bluuebunny/crossref_metadata_2025 huggingface dataset:
Detection of Cpy-2, Fks and Erg 11 Genes in Fungal Isolates from Sars Cov-2 Individual in Ibadan, Oyo State, Nigeria
Authors: F Bamigbola
Published: March 2023

A considerable number of fungal strains have developed resistant to various available antifungal agents due to CPY, FKS and or ERG11 genes complicating coinfection cases of SAR COV-2 virus. Therefore, this study sought to isolate, identify azole and polyene resistant genes in fungal pathogens isolated from confirmed SARS-CoV-2 individual in Oyo State, Nigeria. Nasopharyngeal samples were collected from symptomatic and asymptomatic SARS-CoV-2 infected adult from September, 2020 to April, 2021. Samples were cultured on Sabouraud Dextrose Agar at room and at 37 oC temperature for 7days. Identification of the fungal isolates were performed using MALDITOF MS VITEK. Antifungal Susceptibility Testing (AFST) were performed using Kirby bauer disc diffusion method. The resistant genes in fugal isolates were determined by Polymerase Chain Reaction with specific primers and resistant genes were amplified using agarose gel electrophoresis. Out of 63(15.8%) fungal isolates recorded from 400 samples collected, Asipergillus flavus 11(17.5%), Aspergillus niger 9(14.3%), Candida albicans 7(11.1%), Candida guillermondii 2(3.2%), Candida parapsilosis 2(3.2%), Candida famata 2(3.2%), Candida tropicalis 5(7.9%) and Lodderomyces elongisporus 25(39%) having highest frequency were recorded respectively. Nystatin (84.1%) had highest susceptibility testing and Ketoconazole (39.7%) had the least phenotypically. 10 (52.6%) isolates possessed CPY gene, 8(42.1%) isolates carried FKS gene, 9(47.4%) isolates had ERG11 gene molecularly.
Motor Screenings for Primary School Children-A Review
Authors: Dincher Andrea
Published: March 2023

Importance: Motor deficits must be detected as early as possible to avoid negative consequences for the affected child. Within the framework of a sequential diagnostic strategy, screening should be used first in order to keep the testing effort for all children as low as possible. Objective: The present study investigates the question of whether such motor screening procedures exist for primary school children and meet all necessary psychometric properties. Evidence review: The literature search was conducted by January and February 2023. The electronic sources Dialnet, ERIC, PSYNDEX, PubMed, and SpoLit were systematically searched (publications in English, German, French and Spanish). Results: A total of 1092 publications were found based on the selected keywords. After removing duplicates and screening the articles for eligibility, 433 publications were included in further analysis. In this process, 11 putative screenings were found. However, only one of them meets all the required psychometric properties in a high degree. Conclusions: Actually, only MobiScreen 6-8 fulfills all criteria and can be recommended for the first step in a sequential diagnostic strategy. An appropriate screening for children between eight and ten years is lacking.
Translational Pharmacogenomics Augmenting Pharmacotherapy
Authors: Uppaluri Kalyan Ram
Published: March 2023

Pharmacogenomics (PGx), the intertwined knowledge of pharmacology and genomics, is well known. Taking PGx in pace with modern sequencing technological advancements is essential for effective clinical utilization, implementation, and personalized treatment care. Molecular profiling is a technique used to analyze the genetic and molecular makeup of an individual's cancer or other diseases. Decisions on a patient's course of treatment, including the choice of an appropriate pharmacotherapy, can be made using this information. For example, molecular analysis can pinpoint genetic changes that increase a patient's propensity to respond to a particular treatment. It can also reveal potential resistance mechanisms, which helps choose effective treatments for patients. In addition, molecular profiling can help to identify possible side effects that a patient may experience when taking certain medications. Overall, molecular profiling can be a valuable tool in helping to optimize pharmacotherapy for an individual patient. This review highlights the history of PGx, the role of pharmacogenes, PGx guidelines, the interrelation between PGx and personalized medicine, PGx technologies, challenges, and solutions in the implementation of PGx, international and national execution of PGx, and PGx in geriatric patient care, pediatric patient care, maternal, fetal medicine, general medicine, and oncology with a focus on the international and national scenarios. This review aims to better elucidate PGx for clinical implementation by healthcare workers, clinicians, and researchers to ensure efficient, safe, and cost-effective pharmacotherapeutic treatment plans for patients.
Childhood Cancer Survivors Follow-up: A study from a Third-Level Hospital in a Low-Middle Income Country
Authors: Sheila Vega Espinoza
Published: March 2023

Introduction: Childhood cancer (CC) affects 1 in 285 children under the age of 20 in the United States. It has been shown that CC survivors experience short- and long-term effects from the treatment. In this study, the conditions and characteristics of CC survivors treated in the pediatric oncology/Hematology department of a third-level hospital are described. Methods: This was a retrospective, observational study. Information from the electronic files of the database of the pediatric oncology/hematology department from 2002 to 2017 was revised. Results: A total of 1,185 childhood cancer survivor files were revised, and the male sex was predominant. The mean age at the diagnosis was 6.6+5.08 years, at the time of the study the mean age, was 14.06+7.02 years. The most frequently reported cancer type was Acute Lymphoblastic Leukemia (22.4%). 93.3% of the patients did not have a relapse. Of the patients, 56.4% were still attending school and 3.4 reported having children. Discussion: Childhood cancer survivors require follow-up appointments where not only physical progress is assessed, but also long-term effects that may affect social and mental development.
Vaccine Induced Herpes Zoster in An Immunocompetent Child After 3 months of 1st Dose of Vaccination
Authors: Raja Fnu
Published: March 2023

Varicella zoster virus (VZV) is an enveloped double stranded linear virus, which belongs to the herpesvirus’s family. It can cause two clinically different forms of diseases, primary infection known as chicken pox and latent infection know as herpes zoster (Shingles). Primary infection presents with diffuse vesicular rash accompanied by fever, malaise, and pharyngitis. However, latent infection results from reactivation of dormant virus in an immunocompromised patient and presents with painful localized skin rashes called as shingles. Currently, in the US, 2 doses of live attenuated varicella vaccine are available to prevent VZV infection. One of the major side effects of vaccination are the rashes. We report a unique case of vaccine induced VZV infection in a previously healthy child that presents with vesicular rashes 3 months after 1st dose of vaccination. A 16-month-old child with past medical history of premature birth at 32 weeks, presented to the pediatric outpatient clinic with complains of well-demarcated, erythematous, dry rash on both labia. Parents denied fever, cough, or any other signs and symptoms associated with rashes. patient activity level was normal and oral intake was usual. PCR testing was performed was found to be negative for Herpes Simplex Virus-1 (HSV-1) and Herpes Simplex Virus-2 (HSV-2) and positive for VZV. Due to patient recent vaccination status, further classification of infection was needed to determine if the source of infection was wild type chicken pox or vaccine induced. A swab of one of the vesicular lesions was sent to the Ohio Department of Health, for vaccine vs wild-type strain PCR testing. The results were positive for Vaccine induced VZV infection. The patient was started on acyclovir therapy. On follow-up, the patient condition improved clinically. In pediatric populations, it is important to do extensive evaluation of rashes post vaccination as it can be occurred due to wild type, break through or it can be vaccine induced virus. Proper evaluation can significantly impact the management patients as they are maybe infectious and need to be isolated in wild type and breakthrough infection versus non-infectious in case of vaccine induced. After detailed clinical history and physical examination, it is important to investigate further through PCR testing to differentiate one category from another!
The Position of Premarital Property and Joint Property after Divorce: A Study of Premarital Agreement
Authors: Rimi Abdul Muthalib
Published: March 2023

This study aims to examine and analyze the position of the premarital property and joint property in the prenuptial agreement and the legal consequences after the divorce. This normative legal study uses a statute and comparative approaches with a literature study technique. The results show that premarital and joint property have different marital positions. Premarital property refers to property owned individually by the husband or wife before marriage. In contrast, joint property refers to property acquired during the marriage and jointly owned by husband and wife. At the time of the divorce, the joint property becomes the object of division, whereas the premarital property remains excluded from division unless regulated in the prenuptial agreement. If the divorce occurs without a prenuptial agreement, the division of joint property must be executed after a court decision is obtained, which has become final and binding. On the other hand, although the prenuptial agreement serves as a legal means of proof, the judge may ignore it for several reasons. That judge’s consideration can provide legal consequences for the prenuptial agreement in a divorce decision. Therefore, it is recommended that prospective spouses, notaries, and judges, need to understand the differences between premarital and joint property and the legal consequences related to divorce. Prospective spouses are advised to make clear and detailed prenuptial agreements regarding property division in the event of a divorce, thereby reducing potential conflicts and disputes. The notary should assist prospective spouses in drafting fair agreements under applicable laws. Judges, in turn, need to objectively consider prenuptial agreements and ensure that decisions align with both parties’ interests and the principles of justice.
Application of the Homotopy Perturbation Method for Differential Equations
Authors: Abdelhalim Necib , Imad Rezzoug , Abdelouahab Benbrahim
Published: March 2023

In this paper and in the first part of it, homotopy perturbation method is applied to solve second order differential equation with non-constant coefficients. The method yields solutions in convergent series forms with easily computable terms (the convergence of this series is demonstrated in this paper). The result shows that this method is very convenient and can be applied to large class of problems. As for the second part, we found a solution of Telegraph equation using the Laplace transform and Stehfest algorithm method. Next, we used method of Homotopy perturbation. Finally, we give some examples for illustration.
d-Tribonacci Polynomials and Their Matrix Representations
Authors: Kuloğlu Bahar , Özkan Engin
Published: March 2023

In this study, we define d-Tribonacci polynomials. Some combinatorial properties of the d- Tribonacci polynomials with matrix representations are obtained with the help of Riordan arrays. In addition, d- Tribonacci number sequence, which is a new generalization of this number sequence, has been obtained by considering Pascal matrix. With the help of Pascal matrix, two kinds of factors of d-Tribonacci polynomials were found. Also, infinite d-Tribonacci polynomials matrix and the inverses of these polynomials were found.
Appendix to “The Amazing Carrie Menkel-Meadow and What Wins When Passions Collide”
Authors: Love Lela
Published: March 2023

Appendix to “The Amazing Carrie Menkel-Meadow and What Wins When Passions Collide”
Zemstvo Tradition as a Particularly Valuable Intangible Cultural Heritage of the Russian North
Authors:   Laverov Federal Center for Integrated Arctic Research of the Ural Branch of the Russian Acade-my of Sciences, Terebikhin Nikolay N.
Published: March 2023

The article presents the scientific results obtained during the study of the zemstvo self-government tradition in the Russian North. This tradition is considered as a particularly valuable intangible cultural heritage. Its image-symbolical vocabulary (thesaurus) could be used in development of a regional strategy and local projects for the spatial development of the northern macroregion. The idea-concept of “zemstvo” (“mir”) holds a unique position within the conceptual sphere of the Russian North’ geocultural space. It is an ideal, canonical form of religious and sociocultural land management of Pomorye, which appears as reserved island-archipelago covered by web of autonomous, autocratical communities. The natural and cultural landscape of the Northern Russian mir is replete with “conciliar” and “sophian” semantics and symbolics of development, specialness, selfness, freedom, unitotality, triality, rhythmicity, gracefulness, wisdom. The cultural and semiotic mechanisms of the Slavic-Russian development of the lands and waters of the midnight Edge of the World are studied. Sacred geography and geosophy of “verhovskiy” and “nizovskiy” colonization streams of the North and the Arctic regions are revealed. Special attention is paid to the presentation of the experience and practices of preserving and adapting the sacred heritage associated with land management and consecration of territories and water areas of Pomorye (Kenozerskiy National Park, Naryan-Mar and Mezen Diocese, the project “Common Cause. Revival of Wooden Temples of the North”).
Spatial Organization of the National Economy in the Development of Non-Ferrous Metal Deposits in the Western Part of the Russian Arctic
Authors:   1 Luzin Institute for Economic Studies — Subdivision of the Federal Research Centre “Kola Science Centre of the Russian Academy of Sciences”, Belov Sergey V. , Skripnichenko Vladimir A.
Published: March 2023

The article analyzes the possibilities of studying the issues of the interterritorial distribution of the economy, taking into account maritime communications in the development of solid minerals in the west-ern sector of the Russian Arctic on the basis of interaction of national and corporate interests at the re-gional level. Relatively large deposits of solid minerals are located in this region. The development of non-ferrous metal deposits, taking into account the requirements of rational nature management, is the engine of economic development in the western Arctic regions of Russia. An urgent task is the scientific substantiation of favorable conditions for the comprehensive development of marine activities, necessary technological and human potential, economic benefits from the use of domestic marine potential, mineral resources and spaces of the western part of the Russian Arctic in the interests of national security, economic development and improving the welfare of citizens of the Russian Federation. The information framework is based on the experience of developing lead-zinc ore deposits in the Arctic. The topic under study is consistent with the provisions of regional and sectoral economics, as well as spatial economics. This scientific basis makes it possible to substantiate the spatial organization of the national economy in the development of solid minerals in the western part of the Russian Arctic.
Mit Forschungszulagengesetz wettbewerbsfähig bleiben
Authors: Wessels Markus
Published: March 2023

In diesen mit vielen Unwägbarkeiten verbundenen Zeiten müssen Unternehmen auf jeden Cent achten, um der Energiekrise und der hohen Inflationsrate begegnen zu können. Das Forschungszulagengesetz bietet dafür eine gute Möglichkeit.
La mente humana y los retos de la educación universitaria
Authors: Tacca Puma José
Published: March 2023

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The clinical manifestations and treatment strategies of congenital myasthenic syndrome associated with endplate development and maintenance deficiency: a systematic review and meta-analysis of case reports and case series
Authors:   Huashan Hospital, Fudan University, Gu Xinyu , Zhao Chongbo , Xi Jianying
Published: March 2023

Review question / Objective: We aimed to investigate the demographic features, clinical manifestations and treatment strategies of CMS associated with the Agrin/LRP4/MuSK/Dok7/Rapsyn signaling pathway. Condition being studied: As with all other rare disorders, there has been few large cohort study or clinical trials focusing on CMS associated with endplate development and maintenance deficiency. In such case, systematic reviews are required to help guide the clinician’s diagnostic test and therapeutic strategy, so as to avoid misdiagnosis and inappropriate treatment.
Specific Nature of Price Competition at an Auction of Renewable Energy Sources (RES) in the EU
Authors:   Lomonosov Moscow State University, Podlesnaya Alina V. ,   PJSC NOVATEK
Published: March 2023

The article is devoted to the efficiency estimation of the deployment of RES auctions in the EU to reduce the RES generation cost and consequently the cost of its state support. The relevance of the study is due to the fact that to improve the efficiency of state support for RES generation in the EU, as the main driver of its development, since 2017 EU member states have been required to set its level at auctions. To achieve this goal, we analyzed the dependence of RES electricity prices at auctions in 14 EU member states (and separately in Germany and France) on the ratio of volume participating with volume requested and volume awarded as well as technology neutrality/specificity of auctions (number of competing technologies). The following results were obtained in the study. Firstly, both in the EU, as well as in Germany and France RES electricity prices were lower at auctions where volume participating exceed volume requested rather than volume awarded. The following conclusions were drawn. Competition at the auction arises when not all announced projects will receive support within the allocated amount of funding. Thus, more correct indicator of competition level at the auction is oversubscription of the auction. Secondly, in comparison to the EU, in Germany and France lower RES electricity prices were set at technology neutral auctions. Competition of technologies should lead to deployment of the most cost-efficient RES generating plants; therefore, the conclusion is drawn that in the absence of risks of suboptimal results priority should be given to technology neutral auctions.
The Evolution of Antitrust Regulation of Joint Venture Agreements
Authors:   Lomonosov Moscow State University, Shastitko Andrey E. ,   IAER RANEPA, Pavlova Natalia S. ,   Lomonosov Moscow State University;  IAER RANEPA
Published: March 2023

Cooperation agreements between competitors can be an important tool for markets to adapt to external shocks, whether those are the consequences of a pandemic or economic sanctions. In this regard, the discussion of approaches to evaluating such agreements for admissibility from the point of view of antimonopoly legislation under current conditions is relevant. The purpose of the article is to assess the current state of antimonopoly control of cooperation agreements in Russia. To do this, we use the tools of the new institutional economic theory to analyze the history of the development of the regulation of such agreements. We reveal how modern sources of possible type I enforcement errors (the erroneous prohibition of agreements that actually contribute to the growth of public welfare) are connected with the history of institutional changes in the rules governing the analysis of cooperation agreements from the point of view of antimonopoly legislation. In particular, we show that the approaches to the analysis of cooperation agreements developed during the period of validity of a specific set of rules in 2011–2015 and summarized in the Clarifications of the Presidium of the FAS Russia on the procedure and methodology for analyzing cooperation agreements (2013) currently create an overly strict control regime for such agreements after the changes in the antimonopoly law that took place in 2015. The importance of solving this problem is demonstrated in light of the ability of companies to use cooperation to mitigate the consequences of external shocks, including economic sanctions. Structural alternatives to the control of such agreements are formulated that are applicable to various actual forms of agreements between competitors, which could contribute to a better adaptation of market participants to changing conditions.
Challenges and Opportunities for Giant Freshwater Prawn Culture through Participatory Learning and Fish Farmer Engagements
Authors:   WorldFish-PCO, Tambalque III Hermogenes , Perez Maripaz ,   WorldFish - Philippine Country Office, SEARCA Building, Los Banos, Laguna, Nieves Plutomeo ,   Bicol University - Tabaco Campus, Corre Valeriano ,   UPV-Iloilo, Duarte Jude ,   Southern Leyte State University, Pulido Neil ,   Dipolog School of Fisheries, Dejarme Henry ,   MSU-Naawan, Tanay Dennis ,   National Fisheries Research and Development Institute, Garces Len ,   WorldFish-PCO
Published: March 2023

This paper provides a review of on-farm studies conducted to explore the viability of giant freshwater prawn (Macrobrachium rosenbergii, locally known as ulang), culture in six regions in the Philippines. We adopted a participatory action learning approach aimed at improving pond productivity through engagement of 17 small-scale fish-farmer cooperators to adopt different ulang culture systems—ulang monoculture, ulang-rice polyculture, and ulang-tilapia polyculture. This paper focuses on comparing the production and profitability of ulang monoculture and ulang-tilapia polyculture. The cooperators were guided to follow proper protocols in pond preparation, feeding, and water management. Results showed an average survival rate of 65 percent for ulang monoculture; and 59 percent and 77 percent survival rates for ulang and tilapia in polyculture system, respectively. The major problems encountered across regions were unavailability of post-larvae; distance of post-larvae source; water availability; presence of predators; and inconsistent implementation of technical interventions by the cooperators. This paper also presents research and policy recommendations toward sustainable development of freshwater prawn culture which include establishment of a network of hatcheries and broodstock development; technology promotion and extensions services; and improving value chains and market strategy.
Book Review | China's Peasant Agriculture and Rural Society: Changing Paradigms of Farming by Jan Douwe van der Ploeg and Jingzhong Ye
Authors:   Department of Financial and Business Systems, Faculty of Agribusiness and Commerce, Lincoln University, New Zealand, Gan Christopher
Published: March 2023

This book integrates current research in peasant agriculture with appropriate and relevant cases, and practical relevant examples. The beauty of the book lies in the individual chapters that delve into the density issues of Chinese peasant agriculture in readable and entertaining style. I see this book as a perfect outlet for readers who are curious about Chinese peasant agriculture and for students to explore this material through both assigned and optional reading.
Maize Supply Response in Vietnam
Authors: Huong Nguyen Van , Yorobe Jose
Published: March 2023

This study used a supply response model to determine factors affecting maize supply in Vietnam. It estimated response coefficients from semi-annual time-series data for the period 1986-2011. Using three criteria, it chose the rational expectation hypothesis supply response model (Model I) with the separated price expectation formation hypothesis according to the information set at time (t-1) to estimate the supply response model for maize. Farmers used the available information set to form their expected price. Estimated parameters’ results in Model I indicate that the farmers' supply had a positive response to the expected price of maize, but was negative to that of cassava. This means that maize and cassava are close substitutes in the supply response models. Maize production also positively responds to the amount of fertilizer per hectare, maize area, one-period lagged investment, irrigation, trend variable, and agricultural extension policy. Recommended policies include: enhancement of the judicious use of fertilizers and possible establishment of local factories; increase in maize area by changing the crop structure and multiple cropping with long-term industrial trees like perennials and fruit trees; improvement of the irrigation system in two deltas and in high production regions; increase in government support to farmers; increase in government spending on research and development of new maize varieties; and improvement of the extension system to provide farmers the needed market and technological information.
Challenges and Opportunities in Implementing the Ecosystem Approach to Small-scale Fisheries Management (EAFM) in Misamis Occidental, Philippines
Authors:   Southeast Asian Regional Center for Graduate Study and Research in Agriculture (SEARCA), Santos III Lope , Callanta-Mariano Leslie ,   Southeast Asian Regional Center for Graduate Study and Research in Agriculture (SEARCA), Tallada Alvin ,   Southeast Asian Regional Center for Graduate Study and Research in Agriculture (SEARCA), Garces Len ,   WorldFish - Philippine Country Office, Perez Maripaz ,   WorldFish - Philippine Country Office, Buendia Idohna Leah ,   WorldFish - Philippine Country Office, Alolod Angelito ,   WorldFish - Philippine Country Office, Saceda Judahlyn ,   WorldFish - Philippine Country Office
Published: March 2023

This paper presents the challenges and opportunities of small-scale fisheries management in Misamis Occidental, especially in the coastal municipalities of Aloran, Jimenez, Lopez Jaena, Panaon, Plaridel, Sinacaban, Tudela, and Oroquieta City. A site diagnosis was conducted as part of the participatory diagnosis and adaptive management framework to characterize the governance of small-scale fisheries in the area and to determine the potential for adopting the ecosystem approach to fisheries. Stakeholders identified, in order of priority, the following issues affecting fisheries and coastal resource management in Iligan Bay: depleted fishery resources, lack of alternative livelihood, and limited institutional capabilities. In a united response, the local government units in the area formed the Iligan Bay Alliance of Misamis Occidental, through which they explore opportunities to address issues and to restore and sustain the fisheries in Iligan Bay.
Profitability and Competitiveness of Rice Farming in Malaysia: A Policy Analysis Matrix
Authors:   Universiti Teknologi MARA, Malaysia Georg-August University of Goettingen, Germany, Fatah Fazleen Abdul , Cramon-Taubadel Stephan Von ,   Georg-August-University of Goettingen, Germany
Published: March 2023

In recent years, the Malaysian rice sector has experienced structural changes to improve its competitiveness within a dynamic environment that is influenced by political, technical, economic, and international trade challenges. Using a policy analysis matrix and a rich dataset on rice producing households in four of Malaysia’s granary areas, the competitiveness of rice production in Malaysia is analyzed. The empirical results show that rice production is competitive in three of the four granary areas, the exception being Ketara granary area. To fully understand the importance of the competitive farms, they must be identified and studied by further research using disaggregated data. The finding suggests that government policy should focus on encouraging structural changes capable of enabling the local farms to grow enough to earn sufficient income, generate social profits, and thus improve the sector's competitiveness.
Determinants of Climate Change Adaptive Behavior in Coastal Communities in Southeast Asia
Authors:   Department of Economics, University of the Philippines Los Banos, Los Banos, Laguna, Sajise Asa Jose , Arias Jaimie Kim ,   Department of Economics, University of the Philippines Los Banos, Los Banos, Laguna, Ramirez Paul Joseph ,   WorldFish - Philippine Country Office, SEARCA Building, Los Banos, Laguna, Perez Maripaz ,   WorldFish - Philippine Country Office, SEARCA Building, Los Banos, Laguna, Zamora Glaiza ,   WorldFish - Philippine Country Office, SEARCA Building, Los Banos, Laguna
Published: March 2023

This study sought to understand the determinants of autonomous adaptation of households in coastal communities in three countries (Indonesia, the Philippines, and Vietnam) as regards climate change. The study’s main innovation is its focus on households facing a confluence of related hazards, a context that is unique to coastal communities. The study tackled the interrelated hazards of coastal erosion, flooding, and saltwater intrusion, and used a multivariate probit model to analyze the determinants. Regression results show that households adapt or respond autonomously to a combination of hazards. In fact, the econometric model of joint decision cannot be rejected by the data. Geographical differences were observed in adaptation patterns, implying that households react rationally to the degree of threats from the hazards. Like in some literature, the study found evidence that planned adaptation may crowd out private or autonomous adaptation. Likewise, trust increases the likelihood of self-insurance and self-protection, especially against extreme events that are either recurring or permanent. Finally, the households’ adaptive capacity depends partly on the type of hazard and has a gender dimension. In recurrent extreme events, the abundance of male labor increases the likelihood of adaptation. In permanent and creeping hazards such as saltwater intrusion, the abundance of female labor increases the likelihood of adaptation.
Testing of the Seasonal Unit Root Hypothesis in the Price Indices of Agricultural Commodities in India
Authors:   Dept. of Economics, IBS, Hyderabad, IFHE University, Hyderabad, Tiwari Aviral Kumar , Dutta Subhendu ,   Dept. of Economics, IBS, Hyderabad, IFHE University, Hyderabad, Dash Aruna Kumar ,   Dept. of Economics, IBS, Hyderabad, IFHE University, Hyderabad
Published: March 2023

The study analyzed the persistence of shocks to the seasonal time series of the price indices of selected agricultural commodities in India. The seasonal unit root test procedure proposed by Hylleberg et al. (1990) and Beaulieu and Miron (1992) were used for 10 major price indices of agricultural commodities. The study covered the period January 2000 to January 2013. Overall results provide significant and robust evidence rejecting the presence of unit roots at all seasonal frequencies for cereals; condiments and spices; eggs, meat, and fish; pulses; and vegetables. For the rest of the commodities studied, evidence indicates that the seasonality present is partly deterministic and partly stationary stochastic. These findings have important policy implications for policymakers and research analysts.
Estimulación del pensamiento crítico para replantear la educación
Authors: Albarracín Granda María José , Granda Uyaguari Julia Margarita , Granda Ullaguari Libia Azucena , Granda Uyaguari Guicela Beatriz
Published: March 2023

El estudio que se desarrolló ha tenido como objetivo, desarrollar una búsqueda

Sistemática de información relevante sobre el pensamiento crítico de los estudiantes, así como el análisis de información que busca replantear los procesos educativos, para lo cual se han consultado diversas plataformas virtuales, especializadas en información científica y estudios y artículos relacionados con las variables planteadas, llegándose a encontrar 468 documentos relacionados con las variables, siendo seleccionados bajo el esquema PRISMA, el cual llegó a clasificar 35 documentos relevantes para la investigación. Los resultados indicaron que el pensamiento crítico contextual es el más utilizado con un 31% seguido del pensamiento sustantivo con un 26%, por otro lado para el replanteamiento de la educación la característica más importante ha sido la equidad con un 31% y la pertinencia con un 2,3%
Psicología Evolutiva del Periodo Sensoriomotor
Authors: Recalde Rojas Gladys Vanessa , Duque Granados Rocío Alejandra , Cadena Palacios Cristina Nataly , Araujo de Rodríguez Ismenia del Carmen
Published: March 2023

Psicología Evolutiva del Periodo Sensoriomotor
PSYCHOLOGICAL WELL-BEING AND RESILIENCE AMONG COVID RECOVERED PATIENTS
Authors: Gupta Kavita , Parimal B.S. , Oza Noopur
Published: March 2023

The present cross-sectional correlational study was conducted with an aim to investigate the relationship between Psychological well-being and Resilience among Covid Recovered Patients. The data was collected through convenient sampling and a sample of 142 respondents from Gujarat state in the age range of 18-60 years participated by filling up Socio- demographic measure, the Ryff’s Psychological Well-being, and The Resilience Scale questionnaire. The Questionnaires were converted into Gujarati language and then validated by the experts. Spearman’s rho correlation and independent sample t-test were performed to determine the relationship between psychological well-being and Resilience among the research participants. Data was analysed statistically at the level of p < 0.05. The results from the study showed that there was a statistically significant Positive relationship between Psychological well-being and Resilience. Prospective longitudinal studies are needed to address and encourage researchers and clinicians to give as much attention to the development and maintenance of psychological well-being in the face of serious illness as they do to the aetiology and treatment of psychiatric symptoms.
Histopathological Analysis of Tongue Lesions and Distribution by Age Groups
Authors: ALTINTAŞ Mustafa
Published: March 2023

Aim: To retrospectively evaluate the histopathological characteristics of biopsies taken from tongue lesions and compare the results with current literature.
Material and Methods: Histopathological results of biopsies taken from 163 patients with suspected tongue lesions between January 2017 and January 2022 were retrospectively reviewed. The results were evaluated in different age groups.
Results: Seventy-two (44.2%) of the patients were male and 91 (55.8%) were female. The mean age of the patients was 47.76±17.33 years. The lesion was benign in 135 (82.8%) patients, precancerous in 4 (2.5%), and malignant in 24 (14.7%).
Of the 135 patients with benign findings, squamous papilloma was detected in 33 (24.4%) patients and irritation fibroma in 19 (14.1%). Ulcer/inflammatory granulation tissue was detected in 18 (13.3%) patients, parakeratosis/acanthosis in 14 (10.4%), fibroepithelial polyp in 14 (10.4%), and pseudoepitheliomatous hyperplasia in 9 (6.7%). Less frequently, lymphoid hyperplasia, neurofibroma, mucocele, and verruca vulgaris were detected in 1 (0.7%) patient each. Squamous cell carcinoma was detected in all patients with malignancy. When evaluated according to age groups, it was found that the patients were most commonly in the 50–59 (27.6%) age group, followed by the 40–49 (19.6%) age group.
Conclusion: The results show that most tongue lesions are benign. It should be noted that not every mass in the tongue is cancerous, but leukoplakic and ulcerated areas can be malignant. Due to the rapid metastasis of tongue lesions, early diagnosis and treatment may contribute significantly to the prognosis of patients.
Evaluation of Prolonged Rt-Pcr Positivity and Viral Load in COVID-19 Patients
Authors: URKMEZ Fatma Yekta , EROL Ozlem , POLAT Esra , KAYGUSUZ Sedat
Published: March 2023

Aim: Real-time reverse transcription polymerase chain reaction (RT-PCR) test is used in the diagnosis of COVID-19. It was aimed to evaluate the factors affecting the viral conversion time, to examine the relationship between viral load, and to determine other factors that may be associated with viral load. Material and Methods: Patients were hospitalized between 15.03.2020-01.08.2020, and viral conversion detected were evaluated retrospectively. Patients were divided into two according to viral conversion time (0-14 days vs >14 days). Results: 349 patients were included in the study (284 vs 65 patients). The age and gender characteristics were similar. Prolonged PCR positivity group had more death (p=0.036) and lower cycle-threshold (CT) value (p=0.017). In the examination of CT values of 246 patients, 228 patients with viral conversion and 18 patients without viral conversion due to death, the CT value was found to be lower, therefore the viral load was higher in patients over 60 years of age (p=0.006), in the presence of cardiovascular system disease (p<0.001) and in patients who died (p<0.001). Conclusion: Prolonged PCR positivity may indicate excess viral load and adverse outcomes. An evaluation including the patient's age, CT value, comorbid conditions, and viral conversion time can give an idea about the prognosis.
Comparison of Feature Selection Methods in Breast Cancer Microarray Data
Authors: AGRAZ Melih
Published: March 2023

Aim: We aim to predict metastasis in breast cancer patients with tree-based conventional machine learning algorithms and to observe which feature selection methods is more effective in machine learning methods related to microarray breast cancer data reducing the number of features.
Material and Methods: Feature selection methods, least squares absolute shrinkage (LASSO), Boruta and maximum relevance-minimum redundancy (MRMR) and statistical preprocessing steps were first applied before the tree-based learning conventional machine learning methods like Decision-tree, Extremely randomized trees and Gradient Boosting Tree applied on the microarray breast cancer data.
Results: Microarray data with 54675 features (202 (101/101 breast cancer patients with/without metastases)) was first reduced to 235 features, then the feature selection algorithms were applied and the most important features were found with tree-based machine learning algorithms. It was observed that the highest recall and F-measure values were obtained from the XGBoost method and the highest precision value was received from the Extra-tree method. The 10 arrays out of 54675 with the highest variable importance were listed.
Conclusion: The most accurate results were obtained from the statistical preprocessed data for the XGBoost and Extra-trees machine learning algorithms. Statistical and microarray preprocessing steps would be enough in machine learning analysis of microarray data in breast cancer metastases predictions.
Effects of Smoking on Pattern Visual Evoked Potentials
Authors: ESKİ Mehmet Tahir , YABALAK Ahmet , ŞAHAN Halime , AYASLI Alper , SEZER Taha
Published: March 2023

Aim: The aim of the study is to get a better understanding of the side effects of smoking by evaluating the effect of recently elevated smoking rate on Visual Evoked Potentials (VEP) and to determine whether it is necessary to use different normals when evaluating the VEP measurements of smoking patients.
Material and Methods: The patients who have applied to our ophthalmology and neurology outpatient clinics during 2021-2022 are included to the study. Detailed ophthalmologic examination of the patients as well as their VEP test is completed followed by a dilated fundus examination assessment. The patients with normal results are included to the study. The smoking rate is calculated on pack/year basis. Pattern VEP (PVEP) recording is performed based on Keypoint (Dantec, Denmark) and International Society for Clinical Electrophysiology of Vision (ISCEV) criteria. Data obtained through the study are analyzed by SPSS 21.0 version software. Countable variables with normal distribution between two independent groups are analyzed with Independent Sample T test whereas variables without normal distribution are analyzed with Mann Whitney U test. Chi-square test is used for comparing categorical variables.
Results: 71 patients were included to the study where 33 of them were placed in smoking group and 38 in non-smoking group (control group). Smoking group had a yearly cigarette package consumption of 5.20±8.93 (0.2-40). VEP latency and amplitude changes were compared and according to the obtained results; there was P100 latency prolongation in between left and right eye of the patients in the control group and smoking group but it did not have any statistical significance (p=0.910 and p=0.697 respectively). There was no statistically significant difference in either left nor right eye in terms of smoking and P100 and N70 latencies (p=0.707, p=0.838, p=0.717 and p=0.621 respectively). Similarly, there was no significant correlation between yearly package consumption and P100 and N70 latencies and amplitudes of left and right eyes (p=0.503, p=0.410, p=0.776 and p=0.940 respectively).
Conclusion: No significant effect of smoking is found on VEP values thus leading us to believe that the same normal intervals can be used in the evaluation of VEP results of both smoking and non-smoking patients.
Development of the Orbit and Eyeball during the Fetal Period
Authors: BİLKAY Cemil , KOYUNCU Esra , DURSUN Ahmet , ÖZTÜRK Kenan , ÖZGÜNER Gülnur , TÖK Levent , TÖK Özlem , SULAK Osman
Published: March 2023

Aim: We aimed to investigate the morphometric development of the orbit and eyeball in the fetal period.
Material and Methods: The present study was carried out on 136 fetal eyes (86 males, 50 females) obtained from 68 fetuses aged between 15-40 gestational weeks. In this study, the area, height, width, volume, depth, and circumference parameters of the orbit were measured, while the anteroposterior and transverse diameters, weight and volume parameters of the eyeball were measured. Also, the diameter at the place where the optic nerve enters the eyeball was measured.
Results: It was determined that all parameters increased during the trimesters and there was a statistically significant difference between the trimesters in all parameters. There was no statistically significant difference in all parameters in terms of gender. In the comparison of the right and left sides, orbital area (p<0.011), orbital circumference (p<0.048) and orbital width (p<0.048) were higher on the right side. There was no difference between the parties in any of the parameters related to the eyeball (p>0.05). However, the diameter of the optic nerve was higher on the left side (p<0.001).
Conclusion: The data we obtained will be very useful in evaluating the pregnancy follow-up by imaging methods such as ultrasonography or magnetic resonance, in the early diagnosis of malformations or diseases, and in planning the treatment.
Comparison of Cardiovascular Disease Risk Indicators in Bipolar Disorder Patients with Healthy Controls
Authors: KAPICI Yaşar , AYHAN Selçuk , GUC Bulut , TEKİN Atilla
Published: March 2023

Aim: It is important to assess the likelihood of cardiovascular disease in patients with bipolar disorder (BD). In this study, indicators of increased cardiovascular disease risk on electrocardiogram (ECG) and laboratory were evaluated.
Material and Methods: In the present investigation, we studied the demographic details, ECG variables, and blood test results of 90 healthy controls (HC) and 97 patients we followed for BD diagnosis.
Results: Age and gender trends were similar between the BD and HC groups (p=0.844 and p=0.664). BD had a higher mean number of fragmented QRS (fQRS) than the HC group, and fQRS was more frequent (p=0.002 and p=0.007). The frontal QRS-T angle was wider in the BD group than it was in the HC group (p=0.038). Monocyte-to-lymphocyte ratio (MLR), monocytes to high-density lipoprotein cholesterol (HDL-C) ratio (MHR), and atherogenic index of plasma (AIP) were statistically greater in BD patients (p=0.021, p<0.001, and p<0.001).
Conclusion: In brief, the report indicates that impaired ventricular repolarization is related to an elevation in the frontal QRS-T angle in BD. As a result, BD patients have a greater risk of cardiovascular mortality and ventricular arrhythmias. As a result, clinicians ought to have a greater understanding of the frontal QRS-T angle and conduct an ECG examination on regular controls.
Futbolda Bazı Teknik Parametrelerin Maç Konumu, Maç Sonucu ve Lig Sıralamasına Göre İncelenmesi (2021/2022 Sezonu Türkiye Futbol Süper Ligi Örneği)
Authors: GÜRKAN Oğuz
Published: March 2023

Bu çalışma, 2021/2022 sezonunda Türkiye futbol süper liginde oynanan 380 müsabakayı maç konumuna, maç sonucuna ve lig sıralamasına göre analiz etmek amacıyla yapılmıştır. Maçların verileri www.tr.matchstudy.com web sayfasından gerekli izin alınarak temin edilmiştir. Çalışmada değerlendirilen tüm veriler SPSS paket programına girilmiş olup, verilerin ortalama ve standart sapma gibi tanımlayıcı değerleri ortaya konmuştur. Yapılan shapiro-wilk normallik testi sonucu verilerin normal dağılama uygun olmadığı tespit edilmiştir. Bunun sonucunda da galibiyet, mağlubiyet ve beraberlik ile sonuçlanan müsabakaların karşılaştırılmasında nonparametrik testlerden Kruskal Wallis-H testi yapılmış olup, gruplar arasında farklılık çıkması durumunda da farkın hangi gruplardan kaynaklandığı ortaya koymak için post hoc Tamhane’s T2 testi yapılmıştır. İç saha ve dış sahada oynanan müsabakalar ile ligi ilk 10 (1-10) ve son 10 (11-20) sırada tamamlayan takımların karşılaştırılmasında da nonparametrik testlerden Mann Whitney-U testi yapılmıştır. Elde edilen bulgular sonucunda müsabakalardan galibiyet ile ayrılan takımların toplam şut, olumlu şut, rakip ceza alanında toplam pas, rakip ceza alanında olumlu pas ve ceza alanına atılan olumlu top ortalamalarının maçlardan beraberlik ve mağlubiyet ile ayrılan takımların ortalamalarından daha yüksek ve aynı zamanda da istatistiksel olarak anlamlı olduğu tespit edilmiştir (p<0.05). İç sahada oynayan ve ligi ilk 10’da tamamlayan takımların belirtilen tüm parametre ortalamalarının, deplasmanda oynayan ve ligi son 10’da tamamlayan takımların ortalamalarından daha yüksek ve aynı zamanda da istatistiksel olarak anlamlı olduğu tespit edilmiştir (p<0.05).
Evaluation of Play Skills of Primary School Students Playing Traditional Children's Games
Authors: TEMEL Ahmet , KANGALGİL Murat , MAMAK Hüdaverdi
Published: March 2023

This study was conducted to evaluate the physical activity levels and game performances of primary school students participating in traditional children's games. A survey model, one of the quantitative research methods, was used in the research. The sample of the research consisted of 16 students who participated in the final matches of traditional children's games in the 2021-2022 academic year and were determined according to the game region. In the research, data were collected by using the “System for Observing Fitness Instruction Time (SOFIT)” and “Game Performance Assessment Instrument (GPAI)” through the behavioral observation method. Descriptive statistics, Mann Whitney U test, and correlation analysis were used in the analysis of the data. According to the research findings, while the students showed the most standing behavior, the level of moderate-vigorous physical activity (MVPA) was at the desired level. It has been determined that the GPAI components are at a medium level in the case of skill application, while the other components are at a good level in decision-making, support, game participation, and performance. No significant difference was found in MVPA and game performance by gender. While a positive significant relationship was found between MVPA and the GPAI component of game performance, no significant relationship was found between MVPA and other GPAI components. As a result of the research; it was concluded that primary school students playing traditional games had good MVPA levels and sufficient game skills. Based on the results of the research, it can be suggested to use traditional games in physical education lessons and to create lesson content for the development of tactical awareness of students.