bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Data from Targeting Epigenetics for Cancer Prevention By Dietary Cancer Preventive Compounds—The Case of miRNA
Authors: Kong Ah-Ng Tony , Zhang Chengyue , Su Zheng-Yuan
Published: April 2023

Supplementary Data from Targeting Epigenetics for Cancer Prevention By Dietary Cancer Preventive Compounds—The Case of miRNA
Related Article from Cotargeting Cyclin D1 Starts a New Chapter in Lung Cancer Prevention and Therapy
Authors: Kim Edward S. , Lee J. Jack , Wistuba Ignacio I.
Published: April 2023

Related Article from Cotargeting Cyclin D1 Starts a New Chapter in Lung Cancer Prevention and Therapy
Supplemental Figures 1-3 from UCP2 Knockout Suppresses Mouse Skin Carcinogenesis
Authors: Li Wenjuan , Zhang Chunjing , Jackson Kasey , Shen Xingui , Jin Rong , Li Guohong , Kevil Christopher G. , Gu Xin , Shi Runhua , Zhao Yunfeng
Published: April 2023

Supplemental Figures 1-3. Supplementary Figure 1. Ki-67 (to detect cell proliferation) and TUNEL (to detect apoptosis) staining of skin epidermal tissues at the end of the skin carcinogenesis study (amplification: 20x). Supplementary Figure 2. Detection of the protein levels of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 (PFKFB2) in mouse skin epidermal tissues at the end of the carcinogenesis study. Supplementary Figure 3. Histological examination of invaded tumor (arrow) and surrounding neutrophils (arrow head). A tumor section from a DMBA/TPA treated wild-type mouse was chosen (amplification: 40x).
Perspective on this Article from Green Tea Polyphenols Prevent UV-Induced Immunosuppression by Rapid Repair of DNA Damage and Enhancement of Nucleotide Excision Repair Genes
Authors: Katiyar Santosh K. , Vaid Mudit , van Steeg Harry , Meeran Syed M.
Published: April 2023

Perspective on this Article from Green Tea Polyphenols Prevent UV-Induced Immunosuppression by Rapid Repair of DNA Damage and Enhancement of Nucleotide Excision Repair Genes
Supplementary Table 2 from The Parity-Associated Microenvironmental Niche in the Omental Fat Band Is Refractory to Ovarian Cancer Metastasis
Authors: Cohen Courtney A. , Shea Amanda A. , Heffron C. Lynn , Schmelz Eva M. , Roberts Paul C.
Published: April 2023

PDF file - 76K, Supplementary Table S2. Cancer-associated immune cell changes in the peritoneal serous fluid (PSF). PSFs from young adult nulliparous mice (yNP) and mature adult parous mice (aP) that were either implanted with MOSE-LFFLv cells or administered PBS (na�ve) were harvested at 3 weeks post-implantation by peritoneal lavage. Immune cell subsets were identified by cell surface marker expression using FACS analysis and are presented as a percentage of total CD45+ cells
Supplementary Table 1 from Evaluation of Clinical Criteria for the Identification of Lynch Syndrome among Unselected Patients with Endometrial Cancer
Authors: Bruegl Amanda S. , Djordjevic Bojana , Batte Brittany , Daniels Molly , Fellman Bryan , Urbauer Diana , Luthra Rajyalakshmi , Sun Charlotte , Lu Karen H. , Broaddus Russell R.
Published: April 2023

PDF file - 83KB, Table summarizing previously published SGO criteria for Lynch Syndrome-associated endometrial cancer.
Supplementary Figure 3 from Eflornithine (DFMO) Prevents Progression of Pancreatic Cancer by Modulating Ornithine Decarboxylase Signaling
Authors: Mohammed Altaf , Janakiram Naveena B. , Madka Venkateshwar , Ritchie Rebekah L. , Brewer Misty , Biddick Laura , Patlolla Jagan Mohan R. , Sadeghi Michael , Lightfoot Stan , Steele Vernon E. , Rao Chinthalapally V.
Published: April 2023

Supplementary Figure 3. Schematic representation of effect of DFMO on ODC pathway
Supplementary Figure 1 from Eflornithine (DFMO) Prevents Progression of Pancreatic Cancer by Modulating Ornithine Decarboxylase Signaling
Authors: Mohammed Altaf , Janakiram Naveena B. , Madka Venkateshwar , Ritchie Rebekah L. , Brewer Misty , Biddick Laura , Patlolla Jagan Mohan R. , Sadeghi Michael , Lightfoot Stan , Steele Vernon E. , Rao Chinthalapally V.
Published: April 2023

Supplementary Figure 1. Immunohistochemistry of Ki67, cyclinD1, Rb and p16
Supplementary Figure 1 from Topical Treatment with Black Raspberry Extract Reduces Cutaneous UVB-Induced Carcinogenesis and Inflammation
Authors: Duncan F J. , Martin Jason R. , Wulff Brian C. , Stoner Gary D. , Tober Kathleen L. , Oberyszyn Tatiana M. , Kusewitt Donna F. , Van Buskirk Anne M.
Published: April 2023

Supplementary Figure 1 from Topical Treatment with Black Raspberry Extract Reduces Cutaneous UVB-Induced Carcinogenesis and Inflammation
Table S1 from Gonadal Tumor in Frasier Syndrome: A Review and Classification
Authors: Ezaki Jiro , Hashimoto Kazunori , Asano Tatsuo , Kanda Shoichiro , Akioka Yuko , Hattori Motoshi , Yamamoto Tomoko , Shibata Noriyuki
Published: April 2023

Table S1. Data and reference of all 88 cases we have analyzed.
Related Articles from Examining Stools for Colon Cancer Prevention: What Are We Really Looking for?
Authors: Byers Tim
Published: April 2023

Related Articles from Examining Stools for Colon Cancer Prevention: What Are We Really Looking for?
Supplementary Table 1 from Frequency of Rearrangements in Lynch Syndrome Cases Associated with MSH2: Characterization of a New Deletion Involving both EPCAM and the 5′ Part of MSH2
Authors: Pérez-Cabornero Lucia , Sanz Mar Infante , Sampedro Eladio Velasco , Aras Enrique Lastra , Becares Alberto Acedo , Pino Cristina Miner , Domínguez Mercedes Durán
Published: April 2023

PDF file - 98K, Experimental conditions of EPCAM-MSH2 deletion by a routine PCR.
Related Article from Molecular Imaging of Inflammation and Carcinogenesis
Authors: Ostrov David A. , Contag Christopher H.
Published: April 2023

Related Article from Molecular Imaging of Inflammation and Carcinogenesis
Supplementary Figure 6 from Targeted DNA Methylation Screen in the Mouse Mammary Genome Reveals a Parity-Induced Hypermethylation of Igf1r That Persists Long after Parturition
Authors: Katz Tiffany A. , Liao Serena G. , Palmieri Vincent J. , Dearth Robert K. , Pathiraja Thushangi N. , Huo Zhiguang , Shaw Patricia , Small Sarah , Davidson Nancy E. , Peters David G. , Tseng George C. , Oesterreich Steffi , Lee Adrian V.
Published: April 2023

Supplemental Figure S6. Supervised hierarchical clustering and cell type content analysis. (A) Heatmaps displaying supervised hierarchical clustering of hypermethylated and hypomethylated windows including dendrograms (Red=Methylated, Green=Unmethylated).
Supplementary Table 1 from Curcumin Modulates MicroRNA-203–Mediated Regulation of the Src-Akt Axis in Bladder Cancer
Authors: Saini Sharanjot , Arora Sumit , Majid Shahana , Shahryari Varahram , Chen Yi , Deng Guoren , Yamamura Soichiro , Ueno Koji , Dahiya Rajvir
Published: April 2023

PDF file - 51K
Supplementary Figure 4 from Curcumin Modulates MicroRNA-203–Mediated Regulation of the Src-Akt Axis in Bladder Cancer
Authors: Saini Sharanjot , Arora Sumit , Majid Shahana , Shahryari Varahram , Chen Yi , Deng Guoren , Yamamura Soichiro , Ueno Koji , Dahiya Rajvir
Published: April 2023

PDF file - 503K, Restoration of miR-203 expression suppresses tumorigenicity in vitro in J82 cell line.
Supplementary Figure 2 from Curcumin Modulates MicroRNA-203–Mediated Regulation of the Src-Akt Axis in Bladder Cancer
Authors: Saini Sharanjot , Arora Sumit , Majid Shahana , Shahryari Varahram , Chen Yi , Deng Guoren , Yamamura Soichiro , Ueno Koji , Dahiya Rajvir
Published: April 2023

PDF file - 130K, Curcumin augments miR-203 expression in bladder cancer cell lines J82 and TCCSUP.
Supplementary Table 2 from Noninvasive Detection of Candidate Molecular Biomarkers in Subjects with a History of Insulin Resistance and Colorectal Adenomas
Authors: Zhao Chen , Ivanov Ivan , Dougherty Edward R. , Hartman Terryl J. , Lanza Elaine , Bobe Gerd , Colburn Nancy H. , Lupton Joanne R. , Davidson Laurie A. , Chapkin Robert S.
Published: April 2023

Supplementary Table 2 from Noninvasive Detection of Candidate Molecular Biomarkers in Subjects with a History of Insulin Resistance and Colorectal Adenomas
Supplementary Table S3 from Hepatitis B Virus Combo Mutations Improve the Prediction and Active Prophylaxis of Hepatocellular Carcinoma: A Clinic-Based Cohort Study
Authors: Yin Jianhua , Wang Junxue , Pu Rui , Xin Haiguang , Li Zixiong , Han Xue , Ding Yibo , Du Yan , Liu Wenbin , Deng Yang , Ji Xiaowei , Wu Ming , Yu Min , Zhang Hongwei , Wang Hongyang , Thompson Timothy C. , Ni Wu , Cao Guangwen
Published: April 2023

Supplementary Table S3. Cox regression analysis of factors significantly affected liver death in antiviral-treated cohort patients with chronic HBV infection.
Supplementary Table S2 from Hepatitis B Virus Combo Mutations Improve the Prediction and Active Prophylaxis of Hepatocellular Carcinoma: A Clinic-Based Cohort Study
Authors: Yin Jianhua , Wang Junxue , Pu Rui , Xin Haiguang , Li Zixiong , Han Xue , Ding Yibo , Du Yan , Liu Wenbin , Deng Yang , Ji Xiaowei , Wu Ming , Yu Min , Zhang Hongwei , Wang Hongyang , Thompson Timothy C. , Ni Wu , Cao Guangwen
Published: April 2023

Supplementary Table S2. Cox analysis of factors significantly affected hepatocellular carcinoma occurrence in antiviral-treated cohort.
Supplementary Figure 2 from Hepatitis B Virus Combo Mutations Improve the Prediction and Active Prophylaxis of Hepatocellular Carcinoma: A Clinic-Based Cohort Study
Authors: Yin Jianhua , Wang Junxue , Pu Rui , Xin Haiguang , Li Zixiong , Han Xue , Ding Yibo , Du Yan , Liu Wenbin , Deng Yang , Ji Xiaowei , Wu Ming , Yu Min , Zhang Hongwei , Wang Hongyang , Thompson Timothy C. , Ni Wu , Cao Guangwen
Published: April 2023

Supplementary Figure 2. The effect of antiviral treatment on HCC occurrence and liver death in patients with one or more HBV mutations (C1653T, T1753V, and A1762T/G1764A) and those without any of the mutations. (A) HCC occurrence in patients with one or more HBV mutations; (B) HCC occurrence in patients without any of the 3 mutations; (C) liver death in patients with one or more HBV mutations; (D) liver death in patients without any of the 3 mutations. P values, log-rank test.
Supplementary Figure S3 from Assessment of Esophageal Adenocarcinoma Risk Using Somatic Chromosome Alterations in Longitudinal Samples in Barrett's Esophagus
Authors: Li Xiaohong , Paulson Thomas G. , Galipeau Patricia C. , Sanchez Carissa A. , Liu Karen , Kuhner Mary K. , Maley Carlo C. , Self Steven G. , Vaughan Thomas L. , Reid Brian J. , Blount Patricia L.
Published: April 2023

ROC for T1 using Jackknife method. The model was trained on T1 data with one sample left out and tested on the left out T1 sample (AUC=0.86). The ROC curve is established based on the testing results of the 248 left-out samples.
Supplementary Figure S1 from Assessment of Esophageal Adenocarcinoma Risk Using Somatic Chromosome Alterations in Longitudinal Samples in Barrett's Esophagus
Authors: Li Xiaohong , Paulson Thomas G. , Galipeau Patricia C. , Sanchez Carissa A. , Liu Karen , Kuhner Mary K. , Maley Carlo C. , Self Steven G. , Vaughan Thomas L. , Reid Brian J. , Blount Patricia L.
Published: April 2023

Processes applied for SCA feature selection, prediction model development and cross-validation in the study.
Supplemental Figures and Tables legends from Notch1 Mutations Are Drivers of Oral Tumorigenesis
Authors: Izumchenko Evgeny , Sun Kai , Jones Sian , Brait Mariana , Agrawal Nishant , Koch Wayne , McCord Christine L. , Riley David R. , Angiuoli Samuel V. , Velculescu Victor E. , Jiang Wei-Wen , Sidransky David
Published: April 2023

Supplemental Figures and Tables legends
Supplemental Figure 3 from Notch1 Mutations Are Drivers of Oral Tumorigenesis
Authors: Izumchenko Evgeny , Sun Kai , Jones Sian , Brait Mariana , Agrawal Nishant , Koch Wayne , McCord Christine L. , Riley David R. , Angiuoli Samuel V. , Velculescu Victor E. , Jiang Wei-Wen , Sidransky David
Published: April 2023

Supplemental Figure 3. A. Association between tumor stage of OSCC patients and NOTCH1 mutation-status. B. Table demonstrates differences in smoking and alcohol consumption rates between the OSCC and leukoplakia patients. C. Table demonstrates differences in smoking and alcohol consumption rates between the OSCC and leukoplakia lesions with mutated NOTCH1. D. The pattern of NOTCH1 base-pair mutations resulting from exposure to tobacco in OSCC and leukoplakia patients (in blue, base-pair mutations that found in both, smokers and non-smokers).
Supplementary Tables 1-5, Methods from Development of Dietary Phytochemical Chemopreventive Agents: Biomarkers and Choice of Dose for Early Clinical Trials
Authors: Scott Edwina N. , Gescher Andreas J. , Steward William P. , Brown Karen
Published: April 2023

Supplementary Tables 1-5, Methods from Development of Dietary Phytochemical Chemopreventive Agents: Biomarkers and Choice of Dose for Early Clinical Trials
Supplementary Table 2 from Development of Dietary Phytochemical Chemopreventive Agents: Biomarkers and Choice of Dose for Early Clinical Trials
Authors: Scott Edwina N. , Gescher Andreas J. , Steward William P. , Brown Karen
Published: April 2023

Supplementary Table 2 from Development of Dietary Phytochemical Chemopreventive Agents: Biomarkers and Choice of Dose for Early Clinical Trials
Table S2 from Phase II Drug-Metabolizing Polymorphisms and Smoking Predict Recurrence of Non–Muscle-Invasive Bladder Cancer: A Gene–Smoking Interaction
Authors: Lacombe Louis , Fradet Vincent , Lévesque Éric , Pouliot Frédéric , Larue Hélène , Bergeron Alain , Hovington Hélène , Caron André , Nguile-Makao Molière , Harvey Mario , Fradet Yves , Guillemette Chantal
Published: April 2023

Interaction between smoking (3 categories) and UGT1A1 genetic status (dominant model) in Cox multivariate model and the risk of bladder cancer recurrence.
Table S1 from Phase II Drug-Metabolizing Polymorphisms and Smoking Predict Recurrence of Non–Muscle-Invasive Bladder Cancer: A Gene–Smoking Interaction
Authors: Lacombe Louis , Fradet Vincent , Lévesque Éric , Pouliot Frédéric , Larue Hélène , Bergeron Alain , Hovington Hélène , Caron André , Nguile-Makao Molière , Harvey Mario , Fradet Yves , Guillemette Chantal
Published: April 2023

Baseline characteristics and relation to recurrence
Supplementary Methods, Figures 1-3 from Fluorinated COX-2 Inhibitors as Agents in PET Imaging of Inflammation and Cancer
Authors: Uddin Md. Jashim , Crews Brenda C. , Ghebreselasie Kebreab , Huda Imran , Kingsley Philip J. , Ansari Mohammad Sib , Tantawy Mohammed N. , Reese Jeffery , Marnett Lawrence J.
Published: April 2023

PDF file - 312K
Perspective on This Article from Fluorinated COX-2 Inhibitors as Agents in PET Imaging of Inflammation and Cancer
Authors: Uddin Md. Jashim , Crews Brenda C. , Ghebreselasie Kebreab , Huda Imran , Kingsley Philip J. , Ansari Mohammad Sib , Tantawy Mohammed N. , Reese Jeffery , Marnett Lawrence J.
Published: April 2023

Perspective on This Article from Fluorinated COX-2 Inhibitors as Agents in PET Imaging of Inflammation and Cancer
Supplementary Figure Legends from Improved Innate Immune Responses by Frondanol A5, a Sea Cucumber Extract, Prevent Intestinal Tumorigenesis
Authors: Janakiram Naveena B. , Mohammed Altaf , Bryant Taylor , Lightfoot Stan , Collin Peter D. , Steele Vernon E. , Rao Chinthalapally V.
Published: April 2023

Supplementary Figure Legends
SupplemMaterials and Methodsentary data from Improved Innate Immune Responses by Frondanol A5, a Sea Cucumber Extract, Prevent Intestinal Tumorigenesis
Authors: Janakiram Naveena B. , Mohammed Altaf , Bryant Taylor , Lightfoot Stan , Collin Peter D. , Steele Vernon E. , Rao Chinthalapally V.
Published: April 2023

Materials and Methods
Supplementary Figure S8 from St. John's Wort Attenuates Colorectal Carcinogenesis in Mice through Suppression of Inflammatory Signaling
Authors: Manna Soumen K. , Golla Srujana , Golla Jaya Prakash , Tanaka Naoki , Cai Yan , Takahashi Shogo , Krausz Kristopher W. , Matsubara Tsutomu , Korboukh Ilia , Gonzalez Frank J.
Published: April 2023

Supplementary Figure S8: Serum ALT (A) and ALP (B) level of mice on control, 2.5% and 5% St. John's wort extract supplemented diet. Statistical significance was calculated using oneway ANOVA with Tukey's correction for multiple testing.
Supplementary Figure S10 from St. John's Wort Attenuates Colorectal Carcinogenesis in Mice through Suppression of Inflammatory Signaling
Authors: Manna Soumen K. , Golla Srujana , Golla Jaya Prakash , Tanaka Naoki , Cai Yan , Takahashi Shogo , Krausz Kristopher W. , Matsubara Tsutomu , Korboukh Ilia , Gonzalez Frank J.
Published: April 2023

Supplementary Figure S10: Hematoxylin and Eosin-stained sections of colon from saline injected mice on control (Con/Sal) or St. John's wort-supplemented diet (SJW/Sal) and AOM injected mice on control (Con/AOM) or St. John's wort-supplemented diet (SJW/Sal) in the long-term study.
Supplementary Figure Legends from St. John's Wort Attenuates Colorectal Carcinogenesis in Mice through Suppression of Inflammatory Signaling
Authors: Manna Soumen K. , Golla Srujana , Golla Jaya Prakash , Tanaka Naoki , Cai Yan , Takahashi Shogo , Krausz Kristopher W. , Matsubara Tsutomu , Korboukh Ilia , Gonzalez Frank J.
Published: April 2023

Supplementary Figure Legends
Supplementary Info from Cancer-Specific Production of N-Acetylaspartate via NAT8L Overexpression in Non–Small Cell Lung Cancer and Its Potential as a Circulating Biomarker
Authors: Lou Tzu-Fang , Sethuraman Deepa , Dospoy Patrick , Srivastva Pallevi , Kim Hyun Seok , Kim Joongsoo , Ma Xiaotu , Chen Pei-Hsuan , Huffman Kenneth E. , Frink Robin E. , Larsen Jill E. , Lewis Cheryl , Um Sang-Won , Kim Duk-Hwan , Ahn Jung-Mo , DeBerardinis Ralph J. , White Michael A. , Minna John D. , Yoo Hyuntae
Published: April 2023

Chemical identification of MMG-L as N-acetylaspartate (NAA). Supplementary Methods Supplementary Figure Legends
Supplementary Figure 3 from Effects of Pubertal Exposure to Dietary Soy on Estrogen Receptor Activity in the Breast of Cynomolgus Macaques
Authors: Dewi Fitriya N. , Wood Charles E. , Willson Cynthia J. , Register Thomas C. , Lees Cynthia J. , Howard Timothy D. , Huang Zhiqing , Murphy Susan K. , Tooze Janet A. , Chou Jeff W. , Miller Lance D. , Cline J. Mark
Published: April 2023

Gene expression profile in the post-menarchal macaque breast by microarray. (A) Venn diagram showing number of genes that changed with time (i.e. between 7-12 months to 18-24 months after menarche) in the control (CL) and soy group (SOY), based on unadjusted P-values from a paired t-test in each diet group. (B) The list of top-10 genes that showed significant difference by dietary treatment using empirical Bayes statistics. (C) The top-10 significantly enriched KEGG pathways in CL and SOY groups across time. FC = fold-change; FDR=false discovery rate.
Supplementary Table 1 from Colon Tumors with the Simultaneous Induction of Driver Mutations in APC, KRAS, and PIK3CA Still Progress through the Adenoma-to-carcinoma Sequence
Authors: Hadac Jamie N. , Leystra Alyssa A. , Paul Olson Terrah J. , Maher Molly E. , Payne Susan N. , Yueh Alexander E. , Schwartz Alexander R. , Albrecht Dawn M. , Clipson Linda , Pasch Cheri A. , Matkowskyj Kristina A. , Halberg Richard B. , Deming Dustin A.
Published: April 2023

Characteristics of the mice treated with Adeno-Cre.
Supplementary Figure S3 from Colon Tumors with the Simultaneous Induction of Driver Mutations in APC, KRAS, and PIK3CA Still Progress through the Adenoma-to-carcinoma Sequence
Authors: Hadac Jamie N. , Leystra Alyssa A. , Paul Olson Terrah J. , Maher Molly E. , Payne Susan N. , Yueh Alexander E. , Schwartz Alexander R. , Albrecht Dawn M. , Clipson Linda , Pasch Cheri A. , Matkowskyj Kristina A. , Halberg Richard B. , Deming Dustin A.
Published: April 2023

Colonoscopic images over time, whole mount image and H&E-stained section of a tumor from a Apcfl/fl Pik3cap110* mouse inoculated with Adeno-Cre that spontaneously decreased in size.
Supplementary Figure S1 from Colon Tumors with the Simultaneous Induction of Driver Mutations in APC, KRAS, and PIK3CA Still Progress through the Adenoma-to-carcinoma Sequence
Authors: Hadac Jamie N. , Leystra Alyssa A. , Paul Olson Terrah J. , Maher Molly E. , Payne Susan N. , Yueh Alexander E. , Schwartz Alexander R. , Albrecht Dawn M. , Clipson Linda , Pasch Cheri A. , Matkowskyj Kristina A. , Halberg Richard B. , Deming Dustin A.
Published: April 2023

Urigential mass in a FC1 KrasG12D/+ Pik3cap110* mouse shown in situ, in whole mount and sectioned with H&E staining.
Supplementary Methods from Bacterial Prostatitis Enhances 2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]Pyridine (PhIP)–Induced Cancer at Multiple Sites
Authors: Sfanos Karen S. , Canene-Adams Kirstie , Hempel Heidi , Yu Shu-Han , Simons Brian W. , Schaeffer Anthony J. , Schaeffer Edward M. , Nelson William G. , De Marzo Angelo M.
Published: April 2023

Supplementary Methods file
Supplementary Figure Legends from Bacterial Prostatitis Enhances 2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]Pyridine (PhIP)–Induced Cancer at Multiple Sites
Authors: Sfanos Karen S. , Canene-Adams Kirstie , Hempel Heidi , Yu Shu-Han , Simons Brian W. , Schaeffer Anthony J. , Schaeffer Edward M. , Nelson William G. , De Marzo Angelo M.
Published: April 2023

Supplementary Figure Legends
Supplementary Fig. S4 from Bacterial Prostatitis Enhances 2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]Pyridine (PhIP)–Induced Cancer at Multiple Sites
Authors: Sfanos Karen S. , Canene-Adams Kirstie , Hempel Heidi , Yu Shu-Han , Simons Brian W. , Schaeffer Anthony J. , Schaeffer Edward M. , Nelson William G. , De Marzo Angelo M.
Published: April 2023

Supplementary Figure S4. IHC for E. coli in rat prostate tissues at 42 weeks post-inoculation.
Supplementary Tables 1-12 and Figures 1-3 from The Doylestown Algorithm: A Test to Improve the Performance of AFP in the Detection of Hepatocellular Carcinoma
Authors: Wang Mengjun , Devarajan Karthik , Singal Amit G. , Marrero Jorge A. , Dai Jianliang , Feng Ziding , Rinaudo Jo Ann S. , Srivastava Sudhir , Evans Alison , Hann Hie-Won , Lai Yinzhi , Yang Hushan , Block Timothy M. , Mehta Anand
Published: April 2023

Data description and detailed statistical information regarding model development. Supplementary Table 1. Patient information on samples from the University of Michigan. Supplementary Table 2. Patient information on samples from HALT-C. Supplementary Table 3. Patient information on samples from EDRN. Supplementary Table 4. Patient information on samples from Thomas Jefferson University. Supplementary Table 5. Patient information on samples from the University of Texas Southwestern Medical Center. Supplementary Table 6. Odds ratios for each predictor in univariate and multivariate logistic regressions. Supplementary Table 7. Indices of goodness-of-fit and apparent validation of candidate logistic regression models. Supplementary Table 8. Performance of leave one out cross validation (LOOCV). Supplementary Table 9. Cross Validation of bootstrap method. Supplementary Table 10. AUCs and IDIs from 3-fold Cross-Validation. Supplementary Table 11. Summary statistics of Doylestown model. Supplementary Table 12. Comparison of logistic regression, classification and regression tree (CART) and conditional inference tree (CTREE). Supplementary Figure 1. The distribution of AFP in each data set by cases and controls: Supplementary Figure 2. Quartiles for AFP in the individual patient sets. Supplementary Figure 3. Histogram of predictions and observe occurrence proportion of HCC for the top 4 models.
Supplementary Fig. S2 from Bacterial Prostatitis Enhances 2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]Pyridine (PhIP)–Induced Cancer at Multiple Sites
Authors: Sfanos Karen S. , Canene-Adams Kirstie , Hempel Heidi , Yu Shu-Han , Simons Brian W. , Schaeffer Anthony J. , Schaeffer Edward M. , Nelson William G. , De Marzo Angelo M.
Published: April 2023

Supplementary Figure S2. A single E. coli infection of the rat prostate induces long-term chronic inflammation that persists up to 42 weeks.
Supplementary Table 2. from Serum Glycans as Risk Markers for Non–Small Cell Lung Cancer
Authors: Ruhaak L. Renee , Stroble Carol , Dai Jianliang , Barnett Matt , Taguchi Ayumu , Goodman Gary E. , Miyamoto Suzanne , Gandara David , Feng Ziding , Lebrilla Carlito B. , Hanash Samir
Published: April 2023

Glycans that were identified to be significantly different between NSCLC cases and controls in the discovery set.
supplemental figure 1 from Low SFRP1 Expression Correlates with Poor Prognosis and Promotes Cell Invasion by Activating the Wnt/β-Catenin Signaling Pathway in NPC
Authors: Ren Xian-Yue , Zhou Guan-Qun , Jiang Wei , Sun Ying , Xu Ya-Fei , Li Ying-Qin , Tang Xin-Ran , Wen Xin , He Qing-Mei , Yang Xiao-Jing , Liu Na , Ma Jun
Published: April 2023

Supplemental Figure 1. The SFRP1 mRNA (A) and protein (B) expression of CNE-2 and SUNE-1 cells transfected with plasmid pcDNA3.1-SFRP1 compared to the original cell lines and the pcDNA3.1-vector.
Supplementary Materials from Enhanced Antitumor Effects of Novel Intracellular Delivery of an Active Form of Menaquinone-4, Menahydroquinone-4, into Hepatocellular Carcinoma
Authors: Setoguchi Shuichi , Watase Daisuke , Matsunaga Kazuhisa , Matsubara Misa , Kubo Yohei , Kusuda Mariko , Nagata-Akaho Nami , Enjoji Munechika , Nakashima Manabu , Takeshita Morishige , Karube Yoshiharu , Takata Jiro
Published: April 2023

Supplementary Materials. Supplementary Material and Methods, Results, References, and Figure legends.
Fig S6 from Loss of BRCA1 in the Cells of Origin of Ovarian Cancer Induces Glycolysis: A Window of Opportunity for Ovarian Cancer Chemoprevention
Authors: Chiyoda Tatsuyuki , Hart Peter C. , Eckert Mark A. , McGregor Stephanie M. , Lastra Ricardo R. , Hamamoto Ryuji , Nakamura Yusuke , Yamada S. Diane , Olopade Olufunmilayo I. , Lengyel Ernst , Romero Iris L.
Published: April 2023

Fig S6 shows low BRCA1 expression is associated with elevated HK2 and MYC in breast cancer cell lines.
Suppl. Figure 4 from Voluntary Wheel Running Reduces the Acute Inflammatory Response to Liver Carcinogen in a Sex-specific Manner
Authors: Bay M.L. , Gehl Julie , Pedersen Bente Klarlund , Hojman Pernille
Published: April 2023

Supplementary Figure 4. Hepatic protein expression of NF-kB.
Table S3 from Risk Prediction of Cervical Cancer and Precancers by Type-Specific Human Papillomavirus: Evidence from a Population-Based Cohort Study in China
Authors: Dong Li , Hu Shang-Ying , Zhang Qian , Feng Rui-Mei , Zhang Li , Zhao Xue-Lian , Zhang Xun , Qiao You-Lin , Zhao Fang-Hui
Published: April 2023

cumulative risk of CIN2+ in association with increasing positive times of type-specific hrHPV during 2005-2014.
Supplementary table 1 from Pigs, Unlike Mice, Have Two Distinct Colonic Stem Cell Populations Similar to Humans That Respond to High-Calorie Diet prior to Insulin Resistance
Authors: Charepalli Venkata , Reddivari Lavanya , Radhakrishnan Sridhar , Eriksson Elisabeth , Xiao Xia , Kim Sung Woo , Shen Frank , Vijay-Kumar Matam , Li Qunhua , Bhat Vadiraja B. , Knight Rob , Vanamala Jairam K.P.
Published: April 2023

Supplementary table 1 shows body weight, daily weight gain and feed intake data.
Supplementary Tables 1 and 2 from Screening of Chemopreventive Agents in Animal Models: Results on Reproducibility, Agents of a Given Class, and Agents Tested During Tumor Progression
Authors: Lubet Ronald A. , Steele Vernon E. , Shoemaker Robert H. , Grubbs Clinton J.
Published: April 2023

Supplementary Table 1. Characteristics and Response to Agents of the Animal Models Employed In this Paper. Supplementary Table 2. Materials Relating to Reproducibility of Suboptimal Doses [ppm (mg/kg diet) or mg/Kg BW/day, i.g]
Supplementary Figure 1 from Screening of Chemopreventive Agents in Animal Models: Results on Reproducibility, Agents of a Given Class, and Agents Tested During Tumor Progression
Authors: Lubet Ronald A. , Steele Vernon E. , Shoemaker Robert H. , Grubbs Clinton J.
Published: April 2023

Chemical Structures of Classes of Effective Agents
Figures for Supplementary Figures 1-7 from Unlocking Aspirin's Chemopreventive Activity: Role of Irreversibly Inhibiting Platelet Cyclooxygenase-1
Authors: Lichtenberger Lenard M. , Fang Dexing , Bick Roger J. , Poindexter Brian J. , Phan Tri , Bergeron Angela L. , Pradhan Subhashree , Dial Elizabeth J. , Vijayan K. Vinod
Published: April 2023

Figure legends for Supplementary Figures 1-7.
Supplementary Figure 3 from A Prospective Targeted Serum Metabolomics Study of Pancreatic Cancer in Postmenopausal Women
Authors: Jiao Li , Maity Suman , Coarfa Cristian , Rajapakshe Kimal , Chen Liang , Jin Feng , Putluri Vasanta , Tinker Lesley F. , Mo Qianxing , Chen Fengju , Sen Subrata , Sangi-Hyghpeykar Haleh , El-Serag Hashem B. , Putluri Nagireddy
Published: April 2023

Supplemental figure 3
Supplemental data from Activation of TRPA1 Channel by Antibacterial Agent Triclosan Induces VEGF Secretion in Human Prostate Cancer Stromal Cells
Authors: Derouiche Sandra , Mariot Pascal , Warnier Marine , Vancauwenberghe Eric , Bidaux Gabriel , Gosset Pierre , Mauroy Brigitte , Bonnal Jean-Louis , Slomianny Christian , Delcourt Philippe , Dewailly Etienne , Prevarskaya Natalia , Roudbaraki Morad
Published: April 2023

Supplemental Figure S1. TCS-induced calcium entry is similar to TRPA1 ligand activated calcium entry. Supplemental Figure S2 and S3 . Inhibitory efficacy of different known TRPA1 inhibitors on TCS-induced calcium entry in PrSC cells. Supplemental Figure S4. Inhibitory efficacy of different known TRPA1 inhibitors on TCS-induced VEGF secretion by PrSC cells.
Supplementary Figure S4 from Fusobacterium Nucleatum Subspecies Animalis Influences Proinflammatory Cytokine Expression and Monocyte Activation in Human Colorectal Tumors
Authors: Ye Xiangcang , Wang Rui , Bhattacharya Rajat , Boulbes Delphine R. , Fan Fan , Xia Ling , Adoni Harish , Ajami Nadim J. , Wong Matthew C. , Smith Daniel P. , Petrosino Joseph F. , Venable Susan , Qiao Wei , Baladandayuthapani Veera , Maru Dipen , Ellis Lee M.
Published: April 2023

Expression of CCL20 in human CRC cell lines and THP-1 monocytes induced by co-culture with F. nucleatum ssp.
Supplementary Figure S2 from Fusobacterium Nucleatum Subspecies Animalis Influences Proinflammatory Cytokine Expression and Monocyte Activation in Human Colorectal Tumors
Authors: Ye Xiangcang , Wang Rui , Bhattacharya Rajat , Boulbes Delphine R. , Fan Fan , Xia Ling , Adoni Harish , Ajami Nadim J. , Wong Matthew C. , Smith Daniel P. , Petrosino Joseph F. , Venable Susan , Qiao Wei , Baladandayuthapani Veera , Maru Dipen , Ellis Lee M.
Published: April 2023

Identification of Fusobacterium spp. and subspecies in human colorectal tumors using Fusobacterium genus 16S V2 - V4 amplicon cloning and sequencing, as well as amplicon-targeted direct sequencing
Supplementary Figure S1 from Fusobacterium Nucleatum Subspecies Animalis Influences Proinflammatory Cytokine Expression and Monocyte Activation in Human Colorectal Tumors
Authors: Ye Xiangcang , Wang Rui , Bhattacharya Rajat , Boulbes Delphine R. , Fan Fan , Xia Ling , Adoni Harish , Ajami Nadim J. , Wong Matthew C. , Smith Daniel P. , Petrosino Joseph F. , Venable Susan , Qiao Wei , Baladandayuthapani Veera , Maru Dipen , Ellis Lee M.
Published: April 2023

Identification of Fusobacterium spp. in normal colorectal mucosal and tumor specimens.
Supplementary Figure Legends from Fusobacterium Nucleatum Subspecies Animalis Influences Proinflammatory Cytokine Expression and Monocyte Activation in Human Colorectal Tumors
Authors: Ye Xiangcang , Wang Rui , Bhattacharya Rajat , Boulbes Delphine R. , Fan Fan , Xia Ling , Adoni Harish , Ajami Nadim J. , Wong Matthew C. , Smith Daniel P. , Petrosino Joseph F. , Venable Susan , Qiao Wei , Baladandayuthapani Veera , Maru Dipen , Ellis Lee M.
Published: April 2023

Supplementary Figure Legends describe the identification of Fusobacterium by an alternative method and confirmation of CCL20 protein expression by ELISA and functional assays in additional cell lines.
Supplement2 from Fallopian Tube Lesions in Women at High Risk for Ovarian Cancer: A Multicenter Study
Authors: Visvanathan Kala , Shaw Patricia , May Betty J. , Bahadirli-Talbott Asli , Kaushiva Alpana , Risch Harvey , Narod Steven , Wang Tian-Li , Parkash Vinita , Vang Russell , Levine Douglas A. , Soslow Robert , Kurman Robert , Shih Ie-Ming
Published: April 2023

Supplement 2
Supplement 3 from Fallopian Tube Lesions in Women at High Risk for Ovarian Cancer: A Multicenter Study
Authors: Visvanathan Kala , Shaw Patricia , May Betty J. , Bahadirli-Talbott Asli , Kaushiva Alpana , Risch Harvey , Narod Steven , Wang Tian-Li , Parkash Vinita , Vang Russell , Levine Douglas A. , Soslow Robert , Kurman Robert , Shih Ie-Ming
Published: April 2023

Supplement 3: Baseline characteristics for the 105 women that underwent extensive sampling of the

fallopian tube.
Supplemental Figure Legend from The Prolyl Isomerase Pin1 Is a Novel Target of 6,7,4′-Trihydroxyisoflavone for Suppressing Esophageal Cancer Growth
Authors: Lim Tae-Gyu , Lee Sung-Young , Duan Zhaoheng , Lee Mee-Hyun , Chen Hanyong , Liu Fangfang , Liu Kangdong , Jung Sung Keun , Kim Dong Joon , Bode Ann M. , Lee Ki Won , Dong Zigang
Published: April 2023

Supplemental Figure Legend
Supplemental Figure 1 from The Prolyl Isomerase Pin1 Is a Novel Target of 6,7,4′-Trihydroxyisoflavone for Suppressing Esophageal Cancer Growth
Authors: Lim Tae-Gyu , Lee Sung-Young , Duan Zhaoheng , Lee Mee-Hyun , Chen Hanyong , Liu Fangfang , Liu Kangdong , Jung Sung Keun , Kim Dong Joon , Bode Ann M. , Lee Ki Won , Dong Zigang
Published: April 2023

6,7,4'-THIF does not bind to FKBP or cyclophilin A. The interaction between 6,7,4'-THIF and FKBP or cyclophilin A was confirmed using 6,7,4'-THIF-Sepharose 4B beads. 6,7,4'-THIF-Sepharose 4B beads were incubated with each cell lysate overnight. Total experimental procedures are described in Materials and Methods.
Supplementary Figure S1 from The Second-Generation PGI2 Analogue Treprostinil Fails to Chemoprevent Tumors in a Murine Lung Adenocarcinoma Model
Authors: Dwyer-Nield Lori , Hickey Gregory A. , Friedman Micah , Choo Kevin , McArthur Debbie G. , Tennis Meredith A. , New Melissa L. , Geraci Mark , Keith Robert L.
Published: April 2023

Figure S1 shows that treprostinil exposure did not affect BAL cell number or BAL prostaglandin levels.
Supplemental Figure 5 from β-Carotene 9′,10′ Oxygenase Modulates the Anticancer Activity of Dietary Tomato or Lycopene on Prostate Carcinogenesis in the TRAMP Model
Authors: Tan Hsueh-Li , Thomas-Ahner Jennifer M. , Moran Nancy E. , Cooperstone Jessica L. , Erdman John W. , Young Gregory S. , Clinton Steven K.
Published: April 2023

SV40 expression.
Supplemental Figure 4 from β-Carotene 9′,10′ Oxygenase Modulates the Anticancer Activity of Dietary Tomato or Lycopene on Prostate Carcinogenesis in the TRAMP Model
Authors: Tan Hsueh-Li , Thomas-Ahner Jennifer M. , Moran Nancy E. , Cooperstone Jessica L. , Erdman John W. , Young Gregory S. , Clinton Steven K.
Published: April 2023

Distribution of highest pathologic grade.
Supplemental Figure S1 from Piperlongumine Induces Reactive Oxygen Species (ROS)-Dependent Downregulation of Specificity Protein Transcription Factors
Authors: Karki Keshav , Hedrick Erik , Kasiappan Ravi , Jin Un-Ho , Safe Stephen
Published: April 2023

The cancer cell lines were treated as outlined in Figure 3 and Annexin V staining was determined as described in the Materials and Methods.
Supplementary Table 4 from Bioactivity of Oral Linaclotide in Human Colorectum for Cancer Chemoprevention
Authors: Weinberg David S. , Lin Jieru E. , Foster Nathan R. , Della'Zanna Gary , Umar Asad , Seisler Drew , Kraft Walter K. , Kastenberg David M. , Katz Leo C. , Limburg Paul J. , Waldman Scott A.
Published: April 2023

Cyclic GMP responses in transverse colon biopsies in subjects receiving linaclotide (Active) or placebo.
Supplementary Table from Randomized Phase II Trial of Polyphenon E versus Placebo in Patients at High Risk of Recurrent Colonic Neoplasia
Authors: Sinicrope Frank A. , Viggiano Thomas R. , Buttar Navtej S. , Song Louis M. Wong Kee , Schroeder Kenneth W. , Kraichely Robert E. , Larson Mark V. , Sedlack Robert E. , Kisiel John B. , Gostout Christopher J. , Kalaiger Abdul M. , Patai Árpád V. , Della'Zanna Gary , Umar Asad , Limburg Paul J. , Meyers Jeffrey P. , Foster Nathan R. , Yang Chung S. , Sontag Stephen
Published: April 2023

Supplementary Table 1
Supplementary Tables 1-7 from Change in Blood and Benign Breast Biomarkers in Women Undergoing a Weight-Loss Intervention Randomized to High-Dose ω-3 Fatty Acids versus Placebo
Authors: Fabian Carol J. , Befort Christie A. , Phillips Teresa A. , Nydegger Jennifer L. , Kreutzjans Amy L. , Powers Kandy R. , Metheny Trina , Klemp Jennifer R. , Carlson Susan E. , Sullivan Debra K. , Zalles Carola M. , Giles Erin D. , Hursting Stephen D. , Hu Jinxiang , Kimler Bruce F.
Published: April 2023

Supplemental Table 1: Specimen collection and assay methods details. Supplemental Table 2 Adverse Events Supplemental Table 3. Value and changes in ratio of (DHA+EPA)/AA in erythrocyte phospholipids. Supplemental Table 4. Median relative difference (percent) between baseline and 12 months for 19 serum biomarkers (of a total of 24 assessed) which exhibited a statistically significant change over time* either for the total cohort of 35 women completing the 12-month trial and/or for groups defined by randomization or by dichotomization at 10% weight loss achieved at 6 months. Supplemental Table 5: Biomarker change at 12 months by subgroups defined by randomization arm (placebo vs Ï‰-3 FA) and dichotomization by weight loss (<10% or >10%). Biomarkers are grouped into categories of adipokines, cytokines, hormones/growth factors, and insulin. A total of 24 biomarkers or ratios were assessed at 12 months. Supplemental Table 6: Levels and changes for adiponectin assessed in serum collected both fasting and non-fasting, and in benign breast tissue acquired non-fasting by RPFNA. Supplemental Table 7: Baseline, 6-month, and 12-month values and change over time for Ki-67, Masood cytomorphology score. -
Supplementary Table 1 from Alterations of Cyclooxygenase-2 Methylation Levels Before and After Intervention Trial to Prevent Gastric Cancer in a Chinese Population
Authors: Zhang Yang , Zeng Hong-Mei , Nie Xiao-Rui , Zhang Lian , Ma Jun-Ling , Li Ji-You , Pan Kai-Feng , You Wei-Cheng
Published: April 2023

The association of evolutions of Ind DYS/DYS subjects with COX-2 expression changes.
Supplementary Data legends from Prevention of Tobacco Carcinogen-Induced Lung Tumor Development by a Novel STAT3 Decoy Inhibitor
Authors: Njatcha Christian , Farooqui Mariya , Almotlak Abdulaziz A. , Siegfried Jill M.
Published: April 2023

Supplementary Figure legends
Supplementary Data from Prevention of Lipid Peroxidation–derived Cyclic DNA Adduct and Mutation in High-Fat Diet–induced Hepatocarcinogenesis by Theaphenon E
Authors: Coia Heidi , Ma Ning , Hou Yanqi , Dyba Marcin D. , Fu Ying , Cruz M. Idalia , Benitez Carlos , Graham Garrett T. , McCutcheon Justine N. , Zheng Yun-Ling , Sun Bing , Kallakury Bhaskar V. , Ma Junfeng , Fang Hong-Bin , Berry Deborah L. , Muralidaran Vinona , Chung Fung-Lung
Published: April 2023

Supplementary tables and figures for study
Supplemental Table 4 from Influence of Obesity on Breast Density Reduction by Omega-3 Fatty Acids: Evidence from a Randomized Clinical Trial
Authors: Sandhu Narinder , Schetter Susann E. , Liao Jason , Hartman Terryl J. , Richie John P. , McGinley John , Thompson Henry J. , Prokopczyk Bogdan , DuBrock Cynthia , Signori Carina , Hamilton Christopher , Calcagnotto Ana , Trushin Neil , Aliaga Cesar , Demers Laurence M. , El-Bayoumy Karam , Manni Andrea
Published: April 2023

Effects of Raloxifene and/or Lovaza on Relative Plasma Fatty Acid Concentration.
Supplemental Table 2 from Influence of Obesity on Breast Density Reduction by Omega-3 Fatty Acids: Evidence from a Randomized Clinical Trial
Authors: Sandhu Narinder , Schetter Susann E. , Liao Jason , Hartman Terryl J. , Richie John P. , McGinley John , Thompson Henry J. , Prokopczyk Bogdan , DuBrock Cynthia , Signori Carina , Hamilton Christopher , Calcagnotto Ana , Trushin Neil , Aliaga Cesar , Demers Laurence M. , El-Bayoumy Karam , Manni Andrea
Published: April 2023

Correlation between baseline demographics and percent versus absolute breast density with and without adjustment for BMI.
Supplementary Table 2 from Bacterial Vaginosis Decreases the Risk of Cervical Cytological Abnormalities
Authors: Long Tengfei , Zhang Chao , He Gui , Hu Yue , Lin Zhongqiu , Long Lingli
Published: April 2023

Supplementary Table 2: Univariate regression analysis by age among CA, HPV, VVC and BV infection groups
Supplementary Tables from Combination of Sulindac and Bexarotene for Prevention of Intestinal Carcinogenesis in Familial Adenomatous Polyposis
Authors: Bowen Charles M. , Walter Lewins , Borras Ester , Wu Wenhui , Ozcan Zuhal , Chang Kyle , Bommi Prashant V. , Taggart Melissa W. , Thirumurthi Selvi , Lynch Patrick M. , Reyes-Uribe Laura , Scheet Paul A. , Sinha Krishna M. , Vilar Eduardo
Published: April 2023

Supplementary Tables S1-S4
Supplementary Figures from Combination of Sulindac and Bexarotene for Prevention of Intestinal Carcinogenesis in Familial Adenomatous Polyposis
Authors: Bowen Charles M. , Walter Lewins , Borras Ester , Wu Wenhui , Ozcan Zuhal , Chang Kyle , Bommi Prashant V. , Taggart Melissa W. , Thirumurthi Selvi , Lynch Patrick M. , Reyes-Uribe Laura , Scheet Paul A. , Sinha Krishna M. , Vilar Eduardo
Published: April 2023

Supplementary Figures S1-S5
Table S1 from PROgesterone Therapy for Endometrial Cancer Prevention in Obese Women (PROTEC) Trial: A Feasibility Study
Authors: Derbyshire Abigail E. , Allen Jennifer L. , Gittins Matthew , Lakhiani Bhavna , Bolton James , Shaw Joseph , Pemberton Philip W. , Needham Michelle , MacKintosh Michelle L. , Edmondson Richard J. , Kitchener Henry C. , Crosbie Emma J.
Published: April 2023

Immunohistochemical antibodies and protocols
Supplementary File 2 from Analysis of the Transcriptome: Regulation of Cancer Stemness in Breast Ductal Carcinoma In Situ by Vitamin D Compounds
Authors: Shan Naing Lin , Minden Audrey , Furmanski Philip , Bak Min Ji , Cai Li , Wernyj Roman , Sargsyan Davit , Cheng David , Wu Renyi , Kuo Hsiao-Chen D. , Li Shanyi N. , Fang Mingzhu , Maehr Hubert , Kong Ah-Ng , Suh Nanjoo
Published: April 2023

Excel file 2
Figure S2 from Persistence of Bronchial Dysplasia Is Associated with Development of Invasive Squamous Cell Carcinoma
Authors: Merrick Daniel T. , Gao Dexiang , Miller York E. , Keith Robert L. , Baron Anna E. , Feser William , Kennedy Timothy C. , Blatchford Patrick J. , Braudrick Sarah , Hirsch Fred R. , Heasley Lynn , Bunn Paul A. , Franklin Wilbur A.
Published: April 2023

Supplemental figure S2. Univariable analysis comparing frequency of SCC in cases grouped by highest baseline (BL) histology score (HS) or mean baseline histology score using a cutoff of HS > 5 (moderate dysplasia).
Table S3 from Association of Common Use Pharmaceuticals in Reducing Risk of Esophageal Adenocarcinoma: A SEER–Medicare Analysis
Authors: Loomans-Kropp Holli A. , Chaloux Matthew , Richmond Ellen , Umar Asad
Published: April 2023

Matched demographics of the selected SEER-Medicare population.
Supplementary Figure 2 from Stress-induced Norepinephrine Downregulates CCL2 in Macrophages to Suppress Tumor Growth in a Model of Malignant Melanoma
Authors: Steinberger Kayla J. , Bailey Michael T. , Gross Amy C. , Sumner Laura A. , Voorhees Jeffrey L. , Crouser Nisha , Curry Jennifer M. , Wang Yijie , DeVries A. Courtney , Marsh Clay B. , Glaser Ronald , Yang Eric V. , Eubank Timothy D.
Published: April 2023

Stress correlates with reduced tumor size and burden, VEGF and CCL2 levels, and infiltrating macrophages compared to unstressed mice.
Supplemental Figure Legends from Suppression of Colon Tumorigenesis in Mutant Apc Mice by a Novel PDE10 Inhibitor that Reduces Oncogenic β-Catenin
Authors: Lee Kevin J. , Chang Wen-Chi L. , Chen Xi , Valiyaveettil Jacob , Ramirez-Alcantara Veronica , Gavin Elaine , Musiyenko Alla , Madeira da Silva Luciana , Annamdevula Naga S. , Leavesley Silas J. , Ward Antonio , Mattox Tyler , Lindsey Ashley S. , Andrews Joel , Zhu Bing , Wood Charles , Neese Ashleigh , Nguyen Ashley , Berry Kristy , Maxuitenko Yulia , Moyer Mary Pat , Nurmemmedov Elmar , Gorman Greg , Coward Lori , Zhou Gang , Keeton Adam B. , Cooper Harry S. , Clapper Margie L. , Piazza Gary A.
Published: April 2023

Supplemental Figure Legends
Final Supplemental figures from β-Cryptoxanthin Reduced Lung Tumor Multiplicity and Inhibited Lung Cancer Cell Motility by Downregulating Nicotinic Acetylcholine Receptor α7 Signaling
Authors: Iskandar Anita R. , Miao Benchun , Li Xinli , Hu Kang-Quan , Liu Chun , Wang Xiang-Dong
Published: April 2023

Supplementary Figure S1. Reduction of mRNA expressions of α7-nachr by BCX supplementation, not α3-, α5-, and β4-nachr, was associated with lung tumor multiplicity. Upper panel: The statistically significant correlation between lung tumor multiplicity (tumor number) and the expression of nachr-α7 mRNA (P = 0.03, r = 0.394, Pearson's correlation) and α7-nAChR protein (P < 0.01, r = 0.355, Pearson's correlation). Bottom panel: There were no significant differences in the nachr-α3, nachr-α5, and nachr-β4 mRNA levels among all the groups. The mRNA levels were measured with quantitative reverse transcription polymerase chain reaction (qRT-PCR) and were normalized to the levels of GAPDH mRNA levels. The columns represent the mean {plus minus} sem. Abbreviation: BCX(1): β-cryptoxanthin 1 mg/kg diet; BCX(10): β-cryptoxanthin 10 mg/kg diet; NNK: 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. Supplementary Figure S2. BCX supplementation was associated with reduced early growth response-1 (Egr1) mRNA in the NNK-treated mice. The mRNA levels of egr1 were measured with quantitative reverse transcription polymerase chain reaction (qRT-PCR) and were normalized to the levels of GAPDH mRNA levels. The columns represent the mean {plus minus} sem. * P = 0.04. Dotted lines indicated significant decreasing levels in a BCX-dose dependent manner (P-linear trend = 0.05). Abbreviation: BCX (1): β-cryptoxanthin 1 mg/kg diet; BCX (10): β-cryptoxanthin 10 mg/kg diet; egr1: early growth response-1; NNK: 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. Supplementary Figure S3. PI3K downstream Rac1 and ARF6 contribute to lamellipodia suppression by BCX. BEAS-2B cells were transfected with wild type Rac1 or ARF6. Then cells were treated with BCX (1.0, 2.0, 4.0 μM) or MG624 (1.0 μM) for 12 hr. Cells were stained with TRITC-labeled phalloidin and analyzed using fluorescent microscopy. The representative fluorescent images are shown (A, the lamellipodia are indicated by arrowheads). The number of cells with significant lamellipodia was counted in five random fields (C). The representative fluorescent images of BEAS-2B cells were transfected with Rac1-Q61L or ARF6-Q67L are shown (B, the lamellipodia are indicated by arrowheads). The number of cells with significant lamellipodia was counted in five random fields (D). Results of Scratch wound are displayed in (E). *P = 0.04, **P = 0.01 compared with control group.
Supplemental Figure 4A from Suppression of Colon Tumorigenesis in Mutant Apc Mice by a Novel PDE10 Inhibitor that Reduces Oncogenic β-Catenin
Authors: Lee Kevin J. , Chang Wen-Chi L. , Chen Xi , Valiyaveettil Jacob , Ramirez-Alcantara Veronica , Gavin Elaine , Musiyenko Alla , Madeira da Silva Luciana , Annamdevula Naga S. , Leavesley Silas J. , Ward Antonio , Mattox Tyler , Lindsey Ashley S. , Andrews Joel , Zhu Bing , Wood Charles , Neese Ashleigh , Nguyen Ashley , Berry Kristy , Maxuitenko Yulia , Moyer Mary Pat , Nurmemmedov Elmar , Gorman Greg , Coward Lori , Zhou Gang , Keeton Adam B. , Cooper Harry S. , Clapper Margie L. , Piazza Gary A.
Published: April 2023

NMR of ADT 061.