bluuebunny/crossref_metadata_2025 huggingface dataset:
Prediction of Future Land Use and Land Cover (LULC) in Makassar City
Authors: Nganro Sudirman , Trisutomo Slamet , Barkey Roland , Ali Mukti , Imura Hidefumi , Onishi Akio , Tsai Pei-I , Mahamud Mohd Amirul
Published: June 2021

Migration from rural area to urban area increases urban population. It increases and needs for settlements, leading to conversion of agricultural lands into settlement areas. Inconsistent land use compared with spatial planning causes change in land use. Spatial land use expansion can be monitored and predicted by modeling. NetLogo application is a software integrated with Agent-Based Modeling (ABM), which can be used to predict change of land use with various complex parameters. The present study used population growth as a parameter to predict change of land use of Makassar in 2050 based on 2017 land use classification map as the start of the prediction. The analysis result showed that the biggest change of land use happens to Settlement class which is 594.74 hectares and the smallest is Water Body class which is 8.76 hectares.
Countering Acts of Dispossession through Alberto Blest Gana’s Mariluán
Authors: DeLutis-Eichenberger Angela N.
Published: June 2021

In the scant scholarship relative to Alberto Blest Gana’s Mariluán, several critics have underscored the unfeasibility or superfluidity of the protagonist’s aspired project for restitution, indigenous assimilation, and fraternity in the Araucanía during the novel’s context of enunciation. Under the theoretical framework of Athena Athanasiou and Judith Butler on dispossession, and in dialogue with the concept of “sediments of time” by Reinhart Koselleck, this study argues that an analysis of the overlapping chronologies in “play” in Mariluán serves to revise the statements seemingly offered for advancement nearly 160 years ago. Mariluán’s pseudo-revival of a Lautaro and the manner in which he makes himself “present” or “becoming,” and remains “present” after his beheading, can be re-signified as a means to challenge the terms imposed from structures that inhibit, subjugate, and seek to fully exterminate or nullify the “other” – insomuch in the 1860s, as in future temporalities involving repetitions of historical events and their related, yet distinguishable, singularities. Through a reconsideration of the protagonist’s aims that refute his call for cultural assimilation as a necessary means of integration, today’s status quo on indigenous issues can be re-problematised, to contest the pervasive logic of dispossession and advocate for more practical and politically inclusive structures that celebrate Chile’s plurality.
On some fixed point theorems for multivalued F-contractions in partial metric spaces
Authors: Kumar Santosh , Luambano Sholastica
Published: June 2021

Altun et al. explored the existence of fixed points for multivalued

F

F

-contractions and proved some fixed point theorems in complete metric spaces. This paper extended the results of Altun et al. in partial metric spaces and proved fixed point theorems for multivalued

F

F

-contraction mappings. Some illustrative examples are provided to support our results. Moreover, an application for the existence of a solution of an integral equation is also enunciated, showing the materiality of the obtained results.
Aspectual cognate objects in Hungarian
Authors: Farkas Imola-Ágnes
Published: June 2021

This paper examines aspectual cognate objects in Hungarian. Its main contribution lies in the syntactic and semantic analysis of three classes of accusative pseudo-objects, which are literally not cognate with the prototypical unergative verb they accompany but are demonstrated to be non-subcategorized and non-thematic elements that have the same role and the same syntactic and semantic properties as aspectual cognate objects in languages where these nominals are both semantically and morphologically related to the verb. In addition, the paper fills a typologically unexpected gap, considering that Hungarian, as a strong satellite-framed language, is predicted to have aspectual cognate object constructions.
Pulmonary parenchymal involvement caused by Tropheryma whipplei
Authors: Zhang Wen Mei , Xu Ling
Published: June 2021

We report a 26-year-old man with left chest pain for 4 days. His chest CT showed a cavity in the left upper lung. Tuberculosis was suspected first, but metagenomics next generation sequencing (mNGS) in bronchoalveolar lavage fluid only detected Tropheryma whipplei. Tropheryma whipplei is the pathogen of Whipple’s disease. The most frequently involved organs are the eyes, heart, and central nervous system. Pulmonary parenchymal involvement is rare. To our knowledge, this is the first reported case of pulmonary cavity caused by Tropheryma whipplei. Nineteen cases of pulmonary parenchymal involvement were found by literature search. The most common respiratory symptom was cough, followed by dyspnea/breathlessness and chest pain. The most common finding in chest imaging was pulmonary nodules, followed by interstitial changes and patchy infiltration. Our case and literature review highlighted that Tropheryma whipplei infection should be considered in the differential diagnosis of pulmonary cavity, pulmonary nodules, interstitial changes, and patchy infiltration. mNGS is helpful to improve diagnosis rate.
Social deprivation and paediatric chronic pain referrals in Ireland: a cross-sectional study
Authors: Matthews Eveline , Muldoon Maeve , O’Keeffe Norma , McCarthy Kevin F.
Published: June 2021

Objectives

Social deprivation is associated with a higher prevalence of chronic pain in children and an under-representation in specialist paediatric chronic pain programs. Our primary objective was to determine if there was a relationship between social deprivation and paediatric chronic pain referrals in Ireland. Secondary objectives included analysing for differences between deprivation groups in pain characteristics and function that are recorded at first clinic visit.

Methods

Families attending the national paediatric complex pain service in Dublin, Ireland, complete questionnaires on pain characteristics, parental pain catastrophizing, and pain-related disability including sleep quality and school attendance. We retrospectively reviewed records from between February 2016 and November 2019 on 288 patients. Social deprivation was assessed using the Pobal HP Deprivation Index, which is based on data from the Irish national census.

Results

Referrals followed a normal distribution across deprivation grades. Children in the disadvantaged group had a longer duration of pain, greater use of screens at bedtime, and longer sleep onset latency. Parents in the disadvantaged group had significantly higher levels of parental pain catastrophizing.

Conclusions

In Ireland, while paediatric chronic pain referrals were normally distributed across deprivation group, the disadvantaged group was different in several ways that may be clinically significant. Further work will be needed to determine the longitudinal relationship between these factors before and after the referral and initial review. Screening for, and targeting, potential risk factors for pain chronicity may be needed to harmonize treatment outcomes in children from socially disadvantaged families.
A preliminary study of Salmonella spp., Listeria monocytogenes, Escherichia coli O157, Enterococcus faecalis and Clostridium spp. in Irish cattle
Authors: Russell L. , Galindo C.P. , Whyte P. , Bolton D.
Published: June 2021

Although Salmonella spp., Escherichia coli O157, Listeria monocytogenes, Enterococcus faecalis and Clostridium spp. present a significant food safety and/or spoilage issue for the beef sector, there are limited data on their prevalence in Irish cattle. The objectives of this preliminary study were to investigate the distribution (percentage of farms positive) of Salmonella spp., E. coli O157, L. monocytogenes, E. faecalis and Clostridium spp. and the overall prevalence (%) of these bacteria in cattle on a small cohort of Irish beef farms. A total of 121 fresh bovine faecal samples were obtained on 10 randomly selected beef farms in the Northeast of Ireland and tested for the target pathogens using standard culture-based methods. Presumptive positives were confirmed using previously published polymerase chain reaction (PCR) methods. Salmonella were not detected in any of the samples. E. coli O157, L. monocytogenes, E. faecalis and Clostridium spp. were present on 50%, 40%, 100% and 100% of farms, respectively, with overall (all farms) prevalence rates in cattle of 9%, 8.2%, 61.9% and 87.6%, respectively. This study suggests that E. coli O157 may be more prevalent than previously thought and L. monocytogenes, E. faecalis and Clostridium spp. are widespread in Irish beef animals.
The occurrence of herbicide-resistant Avena fatua (wild oats) populations to ACCase-inhibiting herbicides in Ireland
Authors: Byrne R. , Vijaya Bhaskar A.V. , Spink J. , Freckleton R. , Neve P. , Barth S.
Published: June 2021

Following growers’ reports of herbicide control problems, populations of 30 wild oats, Avena fatua, were collected from the south-east main arable counties of Ireland in 2016 and investigated for the occurrence and potential for herbicide resistance to acetyl-CoA carboxylase (ACCase) inhibitors pinoxaden, propaquizafop and cycloxydim, as well as acetolactate synthase (ALS) inhibitor mesosulfuron + iodosulfuron. Plant survival ≥20% was considered as the discriminating threshold between resistant and susceptible populations, when plants were treated with full recommended field rates of ACCase/ALS inhibitors. Glasshouse sensitivity screens revealed 2 out of 30 populations were cross-resistant to all three ACCase inhibitors. While three populations were cross-resistant to both pinoxaden and propaquizafop, and additionally, two populations were resistant to propaquizafop only. Different degree of resistance and cross-resistance between resistant populations suggest the involvement of either different point mutations or more than one resistance mechanism. Nevertheless, all populations including the seven ACCase-resistant populations were equally susceptible to ALS inhibitor. An integrated weed management (cultural/non-chemical control tactics and judicious use of herbicides) approach is strongly recommended to minimize the risk of herbicide resistance evolution.
The Roles of Capital Intensity in Moderating Managerial Ownership and Investment Opportunity Set (IOS) on Accounting Conservatism
Authors: Sholikhah Zahrotus , Baroroh Niswah
Published: June 2021

This study aims to examine the effect of managerial ownership and investment opportunity set (IOS) on accounting conservatism with capital intensity as a moderating variable. The population was the manufacturing companies listed in the Indonesia Stock Exchange (IDX) from 2016-2018 as many as 184 companies. The sampling technique was purposive sampling technique and selected 39 units of analysis from 16 companies. The collection of research data used documentation technique. The analysis of research data used descriptive statistics and inferential statistics. The hypothesis testing used moderating regression analysis with an absolute difference test using IBM SPSS 24 tools. The results showed that investment opportunity set (IOS) had a significant positive effect while managerial ownership did not affect on accounting conservatism. Capital intensity could not significantly moderate the effect of managerial ownership and investment opportunity set (IOS) on accounting conservatism. Based on the result of this research, the conclusion is investment opportunity set (IOS) has a significant positive effect on accounting conservatism. The companies with higher investment opportunity sets (IOS) are able to increase the application of the accounting conservatism principles.

Keyword: Accounting Conservatism; Managerial Ownership; Investment Opportunity Set (IOS); Capital Intensity
Corporate Social Responsibility Disclosure, Corporate Governance Disclosures, and Firm Value In Indonesia Chemical, Plastic, and Packaging Sub-Sector Companies
Authors: Firmansyah Amrie , Husna Mitsalina Choirun , Putri Maritsa Agasta
Published: June 2021

This study aims to examine environmental disclosure, social disclosure, economic disclosure, and corporate governance disclosures on the firm value in Indonesia. This study uses a quantitative method with multiple regression. This study employs data from chemical, plastic, and packaging sub-sector companies which listed in the IDX. After purposive sampling was conducted, the final sample consists of eleven companies from 2016 up to 2019. The result suggests that environmental disclosure positively affects firm value. Meanwhile, economic and social disclosures do not affect firm value. Also, the disclosure of corporate governance does not affect firm value. The companies should consider that environmental activities as a strategy for the company, and these activities show that the company's success in the capital market is related to investors' positive response.

Keywords: Corporate Governance, Economic, Environmental, Social, Disclosure
Leverage as a Moderator of the Effect of Company Size, Managerial Ownership, and Conflict of Interest on Accounting Conservatism
Authors: Sari Siti Nurmala , Agustina Linda
Published: June 2021

This study aims to examine the influence of company size, managerial ownership, and conflict of interest to accounting conservatism with leverage as the moderating variable. The population was mining companies and infrastructure, utilities, and transportation companies which were listed on the Indonesia Stock Exchange (IDX) from 2015 to 2018, which are 118 companies. The sample was determined by purposive sampling which resulted in 12 companies with 36 units of analysis. The data were collected by using documentaries. The analysis techniques used descriptive and inferential with the help of IBM SPSS version 21. The results showed that managerial ownership had a negative influence and conflicts of interest had a positive influence to accounting conservatism, company size had not influenced to accounting conservatism, and leverage moderated the relationship of managerial ownership to accounting conservatism, but it was unable to moderate the relationship of company size and conflict of interest to accounting conservatism. The conclusion of this study is the low managerial ownership presses the existence of expropriation; therefore, it can increase the accounting conservatism. The high conflict of interest increases the application of accounting conservatism to reduce conflicts that occur. Meanwhile, leverage influences the company’s financial risk, therefore it is able to moderate the influence of managerial ownership to accounting conservatism.

Keywords: Accounting Conservatism; Company Size; Conflict of Interest; Leverage; Managerial Ownership
Clinical and hormonal findings in patients presenting with high IGF-1 and growth hormone suppression after oral glucose load: a retrospective cohort study
Authors: Carosi Giulia , Mangone Alessandra , Sala Elisa , Del Sindaco Giulia , Mungari Roberta , Cremaschi Arianna , Ferrante Emanuele , Arosio Maura , Mantovani Giovanna
Published: June 2021

Objective

High insulin-like growth factor 1 (IGF-1) and unsuppressed growth hormone (GH) levels after glucose load confirm the diagnosis of acromegaly. Management of patients with conflicting results could be challenging. Our aim was to evaluate the clinical and hormonal evolution over a long follow-up in patients with high IGF-1 but normal GH nadir (GHn < 0.4 μg/L according to the latest guidelines).

Design

Retrospective cohort study.

Methods

We enrolled 53 patients presenting high IGF-1 and GHn < 0.4 μg/L, assessed because of clinical suspicion of acromegaly or in other endocrinological contexts (e.g. pituitary incidentaloma). Clinical and hormonal data collected at the first and last visit were analyzed.

Results

At the first evaluation, the mean age was 54.1 ± 15.4 years, 34/53 were females, median IGF-1 and GHn were +3.1 SDS and 0.06 μg/L, respectively. In the whole group, over a median time of 6 years, IGF-1 and GHn levels did not significantly change (IGF-1 mean of differences: −0.58, P = 0.15; GHn +0.03, P = 0.29). In patients with clinical features of acromegaly, the prevalence of acromegalic comorbidities was higher than in the others (median of 3 vs 1 comorbidities per patient, P = 0.005), especially malignancies (36% vs 6%, P = 0.03), and the clinical worsening overtime was more pronounced (4 vs 1 comorbidities at the last visit).

Conclusions

In patients presenting high IGF-1 but GHn < 0.4 μg/L, a hormonal progression is improbable, likely excluding classical acromegaly in its early stage. However, despite persistently low GH nadir values, patients with acromegalic features present more acromegalic comorbidities whose rate increases over time. Close clinical surveillance of this group is advised.
microRNAs involved in psoriasis and cardiovascular diseases
Authors: Sileno Sara , Beji Sara , D’Agostino Marco , Carassiti Alessandra , Melillo Guido , Magenta Alessandra
Published: June 2021

Psoriasis is a chronic inflammatory disease involving the skin. Both genetic and environmental factors play a pathogenic role in psoriasis and contribute to the severity of the disease. Psoriasis, in fact, has been associated with different comorbidities such as diabetes, metabolic syndrome, gastrointestinal or kidney diseases, cardiovascular disease (CVD), and cerebrovascular diseases (CeVD). Indeed, life expectancy in severe psoriasis is reduced by up to 5 years due to CVD and CeVD. Moreover, patients with severe psoriasis have a higher prevalence of traditional cardiovascular (CV) risk factors, including dyslipidemia, diabetes, smoking, and hypertension. Further, systemic inflammation is associated with oxidative stress increase and induces endothelial damage and atherosclerosis progression. Different miRNA have been already described in psoriasis, both in the skin tissues and in the blood flow, to play a role in the progression of disease. In this review, we will summarize and discuss the most important miRNAs that play a role in psoriasis and are also linked to CVD.
Film formation and foamability of cellulose derivatives: Influence of co-binders and substrate properties on coating holdout
Authors: Lyytikäinen Johanna , Ovaska Sami-Seppo , Heiskanen Isto , Backfolk Kaj
Published: June 2021

Foams were prepared from hydrophobically modified ethyl(hydroxyethyl) cellulose (EHEC), methyl nanocellulose, and native microfibrillated cellulose (MFC). Their film- and foam-forming abilities, stabilities, and suitabilities for foam coating on different substrates were investigated. The role of EHEC as a polymeric stabilizing agent was also studied. The EHEC-MFC foams showed greater stability and water-holding ability under pressurized dewatering than MFC foams prepared in the presence of a surfactant. A foam could be created with methyl nanocellulose without any foaming agent. Selected nanocellulose gels and foam formulations were used to coat various substrates. The surface was efficiently closed by gel and foam coatings prepared from the methyl nanocellulose and EHEC solutions, which was ascribed to good coating holdout. Coatings on papers with different levels of smoothness/density and hydrophobicity/ hydrophilicity confirmed that foam-substrate interactions affected the coat quality. The air permeance was reduced by 99% and 64% with a methyl nanocellulose coating and an EHEC-MFC coating, respectively. An EHEC-MFC coating created a hydrophobic surface on a hydrophilic substrate, and methyl nanocellulose improved the oil resistance even at a low coat weight.
Research progress on the dairy cow mastitis
Authors:   Sumy National Agrarian University, Faculty of Veterinary Medicine, 160 Herasima Kondratieva str., Sumy, 40021, Ukraine, Ping Xu
Published: June 2021

Mastitis is an inflammatory disease of the mammary gland, which has a significant economic impact and is an animal welfare concern. Mammary gland development and regression was directly related with cow lactation. Many different microbial and environmental factors can induce mastitis. Escherichia coli and Staphylococcus aureus were the main cause of mastitis. The treatment of clinical and subclinical mastitis mainly focuses on the use of antibiotics. At present, although some progress has been made in the clinical diagnosis, antibiotic treatment, and pathogenesis control of dairy cow mastitis, the molecular mechanism of the pathogenicity of dairy cow mastitis was still not very clear. So, it is important to understand the mechanisms controlling the immune response at the molecular level. Non-coding RNAs play an important role in various biological processes, including cell proliferation, differentiation and apoptosis. However, their functions and profiles in dairy cows are largely unknown. This study reviewed the research progress of the pathogenesis, prevention measures and immune mechanism of dairy cow mastitis.
ВПЛИВ ДОБАВОК СОЛЕЙ НАТРІЮ НА ВЛАСТИВОСТІ ПОКРИТТІВ З ВМІСТОМ ВІДХОДІВ ВИРОБНИЦТВ
Authors: І. Кольцова Ярослава
Published: June 2021

У роботі досліджено вплив добавок солей натрію на оптико-колірні властивості покриттів, що вміщують бій скла, глинисті матеріали та відходи виробництв:  гранульований доменний шлак, відвальний шлак виробництва феросилікомарганцю, паливний шлак та золу-унесення теплоелектростанції, а також гранітний відсів. Для проведення досліджень було обрано солі натрію: Na2CO3, NaNO3, Na2SO4, NaCl, які вводили в кількостях, що відповідають вмісту 1.5; 3 та 6 мас. ч. Na2O. Встановлено, що підвищення вмісту введеного солями Na2O понад 1.5 мас. ч. погіршує реологічні властивості шлікеру та якість покриттів. Визначено, що вид аніону (СОз2–, NO3–, SO42–, Cl–) при незмінному катіоні Na+ досліджених солей незначно впливає на оптико-колірні властивості покриттів, але більш якісну поверхню покриттям надає введення Na2O за допомогою Na2CO3. Добавки солей натрію сприяють незначному освітленню кольору дослідних покриттів, але не призводять  до підвищення блиску за температури випалу 1000 оС, крім вихідного покриття без вмісту відходів виробництв.
АДСОРБЦІЯ ИОНОВ МЕТАЛІВ Co, Ni, Cu, Zn НА ФУЛЕРЕНІ C60 І НА ОДНОСТІННІЙ ВУГЛЕЦЕВІЙ НАНОТРУБЦІ C48 ЯК ДІЮЧА СИЛА ЕЛЕКТРООСАДЖЕННЯ КОМПОЗИЦІЙНИХ ПОКРИТТІВ
Authors: В. Титаренко Валентина , П. Штапенко Едуард , О. Воронков Євген , Вангара Аруна , А. Заблудовський Володимир , Колоджейчик Войцех , Капуста Каріна , І. Оковитий Сергій
Published: June 2021

Досліджено композиційні плівки, осаджені у водних розчинах електролітів, що містять іони металів і частинки вуглецевих наноматеріалів, таких як фулерен C60. Результати дослідження катодних поляризаційних кривих показали збільшення опору переносу заряду. Аналіз фазового складу металевих плівок показав наявність вуглецевих наночастинок (ВНЧ) всередині металевої матриці і значні зміни у кристалічній решітці. З результатів дослідження мікрофотографій слідує, що додавання ВНЧ змінює структуру росту металевих плівок від стовбчатої ​​до мікрошаруватої через пасивацію поверхні. У даній роботі теорія функціонала густини (ТФГ) була використана для розрахунку термохімічних, електронних і структурних властивостей комплексів іонів металів з ВНЧ. Результати розрахунків енергії зв'язку комплексів ВНЧ- Me2+ дозволяють припустити, що адсорбція іонів Co2+, Ni2+, Cu2+ та Zn2+ на поверхні фулерену C60 і одностінної вуглецевої нанотрубки (ОВНТ) C48 можлива і термодинамічно вигідна. Було виявлено, що енергія зв'язку більша у разі адсорбції іона металу на поверхні ОВНТ C48, у порівнянні з адсорбцією на фулерені C60. Оскільки комплекси Cu2+ були найбільш термодинамічно стабільними, енергія зв'язку зростала у такій послідовності Co2+<Zn2+<Ni2+<Cu2+. Результати розрахунків вільної енергії зв'язку показали хорошу кореляцію з шириною забороненої зони, відстанями між іоном металу і поверхнею ВНЧ, дипольними моментами, делокализацією заряду у методі природних орбіталей (МПO) і другим потенціалом іонізації іонів металів.
Re-creando la receta de una mantecada vegetariana. La cocina como espacio de negociación de conocimientos y para el conocimiento
Authors: Daza Sandra
Published: June 2021

Este artículo piensa la cocina y el cocinar como escenarios de producción, circulación, negociación y subversión de conocimientos. Igualmente, señala la necesidad de una “antropología de la cocina” que reconoce el acto de cocinar y la cocina misma como asuntos importantes para la reflexión teórica. Para ello, se pregunta qué es una mantecada vegetariana y describe su preparación en una clase de cocina en Bogotá, Colombia. Primero señala que la receta escrita, a pesar de ser un dispositivo en apariencia estable, es infinitamente adaptable y está en continua transformación. Luego, mediante la recreación de la receta, se detiene en el proceso de traducción y negociación de su preparación para reflexionar sobre la cocción como un acto de coordinación entre cuerpos, ingredientes, utensilios y ambientes, y analiza cómo en tal proceso se comparten, emergen y negocian conocimientos. Finalmente, propone que cada preparación es un ensamblaje efímero que se completa solo cuando cada comensal lo lleva a la boca y nos recuerda a quienes nos dedicamos al saber académico que aún nos faltan palabras para referirnos a lo sensual y subjetivo.
Tactics of surgical treatment of hysteromyoma at women with disturbance of genesial function
Authors:   Shupyk National Medical Academy of Postgraduate Education, Kуiv, Ukraine, Litvak E.O. , Dovgan A.A. ,   Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine
Published: June 2021

The objective: to increase efficiency of surgical treatment of hysteromyoma at women of genesial age on the basis of preoperative use medicamental correction. Materials and methods. Сlinical-laboratory and functional examination of 130 women of genesial age was conducted, at 100 from which there was diagnostic hysteromyoma. 1 (main) group was made by 50 women with a hysteromyoma at whom in addition used as preoperative preparation a preparation which contains ulipristalacetat in a dosage of 5 mg per day within 12 weeks. 2 (comparisons) group made also 50 women with a hysteromyoma who received preoperative preparation gestagens. The control group was made by 30 women of similar genesial age without gynecologic pathology. Results. Introduction in clinical practice of preoperative preparation by preparation ulipristalacetat with the subsequent combined operative measure (hystero-laparoscopy) in one stage with applying of endoscopic seams on a wall of a uterus promotes depression of an intraoperative hemorrhage; to decrease to the volume of infusional therapy and early restoration of fertility function of patients. Conclusion. Use of the algorithm improved by us will allow to increase efficiency of treatment of sterility at women with hysteromyoma. Key words: hysteromyoma, sterility, surgical treatment.
Optimisation of the diagnostic and therapeutic algorithm for dealing with psychogenic amenorrhea from the standpoint of the interdisciplinary approach
Authors:   Clinical Hospital Feofaniya, Kyiv, Ukraine, Vedeneieva Z.M. , Prima I.V. ,   Clinical Hospital Feofaniya, Kyiv, Ukraine, Goncharenko V.M. ,   Clinical Hospital Feofaniya, Kyiv, Ukraine, Kravchenkо Yu.V. ,   Clinical Hospital Feofaniya, Kyiv, Ukraine
Published: June 2021

The objective: was to optimize the treatment of patients with post-stress disorders of menstrual function by conducting pathogenetic complex therapy from the perspective of an interdisciplinary approach. Materials and methods. 54 women aged 19-37 years with psychogenic amenorrhea (PA) – the main group – were examined. The control group included 25 practically healthy patients aged 18 to 35 years. Results. The variants of hormonal disorders in this pathology are determined, the analysis of the results of electroencephalography and the study of individual and reactive anxiety in patients with PA are performed. The presence of three pathogenetic variants of hormonal disorders was established, which became the criterion of the proposed differentiated pathogenetic treatment. Conclusion. Features of the pathogenesis of psychogenic amenorrhea, the complexity of neuroendocrine and hormonal disorders indicate the need for an interdisciplinary approach in the examination, treatment and rehabilitation of this category of patients with the involvement of related specialists – a neurologist and psychotherapist. Key words: amenorrhea, stress, Noofen®, Cyclodinone, electroencephalography, reactive anxiety, individual anxiety, hyperprolactinaemia, hypercortisolemia.
Substitution therapy with levothyroxine in balancing of hormonal interactions at subclinical hypothyroidism in reproductive-age women
Authors:   Bogomolets National Medical University, Kyiv, Ukraine, Ventskovskii B.M. , Varchenko L.M. ,   Kyiv City Clinical Endocrinology Center, Kyiv, Ukraine
Published: June 2021

6 months levothyroxine appointment in 80 reproductive-age women with subtypical hypothyroidism contributed to the normalization of hormonal interactions in the pituitary-ovarian axis with the elimination of reproductive system disorders in 58.8% cases. Hormonal disorders with hyperprolactinemia persisted in 41.2% of women, so they continued substitution therapy with the inclusion of selective dopamine receptor blocker of cabergoline. After 9, and even more after 12 months of this treatment, both the normalization of the hormonal profile and the elimination of clinical manifestations of disorders in the reproductive system were achieved. Key words: hyperprolactinemia, cabergoline, menstrual disorders, reproductive system, hormones.
Remarks on conformal anti-invariant Riemannian maps to cosymplectic manifolds
Authors: GÜNDÜZALP Yılmaz , AKYOL Mehmet Akif
Published: June 2021

M.A. Akyol and B. Şahin [Conformal anti-invariant Riemannian maps to Kaehler manifolds, U.P.B. Sci. Bull., Series A, Vol. 80, Iss. 4, 2018] defined and studied the notion of conformal anti-invariant Riemannian maps to Kaehler manifolds. In this paper, as a generalization of totally real submanifolds and anti-invariant Riemannian maps, we extend this notion to almost contact metric manifolds. In this manner, we introduce conformal anti-invariant Riemannian maps from Riemannian manifolds to cosymplectic manifolds. In order to guarantee the existence of this notion, we give a non-trivial example, investigate the geometry of foliations which are arisen from the definition of a conformal Riemannian map and obtain decomposition theorems by using the existence of conformal Riemannian maps. Moreover, we investigate the harmonicity of such maps and find necessary and sufficient conditions for conformal anti-invariant Riemannian maps to be totally geodesic. Finally, we study weakly umbilical conformal Riemannian maps and obtain a classification theorem for conformal anti-invariant Riemannian maps.
Volterra operators between limits of Bergman-type weighted spaces of analytic functions
Authors: KIZGUT Ersin
Published: June 2021

We characterize continuity and compactness of the Volterra integral operator $T_g$ with the non-constant analytic symbol $g$ between certain weighted Fréchet or (LB)-spaces of analytic functions on the open unit disc, which arise as projective (resp. inductive) limits of intersections (resp. unions) of Bergman spaces of order $1<p<\infty$ induced by the standard radial weight $(1-|z|^2)^\alpha$ for $0<\alpha<\infty$. Motivated from the earlier results obtained for weighted Bergman spaces of standard weight, we also establish several results concerning the spectrum of the Volterra operators acting on the weighted Bergman Fréchet space $A^p_{\alpha+}$, and acting on the weighted Bergman (LB)-space $A^p_{\alpha-}$.
$\mathcal{F-}$relative $\mathcal{A-}$summation process for double sequences and abstract Korovkin type theorems
Authors: YILDIZ Sevda
Published: June 2021

In this paper, we first introduce the notions of $\mathcal{F-}$relative modular convergence and $\mathcal{F-}$relative strong convergence for double sequences of functions. Then we prove some Korovkin-type approximation theorems via $\mathcal{F-}$relative $\mathcal{A}-$summation process on modular spaces for double sequences of positive linear operators. Also, we present a non-trivial application such that our Korovkin-type approximation results in modular spaces are stronger than the classical ones and we present some estimates of rates of convergence for abstract Korovkin-type theorems. Furthermore, we relax the positivity condition of linear operators in the Korovkin theorems and study an extension to non-positive operators.
Addendum to "$\alpha-$Topological Vector Spaces''[Hacet. J. Math. Stat. 47 (5), 1102-1107, 2018]
Authors: RAM Madhu
Published: June 2021

In this article, we give the corrected version of Theorem 3.5 and Theorem 3.7 (a) in [$\alpha-$Topological vector spaces, Hacet. J. Math. Stat. 47 (5), 1102-1107, 2018] by T. Al-Hawary.
Vakfiyeleri Işığında II. Bayezid’in Eşi Bülbül Hatun Vakıfları
Authors: GÜNDÜZ Ahmet
Published: June 2021

Bülbül Hatun II. Bayezid’in hanımı ve Şehzade Ahmed’in annesidir. Şehzade Ahmed Amasya’da sancakbeyi iken oğlunun yanında kalmıştır. Hayırsever bir kişiliğe sahiptir. Bütün mal varlığını Amasya ve Lâdik’te inşa ettirdiği hayır kurumlarının devamı için vakfetmiştir. Kurduğu vakfın işleyişi hakkında 1511 ve 1513 tarihlerinde iki vakfiye tanzim etmiştir. Vakfiyelerinde; vakıf mallarının neler olduğu, vakıf görevlileri, yapacakları işler, alacakları ücretler ve imaretten yararlanacak kişiler ayrıntılı olarak açıklanmıştır.Bu çalışmada Vakıflar Genel Müdürlüğü ve Cumhurbaşkanlığı Devlet Arşivleri Başkanlığı Osmanlı Arşivinde bulunan vakfiyeler ışığında Bülbül Hatun’un vakıf eserleri, gelir kaynakları, vakıf görevlileri, vazifeleri, ücretleri ve imaretin işleyiş şekli ele alınmıştır. Ayrıca, vakıf muhasebe bilanço defterlerinden faydalanılarak vakfın gelir ve giderleri üzerinde durulmuştur.
NEW DATA ON CHRONOLOGY OF NEOLITHIC CULTURE OF THE KAMA REGION
Authors:   Perm State University, Lychagina E. L. ,   Perm State Humanitarian Pedagogical University, Vybornov A. A. ,   Samara State University of Social Sciences and Education, Kulkova M. A. ,   Herzen Russian State Pedagogical University
Published: June 2021

The article presents new radiocarbon dates obtained on the materials of the Volgo-Kamskaya and Kamskaya Neolithic cultures in the Kama River basin. In the paper, the data of original material for dating and methods were considered. Eleven new radiocarbon dates from eight Neolithic sites of region were obtained. The sites are located on the territory of the Upper Kama River basin (4 archaeological sites), the Kama-Vyatka basin (2 archaeological sites), and the Lower Kama River basin (2 archaeological sites). The main material for radiocarbon dating was the organics from pottery. Together with radiocarbon dates on organics from pottery, the dates on charcoal and animal bones were obtained. The dates on different organic materials have a good correlation. These results are new data for the early and developed stages of the Kamskaya culture. The earliest dates were obtained for unornamented pottery of the Volga-Kamskaya culture. This can be an evidence of priority of this culture in respect of pottery production in the Kamariver basin. This suggestion is confirmed by archaeological materials from neighbour regions. On other hand, the results of radiocarbon dating allow authors to conclude about synchronic existence of ceramic traditions with pinned and combed ornamentation from the middle of 6th to the middle of 5th millennium BC in region under consideration. However, the sites with pinned ornamented pottery appeared in the region earlier than the sites with ceramics ornamented by comb. The investigations gave the possibility to determine the time of appearance of sites with collarlike corolla pottery and pit-combed ornamented pottery in the Kama river region. The appearance of this type of ceramics in the region testifies to the contacts of the Kamskaya Neolithic culture community with people from the southern and eastern regions.
New Archaeocyatha Findings from the Oldyndinskaya Suite (Western Transbaikalia)
Authors:   Geological Institute SB RAS, Skripnikov M. S. , Vetluzhskikh L. I. ,   Geological Institute SB RAS
Published: June 2021

Archaeocyatha Sajanolynthus desideratus, Nochoroicyathus arteintervallum, Sibirecyathus abacanicus, Stapicyathus abakanensis, Leptosocyathellus mirandus, Cyclocyathella jakovlevi, Plicocyathus admirabilis, Sanarkocyathus sp., Annulocyathella lavrenovae, Clathricoscinus vassilievi, Usloncyathus sp. Indet in the limestones of the Lower Cambrian Oldynda Suite (Western Transbaikalia) were discovered for the first time that makes it possible to contribute to the characteristics of the Oldyndinskaya Suite biodiversity, and determine a closer relationship between paleobasins of the margins of the Siberian Platform in the Early Cambrian.
The Phenomenon of Petrovskiy (to the 75th Anniversary)
Authors:   Institute of geology of FRC Komi Scientific Centre of Ural Branch of the Russian Academy of Sciences., Sukharev A. E. , Silaev V. I. ,   Institute of geology of FRC Komi Scientific Centre of Ural Branch of the Russian Academy of Sciences., Khazov A. F. ,   Institute of geology of FRC Komi Scientific Centre of Ural Branch of the Russian Academy of Sciences.
Published: June 2021

Brief scientific biography of a well-known scientist, a leader in the field of experimental study of crystallization processes with usage the holographic method for quantitative analysis of temperature-convective inhomogeneities in the «growth-criticalstone» system, a specialist in crystallographic-mineralogical study of diamonds and their accessory minerals, a successful researcher of modern mineral formation at Kamchatka volcanoes, one of the founders of the «literally from scratch» enterprise for the production of industrial diamonds.
DİŞ HEKİMLİĞİ ÖĞRENCİLERİNİN ENGELLİLERE YÖNELİK TUTUMLARININ BELİRLENMESİ
Authors: KÜRKÇÜOĞLU Işın , ERGAN Mesut , ELMAS ALSINI Tuğçe Gül , KESKİN Tahir , ALSINI Abdullah Mayunan , BAŞKURT Ferdi
Published: June 2021

Amaç

Diş hekimliği öğrencilerinin engelli kişilere yönelik tutum

ve davranışlarının belirlenmesi, engelli bireylere

gelecekte verecekleri sağlık hizmetinin kalitesinin

geliştirilebilmesi açısından önemlidir. Bu çalışmanın

amacı bir diş hekimliği fakültesinde öğrenim gören

öğrencilerin engellilere yönelik tutumlarını belirlemektir.

Gereç ve Yöntem

Tanımlayıcı araştırma olarak tasarlanan bu çalışma,

Süleyman Demirel Üniversitesi Diş Hekimliği Fakültesi’nde

öğrenim gören 179 öğrencinin katılımıyla gerçekleştirilmiştir.

Araştırmanın verileri, Sosyo - Demografik

Veri Formu ve Yetersizlikten Etkilenmiş Kişilere

Yönelik Tutum Ölçeği (YEKYTÖ) kullanılarak toplanmıştır.

Verilerin istatistiksel analizinde, iki gruba ait

olan ortalamaların karşılaştırılmasında t testi, üç veya

daha fazla grubun ortalamalarının karşılaştırılmasında

ise tek yönlü ANOVA testi kullanılmıştır.

Bulgular

Araştırmaya katılan öğrencilerin %57,5’i kadın,

%42,5’i erkek olup yaş ortalamalarının 22,24±1,67

yıl olduğu belirlenmiştir. Öğrencilerin YEKYTÖ puan

ortalamasının 60,15±12,76 olduğu, YEKYTÖ puanlarının

cinsiyet, engellilik durumu, staj yapılan birimde

birlikte çalışılan engelli birey olması, ailede engelli birey

olması, öğrenim görülen sınıf ve anne-baba eğitim

durumu gibi değişkenlere göre istatistiksel olarak

anlamlı düzeyde farklılık göstermediği tespit edilmiştir

(p>0,05).

Sonuç

Araştırmamızın sonuçlarına göre çalışmamıza konu

olan diş hekimliği öğrencilerinin engellilere yönelik

tutumlarının orta düzeyde olduğu belirlenmiştir. Diş

hekimliği öğrencilerinin tutumlarının, engelli bireylere

yaklaşımla ilgili bilgilendirmeler yapılarak ve engelli

hastaların dental tedavilerine yönelik teorik ve pratik

eğitimler ve rehberlik verilerek geliştirilebileceği düşünülmektedir.
Combined 3D-QSAR and Molecular Docking Analysis of Thienopyrimidine Derivatives as Staphylococcus aureus Inhibitors
Authors: Ouassaf Mebarka , Belaidi Salah , Khamouli Saida , Belaidi Houmam , Chtita Samir
Published: June 2021

The discovery of antibacterials is considered one of the greatest medical achievements of all time. In this work, a combination of three computational analyzes: 3D-QSAR, molecular docking and ADME evaluation were applied in thienopyrimidine derivatives intended toward gram-positive bacterium Staphylococcus aureus. The validity of 3D-QSAR model was tested with a set of data which is divided into a training and a test set. The two models constructed (CoMFA and CoMSIA) show good statistical reliability (q2 = 0.758; r2 = 0.96; r2pred = 0.783) and (q2 = 0.744; r2 = 0.97; r2pred = 0.625) respectively. In addition, docking methods were applied to understand the structural features responsible for the affinity of the ligands in the binding of S. aureus DNA gyrase. Drug likeness and ADME analysis applied in this series of new proposed compounds, have shown that the five lead molecules would have the potential to be effective drugs and could be used as a starting point for designing compounds against Staphylococcus aureus.
A New and Ecological Method to Quantify Vancomycin in Pharmaceutical Product by Infrared Spectrometry
Authors: Nascimento Patrícia Aleixa do , Kogawa Ana Carolina , Salgado Hérida Regina Nunes
Published: June 2021

Vancomycin, an antimicrobial, does not present quantitative method by infrared spectrometry in the literature for the evaluation of a pharmaceutical product. This technique is considered a clean alternative because in the main, there is no solvent involved and the generation of waste is reduced. So, the aim of this study was to develop and validate a new, ecological, low cost and fast method by infrared spectrometry using KBr and band between 1450–1375 cm–1. It was linear in the range of 1.0–2.0 mg/150 mg, with a correlation coefficient of 0.9994. Selective when the spectra of vancomycin reference and sample were compared. Precise by repeatability (2.29%) and intermediate precision (3.12%). Accurate with average recovery of 99.37% and robust when strength and compression time of the pellets and KBr brand were varied. Considering all the methods found in literature, there is not one using infrared spectrometry for quantitative purpose, so the method developed and validated could be considered an innovation and clean alternative. This is due to the fact that it is fast, easy to handle, low cost, and non-toxic as well as generating minimal waste. The method can be applied in the routine analysis of vancomycin dosage form and is an important option for the current and sustainable pharmaceutical analysis.
Efficient and Facile Synthesis of Chromenopyrano[2,3-b] pyridine Derivatives Catalyzed by Sodium Carbonate
Authors: Keshavarz Raziyeh , Farahi Mahnaz , Karami Bahador
Published: June 2021

In this research, a number of new and known chromenopyrano[2,3-b]pyridine derivatives have been prepared. Initially, according to the reported procedure, pyrano[2,3-c]chromene derivatives were synthesized by the reaction between 4-hydroxycoumarin, aromatic aldehydes and malononitrile using silica sodium carbonate (SSC) as the catalyst. Next, the prepared pyrano[2,3-c]chromenes were reacted by dimethyl acetylenedicarboxylate (DMAD) or cyclohexanone in the presence of sodium carbonate to produce chromenopyrano[2,3-b]pyridine derivatives. The presented protocol avoids the use of expensive catalysts and gives useful potentially bioactive heterocycles in excellent to high yields.
Effect of the Exchanged Cation in an Algerian Montmorillonite Used as a Heterogeneous Catalyst for Biginelli Reaction
Authors: Belferdi Fatiha , Bouremmad Farida , Shawuti Shalima , Gulgun Mehmet Ali
Published: June 2021

In this work, an Algerian montmorillonite (Mt) is exchanged by different cations from the transition metals family, namely: Cu2+, Ni2+, Cr3+, Co2+, Fe2+ and Fe3+, it is used as a heterogeneous catalyst for Biginelli reaction. The exchanged cations are known for their catalytic properties in homogeneous catalysis. The main purpose is to study the effect of the exchanged cations on the yield and the kinetics of the reaction. The characterization of montmorillonite was carried out by XRD, which allows us to follow the evolution of the basal spacing d001 as a function of the exchanged cation and to show that the exchange operation has not altered the montmorillonite structure. The cation exchange capacity (CEC) is determined by the titration of the exchanged cation by atomic absorption. The product of the reaction is characterized by NMR, IR and by the determination of the melting point. In addition, the importance of the introduction order of the reagents into the reaction medium has been demonstrated on the yield and the kinetics. Finally, the obtained results show that the exchanged montmorillonite is competitive with other costly heterogeneous and homogeneous catalysts.
Methylene Blue Dye Removal from Aqueous Media Using Activated Carbon Prepared by Lotus Leaves: Kinetic, Equilibrium and Thermodynamic Study
Authors: Salahshour Roya , Shanbedi Mehdi , Esmaeili Hossein
Published: June 2021

In the present work, methylene blue was eliminated from aqueous solution using activated carbon prepared by lotus leaves. To perform the experiments, batch method was applied. Also, several analyses such as SEM, FTIR, EDAX and BET were done to determine the surface properties of the activated carbon. The results showed that the maximum sorption efficiency of 97.59% was obtained in initial dye concentration of 10 mg/L, pH of 9, adsorbent dosage of 4 g/L, temperature of 25 °C, contact time of 60 min and mixture speed of 400 rpm. Furthermore, the maximum adsorption capacity was determined 80 mg/g, which was a significant value. The experimental data was analyzed using pseudo-first order, pseudo-second order and intra-particle diffusion kinetic models, which the results showed that the pseudo-second order kinetic model could better describe the kinetic behavior of the sorption process. Also, the constant rate of the pseudo-second order kinetic model was obtained in the range of 0.0218–0.0345 g/mg.min. Moreover, the adsorption equilibrium was well described using Freundlich isotherm model. Furthermore, the thermodynamic studies indicated that the sorption process of methylene blue dye using the activated carbon was spontaneous and exothermic.
Plant-associated microbiome sampling protocol for field work v1
Authors: Ettinger Cassie , LaForgia Marina
Published: June 2021

This protocol details sampling of plant-associated microbiomes from plant communities in field plots.
DNA Library Prep for BGISEQ-500/MGISEQ-2000/DNBSEQ-G400/MGISEQ-200/DNBSEQ-G50 v1
Authors: Zhang Hongfang
Published: June 2021

This DNA library prep protocol is specifically designed for WGS library construction for MGI highthroughput sequencing platforms. It's applicable for samples from all common animals, plants, fungi bacteria, etc., including human, mice, rice, Arabidopsis, yeast, E. coli, and Metagenomics samples.
Protoplast Isolation from Zymoseptoria tritici v1
Authors: Khan Haseena , Mcdonald Megan , Solomon Peter
Published: June 2021

This is a basic protocol for protoplasting the fungal pathogen Zymoseptoria tritici