bluuebunny/crossref_metadata_2025 huggingface dataset:
Pengaruh Kitosan Terhadap Jumlah Osteoklas dan Osteoblas Pada Tikus Galur Wistar Model Menopause
Authors: Nur Muhammad
Published: November 2017

Chitosan is one of the most abundant and dispersed polymers in nature. It has a rapid healing effect for tissues and has an effect on bone remodeling. The purpose of this study was to prove that giving chitosan influenced the decrease of osteoclast number and increasing number of osteoblasts in female mice of wistar strain of ovariectomy menopause model.This study used a posttest only control group design. The total sample of 30 rats divided into three groups was randomized, osteoporosis was made with the menopausal model which was performed ovariectomy in the positive control group and the treatment group then in the treatment group was given chitosan extract of single dose of 45 mg / day via Nasogastric Tube (NGT). K1 was a negative control group (without ovariectomy and without chitosan), K2 was a positive control group (with no chitosan ovariectomy), K3 was the treatment group (ovariectomy and chitosan 45 mg / day).The results showed significant differences in the number of osteoblasts between K1 and K3, K2 with K3, and no significant differences were found in the K1 group with K2. While the number of osteoclasts showed that there were significant differences in K1 group with K2 and no significant difference was found in K1 group with K3, K2 with K3.Conclusions in this study showed that 45 mg / day of chitosan doses could significantly increase osteoblast counts in menopause female white rats and decrease the number of osteoclasts performed by ovariectomy with chitosan administration.
Efektifitas Pemberian Diet Beras Merah Dalam Menurunkan Kadar Gula Darah Pada Penderita Diabetes Mellitus Di Puskesmas Pademawu Pamekasan
Authors: Kuszairi Kuszairi
Published: November 2017

Diabetes mellitus (DM) is a disease in which blood glucose levels are high because the body can not release or use insulins sufficiently. Treatment of diabetes includes weight control, exercise and diet. One way of diet is to use brown rice. The purpose of this study to determine the effectiveness of red rice diet in lowering blood sugar levels in patients with DM. The design of this research used Quasy-Experiment research design with Simple Random Sampling method. The sample used was 16 respondents from population of 76 DM patients who performed outpatient at Puskesmas Palengaan in June 2008. Data collection was done by observing the blood sugar level before and after intervention of red rice diet using GlucoDr tool. After being tabulated, the existing data were analyzed by using Paired Sample T Test with a significance level of 0.05. The results of statistical tests obtained that H0 rejected and H1 accepted, meaning red rice diet is effective against the decrease in blood sugar levels DM patients with a value of t count of 7.202 with a significant level of 0.000. Given the results of this study proves that the red rice diet can reduce blood sugar levels of DM patients so the need for awareness of DM patients to implement a red rice diet in order to reduce the risk of complications from DM.
The Relationship Between Chaebol And Firm Value Using Bayesian Network
Authors: Sun Eun-Jung , Park Sung-Jin
Published: November 2017

The purpose of this study is to analyze the effects of being a chaebol company, the biggest company characteristic variable, on firm value. It tries to overcome the limitation of multiple regression analysis mostly used in preceding research. That is, as multiple regression analysis assumes uniform linearity between dependent and independent variables, it could not reflect the diverse types of the real world. Thus, based on being a chaebol company and financial information, company characteristic variables influencing firm value, this study derives causal relationships existing between them. The results could help managers and various accounting information users in their decision-making by providing them with information of what company characteristics would directly or indirectly influence firm value. To this end, this study utilizes Bayesian Network and attempts Markov Blanket. In the end, all the analysis methods used in this study not only provides significant results, but also raises its practical value by offering information of diverse situations that could occur in the real world.
Product Market Competition And Analysts’ Forecasting Properties: Evidence From Korea
Authors: Lee Jaehong , Mo Kyoungwon
Published: November 2017

In this paper, we examine the association between product market competition and financial analysts’ forecasting properties in a sample of 76,621 analyst-firm-year observations in South Korea between 2000 and 2014. Using the Herfindahl–Hirschman Index to proxy for product market competition, we document that financial analysts are likely to issue less accurate and more optimistic forecasts in highly competitive product markets. In addition, we find that analysts’ reports show more optimism in stock recommendations in firms with high market competition.
How Do Biotech Cluster Firms Catch Knowledge Spillovers? The Strong Impact Of The Institutional Mechanisms
Authors: Boufaden Najoua
Published: November 2017

This paper deals with the nature of the mechanisms supporting knowledge spillovers diffusion in high-tech clusters. The literature in the geography of innovation focuses on the existence of local knowledge spillovers, which are enhanced by geographic and technological proximity. However, the mechanisms explaining the diffusion of spillovers are not well understood. If knowledge spillovers exist, how does this knowledge diffuse among the actors? Do spillovers spread in the air, as suggested by Marshall? Or, are there mechanisms that explain their dissemination?

Based on a firm survey data base and an original methodology, the paper explores the determinants of knowledge spillovers. The paper has twofold purposes; the first one is to determine the main mechanisms within a region enabling the diffusion of spillovers. The second objective is measuring the impact of these main mechanisms on firm’s innovation performance, indicating which of these mechanisms are more effective in transporting knowledge spillovers between agents. The results show new empirical evidences on the role played by institutions[1] in the dissemination of externalities. However, informal mechanisms, such as face-to-face contacts commonly stressed in the literature, have no significant and negative effects in this case.

[1] Institutions are defined here as a kind of structures that matter in structuring social interactions (Hogdson, 2006). Institutions can enable or constraint choices and actions. So it can enhance agent behaviors and actions that otherwise would not exist. According to this definition, formal institutions supporting R&D and innovation activities of SMEs in the biotech industry can enable or constraint actions of these firms regarding accessibility to critical resources available in a given region such as knowledge, information, finance, etc. Finally, we can assume that Institutions structures can explain variation in regional innovation performance.
The Effect Of Nostalgia On Service Failure
Authors: Jeon Jin A , Kim Ja-Yeon
Published: November 2017

Nostalgia induced by savoring precious past experience helps a person feel loved and protected and may help them cope with loneliness. Generally, these positive, prosocial functions, which nostalgia provides, are derived from the content of the memories. However, recent research shows that the process of recalling nostalgic memories could have an important, but different impact on consumers' behavior.

When people face nostalgia through the recollection of positive experience and become aware of its non-repeatability, they seek to enjoy and prolong the experience. Due to the motivation to savor nostalgic experiences, people are likely to be more tolerant of waiting. To this extent, the inclination to reminisce about past experiences motivates people to be more accepting of, thus less dissatisfied with service failure.

Unlike other research focusing on social functions of nostalgia, we examine the effect of nostalgia to a particular service failure: delayed shipping. Nowadays, on-line retailers that use a delivery service is commonplace. Therefore, we believe our research will give critical implications about the effects of nostalgia on service failure. We theorize that nostalgia could have a positive effect on consumer patience, especially for delayed shipping, and the distance to a nostalgic memory affects consumer patience and dissatisfaction. Two studies have confirmed these effects.
Does Board Characteristics Constrain Real Earnings Management? Evidence From Korea
Authors: Oh Hyun Min , Jeon Heung Joo
Published: November 2017

This study empirically analyzes the effect of board characteristics on real earnings management, which is measured by using three proxies including abnormal cash flows from operations, abnormal discretionary expenses, and abnormal production costs. Specifically, we will investigate how board independence (or board size) affects real earnings management. Additionally, we will investigate the relation between the board characteristics and real earnings management according to before K-IFRS mandatory adoption or after K-IFRS mandatory adoption.

The empirical results of this study are as follows. First, the relation between board independence (board size) and the absolute value of abnormal cash flows from operations is statistically significant and positive (+). Second, the relation between board independence (board size) and the absolute value of abnormal production costs is statistically significant and positive (+). Third, the relation between board independence (board size) and the absolute value of abnormal discretionary expenses is statistically significant and positive (+). These findings present that the board independence (or board size) does not constrain real earnings management. Thus, these mean that board independence (or board size) does not work as a mechanism to reduce real earnings management.

This study contributes to accounting research as it directly tests the relation between the board characteristics and real earnings management in Korea, providing empirical support that a board independence (board size) does not constrain real earnings management as effectively as it constrains accrual earnings management.
Earnings Predictability And Broker-Analysts’ Earnings Forecast Bias
Authors: Eames Michael , Glover Steven
Published: November 2017

Scholars have reasoned that analysts issue optimistic forecasts to improve their access to managers’ private information when earnings are unpredictable. While this requires a managerial preference for analyst forecast optimism, the observed walk-down of analyst expectations to beatable forecasts is consistent with a managerial preference for pessimism in short-horizon forecasts. Using data from various sample periods, alternative model specifications, and various measures of earnings unpredictability, we find that pessimism, not optimism, in short-horizon forecasts is associated with increasingly unpredictable earnings. Our results suggest that firms can more effectively manage analysts’ earnings expectations downward when earnings are relatively unpredictable.
A Study On Accounting Conservatism Of Capital-Raising Corporations
Authors: Hong Soonwook
Published: November 2017

Various factors affect conservative accounting of corporations. Most of all, this paper focuses on the factor of corporate capital raising. One of the important roles of conservatism is that companies conduct conservative accounting to cut the agency costs due to information asymmetry. Managers may desire excellent management performance and stable financial condition. Depending on circumstances, they seek to improve management performance and financial condition by choosing a proper accounting method. That is, they have incentives to carry out less conservative accounting. Companies that raise capital may have stronger incentives to take such an accounting method. On the contrary, if a capital market monitoring system works properly, corporations would conduct conservative accounting to reduce the agency costs. The results of the empirical analysis reveals that the Korean listed companies raising capital choose less conservative accounting than those that do not raise capital. This indicates companies without financing conduct conservative accounting more than those with.
Effect of Expenditures on Education, Human Capital Development and Economic Growth in Nigeria
Authors: Lucas Elumah , Shobayo Peter
Published: November 2017

Earlier studies on economic growth asserts that economic prosperity and functioning of a nation depends on its physical and human capital stock in form of knowledge acquired and an agent of national development in all countries of the world. Therefore, the need to examine the effect of expenditures on education, human capital development on economic growth in Nigeria. This study focuses on public expenditures on the education with a view to ascertain the relative commitments of the governments to this sector.

 

This study covers the period of 1970-2015, employing an ex-post facto research design using time series data. The data used for this study are obtained mainly from secondary data which is quantitative in nature. The study employs descriptive statistics to assess the contributions of government expenditure on education, government expenditure on health, tertiary school enrolment, secondary school enrollment, primary school enrolment on gross domestic product. Also, Unit Root Test is conducted on the series to ascertain if they are stationary while co-integration test follows suit, to also ascertain the long run relationship between expenditure on education and human capital development on economic growth. The Johansen Cointegration test and Error Correction Mechanism estimated model found that that there is no significant effect of expenditure on education and human capital development on economic growth in Nigeria.

 
Ending Religious Extremism in Northern Nigeria: A Study of Elnathan John’s Born on a Tuesday
Authors: Dauda Susan
Published: November 2017

Fundamentalism has been defined as an unwavering faith to a religious system. Although it could be applied to adherents of any religion, today it is mostly associated with Islam. Islam is said to have arrived Nigeria in the 11th century through the activities of mostly traders but it eventually took root and spread through the Fulani jihad of Usman Dan Fodio and the establishment of the Sokoto caliphate. From the late 1970s several reform movements have taken place but the most violent have been that of Maitatsine and currently the Boko Haram insurgency. Born on a Tuesday is a story about religious fundamentalism told by Dantala an almajiri. In telling the story we see the various issues that create an atmosphere in which fundamentalism thrives. Gladly in stating the issues we also note the solutions. This paper therefore discusses the problem of fundamentalism and highlights the solutions as evident in the book.
Are Audits of Financial Statements Born Unequal?
Authors: Tran Manh Dung , Doan Van Anh , Bui Thi Thuy , Nguyen Manh Cuong
Published: November 2017

Audit is getting more and more importance in assuring the reliability of financial information including financial statements for all parties. Commonly, quality of an audit is viewed as probability that financial reports are free from material irregularities. In the previous literature, there is a positive relationship between size of audit firm and audit quality that has long been understood. This has resulted in many publications to gather evidence of differential audit quality relating to audit firm size. In consequence, the conclusion has been focused that bigger audit firms produce higher audit quality than smaller ones. However, the collapse of many big international audit firms, typically Arthur Andersen has reduced the statement that large audit firms have higher audit quality than small ones. Therefore, this study looks into audit quality basing on the extent of compliance with disclosure requirements pertaining to goodwill impairment of large listed firms in Hong Kong context in the second year transition to IFRS. We found that audit firm identity appears to be a substantial variation, in which compliance levels changed significantly among auditors in the context of Hong Kong.
Effelsberg Monitoring of a Sample of RadioAstron Blazars
Authors: Liu Jun , Krichbaum Thomas P. , Liu Xiang , Kraus Alex , Bignall Hayley , Kovalev Yuri Y. , Sokolovsky Kirill V. , Zensus J. Anton
Published: November 2017

The launch of the RadioAstron space radio telescope provides a unique opportunity to study the extreme high brightness temperature of Active Galactic Nuclei (AGNs) with unprecedented long baselines of up to 28 Earth diameters. A coordinated ground-based flux density monitoring of RadioAstron targets is essential to determine the effect of interstellar scintillation (ISS) on the Space Very Long Baseline Interferometry (SVLBI) visibilities. Moreover, a combination/comparison of scintillation with SVLBI observations is expected to reveal the relative influence of source brightness temperature, compactness, and properties of the interstellar medium on the observed variability at centimeter wavelengths. In 2014 we started a RadioAstron target triggered flux monitoring with the Effelsberg 100-m radio telescope in support of this SVLBI mission. A total of 112 targets were observed during the five-session monitoring performed so far. In this paper we present a statistical study on the short-term flux density variability of the sample, which is focused on the variability characteristics and derived physical properties of the observed sources.
Anti-Osteoporotic Effects of Kukoamine B in Osteoblast and Osteoclast Cells and Ovariectomized Mice
Authors: Park Eunkuk , Kim Jeonghyun , Kim Mun-Chang , Yeo Subin , Kim Jieun , Choi Chun Whan , Jin Hyun-Seok , Lee Sang Woo , Li Wan Yi , Lee Ji-Won , Park Jin-Hyok , Huh Dam , Jeong Seon-Yong
Published: November 2017

Osteoporosis is an abnormal bone remodeling condition characterized by decreased bone density, which leads to high risks of broken bones. Previous studies have demonstrated that Lycii Radicis Cortex (LRC) extract inhibits bone loss in ovariectomized (OVX) mice by enhancing the osteoblast differentiation. A bioactive compound, Kukoamine B (KB), was identified from a fractionation of LRC extract as a candidate component responsible for an anti-osteoporotic effect. This study investigated the anti-osteoporotic effects of KB using in vitro and in vivo osteoporosis models. KB treatment significantly increased the osteoblastic differentiation and mineralized nodule formation of osteoblastic MC3T3-E1 cells, while it significantly decreased the osteoclast differentiation of primary-cultured monocytes derived from mouse bone marrow. The effects of KB on osteoblastic and osteoclastic differentiations under more physiological conditions were also examined. In the co-culture of MC3T3-E1 cells and monocytes, KB promoted osteoblast differentiation but did not affect osteoclast differentiation. For the in vivo experiments, KB significantly inhibited OVX-induced bone mineral density loss and restored the impaired bone structural properties in osteoporosis model mice. These results suggest that KB may be a potential therapeutic candidate for the treatment of osteoporosis.
4-Thiazolidinone Derivatives as MMP Inhibitors in Tissue Damage: Synthesis, Biological Evaluation and Docking Studies
Authors: Incerti Matteo , Crascì Lucia , Vicini Paola , Aki Esin , Yalcin Ismail , Ertan-bolelli Tugba , Cardile Venera , Graziano Adriana , Panico Annamaria
Published: November 2017

Nine 2-(1,2-benzothiazol-3-yl)-N-(4-oxo-2-phenyl-1,3-thiazolidin-3-yl) propanamides were designed and synthesized, combining benzisothiazole and 4-thiazolidinone in one frame. The aim of the study was to verify their effectiveness to contrast  the inflammatory/oxidative  process  in which  free oxygen and nitrite (ROS and RNS) radicals, advanced glycation products (AGEs), inflammatory cytokines and matrix metalloproteinases (MMPs) are involved. Docking studies of all the compounds were performed in order to explore their binding mode at the MMP-9 protein.  An appreciable anti-inflammatory/wound healing effects of the tested compounds was highlighted. Derivative 23, bearing a 4-carboxyphenyl substituent at C2 of the 4-thiazolidinone ring, exhibited the highest activity, being able to inhibit MMP-9 at nanomolar level  (IC50  = 40 nM).
HUBUNGAN POLA ASUH MAKAN DENGAN STATUS GIZI USIA ANAK SEKOLAH DI SDN TELUK PUCUNG VI BEKASI
Authors: Indriyani Rita Anugra
Published: November 2017

Penelitian  ini  bertujuan  untuk  mengetahui  hubungan  pola  makan  dengan  status  gizi  usia  anak sekolah  di  sekolah  dasar  negeri  Teluk  Pucung  VI,  Bekasi.  Metode  penelitian  yang  dilakukan adalah pendekatan cross sectional. Sampel dari penelitian ini adalah murid kelas 4 dan 5 sekolah dasar  Teluk  Pucung  VI,  Bekasi  dengan  174  jumlah  sampel  dari  murid -murid    dan  (obstaind) adalah  67  murid,  teknik  pengumpulan  sampel  menggunakan  sampel  acak  sederhana.  Hipotesi dari penelitian menggunakan analisis (binary logistic regression). Hasil dari pengolahan data menunjukkan  bahwa  terdapat  hubungan  yang  siginifikan  antara memelihara  pola makan dengan status  gizi  anak.  Data  ini  signifikan  karena  nilai  p 0,006 < 0,05. Contoh nilai  (B) pada variabel pola  asuh  makan  1,145  membuktikan  bahwa  semakin  meningkat  atau semakin baik pola asuh makan maka status gizi anak untuk menjadi lebih normal akan meningkat  sebesar 1,145 kali
ANALISIS PENGEMBALIAN KREDIT KETAHANAN PANGANDAN ENERGI (KKP-E) PETANI PADIDI KABUPATEN KUDUS
Authors: Pertiwi Widhi Netraning , Irham Irham , Masyhuri Masyhuri
Published: November 2017

Tujuan penelitian ini adalah untuk mengetahui : (1) tingkat pengembalian KKP-E yang sudah dibayarkan oleh petani padi dan untuk mengetahui tingkat kelancaran serta kemampuan pengembalian KKP-E dan (2) faktor-faktor yang mempengaruhi tingkat pengembalian KKP-E oleh petani padi di Kabupaten Kudus. Metode dasar yang digunakan adalah analisis deskriptif. Pengambilan sampel menggunakan metode sensus. Jumlah sampel yang digunakan dalam penelitian ini sebanyak 31 responden petani padi yang mengambil KKP-E yang telah jatuh tempo pengembalian kredit. Tingkat pengembalian KKP-E yang diambil oleh petani padi dianalisis menggunakan analisis deskriptif yang diperoleh dari analisis tabel, dimana jumlah pengembalian ini yang akan digunakan sebagai variabledependent (Y) yang diregresikan dengan variable independent (X) merupakan faktor-faktor yang menentukan keberhasilan pengembalian KKP-E, untuk menguji kebenaran hipotesis tingkat pengembalian KKP-E oleh petani padi digunakan analisis uji t yaitu Paired t Test. Untuk menganalisis faktor-faktor yang mempengaruhi Keberhasilan Pengembalian KKP-E oleh petani padi digunakan Metode Regresi Linier Berganda.Hasil penelitian menunjukkan bahwa tingkat pengembalian KKP-E di Kabupaten Kudus dikategorikan lancar dan tepat waktu dengan persentase tingkat tunggakan adalah sebesar 8%, dan faktor-faktor yang mempengaruhi keberhasilan pengembalian KKP-E adalah jumlah pinjaman, lama usahatani, luas lahan, serta umur. 
Experimental and Theoretical Study of Water and Solute Transport in Organic-Rich Carbonate Mudrocks
Authors: Padin A.. , Torcuk M. A. , Katsuki D.. , Kazemi H.. , Tutuncu A. N.
Published: November 2017

The objective of this research is to determine the physicochemical processes underlying water and solute transport in organic-rich source rocks. To achieve this goal, a custom-designed experimental apparatus was constructed to conduct flow tests, founded on a high-pressure triaxial assembly. The apparatus is capable of maintaining core samples at reservoir pressure, temperature, and confining stress. We conducted several 120-day low-salinity osmotic tests in low-clay, organic-rich Eagle Ford carbonate-shale samples. Test results showed gradual, slow increase of pressure within the samples. Because this pressure behavior could not be explained properly with classical models, we formulated a mass-transport mathematical model that relies on fundamental chemical osmosis principles driving low-salinity brine into high-salinity core samples.

Our mathematical model was articulated to simulate flow into the core as a 3D porous medium rather than transport across a thin, molecule-selective membrane. The model is dependent on the following principles: The low-salinity brine selectively enters the pores by diffusion mass transport, and the pre-existing, ionized dissolved salt molecules within the core are restrained by internal electrostatic forces to counterdiffuse in the direction opposite to that of the low-salinity-brine molecules entering the pore network. Critical model input data, such as permeability, porosity, and rock compressibility, were obtained from flow experiments on twin cores, and the diffusion coefficient was chosen by history matching. The strengths of the numerical simulation include reliance on mass-transport fundamental principles; not requiring the use of an ambiguously defined membrane-efficiency term; and relying on chemical-potential gradient as the driving force for the low-salinity brine to enter the high-salinity core, generating osmotic pressure within the pore network. The latter implies that osmotic pressure is the consequence of water entering the cores, not the cause. Results of this research have provided a more plausible explanation of pore-scale mass transport in organic-rich shales, and provide useful insights for design of effective enhanced-oil-recovery (EOR) processes.
Application of Low Salinity Water Flooding for Light Paraffinic Crude Oil Reservoir
Authors: Kakati A.. , Jha N. K. , Kumar G.. , Sangwai J. S.
Published: November 2017

Low salinity water flooding is an emerging technology in the field of enhanced oil recovery in recent years. Laboratory investigations and field trials have been done for different reservoirs worldwide to evaluate the performance of this new technique. The majority of the published literature reported positive results for relatively heavy asphaltic rich crude oil. Present work investigates the potential of low salinity water flooding for light oil reservoirs.

The effect of brine salinity and composition on interfacial tension and wettability has been investigated experimentally using crude oil sample from an Indian crude oil reservoir. Interfacial tension between crude oil and different brine solutions were measured using Wilhelmy plate method. The effect of brine composition on wettability is accessed through contact angle measurements using a custom built goniometer on a quartz substrate. Brine solutions of different compositions were prepared by dissolving monovalent and divalent salts in deionized water. Crude oil has been well characterised for its chemical and physical properties including IR spectroscopy. Surface characteristics and composition of the quartz plate, used for contact angle measurements is determined using scanning electron microscopy and electron dispersive X-ray spectroscopy. All the experiments were done under a high-temperature condition which is close to most of the typical petroleum reservoirs. The results of this paper shows that reduction in brine salinity has a significant effect on both crude oil-water interfacial tension and reservoir wettability for light paraffinic oil reservoirs. The oil-water interfacial tension can be decreased with lowering brine salinity. Interfacial tension results also show that higher divalent ion concentration has no significant impact on interfacial tension reduction for paraffinic crude oil. It was observed from contact angle measurements that reduction of brine salinity can significantly affect reservoir wettability from oil wet to water wet condition. But, under extremely low salinity condition, this trend is reversed and become more oil wet. The interfacial tension is also observed to increase slightly at a very low ionic concentration.

In the literature, most of the low salinity investigations were performed on relatively heavy and medium gravity crude oil having significant resin and asphaltene content. Interaction of asphaltene and resin with ions at oil water interface is related to recovery improvement in most of the low salinity literature. But, this study shows that low salinity or smart water could be a potential EOR method for light oil reservoirs with more paraffinic content.
COST-EFFECTIVENESS OF SAILCLOTH SELECTION FOR DIFFERENT CLASSES, TYPES AND SPECIES OF SAILING BOATS
Authors: Yeroshkina Svitlana
Published: November 2017

Results over of theoretical analysis for the selection of corresponding basic material of sail clothes fabric for a different classes, types and views of sailing boats are given in the article.

Sailing boats needs the proper of yachting equipment, that goes both with the manipulation of boats and rigging (in accordance of views, classes and types of sailing boats). The material for sailing is elected by participants of competitions depending of the area of navigation, the strength of wind, the whole distances and boat’s possibilities, coming from technical criteria and parameters of the boats.

Full analysis of economic efficiency is conducted and price politics of different material’s types for sails in accordance with its chemical composition is analyzed. The most effective type of factory fabric is certain for sewing of sails for racing boats. For a deep scientific analysis and practical realization of the investigated process an accent is done on the exposure of the most popular sailing sailcloth materials used only on the famous world regattas.

These results are very important and needed foremost for the first-class skippers of modern world racing boats, to identify most practical and super persistent to the wind, the sun, salt water materials that use in sewing of racing sails. Necessary analyses and descriptions of scientific article concerning sewing of racing sails also will be useful to the yachtsmen that only begin the way in the world of cruise yachting and sporting yachting races. Importance of faithful direction at the choice of material for sails is done not only for the decision element of victories in races and regattas, but also for an answer on many questions, constrained concerning speed of boat, norm of coverage of sails and, in the end, with maneuverability, boat speed.
DETERMINATION OF FORMAL SIGNS FOR INDICATORS OF EFFICIENCY EVALUATION OF CONTROLLED SYSTEMS OPERATIONS
Authors: Serdiuk Olga
Published: November 2017

Research connected with studying of efficiency assessment possibility of system operation simple model using its general model parameters and establishing of operation general model objects as efficiency formula`s formal signs is presented in the article.

To conduct research, model of controlled system was created, structure of which is implemented as software product. Peculiarity of this model is possibility of carrying out experimental study, as result of which it is possible to detect changes in parameters of number of system operations under different control regimes.

As result of research, it was established that it is impossible to make comparative assessment between operations, which conducted in different control regimes, applying quantitative characteristics of input and output operational process parameters.

During creation of converting class system model structure, concept of operation reduction to its simple general model has been used. Model of program designer provides integration of cost parameters of input and output products by means of which, opportunity for efficiency determination of operations, functioning at different control modes is investigated. Analysis of operational process estimation results has shown that operation general model objects are formal signs of operations efficiency formula.

Different modes of optimum control to which have pointed extrema of several indicators have revealed absence problem systemically reasonable verification method of applied estimated indicators regarding their use as optimization criterion.

Practical importance of this research is that using presented program designer of controlled system and cybernetic approach allow apply results of research on all types of controlled systems. It promotes the optimization issue solution in finding of optimum mode of executive systems functioning and obtaining maximum economic effect of enterprise.
EXPERIMENTAL STUDY OF THE SUPERCONDUCTING MICROSTRIP ANTENNA AS A PROTECTIVE DEVICE OF THE RECEIVER FROM ELECTROMAGNETIC DAMAGE
Authors: Fyk Oleksandr , Kucher Dmutro , Gonchar Roman
Published: November 2017

The paper presents the results of experimental studies of a superconducting protective antenna, which consists of a high-temperature film deposited by a magnetron or a laser beam on a substrate. The work is carried out:

- analysis of the selection criteria for the substrate type (Al2O3, Y2O3, SrTiO3, MgO) and the method for depositing a high-temperature superconducting film (HTSF) on its surface – YBaCuO

- analysis of the methods of making contacts, which allow to reduce losses when passing a signal from the superconducting microstrip antenna to the waveguide path.

The aim of this article is determination of the parameters of a prototype sample of a microstrip antenna device made from HTSF: transient characteristics of high-temperature superconductors, HTSF impulsive characteristics, recovery time of the superconducting state after the action of a powerful pulse on the protective device, the amplitude-frequency characteristics of the protective device in the superconducting state. This will allow to evaluate the possibility of using a microstrip antenna device made from high-temperature superconductors to protect the receiving systems from electromagnetic damage. The absence of a unified theory of high-temperature superconductivity leads to the need to select an analytical form of the functions of the amplitude-frequency characteristics of superconducting protection, and for this mathematical models are used in the programs "APPROX", "MathCAD14.0". The reliability of the obtained results of mathematical modeling of the processes of protection and recovery of the superconducting state after electromagnetic shock are confirmed in the course of experimental studies (an error of 0.15%).
DEVELOPMENT OF A MODEL OF PROFESSIONAL READINESS FOR FUTURE PILOTS STUDYING AT HIGHER EDUCATION MILITARY INSTITUTES (HEMI)
Authors: Nevzorov Roman
Published: November 2017

The research seems to be important because Ukraine’s integration into international security and European educational systems provide for a high level of professional competence of Ukrainian Armed Forces officers (Ukraine AF), which is considered to be mandatory for assigned task execution, military personnel’s coordination in peacekeeping operations and joint military exercises with different countries, as well as for training, experience exchange, and competitiveness. The purpose of the research: The purpose of the article is to develop a model of best practice for future pilots in simulators. Methods of the research: The main method of the research is analysis of literature and documents regulating flight operations, in order to study issues and theoretical and methodological principles of the research and combat flight modeling in simulators to determine the nature and specifics of pilots’ activity at different stages of combat flights. Results of the research: The article describes a model of professional practice for future pilots, which includes components of their readiness for combat missions. The practical significance: The model is aimed at teachers’ adaptation to new conditions of training of future pilots at HEMIs and at improvement of simulator training.
TOXICOLOGICAL ASSESSMENT OF COMBINED FUNGICIDES PROPOSED FOR APPLICATION ON CEREAL SPIKED CROPS IN UKRAINE
Authors: Kondratiuk Mykola , Blagaia Anna
Published: November 2017

Toxicological assessment of combined fungicides proposed for application on cereal spiked crops in Ukraine was performed according approved State Sanitary Norms and Rules. Statistics, bibliographical methods were used in the study. The classes of hazard were established after evaluation of toxicometry parameters, which included assessment of acute oral toxicity, acute dermal toxicity, acute inhalation toxicity, irritation potential to eyes (mucous membranes) and skin, and sensitizing properties. Integral hazard class of the studied formulations was established. Formulations No.1, 2, 3, 5 and 7 can be pertained to integral hazard class 2 by acute inhalation toxicity as limiting criterion of hazard (formulation No.1 also has additional point of concern – its irritation of the skin and eyes). Formulation No.4, 6 and 8 were classified as integral hazard class 3 by the same limiting criterion of hazard, but the danger of formulation No.4 possibility to cause sensitization and irritation of the eyes was taken into account. Recommendations for the studied combined fungicides application in agricultural sector of Ukraine were given. Maximum daily time of contact with formulations for workers engaged in its application on cereal spiked crops was suggested. 4 hours per day were approved for formulations No.1,2,3,5 and 7, and 6 hours per day for No. 6 and 8, respectively
MICROBIOLOGICAL STUDIES OF ANTI-HISTAMINE SUPPOSITORIES "LORAVIT" FOR CHILDREN
Authors: Herasymova Iryna , Tikhonov Aleksander
Published: November 2017

Among the current problems of medicine and pharmacy, attracting the attention of researchers around the world, allergic diseases are on an important place; for example, bronchial asthma, allergic rhinitis, atopic dermatitis, and others. These pathologies affect their abundance not only among adults, but also among children [1]. According to statistics, almost every child had allergic reactions to drugs, food, clothing, hygiene products, etc. at least once [2]. In this regard, we have developed a new anti-allergic drug for children in the form of suppositories under the conditional name "Loravit". The purpose of this work was to conduct microbiological research of new anti-allergic drug "Loravit" for children in the rectal dosage form. During researches, the correlation of the growth properties of nutrients was analyzed and the microbiological purity of the drug "Loravit" was studied. A thioglyсol semi-liquid substratum, Saburo’s substratum, solid nutrient substrata: nutrient agar, Saburo’s substratum, Chistovich's substratum, nutrient agar based on blood agar, Endo’s substratum, and also test microorganisms - Staphylococcus aureus ATCC 6538, Esherichia coli ATCC 25922, Pseudomonas aeruginosa ATCC 9027, Bacillus subtilis ATCC 6633, Candida albicans ATCC 885/653 were used for carrying out these studies. In the study of microbiological purity, the method of direct seeding on liquid nutrient substrata and the method of deep sowing were applied. As a result of the conducted studies it was established that a new medicinal product for children in the form of suppositories for the treatment of allergic diseases meets the requirements of the State Pharmacopoeia of Ukraine and European Pharmacopeia for the indicator "Microbiological purity". The norms of microbiological purity of suppositories "Loravit" are also established. The test results were included in the draft quality control methods for the developed drug.
STUDY OF THE DISTRIBUTION OF AMLODIPINE IN ORGANS OF POISONED ANIMALS
Authors: Mamina Olena
Published: November 2017

Amlodipine besylate belongs to a group of blockers of calcium channels, derivatives of 1,4-dihydropyridine, is used to treatment of arterial hypertension and vasospastic forms of angina pectoris. According to the literature sources, amlodipine in case of overdose can provoke the development of breast cancer, cause ischemia of the optic nerve. Deadly poisoning with amlodipine may accompany drug overdoses or suicidal cases. The development of highly sensitive and selective methods for the study of amlodipine during forensic toxicological examination of biological material is an actual task. One of the important stages of forensic toxicological examination is the choice of organs of corpses for investigation of them for the presence of poisons, which requires the analysis of amlodipine in the organs of poisoned animals. The aim of the investigation is the study of the distribution of amlodipine in organs of poisoned animals, using developed highly sensitive and selective techniques for the analysis of amlodipine in biological objects. Materials and methods. To study the distribution of amlodipine in organs of poisoned animals, rats weighing 200-250 g were used. Amlodipine besylate solution was administered to rats using a probe in the stomach from the calculation of 70,0 mg / kg, after 3 hours rats were decapitated. For the study blood, urine, heart, liver, kidneys, lungs, stomach and intestine with contents and spleen were taken. Control experiments were delivered with the appropriate organs in parallel. Extraction of the substance was carried out with a mixture of methanol and acetonitrile (2: 3), purification was carried out by extraction of impurities with diethyl ether at pH 2,0-3,0 and TLC-method. Amlodipine was identified in biogenic extracts by the TLC-method in three systems of mobile solvents. The substance content was determined by spectrophotometry methods in the UV region of the spectrum. Results and discussion. It is established that the highest amount of amlodipine was found in the stomach and intestine with the content, which is typical for acute poisoning. Less amount of amlodipine is found in the liver, kidneys and urine - organs and liquids that provide active detoxification of the body. According to the results of the research, it was found that in case of lethal poisoning, amlodipine for forensic toxicological studies should be carried out in urine, stomach with contents, intestine with contents, liver, spleen and kidneys. Conclusions. The distribution of amlodipine in organs of poisoned animals with oral administration was studied. It is established that in case of lethal poisoning with amlodipine, for forensic-toxicological research it is necessary to be conducted in urine, stomach with contents, intestine with contents, spleen and kidneys. The developed methods can be proposed for introduction into the practice of the Bureau of Forensic Medical Examination, toxicological centers
RESEARCH OF ANTIMICROBIAL ACTIVITY OF ANTHELMINTHIC MIXTURE FOR NEMATODOSIS TREATMENT
Authors: Semchenko Kateryna , Romas Kateryna
Published: November 2017

Parasitic infections are one of the most acute problems of the modern society as this group of diseases is met in all countries of the world. According to the World Health Organization around 1.2 billion people are infected with diverse parasitic infections each year. Helminthiases of digestive system, primarily nematodosis, constitute a group of special risk, since a particularly sensitive audience for them are children of younger and middle age. Phytotherapy, which is based on the centuries-old experience of folk medicine, promises to be a solution to this problem, enabling to create effective complex medicines for nematodosis prevention and treatment. Thus, the herbal mixture was prepared on the basis of the offered composition of medicinal plant raw material. The research of antimicrobial activity of the studied herbal mixture was conducted in vitro by the method of diffusion into agar at the Biotechnology Department of the National Pharmaceutical University under the direction of Doctor of Pharmaceutical Sciences, prof. Strelets O.P. The obtained results of the carried out research of the antimicrobial properties of the herbal mixture samples allowed examining the level of antimicrobial activity. The further research of the investigated herbal mixture and the offered phytocomposition is promising for creation of new effective medicines with the complex action including anthelminthic (specific to nematodes), antiparasitic, anti-inflammatory, antibacterial, antiseptic, hepatoprotective, nephroprotective, laxative, antiallergic, antispasmodic, analgesic, sedative activities
CONTENT AND DYNAMICS DISCLOSURE OF PERSONALITY TRAITS OF PATIENTS WITH DIABETES MELLITUS TYPE 2 IN A CONTEXT OF DIABETIC PATHOPERSONOLOGY
Authors: Tkachenko Olha
Published: November 2017

Pathocharacteristic changes are denoted by a number of researches as complications of DM type 2. Certain personality traits such as alarming, anancastic and dependent personality traits are classically considered as one of the factors of getting DM type 2. The influence of pathopersonologic personality traits including acquired by DM on patients’ compliance to therapy stipulates high priority of their research. 543 patients with DM type two under medical treatment were examined. The first clinical group of 57 patients with DM type 2 with mild case. The second clinical group of 312 patients with moderately severe DM type 2. The third clinical group of 172 patients with nasty form of DM type 2. We have conducted research for five years (2012–2017 years). Methods of research: anamnestic, clinical-psychopathological, psychodiagnostical, statistical. There are established personality traits, which are predisposed by DM type 2. According to the induction risk level they are divided into such sections: section I – high risk of DM type 2 induction as one of the components of DM type 2 etiopathogenesis; section II – medium risk of DM type 2 induction; section III – low risk of DM type 2 induction. The research established the personality peculiarities of patients with DM type 2 and on its basis the modification of personological continuum of patients with DM type 2, as the disease progresses, was concluded. The established personality peculiarities of patients with DM type 2 can provide a basis for diabetic pathopersonoligy, that improves the quality of differential diagnosis of DM type 2 comorbid psychic disorders and approaches to DM type 2 therapy and psychoprophylaxis, the improvement of quality of patients’ with DM type two treatment, also in a context of compliance to DM type 2 therapy correction by the leveling of discompliant personality traits
The mitigation of liquidity risk in Islamic banking operations
Authors: Bello Nabil , Hasan Aznan , Saiti Buerhan
Published: November 2017

The purpose of this paper is to discuss the issues and challenges of liquidity risk management in Islamic banks. At the same time, the authors are going to identify the sources of liquidity risk in Islamic banks and the common instruments used to mitigate liquidity mismatches in both sides of their balance sheets. The study is a qualitative study that uses secondary sources of data to describe and analyze risk mitigation in the Islamic banking context. Data were collected from libraries by referring to books, journals from both online and offline sources. The research objectives were addressed by critically analysing various issues from both the Islamic principles and contemporary applications. The authors found that Islamic liquidity management is an important building block for stable and efficient banking. Even though there are several attempts, for example, i) organized tawarruq (commodity murabahah), ii) salam sukuk and iii) short-term ijarah sukuk, to find solutions to the incessant problems of liquidity faced by majority of Islamic banks, there are still several underlying problems such as i) in terms of deficiency in infrastructure especially in countries where Islamic finance is still at an early stage, ii) lack of hedging instruments and iii) Shariah restrictions on some instruments. Regulatory bodies should come up with more innovative practices of Islamic liquidity management to solve unresolved theoretical issues and also meeting market requirements for liquidity.