bluuebunny/crossref_metadata_2025 huggingface dataset:
Live imaging of alterations in cellular morphology and organelles during cornification using an epidermal equivalent model
Authors: Ipponjima Sari , Umino Yuki , Nagayama Masaharu , Denda Mitsuhiro
Published: March 2020

The stratum corneum plays a crucial role in epidermal barrier function. Various changes occur in granular cells at the uppermost stratum granulosum during cornification. To understand the temporal details of this process, we visualized the cell shape and organelles of cornifying keratinocytes in a living human epidermal equivalent model. Three-dimensional time-lapse imaging with a two-photon microscope revealed that the granular cells did not simply flatten but first temporarily expanded in thickness just before flattening during cornification. Moreover, before expansion, intracellular vesicles abruptly stopped moving, and mitochondria were depolarized. When mitochondrial morphology and quantity were assessed, granular cells with fewer, mostly punctate mitochondria tended to transition to corneocytes. Several minutes after flattening, DNA leakage from the nucleus was visualized. We also observed extension of the cell-flattening time induced by the suppression of filaggrin expression. Overall, we successfully visualized the time-course of cornification, which describes temporal relationships between alterations in the transition from granular cells to corneocytes.
Association of immunophenotype with expression of topoisomerase II α and β in adult acute myeloid leukemia
Authors: Michelson Andrew P. , McDonough Shannon , Willman Cheryl L. , Koegle Eric R. , Godwin John E. , Petersdorf Stephen H. , List Alan F. , Othus Megan , Appelbaum Frederick R. , Radich Jerald P. , Ganapathi Mahrukh K. , Advani Anjali S. , Ganapathi Ram N.
Published: March 2020

Anthracyclines used in the treatment of acute myelogenous leukemia (AML) inhibit the activity of the mammalian topoisomerase II (topo II) isoforms, topo II α and topo IIβ. In 230 patients with non-M3 AML who received frontline ara-C/daunorubicin we determined expression of topo IIα and topo IIβ by RT-PCR and its relationship to immunophenotype (IP) and outcomes. Treatment outcomes were analyzed by logistic or Cox regression. In 211 patients, available for analysis, topo IIα expression was significantly lower than topo IIβ (P < 0.0001). In contrast to topo IIα, topo IIβ was significantly associated with blast percentage in marrow or blood (P = 0.0001), CD7 (P = 0.01), CD14 (P < 0.0001) and CD54 (P < 0.0001). Event free survival was worse for CD56-negative compared to CD56-high (HR = 1.9, 95% CI [1.0–3.5], p = 0.04), and overall survival was worse for CD-15 low as compared to CD15-high (HR = 2.2, 95% CI [1.1–4.2], p = 0.02). Ingenuity pathway analysis indicated topo IIβ and immunophenotype markers in a network associated with cell-to-cell signaling, hematological system development/function and inflammatory response. Topo IIβ expression reflects disease biology of highly proliferative disease and distinct IP but does not appear to be an independent variable influencing outcome in adult AML patients treated with anthracycline-based therapy.
Controlling the Multifractal Generating Measures of Complex Networks
Authors: Yang Ruochen , Bogdan Paul
Published: March 2020

Mathematical modelling of real complex networks aims to characterize their architecture and decipher their underlying principles. Self-repeating patterns and multifractality exist in many real-world complex systems such as brain, genetic, geoscience, and social networks. To better comprehend the multifractal behavior in the real networks, we propose the weighted multifractal graph model to characterize the spatiotemporal complexity and heterogeneity encoded in the interaction weights. We provide analytical tools to verify the multifractal properties of the proposed model. By varying the parameters in the initial unit square, the model can reproduce a diverse range of multifractal spectrums with different degrees of symmetry, locations, support and shapes. We estimate and investigate the weighted multifractal graph model corresponding to two real-world complex systems, namely (i) the chromosome interactions of yeast cells in quiescence and in exponential growth, and (ii) the brain networks of cognitively healthy people and patients exhibiting late mild cognitive impairment leading to Alzheimer disease. The analysis of recovered models show that the proposed random graph model provides a novel way to understand the self-similar structure of complex networks and to discriminate different network structures. Additionally, by mapping real complex networks onto multifractal generating measures, it allows us to develop new network design and control strategies, such as the minimal control of multifractal measures of real systems under different functioning conditions or states.
Printable Highly Stable and Superfast Humidity Sensor Based on Two Dimensional Molybdenum Diselenide
Authors: Awais Muhammad , Khan Muhammad Umair , Hassan Arshad , Bae Jinho , Chattha Tahseen Elahi
Published: March 2020

Transition metal dichalcogenides (TMDCs) are promising materials for sensing applications, due to their exceptional high performance in nano-electronics. Inherentely, the chemical and thermal responses of TMDCs are highly stable, hence, they pave way for real time sensor applications. This article proposes inceptively a stable and superfast humidity sensor using two-dimensional (2D) Molybdenum diselenide (MoSe2) through printed technlogies. The 2D MoSe2 ink is synthesized through wet grinding to achieve few-layered nano-flakes. Inter digital electrodes (IDEs) are fabricated via screen-printing on Polyethylene terephthalate (PET) substrate and thin film of MoSe2 nano-flakes is fabricated through spin coating. The impedance and capacitance response are recorded at 1 kHz between temperature levels ranging from 20–30 °C. The impedance and capacitance hysteresis results are recorded <1.98% and <2.36%, respectively, ensuring very good repeatability during humidification and dehumidification. The stability of impedance and capacitance response are recorded with maximum error rate of ~ 0.162% and ~ 0.183%, respectively. The proposed sensor shows fast impedance response time (Tres) of ~ 0.96 s, and recovery time (Trec) of ~ 1.03 s, which has Tres of ~ 1.87 s, and Trec of ~ 2.13 s for capacitance. It is aimed to develop a high performance and stable humidity sensor for various monitoring applications.
Temporal trajectories of accompanying comorbidities in patients with type 2 diabetes: a Korean nationwide observational study
Authors: Jeong Eugene , Park Namgi , Kim Yujeong , Jeon Ja Young , Chung Wou Young , Yoon Dukyong
Published: March 2020

Type 2 diabetes mellitus is a major concern globally and well known for increasing risk of complications. However, diabetes complications often remain undiagnosed and untreated in a large number of high-risk patients. In this study based on claims data collected in South Korea, we aimed to explore the diagnostic progression and sex- and age-related differences among patients with type 2 diabetes using time-considered patterns of the incidence of comorbidities that evolved after a diagnosis of type 2 diabetes. This study compared 164,593 patients who met the full criteria for type 2 diabetes with age group-, sex-, encounter type-, and diagnosis date-matched controls who had not been diagnosed with type 2 diabetes. We identified 76,423 significant trajectories of four diagnoses from the dataset. The top 30 trajectories with the highest average relative risks comprised microvascular, macrovascular, and miscellaneous complications. Compared with the trajectories of male groups, those of female groups included relatively fewer second-order nodes and contained hubs. Moreover, the trajectories of male groups contained diagnoses belonging to various categories. Our trajectories provide additional information about sex- and age-related differences in the risks of complications and identifying sequential relationships between type 2 diabetes and potentially complications.
Dairy Propionibacterium freudenreichii ameliorates acute colitis by stimulating MUC2 expression in intestinal goblet cell in a DSS-induced colitis rat model
Authors: Ma Seongho , Yeom Jiah , Lim Young-Hee
Published: March 2020

An intact mucus layer is important in managing inflammatory bowel disease (IBD). Dairy Propionibacterium freudenreichii has probiotic potential, produces propionic acid and is known to promote health. The aim of this study was to evaluate the effects of P. freudenreichii on the improvement of colitis. LS 174T goblet cells and a dextran sodium sulfate (DSS)-induced colitis rat model were used to investigate the P. freudenreichii-induced stimulation of mucin production in vitro and in vivo, respectively. The mRNA and protein expression levels of MUC2, a main component of intestinal mucus, increased in the supernatant of P. freudenreichii culture (SPFC)-treated LS 174 cells. The SPFC and live P. freudenreichii (LPF) reduced the disease activity index (DAI) in the rats with DSS-induced colitis. After treatment with SPFC or LPF, the mRNA levels of typical pro-inflammatory cytokines decreased and the inflammatory state was histologically improved in the rats with DSS-induced colitis. The SPFC and LPF treatments increased the gene and protein expression levels of MUC2 in the rats with DSS-induced colitis compared with the expression levels in the negative control rats, and immunohistochemistry (IHC) showed an increase of the intestinal MUC2 level. In addition, SPFC and LPF augmented the level of propionate in the faeces of the rats with DSS-induced colitis. In conclusion, P. freudenreichii might improve acute colitis by restoring goblet cell number and stimulating the expression of MUC2 in intestinal goblet cells.
Pre-operative intravitreal dexamethasone implant in patients with refractory diabetic macular edema undergoing cataract surgery
Authors: Kabanarou Stamatina A. , Xirou Tina , Boutouri Eirini , Gkizis Ilias , Vasilias Dimitrios , Bontzos Georgios , Chatziralli Irini
Published: March 2020

To examine preoperative use of intravitreal dexamethasone implant in patients with refractory diabetic macular edema (DME) undergoing cataract surgery. Participants in this study were 17 patients with DME refractory to previous treatment with anti-vascular endothelial growth factor agents or dexamethasone implant, and co-existent cataract. All participants received intravitreal dexamethasone implant at baseline and underwent phacoemulsification within one month after its insertion. Best-corrected visual acuity (BCVA) and central subfield thickness (CST) changes between baseline, time of cataract surgery and postoperative months 1, 2 and 3 were evaluated. At month 1 after surgery, BCVA improved significantly from 42.3 ± 9.6 to 58.7 ± 11.9 letters compared to baseline (p < 0.001) and the improvement was sustained at month 2 and month 3 postoperatively. One month postoperatively, CST improved significantly compared to baseline (p < 0.001) and the improvement was sustained at month 2 (p < 0.001), while at month 3 CST started to increase, but remained significantly lower than baseline (p = 0.003). At month 3 postoperatively, 35.3% of patients presented recurrence of ME. Patients with refractory DME and cataract can safely undergo phacoemulsification when dexamethasone implant is inserted one month prior to surgery to ensure adequate control of postoperative inflammation and prevent deterioration of ME.
An abscisic acid-responsive protein interaction network for sucrose non-fermenting related kinase1 in abiotic stress response
Authors: Carianopol Carina Steliana , Chan Aaron Lorheed , Dong Shaowei , Provart Nicholas J. , Lumba Shelley , Gazzarrini Sonia
Published: March 2020

Yeast Snf1 (Sucrose non-fermenting1), mammalian AMPK (5′ AMP-activated protein kinase) and plant SnRK1 (Snf1-Related Kinase1) are conserved heterotrimeric kinase complexes that re-establish energy homeostasis following stress. The hormone abscisic acid (ABA) plays a crucial role in plant stress response. Activation of SnRK1 or ABA signaling results in overlapping transcriptional changes, suggesting these stress pathways share common targets. To investigate how SnRK1 and ABA interact during stress response in Arabidopsis thaliana, we screened the SnRK1 complex by yeast two-hybrid against a library of proteins encoded by 258 ABA-regulated genes. Here, we identify 125 SnRK1- interacting proteins (SnIPs). Network analysis indicates that a subset of SnIPs form signaling modules in response to abiotic stress. Functional studies show the involvement of SnRK1 and select SnIPs in abiotic stress responses. This targeted study uncovers the largest set of SnRK1 interactors, which can be used to further characterize SnRK1 role in plant survival under stress.
In-plane selective area InSb–Al nanowire quantum networks
Authors: Op het Veld Roy L. M. , Xu Di , Schaller Vanessa , Verheijen Marcel A. , Peters Stan M. E. , Jung Jason , Tong Chuyao , Wang Qingzhen , de Moor Michiel W. A. , Hesselmann Bart , Vermeulen Kiefer , Bommer Jouri D. S. , Sue Lee Joon , Sarikov Andrey , Pendharkar Mihir , Marzegalli Anna , Koelling Sebastian , Kouwenhoven Leo P. , Miglio Leo , Palmstrøm Chris J. , Zhang Hao , Bakkers Erik P. A. M.
Published: March 2020

Strong spin–orbit semiconductor nanowires coupled to a superconductor are predicted to host Majorana zero modes. Exchange (braiding) operations of Majorana modes form the logical gates of a topological quantum computer and require a network of nanowires. Here, we utilize an in-plane selective area growth technique for InSb–Al semiconductor–superconductor nanowire networks. Transport channels, free from extended defects, in InSb nanowire networks are realized on insulating, but heavily mismatched InP (111)B substrates by full relaxation of the lattice mismatch at the nanowire/substrate interface and nucleation of a complete network from a single nucleation site by optimizing the surface diffusion length of the adatoms. Essential quantum transport phenomena for topological quantum computing are demonstrated in these structures including phase-coherence lengths exceeding several micrometers with Aharonov–Bohm oscillations up to five harmonics and a hard superconducting gap accompanied by 2e-periodic Coulomb oscillations with an Al-based Cooper pair island integrated in the nanowire network.
Predicting structure zone diagrams for thin film synthesis by generative machine learning
Authors: Banko Lars , Lysogorskiy Yury , Grochla Dario , Naujoks Dennis , Drautz Ralf , Ludwig Alfred
Published: March 2020

Thin films are ubiquitous in modern technology and highly useful in materials discovery and design. For achieving optimal extrinsic properties, their microstructure needs to be controlled in a multi-parameter space, which usually requires too high a number of experiments to map. Here, we propose to master thin film processing microstructure complexity, and to reduce the cost of microstructure design by joining combinatorial experimentation with generative deep learning models to extract synthesis-composition-microstructure relations. A generative machine learning approach using a conditional generative adversarial network predicts structure zone diagrams. We demonstrate that generative models provide a so far unseen level of quality of generated structure zone diagrams that can be applied for the optimization of chemical composition and processing parameters to achieve a desired microstructure.
Stable immobilized amine sorbents for heavy metal and REE removal from industrial wastewaters
Authors: Wilfong Walter Christopher , Kail Brian W. , Wang Qiuming , Shi Fan , Shipley Greg , Tarka Thomas J. , Gray McMahan L.
Published: March 2020

Stable and immobilized amine sorbents can simultaneously remove/recover cationic and oxyanionic toxic metals plus valuable rare earth elements from industrial and mining effluents prior to discharging into environmental water systems.
Reaction mechanism of low-temperature catalysis by surface protonics in an electric field
Authors: Sekine Yasushi , Manabe Ryo
Published: March 2020

We investigate the mechanism behind the high catalytic activities achieved when combining heterogeneous catalysts and direct current electric fields even under mild conditions (<500 K) with relatively low electrical energy consumption.
Staphylococcus aureus strains exposed to copper indium sulfide quantum dots exhibit increased tolerance to penicillin G, tetracycline and ciprofloxacin
Authors: Lian Zong-Juan , Lin Tian-Yang , Yao Cai-Xia , Su Yi-Long , Liao Sheng-Hua , Wu Sheng-Mei
Published: March 2020

Copper indium sulfide, CuInS2 (CIS), semiconductor nanocrystals have the qualities of low toxicity, high absorption coefficient and near-infrared luminescence, and thus have attracted increasing attention due to their wide prospective applications in various fields.
MnO1.88/R-MnO2/Ti3C2(OH/F)x composite electrodes for high-performance pseudo-supercapacitors prepared from reduced MXenes
Authors: Huang Xinhua , Zhu Xingxing , Luo Shaohong , Li Ru , Rajput Nitul , Chiesa Matteo , Liao Kin , Chan Vincent
Published: March 2020

Mixed-valency MnOx (MnO1.88 and MnO2)/Ti3C2(OH/F)x composites electrode materials were in situ growth of MnOx on the surface of Ti3C2(OH/F)x, where the Ti3C2(OH/F)x acts as both template and reducing agent.
Direct etching at the nanoscale through nanoparticle-directed capillary condensation
Authors: Garín M. , Khoury R. , Martín I. , Johnson E. V.
Published: March 2020

A chemical is delivered with nanoscale precision through vapor phase transport and capillary condensation at points defined by nanoparticles.
Organic-based thermoelectrics
Authors: Lindorf M. , Mazzio K. A. , Pflaum J. , Nielsch K. , Brütting W. , Albrecht M.
Published: March 2020

This review provides a general overview on the recent advances for organic-based thermoelectrics with an emphasis on the most thoroughly investigated material classes and the approaches employed to control their thermoelectric transport properties.
Competitive aptasensor for the ultrasensitive multiplexed detection of cancer biomarkers by fluorescent nanoparticle counting
Authors: Pei Xiaojing , Wu Xi , Xiong Jie , Wang Guohong , Tao Guangyu , Ma Yurou , Li Na
Published: March 2020

Multiplexed detection by fluorescent nanoparticle counting based on competitive mode.
A dual-round signal amplification strategy for colorimetric/photoacoustic/fluorescence triple read-out detection of prostate specific antigen
Authors: Jiang Chao , Huang Yan , He Ting , Huang Peng , Lin Jing
Published: March 2020

A colorimetric/fluorescence/photoacoustic triple read-out detection of prostate specific antigen (PSA) was developed by using a silica coated Au@Ag core–shell nanorod (denoted Au@Ag@SiO2) based enzyme-linked immunosorbent assay (ELISA) system.
Valence tautomerism in a cobalt-verdazyl coordination compound
Authors: Fleming Connor , Chung Dorothy , Ponce Servando , Brook David J. R. , DaRos Jeffrey , Das Raja , Ozarowski Andrew , Stoian Sebastian A.
Published: March 2020

A cobalt bis(verdazyl) compound provides a new example of valence tautomerism in acetonitrile solution though the molecule is trapped in the ‘high energy’ tautomer in the crystalline material.
Systematic coformer contribution to cocrystal stabilization: energy and packing trends
Authors: Mazzeo Paolo P. , Canossa Stefano , Carraro Claudia , Pelagatti Paolo , Bacchi Alessia
Published: March 2020

CSD data mining and energy calculations show that coformer self-interactions might significantly contribute to the packing energy stabilization of cocrystals.
Solvent dynamics play a decisive role in the complex formation of biologically relevant redox proteins
Authors: Adams Ellen M. , Lampret Oliver , König Benedikt , Happe Thomas , Havenith Martina
Published: March 2020

THz absorption spectroscopy reveals that water is a critical factor that governs the transient complex formation of redox proteins. Binding of the substrate creates an entropically favorable complex with bulk-like solvent dynamics.
Effects of temperature on the thermal conductivity of amorphous CaO–SiO2–Al2O3slags: a computational insight
Authors: Wang Zhe , Huang Shuheng , Wen Guanghua , Jiang Wenbo , Chen Fuhang , Tang Ping
Published: March 2020

Amorphous CaO–SiO2–Al2O3(CSA) slags are widely used in the glass, ceramic, cement and metallurgy industries.
Effect of the substituent position on the electrochemical, optical and structural properties of donor–acceptor type acridone derivatives
Authors: Kulszewicz-Bajer Irena , Zagorska Malgorzata , Banasiewicz Marzena , Guńka Piotr A. , Toman Petr , Kozankiewicz Boleslaw , Wiosna-Salyga Gabriela , Pron Adam
Published: March 2020

The electrochemical and fluorescence (TADF) properties of phenoxazine derivatives of acridone are strongly isomerism-sensitive.
Characterisation of the temperature-dependent M1 to R phase transition in W-doped VO2 nanorod aggregates by Rietveld refinement and theoretical modelling
Authors: Miao Lei , Peng Ying , Wang Dianhui , Liang Jihui , Hu Chaohao , Nishibori Eiji , Sun Lixian , Fisher Craig A. J. , Tanemura Sakae
Published: March 2020

Synchrotron XRD Rietveld refinement is combined with first-principles calculations to probe the effect of W doping on the IMT mechanism in VO2 nanorods, providing insights into the connection between atomic-scale phenomena and macro-scale properties.
1,2,4,5-Tetrazine based ligands and complexes
Authors: Stetsiuk Oleh , Abhervé Alexandre , Avarvari Narcis
Published: March 2020

1,2,4,5-Tetrazine based ligands and complexes are reviewed with a special focus on their crystal structures and physical properties.
Hypervalent organoiodine(v) metal–organic frameworks: syntheses, thermal studies and stoichiometric oxidants
Authors: Bryant Macguire R. , Richardson Christopher
Published: March 2020

Hypervalent organoiodine(v) zinc and zirconium metal–organic frameworks are produced post-synthetically and studied for their thermal properties and as recyclable heterogeneous reagent oxidants.
Determining the limiting factor of the electrochemical stability window for PEO-based solid polymer electrolytes: main chain or terminal –OH group?
Authors: Yang Xiaofei , Jiang Ming , Gao Xuejie , Bao Danni , Sun Qian , Holmes Nathaniel , Duan Hui , Mukherjee Sankha , Adair Keegan , Zhao Changtai , Liang Jianwen , Li Weihan , Li Junjie , Liu Yang , Huang Huan , Zhang Li , Lu Shigang , Lu Qingwen , Li Ruying , Singh Chandra Veer , Sun Xueliang
Published: March 2020

Terminal –OH group in PEO-based solid polymer electrolytes is the limiting factor of the electrochemical stability window, replacing it with more stable groups can accelerate the development of high-voltage solid-state batteries.
Correction: 5-Heptadecylresorcinol attenuates oxidative damage and mitochondria-mediated apoptosis through activation of the SIRT3/FOXO3a signaling pathway in neurocytes
Authors: Liu Jie , Wang Yu , Hao Yiming , Wang Zongwei , Yang Zihui , Wang Ziyuan , Wang Jing
Published: March 2020

Correction for ‘5-Heptadecylresorcinol attenuates oxidative damage and mitochondria-mediated apoptosis through activation of the SIRT3/FOXO3a signaling pathway in neurocytes’ by Jie Liu et al., Food Funct., 2020, DOI: 10.1039/c9fo03028j.
Zn(ii) phthalocyanines tetra substituted by aryl and alkyl azides: design, synthesis and optical detection of H2S
Authors: Albakour Mohamad , Zeyrek Ongun Merve , Topal Sevinc Zehra , Gürek Ayşe Gül
Published: March 2020

Experimental examination of two novel Zn(ii)-phthalocyanines having aryl and alkyl azide functional groups at the peripheral positions that have been designed/synthesized for hydrogen sulfide (H2S) sensing purposes.
An electrochromic supercapacitor based on an MOF derived hierarchical-porous NiO film
Authors: Zhou Shengyu , Wang Shen , Zhou Shijin , Xu Hongbo , Zhao Jiupeng , Wang Jing , Li Yao
Published: March 2020

Here, a hierarchical porous NiO film/ITO glass bifunctional electrode has been prepared successfully via growing MOF-74 in situ on ITO, which shows outstanding cycle reversibility, excellent capacitance, and high coloration efficiency.
Free-base porphyrins with localized NH protons. Can substituents alone stabilize the elusive cis tautomer?
Authors: Thomas Kolle E. , Conradie Jeanet , Beavers Christine M. , Ghosh Abhik
Published: March 2020

The localization of central NH protons in antipodally tetrasubstituted tetraphenylporphyrins suggested that suitable substitutions might also stabilize a porphyrin cis tautomer, a possibility that appears to be supported by DFT calculations.
The ruthenium(ii)-catalyzed C–H olefination of indoles with alkynes: the facile construction of tetrasubstituted alkenes under aqueous conditions
Authors: Li Ming , Yao Tian-Yu , Sun Sheng-Zheng , Yan Ting-Xun , Wen Li-Rong , Zhang Lin-Bao
Published: March 2020

An environmentally-friendly and facile protocol for the construction of tetrasubstituted alkenes has been established with Ru(ii)-catalyzed C–H bond functionalizations under mild conditions.
Chiral diene-promoted room temperature conjugate arylation: highly enantioselective synthesis of substituted chiral phenylalanine derivatives and α,α-di(arylmethyl)acetates
Authors: Chen Jian-Ping , Xu Ming-Hua
Published: March 2020

A highly enantiocontrolled room temperature rhodium-catalyzed conjugate arylation process for practical synthesis of enantioenriched phenylalanine derivatives and α,α-di(arylmethyl)acetates is described.
Mechanical activation of polymers containing two adjacent mechanophores
Authors: Stevenson Richard , Zhang Min , De Bo Guillaume
Published: March 2020

Polymers containing two adjacent mechanophores cleave at the same as a single-mechanophore chains.
The importance of sulfonate to the self-doping mechanism of the water-soluble conjugated polyelectrolyte PCPDTBT-SO3K
Authors: Cao David Xi , Leifert Dirk , Brus Viktor V. , Wong Matthew S. , Phan Hung , Yurash Brett , Koch Norbert , Bazan Guillermo C. , Nguyen Thuc-Quyen
Published: March 2020

In-depth understanding of the doped and de-doped states of CPE-K, a unique, water-soluble, highly conductive polymer.
Halogen-directed chemical sialylation: pseudo-stereodivergent access to marine ganglioside epitopes
Authors: Hayashi Taiki , Axer Alexander , Kehr Gerald , Bergander Klaus , Gilmour Ryan
Published: March 2020

Sialic acids are conspicuous structural components of the complex gangliosides that regulate cellular processes.
Photothermocatalysis for efficient abatement of CO and VOCs
Authors: Li Yuanzhi , Wu Shaowen , Wu Jichun , Hu Qianqian , Zhou Chongyang
Published: March 2020

Nanostructured metal oxides and their nanocomposites exhibit highly efficient catalytic activity and excellent durability for photothermocatalytic abatement of air pollutants.
Nitrogen fixation on metal-free SiC(111) polar surfaces
Authors: Zheng Mei , Li Yi , Ding Kaining , Zhang Yongfan , Chen Wenkai , Lin Wei
Published: March 2020

Polar SiC(111) is a promising metal-free photocatalyst for nitrogen fixation with excellent selectivity and efficiency.
Facile synthesis and microstructure modulation of crystalline polymeric carbon nitride for highly boosted photocatalytic hydrogen evolution
Authors: Wang Wenbin , Shu Zhu , Zhou Jun , Meng Dawei , Zhao Zhengliang , Li Tiantian
Published: March 2020

Synchronous construction and microstructure-modulation of crystalline PCN were achieved via a facile vapor-deposition method.
Cumulative charging behavior of water droplet driven freestanding triboelectric nanogenerators toward hydrodynamic energy harvesting
Authors: Zhao Leilei , Liu Liqiang , Yang Xiya , Hong Hongxin , Yang Qianming , Wang Jianwei , Tang Qunwei
Published: March 2020

A maximum power density of 1.838 W m−2 is achieved and 30 LEDs can be lighted up by the cumulative water droplets driven freestanding triboelectric nanogenerator demonstrating the great potential for hydrodynamic energy harvesting from rain.
Graphene oxide membranes: controlling their transport pathways
Authors: Su Pengcheng , Wang Fei , Li Zhanjun , Tang Chuyang Y. , Li Wanbin
Published: March 2020

This review presents and discusses the remarkable progress of GO membranes, especially the strategies and mechanisms for controlling their transport pathways in liquid separation.
Photochromic fluorescence switching in liquid crystalline polynorbornenes with α-cyanostilbene side-chains
Authors: Wu Yijin , Zhang Shasha , Pei Jiwei , Chen Xiao-Fang
Published: March 2020

Photoinduced fluorescence colour change based on Z/E isomerization and [2+2] dimerization in cyanostilbene liquid crystalline polymers.
Complement family member CFI polymorphisms and AMD susceptibility from a comprehensive analysis
Authors: Yu Qianqian , Zhu Jing , Yao Yong , Sun Chao
Published: March 2020

The complement factor I (CFI) gene polymorphisms have been reported to age-related macular degenerative (AMD) risk, nevertheless, above association is not consistent. We investigated a meta-analysis to evaluate the conclusions between CFI polymorphisms (rs10033900 and rs2285714) and AMD risk. An identification was covered with the PubMed and other databases through February 8, 2020. Odds ratios (OR) and 95% confidence intervals (CI) were used to assess the strength of associations. After a comprehensive search, 11 different articles (12 case–control studies for total AMD and 11 case–control studies about neovascular disease/geographic atrophy in AMD) were retrieved. Individuals carrying C-allele or CC genotype of rs10033900 polymorphism may have a decreased risk to be AMD disease. For example, there has a significantly decreased relationship between rs10033900 polymorphism and AMD both in the whole group, Caucasian population and population-based source of control. Moreover, a similar trend in subgroup of genotype method group by MALDI-TOF MS was detected. To classify the type of AMD in further, decreased association was also observed in both neovascular disease and geographic atrophy AMD. No association was found about rs2285714 polymorphism. Our present groundbreaking study suggests that the CFI rs10033900 polymorphism is potentially associated with the risk of AMD development.
The Speaker's Experience of Stuttering: Measuring Spontaneity
Authors: Constantino Christopher Dominick , Eichorn Naomi , Buder Eugene H. , Beck J. Gayle , Manning Walter H.
Published: March 2020

Purpose

This study measures the experience of spontaneous speech in everyday speaking situations. Spontaneity of speech is a novel concept developed to account for the subjective experience of speaking. Spontaneous speech is characterized by little premeditation and effortless production, and it is enjoyable and meaningful. Attention is not directed on the physical production of speech. Spontaneity is intended to be distinct from fluency so that it can be used to describe both stuttered and fluent speech. This is the first study to attempt to measure the concept of spontaneity of speech.

Method

The experience sampling method was used with 44 people who stutter. They were surveyed five times a day for 1 week through their cell phones. They reported on their perceived spontaneity, fluency, and speaking context.

Results

Results indicate that spontaneity and fluency are independent, though correlated, constructs that vary with context. Importantly, an increase in spontaneity significantly decreases the adverse impact of stuttering on people's lives. Fluency did not significantly affect adverse life impact of stuttering.

Conclusion

Findings support a theoretical construct of spontaneity that is distinct from speech fluency and that can inform our views of stuttering and approaches to stuttering treatment.
Integrated energy hub system based on power‐to‐gas and compressed air energy storage technologies in the presence of multiple shiftable loads
Authors: Mirzaei Mohammad Amin , Zare Oskouei Morteza , Mohammadi‐Ivatloo Behnam , Loni Abdolah , Zare Kazem , Marzband Mousa , Shafiee Mahmood
Published: March 2020

Integrated energy carriers in the framework of energy hub system (EHS) have an undeniable role in reducing operating costs and increasing energy efficiency as well as the system's reliability. Nowadays, power‐to‐gas (P2G), as a novel technology, is a great choice to intensify the interdependency between electricity and natural gas networks. The proposed strategy of this study is divided into two parts: (i) a conditional value‐at‐risk‐based stochastic model is presented to determine the optimal day‐ahead scheduling of the EHS with the coordinated operating of P2G storage and tri‐state compressed air energy storage (CAES) system. The main objective of the proposed strategy is to indicate the positive impact of P2G storage and tri‐state CAES on lessening the system uncertainties including electricity market price, power generation of the wind turbine, and even electrical, gas, and thermal demands. (ii) A demand response program focusing on day‐ahead load shifting is applied to the multiple electrical loads according to the load's activity schedule. The proposed strategy is successfully applied to an illustrative example and is solved by general algebraic modeling system software. The obtained results validate the proposed strategy by demonstrating the considerable diminution in the operating cost of the EHS by almost 4.5%.
Multi‐slack power flow for islanded microgrids with radial and meshed topologies
Authors: Natanael Moreira Silva Elson , Barbosa Rodrigues Anselmo , da Guia da Silva Maria
Published: March 2020

This study proposes a new power flow formulation for islanded microgrids. The proposed power flow is based on the effect of the superposition principle and the solution of a small non‐linear subproblem to determine the frequency of the microgrid and the voltage magnitude in the angular reference node in each iteration. These variables are determined by considering the following equations in the non‐linear subproblem: active and reactive power balance equations and specified phase at the angular reference node. The application of the superposition principle allowed to obtain two versions of the proposed technique: one for radial networks − based on the current summation method − and another for meshed networks − based on the Gauss‐Zbus method. Therefore, the iterative framework prosed in this study expands in a simple and integrated way the two most commonly used power flow methods in conventional distribution networks for islanded microgrids. The tests in microgrids with 33, 310 and 1438 nodes showed that the proposed approach has the same accuracy as Newton–Raphson algorithm, but with significantly lower computational cost in large scale microgrids. In addition, the proposed method for island microgrid showed good accuracy and convergence for the most common load models applied in power flow studies of islanded microgrids.
Analysis the influence of corrosion layer on the grounding performance of grounding electrodes
Authors: Zhang Zhanlong , Zou Jing , Dan Yihua , Ye Huarui , Li Yiqiao , Deng Jun
Published: March 2020

The grounding electrode buried in soil is prone to corrosion affected by soil and leakage current. The surface of corroded grounding electrodes is wrapped with corrosion product, which affects the normal current dissipation process and weakens the grounding performance. The accurate analysis of the grounding performance with corrosion layer can lay a solid theoretical basis for the safety of the power system. In this study, the corrosion layer is regarded as a layer of conductive medium between the electrode and soil. The leakage current along the electrode and the charge on the interface are analysed by coupling point matching method with boundary element method. Finally, the leakage current, grounding resistance, ground potential rise (GPR) and the step voltage of the two typical electrodes with corrosion layer are investigated. The results show that the corrosion layer causes the reduction of the leakage current at the end of the electrode and the enhancement of the leakage current in the middle location. Furthermore, the corrosion layer causes the increase of the grounding resistance and GPR, and the decrease of the step voltage. In addition, the influence of the reduced radius on the grounding performance is much smaller than that of the corrosion layer.
Dust and gas content of high-redshift galaxies hosting obscured AGN in the Chandra Deep Field-South
Authors: D’Amato Q. , Gilli R. , Vignali C. , Massardi M. , Pozzi F. , Zamorani G. , Circosta C. , Vito F. , Fritz J. , Cresci G. , Casasola V. , Calura F. , Feltre A. , Manieri V. , Rigopoulou D. , Tozzi P. , Norman C.
Published: March 2020

Context. Obscured active galactic nuclei (AGN) represent a significant fraction of the entire AGN population, especially at high redshift (∼70% at z = 3 − 5). They are often characterized by the presence of large gas and dust reservoirs that are thought to sustain and possibly obscure vigorous star formation processes that make these objects shine at FIR and submillimeter wavelengths. Studying the physical properties of obscured AGN and their host galaxies is crucial to shedding light on the early stages of a massive system lifetime.

Aims. We aim to investigate the contribution of the interstellar medium (ISM) to the obscuration of quasars in a sample of distant highly star forming galaxies and to unveil their morphological and kinematics properties.

Methods. We exploit Atacama Large Millimeter/submillimeter Array Cycle 4 observations of the continuum (∼2.1 mm) and high-J CO emission of a sample of six X-ray selected, FIR detected galaxies hosting an obscured AGN at zspec >  2.5 in the 7 Ms Chandra Deep Field-South. We measured the masses and sizes of the dust and molecular gas by fitting the images, visibilities, and spectra, and we derived the gas density and column density on the basis of a uniform sphere geometry. Finally, we compared the measured column densities with those derived from the Chandra X-ray spectra.

Results. We detected both the continuum and line emission for three sources for which we measured both the flux density and size. For the undetected sources, we derived an upper limit on the flux density from the root mean square of the images. We found that the detected galaxies are rich in gas and dust (molecular gas mass in the range < 0.5–2.7 × 1010 M⊙ for αCO = 0.8 and up to ∼2 × 1011 M⊙ for αCO = 6.5, and dust mass < 0.9–4.9 × 108 M⊙) and generally compact (gas major axis 2.1–3.0 kpc, dust major axis 1.4–2.7 kpc). The column densities associated with the ISM are on the order of 1023 − 24 cm−2, which is comparable with those derived from the X-ray spectra. For the detected sources we also derived dynamical masses in the range 0.8–3.7 × 1010 M⊙.

Conclusions. We conclude that the ISM of high redshift galaxies can substantially contribute to nuclear obscuration up to the Compton-thick (> 1024 cm−2) regime. In addition, we found that all the detected sources show a velocity gradient reminding one rotating system, even though two of them show peculiar features in their morphology that can be associated with a chaotic, possibly merging, structure.
Absorbed relativistic jets in radio-quiet narrow-line Seyfert 1 galaxies
Authors: Berton M. , Järvelä E. , Crepaldi L. , Lähteenmäki A. , Tornikoski M. , Congiu E. , Kharb P. , Terreran G. , Vietri A.
Published: March 2020

Narrow-line Seyfert 1 (NLS1) galaxies are peculiar active galactic nuclei. Most of them do not show strong radio emission, but seven radio-quiet (or radio-silent) NLS1s have recently been detected flaring multiple times at 37 GHz by the Metsähovi Radio Telescope, indicating relativistic jets in these peculiar sources. We observed them with the Karl G. Jansky Very Large Array (JVLA) in A configuration at 1.6, 5.2, and 9.0 GHz. Our results show that these sources are either extremely faint or not detected in the JVLA bands. At these frequencies, the radio emission from their relativistic jet must be absorbed, either through synchrotron self-absorption as it occurs in gigahertz-peaked sources, or more likely, through free-free absorption by a screen of ionized gas associated with starburst activity or shocks. Our findings cast new shadows on the radio-loudness criterion, which seems to be increasingly frequently a misleading parameter. New high-frequency and high-resolution radio observations are essential to test our hypotheses.
Amélioration des sols par inclusions rigides : le rôle des géosynthétiques dans la plateforme de transfert de charge
Authors: Simon Bruno , Briançon Laurent , Thorel Luc
Published: March 2020

Dans les ouvrages fondés sur sol renforcé par inclusions rigides (IR), le matelas de répartition peut être renforcé par une ou plusieurs nappes horizontales, aptes à résister en traction, pour améliorer son efficacité et optimiser son épaisseur. Ce renforcement basal du matelas n’a été considéré dans les recommandations du projet national ASIRI (2012) que par analogie avec le cas des remblais sur sol non renforcé par inclusions, en dépit des différences qu’entraîne la proximité des têtes d’inclusion. Un développement considérable des projets de renforcement associant IR et nappes géosynthétiques (GSY) est constaté depuis une dizaine d’années, en relation notamment avec les projets de ligne ferroviaire à grande vitesse. L’état de l’art dont il est rendu compte décrit les traits spécifiques du fonctionnement des nappes GSY dans ce type d’ouvrages, en s’appuyant sur les observations faites sur des ouvrages instrumentés, des modèles physiques ou numériques. Cette revue a permis d’identifier les points liés au fonctionnement des nappes GSY sur un sol renforcé par IR, qu’une recherche spécifique doit permettre de mieux appréhender. Ils concernent : le choix du type de produit, la géométrie des nappes, les gains apportés quant à l’efficacité et/ou la pérennité des mécanismes mobilisés, l’influence des charges mobiles, le transfert des efforts entre les différentes couches (remblai ou sol compressible) et les lés individuels, etc… Cet objectif est celui du projet national ASIRI+ qui a été labellisé par le CODOR RAGC en décembre 2018. Les axes de recherche du projet liés aux nappes GSY sont exposés.
Development of junior students’ emotional intelligence in terms of New Ukrainian School: realities and prospects
Authors: Prakhova Svitlana , Makarenkо Natalya , Shumilina Iryna
Published: March 2020

The article presents a theoretical overview of the phenomenon “emotional intelligence” (EQ). The perspectives of different foreign and domestic psychologists on the concept of EQ, its origin and structure are analised. The importance of studying emotional intelligence and the possible ways of its development as a priority of the New Ukrainian School (NUS) are emphasized. The basis of EQ study is determined as the interrelation of the concepts of “emotional “ intellectual”. Certain positive and negative characteristics of advanced emotional intelligence are highlighted. A methodological toolkit for EQ study is developed and presented. Some prospective ways of its development in ontogeny under appropriate conditions are substantiated. There is an algorithm elaborated for the complex consistent work on EQ development.
Design of educational environment for teachers’ professional training
Authors: Balyk Nadiia , Shmyger Galina , Vasylenko Yaroslav , Oleksiuk Vasyl
Published: March 2020

The article analyzes the concept of the educational environment, its components and features of the structure. The concept of educational environment design was introduced. The components of educational environment design for the teachers’ professional training of the Ternopil Volodymyr Hnatiuk National Pedagogical University (TNPU) are described: technological, didactic and social. The features of this environment such as: information saturation and openness, digital transformation, social practices and cooperation are considered. The study of the effectiveness of educational environment for teachers’ professional development was carried out on the basis of TNPU. In total, 432 masters of all specialties of the University participated in this study. The study used the method of expert assessments for statistical processing of results. The study was conducted to determine the level of importance of all indicators of each component of the educational environment design. The results of the study illustrate the significant changes in the technological and social components of the university’s educational environment design, which have a significant impact on the teachers’ professional training.
Mathematical preparation of students for their professional self-realization in modern innovative society
Authors: Astafieva Mariia , Вodnenko Dmytro , Lytvyn Oksana , Proshkin Volodymyr , Zhyltsov Oleksii
Published: March 2020

The article analyzes the problems of mathematical university preparation of specialists in the context of their professional self-realization in the modern labour market. The structure of mathematical competence of students is considered, its most important components are substantively described (the ability to ask and answer questions in and with mathematics, the ability to deal with mathematical language and tools). As a result of the first (ascertaining) stage of pedagogical experiment allowed to establish the level of students’ mathematical competence formation according to the specified structure was established. It is proved that students of both mathematical and non-mathematical majors have poor mathematical knowledge and skills for solving problems that require their complex application, in particular, modeling problems in the context of future professional activity. The basic approaches to formation of mathematical competence of students are substantiated: research-oriented teaching; interdisciplinary approach and practical orientation; use of digital learning environments and related tools. The methods of implementation of these approaches are disclosed in the authors’ elective discipline for the students of mathematical specialty “Methods of formation of students’ mathematical competence for the future successful career”. The continuation of the research will be the introduction of the discipline above to the educational process which contains the next monitoring of future teachers’ readiness to use indicated approaches in their professional activity.
Methods building and printing 3D models historical architectural objects
Authors: Hevko Ihor , Potapchuk Olha , Lutsyk Iryna , Yavorska Viktorya , Tkachuk Viktoriia
Published: March 2020

The authors present methods building and printing three-dimensional models for graphical reconstruction of historical architectural objects. Procedure sequence of the methods is exemplified through building the model of the Parochial Cathedral of St. Mary of the Perpetual Assistance of the 1950s. After analyzing and assessing the most popular specialized software means, the 3DS Max environment is chosen to build a three-dimensional model. Suggested software tools enable increased accuracy, speed and granularity of fixation of complex systems and expanded
databases, providing efficient instruments to deal with bulk data and being relevant to new IT achievements. Sequence and content of operations for analytical and modeling cycles are substantiated. The cathedral model is built on the basis of archive photographs and drafts. The authors describe methods and the algorithm of procedures, principles of architectural and spacious modeling to recreate the architectural object. The three-dimensional model is built by applying a stereogram miniature of the destroyed Cathedral. Reconstruction of spacious configuration of the objects is based on parallax assessment of images. Stages of project implementation are determined. There are described methods of implementing modeling by 3DS Max tools and preparing the model for 3D printing in Cura.