bluuebunny/crossref_metadata_2025 huggingface dataset:
Eficácia e toxicidade dos regimes quimioterápicos no tratamento do Câncer Pancreático metastático
Authors: Silva Anderson Matheus Pereira da , Sousa Kaline Oliveira de , Fagundes Maria Eduarda Phaelante Brito , Santos Alice Veras , Regis Antônio Frederico Areias , Netto Luiz Alves de Oliveira , Cerqueira Nicolle Lima de , Pereira Kahlil Napy Charara Hamad , Justa José William Oliveira dos Santos , Mendes Luiza Leal , Oliveira Matheus Rodrigues da Silva de , Sales Guilherme Henrique Ramos Bezerra , Abreu Aline Moraes de
Published: August 2024

Em 2020, o câncer de pâncreas resultou em aproximadamente 495.773 novos casos e 466.003 mortes relacionadas à doença em todo o mundo. Além da opção cirúrgica, o tratamento do câncer pancreático abrange o uso de quimioterápicos, como o regime FOLFIRINOX, que combina fluorouracil, leucovorina, irinotecano e oxaliplatina. Outras abordagens incluem o uso de paclitaxel ligado à albumina em conjunto com gemcitabina e o irinotecano nanoliposomal associado a leucovorina e fluorouracil. O objetivo é fornecer uma visão atualizada que possa guiar decisões terapêuticas mais informadas, com ênfase na individualização do tratamento, visando maximizar os benefícios clínicos para uma população de pacientes diversificada. Esta revisão de literatura foi conduzida com o objetivo de avaliar a eficácia e a toxicidade dos regimes quimioterápicos utilizados no tratamento do câncer pancreático metastático. A revisão seguiu uma abordagem utilizando descritores booleanos para arantir a abrangência e a precisão na seleção dos estudos. Os estudos destacados na Tabelas revelaram que o regime FOLFIRINOX, apesar de sua elevada eficácia, está associado a uma toxicidade considerável, o que limita sua aplicabilidade em pacientes com estado geral debilitado. Entretanto, a integração do protocolo FOLFIRINOX são essenciais para melhorar o tempo de vida e qualidade desta neoplasia e melhorar os desfechos clínicos dos pacientes. A personalização do tratamento, considerando as características individuais dos pacientes e a inclusão de cuidados multidisciplinares, mostrou-se essencial para otimizar os resultados e melhorar a qualidade de vida.
Inteligência artificial: desafios e propostas para educação – possibilidade de aprendizagem
Authors: Giehl Clei Cenira , Camargo Simone Bortoluzzi , Lima Quézia Souza de , Pacheco Luci Mary Duso
Published: August 2024

Este artigo retrata alguns desafios que a educação poderá enfrentar com a chegada da Inteligência artificial (IA), em contrapartida, apresenta propostas para garantir o processo de aprendizagem por meio do uso da Inteligência Artificial na educação. Diante da boa nova que demonstra um potencial significativo para melhorar a eficiência e a personalização do ensino, também levanta questões importantes que precisam ser abordadas para garantir que a educação continue cumprindo seu papel vital na formação dos indivíduos e no desenvolvimento da sociedade. Uma das grandes dificuldades que a educação enfrentará com IA é assegurar a equidade. O principal objetivo deste estudo é propor ambientes de aprendizagem inovadores, personalizados e que incentivem a participação ativa dos alunos, enriquecendo a experiência educacional e promovendo um aprendizado mais significativo e integral. Para alcançar os objetivos propostos, foi realizada uma revisão bibliográfica sobre o uso da IA na educação, buscando identificar práticas e pesquisas recentes na área, relacionando, também com a abordagem que a formação continuada de professores deverá seguir, pensando na lógica da IA na educação. As propostas alcançadas neste artigo demonstram que a IA pode ser uma aliada valiosa no aprimoramento do processo de ensino e aprendizagem, proporcionando uma educação mais personalizada, engajadora e abrangente.
Launching the Career of William J. Tonesk of Schenectady, New York
Authors: Mazurkiewicz Anna
Published: August 2024

William J. Tonesk was born to a family of Polish immigrants who came from Russian and Austrian partitions of Poland. Born Władysław Jan Toniecki in Schenectady, New York, he can be traced in historical records using several last names: Tonski, Toniski, Tonick. While using his passion for Polish literature and theater as an advantage throughout his high school and college years, he invariably presented himself as an American. He settled for William J. Tonesk in 1932 as he entered Columbia University in New York. This article explores the opportunities available to the young man from Schenectady who skillfully navigated the ethnic advantage and native opportunity to spur his professional career. It also examines the support from Polish American organizations that was instrumental in keeping him intellectually and professionally engaged in the 1930s. Repeatedly, he multiplied the effects of the opportunities available to him, thus establishing a sound prequel to his professional career in the US intelligence establishment and diplomacy.
Peran Serta Masyarakat Dalam Meningkatkan Mutu Pendidikan Melalui Manajemen Berbasis Sekolah
Authors: Hasnawati Hasnawati
Published: August 2024

Penelitian ini bertujuan untuk mengetahui peran serta masyarakat dalam meningkatkan mutu pendidikan melalui manajemen berbasisis sekolah di SMK Analis Mandala Bhakti yang dilaksanakan pada semester genap. Jenis penelitian ini merupakan jenis penelitian deskriptif kualitatif yaitu menggambarkan secara umum tentang peran serta masyarakat dalam meningkatkan mutu pendidikan melalui manajemen berbasis sekolah. Objek dalam penelitian ini adalah guru dan komite sekolah SMK Analis Mandala Bhakti yang berjumlah 30 orang. Data yang diperoleh dianalisis dengan mengguakan tehnik analisis data mulai dari editing, tabulating kemudin analiting dan interpretasi dan terakhir adalah concluding atau memberikan kesimpulan data. Hasil penelitian menunjukkan bahwa peran serta masyarakat dapat meningkatkan mutu pendidikan melalui manajemen berbasis sekolah di SMK Analis Mandala Bhakti. Hal tersebut didasarkan pada hasil penelitian yang menunjukkan bahwa masyarakat telah berperan baik dan sangat baik sebanyak 85,2% dan sisanya sebanyak 14,8% belum berperan dengan baik
Perbandingan Efektifitas Resistance Training dengan Pemberian Konseling Informasi dan Edukasi tentang Penanggulangan Hot Flushes terhadap Intensitas Hot Flushes pada Ibu Perimenopause
Authors: Khoirunnisa Marjani , Ramadhan Fenni Valianda A. , Putri Magdalena Tri
Published: August 2024

Masa perimenopause dimulai 2-5 tahun sebelum menopause, terjadi perubahan fungsi reproduksi, hormon, fisik, maupun psikis. Dampak fisik paling banyak dialami, adalah perasaan panas (hot flush). Beberapa cara untuk mengatasi Hot Flushes, diantaranya mengkonsumsi makanan sehat, relaksasi, tidur cukup, olahraga dan terapi hormon. Olahraga merupakan upaya mengatasi Hot Flushes yang paling direkomendasikan, karena efektif namun minimal risiko khususnya jenis resistance. Efeknya bersifat sistemik untuk mengalirkan panas keluar tubuh. Penelitian ini bertujuan untuk mengetahui perbandingan efektifitas latihan fisik resistance dan pemberian KIE Hot Flushes terhadap intensitas Hot Flushes Karya penulisan ini disusun menggunakan study case literature review. Data diperoleh dengan cara mengukur intensitas Hot Flushes pada dua responden yang diberikan terapi berbeda, kemudian dievaluasi sebanyak 3 kali, yaitu pada hari 1; 4, dan 8. Hasil pmenelitian menunjukkan erdapat penurunan intensitas Hot Flushes pada ibu perimenopause yang diberikan terapi Resistance Training dibandingkan dengan ibu perimenopause yang diberikan terapi Konseling Informasi dan Edukasi Upaya Penanggulangan Hot Flushes (R1= sedang; sedang; ringan, vs R2= sedang; sedang; sedang).
Efektivitas Pemberian Aromaterapi Lavender terhadap Kualitas Tidur pada Ibu Menopause di RT04/RW15 Kec. Baleendah Kab. Bandung Tahun 2023
Authors: Nurwiliani Lia , Nency Aprilya , Dewi Meinasari Kurnia
Published: August 2024

Gangguan tidur merupakan salah satu gejala yang paling banyak dilaporkan oleh wanita menopause, Dampak gangguan tidur diantaranya adalah penurunan kualitas hidup, penurunan produktivitas kerja, peningkatan prevalensi kecemasan, depresi serta penyakit kardiovaskuler.(Proserpio et al., 2020) Perlu adanya upaya yang dilakukan bidan untuk mengatasi gangguan tidur pada menopause, pemberian essential oil Aromaterapi lavender merupakan salah satu cara untuk mengatasi gangguan tidur pada menopause. Tujuan penelitian ini adalah  mengetahui Efektifitas Aromtherapi Lavender terhadap kualitas tidur menopause di RT04 RW 15 Kec. Baleendah tahun 2023. Karya penulisan ini disusun menggunakan metode Study Case Literature Review. Data diperoleh dengan cara mengukur kualitas tidur menggunakan kuisioner PSQI terhadap 2 orang ibu menopause dengan intervensi aromaterapi lavender pada salah satunya, kemudian di evaluasi sebanyak 3 kali yaitu hari ke 1, 4 dan 7. Didapatkan hasil penelitian yaitu, terdapat pengurangan skor PSQI yang artinya perbaikan kuallitas tidur pada kedua responden. Akan tetapi pada responden dengan intervensi aromaterapi lavender memiliki perbaikan kualitas tidur yang lebih banyak dengan hasil kualitas tidur pada hari ke 1, 4, dan 7 yaitu, buruk, cukup kemudian baik. Berbeda dengan responden 2 diketahui kualitas tidur, yaitu buruk, buruk dan cukup. Disarankan pada ibu menopause dengan gangguan tidur untuk menggunakan aromaterapi lavender
Analisis Efektivitas Penerapan Pengembalian Pendahuluan Pajak Pertambahan Nilai sebagai Alternatif Percepatan Restitusi Pajak pada Klien SAR Tax & Management Consultant
Authors: Hakkam Sadewa , Winarningsih Srihadi
Published: August 2024

Dalam proses pemenuhan kewajiban perpajakan, Wajib Pajak sering kali mengalami permasalahan Lebih Bayar, salah satunya pada Pajak Pertambahan Nilai (PPN). Namun, ketika mengajukan Restitusi untuk mendapatkan pengembalian Lebih Bayar tersebut, Wajib Pajak merasa kurang puas karena proses yang rumit dan cukup lama. Oleh Karena itu, Direktorat Jenderal Pajak memberikan fasilitas Pengembalian Pendahuluan sebagai alternatif yang dapat digunakan oleh Wajib Pajak. Penelitian ini bertujuan untuk mengetahui efektivitas penerapan Pengembalian Pendahuluan PPN dibandingkan dengan Restitusi biasa, menganalisa dampak, manfaat dan kendalanya, serta untuk mengetahui Manajemen Restitusi yang baik untuk diterapkan perusahaan. Pengembalian Pendahuluan merupakan fasilitas yang disediakan DJP bagi Wajib Pajak atau Pengusaha Kena Pajak yang memerlukan pengembalian atas Lebih Bayar PPN. Penelitian terapan ini menggunakan pendekatan studi kasus dengan menggunakan metode penelitian kualitatif deskriptif dimana data yang digunakan adalah data primer dan sekunder yang diperoleh dari hasil observasi partisipan, wawancara, dan dokumentasi objek penelitian pada perusahaan tahun 2022. Hasil penelitian menunjukkan bahwa perusahaan telah menjalankan manajemen restitusi yang cukup baik dengan rutin melakukan Pembetulan SPT Masa PPN untuk memaksimalkan potensi Lebih Bayar PPN. Selanjutnya, dari hasil penerapan Pengembalian Pendahuluan terbukti efektif untuk meningkatkan Arus Kas Perusahaan menjadi lebih baik, dimana perusahaan mendapatkan pengembalian sebesar Rp204.338.490.368 yang dapat digunakan untuk kebutuhan perusahaan.
Analisis Komponen Utama untuk Menentukan Faktor Prioritas Perbaikan Jalan di Kota Dumai
Authors: Pratiwi Merina , Oemara Syarief Amiroel
Published: August 2024

Jalan sebagai infrastruktur transportasi sebagai sarana distribusi barang dan jasa. Semakin besar intensitas penggunaan jalan, maka berdampak pada kualitas jalan yang mengakibatkan jalan cepat rusak sehingga perlu dilakukan perbaikan jalan. Perbaikan jalan yang dilakukan tidak selalu cepat, hal ini karena adanya keterbatasan dana dari pemerintah pusat. Selain itu, penentuan prioritas perbaikan jalan masih dilakukan dengan memuat variabel yang diperoleh dari hasil survei membuat Dinas Pekerjaan Umum Kota Dumai kesulitan dalam menentukan variabel yang menjadi faktor prioritas perbaikan jalan di Kota Dumai. Untuk itu diperlukan analisis faktor perbaikan jalan kota Dumai yang menjadi prioritas untuk diperbaiki. Tujuan penelitian ini adalah menentukan faktor prioritas perbaikan jalan di Kota Dumai. Metode penelitian ini adalah metode penelitian kualitatif menggunakan Analisis Komponen Utama. Data untuk perbaikan jalan ini menggunakan data sekunder berdasarkan survei yang dikerjakan oleh Dinas Pekerjaan Umum. Data yang digunakan terdiri dari 50 data kelurahan kota Dumai dengan 6 variabel. Hasil penelitian menyatakan bahwa faktor yang menjadi prioritas penentu perbaikan jalan di Kota Dumai terdiri dari dua faktor. Faktor pertama yaitu Lebar Retakan mempunyai nilai eigen 2.385 dan dapat menjelaskan keragaman secara keseluruhan sebesar 47.703%. Faktor kedua yaitu Bekas Roda mempunyai nilai eigen sebesar 1.117 serta dapat secara keseluruhan menjelaskan keragaman sebesar 22.336%. Kedua faktor ini telah mampu menentukan prioritas penentu perbaikan jalan di Kota Dumai sebesar 70.039%.
Pengaruh Akupresur Titik BL23, GV3, GV4, dan BL40 dalam Mengurangi Nyeri Punggung Bawah pada Ibu Hamil Trimester III di Puskesmas Karang Rejo Kota Tarakan
Authors: Robaniyah Ulfatu , Purnamasari Agus , Retnowati Yuni , Farahdiba Idha , Aryanti Ririn , Rusmiati Rusmiati
Published: August 2024

Sekitar 50-70% dari wanita hamil pada umumnya mengeluh nyeri punggung bawah yang bisa dirasakan disemua tingkat usia kehamilan tidak diatasi dapat menimbulkan komplikasi dan mempengaruhi pekerjaan ibu serta insomnia yang menyebabkan keletihan dan iritabilitas. Terapi farmakologis dapat menimbulkan komplikasi seperti depresi pernafasan pada janin maupun efek ketergantungan. Sehingga nonfarmakologis (akupresur) perlu dilakukan dengan penekanan titik pengaktif (triggerpoint) yang merangsang pengeluaran hormon endorphin serta meningkatkan suplai darah dan oksigen pada daerah yang sakit sehingga nyeri punggung bawah berkurang. Penelitian ini bertujuan menganalisis pengaruh akupresur titik BL23, GV3, GV4 dan BL40 dalam mengurangi nyeri punggung bawah pada ibu hamil trimester III. Jenis penelitian kuantitatif dengan metode quasy experimen dengan pendekatan nonequivalent control group design. Populasi dalam penelitian adalah ibu hamil trimester III dengan keluhan nyeri punggung yang berjumlah 167 orang. Sampel dalam penelitian ini berjumlah 34 orang yang dipilih menggunakan tehnik purposive sampling dan dibagi menjadi kelompok kontrol dan perlakuan.  Analisa Bivariat dalam penelitian ini menggunakan uji Mann-Whitney. Hasil didapatkan p value 0,000 < 0,05 sehingga didapatkan hasil penelitian dengan kesimpulan terdapat pengaruh akupresur titik BL23, GV3, GV4 dan BL40 dalam mengurangi nyeri punggung bawah pada ibu hamil Trimester III di Puskesmas Karang Rejo. Pelayanan Komplementer akupresur titik BL23, GV3, GV4 dan BL40 dapat direkomenasikan sebagai terapi nonfarmakologi untuk mengurangi rasa nyeri punggung bawah pada ibu hamil trimester III.
Implementasi Penjualan Barang Elektronik Berbasis E-commerce pada Toko Al Zahro 786 Elektronik
Authors: Jagad Jundan Maulahaq Sapu , Wahyuningsih Endang
Published: August 2024

Toko Al Zahro 786 Elektronik belum memanfaatkan teknologi E-commerce, sehingga mengalami kesulitan dalam memperluas pasar dan meningkatkan efisiensi operasional. Penelitian ini bertujuan untuk mengimplementasikan sistem penjualan berbasis E-commerce di toko tersebut. Metode penelitian yang digunakan adalah penelitian dan pengembangan dengan pendekatan ADDIE (Analysis, Design, Development, Implementation, and Evaluation). Tahapan penelitian meliputi analisis kebutuhan, desain sistem, pengembangan, implementasi, dan evaluasi sistem. Hasil penelitian menunjukkan bahwa sistem E-commerce yang dikembangkan dapat memenuhi kebutuhan Toko Al Zahro 786 Elektronik dengan berbagai fitur seperti login, register, katalog, dashboard, tambah produk, halaman transaksi, profil pelanggan, detail produk, detail transaksi, manajemen akun, halaman transaksi karyawan, dan pengaturan profil. Pengujian blackbox yang dilakukan menunjukkan bahwa sistem berfungsi dengan baik dan sesuai harapan. Implementasi E-commerce ini diharapkan dapat meningkatkan efisiensi operasional, memperluas jangkauan pasar, dan meningkatkan kepuasan pelanggan di Toko Al Zahro 786 Elektronik.
Kajian Geomorfologi Daerah Batang Manyuruk dan Sekitarnya, Kabupaten Sawahlunto, Sumatera Barat
Authors: Apriliana Vira , Rochmana Yogie Zulkurnia
Published: August 2024

Daerah Batang Manyuruk dan Sekitarnya Kecamtan Talawi, Kabupaten Sawahlunto, Sumatera Barat memiliki kenampakan bentang alam dan bentuk lahan yang bervariasi dikarenakan indikasi bentukan geomorfologi yang khas dan beragam. Penelitian ini bertujuan untuk mengkaji kondisi geomorfologi dan satuan geomorfik daerah penelitian. Satuan geomorfik dapat digunakan sebagai informasi studi lanjutan untuk data penunjangan mitigasi bencana dan pengembangan wilayah. Metode penelitian menggunakan data hasil dari observasi lapangan dengan pengamatan aspek geologi yaitu, pengamatan bentuk lahan serta data pendukung berpa foto bentang alam dan analisis studio berbasis Sistem Informasi Geografis (SIG). Satuan geomorfik didapatkan dari hasil identifikasi beberapa aspek meliputi morfologi (morfografi dan morfometri), geomrofik atau morfodinamik. Hasil satuan geomorfik daerah penelitian dibagi menjadi: Perbukitan Tinggi Curam Denudasional menempati sekitar ±20% dari daerah penelitian yang terletak pada kelas lereng tingkat agak curam hingga sangat curam  bernilai (14%-40%) dengan elevasi 500-832 meter, Perbukitan  Rendah Agak Curam Denudasional menempati sekitar ±45% daerah penelitian yang terletak pada kelas lereng datar hingga agak curam (0-20%) dengan eleasi 200-500 meter, Perbukitan Lipatan Sesar menempati sekitar ±30% daerah penelitian dengan elevasi 200-300 meter memiliki kemiringan agak curam hingga curam bernilai (21%-55%) dan Pointbar menempati sekitar ±5% pada daerah penelitian, dengan elevasi 200-300 meter memiliki kemiringan lereng landai hingga agak curam bernilai (3-7%).
Efektivitas Teachable Machine dan Raspberry Pi dalam Mendeteksi Nominal Uang Kertas pada Alat Pendeteksi Model Virtual Reality
Authors: Susanto Bagas Nur , Nasrulah Muhammad Asad Catur , Endriawan Yahya Ginanjar , Aliyu Asniar
Published: August 2024

Menurut World  Health  Organization (WHO) ada sekitar 2,2 juta penduduk dunia mengalami kebutaan. Orang dengan gangguan penglihatan seperti tunanetra dan katarak sering kesulitan mengenali nominal uang. Kurangnya kejujuran antara penjual dan pembeli juga dapat menyebabkan mereka sering tertipu karena tidak mengetahui nilai uang yang dipegang. Penelitian ini bertujuan untuk mendapatkan model dan pendeteksi nominal uang kertas menggunakan Teachable Machine dan Raspberry Pi yang cocok diterapkan pada alat pendeteksi model virtual reality untuk membantu penyandang tunanetra. Sampel uang kertas yang digunakan adalah uang kertas edisi 2022 yang diambil melalui webcam Logitech C525 pada jarak 10 cm. Sampel ini kemudian dilatih menggunakan Teachable Machine untuk mendapatkan model dan diekspor dalam format TensorFlow Lite dan diimplementasikan pada Raspberry Pi yang sudah dilengkapi dengan library TensorFlow Lite, OpenCV, Pygame dan GPIO. Pendeteksian dilakukan pada jarak 7 cm dan 10 cm menutupi bagian depan dan belakang uang kertas. Hasil penelitian menunjukkan bahwa Rp. 2.000 memiliki tingkat keberhasilan deteksi tertinggi yaitu 100% pada berbagai kondisi, sedangkan Rp. 20.000, Rp. 50.000, dan Rp. 5.000 menunjukkan tingkat keberhasilan deteksi yang lebih rendah. Hasil rata-rata keberhasilan deteksi bagian depan dan belakang nominal uang kertas sebesar 73%. Berdasarkan hasil penelitian ini, Teachable Machine dan Raspberry Pi cukup efektif untuk diterapkan pada alat deteksi model virtual reality untuk membantu penyandang tunanetra.
Analysis Of the Different Analytical Model for Different Dark Matter Candidate
Authors: Wang Chuyi
Published: August 2024

As a matter of fact, dark matter candidate searching always been a key puzzle and challenge for contemporary physics. In retrospect, various approaches have been proposed in order to realize the detections and plenty of analytical models are given for possible searching. Nevertheless, there is no strong evidence for existence of certain type dark matter. With this in mind, this study will demonstrate the history and various different proposed models for dark matter candidate. To be specific, the WIMPs and axion, two most widely investigated candidate, will be discussed in detail. According to the analysis, the basic concepts, analytical descriptions, detection facilities as well as the state-of-art results will be illustrated. In the meantime, the current limitations for detections as well as searching for further research will be evaluated. Overall, these results shed light on guiding further exploration of dark matter as well as pave a path for dark matter candidate searching to confirm the physical model based on the upgrade of the advanced facilities.
Analysis Of the Latest Advancements and Prospects in Lithium-Ion Battery Technology
Authors: Wang Zhicheng
Published: August 2024

This paper provides an in-depth examination of the operational principles behind lithium-ion batteries, underscoring both their advantages and limitations. It also brings to light the latest technological advancements in the domain, including the development of batteries with higher energy densities, the innovation of rapid charging techniques for lithium-ion batteries, and the exploration of solid-state lithium-ion batteries. Additionally, this study introduces several optimization strategies and offers a forward-looking analysis of the future of these energy storage systems. The discussion extends to the introduction of cutting-edge cathode materials, the application of solid-state electrolytes, the implementation of intelligent charging solutions, and the adoption of integrated manufacturing approaches. These proposed strategies aim not only to improve the performance and safety of lithium-ion batteries but also to minimize production costs and mitigate environmental impacts. In conclusion, the paper emphasizes the indispensable role that lithium-ion batteries play in the evolution of energy storage technologies, advocating for ongoing research and development efforts to fulfill the growing demand for efficient, reliable, and eco-friendly energy solutions.
Models For Simulating Galaxies Formation
Authors: Lian Xiaoya
Published: August 2024

Simulating galaxy formation in a cosmological context is one of the biggest challenges that astrophysics faces today due to the vast range of scales and numerous physical processes involved. Over the past few decades, with the improvement of the algorithm and the development of computer technology, the simulation of pure gravity from the initial tens of particles to the number of particles in parsecs, a large number of different numerical simulation techniques are used to study the formation and evolution of structures in the universe. During this process, the resolution and precision of numerical simulation are improved continuously, and the description of the physical process of baryonic matter in the model is becoming more and more perfect. This article introduces the research progress of the galaxy's formation. Firstly, the paper explains the principle of the. Then, it reviews the recent progress and main achievements of related models and numerical equations and analyzes the main problems and challenges faced at present. Lastly, it discusses the conclusion and prospects of galaxy formation.
Frontier Optimization Strategies for Efficient Fuel Cell Vehicles
Authors: Liu Zhengyuan
Published: August 2024

Fuel cell vehicles (FCVs) represent a pivotal advancement in the evolution of future automobile technologies. This paper introduces a comprehensive approach to enhancing the performance of automotive fuel cells, employing the Predictive Trip Distance Adaptive Equivalent Consumption Minimum Strategy (PTDA-ECMS) objective function for predictive analysis. By developing innovative alkaline electrolyte membranes, catalysts, and electrode materials, and implementing hybrid power system management strategies for fuel cell and battery integration, this study aims to extend fuel cell longevity, improve system efficiency, and reduce operational costs. Additionally, the use of Inductively Coupled Plasma Mass Spectrometry (ICP-MS) for electric catalyst evaluation signifies a methodical exploration into fuel cells with enhanced service life, reduced production expenses, and superior overall performance. Such advancements are anticipated to decrease the operational costs of electric vehicles, thereby increasing marketability and facilitating more sustainable human transportation solutions. This paper provides a detailed overview of effective system optimization methods, including strategies to prolong battery life, alongside a summary of findings and prospects. Through these endeavors, the research underscores the significant potential of FCVs in contributing to the sustainable evolution of the automotive industry.
Analysis Of Fully Automated Feeder Automation in Fault Discrimination and Grid Automation Development
Authors: Zeng Yun
Published: August 2024

Feeder Automation (FA) emerges as a quintessential instrument for fault diagnostics within electrical distribution networks, markedly diminishing the extent of outage zones and facilitating expedited power reinstatement in unaffected sectors. This role underscores its pivotal contribution to the augmentation of grid automation processes. The paper delineates the foundational theories underpinning fully automated FA, encompassing aspects such as the requisite hardware apparatus, operational paradigms, inherent advantages, research trajectories, applicative contexts, challenges encountered, and future perspectives. Through elucidating the operational mechanics and theoretical underpinnings of two distinct fully automated FA modalities, coupled with case-study analyses, this study asserts the instrumental efficacy and precision of fully automated FA in troubleshooting, positioning it as a principal vector in the evolution of distribution networks. Furthermore, this research proffers novel resolutions to the impediments confronting fully automated FA, offering substantive contributions and insights pivotal for the advancement of grid automation paradigms.
The Research Related to the Effect of the LVMH’s Acquisition of Tiffany & Co.
Authors: Zhu Fantianjin
Published: August 2024

This paper makes a comprehensive analysis of the motivation of LVMH's acquisition of Tiffany & Co. The acquisition, which took place in 2020, was a significant move for both companies and had a profound impact on the luxury industry. A key motivation for LVMH's decision to acquire Tiffany & Co. was to expand its presence in the high-end jewelry market. By acquiring one of the world's most iconic and prestigious jewelry brands, the LVMH Group aims to strengthen its position as a global leader in luxury goods. This strategic move has allowed LVMH to diversify its product portfolio and attract a new customer base that vaTiffany & Co.ess elegance and craftsmanship. Based on the analysis of LVMH's financial reports in recent years and the collection of various expert data, this paper draws the conclusion that LVMH's acquisition of Tiffany & Co. is more beneficial than harmful. Highlights how the company is strategically positioned in the premium jewelry market by expanding distribution channels, cost synergies, and aligning itself with long-term growth targets.
Review Of the Light Extraction Efficiency of Gan Leds
Authors: Han Yiqing
Published: August 2024

Various new methods have emerged to enhance the light extraction efficiency (LEE) of Gallium Nitride (GaN)-based Light Emitting Diodes (LEDs),. This review examines several key techniques, including surface texturization, patterning of the GaN and substrate interface, chip geometry design, integration with photonic crystals, and epitaxial micro/nano structures. Surface texturization improves LEE by reducing light reflection and increasing scattering, although it may introduce surface defects. Interface patterning optimizes light propagation but increases manufacturing costs. Chip geometry design allows for specific light extraction paths but may pose manufacturing challenges due to complex designs. Photonic crystal technology enhances LEE though controlling light refraction but requires precise fabrication techniques. Among these approaches, epitaxial micro/nanostructures stand out for providing optimal control of the light extraction path while minimizing material waste and structural damage, despite the more demanding epitaxial conditions. Therefore, epitaxial micro/nano structures are considered the optimal strategy for significantly improving LEE in GaN-based LEDs, paving the way for more efficient and sustainable lighting technologies.
Korelasi Antara Fasilitas dan Lingkungan Pembelajaran dengan Capaian Pembelajaran Mahasiswa Sekolah Tinggi Ilmu Tarbiyah (STIT) Buntet Pesantren Cirebon
Authors: Mujadid Muhamad
Published: August 2024

Penelitian ini bertujuan untuk menganalisis korelasi antara fasilitas dan lingkungan pembelajaran secara bersamaan dengan capaian pembelajaran mahasiswa Metode yang digunakan dalam penelitian ini adalah metode kuantitatif yang termasuk dalam jenis korelasional. Populasi dalam penelitian ini adalah mahasiswa semester tiga sampai tujuh Sekolah Tinggi Ilmu Tarbiyah (STIT) Buntet Pesantren Cirebon sebanyak 100 mahasiswa. Sampel yang diambil sebanyak 41 mahasiswa dengan menggunakan teknik random sampling. Adapun teknik pengumpulan data menggunakan angket. Teknik analisis data yang digunakan adalah korelasi Product Moment Pearson  dan uji korelasi ganda yang didahului dengan uji validitas, uji reliabilitas, uji normalitas dan uji linearitas. Hasil penelitian ini menunjukkan bahwa  ada korelasi yang positif dan signifikan antara fasilitas dan lingkungan pembelajaran secara simultan dengan capaian pembelajaran, dengan nilai koefisien korelasi 0,785 Hal ini menunjukkan derajat korelasi yang kuat. Temuan ini berarti bahwa semakin baik fasilitas dan lingkungan pembelajaran maka semakin baik pula capaian pembelajaran.
MODERASI BERAGAMA DALAM SURAT AL-BAQARAH AYAT 143 MENURUT QURAISH SHIHAB DALAM PERSPEKTIF PENDIDIKAN ISLAM
Authors: Bakri bin Bakir Nanang Tantowi , Nafi’a Ilman , Abdul Kodir Faqihuddin
Published: August 2024

Penelitian ini bertujuan untuk mengetahui moderasi beragama dalam surat al-baqoroh. Kehidupan beragama di Indonesia belakangan ini mendapat sorotan dari berbagai pihak, baik dari dalam maupun luar negeri. Semua akibat konflik sosial berlatar belakang agama yang terus bermunculan di tengah-tengah masyarakat. Mulai dari kasus penodaan agama, perusakan rumah ibadah, ujaran kebencian, pendiskreditan suatu komunitas terhadap komunitas lain, terorisme, hingga bom bunuh diri. Fenomena ini mau tidak mau memperburuk sentimen keagamaan di Indonesia. Sentimen keagamaan yang tajam membuat bangsa terpecah belah berdasarkan agama dan kepercayaan. Menjadikan rasa kekeluargaan, persatuan dan keharmonisan bangsa menjadi renggang. Kegagalan mendialogkan pemahaman agama dengan realitas sosial di Indonesia yang multikultural, plural, dan beragam menjadi akar konflik sosial yang berlatar belakang agama. Kegagalan dialog pemahaman dialami oleh kelompok garis keras yang tidak mau bertoleransi dan sulit berkompromi dengan paham agama lain yang berbeda. Untuk itu pendidikan Islam perlu dikaji apakah ada kaitannya erat dengan moderasi beragama dalam Al-Qur'an Surat Al Baqarah Ayat 143 menurut Quraish Shihab atau sebaliknya tidak ada kaitannya sama sekali atau malah berbeda, tentunya hal ini akan dilihat dari aspek kajiannya dari sudut pandang Quraish Shihab tentang moderasi beragama dan dari sudut pandang penafsiran Surat Al Baqarah Ayat 143 dalam perspektif Pendidikan Islam.
Self-Discovery Through the ‘Other’: Reshaping Consciousness Among Sufism, Literature and Philosophy in Rumi’s The Merchant and the Parrot and Montesquieu’s The Persian Letters
Authors: Hassanin Shaimaa Mohamed , AlAhmadi Nesreen Saud , Hasan Ahmed Hasan Anwar
Published: August 2024

This research paper explores how engaging with the 'other' can challenge and reshape one's preconceptions, focusing on Edmund Husserl's concept of intentional consciousness. It examines The Merchant and the Parrot by Jalal Al-Din Rumi (1207 –1273) and The Persian Letters by Charles de Secondat, Baron de Montesquieu (1689 –1755), highlighting how encounters with non-Western characters lead to self-reflection. By drawing on Husserl's theory that consciousness is always directed towards an object, it argues that interactions with individuals from different backgrounds allow for a reconsideration of one's culturally conditioned perspectives. Through the lens of intentionality, the paper investigates how observations of French culture by the Persians and the parrot's words prompt a reassessment of ingrained beliefs by accessing deeper truths beyond superficial consciousness. By applying Husserl's framework that consciousness is influenced by but not limited to its cultural context, it explores how the 'other' characters in the analyzed works offer unfiltered insights due to their outsider perspective. The research paper suggests that respectful dialogue with diverse viewpoints, as depicted in literary works, can catalyze expanding awareness, challenging biases, and fostering new philosophical insights in alignment with Husserl's concept of intentional consciousness. This interdisciplinary analysis connects the literary texts with Husserl's ideas to illustrate how cultural exchanges and encounters with the 'other' can prompt self-reflection and philosophical growth.
PREVENTING TERATOGENESIS BY ENHANCING THE RADIOLOGY TECHNIQUES WITH COMPUTER VISION
Authors: Ali Shah Syed Osama , Eman Alishba
Published: August 2024

This research paper presents a novel AI-driven approach utilizing Convolutional Neural Networks (CNNs) and advanced computer vision techniques for monitoring and controlling teratogenesis caused by radiography in pregnant patients. The developed AI system integrates real-time radiation monitoring, decision support, and image enhancement modules to provide comprehensive and personalized risk assessments during radiography procedures. The CNN model accurately analyzes radiography images, estimating radiation dose and assessing teratogenic risk in real-time. Image enhancement techniques enhance image quality without compromising diagnostic integrity. The AI system seamlessly integrates with electronic health records (EHRs) to access patient information, enabling personalized recommendations. Ethical considerations encompass data privacy, security, and mitigating biases. Rigorous evaluation demonstrates the AI system's efficacy in improving patient safety during radiography. The potential for AI-driven advancements in patient safety and healthcare outcomes underscores the transformative impact of AI technology in radiology and beyond.
Investigation of the relationship between orthorexic tendencies and some anthropometric measurements and variables in university students
Authors: Erkilic Tugce , Bayraktar Bulent , Erkilic Ali , Ozcan Gulbahar , Bozok Ummu , Bulbul Ali , Turan Merve
Published: August 2024

Orthorexia nervosa (ON) is a type of eating disorder marked by an excessive preoccupation with eating healthily to preserve and promote health, which surpasses normal levels of concern. This study aims to investigate the correlation between orthorexic tendencies, anthropometric measurements, and several other characteristics among university students. A cross-sectional study was done with a sample size of 307 university students from various departments, consisting of 228 females and 79 males. The data-gathering process consisted of administering a demographic information form and the ORTO-11 questionnaire. Anthropometric measurements, such as weight, height, waist circumference, hip circumference, and chest circumference, were measured. In addition, Body Mass Index (BMI) was calculated. The TANITA BC-418 equipment was used to measure the weight of the participants, while a flexible tape measure was used to measure their height, waist circumference, hip circumference, and chest circumference. The BMI was calculated by the individual's weight (in kilograms) by the square of their height (in meters). The data analysis encompassed the utilization of descriptive statistics, t-tests, variance analysis, and Pearson correlation analysis. A score of 25 or lower on the ORTO-11 scale was categorized as orthorexic, whereas a score higher than 25 was deemed normal. The average age and orthorexia scores of the subjects were 20.81±1.86 and 27.76±4.42 for females, and 21.38±4.14 and 28.11±4.37 for males, respectively. It was determined that 29.3% of the participants were found to display orthorexic tendencies, while the remaining 70.7% did not. There were no statistically significant variations in age, hip circumference, and orthorexia scores across genders (p>0.05). No statistically significant relationship was found between the total orthorexia scores and BMIs of the individuals (r=-.051, p>0.05). ON is associated with psychological and social complications, which in turn contribute to the development of disordered eating patterns. The results of this study indicate that determining the frequency of orthorexic tendencies among university students may contribute to the development of strategies for its prevention.
Which type of allergic rhinitis is more associated with impaired quality of life and sleep and increased symptoms of anxiety and depression?
Authors: Ozturk Betul , Kayhan Mehmet
Published: August 2024

The present study aimed to assess the symptoms of anxiety and depression, quality of life (QoL), and sleep quality in patients with allergic rhinitis (AR). Additionally, the study sought to analyze the relationship between these parameters and the severity of the disease, duration of symptoms, seasonality, predominant symptoms, and the coexistence of asthma. A total of 88 patients with AR without any systemic comorbidity and 78 healthy controls were enrolled. Patients with AR were grouped as mild or moderate-severe, seasonal or perennial, intermittent or persistent, and sneezers-runners or blockers. The Hospital Anxiety Depression Scale (HADS), Short Form-36 (SF-36), and Single-item Sleep Quality Scale (SQS) were assessed. HADS depression and anxiety scores were elevated in patients with AR compared to healthy controls (p=0.006 and p=0.025, respectively), and SF-36 physical role functionality and general health perception domains and SQS scores were lower (p<0.001, p<0.001, and p=0.004, sequentially). HADS anxiety scores were more elevated in individuals with AR and concomitant asthma (p=0.037). Higher depression and anxiety scores and lower sleep quality were observed in the moderate-severe group relative to the mild group (p=0.038, p=0.028, and p<0.001, respectively), and in the persistent group relative to the intermittent group (p=0.010, p=0.030, and p<0.001 sequentially). Blockers had higher HADS scores (p=0.010 and p=0.015, respectively) and lower sleep quality and social role functioning than sneezers-runners (p=0.040 and p=0.034, in sequence). Our study showed that AR downgraded patients' well-being. The severity, persistence, perennialism, nasal obstruction, and asthma comorbidity of the disease in question had a deleterious effect on the QoL and sleep, as well as mood.
Serum relaxin-3 and galanin levels in individuals with erectile dysfunction with and without type 2 diabetes mellitus
Authors: Yilmaz Umit , Burlukkara Salih , Demir Demirhan
Published: August 2024

This study was designed to determine the serum relaxin-3 and galanin levels in individuals with erectile dysfunction with and without type 2 diabetes mellitus (T2DM). A total of 154 individuals aged 30-60 were included in the study and the participants were divided into three groups: D-ED group (individuals with T2DM and ED) (n=49), ND-ED group (individuals with ED without T2DM) (n=55), and control group (individuals without T2DM and ED) (n=50). The age, BMI, and IIEF-5 score were recorded for all participants. The HDL, LDL, triglycerides, cholesterol, HbA1c and testosterone were determined from the blood taken from the participants, and galanin and relaxin-3 levels were measured in serum samples by ELISA method. The IIEF-5 score of the D-ED group was statistically lower than that of the ND-ED and control groups, and the IIEF-5 score of the ND-ED group was also lower than that of the control group. Serum testosterone levels in the control group were statistically higher than in the D-ED and ND-ED groups. The galanin level of the D-ED group was elevated than the control and ND-ED groups, but the galanin level of the ND-ED group was lower than the control group. The relaxin-3 levels were decreased in the D-ED and ND-ED groups compared to the control group. Galanin levels increased in individuals with T2DM and ED, however decreased in individuals with ED without T2DM. In addition, reduced relaxin-3 level may play a role in the development of ED.
LORAZEPAM FOR THE MANAGEMENT OF POSTERIOR FOSSA MUTISM: A CASE REPORT
Authors: Alfakeh Sulhi , Alesa Alaa , Sabbagh Abdulrahman J. , Basurrah Abdulaziz A.
Published: August 2024

Posterior Fossa Syndrome (PFS) is a condition that can develop in children and adults following a cerebellar tumor resection surgery. The syndrome is characterized by multiple symptoms, including mutism, personality changes, and mobility problems. We present a case of a four-year-old boy diagnosed with posterior fossa tumor with secondary hydrocephalus who underwent an uneventful total resection of the tumor and developed posterior fossa syndrome, including mutism, was managed using lorazepam and made a full recovery of almost all of the symptoms he developed. Posterior fossa syndrome has multiple symptoms, most of which are usually transient. The exact pathophysiology and time to recovery are still not fully known. Patients with posterior fossa syndrome are managed with a multi- disciplinary approach. Mutism resulting from this syndrome is proven to be successfully managed by lorazepam.
LACUNAR STROKE AND AUTONOMIC DYSFUNCTION
Authors: Eliacik Sinan
Published: August 2024

Objective: This study aimed to investigate the association between autonomic function and the lacunar strokes, along with a review of the literature to elucidate the interplay between the autonomic nervous system and stroke outcomes. Methods: Thirty-two lacunar stroke patients and 28 healthy age matched control subjects were included. Sympathetic Skin Response (SSR) and R-R Interval Variation (RRIV) values were measured. In the both groups, SSR and R-RIV during rest and deep breathing were recorded for the assessment of sympathetic and parasympathetic function, respectively. Results: The present study revealed significant differences in the autonomic function of patients with lacunar stroke compared with those in the control group. For the SSR, the patients showed a much lower amplitude and longer latency, indicating impaired sympathetic activity. Moreover, the R-R interval variability, both at rest and during deep breathing, was altered, suggesting changes in heart rate variability and parasympathetic function. Conclusion: These study results highlight a marked autonomic dysfunction in patients with lacunar stroke, which has significant implications for clinical management and prognosis.
The synthesis and toxicological evaluation of carbon dots, and their application in oral health
Authors:   , Fu Cuicui
Published: August 2024

Carbon dots (CDs) are amorphous or nanocrystalline sp2 or sp3 carbon clusters with dimensions smaller than 10 nm. In this thesis, we synthesized CDs from various sources, characterized their properties, and evaluated their toxicity in vitro and in vivo. Moreover, we expanded the applications of CDs to a Sjögren’s syndrome (SS) mouse model (NOD) and explored their distribution in vivo and the potential immunomodulatory mechanism. Furthermore, we investigated the effects of CDs on anti-demineralization on the surfaces of hydroxyapatite to prevent calcium loss.
Hipotireoidismo: uma revisão literária sobre fisiopatologia, diagnóstico e tratamento avançado
Authors: Branco Gabrielle Gontijo Guimarães , Bueno Giulia Zoccoli , Ohana Giovanna Gontijo Alves de Sousa , Galdino Letícia Souza Silva , Morais Nathália Paim , Rodrigues Flávia Alves Jeangregório , Silva Gabriel Felipe Sant Ana , Amaral Juliana Oliveira , Pedrosa Maria Luiza Ribeiro , Carvalho Luciana Azevedo Silva Mantovani de , Costa Julia Selestino , Rodrigues Túlio Alves Jeangregório , Aguiar Maria Fernanda Pereira , Trillo Maria Luisa Nicolichi , Torquato Lorena Brito
Published: August 2024

O hipotireoidismo é uma condição prevalente, caracterizada pela produção insuficiente dos hormônios T4 e T3 pela glândula tireoide, afetando múltiplos sistemas orgânicos e podendo levar a complicações graves como infertilidade e doenças cardiovasculares. Historicamente tratado com extrato tireoidiano, o advento da levotiroxina sintética na década de 1970 revolucionou o manejo da doença, melhorando a compreensão sobre sua fisiopatologia e tratamento. A qualidade de vida dos pacientes com hipotireoidismo é significativamente impactada, com sintomas que vão desde letargia e ganho de peso até problemas emocionais como depressão. O diagnóstico é baseado em avaliações clínicas e laboratoriais, incluindo a dosagem de TSH e hormônios tireoidianos, sendo crucial para evitar complicações graves associadas à doença. A etiologia do hipotireoidismo pode ser autoimune, como a Tireoidite de Hashimoto, ou resultante de danos à tireoide por diversas causas, e é influenciada por fatores genéticos e ambientais. A fisiopatologia envolve o eixo hipotálamo-hipófise-tireoide e a conversão de T4 em T3, afetando o metabolismo e a função cardiovascular. O tratamento padrão é a reposição hormonal com levotiroxina, com ajustes baseados em monitoramento dos níveis de TSH, visando normalizar esses níveis e reduzir sintomas. A abordagem terapêutica pode variar, especialmente em pacientes com hipotireoidismo subclínico, e deve ser individualizada, considerando comorbidades e características específicas de cada paciente. A identificação de biomarcadores mais precisos e a compreensão mais aprofundada dos fatores genéticos e ambientais associados ao hipotireoidismo poderão levar a estratégias de tratamento mais eficazes e personalizadas.