bluuebunny/crossref_metadata_2025 huggingface dataset:
The Influence of Historical Events on Victorian Literature
Authors: Nuri Alaviyya
Published: December 2024

Victorian literature serves as a rich reflection of the 19th century’s transformative historical events, including the Industrial Revolution, the expansion of the British Empire, social reform movements, and challenges to traditional religious beliefs. This article explores how authors such as Charles Dickens, Elizabeth Gaskell, Rudyard Kipling, Charlotte Brontë, Thomas Hardy, Alfred Lord Tennyson, and Matthew Arnold addressed themes of industrialization, colonialism, class conflict, and spiritual doubt. Through their works, Victorian writers critiqued societal norms, highlighted inequalities, and grappled with the shifting moral and intellectual landscape of their time. Their literature remains a vital lens through which to understand the complexities of the era and its enduring relevance today.
DA RESPONSABILIDADE CIVIL E O DIREITO DO CONSUMIDOR FACE A GESTÃO DE ESTACIONAMENTOS
Authors: Silva Junior Paulo Roberto Costa da
Published: December 2024

This study addresses the issue of civil liability and consumer rights in the context of parking management. The objective is to analyze the legal and legal aspects involved in the provision of parking services, considering the rights and duties of the parties involved. The responsibilities of establishments offering parking services, the obligations of consumers and the legal consequences in the event of damage or incidents occurring during the parking period will be discussed. The methodology adopted in this study is based on bibliographic research and jurisprudence analysis. Legal sources will be consulted, such as laws, codes, doctrines, scientific articles and court decisions, in order to base the discussion on civil liability and consumer rights in parking services. Concrete cases that generated legal controversies will also be examined, in order to understand how the courts have interpreted the existing legislation. The discussion will be guided by the analysis of the legal elements involved in the relationship between parking establishments and consumers. In addition, specific laws and regulations governing the provision of parking services will be presented, as well as relevant legal cases that brought new understandings to the matter. The discussion will seek to provide a comprehensive and up-to-date view of civil liability and consumer rights in parking lot management, contributing to a clearer understanding of the rights and duties of the parties involved in this legal relationship.
USO DA ISOTRETINOÍNA NO TRATAMENTO DE ACNE GRAU III: ABORDAGEM SOBRE RISCOS E BENEFÍCIOS.
Authors: Araújo Regina Castro , Brito Danielle de Souza , Santos Vitoria Bispo dos
Published: December 2024

Isotretinoin is a medication for the treatment of grade III acne vulgaris used orally that requires a special prescription. It acts to reduce the production of sebaceous gland secretions, reduce the size of the glands and their activity and also restrict the growth of acne. Despite being highly effective in its use, the medicine also has major adverse effects that can be harmful to the user and for this reason requires medical supervision.The objective of the study was to succinctly show the risks and benefits of using the drug. The research was constructed based on bibliographic reviews with quick searches of articles from the last 5 years that covered the topic in a broad way that clarified doubts.In-depth studies of the profiles of patients undergoing treatment with isotretinoin provides extremely important findings on the diversity of this population group. Investigating these profiles can reveal whether certain age groups or subtypes of acne respond differently to isotretinoin. It was found that the use of Isotretinoin is essential in the treatment of grade III acne, emphasizing the practice of a personalized approach due to the needs of each patient, highlighting its benefits and warning about its risks, especially in women of childbearing age.
LAR, DOCE LAR: LEVANTAMENTO DE DADOS SOBRE O IMPACTO DO AMBIENTE DOMÉSTICO EM FELINOS ACOMETIDOS PELA SÍNDROME DE PANDORA
Authors: Silva Bianca Lucindo Neves da , Góes Paula
Published: December 2024

Pandora Syndrome in domestic felines is a complex and multifactorial condition that has been gaining increasing attention due to its diagnostic and therapeutic challenges. This Feline Behavioral Disorder (FBD) presents a variety of clinical signs and lower urinary tract disturbances, significantly impacting the quality of life of affected animals. Understanding the genetic and environmental factors involved in the syndrome is essential for the development of effective therapeutic strategies. This study aims to conduct a data survey on the domestic management practices used by cat owners dealing with Pandora Syndrome. The goal is to identify and comprehend the need for information and map the knowledge gaps related to environmental management.
IMPACTOS DA LEI Nº 14.181/2021 NO TRATAMENTO E PREVENÇÃO DO CONSUMIDOR SUPERENDIVIDADO
Authors: Soares Filho Tancredo Castro , Amoedo Rafael Seixas de
Published: December 2024

Over-indebtedness is a reality that affects many Brazilian consumers, characterized by the inability to pay all debts without compromising the minimum necessary for subsistence. In response to this social issue, Law No. 14,181/2021, known as the "Over-Indebtedness Law," came into effect in July 2021. This research aims to analyze the impacts of this legislation on the treatment and prevention of over-indebtedness, focusing on its legal innovations, protection mechanisms, and preventive and corrective measures. Through a bibliographic and jurisprudential approach, the study reveals that the law promotes greater transparency in credit granting, encourages debt renegotiation, and reinforces the preservation of human dignity. The findings highlight significant contributions to sustainable financial inclusion and a reduction in new cases of over-indebtedness.
IMPACTO PSICOLÓGICO DO PROFISSIONAL DE ENFERMAGEM NA LINHA DE FRENTE DA COVID-19
Authors: Souza Luzimaria Pereira De , Pereira Valdirene da Silva , Duarte Adriana Suigh Carlos
Published: December 2024

A pandemia de COVID-19 impôs desafios sem precedentes aos enfermeiros, que se viram na linha de frente do combate ao vírus. Este estudo analisou as mudanças na atuação desses profissionais, os impactos psicológicos e as estratégias de enfrentamento. A revisão da literatura revelou que os enfermeiros enfrentaram aumento da carga de trabalho, desgaste físico e emocional, falta de conhecimento inicial sobre a doença e necessidade de rápida adaptação a novos protocolos. A pesquisa constatou altos índices de ansiedade, depressão e burnout entre os enfermeiros, evidenciando a necessidade de suporte psicológico contínuo. A escassez de EPIs adequados aumentou a vulnerabilidade à infecção, impactando a qualidade do cuidado. Apesar das dificuldades, os enfermeiros demonstraram resiliência e capacidade de adaptação, transformando a experiência em aprendizado. O estudo conclui que é crucial valorizar e proteger os enfermeiros, garantindo condições de trabalho seguras e suporte emocional. Medidas eficazes são essenciais para promover a resiliência desses profissionais e a qualidade da assistência durante crises de saúde pública.
USO DE POLIMETILMETACRILATO PARA FINS ESTÉTICOS EM PACIENTES NÃO IMUNODEPRIMIDO
Authors: Pereira Thiago Mattos , Araújo Synara Abrantes de
Published: December 2024

In a world where the importance of care through aesthetic methods predominates, addressing the plastic component (polymethylmethacrylate - acronym PMMA) is fundamental, because it allows the understanding of its composition, its forms of use, its effects, as well as denounces its maximum risk and prohibition to the aesthetic purpose, in addition to directing the appropriate treatment, when, even then, procedures with the product are performed by professionals who are not trained and qualified. Considering the methods of application of polymethylmethacrylate, the gel form for cutaneous filling of small areas of the body is one of the most used and required by qualified medical professional, with restricted dose of use of the product, with proper certification from the National Health Surveillance Agency, only for repair of skin or integumentary defects.
PROCESSOS PSICOTERAPÊUTICOS: SUAS CONTRIBUIÇÕES NA QUALIDADE DE VIDA DA PESSOA COM DEMÊNCIA E ALZHEIMER
Authors: Pascoal Bruna Pereira Barros , Stone Jacira Barreto da Silva , Silva Luciana de Farias , Govêa Silvana Lima , Silva Rômulo Terminelis da , Silva Maria Neidiane
Published: December 2024

This study aims to elucidate and collect data on: “Psychotherapeutic Processes: Their contributions to the quality of life of people with dementia and Alzheimer’s”. It is understood that Dementia represents a cognitive disorder that causes the gradual impoverishment of brain function, affecting the ability to judge, memory, language and other cognitive processes, occurring more frequently in elderly individuals and the prevalence of dementia doubles every five years. years from the age of 65, based on this context, this article aims to present how psychotherapeutic processes can alleviate symptoms and improve the quality of life of people with dementia and Alzheimer's. Aiming to understand the causes and development of dementia and Alzheimer's disease, identifying factors that contribute to the physical and psychological burden on family members and their caregivers. The investigation is based on the CBT approach, Cognitive Behavioral Therapy, which specifically expresses its therapeutic mechanisms of action. It also hears contributions from the TAC approach. Behavioral Analytical Therapy that made it possible to understand the patient in their context. Therefore, this study was guided by a bibliographical research methodology, exploratory in nature, with a qualitative, field and descriptive approach, hypothetical-deductive and non-experimental. I understand that this line of research and approach is the most viable for the study for now. Therefore, the results contextualized here can be considered satisfactory to those initially proposed in this psychotherapeutic study. There are still clearly several aspects and possibilities to be analyzed in future studies, and, therefore, in more depth.
DESAFIOS NO COMBATE AS BACTÉRIAS RESISTENTES NO TRATO URINÁRIO
Authors: Pereira Giulianna Luzia , Silva Antônio Miguel Arias E , Silva Angelo Gimenes Gaiotto E , Garcia Breno Clemente , Silva Caio Felipe Afonso , Manente Millene Gonzalez , Francesco Lucas Massa De , Torre Lucas Kawamoto Dela , Rodrigues Raissa Haddad , Gun Sabrina
Published: December 2024

Urinary tract infections (UTIs), particularly those caused by resistant bacteria, are an increasing challenge for public health, with significant implications for treatment and disease control. The rise of antimicrobial resistance has made these infections more difficult to treat, increasing the risks of severe complications such as sepsis and renal failure. This article reviews current strategies in managing resistant UTIs, focusing on alternative therapies such as rational antibiotic use, immunomodulatory treatments, and innovations in rapid diagnostics. Despite promising prospects, controlling these infections faces challenges, including the lack of effective new antibiotics, cross-resistance, and inconsistent implementation of prevention policies. Future perspectives emphasize the importance of multidisciplinary approaches, increased investment in research, and new technologies to improve the diagnosis and treatment of these infections, aiming to reduce the global burden of resistant UTIs.
EDUCAÇÃO E SUSTENTABILIDADE: ANÁLISE DE JOGOS RECICLÁVEIS E DE BAIXO CUSTO PARA O ENSINO DE MATEMÁTICA
Authors: Araujo Weslay Vieira de , Santos Daiamara de Santana , Araujo Kécia Silva , Freitas Antônio Aguiar , Santos Davi Ribeiro dos , Brito José Márcio Machado de , Pinheiro Diego da Silva
Published: December 2024

Neste artigo é apresentado o resultado de uma pesquisa que objetiva analisar jogos e materiais recicláveis utilizados no ensino de Matemática. Tratando-se de uma pesquisa bibliográfica, foram analisados alguns estudos, elaborados por autores de destaque para a temática, tais como: Grando (2000); Moura (1991); Rosada (2013), dentre outros. Ao término das análises, constatou-se que o jogo é um mecanismo importante para o ensino aprendizagem, esses dados revelam que os jogos e materiais manipuláveis ganham destaque cada vez maior no âmbito educacional. Outro ponto observado na pesquisa, é que a grande maioria desses jogos e materiais, pode ser desenvolvida de maneira reciclável, ou seja, de modo sustentável, através de papelão, garrafas, sucata e dentre outros recursos oriundos de matéria reciclável. Essa realidade é bem vista diante da atual sociedade, uma vez que, a repercussão em torno de problemas ambientais cresce cada dia mais. Os resultados apontam diversos materiais que podem ser desenvolvidos de maneira reciclável, mas, na realização desta pesquisa, foram analisados os recursos: Tangram; Jogo da Velha com Figuras Geométricas e o jogo Mankala Colhe Três.
Pelatihan Membangun Komunikasi Efektif untuk Meningkatkan Keterampilan Bernegosiasi bagi Pelaku Hubungan Industrial
Authors: Agusalim Lestari
Published: December 2024

Kemampuan komunikasi efektif antara pekerja dan pengusaha sering kali menjadi tantangan utama dalam hubungan industrial yang berdampak pada kinerja dan produktivitas organisasi. Pelatihan komunikasi efektif dapat menjadi solusi untuk meningkatkan keterampilan komunikasi, terutama dalam konteks negosiasi yang penting dalam menyelesaikan konflik dan membangun hubungan yang saling menguntungkan. Pengabdian ini menyoroti pentingnya komunikasi interpersonal dan nonverbal dalam hubungan industrial, serta bagaimana pelatihan yang melibatkan simulasi dan diskusi kelompok dapat meningkatkan pemahaman peserta tentang pentingnya komunikasi yang efektif. Pelatihan ini dilaksanakan oleh Direktorat Jenderal Pembinaan Hubungan Industrial dan Jaminan Sosial Tenaga Kerja Kementerian Ketenagakerjaan, dengan peserta dari berbagai kalangan, termasuk pengusaha, pekerja, serikat pekerja, serikat buruh, dan unsur pemerintah. Metode yang digunakan adalah ceramah interaktif yang memungkinkan peserta belajar secara kolaboratif dan mempraktikkan teknik komunikasi dalam situasi nyata. Evaluasi pelatihan dilakukan melalui pre-test dan post-test untuk mengukur peningkatan keterampilan, disertai uji beda, serta survei kepuasan peserta. Hasil menunjukkan adanya peningkatan signifikan dalam keterampilan komunikasi peserta, dengan nilai post-test lebih tinggi dibandingkan pre-test. Perbedaan ini menunjukkan bahwa pelatihan berjalan efektivitas. Selain itu, lebih dari 80 persen peserta menyatakan puas dengan pelatihan yang diberikan. Pelatihan ini tidak hanya meningkatkan kemampuan komunikasi, tetapi juga mempersiapkan peserta menghadapi tantangan hubungan industrial di masa mendatang dengan keterampilan yang diperlukan untuk menciptakan lingkungan kerja yang kolaboratif dan produktif.
Optimizing System Performance with Adaptive Algorithms for Signal Processing in Wireless Communication Networks
Authors: AISHAH Siti
Published: December 2024

In modern wireless communication networks, the need for high-speed, reliable, and efficient data transmission is paramount. Signal processing algorithms play a critical role in optimizing network performance, especially under dynamic conditions such as varying network loads and environmental interference. This paper presents an in-depth study of adaptive signal processing algorithms designed to improve the performance of wireless communication systems. We examine various techniques, including adaptive filtering, channel estimation, and interference cancellation, and assess their effectiveness in optimizing signal quality and network throughput. Through simulation and real-world case studies, the paper demonstrates how these algorithms can be applied to mitigate signal distortion and reduce data transmission errors in wireless networks. The results show that adaptive algorithms significantly enhance the overall system performance, particularly in environments with fluctuating signal conditions. The paper concludes with recommendations for further development in adaptive algorithms for future wireless communication standards, particularly 5G and beyond.
The Economics of Auto-Delivery: A Qualitative Exploration of Inventory Management and Profitability in Subscription Services
Authors: Permana Ngadi , Amelia Yessica , Rizal Muhammad
Published: December 2024

This qualitative literature review examines "The Economics of Auto-Delivery: A Qualitative Exploration of Inventory Management and Profitability in Subscription Services." Auto-delivery systems have gained traction in various industries, offering consumers convenience and suppliers a steady revenue stream. This study synthesizes existing literature to uncover the interplay between inventory management, profitability, and consumer behavior within auto-delivery frameworks. Key findings highlight the importance of advanced inventory strategies, dynamic pricing models, and the role of technology in enhancing operational efficiency. Additionally, the review discusses the implications of consumer behavior on subscription retention and the challenges suppliers face in minimizing churn. The insights derived from this review indicate that effective channel coordination and strategic investment in technology are essential for maximizing the profitability of auto-delivery services. However, the study acknowledges limitations such as the predominance of research in Western markets and the lack of empirical data to support theoretical insights. This review provides a comprehensive understanding of the economics surrounding auto-delivery systems, serving as a foundation for future research in this rapidly evolving domain.
Turning Down a Job Offer Professionally: Maintaining Positive Relationships for Future Opportunities
Authors: Westover Jonathan
Published: December 2024

This article provides research-backed guidance on how to effectively decline a job offer while preserving professional relationships and future opportunities. It emphasizes the importance of interpersonal skills like communication, relationship-building, and impression management when delivering challenging news. Drawing on theories of politeness, impression management, and organizational behavior research, the article outlines best practices: expressing sincere gratitude, offering a clear yet diplomatic explanation focused on personal fit rather than criticisms, and closing on a positive note that leaves the door open for future contact. By handling a job offer decline with finesse and consideration, candidates can turn down a role in a way that strengthens, rather than harms, professional connections. The article concludes that carefully declining an offer taps into broader leadership principles of cultivating talent through positivity, transparency and rapport, ultimately benefiting all involved parties over the long term.
Exploring the Scalability of 5G-Enabled E-Learning Platforms in Rural Areas
Authors: Apriyanto Apriyanto , Hossam Ahmed , Abed Yara , Anggara Reddy
Published: December 2024

Background. The rise of 5G technology offers the potential to revolutionize e-learning, particularly in rural areas where access to high-quality educational resources has historically been limited. Despite the promise of improved connectivity, the scalability and impact of 5G-enabled e-learning platforms in these regions remain underexplored.
Purpose. This study aims to assess the feasibility and scalability of implementing 5G-enabled e-learning platforms in rural areas and to evaluate their effectiveness in enhancing educational access and outcomes.  
Method. The research employs a mixed-method approach, combining quantitative analysis of internet connectivity, user engagement, and learning outcomes with qualitative interviews from educators and students. Data was collected from five rural regions across three countries where 5G infrastructure was recently introduced. The study measured improvements in e-learning adoption rates, student engagement, and academic performance over a 12-month period.
Results. Results indicate that 5G-enabled e-learning platforms significantly improved both access to education and student engagement, with a 30% increase in platform adoption and a 25% improvement in student performance. Educators also reported more dynamic and interactive learning experiences. However, challenges related to infrastructure costs and digital literacy were noted, which could limit scalability in certain regions.
Conclusion. In conclusion, the study demonstrates the potential of 5G technology to scale e-learning platforms in rural areas, improving educational access and outcomes. Nonetheless, addressing challenges such as infrastructure costs and digital literacy is critical for ensuring long-term scalability and success.
The Impact of Teachers’ Personality Competence and Students’ Attitudes on the Quality of Learning
Authors: Baidowi Ach. , Mokhtar Wan Khairul Aiman Wan , Haris Muhammad , Zada Mohd Ziaolhaq Qazi , Suteki Mega
Published: December 2024

Background. The quality of education in Indonesia is still stagnant, as evidenced by students’ achievements, which have not shown significant changes. This is influenced by the competence of teachers, who are not yet fully professional.
Purpose. This research aims to reveal the impact of teachers’ personality competence and students’ attitudes on the quality of learning, both partially and simultaneously.
Method. This study employs a quantitative method with a correlational approach, involving 57 students from SDN Pangilen 3 Sampang in grades 4, 5, and 6. The sampling technique used is saturated sampling. Data was collected through a questionnaire with a Likert scale ranging from strongly agree (5) to strongly disagree (1). Data processing includes descriptive statistical analysis, prerequisite tests such as normality and linearity, as well as validity and reliability testing. Hypothesis testing is conducted through multiple regression analysis, including simultaneous testing (F test) and partial testing (t test) to analyze the contributions between variables.
Results. It shows that teachers’ personality competence and students’ attitudes have a significant impact on the quality of learning, with Sig. values of 0.000 and 0.004, respectively. The simultaneous test confirms the collective influence of both variables, with teachers’ competence contributing 34.1% and students’ attitudes contributing 19.5%. The dominance of teachers’ competence in affecting the quality of learning is evident from its relative contribution of 63.6%.
Conclusion. This research emphasizes the importance of enhancing teachers’ personality competence to improve the quality of learning in schools.
Diversifikasi Pakan Alternatif Ternak Melalui Maggot di Desa Kadin, Kabupaten Bone
Authors: Aslinda Aslinda , Siraj Muhammad Luthfi , Heri Ririn Nurfaathirany , Gani Andika Wahyudi , Syarifuddin Syarifuddin
Published: December 2024

Kegiatan PKM yang dilaksanakan bagi masyarakat bertujuan menciptakan pengetahuan dan keterampilan dalam berwirausaha bagi masyarakat Tanete Riattang dalam mengembangkan usaha maggot sebagai salah satu bentuk usaha pakan alternatif yang efektif bagi peternak di Kabupaten Bone. Selain itu, tujuan dari dilaksanakannya kegiatan pelatihan ini ialah untuk menyelesaikan permasalahan ekonomi kreatif bagi masyarakat untuk menumbuhkan usaha baru pakan mandiri. Kegiatan pengabdian ini dilaksanakan dalam tiga tahap yaitu: (1) tahap perencanaan, (2) tahap pelaksanaan, (3) tahap evaluasi dengan jumlah peserta 45 orang. Hasil kegiatan pelatihan ini menunjukkan sebagian besar 80 persen dari jumlah 28 peserta telah memahami dengan baik konsep maggot serta mampu menerapkan pengeloaan maggot untuk menjadi pakan alternatif bagi peternak di Kabupaten Bone. Pelatihan PKM ini memberikan hasil dengan adanya 8 kepala rumah tangga membentuk 2 kelompok yang secara langsung membuat biofon awal sebanyak 3 tingkat sebagai rumah maggot, selain itu, kelompok tersebut juga dikolaborasikan dengan kelurahan setempat untuk diberikan bantuan modal sebesar satu juga untuk pembelian bibit maggot. Dari hasil kegiatan PKM ini dapat memberikan dampak positif sebagai awal penumbuhkan usaha mandiri yang dilakukan masyarakat setempat yang juga merupakan solusi alternatif terhadap para peternak di Kabupaten Bone untuk memperoleh maggot sebagai pakan alternatif dan murah.
El Estrés en el Rendimiento Académico de los Estudiantes de Primer Ingreso en la Universidad Especializada de Las Américas
Authors: Roy Delgado  , Agudo Quintín
Published: December 2024

El estrés académico afecta a los estudiantes en todas las etapas del proceso educativo, pero es especialmente crítico en aquellos de primer ingreso en instituciones universitarias. Este estudio se centró en analizar el nivel de estrés en los estudiantes de la Universidad Especializada de Las Américas, quienes, al enfrentarse a nuevas demandas académicas y sociales, experimentan niveles de estrés que impactan significativamente su rendimiento académico. A través de una encuesta realizada a 290 estudiantes, se identificaron las principales manifestaciones del estrés y sus causas asociadas. Los hallazgos destacan que la mayoría de los estudiantes experimentan dificultades relacionadas con la adaptación al nuevo entorno, la falta de estrategias de afrontamiento y la presión por cumplir con los estándares académicos. Con base en los resultados se propone un programa correctivo para el manejo del estrés, con el objetivo de reducir estos niveles y mejorar el rendimiento académico y la salud emocional de los estudiantes.
Deserción Escolar en la Carrera de Enfermería nivel Técnico de la Universidad Michoacana de San Nicolás de Hidalgo
Authors: Mata Jeronimo Laura , Escobar Gutierrez Edgar
Published: December 2024

En la escuela de enfermería nivel técnico de la Universidad Michoacana de San Nicolás de hidalgo se tiene una matrícula de 36 grupos divididos en los tres años de la carrera, con un total de 400 ingresos aproximadamente al primer semestre donde terminan la carrera 240 alumnos de forma promedio, si lo analizamos corresponde aproximadamente al 55 % de los alumnos que ingresan son los que se mantienen, por lo que se pretende con el siguiente trabajo analizar detenidamente la problemática existente para que los alumnos se mantengan en la carrera. Con el presente estudio se pretende analizar los factores determinantes que existen para la deserción escolar en la escuela de Enfermería y Salud Publica de la Universidad Michoacana de San Nicolás de Hidalgo., se tiene detectado que los alumnos ingresan a la escuela con edad promedio que va de los 18 a 45 años, recordando que es una carrera técnica y pueden ingresar a la facultad terminando secundaria , se analizaran factores que determinen la dificultad de continuar estudiando tomando en cuenta la edad , genero , motivación , elección adecuada de carrera, y otros compromisos existentes en caso de alumnos mayores casados y con hijos que por lo cual deben trabajar además de tratar de terminar la carrera.
Cloud Computing: Evolution, Challenges, and Future Prospects
Authors: Alzide Safana
Published: December 2024

Cloud computing has redefined how individuals and organizations interact with computational resources. Providing scalable, flexible, and cost-efficient solutions has become a cornerstone of digital transformation in various sectors, including healthcare, education, finance, and artificial Intelligence. This paper examines the evolution of cloud computing, its architecture, service delivery models, benefits, challenges, and emerging trends. It also highlights critical aspects of cloud adoption and the implications of recent technological advancements. The study utilizes authentic sources to offer a holistic view of cloud computing's current and future trajectory.
JISMONIY TARBIYA VA SPORT TASHKILOTLARIDA MEHNAT MUHOFAZASINI BOSHQARUV TIZIMINI SAMARADORLIGINING MATEMATIK MODELI
Authors:   Andijon mashinasozlik instituti, PhD, katta o‘qituvchisi, Andijon, O‘zbekiston, Latibov Shohruhbek Maxamatyusup o‘g‘li , Narziyev Shovkiddin Murtozayevich ,   PhD, dotsent, Renessans ta’lim universiteti, Toshkent, O‘zbekiston
Published: December 2024

Dunyo amaliyotida mehnat muhofazasini boshqaruv va tashkil etish tizimi samarali tizim sifatida tan olinayotgani va oʻz isbotini topgani bois, sportchilarning xavfsizligini taʼminlash, sport mashgʻulotlari turlarini hisobga olgan holda innovatsion qulay sharoitlar yaratish usullarini rivojlantirish hamda takomillashtirish boʻyicha ilmiy izlanishlar davlat tomonidan qoʻllab quvvatlanmoqda. Jismoniy tarbiya va sportda mehnat muhofazasini boshqaruv va tashkil etish tizimining sifatini sezilarli yaxshilash, xususan sportchilarning mehnat sharoitini yaxshilash va sport inventarlarining xavfsizligini optimallashtirish, mehnat xavfsizligini oshirish unumdorlikni aniqlash hamda mehnat jarayonida shikastlovchi omillarni kamaytirishga qaratilgan ilmiy tadqiqotlar olib borilmoqda. Ushbu maqolada, sportchilarning faoliyat xavfsizligini taʼminlovchi texnik vositalardan foydalanish samaradorligini oshirish va ularning asosiy parametrlarini optimallashtirish, mehnat muhofazasini boshqaruv va tashkil etish jarayonlarini modellashtirish boʻyicha tadqiqotlar ustuvor hisoblanmoqda. Shu bilan birga, mehnat muhofazasini boshqarish tizimi modeli, mehnatni muhofaza qilish unumdorligini hisoblash usuli hamda mehnatni muhofaza qilish tizimi samaradorligini aniqlash usuli dolzarb vazifalardan hisoblanmoqda.
JISMONIY TARBIYA VA SPORTDA JAROHATLANISHLARNING IQTISODIY ZARARNI ANIQLASH USLUBI
Authors: Sulaymanov Sunatilla Sulaymonovich , Narziyev Shovkiddin Murtozayevich , Latibov Shohruhbek Maxamatyusupo‘g‘li
Published: December 2024

Many injuries in sports are directly related to weak, competitive and poorly prepared joints of the musculoskeletal system, insufficient technical and tactical skills, that is, the effectiveness of the athlete training system. For the prevention of sports injuries, it is very important to develop a high level of ability to assess and regulate the dynamic and spatiotemporal parameters of spatial movements and voluntary muscle relaxant movements. Research has shown that 15 to 20 minutes of flexibility training per day can be very effective in preventing injury. In this article, the calculation of economic damage from injuries in physical culture and sports is considered using the method of mathematical and statistical processing. At the same time, important conditions for ensuring labor protection in the field of physical education and sports were studied.
Effect of PV Plants Connected to the Electrical Distribution System on the Mains Voltage
Authors: Aydın Hatice , Özcan Muciz
Published: December 2024

With the Paris Climate Agreement, incentives and demand for distributed generation are increasing day by day to reduce the carbon footprint, increase sustainability, and fight energy crises. However, since the current structure of the EDS is designed to be a one-way energy flow, the traditional grid evolves into a completely different structure with the connection to the distributed generation system. It is known that at the point where the distributed generation is connected to the system, it can have positive contributions to the grid as well as negative contributions. In this study, the effects of the generation-consumption relationship in the integration of PV power plants on the voltage on busbars, lines and transformers between the substation and the end user are investigated. Load flow analysis is performed with MatlabSimulink for two different generation-consumption cases and voltage variations are analyzed within the limits specified in the standards. The results of the analysis show that with the correct integration of PV plants, the grid voltage increases from 30.89 kV to 31.5 kV, which is the nominal voltage level, while with incorrect integration, it increased to 32.56 kV, an increase above the standards.
Challenges of knowledge management through lessons learned practices in construction industry: A North Cyprus perspective
Authors:   , Yalciner Hakan
Published: December 2024

With the increasing pressure for competitiveness on construction contractors, it is necessary to capture, transfer and reuse project knowledge and use lessons learned from previous projects to improve project performance. Knowledge is increasingly seen as a key but often underutilized asset. While Knowledge Management (KM) tends to focus on aspects of the capture, storing and retrieval of knowledge, knowledge creation, dissemination and application is also vital. Thus there is value in managing organizational knowledge. This knowledge originates from the experiences of organizations and is retained in the form of corporate memory. This retained knowledge is usable in expediting similar work in the future, thus benefiting the organization by assisting in rapid implementation on projects. The main objective of this thesis is to investigate the challenges of knowledge management (KM) and introduce a Model of Framework for Lessons Learned Process (LLP) that facilitates the sharing of knowledge about experiences and transferring of lessons learned at organizational level in North Cyprus construction industry. The research focus is to identify the processes of knowledge management, analyze the use of project feedback and lessons learned, and introduce a Model of Framework for LLP in construction contractors. A questionnaire survey, which was administered to the construction contractors in the industry, has been used in conducting the survey. The research includes an extensive literature study, interviews with managers on how to manage lessons learned processes throughout the organizations, analysis of this information to develop findings, and extending these to model an evolving framework of LLP over time in organizations. Without managing lessons learned process, the proper culture, and efficient technology application, the value of the knowledge, even if it is present, will be significantly less.
The path to grammaticalization of the phrase "taking into account": the specifics of lexical and semantic compatibility
Authors: Dai Xiahong
Published: December 2024

As a result of the constant process of grammaticalization, a large number of words have appeared in the Russian language that perform the function of prepositions. Modern linguists are paying more and more attention to such service words. The object is the word "considering" (phrase "taking into account"), which performs a function similar to the function of a preposition. The subject of the study is the semantics and syntagmatic properties of this word form. The purpose of the study is to identify the syntagmatic specifics of the phrase "taking into account". The task is to establish thematic groups of vocabulary, which occupies the positions of the left and right components of the structure, which is built using the phrase "taking into account". The author examines in detail the specifics of the lexical and semantic compatibility of the phrase "taking into account" and its grammaticalization stage. The source of the material is the National Corpus of the Russian Language. The results obtained can be applied in lexicographic practice. The study uses a descriptive method and a method of contextual analysis. As a result of the analysis of the material, several lexico-semantic groups with the highest frequency of occurrence in the left and right components of the structure were identified. It has been established that the following lexical and semantic groups are the most frequent in the position of the right component: verbal nouns denoting human action and activity; nouns denoting parameters; nouns naming various kinds of qualitative characteristics; nouns naming phenomena from the sphere of "finance". In the position of the left component, verbs or verbal nouns with the meaning of creative activity are most frequent; vocabulary denoting a change in state or quantity; verbs and verbal nouns with the meaning of doing something. The interrelationships between lexical and semantic groups in the position of the left and right components are revealed. This allowed us to conclude about the limited compatibility of the phrase "taking into account", which indicates the initial stage of grammaticalization. The novelty of the research lies in the fact that the work presents for the first time the results of a study of the specifics of the syntagmatics of the word form "taking into account".
Textological aspect of studying works on Yakut folklore in the context of studying materials of the Sibiryakov expedition (1894-1896)
Authors: Rufova Elena Stepanovna , Afanasyeva Alyona Andrianovna
Published: December 2024

This article is devoted to the study of works on Yakut folklore in the context of the materials of the Sibiryakov expedition (1894–1896). The relevance of the research lies in the study of the scientific works of I.A. Khudyakov "Verkhoyansky collection: Yakut tales, songs, riddles and proverbs, as well as Russian tales and songs recorded in the Verkhoyansky district by I.A. Khudyakov", E.K. Pekarsky "Samples of Yakut folk literature" in the textual aspect and directions of conceptual provisions regarding the folklore of the Sakha people. The purpose of the study is to reveal the textual parameters of the works of I.A. Khudyakov and E.K. Pekarsky as fundamental works on Yakut folklore, where the texts of the Yakut epic olonkho acquire particular significance. The methodological basis of the study is the theoretical directions of textual criticism as a branch of philology. The work uses cultural and hermeneutic methods in the comparative typological analysis of texts, sources, and documents. As a result of the study, the scientific context of the studies undertaken by I.A. Khudyakov and E.K. Pekarsky is emphasized, their personal contribution to Yakut folklore studies is highlighted, which confirms the importance of historical and literary contacts and contexts, but also convincingly reveals the role and significance of the Sibiryakov (Yakut region) expedition in the history of national culture as a whole.
Social Criticism and Biographical Literature: Nabokov's Early Exile Writings from the Perspective of Cultural Memory
Authors: Han Yue
Published: December 2024

This article examines Nabokov's works, analyzing the novels Mary, The Luzhin Defense, Despair, and The Gift, which he wrote in Europe during the early period of his emigration. Based on the literary activities of Nabokov's characters, the author explores aspects of biographical literature style. The main character expresses his personal attitude toward the surrounding reality through various forms of writing, such as autobiographies, biographies of others, diaries, poetry, and works considered “final pieces.” Through these forms, he conveys criticism of society, history, and reality. This literary activity covers a wide spectrum of Russian life in the past and symbols of Russian culture, which, like cultural memories, intertwine with the reality of life in emigration. The study applies close reading and comparative analysis methods, incorporating the theory of cultural memory as part of the research methodology. The novelty of this work lies in using literary creativity as a construction method to explain the critical attitude of characters and the author himself. Literary creativity is one of the main activities of the protagonists in Nabokov's early novels written in emigration and serves as an important channel for preserving Russian cultural memory. Nabokov skillfully uses literary techniques to convey his social critique and historical views, while simultaneously creating Russian narrative texts within the emigration context. This article examines the characters' literary activities in Nabokov’s novels as an object of study, allowing literature to be viewed as a field of cultural memory, as well as highlighting the generational context of biographical literature in the novels and its cultural connotation of memory. Through the "motifs" and genres in Nabokov's works, the “memory of genre” is explored, reflecting the socially critical attitude of both the main character and the author.
Synthesis and biological assessment of chalcone and pyrazoline derivatives as novel inhibitor for ELF3-MED23 interaction
Authors: Hwang Soo-Yeon , Jeon Kyung-Hwa , Lee Hwa-Jong , Moon Inhye , Jung Sehyun , Kim Seul-Ah , Jo Hyunji , Park Seojeong , Ahn Misun , Kwak Soo-Yeon , Na Younghwa , Kwon Youngjoo
Published: December 2024

HER2 overexpression significantly contributes to the aggressive nature and recurrent patterns observed in various solid tumors, notably gastric cancers. Trastuzumab, HER2-targeting monoclonal antibody drug, has shown considerable clinical success; however, readily emerging drug resistance emphasizes the pressing need for improved interventions in HER2-overexpressing cancers. To address this, we proposed targeting the protein-protein interaction (PPI) between ELF3 and MED23 as an alternative therapeutic approach to trastuzumab. In this study, we synthesized a total of 26 compounds consisting of 10 chalcones, 7 pyrazoline acetyl, and 9 pyrazoline propionyl derivatives, and evaluated their biological activity as potential ELF3-MED23 PPI inhibitors. Upon systematic analysis, candidate compound 10 was selected due to its potency in downregulating reporter gene activity of ERBB2 promoter confirmed by SEAP activity and its effect on HER2 protein and mRNA levels. Compound 10 effectively disrupted the binding interface between the ELF3 TAD domain and the 391–582 amino acid region of MED23, resulting in successful inhibition of the ELF3-MED23 PPI. This intervention led to a substantial reduction in HER2 levels and its downstream signals in the HER2-positive gastric cancer cell line. Subsequently, compound 10 induced significant apoptosis and anti-proliferative effects, demonstrating superior in vitro and in vivo anticancer activity overall. We found that the anticancer activity of compound 10 was not only restricted to trastuzumab-sensitive cases, but was also valid for trastuzumab-refractory clones. This suggests its potential as a viable therapeutic option for trastuzumab-resistant gastric cancers. In summary, compound 10 could be a novel alternative therapeutic strategy for HER2-overexpressing cancers, overcoming the limitations of trastuzumab.
Fluctuaciones en la respuesta inmune (actividad de fenoloxidasa) relacionadas con los ciclos circadianos y lunares en la anémona simbiótica Exaiptasia diaphana (Actinaria: Aiptasiidae)
Authors: Rodríguez-Jiménez Miel A , Rivera-Ortega Jacqueline , Thomé Patricia E
Published: December 2024

La capacidad inmune de los cnidarios les permite mantener la integridad de sus tejidos y prevenir infecciones ante amenazas de daño. Los cnidarios cuentan con un sistema inmune innato que incluye la melanina y enzimas, como la fenoloxidasa, que se activa en presencia de patógenos, generando compuestos reactivos y tóxicos para su eliminación. La anémona Exaiptasia diaphana es un organismo modelo en estudios sobre simbiosis, nutrición e inmunidad, ya que mantiene una simbiosis facultativa con las microalgas de la familia Symbiodiniaceae, como los corales; E. diaphana también puede existir en un estado aposimbiótico. Por tanto, E. diaphana es un modelo adecuado para estudiar el sistema inmune de los cnidarios. Para conocer la actividad inmune básica de esta anémona, nos preguntamos si existe variabilidad en la actividad de la enzima fenoloxidasa a lo largo del día, considerando 2 fases lunares (luna llena y luna nueva). Se tomaron muestras de mucus de 6 anémonas simbióticas y 6 aposimbióticas, previamente aclimatadas y mantenidas en cajas de 6 pozos con agua de mar filtrada bajo condiciones de luz natural. La actividad de fenoloxidasa se estimó cada 6 h durante 48 h, con 2 repeticiones por fase lunar. La actividad de fenoloxidasa presentó mayor actividad a las 14:00 h, mientras que la actividad nocturna fue baja. La actividad de la enzima se incrementó bajo luna llena en las anémonas aposimbióticas (H = 17.47, P = 0.0005). Además, encontramos una relación negativa entre la densidad de simbiontes y la actividad de fenoloxidasa (R2 = 0.50, P = 0.04). Estos resultados nos permiten sugerir que E. diaphana puede mantener una inmunidad constitutiva y constante en condiciones de laboratorio, la cual responde a ciclos biológicos, como los ciclos circadianos y lunares.
A Review on the Sublethal Effects of Pure and Formulated Glyphosate on Bees, with a Focus on Social Bee Species
Authors: Pawar Priyanshu , Jarpla Mounika , Narwade D. K. , Samreen  , Ghanghas Rajan , Sarangi Satyabrata , E Vasanthan , Rajkumari
Published: December 2024

Glyphosate, one of the most widely used herbicides globally, has been extensively applied in agriculture due to its efficacy in weed control. However, recent studies have raised concerns about its sublethal effects on non-target organisms, particularly social bee species such as honeybees (Apis mellifera), bumblebees (Bombus spp.), and stingless bees (e.g., Melipona, Trigona). While glyphosate's primary mechanism targets the shikimate pathway, which is absent in animals, emerging evidence suggests it can indirectly impact bees by altering their gut microbiota, immune responses, and behavior. Research shows that even at sublethal doses, glyphosate can impair navigation, learning, and foraging efficiency, leading to reduced colony growth and survival rates. Field and laboratory studies indicate that the impact is exacerbated when bees are exposed to formulated products containing surfactants, which increase glyphosate’s toxicity. Furthermore, the disruption of social behaviors within colonies, such as communication through the waggle dance in honeybees, has profound implications for hive health and productivity. Despite growing evidence, there remain significant gaps in our understanding of glyphosate’s long-term and chronic effects, especially across diverse ecosystems and bee species. Current research is limited by a lack of longitudinal field studies that assess the cumulative impact of low-dose exposure over multiple generations. Most studies have focused on honeybees, with less attention given to wild and native bee populations, which may respond differently to glyphosate. To address these challenges, future research must prioritize mechanistic studies, explore eco-friendly alternatives to glyphosate, and implement integrated pest management strategies to reduce agrochemical dependence. Collaboration among scientists, policymakers, and stakeholders is critical to developing evidence-based regulations that protect pollinator health. Given the essential role bees play in global food security through pollination, protecting these vital species from the sublethal effects of glyphosate is not only an ecological imperative but also a socioeconomic necessity. Immediate actions in research, policy reform, and sustainable agricultural practices are needed to mitigate the risks posed by glyphosate and safeguard the future of pollinators.