bluuebunny/crossref_metadata_2025 huggingface dataset:
PENDEKATAN ALGORITMA GENETIKA DALAM MENYELESAIKAN PERMASALAHAN FUZZY LINEAR PROGRAMMING
Authors: Dewi Lestari Siska , Subanar Subanar
Published: August 2020

Fuzzy linear programming is one of the linear programming developments which able to accommodate uncertainty in the real world. Genetic algorithm approach in solving linear programming problems with fuzzy constraints has been introduced by Lin (2008) by providing a case which consists of two decision variables and three constraint functions. Other linear programming problem arise with the presence of some coefficients which are fuzzy in linear programming problems, such as the coefficient of the objective function, the coefficient of constraint functions, and right-hand side coefficients constraint functions. In this study, the problem studied is to explain the genetic algorithm approach to solve linear programming problems where the objective function coefficients and right-hand sides are fuzzy constraint functions.PT Dakota Furniture study case provides a linear programming formulation with a given objective function coefficients and right-hand side coefficients are fuzzy constraint functions. This study describes the use of genetic algorithm approach to solve the problem of linear programming of PT Dakota to maximize the mean income. The genetic algorithm approach is done by simulate every fuzzy number and each fuzzy numbers by distributing them on certain partition points. Then genetic algorithm is used to evaluate the value for each partition point. As a result, the Final Value represents the coefficient of fuzzy number.  Fitness function is done by calculating the value of the objective function of linear programming problems. Empirical results indicated that the genetic algorithm approach can provide a very good solution by giving some limitations on each fuzzy coefficient.Genetic algorithm approach can be extended not only to resolve the case of PT Dakota Furniture, but can also be used to solve other linear programming case with some coefficients in the objective function and constraint functions are fuzzy.Keywords : Genetic Algorithm, Fuzzy Linear Programming, Linear Programming, Two-Phase Simplex Method
PENERAPAN SISTIM PENDUKUNG KEPUTUSAN DALAM SISTEM PENGUJIAN COMPUTERIZED ADAPTIVE TESTING
Authors: Rukli Rukli , Hartati Sri
Published: August 2020

This study aims to make design decision support system adaptive to examinee ability to go to college.Decision support systems are made using one parameter logistic model by taking into account the difficulty level of questions adapted to the ability of the examinee. Questions are selected so that the items follow the ability of examinee more accurate assessment of ability with a lesser number of items.CAT a web-based applications require lesser number of items in determining the ability of examinee. College can determine the appropriate characteristics of the ability of examinee acceptance criteria for each department with domain weighting, and then determine the minimum level of capability that will be received and an appropriate amount to be received. Key word: Decision Support System, Computerized Adaptive Testing
A HYBRID Approach for Determine the Location of Stand Establishment at Batik Hatta Semarang
Authors: Cholil Saifur Rohman , Pertiwi Leatitia Daphne Adhisti Putri
Published: August 2020

Semarang has various types of business. One of them is Batik Hatta Boutique, a small and medium business under the guidance of the Bank of Central Java that deals specifically in the world of batik art. This business develops and maintains its existence by participating in various exhibitions in several shopping centers as a media product promotion. To minimize losses, it needs accurate calculation in making decision of determining the location of establishment. It is reviewed by rental cost, location, layout, profit, and security. However, that calculation is still manual so it is inefficient and susceptible to error. Therefore, Decision Support System (DSS) is made to help in getting recommended location of best establishment at the Butik Batik Hatta. The method used in this research is the HYBRID MCDM AHP-TOPSIS Method. Validation process of this research has been done by using comparison of actual data and its result is 0.90 in the Sparman Correlation Coefficient. The conclusion is that the AHP-TOPSIS HYBRID MCDM method can be used in determining  the location of establishment stand at the Batik Hatta Boutique.
Klasifikasi Lagu Berdasarkan Genre pada Format WAV
Authors: Tamatjita Nurmiyati , Harjoko Agus
Published: August 2020

AbstrakDalam dunia yang berkembang pesat, media audio semakin komplek. Karena itulah diperlukan sebuah mekanisme penentuan jenis lagu (genre) yang tepat secara efektif dan efisien.  Pencarian secara manual sudah tidak efektif dan efisien lagi karena banyaknya data yang tersimpan.          Zero Crossing Rate (ZCR), Average Energy (E) dan Silent Ratio (SR) adalah 3 Feature Extraction yang digunakan untuk klasifikasi pencarian 12 genre.Tiga dimensi adalah bentuk visualisasi pengukuran tingkat kemiripan sebuah data berdasarkan hasil klasifikasi yang diinput oleh user.            Dalam penelitian ini pengujian klasifikasi menggunakan metode 3, 6, 9 dan 12 genre melalui jarak terdekat (Euclidean Distance). Hasil pengujian yaitu menunjukkan bahwa 3 genre yaitu Balada, Blues dan Classic menunjukkan = 96,67%, 6 genre yaitu Balada, Blues, Classic, Harmony, Hip Jop dan Jazz menunjukkan = 70% dan 9 genre yaitu Balada, Blues, Classic, Harmony, Hip Hop, Jazz, Keroncong, Latin dan Pop menunjukkan = 53,33% serta 12 genre = 33,33% Kata Kunci— Zero Crossing Rate (ZCR), Average Energy (E), Silent Ratio (SR), Euclidean Distance  Abstract            Music genre is getting complex from time to time. As the size of digital media grows along with amount of data, manual search of digital audio files according to its genre is considered impractical and inefficient; therefore a classification mechanism is needed to improve searching.            Zero Crossing Rate (ZCR), Average Energy (E) and Silent Ratio (SR) are a few of features that can be extracted from digital audio files to classify its genre. This research conducted to classify digital audio (songs) into 12 genres: Ballad, Blues, Classic, Harmony, Hip Hop, Jazz, Keroncong, Latin, Pop, Electronic, Reggae and Rock using above mentioned features, extracted from WAV audio files. Classification is performed several times using selected 3, 6, 9 and 12 genres respectively.            The result shows that classification of 3 music genres (Ballad, Blues, Classic) has the highest accuracy (96.67%), followed by 6 genres (Ballad, Blues, Classic, Harmony, Hip Hop, Jazz) with 70%, and 9 genres (Ballad, Blues, Classic, Harmony, Hip Hop, Jazz, Keroncong, Latin, Pop) with 53.33% accuracy. Classification of all 12 music genres yields the lowest accuracy of 33.33%.   Keywords— Zero Crossing Rate (ZCR), Average Energy (E), Silent Ratio (SR), Euclidean Distance
Analisis Tekstur untuk Klasifikasi Motif Kain (Studi Kasus Kain Tenun Nusa Tenggara Timur)
Authors: Setiohardjo Nicodemus Mardanus , Harjoko Agus
Published: August 2020

AbstrakIndonesia memiliki banyak kekayaan budaya dalam bentuk kain tradisional, salah satunya kain tenun dari Nusa Tenggara Timur (NTT). Kain tenun dari tiap etnik di NTT memiliki cirikhas motif masing-masing yang merupakan manifestasi kehidupan sehari-hari, kebudayaan dan kepercayaan masyarakat setempat. Di mata pemerhati kain tenun NTT, asal kain tenun dapat diketahui dari motifnya. Tidak semua orang dapat membedakan asal daerah dari motif kain tenun tertentu dikarenakan sulitnya mendefinisikan karakteristik motif kain tenun suatu daerah dan beragamnya motif kain tenun yang ada dan komposisi warna yang beragam pula.Analisis tekstur adalah teknik analisis citra berdasarkan anggapan bahwa citra dibentuk oleh variasi intensitas piksel, baik citra keabuan maupun warna. Motif kain tenun terbentuk dari variasi intensitas warna sehingga dapat dipandang sebagai tekstur berwarna dari kain tenun. Penelitian ini bertujuan untuk mengetahui diantara pendekatan analisis tekstur menggunakan Gray Level Co-occurrence Matrix (GLCM) yang dikombinasikan dengan momen warna dan pendekatan analisis tekstur menggunakan Color Co-occurrence Matrix (CCM), metode manakah yang memberikan hasil lebih baik untuk klasifikasi motif kain tenun NTT.Hasil penelitian menunjukkan bahwa untuk klasifikasi motif kain tenun NTT, pendekatan analisis tekstur menggunakan metode CCM memberikan hasil lebih baik dibandingkan pendekatan analisis tekstur menggunakan GLCM yang dikombinasikan dengan momen warna. Kata kunci—klasifikasi citra, GLCM, CCM, momen warna, motif kain tenun NTT AbstractIndonesia have many culture in the form of traditional fabrics, one of them is woven fabric from Nusa Tenggara Timur (NTT). Each NTT ethnic has motif characteristic which ismanifestation of daily life, culture and the faith of local people. For a NTT woven fabric observer, the origin of a woven fabric can be known from the motif. But its difficult to recognising the origin of a woven fabrics because it is hard to define the characteristics of woven fabric motif from a region and wide variety of existing woven fabric motifs and also color composition.Texture analysis is image analysis technique based on assumption that an image formed by the variation of pixels intensity, both gray and color image. Woven fabric motif formed by the variation of color intensity that can be seen as color texture of the woven fabric. This study aims to determine between texture analysis using GLCM combined with color moment and texture analysis using CCM, which method gives better results for the NTT woven fabric motif classification.The results showed that for the NTT woven fabric motif classification, texture analysis using CCM gives better results than the texture analysis using GLCM combined with color moment. Keywords— image classification, GLCM, CCM, color moment, NTT woven fabric motif
Battle of Poznan of 19 August 1704 between the Saxon and Swedish Armies
Authors: Koscielniak Karol
Published: August 2020

The battle of Pozna? between the Swedish army commanded by Johann August Meijerfelt and the Saxon army commanded by general Johann Matthias von der Schulenburg began at the dawn of 19 August 1704. The Saxon general had a major advantage in terms of army strength. He was therefore able to push back the Swedish army from the city, but did not capture the tower. The lack of broader researcher interest and the relatively high number of remaining source materials contributed to the tackling the subject. It is worth shedding light on all events that faded into the historical abyss and are forgotten, or worse, are enveloped by false myths. The Republic of Poland, which became an arena for direct military action in 1702-1709 during the Great Northern War, suffered much pain and destruction despite not officially participating in the war. It is perhaps this fact that makes the conflict and its effects difficult to find among valuable Polish historiography works that would objectively show its course and above all the art of war of the early XVIII century. This paper represents only a small droplet of what remains to be done in terms of describing each aspect of the Great Northern War.
Health benefits and economic advantages associated with increased utilization of a smoking cessation program
Authors: Datta Santanu K , Dennis Paul A , Davis James M
Published: August 2020

Rationale, aim & objective:The goal of this study was to examine the health and economic impacts related to increased utilization of the Duke Smoking Cessation Program resulting from the addition of two relatively new referral methods – Best Practice Advisory and Population Outreach.Materials & methods:In a companion paper ‘Comparison of Referral Methods into a Smoking Cessation Program’, we report results from a retrospective, observational, comparative effectiveness study comparing the impact of three referral methods – Traditional Referral, Best Practice Advisory and Population Outreach on utilization of the Duke Smoking Cessation Program. In this paper we take the next step in this comparative assessment by developing a Markov model to estimate the improvement in health and economic outcomes when two referral methods – Best Practice Advisory and Population Outreach – are added to Traditional Referral. Data used in this analysis were collected from Duke Primary Care and Disadvantaged Care clinics over a 1-year period (1 October 2017–30 September 2018).Results:The addition of two new referral methods – Best Practice Advisory and Population Outreach – to Traditional Referral increased the utilization of the Duke Smoking Cessation Program in Primary Care clinics from 129 to 329 smokers and in Disadvantaged Care clinics from 206 to 401 smokers. The addition of these referral methods was estimated to result in 967 life-years gained, 408 discounted quality-adjusted life-years saved and total discounted lifetime direct healthcare cost savings of US$46,376,285.Conclusion:Health systems may achieve increased patient health and decreased healthcare costs by adding Best Practice Advisory and Population Outreach strategies to refer patients to smoking cessation services.
МЕТОДИКА ОЦЕНКИ НАДЕЖНОСТИ СЕТЕЙ СВЯЗИ
Authors: Довгий С. , Сторожук М. , Сторожук Н.
Published: August 2020

В статье рассмотрены способы определения надежности сетей связи в свете "Правил подготовки и использования ресурсов единой сети электросвязи Российской Федерации для обеспечения функционирования значимых объектов критической информационной инфраструктуры". Предложена методика анализа надежности для оценки целесообразности использования ресурсов телекоммуникационной сети конкретного оператора для обеспечения функционирования значимых объектов критической информационной инфраструктуры.
Astrological Parlance of Macro and Micro Nutrients
Authors: Pawar Rajendra Singh , Dimri Mayank , Kush Luv
Published: August 2020

The dietary minerals are astro-elements . They maintain normal biochemical physiology and anatomical strength. Their deficiencies under unfavorable planetary configurations cause health-maladies.
Method Development and Validation of A Novel Anti-Depressant Bupropion by RP-HPLC
Authors: Kumar Anil , Agarwal Dilip , Bansal Mukesh
Published: August 2020

A speedy, simple and precise RP-HPLC process was developed for the estimation of novel antidepressant drug bupropion with Waters X – Bridge C-18 5µm, 4.6 X 150 mm columnusing mobile phase Acetonitrile: Ammonium bicarbonate (5mM) pH-9 adjusted with 1% Ammonium hydroxide (50:50, %v/v).The flow rate was 1 ml/min and quantification was done by PDA detector at wavelength254nm.The Bupropion eluted from the column in 5.194 min. The validation was carried out in the light of ICH guidelines with respect to parameters linearity, specificity, accuracy, limit of detection (LOD) and limit of quantification (LOQ). The proposed method showed linearity in the concentration range of 50 to 250 ppm for Bupropion. The linear regression equation of Bupropion was found to be y = 6E+06x + 91344 and correlation coefficient value was found to be 0.997 indicating a high degree of linearity for the drug. The limit of detection (LOD) of bupropion was 0.5 ppm and limit of quantification (LOQ) was 2.0 ppm. The low values of %recovery and %C.V. showed that the method is precise within the acceptance limit of 5% (according to ICH guidelines).
Review on Liposome as Novel Approach for Cancer Therapy
Authors: Singh Lodhi Devendra , Ganju Kuldeep , Rajpoot Ramkumar
Published: August 2020

The main objective is to study the importance of liposome in drug targeting in cancer cells andgo through various research work going through on liposome. The importance of liposomes to study the flexibility to couple with the specific ligands toachieve active targeting. Cancer can be treated by surgery, radiation, chemotherapy, gene therapy, immunotherapy, hormone therapy. Cancer is the uncontrolled growth of abnormal cell anywhere in a body. The abnormal cells aretermed cancer cells, malignant cells, or tumor cells. There were 14.1 million new cancer cases, 8.2 million cancer deaths and 32.6 million people living with cancer (within 5 years of diagnosis) in 2018 worldwide. 57% (8 million) of new cancer cases, 65% (5.3 million) of the cancer deaths and 48% (15.6 million) of the 5-year prevalent cancer cases occurred in the less developed regions.
Duchene Muscular Dystrophy: Pathogenesis, Pathophysiology, Diagnosis Management to Therapy.
Authors: Sharma Bharti , Devi Savita , Singh Kamaldeep
Published: August 2020

Duchene muscular dystrophy (DMD) is a neuromuscular inherited disease which deal with X-linked occurs due to mutations in the dystrophin gene. The characterisation achieved by progressive muscle weakness in all our the body specially in legs and arms and wasting due to the absence of dystrophin protein which further causes degeneration of different types of muscules such as skeletal and cardiac. Gene mutation is one of the major causes for Duchenne muscular dystrophy located in cytoskeletal protein dystrophin. The diagnosis can be start up with careful review of the physical condition, history and examination of body organs and developmental delay, proximal weakness in muscules, and elevated biochemical compound serum creatine kinase, plus other confirmatory test like muscle biopsy or genetic testing. To improve the life expectancy of patient the early use of exercises, diet & nutrition management and other supportive strategies has been implemented. Moreover, uncontrolled condition can be treated with gene therapy with the use of plasmids or viruses, mutations and short DNA fragments can be corrected, oligonucleotides are first line treatment for exon skipping of mutations. Myoblasts or stem cells replacement therapy can be apply to reproduction of muscules.
Design, Development and Evaluation of Gliclazide Tablets for Non-Insulin Dependent Diabetes Mellitus
Authors: Dave Vikas , Jain Amit , Agarawal Dilip
Published: August 2020

The goal of the present work was to formulate the oral tablets of gliclazide for non-insulin dependent diabetes and provide a dosage form for prolonged period of time, in order to improve efficacy, reduce the frequency of total dose and better patient compliance. The powders were evaluated for angle of repose, bulk density, compressibility index and hausner’s ratio. All the tests revealed that powders showed excellent flow properties. The resulting tablets were evaluated for thickness, diameter, and uniformity of weight test, hardness, friability and drug content. In-vitro release of drug was performed using 7.4 pH phosphate buffers and dissolution was done. All the tablet formulations showed acceptable pharmacological properties and complied with pharmacopoeias standards.
Burn Wound Healing Activity of Ethanolic Extract of Acalypha indica in Oinment Formulated against Rabbits (Ocyctagus caniculus)
Authors: Fitri Khairani , Khairani Tetty Noverita , Sinaga Fajar Apollo , Talunohi Amenia Gracia
Published: August 2020

Objectives: The purpose of this study was to determine burn wound healing activity of Acalypha indica L. in oinment formulated.

Design: This study uses an experimental laboratory design. This study used rabbits as test animals induced by burns with hot iron plates on the back. Extract ointment applied to the wound then observed the development of healing.

Interventions: The extract was formulated in ointments with concentrations of 3, 5 and 7%. positive control used was ointment containing sesame oil and negative control used is an ointment base.

Main outcome measure: The results showed a concentration of 3% had a slow and low effect, at a concentration of 5% it had a moderate healing phase, and a concentration of 7% had a good healing phase.

Conclusion: The ointments containing Acalypha indica leaf extracts have good activity in healing burns in rabbits.
A Scientific Update on Juglans Regia Linn.
Authors: Verma Gunjan , Sharma Vandana
Published: August 2020

Medicinal herbs having a great role in human health care and welfare services. These herbs widely used in Ayurveda, Homeopathic and Allopathic system having various therapeutic properties. Walnut (Juglans regia L.) are the plants belonging to the family Juglandaceae commonly known as Akhrot. It is widely distributed in China, United State, Jammu & Kashmir, Himachal Pradesh, Arunachal Pradesh, Uttarakhand. It has different varieties such as Black walnut, English/Persian walnut, butternut/white walnut. J.regia L. have many marketed formulations such as Topical formulations like Walnut oil, Face wash, Exfoliating scrub, Soap, Shampoo, Hair color and Oral formulations like capsules, tinctures, dilutions, shell powder. Chemical study reveals that J.regia L. contains Juglone, Alkaloids, Flavonoids, Saponins, Polyphenols, Polyunsaturated fatty acids, Oleic acids, Linoleic acids, Proteins, Napthaquinones, Ascorbic acid, Sitosterol, Tannins. Walnut contains different nutritional components like Carbohydrates, Proteins, Dietary fibres, Iron, Phosphorus, vitamin E & C. This plant possess beneficial effects include Antimicrobial, Antioxidant, Anticancer, Antidiabetic, Anthelmintic, Antiinflammatory, Antidepressant, Hepatoprotective, Antiulcer, Antiageing and Hypocholestermic activity and other therapeutic activities. It is believed to be used in Dental plaque, Gingivitis, Oral hygiene, Eczema, Hemorrhoids, Burns, Blood Purifier, Dyeing or Colorant, Antiseptic and Astringent. In the present study, Pharmacognostic and Pharmacological properties of J.regia L. have been discussed. This review highlights the various Ethanobotanical and traditional uses as well as Pharmacognostic and Pharmacological report on J.regia L.
Histopathological Changes in the Spleen of Swiss albino Mice after the Combined Exposure of Radiation and Cadmium
Authors: Daverey Jaishree
Published: August 2020

With the technological advancement and diversification of industries, combined with specialization in all fields, the volume and complexity of metals is also increasing day by day. Interaction of metals with other agents is an important aspect as both can interact in a “synergistic” or “additive synergistic” manner, further aggravating the situation. In the present study, combined effect of radiation and cadmium on spleen of mice has been investigated. For the experiment, adult, healthy male Swiss albino mice were exposed to different doses of radiation and also fed with the aqueous solution of CdCl2 which was prepared by dissolving 20 mg of cadmium chloride in 1000 ml of glass distilled water, thus giving a concentration of 20 ppm and then administered orally ad libitum in drinking water continuously, till the end of the experiment. Animals were autopsied by cervical dislocation at each post- interval of 1, 2, 4, 7, 10, 14 and 28 days. Spleen was taken out, weighed, fixed in Bouin’s fluid, dehydrated and embedded in paraffin wax. Transverse sections were cut at 5µ from middle part of the tissue and stained with Harri’s haematoxylin-eosin stain for histopathological studies. Pathological changes after combined exposure in the present investigation depends upon the total dose of radiation provided i.e. higher the dose, higher the damage. Most striking histopathological change in the spleen was loss of lymphoid structure, inflammation, fibrous tissue proliferation, pyknosis, necrosis, karyolysis, karyorrhexis.
A Review on 2019-nCoV (SARS-CoV-2) in India
Authors: Mahawar Pawan Kumar , Sharma Abhay
Published: August 2020

Background: The outbreak of the novel coronavirus, COVID-19, has been declared a pandemic by the WHO on March 11th of 2020. Novel Coronavirus infection mediated pandemic started in China in December 2019 and is still killing 1000s of people throughout the world. The second most populous country, India too is fighting against this infectious disease. The country is taking effective measures to curb the pandemic by exerting extensive campaigning on sanitation and strict social distancing measures to quell the explosion of the infection rate.

 Treatment: No drugs are currently approved for Coronavirus Disease-2019 (COVID-19), although some have been tried. In view of recent studies and discussion on tested drugs on COVID-19 patients of India, I aimed to review existing literature and relevant websites regarding these drugs used in India including allopathic, plasma therapy,Ayurvedic and homeopathic medication.
Model of Anti-Covid-19 Pharmacon
Authors: Dimri Mayank , Rajwar Virbal Singh , Kush Luv
Published: August 2020

COVID-19 pandemic opens multiple opportunities for innovations in the drug –design. Combinational therapeutics and renewal of orphan drugs as antivirals. The drugs of pharmacological diversity may be tomorrow of viral replication blockers. A model of polyactive pharmacon is suggested for hybridizing structural moieties of virucidal relevance.
Protective Effect of N-Acetyl Cysteine on Moringa Oleifera Aqueous Leaf Extract-Induced Hepatic Toxicity in Wistar Albino Rats
Authors: Agnes Namaganda , Josephine Kasolo N , Godfrey Bbosa S. , Robert Lukande , Ivan Kimuli , Godfrey Katamba , Haruna Muwonge , Isaac Okullo , Joshua Nfambi
Published: August 2020

Background: Moringa oleifera (M. oleifera) is a commonly used medicinal and nutritive plant. The aqueous leaf extract from this plant contains a high concentration of alkaloids and they are toxic to body organs especially the liver leading to hepatotoxicity after long term exposure. However, if N-Acetyl cysteine (NAC) is administered together with M. oleifera extract, it may have a hepatotoxic protective effect.

Objective: To establish the protective effect of N-Acetyl cysteine against M. oleifera aqueous leaf extract-induced hepatotoxicity in the Wistar albino rats.

Methods: An experimental laboratory-based study conducted at department of Physiology Makerere University, College of Health Sciences. Three treatment groups of six Wistar albino rats each, were dosed intragastrically once a day for 28 days. Group I; negative control, received 8.05g/kg bwt of M. oleifera extract plus 1ml of normal saline (NS), Group II; test group, received 8.05g/kg bwt of M. oleifera extract plus 50mg/kg of NAC. Group III; positive control, received 750mg/kg bwt of Paracetamol plus 50mg/kg of NAC. On the 14th and 29th day, three animals selected randomly from each group were sacrificed; blood samples were collected, the liver was harvested for histopathological analysis.  Serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), bilirubin and total protein levels were determined.

Results: There was an increase in serum ALT, AST and ALP levels in the M. oleifera extract plus NS group which was a sign of hepatotoxicity. The M. oleifera extract plus NAC group showed normal serum ALT, AST and ALP levels with no significant changes in the bilirubin (P-value = 0.9089) and total protein levels (P-value = 0.8858).

Conclusion: The results have provided evidence that NAC administration with M. oleifera extract effectively prevents the occurrence of M. oleifera leaves xtract- induced hepatotoxicity.
A Review on Medicinal Plants of North Eastern Region with Potential Antifertility Activity
Authors: Goswami Priyanka , Laskar Moksood Ahmed , Basak Mrinmoy
Published: August 2020

The increase in population is becoming a comprehensive problem, causing much pressure on economic, social and natural assets. Oral contraceptive agents have improved the rate of infertility but their unusual side effects limit the use. Current antifertility therapy lacks satisfactory success due to this adverse effect; hence, patients are seeking complementary and alternative medicine for anti-fertility action. Ayurveda and other Indian literature mention the use of plants in various human ailments. India has about more than 45000 plant species and among them several thousand are claimed to possess medicinal properties. Researchers conducted in the last few decades on the plants mentioned in ancient literature or used traditionally for anti-fertility action. This review reveals that some plants and their part used having anti-fertility action, which are helpful for researcher to develop new herbal anti-fertility formulations. In the recent years, interest in drugs of plant origin has been progressively increased. The aim of this review is to highlight the work on anti-fertility of plant origin. For women who can't use modern forms of contraception due to adverse effect or other reasons, therefore herbs can offer alternatives and reducing fertility would be better than other contraceptives. This article may help investigators to identify medicinal plants responsible for anti-fertility activity.
A Technical Review: Solid- Lipid Nanoparticle (SLN), Their Characteristics and Their Preparation
Authors: Bhattacharjee Sunirmal , Debnath Rabindra , Kumar Sinha Ashutosh , Saha Arpan , Saha Surajit , Debnath Sujata
Published: August 2020

Solid lipid nanoparticles are at the forefront of the rapidly developing field of nanotechnology with several potential applications in drug delivery, clinical medicine and research as well as in other varied sciences. Due to their unique size-dependent properties, lipid nanoparticles offer the possibility to develop new therapeutics. The ability to incorporate drugs into nanocarriers offers a new prototype in drug delivery that could be used for secondary and tertiary levels of drug targeting. Hence, solid lipid nanoparticles hold great promise for reaching the goal of controlled and site specific drug delivery and hence have attracted wide attention of researchers. This review presents a broad treatment of solid lipid nanoparticles discussing their advantages, limitations and their possible remedies. The different types of nanocarriers which were based on solid lipid like solid lipid nanoparticles, nanostructured lipid carriers, lipid drug conjugates are discussed with their structural differences. Different production methods which are suitable for large scale production and applications of solid lipid nanoparticles are described. Appropriate analytical techniques for characterization of solid lipid nanoparticles like photon correlation spectroscopy, scanning electron microscopy, differential scanning calorimetry are highlighted. Aspects of solid lipid nanoparticles route of administration and their biodistribution are also incorporated. If appropriately investigated,solid lipid nanoparticles may open new vistas in therapy of complex diseases.
Emulgel: A Topical Preparation
Authors: Parihar Nikhita , Saini Mahendra , Soni Shankar Lal , Sharma Vandana
Published: August 2020

Emulgel is an emerging topical drug formulation which is becoming increasingly popular due to its advantages over the conventional topical preparations. The emulgel is a combination of an emulsion and a gel and thus has a dual release control system. Its biggest and most favorable advantage has been the ability to incorporate hydrophobic drugs, thus making it emerge as a more popular choice these days. The emulgel is also greaseless, transparent; it can be easily spread and removed, has a long shelf- life, is thixotropic and is also pleasant looking. The emulgel is turning out be a preferred choice for cosmetic and dermatological preparations and its use and application will accelerate in the coming future.
A Review on Self Micro Emulsifying Drug Delivery System: An Approach to Enhance the Oral Bioavailability of Poorly Water Soluble Drug
Authors: Patil Mamta , Palde Shobha , Deshmukh Amol
Published: August 2020

Self-micro emulsifying drug delivery framework is the one of the methodology for improving the solvency of the hydrophobic medication. The medications which are insoluble in water can be formulated in this technique by solubilizing it in the lipid vehicle to absorb through the membrane. The lipid and surfactants are utilized to build the solvency of the drug and improve absorption. This improves the dissolution rate of the drug by expanding its solubility. A large number of the obstacles and arrangements are depicted in this article. This system picked up consideration as it likewise improves the bioavailability of the drug. This article has total survey about SMEDDS for present work and for future viewpoint too.
Modelos neuropsicologicos y neuroimagen de las alteraciones cerebrales ocasionadas por la cocaína
Authors: Borda Riveros Nelly Julia
Published: August 2020

La presente revisión de literatura hace referencia a los modelos que la neuropsicología manifiesta en relación a la drogodependencia, con el propósito de explicar el origen y desarrollo de los trastornos adictivos, respaldados por medio de la neuroimagen. El modelo clásico de la adicción, propuesto por Wikel (1965), el cual fue reformulado por nuevos modelos, entre los más destacados, el modelo basado en la transición entre impulsividad y compulsión de Everitt y Robbins (2005), el modelo de alostasis y estrés de Koob y Le Moal (2001, 2008), y el modelo de la sensibilización al incentivo de Robinson y Berridge (2001, 2003, 2008). De manera alternativa surgió el modelo (I-RISA) de Goldstein y Volkow (2002). Al final se formuló el modelo somático de las drogodependencias propuesto por Verdejo-García y Bechara (2009) y Pérez-García y Bechara (2006). Por último se aborda la recuperación o rehabilitación de la adicción desde una perspectiva neurológica y neuropsicológica.
Caracterización de la Paráfrasis en Estudiantes Universitarios
Authors: Cepeda Islas María Luisa , Hickman Rodríguez Hortensia , Becerra Ramírez J. Jesús , Zavaleta Cepeda Raúl , Ruíz Méndez David
Published: August 2020

La paráfrasis se puede concebir como la habilidad que tiene el lector o un escucha de reformular las ideas principales de un texto o un hablante sin distorsionarlas. Para elaborarla es indispensable contar con un dominio del idioma. En el ámbito universitario esta habilidad es importante porque es una manera de fomentar la comprensión lectora. Algunos autores han planteado diferentes tipologías de paráfrasis por ejemplo Barrón-Cedeño, Vila y Rosso (2010). Aun cuando esta habilidad es trascendente en la formación universitaria, no existe una caracterización del tipo de paráfrasis que usan los universitarios. El presente trabajo tuvo como objetivo caracterizar el tipo de paráfrasis utilizado por los estudiantes universitarios. Bajo un estudio de tipo descriptivo transversal, participaron 133 estudiantes de la carrera de psicología en la Facultad de Estudios Superiores Iztacala. Para la evaluación de la paráfrasis se implementó un inventario con 20 ítems diseñado bajo la propuesta por Barrón-Cedeño et al. (2010). Los resultados, muestran que los estudiantes emplean con mayor frecuencia la tipología de cambio de orden, en cuanto a la complejidad, se observa una preferencia por las paráfrasis de complejidad media. Si bien se encontraron diferencias entre los semestres, estas no son estadísticamente significativas. Se sugiere el diseño de programas para fortalecer dicha habilidad
Evaluación de un programa piloto para desarrollar la conducta prosocial en niños de edad escolar.
Authors: Herrera Lozano Jennifer Stefania , Musi Lechuga Bertha
Published: August 2020

El presente estudio fue un pilotaje para la adaptación del programa JUEGO, con el propósito de incrementar la conducta prosocial de los niños participantes por medio de juegos cooperativos. Se desarrolló con 37 niños con edades comprendidas entre los ocho y 10 años, mediante un diseño cuasiexperimental pre-post de un solo grupo, muestreo por conveniencia con variables cuantitativas y cualitativas. Entre los resultados se destaca que hubo un incremento reportado por los niños en la conducta prosocial y una disminución estadísticamente significativa en la conducta agresiva p= 0.024 y en la pelea p= 0.018. Se concluye que es posible incrementar la conducta prosocial y disminuir las conductas agresivas que inciden en el acoso escolar con la implementación del programa basado en juegos cooperativos.
Plutarco: antigos hábitos dos lacedemônios
Authors: Silva Maria Aparecida de Oliveira
Published: August 2020

Esta é a tradução de Τὰ παλαιά τῶν Λακεδαιμονίων ἑπιτηδεύματα ou Antigos hábitos dos lacedemônios, de Plutarco. Trata-se se um tratado composto por 42 anedotas, ditos e episódios que retratam o período arcaico espartano, quando a cidade de Esparta era regida pelas leis de Licurgo.
O SENSORIAMENTO REMOTO APLICADO NA ANÁLISE DAS TRANSFORMAÇÕES DO USO E COBERTURA DA TERRA NA MICROBACIA DO RIO MAGU, MARANHÃO, BRASIL
Authors: Costa Francisco Wendell Dias , Mendes Pereira Paulo Roberto
Published: August 2020

O objetivo deste trabalho é analisar as transformações do uso e cobertura da terra na Microbacia do rio Magu, comparando os anos de 2000 e 2017. Para essa análise foram utilizadas imagens de satélites do Landsat 5 e 8 Path/Row 219/062, datadas de 28 de agosto de 2000 e 11 de agosto de 2017. O Processamento Digital de Imagem (PDI) foi realizado no SPRING versão 5.5.3, já o mapeamento das classes de uso e cobertura da terra para as datas supracitadas foi realizado no software QGIS 2.18. Sendo assim, foi possível identificar e classificar 6 (seis) classes: água, áreas antropizadas, mata de galeria, vegetação aquática, vegetação densa e vegetação rasteira. Os resultados evidenciaram que a área de estudo sofreu transformações no uso e cobertura da terra nos anos analisados, sobretudo com redução de áreas de vegetação densa e aumento das áreas antropizadas, decorrente do crescimento urbano desordenado e do avanço das práticas agrícolas temporárias (sojicultura) afetando a paisagem no local.
CONDOMÍNIOS INDUSTRIAIS NA REGIÃO METROPOLITANA DA GRANDE VITÓRIA, ES: O CASO DO CONDOMÍNIO VIANA LOG.
Authors: Bassani Izabela Dolores Cebin , Monteiro Rafael Santos da Luz , Leão Rose Mary Nunes , Campos Júnior Carlos Teixeira de , Assis Leandro Camatta
Published: August 2020

Os condomínios industriais são produtos imobiliários contemporâneos que abrigam em seu arranjo interno a indústria e outras formas de reprodução do capital. São produtos de uma nova fase da produção da cidade que nega a forma antiga – centro-periferia, e ressalta a produção de novas centralidades, contribuindo para o espraiamento do tecido urbano. A reestruturação imobiliária apresenta-se como conceito-chave para a análise da produção do espaço urbano atual, uma vez que permite uma abrangente visão sobre as questões socioespaciais. O conceito de reestruturação imobiliária foi escolhido por duas razões: a primeira delas é o destaque para a produção de novas formas urbanas e sua relação com a reestruturação produtiva da indústria da construção, e a segunda é o reconhecimento de mudanças significativas no processo de urbanização desencadeada por essa relação. O objetivo deste trabalho é entender o processo interno de reestruturação do capital na construção a partir da produção de condomínios industriais, apresentando as características do condomínio industrial Viana Log. A revisão de literatura e a análise empírica dos empreendimentos nos possibilitaram perceber que a RMGV se tornou o principal lócus de produção dos CI’s, que se tornaram um produto imobiliário capaz de gerar renda, lucro e ativo.
IMPLICAÇÕES DAS ALTERAÇÕES NO USO E OCUPAÇÃO DO SOLO NAS PERDAS DE SOLO DA BACIA DO RIO DE ONDAS, ESTADO DA BAHIA
Authors: Bagnara Fistarol Pedro Henrique , Gomes dos Santos José Yure
Published: August 2020

O início da ocupação na região Oeste da Bahia para fins agrícolas ocorreu no final da década de 1970, o que acarretou uma intensa degradação da vegetação nativa de Cerrado ali existente. Dentre as bacias que passaram por esse processo intenso de alteração no seu uso e ocupação do solo destaca-se a Bacia do Rio de Ondas, que é uma das principais sub-bacias do Rio Grande, que por sua vez é o último grande tributário da margem esquerda do Rio São Francisco. Diante dessa problemática, o presente trabalho tem como objetivo analisar as implicações das alterações no uso e ocupação do solo da Bacia do Rio de Ondas na sua produção de sedimentos. Para tanto foi utilizada a USLE em ambiente SIG e analisadas as perdas de solo para os cenários de 1975 e 2015. Em que foi constatado que a Bacia do Rio de Ondas passou por uma intensa alteração no seu uso e ocupação do solo nos últimos 40 anos, com a supressão de cerca de 47% de área de vegetação nativa, o que influenciou de maneira significativa no aumento da produção de sedimentos da bacia, tendo como fatores de maior influência o fator topográfico (LS) e o de uso e ocupação do solo (C). As perdas de solo na Bacia do Rio de Ondas foram consideradas moderadas, para as condições atuais de uso e ocupação do solo, mas podem ser intensificadas com o aumento da substituição da vegetação nativa por áreas agrícolas.
ESPAÇO URBANO E RELAÇÕES DE GÊNERO: Um estudo de caso sobre a mobilidade do trabalho e a morfologia socioespacial das cidades
Authors: Garcia Maria Franco , Lebrão Jemeffer Souza , Passos Sinval Almeida
Published: August 2020

O objetivo deste texto é apresentar uma reflexão sobre o processo de expansão da cafeicultura no planalto de Conquista no estado da Bahia, mostrando como a mobilidade da força de trabalho de homens e mulheres participaram da configuração da forma urbana da cidade de Vitoria da Conquista, originando grande parte do que hoje conhecemos como sua periferia. Os resultados alcançados nos permitem afirmar que a produção da periferia urbana é parte do processo de mobilidade do trabalho ao tempo que, a reprodução desse espaço está condicionada pelas relações sociais de gênero.
Combatendo as “plantas exóticas” da Nação:
Authors: Cavalcanti Junior Manoel Nunes
Published: August 2020

Em 1836 a Regência passava por um momento de crise política com os desdobramentos das medidas liberais e descentralizadoras implementadas desde o 7 de abril de 1831. Começava a surgir um movimento de cisão entre os liberais moderados que até então controlavam o poder na corte e de contestação àquelas medidas. Era o início do Regresso. Na província de Pernambuco os regressistas foram representados pela oligarquia dos Cavalcanti em aliança com os restauradores locais do grupo do futuro regente Araújo Lima. Utilizando-se dos meios disponíveis de luta política pela imprensa e do controle da Assembleia Provincial, estes novos regressistas pernambucanos conseguiram aprovar uma lei provincial que anulou muitas das medidas descentralizadoras e deu nova roupagem centralizadora à estrutura judiciária e policial da província, antecipando as mudanças a nível nacional que só seriam tomadas com a Lei de Interpretação do Ato Adicional de 1840. Este artigo se propõe a analisar o processo como se deu esta vitória dos regressistas em Pernambuco e suas implicações para a luta política local.
Recomendações da Diplomática para o uso de documentos arquivísticos digitais nas plataformas do tipo blockchain
Authors: Fernandes do Nascimento Cynthia Giovania , Dorneles Sânderson Lopes
Published: August 2020

Os avanços tecnológicos ocorridos no século XXI, influenciaram na forma como as pessoas vem registrando as suas informações, ocorre que cada vez mais sistemas do tipo Blockchain são desenvolvidos para oferecer praticidade, rapidez, segurança e transparência no momento do registro suas informações. Diante desse contexto, diversos documentos estão sendo produzidos sem as devidas orientações estabelecidas pela Diplomática para que possam ter a sua autenticidade, fidedignidades e preservação garantidas. Portanto, o objetivo do trabalho o de é investigar, através dos fundamentos da Diplomática, como garantir a autenticidade, fidedignidade e preservação de documentos arquivísticos digitais utilizados nas plataformas do tipo Blockchain. Para isso, utilizou-se a revisão sistemática da literatura somada a uma análise de casos de utilização de plataformas do tipo Blockchain. A partir dos estudos, foi possível sugerir recomendações para tratar os documentos arquivísticos digitais inseridos no sistema estudado. Tais orientações referem-se ao modelo de implementação estrutura arquivística, as normas para a criação de sistema de gerenciamento arquivístico de documentos de valor corrente e intermediário e de preservação de documentos de valor intermediário e permanente e o modelo metadados para o gerenciamento arquivístico de documento e o modelo de Padrão de metadados para gerenciamento arquivístico.
Editorial
Authors: Carvalho Ediane Toscano Galdino
Published: August 2020

Editorial do v.7, n.2, jan./jun.2020 da Revista Archeion Online
A ascensão chinesa no sistema capitalista global contemporâneo: uma análise sob a ótica da Escola de Amsterdã
Authors: Fortes Ana Rachel Simões
Published: August 2020

A nova conjuntura do sistema capitalista global é marcada pelos questionamentos e debates sobre as práticas neoliberais. Nesse cenário, a emergência da China como um importante player na economia-mundo capitalista, surge como um dos fenômenos mais significativos no contexto internacional, resultando em diversas análises sobre o seu suposto papel contra- hegemônico. Dessa maneira, este trabalho se propõe a apresentar as contribuições teóricas da Escola de Amsterdã sobre os impactos políticos e econômicos da China na nova configuração da ordem mundial no século XXI. Através do entrelaçamento e discussão dos estudos da Escola de Amsterdã, espera-se contribuir com o debate acerca das reconfigurações dos núcleos de poder e os rumos das relações internacionais neste século.
Securitizar para controlar
Authors: Oliveira Caio Guimarães
Published: August 2020

A Wikileaks realizou diversos vazamentos de documentos confidenciais de Estados e empresas desde sua criação, em 2006, por Julian Assange. Esses vazamentos geraram repercussões que possuem potencial desestabilizador no Sistema Internacional podendo levar a mudanças. Como aporte teórico utilizaremos a teoria da Securitização para analisar se houve alguma campanha no sentido de comprometer a atuação da Wikileaks perpetrada pelo ator mais interessado na manutenção do status quo internacional, os Estados Unidos. Essa investigação se baseia na análise do discurso de pessoas ligadas ao governo dos Estados Unidos e da mídia. Ao verificarmos que essas falas demonstram a Wikileaks como uma ameaça existencial para os Estados Unidos, concluímos que a organização sofreu um processo de securitização.
O Nexo entre Segurança e Desenvolvimento no Brasil e na Dinamarca à Luz da Agenda 2030
Authors: Valentim Isabella Monteiro
Published: August 2020

Este artigo busca analisar a relação entre segurança e desenvolvimento por meio da comparação entre Brasil e Dinamarca considerando os Objetivos de Desenvolvimento Sustentável das Nações Unidas (ODS) da Agenda 2030. Para tanto, serão analisados o Índice de Desenvolvimento Humano (IDH), e oito indicadores sociais: desigualdade de renda, fome, saúde mental, suicídio, felicidade, educação, criminalidade e violência, através de dados estatísticos e bibliografia especializada nos temas. Concluiu-se que segurança e desenvolvimento estão intimamente ligados, que o sucesso na área da educação vai além do montante de investimento feito por um país, e que apesar da Dinamarca configurar um caso de sucesso, ambos os países enfrentam sérias dificuldades em relação à saúde mental da população jovem.
INTERAÇÃO ENTRE OUVINTES E EMISSORAS DE RÁDIO POR MEIO DAS MÍDIAS SOCIAIS: o caso da Região Celeiro (RS)
Authors: TRENTIN Lidia Paula
Published: August 2020

Parte da investigação de doutorado, cujos objetos empíricos são as rádios Província 100.7 FM, Querência 89.7 FM e Difusora AM 1350, localizadas na Região Celeiro do Rio Grande do Sul, a presente pesquisa busca identificar as possibilidades de interação entre público e emissoras tendo em vista as mídias sociais dessas rádios. Para tanto, foi realizada uma análise de conteúdo das redes sociais e aplicativos para smartphone, bem como verificação das possibilidades de interação nos sites das três emissoras. Os resultados demonstram que os sites e aplicativos não oferecem possibilidade de interação, é possível apenas ouvir a programação, para contatar as emissoras é necessário utilizar o WhatsApp, e-mail, ligação telefônica ou redes sociais, principalmente o Facebook, que é a rede que mais gera engajamento dos ouvintes das três emissoras. Quanto a responsividade, nenhuma das rádios reage ou responde aos comentários feitos em suas páginas, entretanto, aqueles relacionados à programação, programas e locutores são mencionados ao vivo.

Palavras-chave

Rádio; Rádio na Internet; Interação; Região Celeiro; Rio Grande do Sul.