bluuebunny/crossref_metadata_2025 huggingface dataset:
Kenotic Gestures
Authors: Voss Roberts Michelle
Published: October 2020

Christians sometimes take Christ's ken?sis, or self-emptying, as the pattern for Christian love of God and neighbor. Feminist critics suspect that this model reinforces unhealthy gender norms and oppressive power structures and contest the nature and extent of this template. Interreligious study can shed light on the debate. The Gau??ya Vai??ava tradition employs the categories of Indian aesthetic theory to explain how types of loving devotion (bhakti rasa) toward Krishna are evoked and expressed. The subordinate and peaceful modes of love for Krishna can serve as a heuristic for understanding Sarah Coakley's and Cynthia Bourgeault's retrievals of ken?sis in spiritual practice. A comparative reading suggests that objections to Coakley's version, which resembles the subordinate love of God, are more intractable due to the rootedness of its aesthetic in oppressive human experiences, while Bourgeault's reclamation of ken?sis aligns with a peaceful or meditative mode of love that feminists may more readily appreciate.
Body Parts: A Theological Anthropology, by Michelle Voss Roberts. Fortress Press, 2017
Authors: Sydnor Jon Paul
Published: October 2020

Body Parts: A Theological Anthropology, by Michelle Voss Roberts. Fortress Press, 2017. 228 pp. Pb., $29 USD. 978-1-5064-1856-8
Tabula Gratulorum
Authors: Hintersteiner Norbert
Published: October 2020

Tabula Gratulorum of the Schreiter “Schülerkreis“ honoring Schreiter's contribution to Intercultural Theology.
Catholic Theological Union
Authors: Bevans Stephen Bennett
Published: October 2020

Robert J. Schreiter is one of today's most important and influential theologians. This essay suggests that the key to Schreiter's thought is his identity and spirituality as a Missionary of the Precious Blood. It is this identity and spirituality that moves him to do theology in the context of today's globalized and polarized world, offering reflections on the possibility of reconciliation and peacemaking as effective ways of engaging in mission today. The theology that results from such reflections is grounded not only in theological method, but also in the content and method of social philosophy and the social sciences.
Mining for Christ
Authors: Pranger Jan Hendrik
Published: October 2020

This article discusses the social and ecological impacts of fracking for oil on religious communities in Western North Dakota. Attention is furthermore given to racial tensions between the settler and indigenous communities that have become pronounced within churches in relation to the repudiation of the discovery doctrine and the protests at the Standing Rock Reservation against the North Dakota Access Pipeline in the fall of 2016.
Buddhism and the Religious Other
Authors: Harris Elizabeth J.
Published: October 2020

Buddhism is sometimes characterized as having an inclusivist attitude to the religious Other. In the second decade of the twenty-first century, however, an exclusivist approach to the religious Other emerged in Sri Lanka. Using the case study of a Buddhist temple in Dambulla, this article examines the conditioning factors behind this phenomenon. It is divided into four sections. The first examines recent theoretical approaches to Buddhism and inter-religious encounter, and argues that a spectrum of Buddhist approaches to the Other has long been present in text and tradition. The second offers background information about the Dambulla temple and its leading monk, Inamuluwe Sumangala Thero. The third explores three representations of the mosque attack, those of Sumangala, the Hindus of Dambulla, and secular analysts. The fourth suggests three conditioning factors for the dominance of Sumangala’s representation and the emergence of what could be considered an uncharacteristically exclusivist Buddhist approach to the religious Other within South Asian Buddhism.
Dalai Lama and Religious Diversity
Authors: De Cea Abraham Vélez
Published: October 2020

This article challenges exclusivist interpretations of the Buddha, and proposes alternative readings of early Buddhist texts that allow for the existence of the ultimate goal of the spiritual life outside Buddhism. The article clarifies the differences between exclusivist and non-exclusivist exegesis of the Buddha and suggests that exclusivist readings of his thought are a later scholastic development in the history of Buddhism. The main thesis of the article is that the Buddha cannot be considered an exclusivist because he did not understand the Dhamma and selfenlightened beings (paccekabuddhas) in sectarian terms as being the monopoly of any school. What the Buddha excludes from being paths to the final goal of the spiritual life are specific teachings incompatible with the Dhamma and the Noble Eightfold Path. This exclusion of specific teachings rather than of entire schools entails “specific exclusivism,” which is different from holding a sectarian “exclusivist view” of all non-Buddhists traditions anywhere and at any time.
Finding the Rights Questions about Religious Diversity
Authors: Gross Rita M.
Published: October 2020

This article argues that all current theologies of religion share the presupposition that differences among religions are a problem, even a mistake, and that unity or agreement would be preferable to difference and religious diversity. But theologians of religion need to start at the other end of the puzzle, conceding from the get-go that religious diversity is here to stay, is inevitable, normal, natural, and, therefore, not the major problem or issue. The important questions are not about them, the others who are different from us, but about us. Why do we dislike diversity so much? Why does it make us so uncomfortable? Why does difference so frequently elicit the response of ranking the different options hierarchically? And, most important of all, how can we cure our own discomfort with diversity? The article also suggests that we need to practice the spiritual disciplines that help us overcome our egocentric preferences for a world in which everyone else would be just like us and can, instead, live comfortable in a world that accommodates vast differences.
Farmacología y Epidemiología de Opioides
Authors: Cardoso-Ortiz J. , López-Luna M. A. , Lor K. B. , Cuevas-Flores M. R. , Flores de la Torre J. A. , Covarrubias S. A.
Published: October 2020

Los opioides desde hace muchos años son los analgésicos más utilizados y efectivos para el tratamiento del dolor. Este trabajo da a conocer la clasificación farmacológica, usos terapéuticos, riesgos a la salud y reacciones adversas de los opioides como fármacos, planteando el paradigma del usar este tipo de fármacos para el control del dolor, sin embargo se han convertido en un problema de salud en distintos países ya que en ciertas circunstancias tienen un alto potencial de causar adicción. Además de su uso contra el dolor, los opioides son utilizados como antidiarreicos, antitusivos y para el tratamiento de diversas sintomatologías. A pesar de los efectos adversos, el mal uso y abuso de los opioides; se consideran imprescindibles en la terapia contra el dolor. Actualmente las investigaciones farmacéuticas trabajan en la búsqueda constante de nuevos fármacos con efectos menos severos y con potencia analgésica
Utilidade clínica de analisadores de ensaio D-Dímero Point-Of-Care para exclusão de tromboembolismo pulmonar em pacientes com COVID-19
Authors: Silva Roberto , Souza Isabelle , Peregrino Antônio , Pessanha Cássio , Meireles Isabella , Silva Carlos
Published: October 2020

Introdução: O tromboembolismo pulmonar agudo é uma doença potencialmente fatal e a prevalência  entre os pacientes infectados pelo COVID-19 tem aumentado a demandando por exames laboratoriais e de imagem, nem sempre prontamente disponíveis. Os níveis de D-Dímeros podem ser particularmente úteis para exclusão diagnóstica. Objetivo: Avaliar a utilidade clínica de analisadores de ensaio D-Dímero POC para afastar o diagnóstico de TEP em pacientes adultos com diagnóstico de COVID-19. Método: Revisão sistemática e meta-análise. A tecnologia avaliada foi o analisador de ensaio D-Dímero Point-Of-Care. Para a combinar as estimativas de efeito cuja medida foi a diferença entre as média, utilizou-se o modelo de efeito randômico. Resultados: Foram incluídos 10 estudos que avaliaram 14 analisadores Point-Of-Care comparados ao ensaio Enzyme Linked Immunosorbent Assay. Todos os analisadores Point-Of-Care avaliados apresentaram sensibilidade e VPN superior a 95 e 97% respectivamente, com tempo de retorno do exame em média 95 minutos menor. Conclusão: As evidências sugerem que os uso de analisadores Point-Of-Care para D-Dímero tem utilidade clínica  para afastar casos de tromboembolismo pulmonar e outras complicações tromboembólicas em pacientes com COVID-19 atendidos em sala de emergência ou em unidades de atendimento de Atenção Primária.
Cyclin-Dependent Kinase 1 Activity Is a Driver of Cyst Growth in Polycystic Kidney Disease
Authors: Zhang Chao , Balbo Bruno , Ma Ming , Zhao Jun , Tian Xin , Kluger Yuval , Somlo Stefan
Published: October 2020

Significance Statement

Aberrantly upregulated cell proliferation in kidney tubule cyst cells promotes cyst progression in autosomal dominant polycystic kidney disease (ADPKD), but how mutations in polycystin genes increase cell proliferation is poorly understood. Unbiased transcriptional profiling in mouse models identified early changes in gene expression following inactivation of polycystins. Cell proliferation was the most upregulated pathway, with cyclin-dependent kinase 1 (Cdk1) a central component. Mouse models with inactivated polycystic kidney disease 1 (Pkd1) alone or with Cdk1 revealed that loss of Cdk1 significantly slowed kidney cyst growth by blocking the increased cell proliferation that follows inactivation of Pkd1. Cdk1, therefore, is a critical driver of cyst cell proliferation, and targeting it effectively inhibits cyst growth in ADPKD.

Background

Mutations in PKD1 and PKD2, which encode the transmembrane proteins polycystin-1 and polycystin-2, respectively, cause autosomal dominant polycystic kidney disease (ADPKD). Polycystins are expressed in the primary cilium, and disrupting cilia structure significantly slows ADPKD progression following inactivation of polycystins. The cellular mechanisms of polycystin- and cilia-dependent cyst progression in ADPKD remain incompletely understood.

Methods

Unbiased transcriptional profiling in an adult-onset Pkd2 mouse model before cysts formed revealed significant differentially expressed genes (DEGs) in Pkd2 single-knockout kidneys, which were used to identify candidate pathways dysregulated in kidneys destined to form cysts. In vivo studies validated the role of the candidate pathway in the progression of ADPKD. Wild-type and Pkd2/Ift88 double-knockout mice that are protected from cyst growth served as controls.

Results

The RNASeq data identified cell proliferation as the most dysregulated pathway, with 15 of 241 DEGs related to cell cycle functions. Cdk1 appeared as a central component in this analysis. Cdk1 expression was similarly dysregulated in Pkd1 models of ADPKD, and conditional inactivation of Cdk1 with Pkd1 markedly improved the cystic phenotype and kidney function compared with inactivation of Pkd1 alone. The Pkd1/Cdk1 double knockout blocked cyst cell proliferation that otherwise accompanied Pkd1 inactivation alone.

Conclusions

Dysregulation of Cdk1 is an early driver of cyst cell proliferation in ADPKD due to Pkd1 inactivation. Selective targeting of cyst cell proliferation is an effective means of slowing ADPKD progression caused by inactivation of Pkd1.
Murine Epsins Play an Integral Role in Podocyte Function
Authors: Wang Ying , Pedigo Christopher E. , Inoue Kazunori , Tian Xuefei , Cross Elizabeth , Ebenezer Karen , Li Wei , Wang Zhen , Shin Jee Won , Schwartze Eike , Groener Marwin , Ishibe Shuta
Published: October 2020

Significance Statement

When podocytes are injured, foot processes efface and detach, leading to severe proteinuria. Endocytic trafficking maintains the integrity of this crucial glomerular interface. Epsins, a family of membrane proteins, assist in the endocytosis and also take part in cell signaling. Mice that have lost podocyte-associated epsins develop proteinuria and kidney failure, due to diminished activity of the transcription factor serum response factor (SRF), which reduces cell division control protein 42 homolog activation andβ1integrin expression. Podocyte-specificSrfknockout mice also demonstrate proteinuria and kidney failure. These findings suggest that, in podocytes, epsins are required to coordinate a proper signaling platform, beyond their known endocytic properties.

Background

Epsins, a family of evolutionarily conserved membrane proteins, play an essential role in endocytosis and signaling in podocytes.

Methods

Podocyte-specificEpn1,Epn2,Epn3triple-knockout mice were generated to examine downstream regulation of serum response factor (SRF) by cell division control protein 42 homolog (Cdc42).

Results

Podocyte-specific loss of epsins resulted in increased albuminuria and foot process effacement. Primary podocytes isolated from these knockout mice exhibited abnormalities in cell adhesion and spreading, which may be attributed to reduced activation of cell division control protein Cdc42 and SRF, resulting in diminishedβ1integrin expression. In addition, podocyte-specific loss ofSrfresulted in severe albuminuria and foot process effacement, and defects in cell adhesion and spreading, along with decreasedβ1integrin expression.

Conclusions

Epsins play an indispensable role in maintaining properly functioning podocytes through the regulation of Cdc42 and SRF-dependentβ1integrin expression.
INFORMATION PROCESSING IN THE REACTOR PROTECTION SYSTEMS OF HIGH TEMPERATURE GAS-COOLED REACTORS
Authors: Suryono Tulis Jojok , Sudarno Sudarno , Santoso Sigit
Published: October 2020

Reactor protection systems (RPS) transform process variable signals from the sensors into initiation and actuation signals to trip the reactor if the signal's value exceeds the predefined trip setpoints of the RPS. Information on the current value of the process variables signals and the trip setpoint should be displayed properly on the visual display unit (VDU) in order to maintain the situation awareness of the operators in main control rooms (MCR). In addition, it is also helpful for them to investigate the cause of an accident after the reactor trip and to mitigate the accident based on the appropriate emergency operating procedures. This paper investigates how the information is processed in the RPS of Experimental Power Reactor (EPR) based on high temperature reactor (HTR) technology, and how the information is displayed on the human machine interface (HMI) of the MCR of the EPR. It is conducted by classifying the RPS into three layers based on its components and their functions, followed by the investigation of the type and the information processing in each layer. The results show that the form of the information has been changed throughout the RPS, started from the sensors and until it is displayed on the VDU. The results of the investigation are necessary to understand the concept of RPS, especially for new operators, and to prepare the mitigation actions based on the process variable that cause the reactor trip.Keywords: Experimental power reactor, Reactor protection system, Human machine interface, Information processing, Situation awareness
The Definition of Money Grand Received as a Key Determinant of Venture Investment Size in IT Russian Based Startups
Authors: Rodionov Ivan , Semenov Alexander , Oskin Aleksey
Published: October 2020

Since 2006, Russian policymakers have been actively taking various measures to stimulate the venture capital market. Government venture capital funds are being created, for example, the Russian Venture Company with a capital of 15 billion rubles. Since 2011, thanks to the new legal mechanism, state-owned companies begin to invest in private venture funds. These measures have led to increased fundraising for startups. The main mechanism of such financing is grant support for young companies. According to 2018, the amount of grants to the total amount of funds raised in Russia is one of the highest among developed and developing countries, for comparison in the USA, it is more than 2.5 times lower. The venture market specifics is such that when deciding whether to invest in a company, investors inevitably turn their attention to the previous rounds of financing the company. The purpose of the work is to analyze the effect of the money grant received on the volumes of attracting subsequent financing.

To analyze the impact of the receiving money grant, the determinant approach was used, as the most common in research on this topic. Based on a sample of 184 Russian IT startups, two OLS models have built to show the effect of money grant size to follow-on investment rounds.

As a result, various sets of determinants were considered that explain the volume of investments attracted by startups for both international markets and the Russian market. In addition, an excursus was conducted to study the effectiveness of government venture funds, which are the main grantors in the Russian venture market. Based on the results of previous studies on this topic, it was shown that the size of the money grant has a positive effect on the amount of funding attracted in both follow-on rounds. For comparison, a number of previous studies of the Russian venture capital market show that the investment size of the current round has influenced only by the previous fundraising. Such a result testifies to the attractiveness for investors Russian IT startups that received grant support.

The scientific novelty of the article is that the amount of funding attracted by startups is explained by such a specific indicator as grant support. In addition, the results obtained have certain practical value for those who invest in Russian startups. Investing in startups that received grants increases the likelihood of an exit for the investor in the next investment round.
Gene Regulatory Network v1
Authors: R Mohamed Amin , Reverter Antonio , Kijas James
Published: October 2020

Gene regulatory networks (GRNs) provide a platform for integrating multiomic data and can be used to characterize the dynamics of perturbations during biological transitions such as puberty and other complex traits. We used a multiomics approach, which has the power to identify the control mechanisms underpinning complex traits (Argelaguet et al 2019; Lloyd-Price et al 2019). We also utilised a Systems Biology approach to co-analyse genes with evidence of differential behaviour using seven categories that included expression (DEGs), changed methylation at gene bodies (DMGs) or promotors (DMPs) and differential chromatin accessibility (DACs) into gene network. To focus the analysis towards investigation of key regulators, we also performed regulatory impact factor (RIF) analysis (Reverter et al 2010). This used co-expression correlation between TFs and their target differentially expressed genes to identify master regulator TFs. For gene network inference, genes were used as nodes and significant connections (edges) between them were identified using the Partial Correlation and Information Theory (PCIT) algorithm (Reverter & Chan 2008) considering all samples. PCIT determinates the significance of the correlation between two nodes after accounting for all the other nodes in the network. Connections between gene nodes were accepted when the partial correlation was greater than two standard deviations from the mean (P < 0.05). The output of PCIT was visualized using Cytoscape Version 3.7.2 (Shannon et al 2003). Key regulators are likely to undergo substantial change in their number of connections and identify gene networks driving the transition to maturation. This prompted construction of separate networks for each physiological stage, before identifying those genes that underwent the largest change in connectivity of differentially connected genes (DCGs). References: Argelaguet, R. et al. Multi-omics profiling of mouse gastrulation at single-cell resolution. Nature https://doi.org/10.1038/s41586-019-1825-8 (2019) Lloyd-Price, J. et al. Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases.Nature 569,655–662 (2019) Reverter, A. & Chan, E.K.F. Combining partial correlation and an information theory approach to the reversed engineering of gene co-expression networks.Bioinformatics 24,2491–2497 (2008). Reverter, A., Hudson, N. J., Nagaraj, S. H., Perez-Enciso, M. & Dalrymple, B. P. Regulatory impact factors: unraveling the transcriptional regulation of complex traits from expression data. Bioinformatics 26,896–904 (2010). Shannon, P. et al. Cytoscape: a software environment for integrated models of biomolecular interaction networks. Genome Res.13, 2498–2504 (2003)
Issues of victim behavior of citizens as an object of researches conducted by scientific collectives of border states
Authors: Kharmaev Yuriy V. , Vasilyeva Zhanna A.
Published: October 2020

In this article, the authors of the study determine the current problems of victimization of citizens of border states (Russia and Mongolia). This problem is relevant due to the fact that since 2014 a visa regime was lifted between two neighboring states, which predetermined an increased flow of tourists in both directions. In order to determine the factors of victimization of foreign citizens in the host country, the author used both general scientific and special methods of cognition, including comparative legal, statistical, systemic, documentary, etc. As a result of a study of special literature, statistical data of law enforcement agencies, materials of criminal cases, certain conclusions were drawn, the main directions of criminal attacks against foreign citizens were established, and preventive measures were identified on the nature of preventing or reducing such cases and minimizing criminal consequences in relation to foreign citizens in the territory of the Russian Federation.
Optical method for fuel atomization control using high-speed video
Authors: Eskov Alexander V. , Kiryushin Ivan I.
Published: October 2020

The article discusses the description of one of the optical methods for determining the parameters of fuel atomization in atmospheric conditions and recording the results using a high-speed video camera. The possibility of interpreting images of a fuel jet in development over time as the distribution of the concentration of a dispersed medium with a constant volume-surface diameter (Sauter), which is an optical method for controlling fuel atomization, is shown.
Mechanism of structural formation in the combustion wave of the Ni-Al system with strengthening additives
Authors: Cui Hong Zhi , Grigoryevskaya Angelica A. , Gulyaev Igor P.
Published: October 2020

In the work, microstructures formed in the combustion wave of the Ni-Al system with hardening additives of high-temperature ceramic particles consisting of titanium diboride and corundum were studied. Microstructures and shapes vary depending on the content of ceramic additives in the NiAl matrix. Particles of TiB2 take the most diverse elementary forms, such as bars, plates, herringbones, regular cubic structures and cuboids. These results outline a real-time strategy of self-assembly processes to create diversified microstructures. Some grains of titanium diboride 2-5 m in size are embedded in corundum clusters, and a small number of TiB2 particles are dispersed in the NiAl matrix. It is assumed that the higher the content of reinforcing additives, the more uniform the distribution of the ceramic skeleton will be present in the NiAl matrix.
Synthesis and properties of halogen-containing macrocyclic anthraquinone imines – chemosensors for metal cations
Authors: Kudrevatykh Alexandra A. , Klimenko Lyubov S.
Published: October 2020

New crown-containing imines of 1-hydroxyanthraquinone with chlorine and fluorine atoms in the anthraquinone nucleus were synthesized. For the first time, the thermal and photochemical stages of synthesis are carried out in the solid state (without a solvent). The features of complexation of new chemosensors with cations of alkaline and alkaline earth metals were studied by spectrophotometry. It is shown that the introduction of halogen atoms in the anthraquinone nucleus leads to a significant spectral response. The obtained compounds are tested as components of test systems for visual determining the presence of alkaline earth metal cations in aqueous media.
Actual issues of calculating the term of imprisonment when set off the time of detention and house arrest
Authors: Avdeeva Ekaterina V.
Published: October 2020

The subject of the study is to consider the issues regarding the set-off of the time spent in custody or house arrest at the time of punishment, both during the sentencing and during its execution.

The purpose of the study is to disclose the problematic issues of calculating the period of detention subject to offsetting the term of imprisonment, the beginning of the term of serving a sentence of imprisonment. The procedure for setting off the time spent by a person under house arrest until a court verdict comes into force is considered if a court imposes a sentence that is not related to isolation from society.

The main results of the study reflect problems in sentencing if the time of detention absorbs the sentence assigned to the defendant by the court, as well as the issues of applying preferential rules for setting off the time of detention in custody when sentencing for the totality of crimes and the totality of sentences, criminal of the law in time when the time in the sentence is set off, for crimes committed before July 14, 2018.

As a fundamental direction, the scientific and practical validity of the criminal law policy and legislative processes, the optimization of the implementation of the criminal law are noted.
MESSAGE ACCEPTANCE OF NGAJI FILSAFAT PREACHING THROUGH INSTAGRAM
Authors: Prakoso Bayujati
Published: October 2020

This study aimed to understand the impact of message acceptance of Ngaji Filsafat preaching through Instagram using the Albert Bandura Social Learning Theory. In achieving the goal, this study used a qualitative approach with the case study method. Data sources of this study were from interviews on 13 informants and documentation. The study result shows that Ngaji Filsafat preaching through Instagram is effective in motivating hijra for the better, such as improving religiosity understanding, providing life values motivation, motivating to continue to improve and reflect oneself, improving knowledge insight, and triggering oneself to create change movements. These behaviors are inherent with environmental factors, knowledge (personal), and informants’ behavior. It is consistent with Albert Bandura’s triadic reciprocal.
ONLINE REPUTATION CONCEPTUALIZATION
Authors: Sugiono Shiddiq
Published: October 2020

The development of information and communication technology is considered to have expanded the concept of reputation in the online realm. This expansion has an urgency for further investigation because in this case the internet has become the main medium used to find various sources of information. The purpose of this study is to further conceptualize online reputation and map the variables that become the impact of this concept based on studies from various academic literature. This article is a literature study using systematic literature review techniques through a qualitative approach. Basically, online reputation is rooted in the concept of word of mouth, this is consistent with the organizational reputation management model that has been formulated previously. The availability of various information on the internet becomes a source for someone to determine the reputation of an object. Online reputation must be followed by management efforts so that the expected results of the online activity strategy can be obtained. The variables that are the impact of online reputation management include: verification of asymmetric information, building personal and product brands, building brand loyalty, building trust in conducting online transactions.
THE INTERPRETATION AND ATTITUDE OF BODY SHAMING BEHAVIOR ON SOCIAL MEDIA (A DIGITAL ETHNOGRAPHY STUDY ON INSTAGRAM)
Authors: Fitria Kusnul , Febrianti Yessi
Published: October 2020

The main objective of this research is to reveal the meaning and attitudes of victims of body shaming behavior on social media. Body shaming is the behavior of giving negative comments about a person's physical condition. Instagram is the social media most often used by body-shaming actors to carry out their actions. This research is a digital ethnographic study with primary data collection through digital observation, and in-depth interviews with five informants who were selected purposively. The results of this study, in general, encompass the description of three things which are: a) the awareness and experiences of the victim; b) the attitude of the victim; and c) the two ways interactions between the victim and the followers. The interpretation of the body shamming victims reflects body positivity and self-love form of content on their personal Instagram.
Isolation of non-fermenting Gram negative bacteria in respiratory tract infections
Authors: Sharma Shweta , Pujari Sujata , Kumar Sharma Amit
Published: October 2020

Respiratory tract infections are the most common diseases that are associated with mortality and morbidity. They are often misdiagnosed due to its nonspecific presentation in clinical settings. The risk factors of RTI vary geographically and timely(1). So it is important to evaluate more for RTI causative agents.

The non-fermentative Gram negative bacilli (NFGNB) are often associated with RTI. The NFGNB are a group of several different aerobic, non-sporing, Gram negative bacilli that either unable to utilize carbohydrates as a source of energy or withhold them through metabolic pathways other than the fermentation.

The study was undertaken to identify various non- fermenters by additional conventional tests, isolated from patients having respiratory tract infection in department of Microbiology, SVPPGIP and SCBMCH Medical college, a Tertiary Care Center, Odisha. Our study also line up the singnificant role of NFGNB as respiratory pathogens.

391 (14.6 %) non-fermenters were isolated from 2678 clinical specimens. Out of which NFGNB(391 samples), a total of 143 (36.57%) were from various respiratory samples were included in this study and were isolated on MacConkey and blood agar plates incubated at 35°C for 24-48 hours.

Patients mostly belonged to age group of 65 to 80 years and were 96(67%)male. complex 67(46.8%) was the commonest isolate followed by 56(39.1%).

While other NFGNB like were isolated in few respiratory samples.

The most effective antibiotics were Tigecycline and Polymyxin B/ Colistin, however majority of them showed multidrug resistance.
Dental setup in the covid-ified era – A review
Authors: Asok Nikhil , Srivastava Vipul , Tandon Ragni , Mahajan Shally , Sonal
Published: October 2020

The infectious agent of this viral pneumonia happening in Wuhan was finally identified as a novel coronavirus (2019-nCOV), the 7 member of the family of coronaviruses that infect humans widely known as Covid-19. The common transmission routes of novel coronavirus include direct transmission like cough, sneeze, and droplet inhalation transmission and contact transmission contact with oral, nasal, and eye mucous membranes. Live viruses (COVID-19) were isolated from the saliva. Hence, healthcare workers particularly the dental professionals are at more risk.

An overview of how-to setup the dental office so as to minimize the risk of transmission while simultaneously carrying out the necessary treatment procedures.

A proper management and setup of the dental office and treatment planning along with strict categorisation of patients is necessary for a successful and safe practice during Covid times.
Unusual extraction combinations in orthodontics – A literature review
Authors: Shetty Shresha , Kumar Anil
Published: October 2020

Extractions in orthodontics has been an important area of consideration as it is one of the most important factors, responsible for the success of treatment. Conventionally, the premolar extractions are the most followed. But as years passed by, finishing of the case has been given utmost importance. A proper extraction decision is the key for a good case finish. In other words, traditional extraction considerations needs to be reconsidered to satisfy the patient needs. This paper provides a review of unusual extraction combinations which can be considered at various clinical situations.
Osseoperception in osseointegrated implants - A review
Authors: Parameswari B Devi , Ranjith R , Annapoorni H
Published: October 2020

Patients who are edentulous lacks the mechanoreception which is mainly provided by the periodontal ligament that attaches a tooth to the alveolar bone. Mechanoreceptors are primarily present witihin periodontal ligament which provides feedback of magnitude, direction and rate of occlusal load application for sensory perception. Tactile sensibility is seen to be developed in patients who are treated with osseointegrated dental implants. This phenomenon is named as osseoperception. The aim of this article is to evaluate the available literature to find osseoperception related to dental implants.
Memahami Kecemasan: Perspektif Psikologi Islam
Authors: Nugraha Aditya Dedy
Published: October 2020

AbstractAnxiety has always been an interesting topic, how anxiety can be the entrance to other personality disorders and how humans are able to adapt to overcome anxiety into a research theme that remains hot to study. This study examines what anxiety is, how previous research is able to overcome anxiety. This study uses two perspectives, namely psychology in general and Islamic psychology in particular Islamic Psychotherapy. This study uses the literature review method, which originated from Garuda (Digital Reference Garba) from the KemenristekBrin, to study what techniques can reduce anxiety. The results obtained that in addition to psychotherapy, Islamic psychotherapy has also begun to be used to reduce individual anxiety levels.AbstrakKecemasan selalu menjadi topik yang menarik, bagaimana kecemasan dapat menjadi pintu masuk menuju gangguan kepribadian lainnya dan bagaimana manusia mampu beradaptasi mengatasi kecemasan menjadi tema riset yang tetap hangat untuk dikaji. Penelitian ini mengkaji apa itu kecemasan, bagaimana penelitian terdahulu mampu mengatasi kecemasan. Penelitian ini menggunakan dua sudut pandang, yaitu psikologi secara umum dan psikologi Islam khususnya Psikoterapi Islam. Penelitian ini menggunakan metode literature reviews, yang berasal dari Garuda (Garba Rujukan Digital) dari Kemenristek-Brin, untuk dikaji teknik apa saja yang bisa menurunkan kecemasan. Hasilnya diperoleh bahwa selain psikoterapi, psikoterapi Islam juga sudah mulai digunakan untuk menurunkan tingkat kecemasan individu.
Hydroxychloroquine-Induced Hyperpigmentation: A Case Report
Authors: Talaschian Mona , Sadeghi Anahita , Pakzad Sara
Published: October 2020

Antimalarial agents, including chloroquine and hydroxychloroquine, have been used for the treatment of various rheumatoid diseases and skin diseases because of their anti-inflammatory and immune-modulating properties. Cutaneous adverse effects such as exacerbation of psoriasis, pruritus, and hyperpigmentation have been reported as side-effects of antimalarial drugs. In this case, we report a middle-aged man with a history of rheumatoid arthritis who was treated with non-steroidal anti-inflammatory drugs and hydroxychloroquine. He complainedof hyperpigmentation of the face after one year of initiating the hydroxychloroquine. It was discontinued and methotrexate was started. Skin biopsy was confirmed drug reaction. Aftermore than 10 years of follow up, his skin discoloration had not been improved.
The Effect of Ozone Treatment on Thermal Burn Wound Healing; An Experimental Study
Authors: PEKER Kemal , YILMAZ İsmayil , DEMİRYILMAZ İsmail , ISIK Arda , SAYAR İlyas , GÜRSUL Cebrail , ÇANKAYA Murat , ÇOBAN Taha Abdulkadir
Published: October 2020

Objective: Ozone has been advised as a metabolic excitative in cell, immuno-modulatory agent and antioxidant enzyme actuator. The presentstudy was performed to designate the profit of ozone therapy on the burn wound healing in the rats.Method: 40 adult Wistar type rats divided into 4 groups: a control group (burnno created and topical and systemic agents no used), a burn group (burn created but only saline given), a burn+silver sulfadiazine group (silver sulfadiazine was applied for 21 days), a burn+ozone/oxygen mixture group (ozone/oxygen mixture was applied for 21 days).After anesthetizing, second-degree burn (2 cm2 areas) wasdoneon the dorsal of the animals byaluminum plate in boiling hot water (100 ˚C for 15 seconds) and other groups except control groupwere treated topically, based on the time scheduled. Tissue samples were harvested on day 7st and 21st after burn injury. Biochemical and histological analyzes were performed in tissue and blood samples. The results were assessed with appropriate statistical tests and givenas Means±SD. Results: The histopathologic damage level was significantly different in all groups. Fibrosis and inflamation levels decreased in ozone treatment and silver sulphadiazine groups compared to burn+normal saline group on the 21 days according to 7 days. In the ozone treatment group, Glucose 6-phosphate dehydrogenase activities were significantly higher than the silver sulfadiazine treated group. But glutathione reductase enzymeactivities were loverin the ozone treated group and hydroxyproline concentration decreased in ozonegroup compared to burn+normal saline group on 7 and 21 days. Conclusion: Ozone has a detractive effect in the development of inflamation, fibrosis, and granulation via decreasing tissue damage and increasing the antioxidant enzyme activity on burn wound healing.
Should children with sub-threshold ADHD predominantly inattentive subtype (ADHD-I) symptoms be treated with Sensory ıntegration therapy? A case-control study.
Authors: DOĞRU Hicran , DURSUN Onur Burak , ÖZTEKİN Nurşah
Published: October 2020

Objective: Sensory integration therapy is one of the promising preventive therapy options for behavioral and developmental disorders. Hypothesizing a degree of parallelism, this study provides an insight into the effectiveness of the sensory integration therapy potencies for school-aged children with subthreshold ADHD predominantly inattentive subtype.
Method: The study was a single-arm clinical trial and 20 patients aged 7–10 years with subthreshold ADHD predominantly inattentive subtype, were included. The sensory integration intervention was prepared in accordance with sensory modulation principles and intervention strategies and lasted 12 weeks with two sessions per week. The effectiveness was assessed using the Conner’s teacher/parent scales, the Clinical Global Impression scale, the Canadian Sensory integration Performance Measure and the Sensory Profile.
Results: The rate of patients with typical or better performance in auditory processing domain of the Sensory Profile was found significantly increased after sensory integration therapy; 9 patients (45%) before and 15 patients after (75%) (p=0.031). The rates of participants with typical or better performance in inattention–distractibility factor score of the Sensory Profile were found significantly increased after sensory integration therapy; 6 before (30%) and 16 after (80%) (p=0.006).
Conclusion: Sensory integration therapy focuses on supporting persons with varied disability terms to engage in daily life activities that they find significant and purposeful. Difficulties experienced by individuals with subthreshold attention-deficit hyperactivity disorder are addressed in this study and aspects of daily life are explored while swiping through different sensory modalities. Impaired auditory processing improvable through sensory integration therapy was observed in these children.
Incidental Gallbladder Cancer Diagnosed During or After Laparoscopic Cholecystectomy, What Did We Do ?
Authors: SAPMAZ Ali , GÜLDOĞAN Cem , KESKİNKILIÇ Betül , KARACA Ahmet
Published: October 2020

Objective: Gallbladder cancer is a rare neoplasm. We report our experience with gallbladder cancer that was incidentally diagnosed during or after laparoscopic cholecystectomy performed for gallstone disease.
Method: This study included all laparoscopic cholecystectomies due to gallstone disease undertaken from January 2010 to April 2015. Exclusion criteria were suspicion of malignancy and/or existence of gallbladder polyps detected with ultrasonography preoperatively. Patients with incidentally diagnosed gallbladder cancer were recorded, and the clinical and demographic characteristics of these patients were reviewed.
Results: Of 6,114 patients in whom laparoscopic cholecystectomy was attempted, 5,948 were included in this study. Incidental gallbladder cancer was found in thirty-six patients, with a mean age of 64.08 years. The histological tumor stages were adenocarcinoma in situ in seven patient, pT1b in nine patient, pT2 in eleven patient, and pT3 in nine patients. Sixteen patients who underwent laparoscopic cholecystectomy alone underwent no additional surgery because of the low stage of the tumors. The twenty remaining patients, whose laparoscopic cholecystectomies were converted to open surgeries, underwent cholecystectomy, excision of the liver bed and lymph node dissection. The overall median survival time was 28 months.
Conclusion: The incidence of incidental gallbladder cancer has been reported to vary, up to 2.85%. In this single-center study, the rate of incidental gallbladder cancer was found to be 0.60%. Female gender and advanced age are demographic risk factors for gallbladder carcinoma. Although gallbladder cancer is well known for its poor prognosis, tumors that are incidentally diagnosed are often found at an early stage and have a better prognosis.
On the Construction of Biobank in General Hospitals
Authors: Yu Meng , Du Chen , Yan Qingyu , Zhang Chi , Wu Feixiang , Zhou Cheng
Published: October 2020

Objective: discussion on a series of biospecimen related issues are conducted, such as collection and preservation, quality control, as well as management and application, during the construction of human tissue biobank in a general hospital. Methods: To develop a set of standardized operational procedures and to collect tissue samples, such as whole blood, serum, plasma, fresh frozen tissues, cerebrospinal fluid, and paraffin-embedded tissues, which were classified and made aliquots according to different requirements, and stored at -80℃ temperature refrigerator or in liquid nitrogen. At the same time, a set of information management software was used to realize management of the biobank. Results: currently, there are more than 20,000 specimens of various benign and malignant cases, which cover 380 diseases, being collected in the biological database in our hospital. These specimens include paraffin-embedded tissue, fresh frozen tissue, femoral head, whole blood, plasma, serum and cerebrospinal fluid, etc. A large number of these specimensare beneficial is used in clinical research at present. Conclusion: the establishment of biological sample bank can maximize the value of non-reborn human tissue specimens, and provide normal control standards as well as benign and malignant disease standards for clinical diagnosis and treatment, which is of great significance to the research of disease pathogenesis and the development of detection technology.
O CURSO DA EPIDEMIA: a Fundação Rockefeller e os surtos de febre amarela na Bahia em 1926
Authors: BATISTA RICARDO DOS SANTOS , SOUZA CHRISTIANE MARIA CRUZ DE
Published: October 2020

Este texto tem como objetivo analisar ações de controle da febre amarela na Bahia, especialmente durante o surto de 1926, que contribuiu para questionar a eficácia da teoria dos “focos-chave”, defendida pela Fundação Rockefeller. Membros da agência filantrópica internacional e médicos baianos atuaram para tentar encontrar o centro difusor da epidemia. Utilizam-se como fontes relatórios, correspondências e fotografias coletados no Rockefeller Archive Center, um relatório do Serviço de Profilaxia Rural da Febre Amarela, artigos escritos por médicos em periódicos especializados e notícias publicadas em jornais da época. Inquéritos epidemiológicos e clínicos foram instaurados, enquanto a doença se proliferava ao longo da linha do trem, que atravessava o estado.
Palavras-chave: Febre Amarela. Teoria Dos Focos-Chave. Saúde Internacional.
Notas sobre la tenencia de la tierra entre los mayas de la antigüedad
Authors: Villa Rojas Alfonso
Published: October 2020

Los pocos datos que sobre la tenencia de la tierra aportaron los primeros cronistas e historiadores de Yucatán, revelan que el tema no fue de su especial interés. Esta deficiencia contrasta con la abundancia de información que se tiene sobre las normas de derecho agrario entre los antiguos tlenochcas y tlaltelolcas del antiplano mexicano, según se puede ver al revisar el famoso estudio de Bandelier sobre este aspecto de su organización social. Para los Mayas de Yucatán la situacion es muy distinta, pues, los autores clásicos que tratan de ellos, tales como Diego de Landa y López de Cogolludo, apenas dedican al tema unas cuantas líneas, y ello en forma superficial y un tanto ambigua.
Excavaciones en un cementerio de Palenque
Authors: Rands Barbara C. , Rands Robert L.
Published: October 2020

Doctor en Filosofía de la Universidad de Columbia, especializado en arqueología mesoamericana. Profesor de antropología de la Universidad de Mississippi; Investigador del Museo de la Universidad de Pennsylvania. Trabaja con la cerámica de Palenque y Piedras Negras. Obras principales: The Water Lily in Mayan Art: A complex of Alleged Asiatic Origin, Some Manifestations of Water in Mesoarnerican Art, Elaboration and Invention in Ceramic Traditions.
Las Estelas 4 y 5 de Balancán-Morales, Tabasco
Authors: Lizardi Ramos César
Published: October 2020

La descripción y la lectura parcial de las Estelas 4 y 5 de Balancán-Morales, Tabasco, que se dan en seguida, son producto de los viajes hechos por el autor a los Municipios de Balancán y Tenosique, de ese estado, en noviembre de 1959 por cuenta de la Dirección de Monumentos Prehispánicos, del Instituto Nacional de Antropología e Historia; en junio de 1960 por cuenta de un Diario de esta capital y en marzo de 1961 por cuenta propia.
El tonalismo y el nagualismo entre los tzotziles
Authors: Holland William R.
Published: October 2020

En varias ocasiones los mesoamericanistas han prestado su atención al difícil problema de distinguir entre el tolanismo y el nagualismo. Hasta la fecha las formulaciones más aceptadas son las de Foster (1944:85-105) y Kaplan (1956:363-68), que se citarán más adelante. el presente autor es de opinión que no se han estudiado estos conceptos en la vida actual lo suficiente para comprenderlos ni su importancia en la vida prehispánica. El problema se resuelve escogiendo un grupo indigena cuya vida es, en la medida en que sea posible, de tipo prehispánico.
Contrata de un maya de Yucatán, escrita en su lengua materna, para servir en Cuba, en 1849
Authors: Barrera Vázquez Alfredo
Published: October 2020

El documento que nos ocupa fue hallado en Mérida por quien esto escribe, entre otros papaeles viejos que adquirió, en 1940, de un comerciante de antigüedades. Consta de tres piezas de papel delgado del comúnmente usado a mediados del siglo XIX para correspondencia, de 25.4 X 16.1 centímetros, aparentemente medias hojas cortadas con plegadera, escritas en amabas caras, con pluma de ave o cálamo, con tinta muy diluída de color café actualmente, excepto algunas anotaciones marginales, posteriormente escritas con la misma técnica y tinta igualmente diluída, pero de color menos amarillento y más negruzco.