bluuebunny/crossref_metadata_2025 huggingface dataset:
Dying by the sword: Manliness, honour, and duelling on and off the stage, 1695-1745
Authors: MacNeill Máire
Published: March 2020

How ought a gentleman in the early eighteenth century to behave?  This question confounded contemporary writers in search of an ideologically pure version of manliness, and it is this that I will use as a starting point for my presentation.  I will briefly discuss the stereotypical figure of manliness during the Restoration period—the rake, who drank, gambled, whored, and duelled—and how he exhibited traits that writers no longer wanted to encourage; however, the popular association with this figure and manliness remained.  I will go on to argue that a hero who avoided the traditional manly activities that the rake enjoyed ran the risk of falling into the effeminate stereotypes of the fop.  Ideal manly qualities had to be reconfigured in such a way that they did not become undesirable.
19/87
Authors: Pariat Janice
Published: March 2020

In 1987, Shillong, the small hill-station town that I come from in the far northeast of India, played backdrop to swift and violent ‘ethnic’ conflicts between the local Khasis and ‘dkhars’ (the Khasi word for ‘outsider’). The designation ‘dkhar’ implies the drawing of borders of purity in terms of bloodline and lineage. This fiction piece is about the relationship between two unlikely friends – Suleiman, a Muslim tailor fond of flying kites and Banri, a Khasi youth with a penchant for betting. The story gives voice to alternative conceptions of belonging and being indigenous to a place, and to the peripheral expressions of the awkwardness of purity.
The Jest of the (In)Finite: Cataloguing the Clôtural Boundaries of Logocentric Totality in David Foster Wallace’s Infinite Jest
Authors: Tucker William Shane
Published: March 2020

The late David Foster Wallace’s magnum opus, Infinite Jest (1996), is an eclectic and expansive encyclopedic novel totaling nearly 1,100-pages in length, which simultaneously adopts and challenges the encyclopedic convention of logocentric boundaries assumed by Wallace’s encyclopedic precursors. The work attempts to marginalise the boundaries that separates informational totality—the known, expressible data capable of being recorded—from that which is unknown and/or inexpressible: the infinite. While it is impossible to completely transverse these boundaries, Wallace also refuses for his work to be completely subservient to the boundaries of totality. This struggle is the epitome of Emmanuel Levinas’ call in Totality and Infinity for opening the Self up to his notion of the infinite Other—an Other that cannot be conceptualised within a system of logocentric totality. Despite the problematic nature of resting on such a foundation (or lack thereof), it will be argued that through the concept of the clôture Wallace's novel indeed rests on such a liminal ground that maintains as well as fractures the interior/exterior dialectic delineating the boundaries between totality and infinity—and by extension—selfhood and Otherness.
Boundaries Unbound: Jude, Adaptation and Assemblages
Authors: Morris Nigel
Published: March 2020

Most commercial films are hybrid, at the boundaries of two or more genres. Literary adaptations, furthermore, seemingly straddle two media and their study crosses disciplines. Analysis here of Jude (Winterbottom, 1996) examines paratextual and peritextual features to account for its emergence and subsequent fortunes. These involve not only directorial vision, conscious conflation of filmmaking styles, and ‘fidelity’ or otherwise to its ‘source’, but conjunction of particular taste formations, conflicting commercial strategies, contrasting audiences and modes of address, and yoking together of institutional models, each with its distinctive ethos, of financing, production, and distribution. Like any text, Jude is a contingent product of time and place. Its disappointing takings, despite critical praise and enduring admiration, are, this paper contends, explained by its positioning at the boundary of two markets; months earlier this would have been refreshing and radical, but in the brief period between conception and release its commercial context altered irrevocably.
How not to Occupy Bartleby
Authors: Sequeira Bras Patricia
Published: March 2020

This article aims to discuss how Bartleby, the character from Herman Melville’s homonymous story, Bartleby, The Scrivener re-emerged in the Occupy Movement in Wall Street. Here, I intend to argue that Bartleby has been wrongly appropriated, which in turn, may explain the shortcomings of the movement. The Occupy Wall Street took possession of Bartleby because in Melville’s story, he occupies the premises of a lawyer’s office in Wall Street. However, this appropriation has dismissed the political 'inefficacy' of Bartleby’s formula, 'I would prefer not to'. As I shall argue, the formula exposes instead a residual political emancipation, generating a contingency. Rather than attempting to find some political agency within Melville’s figure, we should recognise the capacity of his formula for political insurgency. With this perspective in mind, I shall revise this appropriation to suggest that despite the political contingency of Bartleby’s formula, this should not be regarded as a means to a political outcome.
Howling for Justice: New Perspectives on Leslie Marmon Silko’s Almanac of the Dead by Rebecca Tillett (ed.)
Authors: Ward Kiron
Published: March 2020

Review of Howling for Justice: New Perspectives on Leslie Marmon Silko’s Almanac of the Dead by Rebecca Tillett (ed.)
The Antinomies of Realism by Frederic Jameson
Authors: Harding Rebecca Angharad
Published: March 2020

Rebecca Harding reviews Frederic Jameson's latest publication, The Antinomies of Realism.
Playing the Whore by Melissa Gira Grant
Authors: Oliver Jessica
Published: March 2020

Melissa Gira Grant’s latest book examines the denial of basic labour rights for sex workers, and the external factors behind this, including the attitudes of the police, media and politicians. The book is a sharp critique of the sensationalist treatment of the industry and behaviors of establishment figures that proves timely in the wake of Amnesty’s recently declared support for global decriminalization.
Preface
Authors: Gurowich Tim , Harding Rebecca
Published: March 2020

Preface to Failure
Drifting Peasant Workers: The Reflection of the Hukou System within the Chinese Cinematic Network
Authors: Deng Huimin
Published: March 2020

Migrating from rural areas to urban areas, Chinese farmers become part of the urban working class. The migration have attracted both urban cinema and independent documentary to represent the integration of farmers into urban space. However, whether the figures of peasant workers in urban areas can be simply treated as the urban working class is problematic. Here I introduce the theories of textuality and intertextuality to explore the audiovisual representation of Chinese migrant workers within Chinese urban cinema and Chinese independent documentary at the turn of the 21st century, searching for the communal sign representation and social signification of peasant images within urban context. As a result, peasant workers are depicted as drifters between urban areas and rural areas because they are marginalized by local workers, urban elites, and urban governors due to the household registration system. Their identity, cultural manifestation, and social status are shaped by the rural-urban mediation, if not conflict.
Men are Vulnerable too: Analysing the Self-presentation of Indian Men’s Right Activist Online Networks
Authors: Tonini Maria
Published: March 2020

In this article, I examine the content of online pages of Men’s Rights Activists (hereafter MRAs) in India. The objective of my analysis is to illuminate what discursive elements are used by Indian MRA groups to motivate their existence and their mission. My primary sources are texts posted on websites and Facebooks pages. The argument I put forward in this paper is that Indian MRAs justify their mission by manipulating and re-articulating the meaning of ‘gender’ so that it becomes a useful category only when attached to men. While MRA groups are present and active in several countries worldwide, I argue that the Indian case is particularly illuminating when it comes to shedding light on the growth of anti-feminist communities at a time when “masculinist political revival” (Maellström 2016) is on the rise globally.
To be real for you: acousmatic cyborgs, asexuality, and becoming human
Authors: Barr Ashley
Published: March 2020

Figured as either subhuman, superhuman, or too nearly human, cyborgs in cinema are often used as a vehicle for expressing anxieties about the instability of “real” humanity as a position. Their representations in film reveal the broader cultural logics that are used to define humanity. These logics often rely on demonstrating social and emotional learning that centers the experience of (especially hetero)sexual attraction and desire, which is opposed to mechanical rationality, coded as “asexual,” so that sexuality is taken to be foundational to the concept of humanity. In this paper I will elaborate on the cultural logics behind humanity’s affiliation with sexuality, especially as they are manifested in the narrative structures of the films Blade Runner 2049 (2017) and Her (2013). These two films are of particular interest because their artificially intelligent cyborg characters directly express the desire “to be real for” the benefit of a comparatively more “real” protagonist — and this desire is mediated through heterosexuality. I will argue that the threats that cyborg pose to our sense of humanity, and attempts to address these threats in film, ultimately reveal the concepts of sexuality and sexual attraction, as well as humanity along with them, as mechanical effects rather than innately possessed characteristics. If becoming really human depends on normalization through sexuality, then the positioning of asexuality at the boundaries of humanity is an instructive starting point for reconceiving the positive values associated with achieving humanity. Instead of attempting to normalize the threat to our being that is represented by the kind of lives that refuse to cohere with established concepts of real humanity, we must engage with the experience of the threat and its suggestion that those things that make us “real” are not, in fact, very human after all.
Gender Precarity: Gender Identity and the Economy of Authenticity
Authors: Carpenter Benjamin
Published: March 2020

In this paper I examine the role of authenticity within contemporary debates about gender identity with an eye to exploring the structure of sex and gender-based oppressions - with particular consideration with the marginalisation of trans subjects. I begin with a return to Butler's Gender Trouble to critically examine her ontology of gender and the suggestion that gender cannot be a matter of authenticity. Though this disagrees with the common schematic of trans identity mobilised within contemporary identity politics, this paper seeks to use this critique to provide a deeper explanation of trans oppression within the context of Butler's heterosexual matrix. The aim of this move is to situate trans struggles as central within philosophical feminist theory - whilst breaking from several of the shortcomings of contemporary identity ontology. These considerations will then be explored alongside Butler's work in Precarious Life, wherein the oppression of trans people will be explored in how these subjects bear a greater burden of authenticity - wherein trans genders are automatically regarded as authentic whereas cis genders remain unquestioned. This contextualises the rhetorical and ontological move adopted by many trans activists whereby they present gender as a matter of absolute and inviolable fact - which is incompatible with Butler's ontology of gender. Using bother of Butler's texts, we can regard this move as the pursuit of an impossible security, a move that serves to obscure the inauthenticity of gender overall. Instead, we are encouraged to embrace in inauthenticity of gender and to refuse to allow ourselves to sink into an economy of authenticity that marginalises trans subjects.
A look into the picture-perfect fake life of Amalia Ulman’s Excellences and Perfections
Authors: Salazar Manuela
Published: March 2020

In 2014, the Spanish artist Amalia Ulman gathered inspiration from the ways of aestheticizing everyday life chosen by Instagram users to develop an elaborate performative photographic series that lasted months and existed firstly only on her personal Instagram feed @amaliaulman. In April of that year, she suddenly started posting iPhone photographs about an apparently trendy life she was living in Los Angeles, California. She started reproducing the style of different Instagram personas while incorporating the usual aesthetic choices of the social media. The narrative constructed by each of the 175 pictures accounted for her life as an artsy girl who firstly moves to LA after apparently breaking up with a boyfriend, starting work as an escort, having cosmetic plastic surgery and drug abuse issues, followed by time in rehab, and finally posts about recovery, and healthy and fitness habits. The attention to the details of what she wrote and exhibited was what probably made the almost 90 thousand subscribers she gathered along the 5 months of the performance very surprised when she finally announced it was all part of an art work entitled Excellences and Perfections. This fictional life of Amalia Ulman was thoroughly calculated to appear believable to an audience already accustomed to aesthetics of this social media visual culture by reproducing certain patterns of pictures, captions, use of hashtags and interactions with followers. This paper will analyse the performance via the Instagram archive as well as the recently published book Excellences and Perfections. (2018), discussing the ways that it deals aesthetically with questions of identity, gender, class, sexuality and “lifestyle porn” in a visual network platform. The main question to be discussed is: how did the aesthetic choices of this performance made a fake story so convincing?
Luxury for the Many: Politics and Virtues of the Knockoff
Authors: Bombardini Silvia
Published: March 2020

The object and subject of this paper is the luxury knockoff. Cheap, primitive, fragile and shiny, the fake’s omnipresence makes luxury logos common, it instils doubt at the sight of what was designed as undeniable proof of wealth. Though theirs depends on the existence of exclusive desirables, the analysis shows by way of examples how different types of counterfeits – such as Yuandan goods – come to question the nature and notion of luxury. It examines fakes in their materiality: textiles and labels, the language of misspelt brand names that Lin and Tatarsky read “as a subversion … of Western cultural imperialism”. It then considers their reproduction, tracing back the spillage and trajectories of counterfeits’ diffusion from their birthplace – the Pearl River Delta region in China, for the most part – across cultural and physical borders. An argument is made for thinking counterfeits’ consumption through Jean Baudrillard’s notion of hyperconformity: as a “refusal by over acceptance” of neo-colonial consumerism. The aim is to demonstrate that the destabilising potential of fakes does not rely on the motivations and intentions of the humans who produce and consume them, but that objects produced and consumed in response to a culture of extreme materialism may inadvertently become allies in the resistance against global capitalism, and the system of values of Western import that it imposes.
The Clinically Validated Viral Superinfection Therapy (SIT) Platform Technology May Mitigate Severe Cases of COVID-19 Infections
Authors: Kovesdi Imre , Ranst Marc Van , Chumakov Peter M. , Sandig Volker , Bakacs Tibor
Published: March 2020

The transmission characteristic of COVID-19 is of similar magnitude to severe acute respiratory syndrome-related coronavirus (SARS-CoV) and the 1918 pandemic influenza. The virus is now in 50 countries and on nearly all continents. The World Health Organization (WHO) says to prepare for a pandemic. There is no current evidence from random clinical trials (RCTs) to recommend any specific anti-COVID-19 treatment for patients with suspected or confirmed COVID-19 infection. In order to mitigate the impact of the COVID-19 outbreak, here we propose an innovative superinfection therapeutic (SIT) strategy, which could complement the development of prophylactic vaccines. SIT is based on clinical observations that unrelated viruses might interact in co-infected patients. During SIT, the patient benefit from superinfection with an apathogenic dsRNA virus such as the infectious bursal disease virus (IBDV), which is a powerful activator of the interferon-dependent antiviral gene program. An attenuated vaccine strain of IBDV was already successfully administered to resolve acute and persistent infections induced by two completely different viruses, the hepatitis B (DNA) and C (RNA) viruses (HBV/HCV). Importantly, the epidemiological efficacy of a similar strategy to SIT had already been successfully tested in large controlled trials. Standard live orally administered enterovirus vaccines that stimulate the production of endogenous interferon of the host mitigated the seasonal outbreaks of influenza and other associated acute respiratory infections in 152,042 individuals without adverse reactions.
Performance Comparisons of Bio-micro Genetic Algorithms on Robot Locomotion
Authors: Chávez-Estrada Francisco A. , Sandoval-Gutierrez Jacobo , Herrera-Lozada Juan C. , Olguín-Carbajal Mauricio , Martínez-Vázquez Daniel L. , Hernández-Bolaños Miguel , Rivera-Zárate Israel
Published: March 2020

This paper presents a novel micro-segmented genetic algorithm (μsGA) to identify the best solution for the locomotion of a quadruped robot designed on a rectangular ABS plastic platform. We compare our algorithm with three similar algorithms found in the specialized literature: a standard genetic algorithm (GA), a micro-genetic algorithm (μGA), and a micro artificial immune system (μAIS). The quadruped robot prototype guarantees the same conditions for each test. The platform was developed using 3D printing for the structure and can accommodate the mechanisms, sensors, servomechanisms as actuators. It also has an internal battery and a multicore embedded system (mES) to process and control the robot locomotion. This research proposes a μsGA that segments the individual into specific bytes. μGA techniques are applied to each segment to reduce the processing time; the same benefits as the GA are obtained, while the use of a computer and the high computational resources characteristic of the GA are avoided. This is the reason why some research in robot locomotion is limited to simulation. The results show that the performance of μsGA is better than the three other algorithms (GA, μGA and AIS). The processing time was reduced using a mES architecture that enables parallel processing, meaning that the requirements for resources and memory were reduced. This research solves the problem of continuous locomotion of a quadruped robot, and gives a feasible solution with real performance parameters using a μsGA bio-micro algorithm and a mES architecture.
Toward the Modeling of Russia's Monetary System
Authors: Borodachev S.M.
Published: March 2020

The paper gives an explanation of the dynamics of the money masses in Russia through cross-border flows of rubles and (foreign) currency and the creation of deposits by commercial banks. Volumes of flows and deposits in turn depend on changes in the currency/ruble exchange rate. It was found that the growth/fall of the USD rate by 1 RUB for the month, for the same month decreases/increases: currency outflow abroad by 0.111 billion USD and creation of ruble deposits and the inflow of rubles from outside by 0.133 billion USD.
Amino-modified Silica as Effective Support of the Palladium Catalyst of Hydrogenation
Authors: Latypova Adele R. , Lebedev Maxim D. , Rumyantsev Evgeniy V. , Filippov Dmitry V. , Lefedova Olga V. , Bykov Alexey V. , Doluda Valentin Yu.
Published: March 2020

The article describes synthesis of aminoorgano-functionalized silica as a perspective material for catalysis application. The amino groups have electron donor properties valuable for metal chemical state of palladium. So presence of electron donor groups is important for increasing of catalysts stability. The research is devoted to investigation of silica amino-modified support influence on activity and stability of palladium species in 4-nitroaniline hydrogenation process. A series of catalysts with different supports such as SiO2, SiO2-C3H6-NH2 (amino-functionalized silica), γ-Al2O3 and activated carbon were studied. The catalytic activity was studied in the hydrogenation of 4-nitroaniline to 1,4-phenylenediamine. The catalysts were characterized by scanning electron microscopy, transmission electron microscopy, x-ray photoelectron spectroscopy, Fourier transform infrared spectroscopy and pulse chemisorption of hydrogen. The 5 wt. % Pd/SiO2-C3H6-NH2 catalyst exhibited the highest catalytic activity for 4-nitroaniline hydrogenation with 100% conversion and 99% selectivity with respect to 1,4-phenylenediamine.
From Religious Heritage to Cultural Heritage: Study the Heritage of Buddhism in Vietnam
Authors: Hong Van Vu
Published: March 2020

In history and the present, Buddhism holds an important position in the spiritual life of Vietnamese people. For about two thousand years of existence and development with the Vietnamese people, Buddhism has left many valuable (tangible and intangible) heritage, has contributed a significant part in creating the cultural values of the nation. This research focuses on analyzing how did Buddhism creates heritages, how that Buddhism religion heritage becomes the cultural heritage of the Vietnamese people, the values that Buddhism religious heritage contributed to the culture of Vietnam.
Investigation of the Health Effects of Workers Exposed to Respirable Crystalline Silica during Outdoor and Underground Construction Projects in Greece
Authors: Keramydas Dimitrios , Bakakos Petros , Alchanatis Manos , Konstantakopoulos Ioannis , Papalexis Petros , Tavernaraki Kyriaki , Dracopoulos Vasileios , Papadakis Antonios , Pantazi Eugenia , Sidiropoulou Nektaria , Chelidonis Georgios , Chaidoutis Elias , Constantinidis Theodoros C. , Chochlakis Dimosthenis , Kavantzas Nikolaos , Patsouris Efstratios , Lazaris Andreas Ch.
Published: March 2020

Chronic exposure of workers to powder containing crystalline silica (SiO2) can lead to chronic lung diseases (lung cancer, silicosis, etc.). The aim of the study was to evaluate the exposure of Greek construction workers to SiO2 and describe their pulmonary function. The study involved 86 outdoor and underground workers. Medical and professional history was obtained, and samples were collected for the determination of SiO2 levels. Pulmonary function tests, radiological examination and evaluation of radiographs were, also performed. During the examination of the pulmonary function, the majority of the workers were within normal range (61.4%) while the rest were diagnosed with mild (26.5%) and more severe impairment (7.2%). Working conditions (underground-outdoor) were statistically significantly related to the categorization of pulmonary function (P = 0.038). During radiological examination, the type of working conditions (underground-outdoor) were statistically significantly related to the categorization of these findings (P = 0.044). Of the 69 employees, 52 did not present findings (75.4%) and five (5) were diagnosed with findings specific to occupational diseases (7.2%). The environmental exposure to RCS (Respirable crystalline silica) was detected at 12 mg / m3 in the workplace, which is beyond the legal limits. Underground workers with more than 15 years of exposure to SiO2 may experience silicification in its chronic form compared to the workers of outdoor activities.
Embouchure Muscle Activity in Student and Elite Trumpeters
Authors: Watson Alan HD , Price Kevin
Published: March 2020

AIMS: Objective information on embouchure muscle use in brass players is currently limited. This pilot study records and analyses embouchure muscle activity in trumpet players to identify typical patterns and to reveal how these can differ between playing tasks. METHODS: Activity in
four embouchure muscles was recorded using surface electromyography in 7 conservatoire trumpet students and 3 elite professional trumpeters. Each played a set of simple exercises, tongued and slurred, including single notes of different pitch, upward and downward transitions between notes
a fifth apart, arpeggios, and a short musical piece. RESULTS: Muscle activity was initiated 0.4–2.0 s before the beginning of a note. In some players this was at a higher level than needed to sustain the note, while in others it was not. Levels of activity in all muscles generally increased
and decreased together during arpeggios, in line with changing pitch. The sound was terminated by an abrupt fall in muscle activity. In many players, transitions between notes a fifth apart required no change in muscle activity, though in others this was marked by a sharp increase or decrease.
CONCLUSION: Though levels of muscle activity rose consistently over large pitch ranges, there was considerable variation in the degree to which this occurred over smaller intervals. Even among the 3 professional players, the embouchure muscle activity showed clear individual patterns, suggesting
that high levels of performance can be achieved in different ways. Further investigations will be needed to clarify how embouchure activity changes with proficiency.
The menopausal symptoms and depressive symptoms were efficacy of interaction between levels and duration of exercise in perimenopausal women:a cross- sectional study
Authors: Wei Shuang-shuang , Zhang Zhi-fen , Liu Wen-hua , Tang Shan-shan , Huang Jian
Published: March 2020

Background Depressive disorder often adversely affects psychosocial and physical functioning. Exercise is one of the most commonly used alternatives for mood disorders and menopausal symptoms during the menopausal transition. This study aimed to investigate the interaction between levels and duration of exercise and their effects on menopausal symptoms and depressive symptoms. Methods We enrolled 512 healthy women aged 40–60 years. Exercise history, menopausal symptoms (MKS), and depressive symptoms (HAMD) were determined based on self-report. Menopausal symptoms and depressive symptoms was analyzed using a 2-way analysis of variance(ANOVA) with levels of exercise and duration of exercise as factors, respectively. Significant main effects or interactions were examined using Fisher’s Least Significant Difference (LSD) tests. Specific planned comparisons were made using Bonferroni corrections. Results There were interactions between levels and duration of exercise on the change in menopausal symptoms and depressive symptoms, respectively[ F (6,512) = 3.597, F (6,512) = 2.128, p <0.05]. Pairwise comparisons of the interaction revealed that, with moderate duration of exercise, those women who did high level of exercise had lower scores of MKS and HAMD than those who seldom exercised ( P <0.05). Short or long duration of exercise and low or high levels of exercise was not effective at reducing scores of MKS and HAMD( p >0.05). Conclusions The relationship between exercise and menopausal symptoms had a U-shaped trend. The relationship between exercise and depressive symptoms also had a U-shaped trend.
Simple Strategy for Rapid and Sensitive Detection of 2019 novel coronavirus Based on Antibody
Authors: Hu Xinjun , Deng Huiyang , Shang Yibing , Fan Mengnan , Yue Feng
Published: March 2020

Objectives: Since December 2019, acute respiratory disease due to 2019 novel coronavirus emerged in Wuhan city and rapidly spread throughout China. Real-time RT-PCR is widely deployed in diagnostic virology. However, the positive detection rates of RT-PCR are only 30% to 50%. Therefore, we propose a simple strategy for rapidly and sensitively detecting the IgM/IgG antibody against 2019-nCoV using a colloidal gold-based immunochromatographic strip test.Methods A total of 41 clinically 2019-nCoV suspected cases (23 males and 18 females) were enrolled. The sensitivity of colloidal gold-based immunochromatographic strip test and of RT-PCR were compared and evaluated. McNemar’s test was used to compare the detection rate of both assays (P<0.05).Results: The Antibody was detected in 63.4% (26/41) of blood specimens using the assay. In contrast, the 2019-nCoV was detected in 46.3% (19/41) of nasal and pharyngeal swab specimens using the RT-PCR assays. The detection rate obtained by this assay was markedly higher than that obtained by the RT-PCR assays (P=0.039)Conclusion: This detection assay exhibits a higher detection sensitivity than RT-PCR. More important, the assay shows the benefits of easy operation and setup. We believe that the sensitive and time-saving approach may be used as an auxiliary diagnostic tool for 2019-nCoV detection and virus screening and confirmation.
Materialität und digitale Medialität in der erziehungswissenschaftlichen Medienforschung
Authors: Bettinger Patrick
Published: March 2020

Qualitative Sozialforschung steht vor methodischen und methodologischen Herausforderungen, da sich Sozialität im Kontext der Digitalität auf grundlegende Weise wandelt. Der Beitrag schlägt eine Perspektive vor, die sich der ‹medialen Verfasstheit› von Phänomenen widmet und hierbei die komplexen Verschränkungen von Menschen und Medien auf unterschiedlichen Ebenen berücksichtigt. Auf Grundlage einer praxeologisch-diskursanalytisch fundierten Herangehensweise wird gezeigt, wie Medialität und Materialität als aufeinander bezogene und quer zur Unterscheidung von Online- und Offline-Sphäre liegende Analysedimensionen erschlossen und medientheoretisch fruchtbar gemacht werden können, um die Konstitution von sozio-medialen Konstellationen zu erfassen. Die hier vorgeschlagene Herangehensweise wird am Bereich der qualitativen Medienbildungsforschung exemplarisch skizziert. Erste methodische Konkretisierungen werden im Zuge dessen mit Blick auf die Analyse diskursiver Praxis veranschaulicht.
Editorial: Erziehungswissenschaftliche und medienpädagogische Online-Forschung: Herausforderungen und Perspektiven
Authors: Fromme Johannes , Iske Stefan , Leik Therese , Rehfeld Steffi , Bastian Jasmin , Pietraß Manuela , Rummler Klaus
Published: March 2020

Die vorliegende Publikation widmet sich dem Verhältnis von Erziehungswissenschaft, Medienpädagogik und Online-Forschung. Den Ausgangspunkt bildet die aktuelle Frage nach den spezifischen Herausforderungen und Chancen der Prozesse der Mediatisierung und Digitalisierung für Gesellschaft und Individuen aus einer erziehungswissenschaftlichen Perspektive (Knaus, Meister und Narr 2018). In den Fokus gerückt werden dabei veränderte Anforderungen an die empirische wie theoretische erziehungswissenschaftliche Forschung, insbesondere die Online-Forschung. Sie ist nicht allein eine online betriebene Forschung, sondern sie untersucht Online-Medien auch offline und umfasst Methoden, die mit Hilfe von Online-Medien betrieben werden.
Pollen Appearance and In Vitro Germination Varies for Five Strains of Female Hemp Masculinized Using Silver Thiosulfate
Authors: DiMatteo Jessica , Kurtz Lauren , Lubell-Brand Jessica D.
Published: March 2020

Genetically female seed is sought for cannabidiol (CBD) hemp production because CBD is extracted from the flowers of female hemp plants. The production of all female seed requires masculinization of female plants to produce genetically female pollen that reliably generates female seed. Of the five female hemp genotypes that we masculinized using foliar sprays of silver thiosulfate (Abacus, Cherry Wine, Mountain Mango, Youngsim10, Wife), all genotypes produced fewer large and more irregular or misshapen pollen grains than genetically male plants. The masculinized female genotypes Wife and Cherry Wine produced pollen with germination rates similar to those of the male genotype Kentucky Sunshine. Female hemp genotypes vary in their ability to produce usable pollen that disperses well, is easily collected, and germinates as well as pollen from genetically male hemp plants.
Front dynamics in the XY chain after local excitations
Authors: Eisler Viktor , Maislinger Florian
Published: March 2020

We study the time evolution of magnetization and entanglement for
initial states with local excitations, created upon the ferromagnetic
ground state of the XY chain. For excitations corresponding to a single
or two well separated domain walls, the magnetization profile has a
simple hydrodynamic limit, which has a standard interpretation in terms
of quasiparticles. In contrast, for a spin-flip we obtain an
interference term, which has to do with the nonlocality of the
excitation in the fermionic basis. Surprisingly, for the single domain
wall the hydrodynamic limit of the entropy and magnetization profiles
are found to be directly related. Furthermore, the entropy profile is
additive for the double domain wall, whereas in case of the spin-flip
excitation one has a nontrivial behaviour.
Pediatrician’s thoughts about infant feeding
Authors: Panfilova V. N.
Published: March 2020

This article discusses the common nutritional problems of children in their first years of life, leading to nutritional deficiency in infants. A high frequency of micronutrient and vitamin deficiencies in nutrition is observed in both nursing mothers and their children; it can be explained by a lack of awareness of parents about the rules of feeding, the introduction of complementary foods and the fear of introducing solid food to children, especially if they have typical functional gastrointestinal disorders. This problem is solved by the fulfillment of the available clinical feeding recommendations, the rules for the timely and safe introduction of complementary foods using high-quality industrial products to ensure the physiological needs of the child in food ingredients while observing the psychological comfort of the children and their parents.
Scientific critical review of clinical trials: is the objectivity important?
Authors: Blokhin B. M. , Nikiforov V. V.
Published: March 2020

In 2016, a multicenter double-blind placebo-controlled randomized clinical trial in parallel groups was completed in the Russian Federation to evaluate the efficacy of the liquid dosage form of Anaferon for children in the treatment of acute respiratory viral infections in children. The design and main results of the study are presented in the largest foreign database ClinicalTrials. gov of the National Library of Medicine of the USA. In November 2018, the collection of reports of the XIII Russian Scientific  and Practical Conference with international participation “Health is the basis of human potential: problems and solutions” published the article of the Russian chemist N.N. Khromov-Borisov, where the author questions the reliability of the study of the liquid form of Anaferon for children. The presented article analyzes the legitimacy of the author’s claims. From the point of view of statistics, the analysis of N.N. Khromov-Borisov cannot be considered objective and correct, since it contains gross methodological errors.
Pathophysiological aspects of liver damage in children with alpha-1-antitrypsin deficiency
Authors: Volynets G. V. , Nikitin A. V.
Published: March 2020

Alpha-1-antitrypsin deficiency is an autosomal recessive disease characterized by both liver damage and lung disease in children and adults because of a decrease in the serum protein content due to the mutations in the PI (proteinase inhibitor) gene. The majority of liver diseases are associated with a homozygous mutation of the Z allele. There are many variations of clinical manifestations of the liver disease in children with the PI*ZZ genotype.  In the neonatal period, liver disease is usually cholestatic; and it is accompanied by a prolonged cholestatic jaundice, skin itching, which can be determined only later (after 6 months), decreased appetite and bad weight gain, hepato- and splenomegaly. The article describes the pathophysiology of liver damage in children with alpha-1-antitrypsin deficiency. The authors provide their recommendations for the management of children with suspected and confirmed alpha-1-antitrypsin deficiency.
Results of use of seawater spray with brown algae extract in the early postoperative period in children after adenotomy
Authors: Konischev D. V. , Elovikov A. M. , Ivanov A. I. , Shabunin D. V.
Published: March 2020

Adenotomy is one of the most common surgeries on the part of ENT organs in childhood, it is usually performed under endotracheal anesthesia.

Purpose. To evaluate the effectiveness of the spray containing sea water and brown algae extract in the early postoperative period in children after adenotomy.

Characteristics of the children and research methods. 24 patients aged from 4 to 10 years (12 boys and 12 girls) were examined and treated in the Otorhinolaryngology Department of the Perm Regional Children’s Clinical Hospital. All patients underwent adenotomy due to hypertrophy of the pharyngeal tonsil of the II–III degree, they received antibiotics for 5 days after surgery. The patients were divided into 2 groups: Group 1 (study group, n=12) used, Aqualor Protect spray for irrigation therapy of the nasal cavity and nasopharynx; Group 2 (comparison group, n=12) used a spray with isotonic sodium chloride solution for irrigation therapy. 2 doses of saline solution were sprayed into each nostril 4 times for 4 days.

Results. According to the medical examination, the study group demonstrated more pronounced improvement of the following indicators (visual analogue scale scores): overall health (p<0.05), swelling of the nasal cavity (p<0.05), hyperemia of the mucous membrane of the nasal cavity (p<0.05), improved nasal breathing (p<0.034), the presence of mucous-hemorrhagic crusts in the nasal cavity (p<0.0001), general feelings (p<0.02).

Conclusion. The spray with seawater and brown algae extract is more effective than nasal spray with isotonic solution in the early postoperative period in children after adenotomy.
Academician G.N. Speransky (1873–1969) and Moscow School of Pediatricians. In mark of 50th anniversary of the scientist death day
Authors: Morgoshiya T. Sh. , Markhuliya Kh. M. , Syroezhin N. A. , Balashova Е. D. , Belyaeva D. O. , Inkin A. V.
Published: March 2020

The article presents the main milestones of the life and work of the academician G.N. Speransky, the scientific priorities of the scientist, and the scientific activities of some of his outstanding students. Since 1931, G.N. Speransky, the head of the Department of Pediatrics of the Central Institute for Advanced Medical Studies, is the author of more than 200 scientific papers on the development of the problems of physiology and pathology of early childhood, including the neonatal period. He scientifically substantiated methods of feeding, caring and raising children. G.N. Speransky, together with co-authors, was awarded the Lenin Prize for a series of works on the physiology and pathology of young children. A significant number of his works are devoted to neonatal sepsis, respiratory diseases, and acute gastrointestinal diseases. In 1922, G.N. Speransky organized journal “Pediatrics”, he was the editor for 47 years. G.N. Speransky was also the editor of the Pediatrics section of the 1st and 2nd editions of the Big Medical Encyclopedia, chairman of the All-Union Society of Pediatricians.
Psychosomatic comorbid conditions in children with enuresis
Authors: Letifov G. M. , Boiko N. V. , Letifova N. G.
Published: March 2020

Enuresis is a considerable medical and socio-psychological problem. The pathophysiology of enuresis remains unknown; none of the existing theories can explain its nature in full. The article reviews the studies devoted to the role of obstructive sleep disturbances in the occurrence of enuresis. The mentioned sleep disturbances in children are associated with other related disorders: pulmonary hypertension, developmental delay, sleepwalking, attention deficit and hyperactivity disorder, obstructive sleep apnea syndrome and enuresis. Numerous studies confirm the correlation of the mentioned syndromes. The obstruction of the upper respiratory tract during sleep is accompanied by an increase in the efforts of the respiratory muscles and negative intrathoracic pressure, which is associated with high atrial natriuretic peptide and low antidiuretic hormone levels. In most cases the surgical removal of respiratory tract obstruction (adenotonsillectomy) leads to significant improvement or complete resolution of enuresis. This category of patients requires a comprehensive interdisciplinary approach to the examination and treatment by the pediatricians, psycho-neurologists and ENT specialists.
Assessment and mitigation of credit risks in project financing
Authors: Naumenkova Svitlana , Tishchenko Ievgen , Mishchenko Svitlana , Mishchenko Volodymyr , Ivanov Viktor
Published: March 2020

Lending to long-term investment projects in fragile countries requires additional financial instruments to control the sustainability of project cash flows and to increase the borrower’s financial discipline in debt servicing. This paper analyzes the special aspects of using financial covenants as credit risk mitigation instruments in project financing in Ukraine. It also argues that regulatory requirements to maintain financial strength indicators at the appropriate level have an indirect impact on the change in project finance loan rates. The study primarily aims at developing approaches to defining a credit rate corridor for an investment project, depending on changes in the values of financial sustainability indicators. The implementation of the proposed approach allows increasing the validity of credit risk components for investors and optimizing capital value for borrowers.As required by international practice, violation of covenant terms is the trigger for satisfying the creditors’ claims. According to the authors’ conclusions, the use of financial covenants as a tool for protecting the creditors’ interests should not be an instrument of unreasonable financial pressure on borrowers. The study reveals benefits and drawbacks of using financial covenants to mitigate credit risk and reduce the probability of a borrower default in the field of project financing in Ukraine.
Optimization of boron removal from water by electrodialysis using response surface methodology
Authors: Guesmi Fatma , Louati Islem , Hannachi Chiraz , Hamrouni Béchir
Published: March 2020

Boron removal from water containing 5 mg L−1 of boron using electrodialysis (ED) was studied as a function of several parameters such as flow rates, initial pH, coexisting anions and ED time. An ED cell, equipped with three cation exchange membranes (fumasep FKB) and two anion exchange membranes (fumasep FAB), was applied. The central composite design, which is the standard design of response surface methodology, was used to evaluate the effects and interactions of studied factors on boron removal efficiency. The effectiveness of the considered design parameters was well examined to find the optimum condition. The experimental data obtained were analyzed by analysis of variance for the polynomial model with 95% confidence level. Boron removal by ED showed to be independent of the electrodialysis time, whereas flow rate as well as the pH of the feed solution and also the coexisting anions on the feed solution play a significant role on the deboronation efficiency. According to the desirability function, the maximum response of 43.5% was predicted for boron removal at a pH equal to 10, a flow rate of 10 L h−1, a ratio between sulfates and that of boron equal to 2 and a reaction time of 25 minutes.
Discovery of Anticancer Agents from 2-Pyrazoline-Based Compounds
Authors: Li Qing-Shan , Shen Bang-Nian , Zhang Zhen , Luo Shuying , Ruan Ban-Feng
Published: March 2020

As nitrogen-containing five-membered heterocyclic structural units, the substituted pyrazole
derivatives have a broad spectrum of pharmacological activities, especially 4,5-dihydro-1H-pyrazoles
that also commonly known as 2-pyrazolines. Since 2010, considerable studies have been found that the
2-pyrazoline derivatives possess potent anticancer activities. In the present review, it covers the pyrazoline
derivatives reported by literature from 2010 till date (2010-2019). This review aims to establish
the relationship between the anticancer activities variation and different substituents introduced into a
2-pyrazoline core, which could provide important pharmacophore clues for the discovery of new anticancer
agents containing 2-pyrazoline scaffold.
MiR-509-3-5p-NONHSAT112228.2 Axis Regulates p21 and Suppresses Proliferation and Migration of Lung Cancer Cells
Authors: Liang Jing-Jing , Wang Jun-Yi , Zhang Tong-Jia , An Guo-Shun , Ni Ju-Hua , Li Shu-Yan , Jia Hong-Ti
Published: March 2020

Background:

Although the involvement of individual microRNA and lncRNA in the regulation
of p21 expression has largely been evidenced, less is known about the roles of functional interactions
between miRNAs and lncRNAs in p21 expression. Our previous work demonstrated that miR-509-
3-5p could block cancer cell growth.

Methods:

To gain an insight into the role of miR-509-3-5p in the regulation of p21 expression, we performed
in silico prediction and showed that miR-509-3-5p might target the NONHSAT112228.2, a
sense-overlapping lncRNA transcribed by a non-code gene overlapping with p21 gene. Mutation and
luciferase report analysis suggested that miR-509-3-5p could target NONHSAT112228.2, thereby blocking
its expression. Consistently, NONHSAT112228.2 expression was inversely correlated with both
miR-509-3-5p and p21 expression in cancer cells. Ectopic expression of miR-509-3-5p and knockdown
of NONHSAT112228.2 both promoted proliferation and migration of cancer cells.

Results:

Interestingly, high-expression of NONHSAT112228.2 accompanied by low-expression of p21
was observed in lung cancer tissues and associated with lower overall survival.

Conclusion:

Taken together, our study found a new regulatory pathway of p21, in which MiR-509-3-5p
functionally interacts with NONHSAT112228.2 to release p21 expression. MiR-509-3-5p—
NONHSAT112228.2 regulatory axis can inhibit the proliferation and migration of lung cancer cells.