bluuebunny/crossref_metadata_2025 huggingface dataset:
Significant elevated CXCL14 and decreased IL-39 levels in patients with tuberculosis
Authors: Ding Min , Wang Hong-xu , Gao Si-jia , Lai Xiao-fei , Li An-long , Bao Jia-jia , Hosyanto Felycia-Fernanda , Xu Lei
Published: May 2023

To explore the serum levels of IL-39, CXCL14, and IL-19 in patients with tuberculosis (TB) along with their clinical significances and their concentration changes in macrophages after Bacille Calmette-Guérin vaccine (BCG) or Mycobacterium tuberculosis (M. tb) H37Rv stimulation in vitro. The serum levels of IL-39, CXCL14, and IL-19 of 38 TB patients, and 20 healthy staff members were measured by enzyme-linked immunosorbent assay. Moreover, the levels of IL-19, CXCL14, and IL-39 in cultured THP-1 macrophages were detected at 12, 24, and 48 h after stimulation with BCG or M. tb H37Rv strains. It was found the serum level of IL-39 was significantly reduced and CXCL14 was remarkably elevated in TB patients. In vitro, at 48 h after stimulation, IL-39 level of cultured THP-1 macrophages in the H37Rv group was significantly lower than that in the BCG and control groups, and the CXCL14 level of cultured THP-1 macrophages in the H37Rv stimulation group was remarkably higher than that in the control group. Therefore, IL-39 and CXCL14 may be involved the pathogenesis of TB, and serum IL-39 and CXCL14 could potentially serve as a new biomarker of TB.
Gemella morbillorum infective endocarditis: A case report and literature review
Authors: Cao Xuejie , Yuan Lichao
Published: May 2023

Infective endocarditis (IE) caused by Gemella morbillorum is rare. Consequently, little is known about the natural course of endocarditis caused by this pathogen. This report describes the case of a 37-year-old male patient with G. morbillorum endocarditis. The patient was hospitalized for a fever of unknown origin. He complained of intermittent fever of unknown origin for 2 months. He had also undergone root canal therapy for pulpitis a month ago. After admission, the infectious pathogen G. morbillorum was identified using metagenomic next-generation sequence technology. The anaerobic blood culture bottle showed only Gram-positive cocci. Transthoracic echocardiography showed 10 mm vegetation on the aorta, which met the IE diagnostic Duke’s criteria, and the patient was diagnosed with G. morbillorum IE. Because no bacterial colonies were formed on the culture, the drug sensitivity test could not be conducted. Ceftriaxone anti-infective drugs are based on careful consideration of the literature and patient. Six days after antibiotic treatment in our department, the patient was discharged from the hospital in stable condition and had no adverse reactions at 1 week of follow-up. To help clinicians better understand the disease of G. morbillorum IE, we also reviewed and discussed the relevant cases published after 2010 when presenting the report.
Twinned single crystal structure of Li4P2S6
Authors: Ben Yahia Hamdi , Motohashi Kota , Mori Shigeo , Sakuda Atsushi , Hayashi Akitoshi
Published: May 2023

Yellow needles-like single crystals of Li4P2S6 were obtained serendipitously during the preparation of Li7P3S10O. The twinned crystal structure of Li4P2S6 was determined from single-crystal X-ray diffraction data [wR(F
2) = 0.069, 716 reflections, 40 variables]. Li4P2S6 crystallizes in the trigonal system, space group

P

3
‾

m
1

$P\overline{3}m1$

(N° 164), a = 10.5042(8) Å, c = 6.5837(6) Å, V = 629.11(9) Å3 and Z = 2. The lithium octahedra form a [Li4S6]8− honeycomb-like structure within which diphosphate units are located. The comparison of our crystal structure to those of P63/mcm-,

P

3
‾

1
m

$P\overline{3}1m$

-, and P321-Li4P2S6 demonstrated group-subgroup relationships and associated the disorder or order of the phosphorus atoms within the identical [Li4S6]8− 3d-frameworks to the choice of the unit cell (the subcell with a ∼ 6.07 Å vs. the supercell with a ∼ 10.5 Å).
RESISTANCE OF ADDITIONAL ROOFING UNDERLAYS OF PITCHED ROOFS AGAINST ARTIFICIAL AND NATURAL AGEING
Authors: NAVARA TOMÁŠ
Published: May 2023

In this paper, the author deals with the resistance of light polymer foils based on microporous functional film, used as additional waterproofing layers of pitched roofs. He exposes these foils to the effects of natural ageing and the effects of artificial ageing according to the methodology of the European test standard. Subsequently, it verifies the tensile properties of the exposed foils and compares the effects of natural and artificial ageing in order to determine the possible cause of premature degradation of these materials, which often occurs in practice. He concludes that the cause of this degradation is not excessive leniency of testing standards, but the insufficient quality of materials supplied to the European market.
MULTI-CRITERIA NUMERICAL OPTIMIZATION OF MECHANICAL PROPERTIES IN ULTRASONIC WELDING PROCESS PARAMETERS OF PVC-COATED HYBRID TEXTILES FOR WEATHER PROTECTION
Authors: HUSSEN MUKTAR SEID , KYOSEV YORDAN , PIETSCH KATHRIN , BOLL JESSICA , KABISH ABERA KECHI
Published: May 2023

A series of research was carried out to determine the correlation between ultrasonic welding process parameters and weld seam mechanical properties. However, multi-objective numerical optimization of coated hybrid textiles for weather protection has not been addressed. To ensure a comprehensive evaluation of ultrasonic weld seams, the research investigates the optimal solution of the multi-objective function of ultrasonic welding process parameters and formulates a single criteria objective function. Lapped and superimposed types of seams were applied based on 33 factorial designs of experiments for 6 and 12 mm welding widths. Single-criteria objective functions instead of three independent problems were developed as a generalized utility function. A single-criteria optimization method was introduced through predetermined weight and normalization within the range of acceptable/unacceptable values. Numerical and graphical optimization methods were also applied to determine possible optimal solutions through generalized utility functions. The best optimal value of the generalized utility function (0.670425 and 0.944374) was attained at welding speed (2 and 2.01564 m/min), power (93.756 and 117.973 W), and pressure force (198.803 and 239.756 N) of 6 and 12 mm welding widths, respectively. The acceptable range of satisfactory values was determined for the roof and wall of awnings and camping tents through standard, in which seam performance level indicated. Nonlinear quadratic numerical models were formulated to estimate the generalized utility function, and their results were close to the regressed diagonal line against the actual points. The statistical analysis was shown a statistically significant effect of welding process parameters on the generalized utility function.
ANTIMICROBIAL ACTIVITY OF COTTON FIBRES TREATED WITH PARTICLES EXTRACTED FROM CITRUS PLANTS: A REVIEW
Authors: ALI REHMAT , KARAMAT, UM E HABIBA , NAZIR HAFIZA SABA , BAIG MIRZA MUHAMMED MOHSIN , KHAN BILAL ALAM , ULLAH ASAD , USMAN OSAMA , WASEEM TANYA , TAHIR MUHAMMAD FARRUKH
Published: May 2023

Nanotechnology is an emerging technology in textile sector for the fabrication of functional textiles with different properties such as antibacterial, hydrophobicity, UV-protection, flame retardancy, anti-static and self-cleaning. In current COVID-19 crises, the development of antimicrobial textiles through the deposition of nanoparticles has emerged as a research subject of particular interest. Recently, the green-synthesis of nanoparticles from plant extracts has become an effective alternative to conventional physical and chemical synthesis methods due to being environmentally benign and nontoxic. In this review article, the significance of nanotechnology in antibacterial finishing of textiles, mechanism of antibacterial activity of nanoparticles, significance of green synthesis methods for nanoparticles have been discussed. The green-synthesis of different nanoparticles from the citrus plant extracts and their application on textiles for imparting antibacterial activity is reviewed in particular. The chemical composition of citrus plant extracts and their role as bioreductants in the synthesis of nanoparticles is also highlighted. Moreover, different qualitative and quantitative standard testing protocols employed for the antimicrobial characterization of plant extracts and textiles have been discussed. The major challenges and limitations associated with the plant-based biosynthesis of nanoparticles have also been highlighted.
Seeing Fotis: Slavery and Gender in Apuleius’ Metamorphoses
Authors: Stewart Roberta
Published: May 2023

The portrayal of the enslaved woman Fotis in Apuleius’ Metamorphoses exposes the intersection of gender, sexuality, and slavery. Apuleius’ novel allows a window into interactions beyond the relationship of slaveholder and the enslaved person over whom s/he claimed dominium. Centering Fotis in Apuleius’ narrative shows how a discourse of slavery worked: an enslaved woman is made present as a body that may be sexualized and surrounded with fantasies of sex and violence. The sexual episodes of Lucius and Fotis reveal an aesthetic, facilitated by the system of slavery, of consuming bodies, watching bodies consumed by violence, and framing effacement and degradation as romance, an operation of power at the core of chattel slavery.
Mythic Landscapes and Ecologies of Suffering in Sophocles’ Philoctetes
Authors: Haselswerdt Ella
Published: May 2023

On some accounts, Sophocles’ Philoctetes is most notable for what it lacks: alone among the extant Attic tragedies, there are no women in the dramatis personae; alone among the extant plays of Sophocles, no characters die; and the chorus plays a relatively diminished role, adhering most closely to Aristotle’s injunction in the Poetics that a chorus should take on the role of an actor. But when viewed through the lens of ecocritical feminism and vibrant materialism, notably the work of Donna Haraway, Mel Chen, Jane Bennett, and Anna Tsing, the play’s landscape, the island of Lemnos, comes to life; and it teems with feminine energies as well as compromised and complicated animacies, while the chorus serves as an empathic focalizer and world-builder. This paper argues that in addition to animating the island’s material ecosystem, Sophocles conjures Lemnos’ mythic ecosystem, most notably the tale of the notorious, murderous, and malodorous Lemnian Women. All of these elements cohere to characterize Philoctetes as an abject, sterile menstruator. Furthermore, the chorus’s brief, strange Hymn to Gaia encapsulates the play’s tension between a masculine, heroic, teleological narrative and the feminine, primordial, bestial world of Lemnos. These dynamics are further considered through the lens of fifth-century Athenian colonization, the story of the indigenous Lemnian Pelasgians, and a colonial reading of the Odyssey’s Cyclopeia. Finally, the paper explores the close, mutually constitutive relationship between text, landscape, and body via the popularity, in later antiquity, of pharmacological applications of Lemnian Earth, used to treat, among other ailments, snakebites and menstruation.
Siphon, or What Was the Plot? Revisiting Sylvia Wynter’s “Novel and History, Plot and Plantation”
Authors: Parsard Kaneesha Cherelle
Published: May 2023

This essay revisits Sylvia Wynter’s 1971 essay “Novel and History, Plot and Plantation” in relation to a quandary: the history of provision grounds not only as a resource but also as an initiation into property relations during and after West Indian slavery. In this light, the plot becomes a space of instruction in how to become a free subject through exchange. The essay draws out the plot’s histories of dispossession, enclosure, and dispute. Ultimately, it offers another term, siphon, as the condition of the overlapping conjunctures of West Indian emancipation and the postcolonial.
On Sitting
Authors: Gandhi Leela
Published: May 2023

By way of a formal experiment in speculative entanglement, this essay hopes to set in motion an account of nonviolence as a disposition vested in principles of relationship rather than renunciation. It also counters what the cultural anthropologist Thomas Trautmann has described as the “theory-deadness” of non-Western antiquities—a double effect, we might argue, of their disciplinary incarceration by possessive orientalist modes of expertise and policing by various insurgent cultural nationalisms.
Diagnosis of 17-alpha hydroxylase deficiency performed late in life in a patient with a 46,XY karyotype
Authors: Bouça Bruno , Cascão Mariana , Fiúza Pedro , Amaral Sara , Bogalho Paula , Silva-Nunes José
Published: May 2023

17-Alpha-hydroxylase deficiency (17OHD) is a rare autosomal recessive disease, representing 1% of cases of congenital adrenal hyperplasia. A 44-year-old female presented to the emergency department complaining of generalized asthenia and polyarthralgia for about 2 weeks. On examination, she was hypertensive (174/100 mmHg), and laboratory results revealed hypokalemia and hypocortisolism. She had an uncharacteristic morphotype, BMI of 16.7 kg/m2, cutaneous hyperpigmentation, and Tanner stage M1P1, with normal female external genitalia. She reported to have primary amenorrhea. Further analytical evaluations of her hormone levels were performed CT scan revealed adrenal bilateral hyperplasia and absence of female internal genitalia. A nodular lesion was observed in the left inguinal canal with 25 × 10 mm, compatible with a testicular remnant. Genetic analysis identified the c.3G>A p.(Met1?) variant in homozygosity in the CYP17A1 gene, classified as pathogenic, confirming the diagnosis of 17OHD. Karyotype analysis was compatible with 46,XY. The association of severe hypokalemia, hypertension, hypocortisolism, and oligo/amenorrhea and the absence of secondary sexual characteristics favored the diagnosis of 17OHD, confirmed by genetic testing. As in other published clinical cases, diagnosis outside pediatric age is not rare and should be considered when severe hypokalemia occurs in hypertensive adults with a lack of secondary sexual characteristics.

Learning points

The association of severe hypokalemia, hypertension, hypocortisolism, and oligo/amenorrhea and the absence of secondary sexual characteristics favor the diagnosis of 17-alpha-hydroxylase deficiency (17OHD).

Diagnosis outside pediatric age is not rare.

17OHD should be considered when severe hypokalemia occurs in hypertensive adults with a lack of secondary sexual characteristics.
Mycotoxins associated with maize wastes treated with comprised capsule of Spirulina platensis biomass
Authors: Al-Rajhi Aisha M. H. , Salem Olfat M. A. , Mohammad Abeer M. , Abdel Ghany Tarek M.
Published: May 2023

Spirulina platensis has roles in biotechnological product advancement due to its safety for humans and animals. Analysis of S. platensis extract by high-performance liquid chromatography reflected the presence of 14 phenolic and flavonoid compounds with different concentrations such as ellagic acid (333 µg/g), gallic acid (294 µg/g), methyl gallate (147 µg/g), naringenin (144 µg/g), and chlorogenic acid (142 µg/g). The isolated Aspergillus flavus from silage of maize was tested to evaluate the effect of S. platensis extract on aflatoxins B1, B2, G1, and G2 production. The treated silage with S. platensis extract showed the presence of 37±0.33 ppb, 0.59±0.16 ppb, 0.26±0.22 ppb, and 0.21±0.18 ppb compared to un-treated silage that showed 3.14±0.15 ppb, 0.81±0.08 ppb, 0.46±0.05 ppb, and 0.26±0.23 ppb aflatoxins of B1, B2, G1, and G2. These results were shown on the 10th day of incubation. On the 15th day of incubation, the treated silage showed less mycotoxins than un-treated silage. At different incubation periods, glucosamine was estimated as a growth development biomarker. The content of glucosamine was inhibited as a result of the effect of S. platensis extract on fungus growth with 53.71%, 49.19%, 47.84%, 38.47%, and 35.72% inhibition on the 3rd, 6th, 9th, 12th, and 15th day.
Process maximization of salt free reactive dyeing on cotton using Taguchi approach
Authors: Kabir Shekh Md. Mamun
Published: May 2023

This study optimized the salt free reactive dyeing process using the Taguchi approach. Dyeing of cotton fabric with reactive dyes is popular because of its bright and brilliant color in various shade ranges. Cationization with ALBAFIX-WFF and the dyeing process on cotton fabric was carried out using the exhaust method. To determine the optimum process conditions, two types of multiple characteristic parameters, including the single characteristic value conversion method and the process maximization method, were used on the basis of color strength (K/S) and wash fastness. The single characteristic value conversion method confirmed that the optimum process condition was a cationization temperature of 40 °C and a dyeing pH of 11. Most importantly, the optimal conditions were confirmed by the process maximization method as a concentration of ALBAFIX-WFF 30 g/L, cationization temperature at 80 °C, dyeing pH 12, and material-to-liquor ratio (M:L) of 1:5. More suitable dyeing properties are also achieved by the process maximization method.
A consolidation of degraded lime wooden support from heritage objects using two types of consolidant,
Authors: Avram Anamaria , Ionescu Constantin Stefan , Lunguleasa Aurel
Published: May 2023

The novelty of the research consists in the fact that the decayed wood was taken from an old icon, on which several consolidation treatments were applied, and the improvement indices of the decayed wood (by Anobiidae insects) were also determined. This research investigated two types of the most used consolidant (Paraloid B72 10% and Regalrez 1126 25%) solubilized in three types of solvents, to improve the properties of lime wood samples coming from cultural heritage objects that presented different degrees of degradation. Testing methodology for dimensional changes and wood swelling due to solvents impregnation, retention of consolidant in the degraded Tilia cordata wood, and the effectiveness of the consolidation treatment by the Mark hardness method was extensively presented. The highest amount of consolidant was observed when using Regalrez solution, and the lowest amount of consolidant was determined for Paraloid B72 solubilized in acetone. As a general conclusion, the use of Paraloid B72 or Regalrez 1126 for the consolidation of old and degraded lime wood, regardless of the type of solubilizer, will lead to stabilization of the wood degraded properties and the life span of the heritage object.
Kultūros organizacijų pasitelkiamų priemonių tipų ir formų, siekiamo atlygio ir išankstinio žinojimo įtaka auditorijos įsitraukimui
Authors:   , Jurėnė Skaistė
Published: May 2023

The impact of the types and forms of tools used by cultural organisations, prior knowledge, and seeking gratification on audience engagement
„Pafrontė“: Valstybė ir visuomenė Lietuvos pasienyje su Lenkija 1920–1939 m
Authors:   , Nekrašas Leonas
Published: May 2023

“Frontline area”: State and society in Lithuania’s borderland with Poland in 1920–1939
MULTIFUNCTIONAL NANOSYSTEMS BASED ON TWO FLUORESCENT DYES, DOXORUBICIN AND CURCUMIN
Authors:   Palladina Institute of Biochemistry of the National Academy of Sciences of Ukraine, Kyiv, Kaniuk M. I.
Published: May 2023

The aim of the work was to review the literature data regarding the prospects for the creation and use of multifunctional fluorescent two-dye nanosystems, which enable investigating the distribution of fluorescent components with significant acceleration of the study and introduction of nanomedicines into practice. Special attention is paid to the use of two substances with hydrophobic and hydrophilic properties in one nanoparticle (NP), capable of penetrating a living cell. The method of fluorescence confocal microscopy enables observation of the nanoscale dynamics of distribution and stability of drugs over time. The concomitant use of doxorubicin (DOX) and curcumin (CUR) in single nanoparticle causes synergism in the action of medical drugs, and their own fluorescence makes it possible to use them as multifunctional fluorescent nanosystems. Results. Data from the literature indicate that the use of two or more fluorescent dyes provide an advantage over other, more expensive methods when studying the penetration and distribution of NPs in living samples. The use of nanocarriers is an effective way to significantly increase the bioavailability of those drugs, which are poorly soluble in water. A promising direction of nanomedicine is the creation of complex bio-compatible multifunctional nanomaterials based on several active drugs, with the simultaneous use of their enhancers and the strategy of active targeting. Such recent structures enable targeted and controlled penetration of medicinal compounds into the sites of localization of pathological processes, reducing the toxicity of drugs to normal cells. Conclusions. The use of the fluorescence microscopy method, as exemplified by the two dyes, DOX and CUR, enables to trace the stages of interaction of loaded DOX and CUR nanoparticles with cultured cells, and their release from NPs to determine their amount and localization in organelles cells.
Longitudinal Health Status and Quality of Life in Congenital Diaphragmatic Hernia
Authors: Sreeram Isabel I. , Schnater Johannes M. , van Rosmalen Joost , Cochius-den Otter Suzan C.M. , Peters Nina C.J. , Rottier Robbert J. , Gischler Saskia J. , Wijnen René M.H. , IJsselstijn Hanneke , Rietman André B.
Published: May 2023

OBJECTIVES

To longitudinally evaluate self-reported health status (HS) and quality of life (QoL) in 8- and 12-year-old survivors of congenital diaphragmatic hernia (CDH). We hypothesized that HS would improve with age—as associated health problems tend to decline—whereas QoL would decrease, as the children start to compare themselves with peers.

METHODS

Self-reported HS and QoL of 133 children born between 1999 and 2013 who had joined our standardized follow-up program were routinely assessed at the ages of 8 and 12 with generic, internationally validated, standardized instruments. Longitudinal evaluation of total and subscale scores was performed using general linear model analyses. In addition, we compared these scores to sex- and age-specific normative data.

RESULTS

Between ages 8 and 12, boys born with CDH perceived a decline in HS (mean difference −7.15, P < .001). Self-reported QoL did not change over time in both boys and girls. At both ages, HS was significantly lower than that of healthy peers (effect size = 0.71, P = .001 for boys, and effect size = 0.69, P = .003 for girls), whereas differences in QoL were small.

CONCLUSIONS

Children born with CDH are at risk for declining HS between 8 and 12 years, but not QoL, compared with healthy peers. Given that children born with CDH tend to grow into deficits, our findings highlight the need for continued somatic and psychological assessments in adolescent and adult CDH survivors.
NUSAP1 regulates basal cell carcinoma migration, invasion and DNA damage through activation of the Hedgehog signaling pathway
Authors: Zhu Yanjun , Liu Yan , Zhang Liwen , Zeng Shihua , Xu Wen
Published: May 2023

Background

Basal cell carcinoma (BCC) is a prevalent cutaneous cancer with an increasing incidence. Nucleolar and spindle associated protein 1 (NUSAP1) is a cell proliferation-related protein that participates in the development of various cancers. However, its role and mechanism in BCC remain elusive.

Methods

The expression of NUSAP1 was detected by western blot. Gain- and loss-of-function assays were performed through the transfection of overexpression plasmid of NUSAP1 and si NUSAP1 into TE354.T cells. The role and mechanism of action of NUSAP1 in BCC were explored by cell counting kit-8 (CCK-8), colony formation, transwell, flow cytometry and western blot assays.

Results

NUSAP1 was highly expressed in TE354.T cells. Overexpression of NUSAP1 enhanced cell viability, colony forming numbers, numbers of migrated and invasive cells and the relative protein expression of RAD51, but reduced the apoptosis rate and the relative protein expression of γH2AX in TE354.T cells. Inverse results were obtained in these indicators after TE354.T cells were downregulated with NUSAP1. Moreover, the relative expression of proteins involved in the Hedgehog signaling pathway was increased by transfection of the overexpression plasmid of NUSAP1 into TE354.T cells, but decreased by the transfection of si NUSAP1 into TE354.T cells.

Conclusion

Both gain- and loss-of-function results revealed that NUSAP1 promoted proliferation, migration and invasion but attenuated apoptosis and DNA damage in BCC, which was involved in the activation of the Hedgehog signaling pathway.
The Functional Model of Legal Capacity: An Analysis of the Regulation of Legal Capacity in three Common Law Jurisdictions
Authors:   Pontifica Universidad Católica de Valparaiso, Rosas Nelson , Marshall Pablo ,   Universidad Austral de Chile
Published: May 2023

This paper introduces the developments of the functional model of legal capacity in the Common Law tradition to Spanish-speaking academic audiences. To achieve this, a brief comparison is drawn between different models to assess whether an adult lacks the necessary capacity to enter legal transactions. It is observed that, out of all these models, the functional model is the only one currently enjoying relative acceptance. For this reason, we comment on its virtues and defects. After the introductory part, this piece moves on to a study of how forensic practice in three jurisdictions that are considered examples of this legal tradition, namely England and Wales in the United Kingdom, British Columbia in Canada, and Queensland in Australia, all regulate the legal capacity of people with disabilities.
Comprehensive Sexuality Education in Latin America and the Caribbean: Where We Are and Where We Should Go
Authors:   UBA, Rinconi Liliana , Espiñeira Brenda , Guzmán Soledad ,   UBA,   UBA
Published: May 2023

In this paper we propose to provide a concept of Comprehensive Sexual Education and identify arguments based on International Human Rights Law that shoulddefine its scope and the extension of the obligations of the States in the region. In particular, we will identify five standards linked to sex education and its normative regulation; namely: a) legality, b) comprehensiveness, c) transversality, d) teacher training and e) role of families. In our opinion, these standards constitute indicators that should be considered by any public policy of Comprehensive Sexual Education. Based on this, we propose to critically analyze the regulations on sex education that exist in fifteen countries of the region. This, in order to identify aspects that could be relevant when designing a public policy of Comprehensive Sexual Education that is in accordance with international human rights standards in the matter.
Previous Contract? Precario and the Suitability of the Promise Agreement as a Defense
Authors:   Universidad Diego Portales, de la Maza Iñigo , Loayza Mosqueira Boris ,   Universidad Diego Portales
Published: May 2023

Despite its modest appearance, paragraph 2 of article 2195 of the Civil Code has been an infallible source of conflict. What interests us in this study is the existence of a promise agreement as a defense of the occupant in the face of a “precario” action. The problem is the existence of two incompatible ideas or theories in the case law. Our objective is to show these ideas and propose a solution.
Bacterial dynamics of hardaliye, a fermented grape beverage, determined by high-throughput sequencing
Authors: METİN Banu , PEHLİVANOĞLU Halime , YILDIRIM SERVİ Esra , ARICI Muhammet
Published: May 2023

Hardaliye is a traditional beverage made by fermenting red grapes with mustard seeds and sour cherry leaves in the Thrace region of Turkey. There are few studies that have determined the microorganisms responsible for hardaliye fermentation, and these are limited to lactic acid bacteria (LAB) using culture-dependent techniques. The aim of this study was to determine the bacterial dynamics of hardaliye fermentation using a culture-independent approach, high-throughput sequencing of 16S rRNA amplicons. Hardaliye was produced using the traditional method, and fermentation samples were taken at 0, 2, 4, 6, and 10 d and analyzed. During the fermentation period, pH decreased from 3.65 to 3.23. Amplicon sequencing showed that bacterial diversity was highest at 2 d, and lowest at 10 d, the final day. Although Enterobacteriaceae was the most dominant family at 0 and 2 d, Acetobacteriaceae, specifically Gluconobacter frateurii, became dominant with 50% relative abundance at 4 d, and increased its abundance to >98% at 6 and 10 d. Although a slight increase in relative abundance of 1% (0 d) to 5% (4 d) was observed in LAB, their presence was limited. To our knowledge, this study represents the first to report acetic acid bacteria in hardaliye fermentation.
Impact of Bio-Fertilizers under Supplementary Irrigation and Rain-fed Conditions on Some Physiological Responses and Forage Quality of Smooth Vetch (Vicia dasycarpa L.)
Authors: HEYDARZADEH Saeid , JALİLİAN Jalal , PİRZAD Alireza , JAMEİ Rashid
Published: May 2023

The purpose of this study was the evaluate use of bio-fertilizers to adjustment water shortage stress and improved smooth vetch (Vicia dasycarpa L.) yield under water deficit stress conditions. Thus, A 2-year experiment were performed in an agrisilviculture system of plum orchard in 2016 and 2017. In this study, the single, double and triple combined of Arbuscular mycorrhizal fungi- Rhizophagus intraradices (AMF), Azotobacter chroococcum (Az) and Thiobacillus spp. (Th) on smooth vetch plants were evaluated under rain-fed and supplemental irrigation. The results indicated that irrigated plants had more Fe and Zn nutrients than rain-fed plants. Combined use of AMF + A. chroococcum more improved the forage dry matter digestibility (DMD), total digestible nutrient (TDN), net energy for lactation (NEL), dry matter intake (DMI) and relative feed value (RFV) than plants with single inoculation. In irrigated plants, double and triple combination of AMF with A. chroococcum and/or Thiobacillus spp. improved chlorophyll-a, chlorophyll-b, total chlorophyll, RWC, TSS, AsA, and GSH while lowering proline and MDA. Rain-fed condition reduced grain yield. In conclusion, synthesis non-enzymatic antioxidant because of the combined use of bio-fertilizers (AMF, Az and Th) can reduce ROS damage and improve water deficit resistance and yield in smooth vetch rain-fed plants.
The Least Limiting Water Range to Estimate Soil Water Content Using Random Forest Integrated with GIS and Geostatistical Approaches
Authors: ALABOZ Pelin , DENGİZ Orhan
Published: May 2023

In this study, as a result of the determination of the Least limiting water range (LLWR) contents of alluvial lands with different soils, which are distributed in the Bafra Plain where intensive agricultural activities are carried out, the compression and aeration problems in the area are revealed with distribution maps. In addition, the predictability of LLWR was evaluated with the random forest (RF) algorithm, which is one of the machine learning algorithms, and the usability of the prediction values distribution maps was revealed. The LLWR contents of the soils varied in the range of 0.049- 0.273 cm3 cm-3 for surface soils. While there were aeration problems in 6.72%, compaction problems in 20.16%, both aeration and compaction problems in 0.8% of the surface soils examined in the study area, 72.32% were determined under optimal conditions. For the 20-40 cm depth, an aeration problem in the 5.88%, a compaction problem in the 28.57%, and both an aeration and a compaction problem in the 2.52% of the points were detected. In the estimation of LLWR with the random forest algorithm, the RMSE value obtained for 0-20 cm depth was determined as 0.0218 cm3 cm-3, and for 20-40 cm it was determined as 0.0247 cm3 cm-3 . In the distribution maps of the observed and predicted values obtained, the lowest RMSE value was determined by Simple Kriging interpolation methods for 0-20 cm depth and Ordinary Kriging interpolation methods for 20-40 cm. While the distribution of obtained and predicted values in surface soils was similar, variations were found in the distribution of areas with low LLWR below the surface. As a result of the study, it has been revealed that LLWR can be obtained with a low error rate with the RF algorithm, and distribution maps can be created with lower error in surface soils.
In vitro evaluation of apricot cultivars response to Pseudomonas syringae pathovars: Image processing as an alternative method
Authors: AKBABA Mustafa , HÜRKAN Kaan , KARAHAN Ahmet Erhan
Published: May 2023

Turkey, with an apricot (Prunus armeniaca L.) production amount of 833,398 tons per year, ranks first in fresh apricot production and dried apricot export in the world. Malatya, Iğdır, and Elazığ with amounts of apricot production constitute the main apricot production centers in Turkey. Many table and dried apricot cultivars have been grown in Turkey. Economically important apricot cultivars such as cv.Şalak (or Aprikoz), cv.Tebereze, cv.Ordubat, cv.Ağcanabat, and cv.Ağerik are widely grown in the Aras Valley, including Iğdır and Kağızman. In this study, DNA barcoding of local cultivars based on the ITS region was performed and their distribution was shown in the Aras Valley. The reactions of these apricot cultivars to the causal agents of bacterial canker, which negatively affect the yield and quality of apricot cultivation, were also determined. Alternative methods such as image-processing technology and CHAID analysis have also been successfully used for cultivar reaction tests. It was determined that "cv.Şalak" is the most common apricot cultivar in the Aras Valley. In addition, the Ağcanabat cultivar was sensitive to the causal agents of disease, and other local apricot cultivars were tolerant to it.
DESENVOLVIMENTO E VALIDAÇÃO DE UM DISPOSITIVO PARA MENSURAÇÃO DA FLEXIBILIDADE POR MEIO DO ACELERÔMETRO EM CRIANÇAS
Authors: Oliveira Marilene Ferreira de Lima , Silva Alessandro Pereira da , Silva André Roberto Fernandes da , Moura Luan de Almeida , Scardovelli Terigi A. , Martini Silvia C. , Boschi Silvia Regina Matos da Silva
Published: May 2023

Os objetivos deste estudo foram desenvolver e validar um dispositivo computadorizado para mensurar a flexibilidade articular; mensurar a flexibilidade em crianças no ensino fundamental de 8 a 10 anos por meio do banco de Wells; comparar os dados alcançados pelo banco de Wells e o dispositivo computadorizado desenvolvido no presente estudo e avaliar a usabilidade do dispositivo. Participaram desta pesquisa 215 voluntários, com idade de 8 a 10 anos, sendo 63,72% (137) do sexo feminino e 36,28% (78) do sexo masculino, devidamente matriculados em uma instituição de ensino na região do Alto Tietê. Para coleta de dados, os voluntários realizaram o teste de flexibilidade utilizando o banco de Wells e o dispositivo computadorizado desenvolvido nessa pesquisa para avaliar a flexibilidade.O dispositivo foi confeccionado numa impressora de tecnologia de impressão 3D. Foi realizada uma avaliação da usabilidade com 15 professores de Educação Física para o produto desenvolvido através da interação de usabilidade baseada no formulário System Sustainability Scale (SUS) que contém 10 questões de múltipla-escolha. Os dados obtidos por medidas objetivas determinadas foram avaliadas quanto à frequência, média e desvio padrão. Foram seguidas como médias aritméticas das três medidas realizadas em cada etapa. Para investigar realizou-se os testes de Mann-Whitney e de Kruskal-Wallis e a tradução de Spearman. Para todas as análises foram consideradas diferenças significativas p<0,05.Conclui-se que o dispositivo computadorizado para medir a flexibilidade articular é capaz de avaliar em graus a amplitude de movimento,
A Preliminary Report on the Safety and Efficacy of a Novel MaiLi HA Filler for Facial Correction of Wrinkles, Folds, Volume and Lips
Authors: P Micheels , M Poiraud
Published: May 2023

Introduction: The principal author was given the opportunity to assess new hyaluronic acid filler, first before its European Commission labeling during clinical investigations in France, and then after its European Commission labeling in his clinical practice in Geneva, Switzerland. This hyaluronic acid gel benefits from the world’s first patented OxiFree™ technology. This article sought to present preliminary safety and efficacy data from the first private patient series treated in Geneva with this cross-linked hyaluronic acid gel, called MaiLi. Material and methods: Like most of its competitors, MaiLi is available in various variants, including gel for filling fine wrinkles, for deeper wrinkles, folds, and for lip enhancement, in addition to gels for volumizing indications. This cohort study encompassed patients from the authors’ private esthetic clientele in Geneva, Switzerland. Depending on the indications, the injections were performed according to previously described techniques, ranging from the “blanching technique” to deeper injections. Results: Between January and November 2021, overall 45 patients aged 56 years on average were injected MaiLi gels, according to the areas they wished to be treated, with a follow-up period ranging from a few days to 12 months. Based on our current dataset, we confirm that MaiLi fillers have proven very safe, causing no unexpected undesirable effects. The gel’s hold over time related to its remarkable projection capacity was excellent, resulting in quite natural outcomes and a perfect integration into the tissues. These beneficial effects were still evident at 1-year follow-up. Conclusion: The MaiLi hyaluronic acid fillers proved to be well tolerated and safe, with long-lasting effects. Remarkable properties revealed in this follow-up were their projection capacity and suppleness, as well as their ease of use and longevity, resulting in full patient satisfaction. No relevant undesirable effects were observed. There were no edematous reactions following the injections, nor were there any lymphatic circulation disorders.
The Effects of YouTube Corporate Channel Subscription Motivation on Corporate Image: Focusing on the Mediating Effect of Social Presence
Authors:   The Korea International Trade Research Institute, Youm Dong-Sup
Published: May 2023

Purpose – Nowadays, many enterprises are expanding communication with customers by opening their own YouTube channels. This intensive medium exceeds the effect of Legacy Media in corporate marketing. Based on the background seen above, this study proceeded to investigate a social presence’s mediating effect in relationship between subscription motivation for YouTube corporate channels and corporate image. This is because social presence has been known as an important variable that mediates the communication process between information providers and consumers in today's social viewing environment. Design/Methodology/Approach – An online survey was conducted, and data from 435 individuals subscribing to corporate YouTube channels were used for analysis. Findings – According to the research hypothesis verification result through SPSS Process Macro, a playful subscription motivation for YouTube corporate channels in relation with corporate image was verified, social presence showed a fully mediating effect, and professionalism and recency subscription motivation showed partial mediation. Research Implications – The following results imply that taking notice of the importance of user subscription motivations and social presences is important to corporations that operate corporate channels on YouTube to improve corporate image.
Private Firm Repayment Vulnerabilities and Adverse Economic Conditions
Authors: Darst Matthew , Zhang Mary
Published: May 2023

This note extends to private firms an analysis of the impact of macroeconomic conditions on corporate interest coverage ratios (ICRs), a measure of repayment risk developed by McCoy et al. (2020). Our analysis is complimentary. We utilize unique data on private-firm balance sheets obtained through the Federal Reserve's Comprehensive Capital Analysis and Review (CCAR) process and evaluate the impact of updated and new macroeconomic projections on the distribution and path of corporate interest coverage ratios.
T.V. PheroLure® : Volatile emission by semiochemical lures and the impact thereof on the volatile profile of a commercial tomato field
Authors: Van Tonder Aletta J , Nortjé Gerhardus P , Botha Ben M
Published: May 2023

Pheromone-based or semiochemical lures for insect detection and monitoring in agriculture is common practice. Many countries exempt these devices from regulatory requirements,  but not South Africa. The question arises whether the pheromone/semiochemical lures influence the naturally occurring compounds significantly, to justify concern for human toxicity and ecotoxicity. T.V. PheroLure® is a novel five-component lure developed by Insect Science (Pty) Ltd. used for monitoring African bollworm, Helicoverpa armigera (an important insect pest on tomatoes). T.V. PheroLure® is a volatile organic compound (VOC) blend impregnated in a polyethylene bulb. The influence of T.V. PheroLure® on the volatile profile of a tomato field was evaluated in a commercial growing area of South Africa. Tomato VOCs were collected before, during and after the application of six T.V. PheroLures® in yellow bucket funnel traps randomly distributed over 1 ha. VOCs were collected from planting until harvest (22 weeks) at five randomly selected sites. Collection also took place in adjacent tomato fields where no T.V. PheroLure® was applied. The constituents of T.V. PheroLure® had no significant influence on the naturally occurring VOCs observed in the tomato field. The results suggest that the concern for toxicity and ecotoxicity is unjustified when using semiochemical devices for monitoring purposes. The natural physiology of the plant, rather than T.V. PheroLure®, influenced the VOCs observed in a tomato field.
Writing in Water
Authors: Mikulić Borislav
Published: May 2023

The book contains a collection of historical and systematic studies on metaphors and related topics, in German and English, that were first drafted as initial elaborations of the author's research project on the historical and systematic philosophy of language at the University of Tübingen in two periods (1992–1994 and 1996–1999). About half of the essays have been published before in some form but for this edition they have been improved upon or revised to fit better with the book as a whole. The groundwork for this collection was laid in the mid-1990s by the first review paper, written in Croatian, devoted to the topic. The papers collected in this volume are only in German and English. Grouped in sections, they do not represent different language versions of the same text but provide individual elaborations of interrelated topics in German or in English. Each begins with different problems of both historical and systematic nature and each ends, hopefully, by contributing new points to their respective topic. As a result, every chapter can be read either as an alternative to the paper it is paired with in the respective section or as a supplement to other texts.
Analisis Pelaksanaan Hukuman Alternatif dalam Kes Khalwat di Negeri Selangor
Authors: Dato’ Kamarudin Abdul Fattah , Darus Muhammad Mustaqim , Yahya Mohamad Azhan , Mohd Shariff Ahmad Azam
Published: May 2023

Selain daripada hukuman sedia ada, mahkamah syariah turut boleh menjatuhkan hukuman alternatif. Kajian ini bertujuan menganalisis pelaksanaan hukuman alternatif dalam kes khalwat oleh mahkamah syariah di negeri Selangor. Kajian ini menggunakan kaedah kualitatif dalam penganalisisan isu berkaitan. Kajian ini ditumpukan kepada bentuk-bentuk penghakiman dalam kes jenayah khalwat yang dijatuhkan oleh semua mahkamah rendah syariah di negeri Selangor dengan melihat kepada justifikasi penghakiman samada berbentuk punitif mahupun rehabilitatif. Data dikumpul dengan mengguna pakai kaedah kajian kepustakaan. Data primari dan sekunder berkaitan hukuman alternatif dalam kes khalwat dikumpul bagi mengenal pasti permasalahan serta persoalan kajian. Temubual turut dijalankan ke atas hakim mahkamah rendah syariah dan pendakwa syarie di negeri Selangor, pegawai penjara Malaysia dan pegawai pusat koreksional Malaysia dalam bentuk berstruktur dan separa struktur. Kajian mendapati kelompangan dalam peruntukan Enakmen Jenayah Syariah dan Enakamen Tatacara Jenayah Syariah berkaitan pelaksanaan hukuman alternatif. Kajian ini mencadangkan agar pelaksanaan peruntukan undang-undang terbabit diperincikan dan diperkemaskan. Adalah diharapkan agar analisis kajian akan berupaya menangani permasalahan berkaitan pelaksanaan hukuman alternatif di mahkamah syariah. Semoga kajian ini juga berupaya memperkasakan pelaksanaan hukuman alternatif di mahkamah syariah dan seterusnya membantu mahkamah dalam membuat penghakiman.
A rare case of diaphyseal fractures of the shin bones in a child when jumping on a trampoline. Ways to prevent expert errors using complex analysis of radiography data and case materials: A case report
Authors: Li Yulia B. , Vishniakova Marina V. , Klevno Vladimir А.
Published: May 2023

Given the importance of childhood injuries in the structure of common problems associated with childrens health, it is important to determine the exact mechanism of fractures, particularly diaphyseal fractures of the shin bones, during the examination because the specification of the mechanism for the formation of bodily injuries leads to the actual origins of injuries and allows further development of a set of preventive measures to prevent the occurrence of these situations. Moreover, it sometimes allows the defendants to accurately distribute the burden of responsibility for what happened.
In the presented expert case, the circumstances of bodily injury described by the subject and her legal representative were inconsistent with the type and nature of fractures received while trampoline jumping and the video recording from the surveillance camera did not provide complete information about the specific conditions of injury. A detailed analysis of the results of shin bone radiography, including determining the morphological features of fractures and their nature, and a frame-by-frame study of the presented video recording.
The diaphyseal fractures of the shin bones of atypical localization for a trampoline injury detected in a child could serve as a source of expert errors in determining the mechanism of their occurrence; however, a thorough, comprehensive assessment of all objects for examination, such as medical documents, including X-ray data and case materials, taking into account the age-specific morphology of the bone tissue of the child, enables to determine the exact mechanism of the occurrence of fractures.
Organ-preserving treatment in progressive cervical pregnancy. A clinical case
Authors: Sulima Anna N. , Gunar Zoya V. , Adamov Alexandr M. , Gordeychik Andrey E. , Mkrtchian Azat A. , Davydova Aleksandra A. , Tkacheva Nataly Yu.
Published: May 2023

This article describes a rare clinical case of progressive ectopic pregnancy in the cervix in a female patient of reproductive age, the incidence of which is less than 1% of all ectopic pregnancies. The exact etiopathogenetic mechanism of cervical pregnancy is still unknown. Misdiagnosis of cervical pregnancy can lead to a fatal outcome with massive bleeding and is associated with the risk of hysterectomy and complete loss of fertility in patients of reproductive age.
This article presents the results of a pathoanatomical study confirming the diagnosis and adequacy of the performed therapeutic measures. We demonstrated the complexity of diagnosing this pathology, as well as the possibility and conditions for performing an organ-preserving surgery. The presented clinical case will allow doctors of various specialties to know more about this rare form of ectopic pregnancy, to suspect and successfully diagnose cervical pregnancy in the early stages of gestation, which will avoid or reduce the development of severe and sometimes life-threatening complications.