bluuebunny/crossref_metadata_2025 huggingface dataset:
Fabrication of a Nano-ZnO/Polyethylene/Wood-Fiber Composite with Enhanced Microwave Absorption and Photocatalytic Activity via a Facile Hot-Press Method
Authors: Dang Baokang , Chen Yipeng , Shen Xiaoping , Chen Bo , Sun Qingfeng , Jin Chunde
Published: November 2017

A polyethylene/wood-fiber composite loaded with nano-ZnO was prepared by a facile hot-press method and was used for the photocatalytic degradation of organic compounds as well as for microwave absorption. ZnO nanoparticles with an average size of 29 nm and polyethylene (PE) powders were dispersed on the wood fibers’ surface through a viscous cationic polyacrylamide (CPAM) solution. The reflection loss (RL) value of the resulting composite was −21 dB, with a thickness of 3.5 mm in the frequency of 17.17 GHz. The PE/ZnO/wood-fiber (PZW) composite exhibited superior photocatalytic activity (84% methyl orange degradation within 300 min) under UV light irradiation. ZnO nanoparticels (NPs) increased the storage modulus of the PZW composite, and the damping factor was transferred to the higher temperature region. The PZW composite exhibited the maximum flexural strength of 58 MPa and a modulus of elasticity (MOE) of 9625 MPa. Meanwhile, it also displayed dimensional stability (thickness swelling value of 9%).
Insight into the Mechanism of Action of Marine Cytotoxic Thiazinoquinones
Authors: Imperatore Concetta , Cimino Paola , Cebrián-Torrejón Gerardo , Persico Marco , Aiello Anna , Senese Maria , Fattorusso Caterina , Menna Marialuisa , Doménech-Carbó Antonio
Published: November 2017

The electrochemical response of four natural cytotoxic thiazinoquinones isolated from the Aplidium species was studied using conventional solution-phase and solid-state techniques, based on the voltammetry of immobilized particles methodology. The interaction with O2 and electrochemically generated reactive oxygen species (ROS) was electrochemically monitored. At the same time, a molecular modeling study including density functional theory (DFT) calculations was performed in order to analyze the conformational and electronic properties of the natural thiazinoquinones, as well as those of their reduced intermediates. The obtained electrochemical and computational results were analyzed and correlated to cytotoxic activity of these compounds, highlighting some features possibly related to their mechanism of action.
5-Alkylresorcinol Derivatives from the Bryozoan Schizomavella mamillata: Isolation, Synthesis, and Antioxidant Activity
Authors: Ortega María , Pantoja Juan , De los Reyes Carolina , Zubía Eva
Published: November 2017

The chemical study of the bryozoan Schizomavella mamillata has led to the isolation of six new 5-alkylresorcinol derivatives, schizols A–F (1–6), whose structures were established by spectrocospic means. Schizol A (1) exhibits a (E)-6-phenylnon-5-enyl moiety linked to the C-5 of a resorcinol ring, while in schizol B (2) the substituent at C-5 contains an unusual 1,2-dihydrocyclobutabenzene moiety. Schizols C (3) and D (4) have been characterized as the 1-sulfate derivatives of 1 and 2, respectively, and schizols E (5) and F (6) are the corresponding 1,3-disulfates. Schizol A (1) has been synthetized from 3,5-dimethoxybenzaldehyde through a sequence involving a Wittig reaction for the construction of the C-1′,C-2′ bond and a Julia–Kocienski olefination for the synthesis of the C-5′,C-6′ double bond. In the ABTS (2,2′-azinobis(3-ethylbenzothiazoline-6-sulphonic acid)) antioxidant assay, the natural compounds schizol A (1) and schizol B (2) showed higher radical scavenging activity than the Trolox standard.
Degradation of Polysaccharides from Grateloupia filicina and Their Antiviral Activity to Avian Leucosis Virus Subgroup J
Authors: Sun Yuhao , Chen Xiaolin , Cheng Ziqiang , Liu Song , Yu Huahua , Wang Xueqin , Li Pengcheng
Published: November 2017

In this study, polysaccharides from Grateloupia filicinia (GFP) were extracted and several low molecular weight (Mw) G. filicina polysaccharides (LGFPs) were prepared by the hydrogen peroxide (H2O2) oxidation method. Additionally, the effect of different experimental conditions on the degradation of GFP was determined. Results showed that the GFP degradation rate was positively related to H2O2 concentration and temperature, and negatively related to pH. Chemical analysis and Fourier transform infrared spectra (FT-IR) of GFP and LGFPs showed that the degradation caused a slight decrease of total sugar and sulfate content. However, there was no obvious change for monosaccharide contents. Then, the anti-ALV-J activity of GFP and LGFPs were determined in vitro. Results revealed that all of the samples could significantly inhibit ALV-J and lower Mw LGFPs exhibited a stronger suppression, and that the fraction LGFP-3 with Mw 8.7 kDa had the best effect. In addition, the reaction phase assays showed that the inhibition effect was mainly because of the blocking virus adsorption to host cells. Moreover, real-time PCR, western-blot, and IFA were further applied to evaluate the blocking effects of LGFP-3. Results showed that the gene relative expression and gp85 protein for LGFPS-3 groups were all reduced. Data from IFA showed that there was less virus infected cells for 1000 and 200 μg/mL LGFPS-3 groups when compared to virus control. Therefore, lower Mw polysaccharides from G. filicina might supply a good choice for ALV-J prevention and treatment.
An Enhanced Robust Control Algorithm Based on CNF and ISM for the MEMS Micromirror against Input Saturation and Disturbance
Authors: Tan Jiazheng , Sun Weijie , Yeow John
Published: November 2017

Input saturation is a widespread phenomenon in the field of instrumentation, and is harmful to performance and robustness. In this paper, a control design framework based on composite nonlinear feedback (CNF) and integral sliding mode (ISM) technique is proposed for a MEMS micromirror to improve its performance under input saturation. To make the framework more effective, some essential improvements are supplied. With the application of the proposed design framework, the micromirror under input saturation and time-varying disturbances can achieve precise positioning with satisfactory transient performance compared with the open-loop performance.
Design, Synthesis, and Evaluation of Novel Phenolic Acid/Dipeptide/Borneol Hybrids as Potent Angiotensin Converting Enzyme (ACE) Inhibitors with Anti-hypertension Activity
Authors: Sun Ying , Bai Yujun , He Xirui , Bai Yajun , Liu Pei , Zhao Zefeng , Chen Xufei , Zheng Xiaohui
Published: November 2017

Under the guidance of combination of traditional Chinese medicine chemistry (CTCMC), this study describes the preparation of a phenolic acid/dipeptide/borneol hybrid consisting of phenolic acid and a bornyl moiety connected to the dipeptide N-terminal and C-terminal respectively. It also evaluates their angiotensin converting enzyme (ACE) inhibitory and synergistic antihypertensive activities. Briefly, a series of novel phenolic acid/dipeptide/borneol hybrids were prepared and investigated for their ability to inhibit ACE. The influence of the phenolic acid and bornyl moiety on subsite selectivity is also demonstrated. Among all the new compounds, two compounds—7a and 7g—reveal good inhibition potency in in vitro ACE-inhibitory tests. Interestingly, favorable binding results in molecular docking studies also supported the in vitro results. Additionally, the bioassay showed that oral administration of the two compounds displayed high and long-lasting antihypertensive activity both in acute antihypertensive tests and in therapeutic antihypertensive tests by non-invasive blood pressure measurements in spontaneously hypertensive rats.
1H-NMR-Based Metabonomics of the Protective Effect of Coptis chinensis and Berberine on Cinnabar-Induced Hepatotoxicity and Nephrotoxicity in Rats
Authors: Su Guangyue , Wang Haifeng , Gao Yuxian , Chen Gang , Pei Yuehu , Bai Jiao
Published: November 2017

Coptis chinensis Franch has been used in Traditional Chinese Medicine (TCM) for treating infectious and inflammatory diseases for over two thousand years. Berberine (BN), an isoquinoline alkaloid, is the main component of Coptis chinensis. The pharmacological basis for its therapeutic effects, which include hepatoprotective effects on liver injuries, has been studied intensively, yet the therapy of liver injuries and underlying mechanism remain unclear. We investigated the detoxification mechanism of Coptis chinensis and berberine using metabolomics of urine and serum in the present study. After the treatment with Coptis chinensis and berberine, compared with the cinnabar group, Coptis chinensis and berberine can regulate the concentration of the endogenous metabolites. PLS-DA score plots demonstrated that the urine and serum metabolic profiles in rats of the Coptis chinensis and berberine groups were similar those of the control group, yet remarkably apart from the cinnabar group. The mechanism may be related to the endogenous metabolites including energy metabolism, amino acid metabolism and metabolism of intestinal flora in rats. Meanwhile, liver and kidney histopathology examinations and serum clinical chemistry analysis verified the experimental results of metabonomics.
Anti-Inflammatory Effect of Malva sylvestris, Sida cordifolia, and Pelargonium graveolens Is Related to Inhibition of Prostanoid Production
Authors: Martins Cleverson , Campos Michel , Irioda Ana , Stremel Dile , Trindade Angela , Pontarolo Roberto
Published: November 2017

The ability of plant extracts and preparations to reduce inflammation has been proven by different means in experimental models. Since inflammation enhances the release of specific mediators, inhibition of their production can be used to investigate the anti-inflammatory effect of plants widely used in folk medicine for this purpose. The study was performed for leaves and flowers of Malva sylvestris, and leaves of Sida cordifolia and Pelargonium graveolens. These are three plant species known in Brazil as Malva. The anti-inflammatory activity of extracts and fractions (hexane, chloroform, ethyl acetate, and residual) was evaluated by quantitation of prostaglandins (PG) PGE2, PGD2, PGF2α, and thromboxane B2 (the stable nonenzymatic product of TXA2) concentration in the supernatant of lipopolysaccharide (LPS)- induced RAW 264.7 cells. Inhibition of anti-inflammatory mediator release was observed for plants mainly in the crude extract, ethyl acetate fraction, and residual fraction. The results suggest superior activity of S. cordifolia, leading to significantly lower values of all mediators after treatment with its residual fraction, even at the lower concentration tested (10 μg/mL). M. sylvestris and P. graveolens showed similar results, such as the reduction of all mediators after treatment, with leaf crude extracts (50 μg/mL). These results suggest that the three species known as Malva have anti-inflammatory properties, S. cordifolia being the most potent.
A Rapid and Simple TLC-Densitometric Method for Assay of Clobetasol Propionate in Topical Solution
Authors: Dolowy Malgorzata , Kozik Violetta , Bak Andrzej , Jampilek Josef , Barbusinski Krzysztof , Thomas Maciej , Pyka-Pajak Alina
Published: November 2017

A rapid, simple to use and low-cost thin-layer chromatographic procedure in normal phase system with densitometric detection at 246 nm was carefully validated according to the International Conference on Harmonisation (ICH) guidelines for assay of clobetasol propionate in topical solution containing clobetasol propionate in quantity 0.50 mg/mL. The adopted thin-layer chromatographic (TLC)-densitometric procedure could effectively separate clobetasol propionate from its related compound, namely clobetasol. It is linear for clobetasol propionate in the range of 0.188 ÷ 5 µg/spot. The limit of detection (LOD) and limit of quantification (LOQ) value is 0.061 and 0.186 µg/spot, respectively. Accuracy of proposed procedure was evaluated by recovery test. The mean recovery of studied clobetasol propionate ranges from 98.7 to 101.0%. The coefficient of variation (CV, %) obtained during intra-day and inter-day studies, which was less than 2% (0.40 ÷ 1.17%), confirms the precision of described method. The assay value of clobetasol propionate is consistent with the pharmacopoeial requirements. In conclusion, it can be suitable as a simple and economic procedure for routine quality control laboratories of clobetasol propionate in topical solution.
Microwave-Assisted Extraction of Cannabinoids in Hemp Nut Using Response Surface Methodology: Optimization and Comparative Study
Authors: Chang Chih-Wei , Yen Ching-Chi , Wu Ming-Tsang , Hsu Mei-Chich , Wu Yu-Tse
Published: November 2017

Hemp nut is commonly incorporated into several food preparations; however, most countries set regulations for hemp products according to their cannabinoid content. In this study, we have developed an efficient microwave-assisted extraction (MAE) method for cannabinoids (i.e., Δ9-tetrahydrocannabinol, cannabidiol, and cannabinol) in hemp nut. Optimization of the MAE procedure was conducted through single factor experiments and response surface methodology (RSM). A comparative study was also conducted to determine the differences in the extraction yields and morphology of hemp nut between MAE and reference extraction methods, namely heat reflux extraction (HRE), Soxhlet extraction (SE), supercritical fluid extraction (SFE), and ultrasound-assisted extraction (UAE). Among the independent variables in RSM, the temperature was the most significant parameter. The optimal conditions of MAE were as follows: extraction solvent of methanol, microwave power of 375 W, temperature of 109 °C, and extraction time of 30 min. Compared with reference extraction methods, MAE achieved the highest extraction yields of total cannabinoids in hemp nut (6.09 μg/g for MAE; 4.15 μg/g for HRE; 5.81 μg/g for SE; 3.61 μg/g for SFE; 3.73 μg/g for UAE) with the least solvent consumption and shortest time. Morphological observations showed that substantial cell rupturing occurred in the microstructure of hemp nut after MAE, indicating enhanced dissolution of the target compounds during the extraction process. The MAE method is thus a rapid, economic, and environmentally friendly extraction method that is both effective and practical for industrial applications.
Sol-Gel-Synthesis of Nanoscopic Complex Metal Fluorides
Authors: Rehmer Alexander , Scheurell Kerstin , Scholz Gudrun , Kemnitz Erhard
Published: November 2017

The fluorolytic sol-gel synthesis for binary metal fluorides (AlF3, CaF2, MgF2) has been extended to ternary and quaternary alkaline earth metal fluorides (CaAlF5, Ca2AlF7, LiMgAlF6). The formation and crystallization of nanoscopic ternary CaAlF5 and Ca2AlF7 sols in ethanol were studied by 19F liquid and solid state NMR (nuclear magnetic resonance) spectroscopy, as well as transmission electron microscopy (TEM). The crystalline phases of the annealed CaAlF5, Ca2AlF7, and LiMgAlF6 xerogels between 500 and 700 °C could be determined by X-ray powder diffraction (XRD) and 19F solid state NMR spectroscopy. The thermal behavior of un-annealed nanoscopic ternary and quaternary metal fluoride xerogels was ascertained by thermal analysis (TG/DTA). The obtained crystalline phases of CaAlF5 and Ca2AlF7 derived from non-aqueous sol-gel process were compared to crystalline phases from the literature. The corresponding nanoscopic complex metal fluoride could provide a new approach in ceramic and luminescence applications.
Solvothermal Synthesis of a Hollow Micro-Sphere LiFePO4/C Composite with a Porous Interior Structure as a Cathode Material for Lithium Ion Batteries
Authors: Liu Yang , Zhang Jieyu , Li Ying , Hu Yemin , Li Wenxian , Zhu Mingyuan , Hu Pengfei , Chou Shulei , Wang Guoxiu
Published: November 2017

To overcome the low lithium ion diffusion and slow electron transfer, a hollow micro sphere LiFePO4/C cathode material with a porous interior structure was synthesized via a solvothermal method by using ethylene glycol (EG) as the solvent medium and cetyltrimethylammonium bromide (CTAB) as the surfactant. In this strategy, the EG solvent inhibits the growth of the crystals and the CTAB surfactant boots the self-assembly of the primary nanoparticles to form hollow spheres. The resultant carbon-coat LiFePO4/C hollow micro-spheres have a ~300 nm thick shell/wall consisting of aggregated nanoparticles and a porous interior. When used as materials for lithium-ion batteries, the hollow micro spherical LiFePO4/C composite exhibits superior discharge capacity (163 mAh g−1 at 0.1 C), good high-rate discharge capacity (118 mAh g−1 at 10 C), and fine cycling stability (99.2% after 200 cycles at 0.1 C). The good electrochemical performances are attributed to a high rate of ionic/electronic conduction and the high structural stability arising from the nanosized primary particles and the micro-sized hollow spherical structure.
Dietary Intake after Weight Loss and the Risk of Weight Regain: Macronutrient Composition and Inflammatory Properties of the Diet
Authors: Muhammad Harry , Vink Roel , Roumans Nadia , Arkenbosch Laura , Mariman Edwin , Van Baak Marleen
Published: November 2017

Weight regain after successful weight loss is a big problem in obesity management. This study aimed to investigate whether weight regain after a weight loss period is correlated with the macronutrient composition and/or the inflammatory index of the diet during that period. Sixty one overweight and obese adults participated in this experimental study. Subjects lost approximately 10% of their initial weight by means of very low-calorie diet for five weeks, or a low calorie diet for 12 weeks. After that, subjects in both groups followed a strict weight maintenance diet based on individual needs for four weeks, which was followed by a nine-month weight maintenance period without dietary counseling. Anthropometrics and dietary intake data were recorded before weight loss (baseline) and during the weight maintenance period. On average, participants regained approximately half of their lost weight. We found no evidence that macronutrient composition during the weight maintenance period was associated with weight regain. The dietary inflammatory index (r = 0.304, p = 0.032) was positively correlated with weight regain and remained significant after correction for physical activity (r = 0.287, p = 0.045). Our data suggest that the inflammatory properties of diet play a role in weight regain after weight loss in overweight and obese adults.
Association between Duration of Folic Acid Supplementation during Pregnancy and Risk of Postpartum Depression
Authors: Yan Jing , Liu Yuyan , Cao Lujia , Zheng Yuzhi , Li Wen , Huang Guowei
Published: November 2017

Postpartum depression (PPD), as a common complication of childbearing, could have adverse consequences on mothers, children, and families. This cohort study aimed to assess the association between duration of folic acid (FA) supplementation during pregnancy and the onset of PPD in Chinese women. A total of 1592 participants were recruited, and data collected between July 2015 and March 2017 in Tianjin, China. Participants’ baseline data were collected regarding socio-demographic and lifestyle characteristics, obstetric history, and FA supplementation during pregnancy. The Chinese version of the self-rating depression scale was used to assess depressive symptoms at 6–12 weeks postpartum, and the prevalence of PPD in participants was 29.4%. Pregnant women who took FA supplements for >6 months had a lower prevalence of PPD, compared to those who took FA for ≤6 months. After using the 1:1 ratio propensity score matching, 601 FA-users ≤ 6 months and 601 FA-users > 6 months were included in the further analyses; this also yielded similar results (P < 0.05). Logistic regression analysis showed that FA intake for >6 months was an independent determinant of PPD (odds ratio = 0.76; 95% confidence interval: 0.59–0.98; P < 0.05). Thus, prolonged FA supplementation during pregnancy was associated with a decreased risk of PPD in Chinese women.
What Should Be Taught in Secondary Schools’ Nutrition and Food Systems Education? Views from Prominent Food-Related Professionals in Australia
Authors: Sadegholvad Sanaz , Yeatman Heather , Parrish Anne-Maree , Worsley Anthony
Published: November 2017

Education can help young people to attain the knowledge and the skills that they need to make proper food choices and develop lifelong healthy eating patterns. This study explored the perspectives of prominent food-related professionals in Australia regarding essential nutrition and food systems (N&FS) education programs for adolescents during formal education. Semi-structured interviews were conducted with 21 prominent food-related professionals in Australia. Interview transcripts were analysed thematically. Four essential areas for N&FS education programs were identified. (1) Key nutrition messages to a healthy lifestyle; (2) Skill development programs to enhance health and wellbeing; (3) Ethical food-related lessons to support environmental sustainability, farm animal welfare, local producers, and food security; and, (4) Introductory lessons about foods from farm to plate to facilitate more informed food choices. Findings of this study may provide new insights for curriculum developers in Australia for further assessment of the current gaps in N&FS components of secondary school curriculum. Integration of these four areas into secondary school curricula has the potential to enhance adolescents’ knowledge of important scientific and ethical issues in a range of N&FS fields, and enable them to develop fundamental food-related life skills that are supportive of health and wellbeing.
Symptom Severity Following Rifaximin and the Probiotic VSL#3 in Patients with Chronic Pelvic Pain Syndrome (Due to Inflammatory Prostatitis) Plus Irritable Bowel Syndrome
Authors: Vicari Enzo , Salemi Michele , Sidoti Giuseppe , Malaguarnera Mariano , Castiglione Roberto
Published: November 2017

This study investigated the effects of long-term treatment with rifaximin and the probiotic VSL#3 on uro-genital and gastrointestinal symptoms in patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) plus diarrhoea-predominant irritable bowel syndrome (D-IBS) compared with patients with D-IBS alone. Eighty-five patients with CP/CPPS (45 with subtype IIIa and 40 with IIIb) plus D-IBS according to the Rome III criteria and an aged-matched control-group of patients with D-IBS alone (n = 75) received rifaximin and VSL#3. The primary endpoints were the response rates of IBS and CP/CPPS symptoms, assessed respectively through Irritable Bowel Syndrome Severity Scoring System (IBS-SSS) and The National Institute of Health Chronic Prostatitis Symptom Index (NIH-CPSI), and performed at the start of therapy (V0) and three months after (V3). In IIIa prostatitis patients, the total NIH-CPSI scores significantly (p < 0.05) decreased from a baseline mean value of 21.2 to 14.5 at V3 , as did all subscales, and in the IIIb the total NIH-CPSI score also significantly decreased (from 17.4 to 15.1). Patients with IBS alone showed no significant differences in NIH-CPSI score. At V3, significantly greater improvement in the IBS-SSS and responder rate were found in IIIa patients. Our results were explained through a better individual response at V3 in IIIa prostatitis of urinary and gastrointestinal symptoms, while mean leukocyte counts on expressed prostate secretion (EPS) after prostate massage significantly lowered only in IIIa cases.
Self-Emulsifying Granules and Pellets: Composition and Formation Mechanisms for Instant or Controlled Release
Authors: Nikolakakis Ioannis , Partheniadis Ioannis
Published: November 2017

Many articles have been published in the last two decades demonstrating improvement in the dissolution and absorption of low solubility drugs when formulated into self-emulsifying drug delivery systems (SEDDS). Several such pharmaceutical products have appeared in the market for medium dose (Neoral® for Cyclsoprin A, Kaletra® for Lopinavir and Ritonavir), or low dose medications (Rocaltrol® for Calcitriol and Avodart® for Dutasteride). However, these are in the form of viscous liquids or semisolid presentations, characterized by the disadvantages of high production cost, stability problems and the requirement of large quantities of surfactants. Solid SEDDS (S-SEDDS), as coarse powders, granules or pellets, besides solubility improvement, can be filled easily into capsules or processed into tablets providing a handy dosage form with instant release, which can be further developed into controlled release by mixing with suitable polymers or coating with polymeric films. In this review, the materials used for the preparation of S-SEDDS, their properties and role in the formulations are detailed. Factors affecting the physical characteristics, mechanical properties of S-SEDDS as well as their in vitro release and in vivo absorption are discussed. The mechanisms involved in the formation of instant and sustained release self-emulsifying granules or pellets are elucidated. Relationships are demonstrated between the characteristics of S-SEDDS units (size, shape, mechanical properties, re-emulsification ability, drug migration and drug release) and the properties of the submicron emulsions used as massing liquids, with the aim to further elucidate the formation mechanisms. The influence of the composition of the powdered ingredients forming the granule or pellet on the properties of S-SEDDS is also examined. Examples of formulations of S-SEDDS that have been reported in the literature in the last thirteen years (2004–2017) are presented.
The Effect of Donor and Nonfullerene Acceptor Inhomogeneous Distribution within the Photoactive Layer on the Performance of Polymer Solar Cells with Different Device Structures
Authors: Wang Yaping , Shi Zhenzhen , Liu Hao , Wang Fuzhi , Bai Yiming , Bian Xingming , Zhang Bing , Hayat Tasawar , Alsaedi Ahmed , Tan Zhan’ao
Published: November 2017

Due to the inhomogeneous distribution of donor and acceptor materials within the photoactive layer of bulk heterojunction organic solar cells (OSCs), proper selection of a conventional or an inverted device structure is crucial for effective exciton dissociation and charge transportation. Herein, we investigate the donor and acceptor distribution within the non-fullerene photoactive layer based on PBDTTT-ET:IEICO by time-of-flight secondary-ion mass spectroscopy (TOF-SIMS) and scanning Kelvin probe microscopy (SKPM), indicating that more IEICO enriches on the surface of the photoactive layer while PBDTTT-ET distributes homogeneously within the photoactive layer. To further understand the effect of the inhomogeneous component distribution on the photovoltaic performance, both conventional and inverted OSCs were fabricated. As a result, the conventional device shows a power conversion efficiency (PCE) of 8.83% which is 41% higher than that of inverted one (6.26%). Eventually, we employed nickel oxide (NiOx) instead of PEDOT:PSS as anode buffer layer to further enhance the stability and PCE of OSCs with conventional structure, and a promising PCE of 9.12% is achieved.
Shape Memory Polymers Containing Higher Acrylate Content Display Increased Endothelial Cell Attachment
Authors: Govindarajan Tina , Shandas Robin
Published: November 2017

Shape Memory Polymers (SMPs) are smart materials that can recall their shape upon the application of a stimulus, which makes them appealing materials for a variety of applications, especially in biomedical devices. Most prior SMP research has focused on tuning bulk properties; studying surface effects of SMPs may extend the use of these materials to blood-contacting applications, such as cardiovascular stents, where surfaces that support rapid endothelialization have been correlated to stent success. Here, we evaluate endothelial attachment onto the surfaces of a family of SMPs previously developed in our group that have shown promise for biomedical devices. Nine SMP formulations containing varying amounts of tert-Butyl acrylate (tBA) and Poly(ethylene glycol) dimethacrylate (PEGDMA) were analyzed for endothelial cell attachment. Dynamic mechanical analysis (DMA), contact angle studies, and atomic force microscopy (AFM) were used to verify bulk and surface properties of the SMPs. Human umbilical vein endothelial cell (HUVEC) attachment and viability was verified using fluorescent methods. Endothelial cells preferentially attached to SMPs with higher tBA content, which have rougher, more hydrophobic surfaces. HUVECs also displayed an increased metabolic activity on these high tBA SMPs over the course of the study. This class of SMPs may be promising candidates for next generation blood-contacting devices.
Ultra-Broadband THz Antireflective Coating with Polymer Composites
Authors: Cai Bin , Chen Haitao , Xu Gongjie , Zhao Hongwei , Sugihara Okihiro
Published: November 2017

Achieving an ultra-broadband range is an essential development direction in terahertz techniques; however, a method to cover the full terahertz band by using a highly efficient antireflection (AR) coating that could greatly increase the efficiency of terahertz radiation is still lacking. It is known that structures possessing a graded-index profile can offer a broadband AR effect, and such structures have been widely used, especially in the visible range. In this paper, first, we tuned the refractive index of a cyclo-olefin polymer (COP) by using a TiO2 dopant, and a polymer–TiO2 composite with a refractive index of 3.1 was achieved. We then fabricated a surface-relief structure with a graded-index profile by using a hot-embossing method. The structure on the silicon substrate can provide an excellent AR effect, but the working band is still limited by its scale of sag and swell. To obtain an ultra-broadband AR effect, we then proposed a flat six-layer structure; a graded-index profile was obtained by casting epoxy–TiO2 composites in the order of a high index to lower indices. With a very well controlled refractive index and thickness of each layer, we achieved an AR effect of <2% in the ultra-broadband of 0.2–20 THz.
Urban Residents’ Religious Beliefs and Influencing Factors on Christianity in Wuhan, China
Authors: Han Junqiang , Meng Yingying , Xu Chengcheng , Qin Siqi
Published: November 2017

In this paper, we conducted an empirical analysis of the reasons for belief in Christianity in Wuhan, China. The data in this paper is from Chinese Urban Research Center for Ethnic and Religious Affairs Management, collected in 2015. We focus on the group characteristics of Christians in urban areas, and its influencing factors. It is found that the Christians in Wuhan are typically older, female, and less educated. Other patterns we have found include powerful influence by family members and friends, pragmatic reasons for following Christianity, family parties as a common way of religious assembly, and discretional admission and exit. Logistic regression is employed here to analyze the determinants of Christian belief. Gender, age, marital status, average annual income, education degree, and health conditions have significant effects on believing in Christianity.
Detection of Irrigated Crops from Sentinel-1 and Sentinel-2 Data to Estimate Seasonal Groundwater Use in South India
Authors: Ferrant Sylvain , Selles Adrien , Le Page Michel , Herrault Pierre-Alexis , Pelletier Charlotte , Al-Bitar Ahmad , Mermoz Stéphane , Gascoin Simon , Bouvet Alexandre , Saqalli Mehdi , Dewandel Benoit , Caballero Yvan , Ahmed Shakeel , Maréchal Jean-Christophe , Kerr Yann
Published: November 2017

Indian agriculture relies on monsoon rainfall and irrigation from surface and groundwater. The interannual variability of monsoon rainfalls is high, which forces South Indian farmers to adapt their irrigated areas to local water availability. In this study, we have developed and tested a methodology for monitoring these spatiotemporal variations using Sentinel-1 and -2 observations over the Kudaliar catchment, Telangana State (~1000 km2). These free radar and optical data have been acquired since 2015 on a weekly basis over continental areas, at a high spatial resolution (10–20 m) that is well adapted to the small areas of South Indian field crops. A machine learning algorithm, the Random Forest method, was used over three growing seasons (January to March and July to November 2016 and January to March 2017) to classify small patches of inundated rice paddy, maize, and other irrigated crops, as well as surface water stored in the small reservoirs scattered across the landscape. The crop production comprises only irrigated crops (less than 20% of the areas) during the dry season (Rabi, December to March), to which rain-fed cotton is added to reach 60% of the areas during the monsoon season (Kharif, June to November). Sentinel-1 radar backscatter provides useful observations during the cloudy monsoon season. The lowest irrigated area totals were found during Rabi 2016 and Kharif 2016, accounting for 3.5 and 5% with moderate classification confusion. This confusion decreases with increasing areas of irrigated crops during Rabi 2017. During this season, 16% of rice and 6% of irrigated crops were detected after the exceptional rainfalls observed in September. Surface water in small surface reservoirs reached 3% of the total area, which corresponds to a high value. The use of both Sentinel datasets improves the method accuracy and strengthens our confidence in the resulting maps. This methodology shows the potential of automatically monitoring, in near real time, the high short term variability of irrigated area totals in South India, as a proxy for estimating irrigated water and groundwater needs. These are estimated over the study period to range from 49.5 ± 0.78 mm (1.5% uncertainty) in Rabi 2016, and 44.9 ± 2.9 mm (6.5% uncertainty) in the Kharif season, to 226.2 ± 5.8 mm (2.5% uncertainty) in Rabi 2017. This variation must be related to groundwater recharge estimates that range from 10 mm to 160 mm·yr−1 in the Hyderabad region. These dynamic agro-hydrological variables estimated from Sentinel remote sensing data are crucial in calibrating runoff, aquifer recharge, water use and evapotranspiration for the spatially distributed agro-hydrological models employed to quantify the impacts of agriculture on water resources.
Concept and Evaluation of a New Piezoelectric Transducer for an Implantable Middle Ear Hearing Device
Authors: Liu Houguang , Cheng Jinlei , Yang Jianhua , Rao Zhushi , Cheng Gang , Yang Shanguo , Huang Xinsheng , Wang Mengli
Published: November 2017

Implantable middle ear hearing devices (IMEHDs) have been developed as a new technology to overcome the limitations of conventional hearing aids. The piezoelectric cantilever transducers currently used in the IMEHDs have the advantages of low power consumption and ease of fabrication, but generate less high-frequency output. To address this problem, we proposed and designed a new piezoelectric transducer based on a piezoelectric stack for the IMEHD. This new transducer, attached to the incus body with a coupling rod, stimulates the ossicular chain in response to the expansion-and-contraction of its piezoelectric stack. To test its feasibility for hearing loss compensation, a bench testing of the transducer prototype and a temporal bone experiment were conducted, respectively. Bench testing results showed that the new transducer did have a broad frequency bandwidth. Besides, the transducer was found to have a low total harmonic distortion (<0.75%) in all frequencies, and small release time (1 ms). The temporal bone experiment further proved that the transducer has the capability to produce sufficient vibrations to compensate for severe sensorineural hearing loss, especially at high frequencies. This property benefits the treatment of the most common sloping high-frequency sensorineural hearing loss. To produce a 100 dB SPL equivalent sound pressure at 1 kHz, its power consumption is 0.49 mW, which is low enough for the transducer to be utilized in the IMEHD.
Experimental Investigation of the Piezoresistive Properties of Cement Composites with Hybrid Carbon Fibers and Nanotubes
Authors: Lee Seung-Jung , You Ilhwan , Zi Goangseup , Yoo Doo-Yeol
Published: November 2017

Cement-based sensors with hybrid conductive fillers using both carbon fibers (CFs) and multi-walled carbon nanotubes (MWCNTs) were experimentally investigated in this study. The self-sensing capacities of cement-based composites with only CFs or MWCNTs were found based on preliminary tests. The results showed that the percolation thresholds of CFs and MWCNTs were 0.5–1.0 vol.% and 1.0 vol.%, respectively. Based on these results, the feasibility of self-sensing composites with four different amounts of CFs and MWCNTs was considered under cyclic compression loads. When the amount of incorporated CFs increased and the amount of incorporated MWCNTs decreased, the self-sensing capacity of the composites was reduced. It was concluded that cement-based composites containing both 0.1 vol.% CFs and 0.5 vol.% MWCNTs could be an alternative to cement-based composites with 1.0 vol.% MWCNTs in order to achieve equivalent self-sensing performance at half the price. The gauge factor (GF) for that composite was 160.3 with an R-square of 0.9274 in loading stages I and II, which was similar to the GF of 166.6 for the composite with 1.0 vol.% MWCNTs.
Local Positioning System Using Flickering Infrared LEDs
Authors: Raharijaona Thibaut , Mawonou Rodolphe , Nguyen Thanh , Colonnier Fabien , Boyron Marc , Diperi Julien , Viollet Stéphane
Published: November 2017

A minimalistic optical sensing device for the indoor localization is proposed to estimate the relative position between the sensor and active markers using amplitude modulated infrared light. The innovative insect-based sensor can measure azimuth and elevation angles with respect to two small and cheap active infrared light emitting diodes (LEDs) flickering at two different frequencies. In comparison to a previous lensless visual sensor that we proposed for proximal localization (less than 30 cm), we implemented: (i) a minimalistic sensor in terms of small size (10 cm 3 ), light weight (6 g) and low power consumption (0.4 W); (ii) an Arduino-compatible demodulator for fast analog signal processing requiring low computational resources; and (iii) an indoor positioning system for a mobile robotic application. Our results confirmed that the proposed sensor was able to estimate the position at a distance of 2 m with an accuracy as small as 2-cm at a sampling frequency of 100 Hz. Our sensor can be also suitable to be implemented in a position feedback loop for indoor robotic applications in GPS-denied environment.
A Simple Assay for Ultrasensitive Colorimetric Detection of Ag+ at Picomolar Levels Using Platinum Nanoparticles
Authors: Wang Yi-Wei , Wang Meili , Wang Lixing , Xu Hui , Tang Shurong , Yang Huang-Hao , Zhang Lan , Song Hongbo
Published: November 2017

In this work, uniformly-dispersed platinum nanoparticles (PtNPs) were synthesized by a simple chemical reduction method, in which citric acid and sodium borohydride acted as a stabilizer and reducer, respectively. An ultrasensitive colorimetric sensor for the facile and rapid detection of Ag+ ions was constructed based on the peroxidase mimetic activities of the obtained PtNPs, which can catalyze the oxidation of 3,3’,5,5’-tetramethylbenzidine (TMB) by H2O2 to produce colored products. The introduced Ag+ would be reduced to Ag0 by the capped citric acid, and the deposition of Ag0 on the PtNPs surface, can effectively inhibit the peroxidase-mimetic activity of PtNPs. Through measuring the maximum absorption signal of oxidized TMB at 652 nm, ultra-low detection limits (7.8 pM) of Ag+ can be reached. In addition to such high sensitivity, the colorimetric assay also displays excellent selectivity for other ions of interest and shows great potential for the detection of Ag+ in real water samples.
Indoor Multipath Assisted Angle of Arrival Localization
Authors: Wielandt Stijn , Strycker Lieven
Published: November 2017

Indoor radio frequency positioning systems enable a broad range of location aware applications. However, the localization accuracy is often impaired by Non-Line-Of-Sight (NLOS) connections and indoor multipath effects. An interesting evolution in widely deployed communication systems is the transition to multi-antenna devices with beamforming capabilities. These properties form an opportunity for localization methods based on Angle of Arrival (AoA) estimation. This work investigates how multipath propagation can be exploited to enhance the accuracy of AoA localization systems. The presented multipath assisted method resembles a fingerprinting approach, matching an AoA measurement vector to a set of reference vectors. However, reference data is not generated by labor intensive site surveying. Instead, a ray tracer is used, relying on a-priori known floor plan information. The resulting algorithm requires only one fixed receiving antenna array to determine the position of a mobile transmitter in a room. The approach is experimentally evaluated in LOS and NLOS conditions, providing insights in the accuracy and robustness. The measurements are performed in various indoor environments with different hardware configurations. This leads to the conclusion that the proposed system yields a considerable accuracy improvement over common narrowband AoA positioning methods, as well as a reduction of setup efforts in comparison to conventional fingerprinting systems.
Design and Analysis of a Data Fusion Scheme in Mobile Wireless Sensor Networks Based on Multi-Protocol Mobile Agents
Authors: Wu Chunxue , Wu Wenliang , Wan Caihua , Bekkering Ernst , Xiong Naixue
Published: November 2017

Sensors are increasingly used in mobile environments with wireless network connections. Multiple sensor types measure distinct aspects of the same event. Their measurements are then combined to produce integrated, reliable results. As the number of sensors in networks increases, low energy requirements and changing network connections complicate event detection and measurement. We present a data fusion scheme for use in mobile wireless sensor networks with high energy efficiency and low network delays, that still produces reliable results. In the first phase, we used a network simulation where mobile agents dynamically select the next hop migration node based on the stability parameter of the link, and perform the data fusion at the migration node. Agents use the fusion results to decide if it should return the fusion results to the processing center or continue to collect more data. In the second phase. The feasibility of data fusion at the node level is confirmed by an experimental design where fused data from color sensors show near-identical results to actual physical temperatures. These results are potentially important for new large-scale sensor network applications.
Towards the Development of a Low-Cost Device for the Detection of Explosives Vapors by Fluorescence Quenching of Conjugated Polymers in Solid Matrices
Authors: Martelo Liliana , Das Neves Tiago , Figueiredo João , Marques Lino , Fedorov Alexander , Charas Ana , Berberan-Santos Mário , Burrows Hugh
Published: November 2017

Conjugated polymers (CPs) have proved to be promising chemosensory materials for detecting nitroaromatic explosives vapors, as they quickly convert a chemical interaction into an easily-measured high-sensitivity optical output. The nitroaromatic analytes are strongly electron-deficient, whereas the conjugated polymer sensing materials are electron-rich. As a result, the photoexcitation of the CP is followed by electron transfer to the nitroaromatic analyte, resulting in a quenching of the light-emission from the conjugated polymer. The best CP in our studies was found to be poly[(9,9-dioctylfluorenyl-2,7-diyl)-co-bithiophene] (F8T2). It is photostable, has a good absorption between 400 and 450 nm, and a strong and structured fluorescence around 550 nm. Our studies indicate up to 96% quenching of light-emission, accompanied by a marked decrease in the fluorescence lifetime, upon exposure of the films of F8T2 in ethyl cellulose to nitrobenzene (NB) and 1,3-dinitrobenzene (DNB) vapors at room temperature. The effects of the polymeric matrix, plasticizer, and temperature have been studied, and the morphology of films determined by scanning electron microscopy (SEM) and confocal fluorescence microscopy. We have used ink jet printing to produce sensor films containing both sensor element and a fluorescence reference. In addition, a high dynamic range, intensity-based fluorometer, using a laser diode and a filtered photodiode was developed for use with this system.
Design of UAV-Embedded Microphone Array System for Sound Source Localization in Outdoor Environments
Authors: Hoshiba Kotaro , Washizaki Kai , Wakabayashi Mizuho , Ishiki Takahiro , Kumon Makoto , Bando Yoshiaki , Gabriel Daniel , Nakadai Kazuhiro , Okuno Hiroshi
Published: November 2017

In search and rescue activities, unmanned aerial vehicles (UAV) should exploit sound information to compensate for poor visual information. This paper describes the design and implementation of a UAV-embedded microphone array system for sound source localization in outdoor environments. Four critical development problems included water-resistance of the microphone array, efficiency in assembling, reliability of wireless communication, and sufficiency of visualization tools for operators. To solve these problems, we developed a spherical microphone array system (SMAS) consisting of a microphone array, a stable wireless network communication system, and intuitive visualization tools. The performance of SMAS was evaluated with simulated data and a demonstration in the field. Results confirmed that the SMAS provides highly accurate localization, water resistance, prompt assembly, stable wireless communication, and intuitive information for observers and operators.
Reducing Impact of Negative Complexity on Sustainability of Mass Customization
Authors: Modrak Vladimir , Soltysova Zuzana , Modrak Jan , Behunova Annamaria
Published: November 2017

In the mass customization environment, product platform development includes several aspects. One relates to the extent to which products are customized. Usually, a high level of product variety brings significant benefits to customers. On the other hand, a high degree of product customization may have a negative environmental impact during production, due to higher material usage. One possible way to reduce the impact is eliminating infeasible configuration options, caused by incompatibilities between optional component types, within a product platform. Such optional components are a source of negative complexity. However, a reduction of optional component types within a product platform can lead to decreasing the extent of the variety of a product to an undesirable level. An effective way of finding this optimal level of reduction is to quantify and analyze the rates between positive and negative complexities, which are related to the numbers of configuration options. The method for this purpose is presented in this paper.