bluuebunny/crossref_metadata_2025 huggingface dataset:
Modern preconditions for the prevention and treatment of genetically determined disturbances of folate exchange in marital couples with reproductive disorders
Authors:   SI «Reference center for molecular diagnostics of the Ministry of Health of Ukraine», Kyiv, Rossokha Z. ,   Institute of Genetic and Regenerative Medicine of the National Academy of Sciences of Ukraine, Kyiv
Published: March 2022

The clinical recommendations for the preconceptional consumption of folic acid in married couples during pregnancy planning are analyzed and peculiarities of folic acid status in 206 couples with reproductive disorders are estimated in the article. Hyperhomocysteinemia, due folate related genes polymorphism, was detected in 28.64% patients from couples with reproductive disorders, and in 9.70% of cases – in both of the couples. Folate status of 11.65% patients with 677TT /1298AA genotype compared to other variants of MTHFR gene was significantly different with increasing homocysteine level in blood plasma and decreasing folic acid level in serum. Other cases of hyperhomocysteinemia were due to the heterozygous variants of MTHFR in combination with MTRR, MTR1 genes variants and the effects of additional risk factors. It is necessary to implement a personalized strategy for preconception period planning in married couples with reproductive disorders based on the use of an optimal dose of folic acid of (at least 800 micrograms) in multivitamins (with other vitamins of group B). Key words: reproductive disorder, folic acid, hyperhomocysteinemia, couples, genotype, pregnancy.
Features of subjective manifestations, staging of neoplasia of the genitals in the postmenopausal рeriod
Authors:   Azerbaijan Medical University, Baku, Garashova M.A.
Published: March 2022

The objective: to determine the structure, the stage of detecting ,the severity of subjective manifestations in the presence of tumor processes of the reproductive organs. Materials and methods. A retrospective analysis of case histories of 301 patients with tumors of the reproductive organs in the postmenopausal period was carried out. The average age of patients was 61.6±0.4 years. The duration of the postmenopausal period ranged from 11.0±0.6 years. Results. It was established that 28.9% of postmenopausal women have uterine fibroids, 29.4% have endometrial hyperplasia, 21.6% have endometrial cancer, 10.6% – ovarian cancer, 5.6% – benign ovarian tumors, 5.6% – cervical cancer, 1.7% of patients have uterine sarcoma. In 68.8% of patients, ovarian cancer is diagnosed in the late stages with a predominance of disease detection at stage III of the tumor process (62.5%). Endometrial cancer is diagnosed in 86.2% of patients in the early stages of the tumor process. The frequency of diagnosis of endometrial cancer in the later stages is 4.6%. From the clinical manifestations of genital tumors in postmenopausal, vaginal bloody discharge and/or bleeding, abdominal pain, rapid heartbeat and excessive body hair growth predominate. Conclusion. The results obtained allowed to establish that the postmenopausal period is a period of high risk for the development of neoplastic processes of the reproductive organs. Key words: genital tumors, postmenopausal period, endometrial cancer, ovarian cancer, uterine myoma, uterine sarcoma, endometrial hyperplasia.
Strength and fatigue analysis of periodic perforated materials using the computational homogenization and ES-FEM approaches
Authors: Nguyen Phuong H. , Le Canh V. , Ho Phuc L.H.
Published: March 2022

This paper presents a computational homogenization shakedown analysis of periodic perforated materials with von Mises matrices. The plastic behaviors of the perforated materials under cyclic macroscopic loads are studied by means of kinematic shakedown theorem and computational homogenization method. The kinematic micro-fields are approximated by the edge-based smoothed finite element method. The resulting large-scale optimization problem is efficiently solved by using conic solver, enabling a large number of points on the macroscopic strength and fatigue surface to be calculated rapidly. The effects of the hole's shape and size on the overall strength and fatigue domains are also investigated.
An Experimental study on the processing of two-clause sentences
Authors: Ribeiro Sara dos Santos
Published: March 2022

Some temporal conjunctions can express a variety of meanings on a causal-temporal dimension. By inference, a when-clause may indicate a cause, an event prior in time, or even an event occurring simultaneously with the main clause event (Bever & Townsend, 1970). Using a self-paced reading experiment in the program Psyscope, we crossed the independent variables connective (when) and position (first position – Subordinate-Main – and second position – Main-Subordinate) to test if readers focus more on the main clause than on the subordinate clause and if readers use the order-of-mention strategy to interpret two-clause sentences conjoined with when establishing a causal-temporal relationship. Our results showed a significant effect of both structure and position factors. The online results showed that, in general, the main clause receives more reading times than the subordinate clause and that readers spent more time reading the main-subordinate sentences. The offline results indicate that the information about the first event is easier to recall if the when-clause is the first clause. Thus, the subordinate-main condition presented more accuracy rates. The order of mention strategy did not seem to be used during sentence reading processing, however, the accuracy rates were higher in conditions, in which the linguistic order mirrored the occurrence order. The main-subordinate order affected the ease of late comprehension, although it eased the reading processing.
Oral antibiotic prescription patterns for dental conditions at two public sector hospitals in Pietermaritzburg, KwaZulu-Natal
Authors: Ramnarain P , Singh S
Published: March 2022

Antibiotic resistance is a growing public health concern. Yet, there is a paucity of published data in KwaZulu-Natal on antibiotic prescription trends and patterns related to dental use. The objectives of this study were to identify the range of dental conditions for which oral antibiotics are prescribed at two public health settings (Institution A and B) in the Pietermaritzburg Complex, KwaZulu-Natal and to explore practitioner understanding of the indications for antibiotic prescription for dental conditions. The study used a two-phased approach and collected a combination of qualitative and quantitative data. Phase 1 comprised a retrospective clinical chart review (n=720), while phase 2 comprised a focus-group discussion with purposively selected health care practitioners at each institution. The results of the retrospective clinical chart review indicated that dental abscesses were the most common dental infections requiring oral antibiotic therapy (n= 479; 66%), followed by acute alveolar osteitis (dry socket) (n=110; 15%), dental impactions (n=78; 11%) and dental extractions (n=62; 9%). At Institution A, antibiotic therapy was prescribed for conditions such as trismus (n=13; 6%), soft palate swelling of unspecified origin (n=9; 4%), fibrous epulis (n=6; 3%) and acute herpes simplex (n=2; 1%). Interestingly, antibiotics were not prescribed at Institution B for the same dental conditions. Antibiotic therapy was also prescribed for eruption pain (n=4; 1%) and for cases when patients did not bring their inhaler for asthma treatment (pump) (n=3; 1%). The findings from the focus-group discussions suggested that there is a need to improve practitioner understanding of the indications for antibiotic prescriptions for dental conditions. This study showed some differences in antibiotic therapy prescription patterns at the two public health institutions, especially for dental conditions that did not require such management. This suggests a need for consensus building among health professionals and the provision of more dedicated guidance for antibiotic prescription in the management of dental conditions.
Can you afford to smile? The Economic disparities in oral health care provision
Authors: Sykes Leanne , Cronje Amelia , Mmutlana Idah
Published: March 2022

Tooth loss can have a negative impact on a patient’s quality of life. However, many patients cannot afford the treatment necessary to restore their dentition optimally. Their final choice may be dictated by what they can afford rather than consideration of the advantages, disadvantages or biological sacrifices associated with proposed options. At the same time, clinicians often express feelings of helplessness and stress when confronted with having to decide on, and provide treatment that is within the patient’s financial means, rather than according to what they deem to be “best practice”. This paper uses a patient case to illustrate how the four-principle approach proposed by Beauchamps and Childress (1983) can be used during treatment planning, and to justify the final decision making process.
[RETRACTED] Mike Wolfe CBD Gummies Shark Tank Scam Reports 2022 v1
Authors: not provided mikewolfesharktank
Published: March 2022

[RETRACTED]

Mike Wolfe CBD Gummies Shark Tank Scam Reports 2022
Affordable Futures Past: Rethinking Contemporary Housing Production in Portugal While Revisiting Former Logics
Authors: Lameira Gisela , Rocha Luciana , Ramos Rui Jorge Garcia
Published: March 2022

This article focuses on a specific term associated with the scientific, theoretical, and academic discourse on housing architecture in Portugal. Over the last 100 years, the term “affordable” has frequently been used in the vocabulary of urban housing in Portugal, being linked to other words commonly used in housing construction, such as económica (economical), barata (cheap/inexpensive/low-cost), pobre (poor), cooperativa (cooperative), or even custos controlados (controlled costs). Therefore, we propose to explore the multiple appropriations and contemporary shifts in its original meaning, seeking in this way to: (a) further stimulate the contemporary discussion on types of buildings, public housing programmes (i.e., following a historical perspective), contemporary housing policies (e.g. Basic Housing Law and New Generation of Housing Policies), refurbishment policies, new regulations, and new models for the middle classes (in Portugal); (b) share perspectives about the updating of this concept and the materialisation of its respective types and models in contemporary architectural practice; and (c) build bridges between the past and the present (public and private models and solutions, and shifts in the target audience). Although a wide range of different words was used to describe “affordable housing” in Portugal from the early 20th century to the first decade of the 21st century, it is essential to stress the importance of several newly emerging concepts. In recently implemented laws, concepts such as economicamente acessível (economically accessible) and custos controlados (controlled costs/low-cost) encompass the shifts in the meaning of the term “affordable” and broaden the contemporary discussion of the housing problem in relation to the type of property and target audience.
gramática de construções diassistêmica
Authors: Jr. Roberto de Freitas , Soares Lia Abrantes Antunes , Nascimento João Paulo da Silva , Da Silveira Vitor Luiz Vieira
Published: March 2022

O objetivo do presente artigo é abordar a discussão sobre aquisição de L1 e L2, a partir dos princípios teóricos da Gramática de Construções Diassistêmica (GCxD) - (HÖDER, 2018) - e da Gramática de Construções Baseada no Uso (GCBU) – (GOLDBERG, 2019): modelos de pressupostos construcionistas sobre o processamento e a realidade psicológica do conhecimento linguístico, seja de uma L1 e/ou de uma L2. Para essa discussão, dividimos o texto em duas partes. Na primeira, revisamos alguns princípios dos modelos abordados. Na segunda, ilustramos questões teóricas, a partir de dados e resultados advindos de pesquisas com foco no conhecimento gramatical de falantes não nativos do português brasileiro (PBL2) e do inglês (IL2). Os dados instanciam os padrões (i) [(ESP) N] – a construção de especificação nominal – no contexto de aquisição do PBL2 e (ii) [(X) VSN] – a construção de focalização por posposição de sujeito – no contexto de aquisição do IL2.
Colocação Pronominal no Português Brasileiro de Nova Iguaçu
Authors: Martins Ana Luísa Theza , Vianna Juliana Barbosa de Segadas
Published: March 2022

Nesta pesquisa, investiga-se o fenômeno variável da posição dos clíticos pronominais, em lexias simples, a partir de amostras de fala e escrita coletadas na cidade de Nova Iguaçu (RJ). Adotando o referencial teórico da Sociolinguística Variacionista, pretende-se determinar os fatores sociais e linguísticos que condicionam o uso da próclise em detrimento do uso da ênclise nas modalidades oral e escrita da língua, além de reconhecer quais são os elementos proclisadores tradicionais e não tradicionais mais frequentes junto ao uso da próclise. De acordo com a análise de dados, foi possível trazer as seguintes afirmações: (a) a próclise mostrou-se mais produtiva que a ênclise, principalmente em língua oral; (b) o grupo de fator tipo de elemento proclisador foi o grupo que mais influenciou a colocação pronominal nas duas modalidades da língua (oral e escrita); (c) o grupo de fator escolaridade do falante, apesar de não ter sido controlado em língua escrita, também mostrou-se relevante para a colocação pronominal; e (d) alguns outros fatores linguísticos mostraram-se relevantes, no entanto, de forma divergente nos dados de fala e escrita, mostrando que suas influências dependem do contexto linguístico em questão.
Tedavi Sürecindeki Bağımlıların Sentetik Kannabinoid Kullanım Özellikleri ve Algıları
Authors: Özcan Yasemin Sanal
Published: March 2022

Objective: Knowing by whom, in what form a substance is consumed, with which substances it is consumed with, the frequency of use, the effects it creates on the user and the expectations from the use significantly affect the effectiveness of the fight against these substances. It was aimed to reveal the socio-demographical characteristics, adaptation problems, suicidal attempt and self-harm behaviors, synthetic cannabinoid use histories, patterns and effect expectations as well as the perceptions of synthetic cannabinoid (SC) users.
Methods: It was conducted through one-to-one interviews with 70 male patients who were receiving substance abuse treatment.
Results: 41% (n=29) of the participants were unemployed and 60% (n=42) of them dropped out of school. They encountered problems such as caries (7.1%) and discipline (17.1%) during their military service. And it was observed that there were 71 crimes that 51 of the participants were associated with. The first drug used by the 12.5% (n=9) of the participants is synthetic cannabinoid. 24% (n=17) of them applied to the emergency department due to negative side effects they experienced due to SC use. 5.7% of respondents have little or no hope of stopping SD use.
Conclusion: It was observed that the participants had problems in adaptation in education and military service processes; experienced intense legal problems, and had health problems due to substance effects. It is believed that both the improvement of preventive/therapeutic studies and the need to inform health and legal pesonelle about the users and effects of synthetic cannabinoids is substancial.
Tekrarlayan İntihar Girişimlerinin Sosyodemografik Özelliklerinin ve Sonuçlarının İncelenmesi:Ankara İli Örneği
Authors: Kabadayı Şahin Esra , Şan İshak , Bekgöz Burak , Albay Burhan
Published: March 2022

Objective: Suicide re-attempt is one of the strongest predictive factors of completed suicide. The aim of this study was to evaluate the socio-demographic data and the results of repeated suicide attempts in the 112-command center of Emergency Services.
Methods: The socio-demographic characteristics related to suicide attempts of the patients aged 15 and over applied to the Ankara 112 command center of Emergency Services for recurrent suicide attempts between 2017-2019 were examined through electronic records.
Results: There were 8231 applications due to suicide attempts in three years in Ankara province and 847 of them (10.3%) were recorded as recurrent suicide attempts. A total of 344 people who attempted recurrent suicide were 62.5% male and 37.5% female. The vast majority of those who had recurrent suicide attempts were found to have attempted suicide twice (79.9%). The rate of completed suicide among recurrent suicide attempts was 1.5%, all of them were the result of the second suicide attempt. The most common suicide attempt method was drug and chemical use in both sexes, and the most common methods used in completed suicides were firearms and medication/chemical use. According to the seasons, days or hours there was no statistically significant difference between genders or suicide attempts and completed suicides.
Conclusion: This is the first study that reports the socio-demographic characteristics of recurrent suicide attempts in our country. In addition to the interventions to recurrent suicide attempts, it is also important to develop preventive and protective strategies for high-risk groups vulnerable to making first suicide attempts.
Pitbull Cinsi Köpek Saldırısında Ağır Yaralanan Kız Çocuğunun Adli Tıbbi Açıdan Değerlendirilmesi: Olgu Sunumu
Authors: Aslan Fatmagül , Timur Serdar , Teke Hacer Yaşar , Kurt Zeynep Aylin
Published: March 2022

In the field of forensic medicine; injuries due to biting can be encountered in a wide range from mild to severe - even causing death. Animal bites are common nowadays and especially affect children. Although not common, such injuries draw attention with the findings of negligence and abuse, and even deliberate injury. In this study, a pediatric case who was bitten by a pittbull dog from various parts of his body, thrown by shaking and treated in intensive care is presented. It was aimed to discuss the forensic medical responsibilities of the Forensic Medicine Units in this and similar negligent injuries, especially by evaluating the case whose opinion was requested in terms of negligence, abuse and deliberate injury due to an incision in the throat.
Adli Bilimlerde Adli Tıp ve Adli Tıp Dışı Alanların Türkiye’deki Yapılanması ile ilgili Sorunlar: İki Rapor ile Değerlendirme
Authors: Doğan Muzaffer Berna
Published: March 2022

Forensic science is a superstructure that includes many branches that require special expertise. The correct application of these branches that require expertise to the practice requires a unique organization. The way to establish an organization in this way is strictly dependent on evaluating the problems from both inside and outside. For the holistic approach to the problems related to forensic science and forensic medicine organization in Turkey, current literature on the subject was studied and two resources have been reached. The first of these is a study prepared by the Presidency State Supervisory Board (DDK) in 2010. The main perspective in this study is to provide European Union norms. The other study is a report titled "Forensic Medicine Service Model and Manpower Planning" prepared by Prof. Dr. Yasemin Balcı, after being discussed by the Board of Proficiency in Forensic Medicine and accepted on 7 April 2007. Although many researches have been carried out on the field until today, these two reports come to the fore in which many areas and issues are discussed extensively and recommendations are made. It is seen that the problems stated in these detailed reports evaluated within this scope, there are deficiencies in the implementation of the structures and regulations proposed to solve the problems. For this reason, first of all, any regulation and structuring that has been made to solve the problems stated in these reports has been discussed when necessary.
Geleceğin Hekimleri Etik İkilemle Karşılaştıklarında Nasıl Davranacaklar? Adli Tıp Staj Rehberliğine Bir Bakış
Authors: Yıldız Abdulkadir , Gürpınar Süleyman Serhat , Eroğlu İbrahim , Cinkara Osman , Aldemir Fatma Nur
Published: March 2022

Objective: In this study, the guidance of forensic medicine education to medical students on ethical dilemmas and its effect on their attitudes and behaviours on ethical approach were examined, at the same time, common ethical dilemmas tried to be solved through discussion.
Methods: A survey, trying to determine the attitudes and behaviors of the students in the face of possible scenarios including ethical dilemmas in their medical professional life, was applied on 111 volunteer participants covering fifth semester medical students. “SPSS for Windows 17.0” package program was used to analyze the acquired data.
Results: It was observed that medical faculty students taking forensic medicine internship training stated that they would present a statistically significant level of ethical approach compared to those not taking forensic medicine internship training in all six scenarios with ethical dilemma (Scenarios 1, 2, 4, 5, 6 p<0.01 / Scenario 3 p<0.05).  
Conclusion: Ethical dilemmas are the significant issues that a physician will often encounter throughout his career. Physicians should solve these dilemmas by knowing about their ethical responsibilities and the national and international regulations on these responsibilities. Thus, teaching about the medical ethics and these regulations in medical education have a particular importance. It was thought that there should not be such a significant difference of an ethical approach among the students in the same period of their education process. Since ethic is the common ground of all medical branches, each branch should include the education of ethic in its curriculum.
Travma Skorlama Sistemlerinin Adli Raporlarda Yaşami Tehlikeye Sokan Yaralanmanın Şiddetini Ayırt Etmede Kullanılabilirliği
Authors: Şenavcı Murat , Erel Özlem
Published: March 2022

Objective: Our study was carried out in order to evaluate the trauma scores used for forensic trauma cases according to the recommended guidelines. In the report were trauma resulting in death or majör life threatening situation the trauma scoring system is used to compare the impact of the trauma on ones life threatening situation.
Methods: In this study, forensic traumatologic reports of 1684 cases were examined.
Results: Sensitivity 75.6%, selectivity 99.1% for AIS optimal cut point 3, sensitivity 72.6% for ISS optimal cut point 9, selectivity 99%, sensitivity 14.6 for RTS optimal cut point 7,0061, The selectivity was calculated as 99,7, the sensitivity for CRAMS optimal cut point 8 was 13.5%, the selectivity was 99.9%, for TRISS the most suitable cut point was 93.610, the sensitivity was 23.4% and the selectivity was 99.7%. Patient groups between 0-17 years; sensitivity 76.1% for AIS optimal cut point 3, selectivity 99.2%, ISS 75% for selective cut point 9, selectivity 99.2%, sensitivity for RTS optimal cut point 7.4745 83.3% , selectivity 85.9%, CRAMS optimal cut point 9 for sensitivity 87.5%, selectivity 86.8%, TRISS optimal cut point 98.95 for sensitivity 95.7%, selectivity 93.7%, PTS optimal The sensitivity for cut-off point 9 was 96.7%, and the selectivity was 97.3%.
Conclusion: It was found that TRISS and PTS trauma scoring systems have benefits especially in terms of standardization, but should be approached carefully in terms of their limitations in order to determine the severity of the disease and the possibility of mortality in traumatized patients.
El valor y la importancia política de los grupos vulnerables
Authors: Macioce Fabio
Published: March 2022

La noción de grupo vulnerable es tan utilizada en los textos normativos como criticada en la literatura filosófica y política. Este artículo analiza las críticas que se han dirigido a esta noción y propone, alternativamente, dos posibles modalidades para su interpretación. Las dos posibles acepciones de la vulnerabilidad de los grupos son capaces de responder a las críticas —en particular, las relacionadas con un enfoque esencialista y con los riesgos de estereotipación— y permiten mostrar el valor positivo que puede tener la vulnerabilidad de los grupos, especialmente en el plano político. El artículo tiende a mostrar que la dimensión colectiva de la vulnerabilidad puede tener un efecto habilitante y positivo, y es fundamental para desenmascarar los sistemas de poder y opresión que tienden a marginar a las personas en condiciones de vulnerabilidad.
Racionalidad extractivista y necropolítica de la expropiación patriarcal: un acercamiento al estudio de las masculinidades para re/pensar el poder del extractivismo
Authors: Cortés-Cortés Ramón , Zapata-Martelo Emma
Published: March 2022

Extractivism is a mode of exploitation that implies a particular rationality product of the process of modernity/coloniality. Through feminist research, the purpose of this work is to rethink the extractive power by means of providing the conceptual basis for the analysis of masculinities in these contexts through the categories of gender, work, and violence. At the same time, the modern-colonial rationality, under which extractivist enclaves emerge to fragment and commercialize territories, is revealed to occur through what we call necropolitics of patriarchal expropriation. The patriarchal pact between hegemonic masculinity, and complicit and subordinate masculinities, broadens and deepens gender inequalities in extraction territories. Carrying out an analysis of masculinities in extractive sites allows us to understand the advance of extractivism, and the place occupied and disputed by male gendered subjects in the system of gender relations.
Ecoturismo, campesinos, selva y residuos de guerra en la Amazonia colombiana: una mirada a través de la ecología afectiva
Authors: Montenegro-Perini Iván
Published: March 2022

Ecotourism became one of the most important sectors on Guaviare's government agenda since the 2000s. Through its trainings, it would seek to turn coca growers into environmental-entrepreneurial subjects, and the Amazon into an untransformed resource that generates value. With the concept of affective ecologies, I explore the relations that took place between the ecotourism, peasants, the forest, and the residuals of war in Guaviare between 2005 and 2018. In doing so, I argue that, although peasants reproduced the types of subjectivity and nature of institutional ecotourism that operate in the society-nature divide, they also exceeded them. In this way, I reflect on the capacities that the concept of affective ecologies can have to trace and think alternative ways of life without capturing them within the modern conceptual framework of environmental policies and of what some refer as the properly political.
La deuda en juego: una lectura de-colonial de Los juegos del hambre
Authors: Casals-Hill Andrea
Published: March 2022

In this article, I propose to understand the insights of 20th century Latin American intellectuals on environmental injustice and its connection to colonialism and neo-colonialism as a reading apparatus to expand —and even subvert— the symbolic meaning of popular dystopian narratives such as The Hunger Games (2008) and its prequel The Ballad of Songbirds and Snakes (2020) by Suzanne Collins. I assert that reading these narratives as an allegory of the exchanges between the Global South and the Global North exposes blind spots of the latter regarding its performance and responsibility in the ever-growing ecological debts and the footprint of extractivism in the South. I complement this allegoric reading by comparing both novels from Paulo Freire’s critical hope perspective, which re-signifies the novel by understanding it as a narrative sketched out by utopian thought, not as a postapocalyptic dystopia; that is, read from a present that we can transform.
A Guide to the Seedlings of New England
Authors: Robertson Jo
Published: March 2022

A guide to the seedlings of Vermont for Forest Health Monitoring
Endodontic management of a case of radix entomolaris: A case report
Authors: Shorey Priyanka , Sidhu Kitty
Published: March 2022

Mandibular molars can have an additional root which can be located lingually (the radix entomolaris) or buccally (the radix paramolaris). An awareness and thorough understanding of this unusual anatomical feature can lead to a successful endodontic treatment of a tooth. This case report describes the case of a radix entomolaris found in a mandibular first molar and discusses its diagnosis and further endodontic management.
An analytical study on the ocular manifestations of autoimmune blistering skin disorders, in patients attending a tertiary care hospital
Authors: Vinupal Anupama
Published: March 2022

Autoimmune blistering skin diseases are a heterogeneous group of diseases that have as their common feature autoantibodies directed against desmosomal structural proteins. They can sometimes affect the eye, with manifestations ranging from mild to potentially vision threatening.

To evaluate the spectrum and incidence of ocular manifestations and to analyze whether early ophthalmological examination will be beneficial in reducing ocular morbidity.rn

Hospital based analytical study conducted at Coimbatore Medical College and Hospital, Coimbatore, Tamil Nadu.

This study involved 100 patients diagnosed with autoimmune blistering skin disorder attending Dermatology and Ophthalmology outpatient department and included a comprehensive ocular examination of the patients.

The collected data were analysed with IBM.SPSS statistics software 23.0 Version. To find the association of significance in categorical data the Chi-Square test was used. In the above statistical tool, the probability value .05 was considered as significant level.

Autoimmune blistering skin diseases were associated with a significant proportion of ocular manifestations, of which in this study, dry eye and conjunctivitis were the most common.

Dry eye and conjunctivitis were the most common ocular manifestations in this study. Though none of the patients had vision threatening manifestations, a comprehensive ocular examination and follow up of these patients is necessary.
A clinical study to evaluate recurrence of pterygium after primary surgery and its management
Authors: Khandelwal Divya , Walia Shweta , Kori Neetu , Bhaisare Vijay , Rawat Preeti , Gautam Manushree
Published: March 2022

Recurrence is a significant problem after pterygium excision. Therefore in this study its risk factors and management is discussed.

This study was conducted to observe recurrence after conjunctival limbal autograft (CLAU) & to evaluate different factors related with recurrence of pterygium and assessing its different management methods.

Hundred & seven patients with primary pterygium were examined, excised by CLAU and histopathology sample sent. The outcomes were assessed in terms of clinically significant recurrence till 6 months follow-up. Early topical mitomycin-C (MMC) 0.02% QID for a week was given to avoid resurgence of clinically significant pterygium, however if developed then excised by CLAU (if <4mm) or AMG (Amniotic membrane grafting) (if > 4mm).

Out of total cases, 57% were females. Histopathology findings includeEpithelial Hyperplasia (80.4%), vascularity overwhelms fibrosis (39.1%), vascularity similar to fibrosis (28.3%), fibrosis overwhelms vascularity (34.8%), perivascular stromal inflammation (54.3%), diffuse stromal inflammation (37.0%). The following variables were significantly associated (p<0.05) with the recurrence: age, redness & thickness, higher vascularity, diffuse inflammation.

Factors such as younger age group, higher redness and thickness of pterygium, more vascularity, and diffuse inflammation on histopathological examination can be considered as a risk factor for recurrence. However, occupation, location, and type of pterygium were found not to be related to recurrence. Although no clinically significant recurrence was seen after mitomycin c eyedrops, but no significant correlation can be made.

Young patients having pre-operative features like red and fleshy pterygium, along with vascularity more than fibrosis and diffuse inflammation on histopathological examination should be followed strictly and managed intensely.
Current scenario of ocular morbidity in severe acute childhood malnutrition in central part of India
Authors: Raichandani Divya , Kumar Kavita , Dubey Aditi , Morskole Sheetal , Tyagi Shreya
Published: March 2022

The study aimed to assess the prevalence of ocular involvement in children 6 months to 5 years attending tertiary care centre with Severe Acute Malnutrition and to detect the associated risk factors for ocular morbidity in severe acute malnutrition.

: This hospital based observational study was carried out at Gandhi Medical College, during the study period of 2 years on children diagnosed with SAM belonging to 6 months to 5 years of age. Detailed history was obtained and physical, systemic and ocular examination was done.

: A total of 100 severe acute malnourished children were included. Prevalence of ocular involvement in severe acute malnourished children was 72%. Conjunctival pallor was observed in 71.5% eyes and retinal hemorrhages were most common posterior segment finding. Vitamin A deficiency signs were observed in 17 eyes (8.5%). Higher birth order and number of sibling was significantly associated with higher incidence of ocular manifestations (p<0.05). However, other variables showed no significant association between other variables and ocular manifestations (p>0.05).

Training should be given to health workers at the primary health care level and health centers on counseling mothers on feeding, growth monitoring, the preventable eye blinding diseases and hygiene during the vaccination sessions and early referral of children with eye signs to hospitals. Also education of couple regarding proper nutrition of mother and child should be encouraged and couples should be insisted to have not more than two children.
A study of orbital mucormycosis cases at a tertiary hospital
Authors: Phalke Snehal , Pande Arundhati
Published: March 2022

The aims of this study was to identify demographic data risk factors for the disease, clinical presentation and treatment outcome of patients having COVID-19 related mucormycosis.

This was a prospective, interventional study done in a tertiary hospital carried out from May 2021 to July 2021.

With 40 patients under study, the mean age of patients was 52.4 years. The incidence was more in males (80%) than in females. 95% patient had history of COVID-19. In these patient, the treatment of COVID-19 received were either Steroids (92%), O2 therapy (57.5%) or had an ICU stay (37.5%). T2DM was present in 62.5% while T1DM in 2.5%. These patients mainly received intravenous amphotericin-b (92.5%) along with syrup posaconazole as medical management. functional endoscopic sinus surgery (FESS) was done in all the patients while maxillary debridement or maxillectomy was done in 42.5% patients. In ophthalmic conservative line of management 37.5% received transcutaneous retrobulbar amphotericin B (TRAMB). 10% patients underwent exenteration who presented in later stages of the disease. Inspite of all the interventions, 22.5% succumbed due to low health conditions.

Corticosteroids followed by DM were the commonest pre-disposing factor for COVID-19 related mucormycosis. Early FESS and timely TRAMB reduced the spread of the disease and conserved vision respectively.
Rise & review of invisalign clear aligner system
Authors: Wajekar Nimish , Pathak Snehal , Mani Shubhangi
Published: March 2022

This review article will discuss Invisalign (Align Technology, Santa Clara, Calif) product in depth. How this system has evolved since it has been launched, how it differs from other clear aligners, why the results with Invisalign are more predictable than other clear aligner therapy and how Invisalign has managed to achieve these results. Advantages, disadvantages and its limitations. Aligners in COVID-19 pandemic. As clear aligner therapy is gaining more and more popularity among adult patients this article might be useful for orthodontist who are planning to incorporate Invisalign and clear aligners in their practice.
Microbial corrosion of orthodontic wires
Authors: Sharma Vipul Kumar , Yadav Gitanjali , Chaturvedi TP , Upadhyay SN , Tilak Ragini
Published: March 2022

To evaluate microbial corrosion by weight loss, microbial corrosion and elemental analysis of NiTi and stainless wires after period of 2 months in streptococcus mutans containing media.

Percentage change in weight after 2 months is 1.7% and 0.8% in NiTi & SS respectively. Elemental analysis of NiTi wire in streptococcus containing media showed decrease in Ni by 2.9% by weight and Ti decreased 3.07% by weight due to leaching of Ni and Ti from the surface of wires. In stainless steel wire, there was decrease in Fe by 8.82% and Cr 1.39% by weight.

Significant microbial corrosion was observed in NiTi wires as compared with SS wires may be attributed to the surface roughness of NiTi wires. However, the role of biofilm is dual and remained controversial due to being protective and corrosive.
Assessment of inflammatory status of peri-implant soft tissue around functionally loaded immediate implants placed in periodontally compromised tooth extraction sockets
Authors: Elizabeth Kuruvilla , Biniraj K R , Rishi Emmatty , Tony Paul P , Priya Jose , Divyasree K A
Published: March 2022

The present study was aimed at assessment of the soft tissue condition around immediate implants used to replace periodontally compromised mandibular anterior teeth.

A longitudinal study was conducted on 17 functionally loaded immediate implants placed in periodontally compromised sockets at mandibular anterior region. Clinical and biochemical assessment of inflammatory status of peri-implant mucosa were recorded at 2 week, 6and 12-month intervals after loading. Clinical parameters included modified Plaque Index (mPI), modified Bleeding Index (mBI), marginal soft tissue level (ML), Papilla Index (PI) and width of attached mucosa (AM). Biochemical parameter was the levels of Aspartate aminotransferase (AST) enzyme in peri-implant crevicular fluid (PCF).

Inter-comparison of observations were statistically analysed using repeated-measures ANOVA. The mean mPI score was 0.71, 0.41 and 0.53 at three intervals (p=0.354) indicating moderate score. The mean mBI was1.06, 0.35 and 0.29 at various intervals (p=0.000), pointing reduced bleeding tendency. Throughout the study, 70.588% of sites had positive ML, suggesting soft tissue stability. Mean PI scores were 1.71, 2.06 and 2.65 and for AM were 2.41, 2.41 and 2.94 respectively at the three intervals, with a statistically significant p-value of 0.000 for both. The mean AST level in PCF was 1876.47 μIU, 1729.41 μIU and 2117.65 μIU (p=0.431), pointing no increase in inflammation.

Considering the results obtained, implants under study exhibited no major inflammatory changes in the soft tissue, during the study period.
Tetracycline fiber: A drug in your pocket
Authors: Maurya Dilip Kumar , Pant Vandana A , Aamir Mohammad
Published: March 2022

Periodontal disease is a broad phrase that refers to a variety of diseases that damage the tooth

: Different mechanisms and ways to medication release in the periodontal pocket are used in local drug delivery. Such technologies deliver the medicine directly into the periodontal pocket and provide up to 11 days of continuous release.

: This study exhibited that albeit careful SRP is a successful therapy technique for disposal of chronic periodontal pockets, further developed outcomes can be acquired by adjunctive utilization of locally controlled antibiotic medication tetracycline fibres and others such products.
Design and Measurement of a Modern Charging System Based on IoT
Authors: Saheb Ahmed M. , Farhan Bashar Sakeen
Published: March 2022

This paper presents a modern charging system to improve the reliability of locating the closest and available free charging slot to charge low-power smart-devices. Also, the presented system is based on the cloud and the used network is based on the internet of things technology. The basic idea of the charging system is to provide a public charging place for all individuals who wish to charge their smart devices when it is close to running out. First and foremost, the charging system was designed and implemented to have multiple power sources in the event that one of the system's power sources failed. Secondly, the charging system provides a special smart mobile application that has also been designed and implemented, which allows the user to know the locations of the charging systems on a map and choose the nearest available system near the user. After selecting the nearest charging system, the user will be able to know whether or not there is an available charging port and the number of associated devices in each system. The study successfully built this system in practical life.
Coupled Thermodynamic Analysis on the Fire Response and Improvement of Fire Resistance of Steel Buildings
Authors: An Jingbo , Wang Chunhong
Published: March 2022

The poor fire resistance of steel buildings threatens structural security, and severely limits the application of such buildings in many countries. The existing studies have not carried out whole-process analysis on the temperature field distribution and deformation law of steel building components under fire. To solve the problem, this paper performs coupled thermodynamic analysis on the fire response of steel buildings, and tries to improve their fire resistance. Firstly, the dynamical properties of steel buildings in response to fire were analyzed, and a coupled thermodynamic model was constructed for these buildings. Next, the whole process of thermodynamic coupling was investigated for the fire response of steel buildings. Through experiments, the authors obtained the results of coupled thermodynamic analysis, and presented suggestions on how to improve fire resistance.
Temperature Field and Thermal Deformation of Steel Structural Members in Construction Engineering
Authors: Cheng Jian
Published: March 2022

The steel structure is increasingly applied in various building structures. It is of theoretical and practical significance to study the non-coordinated temperature field effects between the steel structure and external structure, and the strongly uneven temperature stress and marked deformation that ensue. However, the thermal boundary conditions are complex in the existing studies. Thus, this paper analyzes the temperature field and thermal deformation of steel structural members in construction engineering. Firstly, the relevant parameters were enumerated for the basic heat transfer modes, the temperature field of the steel members was calculated simply, and the convective heat transfer coefficients (CHTCs) of the members were discussed under different cross-sections and wind directions, presenting the accurate solution to thermal convection. Next, the thermal deformation of steel structural members was investigated to construct the thermal deformation equation of conventional steel structural members. Finally, experiments were carried out to compare the effects of different heat transfer parameters on the temperature stress of the components, and to summarize the entire process of building a thermal deformation equation for steel structure components.
Heat Transfer and Pressure Drop Performance of a Hydraulic Mining Shovel Radiator by Using Ethylene Glycol/Water-Based Al2O3 Nanofluids
Authors: Canazas José , Kamyshnikov Oleg
Published: March 2022

Nanofluids are excellent replacements for vehicle radiator coolants and they have the ability to significantly enrich the performance of vehicle radiators. A numerical study of thermal and hydraulic performance of a hydraulic mining shovel radiator working with nanofluids is carried out. It is observed so far that there are no research works done before analyzing the radiator of this mining equipment. Aluminum oxide in ethylene glycol as nanofluid with volume concentrations of 0.5%, 1.0% and 1.5% were investigated. The results showed that the heat transfer performance of the radiator can be hindered if thermal operating parameters of the equipment are not varied to take advantage of the benefits done by nanofluids. Additionally, it has been found that the pressure drop performance on the radiator operating in laminar and transitional conditions can reduce pressure drop and therefore pumping power. The analysis presented in this paper concluded that the use of nanofluids essentially depends on thermal and flow conditions.
Numerical Analysis of Central Solar Receivers with Various Geometries
Authors: Kulkarni Kaustubh G. , Havaldar Sanjay N. , Malapur Harsh V.
Published: March 2022

Concentrated solar power (CSP) is a cutting-edge method of conserving renewable energy. The concentrated solar power is utilized as a heating source to increase the temperature of heat transfer fluid circulating in the piping of the central solar receiver. The solar central receiver is the most crucial part in solar tower power plants. In this study, a Computational Fluid Dynamics (CFD) framework was developed for analyzing four designs of the central tower receiver, namely, a conventional uniform tube diameter solar receiver (UTD), vertical variable tube diameter solar receiver (VTD), a circular solar variable tube diameter (CVTD) receiver and a leaf type circular solar receiver (LTSR). This analysis studied the solar radiation heat transfer efficiency, temperature distribution, and fluid outlet temperature; pressure and velocity distributions for the designs using CFD. It was found that the CVTD design helped achieve a higher rise in temperature of the heat transfer fluid (HTF) when the mass flow rate was in the range of 0.1 to 0.2 liter per minute. The CVTD and LSTR models of receiver were more efficient heat transfer receiver designs compared with other designs for same surface area and strength of beam radiations.
Anti-Naturalistic Arguments From Reason
Authors: Oppy Graham
Published: March 2022

This paper discusses a wide range of anti-naturalistic argument from reason due to Balfour, Haldane, Joad, Lewis, Taylor, Moreland, Plantinga, Reppert, and Hasker. I argue that none of these arguments poses a serious challenge to naturalists who are identity theorists. Further, I argue that some of these arguments do not even pose prima facie plausible challenges to naturalism. In the concluding part of my discussion, I draw attention to some distinctive differences between Hasker’s anti-naturalistic arguments and the other anti-naturalistic arguments mentioned above.
Divine Causation and Analogy
Authors: Helm Paul
Published: March 2022

Quentin Smith’s idea is that God being the originating cause of the universe is logically inconsistent with all extant definitions of causation, and thus  logically impossible. Thus, for example  the  God of the Philosophers couldn’t have created the Universe, not  even in both its senses, in both literal and analogical senses. The thesis is advanced by accounts of the usual views of “cause”. It is maintained these is successful. Such I shall then offer an account of divine causation of my own, and thus attempt to argue that Smith has not shown that the relation that God has to the universe is not a causal relation. Such as a Humean or that of  David Lewis sense and of the “singularist” view of C. J. Ducasse would fail the analogical. And Malebranche’s “occasionalism” is surely an exception. If we turn to the other kind then  it seems to be a case of “if the data are analogical-in, then the data will be that too”. Finally, it is argued that it is more productive to consider particular individual theistic powers and perfections, for these are mongrels which literality and of analogy are compounded.