bluuebunny/crossref_metadata_2025 huggingface dataset:
Ellen Amman (1870–1932)
Authors: Berger Manfred
Published: November 2023

Ellen Ammann hat die inhaltliche und organisatorische Entwicklung der Wohlfahrtspflege wegweisend beeinflusst. Sie rief mehrere sozial-caritative Einrichtungen ins Leben und legte den Grundstein für die Professionalisierung der vor allem von Frauen geleisteten Sozialen Arbeit.
Zum Verhältnis von Unterlassungsanspruch und Rückrufanspruch
Authors: Klinger Cornelius
Published: November 2023

It is generally accepted that the injured party must act to comply with the injunction if inaction would be tantamount to a continuation of the infringing act. It is controversial whether the injured party is also obliged to cease acts that affect the sphere of independent third parties. The author examines whether an extension of the injunction to a recall obligation is necessary to ensure effective legal protection from the creditor's point of view. Furthermore, it is examined whether the extension of the injunctive relief is accompanied by an increase in efficiency. In addition, the specific recall obligation of the injunction debtor in different distribution constellations is determined.
„Ex castro suo monasterium fecit“
Authors: Haupt Simon
Published: November 2023

The art-historical work provides an in-depth insight into the phenomenon of castles converted into monasteries, which was widespread throughout the Western world during the Middle Ages. The author, who is regularly involved in excavations, uses his knowledge of castle research to be able to adequately interpret the corresponding irregularities in the topography and the overall layout of a monastic complex - a methodological approach that makes perfect sense according to the Berlin state archaeologist, Prof. Dr Matthias Wemhoff. The work is a useful basis for future research into castles and monasteries.
Trans-Frontier Socio-Cultural Interactions and Learning for Epidemic Preparedness and Control
Authors: Chirawurah Dennis , Apanga Stephen , Santuah Niagia
Published: November 2023

West Africa’s extensive migratory activities and unregulated cross-border community interactions between countries pose challenges to epidemic preparedness and control. Understanding of the nature of these activities and interactions is therefore necessary for epidemic preparedness planning and response. We used a qualitative cross-sectional study to conduct focused group discussions and key informant interviews in contiguous border communities in Ghana and Burkina Faso to assess if and how cross border interactions compromise or facilitate management of public health emergencies. Knowledge and perception of the severity of epidemics in Ghana and Burkina Faso is high, and existing local networks and institutions have the capacity to effectively respond to public health emergencies when properly mobilized. Managing cross-border community interactions and interrelationships and respectful cross-cultural dialog among the multiplicity of stakeholders within and between the two countries is sine qua non for constructing a robust and responsive architecture for effective epidemic preparedness and control.
A Hybrid Intelligent Approach to Breast Cancer Diagnosis and Treatment Using Grey Wolf Optimization Algorithm
Authors: Dehghan Mohammad Jafar , Azizi Amirabbas
Published: November 2023

Background: Breast cancer is the second leading cause of death in women. The advent of machine learning (ML) has opened up a world of possibilities for the discovery and formulation of drugs. It is an exciting development that could revolutionize the pharmaceutical industry. By leveraging ML algorithms, researchers can now identify disease-related targets with greater accuracy. Additionally, ML techniques can be used to predict the toxicity and pharmacokinetics of potential drug candidates. Objectives: The main purpose of ML techniques, such as feature selection (FS) and classification, is to develop a learning model based on datasets. Methods: This paper proposed a hybrid intelligent approach using a Binary Grey Wolf Optimization Algorithm and a Self-Organizing Fuzzy Logic Classifier (BGWO-SOF) for breast cancer diagnosis. The proposed FS approach can not only reduce the complexity of feature space but can also avoid overfitting and improve the learning process. The performance of this proposed approach was evaluated on the 10-fold cross-validation technique and the Wisconsin Diagnostic Breast Cancer dataset. Although the performance of breast cancer detection is highly dependent on classification accuracy, most good classification methods have an essential flaw in that they simply seek to maximize the accuracy of classification while ignoring the costs of misclassification among various categories. This is even more important in classification problems when the initial set of features is large. With such a large number of features, it is of special interest to search for a dependency between an optimal number of selected features and the accuracy of the classification model. Results: In experiments, standard performance evaluation metrics, including accuracy, F-measure, precision, sensitivity, and specificity, were performed. The evaluation results demonstrated that the BGWO-SOF approach achieves 99.70% accuracy and 99.66% F-measure, which outperforms other state-of-the-art methods. Conclusions: During the comparison of the results, it was observed that the proposed approach gives better or more competitive results than other state-of-the-art methods. By leveraging the power of ML algorithms and artificial intelligence (AI) and the findings of the current study, we can optimize the selection of natural pharmaceutical products for the treatment of breast cancer and maximize their efficacy.
SEISMOLOGICAL, GEOTECHNICAL ANDSTRUCTURAL ASPECTS OF THE 2023 KAHRAMANMARASH, TURKEY EARTHQUAKE SEQUENCE
Authors:   Turkey, Erberik Murat , Askan A. , Kockar M , Altindal Altug , Ozsimsir A. , Sahin G
Published: November 2023

Abstract. On 6 February 2023, Turkiye was hit by a sequence of very strong and destructiveearthquakes that affected 11 populated cities close to the ruptured fault line. The damage was very extensive in the region so that it was even to understand the orderof magnitude of the huge devastation and loss caused by this earthquake sequence.Many national and international research teams have been in the affected areas fromthe first day on, trying to make field observations from all aspects and get the per- ishable field data to use for the purpose of seismic loss mitigation for future poten-tial events. The observations reveal the fact that it will take a long time for the coun-try to recover from the adverse effects of this event, but we should also start the takemeasures immediately to mitigate the potential losses from future earthquakes.
Economic development of independent Azerbaijan: Ilham Aliyev’s modelAbstract
Authors:   Azerbaijan University of Architecture and Construction, Mamedov M.
Published: November 2023

In the article, within 20 years from 2023, as a result of the implementation of the measures envisaged in the state programs, development strategies and concepts prepared by the relevant decrees of President Ilham Aliyev, the processes of ensuring continuous and sustainable development of the country s economy, dynamic development of all areas of the economy, and effective integration into the world economic system , the directions of restoration and reconstruction of the infrastructure of the areas of the economy of the territories freed from occupation and the reintegration of the economy ofthese territoriesinto the country s economy and the achieved successes were discussed.
Influence of casting method and process optimization on pricing
Authors:   Azerbaijan State Oil and Industry University, Aliyev E.
Published: November 2023

The article provides for a comprehensive study of price systems and methods for their justification for foundry products, as well as the development of methodological principles for restructuring pricing in this industry as an effective economic tool to improve the efficiency and quality of production. Using the theory of fuzzy sets, a scheme of the technological process has been developed, taking into account the factors affecting the cost of casting. An example of the formation of a competence matrix based on the requirements of fuzzy logic is shown, which defines a system of logical statements. An expert evaluation of combinations of values of input variables has been carried out.
Classification of methods of cost approach for assessment of business cost
Authors:   Azerbaijan University of Architecture and Construction, Mammadov I. , Alekperov S. ,   VTB Bank, specialist
Published: November 2023

The article discusses methods for assessing the value of a business, their classification, the right to use methods depending on the specific conditions for assessing a business
Improvıng mechanısms for stımulatıng the development of small and medıum busıness entıtıes
Authors:   Azerbaijan University of Architecture and Construction, Yusifov E. , Hasanova G. ,   Azerbaijan University of Architecture and Construction, Hasanov E. ,   Baku Eurasian University
Published: November 2023

The article discusses the role of small and medium-sized business entities in the economic system and the state s participation in their development. The basics of supporting and promoting the activities of small and medium business entities are studied depending on the functions performed by them. The components of the infrastructure for the development of the relevant economic subjects are defined and recommendations are made regarding the improvement of the operational mechanisms aimed at increasing the efficiency of the financial, credit and tax mechanisms
The impact of the development of electronic commerce on the economy
Authors:   Azerbaijan State Economic University, Mammadbaghirova S.
Published: November 2023

E-commerce, the online buying and selling of goods and services, has transformed the global economic landscape over the past few decades. This article provides an in-depth analysis of the multifaceted impact of e-commerce development on the economy. It explores how the growth of e- commerce is changing traditional business models, consumer behavior and the wider economic environment. The article examines the positive aspects of the development of e-commerce, highlighting its role in promoting economic growth, job creation and global market expansion. It speaks to the accessibility and convenience that e-commerce offers consumers, enabling them to access a wider range of products and services, often at competitive prices.
Role and ımportance of outsourcıng servıce ın optımızatıon of busıness processes
Authors:   Azerbaijan University of Architecture and Construction, Yusifov E. , Eynullayev R. ,   Baku Eurasian University
Published: November 2023

Outsourcing of business processes is important in terms of strategic organization of the main activity of business subjects in an economy with dynamic development trends. In modern times, new features are formed in connection with the use of outsourcing by business subjects, and thus the nature of economic relations is changing. In the economic system where the use of outsourcing is newly formed, increasing the efficiency of its use is necessary from the point of view of obtaining economic prospects. In the article, the use of outsourcing strategy of companies is justified, the main advantages and disadvantages of its implementation are mentioned. On the basis of the organization of the advanced mechanism of outsourcing of business processes, the research was continued in the direction of increasing the efficiency in the activity of economic subjects.
B2B digital advertising: effective campaigns with google ads and linkedin
Authors:   Azerbaijan State University of Economics, İsmayılov R.
Published: November 2023

This article explores ways to run effective digital advertising campaigns in the B2B business-to-business sector and discusses how Google Ads and LinkedIn platforms can be used to do so. By comparing and contrasting these two major digital advertising platforms, companies can maximize their B2B marketing efforts. This article provides an overview of the strategies, benefits, and nuances of both platforms
The nature and importance of the monetary transmission mechanism
Authors:   Under the President of the Republic of Azerbaijan Academy of State Administration, Mammadov Y.
Published: November 2023

The sequence of processes necessary for the transmission of monetary policy to the economy is called the monetary transmission mechanism. Monetary transmission mechanism works through transmission channels. Thus, there are several types of these channels that exist for the policy applied by the Central Banks to be reflected in the economy. In the first chapter of the research work, the transmission channels are reported separately. Briefly, it can be noted that there are types of transmission channels such as traditional interest channel, exchange rate channel, bank-credit channel, asset price channel, balance sheet channel, part documents channel
Geo-economic development opportunities of Azerbaijan
Authors:   Azerbaijan State University of Economics, Nasirzadeh R.
Published: November 2023

The most important factor that increases the global and regional geo-economic and geo-political weight of Azerbaijan is its complete formation as an independent state, having a self-sufficient national economy, material, moral and human resources, a strong army and defense potential, and implementing an independent domestic and foreign policy. Our country is geographically located in one of the strategic positions, and is at the base of the main processes and transnational interests in the Caspian-Black Sea basin and the South Caucasus. Azerbaijan has reconciled the national interests of the country with the ever-increasing energy needs of the international world. By skillfully using the energy factor, attracting the attention of the leading states and power centers of the modern world to other national problems is considered one of the main national geo-economic and geo-political tasks of Azerbaijan in the modern era, and our country is skillfully fulfilling this task
Balancing efficiency, effectiveness and democracy in organizing inter-municipal partnerships
Authors: Andersen Ole Johan
Published: November 2023

The balancing of efficiency, effectiveness and democratic control is an ever-recurring problem when designing governance structures more or less disconnected from the formal democratic institutions. As far as the relationship between these considerations is concerned, much of the theoretical as well as the practical discourse revolve around the issue of whether synergy emerges or whether there is just a matter of trade-off. By applying primarily empirical observations from local-to-local cooperation in some Norwegian regions the article attempts to investigate how the relationship turns out. The article argues that at least three models are available, one balanced and two imbalanced variants. The notion of synergy highlights a model in which input- processes of democratic participation and output-processes of performance reinforce each other. The others, on the contrary, are imbalanced, implying either a democratic deficit or a deliberative surplus. By comparing the models to experiences from local-to-local cooperation a pattern of divergent features emerges. Nevertheless, a trade-off where the regard for local democracy and autonomy seems to dominate at the sacrifice of performing efficiently and effectively, thus the article is rather pessimistic as to what may be gained by pursuing the intermunicipal cooperative strategy further.
Why all this communication?
Authors: Nielsen Jeppe Agger , Salomonsen Heidi Houlberg
Published: November 2023

Public organizations are increasingly paying attention to strategic communication. However, the extant literature on public sector communication is predominantly descriptive, exploring how strategic communication is performed in practice, with little emphasis on why strategic communication has become so popular. Drawing on organizational institutional theory together with reports from a case study of strategic communication in Danish local governments, we take a first step towards explaining “all this communication”. Our results reveal how normative and mimetic institutional pressures occur, as key external stakeholders support and legitimize strategic communication while communicating general, yet detailed, instructions for performing strategic communication in a context of radical organizational changes. Moreover, we demonstrate how local governments translate strategic communication somewhat differently than external stakeholders, causing not only isomorphism but also heterogeneity in organizational strategies. Based on the empirical findings, we argue that strategic communication issues might benefit from being interpreted in a broader socio-political context rather than as a simple management tool for professionalizing public sector communication.
Decision making in large-scale language testing: Intersections of policy, practice and research
Authors:   Shanghai Jiao Tong University, Jin Yan
Published: November 2023

In this article, I delve into the intricacies of strategic decision making when a large-scale language test is reformed. Adopting a case study approach, I examine the activities involved in the reform of the College English Test (CET), an English language test for university students administered nationwide in the Chinese mainland (Zhang, 2022; Zheng & Cheng, 2008). In its 30+-year history, the CET has undergone several revisions and reforms (see Jin, 2010; 2020 for an overview). To illustrate how the major policies on test revision and reform have been formulated and implemented in this particular context, I present a brief overview of some major decisions that have been made over the decades. Through these cases, I hope to demonstrate the intricate interactions among policy intentions, professional requirements, ethical considerations, practical constraints, as well as the role of language testing professionals when strategic decisions are made to ensure a sustainable and healthy development of large-scale and high-stakes language tests.
НОВЕ МОНОГРАФІЧНЕ ДОСЛІДЖЕННЯ ІСТОРІЇ ЧЕРНІГІВСЬКОЇ ЄПАРХІЇ: Тарасенко О.Ф. Чернігівська єпархія у ХІХ – на початку ХХ ст. Чернігів: Десна Поліграф, 2022. 320 с.
Authors: Гейда Ольга
Published: November 2023

Чернігівська єпархія – одна з найдавніших і найбільших за територією церковних структур на теренах України. Заснована наприкінці Х ст., вона має величну історію, тісно вписану в загальноукраїнський літопис становлення Православної Церкви. Вивчення етапів її історії триває з різним результатом безперервно з середини XVII ст. і до сьогодні.
ГЛИНЯНІ ВИРОБИ В ПОХОВАЛЬНИХ ПАМ’ЯТКАХ ДАВНЬОРУСЬКОГО ЧАСУ (за матеріалами археологічних досліджень кінця ХІХ – другої половини ХХ ст.)
Authors: Троцька Валентина
Published: November 2023

Мета статті полягає в здійсненні аналізу праць археологів кінця ХІХ – другої половини ХХ ст., в яких досліджували глиняні вироби в похованнях давньоруського часу. Опрацьований матеріал дозволяє дійти висновків, що впродовж давньоруського часу існували два поховальні обряди – трупоспалення та трупопокладення небіжчиків. При обох видах поховань серед супровідного інвентарю знаходили різні типи глиняних виробів: горщики, глечики, миски, амфори, зооморфні та антропоморфні статуетки тощо. Наявність глиняних виробів у похованнях дослідники в першу чергу пов’язують із віруванням жителів у потойбічне життя, намаганням забезпечити покійного всім необхідним на тому світі, зокрема їжею та питвом, оскільки давньоруське населення вірило, що в потойбічні продовжується життя. Традиційною є думка, що в поховальній обрядовості речі, які клалися до могили, мали забезпечити потреби небіжчика після тілесної смерті.   Вдалося дослідити місцезнаходження та різні способи покладання глиняних виробів у могилах під час кремації та інгумації померлих, як у дорослих так і дитячих похованнях.
УКРАЇНСЬКА ДУХОВНА ПІСНЯ УСНОЇ ТРАДИЦІЇ: СТАН І ПЕРСПЕКТИВИ ДОСЛІДЖЕННЯ
Authors: Сироїд Олена
Published: November 2023

Авторка робить спробу визначити підходи, які б дозволили масштабне дослідження духовної пісні як явища народної традиції. З такою метою формується «погляд згори», так би мовити, зі сучасної точки зору на історію й стан українських народознавчих студій. Складність таких студій зумовлена передусім значною розпорошеністю відповідних рукописних та друкованих джерел, які при значній кількості мають здебільшого принагідний характер. Такій джерелознавчій специфіці розвідки відповідає поєднання історичного і порівняльного методів. Новизна й актуальність пов’язані, з одного боку – з фактом відсутності спеціальної наукової праці про духовну пісню в українській фольклористиці, з невивченістю історії фіксації текстів, як і спостережень щодо їх природи та функціонування; а з іншого – з безсумнівною цінністю цих творів, їх живучістю в усній традиції. У висновках накреслено перспективи дослідження української народної духовної пісні з акцентом на складності найактуальніших проблем, яку зумовлює багатство, різноманітність, об’ємність матеріалу.
НАСТУПНІСТЬ В ОРГАНІЗАЦІЇ ОСВІТНЬОЇ ДІЯЛЬНОСТІ ДОШКІЛЬНИКІВ І ПЕРШОКЛАСНИКІВ
Authors: Розлуцька Галина , Гірняк Світлана , Гуцол Людмила
Published: November 2023

Мета статті – висвітлити проблему наступності в організації освітньої діяльності дошкільників і першокласників, зокрема з розвитку зв’язного мовлення.
Методологія. Методологічною основою дослідження є системний підхід до аналізу наступності в організації освітньої діяльності дошкільників і першокласників, зокрема з розвитку зв’язного мовлення. Під час дослідження використано такі загальнонаукові методи: зіставно-порівняльний, функціонально-структурний аналіз наукових і навчально-методичних джерел, що сприяли розгляду проблеми наступності в освітній діяльності між дошкіллям та початковою школою; методи узагальнення дали змогу цілісно й об’єктивно схарактеризувати і висвітлити досліджувані процеси.
Наукова новизна отриманих результатів полягає в систематизації поглядів на проблему наступності під час організації освітньої діяльності дошкільників і першокласників, зокрема з розвитку зв’язного мовлення, оскільки урахування наступно-перспективних зв’язків в освітньому процесі уможливлює поетапне ускладнення навчального матеріалу, урахування індивідуальних особливостей учнів, застосування диференційованого та особистісно орієнтованого підходів до навчання як дошкільників, так і молодших школярів.
Висновки. Наступність – це не випадковий процес, це завжди необхідне, закономірне явище, що забезпечує поступовий розвиток, адже якщо в процесі освітніх змін відсутній елемент наступності, то це буде простим відтворенням, а не розвитком. Наступність – важлива умова цілісного й ефективного освітнього процесу, фактор, який визначає логіку і послідовність розвитку особистості, покроковий поступовий перехід від одного вікового етапу до наступного, її сутність виявляється у встановленні зв'язку в змісті навчального матеріалу, методах керівництва та формах організації освітнього процесу. Наступність у роботі з розвитку зв'язного мовлення дітей потребує координації зусиль вихователів закладів дошкільної освіти і вчителів початкової школи з метою забезпечення плавного переходу від ігрової до освітньої діяльності, формування вмінь правильно, зв'язно, грамотно, точно й доречно висловлюватися за зразком, аналогією або самостійно, зокрема відповідно до теми і мети спілкування.
Operating Artificial Intelligence to Assist Physicians Diagnose Medical Images: A Narrative Review
Authors: Adelaja Oluwaseun , Alkattan Hussein
Published: November 2023

Medical image diagnostics is crucial to healthcare since it aids in the diagnosis and treatment of a variety of diseases and conditions. However, the process is time-consuming and prone to human error. In recent years, artificial intelligence has been a powerful tool for enhancing medical imaging diagnosis. Using AI algorithms for medical picture interpretation has the potential to revolutionise the field by improving accuracy, efficacy, and standardization. These algorithms can quickly sift through enormous amounts of medical imaging, finding anomalies, quantifying features, and providing useful information to help medical professionals make judgments. AI-based systems can be used to track the evolution of diseases, plan treatments, and highlight particular areas of interest in medical pictures. Additionally, AI systems can aid in case triage by classifying cases according to urgency, enabling quick response to life-or-death situations. Healthcare practitioners can gain from increased diagnostic accuracy and efficiency, improved workflow management, and standardized interpretations by utilizing AI in medical imaging diagnostics. However, it's crucial to understand that AI complements human expertise rather than replacing it. To ensure a safe and efficient application in clinical settings as AI technologies continue to evolve and advance, continuing research and collaboration between AI developers and healthcare practitioners is essential. Medical image diagnosis is poised to advance significantly with continued AI integration, ultimately improving patient outcomes and healthcare delivery.
Two new species of Scolopocryptops centipedes from southern Japan (Chilopoda: Scolopendromorpha: Scolopocryptopidae)
Authors: Jonishi Taro , Nakano Takafumi
Published: November 2023

The blind centipede genus Scolopocryptops Newport, 1844 comprises two lineages: the “Asian/North American” group and the “Neotropical/Afrotropical” group. The former can be further split into two groups, a clade comprising Scolopocryptops elegans (Takakuwa, 1937) and Scolopocryptops curtus (Takakuwa, 1939), and a clade comprising all other “Asian/North American” species. Here, Scolopocryptops miyosii sp. nov. from Kyushu and Amami Island and Scolopocryptops brevisulcatus sp. nov. from Izena Island and Okinawa Island in southern Japan are described. The two new species have external features similar to S. elegans and S. curtus. They can be distinguished from most other “Asian/North American” Scolopocryptops by the absence of complete sulcus/sulci along the lateral margin of the cephalic plate and the presence of sternal longitudinal sulci. They can be distinguished from each other by several external features, such as the density of antennal setae and the shape of the anterior margin of the coxosternite. Phylogenetic analyses using nuclear and mitochondrial markers also support the monophyly of the four species, which form a clade sister to all other “Asian/North American” Scolopocryptops.
Penerapan Perkembangan Kognitif Jean Piaget dan Perkembangan Bahasa Vygotsky dalam Pembelajaran
Authors: Habsy Bakhrudin All , Rachmawati Amalia Putri , Wiyono Rima Faradillah Wati Fidaus , Rakhmanita Aulia
Published: November 2023

In this research, researchers are interested in examining the application of Jean Piaget's cognitive development and Vygotsky's language development in learning. The aim of this research is to deepen understanding of the application of Jean Piaget's cognitive theory and Vygotsky's language theory in learning. In his research, the researcher used a qualitative approach through literature study. Literature study is the object studied in this research, namely the application of Jean Piaget's cognitive development and Vygotsky's language development. The results of this research can be said that language development is closely related to cognitive development.
PROYECTO DEL PRIMER CÓDIGO DE ÉTICA DE LA SOCIEDAD ARGENTINA DE SEXUALIDAD HUMANA
Authors: GONCALVES MEIRA ROSANGELA GONCALVES , HAYQUEL EMILIANO
Published: November 2023

El Proyecto del primer Código de Ética de SASH, presentado por la Dra. Rosangela Gonçalves Meira y por el Dr. Emiliano Hayquel. Contó con la colaboración interdisciplinaria del Dr. Claudio Capuano, la Lic. Carolina Crespo, la Lic. Andrea Cordobes y el Dr. Federico Drigani
Pengaruh leverage, likuiditas, dan profitabilitas terhadap agresivitas pajak (Studi pada perusahaan sektor industri barang konsumsi yang terdaftar di Bursa Efek Indonesia tahun 2019-2022)
Authors: Simanungkalit Grace Ezra Aulia Deborah , Budiarso Novi Swandari , Korompis Claudia
Published: November 2023

Companies often view tax as a burden that reduces net profit, resulting in them tending to take action to minimize the tax burden or what is called tax aggressiveness. Several factors that can influence tax aggressiveness are leverage . liquidity , and profitability. The aim of this research is to determine the influence of Leverage , Liquidity and Profitability on Tax Aggressiveness in Consumer Goods Industry Sector Companies Listed on the Indonesia Stock Exchange in 2019 - 2022. Leverage is measured using the debt to assets ratio calculation , liquidity is measured using the current ratio calculation , profitability is measured using the return on assets calculation , and tax aggressiveness is measured using the effective tax rate . This type of research is quantitative research with a sampling technique, namely purposive sampling consisting of 30 samples from 51 populations and using multiple linear regression analysis with data processing via IBM SPSS 26. Partial and simultaneous research results show that leverage , liquidity and profitability have an influence against tax aggressiveness.
Spor Bilimleri Fakültelerindeki Akademisyenlerin Etkili İletişim Becerilerinin Örgüt Kültürü Tipine Etkisi
Authors: Durmuş Gamze , Karacan Doğan Pınar
Published: November 2023

Bu çalışmanın amacı, Spor Bilimleri Fakültelerinde görev yapan akademisyenlerin iletişim becerileri değerlendirme düzeylerinin örgüt kültür tiplerine etki düzeyini ortaya çıkartmak ve aralarındaki ilişkiyi tespit etmektir. Araştırma ilişkisel tarama modeline göre tasarlanmıştır. Çalışmaya Türkiye’nin 7 farklı bölgesinden 13 üniversitenin spor bilimleri fakültesinde görev alan 50 kadın ve 180 erkek olmak üzere 230 akademisyen katılmıştır. Akademisyenlerin iletişim becerilerinin ölçülmesi için “İletişim Becerileri Değerlendirme Ölçeği” ile örgüt kültürü tiplerini ve kültür düzeylerini ortaya çıkarmak için “Örgüt Kültürü Ölçeği” kullanılmıştır. Verilerin analizinde SPSS-25 paket programı kullanılmış, anlamlılık düzeyi p<0.05 olarak alınmıştır. Aynı zamanda basit doğrusal regresyon analizi, Pearson korelasyon analizi, bağımsız örneklemler (Independent-Samples) t-testi analizi, One-Way ANOVA (Tek Yönlü Varyans Analizi) kullanılmıştır. Akademisyenlerin iletişim becerileri değerlendirme düzeyleri ile örgüt kültürü tiplerine ait puanlar arasında ve örgüt kültürünün geneline ilişkin elde edilen puanlar arasındaki ilişkiler ve akademisyenlerin iletişim becerileri değerlendirme düzeylerinin örgüt kültürü üzerinde pozitif yönde etkisinin olduğu tespit edilmiştir. Akademisyenlerin iletişim becerileri değerlendirme düzeylerine göre yaş, çocuk olma durumu, unvan, kurumda çalışma süresi ve yönetim tarzları arasında anlamlı bir farklılık olduğu, cinsiyet, medeni durum ve idari görev durumu arasında ise anlamlı farklılık olmadığı saptanmıştır. Akademisyenlerin örgüt kültürü tiplerine ait kültür düzeyleri ile örgüt kültürünün geneline ait kültür düzeylerine göre cinsiyet, yaş, medeni durum ve çocuk olma durumu arasında anlamlı farklılık bulunmazken unvan ve yönetim tarzına göre anlamlı farklılık bulunmuştur. Aynı zamanda kurumda çalışma süreleri açısından adhokrasi kültür tipine göre anlamlı bir farklılık bulunurken diğer kültür tiplerinde anlamlı farklılık bulunmamıştır. İdari görev durumu açısından ise pazar kültür tipine göre anlamlı farklılık bulunurken diğer kültür tiplerine göre anlamlı farklılık bulunmamıştır.
Electrospun Ag/Al2O3 fibers for removal of methylene blue
Authors:   , Waikasikarn Parom
Published: November 2023

In this work, electrospun Ag/Al2O3 fibers were prepared by the sol–gel electrospinning methods in order to apply as sorbent and catalyst in photocatalytic reaction for removal of methylene blue. The electrospun Ag/Al2O3 fibers at various silver concentrations (2, 5 and 10%w/w) and different calcination temperatures (350 and 500 oC) were prepared. The electrospun Ag/Al2O3 fibers were characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FTIR), UV-VIS spectroscopy, X-ray Diffraction Analysis (XRD) and nitrogen adsorption/desorption analysis. The phase of alumina in Ag/Al2O3 fibers was gamma-alumina phase and the average diameter of obtained fibers was 75 nm. The average diameters of silver particles in Ag/Al2O3 fibers ranged from 3 to 13 nm and were in the form of Ag0 and Ag2O.  Then the electrospun Ag/Al2O3 fibers were applied for the removal of methylene blue in water. The removal efficiency of methylene blue by adsorption process was mainly from the host alumina which showed the percent removal of 54.8%. However, the calcined 10%w/w Ag/Al2O3 fibers at 350oC enhanced the removal efficiency of methylene blue by photocatalytic degradation approximately 2 times (% removal of methylene blue was 25% for Al2O3 and 48% for calcined 10%w/w Ag/Al2O3 fibers at 350oC). As a result, the Ag/Al2O3 fibers (calcined 10%w/w Ag/Al2O3 fibers at 350oC) exhibited the great effectiveness in the removal of methylene blue in water with 95.3% removal (47.3% by adsorption process and 48.0% by photocatalytic degradation). In addition, the electrospun Ag/Al2O3 fibers were easily collected and can be reused up to 3 times without the loss of photocatalytic degradation performance.
Zinc oxide/graphene nanocomposites as novel electrode for electrochemical sensor
Authors:   , Kongsittikul Pongsakorn
Published: November 2023

Zinc Oxide (ZnO) nanorods were prepared using zinc acetate as a precursor via modified thermal pyrolysis method and used to synthesize ZnO/graphene (ZnO/G) nanocomposites. The as prepared nanocomposites were successfully synthesized by a facile room-temperature approach using the colloidal coagulation effect. Afterwards, ZnO/G nanocomposites were used for electrode surface modification in an electrochemical sensor for the simultaneous determination of cadmium (Cd2+) and lead (Pb2+). The results obtained from transmission electron microscopy and scanning electron microscopy showed that ZnO nanarods with an average diameter of 93 ± 21 nm were uniformly dispersed on G nanosheets. Moreover, the factors affecting the electrochemical sensitivity of this system for the simultaneous determination of Cd2+ and Pb2+ were optimized using square-wave anodic stripping voltammetry. Under the optimized conditions, this system provided the detection limits (S/N=3) of 0.6 and 0.8 µg·L-1 for Cd2+ and Pb2+, respectively and a linear range was found to be 10-200 µg·L-1. Furthermore, this system provided the satisfied results for determination of Cd2+ and Pb2+ in wastewater samples compared with a standard inductively coupled plasma-optical emission spectroscopy.
Fischer-Tropsch synthesis over cobalt supported on silica hollow sphere catalyst
Authors:   , Atchimarungsri Thachapan
Published: November 2023

A propose of this work studied the silica hollow sphere (SHS) for a proper characteristic of support in the Fischer-Tropsch synthesis (FTS) because the normally main problem of FTS reaction was being produced the broader hydrocarbon products on a commercial catalyst. Nevertheless, the hollow sphere shape of SHS catalyst had a wall of the core catalyst for steric restriction of hydrocarbon propagation. The cobalt metals were loaded on the SHS by wetness impregnation method and used in the FTS. The SHS was synthesized through emulsion process with water/oil/water (W/O/W) that used the sodium silicate for silica source and NH4HCO3 for the mesopore generating in the SHS support. The proper SHS catalyst in FTS showed higher specific surface area more than 500 m2/g and less micropore, causing diffusion elimination and mass transfer inside the pore, which resulted in the enhanced CO conversion more than 90 percent, lower C12+, and the narrower hydrocarbon selectivity. Moreover, the study of the coated zeolite that was ZSM-5 type on the SHS catalyst was two methods, which were hydrothermal synthesis and steam-assisted crystallization (SAC) process. The results of both methods represented the increase of narrower hydrocarbon products, isoparaffins and olefins selectivity due to acid sites of the zeolite. However, these methods as the improved cobalt based over SHS catalyst had some problems such as the decomposing of the silica, removing of cobalt metals on the SHS support and uncovering of some zeolite over the SHS catalysts.
PREPARATION OF BUTYLATED PHENOL DERIVATIVES USING ACIDIC HETEROGENEOUS CATALYSTS
Authors:   , Singhapan Warumporn
Published: November 2023

Propyl sulfonic acid functionalized SBA-15 and proton MCM-22 catalysts were synthesized by using hydrothermal method. The structure morphology and acidity of synthesized materials were characterized by X-ray powder diffraction, nitrogen sorption analysis, scanning electron microscopy and acidity measurement. Propyl sulfonic acid fuctionalized SBA-15 (SBA-15-Pr-SO3H) was tested catalytic activities in BisphenolA butylation and compared catalytic activity with Amberlyst-15 and other porous catalysts. The optimized condition when using SBA-15-Pr-SO3H was mole ratio of BisphenolA to MTBE of 1: 10, catalytic amount 15 wt% based on BisphenolA at 120oC for 8 hrs. The reaction mixture gave the highest total yield of products compared to those of other mesoporous catalysts. Moreover, the catalytic efficiency of HMCM-22 of butylation of BisphenolA was tested. Suitable reaction condition that gave the highest total product was optimized to be mole ratio of BisphenolA to tert-butanol as 1: 15, catalytic amount 10 wt% based on BisphenolA at 120oC for 8 hrs. The reaction mixture exhibited the highest total yield of alkylated products as 32.8%. In addition, the condition of continuous flow process to prepare 2,6-di-tert-butyl p-cumylphenol was optimized to be mole ratio of p-cumylphenol to MTBE of 1: 5, LHSV = 0.02 h-1, at 100oC. The results illustrated the highest 2,6-di-tert-butyl p-cumylphenol yield as 28.19%. The radical scavenging capacity of purified and reaction mixtures were measured to compare with their starting materials. It was found that antioxidant activity was increased as following order; BisphenolA < p-cumylphenol < 2-tert-butyl p-cumylphenol < BisphenolA products < 2,6-di-tert-butyl p-cumylphenol.
Development of elastic liposomes of caffeine for the treatment of cellulite
Authors:   , Kao-ian Chungrida
Published: November 2023

In this study, caffeine elastic liposomes were developed for cellulite treatment by using the combination of surfactant and ethanol. The elastic liposomes studied consisted of phosphatidylcholine as the structural lipid, Span® 80 or Tween® 80 of the same molar ratio (5-10% w/w and 15-25% w/w of total lipid, respectively) as the edge activator and various concentrations of ethanol (5-25% v/v). The effects of type and amount of surfactants and concentration of ethanol on physical properties i.e., vesicle formation, size and size distribution and elasticity of blank liposomes were investigated. The blank liposome formulations with highest elasticity of each surfactant were selected to prepare the caffeine-containing elastic liposomes. These elastic liposomes were characterized for physical properties including entrapment efficiency and physical stability. The skin delivery of caffeine from the chosen elastic liposome formulations were carried out in vitro with modified Franz diffusion cells under the non-occlusive condition using newborn pig skin as the model membrane. The results showed that the complete vesicle formation was observed at low ethanol concentrations (5-15% v/v). The vesicle size of liposomes composed of Span® 80 and Tween® 80 was in the range of 5.84-8.08 µm and 3.73-5.27 µm, respectively. The combination of surfactant and ethanol showed significant effects on physical properties of elastic liposomes. The elasticity of liposomes containing Span® 80 and Tween® 80 was in the range of 27.07-79.86% and 8.44-15.74%, respectively. The formulations with highest elasticity, S7.5_5 with Span® 80 7.5% w/w and ethanol 5% v/v and T20_5 with Tween® 80 20% w/w and ethanol 5% v/v, were chosen to load caffeine. In general, physical properties of caffeine elastic liposomes were similar to the corresponding blank liposomes. However, caffeine loading decreased the elasticity of caffeine-entrapped elastic liposome formulations by approximately 20-30% compared to that of the blank elastic liposomes. The elasticity values of the caffeine-loaded elastic liposome formulations S7.5_5 and T20_5 were 53.46±8.63% and 11.93±0.46%, respectively. The entrapment efficiency values of S7.5_5 was lower than that of T20_5 (35.05±0.60 and 41.31±3.32% w/w, respectively). Skin permeation from S7.5_5 and T20_5 were significantly higher than that from the hydro-alcoholic solution used as the aqueous phase of these elastic liposomes. However, despite the profound difference in elasticity between the 2 formulations, no significantly differences were seen in most permeation parameters studied. The only significant difference detected was the enhancement factor of caffeine amount in the skin, the mean of which was almost doubled for the S7.5_5 formulation when compared to the T20_5 formulation.
Formulation development of celecoxib-cyclodextrin suspensions for ophthalmic delivery
Authors:   , Kulsirachote Pakin
Published: November 2023

Celecoxib (CCB), a nonsteroidal anti-inflammatory drug (NSAID), could be beneficial in the treatment of age-related macular degeneration (AMD) and diabetic retinopathy (DR) through the inhibition of COX-2 enzyme. Currently, the several methods can deliver drugs to the back of the eye. i.e., oral, intravitreal injection, subconjunctival injection and topical. Among routes of administration, topical eye drop is non-invasive method and local effects. However, due to low aqueous solubility of CCB, it hampers ocular bioavailability. Thus, the aim of this study was to develop topical eye drop suspensions containing cyclodextrin (CD) and polymer delivering to the posterior segment of the eye. CDs, the solubilizer, i.e., alpha-CD, beta-CD, gamma-CD, HP-beta-CD and RM-beta-CD and mucoadhesive polymers i.e., hydroxypropylmethylcellulose (HPMC) chitosan and hyaluronic acid (HA) were used. The phase solubility profiles and CCB/CD complex characteristics were investigated. RM-beta-CD exhibited the greatest solubilizer among CDs tested. HPMC was the potential polymer to form ternary complex with CCB/RM-beta-CD which gave 11-folds complexation efficiency higher than that of its binary complex. The aggregate size of ternary complexes in solution were found in the range of 250 - 350 nm which could solubilize themselves resulting in increasing CCB solubility. The data obtained from FT-IR, DSC, PXRD and 1H-NMR indicated that there were interaction of CCB with CD as inclusion complex. The CCB eye drops formulations were prepared by unheated and heating method (sonication at the temperature of 70oC for 1 hour). The physicochemical and chemical characterizations, mucoadhesive properties and in-vitro permeation were determined. The physicochemical properties i.e., appearance, pH, osmolality and viscosity were in acceptable range. The particle sizes below 10 µm indicated possibly no irritation to the eye. The formulation containing HA showed the excellent mucoadhesive properties. The increasing of % CCB content in most cases by heat resulting in higher flux permeation through semipermeable membrane and through simulated artificial vitreous humor, especially the formulation containing RM-beta-CD and HA (0.5% w/v). Therefore, it may be a promising candidate as topical formulation which can deliver CCB to the posterior segment of eye to treat AMD and DR.
Development of fluocinolone acetonide microemulsion mouthwash
Authors:   , Chukaewrungroj Pataravadee
Published: November 2023

โรคไลเคนพลานัสในช่องปาก (Oral lichen planus) เป็นโรคที่มีอาการอักเสบเรื้อรังที่เยื่อบุในช่องปาก เชื่อว่าเกิดจากความผิดปกติของระบบภูมิคุ้มกัน แผลในช่องปากชนิดที่มีการฝ่อและการกร่อนของเนื้อเยื่อมักเป็นสาเหตุของความเจ็บปวด มีการนำยาคอร์ติโคสเตียรอยด์เฉพาะที่เพื่อลดอาการอักเสบและความเจ็บปวด และมีรายงานว่าตัวยาฟลูโอซิโนโลนอะเซโทไนด์มีประสิทธิภาพในการลดความรุนแรงของแผลชนิดที่มีการฝ่อและการกร่อน โดยไม่มีอาการข้างเคียงที่รุนแรง ดังนั้นยาฟลูโอซิโนโลนอะเซโทไนด์ในรูปแบบน้ำยาบ้วนปากจึงเป็นตำรับที่น่าสนใจในการรักษาโรคไลเคนพลานัสในช่องปาก ไมโครอิมัลชันจึงถูกเลือกมาเพื่อเตรียมเป็นน้ำยาบ้วนปากเพื่อเพิ่มค่าการละลายและความคงตัวของตัวยาฟลูโอซิโนโลนอะเซโทไนด์ วัตถุประสงค์ของการศึกษานี้คือเพื่อตั้งตำรับน้ำยาบ้วนปากในรูปของไมโครอิมัลชันและพรีไมโครอิมัลชันเข้มข้นที่มีตัวยาฟลูโอซิโนโลนอะเซโทไนด์ ซึ่งได้ประเมินความคงตัวทางกายภาพและเคมีของตำรับน้ำยาบ้วนปาก และกำหนดวันที่ควรใช้ก่อนของตำรับ จากการสร้างเฟสไดอะแกรมซึ่งประกอบด้วยน้ำมันกานพลูหรือน้ำมันเปปเปอร์มินท์เพื่อตั้งตำรับไมโครอิมัลชัน พบว่าการใช้สารลดแรงตึงผิวผสมที่อัตราส่วน 2:1 ของทวีน 80 กับโพลีเอทิลีนไกลคอล 400 ทำให้ได้เฟสไดอะแกรมที่มีพื้นที่ไมโครอิมัลชันกว้างกว่าการใช้สารลดแรงตึงผิวผสมที่อัตราส่วน 1:1 ส่วนประกอบที่เหมาะสมได้แก่ น้ำมันกานพลู 3.5% สารลดแรงตึงผิวผสม 31.5% และน้ำ 65% ซึ่งมีค่าการละลายของยาฟลูโอซิโนโลนอะเซโทไนด์ในช่วงที่ยอมรับได้และสามารถเตรียมไมโครอิมัลชันที่มีตัวยาฟลูโอซิโนโลนอะเซโทไนด์ 0.1% นอกจากนี้ยังเตรียมพรีไมโครอิมัลชันเข้มข้นด้วยอัตราส่วนเดียวกัน จากนั้นได้ทำการศึกษาความคงตัวทางกายภาพและเคมีของตำรับไมโครอิมัลชันและพรีไมโครอิมัลชันเข้มข้น และศึกษาผลต่อความคงตัวทางเคมีเมื่อมีการเติมสารต้านออกซิเดชัน หลังจากเก็บตำรับน้ำยาบ้วนปากเป็นเวลา 6 เดือน พรีไมโครอิมัลชันเข้มข้นและไมโครอิมัลชันทุกตำรับมีความคงตัวทางกายภาพที่ดี อย่างไรก็ตามพบว่าในพรีไมโครอิมัลชันเข้มข้นมีปริมาณยาฟลูโอซิโนโลนอะเซโทไนด์ลดลงมากกว่าในไมโครอิมัลชัน อาจอธิบายได้จากในไมโครอิมัลชันมีการกักเก็บยาฟลูโอซิโนโลนอะเซโทไนด์อยู่ในเฟสน้ำมันภายใน จึงทำให้แยกตัวยาออกจากสารไม่บริสุทธิ์ที่เจือปนหรือสารกลุ่มที่เกิดปฏิกิริยาได้ง่ายที่สามารถเร่งการสลายตัวของยา ในขณะที่สารเหล่านี้กระจายตัวทั่วในตำรับพรีไมโครอิมัลชันเข้มข้น นอกจากนี้การกำหนดวันที่ควรใช้ก่อนของไมโครอิมัลชันยาฟลูโอซิโนโลนอะเซโทไนด์ได้ที่อายุ 12 เดือน ซึ่งยาวกว่าพรีไมโครอิมัลชันเข้มข้นยาฟลูโอซิโนโลนอะเซโทไนด์