bluuebunny/crossref_metadata_2025 huggingface dataset:
Using symbiotic empirical ethics to explore the significance of relationships to clinical ethics: findings from the Reset Ethics research project
Authors: Redhead Caroline A B , Frith Lucy , Chiumento Anna , Fovargue Sara , Draper Heather
Published: October 2023

Background At the beginning of the coronavirus (Covid-19) pandemic, many non-Covid healthcare services were suspended. In April 2020, the Department of Health in England mandated that non-Covid services should resume, alongside the continuing pandemic response. This ‘resetting’ of healthcare services created a unique context in which it became critical to consider how ethical considerations did (and should) underpin decisions about integrating infection control measures into routine healthcare practices. We draw on data collected as part of the ‘NHS Reset Ethics’ project, which explored the everyday ethical challenges of resetting England’s NHS maternity and paediatrics services during the pandemic.Methods Healthcare professionals and members of the public participated in interviews and focus group discussions. The qualitative methods are reported in detail elsewhere [Chiumento, et al. 2023, forthcoming]. The focus of this article is our use of Frith’s symbiotic empirical ethics methodology to work from our empirical findings towards the normative suggestion that clinical ethics should explicitly attend to the importance of relationships in clinical practice. This methodology uses a five-step approach to refine and develop ethical theory based on a naturalist account of ethics that sees practice and theory as symbiotically related.Results The Reset project data showed that changed working practices caused ethical challenges for healthcare professionals, and that infection prevention and control measures represented harmful barriers to the experience of receiving and offering care. For healthcare professionals, offering care as part of a relational interaction was an ethically important dimension of healthcare delivery.Conclusions Our findings suggest that foregrounding the importance of relationships across a hospital community will better promote the ethically important multi-directional expression of caring between healthcare professionals, patients, and their families. We offer two suggestions for making progress towards such a relational approach. First, that there is a change of emphasis in clinical ethics practice to explicitly acknowledge the importance of the relationships (including with their healthcare team) within which the patient is held. Second, that organisational decision-making should take into account the moral significance afforded to caring relationships by healthcare professionals, and the role such relationships can play in the negotiation of ethical challenges.
Optimal scheduling of hydrogen compressed air energy storage including forecast uncertainty
Authors: Klaas Ann-Kathrin , Beck Hans-Peter , Hauer Ines
Published: October 2023

Large-scale energy storage power plants are indispensable for the transition towards a net-zero energy system. The concept of a hydrogen compressed air energy storage (HCAES) power plant combines high storage capacities of hydrogen storage with the high fuel efficiency of diabatic compressed air energy storage. Profitable operation of such a storage power plant can avoid complex governmental incentives. The purpose of this research is the analysis of the effect of forecast limitations and uncertainties on the profitable operation of a hydrogen compressed air energy storage participating in multiple energy markets simultaneously. Implemented methods include a linear programming model with rolling horizon optimization as well as two statistical price forecasting methods. The results show that forecasts with good qualitiy and long forecast horizons are favorable to guarantee profitable operation of the HCAES power plant.
A Hybrid Semantic Recommender System Based on an Improved Clustering
Authors: Bahrani Payam , Minaei-Bidgoli Behrouz , Parvin Hamid , Mirzarezaee Mitra , Keshavarz Ahmad
Published: October 2023

A recommender system is a model that automatically recommends some meaningful cases (such as clips/films/goods/items) to the clients/people/consumers/users according to their (previous) interests. These systems are expected to recommend the items according to the users’ interests. There are two traditional general recommender system models, i.e., Collaborative Filtering Recommender System (ColFRS) and Content-based Filtering Recommender System (ConFRS). Also, there is another model that is a hybrid of those two traditional recommender systems; it is called Hybrid Recommender System (HRS). An HRS usually outperforms simple traditional recommender systems. The problems such as scalability, cold start, and sparsity belong to the main problems that any recommender system should deal with. The memory-based (modeless) recommender systems benefit from good accuracies. But they suffer from a lack of admissible scalability. The model-based recommender systems suffer from a lack of admissible accuracies. But they benefit from good scalability. In this paper, it is tried to propose a hybrid model based on an automatically improved ontology to deal with the scalability, cold start, and sparsity problems. Our proposed HRS also uses an innovative approach of clustering as an augmented section. When there are enough ratings, it uses a collaborative filtering approach to predict the missing ratings. When there are not enough ratings, it uses a content-based filtering approach to predict the missing ratings. In the content-based filtering section of our proposed HRS, ontology concepts are used to improve the accuracy of ratings’ prediction. If our target client is severely sparse, we can not trust even the ratings predicted by the content-based filtering section of our proposed HRS. Therefore, our proposed HRS uses additive clustering to improve the prediction of the missing ratings if the target client is severely sparse. It is experimentally shown that our model outperforms many of the newly developed recommender systems.
Postgraduate year two medical residents' awareness of personal development as a physician during management of inpatients: A qualitative study
Authors: Tokumasu Kazuki , Obara Haruo , Hirosawa Takanobu , Ogawa Hiroko , Otsuka Fumio
Published: October 2023

Background
Physicians need to possess not only clinical knowledge and skills, but also appropriate communication with patients and other healthcare professionals, as well as professionalism. Physicians in training should naturally develop these competencies and should strive to do so. Describing their development process is very important. Previous research has shown that experience, helping relationships and reflection are key to personal development. However, few studies have shown which experiences are important for personal growth and how medical residents specifically use their experiences for personal growth. The aim of this study was to identify from the residents' perspective which clinical experiences contribute to their personal development.
Method
A qualitative study using semi-structured interviews was conducted with Japanese post-graduate year two medical residents working at a teaching hospital. Interviews were transcribed in interview memos, anonymized, and coded inductively. General themes were identified.
Results
Ten medical residents participated in the study. Their ages ranged from 26 to 30 years, five were women and five were men. They had various backgrounds to aspiring departments. Autonomy and responsibility in clinical management were shown to be essential points for personal development as a physician. Autonomy was defined as the attitude of making one's own choices when managing patients. Responsibility is the ability to oblige the resident to take charge of a patient.
Conclusion
Medical residents develop themselves through successful clinical experiences with autonomy in decision-making and a sense of responsibility for patient care. The realization of what experiences and concepts influence medical residents’ personal growth and development will make their personal development more effective. Clinical training for medical residents will be better if the clinical experience with autonomy and responsibility is successfully incorporated within the clinical education setting.
Past-year HIV testing, current antiretroviral therapy use, and participation in services for people who inject drugs
Authors: Sokale Itunu , Wilkerson Johnny , Wermuth Paige Padgett , Burnett Janet , Wejnert Cyprian , Khuwaja Salma , Troisi Catherine
Published: October 2023

Evaluating routine HIV testing and treatment and use of services for people who inject drugs (PWID) is critical to curb the ongoing HIV epidemic. We analyzed data from the 2018 National HIV Behavioral Surveillance of PWID aged 18 years or older, recruited using respondent-driven sampling and offered anonymous HIV testing after survey. We performed bivariate and multivariable analyses with log-linked Poisson regression of the generalized linear models to examine the associations between demographics and PWID service use, past-year HIV testing, and current antiretroviral therapy (ART) use. Among 10,311 HIV-negative PWID, 56% reported past-year HIV testing, and of the 553 HIV-positive PWID, 69% reported current ART use. Of the HIV-negative PWID, 64% (2874/4482) in drug treatment and 62% (3386/5440) who used syringe service programs (SSPs) reported past-year HIV testing. Among HIV-positive PWID, 75% (187/248) in drug treatment and 67% (200/298) SSP participants were on ART. In the adjusted multivariable model, past-year HIV testing was associated with drug use treatment (aPR 1.26, 95% CI 1.23–1.31) and SSP participation (aPR 1.19, 95% CI 1.13–1.26) among HIV-negative PWID. Current ART use was associated with drug use treatment (aPR 1.13, 95% CI 1.00-1.28) but the link was not significant probably due to small sample size. Findings support the expansion and improvement of PWID-targeted services, into comprehensive programs, including drug use treatment, SSP, and HIV testing and treatment.
AGENTES ANTINEOPLÁSICOS BIORREDUTÍVEIS: AVANÇOS E DESAFIOS APÓS 20 ANOS
Authors: Santana Pedro , Marques Gabriel , Cortezzi Mariana , Alves Ricardo , de Oliveira Renata
Published: October 2023

BIOREDUCTIVE ANTINEOPLASIC AGENTS: ADVANCES AND CHALLENGES AFTER 20 YEARS. Solid tumors are frequently affected by the presence of hypoxic cells, originating anomalous and disordered cell growth. This subpopulation presents resistance to conventional chemotherapy agents and radiotherapy, due to the difficulties of reaching the target region, the permanence in the G0 phase of cell cycle and the low local concentration of oxygen. The use of hypoxia activated prodrugs becomes, in this scenario, an effective and selective alternative in cancer therapy, though not yet available for clinical use in solid tumor treatment. Twenty years after the publication of the paper intitled “Agentes Antineoplásicos Biorredutíveis: Uma Nova Alternativa para o Tratamento de Tumores Sólidos” in the Química Nova journal (2002), the current essay aims to identify the advances in the pre-clinical and clinical studies regarding the development of new hypoxia-directed drugs and the improvement of the molecules previously studied. Moreover, to clarify the main challenges for the implementation and success of this drug class, in order to identify the hindrances for the preparation of a bioavailable, safe and selective drug.
MONITORAMENTO DE TRIHALOMETANOS (THMs) E DA QUALIDADE DA ÁGUA PARA ABASTECIMENTO PÚBLICO DA CIDADE DE CAVALCANTE, GOIÁS
Authors: Oliveira Dalila Kênia , Silva Larissa , de Brito Núbia Natália
Published: October 2023

MONITORING OF TRIHALOMETHANES (THMs) AND WATER QUALITY FOR PUBLIC SUPPLY IN THE CITY OF CAVALCANTE, GOIÁS. Trihalomethanes (THMs) are organohalogens compounds formed from the reaction between free residual chlorine and natural matter organic (humic substances) present in raw water from surface sources. This study aimed to evaluate the formation of THMs resulting from the application of chlorine for disinfection, in the water treating process for public supply in the city of Cavalcante, GO, located in the region of Chapada dos Veadeiros (Brazil). The results of physical-chemical analyses apparent color, turbidity, pH, free residual chlorine, consumed oxygen, hardness, total alkalinity and THMs demonstrated a positive and strong correlation between the formation of THMs and the hardness of treated water, as well as the chlorine consumed during disinfection process. It was observed an increase in apparent color, turbidity and consumed oxygen in the rainy season. These parameters indicate the presence of organic matter and that present a positive and moderate correlation with the formation of THMs.
Occurrence of Acanthamoeba spp. in a major river in the Philippines: Impact on water quality and health
Authors: Garrido Kaiser , Ileto Albert , De Jesus Verine , Emperador Wendyl , Francisco Andrea , Garcia Pauleen , Hadap Asha , Hernandez Mary Erika , Lacson Jose Francisco , Lagudas Czeska Rose , Padua Mark F. F. E. , Milanez Giovanni De Jesus
Published: October 2023

Rivers are important freshwater sources. They provide water for domestic and recreational use and serve as ecological sites for various microorganisms. Free-living amoebae are considered naturally occurring organisms in freshwater. However, their prevalence can suggest the water quality at a given source. Forty-five surface water samples from nine different sites were collected from the Marikina River. Samples were processed and cultured in non-nutrient agar (NNA) lawned with Escherichia coli, and were observed for 14 days using a light microscope. Thirty-six (80%) samples yielded a positive amoebic growth. Further molecular testing confirmed the presence of Acanthamoeba spp. using specific primer sets, JDP1 and JDP2. The current results of this study have shown a remarkable jump in the detection rate for free-living amoebae (FLAs). The continued deterioration of the Marikina River due to several human and non-human factors may have been the reason for this phenomenon. River clean-up, resettlement programs, and strict implementation of laws on waste disposal should be considered to rehabilitate the Marikina River.
The Medial and Final (CCC) Consonant Clusters in the Loanwords of Turkish: Is It an Illusion?
Authors: Baturay Meral Semra
Published: October 2023

Known as a language which strictly follows its phonotactic constraints showing low tolerance for the exceptions, Turkish employs a variety of phonological processes in the adaptation process of the foreign words into the language so as to make the phonologically improper loan words obey with the phonotactic and phonological constraints of the language. As one of these constraints, Turkish forbids the adjacency of three consonants (CCC) in the simplex forms given that CCC implies morphological complexity on the phonological string. However, there are still a number of foreign words with medial and final CCC clusters adapted to Turkish such as bandrol ‘banderol’, semptom ‘symptom’, portföy ‘portfolio’ and kuvartz ‘quartz’. Based on these observations, the aim of the present study is to investigate the appearance of CCC clusters in Turkish words, which are adapted to Turkish from foreign languages. In this regard, we claim that CCC in simplex words are only an illusion and there is no violation of phonotactic constraints. Accordingly, we argue that Turkish has three basic strategies in order to avoid CCC clusters while adapting the foreign words. As the first strategy, Turkish prefers the realization of a vowel following the initial CC as in /bandɯrol/ (i). The second strategy Turkish applies is to adapt the word which has a CCC cluster with only CC: e.g. /semtom/ and /kuvarz/ (ii). As the third option, certain adapted words with CCC clusters are stored in the mental lexicon as if they had a complex morphological structure port-föy (iii). We will give an account for these strategies in the light of government, licensing and constituent structure analyses.
Quinolines: A Promising Heterocyclic Scaffold for Cancer Therapeutics
Authors: Zhao Yinshen , Zhang Chaoyang , Liu Wan , Guo Zhiyuan , Zhang Yuqi , Wu Yuqi , Wei Chenyu , Wu Jianing , Yang Xianguang
Published: October 2023

The quinoline scaffold is a widely recognized heterocycle with applications
across various disease categories, ranging from malaria and viral infections to bacterial infections,
high cholesterol, and even tumors. Consequently, quinoline plays a crucial role
in the development of new drugs, and the field greatly benefits from advancements in
computer-aided drug design. This review aims to provide insights into the evolution of
quinoline and its derivatives, offering a comprehensive exploration of both marketed and
developing drugs. Furthermore, the function and mechanism of quinoline compounds are
introduced. Many studies rely on cell experiments to demonstrate drug cytotoxicity. In the
concluding section of this review, the interaction between quinoline compounds and targets
is simulated using computer-aided drug design methods. A thorough analysis is conducted
on the potential influencing factors affecting the binding state between quinoline
compounds and targets. Notably, the Pi-Alkyl interaction emerges as a significant contributor,
while hydrogen bonding is identified as a pivotal bond in these interactions. This
review serves as a valuable overview of the potential contributions of quinoline compounds
to cancer treatment. It seamlessly combines the essential functions of marketed
quinoline drugs with the promise held by emerging quinoline-based compounds. Additionally,
the simulation of interactions between quinoline compounds and proteins through
computer-aided design enhances our understanding of these compounds' efficacy.
Dess-Martin Periodinane (DMP) in Organic Synthesis-A Septennial Update (2015-till
Date)
Authors: Varala Ravi , Seema Vittal , Alam Mohammed Mujahid , Amanullah Mohammed , Dubasi Narsimhaswamy
Published: October 2023

Dess-Martin periodinane (DMP) is one of the hypervalent iodines that is most
frequently utilized as an oxidizing agent in organic chemistry. The authors of this septennial
review have critically and methodically presented representative applications of DMP in
organic synthesis from 2015 to the present, including oxidations, dehydrogenations, hetero
and homo-dimerizations, aromatizations, thiocyanations, halogenations, dearylations, ring
expansions, cyclizations, heterocyclic ring formation, and other miscellaneous reactions.
This review discusses the range and constraints of these transformations.
1,4-Dihydropyridine Derivatives: An Overview of Synthesis Conditions and
Biological Tests
Authors: de Fátima Silva Lago Aline , de Benedicto Danilo Forti Carvalho , da Silva Larissa , Thomasi Sérgio Scherrer
Published: October 2023

1,4-dihydropyridine is a versatile class of compounds with multiple biological activities, thus holding significant pharmacological potential. Recent studies have provided evidence concerning the anticancer,
antimicrobial, and anti-inflammatory properties of 1,4-dihydropyridines, as well as their potential in Alzheimer’s disease treatment. Therefore, this class of compounds is a promising candidate in studies of drug development and drug discovery. The major derivatives of 1,4-dihydropyridine can be synthesized through onepot synthesis in many different ways, varying the solvents, catalysts, and experimental conditions. Due to the
compound’s remarkable potential and ease of production, in this review we aimed to present the biological activities and synthesis methodologies of the main 1,4-dihydropyridine derivatives reported by scientific literature over the past decade.
Advancements in Synthesis and Application of 1,5-benzodiazepines a Privileged
Scaffold with a Wide Scope of Bioactivities
Authors: Dhabale Sonali A. , Kumar Sumit , Bhanwala Neeru , Khatik Gopal L.
Published: October 2023

A heterocyclic scaffold-like benzodiazepine (BZD) has shown a wide variety of
medicinal values and utmost importance in pharmaceutical industries. BZDs are sevenmembered
heterocyclic molecules and have many structural isomers, such as 1,2; 1,3; 1,4;
1,5; 2,4; and 2,3. Among these BZDs, 1,5-BZDs play a significant role in pharmacological
activities like anti-anxiety, anti-convulsion, antimicrobial, sedative, and hypnotics. These
moieties have been the subject of extensive research with the development of synthetic
methods, leading to the generation of numerous useful molecules over the last few decades.
Therefore, we have further explored the recent literature on the 1,5-BZDs synthesis and associated
biological activities to expand the role and utility of newer 1.5-BZDs. This review
article gives a recent and insightful thought about the synthetic methods and therapeutic
applications of 1,5-BZDs.
Coexistence of Cryptococcal Fungemia and Pneumocystis jirovecii Pneumonia in an HIV-Infected Patient: A Case Report
Authors: TATLI KIŞ Tuba , Yildirim Süleyman , Biçmen Can , Yücel Nur , Kirakli Cenk
Published: October 2023

Introduction:

Opportunistic infections caused by bacteria and fungi are common in human
immunodeficiency virus (HIV)-infected patients. Cryptococcus neoformans and Pneumocystis
jirovecii are the most common opportunistic infections in immunosuppressed individuals, but
their coexistence is rare. To our knowledge, this is the first case presented in Turkey involving the
coexistence of C.neoformans fungemia and P.jirovecii pneumonia.

Case Presentation:

A 26-year-old male patient presented with a cachectic appearance, cough, sputum,
weakness, shortness of breath, and a weight loss of 15 kg in the last three months. It was
learned that the patient was diagnosed with HIV three years ago, did not go to follow-ups, and did
not use the treatments. CD4 cell count was 7/mm3 (3.4%), CD8 cell count was 100 (54%) mm3,
and HIV viral load was 5670 copies/mL. In thorax computed tomography (CT), increases in opacity
in diffuse ground glass density in both lungs and fibroatelectasis in lower lobes were observed.
With the prediagnosis of P. jiroveci pneumonia, the HIV-infected patient was given trimethoprim--
sulfamethoxazole 15 mg/kg/day intravenously (i.v.). On the 4th day of the patient's hospitalization,
mutiplex PCR-based rapid syndromic Biofire (Film Array) blood culture identification 2 (BCID2)
test (Biomerieux, France) was applied for rapid identification from blood culture. C. neoformans
was detected in the blood culture panel. The treatment that the patient was taking with the diagnosis
of C. neoformans fungemia was started at a dose of liposomal amphotericin B 5 mg/kg/-
day + fluconazole 800 mg/day.

Conclusion:

While the incidence of opportunistic infections has decreased with antiretroviral therapy
(ART), it remains a problem in patients who are unaware of being infected with HIV or who
fail ART or refuse treatment. High fungal burden, advanced age, low CD4+ cell count, and being
underweight are risk factors for mortality in HIV-positive patients. Our case was a cachectic patient
with a CD4 count of 7 cells/mm3. Despite the early and effective treatment, the course was fatal.
Welcoming the “Metaverse” in Integrative and Complementary Medicine: Introductory Overview
Authors: Schoenberg Poppy L.A.
Published: October 2023

The digital transformation of healthcare is accelerating. At the forefront of this revolution is the development of the "metaverse." This multidimensional digital universe, where virtual and physical realities converge, is reshaping the potential of integrative and complementary medicine. In this special edition journal series, we explore how metaverse technologies such as virtual reality, augmented reality, avatars, digital twins, blockchain smart contracts, and more, are poised to revolutionize holistic healthcare. This article serves as a brief introduction to concepts, domains, and technologies of the metaverse, with scope for integrative and complementary medicine applications. It provides a groundwork and invitation for scholars to join this transformative frontier in healthcare, where the metaverse and integrative medicine unite to offer new dimensions for holistic well-being. Together, we explore the endless possibilities of "Welcoming the Metaverse in Integrative and Complementary Medicine," bridging the gap between the digital and the holistic for a more inclusive, diverse, and interconnected future of healthcare and wellbeing.
Identification of Emotional Spectrums of Patients Taking an Erectile Dysfunction Medication: Ontology-Based Emotion Analysis of Patient Medication Reviews on Social Media
Authors: Noh Youran , Kim Maryanne , Hong Song Hee
Published: October 2023

Background

Patient medication reviews on social networking sites provide valuable insights into the experiences and sentiments of individuals taking specific medications. Understanding the emotional spectrum expressed by patients can shed light on their overall satisfaction with medication treatment. This study aims to explore the emotions expressed by patients taking phosphodiesterase type 5 (PDE5) inhibitors and their impact on sentiment.

Objective

This study aimed to (1) identify the distribution of 6 Parrot emotions in patient medication reviews across different patient characteristics and PDE5 inhibitors, (2) determine the relative impact of each emotion on the overall sentiment derived from the language expressed in each patient medication review while controlling for different patient characteristics and PDE5 inhibitors, and (3) assess the predictive power of the overall sentiment in explaining patient satisfaction with medication treatment.

Methods

A data set of patient medication reviews for sildenafil, vardenafil, and tadalafil was collected from 3 popular social networking sites such as WebMD, Ask-a-Patient, and Drugs.com. The Parrot emotion model, which categorizes emotions into 6 primary classes (surprise, anger, love, joy, sadness, and fear), was used to analyze the emotional content of the reviews. Logistic regression and sentiment analysis techniques were used to examine the distribution of emotions across different patient characteristics and PDE5 inhibitors and to quantify their contribution to sentiment.

Results

The analysis included 3070 patient medication reviews. The most prevalent emotions expressed were joy and sadness, with joy being the most prevalent among positive emotions and sadness being the most prevalent among negative emotions. Emotion distributions varied across patient characteristics and PDE5 inhibitors. Regression analysis revealed that joy had the strongest positive impact on sentiment, while sadness had the most negative impact. The sentiment score derived from patient reviews significantly predicted patient satisfaction with medication treatment, explaining 19% of the variance (increase in R2) when controlling for patient characteristics and PDE5 inhibitors.

Conclusions

This study provides valuable insights into the emotional experiences of patients taking PDE5 inhibitors. The findings highlight the importance of emotions in shaping patient sentiment and satisfaction with medication treatment. Understanding these emotional dynamics can aid health care providers in better addressing patient needs and improving overall patient care.
Phytochemical Analysis of Lantana camera, Oxalis corniculata and Sphagneticola trilobata
Authors: D. Wadankar Gajanan , Wagh Ashwini
Published: October 2023

Lantana camera, Oxalis coniculata and Sphagneticola trilobata are rapidly growing weed in Maharashtra, were selected and aimed to investigate the presence of phytochemicals in leaf and stem. Aqueous, Acetone and Methanol Solvents were used for phytochemical analysis. Our findings provides evidence, that aqueous and organic solvent extracts of these plants contain medicinally important bioactive compounds.
La guerra entre Incas y Chancas. Relatos, sentidos e interpretaciones
Authors: Battcock Clementina
Published: October 2023

La guerra entre Incas y Chancas. Relatos, sentidos e interpretaciones es un libro que analiza las diferentes líneas argumentales que los cronistas andinos dieron a este pasaje fundacional incaico, mismo que dotó de un orden político y cultural al Tawantinsuyu, y que dista de considerarse exclusivamente dentro del plano mítico de la configuración social andina, pues los relatos de esta guerra contra chancas, sujetos a una cuidadosa crítica de fuentes, permiten dilucidar el sentido y las características de las instituciones del Cusco antes de la dramática ruptura de Cajamarca.
Vanguardia y americanismo Hidalgo, Borges, Huidobro
Authors: Rodríguez González Alberto
Published: October 2023

A principios del siglo XX, con la llegada de los aires renovadores de las vanguardias europeas, se reaviva en tierras americanas el antiguo debate sobre las posibilidades de un arte auténticamente americano. Los jóvenes poetas latinoamericanos ven en el llamado a la renovación estética la posibilidad de que la literatura americana logre al fin plena independencia de las letras europeas. Con el ánimo de mostrar al mundo la potencia de la joven lírica que la región produce, en 1926 aparece en Buenos Aires el Índice de la nueva poesía americana,obra que al reunir poemas de 62 poetas de nueve países marcará un hito como la primera antología de la poesía de vanguardia latinoamericana. Estudiar esta obra permite visualizar varios de los debates que el colectivo vanguardista emprende alrededor de la noción de americano y lo que significa en el contexto de la renovación poética.
América Latina y la latinidad.Génesis de la idea y el nombre de América Latina
Authors: Ardao Arturo
Published: October 2023

Este libro clásico de la Historiografía Latinoamericana nos ubica en un sendero firme para la comprensión del nacimiento y significado del nombre de América Latina. En virtud que ésta no alcanzará su verdadero significado si se prescinde de su doble dialéctica -de hechos y de ideas-, que lo hizo surgir como elemento integrante en la que fuera antitesis novedosa América Sajona-América Latina.Tal creación terminológica fue el desenlace obligado de circunstancias históricas muy complejas, entre las que la dominante resulta ser el avance del Norte sobre el Sur del hemisferio. Desde la anexión de Texas hasta las incursiones centroamericanas de Walker.
¿Hay lugar para la subjetividad en la escuela?
Authors: Follari Roberto
Published: October 2023

No se trata de pensar subjetivamente la subjetividad, sino de captarla en sus condiciones objetivas y causales. Ellas devienen de lo inconsciente y de las situaciones sociales. Lo primero remite a una tensión inevitable: la función de la educación es que las pulsiones puedan ser derivadas a lo socialmente aceptable, pero a la vez la subjetividad irrumpe sólo en la medida en que haya espacio para que se rompa la adaptación a la demanda social exterior. De modo que se trata de ofrecer en la escuela un espacio a la palabra subjetiva, por sobre la imposición cultural convencional. Para lo cual es necesario romper con las tendencias de la burocracia a borrar lo subjetivo, en cuanto ajeno a la homogeneidad cuantitativa.
Maximizing Profit for Cloud Brokers in The Era of Cloud Computing
Authors: Kaneti Venkata Ramana
Published: October 2023

Abstract: Cloud computing has experienced significant growth in recent years, with an increasing number of applications migrating to the cloud, where they can centrally manage a wide range of resources, including hardware and software. These resources are delivered over the internet as services, catering to customer demands. One of the key features of cloud computing is the pay-as-you-go model. However, due to the one-hour billing cycle and the discount structure favoring long-term users, many customers end up paying more than their actual usage. To address this issue, cloud brokers rent reserved Virtual Machines (VMs) from cloud providers at a reduced cost and offer them to users on an on-demand basis at a more affordable rate than what the cloud providers offer. Moreover, cloud brokers operate on a shorter billing cycle compared to cloud providers. This study focuses on configuring a cloud broker and determining the optimal pricing for its VMs to maximize its profits. Most cloud providers offer two primary payment options for their instances: On-Demand and Reserved Instances. With On-Demand instances, users pay for compute capacity per hour, making them suitable for short-term workloads. Reserved Instances provide significant discounts but require users to commit to long rental periods, disadvantaging short-term customers. The introduction of the cloud broker serves as a novel intermediary between cloud providers and cloud users, addressing the issues of both onehour billing cycles and the limitations on discounts for short-term users. This manuscript begins by introducing a multi-server queuing model, a revenue model, and a cost model, followed by a comprehensive analysis of the factors affecting them. It defines an optimization problem aiming to determine the optimal configuration for multi-server setups and VM pricing, all aimed at profit maximization. To address this optimization problem, a heuristic method is proposed, which combines partial derivatives and a bisection search. This method offers a practical approach to finding the optimal VM price and system scale, ultimately maximizing profit. This manuscript explores the critical role of cloud brokers in the cloud computing landscape and presents a comprehensive approach to optimizing their operations, ultimately benefitting both cloud providers and users.
A IMPORTÂNCIA DA ASSISTÊNCIA DE ENFERMAGEM NO PRÉ-NATAL DE BAIXO RISCO: um estudo de caso com os dados da Estratégia Saúde da Família I (ESF I) - Dona Andrezina - João Pinheiro - MG
Authors: Ribeiro Maria Eduarda Alves , Oliveira Sandy Sinfronio , Oliveira Ruan Romis de
Published: October 2023

The study carried out points to the need for quality nursing care during low-risk prenatal consultations in Primary Care, with the aim of promoting health, ensuring the necessary care for a healthy pregnancy, birth and postpartum period for the pregnant woman and the baby. Furthermore, a set of actions is observed that results in guaranteeing women's health, as pregnant women must know their rights and clarify their doubts about pregnancy, the right to a companion and the changes experienced during this period. It is remarkable that in addition to technical action, the nursing team is responsible for promoting a relationship of trust with the pregnant woman, in order to facilitate adherence to prenatal care in the first trimester of pregnancy, and quality monitoring in all consultations. A brief bibliographical review was carried out, using renowned research platforms. The objective was to search for data from pregnant women in the Family Health Strategy I Dona Andrezina, about the beginning of prenatal care and the age of pregnant women indirectly through tables provided by the nurse manager of the unit, preserving identity and personal data , the research result shows satisfactory data, since 91.67% of pregnant women inserted to prenatal care in the first trimester, as recommended and, in relation to age most of the percentage is in the usual risk parameters while 16.67% had late pregnancies.
INFLUÊNCIA DOS TRATAMENTOS DE SUPERFÍCIE EM IMPLANTES DENTÁRIOS NO PROCESSO DE OSSEOINTEGRAÇÃO: revisão narrativa de literatura
Authors: Oliveira Maria Eduarda Freitas , Pereira Túlio Silva
Published: October 2023

Dental implants are essential in modern dentistry, playing a crucial role in the predictability and success of oral rehabilitation procedures, restoring chewing function and aesthetics to the patient. Implant surface treatments offer greater opportunity to capture proteins, stabilize the blood clot and cells responsible for bone formation and remodeling, accelerating the biomechanical relationship of the implant-bone unit. A literature review was carried out using publications from various authors in the form of scientific articles and course conclusion works, which were available in vital databases: Google Scholar, Pubmed, Scientific Electronic Library Online (Scielo). The key words used for the search were: “Implantes dentários”, “Osseointegração”, “Reabilitação bucal” and “Propriedades de superfície”, the same terms being searched in English: “Dental implants”, “Osseointegration”, “Mouth rehabilitation”, “Surface properties”. The search period was from April to August 2023 and included articles in Portuguese and English. In this sense, the present study aimed to present a narrative review of the literature regarding surface modification techniques in surviving titanium implants and their relevance for osseointegration. It was possible to conclude that titanium implants with surface treatment have advantages when compared to the machined surface in influencing the bone integration procedure. Macro-, micro-, nano-textured and biomimetic surfaces can improve bone/implant connection, deposition of osteogenic molecules and initial firmness.
Fotogrametría SfM de bajo costo para monitorización de ensayos sobre estructuras laminares reticulares de madera deformadas elásticamente a escala real
Authors: Ortiz-Sanz Juan , Gil-Docampo Mariluz , Bastos Guillermo , Lara-Bocanegra Antonio José
Published: October 2023

Para validar modelos numéricos de resistencia de estructuras, es necesario medir su deformación bajo carga. La dificultad de dicha medición aumenta con su tamaño y su complejidad. En el presente estudio se determina la geometría de una estructura laminar reticular de gran tamaño tras una prueba de carga. La estructura fue cargada en sus cinco nodos centrales con un peso suspendido de 105 kg por nodo. Se generó el modelo 3D de la estructura sin carga y bajo carga, empleando fotogrametría usando software PhotoModeler Scanner y Metashape. El error máximo en la medida de las distancias sobre la escena fue 1,31 mm, que corresponde al 0,17 % respecto a la diagonal de la base de la estructura. El mayor error medio se dio bajo carga máxima, 0,70 mm de acuerdo a Metashapee y 0,44 mm en PhotoModeler Scanner. El perfil de la estructura bajo carga es coherente con la deformación prevista. La calidad de medida del modelo 3D resultó ser altamente uniforme. Este estudio releva el uso de fotos que han sido tomadas varios años después, a través de la fotogrametría utilizando softwares avanzados.
On tests of the quantum nature of gravitational interactions in presence of non-linear corrections to quantum mechanics
Authors: Spaventa Giovanni , Lami Ludovico , Plenio Martin B.
Published: October 2023

When two particles interact primarily through gravity and follow the laws of quantum mechanics, the generation of entanglement is considered a hallmark of the quantum nature of the gravitational interaction. However, we demonstrate that entanglement dynamics can also occur in the presence of a weak quantum interaction and non-linear corrections to local quantum mechanics, even if the gravitational interaction is classical or absent at short distances. This highlights the importance of going beyond entanglement detection to conclusively test the quantum character of gravity, and it requires a thorough examination of the strength of other quantum forces and potential non-linear corrections to quantum mechanics in the realm of large masses.
Turkic culture in museums of Russia and abroad: Introduction
Authors:   Marjani Institute of History of the Tatarstan Academy of Sciences, Tychinskikh Zaytuna A. ,   Tobolsk Complex Scientific Station of the Ural Branch of the Russian Academy of Sciences
Published: October 2023

The articles of researchers from Russia and abroad presented on a special topic of the issue of the journal are considered. The issue is dedicated to the richest cultural heritage of the Turkic peoples, stored in the collections of museums. The study and popularization of this heritage is an important and urgent task facing archaeologists, ethnographers, art historians and museologists. The material presented in the issue is a serious contribution of researchers to the further study of the history and culture of the Turkic peoples.
Tatar costume in museum collections of Russia
Authors:   Marjani Institute of History of the Tatarstan Academy of Sciences, Suslova Svetlana V.
Published: October 2023

The article is an overview of the collections on the folk costume of the Tatars, stored in the funds of numerous museums in Russia and Tatarstan. It contains information about the traditional types of upper and lower clothing, shoes and jewelry of the Volga-Ural Tatars (Kazan, Kasimov, Mishars, and Kryashens), as well as similar information on the costume of Astrakhan and Siberian Tatars living on the territory of the Russian Federation. Particular attention is paid to women's costume which characterizes folk arts and crafts to the greatest extent. A significant part of the collections is well passportised, indicating the region of existence, gender and age, and local terminology. The materials of the collections reflect the ethno-local and regional features of traditional clothing. On provision of firm attribution, museum objects have advantages over other historical sources. Artifacts from the early to mid–19th century and of the earlier period – medieval “imperishable” metal jewelry, leather goods, etc. are of particular value. They serve as a reliable illustration for the reconstruction of pre-national costume variations, which are extremely in demand in modern museum, theater, and ritual practices. When using the synchronous-diachronic methods of comparative historical analysis, museum artifacts considerably contribute to the study of the history of the Tatar costume, which largely reflects the ethno- and cultural genesis of the people as a whole.
The impact of corporate governance on default risk: BERTopic literature review
Authors: Colantoni Federico
Published: October 2023

This study utilizes the BERTopic methodology, a topic modelling tool that facilitates a meticulous exploration of existing literature, to comprehensively review the interplay between corporate governance and default risk. Through analysis of diverse empirical studies, it delves into understanding how corporate governance practices influence default probability. The study underscores the importance of effective governance mechanisms — board attributes, ownership structures, executive compensation, shareholder rights, and disclosure practices — in molding default probabilities. It also highlights the role of external governance mechanisms and regulatory frameworks in managing default risk. Notably, this research advocates for further investigation into emerging governance models and their integration with modern machine-learning techniques to amplify their impact.
A tale of two digital hospitals: A qualitative study of antimicrobial stewardship teams
Authors: Dort Bethany Van , Ritchie Angus , Penm Jonathan , Gray Timothy , Ronnachit Amrita , Baysari Melissa
Published: October 2023

Aim: To examine and understand the work processes of AMS teams across
two hospitals that use the same digital intervention, and to identify
the challenges and enablers to effective AMS in each setting. Methods:
Employing a contextual inquiry approach informed by the Systems
Engineering Initiative for Patient Safety (SEIPS) model, observations
and semi-structured interviews were conducted with AMS team members
(n=15) in two Australian hospitals. Qualitative data analysis was
conducted, mapping themes to the SEIPS framework. Results: Both
hospitals utilised similar systems, however, they displayed variations
in AMS processes, particularly in post-prescription review,
interdepartmental AMS meetings, and the utilisation of digital tools. An
antimicrobial dashboard was available at both hospitals but was utilised
more at the hospital where the AMS team members were involved in the
dashboard’s development, and there were user champions. At the hospital
where the dashboard was utilised less, participants were unaware of key
features, and interoperability issues were observed. Establishing strong
relationships between the AMS team and prescribers emerged as key to
effective AMS at both hospitals. However, organisational and cultural
differences were found, with one hospital reporting insufficient support
from executive leadership, increased prescriber autonomy, and resource
constraints. Conclusion: Organisational and cultural elements, such as
executive support, resource allocation, and interdepartmental
relationships, played a crucial role in achieving AMS goals. System
interoperability and user champions further promoted the adoption of
digital tools, potentially improving AMS outcomes through increased user
engagement and acceptance.
Integrating data from different taxonomic resolutions to better estimate community alpha diversity
Authors: Adjei Kwaku , Carvell Claire , Isaac Nick , Mancini Francesca , O'Hara Robert
Published: October 2023

Integrated distribution models (IDMs), in which datasets with different
properties are analysed together, are becoming widely used to model
species distributions and abundance in space and time. To date, the IDM
literature has focused on technical and statistical issues, such as the
precision of parameter estimates and mitigation of biases arising from
unstructured data sources. However, IDMs have an unrealised potential to
estimate ecological properties that could not be derived from the source
datasets if analysed separately. We present a model that estimates
community alpha diversity metrics by integrating one species-level
dataset of presence-absence records with a co-located dataset of
group-level counts (i.e. lacking information about species identity). We
illustrate the ability of IDMs to capture the true community alpha
diversity through simulation studies and apply the model to data from
the UK Pollinator Monitoring Scheme, to describe spatial variation in
the diversity of solitary bees, bumblebees and hoverflies. The
simulation and case studies showed that the proposed IDM produced more
precise estimates of the community diversity than the single models, and
the analysis of the real dataset further showed that the alpha diversity
estimates from the IDM were averages of the single models. Our findings
also revealed that IDMs had a higher prediction accuracy for all the
insect groups in most cases, with this performance linked to the
information provided by a data source into the IDM.
APPLICATIONS OF SCANNING ELECTRON MICROSCOPY ASSOCIATED WITH CRYOFRACTURE FOR ANALYSIS OF FISH OVARIES
Authors: Cassel Monica , Fortunato Celso E. S. , Galbiatti Gabriela D.
Published: October 2023

Scanning Electron Microscopy (SEM) allows a precise identification of
the surface of the structures. When associated with the cryofracture
technique, it allows a more detailed analysis, since the samples have
their internal structures exposed. Thus, the protocol and results of SEM
associated with cryofracture in Astyanax lacustris ovaries are
presented here in order to characterize the external and internal
structure of the oocytes. A. lacustris ovaries were collected,
prefixed in 4% paraformaldehyde, fixed in osmium tetroxide (2% OsO
) at 4 ºC and kept overnight in phosphate-buffered
saline. The samples were washed, immersed in DMSO at different
concentrations, followed by their fracture in 50% DMSO cooled by liquid
N and then immersed in 50% DMSO until returning to
room temperature. The fractured samples were taken for maceration in 1%
osmium, in a shaker for 15 hours. Afterwards, the samples were
post-fixed in 2% OsO for 2 hours at 4 ºC, dehydrated
in an increasing ethanol series and taken to the critical point
apparatus Balzers CPD-030 using liquid CO . This was
followed by the assembly of the blocks and the metallization of the
sample with gold ions, with the analyzes carried out in a Scanning
Electron Microscope Jeol JSM-7401F 5V. It was found that the
cryofracture technique provided images with greater internal detail of
the oocytes. Some specific characteristics of fish oogenesis could only
be observed using this new technique, with emphasis on the oocyte
envelope, the micropyle and the zona pellucida, as well as the
connective membrane associated with the ovarian structures.