bluuebunny/crossref_metadata_2025 huggingface dataset:
Primary hip and knee arthroplasty in a temporary operating theatre is associated with a significant increase in deep periprosthetic infection
Authors: Bloch B. V. , Shah A. , Snape S. E. , Boswell T. C. J. , James P. J.
Published: June 2017

Aims

Infection following total hip or knee arthroplasty is a serious complication. We noted an increase in post-operative infection in cases carried out in temporary operating theatres. We therefore compared those cases performed in standard and temporary operating theatres and examined the deep periprosthetic infection rates.

Patients and methods

A total of 1223 primary hip and knee arthroplasties were performed between August 2012 and June 2013. A total of 539 (44%) were performed in temporary theatres. The two groups were matched for age, gender, body mass index and American Society of Anesthesiologists grade.

Results

The deep infection rate for standard operating theatres was 0 of 684 (0%); for temporary theatres it was eight of 539 (1.5%) (p = 0.001).

Conclusion

Use of a temporary operating theatre for primary hip and knee arthroplasty was associated with an unacceptable increase in deep infection. We do not advocate the use of these theatres for primary joint arthroplasty. Cite this article: Bone Joint J 2017;99-B:917–20.
An epidemic of the use, misuse and overdose of opioids and deaths due to overdose, in the United States and Canada
Authors: Helmerhorst G. T. T. , Teunis T. , Janssen S. J. , Ring D.
Published: June 2017

The United States and Canada are in the midst of an epidemic of the use, misuse and overdose of opioids, and deaths related to overdose. This is the direct result of overstatement of the benefits and understatement of the risks of using opioids by advocates and pharmaceutical companies. Massive amounts of prescription opioids entered the community and were often diverted and misused. Most other parts of the world achieve comparable pain relief using fewer opioids.

The misconceptions about opioids that created this epidemic are finding their way around the world. There is particular evidence of the increased prescription of strong opioids in Europe.

Opioids are addictive and dangerous. Evidence is mounting that the best pain relief is obtained through resilience. Opioids are often prescribed when treatments to increase resilience would be more effective.

Cite this article: Bone Joint J 2017;99-B:856–64.
Superior mesenteric artery syndrome: a single centre experience of laparoscopic duodenojejunostomy as the operation of choice
Authors: Kirby GC , Faulconer ER , Robinson SJ , Perry A , Downing R
Published: June 2017

INTRODUCTION

The superior mesenteric artery (SMA) syndrome, or Wilkie’s syndrome, is a rare cause of postprandial epigastric pain, vomiting and weight loss caused by compression of the third part of the duodenum as it passes beneath the proximal superior mesenteric artery. The syndrome may be precipitated by sudden weight loss secondary to other pathologies, such as trauma, malignancy or eating disorders. Diagnosis is confirmed by angiography, which reveals a reduced aorto-SMA angle and distance, and contrast studies showing duodenal obstruction. Conservative management aims to increase intra-abdominal fat by dietary manipulation and thereby increase the angle between the SMA and aorta. Where surgery is indicated, division of the ligament of Treitz, anterior transposition of the third part of the duodenum and duodenojejunostomy have been described.

METHODS

We present four cases of SMA syndrome where the intention of treatment was laparoscopic duodenojejunostomy. The procedure was completed successfully in three patients, who recovered quickly with no short-term complications. A fourth patient underwent open gastrojejunostomy (complicated by an anastomotic bleed) when dense adhesions prevented duodenojejunostomy.

CONCLUSIONS

The superior mesenteric artery syndrome should be considered in patients with epigastric pain, prolonged vomiting and weight loss. Laparoscopic duodenojejunostomy is a safe and effective operation for management of the syndrome. A multi-speciality team approach including gastrointestinal, vascular and radiological specialists should be invoked in the management of these patients.
Selective non-operative management of abdominal stab wounds is a safe and cost effective strategy: A South African experience
Authors: Dayananda KSS , Kong VY , Bruce JL , Oosthuizen GV , Laing GL , Clarke DL
Published: June 2017

INTRODUCTION

Selective non-operative management (SNOM) of abdominal stab wounds is well established in South Africa. SNOM reduces the morbidity associated with negative laparotomies while being safe. Despite steady advances in technology (including laparoscopy, computed tomography [CT] and point-of-care sonography), our approach has remained clinically driven. Assessments of financial implications are limited in the literature. The aim of this study was to review isolated penetrating abdominal trauma and analyse associated incurred expenses.

METHODS

Patients data across the Pietermaritzburg Metropolitan Trauma Service (PMTS) are captured prospectively into the regional electronic trauma registry. A bottom-up microcosting technique produced estimated average costs for our defined clinical protocols.

RESULTS

Between January 2012 and April 2015, 501 patients were treated for an isolated abdominal stab wound. Over one third (38%) were managed successfully with SNOM, 5% underwent a negative laparotomy and over half (57%) required a therapeutic laparotomy. Over five years, the PMTS can expect to spend a minimum of ZAR 20,479,800 (GBP 1,246,840) for isolated penetrating abdominal stab wounds alone.

CONCLUSIONS

Provided a stringent policy is followed, in carefully selected patients, SNOM is effective in detecting those who require further intervention. It minimises the risks associated with unnecessary surgical interventions. SNOM will continue to be clinically driven and promulgated in our environment.
A systematic review of questionnaires used to measure the time spent on family care for frail older people
Authors: Cès Sophie , Mello Johanna De Almeida , Macq Jean , Durme Thérèse Van , Declercq Anja , Schmitz Olivier
Published: June 2017

Time spent on family care of frail older people is difficult to substantiate because of its complex nature. The aim of this study is to check the content validity of existing questionnaires measuring the time spent on caring. Comparing the activities mentioned in the questionnaires with those from other data sources (three validated scales measuring the functional limitations in day-to-day activities and a qualitative study) enabled identification of important drawbacks in the questionnaires reviewed. A comprehensive list of activities was built in order to help future researchers to conduct effective data collection and thereby enable an in-depth analysis of family care supply.
Evolución del montaje y postproducción del videoclip musical: del jumpcut a los VFX como paradigma de iconicidad y puesta en escena
Authors: Jódar-Marín Juan-Ángel
Published: June 2017

Esta investigación tiene por objeto determinar la evolución del discurso formal del videoclip mediante el montaje y la postproducción audiovisual, desde su aparición hasta el actual contexto mediático con la implementación del tratamiento digital aplicado al ámbito de los efectos visuales. Tras un largo periodo de hegemonía cultural en los años 80 y 90, la industria discográfica se vio afectada por una crisis profunda unida a una redefinición de las condiciones de producción y distribución. En ese contexto, y fruto de esa situación, comenzó el resurgimiento del videoclip gracias al papel tan relevante ejercido por Internet y, concretamente, las plataformas de alojamiento de vídeos como Youtube, favoreciendo una expansión sin precedentes de la distribución de contenidos audiovisuales por la Red y convirtiéndose en la vía de consumo masivo del videoclip. El estudio se inicia con el análisis del ritmo, como base discursiva elemental de la articulación sincrónica de imagen y música, hasta el estudio de las tendencias más frecuentes en cuanto a aspectos concretos de postproducción y efectos visuales.
Una propuesta integral de medición de las migraciones forzadas. El caso de la población de origen colombiano en el País Vasco
Authors: Fernández Aragón Iraide , Fouassier Zamalloa Maite , Moreno Márquez Gorka
Published: June 2017

En este artículo planteamos una propuesta de medición de las migraciones forzadas que pueda trascender las limitaciones normativas que han hecho que en los últimos años el número de solicitudes de asilo se hayan visto reducidas drásticamente en la mayoría de países europeos. Para ello, se realiza un sondeo a la población de origen colombiano residente en la Comunidad Autónoma del País Vasco (CAPV) para detectar las vulneraciones de derechos y, a partir del trabajo de ponderación de un grupo de expertos en la materia, se ofrecen diferentes estimaciones para superar las limitaciones asociadas a la categoría jurídica de refugiado. Los resultados muestran que el número de personas de origen colombiano residiendo en la CAPV que manifiestan un desplazamiento forzado por circunstancias de vulneración de sus derechos es del 6% (Desplazamiento manifiesto). Sin embargo, creemos que esta aproximación invisibiliza parte del fenómeno, de hecho, las estimaciones realizadas a partir de los datos indicarían que entre un 17,2% y un 22,9% de las migraciones de origen colombiano podrían deberse a un desplazamiento forzado (Desplazamiento atribuido).
Me aconsejaron o casi me obligaron a ser ‘normal’. Análisis de las barreras de exclusión a partir de historias de vida de mujeres lesbianas y bisexuales
Authors: Francisco Amat Andrea , Moliner Miravet Lidon
Published: June 2017

El objetivo de este artículo es mostrar los resultados del análisis de 19 historias de vida de mujeres lesbianas y bisexuales para indagar sobre las barreras de exclusión que han estado presentes en su experiencia vital. El análisis de los relatos se ha realizado utilizando el modelo Encontrando Vidas (Francisco y Moliner, 2015). Los resultados evidencian cómo el sistema heteronormativo, entendido como eje central de opresión de cualquier identidad, rol, práctica u orientación que se salga de la norma, atraviesa las vivencias personales a todos los niveles, mostrando la necesidad de continuar trabajando para que todas las personas sean ciudadanas de pleno derecho
La satisfacción con la vida de las personas extranjeras en España durante la crisis económica
Authors: García Utrera Sandra , Guardiola Jorge
Published: June 2017

En este trabajo pretendemos analizar los determinantes de la satisfacción con la vida de los/as inmigrantes en España y las diferencias con los/as autóctonos/as. Las preguntas clave son las siguientes: ¿Es más infeliz la población inmigrante que la autóctona? ¿Existen diferencias entre los distintos factores relacionados con la felicidad de ambas poblaciones? Los resultados indican que, controlando por variables económicas y sociales, los/as inmigrantes están más insatisfechos/as que los/as autóctonos/as.  Sin embargo, los resultados sugieren que el impacto de la crisis y las diferencias de ingresos condicionan la relación entre ser inmigrante y la satisfacción con la vida.
The impact of oral rehabilitation on quality of life by installing a fixed prosthesis with immediate loading in edentulous mandibles
Authors: Palma Pamella Valente , Vilela Eduardo Machado , Leite Isabel Cristina Gonçalves
Published: June 2017

Objective: This study assessed the impact of oral rehabilitation with immediate-loading fixed prostheses on the quality of life of patients with mandibular edentulism. Materials and Methods: A longitudinal study was conducted on an outpatient basis. The sample included 14 patients over 18 years of age, treated in the Implantology Specialization programs of the Brazilian Dental Association (in Juiz de Fora, Brazil) and the School of Dentistry, Federal University of Juiz de Fora. Participants were interviewed about identification data, self-perceived general health and oral health, and socioeconomic data. The Oral Health Impact Profile (OHIP-14) was used. After the Kolmogorov-Smirnov normality test, the OHIP-14 central tendency values were compared using the Wilcoxon paired test with a 5% significance level. Results: The overall mean found for the quality of life questionnaire was 30.14 (before) and 48.93 (after). There was a significant reduction of impact in all areas in the post-surgical period, except for functional limitation. No impact was identified for the dimensions of physical pain and disability after installing implants. Conclusion: Prosthetic rehabilitation and self-perception have high impact on oral health, thus emphasizing the need for care, careful observation of all the factors that may have an influence on infirmities, and not only their signs and symptoms.
Tooth preparations: science & art. Author: Clovis Pagani, Co-workers: Eduardo Galera da Silva, Daniel Maranha da Rocha. Hanover Park, Illinois: Quintessence; 2017. ISBN: 978-1-78698-001-4.
Authors: Rodrigues José Roberto
Published: June 2017

Tooth preparations: science & art AutorAuthorClovis Pagani - São Paulo State University (Unesp) - Institute of Science and Technology - Restorative Department  –  São José dos Campos - SP – Brazil.co-workers Eduardo Galera da Silva -   São Paulo State University (Unesp) - Institute of Science and Technology   -  Social and Pediatric Dentistry Department - São José dos Campos – SP – Brazil.Daniel Maranha da Rocha -    University of Sergipe -  Department of Dentistry of Lagarto- Lagarto - SE -  Brazil.Publisher: Quintessence Pub Co; 1 ed. (31 May 2017)Language: EnglishISBN: 978-1-78698-001-4.
Evaluación de interfaces de explicación en los sistemas de recomendación - Evaluation of explanation interfaces in recommendation systems
Authors: Cleger-Tamayo Sergio , Picanço-Pessoa Marcela Sávia , Figueiras- de Farias Marcella Sarah
Published: June 2017

Las interfaces de explicación se tornan una herramienta útil para los sistemas con una alta cantidad de contenido a ser evaluado por los usuarios. Las diferentes interfaces representan una ayuda para los usuarios indecisos o aquellos que consideran los sistemas una caja cerrada inteligente. Estos sistemas muestran recomendaciones a los usuarios basados en diferentes modelos. En el presente trabajo se presentan los diferentes objetivos perseguidos con las interfaces y algunos de los criterios que pudieran ser analizados, así como una propuesta de métricas para registrar resultados. Se muestran finalmente los principales resultados de un estudio con usuarios reales y su interacción con sistemas de uso cotidiano. Dentro de las principales conclusiones destaca el impacto positivo en relación al tiempo de interacción con los aplicativos y la aceptación de las recomendaciones recibidas.
Sistema tutor para la aplicación de la programación mediante análisis de inteligencias - Tutor system for the application of programming through intelligence analysis
Authors: Machín-Torres Ivelisse Teresa
Published: June 2017

El presente artículo forma parte de la investigación para la elaboración de un sistema tutor inteligente, que permita la aplicación de la programación mediante análisis de inteligencias y conceptos en la Universidad José Martí de Sancti–Spíritus (UNISS). El objetivo de la implementación de este sistema es potenciar la gestión del conocimiento referido a los temas de programación y mejorar la orientación en la solución de problemas relacionados con el aprendizaje dentro de la universidad. Para llevar a cabo la implementación del sistema tutor inteligente fueron analizados con alto nivel de profundidad los sistemas tutores existentes dentro del ámbito de la programación a nivel nacional e internacional; se describieron las herramientas y tecnologías utilizadas en la solución desarrollada (metodología, patrones, herramientas informáticas, lenguajes de programación, etc.) que permitieron una implementación eficiente en tiempo prudencial del sistema propuesto. Lo antes descrito se refleja de manera positiva en una mejor satisfacción de los estudiantes, y por consiguiente, en un mayor rendimiento en el proceso enseñanza aprendizaje de la universidad.
MODELO DE INVESTIGACIÓN EN INGENIERÍA APOYADO POR LA GESTIÓN DEL CONOCIMIENTO
Authors: Rodriguez Bernal Luis Leonardo , Medina García Víctor Hugo , Giraldo Marín Lillyana María , Lopez Quitero Jose Fernado
Published: June 2017

Este artículo presenta un modelo de investigación en ingeniería basado en estrategias de gestión del conocimiento, el cual pretende mejorar las relaciones entre la academia, la investigación y la empresa, con el propósito de reducir la brecha existente entre el factor de información y de conocimiento, a fin de fortalecer la investigación en ingeniería.Para dicho propósito se empleó la teoría de la complejidad aplicada a los grupos de investigación académicos, donde se espera relacionar las características que le son propias y aportar conjuntamente soluciones a los problemas de la sociedad actual, especialmente en la aplicación de las posibles innovaciones (nuevas o de conocimientos mejorados) encontradas con el apoyo de la empresas pública o privada.Model engineering research supported by knowledge managementABSTRACTThis paper presents a model of research in engineering based on strategies for knowledge management, which aims to propose better relationships between the academy, the research and the business sector that look for bringing down the gap existed in the information field and knowledge to strengthen the research in engineering. For this purpose, it was employed the complexity theory, applied to the academic research groups where it is expected to relate the features that are implicitly stated looking for providing common solutions to the problems presented in the current society; especially in the implementation of the possible innovations (new or improved knowledge) found with the support of the public or private companies.Keywords: academy, engineering, enterprise, knowledge management, model, research.
Recycling of Mineral Water Bottles with Chemical Foaming
Authors: Szabó V. A. , Dogossy G.
Published: June 2017

Today, in the field of packaging technologies there is an increasing amount of one-way polymer materials. Such materials after their short lifecycle are disposed, and such pose a serious environmental impact. However, PET is a good quality technical plastic; the recycled use must be provided. In our research, we have examined the recycled material of mineral water bottles. Chemical foaming of recycled polyethylene terephthalate (rPET) was applied for quality increased reusability. Significant results were achieved in terms of mechanical properties at specific mixtures of chain extender and impact resistance enhancer, at the foaming state of the injection moulding.
Wprowadzenie. Wyzwania instytucjonalnej ewaluacji nauki
Authors: Kulczycki Emanuel
Published: June 2017

Wprowadzenie
A new twist to Sin3 complexes in pluripotent cells
Authors: Pantier Raphaël , Mullin Nicholas P , Chambers Ian
Published: June 2017

Sin3a is a central component of a class of histone deacetylase‐containing transcriptional co‐regulatory complexes. In this issue of The EMBO Journal, Streubel et al () purify Sin3a and identify a variant Sin3a complex containing Fam60a in undifferentiated embryonic stem cells (ESCs). Fam60a is a critical component of the ESC Sin3a complex since Fam60a knockdown leads to an extended G1 cell cycle phase and reduced ESC self‐renewal. These exciting results open up new questions about how biochemical differences between variant Sin3a complexes may facilitate alterations in cell‐specific function.
ШЛЯХИ ЗАЛУЧЕННЯ ДОДАТКОВИХ ІНВЕСТИЦІЙ В ЕКОНОМІКУ УКРАЇНИ
Authors: Boreiko V.I.
Published: June 2017

В статті досліджено роль інвестиційних ресурсів в забезпеченні динамічного розвитку економіки країни; проаналізовано динаміку надходження прямих іноземних інвестицій в Україну та депозитів населення, залучених комерційними банками; обґрунтовано, що, для створення сприятливого середовища для інвесторів, Україні необхідно посилити правовий захист комерційних інтересів інвесторів, надати їм податкові пільги, забезпечити страхування їх виробничих і комерційних ризиків, скасувати оподаткування депозитів громадян та відшкодовувати їм всю суму вкладів при банкрутстві комерційних банків.
МЕХАНІЗМ ФІНАНСОВОГО ЗАБЕЗПЕЧЕННЯ ІННОВАЦІЙНОГО РОЗВИТКУ РЕГІОНУ
Authors: Shchur R. I. , Plets' I. I. , Mykytyuk O. V.
Published: June 2017

На етапі переходу країни до інноваційної моделі розвитку економіки дієвий механізм фінансового забезпечення інноваційного розвитку є надзвичайно вагомим та незамінним каталізатором  інноваційних процесів. Стаття спрямована на дослідження складових механізму фінансового забезпечення інноваційного розвитку регіонів. Досліджено динаміку джерел фінансування інноваційного розвитку Івано-Франківської області. Зазначено особливості у фінансовому забезпеченні інноваційного розвитку Прикарпатського  регіону за рахунок власних, бюджетних коштів, кредитів та зовнішнього фінансування. Виявлено недостатність державних, кредитних джерел фінансування інновацій, або і взагалі їх відсутність, в Івано-Франківській області, хоч за інноваційним потенціалом вона займає лідируючі позиції серед всіх регіонів країни. Відображено проблеми податкового стимулювання інноваційних процесів в області та в державі в цілому. Запропоновано збільшити обсяги державного забезпечення досліджуваної області та удосконалити податкове стимулювання інноваційного розвитку.
ОБЛІКОВО-АНАЛІТИЧНЕ ЗАБЕЗПЕЧЕННЯ ДЕБІТОРСЬКОЇ ЗАБОРГОВАНОСТІ В СІЛЬСЬКОГОСПОДАРСЬКИХ ПІДПРИЄМСТВАХ
Authors: Bondarchuk N.V. , Vasilyeva L.M.
Published: June 2017

Стаття спрямована на дослідження обліково-аналітичного забезпечення дебіторської заборгованості в сільськогосподарських підприємствах. Метою даної статті є комплексне дослідження теоретико-методичних положень щодо удосконалення обліково-аналітичного забезпечення дебіторської заборгованості в сільськогосподарських підприємствах. Визначено, що сільськогосподарські підприємства повинні постійно здійснювати моніторинг наявності та погашення дебіторської заборгованості. Такий постійний моніторинг управління дебіторською заборгованістю дозволяє не тільки ефективно розподіляти фінансові потоки, але й успішно прогнозувати основні зміни, уникати великої кількості проблем та підвищувати рівень конкурентоспроможності підприємств на сучасному ринку.

Встановлено, що на величину дебіторської заборгованості підприємств впливає цілий ряд факторів, а саме: якість аналізу дебіторської заборгованості та послідовність у використанні його результатів, платіжна дисципліна покупців і загальний економічний стан галузей, до яких вони належать, система розрахунків, яка застосовується на підприємстві, умови договорів з контрагентами, умови розрахунків з покупцями та замовниками та інші.

Розглянуто документи, в яких ведеться облік дебіторської заборгованості. Встановлено, що сучасна обліково-аналітична система дебіторської заборгованості не завжди надає повну, неупереджену облікову інформацію для проведення аналізу дебіторської заборгованості сільськогосподарських підприємств. Для забезпечення своєчасності та повноти обліку наявної дебіторської заборгованості запропоновано сільськогосподарським підприємствам використовувати такий регістр аналітичного обліку, як «Аналітична картка обліку договорів».
РОЛЬ ФІНАНСОВИХ ІНСТИТУЦІЙ ДЛЯ РОЗВИТКУ РИНКУ ЦІННИХ ПАПЕРІВ
Authors: Fufalko I. Yu.
Published: June 2017

Стаття присвячена дослідженню ролі фінансових інституцій, таких як банки, страхові компанії та інститути спільного інвестування, на фінансовому ринку України та Європейського Союзу, а також визначенню впливу кожного з них на ринок цінних паперів. Шляхом аналізу структури фінансових ринків України та ЄС було визначено, яку частку активів займає кожен вид фінансових інституцій. Це дозволило оцінити їх роль на відповідному фінансовому ринку в цілому, а напрями інвестування цих активів дозволили визначити їх внесок в розвиток власне ринку цінних паперів. В ході аналізу визначено, що значення банків для розвитку ринку цінних паперів в ЄС не є визначальним. Значну частку своїх активів у цінних паперах розміщують страхові компанії, пенсійні фонди та, так званий, альтернативний банківський сектор (в Україні – інститути спільного інвестування). Саме тому, пропорційний та паралельний розвиток усіх вищезгаданих видів фінансових інституцій  є необхідною передумовою розвитку ринку цінних паперів України.
ФІНАНСОВІ АСПЕКТИ ОРЕНДИ ЕКОЛОГІЧНО ЧИСТИХ ЗЕМЕЛЬ В КАРПАТСЬКОМУ МАКРОРЕГІОНІ
Authors: Sus. T.Yо.
Published: June 2017

Розглянуто особливості сучасного розвитку ринку оренди сільськогосподарських земель в Україні.. Запропоновано можливі два сценарії розвитку земельних відносин в умовах мораторію на продаж землі та фінансової кризи. Проаналізовано основні напрями розвитку земельних відносин та загрози фактичного продажу сільгоспугідь в обхід встановленого мораторію через правочин емфітевзису. Виходячи зі складних економічних умов в яких знаходиться Україна, девальвації національної валюти та зниження реальної орендної плати, зростання рівня бідності серед сільського населення, договори права емфітевзису будуть набувати все більшої популярності. Це створює загрозливі тенденції для організації легального квазіринку землі в умовах мораторію і в сучасних реаліях він набуває популярності серед великих агрохолдингів. Зростанню популярності емфітевзису сприяє той фактор, що власники земельних паїв мають можливість одержати більшу суму за землю зразу по заключенні договору, а не частинами протягом всього терміну оренди. Розглянуто  спонукаючі чинники такого сценарію розвитку земельних відносин та прогалини в правовому забезпеченні реформування аграрного сектору.

Окреслено фінансові проблеми оренди екологічно чистих земель та напрями їх вирішення.
АНАЛІЗ СТРАХОВИКІВ НА РИНКУ СТРАХУВАННЯ ЖИТТЯ В УКРАЇНІ
Authors: Melnichyk Yu.M.
Published: June 2017

Стаття присвячена аналізу ринку страхування життя в Україні. Метою дослідження є аналіз фінансового стану лідерів-страховиків з довгострокового страхування життя. У статті розглянуто показники діяльності страховиків, проаналізовано фінансовий стан компаній. Зроблено висновки щодо стану страховика на ринку страхування життя.

У дослідженні використано сукупність загальнонаукових і спеціальних  методів, які взаємопов’язані між собою та застосовувалися у роботі в логічному та послідовному зв’язку.

Зроблено висновки та запропоновано пропозиції щодо поліпшення фінансового стану страховиків з метою удосконалення страхування життя на сучасному страховому ринку України.
Characterizing the Pyrenophora teres f. maculata–Barley Interaction Using Pathogen Genetics
Authors: Carlsen Steven A , Neupane Anjan , Wyatt Nathan A , Richards Jonathan K , Faris Justin D , Xu Steven S , Brueggeman Robert S , Friesen Timothy L
Published: June 2017

Pyrenophora teres f. maculata is the cause of the foliar disease spot form net blotch (SFNB) on barley. To evaluate pathogen genetics underlying the P. teres f. maculata–barley interaction, we developed a 105-progeny population by crossing two globally diverse isolates, one from North Dakota and the other from Western Australia. Progeny were phenotyped on a set of four barley genotypes showing a differential reaction to the parental isolates, then genotyped using a restriction site-associated-genotype-by-sequencing (RAD-GBS) approach. Genetic maps were developed for use in quantitative trait locus (QTL) analysis to identify virulence-associated QTL. Six QTL were identified on five different linkage groups and individually accounted for 20–37% of the disease variation, with the number of significant QTL ranging from two to four for the barley genotypes evaluated. The data presented demonstrate the complexity of virulence involved in the P. teres f. maculata–barley pathosystem and begins to lay the foundation for understanding this important interaction.
Influence of sleep disturbance, fatigue, vitality on oral health and academic performance in Indian dental students
Authors: Asawa Kailash , Sen Nandini , Bhat Nagesh , Tak Mridula , Sultane Pratibha , Mandal Aritra
Published: June 2017

Background. Oral health and academic performance are important contributing factors for a student’s professional life. Countless factors affect both, among which sleep, vitality and fatigue are less explored areas that also have a strong impact.Objective. The objective of the study was to assess the association of sleep disturbances, fatigue and vitality with self reported oral health status, oral hygiene habits and academic performance of dental students of Udaipur.Methods. A descriptive cross-sectional study was conducted among undergraduate and postgraduate dental students of Udaipur. Self-administered structured questionnaire was used to assess the psychological factors, vitality, sleep quality, fatigue, self reported oral health status, habits and academic performance. Analysis of variance and stepwise multiple linear regression were utilized for statistical analysis with 95% confidence level and 5% level of significance. Results. Of the 230 participants, 180 (78.3%) were undergraduates and 50 (21.7%) were postgraduates. Among them, females showed higher scores in disturbed sleep index (2.69±2.14) as compared to males (2.45±1.91). Respondents who had “Poor” dental health, scored more in disturbed sleep index (3.15±1.64) and fatigue scale (20.00±4.88). Subjects who flossed “everyday”, were found to have good sleep and more energy (p=0.01) and those who assessed themselves as excellent students scored more in the Vitality Scale (p=0.01) and less in the Sleep index (p=0.01). Conclusion. The present study confirms that disturbed sleep, aliveness and fatigue, all are interlinked with each other and are imperative factors having the potential to alter the oral health status, habits and academics of dental students.
Cholestasis and Hepatic Iron Deposition in an Infant With Complex Glycerol Kinase Deficiency
Authors: Montoya-Williams Diana , Mowitz Meredith
Published: June 2017

We present a 6-week-old male infant with persistent hyperbilirubinemia, hypertriglyceridemia, elevated creatine kinase levels, and transaminitis since the second week of life. When he developed hyperkalemia, clinical suspicion was raised for adrenal insufficiency despite hemodynamic stability. A full endocrine workup revealed nearly absent adrenocorticotropic hormone. Coupled with his persistent hypertriglyceridemia (peak of 811 mg/dL) and elevated creatine kinase levels (>20 000 U/L), his corticotropin level lead to a clinical diagnosis of complex glycerol kinase deficiency (GKD), also known as Xp21 deletion syndrome. This complex disorder encompasses the phenotype of Duchenne muscular dystrophy, GKD, and congenital adrenal hypoplasia due to the deletion of 3 contiguous genetic loci on the X chromosome. Our case exemplifies the presentation of this disorder and highlights the important lesson of distinguishing between adrenal hypoplasia congenita and congenital adrenal hyperplasia, as well as the sometimes subtle presentation of adrenal insufficiency. To our knowledge, it is also the first reported case of complex GKD deficiency with the additional finding of hepatic iron deposition, which may indicate a potential area for exploration regarding the pathogenesis of liver injury and cholestasis seen in cortisol-related endocrinopathies.
Патоморфологічна характеристика коронавірусної інфекції в собак
Authors: Lisova V. , Dubinenko O.
Published: June 2017

The results of the study of the morphological features of pathological processes in organs and tissues of dogs with coronavirus infection. The study of cadavers (n = 3) dogs of different breeds and sex between the ages of 2 to 6 months, who died with diarrheal syndrome. Presence of coronavirus, without other assiociants, in these cases had previously been confirmed in the polymerase chain reaction analysis of fecal samples. At this stage, the main method of our study was mortem autopsy. At autopsy, which was carried out in partial evisceration, recorded and described the macroscopic changes identified in various tissues and organs of dead dogs and selected pathological material for subsequent histological examination. It is shown that the most pronounced lesions and typical change in all dead dogs fixed contact in the small intestine (jejunum and to the ileum) and the regional lymph nodes to it, as well as in the spleen. It is shown that the morphological manifestations of coronavirus infection in dogs following features are on the macroscopic level: the presence of exudative inflammation in the small intestine in the form serous-fibrinous jejuno-ileitis; hyperplasia and serous-hemorrhagic lymphadenitis mesenteric lymph nodes; multiple foci of hemorrhage of different character (spotted and striped) in the parenchyma of the spleen and serous membrane of the small intestine; dilatation of the right ventricle of the heart; cachexy and dehydration due to diarrheal syndrome. Also, non-specific, but constant morphological features, which arose as a result of circulatory disorders and heart failure were: passive venous congestion of the liver, kidney and pulmonary edema; degenerative processes in the liver. In one case, we identified morphological features characteristic of serous-inflammatory swelling of the pancreas and pathological changes in the myocardium that are typical of concentric hypertrophy of left ventricular heart. These pathological processes can be considered a complication that developed as a result of the underlying disease.
Патоморфологічна характеристика хламідіозу в котів
Authors: Lisova V. , Savchenko A.
Published: June 2017

The results of the study of the morphological features of pathological processes in organs and tissues of dead cats from chlamydial infection. A study of cadavers (n = 8), cats of different breeds aged from 3 to 6 years old, who lives with the laboratory methods have been diagnosed and identified the pathogen Chlamydia felis. According to historical data from sick animals were recorded various nature and degree of conjunctivitis and pronounced signs of a lesion of the respiratory tract (rhinitis, bronchitis, pneumonia). The main research method was mortem examination, during which the fixed and described the macroscopic changes in the affected organs and tissues. The autopsy was carried out partial evisceration, while selected pathological material for further histological studies. It is shown that the most pronounced damage and characteristic macroscopic changes all dead cats fixed contact in lung tissues and regional lymph nodes (mediastinal and bronchial), and in the spleen. Macroscopic picture of lungs affected varied somewhat depending on the degree of damage and stages of morphogenesis. In most cases (n = 6) lesions in the lungs looked like multiple well-defined lesions that are localized in all lobes of the lungs. Morphological manifestations of chlamydial infection in the investigated dead cats on the macroscopic level following features are: 1) productive inflammation in the lungs in a subtotal and total interstitial pneumonia and pulmonary fibrosis; 2) catarrhal bronchitis; 3) hyperplasia and serous lymphadenitis of the mediastinal and bronchial lymph nodes; 4) hyperplasia of lymphoid nodules of the spleen; 5) serous conjunctivitis. Also, a disease accompanied by nonspecific general pathological processes, such as: passive venous congestion of the liver and kidneys; degenerative changes in the liver; dilation of the right ventricle of the heart, which occurs as a complication of the underlying disease. While studies of other organs and tissues of dead animals we have not found any macroscopic changes.
Застосування екстракортикального остеосинтезу за діафізарних переломів кісток кінцівок у собак
Authors: Dmytriev V.S. , Khomyn N.M.
Published: June 2017

The article presents an analysis of research results of domestic and foreign veterinary scientists concerning different treatments for dogs fractures of extremities. The researchers recommend to apply both conservative and radical treatment of orthopedic diseases, consisting in the use of different types of stable functional osteosynthesis (intramedullary, extra cortical and perosseous), creating conditions for early functioning of the injured area and the process of bone regeneration in the area of the fracture. It was established advantages and disadvantages of extra cortical osteogenesis and the feasibility of its application for diaphyseal fractures of extremities fractures in dogs. So, preference of closed intramedullary osteosynthesis consist in insignificant soft tissue injury. The downside is that that operation is performed blindly; is possible the injury of main nerves by pin, blood vessels, bones cracking. It is widely used open intramedullary drawback – destruction of bone marrow, vessels, circulatory disorders around the metal; reoperation is required to remove the metal holder. Extra cortical method provides reliable fixation of debris, especially for complex comminuted fracture. The disadvantage is the trauma during the imposition and removal of plates, infection of wounds. Perosseous allows to treat fractures of various localization, limb elongation, eliminate axial deformation and defects in bone and soft tissue of any origin and location, particularly complicated by osteomyelitis. But for its application requires special expensive equipment. Therefore becomes important the improvement of radical methods of treatment of fractures in order to stimulate regenerative processes and elimination of complications in the postoperative period.
Електронно-мікроскопічна будова клітин слизової оболонки товстої кишки свиней у нормі
Authors: Lemishevskyi V.
Published: June 2017

Electron microscopic research of the cells mucous membrane of the colon of pigs 70-day old, showed that the epithelial cells have a cylindrical shape and are tightly connected to each other. On the apical surface of the cells are placed small, short, single microvilli. Cytoplasm of moderate electron density. Contains a moderate amount of ribosomes, as well as moderately developed structures of the Golgi complex and endoplasmic reticulum. Cell nuclei were located near the basal membrane, a rounded shape. Condensed chromatin is concentrated, both near of the nuclear shell and evenly throughout the entire area of the nucleoplasm. In the nuclear shell, small pores are seen. Enteroendocrine cells in the mucosa of the colon had a trapezoidal shape. Most of the apical site of cytoplasm of the cells occupied a different sizes osmiophilic granules of secretions, among which were viewed individual organelles. The nucleus is of a rounded shape, often with one electronically dense nucleolus. Endocrinocytes have a close connection with the fenestrated by the blood capillaries. The epithelial layer includes goblet cells that have a narrow base and a wide apical zone where the presence of secretory granules was noted. Nuclear envelope with multiple invaginations and a significant content of compact chromatin. On the apical surface of the cells there were single, elongated forms – microvilli. Absorption cells are high and narrow, on the apical surface of which there are short and rare microvilli. Osmiophil granules of secretion were noted in the cytoplasm of cells. These results demonstrate the normal electron structure of the cells of the mucous membrane of the large intestine of pigs, Which will be useful in cases when there will be a need to study the structure of the intestine when feeding an animal various feed supplements.
Вплив переробки неякісних ветпрепаратів та кормових добавок на стан довкілля
Authors: Vischur V. , Velychko V. , Gutyj B.
Published: June 2017

Considering the requirements of the European Union for the quality and safety of veterinary drugs, feed and fodder additives and contamination of the environment with waste production, topical issue is the waste of utilization veterinary products of not quality: veterinary drugs and feed additives. Conducted analysis of waste utilization methods of veterinary drugs, feed and fodder additives will help manufacturers of veterinary products to use such methods of destruction of defective raw materials and drugs, which increase the culture of production and promote the fight for the health of animals and poultry, and therefore are safe for human health, is practical and economically feasible, not causing the environmental damage, make it possible to destroy the waste to the extent of their education.
Діазинон. Основні аспекти біологічної дії, токсикологічні властивості та патоморфологія отруєнь
Authors: Tumanov V.
Published: June 2017

The article represents data on chemical properties and main aspects of the biological action of the diazinon - organophosphate pesticide that is widely used as a drug with marked acaricidal and insecticidal properties. Analyzed published data on metabolism, diazinon accumulation in various organs and systems, and ways of removing from the body. The article shows the median lethal dose (LD50) diazinon for various kinds of animals. The special features of the pathogenesis of poisoning, the main mechanism of action of toxic organophosphorus pesticides is the phosphorylation and inhibition of acetylcholinesterase, resulting in a marked accumulation of acetylcholine in the cholinergic synapses, excessive stimulation of nerves and muscles, disruption passage of nerve impulses. The article detailed the clinical signs of acute poisoning by organophosphate compounds. These data indicate that the effects on the body organophosphorus pesticides includes muscarinic effects (sialorrhea and excessive secretion of sweat glands, bronchorrhea, increased motility of the gastrointestinal tract, accompanied by spastic contractions of the intestinal wall, vomiting and gastroenteritis), nicotine action (miofibrillation, rigidity pectoral muscles, paralysis of respiratory muscles with the development of sudden hypoxemia) and central effects (arising from the impact of the central nervous system and are accompanied by violation of its function). The analysis pathmorphology of poisoning of the organophosphate pesticide. These data indicate that structural changes diazinon poisoning is less specific than clinical signs and characterized by: the development of the circulatory disorders (acute congestive hyperemia recorded and hemorrhage), the appearance of dystrophic and necrotic changes parenchymal elements of the brain and spinal cord, liver, kidneys and so on. Also recorded alterations changes ganglion cells and spinal cord autonomic ganglion, proliferation of glial cells, and for subacute and chronic poisoning – disintegration of the myelin and nerve fibers axial cylinder. Described diazinon influence on organs of the immune system and ability to induce endocrine disorders. There are published data on the potential mutagenic, carcinogenic and teratogenic effects of the diazinon. The range of problems researd structural changes by the origin and development of clinical evidence for the effect of different doses diazinon and certain aspects of forensic veterinary diagnostic poisoning mammals and birds of organophosphate pesticides.
Використання молекулярно-біологічних методів досліджень у прикладних галузях ветеринарних наук
Authors: Nazar B. , Murska S. , Gufrij D. , Gutyj B.
Published: June 2017

The article deals with the information on the use of small amounts of molecular research methods in applied fields of veterinary science. Is also considered the main approaches and directions in the sector work of molecular biological research GNIKI of veterinary medicines and feed additives. The objects of researches of molecular biology are specific macromolecule – especially proteins and nucleic acids, the simplest form of living – isolated cell nucleus, organelles of cells, chromosomes, viruses and bacteria. The use of gene technology to analyze food quality for people and feeding stuffs for animal is due to the need for sensitive, rapid and accurate method. Using the PCR method is common for indication and identification of the causative agents of food poisoning. Based on the PCR it was developed methods for analyzing the products, which were made for the use of transgenic microorganisms. The actual use of the PCR is the determination of clinical strains antibiotic resistance of infectious diseases, creating the possibility of quantifying results account to control the dynamics infectious process, the correct choice of treatment and evaluating the effectiveness of used medicines. An important direction of the application of DNA technology is to identify products obtained after using genetic engineering techniques. Thereby, by means of molecular biological research methods the sector of molecular biological studies can perform the following tasks: detection, identification and quantification of the content of genetically modified organisms; identification of plant species of animal protein in premixes, fodder additives and animal feed; conducting monitoring investigations the content of genetically modified organisms and ruminant DNA in premixes, feed additives and animal nutrition according to an annual monitoring plan of feed, feed additives and premixes; in the future diagnosing infectious (bacteria) and parasitic exciter in farm animals and determination of antibiotic resistance in clinical strains of infectious diseases.
Ambientalização do currículo no Brasil: levantamento de teses e dissertações entre 2011 e 2014
Authors: Ernst Frizzo Taís Cristine
Published: June 2017

Este artigo tem como objetivo contribuir com o estado de conhecimento de pesquisas sobre a ambientalização do currículo. As considerações feitas referem se ao levantamento de teses e dissertações que constaram nos bancos da CAPES e do IBICT entre 2011 e 2014. Observou-se que, na educação básica, as pesquisas buscaram compreender como o currículo se relacionava à temática ambiental nas práticas pedagógicas e nas percepções e representações dos atores da instituição. Muitos autores observaram a incorporação das questões ambientais na escola, mas verificaram a necessidade de refletir sobre a existência de uma disciplina de Educação Ambiental. Já as pesquisas realizadas na educação superior objetivaram conhecer disciplinas que abordavam a temática ambiental em diferentes cursos. Dessa forma, acredita-se que o estado do conhecimento pode contribuir nas futuras pesquisas sobre o tema, bem como nas ações de ambientalização nas escolas e nas universidades.
Tecnologias digitais na educação: possibilidades para o desenvolvimento da educação para a cidadania global
Authors: Dos Santos Pricila Kohls , Schwanke Camila , Weber Machado Karen Graziela
Published: June 2017

O presente estudo objetivou investigar as contribuições das tecnologias digitais para a educação para a cidadania global. Há um entendimento de que essa cidadania diz respeito a um pertencimento a uma comunidade mais ampla, à humanidade como um todo. Além de competências, habilidades e conhecimentos cognitivos, surge a necessidade de uma educação que contribua para a resolução de desafios globais, que promova o respeito mútuo. Nesse sentido, evidencia-se que as tecnologias digitais se fazem presente em nossas vidas e o uso das mesmas pode vir a contribuir significativamente no contexto educacional, de modo a facilitar e qualificar o processo de ensino e de aprendizagem, fomentando o desenvolvimento da educação para a cidadania global. Esta investigação se caracteriza como uma pesquisa qualitativa, para a coleta de dados, utilizou-se um questionário online, sendo que a análise dos dados está apoiada nos princípios da análise textual discursiva. Com este estudo, foi possível constatar que é importante que os docentes encontrem formas de integrar as tecnologias aos procedimentos metodológicos adequados para que os estudantes sintam-se motivados, tenham mais iniciativa, explorem novas possibilidades, oportunizando-os a construir os seus conhecimentos ao longo do processo educativo. Percebemos que, embora, em alguns casos, os participantes da pesquisa não afirmem que a tecnologia pode contribuir para o desenvolvimento da educação para cidadania global, em suas experiências foi possível evidenciar a presença de aspectos relacionados à promoção do pensamento crítico, da formação de valores, do diálogo, características estas preconizadas pela Pedagogia da Educação para Cidadania Global.