bluuebunny/crossref_metadata_2025 huggingface dataset:
Quantifying the effect of fiber pennation angle on shear wave viscoelastography estimates: In silico and phantom studies
Authors: Chandra Akash , Bezabh Mekdes Wubet , Mercado-Shekhar Karla P.
Published: February 2025

Ultrasound shear wave elastography can be useful for assessing muscle pathology. The effect of anisotropy on shear wave elasticity estimates of skeletal muscle has been reported previously. However, muscle is inherently viscoelastic, and hence, tissue viscosity is also an important material parameter to assess. The goal of this study was to systematically quantify the effect of fiber pennation angle on shear wave viscoelasticity imaging estimates. Numerical phantom simulations of skeletal muscle-mimicking phantoms were analyzed. Anisotropic polyvinyl alcohol phantoms embedded with polysulfone fibers were developed to mimic the viscoelasticity and appearance of muscle in B-mode images. Shear wave dispersion analysis, assuming a Kelvin–Voigt model, was performed to estimate the shear modulus and viscosity of the phantoms along the fibers (in-plane) and across the fibers (cross-plane) with varying pennation angles (0°–30°). A decreasing trend was observed in shear modulus estimates with increasing fiber pennation angle in the in-plane orientation for all phantoms. Notably, simulations showed that viscosity estimates decreased with increasing angle. These results provide a systematic quantification of the effect of fiber pennation angle on viscoelastic estimates under controlled conditions, which will be useful for assessing the performance of shear wave viscoelasticity imaging approaches for muscle assessment.
Balancing the Load: Perceived Stress, Burnout, and Coping in Irish Athletic Therapy Students
Authors: O’Connor Siobhán , Tarmure Maftei Ionut , O’Keeffe Sinéad
Published: February 2025

Prolonged stress, poor coping skills, and a lack of engagement in self-care activities can contribute to burnout. We investigated perceived stress, burnout, and coping in Irish athletic therapy students. Moderate stress (20.5 ± 6.7), personal (57.5 ± 20.4), and work-related burnout (52.7 ± 18.1), along with low resilient coping (13.7 ± 2.4), overall (46.0 ± 15.6) and client-related (26.7 ± 17.2) burnout were noted. Women athletic therapy students presented with higher overall (r = .17, p = .04), personal (r = .20, p = .02), and work-related (r = .17, p = .03) burnout and lower resilient coping (r = .20, p = .02). Students working longer hours in employment had higher work- (r = .19, p = .04) and client-related (r = .19, p = .04) burnout scores. Thus, interventions to alleviate stress and burnout and enhance coping skills in students embarking on their career are urgently needed. Targeted strategies for women and those working a high number of hours in external employment are particularly required.
Effective conservative management of delayed pancreatic injury
Authors: Obeid Amir , Hershko Dan , Darawshy Abd El Karim , Abu Wasel Bassam
Published: February 2025

Pancreatic injuries due to blunt abdominal trauma are rare and present significant diagnostic and management challenges. This case report discusses the conservative management of a young patient with a traumatic pancreatic body transection following a motor vehicle accident, emphasizing the importance of a multidisciplinary approach and demonstrating the potential for successful non-operative management in select cases.
Psychosocial and mental health in cystic fibrosis in the modern era of care: time to evolve
Authors: Harrigan Maggie , Georgiopoulos Anna M , Quittner Alexandra L , Smith Beth , Douglas Tonia A
Published: February 2025

Cystic fibrosis (CF) treatment has revolutionised care over the past three decades with major advances in survival. Despite these advances, CF continues to create psychological and social challenges for people with CF (PWCF) throughout their life and is associated with worse health outcomes and higher healthcare costs. Anxiety and depression screening and management protocols are widely implemented within CF care; however, a much broader scope of psychosocial challenges exist which lack a standardised screening and management approach. The advent of CF transmembrane conductance regulator modulator therapies is transforming the psychosocial landscape for PWCF with new challenges and evolving psychosocial needs. What it means to have CF, the expectations, hopes and stressors are rapidly changing, and psychosocial care must keep pace if health outcomes are to be fully optimised. A symposium of international CF and psychosocial experts was convened in November 2022 to explore current and emerging issues in psychosocial health and identify opportunities and approaches to optimise psychosocial care. This state-of-the-art review summarises key symposium proceedings and highlights priorities for clinical practice and research in psychosocial health across the lifespan among PWCF. It also summarises state-of-the-art initiatives for screening and intervention to optimise CF psychosocial healthcare and patient outcomes.
How to build a framework to establish a patient research partner network in rheumatology research: a report of a 2-year implementation project
Authors: Buerki Kristina , Toitou Melpomeni , de Wit Maarten , Grealis Stacey , Ludwig Silke , Britt Chantal , Klett Florian , Steeb Isabelle , Maletic Tanja , Eisenring Andreas , Timpert-Argust Penelope Jane , Diem Dania , Micheroli Raphael , Dudli Stefan , Bruni Cosimo , Camarillo-Retamosa Eva , Dobrota Rucsandra , Hoffmann-Vold Anna-Maria , Ciurea Adrian , Ospelt Caroline , Distler Oliver , Elhai Muriel
Published: February 2025

Background

Patient research partners (PRPs) are people living with a relevant disease who actively contribute to research. Their contribution is beneficial for any research project. Although the inclusion of PRPs in rheumatology research is increasingly recommended, its practical implementation, particularly in translational research, remains limited . Enhancing PRP engagement requires a clear understanding of the necessary steps.

Objective

This study aims to show steps to achieve successful collaboration between PRPs and researchers in clinical and transitional research in rheumatology.

Methods

We established a PRP network by following five main steps: setting up infrastructure, recruitment, training, PRP involvement at an early stage, and ongoing support. We adhered to overall principles of openness, feedback, and regular evaluations to create a respectful and collaborative environment. The initiative was qualitatively assessed via an online questionnaire developed by each six researchers and PRPs.

Results

Communicating our initiative at laboratory open days and to patient associations has enabled to create a network of 66 PRPs. A match-making tool was introduced to allocate interested PRPs with a project request. This led to PRP involvement in 15 projects, including 9 in translational research. Two PRP-coordinators provided support including glossaries and educational courses .

Conclusion

Our initiative outlines five essential steps for establishing PRP collaboration in rheumatology research, including translational research. This approach benefited both PRPs and researchers and might serve as a guide for other centres.
Solar Induced Photocatalytic degradation of textile dyes using composite of indium oxide and silver vanadate
Authors: Shahid Tazeen , yasmin nazia , Kosar Shazia , Khalid Arooma , Naz Robina , Maria Hafiza , Safdar Muhammad , Mirza Misbah
Published: February 2025

In the present endeavor, the synthesized samples Indium oxide (In2O3), Silver vanadate (Ag3VO4) and composite (In2O3/Ag3VO4) is prepared by using co-precipitation method. These samples showed a very effective photocatalytic response for the degradation of a dye methylene blue (MB) in the presence of sunlight. The physical properties of samples are characterized by XRD, SEM, FTIR and UV Spectroscopy. The structure analysis and crystalline size of prepared samples were examined by XRD. Debye Scherrer’s formula had been used to calculate the crystalline size and its value is 19.1nm of In2O3, 10.8nm of Ag3VO4 and1.65nm of In2O3/Ag3VO4.FTIR absorption spectroscopy was carried out in the range of 500-4000cm-1 to verify the synthesized material’s structural properties. FTIR spectrum also provides the information about the material’s functional groups. The morphology of indium oxide, silver vanadate, and composite was analyzed by SEM. The calculated grain sizes of indium oxide, silver vanadate and In2O3/Ag3VO4 composite are 0.13μm, 0.72μm and 0.56μm respectively. The optical properties indicate a small band gap for composite, which is 1.65eV and showed strong absorption for sunlight. The photocatalytic degradation of MB was made by using prepared catalysts in the exposure of sunlight at wavelength 300-900nm by UV spectroscopy. Indium oxide degraded MB to 76.5%, silver vanadate degraded MB to 71% while the composite degraded to 85.5% of MB. The results of UV spectroscopy showed the composite is very effective in photocatalytic degradation MB dye.
Propagators in AdS for higher-derivative and nonlocal gravity: Heat kernel approach
Authors: Kolář Ivan , Málek Tomáš
Published: February 2025

We present a new covariant method of construction of the (position space) propagators in the N-dimensional (Euclidean) anti-de Sitter background for any gravitational theory with the Lagrangian that is an analytic expression in the metric, curvature, and covariant derivative. We show that the propagators (in Landau gauge) for all such theories can be expressed using the heat kernels for scalars and symmetric transverse-traceless rank-2 tensors on the hyperbolic N-space. The latter heat kernels are constructed explicitly and shown to be directly related to the former if an improved bi-scalar representation is used. Our heat kernel approach is first tested on general relativity, where we find equivalent forms of the propagators. Then it is used to obtain explicit expressions for propagators for various higher-derivative as well as infinite-derivative/nonlocal theories of gravity. As a by-product, we also provide a new derivation of the equivalent action (correcting a mistake in the original derivation) and an extension of the quadratic action to arbitrary

$${N\ge 3}$$

N
≥
3

dimensions.
Tight upper bound of the maximal quantum violation of Gisin’s elegant Bell inequality and its application in randomness certification
Authors: Hu Dan-Dan , Li Meng-Yan , Guo Fen-Zhuo , Wang Yu-Kun , Dong Hai-Feng , Gao Fei
Published: February 2025

The violation of a Bell inequality implies the existence of nonlocality, making device-independent randomness certification possible. This paper derives a tight upper bound for the maximal quantum violation of Gisin’s elegant Bell inequality (EBI) for arbitrary two-qubit states, along with the constraints required to achieve this bound. This method provides the necessary and sufficient conditions for violating the EBI for several quantum states, including pure two-qubit states and the Werner states. The lower bound of certifiable global randomness is analyzed based on the tight upper bound of the EBI for pure two-qubit states, with a comparison to the Clauser-Horne-Shimony-Holt (CHSH) inequality. The relationship between the noise level and the lower bound of certifiable global randomness with respect to the Werner states is also explored, and the comparisons with both the CHSH inequality and the chained inequality are given. The results indicate that when the state approaches a maximally entangled state within specific quantified ranges, the EBI demonstrates advantages over both the CHSH inequality and the chained inequality, providing theoretical guidance for experimental device-independent quantum random number generation.
Exploiting Dynamic Regular Patterns in Irregular Programs for Efficient Vectorization
Authors: Lei Kelun , Du Shaokang , You Xin , Yang Hailong , Luan Zhongzhi , Liu Yi , Qian Depei
Published: February 2025

Modern optimizing compilers are able to exploit memory access or computation patterns to generate vectorized codes. However, such patterns in irregular programs are unknown until runtime due to the input dependence. Thus, either compiler’s static optimization or profile-guided optimization cannot represent the patterns for any common input, which leads to suboptimal vectorization. To address the above drawback, we propose
DynVec
, a framework to automatically exploit regular patterns buried deeply inside irregular programs and apply corresponding optimizations for better vectorization. Due to the integration of workload distribution and the ability to represent instruction features and identify regular patterns with effective feature extraction and data re-arranging methods,
DynVec
can generate highly efficient vectorized codes for both serial and parallel irregular programs by replacing
gather
/
scatter
/
reduction
operations with optimized operation groups. We evaluate
DynVec
on optimizing irregular programs such as SpMV and graph programs with representative sparse matrix datasets. The experiment results show that
DynVec
achieves significant speedup compared to the state-of-the-art implementations across a range of X86 and ARM platforms.
Green Synthesis of ZIF-8 Combined with Ruthenium Nanoparticles for Enhanced Electrochemical Detection of Dopamine
Authors: Moumen Youssra , Wannassi Jassem , Bourigua Sondes , Castilla-Martinez Carlos A. , Barhoumi Houcine , Demirci Umit B. , Kahri Hamza
Published: February 2025

A green synthesis approach was employed to develop ZIF-8, a Metal-Organic Framework (MOF) with high porosity and stability. To enhance its functionality for sensor applications, ZIF-8 was doped with ruthenium (Ru) nanoparticles, yielding Ru@ZIF-8. The structural and morphological characteristics of both ZIF-8 and Ru@ZIF-8 were systematically evaluated using X-ray diffraction (XRD), scanning electron microscopy (SEM), Brunauer–Emmett–Teller (BET) surface area analysis, and infrared (IR) spectroscopy. Electrochemical studies revealed the excellent sensitivity and selectivity of Ru@ZIF-8 compared to pristine ZIF-8. Specifically, the sensitivity of the ZIF-8-based sensor was evaluated at 0.0035 μA·μM−1, with a limit of detection (LOD) of 2 μM, whereas Ru@ZIF-8 exhibited significantly enhanced sensitivity of 0.141 μA·μM−1 and a detection limit of 0.05 μM. Both materials were further validated in real sample analyses using serum, demonstrating their applicability in complex biological matrices. The novelty of our work introduces a novel Ru@ZIF-8 sensor for dopamine detection, combining Ru nanoparticles and the ZIF-8 matrix to achieve superior performance. The sensor demonstrates exceptional sensitivity, a lower detection limit, a broader linear range and high selectivity against common biological interferences, surpassing conventional systems. This work underscores an environmentally friendly strategy for synthesizing advanced composites based on MOFs with enhanced detection capabilities for real-world applications.
TRPA1 channels modulate cutaneous vasodilation during exercise in the heat in young adults when NOS is inhibited
Authors: Hattori Rei , Kajiki Masanobu , Fujimoto Tomomi , Amano Tatsuro , Kenny Glen P. , Watanabe Koichi , Nishiyasu Takeshi , Fujii Naoto
Published: February 2025

We demonstrated that the administration of TRPA1 channel antagonist HC030031 only appears to attenuate cutaneous vasodilation during exercise in the heat when nitric oxide synthase (NOS) is inhibited. TRPA1 channels may function as a “backup system” to maintain cutaneous vasodilation when NOS-dependent vasodilation is compromised during exercise in the heat.
Comprehensive immune landscape in allergic conjunctivitis: insights from Mendelian randomization analysis
Authors: Cai Yuchen , Zhou Tianyi , Shi Wenjun , Cai Xueyao , Ding Xia , Fu Yao
Published: February 2025

Introduction: Current understanding of the immune landscape underlying allergic conjunctivitis (AC) remains rather limited. We investigated the potential association between circulating immunophenotypes and AC using Mendelian randomization (MR) methodology.
Methods: Based on genome-wide association studies (GWAS) summary-level statistics, a 2-sample MR was employed to analyze the bidirectional causal relationships between 731 circulating immunophenotypes and AC risk.
Results: A total of 33 genetically predicted immunophenotypes were significantly associated with AC risk. A protective effect of 18 immunophenotypes against AC was found, such as CD3 on CD39+CD8br (Inverse variance weighted [IVW] odds ratio [OR] = 0.936, 95% confidence interval [CI]: 0.925-0.985, p = 0.003) and CD25 on CD28+CD4+ (IVW OR = 0.921, 95% CI: 0.863-0.983, p = 0.013). Conversely, 15 immunophenotypes were found to be significantly associated with AC risk, such as CD25 on IgD–CD38dim (IVW OR = 1.042, 95% CI: 1.012-1.073, p = 0.006). Reverse MR based on these 33 genetically predicted immunophenotypes suggested that AC also had a significant influence on four circulating immune cells, including CD33–HLA DR– AC (IVW OR = 1.187, 95% CI: 1.034-1.362, p = 0.015), CD3 on CD39+CD8br (IVW OR = 0.876, 95% CI: 0.779-0.985, p = 0.027), HLA DR on CD14+ monocyte (IVW OR = 0.831, 95% CI: 0.725-0.953, p = 0.008), and CD39 on CD39+ secreting Treg (IVW OR = 1.123, 95% CI: 1.002-1.259, p = 0.046).
Conclusion: Our study highlights the intricate association between immune cells and AC, providing a valuable basis for future mechanistic and therapeutic studies from an immunological perspective.
Exploring the Multifaceted Role of WT1 in Kidney Development and Disease
Authors: Lu Jing , Zhang Xiaohu , Liu Hanmin , Liu Yang
Published: February 2025

Background: The Wilms' tumor suppressor gene (WT1) is a critical regulator in kidney development and disease pathogenesis. With the identification of at least 36 isoforms in mammals, each potentially playing distinct roles, WT1's complexity is becoming increasingly apparent. The -KTS and +KTS isoforms, in particular, have been implicated in DNA and RNA regulation, respectively. This review consolidates recent insights into WT1's multifaceted role in renal morphogenesis and its implications in kidney diseases.
Summary: Our review highlights WT1's expression during embryonic kidney development and its maintenance in postnatal kidney function. We discuss the association of WT1 mutations with genetic nephropathies like Denys-Drash and Frasier syndromes, emphasizing its genetic significance. Additionally, we explore the implications of WT1 expression alterations in glomerular diseases, such as IgA nephropathy and lupus nephritis, where its role extends beyond a mere biomarker to a potential therapeutic target.
Key Messages: The WT1 gene and its protein products are central to understanding kidney morphogenesis and the molecular basis of renal disorders. As our understanding of WT1's regulatory mechanisms expands, so does the potential for developing targeted therapies for kidney diseases. This review calls for further research to elucidate the precise functions of WT1 isoforms and to explore the upstream regulators of WT1 that could offer novel treatment strategies for kidney pathologies. The significance of WT1 in intricate signaling pathways governing kidney health and disease is underscored, highlighting the need for continued investigation into this pivotal gene.
GROWTH DIFFERENTIATION FACTOR 15 KNOCKOUT MICE ARE PROTECTED FROM NEONATAL HYPOXIC-ISCHEMIC INJURY IN A SEX DEPENDENT MANNER
Authors: Herrmann Jeremy R. , Kochanek Patrick M. , Vagni Vincent A. , Janesko-Feldman Keri A. , Stezoski Jason P. , Jackson Travis C.
Published: February 2025

Introduction: Neuroinflammation plays a critical role in tissue injury and repair after neonatal hypoxic-ischemic (HI) brain injury and varies by sex. Growth differentiation factor-15 (GDF-15) is a cytokine released by macrophages during inflammation and is upregulated after brain ischemia. We examined the impact of GDF-15 knockout (KO) on volume loss and the combined microglia/macrophage response in the Rice Vannucci model of neonatal HI injury.
Methods: Male and female wild-type (WT) Gdf15+/+, heterozygous Gdf15nuGFP-CE/+ (Het), and homozygous Gdf15nuGFP-CE/nuGFP-CE (KO) mice were bred at the University of Pittsburgh. Postnatal day 9-11 mice were randomized to sham procedure or unilateral common carotid artery ligation followed by exposure to 8% O2 for 25min. Pups were subsequently genotyped and survived for 14 days before sacrifice. Lesion volume and number of ionized calcium-binding adapter molecule 1 (Iba-1) positive cells were quantified.
Results: Injured male KO pups had decreased hemispheric and hippocampal lesion volume vs. injured male WT pups. Injured male Het pups demonstrated an intermediate phenotype. In males, the number of Iba-1 positive cells correlated with extent of tissue loss. In females, the extent of volume loss and Iba-1 cell counts post-injury did not vary by genotype.
Conclusion: GDF-15 exerts a sex-dependent deleterious effect on lesion volume in a neonatal HI model. Future work should identify how GDF-15 mediates different neuroinflammatory responses between sexes, establish if brain-secreted vs. peripherally-derived GDF-15 mediates the pro-injury phenotype that was inhibited in male KOs, and test if therapeutic inhibition of GDF-15 signaling is a novel treatment for neonatal HI brain injury.
Utility of p16INK4a staining on cell blocks prepared from residual liquid-based cervicovaginal material
Authors: Ansari Shabana Andleeb , - Anshu
Published: February 2025

Introduction: Cervical cancer screening using Pap smears is affected by false-negative results. Liquid-based cytology (LBC) offers the technical advantage of preparing cell blocks from residual fluid to conduct ancillary tests on them. The p16INK4a gene product has been shown to be strongly overexpressed in dysplastic cervical epithelia and serves as surrogate marker for high-risk human papilloma virus (HPV) infection. Material and methods: Microwave-processed cell blocks were prepared from residual material in vials after ThinPrep slide preparation, stained with hematoxylin and eosin (H&E) and p16INK4a. Nuclear staining with or without cytoplasmic staining on p16 slides was considered positive. Four parameters were evaluated: percentage of positive cells, intensity of staining, number of positively stained cells in close contact and full-thickness epithelial staining. We compared sensitivity and specificity of ThinPrep smears and p16 stained cell blocks in diagnosing invasive malignancy. Results: The intensity and percentage of p16 positive cells was found to increase with increasing grade of cervical abnormality. We found good concordance between ThinPrep smear and cell block diagnoses in cases which were negative for intraepithelial lesion or malignancy (NILM) (97.6%), in low-grade squamous intraepithelial lesions (LSIL) (90%), high-grade squamous intraepithelial lesions (HSIL) (100%) and squamous cell carcinomas (SCC) (93.5%). Of 16 discrepant cases, nine were reported unsatisfactory on ThinPrep smears due to abundant necrosis or scant cellularity. All these turned out to have malignancies on follow up and review of histology. The sensitivity of ThinPrep and p16 stained cell blocks in diagnosing invasive malignancy were 70.2% and 85.1% respectively, while the specificity of both were 100%. Conclusions: Cell blocks prepared from residual fluid in LBC vials have the potential to reduce the rates of inadequacy and are feasible in routine practice. While the cost of p16 on cell blocks may be too prohibitive for use in routine cervical screening programmes, if used judiciously in combination with clinical suspicion, a lot of valuable material which is usually discarded in the residual LBC vials can prove to be crucial in arriving at the correct diagnosis.
Oxana L. Kolomiets: 42 Years at the Forefront of Meiotic Chromosome Study
Authors: Matveevsky Sergey N. , Grishaeva Tatiana M. , Spangenberg Victor E. , Mazheika Igor S. , Bogdanov Yuri F.
Published: February 2025

Obituary for the special issue "Chromosomal and Cellular Insights into Sexual Reproduction and Evolution", dedicated to Professor Oxana Kolomiets
Ocupação como texto: notas sobre as gramáticas de ação política de estudantes cearenses em 2016
Authors: Macêdo Daniel , Nunes Marcia Vidal
Published: February 2025

Após as jornadas de junho de 2013 e as ampliações de incursões em plataformas digitais para processos de mobilização social no Brasil, vivemos, em 2016, uma onda de manifestações mobilizadas em torno da #ocupatudo que expressava o descontentamento frente ao contexto de pós-impeachment. Para além do reconhecimento de que a adesão a tais plataformas reconfigura as dinâmicas dos movimentos sociais, tem nos interessado investigar as transformações em torno da forma de atuação política e, frente a este último caso, considerando as particularidades destas iniciativas de desobediência civil. Para isso, nos interessa tomá-las como um texto resultante de uma escrita política para, assim, mirarmos e discutirmos as relações entre dinâmicas online e offline que estruturaram as ocupações.
Pushing the boundaries of MEG based on optically pumped magnetometers towards early human life
Authors: Corvilain Pierre , Wens Vincent , Bourguignon Mathieu , Capparini Chiara , Fourdin Lauréline , Ferez Maxime , Feys Odile , De Tiège Xavier , Bertels Julie
Published: February 2025

Characterizing the early development of the human brain is critical from both fundamental and clinical perspectives. However, existing neuroimaging techniques are either not well suited to infants or have limited spatial or temporal resolution. The advent of optically pumped magnetometers (OPMs) has revolutionized magnetoencephalography (MEG) by enabling wearable and thus more naturalistic recordings while maintaining excellent sensitivity and spatiotemporal resolution. Nevertheless, its adaptation to studying neural activity in infancy poses several challenges. In this work, we present an original close-to-scalp OPM-MEG setup that successfully recorded brain responses to sounds in newborns. We exposed one-month-old infants to continuous streams of tones and observed significant evoked responses, which peaked ~250 ms poststimulus at bilateral auditory cortices. When tones were presented at a steady fixed pace with an oddball tone every fourth tone, significant neural responses were found both at the frequency of the standard tones (3 Hz) and of the oddball tones (0.75 Hz). The latter reflects the ability of the newborn brain to detect auditory change and synchronize to regular auditory patterns. Additional analyses support the added value of triaxial OPMs to increase the number of channels on small heads. Finally, OPM-MEG responses were validated with those obtained from the same participants using an adult-sized cryogenic MEG. This study demonstrates the applicability of OPM-MEG to study early postnatal periods; a crucial step towards future OPM investigations of typical and pathological early brain development.
Filling in the gaps for assassin bugs: taxonomic notes and new records of Reduviidae (Hemiptera: Heteroptera) from Neotropical countries
Authors: FORERO DIMITRI , MEJÍA-SOTO ANDRÉS
Published: February 2025

Six generic and 17 species level new country records are provided for Reduviidae (Hemiptera: Heteroptera) from various Neotropical countries. New country records: Brontostoma abbas Carpintero, 1980: Colombia; B. colossus (Distant, 1902): Colombia, Ecuador; Pothea jaguaris (Carpintero, 1980): Colombia; P. ventralis (Lepeletier & Serville, 1825): Colombia; Pseudopothea paulai Gil-Santana, 2015: Bolivia, Colombia; Rhiginia immarginata Stål, 1866: Colombia; Cidoria flava Amyot & Serville, 1843: Colombia; Corcia nigricornis Champion, 1899: Colombia; Pirnonota convexicollis Stål, 1859: Honduras, Costa Rica, Bolivia, and Peru; Pselliopus punctipes Amyot and Serville, 1843: Colombia; Repipta lepidula Stål, 1866: Colombia; R. sanguinea Champion, 1899: Colombia; Sosius foliaceus Champion, 1899: Colombia; Zelus championi Zhang & Hart, 2016: Colombia; Z. nigromaculatus Champion, 1899: Colombia; Aradomorpha championi Lent & Wygodzinsky, 1944: Colombia; Peregrinator biannulipes (Montrouzier & Signoret, 1861): Colombia. Detailed locality data from Colombia are provided for Rhiginia bimaculata Breddin, 1914 and R. conspersa Breddin, 1901, previously known only from country level records without more specific localities. To help identify Brontostoma abbas Carpintero, 1980, Repipta lepidula Stål, 1866 and R. sanguinea Champion, 1899, images of the male and/or female genitalia are provided for the first time. Habitus images are provided for all treated species, and additional structural details are illustrated for some of them.
A new sandstone-dwelling leaf-toed gecko (Gekkonidae: Dixonius hinchangsi) from Khon Kaen Province, northeastern Thailand
Authors: PAUWELS OLIVIER S. G. , DAS SUNANDAN , KUNYA KIRATI , SUMONTHA MONTRI , DONBUNDIT NATTASUDA , PAUWELS THOMAS P. C. , SONET GONTRAN , BRECKO JONATHAN , MEESOOK WORAWITOO
Published: February 2025

We describe Dixonius hinchangsi sp. nov. from a sandstone area near Hin Chang Si, Khon Kaen Province, northeastern Thailand. The new species differs from all currently recognized Dixonius by the following combination of morphological characters and pattern: maximal known snout-vent length of 50.1 mm, 12 longitudinal rows of dorsal tubercles; 30 to 34 paravertebral tubercles; 23 to 27 longitudinal rows of ventral scales across the abdomen; six to eight precloacal pores in males, no pores in females; no canthal stripe; strongly barred lips; and a spotted to uniform dorsal pattern in males and females. We provide a cranial osteological description and a phylogenetic analysis of the new species. This discovery brings the number of recognized Dixonius species to 19, among them nine species endemic to Thailand.
New species and new records of Glyptoma Erichson, 1839 (Coleoptera: Staphylinidae)
Authors: KLEMANN-JUNIOR LOURI , MOURA ROBERTA SOUZA DE , IRMLER ULRICH , ASENJO ANGÉLICO
Published: February 2025

We described three new species of the genus Glyptoma Erichson, 1839 (Coleoptera: Staphylinidae: Osoriinae), G. curupira Klemann-Junior, Moura, Irmler & Asenjo, sp. nov., G. luae Klemann-Junior, Moura, Irmler & Asenjo, sp. nov. and G. malkini Irmler, Klemann-Junior, Moura & Asenjo, sp. nov., from Amazonas and Pará states, in the north of Brazil. We illustrated major diagnostic features and integrated the new species into the key to Glyptoma species published by Irmler (2015). Furthermore, we provided new records of G. amazonense Irmler 2015, G. denieri (Bernhauer 1939), G. klimschi (Bernhauer 1908), G. lescheni Irmler 2015, and G. nitidum (Bernhauer 1908) for Brazil, and G. cicatricosa Motschulsky 1857 for French Guiana.
Taxonomy of the West Palaearctic butterfly genus Palaeophilotes Forster, 1938 (Lepidoptera: Lycaenidae) based on combined analysis of COI barcodes and multilocus nuclear markers
Authors: LUKHTANOV VLADIMIR A. , MAKHOV ILYA A. , GAGARINA ANASTASIA V. , ROMANOVICH ANNA E.
Published: February 2025

Based on molecular phylogenetic analysis of all relevant taxa, we propose to consider the species previously classified as members of Pseudophilotes, Palaeophilotes, Rubrapterus, and Inderskia as belonging to a single genus, the valid name of which is Palaeophilotes. This genus can be divided into two subgenera: Rubrapterus with species P. bavius and P. fatma, and Palaeophilotes sensu stricto. The latter subgenus includes four lineages and nine species: (1) the P. abencerragus lineage (single species P. abencerragus), (2) P. barbagiae lineage (single species P. barbagiae), (3) P. panope lineage (P. panope and P. triphysina), and (4) P. baton lineage (P. panoptes, P. baton, P. vicrama, P. jacuticus and P. sinaicus). The name Borisinia Korb, 2013, syn. nov. is shown to be an objective synonym of Palaeophilotes Forster, 1938. The previously proposed synonymy of P. svetlana and P. marina with P. panope is supported by the identity of their DNA-barcodes. Palaeophilotes panope is reported for the Kazakhstan part of the Altai mountains for the first time. Palaeophilotes jacuticus is confirmed for the Lake Baikal region in Siberia.
5. Epistemological assumptions in phenomenography
Authors: S. Åkerlind Gerlese
Published: February 2025

As described in Chapter 2, phenomenography developed from a research approach that was based on a common object of study in the 1980s, to a research approach with an accompanying set of accepted methods in the 1990s, to a research methodology with associated ontological and epistemological assumptions in the 2000s. This last development was initiated by the publication of Marton and Booth’s (1997) book, Learning and Awareness, in particular. This means that, from the 2000s, anyone who attempts to undertake phenomenographic research simply by applying a set of accepted methods, without an accompanying understanding of the theoretical assumptions underpinning those methods, will be short-changing their research. Chapter 5 describes the key epistemological assumptions put forward in Learning and Awareness, and clarifies how they relate to the methods adopted in phenomenography.
6. Study design, data gathering and the phenomenographic interview
Authors: S. Åkerlind Gerlese
Published: February 2025

Interviews are the traditional source of empirical data for phenomenographic research. But the phenomenographic interview is quite distinctive in nature. Phenomenographic interviews have a particular focus on working from concrete examples of participants’ interactions with the phenomenon under investigation, and seeking in-depth reflections from participants on why they interacted with the phenomenon in those particular ways. Participants are not expected to be able to describe their experience of a phenomenon directly, but to demonstrate that experience indirectly, through the ways in which they interact with the phenomenon. This chapter explains the design and conduct of interviews, illustrating the key principles with extended concrete examples from my own and others’ research. Although the focus of the chapter is on interviews, key principles for other forms of phenomenographic data gathering are also clarified.
Where Global Warming Meets Local Decision-Making: An Introduction to the Arctic Science Policy Landscape
Authors: Miller Andy
Published: February 2025

The Arctic is one of the fastest warming places on Earth. The consequences of this warming are already felt locally and globally and are expected to intensify over the next few decades. As a result, there is great need for scientists to inform the many policy decisions related to weather, water, and climate (WWC) in the Arctic. This study aims to 1) give an overview of the most prominent organizations involved in Arctic science policy, 2) introduce the most discussed policy issues in the Arctic and how they connect to weather, water, and climate science, and 3) discuss how scientists and policymakers can collaborate with Indigenous peoples to achieve outcomes that better align with interests at all levels of decision making from international to individual communities.
Idealized Simulations of Supercell Thunderstorms Traversing the Appalachian Mountains
Authors: Riggin Roger R. , Davenport Casey E. , Eastin Matthew D. , McKeown Katherine E. , Purpura Sarah M. , Katona Branden T.
Published: February 2025

Substantial short-term forecasting challenges arise when supercell thunderstorms traverse through regions of complex terrain, such as the central and southern Appalachian Mountains. Prior work has documented the environmental and radar characteristics of supercells that cross or fail to cross complex terrain throughout this region. The current work builds upon these prior studies by conducting a series of high-resolution idealized simulations to further investigate how the terrain of the Appalachian Mountains impacts discrete supercell thunderstorms. Emphasis is placed on quantifying influences due to physical airflow over the mountains versus localized terrain-induced environmental heterogeneities experienced by storms. Nine sensitivity experiments, rooted in prior observational work, explored how orographic features act to modulate the inflow environment as well as storm-scale morphology. The model’s background field was either horizontally homogeneous and fixed over time (Steady-State) or systematically allowed to evolve via Base-State Substitution (Variable-State). Three different frictionless lower-boundary conditions were tested, including no terrain, idealized terrain, and realistic terrain. Results effectively highlighted four key terrain-induced processes (i.e., Blocking, Channeling, Upslope Flow, and Downslope Flow) that modulate supercells at both the meso-γ and meso-β scales. A series of conceptual models were constructed to summarize the impacts these processes may present on supercells in real-time. In short, terrain influences resulting in low-level kinematic enhancements are crucial for supercellular maintenance while traversing regions of complex terrain.
Understanding the Water Landscape of the United States
Authors: Seid-Green Ya'el
Published: February 2025

There is an ongoing national dialogue on water, which has produced a vast number of reports, studies, and analyses containing hundreds, if not thousands, of recommendations for water science and policy. There is great opportunity in understanding the assessments and recommendations that have come before, in order to inform the future – we can build on existing knowledge, and identify common priorities and unmet needs. A review of thirty reports on hydrologic science and management reveals twelve common recommendations and six topics that are not well covered in the national dialogue on water.
The Effect of Anger Rumination on Malevolent Creativity: The Mediating Role of Aggression and the Moderating Role of Mindfulness
Authors: Zhang Meng yue , Guo Han , Gong Zhe
Published: February 2025

Malevolent creativity, as a kind of harmful creativity, can seriously threaten social stability and can have profound negative impacts on society. Uncovering the influencing factors and mechanisms of malevolent creativity helps individuals understand its nature and characteristics, providing research support for preventing and controlling malevolent creativity events. This cross-sectional study is based on the generation process of thoughtful action in the General Aggression Model (GAM) to think about the mechanism of malevolent creativity. The study took 383 Chinese college students (76.2% female, Mage = 20.18, SD = 2.22 years) as a representative sample to examine the impact of angry rumination on malevolent creativity. In addition, this study tested a relational model incorporating angry rumination, mindfulness, aggression, and malevolent creativity. The results indicated that anger rumination not only directly predicts malevolent creativity, but also indirectly influences malevolent creativity through the partial mediating effect of aggression. More importantly, this study found an interesting result that mindfulness moderates the impact of anger rumination on aggression after controlling for gender, age, and education level. Specifically, high levels of mindfulness facilitated the mediating effect of angry rumination on aggression, thereby enhancing levels of malevolent creativity. In other words, instead of suppressing, mindfulness can intensify the path from angry rumination to aggression, a finding that conflicts with the view of mindfulness as a protective factor in previous studies. This study theoretically enriches the research on the influencing factors of malevolent creativity and helps to better understand the mechanism of malevolent creativity. It also has certain practical significance, providing some inspiration for the intervention of malevolent creativity under the theoretical framework of GAM.
Injury Epidemiology and Risk Factors in Older Pickleball Players
Authors: Kim Kyung-Min , Ryu Jungsu , Nam Seung-Hee , Hyung Kim Amy Chan , Lee Chungsup , Heo Jinmoo
Published: February 2025

This study aimed to identify pickleball-related injury prevalence and risk factors in older adults and evaluate injury incidence during a pickleball tournament. A cross-sectional study analyzed self-reported injuries from the past 12 months and new injuries during the 2018 US Open Pickleball Championships. Data were collected on demographics, play characteristics, and psychological attributes. Injury details came from self-reports and medical tent records. Hierarchical logistic regression identified significant injury predictors. Of 237 participants, 32.1% reported past-year injuries, mainly in lower extremities (57.9%) and muscle/tendon tissues (61.8%). The tournament had a 5.8% incidence of new injuries, primarily in lower extremities and skin/muscle tissues. Key risk factors were male gender, lower BMI, and increased weekly play hours. No significant associations were found with psychological variables. Pickleball players have a high injury prevalence, especially in lower extremities, linked to longer play hours, male gender, and lower BMI.
Why and When Do Narcissists Aggress Celebrities Online? Investigating Relative Deprivation and Empathic Self-Efficacy as Potential Mechanisms
Authors: Rong Kexin , Chu Xiaowei
Published: February 2025

In the era of advanced Internet technology, people have more and more opportunities to attack online celebrities through the Internet media. This not only hurts celebrities but subtly and gradually distorts public outlooks on the world and values. However, few studies have explored why and when narcissism is related to online celebrity aggression. The study focused on the relationship between narcissism and online celebrity aggression and the roles of relative deprivation and empathic selfefficacy. A total of 832 participants (female: 28.85%) aged from 17 to 25 years completed the questionnaire. The study found that relative deprivation mediated the relationship between narcissism and online celebrity aggression. Empathic self-efficacy buffered the relationship between narcissism and relative deprivation. The findings reveal the relationship between narcissism and online celebrity aggression and the underlying mechanisms, which enrich the related research in the field of cyberaggression and have some reference value for the intervention of cyberaggression.
Research progress on intervertebral disc repair strategies and mechanisms based on hydrogel
Authors: Hua Zekun , Zhao Yinuo , Zhang Meng , Wang Yanqin , Feng Haoyu , Wei Xiaochun , Wu Xiaogang , Chen Weiyi , Xue Yanru
Published: February 2025

Intervertebral disc degeneration (IDD) arises from a complex interplay of genetic, environmental, and age-related factors, culminating in a spectrum of low back pain (LBP) disorders that exert significant societal and economic impact. The present therapeutic landscape for IDD poses formidable clinical hurdles, necessitating the exploration of innovative treatment modalities. The hydrogel, as a biomaterial, exhibits superior biocompatibility compared to other biomaterials such as bioceramics and bio-metal materials. It also demonstrates mechanical properties closer to those of natural intervertebral discs (IVDs) and favorable biodegradability conducive to IVD regeneration. Therefore, it has emerged as a promising candidate material in the field of regenerative medicine and tissue engineering for treating IDD. Hydrogels have made significant strides in the field of IDD treatment. Particularly, injectable hydrogels not only provide mechanical support but also enable controlled release of bioactive molecules, playing a crucial role in mitigating inflammation and promoting extracellular matrix (ECM) regeneration. Furthermore, the ability of injectable hydrogels to achieve minimally invasive implantation helps minimize tissue damage. This article initially provides a concise exposition of the structure and function of IVD, the progression of IDD, and delineates extant clinical interventions for IDD. Subsequently, it categorizes hydrogels, encapsulates recent advancements in biomaterials and cellular therapies, and delves into the mechanisms through which hydrogels foster disc regeneration. Ultimately, the article deliberates on the prospects and challenges attendant to hydrogel therapy for IDD.
Not hollowed by a Delphic frenzy: European intermediary liability from the perspective of a bad man: A response to Martin Husovec et al.
Authors: FitzGerald Michael
Published: February 2025

This article applies Oliver Wendell Holmes's heuristic device of the ‘bad man’ to the context of ECtHR intermediary liability jurisprudence. Holmes asserts: ‘if you want to know the law and nothing else’, you must look at it from the perspective of a ‘bad man’. In a June 2024 Issue of the Maastricht Journal, Martin Husovec et al. claim that this ECtHR jurisprudence has ‘officially descended into chaos’ since the 2023 judgment of Sanchez v. France. According to Husovec, Sanchez upended the Court's prior case law and overturned the landmark precedent of Delfi v. Estonia. This article produces a different conclusion. This conclusion is as follows: Sanchez does not overturn Delfi. Instead, Sanchez confirms Delfi. Thus, contrary to Husovec's view that the ECtHR is ‘at risk’ of colliding with EU law, this article proposes that the collision has already occurred, and that Europe's two highest courts have been in a state of ‘collision’ – espousing irreconcilable doctrine – for almost a decade. The fact that this collision has been invisible to scholarship, the article concludes, ought to encourage reflection upon the efficacy of doctrinal analysis of the highest European courts as a method for observing the actual downstream effects of major judgments like Delfi and Sanchez.
How Do University Students Navigate Distress? An Examination of Determinants, Coping Strategies, and Support Systems Through the Lens of Self-Determination Theory
Authors: Hernández-Torrano Daniel , Ibrayeva Laura
Published: February 2025

Entrance to university is marked by significant changes and challenges that can impact mental health and well-being. This study investigated the determinants of psychological distress, coping strategies used, and the availability of support systems among university students in a non-Western country through the lenses of self-determination theory. The thematic analysis of 16 in-depth interviews revealed several academic, socio-demographic, and situational factors crucial in facilitating or impeding university students’ sense of self-determination and, consequently, their psychological distress. The study uncovered students’ relative preference for avoidance coping mechanisms, the limited presence of perceived formal support systems in higher education institutions, and a clear reliance of students on informal sources of support to buffer the effects of distress. Moreover, it was evident that students perceived their higher education settings as leaning toward being controlling rather than autonomy-supportive. Implications for promoting well-being among university students are discussed.