bluuebunny/crossref_metadata_2025 huggingface dataset:
Effect of omeprazole on reproductive hormonal levels and sexual function in male patients with peptic ulcer disease
Authors: A-J Thanoon Imad , Qusay Mahmood Ala'a
Published: January 2024

Objectives: To assess the effects of Omeprazole at a fixed dose on sexual function (by self reporting questionnaire) and serum levels of testosterone, prolactin, follicle stimulating hormone (FSH), luteinizing hormone (LH), and estradiol (E2) in newly diagnosed male patients with peptic ulcer disease, in comparison to healthy controls. Patients and Methods: Patients were received and interviewed in Ibn- Sina Hospital, out-patient clinic, medical section and were selected  according to certain criteria. From 60 male patients selected only 43 completed the follow-up study. Initially sexual function were assessed using a self-reporting questionnaire and a blood samples were taken with assay of serum testosterone, prolactin, FSH, LH and E2 using Minividus technique. Patients than put on Omeprazole therapy 20mg twice daily for 45 days with Clarithromycin 500mg twice daily and Metronidazole 500mg twice daily for the initial 10 days. By the end of the suggested period of follow-up, sexual function were assessed by self-reporting questionnaire and other blood samples were taken with assay of serum testosterone, prolactin, FSH, LH and E2 using the same analytical technique. Included in this study also forty apparently healthy age, matched male volunteers as a control group . Blood samples were also withdrawn from them and assay of serum testosterone prolactin, FSH, LH and E2 were done , with assessment of sexual function using the same self reporting questionnaire. For both groups ( the patients and controls), body mass index were calculated using special equation. Results:There was insignificant differences in the parameters of sexual function between patients with peptic ulcer disease in the pre-therapy stages and the controls, so as in the serum levels of testosterone, prolactin, FSH, LH and E2. After therapy there was a significant differences in the mean serum level of testosterone from the pre-therapy stage and the controls, with insignificant differences in the sexual function parameters and serum levels of prolactin, FSH, LH and E2.Conclusion: Long term Omeprazole therapy might cause a reduction in the level of testosterone hormone with insignificant effects on other sexual hormonal levels (prolactin, FSH, LH and E2) within significanteffect on sexual function, in male patients with peptic ulcer disease.
BCG & tuberculin induced experimental lapin secondary cryoglobulinemia
Authors: M. Shnawa Ibrahim , Abdulla Jassim Yazi
Published: January 2024

BCG and tuberculin were used as a possible immune stimulants for cryoresponses in a lapin model .Immunization and hyperimmunization protocols both for primary and secondary cryoimmune response were attempted .Cryocrit percentage ,protein nature through biurete reaction , ratio of cryoglobulin to total globulin of immune and hyper immune sera as well as reversible precipitable at 4c ,and solubility at 45c were identification criteria for cryoglobulin. Both BCG and tuberculin 0.05IU were found good stimulants for cryoresponse . The cryoglobulinemia was found associated and non associated with IgM anti IgGautoantibody (RF) in tuberculin case while, it was non RF associated in the case of BCG. BCG and tuberculin induce secondary mixed cryoglobulinemia of IgM-IgG-IgA type. The proposed classification was II-III class. This model stands as supportive model to the natural human mixed cryoglobulinemia associated with Pulmonary tuberculosis.
Toxoplasmosis among schizophrenic patients in Al-Rashad Teaching Hospital
Authors: Shabat Jassam Fadheelah , N. Younis Fekri , A. Hassan Mohammed , A. Abdulghani Emad , D. Jassam Mohammed
Published: January 2024

Background;Studies showed that people with schizophrenia and other mental disorders have a higher incidence of exposure to T.gondii. The aim of the present paper is to estimate the rate of toxoplasmosis in schizophrenic patients.Methods;A total of (125) serum samples were studied.(100) patients from AL- Rashad Teaching Hospital compared with (25) healthy person as a control group; during the period from October 1,2009- March31,2010. All were male of age (20-55 years).Serum samples were tested by using ELISA Toxoplasma technique for Ab. detection (IgG and IgM) in addition to the serum testosterone concentration.Results;The results showed that 49% schizophrenics have IgG positive Toxoplasma ,6% have positive IgM and 4% have both IgG and IgM positive Toxoplasma .The risk of having schizophrenia in subjects with positive IgG Ab is 5 times higher than negative IgG Ab persons. The mean IgG Ab. titer was higher (1.1) in schizophrenics. The serum testosterone concentration was significant (6.1)in schizophrenics & was significantly higher in schizophrenics with positive IgG Ab.(7.1). No associations were found between toxoplasmosis and residence, smoking, alcohol consumption, educational level, history of contact with cats, or marital status.Conclusion;Schizophrenics have IgG positive Toxoplasma , high IgG Ab titre & serum testosterone concentration.
Lipid profile and pre â€“ eclampsia
Authors: Chafat Karawn Eman , Abdul-Hadi Ahlam
Published: January 2024

Objective: To assess if there are changes in lipid profile in preeclampsia and if these changes can be used as marker of severity of the condition.Study design: This study include 100 pregnant women divided into 3 groups.1) 25 pregnant women with sever pre-eclampsia in the third trimester.2) 25 pregnant women with mild-moderate pre-eclampsia in the thirdtrimester .3) 50 apparently healthy pregnant women of comparable age &parity in the third trimester. All were investigated for serum lipid profile includingserum cholesterol(CH)serum triglyceride(TG)serum high density lipoprotein(HDL)serum low density lipoprotein(LDL)serum very low density lipoprotein(VLDL)

Result: There was significant increase in serum TG ,VLDL and LDL level in women with pre -eclampsia than the control group and no significant difference in the serum cholesterol, while patient with preeclampsia had lower HDL level. When we compare patient with sever pre-eclampsia with patient with mild pre - eclampsia we found that women with sever pre -eclampsia has significantly higher level of TG and VLDL only.
Effect of evening primrose oil on primeralary blood coagulation investigation in male rabbits
Authors: Hasan Sahib Zena , A.Latif A.Razzak , Naji Abdullah Hussien
Published: January 2024

This study was performed to determine the effects of Evening primrose oil (EPO) on haemostatic parameters following 30 and 60 days administration of 90 mg/kg (EPO) to healthy male rabbits. The laboratory resulting in significant increase in Prothrombin time (PT), activated partial thromboplastin time (aPTT) assays (p<0.01), platelets count significantly decreased (p<0.01) at both times. While fibrinogen concentration are insignificantly decreased. These effects might be due to inactivation or inhibition of factors affecting coagulation.
Comparative study between the usage of transurethral diversion and suprapubic cystostomy after distal hypospadias repair by tubulerized incised urethroplasty
Authors: A. Maazil Ali , Gali Saadaldeen
Published: January 2024

Objective:-to compare the usage of transurethral urinary diversion and that of suprapubic cystostomy after distal shaft hypospadias repair by tubulerized incised urethroplasty.Method: - between December 2008 to October 2010 a 48 boys who had primary hypospaidais under went surgical repair by tubulerised incised urethroplasty, they divided into two groups according to the type of urinary diversion that used post operatively; group A with suprapubic diversion and group B with transurethral nasogasteric tube diversion.Result: - 48 boys aged between 3-21years with hypospadais had divided in to two equal groups according to type of post operative urinary diversion (suprapubic and transurethral), the distribution of hypospadais type similar in both groups. Urinary diversion was more effective , post operative complication were rare ,no trigon irritation and excellent cosmetic result (100%) were recorded following transurethral diversion with nasogasteric feeding tube ,conversely the creation of suprapubic cystostomy increased incidence of trigon irritation (12.5%) and fistula formation( 4.17 %).Conclusion: - transurethral urinary diversion was very effective and gave better result than suprapubic cystostomy in distal type hypospadias repair.
Effect of carvedilol on echocardiographic ejection fraction and fraction shortening in doxorubicin treated females with breast cancer
Authors: Mahdi Hashim Hashim , Ahmad Al-Zubaidy Adeeb , Hassan Abboud Al-Rekabi Sameer
Published: January 2024

Background : Doxorubicin based regimen is the most common treatment of breast cancer which is highly complicated by cardiotoxicity.Aim : To clarify the possible effects of carvedilol on echocardiographic ejection fraction and fraction shortening in doxorubicin based regimen in females with breast cancer.Patients and Methods : A total of 16 females with breast cancer were included in this study. The patients were randomized into 2 groups , 8 patients each. Group I included patients were treated with doxorubicin based regimen for 6 cycles with 21 day apart. Group II included patients were received doxorubicin based regimen with carvedilol 3.125 mg , orally , twice daily for 5 days , for 6 cycles. Echocardiography was done to measure ejection fraction and fraction shortening at zero time and 3 days after 2nd , 4th and 6th cycles.Results: Treatment with CAF regimen caused highly significant decrease in echocardiographic ejection fraction and fraction shortening after 2nd , 4th and 6th cycles in comparison to baseline readings ( P < 0.01 ). Combined CAF + Carvedilol 3.125 mg orally twice daily for 5 days caused highly significant increment in echocardiographic ejection fraction and fraction shortening compared with that of CAF regimen group ( P < 0.01 ).Conclusion: Carvedilol causes significant increase in echocardiographic ejection fraction and fraction shortening in doxorubicin treated patients.
The relationship between incompletely excised basal cell carcinoma and recurrence rate
Authors: Miri Saadoon Ahmed , Rasool Hussein Aws
Published: January 2024

Objective :To define the relationship between margin of clearance at sites of excision and the recurrence rate of basal cell carcinoma in head and neck regionMethods: This study was conducted on 65 patients in Al-Diwanyia teaching hospital who underwent surgery for basal cell carcinoma in the head neck region between 2007 and 2008 and followed up for a period of 3 years .The patients were evaluated according :site and type of Bcc ,whether or not the excision was complete ,tumor recurrence , gender and age of the patients . The size of tumor was less than 2cm in all patientsConclusion: a risk of recurrence in incompletely excised basal cell carcinoma was more common in younger age group patients and we recommend close clinical follow up for other patients .
Clinical Outcomes improvement of refractory Obsessive compulsive disorder by use Olanazapine
Authors: Mohammed Farhan Hafidh
Published: January 2024

More than half of the patients with obsessive- compulsive disorder(OCD) remain unimproved by Serotonin-Reuptake inhibitors(SSRI). objective of this study was to examine whether addition of atypical antipsychotic (olanzapine ) to Sertraline is useful for patients with OCD who do not respond to SSRI monotherapy.1. According to (DSM IV-TR criteria) , 20 patients are diagnosed asOCD and did not responded to Sertraline at dose 100-150mg/day2. Olanazapine was additional treatment , start 2.5mg/day at first monththen 5 mg/day for last two months of study

 3. Treatment response was assessed using the Yale-Brown Obsessive- Compulsive Scale (YBOCS) at end of each months of study 16 of 20 patients respond to the olanzapine augmented sertraline therapy .

The mean baseline YBOCS score of 32.75 dropped to a mean of 21.75 at endpoint for male with reduction 12.81% from baseline. While in female, the mean baseline YBOCS score of 33.83 dropped to amean of 21.67 at endpoint with reduction 17.06% from baseline. Treatment-refractory OCD Patients may benefit from addition of olanzapine to ongoing SSRI therapy.
Perifollicular vascularity as a potential variable affecting outcome in stimulated intrauterine insemination treatment cycles: by using transvaginal power Doppler
Authors: Shamkhi Al-Ghazali Basima , R. Al-Haris Nada
Published: January 2024

The aim of study was to asses any potential relationship between perifollicular vascularity and fetal outcome in an invivo environment following ovarian stimulation and intrauterine insemination. A total of 75 unselected consecutive patients undergoing stimulated intrauterine insemination cycles (with clomid) was recruited where the perifollicular vascularity of the follicles â‰¥16 mm was studied using subjective grading system by transvaginal power Doppler ultrasonography 24 h after HCG administration. 36 hours after H.C.G administration we did intrauterine insemination and two weeks later we did pregnancy test for our patients. A total 75 mature follicles ( > 16 mm ) was studied. According to the result of Doppler study we found that we had 54.6% of follicles having grade III perfollicular vascularity , 32% having grade II , and 13.3% grade I. The follicles of high grade vascularity were associated with higher pregnancy rate (grade 3= 19.5%) than cycles with low grade vascularity (grade2 =12.5%), with no pregnancy occur in grade 1 vascularity group. Early pregnancy loss rate was significantly higher in grade2 follicular vascularity (33.3%) than grade 3 (12.5%) . The mean age and duration of subfertility were significantly higher (P<0.05), with low follicular vascularity grades compared with grade II, III. These data would suggest that perfollicular vascularity and PI (pulsatility index ) of uterine artery has an important role to play in the outcome of IUI cycles. And that the power Doppler has the potential to refine the management of assisted reproduction treatment cycles.
Nonalcoholic Steatohepatitis;N.A.S.H In Babil Governorate
Authors: M. Kadhim Thamir
Published: January 2024

Fatty liver is a well known cause of sudden death. It could affect any one with different etiologies, alcohol ,metabolic, drugs, poisons, pregnancy, obesityâ€¦etcObjective:To demonstrate the extent of such defect among general population in order to correct it by elimination the cause and the promising treatment. Patients and materials: A hundred cadavers referred to the Forensic pathology department in the Babil Health Directorate were examined from the 1st of April 2007 to the 1st of April 2008, 65 males, 35 females fall in the category of the violent death .Alcoholics, diabetics, obese, pregnant, and those who were in the both extremities of age were excluded.Result: A mild type of fatty changes was found in eight cadavers (5 males, 3 females) not associated with hepato or spleenomegaly.
Measurement of serum lipids and lipoproteins in children as a risk index for cardio vascular diseases in adulthood
Authors: A. AL-Kafagi Akeel
Published: January 2024

Many diseases and metabolic abnormalities are take place as result of increase lipids and lipoprotein in the blood. Cardiovascular events are the most common disease in this regard. The aim of this study is to determine the level of cholesterol, triglycerides, high density lipoprotein cholesterol and low density lipoprotein cholesterol in children as a risk index for cardiovascular diseases in adulthood. To achieve this aim , the study was evaluate the effect of weight, family history and health status for children on the level of the lipids and lipoproteins. The result revealed significant increase in the level of lipids and lipoproteins (cholesterol and triglycerides) in the over weight children when compared with normal kids. While no clear effects were observed in the scale of lipids and lipoprotein values with regard to the family history and the health status issues. The outcome indicate that increase in the concentration of cholesterol and triglycerides in the over weight children are the main directing consideration for the cardio vascular diseases in the adult. Further more the follow up ,the screening for the intensity of lipids and lipoproteins and the early therapy for hyperlipidemia will certainly decrease the incidence of future cardiovascular disease.
Determination of Hepatitis C Viral Load and Genotypes by Real-Time and RT-PCR at Thi_Qar Province
Authors: A. Abbas Yahya , H. Aubaid Adnan , J. Hamad Bushra
Published: January 2024

The present study was carried out from Sept. 2010 to Jul. 2011 to detect the viral load and genotypes of HCV infections among asymptomatic peoples and patients referred to the central blood bank, center of thalassemia /AL-Haboby Hospital, renal dialysis unit/Al- Hussein Teaching Hospital and public health laboratory at Thi-Qar province.

Real-Time Polymerase Chain Reaction Technique (RT-qPCR) was implemented on 90 individuals of anti-HCV seropositive by ELISA III assay. The results revealed that 51(56.66%) were gave positive results for HCV. The RT-qPCR analyses of the positive samples were showed that the viral loads were ranged from 1.19 Ã— 103 to 4.3 Ã— 106 IU/ml of blood .The mean of viral load was 5.9 Ã— 105 IU/ml of blood, whilst, the median was 2.6 Ã— 105 IU/ml. Three genotypes of HCV were detected in patients serum by RT-PCR technique. Genotype 1a (33.33%), genotype 1b (37.25%) and genotype 4 (86.27%) with significant differences (p>0.05). Genotype 4 was the predominant and found in 44 of 51 cases, of those 21(41.18%) as single infections. Mixed infections with genotype 4 and each of 1a and 1b was found in 21.57% and 11.76% respectively. Mixed infections with genotype 4 and both 1a and 1b was found in 11.76%. Single infections with genotype 1b only was found in 13.73%, while genotype 1a was detected only in mixed infections. This study was the first at Thi-Qar province which involved the searching for HCV viral load and genotypes by using of Real-Time and RT-PCR technique.
Left handed simple, recognition and choice reaction times
Authors: Ibrahim Riah Khalid
Published: January 2024

In this study, 27 left handed healthy volunteers (12 male and 15 female) aged between 18 and 23 yrs were included in reaction time (RT) test that include simple reaction time (SRT), Recognition reaction time (RRT) and Choice reaction time (CRT). Itâ€™s appeared from the results that, SRT for the central target colors was less than for the peripheral on white and black background. The individual ability in recognizing the colored targets depends on the contrast of these colors with the background, when the contrast increased the individual ability to response increase. Two back targets RRT for individuals were longer than one back targets. Using the two hands together for individuals produces a faster CRT than using one hand only.
Epidemiological study in roseola infantum in Babylon
Authors: Hassan Noor Muder , Hamzah Hamad Wisam , Jabbar Hussein Adil
Published: January 2024

Roseola is a mild febrile exanthematous illness occurring almost exclusively during infancy. Among the many alternative names for the disease are exanthem subitum (indicating the sudden and surprising appearance of the rash), the rose rash of infants and pseudo-rubella. Human herpesvirus 6 (HHV-6) is the etiological agent of roseola infantum. The aim of this study is to predict the disease early by the time of high incidence of this disease, the common age of presentation and the commonest clinical findings. A cross-sectional study was conducted in Babylon Teaching Hospital for Maternity and Children in Babylon city for 12 months, from the 1st March 2009 to the 1st February 2010. The study involved 48 cases of roseola who visited the outpatient clinic which were followed up for 3 days (22 cases were admitted to hospital and 26 cases were reevaluated after a second visit). In the result of this study we found roseola was highest in infants with age group 10-12 months. The cases in urban area is more than rural area, it occur more in the period from April to June. There was no significant sex predominance in the incidence of the disease. The most common clinical finding were occipital lymph node enlargement in all cases (100%) and cervical lymph node enlargement in (89.6 %) infants.
Upper Respiratory tract infection in breast feed baby versus formula feeding
Authors: Raji Jallab Hassan
Published: January 2024

Four hundred thirty three children has attending the health center of Jordan university of science and technology for a period between (Nov 1st â€“Nov30th) 2009.100 of them complaining of upper respiratory tract infection which included in this study . We studied the effect of feeding types on the frequency of upper respiratory tract infection , the children who exclusively fed for the 1st 6 months of life had lower rate of upper respiratory tract infection compared to bottle feeding . A strong association was found for protection against upper respiratory tract infection by breast feeding versus bottle feeding .The collection of data were prospective based on valid questionnaires and methodologies. Our finding supports the hypothesis that predominant breast feeding protecting against occurrence of upper respiratory tract infection , additional large controlled clinical trials are required to confirm these findings and to understand mechanism of breast milk protection .
Effect of Amlodipine drug on male sex hormones of hypertensive patients in Al-Najaf province
Authors: Saleem Zayed Al-Shebli Karrar
Published: January 2024

The current study was carried out in Al-Sader teaching Hospital in Al-Najaf province during the period 2011/6/5 till 2011/12/2. The study was undertaken to evaluate the effect of Amlodipine drug thatâ€™s uses to treatment of hypertension on male sex hormones (LH ,FSH and testosterone) in a number of males hypertensive patients . Forty five males patients who are took this drug to lower their high blood pressure participated in the study , their ages ranged from (31-60) years divided into three groups (15 male/group) according to amlodipine doses 2.5, 5 and 10 mg once daily .Also contribute fifteen health males as a control subjects, their ages ranged from (30-63) years. Results of the study revealed a significant decreased of LH, FSH and testosterone activities in a patients who are treated with two highly doses of amlodipine when compared with control group, also when compared high dose group with low dose group. Regarding the effect of different ages of male hypertensive patients who are treated with amlodipine on these hormones , the findings were indicated a significant decreased of these hormones levels at the highest ages especially at 51-60 years old. On the other hand, the results obtained there were an effect of interaction between different doses of amlodipine and ages of hypertensive patients that treated with it on male sex hormones levels particularly at the higher doses and ages , and this effect was represented by decreased of these hormones levels. The study was suggested that the therapy with amlodipine may be causes defect in male reproductive system that indicated by inhibition of male sex hormones levels and this effect was amlodipine doses and patients' ages dependent.
Bromocritine Treatment in Infertile Population of Women with Galactorrhea
Authors: S. Al-Quizwini Taghreed
Published: January 2024

Galactorrhoea ( a non-physiological production of milk) can be found with or without raised levels of serum prolactin . Prolactin is the hormone that stimulates milk secretion and cause luteal phase disturbance. Thus galactorrhrea can ead to infertility which is one of the most common gynecological problems of women attending gynecological clinics .All patients included were showing galactorrhea and all were complaining of infertility.The patients were collected from the infertility clinic in the maternity teaching hospital in Al-diwaniah city ,and from private clinics from Oct 2009 to June 2001 and according to strict inclusion criteria, that eliminate other causes of infertility other than presence of galactorrhea and eliminate risky conditions that may exacerbate upon the use of the drug bromocriptine. The total number of patients was 227.

Fasting serum prolactine was examined for each patient and all patients were started on treatment with Bromocripine ( a dopamine agonist ) orally of 1.25 mg or at half tab a day on a fixed dose. The patients were grouped into two groups according to their levels of fasting serum prolactine, group A(G A) had high levels above normal serum prolactine gathering 87 patients and group B(G B) had normal serum prolactine levels gathering 120 patients. Twenty patients were out of the study being either missed from follow up or excluded for risk or for severe side effects. Each patient was followed up for 12 month from the initiation of the treatment or until appearance of response ,which one being earlier.Accumulative pregnancy rates were followed for the two groups in one year following treatment. The result was ( 89.8 % of patients of GA ), and 76.6% of patients of GB ).Although the difference is significant the accumulative pregnancy rate was significant in group B too. Conclusion: In infertile women with galactorrhea, we suggest treatment with bromocriptine in these patients regardless of serum prolactin level.
Identification of bacterial agentsand antimicrobial susceptibility of neonatal sepsis with patient,s outcome
Authors: Mohammed Ali Abdul-Kareem , Abdul-Kareem Lamia , Japur Rashed Emad
Published: January 2024

Background : Sepsis neonataroum is an important factor for morbidity and mortality in neonates. The incidence of neonatal bacterial sepsis depends on geographic area and may vary from country to country as well as within the same country.Objective: To identify the percentage of neonatal septicemia confirmed by positive blood cultures among 664 neonates admitted in neonatal care unit, and to identify the bacterial agents causing early and late neonatal sepsis and their antimicrobial susceptibility, and the outcome from neonatal septicemia. Patients and methods: The total number of patients(with clinical signs and symptoms suggesting sepsis) collected from neonatal care unit of ALKadimiya Teaching hospital from the 1st of January to the end of october 2011 were 664 neonates, and only 105 neonates who show signs and symptoms suggestive of septicemia that were confirmed by a positive blood culture were enrolled in this study. Data were collected include :Gestational age, Birth weight , Gender, Onset of sepsis, Place of delivery and also we followed up the subjects and recorded the outcome till discharge.Results: In this prospective study and from 664 neonate were admitted (total number of admission), positive blood cultures were obtained for 105 neonates (15.8%). Gram negative bacteria were the commonest causative agent in both early (66.7%) and late (56.9%) onset sepsis. Among neonates with sepsis, 33 patients (31.4%) had early onset and 72 patient (68.6%) had late-onset neonatal sepsis. The susceptibility of the isolated causative agent to selected antibiotics were the same in early and late onset sepsis. Over 70% of gram negative bacilli were resistant to both ampicillin and cloxacillin but show variable sensitivity to gentamicine and cefotaxime. Most of the isolated gram positive bacteria were sensitive to ampicillin, cloxacillin and cefotaxime but highly resistant to gentamicin. The death rate was 20.9%. Early onset sepsis, male gender, gestational age less than 37 weeks and birth weight less than 2500 gm were found to be significantly associated with death.Conclusions: Gram negative bacteria were the main cause of early and lateonset neonatal sepsis in our center and many of these isolated bacteria were resistant to the used antibiotics. Low birth weight neonates <2500 gm, gestational age < 37weeks, male gender and early onset sepsis were significantly associated with death. The death rate due to neonatal sepsis was higher compared with the other studies.

Recommendations: Proper antenatal care and optimal obstetric management in early detection and treatment of mothers at risks together with minimizing invasive procedures of infants as much as possible and ideal nursery setup which includes adequate space for care of infants and aseptic equipments for monitoring.
Effect of metformin on pregnancy outcomes in women with PCOS
Authors: A. Swadi Asma , M.Swadi Saba
Published: January 2024

Background: Recurrent pregnancy loss (RPL) classically refers to the occurrence of three or more consecutive losses of clinically recognized pregnancies prior to the 20th week of gestation (ectopic, molar, and biochemical pregnancies are not included). we hypothesized that metformin owing to its metabolic, endocrine effect may reduce the incidence of first trimester miscarriage in PCOS women. Materials and Methods: We examined the records of all 82 nondiabetic women with the polycystic ovary syndrome who became pregnant while being seen in the out patients Clinic of the maternity teaching hospital and private clinic in AL-Qadisyiah city between January 2011 and march 2014, and who did receive metformin 3 months pre-conception (group1; n = 37) in contrast to second group who became pregnant while taking metformin and continued taking metformin at a dose of 1000â€“2000 mg daily throughout the first 20 weeks of gestation(group2; n = 45).Results: both groups were similar with respect to all background characteristics (age, BMI, parity, RBS, blood urea and serum creatinin).rates of early pregnancy loss in group1(82.5%) compared with (79.7%) in group2.after administration of metformin; pregnancy loss was( 83.7%,15.5%) in group1 and group2 respectively (P value = 0.001).Conclusion: administration of metformin in the first 20 weeks of pregnancy to women with PCOS was associated with a marked and significant reduction in the rate of early pregnancy loss.
Identification of Cryptosporidium Antigens in Stool Specimen Using Enzyme Linked Immunosorbent Assay (ELISA) in Al- Diwanyia Province- Iraq
Authors: Al-Omashi Ghada
Published: January 2024

One hundred fifty six of stool samples were collected from patients suffering form diarrhea; the samples were classified according to the rural and urban areas, gender, age and immune status (pregnancy, diabetes, and corticosteroid therapy). Routine parasitological examinations were done to all samples using acidfast stain technique. Antigens detection method was also done by using ELISA. The acid fast technique results showed that 23 /156 (14.7%) were positive cases for identify Cryptosporidium oocyte in stool specimen, while the ELISA showed 82/156 (52.5%) were positive cases for identify Cryptosporidium antigen in stool specimen. The rural areas showed higher positive cases(17.5%) than urban areas and males' positive cases were higher results ( 18.7%) than females, while the results showed that lowest positive case were in age group 16-20 years (5.2%) and the highest case were in age group less than 5years (29.4%). Immune status (pregnancy, diabetes, and corticosteroid therapy) of patient showed an important role in the cases disruptions of the infection with Cryptosporidium spp.(17.6%, 29.8 % 27.6 %) respectively. The sensitivity, specificity of ELISA for identification Cryptosporidium antigens in stool specimen in comparison with the modified acid-fast staining method were determined 95%, 100% respectively, so it can be concluded that acid-fast technique which can be used as a referential diagnostic method has some limitations while the ELISA is more sensitive and specific for identification of the parasite antigens in stool specimens.
Maternal satisfaction of pediatric care providers for children with chronic diseases
Authors: F. Mussa Russul , A. Alyasiri Adeebah , M. Al-Marzok Jasim
Published: January 2024

Background: Children with chronic illnesses need continuous correlation with pediatrician. Assessment of patient satisfaction allows health care providers to explore the extent to which their service meets the needs of their patients. Interview techniques are important for explanation of the problem to the family. The pediatrician deals with respect to the parent's ideas to improve their self-esteem and competencyObjective: To assess maternal satisfaction of pediatric providers of children with selected chronic illness.Patients and Method: A cross sectional study, conducted in Babylon Gynecology and Pediatrics Teaching Hospital (wards and outpatient clinic), Al-Hilla, Iraq. From October 2011 to November 2012. Information was collected by interview with mothers of 110 children with one of four chronic illnesses (asthma, diabetes mellitus, cerebral palsy and congenital heart disease) to determine their response about pediatric providers whom they consulted in the last year, seen most frequently, and who were seen over the longest period of time. Rates of dissatisfaction with those providers are also reported .Result: The probability of reporting a high level of satisfaction (extreme satisfaction) was for subspecialist pediatric care providers than with specialist pediatrician, P- value <0.04, but mothers mentioned that specialist pediatrician providing better general health care, P-value <0.001,realy listening to their opinions, P-value <0.002,and ability to answer questions about condition, P-value <0.02.Conclusions: Achievement of Mothers-pediatrician communication ensures best maternal satisfaction
The Relationship among Interlukin-10 ,Interlukin-6 with anti-cyclic citrullinated peptide antibody, C-reactive protein ,Rheumatoid factor in patients with Rheumatoid Arthritis
Authors: Abbas Hasan Ahmed
Published: January 2024

Rheumatoid arthritis (RA), the most severe disease affect the joint and also the most common systemic autoimmune disease, affecting approximately 1% of the adult population .We investigate the serum levels of IL-10 and IL-6 in patients with Rheumatoid arthritis. About forty patients with Rheumatoid arthritis (30 female and 10 male) with ages ranged between (20-70) years were taken from (Al-Hussein Medical City/Kerbala).Control group consisted of 20 healthy people were free from signs and symptoms of arthritis were matched in age and gender with patients, and had no history for any arthritis problem .IL-10 (IL-10-EASIA Kit, DIAsource) (IL-6 ELISA kit ,immunotech),(Anti CC-P ELISA kit ,Medizym/Germany ) ,(RF ELISA Kit Euroimmun/Germany) were measured using the enzyme-linked immunosorbent assay (ELISA) method and CRP Vital kit using quantitative turbidimetry method . t-test , ANOVA and Pearson correlation were used to analyze results by using SPSS version 22. P-value â‰¤ 0.05 was considered significant. IL10,IL6,Anti-CCP,CRP and RF were increased significantly (p< 0.05) in patients compared with control group, So increasing of IL10,IL6,Anti-CCP,CRP and RF values at mild stage (41.4Â±1.3),sever stage(54.8Â±0.8),sever stage(952Â±114), server stage(49.3Â±1),sever stage (181.3Â±11) respectively increased significantly value (p< 0.05) among the stages, The results revealed no significant value (p>0.05) among the age groups and according the gender groups, While there were highly significant correlation (p< 0.05) found among studded parameters .
The Relationship Between The Type 1 Diabetes And Celiac Disease: A Study Based On Anti Tissue Transglutaminase Antibodies And Anti-Glidine Antibodies Screening
Authors: A.AL-Hilali Hammadi , I. Mohammad Bassim , H. Khlebos Ali
Published: January 2024

Background: The present investigation aims to study the prevalence rate and clinical characteristics of celiac disease(CD)among Iraqi children with type1 diabetes mellitus using a combination of the most sensitive and specific screening serologic tests anti-tissue transglutaminase antibodies IgA,IgG(tTG)and anti-gliaden antibodies IgA,IgG(AGA) and to determine the lower cut-off value of anti-tTG and anti-AGA level that best predicts celiac disease in patient with type1 diabetes. Materials: Two patient groups have investigated (each to NO =30) in this study one with celiac disease and the other with type1 diabetes mellitus compared to third group of apparently healthy control group of 20 individuals. patient with positive anti-tTG titer and AGA titer (>18 U/ml) and patient with equivocal of anti-tTG and AGA titers(12â€“18 U/ml) and negative titers (<18 U/ml ) Results: The median calculation of Anti-gliadin IgA (U\ml) were ;1.6 ,6.15 and 27.4 among healthy group ,type1 diabetes mellitus, and celiac disease patient respectively. An interesting ROC values (AUC 0.949-1.000) for this auto-antibodies as a perfect test in this aspect. In the same context, the IgG ,class of this auto-antibody occurred in median concentration of 3.05, 5.7 , and 21.85 among the three groups ,respectively. It significantly differed among this group and as compared to each other's. For anti-tissue transglutamenase assays ,Both IgA and IgG were provided with significant differentiation tools when compared among the three studied groups both classes provided had high ROC (0.947- 1.000). Conclusion: From the result of this study, we concluded the overlapping auto-antibodies profile celiac disease and type1 diabetes mellitus.
Nd YAG LASER treatment for leukemic childhood blindness
Authors: Twafeeq Hilbous Mustafa
Published: January 2024

Aim of the study: is to study the rule of laser therapy by the (Nd-YAG) laser in the treatment of premacular haemorrhage in leukemic childrenMethod:It is a prospective study was taken in department of ophthalmology in al hilla teaching hospital .eleven eyes of eight children 3 girls and 5 boys age between 7-14 years old and they have premacular haemorrhage due to leukaemia .family permission was taken after explaining to the family the surgical procedure .topical anesthesia by lidocaine and pupil dilatation by mydriacil and the Goldman 3 mirror and Nd â€“YAG laser was delivered the power was 5 mj and increased by 1 mj when the desired response not gained and the power should not exceed 11mj and the number of shoots should not exceed 10 per section and the pt was followed after 1 week then after 6 weeks then after 3 months.Results:Drainage of the premacular hemorrhage into the vitreous happened in 9 eyes of 11eyes after the end of the follow up period which is 3 months The mean force used was 6.5 mj.After 1 week the improvement in VA was between hand movement and 6/6 and the mean was 6/18After 6 weeks the improvement in VA was between hand movement and 6/6 and the mean was 6/9There is no big difference in improvement in VA after 3 months to that after 6 weeksOne pt who had lymphoblastic leukemia had clotted hemorrhage that could not be drained into the vitreousAnd another pt who had myeloid leukemia had re-hemorrhage as a result of deterioration in his illnessConclusion:From the result of this study we can see that the use of Nd-YAG laser in the treatment of leukemic pts with premacular hemorrhage is safe and effective in comparing with parsplana vitrectomy under GA specially when we use good selection of pt especially those with bilateral premacular hemorrhage and we can consider the Nd-YAG laser as a routine therapy for the leukemic children with premacular hemorrhage.
Assessment of Myocardial Infarction Risk among Patients in Babylon City
Authors: Abbas Dawood Hussam
Published: January 2024

IntroductionThe idea of assessment of myocardial infarction risk factors among patients comes while Cardiovascular disease is the leading cause of death in Iraq.1 While myocardial infarction has been described to have an epidemic like spread all over the world with special emphasis on countries experiencing the transition to lifestyle, it is important to evaluate the life style and behaviors of those patients after the onset of myocardial infarction.2ObjectivesPresented study aimed to assess and find out the frequency and significance of known risk factors in our patient population in Babylon City of myocardial infarction patients.Materials and MethodsDescriptive design for risk factors of myocardial infarction among patients life in Babylon City were assessed.150 patients were a purposive sample from Babylon community to participate in this study (108 Male, 42 Female). Those are patients with myocardial infarction included from two main hospitals an Al-Hilla hospital n=100, Marchan hospital n=50, CCU unit. Microsoft Excel and SPSS software were used to analyze the data collected and to obtain results.ResultsMost of sample study participants were more than 40 years old. The majorities of participants live in Babylon city, finished their secondary level of education and illiteracy patients level. The results according to the gender were 64.81%of males and 66.67% of females of the study sample were diabetic, and 80.56% of males and 71.42% of female of the study sample were hypertensive, while 59.26% of males and 35.71% of females of the study sample electives had cardiac diseases. All participants were surveyed for diet, physical activity, smoking, knowledge, attitude, practice, and drugs compliance. Most of patients have no physical activity (86% of males and 98% of females), no control diet (65% of males and 48% of females), while percent of smoking patients were high according to their health situation (60% of males and 21% of females).ConclusionThe political and economical situations of Patients in Babylon city, and lack of health information among patients and their families, were the major reason of the lifestyle impairment. Patients who survived acute myocardial infarction need more attention and rehabilitation programs, this needs the efforts of primary health care centers, Nurses and cardiologists.
Outcome of surgical sperm retrieval and ICSI in Iraqi azoospermic patients
Authors: G. Alessawi Saadeldeen
Published: January 2024

Although ICSI technique represents the cornerstone in the management of infertility worldwide, this technique was only recently introduced to our country and this might be the first prospective study of its kind that done in Iraq which tries to evaluate the outcome of surgical sperm retrieval in azoospermic Iraqi patients using different methods of surgical sperm retrieval technique and to evaluate the pregnancy rate for those patients who tried ICSI.Patients and methods:- This was a single center prospective study, which was performed at the reproductive and ICSI center, department of urology at AL-SADER MEDICAL CITY. The time of enrollment was from sixteenth of February to sixteenth of December 2011. A total of 146 azoospermic patients have been included in this study. Surgical methods which were used for sperm retrieval included PESA, TESA, simple TESE, open surgical epididymal sperm aspiration, open multiple TESE and Micro surgical TESE.Results:- The aim of our treatment is to obtain and freeze sperm sufficient for at least two ICSI cycles. The total number of patients who had met the above criteria after surgical sperm retrieval (SSR) was 92 patients out of 146 patients included in the study. The overall success rate was 63%, this including 100% success rate in obstructive azoospermia and 45% success in NOA. For those patient who try ICSI at time of this study the fertilization rate was 85% , embryo transfer was done in 75% , and the pregnancy rate was 23%.Conclusion:-Although the combination of surgical sperm retrieval (SSR) and ICSI may be the sole treatment available for male factor infertility with uncorrectable azoospermia, the overall success rate is limited particularly in NOA and ongoing pregnancies are obtained in <25% of ICSI cycles. However every azoospermic patients should offer such option of treatment and for those patients who had succeed sperm retrieval, multiple ICSI cycle trials may increase the chance of pregnancy without the need for repeated surgery. Open surgical methods of SSR, has been shown to increase the options available to the embryologist to use , select and cryopreserved sperms, however it will increase the surgical trauma to the testicles and increase the tissue extracted , the effects of these factors on the future testicular function needs to be investigated by further studies.
Detection of Mycoplasma hominis and Ureaplasma Urealyticum in urethritis from sexual active men by Real-time PCR
Authors: A. Muhammid Haider , S. Naher Habeeb , H. AL-Hamadani Adnan
Published: January 2024

Background: Mycoplasma spp and Ureaplasma spp are unique microbes in they lack a cell wall and cause genitourinary tract infections ,these organisms are considered an intracellular parasites and difficult to cultivate in routine media due to the complexity of their nutritional requirements so , the molecular detection and identify these microorganisms by Real-Time PCR due to cost, time, reliability, specificity, and sensitivity.Aim of study : To detect and differentiate Mycoplasma hominis and Ureaplasma urealyticum isolates from patients with urethritis by Real-Time PCR.Methods: Ureathral swabs collected from 60 sexual active men from December 2012 to May 2013 who attending to AL- Diwanyia Teaching Hospital were tested by using DUPLICÎ± RealTime PCR kit for the presence the of genital mycoplasmas (Mycoplasma hominis based on amplification of 16SrRNA gene and Ureaplsma uralyticum based on amplification of urease gene ) , the age of patients study with urethritis were (18-41) year old. . Results: Out of 60 Urethral samples there 28 were positive samples as 3 (10.7%) , 17 (60.7%) and 5 (17.8%) for M.hominis (as a single pathogen) ,U.urealyticum (as a single pathogen) an both of genital mycoplasma respectively the age group (30-35) years old was more significant (P<0.05) than other group ages.Conclusion :Real-PCR shows a rapid and high accuracy in detection and differentiation of M. hominis and U. urealyticum from clinical samples.
The Outcome of Varicocelectomy on Sperm Parameters in Subfertile Men with Clinical Varicoceles Who Have Asthenozoospermia and or Teratozoospermia with Normal Sperm Count
Authors: Ali Ghadhban Mohammed , Abdulameer Alwan Ahmed
Published: January 2024

Design Of Study: prospective study.Duration: From 2014 to 2015Setting: Department of Urology, AL-Diwaniya teaching Hospital, Infertility clinic.Patients & Methods: Over a period of one year hundred (100) patients with varicocele associated with male infertility over a 3-years period were included in this study. Pre- and postvaricocelectomy seminal fluid parameters evaluation according to the World Health Organization (WHO) criteria was performed at 6-month intervals.General anesthesia was given to all patients.Results:One hundred patients met the criteria their age range from 25 to 45 years with a mean age of 32Â± 3 years. The mean duration of infertility was 3years (range: 1.5â€“6).). Only the sperm motility of patients with normospermia showed a significant improvement postoperativelyConclusion:No significant improvement in sperm morphology may be obtained inpatients with clinical varicocele and preoperative normospermia.
The Impact Of Maternal Diabetes On Newborns Admitted To Neonatal Care Unit Of Maternity And Children Teaching Hospital in Al-Diwaniya city
Authors: Saleh Saheb Hulal , Hameed Muaid , Jasim Al-Fatlawi Salam
Published: January 2024

Diabetes has long been associated with increased perinatal morbidity and mortality It's one of the commonest and important metabolic disorder that affect the health of both mother and infant .Patient and methodsTotal number of patient involved were one hundred eighty four , Ninety-nine of them were infants of diabetic mother , they were admitted to the NCU of AL-Diwaniya teaching hospital from the 1st of October 2013 to the end of march 2014. Eight-five neonates were also enrolled in this study as control (infants of non-diabetic mothers)ObjectiveTo determine the morbidities and mortality among infants of diabetic mother and to compare it to that of control.ResultThere is higher morbidity and mortality amongst IDM . Hypoglycemia was the commonest morbidity recorded (31.3%) followed by hyper bilirubinemia (13.3%) and respiratory distress (12.1%). More prolonged hospitalization had been seen amongst IDM.ConclusionThere is higher frequency of morbidity and mortality amongst IDM , hence ascertain a good glycemic control to diabetic mother and providing optimal neonatal care is valuable to decrease these complications.