bluuebunny/crossref_metadata_2025 huggingface dataset:
What Is Justified Group Belief?
Authors: Lackey Jennifer
Published: August 2016

This essay raises new objections to the two dominant approaches to understanding the justification of group beliefs—inflationary views, where groups are treated as entities that can float freely from the epistemic status of their members’ beliefs, and deflationary views, where justified group belief is understood as nothing more than the aggregation of the justified beliefs of the group's members. If this essay is right, we need to look in an altogether different place for an adequate account of justified group belief. From these objections emerges the skeleton of the positive view that this essay goes on to develop and defend, called the group epistemic agent account: groups are epistemic agents in their own right, with justified beliefs that respond to both evidence and normative requirements that arise only at the group level but that are nonetheless importantly constrained by the epistemic status of the beliefs of their individual members.
Atg9A trafficking through the recycling endosomes is required for autophagosome formation
Authors: Imai Kenta , Hao Feike , Fujita Naonobu , Tsuji Yasuhiro , Oe Yukako , Araki Yasuhiro , Hamasaki Maho , Noda Takeshi , Yoshimori Tamotsu
Published: September 2016

Autophagy is an intracellular degradation pathway conserved in eukaryotes. Among core autophagy-related (Atg) proteins, mammalian Atg9A is the sole multi-spanning transmembrane protein, and both of its N- and C-terminal domains are exposed to the cytoplasm. It is known that Atg9A travels through the trans-Golgi network (TGN) and the endosomal system under nutrient-rich conditions, and transiently localizes to the autophagosome upon autophagy induction. However, the significance of Atg9A trafficking for autophagosome formation remains elusive. Here, we identified sorting motifs in the N-terminal cytosolic stretch of Atg9A that interact with the adaptor protein AP-2. Atg9A with mutations in the sorting motifs could not execute autophagy and was abnormally accumulated at the recycling endosomes. The combination of defects in autophagy and Atg9A accumulation in the recycling endosomes was also found upon the knockdown of TRAPPC8, a specific subunit of the TRAPPIII complex. These results show directly that the trafficking of Atg9A through the recycling endosomes is an essential step for autophagosome formation.
A rare case of septic thrombosis in the inferior vena cava with embolism
Authors: Burkert B. , Majewski H. , Mühlberger D. , Mumme A. , Hummel T. , Regeniter Ph.
Published: September 2016

This paper presents the case of a 61-year-old female patient who complained about exhaustion and fever during curative therapy, a few weeks after hysterectomie and adnexectomy. Antibiotic therapy could only improve these symptoms though only in the short term. Additionally, a venous port, which had been implanted for the purpose of cytoreduction chemotherapy, was suspected of a catheter infection and was removed. However, this did not lead to a substantial improvement of the patient’s general state of health, but ultimately triggered a sepsis, making necessary treatment in intensive care unit. At this stage, the detailed search for the focus of the infection led to the discovery of an infected thrombosis of the inferior vena cava with bilateral septic pulmonal embolisms and with an abscess. Thus, the source of sepsis had to be removed by surgery, a transfemoral thrombectomy was performed and an inguinal arteriovenous fistula was created. The further course of the disease was without complications; the patient could be released into ambulant treatment 24 days after the surgery. The elective sealing of the arteriovenous fistula was carried out 11 months later. In the follow- up, there were no hints for infection; the deep venous system in particular did not indicate any new thrombosis or of residual thrombi, with the tumor follow-up-care showing a complete remission.
The Role of Collaboration in Service Innovation Across Manufacturing and Service Sectors
Authors: Feng Cong , Sivakumar K.
Published: September 2016

This study empirically demonstrates the impact of service innovation on innovation performance for manufacturing and service firms and finds that the effect of service innovation on innovation performance is greater for service firms than manufacturing firms. In addition, the results show that the relationship between the propensity for service innovation and three types of collaboration (vertical, horizontal, and third-party collaboration) is significant. Furthermore, this study finds that vertical and third-party collaborations are more beneficial than horizontal collaboration for service firms. This research advances the discourse on service innovation in two ways. First, it offers a stronger justification for examining and fostering innovation generation in service industries. Second, the findings regarding the comparative impact of collaboration highlight the desirability of stronger collaborations with channel members (whose interests are aligned with the firm) and neutral entities (whose interests are not in conflict with the firm) than with competitors (whose interests are likely not aligned with the focal firm). In short, the research presents a detailed and nuanced view of the antecedents and consequences of service innovation.
An Econometric Study of the Hardwood Sawtimber Stumpage Market in Louisiana
Authors: Parajuli Rajan , Zhang Daowei
Published: August 2016

Although the hardwood timber market is an important segment of the forest industry in the United States, little attention has been paid to modeling hardwood stumpage and lumber markets. Based on the annual data series from 1955 to 2014, we estimate simultaneous demand and supply models of the hardwood sawtimber stumpage market in Louisiana. A permanent structural break in 1993 is detected in the hardwood sawtimber stumpage market, and the modified cointegration test and structural vector error correction approach are used to estimate the demand for and supply of hardwood sawtimber stumpage. The results show that own-price elasticity values in both the demand and the supply equations are inelastic in the long run. Hardwood and softwood sawtimber are found to be substitutes. Moreover, the softwood timber market always leads in the feedback adjustment process and can help predict the hardwood timber price in Louisiana.
O IMPACTO DA CULTURA NO USO DE PRODUTOS COM TECNOLOGIA AGREGADA: ESTUDO COM ADOLESCENTES
Authors: Gonçalves Andressa , Tambosi Silvana Vieira , Mondini Vanessa , Machado Denise Del Pra Netto
Published: September 2016

Esta pesquisa teve como objetivo identificar elementos da cultura que podem influenciar na adoção de inovações tecnológicas por adolescentes do Vale do Itajaí. A abordagem foi quantitativa, com o uso da técnica estatística de Regressão Linear Múltipla. A coleta de dados foi feita com aplicação de 472 questionários. Os resultados indicaram que os adolescentes tendem a confrontar mais as decisões de seus pais, e apresentaram uma tendência ao individualismo e à baixa distância do poder. Ressalta-se que o aspecto medido nesta pesquisa se refere a adoção de inovações tecnológicas e os relacionamentos com os pais e colegas.
COGNIÇÃO E AFETIVIDADE NAS TRAJETÓRIAS EMPREENDEDORAS DAS MULHERES DA CIDADE DO NATAL – RN
Authors: Cortez Ana Eliza Galvão , Ferreira Thaís Barbosa , Ferreira Cristiane de Melo , Araújo Afrânio Galdino
Published: September 2016

Este estudo tem como objetivo geral compreender a influência dos aspectos cognitivos e afetivos nas trajetórias de mulheres empreendedoras na cidade do Natal – Rio Grande do Norte. Norteia-se pelo framework proposto por Nassif, Ghobril e Silva (2010), que considera a dinamicidade do processo empreendedor ao contemplar fatores como características pessoais, sociológicas e ambientais e as diferentes fases pelas quais passa uma organização. Julgou-se oportuno a realização de um estudo qualitativo e para viabilizar a consecução dos objetivos, utilizou-se o método da história oral temática. A pesquisa foi desenvolvida com dez mulheres empreendedoras da cidade do Natal - RN, que estão à frente de empreendimentos de três anos e meio a 30 anos de existência.  A coleta dos dados foi realizada por meio de entrevista semiestruturada, que foi transcrita e analisada utilizando a análise de conteúdo. Os resultados apontam que os aspectos afetivos têm significativa e constante relevância nas ações das empreendedoras em todas as fases de seus empreendimentos e que os aspectos cognitivos se tornam mais influentes à medida que os empreendimentos crescem e se desenvolvem no decorrer da trajetória empreendedora.
The cognitive contribution within the Tunisian venture capital funded firms
Authors: Dziri Houda , Jarboui Anis
Published: August 2016

The present research workâ€™s major objective lies in investigating the scope of the venture capitalistâ€™ cognitive contribution following their financial participation in the company's capital. Conducted on a sample of 70 Tunisian venture capital funded firms, operating up the year 2015, the survey reached findings have proved to reveal well the significant impact this financial intermediation mode appears to have on kindling cognitive resources, in its association with the contractor. Noteworthy, however, is that the cognitive contribution has been discovered to be constrained, in turn, by the venture capital organizationâ€™s proper ownership structure.
Transmutation of the two parameters Rayleigh distribution
Authors: Ullah Ehsan , Shahzad Mirza
Published: September 2016

In this study, transmuted two parameters Rayleigh distribution is proposed using quadratic rank transmutation map. This proposed distribution is more flexible and versatile than two parameters Rayleigh distribution. Some properties of the proposed distribution are derived such as moments, moment generating function, mean, variance, median, quantile function, reliability, and hazard function. The parameter estimation is approached through the method of least square estimation. The th and joint order statistics are also derived for the proposed distribution. The application of proposed model illustrated and compared using real data.
Variational iteration method for studying perihelion precession and deflection of light in General Relativity
Authors: Shchigolev V.K.
Published: August 2016

A new approach in studying the planetary orbits and deflection of light in General Relativity (GR) by means of the Variational iteration method (VIM) is proposed in this paper. For this purpose, a brief review of the nonlinear geodesic equations in the spherical symmetry spacetime and the main ideas of VIM are given. The appropriate correct functionals are constructed for the geodesics in the spacetime of Schwarzschild, Reissner-NordstrÃ¶m and Kiselev black holes. In these cases, the Lagrange multiplier is obtained from the stationary conditions for the correct functionals. Then, VIM leads to the simple problem of computation of the integrals in order to obtain the approximate solutions of the geodesic equations. On the basis of these approximate solutions, the perihelion shift and the light deflection have been obtained for the metrics mentioned above.
Genetic Stock Identification and Relative Contribution of Arctic Char (Salvelinus alpinus) from the Hornaday and Brock Rivers to Subsistence Fisheries in Darnley Bay, Northwest Territories + Supplementary Appendix Tables S1 to S4 (See Article Tools)
Authors: Harris Les N. , Bogsuski David A. , Gallagher Colin P. , Howland Kimberly L.
Published: September 2016

Where anadromous fishes occur in the Canadian Arctic, they provide the mainstay of local subsistence fisheries of varying intensities. Many of these fisheries harvest a mixture of stocks at discrete locations and it is often not known which stocks, specifically, are being harvested and to what extent. In the Darnley Bay area of the Northwest Territories, Arctic char, Salvelinus alpinus, in particular have long provided an important subsistence resource to residents of Paulatuk, and char from two systems (the Hornaday and Brock Rivers) are thought to contribute to the coastal fishery for this species. Genetic mixed-stock analysis (GMA) is routinely applied for resolving stock contributions to such fisheries, yet studies incorporating GMA to understand specifically which stocks are being harvested in the Canadian Arctic, and to what extent, are relatively scarce. In this study, we assayed microsatellite DNA variation among 987 Arctic char from two important coastal subsistence fisheries and several inland sampling locations in the Darnley Bay area to (1) assess the degree of genetic structuring between the Hornaday and Brock Rivers and (2) resolve the proportional contributions of these stocks to coastal mixed-stock fisheries in the region using GMA. Overall, genetic differentiation was relatively high and significant (θ = 0.117; 95% C.I. = 0.097–0.142) among baseline sampling locations. Overall patterns of genetic stock structure also support previous hypotheses that additional life history types (e.g., landlocked or freshwater-resident char, or both) exist in the Hornaday system, as indicated by elevated levels of genetic differentiation between some of our sampling locations. The GMA suggested that, while both river systems contribute to the coastal fishery, catches were dominated by Arctic char from the Hornaday River, which highlights the importance of this system. All told, our results may be relevant to the management of the subsistence fishery in Darnley Bay and for furthering the collective understanding of char biodiversity and life history variation in the Canadian Arctic.
Seeing through transparency in education reform: Illuminating the “local”
Authors: Koyama Jill , Kania Brian
Published: August 2016

Utilizing “assemblage,” a notion associated with Actor-Network Theory (ANT), we explore what discourses of transparency can, and cannot, accomplish in a network of education reform that includes schools, government agencies, and community organizations. Drawing on data collected between July 2011 and March 2013 in an ethnographically-informed case study, we interrogate the ways in which notions of transparency illuminate, and also conceal, information, as well as reveal how they reorder power dynamics and relationships, impacting what it legitimized as reform in a city in Western New York. We problematize the linkages between the political conditions in which mandatory transparency and accountability in schooling become connected to voluntary transparency in local education reform, and we examine the investment made by schools and reform organizations in using transparency as a proxy for meeting accountability demands and establishing education expertise. The findings show that discourses and enactments of transparency can be effective in drawing targeted and repeated attention to select things, such as funding inequities. However, such discourses can also be utilized to obscure other issues, such as persistent disparities in academic achievement by race. When used synonymously with accountability, transparency can, and is, incorrectly positioned as an education solution.
Geschichte und Verantwortung
Authors: Langer Robert
Published: September 2016

Die Stadtbibliothek Bautzen untersucht als erste öffentliche Bibliothek ihre Bestände im Sachgebiet Altbestand/Regionalkunde (ehemalige wissenschaftliche Abteilung) systematisch auf Bücher, die während der Zeit des Nationalsozialismus unrechtmäßig in ihren Besitz gelangten. Dabei erwächst ihr aus der eigenen Institutionsgeschichte eine Verantwortung, die mit dem Fortschreiten des NS-Raubgutprojektes und den ersten Restitutionen deutlich zu Tage tritt.
The standard sign conjecture on algebraic cycles: The case of Shimura varieties
Authors: Morel Sophie , Suh Junecue
Published: September 2016

We show how to deduce the standard sign conjecture (a weakening of the Künneth standard conjecture) for Shimura varieties from some statements
about discrete automorphic representations (Arthur’s conjectures plus a bit more).
We also indicate what is known (to us) about these statements.
Anti-adenovirus activity, antioxidant potential, and phenolic content of black tea (Camellia sinensis Kuntze) extract
Authors: Karimi Ali , Moradi Mohammad-Taghi , Alidadi Somayeh , Hashemi Leila
Published: August 2016

Background

Adenovirus (ADV) causes a number of diseases in human, and to date, no specific antiviral therapy is approved against this virus. Thus, searching for effective anti-ADV agents seems to be an urgent requirement. Many studies have shown that components derived from medicinal plants have antiviral activity. Therefore, the present study was aimed to evaluate in vitro anti-ADV activity and also antioxidant potential and total phenolic compounds of black tea (Camellia sinensis) crude extract.

Methods

In this study, the hydroalchoholic extract of black tea was prepared and its anti-ADV activity was evaluated on HEp2 cell line using MTT [3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide] assay. The 50 % inhibitory concentration (IC50) and 50 % cytotoxicity concentration (CC50) of the extract were determined using regression analysis. Its inhibitory effect on adsorption and/or post-adsorption stages of the virus replication cycle was evaluated. To determine antioxidant activity, total phenol content, and flavonoids content of the extract, the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay, Folin–Ciocalteu method, and aluminum chloride colorimetric method were used, respectively.

Results

The CC50 and the IC50 of the extract were 165.95±12.7 and 6.62±1.4 µg/mL, respectively, with the selectivity index (SI) of 25.06. This extract inhibited ADV replication in post-adsorption stage. The IC50 of DPPH radical was 8±1.41 μg/mL, compared with butylated hydroxytoluene, with IC50 of 25.41±1.89 μg/mL. The total phenol and flavonoid contents of the extract were 341.8±4.41 mg gallic acid equivalent per gram and 21.1±2.11 mg/g, respectively.

Conclusions

Having SI value of 25.06 with inhibitory effect on ADV replication, particularly during the post-adsorption period, black tea extract could be considered as a potential anti-ADV agent. The antiviral activity of this extract could be attributed to its phenolic compounds.
A Systems-Of-Systems Conceptual Model and Live Virtual Constructive Simulation Framework for Improved Nuclear Disaster Emergency Preparedness, Response, and Mitigation
Authors: Davis Matthew , Proctor Michael , Shageer Buder
Published: August 2016

Nuclear disasters have severe and far-reaching consequences. Emergency managers and first responders from utility owners to local, state, and federal civil authorities and the Department of Defense (DoD) must be well prepared in order to rapidly mitigate the disaster and protect the public and environment from spreading damage. Given the high risks, modeling and simulation (M&S) plays a significant role in planning and training for the spectrum of derivate scenarios. Existing reactor models are largely legacy, stove-piped designs lacking interoperability between themselves and other M&S tools for emergency preparedness system evaluation and training. Unmanned systems present a growing area of technology promising significant improvement in response and mitigation. To bridge the gap between current and future models, we propose a conceptual model (CM) for integrating live, virtual, and constructive (LVC) models with nuclear disaster and mitigation models utilizing a system-of-systems (SoS) approach. The CM offers to synergistically enhance current reactor and dispersion simulations with intervening avatar and agent simulations. The SoS approach advances life cycle stages including concept exploration, system design, engineering, training, and mission rehearsal. Component subsystems of the CM are described along with an explanation of input/output requirements. A notional implementation is described. Finally, applications to analysis and training, an evaluation of the CM based on recently proposed criteria found in the literature, and suggestions for future research are discussed.
Application of Taguchi Method for Optimization of Parameters in Turning Operation
Authors: Singaravel B. , Selvaraj T.
Published: August 2016

Cutting tool vibration analysis is the effective way to understand the machining characteristics of any material. In the present work, the effect of process parameters on cutting tool vibration is estimated using Taguchi method in turning of EN25 steel. Taguchi method uses Signal-to-Noise ratio (S/N) and Analysis of Variance (ANOVA) to determine the optimum level of process parameters and significant parameters. The results showed that cutting speed of 215 m/min, feed rate of 0.07 mm/rev and depth of cut of 0.5 mm are the optimum combination of process parameters. Cutting speed and depth of cut are the influencing parameters on cutting tool vibration. The results are experimentally verified and the results based on turning process response can be effectively improved.
Experimental Investigation of Multiple Quality Characteristics of Laser Beam Machined Surface using Integrated Taguchi and Fuzzy Logic Method
Authors: Kumar Anish , Kumar Vinod , Sharma Gaurav
Published: August 2016

In laser cutting, the capability of laser cutting mainly depends on optical and thermal properties of work material. The surface quality and metallurgical properties of the product is most important from the point of laser cutting quality. The present research work explores the modeling and optimization of laser beam cutting process parameters by using hybrid approach of Taguchi based fuzzy logic. The multi-response optimization of process parameters has been done to improve geometrical accuracy by minimizing the kerf width and kerf deviation. The four input parameters power, gas pressure, feed rate, pulse frequency and three output parameters kerf width (KW), kerf deviation (KD) and material removal rate (MRR) have been taken for the experimentation work. The S/N ratios taken for the KW and KD is of the smaller-the-better type and MRR is of the higher the better type. The predicting fuzzy logic model is implemented on Fuzzy Logic Toolbox of MATLAB using Mamdani technique. The fuzzy logic theory has been applied to compute the fuzzy multi-response performance index (FMRPI). This performance index is further used for multi-objective optimization. The selected samples were analyzed using scanning electron microscope. The predicted optimum results have been validated by performing the confirmation tests. The confirmation tests showed the considerable reduction in kerf deviation and increase in material removal rate.
A combined approximation for the traveling tournament problem and the traveling umpire problem
Authors: Bender Marco , Westphal Stephan
Published: August 2016

We consider the traveling tournament problem (TTP) and the traveling umpire problem (TUP). In TTP, the task is to design a double round-robin schedule, where no two teams play against each other in two consecutive rounds, and the total travel distance is minimized. In TUP, the task is to find an assignment of umpires for a given tournament such that every umpire handles at least one game at every team’s home venue and an umpire neither visits a venue nor sees a team (home or away) too often. The task is to minimize the total distance traveled by the umpires. We present a combined approximation for this problem, when the number of umpires is odd. We therefore first design an approximation algorithm for TTP and then show how to define an umpire assignment for this tournament such that a constant-factor approximation for TUP is guaranteed.
Binuclear trivalent and tetravalent uranium halides and cyanides supported by cyclooctatetraene ligands
Authors: Wang Cong-Zhi , Wu Qun-Yan , Lan Jian-Hui , Chai Zhi-Fang , Gibson John K. , Shi Wei-Qun
Published: August 2016

Although the first organoactinide chloride Cp3UCl (Cp=η5-C5H5) was synthesized more than 50 years ago, binuclear uranium halides remain very rare in organoactinide chemistry. Herein, a series of binuclear trivalent and tetravalent uranium halides and cyanides with cyclooctatetraene ligands, (COT)2U2Xn(COT=η8-C8H8; X=F, Cl, CN;n=2, 4), have been systematically studied using scalar-relativistic density functional theory (DFT). The structures with bridging halide or cyanide ligands were predicted to be the most stable complexes of (COT)2U2Xn, and all the complexes show weak antiferromagnetic interactions between the uranium centers. However, for each species, there is no significant uranium-uranium bonding interaction. The bonding between the metal and the ligands shows some degree of covalent character, especially between the metal and terminal halide or cyanide ligands. The U-5f and 6d orbitals are predominantly involved in the metal-ligand bonding. All the (COT)2U2Xnspecies were predicted to be more stable compared to the mononuclear half-sandwich complexes at room temperature in the gas phase such that (COT)2U2X4might be accessible through the known (COT)2U complex. The tetravalent derivatives (COT)2U2X4are more energetically favorable than the trivalent (COT)2U2X2analogs, which may be attributed to the greater number of strong metal-ligand bonds in the former complexes.
Pipeline Power: A Case Study of Strategic Network Investments
Authors: Hubert Franz , Cobanli Onur
Published: August 2016

We analyze the impact of three controversial pipeline projects on the power structure in the Eurasian network for natural gas. Two pipelines, “Nord Stream” and “South Stream,” allow Russian gas to bypass transit countries, Ukraine and Belarus. The third project, “Nabucco,” aims at diversifying Europe’s gas imports by accessing producers in Middle East and Central Asia. If network power is measured with the Shapley Value we obtain a clear ranking of the projects which corresponds to the observed investment patterns. Nord Stream’s strategic value is huge, easily justifying the high investment cost for Germany and Russia. The additional leverage obtained through South Stream is much smaller and Nabucco is not viable. For the nucleolus in contrast, none of the pipelines has any strategic relevance at all, which contradicts the empirical evidence on investment.
Synthesis and characterization of two new chiral Kemp’s acid derivatives: structures fixed by a peculiar system of N–H···O, C–H···O and C–H···N hydrogen bonds
Authors: Pažout Richard , Maixner Jaroslav , Pecháček Jan , Vilhanová Beáta , Kačer Petr
Published: August 2016

New chiral imide-oxazoline derivatives of Kemp’s acid were synthesized with the aim to produce new ligands suitable for catalytic asymmetric reactions. Compound 1 is C18H28N2O3, systematic name (1R, 5S, 7R)-7-[(S)-4-tert-butyl-4,5-dihydrooxazole-2-yl]-1,5,7-trimethyl-3-azabicyclo-[3.3.1]-nonane-2,4-dione. Compound 2 is C21H26N2O3, systematic name (1R,5S,7R)-7-[(S)-4-benzyl-4,5-dihydrooxazole-2-yl]-1,5,7-trimethyl-3-azabicyclo-[3.3.1]-nonane-2,4-dione. Both compounds contain two molecules with very similar conformations in the asymmetric unit. The two structures were characterized by single crystal X-ray diffraction. DFT calculations of two possible distinct conformations were performed to elucidate the differences between the preferred conformation in vacuo and the one observed in the single crystal. Also, charges on the key atoms of the compounds were compared with a common ligand used for asymmetric transfer hydrogenation.
Crystalline chalcogenido metalates – synthetic approaches for materials synthesis and transformation
Authors: Thiele Günther , Santner Silke , Dehnen Stefanie
Published: August 2016

The formation and transformation of crystalline chalcogenido metalates in ionic liquids as solvents is discussed as a new synthetic approach for the generation of novel materials. A comparison to conventional solvothermal reactions, classical high-temperature syntheses and chemical solution based approaches in common is discussed.
Accreting Scalar-Field Models of Dark Energy Onto Morris-Thorne Wormhole
Authors: Chattopadhyay Surajit , Pasqua Antonio , Radinschi Irina
Published: August 2016

The present paper reports a study on accreting tachyon, Dirac-Born-Infeld essence and h-essence scalar field models of dark energy onto Morris-Thorne wormhole. Using three different parameterisation schemes and takingH = H0 + H1t$H\, = \,{H_0}\, + \,{{{H_1}} \over t}$, we have derived the mass of the wormhole for all of the three parameterisation schemes that are able to get hold of both quintessence and phantom behaviour. With suitable choice of parameters, we observed that accreting scalar field dark energy models are increasing the mass of the wormhole in the phantom phase and the mass is decreasing in the quintessence phase. Finally, we have considered accretion with power law form of scale factor and without any parameterisation scheme for the equation of state parameter and observed the fact that phantom-type dark energy supports the existence of wormholes.
Spin Dynamics and Establishing of Internal Quasi-Equilibrium in Dilute Paramagnetic Solids
Authors: Atsarkin Vadim A. , Dzheparov Fridrikh S.
Published: August 2016

A brief review is given of the development and experimental verification of the two-temperature quasi-equilibrium concept as applied to EPR in dilute paramagnetic solids. Existing experimental data on spectral diffusion in a dipolar broadened EPR line and excitation transfer inside the electron dipolar reservoir are newly considered. The discussion is supplemented with theoretical arguments based on the concentration and cluster expansion techniques. Conditions and limitations of applicability of the two-temperature quasi-equilibrium model to electron spin systems with random distribution of paramagnetic centers are cleared up.
Progestin withdrawal at parturition in the mare
Authors: Legacki Erin L , Corbin C J , Ball B A , Wynn M , Loux S , Stanley S D , Conley A J
Published: August 2016

Mammalian pregnancies need progestogenic support and birth requires progestin withdrawal. The absence of progesterone in pregnant mares, and the progestogenic bioactivity of 5α-dihydroprogesterone (DHP), led us to reexamine progestin withdrawal at foaling. Systemic pregnane concentrations (DHP, allopregnanolone, pregnenolone, 5α-pregnane-3β, 20α-diol (3β,20αDHP), 20α-hydroxy-5α-dihydroprogesterone (20αDHP)) and progesterone) were monitored in mares for 10days before foaling (n=7) by liquid chromatography–mass spectrometry. The biopotency of dominant metabolites was assessed using luciferase reporter assays. Stable transfected Chinese hamster ovarian cells expressing the equine progesterone receptor (ePGR) were transfected with an MMTV-luciferase expression plasmid responsive to steroid agonists. Cells were incubated with increasing concentrations (0–100nM) of progesterone, 20αDHP and 3α,20βDHP. The concentrations of circulating pregnanes in periparturient mares were (highest to lowest) 3α,20βDHP and 20αDHP (800–400ng/mL respectively), DHP and allopregnanolone (90 and 30ng/mL respectively), and pregnenolone and progesterone (4–2ng/mL). Concentrations of all measured pregnanes declined on average by 50% from prepartum peaks to the day before foaling. Maximum activation of the ePGR by progesterone occurred at 30nM; 20αDHP and 3α,20βDHP were significantly less biopotent. At prepartum concentrations, both 20αDHP and 3α,20βDHP exhibited significant ePGR activation. Progestogenic support of pregnancy declines from 3 to 5days before foaling. Prepartum peak concentrations indicate that DHP is the major progestin, but other pregnanes like 20αDHP are present in sufficient concentrations to play a physiological role in the absence of DHP. The authors conclude that progestin withdrawal associated with parturition in mares involves cessation of pregnane synthesis by the placenta.
The endocannabinoid anandamide impairs in vitro decidualization of human cells
Authors: Almada M , Amaral C , Diniz-da-Costa M , Correia-da-Silva G , Teixeira N A , Fonseca B M
Published: August 2016

Endocannabinoids (eCBs) are endogenous mediators that along with the cannabinoid receptors (CB1 and CB2), a membrane transporter and metabolic enzymes form the endocannabinoid system (ECS). Several eCBs have been discovered with emphasis on anandamide (AEA). They are involved in several biological processes such as energy balance, immune response and reproduction. Decidualization occurs during the secretory phase of human menstrual cycle, which involves proliferation and differentiation of endometrial stromal cells into decidual cells and is crucial for the establishment and progression of pregnancy. In this study, a telomerase-immortalized human endometrial stromal cell line (St-T1b) and non-differentiated primary cultures of human decidual fibroblasts from term placenta were used to characterize the ECS using immunoblotting and qRT-PCR techniques. It was shown that St-T1b cells express CB1, but not CB2, and that both receptors are expressed in HdF cells. Furthermore, the expression of fatty acid amide hydrolase (FAAH), the main degrading enzyme of AEA, increased during stromal cell differentiation. AEA inhibited cell proliferation, through deregulation of cell cycle progression and induced polyploidy. Moreover, through CB1 binding receptor, AEA also impaired cell differentiation. Therefore, AEA is proposed as a modulator of human decidualization. Our findings may provide wider implications, as deregulated levels of AEA, due toCannabis sativaconsumption or altered expression of the metabolic enzymes, may negatively regulate human endometrial stromal cell decidualization with an impact on human (in)fertility.

Free Portuguese abstract: A Portuguese translation of this abstract is freely available athttp://www.reproduction-online.org/content/152/4/351/suppl/DC1.
Caracterización y determinación de ecotipos de oca(oxalis tuberosa), para el procesamiento de harinas en la Quebrada de Ancash, distrito y provincia de Yungay, Región Ancash.
Authors: Yenque Dedios Julio , Santos De La Cruz Eulogio , Salas Bacalla Julio , Feliciano Muñoz Osiris , Lavado Soto Aurelio
Published: August 2016

El Perú tiene innumerables recursos naturales alimenticios de origen andino, uno de los cuales es la oca, la que aun no se ha aprovechado y masificado su consumo; razón por el que este estudio plantea hacer un análisis de los tipos de oca que existen en la sierra de la región Ancash, determinando sus características físicas y químicas para su posterior recomendación, dentro de un contexto de una posibilidad de industrialización. Para cumplir este cometido, han confluido esfuerzos profesionales y de campo. En este sentido ha sido posible la participación de la Universidad a través de sus laboratorios y Centros de Procesamiento, investigadores docentes e independientes y productores de oca, y con la finalidad de realizar ensayos de laboratorio para la obtención de harina y néctar.
Contaminación sonora por ruido vehicular en la Avenida Javier Pardo
Authors: Santos De La Cruz Eulogio
Published: August 2016

La contaminación sonora producida por el ruido de los vehículos es el factor que más molestias causa a la población urbana, los habitantes de Lima están expuestos a este problema, esto implica conocer la problemática del ruido y que demanda un ingente esfuerzo, resultando difícil abarcar toda la ciudad, por ello se opta por zonas, eligiendo la avenida Javier Prado, entre la intersección con la avenida Aviación por el este y la avenida Aviación por el Este y la avenida Brasil por el Oeste, haciendo encuestas a los transeúntes y conductores en la hora pico 07:00-09:00 y 15:00-19:00 horas en el área de más densa congestión vehicular, para mitigar se requiere una buena planificación urbana, diseño medioambiental óptimo de las vías y con el adecuado uso del suelo se lograría un mínimo,o impacto del ruido.
Diseño e implementación de un prototipo automatizado para el procesamiento de pastas y líquidos.
Authors: Ruiz Lizama Edgar , Inche Mitma Jorge , Chung Pinzás Alfonso , Tello Yuen Roberto
Published: August 2016

El artículo trata el siguiente problema: ¿Qué instrumentos físicos y virtuales interactuan en una Interface3 Hobre Ma´quina a fin automatizar un prototipo para el Procesamiento de Pastas y Liquídos?; El diseño incluye el dimensionado y la selección de dispositivos. La implementación considera la plataforma SYSTEM 302 para la supervisión y control de procesos; se obtuvo como resultado tangible un módulo automatizado cuya inversión fue devuelta mediante los cursos del CEMA.
Mejoras en el proceso productivo y modernización mediante sustitución y tecnologías limpias en un molino de arroz
Authors: Najar A. Carlos , Alvarez Merino José
Published: August 2016

La producción de arroz, que comprende la agricultura, procesos productivos y distribución, requiere de análisis a fin de mejorar su eficiencia y competitividad. En este contexto, en el presente trabajo, se propone mejoras que redunden en la producción y productividad en un molino de arroz ubicado en la región Arequipa. Para tal fin se realiza un diagnóstico del proceso productivo, un benchmarking con las empresas del sector, así como se introducen conceptos de producción más limpia.
Diseño de una estación virtual para el control de las perturbaciones que afectan la temperatura de los procesos industriales
Authors: Poma Deza Jorge , Tello Yuen Roberto , Ruiz Lizama Edgar
Published: August 2016

El artículo presenta el desarrollo de una estación virtual usando LabVIEW, software de instrumentación virtual fabricado por National Instruments, que permite monitorear y supervisar variables en el tiempo real en un proceso industrial. Dicho software proporciona una interfaz gráfica de control virtual, toma en cuenta el calor requerido para el proceso en funcionamiento, sin embargo, las interferencias generadas en el proceso logran un incremento de la temperatura del sistema, incorporando una alarma para evitar pérdidas en la producción. Finalmente, se han diseñado opciones de muestreo en el panel de control, como cantidad de datos a medir, tiempo transcurrido, velocidad de muestro, cantidad de datos tomados, indicar el tiempo en que ha ocurrido algún evento, etc. importantes para facilitar la toma de decisiones.
Los indicadores financieros y el Valor Económico Agregado(EVA) en la creación de valor
Authors: Vergiú Canto Jorge , Bendezú Mejía Christian
Published: August 2016

La meta de cualquier empresa es buscar elevar el valor de la empresa a través de maximizar las utilidades para los accionistas, equilibrar el pasivo y el patrimonio a fin minimizar los niveles de riesgo y tener una liquidez adecuada para afrontar los compromisos del corto plazo Es en esta búsqueda que se comienza el verdadero reto de hallar el valor de la empresa e interpretarla, para lo cual se tiene dos planteamientos: el tradicional a través de los Indicadores Financieros que si bien son razones claras y fáciles de calcular, reducen su efectividad como instrumentos de medición de riqueza y el Valor Económico Agregado(EVA) el cual es una herramienta que trata de contrarrestar las limitaciones de estos indicadores al valorizar y evaluar el desempeño de la gestión a través de la creación de valor.
EDITORIAL
Authors: Rojas Lazo Oswaldo , Ruiz Lizama Edgar
Published: August 2016

Ciencia, Tecnología e Innovación para el desarrollo nacional
¿A una empresa le conviene endeudarse con el banco?
Authors: Santos Jiménez Néstor
Published: August 2016

Las empresa cuentan con múltiples alternativas de financiamiento que requieren ser analizadas para definir la combinación adecuada entre deuda y el aporte de capital del accionista(o accionistas). El modelo financiero basado en el VPN como criterio de decisión ayuda a seleccionar la mejor alternativa de financiamiento con deuda. La deuda bancaria mejora el valor de la empresa, pero se requiere un equilibrio entre endeudamiento y capital propio. La deuda bancaria es conveniente en la medida que la tasa de interés sea inferior al costo de oportunidad del accionista . El beneficio de la deuda para el accionista se da cuando la empresa contabiliza los gastos financieros en la determinación de la participación de los trabajadores en las utilidades de la empresa y en el pago del impuesto a la renta a la SUNAT.
Análisis de riesgo en la evaluación de alternativas de inversión utilizando Crystal Ball®
Authors: Del Carpio Gallegos Javier , Eyzaguirre Tejada Roberto
Published: August 2016

El presente artículo muestra cómo el uso del software Crystal Ball®, incorporando en una hoja de cálculo, puede ayudar a tomar mejores decisiones de inversión aplicando la técnica de simulación Monte Cario.
Desarrollo de un modelo Multifactorial y dinámico para la medición de los intangibles de empresas de manufactura
Authors: García Zapata Teonila , Vergiu Canto Jorge , Párraga Velásquez Rosario , Santos Jimenéz Néstor
Published: August 2016

La presente investigación trata sobre el desarrollo de un modelo multifactorial y dinámico(MFD) para la medición de los intangibles aplicados a empresas de manufactura localizadas en el Perú. El modelo desarrollo permitirá probar que el conocimiento es un diferencial de competitividad tradicional no está habilitada para medir estos aspectos hoy en día. En este trabajo se analiza una de las empresas de manufactura peruana para saber hasta que punto la información sobre sus indicadores que manejan sirven para identificar el intangible(capital intelectual) con la finalidad que en algún momento se pueda estandarizar un modelo propio para la medición de los intangibles de las empresas de manufactura del Perú.
Evaluación y análisis de la calidad de un servicio de apoyo desde la perspectiva del usuario: Primer paso hacia la confiablidad
Authors: Pérez Rave Jorge , Parra Mesa Carlos
Published: August 2016

Este artículo exhibe la evaluación y el análisis de la calidad del servicio de soporte técnico de la Facultad de Ingeniería de la Universidad de Antioquia(Colombia). La metodología integra elementos de: investigación cualitativa, estadística multivariable, calidad, teoría de probabilidad y confiabilidad de sistemas. En el presente artículo se discute que, el análisis de la calidad debe verse como un primer paso hacia el análisis de la confiabilidad, el cual constituye una práctica aún mas efectiva para las organizaciones, por permitir conocer el comportamiento que caracteriza a la calidad a lo largo del tiempo, las fallas del servicio, la severidad de las mismas, e identificar con mayor certeza hacia donde deben orientarse los esfuerzos de mejoramiento.
Programación genérica en C++, usando Metaprogramación
Authors: Raffo Lecca Eduardo
Published: August 2016

La complejidad de nuestros programas, va en aumento con los problemas a los que nos enfrentamos. Una forma de darle solución, es repetir una y otra vez las mismas estructuras, tal como nos acostumbró la programación tradicional o imperativa. este artículo, explora las relaciones entre plantillas C++, la programación genérica y la habilidad de desarrollar computaciones estáticas y generación de código. Muchos desarrolladores aplicaciones en computación científica; y el mecanismo de las plantillas en C++ les permite resolver importantes problemas en el diseño de librerías de clase.
Reconocimiento automático invariante de sujetadores metálicos e squineros, basado en la transformada de Hough.
Authors: Montenegro Joo Javier
Published: August 2016

La Transformada polar de Hough ha sido usada para crear un sistema para reconocimiento invariante automático de objetos poligonales, el cual opera independientemente de la posición, orientación y tamaño de los objetos y, ha sido exitosamente aplicado al reconocimiento de sujetadores metálicos esquineros(forma de L). Como el sistema es autónomo, podría ser aplicado a la automatización del control de calidad y de la clasificación, en la industria.
Una metodología para sectorizar pacientes en el consumo de medicamentos aplicando Datamart y Datamining en un hospital
Authors: Tapia Rivas Ivan , Ruiz Rivera María , Ruiz Lizama Edgar
Published: August 2016

El presente trabajo, propone un método para el análisis de datos en la forma con que se consumen los medicamentos en un hospital peruano a fin de poder identificar algunas realidades o características no observables que producirán desabastecimiento o insatisfacción del paciente, el cual servirá como una herramienta para la toma de decisión sobre el abastecimiento de medicamentos en el hospital. Aquí se complementan técnicas de datamart, de extracción y carga de datos, asín como algoritmos de minería de datos como K-means para sectorizar los consumos de medicamentos mencionados. finalmente se muestran gráficas con algunos resultados extraídos de las pruebas.
EDITORIAL
Authors: Yenque Dedios Julio| , Rojas Lazo Oswaldo , Ruiz Lizama Edgar
Published: August 2016

Ciencia, Tecnología e Innovación para el desarrollo nacional
Evaluación del exponente de la función de corrección de la velocidad de sedimentación de Richardson y Zaki para micro partículas
Authors: Salinas Salas Gonzalo , Babick Frank
Published: August 2016

La función de corrección formulada por Richardson y Zaki en 1954, se utiliza para determinar la velocidad de sedimentación de un colectivo de partículas a partir de la velocidad de una partícula que no se encuentra sujeta a la acción de las fuerzas de otras partículas en la suspensión. Dado el tamaño de las partículas que es micrométrico y el valor del número de Reynolds del escurriento que es menor a 0,25; se emplea la solución de Stokes para evaluar la velocidad de éstas, por lo que el valor del exponente de la función de corrección de Richardson y Zaki es n = 4,65; independientemente del tamaño. El presente trabajo demuestra a partir de un trabajo experimental con micro partículas que el valor del exponente de la función de corrección de Richardson y Zaki depende de su tamaño y es mayor mientras menor es el diametro de éstas.
Automatic classification of products in the industry via invariant boundary moments
Authors: Montenegro Joo Javier
Published: August 2016

La técnica de los Momentos Invariantes de Borde (MIB) es aplicada a la clasificación automática de dos diferentes objetos seleccionados al azar, independientemente de sus dimensiones, posición y orientación. Se muestra que si los objetos difieren solo en posición y orientación (sus dimensiones se mantienen), el poder de los MIB es optimo; sin embargo, cuando se incluyen variaciones en las dimensiones, los valores de los MIBs se superponen, lo cual limita su uso como una herramienta de clasificación, en casos como estos, debe introducirse un margen de tolerancia predefinido.
Aplicación del costeo basado en actividades en las Universidades
Authors: Del Carpio Gallegos Julio
Published: August 2016

El presente artículo muestra cómo el costeo basado en actividades puede ser aplicado en la docencia universitaria, y cómo esta herramienta de gestión puede ayudar a una mejor administración de recursos.
Compromiso organizacional de los trabajadores de una Universidad Pública
Authors: Loli Pineda Alejandro
Published: August 2016

Este artículo es un trabajo realizado en una muestra de 72 sujetos, con el objeto de conocer el compromiso de los trabajadores para con la organización donde laboran y la relación entre el compromiso organizacional y las variables demográficas. Los resultados muestran que la mayoría de ellos tienen un compromiso normal con su organización y que no existe relación con las variables demográficas analizadas. Un análisis cruzado entre los factores del compromiso organizacional arroja que existe relación significativa entre algunos de ellos.
Algoritmos de integración numérica
Authors: Raffo Lecca| Eduardo , Mayta Huatuco Rosmeri , Perez Quispe Victor
Published: August 2016

En este artículo se desarrollan e implementan, los algoritmos de integración numérica, que permiten solucionar problemas de ciencias e ingeniería; tales como el cálculo de áreas, volúmenes, mecánica aplicada, y ecuaciones diferenciales (sistemas dinámicos). Dada la necesidad de contar con resultados de gran precisión, se analiza las diferentes reglas de integración numérica; basadas en los errores que ocurren cuando el integrando es reemplazado por un polinomio de interpolación P(x), conocida como las fórmulas de integración de Newton-Cotes. La regla de la extrapolación de Richardson, puede ser aplicada a cualquier fórmula de cuadratura de Newton-Cotes; o cualquier computación que se encuentra basada en una rejilla de ancho h y un error descrito como una potencia de h.