bluuebunny/crossref_metadata_2025 huggingface dataset:
Perioperative fluctuation and overall evaluation of adenohypophyseal hormone secretion in patients with nonfunctioning pituitary adenoma
Authors: Pei Zhijie , Fang Yi , Mu Shuwen , Li Jun , Feng Tianshun , Lin Kunzhe , Wang Shousen
Published: December 2022

OBJECTIVE

Perioperative adenohypophyseal hormone assessment can improve therapeutic strategies and be used to evaluate the prognosis of pituitary adenomas. An individual hormone level does not entirely reflect the pituitary gland. Thus, this study aimed to analyze perioperative hormonal changes and propose a normalized method to facilitate overall assessment of the adenohypophysis.

METHODS

The authors retrospectively analyzed 89 male patients with nonfunctioning pituitary adenoma (NFPA) who underwent transsphenoidal surgery. Preoperative clinical data, imaging data, and perioperative hormone levels of the anterior pituitary gland were evaluated. Hormone values were rescaled using minimum-maximum normalization. The sum of the normalized hormone levels was defined as the total hormonal rate (THR).

RESULTS

Preoperative findings indicated correlations among different adenohypophyseal hormones. Luteinizing hormone (p = 0.62) and adrenocorticotropic hormone (p = 0.89) showed no significant changes after surgery, but growth hormone levels increased (p < 0.001). On the contrary, the levels of thyroid-stimulating hormone (p < 0.001), follicle-stimulating hormone (p = 0.02), and prolactin (p < 0.001) decreased. THR indicated a significant postoperative reduction in adenohypophyseal function (p = 0.04). Patients with postoperative hypopituitarism had significantly lower THR than those without (p = 0.003), with an area under the curve of 0.66. For NFPAs that presented with normal preoperative hormone levels, THR was a good clinical predictor of immediate postoperative hypopituitarism, with an area under the curve of 0.74.

CONCLUSIONS

The normalized synthesis index of hormones is a novel and clinically valuable method used to reflect adenohypophyseal secretion. Compared with individual hormones, these results indicated that THR can facilitate the analysis of general hormone levels despite various fluctuations in adenohypophyseal hormones. THR may also contribute to the effective prediction of short-term surgery-induced hypopituitarism.
Cortical mapping in glioma surgery: correlation of fMRI and direct electrical stimulation with Human Connectome Project parcellations
Authors: Bennett Carlos , González Matías , Tapia Gisella , Riveros Rodrigo , Torres Francisco , Loyola Nicole , Veloz Alejandro , Chabert Stéren
Published: December 2022

OBJECTIVE

Noninvasive brain mapping with functional MRI (fMRI) and mapping with direct electrical stimulation (DES) are important tools in glioma surgery, but the evidence is inconclusive regarding the sensitivity and specificity of fMRI. The Human Connectome Project (HCP) proposed a new cortical parcellation that has not been thoroughly tested in a clinical setting. The main goal of this study was to evaluate the correlation of fMRI and DES mapping with HCP areas in a clinical setting, and to evaluate the performance of fMRI mapping in motor and language tasks in patients with glioma, using DES as the gold standard.

METHODS

Forty patients with supratentorial gliomas were examined using preoperative fMRI and underwent awake craniotomy with DES. Functional activation maps were visualized on a 3D representation of the cortex, classified according to HCP areas, and compared with surgical mapping.

RESULTS

Functional MRI was successful in identifying language and motor HCP areas in most cases, including novel areas such as 55b and the superior longitudinal fasciculus (SLF). Functional MRI had a sensitivity and specificity of 100% and 71%, respectively, for motor function in HCP area 4. Sensitivity and specificity were different according to the area and fMRI protocol; i.e., semantic protocols performed better in Brodmann area (BA) 55b/peri-sylvian language areas with 100% sensitivity and 20% specificity, and word production protocols in BAs 44 and 45 with 70% sensitivity and 80% specificity. Some compensation patterns could be observed, such as motor activation of the postcentral gyrus in precentral gliomas.

CONCLUSIONS

HCP areas can be detected in clinical scenarios of glioma surgery. These areas appear relatively stable across patients, but compensation patterns seem to differ, allowing occasional resection of activating areas. Newly described areas such as 55b and SLF can act as critical areas in language networks. Surgical planning should account for these parcellations.
Takayasu's Arteritis: A Case Report
Authors: Khadka Arzoo , Singh Sumi , Timilsina Sarika
Published: December 2022

Takayasu's arteritis is a chronic vasculitis of medium and large vessels. The most involved vessel is the aorta and its major branches. The disease is primarily seen in young women. The described incidence of the disease ranges from 0.3 to 3.3 million per year. The vessels are characterized by mononuclear infiltration and granulomatous inflammation of vascular media, which leads to arterial wall thickening with stenosis, occlusion, and aneurysmal dilation. Here we present a case of Takayasu's arteritis in a 26-year-old woman who presented with syncope and dizziness with thickened walls of the arch of the aorta and its branches in Magnetic Resonance Imaging angiogram finding. Women of Japanese descent are not the only ones who can develop Takayasu's arteritis; it can affect anyone. Therefore, early diagnosis and treatment are warranted. When the disease is dormant, the outcome seems favourable.
Acute Kidney Injury among Patients Visiting the Nephrology Unit in a Tertiary Care Centre: A Descriptive Cross-sectional Study
Authors: Agrawaal Krishna Kumar , Raghubanshi Prabesh , Bohaju Anjana , Acharya Jiya
Published: December 2022

Introduction: Acute kidney injury is an abrupt decline in renal function often associated with a decrease in urine output. It is the leading cause of in-hospital mortality worldwide with prolonged hospital stays, the requirement of mechanical ventilation and short-term dialysis. The aim of the study was to find out the prevalence of acute kidney injury among patients visiting the Nephrology unit in a tertiary care centre.
Methods: This descriptive cross-sectional study was done among patients presented to the Nephrology Unit of the Department of Internal Medicine in a tertiary centre from 9 February 2022 to 21 October 2022. Ethical approval was taken from Institutional Review Committee (Reference number: UCMS/IRC/047/22). Data was collected from hospital records and the outcome was recorded in terms of in-hospital mortality and the requirement for renal replacement therapy. Convenience sampling was done. Point estimate and 95% Confidence Interval were calculated.
Results: Among 1848 patients, 113 (6.12%) (5.03-7.21, 95% Confidence Interval) had acute kidney injury. About 38 (32.75%) required inotropes whereas 10 (8.85%) required mechanical ventilation. In-hospital all-cause mortality was seen in 14 (12.39%) of the study population and 20 (17.70%) of the study population required renal replacement therapy. The most common cause of acute kidney injury was infection pneumonia followed by acute gastrointestinal infections were the most common infective aetiology.
Conclusions: The prevalence of acute kidney injury was found to be lower than the studies done in similar settings. It is common in patients admitted with infection. It is responsible for in-hospital mortality.
Authentic Leader and Employee’s Silence Behavior: Testing a Happiness at Work Mechanism
Authors: Abdillah Muhammad Rasyid , Anita Rizqa , Agusanto Agusanto , Rahmat Adi
Published: December 2022

A study that tries to explain more deeply the mechanism underlying the relationship between authentic leadership and silence behavior has not been explored. Hence, the study trying to investigate it is still needed. This study endeavor to explain the relationship between authentic leadership and subordinates’ silence behavior. Specifically, this study utilized happiness at work as a psychological mechanism underlying the relationship between the two variables. The current study involved 310 full-time worker who work as government officers in government institutions in a province in Indonesia and used PLS-SEM analysis to test hypotheses. The study finding revealed that authentic leadership has a negative effect on subordinates’ silence behavior. Furthermore, this study also revealed that happiness at work mediates the relationship between authentic leadership and subordinates’ silence behavior. The study finding provides advanced knowledge about the function of authentic leadership in organizations to shapes positive attitudes and prevents negative behaviors, such as silence behavior..
Mengapa Perilaku Burnout dikuatirkan oleh Para Manager di Industri Manufaktur?
Authors: Soelton Mochamad , Nurfakhriansyah Alif Rafi , Apriadi Intan , Arief Harefan , Noermijati Noermijati , Vizano Nico Alexander
Published: December 2022

Karyawan yang memiliki tingkat kejenuhan paling tinggi kemungkinan besar akan mengundurkan diri dari pekerjaannya sehingga pekerjaannya tidak maksimal, seperti persaingan tidak sehat antar sesama karyawan, kurangnya kepuasan dalam bekerja, hal inilah yang menyebabkan gejala burnout pada karyawan. Penelitian ini bertujuan untuk menguji dan menganalisis pengaruh beban kerja dan efikasi diri terhadap burnout yang dimediasi oleh stres kerja. Penelitian ini dilakukan dengan menggunakan metode deskriptif pada PT Intan Metalindo dengan sampel sebanyak 75 responden. Pendekatan yang digunakan dalam penelitian ini adalah Structural Equation Model (SEM) dengan alat analisis Partial Least Square (PLS). Hasil penelitian menunjukkan bahwa beban kerja dan efikasi diri berpengaruh positif dan signifikan terhadap stres kerja. Stres kerja berpengaruh positif dan signifikan terhadap burnout. Beban kerja dan efikasi diri berpengaruh positif dan signifikan terhadap burnout. stres kerja tidak memediasi pengaruh beban kerja terhadap burnout. Stres kerja tidak memediasi efek efikasi diri terhadap burnout.
Strategi Social-Interactive Marketing Dalam Rangka Menciptakan Brand Awareness dan Brand Image Produk Mobil BEV (Battery Vehicle) Indonesia
Authors: Triyono Rudi , Mutia Yustina Andra , Purwansya Yuvicko Gerhaen , Hidayati Nurul
Published: December 2022

Kesepakatan pada konferensi perubahan iklim PBB (Perserikatan Bangsa Bangsa) di Paris pada Desember 2015 mengenai isu lingkungan dan sekuriti energi menjadikan negara-negara, tidak terkecuali Indonesia mendukung perkembangan energi terbarukan dan meminimalkan konsumsi minyak bumi. Salah satu upaya yang dilakukan adalah memproduksi mobil listrik berupa BEV (Battery Vehicle). Namun pada tahun 2020, pemasaran mobil listrik di Indonesia mengalami kegagalan yang diakibatkan oleh adanya pandemi Covid-19. Penelitian ini bertujuan untuk melakukan riset pasar dan konsumen terkait otomotif dan mobil listrik; menganalisis hasil riset untuk menentukan strategi perencanaan pemasaran BEV; dan mengidentifikasi strategi komunikasi pemasaran terintregrasi BEV berdasarkan consumer journey dan target pasar yang sesuai. Penelitian dilakukan melalui kegiatan studi literatur dan wawancara menggunakan kuesioner pada bulan Mei-Juni 2021 dengan melibatkan 50 responden. Analisis yang dilakukan menggunakan analisis deskriptif, analisis STP, analisis bauran pemasaran 4P, Ansoff matrix, analisis SWOT, analisis PESTLE, analisis Porter’s Five Force, dan analisis pemangku kepentingan. Berdasarkan analisis yang dilakukan didapatkan kerangka strategi deployment plan yang terbagi menjadi 3 bagian, yaitu trigger, engage, dan accelerate. Strategi trigger meliputi penggunaan Key Opinion Leaders (KOL) dan influencer,  pameran otomotif,  Search Engine Optimation (SEO), dan Social Media Advertisement.  Strategi  engage  meliputi car green day dan social media interactive content serta strategi accelerate berupa open a virtual factory.
The political summer of 2022 in Japan: A storm before a lull?
Authors: Streltsov Dmitry V.
Published: December 2022

The article addresses the political processes in Japan in the summer of 2022. The central place among them is occupied by the elections to the House of Councilors held in July, which brought victory to the ruling coalition of the Liberal Democratic Party and Komeito. As the main reason for the strong performance of the conservatives in the author views is the fact that Prime Minister Fumio Kishida grasped and duly took into account in his election program a shift to the right in the mainstream sentiment of the Japanese society, under which, against the background of the tightening security environment around Japan, it began to show “understanding” to the growth of military spending, the revision of Article 9 of the Constitution and the abolition of other pacifist restrictions.
Kishida returned to the principles of the inter-factional balance of power in the cabinet reshuffle, introducing a significant number of newcomers in accordance with the wishes of the factional leaders.
Given the current situation in the parliament, as well as the fact that national elections are not expected in Japan until 2025, Kishida received a huge freedom of hands, not being bound by the need to constantly act basing on the considerations of political expediency. So far, he has shown himself to be a loyal disciple of his predecessor Abe, with great reverence for most of his endeavors, but it is still difficult to say whether he will continue Abe’s policy in all areas.
Chinese funding of the Global South: The role of the State Development Bank of China in the African economy
Authors: Matveevsky Sergey S.
Published: December 2022

The article examines China’s financing of the development of the Global South, provides quantitative data, including the implementation of the Chinese initiative “One Belt, One Road”. The author concludes that China, its banks, including the State Development Bank of China (CDB), are actively financing projects and programs in African countries within the framework of “mutual assistance among developing countries”. Projects are being implemented in various sectors of the economy, including infrastructure, agriculture and industry. Project financing is complemented by the development of export-import relations between China and African countries, which involve a large number of Chinese enterprises.
China and African countries use the FOCAC forum for three-year project and program funding planning. In 2021 at FOCAC, the Chinese leadership not only significantly reduced the amount of funding, but also changed its order: now the resources will go to African financial institutions, which will finance the projects.
The CDB, through which China finances projects to a large extent both in Africa and in other countries of the Global South, draws on its many years of experience in the selection, evaluation and implementation of projects in Africa. This makes it possible to ensure the selection of high-quality and relevant for China projects in African countries, to carry out their successful implementation and, as a result, create conditions for economic growth.
PEMANFAATAN TUMBUHAN DAN LIMBAH RUMAH TANGGA SEBAGAI MEDIA PEMBELAJARAN PADA KELOMPOK ANAK
Authors: Menufandu Herlina , Lunga Nelly
Published: December 2022

Media had an important things as an object to got an affective study aims. It is needed by  childrens because they are in concrete think. Conveying infomation through media is help children to accepted and understood what they learn about. So it can be improve knowledge, attitude, and skill ability. Therefore through this community service, children creativity can be improved by utilize plants and house waste as learning media.Teoritical method, field survey, dan practice maked the media were the methods was used in this activity. Some plants such as cucurma, pitaya, red spinach, and pandanus were used as natural colour to added in toy candles, toy sand, and paint. Natural colour from plants is needed for children safety and also founded easly around.Keywords: Plants, house waste, children group
PEMBELAJARAN BAHASA SENTANI UNTUK ANAK MENGGUNAKAN CERITA RAKYAT DI SEKOLAH ADAT SENTANI HOBONG, KABUPATEN JAYAPURA
Authors: Yektiningtyas Wigati , Mantiri Grace J.M.
Published: December 2022

Sentani language used by Sentani people in Jayapura Regency is one of 300 local languages in Papua that is not actively used by most Sentani people, especially children. Preservation of Sentani language by teaching it again is needed especially for children so they will not lose their identity. This Community Service is dissemination of a PDUPT research 2017 entitled “Preservation of Sentani Language for Children using Folktales in Jayapura Regency, Papua” founded by the Ministry of Research, Technology and Higher Education of Republic of Indonesia. One of the research output is a text book of Sentani language teaching for children. This book is used to teach Sentani Language for children in Sentani Customary School in Hobong, Central Sentani, Jayapura Regency. This activity is an initiative of infusing folktales to teach Sentani language for children. Besides involving children, this activity also involved the teachers of the school. Using folktales children learned (1) pronunciation, (2) vocabularies, (3) clause, (4) simple sentences, and (5) counting system. Folktales were also used to introduce them to Sentani’s socio-culture and as media of character building. Keywords: folktales, preservation, Sentani language
NARKOBA, MINUMAN BERALKOHOL DAN PENGARUHNYA BAGI PERKEMBANGAN SISWA DI PERUMAHAN ORGANDA PADANG BULAN
Authors: Sawen Kristina , Ketaren Dahliana
Published: December 2022

Narcotics and alcoholic beverages are a means used to destroy common sense, morals, and morals that have the potential to damage one's personality. Because the working system of this type attacks a person's nerves when consumed. Even so, but the positive benefits for the development of human life in the medical field, so that its existence is permitted but in certain procedures and rules. The result is that it is very detrimental to attack everyone so that uses other than medical interests based on certain permits and procedures are strictly prohibited. Especially when circulating within the children. In fact and fact, still groups of children fall into the life of drugs and alcoholic beverages, so that it will have fatal consequences for the children themselves and for the life of the nation in the future. So it is important to be socialized regularly at every opportunity to help remind children to avoid drugs and alcoholic beverages.Keywords: Narcotics, alcoholic beverages, children
PELATIHAN PEMBUATAN WEBSITE E-COMMERCE PADA MAHASISWA PASCASARJANA MAGISTER MANAJEMEN UNIVERSITAS OTTOW GEISSLER PAPUA
Authors: Bharanti Bonifasia E. , Sampebua Mingsep R.
Published: December 2022

The objective of dedication is to deliver the knowledge and technology throught training in making e-commerce website. The activity can improve the ability and knowledge of graduate students as the partners in the online marketing system and the student can practice to create an e-commerce website by using wordpress.  E-commerce website application is an online business service that is needed to conduct purchases, sales, or exchange of product services and information services throught the internet network. The dedication activities include several stages, namely identification of partner needs, presentation of training materials to partners and practice of making e-commerce website. Keywords: Wordpress, E_commerce, Website training, MM UOG, Dedication
MENINGKATKAN LITERASI ANAK-ANAK MELALUI PENDEKATAN KONTEKSTUAL DI KABUPATEN YALIMO, PAPUA
Authors: Tanjung Rosye H.R. , Yektiningtyas Wigati , Zebua Lisye I.
Published: December 2022

A Slogan says that reading is the world’s window. This expression means that through reading someone is able to see and follow the world’s development, including knowledge. Unfortunately, Indonesian reading habit is still low, especially children’s. This also happens in Yalimo Regency, Papua. As relatively new regency, literacy in the area needs to be improved. This community service initiated various literacy activities to motivate children’s literacy: reading, writing, and numeracy. Contextual approach by adopting environment and socio-cultre is used. This community service was conducted for a month on August 2019 in two districts, namely District Elelim and District Abenaho. The result showed that the contextual approach used in learning process drove the children to be more enthusiastic in learning reading, writing and numeracy. Hopefully, this kind activity will be continued by the stakeholders, literacy tutors, and parents to improve literacy in Yalimo Regency. Keywords: contextual literacy, Elelim, Abenahoi,  Yalimo Regency.
Pengelola Jurnal
Authors: Jurnal Pengelola
Published: December 2022

Pengelola Jurnal
Prototype multi-agent robotic debris removal system: principles of development and experimental studies
Authors: Manko S. V. , Lokhin V. M. , Sekou D.A. K.
Published: December 2022

Objectives. The article substantiates the relevance of the creation and the prospects of application of multi-agent robotic systems for elimination of consequences of emergency situations. The purpose of this work was to test the practical feasibility of algorithms for controlling a group of autonomous robots when performing multi-stage missions.Methods. The theses of the finite automata theory in planning actions of a multi-agent system, methods of automatic control in organizing a goal-directed movement of robots, and methods of computer vision in searching and analyzing debris geometry were used.Results. The principles of development, architecture, and composition are described for the software and algorithms of a prototype of the multi-agent robotic system created at RTU MIREA as part of integrated research for the creation of tools and methods of group control of robots. The multi-stage task of searching and removing debris in the process of eliminating the consequences of emergency situations is analyzed. A proposed algorithm for planning the actions of robotic agents determines the time sequence of the mission stages. Tasks are allocated among the performing robots according to assessments of their suitability. The autonomous functioning of robotic agents is determined by commands coming from the group control level, as well as an a priori embedded knowledge base with scenario models of appropriate actions. Compensation of local environmental uncertainties in the process of robot movement is based on a comprehensive analysis of visual and navigation information. Along with the main elements of the multi-agent system, the developed infrastructure of hardware and software for visual navigation and wireless communication is described.Conclusions. The results of the experimental studies demonstrated the efficiency of the developed approaches to the creation of intelligent technologies for group control of autonomous robots on the example of debris search and removal tasks. The feasibility of the multi-agent robotic system is demonstrated by the development and integration of a number of information management and infrastructure subsystems.
Technology of synthesis and electronic structure of triple barium–strontium–calcium carbonates for cathodes of microwave devices
Authors: Kapustin V. I. , Li I. P. , Kozhevnikova N. E. , Khudaigulova E. F.
Published: December 2022

Objectives. Triple barium–strontium–calcium carbonates of various grades are widely used for depositing oxide coatings on cathodes of electrovacuum devices. Of all types of cathodes used in electrovacuum devices, oxide cathodes are among the most common, due to combining efficiency, durability, operation at relatively low temperatures, and a relatively low cost. The aims of this work were to: create a technology for the synthesis of triple barium–strontium–calcium carbonates with nonequilibrium phase compositions that comprise the triple carbonate proper and a pure barium carbonate phase; develop a quality control procedure for such a carbonate for using it as a component of the cathode material for microwave devices; study how the electronic structure of barium oxide crystallites is affected by doping microimpurities from other phases of the cathode material.Methods. The study used precision X-ray diffraction analysis and electron spectroscopy.Results. A technology was developed for the co-precipitation of triple barium–strontium–calcium carbonates from their nitrate salts. Under optimal precipitation conditions, this produces triple carbonate powders with nonequilibrium phase compositions. Electron spectroscopy showed that the parameters of the electronic structure of the crystallites are significantly affected by doping impurities of calcium, strontium, and nickel in barium oxide crystallites formed by heat treatment of triple carbonates.Conclusions. Calcium and strontium have a synergistic effect on the doping of barium oxide with the two other chemical elements. As well as efficiently controlling the quality of the nonequilibrium phase composition of triple carbonates, which is formed during the synthesis of triple carbonates by the titration method, precision X-ray diffraction analysis can be used to efficiently control the processes of agglomeration of nanoparticles or recrystallization of nanostructured phases formed during the synthesis of triple carbonates.
Prospects of two-port vitrectomy in the treatment of patients with epiretinal fibrosis
Authors:   Cheboksary Branch of the S. Fyodorov Eye Microsurgery Federal State Institution, Cheboksary, Russian Federation, Borisova D.V. , Frolychev I.A. ,   Cheboksary Branch of the S. Fyodorov Eye Microsurgery Federal State Institution, Cheboksary, Russian Federation,   Postgraduate Doctors Training Institute, Cheboksary, Russian Federation, Pozdeeva N.A. ,   Cheboksary Branch of the S. Fyodorov Eye Microsurgery Federal State Institution, Cheboksary, Russian Federation,   Postgraduate Doctors Training Institute, Cheboksary, Russian Federation
Published: December 2022

Aim: to evaluate the efficacy and safety of two-port vitrectomy in the treatment of patients with epiretinal fibrosis. Patients and Methods: surgical treatment using a two-port vitrectomy technique was performed in 25 patients (25 eyes) with epiretinal fibrosis. Patients with concomitant retinal pathology (e.g. diabetic or post-thrombotic retinopathy) and glaucoma were not included in the study. Of the total number of patients, 64% (n=16) were women and 36% (n=9) were men. The mean age of the patients was 61±6,4 years. The surgical procedure was based on the developed technology and conducted by the same surgeon in the same clinical setting. The surgical technique included the installation of two ports in the opposite quadrants: in the upper hemisphere for the vitreotome and instruments, and in the lower hemisphere — for the infusion cannula with a built-in endo-illuminator-chandelier as a single light source. Then, vitrectomy was performed according to the classical technique — the vitreous body was removed centrally, followed by membrane staining and membrane peeling, and partial tamponade with an air mixture. Patients were examined on day 1, one and three months after the surgical procedure. They underwent the basic ophthalmic examination, including visometry and tonometry. Optical coherence tomography with retinal image analysis was used to assess the recovery of anatomical parameters. Results: intra- or postoperative adverse events were not reported. All patients had stable anatomical results: the absence of horizontal tractions in the foveal zone and a retinal height reduction to 297±32 μm. The maximum functional effect — a decrease in metamorphopsia expression and an increase in best-corrected visual acuity by 0.48±0.1 vs. that at the baseline was observed 3 months after the surgery. Conclusion: in addition to the classical three-port vitrectomy with xenon focal illuminator, it is possible to use the two-port vitrectomy with a mercury vapor chandelier illuminator. The advantage of this method is the reduction of surgical trauma. Keywords: epiretinal fibrosis, two-port vitrectomy, phototoxicity, tyndallometry. For citation: Borisova D.V., Frolychev I.A., Pozdeeva N.A. Prospects of two-port vitrectomy in the treatment of patients with epiretinal fibrosis. Russian Journal of Clinical Ophthalmology. 2022;22(4):224–227 (in Russ.). DOI: 10.32364/2311-7729-2022-22-4-224-227.
In Search of International Order: The English School Approach to the Analysis of International Politics
Authors: Karmazin Aleš
Published: December 2022

The English School of International Relations is one of the long-established theoretical approaches in IR that systematically explores the purpose and the character of international order at the macro-level of international politics. It does so by analysing deeply embedded (the so-called primary) institutions and other related institutional elements, norms and practices. This paper aims to introduce how the English School theoretically conceptualise and analyse international order. The paper synthetises the core argument of the English School, discusses how recent debates develop it and which key cleavages are present in the English School. I argue and demonstrate that the English School has been dynamically evolving in the last two decades and that it can contribute to our understanding of the changing world. The paper also encourages developments of the English School research in the Czech academic context.
Novel Small Molecule Inhibitor of Osteoclast Differentiation
Authors: Martin Macey , Holliday Lexie , Ostrov David
Published: December 2022

Osteoporosis results in over a million bone fractures each year despite current therapeutics that inhibit bone resorption. The need for better anti-osteoporotic therapeutics is clear. Recently, extracellular vesicles (EVs) containing RANK that are released by osteoclasts and serve as novel regulators of bone remodeling were identified. These RANK-containing EVs both block bone resorption by osteoclasts and stimulate a RANKL reverse signaling pathway in osteoblasts that promotes bone formation. Small molecules with the same activity could prove to be a new class of therapeutic for treatment of bone disease. To seek such small molecules, a virtual screen identified small molecules that were predicted to bind RANKL in the same location as RANK, and an initial cell culture screen showed eighteen of the candidates reduced osteoclast formation in vitro at a concentration of 100 μM. In this project, one candidate, 3-Nitro-4-phosphobenzoic acid (NPA), was examined in greater detail. NPA does-dependently reduced recombinant RANKL-stimulated differentiation of RAW 264.7 cells into osteoclast-like cells with an IC50 of 38 μM. In calcitriol-stimulated mouse marrow, primary cultures that produce both osteoblasts and osteoclasts, NPA (50 μM) reduced osteoclast formation by 88%, while alkaline phosphatase positive osteoblast numbers were higher. These data show that NPA, in cell culture, is able to simultaneously inhibit osteoclast differentiation and promote osteoblast formation. Thus, NPA is a candidate to be a lead molecule for novel dual-function, small molecule, therapeutic agents to treat osteoporosis.
Assessing the Impacts of COVID-19 on K-12 Public School Educators and Administrators on their Practices and Autonomy in East Gainesville
Authors: Kolli Shruti , Morton Eliza , Afridi Abdullah , Zhang Keer , Kim Erin
Published: December 2022

The impacts of the pandemic have rippled through every aspect of daily life; for students and teachers, this manifests predominantly in education. This qualitative case study aimed to evaluate educator opinions on the current state of public education. Data collection consisted of interviewing seven K-12 educators from East Gainesville, a low-income and historically segregated region in Florida, about their experiences teaching during the pandemic. Seven questions captured the largest challenges for educators and students amidst the pandemic. 13 common major themes (nodes) and minor themes (nodes) were identified from these responses. It was found that COVID-19 has had generally negative impacts on the quality of student education and educator morale. Both are partially rooted in the switch from traditional to virtual/HyFlex classrooms, in which educators need to expend much more effort to achieve the same or sometimes worse results. Conversely, there were some benefits of this new education format, including increased versatility, collaboration, and accessibility. Other drawbacks include feelings of isolation for students and inequity for students with less access to technology. Still, educators reported feelings of support from administration and the community and expectations that addressing these challenges would lead to positive changes for education in the future. Ultimately, this study will elucidate the challenges educators face when integrating curricula into virtual platforms, an increasingly popular phenomenon. These findings may serve as guidance for future implementations to promote higher quality, more versatile, and virtual-friendly learning environments.
PENGARUH PREMI PANEN DAN KEPUASAN KERJA TERHADAP KINERJA KARYAWAN PANEN DI PTPN V KEBUN TANDUN KABUPATEN KAMPAR
Authors: Ginting Citra Sania , Hutabarat Sakti , Yusri Jum’atri
Published: December 2022

Karyawan panen merupakan salah satu faktor produksi yang dibutuhkan di dalam perusahaan perkebunan. Karyawan panen harus memberikan prestasi kerja yang baik dengan cara meningkatkan kinerjanya yang dilihat dari kualitas dan kuantitas hasil panen. Salah satu faktor yang dapat meningkatkan kinerja karyawan panen yaitu dengan adanya sistem premi panen dan kepuasan kerja di dalam perusahaan. Penelitian ini bertujuan untuk mengetahui tingkat kepuasan kerja karyawan panen, menganalisis pengaruh premi panen dan kepuasan kerja terhadap kinerja karyawan panen. Penelitian ini dilakukan di PTPN V Kebun Tandun, Kecamatan Tapung Hulu, Kabupaten Kampar dengan menggunakan metode purposive sampling dengan kriteria karyawan panen yang bekerja di kelompok tanaman kelapa sawit yang memiliki umur tanaman, topografi, dan teknik pemanen yang sama. Sampel dalam penelitian ini sebanyak 30 karyawan panen harian tetap. Data yang terkumpul dianalisis menggunakan metode analisis skala likert dan analisis regresi linier berganda. Hasil penelitian menunjukkan bahwa persepsi kepuasan kerja karyawan panen sangat puas. Secara simultan premi panen dan kepuasan kerja berpengaruh signifikan terhadap kinerja karyawan panen. Secara parsial hanya premi panen yang berpengaruh signifikan terhadap kinerja karyawan panen.

Harvest employees are one of the factors of production needed in plantation companies. Harvest employees must provide good work performance by improving their performance as seen from the quality and quantity of the harvest. One of the factors that can improve the performance of harvest employees is the existence of a harvest premium system and job satisfaction within the company. This study aims to determine the level of job satisfaction of harvest employees, analyze the effect of harvest premiums and job satisfaction on the performance of harvest employees. This research was conducted at PTPN V Kebun Tandun, Tapung Hulu District, Kampar Regency using a purposive sampling method with the criteria of harvesting employees working in groups of oil palm plantations that have the same plant age, topography, and harvesting techniques. The sample in this study were 30 permanent daily harvest employees. The collected data were analyzed using the Likert scale analysis method and multiple linear regression analysis. The results showed that the perceptions of job satisfaction of harvest employees were very satisfied. Simultaneously harvest premium and job satisfaction have a significant effect on harvest employee performance. Partially, only the harvest premium has a significant effect on harvest employee performance.
The Connotation and Realization of Student-centeredness at Cardiff University, UK
Authors: Zheng Hong
Published: December 2022

Through field research at Cardiff University in the UK, this paper points out that the connotation of Student-centeredness (SC) can be summarized into four aspects: centering on students' physical and mental health and quality of life, students' participation, students' learning outcomes and students' learning experiences. The core of these four points is centering on students' learning. centered. Cardiff University guarantees the realization of student learning-centered through the establishment of an academic support system, the provision of year-round on/offline training, the development of students' learning skills, and a comprehensive organization and policy, forming the SC university culture that combines ideas and actions. The university culture is a combination of SC philosophy and action, which reveals that Chinese universities in the post-epidemic era need to realize a cultural transformation based on SC, and the concept of SC ultimately needs to be implemented into undergraduate learning-centeredness. Technology, teaching, management need to shift to supporting, guiding and serving all students.
Analysis on Advantages and Disadvantages of Playing Mobile Games among Colleges Students
Authors: Wang Penghui
Published: December 2022

In recent years, smartphone games have developed rapidly thanks to smart media and mobile media. It is popular among college students by virtue of its obvious characteristics, such as the integration of authenticity and virtuality, the intersection of infinity and disorder, and the unity of mobility and sociability. For college students, appropriate time consumed in playing games is beneficial to the development of psychological health, the improvement of intelligence level, which can overcome the sense of alienation caused by social role division. Excessive indulgence will aggravate the psychological cognitive contradictions of college students, hindering the cultivation of good moral behavior, and even going against the steady progress of the society as a whole.
The Role of Cross-linguistic Influence in Second Language Acquisition
Authors: Chen Yudi
Published: December 2022

Cross-Linguistic Influence (CLI) occupies an important but rather complex position in Second Language Acquisition (SLA). It is difficult to determine its specific role, but by observing research and theories, its impact on SLA can be divided into two types, positive and negative. The role of CLI in SLA largely depends on the similarities and differences between L1 and L2, and the contact of these two languages. In addition, cross-cultural influence must also be considered, its relationship with CLI, and its role in SLA. This paper will also briefly discuss some factors that affect CLI because CLI does not exist in isolation, nor is it immutable.
Dampak Gangguan Tidur terhadap Status Gizi pada Remaja
Authors: Annisa Fitri , Setiarini Tatik
Published: December 2022

Masalah kelebihan berat badan pada remaja semakin meningkat dari tahun ke tahun. Menurut Riskesdas tahun 2018, berat badan lebih dan obesitas pada remaja usia 13-15 tahun sebesar 16,0% dan pada remaja usia 16-18 tahun sebesar 13,5%. Kelebihan berat badan disebabkan oleh berbagai macam kondisi yang mempengaruhi, salah satunya adalah kualitas tidur pada remaja. Tujuan dari penelitian ini adalah untuk mengetahui hubungan antara gangguan tidur dengan status gizi pada remaja usia 12-15 tahun. Metode penelitian bersifat kuantitatif dengan desain potong lintang pada 100 remaja berusia 12-15 tahun yang berada di Jakarta Selatan. Analisis korelasi gangguan tidur dan status gizi menggunakan uji Spearman sommers’d gamma.  Berdasarkan hasil penelitian terdapat 24 remaja (88,8%) dengan gangguan tidur yang mengalami gizi lebih, kemudian terdapat 9 remaja (90%) dengan gangguan tidur yang mengalami obesitas, dan terdapat 50 remaja (81,9%) dengan ganguan tidur dengan gizi baik. Tidak ada korelasi yang signifikan antara gangguan tidur dengan status gizi pada remaja (p=0,404). Pada penelitian ini gangguan tidur dapat terjadi pada remaja dengan status gizi apapun. Tingginya angka gizi lebih dan obesitas pada remaja menandakan bahwa diperlukan perhatian dan penelitian lebih lanjut terkait faktor lain yang mempengaruhinya.
Terapi “Sehat Jasmani dan Rohani” Menurunkan Tingkat Kecemasan Lansia
Authors: Riyanti Eska , Pudjiati Pudjiati , Yardes Nelly
Published: December 2022

Masalah psikologis yang paling banyak diderita oleh para lanjut usia adalah kecemasan. Adapun penyebab yang umumnya ditemui diantaranya:  (1) Kurangnya aktifitas sosial dengan teman atau relasi  (2) Kehilangan pasangan  (3) Kehilangan hubungan dengan anak-anak yang menikah (4) Menghadapi kematian. Paket “SAHAJA” atau “Sehat Hati dan Jiwa“ merupakan bentuk psikoterapi yang dikembangkan peneliti untuk menurunkan tingkat kecemasan pada lansia dengan menggabungkan beberapa bentuk psikoterapi yaitu relaksasi dan berdzikir. Penelitian ini bertujuan mengetahui pengaruh paket “SAHAJA” terhadap tingkat kecemasan lansia. Populasi dari penelitian adalah seluruh lansia dengan teknik sampling menggunakan simple random sampling, besar sampel 30 orang. Desain penelitian yang digunakan dekriptif analitik dengan pendekatan kuasi ekperimen. Uji analisis data yang digunakan adalah univariat, bivariat dengan paired t-test untuk pengaruh intervensi paket “SAHAJA” terhadap tingkat kecemasan lansia. Hasil penelitian diketahui adanya pengaruh pemberian terapi “SAHAJA” terhadap tingkat kecemasan lansia. Dengan melakukan terapi “SAHAJA” secara teratur dalam waktu dan jangka waktu yang lebih lama dapat memberikan pengaruh yang lebih efektif lagi dalam menurunkan tingkat kecemasan lansia.
New Day, New Game: Examining Consumer Needs in Daily Fantasy Sports
Authors: Sears Jackson , Kang Philip , Ko Yong Jae , Lee Joon Sung
Published: December 2022

Abstract: The aim of the current research was to identify consumer needs that significantly influenced daily fantasy sports (DFS) consumption. Specifically, we sought to predict DFS participation intention and information search. Existence, relatedness, and growth (ERG) theory and self-determination theory (SDT) served as theoretical inspirations for need selection. The needs included were needs for autonomy, arousal, uniqueness, status, achievement, competence, and relatedness. The results of the current study indicate that autonomy and achievement needs are important for DFS consumers. Additionally, highly involved DFS participants are more likely to be driven by needs competence, while low involvement players showed relatively higher level of needs for arousal and uniqueness drove their DFS participation intention. These results from our model can be used by industry professionals in the DFS space to better understand the consumer needs and develop effective market strategies within daily fantasy sports.
Effect of Consumer Experience Quality on Participant Engagement in Japanese Running Events
Authors: Yamaguchi Shiro , Yoshida Masayuki
Published: December 2022

Abstract: This study examines the influences of core product quality, service quality, social network quality, and event satisfaction on participant engagement using the conceptual framework of consumer experience quality and customer engagement theory in sport. The study surveyed 452 runners after they finished the Ako City Marathon. We divided the core product quality into event characteristics and physical changes and service quality into event staff and service environments. Participant engagement included prosocial behavior, management cooperation, and behavioral loyalty. The results revealed that event characteristics in core product quality and service environment in service quality positively influenced event satisfaction. Additionally, social network quality positively influenced prosocial behavior, management cooperation, and behavioral loyalty. Finally, event characteristics and service environments had a significant indirect effect on behavioral loyalty through event satisfaction.
Exploring health care for transgender people in the Brazilian health system: Qualitative descriptive-interpretative study
Authors: De Faria Mateus , Paiva Tiago Sousa , Cornelli Andressa Marques , Voigt Carolina Feijó Bitencourt , Rocha Cristianne Maria Famer , Modena Celina Maria
Published: December 2022

The guarantee of rights in Brazil is legitimized through its Constitution of the Republic and its national health system needs to follow a list of prerogatives that include, also, transgender people. Currently there are situations in which the expectation of rights is broken and the free exercise of life of this population is prevented. This article analyzes access to health services by trans people in the health system in Brazil. The investigation was carried out in cities in the metropolitan region of a municipality in southeastern Brazil, through qualitative, exploratory and descriptive-interpretive research. The trans population faces many difficulties in accessing the services that make up the Brazilian Health System, such as the lack of qualification of health professionals, barriers to the use of the social name and structural prejudices in society.
The mental well-being of children and adolescents during the COVID-19 pandemic: A systematic review of qualitative literature
Authors: Subasinghe Kalpana , Pathiranage A.M.Shyama Deepanie
Published: December 2022

COVID-19 has led to significant isolation resulting in a rise in educational inequity and mental illness among youth. A systematic literature review of qualitative studies was conducted adhering to PRISMA 2020 guidelines, to describe the mental wellbeing of children and adolescents during the COVID-19 pandemic. The protocol has been registered in the PROSPERO International Prospective Register of Systematic Reviews. Three Electronic databases were searched for original, qualitative, peer-reviewed, full text, English journal articles published from December 2019- to May 2020, conducted among children and their parents. We extracted the results that describe the psychological impact on children and their parents amidst COVID-19. Thirteen studies were included in the final review. Four major themes (1. Negative and maladaptive behavior 2. Social and psychological disruption 3. Emotion regulation 4. Value of family time) were identified through Inductive Thematic Synthesis. Although children regulate their emotions effectively, most of the children seem to experience maladaptive behaviors which may have a devastating effect on their development. Health care professionals, caregivers, school officials, and social workers should address these aspects of childcare during a pandemic and in the post-pandemic period.