bluuebunny/crossref_metadata_2025 huggingface dataset:
Processo Discursivo, (re)escrita e ensino
Authors: Puccinelli Orlandi Eni de Lourdes
Published: March 2024

Tomamos a questão do ensino de leitura e escrita e propomos pensar o processo discursivo como mediador desse trabalho, introduzindo a noção de versões, de reescrita e de atenção. Assim, procuramos sair da redução do ensino da língua como processo comunicativo e interacional para propor outros modos de trabalhar a linguagem na escola. Modos estes sustentados na afirmação da linguagem em sua materialidade como “ferramenta imperfeita”.
O capitalismo especulativo e os sentidos sobre o trabalhador: um discurso?
Authors: Massmann Débora , Brasil-Massmann Patrícia
Published: March 2024

O presente estudo se inscreve na perspectiva da análise de discurso, tal como proposta por Michel Pêcheux e Eni P. Orlandi. Nele, propomo-nos a analisar as formas de designar o “trabalhador” no discurso capitalista contemporâneo e seus efeitos na organização social. A análise apresentada nos levou a compreender a quem interessa, nas condições de produção atual, a gourmetização das formas de significar o trabalhador e as relações de trabalho.
A insolência nos movimentos do social: sentidos interditados na favela do Jacarezinho
Authors: Benayon Flavio
Published: March 2024

Ancorado na Análise do Discurso de vertente materialista, o presente trabalho analisa a insolência inscrita na instalação de um memorial às vítimas de uma operação policial realizada na favela do Jacarezinho. O memorial do Jacarezinho, após uma semana de sua instalação, foi derrubado e reduzido a cacos pela Polícia Civil, que interditou a ameaça posta pela tensão entre os sentidos reproduzidos pela ordem vigente e o não sentido. A insolência, compreendida como a resistência no social, dialoga com o não sentido, o não-realizado, ameaçando a administração dos sentidos existentes. Ao qualificar a política vigente no Estado do Rio de Janeiro como genocida e racista, o memorial explicita a corriqueira violência criminosa do Aparelho Repressor, denuncia a barbárie praticada regularmente pela polícia e tensiona sentidos em contradição à descartabilidade biológica do corpo negro, morador da favela.
Performance como ato de insubmissão em Ponciá Vicêncio, de Conceição Evaristo
Authors: Paslawski Luana Gabriela , Freire Schiffler Michele
Published: March 2024

O presente artigo busca analisar o romance Ponciá Vicêncio (2017), de Conceição Evaristo, sob a perspectiva do “tempo espiralar” (Martins, 2002) e da performance (Taylor, 2012). Tratando-se de uma categoria que abrange diversas práticas, ressaltamos os seguintes aspectos que podem ser observados na obra de Evaristo: reiteração, enfrentamento, hibridismo, lugar de contradição, ação concreta e potência para transgressão. Esses elementos serão analisados a fim de pensar as articulações estabelecidas pelos personagens, destacando-se Ponciá e Vô Vicêncio, como formas de romper com os caminhos de vida predeterminados pela colonialidade. Nesse sentido, compreendemos a obra enquanto uma narrativa performática e entendemos a performance nesse contexto como um ato de insubmissão.
Sublime suspense: anomalias góticas em “A faixa malhada”, de Doyle
Authors: Matias Marcus , Gomes Júlia
Published: March 2024

No presente trabalho, realizamos uma descrição dos conceitos referentes ao gênero gótico e ao gênero detetivesco, com os quais buscamos fundamentar a análise do conto “A faixa malhada”, de Sir Arthur Conan Doyle, publicado em 1892, a chamada Era de Ouro das produções detetivescas. Assim, o objetivo dessa pesquisa é demonstrar e evidenciar como a atmosfera provocada pelos elementos góticos causam na narrativa detetivesca de Doyle um efeito de estranhamento, enfatizando o uso do intelecto, característico das obras de detetive, ao mesmo tempo em que imprime um ar de incerteza ao conto. Para alcançar os objetivos dessa análise, nos baseamos, como principal referencial teórico, em Bloch (1998), Rossi (2008), Sá (2019), Vinícius (2013) e Murano (2011). Com base em nossas argumentações, é possível concluir que o conto “A faixa malhada”, faz uso de elementos da literatura gótica de maneira expressiva, influenciando, de certa forma, a perspectiva de leitura, devido ao alinhamento estrutural e temático dos gêneros detetivesco e gótico.

Palavras-chave: Narrativa detetivesca. Gótico. Mistério. Doyle
A construção do ethos no anúncio da Empiricus: uma análise de trueview
Authors: Ramos Ghiraldelli Paula , Barbosa Soares Thiago
Published: March 2024

O presente artigo traz, como objetivo, a análise discursiva de um anúncio trueview da Empiricus Research, protagonizado pela funcionária da equipe publicitária da empresa – Bettina Rudolph –, a fins de que se possa verificar os aspectos culturais, sociais e ideológicos que o envolvem, bem como relações estabelecidas a partir das projeções dos sujeitos enunciativos, possibilitando a compreensão dos mecanismos meritocráticos presentes. Como aparato teórico metodológico, considera-se os conceitos de ethos e da cena da enunciação, ambos desenvolvidos pela Análise do Discurso. A justificativa para a pesquisa compreende a grande repercussão do objeto no contexto em que ele se insere, um momento em que o discurso meritocrático toma força; além do fato de o formato trueview ser um forte marcador da contemporaneidade na publicidade – um novo gênero do discurso a ser melhor investigado. Nossa análise observa que os aspectos que compõe o ethos no objeto ocorrem de maneira suprir as necessidades que marcam a tipologia e o gênero do referido discurso, apesar de se desenvolver dentro de uma particularidade cenográfica. Além disso, o ethos do objeto é construído no sentido de enaltecer o discurso meritocrático e promover uma imagem de sucesso.
Why is Pain not Characteristic of Inflammation of the Lung Tissue?
Authors: Igor Klepikov
Published: March 2024

The article presents materials that make it possible to understand the reason for the absence of one of the classic signs of inflammatory processes in patients with acute pneumonia. The peculiarities of the functional significance of the lungs for the body are the reason that in the case of inflammation in the tissues of the organ, nature has provided for the presence of a more important adaptive mechanism instead of pain as a signal sign. Understanding the causes of the absence of pain in pneumonia in the initial period, which is most responsible for timely and effective care for these patients, allows us to look at the pathogenesis of the disease from a new point of view, which is of fundamental importance for the correction and selection of pathogenetic means of care.
Celite Catalysed Alkylation of Alkenes
Authors: Rojas-Oviedo Irma , Cárdenas Jorge , Márquez Carmen , Twyman Lance J.
Published: March 2024

Abstract. In the presence of Celite mono and disubstituted alkenes could be alkylated with benzylic halides at room temperature. In order to form the C-C bond, it was necessary to use activated aromatics with alkenes or propargylic esters.Resumen. En presencia de celita, alquenos mono- y di-sistituidos pueden ser alquilados con halogenuros de bencilo a temperatura ambiente. Para formar el enlace C-C, fue necesario usar compuestosaromáticos activados con alquenos o ésteres propargílicos.
Highly Efficient Inversion of the C-3 Configuration in 1,2-O-Isopropylidenefuranose Derivatives by an Adapted Swern Oxidation/Sodium Borohydride Reduction Protocol in One Pot
Authors: Cruz-Gregorio Silvano , Hernández Luis , Vargas Mónica , Quintero Leticia , Sartillo-Piscil Fernando
Published: March 2024

Abstract. One pot Swern oxidation-sodium borohydride reduction of1,2-O-isopropylidenefuranose derivatives having the D-gluco or Dxyloconfigurations led to the corresponding stereoisomers resulting from the stereoselective inversion of C-3. This method is a simple adaptation to the traditional procedure that consists in quenching the Swern oxidation at -60 ºC with a mixture of H2O/EtOH (1:4), in which NaBH4 is dissolved. Thus, the inversion of the configuration at C-3 of 1,2-O-isopropylidenefuranose derivatives is accomplished in yields up to 98%.Resumen. La reacción de oxidación de Swern-reducción con borohidruro de sodio en un solo paso de los derivados de 1,2-O-isopropilidenofuranosa con configuración D-gluco o D-xilo, producen sus estereoisómeros correspondientes, los cuales provienen de la inversión estereoselectiva del C-3. Este método es una adaptación al procedimiento tradicional de oxidación de Swern, en donde al término de la reacción se adiciona una mezcla de H2O/EtOH (1:4) a -60 ºC, en lacual se disuelve NaBH4. Así, la inversión de la configuración del C-3en los derivados de 1,2-O-isopropylidenofuranosa se logra en rendimientos hasta del 98%.
Advances in Crystal Growth Techniques of Biological Macromolecules
Authors: Mirkin Nurit , Moreno Abel
Published: March 2024

Abstract. The structural knowledge of some biological macromoleculeshelps to understand their mechanisms of working and their role on health sciences, food science and even their effect on the economy. In this work, some recent solutions to crystallogenesis for structuralanalysis (convective transport, counter-diffusion, the challenge of membrane protein crystallization, and high throughput techniques) are described. Finally, investigations on microgravity, crystal growth under magnetic and electric fields, as well as crystal growth in mesophases (lipid membranes) and microfluidics are carefully revised.Resumen. El conocimiento estructural de muchas biomoléculas ayuda a entender sus mecanismos de acción, efectos sobre la salud, la alimentación e inclusive en la economía. En este trabajo se revisan algunas soluciones a problemas de la cristalogénesis biológica, paraestudios estructurales (convección, la contra-difusión, la cristalización en masa y recientemente el reto de cristalizar proteínas de membrana). Finalmente, se revisan en detalle los trabajos hechos en microgravedad, cristalización bajo campos magnéticos o eléctricos, contra-difusión, sistemas de bicapas lipídicas y sistemas de microfluidos.
Ozone Trend Analysis at Pedregal Station in the Metropolitan Area of Mexico City
Authors: Garfias Vázquez Margarita , Audry Sánchez Javier , Garfias y Ayala Francisco Javier
Published: March 2024

Abstract. Pedregal Station is located in a residential area in thesouthwest portion of Mexico City, where the worst ozone episodes are registered. Three models for forecasting ozone are analyzed based on the 19 mean semester maximum values of daily ozone registered at Pedregal Station. The logarithm model seems to fit best the availabledata. Its use suggests that near 10 years have to elapse fom July 2005, before air quality is recovered. Additional control measures are suggested, such as, doubling concentration of MTBE, reducing gasoline Reid Vapor Pressure from 7.5 to 7 psia and increasing efficiency and cover of the public transport system, but reinforcing the presentcontrol policies.Resumen. En la estación de Pedregal, localizada en la zona residencialde la región suroeste de la Ciudad de México, se registran los peores episodios de ozono. Se analizan tres modelos para pronosticar ozono sobre la base de los 19 datos del valor medio semestral de la máxima concentración diaria de ozono registrados en la estación de Pedregal. El modelo logarítmico es el que se ajusta mejor a los datos disponibles. Su uso sugiere que se requieren cerca de 10 años a partir de julio 2005, para recuperar la calidad del aire respecto al ozono. Se sugieren medidas adicionales de control, tales como doblar la concentración de MTBE, reducir la presión de vapor de la gasolina Reid de 7.5 a 7.0 psia e incrementar la eficiencia y cobertura del transporte público, pero reforzando las medidas actuales.
Kinetic Aspects of Soai´s Asymmetric Autocatalysis
Authors: Buhse Thomas
Published: March 2024

Abstract. Recent kinetic studies are discussed that shed light on thereaction mechanism of the autocatalytic addition of diisopropylzinc topyrimidine carbaldehydes (Soai reaction). Soai’s reaction stands for the exclusive example of chirally autocatalytic reaction system inorganic chemistry and has attracted close attention from several viewpoints: as possible account for the origin of biomolecular homochirality, as potential innovation in enantioselective synthesis or as a further remarkable manifestation of nonlinear dynamics in chemical systems. It is indicated that the reaction is driven by enantioselectiveautocatalysis and mutual inhibition as the essential components. Anumerical approach reveals that experimentally observed chiralamplification and mirror-symmetry breaking can be readily reproducedby a comparatively simple kinetic model that considers monomers as the catalytic species.Resumen. Se discuten estudios cinéticos recientes que dan luz sobreel mecanismo de reacción de la adición autocatalítica de diisopropilzincen pirimidilcarbaldehídos (reacción de Soai). La reacción de Soai se mantiene como un ejemplo exclusivo de un sistema de reacciónquiralmente autocatalítico en química orgánica y que ha atraído laatención desde diversos puntos de vista: como una explicación para elorigen de la homoquiralidad biomolecular, como innovación potencialen la síntesis enantioselectiva o como una notable manifestación de la dinámica no lineal en sistemas químicos. Se ha mostrado que lareacción es dirigida por autocatálisis enantioselectiva e inhibiciónmutua como procesos esenciales. Una aproximación numérica revelaque la amplificación quiral observada experimentalmente y elrompimiento de la simetría especular pueden ser reproducidas a partirde un modelo cinético comparativamente simple y que consideramonómeros como las especies catalíticas.
Ab Initio Study and Hydrogen Bonding Calculations of Nitrogen and Carbon Chemical Shifts in Serine-Water Complexes
Authors: Monajjemi Majid , Mollaamin Fatemeh , Karimkeshteh Tahereh
Published: March 2024

Abstract. The hydrogen bonding (HB) effects on the NMR shielding of selected atoms in a few Ser-nH2O complexes have been investigatedwith quantum mechanical calculations of the 15N and 13C tensors. Interaction with water molecules causes important changes in geometryand electronic structure of serine. Chemical shift calculations, geometry optimization and energies have been performed with ab initio method at HF/6-31G* and HF/6-31G** levels with magnetic properties of the gauge-including atomic orbital method. There is evidence that intermolecular effects are important in determining the 15N chemical shifts of free amino acid residue, to assign principal axes of the tensors, and some systematic trends appear from the analysis of the calculated values. Formation of each interaction (in ten orientations) results in a change of the bridging hydrogen’s chemical shifts of N…H bond that indicate the most stabilized compound. The CαH…O bond plays animportant role in the interactions of amino acids residue upon thestructure and function of a protein. This paper represents comparisonbetween theoretical and experimental values of NMR resonances.Calculations at HF/6-31G** level produce results in better agreementwith the experimental data.Resumen. Los efectos de protección que ejercen en RMN los puentesde de hidrógeno (PH) en ciertos átomos del complejo Ser-nH2O fueron investigados mediante cálculos de mecánica cuántica y tensores de 15N y 13C. La interacción con moléculas de agua causa cambios importantes en la geometría y en la estructura electrónica de la serina. Los cálculos de desplazamientos químicos, optimizaciones de la geometría y los cálculos de energía se llevaron a cabo mediante métodos ab-initio a niveles HF/6-31G* y HF/6-31G** con propiedades magnéticas incluyendo el método del orbital atómico. Hay evidencia de que los efectos intermoleculares son importantes en la determinación de los desplazamientos químicos de 15N del residuo libre del aminoácido para la asignación de los ejes principales de los tensores, y se observaron algunas tendencias sistemáticas a partir del análisis de los valores calculados. La formación de cada interacción (en diez orientaciones) resulta en un cambio de los desplazamientos químicos de la unión N…H, lo que indica un compuesto mas estabilizado. La unión CαH…O desempeña un papel importante en la estructura y en la función de una proteína. Este artículo representa una comparación entre los valores teóricos y experimentales de RMN. Los cálculos al nivel HF/6-31G** produce resultados de mayor concordancia con los datos experimentales.
Synthesis of Rhodium (I) Complexes with Mono and Dithiolato Ligands: Application in Catalytic Hydroformylation of Olefins
Authors: Vargas-Malváez Edgar , Pimentel Georgina , Trujillo Gustavo , Martin Erika
Published: March 2024

Abstract. The thiols,1-phenylethanothiol 1 and 2,4-pentanodithiol 2 were synthesised and used to prepare binuclear rhodium species 3, 4 of the type [Rh2(ìμL)n(cod)2] (L = 1, n = 2; L = 2, n = 1; cod = 1,5cyclooctadiene). NMR and FAB+ mass spectrometry data are consistent with a binuclear structure for the species. These complexes, plus PPh3 or diphosphines (dppp, dppb), were used as catalytic precursors for the hydroformylation of styrene under mild conditions. Fairly good activities and regioselectivities were achieved for catalytic system 3/ PPh3.
 
Resumen. Los tioles,1-feniletanotiol 1 and 2,4-pentanoditiol 2 fueronsintetizados y empleados para preparar especies binucleares de rodio 3, 4 de formulación [Rh2(ìμL)n(cod)2] (L = 1, n = 2; L = 2, n = 1; cod = 1,5-ciclooctadieno). Los espectros de RMN y espectrometría de masas FAB+ son consistentes con una estructura binuclear para estas especies. Estos complejos junto con Pö3 o difosfinas (dppp, dppb), fueron usados como precursores catalíticos en la hidroformilación de estireno en condiciones suaves de reacción. Con el sistema catalítico 3/PPh3 se alcanzaron buenas actividades y selectividades.
Synthesis, Characterization and Structural Aspects of Three New Nonsymmetrical Bimetallic Dibutyltin (IV) Derivatives
Authors: Reyes Horacio , Santillán Rosa , Ochoa Ma. Eugenia , Romero Margarita , Farfán Norberto
Published: March 2024

Abstract. Three new nonsymmetric bimetallic diorganotin compounds derived from hexadentate Schiff bases were obtained by reaction of 2,6-dihydroxybenzene-1,3-dicarbaldehyde with R-(-)-phenylglycinol, glycine and 2-amino-5-nitrophenol, in the presence of dibutyltin oxide. The full multinuclear NMR analysis, IR and elemental analyses allowed to establish the structures of all new compounds. In the three cases, the 119Sn chemical shifts are indicative of two different pentacoordinated tin atoms in solution. The molecular structure of compound 4 in the solid state shows two distinct tin atoms with different geometries, one is a distorted trigonal bipyramid with the oxygen atoms in the axial positions and the organic moieties and imine nitrogen in equatorial ones; while the other tin shows distorted octahedral geometry due to Sn(2)-O(4) intermolecular coordination, leading to a dimeric specie, with a Sn-O-Sn-O four-membered ring. The most interesting issue in the solid state is that only one of the tin atoms exhibits intermolecular coordination, in spite of the fact that the atoms are nearly equivalents.
 
Resumen. El presente trabajo describe la síntesis de tres nuevos compuestos diorganoestaño derivados de bases de Schiff hexadentadas, los cuales fueron obtenidos por reacción de 2,6-dihidroxibenceno- 1,3-dicarbaldehido con R-(-)fenilglicinol, glicina y 2-amino-5-nitrofenol, en presencia de óxido de dibutilestaño. La estructura de los nuevos compuestos se estableció por Resonancia Magnética Nuclear Multinuclear, Infrarrojo y Análisis Elemental. Los desplazamientos de RMN de 119Sn de los tres compuestos, en solución, son característicos de átomos de estaño pentacoordinados. La estructura del compuesto 4, en estado sólido, muestra dos átomos de estaño con diferente geometría; uno de ellos de bipirámide trigonal distorsionada, donde los átomos de estaño ocupan posiciones axiales mientras que los sustituyentes orgánicos y el nitrógeno de la imina están en posiciones ecuatoriales; el otro estaño presenta una geometría de octaedro distorsionado debido a la coordinación intermolecular Sn(2)-O(4) que conduce a la formación de una especie dimérica formando un anillo de cuatro miembros. El aspecto más relevante en estado sólido es que sólo uno de los átomos de estaño presenta coordinación intermolecular a pesar de que los átomos son casi equivalentes.
Antifungal Activity of a Protean Extract from Amaranthus hypochondriacus Seeds
Authors: Rivillas-Acevedo Lina , Soriano-García Manuel
Published: March 2024

Abstract. Plants have developed a variety of protection mechanisms which include the synthesis of both, low molecular weight secondary metabolites and macromolecules as proteins and peptides with antimicrobial activity. There are previous reports of antifungal peptides found on the seeds of other Amaranthus species, so it is very probable that these kind of compounds are present in the A. hypochondriacus seeds. This was confirmed by the antifungal activity of a protean extract from A. hypochondricus against such pathogenic fungi as Alternaria alternata, Fusarium solani, Candida albicans, Fusarium oxysporum, Trichoderma sp. and Aspergillus ochraceus. The fungal growth inhibition was evaluated using the “poisoned” agar and the microspectrophotometry tests.
 
Resumen. Las plantas han desarrollado una variedad de mecanismos de protección contra patógenos entre los que se encuentra la síntesis de metabolitos secundarios y macromoléculas como proteínas y péptidos con actividad antimicrobiana. De las semillas de otras especies de Amaranthus se han aislado péptidos antifúngicos, así que es muy probable que también estén presentes en las semillas de A. hypochondriacus. Lo anterior se confirmó con la actividad antifúngica mostrada por un extracto proteínico de A. hypochondricus contra hongos como Alternaria alternata, Fusarium solani, Candida albicans, Fusarium oxysporum, Trichoderma sp. y Aspergillus ochraceus. La inhibición del crecimiento fúngico se evaluó por los métodos de agar “envenenado” y de análisis microespectrofotométrico.
Homology Modeling and Blind Docking Approach Studies of Pig Heart Fumarase
Authors: Trujillo-Ferrara José , Rosales-Hernández Martha Cecilia , Correa-Basurto José
Published: March 2024

Abstract. The fumarase is an enzyme that could be used as target in drug design to treat infections by Helicobacter pylori and Trypanosoma brucei. In the first step, homology modeling was employed to build the 3D structure of pig heart fumarase (FUM P). Then, Q-Site Finder program was used to identify the potential binding sites of FUM P and fumarase of Saccharomyces cerevisiae (FUM Y). Further, molecular docking of arylderivatives substituted at the aromatic ring with an electron withdrawing or donating groups were evaluated on FUM P and on FUM Y to validate the homology model. The homology model of FUM P showed a structure very similar (70.33 % of identity in sequence) to the crystal structure of FUM Y. Some active sites were identified by Q-Site Finder server on FUM P and on FUM Y which could correspond to sites A and B. The docking results showed that some compounds were bonded at the site A on FUM P and FUM Y being those with electron withdrawing groups with more affinity on FUM P, suggesting that electronic effects are the more important ones during the recognition process by FUM P.
 
Resumen. La fumarasa es un enzima que podría ser usada como blanco en el diseño de drogas para el tratamiento de infecciones por Helicobacter pylori y Trypanosoma brucei. En este trabajo, se creó la estructura en tercera dimensión (3D) de la fumarasa de corazón de cerdo (FUM P) usando modelado por homología tomando como templete a la fumarasa de Saccharomyces cerevisiae (FUM Y). Después, se usó el programa Q-Site Finder para identificar los posibles sitios de unión de FUM P y FUM Y. Posteriormente, se efectuaron estudios de acoplamiento molecular de un grupo de derivados aril monosustituidos con grupos electrodonadores y electroatractores, sobre la FUM P y la FUM Y, con el fin de validar el modelo por homología. La estructura en 3D de la FUM P mostró alta semejanza estructural (70.33 %) con la estructura cristalina de la FUM Y. Algunos sitios de unión de FUM P identificados con el programa Q-Site Finder corresponden a los sitios A y B de FUM Y. Los resultados de docking mostraron que algunos compuestos interactúan en el sitio A de FUM P FUM Y, siendo los de mayor afinidad aquellos que tienen electroatractores sobre FUM P, lo que sugiere que los efectos electrónicos son los más importantes durante el proceso de reconocimiento para FUM P.
Mesoporous Silica-Lanthanum: Characterization and Catalytic Activity on NO Reduction
Authors: Díaz-Jiménez Lourdes
Published: March 2024

Abstract. A series of ordered mesoporous silica-lanthanum materials was prepared. The influence of lanthanum into a silica matrix on the structural, textural and acidic properties is described. The mechanical and hydrothermal stability of mesoporous materials were evaluated. The catalytic activity of cobalt catalyst for selective reduction of nitrogen oxide -in the presence of propane- at temperatures between 350 and 550 °C, was tested. A selective reduction of NO by cobaltbased catalyst raised 18 %, at 450 °C.
 
Resumen. Se preparó una serie de materiales mesoporosos de sílicelantano. Se describe la influencia de la adición de lantano en las propiedades texturales, estructurales y ácidas. También se evaluó la estabilidad térmica e hidrotermal de los materiales. Se probó la actividad catalítica de cobalto, sobre uno de los materiales preparados, en la reducción selectiva de monóxido de nitrógeno con propano a temperaturas entre 350 y 550 °C. Se alcanzó una conversión de 18 % de NO a 450 ºC con el catalizador probado.
Theoretical Investigation Non-covalent Interactions of N-(diphenylphosphinothioyl)-2-pyrazinecarboxamide
Authors: Rashidi Masoud , Dorosti Niloufar , Gholipour Alireza
Published: March 2024

Abstract. Phosphine chalcogenides can form reliable and reproducible supramolecular synthons through noncovalent interactions that can be employed for designing high dimensional supramolecular architectures. Here, we systematically study the influence of non-covalent interactions in the fabrication of these synthons and the stability of the crystalline structure of (N2C4H3)C(O)NHP(S)(C6H5)2 (1) through non-covalent interactions (NCI) analysis, molecular Hirshfeld surfaces and the corresponding two-dimensional (2D) fingerprint plots. The theoretical studies were employed to further confirm the presence of these synthons by comparing the stabilization energies of the dimers and monomers. The nature and electronic structure of the phosphor-chalcogenid bond in (N2C4H3)C(O)NHP(E)(OC6H5)2(E = S(1), O(2), and Se (3)) have also been evaluated by QTAIM, NBO, MEP, and HOMO-LUMO energy gaps.
 
Resumen. Los calcogenuros de fosfina pueden formar sintones moleculares confiables y reproducibles por medio de interacciones nocovalentes que se pueden utilizar para diseñar arquitecturas supramoleculares de alta dimensionalidad. En este trabajo estudiamos sistemáticamente la influencia de las interacciones nocovalentes en la preparación de estos sintones y en la estabilidad de la estructura cristalina de N2C4H3)C(O)NHP(S)(C6H5)2 (1), usando el análisis NCI de interacciones nocovalentes, las superficies moleculares de Hirshfeld y sus correspondientes gráficas bidimensionales (2D). Los estudios teóricos se usaron para confirmar la presencia de estos sintones al comparar las energías de estabilización de los dímeros y monómeros. La naturaleza y estructura electrónica del enlace fósforo-calcogenuro en (N2C4H3)C(O)NHP(E)(OC6H5)2(E = S(1), O(2), y Se (3)) también se estudiaron con QTAIM, NBO, MEP y el gap de energía HOMO-LUMO.
Synthesis and NMR characterization of Bile Acid Derivatives Bearing Ugi 4CR-Modified Side Chains
Authors: Vazquez-Chavez Josué , Verdeja-Perdomo Brian A. , Iglesias-Arteaga Martin A.
Published: March 2024

Abstract. The application of the four-component Ugi reaction for the synthesis of five bile acid derivatives bearing modified side chains is described. The unambiguous structural characterization and assignment of the functional 1H NMR signals and all 13C{1H} NMR chemical shifts are presented.
 
Resumen. Se describe la aplicación de la reacción de cuatro componentes de Ugi a la síntesis de cinco derivados de ácidos biliares que portan cadenas laterales modificadas. Se presenta la caracterización estructural inequívoca y la asignación de las señales funcionales de 1H RMN y de todos los desplazamientos químicos de 13C{1H} RMN.
Evaluating the fairness of credit scoring models: A literature review on mortgage accessibility for under-reserved populations
Authors: Taiwo Inumidun Adegoke  , Onyeka Chrisanctus Ofodile  , Nneka Adaobi Ochuba  , Olatunji Akinrinola
Published: March 2024

This literature review critically evaluates the fairness of credit scoring models concerning mortgage accessibility for under-reserved populations. The review scrutinizes a diverse range of scholarly articles, reports, and empirical studies spanning various disciplines, including finance, economics, sociology, and public policy. It examines the methodologies, findings, and limitations of existing research to illuminate the multifaceted dimensions of credit scoring fairness and its implications for mortgage accessibility. Firstly, the review outlines the conceptual framework of credit scoring fairness, emphasizing the importance of equality, transparency, and accountability in credit assessment processes. It explores the evolution of credit scoring models and their impact on mortgage lending practices, particularly for historically marginalized communities such as racial minorities, low-income households, and individuals with limited credit histories. Secondly, the review analyzes the methodologies employed in evaluating the fairness of credit scoring models. It identifies key metrics and statistical techniques used to assess disparities in mortgage approval rates, interest rates, and loan terms across demographic groups. Thirdly, the review synthesizes empirical evidence on the extent and persistence of disparities in mortgage accessibility for under-reserved populations. It highlights systemic barriers, including discriminatory lending practices, redlining, and institutionalized biases embedded within credit scoring models. Fourthly, the review discusses the implications of credit scoring fairness for financial inclusion, social equity, and economic mobility. It underscores the need for innovative policy interventions, industry best practices, and consumer education initiatives to address systemic inequities in mortgage lending and promote inclusive homeownership opportunities for under-reserved, Finally, this literature review offers a comprehensive overview of the fairness of credit scoring models in the context of mortgage accessibility for under-reserved populations. By synthesizing empirical evidence, theoretical frameworks, and policy implications, it contributes to a deeper understanding of the challenges and opportunities in promoting equitable access to homeownership and financial security for all.
Enhancing audience engagement through ai-powered social media automation
Authors: Ashok Manoharan
Published: March 2024

Enhancing Audience Engagement using AI-Powered Social Media Automation is a significant part of modern marketing techniques. This research addresses the application of artificial intelligence (AI) to automate social media interactions to boost audience engagement. The study dives into numerous AI approaches and algorithms applied in social media automation and assesses their success in enhancing audience participation, brand exposure, and customer happiness. The research explores the influence of AI-powered automation on multiple social media platforms. It assesses its potential to boost audience engagement metrics such as likes, shares, comments, and click-through rates. The study identifies critical elements driving audience engagement through detailed analysis and modeling and suggests techniques for enhancing AI-powered social media automation processes. The results add to excellent knowledge of how AI technology may be exploited to generate more meaningful interactions with online audiences, eventually boosting corporate development and consumer loyalty in the digital age.
Study of environmental risk levels due to organic solid waste on the Andrés Avelino Cáceres Platform in the District of José Luis Bustamante y Rivero-Arequipa
Authors: Matilde Yupanqui Mendoza  , Virginia Luisa Pérez Murillo  , Kely Olave Baez
Published: March 2024

The Nueva Esperanza Market located on the Andrés Avelino Cáceres Platform is a high traffic area, as it is the largest market in Arequipa. The levels of environmental risk due to solid organic waste were studied in the areas of vegetables, fruits, tubers and around the market in these areas. The methodology consisted of three field trips for data collection, carried out through observation and recording of records of environmental impact factors, which allowed the formulation of environmental risk matrices in the natural environment and in the human environment. According to the results obtained through the use of the various tables and matrices, in the assessment of environmental impacts a value of – 15 was obtained, which indicates an impact that is severe and reversible, if corrective and improvement measures are taken immediately. keep going. In estimating the severity of the consequences of an environmental risk in the natural environment, the vegetable area has the highest risk severity with a value of 16 and a total score of 4, followed by the fruit area and the market surroundings. Regarding the severity of the consequences of an environmental risk in the human environment, the area of vegetables and fruits has a value of 18 and a total score of 5. Concluding that the risks in the identified scenarios of vegetables and fruits have a severity of high risk, followed by the tuber area and surroundings of the market.
A new dawn: The next frontier in AI-driven sleep enhancement through gradual awakening
Authors: Vadim Fîntînari  , Zaki Milhem  , Nicolae Goga
Published: March 2024

Background: Given the prevalence of sleep issues, their impact on overall health and the potential of gradual awakening in mitigating part of the negative effects, innovative solutions can be leveraged to facilitate this awakening process. Objectives: The current study aims to present in detail and validate a novel system that utilizes advanced AI algorithms for sleep tracking, sleep stage prediction, and a "smart alarm" component for optimal gradual awakening. Methods: A clinical trial was conducted to assess the system's effectiveness, namely its influence on several key daily aspects. Participants wearing consumer wearable devices in their sleep were required to self-assess their quality of life, sleep quality and perception of their own waking process through several questionnaires. Results: The integrated system is developed and works as intended. The clinical study findings demonstrate statistically significant benefits in quality of life, sleep quality, user satisfaction with the waking process and mental status upon awakening. On average, an increase in WHOQOL-BREF score from 88.44 to 94.75, a decrease in Sleep Quality Scale scores from 65.66 to 58.19 and in awakening scores from 10.81 to 8.95 (the latter two scores decrease as outcome improves) were observed. Conclusion: Our system shows promise for enhancing individual well-being and productivity by detecting the optimal sleep stage for awakening and providing a more natural waking experience, indicating a valuable direction for future sleep health technologies. Research should be directed at expanding the search for more potential uses, optimizing algorithms and improving user experience.
PROSES BERPIKIR KREATIF GURU DALAM MENDESAIN TUGAS MATEMATIK
Authors: Alam Syamsu , Taufiq Taufiq , Ramadhani Widya Putri
Published: March 2024

Students have different backgrounds and abilities. Therefore, teachers must be good at choosing and giving math assignments to their students. The purpose of this study was to reveal the creative thinking process of teachers in designing math assignments. The participants in this study were elementary school teachers in Pangkep district, South Sulawesi based on their functional position (focusing on intermediate teachers). This study used a qualitative approach, with data collection methods using task-based interviews. From the results obtained, we found the subject's thinking process followed the sequence of stages of synthesizing ideas, constructing ideas, planning the application of ideas, and applying ideas.
ANALISIS PENALARAN MATEMATIS SISWA PADA MATERI FUNGSI EKSPONEN
Authors: Marlan Marlan , Ratumanan Tanwey Gerson , Palinussa Anderson Leonardo
Published: March 2024

This research was motivated by the difficulties of SMA Negeri 5 Maluku Tengah students in understanding exponential function material. One of the abilities that must be possessed to understand mathematics is mathematical reasoning. This research uses qualitative descriptive research methods. The subjects in this research were 3 students selected from 34 students based on their odd semester final exam scores for the 2021/2022 academic year in the high, medium and low categories. The instruments used were test question and interview guidelines. The test instrument consist of 4 essay questions which are prepared based on mathematical reasoning indicators and have been validated. The research result show that overall student mathematics is in the medium category with a percentage 50%. All three subjects can fulfill all rhe specified mathematical reasoning indicators. The subject’s ability to carry out mathematical reasoning is determined by the subject’s initial knowledge and subject’s ability to use his knowledge in developing appropriate solution strategies
PERSEPSI PEDAGANG TENTANG KEBERSIHAN DAN SANITASI PASAR PURING KOTA PONTIANAK TAHUN 2023
Authors: Mutia Mutia , Anwar Taufik , Salbiah Salbiah
Published: March 2024

Persepsi pedagang mengenai sampah sering kali tidak ditanggapi dengan baik oleh pedagang di Pasar puring sehingga menimbulkan penumpukan sampah yang berlebihan dan bisa berdampak terhadap kebersihan dan sanitasi lingkungan.  Penelitian ini bertujuan untuk mendeskripsikan persepsi pedagang tentang kebersihan dan sanitasi, dan menganalisis hubungan antara persepsi pedagang terhadap kebersihan dan sanitasi pasar puring Kota Pontianak. Metode penelitian ini merupakan penelitian kuantitatif dengan pendekatan desain cross sectional. Sampel yang digunakan 63 responden dengan Teknik Acak Sederhana (simple random sampling). Teknik untuk menganalisis data menggunakan uji chi square. Lokasi penelitian dilakukan di Pasar Puring, Siantan Tengah, Kecamatan Pontianak Utara, Kalimantan Barat. Hasil penelitian ini menggunakan uji chi square diperoleh hasil nilai sig/p value 0,03 < α 0,05 bahwa ada hubungan persepsi pedagang tentang kebersihan dan sanitasi pasar puring. Sebagian besar pedagang pasar puring mempunyai persepsi yang kurang baik dan kurang bersih tentang kebersihan dan sanitasi pasar puring. Kesimpulan hasil penelitian ini ada hubungan persepsi pedagang tentang kebersihan dan sanitasi pasar puring kota pontianak tahun 2023.
GAMBARAN EVALUASI KEGIATAN UPAYA PENINGKATAN ANGKA BEBAS JENTIK (ABJ) DI WILAYAH KERJA PUSKESMAS NANGA PINOH 2022
Authors: Sahrunika Cahyani Rahmanisa  , Fathmawati Fathmawati , MaIik Saepudin
Published: March 2024

Angka bebas jentik di  Penyakit DBD masih menjadi masalah kesehatan dan ancaman serius di seluruh wilayah di Indonesia di tahun 2022, jumlah kasus  Dengue di Indonesia sampai ke 2022 dilaporkan 45.387 kasus. Pada Provinsi Kalimantan Barat jumlah kasus warga terjangkit demam berdarah dangue (DBD) meningkat drastis. Sejak Januari hingga Oktober 2022, setidaknya sudah ada 985 kasus. Tujuan dalam penelitian ini, yaitu mendeskripsikan gambaran evaluasi kegiatan upaya peningkatan Angka Bebas Jentik (ABJ) di wilayah kerja Puskesmas Nanga Pinoh 2022. Metode penelitian yang digunakan wawancara pelaksana program hygiene sanitasi di puskesmas Nanga Pinoh. Hasil dari penelitian ini menunjukan bahwa dana kegiatan kurang mencukupi untuk melaksanakan kegiatan peningkatan ABJ di wilayah kerja menjadi penghambat dalam kegiatan peningkatan ABJ, dalam proses kegiatan peningkatan ABJ pelaporan telah dilakukan dengan baik, target peningkatan ABJ belum mencapai target yang telah di tetapkan yaitu 95%.
GAMBARAN PENGETAHUAN, SIKAP DAN PERILAKU MASYARAKAT DALAM PENGELOLAAN SAMPAH RUMAH TANGGA DI RW 13 WILAYAH KERJA PUSKESMAS TANJUNG HULU
Authors: Syarifah Elsa Pitri  , Salbiah Kastari  , Asmadi Asmadi
Published: March 2024

Sampah merupakan salah satu penyebab tidak seimbangnya lingkungan hidup, yang umumnya terdiri dari komposisi sisa makanan, plastik, logam, kaca dan lain-lain. Tujuan penelitian ini adalah untuk mengetahui gambaran pengetahuan, sikap dan perilaku masyarakat dalam pengelolaan sampah rumah tangga di RW 13 wilayah kerja puskesmas Tanjung Hulu. Jenis penelitian ini adalah deskriptif observasional dengan menggambarkan pengetahuan, sikap dan perilaku masyarakat dalam pengelolaan sampah rumah tangga di RW 13 wilayah kerja Puskesmas Tanjung Hulu. Jumlah sampel sebanyak 72 ibu rumah tangga. Data perilaku responden diperoleh dari observasi di lapangan. Hasil penelitian menunjukkan bahwa responden rumah tangga di RW 13 wilayah kerja puskesmas Tanjung Hulu pengetahuan baik 73%, cukup 16% dan kurang 9%. Sikap responden dalam pengelolaan sampah rumah tangga adalah baik 100%. Sedangkan perilaku responden dalam pengelolaan sampah rumah tangga adalah cukup 4% dan kurang 96%. Kesimpulan dalam penelitian ini adalah bahwa pengetahuan dan sikap masyarakat dalam pengelolaan sampah rumah tangga di RW 13 wilayah kerja puskesmas Tanjung Hulu adalah baik. Sedangkan perilaku warga dalam pengelolaan sampah rumah tangga adalah kurang.
HUBUNGAN PENGETAHUAN TENTANG PROSEDUR OPERASI DENGAN TINGKAT KECEMASAN PADA PASIEN PRE OPERASI LAPARATOMI RSUD dr. ABDUL AZIS SINGKAWANG TAHUN 2021
Authors: Roelanda Alvi , Limson Leonatus , Nurbani Nurbani
Published: March 2024

Laparatomi merupakan jenis operasi bedah mayor yang dilakukan di daerah abdomen, Pembedahan dilakukan dengan penyayatan pada lapisan-lapisan dinding abomen untuk mendapatkan bagian organ abdomen yang mengalami masalah seperti syok hemoragi, perforasi, kanker, dan obstruksi. Kecemasan pasien pre operatif dapat disebabkan oleh berbagai faktor, salah satunya adalah faktor pengetahuan dalam mengaplikasikan pencegahan kecemasan pada pasien pre operatif. Tujuan penelitian ini adalah untuk mengetahui hubungan pengetahuan tentang prosedur operasi dengan kecemasan pada pasien pre operasi laparatomi RSUD dr. Abdul Azis Singkawang tahun 2019. Metode penelitian yang digunakan adalah dengan desain Cross sectional. Teknik pengambilan sampel menggunakan kuesioner pengetahuan yang berisi 15 item pertanyaan dan kuesioner kecemasan berisi 14 pertanyaan. Jumlah sampel dalam penelitian sebanyak 34 responden dari pasien pre operasi laparatomi. Analisa data menggunakan chi square. Hasil dari penelitian dengan hubungan pengetahuan tentang prosedur operasi dengan kecemasan pasien pre operasi laparatomi menghasilkan P value sebesar 0,000 dengan nilai signifikansi sebesar 0,05. Jadi nilai P < 0,05 ( Ha diterima). Kesimpulan dalam penelitian ini yaitu terdapat hubungan pengetahuan tentang prosedur operasi dengan kecemasan pada pasien pre operasi laparatomi di bangsal bedah RSUD dr. Abdul Azis Singkawang tahun 2019. Bagi profesi keperawatan, bagi institusi rumah sakit, bagi peneliti selanjutnya dan bagi responden semoga peneliti yang dilakukan ini dapat bermanfaat dan dapat meningkatkan pelayanan kesehatan menjadi lebih baik untuk ke depannya.
DETERMINAN FAKTOR YANG BERHUBUNGAN DENGAN MANAJEMEN DIRI PASIEN HIPERTENSI
Authors: Baedlawi Azhari , Ardiansyah Fakrul , Hustra Tika Desvicasari , Prasetyo Restu Dwi
Published: March 2024

Pendahuluan. Hipertensi atau biasa disebut dengan darah tinggi kian menunjukkan peningkatan prevalensi. Data riskesdas menunjukkan adanya peningkatan yang signifikan. Diprediksi tahun 2025 sekitar 29% populasi dunia menderita hipertensi. Sepertiga total populasi Indonesia menderita hipertensi. Tujuan. Penelitian ini bertujuan untuk menganalisis faktor yang berhubungan dengan manajemen diri penderita hipertensi. Metode. Penelitian ini adalah penelitian observasional. Sampel berjumlah 149 responden. Penderita hipertensi yang memiliki keparahan berat tidak dilibatkan dalam penelitian ini. Penelitian ini menggunakan kuesioner data demografi dan kuesioner manajemen diri yang dimodifikasi oleh peneliti. Hasil. Sebagian besar responden berusia 47-59 tahun, jenis kelamin laki-laki, tingkat pendidikan SMA, pekerjaan ibu rumah tangga, penghasilan dibawah UMR, lama mengidap hipertensi > 5 tahun, memiliki Riwayat hipertensi, belum pernah mendapatkan edukasi terkait hipertensi, tidak memiliki penyakit penyerta, mengkonsumsi obat hipertensi, tidak mengkonsumsi obat herbal, dan memiliki hipertensi tidak terkontrol. Terdapat hubungan antara Riwayat pekerjaan dan Riwayat hipertensi dikeluarga dengan manajemen perawatan diri hipertensi (p = 0,01 dan p = 0,03). Tidak terdapat hubungan antara usia, jenis kelamin, Tingkat pendidikan, penghasilan, lama mengidap hipertensi, edukasi tentang hipertensi, riwayat penyakit penyerta, konsumsi obat hipertensi, konsum herbal, dan status hipertensi dengan manajemen diri penderita hipertensi (p > 0,05). Kesimpulan. Pasien hipertensi perlu meningkatkan manajemen perawatan diri utamanya pengidap hipertensi yang memiliki riwayat hipertensi di keluarga.
PENGARUH VIDEO KESEHATAN REPRODUKSI TERHADAP PENGETAHUAN REMAJA PUTRI TENTANG BAHAYA KEHAMILAN USIA DINI DI SMAN 2 SELAKAU
Authors: Haulia Haulia , Marsia Marsia , Rangkuti FSRH Winnellia
Published: March 2024

Kesehatan reproduksi remaja adalah suatu kondisi kesehatan yang memuat tentang masalah kesehatan organ reproduksi yang persiapannya dimulai dari masa remaja ditandai dengan menstruasi pertama untuk gadis remaja.Masa remaja merupakan masa transisi antara anak-anak dan orang dewasa, mulai dari usia sekolah menuju usia kerja, serta memasuki usia reproduksi. Kehamilan remaja merupakan kehamilan yang terjadi pada wanita yang berusia 14-20 tahun baik pada remaja yang sudah menikah maupun yang belum menikah. Kehamilan remaja memberikan risiko yang sangat tinggi terhadap kematian ibu dan bayi, hal ini dikarenakan kehamilan remaja bisa menyebabkan terjadinya perdarahan pada saat hamil yang berisiko terhadap kematian ibu. Oleh karena itu, untuk menghindari risiko yang berbahaya bagi remaja, diperlukan adanya pencerahan, perhatian, dan perlindungan yang khusus, agar remaja memahami cara memproteksi diri dari berbagai bahaya yang dapat merugikan masa depannya melalui video kesehatan reproduksi.  Penelitian ini menggunakan desain penelitian Quasy Experiment, yaitu penelitian yang menguji coba suatu intervensi pada suatu objek dengan atau tanpa kelompok pembanding namun tidak dilakukan randominasi untuk memasukan subjek ke dalam kelompok perlakuan atau kontrol. Desain eksperimental dalam penelitian ini menggunakan rancangan pre test and post test without control group design dimana pada desain ini, peneliti hanya melakukan intevensi pada satukelompok tanpa kelompok pembanding. Instrumen penelitian menggunakan kuesioner dengan mengambil data secara langsung. Hasil penelitian sebelum diberikan media video kesehatan reproduksi dengan nilai rata-rata (mean) sebesar 70.33% dengan klasifikasi pengetahuan paling banyak kategori cukup yaitu sebanyak 31 responden (52.5%). Adapun hasil penelitian setelah diberikan media video kesehatan reproduksi dengan nilai rata-rata (mean) sebesar 81.49% dengan klasifikasi pengetahuan paling banyak dengan kategori baik yaitu sebanyak 43 responden (72.9%).Terdapat perbedaan pengetahuan remaja sebelum dan sesudah diberikan pendidikan kesehatan melalui video tentang bahaya kehamilan usia dini dengan p value (0,000) pada uji wilcoxon.  Simpulan penelitian ini adalah pengetahuan remaja sesudah diberikan pendidikan kesehatan melalui video lebih tinggi dibandingkan sebelum diberikan pendidikan kesehatan melalui video.