bluuebunny/crossref_metadata_2025 huggingface dataset:
Latest Topics Concerning Cognitive Impairment Related with Olive Oil, Fruits, Vegetables and Others
Authors: Bando Masahiro , Urasaki Hirohisa , Bando Hiroshi
Published: July 2024

The authors focused on nutritional therapy, including low carbohydrate diets (LCD), calorie restriction (CR), lipids, olive oil, and other dietary studies. Recent topics on cognitive impairment related to olive oil, fruits, vegetables, and other factors were described with perspectives. A reverse relationship was observed between total fruit/vegetable intake and dementia risk in the elderly. In a study of 92,383 cases, an intake of more than 7g/day of olive oil showed a 28% decreased risk of dementia-related death. Dietary patterns may influence cognitive mechanisms. Among 8,692 elderly participants, lower odds ratios (OR) for cognitive impairment were found for a protein-enriched diet (PED) at 0.910 and an anti-inflammatory diet (AID) at 0.789.
Analysis of Influencing Factors for Chronic Low Back Pain with Cognitive Impairment
Authors: Su Ying
Published: July 2024

Background: Cognitive impairment (CI) is a common complication in chronic low back pain (CLBP) patients, and its progression increases the risk of dementia. However, there is currently a lack of predictive indicators for CLBP-CI. Previous studies have shown that routine blood indexes have predictive value for Alzheimer’s disease, but their relationship with CLBP-CI remains unclear. This study aims to explore the correlation between routine blood indexes and provide evidence of disparities in chronic pain and cognitive impairment between two groups of individuals with low back pain, as well as establish the foundation for longitudinal experimental studies aimed at developing effective interventions for cognitive impairment in individuals with chronic low back pain.
Methods: This cross-sectional study was conducted at West China Hospital, Sichuan University. The Montreal Cognitive Assessment (MoCA) was conducted to divide patients into the CLBP-CI or CLBP-nCI group. Statistical analysis was performed to examine the differences between chronic low back pain patients with cognitive impairment and those without cognitive impairment. All statistical tests were conducted at a significance level of α=0.05 for two-sided testing.
Results: The prevalence of chronic low back pain with cognitive impairment in this study demonstrates age-related disparities, with a higher prevalence observed among older individuals (P=0.009). A statistically significant difference in white blood cell count was observed between individuals with chronic low back pain and cognitive impairment (P=0.004).
Conclusion: Age and white blood cell count may serve as influential factors in the development of chronic low back pain with cognitive impairment. This finding can aid healthcare professionals in implementing early intervention and treatment for individuals experiencing this condition.
A Successful Endotracheal Intubation of a Patient with Ankylosing Spondylitis: A Case Report
Authors: Tu Hong
Published: July 2024

Background: Ankylosing spondylitis (AS) is a chronic inflammatory disorder that primarily affects the spine and eventually causes its malformation. Surgery is a common treatment for AS patients. Patients with severe AS usually have difficulty with ventilation or intubation. Therefore, airway management should be carefully evaluated, especially in patients with severe cervical deformities. Anesthesiologists must fully and carefully evaluate the airway in these patients.
Case Presentation: A 49-year-old woman with AS suffered from a severe spinal deformity that required surgical treatment under general anesthesia. The patient was monitored for vital signs and adequately oxygenated. Lidocaine was used for cricothyroid puncture and throat anesthesia. The feasibility of tracheal intubation was assessed using a visual laryngoscope to expose the glottis under full surface anesthesia. Finally, a #7 enhanced tracheal catheter was successfully inserted after conventional sequential induction. The surgery was successfully completed, and the patient was discharged 10 days after surgery.
Conclusions: Anesthesiologists should fully and carefully assess the presence of a difficult airway in patients with AS, whether it is difficult to ventilate or intubate. Adequate preparation plans are essential.
Case Report: Abnormal Movements of the Tongue Years after Tonsillar Cancer Treatment
Authors: Bhatia Sahibjot , Gahoonia Nimrit , Goswami Kartik , Yakhchalian Pegah , Pantera Richard
Published: July 2024

This case describes a 52-year-old female who presented with abnormal movements of the left side of her tongue. The patient was diagnosed with radiation induced myokymia of the tongue. This diagnosis was established based on history and exam findings, while also ruling out the original concern of recurrence of her tonsillar cancer using MRI imaging. The standard for diagnosing myokymia is through the use of electromyographic studies, however this study was not possible with the resources at the hospital.
Relative and Temporal Efficacy of the First and Second Covid 19 Booster Vaccine (3rd And 4th Dose) to Prevent Symptomatic Infection from December 2021 to October 2023 in a General Medicine Office in Toledo (Spain)
Authors: Turabian Jose Luis
Published: July 2024

Background: The effectiveness of COVID-19 vaccines in preventing serious infection and death is established, but their protection against infection is less certain. Additionally, their effectiveness diminishes over time. Furthermore, the evolution of the effectiveness of different booster doses of the vaccine against COVID-19, to prevent symptomatic infection in real life during the pandemic and the subsequent endemic, is not clearly documented.
Objective: To compare the effectiveness of the 3rd and 4th vaccine boosters against COVID-19 in preventing symptomatic COVID-19 infection during both the pandemic and the subsequent endemic phase.
Methodology: A comparative secondary analysis of the vaccine’s effectiveness against symptomatic COVID-19 infection (calculated as: 1 – (COVID-19 cases with vaccine doses / COVID-19 cases without vaccine dose) × 100) based on a prospective study from December 2021 to October 2023 in a general medicine office was conducted. The first booster dose was administered with monovalent mRNA vaccines, and the second booster with bivalent mRNA vaccines.
Results: From December 2021 to February 2022, the effectiveness of the primer vaccine booster was 60% when administered >= 15 days versus <15 days before infection, and 36% when administered >= 29 days versus < 29 days before infection. From October 2022 to February 2023, the effectiveness of the vaccine’s 4th dose was 84%. From October 2022 to October 2023, the effectiveness of the 4th dose of bivalent mRNA vaccine in preventing reinfections was 30%.
Conclusion: In the general practice setting in Toledo, Spain, the effectiveness of the first booster with mRNA vaccines against SARS-CoV-2 primary infection and symptomatic COVID-19 waned over time, but protection remained high with the second bivalent booster. However, the booster vaccine’s effectiveness is more modest in preventing symptomatic reinfections. Overall, completing the booster vaccination is worthwhile.
Recommended Diet Therapy of Mediterranean Diet (MD) and Low Carbohydrate Diet (LCD)
Authors: Bando Hiroshi
Published: July 2024

To maintain health and achieve longevity, an adequate diet is crucial, such as the Mediterranean diet (MD) and the low-carbohydrate diet (LCD). The MD is characterized by whole grains, fruits, vegetables, less red meat, more fish, and four eggs per week. The MD may reduce the risk of heart disease, stroke, dementia, and depression. The LCD shows remarkable weight reduction in a short period, but there may be a probable rebound effect within six months. In Japanese cuisine, the intake of fermented soy foods such as natto and miso can lower the risk of death. As a recommendation, the LCD can be started first, followed by the MD for the long term.
Automated LPG Monitoring and Rebooking System using IoT- A Review
Authors: S. Rajkumar , S. Venkatanathan , P. Prasanth
Published: August 2024

LPG (Liquified Petroleum Gas) has become an essential requirement in daily life, as many people rely on it for cooking, fueling vehicles, and more LPG offers a portable, clean, and efficient alternative to traditional fossil fuels, making it especially valuable for rural and urban areas in India. By replacing wood, coal, and other traditional fuels, LPG enhances health, air quality, and overall comfort. To simplify the LPG rebooking process for domestic and commercial use, various applications have been developed. This study presents a brief overview of existing research on LPG monitoring systems and proposes a method for automatic rebooking by monitoring LPG consumption in real-time and triggering an automatic refill request when the gas level reaches a predefined threshold. The system also provides users with notifications and updates about the status of the LPG, further enhancing convenience and reliability.
Efeitos do uso prolongado de benzodiazepínicos no surgimento da Doença de Alzheimer
Authors: Cardoso Cicuto Bruna Eduarda , Lazzarini Bulla Leticia , Thales de Souza Bezerra Raphael , Mafra de Oliveira Ítalo , Azevedo Guerra Yago , Vanessa Bandeira de Araújo Cavalcanti Amanda , Nogueira Araújo Rafaela , Lazzari Branquinho Paula , Ayres Vilela Joana , Mochi Brandão Leticia
Published: July 2024

Este trabalho investiga a relação entre o uso prolongado de benzodiazepínicos e a doença de Alzheimer, uma das formas mais prevalentes de demência na população idosa. Revisando a literatura atual, foram explorados os potenciais impactos cognitivos desses medicamentos, destacando-se os riscos associados, como alterações neuroquímicas, disfunções cognitivas e aumento da mortalidade em pacientes com Alzheimer. A análise abordou evidências epidemiológicas variadas sobre essa associação complexa, enfatizando a necessidade de mais pesquisas para compreender melhor fatores como dose, duração do uso e características individuais que podem modular esses riscos. Além disso, discutiu-se a importância de alternativas terapêuticas seguras, medidas preventivas e educação para pacientes e profissionais de saúde.
Abordagens no Tratamento de Queimaduras Graves: Uma Revisão dos Últimos 10 Anos
Authors: Cabellino Luíza Fricks , Oliveira Vimercati Jhennifer , Cazotti Thiengo Pedro Gabriel , Da Silva Gabriel Vinicius , Tozzi Fedrigo Tulio , Dias Nogueira Da Cruz Ana Alice , Da Silva Castro Rodrigues Naiana , De Almeida Zuppo Victória , Xaubet Burin Francis
Published: July 2024

Queimaduras, que podem variar de leves a graves, exigem tratamentos especializados para minimizar danos e promover a recuperação. Os curativos de prata, utilizados há séculos, são eficazes na redução de infecções devido às suas propriedades antimicrobianas, atuando contra a respiração e replicação bacteriana. A prata nanocristalina, que libera prata continuamente por 3 a 7 dias, reduz a frequência de trocas e o desconforto, enquanto a sulfadiazina de prata requer trocas diárias. O laser de CO2 fracionado é inovador no tratamento de queimaduras, melhorando a textura da pele, reduzindo contraturas e estimulando a produção de colágeno, beneficiando a recuperação estética e emocional dos pacientes. O ácido hialurônico acelera a cicatrização, melhora a elasticidade e densidade microvascular, e possui ação anti-inflamatória, prevenindo cicatrizes hipertróficas, sem efeitos adversos. Enxertos de pele são essenciais para queimaduras graves, restaurando a integridade cutânea e funcional. Enxertos autógenos são preferidos por menor risco de rejeição e infecção, enquanto enxertos alógenos são usados temporariamente em queimaduras extensas. O manejo de queimaduras envolve uma abordagem multidisciplinar, com cuidados intensivos, suporte nutricional, terapia física e psicológica, e intervenções cirúrgicas, como enxertos de pele.
PANORAMA CLÍNICO-EPIDEMIOLÓGICO DE CASOS CONFIRMADOS DE MENINGITE NA POPULAÇÃO PEDIÁTRICA BRASILEIRA : ANÁLISE DE 10 ANOS
Authors: CAVALCANTE CARVALHO CLARA VITÓRIA , Brito Martins Paulo Victor , de Castro Beserra-Dias Iane Camile , Dalmaso Pieroni Lucas , Carvalho Abreu Ana Carolina , Barreto da Silva Renata , Amorim Araújo Jaine , Ribeiro dos Santos Andreia , Da Silva Cavalcante Erika , Duarte Cantanhede João Arthur , Duarte Cantanhede Ana Luísa , Dutra de Almeida Iasmin , Nascimento Castro Carla Cilene , Gomes de Melo Wellington Rodrigo , Monteiro Sodré Andressa , Oliveira Rodrigues Luiza , Pinheiro Prates Malik
Published: July 2024

A meningite é um  problema de saúde pública que pode acometer qualquer faixa etária, porém tem-se um destaque para crianças, ela possui como agentes etiológicos bactérias, vírus, parasitas e, raramente, causas não infecciosas. Os quadros clínicos apresentam-se, em sua maioria, através de náuseas, vômitos, diarreia, taquicardia, hipotensão e petéquias na pele. Dessa maneira, o estudo tem por objetivo avaliar o perfil clínico e epidemiológico de casos de meningite, no Brasil, em pacientes pediátricos, em 10 anos.  Trata-se de um estudo descritivo,retrospectivo e quantitativo realizado através de dados secundários obtidos pelo DATASUS e Sistema de Morbidade Hospitalar (SINAN). As variáveis analisadas foram: ano de notificação, capital de residência, faixa etária, nível de escolaridade, cor/raça, sexo, período gestacional, tipo de dengue,  critério de confirmação, evolução e hospitalização. Com relação à faixa etária, considerou indivíduos menores de 1 ano a 14 anos.  A faixa etária mais prevalente é a de crianças pré escolares entre 1 a 4 anos de idade (34,02%), do sexo masculino (59%) , brancas (48,89%), residentes do Estado de São Paulo (40%), apresentando confirmação de diagnóstico majoritamente por exame quimiocitológico do líquor. Ademais, nota-se que a etiologia mais prevalente é a viral. Desse modo,  a realização de investigações adicionais sobre a prevalência da meningite na população brasileira é crucial para o desenvolvimento de políticas públicas destinadas à prevenção e controle da doença.
Craniofaringioma e manejo do pan-hipopituitarismo
Authors: Sousa da Silva Romulo , Da Rocha Araújo Tiago , Vinícius Almeida Santos Marcos , Balica de Oliveira Davi , Soares Pires Wesley , Crispim Vergine de Freitas Davi , Simões Azevedo Lavynne , Álvares Bitencourt Caio , Quirino de Oliveira Mariana , Hallich França da Silva Vanessa , Alves Vitor Mirelly , Carolina Bezerra Góes Ana
Published: July 2024

Craniofaringiomas são tumores benignos raros derivados de remanescentes da bolsa de Rathke, localizados no espaço suprasselar. Representam de 1 a 3% de todos os tumores cerebrais, com duas faixas etárias de incidência predominantes: crianças (5-15 anos) e adultos (5ª década de vida). Os subtipos principais são papilar e adamantinomatoso, sendo este último mais comum. Eles crescem lentamente e podem invadir localmente estruturas adjacentes, causando morbidade significativa devido ao efeito de massa e complicações endócrinas como hipopituitarismo e obesidade hipotalâmica. O diagnóstico baseia-se principalmente em exame de imagem, geralmente ressonância magnética, que revela uma massa suprasselar capaz de comprimir o quiasma óptico. Os sintomas incluem distúrbios visuais, dores de cabeça e déficits hormonais, especialmente em crianças. O caso em questão envolveu um homem de 30 anos com hemianopsia progressiva e cefaleia. Após ressonância magnética diagnosticar uma lesão expansiva de 20 x 10 x 10 mm, ele foi submetido à abordagem transesfenoidal para biópsia e ressecção subtotal, seguida por radioterapia adjuvante. Apesar de desenvolver panhipopituitarismo, tratado com hormônios e corticosteroides, o paciente está assintomático após 5 anos, com controle de ressonância mostrando uma lesão remanescente de 5 x 4 x 6 mm. Em suma, o craniofaringioma, apesar de benigno, apresenta desafios significativos devido à sua complexa localização e potenciais complicações. O manejo terapêutico envolve decisões entre diferentes abordagens cirúrgicas, radioterápicas e medicamentosas com atenção especial para preservar a qualidade de vida, especialmente em pacientes jovens. O diagnóstico precoce e a abordagem multidisciplinar são fundamentais para otimizar os resultados e garantir um acompanhamento adequado.
Análise epidemiológica da morbidade hospitalar por fratura de crânio e dos ossos da face em idosos brasileiros em 5 anos
Authors: Guimarães Figueiredo Cavalcante Maria Clara , Ferreira Pessotti Martins Laíza , Duran de Azevedo Ian , Dias Vieira Neto Salvador , Barreto Cortez Larissa , Vasconcelos Bittencourt Boaventura Raíssa , De Castro Nagata Maiana Larissa , Cardoso de Oliveira Débora , Fois Cotta Ana Carolina , Ribeiro Alencar do Amaral Lorena
Published: July 2024

O trauma, devido ao aumento da violência e acidentes, é um problema emergente de saúde pública, com traumas na cabeça e face sendo comuns. O Traumatismo Crânio-Encefálico (TCE) causa lesões diversas e é uma epidemia silenciosa, especialmente em países subdesenvolvidos. Globalmente, o TCE é uma das principais causas de morte entre jovens adultos, com alta incidência nos EUA. Este trabalho é um estudo ecológico, quantitativo e retrospectivo, baseado em dados do SIH/SUS e DATASUS. As variáveis analisadas incluem região, tipo de atendimento, sexo e cor/raça. Das internações por fratura de crânio e face em idosos, 78,72% foram por urgência, 14,17% eletivas e 7,09% por outros acidentes. A maioria dos pacientes (71,30%) era masculina. Em termos de cor/raça, 41,84% eram brancos, 38,56% pardos, e 4,04% pretos.
Perspectivas para o tratamento da neuromielite óptica: uma revisão de literatura
Authors: Nascimento João Pedro Alves , Ranucci Murillo Miranda , Borges Karina Gabriella da Costa , Soares Yzandro Rocha Ferreira , Santos Paulo Thassilys Antunes , Magalhães Isolda Cardoso de Castro , Mendes Marlizon Gonçalves , Alves Alana Fernandes , Santos Gilvan Bomfim dos , Filho Ricardo Penalva da Silva , Araújo Letícia Amorim , Sobral Isadora Mendes , Gomes Flávia Luísa Novais , Ramalho Eudes Alexandre de Medeiros
Published: July 2024

Introdução: A neuromielite óptica (NMO) é uma doença inflamatória autoimune desmielinizante que acomete o sistema nervoso central afetando predominantemente os nervos ópticos e a medula espinhal. As manifestações clínicas normalmente acontecem em um caráter surto-remissão sendo progressivamente incapacitantes e com alto risco de mortalidade. (Luo et al., 2022). Visando prevenir essas recidivas e incapacidades, novos tratamentos  sequenciais são de grande interesse para a prática médica. Objetivo: comparar os tratamentos sequenciais atuais para a neuromielite óptica. Metodologia: trata-se de uma revisão de literatura sobre os tratamentos sequenciais atuais para NMO, cujos dados foram obtidos através de uma busca na Biblioteca Virtual de Saúde (BVS) com a estratégia de pesquisa: “neuromyelitis optica” AND “therapy”. Foram selecionados 3 artigos que atenderam ao critério de revisão sistemática com meta-análise dos últimos 5 anos com tema principal de tratamento da neuromielite óptica. Resultados e discussão: a terapia sequencial se baseia em corticosteroides orais e, principalmente, na imunossupressão de células alteradas do sistema imune, especialmente na depleção dos linfócitos do tipo B. Nesse sentido, vários fármacos são empregados como eculizumabe (ECZ), azatioprina (AZA), e rituximab (RTX). O primeiro se mostrou eficaz na prevenção de recaídas em 98,9% dos pacientes em 2 anos, enquanto o RTX e a AZA se destacam por sua segurança (Luo et al., 2022). Ainda, o RTX se mostra mais eficaz que a AZA na redução anual das recidivas (Diferença Média Ponderada de 1,45 após o tratamento) e da progressão medida pela Escala Expandida do Estado de Incapacidade (EDSS) (Dong; Meng; Xiao, 2022), sendo, portanto, um destaque entre as formas de tratamento. Ademais, o transplante autólogo de células-tronco hematopoiéticas após condicionamento local com imunossupressores tem se mostrado favorável para casos graves, com a redução de 0,81 pontos da EDSS (Nabizadeh et al., 2022). Conclusão: o rituximab tem se mostrado como a nova terapia sequencial mais promissora, devido a sua segurança e eficácia em comparação às outras imunossupressoras
PERFIL DA MORTALIDADE INFANTIL POR CAUSAS EVITÁVEIS SEGUNDO REGIÃO DO BRASIL
Authors: Oliveira Renata Angélica Ferreira de , Fernandes Carlos Eduardo Real , Silva Fernanda Moreira da , Feitosa Gabriela Maria Nascimento , Bauman Claudiana Donato
Published: July 2024

Este artigo tem por objetivo apresentar os principais dados epidemiológicos da mortalidade infantil de zero a quatro anos de idade por causas evitáveis e região do Brasil, nos anos de 2017 a 2022. Trata-se de um estudo epidemiológico de caráter descritivo e ecológico com abordagem quantitativa. O estudo foi conduzido com base em dados obtidos do Departamento de Informática do Sistema Único de Saúde, explicitados no Tabenet. Os dados secundários referentes, foram acessados durante os meses de janeiro e abril de 2024 considerando as cincos regiões do Brasil. Os resultados mostraram maior taxa de mortalidade nas regiões sudeste e nordeste em todos os seis anos analisados. Dentre as causas evitáveis, a atenção à mulher na gestação foi a mais prevalente no ano de 2022. Crianças do sexo masculino e raça branca apresentaram maior taxa de mortalidade nos seis primeiros dias de vida. Conclui-se, que embora os índices apontem redução da mortalidade infantil na comparação aos anos anteriores, é claramente visível que trata-se de óbitos com causas passíveis de serem evitadas. O reforço de políticas existentes no Brasil, assim como a implementação estratégica de ações de acordo com as necessidades de cada região, se apresentam como importantes ferramentas nesse contexto.
Analisis Maraknya Eksploitasi Buruh Anak pasca Liberalisasi Perdagangan di Tiongkok
Authors: Sukmatika Anak Agung Yumas
Published: July 2024

Penelitian ini menggunakan teori Marxisme guna menyelidiki alasan di balik meningkatnya jumlah buruh anak di Tiongkok. Sejak liberalisasi perdagangan dan reformasi ekonomi dimulai pada 1978, Tiongkok telah mengalami pertumbuhan ekonomi yang luar biasa. Saat ini ekonomi Tiongkok berada di posisi kedua terbesar di dunia setelah Amerika Serikat (AS). Namun jumlah buruh anak telah meningkat karena tajamnya perbedaan ekonomi terutama antara kota dan desa serta kebutuhan akan tenaga kerja murah di industri. Penelitian ini menggunakan metode kualitatif dengan pendekatan studi pustaka untuk menganalisis data non-numerik dan deskriptif dari berbagai sumber literatur, termasuk buku, artikel jurnal, dan laporan penelitian. Studi ini menunjukkan bahwa liberalisasi perdagangan telah memperburuk eksploitasi tenaga kerja di Tiongkok. Regulasi yang melarang pekerja anak sering diabaikan oleh pemerintah setempat termasuk perusahaan untuk meningkatkan keuntungan. Selain itu terdapat asumsi yang dinormalisasi bahwa anak-anak adalah sumber pendapatan daripada individu yang membutuhkan perawatan dan pendidikan. Banyak orang tua Tiongkok mempekerjakan anak-anak sebagai penopang ekonomi keluarga daripada memberikan dukungan pendidikan yang cukup. Hasil penelitian ini menunjukkan bahwa eksploitasi buruh anak masih ada dan bahkan meningkat meskipun pertumbuhan ekonomi seharusnya meningkatkan kesejahteraan masyarakat. Pada akhirnya asumsi-asumsi dasar Marxisme yakni historical materialism, economic determinism, dan false consciousness berkontribusi signifikan dalam menjawab alasan di balik peningkatan jumlah buruh anak di Tiongkok.
Edukasi Berbasis Lingkungan sebagai upaya Meningkatkan Kepedulian Masyarakat di Bantaran Kali Acai Abepura
Authors: Sapioper Hiskia CM. , Modouw James , Ramandei Lazarus
Published: July 2024

Kegiatan Pengabdian Kepada Masyarakat tentang edukasi berbasis lingkungan, sebagai upaya meningkatkan kepedulian masayarakat terhadap kualitas lingkungan hidup, tetapi juga merupakan salah satu bentuk kepedulian tim pengabdian dari Universitas Cenderawasih terhadap permasalahan lingkungan yang semakin kurang terkendali di sepanjang Kali Acai. Melalui edukasi berbasis lingkungan mampu membentuk jiwa-jiwa yang mempunyai kepedulian lingkungan yang tinggi. Dimulai dari kalangan masyarakat bawah dan menengah, diharapkan akan menjadi agen perubahan. Melalui kegiatan sosialisasi serta menggunkana media kampanye lingkungan lewat lagu dan seruan akan keselamatan lingkungan diharapkan dapat menginspirasi kalangan masyarakat sehingga tercapai kondisi masyarakat sebagai agen perubahan untuk lingkungan di masa mendatang. Kegiatan Pengabdian Masyarakat ini bertujuan untuk membentuk pola pikir dan kepedulian masyarakat dalam menggalakkan gerakan peduli lingkungan agar tercipta keadaan bersih, nyaman, dan sehat yang dimulai dari melakukan edukasi pentingnya menjaga kebersihan lingkungan, pengenalan dan penggolongan jenis sampah yang ada di sekitar, cara pemanfaatan sampah, penanaman tanaman di sekitar lingkungan sendiri, dan kampanye lingkungan melalui lagu serta seruan akan keselamatan lingkungan dan bumi. Kebersihan lingkungan harus dari lingkungan keluarga sehingga membentuk pola pikir yang jauh ke depan dan akan menjadi agen perubahan di lingkungan mereka melalui program edukasi pola hidup sehat.
The Role of the Nawasena Kemala as an Added Economic Value for the Daleman Kidul Village
Authors: Fitriana Yenny Reiza , Hapsari Salsabila Nur , Hartono Budi , Robbani Hamzah
Published: July 2024

This service is an output of activities from the Ministry of Education and Culture, Research and Technology's Belmawa grant funding to PPK Ormawa HMJM Tidar University. This service activity aims to improve the quality of organic and non-organic waste processing in Daleman Kidul Village, Pakis District, Magelang Regency. The method for implementing PPK Ormawa HMJM UNTIDAR service activities is in the form of training and counseling, as well as the establishment of institutions at the village level to create sustainability of the waste processing program. The objects of this activity are residents' agricultural waste, residents' kitchen waste, and plastic waste which can still be used as handicrafts, while residual waste is collected for collective processing at the Magelang Regency Environmental Service. Internal partners involved in this activity include the Village Head, Village Secretary, Kadus, Babinsa, Bhabinkamtibnas, Tomas, religious figures. PKK mothers and Karangtaruna. Meanwhile, external partners in this activity include academics across universities in Magelang Regency, Bappeda Litbangda Magelang Regency,MySmash app, and various Department elements within the Magelang Regency Government. The tools and materials used are a set of tools for cultivating maggots, a shelter for making compost fertilizer, and supporting tools for making handicrafts. The result of this service activity is the organized handling of both organic and non-organic waste banks, as well as increasing public awareness in managing waste into economically valuable products.
Narrativas de um professor de matemática do Curso Normal do IEEOB: descortinando memórias
Authors: Coradini Carla , Mariani Rita de Cássia Pistóia
Published: July 2024

O objetivo deste artigo é apresentar memórias da formação do Prof. Edenel, trajetória profissional e o ensino de matemática no Curso Normal do Instituto Estadual de Educação Olavo Bilac (IEEOB) no período de 1987 a 2008. A demarcação temporal foi estabelecida em função da constatação que o professor foi quem mais tempo ministrou aulas de Matemática no Curso. A metodologia da história oral foi suporte teórico-metodológico para a realização da entrevista e diálogo com as memórias. Como resultados evidenciou-se que a trajetória escolar contribuiu para a escolha da profissão professor de Matemática. A formação acadêmica foi sólida no que tange conhecimentos matemáticos, porém escassa em saberes pedagógicos. O ensino de matemática destacou conteúdos como medidas e abordagem reflexiva e crítica. Concluiu-se que a formação e trajetória profissional do entrevistado apresenta congruência e riqueza de experiências que se refletiu na atuação docente e no modo de e como ensinar Matemática.
Numerical investigation of the impact of various parameters on blowing accuracy in the XRT intelligent ore sorting machine blowing process
Authors: FAN Jiayu , RAO Yuhuan , LIU Sidong , YU Xinyang
Published: July 2024

XRT separation equipment is attracting much attention as the mining industry increasingly uses pre-sorting technology. Its sorting accuracy is affected by differences in ore shape and particle size during operation. This paper, in which numerical simulations are conducted to investigate the resistance of ores under various situations, including varying blowing distances, cross-sections, and practical sizes, Additionally, this paper conducts validation tests. The test results indicate that within the 0.1-0.25 m section from the nozzle exit, there is a rapid decrease in velocity, accompanied by a significant change in ore resistance. Beyond the 0.25 m mark, the velocity reduction slows down, while the ore resistance becomes smaller. There exists a notable disparity in the resistance of ores with varying cross-sectional geometries. The size of the jet velocity surface caused by blowing distance significantly influences the resistance of ore with varying particle sizes. Furthermore, the resistance of the ore remains constant subsequent to the impact surface of the ore surpassing the surface of the jet velocity. Consequently, appropriately modifying the blowing distance, inlet pressure, and jet speed in accordance with the cross-sectional area and particle size of the majority of the ores stream can enhance the precision of the sorting process.
A hydrometallurgical process for the recovery of copper metal and nickel hydroxide from the aqua regia leaching solutions of printed circuit boards
Authors: Nguyen Thi Nhan Hau , Wen Jiangxian , Lee Man Seung
Published: July 2024

Leaching solutions of printed circuit boards (PCBs) contain noble and base metal ions. The precious metal ions present in the leaching solutions of PCBs could be separated by cementation with copper metal. After recovery of precious metal ions by cementation, the filtrate contains Cu(II) together with base metal ions like Al(III), Fe(III), Fe(II), Ni(II), Sn(II), and Zn(II). In this work, separation experiments were conducted to recover Cu(II) and Ni(II) from the filtrate. First, copper ions were completely separated from the filtrate by chemical reduction with hydrazine at the following conditions: a molar ratio of 8 for hydrazine to Cu(II), 20°C, 500 rpm, and 20 mins. By adding sodium oxalate to the solution after separation of Cu(II), most of the Ni(II) and 38% of the Zn(II) were co-precipitated at 20°C, 60 mins, 500 rpm, and a molar ratio of 20 for sodium oxalate to nickel. After dissolving the co-precipitates of Ni(II) and Zn(II) oxalates in a 0.5 M HCl solution, the Zn(II) was completely removed from the solution by a five-stage cross-current extraction with 2.5 M Cyanex 272. Nickel hydroxides were then recovered from the raffinate by precipitation with NaOH. The purity of the copper metal and nickel hydroxides was higher than 99%. A process was proposed to recover Au(III), Pd(II), Cu(II), and Ni(II) from the leaching solutions of PCBs.
Exploring the impact of thiol collectors system on copper sulfide flotation through machine learning-driven modeling
Authors: Guner Mustafa , Akyildiz Ozge , Basarir Hakan , Kowalczuk Pshem
Published: July 2024

Collector selection is a critical step in flotation, as it has a direct impact on product quality, flotation recovery, and selectivity. Collectors can consist of different components, and their effectiveness can vary depending on the type of ore being processed. The general practice in both literature and in industry is to use a mixture of collectors rather than a single collector. However, the use of a collector mixture introduces several complex issues. It is challenging to determine the specific effects of each collector on different minerals, as well as to understand the synergistic effects of mixed collectors in flotation. This study presents a novel investigation focusing on the impact of blends of NAX, AEROPHINE® 3422, and AERO® MX 5149, in varying dosages and combinations, on the flotation performance of Kupferschiefer copper ore. Kinetics flotation tests were conducted using a mechanical flotation cell with various combinations and dosages of listed collectors. For this investigation, different predictive models such as machine-learning (ML) and conventional regression analyses were developed. For model construction, a database including the results of comprehensive experimental results was constructed. The best performing model was selected considering statistical performance indicators and their performance on unseen data. A sensitivity analysis was conducted on the model to justify contributions of collectors on the copper recovery and grade. The results showed that the ML-based models provide compatible results with the expert opinions and have higher statistical performance than conventional modelling tools. According to the experimental results and models’ findings, it has shown that AEROPHINE® 3422 (a blend of isopropyl ethyl thionocarbamate and dithiophosphinate) was the most influential collector for the copper recovery. In addition, two ternary graphs were generated from the modeled data to formulate mixtures for different grades and recovery priorities.
Effect of surfactant and PAM on the settlement of kaolinite particles and its mechanism analysis
Authors: Zhang Jinxia , Zhang Mengfei , Niu Fusheng , Wang Ziye , Cheng Zehong , Wang Qiuyue
Published: July 2024

High concentrations of fine-grained clay minerals in tailings water are highly detrimental to environmental protection and water recycling. Using kaolinite as the study subject, this research investigates the effects of various cationic surfactants (DDA, DTAB, TTAB, CTAB) and flocculants (APAM, NPAM, CPAM) on the sedimentation of kaolinite particles. The study explores the impact of single agents, combined agents, and the sequence of their addition on kaolinite particle sedimentation. The results indicate that when using individual agents at low concentrations, CTAB outperforms TTAB, DTAB, and DDA, while APAM is more effective than NPAM and CPAM. The optimal performance is achieved with a CTAB concentration of 2×10-4 mol/L and an APAM dosage of 20 mg/L. When combining agents, the best results are observed when CTAB is added before APAM. By fixing the APAM dosage at 20 mg/L and varying the CTAB concentration, the highest sedimentation rate and lowest turbidity are obtained at a CTAB concentration of 1.5×10-4 mol/L. Mechanistic insights were obtained through aggregate imaging, area measurement, zeta potential testing, and contact angle testing. Cationic surfactants alter the surface properties of particles, reducing surface electronegativity and increasing hydrophobicity, which diminishes inter-particle repulsion and promotes aggregation, thereby reducing turbidity. Flocculants form larger flocs through adsorption and bridging, accelerating the sedimentation process. When flocculants and cationic surfactants are used together, the resulting flocs are more stable and larger, with an average floc area reaching 5017.6079 µm2, indicating a significant reduction in fine particles within the solution.
Evaluation of the pharmacognostic parameters, qualitative phytochemical profile and investigation of the toxicity of Sacoglottis ceratocarpa Ducke containing Bergenin, a gallic acid derivative
Authors: de Oliveira Gustavo Rezende Bellei ,   Federal University of Parana, Rocha Fabiola Dutra , Nunomura Rita de Cassia Saraiva , Roberto Joao Paulo , Merino Francis Jose Zortea , de Oliveira Vinicius Bednarrczuk , Rech Katlin Suellen , Alves Emellie Cristine , Furusho Aletheia dos Santos , Montrucchio Deise Orehs , Dias Josiane de Fatima Gaspari , Valdameri Glaucio , Zanzarini Isadora da Silva , Miguel Obdulio Gomes , Miguel Marilis Dallarmi ,   Federal University of Juiz de Fora,   Federal University of Amazonas,   Federal University of Parana,   Federal University of Parana,   Federal University of Parana,   Federal University of Parana,   Federal University of Parana,   Federal University of Parana,   Federal University of Parana,   Federal University of Parana,   Federal University of Parana,   Federal University of Parana,   Federal University of Parana,   Federal University of Parana
Published: July 2024

Trunk barks of Sacoglottis ceratocarpaDucke (ScTB) are used in Amazonian folk medicine against hyperglycemia and dyslipidemia, although scientific information on efficacy and quality control is lacking. Thus, pharmacognostic parameters, qualitative phytochemical profile, antioxidant properties (DPPH, TEAC and FRAP), toxicity and cytotoxicity were evaluated. The purity tests in the quality control performed for the vegetable raw material showed compliance with the specifications in official compendiums. Tannins, catechins, terpenes and steroids were characterized. Bergenin, a gallic acid derivative, was isolated and identified. The ScTB was rich in total phenolic (0.420-0.562 g/g) and flavonoid (11.37-24.31 mg/g) content, and considerable antioxidant potential. ScTB did not demonstrate cytotoxicity for human erythrocytes and renal fibroblasts, nortoxicity for brine shrimp. The results demonstrated the importance of the pharmacognostic study for the immediate knowledge of the quality and qualitative chemical profile of the trunk barks, contributing to the safe and effective use of the species.
Gastroesophageal reflux following peroral endoscopic myotomy for achalasia: Bumps in the road to success
Authors: Itskoviz David , Malnick Stephen David Howard
Published: July 2024

Achalasia can significantly impair the quality of life. The clinical presentation typically includes dysphagia to both solids and liquids, chest pain, and regurgitation. Diagnosis can be delayed in patients with atypical presentations, and they might receive a wrong diagnosis, such as gastroesophageal reflux disease (GERD), owing to overlapping symptoms of both disorders. Although the cause of achalasia is poorly understood, its impact on the motility of the esophagus and gastroesophageal junction is well established. Several treatment modalities have been utilized, with the most common being surgical Heller myotomy with concomitant fundoplication and pneumatic balloon dilatation. Recently, peroral endoscopic myotomy (POEM) has gained popularity as an effective treatment for achalasia, despite a relatively high incidence of GERD occurring after treatment compared to other modalities. The magnitude of post-POEM GERD depends on its definition and is influenced by patient and procedure-related factors. The long-term sequelae of post-POEM GERD are yet to be determined, but it appears to have a benign course and is usually manageable with clinically available modalities. Identifying risk factors for post-POEM GERD and modifying the POEM procedure in selected patients may improve the overall success of this technique.
Prevalence of Helicobacter pylori infection among patients with esophageal carcinoma
Authors: López-Gómez Miriam , Morales Maria , Fuerte Rebeca , Muñoz Marta , Delgado-López Pedro-David , Gómez-Cerezo Jorge Francisco , Casado Enrique
Published: July 2024

BACKGROUND

Helicobacter pylori (H. pylori ) is a widespread microorganism related to gastric adenocarcinoma (AC). In contrast, it has been reported that an inverse association exists between H. pylori infection and esophageal carcinoma. The mechanisms underlying this supposedly protective effect remain controversial.

AIM

To determine the prevalence of H. pylori infection in esophageal carcinoma patients, we performed a retrospective observational study of esophageal tumors diagnosed in our hospital.

METHODS

We retrospectively reviewed the prevalence of H. pylori infection in a cohort of patients diagnosed with esophageal carcinoma. Concomitant or previous proton pump inhibitor (PPI) usage was also recorded.

RESULTS

A total of 89 patients with esophageal carcinoma (69 males, 77.5%), with a mean age of 66 years (range, 26-93 years) were included. AC was the most frequent pathological variant (n = 47, 52.8%), followed by squamous cell carcinoma (n = 37, 41.6%). Fourteen ACs (29.8%) originated in the gastroesophageal junction and 33 (70.2%) in the esophageal body. Overall, 54 patients (60.7%) presented at stages III and IV. Previous H. pylori infection occurred only in 4 patients (4.5%), 3 with AC (6.3% of all ACs) and 1 with squamous cell carcinoma (2.7% of all squamous cell tumors). All patients with previous H. pylori infection had stage III-IV. Only one patient had received prior H. pylori eradication therapy, whereas 86 (96.6%) had received previous or concomitant PPI treatment.

CONCLUSION

In our cohort of patients, and after histologic evaluation of paraffin-embedded primary tumors, we found a very low prevalence of previous H. pylori infection. We also reviewed the medical history of the patients, concluding that the majority had received or were on PPI treatment. The minimal prevalence of H. pylori infection found in this cohort of patients with esophageal carcinoma suggests a protective role.
Leech Poecilobdella manillensis protein extract ameliorated hyperuricemia by restoring gut microbiota dysregulation and affecting serum metabolites
Authors: Liu Xia , Liang Xing-Qiu , Lu Tian-Cai , Feng Zhe , Zhang Min , Liao Nan-Qing , Zhang Feng-Lian , Wang Bo , Wang Li-Sheng
Published: July 2024

BACKGROUND

Hyperuricemia (HUA) is a public health concern that needs to be solved urgently. The lyophilized powder of Poecilobdella manillensis has been shown to significantly alleviate HUA; however, its underlying metabolic regulation remains unclear.

AIM

To explore the underlying mechanisms of Poecilobdella manillensis in HUA based on modulation of the gut microbiota and host metabolism.

METHODS

A mouse model of rapid HUA was established using a high-purine diet and potassium oxonate injections. The mice received oral drugs or saline. Additionally, 16S rRNA sequencing and ultra-high performance liquid chromatography with quadrupole time-of-flight mass spectrometry-based untargeted metabolomics were performed to identify changes in the microbiome and host metabolome, respectively. The levels of uric acid transporters and epithelial tight junction proteins in the renal and intestinal tissues were analyzed using an enzyme-linked immunosorbent assay.

RESULTS

The protein extract of Poecilobdella manillensis lyophilized powder (49 mg/kg) showed an enhanced anti-trioxypurine ability than that of allopurinol (5 mg/kg) (P < 0.05). A total of nine bacterial genera were identified to be closely related to the anti-trioxypurine activity of Poecilobdella manillensis powder, which included the genera of Prevotella , Delftia , Dialister , Akkermansia , Lactococcus , Escherichia_Shigella , Enterococcus , and Bacteroides . Furthermore, 22 metabolites in the serum were found to be closely related to the anti-trioxypurine activity of Poecilobdella manillensis powder, which correlated to the Kyoto Encyclopedia of Genes and Genomes pathways of cysteine and methionine metabolism, sphingolipid metabolism, galactose metabolism, and phenylalanine, tyrosine, and tryptophan biosynthesis. Correlation analysis found that changes in the gut microbiota were significantly related to these metabolites.

CONCLUSION

The proteins in Poecilobdella manillensis powder were effective for HUA. Mechanistically, they are associated with improvements in gut microbiota dysbiosis and the regulation of sphingolipid and galactose metabolism.
Defining failure of endoluminal biliary drainage in the era of endoscopic ultrasound and lumen apposing metal stents
Authors: Ali Faisal S , Guha Sushovan
Published: July 2024

The role of endoscopy in pathologies of the bile duct and gallbladder has seen notable advancements over the past two decades. With advancements in stent technology, such as the development of lumen-apposing metal stents, and adoption of endoscopic ultrasound and electrosurgical principles in therapeutic endoscopy, what was once considered endoscopic failure has transformed into failure of an approach that could be salvaged by a second- or third-line endoscopic strategy. Incorporation of these advancements in routine patient care will require formal training and multidisciplinary acceptance of established techniques and collaboration for advancement of experimental techniques to generate robust evidence that can be utilized to serve patients to the best of our ability.
Evaluating the role of large language models in inflammatory bowel disease patient information
Authors: Gong Eun Jeong , Bang Chang Seok
Published: July 2024

This letter evaluates the article by Gravina et al on ChatGPT’s potential in providing medical information for inflammatory bowel disease patients. While promising, it highlights the need for advanced techniques like reasoning + action and retrieval-augmented generation to improve accuracy and reliability. Emphasizing that simple question and answer testing is insufficient, it calls for more nuanced evaluation methods to truly gauge large language models’ capabilities in clinical applications.
Tinjauan Atas Prosedur Pembelian Dan Penjualan Pada PT Jaya Makmur Pajajaran
Authors: Agustiansyah Keukeu , Efrianti Desi , Rosita Siti Ita
Published: July 2024

Sistem informasi akuntansi menjadi salah satu hal yang sangat penting dalam mendukung kegiatan perusahaan. Dengan sistem yang dapat menunjang seluruh kegiatan, maka akan dengan mudah terlaksananya prosedur-prosedur usaha seperti prosedur pembelian dan penjualan pada perusahaan. PT Jaya Makmur Pajajaran merupakan perusahaan dagang yang bergerak dibidang penjualan peralatan rumah tangga. Penulis melakukan observasi dengan mengumpulkan data, dokumentasi, dan studi pustaka sesuai dengan bidang-bidang yang berkaitan. Tujuan dari peninjauan ini adalah untuk mengetahui bagaimana prosedur pembelian dan penjualan yang diterapkan oleh PT Jaya Makmur Pajajaran. Hasil dari peninjauan ini adalah PT Jaya Makmur Pajajaran telah menerapkan prosedur pembelian dan prosedur penjualan sesuai dengan ketentuan dan kebijakan perusahaan, namun masih terdapat kendala-kendala yang terjadi seperti kurang efektif dan efisiennya dalam hal sumber daya manusia. Meskipun begitu, PT Jaya Makmur Pajajaran telah memberikan upaya dan kebijakan agar kendala dapat teratasi dengan baik.
Keywords: prosedur pembelian, prosedur penjualan, sistem informasi akuntansi.
Tinjauan atas lini produk pada PT Batara Indah Bantex
Authors: Fakhri Muhammad faiz , Purnama Denta
Published: July 2024

Pembahasan ini berjudul Tinjauan Atas Lini Produk Pada PT. Batara Indah. Tujuan dari pembahasan ini yaitu untuk mengetahui penerapan lini produk yang dilakukan oleh PT. Batara Indah, dan bagaimanakah teori dan praktek penerapan lini produk pada PT. Batara Indah.
Berdasarkan hasil dari peninjauan yang dilakukan oleh penyusun pada PT. Batara Indah yang menunjukkan bahwa penerapan lini produk pada PT. Batara Indah menggunakan indikator kebutuhan masyarakat saat ini yang semakin meningkat. Dengan menggunakan indikator tersebut, maka dapat diketahui seberapa penting  kebutuhan konsumen pada suatu produk.
Tujuan pembahasan yang dilakukan oleh penulis yaitu : 1) untuk mengetahui penerapan lini produk pada PT. Batara Indah, 2) untuk mengetahui kendala dalam penerapan lini produk pada PT. Batara Indah, 3) untuk mengetahui upaya menangani kendala dalam penerapan lini produk pada PT. Batara Indah.
Adapun keuntungan jika perusahaan menerapkan lini produk yaitu konsumen dari PT. Batara Indah dapat memilih sesuai harga, warna, kualitas dari produk tersebut, sehingga produk tersebut tidak dikhususkan pada segmen atas saja tapi harga tersebut masuk dalam semua segmen dari yang terendah sampai segmen tertinggi.
 
 
Kata kunci : PT. Batara Indah, lini produk