bluuebunny/crossref_metadata_2025 huggingface dataset:
Port Recovery through Traffic Operations in the Aftermath of an Oil Spill Incident
Authors: Ali
Published: August 2020

Transportation systems and their components play a substantial role in the U.S. and the world economy. This research study serves as a guide to increase further research or perhaps to continue improving the traffic system in this growing economy. The setting for this research study is an oil spill incident on the Mississippi River near the Port of New Orleans (NOLA). Due to several oil spills in the past, port efficiency is stunted due to delays in the movement of cargo on the roads. The objective of this research study is to develop a quick and efficient solution by using the microscopic simulation platform VISSIM to New Orleans Port operations from being shut down due to an oil spill scenario. The benefits were quantified based on total travel time and total delay along the study corridor. Next, literature on past port oil spills and contingency plans due to oil spills were further researched, as a part of the study to serve as a guide to design the near-perfect plan for execution. The present challenges with the port operations could be alleviated through signal retiming during an oil spill incident. The after study results show the heavy vehicles reduce the delay time. In addition, it also reduce heavy vehicles travel time, provides better heavy vehicles efficiency, and increase overall road network efficiency.
Humans as Midwives for the Earth’s Dark Night of the Soul: A Transpersonal Ecopsychology Perspective
Authors: Butzer Bethany
Published: August 2020

By harnessing fossil fuels for personal use, humans have arguably become the most creative, and the most destructive, species on the planet. Indeed, in order to survive as a species, it is likely that humans need to develop a healthier and more considerate relationship with the ecosystem. Transpersonal ecopsychology is a field that considers these topics by exploring the role of individual transformation in contributing to a larger evolutionary process of psycho-spiritual development – a process that may help humans find their niche in the greater ecosystemic whole. Transpersonal ecopsychology often describes humans as behaving in a destructive fashion that is out of alignment with spiritual principles, and argues that we need to adjust this situation in order to avoid ecosystemic collapse. The current article considers an alternative perspective, namely that human-caused ecological destruction might actually be a sacred and necessary aspect of the spiritual development and transformation of both humans and planet earth. In other words, humans might be undertaking the sacred role of acting as midwives for the earth’s dark night of the soul. While difficult and provocative to consider, this dark night might be necessary for the evolution of human consciousness. This article begins with a description of the role of the dark night of the soul in spiritual awakening, followed by an exploration of the possible human role in midwifing the earth’s dark night, and concludes with a personal reflection on releasing attachment to the outcomes of environmental activism.
Transition dynamics shape mental state concepts
Authors: Thornton Mark Allen , Rmus Milena , Vyas Amisha D. , Tamir Diana
Published: August 2020

People’s thoughts and feelings ebb and flow in predictable ways: surprise arises quickly, anticipation ramps up slowly, regret follows anger, love begets happiness, and so forth. Predicting these transitions between mental states can help people successfully navigate the social world. We hypothesize that the goal of predicting state dynamics shapes people’ mental state concepts. Across seven studies, when people observed more frequent transitions between a pair of novel mental states, they judged those states to be more conceptually similar to each other. In an eighth study, an artificial neural network trained to predict real human mental state dynamics spontaneously learned the same conceptual dimensions that people use to understand these states: the 3d Mind Model. Together these results suggest that mental state dynamics explain the origins of mental state concepts.
Flexible social learning strategies are harder than the sum of their parts
Authors: Dunstone Juliet , Atkinson Mark , Grainger Catherine , Renner Elizabeth , Caldwell Christine Anna
Published: August 2020

The use of ‘explicitly metacognitive’ learning strategies has been proposed as an explanation for uniquely human capacities for cumulative culture. Such strategies are proposed to rely on the use of explicit, system-2 cognitive processes, and to enable advantageous selective copying. To investigate the plausibility of this theory, we investigated participants' ability to make flexible learning decisions under executive function (EF) resource load. Over two studies adult participants completed a simple win-stay lose-shift (WSLS) paradigm task, intended to model a social learning situation where vicarious information can be used to inform response choice, by copying rewarded responses and avoiding those that are unrewarded. This was completed alongside a concurrent EF distractor task. Participants were split into three copying conditions: those that needed to use a flexible copying, WSLS strategy, those that should always copy (information trial always revealed the target), and those that should always do the opposite (information trial always revealed the non-target). The first study found significant effects of EF load and copying condition; the condition demanding a flexible strategy was more challenging than those requiring the use of one rule consistently. In addition, consistently copying was less challenging than consistently avoiding stimuli selected in the information trial. However, each information condition was equally affected by competing executive function demands. The second study found some differences between selectively copying and always copying, as well as effects of memory load, suggesting the impact of EF load on selective copying may stem from working memory requirements. No impact of EF load was found on participants’ metacognitive ability.These results suggest that learning decisions are underpinned by the use of executive functions even at a very basic level, and that selective copying strategies are more challenging than a combination of their component parts. We found minimal evidence that selective copying strategies relied on executive functions any more than consistent copying or deviation. However, task experience effects suggested that ceiling effects could be masking differences between conditions which might be apparent in other contexts. The results also suggest that such contexts might include situations in which information from a social source must be retained in memory.
Re3data.org: Discovery Tool for Reusable Research Data
Authors: Greenberg Charles J , Narang Sangeeta
Published: August 2020

Introduction: Research data is a representation of raw statistical or visual data collected from sources considered vital during a scientific investigation. In the medical sciences, there is enormous data generated from observations, experiments, and clinical investigations. Re3data.org is a global registry of research data, a site supported by DataOne. Re3data.org was originally founded in 2012 and funded by the DFG German Research Foundation, and currently features an international partnership. Discussion: re3data.org currently indexes over 2000 repositories, representing all subjects. In medicine there are 568 listed repositories, divided into 48 sub-categories. A small number of registered repositories are noted as closed, and there are also subjects with no currently listed data repositories. Conclusion: Availability and sharing of research data can facilitate disaster preparedness, model disease transmission, track health outcomes and provide reusable data for new emerging research. Re3data.org provides visibility for existing and emerging open datasets available in a variety of eScience repositories.
THE CHARACTERISTICS OF ASSESSMENT INSTRUMENT FOR CREATIVE THINKING ABILITY ON CRUDE OIL TOPIC
Authors: Monika Nanda Resti Resti
Published: August 2020

The development of globalization era also has an impact on the change in the world of education. The education which is demanded in the learning process is 21st-century learning. One of the important aspects of 21stcentury learning is requiring the students to have the ability to think creatively. Creative thinking ability of the students in the learning process is not apart from the teachers' role. The description of students' creative thinking ability is measured by conducting an assessment. This research aims to know the characteristics of assessment instruments for creative thinking on crude oil topic (construct validity, reliability, the level of difficulty, and question differentiation). This research used Research and Development (R&D) method which referred to Borg and Gall model. The technique of selecting the samples was Purposive Random Sampling. The research samples were 80 students of Grade XII Senior High School in Pekanbaru City. The technique of data analysis used SPSS Program 24.0. The results of the validity construct for each question is > 0,208 with 18 questions are stated valid, the reliability test is 0,846. The percentage level of difficulty obtained 22,222% questions are categorized into easy, 61,111% questions are medium, and 16,667% questions are categorized into difficult. The percentage of question differentiation obtained 16,667% questions are good, 66,667% is fair, and 11,111% is bad.
Model characteristics of technical and tactical actions of skilled defenders in football
Authors: Karpa I. , Ripak I. , Kolobych O. , Gandzin R. , Shanta I.
Published: August 2020

The basis of competitive activity in team play sports, in particular in football are technical and tactical actions. Therefore, football specialists pay considerable attention to defining their model characteristics. It is worth noting that the total number of technical and tactical actions per match for qualified football players, first of all, depends on the class of opponents and the class of players performing these actions. The results of the research allowed us to develop quantitative model characteristics of the competitive activity of the players of the defense of three levels - minimum, average and maximum model, which allows to plan the overall strategy of team preparation, which includes the selection of rational means and methods of preparation, planning of training and competitive loads, as well as the choice of means techniques of game in defense.

The developed model characteristics can serve as criteria for the control of defensive technical and tactical actions in order to improve the system of training the players of the line of defense and operational correction of the competitive activity of the team defenders. The formation of the model characteristics was taken into account the stance of the player and the minimum and maximum indicators of his playing activities both in the matches of the domestic championship and in the Euro-cup matches.

Identifying the correlation between current indicators of volume and the effectiveness of the game action of players of the line of defense with the intensity, responsibility of the game activity, and the characteristics of the opponents' respective actions is a prospect for further research in this direction. In practice, methods of operational correction of game actions during competitions, based on operational control over various parameters of technical and tactical actions and effectiveness of the game of the whole team, are subject to further study and improvement.
Krasushyna T.N. The introducing health-saving methods of physical culture into the system of children under school age education in the family
Authors: Koltsova N.I. , Uzhelina O.N. , Polyukhovych L.I. , Krasushyna T.N.
Published: August 2020

The article deals with the problems of introducing health-saving methods of physical culture into the system of children under school age education in the family. Theoretical and empirical methods of scientific research are determined: analysis of medical-biological, psychological-pedagogical, methodical literature on the introduction of health-saving methods of physical culture into the system of preschool education in the family. It has been researched that health-saving methods are: the conditions of education of the child in the preschool educational institution (absence of stress, adequacy of requirements and methods of education and upbringing); rational organization of the educational process (taking into account age, sex, individual characteristics and hygienic requirements); conformity of educational and physical activity to the child's age; necessary, sufficient and rationally organized motor mode.

It is proved that in order to achieve the goals of health-saving methods of physical culture it is necessary to define the basic means of training: means of motor orientation, health forces of nature; hygienic. Their complex use allows solving problems of pedagogy of health.

In the current literature and practice, health education systems are focused on addressing issues such as: protecting and promoting the health of children; creation of optimum models of planning of educational process, based on the proportional combination of educational load and various types of rest, including active ones; formation of healthy lifestyles in the minds of children and educators.
Status and structure of morbidity of university students
Authors: Kuznietsova O. , Korolevich A. , Filipsky A.
Published: August 2020

The physical education system of the students with chronic diseases, health disorders, congenital anomalies, and low level of physical development and physical fitness, does not sufficiently address efficiency restoration and ensuring normal life. The analysis of literature sources actualized the problem and conclusively proved the need for a comprehensive, systematic study of the health of young students. The aim of the study: to monitor the number of students with health disorders at higher education institutions. The research methods: literary, conceptual and comparative analysis; the analysis of the medical examination of students; pedagogical observation; statistical methods. The object of observation was the students of higher education institutions of a special medical group in the amount of 867 people. Studies conducted for a long time in the educational institution "PolesU", confirmed the superiority of cardiovascular diseases among other pathologies (22.15%). In the 2014/2015 academic year, diseases were recorded in 26.51% of students of the special medical group. The reduction in the number of students enrolled in SMG by the third year indicates that due attention is being paid to correcting their physical condition and improving their health. The largest number of students among those classified by health status as a special medical group was the first-year students.
The use of small forms of active rest to improve the mental capacity of second or third students elementary school classes
Authors: Prysyazhniuk S.
Published: August 2020

This article highlights the effectiveness use of small forms of active recreation to increase mental working capacity of primary school students during the school day. It was found that the students of the second and third grades starting from the second lesson a steady tendency to fatigue of the body develops. Especially children's fatigue developed in math lessons, and in particular if they were scheduled for the third or fourth lesson. The duration of the lesson also contributed to the development of fatigue processes in children of this age 45 minutes, instead of the recommended 40 minutes of the Ministry of Education and Science of Ukraine, because the school bell rang adjusted for all classes 45 minutes Execution of specially selected physical exercises in lessons in the form of a physical education minute or physical education micropause helped reduce the impact of fatigue on the body of children.

One of the urgent problems of modern pedagogy is scientific substantiation of rational motor regime of children and adolescents. Studies in recent years suggest that the cause is the most common diseases, physical development disorders and functional state of the body of schoolchildren is increasingly becoming motor insufficiency experienced by the body of children.
“Dedicated Drop-ins” as a Way of Addressing Some Writing Centre Challenges
Authors: Kaler Michael J.
Published: August 2020

Writing centres need to be integrated into the writing community of their host institutions, but this can be difficult: often students view them as peripheral (Bowles 2019), see them as “fix-it” shops and/or see them as places where one simply “learns to write” (Cheatle & Bullerjahn, 2015; Simpson 2010), or do not perceive a connection between their services and students’ actual, current course work (Missakian, Olson, Black & Matuchniak, 2016). In this article I discuss the practice of offering and running “dedicated drop-ins,” course- and assignment-specific drop-in sessions for writing support, as one means of addressing several of the challenges that writing centres face in terms of making themselves visible and visibly useful members of their institutional community. Our experience shows that while these “dedicated drop-ins” are not in themselves a perfect solution, they can be a useful addition to writing centres’ toolkits.
ANALYSIS OF ENERGY PRICES OF BIOMASS FUEL IN UKRAINE
Authors: Kramar V.G.
Published: August 2020

The purpose of this work is to analyze the energy price change for different kinds of biomass and for natural gas from 2016 to 2020 and to compare it with the relevant trends for countries with a longer experience and  more developed market of fuel biomass. The study revealed that during the significant increase of natural gas price (from June 2016 to December 2018), the energy price of biomass increased at the same or even higher rate than the energy price of natural gas. During the declining natural gas prices (December 2018 to February 2020), when its price almost returned to the situation in mid-2016, the energy price of biomass decreased slightly, but still remains too high, and to date for pellets it is practically equal to the energy price of natural gas. This kind of energy price change for biomass compared to its change for fossil fuels in Ukraine differs significantly from the trends inherent to countries with longer experience of biomass energy use and developed market mechanisms for its pricing (in particular, Austria, Lithuania, Germany, Finland, Sweden). The imperfection of market pricing mechanisms for biomass fuel in Ukraine can be evidenced by the fact that most purchases of biomass in the Prozorro system involve only one supplier. Possible ways to improve the current situation are to promote the creation of more biofuel producers and to improve the conditions for access to raw materials for them, to create a biofuel exchange based on the organizational structure of the Lithuanian biofuel exchange Baltpool, taking into account local conditions.
Colonising ‘Free’ Will
Authors: Forjwuor Bernard
Published: August 2020

While colonialism, in general, is a contested concept, as are the conditions that constitute its negation, political decolonisation seems to be a relatively settled argument. Where such decolonisation occurred, political independence, and its attendant democratic system and the undergirding of the rule of law, signify the self-evidentiality of such political decolonisation. This article rethinks this self-evidentiality of political independence as necessarily a decolonial political accomplishment in Ghana. This critical enterprise opens the documents that founded the newly independent state to alternative reading to demonstrate how the colonial folded itself into the dictate of freedom.
The Future of Representative Politics
Authors: Evans Mihail
Published: August 2020

This paper examines claims made about political representation in recent work on global protest, focusing on two very different authors. Tormey champions the anti-representative claims of various radical movements while Krastev assumes the stance of those political insiders who deplore the failure of protesters to work within established representative institutions. Both turn to examples which seem to best support their positions. Tormey to anarchist inspired movements in Spain and Mexico, his argument being that political representation has been succeed by what he variously calls ‘immediate representation’ and ‘resonance’. Krastev’s focus is Russia, Thailand and Bulgaria. His argument is that protest in these countries can be seen are ‘a collective act of exit’ by middle classes that no longer seek political representation. Using the theorisation of political representation in Rosanvallon’s Counter Democracy, I suggest that the global waves of protest of recent years are nothing inherently novel but can be seen as part of the elaborate and complex process of representation that is argued to have always existed beyond and outside of official elected legislative bodies. In conclusion, I suggest that Macron’s turn to citizen’s assemblies can be seen as informed by just such an understanding of political representation.
Interpretacija pokopališč kot del turistične ponudbe: primer dobre prakse
Authors: Ostrman Renault Tanja
Published: August 2020

Ljudje imamo nekaj skupnih točk, in ena teh točk je smrt, kateri se nihče ne more izogniti. Fascinacija s tem zadnjim dejanjem življenja, filozofije in religije, ki so razlagale življenje po smrti in rituali, ki iz njih izhajajo, so bili zmeraj v središču človekove pozornosti. Toda ali lahko to zadnje dejanje postane turistična atrakcija? Članek se osredotoča na majhno in neznano pokopališče na Aljaski kot na študijo primera, da bi pokazali, kako lahko pokopališča nudijo različne možnosti za interpretacijo. Podatke smo pridobili na internetu in z metodo opazovanja z udeležbo na potovanju po Aljaski in ogledu mesta in pokopališča Skagway.
DSCAM-AS1 accelerates cell proliferation and migration in osteosarcoma through miR-186-5p/GPRC5A signaling
Authors: Ning Yuwen , Bai Zhengfa
Published: August 2020

Osteosarcoma (OS) is one of the most primary bone malignancies, often occurring in adolescents or children. Numerous scientific findings have introduced that long noncoding RNAs (lncRNAs) can be involved in tumor occurrence and development. Although DSCAM-AS1 has been studied in several cancers, its role and mechanism in OS are poorly understood. In this work, high level of DSCAM-AS1 was validated in OS cell lines. Depleting DSCAM-AS1 inhibited cell proliferation, migration and EMT process in OS. Subsequently, we disclosed that DSCAM-AS1 was mainly observed in the cytoplasm of OS cells and could bind with miR-186-5p in OS. Moreover, inhibiting miR-186-5p rescued the impact of silenced DSCAM-AS1 on OS progression. Additionally, GPRC5A was verified as the target downstream of miR-186-5p, and it was negatively modulated by miR-186-5p but positively regulated by DSCAM-AS1. More importantly, DSCAM-AS1 enhanced GPRC5A level in OS by sequestering miR-186-5p. Finally, up-regulating GPRC5A reversed the influences of DSCAM-AS1 repression on the oncogenic behaviors of OS cells. Knockdown of DSCAM-AS1 suppressed NPC tumor growth in vivo. All findings uncovered that DSCAM-AS1 aggravated OS progression through sponging miR-186-5p to up-regulate GPRC5A expression. Thus, we proposed DSCAM-AS1 as a probable target for OS treatment.
Upregulated histone deacetylase 2 gene correlates with the progression of oral squamous cell carcinoma
Authors: Krishna Akhilesh , Singh Vineeta , Singh Shraddha , Kumar Sachil , Kumar Vijay , Mehrotra Divya , Singh Uma Shankar , Mahdi Abbas Ali
Published: August 2020

BACKGROUND: Histone deacetylases (HDACs) are considered as an essential regulator of cellular proliferation, differentiation, and apoptosis. The HDAC2 enzyme of Class I HDACs plays an important role in tumor progression of human malignancies. OBJECTIVE: The aim of the present study was to analyze the HDAC2 gene expression in pre-oral cancer and oral squamous cell carcinoma (OSCC), and its association with clinico-pathological features. METHODS: The HDAC2 protein expression was analyzed through the immunohistochemistry and western blot techniques in 82 oral pre-malignant, 90 OSCC, and 16 normal control tissues. qRT-PCR was used to quantify the mRNA fold change in all groups. RESULTS: The HDAC2 protein and mRNA levels were significantly higher in OSCC and pre-oral cancer groups compared to the controls. Immunostaining of HDAC2 protein was enhanced in 84.4% of OSCC and 67.1% of pre-cancerous tissue sections (p< 0.01). The mean protein level was analyzed as 1.96 ± 0.44 in oral carcinoma, 1.61 ± 0.39 in pre-cancer and 0.96 ± 0.10 in control tissues. In addition, HDAC2 mean protein level was associated with histological differentiation (OR = 25, p< 0.05) and tumor-node-metastasis (TNM) stages (OR = 6.2, p< 0.05) of OSCC patients. CONCLUSIONS: The upregulated HDAC2 gene in pre-cancer and OSCC tissues indicates its crucial role in the transformation of pre-malignant to malignant carcinoma. It could be a potential cancer biomarker of prognosis and targeted therapy in OSCC.
Circ_0007031 enhances tumor progression and promotes 5-fluorouracil resistance in colorectal cancer through regulating miR-133b/ABCC5 axis
Authors: He Xiaowen , Ma Jun , Zhang Mingming , Cui Jianhua , Yang Hao
Published: August 2020

Colorectal cancer (CRC) remains one of the most commonly diagnosed malignancies worldwide. Circular RNAs (circRNAs) are being found to play crucial roles in human cancer, including CRC. The purpose of this study was to explore the function and mechanism of circ_0007031 on CRC progression and 5-fluorouracil (5-FU) resistance. The levels of circ_0007031, ATP-binding cassette subfamily C member 5 (ABCC5) and miR-133b were assessed by quantitative real-time polymerase chain reaction (qRT-PCR) or western blot. Cell survival and proliferation were detected by the 3-(4,5-dimethylthiazol-2yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium (MTS) assay. Cell colony formation was evaluated using a standard colony formation assay. Transwell assays were performed to determine cell migration and invasion. Targeted correlations among circ_0007031, miR-133b and ABCC5 were verified by dual-luciferase reporter, RNA immunoprecipitation (RIP) and RNA pulldown assays. Animal experiments were performed to observe the role of circ_0007031 in vivo. Our data indicated that circ_0007031 up-regulation was associated with CRC resistance to 5-FU. Circ_0007031 knockdown repressed CRC cell proliferation, migration and invasion and enhanced 5-FU sensitivity. Circ_0007031 directly interacted with miR-133b. Moreover, circ_0007031 knockdown regulated CRC cell progression and 5-FU sensitivity by miR-133b. ABCC5 was a direct target of miR-133b, and circ_0007031 mediated ABCC5 expression via acting as a miR-133b sponge. Furthermore, miR-133b overexpression regulated CRC cell progression and sensitivity to 5-FU by down-regulating ABCC5. Additionally, circ_0007031 knockdown suppressed tumor growth in vivo. Our current work had led to the identification of circ_0007031 knockdown that repressed CRC cell malignant progression and enhanced 5-FU sensitivity via regulating ABCC5 expression by sponging miR-133b.
Multi-stage deep learning perception system for mobile robots
Authors: Macias-Garcia Edgar , Galeana-Perez Deysy , Medrano-Hermosillo Jesus , Bayro-Corrochano Eduardo
Published: August 2020

This paper presents a novel multi-stage perception system for collision avoidance in mobile robots. In the here considered scenario, a mobile robot stands in a workspace with a set of potential targets to reach or interact with. When a human partner appears gesturing to the target, the robot must plan a collision-free trajectory to reach the goal. To solve this problem, a full-perception system composed of consecutive convolutional neural networks in parallel and processing stages is proposed for generating a collision-free trajectory according to the desired goal. This system is evaluated at each step in real environments and through several performance tests, proving to be a robust and fast system suitable for real-time applications.
Synthesis and anti-tumor properties of derivatives [4- (41-chlorophenyl)-5,6,7,8-tetrahydro-2,2a,8a-triazacyclopenta[c,d]azulen-1-yl-metil]-para-tolylamine
Authors: Demchenko S. A. , Sukhoveev V. V. , Моsкаlеnко О. V. , Fedchenkova Yu. A. , Potebnia G. P. , Demchenko A. M.
Published: August 2020

Leukemia, as a part of hemoblastosises, is a malignant blood system disease, which is characterized by bone marrow damage, caused by leukemic stem cells, which appear due to disruption of self-renewal and differentiation of hempoetic stem cells and predecessor cells. In their turn, hemoblastoses are divided into two groups: bone marrow (acute leukemia, chronical leukemia, paraproteinemic hemoblastoses) and outside bone marrow (lymphogranulomatosis, or Hodgkin lymphoma, and non-Hodgkin malignant mymphomas).
Nowadays in Ukraine, different kinds of leukemia are cured by various drugs, which have many side effects. Increase in effectivity of chemotherapy of tumor disease is primarily related to creation of new antitumor drugs of selective action. Which is why search for biologically active compounds with antitumor activity is a perspective direction in creation of new drugs.
Aim of this work was synthesis of compounds with potential antitumor properties in a variety of [4-(41-chlorophenyl)-5,6,7,8-tetrahydro-2,2a,8a-triazacyclopenta[c,d]-azulen-1-yl-methyl]-para-tolylamin derivatives.
As the objects of our studies, we have picked the derivatives of [4-(41-chlorophenyl)-5,6,7,8-tetrahydro-2,2а,8а-triazacyclopenta[c,d]-azulen-1-yl-methyl]-para-tolilamin (8 and 10 a, b). [4-(41-Chlorphenyl)-5,6,7,8-tetrahydro-2,2а,8а-triazacyclopenta[c,d]azulen-1-yl-methyl]-para-tolylamin (8) was obtained by boiling of equimolar quantities of 3-(41-methylphenyl)aminomethyl-6,7,8,9-tetrahydro-5Н-[1,2,4]triazolo[4,3-a]azepin (5) and α-brom-4-chloracetophenon in ethylacetate. Thioamides (10 a, b) were obtained by interaction of amin (8) with corresponding arylisothiocyanates (9 а, b) in dry benzene.
Antitumor activity of [4-(41-chlorphenyl)-5,6,7,8-tetrahydro-2,2а,8а-triazacyclopenta[c,d]azulen-1-yl-methyl]-para-tolylamin (8) was studied in National Cancer Institute of Health, USA within Development Therapeutic Program.
In experimental conditions [4-(41-chlorphenyl)-5,6,7,8-tetrahydro-2,2а,8а-triazacyclopenta[c,d]azulen-1-yl-methyl]-para-tolylamin (8) showed ability to inhibit growth of cancerous leukemia cells of CCRF-CEM, HL-60(TB), K-562, MOLT-4, RPMI-8226 and SR lines, higher than standard – 5-fluorouracil. Towards HL-60(TB) cells [4-(41-chlorphenyl)-5,6,7,8-tetrahydro-2,2а,8а- triazacyclopenta[c,d]azulen-1-yl-methyl]-para-tolylamin exceeds standard in effectivity by 64.68%. For K-562, MOLT-4, RPMI-8226 and SR cells, those numbers are equal to: 85.88%, 84.95%, 42.10% and 36.82% correspondingly. Towards CCRF-CEM cells, this compound not only inhibits cell growth and division, but also destroys them by 20.34%.
Thus conducted studies confirm perceptivity of search for compounds with antitumor action on the basis of [4-(41-chlorophenyl)-5,6,7,8-tetrahydro-2,2а,8а-triazacyclopenta[c,d]azulen-1-yl­methyl]-para-tolylamin.
PENGARUH BRIDGING EXERCISE TERHADAP SPASTISITAS PADA PASIEN PASCA STROKE NON HEMORAGIK DI MAKASSAR
Authors: Ramba Yonathan , Hendrik Hendrik
Published: August 2020

troke adalah terjadinya gangguan fungsional otak fokal maupun global secara mendadak dan akut yang berlangsung lebih dari 24 jam, akibat gangguan aliran darah otak. Stroke terbagi menjadi dua kelompok, yaitu Stroke Non Hemoragik (NHS) dan Stroke Hemoragik (HS). Stroke Non Hemoragik (NHS) adalah jenis stroke yang disebabkan oleh trombosis akibat plak arterosklerosis dari arteri otak atau yang memberi vaskularisasi pada otak atau suatu embolus dari pembuluh darah di luar otak yang tersangkut di arteri otak.Tujuanpenelitianadalahuntuk mengetahui pengaruh antara pemberian bridging exercise terhadap spastisistas pada pasien pasca Stroke Non Hemoragik  di  Makassar.Penelitian ini merupakan penelitian  pra-eksperimental  dengan  Desaign  One Group Pretest – Post Test  untuk mengetahui perbedaan spastisitas sebelum dan sesudah pemberian  bridging exercise pada pasien pasca Stroke Non-Hemoragik di Makassar.  Populasi dalam  penelitian ini adalah seluruh pasien Stroke Non Hemoragik yang datang berobat di Rumah Sakit Umum Daerah Daya Kota Makaassar, Klinik Physio Sakti dan Klinik Medisakti.Berdasarkan hasil uji hipotesis dengan Uji Wilcoxon ditunjukan bahwa terdapat perbedaan yang signifikan pada pasien pasca Stroke Non Hemoragik antara pengukuran pre test, dan setelah 6 kali pemberian bridging exercise. Jadi dengan pemberian bridging exercise pada pasien pasca Stroke Non Hemoragik dapat memberikan efek perubahan penurunan spastisitas.Setelah 6 kali pemberian bridging exercise, penurunan spastisitas semakin nyata,  3 orang responden dengan kategori  Modified Skala Ashwort normal(17,6%) , 12 orang responden dengan kategori Modified Skala Ashwort sangat ringan (70,6%), dan 2 orang  responden dengan kategori Modified Skala Ashwort ringan (11,8%). Kata kunci : Bridging exercise, Spastisitas, Pasca Stroke Non-Hemoragik.
Relaciones sanas. Guía para la prevención de la violencia en las relaciones de pareja joven
Authors: Lara laura , Providell Lesliee , Labra Paloma
Published: August 2020

El inicio de las relaciones de pareja conlleva una serie de cuestionamientos sobre qué es lo que se debería esperar en ellas. La verdad es que no hay una sola forma de comportarse en las relaciones, pero sí, a partir del conocimiento científico disponible, se puede orientar en los aspectos que deberían estar presentes y los que no. Por tanto, esta guía surge como una forma de acercar este conocimiento a los y las jóvenes de una manera atractiva y directa, para ayudar a que el establecimiento de estas relaciones se realice de modo que permita su disfrute, evitando situaciones negativas que puedan dar lugar a dinámicas abusivas.
Research on the Construction Mode of Enterprise Colleges
Authors: Zhao Keyan
Published: August 2020

A vocational college focuses on the training of high-quality technical personnel. The outline of the national plan for medium and long-term education reform and development clearly states that enterprises and other social forces should be encouraged to participate in running schools. Quality educational resources should be expanded, and the efficiency of running schools should be improved. The enterprise college can combine the superior resources of the enterprise and the superior resources of the college to promote the reform of the teaching mode of the college, to provide the society with high-quality skilled talents, and to improve the teaching quality of the college. Based on this, this article explores the construction mode of enterprise colleges, hoping to provide a reference for the reform of college teaching mode and make a contribution to the healthy development of colleges.
La recepción de la imagen de las mujeres en los medios: una aproximación cualitativa
Authors: García Muñoz Nuria , Martínez García Luisa
Published: August 2020

Este artículo tiene como objetivo analizar los resultados de una investigación sobre el consumo femenino de los estereotipos de género presentes en los medios de comunicación. Nos interesa conocer cuáles son los estereotipos de género que las mujeres valoran como discriminatorias y cuáles consideran como prácticas positivas respecto a la imagen de la mujer en la sociedad. Pretendemos generar pautas de conocimiento en tres vertientes: en la percepción y consideración de la ciudadanía frente a los contenidos mediáticos, comprensión de la participación social referente a dichos contenidos, y la valoración, efectividad y otras acciones que pueden ayudar a mejorar la representación de las mujeres en los medios de comunicación.
El mundo de los periodistas: aspectos teóricos y metodológicos
Authors: Henrique Pereira Fabio
Published: August 2020

El artículo se propone discutir la pertinencia de la noción sociológica de "mundo social" aplicada a los estudios de periodismo. Basado en la tradición del interaccionismo simbólico, este concepto es generalmente utilizado para analizar los fenómenos socialmente reconocibles, sin necesidad de estar situados en un espacio institucionalizado. En este caso, se entiende que la comprensión sobre el periodismo no puede limitarse a las prácticas de la producción noticiosa, sino que abarca diferentes esferas sociales. El concepto permite escapar de una visión esencialista sobre el periodismo, situándolo como una realidad socialmente construida a partir de la interacción simbólica entre los diferentes actores.
Historia y comunicación social: apuntes para un diálogo inconcluso. Aproximación crítica al campo de estudios históricos en comunicación
Authors: Amaya Trujillo Janny
Published: August 2020

The central purpose of this article is to offer a critical approach to the development of the historical studies in communication, and its position into the communication research field. Also, the author tries to show some of the most important limitations and constrictions inherited and reproduced in this field of studies. It offers a synthesis of the main challenges of this area, and its epistemological projections to the communication field.
Los límites cambiantes de la vida pública y la privada
Authors: Thompson John B.
Published: August 2020

La proliferación de nuevas tecnologías de comunicación de hoy, nos obliga a reconsiderar la naturaleza de la vida pública y privada y las cambiantes relaciones entre éstas. En las sociedades contemporáneas los límites entre lo público y privado se confunden y cambian constantemente. Thompson utiliza su teoría social de los medios para desarrollar una nueva perspectiva sobre la distinción entre lo público y lo privado en donde las fronteras que existen en cualquier punto en el tiempo son porosas, discutibles y sujetas a constante negociación y lucha; una situación que se ilustra vívidamente por el fenómeno del escándalo político.
Comunicación pública, transición política y periodismo en México: el caso de Aguascalientes
Authors: De León Salvador
Published: August 2020

A través de la relación entre periodistas, propietarios de medios, políticos y relacionistas de las fuentes políticas, en el texto se analiza la comunicación pública en Aguascalientes. Los hallazgos se vinculan con las transformaciones políticas y la apertura económica ocurridas en México desde la década de 1990. La discusión refiere el modo en el que se configura la comunicación pública en sociedades en transición, como la mexicana.
Re-visitando los estudios de recepción/ audiencias en Colombia
Authors: Bonilla Vélez Jorge Iván
Published: August 2020

El propósito del artículo es analizar algunas continuidades, desplazamientos y rupturas en los estudios de recepción y audiencia en Colombia durante las últimas cinco décadas. Se plantea que los estudios sobre la recepción/ audiencias han perdido su vínculo político, el cual ha sido sustituido por una vocación pedagógica interesada en la recepción crítica de medios. Esto ha marchado paralelo a un desplazamiento de los sujetos populares a los sujetos infantiles y juveniles en este tipo de estudios.
Televisión y producción de interacciones comunicativas
Authors: Orozco Gómez Guillermo
Published: August 2020

El presente ensayo retoma preguntas y temas centrales, que en su momento, 1987, motivaron la preparación del texto: Televisión y Producción de Significados, ensayo en tres partes, que inaugurara la entonces naciente revista Comunicación y Sociedad, cuyos 25 años se conmemoran en este número. A la vez, este ensayo avanza, contextualiza y proyecta esas viejas preocupaciones en la “condición comunicacional” contemporánea, mediada más que nunca por la tecnología y el mercado, resultando en una creciente cultura y comunicación del entretenimiento.
Escenas de lectura e industria cultural: el caso de los libros de autoayuda
Authors: Canavire Vanina Belén
Published: August 2020

En este artículo abordamos un género de particular relevancia en el mercado editorial mundial: la literatura de autoayuda. Teniendo como escenario una ciudad argentina, y mediante el análisis de representaciones, experiencias y prácticas lectoras, recuperamos singulares apropiaciones de los libros de autoayuda, revelando finalmente la trama que se entreteje con el sistema de las industrias culturales.
La mediación familiar en la recepción televisiva infantil: análisis de los indicadores de mediación preferente y efectiva
Authors: Torrecillas Lacave Teresa
Published: August 2020

Apoyados en entrevistas en profundidad a 48 familias con hijos de entre 4 y 12 años de la comunidad de Madrid, hemos analizado cada uno de los indicadores que definen el proceso de mediación de los padres en las prácticas televisivas de los hijos. Se ha revelado un alto grado de permisividad en los hogares y la necesidad de educación mediática de los padres.
Ciudadanía política en la red. Análisis de las prácticas políticas entre jóvenes universitarios
Authors: Padilla De la Torre María Rebeca
Published: August 2020

Internet adquiere de manera creciente un papel relevante en las prácticas políticas actuales. En este estudio se analizaron las llevadas a cabo por universitarios, a través de sus propios registros en diarios en línea. Los hallazgos contribuyen a la discusión sobre la apropiación de esta tecnología para el ejercicio de su ciudadanía política.
Decisiones públicas sin diálogo público: análisis de los argumentos sobre el caso de la Vía Exprés vertidos en la prensa de Guadalajara
Authors: Acosta García Raúl Gerardo , Larrosa-Fuentes Juan , Paláu Cardona María Magdalena Sofía
Published: August 2020

Este artículo presenta cómo se discutió la posible realización de una obra pública en Guadalajara. La obra, que no fue realizada, enfrentó a actores políticos y sociales. La investigación estudió cómo se construyó el diálogo público en cuatro diarios. A través del análisis de contenido de notas y opiniones publicadas y de los argumentos vertidos en ellas, los autores dan cuenta de la baja calidad del diálogo público.
La subtitulación aficionada de animación japonesa: una aproximación intertextual
Authors: Echeverría Arriagada Carlos I.
Published: August 2020

El presente artículo constituye una aproximación a la subtitulación aficionada de animación japonesa (saaj) desde la perspectiva de la intertextualidad. Se busca, en lo esencial, mostrar la idoneidad del marco teórico adoptado para el estudio de actividades discursivas de la compleja naturaleza de la saaj y proporcionar la base para una consideración adecuada de esta práctica en particular.
Aro Tolbukhin y la superposición de los niveles ficcionales
Authors: Sanabria Carolina
Published: August 2020

El presente artículo trabaja con el atípico filme Aro Tolbukhin. Dins la Ment de l’assassí (2002) de Agustí Villaronga, Lydia Zimmermann e Isaac P. Racine, donde destaca la desarticulación de los códigos del género documental para evidenciar la imposibilidad de referirse a lo real sin aludir a la ficción. Enunciadas desde diversas perspectivas en superposición desde usos no cronológicos que dan cuenta de una nueva manera de narrar dentro del panorama del cine español, estos niveles ficcionales se confunden entre sí en función de una óptica donde lo idílico se combina con lo atroz.
Books and culture in the digital age
Authors: Thompson John B.
Published: August 2020

Entrevista a John B. Thompson
El slacktivismo como recurso de movilización en redes sociales: el caso de #BringBackOurGirls
Authors: Córdoba Hernández Ana María
Published: August 2020

Este trabajo estudia el desarrollo de la campaña #BringBackOurGirls en Twitter, durante 2014, a través de seis APIs de medición de redes sociales. El objetivo es aproximarse a las ventajas que supone el Slacktivismo, como fenómeno de movilización social en Internet, desde los presupuestos de la Teoría de Movilización de Recursos (TMR) y su efectividad para impactar la agenda política mundial.
Flujos metodológicos desde el Sur latinoamericano. La zona de la comunicación y las Metodologías Horizontales
Authors: Corona Berkin Sarah
Published: August 2020

En este artículo, dar vuelta al mapa implica rediseñar las representaciones del poder. Invertir la tradicional visión de los flujos de pensamiento para colocar, de otro modo, la investigación en comunicación y cultura, visibiliza un conjunto de investigaciones que vienen del Sur y que han dado forma a un pensamiento latinoamericano que desarrolla sus propias teorías y metodologías. La historia de los flujos de las teorías latinoamericanas se actualiza en este artículo, con las Metodologías Horizontales como propuesta para construir nuevo conocimiento en comunicación y cultura.
La telenovela en mexico: ¿de una expresión cultural a un simple producto para la mercadotecnia?*
Authors: Orozco Gómez Guillermo
Published: August 2020

Se enfatizan en este ensayo algunos de los principales cambios que el formato de la ficción televisiva ha ido sufriendo desde sus orígenes, como relato marcado fuertemente por la cultura y los modelos de comportamiento característicos de su lugar y su época. En este recorrido se hace referencia a la telenovela “Rebelde” producida y transmitida por Televisa en México a partir de 2005. El análisis destaca el tipo de transformaciones formales, estéticas y narrativas que el formato de la telenovela está teniendo y sobre todo su mercadotecnia, argumentos que ayudan a explicar ese fenómeno emergente por el cual la telenovela empieza a “no ser vista” por la audiencia, sino solamente consumida, “comprada”.
El “análisis de los marcos” en el discurso de Bush (septiembre 11 de 2001)
Authors: Chihu Amparán Aquiles
Published: August 2020

El objetivo de este trabajo es el de describir y analizar el discurso empleado por el presidente George Bush en la coyuntura del atentado terrorista del 11 de septiembre de 2001. Con este propósito analizo las estrategias discursivas empleadas por los principales actores involucrados para justificar una guerra contra sus adversarios. Como método, en el estudio de discurso, aplico el “análisis de los marcos” (frame analysis); “enmarcar” (framing) significa seleccionar determinados aspectos de la realidad percibida en un texto, para con este propósito promover una definición del protagonista, del antagonista, del problema y recomendar alternativas para la solución del problema.
Todas las industrias son culturales: crítica de la idea de “industrias culturales” y nuevas posibilidades de investigación
Authors: Mato Daniel
Published: August 2020

Aunque las categorías “industrias culturales” y “consumo cultural” resultan útiles en valiosas publicaciones, no están exentas de problemas. Este texto muestra cómo su uso obstruye algunas posibilidades de investigación y cómo dejar de usarlas abre nuevas posibilidades. Destacar el atributo “cultural” de algunas industrias y consumos, en particular, oculta la relevancia cultural de todas las demás industrias y consumos, y así se obstaculiza el estudio de otras industrias y consumos desde perspectivas culturales.
La alfabetización audiovisual entre adolescentes vascos: implicaciones para las prácticas educativas y propuesta de intervención
Authors: Zarandona de Juan Esther , Basterretxea Josi , Idoyaga Petos , Ramírez de la Piscina Txema
Published: August 2020

En este trabajo se presentan algunos resultados de una investigación desarrollada por profesores de la Euskal Herriko Unibertsitatea–Universidad del País Vasco (EHU–UPV) durante el periodo 2003–2005. Los objetivos han sido: averiguar el nivel de equipamiento tecnológico de los adolescentes vascos; conocer el consumo que realizan de las diferentes tecnologías de la información y la comunicación; escrutar sus hábitos culturales e investigar, en definitiva, su grado de alfabetización audiovisual.