bluuebunny/crossref_metadata_2025 huggingface dataset:
Clinical and psychopathological aspects of catatonia pathomorphosis
Authors: Neznanov N. G. , Kuznetsov A. V.
Published: April 2020

Over the last century frequency of diagnosed catatonic states continuously decreased. This phenomenon can be explained through hypothesis of pathomorphosis of psychiatric diseases. Pathomorphosis is an important aspect of mental diseases, including catatonic states, especially therapeutic pathomorphosis. Changes in clinical presentation of psychosis led to under-recognition of catatonic signs, that cause incorrect diagnostic and treatment tactics. The aim of this study is to investigate clinical and psychopathological features of psychosis with catatonic features and actual differences in clinical presentation compared to traditional descriptions and earlier clinical cases. Two groups of patients was explored. First is patients, which admitted to psychiatric hospital due to psychosis with catatonic features. Second group contains archival clinical cases of patients, which were treated since 1969 to 1972, before introduction of atypical antipsychotics to clinical practice.
EFEITOS DA MOBILIZAÇÃO PRECOCE EM CRIANÇAS COM PNEUMONIA ASSOCIADA A VENTILAÇÃO MECÂNICA: EFEITOS SOBRE VARIÁVEIS NÃO LINEARES DA VARIABILIDADE DA FREQUÊNCIA CARDÍACA
Authors: Da Rocha Gabriela Quaresma , Dos Santos Juliana Bezerra , De Oliveira Márcio Helder Lima , Avila Paulo Eduardo Santos , Rocha Rodrigo Santiago Barbosa
Published: April 2020

A pesquisa teve como objetivo verificar os efeitos da mobilização precoce em crianças com pneumonia associada à ventilação mecânica (PAV) sobre variáveis não lineares da variabilidade da frequência cardíaca. Foi realizado um ensaio clínico, prospectivo, de caráter quantitativo realizado em 13 pacientes de ambos os gêneros, com idade média de 3±2,3 anos, com diagnóstico de PAV. O estudo foi aprovado pelo Comitê de Ética e Pesquisa da FSCMP, parecer 2.084.580 e registo no Clinical Trials NCT03343717. A análise da recorrência, assim como a DFA ?1, não obtiveram resultados relevantes para o estudo, com p=0,812 e p=0,09, respectivamente. A variável determinismo apresentou resultado com nível de significância
ANÁLISE ELETROMIOGRÁFICA DOS MÚSCULOS TIBIAL ANTERIOR E SÓLEO EM PACIENTES HEMIPARÉTICOS NOS AMBIENTES AQUÁTICO E TERRESTRE
Authors: Bueno de Araujo Luize , Braga Douglas Martins , Kanashiro Mirna Sayuri , Baccaro Valmir Marcos , De Souza Cristiane Dias A. , Batista Bruna Paulenas , Lourenço Mariana Armando
Published: April 2020

O objetivo deste trabalho foi verificar a ativação dos músculos tibial anterior e sóleo em pacientes hemiparéticos e indivíduos hígidos, em bipedestação no ambiente aquático em comparação ao solo e verificar se há correlação entre ativação muscular e medidas funcionais. Trata-se de um estudo transversal. Foram incluídos 6 indivíduos hígidos (grupo controle – GC) e 6 hemiparéticos (grupo estudo – GE). Os participantes foram caracterizados por meio dos instrumentos Mini-Exame do Estado Mental (MEEM), Escala de Equilíbrio de Berg (EEB) e Medida da Independência Funcional (MIF), eletromiografia (EMG) de superfície dos músculos tibial anterior e sóleo em posturas em bipedestação, nos ambientes terrestre e aquático em dois níveis de imersão. O GE obteve pontuação média de 24±6,7 no MEEM, 80,8±2,7 na MIF, 48,5±7,1 na EEB. A EMG evidenciou maior ativação do músculo sóleo no GE quando comparado ao GC, bem como maior ativação no lado hemiparético quando comparado ao lado não afetado. Constata-se correlação inversamente proporcional entre a EMG e a EEB no GE. Com esse estudo foi possível compreender o comportamento dos músculos tibial anterior e sóleo de hemiparéticos no ambiente aquático quando comparado ao solo, em posturas comumente utilizadas na reabilitação aquática. Esse melhor entendimento pode possibilitar uma intervenção mais adequada.
RISCO DE USO DE DROGAS EM ADOLESCENTES: IMPORTÂNCIA DO PROGRAMA SEGUNDO TEMPO
Authors: Da Silva Monica Jane Cabral , Leite Tarciano Ricardo Holanda , Oliveira Leonardo Dos Santos , Da Silva Priscilla Pinto Costa , Rodrigues Emília Amélia Pinto Costa , Brito Aline De Freitas
Published: April 2020

O Programa Segundo Tempo (PST) é um programa do Governo Federal que busca democratizar o acesso à prática do esporte, por meio da parceria com as Secretarias de Esporte e Lazer. Entende-se que por meio da prática esportiva, os sujeitos têm a possibilidade de compreender melhor seu corpo, suas limitações e potencialidades, entre outros aspectos. Além disso, o esporte pode conduzir as crianças e adolescentes para um caminho longe das drogas. Nesta perspectiva, este estudo identificou o risco para o uso de drogas ilícitas nos alunos praticantes do PST da cidade de João Pessoa/PB por meio do perfil socioeconômico e de caráter familiar. Sessenta e dois adolescentes, com idade entre 12 e 16 anos, matriculados no PST, responderam a um questionário sobre informações pessoais, socioeconômicas e culturais, além de perguntas objetivas relacionadas ao tema do estudo. Foi verificado um maior percentual do uso de drogas ilícitas entre os adolescentes com pais divorciados (56,5%). Observou-se uma associação entre o uso de drogas com o tempo livre, com o parente que reside com o adolescente e com o estado civil dos pais. Em adição, ficou caracterizada uma tendência linear de associação entre o o uso de drogas e a renda familiar dos alunos/escolaridade da mãe. Foi possível constatar que a prática de esportes é a atividade que ocupa o maior tempo livre destes adolescentes. Neste caso, é preciso ater-se à importância do diálogo dentro dos projetos sociais, podendo ser um meio eficaz aliada a prática esportiva. Portanto, é necessário um trabalho multidisciplinar com professores de educação física, assistentes sociais e psicólogos, para que, de forma conjunta, elaborem estratégias de intervenção com intuito de proporcionar uma melhor qualidade de vida a esses adolescentes.
OS ESPORTES COLETIVOS NA ESCOLA: REFLEXÕES SOBRE AS ATIVIDADES CURRICULARES DESPORTIVAS
Authors: Andreani Fabiana , De Moraes Adriano Gomes , Cavalieri Beatriz Carvalho , Ferreira Lílian Aparecida
Published: April 2020

Na educação escolar pública do estado de São Paulo, além do momento de aprendizagem do esporte nas aulas de Educação Física, os alunos também têm a possibilidade de participar de atividades esportivas no contraturno, nas chamadas turmas de Atividades Curriculares Desportivas (ACDs) que possuem três categorias de modalidades: esportes (individuais e coletivos), lutas e ginásticas. As ACDs vêm sendo realizadas desde 2001 nas escolas estaduais de São Paulo, contudo, ainda carecem de estudos que nos ajudem a compreender tanto sua caracterização quanto seu processo de desenvolvimento no ambiente escolar. Neste sentido, os objetivos do presente artigo foram identificar e analisar as ACDS de esportes coletivos desenvolvidas nas escolas pertencentes a uma diretoria de ensino no interior de São Paulo. A pesquisa, de abordagem qualitativa, envolveu análise documental e investigação de campo. Foram realizadas entrevistas semiestruturadas com 17 professores e aplicado questionário a 292 alunos, todos estes envolvidos nas turmas de ACDs. Os resultados, após intensa leitura e relações com a literatura correspondente, foram organizados em três categorias de análise, a saber: Circunscrevendo as ACDs (modalidades, gênero e faixa etária); Metodologias de ensino; Expectativas em relação às ACDs. Os dados evidenciados nas três categorias explicitam que o futsal é a modalidade mais presente nas escolas, as turmas masculinas são mais frequentes, as metodologias de ensino baseiam-se majoritariamente em práticas tradicionais de ensino, as expectativas dos docentes relacionam-se mais com os resultados nos jogos escolares enquanto a dos alunos se assenta no gosto pelo esporte que praticam. Nesse sentido, evidenciamos a necessidade de programas de formação continuada que possam desconstruir a visão esportiva seletiva e excludente dos docentes, circunscrita pelo esporte de alto-rendimento. Se quisermos defender uma escola democrática e inclusiva tal visão do esporte precisa ser modificada.
COMPARAÇÃO DA QUALIDADE DE VIDA ENTRE ATLETAS E PARATLETAS BRASILEIROS DE ALTO RENDIMENTO
Authors: Freire Gabriel Lucas Morais , Freire Torres Vanthauze Marques , Vicentini de Oliveira Daniel , Andrade do Nascimento Junior Jose Roberto
Published: April 2020

O objetivo do presente estudo foi comparar a percepção da qualidade de vida (QV) de atletas e paratletas das modalidades de atletismo e natação. Tratou-se de um estudo descritivo e de corte transversal com 127 atletas com média de idade de 20,6 (±3,1) anos, que treinavam em instituições esportivas de Recife-PE e que frequentando regularmente os treinamentos e competições há mais de 2 (dois) anos. Para avaliação da QV foi utilizado o questionário de avaliação abreviado da qualidade de vida da organização mundial de saúde (WHOQOL-BREF) e um questionário sociodemográfico afim de caracterizar a amostra. Para análise dos dados, foi utilizada o teste de normalidade de Kolmogorov-Smirnov. Foi utilizado o teste “U” de Mann-Whitney para a comparação qualidade de vida em função dos grupos (modalidade, sexo e patrocínio). Foi adotada a significância de p < 0,05. Observou-se nos resultados uma menor percepção da Qualidade de Vida no domínio físico e de Qualidade de Vida geral entre os grupos de atletas e paratletas. Não houve diferença significativa quando comparamos os gêneros entre os grupos pesquisados. Foram constatadas diferenças significativas na percepção da Qualidade de Vida entre os atletas com e sem patrocínio, atletas e para-atletas nos domínios físico, psicológico e de Qualidade de Vida geral. Conclui-se que o estudo não revela evidências causais sobre o impacto da Qualidade de Vida em atletas e paratletas, entretanto o mesmo indica boas contribuições para uma maior preocupação das entidades esportivas com melhores condições de transporte, moradia, segurança e recursos financeiros aos atletas e paratletas.
Robot-assisted stereoelectroencephalography exploration of the limbic thalamus in human focal epilepsy: implantation technique and complications in the first 24 patients
Authors: Chaitanya Ganne , Romeo Andrew K. , Ilyas Adeel , Irannejad Auriana , Toth Emilia , Elsayed Galal , Bentley J. Nicole , Riley Kristen O. , Pati Sandipan
Published: April 2020

OBJECTIVE

Despite numerous imaging studies highlighting the importance of the thalamus in a patient’s surgical prognosis, human electrophysiological studies involving the limbic thalamic nuclei are limited. The objective of this study was to evaluate the safety and accuracy of robot-assisted stereotactic electrode placement in the limbic thalamic nuclei of patients with suspected temporal lobe epilepsy (TLE).

METHODS

After providing informed consent, 24 adults with drug-resistant, suspected TLE undergoing evaluation with stereoelectroencephalography (SEEG) were enrolled in the prospective study. The trajectory of one electrode planned for clinical sampling of the operculoinsular cortex was modified to extend it to the thalamus, thereby preventing the need for additional electrode placement for research. The anterior nucleus of the thalamus (ANT) (n = 13) and the medial group of thalamic nuclei (MED) (n = 11), including the mediodorsal and centromedian nuclei, were targeted. The postimplantation CT scan was coregistered to the preoperative MR image, and Morel’s thalamic atlas was used to confirm the accuracy of implantation.

RESULTS

Ten (77%) of 13 patients in the ANT group and 10 (91%) of 11 patients in the MED group had electrodes accurately placed in the thalamic nuclei. None of the patients had a thalamic hemorrhage. However, trace asymptomatic hemorrhages at the cortical-level entry site were noted in 20.8% of patients, who did not require additional surgical intervention. SEEG data from all the patients were interpretable and analyzable. The trajectories for the ANT implant differed slightly from those of the MED group at the entry point—i.e., the precentral gyrus in the former and the postcentral gyrus in the latter.

CONCLUSIONS

Using judiciously planned robot-assisted SEEG, the authors demonstrate the safety of electrophysiological sampling from various thalamic nuclei for research recordings, presenting a technique that avoids implanting additional depth electrodes or compromising clinical care. With these results, we propose that if patients are fully informed of the risks involved, there are potential benefits of gaining mechanistic insights to seizure genesis, which may help to develop neuromodulation therapies.
Safety of the paramedian supracerebellar–transtentorial approach for selective amygdalohippocampectomy
Authors: Serra Carlo , Akeret Kevin , Staartjes Victor E. , Ramantani Georgia , Grunwald Thomas , Jokeit Hennric , Bauer Julia , Krayenbühl Niklaus
Published: April 2020

OBJECTIVE

The goal of this study was to assess the reproducibility and safety of the recently introduced paramedian supracerebellar–transtentorial (PST) approach for selective amygdalohippocampectomy (SA).

METHODS

The authors performed a retrospective analysis of prospectively collected data originating from their surgical register of patients undergoing SA via a PST approach for lesional medial temporal lobe epilepsy. All patients received thorough pre- and postoperative clinical (neurological, neuropsychological, psychiatric) and instrumental (ictal and long-term EEG, invasive EEG if needed, MRI) workup. Surgery-induced complications were assessed at discharge and at every follow-up thereafter and were classified according to Clavien-Dindo grade (CDG). Epilepsy outcome was defined according to Engel classification. Data were reported according to common descriptive statistical methods.

RESULTS

Between May 2015 and May 2018, 17 patients underwent SA via a PST approach at the authors’ institution (hippocampal sclerosis in 13 cases, WHO grade II glioma in 2 cases, and reactive gliosis in 2 cases). The median postoperative follow-up was 7 months (mean 9 months, range 3–19 months). There was no surgery-related mortality and no complication (CDG ≥ 2) in the whole series. Transitory CDG 1 surgical complications occurred in 4 patients and had resolved in all of them by the first postoperative follow-up. One patient showed a deterioration of neuropsychological performance with new slight mnestic deficits. No patient experienced a clinically relevant postoperative visual field defect. No morbidity due to semisitting position was recorded. At last follow-up 13/17 (76.4%) patients were in Engel class I (9/17 [52.9%] were in class IA).

CONCLUSIONS

The PST approach is a reproducible and safe surgical route for SA. The achievable complication rate is in line with the best results in the literature. Visual function outcome particularly benefits from this highly selective, neocortex-sparing approach. A larger patient sample and longer follow-up will show in the future if the seizure control rate and neuropsychological outcome also compare better than those achieved with current common surgical techniques.
Real-time ultrasonography–magnetic resonance image fusion navigation for percutaneous transforaminal endoscopic discectomy
Authors: Xie Peigen , Feng Feng , Cao Junyan , Chen Zihao , He Bingjun , Kang Zhuang , He Lei , Wu Wenbin , Tan Lei , Li Kai , Zheng Rongqin , Rong Limin
Published: April 2020

OBJECTIVE

Percutaneous transforaminal endoscopic discectomy (PTED) is usually performed under fluoroscopic guidance and is associated with a large radiation dose. Ultrasonography (US)–MR image fusion navigation combines the advantages of US and MRI and requires significantly less radiation than fluoroscopy. The purpose of this study was to evaluate the safety and effectiveness of US-MR image fusion navigation for PTED.

METHODS

From January to September 2018, patients with L4–5 lumbar disc herniation requiring PTED were randomized to have the procedure conducted with US-MR image fusion navigation or fluoroscopy. The number of fluoroscopies, radiation dose, duration of imaging guidance, intraoperative visual analog scale (VAS) pain score, intraoperative complications, and clinical outcomes were compared between the groups.

RESULTS

There were 10 patients in the US-MR navigation group and 10 in the fluoroscopy group, and there were no significant differences in age, sex ratio, or BMI between the 2 groups (all p > 0.05). Intraoperatively, the total radiation dose, number of fluoroscopies performed, duration of image guidance, and VAS low-back and leg pain scores were all significantly lower in the US-MRI navigation group than in the fluoroscopy group (all p < 0.05). There were no intraoperative complications in either group. Postoperative improvements in Japanese Orthopaedic Association, Oswestry Disability Index, and VAS pain scale scores were similar between the 2 groups.

CONCLUSIONS

US-MR image fusion navigation is a promising technology for performing PTED and requires significantly less radiation than fluoroscopy.

Clinical trial registration no.: NCT03403244 (ClinicalTrials.gov).
Quantifying the impact of surgical decompression on quality of life and identification of factors associated with outcomes in patients with symptomatic metastatic spinal cord compression
Authors: Lak Asad M. , Rahimi Amina , Abunimer Abdullah M. , Tafel Ian , Devi Sharmila , Premkumar Akash , Ida Fidelia , Lu Yi , Chi John H. , Tanguturi Shyam , Groff Michael W. , Zaidi Hasan A.
Published: April 2020

OBJECTIVE

Metastatic spinal cord compression (MSCC) imposes significant impairment on patient quality of life and often requires immediate surgical intervention. In this study the authors sought to estimate the impact of surgical intervention on patient quality of life in the form of mean quality-adjusted life years (QALY) gained and identify factors associated with positive outcomes.

METHODS

The authors performed a retrospective chart review and collected data for patients who had neurological symptoms resulting from radiologically and histologically confirmed MSCC and were treated with surgical decompression during the last 12 years.

RESULTS

A total of 151 patients were included in this study (mean age 60.4 years, 57.6% males). The 5 most common metastatic tumor types were lung, multiple myeloma, renal, breast, and prostate cancer. The majority of patients had radioresistant tumors (82.7%) and had an active primary site at presentation (67.5%). The median time from tumor diagnosis to cord compression was 12 months and the median time from identification of cord compression to death was 4 months. Preoperative presenting symptoms included motor weakness (70.8%), pain (70.1%), sensory disturbances (47.6%), and bowel or bladder disturbance (31.1%). The median estimated blood loss was 500 mL and the average length of hospital stay was 10.3 days. About 18% of patients had postoperative complications and the mean follow-up was 7 months. The mean pre- and postoperative ECOG (Eastern Cooperative Oncology Group) performance status grades were 3.2 and 2.4, respectively. At follow-up, 58.3% of patients had improved status, 31.5% had no improvement, and 10.0% had worsening of functional status. The mean QALY gained per year in the entire cohort was 0.55. The mean QALY gained in the first 6 months was 0.1 and in the first year was 0.4. For patients who lived 1–2, 2–3, 3–4, or 4–5 years, the mean QALY gained were 0.8, 1.4, 1.7, and 2.3, respectively. Preoperative motor weakness, bowel dysfunction, bladder dysfunction, and ASA (American Society of Anesthesiologists) class were identified as independent predictors inversely associated with good outcome.

CONCLUSIONS

The mean QALY gained from surgical decompression in the first 6 months and first year equals 1.2 months and 5 months of life in perfect health, respectively. These findings suggest that surgery might also be beneficial to patients with life expectancy < 6 months.
Theoretical development of servant leadership in a military context: A mixed methods research
Authors: Bahmani Ebrahim , Teimouri Hadi , Moshref Javadi Mohammad Hosein , Rabbani Khorasegani Ali
Published: April 2020

Purpose: The present study aimed to both develop and validate a model for servant leadership in a military context. Design/methodology/approach: The exploratory sequential mixed methods design with two phases was used. Firstly, in the qualitative phase, the process of servant leadership in a military context was developed using a systematic approach of grounded theory. Secondly, in the quantitative phase, the relationship between the components of servant leadership was explained and the developed model was validated. Findings: The result of the qualitative phase show certain personal, organizational and social antecedents form the ideology of sacrifice in leaders which include: spiritually, intelligent and developed personality (personal antecedents); organizational culture, models and incentives (organizational antecedents); and reference groups and social events (social antecedents). The ideology of sacrifice resulted in choosing special behaviors of servant leadership by leaders. These behaviors include: creating service climate; developing standards; building trust; empowering followers comprehensively; and effective persuasion which cause positive personal and organizational outcomes. According to the results of quantitative phase, the proposed model has an appropriate fitness. Practical implications: The results of this research can be used to develop certain criteria for selecting servant leaders. Accordingly, certain training programs can be developed to promote competencies in organizational leaders. Originality/value: To the best of our knowledge, this is the first study to develop a model for servant leadership in a military context using a mixed methods design.
Amyloid-β in Alzheimer’s Disease: A Study of Citation Practices of the Amyloid Cascade Hypothesis Between 1992 and 2019
Authors: Daly Timothy , Houot Marion , Barberousse Anouk , Agid Yves , Epelbaum Stéphane
Published: April 2020

The amyloid cascade hypothesis (ACH) has dominated contemporary biomedical research into Alzheimer’s disease (AD) since the 1990 s but still lacks definitive confirmation by successful clinical trials of anti-amyloid medicines in human AD. In this uncertain period regarding the centrality of amyloid-β (Aβ) in AD pathophysiology, and with the community apparently divided about the ACH’s validity, we used citation practices as a proxy for measuring how researchers have invested their belief in the hypothesis between 1992 and 2019. We sampled 445 articles citing Hardy & Higgins (1992, “HH92”) and classified the polarity of their HH92 citation according to Greenberg (2009)’s citation taxonomy of positive, neutral, and negative citations, and then tested four hypotheses. We identified two major attitudes towards HH92: a majority (62%) of neutral attitudes with consistent properties across the time period, and a positive attitude (35%), tending to cite HH92 earlier on within the bibliography as time went by, tending to take HH92 as an established authority. Despite the majority of neutral HH92 citations, there was a positive majority of attitudes toward different versions of the ACH and anti-amyloid therapeutic strategies (65%), suggesting that the ACH has been dominant and has undergone significant refinement since 1992. Finally, of those 110 original articles within the sample also testing the ACH empirically, an overwhelming majority (89%) returned a pro-ACH test result, suggesting that the ACH’s central claim is reproducible. Further studies will quantify the extent to which results from different methods within such original studies convergence to provide a robust conclusion vis-à-vis Aβ’s pathogenicity in AD.
Copper Modulation and Memory Impairment due to Hippocampal Tau Pathology
Authors: Harris Christopher J. , Gray Nora E. , Caruso Maya , Hunter Marguex , Ralle Martina , Quinn Joseph F.
Published: April 2020

Background: Environmental copper has been implicated in the pathogenesis of Alzheimer’s disease based on evidence that: 1) brain copper levels increase with age, 2) copper promotes misfolding and toxicity of amyloid-β in vitro, 3) copper-modulating interventions reduce amyloid pathology in animal models. However, the effect of copper upon non-amyloid Alzheimer’s pathology is relatively under-explored. Objective: To determine if modulation of brain copper level affects brain tau pathology and/or associated cognitive impairment. Methods: We tested the hypothesis that brain copper modulates tau pathology by manipulating brain levels of copper in the PS19 transgenic mouse model of tau pathology. We treated PS19 and wild-type mice with oral zinc acetate, an established therapy for long term control of excess brain copper, and examined treatment effects upon brain copper, brain tau, NFT-like pathology, and spatial memory. We treated a second cohort of mice with exogenous dietary copper in order to evaluate whether excess environmental copper promotes brain tau pathology. Results: Copper-lowering with oral zinc attenuated spatial memory impairment in female but not male PS19 mice, without a significant effect upon tau pathology. Copper loading increased brain copper, but did not have an effect on brain tau pathology or spatial memory function. Conclusion: These findings suggest that a strategy to lower brain copper may be viable for symptomatic benefit in the setting of tau neuropathology, but unlikely to have robust effects on the underlying pathology. These findings are consistent with dietary or other exogenous copper being unlikely to promote tau pathology.
Maybe tainted data: Theory and a case study
Authors: Skalka Christian , Amir-Mohammadian Sepehr , Clark Samuel
Published: April 2020

Dynamic taint analysis is often used as a defense against low-integrity data in applications with untrusted user interfaces. An important example is defense against XSS and injection attacks in programs with web interfaces. Data sanitization is commonly used in this context, and can be treated as a precondition for endorsement in a dynamic integrity taint analysis. However, sanitization is often incomplete in practice. We develop a model of dynamic integrity taint analysis for Java that addresses imperfect sanitization with an in-depth approach. To avoid false positives, results of sanitization are endorsed for access control (aka prospective security), but are tracked and logged for auditing and accountability (aka retrospective security).

We show how this heterogeneous prospective/retrospective mechanism can be specified as a uniform policy, separate from code. We then use this policy to establish correctness conditions for a program rewriting algorithm that instruments code for the analysis. These conditions synergize our previous work on the semantics of audit logging with explicit integrity which is an analogue of noninterference for taint analysis. A technical contribution of our work is the extension of explicit integrity to a high-level functional language setting with structured data, vs. previous systems that only address low level languages with unstructured data. Our approach considers endorsement which is crucial to address sanitization. An implementation of our rewriting algorithm is presented that hardens the OpenMRS medical records software system with in-depth taint analysis, along with an empirical evaluation of the overhead imposed by instrumentation. Our results show that this instrumentation is practical.
GRA method for waste incineration plants location problem with probabilistic linguistic multiple attribute group decision making
Authors: Lei Fan , Lu Jianping , Wei Guiwu , Wu Jiang , Wei Cun , Guo Yanfeng
Published: April 2020

In this paper, we provide the probabilistic linguistic multiple attribute group decision making (PL-MAGDM) with incomplete weight information. In such method, the linguistic information firstly is shifted into probabilistic linguistic information. For obtaining the weight information of the attribute, two optimization models are built on the basis of the basic idea of grey relational analysis (GRA), by which the attribute weights can be obtained. Then, the optimal alternative is obtained through calculating largest relative relational degree from the probabilistic linguistic positive ideal solution (PLPIS) which considers both the largest grey relational coefficient (GRC) from the PLPIS and the smallest GRC form probabilistic linguistic negative ideal solution (PLNIS). Finally, a case study for waste incineration plants location problem is given to demonstrate the advantages of the developed methods.
Smoking, vaping and hospitalization for COVID-19
Authors: Farsalinos Konstantinos , Barbouni Anastasia , Niaura Raymond
Published: April 2020

The study purpose was to examine the prevalence of current e-cigarette use and current smoking among hospitalized patients with COVID-19 in China, considering the high population smoking prevalence in the country (26.6%, 50.5% in males and 2.1% in females).
A systematic research of the literature (PubMed) was performed on April 1. Out of 432 studies, we identified 13 studies examining the clinical characteristics of a total of 5960 hospitalized COVID-19 patients that presented data on the smoking status. No study reported e-cigarette use among COVID-19 patients. The prevalence of current smoking ranged from 1.4% to 12.6%. The random effect pooled prevalence of current smoking was 6.5% (95%CI: 4.9-8.2%).
This preliminary analysis does not support the argument that current smoking is a risk factor for hospitalization for COVID-19. Instead, these consistent observations, which are further emphasized by the low prevalence of current smoking among COVID-19 patients in the US (1.3%), raises the hypothesis that nicotine may have beneficial effects on COVID-19. This could be attributed to its immunomodulatory effects and its interaction with the renin-angiotensin system. However, other confounding factors need to be considered and the accuracy of the recorded smoking status needs to be determined. However, the results were remarkably consistent across all studies and were recently verified in the first case series of COVID-19 cases in the US.
In conclusion, the generalized advice to quit smoking as a measure to improve health risk remains valid, but no recommendation can currently be made concerning the effects of smoking on the risk of hospitalization for COVID-19. No studies recording e-cigarette use status among hospitalized COVID-19 patients were identified. Thus, no recommendation can be made for e-cigarette users. While the data are still preliminary, nicotine should be urgently examined as a potential therapeutic tool in COVID-19.

Keywords. SARS-CoV-2, COVID-19, nicotine, smoking, hospitalization, electronic cigarette.
Smoking, vaping and hospitalization for COVID-19
Authors: Farsalinos Konstantinos , Barbouni Anastasia , Niaura Raymond
Published: April 2020

The study purpose was to examine the prevalence of current e-cigarette use and current smoking among hospitalized patients with COVID-19 in China, considering the high population smoking prevalence in the country (26.6%, 50.5% in males and 2.1% in females).
A systematic research of the literature (PubMed) was performed on April 1. Out of 432 studies, we identified 13 studies examining the clinical characteristics of a total of 5960 hospitalized COVID-19 patients that presented data on the smoking status. No study reported e-cigarette use among COVID-19 patients. The prevalence of current smoking ranged from 1.4% to 12.6%. The random effect pooled prevalence of current smoking was 6.5% (95%CI: 4.9-8.2%).
This preliminary analysis does not support the argument that current smoking is a risk factor for hospitalization for COVID-19. Instead, these consistent observations, which are further emphasized by the low prevalence of current smoking among COVID-19 patients in the US (1.3%), raises the hypothesis that nicotine may have beneficial effects on COVID-19. This could be attributed to its immunomodulatory effects and its interaction with the renin-angiotensin system. However, other confounding factors need to be considered and the accuracy of the recorded smoking status needs to be determined. However, the results were remarkably consistent across all studies and were recently verified in the first case series of COVID-19 cases in the US.
In conclusion, the generalized advice to quit smoking as a measure to improve health risk remains valid, but no recommendation can currently be made concerning the effects of smoking on the risk of hospitalization for COVID-19. No studies recording e-cigarette use status among hospitalized COVID-19 patients were identified. Thus, no recommendation can be made for e-cigarette users. The above-mentioned observations, together with the potential mechanisms through which nicotine interacts with the inflammatory process and the renin-angiotensin-aldosterone axis involved in the development of COVID-19, warrant an urgent investigation of the clinical effects of pharmaceutical nicotine on COVID-19 susceptibility, progression and severity.

Keywords. SARS-CoV-2, COVID-19, nicotine, smoking, hospitalization, electronic cigarette.
DEFICIT IN STATIC GRAIN STORAGE CAPACITY IN THE STATE OF GOIÁS IN THE 2016/17 HARVEST
Authors: Da Silva Berti Mariana Pina , Guimaraes André Felippe Monteiro , Arruda Natalia , Berti Christian Luis Ferreira
Published: April 2020

The Central-West region has been highlighted as the largest agricultural center in the country, accounting for 42% of national grain production. Goiás State represented an amount of 18.9 million tons in the last harvest. Despite the large production, a problem which affects the negotiations and the quality of the harvested grains is storage. A static capacity of 20% higher than grain production is recommended. The objective of this work was to evaluate the storage capacity of grains in the State of Goiás and their respective mesoregions using a comparison with the agricultural production of the Center-West region. The deficit in the static storage capacity of grain in Goiás for the 2016/17 harvest was 25.17% in relation to grain production, since the recommended amount for safe storage is 20% higher than production, which indicates the need for a 45.17% increase in the State’s static storage capacity to supply the demand for products throughout the year and to support the producers so that they can be competitive in the domestic and international markets in the commodity negotiations. Public policies to support the creation and expansion of storage are necessary, since the investment made in the structures is high and the return of spending is not immediate.
COVER CROPS CHANGE THE PHYTOSOCIOLOGY OF WEEDS AND THE BANANA YIELD
Authors: Ávila Jorgiani , Andrade Maria Gabriela Oliveira , Vendruscolo Eduardo Pradi , Martins Jordana Dias , Lima Sebastião Ferreira
Published: April 2020

This work aimed to evaluate the phytosociology of weeds and the fruit yield of banana (cv. Tropical) in different soil coverings. The experimental design used was randomized blocks, with eight treatments and three replications. The treatments consisted of sowing of Canavalia ensiformis, Cajanus cajan, Crotalaria juncea, Stylosanthes 'Campo Grande', Crotalaria spectabilis, Sorghum bicolor, and Phaseolus lunatus between the rows of the banana trees. A control treatment was also used without cover crops. Weed phytosociology was evaluated in four treatments. The number of hands per bunch, the number of fruits per hand, the number of fruits per bunch, and the fruit yield were estimated in all treatments. In the phytosociological survey, 23 species were identified, in 13 families, especially Asteraceae and Poaceae families. Compared to the control, the coverage with C. cajan, C. juncea, and C. ensiformis provided a reduction in weed density of 108%, 71.7%, and 14.6%, respectively. C. ensiformis and C. cajan provided the highest yield of banana fruits, with an increase of 51.2% about the control. It is concluded that C. ensiformis and C. juncea provided the most significant suppression of weeds, while C. cajan and C. ensiformis provided the highest fruit yield.
Del personalismo a la acción política
Authors: Van Rompuy Herman
Published: April 2020

El 7 de diciembre de 2009, el entonces primer ministro belga, Herman Van Rompuy, en el marco de las “Grandes Conferencias Católicas” de Bruselas pronunció la disertación “Del personalismo a la acción política”. El 17 de noviembre de ese año los veintisiete jefes de Estado y de gobierno de la Unión Europea habían elegido a Van Rompuy como primer presidente del Consejo europeo. Nacido en 1947 en Flandes y doctorado en ciencias económicas en la Universidad Católica de Lovaina, Van Rompuy es un pensador político personalista en la línea de M. Scheler, J. Maritain, E. Mounier o P. Ricoeur. En su conferencia trató sobre la importancia del personalismo para fundar y orientar la acción política.
"The MDGs after the Crisis"
Authors: Romero Rodríguez José Juan
Published: April 2020

Reseña de la obra de: WORLD BANK (2010) The MDGs after the Crisis (Global Monitoring Report 2010), Washington, World Bank, 170 pp.
"El cambio climático: análisis y política económica. Una introducción"
Authors: Amador Hidalgo Luis
Published: April 2020

Reseña de laobra de: VEGARA, J. M., (director) y otros (2009) El cambio climático: análisis y política económica. Una introducción, La Caixa (Estudios Económicos 36), 181 pp.
"Mobbing, acoso laboral y acoso por razón de sexo: guía para la empresa y las personas trabajadoras"
Authors: Trechera Herreros José Luis
Published: April 2020

Recensión de la obra de: VELASCO PORTERO, Mª. T. (Dir.) (2010) Mobbing, acoso laboral y acoso por razón de sexo: guía para la empresa y las personas trabajadoras. Madrid, Tecnos, 152 pp.
"Lecciones de economía española"
Authors: Rodero Franganillo Adolfo
Published: April 2020

Reseñas de la obra de: FUENTES QUINTANA, E. (2009) Lecciones de economía española. Madrid, AECA, 328 pp.
Enfoque de derechos humanos en el desarrollo. Aspectos teóricos y metodológicos
Authors: Sánchez Moreno Manuel
Published: April 2020

El texto ofrece una breve retrospectiva del enfoque de derechos humanos, sus mitos, sus hitos, sus luchas y su integración en el desarrollo. A lo largo del mismo se repasa la confrontación teórica entre desarrollo y derechos humanos, la necesidad de incluir esta perspectiva y una aproximación metodológica sobre su inclusión en las intervenciones de desarrollo.
"(2010) I Premio Nacional de Educación para el Desarrollo Vicente Ferrer y (2011) II Premio Nacional de Educación para el Desarrollo Vicente Ferrer"
Authors: Rodero Franganillo Adolfo
Published: April 2020

Reseña de la obra de: ORTEGA CARPIO, Mª Luz (Coordinadora) (2010) I Premio Nacional de Educación para el Desarrollo “Vicente Ferrer” y (2011) II Premio Nacional de Educación para el Desarrollo “Vicente Ferrer”, Madrid, Agencia Española de Cooperación para Desarrollo (AECID), 302 y 254 pp respectivamente.
Tourism and event organization in the promotion of Vietnamese culture to Japan
Authors: Tuan Anh Luu
Published: April 2020

In the current integration as deep, cultural promotion is an indispensable trend of most countries in the world in the strategy of expanding international relations and developing countries in all aspects. Cultural promotion is capable of addressing the great challenges of the era towards sustainability, such as challenges of poverty, backwardness, instability, and conflict. When the cultures of countries are in contact with each other, the promotion of culture is really necessary. For Vietnam, cultural promotion is an effective means of cultural globalization and a positive measure for Vietnam to build and expand Vietnam's soft power to the world. In recent years, Vietnam has had many activities to promote international cooperation relations with Japan, especially in the early years of the 21st century. This article confirms in the context of the promotion strategy of Vietnamese culture to Japan, tourism activities, and event organization as important channels to attract mutual understanding between the two countries. It also helps promote the image of the country, people, and culture of Vietnam to Japan. Since then, this will create a strong international relationship between the two countries and create favorable development conditions for Vietnam in the world.
Studying about “Wood burial” - a treatment of cremation ash in Japan, today
Authors: Thi Hoai Chau Nguyen
Published: April 2020

This paper studied “wood burial”, a form of the burial of cremation ash under the tree in Japan today. Cremation has been conducted in Japan at a rate of more than 90%. Traditionally, the cremation ashes are buried in the family grave with known Japanese name as “ie haka”. But now, in Japan,  the factors influencing traditional customs such as family structure, the proportion of young and old people, religious consciousness... are changing. This led to new trends and changes in the culture of treatment of cremated remains. Among that, “wood burial” has emerged and become increasingly popular.  In general, the “wood burial” in Japan has many common features such as having harmony with nature, using trees instead of artificial gravestones, etc. in the general trend in the world. Besides, through my study,  in the particular context of Japan, the Japanese style wood burial, inheriting traditional characteristics such as burying the cremated ashes in the family unit (like family grave),  the permanence of grave,etc...has been clarified. Like that, inheriting the previous studies, this paper did a research about the background, characteristics, popularity… of the “wood burial” in Japan. It is also a noticeable topic of having attracted attention from various viewpoints nowadays. Through this, it is possible to understand Japanese burial culture, the culture of family, ancestor worship, etc. And relating to Vietnam, it is also a meaningful topic in the background that cremation has been increasingly accepted in Vietnam, and based on that, in the culture of burial, ancestor worship custom, …the change has been happening. Through the study, the author hopes to contribute to providing the knowledge systematically about this new topic in Vietnam. In this paper, through fieldwork research of the author, clarifying the characteristic, the acceptance and performance of wood burial,…, and through it, making clear the culture of treatment of cremation ashes, the change of family structure, ancestor worship, the concept of patriarchy... in Japan nowadays, is the purpose of my research. This topic has almost not been studied in Vietnam systematically and is meaningful in the context cremation is increasingly accepted, and brings changes in burial culture, the ancestor worship… in Vietnam today.
Benefícios da implantação do planejamento e controle da produção (PCP): um estudo de caso em uma empresa de confecção
Authors: Machado Ana Carolina Benevenuto
Published: April 2020

Este artigo tem como objetivo descrever a implantação do PCP em uma empresa de confecção e apresentar quais os benefícios essa ferramenta pode trazer, porém existem dificuldades que podem atrapalhar o processo de implantação. Para isso, foi realizada uma pesquisa descritiva com abordagem qualitativa de caráter exploratório através de um estudo de caso. A empresa em estudo não possui um planejamento e controle da produção bem estruturado, e foi possível perceber que a maior dificuldade na implantação do PCP encontra-se na resistência, por parte da diretoria, em mudar os processos. Portanto, foi possível concluir que a implantação do PCP na indústria de confecção irá controlar e programar a produção da empresa, também ajudará na rotina de trabalho, garantindo maior qualidade no produto final, sem atrasos, e consequentemente, manterá a empresa competitiva no mercado.

Palavras chave: Planejamento e Controle da Produção, Implantação, Dificuldades, Benefícios.
A influência das Redes Sociais no discurso do sujeito da Pós-modernidade: O dialogismo das relações que se instauram entre enunciados
Authors: Silva Rita Barcelos da , Araújo Michell Pedruzzi Mendes , Picinati Suander Leonardo Doná , Bof Roberta Decarli
Published: April 2020

O sujeito da atualidade experiencia dos estímulos tecnológicos e culturais que reverberam de uma nova era essencialmente informativa. O discurso do homem contemporâneo sofre com as influências de novos padrões de comportamento, que atravessam a história e os contextos, seja no ambiente familiar, de trabalho ou demais palcos da vida. Vivemos a instabilidade de uma vida moderna fragmentada, que afeta as relações discursivas dos indivíduos. Com o acesso facilitado aos diversos veículos de comunicação, eventos hostis acabam por virem implícitos em discursos mal-intencionados. Nesse sentido, o estudo em questão objetiva analisar como o sujeito imerso na tecnologia é influenciado e influência pelos/nos diversos atravessamentos. Concorrem como objetivos específicos: compreender como a sociedade tem reagido aos diferentes estímulos recebidos pelas mídias sociais; refletir sobre as transformações nos processos sócio comunicacionais do sujeito em seu contexto histórico; analisar os preconceitos instalados nos discursos veiculados nas mídias sociais. O trabalho é de base qualitativa com proposição de pesquisa bibliográfica. Como aporte teórico, buscaram-se as contribuições de Brait (2009), Bhabha (1998), Bauman (1999), Hall (2001), Rosemberb (2006) dentre outros. Por intermédio do estudo realizado, é percebido que, frequentemente, pessoas se apropriam das mídias digitais, para externarem discursos depreciativos e antiéticos, ou até mesmo propagarem inverdades. Na contramão dessa realidade inoportuna, advogamos que as ferramentas digitais, enquanto inovações tecnológicas, podem propiciar o estreitamento das relações humanas por intermédio dos discursos, considerando a pluralidade e as peculiaridades socioculturais e sociolinguísticas de cada indivíduo.

Palavras-chave: Discurso, mídias digitais, pluralidade.
Tradisi Budaya Masyarakat Islam di Tatar Sunda (Jawa Barat)
Authors: Sujati Budi
Published: April 2020

Di era globalisasi ini arus perubahan budaya lintas negara sangat cepat terjadi. Di satu sisi sangat mengkhawatirkan dan satu sisi lain menggembirakan. Kekhawatiran tersebut dirasakan karena perubahan budaya bersifat Trans-Nasional akan mengubah struktur identitas budaya-budaya lokal yang sudah mapan digantikan dengan budaya yang lebih bersifat radikal, tanpa kompromi. Menggembirakannya adalah budaya lokal yang dapat bertahan dari hembusan badai yang menghadang dengan sangat kencang akan menjadi model dan contoh dari bangsa-bangsa lain untuk dapat belajar dari budaya kita. Tulisan ini akan menjelaskan bagaimana sebuah budaya lokal di Tatar Sunda (Jawa Barat) mampu berakulturasi dengan agama Islam yang dianut oleh masyarakat Sunda sebagai agama mayoritas menjadikan agama Islam dijalankan dalam aspek kehidupan berbaur dengan budaya setempat dengan mengakar kuat bahwa Islam adalah Sunda dan Sunda adalah Islam. Penelitian ini bersifat deskriptif dengan metodologi kualitatif. Digunakannya metode ini agar mudah menjelaskan (to eksplanation)  suatu fenomena yang terjadi di masyarakat Tatar Sunda (Jawa Barat) dengan menggunakan kajian budaya dengan tahap heuristik, kritik, interpretasi dan historiografi.