bluuebunny/crossref_metadata_2025 huggingface dataset:
Nigeria’s Bank of Agriculture: An Agenda for Organizational Renewal
Authors: Adeniyi Adetunji
Published: May 2021

Bank of Agric (BoA) was establish as a special purpose specialized financial institution to provide agricultural loans to deserving customers as a way to promoting access to affordable credit facilities to segments of the Nigerian society that have little access to the services of conventional banks while accepting savings deposits from customers and encouraging banking habits at the grass-roots. However, the performance of the bank has been below expectation because it has not fulfilled purpose. In a country like Nigeria of N200 million population, where agriculture currently provides about 54 per cent of employment and the quest for economic resilience and sustainability is further driving diversification into agribusiness, improving access to agricultural credit, is imperative. It is against this background that the need to reposition the bank becomes necessary. It is recommended that the bank be partially privatised for access to increased / private capital, while its operations should be modernized and computerized to improve customer convenience and operational efficiency.
Centers for Medicare & Medicaid Services' 2018 Removal of Total Knee Arthroplasty From the Inpatient-only List Led to Broad Changes in Hospital Length of Stays
Authors: Rankin Kelsey A. , Freedman Isaac G. , Rubin Lee E. , Grauer Jonathan N.
Published: May 2021

Introduction:

Centers for Medicare & Medicaid Services (CMS) removed total knee arthroplasty (TKA) from the “inpatient-only” list from January 1, 2018. The impact of this change on actual hospital length of stay (LOS) and patient coding is of interest.

Methods:

Patients undergoing TKA were abstracted from the 2015 to 2018 National Surgical Quality Improvement Program database. Patient characterization as “inpatient” or “outpatient” and actual LOS were assessed. Ordinal and categorical data comparisons were done with Pearson chi-squared tests. Continuous variables were tested for normality, and nonparametric analyses were conducted using the Mann-Whitney test. Significance was set at P < 0.05.

Results:

In total, 125,613 TKA patients from 2017 to 2018 were identified (232,269 TKA patients from 2015 to 2018). Most patients undergoing TKA were of Medicare eligibility (≥65 years old; 60.78% in 2017 and 62.42% in 2018). Overall, LOS decreased significantly from 2017 to 2018 (2.31 ± 1.56 days versus 2.05 ± 1.57 days; P < 0.001), and more patients were discharged the same day (5.09% versus 2.28%; P < 0.001). In 2017, patients were coded as “outpatient” 1.66% of the time (those with LOS = 0 days were 22.85%, LOS = 1 day were 1.80%, LOS = 2 days were 0.79%, and LOS ≥3 days were 0.85%). In 2018, patients were coded as “outpatient” 17.14% of the time (those with LOS = 0 days were 78.2%, LOS = 1 day were 29.75%, LOS = 2 days were 6.96%, and LOS ≥3 days were 3.05%). This represented a significant change for each LOS day (P < 0.001). These results remained true when stratifying by Medicare eligibility (P < 0.001 for those <65 years old and those ≥65 years old).

Discussion:

After the 2018 removal of TKA from the CMS “inpatient-only” list, patients were more likely to be discharged the same day and be considered “outpatients.” Patients with more prolonged LOS and those younger than 65 years were more likely to have been coded as “outpatient” in 2018 compared with 2017. These data demonstrate that national changes in CMS policies can have broad impact on overall practice patterns.

Level of Evidence:

Retrospective cohort study.
The Competitive Orthopaedic Trauma Fellowship Applicant: A Program Director's Perspective
Authors: Shaath M. Kareem , Warner Stephen J. , Kellam James F. , Achor Timothy S.
Published: May 2021

Introduction:

In 2018, orthopaedic trauma had the lowest match rate among orthopaedic subspecialties. The purpose of this study was to determine the importance of factors evaluated by orthopaedic trauma fellowship directors when ranking applicants after the interview.

Methods:

An electronic survey was submitted to fellowship directors and consisted of 16 factors included in a fellowship application. Respondents were asked to rate the importance of these factors for applicants they interviewed on a 1 to 5 Likert scale, with 1 being not at all important and 5 being critical.

Results:

Thirty-seven fellowship directors responded (63.8%). The highest-rated factor was the applicant interview (mean score 4.82), followed by the quality of letters of recommendation (4.69), personal connections made to the applicant (3.89), and potential to be leader (3.86). Fellowship directors at academic programs rated interest in an academic career (P = 0.003), research experience (P = 0.023), and exposure to well-known orthopaedic traumatologists (P = 0.003) higher than their counterparts at private institutions. Programs with more than one fellow rated potential to be a leader higher than programs with one fellow (P = 0.02).

Discussion:

Trainees may use this study when compiling an application to optimize their chances of matching at the program of their choice.
Predictors of the Use of Traditional Medicines in the Universal Health Coverage System in Indonesia
Authors: Sally Rahayu Yen Yen , Araki Tetsuya , Rosleine Dian
Published: May 2021

Background: Indonesia has committed to achieving Universal Health Coverage (UHC) and introduced national health insurance (JKN) to meet that commitment. Despite the increasing availability of healthcare services under the JKN scheme, traditional medicine (TM) continues to be a significant part of healthcare for Indonesians. In the context of the UHC system, this study aims to examine the predictors of TM use among urban and rural communities in Indonesia.

Methods: A cross-sectional survey was conducted using a semi-structured questionnaire targeting urban and rural communities. A total of 926 households were randomly selected to participate in the survey. Multivariate logistic regression analysis was used to identify the significant predictors of TM use.

Results: Multivariate analysis revealed the following variables to be predictive of TM use, namely, rural residence, being more educated, experiencing some health problem, demonstrating ethnomedical knowledge, having a favourable opinion about the safety and efficacy of TM and holistic orientation to health.  On the other hand, working in the formal sector was associated with lower odds of using TM compared to those who were employed in the informal sector.

Conclusion: People’s experience, personal attributes, and attitude towards TM, rather than dissatisfaction with healthcare service, predicted the likelihood of using TM in the UHC system in Indonesia. This finding also implies the underutilisation of JKN services by the insured TM users living in rural areas. Considering the community’s strong preferences for TM, this paper argues that its inclusion in the JKN system may increase the utilisation of the JKN service.
Prevalence and Physical Environmental Conditions as Risk Factor for Pulmonary Tuberculosis in Indonesia 2015
Authors: Perwitasari Dian , Simarmata Oster Suriani , Pangaribuan Lamria , Tejayanti Teti , Lolong Dina Bisara , Kristina Kristina , Long Qian
Published: May 2021

OBJECTIVE: The number of tuberculosis (TB) cases in Indonesia is currently very high, so the analysis is needed to describe the environmental conditions at risk of TB disease. The aim of the study was to look at the prevalence of pulmonary TB in 2013-2014 in Indonesia based on the area of residence of the respondents and to see the relationship between the environmental conditions of the prevalence of TB in Indonesia.

MATERIAL & METHODS: The Prevalence SPTB 2013-2014 was used cross-sectional design with national coverage. Sampling selection used multi-staged cluster sampling in the population aged 15 years and above. The analysis data used SPSS program; first analysis was used bivariate and continuing to multivariate analysis.

RESULT: Tb prevalence rate with bacteriological confirmed was 759 [95% CI: 590, 961] per 100,000 population in aged 15 years and above. The bivariable analysis shown those participant who live at house with floor <8m2/person [95% CI:1,053,1,710] and those participant who lived in house with kitchen was not separated from the main living area in the house [95% CI: 1,034,1,669], that was significant related with TB. In the multivariable model, the density characterized by family members with a floor surface <8m2/person [95% CI: 1,017,1,671]is at risk of developing TB.

CONCLUSION: This study shows that the effect of the physical environment of living in a crowded household can be a risk factor for TB transmission. The other factor might be influence of infection Tb in the community.
Estimating 24 Hour Sodium Urine from Spot Urine: A Correlation Model Among Aged 25-64 in Indonesia
Authors: Rahajeng Ekowati , Kusumawardani Nunik , Rachmawati Rika , Ernawati Fitrah
Published: May 2021

INTRODUCTION: Excess salt intake is known to raise blood pressure and turn increase the risk of cardiovascular disease. Data and information on sodium consumption in Indonesia based is limited, while examination method using 24-hour urine examination is a complex method to apply in population based survey. Objective: to estimate value of spot urinary excretion against 24-hour urine values ​​and correction factors.

METHOD: Validation was carried out through 24-hour urine and spot urine examination, in 423 individual aged 25-65 years in t Kebun Kelapa Village, Bogor City, Indonesia in 2017. Urine sodium examination method was carried out by laboratory examination inductively coupled plasma optical emission spectrometry (ICP-OES). Accuracy and precision are valued by paired test correlations and mean differences. The coefficient of determination (R Square) of is calculated for sodium intake estimation and correction factors.

RESULTS: The morning value of sodium spot urine has better precision and a stronger correlation with the 24-hour sodium urine than the afternoon spot urine. The difference in average morning sodium urine with 24-hour urine sodium according to age and sex was not significantly different (t test 0.30 and p = 0.77), had a positive and moderate correlation (paired r = 0.50 and p = 0.00). The average difference between the estimated evening urine sodium spot was different (t test = 7.32 and p = 0.00), and the correlation was very weak (r = 0.25; p = 0.00).

CONCLUSION: The urine content / sodium spot level was accurate to estimate urine sodium value / content 24 hours.
Perspectives of Self-Care Experiences of Aging Individuals Living Independently: A Focused Ethnography in the Community Setting
Authors: Vivarakanon Phatchanun
Published: May 2021

Globally, aging individuals who live independently facing various problems in maintaining their health and well-being. Understanding the capability of personal well-being is an important consideration in promoting healthy behaviors and lifestyles in aging individuals. This paper aimed to more deeply explore, from self-care experiences of aging individuals living independently in the community, from their perspective. The study used the inductive approach of focused ethnography which is based on Orem’s Theory of Self-Care. Data collection consisted of participant observation with field notes and semi-structured interviews with 25 aging individuals living independently in the northern part of Thailand. Three themes were followed as protocol of the data collection plan and used the identification and classification of transcription, coding, and thematic analysis as perspectives of self-care experiences of aging individuals living independently in the community setting: 1) continuing habits of healthcare practices, 2) maintaining positive emotional adaptation, 3) and having reasonable social and life adjustments. These themes exemplified the practice of activities that aging individuals initiated and performed as their daily and routine activities with the intention of maintaining life health and well-being. Consideration of aging individuals living independently self-care experiences assisted nurses and provided greater perspectives in providing actual needs and reduced resources of nursing care and healthcare system.
Knowledge, Attitudes, and Practices (KAP) Regarding Physical Activity among Healthcare Professionals (HCPs) in Suva, Fiji
Authors: Bako Keresi Rokorua , Mohammadnezhad Masoud , Khan Sabiha
Published: May 2021

BACKGROUND: More than 60% of the world’s population is not physically active. Physical inactivity affects all sectors of the population including among healthcare professionals (HCPs). The objective of this study was to determine the level of knowledge, attitudes and practices (KAP) regarding the concept, benefits and health consequences of physical activity (PA) among HCPs in Suva, Fiji.

METHODS: This quantitative, cross-sectional study was conducted among HCPs in Suva, Fiji between 1 July 2017 and 22 September 2017. All available HCPs including doctors, nurses and paramedics who were willing to take part in the study were included. A validated self-administered questionnaire was used to assess the level of KAP regarding PA. Data was analysed with Statistical Package for the Social Sciences (SPSS) 25.

RESULTS: 126 HCPs participated in this study with the majority being female (73.8%), in the age range of 33 – 42 years (47.6%), married (81.7%), from the nursing profession (54.0%) and within 0-5 years of experience (27.0%). The results showed that most of the participants (96.8%) had a high level of knowledge, positive attitudes (100%) and good practice (95%) regarding PA.

CONCLUSION: Although the study participants had high levels of knowledge and positive attitudes towards PA, it is important to promote their practice. Using tailored behavioural change theories that focus on perceived benefits and barriers of PA may help decision-makers to promote PA in the workplace and among HCPs in Fiji.
AN ERROR ANALYSIS FOR THE MIDPOINT METHOD
Authors: ARGYROS IOANNIS K.
Published: May 2021

We approximate zeros of nonlinear operator equations in Banach space setting using Newton-Kantrorvich assumptions and the majorant theory for the midpoint method.
The Feasibility and Tolerability of Using Inspiratory Muscle Training with Adults Discharged from the Hospital with Community-Acquired Pneumonia
Authors: Pick Harry , Faghy Mark , Creswell Gareth , Ashton Deborah , Bolton Charlotte , McKeever Tricia , Lim Wei , Bewick Thomas
Published: May 2021

Introduction: Patients experience substantial morbidity following discharge from hospital and during recovery from communi-ty-acquired pneumonia (CAP). Inspiratory muscle training (IMT) has demonstrated improved functional capacity and reduced patient-reported symptoms. To date the safety and tolerability of these methods have not been determined in CAP patients recovering following hospitalization. Accordingly, this study aimed to assess the safety and tolerability of IMT in adults discharged from hospital with CAP. Material and methods: Participants received an IMT device (POWERbreathe KHP2) and completed 9-weeks IMT training with weekly follow-up. Frequency (twice daily) and load (50% PImax) were fixed throughout, but training volume increased incrementally (2-week habituation phase, 7-week training phase). Primary outcomes of interest included IMT safety and tolerability. Results: Twenty-two participants were recruited; 16 were male, mean age 55.2 years (range 27.9–77.3). From 1183 possible training days, side effects were reported on 15 occasions by 10 individual participants. All reported side-effects were assessed as grade 1 and did not prevent further training. Participant-reported IMT acceptability was 99.4%. Conclusion: Inspiratory muscle training is safe and tolerable in patients following hospitalisation for CAP. Patient satisfaction with IMT is high and it is viewed by patients as being helpful in their recovery. Distinguishing CAP-related symptoms and device-related side effects is challenging. Symptom prevalence declined during follow-up with concurrent improvements in spirometry observed. Further research is required to determine the efficacy of IMT interventions following CAP and other acute respiratory infections.
A Clinical Profile and Factors Associated with Severity of the Disease Among Polish Patients Hospitalized Due to COVID-19—An Observational Study
Authors: Stachura Tomasz , Celejewska-Wójcik Natalia , Polok Kamil , Górka Karolina , Lichołai Sabina , Wójcik Krzysztof , Krawczyk Jacek , Kozłowska Anna , Przybyszowski Marek , Włoch Tomasz , Górka Jacek , Sładek Krzysztof
Published: May 2021

Introduction: The coronavirus disease 2019 (COVID-19) is one of the greatest clinical challenges of the last decades. Clinical factors associated with severity of the disease remain unclear. The aim of the study was to characterize Polish patients hospitalized due to COVID-19 and to evaluate potential prognostic factors of severe course of the disease. Material and methods: An observational study was conducted from March to July 2020 in the Pulmonology and Allergology Department of the University Hospital in Kraków, Poland. Consecutive patients with confirmed SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) infection were enrolled, and data about past medical history, signs and symptoms, laboratory results, imaging studies results, in-hospital management and outcomes was prospectively gathered. Results: The study sample comprised 100 patients at the mean age of 59.2 (SD 16.1) years among whom 63 (63.0%) were male. Among them 10 (10.0%) died, 47 (47%) presented respiratory failure, 15 (15.0%) were transferred to the intensive care unit, 17 (17.0%) developed acute kidney injury, 7 (7.0%) had sepsis and 10 (10.0%) were diagnosed with pulmonary embolism. Multivariable analysis revealed age (OR 1.1; 95% CI 1.01–1.15), body mass index (BMI; OR 1.24; 95% CI 1.01–1.53), modified early warning score (MEWS; OR 3.95; 95% CI 1.48–12), the highest d-dimer value (OR 1.73; 95% CI 1.03–2.9) and lactate dehydrogenase (LDH; OR 1.16; 95% CI 1.03–1.3) to be associated with severe course of COVID-19. Conclusion: This observational study showed that almost half of hospitalized patients with COVID-19 developed respiratory failure in the course of the disease. Increasing age, BMI, MEWS, d-dimer value and LDH concentration were associated with the severity of COVID-19.
Predictors of Mortality in Patients with Severe COVID-19 Pneumonia—A Retrospective Study
Authors: M Mahendra , Nuchin Abhishek , Kumar Ranjith , S Shreedhar , Mahesh Padukudru
Published: May 2021

Introduction: The novel coronavirus pandemic has caused significant mortality throughout the world. This study was done as there is scarce data on mortality predictors in severe COVID-19 pneumonia patients admitted to ICU in the Indian population. Material and methods: A retrospective study was conducted on COVID-19 pneumonia patients admitted to tertiary care center during June–October 2020. The records of patients admitted to ICU were collected and data included demography, symptoms, comorbidites and vital parameters. Laboratory parameters included complete hemogram, random blood sugar, S.Ferritin, S.LDH, renal function test, liver function test. Treatment-associated information such as the use of remdesivir, timing of initiating rem-desivir after the symptom onset, the use of steroids, use of anticoagulants, use of HFNC, NIV, ventilator were collected. 30 days mortality data post-discharge was collected via telephonic interview. Results: 4,012 confirmed cases of COVID-19 were admitted to hospital, of which 560 (13.95%) with severe pneumonia were included in the study. Mean age was 57.75 ± 13.96 years. The mortality rates were 54.64% among severe COVID-19 cases and 5% among mild to moderate COVID-19 cases. The Cox multinominal regression analysis identified SpO2/FiO2 < 400, age > 50 years, duration of symptom > 4 days, serum ferritin > 450 µg/L, respiratory rate > 23/min, the presence of comorbidities and non-usage of remdesivir were independently associated with increased mortality. Mortality rate at 30 days was 56.60%. Conclusion: Severe COVID-19 pneumonia is associated with very high mortality, especially in a resource-constrained setting. The use of remdesivir may have to be considered early in the course of disease to prevent excess mortality related to COVID-19.
The Relationship Between the Severity and Mortality of SARS-CoV-2 Infection and 25-hydroxyvitamin D Concentration—A Metaanalysis
Authors: Oscanoa Teodoro , Amado Jose , Vidal Xavier , Laird Eamon , Ghashut Rawia , Romero-Ortuno Roman
Published: May 2021

Introduction: There is increasing scientific interest in the possible association between hypovitaminosis D and the risk of SARS-CoV-2 infection severity and/or mortality. Objective: To conduct a metanalysis of the association between 25-hydroxyvitamin D (25(OH)D) concentration and SARS-CoV-2 infection severity or mortality. Material and methods: We searched PubMed, EMBASE, Google scholar and the Cochrane Database of Systematic Reviews for studies published between December 2019 and December 2020. Effect statistics were pooled using random effects models. The quality of included studies was assessed with the Newcastle–Ottawa Scale (NOS). Targeted outcomes: mortality and severity proportions in COVID-19 patients with 25(OH)D deficiency, defined as serum 25(OH)D < 50 nmol/L. Results: In the 23 studies included (n = 2692), the mean age was 60.8 (SD ± 15.9) years and 53.8% were men. Results suggested that vitamin 25(OH)D deficiency was associated with increased risk of severe SARS-CoV-2 disease (RR 2.00; 95% CI 1.47–2.71, 17 studies) and mortality (RR 2.45; 95% CI 1.24–4.84, 13 studies). Only 7/23 studies reported C-reactive protein values, all of which were > 10 mg/L. Conclusions: 25(OH)D deficiency seems associated with increased SARS-CoV-2 infection severity and mortality. However, findings do not imply causality, and randomized controlled trials are required, and new studies should be designed to determine if decreased 25(OH)D is an epiphenomenon or consequence of the inflammatory process associated with severe forms of SARS-CoV-2. Meanwhile, the concentration of 25(OH)D could be considered as a negative acute phase reactant and a poor prognosis in COVID-19 infection.
The Role of Screening Questionnaires in the Assessment of Risk and Severity of Obstructive Sleep apnea—Polysomnography Versus Polygraphy
Authors: Małolepsza Aleksandra , Kudrycka Aleksandra , Karwowska Urszula , Hoshino Tetsuro , Wibowo Erik , Böjti Péter , Białas Adam , Kuczyński Wojciech
Published: May 2021

Obstructive sleep apnea (OSA) is a disease of significant importance, which may lead to numerous severe clinical consequences. The gold standard in the diagnosis of this sleep-related breathing disorder (SRBD) is polysomnography (PSG). However, due to the need for high expertise of staff who perform this procedure, its complexity, and relatively low availability, some simpler substitutes have been developed; among them is polygraphy (PG), which is most widely used. Also, there is a variety of questionnaires suitable to assess the pre-test probability and severity of OSA. The most frequently used ones are the STOP-BANG questionnaire (SBQ), NoSAS questionnaire, and Berlin questionnaire (BQ). However, they have different sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) when being used in various populations. The aim of this study is to provide a concise and clinically-oriented review of the most frequently used questionnaires, with special attention to its strengths and limitations. Moreover, we discuss whether PSG or PG would be more preferred for confirming OSA diagnosis with the highest likelihood.
Non-surgical Treatment of Coccygodynia with Manual Therapy - Case Report
Authors: Dampc Bogumiła , Słowiński Krzysztof
Published: May 2021

Introduction: Coccygodynia - pain in the coccyx and tissues lying in its immediate vicinity is a known problem, however, little examined and assessed. The problem affects only 1% of people with spinal problems. This may be for many reasons - from organic to functional, to a number of extra-local causes.

Introduction: Coccygodynia - pain in the coccyx and tissues lying in its immediate vicinity is a known problem, however, little examined and assessed. The problem affects only 1% of people with spinal problems. This may be for many reasons - from organic to functional, to a number of extra-local causes.

Study aim: The aim of the study is to present the diagnostic process and course of non-surgical - physiotherapeutic treatment - of a 12-year-old boy with idiopathic coccyx pain syndrome using the methodology of manual therapy proposed by Rakowski, with an assessment of immediate and final treatment points.

Materials and methods: Research was carried out among a group of 13,793 subjects at the Manual Therapy Centre in Sierosław near Poznań. From this group, individuals with tailbone pain were extracted, which accounts for 1.15% of the remaining participants. The following case report is a representative example selected from the above group. Diagnostics were based on subjective assessment and medical examination (performed at a children's hospital), including medical examination with access through the anus and physiotherapeutic manual examination.

Results and conclusions: Coccygodynia requires detailed imaging and functional diagnostics, with particular attention being paid to the structures directly related to the sacro-coccygeal region, as well as to the place lying outside the area of the experienced ailments. The solution to idiopathic pain syndrome in the coccygeal region is targeted manual therapy, taking selected elements of the musculoskeletal structures into account. The described procedure is in line with the methods created by Rakowski, along with local and non-local therapeutic interventions. In the described case, total alleviation of the ailments was achieved, both in short-term assessment and 3 years after completion of treatment.
Comparison of Three Different Doses of Dexmedetomidine Added to Bupivacaine in Ultrasound-Guided Transversus Abdominis Plane Block; A Randomized Clinical Trial
Authors: Talebi Gilda , Moayeri Hassan , Rahmani Khaled , Nasseri Karim
Published: May 2021

Background: Adding dexmedetomidine to bupivacaine has been shown to prolong the analgesic effects of the transversus abdominis plane (TAP) block. However, the optimal dose of this adjuvant drug is unclear. Objectives: Identifying optimal doses of dexmedetomidine added to bupivacaine in the TAP block. Methods: In this randomized controlled trial, 86 patients candidate for elective open inguinal herniorrhaphy under spinal anesthesia were divided randomly into three groups; low (L), medium (M), and high (H) dose of dexmedetomidine, that finally 80 cases ended the study and were analyzed. At the end of the surgery, the patients underwent ultrasound-guided TAP block. In all patients of the three groups, the analgesic base of the block was 20 mL bupivacaine 0.125% that was supplemented with 0.5, 1, or 1.5 µ/kg of dexmedetomidine in groups L, M, and H, respectively. Results: The maximum duration of the block was 4 hours in group L and 8 hours in groups M and H. None of the patients needed to receive analgesic at 0, 2, and 24 hours after the block. The dose of analgesic required in the first 8 hours of the block in groups M and H was less than in group L (P < 0.02). Patients in groups H and M were more satisfied with the block (P < 0.01) and experienced less pain compared with group L (P < 0.01). Drowsiness and sedation were observed in patients up to 4 hours after the TAP block, which was dependent on the dexmedetomidine dose (P < 0.01). Conclusions: Based on our results, the optimal dose of supplemental dexmedetomidine could be 1 µ/kg in the TAP block.
In the News
Authors: Free David
Published: May 2021

Welcome to the May 2021 issue of C&RL News. We open this month’s issue with latest installment of our Perspectives on the Framework column. Christopher Sweet of Illinois Wesleyan University advocates for increasing the focus on social justice in the Framework for Information Literacy in his article “Overdue.”
You keep using that word: Slaying the dragon of reference desk statistics
Authors: Rabinowitz Celia
Published: May 2021

It’s that time of the year again. You know, that time when we are chasing down our IPEDS/ACRL numbers for the dreaded annual reports. Even with some helpful changes over the past few years, I continue to have questions about the value of at least some of the information we are all asked to provide. Some important trends can be clearly tracked. Circulation of print/physical materials has been declining steadily overall and continues to do so. Why? Ask a roomful of librarians and you will undoubtedly get many different explanations, and the reasons are a combination of many of those. Expenditures on those print/physical items is also declining in many academic libraries.
Internet Reviews
Authors: Roberts Joni R. , Drost Carol A.
Published: May 2021

AllsidesMargaret Herrick Library Digital CollectionNational Eating Disorders Association
Fast Facts
Authors: Pattillo Gary
Published: May 2021

Distance educationDigestible newsBook publishing industry 2020Top education appsHandwriting helps learning
Adapting non-invasive human recordings along multiple task-axes shows unfolding of spontaneous and over-trained choice
Authors: Takagi Yu , Hunt Laurence Tudor , Woolrich Mark W , Behrens Timothy EJ , Klein-Flügge Miriam C
Published: May 2021

Choices rely on a transformation of sensory inputs into motor responses. Using invasive single neuron recordings, the evolution of a choice process has been tracked by projecting population neural responses into state spaces. Here, we develop an approach that allows us to recover similar trajectories on a millisecond timescale in non-invasive human recordings. We selectively suppress activity related to three task-axes, relevant and irrelevant sensory inputs and response direction, in magnetoencephalography data acquired during context-dependent choices. Recordings from premotor cortex show a progression from processing sensory input to processing the response. In contrast to previous macaque recordings, information related to choice-irrelevant features is represented more weakly than choice-relevant sensory information. To test whether this mechanistic difference between species is caused by extensive over-training common in non-human primate studies, we trained humans on >20,000 trials of the task. Choice-irrelevant features were still weaker than relevant features in premotor cortex after over-training.
Coronary plaque composition influences biomechanical stress and predicts plaque rupture in a morpho-mechanic OCT analysis
Authors: Milzi Andrea , Lemma Enrico Domenico , Dettori Rosalia , Burgmaier Kathrin , Marx Nikolaus , Reith Sebastian , Burgmaier Mathias
Published: May 2021

Plaque rupture occurs if stress within coronary lesions exceeds the protection exerted by the fibrous cap overlying the necrotic lipid core. However, very little is known about the biomechanical stress exerting this disrupting force. Employing optical coherence tomography (OCT), we generated plaque models and performed finite-element analysis to simulate stress distributions within the vessel wall in 10 ruptured and 10 non-ruptured lesions. In ruptured lesions, maximal stress within fibrous cap (peak cap stress [PCS]: 174 ± 67 vs. 52 ± 42 kPa, p<0.001) and vessel wall (maximal plaque stress [MPS]: 399 ± 233 vs. 90 ± 95 kPa, p=0.001) were significantly higher compared to non-ruptured plaques. Ruptures arose in the immediate proximity of maximal stress concentrations (angular distances: 21.8 ± 30.3° for PCS vs. 20.7 ± 23.7° for MPS); stress concentrations excellently predicted plaque rupture (area under the curve: 0.940 for PCS, 0.950 for MPS). This prediction of plaque rupture was superior to established vulnerability features such as fibrous cap thickness or macrophage infiltration. In conclusion, OCT-based finite-element analysis effectively assesses plaque biomechanics, which in turn predicts plaque rupture in patients. This highlights the importance of morpho-mechanic analysis assessing the disrupting effects of plaque stress.
The role of sigma 1 receptor in organization of endoplasmic reticulum signaling microdomains
Authors: Zhemkov Vladimir , Ditlev Jonathon A , Lee Wan-Ru , Wilson Mikaela , Liou Jen , Rosen Michael K , Bezprozvanny Ilya
Published: May 2021

Sigma 1 receptor (S1R) is a 223-amino-acid-long transmembrane endoplasmic reticulum (ER) protein. S1R modulates activity of multiple effector proteins and is a well-established drug target. However, signaling functions of S1R in cells are poorly understood. Here, we test the hypothesis that biological activity of S1R in cells can be explained by its ability to interact with cholesterol and to form cholesterol-enriched microdomains in the ER membrane. By performing experiments in reduced reconstitution systems, we demonstrate direct effects of cholesterol on S1R clustering. We identify a novel cholesterol-binding motif in the transmembrane region of human S1R. Mutations of this motif impair association of recombinant S1R with cholesterol beads, affect S1R clustering in vitro and disrupt S1R subcellular localization. We demonstrate that S1R-induced membrane microdomains have increased local membrane thickness and that increased local cholesterol concentration and/or membrane thickness in these microdomains can modulate signaling of inositol-requiring enzyme 1α in the ER. Further, S1R agonists cause disruption of S1R clusters, suggesting that biological activity of S1R agonists is linked to remodeling of ER membrane microdomains. Our results provide novel insights into S1R-mediated signaling mechanisms in cells.
Integrative transcriptomic analysis of tissue-specific metabolic crosstalk after myocardial infarction
Authors: Arif Muhammad , Klevstig Martina , Benfeitas Rui , Doran Stephen , Turkez Hasan , Uhlén Mathias , Clausen Maryam , Wikström Johannes , Etal Damla , Zhang Cheng , Levin Malin , Mardinoglu Adil , Boren Jan
Published: May 2021

Myocardial infarction (MI) promotes a range of systemic effects, many of which are unknown. Here, we investigated the alterations associated with MI progression in heart and other metabolically active tissues (liver, skeletal muscle, and adipose) in a mouse model of MI (induced by ligating the left ascending coronary artery) and sham-operated mice. We performed a genome-wide transcriptomic analysis on tissue samples obtained 6- and 24 hr post MI or sham operation. By generating tissue-specific biological networks, we observed: (1) dysregulation in multiple biological processes (including immune system, mitochondrial dysfunction, fatty-acid beta-oxidation, and RNA and protein processing) across multiple tissues post MI and (2) tissue-specific dysregulation in biological processes in liver and heart post MI. Finally, we validated our findings in two independent MI cohorts. Overall, our integrative analysis highlighted both common and specific biological responses to MI across a range of metabolically active tissues.
Enhanced excitability of cortical neurons in low-divalent solutions is primarily mediated by altered voltage-dependence of voltage-gated sodium channels
Authors: Martiszus Briana J , Tsintsadze Timur , Chang Wenhan , Smith Stephen M
Published: May 2021

Increasing extracellular [Ca2+] ([Ca2+]o) strongly decreases intrinsic excitability in neurons but the mechanism is unclear. By one hypothesis, [Ca2+]o screens surface charge, reducing voltage-gated sodium channel (VGSC) activation and by another [Ca2+]o activates Calcium-sensing receptor (CaSR) closing the sodium-leak channel (NALCN). Here we report that neocortical neurons from CaSR-deficient (Casr-/-) mice had more negative resting potentials and did not fire spontaneously in reduced divalent-containing solution (T0.2) in contrast with wild-type (WT). However, after setting membrane potential to −70 mV, T0.2 application similarly depolarized and increased action potential firing in Casr-/- and WT neurons. Enhanced activation of VGSCs was the dominant contributor to the depolarization and increase in excitability by T0.2 and occurred due to hyperpolarizing shifts in VGSC window currents. CaSR deletion depolarized VGSC window currents but did not affect NALCN activation. Regulation of VGSC gating by external divalents is the key mechanism mediating divalent-dependent changes in neocortical neuron excitability.
The Comparative Effect of Dynamic and Negotiated Assessment on EFL learners’ Writing Complexity and Fluency
Authors: Sardarianpour Shirin , Kolahi Sholeh
Published: May 2021

The purpose of the present study was to investigate the comparative effect of dynamic and negotiated assessment on EFL learners’ writing complexity and fluency. To this end, 72 female intermediate EFL participants, selected from a larger group of 103 learners based on their performances on a piloted PET, in Tak language institute in Dezfoul, Iran participated in the present study and received either dynamic assessment, negotiated assessment, or traditional instruction during a term. Both of the experiments were process-oriented; however, in the dynamic assessment, the negotiation was done through teacher’s provision of feedback wherein the negotiated assessment group peer-negotiation was encouraged. The participants’ writing complexity and fluency were measured both before and after the instruction through essay writing pre-treatment test and posttest in accordance with Larsen-Freeman’s (2006) T-Unit protocol. A Multivariate Analysis of Variance (MANOVA) was run on the posttest scores to test the null hypotheses of the study, the results of which indicated that while dynamic assessment was significantly effective in improving writing complexity (p = 0.007 < 0.05), negotiated assessment yielded significantly better results in boosting writing fluency compared to the results obtained from both control (p = 0.000 < 0.05) and dynamic assessment groups (p = 0.042 < 0.05). Nevertheless, dynamic assessment did not show significantly better results in comparison to negotiated assessment in improving writing complexity (p = 0.084 > 0.05). Learners, teachers, and syllabus designers who are engaged in the process of language pedagogy may use these results. Depending on the focus of their learning, i.e., fluency or complexity, they may choose the optimal choice between these two types of assessment.
Universal Grammar: Arguments for its Existence
Authors: Hanoon Umarlebbe Jameela , Binti Mat Said Seriaznita
Published: May 2021

The first part of this paper discusses the rationale for universal grammar (UG) theory to explain first language acquisition. It also illustrates the issues of language acquisition Chomsky argued which could not be supported by behaviourist theories and shows how Chomsky proposed a solution to this problem through his theoretical model of universal grammar. The next part outlines this theory’s key tenets, arguing that these principles must be an innate endowment of the human mind. Moreover, the study illustrates specific examples of grammatical phenomena that universal grammar seeks to explain. Lastly, it shows that certain distinct grammatical features are linked and that these connections can be explained within the Universal Grammar theoretical framework. The only reasonable explanation for the first language learning needs only limited linguistic exposure to activate them and set criteria for the language being learned for children whose minds have already been wired with essential language concepts.
An Exploration of Factors Influencing Teachers’ Attitudes toward the Use of Information and Communication Technology (ICT) in Classroom Practice A Case Study of Secondary School EFL Teachers in the Western District of Chlef , Algeria
Authors: Makhlouf Kouider , Bensafi Zoulikha
Published: May 2021

The use of Information and Communication Technology (ICT) in the teaching and learning process has been the subject of extensive research in the past few decades. Many studies have discussed the benefits of ICT for teachers and learners. However, little is known about the main factors that influence teachers’ attitudes toward the use of ICT in their teaching practices. This study aimed to explore the attitudes of secondary school EFL teachers in the Western District of Chlef toward ICT use in Algeria. Additionally, the study attempted to investigate the relationship between teachers’ computer attitudes and five independent variables: personal characteristics, computer attributes, cultural perceptions, computer competence, and computer access. Mixed methods research was used to combine both quantitative and qualitative research methods. A questionnaire and semi-structured interview were used in order to collect the data. Both descriptive and inferential statistics as well as content analysis were conducted to analyse the data. The findings indicated that EFL teachers held positive attitudes toward ICT in education. There were statistically significant positive correlations between teachers’ attitudes toward ICT and the five aforementioned independent variables. It was also found that age and academic qualification had negatively correlated with attitudes. The results of this study give meaningful insights for educational practitioners and policy-makers in relation to the implementation of ICT for teaching and learning in the classroom. Finally, the study presented some implications for policy and practice and recommendations for further research that will enhance teachers’ use of ICT in their teaching practices.
An Investigation of the Relationship between Reading Comprehension, Vocabulary Knowledge, and English Language Proficiency Level of Saudi EFL Learners
Authors: Suleiman Al Qunayeer Huda
Published: May 2021

The present study is an attempt to explore the relationship between the breadth (the number of words known) and the depth of vocabulary knowledge (the richness of word knowledge) (the richness of word knowledge), and reading comprehension of EFL learners in an English as a foreign language (EFL) context. Furthermore, it tries to find the effect of language proficiency level of learners on the breadth and the depth of lexical vocabulary and reading comprehension of Saudi EFL learners. The participants of the study were seventy-five intermediate and advanced level majoring in English Translation at Qassim University in KSA. The level of language proficiency of participants had been checked through an OPT by the department in advance. To collect the relevant data, two tests measuring breadth and depth of vocabulary knowledge were administered to all participants. They also received a reading comprehension test in which they were asked to read the passages and answer some multiple-choice questions. The findings obtained from the analysis of the data indicated that there is a significant relationship between breadth and depth of vocabulary knowledge and Saudi advanced/intermediate EFL learner’s reading comprehension performance totally. The results further revealed that both dimensions of vocabulary knowledge are positively correlated, that is, those learners who had large vocabulary size had a deeper knowledge of the words, too. The results further showed that language proficiency level of learners have an effect on Saudi EFL learners’ reading performance and vocabulary knowledge. These results confirm the importance and the value of developing students‟ breadth and depth of vocabulary knowledge in EFL classrooms.
The Utilization of Animation in the Theory of Procedure Text Writing for Vi-Grade SD Methodist-2 Medan Students
Authors: Maya Yuniarti , Saragih Erikson
Published: May 2021

This study was motivated by the lack of animation utilization by VI-grade teachers in teaching the theory of procedure text writing. Students are not motivated by the absence of animated media. Therefore, the animation is needed in learning the theory of procedure text writing. This study was included in research and development type and two cycle’s classroom action research. This study was carried out in SD Methodist 2 Medan from July 2020 to August 2020. In small group testing, the subjects were 10 random VI-grade from VI A, VI B, VI C, VI D, and VI E. In large group testing, the subjects were 20 random VI-grade students from VI A, VI B, VI C, VI D, and VI E. In classroom action research, the subjects were 29 VI E students. Several tests on material feasibility, media feasibility, and student responses were carried out. The results showed 89.32% (very feasible) which means animated video as the learning media was very effective for the learning process. After very feasible category was obtained in large group testing, then product dissemination in classroom action research was carried out. Based on the results, in Cycle I, 13 students (44.82%) met the passing grade, while 16 students (55.18%) failed. The average grade was 70.52 while the passing grade was 76, then Cycle II was needed. In Cycle II, 25 students (86.20%) met the passing grade, while 4 students (13.80%) failed. The average grade was 85.69. This means animated video as learning media innovation had a significant influence in learning the theory of procedure text writing on Indonesian language subject. In accordance with these results, as a learning medium, the findings in this study reveal that animated videos are able to develop effective learning patterns in the classroom.
Role of the CEFR and English Teaching in Thailand: A Case Study of Rajabhat Universities
Authors: Charttrakul Kanjana , Damnet Anamai
Published: May 2021

In 2016, Thai Ministry of Education (MOE) has announced the Common European Framework of Reference for Languages or the CEFR (Council of Europe, 2001) as a guideline for teachers in primary and secondary schools. This has inevitably affected Rajabhat Universities (RUs) in the country that have major roles and responsibilities in producing pre-service English teachers. This paper presents the results of an investigation of English teachers’ perceptions at Rajabhat universities in Bangkok and suburban areas. Participants were 67 teachers in total. A mixed-methods approach was employed for data collection. Research tools are a set of questionnaire and an individual semi-structured interview. An interview was conducted with 6 teachers in 6 RUs, each was purposively selected. Data analysis employed frequency, means, and standard deviation, while Grounded theory (Strauss & Corbin, 1999) was used for interview data analysis. Findings indicate the participants mostly agreed with the MOE’s launching the CEFR policy and reflected they could apply the CEFR as a guideline in teaching and learning management. However, data from the in-depth interview revealed both advantages and disadvantages of the CEFR. This study might be a kind of mirror for policy makers and practitioners at both policy and classroom pedagogy levels who advocate the CEFR policy in Thailand.