bluuebunny/crossref_metadata_2025 huggingface dataset:
Chemical Evaluation of a Nori-Like Product (Geluring) Made from the Mixture of Gelidium Sp. and Ulva Lactuca Seaweeds
Authors: ERNIATI ERNIATI , ZAKARIA FRANSISKA RUNGKAT , PRANGDIMURTI ENDANG , ADAWIYAH DEDE ROBIATUL , PRIOSOERYANTO BAMBANG PONTJO , HUDA NURUL
Published: December 2018

Dry sheet food products or nori-like products can be produced from the mixture of Gelidium sp. and Ulva lactuca seaweeds, which is called geluring. Making geluring involves heat application that may influence the chemical composition of the product. The goal of this study was to evaluate the chemical characteristics of geluring by measuring proximate composition; dietary fiber, total phenolic, and flavonoid contents; and antioxidant activity(by DPPH analysis)of geluring and compare the values to those of the raw materials. Three types of geluring were prepared following commercial nori preparation procedures with some modifications: P1 (unseasoned), P2 (seasoned), and P3 (seasoned and roasted).The proximate composition of geluring products and raw materials differed significantly(P<0.05). Geluring fiber contents were not significantly different (P>0.05) among P1 (29.19±0.26%), P2 (29.42±0.66%), and P3 (29.83±0.11%), but these values differed significantly (P<0.05) from those of the raw materials. The total phenolic content, flavonoid content, and DPPH activity of P2geluringwere 1.38 mg GAE/g, 1.11 mg QE/g, and 61.23%, respectively, which were significantly (P<0.05) higher than those of P1 and P3 but lower than those of the raw materials. These results suggest that geluring processing might negatively impact the chemical composition of the products, but they still have high antioxidant activity and dietary fiber content and thus have potential for utilization as a functional food product.
New genetic tool to predict risk of adult MI in childhood
Authors: Palmer Sarah Jane
Published: December 2018

Just as the 100,000 Genomes Project is wrapping up after hitting its target to sequence 100,000 genomes by the end of 2018, researchers have created the Genomic Risk Score to identify people at risk of coronary heart disease. Sarah Jane Palmer reports on the new tool that can be used in children to highlight and address risk from earlier on, so they can live longer and healthier lives as adults
Cross-species milestone with pig-to-baboon heart transplant
Authors: Palmer Sarah Jane
Published: December 2018

In this monthly feature, Sarah Jane Palmer delves into topical news, the latest research and what the experts are saying on subjects related to cardiology and cardiac nursing practice.
Leading the integration of physician associates into the UK health workforce
Authors: Edwards Luke D , Till Alex , McKimm Judy
Published: December 2018

The introduction of physician associates into the UK health workforce is one of the most significant examples of potentially disruptive innovation in many years, and lessons can be learned from research into the introduction of advanced nurse practitioners. Positive, forward-looking health-care leadership is required at all levels to ensure the successful integration of physician associates into the UK workforce.

This review found that organizational culture had an enormous impact on the introduction of advanced nurse practitioners and likewise will affect the integration of physician associates. The most effective strategies facilitated interprofessional, collaborative, collective and inclusive leadership and promoted high staff engagement, the development of proficient interprofessional practitioners, and a clear vision for collaborative practice. In terms of physician associates, such an approach will improve interprofessional and collaborative practice and create the supportive, motivated environment needed to facilitate the introduction of physician associates.
Treatment Outcome Analysis of Artemisinin based Therapy in Plasmodium falciparum Infection: An Observational Study
Authors: Amita Priya D. , Meena Kumari K. , Varma Muralidhar , Mohanbabu V. Amberkar , Adiga Shalini , Balaji O. , Vanishree R.
Published: December 2018

Currently, the preferred treatment for chloroquine (CQ) resistant Plasmodium falciparum (Pf) is Artemisinin combination therapy (ACT). Our aim was to assess the artemisinin based treatment outcomes in patients with Plasmodium falciparum infection. Patients with falciparum infection from a tertiary health care centre in South India were enrolled in this study. It was a non-randomised observational study .The data regarding peripheral blood smear, complete blood count, liver, renal function tests and the treatment given was documented at admission and on the day of discharge. Patients with uncomplicated falciparum malaria were most common. Artesunate and doxycycline was the most common combination used at our centre (54.6%) followed by artemether –lumefantrine. All patients had peripheral smear negative for Plasmodium falciparum parasite by the end of treatment. There was improvement in blood count,liver and renal function tests. Artemisinin based combination therapy was effective in treatment of falciparum malaria.
The Indifference of Daily Wearing of Corrective Linen in Relation to Platelet Activity in Women of Second Adulthood with First Degree Hypoid Obesity
Authors: Bikbulatova A.A. , Medvedev I.N.
Published: December 2018

Despite the long and systematic efforts of modern medicine, obesity in women in developed countries is still a fairly common condition. Particular attention to this problem is caused by an increase in recent years in the number of cases of this pathology among women of working age who do not have the opportunity to regularly visit fitness halls and comply with various dietary restrictions. In this connection, the problem arises of cosmetic correction of their figures with minimal costs and efforts on the part of women. An exit from the given situation can be wearing corrective clothes, capable to lower volumetric sizes of a body by mechanical influence on it in problem sites. In the work, an evaluation was made of the safety of prolonged wearing of the author's version of the trousers, taking into account hematological and haemostasiological indices. It was found that in women with obesity of grade 2, who received this correction, there was a persistent retention of the measured values ​​within the limits of the norm. The use of the author's version of corrective clothing in women with obesity was accompanied by a visual decrease in the size of their body at the place of wearing the used product. At the same time they had a stably normal level of platelet aggregation, corresponding to the values ​​of control. The obtained results allow to consider the author's corrective clothing as a full and safe component of visual correction of obesity manifestations in women.
Evaluation of Anticariogenic Efficacy of Pomegranate (Punica Granatum) Pericarp Extract as Natural Mouth Rinse: An In Vitro and In Vivo Study
Authors: Pinni Jyothsna , Sankar Avula J.S. , Mukthineni Sridhar , Bandi Sujatha , Gokul Thulasi
Published: December 2018

Plant materials were known as source of new antimicrobial agents. Many efforts have been made to develop alternative mouth rinses from natural products which are safe, easily available and substitute the standard pharmaceutical remedies. Thus, considering the therapeutic value of pomegranate fruit, the present study was designed to compare the antimicrobial efficacy of aqueous extract of Pomegranate pericarp and commercially available Chlorhexidine mouth wash against caries causative microorganisms both in vitro and in vivo. To evaluate the antimicrobial efficacy of pomegranate pericarp extract (PPE) against Streptococcus mutans (S.mutans) and to determine its usefulness as anti caries mouth rinse. In vitro antimicrobial efficacy was evaluated by disc inhibition zone method and broth dilution assay considering minimum inhibitory concentration of PPE. In vivo evaluation was done as a randomised controlled trial which included thirty children aged between 6-12 years. They were divided randomly into 3 groups of ten each and subjected to different mouth rinses - Group I: PPE mouth rinse, Group II: 0.2% Chlorhexidine mouth rinse and Group III: Distilled water (control). The salivary samples which were collected before and after (5 minutes) mouth rinsing were inoculated on Mutans Sanguis agar and the bacterial count was calculated.Statistically significant decrease in salivary S.mutans count was observed in group I and II compared to group III after mouth rinsing. However, there was no statistically significant difference between groups I and II. PPE mouthwash was effective in reducing the salivary S.mutans count and was comparable to chlorhexidine mouth rinse. Hence PPE mouth rinse may be considered as a potential anti caries mouth rinse.
In vitro and In vivo Evaluation of Potential Anti Diabetic Efficacy On Cassia Auriculata Flowers
Authors: Nagarajaperumal G. , Idachristi V.E. , Karpakavalli M. , Mohan S.
Published: December 2018

Diabetes mellitus (DM) is most significant health problem in various developed and developing countries due to alteration of various clinical and pathological factors. Current work was intended for examine in vitro and in vivo anti diabetic competence of Cassia Auriculata flowers and its phytochemical analysis. The inhibitory effects on carbohydrate digestive enzyme α- amylase interaction with various extracts of Cassia Auriculata were contrast with acarbose. Hypoglycemic activity was executed with standard as a glibenclamide. Study indicated ethanolic extract showed higher action on α- amylase inhibition with assessment of IC50 value; 43.6%. Based on the above results of in vitro studies were used to selected ethanolic extract of Cassia Auriculata flower used for further study. Results of animal studies indicated that the ethanolic extract of C. Auriculata has shown dose dependent action (200 mg/ kg (1.20±0.91↓) and 400 mg / kg (4 ± 0.01↓) when compared to control and standard drug treated groups. Our study confirmed to ethanolic extract work through the α- amylase inhibition mechanism. Our view bioactive constituents confirm anti diabetic capacity and afford methodical source for validation of Cassia Auriculata flowers in ayurvedic formulations on diminution of DM prevalence.
Laparoscopy Diagnostic and Bilateral Gonadectomy in a Patient with Complete Androgen Insensitivity Syndrome (CAIS) – A Rare Case of Primary Amenorrhoea with 46XY Karyotype
Authors: Adnyana IB Putra , Chandragiram TGN , Negara Ketut Surya
Published: December 2018

Bilateral laparoscopic gonadectomy is reported as an operative procedure of removing the intraabdominal gonads in individuals with complete androgen insensitivity syndrome (CAIS). We present a case of 18 year old patient who had history of primary amenorrhea. The clinical evaluation shows a female phenotype, excellent breast development, absence of hair in the groins and axillary areas and short blind vagina. In ultrasonographic examination uterus was absent. Hormonal assay showed elevated serum testosterone levels of 1,037 ng/dL. A karyotype was also performed which revealed a 46 XY. Laparoscopy diagnostic revealed absence of internal genitalia except bilateral gonads appearing as testes. The testes were removed to avoid the risk of malignancy. Histopathological examination revealed that both the masses were composed of testicular tissue. Laparoscopy allows to clearly identify, locate as well as gonadectomy in the same time. This approach results in rapid recovery with minimal blood loss and should be considered for all patient with intraabdominal gonads.
Surgical Managementof Brachial Plexus Injury
Authors: Tjokorda Mahadewa
Published: December 2018

Brachial plexus injury is an injury of the shoulder nerve that often happens in young adult. It has a relatively high disability rate. The clinical outcomes of brachial plexus surgery to date are still disappointing, especially for the total plexus injury that affects the C5-T1. However, expectations remain with the advance of technology and more recent surgery techniques, specifically the emergence of distal neural transfer. This was a retrospective study with 9 brachial plexus injury patients, since 2012-2017. The aim to evaluate surgical strategies outcome of the management. The principle of handling brachial plexus palsy when conservatives fail is surgery, like autologous graft, neural transfer, neurolysis, and direct suture. Improvement of elbow flexion is the utmost priority and shoulder stabilization as well. Various techniques are used lately, but to date, they have not been able to improve the functioning of the patient's fingers.
Salivary pH, Flow Rate and Streptococcus mutans Count in Relation to Oral Health Statusamong Colored Eyes Adolescentsin Baghdad/Iraq
Authors: Fahad Ali Hadi , Al-Huwaizi Raed Faisal , Al-Rubbaey Yamama A. , F. Alhuwaizi Abbas
Published: December 2018

Differences in susceptibility to dental caries occurs even under the similar, controlled conditions because of genetic variations, certain environmental factors are potentially more cariogenic for some individuals than for others. Salivary constituents differences may cause variation in caries susceptibility. This study was conducted to assess the salivary pH, flow rate and streptococcus mutans count in relation to oral health status among colored eyes adolescents. The study group included all 85 colored eyes adolescents from 6 secondary schools, while control group contained 85 brown eyes adolescents selected randomly from the same schools (12-15 for both groups, only males). Decayed, missing and filled teeth (DMFT), plaque (PlI), Gingival (GI) and calculus (CI) indices were used to measure oral health status for both groups. Salivary samples collection was done in the morning at least one hour after breakfast, then normal saline was added to have tenfold dilutions, to assess the total colony counting of the caries related microorganisms (streptococcus mutans), after that inoculation was done in the special selective media (Mitis-Salivarius-Bacitracin agar). Counting of bacterial colonies were estimated by the aid of dissection microscope. Salivary pH and flow rate were measured directly. The data of present study was analyzed using SPSS version 21. The median and mean rank values for DMFT, PlI, GI and CI indices were higher in study group than control group with high significant differences with regard to DMFT and PlI. A strong positive correlation was recorded between DMFT and PlI, GI, CI in both groups. Salivary pH and flow rate were lower in study compared to the control group (statistically significant difference with salivary flow rate). Higher mean value of salivary streptococcus mutans count among study group compared to control group with statistical significant difference. Dental caries experience and streptococcus mutans count were higher in colored eyes adolescents than brown eyes adolescents. Oral hygiene and salivary flow rate were lower in study group than control group.
Antifungal Potential of Aqueous Extract of Some Traditional Plants on Microsporum Gypseum
Authors: Sudan Puneet , Singh Jitender
Published: December 2018

The aqueous extracts of Azadirachta indica, Trigonella foenum graecum, Allium sativum, Cinnamomum tamala, Capsicum annum were used to test their antifungal properties against the keratinophilic fungus Microsporum gypseum. Plant aqueous extracts were taken at two different concentrations of 5% and 10%. The present study revealed that Allium sativum and Capsicum annum at 10% conc. had more potent antifungal potential as compared to all the other extracts followed by Azadirachta indica, Trigonella foenum graecum and Cinnamomum tamala.
Administration of Honey and Royal Jelly Ameliorate Cisplatin Induced Changes in Liver and Kidney Function in Rat
Authors: Waykar Bhalchandra Baburao , Ali Alqadhi Yahya
Published: December 2018

Although cisplatin is an effective drug, its clinical use is limited because of its side effects. Honey and royal jelly are natural antioxidants that can be extracted from honey bees. The aim of this investigation is to study the ameliorative role of both honey and royal jelly against cisplatin induced changes in levels of liver and kidney function biomarkers in rat. Male wistar albino rats of almost same age and weight were divided randomly into four groups. Group I: (control group) rats were given 0.9% saline. Group II; (cisplatin group) rats were injected by cisplatin (7mg/ kg/ day) intraperitoneally for 15 days. Group III; (Honey and Royall jelly group) rats were fed orally honey (500 mg/kg/day) with royal jelly (100mg/kg/day) for 15 days. Group IV; (cisplatin and honey with royal jelly group) rats were injected cisplatin (7mg/kg/day) intraperitoneally and fed orally honey (500mg/kg/day) with royal jelly (100mg/kg/day) daily for 15 days. At the end of experiment, blood was collected and serum was got by centrifugation at 3500 rpm. Serum obtained was analyzed for liver function test by estimating ALT, AST, ALP, total bilirubin, albumin, and total protein and kidney function test by estimating creatinine, urea, and uric acid levels. Administration of cisplatin to rats (Group, II) leads to a significant increase in serum ALT, AST, ALP enzyme activity, while the values of total bilirubin, total protein and albumin were significantly decreased as compared to control. Oral supplementation of royal jelly and honey to rats (Group, III) showed comparable enzyme activity of ALT, AST, ALP and values of total bilirubin, total protein and albumin to control. In the rat group that were administered honey and royal jelly in association of cisplatin (Group, IV) improvement was observed in liver function biomarkers. Cisplatin administrated rats (G, II) shows a significant increase in the values of kidney function biomarkers like creatinine, urea and uric acid compare to control. Oral supplementation of royal jelly and honey treated to rats (Group, III) showed comparable values of creatinine, urea and uric acid to control. In the rat group that were administered honey and royal jelly in association of cisplatin (Group, IV) improvement was observed in kidney function biomarkers. The study found that combined administration of honey and royal jelly attenuated the cisplatin induced alterations in liver and kidney function biomarkers, because honey and royal jelly are free radical scavengers, lipid peroxidation inhibitors and anti-inflammatory effects and hence are recommended during the cisplatin chemotherapy.
Compared to Conventional Dressing Techniques, Tranexamic Acid Injection Provide Better Surgical Outcomes in Spinal Fusion Surgery
Authors: Fauzi Ahmad , Moelyono Adam , Tobing S. Dohar
Published: December 2018

The use of mechanical and chemical hemostatic control techniques in spinal fusion surgery is common in Indonesia. However, there has been no study comparing the two in a single clinical trials. This study aims to find out which best of tranexamic acid injection, a bulky compression dressing and a standard dressing in providing surgical outcomes in spinal fusion surgery. Thirty patients were grouped into three, 10 patients each. To Group 1, tranexamic acid at a dose of 500 mg/ml was administered pre operation and 2 hours later. For Group 2, a bulky compression dressing was performed by covering the surgical wounds with a low-adherent dressing, overlaid with four layers of sterile gauze and then sealed with a conformable adhesive retention tape. Standard dressing was applied to the patients of Group-3 using the same type of bandage and adhesive tape given to the Group-2, but only overlaid with two layers of sterile gauze. There is no statistical difference among trials groups for preoperative (P > 0.220) and postoperative (P > 0.380) hemoglobin levels and the level of perioperative blood loss (P > 0.110). With respect to number of transfusion required, the tranexamic acid group was significantly lower compared to the standard dressing group (P = 0.018). No abnormality of wound seen in all three trials groups and only 2 patients of bulky compression dressing group reported experience of headache. In conclusion, tranexamic acid is better to promote hemostasis compared to conventional dressing techniques.
On the political economy of privacy in communities that include both friends and foes
Authors: Congleton Roger D.
Published: December 2018

This paper develops a conceptual framework for analysing privacy issues. Neither privacy nor fame are ordinary economic goods. The demand for both are derived from their associated consequences. In some settings privacy is useful, but in others not. When applied to privacy-relevant public policies, the analysis indicates that there are significant differences between the privacy-relevant policies of authoritarian and democratic regimes. The analysis also demonstrates why technology affects public support for privacy-relevant policies. For example, a shift from ‘stove pipe’ to ‘big data’ tends to reduce electoral support for government expenditures on detection activities.
Imperfect democracy and economic freedom
Authors: Murphy Ryan H.
Published: December 2018

Recent research has explored the determinants of economic freedom, an important measure of institutional quality. Concurrently, some scholars have posited a negative relationship between the quality of economic institutions and democracy, specifically at very high levels of democracy. This paper disaggregates the Polity IV index into a vector of 20 dummy variables to explore how differing degrees of democracy and autocracy may impact economic freedom, thereby leaving open the possibility for levels of democracy modestly less than perfect democracy to have better effects on economic freedom. This paper will also consider the Vreeland re-estimate of the Polity IV index, the Grundler-Kreiger measure of democracy, the use of a quadratic term, and quantile regression. The weak evidence that is found points to a modest positive relationship between democracy and economic freedom, with little evidence that marginally less democracy will subsequently lead to more economic freedom.
The productive-unproductive puzzle in Adam Smith: what have we missed?
Authors: Mehta Nimai M.
Published: December 2018

This paper returns to Adam Smith's much maligned distinction of productive versus unproductive labour to flesh out a dimension of capital productivity that has been missed by the modern theory of production and welfare. The puzzle lies in Smith's use of a binary measurement scale to suggest opposing productivity, and household welfare outcomes obtained with a durable versus non-durable good. A durable good generates a permanent fund of labour savings and service spillovers over time. This dimension of productivity exists separate from, and beyond, any marginal productivity attributed to capital or labour services within the neoclassical production function. And, it forms the basis of improvements in household welfare that Smith described in the Wealth of Nations – in terms of continual net increases in the consumption-production possibility frontier enjoyed by the household, as a result of service spillovers obtained with a durable good over time. In contrast, no such spillovers are obtained with a non-durable good. A preference-bias for non-durable goods, instead, proves to be welfare-reducing – by having households under-invest and/or fail in maintaining the accumulated stock of durable-goods-as-capital. Both lead to a loss of production-consumption possibilities available within the household economy. An exploration of Smith's concern with ‘unproductive labour‘ brings back into focus the broad set of behavioural traits and ethicallegal restraints that underlie economic progress and have been missed by neoclassical theory.
James M. Buchanan: from Chicago to Virginia and Knight's influence on Buchanan
Authors: Forte Francesco , Brady Gordon L.
Published: December 2018

This paper examines the influence of Frank Knight on James Buchanan during the latter's time as a student at the University of Chicago through to the successive periods of his life. We maintain that Knight's approach to economics and politics – in which individual freedom, (institutional) rules of the game and ethical rules are all paramount in explaining behaviours in both the market and the public sector – strongly influenced Buchanan's interdisciplinary intellectual enterprise. In this context, we stress Knight's influence on Buchanan's catallactic approach to both the formation of rules at the constitutional level and ordinary level, as well as for the behaviour of individuals interacting in the market and public sector. In this inheritance, the relevance of ethical values for economic progress and protection of a good, free society increased during Buchanan's last period of scientific research, with positive and normative levels always carefully distinguished, as in the Frank Knight tradition.
DANIELA RIGATO (2013). Gli dei che guariscono. Asclepio e gli altri.
Authors: D'Encarnação José
Published: December 2018

Bologna: Pàtron Editore, 164 pp.
Ecclesiastical sigillography in the Czech Republic – current situation, themes and perspectives
Authors: Bolom-Kotari Martina
Published: December 2018

Sigillography is regarded in the Czech Republic as a traditional academic discipline. The history of the field shows, however, that it has yet to welcome the production of a seminal, far‑reaching work. In earlier time, ecclesiastical sigillography was largely neglected, seeing little development until recent decades. The first analytical studies are now appearing which attempt to interpret sigillographical materials in a broader historical context. Researchers are now also turning their attention to modern materials, giving rise to specific terminological and methodological difficulties. This study offers a brief outline of developments in sigillography in the Czech Republic, and particularly ecclesiastical sigillography. In this specific case, it describes the research objectives and the questions beingasked, while outlining proposed solutions.
Andrea Mariana Navarro, Ciudades de Andalucía: paisajes e imágenes. Siglos XIII‑XVII, Madrid, Comité Español de Ciencias Históricas / Editorial Dykinson, 2017, 402 p.
Authors: Feio Rodolfo Petronilho
Published: December 2018

https://doi.org/10.14195/0870-4147_49_14
Tutankhamon em Portugal: relatos na imprensa portuguesa (1922-1939). A revista Diónysos, Humberto Pinto de Lima e Tutankhamon
Authors: Sales José Das Candeias , Mota Susana
Published: December 2018

A descoberta do túmulo de Tutankhamon, em 1922, foi noticiada pela imprensa internacional, de forma inusitada, tornando este faraó e o arqueólogo responsável pelo achado sobejamente conhecidos de milhões de leitores. Ironicamente, Tutankhamon era um dos faraós menos conhecidos da história egípcia e Howard Carter um arqueólogo sem créditos firmados que, assim, literalmente de um dia para o outro, passaram da obscuridade para as páginas dos periódicos. Na imprensa portuguesa, a partir de 1925, a revista Diónysos reservou espaço em três números para pequenos ensaios, genericamente intitulados “Quem era Tutankhamen”, da autoria de Humberto Pinto de Lima, então assistente de Ciências Históricas da Faculdade de Letras da Universidade do Porto. Neste artigo apresenta-se uma análise detalhada desses textos, relevando o domínio científico das problemáticas pelo Autor e o seu contributo para a discussão dos temas de história egípcia entre nós.
Notícias sobre situações meteorológicas de risco em Portugal na Gazeta de Lisboa (1715-1762)
Authors: Silva Luís Pedro
Published: December 2018

A atenção que a imprensa escrita prestou – e continua a prestar – aos eventos hidrometeorológicos, principalmente aos episódios extremos, faz deste tipo de publicação uma fonte incontornável no estudo do clima e dos estados do tempo. A quantidade e a relativa qualidade das notícias, muitas vezes associadas a descrições pormenorizadas dos fenómenos e dos prejuízos causados, e a sua alargada abrangência geográfica, são apenas algumas das vantagens que podemos encontrar neste tipo de publicação. No presente estudo, pretendemos analisar detalhadamente um dos principais periódicos portugueses de carácter noticioso e um dos mais duradouros da história da nossa imprensa: a Gazeta de Lisboa. Propomos um estudo qualitativo e quantitativo de todas as notícias de interesse meteorológico referentes a Portugal, publicadas neste periódico entre 1715 e 1762, procurando, por um lado, definir padrões de percepção e variáveis de registo e, por outro, comprovar a importância da imprensa no estudo do clima e dos estados do tempo.
PÉCOUT, Thierry (dir.) (2017). De l’autel à l’écritoire : genèse des comptabilités princières en Occident, XIIe-XIVe siècle. Paris: Éditions De Boccard, 476 pp. ISBN: 978-2-7018-0367-8.
Authors: De Campos Maria Amélia Álvaro
Published: December 2018

https://doi.org/10.14195/1645-2259_18_22
Sermones políticos y audiencia. Una revisión crítica de la predicación en vísperas de la Guerra de las Comunidades de Castilla
Authors: Herrer Hipólito Rafael Oliva
Published: December 2018

El artículo efectúa una revisión crítica de la predicación política mendicante en vísperas de la Guerra de las comunidades y en particular de los sermones pronunciados en Valladolid. El análisis clásico de estos acontecimientos está basado en errores que impiden percibir las verdaderas implicaciones subversivas de estos sermones políticos. Un nuevo análisis de estos acontecimientos permite además incorporar elementos que son objeto de reciente atención historiográfica, como las relaciones entre predicación y audiencia a partir del análisis de la recepción del discurso. En último término, el artículo permite desvelar el protagonismo de los predicadores en la difusión de conceptos y lenguajes políticos.
“Almoços, lunchs, jantares e ceias”: os serviços de restauração em Lisboa à luz dos anuários comerciais (1871-99). Tipologias, serviços e produtos
Authors: Gomes João Pedro
Published: December 2018

As transformações sociais que ocorreram na Europa ao longo do século XIX refletiram- se com particular intensidade no universo alimentar onde, paralelamente à crescente urbanização das cidades, se registou um aumento de serviços de produção e comercialização de preparados culinários bem como no estabelecimento de uma heterógena rede comercial, preparada para responder às necessidades de quase todos os estratos sociais. Lisboa, como capital, não foi estranha a estas alterações, que podem ser percebidas através dos anuários comerciais. Analisados em longo espectro, permitem observar a dinâmica comercial e publicitária da rede comercial de serviços de restauração urbanos, bem como tipologias de estabelecimentos de restauração, serviços e produtos oferecidos e, em determinados casos, preços praticados. A análise aqui conduzida concentra-se num conjunto de sete volumes publicados entre 1871 e 1899 e respeitantes a duas publicações específicas: o Almanach da Agência Primitiva de Annuncios e o Annuario Commercial ou Annuario Official de Portugal.
Controlo, Vigilância e Repressão: A evolução e ação da Guarda Fiscal em Portugal (1885-1945)
Authors: Castro Mariana
Published: December 2018

O estudo da história da Guarda Fiscal tem ficado à margem da historiografia portuguesa, havendo uma atenção acrescida apenas por temas relacionados com outras instituições como a PSP e a PVDE/PIDE. Deste modo, o presente trabalho tem como objetivos principais compreender a dimensão e a representação do termo “ordem pública” e o conceito de polícia; apresentar a orgânica do corpo da Guarda Fiscal, desde a sua criação, organização e distribuição à sua evolução; e, por último, perceber a sua extensão/ação no território português.
Apresentação visual de corpos femininos online: observações sobre a potência textual de selfies e nudes
Authors: Nardelli Thereza , Ziller Joana
Published: December 2018

Se as desigualdades se fazem presentes no acesso e no uso das tecnologias digitais de comunicação, elas parecem ressoar também no âmbito das representações visuais digitais, que deixam ver vidas e corpos femininos nas textualidades online que circulam cotidianamente. Nesse lugar, a fotografia e, especialmente, a prática do autorretrato compartilhado em rede têm papéis importantes na gestão de autovisualidades contemporâneas. Procuramos apresentar o selfie e o nude como formas atuais do autorretrato vernacular, e localizar sua importância e uso na disseminação de visualidades femininas em ambientes online. Concluímos, ao fim do texto, que os aspectos característicos do selfie enquanto gênero fotográfico e midiático, facilitam a apresentação de si, central para a enunciação de visualidades marginais.
Mother(Hood)ing
Authors: Noronha Elizângela Costa de Carvalho
Published: December 2018

Entre as diversas experiências humanas, poucas são alvo de tanta prescrição quanto a maternidade. Não faltam modelos, padrões e regras a serem seguidos por mulheres recém‑chegadas a este universo, ou mesmo pelas mais experientes. Neste artigo, busca‑se discutir a disputa de sentidos entre as noções de maternidade enquanto “natureza feminina” ou como “experiência feminina”. A partir da Análise Crítica Feminista do Discurso (Lazar, 2007) empreendida sobre Edição Especial da Revista Crescer, é possível demonstrar a devida distinção entre as noções de “motherhood” e “mothering” (O’Reilly, 2004).
THE INVESTIGATION OF THE CHEMICAL AND TECHNOLOGICAL PROPERTIES OF BIOMASS WASTE FROM PLANT RAW MATERIALS
Authors: Сартова (Sartova) Кулумкан (Kulumkan) Абдыкеримовна (Abdykerimovna) , Камбарова (Kambarova) Гульнара (Gul'nara) Бексултановна (Beksultanovna) , Байзакова (Baizakova) Гульмира (Gulmira) Лесбековна (Lesbekovna) , Сарымсаков (Sarymsakov) Шайдылда (Shaydylda) , Арапбаева (Arapbaeva) Гульзифа (Gulzifa) Мойдуновна (Moidunovna)
Published: December 2018

The aim of this work is to study the technical, chemical and group composition of biomass of the cotton crop (Cozipiym) and Shyralzhyn (Artemisia Dracunculus), to establish their suitability for obtaining chemical products. The results of the study established that the physical and chemical characteristics of Cotton crop and Shyralzhyn biomass is not inferior to oak wood and can be used for  obtaining valuable chemical products and adsorbents. The study of the group composition of the analyzed plants showed that they can be used later on to produce cellulose, lignin and hemicellulose. The biomass of cotton crop and Shiralzhyn waste contains from 6.64 to 11% of pectin substances, which makes it possible to use as a sorbent against to ions of heavy metals and radionuclides. We isolated vegetable oil (fats) from the seed of tarragon polynyas – Shyralzhyn for the first time, the yield is 15.7%. The development of technology for the complex processing of waste from the cotton crop and Shyralzhyn (wormwood - tarragon) biomass are in prospective. Isolation of triglycerides (oils) from wormwood-tarragon kernels, by transesterification of esters, to produce methyl and ethyl esters of higher carboxylic acids, which can be used as additives to diesel fuels. Establish the main regularities of the recycling process. The extraction of extractive substances, such as tanning, natural dyes, lipids (waxes), antioxidants-polyphenols and pectins.
POLYSACCHARIDES IN TISSUES AMARANTHUS RETROFLEXUS, AGASTACHE RUGOSA AND THLASPI ARVENSE IN THE CONDITIONS OF CENTRAL YAKUTIA
Authors: Слепцов (Sleptsov) Игорь (Igor) Витальевич (Vital'yevich) , Журавская (Zhuravskay) Алла (Alla) Николаевна (Nikolayevna)
Published: December 2018

Isolated fraction of polysaccharides, such as water-soluble polysaccharides, pectins, hemicelluloses A and B from the vegetative mass of plants Amaranthus retroflexus, Agastache rugosa and Thlaspi arvense, grown in the conditions of Central Yakutia. According to the obtained IR spectra it was established that the isolated fractions of polysaccharides from Amaranthus retroflexus, Agastache rugosa and Thlaspi arvense belong to water-soluble polysaccharides, pectins and hemicelluloses. Shows the monosaccharide composition of isolated fractions of polysaccharides from plants grown under conditions of Central Yakutia. The main monomers of the isolated polysaccharides are arabinose (Ara), galactose (Gal), rhamnose (Rha), mannose (Man), xylose (Xyl), glucose (Glc), galacturonic acid (GalA). Revealed the degree of ethrerification of the galacturonic acid in water-soluble polysaccharides and pectins by IR spectra. Shows the differences in the quantitative content and monosaccharide composition of the isolated fractions of polysaccharides, which can be associated with both adaptive rearrangements in the body and with individual plant characteristics.
Avaliação dos requisitos da faixa de pista em aeroportos regionais: uma análise de risco
Authors: Fernandes Helen Feuser , Müller Carlos , Pinto Alves Cláudio Jorge
Published: December 2018

O Brasil é o segundo país com maior número de aeródromos do mundo, atrás apenas dos Estados Unidos. Isso se deve principalmente ao grande número de aeroportos de pequeno porte existentes no país. Devido à dificuldade em se adequar às exigências impostas, esse trabalho tem como objetivo avaliar os requisitos exigidos para a faixa de pista em aeroportos regionais, de modo a viabilizar as operações nesses aeroportos. Para isso foi utilizado um modelo de análise de risco denominado ACRP 50 - Airport Cooperative Research Program, o qual foi aplicado ao Aeroporto de Joinville. Esse modelo foi criado através de uma base histórica de dados operacionais e meteorológicos, e calcula a probabilidade de a aeronave exceder os limites da pista. A partir do modelo, foram discutidas algumas das variáveis que influenciam as operações em aeroportos regionais. Além disso, o nível de segurança da faixa de pista do aeroporto foi avaliado e foram discutidas as implicações de alterações das dimensões da faixa de pista.
Consciousness Energy Healing Treatment: Impact on Physicochemical and Thermal Properties of Silver Sulfadiazine
Authors: Nayak Nayak , Trivedi Mahendra Kumar , Branton Alice , Trivedi Dahryn , Jana Snehasis
Published: December 2018

Silver sulfadiazine is a topical medicine that belongs to sulfa antibiotics class of drugs and used in treating wound infections in burn patients. The aim of this study was to determine the effect of Consciousness Energy Healing Treatment (the Trivedi Effect®) on the various properties of silver sulfadiazine with the help of modern analytical techniques. The sample was divided into two parts; the first part was not given any treatment and considered as a control sample, while the second part was provided the Consciousness Energy Healing Treatment by the Biofield Energy Healer, Gopal Nayak remotely, named as the treated sample. The powder XRD data showed significant alterations in the peak intensities of the treated sample ranging from-30.71% to 47.54% compared to the control sample. The crystallite size was altered ranging from -78.12% to 1.47%; and the average crystallite size was significantly reduced by 31.62% in the treated sample compared to the control sample. The particle sizes were decreased in the treated sample by 12.75%(d10), 4.98%(d50), 0.89%(d90), and 2.92%{D(4,3)}; thus, the specific surface area was significantly increased by 17.31% compared with the control sample. The latent heat of fusion and latent heat of decomposition were profoundly increased by 24.62% and 156.28%, respectively in the treated sample compared to the control sample. The total weight loss was increased by 3.08% and the residue amount was reduced by 4.44% in the treated sample compared to the control sample. Thus, the Trivedi Effect®-Consciousness Energy Healing Treated sample might form a new polymorph of silver sulfadiazine that possesses reduced particle size and improved thermal properties compared to the untreated sample. Therefore, the Biofield Energy treated sample can be used in nutraceutical/pharmaceutical formulation, which would show a better bioavailability and therapeutic response against various infections in comparison to the control sample.
Antiresorptive activity of denosumab in the treatment of osteoporosis in patients with rheumatoid arthritis
Authors: Banshchikova Nadezhda Y. , Letyagina Yelena A. , Omelchenko Vitaliy O. , Korolev Maksim A.
Published: December 2018

Background: fracture risks assessment and determination of bone mineral density are modern methods, generally accepted and widely used. However, they have limitations and disadvantages for the dynamic evaluation of bone remodeling processes in RA-patients with low BMD. The investigation of bone resorption markers is an important issue.
Aims: to compare the antiresorptive activity of denosumab and alendronic acid in patients with rheumatoid arthritis and osteoporosis using β-CTX and osteocalcin (OC).
Materials and methods: forty-two patients were included in the study (16 patients were treated with denosumab, 13 patients – with alendronic acid, 13 patients - control group without any osteoporosis treatment). The quantitative determination of β-CTX and OC as well as dual-energy X-ray absorptionometry (DXA) were carried out for all patients at the first visit with consecutive investigation of bone resorption markers 3 months after. The predictive capacity was determined using the ratio of observed fractures/expected fractures by FRAX.
Results: The level of β-CTX 16% (median 861.6 pg/ml vs. 724.6 pg/ml, p = 0.049) and OC 39% (median 13.9 ng/ml vs 8.5 ng/ml, p = 0.047) decreased significantly in 3 month in RA patients treated with denosumab. The decrease of β-CTX (median 858.9 pg/ml vs. 821.8 pg/ml) and OC (median 14.8 ng/ml vs. 13.9 ng/ml) was observed in the group of patients treated with alendronic acid, but not reached statistical significance.
Conclusions: denosumab had showed better antiresorptive activity compared with bisphosphonates, which was registered 3 month after the start of the treatment.
Hereditary forms of primary hyperparathyroidism
Authors: Mamedova Elizaveta O. , Mokrysheva Natalya G. , Rozhinskaya Liudmila Ya.
Published: December 2018

Primary hyperparathyroidism (PHPT) is sporadic in the majority of cases. Hereditary forms of PHPT are rarer, however, they are of particular interest because they allow a deeper understanding of pathogenesis of parathyroid neoplasia. Hereditary forms of PHPT include multiple endocrine neoplasia type 1 (MEN-1), type 2A (MEN-2A), type 4 (MEN-4), hyperparathyroidism-jaw tumour syndrome (HPT-JT), variants of familial hypocalciuric hypercalcemia (FHH) and familial isolated hyperparathyroidism (FIHP). Mutations in the following genes cause the development of MEN-1, MEN-2A, MEN4, HPT-JT: MEN1, RET, CDKN1B, CDC73, respectively. Variants of FHH are caused by mutations in CASR, AP2S1, GNA11. Gene(s) responsible for the development of the majority of FIHP cases remain unknown.
Identification of hereditary forms of PHPT is important for patients and their first-degree relatives, as it allows defining the necessity of screening to reveal other components of the syndrome, in some cases determines the surgical approach to PHPT, and the risk of development of the disease in offsprings.
This article provides information on hereditary syndromes associated with PHPT and special features of PHPT in each syndrome.
The effectiveness of nutritional vitamin D supplementation and selective vitamin D receptor agonists treatment on secondary hyperparathyroidism in chronic kidney diseases patients
Authors: Egshatyan Lilit V. , Mokrisheva Natalya G.
Published: December 2018

Background: secondary hyperparathyroidism (SHPT) is an early complication of chronic kidney disease (CKD). Maintaining the level of 25(OH)D and parathyroid hormone concentrations in the target range reduce its associated complications (fractures and cardiovascular calcification).
Aims: to examine the effectiveness of vitamin D supplementation and selective vitamin D receptor agonists treatment on SHPT in CKD.
Material and methods: prospective observational study to evaluate the efficacy and safety of vitamin D therapy SHPT in 54 in patients with CKD. The first phase (24 weeks) – treatment of suboptimal 25-hydroxycalciferol (25(OH)D) levels. The second (16 weeks) – treatment colecalciferol-resistant SHPT by combination of cholecalciferol with paricalcitol. Blood samples were taken to assess parathyroid hormone (PTH), 25(OH)D, creatinine, calcium, phosphorus levels and calcium excretion.
Results: After 8 weeks of cholecalciferol treatment all patients achieved 25(OH)D levels above 20 ng/ml, however 78% of patients still had SHPT. After 16 weeks, the decrease of PTH was achieved in all patients, but significantly only in patients with CKD 2 (19.2%, p< 0.01) and 3 (31%, p <0.05), compared with CKD 4 (17%, p >0.05). After 24 weeks of therapy, PTH normalized in all patients with CKD 2, in 15 (79%) with CKD 3 and in 9 (50%) patients with CKD 4. Cholecalciferol treatment resulted in a substantial increase in 25(OH)D levels with minimal or no impact on calcium, phosphorus levels and kidney function.
After 24 weeks we initiated combination therapy (cholecalciferol and paricalcitol) for patients with colecalciferol-resistant SHPT (n=13). PTH levels decreased from 149.1±13.4 to 118.2±14.1 pg/ml at 8 weeks, and to 93.1±9.7 pg/ml (p <0.05) at 16 weeks of treatment. No significant differences in serum calcium, phosphorus or urinary calcium levels. Normalization of PTH was achieved in all patients with CKD 3 and in 8 patients with stage 4. One patient with CKD 4 needed an increase in paricalcitol dose.
Conclusion: Cholecalciferol can be used in correcting vitamin D deficiency in patients with all stages of CKD, however, its effectiveness in reducing PTH in stage 4 is limited. Selective analogs, such as paricalcitol, were well-tolerated and effectively decreased PTH levels.
Functional hypoparathyroidism: causes, pathogenesis, clinical significance in Bone tissue pathology
Authors: Nurullina Guzel M. , Akhmadullina Guzyal I. , Maslova Irina S.
Published: December 2018

Parathyroid hormone (PTH) regulates the maintenance of serum calcium concentration in strict limits through direct effects on bones and kidneys and indirectly due to the effect on the gastrointestinal tract. PTH also regulates phosphorus metabolism. Secondary hyperparathyroidism develops in response to a decreased serum calcium and vitamin D levels, leading to an increased bone resorption. However, the increase in parathyroid hormone above the reference values is not observed in all cases of vitamin D deficiency or hypocalcemia. Supressed or inadequately normal PTH in these conditions is referred to as functional hypoparathyroidism. Various theories have been suggested to explain the functional hypoparathyroidism: magnesium deficiency, intestinal calcistat, lower reference values for plasma PTH compared to current cut off interval, biological variations of vitamin D-binding protein. However, at present none of these theories are generally accepted. The clinical significance of functional hypoparathyroidism may be that vitamin D deficiency, hypocalcemia, and hypomagnesemia are associated with a risk of fracture, regardless PTH level.