bluuebunny/crossref_metadata_2025 huggingface dataset:
THE IMPACT OF TOP MANAGEMENT SUPPORT AND ORGANIZATIONAL STRUCTURE ON ACCOUNTING INFORMATION SYSTEMS QUALITY
Authors: Darma Jufri , Nurwendari Weny , Sriwedari Tuti , Herliani Rini
Published: April 2024

This study aimed to investigate how the quality of accounting information systems in higher education institutions in North Sumatra is influenced by the organizational structure and the support from top management. A survey involving 67 participants, who are users of accounting information systems at colleges in North Sumatra, was conducted. Data was gathered through the administration of a questionnaire. The collected data was analyzed using Structural Equation Modeling with a Partial Least Square approach, utilizing the Smart-PLS software. The findings of the study provided empirical evidence indicating that both top management support and organizational structure significantly impact the quality of accounting information systems in higher education institutions located in North Sumatra.
Pengaruh Pengungkapan Informasi Lingkungan, Sosial, Tata Kelola, Ekonomi, dan Pendekatan Manajemen Terhadap Kebijakan Dividen
Authors: Ihsan Muhammad , Zuraida Zuraida
Published: April 2024

This research aims to determine the influence of Environmental, Social, Governance (ESG) disclosure, Economic disclosure, and Management Approach on Dividend Policy proxied by Dividend Payout Ratio and Dividend Yield. The study incorporates five control variables: company size, age, leverage, profitability, and liquidity. The data used in this research are secondary data obtained from the financial and sustainability reports of companies listed on the Indonesia Stock Exchange in the IDX ESG Leaders Index for the period 2020-2022. The results indicate that the disclosure of environmental, governance, and management information does not have a significant influence on dividend policy, both in terms of Dividend Payout Ratio and Dividend Yield measurements. This finding suggests that environmental, governance, and management disclosures cannot be used as a basis for decision-making for stakeholders. Social disclosure has no significant influence on Dividend Payout Ratio, but it has a significant negative impact on Dividend Yield, indicating that social disclosure affects dividend policy negatively. On the other hand, economic disclosure shows a significant influence on dividend policy, both in terms of Dividend Payout Ratio and Dividend Yield measurements.
Okul Öncesi Dönem Çocuklarının Öz Düzenleme Becerileri İle Sosyal Becerileri Arasındaki İlişkinin İncelenmesi
Authors: Samar Yasin , Demiriz Serap
Published: April 2024

Amaç: Bu çalışmanın amacı okul öncesi dönem çocuklarının öz düzenleme becerileri ile sosyal becerileri arasındaki ilişkinin incelenmesidir. Bu amaç kapsamında okul öncesi dönem çocuklarının öz düzenleme becerilerinin ve sosyal becerilerinin çocuğun cinsiyeti, aile tipi, anne öğrenim düzeyi, baba öğrenim düzeyi ve anne çalışma durumu değişkenlerine göre anlamlı farklılık gösterip göstermediği belirlenmiştir.

Yöntem: Araştırmanın örneklemi kolay ulaşılabilir durum örneklemesi ile seçilen 478 çocuktan (241 kız, 237 erkek) oluşmaktadır. Araştırmanın verileri Sezgin ve Demiriz (2015) tarafından Türkçe’ye uyarlanan Baş-Ayak-Diz-Omuz Dokunma Yönergeleri (BADO-DY) ve Ömeroğlu vd. (2014) tarafından geliştirilen Okul Öncesi Sosyal Beceri Değerlendirme Ölçeği (OSBED) kullanılarak elde edilmiştir. Değişkenleri ile ilgili verilerin normal dağılım göstermesi sebebiyle analizde bağımsız örneklem T-testi ve ANOVA testi kullanılmıştır. Çocukların öz düzenleme becerileri ile sosyal becerileri arasındaki korelasyon ilişkisine Pearson korelasyon analizi ile bakılmıştır.

Bulgular: Araştırma sonucunda çocukların öz düzenleme beceri puanları ile sosyal beceri puanları arasında pozitif yönde anlamlı bir ilişki olduğu saptanmıştır. Çocukların öz düzenleme ve sosyal beceri düzeylerinde çocuğun cinsiyetine, aile tipine, anne öğrenim düzeyine, baba öğrenim düzeyine ve anne çalışma durumuna göre anlamlı fark gösterdiği tespit edilmiştir.

Sonuçlar ve Öneriler: Ebeveynlere öz düzenleme ve sosyal beceri hakkında eğitimler (konferans, seminer vb.) verilebilir. Sınıfta çocukların öz düzenleme ve sosyal becerilerinin gelişimine destek olacak ve ailelerinde katılabileceği etkinlikler düzenlenebilir. Farklı örneklem grubu ile benzer çalışmalar yapılabilir ve sonuçlar karşılaştırılabilir.
Okul Öncesi ve Sınıf Öğretmenlerinin Psikolojik Sağlamlık Düzeylerinin Bazı Değişkenler Açısından İncelenmesi
Authors: Şen Reyhan , Köse Akif
Published: April 2024

Amaç: Bu araştırmada okul öncesi ve sınıf öğretmenlerinin psikolojik sağlamlık düzeylerinin bazı demografik değişkenler açısından incelenmesi amaçlanmıştır.

Yöntem: Nicel bir araştırma olan bu çalışma tarama modelinde gerçekleştirilmiştir. Araştırmanın evrenini 2022-2023 eğitim-öğretim yılında Aydın ilinde kamuya ait anaokulu ve ilkokullarda görev yapan öğretmenler; örneklemini ise basit seçkisiz örnekleme yöntemiyle seçilen 374 öğretmen oluşturmaktadır. Araştırmada veri toplama aracı olarak “Kısa Psikolojik Sağlamlık Ölçeği” ve “Kişisel Bilgi Formu” kullanılmıştır. Verilerin analizinde standart sapma ve aritmetik ortalama değerleri kullanılmış, psikolojik sağlamlığa ilişkin alınan puanların demografik özellikler yönünden farklılaşma durumunu tespit etmek için t-Testi, Tek Yönlü Varyans Analizi (ANOVA) ve Kruskal Wallis-H testlerinden faydalanılmış, anlamlı bulunan F değerinde fark olan grupları belirlemek için Scheffe testi, Kruskal Wallis-H testi sonucunda anlamlı çıkan gruplardaki fark olan grupları belirleyebilmek için de Mann Whitney-U testi uygulanmıştır.

Bulgular: Öğretmenlerin psikolojik sağlamlığa ilişkin görüşlerinin bazı demografik değişkenler yönünden farklılaşma durumuna bakıldığında cinsiyet, medeni durum, yaş, mesleki kıdem, görev yapılan kurumun bulunduğu yerleşim yeri, okutulan sınıf ve yaş düzeyi ile istihdam tipi değişkenleri bakımından anlamlı bir farklılaşmanın olmadığı; eğitim durumu, branş, çalışılan kurum ve sınıftaki öğrenci sayısı değişkenleri açısından ise anlamlı farklılıkların olduğu bulgulanmıştır.

Sonuçlar ve Öneriler: Araştırma sonucunda öğretmenlerin psikolojik sağlamlık düzeylerinin yüksek olduğu; öğretmenlerin psikolojik sağlamlıklarının lisansüstü eğitim mezunu olan öğretmenler lehine anlamlı bir farklılık gösterdiği; sınıftaki öğrenci sayısı arttıkça öğretmenlerin psikolojik sağlamlık düzeylerinin azaldığı sonuçlarına ulaşılmıştır. Okul öncesi ve sınıf öğretmenlerinin yüksek düzeydeki psikolojik sağlamlıklarını sürekli kılmak için onların mesleki gelişimlerini destekleyici eğitsel içerikli seminerler, hizmet içi eğitimler ve yapılandırılmış rehberlik programları düzenlenebileceği, öğretmenlerin lisansüstü eğitim alabilmeleri için destekleyici nitelikte düzenlemeler yapılabileceği, sınıf mevcutları düzenlenirken öğretmenlerin psikolojik sağlamlıklarını olumsuz etkileyecek uygulamalardan kaçınılması gerektiği önerileri getirilmiştir.
Hidradenitis supurativa en el embarazo: un caso de difícil manejo
Authors: Corredor López Karen Sofía , Rodríguez Estupiñán Aura Catherine , Herrera Buitrago María Camila , Salamanca Mora Sonia
Published: April 2024

La hidradenitis supurativa es una enfermedad inflamatoria crónica  de la piel, caracterizada por lesiones supurativas localizada principalmente en áreas intertriginosas con presentación clínica variable desde nódulos dolorosos hasta trayectos fistulosos que generan deformidad anatómica. Afecta predominantemente a mujeres en edad fértil , dado la fluctuación constante de las hormonas sexuales y cambios metabólicos que aún no están bien descritos.
Se presenta el caso clínico de una paciente femenina de 25 años, con antecedente de Hidradenitis supurativa, quien presenta durante el embarazo  exacerbación de las lesiones, múltiples tractos fistulosos y cicatrices en puente que comprometen región axilar, región perineal y genital; a través del cual se muestra un abordaje terapéutico multidisciplinario con el servicio de dermatología y obstetricia.
Dermatitis infectiva en paciente con paraparesia espástica tropical (HTLV-1 positivo): a propósito de un caso
Authors: Jordan-Díaz Ana María , Renteria Lozano Sindy Paola , Rueda plata Ricardo Augusto
Published: April 2024

La paraparesia espástica, es una enfermedad linfoproliferativa asociada al retrovirus linfotrópico T humano tipo 1 (HTLV1), que puede tener múltiples manifestaciones sistémicas, con progresión a nivel neurológico y cutáneo. Se presenta el caso de un paciente masculino con paraparesia espástica tropical, con HTLV-1 positivo, en el curso de una dermatitis infectiva, confirmada por histología.
Vonatnevek Magyarországon
Authors: Perger Imre
Published: April 2024

The study outlines the development of giving names to means of transport and describes the motivations behind the naming. It analyses in detail the development of train names. On the basis of an almost complete list of train names in Hungary, it examines domestic and international train names separately. The names discussed are divided into main groups and subgroups. The paper describes the characteristics of “good” and “bad” train names and outlines spelling and pronunciation problems. It also offers insight into informal train names and describes the background of the name giving. In addition to domestic examples, it also provides insight into the naming principles of railway companies in neighbouring countries. The paper concludes that naming practices in almost all countries give priority to geographical names (country, part of country, region, mountain, water). In addition, the names of famous people, historical figures, saints, artists (painters, sculptors, composers, writers, performers) have also been included in railway timetables, as have the names of landmarks (buildings, natural features), characters from novels and fairy tales. Latin names have also been given a prominent role in train names. The study also outlines the possibilities for further developments in the practice of naming trains.
Csoportnevek a Legere Irodalmi Versenyen
Authors: N. Tóth Anikó , Petres Csizmadia Gabriella
Published: April 2024

The paper presents the motives of the team names of the Legere Literary Competition for secondary school pupils at the University of Constantine the Philosopher in Nitra. The research, conducted over 11 years, used a questionnaire survey and the interview method to examine the 258-item descriptive group name data. Apart from a handful of names with unknown motivations, the corpus can be divided into two broad categories based on the motivation for naming: one broad category is made up of team names related to the spirit and theme of the competition, and the other category is made up of team names related to the individual competitors. In addition to a detailed description of the two categories, their subdivision, classification and illustration with examples, the paper also notes the diversity of naming methods and the linguistic and visual playfulness and humour of the team names.
Karakteristik dan Ukuran Tonsil Pasien Tonsilektomi di Instalasi Bedah Sentral Rumah Sakit Umum Provinsi NTB Bulan Juli Tahun 2019
Authors: Eka Arie Yuliyani  , Hamsu Kadriyan  , Didit Yudhanto  , Gusti Ayu Trisna A  , AA  Ayu Niti Wedayani  , Lalu Muhamad Abiyyu Ghaffar  , Fitriatulnisa
Published: April 2024

Latar Belakang: Tonsilitis kronis secara umum diartikan sebagai infeksi atau inflamasi pada tonsil palatina yang menetap. Pembesaran tonsil dapat menyebabkan beberapa komplikasi yang dapat menjadi indikasi dilakukanya operasi tonsilektomi. Tujuan dari penelitian ini adalah untuk mengetahui karakteristik dan ukuran tonsil pasien tonsikeltomi di Instalasi Bedah Sentral Rumah Sakit Umum Provinsi Nusa Tenggara Barat bulan Juli tahun 2019.Metode: Penelitian ini merupakan penelitian deskriptif retrospektif, dengan teknik consecutive sampling, menggunakan data sekunder pasien yang telah ada di RSUD Provinsi NTB bulan Juli 2019 kemudian di analisis dan disajikan dalam bentuk tabel dan narasi. Didapatkan 21 pasien yang menjalani tonsilektomi di IBS RSUP NTB selama bulan Juli 2019.Hasil: Distribusi berdasarkan tingkat umur nampak bahwa penderita tonsilektomi, sebagian besar adalah tergolong anak-anak yang berkisar pada umur 5-10 tahun. Berdasarkan jenis kelamin yang terbanyak adalah perempuan sebanyak 11 orang (52,4%). Penderita yang menjalani tonsilektomi lebih banyak karena indikasi relatif sebesar 19 pasien (90,5%) dengan keluhan utama terbanyak adalah nyeri pada tenggorok yaitu 12 orang (57,2%). Penderita tonsilitis kronis paling banyak mengalami pembesaran tonsil dengan ukuran tonsil T3-T3 yaitu 13 orang (61.9%).Simpulan: Dominasi indikasi melakukan tonsilektomi adalah indikasi relatif, yaitu keluhan yang berulang. Pasien yang menjalani operasi tonsilektomi paling banyak mengalami pembesaran ukuran tonsil T3/T3 dengan insiden tonsilektomi yang tinggi pada kelompok umur 5-10 tahun.
Karakteristik Pasien pada Pemeriksaan Elektroneurografi di Rumah Sakit Universitas Mataram Provinsi Nusa Tenggara Barat Periode Januari 2020 hingga Desember 2020
Authors: Muhammad Ghalvan Sahidu  , Ilsa Hunaifi  , Herpan Syafii Harahap  , Decky Aditya  Zulkarnaen
Published: April 2024

Latar Belakang: Pemeriksaan ENMG (Elektroneuromiografi) adalah pemeriksaan yang sangat berguna untuk menegakkan diagnosis penyakit sistem saraf perifer. Pemeriksaan ini merupakan kombinasi antara pemeriksaan elektroneurografi (ENG) dan elektromiografi (EMG). Elektroneurografi (ENG) disebut juga sebagai pemeriksaan konduksi saraf, yang mencakup pemeriksaan kecepatan hantar saraf (KHS) motoris, sensoris dan respon lambat. Abnormalitas dari KHS dan cetus potensial (evoked potentials) dapat mengungkapkan patofisiologi yang mendasari gangguan saraf tepi. Dengan pemeriksaan klinis yang baik, pemeriksaan ENMG akan membantu mempersempit diagnosis banding yang ada. Pemeriksaan ini membantu menentukan diagnosis topis, patologis dan prognosis kelainan susunan saraf tepi.Metode: Jenis penelitian ini adalah studi deskriptif observasional dari rekam medik pasien untuk mengetahui profil dan hasil pemeriksaan pasien yang menjalani pemeriksaan elektroneurografi di Poli rawat jalan Rumah Sakit Universitas Mataram. Pengambilan sampel berupa data rekam medis dari 1 Januari 2020 – 31 Desember 2020 dengan jumlah sampel 40 orang. Data hasil penelitian akan dimasukan dan disajikan dalam tabel dan gambar. Kemudian tabel dan gambar tersebut akan dianalisis.Hasil: Pasien sebagai subjek penelitian terbanyak adalah Laki-laki sebanyak 27 orang (67.5%). Pasien yang memiliki berat badan terbanyak dengan rentang berat badan 51-100 kg sebanyak 30 orang (75%). Untuk tinggi badan terbanyak dari sampel adalah di rentang 150-200 cm dengan jumlah 34 orang (85%). Pasien terbanyak adalah dengan keluhan non-trauma sebanyak 34 orang (85%). Jumlah pasien yang terbanyak adalah polineuropati dengan jumlah sebanyak 22 orang (55%).Kesimpulan: Dari penelitian ini didapatkan pasien yang melakukan pemeriksaan elektroneurografi pada Poli Saraf Universitas Mataram memiliki karakteristik dan hasil pemeriksaan yang sangat bervariasi.
Nefrolitiasis pada Pasien Nephroptosis
Authors: Made Ari Samudera  , Akhada Maulana
Published: April 2024

Nephroptosis atau ren mobilis didefinisikan sebagai suatu kondisi dimana terjadi penurunan posisi anatomis ginjal lebih dari 2 corpus vertebrae (> 5 cm) saat posisi berubah dari berbaring ke berdiri. Kasus ini lebih sering mengenai wanita dan pada ginjal sebelah kanan, meskipun terdapat 10 % kasus pada ginjal kiri, dan 20 % pada ginjal bilateral. Nyeri nephroptosis merupakan gejala yang sering dialami pasien ren mobilis. Komplikasi ren mobilis adalah hipertensi, dan bisa juga menyebabkan terbentuknya nefrolitiasis (batu ginjal). Tatalaksana ren mobilis adalah nefropeksi atau bila ginjal rusak maka dilakukan nefrektomi. Pada laporan kasus ini dilaporkan pasien wanita usia 75 tahun dengan ren mobilis dengan batu ginjal kanan. Keluhan pasien adalah nyeri pada perut bagian bawah namun membaik saat berbaring. Pasien memiliki riwayat hipertensi. Pada CT scan abdomen didapatkan batu pada ginjal kanan dan hidronefrosis berat kanan, dan ginjal tampak berlokasi di daerah pelvis. Kemudian dilakukan nefrektomi kanan karena parenkim ginjal sudah sangat tipis dan rusak. Selama dan pasca pembedahan, kondisi pasien stabil dan pasien dipulangkan pada hari ketiga pasca pembedahan.
PENGARUH INTENSITAS KEBISINGAN TERHADAP NILAI AMBANG DENGAR PADA PEKERJA DI PT. X DAN PT. Y PALU
Authors: Putri Zalsabilla Intan , Nayoan Christin Rony
Published: April 2024

Latar belakang:kebisingan adalah suatu gangguan lingkungan yang diartikan sebagai suara yang mengganggu di suatu tempat atau waktu yang tidak sesuai. Paparan kebisingan yang tinggi di tempat kerja dapat mengakibatkan timbulnya beberapa gangguan yaitu gangguan pendengaran seperti ketulian. Pada tahun 2014 gangguan pendengaran akibat bising di Indonesia termasuk yang tertinggi di Asia Tenggara yaitu sekitar 36 juta orang atau 16,8% dari total populasi. Diperkirakan 18.000 orang menderita Noise Induced Hearing Lost (NIHL) yang akibat pekerjaan.
Metode :Jenis penelitian observasional analitik dengan metode cross sectional. Sampel pada penelitian berjumlah 30 yang berasal dari 2 perusahaan yang berbeda. Dilakukannya pengukurkan intensitas kebisingan di kedua tempat kerja menggunakan sound level meter dan dilakukan pengukuran nilai ambang dengar pekerja menggunakan audiometer.
Hasil:Hasil penelitian ini pada kedua tempat penelitian, intensitas kebisingan yang melebihi ambang batas yang diperbolehkan oleh kepmenaker 2011, yaitu >85 dB. Hasil analisis intensitas kebisingan dan nilai ambang dengar pada telinga kanan menunjukan koefisienkorelasi 0,062 arah positif (+) dan p-value 0,746. Sedangkan Hasil analisis data intensitas kebisingan dan nilai ambang dengar pada telinga kiri menunjukan koefisien korelasi -0,034 arah negatif (-) dan p-value 0,856.
Kesimpulan: pada penelitian ini didapatkan nilai ambang dengar >85 dB, serta hubungan antara kedua variabel yaitu intensitas kebisingan dan nilai ambang dnegar yang tidak memiliki hubungan yang signifikan.
Uji Efek Protektif Madu Hutan (Apis dorsata) Terhadap Ketinggian Vili dan Kedalaman Kripta Duodenum Tikus Jantan Galur Wistar yang Diberi Pajanan Aspirin
Authors: Rahayu Anisa Ulwi , Ilmiawan Muhammad Inâ€™am , Hermawati Ery
Published: April 2024

Latar belakang:Ulkus peptikum merupakan efek samping utama dari aspirin yang merupakan obat dari golongan NSAIDs. Madu mengandung flavonoid yang memiliki sifat antioksidan yang dapat mencegah dan menghilangkan kerusakan oksidatif. Flavonoid dapat mempertahankan vili dari kerusakan struktur duodenum.
Metode:Penelitian ini merupakan penelitian eksperimental dengan desain post test only-control group. Sampel merupakan bahan biologi tersimpan berupa preparat histologi duodenum tikus yang telah mendapat perlakuan dan dibagi menjadi 5 kelompok: kelompok kontrol normal (KN), kelompok perlakuan I (KP1) (aspirin 400mg/kgBB + madu 1,55ml/kgBB), kelompok perlakuan II (KP2) (aspirin 400mg/kgBB + madu 3,1 ml/kgBB), kontrol positif (K+) (sukralfat 4 ml/kgBB), dan kelompok kontrol negatif (K-) (aspirin 400mg/kgBB). Variabel pada penelitian ini adalah ketinggian vili, kedalaman kripta, dan rasio vili:kripta duodenum, diamati dengan perbesaran lensa objektif 10x. Data dianalisa dengan menggunakan uji ANOVA dan post-hoc test LSD, serta uji Kruskal-Wallis dengan post-hoc test Mann-Whitney.
Hasil:1) Kelompok tikus yang diberi madu hutan dengan dosis 1,55 ml/kgBB, 3,1 ml/kgBB, dan aspirin memiliki vili yang lebih tinggi dibandingkan dengan kelompok tikus yang hanya diberi aspirin. 2) Kelompok tikus yang diberi madu hutan dengan dosis 1,55 ml/kgBB, 3,1 ml/kgBB, dan aspirin memiliki kedalaman kripta yang lebih baik dibandingkan dengan kelompok tikus yang hanya diberi aspirin. 3) Kelompok tikus yang diberi madu hutan dengan dosis 1,55 ml/kgBB, 3,1 ml/kgBB, dan aspirin memiliki rasio yang lebih baik dibandingkan dengan rasio tinggi vili : kripta duodenum tikus yang hanya diberi aspirin.
Kesimpulan:Pemberian madu hutan (Apis dorsata) memberikan efek protektif terhadap duodenum tikus yang diberi pajanan aspirin.
AN UNUSUAL CASE OF PATIENT WITH DILATED CARDIOMYOPATHY SECONDARY TO HYPOTHYROIDISM: A CASE REPORT
Authors: Pramana Ketut Angga Aditya Putra , Pintaningrum Yusra
Published: April 2024

Background:Alteration in thyroid hormone may affect on the cardiovascular system because the heart is very sensitive to an alteration of thyroid hormone. Alteration in thyroid hormone has been known to cause the changes in cardiac structure and function, such as thedevelopment of dilated cardiomyopathy which is a very rare manifestation of hypothyroidism.
Case Illustration:A 26-year-old woman came to a cardiology clinic with a chief complaint of fatigue and breathlesness. On physical examination are unremarkable. On clinical laboratory examinations showed elevated TSH serum levels and decreased FT4 serum levels. On echocardiography, the patient had moderate mitral regurgitation, mild tricuspid regurgitation, all chamber dilatation, and abnormal left ventricular systolic function with ejection fraction 26.9%. The treatment of this patient are levothyroxine 50ug/day, furosemide 40 mg, spironolactone 25 mg, bisoprolol 2.5 mg, ramipril 1.25 mg, and acetylsalicylic acid 80 mg all in once daily.
Discussion:Dilated cardiomyopathy is characterized by enlargement of the ventricular chamber with impaired systolic function. Hypothyroidism is associated with decreased cardiac contractility and decreased cardiac output because of the genomic effect of thyroid hormone to the cardiovascular system is involved in the regulation of mRNA transcription of genes associated with the contractile system.
Conclusions:Hyperthyroidism is often cause dilated cardiomyopathy, but in this case, hypothyroidism also can cause dilated cardiomyopathy. Early diagnosis and management of hypothyroidism are very important to restore the cardiac function.
OSTEOSARCOMA IN CHILDREN: A CASE REPORT
Authors: Purnaning Dyah , John Sonya Ananda Ellya
Published: April 2024

Osteosarkoma adalah kanker yang berasal dari sel mesenkim dan merupakan keganasan tulang primer yang paling umum terjadi pada anak-anak dan remaja. Pasien dengan osteosarkoma sering memiliki keluhan yang tidak spesifik, termasuk nyeri pada daerah yang terkena. Pada populasi anak-anak, keluhan nyeri dan bengkak pada tahap awal ini sering mengalami kekeliruan dan dikaitkan dengan trauma. Hal ini mengakibatkan rata-rata onset sejala hingga penegakkan diagnosis berlangsung selama sekitar 3-4 bulan. Apabila tumor melibatkan area disekitar sendi (distal femur dan proksimal tibia), nyeri dapat diperburuk oleh berat tubuh sehingga pasien akan menjadi kesulitan untuk berjalan. Diagnosis osteosarkoma paling baik dilakukan melalui pendekatan multidisiplin yang komprehensif. Salah satu pemeriksaan penunjang yang terjangkau dan cukup efektif untuk menegakan diagnosis adalah rontgen atau X-ray. Pada pemeriksaan X-ray, dapat terlihat ukuran dan lokasi tumor serta tingkat kerusakan tulang yang disebabkan oleh tumor tersebut. Pemeriksaan ini juga memvisualisasikan reaksi periosteal dan segitiga Codman, yang merupakan gambaran khas pada Osteosarkoma. Tatalaksana osteosarkoma terdiri atas tindakan pembedahan dan terapi neoadjuvan. Pada kasus ditunjukkan gambaran osteosarkoma pada anak laki-laki berusia 15 tahun. Diagnosa baru ditegakkan 7 bulan pasca onset awal penyakit pasien. Pada pasien ini dilakukan tindakan pembedahan yaitu amputasi transfemoral dan penanganan klinis pasien termasuk kondisi malnutrisi yang dialami oleh pasien.
KORELASI ANTARA EKSPRESI GLUT4 NEURON HIPOKAMPUS DAN TRAVEL TIME TIKUS MODEL DIABETES TIPE 2 PADA PEMERIKSAAN MORRIS WATER MAZE DENGAN WAKTU PENGAMATAN YANG BERBEDA
Authors: Hifdzil Haq Muliyana  , Anak Agung Ayu Niti Wedayani  , Herpan Syafii Harahap
Published: April 2024

Latar Belakang: Diabetes adalah penyakit metabolik kronis yang dapat mengganggu fungsi organ tubuh terutama otak. Kejadian diabetes di Indonesia pada usia 15 tahun ke atas meningkat dua kali lipat di tahun 2013 dibandingkan tahun 2007. Pada diabetes melitus menunjukkan terdapat perubahan kadar protein GLUT4 di otak. Perubahan ini diduga memiliki peran penting dalam menjalankan fungsi kognitif. Tujuan penelitian ini untuk mengetahui korelasi yang bermakna antara ekspresi GLUT4 neuron hipokampus dan travel time tikus model diabetes tipe 2 dengan pemeriksaan morris water maze pada waktu pengamatan yang berbeda. Penelitian eksperimental ini menggunakan 16 ekor tikus putih (Rattus novergicus) yang dibagi secara acak menjadi 4 kelompok yaitu 2 kelompok kontrol (A0 dan A1), dan 2 kelompok perlakuan (B0 dan B1). Tikus dilatih fungsi kognitifnya dengan morris water maze selama 4 hari. Kelompok perlakuan diinduksi diabetes dengan nikotinamid 110 mg/kgBB dan streptozotocin 70 mg/kgBB dosis tunggal secara intraperitoneal. Data dianalisis menggunakan uji statistik t-test, Pearson dan Spearman. Rerata ekspresi GLUT4 kelompok tikus diabetik signifikan lebih tinggi pada pengamatan hari ke-14. Rerata ekspresi GLUT4 signifikan lebih tinggi pada kelompok diabetik dibandingkan kelompok kontrol pada pengamatan hari ke-14 (p<0,05). Rerata travel time tidak menunjukkan perbedaan yang signifikan pada semua pengamatan (p>0,05). Hasil uji korelasi tidak menunjukkan nilai yang signifikan pada pengamatan hari ke-0 maupun hari ke-14 (p>0,05). Tidak terdapat korelasi bermakna antara ekspresi GLUT4 neuron hipokampus dan travel time tikus model diabetes tipe 2 dengan pemeriksaan morris water maze pada waktu pengamatan hari ke-0 dan ke-14.
GAMBARAN HASIL DARAH RUTIN PENDERITA LEUKEMIA MIELOID KRONIS DI RUMAH SAKIT UMUM DAERAH PROVINSI NUSA TENGGARA BARAT
Authors: Adhika Tri Putra Sugiharta  , Joko Anggoro
Published: April 2024

Latar belakang: Leukemia Mieloid Kronik (LMK) adalah salah satu keganasan hematologi yang ditandai dengan peningkatan dan pertumbuhan yang tak terkendali dari sel myeloid pada sumsum tulang. Keganasan ini disebabkan oleh translokasi resiprokal antara kromosom 9 dan 22 yang menghasilkan kromosom Philadelphia yang menghasilkan gen gabungan yaitu BCR-ABL yang. Gen gabungan ini menghasilkan 210-kd protein yang berhubungan dengan aktivitas tirosin kinase, gen ini mengakibatkan proliferasi dari granulosit matang (neutrofil, eosinophil, dan basophil) dan prekursornya. Oleh karena pentingnya diagnosis dan sebaran penyakit ini khususnya di NTB, peneliti ingin mengetahui gambaran darah rutin sebagai salah satu metode diagnosis penyakit LMK terutama di RSUDP NTB. Metode: Penelitian ini menggunakan metode deskriptif dengan metode pendekatan potong lintang. Penelitian dilakukan mulai bulan Januari 2020 sampai dengan Februari 2020. Penelitian ini menggunakan data catatan rekam medis pada pasien LMK yang dirawat di Rumah Sakit Umum Daerah Provinsi Nusa Tenggara Barat dari bulan Desember 2016 sampai Januari 2020. Total ada 26 pasien LMK yang menjadi responden dalam peneltian ini. Hasil: Pada penelitian ini, terdapat 26 pasien dengan rasio perbandingan jumlah laki-laki dan perempuan sebanyak 61,5% dan 38,5%. Kelompok usia terbanyak yang mengalami LMK adalah 41-50 tahun (23,1%) dengan rerata usia 44 tahun. Penderita LMK rata-rata mengalami anemia sedang (30,8%), trombositosis (42,3%) dan leukositosis (92,3%). Kesimpulan: Penderita LMK di Rumah Sakit Umum Provinsi Nusa Tenggara Barat paling banyak adalah laki-laki, dengan rerata terjadi pada usia pertengahan, mengalami anemia sedang, peningkatan trombosit dan peningkatan leukosit.
A IMPORTÂNCIA DA PSICOLOGIA JURÍDICA
Authors: Costa Wania Paula da , Pedrosa Vanessa da Silva , Silva Alana Cecilia Augusto da , Ribeiro Jenifer Maria da Silva , Jerônimo Alex de Souza , Oliveira Yara Gomes Duarte de , Vale Aléxa Rodrigues do
Published: April 2024

O presente artigo tem por objetivo discutir a importância da psicologia jurídica, a qual é o
campo da psicologia que adiciona os profissionais que se dedicam à interação entre a psicologia e o
direito. O direito trata da compartição de liberdade e a psicologia, de forma geral, ocupa-se com o
comportamento humano e seus processos mentais, sendo a principal função neste âmbito da justiça,
assistencial em questões relativas à saúde mental dos envolvidos em um processo. Apesar de ainda ser
muito recente, a psicologia jurídica, é uma das partes da psicologia que obteve maior ascensão nos últimos
anos. Para tanto, a pesquisa é bibliográfica, apresenta natureza exploratória, utilizando-se de bibliografias,
legislação e documentários existentes. O estudo mostra a importância desta ciência no judiciário. Com a
pesquisa realizada concluiu-se que é preciso aperfeiçoar a área e os métodos existentes, incentivando os
profissionais e promovendo ainda mais a credibilidade da psicologia no judiciário brasileiro.
A REDENÇÃO DE CAM: IMAGEM-DESPERTADOR E IDEOLOGIA DO BRANQUEAMENTO
Authors: Almeida Maureci Moreira de
Published: April 2024

A ideologia do branqueamento é uma das principais características do racismo no Brasil, e está na estrutura das relações sociais, atrelado basicamente ao aspecto referencial estético-fenotípico dos brasileiros. As reflexões tecidas neste artigo estão focadas na ideologia do branqueamento, e para tal, nos deteremos na obra “A redenção de Cam” (1895), do artista plástico espanhol Modesto Brocos (1852-1936). Tal obra foi amplamente utilizada por jornalistas, intelectuais e ideólogos do racismo no final do século XIX e início século XX, como forma de propagandear a necessidade de mudança racial da sociedade brasileira que consideravam demasiadamente negra. Segundo suas crenças racistas, o Brasil não avançava para um patamar elevado de civilidade e desenvolvimento econômico por ser atrasado justamente pela mistura de “raças”. Para compreender a influência da obra de Modesto Brocos ao propagandear a ideologia do branqueamento, vamos abordar topicamente alguns aspectos teóricos da imagem como forma de repercutir determinadas formas de pensar e conceber o Brasil. Especial atenção será dada à noção de imagem-despertador, seguindo as teorias de Rafael Mangana (2018), cujas ideias ajudam a compreender os impactos da obra de Brocos e sua “A Redenção de Cam”.
O RACISMO ESTRUTURAL NA DERMATOLOGIA BRASILEIRA
Authors: Polegato Giovanna Alimenti , Gonzaga Alvaro Luiz Travassos de Azevedo , Aguiar Gisele Pereira
Published: April 2024

O presente artigo busca escancarar o racismo estrutural na dermatologia brasileira. Realizou-se uma análise histórica para que se compreenda o racismo, no âmbito da dermatologia, como um processo histórico, em que as características físicas de pessoas de pele branca são valorizadas, de forma que se eleva o estudo das particularidades da pele branca na dermatologia brasileira. Observa-se que tal estratégia faz parte de uma ferramenta de eugenia e de supremacia branca, que faz com que se despreze o estudo das particularidades da pele negra na área da dermatologia brasileira. O direito, como ferramenta antidiscriminatória, pode ser utilizado para introduzir, na Lei nº 8.080/90, a Lei Orgânica da Saúde, um protocolo de tratamento médico que inclua o estudo das particularidades da pele negra. É igualmente importante que o Ministério da Educação (MEC), em controle de qualidade do curso de medicina, inclua a abordagem de protocolos de tratamento da pele negra na disciplina de dermatologia.
ECOLOGIA POLÍTICA INTERNACIONAL DA ÁGUA E ESTUDO DE CASO: LAGOA MIRIM
Authors: Brito Antônio Guimarães , Pereira Brum Renato Cruz
Published: April 2024

" O tema da água representa o maior desafio da ecologia planetária. A escassez da água, a má distribuição, a desertificação, a mercantilização, tudo afeta e determina a fome mundial, a mortalidade dos mais pobres, as doenças mais endêmicas, agricultura, saneamento, enfim, a base dos direitos mais fundamentais a dignidade humana. As doenças mais fatais que atingem os mais pobres estão relacionadas com a qualidade da água e as condições sanitárias. Também a agricultura, os alimentos precisam essencialmente da água, e a causa de maior consumo da água, principalmente aquilo que passou a ser chamado de agronegócio. Sem água não há agricultura e alimentos. Por outro lado existe uma falsa pauta verde disfarçada, o tal capitalismo verde, a percepção e a lógica que reproduz o caráter utilitarista, elitista reduzindo o meio ambiente em recursos econômicos. Essa perspectiva é a mesma da exploração do trabalhador, do racisno, da misoginia, da destruição dos rios, das florestas, dos povos indígenas. Todo esse processo está interligado , capital, pobreza, genocidio o patriarcado e as politicas de agressão ao ser humano e a natureza. Esse livro é uma reflexão. Da complexidade e do ecologismo elitista. Também um estudo sobre a Lagoa mirim. Fronteira liquida e binacional entre Brasil e Uruguai. Local de imensa importância ecológico e a biodiversidade. Água é fundamental, direto igual de todos, não podendo ser objeto do capital. Água para toda a humanidade, água potável. Água é a essência do meio ambiente, os rios são o sangue da natureza. Neste sentido, a perspectiva do ecossocialismo, ecofeminismo, ecologia politica crítica, ecodecolonialidade, expressam uma consciência ecológica mais próxima da esperança de um mundo possível, que liberte o ser humano do sofrimento e possibilite novas relações com o meio ambiente e todos os seres.
A didactic engineering for the study of the Padovan’s combinatory model
Authors: Vieira Renata Passos Machado , Alves Francisco Regis Vieira , Catarino Paula Maria Machado Cruz
Published: April 2024

Considering the content of history of mathematics textbooks, it’s evident that their emphasis is primarily on the illustrative aspects of recurring numerical sequences, with a particular focus on the Fibonacci sequence. Unfortunately, this limited approach results in the neglect of other sequences akin to the Fibonacci numbers, thus rendering the subject challenging for teaching purposes. This study aims to address this gap by offering a concise exploration of the combinatorial aspects of the Padovan numbers, specifically through the concept of a board as initially examined by mathematicians. In line with the research methodology of didactic engineering and the teaching theory of the theory of didactic situations, two problem situations have been developed, centered on the Padovan combinatorial model, thereby contributing to the enrichment of mathematical education within initial teacher training programs. Within this framework, various strategies are introduced that rely on visualization and counting, with the objective of illustrating specific mathematical identities suitable for potential classroom applications.
Application of seismic methods for determining the depth of the rock mass damage zone around the excavation profile by blasting
Authors: Ekrem Bektašević  , Hrvoje Antičević  , Kemal Gutić  , Denijal Sikira
Published: April 2024

Research and determination of the blasting damage zone around the profile of tunnels or underground structures is a platform that would serve to confirm or correct blasting parameters and underground assemblies, that is, geotechnical and main tunnel projects. From the obtained research, the stability of the excavation profile, as well as the safety risk for equipment and personnel on the construction site, would be better understood. Considering the importance of the size of the damage zone of the rock mass in terms of its influence on stability, the amount of primary support elements required to achieve the stability of the excavated space, and the additional costs of stabilization of the excavation and the safety of people and equipment, the aforementioned problem was investigated and processed for specific cases and for the rock mass characteristic for the location in question. From the described research, the change in the elastic characteristics of the rock mass and the depth of the damage zone around the tunnel excavation profile were measured and calculated.
Administration of ethanol extract of galangal (Alpinia Galanga) on histopathology of male mouse (Mus musculus) lungs exposed to lead acetate
Authors: Alifya Putri  , Epy Muhammad Luqman  , Eka Pramyrtha Hestianah  , Budiarto Budiarto
Published: April 2024

Objective: This research aims to assess the preventive effect of ethanol extract of red galangal (Alpinia Galanga) on type I pneumocyte cell necrosis and proliferation of type II pulmonary pneumocytes in male mice (Mus musculus) exposed to lead acetate-induced damage. Method: A total of 25 male mice aged 2.5-3 months and weighing 25-30 g were divided into five groups. The negative control group (K-) received oral water without lead acetate exposure, while the positive control group (K+) received 20 mg/kg BW of lead acetate. The treatment groups P1, P2, and P3 were exposed to lead acetate at a dose of 20 mg/kg BW/day and received red galangal extract at doses of 200 mg/kg BW, 400 mg/kg BW, and 800 mg/kg BW, respectively. All treatment groups were administered lead and ethanol extract of galangal orally from days 4 to 24 at a rate of 0.2 ml/head. Results: The Mann-Whitney U statistical test revealed a significant increase in type I pneumocyte cell necrosis and type II pneumocyte cell proliferation in the lungs of male mice (Mus musculus) exposed to lead acetate (p<0.05). Administration of ethanol extract of galangal after exposure to lead acetate significantly reduced type I pneumocyte cell necrosis and type II pneumocyte cell proliferation (p<0.05). The highest dose of galangal ethanol extract, 800 mg/kg BW, showed a significant decrease in type II pneumocyte cell proliferation (p<0.05). Conclusion: This study concludes that red galangal extract has a preventive effect in reducing the damage to type I and type II pneumocytes in the lungs of male mice (Mus musculus) exposed to lead acetate.
Effect of line length on the fault current due to line to ground fault in transmission line using MATLAB Simulink
Authors: Kabir Chakraborty  , Sanchari De  , Purnima Nama
Published: April 2024

Today, electrical power is a necessity for many aspects of daily living, including works in homes, businesses, industries, and agriculture. This article is created to ensure that the electrical power needed by these sectors is maintained. In an electrical system, numerous faults can arise owing to line-to-ground (L-G), line-to-line (L-L), and three lines (L-L-L). This study addresses the analysis of fault current under line-to-ground (L-G) and how it varies with the fault position. MATLAB Simulink has been utilized in this work to demonstrate how fault current depends on the line length of transmission system during L-G faults.
A review on tablet binders as a pharmaceutical excipient
Authors: Rajeshwari Gokul Khairnar  , Ashwini Ramdas Darade  , Rupali Rajesh Tasgaonkar
Published: April 2024

The tablet formulation contains binders that increase the inter-particulate bond power inside the tablet. Research and progress of novel accessories remains a priority for potential use as a binder in formulations tablet. Tablet binder or binding agent are the substances that are added either dry or in liquid form during wet granulation to form granules or to promote cohesive compacts for directly compressed tablets. E.g., starch, pregelatinized starch, PEG, sorbitol, and HPMC, etc. Tablet Binder and disintegrants have the opposite used in an oral solid formulation. Binder delay tablet disintegration while disintegrant increase tablet disintegration. They play a vital role in making sure pellets or granules and tablets remain in shape until they reach their target by holding all ingredients (API and Excipients) together in any solid dosage form. Selecting the correct binder is critical to maintaining the integrity of the tablet. Natural binders such as various starches, Gums, mucus and dried fruits, among other things, have the ability to bind. Features such as Natural polymers, fillers, and disintegrants are also safe more economical than synthetic polymers.
Dampak Citra Merek, Iklan, dan Kualitas Produk Terhadap Minat Beli Konsumen Pada Produk Kopi Kapal Api di Surabaya
Authors: Alfiah Nofiana  , Aridha Prassetya  , Harsono Teguh  , Diana Zuhro  , Sutini Sutini
Published: April 2024

Producers of packaged instant coffee have to compete fiercely to get consumers' attention, because the many types of packaged instant coffee on offer make consumers increasingly free to make their choices. Kapal Api Coffee producers need to evaluate marketing policies in the form of brand image, advertising and product quality and their influence on consumer demand to buy, so that they are expected to be able to innovate to increase their sales. This research aims to find out whether there is an influence on brand image, advertising and product quality on consumer buying interest in Kapal Api Coffee products in Surabaya. This research approach uses quantitative research. The data used are respondents' answers from distributing questionnaires. Data analysis techniques use multiple linear regression analysis, F test, and t test. Based on the research results, it is known that brand image, advertising and product quality simultaneously influence consumer buying interest in Kapal Api Coffee products, because the F test results show the calculated F value is greater than F table, namely 34.040 > 2.699. Brand image partially influences consumer buying interest in Kapal Api Coffee products, this is proven by the t test which shows the calculated t value is greater than the t table, namely 4.569 > 1.985. Advertising partially influences consumer buying interest in Kapal Api Coffee products, this is proven by the t test which shows the calculated t value is greater than the t table, namely 2.190 > 1.985. Product quality partially influences consumer buying interest in Kapal Api Coffee products, this is proven by the t test which shows the calculated t value is greater than the t table, namely 3.531 > 1.985. Based on the research results, it is also known that brand image (X1) has a dominant influence on purchasing interest. This is proven by the t test where the calculated t value of brand image (X1) is greater than the calculated t value of the advertising variables (X2) and product quality (X3), namely 4.569.
Methodology for ensuring the functional stability of aircraft integrated modular avionics complex
Authors: Калашник Г. А. , Калашник-Рибалко М. А.
Published: April 2024

The article presents the methodology of ensuring the functional stability of aircraft avionics complexes under the influence of failure and destabilizing factors. It is based on the procedure of maintaining valid knowledge bases of individual modules of the avionics complex through the organization of dynamic verification of such knowledge bases during their application on the principle of the probabilistic diagnostic core with system recovery without significant restructuring of verification means. The results of calculations of indicators of functional stability of the integrated avionics complex of the D-42 aircraft are presented in the article. To increase the efficiency of the integrated avionics complex under conditions of destabilizing influences, the optimal structure of the avionics complex of the D-42 aircraft was synthesized according to the criterion of the maximum indicator of functional stability with the limitation of the cost of construction the system. In the calculations, an increase in the generalized indicator of functional stability was achieved in comparison with the original structure by 30.8 % (from 294.2 to 384.9) for the given conditional cost 20,000 с.u. It is the most acceptable according to the generalized indicator of functional stability, as a criterion of preference under the specified cost limitations and taking into account the limitations of other parameters of the effective operation of the complex. Increasing the functional stability of the avionics complex according to the presented methodology will allow timely detection of implicit failures and parry their consequences. Based on the results of these studies there is a possibility: substantiation of requirements for the structures of avionics complexes to be designed, solving the problem of synthesis of optimal structure on the criterion of maximum functional stability with limited construction costs, as well as a reasonable increase in the structure of the distributed system of the aircraft avionics complex.
Аналіз методів формування раціонального складу колективу різнорідних безпілотних літальних апаратів для виконання бойових завдань
Authors: Квіткін К. П. , Тристан А. В. , Сізон Д. О.
Published: April 2024

Представлено аналіз методів визначення раціонального складу колективу безпілотних літальних апаратів (БпЛА) для виконання бойових завдань. Розглянуто зміст методу аналогій, експертно-аналітичного методу, методу структуризації цілей та методу моделювання. Запропоновано математичний опис розглянутих методів, який допомагає визначити найкращий склад та врахувати необхідні показники для успішного виконання визначених завдань. Крім того, визначено основні переваги та недоліки розглянутих методів у подальшому практичному застосуванні.
Метод обробки матриць подій для ототожнення та фільтрування консолідованої інформації про повітряні об’єкти від різнорідних джерел
Authors: Самсонов В. С. , Сідченко С. О.
Published: April 2024

У статі розроблено метод обробки матриць подій, який дозволяє прийняти ґрунтовне рішення на ототожнення повітряних об’єктів. Метод складається з десяти етапів. На першому та другому етапах проводиться розподіл інформації про повітряну обстановку, яка надходить від різнорідних джерел, на компоненти. На третьому та четвертому етапах створюється двомірна матриця подій та поділяється на окремі блоки через визначені проміжки часу (проводиться стробування). На п’ятому етапі зі значень визначених характеристик повітряних об’єктів створюється діапазон їхніх значень з використанням відповідних коефіцієнтів. Шостий етап полягає у порівнянні діапазонів значень однакових характеристик між суміжними рядками (кортежами) матриці подій. За результатами порівнянь та підрахунку кількості циклів обчислень визначається належність двох кортежів до одного повітряного об’єкта. На сьомому та восьмому етапах приймається рішення та проводиться ототожнення повітряних об’єктів. Дев’ятий етап полягає у створенні усереднених значень характеристик повітряних об’єктів з однаковими маркерами та здійснюється злиття двох кортежів в один (консолідація інформації). Взаємне доповнення даних з двох кортежів приводить до збагачення інформацією новий, узагальнений кортеж. На десятому етапі проводиться розподіл кортежів за трьома напрямками (вихідна інформація для споживачів інформації, знищення кортежів, додаткове розширення діапазону значень розмитих характеристик та направлення кортежу на повторну обробку). Метод дозволяє виявити та відфільтровувати інформацію, яка дублюється, а також збагатити дані про повітряні об’єкти. Вихідну інформацію доцільно використовувати для забезпечення сховищ даних або баз даних.
Energy Box Simulator
Authors: Fitriyah Qoriatul , Sebayang Irma Sherina , Nugroho Berto Yusuf , Setyawan Albertus Agung Danatyo , Wahyudi Muhammad Prihadi Eko
Published: April 2024

This research is focused on making the trainer kit in the form of a device for measuring and calculating energy with an interactive practicum mode that is fun for students as part of the Thermodynamics course. This device will be equipped with a timer for measuring time, electrical mass measurement and a length calculator for measuring kinetic energy and potential energy using data on mass, velocity and height of an object. The data obtained from the measurement results will then be compared with the results of calculations on an application-based simulator in the visual basic .exe program.