bluuebunny/crossref_metadata_2025 huggingface dataset:
RIZHOME AND BAROCCO AS CULTURAL-ONTOLOGICAL FOUNDATION OF PHENOMENON OF INNOVATION
Authors: Ostrenko Serhei A.
Published: August 2016

The Purpose is to recover rhizome and barocco as cultural-ontological foundations of innovative process. Methodology is subjective analysis of conceptions ‘rhizome’ and ‘barocco’, thematization their presence in space of innovation carry out with using discoursing approaches’ of phenomenology, comparative, structuralism. Scientific Novelty. Rhizome has been opened as cultural-ontological foundation in its processes, problems, pre-predicative functions, totality, transcendence and principles of connection, diversity, cartography, re-traicng etc. It is showed that barocco with rhizome founds innovative process in some aspects: fold, binary, extension and texture. Conclusions. Rhizome as one of the foundations of innovation shows its non-line, statistic character that determines its creative potential and opens in two directions: from innovation to rhizome and on the contrary. In the first case when we have a deal with innovative characteristics as process, problems, pre-predicative, totality, transcendence. In the second case we have a deal with the principles which can carry out innovative activity: a) connection (unavoidable of freedom of researcher, and it correlates with the principle of epistemological anarchism ‘Anything goes’); b) inhomogeneity (maintenance of multiplicity of innovative decisions that correlates with postpositivistic principle of proliferation); c) multiplicity (attitude on principle refuse from tradition in innovative activity); d) a-signed break (non-line character of innovative processes); e) cartography (constructive character of innovations with possibility of variety of different senses); f) re-tracing (critical attitude to the past and probable results in the future). Barocco consist in specific of innovative activity on contemporary period and has some parameters: fold: innovative activity in conceptual and methodological aspects are carrying out as multiple folds, crossing of different sense fields: b) binary opposition ‘interior – exterior’: innovative activity is a point of crossing and break of spontaneous and determine processes; c) binary opposition ‘up – down’: innovative activity has non-line, topological character; d) extension: in innovative activity priority has process on ending; e) texture as sing of singular character of innovative process; f) paradigm underlines fundamental, whole, universal character of innovation.
PHILOSOPHY OF TECHNOLOGY OF JOSE ORTEGA Y GASSET
Authors: Tereshkun Oksana F.
Published: August 2016

The purpose of the article is to understand the philosophy of technology of José Ortega y Gasset. The task is to examine the works of José Ortega y Gasset, first, the origin and the main stages of technological development; secondly, the relationship of natural circumstances, humans and technology; third, the relationship of the inner world of man and technology; fourth, the relationship of the world of culture and their life projects with technology; fifthly, the interplay of modern technology and "human mass". Methodology. For performance of the tasks are applied comparative approach for analysis of historical stages of technological development, human behaviour and the animals on natural circumstances of life projects of bodhisattva, hidalgo and gentleman of the production technology. Using the functional approach has revealed the close, the inextricable link between the appearance and operation of equipment and the inner world of man, culture and lifestyle program that it implements. The elements of scientific novelty of our research is the isolation, structuring, analysis, synthesis and systematization of the main ideas of the philosophy of technology of José Ortega y Gasset. Conclusion. Summarizing the aforesaid, it should be noted that José Ortega y Gasset creates its philosophy of technology through specific synthesis of existentialism, marxism and the philosophy of life. His rational vitalism is the integration of various philosophical currents of the late XIX – early XX century. The issue of his philosophy of technology is extremely broad. The philosopher is not limited to the analysis technique. It thoroughly examines the issues of technology due to the existence of man, his inner world and life program, criticizes the idea of progress and technological determinism. As part of his research include issues such as communication technology and culture, orientation of technological development and its dependence on the type of culture and science.
TRANSFORMATION REFLEXES OF PRE-CHRISTIAN WORLDVIEW IN KIEVAN RUS LITERATURE
Authors: Stratonova Nataliia O.
Published: August 2016

The purpose of this article is to review the literature of Kievan Rus' in the light of interaction and mutual influence of Christian and pre-Christian worldviews; to open and show the character of the relations of pre-Christian and Christian religions; to reveal some aspects of these relationships in the literature of Kievan Rus in XI-XIII centuries. Methodology. Among the general scientific approaches in solving the problems that have been used was primarily theological and philosophical. This approach allowed us to explore and objectively analyze the tendency to reflect pre-Christian beliefs in the literature of Kievan Rus. As specially-scientific methods there were used historiosophical (philosophical understanding of historical events and processes), topical (selection and analysis of the basic conceptual directions of transformations), chronological (link historiographical tradition with a concrete historical reality) and the philosophical and hermeneutical (theological-philosophical interpretation of monuments). Scientific novelty. The work is theological and philosophical reflection analysis of pre-Christian ideas in literary monuments of Kievan Rus. For the first time takes into account the specifics of medieval imagination and poetry, studied the religious significance of the texts found their reflection in the pre-Christian beliefs and stated on their role in shaping the world Kievan Rus’ scribes, analyzed the specificity of interaction between Christian and pagan notions. Conclusions. In the process, the author comes to the conclusion that by denying the fact of paganism, separating itself along with other Orthodox nations from the "Latins" and "heretics", Rus claimed its identity through the adoption of Christianity. This process has had its impact on the internal development of the mythodogical consciousness of the people, has accelerated the emergence of the epic in his heroic cycles and Kiev, where it was easy, but dosed and originally instilled Christian ritual principles and values.Byzantine and Bulgarian literature’s circle passed to Russ ready and clear truth, and Rus scribes were the first who learnedit as a model for their life. It is practical, saint idea became the basis of Rus literacy. The apparent ease of assimilation of people outside of the Orthodox Church with the epic structure is not set to culture in general, the problem of conscious, long and organized opposition to the new faith and the old folk pagan wisdom, representatives of which remained "team change people's consciousness," because she folk wisdom in his epic the design principles adopted ritual orthodoxy.
Fetichismo e subjetividade feminina
Authors: Campos Denise Teles Freire
Published: August 2016

Em seu processo de subjetivação algumas mulheres parecem apresentar uma certa “dificuldade” em ter filhos. Assim, uma demanda incessante de ter um filho é apresentada à medicina (demanda insaciável, visto que ela não se dirige àquilo que exprime) e vem ocupar o lugar de objeto da falta. O jogo do Ter se substitui ao Ser, e permite a permanência dessas mulheres em uma posição de passagem, em uma estrutura fortemente marcada por uma vertente fetichista, que ocupa o lugar da demanda de amor dirigida à mãe. Contrariamente à posição freudiana, pela qual ter um filho permite a resolução final do Édipo, nosso material clínico revela que, nestes casos, o chamado “desejo de ter um filho” responde a uma recusa em subjetivar a falta, recusa em “se tornar mulher”, cuja manifestação é uma posição fetichizada.
Frigidez feminina e a dialética do amor, desejo e gozo
Authors: Grant Walkiria Helena
Published: August 2016

A frigidez feminina, diferentemente da impotência masculina, necessariamente não se faz sintoma. É no decorrer do trabalho analítico que ela pode assumir o estatuto de sofrimento para um sujeito. O que pode nos oferecer a psicanálise como parâmetros para pensarmos a(s) causa(s) da frigidez? Com Freud, retomaremos aspectos da célebre análise conduzida na princesa Marie-Bonaparte, que sofreu com sua frigidez. Com Lacan, destacaremos o manejo da relação transferencial para que a dialética do amor, desejo e gozo possa ter lugar no mundo psíquico daquela que ocupava a posição defensiva denominada frigidez.
Milk and açaí berry pulp improve sensorial acceptability of kefir-fermented milk beverage
Authors: NOGUEIRA Lara Kozlowski , AGUIAR-OLIVEIRA Elizama , KAMIMURA Eliana Setsuko , MALDONADO Rafael Resende
Published: August 2016

ABSTRACT Kefir grains are a symbiotic biomass (yeast and bacteria) commonly used to produce milk probiotic fermented beverages. The aim of this study was to produce a mixed beverage of whole milk and açaí (Euterpe oleracea) berry pulp fermented by two different kefir cultures: one specific for milk and one specific for sugared water, adapted to milk. Based on the fermentation yield, pH and sensory analysis, the culture adapted to milk obtained the best results in a composition (g 100 g-1) of 70 of whole milk and 30 of açaí berry pulp, at room temperature (~25°C), without agitation and fermented for 24 h. The results obtained by this formulation were an increase of 12% in the kefir biomass, 93% of fermentation yield, pH 5.10 and overall sensory acceptance of 7.05.
Oleanonic acid from Lippia lupulina (Verbenaceae) shows strong in vitro antileishmanial and antitrypanosomal activity
Authors: FUNARI Cristiano S. , ALMEIDA Letícia de , PASSALACQUA Thais G. , MARTINEZ Isabel , AMBRÓSIO Daniela L. , CICARELLI Regina Maria B. , SILVA Dulce Helena S. , GRAMINHA Márcia A. S.
Published: August 2016

ABSTRACT Leishmaniasis and Chagas disease affect millions of people in tropical and subtropical regions. Drugs used currently to treat such diseases often present undesirable side effects and low efficiency. The aim of this work was to identify extracts and isolated compounds from the genus Lippia with leishmanicidal and trypanocidal activity. Fifteen extracts from different plant parts of Lippia species with partially known chemical compositions, four partition fractions, six compounds and a mixture of four interconverting flavanones previously isolated from Lippia salviaefolia and Lippia lupulina were assayed in vitro towards epimastigote forms of Trypanosoma cruzi and promastigote forms of Leishmania amazonensis. The root extract of L. lupulina had potent activity against T. cruzi and L. amazonensis (IC50 of 20.0 and 54.5 µg mL-1, respectively). The triterpenoid oleanonic acid showed the strongest activity against these protozoans (IC50 of 18.5 and 29.9 µM, respectively). Our results indicate that Lippia plants and their derivatives deserve further investigation in the search for new antiprotozoal drugs, particularly for the treatment of leishmaniasis and Chagas disease.
Updated checklist of Hemerobiidae (Neuroptera) from Brazil and new distributional records in the Neotropical Region
Authors: LARA Rogéria Inês Rosa , PERIOTO Nelson Wanderley
Published: August 2016

ABSTRACT Hemerobiidae (Insecta, Neuroptera) is a cosmopolitan clade that comprises about 600 described species distributed into 26 genera. Since the publication of revisions to Hemerobius, Megalomus, Nusalala and Nomerobius, new records have been added in literature and taxonomic modifications have occurred at the genus level. The aim of this study was to update a checklist of Hemerobiidae species from Brazil and of specimens deposited at Coleção de Invertebrados do Instituto Nacional de Pesquisa da Amazônia (INPA), Manaus, Brazil; in order to summarize the geographical data of species in Brazilian states and in the Neotropical Region and to present new distributional data. The INPA collection holds 19 nominal species (55.2% of the all specimens identified at species level) of hemerobiids into eight genera and six subfamilies, mainly from the Neotropical Region; the remaining studied specimens were identified to the genus level. Megalomus marginatus is reported for the first time in Brazil and Nusalala dispar in Ecuador. Moreover, ten new records for the Brazilian states are presented: two to Nusalala tessellata and Hemerobius, and one each to Megalomus impudicus, Notiobiella maculata, Sympherobius ariasi, Megalomus, Nusalala and Sympherobius.
Programa para registro de recordatório alimentar de 24 horas: aplicação no Estudo de Riscos Cardiovasculares em Adolescentes
Authors: Barufaldi Laura Augusta , Abreu Gabriela de Azevedo , Veiga Gloria Valeria da , Sichieri Rosely , Kuschnir Maria Cristina Caetano , Cunha Diana Barbosa , Pereira Rosângela Alves , Bloch Katia Vergetti
Published: August 2016

RESUMO: Introdução: O Estudo de Riscos Cardiovasculares em Adolescentes (ERICA) é um estudo multicêntrico nacional cujo objetivo é traçar o perfil de risco cardiovascular, incluindo obesidade, alterações do metabolismo lipídico, glicídico e da pressão arterial de cerca de 75 mil adolescentes brasileiros. Objetivo: Descrever o instrumento desenvolvido para coleta de dados de recordatório alimentar de 24 horas (REC24h) no ERICA e relatar os resultados obtidos no estudo piloto. Métodos: Para o desenvolvimento do programa computacional que norteou a entrevista para aplicação do REC24h utilizou-se a técnica denominada Multiple Pass Method . O REC24h-ERICA utiliza a base de dados composta por 1.626 itens alimentares incluindo as formas de preparo e as unidades de medidas caseiras pré-definidas. Os dados de recordatório alimentar são coletados através de entrevista e digitados diretamente no REC24h-ERICA, evitando assim o uso de papel. Resultados: O estudo piloto incluiu 1.367 adolescentes, dos quais 1.047 (77%) responderam ao REC24h. Os pesquisadores não encontraram dificuldades para uso do programa, a duração média das entrevistas foi de 20 minutos e foram inseridos 50 alimentos novos pelos entrevistadores de campo. Conclusão: O programa desenvolvido mostrou-se adequado para uso em grandes estudos populacionais, mesmo em um país como o Brasil, onde existe grande diversidade de padrões alimentares.
Sobre a Bicha do Bem: queerizar a ética da pesquisa em educação
Authors: Oliveira Thiago Ranniery Moreira de
Published: August 2016

Resumo: Este artigo explora dilemas éticos emergidos de uma pesquisa sobre trajetórias escolares de corpos marcados com experiências de trânsitos de gênero na cidade de Aracaju, Sergipe. Argumenta que a emergência da figura da bicha bem, crucial para o estabelecimento da relação entre pesquisador e sujeitos de pesquisa, abre um movimento para explorar a possibilidade de queerização da ética de pesquisa em educação. Discute como a política de regulamentação ética tem escorregado para uma espécie de normalização. Indica-se também como a figura da bicha do bem sinaliza para a existência de um campo amplo de relações éticas que não pode ser simplesmente circunscrito nem previsto de antemão.
Concepções sobre Violência Intrafamiliar na Área Educacional
Authors: Brino Rachel Faria , Souza Mayra Aparecida de Oliveira
Published: August 2016

Resumo: O objetivo deste estudo foi investigar as concepções sobre violência intrafamiliar entre profissionais e estudantes da área educacional. Utilizou-se a adaptação do questionário Crenças sobre Violência Doméstica. O estudo incluiu 58 participantes. Na análise quantitativa obtiveram-se as médias e porcentagens das respostas adequadas e inadequadas de cada grupo em todos os itens do instrumento, assim como foram verificadas as diferenças estatisticamente significativas nesses itens. Os dados apontaram diferenças estatisticamente significativas em 6 itens e na pontuação total de cada grupo. Os estudantes apresentaram concepções mais adequadas do que os profissionais. Considera-se, por fim, a necessidade de cursos contínuos para atualização profissional.
As diferentes tradições jurídicas:comentários ao projeto de Delmas-Marty sobre internacionalização do direito na América Latina
Authors: Abreu Luiz Eduardo
Published: August 2016

Resumo O objetivo deste artigo é discutir a relação entre o direito internacional e as tradições jurídicas locais de países como o Brasil. Para tanto, o artigo discute a metodologia do projeto de pesquisa da professora Delmas-Marty, do Collège de France, chamado “Les figures de l’internationalisation du droit – Amérique Latine”, no qual vários pesquisadores brasileiros participaram. Propõe-se entender o direito internacional e os direitos nacionais como formas diferentes de linguagem.
Imunidades jurisdicionais do Estado perante a Corte Internacional de Justiça:uma análise a partir do caso Alemanha vs. Itália
Authors: Almeida Paula Wojcikiewicz
Published: August 2016

Resumo Este artigo busca analisar criticamente o caso das imunidades jurisdicionais do Estado perante a Corte Internacional de Justiça, avaliando os principais argumentos tendentes a considerar o caráter não absoluto da imunidade estatal quando estão em jogo sérias violações dos Direitos Humanos e do Direito Internacional Humanitário que possuem o status de normas de jus cogens. Sustenta-se a necessidade de uma leitura progressista da prática estatal em matéria de imunidades estatais, considerando a evolução atual do Direito Internacional e a erosão progressiva da imunidade que caminha pari passu com a limitação da soberania estatal e a emergência do indivíduo enquanto sujeito de Direito Internacional.
Eritrometry in the study of adaptive and reactive status of athletes during training process
Authors: Yatsenko O. ,   KPI"
Published: August 2016

Bring the analysis of the individual characteristics of changes in the index variation of erythrocytes (IVE) and the ratio of different types of cells in the examined eritrona of the basketball players during training. A total of 7 athletes surveyed during weeks 13-16 of the training process. The obtained unstained blood smears calculates the variability of erythrocytes (IVE) by counting the 15 types of red blood cells, classified in the group. On the basis of types for each athlete during these periods of training plotted the percentage of different types of erythrocytes in erythron. In the study of specific features of the definitive components erythron athletes-basketball players found the obvious individual characteristics change as a IVE, and the distribution of the eritron components. In the surveyed athletes club team NTU "KPI" on the basis of selected morphometric study of the eritron funds set individual characteristics manifestations of reactive, adaptive changes of the whole organism during different time periods of the training process.
Reversing the Rubeotic Rampage – Current Approaches in the Management of Neovascular Glaucoma
Authors: Rodrigues Ian A ,   Department of Ophthalmology, St Thomas’ Hospital, London, UK, Lim K Sheng ,   Department of Ophthalmology, St Thomas’ Hospital, London, UK
Published: August 2016

Neovascular glaucoma is a sight-threatening condition, and can rapidly progress from rubeosis with normal intraocular pressure (IOP), to secondary open-angle glaucoma with raised IOP and finally secondary angle-closure glaucoma with uncontrolled IOP. Early detection and aggressive management with panretinal photocoagulation, intravitreal anti-vascular endothelial growth factor (VEGF), topical aqueous suppressants and valved glaucoma drainage surgery can reduce risk of significant visual loss secondary to neovascular glaucoma. This editorial explores some simple measures that can increase surgical success rates and minimise complications.
Perfil epidemiológico do Acinetobacter baumannii resistente a carbapenens num hospital do interior mineiro
Authors: Ciello Giani Del , Araújo Marcelo Costa
Published: August 2016

O objetivo desse estudo foi analisar a prevalência de Acinetobacter baumannii resistente a carbapenens nas amostras biológicas e nos setores do Hospital de Clínicas da Universidade Federal do Triângulo Mineiro. A coleta de dados foi realizada através da análise dos resultados dos exames de cultura presentes nos arquivos do setor de microbiologia do Serviço de Patologia Clínica no período de 2008 a 2014. Dentre as 420 amostras de Acinetobacter baumannii resistentes a carbapenens, as maiores prevalências foram encontradas nos setores de: Pronto Socorro Adulto (26,4%) e Centro de Terapia Intensiva Adulto (22,8%). A prevalência de Acinetobacter baumannii resistente a carbapenem foi maior nas amostras de secreções de ferida (25%), seguidas por amostras do trato respiratório inferior (21,4%). O conhecimento da prevalência do Acinetobacter baumannii resistente a carbapenens é de fundamental importância para que medidas de prevenção e controle das infecções hospitalares sejam implantadas.Descritores: Acinetobacter baumannii; Carbapenêmicos, Resistência a medicamentos.
Hipertireotropinemia transitória e alteração da 17-OH-progesterona em lactente com neuropatia
Authors: Lima Jussara Silva , Cunali Valéria Cardoso Alves , Tubero Luciana De Azevedo , Dos Santos Vandui Da Silva
Published: August 2016

O presente trabalho tem como objetivo relatar o caso de um lactente com neuropatia que apresentou hipertireotropinemia transitória e alteração de 17-OH-Progesterona após estresse cirúrgico complicado com choque séptico e distributivo. As informações foram obtidas por meio de revisão de prontuário, entrevista com os pais, por acompanhamento de evolução, registro dos métodos diagnósticos dos quais o paciente foi submetido durante várias internações e, revisão da literatura. O caso relatado e o levantamento da literatura mostram que são frequentes os valores de TSH alterados e instáveis, bem como alterações de 17-OH-Progesterona, devido a vários fatores, dentre os quais estresse cirúrgico e inflamatório. No caso desse paciente, os fatores neurológicos como os erros inatos do metabolismo mesmo quando não diagnosticados podem intervir na homeostase da criança.Descritores: Hipotireoidismo; Suprarrenal; Erros inatos do metabolismo; Lactente.
El principio de legalidad: una necesaria restricción a la aplicación de la doctrina de los actos propios en la contratación estatal
Authors: Torres-Acosta Luisa Alexandra
Published: August 2016

La jurisprudencia nacional ha aplicado la regla “contra factum proprium quis venire non potest”, en el ámbito de la contratación estatal, con fundamento en el principio de la buena fe. Esta regla dio lugar a la formulación del principio de la confianza legítima para dotar de eficacia jurídica a aquellas situaciones en las cuales un sujeto de buena fe creyó estar bajo el amparo y protección del Estado. No obstante, estas importantes aplicaciones de la buena fe quedan en discusión cuando se advierte comprometida la validez del contrato estatal. Para garantizar la eficacia de las normas imperativas que rigen la configuración del contrato estatal debe primar el principio de legalidad y, en consecuencia, restringirse la aplicación del principio de confianza legítima que en condiciones normales le impediría a la Administración ir en contra de sus propios actos.
Bibliometría para la evaluación de la actividad científica en ciencias de la salud
Authors: Juárez-Rolando Pablo
Published: August 2016

Este trabajo, describe la importancia de la investigación bibliométrica para la evaluación de la actividad científica en Ciencias de la Salud, considerando en la misma la producción científica Latinoamericana. Un nuevo conocimiento,producto de la investigación científica, adquiere valor cuando se publica y posteriormente es aplicado en el campo específico del estudio, contribuyendo al desarrollo de la sociedad; en este sentido, los resultados de estudios bibliométricos han adquirido una importancia creciente en la elaboración de la políticas de investigación científica y su gestión en el área de la salud.
Transmisión de infecciones nosocomiales por el personal de salud
Authors: Llanos-Cuentas Alejandro
Published: August 2016

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Factores asociados a hiponatremia adquirida en la comunidad
Authors: Pérez Sierra Henry , Ramírez Zegarra Rafael , Cieza Zevallos Javier
Published: August 2016

El desarrollo de la hiponatremia en la comunidad es un aspecto poco estudiado, y su frecuencia y los factores que la condicionan son poco conocidos. Objetivos: Estudiar los factores clínicos y de laboratorio asociados a la hiponatremia de pacientes incidentes en el servicio de emergencia de un hospital general. Material y métodos: Estudio de casos y controles. Los casos fueron pacientes con Na+ sérico<135 mEq/l al momento de ser admitidos en el Departamento de emergencia del Hospital Cayetano Heredia y los controles pacientes hospitalizados al mismo tiempo que el caso, cuyo Na+ sérico estuvo entre 135 y 145 mEq/l. Fueron excluidos pacientes con creatinina sérica >5 mg/dl. Se contrastaron las variables edad, sexo, sistemas comprometidos, gravedad del paciente y valor de los electrolitos; gases arteriales; urea y creatinina. El tamaño de muestra fue de 20 casos y 40 controles (confianza 95%, potencia 80% y OR 4). Resultados: Los casos y controles difirieron estadísticamente en los valores de cloro sérico y pH arterial. Solo hubo asociación estadísticamente significativa entre la existencia de mayor proporción de alcalosis metabólica, valores más bajos de la creatinina y razón urea/creatinina >50 de los casos en relación a los controles. Enel análisis de regresión logística binaria la alcalosis metabólica fue la única variable estadísticamente significativa. Conclusiones: La hiponatremia adquirida en la comunidad estuvo relacionada principalmente a la presencia de alcalosis metabólica y secundariamente a la creatinina baja, probablemente reflejo de una contracción del volumen circulante efectivo en personas desnutridas.
Histoplasmosis diseminada con síndrome hemofagocítico asociado con infección por HTLV-1. Reporte de caso
Authors: Ventosilla Ronald , Del Carpio Daniel
Published: August 2016

Síndrome hemofagocítico (SH) es un cuadro sistémico severo usualmente fatal, reportado como causa secundaria en adultos. Histoplasmosis ha sido descrita como una de las causas, siempre en pacientes con inmunosupresión. Se presenta el caso de un paciente varón natural de Huánuco con historia de tos y expectoración de dos meses e infiltrado pulmonar intersticial y parenquimal basal derecho con adenopatía mediastinal. Ingresó con fiebre, pancitopenia, alteración de pruebas hepáticas y pruebas de coagulación que cumplía criterios de SH. En el aspirado de médula ósea se observaron inclusiones intracitoplasmáticas en los macrófagos compatibles con Histoplasma capsulatum. La serología para HTLV-1 fue positiva por lo que se analiza el rol de este virus como agente inmunosupresor que condiciona SH secundario a histoplasmosis diseminada.
Actualidad y perspectivas del HLA en el trasplante renal
Authors: Chang Dávila Domingo
Published: August 2016

La introducción de la compatibilidad en los antígenos leucocitarios humanos (HLA) en la selección de los injertos para trasplante renal ha mejorado la sobrevida y el pronóstico del órgano trasplantado, a corto y largo plazo. Sin embargo, recientes observaciones sugieren que la importancia relativa de los HLA ha disminuido en décadas recientes. Posibles explicaciones para este fenómeno incluyen la reciente utilización de terapias inmunosupresoras más potentes, una mayor importancia relativa de antígenos no HLA y factores no inmunológicos.
KUALITAS TERASI UDANG DENGAN SUPLEMENTASI PEDIOCOCCUS HALOPHILUS (FNCC-0033
Authors: Soetikno Nooryantini , Fitrial Yuspihana , Khairina Rita
Published: August 2016

Terasi is condiment of formed solid, its flavour typically result of shrimp fermentation or mix of them with salt or other additional substance. The aim of this research is to know  influence of the supplementation P. halophilus (FNCC-0033) isolate, to time of fermentation and quality of terasi shrimp. This research by complecated Randomized Design with 3 repetition’s. The treatment given are supplementation P. halophilus 2,5 x 104 CFU/g (A), P. halophilus 5,0  x 104 CFU/g (B) and processing terasi without addition P. halophilus (FNCC-0033) as control (treatmen O). Measure of chemical parameter total N, water content, TVB and pH, the microbiologis parameter are total microbe and total LAB, and parameter organoleptic are colour, odour and texture. The research conducting days fermentation by each every 7 days during 28 days fermentation. Based on TVB value  total microbe and total lactid asid bacteria show that had been formed at 21th  days fermentation.The result of analysis of varians showed differenct betwen observed day fermentation. The conclusion of this research showed processing terasi by supplementation of  P. halophilus have similarity wich spontanious fermentations. The total microbe are supplementation to terasi able resulted of more fermentation time is quicker than spontanious fermentation.
A Supervised Classification Method for Levee Slide Detection Using Complex Synthetic Aperture Radar Imagery
Authors: Marapareddy Ramakalavathi , Aanstoos James V. , Younan Nicolas H.
Published: August 2016

The dynamics of surface and sub-surface water events can lead to slope instability resulting in anomalies such as slough slides on earthen levees. Early detection of these anomalies by a remote sensing approach could save time versus direct assessment. We have implemented a supervised Mahalanobis distance classification algorithm for the detection of slough slides on levees using complex polarimetric Synthetic Aperture Radar (polSAR) data. The classifier output was followed by a spatial majority filter post-processing step which improved the accuracy. The effectiveness of the algorithm is demonstrated using fully quad-polarimetric L-band Synthetic Aperture Radar (SAR) imagery from the NASA Jet Propulsion Laboratory’s (JPL’s) Uninhabited Aerial Vehicle Synthetic Aperture Radar (UAVSAR). The study area is a section of the lower Mississippi River valley in the southern USA. Slide detection accuracy of up to 98 percent was achieved, although the number of available slides examples was small.
Biological Activities of the Essential Oil from Erigeron floribundus
Authors: Petrelli Riccardo , Orsomando Giuseppe , Sorci Leonardo , Maggi Filippo , Ranjbarian Farahnaz , Biapa Nya Prosper C. , Petrelli Dezemona , Vitali Luca A. , Lupidi Giulio , Quassinti Luana , Bramucci Massimo , Hofer Anders , Cappel Loredana
Published: August 2016

Erigeron floribundus (Asteraceae) is an herbaceous plant widely used in the Cameroonian traditional medicine to treat various diseases of microbial and non-microbial origin. In the present study we evaluated the in vitro biological activities displayed by the essential oil obtained from the aerial parts of E. floribundus, namely the antioxidant, antimicrobial and antiproliferative activities. Moreover, we investigated the inhibitory effects of E. floribundus essential oil on nicotinate mononucleotide adenylyltransferase (NadD), a promising new target for developing novel antibiotics, and Trypanosoma brucei, the protozoan parasite responsible for Human African trypanosomiasis. The essential oil composition was dominated by spathulenol (12.2%), caryophyllene oxide (12.4%) and limonene (8.8%). The E. floribundus oil showed a good activity against Staphylococcus aureus (IZD of 14 mm, MIC of 512 µg/mL). Interestingly, it inhibited the NadD enzyme from S. aureus (IC50 of 98 µg/mL), with no effects on mammalian orthologue enzymes. In addition, T. brucei proliferation was inhibited with IC50 values of 33.5 µg/mL with the essential oil and 5.6 µg/mL with the active component limonene. The essential oil exhibited strong cytotoxicity on HCT 116 colon carcinoma cells with an IC50 value of 14.89 µg/mL, and remarkable ferric reducing antioxidant power (TEAC= 411.9 μmol TE/g).
Transient Pressure Analysis of Horizontal Well with Slanted Hydraulic Fractures and Drainage Volume Characterization Using Fast Marching Method
Authors: Han Jichao , Yang Changdong , Huang Jixiang
Published: August 2016

Horizontal well drilling and multistage hydraulic fracturing are essential to economic recovery of unconventional tight/shale reservoirs. Multiple transverse fractures are ideally supposed to be perpendicular to the minimum stress direction, but slanted fractures might be seen in practice, which might bring a better connection between wellbore and fractures. However, for the same fracture half-length, the stimulated reservoir area might be less. Thus, the well performance of slanted faractures is full of uncertainty. Little research work is currently conducted on the horizontally slanted fracture scenario.

Our transient pressure analysis of horizontal well performance with slanted hydraulic fractures utilizes the concept of rate-normalized pressure and transient productivity index. The novel Fast Marching Method (FMM) is adopted to characterize the drainage volume evolution for multi-stage horizontal wells and validate the proposed methodology. Sensitivity studies contrast transient pressure behavior and productivity index for slanted fracture angles from 0 to 90 degrees, e.g. from longitudinal to transverse fracture angles. Additionally, transient pressure behavior and long term reservoir performance of horizontal well for different scenarios are investigated, such as reservoir anisotropy and different proppant allocation strategies under the constraints of given horizontal well spacing and total proppant mass.

Contrast to what we are usually expecting, results show that for the same fracture spacing, and the same total proppant mass, the well with slanted fractures will have a higher productivity index than that for strictly transverse fractures. Different from productivity index, the long term reservoir performance, however, turns out to play a different game, given specific horizontal well spacing and the same total proppant mass. Reservoir performance for horizontal well with slanted hydraulic fractures can be significantly improved by optimally allocating the proppant and designing hydraulic fracture placement strategies through this research.
Years of Tight Oil Fracturing: What Have We Learned?
Authors: Wang Yucai , Wang Zhonghe P. , Zhang Yingan , Xu Jianguo , Duan Yongwei
Published: August 2016

Production rapid decline is the major problem for the tight sandstone reservoirs in Jilin oilfield. For the particular reservoir investigated in this study, production is not only subjected to the reservoir properties, but also the well completion designs especially fracturing. A comprehensive study has been conducted for multi-stage fractured horizontal wells. New fracturing improvement strategies are presented in this paper for future operations in the studied field and also those who may have similar tight sandstone reservoirs to share.

Through the integrated studies of the petrophysical characteristics, geomechanical properties and fracturing data from the fractured wells of the tight oil reservoirs in Jilin Field, numerous fracturing modeling scenarios were compared with actual fracturing monitoring data. A fully three dimension finite element simulation, associated with the analytical result from earlier production data, and the theory of interaction between fracture clusters, were built in this study. We conducted the inversing design parameters from the multi-stage hydraulic fracture with some monitoring data to improve the understanding of the reservoir properties. Additionally, a calibrated geomechanical stress model for a completed well in this field was built. At the end, the production model was presented. Data was provided to facilitate later comparison with the actual multi-stage hydraulic fracture production and valuable lessons have learned through those iteration studies.

With thoroughly trained and well calibrated model, a new fracturing strategy has been developed for the studied tight oil field. The best NPV can be achieved with the optimal fracture conductivity, fracture geometry and well performance. But first of all, the most valuable lesson we learned is that, the Effective Propped Volume (EPV) is the dominating factor for the fractured well performance, instead of the so-called Stimulated Reservoir Volume (SRV). SRV is a misinterpreted concept yet un-calculable. By adopting a numerical simulator and a proficient technology, we developed the most suitable design (perforation, fracture spacing etc.) and the fluid system (slick water, linear gel etc.) for this reservoir so that the optimal fracture geometry and fracture conductivity can be achieved. Besides that, the fracture geometry and proppant distribution were simulated. The simulated oil production data from the finite element fracture and production software is highly matched with the recorded oil production data.

An adaptability evaluation was conducted along with this study. To ensure the relevance and the authenticity of design, we analyzed the effective factors of treating material from both the laboratory and the field data in this field. A novel fracturing fluid system was applied. The fluids are more effective and leave less damage to the formation.
Comprehensive Modeling of Downhole Temperature in a Horizontal Well with Multiple Fractures
Authors: Yoshida Nozomu , Hill A. D.
Published: August 2016

Downhole temperature data obtained by either temperature logging or fiber-optic cables have been used to evaluate stimulation treatments and post-stimulation performance of horizontal wells with multiple fractures. Field cases qualitatively show capabilities of detecting creation of transverse fractures, poor zonal isolation, and inflow locations, although downhole temperature behavior in those wells are not fully understood from the theoretical modeling perspective.

In this study, we present comprehensive numerical flow and thermal models for a horizontal well with multiple fractures. The well experiences single-phase water flow during injection and shut-in, and gas-water two-phase flow during production. These models are formulated for reservoir and wellbore domains with consideration of their coupling. The reservoir models are formulated in three-dimensional space on the basis of mass conservation of each component and thermal energy conservation with Darcy's law in transient conditions. The wellbore models are also transient, and formulated for one-dimensional space on the basis of mass conservation of each component, conservation of combined-phase momentum, and total energy conservation. The wellbore and sandface temperature profiles are obtained as solutions of these models. These models enable us to simulate field operations in multi-stage fracturing treatment; injection and shut-in occur alternately for each stage from toe to heel with zonal isolation. Following the stimulation treatments, these models are used to simulate temperature behavior during production in gas-water two-phase flow.

We show an example of a single fracture in which the developed model simulates temperature behavior during injection, shut-in and production to show capabilities of the developed model. This study shows injected fluid makes the fluid temperature in the fracture lower than the geothermal temperature even after one month of shut-in. This affects the temperature interpretation during production because the initial temperature is different from the geothermal temperature assumed as initial temperature by most studies published before. A synthetic case with five fractures demonstrates capabilities of detection of created fracture locations from the shut-in temperature profile. In addition, we apply the model to a field case. The case studies justify qualitative interpretations in situations occurring in fields such as warm-up behavior with multiple clusters during shut-in period.

This paper provides insights from the theoretical modeling perspective for the downhole temperature interpretation qualitatively performed at current time. It also discusses validity and precautions of the assumptions made in previous studies.
Impacts on SRV Region in Low-Permeability Formations Due Stressse Around a Hydraulic Fracture
Authors: Wang Yarlong , Karaoulanis Fotios
Published: August 2016

Stresses induced near a hydraulic fracture are calculated in an elastoplastic Mohr-Coulomb type formation. While an effective compressive stress increase may reduce the permeability in the formation, the induced shear stresses and dilatant zone developed can increase the stimulated reservoir volume (SRV) and the size of an enhanced permeability zone. Therefore, the induced shear stresses and dilatant zone are used in this article in order to quantify the size of the SRV. It is emphasized that when the SRV can be characterized by elastic strains generated during a fracturing process, this reversible SRV may not be maintained during production. It is those irreversible SRV (ISRV) or dilatant volumetric strains that are the key for producing low-permeability reservoir economically. It is suggested therefore that a production enhancement in these formations is dominated by the possible ISRV which are quantified by the cohesion, the orientation of the natural fracture network and in-situ stress ratios.
Fracturing Carbonate Reservoirs: Acidising Fracturing or Fracturing with Proppants?
Authors: Jeon Jiwon , Bashir Muhammad Omer , Liu Junrong , Wu Xingru
Published: August 2016

Carbonate reservoir with low permeability is developed using fracturing technology to effectively stimulate the reservoir for a higher productivity. However, as the carbonate reservoir features extreme heterogeneity, not every fracture is created equally as is obtainable through acidizing fracturing or using proppant. The objective of this study is to help make the decision among acid fracturing or proppant fracturing, to achieve an economically and operationally feasible treatment through extensive research of field cases on critical factors and numerical simulation.

An ideal fracturing method of a carbonate reservoir should yield a high conductive fracture with a potential for long production duration under depletion scenario within an economic limit. We first review real field cases to identify critical parameters affecting fracture geometry and productivity; then we validate and quantify their individual effectiveness using 3D synthetic models with numerical simulation. In the simulation work, both treatments are evaluated by simulating the production of the reservoir for 1,500 days post treatment. Results are compared for different reservoir parameter variations including porosity, permeability, temperature, depth and young's modulus. Simulation of the field is continued for 1,500 days after the treatment to see the effect of the production enhancement for both types of treatment. This is also done to include long term loss of fracture conductivity and its effect on the overall production. Fracture geometry from each case is also analyzed and compared to the base case scenario.

Even though hydraulic fracturing and acidizing technologies have been the dominant stimulation methods in unconventional resources and many variants have been developed, there is still no well-defined guideline which can help an operator to select the stimulation techniques suitable for their particular fields. This paper focuses on factors influencing decision making on the stimulation of carbonate reservoirs based on reservoir characterization. The advantages and limitations of proppant fracturing and acid fracturing are compared based on field applications, which can enable an operator to make quick and informed decision on which stimulation should be used. Numerical effort confirmed and quantified our observations. Comparisons have been drawn on different types of proppant and acid treatments and their effectiveness on the target reservoir. The study eventually comes up with identifying main factors of reservoir for treatment selection and recommendations are presented from these findings that which type of reservoir is best suited for which type of treatment.

The novelty of the study is summary of previous field cases with a clear guideline on making decision in carbonate reservoir stimulation. As a further extension to this study, PVT data can also be included to see the extent of reservoir fluid change effect on the outcome of the treatment.
Laboratory Testing and Numeric Simulation on Laws of Proppant Transport in Complex Fracture Systems
Authors: Li Nianyin , Li Jun , Zhao Liqiang , Luo Zhifeng , Liu Pingli , Guo Yujie
Published: August 2016

Stimulated reservoir volume fracturing, in unconventional gas and tight oil development, is a key technology. Injecting low viscosity sand-laden fluid of high flow rate, it can form complex fracture networks. Therefore, placement of proppant deep into the complex fracture networks brings a conductive path for production enhancement and reduces flowing resistance when fluid flowing form rock matrix to wellbore.

At current, it is still unclear that sand features of low viscosity sand-laden fluid of high flow rate, and especially for proppant transport in subsidiary fractures are also not clearly understand. In this study, we fully think about the practical condition of engineering. Thus, in terms of similarity criterion of geometry and Reynolds number, we build a large scale of proppant placement in visualization complex fracture networks device which can changes angles of fractures, width of fractures and numbers of fractures. Due to the single factors experiment, this paper will discuss a series tests to evaluate proppants transport in complex fracture networks. Different slick water treatment tests are simulated by pumping sand slurry through the visualization complex fracture networks device while varying parameters of perforation, angles of fractures, proppant size, pump rate and proppant concentration. From the experiment, treatment tests which are used in variable factors can obtain different laws about traction carpet feature, traction carpet areas, balance hight and balance time in complex fracture networks. This paper also describes a 3-D physical model. This model is designed by SolidWorks software and using grid software to make complex fracture grids. Afterwards, using fluent software to simulate proppant concentration distribution field in the model of complex fracture networks. In addition, comparing the results between physical model and numerical model, the results can reveal, during the process of SRV, the law of proppant placement in complex fracture networks and serve as guidelines for engineering design.
A New Acid Fracturing Fluid System for High Temperature Deep Well Carbonate Reservoir
Authors: Gao Ying , Lian Shengjiang , Shi Yang , Yang Xianyou , Zhou Fujian , Xiong Chunming , Li Futao , Han Xiuling , Zhang Na
Published: August 2016

When a high temperature deep well carbonate reservoir is stimulated with conventional acid fluid, some unfavorable behaviors often occur, such as high acid-rock reaction rate, short effective reaction distance of live acid, failure of acid etching in the acid fracture front, and serious corrosion to downhole string. This paper presents a new acid fracturing fluid system. This system consists of the acid-generator SGA-E, the optimized polymeric thickener CHJ-1 and the cross-linking agent SJL-1. With the performance of water-based fracturing fluid, this system can be used as prepad during acid fracturing. Moreover, this system has weak or no acidity at low temperature and slow release of H+at high temperature (120-150°C) in fractures, Its ultimate effective acid concentration is about 8% which is capable of effective acid etching. During pumping, this system shows less corrosion to the string, so few corrosion inhibitor is required. This new acid fracturing fluid system can achieve effective acid etching of a whole fracture, so as to increase the stimulated reservoir volume.