bluuebunny/crossref_metadata_2025 huggingface dataset:
Equity in Learning Opportunities for Middle School Students: Connecting Communities and Transportation Through GIS
Authors:   California State University, Long Beach, O’Brien Tom , Olson Ben ,   California State University, Long Beach
Published: September 2023

Geographic information systems (GIS) is part of an in-demand career skillset that can lead to safer streets in California communities. This project included a three-session bootcamp that introduced middle school students to transportation via GIS and gathered assessments on their awareness of transportation as a career pathway. The project built upon CSUTC TRANSPORTS’ Year 4 project, “K–12 Special Investigation Project: Mapping E-Commerce Locally and Beyond.” The bootcamp for this project was coordinated in partnership with Rio Hondo College, which provided the instructor and connection to the students at the Mountain View Unified School District in El Monte, CA. The bootcamp focused on developing safer communities and transportation systems as a context for the students to become familiar with GIS. The student feedback reported on student awareness of transportation and GIS prior to the bootcamp and how the curricular tools and activities impacted that awareness. Gathered data and feedback will inform the development of future middle school GIS curricula, an area that is underdeveloped.
Analysis of the tendencies and dynamics of electronic receipt prescribing for antibiotics and their electronic dispensing in Ukraine and Lviv region
Authors: Блавацька О. Б. , Яцкова Г. Ю. , Сосновська Г. О.
Published: September 2023

Uncontrolled use of antibiotics (antibacterial, antimicrobial agents) leads to the growth of antibiotic resistance, which has become a global health problem. E-prescribing should increase the population's access to medical and pharmaceutical care.

The purpose of the study: to establish the general trends of electronic prescribing of antibacterial drugs in Ukraine since its introduction in August 2022 and the impact of receipt e-prescribing on the controllability of antibiotic use, as well as to analyze the dynamics of the number of prescribed and dispensed electronic prescriptions for antibacterial drugs.

We used the following research methods: informative, comparative and retrospective analysis of the dynamics of e-prescriptions for antibiotics. For this purpose, we used the e-data dashboards of the National Health Service of Ukraine (NHSU) and the data of the ENT KP «Pharmacy No.1» in Lviv for the period 08. 2022–05. 2023.

In general, Lviv region is consistently in the top three, five or ten regions according to certain indicators. It was established that Lviv region is on the third place in Ukraine in terms of the number of issued e-prescriptions for antibiotics, on the first place in terms of the number of dispensed specified prescriptions, but in terms of the ratio of the number of issued e-prescriptions to those issued, Lviv region is in tenth place. The e-data of the National Health Service of Ukraine shows the nomenclature and number of electronic prescriptions of antibacterial drugs, the number of e-prescriptions that have been released, which are registered in the e-healthcare system. However, during the period of martial law, data on antibacterial drugs dispensed according to paper prescriptions or information certificates, equivalent to them, are not recorded. Thus, the e-data reflect the actual consumption of only those antibiotics that are recorded through the redemption of e-prescriptions, i.e. cover only one prescription segment.

It is shown that although e-prescribing increases the control over the prescription of antibiotics, however, in force majeure circumstances of wartime, e-dispensing does not reflect the real picture of antibiotic consumption in general, but only one segment that is recorded in the e-system of health care. However, it is impractical to introduce an exclusively electronic prescription for antibiotics under martial law, as this carries the risk of limiting access to medical care. The use of the e-system allows to establish control over the quantitative indicators and assortment composition of antibiotics prescribed by doctors, which is definitely a necessary stage for improving the rational use of antibacterial drugs and combating antibiotic resistance.
Evaluation of grain and forage yield and forage quality traits in some hybrid maize genotypes cultivated as second crop under the Eastern Mediterranean conditions
Authors: ERTEKİN İbrahim , KONUŞKAN Ömer , ATIŞ İbrahim
Published: September 2023

This research was conducted in order to guide farmers and researchers by determining grain, forage yield and yield-related traits and forage quality of different parts of the whole plant in some maize cultivars in Eastern Mediterranean ecological conditions. In this study, it was assessed grain and forage yield and fodder quality of four maize cultivars (PR91G98, SY Castaneda, SY Gladius, and SY Tuscani) cultivated under the Estern Mediterranean conditions. To determine forage quality, ear, stem and leaves of the whole plant maize were analyzed separately. To evaluate grain and forage yield, parameters like plant height, stem diameter, hay yield, dry matter yield, green leaf yield, green stem yield, ear weight, green ear yield were investigated while features such as crude protein, crude ash, organic matter, NDF, ADF, digestibility of dry matter, dry matter intake and relative feed value were examined to determine forage quality. The new maize cultivars have been updated continually; it is important to clarify the responses of new varieties to agronomic practices and forage yield, quality, grain yield, and related traits. The results of this study revealed that ear is very important for forage yield and quality. The greatest hay and grain yield were produced by PR31G98 maize cultivar. It was observed SY Tuscani had higher NDF and ADF values than other maize varieties. With this study, the importance of nutrient content according to silage yield and plant parts in second crop corn cultivation was determined. In addition, research results showed important source data for farmers and researchers regarding forage and grain yield of maize farming and production area is continually increasing.
Acceptance and Application Process of the Ecomuseum in Korea: From Cheoram Villageum to Cheoram Coal Mine History Town
Authors:   Academic Association of Global Cultural Contents, Bae Eun Sok
Published: September 2023

Cheoram in Gangwon-do is the place where was once very active as a coal mining area in the 1970s and 1980s, but experienced a decline, suffering a crisis of being turned into an abandoned mine since the 1990s. Cheoram Villageum is very noteworthy in that it has embraced the concept of the ecomuseum among the voluntary movements of residents to revitalize the community. This can be regarded as the first acceptance and application of the ecomuseum concept in Korea. This paper investigates the whole current activities of the coal mining town of Cheoram, which has marked a very important beginning in the history of ecomuseums in Korea, starting from Cheoram Villageum. This leads to how ecomuseums earlier in Korea were introduced and how their experimental efforts had an effect on the local areas. Since the ecomuseum is a concept responsible for an important axis of local culture as it is born and grows like a living organism, it is necessary to observe the transition of change while watching it for a long time. The course of examining changes in Cheoram begun in 1998 may be a significant study in its own right. Cheoram Coal Mine History Town currently in operation is also researched and analyzed using the MACDAB index. In addition, while thinking about future improvements, it is suggested that Cheoram Coal Mine History Village establishes itself as a genuine ecomuseum and exchanges with ecomuseums around the world that started in mining towns.
Medical (doctor’s) error: concept and causes of its occurrence
Authors: Skrynnikova K. O.
Published: September 2023

The concept of “medical (doctor’s) error” is analysed from the doctrinal standpoint. The existing approaches (legal and medical) to defining the legal nature of a medical (doctor’s) error have been considered. It has been argued that this topic is of great theoretical and practical importance, since errors and negligence of doctors and medical staff can cause irreparable harm to patients' health or lead to death. The problem is complex, because it requires both medical and legal knowledge, and is related to the most important and difficult issue of qualifying certain acts. It has been concluded that the term “medical (doctor’s) error” is the most appropriate one, but it is absent in Ukrainian legislation. It has been proposed to introduce appropriate amendments to the legislation in the field of medicine and to enshrine the concept of “medical (doctor’s) error”, types and causes of its occurrence legally. The main characteristics of the category of medical (doctor's) error have been substantiated, and its content has been defined.

The reasons for the occurrence of medical errors have been analysed. The subjective and objective reasons that influence the actions (inaction) of doctors and medical professionals have been identified. The classification of medical (doctor’s) error according to various criteria has been studied. Certain types of such errors are identified, in particular: diagnostic; therapeutic and tactical; technical; organisational; deontological.

A legal assessment of a medical (doctor’s) error as one of the possible grounds for civil liability has been provided. It has been substantiated that the liability of a doctor and medical staff depends on the presence of fault in their actions and the qualification of the negative result of medical care. In addition, scientifically grounded proposals and recommendations for improving the civil legislation of Ukraine in the field of medical activity have been provided.
Teorías actuales acercade los procesos neurodegenerativos de la enfermedad de Alzheimer
Authors:   Departamento de Ciencias de la Salud, Centro Universitario Tonalá, Universidad de Guadalajara, Tonalá, México, Rangel González Fátima
Published: September 2023

La enfermedad de Alzheimer es un tema de gran relevancia actualmente, por lo tanto es muy importante tener en cuenta las teorías que hasta ahora se conocen acerca de los daños neurológicos de esta enfermedad. Aun no se tiene una causa específica que explique esta enfermedad en su totalidad, sin embargo se tienen datos de investigaciones anteriores de esta enfermedad que tiene como etiología neurodegenerativa diversos factores como la acumulación del péptido ȕ- amiloide, que contribuye a la degeneración de neuronas; los ovillos neurofibrilares favorecen la acumulación y formación de agregados; el estrés oxidativo afecta la actividad de los canales iónicos y transportadores; los factores genéticos también juegan un papel muy importante en esta enfermedad. Se conocen hasta la actualidad tres genes que están asociados a formas preseniles autosómicas dominantes: el gen que codifica para la proteína precursora del péptido beta-amiloide (APP), el gen de las presenilinas (PSEN1 y PSEN2), hay un cuarto gen, el de la apolipoproteina E (APOE), y por último la inflamación, es otro de los factores neurodegenerativos, ésta involucra diversas molé-culas como IL-1ȕ, TGF- ȕ y COX-2 cerebrales que se encuentran elevadas en la EA.
Gender-based cyber violence and 8M 2021 in Tampico, Tamaulipas: comments and its reach on Facebook
Authors:   El Colegio de Tamaulipas, Domínguez Arteaga Rosa Amelia
Published: September 2023

Information and communication technologies (ICT) are allied in the expansion of the feminist movement, however, they have also become its enemies due to the present cyber-violence towards the movement. This study aims to explore the comments on the 8M 2021 march in Tampico, Tamaulipas, posted on the Facebook platform. For this purpose, a content analysis was conducted, based on previous studies focused on social networks. As part of the results, we found mostly sarcastic comments against the march, related to gender violence on the network. Since these expressions seek to silence feminists and co-opt their right to demonstrate, it is concluded that this cyber-violence is a sign of the gender-based political violence experienced by this group.
Derive observable ocean climate indicators from seasonal forecast
Authors: Balmaseda Magdalena A. , McAdam Ronan
Published: September 2023

Derive the user-relevant indicators defined in Milestone MS7 from the ensemble of ECMWF and CMCC seasonal forecasts systems contributing to C3S
Final version of the software running operationally for the demonstration
Authors: Ripolles Luis
Published: September 2023

This report includes the description and the manuals (both at User and Administrator level) for the OSPAC service and its applications
The first family of application-specific integrated circuits for programmable and reconfigurable metasurfaces
Authors: Petrou Loukas , Kossifos Kypros M. , Antoniades Marco , Georgiou Julius
Published: September 2023

Reconfigurable metasurfaces are man-made surfaces, which consist of sub-wavelength periodic elements-meta-atoms-that can be reconfigured to manipulate incoming electromagnetic waves. However, reconfigurable metasurfaces developed to-date, have limitations in terms of loading impedance range, reconfiguration delay and power consumption. Also, these systems are costly and they require bulky electronics and complex control circuits, which makes them unattractive for commercial use. Here, we report the first family of CMOS application-specific integrated circuits that enable microsecond and microwatt reconfiguration of complex impedances at microwave frequencies. Our approach utilizes asynchronous digital control circuitry with chip-to-chip communication capabilities, allowing simple and fast reconfiguration via digital devices and user-friendly software. Our solution is low-cost and can cover arbitrary board-to-board metasurfaces, with different sizes and shapes.
Material Innovations: Transparent, lightweight, malleable & responsive
Authors: Klassen Filiz
Published: September 2023

This paper  will comment on the issue of weightlessness in architecture and design and the importance of new material research through a brief examination of transportable buildings and building components. In the instances where the act of portability becomes a form-generator, In architecture and design, a different approach to available technology and material resources is required. The author will demonstrate, through designed examples that research on new materials and construction methods will continue to play an important role in the development of innovative design applications for transportable environments.
Convergence of Architectural, Visual and Climate Data
Authors: Klassen Filiz
Published: September 2023

The relationship between buildings and image, both static and moving, has occupied a significant role throughout architectural history. Current innovations in materials research, digital technology and lighting are strengthening this connection as a vital idea permeating image arts and built spaces. The objective of this paper is to expand the intersection of architecture and image within the context of climate change. As the recent kinetic art and media facades as well as the author’s own prototypes highlight, this emergent practice promotes climate conscious interactive systems and sustainable illumination that are integrated into building surfaces. While responding to changes in environmental variables and illuminating the building with renewable energy sources, this alternative approach also emphasizes developing a social and environmental narrative for the use of media facades, challenging the current application for mainly commercial advertising. The author’s own climate responsive prototypes reveal the methodological experimentation with weather elements of snow, rain, light and wind. The three-tiered display of collected climactic information lead to integration of various technologies to make the elements visible, harvest and generate energy from their kinetic movement. This paper will present conclusions drawn from the previous experimentation, as well as a new direction to eliminate additional light pollution while integrating architectural and climate visualization with the sustainable media façade technology in built environments. 
Matter, Material and Making: Creative Research Practice in Architecture and Design
Authors: Klassen Filiz
Published: September 2023

My research/creative projects and teaching provide me with a ‘laboratory of ideas’ for dealing with current challenges as well as imagining the future of built environments within the context of climate change. As Richard Florida (2002) describes in his book ‘The Rise of the Creative Class’, we are in ‘an age of pervasive creativity that permeates all sectors of the economy and society’ (p.56)). I believe that within this context where boundaries between art, science and design dissolve, as artists/ researchers/ academics/ designers/ and makers we can transform the stuff of our imagination to works that matter within larger cultural/ social/ economic/ and environmental contexts. 
Early Experiences in Broadening the Use of Web-Based Learning to Mainstream Faculty
Authors: Brimley William , Rosen Rheta , Freeman Wendy
Published: September 2023

The history of instructional technology is littered with discarded technological innovations that promised to revolutionize the way teaching and learning occurred. This paper will describe the efforts of the staff of the Digital Media Projects Office at Ryerson Polytechnic University in introducing an integrated web-based course delivery package called WebCT to Ryerson faculty and students. The goal was to provide and support a software package that would enable faculty considered to be non-technical to use the web for instruction, extending the reach of this instructional technology beyond that of the typical innovators and early adopters. In this paper we will report on our efforts to ensure that these web-based tools do not ultimately contribute to the list of discarded instructional technologies. Specifically we will reflect on the techniques used to promote and support WebCT, our experiences on the successes to-date and suggestions on how to continue to reach out to faculty not already using web-based tools for instruction
Finding the Individual in Collaborative Online Learning Environments
Authors: Brett Clare , Freeman Wendy
Published: September 2023

Collaborative learning is well suited to online learning environments built around threaded discussion. Research frameworks have developed around these practices providing methodological guidance for examining learning as a collective endeavor within the boundaries of a course. These frameworks may not adequately represent the individual as an active agent within these socially-constructed environments. The aim of this paper is to explore how narrative analysis provides a method for examining expressions of individual identity construction within an online environment. Analysis of a personal story written by a student in her weblog within an online graduate course suggests that individual identity is expressed as the integration of course concepts within practice settings and that the personal discursive space afforded by the weblog supports this integration.
Departamento de Formación y Actualización Académica en sus 12 años de existencia
Authors: Departamento de Formación y Actualización Académica
Published: September 2023

Se presenta una breve reseña sobre el Departamento de Formación y Actualización Académica durante el periodo 2011-2022, teniendo como punto de partida los antecedentes de la formación y actualización docente de los(as) profesores(as) en la Universidad Autónoma de Aguascalientes.
Estetika Garap Tubuh dan Properti dalam Karya Tari Gandhewa Raga
Authors: Wibowo Anggono Kusumo , Samsuri Samsuri
Published: September 2023

ABSTRACTThe dance entitled Gandhewa Raga is a group dance of men and women. This dance is worked on with the beauty of the body and operatives. The body functions as a medium to express the contents of dance and property, as one of the media, said the complement. Disclosure of the beauty of the body worked with property media, namely gandhewa. The motion displayed is the exploration motion of the gandhewa form. The movement of Gandhewa Raga dance is a movement of the Surakarta stout and princess style traditions. This work process aims to explore, find out the meaning of property, and understand the aesthetic values of the body and property. The results of this study are explorations and disclosures of body and property values. The method used is creating dance work with the process of investigation, improvisation, and composition. The aesthetic of the Gendhewa Raga dance will emerge after carrying out the stages of the method. The aesthetic value of body and property can be seen from the form of dance composition that has been arranged and can be enjoyed. This beauty can be enjoyed by aspects of dance movements, namely energy, space, and time, dance accompaniment, fashion make-up, dance performers, staging venues, and property processing. Keyword: Gandhewa Raga, Aesthetic, Phsycal dance, body and property ABSTRAKTari Gandhewa Raga merupakan tari kelompok putra dan putri. Tarian ini merupakan tari yang digarap dengan keindahan tubuh dan poperti. Tubuh yang berfungsi sebagai media untuk mengungkapkan isi tari da propertisebagai salah satu media ungkap pelengkapnya. Pengungkapan keindahan tubuh digarap dengan media propert yaitu Gandhewa. Gerak yang ditampilkan adalah gerak eksplorasi dari bentuk Gandhewa. Gerak karya tari Gandhewa raga adalah gerak tradisi gaya Surakarta gagah dan putri. Proses kekaryaan ini bertujuan untuk bereksplorasi, mengetahui makna properti, dan memahami nilai-nilai estetis tubuh dan property. Hasil penelitian ini merupakan eksplorasi dan pengungkapan nilai tubuh dan properti. Metode yang digunakan adalah metode menciptakan karya tari dengan proses eksplorasi, improvisasi dan komposisi. Estetika ketubuhan tari Gandhewa Raga akan muncul setelah melaksanakan tahapan metode tersebut. Nilai estetis ketubuhan dan propertidapat dlihat dari bentuk koposisi tari yang sudah tersusun dan sapat dinikmati. Penikmatan keindahan tersebut dapat dilihat dengan aspek gerak tari yaitu tenaga, ruang dan waktu, serta iringan tari, tata rias busana, pelaku tari, tempat pementasan dan pengolahan properti Kata kunci: Gandhewa Raga, Estetika, Tari Fisik, Tubuh dan Properti
Pengembangan Sulam Gim Kebaya Pengantin Gaya Surakarta
Authors: Prihatina Yuhri Inang , Guntur Guntur , Rizali Nanang
Published: September 2023

This research was motivated by the existence of gim embroidery as a Surakarta-style bridal kebaya ornament with all limitations, such as the lack of craftsmen, the high cost of yarn materials, and competition with other ornamental techniques that are more developed. The purpose of this study is to describe the development  of  gim  embroidery  on  Surakarta-style  bridal  kebaya.  The  method  used  is  a  qualitative grounded research model. Data were collected through interviews, observations, literature studies, artifact studies, and documentation. Data analysis is conducted interactively through data reduction, presentation, discussion, and conclusions. The results showed that the development of Surakarta-style bridal kebaya gim embroidery had at least three groups, namely the development of materials and techniques that still maintain motifs and patterns according to pakem, the development of motifs and designs that combine the characteristics of Surakarta style and Yogyakarta style, and the development of kebaya forms followed by the development of motifs and patterns. The development that was found can be used as a reference in the development of game embroidery not only in bridal kebayas but also in other forms of revitalization to preserve gim embroidery.Keywords: gim embroidery, Surakarta-style bridal kebaya, development concept.
MULTIPLE EXPOSURE DAN DIGITAL IMAGING SEBAGAI METODE PEMBUATAN PHOTOBOOK BAHASA ISYARAT
Authors: Susanti Kristina Novi , Asran Diana Safinda , Prakoso Priaji Iman
Published: September 2023

This study explores photographic works that can be utilised as fine artwork and as learning media for deaf people. The research method used in creating works of art is searching for ideas, deepening and developing them. Through this method, the creation of photography works bg visualizing hand movement and expressions using two techniques, namely multiple exposure and digital imaging. The object of this photo is someone who has mastered sign language. This research then produced several photographic works combined into a photobook that can be used as a teaching and learning media for teachers and students at special schools.Keywords: photography, sign language, photobook, learning media.
Maximal benefit of minimal residual disease monitoring in pediatric acute myeloid leukemia
Authors: Hasle Henrik , Juul-Dam Kristian Løvvik
Published: September 2023

Not available.
Understanding pharmacological complement inhibition in paroxysmal nocturnal hemoglobinuria
Authors: Risitano Antonio M. , Frieri Camilla
Published: September 2023

Not available.
Innovations in foreign trade management under pre-war neo protectionism conditions
Authors: Boichenko M. V , Boiarkin M. O
Published: September 2023

Methods. To study the risks of neo protectionism for Ukrainian exporters there has been used the following methods: analysis and synthesis, induction and deduction – to identify prerequisites for the formation of neo protectionism in the conditions of globalization. The statistical methods have been used to develop the model of the dependence of the export of products (goods and services) on the indirect methods of neo protectionism to test the hypothesis about the influence of indirect financial support on the stimulation of exports and the creation of new jobs by exporting enterprises. Results. This study offers recommendations for overcoming the risks of foreign economic activity, in particular the relocation of jobs, changes in trade and payment balances on the example of individual countries, as well as the use of discriminatory measures against exporting firms from Ukraine. It is demonstrated that before the war, Ukrainian firms that exported their products and services to foreign markets faced fierce competition for both customers and investments. As most of the world prioritizes trade liberalization, many so-called «developed countries» suffer from the social and political consequences of the global distribution of wealth and labor, which include the movement of jobs abroad and rising unemployment. It was revealed that more and more countries are applying neo-protectionism measures to protect local markets and strengthen the competitive positions of national businesses, so the management of Ukrainian firms should take these risks into account when developing their own foreign trade strategies. Novelty. The article summarizes the arguments and counter-arguments in the framework of the scientific debate on the problem of the revival of neo-protectionism and economic nationalism in the conditions of global economic integration and trade liberalization. Innovative recommendations for minimizing threats to Ukrainian exporting firms from the policy of neo-protectionism in the foreign markets of unfriendly countries in the post-war period are proposed. Practical value. The recommendations provide for reorientation from the markets of unfriendly countries with high non-commercial risks to the markets of partner countries and insurance of commercial risks under the contract using the mechanisms of Public JSC «Export Credit Agency of Ukraine» in the post-war period. The results of the research can be useful for Ukrainian exporting firms and government bodies that regulate the foreign economic activity of trade agents that export dual-use goods.
Ways of improving the efficiency of risk management in the context of integrated risk assessment of electricity industry enterprises
Authors: Savchenko M. V , Vyshnevskyi V. Yu
Published: September 2023

Methods. The theoretical and methodological basis of the research is the work of domestic and foreign scientists. The results were obtained due to the application of a system of methods: the method of logical analysis made it possible to develop the logic of the research; deductions – to identify individual factors affecting the risk level of the enterprise; generalization and synthesis – for the formation of a scientific approach to the integral risk assessment of electric power enterprises. The graphic method made it possible to visualize the obtained research results. Results. Domestic enterprises need the formation of approaches to risk management, which will allow them to ensure proper development and competitiveness. The article substantiates various approaches to risk grouping for electric power enterprises. The most important risks, according to the representatives of the electric power sector, are defined, among which the main ones are regulatory, operational and market risks. The authors prove that market risks in the electric power industry have a specific nature and are inherent only to national markets where there are competitive electricity trades. An approach to the integrated risk assessment of an electric power company has been developed, which is based on: calculation of financial and economic indicators of the company's activity; comparing them with normative values, assigning point values to the calculated coefficients; calculation of intra-group point values of coefficients of the financial and economic condition and calculation of the integral risk indicator of the enterprise's activity. Approbation of the scientific and methodical approach was carried out for the Khmelnytskyi electric power company and it was identified by the level of risk. Novelty. There is substantiated the scientific and methodological approach to the integrated risk assessment of enterprises as a tool for increasing the efficiency of risk management of enterprises in the electric power industry. Practical value consists in the possibility of applying the developed scientific and methodical approach to the integrated assessment of risk by enterprises of various industries. The obtained results allow domestic enterprises to participate in risk management processes and at the same time ensure competitive advantages in the relevant markets.
Association between Serum C-peptide Level and Diabetic Nephropathy in Type 2 Diabetes Mellitus Patients on Oral Anti-diabetic Drug
Authors: Das Adhir Kumar , Tasnim Rumana , Islam Jahidul
Published: September 2023

Background: Diabetic Nephropathy (DN) treatment focuses mostly on preventing or delaying disease development. The most recent research indicates that C-peptide may have a favourable biological effect on DN. In type 2 Diabetes Mellitus, the link between C-peptide level and DN is poorly understood (DM). The purpose of this study is to evaluate the relation between serum C-peptide and diabetic nephropathy in type 2 DM patients taking an oral anti diabetic medication.
Methods: From July 2019 to June 2020, a cross-sectional observational study was done at the Department of Pharmacology and Therapeutics at Dhaka Medical College, Dhaka. A total of 63 randomly selected type 2 diabetes patients met the inclusion criteria. SPSS was used to collect, record, and evaluate biochemical values including FBG, 2hrs ABF, HbA1c, urine for microalbumin, serum creatinine, and serum C-peptide.
Result: Among 63 study participants, 40 (63.5%) were female and 23 (36.5%) were male. Mean age of patients was 50.30±10.55 years. Mean duration of DM of total study subjects was 6.29±3.15 years. Out of total study subjects, 17.5% (11) had low serum C-peptide, 74.6% (47) had normal serum C-peptide and 7.9% (5) had high serum C-peptide level. Correlations of clinical and biochemical variables showed negative correlation between serum C-peptide level and microalbumin, DM duration, FBS, 2hrs ABF, HbA1c, creatinine. Mean urine albumin was higher in patients with low serum C-peptide level. The microalbumin level and the duration of DM of study subjects are significantly associated with serum C-peptide.
Conclusion: In this study we have found that type 2 diabetic individuals with low serum C-peptide levels have a high frequency of diabetic nephropathy and that serum C-peptide levels are significantly associated with diabetic nephropathy.
Bangladesh Journal of Medical Science Vol. 22 No. 04 October’23 Page : 768-772
Melatonin enhances ovarian response in infertile women with polycystic ovary syndrome: A randomized controlled trial.
Authors: Akter Sumaiya , Banu Jesmine , Ishrat Shakeela , Rani Chalontika , Jahan Shirin , Nazneen Sohely , Jahan Nishat
Published: September 2023

Background: Polycystic ovary syndrome (PCOS) is a common endocrine disorder in women of reproductive age. Anovulation, decreased Oocyte quality and low endometrial receptivity are the cause of infertility in women with PCOS. Anovulation is the consequence of hyperandrogenism, insulin resistance. Furthermore, the reactive oxygen species (ROS) induce oxidative stress which may be responsible for poor Oocyte quality. Melatonin is a documented powerful free radical scavenger and broad-spectrum antioxidant. Current evidence suggests that melatonin involves in ovarian physiology including follicular development, ovulation, and oocyte maturation. Present study was tried to evaluate the effects of melatonin on biochemical parameters as well as outcomes of ovulation induction by letrozole in infertile women with polycystic ovary syndrome.
Method: This is a randomized controlled trial including 74 women of Polycystic Ovary Syndrome (PCOS) with infertility. Intervention group received melatonin 3 mg at bed time for 8 weeks as pretreatment. Serum luteinizing hormone (LH), testosterone, anti mullerian hormone (AMH), fasting insulin, oral glucose tolerance test (OGTT) were measured at baseline and after 8 weeks. Both intervention and controlled group were received ovulation induction for 3 cycles by Letrozole (5 mg from cycle days 2 to 6). Intervention group continued melatonin until mature follicle achieved. The primary outcomes were biochemical changes by serum luteinizing hormone (LH), testosterone, anti mullerian hormone (AMH), fasting insulin, oral glucose tolerance test (OGTT) and ovarian responses by number of mature follicles, endometrial thickness and ovulation rate. Secondary outcome was pregnancy rate.
Result: Melatonin treatment for 8 weeks significantly decreased testosterone (P <0.01) serum luteinizing hormone (<P.001), HOMA IR (P<0.01) and glucose tolerance (P<0.01). The change of anti mullerian hormone was not significant (>0.05). There was significant difference in number of mature follicles (< 0.01), mean endometrial thickness (P<0.01). The risk ratio (RR) of ovulation rate was 1.34(0.09-1.68) and pregnancy rate was 2.55 (.37-3.51). The risk ratio (RR) of pregnancy rate in relation to AMH level was 1.12(0.05-1.79) in ≤8ng/ ml group and 8.65(0.25-9.59) in ≥8ng/ml group which was significant.
Conclusion: After 8 weeks pretreatment and 3 cycle’s co treatment with ovulation induction by letrozole, melatonin seems to provide improved biochemical and ovarian response. Based on these results, melatonin could be considered as a potential therapeutic agent for infertile women with polycystic ovary syndrome.
Bangladesh Journal of Medical Science Vol. 22 No. 04 October’23 Page : 850-858
Quality of life change seen after Diverted Mini Gastric Bypass Surgery in Obese Population: Retrospective research analysis
Authors: Singh Arya , Narwaria Mahendra , Patel Prachi , Sinha Susmita , Ahmad Rahnuma , Haque Md Mainul , Kumar Santosh , Sanghani Nandita
Published: September 2023

Background: With an increase in life expectancy all over the globe, morbid obesity and obesity-related diseases negatively impact the overall quality of life (QoL).

Aim: The study aimed to assess the QoL post-Diverted Mini Gastric Bypass (dMGB), focusing on weight loss achieved, comorbidity resolution, and change in QoL after the surgery. Setting: Single private institute, India

Methods : Data from patients who underwent a laparoscopic primary dMGB from August 2020 to August 2021 by one surgeon were retrospectively analyzed. The patients were followed up at 3,6,9, and 12 months from the surgery date. Data were assessed using the Bariatric Analysis and Reporting Outcome System- II (BAROS- II) form based on three major areas: percentage weight loss, comorbidity resolution, and QoL. The variation in QoL was assessed using the Moorehead Ardelt QoL questionnaire, which addresses self-esteem, physical activity, social gathering, and sexual life.

Results: Forty-one patients were included in the final analysis. The average age and pre-operative body mass index (BMI) was 45.5 yrs. and 44.5 kg/m2, respectively. The cohort had 60.9% of males and 39.1% females. The pre-operative average total QoL score was 0.65 ± 0.2. At 12 months, the average BMI and average total QoL were 28.03 kg/m2 and 5.35 ± 0.3, respectively, p<0.001.

Conclusion: At one year, the dMGB surgery effectively improves the overall QoL.

Bangladesh Journal of Medical Science Vol. 22 No. 04 October’23 Page : 759-767
Diverted Mini Gastric Bypass Surgery in Obese Population: Out-turn Over Hepatic and Nephrological Parameters
Authors: Singh Arya , Ahmad Rahnuma , Sinha Susmita , Sinha Susmita , Haq Md Ahsanul , Narwaria Mahendra , Haque Mainul , Kumar Santosh , Sanghani Nandita
Published: September 2023

Introduction: Bariatric surgery is the best possible option for reducing weight when lifestyle changes and medication have not brought about lasting success and may reduce morbidity and mortality. Weight loss that may follow bariatric surgery in patients on calory restricted diet would result in reduced inflammation and therefore lowering inflammation-related organ damage, including that of the kidney and liver. The study aimed to observe the consequences of BMI change on Hepatic and Nephrological parameters in patients after One Anastomosis Gastric Bypass surgery. Method: This study was done at a bariatric center with 150 individuals (both male and female) aged 20 to 60 years with obesity grades II and III who were selected randomly. Hepatic and renal function tests were carried out at baseline visit, then 3 months and 6 months following surgically. Result: Bilirubin level significantly increased from baseline to visit 1; Serum glutamic-pyruvic transaminase (SGPT) levels significantly decreased at visits 1 and 2. The albumin to Globulin ratio was significantly increased at visit 2 . Blood Urea level and serum creatinine level reduced considerably at visit 1 and decreased more at visit 2 from baseline. Conclusion: Bariatric surgery may be related to improvement in both hepatic and renal function. The improvement may be attributed to reduced inflammatory organ damage related to obesity. More such studies must be performed to highlight the possible health benefits of bariatric surgery for obese patients whose lifestyle modification and medication have not aided in weight loss.

Bangladesh Journal of Medical Science Vol. 22 No. 04 October’23 Page : 743-758
Strategy for the Implementation of Health Protocols on Mass Circumcision during a Pandemic in East Jakarta, Indonesia
Authors: Supartono Basuki , Utari Dyah , Kusumaningsih Prita , Kaurow Sarah Primadani , Zahra Dewi Fatimah
Published: September 2023

Background: Circumcision, a religious obligation for Male Muslims in Indonesia, is conducted at a high cost using health facilities. Meanwhile, while wanting to circumcise their children the pandemic situation reduces the economic capacity of the people. Therefore, it is necessary to conduct community service activities in the form of free circumcision performed en masse to help the poor. However, due to the coronavirus pandemic which has spread rapidly since the beginning of 2020, it is necessary to adhere to health protocols. Mass circumcision during a pandemic requires a health protocol strategy to ensure that activities are performed in a safe, comfortable, and satisfying state. East Jakarta has 2,937,859 people, with 486,110 people being children of age 0-19 years. The majority of residents in this city, about 96%, are Muslims. Meanwhile 3% percent of them, or 91,610 people, are considered poor. There is still a high need for the people of East Jakarta to conduct circumcision for their children during the pandemic, even though there is a decrease in their income.

Methods: A free, safe, and comfortable mass circumcision is required with the implementation of health protocols. Out of 170 participants registered for the circumcision, 163 of them passed the Covid-19 screening, while two did not fulfill the indications for circumcision; hence only 161 children were circumcised using the smart clamp. Furthermore, the youngest, oldest, and most circumcised participants were 1, 15, and 5 – 9 years old (60 %), respectively.

Results: The commonly used smart clamps were 13 in numbers, and the average circumcision time for each participant was 6 minutes. Furthermore, there were mild complications among 7 participants (4%). The participants’ parents were satisfied and advised their relatives to partake in mass circumcision in the future.

Conclusion: Meanwhile, there were no reports of participants, parents, health workers, and committee members being infected with the coronavirus after completing the activity. The health protocol implementation strategy was successfully conducted during the free mass circumcision in East Jakarta, which took place safely, comfortably, and satisfactorily.

Bangladesh Journal of Medical Science Vol. 22 No. 04 October’23 Page : 785-796
Pelatihan Pembuatan Cookies Kopi untuk Meningkatkan Potensi Olahan Kopi dan Mengembangkan Keterampilan Anggota PKK Desa Taji, Kecamatan Jabung, Kabupaten Malang
Authors: Zahro Istiq Laily , Latifa Della Dianti , Alam Indra Nur , Rosania Sephina Putri
Published: September 2023

Potensi alam Desa Taji menjadi daya tarik bagi masyakat untuk mendatangi desa ini, baik sekedar untuk berwisata atau menetap untuk melakukan kegiatan ekonomi. Sumber daya alam yang melimpah, kesuburan tanah yang dapat dimanfaatkan untuk sektor pertanian contohnya kebun kopi dan apel, namun keterbatasan pengetahuan dan ketrampilan membuat pengembangan dan pemanfaatan potensi tidak berkembang dengan pesat, sehingga perlu dilakukan penyuluhan dan pelatihan untuk meningkatkan pengetahuan dan ketrampilan anggota PKK dalam pemanfaatan kopi yang bagus dan melimpah menjadi produk cookies kopi. Cookies kopi diuji secara sensoris oleh peserta dan uji kimiawi. Kedua uji menunjukkan cookies kopi memenuhi standar SNI cookies 1992 2973. Hasil Uji sensoris rasa cookies enak, penampilan menarik, bertekstur padat, dan disukai oleh 13 orang dari 16 orang panelis.
Kegiatan Pemanfaatan Tanaman Herbal sebagai Penangkal Covid-19 pada Ibu-ibu PKK Kelurahan Dinoyo
Authors: Kholil A Yusuf , Mutiara Farah , Astuti Farida Kusuma
Published: September 2023

Dunia saat ini sedang dilanda suatu wabah  berbahaya yang baru ditemukan berjenis Covid 19 atau yang biasa dikenal virus corona. Virus ini pertama kali ditemukan di Wuhan, Tiongkok, pada bulan Desember 2019. Hingga saat ini Covid 19   telah menjadi  sebuah pandemi yang mewabah diseluruh belahan dunia, termasuk di Negara Indonesia.Tujuan kegiatan pengabdian masyarakat adalah Sosialisasi ke warga mengenai jenis tanaman herbal (jeruk) dan manfaat yang dapat digunakan untuk menangkal virus dengan metode pendekatan kelompok Sosialisasi cara budidaya dan perawatan tanaman herbal (jeruk) yang tepat, Memberikan bibit tanaman jeruk kepada warga.  Metode kegiatan pengabdian  masyarakat  adalah  dengan  melakukan  penyuluhan pertanian. Metode penyuluhan pertanian dibedakan berdasar 3 jenis, yaitu pendekatan perorangan, pendekatan kelompok, dan pendetan massal.Target yang dicapai dari kegiatan ini adalah 75% dimana Ibu-ibu PKK sudah dapat melakukan budidaya tanaman jeruk sebagai tanaman herbal penangkal Covid-19. selanjutnya target 25% adalah kegiatan pendampingan secara kontinyu
Pelatihan Dokter Cilik “Sadar PHBS” di SDN Ellak Laok IV, Kabupaten Sumenep
Authors: Oktavianisya Nelyta , Aliftitah Sugesti
Published: September 2023

Perilaku hidup bersih dan sehat (PHBS) di sekolah merupakan upaya preventif untuk mencegah terjadinya penyakit yang bisa diterapkan di sekolah, sehingga dapat memberikan motivasi kepada siswa dalam menjaga dan meningkatkan kesehtan, mencegah penyakit, dan meminimalisisr perilaku berisiko. Permasalahan yang ada di SDN Ellak Laok IV adalah siswa tidak tahu cara mencuci tangan dengan benar, masih banyak siswa yang jajan sembarangan, tidak aktifnya Unit Kesehatan Siswa (UKS). Solusi dari maslah tersebut adalah diadakannya pelatihan dokter cilik “sadar PHBS” di SDN Ellak Laok IV. Metode PKM ini adalah sosialisasi untuk meningkatkan pengetahuan siswa tentang PHBS, kemudian dilakukan pelatihan siswa dengan membentuk tim sadar PHBS yang dijuluki dokter cilik dengan dibekali buku pintar PHBS. Buku pintar tersebut berisi penerapan PHBS di sekolah dalam bentuk gambar, sehingga bisa dipahami oleh semua siswa. Kegiatan PKM dilaksanakan di SDN Ellak Laok IV Kecamatan Lenteng pada bulan Juli 2019-Januari 2020. Hasil kegiatan pelatihan dokter cilik “sadar PHBS” ini berdampak baik yaitu hampir seluruhnya siswa pemahamananya meningkat dan penerapan PHBS masuk kategori baik.
Peran PGPR sebagai Bahan Ramah Lingkungan dalam kegiatan Pemberdayaan Kelompok Tani di Desa Pujon Kidul
Authors: Suryanto Agus , Sudiarso Sudiarso , Permanasari Paramyta Nila , Fajarwati Santi Kusuma , Damaiyanti Dewi Ratih Rizki
Published: September 2023

Desa Pujon Kidul merupakan desa pertanian yang memiliki luas lahan pertanian sayur mencapai 2.513 hektar dan 0.3 hektar digunakan budidaya tanaman padi dengan ketinggian wilayah 1200 m. Penggunaan PGPR dan pupuk organik yang merupakan bahan ramah lingkungan oleh petani Desa Pujon Kidul masih sangat terbatas sehingga berpengaruh terhadap kesehatan masyarakat dan kualitas lingkungan. Kegiatan pengabdian masyarakat dilakukan oleh KJF Sumber Daya Lingkungan yang bertujuan untuk meningkatkan pemahaman kelompok tani terhadap aplikasi PGPR dalam kegiatan budidaya tanaman pangan. Metode yang digunakan yaitu dengan penyuluhan aplikasi PGPR kepada masyarakat Desa Pujon Kidul khususnya kelompok Tani Sari Agung dan pembuatan demplot. Luaran yang diharapkan yaitu 1) Pemahaman kelompok tani Sari Agung terhadap aplikasi PGPR tanaman cabai, dan 2) Pemahaman tentang teknologi budidaya tanaman cabai yang sehat. Kesimpulan dari kegiatan ini yaitu penyuluhan dan praktek penggunaan PGPR pada budidaya tanaman cabai membuka wawasan petani di Desa Pujon Kidul untuk menggunakan bahan ramah lingkungan, hal ini diperoleh dari kegiatan FGD (Forum group Discussion) dan data diperoleh melalui kuesioner. Rencana pengabdian kepada masyarakat selanjutnya dengan memberikan pendampingan pembuatan kebun bibit melalui metode pengomposan dan PGPR di Desa Pujon Kidul. Saran pelaksanaan kegiatan pengabdian kepada masyarakat yaitu perlu integrasi pengendalian hama pathogen terpadu pada budidaya tanaman cabai.