bluuebunny/crossref_metadata_2025 huggingface dataset:
Trabajo y economía en una perspectiva sociologógica neo-institucionalista. Reflexiones acerca de 100 números de la revista Sociología del Trabajo
Authors: Pries Ludger
Published: July 2022

El mercado – como tipo ideal – es una institución social que rige en contextos de acción anónimos de intercambio de bienes, que son más o menos homogéneos, contables y cuantificables cuyo valor se determina por el tiempo de trabajo que cuesta fabricarlos. Históricamente, esta institución social del mercado, y del trabajo como vía central de participación social, se desarrolló tarde – por ejemplo a comparación de la institución de la familia o de la profesión – y mantuvo un peso marginal en la vida social de los seres humanos hasta el surgimiento del capitalismo moderno en el siglo XVIII y XIX. Hasta aquel entonces, el mercado era importante para comerciantes y esporádicamente para los campesinos o artesanos. Con respecto a la vida económica y del trabajo, más viejo que el mercado es la institución social de la red social, primordial y tradicionalmente en forma de la familia extendida y, hoy en día, también en forma de redes sociales secundarias. En el texto se esbozan brevemente las cinco instituciones sociales estructurantes de los campos organizacionales de economía y trabajo
Disputas sobre gênero e sexualidade: o papel de parlamentares progressistas na Câmara dos Deputados no Brasil
Authors: Mariano dos Santos Rayani
Published: July 2022

A Câmara dos Deputados tem presenciado uma ofensiva conservadora desde meados dos anos 2000 contra os direitos das mulheres e da população LGBTI+. Este artigo objetiva discutir como parlamentares progressistas atuaram no debate e tramitação de dois projetos de lei exemplificativos da disputa naquele espaço: o PL 6583/2013 (busca instituir o Estatuto da Família) e o PL 7180/2014 (relativo ao projeto Escola sem Partido). Foram analisados 294 discursos proferidos em plenário sobre os projetos, e 294 fichas relativas aos pronunciamentos nas comissões. A análise mostra que há parlamentares que atuaram de forma ativa nos dois projetos, indicando um comprometimento em relação à defesa desses direitos; e de que esses/as deputados/as são de partidos de esquerda. Além dos discursos, parlamentares fizeram manobras objetivando a não votação dos projetos, sendo bem-sucedidos no caso do Escola sem Partido, e sendo derrotados no que se refere ao Estatuto da Família, aprovado em 2015.
ANALISA PENGELOLAAN SAMPAH BERDASARKAN KETERSEDIAAN KENDARAAN OPERASIONAL DI KABUPATEN/KOTA DI PROVINSI JAWA BARAT
Authors: Rosmita Rosmita , Setyorini Dini
Published: July 2022

Salah satu faktor berhasil nya suatu daerah dalam pengelolaan sampah adalah ketersediaan kendaraan operasional dan sistem pengelolaannya. Masalah yang akan dibahas dalam penelitian ini adalah menganalisa ketersediaan kendaraan operasional sampah di kabupaten/kota di propinsi Jawa barat. Tujuan dari penelitian ini adalah untuk mengetahui apakah di kabupaten/kota di Jawa Barat sudah terpenuhi dan terkelola dengan baik sehingga tidak terjadi penumpukan sampah dimana mana sehingga kedepannya bisa ditingkatkan untuk mewujudkan Jawa Barat sebagai propinsi terbersih.

Data yang diambil dalam penelitian ini adalah data sekunder yang diambil dari BPS (Badan Pusat Statistik). Pengolahan data dilakukan dengan analisis varian. Dari data tabel analisis variansi nilai F hitung ? F tabel pada taraf 5% menunjukkan bahwa Ho diterima, artinya kendaraan operasional sampah yang disediakan oleh instansi yang bertanggung jawab dalam proses pengangkutan sampah mencukupi disetiap daerah.

Dalam hal penanggulangan sampah kedepannya diharapkan ada gebrakan pembaharuan pemanfaatan sampah sehingga sampah yang terbuang bisa di kurangi atau diminimalisir.
MANAJEMEN PENGAMBILAN KEPUTUSAN DALAM ORGANISASI
Authors: Saimo
Published: July 2022

Tujuan dari penulisan artikel ini yaitu mengetahui bagaimana manajemen pengambilan keputusan dalam organisasi. Penulisan artikel ini menggunakan metode studi literature review dari berbagai rujukan baik jurnal nasional maupun internasional. Pengambilan keputusan membutuhkan rangkaian proses terstruktur agar menghasilkan suatu perubahan terhadap organisasi ke arah yang lebih baik. Tahapan dalam pengambilan keputusan meliputi menetapkan tujuan dan sasaran, mengidentifikasi persoalan, mengembangkan dan menentukan alternatif, memilih satu alternatif, menerapkan keputusan serta pengendalian dan evaluasi. Pengambilan keputusan dapat dipengaruhi oleh beberapa faktor baik dari lingkungan internal atau eksternal.

Hasil dari penelitian menyatakan bahwa proses pengambilan keputusan dalam organisasi perlu memperhatikan tahapan yang akan dilalui, mengetahui model dan teknik pengambilan keputusan yang tepat untuk diterapkan, memperhatikan bias yang mungkin timbul serta faktor-faktor yang dapat memengaruhi pengambilan keputusan agar dapat menghasilkan keputusan yang baik dan mencapai tujuan organisasi.
PENINGKATAN HASIL BELAJAR MENULIS PUISI MELALUI PENDEKATAN PEMBELAJARAN CONTEXTUAL TEACHING AND LEARNING (CTL) PADA SISWA KELAS V SD NEGERI 68 KASSIJALA MAROS
Authors: Nurhasanah Nurhasanah , Yaba Yaba
Published: July 2022

Tujuan penelitian ini adalah untuk mengetahui apakah hasil belajar Bahasa Indonesia materi menulis puisi pada siswa kelas V dapat meningkat melalui penerapan pendekatan contextual teaching and learning (CTL). Penelitian ini adalah penelitian tindakan kelas (PTK). subjek penelitian adalah kelas V SD Negeri 68 Kassijala Maros, sebanyak 25 orang siswa yang terdiri dari 9 orang perempuan dan 16 orang laki-laki pada tahun pelajaran 2016/2017 semester genap. Data hasil observasi dianalisis secara kualitatif, sedangkan dari hasil kemampuan belajar siswa berupa pemberian tes, dianalisis secara kuantitatif.  Hasil penelitian menunjukkan adanya peningkatan hasil belajar siswa. pada siklus I nilai rata-rata mencapai 71 dengan persentase ketuntasan belajar 68%. Pada siklus II nilai rata-rata mencapai 79,25, mengalami peningkatan sebesar 8,25 poin dari siklus I dengan persentase ketuntasan belajar 92%. Berdasarkan data hasil belajar siklus I dan siklus II dapat disimpulkan bahwa pembelajaran sudah dianggap berhasil karena pada siklus II telah memenuhi kriteria ketuntasan belajar 75%. Dari hasil yang diperoleh, dapat diambil simpulan bahwa penggunaan pendekatan Contextual Teaching and Learning (CTL) dapat meningkatkan hasil belajar siswa
PENGGUNAAN MODELING KOGNITIF UNTUK MENGATASI KECEMASAN SISWA SAAT MENGERJAKAN TUGAS PADA MATA PELAJARAN IPA SDN NO.34 BIRORO KAB. SINJAI
Authors: Hafid Hafid , Hamid Sundari
Published: July 2022

Tujuan penelitian ini yaitu untuk mengetahui pengaruh penggunaan modeling kognitif untuk mengatasi kecemasan siswa saat mengerjakan tugas kelas pada mata pelajaran IPA di SDN NO. 34 Biroro. Penelitian ini menggunakan pendekatan eksperimen terhadap 8 subjek penelitian yang merupakan siswa kelas V di SDN NO.34 BIRORO Kabupaten Sinjai Pengumpulan data dengan menggunakan instrumen angket penelitian. Analisis data menggunakan analisis deskriptif. Hasil penelitian menunjukkan bahwa: (1) Tingkat kecemasan siswa saat mengerjakan tugas kelas pada mata pelajaran IPA di SDN NO.34 BIRORO Kabupaten Sinjai sebelum diberi modeling kognitif berada pada kategori tinggi, namun setelah diberi modeling kognitif  yang meliputi tujuh tahap, maka tingkat kecemasan siswa saat mengerjakan tugas kelas pada mata pelajaran IPA mengalami penurunan atau berada pada kategori rendah, dan (2) Terdapat  perbedaan tingkat kecemasan siswa saat mengerjakan tugas kelas pada mata pelajaran IPA sebelum dan sesudah diberi modeling kognitif. Artinya bila modeling kognitif  diterapkan, maka dapat membantu menurunkan kecemasan siswa dalam mengerjakan tugas kelas pada mata pelajaran IPA di SDN NO.34 BIRORO Kabupaten Sinjai
Ergenlerde Akademik Dayanıklılık ve Okul Tükenmişliğiyle Başa Çıkma Becerisi Arasındaki İlişkinin İncelenmesi
Authors: GÜNDOĞAN Selim
Published: July 2022

Okul tükenmişliği eğitim süreci devam eden her öğrencide belli dönemlerde görülebilen ve birtakım olumsuzluklarayol açan bir durumdur. Bu yüzden öğrencilerin okul tükenmişliğiyle başa çıkabilme becerilerine odaklanmanınönemli bir konu olduğu ifade edilebilir. Bu bağlamda bu çalışmada ergenlerin akademik dayanıklılıkları ile okultükenmişliğiyle başa çıkma becerisi arasındaki ilişki ele alınmıştır. Çalışmanın katılımcı grubu lise eğitiminedevam eden yaşları 13 ile 18 arasında olan 272 (%65) kız ve 146 (%35) erkek olmak üzere toplam 418 ergen bireydenoluşmaktadır. Çalışmanın verileri okul tükenmişliğiyle başa çıkma becerisi ölçeği ve akademik dayanıklılık ölçeğiile toplanmıştır. Verilerin analizinde korelasyon ve regresyon analizi kullanılmıştır. Korelasyon analizi sonucundaakademik dayanıklılık ve okul tükenmişliğiyle başa çıkma becerisinin üç alt boyutu arasında istatistiksel olarakanlamlı ilişkiler bulunmuştur. Regresyon analizi sonucunda ise akademik dayanıklılığın okul tükenmişliğiyle başaçıkma becerisinin üç alt boyutunun da anlamlı bir yordayıcısı olduğu sonucuna ulaşılmıştır. Çalışmada ulaşılanbulgular literatür doğrultusunda tartışılmış, araştırmacılar ve uygulayıcılar için öneriler sunulmuştur.
A comprehensive case review of microbial remediation of heavy metals and pesticides in Yamuna River
Authors: Raghav Nupur , Sharma Shweta , SIngh Parul , Yadav Sanjay , Nigam Rajesh
Published: July 2022

Water resources (mainly surface and groundwater) support two-thirds of the global population but have been of great concern in recent years. Most civilizations all around the world evolved on the river's banks. River Yamuna is the major tributary to River Ganga (India’s largest river) and one of the major rivers in India. The extreme cause of pollution in rivers is the excessive discharge of domestic waste water from adjacent towns and residents, contributing to about two-thirds of pollution. Agricultural and industrial effluents cause the rest one-third. Organic pollutants can be treated or removed through appropriate sewage water treatment before final discharge into the river. The status of river water is advantageous because it determines the life cycle of animals, plants, and human beings. The direct use of river water for drinking causes severe hazards due to anthropogenic activities causing environmental pollution in rivers. The noxious discharge of toxic industrial waste consisting of heavy metals and pesticides into the water bodies, especially rivers, prevails in water bodies and accumulates through the food chain. Biomagnification of toxic heavy metals and pesticides through the food chain causes severe health hazards to humans and other living creatures. However, extensive farming depends on pesticides, accelerating water and land contamination. Long-duration contact with pesticides can harm living organisms and disrupt the function of different body organs. Various chemical and biological methods are available for reducing the water pollution level. Still, the emergence of an astonishing technology of multi-cultures of aerobic and anaerobic effective and beneficial microorganisms is gaining popularity because of its eco-friendly nature.
Stability indicating LC-MS Method development and Validation for Quantitative analysis of Pimozide
Authors: Naidu Gorripati Ch Rama , Chintakula Sudhakar , Rao Battula Sreenivasa , Kalyani J.V.S.K.V.
Published: July 2022

The objective of the current investigation is to study the degradation behaviour of the Pimozide under different stress conditions using LC-MS method. Pimozide is a diphenyl butylpiperidine derivative used as antipsychotic drug. It was exposed to different stress conditions like acidic, alkali, thermal, peroxide and UV light to investigate its stability. Successful separation of drug from its degradation products was achieved on Waters C18 column (150mm X 4.5mm, 5µm) using methanol and acetonitrile 65:35 (V/V) having pH 5.5 as mobile phase in isocratic elution mode at a flow rate of 1.0ml/min with UV detection at 230nm. Quantification was achieved using an electrospray ion interface operating in positive mode, under multiple reaction monitoring conditions. Optimized LC-MS conditions were validated by ICH Q2 (R1) guidelines with respect to specificity, precision, linearity, recovery, LOD and LOQ. The method proved that Pimozide was found sensitive under UV light and alkali conditions, stable under thermal stress condition and moderate stability under acidic and oxidation condition with lowest degradation. The developed LC-MS method was found simple, sensitive and efficiently separated the drug and its degradation products in all samples.
Extraction and Preconcentration of Cd (II) by using Crown Ether DB18C6
Authors: Majeed Hameed Safa , Sabah Abdulwahid Marwa
Published: July 2022

Extracted Cd(II) as (CdCl3-) and (CdCl42-) from HCl media after preparing ion pair complexes according to liquid ion exchange method by using DB18C6 after changing to liquid ion exchanger K-Crown+; Cl-, spectrophotometric studies showed that the extracted ion pair complex had a wave length for maximum absorbance of λmax=277nm. Limitations to the study include optimum conditions for extraction in this study show a need for 0.3M HCl, to be present 50µg for Cd(II), in addition to study extracted complex structure by Slope ratio method, the result appear more probable structure of extracted complex [K DB18C6]+;HCdCl4- and [K-DB18C6]+; CdCl3-. This method applied to spectrophotometric determination of Cd(II) in different sample and compare the results with atomic absorption spectroscopy.
Impact on HDL and LDL of Hyperlipidemic Rat Models: Designed Solid Self-Nanoemulsifying Drug Delivery Systems with Atorvastatin and Ezetimibe combination
Authors: R. Gardouh Ahmed , M. Nasef Ahmed , Mostafa Yasser , Gad Shadeed
Published: July 2022

The main purpose of this study was to develop and evaluate solid self-nanoemulsifying drug delivery systems (S-SNEDDs) of Atorvastatin/ Ezetimibe combination to combine the advantages of liquid SNEDDs with those of solid dosage forms and investigate the effect of solidification on both lipid lowering efficiency and the ability to enhance oral bioavailability of included poorly water soluble drugs. Spray dried solid powder was prepared using Aerosil 200 based on its high adsorption capacity and the ratio of liquid SNEDDs: Aerosil was (4:1) due to the smaller droplet size produced after reconstitution compared to other ratios. Surface morphology characteristics and drug-excipients interactions were evaluated via Scanning Electron Microscopy (SEM) and Fourier Transformed Infrared Spectroscopy (FTIR). Crystallinity nature affect drug dissolution so, it was determined by Differential Scanning Calorimetry (DSC) and Powder X-ray Diffraction (PXRD). Pharmacokinetic study investigated the ability of (S-SNEDDS) to improve oral bioavailability of included drugs while, pharmacodynamic study evaluate its efficiency to control serum cholesterol levels compared to pure drugs suspension and liquid SNEDDs. Solid spray dried powder showed very good flowability (3.41±0.23g/s) and rapid dispersion in water with maintaining the self-emulsifying efficiency of liquid formula. Physicochemical evaluation of powder showed spherical separated particles with no significant drug-excipients interactions and drugs are molecularly dispersed or in amorphous state that improve dissolution rate as proven by in-vitro release studies. Pharmacokinetic and pharmacodynamic studies proved that the solidification process had no remarkable effect on the efficiency of liquid formula to enhance oral bioavailability of incorporated drugs and control serum cholesterol level compared to pure drugs suspension. S-SNEDDS was proved as efficient candidate to improve oral bioavailability of Atorvastatin / Ezetimibe combination and control cholesterol serum levels.
Development and Validation of UV Spectrophotometric Method of Pirenzepine Dihydrochloride in API and Stress Degradation Studies
Authors: Rajmane Archana , Trivedi Rahul , Nandgude Tanaji
Published: July 2022

A simple, accurate, precise spectrophotometric method was developed for the detection of Pirenzepine dihydrochloride (PZC). The optimum condition for the analysis of the drug was studied. PZC was subjected to stress degradation under different conditions like acidic, alkali, neutral, oxidation, photolytic, and thermal degradation as per recommended by the International Conference on Harmonization (ICH). The samples thus prepared were used for degradation studies by with the developed method. The lambda max i.e. absorption maxima found at 281nm and calibration curve linear over the range of 0-20µg/ml. The standard regression equation and correlation coefficient fond to be y = 0.04x + 0.056 R² = 0.998 respectively. Percent RSD found to be less than one. The accepted limits of accuracy (recovery) were found to be 90% - 120% and all observed data are within required range which indicates good recovery value. and LOD and LOQ found to be 0.165 and 0.500 respectively by simple UV spectroscopy.
Research on the Teaching Reform of “Inter- Professional Comprehensive Training” Based on the BOPPPS Model under the Background of New Business
Authors: Lai Weidong
Published: July 2022

With the development of new technologies such as the Internet, cloud computing, artificial intelligence, and big data, new business models and new industrial forms have emerged. The demand for talents is also rapidly increasing across industries. This also puts forward new requirements for the cultivation of business talents and the reform of business teaching mode. “Inter-professional comprehensive training” is a highly applied course. By simulating real job content, business process, business documents, etc., students’ job skills, professional quality, business decision-making ability and innovation ability are cultivated. This paper analyzes the development of inter-professional comprehensive training in Z school, analyzes its existing problems, and proposes, among other things, targeted teaching reform suggestions, so as to provide reference for schools that carry out relevant courses.
Being a Trainer for Psychotherapy – the Beginning of a New Career
Authors: Hum Gabriela
Published: July 2022

The article is a recommendation for those who want to become trainers, about what it means to work with groups and what are the prerequisites and responsibilities of a trainer. It is detailed based on the author’s experience of over 20 years as a trainer and her work as WAPP assessor, between 2019 – 2021. It can be a good guide for those who want to become trainers in the future.
How Do Traditional Stories Work in the Process of Solving Unconscious, Interpersonal and Cultural Conflict? A Contribution to Narrative Ethics
Authors: Remmers Arno
Published: July 2022

Fairy tales, narratives and proverbs are cultural carriers of tradition, development pattern and values. Even if they are the same over a long time, they gain their own new meaning in new situations. Creation myths, classical legends or the repeated basic patterns and archetypes of fairy tales and children’s songs are collective models of understanding. The great psychotherapeutic themes of self-employment, conscience formation, the triangulation conflict, or the threshold situation can be found in them. Narratives used in therapy and counseling depict social norms by which readers or listeners can measure their own belief; on the other hand, they question norms, especially by exaggerating them, and invite people to question their own. The dilemma of the inner conflict, the ‘am-bi-valence’ in value conflicts, the tragedy of experience can often become more understandable in a story than in logical explanations. The patient – therapist – history triangle provides a further dimension of transmission, relieves the dual relationship in its interrelationship, allows both to look together at something third. In literature research the background of narrative therapy is compared with the experiences.
Quality Assessment Of Information On Retinal Detachment On YouTube Videos
Authors: ÇETİNKAYA YAPRAK Aslı , AKTAŞ Emine Hazal
Published: July 2022

Objective: This study evaluated the quality, reliability and effectiveness of YouTube videos addressing retinal detachment.

Material and Methods:An online search of YouTube was performed using the keyword retinal detachment and the first 100 videos were included in the study. All videos were evaluated numbers of likes, dislikes, comments, view, daily viewing rate, uploaded source (physicians, public/private institution, or health channel), country of origin, video type (patient experience, scholarly information), and contents (clinic, treatment or both of them), Journal of the American Medical Association (JAMA), DISCERN, global quality (GQS) and usefulness scores by two independent ophthalmologists.

Results:Eighty eight videos of the top 100 videos met the criteria. The mean DISCERN, JAMA, GQS and usefulness score were 44.81 ± 14, 1.66 ± 0.58, 2.81 ± 0.93 and 2.05 ± 1.24, respectively. 52 (59.1%) videos were uploded by physicians and 36 (40.9%) videos were uploded by non-physicians. In the correlation analysis, the all scoring systems showed a significant and strong positive correlation with each other (p
Dosimetric Examination of Out-of-Field Doses with TLD in Breast Irradiation with Different Radiotherapy Techniques
Authors: BAŞARAN Hamit , GÜL Osman Vefa , İNAN Gökçen
Published: July 2022

Öz

Amaç: Bu çalışmada meme kanseri nedeniyle radyoterapi alan gerçek hastayı taklit eden bir fantom üzerinde farklı organlarda absorbe edilen doz araştırılmıştır. Farklı organlardaki ortalama doz için tedavi planlama sistemi (TPS) ve termolüminesans dozimetre (TLD) doz ölçümleri karşılaştırılmıştır.

Gereç ve Yöntemler: Alderson kadın rando fantom üzerinde sol meme dokusu hedef tedavi hacmi olarak seçildi. Varian DHX cihazında farklı tedavi teknikleri ile yapılmış uygulamalara özel tedavi planları belirlendi (3DCRT, 5 Alan- IMRT, 7 Alan- IMRT). Fantomda belirlenen hacim içindeki yerlere TLD-100 dozimetreleri yerleştirildikten sonra ışınlandı. Daha sonra her bir teknik için elde edilen doz ölçümleri TPS dozları ile karşılaştırıldı.

Bulgular: 3DCRT, 5 Alan- IMRT ve 7 Alan- IMRT tekniklerinde planlanan hedef volümün (PTV) ortalama doz değeri için TPS dozları ve TLD dozları arasındaki istatistiksel anlamlılık sırasıyla, p=0.042, p=0.002 ve p=0.030 olarak bulunmuştur. Tiroid’in ortalama dozunda IMRT tekniği ile yapılan planlarda TPS ve TLD dozları arasındaki farkın arttığı görülmüştür. Fetüs dozları incelendiğinde TPS ile doz saptanmazken TLD ile ortalama fetüs dozu 3.13-16.87 cGy olarak bulunmuştur. Ayrıca parotis dozları incelendiğinde TPS ile doz saptanmazken TLD ile ortalama parotis dozu 10.37- 57.75 cGy olarak ölçülmüştür.

Sonuç: TPS’in 8 cm’den uzak mesafelerde organ dozlarını tahmin etmede başarısız olduğu söylenebilir. Meme radyoterapisinde 3DCRT tedavi tekniğinin tercih edilmesi daha avantajlı olacaktır.

Anahtar Kelimeler: Termolüminesans dozimetre, Meme radyoterapi, Alan dışı doz
Prediyaliz Kronik Böbrek Hastalığında bitkisel ilaç kullanımının değerlendirilmesi
Authors: BORA Feyza , ASAR Emine , AVŞAR Esin , SÖZEL Hasan , YILMAZ Fatih
Published: July 2022

Z
Amaç
Kronik böbrek hastalığı (KBH) nedenlerinden biri nefrotoksik bitkisel ürünler olabilir. Bu çalışma, KBH hastalarında bitkisel ürün kullanım oranı, kullanılan ürünler, tedarik kaynakları, bu ürünlerle akut böbrek yetmezliği gelişip gelişmediği ve bu alanda prediyaliz eğitiminin yerini tespit etmek amacıyla yapıldı.
Gereç ve Yöntemler
Nefroloji bölümünde 209 hastanın verileri toplandı ve bir prediyaliz eğitim hemşiresi tarafından bire bir hasta görüşmeleriyle doldurulan eğitim formu kullanılarak retrospektif olarak değerlendirildi.
Bulgular
Hastaların yaş ortalaması 57,3 yıl, % 41'i kadındı. Hastaların % 22’si (n=45) bitkisel ürünler kullanmıştı. Stabil glomerül filtrasyon hızı ile takip edilen yedi hastada bitkisel ürünler kullandıktan sonra akut böbrek hasarı atakları yaşandığı tespit edildi. Hastaların kullandıkları bitkisel ürün isimleri şunlardı: bilinmeyen ot karışımı , siyah kimyon yağı, kiraz sapı, biberiye, tarçın, Helichrysum Arenarium, kaynak suyu, Galyum aparine, reishi mantarı, Ceratonia siliqua, papatya, salyangoz kabuğu, Viburnum opulus, soğan suyu, Sstevia redianadon Bertion, malus trilobata yaprağı, avokado yaprağı, incir ve zeytin yaprağı, at kestanesi, zencefil, cevizi suda bekletip elde edilen su, kabak çekirdeği, Vitex agnus-castus, aloe vera, yaban mersini, ardıç pekmezi, Equisetum arvense L, Lamii albi herba1, yoğurt suyu idi. Altı aydan uzun süre takip edilen hastalar bitkisel ürünleri, diğer hastalardan daha fazla kullanma eğilimindeydiler (p = 0.08).
Sonuç
Bitkisel ürün kullanımınının yaygınlaşması nedeniyle, klinisyenler hastaların bitkisel ürünlerin kullanımı konusunda daha dikkatli olmalıdırlar.
Anahtar kelimeler: Kronik Böbrek Hastalığı, Bitkisel İlaç, Eğitim, İletişim
The Role of P53 Gene Mutation Detected in Bile Fluid in the Diagnosis and Determining Prognosis of Patients with Extrahepatic Cholangiocarcinoma
Authors: DENLER KILIÇ Arzu , KOÇKAR Muhammed Cem , AKIN Mete , ASLAN KOŞAR Pınar , ŞAHİN CALAPOĞLU Nilüfer
Published: July 2022

ÖZ

Ekstrahepatik Kolanjiokarsinomalı Hastalarda Safra Sıvısında Tespit Edilen P53 Gen Mutasyonunun Tanı ve Prognozu Belirlemedeki Rolü

Amaç: Günümüzde yeni tanısal tekniklerin ortaya çıkmasına rağmen ekstrahepatik kolanjiokarsinoma tanısını koymak ve cerrahi öncesi değerlendirmesini yapmak oldukça güçtür. Bu çalışmada ekstrahepatik kolanjiokarsinoma tanısı konulan hastalarda safra sıvısında P53 gen mutasyonun araştırılması ve bunun tanı ve prognozu belirlemede yol gösterici olup olamayacağının belirlenmesi amaçlanmıştır.
Yöntem: Çalışmaya ekstrahepatik kolanjiokarsinoma tanısı konulan 40 hasta ve kontrol gurubu olarak da malignite dışı nedenlerle endoskopik retrograd kolanjiopankreatografi (ERCP) yapılmış olan 40 hasta alındı. Bu hastaların ERCP sırasında alınan safra sıvılarında p53 tümör supresör geninin ekson 5 ve 8 nolu kodonlarında mutasyon araştırıldı.
Bulgular: Kolanjiokarsinomalı hastalardan oluşan grupta safra sıvısında p53 geninin 5. eksonunda 4 adet, 8. eksonunda 2 adet mutasyon saptanıldı. Malign ve Bening gruplar karşılaştırıldığında mutasyonun varlığı açısından ekson 5’in 34007064 nolu ve 65389650 nolu kodonu ile ekson 8 in 78378222 nolu ve 35659787 nolu kodonunda anlamlı farklılık olduğu görüldü (p < 0,05).
Sonuç: Bu çalışmada ekstrahepatik kolanjiokarsinomalı olgularda safra sıvısında p53 geninde ekson 5-8 de daha önce tanımlanmamış mutasyonlar tanımlanmıştır. Bu mutasyonların hepsinin klinikte kullanımında tanı koymaya yetmeceği, ancak tanıyı kuvvetlendirici bir kriter olabileceği düşünülmüştür.
Anahtar kelimeler: Ekstrahepatik kolanjiokarsinoma, P53 gen mutasyonu, Safra sıvısı, Endoskopik retrograd kolanjiopankreatografi
EVALUATION OF VITAMIN D RECEPTOR LEVEL IN HEMATOPOETIC CELLS AND INFLAMMATORY MARKERS IN STAGE 3-5 CHRONIC RENAL PATIENTS
Authors: YAZDAN BALÇIK Onur , BORA Feyza , KÖKSOY Sadi , ERSOY Fettah Fevzi
Published: July 2022

ÖZ:
Amaç: Bu çalışmada, evre 3-5 Kronik böbrek hastalarında (KBH) vitamin D replasmanının CD3+, CD4+, CD8+ ve CD14+ hematopoietik hücre alt gruplarındaki vitamin D reseptör (VDR) yüzdesi ile inflamatuar belirteçlerle ilişkisini değerlendirmeyi amaçladık.
Yöntem:
Bu prospektif çalışmada evre 3-5 KBH’sı olan; tahmini glomerüler filtrasyon hızı (tGFH) ≤60ml/dk/1,73m2 olan 81 hasta katıldı. Serum kreatinin, tGFH, intakt parathormon (iPTH), 25 OH vitamin D düzeyleri, CRP, nötrofil, lenfosit değerleri ve CD3+, CD4+, CD8+, CD14+ hematopoietik hücrelerde VDR yüzdeleri hesaplandı. Hastalar, 25 OH VD3 düzeylerine göre Vitamin D eksikliği tanısıyla (<20 ve ≥20 ng/dl) iki gruba, KBH evrelerine göre (evre 3-5) üç gruba, D vitamini kullanımı durumuna göre (kullanmıyor, kalsitriol veya 25 OH vitamin D) üç gruba ayrıldı.
Bulgular:
Vitamin D eksikliği tanısıyla iki gruba ayrılan hastalarda aktif D vitamini kullanımı, kreatinin, tGFH ve iPTH düzeyleri arasında istatistiksel anlamda fark tespit edildi (p:0,04, p:0,008, p:0,02 ve p:0,002). CRP ve nötrofil /lenfosit oranı arasında istatistiksel fark tespit edilmedi (p:0,95, p:0,63). Hastaları KBH evrelerine göre gruplandırdığımızda iPTH düzeylerinde istatistiksel fark tespit edildi (p:0,001). Hastaları D vitamini kullanımı durumuna göre üç gruba ayırdığımızda kreatinin, tGFH, iPTH ve 25 OH vitamin D3 düzeyleri arasında istatistiksel fark tespit edildi (p:0,00, p:0,00, p: 0,02 ve p:0,006). CD3 +, CD4 +, CD8 +, CD14 + hematopoietik hücrelerde VDR yüzdeleri arasında bir fark tespit edilmedi (p:0,17, p:0,15, p:0,14, p:0,31). Lenfosit düzeyleriyle tGFH değerleri arasında istatistiksel bir korelasyon vardı (r:0,28, p:0,011). Lenfosit düzeyleriyle CD8+ hücrelerin VDR yüzdesi değerleri arasında istatistiksel bir korelasyon vardı (r:0,224, p:0,046).
Sonuç: Replasman tedavileri ile VDR yüzdelerinin tüm evrelerde benzer oranlarda tutulabileceği, inflamasyonda azalma sağlanmış olabileceğinden kaynaklı olabilir.
ANAHTAR KELİMELER: İnflamasyon, Kronik Böbrek Hastalığı, Vitamin D, Vitamin D Reseptör Düzeyi
Fetal Left Acheiria in Levetiracetam Use During Pregnancy: A Case Report
Authors: KANDEMİR Hülya , SANHAL Cem Yaşar , SAKINCI Mehmet
Published: July 2022

Öz:
Epilepsi, üreme çağındaki kadınlarda görülen yaygın kronik hastalıklardan biridir. Epileptik nöbet geçirmenin ciddi maternal ve fetal riskleri vardır, bu nedenle gebelikte tedaviye devam etmek gerekir. Konjenital malformasyon (KM) oranları özellikle birinci kuşak antiepileptik kullanımı ile artmaktadır. Levetirasetam (LEV) ise ikinci kuşak antiepileptik olup, teratojenik yan etkileri daha azdır. LEV kullanan gebede KM ile ilgili yayınlar olmasına rağmen, bu ilaca özgü herhangi bir malformasyon bildirilmemiştir. Biz gebeliği boyunca LEV kullanan ve fetüste sol el yokluğu (acheiria) izlenen bir vakayı bildirmekteyiz.
Anahtar Kelimeler:Konjenital malformasyon, Fetal el yokluğu, Levetirasetam, Antiepileptik ilaç
REMOVAL OF AMMONIA EFFLUENT FROM ABR BYCONSTRUCTED WETLANDS
Authors: MARSONO BOWO DJOKO , VOIJAN BIEBY
Published: July 2022

Communal domestic wastewater treatment plant has been widely built in the area in Indonesia. The government through the Ministry of Public Works and Public Housing with several programs has built a Communal IPAL in almost all districts in Indonesia. Domestic wastewater treatment generally uses ABR (Anaerobic Baffle Reactor) technology. Domestic wastewater treatment with ABR can reduce organic carbon and total suspended solid concentration but less effective in reducing ammonia. ABR has a bod seed and efficiency of BOD 80%, COD 90%, TSS 70% and Ammonia 20%. The presence of Ammonia in the receiving water body will lead to decreasing oxygen levels and eutrophication. Applied phytotechnology can be a solution to overcome effluent levels in ABR as long as there is sufficient land. Research has been conducted that the efficiency of ammonia reduction in Wetland reached 76%.
EFFECT OF AMMONIA AND COD TO SULFATE RATIO ONTREATMENT PERFORMANCE OF CONCENTRATED LATEXPROCESSING WASTEWATER
Authors: JAWJIT SIRIUMA , JAWJIT WARIT
Published: July 2022

The objective of this study is to investigate the effects of ammonia nitrogen (NH3-N) and COD to sulfate ratio on the treatment performance of concentrated latex processing wastewater (CLPW). In a batch experiment, the CLPW influent COD, % granular sludge and pH were controlled at about1,200 mg/l, 10% and 7, respectively. The influent NH3-N concentrations varied at 100, 500, 1000 and3000 mg/l, whereas COD/sulfate ratio varied at 0.3, 0.6, 1 and 1.3. Treatment performance was determined by methane generation rate and COD removal efficiency at different NH3-N and COD to sulfate ratio. The NH3-N concentration at 100 and 500 mg/l (which were presented in the real CLPW), did not result in inhibition on methane producing bacteria (MPB), since methane generation was detected. Inhibition on MPB was observed at 1,000 mg/l NH3-N. Strong inhibition occurred at 3,000 mg/l NH3-N, since % COD removal was relatively reduced to 7.98 % and nomethane generation. The COD/sulfate ratio at lower than 0.6 resulted in inhibition of MPB, but in the real CLPW the ratio is normally higher than 0.6. Ammonia concentration higher than 1000 mg/l and COD to Sulfate at lower than 0.6 resulted in inhibition of methane producing bacteria in the treatment of CLPW.
A STUDY TOWARDS THE REALIZATION OF GREEN TECHNOLOGYIN URBAN WATER SUPPLY SECTOR WITH LIFE CYCLEASSESSMENT (LCA) METHOD AND FAULT TREE ANALYSIS (FTA) METHOD
Authors: KARNANINGROEM NIEKE , MARDYANTO MAS AGUS , BRAMANTI GEODITA WORO , ANGGRAENI DESY RISQI
Published: July 2022

Water Treatment Plant (WTP) with conventional systems use pumps that work for 24 hours, andchemicals which produce residues or by products in water processing and have an impact on the environment and humans. This study aims to identify the quality and performance of the WTP treatment, Identify the impacts arising from the drinking water treatment process and determine the efforts made to reduce the impacts identified by the method Life Cycle Assessment (LCA). The Life Cycle Assessment (LCA) method is an assessment method regarding potential environmental impacts and evaluation of the environmental performance of a process to the product. Life Cycle Assessment (LCA) consists of four stages, consist of determinations Goal and Scope, Life Cycle Inventory, Life Cycle Impact Assessment, data interpretation. The software used in Sima Pro 9.0.0with the impact assessment method is CML-IA Baseline. The impacts discussed in this research are Global Warming, Human Toxicity, and Eutrophication. The way to reduce the impact based on literature studies. The results of the analysis found that the quality of raw water has not reach the quality standards as drinking water standards. While the quality of produced water has reach the quality standard. The performance of the processing unit at WTP has not worked well, need improvement with the addition of polymer in clearator, electricity usage in WTP is11.220.195,47kWh/year. The analysis results using Life Cycle Assessment (LCA) method, showed that the highest contribution to environmental impact was Eutrophication of 287.644,1 kg PO4âeq/year followed by Global Warming of 23.697.275 kg CO2eq/year, and Human Toxicity of 9.190.241 kg1,4-DBeq/year. The way to reduce the impact is take pretreatment on raw water, planning and build sludge treatment, also recycle sludge from clearator unit, replace equipment, replace aluminum sulfate, and liquid chlorine into PAC and hypochlorite salts.
STUDY OF RISK MINIMIZATION UTILIZATION OF BOTTLEDWATER BY CONSUMERS USING HAZARD ANALYSIS CRITICALCONTROL POINT (HACCP) AND EXTENDED PRODUCERRESPONSIBILITY (EPR) METHODS
Authors: MARDYANTO MAS AGUS , KARNANINGROEM NIEKE , PRADANA ADHITIA SATRIA
Published: July 2022

The demand for drinking water in Cirebon City is increasing and is not proportional to the drinking water supply capacity of DWTP (PDAM) Cirebon City. So the Bottled Water Company was established, which is engaged in bottled water company, whose production rate continues to increase. The need for quality control methods to improve the quality of bottled drinking water products that can affect the quality of products consumed by the customers. Bottled Water Company applies the HACCP and EPR methods which aim to evaluate the performance of the bottled water production processing unit in planning quality control with the HACCP method, determine the quality control of bottled drinking water products to minimize negative risks to consumers with the EPR method, and compare the quality of freshly produced bottled water with products that consumers accept. Based on the analysis of existing conditions on the Bottled Water Company, the poor performance of the processing unit and the need for quality control monitoring is caused by replacing the membrane, cartridge micro filter and ozone generator, the ozone injection unit that exceeds the usage limit, poor quality of raw water pumps and back wash scheduling of carbon filter media affect the quality of production water and products. Quality control using the EPR method is carried out on the use of raw materials, production processes, finished products, product storage and distribution, sanitation and waste treatment, and product quality to consumers. Changes and decreases in product quality are due to the distance between the delivery to the store, the shipping or transportation process, the method of storage, and the length of time the product is stored.
THE IMPORTANT ROLE OF AG AND CU ON ENHANCINGDECHLORINATION OF 2,4-DICHLOROPHENOL BY AG/CU/FENANOPARTICLES: PERFORMANCE STUDY
Authors: ZHANG WENBIN , LIU CAN , LIU LANYU , CHEN JUN , GAO FEI
Published: July 2022

In this paper, polyvinylpyrrolidone-stabilized Ag/Cu/Fe polymetallic composites were successfully prepared by liquid-phase reduction method and characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM) and Vibration magnetometer (VSM) detection means thatthe crystal structure of the material, surface morphology, Magnetic properties and group changes. The catalytic degradation of chlorinated phenolic organic pollutants, such as 2,4-dichlorophenolin water was studied initially discussed the Ag/Cu/Fe NPs removal of 2,4-dichlorophenol catalyticreduction mechanism and kinetic model. The results show that PVP has good stability to Ag/Cu/Fe NPs. The particle size of Ag/Cu/Fe modified by PVP is small, and it is uniformly dispersed inalcohol aqueous solution and cannot be easily agglomerated. Fast and efficient separation, with excellent recycling performance, PVP stabilized Ag/Cu/Fe NPs for 2,4-dichlorophenol catalyticdegradation has a good effect. The degradation of 2,4-dichlorophenol by Ag/Cu/Fe NPs accords with quasi-first-order kinetic model.
DETERMINANTS OF SEASONAL VARIATIONS IN SURFACEOZONE – A STUDY IN VISAKHAPATNAM CITY OFANDHRA PRADESH, INDIA
Authors: CHANDU KAVITHA , A. DHARMA RAJU , KUMAR S.V. J. , PATRO SUDARSHAN
Published: July 2022

Ozone is an important constituent of the atmosphere. It is a variable gas and even a minute changes in its composition in the vertical profile of the atmospheric gases can cause far reaching implications vis-Ã -vis warming of the earth and other effects. About 90% of Ozone is found in the stratosphere up to 50km the majority of which is in the height range of 10-16 km. The stratosphericozone protects the earth from the harmful effects of the Ultraviolet (UV) radiation and hence it is known as âgood ozoneâ. The remaining 10% of ozone in the atmosphere hovers in the troposphere and resides on the ground which is a pollutant that is harmful to plants, animals, and humans. This is bad ozone. Hence, Ozone is metaphorically referred to as, âGood up high but bad down belowâ. The paper attempts to analyze the seasonal variation in concentration of ozone at the surface. The role of precursors that help in formation and destruction are studied. The study shows correlation of concentration of surface ozone with precursors. The statistical inferences show an irrefutable influence of meteorological parameters on the concentration of ozone.
INFLUENCE OF BENTHIC FAUNA ON HYDROCHEMISTRY ANDSEDIMENT IN SASTHAMKOTTA LAKE IN SOUTHERN KERALA, INDIA
Authors: MURALI S. MUNISHA , SHEEBA S.
Published: July 2022

Sasthamkotta Lake is the largest freshwater water body of Kerala with great ecological significance, playing also pivotal role in the supply of water for drinking, agriculture, fishery exploitation, industrial activities, frivolous navigation and water tourism. Due to their importance, the environmental conditions in the Sasthamkotta lake have engrossed an better public attention in present society. The concentrations of various physico-chemical parameters of water and sediment are not exceeding environmental standards. Benthic samples revealed 8 species belonging to Order Diptera, Order Trichoptera and Order Tubificida. The results obtained from the study showed good ecological condition despite numerous local and regional natural and anthropogenic interventions.
IMPACT OF SEASONAL VARIATION ON UNDERGROUND WATERQUALITY IN BBN AREA, HIMACHAL PRADESH, INDIA
Authors: RANA VISHAL , WALIA YOGESH KUMAR , GAUTAM DIVYA , SETHI VANDANA
Published: July 2022

The present investigation was carried out in BBN (Baddi-Baroutiwala-Nalagharh) area of Solan districtof Himachal Pradesh. The sources, Hand pumps and bore wells taken for the sampling ofunderground water in this study area. This study of underground water is focused on seasonalvariation of the quality of groundwater and level of pollution in underground water sources inBBN area. The analysis of physico-chemical parameters of six sampling stations during April, 2018to December, (2018). Parameters such as Temperature, pH, turbidity, Total alkalinity, Total Dissolved Solids (TDS), sodium, cadmium, copper, iron, lead etc. The analysis results were carried out according to APHA, 2012 procedures. The results obtained have been compared with BIS standards for drinking water (BIS: IS: 10500, 2012). The result revealed that the concentration of mostly physico-chemical parameters found higher in monsoon season as compared to summer and winter seasons. The assessment shows that underground water of this area is not suitable for drinking purpose without purification. Domestic sewage and Chemicals or industrial effluents are the main responsible factors for quality degradation of underground water in the BBN area.
RATIO DERIVATIVE SPECTROPHOTOMETRIC MONITORING AND PHYTOREMEDIATION OF PANTOPRAZOLE
Authors: MUKHERJEE SOMA , DHAR SUPARNA , PATHAK SUBHANKAR , HAQUE MONAMI
Published: July 2022

Recently much attention has been placed to identify the presence of emerging contaminants with special reference to pharmaceutical wastes by the development of specific techniques for detection and monitoring of environmental pollutants at the trace level. The present work aims to investigate the application of a non-destructive, selective and less expensive ratio derivative spectrophotometric method for the monitoring of pantoprazole present in the pharmaceutical binary mixture and wastewater without their prior separation. The linear calibration curve was obtained in the concentration range of 1.0-75.0 ppm for pantoprazole (r2 = 0.994). It was found that significant amounts of pantoprazole can be recovered from laboratory prepared binary mixtures (98.73 %, 100.69 % and 103.46 %), distilled water (98.90 %, 100.13 % and 94.57 %) and wastewater (103.60 %, 98.38 % and 104.73 %) via spike method with known concentrations (40.0 ppm, 50.0 ppm and 60.0 ppm respectively) of pharmaceuticals viz. omeprazole and pantoprazole. Interestingly, selected macrophytes (water hyacinth and water lettuce) were capable to remove pantoprazole (~60 %) from waste water samples.
A REVIEW OF MODERN TECHNOLOGIES FOR REDUCTION OFDIOXINS AND FURANS FROM FLUE GAS EMISSIONS OFBIOMEDICAL WASTE INCINERATORS IN INDIAN PERSPECTIVE
Authors: VERMA SANDEEP KUMAR , SINGH N.B. , TRIPATHI C.N
Published: July 2022

The present paper discusses the mechanism of formation of dioxins and furans and the technologies used to mitigate the formation of such chemical compounds during the combustion process. By reviewing the findings of several investigations, being conducted by several researchers for the last 30 years, it has been found that the formation of Dioxins and Furans canbe considerably reduced by using the chemical compounds which function as catalysts. Such catalysts are vanadium pentaoxide V2O5, Tungsten Trioxide WO3, and Titanium dioxide TIO2. Besides, there are some sulphur compounds which inhibit the formation of dioxins and furans. Such compounds are Sulphur dioxide SO2 and ammonium sulphate (NH4)2 SO4. There are some Thiourea chemicals which play an important role in inhibiting the formation of dioxins and furans. Such chemical compounds are Ethanolamine C2H7NO, Urea CH4N2O, Mono ethanolamine (H2NCH2CH2OH) etc. But the greatest drawback in the aforesaid technologies is that, they require heavy capital cost as well as the high operating cost. As a solution to the problems, some German companies have developed the techniques for recovering HCl, Nacl and SO2 which are marketable and thus, can make the process cost- effective. Another solution is to adopt a good combustion practice by modifying the design of combustion chambers (primary and secondary) as per guidelines issued by CPCB, India (2017). Lastly it may be considered to switch over to the latest alternative technology of Plasma Pyrolysis which provides a complete solution to the problem. The objective of the present study is to help the stakeholders in the process of making decisions and opting for the latest technologies for a pollution free environment.
HUBUNGAN ANTARA MOTIVASI BELAJAR MATEMATIKA DENGAN LITERASI NUMERASI SISWA KELAS V SEKOLAH DASAR NEGERI UTAN KAYU SELATAN KECAMATAN MATRAMAN JAKARTA TIMUR
Authors: Hasibuan Ida Lestari , Nafiah Maratun , Supriatna A. R.
Published: July 2022

Penelitian ini bertujuan untuk mengetahui hubungan antara motivasi belajar matematika dengan literasi numerasi siswa kelas V Sekolah Dasar Negeri Utan Kayu Selatan Kecamatan Matraman Jakarta Timur. Waktu pelaksanaan penelitian yaitu pada bulan Januari hingga Juni tahun 2021 di kelas V Sekolah Dasar. Pengumpulan data dilakukan dengan menggunakan angket motivasi belajar matematika dan tes literasi numerasi kepada 87 siswa sebagai sampel penelitian. Data tersebut kemudian dihitung normalitas menggunakan Uji Liliefors dan homogenitas dengan Varian F hitung memperoleh keterangan bahwa data berdistribusi normal dan homogen. Selanjutnya data diolah dan dianalisis menggunakan korelasi Product Moment menunjukkan nilai r sebesar 0,217 dan Uji-t menunjukkan thitung (2,045) lebih besar daripada ttabel (1,663). Berdasarkan hasil tersebut maka dapat disimpulkan bahwa terdapat hubungan yang positif dan signifikan antara motivasi belajar matematika dengan literasi numerasi siswa kelas V SD Negeri Utan Kayu Selatan Kecamatan Matraman Jakarta Timur.
Pengembangan Augmented Reality-Based Geometry Book (Ar-Geo) Untuk Meningkatkan Kemampuan Spasial pada Pembelajaran Materi Geometri 3-D.
Authors: Ismayani Ani
Published: July 2022

Penelitian dan pengembangan (Research & Development) ini dilakukan dengan tujuan untuk mengembangkan produk yang bernama “AR-Geo”, yaitu buku ajar berbasis Augmented Reality (AR), dan implementasinya dalam meningkatkan kemampuan spasial siswa pada pembelajaran matematika materi 3-dimensi (3-D). Langkah-langkah penelitian yang ditempuh menggunakan model 4-D dengan tahapan: (1) define (pendefinisian), (2) design (perancangan), (3) develop (pengembangan), dan (4) disseminate (penyebaran), tujuannya adalah agar produk yang dihasilkan benar-benar valid dan dinyatakan efektif digunakan dalam pembelajaran di kelas.      

 Kata kunci: Penelitian dan Pengembangan (R&D), AR-Geo, Augmented Reality (AR), kemampuan spasial, model 4-D.