bluuebunny/crossref_metadata_2025 huggingface dataset:
COMPARISION OF ONSET OF ACTION, DURATION AND INTUBATING CONDITIONS OF ROCURONIUM BROMIDE AND SUCCINYLCHOLINE IN ADULT PATIENTS.
Authors: Kumar Prashant , Srivastava Sharad , Bhardwaj Manu
Published: June 2023

Background: The major uses of muscle relaxation for surgery are: to facilitate endotracheal intubation and to provide surgical relaxation. Succinylcholine, with its rapid onset time, excellent intubating conditions, and short duration of action is a favourite of many anaesthesiologists for rapid endotracheal intubation. However, it falls short of the status of the ideal muscle relaxant - due to its life-threatening side effects such as hyperkalaemia, cardiac arrest and malignant hyperthermia. Rocuronium may serve as a useful alternative for many clinicians to facilitate endotracheal intubation, not only in elective cases under adequate anaesthesia, but also in emergency situations requiring rapid sequence intubation. The side effect prole of Rocuronium is way more limited, and way more acceptable to that of succinylcholine. While there have been many studies on the dosage of Rocuronium greater than /equal to 1mg/kg, which have demonstrated comparable onset and intubating conditions to succinylcholine, this study involves a lower dose(0.9mg/kg) elective surgery cases, where a minor difference in the time of onset is of no signicant concern. Objective: To compare onset of action, duration and intubating conditions of Rocuronium Bromide (0.9mg/kg) and Succinylcholine (1.5mg/kg) in adult ASA I and II patients posted for elective surgery. Method: this was a randomized, double-blind, prospective, clinical study conducted on 100 ASAI and II patients posted for elective surgery. Patients were divided into two groups using 'slips in the box technique': Group A– received Rocuronium bromide 0.9 mg/kg Group B – received Succinylcholine 1.5mg/kg Results: Ÿ The intubating conditions using Goldberg's score were acceptable in both groups= excellent or good conditions. Ÿ But the Succinylcholine group had more instances of excellent intubating conditions, and this difference was statistically signicant. p<0.05 Ÿ The Mean arterial pressure increased after laryngoscopy in both groups, but its difference between the two groups was not statistically signicant at any time interval. p >0.05 Ÿ In the Rocuronium group, 6 patients had signicant tachycardia. HR>120, and 5 patients had hypotension (MAP<60mm Hg) Ÿ In the Succinylcholine group, 7 patients had signicant tachycardia. HR>120, and 6 patients had hypotension (MAP<60mm Hg). Conclusion: this study reveals that Rocuronium, at a dose of 0.9mg/kg, is an effective substitute for Succinylcholine as the choice of muscle relaxant, and offers similar intubating conditions, at 1 minute. Considering the lower side effect prole, Rocuronium at the dose of 0.9 mg/kg can be the ideal choice for muscle relaxant during elective surgery
COVID 19 VACCINATION COVERAGE AND ITS ADVERSE EVENTS AMONG GENERAL POPULATION OF CENTRAL INDIA- A CROSS SECTIONAL STUDY
Authors: Kumare Sachin , Bagdey Prashant , Jadhao Ashok , Agrawal Sanjay
Published: June 2023

Background: The ongoing pandemic of Corona virus disease 2019(covid-19) is caused by Severe acute respiratory syndrome Corona virus 2(SARCOV-2). The World Health Organization declared it as public health emergency of international concern on January 2020, and later declared as pandemic on 11 March 2020. Indian population are less aware of the pandemic and have less access to health care facilities. Vaccinating these populations can decrease disease burden and control the on-going pandemic. Aim and Objectives: To study AEFI pattern following COVID- 19 vaccination in populations of central India. To estimate the COVID 19 vaccination coverage in general populations of central India. To assess the factorsresponsible for COVID 19 vaccination coverage. Material and Methods: Acommunity based crosssectionalstudy will be conducted among 350 participantsresiding in the eld practice area of Urban and Rural Health care Training Centre of tertiary medical college of Nagpur from January 2022 to February 2022. Data is collected using structured interview questionnaire after obtaining informed consent. Data is entered in Excelsheet and SPSS 20 for analysis. Analysis will be done using Chi square test and a p Value of <0.05 will be taken as signicant. Results: In the present study, 84.31% (301 out of 357) of the study participants had taken COVID Vaccine, of which 217 (60.78%) were partially vaccinated and remaining 80 (23.52%)were fullyVaccinated.Most ofthe vaccinated study participants had takenCovishield vaccine 237 (78.73%)followed byCovaxin vaccine 62 (20.59%). And 16.52% were aware about AE reporting however those who aware of them 20% report Adverse events. The percentage of The AEFI st nd experienced after 1 dose was 112 (51.61%) and 2 dose was 30 (35.71%). Fever and general fatigue were the most common AEFI experienced. Conclusion: The COVID vaccine coverage was good in general population.Although adverse events due to vaccines were reported during the survey none of the eventsreported were severe orserious, which reiteratesthat the vaccines used in India are safe and the events will last without any kind of sequelae.Studies ofthis nature reinforce theneedfor vigilant monitoring and reporting of AEFIs
ASSOCIATION OF HELICOBACTER PYLORI WITH PEPTIC PERFORATION
Authors: Sekhar Kar Himadri , Kuila Satyaprakash , Pachal Sumitava , Saha Gaurav
Published: June 2023

Background: Helicobacter pylori infections have been proved to be associated with peptic ulcer disease, gastritis, gastric adenocarcinoma, gastric lymphoma. The role of Helicobacter pylori is not well established in cases of peptic perforation. The objective of this study is to observe the presence or absence of Helicobacter pylori in cases of perforated peptic ulcer. Methods: We have done a cross sectional observational study with data from patients presenting to the emergency of a tertiary care hospital with perforated peptic ulcer and undergoing emergency exploratory laparotomy followed by omental patch repair. We collected mucosal biopsy samples from gastric/duodenal mucosa along margin of perforation site of these patients and performed rapid urease test using Rapid Urease Test kit. Of the 50 participants in our study, 48 (96%) were males Results: and 2 (4%) were females. 37 (74%) cases had perforation at pre pyloric region, and in 13 (26%) cases perforation was present at rst part of duodenum. Rapid urease test by Rapid Urease Test kit was found to be positive in 6 (12%) cases and negative among 44 (88%) cases. Conclusion: In our study, frequency of Helicobacter pylori in perforated peptic ulcer cases was found to be only 12% which proves that there may be other contributing factors in perforated peptic ulcer cases, which need further evaluation. Objective: To assess the presence of Helicobacter pylori in mucosal surface of stomach and duodenum in patients undergoing emergency exploratory laparotomy followed by omental patch repair in patients of peptic perforation.
COMPARISON OF 3D T2-WEIGHTED SEQUENCE WITH CONVENTIONAL 2D MRI SEQUENCES IN THE ASSESSMENT OF SHOULDER JOINT PATHOLOGIES
Authors: Reddy Mallapu Ritesh , Karumathil Pullara Sreekumar
Published: June 2023

Background: Conventional 2D MR protocol routinely used in the institutions for assessment of shoulder joint pathologies have good tissue contrast and in-plane spatial resolution, but they must be repeated in several planes which takes more examination time, and the thicker slices can miss some pathologies due to partial volume averaging. Instead, procuring thin slices is possible with 3D acquisition and can be post-processed into other planes using multiplanar reformation techniques, thereby reducing overall examination time and provides good patient compliance, fewer motion artefacts. This study's goal is to determine the agreement between conventional 2D sequences and 3D T2 weighted sequence in the assessment of rotator cuff and other shoulder joint pathologies. 50 patients with suspected shoulde Methods: r joint pathologies were examined with 2D and 3D protocol in the same session. In the assessment of shoulder joint pathologies, agreement between T2-weighted 3D sequence and conventional 2D sequences is evaluated with kappa statistics. Diagnostic accuracy of T2-weighted 3D sequence with conventional 2D sequences as standard of reference is evaluated using McNemar and Chi square test. Perfe Results: ct agreement (k=1.00) between 2D and 3D sequences seen in the assessment of full thickness tears of supraspinatus and infraspinatus, partial thickness tears of subscapularis, tendinitis of rotator cuff muscles, biceps tendon, AC joint, bursitis and joint effusion. Strong agreement is seen with assessment of partial thickness tears of supraspinatus (k=0.811), moderate agreement with articular cartilage lesions (k=0.79) and bone marrow edema (k=0.779). Perfect agreement is Conclusion: seen between 2D and 3D sequences in the assessment of most of the rotator cuff and other shoulder pathologies in our series. With 3D sequence being capable of reducing overall examination time, it provides more patient compliance and reduced motion artefacts. We recommend further studies with arthroscopy as gold standard before relying purely on 3D sequence for shoulder evaluation.
CORONARY ARTERY BYPASS SURGERY IN YOUNG ADULT A INSTITUTIONAL RETROSPECTIVE STUDY
Authors: Senthil V. , Sanjeev Pandian R.
Published: June 2023

Objective: To study the overall causes, perioperative mortality, post operative complications, prognosis, outcome and follow up in a young adult present with coronary artery disease under going coronary artery bypass in our institute. Methods: Asum of 56 patient who are 40 years and less then 40 years who underwent coronary artery bypass surgery between January 2017 to December 2022 who's clinical case history, coronary angiography, pre operative and post operative echo cardiography, operative notes, post operative notes, outpatient follow up are collected from our computer stored data and from medical record department in our college and from Tamilnadu chief minister comprehensive health insurance scheme institutional Web site data base Results: Out of 56 patient,8 Female(14.3%) and 48 Male(85.7%),mean age 37.1 years (range 32 – 40 years),Diabetic 39 Patient (62.5%),Hypertensive 21 patient (37.5%) 7 / 8 women(87.5%) diabetic ,3/8 women both diabetic and hypertensive. Out of 48 male 47(97.9%) chronic smoker, 45 (93.8%) chronic alcoholic,44 (91.6%) both alcoholic and smoke , no women in this study neither alcoholic or smoker, 3patient (5.35%) hyperlipidaemia, 2 patient (3.57%) hypothyroidism all 2/8 (25%) are female,2 patient on haemodialysis for kidney disease, 1patient with bilateral renal artery stenosis, 1 patient with right innominate, right subclavian, bilateral carotid stenosis. Left ventricular function was impaired with ejection fraction average 46% (range 30% - 55%). 1 patient with ventricular septal rupture.2 patient with post coronary stent, The indication for surgery was triple vessel disease in 30 patient(53.57%) ,double vessel disease in 20 patient(35.7%),single vessel disease in 1 patient, single vessel disease with ventricular septal rupture in 1 patient, left main coronary artery stenosis in 4 patient(7%). Surgical procedure Off pump coronary artery bypass surgery in 51 patient(91%), On pump beating heart coronary artery bypass surgery in 2 patient (3.57%),On pump arrested heart coronary artery bypass surgery in 3 patient(5.35%). A total of 132 grafts were constructed(mean 2.4 grafts per patient),35 (27%) of them being arterial only left internal mammary artery harvested and other grafts were great saphenous vein. Post operative average ventilation time18hrs (range 18hrs to 24hrs), There were 5(8.9%)hospital death and 5(8.9%) late death in follow up, total 10 (17.8%) death till now. Conclusion: Most common cause for young coronary artery disease from our clinical history is found to be early onset diabetic mellitus and from our personal history chronic smoking and chronic alcoholism, intra operative mortality and morbidity is high in patient present with severe left ventricular dysfunction, coronary artery diseases induced complication and additional comorbidity, however most of patient recovered from post operative cardiovascular lethal or morbid event and on regular clinical follow up
CLINICO-ETIOLOGICAL PROFILE OF FIRST EPISODE OF SEIZURE AND ITS CORRELATION WITH ELECTROENCEPHALOGRAM AND IMAGING SPECTRUM IN CHILDREN AGED ABOVE 5 YEARS OF AGE IN A TERTIARY CARE HOSPITAL: A PROSPECTIVE OBSERVATIONAL STUDY
Authors: M Kavya , Patil Jayaraj
Published: June 2023

Seizures, a transient occurrence of signs and/or symptoms resulting from abnormal excessive or synchronous neuronal activity in the brain [1, 2].Seizure is one of the commonest neurological illnesses. About 4-10% of children experience at least one episode in the rst 16 years of life. Where 1/5th of total children with unprovoked seizures may develop epilepsy. Risk is approximately 20% if neurological examination, electroencephalogram (EEG) and neuroimaging is normal[1]. EEG abnormalities can be detected in up to 59% of children with rst afebrile seizure and can identify subtle focality in presence of normal magnetic resonance imaging of brain[1]. Neuroimaging has an important role in children with focal seizure, persistent seizure activity, focal neurologic decit, neurocutaneous disorder etc.Right assessment and scrutiny of rst seizure is crucial, not only for abortion of acute attack but also for long term control of epilepsy. Aim and methods- The objective of the study is to determine the age of onset, etiology of rst episode of seizure in children between the age group of above 5 yearsto15 years and the pattern of EEG changes and MRI ndings in the above group of children. In a prospective single centre observational study at GIMS GADAG, around 60 children who were admitted with rst episode of seizure at age group of above 5 years to 15 years to our emergency department between October 2021 to July-2022 (10 months) were studied. Seizures dened using international league against epilepsy (ILAE). EEG and MRI were done in all 60 children and their records were analysed. Results- A total of 60 children presenting with rst episode of seizures were included in the study. 9-12 year age group were major portion of our study with male gender predominance. Generalized seizures were more common accounting for 78%. Idiopathic seizure was the most common etiology identied (40%), followed by meningitis (27%) and other causes. EEG abnormality was seen in 50% of the children.
Исследования хлебопекарных свойств муки ржаной хлебопекарной обдирной, поставляемой на хлебопекарные предприятия РФ
Authors: Носова Марина Владимировна , Дремучева Галина Федоровна
Published: June 2023

Введение. В РФ хлеб из ржаной муки - традиционный продукт питания, который является источником многих ценных для человека пищевых веществ: витаминов В1, В2, В9, РР, минеральных веществ – фосфора, железа, марганца, меди, селена и др. По внешнему виду, характеристикам мякиша,  вкусу и запаху хлеб должен быть аппетитным и соответствовать требованиям ГОСТ или ТУ на конкретное изделие. В настоящее время, по данным ФГАНУ НИИХП, Роскачества РФ и средств массовой информации,  в торговые предприятия для реализации населению  поступает определенная  доля  хлебобулочных изделий  из ржаной муки и смеси ее с пшеничной с дефектами (малым объемом,  не эластичным, крошащимся или комкующимся при разжевывании  мякишем,  не выраженным запахом и др.). Очевидно, что для оценки хлебопекарных свойств муки необходимы методы, позволяющие получить критерии, которые с высокой степенью достоверности обеспечивают объективную характеристику того или иного свойства муки. Однако по мнению ученых ФГАНУ НИИХП и технологов хлебопекарных предприятий некоторые методы определения хлебопекарных свойств ржаной муки, установленных стандартом качества, недостаточно информативны. Целесообразна верификация показателей хлебопекарных свойств ржаной муки, а также включение дополнительных показателей и методов для более полной оценки хлебопекарных свойств ржаной муки.Цель. Исследование хлебопекарных свойств 41-ой пробы муки ржаной хлебопекарной обдирной, поставленной на ряд хлебопекарных предприятий РФ и обоснование необходимости совершенствования методологической базы и технологических решений повышения качества и безопасности хлебобулочных изделий, экологичности и конкурентоспособности производства. На основе полученных результатов выдать рекомендации по уточнению норм некоторых показателей качества, предусмотренных ГОСТ 7045, а также с учетом данных научно-технической литературы рекомендовать дополнительные показатели качества ржаной муки. Материалы и методы. В работе использовали 41 пробу ржаной хлебопекарной обдирной муки, предоставленных в ФГАНУ НИИХП хлебопекарными предприятиями РФ. Качество муки определяли по методам, предусмотренным стандартами ГОСТ (массовую долю влаги, белизну, число падения, зольность, крупность помола, цвет, запах, вкус и наличие минеральной примеси.   Дополнительно определяли амилолитическую активность муки на приборе Амилограф и количество белка.Результаты. Исследуемые пробы муки по влажности и органолептическим показателям отвечают требуемым показателям качества, однако по физико-химическим показателям, а также по количеству белка, соответствуют требованиям только четыре пробы муки, остальные пробы не соответствуют стандарту от одного до четырех показателей. Выводы. Проведенные исследования свидетельствуют также о том, что методы определения крупности и автолитической активности муки не обеспечивают должную информативность характеристик указанных показателей, что вызывает необходимость корректировки их или разработки новых более репрезентативных методик.
Влияние продуктов переработки конопли и природы белка в стеновом материале эмульсионного геля на качество и структуру заварного полуфабриката для эклера
Authors: Васькина Валентина Андреевна , Шаршунов Вячеслав Алесеевич , Машкова Ирина Анатольевна , Быков Александр Андреевич , Щеголева Ирина Дмитриевна
Published: June 2023

Введение. Основными недостатками технологии заварного полуфабриката для эклеров и профитролей является использование твердых животных жиров и высокие требования к пшеничной муке по количеству и качеству клейковины. Замена твердого жира на конопляное масло и пшеничной муки на безглютеновую смесь из конопляной и рисовой муки позволит получить продукт, обогащенный уникальным комплексом питательных веществ, и снизить риски ряда заболеваний. Однако, указанные замены рецептурных компонентов приведут к принципиальному изменению структурной основы теста и применению новых технологических решений.

Цель работы. Использование в технологии заварного полуфабриката белково-полисахаридных смесей и продуктов переработки семян конопли – масла и муки, проведение оценки их влияния на качество и структуру заварного полуфабриката.

Материалы и методы. Опытные образцы заварного полуфабриката готовили с заменой пшеничной муки на безглютеновую смесь из конопляной и рисовой муки и твердого животного жира – на конопляное масло. Необходимое структурообразование в тесте достигалось за счет введения белково-полисахаридных смесей, в которых использовали сухую молочную сыворотку или изолят белка сои и тройную смесь полисахаридов – альгинат натрия, пектин, натрий карбоксиметилцеллюлозу. Проведены исследования физико-химических, органолептических и рентгеноструктурных характеристик заварного полуфабриката в зависимости от технологии и рецептуры приготовления.

Результаты. Экспериментально доказана возможность получения заварного полуфабриката для эклеров и профитролей с высокими питательными свойствами по новой технологии, согласно которой пшеничную муку полностью заменяют безглютеновой смесью, состоящей из конопляной и рисовой муки в соотношении 50:50, а вместо твердого животного жира вносят конопляное масло, капсулированное в оболочки из белково-полисахаридных смесей. Готовые изделия имели хорошие физико-химические и органолептические характеристики. Отмечено, что изделия обладали немного более темным цветом поверхности, приятным вкусом и ароматом, а также более однородной структурой стенки, окружающей внутреннюю полость.

Выводы. Полученные результаты могут быть использованы для совершенствования технологий мучных кондитерских изделий с привлечением новых источников ценного растительного сырья.
A Laplace Domain Model Implementation in System Verilog for Top Level Functional Verification
Authors: McMitchell Daniel
Published: June 2023

In top level functional verification of mixed-signal VLSI systems, special efforts are required to adequately model the design’s analogue portions to maximise verification coverage in a reasonable regression runtime. Although generally one will want to avoid modelling analogue frequency domain behaviour where possible, in some contexts – including, for stability reasons, closed-loop mixed-signal systems – it may be necessary. This paper presents a System Verilog implementation of a system described by arbitrary Laplace coefficient parameters; appropriate for modelling a frequency-dependent analogue path.
A Proposed Quantum Framework for Low-Complexity Quantum Simulation and Spectrum Estimation of Hankel-Patterned Systems
Authors: Laskar Mostafizur Rahaman , Dutta Amit Kumar
Published: June 2023

This work has been submitted for possible publication. Copyright may be transferred without notice, after which this version may no longer be accessible.
Challenges In Data Communication and Networking
Authors: JUMAIRI MUHAMMAD DANIEL ALIF
Published: June 2023

This paper discussing about challenges in data communication and networking. This paper also gives solution about how to tackle this challenges. 
Cyberbiosecurity in High-Containment Laboratories
Authors: Crawford Elizabeth , Bobrow Adam , Sun Landy , Joshi Sridevi , Vijayan Viji , D. Blacksell Stuart , Tensmeyer Nicole
Published: June 2023

High-containment laboratories (HCLs) conduct critical research on infectious diseases, provide diagnostic services, and produce vaccines for the world’s most dangerous pathogens, often called high-consequence pathogens (HCPs). The modernization of HCLs has led to an increasingly cyber-connected laboratory infrastructure. The unique cyberphysical elements of these laboratories and the critical data they generate pose cybersecurity concerns specific to these laboratories. Cyberbiosecurity, the discipline devoted to the study of cybersecurity risks in conjunction with biological risks, is a relatively new field for which few approaches have been developed to identify, assess, and mitigate cyber risks in biological research and diagnostic environments. This study provides a novel approach for cybersecurity risk assessment and identification of risk mitigation measures by applying an asset-impact analysis to the unique environment of HCLs. First, we identified the common cyber and cyberphysical systems in HCLs, summarizing the typical cyber-workflow. We then analyzed the potential adverse outcomes arising from a compromise of these cyber and cyberphysical systems, broadly categorizing potential consequences as relevant to scientific advancement, public health, worker safety, security, and the financial well-being of these laboratories. Finally, we discussed potential risk mitigation strategies, leaning heavily on the cybersecurity materials produced by the Center for Internet Security (CIS), including the CIS Controls®, that can serve as a guide for HCL operators to begin the process of implementing risk mitigation measures to reduce their cyberbiorisk and considering the integration of cyber risk management into existing biorisk management practices. This paper provides a discussion to raise awareness among laboratory decision-makers of these critical risks to safety and security within HCLs. Furthermore, this paper can serve as a guide for evaluating cyberbiorisks specific to a laboratory by identifying cyber-connected assets and the impacts associated with a compromise of those assets. 
Generalised Modelling of Overactuated Aerial Manipulators: Theory and Application
Authors: Markovic Lovro , Car Marko , Orsag Matko , Bogdan Stjepan
Published: June 2023

This paper proposes a unified dynamic model for aerial robots which encompasses all known actuation principles including tilting propellers and centroid variation methods such as moving masses or robotic manipulators. Of course, one can envision a wide variety of vehicles,  all with different combinations of actuation principles. Therefore, a generalised modelling methodology for such vehicles is developed and presented in this paper. The modelling approach is verified through a comparative analysis of MATLAB simulations and laboratory experiments with a tilting propeller aerial manipulator vehicle, named Toucan. Finally, in order to fully explore and exploit the capabilities of the designed aerial manipulator, contact-based experiments with force tracking are performed using the proposed adaptive impedance controller. To demonstrate the advantages of such a vehicle, the adaptive impedance control method is used to generate position and orientation commands and achieve end-effector force tracking on a flat surface while the aerial manipulator maintains neutral attitude. This greatly increases the stability and safety of contact-based operations, as the vehicle does not require changes in attitude to meet the force requirements.
Improving Reliability of Magnetic Localization Using Input Space Transformation
Authors: Yaldiz Cem , Sebkhi Nordine , Bhavsar Arpan , Wang Jun , Inan Omer
Published: June 2023

The distribution shift due to magnetization differences in magnetometers causes machine learning-based magnetic localization models to be ineffective for the end user. We present a novel post-deployment calibration mechanism to mitigate this issue. 
Co-existence of interfacial and filamentary resistance switching in Ti/SiOx/Au resistive memory devices
Authors: Roy Sourodeep , Chakrabarti Bhaswar , Bhattacharya Enakshi
Published: June 2023

This work reports the development of a resistive random-access memory (RRAM) device with Silicon-oxide (SiOx) active switching material.  Metal-oxide based RRAM synaptic devices typically suffer from high variability and strongly non-linear conductance change. In this work, we demonstrate a SiOx-based synapse with low operating voltages, excellent uniformity in the switching operation, and analog tunability of conductance. The devices also exhibit linear and symmetric conductance update.  

Our investigations reveal that the enhanced uniformity and analog tunability can be attributed to an interfacial switching mechanism which can be controlled through careful optimization of the device operating conditions.
Singularity-Free Lagrange-Poincar ́e Equations on Lie Groups for Vehicle-Manipulator Systems
Authors: Monazzah Moghaddam Borna , Chhabra Robin
Published: June 2023

It has been long known that the Euler-Lagrange dynamical equations of fixed-base manipulators with single-degree-of-freedom joints can be formulated on Lie groups following exponential joint parameterizations. Whereas, dynamics of vehicles can be captured using the Euler-Poincar ́e equations on Lie groups, with no need to choose any local parameterization. We utilize a combined form of these two geometric approaches called the Lagrange-Poincare Equations to develop a singularity-free Lagrangian formalism for the dynamics of vehicle-manipulator systems. We consider vehicles whose configuration manifolds are Lie sub-groups of the Special Euclidean group, encompassing arbitrary base vehicle motions corresponding to, e.g., ball, planar, or free joints. We revisit the Lagrange-d’Alembert principle for systems on principal bundles to derive the Lagrange-Poincare equations for vehicle-manipulators with possibly symmetry-breaking external applied wrenches. These equations effectively separate the external (locked-arm system) and internal dynamics (arm’s motion) by introducing a block-diagonalized inertia matrix. We then incorporate the exponential parameterization of manipulators to explicitly formulate the reduced dynamics on Lie groups. The resulting equations are in matrix form and can be immediately implemented in simulations and model-based control strategies. The geometrical significance of the proposed formalism is further demonstrated via the step-by-step presentation of a case study.
Topic Modeling: Exploring the Processes, Tools, Challenges and Applications
Authors: Taghandiki Kazem , Mohammadi Mohammad
Published: June 2023

Topic modeling is a data analysis technique that has become increasingly popular in recent years due to the growing availability of large datasets. It enables researchers to uncover underlying themes and topics within large and complex datasets by identifying patterns and relationships among data points. This article overviews the topic modeling process, including the algorithms used, tools, evaluation metrics, and applications across various fields. It also discusses potential areas for future research, such as integrating other machine learning techniques and incorporating temporal and contextual information. Overall, topic modeling represents a powerful tool for data analysis that has the potential to unlock new insights and understanding in a variety of domains
PENGARUH MEDIA PEMBELAJARAN PRESENTASI BERBASIS ARTICULATE STORYLINE TERHADAP HASIL BELAJAR PESERTA DIDIK MATERI SPLDV KELAS VIII SMP MUHAMMADIYAH AIMAS
Authors: Pratiwi Iin , Pamungkas Dwi
Published: June 2023

Rendahnya hasil belajar peserta didik pada pembelajaran matematika disebabkan oleh berbagai faktor, salah satunya kurangnya penggunaan media pembelajaran yang mengakibatkan peserta didik lebih cenderung pasif. Penelitian ini bertujuan untuk mengetahui pengaruh media pembelajaran presentasi berbasis Articulate Storyline terhadap hasil belajar matematika peserta didik kelas VIII SMP Muhammadiyah Aimas pada materi SPLDV. Penelitian ini menggunakan metode Eksperiment dengan desain Pretest- Posttest Control group Designi. Populasi dalam penelitian ini adalah seluruh peserta didik kelas VIII SMP Muhamammdiyah Aimas yang terdiri dari 20 peserta didik. Pengumpulan data hasil belajar matematika peserta didik menggunakan instrumen berupa tes. Sedangkan pengolahan data menggunakan uji Paired Sample t test. Berdasarkan uji t dengan taraf signifikan
PENGEMBANGAN INSTRUMEN HIGHER ORDER THINKING SKILL (HOTS) DALAM PEMBELAJARAN MATEMATIKA DI SMP
Authors: Wahyuningsih Ridya Tri , Astutik Heny Sri , Triono Mukhlas
Published: June 2023

Penelitian ini merupakan penelitian pengembangan instrumen HOTS dalampembelajaran matematika untuk peserta didik kelas VIII di SMP. Tujuan penelitian iniadalah (1) mengembangkan instrumen HOTS di SMP.; (2) memvalidasi instrumenHOTS melalui validasi ahli dan guru. Validasi ahli dilakukan denganmengkonsultasikan rancangan produk pengembangan kepada dosen ahli. Validasi gurudilakukan berdasarkan revisi. Penelitian ini menggunakan model Design BasedResearch. Pengembangan model ini terdiri dari 4 tahap yaitu 1) identifikasi dan analisismasalah oleh peneliti peneliti dan praktisi secara kolaboratif 2) mengembangkan solusiyang didasarkan pada teori, design principle yang ada dan inovasi teknologi 3)melakukan proses berulang untuk menguji dan memperbaiki solusi secara praktis 4)melakukan refleksi untuk menghasilkan design principle serta meningkatkanimplementasi dari solusi. Hasil penelitian berupa 1) 15 butir soal HOTS; 2) validasioleh para ahli menyatakan sangat valid dengan perolehan skor penilaian oleh ahlimateri sebesar 4,4 dengan kategori sangat baik dan ahli bahasa sebesar 5 dengankategori sangat baik, sedangkan dalam validasi guru rata-rata perolehan skor penilaiansebesar 4,3 dengan kategori sangat baik.
Regulatory Status of Microbes as Antibiotics: An Overview
Authors: Soni Yogesh , Preeti Sangwan Preeti Sangwan , Sharma Neha , Ahirwar Priyanka , Kamboj Sahdev
Published: June 2023

Regulatory affairs (RA) play crucial roles in the pharmaceutical industry because they are concerned with the lifecycle of healthcare products, they offer strategic, tactical, and operational direction, and they support working within the law to hasten the development and delivery of safe and effective healthcare products to people all over the world. The purpose of regulatory affairs is to create and implement a regulatory strategy to guarantee that the combined efforts of the drug development team result in a product that is acceptable to international regulators while also standing out from the competition. Microorganisms play a vital role in every field of drug such as production of antibiotics, antifungal, anticancer, vitamins, vaccines and enzymes etc. These are some examples where microbial products are widely used. In the present work we will discuss various aspects where microorganisms widely used in production of drug and their regulations in US and India.
Hemichorea-Hemiballismus Revealing Diabetes Mellitus
Authors: Faiza Aziouaz , Mebrouk Y. , Aziouaz F.
Published: June 2023

Nonketotic hyperglycemia is a rare cause of hemichorea-hemiballismus. We report a case hemichorea-hemiballismus secondary to nonketotic hyperglycemia revealing an inaugural diabetes mellitus. A 55 year-old woman, admitted for subacute-onset of continuous involuntary movements in the right upper and lower limb since three days ago. The movements increased with action, decreased with relaxation, and disappeared during sleep. As the condition did not affect her trunk, other limbs, or her face and no other conditions were evident. At admission, the right upper and lower limb was moving involuntarily. The movement was wild, flailing, and repetitive with varied amplitudes and frequencies. No tremor and rigidity were elucidated and cerebellar signs were negative. Laboratory tests revealed diabetes mellitus, with a fasting blood glucose level of 4,60 g/L and a hemoglobin A1C level of 14.0%. The urine examination was negative for ketones. CT of the brain showed left pallidum hyperdensity. The brain MRI revealed hyperintense signal in the left pallidum on T1-weighted images and isointensity on T2-weighted images. Other laboratory results were within the normal range. A diagnosis of hyperglycemia-associated hemichorea-hemiballismus was made. An insulin treatment and oral antidiabetics were instored. She was subsequently discharged after 14 days of hospital stay with improved glycemic control. Three months after, her chorea-ballismus was completely resolved. A control of brain MRI six month after showed marked improvement in the putaminal changes. Vigilance for this cause of hemichorea-hemiballism is important, since the movement disorder may be the presentation of potentially dangerous underlying hyperglycemia.
A Bilateral Quadricipital Tendon Rupture in a Patient with Chronic Renal Failure
Authors: benabbouha Sallahi HichamAbdellatif , Mohamed AKhouayri , Rifki Fayssal , Lahrech Mehdi , Margad Omar
Published: June 2023

Bilateral quadricipital tendon rupture is a rare lesion, especially in patients with different chronic diseases. We report the case of a bilateral rupture of the quadricipital tendon in a young patient followed for chronic renal failure on hemodialysis for 17 years. Surgical repair was successfully performed using bone sutures and reinforcement by metal framing. We present our results with a literature review.
Early Warning System Of Water Quality Changes In Fishponds
Authors: Subandri Muhammad Asep , Danuri Danuri
Published: June 2023

This study aims to develop an early warning system for changes in water quality in fish ponds using the MQTT and Telegram Bot protocols. Poor water quality can cause significant economic losses in fish farming. Therefore, a system is needed that can accurately and quickly detect changes in water quality and provide warnings to fish farmers. The method used in this study involves the installation of sensors that are connected to a microcontroller and a communication system using the MQTT protocol. The sensors used include temperature sensors, pH sensors, turbidity sensors, water level sensors, and salinity sensors. The data obtained from these sensors will be sent via the MQTT protocol to the server connected to Telegram Bot. Telegram Bot is used as an interface for users. This bot will receive data from the server and perform processing to evaluate the water quality in fish ponds. If a significant change in water quality parameters is detected, the bot will send an early warning to fish farmers via Telegram messages. Fish farmers can receive these alerts on their mobile devices, so they can quickly take the necessary action to improve water conditions. The results of this study indicate that the developed early warning system can provide fast and accurate warnings of changes in water quality in fish ponds. With this system, fish farmers can take the necessary actions to prevent losses caused by changes in water quality before more serious damage occurs. In addition, the use of Telegram as a communication platform allows fish farmers to receive alerts on their mobile devices, which increases the responsiveness and convenience of water quality monitoring.
Validation of the Teaching Beliefs Scale of postmodern Physical Education
Authors: Shih Wei-Yuan , Pu Yih-Lih , Ho Tu-Kuang
Published: June 2023

For physical education (PE) teachers, teaching beliefs are vital to improving students’ aptitude, encouraging teachers and students to develop an equal relationship, and identifying and eliminating the differences between students’ perspectives and learning styles through consultation and dialogue to improve and advance teaching. Therefore, developing a PE-related teaching belief scale from a postmodern perspective is essential for PE development. This study adopted stratified random sampling to select 144 PE teachers for the exploratory factor analysis. We distributed a second round of questionnaires to 418 PE teachers from Taipei, who were randomised into two clusters for confirmatory factor analysis in terms of competing models (n=209) and cross-validation (n=209). The Teaching Beliefs Scale of Postmodern Physical Education demonstrated satisfactory reliability and validity. The internal model structure showed factor loadings of .70–.90, composite reliability values of .89–.94, and average variance extracted values of .62–.74. In adherence to the concept of postmodernism, all statistical data met the threshold conditions and hierarchy, and the four constructs (innovation, reflection, pluralism and criticism) were met. In the future, this scale can be applied to evaluate the development of teachers’ beliefs about teaching PE in the postmodern era.
مقومات توطن صناعة طحن الحبوب مطحنة الدورة انموذجاً
Authors: م.د. ستار جبار خليفه
Published: June 2023

تعد صناعة طحن الحبوب من اقدم الصناعات واشهرها فقد عرفها الانسان منذ زمن بعيد، إذ تم استعمال الحجر للطحن ثم استعمل الماء والهواء لإدارة الطواحين إلى أن تم استعمال المكائن والآلات المتمثلة بالسلندرات والسفترات التي تعمل بالطاقة الكهربائية، كما شهدت هذه الصناعة تطوراً كبيراً في العراق على مر العصور التي مرت عليه لاسيما في النصف الثاني من القرن العشرين، نتيجة ازدياد اعداد السكان ولكونها تشكل الغذاء الاساسي للإنسان، إذ تم اقامة عدة مطاحن في بغداد وباقي محافظات أخرى، منها مطحنة الدورة التي تم تأسيسها عام 1979 التابعة للشركة العامة لتصنيع الحبوب، وتمر هذه الصناعة بعدة مراحل ابتداءً من استلام المادة الخام (الحنطة) من السايلوات إلى ان يتم طحنها وتحويلها للطحين ليعبأ وينقل إلى الوكلاء ومن ثم يوزع على المواطنين، ولأهمية هذه الصناعة كان لابد من دراسة مقومتها الجغرافية ومعرفة مدى مساهمة تلك المقومات في توطنها، إذ ان هنالك عدة مقومات تشكل عامل اساسي في مدى نجاحها ومنها عامل المواقع ومدى توفر المياه والطاقة الكهربائية والوقود، وعامل النقل الذي يعد من العوامل المهمة التي تسهم في نجاحها كونها تستعمل مواد اولية كبيرة ورخيصة الثمن، فضلاً عن السياسة الحكومية وتدخلات الدولة المباشرة وغير المباشرة فيها.
البناء الفني والأساليب البلاغية في قصيدة نكبة دمشق أحمد شوقي
Authors: أ.م.د. سلطان سعيد مربع أبو دبيل
Published: June 2023

أحمد شوقي فارس انقادت كلماته وتوالت حروفه انقياد الفرس لفارسها، توّج الكلمة ملكةً، فتوجته أميراً. ذكره ابن رشيق في باب احتماء القبائل بشعرائها بكتابه " العمدة في محاسن الشعر وآدابه"كانت القبيلة من العرب إذا نبغ فيها شاعر أتت القبائل فهنأتها، لأنه حماية لأعراضهم، وتخليد لمآثرهم، وإشادة بذكرهم، وكانوا لا يهنئون إلا بغلام يولد، أو شاعر ينبغ، أو فرس تنتج" عُرف بمواقفه الوطنية التي أثرت الأدب، فكان شعره منارةً ومنبراً. حمل وطنه جرحاً نازفاً وبرى قلمه سيفاً باتراً، أُغرم بدمشق فخطب وها، وكان نعم المؤنس في حزنها ووحدتها ونضالها ضدّ أعدائها الذين دنسوا ترابها وفضّوا بكارتها.  وقف في سور الأزبكية عام 1926م في مناسبة خُصصت لمساعدة أهل سورية بعدما قُصفت أرضهم ودُمرت، فأبدع قصيدته "نكبة دمشق" التي تجلت فيها أحاسيسه صادقة جيّاشة، متراصة المعاني قوية السبك، دون تكلف، حية، جميلة، معبرة، فائضةً بالأساليب الفنية البلاغية، جامعة بين الخبر والإنشاء. خاطب فيها التاريخ والجغرافيا، وتساءل عن وقع النكبة على بردى، فكيف لأم أنجبت الأبطال أن تصبح عقيماً، موصلاً صوته للعالم. وفي النهاية توصل البحث الى النتائج الاتية: قصيدة نكبة دمشق قصيدةً زاخرة بالمعاني الوطنيّة القوميّة، نستشف من خلالها الشخصيّة الحقيقة لأمير الشعراء وهمه القومي والوطني، فوطنه الذي حمله بقلبه جرحاً ودمعه، بكى لبكائه وحزن لمصابه، فاستحق لقب أمير الشعراء لأنه أمير الكلمات وراعي المعاني. وكذلك تعتبر قصيدة نكبة دمشق وثيقة تاريخيّة حقيقيّة تُجسد من خلالها تاريخ سوريا وتنقله نقلاً أميناً، بماضيها المشرف البعيد – والقريب الأليم الذي جّسد النكبة بكل صورها من طمع الغزاة وإسفاف الفرنسيين، كما صور شجاعة أبناءها وقوتهم.
فاعلية القياس التكيفي متعدد المراحل باستخدام طريقة دلتا لتقدير الدرجات
Authors: أ.  رضا أمين غالب مرجان  , أ.د. إسماعيل سلامة البرصان
Published: June 2023

هدفت هذه الدراسة إلى الكشف عن فاعلية القياس التكيفي متعدد المراحل باستخدام طريقة دلتا لتقدير الدرجات. وقد تم استخدام البيانات الناتجة عن تطبيق اختبار أوتيس لينون للقدرة العقلية العامة المستوى المقدم الصورة (J) على طلبة جامعة إب. وبلغ حجم عينة التدريج (1600) طالباً وطالبة، حيث تم تدريج البيانات باستخدام برنامج دلتا. وقد تكونت عينة القياس التكيفي من (130) مفحوصاً، استُخدمت بيانات استجاباتهم في القياس التكيفي الذي تكون من أربع مراحل. تكونت المرحلة الأولى من خمس مفردات، تلاها المراحل الثانية والثالثة والرابعة وتكونت كل منها من خمس مفردات أيضاً. ومن ثم تم حساب الدرجة لكل مفحوص في المراحل الأربع بشكل تراكمي، وتم مقارنتها بدرجة المفحوص المقدرة من الاختبار الخطي بمفرداته الثمانين. وأظهرت النتائج أن معامل الارتباط بين الدرجة المقدرة من الاختبار التكيفي والدرجة المقدرة من الاختبار الخطي بمفرداته الثمانين كان مقداره (0.878)، ومتوسط الفروق في الدرجة المقدرة كان بمقدار (5.728). كذلك بلغ الخطأ المعياري في المتوسط (0.096)، إضافة إلى ان الفرق بين الجذر التربيعي لمتوسط مربعات الخطأ في المتوسط كان (0.053)، الأمر الذي يفيد بفاعلية القياس التكيفي المبنى باستخدام طريقة دلتا.
الكفاح التحصيلي وعلاقته بتحمل المسؤولية الاجتماعية لدى طلبة الجامعة
Authors: م.د. حوراء سلمان جاسم البناء
Published: June 2023

ان طلبة الجامعة يواجهون تغيرات كثيرة، خصوصاً ان مرحلة الجامعة هي مرحلة تقرير مصير بالنسبة لهم، من حيث التصميم على مواصلتهم للدراسة، واختيارها للتخصص الذي يتناسب قدراتهم وميولهم، وبنفس الوقت فهم يتحدون الظروف الصحية الراهنة من أزمة كورونا، ويُعدُّ الكفاح التحصيلي عاملاً مهماً في توجيه سلوك الطلبة، فضلاً عن مساعدتهم في فهم سلوك المحيطين بهم وتفسيره، حيث ان الجامعات العراقية تعتبر مركز حضاري مهم، يقع عليها مسؤولية كبرى في اعداد وتهيئة البيئة الجامعية المناسبة، لتكون بمستوى التحديات من اجل صقل شخصية الطالب الجامعي العراقي من خلال تعزيز قيم تحمل المسؤولية الاجتماعية لديهم.  لكن المشكلة انه ليس جميع الطلبة لديهم قدره على تحمل المسؤولية الاجتماعية، وهذا يترتب عليه عدة أمور سلبية، حيث انه في مثل هذه الحالة نجد ان معظم طلبة الجامعة غير قادرين على تحمل مسؤولية أنفسهم، وبالتالي فانه سيكونون غير قادرين على تحمل مسؤولية عوائلهم عندما يسعون لتكوين الاسرة، وبالتالي غير قادرين على تحمل مسؤولية الاعمال المناطة اليهم. وعليه يهدف البحث الحالي تعرف: الكفاح التحصيلي لدى طلبة الجامعة. وتحمل المسؤولية الاجتماعية لدى طلبة الجامعة. والعلاقة الارتباطية بين الكفاح التحصيلي وتحمل المسؤولية الاجتماعية لدى طلبة الجامعة. وتحقيقا لأهداف البحث قامت الباحثة ببناء مقياس الكفاح التحصيلي، وبناء مقياس تحمل المسؤولية الاجتماعية، وتم تطبيق المقياسين على عينة البحث المكونة من (379) طالب وطالبة، من طلبة جامعة بغداد، علما ان الباحثة قد اتبعت المنهج الوصفي الارتباطي، وبعد جمع البيانات تم استخدام الوسائل الإحصائية التالية من اجل معالجة البيانات منها: الاختبار التائي لعينة واحدة، ومعامل ارتباط بيرسون توصل البحث الحالي الى النتيجة الأتية: ان طلبة الجامعة لديهم كفاح تحصيلي ازاء الظروف الصعبة، وان طلبة الجامعة قادرين على تحمل المسؤولية الاجتماعية، وان هناك علاقة ارتباطية بين الكفاح التحصيلي وتحمل المسؤولية الاجتماعية لدى طلبة الجامعة، وفي ضوء ذلك خرجت الباحثة بعدد من والتوصيات، والمقترحات.
The Geography of Unfreedom
Authors: Eisenberg Ann University of South Carolina School of Law
Published: June 2023

A Review of Coal, Cages, Crisis: The Rise of the Prison Economy in Central Appalachia. By Judah Schept.
СУЩНОСТЬ И ХАРАКТЕРНЫЕ ОСОБЕННОСТИ ИНКЛЮЗИВНОГО ОБРАЗОВАНИЯ
Authors: Ясадова З.А. , Булуева Ш.И.
Published: June 2023

Понятие инклюзии зародилось в условиях масштабных изменений в понимании прав человека, его идентичности. Концепция инклюзии выработалась в результате осмысления ценности человеческого многообразия и отличий между людьми. В инклюзивном обществе среда является тем, что необходимо корректировать, а не человек. В 2015 году ООН приняла новую программу в области устойчивого развития, включающую в себя семнадцать целей, которые необходимо достигнуть к 2030 году. Эти цели призваны обеспечить равенство возможностей. Семь из них имеют прямое отношение к людям с инвалидностью, связаны с предоставлением всеобщего доступа к медицине и образованию. В статье дано определение понятию инклюзивное образование, рассмотрены преимущества инклюзии для детей с ОВЗ, а также выделены ключевые проблемы, препятствующие широкому внедрению инклюзивных практик в образовательную среду России.
ФОЛЬКЛОРНЫЕ ТРАДИЦИИ В ТВОРЧЕСТВЕ С.А. ЕСЕНИНА
Authors: Закриева А.Б. , Ахмадова Т.Х.
Published: June 2023

Тема взаимосвязи литературы с народным поэтическим творчеством – одна из самых значимых в изучении литературы, она рассматривается в творчестве многих писателей. Но нам показалась более интересной и актуальной проблема взаимосвязи творчества Сергея Александровича Есенина с фольклором. Важно отметить, что основной чертой его поэзии является абсолютное единство с простым народом и его жизнью, поэт глубоко чувствовал душу своей Родины, её жизненный уклад, менталитет русского человека. С самого детства он впитывал в себя культуру и быт народа. Без сомнений, Есенин был неразрывно связан с русской природой, с деревней, с народом. А пониманием мы это потому, что поэт очень часто обращается к произведениям фольклора при создании своих работ. В данной статье мы попытались изучить фольклорные традиции в работах Сергея Есенина, проследили и показали на примерах связь русского фольклора с произведениями поэта на основе языка, жанра, ритмического строя, художественных средств и т.д. В этой работе мы показали, какое место занимали различные жанры фольклора в поэзии писателя.
РАЗВИТИЕ УСТНОЙ РЕЧИ МЛАДШИХ ШКОЛЬНИКОВ ВО ВНЕУРОЧНОЙ ДЕЯТЕЛЬНОСТИ
Authors: Джабирова Х.М. , Закраилова Б.Р.
Published: June 2023

В статье подробно изучены теоретические аспекты развития устной речи младших школьников на занятиях по внеклассному чтению. Преимущественно творческий формат таких занятий позволяет педагогу использовать огромное количество игровых и других занимательных методик, которые будут способствовать не только развитию устной речи учеников, но и формированию у них устойчивой любви к чтению. Огромную роль в формировании устной речи у школьника играют не только классные занятия, но и внеурочная деятельность. Пересказ представляет собой оптимальный метод развития устной речи младших школьников на уроках внеклассного чтения. В процессе пересказа у обучающихся формируется способность строить предложения, что положительно влияет на структуру речи, ее выразительность. На занятиях по внеклассному чтению можно использовать современные информационные технологии: мультимедийную презентацию, аудио- и видеоряд, музыкально-литературные композиции, художественные фильмы и мультфильмы по конкретным произведениям. Важной частью внеклассного обучения чтению является контроль над чтением дома. Как правило, после завершения работ по каждому тематическому разделу на дому проводится внеклассное занятие на основе материалов для чтения.