bluuebunny/crossref_metadata_2025 huggingface dataset:
HUBUNGAN PENGETAHUAN IBU TERHADAP TINGKAT PARTISIPASI MASYARAKAT (D/S) DI POSYANDU DESA BAYA BETUNG WILAYAH KERJA PUSKESMAS PANDAN KECAMATAN SUNGAI TEBELIAN KABUPATEN SINTANG
Authors: Nurmaida Silalahi Ellys , Hariyadi Didik
Published: November 2019

Posyandu is one of the Efforts the health community’s Power Stems (UKBM) which is managed and organized from, by, for and with communities in implementing health development. UKBM can empower communities and provide convenience to the public in obtaining basic health services to accelerate the decline in the death rate of mothers and babies. This research aims to know the mother’s knowledge, the relationship with the level of participation of the community in the village of Posyandu Baya Betung working area Pandan River Subdistrict health centers Tebelian Regency Sintang. This type of research is observational design with Cross Sectional (Pieces of latitude). The research was carried out in the village of Baya Betung working area Pandan Tebelian River Subdistrict health centers on December 29, s/d January 3, 2015. The respondents in this study were the mother of a toddler. How to use data collection interviews using questionnaire instruments. The results showed no relationship between mother’s knowledge (p = 0.05) with the level of participation of the community in the village of Baya Betung working area Pandan River Subdistrict health centers Tebelian Regency Sintang. It is recommended to provide guidance about the benefits to mother and toddler posyandu layout posyandu is close to the community.
GAMBARAN UMUM SISA MAKANAN DAN STATUS GIZI PADA PASIEN HIPERTENSI YANG MENERIMA DIET RENDAH GARAM DI RUMAH SAKIT SULTAN SYARIF MOHAMAD ALKADRIE PONTIANAK
Authors: Welviana Isabelita , Waliyo Edy
Published: November 2019

Low-salt diets affect the patient’s appetite because restricted salt will affect the taste of food. A decrease in appetite due to the taste of food causes the patient not to consume the portion of food served which results in his nutritional needs not being met. This study aims to determine the general description of food residue and nutritional status in hypertensive patients who receive a low-salt diet at Sultan Syarif Mohamad Alkadrie Pontianak Hospital, the type of research used was descriptive with cross sectional design, the number of samples studied were 41 people. The data used consisted of two types, namely primary data including nutritional status data based on BMI, identity data and food waste data. While secondary data covers the general state of the sample research location. The results showed that respondents who had a good food intake of 43.9% and those who had less food intake were 56.1%. The most common type of leftovers found in respondents were animal dishes at 41%. It was found that respondents with overweight nutritional status were 14.6% (6 people) and underweight nutritional status of 19.6 (8 people). It is advisable to further improve the type and taste of food, so that patients do not get bored quickly and are able to spend the food given by the hospital, so that nutritional status the patient is awake during hospitalization.
PEMBUATAN MINUMAN SARI TEMPE DENGAN EKSTRAK JERUK SIAM (Citrus Nobilis) DITINJAU DARI MUTU ORGANOLEPTIK KADAR VITAMIN C DAN KADAR AKTIVITAS ANTIOKSIDAN ISOFLAVON
Authors: Kharisma Purry Ajeng Pridya , Rafiony Ayu
Published: November 2019

Tempe is a processed soy product that has been experiencing a decline in odor as a result of fermentation. Tempe juice beverage is one example of product diversification of food products based on tempe. Siam is one of the local fruits that are quite popular by the community and become the main commodity in West Kalimantan. In the process of making tempe juice, need to add a stabilizer CMC (Carboxy methyl cellulose) as much as 0.25% to produce quality tempe juice. The purpose of this research is to know the making of tempe juice extract with orange extract of siam (citrus nobilis) in terms of organoleptic quality, vitamin C level and isoflavone antioxidant activity level. The research method used experiment with 3 treatment of Siam orange extract 30%, 40% and 50%. The panelists used in the study were slightly trained panelists totaling 25 people. Based on statistical test, there is no effect of making tempe juice with orange extract (citrus nobilis) in terms of organoleptic quality based on color, flavor and taste. Due to the color -0.10 <3.23, the aroma is 2.42 <3.23 and the flavor is 0.17 <3.23. The results of this research is the addition of 50% more siam orange extract can be accepted by panelists. The results of this beverage viscosity were 30% concentration 0.40 dpas, 40% 0.34 dpas and 50% 0.32 dpas. Vitamin test results showed vitamin C content in tempe juice is 56.556 mg / 250 ml sample. Based on the results of isoflavone antioxidant activity test showed antioxidant levels 23%. Can be recommended as one of the beverages that contain antioxidants and vitamin C to meet the needs of the day and need to do further research on the storage power of tempe juice with the addition of orange extract.
EFEKTIFITAS PENGGUNAAN MEDIA EDUKASI BUKU SAKU DAN LEAFLET TERHADAP PENGETAHUAN DAN KEPATUHAN DIET PASIEN RAWAT JALAN DIABETES MELITUS TIPE 2 DI PUSKESMAS
Authors: Hidayah Muniratul , Sopiyandi Sopiyandi
Published: November 2019

Educational activities is one strategy to the management of diabetes mellitus. Education is the activity of delivering health messages to groups or individuals in order to gain a better knowledge. The selected media is pocket books and leaflets, booklets chosen because it is simple, brief, and contains a lot of information. The purpose of this study to determine the effectiveness of the use of educational media pocket books and leaflets on knowledge and dietary compliance of outpatients with diabetes mellitus type 2 in the clinic. The research is a Quasi-Experiment with design used is Pretest-Posttest designnamely in the two groups conducted a pretest to determine the initial state before being given a different treatment, and both were also given the posttestusing the Wilcoxon test and Mann-Whitney test with a significance level of = 0.05. The results showed no significant differences in knowledge after being given nutrition education with media pocket books and leaflets p value. knowledge of 0,000 (Sig. <0.05), whereas the p values   obtained compliance. amounted to 0,641 (p. <0.05) showed no significant difference in adherence respondents after being given nutrition education with media pocket books and leaflets. It is concluded that there are differences in knowledge after being given nutrition education with media pocket books and leaflets. However there was no difference in compliance after being given nutrition education with media pocket books and leaflets.
PENGARUH KONSUMSI BUAH SEMANGKA MERAH (Citrullus Vulgaris Schard) TERHADAP PENURUNAN TEKANAN DARAH PADA PENDERITA HIPERTENSI RAWAT JALAN DI WILAYAH PUSKESMAS PERUMNAS I PONTIANAK BARAT
Authors: Hutasoit Hermina Roselita , Waliyo Edy
Published: November 2019

Hypertension is a disorder of the blood vessels that result in oxygen supply and nutrients carried by the blood obstructed to the body tissues that need it (Vitahealth, 2006). Consumption of a diet high in fruits and vegetables, reduced sodium intake and increased potassium intake in foods can reduce the incidence of hypertension (Houston, Harper & PharmD, 2008). This study aims to determine the effect of red watermelon consumption on the decrease in blood pressure in hypertensive patients outpatient in Puskesmas Perumnas I West Pontianak. This type of research is experimental with quasi experiment design with pretest-posttest control group design. The test used is chi square test, paired t-test, wilcoxon, oneway anova and kruskal-wallis. The number of samples studied was 42 samples and the time of the research was conducted on June 2018. The results of the red watermelon in patients with hypertension with a dose of 200 gr, 250 gr and 300 gr for 4 days can lower blood pressure. The average of derivation in systolic blood pressure in the 200 gr group was -10,71 mmHg and diastolic -8,21 mmHg, average of derivation systolic blood pressure in the 250 gr group of -12,86 mmHg and diastolic -9,99 mmHg while the systolic blood pressure average of derivation in group 300 gr for -15,71 mmHg and diastolic equal to -13,57 mmHg. Suggestions in this study respondents can consume watermelon fruit as an alternative to lower blood pressure as much as 300 grams and for subsequent researchers need an additional length of time intervention to see the effect of decreased blood pressure is systolic blood pressure and diastolic responders to normal.
Meningkatkan Hasil Belajar Siswa dengan Media Buta (Gabus Pita)
Authors: Tobing Intan Mustika Yulias , Ainy Chusnal , Suprapti Endang
Published: November 2019

Kriteria ketuntasan minimum (KKM) SMP Muhammadiyah 5 Surabaya kelas VII adalah 80 dan siswa yang tuntas belajar sebanyak ≥80%. Permasalahan yang terjadi di kelas VII-I SMP Muhammadiyah 5 Surabaya adalah nilai rata-rata siswa ≤ KKM. Ini terlihat dari 20 siswa, hanya 2 siswa yang tuntas atau 10%, sementara 18 siswa tidak tuntas belajar atau sebesar 90%, skor rata-rata adalah 55,55.Penelitian ini menggunakan pembelajaran menggunakan media BUTA (Cork Ribbon). Sampel penelitian ini adalah siswa kelas VII-I SMP Muhammadiyah 5 Surabaya. Penelitian ini adalah penelitian tindakan kelas (PTK) dengan pelaksanaan 2 siklus.Dari hasil penelitian pada siklus I dapat disimpulkan bahwa hasil belajar siswa kelas VII-I mengalami peningkatan. Hal ini dapat dilihat dari kelengkapan siswa sebelum tindakan 10% atau 2 siswa meningkat menjadi 55% atau sebanyak 11 siswa yang tuntas. Sedangkan siklus kedua 85% atau 17 siswa tuntas dengan rata-rata 87,55.
Gambaran Anti-Plasmodium sp. Pada Anggota Tentara Nasional Indonesia Angkatan Darat Di Kota Cimahi
Authors: Naully Patricia Gita , Khairinisa Gina , Saputri Dewi Ratih
Published: November 2019

Malaria is a disease caused by Plasmodium sp. The presence of such parasites in body can be characterized by the presence of anti-Plasmodium sp. antibodies. Malaria cases are still prevalent in Indonesia and generally occur in people who travel to endemic areas. One of the jobs that obliges its members to serve to various regions, including endemic areas is the Indonesian Army (TNI AD). Many Army personnel residing in Cimahi City. The purpose of this study is to determine the overview of malaria in members of the Army in Cimahi City. This study used a sample of 30 TNI AD who are residing in Cimahi City and have been assigned to various regions in Indonesia. Venipucture is only performed on respondents who have signed informed consent and filled out the interview form. Malaria screening is performed using immunochromatography that can detect anti-P. vivax and anti-P. falciparum antibodies, with a high degree of sensitivity and specificity. Of the 30 people, there were 4 people (13.3%) who had been infected with malaria and 2 (6.7%) of whom had experienced mixed malaria. All respondents who tested positive for malaria claimed to have been assigned to malaria endemic areas such as Papua and Maluku for several years.
Utility of Automated Feeding Data to Detect Social Instability in a Captive Breeding Colony of Rhesus Macaques (Macaca mulatta): A Case Study of Intrafamily Aggression
Authors: Johnston Juliane R , Meeker Tracy L , Ramsey Jacklyn K , Crane Maria M , cohen Joyce k , Ethun Kelly F
Published: November 2019

Some captive breeding colonies of rhesus macaques live in large outdoor multimale, multifemale social groups. These groups are composed of several matrilineal families, governed by a clear female dominance hierarchy. Aggression within the same or between different matrilineal families
due to social instability can result in trauma and mortality. Therefore, a primary management goal is to detect emerging social unrest before the onset of significant fighting and wounding. Accordingly, groups are monitored routinely for changes in dominance and alliance relations as well
as for increases in trauma frequency and severity. Decreased food intake is a normal physiologic response to acute stress; therefore, inappetence in key animals or groups of monkeys might be used as an indicator of increased social stress and emerging instability. An incident of intrafamily
aggression occurred recently in a breeding group at our facility and resulted in considerable fighting. Because this compound was equipped with an automated feeding system that tracks the caloric intake of individual animals, we retrospectively analyzed feeding data to determine whether significant
reduction in caloric consumption occurred prior to the onset of aggression, compared with baseline values. Neither the entire group nor individual families showed any significant differences in total caloric intake between baseline and previous 24 h values; however, the affected family exhibited
a 20% reduction in total caloric during the 24 h prior to the aggression. Most notably, the deposed subfamily showed a marked 58% reduction in caloric intake during the prior 24 h, whereas remaining subfamilies showed no significant changes in intake. High-ranking animals of the group, including
the α female, β female, and α male, similarly exhibited marked decreases in caloric intake during that period. These findings indicate that automated feeders can assist management staff with monitoring social stability in breeding colonies of rhesus macaque.
Ülkemiz Kültür Bitkilerinden Persea americana Mill. (Avokado) ve Tıbbi Açıdan Değerlendirilmesi
Authors: TAVLI Ömerül Faruk , EROĞLU ÖZKAN Esra
Published: November 2019

Persea
americana meyveleri (avokado), 1500’lü yılların
başlarına kadar sadece Amerika yerlileri tarafından tüketilirken, Amerika
Kıtası’nın keşfiyle Avrupa tarafından tanınmış, sonrasında tüm dünyaya
yayılmıştır. Ülkemizde, meyvelerin besin olarak tüketiminin yaygınlaşması ve
ticari önem kazanması son yıllarda artış göstermiştir, ancak bitkinin kültüre
alınması 1980’li yıllara dayanmaktadır. Günümüzde, özellikle Antalya, Mersin ve
Hatay bölgelerinde P. americana
türünün birkaç varyetesi yetiştirilmektedir. İçerdiği mineraller (özellikle
potasyum), vitaminler (özellikle E ve C vitaminleri), protein, fitosteroller ve
yağ asitleriyle zengin bir kaynak olan avokado üzerinde yapılmış birçok çalışma
bulunmaktadır. Yapılan in vitro çalışmalar, yaprak ekstrelerinin anti-HIV, sitotoksik ve insektisidal  etkiye; çekirdek yağının gastroprotektif, antihelmintik
ve antioksidan etkiye; meyvenin ise antibakteriyel etkiye sahip olduğunu
göstermektedir. Bu çalışma ile P. americana
türünün kimyasal bileşimi, tıbbi etki ve kullanılışı üzerine yapılmış
araştırmaların derlenmesi, Türkiye’de yetişen  varyetelerin
öneminin vurgulanması ve tıbbi potansiyelinin değerlendirilmesi amaçlanmıştır.
Elde edilen bulgular Akdeniz bölgemizin toprak ve iklim koşullarının içerik
açısından zengin bitkiler yetişmesine uygun olduğunu, bu bitkinin tıbbi açıdan
değerlendirilmesi için ileri çalışmaların yapılması gerektiğini göstermektedir.
Perancangan jaringan menggunakan CISCO
Authors: Sembiring Ewa Haris
Published: November 2019

Perancangan jaringan pada SMKN 1 MINAS menggunakan cisco
“May the philosophers of existence do better next time”! Canguilhem, Life and death’s end.
Authors: Akmut Camille
Published: November 2019

Leftover translations from Vie et mort de Jean Cavailles.
Linking the installation response of screw piles to soil strength and ultimate capacity
Authors: Hambleton James , Stanier Sam
Published: November 2019

A perceived advantage of screw-type foundations is the ability infer aspects of foundation performance from quantities measured or observed during installation, especially the installation torque. A particular concept widely used in practice is to correlate installation torque to ultimate capacity. This notion has proven useful as a field verification technique despite the absence of validated models that relate key variables of interest, such as installation torque, axial (crowd) force, geometrical parameters, and soil strength. This paper considers previous work by the co-authors and collaborators on analytical, numerical, and physical modelling of screw piles to relate the quantities measured or controlled during installation (e.g., installation torque) to the ultimate capacity and soil strength. Attention is given to saturated clay as a particular soil type amenable to simplified analysis. An analytical model for a single-helix pile is considered as a means of directly relating the ultimate capacity and undrained shear strength to the installation torque, crowd force, plate pitch, plate diameter, shaft diameter, installation depth, and surface roughness. The connection between the installation variables and ultimate capacity—and the sensitivity to crowd force in particular, a quantity that is typically not measured during field installations—is also discussed. The theoretical predictions are compared against data obtained from small-scale laboratory experiments that suggest the installation torque relates to the remolded strength of the soil.
Pengaruh Motivasi Terhadap Kinerja Karyawan
Authors: Norhadiana
Published: November 2019

Perusahaan atau lembaga karena memiliki peran sebagai penggerak seluruh aktifitas dalam mengelolah, mengatur,dan menjalankan kegiatan suatu perusahaan atau lembaga Dalam hal ini motivasi yang kuat dan kepuasan kerja sangat mempengaruhi kinerja karyawan. Pimpinan dapat memotivasi bawahannya untuk meningkatkan kinerjanya dengan cara mengevalusi kinerjanya, menaikkan gajinya, pemberian bonus /penghargaan dan kesempatan. Untuk memotivasi karyawan, manajer harus mengetahui motif dan motivasi yang diinginkan karyawan Penelitian ini bertujuan untuk mengetahui:(1)motivasi kerja (2)pengaruh motivasi kerja terhadap kenerja karyawan. Tenaga kerja yang berkulitas akan menghasilkan suatu hasil kerja yang optimal sesuai dengan target kerja. Variable dalam jurnal ini terdiri dari variable bebas berupa motivasi kerja yang terdiri dari kebutuhan eksistensi , kebutuhan hubungan, dan kebutuhan pertumbuhan. Sumber daya manusia (SDM) sangat penting bagi.
Language-specific numerical estimation in bilingual children
Authors: Marchand Elisabeth , Wade Shirlene , Sullivan Jess , Barner David
Published: November 2019

We tested 5- to 7-year-old bilingual learners of French and English (N = 91) to investigate how language-specific knowledge of verbal numerals affects numerical estimation. Participants made verbal estimates for rapidly presented random dot arrays in each of their two languages. Estimation accuracy differed across children’s two languages, an effect which remained when controlling for children’s familiarity with number words across their two languages. Also, children’s estimates were equivalently well ordered in their two languages, suggesting that differences in accuracy were due to how children represented the relative distance between number words in each language. Overall, these results suggest that bilingual children have different mappings between their verbal and non-verbal counting systems across their two languages and that those differences in mappings are likely driven by an asymmetry in their knowledge of the structure of the count list across their languages. Implications for bilingual math education are discussed.
Intuitions about the Reference of Proper Names: A Meta-Analysis
Authors: van Dongen Noah N'Djaye Nikolai , Colombo Matteo , Romero Felipe , Sprenger Jan
Published: November 2019

The finding that intuitions about the reference of proper names vary cross-culturally (Machery et al., 2004) was one of the early milestones in experimental philosophy. Many follow-up studies investigated the scope and magnitude of such cross-cultural effects, but our paper provides the first systematic meta-analysis of replications of that original study. In the light of our results, we assess the existence and significance of cross-cultural effects for intuitions about the reference of proper names.
School characteristics and children’s mental health: A linked survey-administrative data study
Authors: Patalay Praveetha , O'Neill Erin , Deighton Jessica , Fink Elian
Published: November 2019

Background. Mental health difficulties are childhood-onset with lifelong consequences. Children spend a large proportion of their daily life in schools, making the school setting an important context for mental health prevention and support. Methods. Data from a large-scale mental health survey were linked to the national pupil and school census databases. Data from 23,215 children from 648 primary schools were analysed to examine the associations of school composition (school size, gender, socioeconomic and ethnicity composition) and school climate with emotional and behavioural symptoms, as well as high mental health difficulties (scores above clinical cut-off). The proportion of school-level variation explained by composition and climate and whether the association of school factors with mental health were moderated by child-level socio-demographic characteristics were also investigated. Results. After controlling for child-level characteristics, 3 to 4.5% of the variation in children’s mental health outcomes could be attributed to schools. Of this, small proportions were explained by school composition (1.4 to 3.8%) and larger proportions were explained by differences in school climate (29.5 to 48.8%). In terms of composition, lower school socio-economic status (SES) was associated with higher mean behavioural symptoms and slightly raised odds of high mental health difficulties (OR = 1.05, 95% CI: 1.01,1.09). More positive school climate was associated with lower mean emotional and behavioural symptoms and lower odds of mental health difficulties (OR = 0.78, 95% CI: 0.74, 0.81). Some of the associations between school factors and mental health were moderated by child sex and SES.Conclusion. School composition was for the most part not associated with children’s mental health and explained only a small proportion of the between school variation in mental health. School deprivation was the only compositional variable to be associated with poor mental health and its association was moderated by the child’s socio-economic status. School climate explained a large amount of the between-school variation in mental health and appears a good target for universal prevention of mental health difficulties in children.
The Development of CT-S Learning Module on The Linear Motion Topic to Promote Computational Thinking Thinking
Authors: Khasyyatillah Isra , Osman Kamisah
Published: November 2019

Computational Thinking (CT) is the main skill of the 21st century that is increasingly attracting more researchers to study how to implement CT in the learning and teaching process. Among the CT tools that can be used to develop CT is programming. Currently, availability and easily accessible programming tools have led researchers and educators to explore how to introduce CT in the context of learning and teaching in schools. Recognizing the importance of implementing CT in the classroom, this study aims to develop the CT-S (Computational Thinking and Scratch) module for the Linear Motion topic. The type of this study is research and development research to develop modules based on the ADDIE model to produce the CT-S module with validity and reliability. Data were analyzed using descriptive statistical analysis. The result showed that the CT-S module was valid. It is eligible to be used as the instructional material of Physics. This study implies that computational thinking skills can be integrated with other subjects besides computer science like physics. Therefore, teachers can design lessons that are relevant to the context and students' characteristics.
REMOTE CONTROL OF HERMETICITY MAGISTRAL GAS PIPELINES
Authors: Martyniuk R. T.
Published: November 2019

It is known, that in the process of exploitation of main gas pipelines there are violations of impermeability, which show up as effluences of gas in surrounding, creating the threat of contamination of environment and are potentially dangerous for the origin of refusals of the system. On the surface of – rountou such effluences have the displays as temperature anomalies on a natural temperature background and anomaly of concentrations of hydrocarbons. Unlike the anomalies of other origin, in the area of effluence they practically do not rely on spatial co-ordinates and time.
KINEMATICS OF A ROLLER CONE BIT WITH A DIRECT FACET TOOTH
Authors: Berezhnytskyi B. S. , Vorobyov M. S.
Published: November 2019

The advanced technique of shock-kinematic analysis of the bit roller cone interaction with rock in the process of oil and gas wells drilling is proposed. Preliminary investigations of the interaction of the roller cone bits with rock were based on assumptions far from reality: the concept of the instantaneous axis of rotation of the roller cone constant contact with rock, the absence of slipping, as well as the tooth reforming and sinking into rock. The principle of the roller cones action is the gradual destruction of the surface of the bottomhole due to the cutting-crushing chipping of rock with a bit tooth.The axial roller cone is considered, and the original method of planes projection is used to determine the regulation of tooth motion, taking into account: bit roller cones slipping along the surface of the bottomhole; phases of roller cone tooth sinking into rock; real change in the distance of the axis of rotation of the roller cone to the surface of the bottomhole due to tooth penetration into the rock; the substantiation of the conditions for avoiding the roller cone tooth entering to the previously obtained hole in the process of bottomhole crushing. Besides the moment of the drill string inertia, the moments of roller cones inertia are additionally taken into account under the condition of the oblique impact of the tooth on the rock.The technique allows to calculate the volume of the disintegrated rock on the bottomhole, both taking into account and without taking into account rock chipping and tooth forming. The obtained dependencies allow us to select transmitted ratios from the drill string to the crowns of the roller cones under the condition of avoiding the roller cone tooth to the previously obtained hole during rock destruction on the bottomhole. It allows increasing the efficiency of drilling by roller cones.
REVOLUTION AND STATUS OF WOMEN: GENDER AND POLITICAL ASPECTS
Authors: Kobets Y. V.
Published: November 2019

The twentieth century will be remembered as a time of the revolutions that had a consequence a radical transformation of social relations. There was also a so-called "Quiet revolution" or "revolution of women", which led to a significant number of their emancipation. The article deals with the change of gender stereotypes under the influence of revolutionary changes during the year ot 1917, the period of formation the establishment of independence, during the events of the Maidan and the Revolution of Virtue.

The research document contains a political analysis of socio-political processes of participation and role of women that took place in Ukraine and in the world. The author emphasizes the features of the displaying problems depending on a particular ideological and political situation, political regime. It became possible with the help of a systematic and integrated approach to consideration of the problem to supplement the general picture of revolutionary events, to reveal the female component of these periods in all of it's diverse manifestations, to make a certain contribution to the field of gender research in political science.

The focus is on the struggle for women to equalize rights with men in the economic, political, cultural spheres of life, as well on their participation in general political processes.
Étude in vitro des propriétés antioxydante, antiproliférative et antimicrobienne de Salvia clandestina du Maroc
Authors: Et-Touys A. , Bouyahya A. , Bourais I. , Dakka N. , Bakri Y.
Published: November 2019

L’objectif de cette étude vise l’évaluation in vitro de l’activité antioxydante, antiproliférative et antimicrobienne des extraits organiques Salvia clandestina du Maroc. L’effet antioxydant est estimé par le test de balayage du radical DPPH. L’activité antiproliférative est évaluée sur deux lignées cellulaires cancéreuses en utilisant le test MTT. L’activité antimicrobienne est évaluée contre Escherichia coli, Staphyloccocus aureus et Listeria monocytogenes. L’extrait d’hexane et de dichlorométhane ont montré des capacités antioxydantes à l’IC50 = 118,28 ± 2,108 et 191,36 ± 2,72 μg/ml, respectivement. Alors que l’extrait méthanolique a montré une remarquable activité antiproliférative contre la lignée RD (IC50 = 86,24 μg/ml). Concernant l’activité antimicrobienne, les extraits hexanique et méthanolique sont plus actifs, alors que Staphylococcus aureus s’est montré la plus sensible. Vu les résultats obtenus, Salvia clandestina pourrait être considérée comme une source importante de molécules bioactives. Cependant, d’autres investigations sont nécessaires regardant les principes actifs responsables des effets pharmacologiques obtenus ainsi que l’investigation de l’action antibactérienne et anticancéreuse.
Équité environnementale et accessibilité aux parcs à Ho Chi Minh Ville (Vietnam)
Authors: Hoang Anh Tu , Apparicio Philippe , Pham Thi-Thanh-Hien
Published: November 2019

L’objectif de cet article est de poser un diagnostic d’équité environnementale quant à l’accessibilité aux parcs à Ho Chi Minh Ville (HCMV) pour quatre groupes de population (les enfants, les personnes âgées, les personnes faiblement et hautement scolarisées). Pour ce faire, deux mesures d’accessibilité calculées à partir de la distance réticulaire sont mises en œuvre dans les SIG : la distance au parc le plus proche (proximité immédiate) et la méthode du enhanced two-step floating catchment area (disponibilité en fonction de l’offre et de la demande). Puis, plusieurs modèles de régression sont construits avec, comme variables dépendantes, les mesures d’accessibilité et, comme variables indépendantes, les pourcentages des quatre groupes. Les résultats montrent que l’accessibilité aux parcs est très faible à HCMV : en moyenne, les habitants résident à 1,879 kilomètre du parc le plus proche et on retrouve uniquement 0,286 hectare de parc pour 1 000 habitants dans un rayon de deux kilomètres. De plus, les jeunes enfants subissent une double iniquité avec de plus faibles proximité et disponibilité de parcs comparativement au reste de la population.
Experimental study of the stability and synthesis of the tourmaline supergroup minerals
Authors: Setkova T. V. , Balitsky V. S. , Shapovalov Yu. B.
Published: November 2019

Tourmaline is one of the most widespread minerals in nature and one of the most popular gems and promising piezoelectric material. The growth of large crystals is today a topical task. With the growth of tourmaline single crystals appears problems associated with its complex chemical composition, high chemical stability in hydrothermal solutions and a low growth rate. The paper reviews of recent work on the tourmaline synthesis and the results obtained in IEM RAS.
A New Serum Biomarker Set to Detect Mild Cognitive Impairment and Alzheimer’s Disease by Peptidome Technology
Authors: Abe Koji , Shang Jingwei , Shi Xiaowen , Yamashita Toru , Hishikawa Nozomi , Takemoto Mami , Morihara Ryuta , Nakano Yumiko , Ohta Yasuyuki , Deguchi Kentaro , Ikeda Masaki , Ikeda Yoshio , Okamoto Koichi , Shoji Mikio , Takatama Masamitsu , Kojo Motohisa , Kuroda Takeshi , Ono Kenjiro , Kimura Noriyuki , Matsubara Etsuro , Osakada Yosuke , Wakutani Yosuke , Takao Yoshiki , Higashi Yasuto , Asada Kyoichi , Senga Takehito , Lee Lyang-Ja , Tanaka Kenji
Published: November 2019

Background:

Because dementia is an emerging problem in the world, biochemical markers of cerebrospinal fluid (CSF) and radio-isotopic analyses are helpful for diagnosing Alzheimer’s disease (AD). Although blood sample is more feasible and plausible than CSF or radiological biomarkers for screening potential AD, measurements of serum amyloid- β (Aβ), plasma tau, and serum antibodies for Aβ1 - 42 are not yet well established.

Objective:

We aimed to identify a new serum biomarker to detect mild cognitive impairment (MCI) and AD in comparison to cognitively healthy control by a new peptidome technology.

Methods:

With only 1.5 μl of serum, we examined a new target plate “BLOTCHIP®” plus a matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF/MS) to discriminate control ( n = 100), MCI ( n = 60), and AD ( n = 99). In some subjects, cognitive Mini-Mental State Examination (MMSE) were compared to positron emission tomography (PET) with Pittsburgh compound B (PiB) and the serum probability of dementia (SPD). The mother proteins of candidate serum peptides were examined in autopsied AD brains.

Results:

Apart from Aβ or tau, the present study discovered a new diagnostic 4-peptides-set biomarker for discriminating control, MCI, and AD with 87% of sensitivity and 65% of specificity between control and AD (*** p < 0.001). MMSE score was well correlated to brain Aβ deposition and to SPD of AD. The mother proteins of the four peptides were upregulated for coagulation, complement, and plasticity (three proteins), and was downregulated for anti-inflammation (one protein) in AD brains.

Conclusion:

The present serum biomarker set provides a new, rapid, non-invasive, highly quantitative and low-cost clinical application for dementia screening, and also suggests an alternative pathomechanism of AD for neuroinflammation and neurovascular unit damage.
Effect of environmental music on autonomic function in infants in intensive and growing care units
Authors: Hasegawa Y. , Hoshiyama M.
Published: November 2019

BACKGROUND:

The aim of this study is (1) to observe the effect of the background music (BGM) in the incubator on heart rate variability (HRV) during the first few weeks of life in preterm infants in the neonatal intensive (NICU) and growing care units (GCU) and (2) to investigate the effect of environmental music on autonomic function in the infants.

METHODS:

Thirty infants, including premature (26 3/7 – 38 4/7 weeks) and low-birth weight (LBW) (946–2,440 g) infants, admitted to the NICU or GCU were involved. The heart rate, low- (LF, 0.05–0.15 Hz) and high- (HF, 0.15–0.4 Hz) frequency HRV components, and LF/HF ratio were measured. The BGM, lullabies for a baby, was delivered through a speaker in the incubator, and the HRV components were compared among before, during, and after intervention with BGM.

RESULTS:

The mean HR did not change among the experimental conditions. The LF and HF values decreased during the BGM condition, but not LF/HF, compared with the condition before BGM.

CONCLUSIONS:

The present results showed that an auditory environment affected the autonomic function of infants with a range of BGM in the NICU/GCU. The present study also suggested that BGM, a non-invasive and non-pharmacological intervention, could be an evaluation tool for autonomic function in infants in NICU/GCU.
Is the type of neuraxial anesthesia associated with adverse neonatal outcomes among patients with preeclampsia?
Authors: Beamon C.J. , Stuebe A.M. , Edwards L.J. , Mayer D.C. , Strauss R.A.
Published: November 2019

OBJECTIVE:

Both preeclampsia and neuraxial anesthesia can alter placental perfusion, potentially affecting the neonatal status. The objective of our study is to quantify the association between type of neuraxial anesthetic and short-term neonatal morbidity among preeclamptic patients undergoing cesarean delivery.

METHODS:

We performed a secondary analysis of a prospective observational cohort study. Women with singleton gestations and a diagnosis of preeclampsia who underwent cesarean delivery with neuraxial anesthesia were included in the analysis. Short-term neonatal morbidities, defined as neonatal intensive care unit (NICU) admission, arterial cord gas pH ≤7.2 and 5-minute Apgar <7, were compared based on type of neuraxial anesthetic.

RESULTS:

A total of 4100 patients were included in the analysis, 1696 (41.4%) received spinal anesthesia 1848 (45.1%) received epidural anesthesia and 556 (13.5%) received a combined spinal-epidural (CSE). Antepartum and intrapartum characteristics significantly differed between the groups ( p≤0.02). After adjusted analysis, spinal anesthesia was associated with reduced odds of NICU admission, compared with epidural or CSE (OR; 95% CI: 0.79; 0.63–0.98, 0.71; 0.53–0.94, respectively). Spinal anesthesia was also associated with lower odds of a 5-minute Apgar <7 compared with epidural anesthesia (OR 0.59; 95% CI; 0.43–0.83). We found no association between type of anesthesia and arterial cord pH ≤7.2. In stratiifed analysis by gestational age, no association between the type of neuraxial anesthesia and neonatal outcomes was noted among term infants, but associations persisted in preterm infants.

CONCLUSIONS:

Among women with preeclampsia undergoing cesarean delivery, spinal anesthesia may be associated with reduced short-term neonatal morbidity in preterm infants, compared with epidural or CSE.
Use of acidified versus non-acidified liquid human milk fortifier in very low birth weight infants: A retrospective comparison of clinical outcomes
Authors: Darrow C.J. , Bai-Tong S.S. , Kang E.M. , Thompson C.L. , Walsh M.C.
Published: November 2019

BACKGROUND:

Use of human milk is recommended for low birth weight (VLBW) infants, but must be safety fortified with sterile liquid fortifiers to be nutritionally sufficient. Due to clinical concern for a high incidence of metabolic acidosis among VLBW infants fed human milk fortified with acidified liquid human milk fortifier (ALHMF), we aimed to retrospectively compare the outcomes of infants fed ALHMF to those fortified with non-acidified liquid HMF (NLHMF).

METHODS:

Medical records of VLBW neonates admitted to our institution’s neonatal intensive care unit from July 1st, 2013 to June 30th, 2014 were reviewed. 129 patients were included in the study, 61 of which received ALHMF and 68 received NLHMF. Metabolic, nutritional and clinical outcomes, including growth, were compared between the two cohorts.

RESULTS:

Of the infants who received ALHMF, 70.5% developed metabolic acidosis compared to only 11.8% in the NLHMF group ( p < 0.001). In addition, infants who received NLHMF had a 10% greater growth velocity during the period of fortification ( p = 0.01). During the full course of hospitalization, no difference in growth velocity was seen between the groups and greater length gains were found in the ALHMF group.

CONCLUSIONS:

The use of human milk fortified with ALHMF was associated with an increased incidence of metabolic acidosis and poorer growth during the period of fortification when compared to NLHMF-fortified feedings. These growth effects were not apparent when the duration of hospitalization was considered, suggesting a need for further study to better characterize the advantages and disadvantages of each fortifier.
Low caloric intake and high fluid intake during the first week of life are associated with the severity of bronchopulmonary dysplasia in extremely low birth weight infants
Authors: Al-Jebawi Y. , Agarwal N. , Groh Wargo S. , Shekhawat P. , Mhanna M.J.
Published: November 2019

OBJECTIVE:

To study whether there is an association between nutritional intake during the first week of life and severity of bronchopulmonary dysplasia (BPD) in extremely low birth weight (ELBW) infants.

METHODS:

In a retrospective cohort study, medical records of all ELBW infants admitted to our Neonatal Intensive Care Unit (2010–2017) were reviewed for infants’ demographics, clinical characteristics, nutritional intake during their first week of life, and BPD risk factors.

RESULTS:

During the study period 226 infants were identified of whom 67% (151/226) had moderate-severe BPD and the rest served as controls. Overall infants with moderate-severe BPD were younger, smaller, and spent more time on mechanical ventilation than their controls [(mean±standard deviation) 24.7±1.7 vs. 26.8±2.0 weeks gestational age ( p < 0.001); 678±154 vs. 837±129 grams ( p < 0.001); and 37.9±23.6 vs. 13.7±15.3 days ( p < 0.001) respectively]. During the first week of life, the average caloric, carbohydrate, protein and lipid intakes were significantly lower, and the average fluid intake was significantly higher in the moderate-severe BPD than the control group. After adjustment for confounders, fluid intake, and days on mechanical ventilation were significantly associated with moderate-severe BPD with an odds ratio [OR (95% confidence interval)] of 1.03 (1.01–1.04), and 1.05 (1.03–1.07) respectively. Daily caloric intake was associated with an increased risk for moderate-severe BPD [OR: 0.94 (0.91–0.97)].

CONCLUSION:

Low caloric intake, and high fluid intake during the first week of life are associated with the severity of BPD in ELBW infants.
Brief report: Metabolic acidosis in newborn infants following maternal use of acetazolamide during pregnancy
Authors: Ibrahim A. , Hussain N.
Published: November 2019

The information regarding fetal effects of acetazolamide use during pregnancy and lactation is sparse. We report the clinical and pharmacodynamic characteristics of maternal acetazolamide use and the timing of its effects on acid-base balance in three cases who presented with metabolic acidosis in the newborn period. We found that the infants’ clinical status soon after birth was inconsistently correlated with maternal drug dose and concentrations of medication in maternal serum. However, there was low transfer of the drug in breast milk and its use did not affect clinical symptomatology. We also present a review of literature on this subject to help consolidate our current knowledge on this topic.
Multi-attribute decision making based on novel generalized parametric exponential intuitionistic fuzzy divergence measure
Authors: Parkash Om , Kumar Rakesh
Published: November 2019

In this work, the main theme is to investigate a novel generalized parametric exponential intuitionistic fuzzy divergence measure along with the study of its detailed properties for its authenticity. The applications of this newly developed generalized intuitionistic fuzzy divergence measure have been provided to multi-attribute decision making (MADM). Numerical verification has been illustrated to demonstrate the proposed method for solving multi-attribute decision making problem under fuzzy environment.
Recommend interesting items: How can social curiosity help?
Authors: Wu Qiong , Liu Siyuan , Miao Chunyan
Published: November 2019

The ultimate goal of recommender systems is to suggest appealing items that users are interested in. Traditional recommender systems are built based on a general consensus that users’ preferences reflect their underlying interests. Therefore, various collaborative filtering techniques have been proposed to discover items that best match users’ preferences through estimating ratings for items accurately. However, determining the interestingness of items based on user preferences alone is not sufficient. In human psychology, researchers have found an important intrinsic motivation, i.e., curiosity, for seeking interestingness in social context. Instead of focusing on users’ preferences, curiosity highlights the impact of the unknown and unexpectedness on a person’s feeling of interestingness. In light of this, we propose a novel recommendation model which recommends items by taking consideration of the target users’ curiosity in addition to their personal preferences. To model user curiosity, we adopt a psychologically inspired approach and transpose Berlyne’s theory of curiosity into a computational process. Three key curiosity-stimulating factors, including surprise, uncertainty and conflict, are modelled to estimate user’s curiosity for each item. The proposed recommendation model is evaluated with two large-scale real world datasets and the experimental results highlight that the consideration of social curiosity significantly improves recommendation precision, coverage and diversity.
TEORI KEADILAN (THEORY OF JUSTICE) Kajian dalam Perspektif Filsafat Hukum Islam Dan Barat
Authors: P Fuji Rahmadi
Published: November 2019

There is not any emphasis on the value of justice greater than this matter (that God sent His apostles and sent down His Book) to bring about justice. In the name of justice the books were revealed and the Apostles were sent. Because of this justice, the life of heaven and earth is also upheld. The evolution of the philosophy of law, which is inherent in the whole philosophy evolution, revolves around the certain problems that arise repeatedly. Among these problems, the most frequent discourse is the issue of justice in relation to the law. It happens because laws or regulations should have been fair, but in fact they often don't.

Keywords: justice, philosophy, law, perspective, West, Islam

Abstrak: Tiada penekanan akan nilai keadilan yang lebih besar dari pada perkara ini (bahwa Allah mengutus para rasul-Nya dan menurunkan Kitab-Nya) untuk mewujudkan keadilan. Maka dengan atas nama keadilan kitab-kitab diturunkan dan para Rasul diutus. Dengan keadilan ini pula tegaklah kehidupan langit dan bumi. Evolusi filsafat hukum, yang melekat dalam evolusi filsafat secara keseluruhan, berputar di sekitar problema tertentu yang muncul berulang-ulang. Di antara problema ini, yang paling sering menjadi diskursus adalah tentang persoalan keadilan dalam kaitannya dengan hukum. Hal ini dikarenakan hukum atau aturan perundangan harusnya adil, tapi nyatanya seringkali tidak.

Kata Kunci: keadilan, filsafat, hukum, perspektif, Barat, Islam
Pisolithus arrhizus Ekstraktı Kullanılarak Sentezlenen Titanyum Nanopartikülünün Antimikrobiyal Etkisi
Authors: YUVALI ÇELİK Gökçen , ONBAŞLI Dilşad , ÖZBAHAR Özge , ÖÇSOY İsmail
Published: November 2019

Pisolithus arrhizus (Scop.) Rauschert (Basidiomycetes) türü okaliptüs ve çam ağaçlarının birçok türünü çevreleyen kökleri toprakta bulunan bir ektomikorizal mantardır. Bu araştırmada Pisolithus arrhizus etanol ekstraktı kullanılarak hazırlanan Titanyum (TiO2) nanopartikülünün (NP) farklı patojen mikroorganizmalar üzerinde inhibitörik etkisinin tespit edilmesi amaçlanmıştır. Çalışmada hydrothermal yöntem kullanılarak sentezlenen mantar ekstreli TiO2 NP, UV-Vis Spektrometre (UV-vis) ve taramalı elektron mikroskop (SEM) ile karakterize edilmiştir. Hazırlanan ve karakterize edilen bu NP’lerin, disk difüzyon yöntemi kullanılarak Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Candida albicans ve Streptococcus mutans test patojenleri üzerinde antimikrobiyal aktivitesi araştırılmıştır. Mantar ekstreli TiO2 NP’lerin patojenler üzerinde zayıf bir inhibisyon etkisine sahip oldukları (7.5-9.3 mm), maksimum inhibisyonu (9.3 mm) S. mutans'a karşı gösterdiği buna karşın C. albicans’a karşı antifungal etkiye sahip olmadıkları tespit edilmiştir.