bluuebunny/crossref_metadata_2025 huggingface dataset:
GENERALIZED PASCAL’S PYRAMIDS AND COMBINATORIAL INFORMATION RETRIEVAL PROBLEMS
Authors: Kuzmin O. V.
Published: October 2024

The work studies combinatorial objects of pyramidal structure. It proposes fundamental relations for generalizations of Pascal’s triangle and pyramid. It considers problems of finding new ways of constructing information relevance indices and offers a way of constructing such an index with the help of Pascal’s generalized pyramids. Using structures of a type of Pascal’s generalized pyramids with weight factors allow construction of an index that reflects a degree of relevance of keywords, as well as makes it possible to allocate subsets of keywords with specific properties. The offered methods of the combinatorial analysis of hierarchical structures in information retrieval problems can be used in creating and analyzing knowledge databases.
Tax Legislation of the Third Reich Regarding Dogs and Dog Registration and Tax Tokens from the District of the Galicia (1940–1944)
Authors:   Ivan Franko Lviv National University, Lviv, Ukraine, Ovsinskyj Jurij
Published: October 2024

During the Second World War, the German occupation of Polish and Ukrainian lands took place. In the occupied territories, the Third Reich created a new administrative structure and implemented its own system of population taxation, in particular in the Galicia District. Among others, there was a tax for dogs, which was collected from the population on the basis of regulations and prescriptions of the new government. These resolutions regulated: the procedure for registering a dog, the amount of tax rates, preferential categories, the issuance of registration and tax tokens that were attached to the animal’s collar. A system of fines and other types of punishments for non-compliance with these orders was also established. The Magistrate reserved the right to confiscate and kill a dog whose owner was unable to pay the tax for it, and a fine of up to 500 zl was due for deliberately concealing the fact of its ownership. In large cities of the Galicia District, the tax for one dog in 1940–41 averaged up to 100 zl, in 1942–43 – 100–200 zl, in 1944–45 – 150–250 zl. In the regional towns of the District in 1941–42, it was 30–40 zl, and in the villages at the same time – 20–30 zl. There are no data for subsequent years. As a result of the practice of using such tokens, many copies have been preserved, on the basis of which we have an idea of their design, graphics, manufacturing material, etc. Such tokens are artifacts, documents of their era. In 1941, there was obviously a problem with the production of dog tokens, as evidenced by both relevant sources and the very fact of their absence in some districts for that year. At that time, the main document for registration and payment of tax for a dog was a receipt issued by local authorities. In general, the practice of registering and taxing dogs performed two important social functions: 1) regulation of the number of dogs by exterminating unregistered homeless and strays; 2) sanitary and veterinary control as a means of combating animal rabies. The results of this article may be of interest to a wide range of researchers of the history of the Second World War, the history of taxation, the history of law, the history of animal husbandry, dog owners, collectors and local historians.
Industrial Actions in Germany: Realistic in an International Context?
Authors:   University of Bremen, Däubler Wolfgang
Published: October 2024

In the EU, transborder collective action exists in theory but not in practice. Which would be the conditions to cooperate and even fight together? One should know each other, especially the underlying economic interest, the institutions, the traditions and the mentality of the other labour movement. The article tries to give concrete information about labour relations in Germany. Viewed from other European countries, it seems to be a very specific case today. This myth will be modified, if not destroyed
Variabilidad y flexibilidad salarial, retribución variable y retribución flexible
Authors:   Universidad Pontificia Comillas de Madrid, Matorras Díaz-Caneja Ana
Published: October 2024

Los incentivos y remuneraciones variables van ganando terreno, junto a los sistemas de retribución flexible o a la carta, en el marco de las políticas retributivas empresariales. Analizamos algunos de sus puntos críticos, a la luz de las complejas reformas legislativas introducidas recientemente en terrenos colindantes y de innovadores pronunciamientos urisprudenciales generadores de incrementos salariales en cascada. Con ello y con la reapertura de viejos debates y controversias, se está poniendo en evidencia la contradictoria y difícil evolución del salariado, en clave de variabilidad y flexibilidad. El presente estudio se construye con el propósito de contribuir a demarcar el espacio y potencial real con el que cuentan en la práctica como, instrumentos de modernización, flexibilización e individualización de las remuneraciones laborales
Angustias de Uberización y retos que plantea el trabajo digital al Derecho Laboral
Authors:   Universidad de Burdeos, Auvergnon Philippe
Published: October 2024

La versión de la economía colaborativa que encarnan plataformas digitales como Uber va más allá de una simple interrelación entre la oferta y la demanda de servicios. El fenómeno preocupa por el desarrollo de un trabajo «a la demanda», socialmente poco protegido. En el derecho francés, distintos dispositivos pueden permitir encuadrar esta forma de organización de una actividad profesional. Sin embargo, la mayoría de las veces, las soluciones jurídicas tradicionales no resultan apropiadas. Se impone un esfuerzo de imaginación jurídica.
Los derechos fundamentales del trabajador frente a los nuevos instrumentos de control empresarial
Authors:   Universidad de Santiago de Compostela, Villalba Sánchez Alicia
Published: October 2024

La sumisión del trabajador al poder de vigilancia y control del empresario no ha de suponer una abdicación absoluta de sus derechos fundamentales, en decir del sumo intérprete de la Constitución. No obstante, la aplicación de nuevas tecnologías que permiten la grabación y el registro de la actividad del trabajador han hecho a este más vulnerable frente a una eventual intromisión ilegítima del empresario en su esfera privada. Ante la ausencia de una normativa específica que regule el control tecnológico de la prestación de trabajo, procede abordar la interpretación que el Tribunal Constitucional ha deparado al contenido esencial del derecho a la propia imagen, a la intimidad, o al secreto de las comunicaciones del trabajador.
El marco legal del teletrabajo en Portugal
Authors:   Universidade do Porto, Abrunhosa Sousa Duarte
Published: October 2024

El teletrabajo es una forma de prestación laboral todavía poco utilizada en Portugal. Con el presente trabajo se pretende analizar el concepto de teletrabajo y su respectiva regulación en el ámbito del Derecho Portugués, así como el impacto que las recientes modificaciones legales puedan causar en el crecimiento de suya aplicabilidad práctica. Además, el autor también refleja el concepto de subordinación jurídica en el teletrabajo.
Trabajo decente y reformas laborales
Authors: Gil y Gil José Luis
Published: October 2024

El objetivo de la contribución es estudiar si las reformas laborales que han llevado a cabo países como España para hacer frente a la globalización y luchar contra la crisis financiera y económica se adecúan al concepto ético-jurídico de trabajo decente que propugna la OIT, y que constituye un marco integrador de los objetivos estratégicos de esa organización: la promoción del empleo, la protección de los derechos en el trabajo, la extensión de la protección social y el fomento del diálogo social, así como el respeto de la igualdad de oportunidades y trato para todas las mujeres y hombres. El artículo concluye que esas reformas suscitan problemas de adecuación a los instrumentos de derecho internacional del trabajo, ya sea por la vulneración de alguno de los preceptos de los Convenios de la OIT, o por apartarse de las recomendaciones y buenas prácticas que sugiere esa organización para conseguir una globalización equitativa y buscar el mejor modo de superar la crisis económica sin vulnerar los derechos de los trabajadores.
Eficiencia económica versus protección laboral en la jurisprudencia
Authors: Sempere Navarro Antonio Vicente , Arias Domínguez Ángel ,   Universidad de Extremadura
Published: October 2024

El Tribunal Constitucional ha empleado un novedoso canon de constitucionalidad “económico” para el enjuiciamiento de la constitucionalidad de la reforma laboral de 2012, introduciendo dicha variable como una más del principio de proporcionalidad, aspecto duramente criticado por varios magistrados a través de sendos votos particulares, circunstancia que se relaciona directamente con la dogmática de la reversibilidad de los derechos. El propósito de este estudio es situar en sus justos términos dicho parámetro “económico” como elemento nuclear de la hermenéutica constitucional.
QUAN ĐIỄM CỦA GIẢNG VIÊN VỀ VIỆC THỰC HIỆN CHƯƠNG TRÌNH TIẾNG ANH TRỰC TUYẾN ĐỒNG BỘ TẠI TRƯỜNG ĐẠI HỌC MỞ TP. HỔ CHÍ MINH
Authors: Thị Thục Quyên Bùi , Phương Thảo Lê
Published: October 2024

This study investigates lecturers' opinions on the non-major English program level A, which is currently being implemented in a synchronous online mode at Ho Chi Minh City Open University. A survey was conducted with the participation of lecturers who teach online for the program. Quantitative data were collected through questionnaires with the participation of all 23 lecturers, and qualitative data were obtained through interviews with 10 lecturers. The findings show that the lecturers believe that the program has prepared students quite well for the course and that both lecturers and students have the capacity and conditions to participate in this type of program. However, they still face various difficulties when teaching Speaking and Pronunciation skills as well as classroom management. These difficulties are due to the nature of synchronous online teaching, poor internet connection from students, technical issues, and most notably, some students’ attitudes that are not suitable for online learning. The lecturers also contributed some opinions on the regulations of the university on students’ behavior and exams for non-major English classes in synchronous online mode. Based on the above results, we propose some solutions to improve the effectiveness of the program.
NGHIÊN CỨU THỰC TRẠNG QUẢN LÍ HOẠT ĐỘNG DẠY HỌC MÔN CÔNG NGHỆ BẬC TIỂU HỌC Ở TRƯỜNG LIÊN CẤP VIỆT – ÚC
Authors: Hồng Cường Đỗ
Published: October 2024

Management of teaching activities for Technology subjects at Primary schools according to the General Education program in 2018 has demonstrated various changes. The Technology subject at Primary aims for students to be able to evaluate the role of use, the comment on technology products, and the design of some technical handicraft products. However, the current situation of managing Technology teaching activities in elementary schools, especially private schools, requires a thorough assessment to design and propose effective management of Technology teaching activities. This research was conducted on a typical case study at a private primary school in Hanoi city and will present the current situation of managing teaching activities in Technology subjects.
NGHIÊN CỨU CÁC YẾU TỐ ẢNH HƯỞNG ĐẾN VIỆC THỰC HÀNH PHÁT TRIỂN VỐN TỪ CHO TRẺ CHẬM NÓI 18-24 THÁNG CỦA GIÁO VIÊN MẦM NON TẠI HÀ NỘI
Authors: Thanh Tuyến Đinh
Published: October 2024

This study focuses on evaluating the impact of resources, the coordination between preschool teachers and other educational forces, and the individual capabilities of teachers in facilitating/supporting vocabulary development for children with delayed speech aged 18-24 months in Hanoi, involving 255 teachers. Grounded in theories of early childhood education, the research employs quantitative methodology through data collection from questionnaires, aiming to understand the methods and factors influencing this process. The results not only provide a comprehensive view of language development practices for children with delayed speech but also propose strategies for improving training and professional development programs for teachers. Thus, the study highlights the importance of enhancing resources and improving coordination among stakeholders to best support children's language development, while also contributing to the formulation of appropriate policy recommendations.
PHÂN TÍCH THỰC TRẠNG VÀ SỰ KHÁC BIỆT CỦA CÁC NGUYÊN NHÂN LÃNG PHÍ THỜI GIAN VỚI KẾT QUẢ HỌC TẬP CỦA SINH VIÊN
Authors: Thị Diệu Hiền Đặng , Văn Long Giang Nguyễn
Published: October 2024

To address the causes of wasting time that have or do not have an impact on students' academic achievement, this study was conducted utilizing quantitative research methods, alongside a variety of research methods, such as document research, an exploratory survey of 307 students, an official survey with 6,670 statistically valid student’s responses, interviews, exploratory factor analysis (EFA), scale reliability analysis, descriptive statistics, and inferential statistics. Consequently, all of the 11 causes of wasting time that belong to the two categories of objective and subjective causes are at the influential level. Whether in the group of objective or subjective causes, reasons related to the use of technology are the leading cause of wasting students' time. In addition, the study also found that there is a significant difference between student's academic results, with the main trend of students with fair academic performance having more wasted time when compared to groups of students with good and excellent grades. Therefore, to have good learning results, students need to study and practice time management skills to increase the efficiency of time use and avoid time-consuming factors.
MỐI QUAN HỆ GIỮA HÀNH VI TRỪNG PHẠT THỂ CHẤT CỦA CHA MẸ VÀ HÀNH VI GÂY HẤN CỦA VỊ THÀNH NIÊN: VAI TRÒ TRUNG GIAN CỦA SỰ GẮN BÓ KHÔNG AN TOÀN
Authors: Thị Cẩm Tú Trần , Bá Tuấn Vũ
Published: October 2024

This study examines the relationship between prior parental physical punishment and future aggressive behavior in children, as well as the mediating role of anxious and avoidant attachment in the relationships. Using an 8-month longitudinal study design, data were collected at 3 waves, with a 4-month interval across waves. 762 students participated at Wave 1 (Mage = 12.1 (SD = 1.14), 48% female). The number decreased to 484 at Wave 2 and 368 at Wave 3. The Harsh Punishment was used to measure physical punishment at Wave 1, the Experiences of Close Relationship (short version) was used to measure avoidant and anxious attachment at Wave 2, and the Aggression Scale was used to measure aggressive behavior at Wave 3. Results showed that parents' physical punishment behavior significantly predicted the development of future aggressive behavior, and that anxious attachment played a mediation role in the relationship. These findings suggest the urgent need for developing measures to treat physical punishment and parent-child attachment as a solution to effectively address the prevalence of school violence in Vietnam.
VẬN DỤNG PHƯƠNG PHÁP DẠY HỌC KHÁM PHÁ TRONG DẠY HỌC PHƯƠNG TRÌNH LƯỢNG GIÁC Ở NƯỚC CỘNG HÒA DÂN CHỦ NHÂN DÂN LÀO
Authors: Đình Phượng Vũ , Sengvongdeuane Nhotlusay
Published: October 2024

According to educational researchers, effective learning is not only just sitting in classes spectating other activities, and memorizing available imparted knowledge,  but learners also  should participate in  the discovery process of new knowledge guided by instructors. It is necessary to apply the discovery learning method to teaching the subjects in general and teaching Mathematics in particular in the direction of developing the competencies and qualities for students. This paper focuses on researching the concept of the discovery learning method and its characteristics. Based on researching the Mathematics curriculum and practical teaching in The Lao People's Democratic Republic, this paper proposes applying the discovery learning method to teaching trigonometric equations at high schools in the Lao People's Democratic Republic.
Study on compaction characteristics and discrete element simulation for rubber particle-loess mixed soil
Authors: Kou Wen-qi , Bai Jian-guang , Li Hai-jun , Liu Qing-hong
Published: October 2024

The rapid surge in traffic volume in China has resulted in a substantial accumulation of waste tires. By harnessing the lightweight and deformable characteristics of tire rubber particles, they are combined with soil to form rubber particle-loess mixed soil, which is progressively being embraced in civil engineering as a pivotal approach towards attaining green and sustainable development. In this study, waste tire rubber particles were integrated into loess to generate rubber particle-loess mixed soil, and compaction tests were conducted to investigate its compaction characteristics. Furthermore, PFC3D (Particle Flow Code 3D) was utilized for simulating the bearing ratio test of rubber particle-loess mixed soil, thereby validating the feasibility of numerical simulation for calculating CBR (California bearing ratio) values and exploring the relationship between micromechanical characteristics and macroscopic characteristics of such mixtures. The findings indicate that the maximum dry density of rubber particle-loess mixed soil significantly decreases with an increasing content of rubber particles. The utilization of PFC3D discrete element software proves efficacious in examining the bearing capacity of this mixture. Notably, when 20 mesh rubber particles constitute 20% by volume, the CBR value reaches its pinnacle and exhibits optimal bearing capacity. From a micromechanical perspective, the variation in internal porosity of rubber particle-loess mixed soil is positively associated with changes in macroscopic optimal water content, and negatively associated with changes in macroscopic CBR value. incorporating rubber particles enhances resistance against external forces while diminishing deformation within loess. This study provides a guidance for the efficient utilization of waste tires and the improvement of loess’s characteristics.
Профессиональная адаптация инвалидов в Курской области
Authors: Агронина Наталья Иосифовна
Published: October 2024

В статье рассматривается специфика проблемы трудоустройства инвалидов в Российской Федерации, а также меры принимаемые для содействия занятости на муниципальном уровне. Проанализированы актуальные данные мониторингов статистических служб РФ, показывающие востребованность мер сопровождения адаптации лиц с инвалидностью на рынке труда. На примере инклюзивного центра «Дышим вместе», работающего в городе Курске, представлен муниципальный опыт реализации волонтерских, образовательных и общественных проектов по нормализации жизнедеятельности, социальной и профессиональной адаптации инвалидов. Описанный положительный опыт данного центра может быть масштабирован и тиражирован в регионах России.
Study Fatigue in Materials of Drill Pipes
Authors: Argirov J. , Yankova R. , Antonov G.
Published: October 2024

Upon examination of a fracture burst, it was found out that the main reason for this is the fatigue of the material in the annular section of the pipes. Analysis was made of the stress state and its impact on the nature of the destruction. In a working conditions, especially in rotor drilling, a direct correlation between the loss of stability of the column in the compression zone and the destruction of drill piping due to fatigue failures in material is established. Object of study is the nature of the destruction of defective drill pipe
Advantages of MAG-STT Welding Process for Root Pass Welding in the Oil and Gas Industry
Authors: Pandzic Adi , Hajro Ismar , Tasic Petar
Published: October 2024

This paper describesthe basics of modern MAG-STT welding process and its advantages for root pass welding of construction steels in oil and gas industry. MAG-STT welding process was compared with competitive arc welding processes (SMAW and TIG), which are also used for root pass welding on pipes and plates. After experimental tests, the obtained results are analyzed and presented in this paper
Mesenchymal Stem Cell Therapy Mitigates Acute and Chronic Lung Damages of Sulfur Mustard Analog Exposure
Authors: Tapak Mahtab , Sadeghi Somaye , Ghazanfari Tooba , Mosaffa Nariman , Mirsanei S. Zahra , Hashemi Seyed Mahmoud Masiha
Published: October 2024

Sulfur mustard (SM) is an established chemical weapon that can result in severe damage to parts of the body. Currently, there are no effective treatments available for SM-caused damage.  We aimed to investigate the therapeutic potential of adipose-derived mesenchymal stromal cells (AD-MSCs) and conditioned medium (CM-MSCs) in acute and chronic pulmonary mouse models caused by 2-chloroethyl ethyl sulfide (CEES), an SM analog.
The mice were divided into 4 experimental groups:(1) CEES+AD-MSCs, (2) CEES+CM-MSCs, (3) CEES, and (4) control. The model observation time was divided into 7 days for the short and 6 months for the long term. AD-MSCs were injected into mice via intraperitoneal injection 24 hours after CEES exposure. The therapeutic effects of AD-MSCs on pulmonary tissue damage were assessed using a histopathologic assay, measuring the neutrophil count, and bronchial alveolar lavage fluid (BALF) protein level. The levels of inflammatory and anti-inflammatory cytokines were evaluated using the enzyme-linked immunosorbent assay as the outcomes of interest.
Lung damage progression was reduced by AD-MSC treatment in mice after CEES injection into the peritoneum. The proportion of CD11b+F4/80+ macrophages in the peritoneum was significantly lowered by AD-MSC treatment following CEES exposure. AD-MSC administration also reduced the level of pro-inflammatory cytokines, BALF protein, and nitric oxide levels in the peritoneal cavity.
By reducing inflammation and enhancing tissue healing, AD-MSCs and CM-MSC help prevent acute lung damage caused by CEES. The current study supports the use of a mouse model as a solid experimental foundation and indicates potential use for future cell treatment.
Allogeneic stem cell Transplant in Hematological Disorders: A Decade of Experience
Authors: Arif Salman , Ali Natasha , Shaikh Usman , Adil Salman , Jehanzeb Hamzah
Published: October 2024

Background: Allogeneic hematopoietic cell transplantation (allo-HCT) is a complex procedure with the potential to provide curative treatment for various hematological disorders. This study aims to evaluate the outcomes of allo-HCT in hematological diseases and identify significant complications in a single-center setting.
Materials and Methods: We conducted a retrospective analysis of 180 patients with hematological diseases who underwent allo-HCT between January 2011 and December 2021. Key outcomes, including indications for transplantation, overall survival, engraftment time, relapse rates, graft-versus-host disease (GVHD), and transplant-related mortality (TRM) were assessed.
Results: The most common indications for allo-HCT were benign hematological diseases, particularly aplastic anemia, and thalassemia major. Despite the majority of patients receiving fully matched transplants, Acute GVHD was observed in 30% of the cohort. Graft failure occurred in 13 patients, with primary and secondary graft failure rates of 1.6% and 5.5%, respectively. Sepsis emerged as the primary cause of non-relapsed mortality at day 100 and beyond. The overall survival rate in this study was 62%, with 79% of patients disease-free on their last visit.
Conclusion: This study provides valuable insights into the treatment strategies and patient care of allo-HCT for hematological disorders by offering a comprehensive overview of multiple relevant outcomes. The findings underscore the significance of addressing complications and risk factors associated with allogeneic transplantation, including GVHD and infections. Future research should focus on further optimizing transplantation techniques to minimize complications and enhance patient survival.
Uncommon Presentation of Multiple Myeloma: Pleural Effusion and Extensive Extramedullary Involvement
Authors: PK Kiran , Prakash G Hari , KR Sahana , Kumar D Sunil
Published: October 2024

A 60-year-old female presented with abdominal pain, weight loss, and fatigue. Imaging revealed a pancreatic mass, bilateral pleural effusion, ascites, and lytic bony lesions. Investigations confirmed multiple myeloma with lambda light chain disease. Positron emission tomography-computed tomography (PET-CT) scan demonstrated extensive metabolically active soft tissue masses involving the pancreatic region, retroperitoneum, mediastinum, paravertebral regions, and multiple skeletal lesions with extraosseous soft tissue involvement, along with bilateral pleural effusions with metabolically active pleural and extrapleural deposits. The patient was initiated on a bortezomib, cyclophosphamide, and dexamethasone chemotherapy regimen with therapeutic thoracentesis for pleural effusion management. After two cycles, the patient showed remarkable clinical improvement. A repeat PET-CT scan revealed significant interval regression of soft tissue masses, metabolic activity resolution, and regression of pleural and extrapleural deposits. The extensive skeletal lytic lesions showed morphological stability but regression of associated metabolic activity and extraosseous soft tissue. This case highlights the potential of novel agent-based regimens in achieving exceptional responses in multiple myeloma patients with extensive extramedullary disease (EMD), including uncommon manifestations like pleural effusion. Early recognition and prompt initiation of appropriate therapy are crucial for improving outcomes in such cases.
Sequential Occurrence of Eosinophilic Gastrointestinal Disease in a Case of Waldenström’s Macroglobulinemia in Remission: An Unusual Report with Review
Authors: Jitani Ankit , Mundhe Mayur Babasaheb , Husain Kazi Wajid , Menghani Hemant , Desai Maharshi , Nair Velu
Published: October 2024

Waldenström macroglobulinemia (WM) is a rare lymphoproliferative malignancy presenting with para-proteinemia. The symptoms are attributable to both lymphoproliferation and IgM flare. Gastrointestinal manifestations are not uncommon. It is an indolent disease with good response to chemoimmunotherapy but with possible persistence of asymptomatic paraproteinemia. Resurgence of gastrointestinal symptoms in a patient of WM maintaining reasonable response warrant a thorough search for alternate pathology. Herein we describe a rare case of sequential occurrence of WM with Eosinophilic Gastrointestinal Disease posing a diagnostic and therapeutic challenge.
Medication Adherence and Practices in Pediatric Patients
Authors: Shanbhag Sweta , Avabratha K Shreedhara , H Sudhir Prabhu , K Bhagyalakshmi
Published: October 2024

Background: Improper medication practices and non-adherence are the biggest challenges faced by pediatricians in outpatient practice. Hence this study was aimed at determining the medication practices and factors affecting adherence.
Methods: A cross sectional descriptive study was conducted at a tertiary care hospital in Southern India over a period of 3 months (January to March 2023), to study medication adherence and parental medication practices in pediatric patients. A pre structured questionnaire was administered to parents of 320 children.
Results: Majority of the parents (55%) had children aged 1-5 years of age. It was noted that most of the families (89%) were above poverty line (APL). About 34% parents were educated till graduate level and 17% were educated beyond post graduate level. Frequency of medication adherence in our study was found to be 78%. It was noted that parents with education of graduate level and above, those belonging to APL families and the ones with no fear of adverse drug reactions showed higher medication adherence as compared to other parents and this association was found to be statistically significant (p <0.001). Majority of the parents (80%) reported that their children preferred liquid formulations, of which 57% preferred fruit flavoured ones. Around 51% parents preferred twice daily dosing of medications. While 47% parents used previous prescriptions, 39% bought over the counter medicines, especially paracetamol.
Conclusion: Knowledge about medication practices and factors affecting adherence is important in order to provide quality health care. Actively involving children and parents while prescribing medications with health education goes a long way in improving adherence.
Comprehensive Review of the Potential Anti-Breast Cancer Properties of Various Medicinal Plants
Authors: Kusane Harshada A. , Kangralkar Vishnu A.
Published: October 2024

Breast cancer is the most frequent cancer in women throughout the globe, and its management can be difficult due to its complex etiology. Treatment with chemotherapy, surgical procedures, radiation treatment, and hormone therapy are among the most frequently utilized treatments. However, complications and resistance to multiple drugs can cause challenges. This overview addresses how organic medicinal products obtained from edibles and plants can assist with treatment of Breast cancer. The article scrutinizes the ways by which natural substances may exert beneficial impact in the prevention and management of breast carcinoma as well as offers knowledge regarding the therapeutic plant, including its family, part used, kind of extraction, and molecular mechanisms in breast carcinoma. Following an exhaustive analysis of the various plants, we discovered that Peganum normata, Ammi visnaga, Camellia sinensis, Curcuma longa, and Allium sativam L. had potential anti-breast cancer activities. These data were gathered from PubMed, Scopus, and Google Scholar.
Standard dose Cytarabine-Induced Encephalopathy in an Acute Myeloid Leukemia Patient: A Case Report
Authors: Ebrahimpour Mehrshad , Moghadam , Samin Ghorbani , Kamandi Mostafa , Arasteh Omid
Published: October 2024

The mainstay of treatment for acute myeloid leukemia (AML), cytarabine, is known to induce encephalopathy, usually at high doses. During induction chemotherapy, a 38-year-old woman with non-M3 AML experienced encephalopathy following the administration of standard-dose cytarabine. The patient's mental state deteriorated, and she exhibited symptoms of physical weakness, confusion, and lethargy. There were no abnormalities in the brain parenchyma discovered by a CT scan. After a diagnosis of cytarabine-induced encephalopathy, cytarabine treatment was abruptly discontinued. Levetiracetam was used for managing seizures, intravenous hydration, and medication management, all of which were put into place as supportive measures. Over the next few days, the patient's mental state got better, and ten days later, she was fully conscious again. The encephalopathy and cytarabine were likely related, according to the Naranjo scale. Cytarabine was not reintroduced due to the patient's recovery and to prevent any potential problems. Rather, an alternate treatment regimen consisting of etoposide and mitoxantrone was initiated. This case emphasizes how crucial it is to take cytarabine-induced encephalopathy into account as a possible side effect when treating AML, even at lower doses of the medication. to minimize patient morbidity and ensure a successful treatment course, healthcare practitioners need to be on alert for signs and symptoms of this condition. Early detection and rapid cessation of cytarabine medication are critical steps in this regard.
A NOVEL ELECTROCHEMICAL BIOSENSOR BASED ON CREATININE DEIMINASE FOR CREATININE ANALYSIS
Authors: Bakhmat V. A. , Arkhypova V. M. , Soldatkin O. O. , Dzyadevych S. V.
Published: October 2024

This work presents the development of a new electrochemical biosensor based on creatinine deiminase for the determination of creatinine concentration in biological samples. The optimal method for immobilizing bioselective elements on the electrode surface was selected, specifically the covalent binding of creatinine deiminase in a BSA matrix using glutaraldehyde. The biosensors prepared in this way exhibited the highest sensitivity to creatinine and high reproducibility in the fabrication of biomembranes. The biosensor demonstrated a low limit of detection of creatinine, high signal stability (RSD = 3%), significant storage stability, and a wide linear range, enabling the detection of both normal and pathological creatinine concentrations in biological fluids. The study also investigated the influence of working solution parameters, such as ionic strength, buffer capacity, pH, and protein content, on the biosensor’s performance. The main analytical characteristics of the proposed electrochemical biosensor indicate its potential use for monitoring creatinine concentration in biological samples.
THE GUARANTEES OF THE CONCEPT OF THE PRINCIPLE OF EQUALITY OF ALL PARTICIPANTS IN THE ADMINISTRATIVE PROCESS BEFORE THE LAW AND THE COURTS IN UKRAINE
Authors: Ilieva N. V. , Kulia V. S.
Published: October 2024

The article analyzes approaches to understanding the concept of guarantees, the essence of guarantees, general guarantees of the principle of equality of all participants in court proceedings and special guarantees of the principle of equality of all participants in the administrative process before the law and the court. The primary definitions of the concept of guarantees, the main guarantees of the general principle of equality were studied, the principle of equality of participants in court proceedings was separately studied, the classification of such guarantees was considered taking into account the specifics of the principle of administrative proceedings.
This article examines the concept of guarantees of the principle of equality in the administrative process, examines the essence and types of legal guarantees and determines the place of guarantees of the principle of equality of all participants in the administrative process among them, examines the main types of guarantees of the principle of equality of all participants in the administrative process by the form of consolidation and levels of support.
The article examines and classifies guarantees of the principle of equality according to various criteria, such as: by the form and level of consolidation, by the levels of provision, by the nature of the action, by subject composition, by legal nature, by the form of implementation. The classification of guarantees allows a better understanding of how the principle of equality is ensured at different levels of the legal system, and helps to identify potential guarantees and mechanisms for the implementation of the principle of equality of all participants in the administrative process.
The article offers a definition of the guarantees of the principle of equality of all participants in the administrative process before the law, directly gives such guarantees and discloses their essence, including taking into account the specifics of the properties of administrative proceedings.
ENVIRONMENTAL ENTREPRENEURSHIP: ROLE IN SOLVING ENVIRONMENTAL CHALLENGES AND ENSURING SOCIAL INCLUSION
Authors: Lomachynska I. A. , Fedorchenko Y. G.
Published: October 2024

The article studies the essence of environmental entrepreneurship and its role in solving modern environmental challenges and social problems. Balancing economic, social, and ecological goals, environmental entrepreneurs at all stages of their activities prioritize sustainable development and responsible and reasonable strategic decisions that form the long-term value of entrepreneurial activity. Thus, environmental entrepreneurship, introducing social and ecological innovations, rational use of resources and minimization of negative impact on the environment, ensuring a continuous recycling and absorption process of any material, promotes economic growth and social welfare of all segments of the population; promotes social inclusion and integration, a realization of human potential, business activity, entrepreneurial ability; expands opportunities for people with special needs, and marginalized; improves the level and quality of their life, reduces the differentiation of society, etc.
Analysis of international experience has revealed that, in modern conditions, environmental entrepreneurship has received international recognition as a response to global environmental challenges. At the same time, international cooperation, standardization, and technology exchange are key factors in the development of ecological entrepreneurship at the international level. Legislative support, financial incentives, and increased consumer awareness create a favorable environment for green (sustainable) businesses.
Despite the challenges of a large-scale war, progress is being made in the development of environmental entrepreneurship in Ukraine, in particular through the restoration of infrastructure and the introduction of European environmental standards.
It is generalized that the development of environmental initiatives in the context of the post-war reconstruction of Ukraine will ensure the realization of the potential to stimulate economic development, create new opportunities for business and employment, generate profit and income, ensure the restoration of affected areas and rural development, promote the transition to a low-carbon economy, solve social problems. However, the implementation of these tasks requires compliance with the following principles: an integrated approach to the balance of economic, social, and environmental components of environmental entrepreneurship in the interests of sustainable development; investments in education to spread knowledge and skills in the formation of sustainable development public culture; impact investments, inclusive social and environmental innovations as the basis for economic growth; cooperation between governments, businesses, society, and communities as the basis for implementing sustainable development initiatives.
Osnove matrične analize
Authors: Petek Tatjana
Published: October 2024

Uvodoma predstavimo matrični račun, sisteme linearnih enačb in determinanto. Nato spoznamo vektorski prostor kot algebrsko strukturo, predstavitev vektorjev z matričnimi stolpci glede na izbrano bazo, pojem vektorskega podprostora ter pomembne podprostore, povezane z matrikami. Nadalje se na kratko posvetimo linearnim preslikavam in njihovi matrični predstavitvi. Analiza značilnih podprostorov, ki so prirejeni matriki, omogoča obravnavo določenih lastnosti ustreznih linearnih preslikav. Vektorski prostor dodatno opremimo še s skalarnim produktom, kar omogoča vpeljavo pojma ortogonalnosti, ta pa pripelje do učinkovite optimizacijske metode, metode najmanjših kvadratov, ki je v inženirski praksi zelo pogosta in uporabna. Obravnavamo osrednji problem linearne algebre oziroma matrične analize, problem lastnih vrednosti. S tem je povezana diagonalizacija matrike, Jordanova normalna oblika in unitarna podobnost trikotni matriki. Slednja na enostaven način omogoči obravnavo hermitskih in simetričnih matrik, ki imajo v inženirski uporabi posebno mesto. Na koncu nanizamo še nekaj primerov uporabe teorije iz prejšnjih poglavij, ki se nanašajo na spektralne lastnosti matrik. Posebej izpostavimo razcep s singularnimi vrednostmi, ki ima zelo široke možnosti uporabe. Učbenik zaključimo s posplošenimi inverzi matrik.
Łódzcy bohaterowie 1918 roku
Authors: Piskała Kamil , Szymański Marcin , Czernielewski Konrad A. , Lesiakowski Krzysztof , Daszyńska Jolanta A. , Czekalska Adrianna , Olejnik Leszek , Kita Jarosław
Published: October 2024

Książka poświęcona jest wybitnym postaciom związanym z Łodzią – zasłużonym dla wyzwolenia dawnego „polskiego Manchesteru” oraz restytucji Rzeczypospolitej w 1918 roku. Przedstawiono w niej losy polityków, samorządowców, społeczników i wojskowych; narodowców, chadeków, piłsudczyków i socjalistów. Sportretowano ludzi, dla których miasto nad Łódką stało się drogą do wielkiej polityki, pełnienia najważniejszych funkcji państwowych i osiągnięcia wysokich stopni oficerskich w Wojsku Polskim oraz tych, którzy pozostali wybitnymi działaczami politycznymi i społecznymi w skali lokalnej, realizując się w pracach samorządowych. Niektórzy z nich byli rodowitymi łodzianami, inni związali się z miastem nad Łódką na różnych etapach życia. Wszyscy jednak – choć w różnych dziedzinach – odcisnęli piętno na dziejach Łodzi: jej życiu politycznym, społecznym, gospodarczym i kulturalnym.
Quality Improvement Initiative: Identifying Barriers to Reducing Time to First Feed With Human Milk in Low Birth Weight Infants
Authors: Chubey Rebecca , Fraser Deb , Braganza Veronica , Yi Man , Fraser Kyla , Friesen Rachael , Qui Zhong Ming
Published: October 2024

Early exposure to human milk and time to first trophic feed in low birth weight (LBW) infants (<2 kg) is associated with a decreased risk of mortality, sepsis, and length of hospital stay. This project, focused on infants born at less than 2 kg, aimed to identify the mean time to first feed after birth, identify barriers to initiation of the first feed, and meet the target of having 90% of infants receive their first feed within the first 6 hours of life. This quality improvement (QI) project occurred in a thirty-bed level III NICU over 29 months using two Plan-Do-Study-Act (PDSA) cycles. A first-feed audit tool and a multifaceted educational plan were at the forefront of this initiative. Interventions were multidisciplinary, targeted, and extended to all healthcare team members caring for LBW infants, including staff of Labor and Delivery, the NICU, and the Child Health Transport Team. At the end of the QI project, 91.3% of inborn infants and 27.5% of outborn infants were being fed by 6 hours of age, compared with 78.8% and 12.5%, respectively, prior to the project. The mean time to first feed for inborn infants after the PDSA cycles was reduced to 4.4 hours, having a decrease of 80 minutes. A multidisciplinary approach was a key factor in the success of this QI initiative. Increasing staff education and improving clinical practice guidelines regarding the importance of early exposure to human milk are associated with reducing first feed times after birth.
The Influence of Economic Stability on Neonatal and Family Well-Being
Authors: Marcellus Lenora , Amundsen Miranda
Published: October 2024

Economic stability is one of the five domains of determinants of health influencing the well-being of families and communities. In this column, the impacts of economic instability, including poverty, employment, food insecurity, and housing instability, will be described. These challenges have unique impacts during pregnancy and the early years, with inequitable and accumulating health burdens over a lifetime. Actions that nurses can take within the NICU setting are described and opportunities for community and policy advocacy are identified.
Forms of perpetuating the historical memory of the Heroes of the Soviet Union in urban toponymy (using the example of commissar Moskovsky Street in Tambov)
Authors: Kvadiaev S. S.
Published: October 2024

Importance. The activities of the Tambov city authorities, public organizations and institutions, their motives in the work on the preservation of military historical memory in the urban enviro nment during the second half of the 20th – beginning of the 21th century on the example of perpetuating the memory of the first Hero of the Soviet Union from Tambov region – A.N. Moskovsky, are considered. The importance of the research lies in the fact that the use of trends in modern historical science, namely, an interdisciplinary approach to research, political history and historical urbanism, allows us to obtain qualitatively new knowledge about the activities of the Russian cities authorities (based on Tambov materials) to preserve military historical memory in urban toponymy and objects of monumental art during the second half of the 20th century – the beginning of the 21th century.

Materials and Methods. The methodological basis of the research is based on the principles of consistency, historicism, and objectivity. Comparative historical, problem and chronological methods are used. The research is based on such general scientific methods as analysis, synthesis, generalization, and systematization. The main sources of the research are archival materials stored in the State Archive of Tambov Region, the State Archive of Socio-political History of Tambov Region, published and posted on the Internet, as well as materials in the funds of the Museum and Exhibition Center of Tambov Region.

Results and Discussion. The features of the ideological work of local authorities on the development of military historical memory are analyzed. The patterns and continuity of approaches in the military historical work of the city authorities at different chronological stages are revealed. The mechanisms of preserving the memory of a particular hero, senior political instructor, commissar A.N. Moskovsky, are investigated. The forms of historical and patriotic information about the objects of urban toponymy and monumental art created during the development of the urban environment, concerning the perpetuation of the memory of A.N. Moskovsky, are highlighted.

Conclusion. As a result of studying the problem, conclusions are drawn about the multi-faceted approach in the work of city authorities, institutions and public organizations for the preservation of military historical memory in the region.
Vetőmageredet jelentősége a természet-helyreállítási gyakorlatban: érvek és ellenérvek a hazai szabályozás tükrében
Authors: Török Katalin , Valkó Orsolya , Deák Balázs
Published: October 2024

Az ENSZ „ökoszisztémák helyreállításának évtizede” világszerte új lendületet adott az élőhely-restaurációs projekteknek. Bár általános egyetértés van azzal kapcsolatban, hogy szabályozni kell a restaurációs célokra használt honos fajok magjainak transzferjét, sok esetben a magok származásával kapcsolatos vita nehézségeket okoz a gyakorlati megvalósításban. Vizsgálatunkban elemeztük a helyi és távoli forrásból származó magok használatának előnyeit, hátrányait, valamint felmértük a hazai restaurációval foglalkozó kutatók, gyakorlati szakemberek és más természetvédelmi területen dolgozó kutatók véleményét a kérdésről. A további kutatások és az azonnali beavatkozások prioritásával kapcsolatos attitűdök jelentősen eltértek a kutatók és a gyakorlati szakemberek körében. Eredményeink alapján javaslatot tettünk egy döntéstámogató keretrendszerre, amely segíthet a konszenzus kialakításában.