bluuebunny/crossref_metadata_2025 huggingface dataset:
The effects of infectious dosages on endogenous phage and the excretion of Eimeria tenella oocysts of infected chicken
Authors:   Faculty of Animal Science and Veterinary Medicine, University of Agriculture and Forestry, Hue University, Hue City 530000, Vietnam, Dung Ho Thi , Nguyen Thi Hoa ,   Faculty of Animal Science and Veterinary Medicine, University of Agriculture and Forestry, Hue University, Hue City 530000, Vietnam, Nguyen Thi Thuy ,   Faculty of Animal Science and Veterinary Medicine, University of Agriculture and Forestry, Hue University, Hue City 530000, Vietnam., Phung Le Dinh ,   Faculty of Animal Science and Veterinary Medicine, University of Agriculture and Forestry, Hue University, Hue City 530000, Vietnam., Hung Pham Hoang Son ,   Faculty of Animal Science and Veterinary Medicine, University of Agriculture and Forestry, Hue University, Hue City 530000, Vietnam
Published: April 2024

This study was conducted to evaluate the effects of four dosages of oocyst inoculation (1×102, 1×103, 1×104, and 1×105 oocysts/chick) on oocyst patterns in feces, lesion score, and the endogenous phase of Eimeria tenella in the tissue of infected chickens. Oocysts in feces were collected daily from 4 to 10 day-post-infection (dpi). Chickens were killed at 0, 3, 5, and 10 dpi to evaluate the lesion score and the endogenous phage in the tissue by hematoxylin and eosin staining. The results showed that chickens in the highest dosage group discharged oocysts the earliest (5 dpi), while oocysts were detected in the other 3 groups 1 day later (6 dpi). The results of the histopathological examination showed that the time to detect the development stages of E. tenella in the tissue was similar among the experimental groups. Specifically, the asexual stages (1st and 2nd schizonts) were detected at 3 dpi, and immature oocysts were found in the cecum tissue at 5 dpi in all experimental groups. Overall, the results indicated that the oocyst dosages do not affect the replication of E. tenella in intestinal epithelial cells but may influence the excretion of oocysts from the intestinal tissue.
Extended-spectrum beta-lactamase (ESBL) production and virulence genes profile of avian pathogenic Escherichia coli (APEC) isolated from broiler chickens in eastern Thailand
Authors:   Faculty of Veterinary Medicine, Rajamangala University of Technology Tawan-ok, Chonburi, 20110 Thailand, Tongkamsai Suttitas , Nakbubpa Kulchai ,   Faculty of Veterinary Medicine, Rajamangala University of Technology Tawan-ok, Chonburi, 20110 Thailand
Published: April 2024

Avian pathogenic Escherichia coli (APEC) causes colibacillosis, resulting in extensive economic losses for the broiler industry. To date, there is little information in Thailand about virulence-associated genes and antibiotic resistance of APEC strains. Here, this study aimed to investigate the virulence genes and extended-spectrum beta-lactamase (ESBL) characteristics of APEC isolated from broilers. This study used multiplex polymerase chain reaction (PCR) to determine the presence of virulence genes and resistance genes in APEC. Furthermore, the disc diffusion method examined ESBL phenotypes of APEC and antibiotic resistance profiles against 17 antimicrobials. In this study, E. coli was isolated 11 (6.32%) of 174 broiler visceral organs. All E. coli isolates were tested for five APEC-virulence-associated genes (iroN, ompT, hlyF, iutA, and iss). Eight E. coli isolates from broilers with colibacillosis-associated lesions carried two (iroN and ompT) of the APEC virulence genes. One APEC virulence gene (hlyF) was found in E. coli isolates from broilers without lesions. Possibly no individual virulence gene was specific to the APEC strain. Interestingly, the papC, previously detected in humans with uropathogenic E. coli, was found in an APEC isolate. All APEC isolates were ESBL-producing E. coli, and then they were tested for four beta-lactamase-encoding genes (blaTEM, blaCTX-M, blaOXA, and blaSHV). The blaTEM and blaCTX-M were identified in 81.81% (9/11) of the isolates, whereas blaOXA or blaSHV were not detected in any isolate. All APEC showed multi-drug resistance (MDR) phenotypes, especially chloramphenicol, erythromycin, and sulfamethoxazole-trimethoprim. Although antibiotics were not recently used, MDR might be encouraged by horizontally transferring antibiotic-resistance genes. In addition, fluoroquinolone resistances were found in APEC isolates which could transfer resistance genes to humans via the food chain. This study indicates that APEC isolates contain several virulence and bla genes and should be surveillance to prevent the transmission of those genes to humans.
Genetic improvement approaches of indigenous cattle breeds for adaptation, conservation and sustainable utilization to changing climate in Ethiopia
Authors:   Department of Animal Sciences, College of Agriculture, food and climate sciences, Injibara University, Injibara, P,O.BOX: 40, Ethiopia, Tariku Woldeyohannes , Betsha Simret ,   School of Animal and Range Sciences, College of Agriculture, Hawassa University, Hawassa, P.O.BOX: 05, Ethiopia, Melesse Aberra ,   School of Animal and Range Sciences, College of Agriculture, Hawassa University, Hawassa, P.O.BOX: 05, Ethiopia
Published: April 2024

This paper attempts to review the cattle genetic improvement approaches for sustainable utilization, adaptation, and conservation in the face of changing climatic conditions. Livestock production is affected by climate change, which poses a greater threat to populations that rely on them for their overall food security. Climate change negatively affects cattle production directly through its impact on animal physiology, behavior, and health and indirectly through its effect on feed and water availability, quality and quantity of pasture, forage crops, and rangeland due to increased temperature droughts. Improvement of cattle genetic resources that are efficient and well adapted to extreme temperatures, low-quality diets, and disease challenges is critical to effectively cope with climate change. Designing suitable breeding strategies will facilitate improving the performance of cattle breeds and enhance their tolerance to the dynamics of climate change. Replacement of local cattle breeds with exotic ones and unplanned crossbreeding with them without enough consideration of environmental conditions are among the major factors contributing to the loss of locally adapted breeds that possess certain adaptive traits. Maintenance of indigenous cattle’s genetic diversity, which underpins resistance to environmental stresses is a viable strategy to mitigate the possible effects of future climatic challenges. In contrast to the traditional selection, genomic selection increases the accuracy of selection with the largest genetic gain, for the low heritability traits such as adaptability and longevity. In conclusion, any breeding strategies should be relevant in terms of breed suitability, performance, and adaptability in the given production environment to sustain cattle production.
Otolith morphometry and its role in determining the growth of Periophthalmus chrysospilos distributed in some coastal provinces in the Mekong Delta
Authors:   Cuu Long University, Phu Quoi Commune, Long Ho District, Vinh Long Province 890000, Vietnam, Lam Tran Thi Huyen , Dinh Quang Minh ,   Department of Biology, School of Education, Can Tho University, Xuan Khanh ward, Ninh Kieu district, Can Tho 900000, Vietnam, Nguyen Ton Huu Duc ,   Department of Biology, School of Education, Can Tho University, Xuan Khanh ward, Ninh Kieu district, Can Tho 900000, Vietnam
Published: April 2024

This article first provided information on otolith shapes, the variation of otolith weight by sex, fish size, season, and sampling site, and the linear relationship between otolith weight and fish size. A total of 815 Periophthalmus chrysospilos specimens from Duyen Hai, Tra Vinh; Tran De, Soc Trang; Dong Hai, Bac Lieu; and Dam Doi, Ca Mau in the Mekong Delta ranged from 4.20 to 12.50 cm total length and from 1.26 to 16.88 g weight were analysed. The analysis results revealed that Ps. chrysospilos had a square otolith, deeply notched at the anterior apex and flat at the posterior apex. The weight of the left otolith showed a statistical difference according to survey factors, including gender, fish size, season, and sampling site. The otolith weight had a proportional relationship with to the total length, body weight, and head length of mudskippers (r2 =0.7~0.9), which meant that fish size could be predicted from the otolith weight and about 70-90% of the otolith weight of Ps. chrysospilos varied corresponded the growth of the fish.
Unravelling key genes associated with ovine Brucellosis by differential gene expression analysis: A holistic bioinformatics study
Authors:   ICAR-National Institute of Veterinary Epidemiology and Disease Informatics (NIVEDI), Yelahanka, Bengaluru-560064, India, Ramesh Varsha , Indrabalan Uma Bharathi ,   ICAR-National Institute of Veterinary Epidemiology and Disease Informatics (NIVEDI), Yelahanka, Bengaluru-560064, India, Rani Swati ,   ICAR-National Institute of Veterinary Epidemiology and Disease Informatics (NIVEDI), Yelahanka, Bengaluru-560064, India, Suresh Kuralayanapalya Puttahonnappa ,   ICAR-National Institute of Veterinary Epidemiology and Disease Informatics (NIVEDI), Yelahanka, Bengaluru-560064, India, Barman Nagendra Nath ,   Assam Agricultural University, Khanapara, Guwahati, Assam-781022, India, Palavesam Azhahianambi ,   Tamil Nadu Veterinary and Animal Sciences University, Chennai, Tamil Nadu-600051, India
Published: April 2024

Ovine Brucellosis, caused by Brucella ovis bacteria, is a pathognomonic reproductive infectious disease of sheep that causes epididymitis in rams (male sheep) and placental inflammation in ewes (female sheep) leading to reduced fertility. The specific molecular process that causes alterations in genome of sheep during brucellosis is not yet fully understood. This study aimed to identify key host genes associated with the pathogenesis of ovine brucellosis caused by B. ovis. The GSE35614 dataset containing six healthy and six Brucella ovis infected sample of rams in the chronic phase 2 was obtained from the NCBI GEO database to examine and detect any differences in gene expression (DEGs). Functional and pathway enrichment analyse of the DEGs were performed along with the construction of protein-protein interaction network. Next, functional modules and hub genes were clustered and identified respectively, using the MCODE plugin. As a result, a total of 316 differentially expresses genes were filtered according to the provided cut-off criteria. The enriched DEGs were related to extracellular matrix interaction, cell adhesion mediated by integrin, angiogenesis, and inflammatory response. Furthermore, the hub gene analysis resulted in five hub genes namely, FN1, FBN1, CDH1, CD44, and SPP1, were up-regulated during the infection which could lead to reproductive disorders in sheep. In conclusion, the DEGs, functional and pathways terms, along with hub genes identified in the current study can provide prospective targets for the early diagnosis and treatment of brucellosis and provide insight into the molecular mechanism underlying the alterations that occur during brucellosis in sheep.
Effect of encapsulated Medinilla javanensis fruit extract on growth, protein digestibility and health of broilers
Authors:   Department of Animal Science, Faculty of Animal and Agricultural Sciences, Universitas Diponegoro, Semarang, Central Java, Indonesia, Dityana Achmad Muzakky , Yunianto Vitus Dwi ,   Department of Animal Science, Faculty of Animal and Agricultural Sciences, Universitas Diponegoro, Semarang, Central Java, Indonesia, Krismiyanto Lilik ,   Department of Animal Science, Faculty of Animal and Agricultural Sciences, Universitas Diponegoro, Semarang, Central Java, Indonesia, Sugiharto Sugiharto ,   Department of Animal Science, Faculty of Animal and Agricultural Sciences, Universitas Diponegoro, Semarang, Central Java, Indonesia
Published: April 2024

The study investigated the effect of encapsulated Medinilla javanensis fruit extract on performance, protein digestibility, and health of broilers. A total of 200 Cobb broiler chicks were divided into five treatments with four repetitions, including T0 (basal diet), T1 (basal diet + 200 mg/kg encapsulated Medinilla javanensis fruit extract), T2 (basal diet + 400 mg/kg encapsulated Medinilla javanensis fruit extract), T3 (basal diet + 600 mg/kg encapsulated Medinilla javanensis fruit extract), and T4 (basal diet + 800 mg/kg encapsulated Medinilla javanensis fruit extract). Sample collection was conducted on day 35 of age. Results showed that increased encapsulated Medinilla javanensis fruit extract levels in feed linearly increased (P<0.05) body weight, body weight gain, intestinal lactic acid bacteria counts, protein digestibility and serum superoxide dismutase levels, while linearly decreasing (P<0.05) feed conversion ratio, intestinal Escherichia coli counts, small intestinal pH values and serum malondialdehyde levels. In conclusion, encapsulated Medinilla javanensis fruit extract improved growth performance, protein digestibility intestinal health and antioxidant status of broilers. The encapsulated Medinilla javanensis fruit extract at a level of 600 mg/kg exerted the best performance and health of broilers.
Prevalence of Campylobacter and antibiotic susceptibility in chickens at slaughterhouses and retail markets in the Mekong Delta
Authors:   Faculty of Veterinary Medicine, College of Agriculture, Can Tho University, Ninh Kieu, Can Tho 90000, Vietnam, Phong Le Hong ,   National Center for Veterinary Hygiene Inspection No.2, Tan Binh District, Ho Chi Minh City 700000, Vietnam, Tran Nguyen Phuc Bao ,   Faculty of Veterinary Medicine, College of Agriculture, Can Tho University, Ninh Kieu, Can Tho 90000, Vietnam,   National Center for Veterinary Hygiene Inspection No.2, Tan Binh District, Ho Chi Minh City 700000, Vietnam, Cuc Nguyen Thi Kim ,   National Center for Veterinary Hygiene Inspection No.2, Tan Binh District, Ho Chi Minh City 700000, Vietnam, Nguyen Thanh Lam ,   Faculty of Veterinary Medicine, College of Agriculture, Can Tho University, Ninh Kieu, Can Tho 90000, Vietnam, Nguyen Duc Hien ,   Faculty of Veterinary Medicine, College of Agriculture, Can Tho University, Ninh Kieu, Can Tho 90000, Vietnam
Published: April 2024

This study aims to determine the prevalence of Campylobacter and its antibiotic susceptibility at slaughterhouses and live poultry markets in the Mekong Delta, Vietnam. A total of 177 samples, including 112 fecal samples, 28 cecal samples, and 37 rectal swab samples were collected. Thirty-nine samples tested positive for Campylobacter spp. by culture method, accounting for 22%. Isolation rates of Campylobacter in rectal swab samples were highest at 29.7% (11/37), followed by cecal samples at 25% (7/28) and fecal dropping samples at 18.8% (21/112). Species identification was performed by multiplex PCR and the result showed that the prevalence of Campylobacter coli (12.4%) was higher than Campylobacter jejuni (3.4%). Antibiotic susceptibility test showed that all isolated Campylobacter were susceptible to imipenem and meropenem (100%). Most Campylobacter were resistant to tetracycline (96.4%), ciprofloxacin (92.9%), nalidixic acid (89.3%), and ampicillin (67.9%). This study highlights the high contamination of Campylobacter and its antibiotic resistance in poultry in the Mekong Delta, Vietnam.
The Productive and physico-chemical performance at two seasons of the year in trout (oncorhynchus mykiss)
Authors:   Departamento Académico de Zootecnia, Universidad Nacional del Centro del Perú, Junín, Huancayo 12006, Perú, Garcia Edgar , Carhuas Jordan Ninahuanca ,   Departamento Académico de Zootecnia, Universidad Nacional del Centro del Perú, Junín, Huancayo 12006, Perú, Hilario Isabel ,   Departamento Académico de Zootecnia, Universidad Nacional del Centro del Perú, Junín, Huancayo 12006, Perú, Rojas Wilmer ,   Departamento Académico de Trabajo Social, Universidad Nacional del Centro del Perú, Huancayo 12006, Av. Mariscal Castilla N° 3909, Junín, Peru, Solís Jose ,   Departamento Académico de Ingenieria en Industrias Alimentarias, Universidad Nacional del Centro del Perú, Huancayo 12006, Av. Mariscal Castilla N° 3909, Junín, Peru
Published: April 2024

The objective of the research was to evaluate the productive and physicochemical performance of trout (Oncorhynchus mykiss) in two seasons of the year. The months of April-June for the rainy season and July-September for the dry season in the Junín region of Peru were considered. The productive performance variables were: length, live weight, carcass weight and yield; on the other hand, the physicochemical variable (pH, water retention, humidity, ash, ethereal extract and protein). The results indicate that no differences (p>0.05) were found between the rainy and dry seasons for: length (cm), moisture (%), ash (%), ethereal extract (%) and protein (%). On the contrary, differences (p<0.05) were found between the rainy and dry seasons for live weight (g) with 239.37 g and 186.30 g respectively, as well as differences for carcass weight (g) in the rainy (186.30 g) and dry (140.77 g) seasons; likewise, differences were found for carcass yield (%), with 88.17 % and 86.89 % for the rainy and dry seasons, respectively. It is evident that in the rainy season there is an increase in their productive behavior. In terms of physicochemical performance, both seasons do not influence the chemical characteristics
Discontinuation of therapy in inflammatory bowel disease: Current views
Authors: Meštrović Antonio , Kumric Marko , Bozic Josko
Published: April 2024

The timely introduction and adjustment of the appropriate drug in accordance with previously well-defined treatment goals is the foundation of the approach in the treatment of inflammatory bowel disease (IBD). The therapeutic approach is still evolving in terms of the mechanism of action but also in terms of the possibility of maintaining remission. In patients with achieved long-term remission, the question of de-escalation or discontinuation of therapy arises, considering the possible side effects and economic burden of long-term therapy. For each of the drugs used in IBD (5-aminosalycaltes, immunomodulators, biological drugs, small molecules) there is a risk of relapse. Furthermore, studies show that more than 50% of patients who discontinue therapy will relapse. Based on the findings of large studies and meta-analysis, relapse of disease can be expected in about half of the patients after therapy withdrawal, in case of monotherapy with aminosalicylates, immunomodulators or biological therapy. However, longer relapse-free periods are recorded with withdrawal of medication in patients who had previously been on combination therapies immunomodulators and anti-tumor necrosis factor. It needs to be stressed that randomised clinical trials regarding withdrawal from medications are still lacking. Before making a decision on discontinuation of therapy, it is important to distinguish potential candidates and predictive factors for the possibility of disease relapse. Fecal calprotectin level has currently been identified as the strongest predictive factor for relapse. Several other predictive factors have also been identified, such as: High Crohn's disease activity index or Harvey Bradshaw index, younger age (< 40 years), longer disease duration (> 40 years), smoking, young age of disease onset, steroid use 6-12 months before cessation. An important factor in the decision to withdraw medication is the success of re-treatment with the same or other drugs. The decision to discontinue therapy must be based on individual approach, taking into account the severity, extension, and duration of the disease, the possibility of side adverse effects, the risk of relapse, and patient’s preferences.
Two-stage extraction by partial grinding of impacted mandibular third molar in close proximity to the inferior alveolar nerve
Authors: Luo Guang-Ming , Yao Zhang-Shun , Huang Wei-Xiang , Zou Lei-Yan , Yang Yan
Published: April 2024

BACKGROUND

Extraction of impacted third molars often leads to severe complications caused by damage to the inferior alveolar nerve (IAN).

AIM

To proposes a method for the partial grinding of an impacted mandibular third molar (IMM3) near the IAN to prevent IAN injury during IMM3 extraction.

METHODS

Between January 1996 and March 2022, 25 patients with IMM3 roots near the IAN were enrolled. The first stage of the operation consisted of grinding a major part of the IMM3 crown with a high-speed turbine dental drill to achieve sufficient space between the mandibular second molar and IMM3. After 6 months, when the root tips were observed to be away from the IAN on X-ray examination, the remaining part of the IMM3 was completely removed.

RESULTS

All IMM3s were extracted easily without symptoms of IAN injury after extraction.

CONCLUSION

Partial IMM3 grinding may be a good alternative treatment option to avoid IAN injury in high-risk cases.
Being a specialist is one thing, getting a job is another
Authors: Crean StJohn
Published: March 2024

Our editor explores the enduring need for specialist dental healthcare workers and how specialists will play a key role in reducing waiting times for patients seeking dental care.
Comment from the Dean
Authors: Eckhardt Charlotte
Published: March 2024

Our FDS Dean looks at the work being done across the royal colleges to ensure a high standard of assessment for those in specialist training.
People, priorities and pillars: supporting the dental school mission
Authors: Thomson Peter
Published: March 2024

As Peter Thomson returns to the UK to commence his post as head of dentistry at the University of Central Lancashire, he reflects on the dental school's mission in the 21st century, and considers how people, strategic priority setting and robust academic support pillars all help to underpin the delivery of modern dental education, research and clinical practice.
April 2024 Medical Image of the Month: Wind Instruments Player Exhibiting Exceptional Pulmonary Function
Authors:   Pulmonary & Critical Care, SSM Health, Danville, IL USA, Ali Abdulmonam
Published: April 2024

No abstract available. Manuscript truncated after 150 words. A 64-year-old man was referred to our pulmonary clinic for evaluation of his pulmonary status. He had a 7-year history of rheumatoid arthritis and was treated initially with steroids and subsequently maintained on methotrexate and monthly adalimumab injections monthly. The patient reported that his rheumatoid arthritis symptoms were controlled. He experienced no joint pain or morning stiffness at the time of evaluation. From a pulmonary perspective, he denied respiratory symptoms such as exertional shortness of breath, cough, wheezing, or chest tightness. He reported no limitations in physical activities. The patient has an occupational history of 45-years as a welder, with exposure to dust, metal fumes, benzene, and sulfur gas. The patient also has a 15 pack-year smoking history but quit 35 years ago. A high-resolution chest CT (Figure 1) ordered by his rheumatologist showed normal lung parenchyma. The first pulmonary function test (PFT), conducted on the initial pulmonary clinic visit …
The Circulation of Troubadour Music between Southern Languedoc and the Crown of Aragon
Authors: Talfani Camilla
Published: April 2024

Abstract: This study investigates the possible circulation of common compilation sources between southern Languedoc and the territories of the Crown of Aragon, sources which very probably contained both the text and the melody of troubadour songs. Though we have a very limited number of surviving troubadour melodies, certain clues reveal that Languedoc troubadour chansonniers (songbooks) C, E , and R and Catalan chansonnier V shared some common materials also available for copying music, which only chansonnier R conserves. A comparative analysis of the common transmitted texts, for which the four manuscripts manifest various affinities, shows that for most of these texts the melody is currently preserved by at least one of the four troubadour music witnesses.
Strong multiperiod forerunning light jet within a double-prism gap: a counterintuitive manifestation of causality
Authors: Turchin Alexander V. , Vasnetsov Mikhail V.
Published: April 2024

We report on the effect of a strong and protracted advanced response in pulse transmission and reflection in a double-prism scheme. In distinction to the well-known activity on superluminal-like tunneling of an electromagnetic pulse through a gap of a double prism, we consider an optical pulse refracting to a gap and sliding therein. The formation of a multiperiod light jet running within the gap well before the incident pulse is shown with account of normal material dispersion and excitation of leaky modes in the gap. Conditions for the paradoxical appearance of the forerunning jet are revealed to have a geometrical nature with a specific relation between phase and group velocities involved. This deduction assigns the stated effect to the counterintuitive manifestation of causality with no reference to superluminal propagation.
Extracting correlation length in Mott insulators by strong-field driving
Authors: AlShafey Abdallah , Jia Xu-Yan , Lu Yuan-Ming , Gong Shou-Shu , McCaul Gerard , Bondar Denys , Randeria Mohit , Oka Takashi , Landsman Alexandra S.
Published: April 2024

The breakdown of a Mott-insulator when subjected to intense laser fields is characterized by the formation of doublon-hole pairs. This breakdown is furthermore evidenced by the production of high harmonics that can be experimentally measured. Here, we present an approach for extracting the doublon-hole correlation length of a Mott insulator. The method is based on a dynamical calculation of the Mott insulator’s rate of charge production in response to an applied strong-field laser pulse. We find that coupling the Mott insulator to a metal drastically increases the correlation length, in support of our recent hypothesis [Phys. Rev. B 108, 144434 (2023)2469-995010.1103/PhysRevB.108.144434] that coupling to a metal enhances the charge fluctuations in the insulator. We confirm our conclusions using density matrix renormalization group (DMRG) calculations. The proposed method can be applied to experimentally measured observables, such as differential reflectivity or the high harmonic generation (HHG) spectrum to extract doublon-hole correlation length.
Infusing behavior science into large language models for activity coaching
Authors: Hegde Narayan , Vardhan Madhurima , Nathani Deepak , Rosenzweig Emily , Speed Cathy , Karthikesalingam Alan , Seneviratne Martin
Published: April 2024

Large language models (LLMs) have shown promise for task-oriented dialogue across a range of domains. The use of LLMs in health and fitness coaching is under-explored. Behavior science frameworks such as COM-B, which conceptualizes behavior change in terms of capability (C), Opportunity (O) and Motivation (M), can be used to architect coaching interventions in a way that promotes sustained change. Here we aim to incorporate behavior science principles into an LLM using two knowledge infusion techniques: coach message priming (where exemplar coach responses are provided as context to the LLM), and dialogue re-ranking (where the COM-B category of the LLM output is matched to the inferred user need). Simulated conversations were conducted between the primed or unprimed LLM and a member of the research team, and then evaluated by 8 human raters. Ratings for the primed conversations were significantly higher in terms of empathy and actionability. The same raters also compared a single response generated by the unprimed, primed and re-ranked models, finding a significant uplift in actionability and empathy from the re-ranking technique. This is a proof of concept of how behavior science frameworks can be infused into automated conversational agents for a more principled coaching experience.
Associação do uso de HArmonyCa® e ultrassom microfocado no rejuvenescimento facial
Authors: Bellini Michele Cristina Zanetti Silva , Queiroz Thallita Pereira , Jellmayer Juliana Aparecida , Camargo Mariana Santoro de
Published: April 2024

Introdução: O envelhecimento facial é complexo e ocorre como resultado da redução de substâncias essenciais, exposição ambiental e predisposição genética. Procurando por métodos menos invasivos para compensar os pilares do envelhecimento, preenchedores como ácido hialurônico (HA) e hidroxiapatita de cálcio (CaHA) têm ganhado popularidade. O HA promove volumização por 6-18 meses, dependendo do seu G prime; enquanto a CaHA, composta por microesferas de hidroxiapatita de cálcio suspensas num gel carreador aquoso, atua como suporte estrutural temporário e estimula a produção de colágeno. Recentemente, foi desenvolvido o HArmonyCa®, uma nova tecnologia de injetor híbrido que apresenta essas duas substâncias em sua composição, respondendo às necessidades multidimensionais do envelhecimento da face, de uma forma que a maioria dos agentes únicos não conseguem. Esse produto proporciona um efeito lifting imediato e estimulação sustentada de colágeno. Concomitantemente, o ultrassom microfocado surge como uma estratégia destinada a combater rugas e flacidez facial. Por meio da aplicação controlada de calor, esse método visa estimular a produção de colágeno e elastina, desencadeando a contração da pele e a reestruturação da derme. Objetivo: Esse estudo objetiva, através do relato de um caso clínico, avaliar a melhora clínica do contorno e flacidez facial, e eficácia da associação do ultrassom microfocado e HArmonyCa®. Conclusão: Concluiu-se que a combinação do ultrassom microfocado e HArmonyCa® pode ser uma boa opção para o tratamento de rejuvenescimento, obtendo o efeito de lifting facial.
The Impact of Stress and Workload on Performance Moderated by Work Shift
Authors: Pangabean Royhan Kamal , Junita Audia , Miraza Zuwina
Published: March 2024

The objective of this research is to investigate the impact of stress and workload on the performance of PT Cheil Jedang Feed Medan's employees, moderated by work shifts. The study is explanatory and employs a quantitative approach. Primary data was collected by distributing questionnaires to a sample of 101 employees. The sample size was determined using the saturated sampling technique. The data was analyzed using multiple linear regression and moderation regression analysis. The study found that workload has a significant negative impact on employee performance, but work stress does not. Furthermore, the work shift variable has no significant moderating effect on the impact of stress and workload on employee performance at PT Cheil Jedang Feed Medan. Based on the results of this research, it turns out that these variables contribute minimally to employee performance. Practical suggestions that need to be perfected by PT Cheil Jedang Feed Medan are improvements in the aspect of the speed of rotation of working hours between employees and the provision of rest periods according to the relatively high level of stress and workload felt by employees
Merajut Asa Kita (Knitting Our Hope): The Role of Rebranding in Developing Binong Jati Tourism Urban Village Brand Image
Authors: Allikanaya Primaura Meiracaesara , Hermawan Daniel
Published: March 2024

Binong Jati is one of the creative tourism urban villages created by the Bandung city administration as part of a program to boost the tourism industry. After 58 years, rebranding was required to alter the image of the Binong Jati knitting industrial center into the Binong Jati creative tourism urban village. This study sought to evaluate the impact of rebranding on brand image through repositioning, renaming, redesigning, and relaunch dimensions. One hundred twenty-nine visitors to the Binong Jati creative tourism urban village were polled online using quantitative research and purposive sampling. Multiple linear regression was used to analyze the data with IBM SPSS Statistics 25. According to the findings, rebranding affected brand image by 60%. The brand image was significantly impacted by repositioning, renaming, and relaunch, with relaunch having the most effect. These results can be used by management to strengthen the rebranding effort and better how the general public perceives the community.
Improving Customer Data Quality on Pension Bank Loans in Palembang-South Sumatra
Authors: Herlina Herlina , Muyasaroh Muyasaroh , Hairunnisa Hairunnisa
Published: March 2024

The bank has transferred the retirement loan application service to the cooperative as one of its subsidiaries. The phenomenon that often occurs is misinformation from cooperative officers when explaining the number of credit applications that should be made. The purpose of this research is to find the right pattern and form for applying the latest data technology so that it can provide the right information in the credit application process. Measurement and analysis of research data are qualitative, with a descriptive explanation level. Viewed by place and classified as field research. Types and research strategies, including Case Studies. Retrieval, collection, and analysis techniques were carried out repeatedly and simultaneously until the data was saturated and credible. The research yields findings about internal customer data connection patterns that are accurate and up-to-date. The form of credit data management by providing recommendations and internal references to customer performance, so that process and procedure connectivity is guaranteed between Bank Financial Institutions (LKB) and Non-Bank Financial Institutions (LKBB). The conclusion from the research is that the track records or data records of retired customers at the bank must be properly and up-to-date so that when applying for the same credit at a subsidiary of the institution, there is no misunderstanding of information and guaranteed correct and correct data.
PELAKSANAAN PENCEGAHAN DAN PENGENDALIAN INFEKSI (PPI) DI PUSKESMAS TEMANGGUNG SELAMA MASA PANDEMI COVID-19
Authors: Ahmad Nurul Fauziah
Published: March 2024

The spread of COVID-19 has also affected primary health services, including the Puskesmas Temanggung, or Indonesian Primary Health Care which is located in Temanggung Regency, Central Java Province. Based on the regulation of the Minister of Health Number 43 of 2019 concerning Community Health Centers, it is known that the Puskesmas, is responsible for implementing health policies, including policies for preventing and controlling COVID-19 infections. The research, which was conducted from October to November 2022, adapted a qualitative research design with an analytic descriptive approach. Based on this research, it was found that the communication aspects that affected Infection Prevention and Control, namely transmission, clarity and consistency, were good. While in the aspect of resources found deficiencies in infrastructure and capabilities of human resources. Dispositional aspects are less found in implementing commitment. Meanwhile, in the aspect of bureaucratic structure, there are deficiencies in the Standart Operating Procedure (SOP) for several precautions.
Analisis Potensi Penularan Tuberkulosis Paru di RW 10 Desa Kedung Waringin, Kecamatan Bojonggede, Kabupaten Bogor
Authors: Maharani Annisa
Published: March 2024

The Case Notification Rate at 2019 in Bogor Regency is 274 per 100,000 population. The Success Rate in 2019 was 89,29%, this figure was close to the target of 90%. The condition of the physical environment of the house is one of the factors that can cause the transmission of pulmonary tuberculosis. This objective is to analyze the potential for pulmonary tuberculosis transmission in RW 10 Kedung Waringin Village, Bojonggede District, Bogor Regency. This type of research is quantitative descriptive analytic research. The sampling technique uses accidental sampling. The number of samples is 100 houses. Data analysis in this study used univariate analysis techniques and potential analysis. The results of this study indicate that the most influential variables in the transmission of pulmonary tuberculosis in RW 10 Kedung Waringn Village are ventilation area, humidity, and lighting. Based on the calculation, the average result (mean) for the research variable is 2,5. Where this figure shows that the potential level of pulmonary tuberculosis transmission in RW 10 Kedung Waringin Village is included in the high category. The suggestions from this research are being able to improve the condition of the physical environment of the house so that it fits the criteria for a healthy house, increasing counseling efforts related to tuberculosis and healthy homes, and fostering the community to increase awareness of the surrounding environment if there are pulmonary tuberculosis sufferers.
FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN PENGGUNAAN METODE KONTRASEPSI JANGKA PANJANG (MKJP) PADA WANITA USIA 15-49 TAHUN DI WILAYAH PEDESAAN DI INDONESIA (ANALISIS DATA SDKI 2017)
Authors: Putri Naura Athira , Ronoatmodjo Sudarto
Published: March 2024

The Long-Term Contraceptive Method (LTCM) is a contraceptive method that can be used for a long time, start from 3 years to permanent. Contraceptive method that are included in LTCM are IUD, implant, tubectomy, and vasectomy. According to the 2017 IDHS data, LTCM utilization prevalence is much lower in number, compared to the Short-Term Contraceptive Method utilization, even though LTCM is more efficient and safe way to prevent pregnancy. The most used contraceptive method is injectables (29%) and pills (12%) Meanwhile, there are only 5% use IUD, 5% use Implant, 4% use tubectomy, and <1% use vasectomy. This study’s objective is to describe the prevalence of LTCM utilization in Indonesia’s rural areas, describe the individual characteristics in Indonesia’s rural areas, and determine the associated factors of LTCM utilization in women aged 15-49 in Indonesia’s rural areas. This is a cross-sectional study using secondary data from IDHS 2017. The analysis used in this study is Chi-Square test and Cox Regression test. The results found that there are significant association between age (APR = 1,4; 95% CI = 1,28-1,56), education level (APR = 1,3; 95% CI = 1,18-1,44), economic status (APR=1,2; 95% CI=1,05-1,33), parity (APR = 1,4; 95% CI = 1,24-1,51), knowledge of contraception (APR = 1,5; 95% CI = 1,32-1,59), source of contraception service (APR = 2; 95% CI = 1,80-2,20), family planning information exposure (APR = 1,1; 95% CI = 1,00-1,21), and partner support to the utilization of LTCM (APR = 1,7; 95% CI = 1,13-2,68). Source of contraception service is the predominant factor in this study (APR = 2; 95% CI = 1,80-2,20).
Exploring Endeavour of Health Facilitators Reinforce Public Consciousness on Stunting Reduction
Authors: Setiawan Koesworo
Published: March 2024

Health facilitators (IHT cadres/posyandu and village midwives) play a strategic role in preventing stunting. This study aims to uncover how health facilitators strengthen family awareness using Aristotle's persuasive analysis. Primary data were collected using in-depth interview techniques with informants determined by the purposive sampling method. Secondary data were collected by observation techniques during the interaction process between health facilitators and target groups and literature studies. Next, the data was encoded and analysed with Aristotle's three persuasive concepts: ethos, pathos, and logos. The results showed that health facilitators interacted directly with the target group through two important moments: during health checks at posyandu, and sweeping people's homes. The facilitator's knowledge is sourced from MCH books and other valid references. In conclusion, the facilitator applies interpersonal communication (counseling) to reinforce consciousness of the target group, which is reinforced by Aristotle's persuasion techniques: ethos, pathos, and logos. Through direct interaction, they convince and change family views, beliefs, and behaviours to comply with stunting guidelines. Facilitators promoted three key messages in strengthening consciousness: maternal and child health, healthy behaviours and lifestyles, and environmental health.
Pengaruh social support dengan peer leader untuk meningkatkan self management diabetic pada sesama penderita DM tipe II di Posyandu Lansia
Authors: Khairani Wittin , Purwanti Nunuk Sri
Published: March 2024

ABSTRACTThe phenomenon of cases of diabetes mellitus from year to year continues to increase. According to the International Diabetes Federation (2019) revealed that the number of diabetes mellitus patients in the world in 2019 was 829 million and it is estimated that in 2040 the number of diabetes patients will increase 1.5 times. The prevalence of diabetes mellitus in the Special Region of Yogyakarta continues to increase every year. The prevalence of Diabetes Mellitus in DI Yogyakarta Province, in 2020, is 5.59 percent. This figure has even increased compared to the results of research seven years earlier in 2013, namely 3.4 percent.To determine the effect and differences in increasing diabetic self-management before and after intervention through social support with peer leaders among people with type II DM in the elderly Posyandu.This research used a quasi-experimental design with a pre-test and post-test nonequivalent control group design. The study population was all type II diabetes sufferers at the Elderly Posyandu in Ngentak, Bangunjiwo, Kasihan, Bantul, DI Yogyakarta from September 2022 to June 2023 with a sample size of 50 respondents using purposive sampling. The data collection instrument used a respondent characteristic questionnaire, and a diabetes self management knowledge questionnaire. Data were analyzed univariately and bivariately with q-square test (95% CI). In this design, the experimental group underwent an initial selection in the form of a pre-test, namely the assessment of diabetic self-management in type II DM patients before the social support intervention with peer leaders was carried out, then a post-test was carried out after the intervention was given.There is an effect of increasing diabetic self-management knowledge, seen from the difference in the mean value from pretest to posttest of only 10,5 in the respondents' answers. There was a difference from the pretest to the posttest scores, seen from the significance of p = 0.000 (p <0.05) after being given interventions about social support with peer leaders among people with type II DM in the elderly Posyandu.There are influences and differences in the form of increasing diabetic self-management after being given intervention to fellow DM type II sufferers at the Elderly Posyandu in Ngentak hamlet, Bangunjiwo, DI Yogyakarta Keywords: Diabetic self management, social support, peer leader, type II diabetic
HUBUNGAN PENANGANAN KELUHAN (COMPLAIN HANDLING) DENGAN LOYALITAS PASIEN DI INSTALASI RAWAT INAP RSUD PETALA BUMI PROVINSI RIAU
Authors: Safitri Yuni Asnita Adetia , Tonis Marian , Suryandartiwi Wiwik
Published: March 2024

Penanganan keluahan merupakan identifikasi masalah yang menyebabkan pasien atau pelanggan tidak puas dan mengeluh sehingga menindaklanjuti dan diupayakan agar pasien atau pelanggan merasa ada perbaikan dari masalah atas ketidaksesuaian harapan dari pelayanan yang diberikan rumah sakit. Akibatnya banyaknya rumah sakit ikut menurun dan berpengaruh dengan loyalitas pasien. Loyalitas pasien memiliki peranan penting dalam suatu rumah sakit atau perusahaan untuk meningkatkan performa finansial, dan sustainability dari rumah sakit. Tujuan dari penelitian ini untuk mengetahui hubungan penanganan keluhan (complain handling) dengan loyalitas pasien diinstalasi rawat inap RSUD Petala Bumi. Jenis penelitian ini yaitu kuantitatif dengan metode probability sampling. Sampel dalam penelitian ini pasien rawat inap RSUD Petala Bumi Provinsi Riau sebanyak 86 responden. Penelitian ini dilaksanakan dengan Teknik pengumpulan data studi pustaka dan penyebaran kuesioner. Analisis pada penelitian ini univariat, bivariat, normalitas, dan linearitas. Hasil penelitian menunjukkan bahwa variabel visibility adanya hubungan dengan loyalitas pasien (p-value= 0,000 < 0,05), bahwa variabel accesbility adanya hubungan dengan loyalitas pasien (p-value= 0,030 < 0,05), bahwa variabel responsive adanya hubungan dengan loyalitas pasien (p-value= 0,000 < 0,05) dan bahwa variabel fairness and objektif adanya hubungan dengan loyalitas pasien (p-value= 0,000< 0,05). Kesimpulan penelitian ini adalah bahwa pasien rawat inap di RSUD Petala Bumi Provinsi Riau merasa puas terhadap penanganan keluhan yang diberikan. Dapat diartikan pelayanan yang diberikan memenuhi dan keinginan pasien sehingga terciptanya loyalitas pasien di RSUD Petala Bumi.
Hubungan Dukungan Sosial dan Beban Kerja Mental dengan Burnout Syndrome Pekerja PT Trans Marga Jateng
Authors: Ardiningrum Nur Annisa , Atmojo Tutug Bolet , Wijayanti Reni
Published: March 2024

Burnout syndrome is a condition of physical, mental and emotional exhaustion due to stress that results from long-term involvement in emotionally demanding situations. In Indonesia, 83% of health workers experience moderate and severe burnout syndrome. Factors that cause burnout syndrome that have a strong and consistent relationship are social support and workload. This study aims to determine the relationship between social support and mental workload with burnout syndrome. This research is an analytical observational study, with a cross sectional design. Respondents were taken from PT Trans Marga Jateng toll road operational workers, with 85 respondents from a total of 230 workers using a purposive sampling technique. This study uses a validated questionnaire to measure burnout syndrome, social support, and mental workload of workers. The data analysis technique used are somers'd correlation test and ordinal logistic regression test. The results showed that the majority of respondents experienced moderate category of burnout syndrome, good category of social support, and moderate category of mental workload. The results of the somers'd correlation test showed that there was a significant relationship between burnout syndrome and social support (p = 0.001) with the negative correlation direction and weak correlation strength (r = -0.354), and there was a significant relationship between burnout syndrome and mental workload (p = 0.000) with a positive correlation and moderate correlation strength (r = 0.506). The results of the ordinal logistic regression test show that the mental workload variable has a stronger influence on burnout syndrome than the social support variable.
Commercial Corridor Development Strategy through the Application of the Walkable Commercial Strip Concept in Urban Area of Jember City
Authors: Sulistyono Sonya , Koesoemawati Dewi Junita , Hayati Nunung Nuring , Angelina Callista
Published: March 2024

Walkability is an essential concept to consider when planning a sustainable city. This study aims to determine the walkability development strategy of the Jember City commercial corridors urban area based on people's and experts' perceptions of the Walkable Commercial Strip concept. The study was conducted in the urban area of Jember City Golden Triangle. The methods of analysis used in this study are ordinal logistic regression and AHP. Based on people's perceptions, the concepts that have the highest odds of influencing the first corridor's walkability level are the ones related to the available amenities variable, while the concept that has the highest odds of influencing the second and the third corridors' walkability level is the concept that is related to the walking path modal conflict variable. The order in which corridors have the highest development priority starts with the first corridor, Gajah Mada - Sultan Agung Street, followed by the second corridor, Ahmad Yani Street, and ends with the third corridor, Trunojoyo Street – HOS Cokroaminoto Street. The walkability development strategy for the urban area of Jember City commercial corridors is to start the order of development according to the order of priority and apply the development concepts that have the highest opportunity to influence the walkability level of each corridor based on people's perception.