bluuebunny/crossref_metadata_2025 huggingface dataset:
Toxicity Testing of Turi Putih Bark Extract on Mice Liver
Authors: Hasanah Mujemilatul , Rohmah Jamilatur
Published: January 2025

General background the use of natural extracts in assessing toxicity has gained attention due to the growing interest in alternative medicine and natural products. Specific background Sesbania grandiflora, commonly known as turi putih, is a plant with potential medicinal properties, but its safety profile regarding hepatic toxicity remains inadequately explored. Knowledge gap while previous studies have examined various plants for their pharmacological effects, research specifically focusing on the hepatotoxicity of turi putih extract is lacking. Aims this study aims to evaluate the toxicity of ethanol extract from the bark of Sesbania grandiflora on liver function, as measured by SGOT and SGPT levels, in Mus musculus. Results showed no mortality or toxic symptoms in the mice exposed to the extract. Macroscopic examination of the liver indicated normal color, consistency, and shape. Statistical analysis yielded p-values of 0.502 for liver weight, 0.226 for SGOT, and 0.366 for SGPT, indicating no significant effects from the treatment. Novelty this research contributes new insights into the safety profile of Sesbania grandiflora, demonstrating its non-toxic effects at the tested doses. Implications the findings suggest that the bark extract of turi putih may be safe for use, highlighting its potential in herbal medicine without adverse hepatic effects.
Highlights: 

No observed toxicity or mortality in mice after exposure to the extract.
Normal liver function indicated by SGOT and SGPT levels.
Potential safety of turi putih bark extract for medicinal use.

Keywords: Turi Putih, Hepatotoxicity, Sesbania grandiflora, Mice, Ethanol Extract
Important Probiotics to Management of Urinary Tract Infections in Women
Authors: Kadhum Ali Abd
Published: January 2025

General Background: Urinary tract infections (UTIs) are prevalent among women, often leading to repeated antibiotic treatment or surgical intervention, which increases healthcare costs. Specific Background: The rise of multidrug-resistant (MDR) bacteria complicates treatment strategies, necessitating alternative approaches to manage recurrent UTIs effectively. Knowledge Gap: Despite the documented benefits of probiotics in various health contexts, their role in preventing recurrent UTIs, particularly in regions like Nasiriyah City, remains inadequately explored. Aims: This study aimed to evaluate the efficacy of different probiotic strains (Lactobacillus rhamnosus, Lactobacillus reuteri, and Lactobacillus acidophilus) as adjuncts to conventional treatments in reducing UTI recurrence among women. Results: A total of 150 female participants were recruited, with 100 having a history of recurrent UTIs and 50 serving as a control group. The study revealed that Lactobacillus rhamnosus and Lactobacillus reuteri significantly reduced UTI recurrence rates compared to placebo, while Lactobacillus acidophilus demonstrated moderate efficacy. The analysis also indicated a high prevalence of antibiotic-resistant bacteria among UTI cases, highlighting the need for innovative treatment strategies. Novelty: This research uniquely contributes to the understanding of probiotic supplementation in UTI management, emphasizing the potential of Lactobacillus strains as effective preventative measures against recurrent infections. Implications: The study suggests incorporating probiotics, specifically Lactobacillus rhamnosus and Lactobacillus reuteri, into clinical practice to reduce antibiotic reliance and improve patient outcomes.
Highlights:

Probiotics reduce UTI recurrence rates effectively.
High antibiotic resistance highlights need for alternatives.
Consider probiotics as complementary therapy for better outcomes.

Keywords: urinary tract infections, probiotics, Lactobacillus, multidrug-resistant bacteria, prevention
Optimizing Profitability Through Resource Management in Kashkadarya's Hotel Industry
Authors: Kuldoshevich Berdiyev Jasur
Published: January 2025

Background: The hotel industry significantly influences regional economies, yet maximizing internal profitability remains challenging, especially for small businesses. Gap: Limited research addresses internal factors boosting profitability in regional hotel enterprises. Aim: This study examines how internal resources—like employee productivity and investment—impact profitability in Kashkadarya’s hotels. Results: Analysis shows profitability rates vary, with some hotels performing below the 8.77% average. Novelty: A predictive model reveals correlations between resources, labor efficiency, and profitability. Implications: Strategic resource optimization can enhance hotel industry profitability, offering insights for further research in similar sectors.
Highlights:

Internal resources, like employee productivity and investment, are key to boosting profitability.
Profitability varies significantly, with some hotels below the 8.77% average.
Strategic resource optimization can enhance overall industry profitability.

Keywords: Hotel Industry, Profitability, Internal Resources, Financial and Economic Indicators
Opportunities For Direct Foreign Investment in Small Industrial Zones in The Context of Economic Modernization
Authors: Ergashbekovich Halimzhanov Dilshod
Published: January 2025

At the present stage of the development of the world economy, the development of economic policy features that contribute to the socio-economic sustainable development of regions and their radical implementation into real life is becoming increasingly important every day. Increasing the possibilities of attracting foreign direct investment in the spheres and sectors of the economy, modernization of industrial enterprises, introduction of advanced foreign equipment and technologies into production is largely due to the creation of special economic zones, including small industrial ones. Based on this, the chosen research topic is becoming relevant today.
Highlights:
 

Strengthen economic zones for sustainable regional development and foreign investment.
Promote innovation, tech upgrades, and public-private partnerships in industrial zones.
Enhance investor protection, legal frameworks, and skilled workforce for economic growth.

 
Keywords: investments, investment policy, structural policy, industrialization, modernization, foreign investments, special economic zone, industrial zone, small industrial zone, youth industrial zone.
Studying Some Standards of Groundwater Quality and the Water Environment for Different Areas in Diyala Governorate
Authors: Yagoub Salih Saood
Published: January 2025

In the Diyla area, fourteen ground water samples were obtained for this study in high density polyethylene (HDPE) bottles that had been previously cleaned and filled with diluted HNO3. To prevent cross-contamination, the bottles were rinsed with the same water that would be used for the sample.  Using normal procedures, each sample was examined for five parameters: pH, EC, TH, Alkalinity, and F (APHA, 1995). A digital pH metre (Model 802 Systronics) was used in the field to measure pH, and a conductivity metre (Model 304 Systronics) was used to assess EC. The Trimble Juno 3D Handheld is used to help collect the geographic locations of the sample points (EC). Using regular EDTA, a titrimetric analysis of total hardness was conducted. Titrimetric analysis of alkalinity was performed with standard H2SO4.
Highlight:
 

Samples collected in HDPE bottles pre-rinsed with sample water.
pH, EC, TH, Alkalinity, F analyzed using APHA standards (1995).
pH, EC measured in field; hardness, alkalinity by titration.

 
Keywords: Word, Ground Water, Diyala City, Quality  Parameters, Ph Metre, Alkalinity
Burn Management by Nursing Students at Basrah University-Iraq
Authors: Jassim Firas A.
Published: January 2025

Background: In the process of managing burns, especially mass-burn injuries, first aid, and proper initial care are regarded as crucial measures. Improving the standard of burn treatment is largely dependent on the expertise and practical abilities of nursing students working in burn departments.Methodology: 150 students, both male and female, participated in a descriptive cross-sectional study design at Basrah University's College of Nursing to assess their burn management expertise. Data was gathered via a questionnaire with closed-ended questions. The survey is divided into two sections. The first section includes five questions on the students' sociodemographic traits, such as their age, gender, study type, graduation stage, and place of residence. Twenty questions in the second section of the survey ask about students' understanding of burn management. The study employed a standardized 3-point Likert scale with the options YES, NO, and I DON'T KNOW. 150 students were given the completed questionnaire form, which they read and completed. The researchers then collected the completed form. Results: Most of the sample were in the age interval 19-28,22% of the sample were males and 78% were females. The students had good knowledge about burn management. There are highly significant associations between the academic stage and the scores students got. Conclusions: Most of the samples were in the age interval 19-28 years. The students had good knowledge about burn management. There was a highly significant association between the academic stage and the scores the students got. Recommendations: Expand the burn course to enhance students’ knowledge and Introduce a simulation lab about burn management as part of the skill lab. In the College.
Highlights:
 

Knowledge of burn management linked to academic stage progress.
Most participants were female and aged 19-28 years.
Enhance skills with expanded courses.

 
Keywords: Burn management, nursing students, descriptive study, knowledge assessment, Basrah University
Histological and Physiological Study of Hyaluronic Acid Filler (Neuramis) in Laboratory Rats
Authors: Abdulameer Afrah Ali , Faris Satar Abood
Published: January 2025

Hyaluronic acid (HA) dermal fillers, derived from animal or non-animal sources, vary in physical and chemical properties, with numerous clinical trials assessing their effectiveness. This study examined the effects of Neuramis Volume Lidocaine on experimental animals over five durations (2, 4, 9, 10, and 13 weeks) via subcutaneous injections of 0.1 ml. Results showed a significant reduction in red blood cells, hemoglobin, and platelets after two weeks, which normalized by weeks 10 and 13. White blood cells and neutrophils significantly increased at two weeks but stabilized thereafter, while lymphocyte levels showed no significant long-term changes. Monocytes significantly decreased at two weeks but normalized by weeks 9-13. Scanning electron microscopy (SEM) revealed skin changes, including collagen bundle alterations and surface perforations. By week 10, the skin showed well-defined collagen structures and dense papillae, while earlier weeks exhibited more pronounced damage. These findings highlight HA fillers’ potential short-term physiological and histological impacts, which diminished over time.
Highlights:
 

Hyaluronic acid fillers vary in sources, properties, and clinical effectiveness.
Blood parameters altered early; histological changes observed, diminishing over time.
Fillers cause temporary physiological and histological issues, improving with duration.

 
Keywords: Hyaluronic acid, Histological study, Physiological study, Laboratory rats
The Impact of The Digital Economy on Achieving The Efficiency of The General Budget: A Study in Reforming The Iraqi Economy
Authors: Kadhim Roa'a Mohammed
Published: January 2025

The Iraqi economy operates with a large number of variables and seeks through them to achieve economic goals of economic growth, full employment, economic stability, reducing inflation and other goals, and this is done through macroeconomic policies, monetary and financial. The problem for the budget system is embodied in the urgent need for reform and development that includes the preparation and implementation of a model budget in a way that can enhance the ability and resilience of the financial and economic system to confront economic crises in a technologically advanced environment, where technological development is represented by the digital economy as a transformative force, embodying the convergence of technology and the Internet in shaping a new scene of economic activity, which includes a wide network of companies, institutions and individuals who use digital technologies and the Internet to create, exchange and consume goods, services and information. The digital economy is essentially based on data as the blood that feeds innovation and decision-making trends
Highlights:
 

Iraqi economy aims for growth via macroeconomic, monetary, and financial policies.
Budget reform crucial for resilience in a tech-driven, digital economy.
Data fuels innovation, shaping decision-making in economic activities.

 
Keywords: Digital economy, General Budget, Efficiency, Iraqi Economy
A Theoretical Study of Phytochemicals as Green Corrosion Inhibitors
Authors: Radhi Mustafa Jassim , Mizeel Israa Mohsen
Published: January 2025

In this research, the effectiveness role of phytochemicals as agents for inhibiting corrosion was studied, including eugenol, cinnamaldehyde, and cinnamic acid. All quantum chemical calculations related to the phytochemical molecules studied using Biovia software and DFT technique are presented. A comparison of the adsorption properties on the iron(110) surface and corrosion inhibition of the studied phytochemicals is discussed .Furthermore, computational methods involving Monte Carlo simulations and molecular dynamics were employed to evaluate adsorption energies and  stable configurations of inhibitors at the iron (110) surface. The phytochemicals under investigation have the following adsorption energies: Eugenol Eads = -98.442869 kcal/mol > Cinnamic acid Eads = -93.00807248 kcal/mol > Cinnamon Eads = -87.671968 kcal/mol. All theoretical studies confirmed that the surface adsorption effectiveness and corrosion inhibition performance of the studied phytochemicals follow the sequence; Eugenol (HH3) > cinnamic acid (HH2) > cinnamaldehyde (HH1).
Highlights:
 

hytochemicals (eugenol, cinnamaldehyde, cinnamic acid) studied for corrosion inhibition.
Quantum chemical calculations and DFT technique used for adsorption properties.
Adsorption energy sequence: Eugenol > Cinnamic acid > Cinnamaldehyde.

 
Keywords: phytochemicals , DFT , corrosion inhibitors
Research Trends and Dominant Theories in Sebelas Maret Business Review
Authors: Penatari Resi Intan , Sutopo Bambang
Published: January 2025

Background: Bibliometric analysis is vital for understanding research trends and scholarly impact. Sebelas Maret Business Review (SMBR), active since 2016, has published 99 articles, yet its academic contribution remains underexplored. Gap: Limited studies address SMBR’s research focus, theoretical frameworks, and practical implications. Aim: This study analyzes SMBR publications (2016–2023) to identify trends, dominant theories, and key variables. Results: Findings highlight Agency Theory and Signaling Theory as prevalent frameworks, with "work environment" (9 cases) as a key independent variable and "performance" (12 cases) as the dominant dependent variable. Trends show a focus on digital transformation and COVID-19 impacts. Novelty: Using VOSviewer, this study offers the first bibliometric mapping of SMBR, revealing thematic and collaborative networks. Implications: The analysis informs future research, emphasizing sustainability and AI in management, while aiding practitioners and policymakers in evidence-based decision-making.
Highlights:

Research Focus: SMBR primarily explores managerial behavior, transparency, and performance using dominant theories like Agency and Signaling.
Key Variables: "Work environment" and "performance" are the most frequently analyzed variables, reflecting organizational efficiency priorities.
Novel Contribution: First bibliometric mapping of SMBR using VOSviewer, revealing research trends and collaboration networks.

Keywords: Bibliometric Analysis, Research Trends, SMBR
The Current Situation of Using Internet Services in The Modern Organization of Training Sessions
Authors: Abdusalyamovich Djurayev Botir
Published: January 2025

The modern use of Internet services in the organization of educational activities is a dynamically developing direction that radically changes traditional approaches to education. In the context of the rapid development of information technology, educational institutions are forced to adapt to the new reality by introducing innovative tools and platforms that provide access to educational resources, simplify the interaction between teachers and students, and also expand the possibilities of independently mastering the material.
Highlights:

Modern internet transforms traditional education approaches dynamically.
Educational institutions adapt with innovative tools and platforms.
Expands access, simplifies interaction, enhances independent learning opportunities.

Keywords: Internet services, rapid development, information technology, between teachers and students
Review Article: Role of FeoA in the Interaction with the Fe2+-Fur Complex in E. coli
Authors: Alali Sheama
Published: January 2025

Iron is an essential micronutrient for bacteria, functioning as a cofactor in vital processes such as electron transport, heme synthesis, and DNA replication. However, excess iron triggers the Fenton reaction, producing harmful reactive oxygen species. To manage this, E. coli has evolved regulatory systems to maintain iron balance despite its scarcity in the environment, with free iron concentrations as low as 10^-18 M. The iron-binding repressor protein Fur regulates genes involved in iron uptake, transfer, and storage. The FeoABC system is the primary route for Fe2+ entry, with FeoB enabling the reduction of Fe3+ to Fe2+ and transferring it to FeoA, which likely prevents wasteful iron binding to negatively charged cellular membranes. This efficient management of iron acquisition and storage not only ensures cellular survival but also provides insights into bacterial metabolic strategies for optimizing iron use while minimizing damage from reactive oxygen species.
Highlights:

Iron is crucial for bacterial functions like DNA replication and heme synthesis.
Excess iron triggers Fenton reaction, creating harmful reactive oxygen species.
FeoABC system regulates Fe2+ uptake and balances iron acquisition in bacteria.

Keywords: Iron homeostasis, FeoABC system, E. coli, Fur protein, reactive oxygen species
Ecotourism Cluster and Prospects for The Sangzor-Jizzakh Reservoir
Authors: Shukurboeva Sanaeva Lola , Safarovich Safarov Karimjon
Published: January 2025

One of the ecotourism clusters in the Jizzakh region is the Sangzar-Molguzar ecotourism cluster, the creation of which is the basis for the systematic and sustainable development of ecotourism in the region, as well as the formation of local infrastructure.
Highlights:

Sangzar-Molguzar Cluster: Foundation for Jizzakh's ecotourism development.
Ecotourism Goal: Systematic, sustainable growth in regional tourism initiatives.
Local Infrastructure: Cluster drives infrastructure formation in the area.

Keywords: Ecotourism, cluster, ecology, Koytash, stones of various shapes, eco-routes, investments, benefits, ecotourism areas, Forish district.
Efecto antibacteriano de tres cementos de obturación en endodoncia frente al Enterococcus faecalis y Cándida albicans, estudio in vitro
Authors:   , Navarrete Vasquez Sandra Gabriela
Published: January 2025

Objetivo: Comparar el efecto antibacteriano de tres cementos selladores en cepas de Enterococcus faecalis, y Cándida Albicans. Estudio in vitro. Materiales y métodos: El diseño de la investigación fue experimental, se utilizó el método de difusión en agar Müeller Hinton, dentro de pocillos de 5 x 5 mm. en placas Petri con el agar correspondiente para cada cepa anteriormente activada e inoculada, en donde se colocaron los diversos cementos, midiendo los halos de inhibición existentes previa incubación en estufa a 37ºC por 24 y 48 horas. La medida del halo de inhibición de cada placa fue realizada con un calibrador digital pie de rey (vernier digital) y fue registrado en la ficha de recolección de datos. Resultados: El cemento hidráulico Totalfill BC Sealer tuvo un mayor halo de inhibición en las cepas de enterococcus faecalis y el cemento Grossdent, (óxido de zinc y eugenol) tuvo un mayor halo de inhibición en las cepas de cándida albicans. El cemento Sealer 26 (resina epoxy e hidróxido de calcio) fue el que obtuvo el menor halo de inhibición en ambas pruebas. Conclusiones: el cemento hidráulico Totalfill BC Sealer si produce efecto antibacteriano y antifúngico en cepas de enterococcus faecalis y cándida albicans en los periodos de 24 y 48 horas.
Factores que influyen en el peso de vellón y categoría de la fibra en una población de alpacas de Arequipa
Authors:   , Serna Castañeda Alisson Valeria , Goycochea Porras Gianella Edith
Published: January 2025

Objetivo. Determinar las características productivas del Centro de Desarrollo Alpaquero de Toccra (CEDAT) y los factores que influyen en la calidad de la fibra de alpaca basada en el peso de vellón y categoría de la fibra. Materiales y métodos. Se evaluaron los registros de las alpacas del Centro de Desarrollo Alpaquero en Toccra, Callalli, Arequipa durante el periodo del 2004 al 2019, estudiando 794 alpacas de la variedad Huacaya y 93 Suri. Resultados. El peso de vellón promedio fue de 3.07 ± 0.98 kg con categoría de fibra de 20.76% de animales extra finos y 64.36% fina. Los factores que influyen en el peso de vellón son el número de esquila, sexo y tipo de vellón, mientras que para la categoría de la fibra son número de esquila, sexo y color. Conclusiones. Los factores relacionados se deben tener en cuenta para evaluar correctamente la productividad de una población alpaquera en nuestro país y así poder generar mejoras genéticas, ambientales y de manejo de estos puntos específicos. Por otro lado, el peso de vellón de los años 2004 al 2019 ha disminuido ya que el centro se enfocó en obtener una fibra más fina, lo que conlleva a la disminución del peso de vellón promedio.
Factores asociados a la duración de la lactancia materna en niños menores de 2 años en el Perú 2021-2022
Authors:   , Zorrilla Cabrejo Mirella Georgina
Published: January 2025

Introducción: La duración de la lactancia materna es crucial para la salud infantil, sin embargo, la prevalencia ha disminuido en los últimos años, por lo tanto, el objetivo de este estudio fue determinar los factores asociados a la duración de la lactancia materna en niños menores de 2 años en el Perú 2021-2022. Metodología: Estudio analítico transversal, a través del análisis secundario de datos de la Encuesta Demográfica y de Salud Familiar (ENDES) del año 2021 y 2022. El tamaño muestral fue de 4951 niños/niñas con sus respectivas madres. Se evaluaron factores infantiles y maternos utilizando el Estadístico F corregida, además, se calculó la razón de prevalencia cruda (RPc) y la razón de prevalencia ajustada (RPa) mediante la Regresión de Poisson con varianza robusta. Resultados: La prevalencia de la duración de lactancia materna hasta los 6 meses es de 85,3% y solo el 14,7% tiene una duración hasta los dos años. El no contacto piel a piel precoz bebé-madre está asociada con una duración hasta los 6 meses de lactancia materna (p <0,01) (RPa 1,19), el consumo de bebidas diferentes a la leche materna los primeros 3 días de nacido influye en una duración de lactancia materna de 0-6 meses (p <0,01) (RPa 0,66),el 30,7% de las madres adolescentes logran una duración de lactancia materna de 6 meses (p<0,01) (RPa 2,49),por el contrario, el lugar de residencia rural ,el grado no superior y un menor ingreso económico se asocian a una lactancia mayor a 6 meses. Conclusiones: Los resultados asocian no recibir contacto piel a piel precoz bebe-madre, edad materna menor de 18 años, grado superior, residir en zona urbana y mayor ingreso económico con una menor duración de lactancia materna en niños menores de 2 años.
WITHDRAWN: Exploring the Molecular Mechanism of Estrogen Therapy Effectiveness after TCRA in IUA Patients at single-cell level
Authors: Du Yue , Shuai Ruzhen , Luo Sang , Jin Yiran , Xu Fengjuan , Zhang Jingyi , Liu Dan , Feng Limin
Published: January 2025

The full text of this preprint has been withdrawn by the authors due to author disagreement with the posting of the preprint. Therefore, the authors do not wish this work to be cited as a reference. Questions should be directed to the corresponding author.
Synthetic ratio computation for programming population composition and multicellular morphology
Authors: Zhong Chao , Church George , An Bolin , Tang Tzu-Chieh , Lu Timothy , Wang Teng , Zhang Qian , Gan Kesheng , Liu Kun , Liu Yuzhu , Wang Yanyi , Shaw William , Liang Qianyi , Wang Yaomin
Published: January 2025

Recent advancements in genetic engineering have provided diverse tools for artificially synthesizing population diversity in both prokaryotic and eukaryotic systems. However, achieving precise control over the ratios of multiple cell types within a population derived from a single founder remains a significant challenge. In this study, we introduce a suite of recombinase-mediated genetic devices designed to achieve accurate population ratio control, enabling the distribution of distinct functionalities across multiple cell types. We systematically evaluated key parameters influencing recombination efficiency and developed data-driven models to reliably predict binary differentiation outcomes. Using these devices, we implemented parallel and series circuit topologies to create user-defined, complex cell fate branching programs. These branching devices facilitated the autonomous differentiation of precision fermentation consortia from a single founder strain, optimizing cell-type ratios for applications such as pigmentation and cellulose degradation. Beyond biomanufacturing, we engineered multicellular aggregates with genetically encoded morphologies by coordinating self-organization through cell adhesion molecules (CAMs). Our work provides a comprehensive characterization of recombinase-based cell fate branching mechanisms and introduces a novel approach for the bottom-up, high-resolution construction of synthetic consortia and multicellular assemblies.
Performance and Safety of PowerGlide Pro® Extended Dwell Peripheral Catheters in an Emergency Medicine Unit: A Prospective Observational Study
Authors: Mussa¹ Baudolino , Mosca¹ Christian , Restivo¹ Angela , Robasto¹ Giulia , Pivetta¹ Emanuele , Lupia Enrico
Published: January 2025

Background: The increasing complexity of hospital care has led to a growing demand for versatile vascular access devices. Extended dwell peripheral (EDP) catheters, such as the PowerGlide Pro®, have emerged as potential alternatives to both short-term peripheral and long-term central venous catheters.
Objective: To evaluate the performance, safety, and efficacy of the PowerGlide Pro® EDP catheter in a sub-intensive care unit setting, comparing its outcomes to historical data on other vascular access devices.
Methods: A prospective observational study was conducted on 300 patients requiring intravenous therapy for ≥7 days in the Emergency Medicine Unit at A.O.U. Città della Salute e della Scienza di Torino, Italy, from December 2019 to October 2020. Primary outcomes included complication rates, reasons for removal, and duration of catheter use.
Results: Of 283 successfully placed devices, 23 complications (8.1%) were observed, with only 12 (4.2%) resulting in device removal. The average duration of catheter use was 7.26 ± 5.51 days (range: 1-31 days). Ultrasound-guided insertion was successful in 94.7% of cases.
Conclusion: The PowerGlide Pro® demonstrated superior performance with a low rate of complications requiring removal compared to traditional peripheral catheters and comparable performance to midline and PICC devices. These findings suggest its potential as an effective alternative for medium-term vascular access in sub-intensive care settings.
Contextual factors’ Correlates on Teachers’ ICT Beliefs and their ICT use in urban slum public basic schools in Ghana
Authors: Baako Issah , Abroampa Winston Kwame , Osei Eric Opoku
Published: January 2025

This study examined the implementation of Information and Communications Technology for Education (ICT4E) in public basic schools situated in urban slums in Ghana. The research focused on contextual factors, teachers' ICT beliefs, and the extent of ICT usage in these educational settings. The primary objective is to investigate the relationships between contextual factors, teachers' beliefs about ICT, and their actual use of ICT in the classroom. Data were collected from 179 randomly selected teachers through a structured questionnaire using a cross-sectional survey design. The collected data were then analyzed using IBM SPSS v.26 and Pearson's correlation coefficient to examine the associations between the variables. The results reveal a weak but statistically significant relationship between contextual factors and teachers' ICT usage, suggesting that the environmental context plays a role in ICT adoption, albeit with limited influence. The study also finds a weak and statistically insignificant relationship between contextual factors and teachers' ICT beliefs, indicating that external conditions may not heavily impact teachers' attitudes toward ICT. Furthermore, the study identifies a very weak but statistically significant relationship between teachers' ICT beliefs and their ICT usage, implying that teachers' beliefs do have a minimal role in how they integrate technology into their teaching. The findings underscore the significance of considering contextual factors when implementing ICT in schools, particularly in resource-constrained environments such as urban slums. The study advocates for comprehensive and targeted interventions that address both the contextual challenges and the need to foster positive ICT beliefs among teachers. These interventions are crucial for establishing equitable and high-quality technology-enhanced learning environments that can yield long-term educational benefits.
Novel Ectodysplasin-A Variants: Structural and Functional Basis of Hypohidrotic Ectodermal Dysplasia
Authors: Ranjan Prashant , Devi Chandra , Bansal Rajesh , Srivast Vandita , Srivast Vinay Kumar , Das Parimal
Published: January 2025

This study investigates two novel variants in the EDA, c.680G > A (p.G227E) and c.649_666del (Δ215–220), identified in X-linked ectodermal dysplasia and syndromic tooth agenesis cases. These variants were identified through Sanger sequencing and mapped to highly conserved regions of EDA. Bioinformatics tools consistently classified them as deleterious, with significant disruptions predicted in protein stability, hydrophobicity, and secondary structure. Structural analysis revealed that p.G227E caused a glycine-to-glutamic acid substitution, altering hydrophobicity and secondary structure, while Δ215–220 disrupted a conserved hydrophobic region, leading to increased protein instability Functional studies revealed reduced expression of EDA and WNT4 proteins, alongside increased IκB levels and decreased NF-κB mRNA expression, indicating impaired EDA-NF-κB signaling. Subcellular localization analyses demonstrated diminished cytoplasmic expression of the EDA Variants proteins, corroborated by in silico predictions. Post-translational modifications (PTMs) and gene ontology (GO) analyses revealed alterations in processes critical for ectodermal development, including macromolecule biosynthesis, nitrogen metabolism, and receptor signaling. Molecular dynamics simulations highlighted increased rigidity, compact structure, and reduced flexibility in the EDA variants proteins compared to EDA Wild Type (WT). Interestingly, neither variant significantly impacted calcium or mitochondrial potential under normal experimental conditions, suggesting their pathogenic effects arise primarily from disrupted protein interactions and signaling pathways. This study integrates molecular, bioinformatics, and functional analyses to elucidate the pathogenicity of these novel EDA variants, providing insights into ectodermal dysplasia mechanisms and paving the way for future therapeutic strategies targeting these EDA variants.
What Drives House Prices? A Linear Regression Approach to Size, Condition, and Features
Authors: Ju Xiaolin , Chakma Vaskar , Amin Misbahul , Chakma Joy Arkhid
Published: January 2025

This research examines the key factors that influence house prices, focusing on how size, condition, and structural features contribute to property valuation. A multivariate analysis using a Linear Regression model was conducted to assess the relationships between crucial features such as square footage, number of bedrooms, bathrooms, floors, and property condition. The analysis revealed that square footage and bathrooms exhibit the strongest positive correlations with house prices (both with correlation values of 0.76), indicating their significant impact on property valuation. In contrast, factors like condition and view demonstrated weaker correlations, suggesting a more limited influence. The Linear Regression model achieved an R-squared value of 0.75, explaining 75% of the variation in house prices based on these features. While the model effectively highlights key price determinants, its limitations in handling non-linear relationships and sensitivity to outliers are noted. This study emphasizes the importance of a nuanced, data-driven approach in understanding house price dynamics, offering valuable insights for buyers, sellers, and industry professionals. Future work could explore advanced predictive models and incorporate additional features to enhance forecasting accuracy.
Mutfak Farkındalığı ve Özgünlüğü: Adana Mutfağına Yönelik Bir Araştırma (Culinary Awareness and Authenticity: A Study on Adana Cuisine)
Authors: İNCE Cemal , GENÇAY İbrahim Cemal , ÇAKAZ Şeyma
Published: January 2025

Adana yöresel gastronomik kimliği, yöreye özgü zengin çeşitlilikteki seçenekleri ile gastronomi turizmi ve turizm pazarlaması konularında önemli avantajlara sahiptir. Son yıllardaki gastronomi ve gastronomi turizmindeki olumlu gelişmeler de Adana mutfağına olumlu katkılar sunmaktadır. Yerel halk ve yerel mutfağın paydaşları kendi mutfak kültürleri hakkında yeterli farkındalığa sahip değil ise bu ürünleri yeterli düzeyde müşterilerine anlatamazlar ve pazarlayamazlar. Bu nedenle bu araştırmada; Adana yerel halkının Adana mutfağının özgünlüğü hakkındaki görüşleri, özgün ve geleneksel yiyecekleri pişirme sıklıkları, coğrafi işaretli ürünler ve yöresel mutfak farkındalıklarının belirlenmesi amaçlanmıştır. Çalışma sonucuna göre Adana mutfağının imaj farkındalığı genel olarak olumludur. İmaj farkındalığı en yüksek olan “Adana yemekleri çekicidir “ önermesi olurken “Adana yemekleri bilimsel teknikler ile pişirilir” önermesi en düşük imaj farkındalığına sahiptir. Çalışmada 27 yemek Adana’ya özgün olarak belirlenirken, 11 yemek Adana’ya özgün olarak kabul edilmemiştir. 13 yemek konusunda ise belirsizlik ortaya konmuştur. Yiyeceklerin pişirilme sıklığı ile cinsiyet ilişkisinde kadınlar 10 yemeğin, erkekler ise 1 yemeğin hiç pişirilmediğini belirtmektedirler. 39 yemekte ise cinsiyetler arasında bir farklılık belirlenememiştir.
Ev Hanımlarının Yeme Pratikleri Üzerine Bir Değerlendirme (An Evaluation on The Eating Practices of Housewives)
Authors: KAMAN Gizem Sultan
Published: January 2025

Kadınlar ev içerisinde ürettikleri yiyecekler ile hem kültürel yeme pratiklerini muhafaza eden hem de yeniden şekillendiren bireylerdir. Bu araştırmanın amacı, ev hanımlarının yeme pratiklerinin şekillenmesinde cinsiyetin, diğer sosyoekonomik faktörlerden nasıl farklılaştığının incelenmesidir. Çalışma kapsamında nitel araştırma yöntemlerinden yararlanılmıştır ve etnografik desen benimsenmiştir. Veriler, nitel araştırma yöntemlerinden olan görüşme tekniği kullanılarak toplanmıştır. Toplamda 13 kişi ile görüşüldükten sonra verilerin doygunluğa ulaştığı görülmüş ve veri toplama süreci durdurulmuştur. Elde edilen verilerin analizinde ise içerik analizi kullanılmıştır. Araştırmadan elde edilen bulgular doğrultusunda ev hanımlarının yeme pratikleri; yeniliği reddedenler, kilo kontrolcüler, hedonistler ve modernistler olarak dört grup altında toplanmıştır. Yeniliği reddedenler grubunda hane içerisinde yemeğe ilişkin bütün görevler kadınlara atfedilirken, kilo kontrolcüler grubunda yemek hazırlama sürecinin kadın-erkeğin ortak görev alanı olarak benimsendiği sonuçlarına ulaşılmıştır. Modernistler grubu gelenekselciliği reddederek ticarileşmiş yeme pratiklerini kabul etmekteyken hedonistler grubu, sebze-et tüketimini sınırlandırmamakta, haftada 1-3 gün dışarıdan yemek siparişi vermektedir. Gelecekte yapılacak olan araştırmalarda erkek katılımcılar da araştırma kapsama dahil ederek karşılaştırmalı sonuçların üretilmesi mümkün olacaktır.
Kırım Tatar Mutfak Kültüründe Unutulmaya Yüz Tutan Özel Gün Yemekleri ve Gelenekler (Special Occasion Dishes and Traditions That Are About to Be Forgotten in Crimean Tatar Culinary Culture)
Authors: YURTSEVEN Gülsüm , ÖZBAY Gülçin
Published: January 2025

Kırım Tatar Mutfak Kültüründe Unutulmaya Yüz Tutan Özel Gün Yemekleri ve Gelenekler başlıklı araştırma makalesi, Yalova Subaşı’nda yaşayan Kırım Tatarlarının yemekleri, yemek tarifleri, özel ve dini gün yemekleri ve bu yemekler etrafında oluşan gelenekleri araştırmayı amaçlamaktadır. Bu amaç doğrultusunda Yalova Subaşı’ nda yaşan Kırım Tatarları arasından amaçlı örneklem seçme tekniğiyle 10 kişi seçilmiş. Ve bu kişilerle yarı yapılandırılmış görüşme gerçekleştirilmiştir. Bu görüşmeler neticesinde Çalışmadan elde edilen verilerle içerik analizi yapılmıştır. Bu araştırmada, Yalova’ya yerleşen Kırım Tatarlarının Hıdırellez, iftar, sahur, arife, bayram ve düğün yemekleri ile bu yemekler etrafında şekillenen geleneklerini tespit etmek ve unutulmalarını önlemek amacıyla bu gelenekleri kayıt altına almak hedeflenmektedir. Yapılan görüşmeler sonucu; Yalova Kırım Tatar kültürüne ait Hıdırellez ekmeği kalakay ve kalakay tıgırtma geleneği, sahur, iftar, bayram gibi dini günlere özgü yemekler, unutulmaya yüz tutmuş tarifler, bazı yemek görselleri ile düğün yemekleri ve geleneklerine ilişkin veriler elde edilerek kayıt altına alınmıştır.
Rize deki Konaklama Tesislerine Yapılan Çevrimiçi Yorumların İncelenmesi (Review of Online Comments on Accommodation Facilities in Rize)
Authors: AYDIN Melis , AKTUNA Can
Published: January 2025

Bu çalışmanın amacı Rize ilinde bulunan turizm işletme belgeli konaklama tesislerine yapılan misafir yorumlarının incelenmesi ve inceleme sonrasında elde edilen verilere göre bu işletmelerin olumlu ve olumsuz yönlerinin ortaya çıkarılmasıdır. Elde edilen veriler ışığında konaklama tesislerinin güçlü ve zayıf yönlerinin ortaya çıkarılması ve bölgenin diğer destinasyonlarla rekabetinde güçlendirilmesi adına önerilerde bulunulmuştur. Veriler TripAdvisor web sitesinden alınmış ve MAXQDA programında analiz edilmiştir. Analiz sonucunda Rize’de bulunan turizm işletme belgeli konaklama tesislerine yapılan olumlu misafir yorumlarında odalar, kahvaltı ve temizlik gibi konular ön plandayken olumsuz yorumlarda da odalar, temizlik ve personel gibi başlıklar göze çarpmıştır. Son olarak bu yorumlarla ilgili konaklama tesislerine yönelik önerilerde bulunulmuştur. Bunlara ek olarak Rize ili için daha önce benzer bir çalışmanın yapılmamış olması da çalışmayı önemli kılmaktadır.
İklim Değişikliğinin Ekoturizm Üzerindeki Etkileri ve Kentsel Alanlarda Adaptasyon Yaklaşımları: Türkiye ve Çeşitli Dünya Kentleri Üzerinden Bir Değerlendirme (Climate Change Impacts on Ecotourism and Adaptation Approaches in Urban Areas: An Assessment on Türkiye and Various World Cities)
Authors: TURAN A.Menaf , GÖKSOY SEVİNÇLİ Berfin , SARAÇOĞLU Hande
Published: January 2025

İklim değişikliği, doğal kaynaklara dayalı turizm türü olan ekoturizmi doğrudan ve dolaylı olarak etkilemektedir. Çalışmada, “İklim değişikliğinin ekoturizm üzerindeki etkilerine karşı hangi kentsel adaptasyon yaklaşımları uygulanmaktadır?” sorusuna yanıt aranmıştır. Çalışmanın amacı, iklim değişikliği nedeniyle artan sıcaklıklar, sel, orman yangınları ve ekosistem bozulmalarının ekoturizm destinasyonlarındaki olumsuz etkilerini belirlemek ve bu sorunlara yönelik kentsel adaptasyon yaklaşımlarını ortaya koymaktır. Araştırmada, literatür taraması yöntemi kullanılmıştır. Yöntem, mevcut bilimsel çalışmaların derinlemesine analiz edilmesini sağlayarak iklim değişikliğinden olumsuz olarak etkilenen ekoturizm ve kentsel adaptasyon yaklaşımlarının bütüncül bir perspektifle ele alınmasını sağlamıştır. Çalışmanın önemi, iklim değişikliği karşısında dirençli hale getirilmesi gereken ekoturizmin, kentsel adaptasyon projeleriyle nasıl desteklendiğinin dünya örnekleri ve Türkiye üzerinden ele alınmasıdır. Araştırmanın bulguları, Paris’teki yeşil alan uygulamaları, Toronto’daki Yeşil Turizm Haritası, İzmir’deki Bademler Doğal Yaşam Köyü gibi kentsel adaptasyon projelerinin ekoturizmi desteklediğini göstermektedir. Bu projeler, doğal kaynakların korunmasını, çevresel etkilerin azaltılmasını ve yerel toplulukların ekonomik katkısını hedeflemektedir. Sonuç olarak, kentsel adaptasyon stratejileri, iklim değişikliğinin ekoturizm üzerindeki olumsuz etkilerini hafifletmede önemli bir araç olarak değerlendirilmektedir.
Öz Güvenin Toplumsal Cinsiyet Rol Stresi ve Turizmde Kariyer Yapma İsteğine Etkisi: Turizm Bölümlerinde Okuyan Öğrenciler Üzerine Bir Araştırma (The Effect of Self-Confidence on Gender Role Stress and Willingness to Pursue a Career in Tourism: A Study on Students Studying in Tourism Departments)
Authors: ÖZALTAŞ SERÇEK Gülseren , ALTÜRK Vahap , ARIK YÜKSEL Tuğba
Published: January 2025

Toplumsal cinsiyet rolleri toplum tarafından bireyden beklenenler ile ilgilidir. Kadının toplumsal cinsiyet rolleri ise oldukça farklılaşmaktadır. Bu roller kadınlarda strese sebebiyet verebilmekte ve kadınların karar süreçlerini de etkileyebilmektedir. Bu çalışmada, öz güvenin kadın toplumsal cinsiyet rol stresi ve turizmde kariyer yapma isteği üzerindeki etkisi incelenmektedir. Araştırmada ilişkisel tarama modeli kullanılmıştır. Çalışma evrenini turizm eğitimi alan kadınlar oluşturmaktadır. Araştırma kapsamında 458 kişiye ulaşılmıştır. 458 kişiden elde edilen verilerden düzensiz ve eksik doldurulan 50 anket veri setinden çıkarılarak analizlere 408 anket üzerinden devam edilmiştir. Araştırma sonucunda, toplumsal cinsiyet rolünün öz güven ve turizmde kariyer yapma isteği üzerinde anlamlı bir etkiye sahip olmadığı belirlenmiştir. Öz güvenin kariyer yapma isteğini anlamlı bir şekilde arttırdığı yani öz güveni daha yüksek olan öğrencilerin turizmde kariyer yapma isteğinin daha fazla olduğu tespit edilmiştir. Bu çalışma kadınların turizmde çalışmasını desteklemek ve turizmde kariyer yapmalarını sağlamak için öncelikle öz güvenlerini arttırmanın önemli olduğunu göstermektedir.
Gastronominin Duygusal Bileşenleri Ölçeği nin Türkçe ye Uyarlama Çalışması (The Turkish Adaptation of the Affective Components of Gastronomy Scale)
Authors: TAŞKIN Grant Altay
Published: January 2025

Gastronomi, turizmin en önemli unsurlarından birisi haline gelmiş ve turistlerin seyahat motivasyonları arasında üst sıralarda kendisine yer bulmuştur. Bu kapsamda bir turistin gastronomi deneyimlerinden ortaya çıkan hislerin ve duyguların tespit edilmesi oldukça önemlidir. Bu araştırmanın amacı İngilizce dilinde geliştirilmiş olan beş maddeli Gastronominin Duygusal Bileşenleri Ölçeği’nin (Affective Components of Gastronomy) Türkçe’ye uyarlamasını yaparak geçerlik ve güvenilirlik analizlerini gerçekleştirmektir. Bu amaç doğrultusunda İngilizce dil bilimi uzmanları ve turizm akademisyenleri tarafından çeviri ve geri çeviri çalışmaları gerçekleştirilmiş; ardından pilot çalışma, keşfedici faktör analizi ve doğrulayıcı faktör analizi ile ölçeğe son hali verilmiştir. Ölçeğin Türkçe uyarlaması dört madde ve tek boyuttan oluşmaktadır. Yapılan analizler sonucunda ölçeğin Cronbach’s Alpha değeri ve faktör yükleri açısından sorunsuz olduğu tespit edilmiştir. Doğrulayıcı faktör analizi sonucunda uyum iyiliği değerlerinin tümü mükemmel uyum göstermiştir. Ölçeğin ayrıca AVE değeri ve CR değeri de kabul edilen eşik değerinin üzerindedir. Bu sonuçlar doğrultusunda Türkçe’ye uyarlanan Gastronominin Duygusal Bileşenleri Ölçeği’nin geçerli ve güvenilir bir ölçme aracı olduğu ortaya konmuştur.
Endüstriyel Kenevirin Gastronomik Değeri: Yeni Ürünlerin Geliştirilmesi, Çeşitlendirilmesi ve Tüketici Beğenisinin Ölçülmesi (The Gastronomic Value of Industrial Hemp: Development, Diversification, and Consumer Acceptance of Novel Products)
Authors: KAZKONDU İhsan , KESGİN Erol , GÖKYAR Mustafa , YILMAZ CAN Emine
Published: January 2025

Bu çalışmada ekim izni bulunan Zonguldak’ta endüstriyel kenevirin yağı, unu, kenevir kalbi ve tohumu kullanılarak sosyo-ekonomik ve kültürel gelişmeye katkı sağlayacak gastronomik ürünler geliştirmek ve çeşitlendirmek, çeşitlendirilen ürünlerin tüketiciler arasında beğeni düzeylerini ortaya çıkarmak amaçlanmıştır. Araştırma kapsamında, endüstriyel kenevirden farklı tüketim alanları için 10 çeşit gastronomik ürün geliştirilmiştir. Geliştirilen gastronomik ürünlerin beğeni düzeylerini ortaya koymak için deneysel analiz yöntemine başvurularak eğitim almış olan 40 kişilik panelist grup tarafından duyusal analizler gerçekleştirilmiştir. Elde edilen duyusal veriler SPSS 22.0 programında analiz edilerek, geliştirilen gastronomik ürünlerin beğeni düzeyi ortalamaları ve beğeni yüzde frekansları saptanmıştır. Sonuç olarak panelistler tarafından en çok beğenilen ilk üç gastronomik ürün sırasıyla; kenevir vinaigrette soslu domatesli kenevir bruschetta, kenevir kalpli fırınlanmış helva ve kenevir kalpli çikolata olmuştur. Bu sonuçlar, endüstriyel kenevirin gıda sektöründe inovatif ve katma değerli ürünler geliştirmek için önemli bir kaynak olduğunu göstermektedir. Elde edilen sonuçlar neticesinde endüstriyel kenevirin besleyici özellikleri ve çok yönlü kullanım olanakları hem tüketici taleplerini karşılama hem de kırsal kalkınmayı destekleme potansiyeline sahip olduğunu göstermektedir.
Kapadokya Bölgesinin Sürdürülebilir Kalkınma Açısından Değerlendirilmesi: Turizm Sektörü (Evaluation of Cappadocia Region in Terms of Sustainable Development: Tourism Sector)
Authors: ÇAMLICA Koray
Published: January 2025

Çalışma, Kapadokya bölgesinin turizm sektörünü, geleneksel büyüme odaklı paradigmalardan bütüncül bir sürdürülebilirlik modeline geçerek sürdürülebilir kalkınma bağlamında değerlendirmektedir. Bulgular, bölgenin eşsiz doğal ve kültürel mirasının hem bir fırsat hem de bir zorluk teşkil ettiğini ve ekonomik büyüme, çevrenin korunması ve sosyal eşitliğin dengelenmesi için stratejik eylem gerektirdiğini göstermektedir. SWOT analizi kullanan çalışma, Birleşmiş Milletler Sürdürülebilir Kalkınma Amaçları (SKA) doğrultusunda temel güçlü yönleri, zayıf yönleri, fırsatları ve tehditleri tanımlamaktadır. Öneriler arasında yenilenebilir enerji çözümlerinin uygulanması, alternatif turizmin teşvik edilmesi ve toplum katılımının artırılması yer almaktadır. Çalışma, Kapadokya'nın dirençli ve küresel olarak rekabetçi bir sürdürülebilir turizm destinasyonuna dönüşümünü destekleyerek paydaşlar için eyleme geçirilebilir içgörüler sağlayarak literatüre ve uygulamaya katkıda bulunmaktadır.