bluuebunny/crossref_metadata_2025 huggingface dataset:
La tutoría inclusiva en la Educación a Distancia en etapas postobligatorias no universitarias: ¿un reto o una oportunidad?
Authors: Álvarez Villanueva Cristina
Published: October 2023

La educación a distancia en etapas postobligatorias no universitarias, como el bachillerato, es una solución idónea para atender no solo a aquél alumnado que decide retomar sus estudios ya en la vida adulta, sino para poder dar continuidad a los que por motivos determinados deben permanecer en su domicilio, como es el caso de la convalecencia médica. En el curso 2019/20 se creó por primera vez en la Comunidad Valenciana la atención educativa domiciliaria para la etapa de bachillerato, la cual se realiza con metodología EaD. De este modo, se alinean estos estudios con los nuevos vectores de la inclusión educativa. Y en todo ello, la figura tutorial se erige como la piedra roseta de una educación de calidad a distancia. En este artículo se muestra el trabajo que hemos realizado sobre la tutoría inclusiva en la EaD, analizando los retos y necesidades que debe afrontar todo tutor y mostrando el diseño de las actuaciones y protocolos que se han realizado y que, hoy en día, siguen vigentes y mejorando día a día el trabajo del equipo docente de distancia.
Malaysian Specialists’ Involvement in Research: Attitudes, Barriers and Facilitators
Authors: Bing-Ling Kueh  , Juhanah Gimbo  , Katinah Majunkob  , Fatrina Simon  , Ammar Rafidah Saptu  , Mui-Nyuk Wong
Published: October 2023

In Sabah, the research tradition still needs to be improved due to the need for more participation of specialists in the field of research. Their views and attitudes towards research still need to be improved and expanded. Therefore, this study aimed to assess the willingness of specialists to participate in research and their attitude towards research, as well as the barriers and facilitators in conducting research in government hospitals. This cross-sectional descriptive study was conducted among specialists in three government hospitals in Kota Kinabalu, Sabah using self-administered questionnaires. A total of 49 specialists responded to the questionnaires distributed. Only 44.9% of respondents were involved in research. All the respondents thought that research was advantageous to both patients and society. However, lack of access to expertise, software or statistical analysis and too much red tape in obtaining approvals were among the top barriers to doing research. The main facilitators were to receive acknowledgement of research achievement for their career advancement. In conclusion, most specialists have a positive perception towards research, but more than half of them were not involved in any research during this study.
Controle acionário e estrutura de governança corporativa das empresas brasileiras de capital aberto
Authors: Brandão Isac de Freitas , Silva Laiane de Aguiar , Silva Francisco Valdenuso Almeida
Published: October 2023

Objetivo: Investigou-se a associação entre controle acionário e características da estru­tura de governança corporativa das empresas brasileiras de capital aberto.Método/abordagem: A amostra foi composta por 300 empresas listadas no Brasil, Bolsa, Balcão em 2020. Realizou-se uma análise de correspondência as associações re­levantes entre os tipos de controle acionário e as características da estrutura de gover­nança corporativa.Contribuições teóricas/práticas/sociais: Observou-se associação do tipo de controle acionário com independência do conselho de administração, sobreposição entre con­selho de administração e diretoria executiva, presença de relações familiares e de su­bordinação entre administradores, avaliação e mandato dos administradores, e insta­lação dos órgãos de fiscalização e controle. No campo teórico, estes resultados contri­buem com a discussão sobre os fatores contingenciais que afetam a governança corpo­rativa das empresas.Originalidade/relevância: Os achados do trabalho corroboram como a abordagem contingencial da governança corporativa é influenciada por características do ambi­ente organizacional de cada empresa, dentre as quais o tipo de controle acionário.
ANTIMICROBIAL ACTIVITY OF SELECTED SPICE EXTRACTS ON ESCHERICHIA COLI,SALMONELLA SPP.,AND LISTERIA MONOCYTOGENES
Authors: Jogić Vildana , Džaferović Aida , Toromanović Merima , Nikitović Jelena
Published: October 2023

The study determined antimicrobial activity using the Disc-diffusion method and extracts of three plants: garlic (Allium sativumL.), turmeric (Curcuma longaL.), and parsley (Petroselinum crispumL.) on Escherichia coli, Salmonella ssp. and Listeria monocytogenes. These pathogens have attracted the attention of numerous agencies and researchers,because of the negative impact on food and human health -and because of the impact of disease development on the economy. These studies are necessary and represent potential natural antimicrobial drugs, and due to the resistance of bacteria to known antibiotics, there is a constant increase in global consumer demand for natural ingredients. The tested plant extracts showed excellent antibacterial activity in all three replicates on Escherichia coliwith an average inhibition zone of 21,86 mm and were characterized as ***S -sensitive for the mentioned bacterium. With an average zone of inhibition of 19,052 mm, Curcuma longashowed the strongest effect on the tested bacterium Salmonella enteritidis, which tells us that this bacteria is very sensitive to the extract of the mentioned plant. The study identified zones of inhibition of very low values (˃ 8 mm) in all three tested extracts: Allium sativumL., Curcuma longaL. Petroselinum crispumL., and Listeria monocytogenes.KEYWORDS:Antimicrobial activity, extract, Disc-diffusion method
High-resolution long-term average groundwater recharge in Africa estimated using random forest regression and residual interpolation
Authors: Pazola Anna , Taylor Richard G. , Shamsudduha Mohammad , French Jon , MacDonald Alan M. , Abiye Tamiru , Goni Ibrahim Baba
Published: October 2023

Abstract. Groundwater recharge is a key hydrogeological variable that informs the renewability of groundwater resources. Long-term average (LTA) groundwater recharge provides a measure of replenishment under the prevailing climatic and landuse conditions and is therefore of considerable interest in assessing the sustainability of groundwater withdrawals globally. This study builds on the modelling results of MacDonald et al. (2021) who produced the first LTA groundwater recharge map across Africa using a linear mixed model (LMM) rooted in 134 ground-based studies. Here, continent-wide predictions of groundwater recharge were generated using Random Forest (RF) regression employing five variables (precipitation, potential evapotranspiration, soil moisture, NDVI and aridity index) at a higher spatial resolution (0.1° resolution) to explore whether an improved model might be achieved through machine learning. Through the development of a series of RF models, we confirm that a RF model is able to generate maps of higher spatial variability than LMM; the performance of final RF models in terms of the goodness of fit (R2 = 0.83, 0.88 with residual kriging) is comparable to the LMM (R2 = 0.86). The higher spatial scale of the predictor data (0.1°) in RF models better preserves small-scale variability from predictor data, than the values provided via interpolated LMM; these may provide useful in testing global-to-local scale models. The RF model remains, nevertheless, constrained by its representation of focused recharge and by the limited range of recharge studies in tropical Africa, especially in the areas of high precipitation. This confers substantial uncertainty in model estimates.
Summertime tropospheric ozone source apportionment study in Madrid (Spain)
Authors: de la Paz David , Borge Rafael , de Andrés Juan Manuel , Tovar Luis Miguel , Sarwar Golam , Napelenok Sergey L.
Published: October 2023

Abstract. The design of emission abatement measures to effectivly reduce high ground-level ozone (O3) concentrations in urban areas is very complex. In addition to the strongly non-linear chemistry of this secondary pollutant, precursors can be released by a variety of sources in different regions and locally produced O3 is mixed with that transported from the regional or continental scales. All of these processes depend also on the specific meteorological conditons and topography of the study area. Consequently, high-resolution comprehensive modeling tools are needed to understand the drivers of photochemical pollution and to assess the potential of local strategies to reduce adverse impacts from high tropospheric O3 levels. In this study, we apply the Integrated Source Apportionment Method (ISAM) implemented in the Community Multiscale Air Quality (CMAQv5.3.2) model to investigate the origin of summertime O3 in the Madrid region (Spain). Consistent with previous studies, our results confirm that O3 levels are dominated by non-local contributions, representing around 70 % of mean values across the region. Nonetheless, precursors emitted by local sources, mainly road traffic, play a more important role during O3 peaks, with contributions as high as 25 ppb. The potential impact of local measures is higher under unfavorable meteorological conditions associated with regional accumulation patterns. These findings suggest that this modeling system may be used in the future to simulate the potential outcomes of specific emission abatement measures to prevent high-O3 episodes in the Madrid metropolitan area.
Hydro-PE: gridded datasets of historical and future Penman–Monteith potential evaporation for the United Kingdom
Authors: Robinson Emma L. , Brown Matthew J. , Kay Alison L. , Lane Rosanna A. , Chapman Rhian , Bell Victoria A. , Blyth Eleanor M.
Published: October 2023

Abstract. We present two new potential evaporation datasets for the United Kingdom: a
historical dataset, Hydro-PE HadUK-Grid, which is derived from the HadUK-Grid
gridded observed meteorology (1969–2021), and a future dataset, Hydro-PE UKCP18 RCM, which is
derived from UKCP18 regional climate projections (1980–2080).
Both datasets are suitable for hydrological modelling and provide Penman–Monteith potential evapotranspiration parameterised for short grass, with and without a correction for
interception on days with rainfall. The potential evapotranspiration calculations have been formulated to closely follow the methodology of the existing Meteorological Office Rainfall and Evaporation Calculation System (MORECS) potential evapotranspiration, which has historically been widely used by hydrological modellers in the United Kingdom.
The two datasets have been created using the same methodology to allow seamless modelling from past to future. Hydro-PE HadUK-Grid shows good agreement with MORECS in much of the United Kingdom, although Hydro-PE HadUK-Grid is higher in the mountainous regions of Scotland and Wales. This is due to differences in the underlying meteorology, in particular the wind speed, which are themselves due to the different spatial scales of the data. Hydro-PE HadUK-Grid can be downloaded from https://doi.org/10.5285/9275ab7e-6e93-42bc-8e72-59c98d409deb (Brown et al., 2022)
and Hydro-PE UKCP18 RCM can be
downloaded from
https://doi.org/10.5285/eb5d9dc4-13bb-44c7-9bf8-c5980fcf52a4 (Robinson et al., 2021).
Ocean 2D eddy energy fluxes from small mesoscale processes with SWOT
Authors: Carli Elisa , Morrow Rosemary , Vergara Oscar , Chevrier Robin , Renault Lionel
Published: October 2023

Abstract. We investigate ocean dynamics at different scales in the Agulhas Current system, a region of important interocean exchange of heat and energy. While ocean observations and some of the most advanced climate models capture the larger mesoscale dynamics (> 100 km), the smaller-scale fronts and eddies are underrepresented. The recently launched NASA–CNES Surface Water and Ocean Topography (SWOT) wide-swath altimeter mission observes the smaller ocean geostrophic scales down to 15 km in wavelength globally. Here we will analyse different eddy diagnostics in the Agulhas Current region and quantify the contributions from the larger mesoscales observable today and the smaller scales to be observed with SWOT. Surface geostrophic diagnostics of eddy kinetic energy, strain, and energy cascades are estimated from modelled sea surface height (SSH) fields of the Massachusetts Institute of Technology general circulation model (MITgcm) latitude–longitude polar cap (LLC4320) simulation subsampled at 1/10∘. In this region, the smaller scales (<150 km) have a strong signature on the horizontal geostrophic strain rate and for all eddy diagnostics in the Western Boundary Current and along the meandering Agulhas Extension. We investigate the horizontal cascade of energy using a coarse-graining technique, and we observe that the wavelength range where the inverse cascade occurs is biased towards larger mesoscale wavelengths with today’s altimetric sampling. We also calculate the projected sampling of the eddy diagnostics under the SWOT swaths built with the NASA–CNES simulator to include the satellite position and realistic noise. For the swaths, a neural network noise mitigation method is implemented to reduce the residual SWOT random error before calculating eddy diagnostics. In terms of SSH, observable wavelengths of 15 to 20 km are retrieved after neural network noise mitigation, as opposed to wavelengths larger than 40 km before the noise reduction.
دور نظام الرقابة الداخلية في تحقيق الشفافية الإدارية (دراسة ميدانية على موظفي الأحوال المدنية في محافظة جدة)
Authors:   عضو هيئة تدريس جامعة الملك عبدالعزيز، المملكة العربية السعودية, العمري ثنوى , الحربي شروق ,   ماجستير الإدارة العامة، كلية الاقتصاد والإدارة، جامعة الملك عبدالعزيز، المملكة العربية السعودية
Published: October 2023

هدفت هذه الدراسة إلى توضيح مستوى تطبيق نظام الرقابة الداخلية بأبعادها المتمثلة بيئة الرقابة، تقدير المخاطر، أنشطة الرقابة، المعلومات والاتصالات، والمتابعة في نظام الأحوال المدنية بمحافظة جدة، والتحقق من نجاح ذلك في تحقيق الشفافية الإدارية، كما هدفت في الكشف عن الفروق ذات الدلالة الإحصائية في استجابات أفراد العينة بين نظام الرقابة الداخلية بأبعادها والشفافية الإدارية والتي تعزى للمتغيرات الديموغرافية. وقد اعتمدت الدراسة على المنهج الوصفي التحليلي، واستخدمت الاستبانة كأدوات لجمع البيانات، وتم عمل حصر شامل لمجتمع الدراسة والبالغ عددهم 600 موظفاً، ثم تمت المعالجة الإحصائية للبيانات وتوصلت الدراسة للعديد من النتائج وأهمها: أن الأحوال المدنية بمحافظة جدة قد التزمت بلائحة وحدات المراجعة الداخلية الموحدة في الأجهزة الحكومية والمؤسسات العامة الصادرة بقرار مجلس الوزراء رقم 129 في تاريخ 6/4/1428 هـ، مما أدى ذلك إلى تحقيق الشفافية الإدارية المطلوبة الناتجة عن دور نظام الرقابة الداخلية فيها، وأن مستوى نظام الرقابة الداخلية والشفافية الإدارية كان مرتفعاً دون تمييز، ولا توجد فروق ذات دلالة إحصائية في استجابات الأفراد بين نظام الرقابة الداخلية بأبعادها والشفافية الإدارية تعزى للمتغيرات الديموغرافية. وكانت أبرز توصيات الدراسة: إعداد برنامج يختص بنظام الرقابة الداخلية للمؤسسات الحكومية، العمل على استحداث وحدة خاصة بإدارة المخاطر داخل المؤسسات الحكومية، بناء خطة واضحة لنظام الرقابة الداخلية لتعزيز مبدأ الشفافية لمؤسسة الأحوال المدنية بمحافظة جدة.
The Evolution of Urban Physical Education Development Model and Its Innovative Development Strategy
Authors: Wang Zi , Zhao Min
Published: October 2023

In China's urban environment, physical education has changed significantly during the last few decades. Physical education programs are in higher demand than ever, especially in colleges, as people's knowledge of health and fitness has grown. This study examines the effectiveness of an innovative physical education development and strategy, based on self-determination theory principles, in promoting physical activity and motivation among undergraduate students in Taiyuan, China. A total of 256 participants enrolled in fitness-based physical activity classes at a university in China were included in the study. Data was collected through self-reported measures of physical education, physical fitness, innovativeness, lifestyle behavior, and academic achievement. Statistical analyses were conducted using SPSS software. The findings suggest that the physical education development model and strategy may be effective in promoting physical education, physical fitness, innovativeness, and academic achievement among undergraduate students in China. Further research may be needed to explore the relationship between academic achievement and lifestyle behavior in more detail and to identify any other factors that may be influencing academic achievement.
USE OF VORTEX LAYER APPARATUS FOR PREPARATION OF OILED SCALE AND ZINC-CONTAINING DUST AND SLUDGE FOR BRIQUETTING
Authors: Бижанов А.М.
Published: October 2023

Впервые показана эффективность использования аппаратов вихревого слоя (АВС) для обезмасливания окалины и обесцинкования шламов до состояния, позволяющего применять их в качестве компонентов брикетов без вреда для здоровья и угрозы целостности футеровки доменных печей. Воздействие ряда интенсивных физико-механических процессов в рабочем пространстве АВС, инициированных вращающимся магнитным полем, приводит к измельчению частиц обрабатываемого материала, к изменению его структуры и свойств. Обработка замасленной окалины в АВС позволяет очистить окалину от масла (до 0,01%) с сохранением масла в качестве продукта. АВС позволяет сокращать продолжительность процесса выщелачивания цинка до 30 мин; селективно извлекать оксид железа и оксид цинка до конечного содержания в нерегенерируемом осадке до 0,09 и 0,043% по массе, соответственно. Изучен вещественный состав образцов замасленной и переработанной во вращающемся магнитном поле окалины. Показана возможность использования АВС для активации связующих для брикетирования. Предложены схемы промышленной реализации технологий обезмасливания и обесцинкования материалов в АВС.

For the first time, the effectiveness of the use of vortex layer apparatuses (VLA) for deoiling of mill scale and dezincification of sludge to a state that allows them to be used as components of briquettes without harm to health and threat to the integrity of the lining of blast furnaces is shown. The impact of a number of intense physical and mechanical processes in the VLA working space, initiated by a rotating magnetic field, leads to the grinding of particles of the processed material, to a change in its structure and properties. The treatment of oily mill scale in VLA makes it possible to remove oil from the scale (up to 0.01%) while retaining the oil as a product. A VLA allows you to reduce the duration of the zinc leaching process to 30 minutes; selectively recover iron oxide and zinc oxide to a final content in the non-recoverable sludge of up to 0.09% and 0.043% by weight, respectively. The material composition of samples of oily mill scale and processed in a rotating magnetic field has been studied. The possibility of using VLA to activate binders for briquetting is shown. Schemes for the industrial implementation of technologies for deoiling and dezincification of materials in VLA are proposed.
The impact of imuheptin and imupurin on cytokine profile and antioxidant status in rat model of inflammation
Authors: Gutu Ina , Bacinschi Nicolae , Gudumac Valentin
Published: October 2023

Introduction. Insects, throughout evolution, have developed a huge arsenal of active compounds, which they use to defend themselves against enemies and diseases, at the same time in recent years insects have shown great interest as a source of food rich in biologically active substances. Research in recent decades has shown that insects produce a variety of proteins and peptides with antibacterial, antifungal, antiviral, immunomodulatory, anti-inflammatory, antioxidant, antitumor, hepatoprotective, antithrombotic, antihypertensive and detoxifying activity during or after contact with the microbial agent or unfavourable factor. Material and methods. The anti-inflammatory effect of imuheptin and imupurin was investigated in a rat model of subacute inflammation induced by subcutaneous implantation of felt discs. The intensity of the exudative and proliferative phase of inflammation, cytokine profile (TNFalpha, IL-6, IL-10), ceruloplasmin and antioxidant enzymes (superoxide dismutase, catalase, glutathione reductase, glutathione peroxidase and glutathione-S-transferase) in the serum of rats were evaluated. Results. Imuheptin and imupurin reduced the level of pro-inflammatory cytokines (TNF-alpha, IL-6) and increased that of the anti-inflammatory cytokine (IL-10), as well as ceruloplasmin, glutathione reductase and glutathione peroxidase in subacute inflammation. Additionally, imupurin significantly increased the level of catalase and imuheptin that of glutathioneS-transferase. Conclusions. Imuheptin and imupurin determined a moderate effect of inhibiting the exudative and proliferative processes, compared to the reference preparation - dexamethasone, but with a favourable effect on the cytokine profile, decreasing the level of pro-inflammatory cytokines (TNF-alpha, IL-6) and increasing the level the anti-inflammatory one (IL-10), as well as the modulation of antioxidant enzyme activity.
Current affairs in the use of medical ozone. Biological effects. Mechanisms of action
Authors: Cernei Natalia , Sandru Serghei , Cobilețchi Serghei , Grabovschi Ion , Civirjic Ivan , Baltaga Ruslan
Published: October 2023

Introduction. Oxygen-ozone therapy stands as a medically endorsed practice confirmed by numerous international clinical studies. Various authors have illustrated the beneficial clinical outcomes of ozone therapy in terms of its capacity to regulate redox balance, cellular inflammatory responses, and adaptation to ischemia/reperfusion processes. Ozone therapy extends to encompass a range of viral infections, inflammatory disorders, and degenerative ailments, used as both monotherapy and as an adjunct to unified conventional therapies. Material and methods. Narrative literature review study. Bibliographic search was conducted using the PubMed, Hinari, and SpringerLink databases, as well as the National Center of Biotechnology Information and Medline. Articles published between 1990 and 2022 were selected using various combinations of keywords, including “ozone”, “ozone therapy”, “mechanisms of ozone action”, “biological effects of ozone”, “antioxidant effect”, “anti-inflammatory effect” and “immunomodulatory effect.” Information regarding ozone’s mechanisms of action was identified and processed. Following the database information processing and search criteria, a total of 475 full-text articles were found. The final bibliography consists of 52 relevant sources that were deemed representative of the materials published on the topic of this synthesis article. Results. The effects of ozone on oxygen metabolism are explained by changes in the rheological properties of blood, including inhibition of erythrocyte aggregation and stimulation of 2,3-diphosphoglycerate in erythrocytes, favoring the transport and delivery of oxygen to tissues while facilitating the substantial elimination of nitric oxide and increasing blood flow. Intracellular triatomic oxygen enhances the oxidative carboxylation of pyruvate, stimulating ATP production, which also contributes to reducing peripheral vascular resistance. Conclusions. Ozone generates a moderate oxidative stress. Yet, it can set off several beneficial biochemical mechanisms that reactivate both the intra- and extracellular antioxidant systems and reverse chronic oxidative stress in various inflammatory and degenerative processes. Ozone induces a mild activation of the immune system by triggering neutrophil activation and stimulating the synthesis of certain cytokines (IL-2, TNF-α, IL-6, and IFN-γ), thereby initiating a complete cascade of immune responses. Ozone therapy yields the following biological reactions: optimization of blood circulation and oxygen delivery to ischemic tissue, regulation of cellular antioxidant enzymes, initiation of a slight immune system activation, and enhancing the release of growth factors.
Optimization of pyridine based Schiff bases: Design, synthesis and determination of anti-inflammatory, antioxidant and antimicrobial activity
Authors: Kale Vinod , Bhopalkar Gangadhar
Published: October 2023

The present paper proposed the tri-potassium phosphate catalyzed synthesis of some novel series of Schiff bases (3a to 3l) derived from 2-aminopyridine using microwave technique. All synthesized Schiff bases were confirmed by different spectroscopic methods. Further all synthesized imines have been evaluated to screen for antimicrobial, antioxidant and anti-inflammatory activity. The compound 3c displays potent anti-inflammatory activity with 42.307%±1.322 inhibition of inflammation. The antioxidant activity data revealed that all synthesized Schiff bases exhibit potency to scavenge DPPH and nitric oxide radicals. Antimicrobial properties of these compounds showed moderate to excellent growth of inhibitory activity against various tested pathogens. Our observations and examination for pharmacological study towards the presence of active pharmacological functional groups present in the main structural nucleus of synthesized imines. Therefore, present study may lead to the development of a new class of anti-inflammatory and antioxidant drugs with structural modification.
Academic Stress and Self Esteem among Nursing Students
Authors: R. Uma.
Published: October 2023

Background: Nursing is one of the long and quite stressful courses of UG study programme. Stress and self-esteem are common issues that everyone has to cope with at some time in their lives and they could also affect other things going on in a persons’ life. Objectives: The study aims to assess and compare the academic stress and self-esteem among 1st and 2nd year nursing students and associate with selected demographic variables. Methodology: A descriptive cross sectional research design was adopted. A total of 67 nursing students were selected by using non probability purposive sampling technique in a selected nursing college. Through the self-administered method, standardized Academic stress scale and Rosenberg self-esteem scale were used to collect data from the selected samples and analysed using descriptive and inferential statistics. Results: Among the 35 samples of the B.Sc(N) 1st year students 37% had moderate stress, 29% had high stress and 80% had moderate self esteem. Among the 32 samples of B.Sc(N) 2nd year students, 34% of the samples had moderate and high level of stress respectively and 94% had moderate self esteem. There was a significant association between academic stress with selected demographic variables such as age, year of study, birth order, type of family and family support. There was a significant association in the level of self esteem with selected demographic variables such as age, birth order and parental status. Conclusion: Hence, the study findings recommends there need to be a some relaxation programme like yoga, meditation could be suggested regularly for nursing students to overcome their various stresses.
Effectiveness of Pamphlet on Knowledge regarding Planned Parenthood among First Time would be parent in selected area
Authors: Subhash Ghadage Snehal , S. Gaikwad Vanita , Tomy Sara , Naik Pournima
Published: October 2023

Introduction: The present study was aimed to assess the “Effectiveness of pamphlet on knowledge regarding Planned Parenthood among first time would be parent in selected area.” Objectives: In view of the nature of the problem under study and to accomplish the objectives of the study, evaluative approach was found to be appropriate to describe the knowledge on Planned Parenthood among first time would be parent. In this study, study design was used quasi experimental, one group pre-test and post-test. The study was conducted at selected area. Material and Method: In the present study, quasi experimental one group pre-test, post-test research design was used. Total 60 eligible couple sample were selected by Non probability purposive sampling technique as per the inclusion criteria. Structured Knowledge Question was used in this study. Findings: The comparisons of the pretest and post-test means of the knowledge regarding Planned Parenthood among first time would be parent in selected area were done by the paired ‘t’ test. The test was conducted at 5% level of significance. The pretest average score was 7.93 with standard deviation of 1.33. The posttest average score was 12.60 with standard deviation of 1.11. The test statistics value of the paired t test was 22.14 with p value 0.00. The chi square test was used to see the association between pre-test knowledge scores regarding Planned Parenthood among first time would be parent in selected area with selected demographic variable of eligible couples. Conclusion: The study concludes that the pamphlet was effective improving the knowledge of eligible couple regarding Planned Parenthood among first time would be parent.
A Study to Assess the Knowledge and Attitude Regarding Diabetes Mellitus among Diabetic and Non Diabetic Patients attending Medicine Outpatient Department
Authors: Sony Nishu , Pal Kaur Jasinder , Singh Choudhary Virendra
Published: October 2023

The study was to assess the knowledge and attitude regarding Diabetes Mellitus among diabetic and non diabetic patients, and compare the knowledge and attitude regarding Diabetes Mellitus among diabetic and non diabetic patients. A Comparative Descriptive research design was used Sample size of 100 diabetic and non diabetic patients (50 in diabetic mellitus and 50 in non diabetic mellitus) were selected through non probability convenient sampling technique. The study was conducted in GGSMCH hospital Faridkot, Punjab. Results: Data was collected through the self structured knowledge questionnaire and attitude scale. Discussion was based on statistical analysis in diabetic majority of diabetic study subjects 43(86%) had average knowledge followed by 4(8%) had poor knowledge and only 3(6%) had good knowledge. In non diabetic patients majority 25(50%) had average knowledge followed by 18(36%) had poor knowledge and only 7(14%) had good knowledge. 42(84%) had fair attitude whereas in diabetic study subjects and in non diabetic study subjects figure presents the 40(80%) poor attitude. The coefficient of correlation between knowledge and attitude regarding diabetes mellitus among diabetic patients is 0.22 and coefficient of correlation between knowledge and attitude regarding diabetes mellitus among non diabetic patients is 0.25.
Relief of discomfort and inflammation through surgical extraction of an impacted tooth: A case report
Authors:   Aviation General Hospital of China Medical University and Beijing Institute of Translational Medicine, Zhao Qiang
Published: October 2023

A 28-year-old female patient presented to our dental department with a complaint of discomfort and pain in the back of her mouth on the left side.
Severe post-COVID virus positive lymphocytic myocarditis with infective endocarditis: Сhallenges of diagnosis and treatment
Authors:   The First Sechenov Moscow State Medical University under Ministry of Health of the Russian Federation, 8-2, Trubetskaya street, Moscow, OV Blagova
Published: October 2023

A 39-year-old patient with bicuspid aortic valve underwent COVID-19 in August 2020. In September, he developed fever, dyspnea, arthralgias, hemorrhagic rash, followed by biventricular heart failure (December 2020).
A benign radiological spleen for a rare malignant splenic angiosarcoma
Authors:   Sengkang General Hospital, Singapore, Deanna Lee Wai Ching
Published: October 2023

We discuss a case of a 69-year-old female presenting with unintentional loss of weight. Computer tomography of the abdomen revealed mottled liver appearance and cystic liver
Treatment of lorlatinib induced hypercholesterolemia with PCSK9 inhibitors; A new solution to an emerging need in non-small cell lung cancer therapy
Authors:   University of Otago, Dunedin, New Zealand, C Ashton John
Published: October 2023

Lorlatinib is a third generation ALK inhibitor used in the treatment of non-small cell lung cancer. Lorlatinib invariably causes hypercholesteremia, though most patients respond to statin therapy.
Spread Through Air Spaces (STAS): Where is it in the management of lung cancer?
Authors:   The First Affiliated Hospital of Zhejiang University School of Medicine, 79 Qingchun Road, Hangzhou, Zhejiang, China, Li Hequan
Published: October 2023

First identified in 1980 and formally defined by the WHO in 2015, Spread Through Air Spaces (STAS) has attracted much attention in recent years
Lung cancer metastasis to the breast: Consideration of an unusual presentation
Authors:   Director, Clinical Research, Department of Pathology, Greenville SC, USA, Schammel Christine
Published: October 2023

Background: The EML4-ALK fusion oncogene is found in 2 to 7% of all non-small cell lung cancers, most of which are adenocarcinomas. ALK positive lung malignancies are rare; even more rare are primary ALK positive lung malignancies that metastasize to the breast.
Thyroid-like intrahepatic cholangiocarcinoma: An easily misdiagnosed case and molecular features analysis
Authors:   Huazhong University of Science and Technology, Guo Fang
Published: October 2023

Thyroid-like intrahepatic cholangiocarcinoma is a rare and easily misdiagnosed malignant neoplasm. Five cases in surgical specimen have been reported in the English literature while lack comprehensive gene mutations analysis.
Tissue Thermal Response in Photobiomodulation Therapy: A Theoretical Study
Authors:   Amirkabir University of Technology, P.O. Box 15875-4413, Tehran, Iran, Parvin Parviz
Published: October 2023

The PBM treatment method is widely used in the treatment of oral and dental diseases, especially the fast treatment of aphthous.
Multivariate Dependence beyond Correlation: Nonparametric Copulas
Authors: Ghosh Sujit
Published: October 2023

In the field of climate, finance, insurance, and system reliability, etc., it is often of interest to measure the dependence among variables by modeling a multivariate distribution using a copula. The copula models with parametric assumptions are easy to estimate but can be highly biased when such assumptions are false, while the empirical copulas are non-smooth and often not genuine copula, making the inference about dependence challenging in practice. As a compromise, the empirical Bernstein copula provides a smooth estimator, but the estimation of tuning parameters remains elusive. In this paper, by using the so-called empirical checkerboard copula, we build a hierarchical empirical Bayes model that enables the estimation of a smooth copula function for arbitrary dimensions. The proposed estimator based on the multivariate Bernstein polynomials is itself a genuine copula, and the selection of its dimension-varying degrees is data-dependent. We also show that the proposed copula estimator provides a more accurate estimate of several multivariate dependence measures, which can be obtained in closed form. We investigate the asymptotic and finite-sample performance of the proposed estimator and compare it with some nonparametric estimators through simulation studies. An application to portfolio risk management is presented, along with a quantification of estimation uncertainty.
Catching the Culprit: How Chorea May Signal an Inborn Error of Metabolism
Authors: Ortigoza-Escobar Juan Darío
Published: October 2023

Background: Movement disorders, particularly chorea, are uncommon in inborn errors of metabolism, but their identification is essential for improved clinical outcomes. In this context, comprehensive descriptions of movement disorders are limited and primarily derived from single cases or small patient series, highlighting the need for increased awareness and additional research in this field. Methods: A systematic review was conducted using the MEDLINE database and GeneReviews. The search included studies on inborn errors of metabolism associated with chorea, athetosis, or ballismus. The review adhered to PRISMA guidelines. Results: The systematic review analyzed 76 studies out of 2350 records, encompassing the period from 1964 to 2022. Chorea was observed in 90.1% of the 173 patients, followed by athetosis in 5.7%. Various inborn errors of metabolism showed an association with chorea, with trace elements and metals being the most frequent. Cognitive and developmental abnormalities were common in the cohort. Frequent neurological features included seizures, dysarthria, and optic atrophy, whereas non-neurological features included, among others, facial dysmorphia and failure to thrive. Neuroimaging and biochemical testing played crucial roles in aiding diagnosis, revealing abnormal findings in 34.1% and 47.9% of patients, respectively. However, symptomatic treatment efficacy for movement disorders was limited. Discussion: This study emphasizes the complexities of chorea in inborn errors of metabolism. A systematic approach with red flags, biochemical testing, and neuroimaging is required for diagnosis. Collaboration between neurologists, geneticists, and metabolic specialists is crucial for improving early detection and individualized treatment. Utilizing genetic testing technologies and potential therapeutic avenues can aid in the improvement of patient outcomes.
Glenohumeral versus subacromial steroid injections for impingement syndrome with mild stiffness: a randomized controlled trial
Authors: Kim Yong-Tae , Kim Tae-Yeong , Lee Jun-Beom , Hwang Jung-Taek
Published: October 2023

Background: The subacromial (SA) space is a commonly used injection site for treatment of impingement syndrome. For shoulder stiffness, glenohumeral (GH) injections are commonly performed. However, in cases of impingement syndrome with mild shoulder stiffness, the optimal site of steroid injection has yet to be identified.Methods: This prospective, randomized study compared the short-term outcomes of ultrasound-guided GH and SA steroid injections in patients who were diagnosed with impingement syndrome and mild stiffness. Each group comprised 24 patients who received either a GH or SA injection of 40 mg of triamcinolone. Range of motion and clinical scores were assessed before and 3, 7, and 13 weeks after the injection.Results: GH and SA injections significantly improved the range of motion and clinical scores after 13 weeks of follow-up. Notably, targeting the GH joint resulted in an earlier gain of forward elevation, external rotation, and internal rotation in 3 weeks (P<0.001, P=0.012, and P=0.002, respectively) and of internal rotation and a Constant-Murley score in 7 weeks (P<0.001 and P=0.046). Subsequent measurements were similar between the groups and showed a steady improvement in all ranges of motion and clinical scores.Conclusions: GH injections may be more favorable than SA injections for treatment of impingement syndrome with mild stiffness, especially in improving the range of motion in the early period. However, the procedures showed similar outcomes after 3 months.Level of evidence: I.
Breast Cancer Detection using Image Segmentation
Authors:   Amity School of Engineering & Technology, Amity University Uttar Pradesh, India, Sethi Mohit
Published: October 2023

Breast cancer is the most prevalent kind of malignancy in women, and diagnostic systems that apply artificial intelligence algorithms for breast imaging have shown positive results. Two methods that increase the precision of detecting breast tu-mors from mammography images are a multiclass support vector machine model and a deep convolutional neural network (DCNN) using K-means clustering. To accurately diagnose breast tumors, the pectoral muscle (PM) border must still be dis-tinguished from the rest of the breast tissue. By merging the transfer learning model with a number of pre-trained CNN structures, this research offers an Ensemble-Net model for distinguishing the PM boundary from the rest breast region in mammograms. The segmentation procedure consists of 2 steps. According to the input, various regions of interest are formed in the initial phase and include the object.
Helping Finance Students Think About the Shareholder Value Maximization Objective
Authors: Jones Steven
Published: October 2023

One of the most contentious debates in the field of financial management involves the relative merits of a “shareholder”versus a “stakeholder” focus. While there are often-overlooked common elements in the “shareholder” and “stakeholder”arguments, clearly there are sharp differences between the two as well. Business school professors have the often-difficult taskof describing these differences for their students. This paper describes possible approaches to this issue, both at a surface levelfor an introductory finance course, and in a more applied manner for an advanced course.

The author proposes an approach of enlightened self-interest, in which corporate management observes its fiduciaryresponsibility to shareholders by pursuing long-term shareholder value maximization, and at the same time realizes that thispursuit is likely to be fruitless if other constituencies are neglected. However, it is hoped that the teaching suggestions offered inthis paper will be helpful, both to those who agree with this approach, and to those who hold a different view.
Teaching Monte Carlo Simulation Using a Multi-Sheet Excel Workbook
Authors: Duan Xiaoman , Stretcher Robert
Published: October 2023

One of the challenges in finance education is to get across the importance of taking risk into consideration when making capital investment decisions. Once risk information is collected, it is up to the decision maker how to use it, which brings in differing approaches from manager to manager. The availability of risk indicators, however, is a valuable element in the decision process.

One strategy that seems to provide robust input for these decisions is the use of simulation to illustrate the variability of critical values, such as a net present value. A simulation may capture several key input variables’ deviations. Typical inputs exhibiting uncertainty are sales growth, fixed and variable costs, and tax rates. Some argue that the cost of capital is variable as well, although these are determined nominally at the time of financing, usually at the outset of a project, and thus may not be as needy of simulation. This article demonstrates a teaching technique for using a simulation case.
Are Increasing Interest Rates From Leverage Consistent with Modigliani-Miller Arbitrage?
Authors: Pettengill Glenn , Lander Diane
Published: October 2023

Among the most important contributions to the finance literature is Modigliani and Miller’s seminal work on capitalstructure. As still taught in virtually all corporate finance textbooks, their famous Propositions I and II provide the foundation for the analysis of capital structure. Proposition I argues that under certain assumptions capital structure is irrelevant to the value of the firm. Proposition II describes the change in the required return to equity in response to a change in financial risk due to a change in leverage. In establishing Proposition II, Modigliani and Miller rely critically on an arbitrage process that forces the cost of equity to assume a value consistent with Proposition I. Although most of their analysis assumes constant debt rates, Modigliani and Miller allow that interest rates do vary with the level of leverage but that this variation does not affect the arbitrage process. In this paper, we argue that the arbitrage process is no longer dependable when debt rates change due to variation in leverage and discuss implications for teaching capital structure.
Stock Simulations: Game and Group Design to Reduce Risky Behavior and Enhance Learning
Authors: Lottridge Anderson Nancy
Published: October 2023

Stock simulations have been used at all levels of education to teach about the investment process. For college classes, a 15 week semester means the game will be limited to around 12 weeks. The short-term nature of the game may encourage risky behavior, but the educational component of the simulation may be worth the exposure to risk-taking in order to enhance learning through a hands-on experience. I design a simulation and construct various types of student groups. Through observations and a student questionnaire, I determine that simulation complements a traditional lecture. I also find that the design of the game and the design of student groups may reduce risky behavior and enhance learning.
Empirical Finance in R: An Introduction
Authors: Sabbaghi Omid
Published: October 2023

This article provides an introduction to the R statistical programming language with teaching applications in finance. R is a statistical software environment for data analysis and graphics. Specific applications presented in this study include the calculation of descriptive statistics for financial returns of 2 stocks and the S&P 500 Index. The R language is useful in today’s finance classrooms because of its open-source coding environment, ease of learning, and high number of financial data analysis packages contributed by users worldwide.
Study of the effect developed chisel plow on some energy requirements and some soil properties in a clayey mixture soil
Authors: Mohammed Luay-lazim , Al-Faris Murtada Abd Al-Azeem Abd Al-Nabi
Published: October 2023

The experiment was conducted at the fields of the College of Agriculture - University of Basra to study the effect height of sweeps shank equipped with the developed chisel plow (10 and 20 cm), with three depths (15, 25 and 35 cm) and three lateral distance (20, 25 and 30 m), on the field performance indicators of the draft force and the area of loosened soil. In a mixed alluvial soil with a density of (1.25) g-cm3 and a moisture content of (15.17) %, the experiment was designed according to the randomized complete block design (RCBD).

     The drafting force increased when the lateral distance and plowing depths increased, while it decreased when the arms of the sweeps shank increased by 20 cm. The loosened area increased when the plowing depths and the lateral distance increased when the arms of the duck hind legs were 10 cm high. The highest drafting force recorded at the height of the arms of the sweeps shank20 cm, the distance between them 30 cm, and the plowing depth 35 cm. The highest loosened area recorded at the height of the arms of the sweeps shank10 cm and the depth of plowing 35 cm.
Köse, Ensar. Ağalar: Konya Aladağ’da Âyan Bir Türkmen Ailesinin Tarihi (1680-1880). İstanbul: Vakıfbank Kültür Yayınları, 2023. 322 Sayfa. ISBN: 9786256385573
Authors: GÜLDÖŞÜREN Arzu
Published: October 2023

Bu yazı, Ensar Köse’nin 2023 yılında yayınlanan ve Konyalı bir âyan ailesinin tarihini incelediği Ağalar: Konya Aladağ’da Âyan Bir Türkmen Ailesinin Tarihi (1680-1880) adlı çalışmasını ele almaktadır. Yazıda, kitabın bölümlerinden bahsedildikten sonra araştırmanın yöntemi ve kaynakları üzerinde durulacak, çalışmanın literatüre katkısı değerlendirilecektir. Çalışma, ailenin tarihi üzerinden âyanların taşradaki faaliyetlerinden kesitler aktarmakta, Aladağ’ın tarihine ve bölge insanının sosyo-ekonomik durumuna dair sunduğu bilgilerle literatüre katkı sağlamaktadır.
Le rôle des figures féminines dans les tournois et pas d’armes à la cour de Bourgogne
Authors: Jeay Madeleine
Published: October 2023

Sous l’influence de l’imaginaire arthurien, on observe une transformation du caractère des tournois qui, en devenant des spectacles chevaleresques, accordent une place aux femmes pendant l’épreuve, pour la remise des prix et lors des réjouissances qui suivent. Leur rôle dépend de la dimension littéraire des textes et est plus développé dans les biographies chevaleresques que chez les chroniqueurs. Il dépend aussi du contexte de la joute : dans les pas d’armes, elles interviennent aussi comme protagonistes des scénarios mis en scène.