bluuebunny/crossref_metadata_2025 huggingface dataset:
INTELLIGENT TRAFFIC CONTROL DEVICE MODEL USING AD HOC NETWORK
Authors: Bestak Robert
Published: March 2020

The advancements in the technologies related to the wireless communication systems has made the vehicular adhoc networks prominent area of research in the automobile industry. The absolute volume of road traffic affects the safety, convenience and the efficiency of the traffic flow in the urban areas. So the paper scopes in developing an intelligent traffic control device model using the adhoc network to ameliorate the traffic flow. The proposed system enhances the convenience in travel by gathering the information of the vehicles along with the density of the vehicles and the movement of the vehicles on road. The device is modelled using the MATLAB and examined over the traffic flow on the peak hours as well as the normal hours and the holidays to understand its intelligent traffic control. The results obtained shows that the performance improvement in optimizing the traffic congestion through the proposed method is better compared to the existing methodologies used in traffic controlling.
MACHINE LEARNING BASED AUTOMATIC PERMISSION GRANTING AND MALWARE IDENTIFICATION
Authors: M. Duraipandian , R. Vinothkanna
Published: March 2020

The mobile device have gained an imperative predominance in the daily routine of our lives, by keeping us connected to the real world seamlessly. Most of the mobile devices are built on android whose security mechanism is totally permission based controlling the applications from accessing the core details of the devices and the users. Even after understanding the permission system often the mobile user are ignorant about the common threat, due to the applications popularity and proceed with the installation process not aware of the targets of the application developer. The aim of the paper is to devise malware detection with the automatic permission granting employing the machine learning techniques. The different machine learning methods are engaged in the malware detection and analyzed. The results are observed to note down the approaches that aids better in enhancing the user awareness and reducing the malware threats, by detecting the malwares of the applications.
ELASTIC CLOUD COMPUTING APPROACH FOR BIG DATA ANALYTICS
Authors: V Suma
Published: March 2020

The latest developments in the communication and the information technologies have turned out to be the foundation
for the emergence of the industrial developments and progress in the business causing digital transformation in the industrial and
the business operations. The clubbing of the internet and the information technology along with the tangible things that are the
responsible for the industrial operations, generate a huge set of data that requires enormous network bandwidth, high processing
power and accessible resolutions. So the paper presents the elastic cloud computing approach to bring down the complexities in
deploying, cost of the groundwork and maintenance and provide an automated resource provisioning according to the demands.
This method increases the amount of the computing power available, network properties and the storage. The experimental
results for the novel elastic approach for the big data analytics is obtained by the simulation through MATLAB in terms response
time, processing power and cost.
SECURITY OF TECHNICAL DEVICES WITH THE USE OF RESOURCE-STRENGTHENING RESEARCH COMPLEX
Authors: Cherepanov Anatoliy , Lyapustin Pavel , Nikanorova Lyudmila , Loseva Marina
Published: March 2020

The article deals with the application of a complex of resource-strength studies of

complex technical devices for processing the results of technical diagnostics.
A IMPORTÂNCIA DA TECNOLOGIA DA INFORMAÇÃO NO PROCESSO DE TOMADA DE DECISÃO
Authors: Marques Felix Gabriela , Verginio da Silva Sidney
Published: March 2020

O atual trabalho tem por objetivo trazer uma discussão sobre a tecnologia da informação e sua importância nas tomadas de decisões dentro das organizações. Por meio de revisão bibliográfica pôde-se entender o cenário em que o Brasil está inserido no que tange ao setor de tecnologia da informação em comparação a outros países, sendo, em 2018, o nono país que mais investiu no setor. A tecnologia da informação é essencial, pois as empresas se encontram imersas nas imposições tecnológicas e competências relacionadas ao modelo proposto pela Quarta Revolução Industrial, em que a importância do investimento em conjunto de ferramentas e metodologias de análise de grandes volumes de dados é imprescindível. O estudo em questão demonstrou que mais da metade das empresas brasileiras se consideram fortes no quesito análise de dados, mas apenas 1% de todos os dados gerados são de fato estruturados, usados e analisados. A importância do tema se encontra no fato de que o processo de tomada de decisão atualmente deixa de ser feito apenas com base em experiências e instinto e passa a ser feito tendo como ferramenta tecnologias que processam, analisam e transformam dados desestruturados em informações completas e valiosas que embasam, através de fatos, números previamente tratados e analisados, as decisões tomadas
Managing data flows in infrastructure projects - the lifecycle process model
Authors: Halttula Heikki , Haapasalo Harri , Silvola Risto
Published: March 2020

Productivity in the construction industry (both houses and infrastructure) has not been improving as expected, while other industries have been able to improve their productivity significantly. The appropriate use of building information modelling (BIM) technologies brings several benefits and advantages to construction projects. The main challenges of project efficiency emerge in the form of numerous requests for information during the construction project, which are considered to be waste in the processes. This highlights the need for a practical process model to plan the information flow for BIM-based projects. The main aim of this study is to propose a model to plan the flow of project information among primary stakeholders especially in infrastructure projects. Our main findings are firstly, the foundation for data management starts from defining unified one data for the product and the for the process. Unified data means one single repository of data – all stakeholders use the same unified data. It is also essential that data responsibilities and ownership are defined. Secondly, we found that the biggest challenges are that the data needs are not planned beforehand, resistance to change, difficulty receiving existing data and data must be modified before use. As a whole, it seems sometimes that the technology on data transfer is more important that what has been transferred and why. Finally our construction, the life cycle model for data flow originates from one data to all stakeholders, single data repository must be updated along the life- cycle of the object covering also the operations and maintenance, where the data has to be updated through the whole life-cycle. This new approach is intended to enable the early involvement of maintenance stakeholders in designing product data for a project lifecycle perspective. The model helps to change the current information flow and gain the benefits that a BIM-based process can offer. This study is based on case studies and is qualitative in nature and naturally needs more validation.
Market Reactions to Announcements of Valuation Losses on Conversion Rights Embedded in Convertible Instruments
Authors: Lee Su Jeong , Kim Young Jun , Lee Eugenia Y. , Choi Ga-young
Published: March 2020

Convertible instruments are financial instruments embedded with conversion rights such as convertible bonds or convertible preferred stocks. Under the Korean International Financial Reporting Standards (K-IFRS), the embedded conversion rights with certain conditions (i.e., a refixing clause) are recognized as derivative liabilities and are recognized at fair value in issuer’s financial statements. Since the value of convertible rights varies with the underlying stock value, an increase in the issuers’ stock price causes the issuers of convertible instruments to announce large derivative valuation losses. Using disclosures under the title of ‘Loss from Derivatives Trading’ from the KOREA EXCHANGE (KRX) during January 2016 through December 2019, this study examines market reactions to the disclosure of valuation losses on conversion rights embedded in convertible instruments. We find the following results. First, abnormal stock returns on the loss announcement date are significantly negative. Second, abnormal trading volumes peak on the loss announcement date. Third, abnormal stock returns persist in the long-term. Collectively, our findings suggest that investors perceive the loss disclosures as negative news, but fail to impound the information into issuer’s stock prices effectively. This study emphasizes the importance of education on convertible instruments and improvement in the disclosure requirements on valuation losses of conversion rights embedded in convertible instruments by providing evidence that investors face difficulty in understanding the related disclosures.
The Impact of Risk Anomalies on the Pharmaceutical Sector of the Indian Stock Market. A comparative analysis between pharmaceutical, FMCG and IT companies
Authors: Pinto Prakash , Hawaldar Iqbal Thonse , Kemminje Guruprasad , Rohit Babitha , Spulbar Cristi Marcel , Birau Felicia Ramona , Stanciu Cristian Valeriu
Published: March 2020

The main purpose of this research article is to provide a comparative framework on various implications of risk anomalies on Indian stock market based on an empirical study for the following sectors: Pharmaceutical, Fast-Moving Consumer Goods (FMCG) and IT. Risk anomaly is a notable anomaly because it is continual and all-inclusive. This research study aims to examine the existence of risk anomaly in the National Stock Exchange, India, and in particular providing a comparative analysis on the behavior of the pharmaceutical sector in India.
Analysis of Corrosion Products Transported through Secondary Side of Candu Steam Generator Using GIXRD
Authors: Dinu Alice , Tunaru Mariana
Published: March 2020

To verify the chemistry of secondary side of CANDU steam generators, Millipore filters are used to sampling from condensing extraction pump, feed water header and blow down of steam generator. These filters retain the corrosion products as very fine particles and are used as samples in chemistry water control. X-Ray diffraction (XRD) is the most used technique that can provide information about the phase composition of analyzed samples. Because the crud layers on the Millipore filters are very thin, to identify the corrosion products Grazing Incidence X-Ray diffraction (GIXRD) technique was used. The following compounds have identified: magnetite (Fe3O4), hematite (Fe2O3), and iron oxide hydroxide (FeOOH). It was observed a brown-reddish background specific to hematite and iron oxide hydroxide, especially for filters extracted from condensing extraction pump. The black colour of crud present on filters extracted from feed water header and blow down of steam generator shows the presence of magnetite.
Contributions to the Interpretation of Mass Spectrum of Tetraethoxysilane (TEOS). III. Accurate mass and M+1, M+2 isotopic effect measurements
Authors: Badescu Virgil
Published: March 2020

The aim of this article in continuation of Parts I [1] and II [2] is the interpretation of the TEOS mass spectrum as a precursor in the sol-gel process. In Part I [1] the primary fragmentation ions at masses 207, 193, 179 and 163 were obtained experimentally by B/E linked scan by radical induced fragmentation reactions. In Part II [2] eliminations of neutral fragments from the primary ions and the obtained ions by consecutive elimination reactions were evidenced experimentally by the B/E and B/E(1-E)1/2 linked scans. In this third and final Part of interpretation of the TEOS mass spectrum, the separation of ions by mass spectrometry at high resolutions of 5000 and 6600, relative to standard resolution 1000, and measurements of the M+1 and M+2 isotopic effects at the resolution of 5000 are presented. The separation of the ions with nominal mass 105 at high resolution is detailed.
Screening for Hypertensive Pregnancy Complications through Maternal Serum PAPP-A 5th and 10th Percentiles during the 11-14 Weeks Gestational Age Interval
Authors: Dascau Voicu , Furau Gheorghe , Pilat Luminita , Onel Cristina , Puschita Maria
Published: March 2020

The aim of our study was to assess the predictive values for hypertensive complications of pregnancy of the multiples of median (MoM) of serum pregnancy associated plasma protein A (PAPP-A), measured in 128 pregnant patients between 11 and 14 weeks gestational age. The 5th and the 10th percentile for MoM PAPP-A were 0.27 and 0.33, respectively. The detection rate for pregnancy induced hypertension, mild preeclampsia, severe preeclampsia, all preeclampsia and all hypertensive complications was 0%, 9.09%, 0%, 7.69%, and 6.25% for MoM PAPP-A below the 5th percentile (for a false positive rate of 5%), and 33.33%, 9.09%, 0%, 7.69%, and 12.5% for MoM PAPP-A below the 10th percentile (for a false positive rate of 10%), respectively. The specificity ranged from 89.57% to 95.73%, the positive predictive value from 0% to 16.67%, and the negative predictive value from 87.70% to 98.36%.
The Romanian Consumer Among Education, Information, Health Risk, Food Quality and Ethics
Authors: Voica Cezara , Rosu Cristina , Iordache Andreea Maria , Pistea Ioana Cristina , Miricioiu Marius Gheorghe
Published: March 2020

The food quality and the safety must be a constant concern both for consumers and for authorities. The education for quality and the active involvement, coherent and sustained by the state, through the implementation of a quality strategy at national level should be the main `forces` that can contribute to the implementation and certification of quality management systems in the agri-food sector. The meat and milk products are important components in the human diet; therefore, their contamination with heavy metals plays a significant role in the public health. The concentrations of several human essential trace elements (Mn, Cu, Zn and Ba) and toxic elements (As, Cd, Pb) were analysed in 95 animal-based foods, including meat, milk products and honey, collected from Romanian market. The inductively coupled plasma mass spectrometry technique (ICP-MS) was used for the determinations. In order to evaluate the potential health risk of the consumers due to metals intake via food ingestion, three indices were calculated, namely: the potential average daily dose (ADDpot, mg/kg/day), the hazard quotient (HQ) and the hazard index (HI). In terms of food safety, the toxic element concentrations in the majority of the investigated samples were below the maximum permitted levels set by Romanian and European legislation.
Eliminacinė kompleksinė dieta sergančiųjų atopiniu dermatitu (AD) odos būklei gerinti
Authors: Kurpienė Vaida , Kubilienė Erika
Published: March 2020

Klinikinio tyrimo tikslas – patvirtinti hipotezę, kad eliminacinės dietos taikymas gali pagerinti sergančiųjų atopiniu dermatitu (AD) odos būklę. Tiriamųjų kontingentas – vyresnių nei 22 metų asmenų, kuriems jau diagnozuota lėtinė uždegiminė odos liga (AD) ir tyrimo laikotarpiu nevartojančių geriamųjų kortikosteroidų, maitinimosi priežiūra. Tiriamųjų imtis – 28 tiriamosios grupės asmenys ir 30 kontrolinės grupės asmenų. Tyrimo metodai. 99 mokslinių straipsnių analizė, anketinė apklausa, tiriamųjų maitinimosi savikontrolės dienynų analizė, eliminacinio diagnostinio maitinimosi plano kvazieksperimentas. Tiriamiesiems buvo sudarytas mažo histamino kiekio valgiaraštis šešioms savaitėms, kuriame papildomai eliminuoti pieno ir glitimo turintys produktai. Kas dvi savaites buvo vykdoma tiriamųjų stebėsena, vertinami rezultatai ir lyginama su kontroline grupe. Rezultatai. Vidutinis SCORAD rodiklis, rodantis AD būklės sunkumą balais, sumažėjo beveik dukart (nuo 52,8 iki 28,04 balo). Sunkios AD būklės tiriamosios grupės tiriamųjų sumažėjo penkis kartus (nuo 57 iki 11 proc.), lengvos AD būklės tiriamųjų dalis išaugo iki 57 proc. Išvados. Atsižvelgus į tyrimo rezultatus, sergantiesiems AD galima rekomenduoti laikytis 4–6 savaičių eliminacinės diagnostinės kompleksinės dietos, kurios metu palaikomas mažas histamino kiekis, vengiama pieno ir glitimo turinčių produktų. Būklei pagerėjus, pacientui rekomenduotina tęsti tokį maitinimąsi, pamažu įtraukiant į dietą glitimo ir pieno turinčius produktus bei stebint odos pokyčius.
Atviros pilvo traumos šiuolaikinės gydymo tendencijos
Authors: Margelis Ernest , Kiudelis Mindaugas
Published: March 2020

Tyrimo tikslas – išnagrinėti atviros pilvo traumos savitumus, sunkumą ir gydymo rezultatus, nustatyti galimus prognostinius kriterijus, rodančius neatidėliotino chirurginio gydymo (laparotomijos) būtinybę. Tiriamųjų kontingentas. Lietuvos sveikatos mokslų universiteto ligoninės Kauno klinikų (toliau – Kauno klinikos) Chirurgijos klinikos pacientai, kurie 2006–2016 m. buvo gydomi dėl atviros pilvo traumos. Tyrimo metodika. Atlikta retrospektyvioji duomenų analizė. Į tyrimą įtraukti 93 pacientai, atitinkantys kriterijus: atvira pilvo trauma, taikytas chirurginis gydymo būdas. Nagrinėtos pacientų ligos istorijos, kurie 2006–2016 m. patyrė atvirą pilvo traumą ir buvo gydomi Chirurgijos klinikoje. Rinkti duomenys apie pacientų amžių, lytį, traumos pobūdį, gyvybinius rodiklius, laboratorinius ir vaizdinius tyrimus, laiką nuo sužalojimo iki operacijos, operacijos tipą, operacijos trukmę, gydymo trukmę, gydymo baigtis bei pooperacines komplikacijas. Rezultatai. Esant sistoliniam AKS mažiau nei 101 mm Hg st., leukocitų kiekiui kraujyje daugiau nei 9,1 × 109/l, hemoglobino kiekiui mažiau nei 110 g/l, C reaktyviajam baltymui daugiau nei 10 mg/l bei atliktame pilvo UG arba KT radus pokyčių, yra 3,4 karto didesnė tikimybė, kad yra kiaurinis pilvaplėvės sužalojimas kartu su pilvo organų pažeidimu.
Šeimos gydytojų perdegimo sindromo įveikimo būdai. Sisteminė literatūros analizė
Authors: Leonavičiūtė Joana Laima , Kontrimienė Aušrinė
Published: March 2020

Įvadas. Pasaulyje vis daugiau diskutuojama apie gydytojų perdegimo sindromą ir priemones, kaip jį įveikti. Šeimos gydytojai priskiriami vienai iš labiausiai perdegimo sindromą patiriančių specialybių. Šios sisteminės apžvalgos tikslas – aptarti tyrimų duomenis, atskleidžiančius, kokius būdus ir strategijas numato šeimos gydytojai, siekdami išvengti perdegimo sindromo darbo aplinkoje, o jam atsiradus, kaip jį bando įveikti. Tyrimo metodai. Sisteminė literatūros paieška atlikta Pubmed, EBSCO ir OVID duomenų bazėse, naudojantis Prisma rekomendacijomis. Sisteminės literatūros analizei pasirinkti specifiniai įtraukimo kriterijai: įtraukiami kokybiniai tyrimai, kurie tyrinėjo šeimos gydytojų taikomus būdus perdegimo sindromo problemai darbe įveikti. Duomenys analizuojami teminės analizės metodu. Rezultatai. Įtraukimo į tyrimą kriterijus atitiko šešios kokybinės studijos. Atlikus teminę analizę, išskirtos trys pagrindinės temos: 1) individualūs bei asmeninio gyvenimo veiksniai ir strategijos; 2) su darbo vieta ir profesija susiję veiksniai bei strategijos; 3) sisteminių pokyčių poreikis. Pirmoje temoje aptariama: asmeninės savybės ir požiūriai, santykiai, sveika gyvensena ir rekreacinės veiklos, įvairių (atsipalaidavimo) praktikų taikymas, darbo ir asmeninio gyvenimo pusiausvyros išlaikymas. Antroje temoje aptariama: darbo veiklos organizavimas, įvairesnis darbo ir kitos veiklos pobūdis, darbo krūvio mažinimas, bendradarbių palaikymas ir pagalba, bei pertrauka kaip fiziologinių ir socialinių poreikių tenkinimas. Trečioje temoje išskirta valstybės pagalba ir specifinių mokymų būtinybė. Išvados. Šeimos gydytojų perdegimo problemai spręsti reikėtų atsižvelgti į sistemines, įstaigos darbo organizavimo bei individualias priemones. Būtų tikslinga atlikti daugiau tyrimų mūsų šalies specifiniame sveikatos priežiūros kontekste siekiant nustatyti, kokios intervencijos ir kokie pokyčiai sveikatos priežiūros sistemoje būtų iš tikrųjų efektyvūs bei kokiu lygmeniu intervencijos būtų aktualios ir realiai įgyvendinamos sprendžiant perdegimo sindromo problemą.
Developing Teaching Immediacy in Language Teacher Education
Authors: Rugen Brian
Published: March 2020

Teacher immediacy refers to the verbal and non-verbal communication behaviors that reduce the psychological distance between a teacher and students. Despite the importance of these behaviors in supporting student learning, teacher immediacy has received little attention in the field of English language teacher training. In fact, in many teacher training and faculty development programs, the explicit teaching of these immediacy behaviors is often absent. In this article, I first present a brief review of the literature on teacher immediacy. Then, I describe the steps for two specific training practices for developing teacher immediacy. Both practices have been used successfully for several years in an MA TESOL teacher training program in Hawaii.

教師は、生徒との心理的距離を縮めるためにコミュニケーションを図る。この教師の近接性（teacher immediacy）の方法は、言葉を用いるだけではなく、言語外コミュニケーションを取ることもある。これらの具体的な行動（behaviors）は、教育において非常に重要であるにも関わらず、英語教員養成の中では軽視されている。実際、教員のための訓練や大学のファカルティ・ディベロプメント（FD）に、コミュニケーションの取り方（immediacy behaviors）は含まれていないことが多い。本論では、まず教師の近接性について、先行研究を元に説明する。次に、生徒とのコミュニケーション力を向上させるための2つの方法を紹介する。いずれの方法もハワイの教員養成プログラム（MA TESOL）で実践されており、長きにわたり成功を収めている。
Japanese Learners’ Consciousness Toward English: When Do They Begin to Like or Dislike English?
Authors: Matsuno Sumie
Published: March 2020

This paper provides a review of research addressing when students begin to like or dislike English, when they obtain or lose their motivation for learning English, and the reasons associated with their preferences and motivation regarding the language. It also includes a discussion of the findings of a qualitative survey conducted by the author, which indicates that the first and the second grades of junior high school are probably serious turning points of their consciousness toward English. The second biggest turning point is probably the first half of the first grade of high school. Once they have difficulty in learning English and begin to hate English, their feelings continue, even at the university level. The reasons for students’ dislike of English are often related to their difficulty with the language. For example, studying English is to memorize sentences and words, and learning English grammar is very difficult.

本論では、生徒が英語を好きになり始めたり嫌いになり始める時期やその動機、理由について過去の研究結果を調査している。また40名の大学1年生を対象にした質的調査を行った結果を述べている。この質的調査の結果はこれまでの研究結果を裏付けるもので、まず中学1年と2年の時期、次に高校1年の前半の時期が、英語に対する意識の最も重要なターニングポイントであることがわかった。また一度嫌いになるとその気持ちは大学生になっても続く傾向にある。嫌いになる要因としては英文や英単語の暗記、文法の難しさがあげられる。
Interview Testing: An Exploratory Study into the Use of Method Adjustment Strategy to Compensate for a Less Structured Interview Test
Authors: Nutt Julyan
Published: March 2020

An exploratory study was formulated to see whether instruction in strategic competence would better help students manage a less structured version of the pre-existing bi-semester interview test (B-test). Furthermore, the author hoped to determine whether the structured nature of the test was actually detrimental to the students’ communicative ability.

A study group of four higher-level English classes from two departments (two classes from each department), as determined by TOEIC bridge placement tests, was formed. One class each from both departments was designated a control group, and the other a strategy group that was instructed in method adjustment strategies. All four groups were given a supplementary interview test (S-test) made up of two each of five types of question variations of the original B-test questions. Students were then interviewed by the author and another teacher, and their scores and the strategies employed were recorded. Analysis revealed that while overall both strategy groups managed the S-Test better than their corresponding control group, the most revealing difference was that both the strategy and control group from one department scored significantly worse in the S-test than those in the other department (although they achieved higher scores in the B-test), despite that strategy group employing a wide variety of message adjustment strategies. It was therefore concluded that the message adjustment strategies taught should be mostly limited to utterances and shadowing, and the structured nature of the B-test be adjusted to accommodate alternative question types.

既存のあまり体系的ではないインタビュー式試験（B試験）に、2学期にわたって学生が対処する際、戦略的能力をつけることが彼らの助けになるかどうかを調査するため、探査的研究を行った。さらに、試験の体系的性質が実際には学生のコミュニケーション能力に有害かどうかを検討した。研究の対象として、TOEIC Bridgeのプレイスメントテストから判断した2つの 学科の学生から、比較的レベルの高い4 つの英語クラス（各学科から2 クラスずつ）のグループを作った。各学科で1 つのクラスを基準グループとし、もう1 つのクラスは戦略グループとして調整戦略法を教えた。全4 グループは補足のインタビュー式試験（S試験）を受けた。S試験は、元のB試験の設問のうち2 つに、それぞれ5タイプの設問のバリエーションを設けたものである。その際学生は、筆者と他1 名の教員によるインタビューを受け、得点と用いられた戦略が記録された。分析の結果、両戦略グループは全体として、比較対象となる基準グループよりS試験にうまく対処できたことが明らかになった。さらに最も顕著な違いは、1 つの学科の戦略グループと基準グループが共に、S試験においては他学科のグループより明らかに低得点であったことだ。（彼らはB試験においてはより高得点を達成していたし）、戦略グループは多様なメッセージ調整法を用いたにもかかわらず、である。ゆえに結論付けられたことは、メッセージ調整法の教授は発話と復唱にほぼ限るべきであり、B試験の体系的性質は、別の設問タイプに対応するために調整されるべきであるということである。
REVOLUSI INDUSTRI 4.0 PELUANG DAN TANTANGAN TERHADAP LEMBAGA PENDIDIKAN DALAM PERSPEKTIF TEKNOLOGI PEMBELAJARAN
Authors: Arnadi Arnadi
Published: March 2020

Revolusi industri 4.0 adalah merupakan titik pemberhentian sementara dari gerak laju teknologi, dan hal ini adalah hasil yang di dapat melalui usaha seseorang. Teknologi yang dihasilkan dapat berupa alat atau sarana baru dari hasil penemuan baru, atau hasil dari pengembangan teknologi sebelumnya yang mengarah pada hal yang lebih sempurna. Gerak laju teknologi dipastikan berpengaruh pada dunia pendidikan, termasuk pada teknologi pembelajaran dan kawasan- kawasan yang menyertainya. Gerak laju teknologi akan menjadi peluang yang sangat baik bagi dunia pendidikan, karena lembaga pendidikan akan semakin memiliki kesempatan untuk berinovasi dan berkreasi dalam kawasan teknologi pembelajaran, seperti model pebelajaran dengan aplikasi ruang guru yang sedang booming saat ini.
The Role of the Glucocorticoid System in Anchorage-independence during Progression of Squamous Cell Carcinoma
Authors: Kennedy David , Pignatelli Massimo , Hassona Yazan , Prime Stephen S. , Cirillo Nicola
Published: March 2020

Background: Topical and systemic corticosteroids are widely used for the treatment of mucocutaneous disorders including those with malignant potential. We have shown previously that normal keratinocytes regulate the local concentration of active steroids, as well as synthesize hydrocortisone de novo following stimulation with ACTH. The role of locally produced hydrocortisone in tumour progression is unclear.

Objective: To examine the ability of endogenously-produced and exogenously-administered hydrocortisone on the capacity of human keratinocytes to promote the formation of anchorage-independent multicellular aggregates (MCAs) in vitro.

Methods: The human keratinocyte cell line HaCaT derived from irradiated facial skin and c-Ha-ras-transfected HaCaT cell clones (I-7, II-3, RT-3) demonstrate increasing tumorigenic and metastatic potential in vivo and are ideally suited to studies of keratinocyte tumour progression. The formation of multicellular aggregates (MCAs) in vitro was used as a paradigm of metastatic potential in vivo.

Results: Non-tumorigenic (HaCaT), benign (I-7), malignant with low metastatic potential (II-3) and malignant with high metastatic capacity (RT-3) keratinocytes secreted basal levels of cortisol, activated cortisone and differentially synthesized cortisol de novo in the presence of ACTH; malignant cells (II-3 and RT-3) produced the highest levels of the steroid. When the cells were cultured in the absence of a substrate, RT-3 cell in particular were highly effective in forming MCAs and hydrocortisone further promoted MCA formation. Stimulation of the endogenous glucocorticoid system by ACTH caused an increase in MCA formation by II-3.

Conclusions: The data demonstrate that stimulation of the endogenous glucocorticoid system promotes anchorage independence of malignant keratinocytes in vitro.
A Panoramic Landscape of the Sagittarius Stream in Gaia DR2 Revealed with the STREAMFINDER Spyglass
Authors: Ibata Rodrigo , Bellazzini Michele , Thomas Guillaume , Malhan Khyati , Martin Nicolas , Famaey Benoit , Siebert Arnaud
Published: March 2020

We present the first full six-dimensional panoramic portrait of the Sagittarius stream, obtained by searching for wide stellar streams in the Gaia DR2 data set with the STREAMFINDER algorithm. We use the kinematic behavior of the sample to devise a selection of Gaia RR Lyrae, providing excellent distance measurements along the stream. The proper motion data are complemented with radial velocities from public surveys. We find that the global morphological and kinematic properties of the Sagittarius stream are still reasonably well reproduced by the simple Law & Majewski model (LM10), although the model overestimates the leading arm and trailing arm distances by up to ∼15%. The sample newly reveals the leading arm of the Sagittarius stream as it passes into very crowded regions of the Galactic disk toward the Galactic anticenter direction. Fortuitously, this part of the stream is almost exactly at the diametrically opposite location from the Galactic center to the progenitor, which should allow an assessment of the influence of dynamical friction and self-gravity in a way that is nearly independent of the underlying Galactic potential model.
Stabilization of Dayside Surface Liquid Water via Tropopause Cold Trapping on Arid Slowly Rotating Tidally Locked Planets
Authors: Ding Feng , Wordsworth Robin D.
Published: March 2020

Terrestrial-type exoplanets orbiting nearby red dwarf stars (M dwarfs) are among the best targets for atmospheric characterization and biosignature searches in the near future. Recent evolutionary studies have suggested that terrestrial planets in the habitable zone of M dwarfs are probably tidally locked and have limited surface water inventories as a result of their host stars’ high early luminosities. Several previous climate simulations of such planets have indicated that their remaining water would be transported to the planet’s permanent nightside and become trapped as surface ice, leaving the dayside devoid of water. Here we use a three-dimensional general circulation model with a water cycle and accurate radiative transfer scheme to investigate the surface water evolution on slowly rotating tidally locked terrestrial planets with limited surface water inventories. We show that there is a competition for water trapping between the nightside surface and the substellar tropopause in this type of climate system. Although under some conditions the surface water remains trapped on the nightside as an ice sheet, in other cases liquid water stabilizes in a circular area in the substellar region as a wetland. Planets with 1 bar N2 and atmospheric CO2 levels greater than 0.1 bar retain stable dayside liquid water, even with very small surface water inventories. Our results reveal the diversity of possible climate states on terrestrial-type exoplanets and highlight the importance of surface liquid water detection techniques for future characterization efforts.
Lung Volume Reduction Surgery in Patients with Heterogenous Emphysema: Selecting Perspective
Authors: Giang Nguyen Truong , Nguyen Ngoc Trung , Nam Nguyen Van , Nhung Nguyen Viet , Thang Ta Ba , Hung Dong Khac , Bac Nguyen Duy , Toi Chu Dinh , Hung Pham Ngoc
Published: March 2020

BACKGROUND: Lung volume reduction surgery (LVRS) was introduced to alleviate clinical conditions in selected patients with heterogenous emphysema. Clarifying the most suitable patients for LVRS remained unclear.
AIM: This study was undertaken to specifically analyze the preoperative factor affecting to LVRS.
METHODS: The prospective study was conducted at 103 Military Hospital between July 2014 and April 2016. Severe heterogenous emphysema patients were selected to participate in the study. The information, spirometry, and body plethysmographic pulmonary function tests in 31 patients who underwent LVRS were compared with postoperative outcomes (changing in FEV1 and CAT scale).
RESULTS: Of the 31 patients, there was statistically significant difference in the outcome of functional capacity, lung function between two groups (FEV1 ≤ 50% and > 50%) (∆FEV1: 22.46 vs 18.32%; p = 0.042. ∆CAT: 6.85 vs 5.07; p = 0.048). Changes of the FEV1 and CAT scale were no statistically significant differences in three groups residual volume. Patients with total lung capacity < 140% had more improved than others (∆FEV1: 23.81 vs 15.1%; p = 0.031).
CONCLUSION: Preoperative spirometry and body plethysmographic pulmonary function tests were useful measures to selected severe heterogenous emphysema patients for LVRS. Patients with FEV1 ≤ 50%, TLC in the range of 100-140% should be selected.
L’extase déchiffrée
Authors: Kaltenbeck Franz
Published: March 2020

Dans son essai sur Proust, Samuel Beckett explique, en 1930, la fonction que l’art a pour l’auteur d’ À la recherche du temps perdu . Proust suppose à l’art la clarté, écrit Beckett. Grâce à cette qualité, l’art peut déchiffrer « l’extase énigmatique » éprouvée par le narrateur de la Recherche quand il contemple « les formes impénétrables » de certains objets. Contrairement à l’esthétique de Schopenhauer, ce ne sont pas des objets extraordinaires qui déclenchent les extases de Proust. Beckett précise néanmoins que « le mystère, l’Idée, l’essence » y sont « prisonniers de la matière ». En relisant Proust et Beckett, nous montrons l’impact de ce débrouillage de l’extase par l’art pour la psychanalyse.
Histoire du taoïsme et des religions chinoises
Authors: Lagerwey John
Published: March 2020

Programme de l’année 2006-2007 : Enquête sur les « dieux-ancêtres » (région hakka, Zhao’an, Huizhou)
Bouddhisme chinois
Authors: Hureau Sylvie
Published: March 2020

Programme de l’année 2006-2007 : I. Les rites bouddhiques dans la culture chinoise : les assemblées de jeûne — II. Textes et pratiques rituelles du bouddhisme chinois (iie-vie siècles)
Religion de l’Égypte ancienne
Authors: Zivie-Coche Christiane
Published: March 2020

Programme de l’année 2006-2007 : I. L’Ogdoade : élaboration et évolution d’une cosmogonie, du Nouvel Empire à l’époque ptolémaïque (suite) — II. Géographie religieuse : une approche du delta oriental
Religions et institutions en Grèce ancienne
Authors: de Polignac François
Published: March 2020

Programme de l’année 2006-2007 : Constructions et interprétations cultuelles de l’espace aux confins entre Béotie et Attique antique
Institutions religieuses des cités grecques
Authors: Georgoudi Stella
Published: March 2020

Programme de l’année 2004-2005 : La question controversée du sacrifice humain et les oracles grecs  — Programme de l’année 2005-2006 : Dieux « olympiens », « ouraniens », « chthoniens » : nouvelles perspectives — Programme de l’année 2006-2007 : Organisation des sanctuaires et activité oraculaire en Béotie antique
Nouvelles recherches sur les mystères de Mithra
Authors: Mastrocinque Attilio
Published: March 2020

Programme de l’année 2006-2007 : I. Les mystères des Romains — II. Mithra et l’orphisme. Mithra et les dieux hypercosmiques
Deux systèmes religieux dans l’Ancien Testament : de la concurrence à la convergence
Authors: Gonçalves Francolino J.
Published: March 2020

Programme de l’année 2006-2007 : Introduction — I. Le yahvisme fondé sur le mythe de la création — II. Le yahvisme fondé sur l’histoire d’Israël avec son Dieu — III. La fusion des deux yahvismes
La Bible des Septante
Authors: Dogniez Cécile
Published: March 2020

Programme de l’année 2006-2007 : Lecture de textes prophétiques : études linguistiques et histoire du texte
Les dilemmes de la citoyenneté européenne. Vers une citoyenneté cosmopolite
Authors: Lutz Helma
Published: March 2020

Programme de l’année 2006-2007 : I. Les dilemmes de la citoyenneté européenne : genre, migrations et inégalités sociales — II. La citoyenneté cosmopolite
Techniques de la recherche en histoire moderne et contemporaine
Authors: Guillon Hélène
Published: March 2020

Programme de l’année 2005-2006 : Ce séminaire a réuni des étudiants inscrits en Master II et en début de doctorat. Il avait pour but de fournir à ces étudiants de Sciences religieuses des outils méthodologiques leur permettant d’aborder la recherche historique […]
Histoire et traditions des christianismes orientaux
Authors: Jullien Florence
Published: March 2020

Programme de l’année 2006-2007 : Le christianisme en Iran sassanide à l’épreuve des déportations (fin)
Histoire des chrétiens d’Orient (xvie-xxie siècle)
Authors: Heyberger Bernard
Published: March 2020

Programme de l’année 2006-2007 : L’étude des parcours de « médiateurs », de ces chrétiens qui ont circulé entre l’Orient et l’Occident, ou qui, sans voyager, ont été entre les deux mondes de par leur situation : chrétiens gyrovagues et quêteurs d’aumônes dans l’Europe catholique […]
La vie religieuse sous les Paléologues
Authors: Congourdeau Marie-Hélène
Published: March 2020

Programme de l’année 2006-2007 : Recherches sur Nicolas Cabasilas et son époque
Histoire de l’exégèse chrétienne au Moyen Âge
Authors: Dahan Gilbert
Published: March 2020

Programme de l’année 2006-2007 : I. Le Décalogue dans l’exégèse et la théologie, xiie‑xiiie siècles — II. L’exégèse du récit des pèlerins d’Emmaüs (Luc 24, 12‑35)
Arts du langage et théologie au Moyen Âge
Authors: Rosier‑Catach Irène
Published: March 2020

Programme de l’année 2006-2007 : I. La locution angelica selon Gilles de Rome — II. Les Glosulae sur Priscien, Guillaume de Champeaux, Abélard : discussions sur la nature de la voix
Exégèse et théologie de l’islam shiʼite
Authors: Amir-Moezzi Mohammad Ali
Published: March 2020

Programme de l’année 2006-2007 : Théorie de la connaissance dans le shiʼisme ancien (suite)
Mystique musulmane
Authors: Lory Pierre
Published: March 2020

Programme de l’année 2006-2007 : L’eschatologie dans les commentaires mystiques du Coran
Le politique entre vie et mort
Authors: Revault d’Allonnes Myriam
Published: March 2020

Programme de l’année 2006-2007 : « Le thème des conférences a poursuivi le travail des années précédentes, mené autour de la constitution affective du politique. En réfléchissant aujourd’hui sur sa propre spécificité mais aussi sur les conditions de l’actualité, la philosophie politique ne saurait manquer d’intégrer une analyse de la dynamique affective qui sous-tend la constitution des communautés politiques. […] »
Recherches sur les courants ésotériques dans l’Europe moderne et contemporaine
Authors: Faivre Antoine
Published: March 2020

Programme de l’année 2006-2007 : I. Approches méthodologiques et constructions théoriques (depuis 1964 environ) portant sur l’objet de la spécialité — II. Les illustrations des œuvres de Böhme par Michael Andreae (1682) — III. Nouvelles enquêtes portant sur l’« éloquence magique »
Épistémologie et historiographie des sciences des religions
Authors: Koch Piettre Renée
Published: March 2020

Programme de l’année 2006-2007 : I. Les polythéismes. Sommes historiographiques — II. Collections d’oracles, collections de sagesse dans le monde grec ancien
« Entendre ce qui est sans voix » – le continent noir de la psychanalyse
Authors: Ginésy Pierre
Published: March 2020

Programme de l’année 2006-2007 : « Cette conférence se propose d’interroger les impasses actuelles de la psychanalyse par l’interrogation de ses textes classiques, et, au‑delà, par le recours aux travaux d’épistémologie contemporaine, à l’ethnographie et à l’anthropologie historique. […] »
Origines du christianisme
Authors: Mimouni Simon C.
Published: March 2020

Cette année, a été poursuivi le programme de recherche sur « l’histoire de la communauté chrétienne / nazoréenne de Jérusalem des origines à 135 », commencé en 2005-2006.
Religions de l’Afrique Noire
Authors: Journet-Diallo Odile
Published: March 2020

Programme de l’année 2006-2007 : 1.  Les paradoxes du rite kañalen — 2. Élargissements
Religions de l’Asie septentrionale
Authors: Hamayon Roberte
Published: March 2020

Programme de l’année 2006-2007 : I. Revue de travaux récents — II. De nouveau, sur la série sémantique de la « chance » — III. La structuration métaphorique de la structure religieuse — Exposés
Protein Quality Control in Neurodegeneration and Neuroprotection
Authors: Akhter Yasmeena , Nabi Jahangir , Hamid Hinna , Tabassum Nahida , Pottoo Faheem Hyder , Sharma Aashish
Published: March 2020

Proteostasis is essential for regulating the integrity of the proteome. Disruption of proteostasis under some rigorous conditions leads to the aggregation and accumulation of misfolded toxic proteins, which plays a central role in the pathogenesis of protein conformational disorders. The protein quality control (PQC) system serves as a multi-level security system to shield cells from abnormal proteins. The intrinsic PQC systems maintaining proteostasis include the ubiquitin-proteasome system (UPS), chaperon-mediated autophagy (CMA), and autophagy-lysosome pathway (ALP) that serve to target misfolded proteins for unfolding, refolding, or degradation. Alterations of PQC systems in neurons have been implicated in the pathogenesis of various neurodegenerative disorders. This chapter provides an overview of PQC pathways to set a framework for discussion of the role of PQC in neurodegenerative disorders. Additionally, various pharmacological approaches targeting PQC are summarized.
Molecular Interactions of α-Synuclein, Mitochondria, and Cellular Degradation Pathways in Parkinson's Disease
Authors: Verma Mansi , Basu Sujata , Singh Manisha , R. Rachana , Kaur Simrat , Goel Neha
Published: March 2020

Parkinson's disease (PD) has been reported to be the most common neurodegenerative diseases all over the world. Several proteins are associated and responsible for causing PD. One such protein is α-synuclein. This chapter discusses the role of α-synuclein in PD. Various genetic and epigenetic factors, which cause structural and functional changes for α-synuclein, have been described. Several molecular mechanisms, which are involved in regulating mitochondrial and lysosomal related pathways and are linked to α-synuclein, have been discussed in detail. The knowledge gathered is further discussed in terms of using α-synuclein as a diagnostic marker for PD and as a novel therapeutic target for the same.
Multifarious Role of BAG3 in Neurodegenerative Disorders
Authors: Basu Sujata , Singh Manisha , Verma Mansi , R. Rachana
Published: March 2020

The glial cells along with cells of hematopoietic origin and microvascular endothelia work together to maintain the normal development and/or functioning of the nervous system. Disruption in functional coordination among these cells interrupts the efficiency of the nervous system, leading to neurodegeneration. Various proteins in the nerve cells maintain the normal signaling mechanism with these cells and throughout the body. Structural/functional disorganization of these proteins causes neurodegenerative disorders. The molecular mechanisms involved in these phenomena are yet to be explored extensively from therapeutic perspectives. Through this chapter, the authors have elaborated on less known protein Bcl-2 associated athanogene 3 (BAG3) involved in neurodegeneration. They have explored BAG3 protein and its role in neurodegeneration, protein homeostasis, its mechanism of action, its uses as a drug target, and its uses as a possible diagnostic marker of neurodegeneration.
Molecular Chaperones in Neurodegeneration
Authors: Pandey Mukesh , Nabi Jahangir , Tabassum Nahida , Pottoo Faheem Hyder , Khatik Renuka , Ahmad Niyaz
Published: March 2020

Cellular chaperones are essential players to this protein quality control network that functions to prevent protein misfolding, refold misfolded proteins, or degrade them, thereby maintaining neuronal proteostasis. Moreover, overexpression of cellular chaperones is considered to inhibit protein aggregation and apoptosis in various experimental models of neurodegeneration. Alterations or downregulation of chaperone machinery by age-related decline, molecular crowding, or genetic mutations are regarded as key pathological hallmarks of neurodegenerative disorders like Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS), Huntington's disease (HD), and Prion diseases. Therefore, chaperones may serve as potential therapeutic targets in these diseases. This chapter presents a generalized view of misfolding and aggregation of proteins in neurodegeneration and then critically analyses some of the known cellular chaperones and their role in several neurodegenerative disorders.
Outdoor Solutions for the Seasonal Concentration of Tourism Demand in Northern Portugal
Authors: Fernandes Paula Odete , Nunes Alcina Maria , Veloso Cláudia Miranda , Santos Eleonora , Ferreira Fernanda A. , Fonseca Manuel José Serra
Published: March 2020

Measures that address the seasonality, one of the identified overtourism direct causes, allow making a critical reflection on the application of control policies and monitoring regional measures crucial on a sector with such importance at the regional development analysis. The measures should stimulate or reduce tourism demand during low or peak seasons, respectively, generating a better distribution of tourism flows and eliminating potential overtourism situations. Therefore, this chapter focuses on the development of a Gini Index to analyse the distribution of the seasonality in northern Portugal and through it control current public measures in practice and suggest the implementation of different and more effective policy measures. For instance, the ones that make a clear bet on outdoor tourism activities. It will be used in the Gini Index, by the tourists' market of origin measured by the overnight stays in hotel establishments. The results showed the high seasonal concentration of tourist flows.
Forging University Social Responsibility Through Community Engagement at Higher Education
Authors: Tshishonga Ndwakhulu Stephen
Published: March 2020

This chapter interrogates the notion of community engagement or service learning. The chapter argues that universities pay lip service to community engagement to the detriment of teaching and research functionaries. Most prestige universities operate on the belief that it is only research that matters; hence, research is prioritized. Universities and their staff have adopted an ‘ivory tower' attitude. This modus operandi negates the reality that reliable knowledge could be produced through responsible community engagement and can become the source of empirical data that can be used for teaching and shared through publications. For universities to impact transformational change within and in their surroundings, community engagement should be elevated to equal teaching and learning.
Using an Artificial Neural Network to Improve Email Security
Authors: Maki Mohamed Abdulhussain Ali Madan , Subramanian Suresh
Published: March 2020

Email is one of the most widely used features of internet, and it is the most convenient method of transferring messages electronically. However, email productivity has been decreased due to phishing attacks, spam emails, and viruses. Recently, filtering the email flow is a challenging task for researchers due to techniques that spammers used to avoid spam detection. This research proposes an email spam filtering system that filters the spam emails using artificial back propagation neural network (BPNN) technique. Enron1 dataset was used, and after the preprocessing, TF-IDF algorithm was used to extract features and convert them into frequency. To select best features, mutual information technique has been applied. Performance of classifiers were measured using BoW, n-gram, and chi-squared methods. BPNN model was compared with Naïve Bayes and support vector machine based on accuracy, precision, recall, and f1-score. The results show that the proposed email spam system achieved 98.6% accuracy with cross-validation.