bluuebunny/crossref_metadata_2025 huggingface dataset:
A Hard Place
Authors: Close Ronnie
Published: January 2020

A Hard Place uses interviews and evocative visuals to explore the lingering impact of martyrdom on former hunger strikers in Northern Ireland, blurring the lines between documentary and personal memory.
Bluebell
Authors: Crofts Charlotte
Published: January 2020

This film uses the cliché of ‘stranger rape’ to set up and upset audience expectations of rape narrative, challenging the construction of women as the victims rather than survivors of rape.
Kamakha
Authors: Sharma Aparna
Published: January 2020

Aparna Sharma’s Kamakha: Through Prayerful Eyes is a lyrical documentary which explores the dilemma of representing the unrepresentable figure of the Goddess Kamakhya enshrined in an ancient fertility worship site in Northern Assam. The Temple of Kamakhya is unique in offering no image of the devi or goddess. Instead her yoni or female organs are said to be contained in a sacred rock which is also the source of a natural spring. The rock, which is covered by a red cloth, is not allowed to be photographed or filmed, but devotees are instead invited to touch it. Intrigued by this haptic form of devotion and the very invisibility of this female icon in the context of theories of woman as image / “to-be-looked-at-ness”, Aparna’s film skirts around the temple, observing worshippers’ interaction with the space and interviewing local craftsmen and artists about their interpretation of the site.
The Minkowski Property and Reflexivity of Marked Poset Polytopes
Authors: Fang Xin , Fourier Ghislain , Pegel Christoph
Published: January 2020

We study the Minkowski property and reflexivity of marked poset polytopes. Both are relevant to the study of toric varieties associated to marked poset polytopes: the Minkowski property can be used to obtain generators of coordinate rings, while reflexive polytopes correspond to Gorenstein–Fano toric varieties.
On the Sets of $n$ Points Forming $n+1$ Directions
Authors: Pilatte Cédric
Published: January 2020

Let $S$ be a set of $n\geq 7$ points in the plane, no three of which are collinear. Suppose that $S$ determines $n+1$ directions. That is to say, the segments whose endpoints are in $S$ form $n+1$ distinct slopes. We prove that $S$ is, up to an affine transformation, equal to $n$ of the vertices of a regular $(n+1)$-gon. This result was conjectured in 1986 by R. E. Jamison.
Collapsibility of Non-Cover Complexes of Graphs
Authors: Choi Ilkyoo , Kim Jinha , Park Boram
Published: January 2020

Let $G$ be a graph on the vertex set $V$. A vertex subset $W \subseteq V$ is a cover of $G$ if $V \setminus W$ is an independent set of $G$, and $W$ is a non-cover of $G$ if $W$ is not a cover of $G$. The non-cover complex of $G$ is a simplicial complex on $V$ whose faces are non-covers of $G$. Then the non-cover complex of $G$ is the combinatorial Alexander dual of the independence complex of $G$. Aharoni asked if the non-cover complex of a graph $G$ without isolated vertices is $(|V(G)|-i\gamma(G)-1)$-collapsible where $i\gamma(G)$ denotes the independence domination number of $G$. Extending a result by the second author, who verified Aharoni's question in the affirmative for chordal graphs, we prove that the answer to the question is yes for all graphs.
Kazhdan-Lusztig Polynomials of Matroids Under Deletion
Authors: Braden Tom , Vysogorets Artem
Published: January 2020

We present a formula which relates the Kazhdan–Lusztig polynomial of a matroid $M$, as defined by Elias, Proudfoot and Wakefield, to the Kazhdan–Lusztig polynomials of the matroid  obtained by deleting an element, and various contractions and localizations of $M$.   We give a number of applications of our formula to Kazhdan–Lusztig polynomials of graphic matroids, including a simple formula for the Kazhdan–Lusztig polynomial of a parallel connection graph.
Organizational Issues in Olympic Games: a Systematic Review
Authors: Ribeiro Tiago , Correia Abel , Biscaia Rui , Bason Tom
Published: January 2020

The purpose of this study is to extend previous research on organizational issues of sport megaevents through the development of a framework for the Olympic Games. A three-step approach was taken. Firstly, a systematic literature review was conducted based on journal articles, academic books, and official reports published by the International Olympic Committee (IOC) and Olympic Games Organizing Committees (OGOC). Secondly, the issues identified within the media regarding the 2016 Olympic Games were analyzed. Lastly, semistructured interviews were conducted with 10 stakeholders to further examine the organizational issues of the 2016 Rio Olympic Games. A new extended conceptual framework of organizational issues associated with the Olympic Games is then proposed. Issue categories faced by the organizing committee include politics, marketing, media and visibility, financial, planning, negotiation and ethics, operations, infrastructure, human resources, social, environmental, and legacy. These 12 dimensions of organizational issues account for a total of 76 specific issues. The article provides critical information to aid the IOC and OGOCs in understanding organizational issues that may arise in future of Olympic Games.
الاستفادة منها في تعليم اللغة العربية للومبوكيين SASAK-INDONESIA الكلمات الساساكية ذات أصل عربي في معجم
Authors: Muzamiludin  , Nuradi
Published: January 2020

Language Absorption is something that available in all Language because Languages is something lives, develops, and the absorption is not limited in only an official language of a country, but includes regional languages ​​as well as in the Sasak language. To complete this research the researcher used analytical descriptive method that appropriate with the research, because this research was aimed for collecting sasak’s, vocabulary wich from arabic in the Kamus Bahasa Sasak-Indonesia letters A to J and analyzing  meaning alteration, pronuncing, and composition, and then use it to teaching Arabic for Lombok’ people. And the result of this research indicate that there seventy one sasak language’s vocabularies that from arabic divided into Four parts according to meaning Changes and the forms  Sasak Language: 1) Vocabulary that contains the same meaning as in Arabic, example: word “AKIL” and "عاقل", 2) Vocabulary that undergoes a total changes of the meaning in Sasak language, example: word “JINAH” and "زنى", 3) Vocabulary that experiences meaning in Sasak Language, example: word “AMIL” and "عامل", 4) Vocabulary that experiences stricture meaning in Sasak language, example: word “JIMAT” and "عزيمة", study tells that the vocabulary can use to teach Arabic for lombok's people, especially for beginner.
الكلمات الملايوية ذات أصل عربي في قاموس دايا والاستيفادة منها في تعليم اللغة العبية للملايويين المبتدئين في حرف إي نموذجا
Authors: Nasution Nurmia , Herdiyanti Meitha Kartika
Published: January 2020

Arabic had entered Indonesian because of Islam which was brought by the Arab traders around the 7th century. The inclusion of Islam in the midst of the society had a considerable influence, especially among the malays people who are Muslim majority. In this study, the researcher tryed to explore 50 Malay words which are borrowed from Arabic in “Daya” dictionary, from letter A, and followed  by an analysis of the meanings and changes in the pronunciation of each word, and the method used in this study has an analitycal descriptive approach that proved that there were some many loan words in Malay that are similar to Arabic, but in some words there were changes in the way of pronunciaton, and there has expansion of the meaning, the narrowing of the meaning or complete change in the meaning. This research also proved that these loan words have a considerable role to facilitate the process of  learning Arabic for Malay students such as the introduction of Malay words derived from Arabic, and they use these words in the conversation, reading text, evaluation, and make it a tool to explain the meaning of Arabic that students have not understood.
(الوقف والابتداء في القرآن الكريم والاستفادة منهما في تعليم اللغة العربية (سورة الملك نموذجا
Authors: RUSLAN
Published: January 2020

Arabic is the noblest language absolutely, because al-quran is revealed in arabic, and with it a muslim can understand the islamic shari’a which was delivered  by the messenger of  allah, and the knowledge of Al-waqf and Al-ibtida’ is part of the branch of Arabic sciences that can help the readers of qur’an, the instructors as well as the learners in understanding the meaning of Al-quran correctly. It also helpful to avoid mistakes that can change the meaning of the verse. Therefore this research aims to explain the meaning of Al-waqf and Al-ibtida’ and to identify the kinds in surat Al-mulk and analyze them in detail and implement them in teaching arabic. In the study of this topic researcher used a descriptive analytical approach system, namely by collecting and searching for information related to the topic to achieve the results, and then analyzing these results and applying them in the field of teaching arabic. This research shows that Al-waqf and Al-ibtida’ is a science that discusses the procedure for reading the Al-qur’an to avoid a false understanding of the meaning of the verse of the Al-quran and to safeguard the authenticity of the Holy Qur’an, and Al-ibtida’ is a science that discusses the procedure for starting in reading the Al-qur’an in order to perfect its meaning, and this study shows that Al-waqf and Al-ibtida’ in surat Al-mulk are divided in to four types namely At-taam, Al-hasan, Al-kaafi and Al-qobih, and indeed Al-waqf and Al-ibtida’ play and important role in maintaining the purity of the Qur’an, and shows that the science of Al-waqf and Al-ibtida’ is closely related to the science of annahwu and interpretation, and its urgency in teaching Arabic.
PERAN GURU DALAM MEWUJUDKAN TUJUAN PEMBELAJARAN PENDIDIKAN AGAMA ISLAM DI SEKOLAH
Authors: Hidayat Tatang , Syafe’i Makhmud
Published: January 2020

The purpose of this study is to determine the role of teachers in realizing the objectives of Islamic Religious Education learning in schools.  This present study employed a qualitative approach in the form of literature study. Based on the results of the study, the learning objectives of Islamic Religious Education were easily featured by the integration between the life of the world and the hereafter. Therefore, the Islamic Religious Education learning plans should be formulated in a different method compared to other subjects.  In the learning processes of Islamic Religious Education, teachers were highly encouraged to be skillful in developing learning materials and methods. Accordingly, as the role of teachers, they were firstly encouraged to understand the pedagogical competence.  Based on the material aspects, teachers were encouraged to have ability in developing Islamic Religious Education materials not only in the realms of cognitive understanding but also in the realms of practical good deeds.  In addition, based on the methodological aspects, teachers were encouraged to courageously utilize Islamic education methods, such as the methods of Quranic education, riyadhah, rihlah, talaqi, halaqah, and many more.  With respect to the learning evaluation, teachers were encouraged to assess the aspects of the attitudes and skills of students on a daily basis in practicing Islamic teachings since it is obvious that the essence of the objectives of learning Islamic Religious  Education was to realize faithful, knowledgeable, and pious students.
أثر استراتيجية تعليم الأقران في تنمية مهارات فهم المقروء لدى الطلاب قسم الإعداد اللغوي بجامعة الراية
Authors: J.B Usman Ridwan Syahrun
Published: January 2020

The approach taken to reach the target in this study was the experimental approach because the subject needed an experiment in the field to find the results. The research sample consisted of (20) students from STIBA Ar Rayah, divided into two groups: the first was an experimental group consisting of (10) students and other officers (10) students. The results showed a positive impact from using peer tutoring education strategies in developing reading comprehension skills for students at STIBA Ar Rayah with the following results: 1) This study achieves a list of skills in reading comprehension and it is contained in five levels and the number of skills of all levels is fifteen skills. 2) This research has shown that teaching using the peer education strategy has influenced development of skills to understand reading results for students from STIBA Ar Rayah. 3) This research has also proven that the use of peer education strategies is more effective than direct teaching in developing reading comprehension skills from STIBA students Ar Rayah.
أثر استخدام خرائط المفاهيم في اكتساب المفاهيم المتعلقة بمقرر الصرف لدى طالبات المستوى السادس بجامعة الرية
Authors: Komariah Neneng , Arawati
Published: January 2020

The aim of the research was to The Effect of Using Mind Mapping on the 6th College Students in Mastery of Concept Related to Shorof Module of STIBA Ar-Raayah. In this research, the researcher chose random sampling by taking two class, the researcher took 30 college students as the sample. There were 15 in experimental class and 15 in controlled class. Experiment class was taught by mind mapping, while controlled class was taught without mind mapping (traditional method). The research conducted quantitative research by applying quasi experimental research with this method the writer can find out the effect of using mind mapping on the 6th college students in Mastery of Concept Related to Shorof Module of STIBA Ar-Raayah, the researcher practices learning by using mind mapping accompanied by examinations for each group, and then the researcher describes the results of her research. This research had shown that there are differences in exam results between the experimental class and the control class, where the results of the experimental class got (1,140) with percentages (75.93%) and the control class results got (1,080) with percentages (71.84%) and differences between both (60) with percentage (4.09%).
Effect of Threonine on the Proliferation and Viability of Porcine Granulosa Cells
Authors: Ke-Rou Zhou , Qian Zhang , Er-Hui Jin , Qian-Qian Hu , You-Fang Gu , Man Ren , Sheng-He Li
Published: January 2020

The proliferation and viability of granulosa cells directly affects the development and function of follicles. The current study examined the effect of threonine on cell morphology and cell cycle of porcine granulosa cells. It would help to understand hormone secretion, reproductive health, and disease prevention and treatment in females. Granulosa cells were isolated from pig ovaries, and different passages of cells were stained and identified by FSHR antibody. Threonine was added to the culture medium, and cells were stained with HE to examine the changes in granulosa cell morphology. Cell viability was measured using the CCK-8 assay, and cell cycle phase was determined by flow cytometry. Immunofluorescence staining showed >98% FSHR-positive cells demonstrating that the isolated granulosa cells were >95% pure. HE-staining of different passages of granulosa cells showed that cells from the second to fourth passage have stable morphology, whereas those from the fifth and subsequent passages began to degenerate and degrade. CCK-8 results showed that =0.5 mM threonine can significantly enhance granulosa cell viability after 0.5, 1 and 2 h of treatment, and cells treated with 1 mM threonine for 4 h had the highest cell viability. In contrast, 5 and 10 mM threonine significantly reduced cell viability, indicating that only a certain amount of threonine can enhance granulosa cell viability. Flow cytometry results demonstrated that the percentage of G1 phase cells was higher in the 0.1, 0.5 and 1 mM groups than in the control group, but lower in the 10 mM group than in control group. While the 5 mM group had the highest percentage of S phase cells, the 10 mM group had no S phase cells. In contrast, the percentage of G2 phase cells was much higher in the 10 mM group than in the control group and other dose groups, indicating that an appropriate amount of threonine can promote granulosa cell proliferation, but excessive threonine can inhibit cell proliferation.
Formation of strategic guidelines for activity of railway transport enterprises
Authors: Redko Viktoriia , Kerdan Olha , Kerdan Volodymyr
Published: January 2020

Purpose. The aim of the article is defining the principles of strategic management of the development of railway enterprises in the context of future changes in the railway industry.

Methodology of research. The theoretical and methodological basis for the study of strategic management in the railway industry is considered on the basis of the experience of domestic scientists. A comparative analysis of the dynamics of a number of indicators was carried out during the study, such as: the number of carried passengers, volumes of freight transported by rail, etc. The following methods are used: analytical – when considering scientific papers and strategies used in railway transport; graphical method – to reflect the developed generalized model of strategic management of JSC “Ukrzaliznytsya” activity; abstract and logical – in summarizing and formulating conclusions.

Findings. The current state of the railway transport enterprise – JSC “Ukrzaliznytsia” is analysed, which allowed to evaluate the results of its activity and to identify a number of problems of strategic nature: long-term negative dynamics of cargo transportation; depreciation of fixed assets, especially rolling stock and infrastructure; low competitiveness in the European market; imperfect information support; poor adaptability to dynamic environmental conditions and the like. A generalized model of strategic management of JSC “Ukrzaliznytsya” activity was developed based on systematization of data presented in the Strategy of JSC “Ukrzaliznytsia” for 2019-2023.

Originality. Problems and key factors that will influence the effective implementation of the JSC Strategy “Ukrzaliznytsia” for 2019-2023 are identified.

Practical value. The conducted analysis of the results of the activity of JSC “Ukrzaliznytsia” in 2017–2018 allowed us to highlight the significant achievements and problems of the enterprise in need of solution. It is determined that the strategic guidelines for the activity of the railway transport company should be formed in the context of achieving its mission, taking into account the interests of the stakeholders and respecting corporate values.

Key words: strategic development landmarks; rail transport; Ukrzaliznytsia; limited development strategy.
Evaluation of Antioxidant Capacities and Phenols Composition of Wild and Cultivated Berries
Authors: Stanciu Gabriela , Lupsor Simona , Tomescu Aneta , Sirbu Rodica
Published: January 2020

The study presents original results concerning analytical characterization of alcoholic extracts of four wild berries (blueberries, blackberries, red currants and raspberries) and two cultivated berries (black cherries and strawberries). Total and some individual phenols concentrations were determined using molecular absorption spectrometry (modified Folin Ciocalteu method) and HPLC-DAD technique. The measurement of lipid-soluble antioxidant capacity (ACL) was done by photochemiluminescence method using trolox as standard.The highest total phenolic content was registered in blueberries (543.5 mg/100g f.w.), while the lowest was found in raspberries (344.5 mg/100g f.w.).HPLC � DAD analysis indicated the presence of six individual polyphenolic compounds in different concentrations: gallic acid (62.664 - 178.821 mg/100 g f.w); chlorogenic acid (30.152 - 243.923 mg/100g f.w.); 3-O-methyl-gallic acid (2.035 - 4.907 mg/100 g f.w.); caffeic acid (0.401 - 5.664 mg/100 g f.w.); p-coumaric acid (4.252 - 10.806 mg/100 g f.w.) and cinnamic acid (0.665-0.958 mg/100 g f.w.). ACL results showed values between 54.00 and 1152 �mols trolox/100 g f.w.
Nanocomposite for Rapid Prototyped Complete Denture Eighteen months follow-up on clinical performance
Authors: Cristache Corina Marilena , Totu Eugenia Eftimie , Grosu Alexandra Raluca , Ene Oana , Beuran Irina Adriana , Burlibasa Mihai
Published: January 2020

The aim of the present study was to evidence the improved behavior of our modified PMMA-TiO2 nanocomposite material used to obtain 3D printed complete dentures. A protocol for long-term rapid prototyping complete denture manufacturing using our nanocomposite material, completely characterized and the evaluation of the clinical performance and complications after eighteen months of continuous wearing was also described. Thirty-five fully edentulous patients were enrolled in this prospective clinical study and forty-five complete dentures (31 maxillary and 14 mandibular) have been obtained using an additive manufacturing technology. Due to the good performances of the nanocomposite material, no major functional complications for the obtained medical devices occurred and the clinical outcomes for the 3D printed dentures were favorable evaluated at eighteen months follow up.
Effect of Chemical Composition on Hard Deposits Properties in the Case of Weld Refurbishment of Heavy Crushing Hammers
Authors: Garleanu Delia , Garleanu Gabriel
Published: January 2020

The article presents a study on the influence of chemical composition on the hardness and microstructural properties in case of crushing hammers used in stone quarries that can be refurbishment by welding, using different types of filler material. In this research paper it is analyzed the effect that chemical composition of the filler material exerts on the microstructure of the loading area, the dilution effects at the welding interfaces level and the modification of the microhardness. Three types of filler material with different chemical composition have been used in order to choose the optimal version that ensures the best performance in operation.
RAS Inhibition in Haemodyalisis Patients. Impact on mortality
Authors: Apostol Adrian , Chisavu Lazar , Albulescu Nicolae , Stoian Dana , Schiller Adalbert
Published: January 2020

Patients with chronic kidney disease (CKD) represent a special category of risk. As part of the renal and cardiovascular continuum from risk factors to end stage diseases, they develop clinical syndromes with potentially severe prognosis. Patients on dialysis have severe cardiac risk, have a peculiar hyperlipemic profile with intense atherogenic effect, phosphocalcic metabolic alterations and thus a higher rate of development of atheroma and degenerative valve diseases. They have higher cardiovascular mortality and morbidity being potential candidates for aggressive reduction of risk factors. Dialysate patients are exposed to higher risk of ischemic and arrhythmic events. Echocardiographic assessment of these patients is extremely important in risk stratification and treatment strategy in order to improve prognosis. Drugs proved to improve cardiac remodeling, reduce hypertrophy and LV mass and enhance ejection fraction, improved prognosis.
Visible Spectrophotometric Analysis Method of Sodium Metamizole in Tablets
Authors: Gavat Cristian Catalin , Vasilescu Leonard Vasile , Marculescu Afrodita Doina
Published: January 2020

The aim of this research was to exactly quantify pure sodium metamizole from tablets , using a spectrophotometric analysis in Visible range. The method applied has been subjected to a validation protocal which consisted in analyzing the following parameters: linearity of the method, detection limit (LD) , quantitation limit (LQ), Sandell�s sensitivity, interference of excipients, stability of prepared solutions, method and system precision, accuracy of the method. Following actual dosing, pure sodium metamizole amount in tablet of pharmaceutical was found to be 477.477 mg assigned to a percentage content of 95.495 %, very close to official declared amount (500 mg), with an maximum average percentage deviation of only 4.505 % from the official declared active substance content. This value was situated below the maximum admissible percentage deviation from stated active substance content (� 5%), established by Romanian Pharmacopoeia, X-th Edition rules.
Effect of Freeze-drying and Oven-drying Methods on Flavonoids Content in two Romanian Grape Varieties
Authors: Oprica Lacramioara , Antohe Radu Gheorghe , Verdes Andreea , Grigore Marius Nicusor
Published: January 2020

The aims of this work was to investigate the effect of thermal drying method (vacuum oven drying), and nonthermal drying method (freeze drying) on the flavonoids content in two red grape varieties (Cabernet Sauvignon and Merlot) from different grape components (seed, skin, and pulp) collected from two experimental fields, Bucium and Copou (North East of Romania). In general, the fresh skin of Cabernet and Merlot varieties has the highest flavonoids content followed by those obtained by oven-drying and freeze-drying process. A similar situation was observed in the other component of grape varieties like pulp and seeds meaning in the way that the flavonoid content in oven-dried samples were higher than that in the freeze-dried samples. In addition, from both varieties, Merlot collected from Bucium presented the highest content compared with Cabernet.
Physico - Chemical and Morphologic Structural Characterization of the Red Mud Obtained in the Romanian Alumina Plant
Authors: Georgescu Vasile , Bombos Mihaela , Calin Catalina , Bombos Dorin
Published: January 2020

The red mud is the main insoluble waste product from the manufacture of alumina by the Bayer hydrometallurgical process. Due to the accumulation in large quantities (0.8-1.2 metric tons waste / 1 metric ton of alumina) with a relatively high content of residual alkali and small granulation, it has been subject to many research activities, especially related to the techniques of neutralizing and enhancing its reuse under the form of various subproducts. This paper presents the results of the work undertaken by the collective of authors to evaluate the physico-chemical and morphological structure of red mud resulting from alumina production. The physico-chemical and morphological structure were analyzed using complex analytical methods (ICP-AES/OES, DCP, AAS, EDS-EDAX, SEM, DTAC, XRF, XRD, optical microscopy). The aim was to identify potentially active compounds for various environmental applications. To estimate the average chemical composition, by element, we used dispersion analysis, through the Gauss normal distribution method.
Azadirachta indica Leaf as a Corrosion Inhibitor for Coper in Nitric Acid
Authors: Mitu Liviu , Rubavathi Sweetlin Rajula , Subramani Muthupoongodi , Linda T. , Balakumar S.
Published: January 2020

The effect of Azadirachta indica leaf (AIL) extract on the corrosion of copper in 1M HNO3 was investigated by weight loss technique. The result showed that the corrosion rate decreased in the presence of plant extract and inhibition efficiency increased with increasing the concentration of extract. The decreased corrosion rate was due to adsorption of plant extract which was discussed on the basis of Langmuir adsorption isotherm.
Effects of Berberis vulgaris Extract on Lipid Profile, Kidney and Liver Function in Experimental Dyslipidemia
Authors: Neag Maria Adriana , Bocsan Ioana Corina , Catinean Adrian , Vesa Stefan Cristian , Balan Gheorghe G. , Parvu Marcel , Muntean Dana Maria , Vlase Laurian , Melincovici Carmen Stanca , Pop Raluca , Buzoianu Anca Dana
Published: January 2020

The ability of Berberis vulgaris bark extract (BVE) to improve the lipid profile was evaluated in an experimental model of dyslipidemia, along with its effects on liver and kidney functions. Fifty rats divided into five groups of ten animals each were fed with normal or lard-based diet and orally treated with 0.9% saline solution, atorvastatin (2.5 mg/kg per body weight) or extract of BVE (300 and 500 mg/kg/day) for eight weeks. Lipid profile, liver and renal functions were assessed in normal and diet-induced hypercholesterolemic rats. The results were compared between the groups treated with Berberis extract and the group without treatment, respectively that one treated with the standard drug (atorvastatin). Administration of BVE or atorvastatin significantly decreases the elevated serum lipid profile (p [0.05). The extract also protects against dyslipidemia-induced non-alcoholic fatty liver disease (NAFLD). The activities of the plant extract are dose dependent and it compares favorably with the standard drug atorvastatin. Variations in aspartate aminotransferase (AST), alanine aminotransferase (ALT), and urea level measurements were neither different between the two determinations nor between groups, but creatinine values decreased in rats in the BVE or atorvastatin-treated groups. The findings of the current study have suggested that BVE intake suppresses the accumulation of hepatic lipids and lipid parameters and reduce the risk of NAFLD. So, BVE can be useful in hypercholesterolemia.
Biochemical Markers of Bone Turnover in Rheumatoid Arthritis Patients Treated with Glucocorticoids
Authors: Macovei Luana Andreea , Burlui Alexandra , Rezus Elena
Published: January 2020

Osteocalcin and deoxypyridinoline levels were measured in 55 RA patients during and after glucocorticoid therapy with prednisone, methylprednisolone and cortisone. A decrease of 27% of the bone resorption marker deoxypyridinoline (from 10.13 to 7.4) and an increase of 23% of the bone formation marker osteocalcin (from 16.3 to 20.1) were also clinically confirmed by the presence of osteoporosis in 74% of patients receiving corticosteroid treatment as compared with only 31% in the control group.
Tranexamic Acid - Major Antifibrinolytic Agent Used to Achieve Hemostasis in Hemophilic Patients with Anti-Factor VIII Anti-Bodies Who Must Undergo Total Joint Replecement
Authors: Badulescu Oana Viola , Ciocoiu Manuela , Filip Nina , Veringa Vlad
Published: January 2020

Hemophilia is a congenital coagulopathy characterized by a deficiency of coagulation factor VIII or IX. The main complication of this hemopathy is represented by the hemorrhagiparous phenomena that affect mainly the musculoskeletal system. Of the various chronic complications of this condition, hemarthrosis is responsible for the onset of chronic arthropathy, which is a disabling condition. In addition to hematologist-prescribed coagulation factor replacement therapy, acute hemarthrosis and chronic arthropathy management requires close collaboration with both orthopedic surgeons and physiotherapists. This multidisciplinary collaboration is essential both to prevent the onset of hemarthroses and to manage acute bleeding episodes, to assess joint function and to effectively treat hemophilic chronic arthropathy. Hemophilic arthropathy causes significant joint instability and reduced mobility or even total ankylosis, which may lead to permanent disability and hence to a decrease in the patient�s quality of life. From an orthopedic point of view, disabling hemophilic arthropathy may be treated by surgery. Achieving effective hemostasis is vital in order to be able to perform these extremely difficult surgical procedures, due to the high risk of bleeding. This paper aims at highlighting the hemostatic efficacy of tranexamic acid in orthopedic surgery in hemophilic patients who must undergo total joint replacement.
A Non-invasive, Easy to Use Medical Device for Arterial Stiffness
Authors: Juganaru Iulius , Luca Constantin Tudor , Dobrescu Andreea-Iulia , Voinescu Oana , Puiu Maria , Farcas Simona , Andreescu Nicoleta , Iurciuc Mircea
Published: January 2020

Arterial stiffness is classified as a useful marker of early vascular damaging and a predictor of cardiovascular events in young people. We aimed to present the efficacy of a non invasive device in cardiovascular diseases prevention. Using the Arteriograph device, it was performed a cross sectional, non-invasive study in 313 healthy students. Non-invasive screening of apparently healthy young subjects with high WTH ratio values may be beneficial for detecting early, asymptomatic arterial atherosclerosis.
Raspunsul gazdei la hepatita cronica virala B
Authors: Cringus Laura-Ioana , Petrescu Florin , Calborean Veronica , Rotaru Luciana Teodora , Marginean Cristina , Mesina Cristian , Bunescu Marius Gabriel , Dinescu Venera Cristina , Gheorman Victor , Dijmarescu Anda Lorena , Udristoiu Ion , Ciobanu Daniela
Published: January 2020

This review discusses and tries to demonstrate the importance of proinflammatory and antiinflammatory cytokines in HBV infection. Hepatitis B virus is a virus that is both hepatotropic and non-cytopathic. It causes the development of liver diseases which could progress into both acute and chronic versions. The virus is very widespread and results in the death of quite a number of people each year. The outcome of the viral infection is a result of immunologically mediated event. This means that the outcome is determined by the response of the immune system of the host. The infection can lead to several different liver diseases as well as fibrosis and cirrhosis. When an infection occurs, there is an attempt by the body to fight it via the use of several mechanisms. One of these is the use of cytokines (which are proteins). There exist different kinds of cytokines of which interleukin-10 and interferon gamma are very important. Interleukin-10 is an anti-inflammatory cytokine which inhibits the effector mechanism of Th1 cytokines. It performs hepatoprotective and anti-inflammatory functions and also upregulates Th2 cytokines. The function and relevance of this cytokine in the pathogenesis of liver diseases cannot be underemphasized. Interferon gamma, on the other hand, is a pro-inflammatory cytokine which seeks to eliminate and expunge the virus from the liver upon infection. It does this by congregating at the site of infection which subsequently results in inflammation and eventually liver fibrosis. This effect could be reversed by administering another type of interferon; interferon alpha.
Evaluation of Echocardigraphic Parameters in Patients with Rhythm Disorders Associated with Chronic Hepatic Diseases
Authors: Calborean Veronica , Udristoiu Ion , Docea Andreea Denisa , Hodorog Mihai Cristian , Dinescu Sorin Nicolae , Criciotoiu Oana , Stanca Diana , Mita Adrian , Davitoiu Dragos Virgil , Baleanu Vlad Dumitru , Romanescu Florin Marius , Bica Marius , Mirea Cecil Sorin , Dinescu Venera Cristina
Published: January 2020

Due to the increased frequency of cardiovascular diseases in the evolution of chronic liver disease, we proposed to assess echocardiographic changes in patients with rhythm disorders associated with chronic liver disease. To analyze the degree of cardiac damage, each patient was subjected to a complete cardiovascular examination.
Actual Study Regarding Quantitative Determination of Tetracyclines by Electrical Analysis Techniques and Methods Potentiometric sensors for tetracycline
Authors: Mavritsakis Nikolaos , Ursu Vasile Emil , Ionescu Elena , Ganescu Anca
Published: January 2020

Ion-selective electrodes have gained a wide applicability in pharmaceutical analysis and the literature has some data and their use for the determination of tetracyclines. Ion-selective electrodes for tetracycline were built using different electroactive materials and studied their performance. A working group from the Department of Analytical Chemistry of the University of Bucharest, in collaboration with a group of teaching staff from the Department of Chemistry at the Faculty of Sciences, University of Craiova, has developed and tested a series of ion-selective electrodes for tetracycline, [1], minocycline [2] and doxycycline [3]. These electrodes were tested for the determination of these tetracyclines from commercial tablets.
Evaluation of the Degree of Dental Anxiety in a Lot of Patients Altered in Young Adults
Authors: Raftu Gheorghe , Sin Elena-Claudia , Caraiane Aureliana , Bustiuc Steliana Gabriela , Briceag Raluca
Published: January 2020

The study aims at identifying and highlighting dental anxiety in a group of young adults, analyzing patients� concerns about the main dental treatment procedures, and establishing statistical relationships between anxiety and gender, the background, level of education, socio-economic status and knowledge of habits of care and hygiene of oral cavity characteristic of the studied group. The study group consists of 150 female (50%) and male (50%) patients , aged between 20 and 40 years. The inclusion criteria in the batch were those related to the age range of 20 to 40 years.Two respondents (Corah�s Dental Anxiety Scale, Revised (DAS-R)) were given two questionnaires ( Corah�s Dental Anxiety Scale, DAS-R), and the second questionnaire contained 7 questions about the habits dental care). Most patients� concerns about the main procedures of dental treatment / other concerns are: dental extraction, material expenses, possibility of treatments and shame she felt oppressed health of the oral cavity. Regardless of the level of dental anxiety, the oral cavity hygiene habits are not properly performed by patients, with an increased tendency for them to be disregarded by patients with severe dental anxiety.
Cavitation Erosion Resistance of Laser Beam Nitride Layers of X5CrNi18-10 Stainless Steel
Authors: Bordeasu Ilare , Salcianu Cornelia Laura , Popoviciu Mircea Octavian , Mitelea Ion
Published: January 2020

The use of nitration in technical applications, as thermochemical treatment, regardless of the used method (ionic, gas or laser beam nitration) is realized to obtain a nitrogen rich layer, which increase the resistance to shock or abrasion, as a result of the high hardness obtained. All the previous cavitation researches showed that hardness is an important mechanical properties, for cavitation erosion resistance increase. The present paper show some results regarding the cavitation erosion behavior of laser beam nitrated layers. As basic material was used the austenitic stainless steel X5CrNi18-10. This material is frequently used for manufacturing details subjected to cavitation, such as valves, drawers of hydraulic distribution and regulation devices, or the retaining ring for butterfly valves. There were used three power regimes of the laser beams: 120 W, 180 W and 240 W. To obtain cavitation erosion was used the standard device with piezo-ceramic crystals of Timisoara Polytechnic University Cavitation Laboratory. The cavitation erosion comparisons, both with the basic material subjected only to the common thermochemical treatments and with the laboratory cavitation standard steel (OH12NDL), show that the nitrated surfaces presents increased cavitation erosion behavior, the principal factor being the important hardness increase of the nitrated layer. We mention also, that for higher laser beam powers the thickness of the nitrated layer increases. All the images obtained at the end of tests show that the cavitation exposure was stopped before overtaking the nitrated layer. So, all our results concern only the hardened layers.
Tarnita Polluted Area: Accumulation of Heavy Metals and Nutrients from the Soil by Woody Species
Authors: Iacoban Carmen , Risca Ioan Marian , Roibu Catalin , Todirascu Ciornea Elena , Necula Radu , Ilieva Darya , Sandu Ion , Drochioiu Gabi
Published: January 2020

Heavy metals are destructive environmental stressors that greatly reduce plant growth and productivity. Here, the content of some heavy metals (Fe, Cu, Zn and Mn) and mineral nutrients (Ca, Mg and K) in silver fir (Abies alba Mill.) and European beech (Fagus sylvatica L.) wood from two sites in the Tarni�a mining area (North-Est Romania) was analyzed. The first site (no. 1) is located near a big tailings dump, whereas the other one (no. 2) is situated 6 km South, in a less polluted area. The purpose of this work was to evaluate the present-date levels of such elements in the investigated biological materials and to compare them. Measurements of heavy metal content in wood were performed with an AAS flame spectrometer, whereas an ICP-OES spectrometer was used for soil and tailings dump samples. The Mn content was higher in the site no. 1 located near the dump, for both species, but the difference was statistically significant only for the European beech trees. The Zn content of samples from the site no. 1 was lower than that corresponding to the second one (no. 2) for both species, but significant for the silver fir only. However, there was not found a significant difference in respect to both iron and copper in the samples collected from the two species and two different sites. Furthermore, the content of Ca and Mg of both species was found higher for the site no. 2, suggesting a better state of nutrition of the investigated trees than of those located near the tailings dump. The content of calcium and magnesium of silver fir was negatively correlated with the diameter of the trees collected from both sites.
Determining the Influence of Alcohol on the Pharmacological Effect of Benzodiazepines by Molecular Docking Tehnique
Authors: Rotaru Luciana Teodora , Nedelea Paul , Varut Renata-Maria , Petrica Alina , Nica Silvia , Bouros Catalin , Cimpoesu Diana , Corlade Mihaela , Banicioiu Covei Mihai , Novac Marius
Published: January 2020

Benzodiazepines represents a large category of medications that were originally developed to treat anxiety disorders or issues with anxiety, seizures, and issues with sleeping. The most common drugs abused along with benzodiazepines are other benzodiazepines, prescription pain medications and alcohol. Alcohol and benzodiazepine have a synergistic depressant effect on the central nervous system. Combining alcohol with benzodiazepines can be dangerous practice even if it is engaged in only occasionally. In the present study, using molecular docking technique we followed the binding energy of benzodiazepines with benzodiazepine receptor and efficacy of the flumazenil antidote against benzodiazepine in the presence and absence of alcohol. We realized correlation study of molecular descriptors value of benzodiazepines with benzodiazepine-GABAA complex binding energy.
Optimization and Kinetics of the Solid-liquid Extraction Process of Polyphenols from Black Mulberry Fruit
Authors: Kostic Emilija , Nikolic Goran M. , Mitic Snezana , Dimitrijevic Danica , Mitic Milan
Published: January 2020

This paper investigates the influence of operating conditions and extraction techniques (maceration and ultrasonic) on the yield and extraction of dry extract, total phenolic, flavonoids and anthocyanins from black mulberry fruit (Morus nigra L.). The optimal extraction conditions and kinetic parameters of the extraction process are determined.
Hydrodynamic Surface Evaluation of a Polymeric Reverse Osmosis Membrane Using a Crossflow Cell
Authors: Dascalu Mihaela-Elena , Nedeff Florin , Mosnegutu Emilian , Sandu Ioan Gabriel , Lopez-Ramirez Juan Antonio
Published: January 2020

The purpose of this research was to visualize the fouling process of a flat-sheet polymeric membrane into a flow cell, using particles to study their deposition onto the membrane surface. This set of experiments was analyzed from an imagistic point of view, designing for this purpose a measuring installation where hydrodynamic surface evaluation was carried out with an image processing concerning to the reverse osmosis operation. To ensure the measurements accuracy, calculations, logical approximation, and comparisons were made with existing and verified models, revealing that the differences were insignificant.
Electroplating of Co-W and Co-Mo Alloys from Na2WO4 Ionic Melts
Authors: Malyshev Victor , Gab Angelina , Survila Arvydas , Donath Cristina , Neacsu Elena Ionela , Popescu Ana Maria , Constantin Virgil
Published: January 2020

The cathodic reduction processes of cobalt (II), tungsten (VI) and molybdenum (VI) in Na2WO4 melts are discussed. Electrochemical behavior of cobalt in a tungstate melt, as well as the effect of electrolysis conditions on the composition and structure of Co-W and Co-Mo alloys deposits from tungstate-molybdate melts is also studied. With a decrease in the concentration of cobalt ions and an increase in the concentration of molybdenum (tungsten) ions in the melt, the phase composition of cathodic deposits is shown to change from individual cobalt to individual molybdenum (tungsten) via a series of cobalt-molybdenum (tungsten) compounds of various compositions.
Numerical Simulation of the Hydrodynamics of Some Sectors of the Prute River
Authors: Marusic Galina , Panaitescu Valeriu
Published: January 2020

This paper addresses issues related to the determination of hydrodynamics of aquatic systems, with the application of computational fluid dynamics (CFD) analysis. The importance of knowing the hydrodynamics of aquatic systems for solving water pollution problems, as well as their prevention, is discussed. A case study regarding the determination of the water flow characteristics using CFD for some sectors of the Prut river is presented.
Clinical and Biological Study on the Relevance of Hiperfibrinogenemyme in Cardiovascular Pathology of the Obez Patient
Authors: Mavritsakis Nikolaos , Ursu Vasile Emil , Ganescu Anca , Ionescu Elena
Published: January 2020

Obesity is a major public health problem, being the second leading cause of death that can be prevented after smoking. Currently, more than 1 billion people have body mass overweight (overweight) and over 300 million suffer from obesity. In the next two decades, the number may double, which will lead to a significant increase in associated pathology, and the average life span of obese patients is 8-10 years shorter than normal subjects [1, 2]. The prevalence of obesity and overweight increases practically in all countries and age groups in the world, and the economic cost of obesity is estimated to be 2-7% of all health expenditure [4]. Adipose tissue, and in particular visceral intraabdominal adipose tissue, is a metabolic active endocrine organ capable of synthesizing and releasing into the blood a wide variety of peptidic and non-peptidic compounds that may play a role in cardiovascular homeostasis.
Assessment of Serum Cystatin C as an Early Biomarker of Carotid Atherosclerosis
Authors: Grigoras Mirela , Lighezan Daniel , Folescu Roxana , Faur Cosmin Ioan , Dejica Simina , Nicola Patricia , Dahma George , Baaj Teim , Tilea Ioan , Varga Andreea , Ardeleanu Elena , Pascu Alina Mihaela , Poroch Vladimir , Gurgus Daniela
Published: January 2020

The aim of this study was to establish the correlation between the value of serum cystatin C (Cys C) and carotid atherosclerosis in patients without chronic kidney disease and to determine the serum Cys C cut-off level for carotid atherosclerosis diagnosis. The study was performed between October 2014 and June 2018, and included 256 patients from 20 family medicine offices of Timis County, both from urban and rural areas. The patients completed a socio-demographic questionnaire, and were clinically examined by their general practitioner and investigated by laboratory tests and carotid ultrasound. The mean age of the patients with high serum Cys C (study group 1) was 74 years (82% male), while in study group 2 (with low serum Cys C values) the mean age was 56 years old (63% male). Cys C levels were significantly correlated with serum creatinine and estimated glomerular filtration rate. In the group with elevated levels of Cys C we found an increased incidence of obesity, hypertension, diabetes and carotid atherosclerosis. Multivariate analysis showed that the increased levels of Cys C were associated with a maximum carotid plaque thickness (MCPT) �2 mm (OR: 2.86, 95% C.I.: 1.13-7.97). The serum Cys C cut-off level for the diagnosis of atherosclerosis determined by ROC (receiver operating characteristic) curve was 0.73 mg/dL.