bluuebunny/crossref_metadata_2025 huggingface dataset:
Investigation of rs8106922 and rs157580 of TOMM40 Gene in In-dividuals with Late-Onset Alzheimer’s Disease in Iran
Authors: Hajilou Rana , Farhud Dariush D. , Zarif-Yeganeh Marjan
Published: March 2024

Background: We aimed to investigate two polymorphisms, rs8106922 and rs157580 of TOMM40 in Alzheimer's disease (AD).
Methods: In the present case-control research, we collected blood samples from 117 AD patients and 130 controls from Alzheimer's Hospital, residents of Tehran, Iran during the winter 2020 to autumn 2022. Following extraction of DNA, Genotyping of TOMM40 polymorphisms rs8106922 and rs157580 were examined by sequencing and ARMS/PCR approaches. We compared distributions of genotypes in both patient and healthy groups using the Chi-Square test.
Results: Regarding rs157580, a statistically significant difference was observed in the GA genotype frequency between patient and healthy groups, in both univariate and multivariate modes with these results that have come respectively, and it can be regarded as a protection factor P<0.05).. No significant difference was observed in the frequency of A and G alleles between patient and healthy groups. Besides, concerning rs8106922, the AG genotype frequency in research groups in both univariate and multivariate cases, with these results that have come respectively was significantly different (P=0.003) & (P=0.009). Regarding GG genotype, a statistically significant difference was observed between the patient and healthy groups in both univariate and multivariate cases, respectively (P=0.419) & (P=0.425). Significant differences were observed in the G allele frequency for rs8106922 in the healthy and patient groups (P=0.007), it can be regarded as a potential protective factor.
Conclusion: It is possible to consider the TOMM40 gene as one of the potential genes concerning Alzheimer's disease.
The Trend of Years of Life Lost due to Gastrointestinal Cancers in Fars (Iran) 2004-2019
Authors: Azarbakhsh Habibollah , Dehghani Seyed Sina , Hassanzadeh Jafar , Hassani Amir Hossein , Janfada Maryam , Mirahmadizadeh Alireza
Published: March 2024

Background: Gastrointestinal cancers can cause major health problems globally since their burden is increasing in many countries. We aimed to investigate the trend of years of life lost due to gastrointestinal cancers in Fars Province, southern Iran during the 2004-2019.                                    
Methods: In this cross-sectional survey study, we obtained the information regarding all deaths due to gastrointestinal cancers in Fars Province from the electronic population-based death registration system (EDRS). Years of Life Lost (YLL) was calculated using the YLL template of 2015 by the WHO. To examine the trend for different years, join point regression based on the log-linear model was used. Joinpoint regression analysis describes changing trends over successive periods of time and the increasing or decreasing rate within each period.  
Results: During the years of 2004-2019, 9742 deaths due to gastrointestinal cancers occurred in Fars Province. 6013 (61.72%) cases were male and 3729 (38.28%) cases were female (Male / Female Sex Ratio: 1.61). Overall, 4152 cases (42.63%) were due to gastric cancer and 2112 cases (21.68%) were due to liver cancer. Total years of life lost due to premature death from gastrointestinal cancers during the 16-year study period was 73565 yr (2.33 per 1000 persons) in men, 52766 yr (1.71 per 1000 persons) in women, and 126331 yr (2.02 per 1000 persons) in both sexes.                                                                                                                                      
Conclusion: Among all cancers, the highest mortality rates in both sexes belong to gastric cancer. This study showed the trend of YLL rate of malignant neoplasms of liver and intrahepatic bile ducts, esophagus, oral cavity, and colon cancer were increasing in both sexes, however, the trend of YLL rate for malignant neoplasms of the small intestine was decreasing in both sexes. Variation of GI cancers patterns and trends around the Fars Province indicated that a more comprehensive control plan is needed to control these variations.
Analysis of the Frequency, Antibiotic Susceptibility, and Related Genes among Foodborne Pathogenic Bacteria Isolated from Hospital Refrigerators in Tehran, Iran
Authors: Soltanzadeh Elham , Hosseini Hedayat Hosseini , Boroumand Mohammadali , Motallebi Abbasali
Published: March 2024

Background: Hospital refrigerators as essential food storage can be important source of food contamination. We aimed to investigate the frequency and antibiotic susceptibility of the pathogenic bacteria in three hospital refrigerators in Tehran.
Methods: This study was performed on 254 samples, collected from 60 refrigerators of the various wards of three hospitals, A, B, and C, in Tehran, Iran from 2020 to 2021. Following isolation and identification of isolates, the antibiotic susceptibility pattern was determined. PCR-based assays were used to screen the presence of antibiotic resistance genes of resistant isolates.
Results: From 254 collected samples, 236 samples (92.9%) were contaminated. Most strains were isolated from refrigerators with poorly cleaned, temperatures above 8 °C in non-critical wards. Most bacteria belonging to Enterobacteriaceae (68.8%), followed by Staphylococcus (11.9%), and Enterococcus (10.6%), while the frequency of non-Enterobacteriaceae isolates was 8.9%. The highest antibiotic resistant bacteria were in extended spectrum beta-lactamase (ESBL) 9.7%, vancomycin-resistant enterococci (VRE) 5.3%, methicillin-resistant S. epidermidis (MRSE) 0.4%, and methicillin-resistant S. aureus (MRSA) 0.4%, respectively. The blaOXA-48, blaCTX, and bclaTEM genes were found only in 10% of Enterobacteriaceae isolates. The blaOXA-51 gene was found in all non-Enterobacteriaceae isolates. The vanA and mecA genes were detected in antibiotic-resistant Enterococcus and Staphylococcus.
Conclusion: Our findings suggests major concern about cross-contamination and the emergence of antibiotic-resistant isolates as a potential health threat with hospital refrigerators origin. More attention to hospital refrigerators cleaning is necessary to prevent foodborne diseases and nosocomial infections.
Key Indicators for Monitoring the Efficiency of Iranian Health System: A Synthesized Design Study
Authors: Jaafaripooyan Ebrahim , Daroudi Rajabali , Damiri Soheila , Mousavi Abdoreza , Mohamadi Efat , Takian Amirhossein , Olyaeemanesh Alireza
Published: March 2024

Background: A significant share of medical care, primary health care, and health-related education and research in Iran is provided by the Ministry of Health and its affiliated universities of medical sciences. We aimed to identify a set of key metrics for monitoring their efficiency in the four areas of medical care, primary health care, education and research.
Methods: A combination of scoping review, expert panel and Delphi method was used. First, the relevant keywords were searched in the appropriate databases between 2000 and 2020. The final extracted indicators then reviewed, reduced and refined through the expert panel meetings. The last metrics were established following a three-stage Delphi study.
Results: Out of 2327 studies, 155 were selected following the different screening stages of scoping review. After summarizing and refining the indicators via several expert panel meetings and the Delphi method, a total of 36 key indicators were considered appropriate for measuring efficiency of the health system, 23 of which were for the sub-systems of public health (4 indicators), medical services (10 indicators), education (4 indicators) and research (5 indicators) and 13 indicators for the whole system efficiency.
Conclusion: The set of indicators presented representing both the technical and allocative efficiency, might be a reliable basis for designing information systems and management dashboards for periodic monitoring of health system efficiency at national, regional and local levels.
Gene Expression Patterns of Colorectal Cancer Stem Cells Following Ibuprofen and Hyperthermia Treatment
Authors: Valibeigi Behnaz , Behzad-Behbahani Abbas , Forouzanfar Mohsen , Zarghampoor Farzaneh , Jaafarinia Mojtaba
Published: March 2024

Background: Cancer stem cells (CSCs) substantially influence the development of colorectal cancer (CRC), metastasis, relapse, and resistance to therapy. Ibuprofen and hyperthermia can be effective in the treatment of cancer. Herein, we evaluated the effects of hyperthermia and ibuprofen on the isolated-CSCs of CRC.
Methods: This experimental study was conducted between Sep 2020 and Jan 2022 at the Department of Pathology, School of Medicine, Shiraz University of Medical Sciences, Iran. A non-adhesive culture system was used to isolate CSCs from HT-29 cells. To confirm the stemness nature of isolated-CSCs, the expression of stemness genes and protein markers was evaluated by quantitative Real-time PCR (qRT-PCR) and flow cytometry assay. The isolated-CSCs were treated with hyperthermia and ibuprofen. The cell viability was determined by MTT assay and trypan blue staining. The expression of stemness, proliferation, Wnt signaling pathway and apoptosis genes was assessed by qRT-PCR.
Results: CSCs were isolated within 14 days. The expression of CD-133 marker and OCT3/4, C-MYC, KLF4, and NANOG genes in isolated-CSCs was higher than HT-29 cells (P<0.05). Cell viability of treated-CSCs were considerably reduced (P<0.05). Hperthermia reduced the expression of OCT3/4, NANOG, PCNA, WNT1 and CTNNB1 genes and increased the expression of P53, BAX, and KLF4 genes (P<0.05). Ibuprofen decreased the expression of OCT3/4, BCL2, NANOG, PCNA, WNT1, and CTNNB1 genes and increased the expression of P53, BAX, and KLF4 genes in treated-CSCs (P<0.05).
Conclusion: Hyperthermia and ibuprofen treatment demonstrate an inhibitory effect on colorectal CSCs. However, using combination therapy is remaining to be tested.
Association between Neck Circumference and Thyroid Disease: Findings of a Nationwide Cross-Sectional Study in Korea
Authors: Park So-Jung , Hwang In Cheol , Ahn Hong Yup
Published: March 2024

Background: There were contradictory reports about the relationship between neck circumference (NC) and thyroid status. This study aimed to compare the NCs of Korean adults with or without thyroid disease.
Methods: The data of 8,198 subjects (aged 40–80 yr) that participated in the 2019-2020 Korean National Health and Nutrition Examination Survey were subjected to analysis. NCs were measured by trained staff to an accuracy of ±0.1 cm with a tape measure. Multiple logistic models were used to assess the prevalence of thyroid disease by NC level among men and pre- and postmenopausal women.
Results: Approximately 5% of subjects had a history of thyroid disease. In contrast to men and postmenopausal women, premenopausal women with a larger NC had a significantly higher prevalence of thyroid disease (P-value=0.025).
Conclusion: A large NC is significantly associated with thyroid disease among premenopausal Korean women.
Application of Rodenticides for the Control of Zoonotic Cutaneous Leishmaniasis in Iran: A Systematic Review of the Literature
Authors: Afshar Abbas Aghaei , Gorouhi Mohammad Amin , Sharifi Iraj , Yousefi Saideh , Shirani-Bidabadi Leila , Faraji Maryam , Jangipour Afshar Parya , Alizadeh Ismaeil
Published: March 2024

Introduction: Rodent control programs have a long history of controlling zoonotic cutaneous leishmaniasis (ZCL) in Iran. The present systematic review reports the effect of rodenticides in reducing ZCL in Iran. 
Materials and Methods: Various electronic databases were explored for reliable research using appropriate keywords between January 1970 and September 2023. Relevant studies were included based on the inclusion criteria. All articles identified from the systematic search were added into Endnote X9 (Clarivate Analytics) and duplicate articles were removed. This study followed standard procedures for systematic reviews and reported results according to systematic reviews guidelines.
Results: Overall, 637 documents were identified after screening based on the PRISMA checklist, and finally, 13 papers were included in this systematic review. The findings indicated that most of studies used zinc phosphide (2.5%) and Klerat® mixed with wheat grains in rodents control programs in Iran. The results showed that rodent control programs were implemented in five provinces of Iran, including Esfahan, Yazd, Semana, Golestan, Kermanshah, and Fars, with the highest number of studies in Esfahan province. According to results, the incidence rate of ZCL significantly reduced after rodenticide implementation.
Conclusion: This review study provides a better understanding of rodent control programs trends as a promising and practical approach to reducing ZCL incidence in Iran over the past 50 years and can serve as a reference for planning future control and research programs.
Assessing the Rate of Recyclable Plastic Wastes and Recycling Economic Value in Hospitals of Yazd in 2022
Authors: Bagheri Masoumeh , Mehrizi Ehsan Abouee , Koupal Roghayyeh , Mokhtari Mehdi
Published: March 2024

Introduction: Special and infectious wastes are the most significant wastes generated in hospitals, health centers, and similar facilities. Reducing and recycling such wastes at the source pose significant challenges to waste management. Therefore, this study assesses the components of healthcare waste in terms of their recyclability, emphasizing different types of plastic.
Materials and Methods: Data collection involved sampling normal and infectious waste in selected hospitals over three months using monthly checklists. The total waste generated in these hospitals was analyzed on a daily basis. Moreover, the average microbial load of infectious waste was determined through microbial strip tests and biological tests following patient companion. Tests were performed with the acceptable performance of safe hospital devices with the destruction of microorganisms.
Results: Average waste composition in the selected hospitals included 65-70% general waste and 30-35% infectious waste. The most common generated infectious waste was polyethylene (PE) sets (800 kg/month), while the predominant general waste was nylon bags for polyethylene terephthalate (PETE) packaging (520 kg/month). Hospital 1 had the highest per capita production of recyclable waste, generating 7,900 kg and 2,550 kg of normal and infectious waste per month, respectively. The total revenue generated from selling normal and infectious plastic waste was 1.4 and 0.2, respectively.
Conclusion: The mixing of waste can be prevented by properly segregating normal and infectious waste and adequate staff training. Given the escalating disposal costs of health-care waste (HCW) and the shrinking space in landfills, efforts to minimize waste generation are crucial for effective recycling and reuse processes.
Teacher Perceptions in Implementing Religious Character Education in Elementary Schools
Authors: Rachmadtullah Reza , Pramujiono Agung , Rasmitadila Rasmitadila , Syamsi Atikah
Published: March 2024

Religiosity is the attitude and behavior of a person who is obedient in carrying out the teachings of the religion they adhere to. It is inherent in the person, fostering tolerance and harmony with followers of other religions. It serves as a reflection of their obedience to the teachings of the religion they follow. This research aims to determine how teachers perceive implementing religious character education in elementary schools. This type of research employs a descriptive qualitative method. The results of this research indicate the implementation of religious character education in elementary schools, achieved by integrating religious values into the school curriculum. In addition, schools conduct spiritual activities, and teachers serve as role models by exemplifying positive behaviors such as doing good deeds, helping others, maintaining discipline, and engaging in religious activities.
Keywords: character education, religious, elementary school
Implicature in Online Comics of ``Komik Grontol" Instagram: A Pragmatics Study
Authors: Yusuf Sidiq Budiawan Raden , Fitrotul Mualafina Rawinda , Ulfiyani Siti , Mukhlis Mukhlis
Published: March 2024

Language on social media frequently exploits various objectives through its implicatures. One of the more intriguing applications of this technique is the use of language implicatures in digital comics on the Instagram account “Komik Grontol”. The purpose of this study is to describe the form and function of implicature used in Online Comics of “Komik Grontol” Instagram. This research employed a descriptive-qualitative approach. The data source in this research is the Instagram social media account of “Komik Grontol”. The data taken from the source consists of written speech in humor posts on the “Komik Grontol” Instagram, which contains implicature. The results of the data analysis show two forms of implicature: conventional implicature and conversational implicature. Conversational implicature dominates with 24 instances, while the remaining is a form of conventional implicature with four instances. Furthermore, the data from “Komik Grontol” Instagram posts revealed five functions: representative (6 instances), directive (7 instances), expressive (12 instances), commissive (2 instances), and isbati (1 instance). This online comic uses implausibility to satirize current social events.
Keywords: implicature, Instagram; komik grontol, pragmatics
Various Factors that Influence the Successful Implementation of School Digitalization Policies
Authors: Nurkolis Nurkolis , Muhdi Muhdi , Maryant Maryanto , Kusumaningsih Widya
Published: March 2024

School digitalization in Indonesia has been widely implemented in line with the 2020/2021 education transformation policy. Various factors are thought to support the success of digitizing the learning process, school management, and how people work in schools. This research aims to determine various factors that positively influence the successful implementation of school digitalization at Junior High Schools (SMP) and Madrasah Tsanawiyah (MTs). This research uses a quantitative cause-and-effect approach with a questionnaire distributed online. The research was conducted in semester 1 of 2023 with 1088 respondents. Data processing was done using non-parametric Mann-Whitney and Kruskal-Wallis statistics for normal distribution. The research results that consistently show a positive and significant influence are differences in regions and respondent positions. Factors not influencing school digitalization are gender and type of school. Inconsistently influential factors are the respondent’s age, type of school transformation intervention, and school status. Regional differences, which indicate differences in school digitalization policies by local education leaders, positively influence the success of school digitalization. Likewise, the stronger a person’s position in a school in pushing policy, the greater the influence on the quality of school digitalization. Thus, the two factors, namely a person’s position and regional differences, indicating differences in leadership, are recommended to be strengthened to increase the success of implementing school digitalization policies.
Keywords: educational transformation, digitalization of learning’ digitalization of management, digitalization of ways of working
Strategy for Preventing Potential Conflicts in the Establishment of Religious Minority Houses of Worship in the City of Semarang
Authors: Suneki Sri , Yunus Mahmud , . Haryono
Published: March 2024

Semarang City is a city that has social, religious, and cultural diversity. There is currently potential for conflict in several areas of Semarang City due to the rejection of the establishment of religious minority places of worship. The purpose of this research is to reveal the potential causes of conflicts over the construction of houses of worship of minority religions and to find appropriate strategies to prevent conflicts from occurring due to the construction of houses of worship of the majority religion. This qualitative research adopted a case study approach with data collection techniques of observation, documentation, and in-depth interviews with key informants and supporting informants. The results of this study indicate that in the Tlogosari and Sendangmulyo areas there is the potential for conflicts to occur against the background of the construction of a church house of worship, the root cause of this potential conflict is due to the refusal of permits. The conflict prevention strategy is to provide social education to the community regarding pluralism education with a social approach that is carried out with synergy between the government and the community. The implications of this research can be used as a reference by the Semarang City Government in preventing conflicts due to the establishment of religious minority places of worship.
Keywords: conflict prevention; conflict potential; social conflict; religious conflict
Development of An Agribusiness Textbook on Raising Giant Prawns (Macrobrachium Rosenbergii) in Environmentally Friendly Biofloc-Aquaponics Ponds''
Authors: Rita Sulistya Dewi Endah , Susatyo Nugroho Ary , Ulfah Maria
Published: March 2024

The agribusiness textbook on “rearing giant prawns (Macrobrachium rosenbergii) in environmentally friendly biofloc-aquaponics Ponds” was prepared as a result of research and has been published to help increase students’ understanding of agribusiness courses in the Biology Education Study Program, Faculty of Mathematics and Natural Sciences Education and Information Technology (FPMIPATI), PGRI University Semarang. The research method used is R and D. The design of the textbook that was developed aims to attract students’ attention in learning, making it easier for lecturers to master the teaching and learning process. Therefore, valid teaching materials are needed. The results of the research show that validation by validators resulted in the validation of teaching material media of 97.5% and validation of teaching material of 96.67% so it was declared in the very good category and suitable for use in learning. This textbook can make it easier for students to understand Agribusiness material, especially about raising giant prawns (Macrobrachium rosenbergii) in environmentally friendly biofloc-aquaponics ponds. Furthermore, the publication of this book is also hoped to motivate lecturers to continue writing according to their respective expertise to add to the scientific knowledge at PGRI University Semarang.
Keywords: textbook, agribusiness, biofloc-aquaponics
Development of Social Emotional Based Book Activity: Product Validity
Authors: Dwijayanti Ida , Andri Nugroho Aryo , Esti Utami Rizky , Khasanah Ismatul
Published: March 2024

Indonesia is in the fifth highest position out of 78 countries where most of the students experience bullying. The Ministry of Education and Culture has issued various policies intended to overcome this problem, one of which is establishing the Pancasila student profile as the vision of Indonesian education. To support this, educators are needed who have high qualifications, competence, and dedication in carrying out their professional duties. Based on extracting information from preliminary research that has been carried out by researchers, the main problem faced by early childhood teachers is the lack of references regarding activities that can be carried out by early childhood teachers to realize the themes set by the Ministry in realizing an integrated Pancasila student profile, teaching media, and evaluation tools. This research aims to produce an activity book for teachers based on social emotional learning, which has been proven to be practical and effective in increasing the competency of early childhood postal teachers, and to produce an activity book for students based on social emotional learning which has an impact on the growth and development of Pancasila student profiles for PAUD students. The data collection and analysis methods used in the first year were documentation methods to obtain data on teaching materials before they were developed, questionnaires to obtain expert validation data, and readability by partner teachers. All data will be analyzed descriptively.
Keywords: teacher activity book, student activity book, teacher competencies, Pancasila student profile
Identifying and prioritizing measures to reduce the failure of the implementation of health system policies based on the technique of analyzing failure states and their effects and fuzzy TOPSIS
Authors: MS Abolhasani , M Ziaadini , MA Nik Bakhsh
Published: March 2024

Inroduction: policy implementation is the actions that are taken by government or private sector individuals with the aim of realizing the goals of the policy.Many experts have listed many factors in explaining the factors affecting policy implementation and the problems of policy implementation, and most of them believe that the problems of policy implementation are different with the conditions of each society. Several measures lead to the reduction of failure in the implementation of health system policies/ The purpose of this research is to identify and rank these factors.
Materials and methods: This research was applied and in terms of strategy, it was a survey. The research community consisted of 21 health managers of the country, who were selected through non-random and purposeful sampling. The tools of data collection are interviews and questionnaires, and the FMEA technique and the combined approach of AHP and Fuzzy TOPSIS were used to analyze the data.
Results: The results of the research showed that the experts have a total of 10 dimensions in the spectrum of failure reduction measures, including cultural factors, communication, structure, implementation method, management, support, manpower.policy implementers, society, policy formulation and environment and 50 components. They proposed important measures effective in reducing the failure of the implementation of health system policies.
Conclusion: What was stated in this research as the measures to reduce the failure in the implementation of these policies will help the managers and actors of the health system policy field to prevent the occurrence of problems in the path of successful implementation of the health system policies by knowing the factors that reduce the failure of the implementation of the health system policies. get healthy.
Investigating the effect of posture correction on the amount of musculoskeletal pain of patient carriers in Bahoner Hospital, Kerman
Authors: N Eskandari nasab , AH Mehrparvar , R Soltani , M Eskandari nasab , M Montazeri , G Afsharipour , E Hajipour , N SHahsavari , A Hajalizadeh
Published: March 2024

Introduction: Due to the obviousness of musculoskeletal disorders in health workers, especially patient carriers, we felt it necessary to check the amount of musculoskeletal pain in these workers by correcting the posture. 
Mateials and Methods:The study is semi-experimental. First, a demographic questionnaire, a self-made questionnaire on the level of awareness and a Nordic questionnaire along with a numerical rating scale to measure the amount of pain related to musculoskeletal disorders were completed for all participants. Then, theoretical and practical interventions were carried out in order to correct posture using occupational medicine, ergonomics, and sports specialists, and again one month and six months later, questionnaires were completed and data were collected. At the end, data analysis was done with SPSS version 24 software.
Results: Descriptive statistics show that interventions aimed at correcting posture reduce the average scores of pain for different body parts of patient carriers. And the most obvious musculoskeletal disorder is back pain.
Statistical analysis showed that comparing the average score of back pain (p=0.000), neck (p=0.014), shoulder (p=0.006), knee (p=0.006) and leg (p=0.016) in patient carriers before There is a significant difference between postural correction and six months later.
However, comparing the average pain score of elbow (p=0.18), wrist (p=0.06), back (p=0.3) and thigh (p=0.08) at the end of six months after correcting the posture, no significant difference was observed.
Conclusion: It seems that correcting the posture while carrying and moving the patient with the help of occupational medicine, ergonomics and sports specialists can reduce musculoskeletal pain in medical workers, especially patient carriers. It was also seen that correcting posture has the fastest and greatest effect on reducing back, neck, shoulder, knee and leg pain.
Covid-19 Sürecinde Gebelerin Anksiyete, Durumluk ve Sürekli Kaygı Düzeylerinin Belirlenmesi
Authors: Kınacı Hatice , Onur Suzan
Published: March 2024

Amaç: Gebelik dönemi, kadınlarda ruh sağlığı rahatsızlıklarının gelişmesi ve var olan hastalıkların artış göstermesinde risk faktörü olarak görülmektedir. COVID-19 salgın sürecinde özellikle gebe kadınların ruhsal yönden daha çok etkilenebilecekleri düşünüldüğünden; bu süreçte gerçekleştirilen çalışma, gebe kadınların gebelik süresince algılanan anksiyete ve kaygı düzeylerinin belirlenmesi ve buna uygun önerilerin geliştirilmesi amacıyla yapılmıştır.

Gereç ve Yöntemler: Gerekli etik kurul ve kurum izinleri alındıktan sonra başlanan tanımlayıcı tipteki bu çalışmaya, Ankara Eğitim ve Araştırma Hastanesi Kadın Doğum Polikliniğine başvuran yalnızca gebelik tanılı 402 gebe dahil edildi. İstatistiksel analizler için SPSS 20.0 paket programı; veri toplama araçları olarak kişisel bilgi formu, BECK Anksiyete Ölçeği, Durumluk Kaygı Ölçeği ve Sürekli Kaygı Ölçeği kullanıldı. BECK Anksiyete Ölçeğinden alınan toplam puan bireyin yaşadığı anksiyetenin şiddetini göstermektedir. 0-7 puan minimal düzeyde, 8-15 puan hafif düzeyde, 16-25 puan orta düzeyde ve 26-63 puan şiddetli düzeyde anksiyeteye sahip olarak kabul edildi. Durumluk Kaygı Ölçeği ve Sürekli Kaygı Ölçeği ortalama puanları için; 0-19 puan ‘Anksiyete yok’, 20-39 puan ‘Hafif Anksiyete’, 40-59 puan ‘Orta Düzeyde Anksiyete’, 60-79 puan ‘Ağır Düzeyde Anksiyete’, 80 ve üstü puan ise ‘Panik’ olarak değerlendirildi.

Bulgular: Katılımcıların yaş ortalamasının 26,04±4,84, BECK Anksiyete Ölçeği puan ortalamasının 16,94±11,22, Durumluk Kaygı Ölçeği puan ortalamasının 41,83±16,23, Sürekli Kaygı Ölçeği puan ortalamasının ise 44,20±13,07 olduğu tespit edilmiştir. Gebelerin BECK Anksiyete Ölçeği puanlarına göre; %28,4’ünün hafif düzeyde, %24,9’unun orta düzeyde, %24,1’inin şiddetli düzeyde anksiyetesinin olduğu ve %22,6’sının ise anksiyetesinin olmadığı belirlenmiştir.

Sonuç: Bu çalışma, COVID-19 sürecinin, gebelik döneminde görülen anksiyete ve kaygı düzeyi üzerine anlamlı bir etkisinin olmadığını göstermiştir ve COVID-19 sürecinde gebe olan kadınların kaygı düzeylerinde anlamlı bir fark bulunmamıştır.
Respiratuar sinsityal virüse bağlı alt solunum yolu enfeksiyonu nedeniyle hastanede yatmış çocukların uzun dönem prognozunun belirlenmesi
Authors: Çolak Mustafa , Şirin Seda , Uzuner Nevin
Published: March 2024

Amaç: Solunum enfeksiyonları, özellikle Respiratuvar Sinsityal Virüs (RSV), küresel olarak genç çocukları önemli ölçüde etkilemekte, ölümlere ve uzun süreli solunum sorunlarına neden olmaktadır. Erken yaşta ciddi enfeksiyonlar, yetişkinlikte astım ve bozulmuş akciğer fonksiyonu gibi kronik durumlara yol açabilir. Bu çalışma, RSV kaynaklı alt solunum yolu enfeksiyonu geçiren çocukların uzun vadeli sağlık sonuçlarını belirlemeyi amaçlamaktadır.

Gereç ve Yöntemler: Çocuk Sağlığı ve Hastalıkları Kliniği'nde retrospektif gözlemsel bir araştırma olarak yapılan bu çalışmada, RSV kaynaklı alt solunum yolu enfeksiyonları nedeniyle Ocak 2007 ile Aralık 2014 yılları arasında tedavi edilen 1 ay ile 5 yaş arası çocuklar incelenmiştir. Hastaların aileleri telefonla ulaşılarak bilgilendirilmiş ve sözlü onamları alınmıştır. Ardından, bu ailelerle RSV enfeksiyonundan sonraki döneme odaklanan anketler yapılmıştır. Hastaneye yatırılma risk faktörlerini belirlemek için lojistik regresyon analizi kullanılmış, istatistiksel anlamlılık p
Optimalno motivacijsko učno okolje v glasbenih šolah – preplet vizij učencev, njihovih staršev, učiteljev in ravnateljev
Authors: Habe Katarina , Laure Maruša , Kavčič Pucihar Ana
Published: March 2024

Učna motivacija je eden najbolj zahtevnih vidikov učenja glasbenega inštrumenta. Pomemben dejavnik v učenčevi motivaciji za igranje inštrumenta predstavlja socialno okolje, torej starši in učitelji. Učno motivacijo naj bi v veliki meri usmerjale učenčeve zaznave učnega okolja, ki vplivajo na kakovost učenja prek zavzetosti učencev. Namen naše raziskave je bil osvetliti vizije glavnih socialnih akterjev v glasbenih šolah in preplet oziroma razhajanja v njihovih pogledih na optimalno motivacijsko učno okolje glasbenošolskih ustanov. S pomočjo skupinskega intervjuja v fokusnih skupinah učencev, njihovih staršev, učiteljev inštrumenta in nauka o glasbi ter ravnateljev smo ugotovili, da obstajajo štirje glavni tematski sklopi: odnosne spremembe, didaktične spremembe, ohranjanje statusa quo in sistemske spremembe. Najbolj izrazite so bile didaktične in odnosne spremembe, ki so se pojavljale pri vseh socialnih deležnikih, razen pri ravnateljih. Vsi socialni deležniki so navajali sistemske spremembe kot korak k ustvarjanju optimalnega motivacijskega učnega okolja. Za ohranjanje statusa quo so se najbolj zavzemali ravnatelji, medtem ko so si učenci, ki so izobraževanje predčasno zaključili, in njihovi starši želeli sprememb. V skladu s teorijo samodoločanja je bila močno izpostavljena potreba po povezanosti.
Izzivi medpredmetnega načrtovanja glasbene umetnosti
Authors: Zalar Konstanca , Sicherl Kafol Barbara
Published: March 2024

V poglavju opisujemo medpredmetno povezovanje kot celostni didaktični pristop, ki ga opredeljujemo s horizontalnim in z vertikalnim povezovanjem znanja, vsebin in učnih spretnosti. V raziskavi smo z deskriptivno metodo pedagoškega raziskovanja preučevali, kako bodoči razredni učitelji načrtujejo medpredmetno povezovanje glasbene umetnosti z drugimi predmetnimi področji. V 186 učnih pripravah je bilo zastopanih 293 medpredmetnih ciljev, ki so bili v veliki meri (75,43 %) načrtovani na procesno-ciljni ravni, manj na vsebinsko-konceptualni ravni (21,16 %) in zanemarljivo malo na vsebinsko-snovni ravni (3,41 %). Skozi analizo medpredmetnih povezav glasbene umetnosti z drugimi predmetnimi področji se je pokazalo, da prevladujejo povezave s slovenščino, ki ji sledijo povezave s športom. Povezave z drugimi umetnostnimi področji niso bile zastopane, z izjemo redkih povezav z likovno umetnostjo (2,93 %). Izsledki raziskave kažejo, da so medpredmetne povezave skladno s sodobno procesno-ciljno kurikularno strategijo ustrezno zastopane na prevladujoči procesno-ciljni ravni; pri tem so pomanjkljivo zastopane povezave glasbene umetnosti z drugimi umetnostnimi področji, kar usmerja v nadaljnje raziskave z vidika razlogov za navedeno stanje.
Estimation of Shelf Life and Development of Packaging Standards for Bulk Packaging of Orthodox Tea [Camellia sinensis (L.) Kuntze] for Export
Authors: Bhattacharjee Donal , Patriwar Pooja , Ravandale Vaishali , Bandekar S.H. , Das Bidhan , Guduri Babu Rao , Alam Tanweer
Published: March 2024

Background: Tea is a shelf-stable product in which respiration processes are suspended, but biochemical, microbial and other decomposition processes continues depending upon the storage conditions. Considering the present problems, a study was undertaken with the objective to develop bulk packaging of Orthodox tea by taking up testing of packaging materials, shelf life studies and laying out specifications for bulk packaging of tea for the export market. Methods: The tea samples were packed in ten different packaging materials and exposed to accelerated climatic conditions (38±1°C and 90±2% RH) for a period of four months. The experiment was laid out in completely randomized design and replicated thrice. Result: The moisture content of Orthodox tea was showed a gradual increase during the exposure period. Heavy metals, total ash content and tannin content were found in permissible limits. The sorption isotherm of Orthodox tea was characterized by a sigmoid shape curve. No damage to the packaging materials was observed during transport worthiness test. The maximum shelf life of 105 days was attained in sandwich bag and PP woven sack with LDPE-EVOH-LDPE liner and 4 ply Multiwall Paper Sack with two liners at accelerated conditions. Based on this, it was concluded that the maximum estimated storage life at 27±1°C and 65±2% RH was 315 days and the same can be achieved by sandwich bag and PP woven sack with LDPE-EVOH-LDPE liner and 4 ply Multiwall Paper Sack with 7 µ Aluminium Foil/poly liner and 12 µ MET PET/poly liner.
Extent of Extraneous Water and Detection of Various Adulterants in Raw Milk during Supply Chain and its Impacts on Milk Physical Characteristics
Authors: Abbas Sayed Zaheer , Khan Muhammad Naseem , Naqvi Anjum Zehra , Kaif Kashan , Kanwal Sidra , Khan Abdul Basit , Siddiqui Anila , Hussain Mazahir
Published: March 2024

Background: The study’s objective was to recognize the various adulterants and their effects on the physical characteristics of the raw milk available in the city. The milk dealers, especially in the developing countries usually involved in milk adulteration practices in order to increase their profit margins, which poses significant health hazards. Methods: A total of 189 samples of raw milk were gathered across Karachi’s five districts. Milk adulteration testing kit were employed for various adulterants detection and its physical impacts on milk was analyzed by the AOAC methods. Result: The milk samples from selling points had the highest levels of adulteration, followed by those from transportation cans and storage tanks at dairy farms. Chemical adulteration impact on milk pH and specific gravity was very prominent while extraneous water showed significant impact on milk specific gravity rather than its pH. Average pH and specific gravity values of milk sample collected from storage tanks at dairy farm were normal, while it was out of range in the milk samples collected from transportation cans and selling points. As indicated that at the dairy farms had very few milk adulteration activities, whereas milk samples being transported and sold in stores had the highest number of fraud attempts
Exploring numeracy teaching and learning by using ethnomathematics
Authors: Mukwambo Muzwa , Zulu Africa , Kayangula Manyando
Published: March 2024

The purpose of this study was to explore the impact that the cultural or everyday practices of ethnomathematics of a particular cultural group will have if they are used in teaching and learning of numeracy concepts related to geometrical shapes. It explored cultural practices, artefacts, written, verbal or visual communication messages reflecting mathematics in order to see how they could best eliminate the problems learners encounter in the acquisition of numeracy language. Data was generated using observations, brainstorming and interviews. Based on this research, the impact of using ethnomathematics in numeracy teaching and learning brings in innumerable benefits. These include promoting deep learning and allows teachers to maka use of prior knowledge in the classroom. This allows learners to recall and relate to the concepts learnt and employ them in their daily activities so that they do not to remain inert. Another impact of interest was the reclaiming of names of geometrical shapes from certain languages which currently teachers are not aware of as they are overlooked. For instance when geometrical shapes were first discussed using local terminology, it made more meaning than when taught using English used as a medium of teaching and learning in the research area.
Hubungan Pengetahuan terhadap Sikap dan Perilaku Penggunaan Antibiotik pada Mahasiswa Medis dan Kesehatan Universitas Jember
Authors: Wisudanti Desie Dwi , Setyaningrum Wiwied Hary , Efensi Erfan
Published: March 2024

Antibiotik merupakan obat yang penggunaannya harus berdasarkan resep dokter. Penggunaan antibiotik tanpa resep di masyarakat relatif tinggi. Penggunaan antibiotik yang tepat dipengaruhi oleh pengetahuan dan sikap dalam menggunakan antibiotik. Pengetahuan mengenai penggunaan antibiotik pada mahasiswa kesehatan dinilai mempunyai peran penting dalam sikap dan perilaku profesional dalam penggunaan antibiotik untuk menurunkan angka resistensi antibiotik. Penelitian ini bertujuan untuk mengetahui hubungan pengetahuan, sikap, dan perilaku penggunaan antibiotik pada mahasiswa medis dan kesehatan Universitas Jember serta mengetahui perbedaan pengetahuan, sikap, dan perilaku penggunaan antibiotik pada mahasiswa medis dan kesehatan Universitas Jember. Pengambilan sampel dalam penelitian ini menggunakan metode proportional stratified random sampling dengan menggunakan instrumen pengumpulan data kuesioner. Hasil penelitian menunjukkan bahwa tingkat pengetahuan, sikap, dan perilaku mahasiswa medis dan kesehatan Universitas Jember mengenai penggunaan antibiotik sebagian besar berada pada kategori baik. Terdapat hubungan antara pengetahuan, sikap, dan perilaku dalam penggunaan antibiotik (p<0,05), serta terdapat perbedaan pengetahuan dan perilaku penggunaan antibiotik pada mahasiswa medis dan kesehatan (p<0,05).
Liberal model and research model of university education as the institutional basis for intellectualizing society and saving the fundamental value of mental work
Authors:   National Academy of Sciences of Republic of Belarus, Kostyukevich Svetlana V.
Published: March 2024

This article provides a rationale for the fundamental value of mental work and, above all, complex mental work, the bearers of which are intellectuals and scientists. Definitions of the concepts of mental work, intellectual work, intellectuals, and intellectualization of society, liberal model of university education and research model of university education are given. The article proves that the classical university (represented by the liberal model and the research model) is the institutional basis to ensure an intellectualization of society and safekeeping a mental work value. It also proves that complex mental work (work of intellectuals and scientists) lies at the basis of scientific and technical development as a standard of modern society. And the article finally proves that the intellectualization of society is closely connected with scientific and technological development and, accordingly, with technological leadership.
“Open University”: Conceptualization and Schematization of University 3.0 from the perspective of a System-Thinking-Activity (STA) approach (Part 2)
Authors:   Kuban State Medical University of the Ministry of Healthcare of the Russian Federation, Yurganov Alexander A. , Svistun Olesya V. , Pidshmorga Yulia V.
Published: March 2024

The point is that after the destruction of the classical university, the essentially ‘closed’ ‘University of Excellence’ of B. Ridings took its place almost everywhere. The question is, what should replace it? Our task is to grasp schematically and conceptually the essence of University 3.0 as a real, in our opinion, alternative to the “closed” University of Excellence. To do this, we will rely on a System-Thinking-Activity approach (SMD-approach). Our leading hypothesis is that University 3.0 cannot be understood exclusively as an ‘Entrepreneurial University’ by B. Clark, where an environment has been created for the introduction of scientific innovations into life, but at the same time the idea of ‘autonomy of thinking’ as inherently non-utilitarian, the idea of Culture as the basis for nurturing the Personality of a person who, thanks to this should be ‘raised to the level of his time’ (Ortega-y-Gasset). It is Culture at the university that should become a meeting place for Science and Technology, Research and Business, and the university itself should become a means of cultural transformation (A. Auzan). And the questions are, what exactly does that mean? How exactly to achieve this? In this paper, we have tried to outline a general conceptual space for answering these questions, using a set of concepts and schemes of the System-Thinking-Activity methodology (SMD-methodology). The second part summarizes the findings of the study.
Generalization of the best educational practices in higher education (based on the results of a survey of finalists of the RANEPA Pedagogical Excellence Competition)
Authors:   National Economy and Public Administration under the President of the Russian Federation (RANEP), North-West Institute of management-branch, Vylkova Elena S.
Published: March 2024

Currently, there is a multifaceted transformation of higher education in terms of digitalization of the teaching and educational process, visualization of teaching, use of Internet resources, application packages, electronic library and reference systems, organization of group interaction among students and other aspects of the educational process in higher education. The purpose of this work is to identify trends in the use of various technologies and teaching methods in the higher education system, problems of their application and the formation of a basic list of resources and interactive teaching methods for implementation in universities of the Russian Federation to improve the quality of education and the effectiveness of the educational process. The achievement of this goal was carried out on the basis of summarizing the results of a survey of finalists of the RANEPA Pedagogical Excellence Competition in December 2023. Lists of the main resources of platforms for training, solving standard problems of communications and cooperation in the digital environment have been compiled; resources for storing and distributing educational and other materials; tools for searching, processing and visualizing information; resources for storing and distributing educational and other materials and other resources and tools for organizing the educational process in higher education have been formed. The need to improve a number of domestic platforms, in particular professional and specialized application software packages, spreadsheet editors for performing statistical procedures; digital tools for organizing group work of students and others have been justified. Proposals for further reform of the activities of the Ministry of Higher Education and Science and specific higher education institutions and directions for subsequent scientific research have been formulated.
Modern educational and methodological support for the educational process in foreign language classes in digitalization of society
Authors:   Moscow State Pedagogical University, Dmitrenko Tatiana A.
Published: March 2024

Introduction: The article analyzes the problem associated with the emergence of digital tools in the digital era, which has led to the emergence of a new didactic tool for teachers to organize the educational process, which has improved the quality of teaching a foreign language. The purpose of the article is to assess the possibilities and ways to improve the educational process in the digital era with the help of modern educational and methodological support, including digital tools. Materials and methods of research: methods of comparison and analysis of teaching practice. The research materials were the results of a survey of foreign language teachers with experience in using digital technologies. Research results: the prospect of using modern educational and methodological support for the educational process in the era of digitalization of society is substantiated; The content of the concepts “digital educational environment”, “digital tools”, “digital technologies” and “digital educational resources” is revealed. As a result of the diagnosis, an increase in the level of development of communication skills in students was revealed on the basis of modern educational and methodological support. Discussion and conclusion: analysis of the results of the study showed a positive impact on the development of foreign language communicative competence in students. It is proposed to actively use digital tools that open wide access to high-quality educational digital content and bring the language training of future specialists in the field of intercultural contacts to a new level of quality.