bluuebunny/crossref_metadata_2025 huggingface dataset:
Expediente
Authors: Adriane C. Kasprowicz
Published: June 2022

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Editorial
Authors: Adriane kasprowicz
Published: June 2022

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Almanca Öğretmeni Adaylarının Uzaktan Eğitim Memnuniyet Algıları Üzerine Bir Araştırma
Authors: Arslan Çavuşoğlu Ayşe , Tepebaşılı Fatih
Published: June 2022

Bu çalışmada Covid-19 salgın dönemi uzaktan eğitim alan Alman Dili Eğitimi Bölümü öğrencilerinin uzaktan eğitime yönelik memnuniyet algılarını tespit etmek amaçlanmıştır. Bu amaç doğrultusunda bir devlet üniversitesi Eğitim Fakültesi Yabancı Diller Eğitimi Alman Dili Eğitimi Bölümü’nde öğrenim gören 80 üniversite öğrencisine Uzaktan Eğitim ile ilgili memnuniyet anketi uygulanmıştır. Anketten online olarak elde edilen veriler frekans ve yüzde gibi tanımlayıcı istatistikler yoluyla R Studio programında analiz edilmiştir. Araştırma sonucunda öğrencilerin uzaktan eğitim sistemini çok fazla benimsemedikleri görülmüştür. Almanca eğitiminin uzaktan sürdürülmesine ilişkin video kayıtlarının, esnek eğitim olanaklarının ve zamandan tasarrufun olumlu olduğu görülürken, internete ulaşamama, teknik sorunlar ve sosyal olarak izole edilmiş olma gibi konular olumsuz yönler olarak tespit edilmiştir. Araştırmanın bir diğer dikkat çekici sonucu ise öğrencilerin yüz yüze eğitimde olduğu kadar olmasa da öğretim üyeleri ile iletişim kurmakta çok zorlanmadıklarını belirtmeleridir. Anketi oluşturan her bölümde kararsız öğrencilerin fazla olması araştırmanın bir diğer çarpıcı sonucudur. Bu sonuç, uzaktan eğitimde teknik sorunların giderilmesi ve uzaktan eğitimin iyileştirilmesi durumunda kararsız öğrencilerin uzaktan eğitime uyum sağlayabilecekleri ve uzaktan eğitimden memnun olabileceklerini göstermektedir. Bu tür çalışmalar diğer üniversitelerde de yürütülürse ve ortak sorunlar tespit edilirse sorunların üstesinden gelmede ve eğitim siteminin iyileştirilmesinde ortak adımlar atılabilir.
In Transfusion-Dependent Thalassemia Children, Increased Iron
Overload is Associated with Lower Serum Alpha-Klotho, Which is
Strongly Associated with Lower Total and Ionized Calcium
Concentrations
Authors: Moustafa Shatha Rouf , Al-Hakeim Hussein Kadhem , Alhillawi Zainab Hussein , Maes Michael
Published: June 2022

Background:

Patients with transfusion-dependent thalassemia (TDT) show
disorders in calcium metabolism. The α-Klotho protein is predominantly expressed in
tissues that are involved in calcium homeostasis, and lowered levels are associated with
bone disease. The aim of the study is to examine the associations between low α-Klotho
status and calcium metabolism in relation to iron status in children with TDT.

Methods:

Calcium, α-Klotho, parathyroid hormone (PTH), calcyphosin, vitamin D3,
phosphorous, fibroblast growth factor receptor 2 (FGFR2), as well as iron and erythron
biomarkers were measured in 60 children with TDT and 30 healthy control children.

Results:

A meaningful part of TDT patients showed lowered α-Klotho levels, and those
children also showed low serum total and ionized calcium concentrations. TDT patients
showed increased PTH, FGFR2, and calcyphosin and lowered vitamin D3 as compared
with healthy children. The α-Klotho levels were significantly correlated with total and
ionized calcium (positively) and with iron overload and transfusions biomarkers
(inversely). Partial Least Squares path analysis showed that 40.1% of the variance in
serum total calcium could be explained by the regression on α-Klotho, vitamin D3 (both
positively), and calcyphosin (inversely) and that the effects of the latter are mediated by
iron overload and the number of blood transfusions.

Conclusion:

In conclusion, the iron overload in TDT and its consequences may induce
lowered levels of α-Klotho which in turn may lead to lower calcium thereby explaining at
least in part the effects of TDT on bone metabolism including spontaneous pathological
fractures, osteoporosis, osteopenia, and skeletal deformities.
Application of Induced Pluripotent Stem Cells in Moyamoya Disease:
Progress and Promises
Authors: Xue Yimeng , Zhang Qian , Wang Lin-Jian , Tu Wen-Jun , Zhao Jizong
Published: June 2022

Moyamoya disease (MMD) is a chronic steno-occlusion cerebrovascular disease accompanied
by the formation of the abnormal vascular network at the base of the brain. The etiology of MMD is not
fully clarified. Lack of pathological specimens hinders the research progress. Induced pluripotent stem
cells (iPSC) derived from patients with outstanding differentiation potential and infinite proliferation
ability could conquer the problem of insufficient samples. The technology of iPSC holds the promise of
clarifying the underlying molecular mechanism in the development of MMD. In this review, we summarized
the latest progress and difficulties in the research of mechanism and detailed the application of iPSC
in MMD, aiming to provide an outlook of iPSC in molecular mechanism and novel therapies of MMD.
A Novel Compound Heterozygous Gene Mutation of Dolichol Kinase Deficiency
(DOLK-CDG)
Authors: Wang Caixia , Yu Shufeng , Zhang Ying , Chen Zhihong , Song Jiye
Published: June 2022

Background:

Congenital disorder of glycosylation caused by mutation of the
DOLK(DOLK-CDG) is a group of rare autosomal recessive diseases with an early-onset age and
poor prognosis. DOLK-CDG can cause the dysfunction of multiple systems and organs such as
the heart, skin, nerves, and bones.

Case Presentation:

We report a child with DOLK-CDG diagnosed and treated in the Affiliated
Hospital of Qingdao University. The child was born with neonatal asphyxia, Ichthyoid rash, and
congenital heart disease. His fingers of both the hands looked like lotus roots, and the palm and
foot were covered by a white membrane. He was hospitalized with a severe infection at 4 months
after birth. Physical examination showed that he was complicated with development delay and
hypotonia. He experienced convulsions 1 hour after admission and died of multiple organ failure
2 hours after admission. Blood samples were taken for genetic testing before the child died. The
results showed that there was a novel compound heterozygous mutation in DOLK, c.1268C＞G
(P.P423R）and c.1581_1583del (P.527_528del).

Conclusion:

This mutation is new and not included in the human gene mutation library. The
discovery of the novel mutation broadened the mutation spectrum of DOLK. At the same time,
we sorted out the DOLK-CDG gene mutation sites and related clinical manifestations reported
by August 2021 through a literature review.
Novel Methodology for Synthesis and Computational Analysis of Zinc
Complexes of Isatin Derivatives and Screening their Biological Activity
Authors: Goel Akriti , Aggarwal Navidha , Jain Sandeep
Published: June 2022

Background:

Due to arising threats of microbial infectious diseases in the human population, and the development of resistance against therapeutics, novel medicinal agents are required to counteract antimicrobial resistance. Heterocyclic rings such as indole or pyrrole, have been acknowledged to possess various biological properties like antimicrobial, anticancer, antiviral, antitubercular, etc and metals such as platinum, vanadium, zinc, selenium, etc. also show therapeutic actions. Thus, this work focuses to turn heterocyclic ring compound (isatin) and metal (zinc) into a drug having antimicrobial potential.

Objective:

The objective of the study was to synthesize zinc complexes of isatin Schiff bases and evaluate for antibacterial and antifungal activity.

Methods:

Herein, the conventional method was used for the synthesis of isatin Schiff bases from isatin and different monosubstituted amines. Then, zinc complexes were prepared by using isatin Schiff bases and zinc acetate. Physicochemical characteristics such as Rf value and melting point were determined by TLC and decibel melting point apparatus respectively. All the complexes were characterized by FT-IR and 1H NMR techniques. Further, the final zinc complexes were screened for antimicrobial potential by the serial dilution method. Some computational studies were also done with the help of MOPAC 2016.

Result:

In the present work, 14 complexes of zinc are obtained in harmonious yield from isatin Schiff bases using zinc acetate. Amongst the studied complexes, Z-3, Z-4, and Z-12 depicted maximum antimicrobial activity.

Conclusion:

14 complexes of zinc were prepared by using 14 isatin Schiff bases which were in turn prepared by isatin and different mono-substituted amines. Characterization of these complexes was done by using FT-IR and 1H NMR. All prepared metal complexes were obtained in appropriate yield. The synthesized complexes were screened for their antimicrobial potential.
Effects of Drugs and Chemotherapeutic Agents on Dental Implant Osseointegration:
A Narrative Review
Authors: Mohammadi Aida , Dehkordi Nazanin Roqani , Mahmoudi Sadaf , Rafeie Niyousha , Sabri Hamoun , Valizadeh Maryam , Poorsoleiman Taniya , Jafari Aryan , Mokhtari Alireza , Khanjarani Arshia , Salimi Yasaman , Mokhtari Melika , Deravi Niloofar
Published: June 2022

Background:

Dental implants have been one of the most popular treatments for rehabilitating individuals with single missing teeth or fully edentulous jaws since their introduction. As more implant patients are well-aged and take several medications due to various systemic conditions, clinicians should be mindful of possible drug implications on bone remodeling and osseointegration.

Objective:

The present study aims to study and review some desirable and some unwelcomed implications of medicine on osseointegration.

Methods:

A broad search for proper relevant studies were conducted in four databases, including Web of Science, Pubmed, Scopus, and Google Scholar.

Results:

Some commonly prescribed medicines such as nonsteroidal anti-inflammatory drugs (NSAIDs), glucocorticoids, proton pump inhibitors (PPIs), selective serotonin reuptake inhibitors (SSRIs), anticoagulants, metformin, and chemotherapeutic agents may jeopardize osseointegration. On the contrary, some therapeutic agents such as anabolic, anti-catabolic, or dual anabolic and anti-catabolic agents may enhance osseointegration and increase the treatment’s success rate.

Conclusion:

Systemic medications that enhance osseointegration include mineralization promoters and bone resorption inhibitors. On the other hand, medications often given to the elderly with systemic problems might interfere with osseointegration, leading to implant failure. However, to validate the provided research, more human studies with a higher level of evidence are required.
A experiência da viagem, da (des)territorialização e do conflito nos romances de Luís Cardoso
Authors: D'Alte Pedro
Published: June 2022

Nas narrativas de Luís Cardoso, as movimentações, efectivas ou simbólicas, sãopoderosas e logram colocar em evidência todo o tipo de polarizações: diferenças étnicas ereligiosas; clivagens sociais e políticas; o mito e facto; a possibilidade e a impossibilidade. Oexercício, que aqui se apresenta, analisa o percurso evolutivo das personagens masculinascardosianas (Takas, Lucas Santiago, Pigafetta e Evaristo de Aquino) à luz dos binómiosanteriores e, também, enquadrando tais deslocações em diferentes planos: o da própriaviagem; o da fragmentação do eu; o da identidade e o do exílio. É de crer que a análise dasdiferentes personagens permita revisitar um mosaico polifónico sobre o que foram asvivências e as experiências de muitos timorenses nos últimos quartéis do século XX e nasprimeiras décadas do presente século.
Ogum, os Iaôs e as Demandas. Ancestralidade afro-brasileira em Os pastores da Noite, de Jorge Amado
Authors: Tannus Gustavo
Published: June 2022

A literatura reflete a identidade e contribui para sua construção. O trabalho de Jorge Amado não é diferente; representa aspectos da cultura, como cultura oficial e cultura minoritária; entre o saber oficial e o tradicional, o mundo negro e o universo negro, entre a história e a memória, etc. Neste trabalho estudaremos a relação entre cultura e religiosidade, no segundo capítulo do referido livro. Pretendemos, portanto, observar a ancestralidade como um valor nas comunidades afro-brasileiras, a partir das quais partimos das perspectivas de Leite (1996), Martins (2002), Cunha Jr. (2010) e Rosa (2013).
“No pictures, please”: A viagem de José Luís Peixoto à Coreia do Norte A fotografia como um certificado de presença
Authors: Almeida Catarina Nunes de
Published: June 2022

Em 2012, o escritor português José Luís Peixoto viajou para a Coreia do Norte, uma experiência que descreveu na obra intitulada Dentro do Segredo. Ao longo do relato, o narrador problematiza o uso da fotografia como meio de verificação e legitimação duma viagem. Poucas fotografias produzidas na Coreia do Norte abrem espaço à improvisação e o narrador mostra-se sensível a esse facto. Ele reconhece que diante da sua lente fotográfica existe sempre uma outra lente – a de um regime político austero. O artigo explora justamente a relação entre palavras e imagens presente no relato de Peixoto. Procura demonstrar como as fotografias – sejam elas produzidas ou observadas – constituem formas falíveis de representação do mundo, dificultando eventuais tentativas de descrever fielmente o Outro. Este estudo partirá assim do ponto de vista do autor que considera que qualquer imagem capturada naquele espaço exige uma dupla descodificação.
Gestos da dissimulação. O melodrama negociado em Helena (1876), de Machado de Assis
Authors: Peres Marcos Flamínio
Published: June 2022

Obra da primeira fase da produção machadiana, Helena agradou a crítica num primeiro momento por aproximar-se do melodrama, gênero de muita aceitação no século XIX, embora ao longo do século XX tenha passado a ser criticado por não cumprir as expectativas que se esperava do gênero, sobretudo ao conceber um vilão que está longe de encarnar plenamente a polarização entre extremos, como bem e mal, puro e impuro, etc.. No entanto, tem se prestado pouco atenção à heroína que dá título ao romance, que, embora se apresente como a típica vítima inocente perseguida pelo malfeitor, ela apresenta uma cisão interna inaceitável para o gênero, a crermos em seus principais estudiosos (Heilman, Sharp, Brooks). Transigindo com o vilão, ela acaba por tentar manipular personagens e enredo em seu próprio benefício, colocando seriamente em risco os fundamentos do gênero. Isso sugere mais do que uma falha de concepção por parte de Machado, mas, sim, um questionamento deliberado ao gênero e da própria natureza da narrativa, questionamento que será deliberadamente aprofundado em seus romances maduros, como Dom Casmurro e Esaú e Jacó.
Uma Viagem à Índia enquanto arte de viver
Authors: Meneses Pedro Manuel
Published: June 2022

Uma Viagem à Índia de Gonçalo M. Tavares é uma epopeia que parodia Os Lusíadas de Luís de Camões, o texto-fonte da identidade portuguesa. Não se debruça sobre questões identitárias portuguesas. Bloom é português, mas a obra concentra-se em investigar o geograficamente invariável no comportamento humano. O destino de Bloom, jovem adulto que faz uma viagem iniciática, depois de um acontecimento trágico, permite refletir sobre o uso ético da potência do corpo, o que faremos ensaiando ligações intertextuais com O Osso do Meio. Não se dedicou a uma ocupação, nem assumiu a responsabilidade pelo crime que cometeu. No final da obra, revelará uma indiferença ético-moral perigosa.
Dooppraxis en gereformeerde theologie
Authors: Pleizier T.T.J. , Moehn W.H.Th.
Published: June 2022

Christian baptism is a so-called concentrated practice; soteriology, ecclesiology and spirituality come together in this central Christian sacrament. Many questions surround the practice of baptism in a late-modern secularised Dutch society. For example, how is classic Reformed theology received in contemporary congregations? We asked four ministers to write a reflection on issues that are significant in the practice of baptism in their congregations. This article reports on their reflections and points to three areas in which the practice of baptism in contemporary Reformed churches needs further theological work: the didactic structure of Reformed baptismal practices, the divergence between personal spirituality and the pivotal notion of ‘covenant’ in Reformed theology, and the inherent theological understanding of the reality of salvation in relation to baptismal practices.
FAMILIA LEGUMINOSAE: SUBFAMILIA CAESALPINIOIDEAE
Authors:   Instituto de Ecología, A.C. Centro Regional del Bajío, Rzedowski Jerzy , Calderón de Rzedowski Graciela ,   Instituto de Ecología, A.C. Centro Regional del Bajío
Published: June 2022

Esta es una de las tres familias de plantas vasculares mejor representadas a nivel mundial. Se calculan alrededor de 550 géneros y unas 12000 a 17000 especies de distribución cosmopolita, principalmente en las regiones cálidas y templadas. Entre las leguminosas se cuenta con elementos de gran importancia económica: alimenticias, medicinales, forrajeras, empleadas a manera de abono verde, maderables, ornamentales, a la vez que otras conocidas como tóxicas, espinosas o malezas invasoras. A diferencia de algunos autores que distinguen tres familias separadas, en esta Flora se considera a las leguminosas como una sola entidad subdividida en las subfamilias Caesalpinioideae, Mimosoideae y Papilionoideae.
Análisis de precios de la ahuyama Cucurbita moschata en cinco ciudades de Colombia
Authors: Martínez Reina Antonio María
Published: June 2022

El objetivo de este trabajo fue analizar el comportamiento del precio de la ahuyama en los cinco principales mercados: Barranquilla, Cartagena, Montería, Sincelejo y Valledupar de la Región Caribe de Colombia. Los datos que se usaron fueron del Sistema de información de precios del DANE en periodos semanales durante los años 2012 al 2019. Con el uso de técnicas de cointegración, se identificaron las relaciones entre las series, igualmente se determinó la causalidad por el método de Granger. El trabajo probó que existe integración de los mercados en el proceso de formación de precios. Los resultados permiten evidenciar la integralidad de los mercados y la no presencia de causalidad entre los precios de las cinco ciudades sin que el tamaño del mercado afecte esta situación. Se concluye que, aún en ausencia de causalidad entre los mercados, estos sí están integrados en el largo plazo, lo que evidencia el cumplimiento de la ley de precio único.
Influencia del uso del suelo en la diversidad y composición de artrópodos edáficos en la Granja Tunguavita
Authors: Forero Nicolas , Serrano Pablo A. , Forero Fabio E.
Published: June 2022

La modificación del paisaje, la intensa explotación de recursos naturales mediante agricultura intensiva y el avance de la frontera agrícola da resultado la homogeneización del paisaje y alteración de condiciones fisicoquímicas del suelo. Estas alteraciones en el suelo provocan cambios en la composición y diversidad de las comunidades de artrópodos edáficos que pueden ser utilizados como herramientas de biomonitoreo y diagnostico en zonas locales. El objetivo del estudio fue evaluar la diversidad de artrópodos edáficos y su asociación a diferentes parámetros fisicoquímicos (i.e., pH, densidad real, densidad aparente, CO, MO y humedad gravimétrica y volumétrica) en tres usos del suelo (cultivo permanente, cultivo rotativo y pastoreo) en la granja experimental Tunguavita Paipa – Boyacá. Para obtener los datos de las variables biológicas y fisicoquímicas se usó la técnica de muestreo por parcela. Las muestras fueron tomadas en tres usos de suelo, cultivo permanente, cultivo rotativo y lote de ganadería. Los artrópodos edáficos y se determinó las variables fisicoquímicas en el laboratorio de suelos de la Universidad Pedagógica y Tecnológica de Colombia. La mayor diversidad de artrópodos edáficos (309 individuos), se registró en el lote de cultivo permanente, seguido del cultivo rotativo ambos con valores promedio altos de %MO (1.82 – 1.90) y %CO (1.05 – 1.10). El grupo de Oligochaeta, Diplopoda y Araneae fueron los que contribuyeron en mayor proporción a la diferenciación biológica entre usos de suelo. Los cambios en la abundancia de artrópodos edáficos, se relacionaron con % Humedad gravimétrica, %Humedad volumétrica, pH, %MO y %CO, mientras que los valores de densidad real y densidad aparente, no se correlacionaron en gran medida con los cambios de abundancia. Estas variaciones permiten la diferenciación de usos de suelo en un gradiente de intervención.
Measurement of Adherence to mHealth Physical Activity Interventions and Exploration of the Factors That Affect the Adherence: Scoping Review and Proposed Framework
Authors: Yang Yang , Boulton Elisabeth , Todd Chris
Published: June 2022

Background

Mobile health (mHealth) is widely used as an innovative approach to delivering physical activity (PA) programs. Users’ adherence to mHealth programs is important to ensure the effectiveness of mHealth-based programs.

Objective

Our primary aim was to review the literature on the methods used to assess adherence, factors that could affect users’ adherence, and the investigation of the association between adherence and health outcomes. Our secondary aim was to develop a framework to understand the role of adherence in influencing the effectiveness of mHealth PA programs.

Methods

MEDLINE, PsycINFO, EMBASE, and CINAHL databases were searched to identify studies that evaluated the use of mHealth to promote PA in adults aged ≥18 years. We used critical interpretive synthesis methods to summarize the data collected.

Results

In total, 54 papers were included in this review. We identified 31 specific adherence measurement methods, which were summarized into 8 indicators; these indicators were mapped to 4 dimensions: length, breadth, depth, and interaction. Users’ characteristics (5 factors), technology-related factors (12 factors), and contextual factors (1 factor) were reported to have impacts on adherence. The included studies reveal that adherence is significantly associated with intervention outcomes, including health behaviors, psychological indicators, and clinical indicators. A framework was developed based on these review findings.

Conclusions

This study developed an adherence framework linking together the adherence predictors, comprehensive adherence assessment, and clinical effectiveness. This framework could provide evidence for measuring adherence comprehensively and guide further studies on adherence to mHealth-based PA interventions. Future research should validate the utility of this proposed framework.
Borderland, Migration and the Question of National Identity in Nigeria, 1914-1991
Authors: Abubakar (Ph.D) Bello Zakariya , Adihikon (Ph.D) Tanko A. , Ali HamisuSani
Published: June 2022

Prior to the European conquest of Africa, the area of study was made up of various political entities with different ethnic and religious backgrounds. However, the British colonization and subsequent 1914 amalgamation brought all ethnic nationalities and regions together to form what is now Nigeria. Nevertheless, the nature of political boundaries in Africa separated people with common ethno-religious and political experiences. Thus, most of the people at the borderlands freely migrate to and from Nigeria to neighbouring countries without respect for immigration laws which made it difficult for national identity in the West African sub-region. Therefore, nationalism and independence in Nigeria/Africa have failed to correct such colonial mistakes which made it difficult to address the question of national identity. Above all, the National Identity Management Commission (NIMC) which was established by the NIMC Act No. 23 of 2007 to address the issue of immigrants is still battling the question of national identity.
Lista de revisores 2021
Authors: Research Journal UNED
Published: June 2022

Lista de revisores 2021
Trends in anti-infective use during pregnancy in France between 2010 and 2019: A nationwide population-based study.
Authors: Tubiana sarah , Sibiude Jeanne , Herlemont Philippe , DROUIN Jérôme , Picone O. , DUVAL Xavier , Weill Alain , Zureik Mahmoud , DRAY-SPIRA Rosemary
Published: June 2022

Aim. To describe the trends in anti-infective use during pregnancy
between 2010 and 2019 and determine whether they were prescribed
according to drug fetal safety international classification systems.
Methods. We conducted a population-based, nationwide study using the
French national health data system including all pregnancies ended
between 2010 and 2019. Anti-infective were considered according to their
pharmacological group and potential harmful risk using the Australian
and Swedish classification systems. Prevalence rate was estimated
annually and by trimester. Average annual percent change (AAPC) and 95%
confidence intervals (CI) were calculated using Joinpoint regression.
Results. Among 7,571,035 pregnancies, 3,027,031 (40.0%) received ≥ 1
antibacterial. This proportion decreased significantly from 41.5% in
2010 to 36.1% in 2019 (AAPC=-1.7%, [95%CI, -2.5% to -1.0%]).
Conversely, use of antiviral agents increased during the 10 years’ study
period for anti-HSV agents (AAPC=4.4%, [3.7%-5.2%]), influenza
agents (AAPC=25.4%, [6.2%-48.1%]), and for HIV-antiretroviral
agents (HIV-ART) (AAPC=1.3%, [0.6%-2.0%]). Use of influenza
vaccine increased from 0.2% in 2010 to 4.2% in 2019 (AAPC=49.7%,
[95%CI, 39.3% to 60.9%]). Among all pregnancies, 0.9% had been
exposed to a potentially harmful anti-infective agent increasing from
0.7% in 2010 to 1.2% in 2019 (AAPC=6.4%, [4.4%-8.5 %]).
Conclusion. Based on more than 7 million pregnancies identified from
French nationwide data, this study showed that antibacterials are
frequently prescribed during pregnancy although their use has decreased
over the past ten years. Our results suggest that anti-infective are
generally prescribed in accordance with recommendations, with however a
potential for improvement in influenza vaccination.
Effect of parent material and atmospheric deposition on the potential pollution of urban soils close to mining areas
Authors: Vázquez-Arias Antón , Peinado Francisco Martín , Parviainen Annika
Published: June 2022

The aim of this study is to analyse the concentration of potentially
toxic elements (PTEs) in urban soils under the influence of mining
activities and to determine its sources. For this purpose, topsoil
samples of the public parks and green areas in Minas de Riotinto (a town
next to one of the largest open pit mines in the world) and Aracena (a
nearby town outside the area of influence of the mine) were collected.
The concentrations of elements of interest (Cr, Co, Ni, Cu, Zn, As, and
Pb) were determined and compared based on soil location and origin (
in-situ or ex-situ), and with the background and
regulatory levels for the region. The elemental concentrations in the
fine fraction of the soils (particles <50 µm) were also
measured. The concentrations of some PTEs (Cu, As and Pb), also found in
the dust from nearby mines, were higher in the in-situ soils of
Minas de Riotinto than in those of Aracena. The concentrations of PTEs
in ex-situ soils of both towns were much lower than in
in-situ soils, and similar between both locations, revealing the
influence of the parent material as a primary source of PTEs. However,
the concentrations of As and Cu in the ex-situ soils of Minas de
Riotinto were significantly higher than the ones in Aracena, with a
significant increase of these elements in the fine fraction both for
in-situ and ex-situ soils. These two elements are directly
related to the mining activity, implying that atmospheric deposition of
dust from the mines also contributes to increasing the concentration of
PTEs in the soils of Minas de Riotinto. These pollution sources lead to
soils with potentially dangerous concentrations of pollutants, which
should be further studied and evaluated in relation to their long-term
influence on human health.
In Vitro Fertilization with Preimplantation Genetic Testing for Aneuploidy for Infertility in China: A Cost-Effectiveness Analysis
Authors: he xuan , Wang Xiao , Shen Jiaojie , Wan Bin , Wang Yingpeng , Zhang Zhuolin , Cai Lele , Bao Yuwen , Ding Haixia , Li Xin
Published: June 2022

Objectives: To investigate the cost-effectiveness of preimplantation
genetic testing for aneuploidy (PGT-A) versus conventional technology in
in vitro fertilization (IVF) from the perspective of the healthcare
system in China. Design: Economic evaluation based on a large
multi-center randomized trial (CESE-PGS study). Population: Infertile
women with a good prognosis for a live birth in China Methods: Following
the exact steps in the IVF protocol, a decision tree model was
developed, based on the data from the CESE-PGS trial and using cost
scenarios for IVF in China. The scenarios were compared for costs per
patient and cost-effectiveness. One-way sensitivity analysis and
probabilistic sensitivity analysis were performed to confirm the
robustness of the findings. Main Outcome Measures: Costs per live birth,
Costs per patient, Incremental cost-effectiveness for miscarriage
prevention Results: The average costs per live birth of PGT-A were
estimated as ¥39230.71, which is about 16.8% higher than that of the
conventional group. Threshold analysis revealed that PGT-A would need to
increase the pregnancy rate of 26.24% to 98.24% or a cost reduction of
¥4649.29 to ¥1350.71 to achieve the same cost-effectiveness. The
incremental costs per prevented miscarriage was approximately ¥45600.23.
Probabilistic sensitivity analysis indicated a probability of 97.50%
that PGT-A is cost-effective when the willingness to pay was ¥
21,7113.00 per prevented miscarriage. Conclusions: The present
cost-effectiveness analysis demonstrates that embryo selection with
PGT‑A is not suitable for routine applications from the perspective of
healthcare providers in China, given the cumulative live birth rate
(CLBR) and the high costs of PGT‑A.
Training on the Development of Chemical Multiple Representations Integrated PowerPoint-iSpring Learning Media: a case of Chemistry Teachers in Padang
Authors: Guspatni Guspatni , Oktavia Budhi , Azra Fajriah , Azhar Minda
Published: June 2022

The training
Increasing The Competence of Science Teachers in The Batusangkar City through Technical Guidance on 21st Century Learning Implementation in Integrated Science student worksheet
Authors: Ratnawulan Ratnawulan -
Published: June 2022

One of the problems that often affects the learning process in junior high schools (SMP) is that there are still many science teachers who are not yet skilled in developing thematic Integrated Science Student Worksheets so that the meaning of integration between physics, chemistry, and biology has not been achieved. On the other hand, there needs to be an effort from the teacher, so that students can face the challenges of the 21st century. One of them is by integrating 21st century learning skills into the Student Worksheets used. The purpose of this activity is to improve teacher competence through technical guidance on the implementation of 21st century learning in Integrated Science student worksheets. The form of mentoring activities consists of several stages, namely: orientation, preparation, mentoring 1(in) ; group work. Mentoring 2 (on) in the form of monitoring in partner schools and evaluation. The results achieved from this technical guidance are an increase in the pedagogic and professional competence of teachers from moderate to good.
Caracterización de sonidos deglutorios adquiridos mediante auscultación cervical en sujetos sanos y con disfagia.
Authors: Betancur Rengifo Juan Pablo , Restrepo Uribe Juan Pablo , Pérez Giraldo Estefania , Orozco Duque Andrés
Published: June 2022

La deglución es un acto de alta complejidad neuromuscular debido a que intervienen más de 30 pares musculares y 5 pares craneales en un periodo corto de tiempo. Esta se divide en 4 etapas: pre oral, oral, orofaríngea y esofágica, una alteración en el desarrollo normal de alguna de estas fases puede desarrollar un síntoma secundario a enfermedades neuromusculares y neurogénicas que se conoce como disfagia, esta puede traer consigo muchas dificultades para quien la padece, entre esta neumonía bronquial, desnutrición, deshidratación o incluso la muerte por asfixia. La identificación de características que ayuden a reconocer dicho síntoma, además de describir correctamente el proceso deglutorio, es de gran importancia ya que los métodos existentes son invasivos. La auscultación cervical es una técnica mediante la cual se puede obtener información del cierre glótico en el proceso deglutorio por medio de señales de audio, y que puede ser analizada de manera off line. El objetivo de este estudio es evaluar diferentes métodos de caracterización de señales de auscultación cervical y desarrollar un modelo de aprendizaje automático con sonidos de eventos deglutorios segmentados de forma manual para clasificar entre sujetos de control y pacientes con disfagia orofaríngea. Los resultados mostraron, con una exactitud máxima de 75 %, que por medio de señales de auscultación cervical es posible identificar sujetos con disfagia, de igual manera se logró identificar que la potencia media de los segmentos deglutorios fue la característica con mejor rendimiento (curva ROC) y una distribución diferente entre clases según la prueba de U-Mann-Whitney, para discriminar entre sanos y pacientes en diferentes actividades deglutorias.
Pengaruh Kredibilitas dan Terpaan Iklan Gojek Versi “BTX - It's Okay To Be Lebay” di Youtube Terhadap Keputusan Menggunakan Jasa Gojek Pada Era New Normal
Authors: Lestari Astiyani , Santoso Budi
Published: June 2022

Kredibilitas adalah persepsi yang dimiliki oleh khalayak tentang komunikator. Dampak pesan terhadap khalayak dipengaruhi oleh bagaimana khalayak memandang pengirim pesan atau bagaimana kredibilitas komunikator dalam pandangan khalayak. Iklan adalah elemen komunikasi pemasaran yang persuasif, nonpersonal, dibayar oleh sponsor, dan disebarkan melalui saluran komunikasi massa untuk mempromosikan pemakaian barang atau jasa. Pengambilan keputusan diartikan sebagai proses manusia yang didasarkan pada premis nilai dan fakta serta berdasarkan fenomena personal dan sosial, yang bertujuan untuk menentukan pilihan dari berbagai pilihan untuk bergerak menuju situasi yang ideal. Judul penelitian ini adalah Pengaruh Kredibilitas dan Terpaan Iklan Gojek Versi “BTX - It's Okay To Be Lebay” Di YouTube Terhadap Keputusan Menggunakan Jasa Gojek Pada Era New Normal. Teori yang digunakan dalam penelitian ini adalah teori S-O-R dan teori AIDDA. Metode penelitian ini menggunakan pendekatan kuantitatif dengan metode survei dan pengambilan sampel menggunakan teknik purposive sampling dengan menggunakan rumus Slovin didapatkan 400 responden. Hasil dari analisis penelitian ini adalah variabel kredibilitas dan terpaan iklan, keduanya secara simultan memiliki pengaruh yang signifikan terhadap keputusan pembelian. Kesimpulan dari hasil penelitian ini ialah pada kedua variabel independen yaitu kredibilitas dan terpaan iklan Gojek versi “BTX - It's Okay to be Lebay” di YouTube terhadap variabel dependen keputusan menggunakan jasa Gojek pada era new normal terdapat pengaruh yang signifikan. Saran untuk para peneliti selanjutnya yang akan melakukan penelitian dengan objek yang sama, maka disarankan untuk mengubah variabel independen dan juga masih banyak faktor lain yang dapat mempengaruhi keputusan pembelian pengguna Gojek selain faktor kredibilitas dan terpaan iklan.
Strategi Komunikasi Corporate Social Responsibility (CSR) PT PLN (PERSERO) UIK Tanjung Jati B Terhadap Komunitas Nelayan Perairan Pulau Panjang
Authors: Setyorini Ika , Sarwo Yohanes Budi , Nugroho Abraham Wahyu
Published: June 2022

Penelitian ini bertujuan untuk mengkaji strategi komunikasi CSR (Corporate Social Responsibility) dari PT. PLN (Persero) Unit Induk Pembangkitan (UIK) Tanjung Jati B dalam mengkomunikasikan pesan CSR pada komunitas nelayan di Perairan Panjang, Jepara, Jawa Tengah. Penelitian ini menjawab bagaiamana komunikasi CSR diterapkan melalui komponen strategi komunikasi yaitu mengenali sasaran, pemilihan media, pengkajian tujuan pesan dan peranan komunikator. Penelitian ini menggunakan metode deskripsi kualitatif dengan data primer diperoleh melalui wawancara dan observasi lapangan serta data sekunder melalui kajian pustaka. Subjek penelitian ini adalah asisten manajer CSR PLN UIK Tanjung Jati B selaku pihak yang bertanggung jawab atas kegiatan CSR perusahaan dan ketua komunitas nelayan selaku pihak yang memperoleh bantuan CSR. Penelitian ini menemukan bahwa CSR berhasil dikomunikasikan pada komunitas nelayan dan dianggap menguntungkan nelayan. Penelitian ini juga menemukan adanya hambatan dalam pelaksanaan komunikasi CSR yang berasal dari faktor-faktor sosio-antropologis, semantik dan psikologis.
Molecular evolutionary trends and biosynthesis pathways in the Oribatida revealed by the genome of Archegozetes longisetosus
Authors: Brückner Adrian , Barnett Austen A. , Bhat Prashant , Antoshechkin Igor A. , Kitchen Sheila A.
Published: June 2022

Oribatid mites are a specious order of microarthropods within the Chelicerata, compromising about 11,000 described species. They are ubiquitously distributed across different microhabitats in all terrestrial ecosystems around the world and were among the first animals colonizing terrestrial habitats as decomposers and scavengers. Despite their species richness and ecological importance genomic resources are lacking for oribatids. Here, we present a 143-Mb chromosome-level genome assembly of the clonal, all-female oribatid mite species Archegozetes longisetosus Aoki, a model species used by numerous laboratories for the past 30 years. Comparative genomic and transcriptional analyses revealed patterns of reduced body segmentation and loss of the segmental identity gene abd-A within Acariformes, and unexpected expression of key eye development genes in these eyeless mites across developmental stages. Consistent with their soil dwelling lifestyle, investigation of sensory genes revealed a species-specific expansion of gustatory receptors, and evidence of horizontally transferred genes related to cell wall degradation of plant and fungal matter, both components of Archegozetes’ diet. Oribatid mites are also noted for their biosynthesis capacities and biochemical diversity. Using biochemical and genomic data, we were able to delineate the backbone biosynthesis of monoterpenes, an important class of compounds found in the major exocrine gland system of Oribatida – the oil glands. Given the mite’s strength as an experimental model, the new high-quality resources provided here will serve as the foundation for molecular research in Oribatida and will enable a broader understanding of chelicerate evolution.
Understanding lipase assays in the diagnosis of pancreatitis in veterinary medicine
Authors: Lim Sue Yee , Steiner Jörg M. , Cridge Harry
Published: June 2022

Pancreatitis commonly occurs in humans, dogs, and cats. For both veterinary and human health-care professionals, measurement of serum pancreatic lipase concentration or activity provides useful support for a diagnosis of pancreatitis. In this Currents in One Health manuscript, we will discuss commonly used lipase assays in veterinary medicine, namely catalytic colorimetric and immunological lipase assays. We highlight potential diagnostic pitfalls associated with analytical specificity, assay validation, and sample condition interferences. Catalytic lipase assays may detect extrapancreatic lipases. In addition, we propose a decision tree for interpretation of lipase assays in the context of a clinical patient.
Distributed Cognition and exam preparation in higher education: what sources students use before and during the Covid-19 pandemic
Authors: Di Blas Nicoletta
Published: June 2022

What ‘sources’ of knowledge do higher education students draw on, to prepare for exams? And has the pandemic made any difference? The study presented in this paper addresses these questions, in the belief that gaining awareness of the sources through which students learn is important for the instructional design of the courses and the evaluation methods as well. Framed within the ‘Distributed Cognition’ theory, the study is based on a questionnaire proposed in July 2021 (summer exam session) to all the students of two schools at Politecnico di Milano (the largest technical university in Italy); 5,369 students responded (16.5% of the total). The results show that students normally resort to a wide range of resources (lectures, lecturer’s slides, group work with other students, notes taken by other students, etc.) and that, in the Covid-19 time, recorded lectures and ‘exercises’ (i.e. practical sessions with a teacher assistant) skyrocket in their perception of relevance, overcoming (almost all) other sources. Academies will need to face the challenge of students advocating for keeping this kind of support even after the Covid-19 era, which has the potential of revolutionising the way universities work, leading towards blended forms of education.
Effects of Sodium Bicarbonate Supplementation in Martial Arts
Authors: Dankovic Goran
Published: June 2022

The aim of this systematic review was to evaluate the effects of consuming sodium bicarbonate (NaHCO3) and to gain insight into the nature of any changes in performance following NaHCO3 supplementation among combat sport athletes. The analysis of the results provides compelling evidence in favor of acute or chronic NaHCO3 supplementation as an ergogenic substance which could have an impact on several aspects of performance in judo [23, 31, 32], taekwondo [17, 20], karate [17, 33] [28, 29], wrestling [18, 19], jiu-jitsu [32] and boxing [16].

Acute or chronic NaHCO3 supplementation is effective in the improvement of several variables of physical performance in combat sports during testing and simulated matches. Enhanced performance resulted in the increased capacity of the glycolytic system. However, the positive effects of its use are most often visible following the onset of fatigue. In addition, the use of NaHCO3 is associated with an increased concentration of lactate in the blood. This systematic review provides data relevant for sports professionals and athletes alike regarding the use of NaHCO3 as a supplement, prior or during training and matches.
Instrumen Musik Ekstrakurikular Pianika di SDN 2 Puja Mulia, Kabupaten Bener Meriah
Authors: Fitri Aida , Kurnita Taat , Sakdiyah Sakdiyah
Published: June 2022

Extracurricular is an activity that is carried out outside the hours of learning. Extracurricular aims to hone the talents and interests of students in various fields of science. This study aims to describe the extracurricular activities of musical instruments pianika and any constraints found teachers in extracurricular activities of musical instruments pianika in SDN 2 Puja Mulia Bandar District Bener Meriah Regency. This research approach is qualitative with descriptive type. Data collection techniques with observation, interviews, and documentation. Data analysis with data reduction, data presentation, data verification. This research was conducted in SDN 2 Puja Mulia Bandar District Bener Meriah Regency. Based on research data that the learning process in the extracurricular activities of musical instruments pianika in SDN 2 Puja Mulia Bandar District Bener Meriah Regency conducted in three meetings. At each meeting consists of three stages of the process learning is the initial stage, the core stage and the closing stage. At the first meeting the teacher gives only insight and basic knowledge of music. At the second meeting, the teacher taught about the technique of searching and blowing and gave the material of the song entitled “Cicak-Cicak on The Wall”. At the third meeting, the teacher repeated the song that had been taught and conducted a practical test. This test is done only to see the skills of students in playing a musical instrument pianika. The constraints on extracurricular activities musical instruments pianika there are three constraint factors consisting of factors: (1) Facilities and infrastructure factors, (2)Family Factor, and (3) Student Factor.
Kontribusi Mata Kuliah Kewirausahawan terhadap Minat Berwirausaha Mahasiswa PGSD FKIP USK
Authors: Nurmasyitah Nurmasyitah , Ahadin Ahadin , Affan M Hussin , Herawati Suci
Published: June 2022

On the basis of entrepreneurship, it really helps students to be able to grow an independent attitude after graduating from the world of lectures, where as we know that unemployment is one of the very serious problems in Indonesia, which is still difficult to reduce the unemployment rate, where there is an increase in the number of residents, the field of work is not much. increase. So it is very cool that the interest in entrepreneurship of students can grow well and high because when viewed in general the interest of the Indonesian young generation in entrepreneurship is still relatively low. Seeing this situation, it is very necessary in the education world where in the curriculum there are entrepreneurship courses, where we know that the world of education has a responsibility to increase interest in entrepreneurship of the younger generation. This study aims to determine the contribution of entrepreneurship courses to the interest in entrepreneurship of PGSD FKIP USK students.
Revisão de literatura digital na etapa exploratória da pesquisa
Authors: Bragagnolo Stefania , De Sousa Richard Perassi Luiz
Published: June 2022

O presente artigo, retrata parte dos resultados da etapa exploratória de pesquisa realizada na Biblioteca Digital Brasileira de Teses e Dissertações (BDTD) e nos repositórios Google Acadêmico e SciELO. Na temática deste estudo foi analisada a identidade e o sistema de identificação da região serrana de Santa Catarina, indicando-se a cidade de Lages como centro de confluência cultural e econômica da Serra Catarinense. No atual momento histórico-cultural da localidade e sua região, é coletivamente proposta a reorganização da identidade regional, diante de transformações socioeconômicas. O desígnio desta pesquisa é a busca de conhecimento sobre elementos e aspectos centrais, distintivos e remanescentes da cultura lageana para, simbolicamente, atualizar o posicionamento identitário da região. Inicialmente para as investigações, foram considerados os títulos e as palavras-chave do material, em seguida, ocorreu a leitura de resumos e a apreciação dos textos selecionados. Obteve-se como base a exploração prévia e observação de símbolos gráficos de identificação e comunicação do posicionamento das marcas institucionais e empresariais de Lages. De modo sucinto, são demonstrados os resultados parciais da pesquisa exploratória, sustentando-se a proposição inicial de desencontro entre o acervo simbólico da cultura regional e a comunicação gráfica das marcas institucionais e empresariais da região que, predominantemente, informam o posicionamento universalista.
Políticas públicas
Authors: Colares Mariane De Matos , Kontz Leonardo Betemps
Published: June 2022

O Atendimento Educacional Especializado (AEE) é uma política pública educacional que a partir da Resolução CNE/CEB Nº 2/200, estabelece que os sistemas de ensino devam matricular os alunos com deficiência, transtornos globais de desenvolvimento e altas habilidades/superdotação nas classes comuns de ensino regular ofertado em Salas de Recursos Multifuncionais (SRM), oferecendo conteúdos curriculares diversificados. O objetivo deste estudo é analisar o Atendimento Educacional Especializado (AEE) como processo de inclusão do indivíduo com necessidades especiais que são desenvolvidos nas Salas de Recursos Multifuncionais (SRM), com materiais que se adaptam às necessidades específicas e individuais do aluno. Trata-se de uma pesquisa bibliográfica, com abordagem qualitativa e descritiva quanto aos objetivos, sendo consultado material de referenciais diversificados sobre a temática e legislações pertinentes. Os resultados mostram que o AEE vem avançando, sendo considerado um marco importante para a educação especial, sobretudo por configurar-se em um trabalho individualizado, atendendo o aluno a partir de suas necessidades específicas possibilitando-lhe um desenvolvimento mais eficaz em relação ao processo inclusivo.