bluuebunny/crossref_metadata_2025 huggingface dataset:
Deciphering Alzheimer’s Disease Pathogenic Pathway: Role of Chronic Brain Hypoperfusion on p-Tau and mTOR
Authors: de la Torre Jack C.
Published: January 2021

This review examines new biomolecular findings that lend support to the hemodynamic role played by chronic brain hypoperfusion (CBH) in driving a pathway to Alzheimer’s disease (AD). CBH is a common clinical feature of AD and the current topic of intense investigation in AD models. CBH is also the basis for the vascular hypothesis of AD which we originally proposed in 1993. New biomolecular findings reveal the interplay of CBH in increasing tau phosphorylation (p-Tau) in the hippocampus and cortex of AD mice, damaging fast axonal transport, increasing signaling of mammalian target of rapamycin (mTOR), impairing learning-memory function, and promoting the formation of neurofibrillary tangles, a neuropathologic hallmark of AD. These pathologic elements have been singularly linked with neurodegeneration and AD but their abnormal, collective participation during brain aging have not been fully examined. The format for this review will provide a consolidated analysis of each pathologic phase contributing to cognitive decline and AD onset, summarized in nine chronological steps. These steps galvanize each factor’s active participation and contribution in constructing a biomolecular pathway to AD onset generated by CBH.
Broader Insights into Understanding Tumor Necrosis Factor and Neurodegenerative Disease Pathogenesis Infer New Therapeutic Approaches
Authors: Clark I.A. , Vissel B.
Published: January 2021

Proinflammatory cytokines such as tumor necrosis factor (TNF), with its now appreciated key roles in neurophysiology as well as neuropathophysiology, are sufficiently well-documented to be useful tools for enquiry into the natural history of neurodegenerative diseases. We review the broader literature on TNF to rationalize why abruptly-acquired neurodegenerative states do not exhibit the remorseless clinical progression seen in those states with gradual onsets. We propose that the three typically non-worsening neurodegenerative syndromes, post-stroke, post-traumatic brain injury (TBI), and post cardiac arrest, usually become and remain static because of excess cerebral TNF induced by the initial dramatic peak keeping microglia chronically activated through an autocrine loop of microglial activation through excess cerebral TNF. The existence of this autocrine loop rationalizes post-damage repair with perispinal etanercept and proposes a treatment for cerebral aspects of COVID-19 chronicity. Another insufficiently considered aspect of cerebral proinflammatory cytokines is the fitness of the endogenous cerebral anti-TNF system provided by norepinephrine (NE), generated and distributed throughout the brain from the locus coeruleus (LC). We propose that an intact LC, and therefore an intact NE-mediated endogenous anti-cerebral TNF system, plus the DAMP (damage or danger-associated molecular pattern) input having diminished, is what allows post-stroke, post-TBI, and post cardiac arrest patients a strong long-term survival advantage over Alzheimer’s disease and Parkinson’s disease sufferers. In contrast, Alzheimer’s disease and Parkinson’s disease patients remorselessly worsen, being handicapped by sustained, accumulating, DAMP and PAMP (pathogen-associated molecular patterns) input, as well as loss of the LC-origin, NE-mediated, endogenous anti-cerebral TNF system. Adrenergic receptor agonists may counter this.
A Retrospective Study on the Benefits of Combined Citicoline, Memantine, and Acetylcholinesterase Inhibitor Treatments in Older Patients Affected with Alzheimer’s Disease
Authors: Castagna Alberto , Fabbo Andrea , Manzo Ciro , Lacava Roberto , Ruberto Carmen , Ruotolo Giovanni
Published: January 2021

Background:

Background: Citicoline has been proven to have beneficial effects in patients with cognitive impairment. In previous studies, combined treatment with memantine and acetylcholinesterase inhibitors (AChEIs) maintained cognitive function in patients with Alzheimer’s disease (AD) better than memantine or AChEIs alone.

Objective:

To evaluate the effectiveness and safety of a combination therapy of oral citicoline, memantine, and an AChEI in AD when compared with memantine and an AChEI without citicoline.

Methods:

This was a retrospective multi-centric case-control study, conducted in Italian Centers for Cognitive Impairment and Dementia. Overall, 170 patients were recruited (34.11%of men, mean age 76,81±4.93 years): 48.8%treated with memantine and donepezil; 48.2%with memantine and rivastigmine; 2.9%with memantine and galantamine. 89 patients (control-group) were treated with memantine and an AChEI, whereas 81 patients (case-group) were treated with oral citicoline 1000 mg/day added to memantine and an AChEI given orally. Cognitive functions, activities of daily living, instrumental activities of daily living, comorbidities, mood and behavioral disturbances were assessed at baseline, month 6, and month 12.

Results:

In the case group, MMSE score had a statistically significant increasing trend between T0 and T2 (14.88±2.95 versus 15.09±3.00; p = 0.040), whereas in the control group, MMSE score showed a statistically significant decrease trend (14.37±2.63 versus 14.03±2.92 p = 0.024).

Conclusion:

In older patients with AD, a triple therapy with citicoline, memantine, and AChEI was more effective than memantine and AChEI without citicoline in maintaining the MMSE total score after 12 months.
Setting Up a Cognitive Training Service for Egyptian Older Adults
Authors: Hassanin Hany I. , Tawfik Heba M. , Zygouris Stelios , Tsatali Marianna , Sweed Hala S. , Tsolaki Magda
Published: January 2021

Background:

With greying of nations, dementia becomes a public health priority. The rising dementia prevalence escalates both health care expenses and burden, placing the entire healthcare system and caregivers under huge stress. Cognition-oriented interventions have been shown to enhance the overall cognitive performance among healthy and cognitively impaired older adults.

Objective:

This article is assumed to be a steppingstone for the introduction and establishment of cognition- oriented interventions in Egypt. In addition, it aims to offer provisional guidance for health care providers in Arab speaking countries in a stepwise approach in order to establish cognition-oriented intervention services and help them to evaluate and monitor their efficacy.

Methods:

Aconsortium of Egyptian and Greek specialists developed a protocol for the operations of the Ain Shams Cognitive Training Lab and the provision of cognition-oriented interventions. This protocol is based on a previous successful protocol that has been implemented in Greece for more than 10 years and is co-designed to fit the needs of older adults in Arabic speaking countries.

Results:

The types of services offered, their objectives, recruitment of participants, delivery of interventions, measurement of outcomes and privacy policy are all outlined in the policy.

Conclusion:

Establishing the appropriate framework in which cognitive training strategies can be adapted and implemented in Arabic population, constitutes an inevitable achievement in healthy ageing and can be also assumed as a dementia prevention strategy. Moreover, setting up the first cognitive laboratory in Egypt older adults, can be a model of good practice across the Arabic countries.
STRUCTURAL CHANGES OF THE ORAL MUCOSA IN RATS WITH INSULIN RESISTANCE, IODINE DEFICIENCY AND UNDER CONDITIONS OF THEIR COMBINATION
Authors: Huranych S.P. , Voronych-Semchenko N.M. , Bagrii M.M.
Published: January 2021

Relevance. The relationship between endocrinopathies and the condition of the oral cavity is associated with disorders of metabolism, hemodynamics, immunological and neuroregulatory changes. Since the first line of contact with the environment of the oral cavity is the mucous membrane, changes in its properties adversely affect the functional state of other periodontal tissues.

Objective: to examine the structural changes of the oral mucosa in rats with combined endocrinopathy.

Materials and methods. The studies were carried on 120 rats, which were divided into three experimental (animals with iodine deficiency – ID, insulin resistance – IR, IR on the background of ID) and a control group of animals. Histological examination of the oral mucosa, computer morphometry, and densitometry of objects was performed.

Results. In rats with ID, the epithelium of the mucous membrane was characterized by the development of acanthosis, expansion of the granular layer, enhanced keratin formation. The development of IR caused hyperplastic changes in the epithelium with the formation of unexpressed cords of acanthosis, epithelial basal hypercellular infiltration, which was confirmed by morphometric data. Under conditions of combined endocrinopathy, more pronounced changes in the histological structure of oral mucosa were observed. In particular, the development of mucosal edema in connective tissue, with predominantly macrophage hypercellularity at the periphery, was noted. Densitometric examination of the samples indicated a decrease in the optical density of connective tissue. At the same time, hyperplastic changes in most layers of the epithelium and pronounced changes in the vascular wall were observed.

Conclusions. Combined endocrinopathy leads to pronounced changes of the oral mucosa, which can lead to disruption of the structure of periodontal tissues and the entire tooth-alveolar complex.
EL DESAFÍO DE LA DOCENCIA: BIOGRAFÍA, ACTIVISMO Y REDES CURRICULARES EN LAS ESCUELAS
Authors: De Garay Hernandez Jimena , Nascimento Letícia Carolina Pereira do , Caetano Marcio
Published: January 2021

Las biografías son fragmentos que nos presentan la vida de diversos puntos. Estas narran experiencias, tramas y construcciones de identidades. Aquí nos interesan los modos y las “verdades” sobre la sexualidad y como ellas sociabilizaron experiencias en las escuelas. Con tres docentes que actúan en escuelas de ciudades del interior de los estados de Rio de Janeiro e Rio Grande do Sul, presentamos los diferentes manejos con los cuales la sexualidad funcionó, cumpliendo una función de saber y poder. A través de las narrativas fue posible observar cómo los sujetos construyeron sus cadenas de significados y estructuraron sus performatividades. Estas operaron mediadas con la responsabilidad con el futuro de sus estudiantes, la imagen de buena/o profesional y la homofobia.
Editorial
Authors: Lage Allene
Published: January 2021

Editorial
THE EFFECT OF FREE CASH FLOW AND PROFITABILITY ON DIVIDEND PAYOUT RATIO (CASE OF LQ-45 INDEXED FIRMS IN INDONESIA STOCK EXCHANGE FOR PERIOD 2011-2018)
Authors: Lohonauman Hans , Budiarso Novi Swandari
Published: January 2021

This study aims to determine the effect of free cash flow and profitability on dividend payout ratio at LQ45 Index Companies Listed on the Indonesian Stock Exchange 2011-2018. The population used in this study is the LQ45 index company listed on the Indonesian Stock Exchange in 2011-2018. The sampling method was purposive sampling according to predetermined criteria. The number of samples collected was 7 companies. The research data is secondary data obtained from the Indonesian Stock Exchange (IDX) in 2011-2018. The data that has been collected is analyzed using data analysis that first tested with classical assumptions before testing the hypothesis. Hypothesis testing in this study uses multiple linear regression analysis with the t test, f test, and the coefficient of determination. The result of this study indicates that free cash flow does not affect the level of dividend payout ratio. While profitability has a significant effect on dividend payout ratio. This shows that profitability affect the level of dividend payout ratio.
ADMINISTRATIVE MEASURES FOR PREVENTION OF CORRUPTION IN THE BODIES OF THE NATIONAL POLICE
Authors:   Lviv State University of Internal Affairs, Hurkovskyi Marian
Published: January 2021

The administrative measures for preventing corruption in the system of the National Police are investigated. The category �legal measures� in the context of modern scientific thought is considered in the theoretical aspect. The normative and legal framework for preventing corruption in the National Police is analyzed. During the analysis, the need to develop the institution of administrative measures for preventing corruption as the most widely used legal means in the system of preventing corruption in terms of international instruments in this field is substantiated. The significance of legal prohibitions and legal incentives in the system of administrative measures is revealed. Administrative measures for preventing corruption in the National Police bodies form a legal regime that is special in relation to the general administrative and legal regime of the public service and can be characterized as an ordinary, permanent, mostly prohibitive administrative and legal regime for preventing corruption in the National Police. The specificity of the administrative and legal regime for the prevention of corruption is defined by the formation of general provisions addressed to all public officials and special rules addressed exclusively to the police. The effectiveness of the administrative and legal regime is determined by a number of factors due to anti-corruption standards. The importance of anti-corruption standards for administrative measures of preventing corruption in the bodies, services and units of the National Police and the need of their development depending on the specifics of the unit are determined. Conceptual tasks of improving administrative measures for preventing corruption in the National Police are formulated.
APPLICATION OF PROFILING TO COMBAT CYBER CRIME
Authors:   Lviv State University of Internal Affairs, Zachek Oleh , Dmytryk Yurii ,   Lviv State University of Internal Affairs
Published: January 2021

The article is devoted to the study of current problems of application of advanced methods of profiling in the process of combating cybercrime by units of the National Police. The fight against cybercrime has recently become increasingly important, as there has been a significant increase in the number of cybercrimes. Ukrainian cyber police units must use the most modern methods to combat such crimes. One such method is profiling, which is an important tool for investigating crimes, including information crimes. It allows us to classify cybercriminals, understand their habits and technologies and aims to identify the perpetrator. Due attention is not paid to psychological aspects quite often in operational and investigative activities, resulting in the problem of diagnosis and assessment of the offender. Profiling allows to solve this problem and to increase efficiency of professional activity of divisions of cyber police of National police of Ukraine. But profiling is not used practically in the activities of these units in this time, although the use of profiling in the investigation of cybercrime is quite common in the world's leading countries. Therefore, we aimed to consider the problems of application of advanced profiling techniques in the process of combating cybercrime in the activities of cyber police units, as well as to provide suggestions for improving the current legislation. None of the existing legal documents of our state provides for the use of profiling in the activities of cyber police. Underestimation of capabilities of profiling in cyber police units of the National Police of Ukraine requires rethinking currently. Profiling technologies can be successfully implemented in the activities of operational units of the National Police, including cyber police units, due to it combat crime will be more effectively. It is advisable to add to the existing search measures at the legislative level such a measure as "operational profiling" to this end, that will allow to widely use its capabilities.
KONSENTRASI PUPUK ORGANIK CAIR (POC) NASA DAN TEKNIK APLIKASI TERHADAP HASIL TANAMAN MENTIMUN (Cucumis sativus L.)
Authors: Anggraeny Putri Cahya , Astiningrum Murti , Perdana Adhi Surya
Published: January 2021

Budidaya tanaman mentimun (Cucumis sativus L.) di wilayah Kecamatan Bandongan, Kabupaten Magelang masih terbatas dan belum dibudidayakan secara intensif karena petani belum menggunakan pupuk organik. Pupuk organik dapat diberikan dalam bentuk cair dan perlu diperhatikan konsentrasi serta cara aplikasi yang tepat. Penelitian ini bertujuan untuk mengetahui konsentrasi pupuk organik cair dan teknik aplikasi yang memberikan hasil tertinggi pada tanaman mentimun serta menganalisis interaksi antara konsentrasi dan teknik aplikasi pupuk organik cair terhadap hasil tanaman mentimun. Penelitian dilaksanakan pada bulan Juni hingga Agustus 2019 di Desa Banyuwangi, Kecamatan Bandongan, Kabupaten Magelang, dengan ketinggian tempat 382 m dpl, jenis tanah Latosol dan pH 6,6. Penelitian dilakukan menggunakan percobaan faktorial (4 x 2) yang disusun dalam rancangan acak kelompok lengkap dengan tiga blok. Faktor pertama konsentrasi pupuk organik cair : 0, 2, 4, dan 6 ml/L. Faktor kedua teknik aplikasi pupuk : disemprot dan dikocor. Data yang diperoleh dianalisis dengan sidik ragam dan dilanjutkan dengan uji orthogonal polynomial dan uji BNT untuk faktor pertama dan uji – t untuk faktor kedua. Hasil analisis menunjukkan bahwa konsentrasi pupuk organik cair 2 ml/L memberikan hasil tertinggi pada parameter panjang tanaman, berat per buah, panjang buah dan volume buah. Perlakuan teknik aplikasi pupuk organik cair dan interaksi antara konsentrasi dan teknik aplikasi pupuk organik cair memberikan hasil yang berbeda tidak nyata pada semua parameter.
U.S. economy and social structure before the change of eras
Authors: Grigoryev L. M. , Grigoryeva N. L.
Published: January 2021

Dramas of a unique pandemic of COVID-19, an unparalleled sharp recession and critically important presidential elections have put the difficult choices for the American society in 2020. Socio-economic development of the U.S. in XXI century has come through the series of crises, which had major impacts on the global development. The country has retained the leadership in the developed world by general economic might, innovations and dynamics of upturns. In the last three decades the demographics of the U.S. population have experienced the substantial changes, notably the number of citizens of Asian origin and Hispanic group have increased. The latter has surpassed the Afro-American group by a number of families and by an average income per family. Overall growth of income in the country has not eliminated large income disparities among social strata. Statistics of tax declarations indicate the inequality by social groups and by race. These disparities have probably played an important role in 2020 recession and pandemic development. As far as electoral behavior is concerned, the inequality factor is even more visible.
Finitude e Bioética do Fim da Vida
Authors: Schramm Fermin Roland
Published: January 2021

A adjetivação (“finito”) pode referir-se a bens, como na expressão “recursos finitos” - que se tornou uma palavra-chave na bioética sanitária - ou a seres vivos, que podem ser humanos ou não. Na expressão “finitude humana”, o substantivo “finitude” se refere a uma característica universal da condição existencial humana, que pode ser indicada também pelo termo vulnerabilidade (do latim vulnus “ferido”), ou seja, o fato de todo ser humano poder ser “ferido”, adoecer e sofrer. Portanto, por estar exposto aos riscos da vida, em sua existência, o indivíduo pode passar da potencialidade – representada pela “vulnerabilidade” - ao ato - e tornar-se “vulnerado”.
Alteraciones en las personas que realizan deporte de manera eventual sin previo calentamiento en la carrera atlética binacional 14 k Ipiales " Tulcán
Authors: Salgado Jimenez Ruth Elizabeth , Nasamues Morillo Maira Gabriela
Published: January 2021

Las alteraciones deportivas son lesiones que ocurren durante la práctica del ejercicio físico; algunas ocurren accidentalmente otras pueden ser el resultado de malas prácticas de entrenamiento. Por tal razón antes de realizar cualquier actividad el cuerpo debe entrar en calor a través del calentamiento que es un conjunto de actividades realizadas en la parte inicial de una sesión física, de forma que el organismo pase de un estado de reposo a un estado de actividad y prepara al organismo para posteriores esfuerzos, evitando posibles lesiones en el organismo, permitiendo la adaptación del corazón, la circulación sanguínea, el aparato respiratorio, así como del trabajo a nivel tendinoso y muscular. Este estudio fue realizado en atletas temporales de diversas edades para determinar las alteraciones en las personas que realizan deporte de manera eventual sin previo calentamiento en la carrera atlética binacional 14 K Ipiales (Colombia) " Tulcán (Ecuador), el cual se desarrolló a través de un estudio de tipo descriptivo, exploratorio y bibliográfico, que permitió analizar e intervenir para dar una propuesta de solución a la problemática encontrada. Los datos obtenidos gracias a la aplicación de las encuestas a los participantes de la carrera atlética binacional permitieron evidenciar algunas alteraciones o lesiones en el organismo por no realizar calentamiento antes de un esfuerzo físico de gran intensidad, en el cual el organismo humano no se ha sometido a un precalentamiento así como a la preparación psicológica de la prueba a la que se sometieran participantes menores de 12 años hasta mayores de 50 años, trayendo consigo la potencial afectación que causa dolor, trastornos e incluso afectaciones de larga duración y de consecuencias impredecibles. Se concluye que en atletas ocasionales, cuando no se transita, antes de iniciar el evento deportivo, por el precalentamiento y la preparación psicológica, se presentan frecuentemente alteraciones de impredecible magnitud que ponen en riesgo su salud.
The Environmental Impact of Palm Oil: Introduction for Students of Tasmania University, Australia
Authors: Chalil Diana , Barus Riantri , Nababan Ester Sorta Mauli , Sembiring Pramio Garson , Hasanuddin  , Sofyan Rudy , Tulus
Published: January 2021

Palm oil is one of the most demanded commodities globally, which has led to a significant increase in its production and raised issues regarding its environmental impact. However, many of these issues are not based on substantial evidence. To provide a proportional picture on the oil palm industry, Universitas Sumatera Utara (USU), the University of Tasmania (UTAS) and the Association of Indonesian Palm Oil Entrepreneurs (GAPKI) have collaborated to carry out this program. The program was conducted for seven days through classroom lectures and field trip activities, involving 14 students and two supervisors from UTAS and four USU students. Pre and post-tests were conducted to evaluate the impact of the program.  The results showed changes in participants' knowledge and perception regarding the environmental, social, and economic effects of the oil palm industry. Therefore, this program could be considered an effective counter to misleading Indonesian palm oil industry issues.
Community Empowerment towards Healthy Living through The Implementation of Healthy Living Community Movements (GERMAS)
Authors: Siregar Fazidah A
Published: January 2021

Indonesia is currently facing a triple burden of disease where the incidence of non-communicable diseases is increasing. The condition is related to lifestyle include lack of physical activity, an unhealthy and unbalanced diet, and unhealthy lifestyle as smoking and alcohol consumption. To educate the community to implement healthy living, GERMAS is being promoted, emphasizing promotive and preventive efforts. The purpose of these activities was to educate and mobilize the community to implement healthy living by implementing GERMAS that focuses on physical activities, consuming vegetables and fruit, and checking health regularly. From the health status monitoring, 15.6% of participants were in the systolic prehypertension stage, and 34.4% were in the systolic hypertension stage, 19.0% with high cholesterol levels, 43.8% with high uric acid levels and 21.9% with high blood sugar levels. This activity was continued by giving education about balanced and healthy food, routine physical activities during three months and the use of their yards for planting vegetables and fruit and motivating the communities for consuming the healthy food daily. After three months,  the health condition improved in which the number of participants with systolic hypertension and high blood sugar levels decreased to 30% and 12.5%, respectively. It was concluded that the implementation of healthy life society movement daily could reduce the biological risk factors leading to the reduction of non-communicable disease incidence.
Digestibility of a diet with hydroponic maize (Zea mays L.) green fodder and its effect on lamb growth
Authors: Cantón-Castillo Javier J. , Alcaraz-Romero Rosendo A. , Chiquini-Medina Ricardo A. , Maya-Martínez A.
Published: January 2021

Objective: To determine the apparent digestibility (AD) of diets with hydroponic green corn forage (HGCF) and to evaluate its effect on the dry matter (DM) intake and daily weight gain (DWG) of lambs.
Design/methodology/approach: Two experiments using four levels of inclusion (0, 20, 40, 60% DM) of HGCF in the diet were carried out. For determine the AD of diet 16 sheep were used and for the growth evaluation 20 male lambs. A completely randomized design in both studies was used.
Results: A higher AD of DM and crude protein in diets with 40% and 60% of HGCF was observed (P<0.05; P<0.01). Lambs from 0 and 20% HGCF treatment had a higher DWG. A lower DM intake in 60% HGCF diet was registered (P<0.05).
Limitations on study/implications: Currently there are various methods to supplement sheep during dry season, however, few are fully adapted to the needs of farmers. Hydroponic green corn forage is a valuable alternative for fast and constant production of forage with high nutritional value for sheep.
Findings/conclusions: Hydroponic green corn forage has high digestibility, therefore, it can be used as an excellent source of forage in the diet of lambs, obtaining appropriate weight gains with rations that include up to 40% in the diet to replace commercial food.
Groundwater Contamination due to the Use of Agrochemicals in Sugar Cane Agroecosystems
Authors: Soto Estrada Alejandra , Landeros Sánchez Cesáreo , Hernández Pérez Juan Manuel
Published: January 2021

Objective: Assess the risk of groundwater contamination due to the application of pesticides and the amount of nitrogen leached in agroecosystems with sugar cane in the area of influence of sugar mills, La Gloria y El Modelo, Veracruz, Mexico.
Methodology: The presence of pesticides at 30 groundwater sampling points was determined by using the Mexican regulation N0M-041-SSA1-1993 and the EPA 608 and EPA 608.1 methods described by the Environmental Protection Agency (EPA). Nitrogen (N) loss by leaching was assessed evaluating nine treatments by combining two factors: dose (250, 200 and 150 kg ha-1 of N) and application fractionated doses (2, 3 y 4).
Results: Pesticides such as ?-hexachlorocyclohexane (?-HCH), heptachlor heptachloroepoxide, ?-endosulfan, ? endosulfan, sulfate-endosulfan, aldrin, dieldrin and dichlorodiphenyldichloroethylene (4.4’DDE) were found in groundwater of deep wells of agroecosystems with sugarcane. Application of low doses of N resulted in lower losses of N due to leaching. A dose of 150 kg ha-1 of N, applied in two, three, and four fractions, generated N losses between 15.40 to 18.18 kg ha-1, which means a loss of up to 12.1%.
Conclusions: Groundwater contamination by agrochemicals, such as pesticides is indubitable; so, reducing such contamination should be a priority for crop growers involved. Also, nitrogen, soil and water management and conservation practices must be done. This will result in a less negative impact to the environment and public health. Water and nitrogen fertilizers management at plot level are to be improved in order to increase water irrigation and nitrogen efficiency in agricultural areas.
Prediction of Milk Production per Cow Lactation in the Mexican Tropics
Authors: Herrera-Sotero Mónica Yazmín , Vinay-Vadillo Julio César , León-García Elizabeth , Enríquez-Quiroz Javier Francisco , Piña-Cárdenas Benjamín Alfredo , Alvarez-Vazquez Perpetuo
Published: January 2021

Objective: To evaluate non-linear and linear mathematical models used to estimate milk production per lactation, at different frequencies of milk weighing from records of Holstein (Ho), Brown Swiss (BS) cows and their crosses with Zebu (Z).
Design/Methodology/Approach: The models evaluated were: Wood, Wilmink and Linear Interpolation. Daily records of milk production from 471 lactations of 72 cows were used; 1,884 records were created with frequencies of weekly, biweekly and monthly milk production. The following were included in the statistical model: the genotype (Ho X Z andSP X Z), birth season (rainy and dry), and number of lactation (1 and 2) with double and triple interactions. The statistical analyses were performed with GLM from MINITAB v17. The means were compared with Tukey’s test.
Results: No differences were found (P?0.05) between the models for the average milk production per lactation in kg, obtained from daily measurements or estimated from weekly, biweekly and monthly data, although for the factors of birth season, number of lactation, and genotype they showed differences (P ? 0.05) in milk production per lactation.
Study Limitations/Implications: Daily records of milk production are necessary to obtain production per lactation; the models applied predict milk production in a similar way in different frequencies of weighing in Holstein, Brown Swiss cows and their crosses with Zebu.
Findings/Conclusions: The models used allow predicting the milk production per cow in a similar way in different frequencies of weighing.
Critical Nitrogen and Nutritive Index in Cultivars of Cenchrus purpureus (Schumach) Morrone
Authors: Vinay-Vadillo Julio Cesar , Enriquez-Quiroz Javier Francisco , Montero-Lagunes Maribel , Herrera-Sotero Mónica Yazmín , Mendoza-Pedroza Sergio Iban , Bolaños-Aguilar Eduardo Daniel
Published: January 2021

Objective: To determine and compare the parameters of the nitrogen curve and the nutritive nitrogen index of cultivars of Cenchrus purpureus with and without nitrogenous fertilization.Design/Methodology/Approach: Five cultivars of C. purpureus with or without fertilization were evaluated, and the dose was 141N-43P-20K. The grass was harvested every 21 d with production of dry matter (DM) and nitrogen (N). Growth rates and Critical Nitrogen (Nc) were obtained. The negative power equation with its parameters Nc and the Nitrogen Decrease Coefficient (Cd) were used. The Nutritive Nitrogen Index (NNI) was obtained with the Nc parameter of each curve, divided by the N content of the cultivar in each sampling. The data were analyzed with a completely randomized design in a factorial arrangement of five (cultivars) and two levels of fertilization.
Results: Nc of 2.6 and a Cd of 0.65 fertilized, and 1.14 of Nc and 0.68 of Cd without fertilization, and in turn all of them supplemented the amount of N for their growth from soil. The NNI was 0.8 for the fertilized cultivars, with classification of excess and sufficient for the first 56 d.
Study Limitations/Implications: Variables to determine the availability of water and the balance of soil-plant N could further expand the knowledge of these tools.
Findings/Conclusions: Parameters obtained such as Nc and NNI help to determine nutritional status of the fodders.
Zikir Nabi Yunus A.S sebagai Pendidikan Tauhid dalam Mengatasi Kecemasan di Masa Covid-19
Authors: Aminah Siti
Published: January 2021

The Covid 19 pandemic causes a variety of reactions among these is anxiety. Anxiety results from social isolation, lack of interaction, limited physical movements and changing stress. Anxiety can certainly be overcome, one by applying tauhid's education of dzmikees. Zikir can serve as a restraint because to think that a servant always remembers god, his prohibitions and commands, so as to make one more cautious in his actions and behavior. One of the applicable Zikir is the Nabi Yunus A. S, with this vessel he was saved by god almighty from the belly of the big fish. Zikir the Nabi Yunus A.S is a prayer uttered by the Nabi Yunus A.S when drawn to god, of a quality he ought not to be patient with. The study aims to introduce and remind that Zikir the Nabi Yunus A.S tauhid's education can be one way of coping with the anxieties of Covid 19. The study is a fieldwork with a qualitative approach. Research has found that; First, the dismay felt by society at this crucial time was still in the normal category; Second, acting, acting, and being patient are helpful in coping with and coping with anxiety during the Covid pandemic 19.

Pandemi Covid-19 menimbulkan berbagai macam reaksi salah satunya ialah kecemasan. Kecemasan diakibatkan dari isolasi sosial, kurangnya interaksi, gerakan fisik yang terbatas dan stressor yang berubah. Kecemasan tentu dapat diatasi, salah satunya dengan menerapkan pendidikan tauhid berupa zikir. Zikir dapat berfungsi sebagai kontrol diri karena dengan berzikir seorang hamba selalu mengingat Allah swt, segala larangan dan perintahnya, sehingga akan membuat seseorang lebih hati-hati dalam bertindak dan berperilaku. Salah satu zikir yang dapat diterapkan adalah zikir Nabi Yunus A.S, dengan zikir inilah beliau diselamatkan oleh Allah swt. dari perut ikan besar. Zikir Nabi Yunus A.S merupakan doa yang dipanjatkan oleh Nabi Yunus A.S ketika bertaubat kepada Allah swt. dari sifat yang seharusnya tidak ada dalam dirinya yaitu tidak sabar. Penelitian ini bertujuan untuk mengenalkan dan mengingatkan bahwa zikir Nabi Yunus A.S sebagai pendidikan tauhid dapat menjadi salah satu cara untuk mengatasi kecemasan pada masa Covid-19. Penelitian ini merupakan penelitian lapangan dengan menggunakan pendekatan kualitatif. Hasil penelitian menemukan bahwa; Pertama, kecemasan yang dirasakan oleh masyarakat pada masa pendemi ini masih dalam kategori wajar; Kedua, berzikir, bertaubat dan bersabar mampu membantu dalam mengatasi dan menghadapi kecemasan di masa pandemi Covid-19.
Analysis of Macroeconomic Indicators and It's Effect on Human Development Index (HDI)
Authors: Runtunuwu Prince Charles Heston
Published: January 2021

This research aims to determine the effect of inflation, per capita income. The method used is a quantitative method with a descriptive approach. The data analysis technique uses multiple linear regression models, which are continued by the classical assumption test. This research uses secondary data, precisely ten years of time-series data from 2010-2019 obtained from the Central Bureau of Statistics, books, literature, the internet, records, and other sources related. The research sample consisted of 40 data taken per quarter, from 2010-2019. The analytical method used in this research is multiple linear regressions. The results showed that inflation had a negative and insignificant effect on Human Development Index (HDI). In contrast, per capita income and unemployment had a negative and significant effect on Human Development Index (HDI). Inflation, per capita income, and unemployment significantly affected the Human Development Index (HDI) in Ternate City. The independent variable’s determination (R Square) on the dependent variable is 0.836 or 83.6%. It means inflation, per capita income, and unemployment can affect the Human Development Index (HDI) in Ternate City at 83.6%, remaining 16.4% by other factors.
Understanding the Use of Adjective Order for Senior High School 21 Makassar
Authors: Abdollah Abdollah , Yunus Muhammad , Elivan Effander
Published: January 2021

The present study is about the ordering adjective in adjective order. In this study the writer explores the students’ understanding and the student errors in the adjective order term. The writer employed pre-experimental method with one group pre-test and post-test design. The sample consisted of 40 students taken from the second class of SMA Negeri 21 Makassar, academic 2014/2015. The data were collected by giving the student test. The data collected were analyzed by using scoring classification, mean score and percentage. To find out whether fighting question method can improve student understanding in ordering adjective orders and what is the most student errors in term adjective order. The result of the data analysis showed that there was a significant difference between pre-test and post-test. The value of mean of mean score post-test (69) is greater than the pre-test (43.25) and the most students errors in adjective order term is the position of an adjective ”Shape”.
Components of increasing the competitiveness of united territorial communities under sustainable development conditions
Authors: Podzizei O.
Published: January 2021

The essence of the key components of increasing the competitiveness of the united territorial communities (UTC) under the conditions of administrative and budgetary decentralization is investigated and main UTC characteristics are revealed in this paper. Innovative principles of ensuring the UTC competitiveness under the conditions of intensification of economic and technological development are investigated. The need to reveal the essence of organizational elements and practical tools for strengthening the innovative attractiveness of territorial communities is determined. The model of tools for the formation of the innovative component of increasing the united territorial communities competitiveness of is revealed. This model includes analytical assessment of the ability of territorial communities to implement innovations, determining priorities for innovative development of territorial communities based on European Commission recommendations on smart specialization of regions, implementation of land reform principles. Based on the priority allocation of land for the implementation of innovative projects, introduction and application of geographic information systems to facilitate access to data on the UTC functioning, as well as the introduction of the concept of participatory management in the local communities activities. It is determined that the complex application of the proposed tools for promoting the innovative development of territorial communities makes it possible for them to form the development plans stimulating the increase of the UTC competitiveness level. The specifics of the general concept of labor productivity as the determinant of the regional development problem is considered and the problems of its application are determined. This is the preliminary need to ensure the effective functioning of the regional labor market. Understanding of the economic essence of «the increase of the united territorial communities competitiveness» concept is improved. It is determined that ensuring the increase of territorial communities competitiveness makes it possible to achieve successfully the tasks set before them in the process of administrative reform of the public administration system and budget decentralization.
Estimating the fiscal and regulatory role of value added tax
Authors: Lobodina Z. , Kizyma A. , Marushchak L.
Published: January 2021

The impact of value added tax (hereinafter – VAT) on the socio-economic development of the state is investigated in this paper. Here it is considered as a tool of the mechanism of budgetary resources formation and regulation of taxpayers’ welfare and activities. It is determined that, in addition to the reduction of tax rate, the public authorities and local governments should provide favorable conditions for doing business, implement measures for anticorruption and market anti-monopoly. To compensate for the expences of budgetary resources occurring as a result of possible reduction in the value added tax rate, it is necessary to look for alternative sources of pumping up the state budget. Such situation could weaken Ukraine's competitiveness, increase distrust of potential investors, and deactivate attracting investments into the country's economy. In order to stimulate certain economic activities, to increase the volume or the level of availability of certain goods (services)consumption, the tax legislation provides certain preferences for value added tax, particularly – lowering the tax rate, tax exemptions, , tax credit, tax benefits. In addition, the regulatory impact of VAT as a financial instrument on the taxation system is revealed in this paper. The peculiarities of VAT administration in Ukraine and foreign countries are highlighted, the dynamics, tendencies of receipt and reimbursement of VAT in Ukraine are considered. The reasons for tax refund arrears are given and ways to improve VAT administration are proposed. Analysis of the assessment of VAT fiscal efficiency is carried out, the indicators of the assessment of this tax fiscal efficiency are determined. Despite the permanent increase in the absolute amount of this tax and its share in gross domestic product (hereinafter – GDP) and state budget revenues, the fiscal role of VAT is weakened due to such problems as regressive impact on low-income populations, tax evasion and minimization of tax liabilities, growth of volumes of VAT refunds at the expense of budgetary resource.
刍议强化建筑工程施工的精细化施工管理
Authors: 路 闯闯 , 孙 哲祺
Published: January 2021

近年来，在多方面利好因素的影响下，使得我国各个领域都得到了显著的发展进步，从而有效推动了建筑工程施工技术和管理工作的良好发展，但是就当前整个建筑工程行业的实际情况来说，其中还存在诸多的问题需要我们加以切实的解决，诸如：施工工作人员专业素质差，缺少专门的工作规范，施工技术整体水平较低，现场施工管理工作混乱等等。经过大量的实践调查我们发现，在组织开展建筑工程施工工作的过程中，加大力度全面落实施工精细化管理，能够切实的对建筑工程施工质量加以保证，并且可以促进施工单位获得更加丰厚的经济和社会收益，对于整个建筑工程行业的持续稳定发展能够发挥出积极的辅助作用。
探析地下室人防工程结构设计的关键点
Authors: 李 伟
Published: January 2021

随着建筑质量要求逐年提升，人防工程的重要性被逐渐显现出来，人防地下室结构优化成为了设计的核心内容，在具体的建设阶段，需要掌握结构设计特点，在此基础上进行优化升级，了解设计要点以及注意事项，多角度综合考量，同时还要遵守规范要求。只有这样，才能不断提高人防工程设计水平，提升结构稳定性，确保保障功能的可靠性，将人防事业发展推向全新的高度，为现代建筑设计水平大跨度提升提供保障。
Moraitis, Anastasia; Mavruk, Gülsah; Schäfer, Andrea & Schmidt, Eva (Hg.) (2018): Sprachförderung durch kulturelles und ästhetisches Lernen. Sprachbildende Konzepte für die Lehrausbildung. Münster/New York: Waxmann
Authors: Böttcher Jeannette
Published: January 2021

Wie hängt Lehre mit Theater zusammen? Welche neuen Wege gibt es, um (Sprachen-)Lehren und Lernen zu fördern? Wie kann ich mein eigenes Lehren verbessern? Und wie kann ich meinen Schülern und Schülerinnen, aber auch meinen Lehramtsstudierenden bessere Lernmöglichkeiten bieten? Diese Fragen sollten für jeden von Interesse sein, der lehrt und lernt, der sich immer wieder mit den komplexen Beziehungen zwischen (Fremd-)Sprachenlehren und -lernen, zwischen kultureller Bildung und Integration, konfrontiert sieht. Der Sammelband Sprachförderung durch kulturelles und ästhetisches Lernen – Sprachbildende Konzepte für die Lehrerausbildung der Herausgeberinnen Anastasia Moraitis, Gülsah Mavruk, Andrea Schäfer und Eva Schmidt präsentiert in elf Beiträgen unterschiedliche Kooperationsprojekte zum Thema kulturelle und ästhetische Bildung in vielschichtigen Lehr- und Lernszenarien. In Hinblick auf ästhetisches Lehren und Lernen bietet dieses Buch sowohl theoretische Grundlagen als auch konkrete Hinweise zur praktischen Umsetzung in alltäglichen Lehr- und Lernkontexten. Die einzelnen Beiträge stellen nicht nur verschiedene Konzepte und Methoden von ästhetischem Lernen und (Fremd-)Sprachenerwerb bzw. Erziehung und Bildung vor, sondern differenzieren sie in ihren spezifischen Zielsetzungen und Potenzialen. Darüber hinaus geben sie ausführliche und leicht nachvollziehbare Anregungen für die praktische Arbeit von Lehrenden nicht nur im Schulkontext, sondern auch in der universitären Ausbildung zukünftiger Lehrerinnen und Lehrer. Die Bandbreite der Anregungen und ...
Пусть радость будет в этом доме!!!
Authors: Машкевич Татьяна
Published: January 2021

Еще совсем недавно, каких три поколения назад, здесь полнокровно клубилась светская жизнь тракайских караимов. Этот дом на ул. Караиму, 28, по своему главному предназначению являвшийся школой, в которой караимские дети постигали науку чтения и понимания Святого писания, служил и неким клубом, где до середины прошлого столетия проводились торжества, встречи, свадьбы, на просторном дворе плелись венки к празднику урожая. В те славные времена он жил насыщенной радостными событиями, праздничной суетой и содержательными буднями жизнью.
Ród Łobanosów – zagłębiając się w przeszłość
Authors: Sulimowicz Anna
Published: January 2021

Dalszy ciąg opowieści o niezwykłej rodzinie trockich wójtów, zmierzchu jej świetności po upadku Rzeczypospolitej i o rodowodzie sięgajacym być może czasów księcia Witolda.
O obyczajach w dawnym Łucku = Cynykmakłary Kart Łuckanyn
Authors: Rudkowski Sergiusz , Sulimowicz Anna
Published: January 2021

Dalszy ciąg opowieści Sergiusza Rudkowskiego o łuckich Karaimach sprzed stu pięćdziesięciu i więcej lat.
Z wyrazami wdzięczności dla Maniusia
Authors: Abrahamowicz-Pilecka Hanna
Published: January 2021

Za co kochamy członków rodziny starszych od nas o jedno pokolenie? Za sprawowanie opieki nad nami, kiedy nie potrafimy jeszcze się uporać z zagadkami dnia powszedniego, za błysk w oku w godzinach żartów, za pewność siebie, której tak chcemy się nauczyć, za genialne pomysły na spędzanie czasu wolnego, za swobodne poruszanie się w świecie zewnętrznych obowiązków, który nas wprawia w zakłopotanie. Za tysięczne inspiracje, podpowiedzi i taktowne wprowadzanie nas w dorosłość.
Przez zasłonę czasu
Authors: Dubińska Zofia
Published: January 2021

Niezapomniana Pani Zofia Dubińska nie raz nawoływała i zachęcała do spisywania wspomnień. Sama skreśliła, jak pisała w kolejnych listach do nas, podwójnych emigrantów z Ziemi trocko-wileńskiej i Warszawy, kilka obrazków z życia codziennego Karaimów w latach swojegodzieciństwa i młodości. Oto kolejny ułamek tego tematu-rzeki, jakim są wspomnienia z dawnych lat.Emilia Zajączkowska-Łopatto
Życie w trosce o ludzi
Authors: Szpakowska Ania
Published: January 2021

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Ulica Karaimska w Haliczu
Authors: Wasilczuk Nadia , Żywacziwskyj Andrij
Published: January 2021

Choć dziś mieszkają tu tylko dwie przedstawicielki halickiej społeczności, wciąż jeszcze stoją domy należące niegdyś do Karaimów.
Z archiwum Koła Pań Karaimskich w Haliczu
Authors: Sulimowicz Anna
Published: January 2021

Siedemdziesiąt pięć lat temu w nieistniejącym już Domu Gminnym w Haliczu miejscowe Koło Pań z prezeską, Sabiną Nowachowiczową na czele urządziło z okazji święta Kynysz zabawę. Zachował się tekst przemówienia wygłoszonego przypuszczalnie przez hazzana Marka Leonowicza.
Artystka niestała w uczuciach
Authors: Sulimowicz Anna
Published: January 2021

Z niewyraźnych kadrów niemego filmu dama w stylowej sukni posyła widzom piękny uśmiech. Zapomniana aktorka i pieśniarka, bratanica słynnego burmistrza, niewierna żona znanego aktora – wciąż pozostaje zagadką...
Zobaczyć Bucharę i Samarkandę
Authors: Abkowicz Anna
Published: January 2021

Mozaikowe meczety i chan-atłasy jak skrzydła motyla, czyli przygody Karaimki w Uzbekistanie.
Karaimska łyżka
Authors: Tulisow Jerzy , Majchrowska Kasia
Published: January 2021

Dawne karaimskie wesela pozostawiały niezwykłe ślady...
Zaręczynowe i weselne zwyczaje stambulskich Karaimów
Authors: Avramoğlu Çağatay Bediî , Banasiak Anna
Published: January 2021

Etnograf karaimskiego pochodzenia, Çağatay Bediî Avramoğlu w latach 60. XX w. zebrał informacje jak niegdyś wyglądały śluby i wesela.
Lejpuny i karaimski dworzanin Sapiehów
Authors: Pawelec Mariusz
Published: January 2021

Każda, nawet najdrobniejsza, wzmianka w dokumentach źródłowych dotycząca tematyki karaimskiej w dawnej Rzeczypospolitej ekscytuje i pobudza wyobraźnię. Nic dziwnego, wszak informacje takie są stosunkowo rzadkie. Zasługują one na szczególną uwagę, tym bardziej gdy przekazują je nie popularne w formie wydawnictwa, ale publikacje uznanych w świecie naukowym autorów.
Karaimskie przysłowia z Poniewieża
Authors: Sulimowicz-Keruth Anna
Published: January 2021

Pewien rękopis przysłany do Łucka w latach 30. XX w. poszerza naszą wiedzę o rodzimym folklorze i przypomina o ówczesnym młodym działaczu, Rafale Grygulewiczu.
Pamiętając o Karaimach w Haliczu
Authors: Wasilczuk Nadia , Pawelec Mariusz
Published: January 2021

Muzeum ma już 15 lat! Powstało dzięki determinacji Karaimów i ciężkiej pracy naukowców.