bluuebunny/crossref_metadata_2025 huggingface dataset:
O conflito “LTDA.COM(R)” nos julgados no STJ:
Authors: Lora Iago Farias , Ribeiro Gustavo
Published: January 2023

A aplicação de ferramentas computacionais à pesquisa jurídica muito pode enriquecer o estudo e a prática do Direito. Neste artigo, propõe-se evidenciar como a abordagem denominada Knowledge Discovery in Databases (KDD), de Fayyad, Piatetsky-Shapiro e Smyth (1996), pode ser utilizada para se identificar diversos elementos relacionados a uma questão jurídica. O tema tratado são os potenciais conflitos entre nomes empresariais, marcas e domínios virtuais, institutos que compõe os elementos intangíveis de identidade comercial e que, com o avanço da internet tenderiam a colidir, como hipótese inicial do trabalho. Ao se aplicar o método, busca-se explorar indicadores do caso (quantidade de casos, princípios citados, predominância de relatoria etc.), assim como apontar como a jurisprudência responde a esse eventual conflito. A coleta de casos se concentrou nos Recursos Especiais julgados no Superior Tribunal de Justiça, entre 2001 e julho de 2021. Os resultados indicam, entre outros, que o número de casos que efetivamente versam sobre a matéria não são tantos quanto se supunha imaginar; grande parte das discussões se concentram na Lei de Propriedade Industrial; dois ministros concentram quase 50% da relatoria dos casos e houve a predominância dos proprietários de nomes de domínio, nomes empresariais e marcas, nessa ordem, como parte vencedora.
NU AND NATIONALISM: A Study of KH. Achmad Shiddiq's Trilogy of Ukhuwah as an Effort to Nurture Nationalism Spirit of Indonesian Muslims
Authors: Ali Mursyid Azisi Ali Mursyid Azisi , Agoes Moh. Moefad
Published: January 2023

ABSTRACT

This article examines how the principles of Nahdlatul Ulama are related to the spirit of nationalism by analyzing the concept of the ukhuwah trilogy that was initiated by KH. Ahmad Siddiq, Jember. The ukhuwah trilogy consists of ukhuwah islamiyyah (to establish brotherhood with fellow Muslims), ukhuwah wathaniyyah (to establish brotherhood with fellow citizens), and ukhuwah basyariyyah (to establish brotherhood on the basis of fellow humans). The research method used in this research was qualitative descriptive analysis by utilizing primary and secondary literature sources. The analytical knife in this article borrowed Alvin L. Bertrand’s role theory, where the role of Kiai Achmad Shiddiq was so great in instilling brotherhood, nationalism or the spirit of nationalism in Indonesia without discriminating against culture, ethnicity, race, language, and even religion. The results of this study shows that the trilogy concept of ukhuwah is in accordance with Islamic principles, but is also important to be presented to the public in order to improve the quality of harmonious religion while instilling nationalism towards Indonesian Muslims. The prime goal is the common good. The benefit of this research is that it serves as an additional sub-material for academia (lecturers, students), religious leaders, and even the general public to further explore the excellent thoughts of an NU figure named KH. Ahmad Siddiq.

 

ABSTRAK

Artikel ini mengkaji tentang bagaimana prinsip Nahdlatul Ulama terkait semangat nasionalisme dengan menganalisis konsep trilogi ukhuwah yang dicetuskan oleh KH. Achmad Shiddiq, Jember. Trilogi ukhuwah terdiri dari ukhuwah islamiyyah (menjalin persaudaraan dengan sesama pemeluk Islam), ukhuwah wathaniyyah (menjalin persaudaraan dengan sesama anak bangsa), serta ukhuwah basyariyyah (menjalin persaudaraan atas dasar sesama manusia). Metode yang digunakan dalam penelitian ini adalah kualitatif analisis deskriptif dengan memanfaatkan sumber literatur primer dan sekunder. Pisau analisis dalam artikel ini meminjam teori peran Alvin L. Bertrand, di mana peran Kiai Achmad Shiddiq begitu besar dalam menanamkan sikap persaudaraan, nasionalisme atau spirit kebangsaan di Indonesia tanpa membeda-bedakan budaya, suku, ras, bahasa, bahkan agama. Hasil penelitian ini yaitu konsep trilogi ukhuwah selain sesuai dengan prinsip Islam, namun juga penting untuk dimunculkan ke muka publik dalam rangka meningkatkan kualitas beragama yang harmonis sekaligus menanamkan sikap nasionalisme terhadap muslim Indonesia. Tujuan besarnya bermuara pada kemaslahatan bersama. Manfaat penelitian ini adalah sebagai tambahan sub materi bahan ajar dan belajar bagi para akademisi (dosen, mahasiswa), agamawan, bahkan masyarakat umum, untuk lebih lanjut menggali pemikiran KH. Achmad Shiddiq.
Java Culture In The Qur'an Perspective (Case Study: Nyadran Culture In The Region Mt. Merapi Yogyakarta)
Authors: Nurrahma Nofa , Rifa’i Ahmad , Susilawati Susilawati
Published: January 2023

Cultural diversity and the plurality of Indonesian society is one of the wealth of the archipelago which is a distinct characteristic of other nations. The uniqueness of Javanese culture is an interesting study to examine. Nyadran culture is one of the customs that has become a tradition in the community around Mount Merapi, Yogyakarta, namely the event of cleaning graves and sending prayers to relatives and ancestors who have died. In the Pakem area of Dusun Kledokkan Yogyakarta, the Nyadran tradition still holds a meal together in the area around the cemetery and is attended by both Muslims and non-Muslims. This research is a phenomenological research with a qualitative approach, with a literature review and field observations through interviews with local community leaders, to then be presented in a descriptive analysis. The results of this study are Nyadran is the result of acculturation of Javanese culture which is influenced by Hindu teachings and has been Islamized. This shows a gradual change in the Nyadran process, such as a party or funeral meal that has been allocated in the area outside the tomb or pavilion. There was even something held at the house of Mr. Kadus to strengthen the friendship between the family members who were buried in the tomb. In the perspective of the Qur'an, this Nyadran activity can be likened to a pilgrimage to the grave which is one of the sunnahs to remind oneself of death that is sure to come.
Alfredo Seelinger
Authors: Seelinger Heloisa
Published: January 2023

O artigo busca reconstituir a trajetória de Alfredo Seelinger (1844-1876), traçando seu perfil biográfico e mapeando suas atividades como aluno da Academia Imperial de Belas Artes, caricaturista da revista ilustrada Bazar Volante, tenor da Capela Imperial e pintor de história. O artista, apesar de constar nos prestigiosos Allgemeines Künstlerlexicon, Bryan’s Dictionary e Benezit Dictionary, ainda é insuficientemente conhecido no Brasil.
The extent to which the requirements of international accounting education standards are applied in the accounting education curricula in Sudanese universities and their role in raising the efficiency of accounting graduates - case study Kassala universit
Authors: الفكي د. الفاتح الأمين عبد الرحيم , الحسن أ. محجوب الطيب محمد
Published: January 2023

The study dealt with the extent to which the requirements of international accounting education standards are applied in the accounting education curricula in Sudanese universities and their role in raising the efficiency of graduates - a case study of Kassala University. The problem of the study was the phenomenon of low efficiency of graduates of accounting departments from Sudanese universities, and this was expressed by a main question represented in the extent to which the requirements of international accounting education standards are applied in the accounting curricula in Sudanese universities. The study aimed to clarify the requirements of international accounting education standards when designing accounting curricula in universities, and to indicate the outputs of accounting education targeted from accounting programs and their role in raising the efficiency of graduates, in addition to studying and analyzing the requirements of international accounting education standards and comparing them with the accounting curricula in Sudanese universities. To achieve the objectives of the study, the researchers relied on the inductive approach, the deductive approach, as well as the comparative approach by addressing the requirements of international accounting education standards and comparing them with the curricula applied in Sudanese universities. The researchers reached many results, the most important of which are: The approach applied in the Department of Accounting and Finance, Kassala University does not take into account the requirements of international accounting education standards issued by the Accounting Education Standards Board (IAESB) and of the International Federation of Accountants (IFAC), the approach applied in the Department of Accounting and Finance, Kassala University does not contribute To provide the graduate with the necessary professional competence. The researchers also concluded a number of recommendations, the most important of which are: taking into account that the curriculum focuses on general issues in accounting education, the business environment and technical knowledge, that the assessment process for competencies should be graded according to levels, by addressing the complex issues that graduates may face in practice, and this is using Questions and applications that do not have definite answers.
Researchers’ Attitudes Towards Higher Education Issues in the Republic of Yemen
Authors: الخطيب د. خليل محمد
Published: January 2023

The study aimed to analyzing researchers’ attitudes towards higher education issues in Yemen. The study followed the descriptive approach. Data analysis was done by quantitative analysis and by qualitative analysis. The study reached a number of results, the most significant of which are the following: The number of the theses and dissertations related to higher education is (759), distributed as (67%) males and (33%) females, and as (72%) M.A. theses and (28%) Ph.D. dissertations. In addition, scientific productivity reached the highest level in 2014. Arabic language came first scoring (90%). Yemen as the country of such studies came first with a percent of (80%). Sana’a University came first with a percent of (42%). Moreover, researchers’ attitudes were distributed into (25) fields. Fields of “authority, leadership, administration, governance”, “quality and academic accreditation”, and ‘education technology came in the first three ranks respectively, with a percent of (53%) for such fields. The other fields scored (47%). In light of the results, the study offered some related recommendations and suggestions.
Narrativas de professores alfabetizadores sobre a formação e prática docente
Authors: Oliveira Genira Fonseca de , Fialho Lia Machado Fiuza , Falcão Giovana Maria Belém
Published: January 2023

As nuances vivenciadas na formação inicial e continuada dos professores reverberam na prática pedagógica e na identidade profissional. Este estudo tem por objetivo compreender a formação docente inicial e aquela desenvolvida por intermédio do Programa Alfabetização na Idade Certa, a partir dos significados produzidos por professores alfabetizadores que atuam no 2º ano do ensino fundamental. Com esteio nos pressupostos da Psicologia Histórico-Cultural, a investigação, de natureza qualitativa, tem suporte no método (auto)biográfico e possui como objeto de estudo as narrativas de dois docentes coletadas por meio de entrevistas narrativas. Os resultados evidenciaram: que a escolha profissional foi influenciada pelas relações familiares; que a trajetória formativa inicial foi aligeirada e precária, não capacitando para o exercício docente na escola; e que a formação no referido Programa levava os professores a acreditarem que orientações padronizadas e prescritivas eram regra de conduta, significando-as como positivas, ainda que pouco considerassem o contexto sócio-histórico. Conclui-se que há a necessidade de investir em formação continuada crítica, ressignificando os processos formativos pragmáticos, de modo que favoreçam a autonomia e a reflexão, com os professores no centro das discussões, a partir de suas realidades diversas.
O exercício da docência para ensinar matemática: o “mesmo do mesmo” e o “imperativo da falta”
Authors: Boff Daiane Scopel , Pozzobon Marta Cristina Cezar , Oliveira Cláudio José de
Published: January 2023

Este artigo trata da(s) docência(s) de professores que ensinam Matemática nos anos finais do Ensino Fundamental. A reflexão apresentada emerge de uma pesquisa que investigou: o que dizem os professores que ensinam Matemática em tempos de pandemia sobre a docência nos anos finais do Ensino Fundamental? e de que forma esses ditos provocam outros modos de pensar a docência? O material de pesquisa foi gerado por meio de questionário on-line pensado para entender o exercício docente em tempos pandêmicos e não pandêmicos. A analítica empreendida mostra que as docências em tempos de pandemia, sobretudo no ensino remoto, tendem a reproduzir o mesmo modo ritualizado do ensino presencial e a potencializar o que nomeamos de “imperativo da falta”: falta de interesse, de participação, de compreensão da linguagem matemática, de acesso à Internet. A partir disso, destaca-se a importância do tempo para o exercício do pensamento e para a produção de experiências que toquem e transformem a vida, de modo que o ser-fazer da docência seja compreendido também como uma potência humanizadora.
Pedagogia do erotismo no currículo bareback: a transgressão às normas do uso do preservativo nos vídeos pornôs
Authors: Oliveira Danilo Araújo de , Sales Shirlei Rezende
Published: January 2023

Considerando a dimensão educacional dos filmes pornôs, descrevemos e analisamos, neste texto, a pedagogia do erotismo na perspectiva pós-crítica curricular. Compreendemos que currículo não se restringe às disciplinas escolares, mas se constitui em diferentes espaços e artefatos culturais. A metodologia utilizada na investigação que subsidia este artigo articulou elementos da netnografia e análise do discurso de inspiração foucaultiana. Na produção de informações, nomeamos um conjunto heterogêneo de ditos, vídeos e imagens publicados no ciberespaço de currículo bareback. Nosso foco de análise aqui é um conjunto de vídeos pornôs. O argumento desenvolvido é o de que os vídeos pornôs divulgados nesse currículo têm uma função de divulgar o bareback como uma prática transgressiva dos valores socialmente sancionados sobre o uso do preservativo nas relações sexuais entre homens. Incita-se a violação à norma do uso compulsório da camisinha, contribuindo, assim, para tornar a prática bareback objeto de desejo, por meio do estímulo de fantasias eróticas específicas.
Gênero, educação e moda: perambulações curriculares em um museu
Authors: Alves Cláudio Eduardo Resende
Published: January 2023

Este artigo é um recorte da investigação de Pós-Doutorado em Educação realizada na Universidade Federal de Minas Gerais (UFMG) entre os anos de 2020 e 2021, que teve como foco problematizar as relações de gênero ditas, não ditas e interditas no acervo de diferentes museus da cidade de Belo Horizonte, MG. À luz dos estudos pós-críticos de gênero e currículo, foram realizados encontros, observações e interlocuções imaginativas com discentes e docentes de escolas públicas, bem como com as equipes do setor educativo de cada espaço, durante as visitas aos museus. Nessa fricção, foi concebida a ideia de currículo-museu, isto é, um artefato cultural que ensina e produz leituras sobre o mundo, podendo acontecer em territórios outros, como o museu. Para a construção do texto, foi escolhido o Museu da Moda e selecionados três (des)objetos museais, compreendidos como um exercício discursivo de estranhamento de gênero no museu – uma antiga máquina de costura, uma bolsa de veludo e um chapéu de palha  – como elementos problematizadores na pesquisa teórica e empírica. Os resultados evidenciam que um currículo-museu oportuniza potentes composições com (des)objetos em museus, gerando deslocamentos na prática do aprender sobre gênero. Por fim, o estudo sinaliza a relevância de uma prática curricular ampliada pautada no debate das relações de gênero e da diversidade no museu.
Pedagogia do afeto: articulações entre docência, gênero e sexualidade no cinema
Authors: Cruz Éderson da , Dal'Igna Maria Claudia
Published: January 2023

Este artigo retoma os principais resultados de uma pesquisa de Doutorado realizada no Sul do Brasil, que investiga de que modos gênero, em articulação com a sexualidade, constitui a docência no âmbito do filme Entre os muros da escola, filme francês, dirigido por Laurent Cantet (2008). A pesquisa dialoga com os campos dos Estudos de Gênero numa perspectiva pós-estruturalista, dos Estudos Queer, dos Estudos sobre Docência, dos Estudos sobre Cinema e dos Estudos Culturais. Por meio do procedimento metodológico de etnografia de tela, busca-se descrever e analisar o filme, a partir de uma perspectiva de que esse é um artefato cultural pedagógico, mas que se propõe a representar, de modo central, a escola, o currículo escolar e a docência em seu cotidiano. Os resultados aqui apresentados estão sustentados também por um projeto de pesquisa mais amplo, intitulado “A produção de sentidos sobre afeto, amor e cuidado na formação inicial docente sob a perspectiva de gênero”. Para este artigo, destaca-se que, a partir da análise do artefato cultural pedagógico em questão, pode-se sustentar a tese de que gênero, articulado à sexualidade, constitui um modo de ser docente que, ao ser colocado em exercício, opera constituindo o que se pode chamar de uma “pedagogia do afeto”.
Literacia familiar e o governo de mulheres-mães: o currículo do Conta pra Mim e a conformação de corpos-femininos no espaço doméstico
Authors: Vasconcelos Maria Beatriz de Freitas , Caldeira Maria Carolina da Silva
Published: January 2023

Este artigo apresenta um recorte de uma pesquisa em que se analisou um documento disponibilizado pela Política Nacional de Alfabetização no Brasil (PNA), o Guia de Literacia Familiar. Este artefato cultural é parte central do programa do Governo Federal Conta pra Mim, que foi lançado em 2019, com o objetivo de incentivar um modo de praticar a leitura, a escrita e estímulos ao desenvolvimento da oralidade, com as crianças e suas famílias, em casa. Embora tenha objetivos que se vinculam ao currículo escolar, o Guia se direciona para as famílias, constituindo-se, portanto, como um currículo não escolar, que convoca as famílias a assumirem determinadas posturas que comumente são esperadas da escola. O objetivo deste trabalho é mostrar, com base nos estudos pós-críticos de currículo, como o Guia de Literacia Familiar atua como currículo cultural e recorre a técnicas de biopoder para operar conformando corpos-femininos no espaço doméstico de diferentes formas. Argumenta-se que este currículo, implementado para ser efetivado na esfera doméstica, que aciona evidências científicas com relação ao “hábito materno” para se legitimar, intenciona convocar as mulheres-mães para acatarem essa responsabilidade, uma vez que elas ainda são a maioria entre as pessoas que ocupam o espaço doméstico.
O currículo “imita” a arte: relações fronteiriças potencializadas na dança-teatro de Pina Bausch
Authors: Carvalho Ana Paula Pereira Marques de , Frangella Rita de Cássia Prazeres
Published: January 2023

O texto em tela parte do mote “O Currículo ‘imita’ a Arte”, visando suscitar reflexões sobre o campo curricular como um movimento fluido que não se encerra nos muros da escola. Trazemos ao debate experiências de experimentações artísticas e a dança-teatro de Pina Bausch, as quais mobilizam debates que extrapolam lógicas binárias, incidindo sobre a concepção de significação como processo fluido, híbrido. Nas fronteiras entre a tradição do ballet e as próprias performances dessa tradição, os palcos de Pina trazem a dança como experiência, algo ambivalente, em que o novo sempre eclode, rompendo essa tradição, em função dos processos de enunciação cultural. Nesse percurso, trazemos Homi Bhabha e Jacques Derrida, os quais, em diálogo com a dança-teatro de Pina Bausch, permitem-nos adensar uma perspectiva discursiva pós-estrutural sobre currículo como movimento que se hibridiza na relação com o outro em que as tentativas de reprodução – imitação – são processos de diferimento. Assim, as apropriações que fazemos para o campo do currículo – e que trazemos neste texto – nos permitem problematizar os sentidos de currículo como um novo contaminado. Defendemos, portanto, a provisoriedade e a experiência sempre outra da produção curricular que é sempre fronteiriça, tal qual nos propõe a dança bauschiana.
Jogo-Formação do Eterno Retorno
Authors: Marques Vitor , Carvalho Maria Inez
Published: January 2023

Partindo de fabulações de uma outra de nós, com argumentos que deslizam, apoiados na teoria dos jogos, pelo pós-moderno, notadamente, o pós-estruturalismo e o pós-fundacional, escrevemos este artigo como autoficção. A personagem é Maria, uma outra de nós, que participa de um jogo-formação. Operando em condição performativa de quatro fases em branco, fabulou cenários escolares em um agenciamento de saberes e fazeres para mobilizar singulares contextos de práticas a partir de quatro cartas, a saber: Absurdo, de Camus; Niilismo, de Nietzsche; Literatura Menor, de Deleuze e Guattari; e Ontologia Fraca, de Vattimo. Ciente do eterno retorno do jogo, Maria transitou pelo experimentalismo como opção metodológica, considerando cada carta como um tema, quatro lentes que possibilitaram experimentos com o pensar, para reivindicar e fabular cenários escolares. Ela estava disposta a dar o seu melhor possível, até um dizer sim a cada carta, nas jogadas dilemáticas sobre o papel social da escola, sem atribuir uma única carta como argumento de certeza, mas enxergar a potência de cada uma delas e jogá-las de forma que desejasse jogar de novo.
Apresentação do dossiê: Currículos culturais não escolares: sobre um campo em constante expansão, invenção e criação para afirmação da vida
Authors: Oliveira Danilo Araújo de , Frangella Rita de Cássia Prazeres
Published: January 2023

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The Potency of Water Clover (Marsilea crenata C. Presl.) Leaves as Anticholesterolemic Functional Foods Through In Silico Study
Authors: Hardoko Hardoko , Syahrani Nurul Mutmainannah
Published: January 2023

Highlight Research
1. There were 26 active compounds from water clover leaf extract that were identified using GC-MS
2. In silico approach was used to screen potential anticholesterolemic compounds from water clover leaf extract
3. Anticholesterolemic compounds from water clover leaf extract were interacted with HMG-CoA reductase receptors and compared to native ligand and medicine
4. There were 6 potential anticholesterolemic compounds identified from water clover leaf extract
 
Abstract
 
Water clover (Marsilea crenata C. Presl.) is a widely available plant in Indonesia and often utilized as a traditional food ingredient. This plant is also traditionally believed to contain compounds that can decrease blood cholesterol. This study aimed to determine the compounds in water clover which have the potential to decrease blood cholesterol through inhibition of the HMG-CoA enzyme using in silico approach. This research was done in several steps, i.e., extraction using ethyl acetate solvent, identification of chemical compounds using GC-MS, and screening of compounds with potential to be  anticholesterolemic agent through in silico using PyRx 0.8 (AutoDockVina and  Open Babel GUI version 2.4.1), Discovery Studio Visualizer 2021, and PyMOL™ 1.7.4.5 software. Results showed that ethyl acetate extract of water clover contained 26 compounds, 6 of which were potential to be anticholesterolemic agent, i.e., phytol, 1,2-benzenedicarboxylic acid, 2,4-di- tert-butylphenol, diethyl phthalate, 1,2,3,4-tetramethylbenzene, and dipentene. Binding affinity values of those six compounds were lower than the native ligand of the HMG-CoA reductase, although still higher compared to pravastatin. The binding affinity value of pravastatin was -7.13 kcal/mol and the binding affinity value of 3-methyl glutaric acid as a native ligand was -5.33 kcal/mol, meanwhile, the lowest binding affinity value of compounds in water clover was phytol (-6.37 kcal/mol) and the highest was dipentene (-5.40 kcal/mol). Through in silico study, there were six compounds from water clover leaf’s ethyl acetate extract that could inhibit the HMG-CoA reductase. Therefore, water clover leaf has the potential to become an anticholesterolemic functional food ingredient.
Effect of Cooking Methods on Nutritional Quality of Sea Lettuce (Ulva lactuca) Flakes
Authors: Sefrienda Ardiba R. , Jasmadi Jasmadi , Novianty Hilda , Suryaningtyas Indyaswan T. , Wikandari Rachma
Published: January 2023

Highlight Research

Proximate of Ulva lactuca after cooking treatments were analyzed. The cooking treatments carried out in this study were roasted and boiled-roasted
Protein quality such as in-vitro digestibility, protein solubility, and amino acids composition of Ulva lactuca after cooking treatments were analyzed
The result showed that boiled-roasted samples had the highest protein content, amino acid score and essential acid index, and predicted-protein efficiency ratio

 
Abstract
Plant-based protein has been increasingly demanded as a sustainable protein source. Sea lettuce (Ulva lactuca) is one of the potential sources as plant protein due to its high protein content. During processing, the sea lettuce is exposed to heat which might affect its nutrition, particularly the protein quality. This study aimed to evaluate two different cooking processes on the nutritional quality of the sea lettuce based on the proximate and protein quality analyses. The samples were raw, roasted, and boiled-roasted sea lettuce. All treatment using temperature 100°C. The protein quality was assessed by in-vitro protein digestibility, solubility, and amino acid profiles. The result showed that boiling treatment followed by roasting treatment had significantly higher protein content, amino acid score and essential amino acid index, and predicted-protein efficiency ratio compared with the value of roasting treatment only. It resulted in protein content of 18.87% (dry basis), amino acid score of 37.96%, essential amino acid index of 79.41% and predicted-protein efficiency ratio of 2.58. Therefore, boiling followed with roasting process is recommended to maintain the nutrition quality of sea lettuce.
Immersion Effect of Estradiol-17β on Cannibalism of Asian Redtail Catfish (Hemibagrus nemurus) Post Larvae
Authors: Heltonika Benny , Sudrajat Agus Oman , Zairin Muhammad Junior , Widanarni Widanarni , Suprayudi Muhammad Agus , Manalu Wasmen , Hadiroseyani Yani
Published: January 2023

Highlight Research

The dose, duration of immersion, and time interval of immersion of the estradiol-17β affect the rate of cannibalism and increase the seed survival of Asian redtail catfish in low treatment in this research.
Over optimum treatment increased the incidence of cannibalism at Asian redtail catfish and decrease growth performance.
Treatment of estradiol-17β, give the ability of Asian redtail catfish to live on high density
The treatment of estradiol-17β, has an effect on concentration plasma of body testosterone and cortisol

 
Abstract
The cannibalistic behavior of Asian redtail catfish greatly hampers the supply of these fish seeds, invoking the need to be controlled. Estradiol is one of the hormones that has been known to reduce cannibalistic behavior on fish. This study aimed to evaluate the effect of estradiol-17β immersion on the incidence of cannibalism in the rearing of post larvae of Asian redtail catfish. Post larvae was treated with a combination of doses of estradiol hormone 0, 1, and 2 ppm and immersion time of two and four hours with immersion intervals of three and six days with a completely randomized design. Each treatment had a fish density of 10 fish L-1, with mean size individual length of 6.73 ± 0.73 mm (three days of age after hatched), with four replications. Fish were fed with tubifex up until satiation point and reared for 30 days. The results showed that the administration of the estradiol-17β through immersion with a dose of 1 ppm for two hours and interval of six days was able to reduce the level of cannibalism and increase the survivability. A further increase in dose, immersion time, and interval had the opposite effect. Estradiol-17β immersion with certain dose, duration, and interval affected the rate of cannibalism, growth rate, and survival. Estradiol-17β immersion at a dose of 1 ppm for two hours and six days interval was the best to reduce the level of cannibalism and normal mortality in post larvae of Asian redtail catfish.
Effect of Dosages and Temperatures on Simalungun Red Ginger (Zingiber officinale var. Rubrum) Ethanol Extract Dipping on Masculinization of Zebra Fish (Danio rerio) as a Model Fish
Authors: Febriani Eka Fitria , Widodo Maheno Sri , Faqih Abdul Rahem
Published: January 2023

Highlight Research

Successive administration of Ginger ethanol extract to male individuals was shown to be able to produce a significant increase in sperm count, motility, viability and morphology
Ethanol extract of ginger has androgenic activity which is proven to be able to increase the concentration of testosterone in serum, which functions to control the process of spermatogenesis, maintain Sertoli cells and play a role in determining the quality of spermatozoa in male organisms
Giving ginger ethanol extract for 30 consecutive days to male individuals showed significant results so that ginger extract was thought to have the potential to improve male characteristics
Ginger extract is potentially useful in improving healthy sperm characteristics and management of male infertility especially in those with low sperm counts

 
Abstract
Ornamental fish are known to be easily cultivated in aquarium or pond. Many people prefer male (MF) over female fish (FF) due to their aesthetic value and productivity which lead to better pricing. The aim of this study was to determine the effect of Simalungun Red Ginger (Zingiber officinale var. Rubrum) (SRG) on masculinization. This study used dipping method which was carried out using Simalungun Red Ginger (Zingiber officinale var. Rubrum) (SRG). The temperature treatments used in this study were 28°C and 32°C. For this research, an experimental study with a Completely Randomized Factorial Design (CRFD) method that had two independent variables such as different dosages and temperatures was used. From five dosages (0 mg/L; 5 mg/L; 10 mg/L; 15 mg/L; 20 mg/L) and three temperature treatments (ambient temperature (about 25°C; 28°C; 32°C), it was found that the highest male percentage of primary sexuality (88.33%), secondary sexuality (85%), and highest total testosterone levels (TL) (1.986 ng/L) were at the treatments with the highest dosages and temperature, while for the highest survival rate were at almost in all B treatments (5 mg/L) and b levels (28°C), in which the survival rate was 100%. For all of these results above, the results were significant.
Impact of Enzymatic Hydrolysis on Antioxidant Activity of Snakehead Fish (Channa striata) Head Protein Hydrolysate
Authors: Agustin Venny , Putra Masagus Muhammad Prima , Husni Amir
Published: January 2023

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Snakehead fish head possess high protein content and potential to be used as materials for protein hydrolysate
Snakehead fish head protein hydrolysis optimum condition were determined
Snakehead fish head hydrolysate protein antioxidant activity were analyzed
Snakehead fish head is potential to be used as materials for fish protein hydrolysate

 
Abstract
There is concern regarding the use of synthetic antioxidants which spurred the yearly increase of natural antioxidants to substitute synthetic ones. Fish protein hydrolysate (FPH), which has been reported to have potent antioxidant properties, could be utilized to solve this problem. This study aimed to utilize the by-product of snakehead fish (head) and determine the optimum hydrolysis conditions to obtain FPH with antioxidant activity. Two parameters were tested during the hydrolysis process: enzyme concentration (papain enzyme) and hydrolysis time. The optimum condition was evaluated by measuring dissolved protein, hydrolysis degree (DH), and antioxidant activity, including DPPH, ABTS, and FRAP. The optimal hydrolysis conditions were 5% enzyme concentration and 6 h of hydrolysis time at 55°C and pH 7.0. The DPPH, ABTS, and FRAP antioxidant activities were 50.70%, 66.67%, and 1.35 M Tr/mg, respectively. Based on the antioxidant activity, Snakehead fish head has the potential as a source of natural antioxidants.
Mollusk Diversity in Percut Sei Tuan Silvofishery Ponds, North Sumatra, Indonesia
Authors: Susetya Ipanna Enggar , Basyuni Mohammad , Rifzy Muhammad Rakezza Rifzy , Amelia Rizka , Bimantara Yuntha , Leidonald Rusdi , Fadhilah Amanatul
Published: January 2023

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We found 16 species of mollusks with a total of 15 species from the gastropod class and 1 species from the Bivalvia class bivalves in the silvofishery ponds, recording a total of 369 individuals.
The density of mollusks in July in pond I was 3.6 ind/m2, while it was 10.66 ind/m2 in pond II.
The mollusk diversity index in October after rehabilitation was included in the high diversity category because the value of H' was 1.6 - 3.0. Pond I has a diversity index value of 1.89 and pond II 1.82.
The value of C-organic concentration in both ponds ranged from 3.00% to 5.72%, which is the optimum level for mollusk growth.

 
Abstract
Silvofishery is a system that combines mangrove and fishery to protect mangrove ecosystems and restore their functions, one of which is as a habitat for macrozoobenthos. Investigate the mollusks and mangrove density. Mollusk sampling was carried out on sub-plots measuring 1 x 1 m² in the mangrove vegetation transect, and mangrove density was measured by counting the number of trees directly on all of the mangrove species at two silvofishery ponds. A total of 16 species of mollusks were found at the observation site, consisting of gastropods and bivalves. The density of mollusks in July was 20 ind/m2 in pond I, while it recorded 9 ind/m2 in pond II. In October, after pond II rehabilitation, the density was inversely proportional to July, and the highest density was found in pond I at 10 ind/m2, while pond II measured 9 ind/m2. After rehabilitation, the index value H’ decreased in pond I and pond II from 2.82 and 2.98 to 2.52 and 2.68, respectively. The mangrove density was 887 ind/ha in pond I and 686 ind/ha in pond II. The substrate in both ponds was clay. Nitrate concentration values ​​in the substrate in both ponds ranged from 0.27% to 0.29%, phosphate recorded a percentage of 0.07–0.09%, and C-organic ranged from 3.00% to 5.72%. The water's physicochemical parameters and the type and content of the substrate were still suitable for mollusk life.
Modified Media for Fungi Symbiont Sponge Agelas sp. (Fusarium sp.) Cultivation against Multidrug-Resistant Bacteria
Authors: Wittriansyah Khoeruddin , Trianto Agus , Radjasa Ocky Karna
Published: January 2023

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Fusarium symbiont Agelas sponge has antibacterial activity against aureus and E. coli Multi Drug Resistant
Fusarium can grow on modified media soursop juice (SJ) and ginger juice (GJ) and has different inhibitory abilities against bacteria test
Fusarium bioactive compounds were analyzed and purified by HPLC
Based on TLC visualization, one of the bioactive compounds contained in Fusarium is a steroid group

 
Abstract
Marine symbiont fungi, specifically, are likely to have antibacterial properties. The production of secondary metabolites in cultures is strongly influenced by nutrient availability. This study aimed to study the modified media for the cultivation of Fusarium sp. and its antibacterial bioactivity. Fusarium sp. was isolated from Agelas sp. sponge collected from Riung Sea, East South Nusa, Indonesia. In this study, the modified media was soursop juice (SJ), ginger juice (GJ), and sago (S). The fungal mycelium was cultured and scaled up for 7–14 days until the mycelium achieved maximum growth. A filtration funnel and HPLC were used to purify the bioactive compounds. The diffusion agar method was used to test antibacterial activity against the multi-drug resistant (MDR) Staphylococcus aureus and Escherichia coli. The results indicated that Fusarium sp. could grow on soursop juice and ginger juice but could not grow on sago media. The inhibition zone produced by the filtration fraction of Fusarium sp. from each media differed. The soursop juice media produced the largest inhibition zone against both S. aureus (11.56 mm ± 0.140) and E. coli (12.16 mm ± 0.094) at 100 μg/disc. The ginger juice (GJ) and soursop juice (SJ) media are promising as alternative culture media for Fusarium sp. The structure of the bioactive compound Fusarium sp. from GJ and MJ media culture can be further investigated using NMR.
Identification of a Potential SNP Related to the Expression of Immune Genes and Its Possible Application to Selection of WSSV-Resistant Pacific White Shrimp (Litopenaeus vannamei)
Authors: Basuki Bagus Rahmat , Alimuddin Alimuddin , Soelistyowati Dinar Tri , Nuryati Sri
Published: January 2023

Highlight Research

A molecular marker for shrimp selection in disease resistance.
Single nucleotide polymorphisms (SNP) in the ALF gene strongly correlate with shrimp resistance to WSSV infection.
Higher ALF gene expression in survivor shrimp.
SNP as molecular marker inherited in the first generation (G1) shrimp.
ARMS-PCR method successfully detect SNP in the shrimp ALF gene.

Abstract
The Pacific white shrimp (Litopenaeus vannamei) is Indonesia’s main export commodity, but its production is constrained by the white spot syndrome virus (WSSV). Selective breeding of disease-resistant broodstock based on single nucleotide polymorphism (SNP) in the anti-lipopolysaccharide factor (ALF) gene is an alternative strategy for solving the disease problem. This study aimed to detect the SNP g.455 A>G in the anti-lipopolysaccharide factor (ALF) shrimp gene, evaluate the correlation of SNP with WSSV-resistance trait, analyze the expression level of immunity genes and genotype frequencies of the WSSV-resistance population shrimp and analyze the SNP inheritance in the first generation of selected shrimp. A total of 120 individuals from 4 families were used to detect the SNP marker using tetra-primer amplification refractory mutation system-polymerase chain reaction (ARMS-PCR). The correlation of the SNP marker with survival rate (SR) was analyzed using a general linear model (GLM) between genotype frequencies and SR. Genotypic similarities between broodstock and pedigree were analyzed using Chi-square. SNP g.455 A>G was successfully detected using the ARMS-PCR method and had a strong correlation between the marker and SR (p-value of AA = 0.012; AG = 0.359, and GG = 0.001). The resistant population has significantly higher ALF and SOD gene expression levels and AA genotype frequency. The SNP marker was inherited, so the broodstock and pedigree have the same genotype frequencies according to chi-square analysis (χ2 = 0.46 and p-value = 0.497). These results suggested that the g.455 genotype AA could be selected to produce WSSV-resistant Pacific white shrimp.
Profile of Exon 20 T790M Mutation Incidence Rate with Plasma ctDNA in Lung Adenocarcinoma Patients Receiving EGFR-TKI Treatment
Authors: Praditya Muhammad Harbi , Soeroso Noni Novisari , Tarigan Setia Putra , Ashar Taufik , Lim Darren Wan-Teck
Published: January 2023

Introduction: Patients with lung adenocarcinoma following epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) treatment will develop acquired resistance after 7 to 16 months of starting the medication, indicated by the emergence of exon 20 T790M mutations. This study aimed to identify the clinical and demographical profile of acquired resistance in patients with lung adenocarcinoma receiving EGFR-TKI therapy through plasma circulating tumor deoxyribonucleic acid (ctDNA) examination.
Methods: This was a descriptive study with a retrospective cross-sectional design involving 108 lung adenocarcinoma patients who received EGFR-TKI for more than six months. Exon 20 T790M EGFR mutations were identified as a sign of acquired resistance using the digital droplet polymerase chain reaction (ddPCR) approach to examine plasma ctDNA Utilizing the Statistical Package for the Social Sciences, statistical tests were used to examine the data (SPSS). The data were analyzed by statistical tests using the Statistical Package for the Social Sciences (SPSS).
Results: A total of 31 patients were recruited as study participants. The majority of the research subjects were female (64.5%), aged 20-69 years old (58%), and non-smokers (67.7%). Exon 19 deletions were the most prevalent EGFR mutation (58.1%). The incidence of acquired resistance was found in 10 subjects (32.3%). Patients with acquired resistance were predominately female (70%), non-smokers (80%), and with gefitinib therapy (90%). The average time for EGFR-TKI treatment until acquired resistance occurred was 12.6 months.
Conclusion: The incidence of acquired resistance was mainly found in women without a smoking history after 12.6 months of treatment with EGFR-TKI.
Hematologic Paraneoplastic Syndrome in Newly Diagnosed Patients with Lung Cancer
Authors: Putra Andika Chandra , Jonathan Steven , Winardi Wira , Syahruddin Elisna
Published: January 2023

Introduction: Lung cancer could have signs and symptoms generated by paraneoplastic syndromes. This study aimed to describe and analyze hematologic paraneoplastic syndrome in patients with lung cancer in Indonesia.
Methods: This was a cross-sectional analytic study conducted in Persahabatan National Respiratory Referral Hospital, Jakarta, between September 2018 and February 2019, on all newly diagnosed patients with lung cancer whose diagnosis was established and who fulfilled the inclusion and exclusion criteria.
Results: The mean age of subjects was 56.7 ± 11.4 years old. Most subjects were male, had normal nutritional status (42.6%), had a smoking history (75%), and had a moderate Brinkman Index (BI) value (52%). The most common type of histology was squamous cell carcinoma (SCC) (39.7%), with advanced stage (83.8%) and performance status <2 (94.1%). Paraneoplastic anemia was 40.4%, associated with poor nutritional status and commonly normocytic normochromic anemia. The proportion of paraneoplastic leukocytosis was 39%, associated with males and smoking history. The proportion of paraneoplastic neutrophilia was 51.5%, and it was related to males, smoking history, and SCC histology type. Paraneoplastic hypereosinophilia and thrombocytosis proportions were 2.9% and 18.4%, respectively. The proportion of paraneoplastic hypercoagulability was 91.2%, which was caused by the elevated D-dimer level.
Conclusion: The most common hematologic paraneoplastic syndromes in patients with lung cancer were hypercoagulability, neutrophilia, and anemia. The low hemoglobin (Hb) level of paraneoplastic anemia was associated with low body mass index (BMI). Male and smoking history in lung cancer patients were associated with paraneoplastic leukocytosis and/or neutrophilia.
COVID-19 Severity based on Deep Convolutional Neural Networks Chest X-Ray Image in Aceh, Indonesia
Authors: Yanti Budi , Nurdin Yudha , Geumpana Teuku
Published: January 2023

Introduction: Every area of our lives has been devastated by the worldwide Coronavirus disease 2019 (COVID-19) epidemic. However, the development of artificial intelligence has made it possible to build advanced applications that can fulfill this level of clinical accuracy. This study aimed to create a deep learning model that can detect COVID-19 from a chest image dataset of confirmed patients treated at the provincial hospital in Aceh.
Methods: Eight hundred confirmed COVID-19 patients' chest X-ray photos were gathered locally from Dr. Zainoel Abidin General Hospital, Banda Aceh. Performance was evaluated in several ways. First, the dataset was used for training and testing. Second, the data was used to train and test the model. VGG16 is a robust network adapted to an enhanced dataset constructed from a confirmed COVID-19 chest X-ray pool. To artificially produce a huge number of chest X-ray pictures, this study used data augmentation techniques such as random rotation at an angle between 10 and 10°, random noise, and horizontal flips.
Results: The experimental results were encouraging: the proposed models classified chest X-ray pictures as normal or COVID-19 with an accuracy of 97.20% for Resnet50, 98.10% for InceptionV3, and 98.30% for VGG16. The results showed the outstanding performance of straightforward COVID-19 diagnosis with the classification of COVID-19 severity, such as mild, severe, and very severe.
Conclusion: These made it possible to automate the X-ray image interpretation process accurately and could also be applied when materials and reverse transcription polymerase chain reaction  (RT-PCR) tests are scarce.
Implementing Palliative and End-of-Life Care in Lung Cancer: When to Start?
Authors: Haryati Haryati , Rahmawaty Desi , Wanahari Tenri Ashari
Published: January 2023

Lung cancer is among the most prevalent cancers and the primary cause of cancer-related mortality. Despite advances in treatment, patients often have a poor prognosis, with a limited survival period, particularly in advanced stages. Significant morbidity is linked with lung cancer, and symptoms are frequently inadequately controlled, resulting in a considerable symptom burden for patients and their family caregivers. It is typically accompanied by an overall reduction in one’s quality of life (QoL). Palliative care is an established therapy paradigm that successfully enhances symptom management and physical and mental health. It can be initiated as soon as the patient develops symptoms (even in the early stage) or is diagnosed with a late stage. Over the past few decades, palliative care has become a vital part of comprehensive care for people, especially those with advanced diseases. Early palliative care (EPC) integration within the oncology setting is more effective than standard care in enhancing the patient’s QoL and length of survival, resulting in less intrusive end-of-life care. When caring for lung cancer patients, medical practitioners must remember their duty to cure occasionally, routinely alleviate, and constantly comfort the patient. Treating physical symptoms, illness comprehension, coping, and psychological and spiritual anguish are all vital components. Intervention strategies by multidisciplinary teams concentrating on the patient and their family and dealing with the circumstances are essential. All health providers should prioritize palliative and end-of-life care to enhance care and assist patients and their families in navigating the final period of life.