bluuebunny/crossref_metadata_2025 huggingface dataset:
Thực trạng dinh dưỡng và một số yếu tố liên quan tới học sinh trừong Trung học cơ sở Lê Lợi, Hải Phòng năm 2019 - 2020
Authors: Đức Nguyễn Quang , Hương Dương Thị , Quyến Phạm Huy
Published: April 2021

Nghiên cứu mô tả cắt ngang trên 1837 học sinh trường trung học cơ sở Lê Lợi, quận Lê Chân, thành phố Hải Phòng từ tháng 10 năm 2019 đến tháng 3 năm 2020 nhằm mô tả tình trạng dinh dưỡng và một số yếu tố liên quan trên đối tượng nghiên cứu này. Kết quả, tỷ lệ học sinh thừa cân béo phì là 29,9%, tỷ lệ thừa cân béo phì ở học sinh nam cao hơn học sinh nữ (37,3% và 22,2%). Bên cạnh đó, tỷ lệ học sinh thiếu dinh dưỡng chung là 4,8%. Một số yếu tố liên quan đến tình trạng thừa cân béo phì của học sinh là: Giới tính nam; ăn 4 bữa chính trở lên trong ngày; có thói quen ăn đêm; ăn thức ăn ngọt ≥ 1 lần / ngày; uống nước ngọt có ga. Một số yếu tố liên quan đến tình trạng thiếu dinh dưỡng của học sinh là: Bỏ bữa; không ăn sáng môi ngày. Từ kết quả này, nghiên cứu góp phần đưa ra các can thiệp dinh dưỡng phù hợp cho lứa tuổi này trên địa bàn thành phố Hải Phòng.
Đăc điêm lâm sàng, cận lâm sàng và kết quả điều trị ngoại trú bệnh nhân đái tháo đường týp 2 tại Viện Y học biển năm 2017
Authors: Tâm Nguyễn Văn , Đức Vũ Việt , Quyến Phạm Huy
Published: April 2021

Nghiên cứu này nhằm mục tiêu mô tả đặc điểm lâm sàng, cận lâm sàng và kết quả điều trị ngoại trú bệnh nhân đái tháo đường (ĐTĐ) týp 2 tại Viện Y học biển năm 2017. Nghiên cứu mô tả cắt ngang thông qua khám lâm sàng, xét nghiệm máu và theo dõi quá trình điều trị 62 bệnh nhân được chẩn đoán đái tháo đường týp 2 điều trị ngoại trú tại Viện Y học biển. Kết quả nghiên cứu thu được tỷ lệ bệnh nhân ĐTĐ có triệu chứng mệt mỏi là (48,4%), uống nhiều (45,2%), đái nhiều (38,7%), gầy sút cân (29,0%); tỷ lệ bệnh nhân ĐTĐ có tăng huyết áp là (51,6%), bệnh mạch vành (22,6%), tổn thương đáy mắt (12,9%), tê bì dị cảm chi dưới (12,9%), tổn thương thận (6,5%); Nồng độ đường huyết và HbA1C của bệnh nhân bị bệnh ĐTĐ là 8,93 ± 2,19 mmol/l và 7,56 ± 1,36%. Mức độ kiểm soát đường huyết loại tốt và trung bình tăng sau 3 tháng và 6 tháng điều trị. Mức độ kiểm soát HbA1C ở bệnh nhân ĐTĐ loại tốt tăng sau 3 tháng và 6 tháng điều trị.
Thực trạng sử dụng và bảo quản hóa chất bảo vệ thực vật của người dân tại 2 xã, thị xã Quảng Yên, Quảng Ninh năm 2019
Authors: Thành Nguyễn Văn , Thắm Nguyễn Thị , Dung Trần Lê , Hải Phạm Thanh , Chính Nguyễn Quang , Đức Cáp Minh
Published: April 2021

Nghiên cứu cắt ngang tiến hành trên 400 hộ gia đình nhằm mô tả thực trạng sử dụng và bảo quản hóa chất bảo vệ thực vật của người dân tại 2 xã, thị xã Quảng Yên, Quảng Ninh, từ tháng 1 năm 2019 đến tháng 6 năm 2019. Kết quả nghiên cứu cho thấy 25,2% người dân pha thuốc không theo đúng chỉ dẫn trên bao bì, 91,5% người dân sử dụng ít nhất 1 loại bảo hộ lao động khi phun thuốc, tuy nhiên vẫn còn 8,5% người dân không sử dụng bất kì 1 loại bảo hộ lao động nào. Trên 90% người dân đi phun thuốc vào sáng sớm/ chiều tối lúc trời dâm mát, 18,2% không để ý hướng gió. Tỷ lệ người dân vứt chai, lọ, vật dụng hóa chất sau khi phun ngay tại chô phun là 90,5%, chỉ có 1,2% đối tượng đem chôn lấp, 76,1% rửa bình phun tại ruộng/mương. Tỷ lệ các hộ gia đình có cất giữ bảo quản hóa chất bảo vệ thực vật trong nhà là 9,0%, trong đó vật dụng thường được người dân sử dụng để chứa đựng là túi nilon (48,9%); tiếp đến là thùng nhựa 18,8%. Các hoạt động sử dụng, bảo quản hóa chất còn nhiều bất cập, cần có các biện pháp nhằm nâng cao kiến thức cho người dân.
Đánh giá chất lượng và tính ổn định của lô dự tuyển mẫu chuẩn quốc gia vắc xin viêm não Nhật Bản bất hoạt trên tế bào vero chủng Beijing-1 tại Việt Nam
Authors: Lý Nguyễn Thị , Anh Nguyễn Việt , Dung Lưu Thị , Ánh Đỗ Thị Hồng , Hùng Phạm Văn , Hoa Phan Hồng , Hảo Nguyễn Thị Thu , Mai Nguyễn Hoàng , Đạt Đỗ Tuấn , Thiển Đoàn Hữu
Published: April 2021

Trong kiểm định chất lượng vắc xin Viêm não Nhật Bản, mẫu chuẩn là một sinh phẩm không thể thiếu. Tuy nhiên thế giới chưa có vắc xin mẫu chuẩn quốc tế vắc xin Viêm não Nhật Bản bất hoạt trên tế bào. Việt Nam cũng chưa có mẫu chuẩn Quốc gia vắc xin Viêm não Nhật Bản bất hoạt trên tế bào. Do đó, tháng 5 năm 2020 Viện Kiểm định Quốc gia Vắc xin và Sinh phẩm Y tế (NICVB) đã đặt công ty VABIOTECH sản xuất một lô vắc xin Viêm não Nhật Bản (lô BR-520) để làm vắc xin dự tuyển mẫu chuẩn quốc gia. Chất lượng của lô dự tuyển này được đồng thời đánh giá bởi VABIOTECH và NICVB theo các yêu cầu chung cho vắc xin mẫu chuẩn mà Tổ chức Y tế Thế giới (TCYTTG) quy định. Nghiên cứu của chúng tôi nhằm mục tiêu đánh giá chất lượng và tính ổn định của lô dự tuyển mẫu chuẩn quốc gia vắc xin viêm não Nhật Bản bất hoạt trên tế bào vero chủng Beijing-1 tại Việt Nam, bao gồm các tiêu chuẩn xuất xưởng; tính đồng nhất, tính ổn định về công hiệu ở nhiệt độ bảo quản -70oC và ở 4oC, 25oC, 37oC theo các thời gian khác nhau: 1 tuần, 2 tuần, 3 tuần và 4 tuần. Kết quả cho thấy lô vắc xin dự tuyển BR-520 đạt yêu cầu về tiêu chuẩn xuất xưởng; tính đồng nhất về công hiệu, tính ổn định nhiệt theo thời gian và hạn sử dụng có khả năng đến 11,1 năm.
Đột biến trên gen penA và kiểu hình kháng ceftriaxone và cefxime ở một số chủng N. gonorrhoeae phân lập tại Bệnh viện Da Liêu Thành phố Hồ Chí Minh năm 2017 và 2019
Authors: Lan Nguyên Thị Hạnh , Quỳnh Hoàng Ngọc Khánh , Bảo Đường Hạc , Liên Lê Thị , Dương Lê Hà Tầm , Nhi Nguyễn Thị Yến , Hường Lê Thị , Bảo Nguyên Khánh , Ngọc Lê Võ Hồng , Trinh Võ Trần Ngọc , Vân Cao Thị Bảo
Published: April 2021

Cephalosporine phổ rộng (ESC), đại diện là ceftriaxone và cefxime, là nhóm kháng sinh hiện được dùng để điều trị bệnh lậu do vi khuẩn Neisseria gonorrhoeae. Tuy nhiên trên thế giới gần đây ghi nhận sự xuất hiện nhiều chủng giảm nhạy cảm với các kháng sinh này. Cơ chế kháng của N. gonorrhoeae với ESC chủ yếu liên quan đến các đột biến trên gen penA, mtrR, porB1b (penB), ponA,… 50 chủng N. gonorrhoeae giảm nhạy cảm với ceftriaxone/cefxime hoặc cả hai đã được chọn nghiên cứu, nhằm mô tả đột biến trên gen penA và kiểu hình kháng ceftriaxone và cefxime ở một số chủng N. gonorrhoeae phân lập tại Bệnh viện Da liễu Thành phố Hồ Chí Minh năm 2017 và 2019. Kết quả 50 chủng này kháng cao với các kháng sinh dùng điều trị trước đây: ciproﬂoxacin 100%, tetracycline 84%, penicillin 58%. Đồng thời, tất cả các chủng được chọn đều kháng 100% cefxime, 36% trong số đó còn kháng ceftriaxone. Chưa phát hiện chủng kháng azithromycin. 6 chủng đại diện trong nghiên cứu có nồng độ ức chế tối thiểu với cefxime là 1,0 µg/mL cao gấp 4 lần và ceftriaxone ở 0,5 µg/mL cao hơn 2 lần so với chủng đối chứng. Phân tích 6 chủng trên ở mức độ phân tử, chúng tôi xác định được 59 đột biến nucleotide trên gen penA dẫn đến thay đổi 58 axit amin và chen thêm 1 axit amin sau vị trí 345.
Kingdom of Trolls? Influence Operations in the Saudi Twittersphere
Authors: Barrie Christopher , Siegel Alexandra
Published: April 2021

Saudi Arabia has one of the highest rates of Twitter penetration in the world. Despite high levels of repression, the platform is frequently used to discuss political topics. Recent disclosures from Twitter have revealed state-backed attempts at distorting the online information environment through influence operations (IOs). A growing body of research has investigated online disinformation and foreign-sponsored IOs in the English-speaking world; but comparatively little is known about online disinformation in other contexts or about the domestic use of IOs. Using public releases of IO tweets, we investigate the extent of such activity in Saudi Arabia. Benchmarking these tweets to four samples of Saudi Twitter users, we find that engagement with IO accounts was lower than engagement with the average user, but equal to engagement with news accounts. Network analysis reveals that engagement with IO accounts was largely driven by a small number of influential accounts.
The Times They Are Rarely A-Changin'
Authors: Kates Sean , Tucker Joshua , Nagler Jonathan , Bonneau Richard
Published: April 2021

This paper uses geolocated Twitter histories from approximately 25,000 individuals in 6 different time zones and 3 different countries to construct a proper time-zone dependent hourly baseline for social media activity studies.  We establish that, across multiple regions and time periods, interaction with social media is strongly conditioned by traditional bio-rhythmic or “Circadian” patterns, and that in the United States, this pattern is itself further conditioned by the ideological bent of the user. Using a time series of these histories around the 2016 US Presidential election, we show that external events of great significance can disrupt traditional social media activity patterns, and that this disruption can be significant (in some cases doubling the amplitude and shifting the phase of activity up to an hour). We find that the disruption of use patterns can last an extended period of time, and in many cases, aspects of this disruption would not be detected without a circadian baseline.
Ada Salas: la música de los espacios
Authors: Virtanen Ricardo
Published: April 2021

La poesía de Ada Salas presenta, desde los años noventa, una de las calas esenciales de la poesía española contemporánea. Su poesía se ha venido vinculando con diferentes estéticas: poesía del silencio, minimalismo o poesía pura. Este estudio trata la relación de la poética de Salas con el espacio, el silencio y las formas de la música, a través de toda su obra poética.
Talouskuri ja byrokraattinen asiantuntijavalta
Authors: Elomäki Anna , Marttinen Anni
Published: April 2021

Eurooppalainen ohjausjakso on EU:n talous- ja eurokriisin myötä kiristetyn talouspoliittisen ohjauksen keskeinen työkalu, joka on lisännyt EU-instituutioiden mahdollisuuksia puuttua jäsenmaiden talous- ja sosiaalipolitiikkaan. Ohjausjaksoa on kritisoitu talouskurin ja työehtoja heikentävien rakenneuudistusten priorisoinnista, sosiaalisten tavoitteiden alistamisesta taloutta koskeville tavoitteille sekä byrokraattisista ja teknokraattisista prosesseista, joissa demokraattisesti valituilla instituutioilla ja poliittisella keskustelulla on vain pieni rooli. Artikkelin tavoitteena on analysoida, miten ja millaisten mekanismien välityksellä eurooppalainen ohjausjakso vaikuttaa kansalliseen politiikkaan ja hallinnan prosesseihin Suomessa. Artikkeli kysyy, mihin suuntaan ohjausjakso on ohjannut Suomen talous- ja sosiaalipolitiikkaa, millaisia valtahierarkioita ohjausjakson kansallisiin prosesseihin liittyy ja mitkä ovat eri toimijoiden mahdollisuudet vaikuttaa Suomelle annettujen suositusten sisältöön. Analyysi perustuu ohjausjaksoon liittyvään asiakirja-aineistoon ja ohjausjakson keskeisten toimijoiden haastatteluihin.
Incidence and Determinants of Educated-Youth Unemployment in Rajshahi City of Bangladesh
Authors: Osmani Ataul Gani , Islam Rakibul , Rahman Habibur , Amin Al-
Published: April 2021

This study presents the incidence and determinants of unemployment among educated youths in Rajshahi city of Bangladesh. For this purpose, the study analyses primary data collected from randomly selected 250 graduated students of different educational institutions in Rajshahi city by applying two-fold approaches, such as descriptive statistics, and logistic regression analysis. The descriptive statistics approach finds the rate of unemployment among educated youths in the city is 59.2% and the mean duration of unemployment is 2.5 years. The logistic regression results find that the probability of being unemployed will be decreased if the educated youths are migrated to Dhaka city, have internet access, and are connected with social network but if they have job preferences, the probability of being unemployment will be increased. Therefore, institutional facilities, job related trainings, and the development of service sector in Rajshahi city can be crucial solution of the problem.
Russian Foreign Policy in Eurasia and Re-Sovietisation of Ukraine under Putin
Authors: Saira Nawaz Abbasi  , Gul e Hina
Published: April 2021

This research study analyzes Putin's leadership and its efforts for Russianresurgence as a great power. In its desire to achieve its great power statusback; Russia has formed a more assertive foreign policy. Hence, it deemednecessary for Russian policy makers to re-Sovietize its former republics togain its desired objectives. Ukraine appears to be an important state for thecontemporary grand strategy of the Russian Federation. The annexation ofCrimea in 2014, have certain key drivers, such as the large ethnic Russianpopulation with the real grievances that had created instability, which madeRussia step in and intervene. Putin desired to enhance Russia’s internationalstature and deterring Western involvement in its sphere of influence. Russia'sforeign policy goals under Putin have been formulated upon the militaryadventures of the country, especially in its near abroad to engage the postSoviet periphery in geo-economic and geo-political ties with the RussianFederation. Putin seems determined to achieve a central position for Russiaby using his political ideology and leadership as a source of his vertical powerto affluence in the new geostrategic and economic pole of Eurasia. This studyhighlights Putin's keen interest in the former republic of Ukraine that holds avital position that escalated after annexing Crimea while consideringUkraine's importance in the geopolitics of Eurasia simultaneously.
Identity Construction through Cultural Heritage of Folklore
Authors: Ali Ammar  , Tayabba Batool Tahir  , Abdul Razaque Channa
Published: April 2021

The great diversity in Pakistani folklore is evident from the distinguishedvariety of cultural folk assets of each province of Pakistan. The current paperexplores and analyses the most popular folklores, in the genres of both proseand poetry from the perspective of quest for identity. The paper tries to findout the answer to the question if Pakistani cultural heritage of oral traditioni.e., folklores have quest for identity or go beyond that. The paper alsoexplores the motives behind the search for identity. The translated folkloresare then analyzed qualitatively using interpretive method, particularly throughthe perspective of hermeneutic-interpretive research based on performancetheory of folklores. Hermeneutic-interpretive research technique is chosenhere because the folklores are based on the ideological and cultural traditionsof a specific region, and the proper understanding requires the study in thespecific relevant domain of hermeneutics. This research is important for thepropagation, preservation and revival of Pakistani culture as presentedthrough folklores. This research aims at developing the interest and draw theattention of researchers on cultures and traditions to revive and enliven therichness and fertility of varieties in Pakistani culture
Thar Desert and its Natural Resources: A Case Study of the District Tharparkar in Sindh Province of Pakistan
Authors: Zahid H. Channa  , Erum Khushnood Zahid  , Mehwish Bhutto
Published: April 2021

The research study aims to display natural resources of Thar Desert area ofdistrict Tharparkar in Sindh. It is being studied over the years that DistrictTharparkar is totaled as a richest district in natural resources, such as coal,granite, salt mines, china clay, livestock, range land forest and mushrooms.The topography of the District 99% area covered in the desert which is knownas the part of Thar Desert. The Thar Desert existed into two countriesPakistan and India. The discovery of Thar Coal Reserves is one of thesignificant developments in the history of Sindh province of Pakistan whichplaced country at 7th among world top 12 richest coal reserves countries dueto its economic worth. On the basis of the previous studies; it is expected thatThar coal reserves having the potential to solve the energy crisis of Pakistan.The availability of granite is 26.05 billion tons found into 8 to 10 differentcolors in the area of Nagarparkar. Moreover, China clay extracted at 12 to 14different locations and around 2000 people employed in the different fields.Thar Desert of Pakistan has around 120 salt lakes and around 400 laborerswere employed to harvest salt. The Rangeland forests in the desert area of thedistrict represents the main source of livelihood is livestock and the areas arehighlighted the most densely populated in livestock in Sindh province ofPakistan.
Labrador Sea subsurface density as a precursor of multidecadal variability in the North Atlantic: a multi-model study
Authors: Ortega Pablo , Robson Jon I. , Menary Matthew , Sutton Rowan T. , Blaker Adam , Germe Agathe , Hirschi Jöel J.-M. , Sinha Bablu , Hermanson Leon , Yeager Stephen
Published: April 2021

Abstract. The subpolar North Atlantic (SPNA) is a region with prominent
decadal variability that has experienced remarkable warming and cooling
trends in the last few decades. These observed trends have been preceded by
slow-paced increases and decreases in the Labrador Sea density (LSD), which
are thought to be a precursor of large-scale ocean circulation changes. This
article analyses the interrelationships between the LSD and the wider North
Atlantic across an ensemble of coupled climate model simulations. In
particular, it analyses the link between subsurface density and the deep
boundary density, the Atlantic Meridional Overturning Circulation (AMOC),
the subpolar gyre (SPG) circulation, and the upper-ocean temperature in the
eastern SPNA. All simulations exhibit considerable multidecadal variability in the LSD and
the ocean circulation indices, which are found to be interrelated. LSD is
strongly linked to the strength of the subpolar AMOC and gyre circulation, and
it is also linked to the subtropical AMOC, although the strength of this
relationship is model-dependent and affected by the inclusion of the Ekman
component. The connectivity of LSD with the subtropics is found to be
sensitive to different model features, including the mean density
stratification in the Labrador Sea, the strength and depth of the AMOC, and
the depth at which the LSD propagates southward along the western boundary.
Several of these quantities can also be computed from observations, and
comparison with these observation-based quantities suggests that models
representing a weaker link to the subtropical AMOC might be more
realistic.
Quantifying the effects of land use and model scale on water partitioning and water ages using tracer-aided ecohydrological models
Authors: Smith Aaron , Tetzlaff Doerthe , Kleine Lukas , Maneta Marco , Soulsby Chris
Published: April 2021

Abstract. Quantifying how vegetation mediates water partitioning at different spatial
and temporal scales in complex, managed catchments is fundamental for
long-term sustainable land and water management. Estimations from
ecohydrological models conceptualising how vegetation regulates the
interrelationships between evapotranspiration losses, catchment water storage dynamics, and recharge and runoff fluxes are needed to assess water availability for a range of ecosystem services and evaluate how these might change under increasing extreme events, such as droughts. Currently, the feedback mechanisms between water and mosaics of different vegetation and land cover are not well understood across spatial scales, and the effects of different scales
on the skill of ecohydrological models needs to be clarified. We used the
tracer-aided ecohydrological model EcH2O-iso in an intensively monitored 66 km2 mixed land use catchment in northeastern Germany to quantify water flux–storage–age interactions at four model grid resolutions (250, 500, 750, and 1000 m). This used a fusion of field (including precipitation, soil water, groundwater, and stream isotopes) and remote sensing data in the calibration. Multicriteria calibration across the catchment at each resolution revealed some differences in the estimation of fluxes, storages, and water ages. In general, model sensitivity decreased and uncertainty increased with coarser model resolutions. Larger grids were unable to replicate observed streamflow and distributed isotope dynamics in the way smaller pixels could. However, using isotope data in the calibration still helped constrain the estimation of fluxes, storage, and water ages at coarser
resolutions. Despite using the same data and parameterisation for calibration at different grid resolutions, the modelled proportion of fluxes differed slightly at each resolution, with coarse models simulating higher evapotranspiration, lower relative transpiration, increased overland flow, and slower groundwater movement. Although the coarser resolutions also revealed higher uncertainty and lower overall model performance, the overall results were broadly similar. The study shows that tracers provide effective calibration constraints on larger resolution ecohydrological modelling and help us understand the influence of grid resolution on the simulation of vegetation–soil interactions. This is essential in interpreting associated uncertainty in estimating land use influence on large-scale “blue” (ground and surface water) and “green” (vegetation and evaporated water) fluxes, particularly for future environmental change.
Safety and tolerability of liquid amikacin in antibiotic-loaded bone cement – a case series
Authors: Tai Don Bambino Geno , Brinkman Nathan J. , Abu Saleh Omar , Osmon Douglas R. , Abdel Matthew P. , Rivera Christina G.
Published: April 2021

Abstract. High-dose liquid antibiotics are uncommon in bone cement.
We present a case series of patients in which up to 16 mL of liquid amikacin (250 mg mL−1) was successfully incorporated into bone cement to treat periprosthetic joint infections. We did not observe adverse drug reactions
definitively attributed to its use.
Childhood And Adolescent Period Breast Cancer
Authors: Gül Aysel , Aygın Dilek
Published: April 2021

Objective: Breast cancer is a global public health problem which draws attention with the gradual increase in morbidity and mortality rates. Unlike adults, breast cancers in children and adolescents are rarely seen. Since the risk factors are not well defined, cancer findings are mixed with other disease findings and follow-up/treatment processes differ. As a result, childhood/adolescent breast cancers are ignored. It is stated that the prognosis of childhood and adolescent breast cancers is not good, although they are seen in a limited number of patients, the mortality rate is high and it significantly affects the life of the patient and his/her family. The main aim of this compilation is to examine the literature on the pediatric and adolescent breast cancers and the treatment process. Its secondary purpose is to increase the awareness of health professionals and the society and help to create a guideline in this regard to pediatric surgeons, and nurses. Methods: We identified 24 case reports comprising the data of 24 cases of childhood or adolescent breast cancers that were reported between 2000 and 2018. Results: Twenty-four cases (10 males, 14 females) published about breast cancer in children and adolescents were reached. Pathologies of the patients with a mean age of 12.19±4.13 have been reported as secretory carcinoma (70.8%), infiltrative secretory carcinoma (8.3%), malignant phyllodes tumor (8.3%), pleomorphic carcinoma (4.2%), invasive ductal carcinoma (4.2%), secretory adenocarcinoma (4.2%). Modified radical mastectomy was performed in 26.31% of patients with secretory carcinoma, mastectomy in 52.63%, breast-conserving surgery in 10.53%, and wide local excision in 10.53%. While 33.3% of the patients received adjuvant chemotherapy, 29.2% were given radiotherapy. Two patients had recurrence after surgery (3-17 months; median: 10 months). Three patients died due to postoperative metastases. Conclusion: Breast malignancies are relatively rare in the pediatric and adolescent period. However, mortality rates are quite significant contrary to what’s believed. In these patients, difficulties in diagnosing the disease may affect the treatment process negatively. While there isn’t a consensus about the treatment of the disease, the authors reported a wide range of treatments with different combinations of radiotherapy, chemotherapy, breast-conserving surgery, modified radical mastectomy and radical mastectomy.
Effectiveness of Frenotomy in Ankyloglossia Treatment Between 0-1 Years Old
Authors: Akova Fatih
Published: April 2021

Objective: The aim of this study is to present the frenotomy technique in cases of ankyloglossia (tongue-tie), which is diagnosed and treated in the first year of life. Patients were operated by a single surgeon. Method: Cases of ankyloglossia operated at Biruni University Faculty of Medicine Hospital Pediatric Surgery Clinic Between 2016-2020 were evaluated retrospectively in terms of clinical complaints, age, type of ankyloglossia, surgical technique, indications and results of surgery. Results: Frenotomy was performed in 56 patients including 47 boys (84%) and 9 girls (16%), between the ages of 0-1. Average age of the patients was 93 days (1-360). Patients were divided into two groups as Group 1 (n: 40: 0-90 days old) and Group 2 (n: 16: 90-360 days old). Patients were admitted with complaints of having difficulty in sucking the mother’s breast, not being able to take their tongue out, feeding with a bottle, pain at the nipple and not being able to grasp the breast. No additional intervention was required for bleeding in Group 1, and in 12 (75%) patients in Group 2 bleeding control was achieved using bipolar cautery. During follow-up, significant improvement was obtained in all patients who had difficulty in sucking and gripping the nipple. Improvement was observed in 15 of 25 patients with nipple pain. Conclusion: Frenotomy is an easily applied surgical procedure with minimal complications. Additional application may be required for bleeding control in infants older than 3 months. It should be considered that the probability of recurrence may depend on the type, intervention used and thickness of the frenulum, and phrenotomy may not be sufficient. The improvement in breast feeding function of Frenotomy may provide a significant improvement in the complaints of nipple pain, and may contribute to the emotional attachment between the mother and her baby. Randomized controlled trials are required to determine the effects of phrenotomy.
Sistem Penerimaan Beasiswa Pada Universitas Al-Washliyah Labuhanbatu Menggunakan Metode SAW (Simple Additive Weighting)
Authors: Pertiwi Dian , Kusmanto Kusmanto
Published: April 2021

Beasiswa merupakan penghasilan bagi yang menerima dan tujuan beasiswa masalah untuk membantu meringankan beban biaya siswa selama pendidikan atau siswa yang mendapatkan. UNIVERSITAS AL-WASHLIYAH LABUHANBATU adalah salah satu yang memberikan beasiswa untuk mahasiswa setiap tahunnya. Untuk mendapatkan beasiswa, maka diperluka kriteria-kriteria untuk menentukan seorang mahasiswa untuk mendapatkan beasiswa, dibutuhkan sistem pendukung keputusan dengan metode SAW ( Simple Additive Weighting). Metode SAW ini dpilih karena merupakan penjumlahan terbobot untuk mencari penjumlahan terbobot dari rating kinerja pada setiap alternative pada semua atribut. Metode SAW yang dilakukan dengan mencari nilai bobot untuk  setiap kriteria, dan kemudian membuat proses yang akan menentukan peringkat alternative yang optimal adalah mahasiswa yang terbaik  akan dipertimbangkan oleh pengambilan keputusan untuk mendapatkan beasiswa.
Penerapan Analytical Network Process Dalam Menentukan Ras Ayam Serama Simple Additive Weighting (SAW)
Authors: Fahrozi Wirhan , Samsir Samsir
Published: April 2021

Serama chicken is the result of dwarf chicken crossing and is a new type of ornamental poultry currently popular in Indonesia. So it becomes a consideration for lovers of serama to get information about quality of serama chickens that need to get accurate information about quality of serama chickens that still needs to be discussed for the assessment of serama chickens, therefore the author tries to implement it in the form of a Decision Support System in determining chicken breeds as well as by applying the Simple Additive Weighting method to assist in optimal decision making. So that the expected results of the quality of the serama chicken can help in determining the standard of serama chicken assessment.
Perancangan Aplikasi Media Pembelajaran Jarimatika Penjumlahan Dan Pengurangan Berbasis Multimedia
Authors: Syahputra Andrian , Hts Dedek Indra Gunawan , Samsir
Published: April 2021

Perkembangan  Teknologi  terhadap  media  pembelajaran  kini semakin berkembang pesat. Banyak kegiatan pembelajaran yang bisa didukung menjadi lebih efektif, mudah dipelajari  dan menyenangkan dengan menggunakan teknologi, Pembelajaran berhitung pada anak – anak  perlu  ditingkatkan  sehingga   teknik  pembelajaran  ilmu  berhitung  yang  masih monoton, dan mudah menimbulkan rasa bosan, sehingga pembelajaran seperti itu bisa teratasi menjadi sebuah  pembelajaran  yang  efektif,  mudah  dipelajari  dan  menyenangkan. Metode yang digunakan adalah Jarimatika yaitu salah satu metode berhitung dengan menggunakan jari tangan. Minat masyarakat yang tinggi terhadap Jarimatika merupakan potensi yang besar bagi Jarimatika untuk diangkat menjadi media lain yang sesuai bagi anak.  Dengan memanfaatkan teknologi Multimedia membuat aplikasi media pembalajaran jarimatika lebih mudah dipahami karena didalam multimedia terdapat gambar, animasi, suara dan video yang merangkum menjadi sebuah informasi efektif dan interaktif. Belajar berhitung jarimatika penjumlahan dan pengurangan dengan  media pembejaran berbasis multimedia membuat anak akan lebih cepat mengerti tentang penjumlahan dan pengurangan.
Ethnobotanical Significance of Picrorhiza Kurroa (Kutki), a Threatened Species
Authors: Kumari Isha , Kaurav Hemlata , Chaudhary Gitika
Published: April 2021

Herbal plants have been used in the health maintenance customs since the origin of mankind. The herbal products have negligible adverse impacts on the consumer health because they have suitable and beneficial physiological actions on the living systems. Traditional systems of medication primarily use plants in their practices. The market demand of these plant based products has been increased over the past few years. Picrorhiza kurroa Royle ex Benth is one of the most established herbal plants with extraordinary medicinal properties. It belongs to Scrophulariaceae family and commonly called as Kutki. Picrorhiza kurroa is also called as bitter drug due to presence of Kutkin, principle phytochemical constituent of this medicinal plant. It is used in Ayurveda and folk system for treating liver related disorders and used as a remedy for jaundice, malaria, cut, wounds, snake bites etc. Its main therapeutic properties are antimalarial, antidiabetic, hepatoprotective, anticancer, anti-mutagenic, anti-inflammatory, immunomodulatory etc. The aim of present review is to provide information related to phytochemistry, traditional uses in Ayurveda and folk medicinal system and therapeutic properties of Picrorhiza kurroa.

Keywords: Kutki, Kutkin, Rasapanchak, Hepatoprotective, Antimalarial.
Recombinant Oncolytic Poliovirus for Glioblastoma: A Current Review of PVS(RIPO)
Authors: Carpenter Austin B.
Published: April 2021

While the prognosis for glioblastoma multiforme remains grim with a median survival of 12-15 months, PVS(RIPO), a recombinant oncolytic poliovirus, is emerging as a novel immunotherapeutic approach to treat malignancy. PVS(RIPO) is a genetically recombinant poliovirus-rhinovirus chimera that demonstrates antitumor efficacy via two main mechanisms: cytotoxicity and its subsequent immunogenenic response. Here, I review the rationale for oncolytic viruses in the treatment of glioblastoma, the development of PVS(RIPO), the underlying mechanisms of action of PVS(RIPO), the critical preclinical trial that demonstrated its safety and efficacy, the ongoing clinical trials that have shown promising preliminary data, and limitations of PVS(RIPO) as an oncolytic virus for glioblastoma therapy.
RAPID ASSESSMENT ON MACRO-MOTH DIVERSITY AT GUNUNG TAMBORA NATIONAL PARK, WEST NUSA TENGGARA
Authors: Sutrisno Hari
Published: April 2021

Rapid assessment on moth fauna with focus on macro-moths was conducted at Gunung Tambora National Park from 16 to 26 April 2015. The aims of the study were to acquire information on macro-moth diversity and to access the composition of the species at this area. The result showed that a short collecting time within two sampling sites recorded only about 77.8% of estimated value in this park (242 of 311 species). Index diversity based on Fisher’s α is low (97.21). In addition, the number of families recorded from this park is also low, only 17 families, or about one third of the moth families that occur in Indo-Malayan region. Camp II site was higher than the base camp Oi Marai sites in term of the diversity index. These two sites have a few species in common as indicated by Jaccard coefficient that was low (13.8%). In general, Noctuidae (26%), Pyralidae (20%), and Geometridae (19%) dominate across all sites. Noctuidae, Geometridae, Lymantriidae were higher in Camp II than those found in Oi Marai. On the other hand,Pyralidae was higher in Oi Marai than those found in Base Camp II.Keywords: Fisher’s α, index diversity, similarity.
MULTI-AGENT QUANTUM APPROACH TO MODELING OF COMPLEX EMOTIONAL INTELLIGENCE WITH AN ENSEMBLE ORGANIZATION
Authors:   National Research Tomsk State  University, Gorbachev S.V.
Published: April 2021

The paper describes a quantum approach to the modeling of complex emotions based on the integration of paired basic emotions in a 4-dimensional space of signs identified in the psychoevolutionary theory of emotions by R. Plutchik. A modification of the wheel of emotions of R. Plutchik is proposed in order to formalize it in the form of two models of agents of complex emotions – a model with a reactive architecture based on a rule base and an ensemble hybrid model based on various classes of neuro-fuzzy network architectures, which makes it possible to increase the recognition accuracy by 20–30% in multi-agent systems.
EXPERIMENTAL MODELING OF PLANT ONTOGENESIS CONDITIONS AND BIOTECHNOLOGICAL METHODS OF THEIR CULTIVATION IN A CLOSED ECOSYSTEM – SYNERGOTRON
Authors:   Independent NPO Institute for SocioEconomic Strategies and Development  Technologies (Institute for Development Strategies), Latushkin V.V. , Zelenkov V.N. ,   All-Russian Scientific Research Institute of Medicinal and Aromatic Plants, Lapin A.A. ,   Independent NPO Institute for SocioEconomic Strategies and Development  Technologies (Institute for Development Strategies), Vernik Р.А. ,   Independent NPO Institute for SocioEconomic Strategies and Development  Technologies (Institute for Development Strategies, Gavrilov S.V. ,   Independent NPO Institute for SocioEconomic Strategies and Development  Technologies (Institute for Development Strategies), Novikov V.B. ,   Independent NPO Institute for SocioEconomic Strategies and Development  Technologies (Institute for Development Strategies)
Published: April 2021

The use of various closed agrobiotechnological systems (ecosystems) in crop production and agricultural biotechnology is of considerable scientific and practical interest for solving both fundamental (photosynthesis and plant variability) and applied (search for growth regulators and development of biotechnologies) issues in conducting research. The paper presents the results of biological and technological tests in a series of experiments on modeling the influence of plant growth parameters and various technologies for growing salad crops using a prototype of a software-digital device of a closed agrobiotechnological system of the synergotron class of the ISR 1.01 model
ON THE DEVELOPMENT OF SMALL AND MEDIUM BUSINESSES IN THE REGIONS
Authors:   Russian state  humanitarian University, Antonov A.V.
Published: April 2021

The article analyzes the development of small and mediumsized businesses in the Russian Federation for 2017–2020. Forms of support for small and medium-sized businesses are generalized and the main directions of its development in the regions are determined.
N.K. BAIBAKOV – AN OUTSTANDING OILMAN AND ECONOMIST (TO THE 110 TH ANNIVERSARY OF HIS BIRTH)
Authors:   Russian academy of natural sciences, Ivanitskaya L.V. , Arefyev N. V. ,   State Duma of the Federal Assembly  of the Russian Federation, Mozhaev E.E. ,   National research institute of resource conservation and energy efficiency, Lyubimov A.P. ,   Baibakov Foundation for the  promotion of economic development, Markov A.K. ,   National research institute of resource conservation and energy efficiency, Shmakov P.P. ,   Russian Engineering Academy management and agribusiness, Yegorov Yu.N. ,   Russian Engineering Academy management and agribusiness
Published: April 2021

The article is devoted to the life and work of the legendary personality Nikolai Konstantinovich Baibakov. Nikolai Konstantinovich went through a long career from an oil engineer to Deputy Chairman of the government of the USSR. The figure of Nikolai Konstantinovich Baibakov is unique. He became a member of the government under Stalin, and retired under Gorbachev. At the same time, for 22 years he headed the headquarters for the management of the Soviet economy – the state planning Committee of the USSR, where he proved himself as an outstanding economist. His name is associated with major national economic achievements in the development of the country’s fuel and energy complex, industry, and agriculture. For almost a quarter of a century, he defined the strategy and guidelines for the socio-economic development of the USSR.
Civic Life and System Stewardship on the Job: How Can Workers in Every Industry Strengthen the Belonging and Civic Muscle Everyone Needs to Thrive?
Authors: Milstein Bobby , Stojicic Pedja , Auchincloss Ella , Kelleher Christopher
Published: April 2021

Stewardship for well-being is an ancient and still-evolving field of practice concerned with any system that affects who thrives, struggles, or suffers. It is a distinctive way of working across boundaries to reframe how people approach routine work, organizational design, and democratic self-governance. It has been paired effectively with a set of interdependent vital conditions that are the focus of a growing consensus about what produces equitable well-being over time. This article explores how system stewardship, centered on the vital conditions, can drive civic renewal on the job in virtually every industry. We begin by discussing who can become a steward and why stewardship depends on building an inclusive sense of belonging and strong civic muscle. Next, we look at one part of the system for well-being—the American healthcare industry—to illustrate what it takes for industry insiders to step into new roles as civic-minded system stewards. Finally, we consider whether a rising cadre of system stewards could open a viable new path in the movement for well-being and justice.
Grain Refining of Aluminium and 6063 Alloys Using Al-V Alloy Containing Al3V Intermetallic Compound
Authors: MAHRAN Gamal Mohamed Attia , OMRAN Abdel-Nasser Mohamed
Published: April 2021

The grain refinement of aluminium alloys is one of the important processes in various industrial fields. This work aims to use aluminium-vanadium (Al-V) master alloy as a new grain refiner for grain refinement of aluminium alloys. The new refiner was prepared by reduction of vanadium pentoxide V2O5 using molten aluminium, then it was examined using SEM, EDS, XRD, and optical microscopy. The findings of these tests indicated that the developed master alloy contains blocky-shaped particles evenly distributed within the aluminium matrix Al3V in the form of an intermetallic compound. Different levels of vanadium content were examined (3.5, 5.6, and 8.3) as grain refiners for commercial pure Al and 6063 alloys. It was found that the grain size was decreased from 2000 to 320 mm for commercial pure aluminium and decreased from 1500 to 300 mm for 6063 alloys. The best results were obtained by using vanadium content of 0.03 wt.% in the refined alloy and a holding time of 3 min. Based on the gross restriction factor (GRF), the new grain refiner Al-V master alloy performed well at vanadium contents more than 0.02 wt.% in the refined alloy.
Die strafrechtliche Verantwortung von Geschäftsführern für Menschenrechtsverletzungen nach dem Römischen Statut
Authors: Torres Mendoza Frank F.
Published: April 2021

Transnational corporations are accused of involvement in the most serious human rights violations such as crimes against humanity and war crimes. The focus of thise investigation is to answer the question, whether directors of transnational companies can be held criminally responsible for the most serious human rights violations under the Rome Statute. The work focuses on the forms of perpetration, in particular on indirect perpetration by virtue of control over an organisation and complicity as well on the responsibility of civil superiors. In order to justify criminal liability, German criminal law dogmatics are first referred to, especially in the area of participation theory, because it has great importance for the Rome Statute. The author also evaluates the judicial decisions of the ICC and literature and then examines whether these legal figures apply to cases of human rights violations through business activities.
Hepatitis C: An Overview
Authors: Manzoor Kadri Syed , Petkovic Marija
Published: April 2021

Hepatitis C virus (HCV) has infected approximatelly 130–170 milion individuals in the form of chronic liver infection and hepatocellular carcinoma. In the majority of patients with the increased risk for hepatocellular carcinoma the initial rearrangement is fibrosis. HCV is a bloodborne virus. The most common route of the infection are drug use, injections, unsafe health care performance, transfusion and sexual transmission. The incubation period ranges from 2 to 6 weeks in case of HCV. HCV infection is diagnosed in the process of detecting of anti-HCV antibodies and if positive, a nucleic acid test for HCV ribonucleic acid (RNA) is done. Currently, the most promising treatment agents are direct-acting antivirals (DAAs). They have shown limited viral resistance, long treatment duration and higher cost with no proven benefits in the prevention of graft reinfections in HCV individuals. In the light of the aforementioned, there is a need to a more dubious research in the quest for the effective therapeutic modalities.
Quarks Mixing in Chiral Symmetries
Authors: Piotr Szadkowski Zbigniew
Published: April 2021

We discuss a subject of the quarks mixing in SU4∗SU4 and SU6∗SU6 symmetries trying to calculate the quarks mixing angles and the complex phase responsible for the CP non-conservation on the basis of the Gell-Mann Oakes Renner model. Assuming symmetry breaking in a limit of exact sub-symmetries for simultaneous quarks rotations in both electric charge sub-spaces we can estimate all mention above parameters. A perfect agreement of the experimental value of the Cabibbo angles with a sum of simultaneous quarks mixing angles in doublets (u,c) and (d,s) in the SU4∗SU4 symmetry suggests that a quarks mixing is realized in a maximal allowed range. The same assumption used for the SU6∗SU6 and a simultaneous maximal allowed quarks mixing in both electric charge triplets (u,c,t) and (d,s,b) gives a perfect agreement with the experimental value of the Cabibbo angle and estimation on the angles Θ2 and Θ3 as well as a bond for the complex phase δ.
Ants as Indicators of Terrestrial Ecosystem Rehabilitation Processes
Authors: Sithole Hendrik , Tantsi Nolubabalo
Published: April 2021

Habitat transformation is one of the main drivers of the ecosystem degradation on earth that is ameliorated by restoring some of the degraded ecosystems by regaining their natural ecological functions with all their biotic and abiotic components. The biotic and abiotic components of the ecosystem under restoration can be used to assess the response of the ecosystem to the restoration. Ideal variable to use as the indicator should be able respond positively to the diminishing elements that we causing the degradation and interact positively to some of the biotic and abiotic components expected to prevail when the ecosystem is fully restored. One of such variable is ants. We here provide the information about the eligibility of using ants as indicators of terrestrial ecosystems undergoing restoration and sampling and basic analytical methods to apply when implanting ants at assessing ecosystem undergoing restoration.
Ambulatory Surgery for Perianal Disease
Authors: Divizia Andrea , S. Sica Giuseppe
Published: April 2021

The gold standard in the diagnosis and treatment of proctological diseases is the exploration of the anal canal and distal rectum under anaesthesia (EUA), routinely performed as day case surgery. In selected cases it can be conducted as an outpatient exploration (OE) during a specialist surgical consultation. In the outpatient setting it is possible and safe to perform rubber band ligation, sclerotherapy and infrared coagulation for the treatment of haemorrhoidal disease, excision and incision of thrombosed external haemorrhoids, abscess drainage, setonage and fistulotomy also in case of perianal Crohn’s disease, anal warts and skin tags removal. In terms of patients’ satisfaction and success rate OE is comparable to EUA. All procedures can be performed under local anaesthesia. Pain control after the procedure is provided by oral pain killers.
Biochar: A Sustainable Approach for Improving Soil Health and Environment
Authors: Das Shreya , Mohanty Samanyita , Sahu Gayatri , Rana Mausami , Pilli Kiran
Published: April 2021

Current agriculture faces multiple challenges due to boom in food demand and environmental concerns. Biochar is increasingly being recognized by scientists and policy makers for its potential role in carbon sequestration, reducing greenhouse gas emissions, renewable energy, waste mitigation and as a soil amendment. The purpose of this review is to provide a balanced perspective on the agronomic and environmental impacts of biochar amendment to soil. Application of biochar to soil can play a significant role in the alteration of nutrients dynamics, soil contaminants as well as microbial functions. Therefore, strategic biochar application to soil may provide agronomic, environmental and economic benefits. Recent findings also supported that in order to enhance crop yield, improve soil quality and soil health, biochar has proven significant role as fertilizer and soil conditioner respectively.
Docking-Based Screening of Cell-Penetrating Peptides with Antiviral Features and Ebola Virus Proteins as a Drug Discovery Approach to Develop a Treatment for Ebola Virus Disease
Authors: Raoufi Ehsan , Bahramimeimandi Bahar , Darestanifarahani Mahsa , Hosseini Fatemeh , Salehi-Shadkami Mohammad , Raoufi Hossein , Afzalipour Reza
Published: April 2021

Ebola drug discovery continues to be challenging as yet. Proteins of the virus should be targeted at the relevant biologically active site for drug or inhibitor binding to be effective. In this regard, by considering the important role of Ebola virus proteins in the viral mechanisms of this viral disease, the Ebola proteins are selected as our drug targets in this study. The discovery of novel therapeutic molecules or peptides will be highly expensive; therefore, we attempted to identify possible antigens of EBOV proteins by conducting docking-based screening of cell penetrating peptides (CPPs) that have antiviral potential features utilizing Hex software version 8.0.0. The E-value scores obtained in this research were very much higher than the previously reported docking studies. CPPs that possess suitable interaction with the targets would be specified as promising candidates for further in vitro and in vivo examination aimed at developing new drugs for Ebola infection treatment.