-1 N can render superior crop growth and yield of T. aman rice.
Brief Introduce of Planetary K-index: An Indicator of Geomagnetic Storms
Authors: Lin Jyh-Woei
Published: November 2021

The planetary K-index (Kp index) was a geomagnetic index in the H-component field. This index was calculated from data collected by a network of 13 ground-based magnetometer stations at mid-latitude locations from the International Real-time Magnetic Observatory Network (INTERMAGNET). The magnitudes of Kp index could indicate geomagnetic activity using the integer K-scale from 0 to 9 without dimension because the K-scale was estimated using the quasi-logarithms algorithm. The Kp index indicated geomagnetic storms under the condition of K-scale＞4. The three-hourly Kp index has been commonly used. The three-hourly Kp index was relatively stable for low‐variability geomagnetic activity. The hourly Kp index represented the level of auroral absorption with a more accurate characterization. For future research, the Kp index with a high sampling rate (e.g., ＜1 hour) could be considered, so that a very accurate characterization was characterized the more detailed geomagnetic activity of global region.
A Classical Approach to Nuclear Instability
Authors: Selke David L.
Published: November 2021

We extend a classical model of nuclei to include geometry as well as electron-like shells, then apply the model to the moments leading up to nuclear decay. The model leads to the well-known half-life or constant probability of a given nucleus to decay in a given time.