bluuebunny/crossref_metadata_2025 huggingface dataset:
Communication with patients with limited prognosis—an integrative mixed-methods evaluation study
Authors: Siegle Anja , Unsöld Laura , Deis Nicole , Krug Katja , Bossert Jasmin , Krisam Johannes , Jung Corinna , Jünger Jana , Wensing Michel , Thomas Michael , Villalobos Matthias
Published: December 2022

Purpose

Oncological societies advocate the continuity of care, specialized communication, and early integration of palliative care. To comply with these recommendations, an interprofessional, longitudinally-structured communication concept, the Milestone Communication Approach (MCA), was previously developed, implemented, and evaluated. Our research question is: what are possible explanations from the patient perspective for prognosis and advance care planning being rarely a topic and for finding no differences between MCA and control groups concerning distress, quality of life, and mood?

Methods

A pragmatic epistemological stance guided the study. A mixed-methods design was chosen including a pragmatic randomized trial (n = 171), qualitative interviews with patients (n = 13) and caregivers (n = 12), and a content analysis (133 milestone conversations, 54 follow-up calls). Data analysis involved the pillar integration process.

Results

Two pillar themes emerged: 1 “approaching prognosis and advance care planning”; 2 “living with a life-threatening illness”. Information on prognosis seemed to be offered, but patients’ reactions were diverse. Some patients have to deal with having advanced lung cancer while nonetheless feeling healthy and seem not to be ready for prognostic information. All patients seemed to struggle to preserve their quality of life and keep distress under control.

Conclusion

Attending to patients’ questions, worries and needs early in a disease trajectory seems key to helping patients adjust to living with lung cancer. If necessary clinicians should name their predicament: having to inform about prognosis versus respecting the patients wish to avoid it. Research should support better understanding of patients not wishing for prognostic information to successfully improve communication strategies.

Trial registration

Registration: German Clinical Trial Register No. DRKS00013649, registration date 12/22/2017, (https://www.drks.de/drks_web/navigate.do?navigationId=trial.HTML&TRIAL_ID=DRKS00013649) and No. DRKS00013469, registration date 12/22/2017, (https://www.drks.de/drks_web/navigate.do?navigationId=trial.HTML&TRIAL_ID=DRKS00013469).
Entrainment Rates and Their Synoptic Dependence on Wind Speed Aloft in California's Central Valley
Authors: Caputi Dani J. , Trousdell Justin , Mehrotra Shobhit , Conley Stephen , Alexander G. Aaron , Oldroyd Holly J. , Faloona Ian
Published: December 2022

Daytime atmospheric boundary layer (ABL) dynamics—including potential temperature budgets, water vapour budgets, and entrainment rates—are presented from in situ flight data taken on six afternoons near Fresno in the San Joaquin Valley (SJV) of California during July/August 2016. The flights took place as a part of the California Baseline Ozone Transport Study aimed at investigating transport pathways of air entering the Central Valley from offshore and mixing down to the surface. Midday entrainment velocity estimates ranged from 0.8 to 5.4 cm s−1 and were derived from a combination of continuously determined ABL heights during each flight and model-derived subsidence rates, which averaged -2.0 cm s−1 in the flight region. A strong correlation was found between entrainment velocity (normalized by the convective velocity scale) and an inverse bulk ABL Richardson number, suggesting that wind shear at the ABL top plays a significant role in driving entrainment. Similarly, we found a strong correlation between the entrainment efficiency (the ratio of entrainment to surface heat fluxes with an average of 0.23 ± 0.15) and the wind speed at the ABL top. We explore the synoptic conditions that generate higher winds near the ABL top and propose that warm anomalies in the southern Sierra Nevada mountains promote increased entrainment. Additionally, a method is outlined to estimate turbulence kinetic energy, convective velocity scale (w*), and the surface sensible heat flux in the ABL from a slow, airborne wind measurement system using mixed-layer similarity theory.
Identifying Genes that Affect Differentiation of Human Neural Stem Cells and Myelination of Mature Oligodendrocytes
Authors: Ye Dou , Wang Qian , Yang Yinxiang , Chen Bingyu , Zhang Fan , Wang Zhaoyan , Luan Zuo
Published: December 2022

Human neural stem cells (NSCs) are self-renewing, multipotent cells of the central nervous system (CNS). They are characterized by their ability to differentiate into a range of cells, including oligodendrocytes (OLs), neurons, and astrocytes, depending on exogenous stimuli. An efficient and easy directional differentiation method was developed for obtaining large quantities of high-quality of human OL progenitor cells (OPCs) and OLs from NSCs. RNA sequencing, immunofluorescence staining, flow cytometry, western blot, label-free proteomic sequencing, and qPCR were performed in OL lines differentiated from NSC lines. The changes in the positive rate of typical proteins were analyzed expressed by NSCs, neurons, astrocytes, OPCs, and OLs. We assessed Gene Ontology (GO) enrichment and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways of differentially expressed (DE) messenger RNAs (mRNAs) related to the differentiation of NSCs and the maturation of OLs. The percentage of NSCs differentiated into neurons, astrocytes, and OLs was 82.13%, 80.19%, and 90.15%, respectively. We found that nestin, PAX6, Musashi, and vimentin were highly expressed in NSCs; PDGFR-α, A2B5, NG2, OLIG2, SOX10, and NKX2-2 were highly expressed in OPCs; and CNP, GALC, PLP1, and MBP were highly expressed in OLs. RNA sequencing, western blot and qPCR revealed that ERBB4 and SORL1 gradually increased during NSC–OL differentiation. In conclusion, NSCs can differentiate into neurons, astrocytes, and OLs efficiently. PDGFR-α, APC, ID4, PLLP, and other markers were related to NSC differentiation and OL maturation. Moreover, we refined a screening method for ERBB4 and SORL1, which may underlie NSC differentiation and OL maturation.

Graphical Abstract

Potential unreported genes and proteins may regulate differentiation of human neural stem cells into oligodendrocyte lineage. Neural stem cells (NSCs) can differentiate into neurons, astrocytes, and oligodendrocyte (OLs) efficiently. By analyzing the DE mRNAs and proteins of NSCs and OLs lineage, we could identify reported markers and unreported markers of ERBB4 and SORL1 that may underlie regulate NSC differentiation and OL maturation.
Interplay between Safety Climate and Emotional Exhaustion: Effects on First Responders’ Safety Behavior and Wellbeing Over Time
Authors: Lee Jin , Resick Christian J. , Allen Joseph A. , Davis Andrea L. , Taylor Jennifer A.
Published: December 2022

Various job demands continuously threaten Emergency Medical Service (EMS) first responders’ safety and wellbeing. Drawing on Job Demands–Resources Theory, the present study examines the effects of the organizational context—safety climate—and the psychological context—emotional exhaustion—on safety behaviors and wellbeing over time. We tested our hypotheses in a longitudinal study of 208 EMS first responders nested within 45 stations from three fire departments in US metropolitan areas over 6 months during the beginning of the COVID-19 pandemic. Multilevel modeling showed that the relationship between safety climate and safety compliance behaviors can be attenuated when EMS first responders experience high emotional exhaustion. Emotional exhaustion was also negatively associated with morale while safety climate was positively associated with morale. Additionally, EMS first responders experienced increased depression when their emotional exhaustion levels were high. Higher safety climate was associated with decreased depression when emotional exhaustion was within a low-to-medium range. Higher safety climate was also associated with lower absolute levels of depression across the entire range of emotional exhaustion. These findings suggest that promoting safety climate and mitigating emotional exhaustion can augment EMS first responders’ safety behaviors and wellbeing.]
High-energy two-electron transfer in ion-atom collisions
Authors: Belkić Dževad
Published: December 2022

Two-electron transfer by fast heavy nuclei from heliumlike targets is studied. A detailed sequence of comprehensive computations is carried out in a large keV–MeV range of the projectile energies. This set is illustrated with total cross sections for double capture by alpha particles from helium atoms using several frequently applied four-body quantum-mechanical distorted wave models with the correct boundary conditions. The sensitivity of the obtained total cross sections is examined for different choices of the bound and continuum states. Especially at high energies, the influence of the compactness of the bound states is investigated by reference to the mechanism of the velocity matching kinematic double electron capture. Also considered is the dependence of these cross sections on the electronic screening of the projectile and the target nuclear charges in the bound and continuum states. The impact of this electronic shielding on total cross sections is assessed by reference to the corresponding bare nuclear charges in the bound and continuum states. Relative to all the available experimental data (100–6000 keV), the found striking model-dependence implies that two-electron transfer is sharply different from the associated one-electron transfer involving the same colliding particles.
Towards a typology of risk preference: Four risk profiles describe two-thirds of individuals in a large sample of the U.S. population
Authors: Frey Renato , Duncan Shannon M. , Weber Elke U.
Published: December 2022

It has been a longstanding goal of the behavioral sciences to measure and model people’s risk preferences. In this article, we adopt a novel theoretical perspective of doing so and test to what extent specific types of individuals share similar risk profiles (i.e., configurations of multidimensional risk preferences). To this end, we analyzed data of a U.S. sample (N = 3,123) in a comprehensive and rigorous way, resulting in a twofold contribution. First, based on data from the Domain-Specific Risk-Taking scale (DOSPERT) and using a cross-validation procedure, we established a multidimensional trait space including general and domain-specific dimensions of risk preference. Second, we employed model-based cluster analyses in this multidimensional trait space, finding that 66% of participants can be described well with four basic risk profiles. In sum, the typological perspective proposed in this article has important implications for current theories of risk preference and the measurement of individual differences therein.
Parametric Analysis and Optimization of Vanillin Hydrodeoxygenation Over a Sulfided Ni-Mo/δ-Al2O3 Catalyst Under Continuous-Flow Conditions
Authors: Kristensen Tove , Hulteberg Christian , Blomberg Sara , Tunå Per , Abdelaziz Omar
Published: December 2022

A fundamental understanding of the process parameters affecting the catalytic hydrodeoxygenation (HDO) of bio-oils is of significance for enabling further progression and improvement of industrial biofuel upgrading methods. Herein, a novel demonstration and evaluation of the effect of temperature, pressure, and weight hourly space velocity in the continuous HDO of vanillin to cresol over a Ni-Mo/δ-Al2O3 catalyst are presented. Response surface methodology was used as a statistical experimental design method, and the application of central composite design enabled the generation of a statistically significant simulation model and a true optimization parametric study. The distribution of Ni and Mo on δ-Al2O3 was confirmed using scanning electron microscopy with energy dispersive X-ray analysis (SEM-EDX). No gradients with EDX mapping could be identified, and the elemental analysis showed well-dispersion of the metals. The mesoporous character of the catalyst-support system was unraveled using N2 physisorption. Experiments were conducted within the parametric range of 250–350 °C, 3–9 bar, and 15–35 h−1. Both temperature and pressure were found to have statistically significant linear and quadratic effects on the selectivity for cresol. The parametric interaction of temperature with pressure and space velocity also had a significant effect on the resulting response. The optimal temperature range becomes more critical at lower space velocities. Optimal selectivity for cresol was established at 314 °C, 5 bar, and 35 h−1. The fitting quality of the generated regression model was statistically confirmed and experimentally validated to describe the specified HDO process within the 95% two-sided confidence interval.
Mapping potential surpluses, deficits, and mismatches of ecosystem services supply and demand for urban areas
Authors: Vargas Leonardo , Ruiz Diana , Gómez-Navarro Carolina , Ramirez Wilson , Hernandez Olga Lucia
Published: December 2022

Land-use decision making in densely populated cities is challenged to cover the urban demand for water and food while maintaining the integrity of ecosystems that regulate the supply of these ecosystem services, beyond urban limits. Land-use decision making can be informed using spatial analysis of ecosystem services supply and demand, shedding light on potential mismatches, surpluses, deficits, and unsustainable uses of ecosystems. The integration of such analysis in land-use decision making, however, can be challenged by the complexity of the hierarchical and inflexible planning models used in various countries. We explored how the analysis of potential mismatches, surpluses, and deficits in the supply and demand of water and fertile soil can be spatially assessed for urban areas, and how such information can be used to inform land-use decision making. We used official data and geoprocessing methods to map water -supply, demand, and risk for water scarcity-, and fertile supply –supply, demand, and risk for food insecurity-, for Bogota and Villavicencio. We showed a high risk for water scarcity in Bogota, and an increasing competition for fertile soil between urbanization and agriculture. We recommended a cooperative management strategy of ecosystems and services considering that both cities shared river basins and natural reserves, in addition to their strike differences in population size. Inter-jurisdictional and inter-municipal cooperation, in addition to strong governance, are necessary to handle mismatches of urban ecosystem services supply and demand, and a potential solution to solve conflicts related to access, availability, and jurisdiction of ecosystem services in urban areas.

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Understanding Potato Production Practices in North-Western Kenya through Surveys: an Important Key to Improving Production
Authors: Kwambai Thomas K. , Struik Paul C. , Griffin Denis , Stack Laura , Rono Selly , Nyongesa Moses , Brophy Caroline , Gorman Monica
Published: December 2022

Potato is the second most important food crop after maize in Kenya. However, most farmers produce potatoes under sub-optimal management, resulting in low yields, despite the introduction of improved varieties. Potato production practices were documented and compared to contribute towards improved potato management and productivity in Kenya. The study was guided by the hypothesis that potato farming and management practices influence potato performance and can depend on the production environment. Focus group discussions and household surveys were conducted in three major potato growing areas in Kaptama, Saboti and Lelan in Bungoma, Trans Nzoia and Elgeyo Marakwet counties in Kenya. Farming was the main occupation of 58.2% of the respondents. Respondents across the study sites indicated that they grew potatoes with their main focus as a cash (83.6%) and food (16.4%) crop. Most respondents had planted potatoes during both the last long (96.4%) and short (92.4%) rainy seasons. The four most important constraints limiting optimal potato production according to respondents were lack of quality seed, diseases (specifically late blight and bacterial wilt), poor marketing and lack of adequate technical knowledge on potato management. Low yields realized by farmers were mainly influenced by poor farmer practices in the use of seed, fertilizers, pesticides and crop rotation. This was compounded by farmers’ perceptions on input quantities applied, frequencies and farmers’ access to agricultural extension information on potatoes, which heavily relied on family members and neighbouring farmers. Provision of quality seeds and training of farmers with the support of demonstrations on fertilizer and pesticide and appropriate crop rotation practices are recommended for improved potato production and yields. Use of irrigation where possible should be enhanced through government and development partners’ support to ensure sustainable potato production and supply. Also, the use of viable extension information channel(s) could enhance potato production for household food security, livelihoods and national goals.
Phantom study on surgical performance in augmented reality laparoscopy
Authors: Heiliger Christian , Heiliger Thomas , Deodati Alessandra , Winkler Alexander , Grimm Matthias , Kalim Faisal , Esteban Javier , Mihatsch Lorenz , Hiendl Lena , Andrade Dorian , Frank Alexander , Jacob Sven , Mohamed Khaled Ahmed , Solyanik Olga , Mandal Subhamoy , Werner Jens , Eck Ulrich , Navab Nassir , Karcz Konrad
Published: December 2022

Purpose

Only a few studies have evaluated Augmented Reality (AR) in in vivo simulations compared to traditional laparoscopy; further research is especially needed regarding the most effective AR visualization technique. This pilot study aims to determine, under controlled conditions on a 3D-printed phantom, whether an AR laparoscope improves surgical outcomes over conventional laparoscopy without augmentation.

Methods

We selected six surgical residents at a similar level of training and had them perform a laparoscopic task. The participants repeated the experiment three times, using different 3D phantoms and visualizations:Floating AR,Occlusion AR, and without any AR visualization (Control). Surgical performance was determined using objective measurements. Subjective measures, such as task load and potential application areas, were collected with questionnaires.

Results

Differences in operative time, total touching time, and SurgTLX scores showed no statistical significance ($$p>0.05$$p>0.05). However, when assessing the invasiveness of the simulated intervention, the comparison revealed a statistically significant difference ($$p=0.009$$p=0.009). Participants felt AR could be useful for various surgeries, especially for liver, sigmoid, and pancreatic resections (100%). Almost all participants agreed that AR could potentially lead to improved surgical parameters, such as operative time (83%), complication rate (83%), and identifying risk structures (83%).

Conclusion

According to our results, AR may have great potential in visceral surgery and based on the objective measures of the study, may improve surgeons' performance in terms of an atraumatic approach. In this pilot study, participants consistently took more time to complete the task, had more contact with the vascular tree, were significantly more invasive, and scored higher on the SurgTLX survey than with AR.
Corrosion Behavior of EN18 Steel and Copper in the Sulfuric Acid Medium for As-Bought and Annealed Materials
Authors: Jomy Jilna , Sharma Sathyashankara , Prabhu P. R. , Prabhu Deepa
Published: December 2022

EN18 steel and copper are used as materials for oil and gas industries for chemical storage, which come in contact with the sulfuric acid medium during the pickling process. In such instances cleaning of impurities and oxide layer removal, leads to excessive corrosion. Thus, the improvement in the microstructure through annealing treatment and its effect on the corrosion behavior of EN18 steel and copper are studied by immersing in 0.5 M H2SO4 for as-bought and 0.5, 0.25, 0.1 M H2SO4 medium solutions after annealing treatment. The metal specimens were heated to 900 °C for EN18 steel and 600 °C for copper and then both were furnace cooled and the change in the microstructure of annealed and as-received metal specimens was analyzed using Scanning Electron microscopy (SEM). The Electrochemical Impedance Spectroscopy (EIS) and Potentiodynamic polarization (PDP) measurement showed that there is a decrease in the corrosion rate for both metals after annealing treatment. The effect of corrosion rate at the temperature range of 30-50 °C was analyzed and activation parameters were described using Arrhenius and transition state theories. Suitable corrosion mechanisms for both steel and copper in the H2SO4 medium have been discussed.
Graph-based prediction of missing KPIs through optimization and random forests for KPI systems
Authors: May Marvin Carl , Fang Zeyu , Eitel Michael B. M. , Stricker Nicole , Ghoshdastidar Debarghya , Lanza Gisela
Published: December 2022

Key performance indicators (KPIs) are widely used to monitor and control the production in industry. On an aggregated level, often represented as graphs or interrelated KPI systems, a comprehensive overview is given. However, missing or inaccurate sensor data and KPIs, as well inconsistencies in KPI based management are a major hurdle disturbing operations. To counter the impact of such missing KPIs, we propose a value optimization based approach to reconstruct the values of missing KPIs within a KPI system. While the approach shows successful reconstruction in the case study, the value optimization can be sped up through a random forest prediction of the initial optimization set. Thus, the inclusion of previous knowledge about the system behavior proves beneficial and superior to the pure optimization based approach, as validated by both randomized and simulation-based measurement data.
Wood Hemicelluloses as Innovative Wall Materials for Spray-Dried Microencapsulation of Berry Juice: Part 1—Effect of Homogenization Techniques on their Feed Solution Properties
Authors: Halahlah Abedalghani , Piironen Vieno , Mikkonen Kirsi S. , Ho Thao M.
Published: December 2022

The use of wood hemicelluloses, including galactoglucomannans (GGM) and glucuronoxylans (GX), in spray-dried microencapsulation of bioactive compounds has not been reported. Our study aims to investigate the benefits of spray-dried GGM and GX powders (sGGM and sGX) along with the effects of homogenization techniques (magnetic stirring, ultrasonication, and a combination of UltraTurrax homogenization and microfluidization) on the physicochemical properties of feed solutions (10–20%, w/w). Feed solutions of bilberry juice with sGGM, sGX, and mixtures of either sGGM or sGX with methylcellulose (MC) or carboxymethylcellulose (CMC) were examined to produce highly stable feed solutions for spray-dried microencapsulation. The effects of ultrasonication amplitudes (30–80%) on the viscosity and particle size distribution of sGGM feed solutions were more profound than observed in their sGX counterparts. Unlike sGX feed solutions, sGGM feed solutions homogenized by ultrasonication and microfluidization formed a gel-like structure. Microfluidization also caused a loss of total anthocyanin content (TAC) of the feed solutions. Magnetic stirring resulted in no gel formation and in the lowest viscosity of the feed solutions; hence, it is an effective method for preparing hemicellulose feed solutions. sGGM and sGX powders have high heat stability with melting temperatures of 170–180 °C. The sGGM + CMC combination was more stable over 1 week of storage than the sGGM and sGX feed solutions. Storing the feed solutions reduced TAC and increased sGGM viscosity. Our results indicated that GGM and GX have high potential for use as wall materials in the spray-dried microencapsulation of bioactive compounds.
Effect of Temporarily Opening and Closing the Marine Connection of a River Estuary
Authors: Montagna Paul A. , Palmer Terence A. , Pollack Jennifer Beseres
Published: December 2022

The lower Rio Grande is a river-dominated estuary that serves as the border between Texas, USA, and Tamaulipas, Mexico. River estuaries encompass the section of the river influenced by tidal exchange with the Gulf of Mexico, but the connection with the Rio Grande is intermittent and can be temporarily open or closed. During the 4.8-year study period, the river mouth was closed 30% of the time, mostly during average or dry climatic conditions, with the temporary closing of the river mouth being linked to hydrology. When the Rio Grande estuary is closed, salinity is low (1.5 psu compared to 4.8 psu when open), nitrate plus nitrite are low (4.4 μM compared to 31.5 μM when open), and ammonium is high (9.6 μM compared to 4.3 μM when open), but chlorophyll is similar (20 μg/L compared to 21 μg/L when open). Benthic macrofaunal abundance and biomass are higher when the river mouth is closed: 16,700 individuals m−2 and 3.3 g m−2 compared to 8800 individuals m−2 and 2.4 g m−2 when the Rio Grande river mouth is open. Benthic macrofaunal community structure is divided into two groups: chironomid larvae and Oligochaeta dominated when the river mouth was closed, whereas polychaetes Mediomastus ambiseta and Streblospio benedicti dominated when the river mouth was open. The implications of these results for managing freshwater flows are that the open and closed conditions each have a characteristic benthic macrofaunal community that is strongly influenced by system hydrology.
A Developmental Approach for Training Deep Belief Networks
Authors: Zambra Matteo , Testolin Alberto , Zorzi Marco
Published: December 2022

Deep belief networks (DBNs) are stochastic neural networks that can extract rich internal representations of the environment from the sensory data. DBNs had a catalytic effect in triggering the deep learning revolution, demonstrating for the very first time the feasibility of unsupervised learning in networks with many layers of hidden neurons. These hierarchical architectures incorporate plausible biological and cognitive properties, making them particularly appealing as computational models of human perception and cognition. However, learning in DBNs is usually carried out in a greedy, layer-wise fashion, which does not allow to simulate the holistic maturation of cortical circuits and prevents from modeling cognitive development. Here we presentiDBN, an iterative learning algorithm for DBNs that allows to jointly update the connection weights across all layers of the model. We evaluate the proposed iterative algorithm on two different sets of visual stimuli, measuring the generative capabilities of the learned model and its potential to support supervised downstream tasks. We also track network development in terms of graph theoretical properties and investigate the potential extension ofiDBNto continual learning scenarios. DBNs trained using our iterative approach achieve a final performance comparable to that of the greedy counterparts, at the same time allowing to accurately analyze the gradual development of internal representations in the deep network and the progressive improvement in task performance. Our work paves the way to the use ofiDBNfor modeling neurocognitive development.
Alignment of design rules for additive manufacturing and remanufacturing
Authors: Schlesinger Linda , Koller Jan , Pagels Michelle , Döpper Frank
Published: December 2022

Remanufacturing is one key element of a circular economy by closing the loop on the product level and thus maintaining or restoring the product design and the associated product properties. The remanufacturing process chain involves disassembly of used products, cleaning of parts, inspection and sorting of parts, reconditioning or replenishment by new parts, and product reassembly into as-new products. If new parts are required, additive manufacturing is a promising alternative to conventional manufacturing or the purchase of spare parts. Additive manufacturing is characterized by the layered or element-based construction of parts and does not require product-specific tools, enabling a cost-efficient production of individual pieces or small series. The use of specific design rules in product and process development to meet the requirements of the intended process enables and simplifies additive manufacturing or remanufacturing. Despite the design rules for additive manufacturing and remanufacturing, there are no design rules for implementing additive manufacturing technology in the remanufacturing process. In this paper, existing design rules on Design for Additive Manufacturing and Design for Remanufacturing will first be identified and compared, and possible synergies and conflicts of objectives will be analyzed. Based on this, a guideline for a Design for Additive Remanufacturing is developed to facilitate and promote the implementation of additive manufacturing in remanufacturing. The developed design rules enable the evaluation of a part aimed to be produced by additive manufacturing within the remanufacturing process and give advice on how to optimize the design of the part. This paper aims to derive general design rules for a “Design for Additive Remanufacturing” that specifically address the additive remanufacturing process.
Fingerprint-inspired surface texture for the enhanced tip pinch performance of a soft robotic hand in lubricated conditions
Authors: Hao Tianze , Xiao Huaping , Liu Shuhai , Liu Yibo
Published: December 2022

The core capabilities of soft grippers/soft robotic hands are grasping and manipulation. At present, most related research often improves the grasping and manipulation performance by structural design. When soft grippers rely on compressive force and friction to achieve grasping, the influence of the surface microstructure is also significant. Three types of fingerprint-inspired textures with relatively regular patterns were prepared on a silicone rubber surface via mold casting by imitating the three basic shapes of fingerprint patterns (i.e., whorls, loops, and arches). Tribological experiments and tip pinch tests were performed using fingerprint-like silicone rubber films rubbing against glass in dry and lubricated conditions to examine their performance. In addition to the textured surface, a smooth silicone rubber surface was used as a control. The results indicated that the coefficient of friction (COF) of the smooth surface was much higher than that of films with fingerprint-like textures in dry and water-lubricated conditions. The surface with fingerprint-inspired textures achieved a higher COF in oil-lubricated conditions. Adding the fingerprint-like films to the soft robotic fingers improved the tip pinch gripping performance of the soft robotic hand in lubricated conditions. This study demonstrated that the surface texture design provided an effective method for regulating the grasping capability of humanoid robotic hands.
Improving the resilience of maritime supply chains: The integration of ports and inland transporters in duopoly markets
Authors: Shi Jia , Chen Jihong , Xu Lang , Di Zhongjie , Qu Qunzhen
Published: December 2022

The adverse impact of the outbreak of COVID-19 has reduced ports’ operational efficiency. In addition, ports and inland logistics providers are generally independent of each other and difficult to work together, which leads to time loss. Thus, as the core player, ports can integrate with inland logistics providers to improve the efficiency and resilience of maritime supply chains. This study examines the strategic options of two competing maritime supply chains consisting of ports and inland logistics providers. We investigate the impact of cooperation between ports and inland logistics providers and government regulation on the maritime supply chain by comparing members’ optimal pricing and overall social welfare under centralized, decentralized, and hybrid scenarios. Results indicate that the hybrid scenario is an equilibrium strategy for maritime supply chain, although this strategy is not optimal for governments seeking to improve supply chain resilience and maximize social welfare. Furthermore, observations show that through government economic intervention, both seaborne supplies can be incentivized to adopt an integrated strategy, and business and society can achieve a win–win situation.
CACA guidelines for holistic integrative management of glioma
Authors: Fan Daiming , Jiang Tao , Ma Wenbin , Jiang Chuanlu , You Yongping , Mao Ying , Qiu Xiaoguang , Kang Chunsheng , Li Gang , Mao Qing , Yang Xuejun , Qin Zhiyong , Liu Zhixiong , Wang Weimin , Wei Xinting , Li Wenbin , Liu Yunhui , Yu Rutong , Yu Xinguang , Kang Dezhi , Mou Yonggao , Wang Lei , Zhang Wei , Bao Zhaoshi , Chai Ruichao , Chen Baoshi , Fan Xing , Fang Shengyu , Li Guanzhang , Li Lianwang , Li Shouwei , Liu Xing , Liu Yanwei , Shan Xia , Wang Liang , Wang Yinyan , Wang Yu , Wang Zheng , Wang Zhiliang , Wu Chenxing , Yan Wei , Yang Pei , You Gan , Zhang Chuanbao , Zhang Zhong , Zhao Zheng
Published: December 2022

Glioma of the brain is a kind of tumor originating from neuroglial cells. It is the most common primary intracranial tumor, accounting for ~ 30% of all central nervous system tumors and 80% of malignant brain tumors. Glioma is characterized by high disability and recurrence rates. The disease seriously threatens the life of patients, affects their quality of life, and brings a heavy economic and psychological burden to patients, families, and society.

With the progression of molecular genetic testing technology and the completion of various clinical trials, the classification scheme for glioma is increasingly well established. Diagnosis and treatment regimens, including traditional and new regimens, are becoming increasingly specialized and standardized. The purpose is to develop a clinical diagnosis and treatment guideline for glioma in the Chinese population suitable for Chinese doctors and the general population based on domestic and international glioma research progress. Thus, domestic practitioners in the field can obtain current information and provide better service to patients with glioma, promoting the development of domestic clinical medicine and basic research on glioma.
Let the ruler be the ruler: aiming at truth in Xunzi’s doctrine of the rectification of names
Authors: Ryan Liam D.
Published: December 2022

How should we understand the Confucian doctrine of the rectification of names (zhengming): what does it mean that an object’s name must be in accordance with its reality, and why does it matter? The aim of this paper is to answer this question by advocating a novel interpretation of the later Confucian, Xunzi’s account of the doctrine. Xunzi claims that sage-kings ascribe names and values to objects by convention, and since they are sages, they know the truth. When we misuse names, we are departing from a sagely convention of naming. As sagely convention determines moral truth, departure from the linguistic convention of the sages is a departure from moral truth. On my interpretation of Xunzi, the rectification of names is not a doctrine about what is true, but a doctrine about how we aim at truth. We are aiming at descriptive truth when our language conforms to the correct name of an object according to what I call ‘Confucian conventionalism’. When we correctly aim at descriptive truth we can aim at moral truth. Therefore, I claim that the doctrine of the rectification of names is concerned with discerning the literal accordance of language with an object (what is descriptively, linguistically true), to determine what is normatively, or morally, true. According to Xunzi, moral truth is grounded in linguistic truth.
The Timing of Guilty Pleas
Authors: Cheng Kevin
Published: December 2022

While guilty pleas are the primary mode of criminal case dispositions across different legal jurisdictions, this topic remains an understudied area. The assumption is that defendants are 'playing the system' and that a sliding scale of sentence discounts is necessary to encourage early guilty pleas, which offer utilitarian benefits of efficiency. These assumptions lack a solid empirical foundation. This book offers a comprehensive investigation of how the timing of guilty pleas affects various facets of the criminal process, from the factors that affect this timing, to the effects that the sliding scale of sentence discounts have on sentences and public opinions about them. It also draws comparisons between Western and Asian legal systems, specifically those of England and Wales and Hong Kong. This book is addressed to scholars, legal practitioners, policymakers and those interested in criminal justice, socio-legal studies and empirical legal research.
Language in Culture
Authors: Silverstein Michael
Published: December 2022

Language enables us to represent our world, rendering salient the identities, groups, and categories that constitute social life. Michael Silverstein (1945–2020) was at the forefront of the study of language in culture, and this book unifies a lifetime of his conceptual innovations in a set of seminal lectures. Focusing not just on what people say but how we say it, Silverstein shows how discourse unfolds in interaction. At the same time, he reveals that discourse far exceeds discrete events, stabilizing and transforming societies, politics, and markets through chains of activity. Presenting his magisterial theoretical vision in engaging prose, Silverstein unpacks technical terms through myriad examples – from brilliant readings of Marcel Marceau's pantomime, the class-laced banter of graduate students, and the poetics/politics of wine-tasting, to Fijian gossip and US courtroom talk. He draws on forebears in linguistics and anthropology while offering his distinctive semiotic approach, redefining how we think about language and culture.
Property and its Forms in Classical German Philosophy
Authors: James David
Published: December 2022

The theme of property is directly relevant to some of the most divisive social and political issues today, such as wealth inequality and the question of whether governments should limit it by introducing measures that restrict the right to property. Yet what is property? And when seeking to answer this question, do we tend to identify the concept with just one dominant historical form of property? In this book, David James reconstructs the theories of property developed by four key figures in classical German philosophy - Kant, Fichte, Hegel and Marx. He argues that although their theories of property are different, the concept of social recognition plays a crucial role in all of them, and assesses these philosophers' arguments for the specific forms of property they claim should exist in a society that is genuinely committed to the idea of freedom.
Psychopathology
Authors: Carter Kenneth
Published: December 2022

Carter's Psychopathology is an accessible, engaging, and well-organized text covering the study, understanding, diagnosis, treatment, and prevention of psychological disorders. Fully integrating gender and culture in the presentation of mental disorders, and using a sensitive and inclusive language to encourage an empathic approach to psychopathology, this introductory textbook offers students a strong foundation of the socio-cultural factors influencing how we treat mental disorders. Featuring: boxes such as 'the power of words', promoting the use of respectful, empathic language, and 'the power of evidence', demonstrating that scientific evidence can answer questions about psychopathology treatments; real-world case studies and examples; 'concept checks' questions to test the student's mastery of the material covered in each section; chapter summaries listing the 'take-home' points discussed; and key terms and glossary highlighting terms that students will need to understand and become familiar with, this textbook provides a hands-on approach to the study of psychopathology.
Quantum Mechanics
Authors: Nastase Horatiu
Published: December 2022

Written for a two-semester graduate course in Quantum Mechanics, this comprehensive text helps develop the tools and formalism of Quantum Mechanics and its applications to physical systems. It suits students who have taken some introductory Quantum Mechanics and Modern Physics courses at undergraduate level, but it is self-contained and does not assume any specific background knowledge beyond appropriate fluency in mathematics. The text takes a modern logical approach rather than a historical one and it covers standard material, such as the hydrogen atom and the harmonic oscillator, the WKB approximations and Bohr-Sommerfeld quantization. Important modern topics and examples are also described, including Berry phase, quantum information, complexity and chaos, decoherence and thermalization, nonstandard statistics, as well as more advanced material such as path integrals, scattering theory, multiparticles and Fock space. Readers will gain a broad overview of Quantum Mechanics, as solid preparation for further study or research.
Mourir en mer en Méditerranée
Authors: Fusaro Maria
Published: December 2022

Cet article s’intéresse à la succession ab intestat au sein de la République de Venise comme un moyen d’analyser l’interaction entre la procédure juridique et l’économie politique. En se concentrant sur les personnes décédées ab intestat à bord de navires vénitiens et en replaçant les règles de ces successions dans le contexte de l’économie politique de la République, il défend l’importance des biens meubles en termes économiques et sociaux. Ce faisant, il examine la manière dont les règlements et les procédures concernant les successions intestats étaient conçus pour protéger les réseaux de crédit et les intérêts commerciaux, des négoces de riches marchands jusqu’aux transactions à petite échelle de marins et de gens de mer, en nous intéressant aussi à la manière dont cela affectait leurs épouses. L’essai soutient que Venise utilisait la réciprocité dans ces domaines comme un moyen de soutenir ses objectifs économiques. Enfin, il suggère comment cette source documentaire peut permettre à de futures recherches de réévaluer la richesse matérielle des marins dans la Méditerranée du xviie siècle et leurs activités de micro-entrepreneurs.
Lobbying the executive branch: Unpacking access to political heads, political advisers, and civil servants
Authors: Albareda Adrià , Saz-Carranza Angel , Van Acoleyen Michiel , Coen David
Published: December 2022

This article systematically examines how access of business groups and nongovernmental organizations (NGOs) to the executive branch of the European Union varies across political heads, civil servants, and an understudied yet critical intermediary figure of the executive branch: political advisers. Building upon exchange theory, we argue that the occurrence of a meeting between public officials and interest groups depends on information and legitimacy sought and offered by both types of actors, the public officials’ public exposure, and the interest groups’ lobbying strategies. The empirical analysis is focused on the executive body of the European Union (i.e., the European Commission). Our results show that, while political advisers and civil servants are more likely to meet with business groups than with NGOs, political heads are not biased in favor of any of these two groups.
Two Ways of Completing the European Fundamental Rights Union: Amendment to vs. Reinterpretation of Article 51 of the EU Charter of Fundamental Rights
Authors: JAKAB András , KIRCHMAIR Lando
Published: December 2022

The aim of this Article is to show that the enforcement of Article 2 of the Treaty on European Union (‘TEU’) values vis-à-vis Member States could benefit from the application of the EU Charter of Fundamental Rights (‘CFR’) also in instances where the current interpretation of Article 51(1) CFR prevents this. This would be the case if the CFR were also applicable to purely domestic cases, eg—but not only—with regard to fundamental rights-relevant violations related to the values enshrined in Article 2 TEU. In this case, the European Court of Justice, which has already partly taken this path recently, could prevent the violation of core EU values. The most important historical challenge to those values in Europe today is the systematic dismantling of the rule of law and democracy in certain Member States. It is the very purpose of fundamental rights to provide answers to such dangers. When one speaks of the rule of law and democracy, one necessarily also means fundamental rights. This Article thus advocates an EU which perceives itself as a complete fundamental rights union. While the traditional interpretation of Article 51(1) CFR had a balanced division of competence between the EU and its Member States in mind, the disregard of Article 2 TEU values triggers a clausula rebus sic stantibus: the neat federal balance can only be upheld if both ends stick to the original promise made. It demonstrates two ways of completing the European fundamental rights union: treaty revision, on the one hand, and reinterpretation of Article 51 CFR, on the other hand. Both ways have in common that only a complete fundamental rights union can establish a system of fundamental rights protection that is uniform and thus equality-preserving in cases where national fundamental rights fail to provide sufficient protection.
Maternal health intervention and sex ratios: evidence from the Village Midwife Program in Indonesia
Authors: Ahsan Md Nazmul , Maharaj Tattwachaitanya Riddhi
Published: December 2022

In about last three decades, many developing countries have experienced a large decline in maternal mortality rates. Global initiatives leading to better maternal health policies may have contributed to this decline. In this paper, we investigate whether maternal health intervention also improves the fetal survival rate. For this purpose, we consider the Village Midwife Program in Indonesia, which was launched in 1989 as a part of the safe motherhood strategy. Using the Indonesian Family Life Survey (IFLS), we investigate the impact of midwives on fetal survival rate in terms of a change in the likelihood of a live birth being male. Our results show that the provision of a midwife in a community increases the probability of a live birth being male by about 3 percentage points. Greater antenatal care, skilled birth-attendance, and an improvement in nutrition among reproductive-age women—in terms of greater BMI—are the likely pathways. We do not find the results to be driven by pre-treatment trends, and they remain robust to a number of checks.
The Myth of the Good Epistemic Bubble
Authors: Sheeks Meredith
Published: December 2022

Intellectual interest in epistemic bubbles and echo chambers has grown exponentially over the past two decades. This is largely because many assume, in light of recent events, that these phenomena are morally, socially, politically, and epistemically problematic. But are we justified in simply assuming that epistemic bubbles and echo chambers are inherently epistemically problematic? Perhaps surprisingly, numerous philosophers have recently argued that epistemic bubbles and echo chambers are not intrinsically epistemically problematic. Nevertheless, I argue, this trend is mistaken. Epistemic bubbles and echo chambers are all intrinsically epistemically problematic, such that we should try to escape them, if we find ourselves in them. Crucially, there are two senses in which we might identify epistemic bubbles and echo chambers as being intrinsically epistemically problematic, as opposed to “good.” After distinguishing between these senses, I demonstrate that, even if there is a sense in which epistemic bubbles can in principle be “good,” all epistemic bubbles are epistemically problematic in the sense that is ultimately relevant to the question of whether we ought to stay in epistemic bubbles or to try to get out of them.