bluuebunny/crossref_metadata_2025 huggingface dataset:
ПРОБЛЕМЫ МОДЕЛИРОВАНИЯ ПРОЦЕССОВ УПРАВЛЕНИЯ ИНФОРМАЦИОННОЙ БЕЗОПАСНОСТЬЮ В АВТОМАТИЗИРОВАННЫХ СИСТЕМАХ
Authors: Г. ВОВИК А
Published: October 2024

Статья посвящена анализу проблем создания численных моделей управления информационной безопасностью автоматизированных систем (ИБ АС) и поиску наиболее эффективных методов моделирования. Проводится анализ существующих методов моделирования, в частности аналитических, статистических и теоретико-множественных. Формируется вывод о нецелесообразности использования аналитических методов ввиду высокого уровня неопределенности переменных модели. В свою очередь, использование статистических представлений ограничено сложностью доказательства репрезентативности выборки, что ставит под сомнение применимость результатов подобных исследований. В результате проведенного анализа, автором предложен комплексный подход к моделированию , объединяющий методы нечеткого моделирования, методы структуризации и методы экспертных оценок. В качестве примера приводятся графические интерпретации возможных решений нечетких моделей уровня угроз в защищаемой системе и уровня показателя защищенности информации, демонстрирующие качественную адекватность такого типа моделей для решения задачи управления ИБ АС. Формализация процесса управления ИБ методами нечеткого моделирования открывает возможность синтеза автоматизированной и, в перспективе, автоматической системы управления ИБ АС.

This article is focused on the analysis of the problems in creating numerical models of information security management of automated systems and on search for the most effective modeling methods. The existing methods analysis of modeling systems, analytical, statistical and set-theoretical ones in particular, is carried out. A conclusion is formed about the inexpediency in using analytical methods because of high level uncertainty of the model variables. In turn the statistical representations use is limited by the complexity of sample representativeness proving, which casts doubts on such studies results applicability. As a result of the analysis, the author proposes an integrated modelling method combining fuzzy modeling methods, structuring methods and expert judgement methods. As an example, graphical interpretations of possible solutions to fuzzy models of the threat level in the protected system and information security indicator level are given, thus demonstrating this type model's qualitative adequacy in solving managing information security problem. The information security management process formalization by fuzzy modeling methods opens up the possibility of synthesizing an automated and, in future, an automatic information security management system.
Irradiation of Bifunctional Masked Ketone Pro-Aromatics Unveils Autocatalytic EDA Complex-Driven Radical Generation
Authors: Chan Cheng-Lin , Tsao Yong-Ting , Paculba Aira Shayne , Lin Pei-Shan , Tsai Zong-Nan , Kunitake Risa , Chiu Ming-Jia , Yeh Chun-Chi , Chiu Cheng-Chau , Liao Hsuan-Hung
Published: October 2024

Pro-aromatic dihydroquinazolinones (DHQZ) are masked ketones capable of group transfer by leveraging their aromatic stabilization energy (ASE) to promote C–C bond cleavage, typically initiated by photocatalysts and transition metals, generating a radical and quinazolinone as a by-product. Here, we present an indirect autocatalytic electron donor-acceptor (EDA) complex mode to enable an initiator-free activation and radical generation for pro-aromatic DHQZ. Mechanistic studies revealed that the aggregation of DHQZ and quinazolinone was enhanced by Zn(OTf)2, while the by-product quinazolinone enabled autocatalysis as an indirect autocatalyst. This strategic design also repurposed the typically discarded redox auxiliary in EDA catalysis into an in-situ generated acceptor. Furthermore, this protocol showcased the versatility of pro-aromatic DHQZ by acting as a 2-in-1 EDA complex precursor by serving as an EDA donor and a latent acceptor through its by-product in generating carbon-centered radicals compatible with various radical traps to access diverse molecular architectures.
Modelación de microrred eléctrica tomando como base un centro integral de reciclaje
Authors: Arias Barragán Luis Alejandro , Aparicio Gallo Andrea , Fernando Rico Luis , Laverde Soranji , Cubides Laura Alejandra , Molina Eyleen Valentina
Published: October 2024

En el presente proyecto se propone realizar el monitoreo, control y automatización del proceso de generación de energía eléctrica en una microrred, tomando como recurso energético la biomasa obtenida de centros integrales de reciclaje y apoyada con fuentes alternativas de energía. El proyecto se plantea desarrollar en las afueras de ciudades intermedias de Colombia en asocio con empresas de servicios públicos dedicadas a la limpieza de áreas públicas, la recolección y transporte de desechos sólidos urbanos, y la disposición final de residuos. En los centros integrales de reciclaje se estima que un 44% del volumen recolectado corresponde a materia orgánica. Para el aprovechamiento de esta materia orgánica en el proceso de obtención de biogás se ha modelado el uso de biodigestores tipo TAIWAN, los cuales serán monitoreados y controlados tanto in situ como de manera remota. El biogas obtenido es utilizado para alimentar una caldera de vapor con ciclo combinado y de manera paralela alimenta una microturbina de tipo CAPSTONE. La caldera producirá vapor sobrecalentado para alimentar una turbina mediante ciclo Rankine con tomas parciales de vapor a fin de mejorar la eficiencia del proceso. Para las primeras tomas del ciclo termodinámico se ha considerado incluir agua precalentada mediante el uso de colectores solares y de la microturbina CAPSTONE. La turbina de vapor se conectará a un grupo generador para la obtención de un mínimo de 30 kVA para una frecuencia de 60 Hertz. Las fuentes alternativas de energía como solar y eólica son utilizadas en la microrred para soportar la alimentación de sistemas de control y subsanar algunos picos de demanda que puedan llegar a requerirse hacia la microrred. Para el proyecto se ha planteado monitorear la tensión de salida trifásica del generador, así como su frecuencia, ángulo de excitatriz, potencia activa, reactiva y aparente. El monitoreo se realizará inicialmente in situ, pero para la etapa posterior a la puesta en marcha se ha contemplado una control y automatización de procesos a distancia a través de aplicaciones web.
Reservation Wages Revisited: Empirics with the Canonical Model
Authors: Davis Steven J. , Krolikowski Pawel M.
Published: October 2024

Using innovative longitudinal data from a survey of unemployment insurance (UI) recipients, we test several implications of a canonical job search model for reservation wages during unemployment spells. First, consistent with the model, we find that reservation wages fall faster when UI benefit durations are shorter. However, workers set their initial reservation wages higher, and adjust them slower, relative to model predictions. Second, workers' expectations—elicited at the beginning of their unemployment spell—about how their reservation wage will evolve if they remain unemployed are largely congruent with reservation wage realizations, as assumed in the canonical model. Third, our data on expectations and realizations suggest that dynamic selection over the unemployment spell is inconsequential for our results. Fourth, higher wages on workers' lost jobs, relative to predictions from a Mincerian wage regression, hasten the expected and realized declines in reservation wages over the unemployment spell. Finally, reservation wages are a more powerful predictor of re-employment wages than wages on the previous job.
Impact of Information and System Quality on User Satisfaction with Outpatient EMRs at RSKIA Sadewa, Indonesia
Authors: Putri Dela Astia , Sutrisno Trismianto Asmo
Published: October 2024

The use of electronic medical records (EMR) in outpatient services continues to increase, however, many hospitals still face challenges in ensuring optimal adoption and user satisfaction. Previous research suggests that issues related to information quality and system stability may hinder the effective use of EMRs, but not many studies have specifically analyzed these two factors in the context of regional hospitals. This study aimed to evaluate the effect of information and system quality on EMR user satisfaction in RSKIA Sadewa, Yogyakarta, and identify strategic improvement steps. Primary data were collected from 42 questionnaires distributed to EMR users, and 37 responses were analyzed using multiple linear regression. Results showed that system quality (β = 0.213, p < 0.05) and information quality (β = 0.199, p < 0.05) had a significant influence on user satisfaction, with a joint contribution of 81.1% (R² = 0.811). Although the system provided sufficient features, system reliability constraints and incomplete information negatively affected user experience. System menu optimization and regular training are proposed as strategic measures to improve operational effectiveness. The findings provide important insights for hospital managers and policymakers regarding the importance of strengthening IT infrastructure and data validation to support more effective EMR implementation. Further research is recommended to involve various hospitals in different contexts to expand external validity and provide more comprehensive recommendations for the healthcare sector.
العقاب
Authors: Canton Rob
Published: October 2024

يعد الوصول إلى مجتمع آمن من أهم مقاصد سياسات العقاب في المجتمعات على مر العصور. يعرض هذا الكتاب سرداً علمياً لمفاهيم العقاب ونظرياته والأثار الاجتماعية والنفسية المترتبة على تطبيقه ليس من وجهة النظر القانونية فقط ولكن من وجهة نظر المجتمع والشخص المعاقب ذاته. وأهم ما يميز هذا السرد هو السلاسة وربط النظريات بأمثلة حياتية ونماذج من الأعمال الدرامية والسينمائية الشهيرة مما يقربها للقارئ بحيث تتعدى كونها نظريات في علم الجريمة وتساعد القارئ على فهم أبعاد تطبيق العقوبة في المجتمعات الحديثة. قدم الكاتب كل ذلك في أسلوب سلس يتميز بالبساطة وقد حرصت المترجمة على تقديم الكتاب بنفس سلاسة الأسلوب بالعربية. إلى قارئ العربية المحترم.
الجريمة والعدالة على الصعيد الدولي وعبر الحدود الوطنية
Authors: Natarajan Mangai ,   Naif Arab University for Security Science
Published: October 2024

تجتذب دراسات الجريمة والعدالة الجنائية دارسين وباحثين ينتسبون إلى طائفة متنوعة من التخصصات بسبب طبيعة مجالهما البيني؛ فهي تعتمد على كثير من التخصصات الأخرى في تطوير النظريات حول الجريمة والإجرام وعملية العدالة الجنائية. وتشمل تلك التخصصات: الاقتصاد، والقانون، والجغرافيا البشرية، وعلم الاجتماع، وعلم النفس، والدراسات الإصلاحية، والإدارة العامة، وعلوم الشرطة، والعمل الاجتماعي. يقدم هذا الكتاب طبيعة الجرائم الدولية وعبر الوطنية، والأسس النظرية لفهم العلاقة بين التغيير الاجتماعي وتضاؤل فرص الجريمة، والعولمة، والهجرة، والصراعات الثقافية، والأطر القانونية الناشئة للوقاية منها ومكافحتها. ويوفر هذا الكتاب للقارئ مقدمة واسعة النطاق للقضايا الدولية الرئيسة في الجريمة الدولية وعبر الوطنية وطرق وأساليب الوقاية منها، ويغطي جميع النظريات الأساسية في هذين المجالين، كما يشرح بوضوح صلتهما بالعالم اليوم. ويتناول الكتاب مجموعة من الموضوعات المتنوعة تشمل، على سبيل المثال لا الحصر: الاتجار غير المشروع في أشكاله المختلفة، وشبكات الجريمة، والجرائم المتعلقة بالأطفال، والجريمة المنظمة والإرهاب، والجريمة البيئية، والجريمة الإلكترونية، وجرائم العملات وغسل الأموال، وجرائم الفساد، وجرائم العنف والإبادة، ونماذج الشرطة والتحقيق والسجون وفلسفة العقاب، إلى جانب تناول كثير من دراسات الحالات والأمثلة من جميع أنحاء العالم، كما يستعرض التحديات التي ينطوي عليها تحقيق العدالة وجهود التعاون الدولي للحد من الجرائم الدولية وعبر الوطنية والكشف عنها والتصدي لها. ويجمع الكتاب بين المعرفة النظرية والخبرات العملية في آن، ويقدم في الوقت المناسب تحليلًا لموضوع معقد يتعلق بالجريمة والعدالة الدوليتين. ويُعتبر الكتاب من أهم الدراسات القيّمة التي تُفيد الطلاب والدارسين والعلماء وواضعي السياسات ومناصري العدالة الساعين إلى تحقيقها لملايين الضحايا على الصعيد الدولي وعبر الحدود.
VITAMIN D3: DETAILED CHARACTERIZATION OF THE SUBSTANCE AND ANALYSIS
Authors: E.B. Sysuev , E.F. Stepanova , V.D. Noskova
Published: October 2024

The article examines in detail the issues of standardization of the obtained vitamin D substance using its own original technological scheme, and the possibility of further use of the substance to create a standard sample (SS).
The work traces the current problem associated with the lack of production of domestic vitamin D substance.
The object of study is the vitamin D substance isolated from natural raw materials. To assess the quality of the obtained substance, quantitative and qualitative determination methods, high-performance liquid chromatography (HPLC) at a wavelength of 265 nm, IR spectroscopy in the emission range of the spectrum from 4000 cm-1 to 400 cm-1, organoleptic method, polarimetry, refractometry and other methods of analysis were used.
The obtained vitamin D substance, according to its quality characteristics, can be confidently used not only as a material for the manufacture of SS, but also as a starting substance in the pharmaceutical, food and agricultural sectors of the national economy.
HARRINGTON DESIRABILITY FUNCTION FOR ASSESSING THE OPTIMAL COMPOSITION OF NAPHTHOQUINONE COMPLEX FILMS AND GEL
Authors: L.M. Zakharevich , A.Ya. Basharov , N.V. Matyushchenko
Published: October 2024

When a new pharmaceutical product development comes to the stage of selecting the optimal combination of components, researchers often need a comprehensive assessment method for experimental samples. The difficulty is caused by overall complexity of choosing the correct qualitative and quantitative parameters expressed in different units of measurement and establishing priorities between the criteria for the combined assessment. In this case membership functions can help, for example the generalized Harrington desirability function, which allows to combine individual indicators that differ in value and dimension. The article provides examples of the practical application of the generalized Harrington desirability function in assessing several parameters of experimental samples of films and gel developed by us with a naphthoquinone complex of Lithospermum erythrorhizon in order to determine the best composition of these forms. The chosen method made it possible to calculate the generalized desirability for each experimental sample, taking into account all the studied criteria and to determine the most successful experimental samples for further work.
THE RELATIONSHIP BETWEEN SOCIO-PSYCHOLOGICAL AND ORGANIZATIONAL ASPECTS OF THE CORPORATE CULTURE OF A PHARMACEUTICAL MANUFACTURING COMPANY
Authors: M.S. Balabanov , Zh.S. Safronova
Published: October 2024

In the context of the risks of business process transformation and digitalization of production, an important aspect is the search and implementation of new approaches to the company's human resource management system. The purpose of this study is to describe the results of a study of the relationship between the socio-psychological and organizational aspects of the corporate culture of a pharmaceutical manufacturing company and their management capabilities. The main research methods used are: system analysis, survey-questionnaire, rating-scaling and expert assessments. Factors such as the socio-psychological climate in the team and the development of sports activities in a pharmaceutical company are considered. It is shown that these aspects play an important role in strengthening corporate culture and increasing employee motivation. Taking into account socio-psychological and organizational factors in activities contributes to achieving the common goals of the employee and the employer, maintaining values that affect the level of the company's reputation. Conclusions are drawn about the need to take into account the interrelationship of socio-psychological and organizational aspects necessary for effective management of the corporate culture of a particular pharmaceutical company.
REGIONAL MONITORING OF RISK FACTORS FOR CHRONIC NON-COMMUNICABLE DISEASES AFTER COVID-19
Authors: N.D. Chereshneva , T.F. Chernykh
Published: October 2024

Annotation. Chronic non-communicable diseases (NCD) represent a major public health problem in recent decades. NCD kill 41 million people annually, accounting for 74% of all deaths worldwide. WHO predicts that the total number of deaths from NCD will rise to 55 million by 2030 unless drastic measures are taken. Cardiovascular disease, cancer, chronic respiratory disease and diabetes are the four leading causes of premature mortality among NCD. Multimorbidity affects 65% of people over 65 years of age, requiring more patient-centred and complex models of care. The aim of the study was to conduct regional monitoring of risk factors for chronic noncommunicable diseases in geriatric patients. Outpatient charts of 152 patients aged 60 years and older who had undergone COVID-9 and had undergone an in-depth adult check-up were used for the study. The average age of the patients who underwent the dispensary was 70.0±5.7 years. Questionnaire survey of 152 patients aged 65 years and older to identify NCD and senile asthenia showed that the highest proportion of patients had risk factors for cardiovascular diseases - 63.2%, osteoporosis - 40.8%, GI diseases - 28%, senile asthenia - 27% and polypragmasia - 20.4%. 32.2% of respondents noted a decrease in memory, perception of material, impaired comprehension, loss of ability to distribute time, 30.9% experienced a decrease in mood, loss of energy, depressive state, 24.3% each experienced vision and hearing problems that impair the quality of life, and 22.4% of persons over 65 experienced difficulty in walking. Based on the results of the study, data collection modules based on the STEPS system were identified for the step-by-step assessment of risk factors for the development of chronic non-communicable diseases, and a model for a comprehensive approach to improving the health of citizens aged 60 years and older, who have the highest risk of developing NCD, was proposed.
TECHNOLOGY OF NANOCAPSULES FOR DRUG DELIVERY
Authors: T.S. Gutnova , D.V. Kompancev , E.A. Teunova
Published: October 2024

Encapsulation of active ingredients in solid capsules made of biodegradable materials has attracted considerable attention over the past decades. In this brief review, we focus on the preparation of micro- and nanosized capsules and emulsions based on artificial peptides as a fully degradable material. It discusses various approaches to the preparation of polymer-based capsules as well as their critical properties such as size and stability. Dispersed polymer nanocapsules can serve as nanosized drug carriers to achieve controlled release as well as effective drug administration. The stability of the dispersion is determined by the type of surfactant and the nature of the outer shell of the capsule. Their release and degradation properties largely depend on the composition and structure of the capsule walls. Another important criterion is the capsule size, where the optimum is usually observed in the radius range of 100 to 500 nm. Nanocapsules can be prepared in fundamentally different ways: nanoprecipitation, emulsion diffusion, double emulsification, emulsion coacervation, polymer coating and layer-by-layer, and depend on the methodological and mechanistic aspects, encapsulation of the active substance and the raw materials used. Nanocapsules made using various biodegradable polymers are attracting increasing attention and are considered as one of the most promising drug delivery systems. Nanoencapsulated systems have a relatively higher intracellular absorption compared to microparticles, which can be modified depending on the surface charges of the nanocapsules and the hydrophilic or hydrophobic nature of the polymer used to form the shell.
ANALYSIS OF PRACTICAL ASPECTS OF IMPROVEMENT OF PROFESSIONAL COMPETENCE OF PHARMACISTS IN THE FIELD OF INTERACTION WITH LOW-MOBILITY VISITORS OF PHARMACIES WITH DISABILITIES
Authors: A.R. Ishkinina , A.Kh. Gaisarov , V.A. Kataev
Published: October 2024

Currently, pharmacies are part of the healthcare system and must comply with the requirements for providing an accessible environment for people with disabilities, including providing them with the opportunity to receive the necessary pharmaceutical services. The aim of the study is to analyze the practical aspects of improving the professional competence of pharmacists in the field of interaction with people with limited mobility and disabilities in pharmacies. The texts of regulatory legal acts of the Russian Federation and also systemic and logical methods of their interpretation have been used in this study. It has been revealed that the current federal state educational standards of higher education and secondary vocational education in the specialty «Pharmacy» do not directly provide for the need to train future pharmacists in the basics of professional interaction with people with disabilities, but they establish the possibility of introducing additional competencies and/or new academic disciplines into the curricula for more in-depth training of graduates. It has been shown that pharmacists are required to have knowledge of the anatomical and functional characteristics of various groups of people with limited mobility and disabilities, their physiological states and pathological processes that directly affect their ability to receive pharmaceutical services in pharmacies. The possibility of pharmacists of pharmacies to consult people with limited mobility and disabilities on the necessary pharmacy goods online has been analyzed, taking into account possible functional disorders in these people – in various formats: text, audio only or using video communication. It has been proposed to introduce training on relevant aspects of their professional interaction with visitors to pharmacies with disabilities into educational programs for training and professional development of pharmacists.
ANALYSIS OF SALES OF COMBINED DRUGS FOR SYMPTOMATIC TREATMENT OF ACUTE RESPIRATORY VIRAL INFECTIONS AND DEVELOPMENT OF ANTIGRIPPIN ASSORTMENT ON THE EXAMPLE OF KAZAN PHARMACY
Authors: S.A. Sidullina , I.K. Tukhbatullina , A.A. Khaidarova
Published: October 2024

There is strong competition between pharmacy providers. The abundance of advertising allows the public to be relatively informed in the variety of medicines offered by suppliers. All of the above, including high rent for inventory storage space, emphasizes the problem of the need for rational assortment formation. Only a properly created assortment of goods will allow the pharmacy to compete in the eyes of consumers, not to lose regular customers and to acquire new ones. With effective management of the product assortment can increase the income of the pharmacy due to the lack of unsatisfied demand. It is also possible to reduce the number of sales lost due to lack of goods, to accelerate the turnover of goods, to reduce the cost of storing medicines. Currently, there is a variety of combination medicines offered by suppliers to combat several symptoms of acute respiratory viral infections. The article presents the results of ABC-analysis, XYZ-analysis and their combination on the example of the assortment of dosage forms of antigrippin of the pharmacy of the state network of the city of Kazan. The distribution of antigrippin assortment into groups is shown and recommendations on the strategy of the pharmacy manager in relation to each of the groups are offered. The fact that these are seasonally consumed commodities with medium forecasting capabilities makes it difficult to plan the procurement of combination medicines to control several symptoms of acute respiratory viral infections. After combining the results of ABC XYZ analysis, it was found that antigrippin pharmacy-made antigrippin and antigrippin effervescent tablets are commodity items with a low share of turnover and number of sales units. They showed a medium degree of forecast reliability due to unstable demand. Antigrippin express powder, antigrippin - ANVI capsules and Vicks Antigripp Max powder made up the majority of the assortment, a small share of the turnover of antigrippin dosage forms and the number of sales units. These products showed low forecast reliability due to non-constant demand and generated little profit. This could be due to the fact that the consumer did not have sufficient information about these products.
MARKETING ANALYSIS OF THE RANGE OF BASIC SINGLE-COMPONENT MEDICINES USED FOR THE TREATMENT OF SLEEP DISORDERS
Authors: A.A. Soltangishieva , N.M. Bat
Published: October 2024

In recent years, many studies have noted that the number of occurrence of various sleep disorders is increasing among the population, while such problems as self-medication, untimely access to a doctor, the presence of concomitant diseases, the development of acute forms of disorders into chronic ones are highlighted, all this affects the quality and life expectancy of the population and makes it relevant to study pharmacotherapy of drugs for the treatment of these disorders in the field of pharmaceutical care [1-6; 11]. The purpose of the study was to establish a list and conduct a marketing analysis of the assortment of the main groups of monopreparations used for the treatment of sleep disorders presented on the domestic pharmaceutical market for their subsequent use in more extensive comprehensive marketing research in the context of sleep disorder therapy. The materials for the study were data from the State Register of Medicines and regulatory documents reflecting the attitude of objects to accounting and control of their sale on the market. The following methods were used: comparisons, systematization, grouping, statistics, as well as structural and assortment analyses. The article presents the results of a study of the Russian market of monopreparations of this orientation. The systematization of the main monopreparations was carried out, as a result, 7 groups were identified, which include 25 international nonproprietary names of medicines represented by 78 trade names, the proportion of manufactured drugs within each group and relative to the total number of trade names were calculated. The next step was to analyze the conditions for the release of drugs, their inclusion in lists reflecting accounting and control during implementation in accordance with regulatory documentation. In conclusion, it is noted that the obtained ranking data and the corresponding calculations will serve as a basis for further research in the field of the pharmaceutical market of drugs used for sleep disorders.
ANALYSIS OF THE QUALITY OF POLYMERIZATION OF BASE PLASTICS
Authors: A.A. Komova , M.V. Artemov , E.G. Borisova , V.A. Zheleznyak , A.V. Potockaya , M.K. Fedichkina
Published: October 2024

The issue of restoring dental defects is relevant for modern dentistry. Restoration of the functions of the dental system is possible by partial or complete removable laminar dentures which basis is made of lamellar plastics in the most cases. It is necessary to strictly observe the temperature regime of polymerization of plastics, since structural defects in the material can form, causing complications after prosthetics. There are devices for automatic polymerization with a temperature control function, but the most common is the classical method (in a water bath) of making denture bases. Purpose of the study: compare the quality of polymerization of base plastics using the classical method and using modern equipment. Materials and methods: 8 plastic samples were made, 50% of which were polymerized using the classical method, and the other half using an apparatus for hot polymerization of plastic. An external inspection of the samples was carried out and the finishing time of the plates was estimated. After polishing, the samples were examined using an electron microscope. Results and discussion: samples, polymerized using the classical method showed signs of granular porosity, the polishing time was 8 minutes 13 seconds; electron microscopy results revealed the presence of defects, which could lead to complications. Plates polymerized by the instrumental method are homogeneous, polishing time is on average 4 minutes 42 seconds. When these plates were examined with an electron microscope, there were minor defects. Conclusion: it is recommended to polymerize base plastics using devices for hot polymerization of plastics in order to prevent complications from using removable dentures.
INNOVATIVE METHODS OF DIAGNOSIS OF BRUXISM IN MODERN DENTISTRY
Authors: A.V. Mashkov , A.V. Zhidovinov , P.A. Ponomarev
Published: October 2024

The article is devoted to one of the most important problems in modern dentistry – bruxism. The relevance is associated with an increase in the prevalence of bruxism in patients of different age groups. The article discusses etiological factors, clinical manifestations and various diagnostic methods for patients with bruxism. The material of the review is the long-term research of domestic and foreign scientists devoted to the etiology and modern diagnosis of patients with bruxism. Using the Elibrary search engine, 17 articles were selected for the time period from 2003 to 2023. The article uses a descriptive method that allowed us to consider the current state of the problem and outline ways to further solve it. The main content of the study is the analysis of innovative methods for the diagnosis of bruxism, which make it possible to diagnose pathology at the initial stage of the disease and start its treatment in a timely manner. The article emphasizes the need to supplement existing clinical recommendations with innovative methods and diagnostic tools for this pathology. As a result of the analysis of the literature, the authors developed a systematization of all methods of diagnosing bruxism by the subject of the study. The article discusses research aimed at studying the occlusal relationship of the jaws, the diagnosis of a psychopathological condition, the diagnosis of musculoskeletal dysfunction, the diagnosis of neurotransmitter imbalance and the detection of diseases of the musculoskeletal system. The authors concluded that with the advent and introduction of computer technologies into dental practice, innovative methods and tools for diagnosing bruxism were developed, which led to a significant improvement in the quality of dental care provided. Special attention is paid in the article to the importance of the principle of primacy and an interdisciplinary approach in conducting diagnostic studies aimed at identifying bruxism.
MODERN TREATMENT OF SCAR DEFORMATION OF TISSUE
Authors: P.G. Kogan , K.I. Khorak , D.G. Parfeev , A.M. Morozov , V.O. Bogdanova , S.D. Vasileva
Published: October 2024

The problem of scar treatment is one of the most widespread in modern medicine. Treatment of scar formations is one of the most difficult tasks, as there is no single standard that is favorable in terms of efficacy and safety despite the active development in this area of research. Currently, conservative methods of treatment of scar tissue deformities such as corticosteroid administration, botulinum therapy, cryotherapy, microneedling, as well as surgical excision in combination with therapeutic methods are widely used, due to which the most favorable result is achieved. This study is devoted to the study of various modern methods of correction of hypertrophic and keloid scars that are becoming widespread in medicine, their comparison and identification of important advantages and disadvantages in order to choose the most effective treatment technique. Currently used conservative methods of treatment allow to cope with the problem of scar formations, but due to the high incidence of side effects, there is a tendency to search for the combined use of each of them, including with surgical excision to prevent the development of recurrences and to achieve a pronounced cosmetic effect and satisfaction among patients. Thanks to the constant development of medicine and the improvement of various methods, each patient can receive a personalized treatment approach that is guaranteed to reduce aesthetic discomfort due to the existing pathology, which is the main and important aspect of scar correction.
THE RELATIONSHIP OF THICKENING OF THE ARCH OF THE FOOT AND THE DEVELOPMENT OF THE CENTRAL NERVOUS SYSTEM IN CHILDREN. (LITERATURE REVIEW)
Authors: Yu.V. Vladimirova , L.I. Mazur , V.A. Zhirnov , I.L. Shadrina
Published: October 2024

Today, the World Health Organization believes that musculoskeletal disorders in children occupy a leading position. According to statistics provided by Russian orthopedists over the past year, 24.2 - 67.3% of schoolchildren, depending on the region, have longitudinal or transverse flat feet. The second most common disorder in children is developmental disorders in the field of intellectual activity. Motor activity is a natural need for people to move. Intellectual development is understood as a set of various cognitive functions of an individual in society: from thinking, as well as perception, to the imagination and thinking of a person. Therefore, studying the relationship between the musculoskeletal and nervous systems in children is an important task of our time. The purpose of our study was to assess the relationship between thickening of the arch of the foot and the development of the central nervous system in children, through the prism of scientific works of orthopedists, pediatricians, neurologists and psychologists. Our review of the literature proves the importance of studying this problem and the need for a clinical study. To improve diagnostics, it is necessary to create a combined universal assessment system that will allow comparing results and conducting a mathematical analysis of the initial state of the musculoskeletal system and intellectual level in children, as well as to analyze changes in the course of therapy. Also, in our opinion, it is necessary to develop a set of exercises for therapeutic physical training that will not only strengthen muscles, form the arches of the feet, but also simultaneously train the frontal lobes of the brain, which will enhance concentration and develop memory. Therefore, we consider it necessary to expand the range and conduct extensive studies with a large sample size.
IMPACT OF DIGITAL TECHNOLOGIES ON MEDICAL EDUCATION: SOCIOLOGICAL ASPECTS AND INFLUENCE ON HEALTHCARE
Authors: T. V. Kolesova , L. N. Denisenko , S.P. Derevyanchenko , E.V. Manuylova
Published: October 2024

This article is dedicated to the study of the impact of digital technologies on the educational process in medical universities, with a focus on sociological aspects and their significance for the healthcare system. It examines how the use of digital tools and platforms changes students' approaches to studying medicine and shapes their perception of the role of technology in improving the quality of medical services and ensuring public health. The informational and educational environment transforms traditional teaching methods, providing new opportunities for updating curricula and creating conditions for the rapid exchange of information between students and educators.
Digitalization of the educational process implies a change in the roles of all participants in the educational process. Students become researchers actively using information and communication technologies to acquire knowledge and practical skills. At the same time, educators assume the role of mentors, supporting students in their learning and possessing the necessary competencies in digital technologies. The article analyzes the most effective tools for facilitating interaction in the educational environment, such as virtual boards like Google Jamboard, Miro, and Padlet, which contribute to the development of critical thinking and presentation skills among students. Additionally, the article addresses the challenges faced by medical universities in the process of integrating digital technologies. Effective implementation of digitalization requires strategic planning and a comprehensive approach to updating educational programs, which will create a sustainable platform for the future professional growth of students.
In conclusion, the authors emphasize that digital technologies, along with innovative teaching methods, significantly enhance the quality of education in medical universities. This, in turn, contributes to the training of highly qualified specialists capable of effectively working in modern healthcare conditions, ultimately having a positive impact on public health and the organization of healthcare as a whole.
Evaluación del nivel de ruido y su efecto en los trabajadores del taller de mantenimiento y producción de la Universidad Nacional del Altiplano, Puno
Authors: Sonco Justo Fanny Marisol
Published: October 2024

Noise generated by activities in maintenance and production workshops can cause damage to the hearing system. This research aimed to determine noise levels and their effects on maintenance and production workshop workers during 2018 and 2019. A quantitative, non-experimental and descriptive approach was used. The workshop has four areas dedicated to metalworking, carpentry and melamine. Noise measurements were made in each area and in existing equipment, using a sound level meter in accordance with ISO 1996-Part 1:1986 and IEC 61672-1:2002. For monitoring, the National Noise Monitoring Protocol (D.S. No. 223) and the methodology of the Regulations on Occupational Safety and Health in Mining (D.S. No. 024-2016-EM) were applied. The results showed noise levels of 78.1 dB, 80.8 dB, 78.2 dB, and 78.0 dB in areas PR-1, PR-2, PR-3, and PR-4, respectively, of which only PR-2 exceeded the standard of 80 dB for industrial zones. The evaluation of 27 devices revealed that 93% exceeded 80 dB, reaching up to 107.9 dB. These data indicate a high risk of hearing problems for staff, underscoring the need to monitor exposure time and conduct regular assessments to minimize long-term effects.
Evaluación de concentración de arsénico para proponer la alternativa de remediación en el río Ananea
Authors: Vargas Quea Marcelino
Published: October 2024

This study addresses the problem of arsenic contamination of water from the Ananea River due to artisanal and informal mining. The main objective is to evaluate arsenic contamination of waters of the Ananea River and remediation alternatives, during the 12 months of 2018 to 2019. The results reveal that the concentration of arsenic in water at point P-A located in the Sillacunca lagoon was 0.926 mg/l, 0.527 mg/l, 0.730 mg/l; in sediments 117.475 mg/kg, 74.8 mg/kg, 92.50 mg/kg; at the point of monitoring P-B located in the Ananea River 100 meters upstream confluence with the Lunar de Oro River, the concentration of arsenic in water is 0.422 mg/l, 0.221 mg/l, 0.225 mg/l; in sediments it is 56.73 mg/kg, 26.77 mg/kg, 62.5 mg/kg. The concentration of arsenic in the area of the Sillacunca lagoon and in the area in the Ananea river 100 meters upstream confluence with the Lunar de Oro river presented a higher concentration.
KOLONIALISME DALAM NOVEL RASINA KARYA IKSAKA BANU
Authors: Annisa Zuraida Jihan , Maharani Umaya Nazla , Septiana Ika
Published: October 2024

Artikel ini mendeskripsikan kolonialisme dalam novel Rasina karya Iksaka Banu. Melalui novel, kolonialisme dapat kembali dikenang dan memberikan banyak informasi. Buku yang menceritakan kolonialisme bukan hanya pada buku terbitan beberapa tahun setelah peristiwa kolonialisme. Novel Rasina karya Iksaka Banu terbitan tahun 2023 juga menceritakan peristiwa masa kolonial. Aspek kolonial dalam penelitian ini adalah penggunaan nama daerah dan tempat umum yang digunakan dalam novel dan menunjukkan jika peristiwa tersebut terjadi pada masa kolonial. Penelitian diselesaikan menggunakan teknik studi pustaka dan baca catat. Dan hasil perolehan data dideskripsikan menggunakan metode kualitatif. Hasil dari penelitian ditemukan beberapa nama daerah dan beberapa tempat yang digunakan pada masa kolonial dalam novel. Selain itu juga ditemukan beberapa perbedaan perlakuan antar probumi dan orang Belanda yang menguatkan jika latar cerita dalam novel terjadi pada masa penjajahan atau kolonial.
Pendidikan Karakter Berperspektif Kebudayaan dalam Cerita Dongeng
Authors: Andrian Setia Naka , Nayla Azzah , Fatimah Siti
Published: October 2024

Cerita dongeng dinilai sebagai salah satu upaya yang dapat dilakukan sejak dini untuk menawarkan nilai-nilai pendidikan karakter bagi siswa. Cerita dongeng juga dapat mempermudah para siswa dalam memahami segala informasi yang diperoleh dalam kehidupan sehari-hari. Oleh karena, kisah-kisah yang disampaikan dalam cerita dongeng setidaknya perlu diberikan tawaran yang lebih menarik dan interaktif agar siswa tertarik untuk mendengarkan cerita dongeng. Dalam penelitian ini berupaya mendeskripsikan bagaimana penanaman pendidikan karakter melalui cerita dongeng bagi siswa SDN 3 Kedung Jepara. Penelitian ini menggunakan pendekatan deskriptif kualitatif. Penelitian deskriptif kualitatif ini dilakukan melalui angket dan penanaman pendidikan karakter melalui cerita dongeng bagi siswa SDN 3 Kedung Jepara. Dari uraian pembahasan yang telah dipaparkan dapat disimpulkan bahwa penanaman pendidikan karakter melalui cerita dongeng bagi siswa SDN 3 Kedung Jepara yang paling dominan dilakukan melalui dongeng-dongeng yang diangkat pada penanaman karakter agama dan sikap tolong-menolong. Hal tersebut juga menunjukkan bahwa sekolah tersebut berada di wilayah yang termasuk dalam daerah di dekat pesisir. Kebudayaan masyarakat pesisir pun turut serta mewarnai cerita dongeng yang ditanamkan kepada para siswa.
Kekerasan terhadap Perempuan dalam Novel Nyutrayu karya Joko Gesang Santoso
Authors: Suyono Zahrotul Mawaddah , Harjito  , Septiana Ika
Published: October 2024

Tujuan dalam penelitian ini adalah untuk mendeskripsikan bentuk kekerasan terhadap perempuan dalam novel Nyutrayu karya Joko Gesang Santoso. Metode penelitian dalam penelitian adalah dengan menggunakan metode deskriptif kualitatif. Teknik pengumpulan data dalam penelitian ini dengan menggunakan teknik simak catat. Instrumen yang digunakan dalam pengumpulan data. yaitu menggunakan kartu data.Hasil penelitian menunjukkan bahwa adanya bentuk-bentuk kekerasan terhadap perempuan yang mengalami kekerasan seperti kekerasan fisik, seksual, psikologis, struktural dan pelecehan seksual akibat dari kekuasaan yang patriarki. Tokoh perempuan yang mengalami kekerasan dalam novel Nyutrayu, yaitu Aran, Seorang Gadis, Perempuan yang dijual sebagai pekerja seks, Sina, Sawit, dan Lara yang dapat dilihat dari tingkah laku tokoh, dialog tokoh, penggambaran tokoh melalui tokoh lain, pikiran tokoh, dialog tokoh lain dan dialog antartokoh. Tokoh-tokoh perempuan tersebut seperti tidak memiliki kedudukan sehingga terus mengalami kekerasan dan dianggap tidak penting. Kekerasan yang dialami perempuan menyebabkan perempuan mengalami trauma, membenci laki-laki, mencoba bunuh diri, membiarkan diri dianiaya, menyerahkan diri diperkosa secara paksa, memilih hidup seorang diri, dan mencongkel kedua mata agar tidak dapat melihat masa depan dan masa lalu.
Topology for discrete mathematics
Authors: Ershov Yu. L.
Published: October 2024

A series of results is presented on the problem of the existence and the uniqueness of extensions of continuous mappings on topological spaces.
A Learn-to-Rank Approach to Medicine Selection for Patient Treatments
Authors: Sami Farouqa Maher , Azzeh Mohammad
Published: October 2024

Aim/Purpose: This research utilized a learn-to-rank algorithm to provide medical recommendations to prescribers. The algorithm has been utilized in other domains, such as information retrieval and recommender systems.

Background: Ranking the possible medical treatments according to diagnoses of the medical cases is very beneficial for doctors, especially during the coding process.

Methodology: We developed two deep learning pointwise learn-to-rank models within one prediction pipeline: one for predicting the top possible active ingredients from disease features, the other for ranking actual medicines codes from diseases and the ingredients features.

Contribution: A new learn-to-rank deep learning model has been developed to rank medical procedures based on datasets collected from insurance companies.

Findings: We ran 18 cross-validation trials on a confidential dataset from an insurance company. We obtained an average normalized discounted cumulative gain (NDCG@8) of 74% with a 5% standard deviation as a result of all 18 experiments. Our approach outperformed a known approach used in the information retrieval domain in which data is represented in LibSVM format. Then, we ran the same trials using three learn-to-rank models – pointwise, pairwise, and listwise – which yielded average NDCG@8 of 71%, 72%, and 72%, respectively.

Recommendations for Practitioners: The proposed model provides an insightful approach to helping to manage the patient’s treatment process.

Recommendation for Researchers: This research lays the groundwork for exploring various applications of data science techniques and machine learning algorithms in the medical field. Future studies should focus on the significant potential of learn-to-rank algorithms across different medical domains, including their use in cost-effectiveness models. Emphasizing these algorithms could enhance decision-making processes and optimize resource allocation in healthcare settings.

Impact on Society: This will help insurance companies and end users reduce the cost associated with patient treatment. It also helps doctors to choose the best procedure and medicines for their patients.

Future Research: Future research is required to investigate the impact of medicine data at a granular level.
MİLLİ KÜTÜPHANE 8121 NUMARADA KAYITLI BİR GAZEL MECMÛASINDA YER ALAN ARZÎ DEDE’YE AİT BEŞ GAZEL VE BU GAZELLERİN İNCELENMESİ
Authors: Beklen Sadık
Published: October 2024

Mecmualar, edebiyat tarihimizde yer edinmiş şairlerin şiirlerini ortaya çıkarmak açısından başvurulan önemli kaynaklar arasında yer almaktadır. Bu eserlerde bilinen şairlere ait yeni şiirler olabileceği gibi adı bilinmeyen şair ve onların şiirlerine rastlamak mümkündür.
Çalışmada Milli Kütüphane 8121 numarada kayıtlı Mecmua-i Gazeliyyât adlı şiir mecmuasında yer alan Arzî Dede mahlaslı bir şaire ait beş gazele yer verilecek ve bu gazeller şekil ve muhteva yönünden incelenecektir.
Yapılan araştırmalar neticesinde söz konusu gazellerden ikisinin başka herhangi bir çalışmaya konu olmadığı tespit edildi. Bununla birlikte kaynaklarda Arzî mahlası kullanan yalnızca bir şair tespit edildi. Mecmuada yer alan şiirlerin bu şaire ait olup olamadığına dair elimizde herhangi somut bir delil olmasa da bu mahlasta şiir yazan başka şairin kaynaklarda adının geçmemesi şiirlerin Arzî Dede mahlaslı bu şaire ait olabileceği ihtimalini arttırmaktadır.
Optimization of ESP performance through chemical treatment using a single capillary in the Apiay field
Authors: Duran Pabon Adriana Marcela , Murcia navas José Alberto
Published: October 2024

The future of production in the Apiay field lies in the T2 formation, although it poses significant challenges, such as high fluid encrustation and heavy crude oil production. These issues have led to strong emulsion problems and operational issues with many wells' electro-submersible pumping systems (ESPs).
In response, companies have decided that all wells with ESP equipment in the T2 formation should undergo downhole treatment using capillary scale inhibitors and fluidity improvers. However, due to operational and design constraints, some wells only have one capillary, making it difficult to prioritize and decide on a single treatment.
Ecopetrol and ChampionX have collaborated to develop a new flow improver that can be applied with the scale inhibitor in the same capillary without causing incompatibility or affecting product performance. This innovative solution was implemented in five wells, using 600 ppm for the flow improver, and 25 ppm for the scale inhibitor, resulting in a significant increase in crude oil production by up to 79%, USD 55.000 in cost savings in capillary system installation, 29% energy savings, and reduced emissions.
This successful application is innovative and unique in Colombia, and it sets an example for other fields facing similar challenges in the couuntry, offering a promising approach to leverage heavy crude oil production and transform the future of these fields.