bluuebunny/crossref_metadata_2025 huggingface dataset:
A High-continuity and Annotated Tomato Reference Genome
Authors: Su Xiao , Wang Baoan , Geng Xiaolin , Du Yuefan , Yang Qinqin , Liang Bin , Meng Ge , Gao Qiang , Yang Wencai , Zhu Yingfang , Lin Tao
Published: June 2021

Background: Genetic and functional genomics studies require a high-quality genome assembly. Tomato (Solanum lycopersicum), an important horticultural crop, is an ideal model species for the study of fruit development. Results: Here, we assembled an updated reference genome of S. lycopersicum cv. Heinz 1706 that was 799.09 Mb in length, containing 34,384 predicted protein-coding genes and 65.66% repetitive sequences. By comparing the genomes of S. lycopersicum and S. pimpinellifolium LA2093, we found a large number of genomic fragments probably associated with human selection, which may have had crucial roles in the domestication of tomato. We also used a recombinant inbred line (RIL) population to generate a high-density genetic map with high resolution and accuracy. Using these resources, we identified a number of candidate genes that were likely to be related to important agronomic traits in tomato. Conclusion:Our results offer opportunities for understanding the evolution of the tomato genome and will facilitate the study of genetic mechanisms in tomato biology.
The impact of “4+7” volume based drugs procurement on the volume, expenditures, and daily costs of antihypertensive drugs in Shenzhen, China: a interrupted time series analysis
Authors: Yang Ying , Tong Ruiwen , Yin Shicheng , Mao Lining , Xu Luxinyi , Hao Siyu , Mao Zongfu
Published: June 2021

Background: On January 2019, Chinese government implemented the first round of the National Centralized Drug Procurement (NCDP) pilot of 25 drugs in 4 municipalities and 7 sub-provincial cities in mainland China, referred to as “4+7” policy. In the “4+7” policy, 7 antihypertensive drugs were included. This study was conducted to evaluate the impact of “4+7” policy on the use of policy-related antihypertensive drugs. Method: This study applied single-group Interrupted Time Series (ITS) design. We used drug purchasing data from the Centralized Drug Procurement Survey in Shenzhen 2019, covering 24 months from January 2018 to December 2019. Antihypertensive drugs related to “4+7” policy were selected as study samples, including 7 antihypertensive drugs in the “4+7” List and 17 antihypertensive drugs that have an alternative relationship with the “4+7” List drugs in clinical use. Purchase volume, expenditures, and daily costs were selected as outcome variables, and were measured using Defined Daily Doses (DDDs), Chinese Yuan (CNY), and Defined Daily Drug cost (DDDc), respectively. Segmented linear regression analysis was employed to examine the change of outcome variables before and after the policy intervention.
Results: As of December 31, 2019, the completion rate of the agreed purchase volume of the 7 bid-winning antihypertensive drugs reached 173.42% in Shenzhen. After “4+7” policy, the DDDc of bid-winning antihypertensive drugs significantly decreased by 63.79% (-1.30 CNY, 95% CI= -1.43 to -1.18, p<0.001), while the DDDc of non-winning (0.28 CNY, 95% CI= 0.11 to 0.46, p<0.01) and alternative (0.14 CNY, 95% CI= 0.03 to 0.25, p<0.05) antihypertensive drugs increased markedly. The volume of bid-winning antihypertensive drugs significantly increased by 1311.76% (3.12 million DDD, 95% CI= 2.14 to 4.10, p<0.001). The overall costs of the seven “4+7” List antihypertensive drugs significantly declined by 101.34% (-5.96 million CNY, 95% CI= -7.87 to -4.04, p<0.001) after policy intervention, with an absolute reduction of 36.37 million CNY compared with the pre-“4+7” period.
Conclusion: An overall satisfying implementation effect was observed in Shenzhen. A preliminary positive policy effect of price cut and cost-saving was observed in the antihypertensive drug category. However, the DDDc of non-winning and alternative drugs increased after policy intervention, suggesting that the price monitoring and drug use management regarding NCDP policy-related drugs should be strengthened. Keywords: National Centralized Drug Procurement (NCDP); "4+7"; volume-based procurement; antihypertensive drugs; China
Effects of brief sodium fluoride treatment on the growth of early and mature cariogenic biofilms
Authors: Han Ye
Published: June 2021

Although fluoride has been widely used in the prevention of dental caries, the effect of fluoride on the activity of biofilm in different stages of cariogenic biofilm formation is less studied. This study aimed to investigate the antibiofilm activity of sodium fluoride during early and mature Streptococcus mutans (S. mutans) biofilms formation. S. mutans biofilms were formed on saliva-coated hydroxyapatite disks. In the early (0 ~ 46 h) and mature (46 ~ 94 h) biofilm stages, the biofilm was treated with different concentrations of fluoride (250, 500, 1000, 2000 ppm; 5 times in total, 1 min/treatment). Acidogenicity, dry weight, colony-forming units, water-soluble/insoluble extracellular polysaccharides (EPS), and intracellular polysaccharides were analyzed and confocal laser scanning microscopy images were obtained of the two stages of biofilms (early and mature biofilms). To determine the antibiofilm activity of sodium fluoride during the formation of early and mature biofilms, and to evaluate the relationship between different concentrations of sodium fluoride and antibiofilm activity. In the early cariogenic biofilm formation stage, all fluoride concentration test groups (250, 500, 1000, 2000 ppm) significantly inhibited the growth of S. mutans biofilm. The antibiofilm and anti-EPS formation activities of the brief fluoride treatment increased in a concentration-dependent pattern. At the mature biofilm stage, only the 2000 ppm fluoride treatment group significantly inhibited biofilm accumulation, activity, and intracellular/extracellular polysaccharide content compared with the control and other fluoride treatment groups. The antimicrobial activity of fluoride is related to the formation stage of cariogenic biofilm. The early formation stage of cariogenic biofilm is more susceptible to the inhibition of fluorine than the mature stage. The fluoride treatment in the early formation stage of cariogenic biofilm may be an effective means to control the development of cariogenic biofilm and prevent caries.
Predictive markers of transmission in areas with different malaria endemicity in north-eastern Tanzania based on seroprevalence of antibodies against Plasmodium falciparum
Authors: Kaaya Robert Diotrephes , Kajeguka Debora C , Matowo Johnson J , Ndaro Arnold J , Mosha Franklin W , Chilongola Jaffu O , Kavishe Reginald A
Published: June 2021

BackgroundDue to the scale-up of different interventions, Malaria burden declined significantly in many African countries between 2000 and 2015. As a result, some areas have become suitable for malaria elimination, and in such a situation, Due to the insensitivity of most commonly used methods, malaria transmission assessment is difficult. In north-eastern Tanzania, we tested for Plasmodium falciparum exposure by using serological markers.MethodsA cross-sectional survey was conducted in Bondo, Tanga and Hai, Kilimanjaro between June and December 2014. A total of 788 participants were enrolled and screened for malaria and IgG antibodies against PfAMA-1 and PfMSP-119 antigens using Enzyme-Linked Immuno-Sorbent Assay (ELISA). Malaria parasites were detected using polymerase chain reaction (PCR). The Mann–Whitney test was used to compare the Antibody levels between two independent groups (i.e. positive versus negative). The non-parametric Kruskal-Wallis test was used for comparisons between more than two age groups. Pearson's Chi-squared (χ2) test was used to compare proportions.ResultsGenerally, malaria prevalence by PCR in two sites was 20.4% (161), with Bondo having a higher prevalence of 28.1% (n= 154) as compared to Hai 2.9%, (n= 7), χ2=64.64, p<0.01. Anti-PfAMA-1 and anti-PfMSP-119 antibody concentrations were higher in malaria positive than malaria negative individuals, Mann-Whitney U test, p=0.07 and p=0.003 respectively. Antibody response against PfAMA-1 was significantly different between the three age groups (Kruskal-Wallis test, p<0.001).ConclusionPlasmodium falciparum exposure immunological indicators have proven useful for explaining the dynamics of transmission, especially in low transmission environments like Hai.
Occupational exposure of health care workers to blood and body fluids in West Shewa Zone, Oromia, Ethiopia, 2019: A cross-sectional study
Authors: Solomon Tesfaye , Lemessa Dejene
Published: June 2021

Background: Health care workers are at risk of occupational exposure to blood and body fluids even though very few studies were conducted in Ethiopia. Therefore, this study was aimed to investigate the magnitude of exposure to blood and body fluids among health care workers in governmental health facilities in West Shewa Zone, Ethiopia.Materials & Methods: A facility-based cross-sectional study was conducted in June 2018. A total of 381 health care workers were selected by simple random sampling from 31 sampled governmental health facilities using proportional to size allocation. Data were collected through self-administered questionnaires, entered into Epi-info version 7, and analyzed by SPSS version 21. Adjusted Odds Ratio (AOR) with 95% Confidence Interval (CI) computed for variables maintained in the final model of multivariable logistic regression and statistical significance declared at P<0.05.Results: A total of 377 (98.9%) health care workers participated. The study had shown that 233 (61.2%) of health care workers were exposed to blood and body fluids in their lifetime. Previous needle stick injury (AOR=0.30; 95%CI: 0.12-0.75), place of work (AOR=0.42; 95%CI: 0.26-0.68), and work experience (AOR=1.47; 95%CI: 1.13-1.93) were significantly associated factors with exposure to blood and body fluids.Conclusions: Exposures to blood and body fluids during patient care were common among health care workers in the study area. Therefore, health care workers should give due attention to their occupation's safety. Vaccination and in-service training on standard precautions should be provided and monitored for newly recruited health care workers by the health facilities.
High-speed single perceptron for optical neural networks based on microcombs
Authors: Moss David
Published: June 2021

Optical artificial neural networks (ONNs) — analog computing hardware tailored for machine learning [1, 2] — have significant potential for ultra-high computing speed and energy efficiency [3]. We propose a new approach to architectures for ONNs based on integrated Kerr micro-comb sources [4] that is programmable, highly scalable and capable of reaching ultra-high speeds. We experimentally demonstrate the building block of the ONN — a single neuron perceptron — by mapping synapses onto 49 wavelengths of a micro-comb to achieve a high single-unit throughput of 11.9 Giga-FLOPS at 8 bits per FLOP, corresponding to 95.2 Gbps. We test the perceptron on simple standard benchmark datasets — handwritten-digit recognition and cancer-cell detection — achieving over 90% and 85% accuracy, respectively. This performance is a direct result of the record small wavelength spacing (49GHz) for a coherent integrated microcomb source, which results in an unprecedented number of wavelengths for neuromorphic optics. Finally, we propose an approach to scaling the perceptron to a deep learning network using the same single micro-comb device and standard off-the-shelf telecommunications technology, for high-throughput operation involving full matrix multiplication for applications such as real-time massive data processing for unmanned vehicle and aircraft tracking.
State of use of Electronic Data Capture (EDC) tools in randomized controlled trials in India: results from a survey
Authors: Chakraborty Santam , Mallick Indranil , Bhattacharyya Tapesh , S Moses Arunsingh , Achari Rimpa Basu , Chatterjee Sanjoy
Published: June 2021

Introduction

Electronic data capture (EDC) tools can improve data quality gathered in clinical trials and may be more cost-effective than paper forms. However, limited data is available on the adoption of EDC tools in randomized controlled trials (RCT) conducted in India.
Methods

We invited investigators of registered randomized controlled trials in India to an online survey. The questionnaire included questions on the use of EDC (or alternative data capture methods) and features available. An EDC sophistication level (ranging from 1–6) was computed from the responses obtained. Respondents were also asked about barriers to the implementation of EDC in their setting. The EDC adoption rate (EAR) was defined as the proportion of clinical trials where EDC with a sophistication level of 2 or more was used. Multivariable logistic regression was used to identify factors that predicted EDC adoption.
Results

Responses were received for 400 trials, with an EAR of 27.5% (95% confidence intervals : 23.4–32.1%, n = 110). The number of sites influenced EDC adoption (odds ratio : 1.26, 95% CI : 1.12–1.47, p = 0.001) on multivariable analysis. EAR did not increase over time. The key barriers identified for not using an EDC were lack of technical support (170, 63.0%) and software cost (132, 48.9%).
Conclusion

The survey shows a low EAR in randomized trials registered in India. The barriers identified in the survey would need systematic solutions to improve the EAR in the future.
Factors Enabling Social Media: Exploring Knowledge Sharing amid student community for better academic performance
Authors: Hemalatha R. , Lavanya V. , Karthik B.
Published: June 2021

This paper aims to probe how the determinant influences by accessing of social media to share knowledge among the student which enhances their academic performance. The research particularly identifies in this context, the role of various components associated to knowledge sharing, and use of social media among the student’s community. Methodology – This study has adopted a Prevalence study and the data was analysed with structural equation modelling. Findings – Results approximated to adopt social media tools, which depends upon various associated components. Knowledge sharing attitudes among the student community has helped them more to share their knowledge. However, knowledge sharing approach was determined by the usefulness of knowledge. This was insusceptible from the attempt involved to improvise their academic performance. Research limitations/implications – Respondents of the survey, were done with the students from educational institution of India, cluster random sampling was used for the research. This limits the inferences made from the findings. Practicable implications – This study probes useful perceptiveness on executing social media based knowledge management by the student community. Particularly, it highlights the need to draw attention on underpinning factors, which influences knowledge sharing through social media. Originality – The study which disseminates decisive factors related to knowledge sharing with various tools of social media, thereby prompts and tests a more realistic model which may pave way for knowledge management by student community for academic performance.
Effect of potassium fertilizers associated with cold storage on peach (Prunus persica L.) quality
Authors: Barreto Caroline Farias , Ferreira Letícia Vanni , Navroski Renan , Benati Jorge Atílio , Cantillano Rufino Fernando Flores , Vizzotto Marcia , Nava Gilberto , Antunes Luis Eduardo Correa
Published: June 2021

Potassium (K) fertilization may affect peach quality and preservation. This study aimed at evaluating the effect of doses of K on physico-chemical and functional characteristics of ‘Sensação’ peaches in the postharvest period. Mass loss, pulp color, total soluble solids, titratable acidity, pH, pulp and skin firmness, total concentrations of phenolic compounds and carotenoids and antioxidant activity were evaluated in fruits. The experiment was a randomized block design in a 5x3 factorial scheme, five doses of fertilizers (0, 40, 80, 120 and 160 Kg ha-1 K2O) and three storage periods (harvest day, 10 days and 20 days in cold storage at 1±1ºC, followed by a day of simulated commercialization at 20±1ºC). Mass loss, pulp firmness, phenolic compounds, antioxidant activity and carotenoids decreased when fruit underwent cold storage, independent of the dosage of K fertilization. Doses of 40 and 160 kg ha-1 K2O applied to the soil lead to a larger number of phenolic compounds and higher antioxidant activity in fruits at harvest time. After cold storage, fertilization with 160 kg ha-1 K2O exhibited the highest antioxidant activity and the lowest mass loss in fruits. Increase in doses of K strengthened the color of peach pulp
Thermal degradation kinetics and physicochemical analysis of the freeze-dried hibiscus flower extract (Hibiscus sabdariffa)
Authors: Araújo Auryclennedy Calou de , Santos Francislaine Suelia dos , Costa Marylia de Sousa , Araújo Karoline Thays Andrade de , Gomes Josivanda Palmeira , Silva Wilton Pereira da , Queiroz Alexandre José de Melo , Lima Geovani Soares de , Soares Lauriane Almeida dos Anjos , Santiago Ângela Maria
Published: June 2021

The goal of this research was to evaluate the kinetics of thermal degradation of the hibiscus extracts powder at different temperatures and to characterize physicochemically the freeze-dried aqueous extract of the hibiscus flower (Hibiscus sabdariffa) with different concentrations of maltodextrin (0, 5, 10 and 15%). The analyzed parameters were: water content, total soluble solids, titratable acidity, pH, ash, solubility, hygroscopicity, bulk and tapped density, the flowability (Carr index) and cohesiveness (Hausner ratio), lightness (L*) and intensity of red (a*) and yellow (b*). The degradation kinetics was analyzed by the determination of bioactive compounds of flavonoids, anthocyanins and color appearance parameters (lightness, intensity of red and yellow, chroma and hue angle). The increase in maltodextrin concentration resulted in increases of solubility, soluble solids content, pH and color appearance parameters; as the parameters of bulk and tapped density, hygroscopicity, water content, ash and acidity presented decreases as the proportion of additive increased, showing good flowability and low to medium cohesion. Regarding the degradation kinetics, the maltodextrin was effective in the preservation of anthocyanins and flavonoids of the freeze-dried hibiscus flower up to the temperature of 50 °C. Therefore, this work resulted in the preparation of a product derived from the freeze-drying process with and without additives and with preserved sensory attributes of high quality
Influence of application of nitrogen doses on the post-harvest quality of cucumber
Authors: Pereira Adriane Cristina , Perfeito Danielle Godinho de Araújo , Souza Gabriel Pereira de , Arruda Natália , Benett Cleiton Gredson Sabin , Silva Luciana Maria da
Published: June 2021

The conditions of cultivation and the management of fertilization influence the productivity and the post-harvest quality of cucumbers in an expressive way. In this sense, the aim of this study is to evaluate the physical, chemical and sensorial post-harvest quality of cucumbers for canning purposes submitted to different doses of nitrogen fertilization. The experiment was carried out in a greenhouse at the Goiano Federal Institute (IF Goiano), campus Urutaí and After harvest, the material was sent to the food technology laboratory located in the campus. The soil of the area is classified as Red Latosol according he cucumber cultivar used was the Cucumis sativus L. Kybria F1 hybrid, most suitable for the processing of canned foods. The experimental design was randomized blocks and five treatments (nitrogen doses 0, 50, 100, 150 and 200 kg ha-1), and four replications. The physical parameters fruit length and diameter, fruit fresh matter, production per plant, titratable acidity (TA), pH, soluble solids (SS), moisture, ash content, and SS/TA ratio were evaluated. A sensory analysis was performed using acceptance and ordering-preference tests, in addition to an instrumental evaluation of texture. The application of different doses of nitrogen to cucumber in a protected environment influenced the production per plant and the physical-chemical characteristics of the fruits. However, the sensory quality was not affected. The doses 100 and 150 kg ha-1 of nitrogen is recommended for the production of canned cucumber
Cordia americana: Evaluation of in vitro anti-herpes simplex virus activity and in vivo toxicity of leaf extracts
Authors: Costa Gislaine Franco de Moura- , Panizzon Gean Pier , Oliveira Thalita Zago , Costa Marco Antonio , Mello João Carlos Palazzo de , Nakamura Celso Vataru , Kaneshima Edilson Nobuyoshi , Filho Benedito Prado Dias , Nakamura Tania Ueda-
Published: June 2021

Herpes simplex virus (HSV) type 1 and type 2 are responsible for causing infections whose symptoms can vary from subclinical to severe manifestations. Cordia americana is a plant used by traditional communities for the treatment of wounds and diarrhoea, as well as infections like flu and syphilis. Scientific evidence has shown that, among other biological activities, the plant possesses antiviral properties; however, the evaluation of the in vivo toxicity of preparations of this plant is still lacking. This study assessed the in vitro anti-HSV-1 and anti-HSV-2 activity of a crude extract (CE) obtained from the leaves of C. americana, as well as its aqueous (FAq) and ethyl-acetate fractions (FAc). In addition, the in vivo toxicity of the FAq was assessed. The sulforhodamine B method was performed to determine the antiviral activity and the in vivo toxicity was evaluated according to Brazilian federal regulations. The CE, FAq, and FAc demonstrated antiviral activity against HSV-1 in vitro, presenting EC50 values of 7.0±1.4, 1.5±0.35, and 7.5±3.8, respectively. The FAq also had activity against HSV-2 with an EC50 of 11.8±1.02. The toxicological study of FAq in animals showed that it had very low toxicity. No death occurred during acute or subchronic experiments, where up to 5000 mg/kg and 150 mg/kg FAq were tested respectively; and there were no signs of toxicity in the subchronic test. The results of this study, in conjunction with further studies, pave the way for a potential topical treatment for skin and mucosal diseases, such as HSV-1 and HSV-2 infections
Importance of brassinosteroids in activating the antioxidant system and growth in Jatropha curcas L. plants under water deficit
Authors: Oliveira Diego Braga de , Amaro Camila Lariane , Amaro Liana Verônica , Borges Larissa Pacheco , Amorim Victor Alves , Matos Fábio Santos
Published: June 2021

Climatic changes and drought reduced plant growth and development. Brassinosteroids act in maintaining turgor and plant growth, increasing tolerance to water stress. The objective of the present study was to identify the effect of brassinosteroids in reducing stresses caused by water deficit in Jatropha curcas L. plants. The study was carried out in a greenhouse at the State University of Goiás, in a completely randomized block design in a factorial 2 × 5 arrangement (plants submitted to five brassinosteroids concentrations (0, 2, 4, 8, 16 mg L-1) and two levels of daily water supply (50% and 100% evapotranspiration) six replications and the plot consisted of one useful plant. A 10 mL volume of the hormone was applied 30 days after emergence and 20 mL at 60 days after emergence, totaling 30 ml. The water deficit was imposed at 70 days after emergence and the evaluations were made at 100 d after emergence. Under water deficit, production increased of reactive substances that damage membranes and proteins, but brassinosteroids played an important role in mitigating the deleterious effects of water deficit on J. curcas plants by acting as an elicitor in activating photoprotection mechanisms that increased vegetative growth and maintained membrane integrity. The antioxidant and growth machinery activation reached maximum points at the 8 mg L-1 brassinosteroids concentration and even higher concentrations
Physiological and oxidative defense responses of local rice cultivars “Nusa Tenggara Timur-Indonesia” during vegetative drought stress
Authors: Salsinha Yustina Carolina Febrianti , Indradewa Didik , Purwestri Yekti A. , Rachmawati Diah
Published: June 2021

Drought is the main abiotic factor that reduces productivity of crops such as rice in the suboptimum area. This study aimed to identify drought-tolerance of local rice cultivars “Nusa Tenggara Timur-Indonesia” through their oxidative defense mechanism. In this study, 17 local rice cultivars and two control cultivars (Ciherang and Situ Bagendit) were used. Drought was imposed by using three levels of FTSW: FTSW 1 (control), 0.5 (moderate drought), and 0.2 (severe drought) during the vegetative stage. Growth parameters such as plant height, number of tillers, number of leaves, and total dry weight were higher in Boawae 100 Malam, Hare Tora, and Padi Putih Kuatnana than other cultivars. The analysis of relative water content, chlorophyll, carotenoid, and proline content also indicated that the Boawae 100 Malam, Gogo Sikka, and Hare Tora cultivar showed a higher result compared to control and other cultivars. Thess characters tend to correlate with the higher activity of antioxidant enzymes in Boawae 100 Malam and Gogo Sikka, when exposed to severe drought conditions. Based on principal component analysis of the physiological changes and enzymatic antioxidant activity, the Gogo Sikka, Boawae 100 Malam, and Hare Tora cultivars were classified as rice cultivars with higher drought tolerance
Late summer organic tomato production with heat tolerant tomato cultivars
Authors: Hilborn Samantha , Petersen Michael , Pratt Richard C.
Published: June 2021

Field production of organic fresh-market tomatoes in the U.S. Desert Southwest is desired by local producers and consumers. Tomato yield and fruit quality can be seriously impacted by heat stress (HS) and beet curly top virus (BCTV) infection of the main-season crop. We examined delayed planting of HS tolerant cultivars as a strategy for avoiding and mitigating these abiotic and biotic stressors. In 2016, seven putative HS tolerant cultivars, and one considered to be heat susceptible, were transplanted to the field in mid-summer to avoid peak populations of beet leafhopper (Circulifer tenellus), the vector of BCTV. In 2017, seven HS tolerant cultivars, one heat-susceptible, and two hot-set hybrid cultivars were transplanted in mid-summer. Fruit set was above 75% for most entries, including the heat-susceptible checks. Open-pollinated (OP) and hybrid cultivars exhibited a range of yields from 21.3 to 148.6 Mg/ha and fruit quality ratings from poor to excellent. The OP check ‘Super Sioux’ displayed consistently good yield and quality across years. The correlation between fruit set and yield was low (R2 = 0.29) and significant only at the 0.10 level (P<0.09). The incidence of curly top (incited by BCTV infection) was less than 10% in both years, indicating mid-summer planting aided disease avoidance. ‘Flamenco’, the earliest variety, and two later maturing varieties ‘Florida 91’ and ‘Skyway 687’, are recommended for further evaluation. Mid-summer planting of small and medium-fruited tomato cultivars appears to be a viable option for organic fresh-market tomato production for the fall market in the Southwest USA
Interaction between mycorrhizal fungi and Meloidogyne javanica on the growth and essential oil composition of basil (Ocimum basilicum)
Authors: Silva Beatriz De Almeida E , Cruz Rayane Monique Sete Da , Miamoto Angélica , Alberton Odair , Silva Camila Da , Arieira Claudia Regina Dias-
Published: June 2021

Plant-parasitic nematodes and arbuscular mycorrhizal fungi (AMF) have been reported to alter the yield and chemical composition of basil (Ocimum basilicum) essential oil. The aim of this study was to evaluate the effectiveness of AMF to control the root-knot nematode Meloidogyne javanica in basil and to investigate the effects of nematode-AMF interactions on plant growth, phosphorus (P) absorption, and essential oil composition. The experiment was conducted under greenhouse conditions following a completely randomized 3 × 2 factorial (two fungal species and an uninoculated control × inoculated and uninoculated seedlings) arrangement with 10 replicates. Substrates were inoculated with Claroideoglomus etunicatum, Rhizophagus clarus, or no fungi (control) and sown with basil seeds. After 20 days, half of the seedlings were inoculated with 4,000 M. javanica eggs. After 60 days, the vegetative parameters, P absorption, essential oil composition, nematode population density, AMF root-colonization efficiency, and AMF spore density were determined. The presence of AMF increased the basil’s fresh weight and ability to absorb P, while reducing the M. javanica reproduction. In total, 21 compounds were identified in basil essential oil, the concentrations of which varied according to the treatments. The major components were eucalyptol, linalool, eugenol, β-elemene, trans-α-bergamotene, and τ-cadinol. Inoculation with AMF decreased the linalool levels but increased the amount of eucalyptol. Mycorrhizal plants showed increased shoot height, P uptake, and essential oil yield and a decreased nematode population density in their roots
DEVELOPMENT OF NEW SYNTHESIS ROUTES FOR HYDROXYAPATITE NANOPOWDERS PRODUCTION FROM CHICKEN EGGSHELLS
Authors: Lima Ingrid , Fialho Bonifácio , Simão Renata , Nogueira Daniele , Sampaio Fernanda , Xing Yutao , Castro Jose , Fonseca Gláucio , Campos Marcos
Published: June 2021

Hydroxyapatite (HA) nanopowders are attracting interest for surface application to ceramic biomaterials. In this study, we developed innovative and new viable synthesis routes of calcium phosphate nanopowders from the natural calcium carbonate of chicken eggshells. Following the four routes, alternative co-precipitation, vacuum process, brushite, and calcination, we obtained the HA samples, which were then characterized by different methods. The X-ray diffraction /Rietveld method showed the HA phases, monetite and brushite crystallinity with greater symmetry, and nanoscale. Transmission electron microscopy showed the morphology of nanoparticles functionalized nanoparticles smaller than 100 nm in routes A, B and D, and Fourier-transform infrared spectrophotometry and Raman spectroscopy identified the classic chemical groups of calcium phosphates by four routes mainly groups (PO4) 3- and (CO3 -). Scanning electron microscopy analysis revealed a good surface topography to future cell biointeraction in A, B and D routes, and thermogravimetric analysis showed the mass loss profile inherent to each synthesis route with slot at 200 °C. Hence, the eggshell HA and brushite and the specific monetite nanoparticles with different morphology can be prepared from the four new possible and viable routes using different methods.
Spondias purpurea L. Stem Bark Extract: Antioxidant and in vitro Photoprotective Activities
Authors: Rodrigues Francisco Alessandro , Giffony Priscylla , dos Santos Sarah , Guedes Jhonyson , Ribeiro Maria Elenir , de Araújo Tamara , da Silva Larissa , Zocolo Guilherme , Ricardo Nágila
Published: June 2021

Plant phenolic extracts are widely recognized as an important source of natural antioxidant substances and potential compounds for cosmetic formulations. This study aimed to evaluate the chemical profile, photoprotective and antioxidant activities of stem bark extract of Spondias purpurea L. (ciriguela) and its application in photoprotective formulations. Thirty phenolic constituents were annotated by ultra-performance liquid chromatography coupled with an electrospray ionization quadrupole time-of-flight mass spectrometry in mode negative (UPLC‑QTOF-MS2). The stem bark extract antioxidant and chelation potential, expressed in half maximal inhibitory concentration (IC50), showed 6.25 and 352.22 μg mL−1, respectively. The phenolic extract was used as an active ingredient in six sunscreen formulations, with concentrations ranging from 0.2 to 10%. The ultraviolet (UV) protection properties of the formulations were evaluated by sun protection factor (SPF) values obtained in 0.2 mg mL−1 (0.495 to 2.27) and 2.0 mg mL−1 (2.29 to 15.87). The SPF value for the extract (14.37 and 26.16) was high, but there was a reduction in the base formulation. However, these results suggested that the bioactive extracted of stem bark of Spondias purpurea L. has interesting potential to reduce the damage caused by UV radiation and may be utilized as an active ingredient in a sunscreen formulation.
Reconstruction of Sakīnah Family Criteria During the Covid-19 Period
Authors: Yaqub Andi , Iswandi Iswandi , Nur Jabal
Published: June 2021

This article describes the implementation and achievements of the sakīnah family during the Covid-19 period. Both refer to the technical guidelines of the Indonesian Ministry of Religious Affairs in 2011 regarding the criteria for the sakīnah family. This study uses sociological and al-maṣlaḥah approaches. The research location is in Konda District, Konawe Selatan Regency. The researchers obtained data from the Office of Religious Affairs (KUA), sub-district government, village heads, community leaders, and the public. This study found that the criteria for the sakīnah family were irrelevant to apply. The reason is that the expectations of these criteria are too high, especially in the fields of economy and social status. In addition, the KUA officers did not implement the sakīnah family counselling properly. Thus, the criteria for the sakīnah family need to be simplified and adapted to the conditions and characteristics of each region.
The Efforts Of Sharia Micro Financial Institutions In Increasing Community Income (Case Study Of Bank Wakaf Mikro Honai Sejahtera Papua)
Authors: Yeubun Shimah Fauziah , Firdaus Muhammad Anang , Affandy Fachrudin Fiqri
Published: June 2021

AbstractPurpose - This study aims to determine and analyze the effort of the Honai Prosperous Micro Waqf Bank in Papua in increasing community income in Heram District, Jayapura, Papua Province. Micro Waqf Bank is one of the government programs for low-scale communities.Method - This research uses a qualitative method with a case study approach. Primary data are collected from several informants who have related duties and functions such as managers, boarding school leaders, and customers from the Honai Sejahtera Micro Waqf Bank.  While secondary data includes data from documents, literature, and academic studies and research.  The data that has been collected is then processed and analyzed using a field analysis approach from Miles and Huberman.Result - The results of this study indicate that Honai Sejahtera Micro Waqf Bank improve the communities' income in Heram District by providing a loan for business capital using the Qardh. Besides that, the community felt the positive impact of their existence.Implication - Local Governments need to work together with LKMS to empower communities to escape poverty.Originality- This research focuses on increasing people's income through Islamic Microfinance Institution (LKMS) in Papua Province which has never been studied previously.
From a Farmhand to the Head of an Institute: Life of the Historian Otto Augustovich Lidak
Authors:   St. Petersburg State University, Barinov D. A. ,   St. Petersburg Institute of History of Russian Academy of Sciences, Lebedev V. A. ,   European University at St. Petersburg
Published: June 2021

The history of the Bolshevik party figured prominently in the reform of postrevolutionary Soviet science. After the Civil War, many revolutionaries who took accelerated special learning courses subsequently became professors and heads of newly organized academic institutions. Their aim was to prepare new ideologically strong specialists for the country. However, despite their considerable contribution to higher education in the prewar USSR, a significant number of “red professors” became victims of repression in the 1930s. Otto Augustovich Lidak — one of the main Leningrad historians of the Bolshevik party in the 1930s — was a bright representative of this generation. As a Bolshevik in the Civil war, he traveled from Lithuania to the Siberian city of Minusinsk and from Petrograd to Persia. Having all the necessary qualities (social background, revolutionary experience, connections, etc.), O. A. Lidak was able to build a successful academic career within a short period. At various times, he was the head of the Institute of History of the CPSU(b) and the Communist Institute of Journalism. He was also a professor in the Leningrad branch of the Communist Academy, Communist University, Leningrad State University. Finally, he was an active member of the Society of Marxist Historians, the Society of Former Political Prisoners and Exiles, etc. Thus, he was involved in the work of all the major party institutions that prepared “pro-Soviet” cadres. This article considers the milestones of Lidak’s biography and also explores his contribution to the historiography of the Russian Revolution.
Humanitarian Cooperation of Japan and the USSR in the Second Half of the 20th Century
Authors:   Komsomolsk-on-Amur State University, Kiba D. V.
Published: June 2021

The article provides a periodization of humanitarian cooperation between Japan and the USSR. The first stage was activity of the Press Office of the Soviet Union Council for Japan and the Soviet Information Office in the Land of the Rising Sun in 1946–1957. The second stage was the period of active policy of the USSR Embassy, together with the State Committee for Cultural Relations under the USSR Council of Ministers in 1957–1967. The third stage was defined by the activity of Soviet Embassy and Regional Authorities of Japan and the USSR in establishing cultural relations in 1967–1985. The fourth stage was humanitarian cooperation of both countries carried out under terms of the Soviet-Japan cultural agreement signed in 1986. The fourth stage covers the period from 1986 to 1991. The article identifies the main forms of humanitarian cooperation between two countries. The author believes that connections in the sphere of art were dominant. The Japanese public was an active subject of bilateral relations. The author considers the membership of the Soviet-Japan Friendship Movement and its participants (public organizations, Piece Movement, choral and musical collectives, private companies of Japan) and reveals the reasons for the Japanese public’s interest in Soviet culture based on archival documents and materials of the Japanese and Soviet periodicals. The author points out that the regional cooperation between two countries developed significantly and emphasizes the special role of the USSR Far East as a contact region with Japan.
Introduction
Authors:   University of Texas at Austin, Neuberger J.
Published: June 2021

Eisenstein’s Ivan the Terrible is hardly an obscure film, but it has attracted much controversy and many misconceptions. The goal of this book is to re-examine the film in light of everything Eisenstein wrote about it. The introduction to the roundtable establishes the historical, political, cinematic, biographical, and cultural contexts that shape the book’s multi-disciplinary approach to Eisenstein’s work on Ivan the Terrible. The director structured the story of Ivan’s life and reign in an “interrogative mode” in order to raise profound questions about the nature of violence and tyranny and the psychology of political ambition in Russia’s past, in the Stalinist present, and in the history of state power more broadly. Eisenstein conveyed the history and psychology of power and the inner life of the powerful with a profusion of new cinematic methods that represented the evolution of his thinking about montage. “Polyphonic” montage — the weaving together of audio, visual, sensory, emotional, and intellectual voices—was intended to activate and intensify the spectator’s experience of watching a film; to touch, move, and enlighten the audience in an all-encompassing, transformative way. By approaching Eisenstein’s dynamic theories of history, visual perception, and cultural evolution in relation to one another, this study uncovers a decisive piece: Eisenstein didn’t only want to show the tragic depredations of absolute rule or the universality of power hunger, and he didn’t only want to create a moving emotional experience for viewers.
A Productive Trinity
Authors:   “Kinovedcheskie zapiski” Journal, Kleyman N. I.
Published: June 2021

This Thing of Darkness by Joan Neuberger, about S. M. Eisenstein’s film “Ivan the Terrible”, is the result of enormous work by a professional historian, a serious art critic, and an experienced teacher. The most important features of this productive trinity were manifested in it: a deep knowledge of the history of Russia (equally in the 16th and 20th centuries); a subtle understanding of the specifics of art in general and cinema in particular; the ability to clearly and easily present one’s observations, hypotheses, and conclusions; and finally (last but not least), the successful penetration into the creative world of Sergey Eisenstein, a director and theoretician, draftsman and psychologist, connoisseur of classical world culture and courageous experimentalist-modernist, but at the same time an honest person and a politically minded citizen of his own country in the tragic period of its history, that of Stalin’s tyranny. The author was lucky enough to witness the long-term evolution of this work, from earliest experiments to the publication of a fundamental monograph. In the process of researching archival materials and as we penetrated into the film itself, the circle and type of questions changed. The author expresses confidence that from now on, not a single serious specialist in the history of Soviet cinema, not a single biographer or researcher of Eisenstein’s work can do without the wonderful work of Joan Neuberger.
Eisenstein’s Ivan the Terrible and the History of Mentalités
Authors:   University of Kentucky, Petrone K.
Published: June 2021

This essay explores Joan Neuberger’s book This Thing of Darkness (Cornell University Press, 2019) as a work of cultural history. It praises Neuberger’s use of cultural-historical practices such as the history of mentalités and the study of reception to illuminate Sergei Eisenstein’s artistic process and his subjectivity during the creation of Ivan the Terrible. Neuberger’s work also illuminates the mentalités of the Soviet arts establishment seeking to restrain Eisenstein and keep him in line with Soviet cultural norms. Neuberger convincingly argues that Ivan the Terrible is a subversive critique of Stalin and Stalinism and she demonstrates that Eisenstein was able to assimilate to Soviet society while simultaneously criticizing Soviet power. It remains doubtful, however, whether Soviet audiences understood Eisenstein’s cinematically complex critique. One aspect of the film’s context, however, that might be explored even further is the effect of the cataclysm of the Second World War on the making of Ivan the Terrible. Neuberger addresses Eisenstein’s grief at the loss of friends and the immense difficulties of creating a film after being evacuated, but author wonders whether the intense violence of the film reflects, in some way, Eisenstein’s perceptions of the war. The strength of this book is that it operates on so many different levels of analysis, and while the war is not as fully fleshed out as it might be, this fact does not take away from Neuberger’s mastery of Eisenstein’s milieu.
Eisenstein’s Ivan the Terrible, Indeterminacy, and the Hermeneutics of Suspicion
Authors:   University of Pennsylvania, Platt K. M. F.
Published: June 2021

This essay praises Joan Neuberger’s book This Thing of Darkness (Cornell University Press, 2019) as a great accomplishment in cinematic interpretation and a detailed and subtle historical account. It contests Neuberger’s argument that Eisenstein’s Ivan the Terrible films present an unequivocal critique of Stalin and Stalinism by means of a historical analogy with Ivan. Platt argues that the films are intentionally, stubbornly ambivalent in their representation of Ivan, and by extension Stalin. He contends that although this was indeed a subversive movie in the Stalinist USSR, Eisenstein’s films did not offer any finalized conception of the historical role of these figures, and instead should be viewed as works that thematize the impossibility of achieving certainty in historical interpretation. In reading Neuberger’s This Thing of Darkness, one feels the urgency of the author’s efforts to prove that Eisenstein offered an unequivocal, “radical” and “subversive” denunciation of Stalin and the social violence of his era — one that accords with our own rejection of the Stalinist legacy. Author sympathizes with this effort, but it is misguided. Considered in his own social context, one cannot but appreciate Eisenstein’s bravery in articulating a different, but no less subversive position: as seen through the lens of Ivan the Terrible, Stalinist Russia was revealed to be incomplete, charged with contradictions that made it impossible to come to conclusions concerning the meaning of events.
Response to Roundtable Comments
Authors:   University of Texas at Austin, Neuberger J.
Published: June 2021

In her response, Neuberger elaborates and extends a few of her key arguments as discussed by Brandenberger, Kleiman, Petrone, Platt, and Tsivian. She focuses on questions involving Eisenstein’s exceptionality, the general reception of Ivan the Terrible, Stalin’s response to the film and its homoeroticism, and fundamental questions about Eisenstein’s interpretation of Ivan and his reign, its application to the present and to all rulers. She clarifies fundamental questions about Eisenstein’s conception of dialectics, and shows his commitment to dialectics as something more than more than binary conflict. Eisenstein not only saw all phenomena as “unities of opposites”, but contrasted the dialectical contradictory with a unitary definitive, giving us neither a simpler dualism nor a permanent state of contradiction. The categorical doesn’t cancel out the contested (or vice versa): together the categorical and the contested create another level of complexity, making it possible to see Ivan the Terrible as a film that repeatedly poses questions about power, violence, and human perception, and a film that is a radical critique of Stalinism and Soviet ideology. The author underlines, that in This Thing of Darkness she tried to show that the search for “meaning” in Eisenstein (and in my reading of Eisenstein) was no simple path toward a definitive truth, but is something like the way we experience films: seeing, hearing, intuiting, sensing, learning, feeling, wondering, learning a little more, and eventually thinking through what we have seen and experienced in order to make it meaningful for us.