bluuebunny/crossref_metadata_2025 huggingface dataset:
People's Health Surveillance in the Construction of Coexistence with the Semi-Arid in Times of Pandemic COVID-19
Authors: Knierim Gislei Siqueira , Pereira Gáudia Maria Costa Leite , Andrade Luciano Pires de , Gervais Ana Maria Dubeux
Published: September 2022

The training-action process called "The Cycle of Meetings: Healthy and Sustainable Territories in the Brazilian Semi-Arid - Popular Health Surveillance in Times of Pandemic", was characterized as a training space organized by the Articulation of the Brazilian Semi-Arid (ASA) and the Health Environment Work Program (PSAT) of Fiocruz - Brasília in the period from August to September 2020 where it sought to encourage dialogue, the construction of knowledge, the strengthening of community relations with the Unified Health System (SUS) and build strategies to confront the Covid-19 health crisis in the territories of the Semi-Arid. The Cycles were organized in five virtual meetings and territorial actions between meetings. They were oriented towards the construction of new models of understanding and action in the face of the Covid-19 pandemic, in order to discuss how the adoption of theoretical and practical approaches can enable the action of the organizations that make up ASA in the territories to strengthen agroecological transition systems, appropriate technologies for access to water and food security for families in the Sertão. It resulted in the construction of guiding principles for health practices for the resumption of the activities of ASA organizations in the territories in times of pandemics.
Gender Essentialisms and the Abject: Understanding Transgender Identity in Jackie Kay's Trumpet
Authors: Scott Laura
Published: September 2022

This article focuses on the tensions between essentialist and fluid conceptions of gender identity in Jackie Kay's Trumpet (1998). Joss Moody, a Black Scottish jazz trumpeter who is posthumously revealed to have been biologically female, is constructed largely through external characterisations. The most significant of these narratives are his wife Millie's and his son Colman's. I first illustrate the importance of performativity in understanding gender identity through the work of Judith Butler. This provides context for my discussion of Millie and Joss, focused on the relationship between the pellicular and the sartorial. The narrative focus on skin and the body versus clothing serves to illustrate Millie's understanding of gender as fluid and performative. In the second section of the essay, I outline the abject and address Colman's expulsion of that which threatens his sense of self. Positing that his perception of Joss as a representative of the maternal that must be expelled in order to enter the Symbolic and constitute a self, his understanding of gender on binary terms is the key element in his internal struggle. Embarking on a journey to learn about his father's life, Colman's refocusing on personal, lived experience allows his views to align with Millie's by the end of the novel. Thereby, Kay illustrates the tension between binary and nuanced understandings of gender in Trumpet, and the method by which this can be overcome: an inclusive understanding that undermines notions of a hegemonic masculinity from which non-conformants can be excluded based on bodily attributes.
Rethinking Algerian Visibility and Invisibility in Ali au Pays des Merveilles
Authors: Li Chengxi
Published: September 2022

This article examines Djouhra Abouda and Alain Bonnamy’s experimental documentary Ali au pays des merveilles (1975) and discusses how the filmmakers expose Algerian workers’ living conditions in the 1970s France, a promised land where racism and exclusion persist. This study analyses the visibility and invisibility of the Algerian labour by first discussing the exclusion of Algerian migrants on the basis of their racial identity and their social status, in light of thinking related to French republican identification. The author then examines the interrelations between the Algerian labour and the commodities produced by their labour, as well as the glamorous spectacle associated with the commodities. Finally, the article reflects on the reflexive archaeology of the image that questions the power and limits of archives, interrogating the entanglements of French colonial history in Algeria. The article argues that Abouda and Bonnamy’s stylistic devices are in line with those of the Third Cinema, providing an alternative that allows post-colonial sensibilities to challenge the official discourse and the self-claiming “universal” but indeed Eurocentric aesthetics.
Asserting and Accompanying the Excluded Self: The Function of the Recorded Voice in Samuel Beckett’s Krapp’s Last Tape and Rockaby
Authors: Schiza Maria
Published: September 2022

In Samuel Beckett’s plays Krapp’s Last Tape (1958) and Rockaby (1980), there is one character on stage, alone, accompanied only by the presence of his/her own recorded voice, played back to himself/herself. The recorded voice of each of the characters becomes a way of proving to themselves that they have existed before the present moment, and, at the same time, it becomes a companion, disrupting silence and aloneness. Finally, it is the recorded voice that allows the characters to fully exist while excluded from the company and comfort of others, as they fulfill their own needs through  their own voice.
To Exclude or Not to Exclude? The Question of Nationality as a Category in Queer Studies
Authors: Singh Aakanksha
Published: September 2022

This paper will try to look at some of the problems of categorisation through the prism of my own reservations and concerns when researching the novel Babyji (2005) by Abha Dawesar. The paper will examine whether categories and classifications are capable of including all the exclusions that they purport to remedy. In particular, this paper will examine the usefulness of the term ‘queer’ and the category of the nationality ‘Indian’, as well as the simultaneous problems that arise from using the category of nationality in conjunction with queerness. Moreover, it does not implicitly entail that the more categories sprout in the world, the more inclusive the world will be toward queer individuals. The paper will therefore interrogate if there is a way out at all from this conundrum of labelling and binding oneself to these categories. This interrogation is done by challenging the idea that it is easier to think of Dawesar’s novel from a monolithic perspective of nationality, while the novel’s other facets are conveniently allowed to fade by critics and researchers. To think of Babyji as more than just a nationalistic novel, the paper applies Gayatri Spivak’s concept of “foreclosure” (“The Intervention Interview” 125). Spivak, borrowing the term from Lacanian psychoanalysis, differentiates foreclosure from exclusion and conceptualises the former “to mean the interested denial of something”. By using this term, the paper thus explores other interpretations of Babyji, concluding that thinking beyond categories (despite them being a necessary evil) is quite possible.
Оптический пеленгатор для автономной посадки космического зонда на малые тела Солнечной системы
Authors: Лобанов А.А. , Можаров Г.А. , Филонов А.С.
Published: September 2022

Предлагается оригинальная конструкция оптического четырехканального пеленгатора
с полярной корреляцией. Пеленгатор, входящий в состав многофункционального
бортового комплекса космического летательного аппарата, способен значительно
повысить точность наведения при посадке на малые тела Солнечной системы,
осуществляемую в автономном режиме. Модель пеленгатора создана в тонких компонентах на основе математического моделирования и законов геометрической оптики.
Greater Social Mobility of Tribal Women in Rural Jharkhand: A Case Study Business Women and Women Entrepreneurs, A Pilot Study from Jharkhand
Authors: Munjal Khyati , Hans Dr. Arvind , Shankar Prem
Published: September 2022

Abstract: Entrepreneurship is the ability and readiness to develop, organize and run a business enterprise, along with any of its uncertainties to make a profit. Despite men and women gliding through the same entrepreneurial process, women face distinct dimensions and intense challenges in realizing their potential. When women or groups of women embark on initiating, organizing, and managing their enterprise, they are termed as women entrepreneurs. There is indeed a difference between an entrepreneur and a businesswoman. After all, both are about running a business and leading teams. It is also true that an entrepreneur can become a businesswoman. businesswomen walk on a defined path, but an entrepreneur believes in making his own path, which becomes a guideline for other businesswomen.
Glomerulonefritis rápidamente progresiva secundaria a vasculitis pauciinmune, entidad poco frecuente: caso clínico y revisión de la literatura
Authors: Giraldo Ocampo Christian Camilo , Jimenez  Bejarano Maria Fernanda , Serna Flórez Jhon
Published: September 2022

Introducción: las vasculitis asociadas a anticuerpos anticitoplasma de neutrófilos (ANCA) son un grupo heterogéneo de patologías, caracterizadas por la inflamación y la destrucción de vasos sanguíneos de pequeño y mediano calibre, asociados a la presencia de ANCA circulantes. Se presentan con una amplia variedad de signos y síntomas y, si no se tratan, conllevan a una alta morbimortalidad. Estos constituyen una causa poco frecuente de glomerulonefritis rápidamente progresiva y lesión renal aguda con necesidad de soporte renal, por lo que se requiere un alto índice de sospecha en el abordaje inicial.
Objetivo:  con el presente artículo se busca sensibilizar al personal médico sobre la necesidad de una búsqueda activa de vasculitis como causa de glomerulonefritis y el impacto del diagnóstico y tratamiento tempranos en la condición clínica del paciente.
Presentación del caso: paciente masculino de 65 años atendido en un centro hospitalario de referencia en la ciudad de Pereira, Risaralda, quien debuta con glomerulonefritis rápidamente progresiva secundaria a poliangeítis microscópica en su posoperatorio de prostatectomía, y que progresa a lesión renal aguda con necesidad de inicio de soporte renal de tipo hemodiálisis intermitente; posterior a realizar biopsia renal y perfil de autoinmunidad, se confirma el diagnóstico de vasculitis tipo poliangeítis microscópica, se inicia manejo específico inmunosupresor, con lo que se logra la remisión de la enfermedad y con ello una mejoría en la función renal que permite suspender la terapia de reemplazo renal.
Actualmente el paciente permanece asintomático, con remisión de su enfermedad con manejo inmunosupresor, asistiendo a controles ambulatorios con Nefrología sin mención de complicaciones secundarias a terapia farmacológica.
Discusión y conclusión: En las vasculitis asociadas a los anticuerpos anticitoplasma de neutrófilos (ANCA), el diagnóstico oportuno y el establecimiento de una terapia inmunomoduladora adecuada son el pilar fundamental en el abordaje de esta entidad. Un diagnóstico tardío está directamente relacionado con un pobre pronóstico a corto plazo. El diagnóstico oportuno requiere de un índice de sospecha apropiado.
Quality of Life and Associated Risk Factors in Hemodialysis: Perspective from a Center in the Dominican Republic
Authors: Jimenez Ramirez Rigoberto , Lopez Gonzalez Franz Erich , Rivera Martínez Arlenys Rachel , Rodríguez Liriano Carlin Grisellis , Lara Pichardo Julessy Nathalie , Acosta Díaz Yandra
Published: September 2022

Background: Chronic kidney disease has an overall prevalence of 10?%. It can progress to a condition called end-stage renal disease. Therapies such as hemodialysis are necessary at this stage. Our study aims to measure the quality of life of patients on hemodialysis.
Methods: We conducted an observational, cross-sectional study with 81 patients. Data was collected using a survey that included sociodemographic variables, the Center for Epidemiological Studies Depression Screening Index (CES-D), and the Kidney Disease Quality of Life (KDQOL-SF36). Data were analyzed using the software Epi Info™ 7.2, t-test, ANOVA, and correlation coefficient.
Results: The severity of symptoms is more significant in the female sex than in males (65.7117 vs. 74.2874). All of the components of the KDQOL-SF36 showed a negative correlation with the CES-D. Household income had a mild positive correlation with the scale (r = 0.2608, p = 0.0229). Physical activity was shown to be associated with the physical component of the scale (41.6346 vs. 35.7365, p = 0.0412). Patients with partners were associated with higher quality of life scores than single patients (53.6585 vs. 42.6783, p = 0.0348).
Conclusion: This is the first study conducted in the Dominican Republic to analyze the variables affecting the quality of life in patients in hemodialysis units. The severity of the symptoms increased in female patients, and patients without a partner are associated with worse quality of life scores.
EL BUQUE-FACTORÍA GOBERNADOR BORIES Y LA CAZA DE BALLENAS DESDE PUNTA ARENAS (1906-1914
Authors: Quiroz Daniel
Published: September 2022

Gobernador Bories fue el primer buque-factoría que procesó ballenas bajo bandera chilena en aguas de la Antártica. Construido en Inglaterra en 1882, fue convertido en buque-factoría en Noruega en 1906 para la Sociedad Ballenera de Magallanes. Realizó, entre 1906 y 1914, ocho expediciones a las Shetlands del Sur, operando durante la temporada de verano principalmente en bahía Balleneros, isla Decepción. Otra de sus funciones era el transporte del aceite producido por la compañía a Europa, que se realizaba durante el invierno de cada año. En 1914 fue hundido por la Royal Navy en Scapa Flow para usarlo como buque de bloqueo en la Primera Guerra Mundial. En este artículo, considerando la naturaleza fragmentaria y dispersa de la información disponible en periódicos de Reino Unido, Países Bajos, Alemania, Noruega y Chile, reconstruimos la biografía del buque-factoría, sobre todo los servicios prestados a la Sociedad Ballenera de Magallanes
Usefulness of ultrasonography in diagnosis of intestinal obstruction by a water bead
Authors: Kim Yoon Soo , Jung Hyeon Joon , Choi Seo Yeol , Hong Kyung Sik , Seo Ju-Hee , Kim Jeong Rye , Park Youn Joon , Lee Kunsong
Published: September 2022

Water beads are dangerous foreign bodies causing intestinal obstruction in young children because the beads absorb water and are radiolucent. Although the features lead to progressive intestinal obstruction, it is difficult to diagnose ingestion of the beads by imaging studies. For the diagnosis, ultrasonography is safe, fast, and accurate. The imaging modality can show intestinal water beads as spherical, anechoic, smoothly demarcated cysts. This characteristic finding may be more useful in rapid and accurate diagnosis than computed tomography scan. We report a case of an 8-month-old boy who obtained a timely sonographic diagnosis of water bead-induced small bowel obstruction in the emergency department.
FLAMMABILITY BEHAVIOURS OF KNITTED FABRICS CONTAINING PLA, COTTON, LYOCELL, CHITOSAN FIBERS
Authors: ALAYBEYOGLU Emel , DURAN Kerim , KÖRLÜ Ayşegül
Published: September 2022

In recent years, studies have focused on the development of fire retardant products that are produced without the use of flame retardants with toxic effects and do not have harmful effects on humans and the environment. In this work, it has been compared the flame retardant properties of some biodegradable fibers obtained from different sources. It is important to investigate the performance of textile surfaces obtained from renewable fibers for flame retardant products and to improve their usage possibilities. The fire retardancy properties of knitted fabrics containing PLA, cotton, lyocell, and chitosan fibers were studied by analyzing the LOI values and burning behaviors. Single jersey knitted fabrics composed of 100% PLA, 100% Lyocell, 95% PLA 5% Chitosan, 95% Cotton 5% Chitosan, 95% Lyocell 5%Chitosan, 80%PLA 15%Cotton 5%Chitosan, 80%PLA 15%Lyocell 5%Chitosan were produced. The flame speed of each material was determined and differences in the flammability behaviors of the fabrics were identified. The lowest flammability occurred for the fabric 95% PLA 5% Chitosan. The highest flammability was for 100% Lyocell knitted fabric.
A Method of MVDR Spatial Spectrum Estimation Based on Richardson Lucy
Authors: Qiu Lan , Xie Yuchen
Published: September 2022

For the problem of influence of background level on estimating target
spatial azimuth distribution value, a method of MVDR spatial spectrum
estimation based on Richardson-Lucy is proposed. The output results of
MVDR spatial spectrum estimation method were deconvolution with point
scattering function and Richardson-Lucy iterative method of image
restoration, and the background level and its influence on estimating
target spatial azimuth distribution value was reduced. The results of
measured data show that, this method is a post-processing method,
inherits the high resolution performance of MVDR spatial spectrum
estimation method, has more sharp peak value, when signal to noise ratio
is lower, has better performance of estimating target spatial azimuth
distribution value.
New solutions for investigation of nonlinear fractional differential equations
Authors: Ganji Davood Domeiri , Chari Fateme Nadalinia , Pasha Pooya
Published: September 2022

In this essay, the nonlinear fractional integral equation is studied.
Akbari-Ganji’s Method (AGM), Homotopy Perturbation Method (HPM) and
Vibrational Iteration Method (VIM) are applied to obtain its solution.
We present a new strategy for finding the approximate solutions to
Fractional differential equations. We experience Fractional differential
equations, which are broadly utilized in fluids. In this article, we
have used analytical methods to check the correctness of the answers.
Ordinary equations and fractional differential equations are related to
entropy and wavelets, and so on. A few examples are employed to appear
accurate and simple to implement and demonstrate the method. The
solutions are clarified in convergent series. Some well-known models for
anticipating the oscillation behavior of the action in a vibrating
system are presented, then with the help of fractional calculus which
could exceptionally powerful tool in mathematics and modeling of complex
systems, a model for the same system is proposed. Compare the models and
finally show that the proposed fractional model not only includes
non-fractional models but also predicts the behavior of the system more
comprehensively.
Non-oscillatory Solutions of Higher-order Forced Nabla Fractional Difference Equations with Positive and Negative Terms
Authors: Santra Shyam , Grace Said , Jonnalagadda Jagan Mohan , Alzabut Jehad
Published: September 2022

In this work, we obtain new sufficient conditions for the
non-oscillatory solutions of forced nabla fractional difference
equations with positive and negative terms. The results are developed in
sense of Caputo nabla fractional difference operator and by the help of
Young’s inequality as well as an equivalent representation in form of a
Volterra-type summation equation. The results improve some existing
results in the literature. Further, two examples are presented to
support and illustrate the applicability of the deduced results.
Utility of FDG PET/CT in Patient with Synchronous Breast and Colon Cancer
Authors: Su I Lin , Chen Yen Kung
Published: September 2022

A 60-year-old woman with breast invasive ductal carcinoma underwent FDG
PET/CT scan for cancer staging. A synchronous colon cancer was detected
incidentally. After resection of colon cancer, she received CCRT for
breast cancer. Marked therapeutic response was found throughout the
follow-up period. Also, there was no evidence of cancer recurrence.
Aquagenic Palmar Wrinkling: Case Report and Literature Review
Authors: Stroia Alexandra , Schleicher Stephen
Published: September 2022

Aquagenic Palmar Wrinkling is a rare, transient disorder induced by
brief contact with water. It has been noted in cystic fibrosis patients.
We describe a unique case of a 17-year-old male with no history of
cystic fibrosis, who presented with shriveled palms and multiple whitish
papules following brief water immersion.
Effects of Irrigation at Different Times During the Freeze--thaw Period on Soil Evaporation
Authors: Chen Junfeng , Pan Daquan , Xue Jing , Cui Lihong , Zheng Xiuqing , Du Qi
Published: September 2022

Controlling soil evaporation during the seasonal freeze–thaw period has
important practical significance for alleviating the water shortage in
northern China. To investigate the influence of different irrigation
times on soil evaporation during the freeze–thaw period, a series of
field soil evaporation experiments of bare soil and sand mulch
treatments with six different irrigation times were conducted. Soil
evaporation characteristics during the three freeze–thaw stage were
determined, and the major factors influencing soil evaporation were
analyzed using the Random Forest model. The results showed that the
cumulative soil evaporation of bare soil irrigated at different times
during the freeze–thaw period was 43.1–50.37 mm, which was
33.8%–56.4% higher than that of bare soil without irrigation, and
soil evaporation decreased by 10.4%–39.2% after the addition of
mulched sand. Shortly after irrigation, surface sand mulch exhibited a
weak inhibitory effect on soil evaporation in the stable freezing stage
and later thawing stage. Sand mulch with irrigation in the early
unstable freezing stage had the most positive effect on soil moisture
preservation, with 80.95% of the irrigation water stored in the soil
during the freeze–thaw period. Simultaneously, the surface soil
moisture content was the major factor affecting evaporation in irrigated
treatments in the unstable freezing stage and stable freezing stage;
surface soil temperature, surface soil moisture content, and average air
temperature were the major factors affecting soil evaporation, and
surface soil moisture content had the greatest contribution to soil
evaporation in the thawing stage. The results suggest that the addition
of irrigation water early in the winter along with sand mulch in
agricultural fields may be a beneficial practice to reduce water stress
in arid and semi-arid areas.
Evaluation of different concentrations of Sea kelp and K-Humate in coal tailings rehabilitation South Africa
Authors: Daniell Angelique , Ainslie Ruan , Koch Jaco , Deventer Pieter van
Published: September 2022

Sea kelp and potassium Humate are two amendments commonly used in the
agronomy and crop science industries to improve germination and root
development. This study evaluated different concentrations of Sea kelp
and potassium Humate in rehabilitating coal tailings. The aim was to
evaluate the growth potential of Cynodon dactylon and to set
norms for coal tailings about Sea kelp and potassium Humate .
Four different concentrations of each ameliorant were applied to the
coal tailings, where the pH, of the medium was measured and for the
grass specie, germination, survivability, and growth performance were
measured. First, it was deduced that these amendments positively
affected the establishment and survivability of Cynodon dactylon
on the coal tailings. Secondly, it was found that the application of Sea
kelp and K-Humate had a buffering effect on the reacidification of coal
tailings. The highest concentration of Sea kelp and the agricultural
norm for potassium Humate showed the highest buffering capacity.
Megaoesophagus Presenting as Stridor
Authors: Drever Sara , Thirumal Vanushia , Cooper Fergus , McAteer Dympna
Published: September 2022

Acute airway obstruction is a rare presentation of megaoesophagus.
Megaoesophagus is commonly caused by achalasia; however, we present a
case of megaoesophagus caused by idiopathic dysmotility disorder.
Decompression with a wide bore nasogastric tube avoided a scenario of
difficult intubation or emergency front of neck access
An unusual case of lip hyperplasia and ulceration
Authors: Cunha Maria da , MD Tiago Marques
Published: September 2022

Paracoccidiomycosis is a systemic fungal infection present in certain
regions of South America; although it predominantly affects the lungs,
it may cause oral disease. This case was characterized by upper lip
swelling and ulceration, in which the correct diagnosis was initially
delayed due to lack of awareness of this disease.
CRYOTHERAPY FOR TREATMENT OF SPOROTRICHOSIS: CASES OF COMPLETE CURE WITH PHYSICAL MODALITY ONLY
Authors: Pudasaini Prajwal , Paudel Sushil , G.C Sagar , Adhikari Sadiksha , Pudasaini Prashanta
Published: September 2022

Sporotrichosis is a fungal infection caused by various sporothrix
species. Given the systemic side-effects that underly the use of
antifungals for prolonged duration, treatment should be sought towards
isolated physical modality only which are devoid of systemic side
effects. we report two cases treated cryotherapy with complete cure.
Classification of Cassava Leaf Diseases using Deep Gaussian Transfer Learning Model
Authors: Emmanuel Ahishakiye , Mwangi Ronald , Murithi Petronilla , Fredrick Kanobe , Danison Taremwa
Published: September 2022

In Sub-Saharan Africa, Professionals visually analyse the plants by
looking for disease markers on the leaves to diagnose cassava
infections, however, this method is extremely subjective. Automating the
identification and classification of crop diseases may improve the
accuracy of professional disease diagnosis and enable farmers in remote
areas to monitor their crops without the assistance of experts.
Algorithms for machine learning have been used in the early detection
and classification of crop diseases. Motivated by the current
developments in the field of Gaussian Processes, this study proposes to
integrate the transfer learning approach with a deep Gaussian
convolutional neural network model (DGCNN) for the detection and
classification of cassava diseases. During this study, we used MobileNet
V2 and VGG16 pre-trained transfer learning models and a hybrid kernel.
Experiments with MobileNet V2 and a hybrid kernel revealed an accuracy
of 90.11%. Also, experiments with VGG16 and a hybrid kernel revealed an
accuracy of 88.63%. The major limitation of this study was computing
resources since we used an ordinary computer in all our experiments. In
our future work, we will experiment with the three kernel functions used
in this study with kernel algorithms such as support vector machines and
compare the results with those obtained during this study.
In-silico and in-vitro study reveals Ziprasidone as a potential aromatase inhibitor against breast carcinoma
Authors: sahu ankita , Ahmad Shaban , Imtiyaz Khalid , Islam Mojahidul , Raza Khalid , Easwaran Murugesh , Rizvi Moshahid , Verma Saurabh
Published: September 2022

Background and Purpose: The aromatase enzyme plays a fundamental role in
addressing the development of estrogen receptors and giving attention to
the therapy of reproductive disorders and cancer diseases. In clinical
use, the objectionable effects found in these target inhibitors are
indispensable in finding novel aromatase inhibitors with more selective,
less toxic, and more effective drug potency. Experimental Approach: The
research framework of this study is to identify a potent inhibitor for
the aromatase target by profiling molecular descriptors of the ligand
and finding a functional pocket of the target by docking and MD
simulations. For assessing cellular metabolic activities as an indicator
of cell viability and cytotoxicity, in-vitro studies were performed by
using colorimetric MTT assay. Cell morphology was assessed by
phase-contrast light microscope. Cell cycle distribution and apoptosis
were determined by flowcytometry and Annexin V-FITC/PI staining assay.
Key Results: This study reported herein the most promising compound
CHEMBL598797 (Ziprasidone) showed excellent activity potential to
inhibit aromatase in search of finding the novel compound based on
better drug design methods and experimental studies and could be
effective as the high potential drug candidate against aromatase enzyme.
Conclusion and Implications: We concluded that the compound ziprasidone
effectively blocks the cell cycle at the G1-S phase and induces cancer
cell death. Further in-vivo studies can be evaluated for developing this
compound as an anticancer agent. Overall, our outcomes based on the
in-silico and the high-quality experimental results may pave the way for
identifying effective drug candidates for better therapeutic interest
for breast cancer.
Slavonska
i petrinjska krajina (Varaždinski generalat) u 17. stoljeću
Authors: Štefanec Nataša
Published: September 2022

Članak prezentira funkcioniranje Slavonske i petrinjske krajine, također poznate kao Slavonska krajina ili Varaždinski generalat, u 17. stoljeću. Rekonstruira administrativnu i teritorijalnu organizaciju tog segmenta Vojne krajine, brojnost i funkciju rodova stajaće vojske te njihove plaće i zapovjednu strukturu. Uspoređuje stanje u 17. stoljeću sa situacijom u 16. stoljeću s ciljem ocrtavanja trendova u taktičkom i strateškom razvoju habsburških snaga na Vojnoj krajini (Militärgrenze).
Vjenčana kumstva na Mljetu u drugoj polovini 19. stoljeća
Authors: Gjurašić Marija , Kalajdžić Ahmet
Published: September 2022

Na temelju podataka iz matičnih knjiga vjenčanih župa Babino Polje (od 1870. do 1877.) i Maranovići (od 1870. do 1884.) i relevantne literature u radu se prikazuju godišnji i mjesečni intenzitet te ritam vjenčanja na Mljetu, praksa odabira svjedoka na vjenčanju (kolokvijalno zvanih vjenčani kumovi), njihov broj, spolna struktura i društveni status, višekratna kumstva te međusobno srodstvo mladenaca i vjenčanih kumova. Sporadično se razmatraju srodnički i udovički brakovi, „brakovi na probu” te mljetski svadbeni običaji i slično.
Some general Wilker-Huygens inequalities
Authors: Zhao Tie-Hong , Chu Yu-Ming
Published: September 2022

In this paper, we provide a systematic way to study on some general Wilker-Huygens type inequalities for the trigonometric and hyperbolic functions,
lemniscate and hyperbolic lemniscate functions, and their corresponding
inverse functions. Our results are some extensions and refinements of the
recently published results in [A. Mhanna, On a general Huygens-Wilker
inequality, Appl. Math. E.-Notes, 20 (2020), 79-81; MR4076436], and improve
many previous results involving Wilker-Huygens type inequalities.
SGLT2 Inhibition, Choline Metabolites, and Cardiometabolic Diseases: A Mediation Mendelian Randomization Study
Authors: Xu Min , Zheng Jie , Hou Tianzhichao , Lin Hong , Wang Tiange , Wang Shuangyuan , Luo Jielin , Zhao Zhiyun , Li Mian , Xu Yu , Ning Guang , Bi Yufang , Wang Weiqing
Published: September 2022

  

OBJECTIVE 

To investigate the causal role of choline metabolites mediating sodium-glucose co-transporter 2 (SGLT2) inhibition on coronary artery disease (CAD) and type 2 diabetes (T2D) using Mendelian randomization (MR). 

RESEARCH DESIGN AND METHODS 

A two-sample two-step MR was used to determine: 1) causal effects of SGLT2 inhibition on CAD and T2D; 2) causal effects of three choline metabolites, total choline, phosphatidylcholine and glycine on CAD and T2D; and 3) mediation effects of these metabolites. Genetic proxies for SGLT2 inhibition were identified as variants in the SLC5A2 gene that were associated with both levels of gene expression and hemoglobin A1c. Summary statistics for metabolites were from UK Biobank, CAD from CARDIoGRAMplusC4D consortium, and T2D from DIAGRAM and FinnGen study. 

RESULTS 

SGLT2 inhibition (per 1-SD, 6.75 mmol/mol [1.09%] lowering of HbA1c) was associated with lower risk of T2D and CAD (OR 0.25, 95% CI [0.12-0.54], and 0.51 [0.28-0.94], respectively), and positively with total choline (β 0.39, 95% CI [0.06-0.72]), phosphatidylcholine (β 0.40, 95% CI [0.13-0.67]) and glycine (β 0.34, 95% CI [0.05-0.63]). Total choline (OR 0.78, 95% CI [0.68-0.89]) and phosphatidylcholine (OR 0.81, 95% CI [0.72-0.91]) were associated with T2D, but not with CAD; while glycine was associated with CAD (OR 0.94, 95%CI [0.91-0.98]) but not with T2D. Mediation analysis showed evidence of indirect effect of SGLT2 inhibition on T2D through total choline (OR 0.91, 95% CI [0.83-0.99]) and phosphatidylcholine (OR 0.93, 95% CI [0.87, 0.99]) with a mediated proportion of 8% and 5% of the total effect, respectively; while through glycine (OR 0.98, [95% CI, 0.96-1.00] on CAD, with a mediated proportion of 2%. The results were well validated in at least one independent dataset.

CONCLUSIONS 

Our study identified the causal roles of SGLT2 inhibition on choline metabolites. SGLT2 inhibition may influence T2D and CAD through different choline metabolites.
Simulating and Modeling the Extensive Air Showers Development through the Estimating the Energy of some Created Particles
Authors: Fadhil Itab , Al-Rubaiee A. A.
Published: September 2022

Using the AIRES code and three hadronic interaction models, a simulation study of the energy of created particles due to the development of an extensive air shower was carried out (EPOS-LHC, QGSJET-II-04, and Sibyll2.3c). The main focus is put on the energy of the create particles as a function of depth for (12C,56Fe, p, and 28Si) primary particles with high primary energies (1017,1018,1019, and 1020) eV with two zenith angles  0° and 30°.  The New parameters were obtained by fitting the energy of created particles curves using Gaussian and linear functions for created particles, initiated by primary particles at the energy 1020 eV.  Good agreement was obtained by comparing the present results with results simulated by CORSIKA simulation for primary proton at the energy 1019 eV
Study of the Effect of the Geometry of the Inner Pole Arm of a Bipolar Lens
Authors: AL-Salih Rafa Y. J. , Jasim Hana Essa , Ismaeel Hafsa Yakdan
Published: September 2022

Several innovative designs were designed for magnetic lenses, a bipolar lens with innovative and different geometric shapes, where the outer Inner pole side of the iron shroud, which is symbolized by the symbol (L), was changed. 2,4,6 A/mm2) and after it was designed, the engineering parameters were studied in terms of magnetic properties, i.e., calculating the magnetic flux density with different current densities, and then studying the optical properties in terms of spherical aberration as well as chromatic aberration. Which made slight changes to the magnetic and optical properties of the bipolar lens and led to an improvement in the performance of the lens because the resolving power increased its amount when the change was made, as well as the aberration where both spherical aberration and chromatic aberration decreased.
Russian monarchists of the late 19th – early 20th centuries about Leo Tolstoy
Authors: Stogov Dmitrii I.
Published: September 2022

The issue of the attitude of various political forces of the early 20th century to Leo Tolstoy’s doctrines remains very relevant. On the one hand, it is due to the fact that the religious and philosophical ideas of the writer are still popular among liberal politicians and intelligentsia, contributing to the growth of oppositional, pacifist, and anti-clerical sentiments in a certain part of society. On the other hand, it is due to the “conservative turn” that is taking place today in the minds of the political elite and the majority of the population. In this context, historical themes related to the history of Russian conservatism are of increased interest. In this article an attempt was made to comprehensively analyze public addresses (speeches and sermons) and written sources (brochures, articles, books, diaries) of famous representatives of the right-wing monarchist (Black Hundred) movement of the late 19th – early 20th centuries, both priests of the Orthodox Church and the laity, which contain certain judgment about Leo Tolstoy’s activities and works as well as his religio-ethical and political views. The article concludes that almost all Russian conservatives positively assessed the writer’s literary talent, noting artistic merits of his literary works. At the same time, the article notes that the right-wingers severely criticized the religious views of Leo Tolstoy, considering them heretical and agreeing with the decision of the Most Holy Synod to unchurch the writer. The majority of the right-wingers considered the “spirit of pride” to be the main reason for Leo Tolstoy’s “spiritual decline.” The writer’s religious and ethical views were especially severely condemned by the Orthodox clergy. It is worth noting that some right-wingers found a rational grain in some aspects of Tolstoy’s worldview (vegetarianism, sobriety); at the same time, they specified that they condemned the writer’s “blasphemy.” The article emphasizes that despite the harsh criticism of Tolstoyism, right-wing political organizations (parties, unions) as well as unofficial right-wing structures (circles, salons) did not manage to develop a set of measures to counter Tolstoy’s doctrines, limiting themselves to verbal criticism of Tolstoyism.
Minister of War of the Russian Empire A.F. Roediger: Between service and politics
Authors: Egorov Andrey N.
Published: September 2022

The Russian Empire of the early 20th century saw gradual alienation of the supreme authority represented by the emperor and his inner circle from the bureaucracy and the generals who were their most important supporters, which contributed to the political crisis escalation. The article considers this issue on the example of certain aspects of the administrative and political activities of Alexander Roediger, General of Infantry, who served as Minister of War in 1905–09. The article shows his attempts to solve personnel problems in the army by removing unqualified personnel from the Higher Command, which caused discontent among the courtiers. The author analyzes A. Roediger’s political views, which can be described as moderately liberal. The Minister of War himself never went public about them, considering it unacceptable for an officer to engage in politics. However, due to his position, he could not completely distance himself from politics, especially during the revolutionary upheavals of 1905–07. Alexander Roediger belonged to those statesmen of Russia who sought to carry out serious reforms along the lines of constitution through a constructive dialogue with the legislative authority. The article also notes his role in preserving the Second State Duma during the “Zurabov incident,” his close cooperation within his ministerial powers with the Third Duma State Defense Commission, and so on. Such a course of the government official turned out to be unacceptable for Nicholas II, which caused resignation of Roediger. The desire of Minister of War Alexander Roediger to improve the state of things in the army through cooperation with moderately liberal deputies (members of the Octobrist Party) aroused suspicions of his political disloyalty, for which there were actually no grounds, and the attempts to solve personnel problems by purging of senior officers brought into question the established personnel policy in such an important area for the tsar as the imperial army. The material analyzed in the article convincingly shows that absolute loyalty to the monarch was the main personnel principle of the last reign. It implied that any attempts of a government official to manage his sphere as he deemed necessary in the interests of the cause rather than as it was understood by the monarch were doomed to fail.
New research on the history of Russian parliamentarism. Review of Tavricheskie chteniya 2020. Aktual'nye problemy parlamentarizma: istoriya i sovremennost'. Mezhdunarodnaya nauchnaya konferentsiya. S.-Peterburg, Tavricheskii dvorets, 10–11 dekabrya 2020 g.: sbornik nauchnykh statei v 2 ch. [Tauride Readings 2020. The current problems of parliamentarism: History and modernity. International scientific conference, St Petersburg, the Tauride Palace, December 10–11, 2020: Collected scientific papers: 2 pts.], edited by A.B. Nikolaev. St Petersburg: Asterion, 2021.
Authors: Murashkina Nataliya Yu.
Published: September 2022

The author analyses the collection of scientific articles of the 14th International Scientific Conference “The Current Problems of Parliamentarism: History and Modernity (2020 Tauride Readings),” held in St Petersburg in December 2020. The review examines the problems and topics of the articles included in the collection as well as the issues tackled during the discussions and the round table. The analysis of various aspects of the activities of the State Duma of the early 20th century plays the lead role in most of the studies presented in the collection.
ANÁLISE COMPARATIVA DO DESEMPENHO ECONÔMICO-FINANCEIRO ENTRE OS SETORES DE CONSUMO DA B3, EM PERÍODOS DE CRISE ECONÔMICA
Authors: Teixeira Emanuela , Oliveira Elis Regina de , Santos Geovane Camilo dos , Ferreira Ronivaldo Alcebíades
Published: September 2022

Esta pesquisa objetiva comparar os indicadores de liquidez, endividamento, lucratividade e rentabilidade das empresas dos setores de Consumo Cíclico e Não Cíclico da Brasil, Bolsa e Balcão (B3), durante quatro períodos (2009-2011; 2012-2014; 2015-2017; e 2018-2020). Foram utilizadas as técnicas quantitativa, descritiva e documental, com aplicação de testes de Wilcoxon, Friedman e Mann-Whitney. O Setor de Consumo Cíclico foi mais afetado, com reduções significativas de Liquidez Geral (LG) e Liquidez Seca (LS); com redução significativa de Margem Líquida (ML), Margem Ebitda (ME), Retorno Sobre o Ativo (ROA) e Retorno Sobre o Patrimônio Líquido (ROE) de 2012-2014 para 2015-2017. O Setor de Consumo Cíclico apresentou maior média de LC do primeiro triênio para o segundo triênio, e maior LG. Esse trabalho corrobora com outros estudos, indicando aos stakeholders que em períodos de crises o Setor de Consumo Cíclico é mais afetado por flutuações econômicas.
DISTRIBUIÇÃO DO VALOR ADICIONADO DE EMPRESAS DO SETOR DE ENERGIA ELÉTRICA: UMA ANÁLISE COMPARATIVA DAS REGIÕES BRASILEIRAS
Authors: Caldas de Oliveira Edison , Lima Altoé Stella Maris , Suave Ricardo
Published: September 2022

O presente estudo comparou a distribuição do valor adicionado de empresas do setor de energia elétrica, a partir das categorias da Demonstração do Valor Adicionado (DVA), entre as diferentes regiões brasileiras. A partir dos percentuais de distribuição, foram calculadas as médias dos percentuais das regiões. Comparou-se médias a partir de análise gráfica e de análise estatística por meio dos testes Kruskall-Wallis e Wilcoxon. Verificou-se que a região sul possui as empresas que mais destinam parte da riqueza gerada para pessoal e para impostos, taxas e contribuições. Outro destaque se refere à região centro-oeste, por possuir as empresas com maior destinação da riqueza às categorias de remuneração de capitais próprios e outros, e menor destinação às categorias impostos, taxas e contribuições e remuneração de capitais de terceiros. Quanto à análise estatística das diferenças entre as regiões, os testes indicam que a categoria pessoal foi a única com diferenças.
CPC 47: NOVOS DIRECIONAMENTO OU UMA NOVA INTERPRETAÇÃO?
Authors: Moraes da Silva Tatiane , Gonzales Alexandre
Published: September 2022

Em 2014, com o propósito de eliminar inconsistências e fragilidades das normas anteriores, o International Accounting Standards Board (IASB) e o Financial Accounting Standards Board (FASB) emitiram o IFRS 15 (ou Pronunciamento Técnico CPC 47 para empresas brasileiras) – Receita de Contrato com Cliente. Dentro deste contexto, o objetivo deste trabalho foi comparar o CPC 47 com o pronunciamento anterior, o CPC 30 – Receitas, para entender quais foram as mudanças apresentadas a partir da nova norma. Após análise teórica dos pronunciamentos, complementou-se a pesquisa com a análise das notas explicativas das empresas dos setores de Telecomunicações, Medicamentos e Outros Produtos e Material Aeronáutico e de Defesa, com o intuito de verificar quais os ajustes foram publicados por este grupo de empresas sob a justificativa da adoção do CPC 47. Adicionalmente, realizou-se a discussão do tema via focus group como forma de capturar a percepção dos ajustes decorrentes do CPC 47 vividos por especialistas da área contábil. Para a análise do resultado da discussão do focus group, utilizou-se a ferramenta NVivo® para a aplicação da metodologia análise de conteúdo como forma de minimizar possíveis inferências sobre o tema discutido. Os resultados mostraram que os ajustes capturados, tanto via nota explicativa, quanto focus group, estavam em sua maioria alinhados com as expectativas dos estudos teóricos. Com base na análise comparativa das normas, concluiu-se que a nova norma não apresentou alterações relevantes, entretanto, o fato de ter uma norma mais detalhada e/ou diretiva resulta em impactos na contabilidade das empresas.
NÍVEL DE DISCLOSURE DE ENTIDADES DE INCORPORAÇÃO IMOBILIÁRIA
Authors: Vaz Figueira Junior Heraldo , Franzin Rodrigues Karen , Lopes da Silva Fabiana , Pelucio Grecco Marta Cristina
Published: September 2022

Com a entrada em vigor da IFRS 15 Receita de Contrato com Cliente e diante da dissonância de entendimento sobre o momento do reconhecimento das receitas nos contratos de venda de unidades imobiliárias em empreendimentos em construção no Brasil,  o objetivo desse trabalho é verificar a influência de fatores relativos ao tamanho e ao desempenho da companhia, ao nível de concentração acionária e ao nível de governança corporativa sobre a divulgação de informações dos contratos de compra e venda de unidade imobiliária não concluída, à luz da Teoria da Agência. O estudo apontou uma relação negativa entre a concentração acionária o nível de disclosure, mesmo sentido encontrado com a dummy que representa a participação de companhia no Novo Mercado. O estudo também apontou uma relação positiva com a receita líquida.
PERANAN SUHU DAN KELEMBABAN SELAMA PENYIMPANAN BENIH KEDELAI TERHADAP DAYA KECAMBAH DAN INFEKSI PATOGEN TULAR BENIH
Authors: Ramdan Evan Purnama , Kanny Putri Irene , Pribadi Edi Minaji , Budiman Budiman
Published: September 2022

Kerusakan benih selama penyimpanan dapat disebabkan oleh infeksi patogen tular benih. Akibatnya dapat terjadi penurunan daya kecambah maupun kematian bibit. Suhu dan kelembaban merupakan salah satu faktor penyebab kemunduran fisiologi benih selama penyimpanan. Oleh karena itu, penelitian ini bertujuan untuk menguji pengaruh suhu dan kelembaban selama penyimpanan terhadap daya kecambah dan cendawan patogen yang berasosiasi dengan benih kedelai. Rancangan yang digunakan pada penelitian ini adalah Ranncangan Acak Lengkap yang terdiri dari 3 perlakuan, yaitu suhu dan kelembaban ruang (kontrol), suhu rendah, dan kelembaban rendah. Setiap perlakuan diulang sebanyak 5 kali.  Benih kedelai disiapkan dengan membungkus 10 butir benih dengan kain kasa sejumlah perlakuan dan ulangan. Benih yang telah dibungkus kasa kemudian disimpan pada suhu dan kelembaban ruang, pada suhu dingin 4oC di refrigerator dan kelembaban rendah (30%) pada desikator yang ditambah silica gel. Setelah 3 minggu penyimpanan, benih kedelai ditumbuhkan dengan metode blotter test. Pada 7 hari setelah tanam, benih yang berkecambah dihitung daya kecambah dan daya infeksi cendawan patogen. Data yang diperoleh kemudian dianalisis ragam dan dilanjutkan dengan uji Tukey sebagai pada taraf5%.Hasil penelitian menunjukkan bahwa perlakuan suhu dan kelembaban dapat menjaga mutu benih dengan daya kecambah 96.67-100%. Perlakuan suhu dingin dan kelembaban rendah juga dapat menghindarkan benih kedelai dari infeksi Cladosporium sp. dan Rhizopus sp.