bluuebunny/crossref_metadata_2025 huggingface dataset:
High-resolution Carbon cycling data from 2019 to 2021 measured at six Austrian LTER sites
Authors: Dirnböck Thomas , Bahn Michael , Diaz-Pines Eugenio , Djukic Ika , Englisch Michael , Gartner Karl , Gollobich Günther , Hofbauer Armin , Ingrisch Johannes , Kitzler Barbara , Knaebel Karl , Kobler Johannes , Maier Andreas , Wohner Christoph , Offenthaler Ivo , Peterseil Johannes , Pröll Gisela , Venier Sarah , Zechmeister Sophie , Zolles Anita , Glatzel Stephan
Published: June 2024

Abstract. Seven long-term observation sites have been established in six regions across Austria, covering major ecosystem types such as forests, grasslands and wetlands across a wide bioclimatic range. The purpose of these observations is to measure key ecosystem parameters serving as baselines for assessing the impacts of extreme climate events on the carbon cycle. The data sets collected include meteorological variables, soil microclimate, CO2 fluxes and tree stem growth, all recorded at high temporal resolution between 2019 and 2021 (including one year of average climate conditions and two comparatively dry years). The DOIs of the dataset can be found in the data availability chapter. The sites will be integrated into the European Research Infrastructure for Integrated European Long-Term Ecosystem, Critical Zone, and Socio-Ecological Research (eLTER RI). Subsequently, new data covering the variables presented here will be continuously available through its data integration portal. This step will allow the data to reach its full potential for research on drought-related ecosystem carbon cycling.
A Holocene alpine seismic chronicle from Lake Aiguebelette (NW French Alps)
Authors: Banjan Mathilde , Crouzet Christian , Jomard Hervé , Sabatier Pierre , Marsan David , Messager Erwan
Published: June 2024

Abstract. Lake sediments are valuable archives and can help construct a chronology of event deposits induced by seismic events. Such a chronology can be used to better understand the recurrence times between seismic events over longer periods than those covered by historical seismicity catalogs. However, only a few studies in lake palaeoseismology have focused on areas with moderate seismicity. This study aims to improve the catalog of paleoseismological archives in the front of the Western Alps. In this part, new multi-proxy data from the sedimentary archives of Lake Aiguebelette (France) allow the identification of 32 homogenites (thickness ≥ 0.5 cm) interpreted as of coseismic origin over the Holocene. An age model based on short-lived radionuclides, paleomagnetic data and radiocarbon ages constrains the chronology of sedimentary deposits in the deep basin of Lake Aiguebelette. Among these homogenites, several were deposited at time intervals compatible with historical seismic events. To correlate the historical seismic events likely to have generated the event deposits identified in the sedimentary sequences of the deep basin of Lake Aiguebelette, the Earthquake Sensitivity Threshold Index (ESTI) method is used. Historical seismicity catalogs with uncertainties about intensities and epicenter coordinates for earthquakes make correlations to event deposits difficult. To better understand which seismic events may have been archived, a relative comparison was conducted between the pseudospectral acceleration (PSA) values calculated for each event in the FCAT-17 seismic catalog and for two distinct frequencies. Based on this PSA approach, for higher frequencies (5 Hz), the contribution of nearby and moderate events is significantly stronger than that of strong and distant events in the lake sequence of Aiguebelette. Thus, the chronicle established based on the event deposits archived in Lake Aiguebelette sediment is interpreted as representative of local events (epicentral distance to the lake < 50 km). Recurrence intervals between the deposition of event layers do not follow a specific distribution (log-normal, Weibull, gamma or exponential) but might be a combination of several distributions. This suggests possible coexistence of several processes over the Holocene, impacting the evolution of the seismicity in this area.
Exploring social skills in sports: a comparative analysis between individual and team athletes among students
Authors: Chafaa Amina
Published: June 2024

Social skills are essential for individuals, enabling positive engagement with their environment, numerous studies have underscored the contribution of sports in cultivating such skills. This study aims to explore level of social skills and explore differences among individual and team athletes. The Alwan Scale (2011), comprising four dimensions, was validated for its psychometric properties and then administered to a random sample of 143 student athletes at the Institute of Sports Science and Physical Activity Technologies (STAPS) during the academic year 2022-2023. Among the participants, 68 were engaged in individual sports, and 75 participated in team sports, with an average age range of (20-28). Data analysis was conducted using SPSS version. The results indicated a high level of social skills and their dimensions, with no significant differences between individual and team sports and the Point-Biserial correlation test indicate that there is no significant relationship between the type of sport and students.
Keywords: social skills, individual sports, team sports, athletes, students.
Istiŷŷa, la Écija emiral, a través del análisis de feluses, contextos arqueológicos y sellos de conquista: el valor histórico de los ocultamientos de moneda
Authors: Martín Escudero Fátima , Campos-López Teresa , Romo Salas Ana
Published: June 2024

Esta propuesta participa del análisis de los feluses y sellos o precintos como fuentes para la comprensión del proceso de conquista, arabización e islamización de al-Andalus (siglos VIII-IX d. C.). Se destaca que el modelo de conquista en al-Andalus resultó en un asentamiento diferenciado de los grupos y de sus relaciones con la población autóctona. El objetivo principal es analizar este proceso a través del estudio de fuentes numismáticas, contextualizándolos arqueológicamente como datos cruciales para la comprensión histórica de los procesos vinculados a este momento.
El valor de las piezas encontradas en ocultamientos y su relevancia en contextos arqueológicos, nos da pie para analizar el conjunto localizado en uno de los enterramientos de la Plaza de España de Écija (Sevilla), una de las necrópolis islámicas más importantes de la península. Así, se constata que tras la batalla de Écija - Istiŷŷa, el territorio fue asignado como botín a los bereberes. Sin embargo, pronto se produce un cambio poblacional, y pasa parte a manos de la población árabe, aumento poblacional que se refleja en una creciente presencia de moneda andalusí. Además, la contextualización de estas monedas, como un ocultamiento, nos proporcionaría la posibilidad de constatar el primero de ellos realizado con feluses.
Unveiling Inequality: Mapping Asset Disparities in Azad Jammu and Kashmir (Pakistan)
Authors: Naveed Tanveer Ahmed , Ullah Sami , Mughal Sundus Aijaz , Rizvi Badar
Published: June 2024

The main objectives of this study are to construct a valid and reliable asset index at the household level for 10 districts of Azad Jammu and Kashmir (AJK) by using Multiple Indicators Cluster Survey micro-data and to estimate economic disparities by calculating Gini-coefficient and Palma Ratio. The asset index is considered a better estimate than expenditures or current household income to gauge a household’s living standard and its potential resilience to deal with economic shocks. The dimensional structure of assets is assessed by applying Exploratory Factor Analysis (EFA) and Tetrachoric Principal Component Analysis (PCA). Further, this paper has applied Classical Test Theory (CTT) and Item Response Theory (IRT) to ensure the reliability of the household-based asset index. Furthermore, the Gini-coefficient and Palma ratios are estimated by using the composite household-based asset index to estimate economic disparities in all 10 districts of AJK. The dimensional structure of assets, reliability, and validity analysis suggest to use 21 assets (out of 30 items) to construct the household-based asset index. The nine items (assets) are excluded from the analysis to avoid systematic errors and random errors. The results show that districts Bhimber and Mirpur have achieved the highest average asset scores, which are 0.62 and 0.64 respectively. The score of the Gini-coefficient index and the Palma ratio analyses shows that the asset distribution in the districts Neelum and Haveli are highly unequal. The Gini-coefficient is highly responsive to midpoint distribution while the Palma ratio concentrates more on top and bottom distribution, and it ignores the middle 50 percent from the analysis. Interestingly, both approaches have produced similar district rank ordering because we have adopted a systematic process for construct validity and reliability to minimize measurement errors.
Usulan Integrasi Data Absensi dengan Teknologi Fingerprint menggunakan Server Internal Perusahaan Sebagai Solusi Penerapan Indi 4.0 di PT Fuji Seat Indonesia
Authors: Agustin Desy , Arohman Abdul Wahid , Mustofa Mustofa , Salati Dianasanti , Lai Kenny , Putra Adhitya Nugraha Duwan , Simajuntak Felizia Gabriella
Published: June 2024

Revolusi industri 4.0 mendorong integrasi teknologi cyber dalam ranah industri, termasuk penggunaan Big Data, Cloud Computing, manufaktur aditif, Internet of Things (IoT), dan kecerdasan buatan. Perusahaan-perusahaan, termasuk PT Fuji Seat Indonesia, mulai menerapkan teknologi untuk memperbarui sistem absensi karyawan dari yang awalnya manual menjadi berbasis digital, menggunakan teknologi fingerprint, sensor mata, atau pengenalan wajah. Dalam konteks ini, integrasi data absensi dengan teknologi fingerprint melalui Server Intranet Internal Perusahaan di PT Fuji Seat Indonesia memberikan manfaat dalam keamanan, efisiensi manajemen, dan peningkatan produktivitas. Sebelum integrasi, proses bisnis terfragmentasi dan bergantung pada pelaporan manual, sementara setelah integrasi, terjadi transformasi signifikan dalam pengelolaan akses, pengurangan biaya dan waktu, serta peningkatan akurasi data. Dengan demikian, integrasi ini membawa dampak positif terhadap efisiensi dan produktivitas perusahaan
Le symbolisme phonétique et la fonction iconique de l’analogie
Authors:   Sorbonne Université, France - STIH (EA 4509), Monneret Philippe
Published: June 2024

La définition du symbolisme phonétique est fluctuante et parfois confuse. Après avoir montré l’intérêt grandissant, mais qui demeure marginal, pour ce type de phénomène linguistique, nous proposons une analyse critique de la typologie très fréquemment citée de Hinton, Nichols et Ohala (1994), puis du traitement de la question dans la perspective de l’iconicité et, enfin, dans une perspective analogique. Une définition du prototype du symbolisme phonétique est proposée comme analogie phonosémantique, une analogie qui présente trois caractéristiques : elle implique un élément phonique, elle est binaire et hétérogène.
Petite exploration d’une « géographie affective ». La fonction mythopoïétique du phonosymbolisme dans le Muu igala
Authors:   Romanisches Seminar - Universität Zürich (UZH), Picciuolo Andrea
Published: June 2024

On discutera dans cet article la thèse soutenue pour la première fois par Lévi-Strauss dans un essai intitulé « L’efficacité symbolique » (publié en 1949), concernant en particulier l’efficacité performative transmodale du Muu Igala, un chant rituel du peuple guna et, plus en général, la fonction perlocutoire du mythe. Deuxièmement, on présentera la glose, et en partie la réfutation de la thèse de Lévi-Strauss, formulées par l'un de ses élevés les plus célèbres, Carlo Severi ; cela nous aidera à introduire le thème de la fonction mythopoïétique du symbolisme phonique dans le Muu Igala, objet de cette contribution. Nous avons pris en compte ce chant, tout d’abord à travers le prisme des analyses de Lévi-Strauss et Severi, puis en abordant directement les structures phonologiques de la langue guna du point de vue sémiologique, c’est-à-dire du point de vue de l’analyse formelle, descriptive et qualitative des formes phoniques du texte en question (avec plusieurs précautions qu'on verra après) en vue de comprendre leur valeur significative en contexte. On formulera en conclusion notre hypothèse sémio-linguistiquement orientée qui a pour but de harmoniser, en quelque sorte, les thèses de Lévi-Strauss et Severi.
Introduction : Sound symbolism in the age of digital orality. A perspective on language beyond 'nature' and 'culture'
Authors: Nobile Luca
Published: June 2024

After recalling the main empirical evidence in favour of sound symbolism, this Introduction presents the contributions offered by the authors of this issue of Signifiances (Signifying). It then addresses some of the epistemological and metaphysical issues that a full integration of sound symbolism into language theory entails, particularly concerning the relationship between language and reality, and between nature and culture. Finally, it proposes to explain the centuries-old preference of scholars for the arbitrariness of the sign as an effect of the pre-eminent role that writing on paper has played in their pragmatic-cognitive experience of language up to the digital revolution.
Formes dynamiques. Le geste sculptural et le principe de la variation
Authors:   Université du Luxembourg, Luxembourg, Colas-Blaise Marion
Published: June 2024

Faisant dialoguer la phénoménologie avec la sémiotique, l’anthropologie et la théorie de l’instauration, cet article s’interroge sur le devenir et la dynamique des formes, captées soit dans leur succession, soit dans leur co-présence. L’analyse des dessins préparatoires de Tony Cragg permet de mettre en avant la trace, en relation avec l’expression ou expressivité et une logique non plus représentative, mais présentative. Il s’agit alors de distinguer des instances d’énonciation (participante, subjectale et subjective) personnelles ou impersonnelles, mais aussi de penser l’interaction avec des matériaux et de prendre en considération les déterminations par un environnement social et culturel (représentations doxiques, normativisations), entre réexpression « instituante » et invention de nouveaux possibles.
Qu’est-ce qu’un citoyen global ? La vision d’une sémiotique cognitive
Authors: Brandt Per Aage
Published: June 2024

Cet article propose un modèle réaliste stratifié en tant que cadre général et global pour une description du monde humain vécu, ainsi que de ses strates et domaines d’expérience. On tentera de montrer comment une étude psycho-sémiotique doit être directement associée à une étude éco-sémiotique, parce que l’esprit est lui-même façonné par le monde sémiotique avec lequel il a évolué. Éthique, esthétique et pensée critique doivent maintenant converger, à la lumière des menaces contemporaines, pour défendre la possibilité d’une humanité et d’un habitat globaux et planétaires.
"Il m’a bien parlé l’bonhomme mais j’ai pas compris c’qu’il m’a dit !"Approche anthropologique sémiotique des discours réflexifs sur le langage en milieu rural
Authors:   MoDyCo. Université Paris-Nanterre, France, Danos Félix
Published: June 2024

Partant d’un travail ethnographique réalisé dans le Sud-Est du département de l’Allier (Région Auvergne-Rhône-Alpes), cet article propose une application de certains concepts de l’anthropologie sémiotique nord américaine (Parmentier 1994, 2006). À travers l’analyse d’une interaction mettant en scène le discours des autres, il montrera l’importance de la prise en compte des processus donnant forme et sens à l’espace et au temps, nommés formulations chronotopiques (Agha 2015), pour comprendre la hiérarchisation des manières de parler dans les discours réflexifs sur le langage.
Sémiogenèse : premiers instants
Authors:   CNRS - Laboratoire Histoire de Théories Linguistiques, UMR 7597, Piotrowski David
Published: June 2024

Cet article s’intéresse au premier instant de la sémiogenèse, ce moment énigmatique où un fait simplement expressif se prépare à devenir signe. Il s’agit d’un processus de polarisation où une expression, en laquelle le sens et le sensible sont d’un seul tenant, i.e. mutuellement indiscernables, se polarise pout faire apparaître les faces interdépendantes d’un signifiant et d’un signifié. Pour conduire cette étude nous aurons recours aux conceptions de Merleau-Ponty sur (i) l’élaboration du fait expressif, et (ii) la genèse de la première parole, soit comme recoupements et convergence de gestes verbaux, soit comme somme d’actes différenciateurs.
Introduction
Authors:   DISUM (Dipartimento di Scienze Umanistiche) — University of Catania, Italy, Bondi Antonino
Published: June 2024

In thisissue of Signifiances (Signifying)we will focus on a theoretical and dynamic point of view on the linguistic and semiotic dimensions at work in the constitution of individual and collective experience. The aim is to investigate the hypothesis of constitutive compatibility between two fundamental characteristics of meaning, namely its perceptibility and its sociality. These characteristics will be re-seized from the perspective of semiotic anthropology with a phenomenological, expressivist, and morphodynamic vocation. It is a perspective that is interested, at first sight, in the formation of the planes of expression which mediate the inscription and engagement of the subjects within social life. Thus, the various contributions will discuss a theoretical framework that encompasses what is called semiogenetic, which makes it possible to clarify the specific semiotic and semiolinguistic forms and issues that are imposed on the actors and constantly redirect their attention.
Robert Nicolaï, Parcours sémiotiques ou les mots des hommes. Une anthropologie langagière, Paris, L’Harmattan, collection « Du sens », 2019, 185 pages.
Authors:   LRL, Université Clermont Auvergne, Grégoire Michaël
Published: June 2024

COMPTE-RENDU de l'ouvrage : Robert Nicolaï, Parcours sémiotiques ou les mots des hommes. Une anthropologie langagière, Paris, L’Harmattan, collection « Du sens », 2019, 185 pages.
Biomechanics of the Patient with Bisphonate Osteonecrosis According to the Diagnosis Neurophysiological Monitoring
Authors:   Clinic of Endoscopic and Minimally Invasive Surgery (Stavropol State Medical University), Gabbasova Irina V. , Sletova Valeria A. ,   Pyatigorsk Medical and Pharmaceutical Institute, Loktionova Marina V. ,   I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), Naumov Stanislav S. ,   Clinic of Endoscopic and Minimally Invasive Surgery (Stavropol State Medical University), Oksentyuk Alina D. ,   I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), Ling Zhou ,   I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), Hui Tang ,   I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)
Published: June 2024

Effective rehabilitation of patients with volumetric jaw defects at the present stage of development of science and technology is impossible without a comprehensive analysis of biomechanical disorders and improvement of technical aspects of operational ways to eliminate them. The aim of the study was to analyze the biomechanical activity of the chewing muscles in patients with bisphosphonate osteonecrosis based on the results of neurophysiological monitoring. 184 patients with bisphosphonate osteonecrosis of the mandibular bone were monitored, 112 of whom were men and 72 women, group 1 included 60 % of patients who had an apparatus for extracellular osteosynthesis of jaw bones fixed, and group 2 – 40 % of patients whose jaw fragments were fixed with bone mini-plates of various profiles and cross-sections. In the preoperative period, all patients underwent general clinical studies, multispiral computed tomography, and monitoring of quality of life criteria using a modified questionnaire "The MOS 36-item Short-From Hervey". Results and discussion. Indicators in the long-term postoperative period in patients of group 1 approached the physiological norm on the healthy side and significantly improved on the affected side, compared with patients from group 2 who did not receive devices for extracellular osteosynthesis in the postoperative period. Conclusions. Ensuring the positioning of jaw bone fragments in three mutually perpendicular planes restores biomechanical balance in the dental and maxillary apparatus, which accelerates the rehabilitation of patients and predicts a favorable outcome of surgery.
Рrediction of Clinical Manifestations of Irritable Bowel Syndrome when Combined with Type 2 Diabetes Mellitus
Authors:   Central Clinical Hospital with Polyclinic, Suprun Oleg E. , Bagriy Andrey E. ,   M. Gorky Donetsk State Medical University Ministry of Health of the Russian Federation, Mikhailichenko Evgeniia S. ,   M. Gorky Donetsk State Medical University Ministry of Health of the Russian Federation, Andreeva Elena A. ,   Central Clinical Hospital with Polyclinic, Yevtushenko Alexandra A. ,   M. Gorky Donetsk State Medical University Ministry of Health of the Russian Federation, Suprun Evgeniy V. ,   Central Clinical Hospital with Polyclinic
Published: June 2024

The comorbidity of type 2 diabetes mellitus (DM) and irritable bowel syndrome (IBS) remain insufficiently studied. The aim of this study was to compare the clinical, laboratory and instrumental characteristics of patients with combination of IBS and type 2 DM with the clinical data of IBS and to develop criteria for predicting clinical manifestations of IBS in combination with type 2 DM on this basis. 107 patients with type 2 DM which have clinical manifestations of IBS were under observation. All patients were assessed for medical history and underwent a standard examinations. In addition, the levels of glycated hemoglobin, fructosamine, C-peptide, insulin, glucagon-like peptide-1 were assessed, the HOMA-IR and HOMA-B indices were calculated. As a result of the study, a number of statistically significant relationships between some clinical, laboratory and instrumental characteristics of patients and features of the clinical picture of IBS were identified. Based on the analysis of the data obtained, criteria for predicting the development of severe constipation syndrome, severe diarrhea syndrome and severe abdominal pain in patients with IBS and DM type 2 have been developed.
Features of Hygienic Care for Removable Prostheses Made of Thermoplasts
Authors:   Private Institution Educational Organization of Higher Education «Reaviz Medical University», Bizyaev Aleksey A. , Konnov Valery V. ,   V.I. Razumovsky Saratov State Medical University Ministry of Health of Russia, Pospelov Andrey N. ,   V.I. Razumovsky Saratov State Medical University Ministry of Health of Russia, Krechetov Sergey A. ,   V.I. Razumovsky Saratov State Medical University Ministry of Health of Russia, Maslennikov Dmitry N. ,   V.I. Razumovsky Saratov State Medical University Ministry of Health of Russia, Proshin Alexey G. ,   Private Institution Educational Organization of Higher Education «Reaviz Medical University»
Published: June 2024

As a result of the study, 74 patients with a diagnosis of dentition defects were made partial removable lamellar dentures from various structural dental materials. To identify the awareness of patients about the peculiarities of hygienic care for the oral cavity when using removable dentures, a preliminary survey of all respondents was conducted. The results of this survey demonstrated a low level of patient awareness of the specifics of hygienic procedures for the care of dentures. More than half of the respondents (52.4 %) did not have sufficient information about the rules and features of hygienic oral care when using removable orthopedic structures. Only 31 % of respondents cleaned removable dentures twice a day, more than half, 60 % cleaned the denture once a day. According to the results of the survey, 76.5 % of respondents revealed violations of the rules of personal oral hygiene. Additional hygiene products for the care of removable dentures in the form of cleaning tablets are used by 5.6 % of patients, 83.1 % of patients did not use additional hygiene products.
Dental Rehabilitation of Patients with Oncological Diseases of the Maxillofacial Region Using Dental Mini-Implants
Authors:   Far Eastern Federal University, Balan Vyacheslav A. , Rusakova Elena Y. ,   Far Eastern Federal University, Lyakh Elena V. ,   Far Eastern Federal University, Bukov Denis O. ,   Far Eastern Federal University, Chependyuk Tatyana A. ,   Far Eastern Federal University
Published: June 2024

The traditional method of dental rehabilitation of Malignant diseases of the oral mucosa and maxillofacial region is the use of a removable plate prosthesis. The disadvantage of this prothesis is a significant volume, insufficient fixation and mobility, which leads to problems with speech function and taste sensitivity. As an alternative, rehabilitation of patients by prosthetics based on dental mini-implants was proposed, which allows implantation in the alveolar process of patients with adverse histomorphological changes in the alveolar bone after radiation exposure. The aim of the study is to analyze the effectiveness of dental rehabilitation of patients with acute respiratory infections using dental mini-implants. According to the results of the study, the average values of periotestometry ranged from –0.3 to 0.6 cu (p < 0,002), the average level of interleukin-6 (IL-6) from 0.18 ± 0.23 to 3.8 ± 1.1 pg/ml, while in the postoperative period – from 4.45 ± 0.22 to 5.5 ± 1.1 pg/ml. (p < 0,002), the average value of quality of life (OHIP-14) is 14 ± 1.2 points (p < 0,004). The use of mini-implantation is the optimal method of restoring the function of chewing and aesthetics in patients who have suffered from cancer, within the permissible radiation dose (no more than 70 gy).
Features of Oral Cavity Treatment for Acute Respiratory Viral Infections
Authors:   Social dentistry of Belogorye «Dental clinic of Stary Oskol urban district», Gontarev Sergey N. ,   Belgorod State National Research University, Gontareva Inna S. ,   Social dentistry of Belogorye «Dental clinic of Stary Oskol urban district»,   Belgorod State National Research University, Furda Nadezhda I. ,   ANO "Association "Dentistry", Punko Daria S. ,   Belgorod State National Research University,   Medical center "Family Doctor", Stepanova Alina I. ,   Belgorod State National Research University,   Dental clinic "Karat", Yassin Mustafa ,   Belgorod State National Research University,   Yakovlevskaya Central District Hospital
Published: June 2024

Acute respiratory viral infections (ARVI), particularly coronavirus disease (COVID-19), have become a global health concern. As a result, we examined the pathological processes in the oral cavity associated with ARVI. In acute respiratory viral infections, viral damage to the epithelium, swelling and redness in the soft palate, hypersecretion of glands, looseness and granularity of the oral mucosa are noted. Inadequate treatment of ARVI, as well as deterioration of the general condition of the body, leads to the development of many diseases of the oral cavity. Our task was to find alternative treatment methods that cause a minimum of side effects on the body, have low toxicity, do not cause allergic reactions, are well tolerated by patients of all ages, and also have the maximum positive effect. An undoubted alternative to antibacterial agents is herbal remedies. For this purpose, modern literature included in Scopus, Web of Science, RSCI, Google Scholar was studied.
Kemiskinan, Tingkat Pendidikan, dan Sikap Moderat Dalam Beragama: Studi Kasus Masyarakat Gunung Kidul, Daerah Istimewa Yogyakarta
Authors: Qoyum Abdul , Munir Misbahul , Munawaroh Uum
Published: June 2024

Kemiskinan dan pendidikan merupakan dua hal penting yang dianggap memiliki pengaruh terhadap cara pandang dan sikap seseorang dalam hubungan sosial keagamaan. Penelitian ini bertujuan untuk mengetahui bagaimana pengaruh tingkat kemiskinan dan Pendidikan terhadap sikap moderat dalam beragama seseorang. Penelitian menggunakan sampel 390 responden yang berasal dari 114 kelurahan di Kabupaten Gunung Kidul, dengan menggunakan kuesioner. Berdasarkan pada pengujian statistic, penelitian ini membuktikan bahwa terdapat hubungan negatif antara faktor kemiskinan dengan sikap moderat seseorang dalam beragama. Artinya, semakin tinggi tingkat kemiskinan, maka akan semakin rendah sikap moderasi beragama seseorang. Selanjutnya, penelitian ini juga membuktikan bahwa faktor Pendidikan tidak berpengaruh secara signifikan terhadap sikap moderat. Oleh karena itu pemerintah perlu memperhatikan faktor kemiskinan untuk memperbaiki sikap moderat dalam beragama suatu masyarakat.
Struktur Ekonomi Pancasila (Pancasilanomics)
Authors: Budimanta Arif
Published: June 2024

Sistem Ekonomi Pancasila dibangun untuk menentukan arah dan pedoman bagi perekonomian Indonesia. Sistem Ekonomi Pancasila digali dari nilai-nilai luhur bangsa dan pemikiran yang dikembangkan oleh para pendiri bangsa, sehingga penerapan Sistem Ekonomi Pancasila akan memperkuat tata nilai dan budaya Indonesia dalam mencapai tujuan bersama, yakni keadilan dan kemakmuran. Sistem Ekonomi Pancasila lebih mengutamakan keseimbangan sosial, bukan keseimbangan pasar. Dengan corak Ekonomi Pancasila yang tidak anti pasar, negara menerima kondisi persaingan pasar selama dalam koridor adil dan sehat. Gagal memahami dan membedakanpengelolaan ekonomi berdasarkan Pancasila dan pasar bebas akan melahirkan suatu kebijakan yang saling bertabrakan satu dengan yang lain. Hasilnya, pemerataan hasil pembangunan tidak akan pernah terwujud.
A gene signature to predict the survival of patients with multiple myeloma
Authors:   Department of Respiratory and Critical Care Medicine, Affiliated Hospital of North Sichuan Medical College, No. 1 the South of Maoyuan Road, Nanchong, Sichuan 37000, PR China., Cao Dan , Liu Huan ,   Center of Infectious Diseases, West China Hospital of Sichuan University, Chengdu 610041, China.
Published: June 2024

Background: Multiple Myeloma (MM) is an incurable hematological malignancy. Genomic studies have provided solid foundation for understanding the molecular mechanisms underlying progression of multiple myeloma. This study aimed to identify novel molecular markers associated with MM prognosis. Methods: The GSE136337 dataset was downloaded from GEO database and taken as the training cohort. The GSE24080 and GSE57317 datasets also obtained from GEO database and were set as the external validation cohorts. In training cohort, Kaplan–Meier analysis and univariate Cox regression analyses were performed to preliminary identify prognostic genes. Multivariate Cox regression analysis was applied to build prognostic signature, which was then verified in the validation cohorts through Kaplan–Meier, Cox, and ROC analyses. Gene Set Enrichment Analysis (GSEA) and tumor immunity analysis were used to elucidate the molecular mechanisms and immune relevance. The half-maximal inhibitory concentration (IC50) of chemotherapeutic drugs in MM patients were estimated by pRRophetic algorithm. Results: A total of fifteen genes were individually associated with overall survival via Kaplan–Meier analysis and univariate Cox regression analyses. A novel five-gene signature (CTPS1, FABP5, STK26, HECA and TMEM167B) was constructed for MM prognosis prediction. The ROC curve showed that the prognostic signature performed well at predicting overall survival in both the training cohort and the external validation cohorts. The K-M curve revealed low risk group had significantly higher survival rates compared with the high risk group. This signature was further proven to be an independent prognostic factor compared to other clinic-pathological parameters via the multivariate Cox regression analysis. Gene set enrichment analysis revealed the pathways enriched in the high risk group were mainly associated with the cell proliferation and glycolysis. Tumor-infiltrating cells had notably differential levels of expression between high and low risk groups. Moreover, the patients in the high risk group were more sensitive to chemotherapy. Conclusions: The five-gene signature could accurately predict patients’ prognosis and had close relationship with the tumor immune microenvironment and drug sensitivity, which may provide new insights for prognosis and treatment of MM patients and help doctors make more rational treatment decisions.
Gastrointestinal bleeding caused by a hidden gastrointestinal stromal tumor of the stomach
Authors:   Department of Gastroenterology, Luigi Sacco Hospital, University of Milan, Milan, Italy, Toppeta Angelica , Molteni Paola ,   Department of Gastroenterology, Luigi Sacco Hospital, University of Milan, Milan, Italy, DellEra Alessandra ,   Department of Gastroenterology, Luigi Sacco Hospital, University of Milan, Milan, Italy, Ardizzone Sandro ,   Department of Gastroenterology, Luigi Sacco Hospital, University of Milan, Milan, Italy
Published: June 2024

Gastrointestinal stromal tumors (GISTs) are the most common type of mesenchymal tumor of the gastrointestinal tract. This report presents a case of a large exophytic stomach GIST that was not visible at esophagogastroduodenoscopy (EGD). A 70-year-old female presented to the emergency room with presyncopal symptoms and a history of several episodes of melena. Blood tests revealed severe anemia. She underwent an EGD, which yielded negative results. Subsequently, she was hospitalized and scheduled for ileo-colonscopy and videocapsule enteroscopy (VCE). Abdominal ultrasound showed the presence of a mass in the epigastric region near the liver. Computed tomography (CT) scans confirmed the presence of a mass in the gastric wall that, at endoscopic ultrasound (EUS) exam and biopsy, was diagnosed as a tumor that originated from the muscular layer of the stomach. Surgery was performed to excise the tumor, and the diagnosis of GIST was confirmed by histomorphological and immunohistochemical findings. According to the postoperative assessment, the tumor was classified as high risk, for which the recommended treatment is imatinib.
Risk factors of supplementary suckling technique in infants less than 6 months of age with severe acute malnutrition in Yemen and Sudan
Authors:   Faculty of Medicine and Health Sciences, University of Aden, Yemen., Baazab Mohamed Salem Mohamed , Bilal Jalal Ali ,   Pediatrics Department, College of Medicine, University of Shaqra, KSA., Ba-Saddik Iman Ali ,   Faculty of Medicine and Health Sciences, University of Aden, Yemen., Arabi Ali Mohammed ,   Faculty of Medicine, University of Khartoum, Sudan.
Published: June 2024

Objectives: Supplementary suckling technique (SST) can support and sustain nutritional rehabilitation for catch-up growth. The main aim of this study was to identify the associated risk factors of supplementary suckling technique in infants less than 6 months of age with SAM in Yemen and Sudan. Methods: This was a prospective hospital-based study among infants less than 6 months of age with SAM who were exposed to supplementary suckling technique, following breastfeeding failure. The study was conducted between January 2018 through December 2020 in both domains.
Perinephric and psoas abscesses leading to empyema: An unusual tuberculosis presentation
Authors:   Department of Radiology, Northern Mindanao Medical Center, Philippines., Luke D Yap Justin , L Aspirin Justin Nico ,   Department of Radiology, Northern Mindanao Medical Center, Philippines.
Published: June 2024

Tuberculous psoas abscess usually results from tuberculous spondylitis but may also develop from direct spread or via hematogenous route [1]. Our case involves direct spread from an adjacent perinephric abscess with associated thoracic extension from suspected direct erosion or a diaphragmatic defect. We present a case of pleural empyema arising from abdominal tuberculous abscesses. This is an 11-year-old male who initially presented with a three-week history of cough, intermittent fever, and dyspnea. Congenital diaphragmatic hernia was first suspected at the emergency department when an opacified left hemithorax with cystic lucencies was noted. Further imaging of the chest and upper abdomen was done in our institution revealing large left perinephric and psoas abscesses with intra-thoracic extension resulting in empyema thoracis and necessitans. Culture of the abscess fluid yielded no growth but GenExpert tested positive for M. tuberculosis. Tuberculosis remains a major illness in developing countries and has a multitude of infection sites and clinical presentation. Our case presented as an ascending thoracic extension of a perinephric and psoas abscess, likely from a diaphragmatic defect. The absence of spinal involvement proves its renal origin. The importance of CT scan is highlighted in medically-confounding cases such as this one.
KRAS p.G12C mutation in metastatic colorectal cancer
Authors:   Oncology Unit C.D.C Macchiarella – Palermo, Italy., Colombo Alfredo , Porretto Concetta Maria ,   Oncology Unit C.D.C Macchiarella – Palermo, Italy.
Published: June 2024

Tumors often have KRAS mutations. It occurs in around 30% of all cancer cases and almost 50% of metastatic colorectal cancer cases, a leading cause of cancer-related deaths globally. KRAS mutations plays a significant role in CRC progression, as recent advancements in CRC biology and genetics have revealed. KRAS gene encodes a GTPase that regulates growth factor and receptor signal pathways. KRAS mutations commonly occur in codons 12 and 13, possessing oncogenic characteristics. Abnormal KRAS activation boosts cancer-associated signals in CRC, including cell growth, movement, and new blood vessel formation. We examine the prognostic implications of KRAS mutations in this review. The KRAS p.G12C mutation is linked to a poorer prognosis in metastatic CRC. Mutations in amino acids at the same position in a protein can unexpectedly contribute to cancer due to the interplay of structure and conformation. Additionally, we provide a summary of the clinical evidence for the efficacy of novel inhibitors in targeting KRAS p.G12C as a potential treatment for metastatic CRC.
Cardiac angiosarcoma: Clinical image
Authors:   Unit of Internal Medicine, AO Santa Maria Terni, Italy., Sanesi Leandro
Published: June 2024

A 45-year-old male patient was admitted to hospital for a reported episode of tachycardia and chest pain followed by loss of consciousness. History of COPD in active smoking, drug abuse. Upon admission, a brain CT scan was performed resulting negative and a chest x-ray showed the presence of bilateral basal micronodules, for which a chest CT scan with contrast medium was performed. This examination showed “gross endoluminal thrombotic protrusion originating from the lateral wall of the right atrium with nonhomogenous peripheral impregnation of the contrast medium infiltrating the myocardium and adjacent pericardium” as well as multiple pulmonary nodular lesions with random distribution, angiocentric.
Laparoscopic treatment of adult diaphragmatic hernia after minimally invasive hepatectomy: A case report and literature review
Authors:   Unit of Digestive, Endocrine and General Surgery, Department of Surgery, Université Catholique de Louvain, CHU UCL Namur (Site Godinne), B-5530 Yvoir, Belgium., Kuzmova Miroslava , Goussens Alexandre ,   Unit of Digestive, Endocrine and General Surgery, Department of Surgery, Université Catholique de Louvain, CHU UCL Namur (Site Godinne), B-5530 Yvoir, Belgium., Dili Alexandra ,   Unit of Digestive, Endocrine and General Surgery, Department of Surgery, Université Catholique de Louvain, CHU UCL Namur (Site Godinne), B-5530 Yvoir, Belgium., Bertrand Claude ,   Unit of Digestive, Endocrine and General Surgery, Department of Surgery, Université Catholique de Louvain, CHU UCL Namur (Site Godinne), B-5530 Yvoir, Belgium.
Published: June 2024

Introduction: History of surgery is the second most common cause of acquired diaphragmatic hernia (DH) after trauma. Herein, we present a case of diaphragmatic hernia following minimally invasive laparoscopic liver surgery. We also reviewed the literature on adult DH after hepatectomy, the primary surgical cause. Methods: Clinical case presentation and systematic literature review of adult DH after hepatectomy. Results: A 71-year-old male patient was diagnosed a DH 42 months after a right extended laparoscopic hepatectomy for alveolar echinococcosis. A minimal invasive approach permitted a primary suture with intraperitoneal onlay mesh. There is no sign of recurrence at the 19-months follow-up.
Be alert to aspiration in elderly bedridden patient
Authors:   Department of Cardiology, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Youdian Road No. 54, Hangzhou, Zhejiang Province, China., Bingxu Chen , Jie Shi ,   Department of Cardiology, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Youdian Road No. 54, Hangzhou, Zhejiang Province, China., Yuangang Qiu ,   Department of Cardiology, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Youdian Road No. 54, Hangzhou, Zhejiang Province, China., Zhenyu Ju ,   Department of Cardiology, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Youdian Road No. 54, Hangzhou, Zhejiang Province, China., Jie Chen ,   Department of Cardiology, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Youdian Road No. 54, Hangzhou, Zhejiang Province, China.
Published: June 2024

Aspiration is one common complication during medical service practice, and could also incur severe outcome in elderly patient. We had three patients experienced this kind of accidence unfortunately last month, and only one survived at last. Hence, we advised physicians should be more alert to this complication, especially for elderly patients with some illness, and perform the deglutition training program regularly in case.
Concurrent diagnosis of severe haemophilia A and acute lymphoblastic leukemia in a child: First report in Greece
Authors:   Children’s & Adolescent’s Hematology-Oncology Unit of 2nd Pediatric Department, School of Medicine, Aristotle University of Thessaloniki, AHEPA University General Hospital of Thessaloniki, Greece., Palabougiouki Maria
Published: June 2024

Haemophilia A is a congenital bleeding disorder resulting by deficiency of coagulation factor VIII and Acute Lymphoblastic Leukemia (ALL) Is the most common cancer type in children. The concurrence of hemophilia and ALL in pediatric patients is quite rare. We report a case of a 2.5 year old boy, with an uneventful past history, which presented with pallor, petechiae, ecchymoses and lethargy to the emergency department. A full blood count on admission revealed severe leukocytosis, anemia and thrombocytopenia. Diagnosis of ALL was confirmed and the patient was put on chemotherapy. Excessive bleeding from the site of entry of the central venous catheter led to complementary testing, which revealed very low levels of Factor VIII and severe Haemophilia A was also diagnosed. The patient suffered from minor gastrointestinal bleeds and a severe intrabdominal hemorrhage due to an abcess eruption during his treatment for ALL. To date, very few cases of ALL and Haemophilia have been reported in children, and due to this rarity there are no guidelines concerning the adjustments in treatment in this small population of patients.
Brain Derived Neurotrophin Factor (BDNF) as a clinical marker of endometriosis
Authors:   Hospital García Orcoyen, General hospital in Estella-Lizarra, Spain., Manero Manuel Garcia , Goyenechea Nicholas Garcia ,   Faculty of Medicine. University of Navarra, Spain.
Published: June 2024

Background: Endometriosis is a chronic, multifactorial disease of unknown etiology that affects approximately 10% of all women of childbearing age. It is characterized by dysmenorrhea and chronic pelvic pain, often associated with other symptoms (dyspareunia, dyschezia, rectal bleeding, dysuria, among others) and in 30-40% of cases it is associated with infertility. The presence of pelvic pain is related to the process of neuroangiogenesis, with the presence of BDNF being a key piece in its development. Several recent studies have shown that BDNF levels are elevated in the serum of patients with endometriosis compared to patients without endometriosis. The objective of this study is to demonstrate if BDNF levels are higher in patients with endometriosis and if there is am correlation with the level of pain. Material and methods: The study included 59 patients diagnosed with ovarian endometriosis in the Gynecology service of the Garcia Orcoyen Hospital during the period from November 2021 to August 2022. A blood sample was taken before surgery and their BDNF blood levels were determined. The levels of BDNF were analyzed compared to the control group in 10 patients undergoing laparoscopic tubal ligation to establish if the levels were higher in the endometriosis group and if there was a correlation with the intensity of pain.
Cutaneous lesions, polyuria, polydipsia, and adenopathies in a pediatric patient
Authors:   Department of Dermatology, Hospital Universitario Sant Juan, Alicante, Spain., Sirvent Lucía García
Published: June 2024

This abstract presents a case of multisystemic Langerhans cell histiocytosis (LCH) in a 3-year-old boy with diverse clinical manifestations, including language delay, recurrent acute otitis media, pruritic scalp plaques, and erythematous trunk papules. Laboratory and radiological findings supported the diagnosis, which was confirmed by histopathological analysis and immunohistochemical markers. The case underscores the importance of recognizing skin involvement as an initial presentation and highlights evolving therapeutic strategies, including targeted inhibitors, for improved LCH management.
The relationship between thyroid and cancer (focus on breast cancer)
Authors:   Faculty of Medicine, University of Lisbon, Portugal., Costa Marta , Greiger Maria Carmo ,   Faculty of Medicine, University of Lisbon, Portugal.
Published: June 2024

The function of the thyroid gland is very important for metabolic processes including basal metabolic rate, nervous reflexes, temperature regulation, cardiac contractility, intestinal transit and growth and maturation processes of tissues and organs [1]. Therefore, the thyroid affects the function of virtually all organs and systems. Thyroid hormones (THs) called tetraiodothyronine (thyroxine or T4) and triiodothyronine (T3) and a thyroid-stimulating hormone or thyrotropin (THS), play a role in growth, development and metabolism. In adults, diseases commonly associated with the thyroid are caused by excess or lack of THs (hyper or hypothyroidism respectively). However, thyroid hormones and their receptors may play a role in the development and progression of other diseases, namely in the promotion and suppression of tumors [1].
Successful use of doxycycline as sclerosing agent with wound vac to treat chronic groin seroma: A case study
Authors:   Cleveland Clinic Plastic Surgery Department, Cleveland, Ohio, USA., Kelley Rebecca , Padubidri Arvind ,   Cleveland Clinic Plastic Surgery Department, Cleveland, Ohio, USA.
Published: June 2024

Introduction: Seromas are one of the common post operative complications that surgeons must manage. There are several modalities that surgeons utilize to treat this problem including both operative and nonoperative strategies. This case report describes utilizing KCI Veraflo wound vac with doxycycline sclerotherapy to treat a chronic groin seroma.