bluuebunny/crossref_metadata_2025 huggingface dataset:
Strengthening the Health Workforce through the ECHO Stages of Participation: Participants’ Perspectives on Key Facilitators and Barriers
Authors: Shimasaki Suzuho , Bishop Erin , Guthrie Michelle , Thomas John F (Fred)
Published: January 2019

Introduction:

Project Extension for Community Health Outcomes (ECHO) was originally developed by the University of New Mexico’s Health Science Center (UNMHSC) to build the capacities of primary-care providers and to increase specialty-care access to rural and underserved populations. ECHO Colorado, a replication site at the University of Colorado Anschutz Medical Campus (CUAMC), was developed with the same purpose and to help build the health workforce of Colorado. The CUAMC and its community-based partners recognized that by reducing unnecessary referrals to the medical campus and building primary-care capacity in communities, both would increase their scope and expand overall capacity. This study examines the key factors that influence participant engagement, how participants value the ECHO experience, and the utility of the ECHO Colorado experience according to participants.

Methods:

This study used a mixed-methods approach including 42 interviews and 34 completed surveys. Transcribed interview recordings were coded in NVivo 11, and codes were queried in NVivo and Excel to identify key themes. Survey responses were analyzed in SPSS. Data were examined between and across four attendance groups and triangulated to assess the reliability of the data and validity of overall findings.

Findings:

Key factors increasing registrant engagement included relevant and practical curriculum content; strong and supportive relationships among learners, ECHO faculty, and workplace colleagues; and innovative learning approaches that included opportunities for active, virtual participation through technology, participant management activities, and ECHO’s unique curriculum design.

Conclusion:

Findings from this study validated many of the important elements of ECHO Colorado that make it unique from other iterations of the model being implemented nationally and internationally and identified participant-driven strategies for further amplifying its impact.
The von Willebrand factor D′D3 assembly and structural principles for factor VIII binding and concatemer biogenesis
Authors: Dong Xianchi , Leksa Nina C. , Chhabra Ekta Seth , Arndt Joseph W. , Lu Qi , Knockenhauer Kevin E. , Peters Robert T. , Springer Timothy A.
Published: January 2019

D assemblies make up half of the von Willebrand factor (VWF), yet are of unknown structure. D1 and D2 in the prodomain and D′D3 in mature VWF at Golgi pH form helical VWF tubules in Weibel Palade bodies and template dimerization of D3 through disulfides to form ultralong VWF concatemers. D′D3 forms the binding site for factor VIII. The crystal structure of monomeric D′D3 with cysteine residues required for dimerization mutated to alanine was determined at an endoplasmic reticulum (ER)-like pH. The smaller C8-3, TIL3 (trypsin inhibitor-like 3), and E3 modules pack through specific interfaces as they wind around the larger, N-terminal, Ca2+-binding von Willebrand D domain (VWD) 3 module to form a wedge shape. D′ with its TIL′ and E′ modules projects away from D3. The 2 mutated cysteines implicated in D3 dimerization are buried, providing a mechanism for protecting them against premature disulfide linkage in the ER, where intrachain disulfide linkages are formed. D3 dimerization requires co-association with D1 and D2, Ca2+, and Golgi-like acidic pH. Associated structural rearrangements in the C8-3 and TIL3 modules are required to expose cysteine residues for disulfide linkage. Our structure provides insight into many von Willebrand disease mutations, including those that diminish factor VIII binding, which suggest that factor VIII binds not only to the N-terminal TIL′ domain of D′ distal from D3 but also extends across 1 side of D3. The organizing principle for the D3 assembly has implications for other D assemblies and the construction of higher-order, disulfide-linked assemblies in the Golgi in both VWF and mucins.
The podiatric surgery theatre environment in the UK; is it conducive to learning? A quantitative study using the surgical theatre educational environment measure (STEEM)
Authors: Austen Thomas , Otter Simon
Published: January 2019

Background

In 2015 the Health and Care Professions Council (HCPC) reported that annotation of the register for podiatric surgery would improve the way in which risks are currently managed. The academic institutions provide the teaching environment for the ‘learnt’ Diploma in principles of podiatric surgery however the podiatric surgery departments facilitate the production of the next generation of podiatric surgeons. This research aimed to identify the major elements that contribute to the educational environment, and find and utilise a valid assessment tool which could identify discrete areas to be targeted for improvement as well as being used for monitoring of the environment.

Methods

A quantitative study using the Surgical Theatre Educational Environment Measure (STEEM) via an online tool was utilised for podiatrists working within podiatric surgery, podiatric surgical trainees and podiatric surgeons working towards the Certificate of Completion of Podiatric Surgery Training (CCPST) with a view to assessing the educational environment within the podiatric surgical theatre in the UK.

Results

16/33 responses with a response rate of 48.4% the overall STEEM mean score was 122/160. Four subscales included teaching and training, learning opportunities, atmosphere, and workload/supervision/support were measured. The overall mean score of 76.73% suggests the learning environment may be considered satisfactory; however, areas for potential improvement are identifiable. Results reveal strengths such as a non‐discriminatory surgical theatre atmosphere on racial grounds.

Conclusions

Perception was of a very satisfactory ‘Atmosphere’ within the theatre environment and a very satisfactory ‘opportunity to assist’ within the podiatric surgery theatre environment. The STEEM has potential to be applied further as a quality assessment tool whose results could be used to demonstrate part of the HCPC standards.
Pancreatic cancer microenvironment: a current dilemma
Authors: Uzunparmak Burak , Sahin Ibrahim Halil
Published: January 2019

Pancreatic cancer is one of the leading causes of cancer‐related death in the United States and survival outcomes remain dismal despite significant advances in molecular diagnostics and therapeutics in clinical practice. The microenvironment of pancreatic cancer carries unique features with increased desmoplastic reaction and is infiltrated by regulatory T cells and myeloid‐derived suppressor cells which negatively impact the effector immune cells. Current evidence suggests that stellate cell‐induced hypovascular stroma may have direct effects on aggressive behavior of pancreatic cancer. Preclinical studies suggested improvement in drug delivery to cancer cells with stroma modifying agents. However these findings so far have not been confirmed in clinical trials. In this article, we elaborate current‐state‐of‐the science of the pancreatic cancer microenvironment and its impact on molecular behavior of cancer cells, chemotherapy resistance and druggability of stroma elements in combination with other agents to enhance the efficacy of therapeutic approaches.
Studies of the Optical and Sensing Properties of 1,3,5-Triazine-Cored Star-Shaped (D-π)3-A Molecules with Various Amino-Donor-Type Cation Receptors
Authors: Muraoka Hiroki , Sasaki Hikaru , Ogawa Satoshi
Published: January 2019

We newly designed and synthesized two kinds of 1,3,5-triazine-cored star-shaped (D-π)3-A molecules with 1-aza 15-crown 5-ether receptors (TSM-ACE) and dipicolylamino receptors (TSM-DPA), which possess an intramolecular charge transfer (ICT) nature and exhibit ICT-based optical properties (ICT transition absorption and fluorescence from a ICT excited state). Both TSM-ACE and TSM-DPA display proton-induced optical spectral blue-shifts followed by red-shifts depending on their inherent two-step protonation behavior. Furthermore, TSM-ACE displays optical spectral blue-shifts followed by red-shifts upon stepwise complexation of Mg2+, whereas TSM-DPA displays optical spectral blue-shifts upon the complexation of Zn2+. The cation sensing mechanism can be explained as follows: (i) the initial blue shift is caused by the decreased ICT donor abilities of three amino-donor-type receptors (a decrease of the ICT efficiency) upon binding cations, and (ii) the second red shift is caused by an increased acceptor ability of the 1,3,5-triazine core upon binding cations. Consequently, we revealed that TSM-ACE and TSM-DPA with different cation-recognition functionalities serve as a unique optical sensor capable of visual and distinct detection of not only protons but also different kinds of metal ions.
Case Report: Recurrent hypokalemic periodic paralysis associated with distal renal tubular acidosis (type 1) and hypothyroidism secondary to Hashimoto's thyroiditis
Authors: Meregildo-Rodríguez E. Dante , Failoc-Rojas Virgilio E.
Published: January 2019

Background: Hypokalemic periodic paralysis (HypoKPP) is characterized by transient episodes of flaccid muscle weakness. We describe the case of a teenaged boy with HypoKPP and hyperthyroidism due to Hashimoto's thyroiditis with initial manifestation of renal tubular acidosis. This combination is rare and little described previously in men.

Case presentation: A 17-year-old boy was admitted after three days of muscular weakness and paresthesia in the lower limbs with an ascending evolution, leading to prostration. Decreased strength was found in the lower limbs without a defined sensory level, reduced patellar and ankle reflexes. Positive antithyroid antibodies were found. He received hydration treatment, IV potassium and levothyroxine, with which there was a clinical improvement. Other examinations led to the diagnosis of type 1 renal tubular acidosis.

Conclusion: HypoKPP is a rare disorder characterized by acute episodes of muscle weakness. Type 1 renal tubular acidosis can occur as a consequence of thyroiditis, which is explained by the loss of potassium. This combination is unusually rare, and has not been described before in men. The etiopathogenesis of the disease as well as a dynamic explanation of what happened with the patient are discussed in this report.
Factors associated with poor physical performance in older adults of 11 Peruvian high Andean communities
Authors: Urrunaga-Pastor Diego , Runzer-Colmenares Fernando M. , Arones Tania M. , Meza-Cordero Rosario , Taipe-Guizado Silvana , Guralnik Jack M. , Parodi Jose F.
Published: January 2019

Background: Physical performance in the older adult has been extensively studied. However, only a few studies have evaluated physical performance among older adults of high Andean populations and none have studied the factors associated with it. The objective of this study was to evaluate factors associated with poor physical performance by using the Short Physical Performance Battery (SPPB) in older adults living in 11 Peruvian high Andean communities.

Methods: An analytical cross-sectional study was carried out in inhabitants aged 60 or over from 11 high-altitude Andean communities of Peru during 2013-2017. Participants were categorized in two groups according to their SPPB score: poor physical performance (0-6 points) and medium/good physical performance (7-12 points). Additionally, we collected socio-demographic, medical, functional and cognitive assessment information. Poisson regression models were constructed to identify factors associated with poor physical performance. Prevalence ratio (PR) with 95% confidence intervals (95 CI%) are presented.

Results: A total of 407 older adults were studied. The average age was 73.0 ± 6.9 years (range: 60-94 years) and 181 (44.5%) participants had poor physical performance (0-6 points). In the adjusted Poisson regression analysis, the factors associated with poor physical performance were: female gender (PR=1.29; 95%CI: 1.03-1.61), lack of social support (PR=2.10; 95%CI: 1.17-3.76), number of drugs used (PR=1.09; 95%CI: 1.01-1.17), urinary incontinence (PR=1.45; 95%CI: 1.16-1.82), exhaustion (PR=1.35; 95%CI: 1.03-1.75) and cognitive impairment (PR=1.89; 95%CI: 1.40-2.55).

Conclusions: Almost half of the population evaluated had poor physical performance based on the SPPB. Factors that would increase the possibility of suffering from poor physical performance were: female gender, lack of social support, number of drugs used, urinary incontinence, exhaustion and cognitive impairment. Future studies with a larger sample and longitudinal follow-up are needed to design beneficial interventions for the high Andean population.
Inspiration from the “Biggest Loser”: Social Interactions in a Weight Loss Program
Authors: Uetake Kosuke , Yang Nathan
Published: January 2019

We investigate the role of heterogeneous peer effects in encouraging healthy lifestyles. Our analysis revolves around one of the largest and most extensive databases about weight loss that track individual participants’ meeting attendance and progress in a large national weight loss program. The main finding is that, although weight loss among average-performing peers has a negative effect on an individual’s weight loss, the corresponding effect for the top performer among peers is positive. Furthermore, we show that our results are robust to potential issues related to selection into meetings, endogenous peer outcomes, individual unobserved heterogeneity, lagged dependent variables, and contextual effects. Ultimately, these results provide guidance about how the weight loss program should identify role models.
The capital structure of mature French SMEs and impact of the great recession: A dynamic panel data analysis (2002-2010)
Authors: Adair Philippe , Adaskou Mohamed
Published: January 2019

Two main theories of the capital structure are tested upon a balanced panel dataset of 2,370 French SMEs during nine years over the period 2003-2007 and the period 2008-2010, assessing the impact of the 2008 crisis accordingly. Trade-off theory is based on the optimisation of a target debt ratio, whereas pecking order theory argues that decision-making is sequential and that firms prefer internal funding to debt, due to asymmetry of information. Unlike other studies devoted to French SMEs, estimates come from a dynamic panel model (Generalised Method of Moments) applied to mature businesses. Profitability, guarantees upon which access to credit is granted, and trade credit confirm trade-off theory. Relationships between debt and the lagged debt ratio, growth opportunities, credit risk and control over ownership support the pecking order theory, which passes better the tests. Hence, no unified theory of the capital structure has yet emerged.
Thai Canal and Malacca straits: Complementing or competing stratagem for trade development in South East Asia
Authors: Jeevan Jagan , Mohd Salleh Nurul Haqimin , Othman Mohamad Rosni
Published: January 2019

About 94.8 per cent of Malaysian trade is depending on collective inter/intra-regional maritime networks. Straits of Malacca is an important strait and the only strait that connecting Indian Ocean and South China Sea which contributes to the nation’s economic growth significantly. This strait plays a key character to enable the trade connection between east and west of the globe. In average, about 63,000 different types of vessels passing through the strait per year and the number of the vessels keep accelerating every year. Conversely, the introduction of Thai Canal to detour the trade voyage between Indian Ocean to South China Sea is expecting to reduce about three to four days journey time between these two passages. Although the development of this canal is predicted to provide substantial benefits to shipping lines, the grey area or disadvantages change to implications of this canal need to be explored especially on Malaysian trade and infrastructure. Therefore, a qualitative approach has been employed to achieve the aim of this paper. Face-to-face interviews with experts from various agencies had been conducted to gather information on the impact of Thai Canal on Malaysian trade and infrastructure. The outcome of this paper indicates that the implication of Thai Canal reduces the productivity of Malaysian seaports, transformation of seaports in northern region as a major hub of the nation, enforcing equal regional development between west and east coast Malaysia and administering dramatic progress on multimodalism in each state. The outcome of this research is important as an input for the preparation of Malaysian seaport system due to any significant changes in the trade route. Although, the development of Thai Canal reduce the overdependence on Malacca Straits, the impact of this this new canal will affects the trade performance of this region. Hence, this paper is significant to understand the implications that might occur to this nation due to dynamism of maritime logistics.
teatralizzazione dell’io - Il Valzer di Vittorino, vita di un clarinettista che incanta le piazze e perde il senno in seguito a un incidente stradale
Authors: Longo Abele
Published: January 2019

Da una parte il racconto ‘Vittorino’ ( in Ritratti diversi, Ed Insieme, Terlizzi, 2005), in cui Roberto Russo ripercorre la vita di un suo zio: Vittorino Morciano (1918-1990), clarinettista di talento di Montesardo in provincia di Lecce, il maggiore di una famiglia di nove figli, che ritorna traumatizzato dall’esperienza in guerra per poi finire qualche anno dopo in manicomio a causa di un incidente stradale. Dall’altra, un adattamento teatrale che Abele Longo e lo stesso Roberto scrivono insieme e che si propone di fissare i momenti chiave di una vita che si trova ad essere rinchiusa negli stessi riti e bisogni giornalieri, oscillando tra un passato e un presente che finiscono per sovrapporsi.
artas de doña Esperanza.
Authors: Calbarro Juan Luis
Published: January 2019

Basándonos en la experiencia de una maestra aragonesa en Fuerteventura (Islas Canarias) y de su joven alumna allá por los años treinta, y coincidiendo con el clima de la guerra civil española, examinamos las posibilidades de las cartas privadas como vía de apoyo a las tareas educativas, así como la utilidad del medio epistolar en la expresión de la realidad femenina en contextos patriarcales en que su manifestación pública resulta cuando menos difícil.
Avanti il divorzio e La mia vita
Authors: Gragnani Cristina
Published: January 2019

Avanti il divorzio (1902) di Anna Franchi narra della vita di Anna Mirello dall’infanzia ‘libera e gagliarda’ (per dirla con le parole, più tarde, della Aleramo3), attraverso il suo matrimonio – sedicenne – con il musicista Ettore Streno, fino alla partenza del marito per gli Stati Uniti insieme ai figli. Romanziera, drammaturga, biografa, critica e storica d’arte, Anna Franchi nasce a Livorno nel 1867 e muore a Milano nel 1954. Gravitando attorno al Partito Socialista, si impegna per la campagna a favore di una legge sul divorzio con articoli e conferenze (oltre al romanzo Avanti il divorzio di cui mi occupo qui). Porta avanti su vari giornali un’azione di sensibilizzazione delle donne riguardo alla loro condizione e ruolo in società, con particola-re attenzione alla lotta per il suffragio  La narrazione ripercorre le violenze inflitte ad Anna da Ettore (assalti sessuali, gravidanze indesiderate, aggressioni verbali, tradimenti, malattie veneree, false accuse, abusi sui figli e infine la sottrazione dei figli) e si ferma proprio nel 1902 – anno di pubblicazione del libro – con la rinuncia da parte di Anna alla lotta per la tutela dei ragazzi che rimangono, per legge, al marito depravato.
“Introduction” au numéro 10 de Mnemosyne
Authors: Barbalato Beatrice
Published: January 2019

On lira dans ce numéro des études traitant de l’incidence de la catégorie temporelle sur les narrations autobiographiques. Il n’est rien qui articule plus que le temps la vision que nous donnons à notre existence. À travers les verbes, le choix d’une langue, l’organisation du discours, l’importance donnée à la présence ou à l’absence, au visible et à l’invisible, comme la mort, on voit le temps exercer son rôle de maître du jeu.

Plus rarement, l’espace apparaît comme le principe ordinateur d’un récit de vie. La culture occidentale est liée à une conception surtout chronologique, linéaire, même si écrivains, artistes, philosophes, principalement au 20e siècle, ont voulu contraster cette vision.

Chronos, kairos, aion, constituent les trois pivots qui depuis l’antiquité façonnent notre vision dans laquelle inscrire tout événement. À chaque pas nous nous rapportons à cet héritage.
The post-Holocaust memoir
Authors: Karpf Anne
Published: January 2019

The War After (Karpf, 1996), a family memoir about the psycho-social effects of the Holocaust on the children of survivors, attracted considerable attention when first published. 20 years later, Karpf argues, it can be read as an example of post-postmemory. Hirsch (2012) defined postmemory as those memories of the Holocaust that the 'second generation' had of events that shaped their lives but took place before they were born. Post-postmemory, Karpf suggests, is the process whereby such narratives are themselves modified by subsequent events and re-readings brought about by three kinds of time - personal, historical and discursive. Although inevitable, such re-readings run the risk of encouraging Holocaust revisionism and denial. Nevertheless, Karpf claims, they are essential to maintain the post-memoir as a living text.
Freud et Fellini
Authors: Vargau Marina
Published: January 2019

La métaphore archéologique traverse en filigrane la pensée scientifique de Freud qui interprète le travail du psychanalyste en train de reconstruire « ce qui a été oublié » par analogie à celui de l’archéologue. Le travail de Fellini comme cinéaste-archéologue parmi les chronotopes de Rome recoupe le travail du psychanalyste freudien parce que les deux participent, avec des moyens spécifiques, à la reconstruction d’un monde. Dans les deux cas, leur approche archéologique est tributaire de Rome, située au centre de leur démarche épistémologique. Cette rencontre entre Freud, Fellini et Rome suscite des questionnements. Quels liens se tissent entre la ville, son cinéaste par excellence et le père de la psychanalyse ? Quels rapports surgissent dans la ville palimpseste entre l’archéologie et l’inconscient, l’inconscient et la mémoire, la mémoire urbaine et celle personnelle ? Quel rôle jouent le rêve et l’invention dans la reconstruction mnésique et dans l’autofiction scientifique et cinématographique ?
caso de fragmentación discursiva
Authors: Sousa Fernández David R. , Rodriguez Gallardo Ángel
Published: January 2019

El graffiti del antiguo campo de concentración de Camposancos (Pontevedra) muestra una serie incompleta de secuencias discursivas, interesantes para el análisis semiótico de la escritura mural. En este artículo analizamos ciertas características peculiares de estos textos generados en un contexto represivo. Para nuestro análisis, nos centraremos especialmente en los diferentes formatos textuales, en la presencia de varias voces discursivas, en el predominio de la escritura del ‘yo’ y en los efectos del paso del tiempo en la conservación del graffiti. Nosotros defendemos dos ideas: la pérdida física del mensaje y el incremento en las dificultades para recuperar informativamente lo no dicho.
Testimonianze di soldati in trincea tra fiumi di parole e silenzi.
Authors: Caffarena Fabio
Published: January 2019

I soldati che hanno combattuto la Grande Guerra hanno lasciato un immenso patrimonio di testimonianze in grado di raccontare la guerra dall’interno e ‘dal basso’. Si tratta spesso di scritture disseminate di contenuti ‘non detti’ per l’incapacità di esprimersi, per timori di censura, per non preoccupare i parenti o per pudore. Nel suo diario di guerra, compilato nel 1915 prima di morire in combattimento, il giovane tenente Flavio Gioia descrive invece le sue avventure sessuali al fronte, le azioni belliche, non risparmia critiche ai superiori e parla dei suoi soldati con uno stile narrativo, ‘pittorico’, in grado di far vedere al lettore ciò che sta leggendo. Chi è Flavio Gioia e cosa ‘non dice’ il suo diario?
non detto nella diplomazia illuministica
Authors: Tylusińska-Kowalska Anna
Published: January 2019

Jan Chrystian Kamsetzer (1753-1795) di origine tedesco, naturalizzato polacco, il primo architetto di corte dell’ultimo re di Polonia, Stanislao Augusto Poniatowski, inviato in Italia su incarico del sovrano per studiare nel Meridione l’arte antica, racconta questa esperienza in uno scambio di lettere con Marcello Bacciarelli, anch’egli un artista presso la corte di Varsavia. La relazione del viaggio si presenta interesantissima per il fatto che nonostante che si tratti di una corrispondenza professionale, essa non è priva di allusioni che accusano il sovrano per le promesse non mantenute. L'esplicito rispetto dimostrato alla figura del Re e un’autocensura per non far trasparire nemmeno una parola di critica, non impedisce tuttavia che tra le righe si senta il non-detto, la solidarietà nel percepire i difetti del sovrano non espressi, bensì intuiti. Kamsetzer non cela il suo disappunto e l’amarezza per l’avarizia del Re e la noncuranza per i suoi sudditi, anche quelli che potrebbero considerarsi privilegiati.
Le travail de lecture des groupes de lecteurs des archives belges du patrimoine autobiographique
Authors: Meurice Francine
Published: January 2019

Le travail de lecture, fourni par les groupes de lecteurs des archives belges du patrimoine autobiographique lors de la rédaction des échos de lecture convoque plusieurs stratégies d’interprétation. Il serait intéressant de repérer quels sont les modèles de lecture théoriques capables de décrire les stratégies le plus souvent sollicitées et ce, afin de cerner les compétences de ce lecteur qui est inscrit dans le dispositif communicationnel de l’APA comme c-énonciateur de ces écrits du « for-privé ». Ce co-énonciateur se profile aux côtés de l’énonciateur des écrits autobiographiques tantôt comme le guide de la construction de l’éthos, tantôt comme un actant rassemblant plusieurs forces lectrices, tantôt comme un témoin de la pratique scripturale à l’instar du lecteur postulé par la critique génétique, tantôt comme un lecteur intime. Quelques configurations discursives du fonds de l’APA seront proposées pour lire ce dialogue entre ces différentes figures.
L' ouïe en tant que stratégie de construction du récit de soi chez Louis-Ferdinand Céline
Authors: Trovato Loredana
Published: January 2019

Cet article vise à analyser le rôle de l’ouïe dans l’œuvre romanesque de Louis-Ferdinand Céline et ses rapports avec les stratégies de construction du récit de soi. Dès la parution de Voyage au bout de la nuit, l’ouïe a toujours été un des sens les plus utilisés par l’auteur, intervenant soit dans l’interaction dynamique avec l’extérieur (en termes de conflit et/ou de relation symbiotique avec le lecteur/narrataire), soit dans les mécanismes de ‘repère’ intérieur des données du vécu biographique («oto-biographie») qui deviennent «oto-mémoire» et, enfin, «oto-fiction». Comme une sorte d’acte maïeutique, le souvenir auditif qui hante sa tête par ses bruits et ses jacassements sans fin, lui impose l’écriture, c’est-à-dire le passage du réel à la fiction du réel. À travers l’analyse des leitmotivs auditifs de l’œuvre célinienne, on essayera ainsi de déterminer les traits essentiels de sa poétique et l’unicité d’un style qu’il appelle – à raison – «petite musique».
À l’écoute du Perdu
Authors: Gauthier Patricia
Published: January 2019

Dans Boutès, Quignard redit ses liens avec la musique. Boutès incarne l’élan vers la condition originaire que la musique, mieux que l’écriture (?), peut espérer faire retrouver parce que seule elle ‘replonge le corps dans le contenant sonore où il se mouvait’ avant la naissance [Boutès,p.65]. De fait, toute l’œuvre de Quignard retrace la quête de ce Perdu de laquelle s’élève un bios dont le biographique est partout et la biographie nulle part. L’impossibilité de cette autobiographie génériquement identifiée trouve peut-être une expression apaisée permettant de réconcilier musique et écriture dans la confession finale de Boutès.
Monocausale ou réticulaire?
Authors: Chehab May
Published: January 2019

L’article étudie la représentation de l’hérédité dans Le Labyrinthe du monde de Marguerite Yourcenar, qui semble s’identifier à la fatalité (« Cette fillette vieille d’une heure est en tout cas déjà prise, comme dans un filet », Souvenirs pieux). C’est pour peser cette contingence que Yourcenar mène une longue enquête généalogique. Pourtant, elle n’est pas dupe de l’inanité de cette recherche (« il va sans dire que je n’ai pas trouvé les communs dénominateurs cherchés entre ces personnes et moi », ibid.).

C’est que Yourcenar oppose au poids de l’hérédité la légèreté du libre-arbitre : si l’homme ne peut se dérober à son destin, il peut du moins s’y soumettre avec ferveur, suivant l’injonction de Nietzsche. Ainsi, la modélisation traditionnelle de l’arbre généalogique, régie par un rapport déterministe et monocausal, cède le pas à une représentation réticulaire du diagramme généalogique, où les nœuds sont unis par la relation – dans les deux sens du terme – qui unit leurs membres.
Paul Léautaud, le destin comme accomplissement d’un demon
Authors: Denavarre Nicolas
Published: January 2019

« Notre tempérament est notre maître » écrivait Paul Léautaud, retrouvant sans le savoir la maxime d'Héraclite selon laquelle « le tempérament de l'homme est son destin » (Ethos anthropo daimon). Le Daimon de Léautaud (1872-1956), on peut l'appeler « Maurice Boissard », du nom de ce personnage que l'écrivain s'était inventé à 30 ans pour signer ses chroniques dramatiques au Mercure de France, un vieillard narcissique, sarcastique, impitoyable, mélancolique et original préfigurant son propre devenir.

Effets d'annonces, intuitions prophétiques de ce « devenir Boissard », moments de révolte puis de résignations, résurgences d'autres moi possibles notés « dans un coin de journal », sont autant d'étapes consignées par le diariste et témoignant de ce processus implacable d'individuation de son Daimon par lequel Léautaud accomplit son propre destin.
Autobiografismo morte e autorappresentazione Michelangelo Merisi da Caravaggio passando per Francis Bacon
Authors: Oppedisano Francesca Rachele
Published: January 2019

Inizia da un assassinio il destino di un genio, o meglio il suo mito, reinventato quattro secoli più avanti alla luce d’una nuova visione del mondo. L’opera di Caravaggio, infatti, rivive in virtù d’un interesse recente. A cominciare da Roberto Longhi, tra i primi storici dell’arte a riconoscere la straordinarietà del maestro lombardo, l’arte di Caravaggio comincia a riverberare d’un senso altro, comincia ad essere attraversata da quegli incontri postumi con intellettuali, studiosi e poeti del novecento che hanno contribuito a riscrivere la biografia d’un genio inscrivendovi la propria. È dunque anche sulla scorta di queste alleanze che si analizzeranno alcuni aspetti dell’opera di Caravaggio che insiste a ripresentarsi di fronte alla contemporaneità del nostro sguardo con perentoria crudele artaudiana teatralità.
Carmelo Bene
Authors: Viglietti Luisa
Published: January 2019

Un’analisi dell’opera di Carmelo Bene attraverso un idea autobiografica che collega tutto il percosrso artistico, da Nostra Signora dei Turchi al ‘l mal de’ fiori. Ricostruisce un corpo alle opere che frequenta, come per il dottor Frankenstein le sue creazioni tendono a rompere gli equilibri costituiti. I personaggi universali come Amleto, Pinocchio, Macbeth, Achille, Adelchi e Aligi sono anti-eroi per eccellenza, vincolati ad un ideale altro e idealmente alto che Carmelo Bene non gli riconosce mai.
AAA. cerco partner
Authors: Pelillo-Hestermeyer Giulia
Published: January 2019

Gli annunci per la ricerca del partner, pubblicati online o sulla carta stampata, rappresentano una forma molto particolare di autobiografia. Gli inserzionisti, nel presentare se stessi, il proprio partner ideale, e il futuro che immaginano di condividere con questa persona, concentrano in poche righe un buon numero di informazioni, affidando al tempo stesso anche allo stile e alla costruzione retorica del testo, la buona riuscita della ricerca. Un’analisi che tiene conto della stratificazione di significati in questa forma particolare del parlare di sé, evidenzia la tensione tra soggettività e adeguamento a modelli sociali e linguistici, tra originalità e stereotipia, nonché il tentativo degli scriventi, attraverso la costruzione di un’identità più o meno ludica, di interagire in modi diversi con il destino.
Le désoubli de soi
Authors: Ouallet Yves
Published: January 2019

Dans La Règle du jeu, Michel Leiris continue l’entreprise de connaissance de soi commencée dans L’Âge d’homme, afin d’accéder à un moi éthique. Les bifurcations, métamorphosées en biffures, deviennent les signes de cette libération de soi par l’écriture. Mais cette tentative échoue dans la transformation escomptée de soi. On ne se change pas soi-même en immergeant l’éthique dans l’écriture: tel est le destin d’une écriture de soi qui n’est pas une ascèse. Cependant, par l’acte d’écrire, l’écrivain dessine une identité différente de l’identité descriptive qui nous est assignée génétiquement et socialement, identité qui diffère également de l’identité narrative chère à Paul Ricoeur: on peut appeler identité poétique cette manière d’être en dehors de soi dans l’oeuvre créée - identité que la pratique poétique de l’écriture de soi rend de plus en plus visible chez Leiris. Alors peut-être seulement se profile dans l’écriture le désoubli de soi.
Lo scienziato e l’artista
Authors: Arrigo Nino
Published: January 2019

Il saggio che proponiamo prende avvio da alcune esperienze autobiografiche, contenute nel romanzo americano postmoderno. Quella di Holden Caulfield e quella di Henry Chinasky, alter ego di Charles Bukowski in Panino al prosciutto. Entrambi i romanzi sembrano quasi una forma larvata di autobiografia, dove i protagonisti dipingono una sorta di ‘ritratto dell’artista da giovane’. Tanto Holden, quanto Henry, sembrano, infatti, rappresentare la metafora o, meglio, l’archetipo dell’artista.

Alla maniera di Jakov ed Holden, anche sulla scomparsa dello scienziato catanese Ettore Majorana, sembrerebbe allungarsi l’ombra di Ulisse e dell’Ebreo Errante Assuero. In essa i confini tra il reale e l’immaginario, rimarrebbero evanescenti, indeterminati come l’esistenza delle particelle quantistiche. Il mistero della scomparsa andrebbe pertanto ricercato nella realtà paradossale del mito e degli archetipi, piuttosto che in quella lineare e razionale della storia. A sintetizzare la figura dell’artista e quella dello scienziato è - in una straordinaria autobiografia - Edgar Morin.
L’ethos del mutuo trascinamento
Authors: Mesirca Margherita
Published: January 2019

Cet article n'est pas disponible au téléchargement en raison du refus de publication de l'auteur en open access

Il est toutefois disponible à la commande au format papier dans la version complète de la revue sur le site des Presses universitaires de Louvain
Raconter la science
Authors: Barbalato Beatrice
Published: January 2019

Les articles de cette septième livraison de Mnemosyne, o la costruzione del senso, traitent des auto/biographies d’hommes de sciences, de leurs eurêka, de leur ethos.

Les essais s’inscrivent dans quatre grandes lignes directrices : I) la conception de la science et l’expérience directe ; II) l’eurêka ! III) le cinéma et l’image de l’homme de science ; IV) l’interrelation entre humanités et sciences naturelles et mathématiques.

Depuis l’antiquité, une certaine image de l’homme de science prédomine. Intelligence, curiosité, intuition et discipline extrême, tête dans les nuages, sont les caractères paradigmatiques d’Archimède, l’ancêtre des scientifiques. Des autobiographies de scientifiques permettent de comprendre quelle vision ils développent de leur propre vie, souvent soumise à un engagement extreme.
“Introduzione” au numéro 9 de Mnemosyne
Authors: Barbalato Beatrice
Published: January 2019

Comment les idées surgissent-elles ? Comment reconnaître leur originalité ? Quelles sont les circonstances dans lesquelles s’inscrit ce déclic ? Avec quelle rapidité ou quelle lenteur ? Dans quelles circonstances heureuses ou malheureuses ? L’expression « saisir une idée » souligne bien à quel point une idée peut être conçue comme arrivée par hasard, éphémère et miraculeuse.

Pour les sciences mathématiques et naturelles, comme pour l’art en toutes ses expressions, l’acte créatif est raconté selon des conceptions différentes. Kronos, kairos, ou plus rarement aiôn, do-minent dans une vision ou dans l’autre.

On constate que bien des témoignages insistent sur la chance, le fortuit, sur le privilège excep-tionnel d’avoir été touché par la fortuna.
Françoise Sagan
Authors: Giardino Alessandro
Published: January 2019

Parallèlement à la rédaction de ses deux premiers romans Bonjour Tristesse et Un certain sourire, Françoise Sagan écrit des carnets de voyage à la demande de l'éditeur en chef de la revue Elle. Sagan prend alors la route de l’Italie et visite Naples, Capri et Venise. Tout au long de ce parcours littéraire, elle revient sur un mythe créateur remontant à ses lectures de jeunesse, et en particulier aux Illuminations d’Arthur Rimbaud. En retraçant des dynamiques mélancoliques derrière l'insouciance saganesque, nous démontrons dans cet article que l’auteure s’écarte des programmes féministes de son époque, aussi bien que de l’opinion de ceux qui l’ont dépeinte comme une jeune fille superficielle et désabusée. Enfin, une lecture interprétative des trois carnets des voyages servira à établir un parallèle entre les textes de fiction de Sagan et sa psycho-biographie, démontrant aussi la persistance du texte-source de Rimbaud dans l’évolution de son imaginaire.
GMS – Gammadiae Management System: cataloguing and interpretation project of the so-called gammadiae starting from the iconographic evidences in the Roman catacombs
Authors: Cumbo Cristina , Cumbo Fabio
Published: January 2019

In the Early Christian catacombs of Rome, the use of the so-called gammadiae was pretty common. Unfortunately, at the daily state of the art, the comprehension of these symbols is still object of discussion for the international research community. In this paper we present the Gammadiae Management System (GMS), a database developed to study and comprehend the meaning of the so-called gammadiae represented on the pallium of saint characters in Early Christian catacombs of Rome. The cataloguing process has been useful to understand a particular symbolism used in the Antiquity, since the 1st century A.D. in the Jewish textile evidences, till the Dura Europos synagogue frescoes and, also, in some profane evidences, such as mosaics or precious gems. The so-called gammadiae seem to indicate the authority and the moral qualities of the men and, rarely, women who wear the pallium. At the moment, the GMS contains 209 forms about the so-called gammadiae in the Roman catacombs, realised in various techniques and on different supports.
Faktor Risiko Penyakit Ginjal Kronik Diabetes (PGK-DM) pada Diabetes Mellitus Tipe-2 (Studi di RSUD DR Soedarso Kota Pontianak Provinsi Kalimantan Barat)
Authors: Rini Sulistio , Hadisaputro Suharyo , Lestariningsih Lestariningsih , Nugroho Heri , Budijitno Selamat
Published: January 2019

Background: Prevalence of type-2 diabetes mellitus have increased signiﬁcantly. The increasing number of people with diabetes has a major impact on the development of chronic diabetic kidney disease. The research was aimed to clarify several risk factors of chronic diabetic kidney disease on type-2 diabetes mellitus (CDK-DM).Method: The research was based on case control study design. The number of respondents was 140 respondents consisting 70 cases and 70 controls that met the criteria of inclusion and exclusion. The cases were patients with type-2 chronic diabetic kidney disease stadium 2-5. The controls were patients with type-2 chronic diabetic kidney disease with blood sugar levels ≥ 200 mg / dL. The data were then analyzed using logistic regression.Results: The result shows that risk factors of chronic diabetic kidney disease in type-2 diabetes mellitus are diabetes in family (OR = 6,732; 95% CI = 2,623- 17,276), high blood pressure (OR = 6,760; 95% CI = 2,190- 20,867), lack of physical activities (OR = 4,367 95% CI = 1,823-10,462) and lack of family support (OR = 4,203; 95% CI = 1,437-12,295). The probability of chronic diabetic kidney disease occurrence in type-2 diabetes mellitus when four risk factors exist are 96,71%.Conclusion: The host factors have important role of chronic diabetic kidney disease in type 2 diabetes mellitus . The factors proven to be risk factors for occurrence of chronic diabetic kidney disease in type 2 diabetes mellitus were diabetic in the family, Hipertension, poor physical exercise and family Support.
Faktor yang Berpengaruh terhadap Kegagalan Pengendalian Diabetes Melitus Tipe 2 pada Pasien yang Berobat di PT. Askes Cabang Sampit Kabupaten Kotawaringin Timur
Authors: Diana Diana , Nugroho Heri , Hadisaputro Suharyo
Published: January 2019

Background: Diabetes mellitus is a chronic disease characterized by blood glucose levels than normal, impaired metabolism of carbohydrates, fats and proteins caused by a deﬁciency of the hormone insulin relative or absolute. Control of blood sugar in people with DMT 2 is an essential requirement for delaying complications, in the community. DMT 2 risk factor is age, long- suffering, sex, education, socio-economic, knowledge, attitudes, practices, patterns of diet, obesity, how to take medication, exercise, family support, educate physicians and nutritionists. The purpose ofthe study describes some of the factors that inﬂuence the DMT2 control failure.Methods: The study used a case-control design is reinforced by the qualitative study. The number of respondents was 122, including 61 cases and 61controls taken by consecutive sampling. Analysis ofthe data using univariate, bivariate (chi-square) and multivariate (logistic regression).Results: Analysis of some factors that inﬂuence the attitude control DMT 2 (OR 34.4), exercise (OR 8.7), knowledge (OR 8,4), age (OR 5.9), family support (OR 5.2), how totake medication (OR 3.5). Various factors were not shown to signiﬁcantly affect the failure to control type 2 diabetes mellitus are: Long suffering, sex, smoking, education, socio-economic, diet, obesity, stress/depression, education of physicians and nutritionists.Conclusion: Several factors were shown to inﬂuence the incidence of DMT 2 control attitude, exercise, knowledge, age, family support, and how to take the medicine.
Berbagai Faktor yang Berpengaruh Terhadap Kejadian Rawat Inap Jemaah Diabetes Melitus di Arab Saudi (Studi Kasus Kontrol di Embarkasi Adisumarmo)
Authors: Nugroho Rakhamanto Wahyu , Hadisaputro Suharyo , Samekto Widiastuti , Sugiri Sugiri , Lukmono Djoko Trihadi
Published: January 2019

Background : Given the magnitude of high-risk DM throughout Hajj embarkation and pilgrims hospitalization in Saudi Arabia, we need for prevention and control of DM pilgrims hospitalization case in Saudi Arabia. To prevent and control the incidence of hospitalization, public and the government needs to know the various factors that influence the incidence of hospitalization.Methods : The study was observational with case control study design. The study population is the assembly of DM in Adisumarmo Hajj embarkation. Number of samples of 135 people with 45 cases and 90 controls. The dependent variable is inpatient diabetic in Saudi Arabia , the independent variable is demographics (age, gender, education level), comorbidities (hypertension, heart disease, dyslipidemia, stroke, obesity), behavior (compliance with diet and medication), the knowledge, long suffered diabetic, environment (temperature and duration in Saudi Arabia.Results : Most respondents had long suffered from diabetes. The level of compliance of respondents to the diet DM and DM medication adherence is good. Multivariate factors that influence the incidence of hospitalization DM pilgrims in Saudi Arabia is a dietary adherence (p=0.001, OR=14,95% CI= 2.78 to 70.97 ) and knowledge (p = 0.003, OR = 6.5; 95% CI=0.59 to 4.51).Conclusion : Factors that influence the incidence of DM pilgrims hospitalization in Saudi Arabia is a dietary adherence and knowledge.
ANALISIS KETIMPANGAN WILAYAH DAN ARAHAN PENGEMBANGAN WILAYAH DI KABUPATEN BURU PROVINSI MALUKU
Authors: Ruman Rifyan , Hadi Setia , Barus Baba
Published: January 2019

The purpose of this study was to determine the class-leading commodity and land capability and potential of land that can be used for agricultural development in Buru. Data analysis method used was overlying maps, Location Quotient (LQ) and Shift Share Analysis (SSA) to determine the main commodity. The result is elaborated as follow inequality in Buru can be seen from inadequate infrastructure especially the condition of road, education and health facilities. Based on analysis of LQ and SSA in the Buru Regency, Commodities priorities in this region are sweet potatoes, peanuts, green beans, peppers, onion, tomato, spinach, kale, squash, eggplant, beans, avocado, mango, jackfruit, durian, orange, papaya, banana, cashew, and clove. The potential cultivate land for each sub-districts as Namlea (22390.73 ha), District Waeapo (68615.62 ha), District of Waplau (22173.26 ha), District Batabual (7920.27 ha) and District Air Buaya (10985.77 ha) that can be utilized for the development of agriculture-based according to the vision of Buru and in accordance with the commodity that exist in each district.
Diagnostic biomarkers of muscle injury and exertional rhabdomyolysis
Authors: Lippi Giuseppe , Schena Federico , Ceriotti Ferruccio
Published: January 2019

Early recognition of muscle injury, up to development of exertional rhabdomyolysis (ER), is essential for many clinical and practical reasons, such as planning the suitable period of recovery and deciding an appropriate time for return to exercise. Albeit magnetic resonance imaging (MRI) remains the reference technique for assessing muscle injuries, and ultrasonography (US) may be a complementary approach for easy, inexpensive and fast screening, the potential drawbacks of both techniques may be overcome by some laboratory tests, which may help guiding both diagnostic reasoning and clinical decision making. Current evidence attest that creatine kinase remains the most validated test across the clinical spectrum of muscles injuries, as its measurement may be helpful for screening subjects with suggestive signs and symptoms, its concentration substantially reflects the amount of injured muscle and its kinetics appears suitable, combined with clinics and results of imaging testing, for making decisions on return to exercise. Relatively low cost and widespread availability are additional advantages of this test. In athletes with ER, myoglobin assessment may provide adjunctive useful information, due to high predictive value for development of acute kidney injury. Regarding other historical biomarkers, namely aldolase and lactate dehydrogenase, the kinetics, correlation with injury severity, laboratory standardization and availability make their measurement unsuitable and redundant. Some innovative biomarkers have also been tested in recent years, including fatty acid-binding proteins and carbonic anhydrase III, myosin light chain 3 and muscle micro RNAs. However, their clinical effectiveness, standardization, availability in clinical laboratories and costs are still regarded as major drawbacks.