bluuebunny/crossref_metadata_2025 huggingface dataset:
Amplifying the voices of underrepresented speech-language pathologists through research: A transformative scoping review
Authors: Gréaux Mélanie , Chadd Katie , Gheewala Fatima , Pang Voon , Katsos Napoleon , Gibson Jenny Louise
Published: June 2023

Purpose: To investigate the characteristics of studies that included underrepresented speech-language pathologists (SLPs) as research participants, to better understand the knowledge that was generated, the research processes that were used, and the extent to which they could enable empowerment of participants.Method: A scoping review was conducted according to the principles of the transformative research paradigm, which promotes the involvement of marginalized groups in ways that amplify their voices, value their knowledge, and address power inequities. Consultation and co-production with minority SLPs were facilitated. The search strategy was run in six databases, and the transformative checklist was used to analyse the studies. Results: 20 studies were included. Bilingual and male SLPs were among the most commonly included underrepresented SLPs. Most studies were conducted in the USA (n=16), and used quantitative survey methods to investigate SLP service delivery with disaggregation of data by SLPs with different attributes. Findings of the included studies provided valuable insights into the unique experiences and practices of underrepresented SLPs, and yielded practical solutions to foster inclusion and diversity in the profession. Most studies demonstrated a transformative potential, but the authors’ plans to achieve change were often unclear, and the active engagement of underrepresented SLP participants in the research cycle was demonstrated in only five studies.Conclusion: This review calls for a shift in how and why research is conducted when including underrepresented SLP participants. Through the lens of the transformative research paradigm, we can rethink the broader aim of research and the role of researchers and participants. Using research as a platform to give visibility, voice and agency to the minority members of our community can shape the evidence-base and inform tomorrow’s SLP practices, hence becoming an empowering mechanism to stimulate change and equity in the profession.
Proportion and Characteristics of Amino Acids Flavoring Powder for Biang Fish (Ilisha elongata)
Authors: Hidayati Aulia , Sumarto Sumarto , Suparmi Suparmi
Published: June 2023

This study aims to determine the proportions and characteristics of amino acids for the flavoring powder of the fish with different concentrations of the fish meal. The method used in this research is an experiment of making fish seasoning powder with the use of ingredients consisting of fish meal, onion, garlic, iodized salt and white pepper with a non-factorial completely randomized design consisting of 4 levels of treatment, namely P0 (0 grams of powder biang fish), P1 (60 grams of powder biang fish), P2 (70 grams of powder biang fish), P3 (80 grams of powder biang fish). The results showed that the proportion of fish meal was 23% and the analysis of types and levels of amino acids produced 9 types of essential amino acids with the highest number found in isoleucine 0.882% and 8 types of non-essential amino acids with the highest amount found in glutamic acid, namely 1,337 % .
Causes of Low Performance in English at College Level: Teachers’ Perspectives
Authors: Chand Gambhir Bahadur
Published: June 2023

This study, “Causes of low performance in English at college level: Teachers’ Perspectives,” aimed to explore the teachers’ perspectives on the causes of low performance in English and suggestions forth improvement for the college level students. The data were collected from twenty teachers teaching at the college level in the Far Western part of Nepal using a general qualitative research design. The study used a questionnaire containing open ended questions to collect their perspectives and shared the question using Google form. Collected data were analyzed, forming two themes based on the questions: causes of low performance and suggestions for improvement. The collected data showed that classroom interaction, teaching methods, learners, curriculum, and evaluation system are the main causes of low performance. They have suggested increasing interaction in the classroom, changing teaching method sat the college level, revising the existing courses, and changing the examination system in the university to improve the level of performance of the students, especially at the college level.
General extralinguistic factors reinforcing specific ideas about the Cheboksary regiolect of the Russian language
Authors: Fomin Eduard Valentinovich
Published: June 2023

The study is devoted to the study of the conditions for the formation and functioning of the Cheboksary regiolect of the Russian language, which is distinguished by a number of stable linguistic parameters. The peculiar sound of the speech of the Cheboksary people has developed under the significant substrate influence of the Chuvash language, among the speakers of which there are currently active processes of a linguistic shift in favor of Russian. The work is written in the aspect of sociolinguistics and is based on the author’s long-term observations of the self-esteem of Cheboksary residents and their assessment by visitors. The purpose of the research is to expand the understanding of extralinguistic factors that do not directly affect the specifics of the speech of Cheboksary people, but at the same time enhance the impression of it from outside observers. The article deals with non-linguistic specific features inherent in the capital of the Chuvash Republic, including geographical, climatic, anthropological, technological and other components. Their presence greatly enhances the perception of the sound of the Russian speech of the inhabitants of Cheboksary and its agglomeration as a unique phenomenon of modern Russian culture. In turn, the specific conditions that support the Cheboksary regiolect are the result of a long historical and social process, including the mass migration of the population in the past, the mixing of different ethnic groups among themselves and the formation of modern peoples in their visually fixed physical features, anthropological impact on the ecumene, etc. in relation to the territory of Chuvashia and nearby regions.
Chuvash mystical stories: content component
Authors: Fedotova Elena Vladimirovna
Published: June 2023

The work is devoted to the analysis of texts of Chuvash epics recorded from the end of the XIX to the beginning of the XXI centuries. in the Chuvash villages of the Volga-Ural region. The purpose of the study is to identify the features of the content of the texts of Chuvash bylichek, to introduce them into scientific circulation. The study presents the classification of bulls compiled by the author. The work is based on archival and own field materials. The texts are analyzed in a descriptive aspect. At the same time, the author turns to ethnographic and linguistic approaches in the work. A distinctive feature of the Chuvash bylichka is its content: a description of the landscape, furnishings, traditional costume, jewelry, local cultural features. In addition, bylichkas are characterized by enumeration of endemic toponyms, details, the use of certain sets of plots, the mention of household items, tools, harness items, and the performance of various kinds of deeds. The most amazing are the narratives about the transformations of people with supernatural abilities into various household items (cloth, chair, pillow) or into animals (cat, dog, calf, lamb) and back into a person, the transformation of the mortgaged dead into horses, harness items. The ending of the epics often contains the syncretism of two religions: pre-Christian and Christian.
Regional development study how to develop a small city affected by siphoning: A case of a Chinese city
Authors: Song Gui , Cai Jing , Fu Yingjie
Published: June 2023

Small cities located on the periphery of large cities have long faced challenges such as difficulties in economic development and population loss, especially in China. The concentration of a few super-large cities in China has hindered the growth of per capita income in most small cities and led to a widening income gap between cities. In addition, studies have shown that central cities can have a polarizing impact on surrounding areas thereby hindering economic growth. To address these issues, this paper examines Baoding, a small city close to the capital, Beijing. Through literature and policy research, we analyse how Baoding can take advantage of the Beijing-Tianjin-Hebei integration policy and pursue its urban development in the presence of neighbouring large cities. By providing theoretical suggestions the research contributes to Baodin’s urban development through five potential industries: healthcare, automotive, electronics, digital, and tourism. Furthermore, we emphasize the practical contributions such as: the importance of higher education as a key driver of sustainable development for the city. Based on our analysis, we suggest that Baoding’s strategic development direction should be aligned with Beijing’s needs while recognizing that such alignment is merely a means to an end. The goal of urban development should always be to improve the living standards and well-being of citizens.
A perspective of technology among healthcare provider after the pandemic
Authors: Dini Yunita Arga , Bukuku Debora
Published: June 2023

The rapid spread of the COVID-19 virus has brought about a serious public health emergency on a global scale. There is a considerable need for essential digitally-enabled medical equipment and accessories, as well as for quarantine facilities, surveillance systems, and other related digital technologies. In the fields of healthcare, manufacturing, and education, technologies that facilitate working remotely from safe areas are absolutely necessary. It is possible that digital technology and the tools of Industry 4.0 will be able to satisfy these specific requirements both during and after the COVID-19 crisis. The experts in the healthcare industry can use this perspective to better cope with the difficult times that follow a pandemic.

Keywords: Virus infection; COVID-19; Industry development; digital technology; medical care
A viewpoint on evaluating ECG findings to assess heart issues: A clinical nursing review
Authors: Saputra Dikki , Suhartini Suhartini , Sujianto Untung , Ismail Rifky
Published: June 2023

The 12-lead EKG is a useful first-line diagnostic tool for detecting cardiovascular diseases, including arrhythmias, conduction abnormalities, and myocardial ischemia or infarction. This scoping review aims to discuss the ECG perspective for detecting heart problems. This study was conducted by following the narrative review and development framework. The literature search used ScienceDirect, Scopus, ProQuest, ClinicalKey, and SpringerLink data. The keywords used were "criteria" or "guidelines" and "ECG" or "ECG" or "electrocardiography" or "electrocardiogram" and "detection" and "heart problem" or "heart disease" or "heart problem" or "heart problem." The method uses a narrative review through eight articles spanning 2017–2022. The lighting method uses the PICO analysis framework. The results found four components, namely: 1) automatic diagnosis; 2) 3-D ECG with artificial intelligence (AI) classification; 3) use of the LSTM deep-learning model; and 4) leads using Tpeak-End (Tp-e). In patients with heart problems, the initial examination is an EKG. Thus, the ECG, with the addition of the automatic diagnosis feature, EKG-3D, and the use of a 12-lead ECG with a deep-learning LSTM model, also followed by high sensitivity and specificity, can be used as a tool to perform examinations on patients who require serial ECG examinations.

 Keywords: Electrocardiogram; nursing care; nursing review; clinical symptoms; nursing assessment
Equate access to primary health care in rural Kalimantan: what essential health services should be available locally?
Authors: Rahman Ferry Fadzlul , Haris Fahni , Irawati Kellyana
Published: June 2023

Indigenous and remote ethnic populations experience poorer health status than metropolitan populations due to unequal access to essential healthcare services (Primary healthcare). This study aims to assess which essential health services are best provided by health workers and describe the service needs problem from the patient's perspective. The Delphi method consists of informants represented by rural and remote health centers. Using open-ended questions, they represent the population for each health center service. Each question must identify a problem based on the core of essential health services. The results of the study show that the criteria that must be met include the importance of equality in health services; consideration of social determinants of health; flexibility, effective resource budgeting, adjusting the type of health services according to patient needs, and providing assistance as close to home as possible. The conclusions of this study can help policymakers and service planners to determine what types of service needs should be provided by health workers in remote areas, to allocate resources and provide services more equitably, and to inform patients about healthcare services that they expect to be able to access pretty within the community.
Keywords: Health care system; community nursing; nursing care; delphi study; health population
Collaboration between interprofessional education (IPE) and interprofessional collaborative practice (IPCP) in health education: A narrative review
Authors: Gautama Made Satya Nugraha , Kharismawati Fiyanisa Aziza , Astuti Leny Fadayu , Maulidyati Maulidyati , Hidayatulloh Aziz
Published: June 2023

Interprofessional Education (IPE) and Interprofessional Collaborative Practice (IPCP) have become essential educational approaches to improve the collaboration system and quality of health services. This study aims to provide an overview of the IPE/IPCP implementation strategy focusing on achieving core competencies and their outcomes.  The narrative literature review study preferred the PRISMA model approach. The articles were analyzed from three electronic databases, ScienceDirect, Scopus, and PubMed.  The search keywords used “Healthcare professional” AND “Interprofessional practice” OR “interprofessional education” AND “Nursing education” AND “Improved competencies” with the study criteria involved students or health professionals, last ten years, English version, and used experimental or observational, mixed methods design. A total of 14 articles met the criteria and were summarised. As a result, the IPE/IPCP implementation strategies with simulation, curriculum, and training focused on the main competencies produced essential outcomes, including increasing knowledge, skills, positive attitudes, and perceptions of students and health professionals and improving the quality of patient care. IPE/IPCP strategies such as an integrated curriculum, simulation, and training program were recommended for implementation in the institution or clinical setting. Sustainable IPE/IPCP strategies and outcomes are essential in promoting collaborative practice and quality healthcare.
Keywords: Healthcare professionals; collaboration; nursing curriculum; higher education; quality of care
Psychological distress scale among caregivers in delivering care of patients with post-stroke rehabilitation: A validity and reliability testing study
Authors: Paramartadewi Paramartadewi , Bashori Khoiruddin , Hidayah Nurul
Published: June 2023

A stroke is a condition of blockage in the cardiovascular system. Patients who have passed the stroke phase are post-stroke rehabilitation patients who receive outpatient care. Caregivers help patients carry out daily activities during the rehabilitation process. Workload as a caregiver is a cause of psychological distress. The physical and emotional domains affect caregivers experiencing psychological distress, so caregivers become less psychologically healthy and less optimal in helping post-stroke rehabilitation patients. Researchers adapted the scale, namely Kessler's 10 Psychological Distress Scale (K-10), to see the level of psychological distress in caregivers of post-stroke rehabilitation patients—adaptation using Indonesian with the research participation of 43 people from Yogyakarta. Data were taken using accidental sampling on caregivers of post-stroke rehabilitation patients in Yogyakarta. Reliability testing was conducted using Cronbach's alpha, with the final result of p = 0.884, and construct validity testing using confirmatory factor analysis (CFA) with a measurement model. The results of this scale indicate that Cronbach's alpha is 0.884, and the CFA model is considered appropriate. Based on this, the results of this study suggest that the Psychological Distress Scale is reliable and valid so that it can be used for caregivers of post-stroke rehabilitation patients in Indonesia. In addition, this research scale can be used in health psychology, especially psychological distress.
 Keywords: Stroke; caregiver; nursing care; community care; rehabilitation care
The impact of servant leadership in nursing practice at the hospital: A literature review
Authors: Purwanti Rosalia Yuli , Sriatmi Ayun , Dwiantoro Lucky
Published: June 2023

Leadership style in nursing has influenced nurses and patients at hospitals. One of the styles suitable to put into practice is servant leadership, as there found valuable similarities in characteristics, such as being altruistic, serving, and healing. Servant leadership in nursing is closely related to the ability to influence nurse teams and hospital patients. This study aims to identify servant leadership's effects on nurses as a team and patients at hospitals. The research method used is the literature review. Database Sciencedirect, Proquest, Scopus, Clinicalkey, and SpringerLink are explored to search the desired articles by selecting keywords "Servant Leadership" AND "Patient" AND "Nurse." Papers selected as the data sources meet the following inclusion criteria, i.e., full-text articles published between 2012-2022 and discussing servant leadership in nursing. After studying four pieces, it is found that servant leadership acts on both nurses and patients. The effects of servant leadership on nurses are in innovative behavior, job performance, and nurse satisfaction. In contrast, its impact on the patients is in their satisfaction after using the health care services.
Keywords: Leadership; nursing management; quality of care; nursing care; clinical nursing practice
Pterosphenus muruntau – valid species of sea snakes (Squamata: Palaeophiidae) from the middle Eocene of Uzbekistan
Authors: Averianov A.O.
Published: June 2023

A palaeophiid sea snake Pterosphenus muruntau Averianov, 1997 was based on two trunk vertebrae and several vertebral fragments from the middle Eocene (Bartonian) coastal marine deposits of Dzheroi 2 locality in the Central Kyzylkum Desert, Uzbekistan. The species was considered a nomen dubium by Rage and coauthors in 2003 based on alleged poor preservation of the type specimens. However, the preservation of the holotype of P. muruntau is sufficient to discern a slightly laterally compressed vertebra and a low pterapophysis, the characters that distinguish this species from the other species of Pterosphenus. These characters are also clear in a new and better preserved vertebra of P. muruntau from the type locality. Pterosphenus muruntau should be considered a valid species of the genus Pterosphenus.
Odpowiedzialność karna w kosmetologii
Authors: Gąsowski Mateusz , Guzik-Makaruk Ewa Monika , Kuligowska-Tyszka Adriana
Published: June 2023

Współcześnie zabiegi wykonywane w gabinetach kosmetycznych cieszą się coraz większym zainteresowaniem. Jednak funkcjonowanie tego rodzaju gabinetów i określenie katalogu zabiegów, które mogą być wykonywane w tych gabinetach wciąż pozostaje nieuregulowane prawnie. W przypadku nieudanego zabiegu bądź też wykonania zabiegu przez osobę do tego nieuprawnioną lub przy użyciu produktu, którego zastosowanie możliwe jest wyłącznie przez lekarza można rozważać odpowiedzialność karną za te czyny. Niniejsze opracowanie ma na celu wskazanie podstaw prawnych wykonywania zawodu kosmetologa, w tym określenie uprawnień kosmetologów. Ponadto, podjęto próbę określenia zasad funkcjonowania gabinetów kosmetycznych, a także podstaw karnoprawnej odpowiedzialności kosmetologów za przestępstwa popełniane przy wykonywaniu zabiegów.
Релігійна активність і релігійний світогляд українців в умовах запровадження нової радянської обрядовості: роки хрущовської «відлиги» та розгортання брежнєвського «застою»
Authors: Кіндрачук Надія
Published: June 2023

Метою статті є вивчення прагнення українців зберегти свою власну національно-духовну ідентичність у процесі впровадження КПРС – КПУ нової радянської обрядовості в роки хрущовської «відлиги» та розгортання брежнєвського «застою». Методологія дослідження. Під час здійснення дослідження застосовано конкретні наукові методи, зокрема аналітико-логічний, історико-системний, пояснення, пошуку, синтезу, співставлення та комплексного добору. У роботі також використано метод аналізу – для з’ясування рівня зростання національної свідомості українців. Наукова новизна. У статті аргументовано доведено, що незважаючи на антирелігійну політику КПРС – КПУ, насадження «нової радянської обрядовості», споконвічні церковно-релігійні традиції та звичаї українського народу і надалі залишалися складовою повсякденної культури українців. Висновки. Так, «нові обряди» стали черговою «цеглиною», закладеною комуністами у твердиню денаціоналізації та радянізації українського етносу. Релігійним святам офіційно протиставлялися нові радянські свята. Однак відсоток прихильників церковних обрядів вінчання, хрещення та поховання в середовищі титульної нації УРСР залишався досить високим. Релігійна активність представників українського етносу особливо прослідковувалася під час святкування Різдва, Водохреща, Великодня й інших церковних свят. І хоча кількість прибічників релігійних обрядів у республіці була різною – від меншої на Сході до більшої на Заході, проте християнські цінності всупереч атеїзації продовжували залишатися основою духовного життя абсолютної більшості українців.
Factors of Pension Funds' Growth: An Empirical Analysis of Egyptian Pension Funds
Authors: Qayyum Arslan , Arslan Aniqa , Ayubi Sharique
Published: June 2023

The goal of this research is to analyse the elements (corporate governance, regulatory framework, operational efficiency, investment strategy, and ethics) that affect pension funds and their ability to grow. The large asset base of the Egyptian financial sector can be better understood by reading this research.Principal component analysis was used to identify the key micro-factors that contributed to the increasing size of the pension fund. Later, the R2-change was examined as part of a hierarchical regression technique to examine the relative importance of each variable in the model. The examination of the data shows that all of the identified parameters, with the exception of fund restrictions in the final model, have a strong positive and substantial link with the growth of pension funds. Capital Market Board and Finance Ministry could benefit practically from the paper's methodology when making decisions about pension fund management and the fundamental factors underlying it. The study's micro-factors are drawn from a literature review of previous studies conducted in a variety of economies. This opens up the possibility of using the research as a basis for a comparative examination of pension fund growth across economies.
Göbeklitepe’nin sosyal medyadaki yansımaları: turistlerin çevrimiçi olumsuz yorumlarının içerik analizi
Authors: KUZU Sevgi , SÜRME Metin
Published: June 2023

Teknolojik gelişmelerde yaşanan yeniliklerle birlikte turizmde, turistik ürün seçiminde internet ağlarının kolay ulaşılabilir bir bilgi kaynağı haline gelmesi, insanların fikir ve görüşlerini yansıtabilecekleri bir ortam oluşmasına olanak sağlamıştır. Tüketicilerin paylaşımları, bireylerin tercihleri ve karar almalarında önemli bir etkiye sahiptir. Araştırmada amaç, Göbeklitepe’ye yapılan ziyaretlerde, misafirlerin olumsuz yorumlarının incelenmesi sonucunda yapılması gereken düzenlemeleri belirlemek ve alınması gereken önlemlerin neler olduğuna cevap bulmaya çalışmaktır. Bu kapsamda, Göbeklitepe ile ilgili 2019-2022 yılları arasında Tripadvisor sitesinde bulunan 59 olumsuz yorum içerik analiziyle incelenmiştir. Veriler MAXQDA programı ile değerlendirilmiştir. Araştırma sonucunda olumsuz yorumlarda öne çıkan, turistlerin giriş ücretinin çok pahalı olduğunu ifade etmeleridir. Araç park sorunu, devam eden kazılardan dolayı gezilecek alanın kısıtlı olması, görevlilerin ilgisizliği ve sorumluluklarını yerine getirmemeleri, engelli ve çocuklu ailelere göre bir düzenlemenin olmaması da yakınılan durumlar arasındadır. Değerlendirme sonuçlarından yola çıkılarak olumsuz yorumların belirlenerek iyileştirilmesine yönelik düzenlemeler ve birtakım önerilerde bulunulmuştur.
THE INITIAL PERIOD OF THE FORMATION OF THE COMPOSER PIANO SCHOOL IN CHINA
Authors:   Altai State Institute of Culture, Lun J. , Zhernosenko I.A. ,   Altai State Institute of Culture
Published: June 2023

The article discusses the initial stage of the formation of the piano composer school in China in the 20th century. The western musical tradition, "imported" into the cultural context of China, which was beginning to revive after the Opium Wars, quickly gained popularity among the progressive circles of Chinese society. The first Chinese composers and enlighteners, Zhao Yuanzhen and Xiao Yumei, played a key role in integrating local features of Chinese musical culture into the western piano tradition, thus laying the foundations for the "Chinese style" in modern piano music in China. The methodological basis of the study is a historical-cultural approach, which allowed us to identify the specific conditions for the emergence of a new direction in the development of Chinese musical culture in the 20th century. Based on musicological analysis, expressive features of the musical language in the works of the first Chinese composers who incorporated the piano into Chinese musical culture were identified: a close connection between melody and the phonological features and tonal specificity of Chinese speech in Zhao Yuanzhen's works, and the combination of the national pentatonic scale with western expressive means in Xiao Yumei's piano music.
FORMATION OF HISTORICAL MEMORY: WORLDVIEW ASPECTS
Authors:   Samara University of Public Administration «International Market Institute» (MIR University), Simashenkov P.D. , Suleymanova M.N. ,   Samara University of Public Administration «International Market Institute» (MIR University)
Published: June 2023

The article attempts to rethink the Russian historiosophical heritage, which, according to the authors, can ensure the development of science in an original way. The purpose of the study is to clarify the national "coordinate system of historical time", the task is to identify the peculiarities of the interpretation of the past and the present in the Russian tradition. Historical and moral progress is based on a sense of mis(matching) of contemporaries to their ancestors, heroized in memories and legends. Development is unthinkable without continuity, but it should be the continuity of creativity, not causality. The authors are convinced that only this method will ensure progress without interrupting the connection of time and thereby ensuring historical responsibility.
Renal function in patients with heart failure — a predictor for selecting RAAS inhibitors
Authors:   M.F. Vladimirskiy Moscow Regional Research and Clinical Institute, Moscow, Russian Federation, Khadzegova A.B.
Published: June 2023

Over the last few years, there has been an increasing trend in the prevalence of chronic kidney diseases (CKD) in patients with chronic heart failure (CHF). CKD is a well-known comorbidity in chronic heart failure, associated with lower survival rates, while cardiovascular complications are the leading cause of death among patients with CKD. The ability to identify early CKD in patients with CHF is critical for estimating prognosis, developing treatment strategy and tactics, and ultimately for preventing cardiovascular and renal complications. Considering the CKD prevalence in CHF, it is important to develop strategies for the administration of renin-angiotensin-aldosterone system inhibitors in view of their nephroprotective action with antiproteinuric and antiproliferative effects that can be also associated with improved survival. An angiotensin converting enzyme inhibitor such as fosinopril appears particularly beneficial for the treatment of CHF patients. Fosinopril undergoes enzymatic hydrolysis primarily in the liver and gastrointestinal mucosa and is converted to fosinoprilat which is eliminated equally by the kidneys and liver. In patients with renal dysfunction, the decreased fosinoprilat elimination with urine is compensated by the increased hepatic metabolism. Fosinoprilat exhibits less accumulation than enalapril or lisinopril in patients with CDK. KEYWORDS: chronic heart failure, renal function, chronic kidney disease, fosinopril, fosinoprilat, nephroprotection. FOR CITATION: Khadzegova A.B. Renal function in patients with heart failure — a predictor for selecting RAAS inhibitors. Russian Medical Inquiry. 2023;7(1):30–35 (in Russ.). DOI: 10.32364/2587-6821-2023-7-1-30-35.
Metabolic neuroprotection in patient with chronic heart failure: a case report and study results
Authors:   Pirogov Russian National Research Medical University, Moscow, Russian Federation, Reznik E.V. ,   City Clinical Hospital No. 31, Moscow, Russian Federation, Alieva A.M. ,   Pirogov Russian National Research Medical University, Moscow, Russian Federation, Ushakova N.A. ,   Pirogov Russian National Research Medical University, Moscow, Russian Federation, Krupnova E.S. ,   Pirogov Russian National Research Medical University, Moscow, Russian Federation
Published: June 2023

Cardiovascular diseases (CVD) are the leading cause of global mortality. The relative burden of acute forms of coronary heart disease (CHD) is gradually decreasing in the industrially developed countries, while the prevalence of chronic heart failure (CHF) and the number of hospitalizations of patients with CHF, on the contrary, has demonstrated an upward trend over the last decades. This retrospective analysis was performed to evaluate the data of patients with CHF decompensation. In such patients, cardiogenic encephalopathy (CE) was found in 43.4% of cases. A higher frequency and longer duration of hospitalizations was observed in the group of patients with CE. Also, in patients with CE the mortality rate within two years from the date of index hospitalization was twice as high as in patients without CE. For intensifying the major therapeutic options in the treatment of CHF patients with CE, it is feasible to consider the addition of numerous medications with supplementary pharmacological effects which may potentiate the efficacy of cardiotropic therapy. Among metabolically active drugs, an emphasis should be made on myocardial cytoprotectors. The results of several studies have provided persuasive data supporting the use of cytoprotectors in routine cardiological practice. This article describes a clinical case of using ethylmethylhydroxypyridine succinate for the treatment of an elderly patient with cardiogenic encephalopathy (CE) and presents the data proving the efficacy of this drug as a part of the combined symptomatic and pathogenetic therapy administered to patients with chronic cerebral ischemia amid CHD and CHF. KEYWORDS: cardiovascular diseases, ischemic heart disease, chronic heart failure, cardiogenic encephalopathy, cytoprotection, ethylmethylhydroxypyridine succinate, cardiotropic therapy. FOR CITATION: Reznik E.V., Alieva A.M., Ushakova N.A., Krupnova E.S. Metabolic neuroprotection in patient with chronic heart failure: a case report and study results. Russian Medical Inquiry. 2023;7(1):49–55 (in Russ.). DOI: 10.32364/2587-6821-2023-7-1-49-55.
Individual’s Adaptive Processes: Rephrasing in Terms of Inflammation
Authors: Actis Giovanni C , Ribaldone Davide G
Published: June 2023

Inflammation, one among the evolutionary driving forces, is now acknowledged under two subheadings, depending on whether the individual immune system has been educated under the pressure of nature’s physiologic stressors, or under man-made artificial drifts. In the former case, the reaction is demarcated and self-resolving, at the expense of possible host death. In the latter, the evolution is chronic, sparing subject’s life at the expense of chronic multi-organ inflammatory disease. There is now evidence that this disorder is reaching epidemics-like proportions. Adaptation with immunologic down grading and tolerance may be the way to individual’s survival. We analyze the literature that in our own arbitrary opinion supports this view, including a final proof-of concept based on human volunteer data elaboration.
The effect of heat treatment of starch on its crystal structure and dynamic viscosity of starch pastes
Authors:   Ukrainian State University of Chemical Technology, Myrhorodska-Terentieva V.D. , Nikolenko M.V. ,   Ukrainian State University of Chemical Technology, Bukhal K.O. ,   Ukrainian State University of Chemical Technology, Avdiienko T.M. ,   Ukrainian State University of Chemical Technology
Published: June 2023

Analysis of literature data shows the uncertainty of a number of issues of the starch dextrinization process, namely the patterns of the change in the crystal structure of starch during heat treatment and the dependence of the viscosity of starch pastes of dextrins on the conditions of starch heat treatment. These questions were chosen as the topic of this study. A decrease in the average size of starch particles by 2.7 m and an increase in the intensity of reflexes of diffractograms in the range of 2=10–200 after its heat treatment at 1350C (the temperature at which the dextrinization process starts) are well explained by dehydration and a change in the degree of crystallization of biopolymer macromolecules due to their thermal transformations. The dependence of the dynamic viscosity of hot pastes on their shear rate was studied. The steady shear flow curves showed the presence of dilatant areas as a transition from the Newtonian flow regime to the pseudoplastic flow of starch pastes. It was found that the viscosities of heat-treated starch pastes depend on the processing conditions; the viscosities increase in the following order: starch heat-treated in the presence of an acid catalyst; native starch; starch heat-treated without a catalyst for 5 hours; and starch heat-treated without a catalyst for 2.5 hours. It was proposed to divide dextrins into two separate groups: with an increased and with a reduced degree of amylose polymerization.
New spectrophotometric method for estimation of losartan potassium using Alizarin Red reagent
Authors:   Department of Chemistry, Education College for Girls, University of Mosul, Al-Mashadani Asmaa H. , Mohammed Dawood H. ,   Department of Chemistry, Education College for Girls, University of Mosul
Published: June 2023

A simple, rapid, precise, and sensitive analytical method has been developed to identify losartan potassium in its pure and pharmaceutical dosage forms. This method involves a proton transfer between the losartan reagent and the Alizarin Red reagent in an acidic medium while standing to complete the reaction to obtain a colored product bound to the amount of losartan potassium, this product having a maximum absorption at 493 nm. A linear calibration curve was obtained over a concentration range of 1.5–12.5 gml–1 with a correlation coefficient of 0.9991. The molar absorptivity was 4.522104 lmol–1cm–1, and Sandell's sensitivity index was equal to 0.010 gcm–2. The limit of detection (LOD) and quantification (LOQ) values were 0.359 and 1.121 gml–1, respectively. The suggested approach was applied to estimate losartan potassium in the available pharmaceutical preparations (tablets). The results confirmed that the technique is successful by studying the recovery using the standard addition method.
On ways of conversion of silicon dioxide SiO2 in lithium battery systems: a review
Authors:   Ukrainian State University of Chemical Technology, Apostolova R.D. , Shembel E.M.
Published: June 2023

Silicon and silicon oxide compounds SiO, SiO2, SiOx and SiOC are considered as a promising family of materials for high-energy lithium batteries due to their high theoretical capacity, widespread in nature, low cost, environmental safety and ease of synthesis. Silicon oxide compounds have replaced silicon in the hope of improving the discharge characteristics of lithium batteries. Oxides of silicon show excellent stability during cycling after structure optimization. However, they suffer from the problem of low Coulomb efficiency and high voltage hysteresis (difference in charge and discharge voltage), which prevents their practical application. Significant bulk expansion of silicon oxides during cycling and irreversible loss of capacity in the initial cycles are an obstacle to their large-scale practical use. This review pays attention to the peculiarities of the conversion of SiO2 and its hybrid compounds into the redox reaction with lithium and ways to overcome existing problems. Silicon dioxide is more resistant to bulk expansion than silicon. Various structural formats of nanometer SiO2 have been developed and tested for lithium batteries, such as nanotubes, nanorods, nanowires, nanoparticles, thin films. To solve problems in the SiO2/Li system, a number of SiO2 composites with carbon, graphene, active and inactive metals, etc. have also been proposed and studied. Analyzing the results of the studies, we found a significant role of the solid electrolyte interphase film in the efficient conversion of SiO2. In turn, the formation of a film on silicon dioxide depends on the method of synthesis of dioxide, which introduces impurities into the final synthesis product. Impurities contribute to the distortion of the solid electrolyte interphase film during the cycling of the SiO2/Li system, and the loss of discharge capacity. SiO2 dioxide obtained in a dry environment of a ball mill differs favorably from that obtained from solutions. Many efforts have been made to overcome the problems in Si-containing electrode materials, however, they have to go a certain way for large-scale practical application.
Iminophenol as a ligand or cation in cobalt(II and II,III) complexes: synthetic approaches, spectral and structural studies
Authors:   Taras Shevchenko National University of Kyiv, Vassilyeva O.Yu. , Kokozay V.N. ,   Taras Shevchenko National University of Kyiv, Skelton B.W. ,   University of Western Australia
Published: June 2023

New complexes [H2L]2CoCl4 (І) and [CoІІCоІІІCl2L3]H2O (ІІ), where HL is a condensation product of o-vanillin and methylamine, were synthesized and characterized by IR, UV/Vis spectroscopies, and X-ray structural analysis. For the synthesis of I, cobalt (II) chloride was used as a metal source, while for II, cobalt powder and its salt were used simultaneously. In the preparation of I, the use of methylamine hydrochloride contributed to the formation of tetrachlorocobaltate(II) with the protonated Schiff base H2L+as a cation. The monovalent cations are almost planar and show the presence of intramolecular O/N–HО hydrogen bonds. In the crystal, columns of cations connected by - stacking alternate with double-row columns of tetrahedral [CoCl4]2– anions and are additionally joined by a branched system of O/N–HCl hydrogen bonds. Crystal II is built of neutral molecules CoІІСоІІІCl2L3 and uncoordinated water molecules. In the molecule, the main CoІІІL3 fragment with a metal atom in the octahedral environment of three deprotonated ligands attaches a cobalt(II) atom at the CoIICoIII distance of 3.17 Å. The cobalt(II) atom has a highly distorted five-coordinate СоІІО3Cl2 environment formed by two bridging oxygen atoms of deprotonated phenoxy groups, the O atom of the methoxy group of the ligands, and two chlorine atoms. The obtained results allow us to propose the use of the metal salt+its powder combination for the purposeful synthesis of mixed-valent complexes of metals capable of exhibiting various oxidation states. Deliberate protonation of the Schiff base can be used to prepare organic-inorganic metal halide hybrids with functionalized cations.
Conformational transformation of N-[arylsulfonylimino(phenyl)methyl]-1,4-benzoquinonemonoimines
Authors:   Donbass State Engineering Academy, Konovalova S.A. , Avdeenko A.P. , Pirozhenko V.V. , Goncharova S.A.
Published: June 2023

It was established that in the solutions of N-[arylsulfonylimino(phenyl)methyl]-1,4-benzoquinonemonoimines there are both Z,E-isomerization relative to C=N bonds and atropoisomerism (inhibited rotation around the =N1–C= bond). The latter can be detected when there are the diastereotopic isopropyl groups in the quinoid ring. The rate constants of this process were calculated by the method of analysis of the full line in the 1H NMR spectra. Activation thermodynamic parameters were determined on their basis. With the help of quantum-chemical calculations, we proved that the determined experimental barriers corresponded exactly to the inhibited rotation around the bond =N1–C=.
Using the method of calculating the total molar energy of cohesion to choose the most effective plasticizer
Authors:   Ukrainian State University of Chemical Technology, Kuzmenko M.Ya. , Sporyagin E.O. , Kuzmenko O.M. , Filinska T.G. , Filinska А.О.
Published: June 2023

It is known that products made of polar, crystallized, and high-strength polymers (polyamides, polyesters, cellulose triacetate, polyvinyl chloride, etc.) lose their initial properties that reduce reliability and durability in the process of operation and even during long-term storage due to the increase in internal stresses in them caused by crystallization processes over time. To reduce the impact of such processes on the properties of polymer products, special substances are introduced into their composition, plasticizers, the selection of which is usually carried out empirically, which is not always successful. We proposed in this study to use the ratio of the calculated total molar volumetric energy of cohesion of the compound (the cumulative interaction of interatomic and intermolecular forces in the composition of the compound) to its molecular weight as the specific mass total energy of cohesion, which can be compared with a similar indicator for a plasticizing polymer. The use of such an approach makes it possible to purposefully, even before experimental verification, evaluate the suitability of using this or that compound, oligomer, or polymer as a plasticizer (or modifier), or develop a molecular structure of a new, necessary compound with the inclusion of certain groups in its composition for the purpose of further use as a plasticizer or modifier. In addition, there is an opportunity to monitor the influence of individual structural components of a new compound, oligomer or polymer, its molecular weight, side substituents and their nature on the value of the specific mass total energy of cohesion, as well as to reduce the time for performing research works in this direction and expenses for their implementation.
À propos de quelques Bibionidés boréo-alpins, dont Bibio brunnipes (Fabricius, 1794), espèce nouvelle pour la faune de France (Diptera, Bibionidae)
Authors: Haenni Jean-Paul , Combrisson Damien , Claude Jocelyn
Published: June 2023

Note about some boreo-alpine March-flies, with special reference to Bibio brunnipes (Fabricius, 1794), new species for the fauna of France (Diptera, Bibionidae). The presence in France of the boreo-alpine species Bibio brunnipes (Fabricius, 1794) is ascertained for the first time from localities in department Hautes-Alpes, at altitudes of 2300-2480 m. A preceding record of the species from a low altitude locality is discarded, as it is based on a wrong identification. The presence of the species in Hungary, based on a wrong attribution of locality, is discarded. A new locality in the Alpes-de-Haute-Provence is given for the rarely observed B. lautaretensis Villeneuve, 1924. The situation in France of B. brunnipes, B. lautaretensis and a third boreo-alpine bibionid, Dilophus borealis Skartveit, 1993, is discussed.
First record of the genus Heterostylum Macquart, 1848, in the Lesser Antilles (Diptera, Bombyliidae)
Authors: Dumbardon-Martial Eddy , Einicker Lamas Carlos José
Published: June 2023

Premier signalement du genre Heterostylum Macquart, 1848, dans les Petites Antilles (Diptera, Bombyliidae). Le genre Heterostylum Macquart, 1848, est signalé pour la première fois des Petites Antilles suite à la découverte d’Heterostylum ferrugineum dans les îles de Martinique, Guadeloupe et Saint-Barthélemy. Un unique spécimen fut collecté pour la première fois en Martinique en 1953 par le Père Pinchon (1913-1980), puis quatre autres au cours d’une récente campagne d’inventaire entomologique des Zones Naturelles d’Intérêt Écologique, Faunistique et Floristique (ZNIEFF). Il s’avère que l’espèce est inféodée aux habitats forestiers xérophiles de la presqu’île de la Caravelle. Sa présence dans les autres îles est attestée par des observations de naturalistes sans qu’aucun spécimen n’ait été conservé.
Penggunaan Metode Importance-Performance Analysis (IPA) Untuk Menganalisis Kepuasan Masyarakat Terhadap Pelayanan Administrasi Kependudukan
Authors: Wisudawati Nidya , Irfani Muhammad Ghozi , Hastarina Merisha , Santoso Budi
Published: June 2023

Penelitian ini dilakukan dengan tujuan untuk mengetahui tingkat kepuasan masyarakat di Kecamatan Lengkiti, Ogan Komering Ulu, Sumatera Selatan. Adapun pelayanan yang diberikan yaitu administrasi kependudukan dan lainnya yang  berkaitan dengan pemerintahan ditingkat Kecamatan. Namun masih terdapat beberapa keluhan yang dirasakan oleh masyarakat antara lain yaitu birokrasi yang berbelit-belit, informasi yang diberikan petugas sulit dipahami masyrakat, dan petugas sering datang terlambat. Penelitian ini dilakukan dengan menyebarkan 86 kuesioner dan pengolahan data dilakukan dengan metode Importance Performance Analysis (IPA). Metode Importance Performance Analysis (IPA) bertujuan untuk mengetahui nilai tingkat kesesuaian antara tingkat ekspektasi dan persepsi yang kemudian dilakukan plotting dengan menggunakan diagram kartesius. Dari hasil perhitungan Importance Performance Analysis (IPA) memiliki nilai tingkat kesesuaian 91% dan pada diagram kartesius dari 25 atribut, terdapat 8 atribut yang memerlukan perbaikan dan peningkatan yaitu atribut nomor 2,7,9,12,15,16,18,21. Akan tetapi perlu adanya perbaikan di beberapa atribut pernyataan karena dirasa masih terdapat kekurangan terutama penyampaian informasi lebih mudah dipahami dan adanya standar pelayanan yang baik. This study was aimed to determine the level of community satisfaction in Lengkiti District, Ogan Komering Ulu, South Sumatra. The services provided are population administration and others related to the Government at the sub-district level. However, there are still some complaints that are felt by the community. These complaints include convoluted bureaucracy, information provided by officials is difficult for the public to understand, and officers often arrive late. This research was conducted by distributing 86 questionnaires and calculations were carried out using the Importance Performance Analysis (IPA) method. The Importance Performance Analysis (IPA) method aims to determine the value of the level of concordance between the level of expectations and perceptions which is then plotted using a Cartesian diagram. From the results of the Importance Performance Analysis (IPA) calculation, it has a suitability level of 91% and on the Cartesian diagram of 25 attributes, there are 8 attributes that require repair and improvement, namely attribute numbers 2,7,9,12,15,16,18,21. However, it is necessary to improve some of the statement attributes because it is felt that there are still shortcomings, especially in conveying information that is easier to understand and there is a good service standard.