bluuebunny/crossref_metadata_2025 huggingface dataset:
Intervenciones asistidas por animales y calidad de vida: expectativas en estudiantes universitarios españoles
Authors: Perea-Mediavilla María A. , López-Cepero Javier , Tejada-Roldán Arcadio , Sarasola José Luis
Published: September 2021

El presente estudio evalúa las expectativas mantenidas por estudiantes universitarios (N= 474; X= 22,7 años; DT= 5,6 años) hacia las ventajas que las intervenciones asistidas por animales proporcionan para mejorar la calidad de vida en distintos colectivos. Los resultados fueron extraídos del Mejora de Calidad de Vida, un instrumento de elaboración propia que mostró adecuadas cualidades psicométricas (cuatro factores de fácil interpretación, con un 49% de varianza explicada y alfas comprendidas entre ,76 y ,89), y mostraron actitudes muy positivas (tamaño de efecto grande; TE>,80) con independencia de la rama de conocimiento de los participantes (Ciencias Sociales, Sanitarias o de la Educación). Haber convivido con mascotas se asoció con mejores expectativas. El presente estudio puso de relieve las buenas expectativas mantenidas por los futuros profesionales de distintos ámbitos de intervención sobre las intervenciones asistidas por animales, a la vez que subrayó las carencias formativas existentes en los actuales planes de estudio. Por último, se discuten las implicaciones de estos hallazgos para el desarrollo de intervenciones asistidas por animales.
Más allá de la obediencia: reanálisis de la investigación de Milgram
Authors: Canto Ortiz Jesús M. , Álvaro José L.
Published: September 2021

Los experimentos de Milgram sobre la obediencia a la autoridad son considerados una de las investigaciones más importantes de la psicología social. Su impacto ha abarcado tanto a la psicología social como a otras ramas de la psicología, incluidas otras ciencias sociales. En este trabajo se analiza la influencia recíproca de la investigación de Milgram y el concepto de la banalidad del mal de Arendt. Se critica el modelo teórico propuesto por Milgram y el concepto de la banalidad del mal de Arendt. No hay ninguna demostración empírica de la existencia del estado agén-tico y de la relación entre éste y los niveles de obediencia obtenidos en los experimentos de Milgram. Además, obras recientes sobre el Holocausto no confirman que las acciones criminales de los líderes nazis se debieran a actos de obediencia debida. Son necesarios modelos teóricos como el que se basa en la perspectiva de la identidad social para explicar los datos obtenidos en el experimento de Milgram.
Merging Policy Initiatives and Developmental Perspectives in Early Intervention
Authors: Guralnick Michael J.
Published: September 2021

The provision of early intervention services for vulnerable children and their families is now both accepted and expected by the international community. This article considers the importance of a developmental perspective as an essential guide to early intervention service systems. Emphasized in this framework are three critical features: relationship formation, the continuity of interventions, and the comprehensiveness of interventions. Guidance to early intervention systems design with respect to structural and values principles is also discussed. Future advances in early intervention may well depend upon the merging of these perspectives to create policy initiatives to enhance early intervention systems.
Vínculo materno-fetal: implicaciones en el desarrollo psicológico y propuesta de intervención en atención temprana
Authors: Roncallo Claudia Patricia , Sánchez de Miguel Manuel , Arranz Freijo Enrique
Published: September 2021

Diversas investigaciones en el campo de la salud identifican el vínculo materno-fetal como un precedente significativo de la vinculación post-natal entre la madre y su bebé. El vínculo materno-fetal se asocia con aspectos emocionales y cognitivos que permiten recrear al feto como otro ser humano. Este vínculo se expresa, a través de prácticas de salud dirigidas a buscar la protección y el bienestar del feto. Por otra parte se constata que el estado psicológico de la madre influye en el feto, tanto a nivel neurocomportamental y en las alteraciones en el desarrollo que se manifiestan así mismo en el periodo post-natal, afectando significativamente la relación madre-bebé. Por tanto cabe proponer que las prácticas de atención temprana se extiendan al periodo prenatal como estrategia de prevención, repercutiendo favorablemente en la salud materno-infantil. Para ello se plantea un modelo de intervención interdisciplinar, centrado en el vínculo materno-fetal como factor protector del vínculo en el período post-parto y como potenciador de prácticas de parentalidad positiva que fomente un desarrollo psicológico saludable.
Intervención asistida con animales (IAA): Análisis de la situación en España
Authors: Martos-Montes Rafael , Ordóñez-Pérez David , De la Fuente-Hidalgo Inmaculada , Martos-Luque Rafael , García-Viedma Mª Rosario
Published: September 2021

En este estudio se describe la actividad profesional de las principales entidades (instituciones, empresas, fundaciones, asociaciones, etc.) que en España se dedican de manera sistemática y continuada a la Intervención asistida con animales (IAA), incluidas la Terapia (TAA), las Actividades (AAA) y la Educación asistidas con animales (EAA). La Intervención asistida con animales en España está experimentando en la actualidad un gran auge y expansión. El estudio recoge la actividad de 275 profesionales que, junto a 213 animales, pertenecen a 55 entidades distribuidas por toda España. Todas ellas se dedican a desarrollar programas de Intervención asistida con animales de manera sistemática y continuada. Estas entidades se definen por su carácter multiprofesional aglutinando trabajadores de disciplinas diversas, tales como el adiestramiento animal, la psicología y la educación, fundamentalmente. Su actividad principal es la terapia asistida con animales, siendo sus ámbitos de actuación prioritarios la neurorehabilitación, la educación, la psicología/psiquiatría, la integración social y la gerontología. En el futuro, estudios similares comprobarán si esta tendencia expansiva sigue creciendo o se estabiliza.
Tratamiento de un caso de disfunción eréctil mediante terapia de pareja y terapia sexual
Authors: Valero Aguayo Luis , Bernet Carrero Jonatán
Published: September 2021

En este estudio de caso único se presenta el tratamiento de un varón de 22 años afectado por un trastorno de disfunción eréctil. La evaluación inicial evidenció problemas en la relación de pareja como base de los problemas de erección del hombre, por lo que se decidió combinar un trabajo en sesión mediante terapia sistémica de pareja con ambos miembros, y al mismo tiempo diversas técnicas conductuales de terapia sexual (egoísmo sexual, focalización sensorial), y también instrucciones y ejercicios para realizar en casa. Esta combinación de terapias tenía por objetivos tratar el problema de disfunción eréctil del hombre, y al mismo tiempo mejorar la relación de pareja para que ello repercutiese en ese problema sexual. Se realizó un diseño de caso único mediante la evaluación continua de línea-base del funcionamiento sexual a través de autorregistros diarios sobre su desempeño y satisfacción con la relación sexual. Además se realizó una evaluación pre, post y seguimiento con diversos cuestionarios específicos. El proceso terapéutico se completó en siete sesiones a lo largo de tres meses, y una de seguimiento un año después. Los resultados de los cuestionarios muestran el éxito del tratamiento y su mantenimiento posterior, además los datos de evaluación continua demuestran también ese efecto progresivo del tratamiento. Al finalizar el caso ya no había disfunción eréctil y sí una satisfacción total de la pareja con sus relaciones personales y sexuales.
Prevalence of dental caries in the Late Neolithic and Early Bronze Age populations from Żerniki Górne (Poland)
Authors: Tomczyk Jacek , Rusin Paweł , Zalewska Marta
Published: September 2021

The aim of the studies is to describe the prevalence and distribution of dental caries in two pop­ulations from Żerniki Górne (Poland). The first population represented the Corded Ware Culture (CWC) (2550–2350 BC), and the second population belonged to the Trzciniec Culture (TC) (1300–1000 BC). While the TC is identified with a typically agricultural strategy, the CWC culture strategy is still debatable. Two types of strategies are indicated in the CWC, either a mixed or typical agricultural economy.  
A total of 110 adults were examined, of which 29 represented the CWC and 81 belonged to the TC. A total of 1132 permanent teeth were examined (CWC 379, TC 753).  
Of the 110 individuals, 54 individuals had dental caries (CWC 19/29, 66%; TC 35/81, 43%). In the CWC, 68% (13/19) of males and 60% (6/10) of females had dental caries. In the younger period (TC), the per­centage of dental caries among males was little higher (45%) than among females (41%). Dental caries was identified in 13% (50/379) of the teeth from the CWC. In the TC, the percentage of affected teeth were similar (11%, 82/753). The most common location of caries in all the chronological periods were the approximal and cemento-enamel junction [CEJ] surfaces. Caries on the occlusal surface was much less frequent. If we assume that an important cause of the development of dental caries is a high-carbohydrate diet, we can conclude that a similar prevalence of teeth affected by caries and it locations indicate a similar management strategy in both populations.
Performance and Consequences for Fecal Transplant in the Treatment of Pseudomembranous Colitis
Authors: Aurelia Hangan , Sorin Rugina , Elena Mocanu , Eugen Dumitru , Magdalena Dumitru Irina
Published: September 2021

Under conditions of increased consumption of antibiotics, pseudomembranous colitis has become a common condition in Romanian hospitals. Severe forms of the disease are becoming more common, recurrences are numerous, and metronidazole and vancomycin therapy has failed to prevent these recurrences. The study aims to identify the characteristics of patients who require a fecal transplant, the time for its performance and what are the short-term and possibly long-term consequences of this method.

We analyzed 26 patients who had a fecal transplant with a favorable evolution in 96%. We consider that FMT is an effective method for preventing recurrent CDI but also for those with resistance to the usual antibiotics.
Proteomic Implications of Tumoral Infiltrating Lymphocytes in Melanoma: PD-L1, CD4 and CD8 - Short Review
Authors: Antonela Nicolau Anca , Marian Caraban Bogdan , Emma Gheorghe , Laurentiu Hangan Tony , Oana Cojocaru , Ionut Orasanu Cristian , Ioana Voda Raluca
Published: September 2021

Melanoma is a tumor developed by malignancy of melanocytes, being one of the most lethal cancers. Usually, it is associated with exposure to ultraviolet radiations, being most common in the skin, but can also be located extracutaneously as in the digestive tract, leptomeninges or uvea. Histopathologically it presents a phase of radial growth and a vertical one, often accompanied by an intra and peritumoral inflammatory infiltrate. Immunohistochemically, the confirmation of the diagnosis of melanoma should be accompanied by the assessment of proteomic markers of lymphocytic infiltrate such as PD-L1, CD4 and CD8. Those have a role in evaluating the prognosis and a possible prediction of the immunotherapeutic response.
The Efficiency of the Fight Against HIV, in Constanta, from the Perspective of Neurological Complications
Authors: Corina Pascu , Magdalena Dumitru Irina , Carmen Cernat Roxana , Cristian Petcu Lucian , Sorin Rugina
Published: September 2021

In order to control and end the AIDS epidemic, we all need to hit the 0-0-0 target. That means 0 HIV infections, 0 mortality caused by AIDS and 0 discrimination. We performed a retrospective observational analytical study on 166 HIV positive patients with a neurological complication, diagnosed between June 2012 and June 2020, in Clinical Infectious Diseases Hospital of Constanta. We collected data from the observational charts that revealed if the patient was known with HIV infection at the time of the neurological complication diagnosis, information about the treatment (how many treatment regimens, classes of antiretroviral drugs, CNS Penetration-Effectiveness Rank), treatment compliance. The patients were divided into two groups: first group “opportunistic infections (OI)” and second group “other neurological conditions (ONC)”. 16 patients (9,6%) have the neurological condition as first manifestation of HIV infection. Opportunistic infections, correlated with a poor immunological status continue to have a high percentage (46,98%) of neurological complications, being associated with a poor treatment compliance (p<0,001). Integrase inhibitors were associated, in this study, more with opportunistic infections and less with other neurological conditions (OR=2,885; 95% IC), this finding needs further research. Long term survivors have problems with treatment compliance manifesting treatment fatigue, even if they have treatment regimens with good CNS penetrability. Poor compliance is associated with high risk of opportunistic infections and opportunistic infections have a higher mortality than other neurological complications. Our task for the future is to find ways to improve treatment adherence in order for HIV patients to have a better and longer life.
Square Slot Antenna for Wide Circularly Polarized Bandwidth and Axial Ratio Beamwidth
Authors: Sharma Vijay , Jhajharia Tejpal
Published: September 2021

The article proposes design investigation and experimental results of a coplanar waveguide (CPW) fed square slot antenna that gives wideband circular polarization. This circular polarization characteristic is achieved by embedding a square shape stub to left bottom corner and an L-shaped strip to the right upper corner of the slot. A high impedance bandwidth of 87.8 % (3.6–9.0 GHz), a wide axial ratio bandwidth of 73.05 % (4.2–9.0 GHz) and wide 3-dB axial ratio beamwidth of 90° in the entire frequency range of interest are achieved with this antenna structure. To improve the 3-dB axial ratio bandwidth, three slots (two horizontal and one vertical) are scratched at the exterior periphery of the ground plane. These perturbation assemblies are accountable to excite orthogonal modes and help increase an axial ratio bandwidth. The designed antenna displays the constant and steady radiation patterns in the complete frequency range of concern. The overall dimension of the presented compact antenna is 0.24λ × 0.24λ × 0.01λ.
Does dehydroepiandrosterone sulfate have a role in COVID-19 prognosis and treatment?
Authors: Tomo Sojit , Banerjee Mithu , Sharma Praveen , Garg Mahendra
Published: September 2021

The pathophysiology of COVID comprises an exaggerated pro-inflammatory response. Hypothalamic-pituitary-adrenal (HPA) axis has a crucial role in various inflammatory conditions and modulated immunological response. Limited evidence is available regarding the incidence and the effect of HPA dysfunction in COVID-19. Although the cortisol levels have only been estimated in a few studies, the dehydroepiandrosterone sulfate (DHEAS) release from the adrenal gland has not been explored yet. In this mini review, the authors discuss the role of dehydroepiandrosterone (DHEA) and DHEAS in the acute stress response and immunological modulation. Various effects of DHEAS have been demonstrated in different diseases. The specific inhibitory effect of DHEA on interleukin 6 (IL-6) could be of paramount importance in COVID-19. Further, DHEA supplementation has already been proposed in inflammatory conditions, like rheumatoid arthritis. DHEAS levels in COVID-19 may help to understand the HPA axis dysfunction as well as the possibility of repurposing DHEA as a drug for mitigating the pro-inflammatory COVID-19.
Selected 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase inhibitors. A look into their use and potential in pre-diabetes and type 2 diabetes
Authors: Barre Douglas Edward , Mizier-Barre Kazimiera Amelia
Published: September 2021

Objectives. This review assesses the comparative safety and efficacy of selected 3-hydroxy-3-methylglutaric acid coenzyme A inhibitors (statins, cinnamic acids. 3-hydroxy-3-methyl glutaric acid) on the pre-onset type 2 diabetes (PT2D) and post-onset type 2 diabetes (T2D)-related cluster of seven features (central obesity, hyperglycemia, hypertension, dyslipidemia, pro-thrombosis, oxidation and inflammation).

Methods. Google scholar and PubMed were searched for statin*, flaxseed lignan complex (FLC), cinnamic acid (CA)*, and 3-hydroxy-3-methylglutaric acid (HMGA) in conjunction with each of PT2D, T2D and the cluster of seven. An introduction was followed by findings or absence thereof on the impacts of each of statins, FLC, CAs and HMGA on each member of the cluster of seven.

Results. Pravastatin manages three features in PT2D, while a number of the statins improve five in T2D. FLC is negative in PT2D but controls four in T2D; it is not clear if the CAs and HMGA in FLC play a role in this success. CAs have potential in six and HMGA has potential in three of the cluster of seven though yet CAs and HMGA are untested in PT2D and T2D in humans. There are safety concerns with some statins and HMGA but FLC and CAs appear safe in the doses and durations tested.

Conclusions. Selected statins, FLC, CAs and HMGA can manage or have a potential to manage at least three features of the cluster of seven. Most of the literature-stated concerns are with select statins but there are concerns (one actual and two potential) with HMGA.
In Search of Outcomes of a Psychological Contract in Public Organisation
Authors: Bera Agata
Published: September 2021

Background

Sustainable development of employees is based primarily on practices oriented towards caring for the relationship between the employer and employee. In this approach, the employee's and the employer's perception of mutual obligations, the employee's belief in the conditions for the exchange of mutual experiences with the employer, and mutual obligations resulting from establishing an employer-employee relationship become important factors and elements of the sustainable development strategy of employees. A growing number of soundscape studies involve a psychological contract literature. However, outcomes have not yet been thoroughly reviewed. The need for a study with this purpose is proven by the fact that academic literature lacks a systematic review of this topic, despite the ascending trend in the number of published articles in the field. Therefore, this study aims at identifying the main outcomes of a psychological contract in public organisations.

Research aims

The purpose of this literature review was to identify the main effects of psychological contracting in public organisations. We also aimed to collect fragmented academic knowledge produced by pertinent studies.

Methodology

This article adopts the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) approach to conduct the systematic literature review. The final sample of 41 empirical and conceptual studies were scientifically screened and synthesised.

Findings

This study establishes that a psychological contract is a complex phenomenon influencing individual, group, and organisational outcomes directly. The application of a systematic literature review demonstrates the importance of a psychological contract for public organisations. The review suggests an agenda for further research and identifies practical implications for public organisations.
Efficient fault identification scheme of compensated transmission grid based on correlated reactive power measurements and discrete wavelet transform
Authors: Zaki Mohamed I. , El-Sehiemy Ragab A. , Amer Ghada M.
Published: September 2021

The early fault identification in high-voltage power systems is a substantial aspect not only to minimize equipment failure but also to increase both the reliability and stability in power system. Subsequently, the aim of this paper is to propose the adaptive fault-identification scheme based on multi-resolution analysis technique. The proposed method is dependent on monitoring both voltages and currents from single-ended measuring system. The correlation among the reactive power computation and discrete wavelet transform is used to generate the significant criteria which are used to discriminate between short-circuit currents and energizing heavy loads behaviour. Different transmission network configurations are investigated to assess the dependability, security, and reliability of fault identification relay as well. The correlative protection scheme attains the accurate results under healthy disturbances, and therefore it is superior to other conventional approaches. In addition, a selective study is applied to different mother wavelets to find the best one. The response of the proposed scheme to the compensated transmission line is also verified at a wide range of compensation levels with faults before and after compensated bank. Simulation tests have been handled via ATP-EMTP to investigate the proper practicability and adaptability of the fault-identication relay.
Frequency domain despeckling technique for medical ultrasound images
Authors: Al-Asad Jawad F. , Mewada Hiren K. , Khan Adil H. , Abu-Libdeh Nidal , Nayfeh Jamal F.
Published: September 2021

This work proposes a novel frequency domain despeckling technique pertaining to the enhancement of the quality of medical ultrasound images. The results of the proposed method have been validated in comparison to both the time-domain and the frequency-domain projections of the schur decomposition as well as with several other benchmark schemes such as frost, lee, probabilistic non-local means (PNLM) and total variation filtering (TVF). The proposed algorithm has shown significant improvements in edge detection and signal to noise ratio (SNR) levels when compared with the performance of the other techniques. Both real and simulated medical ultrasound images have been used to evaluate the numerical and visual effects of each algorithm used in this work.
Design of dual-band implanted patch antenna system for bio-medical applications
Authors: Zaki Ahmed Z. A. , Abouelnaga Tamer Gaber , Hamad Ehab K. I. , Elsadek Hala A.
Published: September 2021

In this paper, a miniaturized implantable antenna system for biomedical applications is presented. The system consists of almost two similar patch antennas, named internal and external. The internal antenna is implanted inside the body at a depth of 2 mm, and the external antenna is to be attached to the body aligned with the internal one. The antenna system consists of implant-side antenna with dimensions are 10.25×10.25×1.27 mm3 , while the external antenna dimensions are 11.1×11.1×1.27 mm3. The proposed antennas designs showed dual resonant frequency on ISM bands (ie , 915 MHz and 2450 MHz
). The computed -10 dB bandwidth considering three-layer human phantom demonstrates that a bandwidth of 870 to 970 MHz and 2.38 to 2.47 GHz for internal and external antennas are achieved. The Specific Absorption Rate (SAR) has been considered for health care consideration. The measured and simulated scattering parameters are compared, and good agreements are achieved. The proposed antenna system is simulated and investigated for biomedical applications suitability.
Emphysematous osteomyelitis diagnosed on Tc99m MDP SPECT-CT scintigraphy: a case report
Authors: Gillani Farkhanda , Imran Muhammad Babar , Gill Owais Qadeer , Afzal4 Muhammad Shahzad
Published: September 2021

Background:

Emphysematous osteomyelitis is a rare but fatal condition, caused by gas-forming bacteria. We reported a rare case of emphysematous osteomyelitis of left femur in a 27-year-old diabetic male, diagnosed on Tc99m methylene diphosphonate (MDP) single photon emission computed tomography-computed tomography (SPECT-CT) scintigraphy. The pattern of uptake in emphysematous osteomyelitis on Tc99m MDP SPECT-CT scintigraphy was not reported previously.

Case Presentation:

A 27-year-old diabetic male patient presented with history of pain in left thigh and fever for 10 days. He was referred to nuclear medicine department for Tc99m MDP bone scan. He had no history of trauma or surgery, and his radiograph of left femur was unremarkable at presentation. Tc99m MDP SPECT-CT scintigraphy showed abnormal uptake in femur with intraosseous air, pathognomic of emphysematous osteomyelitis. Further imaging by magnetic resonant imaging (MRI) showed edematous changes in the musculature of left thigh with marrow replacement changes in left femur favoring the diagnosis of emphysematous osteomyelitis. However, no bacterial growth was detected on blood culture due to prior administration of intravenous antibiotics.

Conclusion:

Tc99m MDP SPECT-CT scintigraphy is helpful in diagnosis of such rare conditions like emphysematous osteomyelitis, in addition to common pathologies of bone. Furthermore, this report is helpful for nuclear physicians to know about the pattern of uptake on planner bone scan and SPECT-CT images in such a rare infection of bone, by gas forming bacteria.
AVICENNA’S CONTRIBUTION TO VASCULAR SURGERY
Authors:   Department of Surgical Diseases № 2, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan, GAIBOV A.D. , NEMATZODA O. ,   Republican Scientific Center for Cardiovascular Surgery, Dushanbe, Republic of Tajikistan, KALMYKOV E.L. ,   Vascular and Endovascular Surgery Clinic, Helios University Hospital, Wuppertal, Germany
Published: September 2021

The article reflects the main points of Avicenna’s contribution to vascular surgery. The scientist in his work described a very detailed pathogenesis of bleeding, the formation of a false aneurysm, thrombus formation in the venous system, and also the principles of their treatment, which was subsequently widely recognized by modern scientists. His great creation – «The Canon of Medicine» – contributed to the worldwide recognition of Avicenna both in the East and in the West. The role of Avicenna is also great in the development of pharmaceutical science and pharmacology. In particular, his main scientific ideas are still used to create modern medicines based on natural herbs and substances. Keywords: Abuali ibni Sino, Avicenna, history of medicine, vascular surgery, vascular injury, bleeding.
ASSESSMENT OF THE UFS-QOL QUESTIONNAIRE BEFORE AND AFTER UTERINE ARTERY EMBOLIZATION FOR UTERINE LEIOMYOMA
Authors:   Department of Endovascular Surgery, Republican Scientific Center for Cardiovascular Surgery, Dushanbe, Republic of Tajikistan, BARATOV A.K. , RAKHIMOV F.R. ,   Department of Surgical Diseases № 2, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan, KALMYKOV E.L. ,   Vascular and Endovascular Surgery Clinic, Helios University Hospital, Wuppertal, Germany
Published: September 2021

Objective: To assess of the quality of life before and after uterine artery embolization (UAE) for uterine leiomyoma. Methods: A survey of 15 women aged 23 to 47 years was conducted using the UFS-QOL questionnaire. The number of fibroids varied from 1 to 6. Fibroids were mainly localized: submucosal (53.3%), intramural (20%), and subserosal (26.7%). Their volume varied in the range of 25.04-294.09 ml. The dominant syndrome in 7 cases was hemorrhagic, in 7 – compression, and in 1 case – their combination. All women underwent UAE. The survey was conducted four times: before, 3, 6 and 12 months after UAE. Results: According to symptom severity subscale of the UFS-QOL questionnaire (8 questions), there was a significant improvement in symptoms 12 months after UAE in comparison with the baseline: a decrease of mean score from 43.3 to 14.0 (p<0.001). Analysis of the health related quality of life (HRQL) subscale (29 questions) also showed a significant improvement in the quality of life after 12 months compared to the initial level: an increase of mean score from 54.3 to 82.8 (p<0.001). The most significant dynamics (p<0.001) was noted for such domains «Concern», «Activities», «Energy/mood», and «Control» (p<0.001). The mean scores for the above domains increased from the baseline values 53.3±16.0; 56.4±18.4; 42.9±18.0 and 53.7±20.1 to 86.0±11.2; 86.9±11.6; 75.2±10.0 and 81.3±11.2 points after 12 months, respectively. For 2 other subsections of the HRQL «Self-consciousness» and «Sexual function», the mean score changes slightly differed: 67.2±32.2 and 71.7±32.9 (initially) and 85.0±12.3 and 86.7±22.4 (after 12 months) (p<0.05 and p<0.01, respectively). The total HRQL mean score also significantly (p<0.001) increased by month 12 from the baseline of 54.3±14.7 to 82.8±7.4. Conclusions: The UFS-QOL questionnaire is a very informative tool for assessing both the severity of the symptoms of uterine fibroids and the quality of life of women who underwent uterine artery embolization. According to the results of the UFS-QOL, a significant dynamics was obtained with respect to both the regression of symptoms of uterine fibroids, and the improvement of all parameters of the quality of life. Keywords: Uterine leiomyoma, uterine artery embolization, quality of life, UFS-QOL questionnaire.
EPIDEMIOLOGY OF THE PEDIATRIC EYE INJURIES IN THE SUGHD REGION OF TAJIKISTAN
Authors:   Department of Ophthalmology, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan, KARIM-ZADE KH.J. , OCHILZODA N.A. ,   Eye Department, Regional Clinical Hospital of Sughd Region, Khujand, Republic of Tajikistan, DADОBOEV Z.A. ,   Eye Department, Regional Clinical Hospital of Sughd Region, Khujand, Republic of Tajikistan
Published: September 2021

Objective: To study epidemiology and clinical features of of eye injuries in children in Sughd Region of the Republic of Tajikistan from 1993 up to 2013. Methods: A retrospective analysis of 616 (622 eyes) children with eye injuries required in-patient treatment in the Eye Department of Regional Clinical Hospital of Sughd Region was conducted for 20 years from 1993 to 2013. Results: For observable period in 616 children with eye injuries, who got in-patient treatment, the level of incidence was 6.6 per 100 000 children’s population of the region. Mean age was 7.7 (range from 1 to 15 years), male/female ratio was 2.8:1. Children aged 3-10 were most affected to injuries. Eye blunt trauma was diagnosed in 168 eyes (27%), open globe injuries in 429 (69%), eyelid injuries in 25 patients (4%). Visual acuity improvement (0.5-1.0) noted in 24.6%, moderate decrease of visual acuity (0.2-0.4) – in 12.9%, low vision (0.05-0.1) – in 7.9% and blindness (0-0.04) in 23% of cases. Factors, associated with unfavorable visual outcome were vitreous hemorrhage, hyphema, cataract and endophthalmitis. Conclusions: According to the results of the study, pediatric eye injuries are important causes of monocular blindness and impaired vision. In spite of improving possibilities of healthcare and treatment, in our study, one-third of children suffer from blindness and impaired vision, as a result of injuries, which indicates the need to develop and implement preventive and treatment measures in order to achieve the most favorable results of the injury. Keywords: Eye injury, children, Sughd Region, blindness, low vision.
HUMAN HERPES VIRUS TYPE 6 INFECTION IN CHILDREN AFTER ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION IN THE REPUBLIC OF BELARUS
Authors:   Belarusian Medical Academy of Postgraduate Education, Minsk, Republic of Belarus, KISHKURNO E.P. , AMVROSIEVA T.V. ,   Republican Research and Practical Center for Epidemiology and Microbiology, Minsk, Republic of Belarus, MAREYKO YU.E. ,   Republican Scientific Research Center for Pediatric Oncology, Hematology and Immunology, Minsk, Republic of Belarus, DIVAKOVA E.V. ,   Belarusian State Medical University, Minsk, Republic of Belarus
Published: September 2021

Objective: To evaluate the frequency of reactivation of HHV-6 infection in patients after allogeneic hematopoietic stem cell transplantation (allo-HSCT); determine viral load in serum/plasma and associated clinical manifestations; to determine the criteria for initiating anti-viral prophylaxis and etiotropic therapy in patients with this infection in the Republic of Belarus. Methods: Monitoring of polymerase chain reaction (PCR) of blood serum in 42 patients after allo-HSCT. Results: In 31% of patients, HHV-6 DNA was detected in serum/plasma on 14-28 days after allo-HSCT. The concentration of HHV-6 DNA in blood serum was up to 2.3-6.5×103 copies/ml, in 3 patients (18.8%) with the concentration of DNA≥2.3×103 copies/ml, developed clinical manifestations in the form of hepatitis. Regular monitoring of HHV-6 infection revealed reactivation of the infection and, with a viral load of≥100 copies/ml, initiate timely preventive treatment with ganciclovir. Conclusions: HHV-6 DNA is detected in one-third of patients after allo-HSCT and in the form of hepatitis. Timely prevention and therapy with ganciclovir reduce the risk of severe complications and fatal outcomes. Keywords: Children, HHV-6, hematology, stem cells transplantation, hepatitis.
EXPERIMENTAL STUDY OF INTEGRATION FEATURES OF POROUS PERMEABLE AND MESH TITANIUM NICKELIDE IN VIVO
Authors:   Department of Maxillofacial Surgery and Pediatric Dentistry, Institute of Postgraduate Education in Healthcare of the Republic of Tajikistan, Dushanbe, Republic of Tajikistan, MIRZOEV M.SH. , SHAKIROV M.N. ,   Department of Dentistry, Yaroslav-the-Wise Novgorod State University, Veliky Novgorod, Russian Federation, POROKHOVA E.D. ,   Department of Morphology and General Pathology, Siberian State Medical University, Tomsk, Russian Federation, DZHONIBEKOVA R.N. ,   Department of Maxillofacial Surgery, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan
Published: September 2021

Objective: Morphological assessment of the integration features of the combined use of porous permeable and textile mesh titanium nickelide with bone structures of the recipient zone. Methods: The study was carried out on 20 Chinchilla rabbits of both sexes at the age of 1-1.5 years with a bodyweight of 2500-4000 g. In animals, the artificial defect was created in one of the areas of the lower jaw, where a porous permeable titanium nickelide was installed, wrapped in a textile mesh version of it was installed. Animals were removed from the experiment for 30, 90, 180, and 360 days of research via intraperitoneal injection of mortal dose 1% solution thiopental sodium. The material for histological research was fixed in 10% buffered formalin during 12 hours after then washed with water and decalcified. The prepared sections were stained with hematoxylin-eosin. Microscopic examination of the stained preparations and photography were carried out using a light microscope Axioscope 40 (Zeiss, Germany) via a digital camera (Canon, Japan). Results: Studies have shown that with the combined use of porous permeable and textile mesh titanium nickelide, the artificially created defects of the mandibula between both contacting surfaces are formed directly, which leads to stable fixing. The porous structure of the material, its hysteresis behavior with organism tissues, provides widespread regeneration of cells and formed a homogeneous mature bone tissue bone tissue, both in the pores and around the structure. Conclusions: These and other facts indicate the high integration properties of the material that is investigated, which ensures optimal growth and population of osteogenic cells in the vicinity of defective bone areas in a growing organism. Keywords: Bone defect, osteointegration, regeneration, titanium nickelide, porous permeable implant.
ROLE OF MONOCYTES IN PATHOGENESIS OF GENERALIZED PERITONITIS
Authors:   Department of Surgical Diseases № 1, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan, SARAEV A.R. , NAZAROV SH.K. ,   Department of Surgical Diseases № 1, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan, ALI-ZADE S.G. ,   Department of Surgical Diseases № 1, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan
Published: September 2021

Objective: To study the sepsis markers informativeness to assess the role of monocytes in the pathogenesis of generalized peritonitis (GP). Methods: The study included 160 patients with GP, who were divided into 3 groups, according to the stages of the disease. To establish the activity of monocytes was made a determination of the level of cytokine TNF-α and presepsin in the blood. Results: Studies showed that the level of TNF-α in patient with septic shock was reliably lower (24.5±13.3 pg/ml) than in patients with endogenous intoxication and abdominal sepsis. The value of TNF-α in deceased patients also was low – 4.8±0.9 pg/ml. This indicates a decrease in the ability of monocytes in GP at the stage of septic shock to exude a sufficient amount of pro-inflammatory cytokines in response to endotoxin aggression. The level of presepsin increased by stages and amounted to 355.6±8.6, 783.4±24.0 and 1587.7±70.5 pg/ml, respectively. This indicates the circulation in the blood of the CD14 receptor, which is able to express on monocytes, converting them into endothelial progenitor cells. Conclusions: Monocytes as endothelial progenitor cells contribute to the regeneration and restoration of endothelial function in its dysfunction that develops in GP and abdominal sepsis. In consequence of developing immunosuppression and suppression of monocyte function in the stage of septic shock, the process of renewal of endothelial cells is weakened, the secretion of pro-inflammatory cytokines, in particular TNF-α, decreases, which can contribute to an increase in mortality in septic shock. Keywords: Monocytes, abdominal sepsis, septic shock, endothelial dysfunction, progenitor cells.
LASER PROSPECTS IN DENTISTRY AND MAXILLOFACIAL SURGERY
Authors:   Department of Maxillofacial Surgery and Surgical Dentistry, Kirov Military Medical Academy, Saint Petersburg, Russian Federation, CHERNEGOV V.V. , VASILIEVA L.V. ,   Department of Maxillofacial Surgery and Surgical Dentistry, Kirov Military Medical Academy, Saint Petersburg, Russian Federation, MITROFANOV A.A. ,   Department of Maxillofacial Surgery and Surgical Dentistry, Kirov Military Medical Academy, Saint Petersburg, Russian Federation, MITROFANOVA O.V. ,   Diagnostic Centre 7 (ophthalmic) for Adults and Children, Saint Petersburg, Russian Federation
Published: September 2021

The biomechanical parameters of laser radiation are complex and still insufficiently studied. A great number of studies are devoted to the laser’s actions on biological systems and tissues. It is considered that the findings of these studies form an almost independent field of knowledge. The major role in it plays the parts of clinical pathology. Description of action effects of laser radiation would not be considered credible without analyzing this direction. It is difficult to imagine progress in medicine without laser technologies that became modern assistants in solving many medical problems, by opening up new opportunities for us. The study of the mechanisms of action of laser radiation waves and energy levels on biological structures dictates the need for continuous improvement of laser medical multifunctional devices, the range of applications in clinical practice has become so broad that it is difficult to find a field of medicine where lasers are not used. Keywords: Lasers, picosecond laser, dentistry, maxillofacial surgery.
Competencia monopolística y externalidades en el criptomercado de drogas
Authors: Raffo Leonardo , Gómez-Calderón Diego , Ramírez-Andrade Carolina
Published: September 2021

El propósito de la investigación es explicar el funcionamiento y dinámica del criptomercado de drogas. Con ese propósito se desarrolló un modelo de competencia monopolística con externalidades en red basado en los trabajos Belleflamme y Peitz (2010) y Dixit y Stiglitz (1977). La principal predicción del modelo es que las políticas de interdicción en estos mercados tienden a ser contrarrestadas por la entrada de nuevos vendedores, y la resultante apertura de nuevas páginas web en la red oscura. Otro hallazgo es que, debido a la presencia de efectos de externalidad en red en el consumo de drogas online, el endurecimiento de las políticas de interdicción produce un efecto de retroalimentación que lleva a que a un mayor número efectivo de consumidores decida adquirir los dispositivos para acceder a las plataformas de drogas en la web oscura y, así, compre drogas ilegales.
Behaviour of Uniaxial Reinforced Concrete Columns Strengthened with Ultra-High Performance Concrete and Fiber Reinforced Polymers
Authors: Al-Hazragi Abd-al-Salam , Lateef Assim
Published: September 2021

This article investigates the behaviour of strengthened concrete columns using
jacketing ultra-high-performance fiber reinforced concrete (UHPFRC) and carbon
fiber-reinforced polymer (CFRP) under uniaxial loaded. The jacket was connected
to the column core using shear connectors and (CFRP) fixed as a strip on the
tension zone between the column cores and the jacketing. Seven column samples
of square cross-section (120 x120) mm at the midsection with overall length of
1250 mm were cast using normal strength concrete (NSC) and having similar
longitudinal and transverse reinforcement. The samples were made and tested
under axial load at eccentricity equal to 120 mm up to failure. Test parameters were
the thickness of jackets (25 and 35) mm and the width of CFRP (0,8, and 12) cm.
Column specimens were tested, one of them was reference without any
strengthening, and the other specimens divided into two groups (A, and B), and
each group included three specimens based on the parameters. Group (A) has
UHPFRC jacket thickness 25 mm and CFRP width (0,8, and 12) cm respectively,
and group (B) has UHPFRC jacket thickness 35 mm and CFRP width (0,8, and 12)
cm respectively. The outcomes of the article show that increasing the thickness of
jacket, and width of CFRP lead to increase in the load carrying capacity about
(110.5%,168.4%, and 184.2%) for group A, and (157.9%,226.3%, and 263.2%) for
group B compared with the reference column due to delay in the appearance of
cracks and their distribution. The mid-height lateral displacement of columns was
decreased about (66.6%,42.3%, and 35.9%) for group A, and (46.15%,38.46%, and
32.3%) for group B, also the axial deformation of specimens decreased about
(71.7%,60.86%, and 55.86%) for group A, and (65.5%,60.5%, and 53.4) for group
B compared with the reference column. The ductility of columns that were
strengthened with UHPFRC jacket only was increased about (13.67%,19.66%) for
thickness(25,35) mm respectively, because of that UHPFRC jacket was contented
on steel fibers, and the percentage decrease of ductility was about (5.1%,and 12%)
for group (A), (1%,and 9.4%) for group (B) when bonded CFRP in the tension zone
with width (8 ,and 12) cm respectively. The results show improvement in the initial
and secant stiffness when, increased the thickness of jacket, and width of CFRP
because of increase in the size of columns and improvement in the modulus of
elasticity. The toughness increase was about (273.97%,301.55%, and 304.5%) for
group A, and (453.69%,511.93%, and 524.28%) for group B compared with the
reference column because of increase in the size of specimens and delay the
appearance of cracks.
Object-Based Method for Urban Extraction through Using Quick Bird Satellite Imagery, LiDAR Data and Digital Urban Geomatics Techniques
Authors: Hamed Noor Hashim
Published: September 2021

Urban extraction mapping has become increasingly important in recent years and particularity extraction urban features based on remotely sensed data such as high-resolution imagery and LiDAR data. Though the researchers used the high spatial resolution image to extract urban area but he methods are still complexand still there are challenges associated with combining data that were acquired over differing time periods using inconsistent standards. So, this study will focus on the extraction of urban area based on an object-based classification method with integration of Quickbird satellite image and digital surface elevation (DSM) extracted from LiDAR data for the Rusafa city of Baghdad, Iraq. All the processes were done in eCognition and ArcGIS software for feature extraction and mapping, respectively. The overall methodological steps proposed in this research for the extraction of urban area using object-based method. In addition of that both the image data and LiDAR-derived DSM were integrated based on the eCognition software for extraction urban map of Rusafa city, Baghdad. Finally, the results indicated that the Artificial Neural Networks (ANN) model achieved the highest training and testing accuracies and performed the best compared to RF and Support Vector Machines (SVM) methods. And also, the results showed that the Artificial Neural Networks (ANN) had capability to extract the boundaries of the buildings and other urban features more accurately than the other two methods. This could be interpreted as the Artificial Neural Networks (ANN) model can learn complex features by the optimization process of the model and its multi-level feature extraction property.
How Trust Leads to Commitment on Microsourcing Platforms: Unraveling the Effects of Governance and Third-Party Mechanisms on Triadic Microsourcing Relationships
Authors:   Xi’an Jiaotong University, Guo Wenbo , Straub Detmar ,   Temple University, Zhang Pengzhu ,   Shanghai Jiao Tong University, Cai Zhao ,   University of Nottingham Ningbo China
Published: September 2021

IS research has extensively examined the role of trust in client-vendor relationships, as well as the role of governance in information technology (IT) outsourcing, but little research has been carried out on the latest manifestation of outsourcing—namely, microsourcing, i.e., the sourcing of smaller scale projects. To extend the literature on the traditional IT outsourcing literature—a stream that largely focuses on medium-to-large scale offline projects—we investigate how to develop trust and commitment in a triadic microsourcing relationship which includes the microsourcer, the microsourcee, and the microsourcing platform (MP). We draw on transaction cost economics (TCE) to theorize a model specifically adapted to the microsourcing phenomenon to scrutinize the influences of formal contractual mechanisms, relational mechanisms, and third-party mechanisms. Combining data from a matched sample of microsourcers and microsourcees on the leading Chinese MP, Zbj.com, the paper deploys degree-symmetric modeling (DSM) for construct conceptualization, measurement, and data analysis. DSM is consistent with the holistic view used to develop the research model for triadic relationships. Findings confirm that the MP is critical in delivering governance mechanisms to ensure the development of triadic trust and commitment. The results suggest that researchers and practitioners should pay closer attention to triadic trust and commitment building through proper governance mechanisms in the online microsourcing marketplace. We argue that this work could be extended to other online digital platforms that involve multiple transacting parties.
Information Technology Investment and Commercialized Innovation Performance: Dynamic Adjustment Costs and Curvilinear Impacts
Authors:   University of Hawai’i at Manoa, Karhade Prasanna , Qi Dong John ,   University of Dublin
Published: September 2021

Firms’ investment in information technology (IT) has been widely considered to be a key enabler of innovation. In this study, we integrate prior findings on the augmenting pathways (where IT investment supports innovation) with a new theory explaining the suppressing pathways (where dynamic adjustment costs associated with large IT investment can be detrimental to innovation) to propose an overall inverted U-shaped relationship between IT investment and commercialized innovation performance (CIP). To test our theory, we analyze a unique panel dataset from the largest economy in Europe and discovered a curvilinear relationship between IT investment and CIP for firms across a broad spectrum of industries. Our research presents empirical evidence corroborating the augmenting and suppressing pathways linking IT investment and CIP. Our findings serve as a cautionary signal to executives, discouraging overinvestment in IT.