bluuebunny/crossref_metadata_2025 huggingface dataset:
THE ALZHEIMER’S PREVENTION CLINIC AT WEILL CORNELL MEDICAL COLLEGE / NEW YORK - PRESBYTERIAN HOSPITAL: RISK STRATIFICATION AND PERSONALIZED EARLY INTERVENTION
Authors: Seifan A. , Isaacson R.
Published: November 2021

In July 2013, Weill Cornell Medical College founded the first Alzheimer’s Prevention Clinic (APC) in the United States, providing direct clinical care to family members of patients with Alzheimer’s disease (AD) as part of the Weill Cornell Memory Disorders Program. At the APC, patients seeking to lower their AD risk undergo a comprehensive assessment, receive a personalized plan based on rapidly evolving scientific evidence, and are followed over time using validated as well as emerging clinical and research technologies. The APC approach applies the principles of pharmacogenomics, nutrigenomics and clinical precision medicine, to tailor individualized therapies for patients. Longitudinal measures currently assessed in the clinic include anthropometrics, cognition, blood biomarkers (i.e., lipid, inflammatory, metabolic, nutritional) and genetics, as well as validated, self-reported measures that enable patients to track several aspects of health-related quality of life. Patients are educated on the fundamental concepts of AD prevention via an interactive online course hosted on Alzheimer’s Universe (www.AlzU.org), which also contains several activities including validated computer-based cognitive testing. The primary goal of the APC is to employ preventative measures that lower modifiable AD risk, possibly leading to a delay in onset of future symptoms. Our secondary goal is to establish a cohort of at-risk individuals who will be primed to participate in future AD prevention trials as disease-modifying agents emerge for testing at earlier stages of the AD process. The clinical services are intended to lower concern for future disease by giving patients a greater sense of control over their brain health.
RELAÇÃO ENTRE FAMÍLIA E ESCOLA NA COMUNIDADE DO POVO NOVO (RIO GRANDE/RS) PELA PERSPECTIVA DO DESENVOLVIMENTO BIOECOLÓGICO
Authors: Valle Hardalla Santos do , Coronel Adriana
Published: November 2021

O presente trabalho tem como objetivo discutir a relação entre família e escola na comunidade do 3º Distrito do Povo Novo (Rio Grande/RS). Uma zona rural, que possui em torno de oito mil habitantes e constitui a sua base econômica a partir de atividades relacionadas à pecuária, à agricultura e aos pequenos comércios. Para compreender a relação entre família e escola, foram realizadas entrevistas semiestruturadas com educadores e familiares de crianças do 3º ano do ensino fundamental, pertencentes a 3 escolas públicas da localidade. O aporte teórico utilizado foi a bioecologia do desenvolvimento humano, elaborada por Bronfenbrenner (2011). Essa postula o fato de que, durante o processo de desenvolvimento humano, diferentes circunstâncias sociais podem afetar as características subjetivas de um indivíduo. Conclui-se nesse artigo, que a teoria bioecológica pode contribuir para a compreensão da relação entre família e escola, agregando também ao processo de ensino e aprendizagem das crianças.
PRODUÇÃO CIENTÍFICA SOBRE EDUCAÇÃO FÍSICA NA EDUCAÇÃO INFANTIL A PARTIR DOS PERIÓDICOS BRASILEIROS DA ÁREA
Authors: Pinheiro Gabriela Souza , Souza Vânia de Fátima Matias de , Flores Patric Paludett
Published: November 2021

O presente estudo objetivou levantar a produção científica dos periódicos nacionais da área de Educação Física, no período de 2008-2018, sobre a Educação Física na Educação Infantil. Destaca-se que esta pesquisa é do tipo revisão integrativa, na qual foram analisados artigos científicos publicados em 14 revistas nacionais, classificadas com Qualis B2 ou superior, que contemplam em seu escopo a área da Educação Física. Foram encontrados 668 artigos que passaram por critérios de inclusão e exclusão, sendo selecionados no final 34 artigos. Após a seleção dos artigos, a análise constituiu-se a partir dos indicativos da análise por temáticas, possibilitando a criação de três sessões de análise: a) mapeamento dos autores das produções sobre Educação Física na Educação Infantil; b) procedimentos metodológicos abordados nas produções sobre Educação Física na Educação Infantil; e c) principais temáticas abordadas nas pesquisas selecionadas a respeito da Educação Física na Educação Infantil. A partir dos resultados, identificou-se que o Sudeste é a região com mais pesquisadores que abordam a temática; a maioria das pesquisas adotou os pressupostos da pesquisa qualitativa para desenvolver seus estudos; e, em relação às temáticas, foram evidenciadas cinco categorias principais, sendo elas: Possibilidades Pedagógicas, Formação Profissional, Inclusão Escolar, Documentos Norteadores e Manifestações Corporais. De modo geral, as temáticas refletiram a importância de se ter um profissional de Educação Física inserido na Educação Infantil, a fim de potencializar o desenvolvimento das crianças nessa etapa do ensino, a partir de um contexto teórico e prático da disciplina para o desenvolvimento e condução dos conhecimentos que emergem da área.
“EU TÔ TENTANDO SOBREVIVER NO INFERNO”
Authors: Oliveira Wenderson Silva , Farias Isabel Maria Sabino de
Published: November 2021

Desde março do ano de 2020 o Brasil vive a pandemia do novo coronavírus (Sars-CoV-2), e se transformou em um dos países que mais sofrem com uma política que precariza as vidas da população, sobretudo de pessoas com deficiência, pobres, LGBT, negras/os, indígenas e outras tantas que são sumariamente ignoradas pela necropolítica, que dita quem pode viver e quem deve morrer. O ensino de música na Educação Básica no Brasil, na Base Nacional Comum Curricular (BNCC), desconsidera a diversidade étnico-racial, de gênero, sexual, corporal e de classe, e com isso provoca um aniquilamento de saberes múltiplos que decorrem das mais diversas práticas musicais presentes no país. Ao levar em conta esse cenário de exclusão promovido pela BNCC e as violências às minorias sociais, este artigo objetiva problematizar currículos em educação musical e as precariedades provocadas pelo estado pandêmico. Pretendemos, a partir das vivências de uma de nós como professora de música no município de Sobral/CE, discutir como temos produzido currículos que, em aliança, resistem e enfrentam as formas precárias as quais nossos corpos são submetidos, currículos que proporcionam possibilidades das múltiplas corporeidades existirem, como nos mostra Felipe, aluno transexual masculino do nono ano do ensino fundamental. Lançamos essas palavras para pensar possibilidades curriculares a partir de nossa luta por uma educação musical justa, inclusiva e democrática.
EDUCAÇÃO EM GÊNERO E SEXUALIDADE
Authors: Chaves Jacqueline Cavalcanti , Kertzman Nina Queiroz
Published: November 2021

A educação em gênero e sexualidade na escola é questão controversa que se desenrola em um campo de disputa que tem se acirrado nos últimos anos. A problemática apresenta uma série de dilemas, tal como o modelo de formação de profissionais. O objetivo deste trabalho é examinar a formação inicial e continuada de professoras e professores a partir da revisão da literatura; da apresentação de um projeto de extensão caracterizado como formação continuada em gênero e sexualidade; e, através do método de interpretação de sentidos, da análise dos relatórios elaborados durante o projeto. A análise desenvolvida aponta para a necessidade de propiciar uma formação que não seja apenas instrumental, centrada em conceitos e informações; rompa com tradicionais cisões entre objetividade e subjetividade, razão e emoção; crie espaços de fala e escuta qualificada; promova reflexão crítica a respeito dos saberes, práticas e capacidade de agência das/dos participantes; inclua outras/outros profissionais da escola, além de docentes; discuta temas distintos aos tradicionalmente elencados; e utilize outras metodologias, materiais e linguagens que favoreçam a afetação, o engajamento e o rompimento do já instituído, de padrões automatizados, caracterizados por preconceitos, estereótipos e discriminações.
UNIVERSIDADESCOLA E AS DISPUTAS NO CONTEXTO DA PANDEMIA
Authors: Freitas Filho Luciano Carlos Mendes , Sussekind Maria Luiza
Published: November 2021

O presente texto se insurge a partir do olhar teórico decolonial na perspectiva de problematizar os enunciados reformistas de controle e responsabilização, estimulados por setores empresariais e governamentais conservadores que, atualmente, têm investido na legitimação de políticas de ensino e pesquisa de simplificação e unilateralidade dos currículos e práticas docentes nas escolas e nas universidades brasileiras. Escrito sob a égide do imprevisível e do emergencial que a pandemia de Covid-19 tem provocado, buscamos, em contrapartida, a partir de uma análise de discursos concernentes a um contexto de ensino e pesquisa universitários, fazer uso desses mesmos sentidos de incerteza e urgência pandêmicas para trazer uma defesa dos sentidos plurais das universidadescolas. Para tanto, localizamos movimentos pós-abissais, na perspectiva de produzir giros e deslocamentos epistêmicos no que diz respeito ao pensar ensino e pesquisa por meio de um currículo e de uma docência desviantes, em que os conhecimentos e vivências ausentes ou distanciados por modos de pensamentos coloniais se instituam nesse cenário pandêmico (e no porvir pós-pandêmico), em movimentos de resistência e criação por uma copresença no campo epistemológico e em defesa dos currículos como territórios plurais de aprenderensinar das universidadescolas como aparelhos públicos e do público.
PROTAGONISMO DOCENTE NA EDUCAÇÃO DAS RELAÇÕES ÉTNICO-RACIAIS
Authors: Marques Eugenia Portela de Siqueira , Conte Patrícia Portela de Siqueira , Silva Wilker Solidade da
Published: November 2021

O artigo sustenta que as Diretrizes Curriculares Nacionais para a Educação das Relações Étnico-Raciais (DCNERER) provocou um deslocamento epistêmico do currículo e das práticas pedagógicas ao questionar os saberes eurocêntricos que historicamente foram legitimados de maneira generalizante e universal e que silenciaram os saberes africanos e afro-brasileiros no território brasileiro. O estudo foi realizado pelos pesquisadores do Grupo de Pesquisa sobre relações raciais e formação de professores e se configura como pesquisa de natureza qualitativa, com abordagem teórica, inspirada nos estudos pós-coloniais. O campo observado foram as escolas públicas municipais de Campo Grande-MS. A hipótese a ser averiguada é o protagonismo do professor para garantir a efetivação das DCNERER e os conteúdos propostos sobre a valorização da cultura africana e afro-brasileira na educação básica no contexto da pandemia. Compreende-se que, com o aligeiramento na reorganização curricular e aulas remotas, manter as DCNERER é uma maneira de expressar uma resistência epistemológica em prol da defesa da escola democrática.
Covid-19! QUEM 'DESCOBRIU' QUEM?
Authors: Paraskeva Joao Menelau
Published: November 2021

Vivemos em uma era que normalizou o absurdo e a anormalidade. De sucessivos caoses econômicos e ambientais devastadores, o mundo está agora diante de uma pandemia com uma pegada letal em todo o planeta. O pandemônio se tornou global. Este artigo situa a atual pandemia de Covid-19 no contexto de uma infinita pletora de sagas devastadoras, empurrando a humanidade para uma regressão inimaginável. Ao fazer isso, o artigo examina como essa pandemia reflete as próprias cores de uma cegueira epistemológica intencional, que enquadra o raciocínio eurocêntrico, paralisou a economia política do capitalismo global aprofundando e acelerando uma crise sem fim e sem parar, que começou em 2008. O artigo também explora a construção social da pandemia atual e defende formas de pensar e fazer educação e teoria do currículo, alternativamente, para desafiar o raciocínio eurocêntrico ocidental moderno. Ao fazer isso, avança a teoria itinerante do currículo como uma abordagem justa, uma “teoria do agora“ apenas alter-currículo, que respeita a diversidade pluri-epistemológica do mundo e visa se deslocar de utopias enquadradas dentro das fronteiras determinadas pela colonialidade em direção a um clímax anticolonial e “heretópico”.
PERSPECTIVAS PEDAGÓGICAS EM INICIAÇÃO CIENTÍFICA
Authors: Oliveira Dr. Victor Hugo Nedel , Vasques Daniel Giordani
Published: November 2021

Os processos pedagógicos da Iniciação Científica na escola básica favorecem o crescimento do senso crítico e do entendimento sobre o universo científico. O objetivo desse texto foi analisar os documentos do Colégio de Aplicação da UFRGS em relação às propostas pedagógicas para com o componente curricular de Iniciação Científica. Metodologicamente, tratou-se de pesquisa qualitativa que realizou levantamento e análise documental. O regimento da instituição apresenta expressões relacionadas à ciência referentes às instâncias administrativas da escola e o Projeto Político Pedagógico não foi disponibilizado pela direção da instituição. Por sua vez, os projetos de equipe e os programas de estudos apontam a pesquisa científica na escola enquanto processo, bem como apresentam particularidades em cada etapa escolar. É possível considerar que, apesar de certas lacunas, destaca-se a importância dada ao componente na grade curricular e aos esforços na construção dos materiais pedagógicos.
Kajian Status Mutu Air dan Identifikasi Sumber Pencemaran Sungai Cidurian Segmen Hilir Menggunakan Metode Indeks Pencemaran (IP)
Authors: Novianti Novianti , Zaman Badrus , Sarminingsih Anik
Published: November 2021

Sungai Cidurian adalah salah satu sungai yang mengalir di Kabupaten Tangerang dan Kabupaten Serang yang melintasi 17 (tujuh belas) kecamatan dan 2 (dua) kabupaten dengan panjang 67,5 Km. Kajian dilakukan untuk menganalisis status kualitas air Sungai Cidurian pada segmen hilir agar dapat mengetahui kondisi dan tingkat status mutu airnya sehingga dapat mengambil kebijakan pengelolaan dan pengendalian pencemaran dengan tepat. Penelitian dilakukan pada saat musim kemarau dan musim hujan. Nilai status mutu air dianalisis dengan Metode Indeks Pencemaran (IP) yang perhitungannya mengacu pada KepMen LH No. 115 Tahun 2003 tentang Pedoman Penentuan Status Mutu Air.  Hasilnya menunjukan pada 4 (empat) lokasi titik sampling memperlihatkan rata-rata nilai Indeks Pencemaran (IP) pada hilir sungai dalam kondisi baik dan cemar ringan berdasarkan Baku Mutu Kelas II PP 22/2021, untuk nilai Indeks Pencemaran (IP) terendah sebesar 0,66 dan tertinggi sebesar 1,56. ABSTRACTThe Cidurian River is one of the rivers that flows in Tangerang Regency and Serang Regency which crosses 17 (seventeen) sub-districts and 2 (two) districts with a length of 67.5 Km. The study was carried out to analyze the water quality status of the Cidurian River in the downstream segment in order to know the condition and level of the water quality status so that it could take appropriate pollution management and control policies. The research was conducted during the dry season and the rainy season. The value of water quality status was analyzed by using the Pollution Index Method (IP), the calculation refers to the Minister of Environment Decree No. 115 of 2003 concerning Guidelines for Determining Water Quality Status. The results show that at 4 (four) sampling point locations, the average Pollution Index (IP) value in the downstream river is in good condition and lightly polluted based on the Class II PP 22/2021 Quality Standard, for the lowest Pollution Index (IP) value of 0, 66 and the highest of 1.56.
Finding Ways to Attract Clients: A Content Analysis of Japanese Language Tutors’ Ads in an Online Tutor Marketplace
Authors: Patria Aditya Nur
Published: November 2021

The growing number of freelance marketplaces allows students to earn extra money as tutors. The hyper-competitive nature in the marketplaces forces students to compete with non-student tutors in order to get clients (Popiel, 2017). Non-student tutors may be better equipped with a lot of experiences. However, all freelance tutors need to post impressive ads to get their clients, particularly in a niche subject such as Japanese language. The present study explores the differences of information put in ads between student tutors and non-student tutors on a tutor marketplace, Superprof. Content analysis (Cohen et al, 2011) was used to identify categories of information in the ads. The results show that there were 11 categories of information including tutors’ name, origin, current employment status, education background, language proficiency certificate, course level, course type, rhetoric, experience in Japan, coverage area, and availability. The data were then analyzed statistically to find the categories of information with a significant difference. It shows that both groups have difference in putting information related to their current employment status (t = 3.88, p < 0.001, d = 1.05) and their education background (t = 2.78, p < 0.005, d = 0.75). The implication of the study is that student tutors tend to value their relationship with academic institutions and make it as a bargaining power to market their skills in the marketplace.
Japanese and Indonesian Relative Clausa Patterns
Authors: Pradhana Ngurah Indra
Published: November 2021

In this research, the object of study is clause. This research is focused on the derivation of clauses known as relative clauses. In this study, it was examined about the differences and similarities in the formation patterns, meanings, and relation characteristics of clauses which are relatively good in two languages, namely between Japanese and Indonesian. The results of this research can be used in the teaching and learning process. As well as useful for readers and audiences who intend to pursue linguistics. The analytical method used in this research is the agih method. Based on the analysis that has been done, several conclusions can be drawn as follows. In Indonesian, a relative clause is indicated by the word "yang" as a conjunctive pronoun. Relative clauses can be used as an expansion technique. There is a slight difference in the formation of Relative Clauses in Indonesian and Japanese, namely, in Indonesian the relative clause can only consist of the word "yang" as a relative clause marker and a predicate which functions as a modifier which is then followed by a core sentence. Whereas in Japanese, a relative clause consists of a minimum of objects and a predicate as a modifier followed by a core sentence. Semantically, relative clauses are viewed from proportions formed by a predicate which states activities, processes, or circumstances. The characteristic of the relation in a relative clause is indicated by the word that comes after the noun.
Pembentukan Dajare Pada Drama 99.9 ~Keiji Senmon Bengoshi~ Season Dua Episode Dua
Authors: Salisah Talin , Suryadimulya Agus Suherman , Sunarni Nani
Published: November 2021

Japanese has a wordplay similar to the English wordplay, puns. The wordplay term is dajare. Dajare is a wordplay that relies on identical words, where the meanings are different. This article focuses on the formation of dajare sentences in the drama 99.9 ~Keiji Senmon Bengoshi~ season two episode two from nine episodes. The analysis process was using qualitative methods. The results of the analysis of the dajare sentences found in the drama show that particles can also help in the formation of dajare. In addition, the speaker or dajare the speakers will look for the exact word that he wants to say. In view of the response of humor itself, depending on the atmosphere and feelings received by the listener.
Adopting Work-style Reforms, Promoting the Inclusive Workplace: Japan’s Strategies on the Diversifying Labor Market
Authors: Budianto Firman
Published: November 2021

As a response to the diversifying labor market, the government of Japan has released a set of policies to foster productivity and increase participation of not only women but also seniors, people with disabilities, and foreigners in the country’s job market. However, the literature on the diversification of Japan’s labor force has paid little attention to the Japanese government’s perspectives on this issue. This qualitative study, therefore, examines the current Japanese government’s strategies in regards with the changing domestic labor market and workplace through critical analyses of the government’s policies and publications. This study observed that the government of Japan has set out to adopt work-style reforms and promote an inclusive workplace for everyone. These two key policies should address the inequality and the work-life balance issues as the core obstacle in Japan’s business practices. This present study suggests that fundamental reforms in the way Japanese people work might pave the way to solving the country’s economic and sociocultural challenges that, to some extent, are rooted in the structural problems in the workplace.
On well-posedness of semilinear Rayleigh-Stokes problem with fractional derivative on ℝ
N
Authors: He Jia Wei , Zhou Yong , Peng Li , Ahmad Bashir
Published: November 2021

We are devoted to the study of a semilinear time fractional Rayleigh-Stokes problem on ℝ
N
, which is derived from a non-Newtonain fluid for a generalized second grade fluid with Riemann-Liouville fractional derivative. We show that a solution operator involving the Laplacian operator is very effective to discuss the proposed problem. In this paper, we are concerned with the global/local well-posedness of the problem, the approaches rely on the Gagliardo-Nirenberg inequalities, operator theory, standard fixed point technique and harmonic analysis methods. We also present several results on the continuation, a blow-up alternative with a blow-up rate and the integrability in Lebesgue spaces.
Probing biomechanical properties of the cornea with air-puff-based techniques – an overview
Authors: Mlyniuk Patryk , Maczynska-Walkowiak Ewa , Rzeszewska-Zamiara Jagoda , Grulkowski Ireneusz , Kaluzny Bartlomiej J.
Published: November 2021

The cornea is a part of the anterior segment of the eye that plays an essential optical role in refracting the light rays on the retina. Cornea also preserves the shape of an eyeball and constitutes a mechanical barrier, protecting the eye against the factors of the external environment. The structure of the cornea influences its biomechanical properties and ensures appropriate mechanical load transfer (that depends on the external environment and the intraocular pressure) while maintaining its shape (to a certain extent) and its transparency. The assessment of the corneal biomechanics is important in clinical ophthalmology, e.g. in the diagnosis of ectatic corneal diseases, for precise planning of the refractive surgery, and in accurate determination of the intraocular pressure. A standard technique to determine corneal biomechanics requires the application of well-defined mechanical stimulus (e.g. air puff) and performing simultaneous imaging of the response of the tissue to the stimulus. A number of methods to assess the biomechanical properties of the cornea have been developed, including ultrasound, magnetic resonance imaging, and optical methods as visualization modalities. Commercially available methods include the ocular response analyzer (ORA) and corneal visualization scheimpflug technology (Corvis ST). Currently advanced research is conducted using optical coherence tomography (OCT). The extension of OCT called optical coherence elastography (OCE) possesses high clinical potential due to the imaging speed, noncontact character, and high resolution of images.
Estimating the potential of wind energy resources using Weibull parameters: A case study of the coastline region of Dar es Salaam, Tanzania
Authors: Michael Enock , Tjahjana Dominicus Danardono Dwi Prija , Prabowo Aditya Rio
Published: November 2021

This study aimed to compare the graphical method (GM) and standard deviation method (SDM), based on analyses and efficient Weibull parameters by estimating future wind energy potential in the coastline region of Dar es Salaam, Tanzania. Hence, the conclusion from the numerical method comparisons will also determine suitable wind turbines that are cost-effective for the study location. The wind speed data for this study were collected by the Tanzania Meteorological Authority Dar es Salaam station over the period of 2017 to 2019. The two numerical methods introduced in this study were both found to be appropriate for Weibull distribution parameter estimation in the study area. However, the SDM gave a higher value of the Weibull parameter estimation than the GM. Furthermore, the five selected commercial wind turbine models that were simulated in terms of performance were based on a capacity factor using the SDM and were both over 25% the recommended capacity factor value. The Polaris P50-500 commercial wind turbine is recommend as a suitable wind turbine to be installed in the study area due to its maximum annual capacity factor value over 3 years.
Analysis of the aging mechanism and life evaluation of elastomers in simulated proton exchange membrane fuel cell environments
Authors: Li Guo , Zhu Dasheng , Jia Wenhua , Zhang Feng
Published: November 2021

This paper studies the aging mechanism of elastomeric gaskets made from silicone rubbers in simulated proton exchange membrane fuel cells (PEMFCs) in humid, acidic, and high-temperature environments. The changes in the surface morphology are observed using optical microscopy. Attenuated total reflection Fourier transform infrared spectroscopy (AFT-FTIR) and X-ray photoelectron spectroscopy (XPS) are used to investigate the changes in the chemical molecular structure. The stress relaxation test is conducted to characterize the decay process of the mechanical properties. The results indicate that cracks appear on the surface and that the aging mechanism is mainly due to decomposition in the backbone and hydrolysis of the crosslinking. The stress relaxation modulus decreases as the acid concentration increases, which suggests a decrease in elasticity and an increase in brittleness. A master curve that relates time and concentration is constructed. Based on this inference, the experimental time can be shortened by about four times.
Modular network inference between miRNA–mRNA expression profiles using weighted co-expression network analysis
Authors: Wani Nisar , Barh Debmalya , Raza Khalid
Published: November 2021

Connecting transcriptional and post-transcriptional regulatory networks solves an important puzzle in the elucidation of gene regulatory mechanisms. To decipher the complexity of these connections, we build co-expression network modules for mRNA as well as miRNA expression profiles of breast cancer data. We construct gene and miRNA co-expression modules using the weighted gene co-expression network analysis (WGCNA) method and establish the significance of these modules (Genes/miRNAs) for cancer phenotype. This work also infers an interaction network between the genes of the turquoise module from mRNA expression data and hubs of the turquoise module from miRNA expression data. A pathway enrichment analysis using a miRsystem web tool for miRNA hubs and some of their targets, reveal their enrichment in several important pathways associated with the progression of cancer.
Advances in the therapeutic approach of pudendal neuralgia: a systematic review
Authors: Murer Sébastien , Polidori Guillaume , Beaumont Fabien , Bogard Fabien , Polidori Élisa , Kinne Marion
Published: November 2021

Context

Although pudendal neuralgia (PN) has received growing interest over the last few years, diagnosis remains difficult, and many different therapeutic approaches can be considered.

Objectives

This article aims to provide an overview of the possible treatments of PN and investigate their efficacies.

Methods

Utilizing PubMed and ScienceDirect databases, a systematic review was carried out and allowed identification of studies involving patients with PN, as defined by Nantes criteria, and their associated treatments. Relevant data were manually reported.

Results

Twenty-eight articles were selected, totaling 1,013 patients (mean age, 49 years) and six different types of interventions. Clinical outcomes, most frequently quantified utilizing the Visual Analog Scale (VAS), vary greatly with both the therapy and time after intervention (from 100 to <10%). However, neither peri nor postoperative serious complications (grade > II of Clavien–Dindo classification) are reported. Although surgery seems to provide a higher proportion of long-term benefits, identifying the most efficient therapeutic approach is made impossible by the multitude of outcome measurements and follow-up frequencies. It should also be noted that literature is sparse regarding randomized controlled trials with long-term follow-up.

Conclusions

Although there are a number of modalities utilized for the treatment of PN, there are no current recommendations based on treatment efficacies. This seems to be largely in part caused by the lack of standardization in outcome quantification. Future research in this field should focus on prospective cohort studies with high levels of evidence, aimed at assessing the long-term, if not permanent, benefits of available therapies.
Distribution update, male genitalia, natural history, and conservation of the stump-tailed porcupine Coendou rufescens in South America
Authors: Ramírez-Chaves Héctor E. , Torres-Martínez María M. , Henao-Osorio Jose J. , Osbahr Karin , Concha-Osbahr Catalina , Passos Fernando C. , Noguera-Urbano Elkin
Published: November 2021

The stump-tailed porcupine, Coendou rufescens, is a widely distributed but scarcely documented species inhabiting the Andean region of Colombia, Ecuador, Peru, and an isolated population in Bolivia. Despite the wide distribution different aspects on its biology and ecology are still unknown. We present an update to the distribution of C. rufescens, and recent observations on the anatomy, natural history, and conservation in Colombia. For this, we described the male genitalia and present data on reproductive periods, plants used and consumed, and threats. The distribution of C. rufescens comprises 12 ecoregions in an area of 376,225 km2 for the northern group (Colombia, Ecuador, and Peru) and 393 km2 for the southern group (Bolivia). The highest elevational record is in Ecuador (4387 m), being the porcupine inhabiting at highest elevations. The anatomy of the glans is similar to that observed in Coendou quichua and constitutes the second species of Coendou with available information on glans morphology. C. rufescens consumes fruits and leaves of potato cider (Sechium edule: Cucurbitaceae) and woody shrub (Bejaria: Ericacea), and usually perches even in exotic species such as pines. Finally, common treats for the species in Colombia are related to hunting pressures, predation by domestic dogs, and roadkills.
Crystal structure of 4,5-diiodo-1,3-dimesityl-1H-1,2,3-triazol-3-ium chloride – chloroform (1/1), C21H23Cl4I2N3
Authors: Xu Xingyu , Qiu Ping
Published: November 2021

C21H23Cl4I2N3, monoclinic, P21/c (no. 14), a = 26.110(2) Å, b = 9.1149(8) Å, c = 33.793(3) Å, β = 134.138(3)°, V = 5771.8(9) Å3, Z = 8, R

gt
(F) = 0.0624, wRref
(F
2) = 0.1525, T = 297.93 K.
Spanish usted as an imposter
Authors: Collins Chris , Ordóñez Francisco
Published: November 2021

Across dialects, Spanish uses the third person forms usted and ustedes to refer to the addressee. In this squib, we propose an imposter analysis of these forms in the framework of Collins and Postal (2012. Imposters. MIT Press, Cambridge.).
Deep learning for tilted-wave interferometry
Authors: Hoffmann Lara , Fortmeier Ines , Elster Clemens
Published: November 2021

The tilted-wave interferometer is an interferometrical measurement system for the accurate optical form measurement of optical aspheres and freeform surfaces. Its evaluation procedure comprises a high-dimensional inverse problem to reconstruct the form of the surface under test from measured data. Recent work has used a deep learning hybrid approach to solve the inverse problem successfully in a simulation environment. A quantification of the model uncertainty was incorporated using ensemble techniques. In this paper, we expand the application of the deep learning approach from simulations to measured data and show that it produces results similar to those of a state-of-the-art method in a real-world environment.
Resultatives and low depictives in English
Authors: Ausensi Josep , Bigolin Alessandro
Published: November 2021

We argue against a purely semantic account of the Unique Path Constraint (Goldberg, Adele. 1991. It can’t go down the chimney up: Paths and the English resultative. InProceedings of the seventeenth annual meeting of theBerkeley Linguistics Society, 368–378.), i.e., the constraint that there can only be one result state in a single clause, and in favor of a syntactic restriction regarding event structure. We propose, following Mateu, Jaume & Víctor Acedo-Matellán. 2012. The manner/result complementarity revisited: A syntactic approach. In M. Cristina Cuervo & Yves Roberge (eds.),The end of argument structure? Syntax and semantics, 209–228. New York: Academic Press, that structurally there can only be one result predicate per clause since the littlevhead selects for one result predicate as its complement. In order to make our claim, we provide novel data that violate the Unique Path Constraint defined as a semantic constraint. Further, we analyze examples that at first blush pose a problem for the present account as they appear to involve two result phrases, e.g.,shot him dead off the horse. We argue, however, that the second result phrase is not syntactically a result, but rather constitutes a case of what Acedo-Matellán, Víctor, Josep Ausensi, Josep Maria Fontana & Cristina Real-Puigdollers. forthcoming. Old Spanish resultatives as low depictives. In Chad L. Howe, Timothy Gupton, Margaret Renwick & Pilar Chamorro (eds.),Open romance linguistics 1. Selected papers from the 49th linguistic symposium on romance languages. Berlin: Language Science Press have called low depictives, which join the syntactic derivation through a low applicative head.
Simultaneous neutron powder diffraction and Raman spectroscopy – an approach of combining two complementary techniques
Authors: Finger Raphael , Hansen Thomas C. , Kohlmann Holger
Published: November 2021

Diffraction techniques are well-established methods for crystal structure determination as well as phase identification and quantification. Raman spectroscopy can be a valuable complementary characterization technique, because in contrast to the former it yields also information on amorphous materials and it is a probe for short-range structural effects. The herein presented setup allows for simultaneous neutron diffraction and Raman spectroscopy, shown with a sample of lead sulfate under ambient conditions as a proof of principle. In order to fulfil requirements of both methods, a sapphire single-crystal is used as a sample holder. Practical considerations for successful simultaneous in situ neutron diffraction and Raman spectroscopic measurements are given.
Effects of Strength Training on Blood Pressure and Heart Rate Variability—A Systematic Review
Authors: Corso Marcelo , de Figueiredo Tiago C. , Carvalho Danilo , Brown Amanda F. , de Salles Belmiro F. , Simão Roberto , Willardson Jeffrey M. , Dias Ingrid
Published: November 2021

Strength training (ST) has been studied for acute and chronic effects on blood pressure (BP) and heart rate variability (HRV). These effects have never been reviewed collectively concerning the variables that comprise a ST program. Therefore, this review aims to examine the manipulation of ST variables (i.e., load intensity, number of sets and repetitions, exercise order, and rest interval length) on BP and HRV after a session and a long-term program. The BP reduced significantly after an ST session independently of the load intensity, the number of sets and repetitions, the rest interval length, the mode, and the participant characteristic (healthy patients or patients with chronic disease). However, a high number of sets and repetitions, prioritizing multijoint exercises, with longer rest interval lengths between sets and exercises may potentiate these effects. In the HRV analyses, most of the trials showed a sympathetic predominance after an ST session. Hence, it is reasonable to confirm that central adjustments are responsible to control hemodynamics after an ST session.
Effect of Repetition Duration—Total and in Different Muscle Actions—On the Development of Strength, Power, and Muscle Hypertrophy: A Systematic Review
Authors: Moreno-Villanueva Adrián , Pino-Ortega José , Rico-González Markel
Published: November 2021

The aim of this systematic review was (a) to identify the articles that have differentiated muscle action duration (MAD) in the eccentric (ECC) and concentric (CON) muscle action regimen during resistance training (RT) programs and (b) to analyze how MAD affects strength, power, and muscle hypertrophy adaptations. Twenty-four studies were included from 3 electronic databases. The results showed that the RT protocols with medium ECC MAD and fast CON MAD, specifically cadences 2–4/0/1/0, produced the highest improvement values for the development of maximum dynamic strength, both in trained (18–24%) and untrained subjects (10–14%). For the development of maximum power, a medium total repetition MAD of less than 4 seconds and slow total repetition MAD, less than 8 seconds, seems suitable for untrained and trained subjects, respectively, with the condition that CON MAD is explosive or fast (cadence 4–8/0/max-3/0). Finally, muscle hypertrophy could be improved with a total repetition MAD less than 8 seconds in both trained and untrained subjects. The optimal timing of each muscle action to maximize hypertrophic training results is still not entirely clear. In conclusion, the prescription of the MAD, total and phase specific, should be planned according to the adaptations desired in untrained and trained individuals.
Cytologic Categorization with Risk Stratification of Endoscopic Ultrasound-Guided Fine Needle Aspiration from Pancreatic Lesions Based on Guidelines of the Papanicolaou Society of Cytopathology: 12-Year Tertiary Care Experience
Authors:   Department of Pathology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, UP, India, Nishith Nilay , Rao Ram Nawal ,   Department of Pathology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, UP, India, Rai Praveer ,   Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, UP, India
Published: November 2021

Background and Aims: Pancreatic malignancy is an important cause of cancer mortality worldwide. Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) plays a crucial role in the pre-operative diagnosis of pancreatic lesions. In this study, we have analyzed the cytological spectrum of pancreatic lesions in the Indian population over 12 years, categorized them according to the Papanicolaou Society of Cytopathology System for Reporting Pancreaticobiliary Cytology (PSCPC), and assessed the risk of malignancy (ROM) for each of the categories. Methods: A computerized data search from January 2008 to December 2019 revealed 581 pancreatic EUS-FNA samples, among which surgical follow-up was available for 73 cases. All cytological specimens were reviewed and prospectively classified into one of the six diagnostic categories proposed by the PSCPC. Subsequently, a cyto-histological correlation was performed and the ROM was calculated for each category. Results: The cytologic diagnoses included 50 non-diagnostic (category I), 175 negative for malignancy (category II), 19 atypical (category III), 27 neoplastic:benign (category IVA), 30 neoplastic:other (category IVB), 26 suspicious (category V), and 254 malignant (category VI) cases. ROM for non-diagnostic aspirates, non-neoplastic benign specimens, atypical cases, neoplastic:benign, neoplastic:other, suspicious for malignancy, and the malignant category was 16.7%, 7.1%, 33.3%, 0.0%, 20.0%, 100%, and 78.6%, respectively. Conclusion: We document an increased risk of malignancy from category I to category VI of the PSCPC. The malignancy risk for category VI (malignant) was statistically significant in our study but was lower in comparison to the values reported by other authors. Nonetheless, such an approach would establish transparent communication between the pathologist and the clinician, as well as aid the clinician in decision making, particularly in intermediate categories.
Dynamic Response of Deck Pavement of Continuous Box Girder Bridge with Variable Section Corrugated Steel Webs under Moving Loads
Authors: Xin Su , Chundi Si , Taotao Fan , Xinzhen Gao , Yuefeng Zhu , Song Li
Published: November 2021

To analyze the dynamic response of the deck pavement of continuous box girder bridge with variable section corrugated steel webs (CBB) under moving loads, a three-dimensional (3D) finite element model of three-span CBB superstructure was established using the finite element software ABAQUS. The validity of the 3D finite element model was verified by the field static load test data. Five vehicle speeds (40 km/h, 60 km/h, 80 km/h, 100 km/h, and 120 km/h), four types of axle loads (5 kN, 25 kN, 30 kN, and 40 kN), and three kinds of load positions were selected. The dynamic responses of the CBB deck pavement, displacement, stress, acceleration, and impact coefficient were calculated. The results showed that under the action of moving loads, the maximum values of vertical displacement and vertical stress appeared on the top surface of deck pavement. The longitudinal shear stress of deck pavement of CBB increased with the increase of pavement depth, and it reached the maximum value at the top of concrete pavement. With the increase of vehicle speed, the impact coefficient, vertical displacement, and transverse stress of the top surface of deck pavement gradually decreased, which indicated that the stress of deck pavement was significantly impacted by the vehicle speed and axle load, while its vertical displacement was less influenced. Under the eccentric load, the large transverse torsion would be produced in the CBB and the more the load deviates from the centerline of the cross section of the CBB, the greater the vibration amplitude of the vertical acceleration generated by the mid-span node on the surface of the deck pavement. Therefore, the low vehicle speed and eccentric load had a great impact on the structural safety response of deck pavement. In practical engineering, it is necessary to avoid vehicles driving at low speeds on one side of the bridge.
Interpolational $(L,M)$-rational integral fraction on a continual set of nodes
Authors: Baranetskij Ya.O. , Demkiv I.I. , Kopach M.I. , Solomko A.V.
Published: November 2021

In the paper, an integral rational interpolant on a continual set of nodes, which is the ratio of a functional polynomial of degree $L$ to a functional polynomial of degree $M$, is constructed and investigated. The resulting interpolant is one that preserves any rational functional of the resulting form.
Approximation of functions of several variables by multidimensional $S$-fractions with independent variables
Authors: Dmytryshyn R.I. , Sharyn S.V.
Published: November 2021

The paper deals with the problem of approximation of functions of several variables by branched continued fractions. We study the correspondence between formal multiple power series and the so-called "multidimensional $S$-fraction with independent variables". As a result, the necessary and sufficient conditions for the expansion of the formal multiple power series into the corresponding multidimensional $S$-fraction with independent variables have been established. Several numerical experiments show the efficiency, power and feasibility of using the branched continued fractions in order to numerically approximate certain functions of several variables from their formal multiple power series.
Asymmetric circular graph with Hosoya index and negative continued fractions
Authors: Komatsu T.
Published: November 2021

It has been known that the Hosoya index of caterpillar graph can be calculated as the numerator of the simple continued fraction. Recently in [MATCH Commun. Math. Comput. Chem. 2020, 84 (2), 399-428], the author introduces a more general graph called caterpillar-bond graph and shows that its Hosoya index can be calculated as the numerator of the general continued fraction.

In this paper, we show how the Hosoya index of the graph with non-uniform ring structure can be calculated from the negative continued fraction. We also give the relation between some radial graphs and multidimensional continued fractions in the sense of the Hosoya index.
Effects of the molding process on properties of bamboo fiber/epoxy resin composites
Authors: Shi Jiangjing , Zou Yanping , Zhang Wenfu , Chen Hong
Published: November 2021

Filament winding is an advanced technology for fabrication of high-performance composites. Pressure-free fabrication can be achieved for non-planar composites with complicated shapes using resin-immersed twisting fibers. In this study, twisted bamboo fiber (TBF) composites were prepared by a filament winding processing (FWP). Short bamboo fiber (SBF), long bamboo fiber (LBF), and TBF composites were prepared by hot pressing (HP) and resin transfer molding (RTM). The results showed that the bamboo fiber/epoxy resin composites were positively related to the fiber size. The bamboo fiber/epoxy resin composites fabricated by FWP exhibited optimal shear performance, while those generated by RTM exhibited optimized bending performance. Dynamic thermomechanical analysis revealed that composites made by FWP had optimized interfaces. The FWP mechanism of bamboo fiber composites was resin immersion and alignment of TBF; upon resin immersion the TBF were coated by resin and could not enter the internal tubes or parenchyma tissues of the TBF. The TBF was aligned by winding equipment. After heated solidification of the resin, several bubble pores were distributed on both sides of the TBF, whose positions remained static over time. The filament winding processing for bamboo fiber composites enhanced their performance and could lead to the applications in bamboo fibers composites.
Relationship of tracheid length, annual ring width, and wood density in Scots pine (Pinus sylvestris L.) trees from different social classes of tree position in the stand
Authors: Fabisiak Ewa , Fabisiak Beata
Published: November 2021

This study investigated the relationship between the length of the tracheids, the width of annual rings, and the wood density of Scots pine (Pinus sylvestris L.) obtained from the dominant, intermediate, and suppressed classes of a 60-year-old stand. Measurement of tracheid length was performed on the material macerated from the following annual rings: 3, 6, 9, 12, 15, and thence every 5 annual rings. Basic density was determined on samples that included five annual rings from the core to bark. Tree position in the stand had a significant impact on the examined properties of wood. In a given biosocial class, tracheid length decreased as the width of annual rings increased. As the biosocial position of a tree in the stand improved, the length of the tracheids increased, and wood density decreased. In wood of the same density range, the increment in tracheid length was the greatest in wood of dominant trees and the lowest in wood of suppressed trees.