bluuebunny/crossref_metadata_2025 huggingface dataset:
Evangelisasi dan Pendidikan Agama Kristen: Pendidikan Minat dan Pemahaman Injil Generasi Milenial Pantekosta
Authors: Sembiring Hesra Oktavianus , Tambunan Elia , Sudjono Andreas
Published: May 2023

Tren gereja dunia pasa saat ini berada dalam krisis generasi milenial yang melarikan diri dari gereja, tulisan ini justru menampilkan pendidikan minat dan pemahaman Injil bagi generasi milenial Pantekosta agar terlibat evangelisasi dengan cara meneladani Yesus. Penelitian dilakukan dengan pendekatan kuantitatif. Data dikumpulkan lewat kuesioner dengan skala Likert, dianalisis dengan korelasi Pearson Product Moment memakai rumus statistik nilai Confidence Interval Lower and Upper Bound. Lokus penelitian Sekolah Tinggi Teologi Salatiga, Jawa Tengah, dan responden adalah mahasiswa tahun 2018-2020 sebanyak 65 orang semester 4 dan 6 yang telah menempuh mata kuliah Tafsir Injil Yohanes 4:1-42 dan Praktik Penginjilan. Temuan memperlihatkan bahwa upaya-upaya pembelajaran doktrinal oleh dosen baik itu akademis dan non akademis maupun kultur kelembagaan mendukung semakin terbentuknya praksis pendidikan tinggi keagamaan Kristen. Tulisan ini menyodorkan kerangka konseptual baru, yakni pendidikan minat dan pemahaman, untuk ilmu pedagogi misi di Pendidikan Agama Kristen maupun teologi misi di program studi Teologi.
Implementasi Firman Tuhan dalam Mewujudkan Pendidikan Pluralisme Bagi Sekolah Minggu: Sebuah Kajian Pendidikan Agama Kristen
Authors: Simanjuntak Elista
Published: May 2023

Penelitian ini dilatarbelakangi adanya konflik pembongkaran dan pembakaran gereja pada Huria Kristen Indonesia Suka Makmur di Aceh Singkil. Tujuan utama dari penelitian ini adalah untuk memberi edukasi bahwa Sekolah Minggu sebagai lembaga pendidikan Kristen yang mengajarkan dan melatih anak untuk mengalami pertumbuhan iman yang benar kepada Yesus serta mengajarkan tentang cara bersikap terbuka dan menerima setiap perbedaan yang ada, dalam hal agama, suku, ras, dan lains sebagainya. Adapun metode yang digunakan dalam penelitian ini adalah kualitatif deskriptif dengan menggambarkan Alkitab dan implementasinya dalam mewujudkan pendidikan pluralisme bagi Sekolah Minggu. Adapun hasil penelitian menunjukkan bahwa Alkitab sebagai esensi wujud pembentukan karakter pluralisme anak sejak usia dini ditengah keberagaman yang dapat diterapkan melalui ranah pendidikan lembaga Sekolah Minggu dengan mendasarkan bahwa Alkitab sebagai fundamentalisme keberagaman. Selain itu, Alkitab juga sebagai sumber legitimasi pengajaranhakikat pendidikan pluralisme dalam Sekolah Minggu.
INSTALASI RUNNING TEXT SEBAGAI ALAT BANTU INFORMASI DALAM RANGKA MENARIK MINAT BACA DI DESA JAYASAKTI
Authors: Alfado Muhammad , Lubis Rabianur , Azhari Adli
Published: May 2023

The Real Work Lecture Program (KKN) for installing running text as an information aid in order to attract reading interest in Jayasakti village has been implemented. The aim of this program is to increase the reading interest of the people in Jayasakti village through the use of information aids in the form of running texts. The method used in this program is the observation method in the form of data collection, making running texts, and installing running texts in Jayasakti village. The result of this running text installation program is the creation of an interesting atmosphere for people in Jayasakti village to read the information displayed through running text. In addition, this program has also succeeded in increasing the reading interest of the Jayasakti village community. Thus, this program can be used as an effort to increase interest in reading in other villages.
PELATIHAN PEMANFAATAN BARANG BEKAS SEBAGAI MEDIA PEMBELAJARAN
Authors: Oktapiani Nabila Mega , Budianti Yudi , Rikmasari Rima
Published: May 2023

Garbage is material that is disposed of by humans and is not used. Garbage is a very big problem, besides having a sale value, trash or used goods can be used to make learning media that are very useful for the learning process. Learning media is one of the tools used by teachers and functions to stimulate the mind, attention, and motivation to learn in students. The implementation method using community education and training methods aims to increase teacher creativity and can reduce waste pollution in Lennggajaya Village. The results of the service prove that learning media can help students' thinking processes become faster and easier to understand, arouse student motivation and teaching methods will be more varied. Based on the results of this evaluation, it can have an impact on reducing the accumulation of waste in Leggahjaya Village. By utilizing used goods in the surrounding environment, it can help in terms of waste management and using used goods as learning media in elementary schools, so it will directly save costs in making media in schools.
PENERAPAN WEBSITE DESA SEBAGAI MEDIA INFORMASI PENGENALAN POTENSI DESA SUMBEREJA
Authors: Sya'bana Salwa Ibnatisna , Berry Yunike , Rusham Rusham
Published: May 2023

The progress of information technology is closely linked to the digital and informatics fields. It has become an integral part of people's lives, from using mobile phones to accessing the internet with its various features and functions. The impact of information technology is not limited to urban areas, as it has also reached rural areas. For instance, Sumbereja village still uses manual methods to gather information. This situation inspired the author to create a website for Sumbereja village, which would enable the wider community to gain a better understanding of the village through the web. To address this issue, the Real Work Lecture Activities of Islamic University 45 Bekasi proposed a work program. The program aimed to create an "Application of Village Website as a Medium of Information to Introduce the Potential of Sumbereja Village, Pebayuran District." This service activity focused on developing a village profile website, which would serve as the main source of village information. The data collection process involved documentation, surveys, and interviews with village officials to provide comprehensive information. The primary objective of this initiative was to provide information to the community and assist village officials in delivering public services that could be easily accessed by the public.
IMPLEMENTASI PEMASARAN DIGITAL DALAM MENINGKATKAN PENDAPATAN PELAKU UMKM DESA PANTAI MEKAR
Authors: Erlianalistiani Erlianalistiani , Rahmawati Rafika , Marginingsih Ria
Published: May 2023

Digital marketing implemented by MSMEs in Pantai Mekar Village is based on market segmentation, target market, and positioning for the lower middle class, upper middle class because the prices given are cheaper than the general market price. The obstacles that occur in MSMEs are the lack of promotion in marketing their products, the lack of effective and efficient promotion and not carrying out digital promotions. The purpose of implementing this community service is to assist business actors in providing Digital-Based Online Marketing Training to Increase Online Business Sales for MSMEs in Pantai Mekar Village, Muara Gembong District, Bekasi Regency. The method of community service activities begins with the stages of preparation and field surveys. The implementation of community service is divided into three activities, namely digital marketing training for MSMEs, training on how to create digital content through workshops and practices, and evaluation of the training that has been carried out. The result of community service related to digital marketing is to become a forum and means of education and add insight to MSMEs regarding the use and utilization of digital marketing.
PELATIHAN TEKNIK HIDROPONIK SEDERHANA UPAYA PENGEMBANGAN LAHAN TIDUR MENJADI LAHAN PRODUKTIF DI DESA KARANGREJA
Authors: Husaini Abdul Azis , Paryati Ninik , Susanti Neneng Lasmita
Published: May 2023

Land utilization for large industries is usually used as a form of large economic practices that involve a lot of production costs. But for a village, utilizing existing land will be a great help that does not require large costs. Utilizing simple land around the house or neighborhood will get many benefits, especially small cost benefits. Many residents have not been able to utilize the land around the environment to become productive land that produces profits. Therefore, the method used is to conduct training to residents who do not understand to utilize their narrow land into economically productive land with simple equipment. The result of the implementation of a simple hydroponic training program in an effort to develop idle land is that the head of Karangreja Village requested that hydroponics be made in the village as an example for the wider community who want to follow the example of hydroponics with the DFT method.
HIF-1 Sensor in Detecting Hypoxia Tolerance at High Altitude
Authors: Shaharuddin Shazreen , Nik Abd Rahman Nik Mohd Afizan , Masarudin Mas Jaffri , Alamassi Mohammedarfat N. , Ahmad Saad Fathinul FikrI
Published: May 2023

INTRODUCTION: An episode of prolonged exposure to high altitude can cause hypoxia and have significant health consequences. In people with a high-altitude disorder, the body reacts by producing a protein called hypoxia-inducible factor (HIF), which triggers a series of physiological
changes and serves a central role in the hypoxia response. Its activity is regulated by the oxygen-dependent degradation of the HIF-1α protein (HIF-1A gene). Therefore, the effects of low oxygen tension in high altitude were explored using fluorescent sensors of hypoxia.METHODS:
The development of the sensor provided more sensitivity for detecting hypoxia by generating a calibration of optimized parameters such as reagent concentrations, reagent volumes, and device dimensions.RESULTS: There is a high sensitivity and specificity in detecting the changes
of HIF-1α protein hypoxia using the feasibility hypoxia test. This would enable point-of-care (POC) testing and individual self-administration, resulting in faster and more accurate results that can be used for a robust diagnostic approach and enhanced health surveillance, particularly
in high-altitude exposure.Shaharuddin S, Rahman NMANA, Masarudin MJ, Alamassi MN, Saad FFA. HIF-1 sensor in detecting hypoxia tolerance at high altitude. Aerosp Med Hum Perform. 2023; 94(6):485–487.
A Comprehensive Look Behind Team Composition for Long Duration Spaceflight
Authors: Gangeme Alexis , Simpson Benjamin , De La Torre Gabriel G. , Larose Tricia L. , Diaz-Artiles Ana
Published: May 2023

BACKGROUND: How to determine team composition is one of many key topics when developing humanity’s next deep space exploration programs. Behavioral health and performance among spaceflight teams are key aspects impacted by team composition and cohesiveness.METHODS:
This narrative review highlights areas of consideration for building cohesive teams in long duration spaceflight environments. The authors gathered information from a variety of team-behavior related studies that focused on team composition, cohesion, and dynamics, as well as others topics
such as faultlines and subgroups, diversity, personality traits, personal values, and crew compatibility training.RESULTS: The literature suggests that team cohesion occurs more easily when individuals are similar to one another, and deep-level variables such as personality and
personal values have a greater impact on crew compatibility than surface level variables such as age, nationality, or gender. Diversity can have both positive and negative impacts on team cohesiveness.CONCLUSION: Team composition, as well as pre-mission conflict resolution training
can greatly impact group cohesion. This review aims to map areas of concern and assist with crew planning for long duration spaceflight missions.Gangeme A, Simpson B, De La Torre GG, Larose TL, Diaz-Artiles A. A comprehensive look behind team composition for long duration spaceflight.
Aerosp Med Hum Perform. 2023; 94(6):457–465.
Human Physiological Limitations to Long-Term Spaceflight and Living in Space
Authors: H. Winkler Lawrence
Published: May 2023

INTRODUCTION: Despite all our dreams and enthusiasm, the essential question of whether our species can ever live permanently in space remains unanswered. The 1975 NASA Ames Design Study on Space Settlements demonstrated how human physiology constrains and determines human habitat
design in space. Our scientific understanding about the risks of and standards for microgravity (and rotation rate if centrifugally generated), ionizing radiation, and atmosphere pressure and composition, remains inadequate a half century later. In addition, there are newly recognized physiological
challenges to living safely in space, including spaceflight-associated neuro-ocular syndrome (SANS), extravascular hemolytic anemia, and other factors that affect every human cell and organ system. A comprehensive review was conducted to establish what we have learned and what is still required
to know about the pathophysiology of long-term space travel and living in space since my first report in 1978. The results determine not only how, but if we can realistically plan to inhabit the cosmos that surrounds us.Winkler LH. Human physiological limitations to long-term spaceflight
and living in space. Aerosp Med Hum Perform. 2023; 94(6):444–456.
Pilots’ Spatial Visualization Ability Assessment Based on Virtual Reality
Authors: Zhang Mengdi , Wang Meng , Feng Huimin , Liu Xunyuan , Zhai Lihong , Xu Xianrong , Jin Zhanguo
Published: May 2023

BACKGROUND: The aim of this study was to investigate the effectiveness of the mental rotation test (MRT) based on virtual reality (VR) in predicting pilots’ spatial visualization ability (SVA).METHODS: Based on VR, 118 healthy pilots’ SVA were evaluated
by MRT. The pilot flight ability evaluation scale was used as the criterion of test validity. According to the scale score, pilots were divided into high, middle, or low spatial ability groups pursuant to the 27% allocation principle. Differences in reaction time (RT), correct rate (CR), and
correct number per second (CNPS) of MRT between groups were compared. Correlations between scale scores and MRT scores were analyzed. RT, CR, and CNPS of MRT among different age groups and between genders were also compared.RESULTS: The RT of the high spatial ability group was remarkably
slower than that of the low spatial ability group (363.4 ± 140.2 s, 458.1 ± 151.7 s). The CNPS of the high spatial ability group was dramatically higher than that of the low spatial ability group (0.111 ± 0.045 s,
0.086 ± 0.001 s). There were no significant differences in RT, CR, and CNPS between different genders. Pilots in the 29–35 yr old age group had considerably slower RT than those in the 22–28 yr old age group (330.8 ± 140.3 s,
417.2 ± 132.7 s). Pilots in the 29–35 yr old age group had conspicuously higher CNPS than pilots in the 22–28 yr old age group (0.119 ± 0.040 s, 0.096 ± 0.036 s). All pilots’
scale scores were positively correlated with CNPS (r = 0.254) and negatively correlated with RT (r = -0.234).DISCUSSION: MRT based on VR has a good discrimination efficacy for SVA of pilots and is a good indicator for the SVA component measurement.Zhang M, Wang
M, Feng H, Liu X, Zhai L, Xu X, Jin Z. Pilots’ spatial visualization ability assessment based on virtual reality. Aerosp Med Hum Perform. 2023; 94(6):422–428.
Ḥamza's Consideration of Ibn Masʿūd's Divergent Readings
Authors: Albakri Redwan B. Refat
Published: May 2023

This study deals with the issue of Imām Ḥamza al-Zayyāt al-Kūfī – one of the seven reciters – and his acceptance of the reading of Ibn Masʿūd when it diverges from the muṣḥaf of ʿUthmān, so as to shed light on the early history of Qur’anic qirāʾāt. The article explores the ways in which Ḥamza was impacted by Ibn Masʿūd’s recitation, and the extent to which he followed it or implemented his own innovations, based on an applied study of the readings of Ibn Masʿūd that diverge from the ʿUthmanic codex as recorded in Ibn Abī Dāwūd’s al-Maṣāḥif and transmitted from al-Aʿmash. By comparing Ibn Masʿūd’s readings with the ten accepted qirāʾāt it seeks to analyse how close these recitations are to Ibn Masʿūd’s readings and to what extent they have been affected by them. This comparative analysis indicates that there is a strong relationship between the reading of Ḥamza and the recitations of Ibn Masʿūd, to an extent unseen in any of the other ten reciters. It reveals that, although Ḥamza does not follow all of Ibn Masʿūd’s readings, Ibn Masʿūd’s reading is clearly foundational to his recitation. The study concludes that Ḥamza’s use of Ibn Masʿūd’s readings indicates that he did not invent his own readings by opinion or ijtihād, while the fact he did not accept of all of Ibn Masʿūd’s readings testifies to the fact that he adhered only to what has been transmitted, and did not go beyond this to accept those of Ibn Masʿūd’s readings that were not.
Peace is worth paying for
Authors: J. Martin Terence
Published: May 2023

This essay examines the unsettling claim of Erasmus that “an unjust peace is preferable by far than a just war”—a dictum he retrieves from Cicero but applies to debates about warfare between nations, feuds of religion, and interpersonal conflicts. Embedded in this aphorism is an entire Erasmian ethic of conflict, one wherein he prods leaders and individuals to pay the price for peace by settling on less than desirable and possibly unfair terms, in order to avoid the devastating fallout of full-fledged battle, while preserving the life of nations, the good of a community, the unity of a church, or the welfare of a friendship. With that challenge Erasmus proceeds to unwind just war theory with its own methods, and he does so with a curious but provocative blend of the most ideal of aspirations with utterly realistic challenges of practical reasoning.
Latin particles in De Tristitia Christi: the fine-tuning of word choice
Authors: Cabrillana Concepción
Published: May 2023

This paper aims to identify and analyze some of the substitutions of the particle sed (> ceterum/verum/at), visible in the manuscript of More’s De Tristitia. In this study, the theoretical framework of Functional Discourse Grammar is applied for the first time, and it helps to explain some of the reasons underlying More’s final choices. One of the clearest conclusions is that More tries to show that the particle chosen does not function as a conjunction at the sentence level but as an adversative connector at the presentational level; this level has to do with the presentation and organization of the information in the text, and can serve to offer an explanation, justification, clarification, context, etc. between the various textual units. The examination of the passages in context also shows how More was careful to avoid repetitions which could diminish the elegance of the chosen linguistic expression.
Gay Bar: The Fabulous, True Story of a Daring Woman and Her Boys in the 1950s
Authors: Fellows Will , Branson Helen
Published: May 2023

Vivacious, unconventional, candid, and straight, Helen Branson operated a gay bar in Los Angeles in the 1950s—America’s most anti-gay decade. After years of fending off drunken passes as an entertainer in cocktail bars, this divorced grandmother preferred the wit, variety, and fun she found among homosexual men. Enjoying their companionship and deploring their plight, she gave her gay friends a place to socialize. Though at the time California statutes prohibited homosexuals from gathering in bars, Helen’s place was relaxed, suave, and remarkably safe from police raids and other anti-homosexual hazards. In 1957 she published her extraordinary memoir Gay Bar, the first book by a heterosexual to depict the lives of homosexuals with admiration, respect, and love. In this new edition of Gay Bar, Will Fellows interweaves Branson’s chapters with historical perspective provided through his own insightful commentary and excerpts gleaned from letters and essays appearing in gay publications of the period. Also included is the original introduction to the book by maverick 1950s psychiatrist Blanche Baker. The eclectic selection of voices gives the flavor of American life in that extraordinary age of anxiety, revealing how gay men saw themselves and their circumstances, and how others perceived them.
The Ice Cave: A Woman’s Adventures from the Mojave to the Antarctic
Authors: Bledsoe Jucy Jane
Published: May 2023

For Lucy Jane Bledsoe, wilderness had always been a source of peace. But during one disastrous solo trip in the wintry High Sierra she came face to face with a crisis: the wilderness no longer felt like home. The Ice Cave recounts Bledsoe’s wilderness journeys as she recovers her connection with the wild and discovers the meanings of fear and grace. These are Bledsoe’s gripping tales of fending off wolves in Alaska, encountering UFOs in the Colorado Desert, and searching for mountain lions in Berkeley. Her memorable story “The Breath of Seals” takes readers to Antarctica, the wildest continent on earth, where she camped out with geologists, biologists, and astrophysicists. These fresh and deeply personal narratives remind us what it means to be simply one member of one species, trying to find food and shelter—and moments of grace—on our planet.
Two Novels: Development and Two Selves
Authors: Bryher
Published: May 2023

Bryher (born Annie Winifred Ellerman) is perhaps best known today as the lifelong partner of the poet H.D. She was, however, a central figure in modernist and avant-garde cultural experimentation in the early twentieth century; a prolific producer of poetry, novels, autobiography, and criticism; and an intimate and patron of such modernist artists as Gertrude Stein, Marianne Moore, and Dorothy Richardson. Bryher’s own path-breaking writing has remained largely neglected, long out of print, and inaccessible to those interested in her oeuvre. Now, for the first time since their original publication in the early 1920s, two of Bryher’s pioneering works of fictionalized autobiography, titled Development and Two Selves, are reprinted in one volume for a new audience of readers, scholars, and critics.
The Pox Lover: An Activist's Decade in New York and Paris
Authors: d'Adesky Anne-christine
Published: May 2023

The Pox Lover is a personal history of the turbulent 1990s in New York City and Paris by a pioneering American AIDS journalist, lesbian activist, and daughter of French-Haitian elites. In an account that is by turns searing, hectic, and funny, Anne-christine d’Adesky remembers “the poxed generation” of AIDS—their lives, their battles, and their determination to find love and make art in the heartbreaking years before lifesaving protease drugs arrived.
My Son Wears Heels: One Mom's Journey from Clueless to Kickass
Authors: Tarney Julie
Published: May 2023

In 1992, Julie Tarney’s only child, Harry, told her, “Inside my head I’m a girl.” He was two years old. Julie had no idea what that meant. She felt disoriented. Wasn’t it her role to encourage and support her child? Surely, she had to set some limits to his self-expression—or did she? Would he be bullied? Could she do the right thing? What was the right thing? The internet was no help, because there was no internet. And there were zero books for a mom scrambling to understand a toddler who had definite ideas about his gender, regardless of how Nature had endowed him. Terms such as transgender, gender nonconforming, and gender creative were rare or nonexistent. There were, however, mainstream experts who theorized that a “sissy” boy was the result of a domineering mother. Julie couldn’t believe it. She didn’t want to care what her neighbors thought, but she did care. “Domineering mother” meant controlling mother. It meant bad mother. It meant her mother. Lacking a positive role model of her own, and fearful of being judged as a mom who was making her son “too feminine,” Julie embarked on an unexpected parenting path. Despite some missteps, and with no map to guide her, she learned to rely on her instincts. She listened carefully, kept an open mind, and as long as Harry was happy, she let him lead the way. Julie eventually realized that Harry knew who he was all along. Her job was simply to love and support him unconditionally, allowing him to be his authentic self. This story of a mother embracing her child’s uniqueness and her own will resonate with all families.
Body Blows: Six Performances
Authors: Miller Tim
Published: May 2023

Hailed for his humor and passion, the internationally acclaimed performance artist Tim Miller has delighted, shocked, and emboldened audiences all over the world. Body Blows gathers six of Miller’s best-known performances that chart the sexual, spiritual, and political topography of his identity as a gay man: Some Golden States, Stretch Marks, My Queer Body, Naked Breath, Fruit Cocktail, and Glory Box. In Body Blows, Tim Miller leaps from the stage to the page, as each performance script is illustrated with striking photographs and accompanied by Miller’s notes and comment. This book explores the tangible body blows—taken and given—of Miller’s life and times as explored in his performances: the queer-basher’s blow, the sweet blowing breath of a lover, the below-the-belt blow of HIV/AIDS, the psychic blows from a society that disrespects the humanity of lesbian and gay relationships. Miller’s performances are full of the put-up-your-dukes and stand-your-ground of such day-to-day blows that make up being gay in America.
Self-Made Woman: A Memoir
Authors: DuBois Denise Cnanterelle
Published: May 2023

Denise Chanterelle DuBois’s transformation into a woman wasn’t easy. Born as a boy into a working-class Polish American Milwaukee family, she faced daunting hurdles: a domineering father, a gritty 1960s neighborhood with no understanding of gender nonconformity, trouble in school, and a childhood so haunted by deprivation that neckbone soup was a staple. Terrified of revealing her inner self, DuBois lurched through alcoholism, drug dealing and addiction, car crashes, dangerous sex, and prison time. Dennis barreled from Wisconsin to California, Oregon, Canada, Costa Rica, New York, Bangkok, and Hawaii on a joyless ride. Defying all expectations, DuBois didn’t crash and burn. Embracing her identity as a woman, she remade herself. Writing with resolute honesty and humor, she confronts both her past and her present to tell an American story of self-discovery.
The Last Deployment: How a Gay, Hammer-Swinging Twentysomething Survived a Year in Iraq
Authors: Lemer Bronson
Published: May 2023

In 2003, after serving five and a half years as a carpenter in a North Dakota National Guard engineer unit, Bronson Lemer was ready to leave the military behind. But six months short of completing his commitment to the army, Lemer was deployed on a yearlong tour of duty to Iraq. Leaving college life behind in the Midwest, he yearns for a lost love and quietly dreams of a future as an openly gay man outside the military. He discovers that his father’s lifelong example of silent strength has taught him much about being a man, and these lessons help him survive in a war zone and to conceal his sexuality, as he is required to do by the U.S. military. The Last Deployment is a moving, provocative chronicle of one soldier’s struggle to reconcile military brotherhood with self-acceptance.
Taboo
Authors: Rickel Boyer
Published: May 2023

An impressionistic memoir offers images of a life in progress, including scenes from Boyer Rickel’s rural Tempe, Arizona, childhood in the 1950s; his relationship with a physically shrinking father; his eccentric teenage friendships; his growing awareness of his sexuality among young, Hispanic gays; and a trip through Italy with his lover. A personal book, but also wholly universal, Taboo investigates the way one breaks through taboos and becomes a self-realized adult.
Hydrodynamics and Pollutant Distribution in the Mahi Estuary
Authors: Panda Satyananda , Ockendon Hilary , Ockendon John , Please Colin
Published: May 2023

It has been observed that pollutants mainly cause pollution in the Narmada river and the estuary, which is driven there during high and low tides. The modelling presented here concentrates on phenomena affecting the distribution of pollutants in the Gulf of Khambhat and the Estuaries. The model used for the tidal water movement in the Gulf is the shallow water equations with turbulent friction. A simplified linearised version of these equations is used in two idealised geometries to explore why the tidal amplitude and velocity can increase so significantly up the Gulf, and both resonance effects and the rapid narrowing of the Gulf are identified as being contributors. The wave elevation and velocity are described by a coupled system of partial differential equations that are spatially discretized and solved using an ODE solver.
Notas especulativas sobre sofrimento psíquico e performance musical
Authors: Brandão Luigi , Barbeitas Flavio
Published: May 2023

Propondo uma análise do sofrimento psíquico que pode atingir os músicos em situação de performance, o texto avança algumas considerações com base na metapsicologia de Sigmund Freud e em uma percepção crítica da formação dos intérpretes musicais. Procura-se, num primeiro momento, examinar as exigências éticas e morais sobre o intérprete situando-as metapsicologicamente como superegóicas. Em seguida, investigam-se possíveis relações entre Supereu, pulsão de morte e sublimação na produção de práticas insalubres no estudo e preparação de performances. Consideram-se nesta reflexão as relações do Eu com suas instâncias ideais no que podem contribuir para o estímulo ou supressão da sublimação. Uma última seção consiste na análise de passagens do romance O náufrago, de Thomas Bernhard, em que estas são cotejadas com as hipóteses anteriormente apresentadas.
Shotgun sequencing of sonication fluid for the diagnosis of orthopaedic implant-associated infections with Cutibacterium acnes as suspected causative agent
Authors: Ponraj Diana Salomi , Lund Michael , Lange Jeppe , Poehlein Anja , Himmelbach Axel , Falstie-Jensen Thomas , Jørgensen Nis Pedersen , Ravn Christen , Brüggemann Holger
Published: May 2023

Orthopaedic implant-associated infections (OIAIs) due to Cutibacterium acnes can be difficult to diagnose. The aim of this pilot study was to determine if metagenomic next-generation sequencing (mNGS) can provide additional information to improve the diagnosis of C. acnes OIAIs. mNGS was performed on sonication fluid (SF) specimens derived from 24 implants. These were divided into three groups, based on culture results: group I, culture-negative (n = 4); group II, culture-positive for C. acnes (n = 10); and group III, culture-positive for other bacteria (n = 10). In group I, sequence reads from C. acnes were detected in only one SF sample, originating from a suspected case of OIAIs, which was SF and tissue culture-negative. In group II, C. acnes sequences were detected in 7/10 samples. In group III, C. acnes sequence reads were found in 5/10 samples, in addition to sequence reads that matched the bacterial species identified by culture. These samples could represent polymicrobial infections that were missed by culture. Taken together, mNGS was able to detect C. acnes DNA in more samples compared to culture and could be used to identify cases of suspected C. acnes OIAIs, in particular regarding possible polymicrobial infections, where the growth of C. acnes might be compromised due to a fast-growing bacterial species. However, since SF specimens are usually low-biomass samples, mNGS is prone to DNA contamination, possibly introduced during DNA extraction or sequencing procedures. Thus, it is advisable to set a sequence read count threshold, taking into account project- and NGS-specific criteria.
Recent advances in the application of ionic liquids in antimicrobial material for air disinfection and sterilization
Authors: Song Xizi , Tian Rujin , Liu Kai
Published: May 2023

Airborne transmission is one of the most unpredictable routes of infection. Nowadays, airborne diseases increase ever than before because of the complex living air environment. Apart from the inorganic particles, active microorganisms including bacteria, viruses, and fungi are incorporated in the pathogens acting as threaten to public health, which can hardly be treated by the traditional air purification methods based on adsorption. Therefore, effective filtration material with antimicrobial activity is demanded to solve the problem. Ionic liquids (ILs) are a category of salts that remain liquid at room temperature. The stable physico-chemical properties and extremely low vapor pressure make them suitable for a wide range of applications. Thanks to the numerous combinations of cations and anions, as well as the ability of inheriting properties from the parent ions, Ils are believed to be a promising industrial material. In recent decades, several Ils, such as imidazolium, pyridinium, pyrrolidinium, phosphonium, and choline, have been found to have antimicrobial activity in their monomeric or polymeric forms. This work focuses on the antimicrobial activity and safety of the latest types of ionic liquids, discussing the synthesis or manufacturing methods of Ils for air purification and filtration. Furthermore, possible applications of Ils antimicrobial materials in medical instruments and indoor environments are mentioned to encourage the scientific community to further explore the potential applications of Ils.
Case report: Coronary allograft vasculopathy: an accurate reflection of the histopathological findings on cardiovascular magnetic resonance imaging
Authors: Napolitano Carmela , Grutter Giorgia , Francalanci Paola , Amodeo Antonio , Secinaro Aurelio
Published: May 2023

Heart transplant recipients undergo extensive invasive and non-invasive postoperative screening to exclude complications, such as allograft rejection and vasculopathy. Cardiac magnetic resonance imaging is a non-invasive, non-irradiating, diagnostic tool for monitoring graft health and identifying possible tissue rejection or myocardial fibrosis. We describe the case of a 29-year-old female heart transplant recipient admitted to our care center with a worsening clinical condition. The patient underwent clinical evaluation, blood tests, including troponin I and N-terminal pro brain type natriuretic peptide, transthoracic echocardiography, invasive coronary angiography, and cardiovascular magnetic resonance imaging. Cardiovascular magnetic resonance imaging showed widespread sub-epicardial hyperintensity of the myocardial segments along the course of the coronary arteries. T2 mapping sequences showed an elevated value and the myocardial native T1 values and extracellular volume percentage were significantly increased. Late gadolinium enhancement demonstrated a diffuse sub-epicardial hypersignal along the lateral, free, and left ventricular walls. All the sequences evidenced widespread hyper-enhancement of epicardial fat along the course of the thickened main coronary artery walls. One month later, the recipient underwent re-transplantation due to progressive worsening of the clinical condition and refractoriness to intravenous medication. The anatomopathological findings of the explanted heart provided impressive visualization of structural and histopathological changes. These results could guide the tailoring of preventive therapeutic strategies and non-invasive monitoring of cardiac grafts.
A novel model for predicting a composite outcome of major complications after valve surgery
Authors: Cheng Zhenzhen , Wang Yishun , Liu Jing , Ming Yue , Yao Yuanyuan , Wu Zhong , Guo Yingqiang , Du Lei , Yan Min
Published: May 2023

Background

On-pump valve surgeries are associated with high morbidity and mortality. The present study aimed to reliably predict a composite outcome of postoperative complications using a minimum of easily accessible clinical parameters.

Methods

A total of 7,441 patients who underwent valve surgery were retrospectively analyzed. Data for 6,220 patients at West China Hospital of Sichuan University were used to develop a predictive model, which was validated using data from 1,221 patients at the Second Affiliated Hospital of Zhejiang University School of Medicine. The primary outcome was a composite of major complications: all-cause death in hospital, stroke, myocardial infarction, and severe acute kidney injury. The predictive model was constructed using the least absolute shrinkage and selection operator as well as multivariable logistic regression. The model was assessed in terms of the areas under receiver operating characteristic curves, calibration, and decision curve analysis.

Results

The primary outcome occurred in 129 patients (2.1%) in the development cohort and 71 (5.8%) in the validation cohort. Six variables were retained in the predictive model: New York Heart Association class, diabetes, glucose, blood urea nitrogen, operation time, and red blood cell transfusion during surgery. The C-statistics were 0.735 (95% CI, 0.686–0.784) in the development cohort and 0.761 (95% CI, 0.694–0.828) in the validation cohort. For both cohorts, calibration plots showed good agreement between predicted and actual observations, and ecision curve analysis showed clinical usefulness. In contrast, the well-established SinoSCORE did not accurately predict the primary outcome in either cohort.

Conclusions

This predictive nomogram based on six easily accessible variables may serve as an “early warning” system to identify patients at high risk of major complications after valve surgery.

Clinical Trial Registration

[www.ClinicalTrials.gov], identifier [NCT04476134].
A plasma proteomic approach in patients with heart failure after acute myocardial infarction: insights into the pathogenesis and progression of the disease
Authors: Liu Yan , Huang Da , Li Zhile , Zhou LiuFang , Cen Tuan , Wei Baomin , Wei Liuqing , Wu Hongying , Su Liye , Sooranna Suren R. , Pan Xinshou , Huang ZhaoHe
Published: May 2023

Aims

The pathogenesis of disease progression targets for patients with heart failure after acute myocardial infarction was investigated by using plasma proteomics.

Methods

The plasma proteomes of acute myocardial infarction patients with (MI-HF) and without (MI-WHF) heart failure were compared. Each group consisted of 10 patients who were matched for age and sex. The peptides were analyzed by 2-dimensional liquid chromatography coupled to tandem mass spectrometry in a high definition mode. Parallel reaction monitoring (PRM) verified the selected target proteins.

Results

We identified and quantified 2,589 and 2,222 proteins, respectively, and found 117 differentially expressed proteins (DEPs) (≥1.5-fold), when the MI-HF and MI-WHF groups were compared. Of these 51 and 66 were significantly up-regulated and down-regulated, respectively. The significant DEPs was subjected to protein–protein interaction network analysis which revealed a central role of the NF-κB signaling pathway in the MI-HF patients. PRM verified that MB, DIAPH1, VNN1, GOT2, SLC4A1, CRP, CKM, SOD3, F7, DLD, PGAM2, GOT1, UBA7 and HYOU1 were 14 proteins which were highly expressed in MI-HF patients.

Conclusions

These findings showed a group of proteins related to the NF-κB signaling pathway in the pathogenesis of patients with poor outcomes after experiencing MI-HF. These proteins may be useful candidate markers for the diagnosis of MI-HF as well as help to elucidate the pathophysiology of this major cause of mortality in older patients.
Impact of pacing mode and different echocardiographic parameters on cardiac output (PADIAC)
Authors: Blessberger Hermann , Kammler Juergen , Kellermair Joerg , Kiblboeck Daniel , Nahler Alexander , Hrncic Denis , Saleh Karim , Schwarz Stefan , Reiter Christian , Fellner Alexander , Eppacher Christian , Sheldon Todd J. , Steinwender Clemens
Published: May 2023

Introduction

The extent of the hemodynamic benefit from AV-synchronous pacing in patients with sinus rhythm and AV block is not completely understood. Thus, we systematically investigated the association of an array of echocardiographic and epidemiological parameters with the change in cardiac output depending on the stimulation mode (AV-synchronous or AV-asynchronous pacing).

Methods

Patients in sinus rhythm after previous dual chamber pacemaker implantation underwent a thorough basic echocardiographic assessment of diastolic and systolic left ventricular function, and atrial function (26 echo parameters, including novel speckle tracking strain measurements). Then, stroke volume was measured with AV-synchronous (DDD) and AV-asynchronous (VVI) pacing. Each patient represented their own control, and the sequence of stroke volume measurements was randomized.

Results

In this prospective single-center study (NCT04068233, registration August 22nd 2019), we recruited 40 individuals. The stroke volume was higher in all patients when applying AV-synchronous DDD pacing [median increase 12.8 ml (16.9%), P < 0.001]. No echo parameter under investigation was associated with the extent of stroke volume increase in a linear regression model. Of all epidemiological variables, a history of acute myocardial infarction (AMI) was associated with an attenuated stroke volume gain in a univariate and a multivariate regression model that adjusted for confounders. A- and S-wave velocities were reduced in the AMI group.

Discussion

In our cohort of patients, each subject benefited from AV-synchronous DDD pacing. No single echo parameter could predict the amount of stroke volume increase. The beneficial effect of AV-synchronous pacing on stroke volume was attenuated after prior acute myocardial infarction.

ClinicalTrials.gov identifier (NCT number): NCT04068233.
Theoretical and methodological approaches to identifying deep accumulations of oil and gas in oil and gas basins of the Russian Federation
Authors: Prischepa O. M. , Kireev S. B. , Nefedov Yu. V. , Martynov A. V. , Lutsky D. S. , Krykova T. N. , Sinitsa N. , Xu Ruiming
Published: May 2023

A large number of oil and gas accumulations at deep and ultra-deep depths, recently revealed in the world due to the development of drilling technologies, forces a revision of theoretical ideas on many issues, including conditions of oil and gas formation and hydrocarbon conservation in zones of high pressures and temperatures, as well as evaluating the possibility of conservation and formation of reservoirs. Among the most discussed, in this regard, are the issues determining the processes and rate of oil and gas formation at deep and ultra-deep depths, which differ significantly from those at small and medium depths: Thermobaric conditions responsible for the possibility of formation, phase distribution and conservation of hydrocarbons, geochemical indicators—type of kerogen, and its transformation, responsible for the phase distribution and staging of generation peaks—lithological composition of kerogen-bearing strata—the rate and scale of dip and uplift and the timing of exposure to high temperatures—the formation of overlapping saline strata and the presence of deep conductive faults that significantly affect temperature and pressure gradients. Analysis of the influence of the above factors on the prospects of deep-lying complexes taking into account new studies and achievements, mainly in the sedimentary basins of China (Tarim, Jungar, Ordos, Sichuan), the Gulf of Mexico and offshore Brazil (Santos) allowed typifying the sedimentary basins and major depressions of Russia, with the allocation of areas with high and ultra-low depth potential for hydrocarbon studies. Thermobaric and historical and geological criteria have been developed and a methodology for detailed study of promising areas has been proposed, including a complex of geochemical studies of hydrocarbons, extracts of bitumoids (pyrolytic, chromatographic) and lithological and petrophysical core studies aimed at assessing the prospects of oil and gas content of deep complexes in Russian sedimentary basins and the subsequent localization of the most promising areas for deep drilling.
An exploration of reciprocity among teacher and students in female pre-professional ballet education: a shared reality theory perspective
Authors: Haraldsen Heidi M. , Solstad Bård E. , Fredriksen Danielle C. S. , Gustafsson Henrik , Nordin-Bates Sanna M. , Knight Camilla J.
Published: May 2023

The purpose of the present study was to explore perceptions of shared reality in teacher-student partnerships in ballet, and how these perceptions were related to experiences of quality in the relationship and well-being. A longitudinal qualitative study design was adopted, with three female ballet students and their teacher participating in three semi-structured interviews each over an eight-month period. Data were analyzed using a combination of thematic and narrative analysis. Findings indicated that across the teacher-student relationships there were perceptions of a shared reality only on the professional and distanced level and not on a relational and personal level. This was achieved by a common experience of what matters in the world of ballet education as well as students finding their teacher as trustworthy. Furthermore, it appeared that the authoritarian apprenticeship culture in ballet, where the teachers give clear instructions and feedback, and where the student role is to listen and adapt to the teacher’s instructions, was a barrier to fully achieving a shared reality on a personal and deeper level. In turn, this influenced the quality of the relationship and the wellbeing of both teacher and students. The present study offers critical reflections on the cultural backdrop of teaching and learning in ballet and highlights the importance of teachers to facilitate a supportive, unconditional, and trustworthy relationship so that they can work together in a more productive manner.
Disrupting cisheteronormativity in STEM through humanism
Authors: Jones Meg C. , Forsythe Desiree , Friedensen Rachel , Vaccaro Annemarie , Miller Ryan A. , Kimball Ezekiel , Forester Rachael
Published: May 2023

Cisheteronormativity is prevalent throughout college STEM discourses and classrooms. In this paper, we present findings from a U.S. based study focused on the experiences of collegiate STEM students with minoritized identities of sexuality and gender (MIoSG) as the backdrop for discussing how current harmful ideologies in STEM perpetuate cisheteronormativity through discursive practice. We propose that humanistic classrooms and pedagogy can work to dismantle cisheteronormative D/discourses in STEM and create MIoSG inclusive STEM classrooms and programs. Our findings highlight the ways participants experienced cisheteronormative D/discourses in their collegiate STEM contexts. We discuss how these experiences might be mitigated through humanistic educational approaches in college STEM contexts. Our aim is for readers to gain simultaneous theoretical and pragmatic insights on how cisheteronormative D/discourses operate in collegiate STEM classrooms and educational programs.