bluuebunny/crossref_metadata_2025 huggingface dataset:
Estimation Of Color Change Of Maxillofacial Silicone Elastomer After Artificial Aging
Authors: Fadhil Alwan Nebras , Abdul Hussein Hamid Mohammed , Ali Muhsin Saja
Published: December 2023

Background: Silicone elastomers are the most widely used maxillofacial materials, however, it is far away from ideal and still progresses through many improvements for replacing the facial defect, maxillofacial prostheses need renewed as early as six months and can last up to 24 months. The color change is the most essential cause for remaking new prostheses.

Aim: The purpose of this study was to assess the color stability of maxillofacial elastomers throughout aging of about one year.

Materials and methods: Ten specimens were prepared from Room Temperature Vulcanazation (RTV) VerSilTal (VST-06) maxillofacial silicone and pigmented using rayon the flocking, the specimens were tested using the color-ometer device before and after subjecting to 46,146, and 317h accelerated weathering. The data were collected, analyzed, and compared using SPSS (V-18) via t-test, accomplished in confidence % 95 and significant P-Value of  (p ≤ 0.05).

Results: Statistical t-test showed that the values of color changes differed among the tested groups (P≤ 0.05). The red wave value increased throughout weathering progress while the green and blue waves were decreased.

Conclusions: This study presented that the color degradation may take place in VST-06 VerSilTal (room temperature vulcanization) silicone elastomers after it was exposed to 46h accelerated weathering and this degradation increased over time.
Evaluation of Antimicrobial Activity of Newly Prepared Calcium Oxide Based Nanosealer Using Agar Diffusion Test
Authors: Adnan Al-Askary Raghad , Hameed Ahmed Sawsan
Published: December 2023

Aim of the study: The antimicrobial activity of a root canal sealer can increase the success rate of endodontic treatments. The key of antimicrobial properties of calcium based sealers laid in their composition and alkalinity. The invention and applications of newer materials are quintessential in every field especially in endodontics. This reality has led to growing interest in the use of biomaterials products that comprised of both mineral and organic components as those in the teeth. This study was performed to assess the antibacterial activity of newly prepared calcium oxide based nanosealer and compare the result with BioRoot sealer

Materials and methods: The CaO nanopowder was firstly prepared from calcinated cowrie seashell using ball milling and ultrasonic irradiation methods, and then the CaO nanopowder was used as the main component in the preparation of an experimental nanosealer powder part. After several pilot studies, the final formula for the prepared sealer that gave the best clinical sealer consistency and properties within the limits of ANSI/ADA Specification No.57/2012 was as the following. The powder part consists mainly of nano CaO (44%) in addition to glutamic amino acid, zirconium oxide (20nm), and silica oxide (15-20) nm, while the liquid part consists mainly from distilled water in addition to propylene glycol. The Antimicrobial activity of the prepared sealer was evaluated by agar diffusion test against E.faecalis and E.faecium, after 1, 2, 3, and 7 days of incubation at 37˚C. Zone of bacterial inhibition was measured and analyzed statistically using Independent sample t – test at (p=0.05) levels.
Fracture strength and color stability of direct composite veneer using different materials
Authors: Hamoudi Alsunboli Mohammed , Hasan Jasim Haider
Published: December 2023

Aim: The purpose of this study was to compare the fracture resistance and color stability of three different restoration materials: Nano composite, flowable composite, and Nanohybid composite.

Materials and Methods: 45 removed human maxillary premolar teeth for orthodontic treatment were chosen. The teeth were divided into three experimental groups, each consisting of fifteen teeth: Direct composite veneers constructed of Nano - composites were employed to fix the teeth in Group A. (Z350 XT, 3M, USA). Group B: Flowable composite was used to directly veneer teeth (G-aenial Universal flo GC, Japan). Group C: Direct composite veneers made of Nanohybid composite were used to reconstruct teeth (G-aenial GC, Japan). Each tooth in groups A, B, and C had a copyplast template made prior to preparation using a 1 mm thick vacuum-pressed polyethylene plastic template. Standard preparations (intra enamel) were made for all teeth in experimental groups using ceramic veneer set burs. By injecting flowable composite via a hole formed in a copyplast template, Group B is restored. In Groups A and C, the buccal third (Bucco-palatally) of the template was filled with restorative material using a plastic tool before being positioned on the tooth and squeezed until it made contact with the unprepared tooth surface. All specimens' baseline colors were assessed using a spectrophotometer (Vita Easyshade, Ivoclar VivadentAG, Schaan, Liechtenstin). After baseline color measurement, each group of laminate veneers were subjected to immersion solutions (Tea bags, Lipton). Each specimen's color values were once again measured with the same spectrophotometer,

 

and the color change values (ΔE) were computed. Using a universal testing equipment, the fracture strength was evaluated.
PROPERTIES INVESTIGATION OF POLYESTER RESIN COMPOSITE MATERIALS AND PRODUCTS
Authors: Shulgin V. , Muravlov V. , Popovych N. , Bondar L. , Petrash O.
Published: December 2023

The use of composite materials in construction is a promising direction due to their potential to reduce costs and improve the operational characteristics of building structures. The results of this study will allow to determine the optimal formulations and manufacturing technologies of polymer composite materials for use in construction. In this paper, a detailed analysis of the composite material based on polyester resin (polymer sand concrete) used for the manufacture of hatch covers for manholes in water supply and sewage systems is carried out. The main components of the considered composition are quartz sand, unsaturated polyester resin, hardening accelerator - cobalt naphthenate solution and hardener - benzoyl peroxide.

As part of the study, the improvement of the composite material’s properties is also considered by adjusting the technological modes of formation. Special attention was paid to the analysis of the hardness of the samples after the research, since this parameter determines the resistance of the material to wear. The effect of different ratios of these components on the physical and mechanical properties of the final material was studied. It was experimentally determined how the consumption of polyester and hardener affects the compressive strength, bending strength, impact toughness and hardness of the composite material.

To obtain optimal characteristics, the STATISTICA 12 software package was used to specify the values of the factors that lead to maximum compressive and bending strength. The results of the research are presented in the conclusions in the form of quantitative indicators that indicate the optimal composition to achieve high physical and mechanical characteristics. The response surfaces of the variation factors’ influence on the properties of interest are shown.
Keywords: composite material, polymer sand concrete, quartz sand, polyester resin, hardening accelerator - cobalt naphthenate solution and hardener - benzoyl peroxide
TRENDS IN THE DEVELOPMENT OF VIRTUAL REALITY TOOLS IN THE GLOBAL DESIGN PRACTICE
Authors: Shataliuk Yu. , Shataliuk D.
Published: December 2023

The article is devoted to consideration of general trends in the development of virtual reality in architecture. It has been determined that the conditions for the usage of VR in architecture are becoming more and more favourable as each year these technologies are improved and their availability increases. As a result of the increasingly widespread use of smartphones, virtual reality applications have appeared that can be easily downloaded and installed on a phone. From the variety of tools for working with virtual reality, those that can be useful for applicability in architecture were selected. The chosen relevant tools were systematised into two categories: hardware and software. Recommendations for their application, depending on the request or stage of the project, are presented. It has been determined which form of virtual reality, devices, and software are the most suitable for the analysis, simulation, and design of the architectural environment.
Special attention in the research is paid to artificial intelligence and the analysis of its influence on VR in architecture. The speed of development, compared to the traditional methods, economic expediency, and enhanced realism are singled out among the advantages of artificial intelligence. The prospects for VR development in architecture and its impact on the profession are examined.
VR can also be used to create innovative new designs for buildings, allowing architects to explore the potential of materials, textures, and shapes in a way that was not possible before. Architects and designers can use VR to create, experimentalise, and refine design solutions virtually before starting construction.
In the future, VR will become an integral part not only of the design process but also of presentation and approval. It is a powerful tool that helps establish communication between all the process participants. VR in architecture has enormous potential, the implementation of which will provide high social and economic results.
Keywords: virtual reality, augmented reality, architectural environment, design, artificial intelligence.
A Meta-Analysis of the Effectiveness of Transcranial Magnetic Stimulation and Transcranial Direct Current Stimulation as Therapy of Insomnia
Authors: Carolina Mastari Devina , Virenia Wariki Windy Mariane , Momole Ansye , Khosama Herlyani , Warouw Finny , Pertiwi Junita Maja
Published: December 2023

Objective: Insomnia serves as the most common sleep disorder. Transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS) are amongst most popular treatment for insomnia. This research aimed to determine the comparative effectiveness of TMS and tDCS as therapies for insomnia.Methods: PubMed/MEDLINE, ScienceDirect, Google Scholar, ResearchGate, Wiley Library Online, and Neurona were used to search for randomized controlled trials (RCTs) comparing TMS/tDCS with sham group in insomnia. Meta-analysis was done to determine the effectiveness of TMS and tDCS as a therapy for insomnia. Weighted mean difference were computed and reported with its 95% CI. Heterogeneity was reported with I2. Risk of bias was assessed using the Cochrane Risk of Bias 2 tool. Subjective pooled-analysis was done using Mann-Whitney U test with p<0.05.Results: From a total 1,000 publications, 15 studies were included, revealing varying types of insomnia as follows: 26.7% comorbid depression, 13.3% comorbid pain, 13.3% involving athletes, 13.3% primary insomnia, 6.7% due to medication, 6.7% comorbid polio, 6.7% comorbid Sjogren’s syndrome, 6.7% comorbid stroke, and 6.7% comorbid Parkinson’s disease. From 15 studies, four homogenous articles were made for pooled-analyses, which included two studies on TMS and two studies on tDCS in insomnia comorbid depression. tDCS improved sleep onset latency, N2, and REM latency better than sham. TMS (2.29, 95% CI: 1.82–2.76) was superior to sham in improving the subjective quality of sleep, and tDCS (1.05, 0.68–1.43) with p=0.121.Conclusion: No significant differences were found between TMS and tDCS as therapies for insomnia. Most RCTs studying TMS/tDCS in insomnia reported high comorbidity with depression.
Emotional Dysregulation in Shift Workers
Authors: Lee Yu Jin
Published: December 2023

Shift work continues to increase in frequency in industrial society and accounts for more than 20% of workers in modern society. Previous studies have reported that shift work is a representative environmental factor that disrupts circadian rhythm and is associated with various physical and mental problems, including sleep problems. In particular, problems with circadian rhythm are closely related to difficulties in emotional regulation that cause mood disorders. In this review, we reviewed previous studies on emotion dysregulation in shift workers and examined past studies on the neuroscience basis for these problems. If neurobiological research yields results on shift workers’ vulnerability to emotional and sleep problems, it would be possible to suggest ways to prevent the adverse mental effects of shift work.
RADIOPHARMACEUTICALS BASED ON FIBROBLAST ACTIVATION PROTEIN INHIBITORS IN ONCOLOGICAL PRACTICE
Authors:   Nonprofit Organization National Cancer Institute of Ministry of Health of Ukraine, Dzhuzha D. O. , Myasoyedov S. D. ,   Shupyk National Healthcare University of Ministry of Health of Ukraine
Published: December 2023

The review is devoted to the application of the new perspective class of radionuclide tracers, based on inhibitors of the fibroblast activation protein (FAP), which is a marker of cancer-associated fibroblasts of microenvironment of most malignant tumors. FAP inhibitors (FAPI) can be labeled by a wide spectrum of radionuclides, which can provide both radionuclide diagnostics and radionuclide therapy. It was showed, that the diagnostic efficacy of FAPI positron emission tomography/computed tomography (PET/CT) in various cancers is similar to 18F-fluorodesoxyglucose-PET/CT or superior. The FAPI radiopharmaceuticals (RP) have some advantage compared to 18F-fluorodesoxyglucose (FDG): no need for special preparation and diet, fast imaging with high contrast, and increased sensitivity in region with high glucose metabolism. FAPI-PET/CT may be an important addition to conventional methods in all stages of diagnostic process in oncology, especially when 18F-FDG cannot be used. It is need to further wide prospective investigations for assessing of diagnostic efficacy of FAPI-RP and determination of indications for its using. Key words: fibroblast activation protein; radiolabeled fibroblast activation protein inhibitors; FAPI-PET/CT; radionuclide diagnostics; radionuclide therapy.
TNF-α AND IONIZING RADIATION: THE ROLE IN THE PATHOGENESIS AND TREATMENT OF PLASMA CELL MYELOMA (review)
Authors:   Bogomolets National Medical University, Liubarets T. F.
Published: December 2023

The review presents data from the literature on the role of Tumor necrosis factor-α (TNF-α) and ionizing radiation (IR) in the pathogenesis and treatment of plasma cell myeloma (PCM). There was analyzed disturbance of regulation of functioning of this cytokine, which affects the interaction of the immune system with substrate plasma cells under the influence of negative external factors, including ionizing radiation IR. Modern directions of therapy of this disease using the latest technologies are presented, in particular CAR T-cell therapy, which will allow to optimize in the future treatment of this disease and, thus, improve the quality and life expectancy of PCM patients. Key words: plasma cell myeloma, cytokines, TNF-α, CAR T-cell therapy.
RELAÇÃO ENTRE SÍNDROME DE BURNOUT E SATISFAÇÃO NO TRABALHO
Authors: Pereira Branco Karoline , Carolina Guerra Ana , Batista Ferreira Eric
Published: December 2023

Este trabalho teve como objetivo pesquisar a propensão de um grupo de docentes universitários de uma instituição federal de ensino a desenvolverem a síndrome de burnout, bem como objetivou procurar fatores associados à satisfação /insatisfação no trabalho e questões sociodemográficas que influenciam sua ocorrência. Para isso, foram disponibilizados questionários para o levantamento de variáveis sociodemográficas, o questionário S20/23 para avaliar a satisfação no trabalho e o questionário MBI que avaliou a magnitude das dimensões da síndrome de burnout nos docentes. Os resultados foram obtidos por meio da análise de estatísticas descritivas e análise de regressão linear múltipla pelo método MQO. Verificou-se que os profissionais analisados têm baixas chances de desenvolver a síndrome, visto que apresentaram baixos níveis de despersonalização e altos níveis de realização profissional. Entretanto, a pesquisa apontou para níveis preocupantes de Exaustão Emocional. Por fim, embora de não tenham sido encontrados preditores significativamente estatísticos para a ocorrência da exaustão emocional nos docentes, verificou-se que os níveis de satisfação intrínseca no trabalho têm influência nos valores observados de despersonalização e de realização profissional, bem como as variáveis sexo, estado civil e cor da pele também impactam nos níveis deste último.
PALAVRAS-CHAVE: Despersonalização. Exaustão Emocional. Realização Profissional. Preditores.
AVALIAÇÃO DA DISTRIBUIÇÃO DA CARGA TRIBUTÁRIA DO BRASIL UTILIZANDO OS MICRODADOS DA PESQUISA DE ORÇAMENTOS FAMILIARES (POF 2017-18)
Authors: Da Hora Jefferson , Nogueira José Ricardo
Published: December 2023

Considerando que o bem-estar social é sensível à desigualdade, este artigo busca avaliar a distribuição da carga tributária do Brasil, utilizando a Pesquisa de Orçamentos Familiares (POF 2017-18), além de mensurar o nível de progressividade/regressividade do sistema tributário. Os microdados da POF 2017-18 são trabalhados, de forma a estratificar as famílias em decis de renda per capita, além de obter as informações sobre o pagamento dos tributos diretos, por domicílio, bem como, seu perfil ao longo dos estratos de renda. Também é calculada a distribuição da carga tributária indireta do consumo e, em detalhe, da alimentação, na qual são utilizadas as alíquotas efetivas. Com os resultados, é possível obter a distribuição da carga tributária total, assim como, calcular índices de mensuração da progressividade/regressividade. É observado que os tributos diretos são progressivos, além disso, que os tributos indiretos são regressivos sob a ótica da renda e neutros sob a ótica do gasto e, finalmente, que a distribuição da carga tributária total é proporcional, sob o aspecto da renda. No mais, os índices de mensuração da progressividade/regressividade calculados reforçam os resultados obtidos anteriormente, incluindo que o imposto de renda é substancialmente progressivo e que os tributos indiretos da alimentação são fortemente regressivos.
Palavras-chave: Progressividade e Regressividade. Pesquisa de Orçamentos Familiares (POF). Carga Tributária. Microdados.
Belarusian scientific journals as a source of professional communication
Authors: Kulazhanka U. G. , Miliunets A. Ch.
Published: December 2023

Publishing the findings of scientific research in reputable scientific publications affects the rate of knowledge dissemination. At the same time, most Belarusian scientific journals has been revising their publishing concept to meet the criteria set by citation indexes.

The paper aim is to determine the status of the Belarusian scientific periodicals in the conditions of the developing model of electronic scientific communication in the post-Soviet states.

At the first stage, the stream of publications by Belarusian researchers was identified, and the positive dynamics in 2011 to 2021 was recorded. Documents were analyzed by type and thematic categories. At the second stage, the list of Belarusian scientific journals was analyzed for their indexation in the science citation databases, the availability of the periodical website, the positive dynamics of the titles on the List of scientific publications for publishing the findings of dissertations recommended by the Higher Attestation Commission of Republic of Belarus (List of publications of the Higher Attestation Commission), etc.

Based on the analysis, it was revealed that Belarusian scientific journals are widely represented in the Russian Science Citation Index (RSCI); at the same time, there is a certain “stagnation” in their entering the international citation indices – Scopus or Web of Science. The authors emphasize the challenge of Belarusian scientific periodicals insufficient presence in the Internet, and of the absent websites of some periodicals.
Penanganan Ispa Pada Balita Dengan Terapi Komplementer (Uap, Pijat dan Herbal) di Muara Lebak RW 10 Kelurahan Pasir Jaya Kecamatan Bogor Barat Kota Bogor
Authors: Istiani Hari Ghanesia , Nurtika Baiq Laely , Muliawati Mariam
Published: December 2023

Penyakit yang paling sering diderita oleh balita adalah Infeksi Saluran Pernapasan Akut (ISPA), ISPA merupakan singkatan dari Infeksi Saluran Pernapasan Akut yang berarti masuknya kuman ke dalam saluran pernapasan yang berlangsung sampai dengan 14 hari.(1)
 Infeksi Saluran Pernapasan Akut merupakan salah satu diantara beberapa penyebab paling sering pada kematian anak-anak di negara berkembang Penggunaan Terapi Komplementer dan Terapi Pijat pada Balita dapat membantu untuk mengurangi dampak kejadian penyakit khususnya ISPA. Tujuan pengabdian masyarakat ini memberikan pengetahuan kepada orangtua tentang penanganan ISPA pada Balita serta terapi komplementernya di Muara Lebak RW 10 Kel. Pasir Jaya Kec. Bogor Barat Kota Bogor, sasaran dari kegiatan ini adalah ibu yang memiliki balita dan para kader. Metode yang dilakukan yaitu memberikan edukasi tentang penanganan ISPA dengan terapi komplementer kepada balita. Kegiatan ini dilakukan pada 02 Februari 2023 pada pukul 09.00-11.00 WIB. Hasil didapatkan bahwa tingkat pengetahuan peserta sebelum diberikan penyuluhan didominasi oleh kategori kurang yaitu presentase sebesar 54%, dan setelah dilakukan penyuluhan tentang Edukasi Penanganan ISPA dan Terapi Komplementer (UAP,Pijat,Herbal) Berdasarkan hasil setelah pelaksanaan edukasi didapatkan bahwa tingkat pengetahuan peserta meningkat, yaitu didominasi dengan kategori baik sebesar 68%.
Arheobotanička analiza „liburnske“ keramike s
lokaliteta Nadin – Gradina
Authors: Knežić Dolores , Šoštarić Renata , Čelhar Martina
Published: December 2023

U radu su analizirani biljni makroostaci na glinenim ulomcima s organskim primjesama s nalazišta Nadin – Gradina u sjevernoj Dalmaciji. Ulomci keramičke posude većih dimenzija skladišne namjene potječu iz jednog zatvorenog naseobinskog konteksta (SJ 419) datiranog radiokarbonskom metodom u razdoblje starijeg željeznog doba, odnosno u vremenski okvir posljednje četvrtine 9. st. pr. Kr. do sredine 8. st. pr. Kr. Organske primjese korištene su od najranijh vremena u smjesi za izradu keramike kako bi se utjecalo na svojstva konačnog keramičkog produkta. Takvi sušeni ili pečeni keramički predmeti sadrže tragove korištenja biljnih primjesa u vidu otisaka i biljnih ostataka. Identificirani biljni ostaci većim dijelom potječu od ostataka vršidbe žitarica: pšeno, stabljike i listovi te pljeve i ostaci klasa. Na temelju analize otisaka i ostataka biljnih primjesa bilo je moguće determinirati krupnozrne žitarice: ječam (Hordeum sp.) i pšenicu (Triticum sp.) te sitnozrne: proso/muhar (Panicum/Setaria sp.). Od ostalih nalaza pronađeni su tragovi masline (Olea europaea) i drijena (cf. Cornus mas) te skupine trava (Poaceae). Otisci i ostaci biljnih primjesa u keramici često ostaju nezamijećeni, iako predstavljaju vrijednu dopunu klasičnoj analizi biljnih makrofosila, a time i dodatne podatke o gospodarskim strategijama i okolišu zajednice koja je keramiku proizvela.
The Role of Language in a Dynamic Situation of Globalization
Authors: Iskandarsyah Siregar
Published: December 2023

The central and vital role and function of language make it very interesting to continue to be explored, questioned, and studied. The Republic of Indonesia has an official language used by its citizens, namely Indonesian. This language aims to unite the Indonesian nation, which is multicultural or has ethnic and cultural diversity, so that there is no distance separating fellow Indonesian citizens from hundreds of ethnic groups, according to the 1928 Youth Pledge Convention. What must be realized now is the use of Indonesian, which needs to be stronger. The weakness is not that it is not used at all but foreign terms that enter public discussion and tend to be considered more prestigious. This study uses a qualitative descriptive method that refers to literature sources and the results of previous studies. The existence of the Indonesian language can decline when most Indonesian people are happy and proud to use a foreign language considered more respectable and classier. However, the condition for the Indonesian language's existence is still in a safe stage. The Indonesian language can continue to exist by continuing to preserve it by adhering to the overall context and linguistic rules and developing its constructions by the needs and desires of civilization.
Synthesis of manganese oxide from manganese ore of bajaur agency khyber Pakhtunkhwa (KPK), Pakistan
Authors: Zafar Uzma , Bhatti Muhammad Arif , Mehmood R
Published: December 2023

In the present work manganese sulphate developed from the Bajaur (KPK, Pakistan) manganese ore was utilized successfully for the synthesized Manganese Oxide chemically by an alkali-oxidation of manganese sulphate using the co-precipitation method. The advantages of this eco-friendly co-precipitation method include quick and easy preparation, simple control of particle size, and cost-effective composition using local ore. Because of the readily available raw materials and the controlled reaction conditions, this method is widely used in industry. Scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR) were used to characterize the synthetic manganese oxide. Fourier transforms infrared spectroscopy (FTIR) Infrared reveals that the O-Mn-O vibrational mode occurs in pure manganese oxide at wavelengths between 600 and 500 cm-1. The chemical composition was obtained by EDX analysis and confirmed the presence of Mn and O in the sample. Experimental optimization was done for the manganese oxide precipitation conditions. The findings show that a variety of parameters have an impact on the product yield; the precursor ratio and reaction temperature are the most important variables, and the reaction time and pH value have the greatest impact on the quality of crystallization.
Bangladesh J. Sci. Ind. Res. 58(4), 221-230, 2023
Confronting Anxiety in the Era of COVID-19: Investigating the Prevalence and Impact on Daily Life in Bangladesh
Authors: Islam Md Rashadul , Sony Sabrina Amita , Imran Md Ashik , Disha Sadia Sinty , Murshed Mortuja Kamal , Talukdar Sutapa , Pramanik Shishir Kanti , Masud Mostafa Kamal , Kalam Azad Muhammad Abdul , Al Shoeb Mohammad Abdullah
Published: December 2023

Background: The COVID-19 pandemic has brought about unprecedented stress levels and has significantly impacted daily life activities, including changes in food patterns, sleep disturbances, and reduced physical activity. This survey study aims to analyze the pervasiveness of generalized anxiety disorder (GAD) among Bangladeshi adults and its association with daily life activities.
Methods: A randomized phone number generator was utilized to approach 1438 individuals aged 18 and above, out of which 412 participants volunteered for the study. Participants' anxiety level was estimated by using the GAD-7 score.
Results: Out of the 412 respondents, 11.89% experienced severe anxiety, while 17.72% and 39.32% suffered moderate and mild anxiety, respectively. Severe anxiety was more prevalent among women (16%) than men (9.54%). The study found that sleeping for less than eight hours was associated with an increased likelihood of severe anxiety (OR = 4.87), while fewer changes in food habits (OR = 0.27), less online exposure (OR = 0.01), and engaging in some physical activity (OR = 0.20) were associated with the reduced likelihood of anxiety.
Conclusion: This survey study highlights to give more emphasis of monitoring anxiety during a public health emergency like the COVID-19 pandemic. The findings of this study establish a significant correlation between GAD and everyday life activities, emphasizing the need to prioritize mental health initiatives during such unprecedented times.
Bioresearch Commu. 10(1): 1378-1385, 2024 (January)
Long-Term Developmental Assessment of Children Recovered from Hypernatremia
Authors: Huq Sayeeda , Sarker Shafiqul Alam , Jahan Khursheed , Shaheen Nazma
Published: December 2023

Purpose: Imbalances in sodium result in acute neurologic symptoms such as seizures and impaired mental status. Studies investigating the long-term consequences of hypernatremia on cognitive, motor, and language development in children are limited. The aim of this study was to assess the long-term impact of hypernatremia on children’s cognitive, motor, and language development.
Methodology:It was an observational study conducted from March 2016 to March 2017 in Dhaka Hospital of icddr,b. In this study,211 children with acute watery diarrhea accompanied with hypernatremia (serum sodium level 150 mmol/L) who had already been enrolled in a previous observational study were prospectively followed for one year.The objective was to investigate if there are any long term neurologic and developmental consequences of hypernatremia in those children.  Physical, cognitive, motor, and language development as well as expressive or receptive expression of the children were assessed using a standard tool at the time of discharge (Baseline) and 12 months after discharge (End line). We also assessed IQ in a subgroup of children > 36 months (n=57) using the Wechsler Preschool and Primary Scale of Intelligence in parallel.
Results: Among the 211 participants, developmental assessment on motor, cognitive, and language development test was done on 140 (66.3%) children. The mean age of the children at the time of discharge from the hospital (baseline) was 7.9±4.5 months. Compared to mild (serum Na 150 mmol/L to less than 160 mmol/L), and moderately (serum Na 160 mmol/L to 169 mmol/L) hypernatremia, children with severe hypernatremia (serum sodium >170mmol/L) significantly had lower mean scores on the motor, fine motor, and language development score at baseline after adjusting age and weight for the age z score. Although there was an improvement in motor, language, and socioemotional scores, significant improvement was only observed with cognitive function at the end line (p=0.002). In Mmultiple regression after adjusting for potential confounders such as levels of hypernatremia, parents’ education, age of the child, and WAZ, these factors were showed significantly associated with the cognitive function of children. There was no difference in mean IQ level performed at the end-line among the children with different level of hypernatremia (mild, moderate or severe).
Conclusion: Children with hypernatremia had poor developmental scores in cognitive, motor, language, and socio-emotional domains at the time of recovery from hypernatremia. However, other than cognitive score, there was no significant improvement in motor or language development at 12 months in children recovering from hypernatremia. Further studies are therefore warranted to reveal any association of motor or language deficit with neurological deficit in those children beyond 12 months.
Bioresearch Commu. 10(1): 1386-1392, 2024 (January)
Adenoid Hypertrophy Managed With Artemisia Cina Dilution: A Study of Two Cases
Authors: Habib Sheak Ahshan , Zakaria Md , Hai Md Abdul , Amin Md Ruhul , Hasan Nazmul
Published: December 2023

Adenoid hypertrophy, is the enlargement of adenoid tissues in the nasopharynx, a common concern among children and often exhibits with nasal congestion, mouth breathing, snoring, and sleep disturbances. Spontaneous healing of enlarged adenoid is common in adolescents and adults, however, in this case study, we present two instances of pediatric patients who demonstrated adenoid-related health issues. After a thorough evaluation, and based on the principle of symptom similarity Artemisia cina was prescribed; this treatment continued for three consecutive weeks, and a follow-up lateral x-ray of nasopharynx was obtained one more week later. The use of homeopathic preparation of Artemisia cina appeared to ease their symptoms. This outcome suggests that Artemisia cina may hold promise as a homeopathic option for managing adenoid-related concerns in pediatric patients. However, we acknowledge that further research and a larger sample size are necessary to establish the usefulness of this approach.
Bioresearch Commu. 10(1): 1449-1452, 2024 (January)
Analysis of Microbiological Quality and Antibiotic Resistance Patterns in Milk Supply Chain
Authors: Rinky Farhana , Reza Sompa , Nowar Abira , Ghosh Supriya , Rahman Asma , Alim Sharmin Rumi
Published: December 2023

The widespread consumption of milk for its nutritional value and health benefits brings the risk of milk-borne diseases due to the presence of various microorganisms, including antibiotic-resistant pathogens. This has led to an increased focus on ensuring the safety of milk products across the supply chain by dairy industries. The study aimed to evaluate microbiological parameters and detect multi-antibiotic-resistant pathogens at three specific supply points and to explore the association between the presence of residual antibiotics and the resistant isolates in milk samples. About 50 milk samples, including raw, soon-after-processed, packaged marketed pasteurized, and UHT milk, were subjected to microbiological analysis. This involved assessing the total bacterial count (TBC) and total coliform count (TCC), conducting antibiotic susceptibility tests through disk and well diffusion assays, detecting virulence genes in multi-antibiotic resistant isolates using gene-specific PCR, and analyzing residual antibiotics by HPLC. The study revealed that the quality of raw milk samples was unacceptable (TBC >4.5x107 CFU/mL and TCC >5.6x104 CFU/mL), while pasteurized samples from processing plants had lower counts than those from retail stores (TBC >5x105 CFU/mL and TCC >1.6x104 CFU/mL) indicating post-pasteurization contamination. About 70.37% of the isolates were Gram-negative, with Escherichia coli (21.4%) and Vibrio (18.8%) being the most prevalent. Resistance to antibiotics was substantial, particularly against ampicillin (86.3%), tetracycline (76%), and ciprofloxacin (58.9%). Gene-specific PCR analysis detected uidA, oprL, and oprI virulence genes in multi-drug-resistant Escherichia coli and Pseudomonas sp. respectively. The study also revealed a direct association between the presence of residual antibiotics and the resistant isolates, emphasizing the need for dairy industry improvements. As high bacterial counts in milk can pose health risks by fostering antibiotic-resistant pathogens, it is essential to mitigate microbiological contamination in the milk supply chain through the implementation of various precautionary measures.

Bioresearch Commu. 10(1): 1462-1473, 2024 (January)
A influência do diabetes gestacional no agravamento da COVID-19
Authors: Mota Gabriel Silva Costa , Carvalho Silas Santos , Santos Adrielle Gomes , Oliveira Thaynara Sampaio de , Silva Rafaella Bispo da , Gusmão Luana Lopes , Purificação Michely Machado da
Published: December 2023

Introdução: O impacto do tratamento medicamentoso em pacientes com COVID-19 pode agravar o quadro de hiperglicemia do paciente enquanto as complicações do COVID-19 como o dano endotelial causado por inflamações, a glucotoxidade e a tempestade de citocinas podem contribuir no alto risco de complicações tromboembólicas e no dano aos órgãos nos pacientes de diabetes.  Objetivo: Abordar a influência do diabetes gestacional no agravamento da COVID-19. Metodologia: Revisão integrativa de literatura com artigos publicados entre os anos 2004 e 2023, através da busca na plataforma PubMed, em revistas indexadas e de impacto científico, nos idiomas português e inglês. Resultados: Foram selecionadas 10 publicações e submetidas à análise de conteúdo. Conclusão: O Diabetes e o COVID-19 tem uma relação de agravamento mútuo, causado, por exemplo, pelos medicamentos no tratamento para o COVID-19, pela sintomatologia das doenças, pelos danos causados aos órgãos que podem agravar o quadro do enfermo e pelas dificuldades e riscos que as gestantes com Diabetes Mellitus Gestacional foram submetidas por causa dessa pandemia.
SANITASI TTU PADA BANGUNAN DI KANTOR KESEHATAN PELABUHAN (KKP) KELAS 1 SURABAYA
Authors: Kumaerah Ratu
Published: December 2023

Sanitasi tempat-tempat umum merupakan usaha-usaha untuk mencegah dan mengawasi kerugian kibat dari tempat-tempat umum yang memiliki potensi terjadinya penularan, pencemaran lingkungan, ataupun gangguan kesehatan lainnya. Penelitian ini bertujuan mengetahui kondisi fasilitas sanitasi gedung yang ada di wilayah kerja Kantor Kesehata Pelabuhan (KKP) Kelas 1 Surabaya. Dalam penelitian ini menggunakan jenis penelitian deskritif yaitu melakukan pengamatan langsung ke lokasi dan menggambarkan keadaan lokasi yang meliputi keadaan bagian dalam bangunan, bagian luar bangunan, fasilitas sanitasi dan lain-lain sesuai di lapangan. Hasil yang didapatkan, Asrama haji sukalilo telah dilengkapi dengan sarana prasarana yang memadai untuk menunjang kenyamanan dan keamanan para jemaah haji. Dengan adanya sarana prasarana yang memadai ini diharapkan dapat memberikan pengalaman yang baik bagi jemaah haji selama menunaikan ibadah. Sanitasi bangunan pada gedung Gapura Surya Nusantara, peneliti dapat menyimpulkan bahwa bangunan telah memenuhi syarat sanitasi bangunan dengan di dukung oleh beberapa hasil kondisi bangunan baik, ruangn bangunan kuat, kondisi penyediaan air memenuhi syarat, pencahyaan susuai standar baku mutu, kamar mandi bersih dan vektorpun tidak ditemukan pada setiap sudut ruangan.
HAND GESTURE RECOGNITION
Authors: Badagan Sana , R Deeksha , Sai Teja K Tarun , J Chetan ,   DSATM
Published: December 2023

Continuous and dynamic gesture recognition is a vital research area that aims to develop systems capable of interpreting and understanding hand gestures involving continuous motion and temporal dynamics. This project focuses on addressing the challenges associated with recognizing and analyzing gestures that go beyond static poses. By leveraging techniques such as temporal modeling, motion analysis, and deep learning, the goal is to develop algorithms and models that can robustly track and interpret the fluidity and expressiveness of human hand movements. The project aims to enhance the understanding of gesture sequencing, timing, and smooth transitions between different poses and gestures. The research outcomes will contribute to the advancement of intuitive human-computer interaction, enabling users to express themselves more naturally and seamlessly in applications such as virtual reality, gaming, and humanrobot interaction. Through the use of relevant datasets and advanced algorithms, this project seeks to explore novel approaches in continuous and dynamic gesture recognition and pave the way for future advancements in this field
PREDICTING STOCK PRICES WITH MACHINE LEARNING USING COMPARATIVE ANALYSIS OF RANDOM FOREST ALGORITHM
Authors: Khandagale H. P , Patil Rajvardhan , Patil Shreyas , Bhosale Dhanashri ,   Department of Technology, Kolhapur
Published: December 2023

The precise forecasting of stock market prices presents a tough challenge, owing to the crucial volatility and details of the market. In this research paper, we tackle this challenge by introducing a stock market prediction model grounded in the Random Forest algorithm. Our study centers on historical trading data encompassing a diverse array of stocks and ETF funds, harnessing the capabilities of AI technology and machine learning methodologies to forecast and scrutinize stock prices through regression analysis. The outcomes underscore the Random Forest model's capacity to achieve commendable accuracy in stock prediction, thereby offering invaluable insights for both institutional and individual stock investments. These models rely on technical indicators as inputs, with the closing value of stock prices serving as the predicted variable. The results not only underscore the effectiveness of our proposed approach in constructing predictive models for stock price projection but also highlight the potential of Machine Learning algorithms to reveal valuable insights into the dynamics of stock market activity. Moreover, our paper investigates the exploration of diverse Machine Learning models, encompassing Linear Regression, Support Vector Regression, Decision Tree, Random Forest Regressor, and Extra Tree Regressor. Their implementation has proven instrumental in achieving precision in stock price prediction and has furnished fresh perspectives into the intricate interplay between buyers and sellers in the stock market. The evaluation of these models is grounded in their accuracy in predicting stock prices, using both closing values and stock prices as crucial metrics. Consequently, our research shines a spotlight on the substantial potential of Machine Learning algorithms in decoding stock market price dynamics, thus contributing significantly to our comprehension of the stock market's intricate workings
AN INTERACTION BETWEEN BOARD ATTRIBUTES AND EARNINGS MANAGEMENT OF LISTED MANUFACTURING COMPANIES IN NIGERIA
Authors: Akindele Jamiu Adeniyi , Marsidi Asri , Bakare Taophic Olarewaju , Aliyu Almustapha Alhaji
Published: December 2023

The study investigated an interplay between board attribute and earnings management of listed manufacturing companies in Nigeria. This study tested some board attributes indicators (audit fee, board independence, and board size), and earnings management was proxied using discretionary accruals using a sample of forty-two (42) manufacturing companies listed on Nigerian Exchange Group while purposeful sampling techniques were used to sampled from the population, covering the study period from 2010 to 2021. The data were analyzed using the Generalized method of moment by the use of E-View 12 econometric software and multivariate- regression model. The findings of the study show that there is a positive and statistically insignificant relationship between audit fees and earnings management. The study therefore concludes that a positive and statistical relationship exists between board attributes and earnings management of listed manufacturing companies in Nigeria. The study consequently recommends that ethical standards should be encouraged by the regulatory agencies if not mandated.
Analysis of face stability for shallow shield tunnels in sand
Authors: Qiang Sihan , Zhao Lizhi , Wang Xuehai , Li Xiaoming , Wang Fengnian
Published: December 2023

The stability of the tunnel face is the key problem in shield tunnel construction. This paper focuses on the face stability of a shallow tunnel in sand. Numerical simulation and theoretical analysis are combined to study the limit support pressure and failure zone. Firstly, numerical simulation is employed to study the collapse of the tunnel face, obtaining the limit support pressure and collapse zone. A new failure model suitable for shallow tunnels is constructed based on these numerical simulations. Then, an analytic solution for the limit support pressure is derived using limit analysis upper bound theory. The accuracy and applicability of this proposed model are verified by comparing it with numerical results and classical analytical models. Through this research, it is found that the proposed model provides a more accurate description of situations where soil arches cannot be formed for shallow tunnels in sand, leading to higher accuracy in calculating the limit support pressure. The influence of various factors on stability of the tunnel face is analyzed, revealing mechanisms of tunnel face collapse.
Combining Karhunen–Loève expansion and stochastic modeling for probabilistic delineation of well capture zones in heterogeneous aquifers
Authors: Gao Wenfeng , Shao Guangyu , Zhu Tengqiao , Jiang Simin
Published: December 2023

The delineation of well capture zones (WCZs), particularly for water supply wells, is of utmost importance to ensure water quality. This task requires a comprehensive understanding of the aquifer’s hydrogeological parameters for precise delineation. However, the inherent uncertainty associated with these parameters poses a significant challenge. Traditional deterministic methods bear inherent risks, emphasizing the demand for more resilient and probabilistic techniques. This study introduces a novel approach that combines the Karhunen–Loève expansion (KLE) technique with stochastic modeling to probabilistically delineate well capture zones in heterogeneous aquifers. Through numerical examples involving moderate and strong heterogeneity, the effectiveness of KLE dimension reduction and the reliability of stochastic simulations are explored. The results show that increasing the number of KL-terms significantly improves the statistical attributes of the samples. When employing more KL-terms, the statistical properties of the hydraulic conductivity field outperform those of cases with fewer KL-terms. Notably, particularly in scenarios of strong heterogeneity, achieving a convergent probabilistic WCZs map requires a greater number of KL-terms and stochastic simulations compared to cases with moderate heterogeneity.
The Biocontrol of Plant Pathogenic Fungi by Selected Lactic Acid Bacteria: From Laboratory to Field Study
Authors: Gwiazdowski Romuald , Kubiak Krzysztof , Juś Krzysztof , Marchwińska Katarzyna , Gwiazdowska Daniela
Published: December 2023

Plant diseases caused by pathogenic fungi generate large losses in crops and pose a threat to human and animal health. Since the European Green Deal put a strong emphasis on the need to reduce the use of chemical plant protection, interest in biological control has been growing. The present study aimed to investigate the efficacy of lactic acid bacteria (LAB) isolated from silages in the control of pathogenic fungi through in vitro, mini-plot, and field experiments. The tested LAB showed antifungal activity in vitro towards strains from the Fusarium, Alternaria, Rhizoctonia, Colletotrichum, and Sclerotinia genera; however, only five strains reached an activity ≥ 400 AU/mL towards all pathogenic fungi. The selected strains demonstrated high efficacy in reducing disease symptoms in plants in the mini-plot and field experiments. In the mini-plot experiment, stem smut of rye and wheat common bunt were reduced in the range 34.5–94.7% and 24.8–99.6%, respectively. In the field experiments, the efficacy of LAB in the control of rye and wheat disease differed and reached over 90% in some trials. The effectiveness of LAB in the control of seedling blight did not exceed 70%. A significant increase in yield (from 42.86 to 195.65%) was observed mainly in wheat cultivation. The increase in rye yield was observed only in chosen trials. No phytotoxicity was observed. The results indicate the potential possibilities of using LAB as a biocontrol agent.
Changes in Gut Microbiota Associated with Parity in Large White Sows
Authors: Bu Yage , Feng Lingli , Xu Di , Zhang Shuai , Liang Liang , Si Jinglei , Lu Yujie , Liu Qiaoling , Yan Gang , Wang Yubin , Lan Ganqiu , Liang Jing
Published: December 2023

As one of the most critical economic traits, the litter performance of sows is influenced by their parity. Some studies have indicated a connection between the gut microbiota and the litter performance of animals. In this study, we examined litter performance in 1363 records of different parities of Large White sows. We observed a marked decline in TNB (Total Number Born) and NBH (Number of Healthy Born) We observed a marked decline in TNB (Total Number Born) and NBH (Number of Healthy Born) among sows with parity 7 or higher. To gain a deeper understanding of the potential role of gut microbiota in this phenomenon, we conducted 16S rRNA amplicon sequencing of fecal DNA from 263 Large White sows at different parities and compared the changes in their gut microbiota with increasing parity. The results revealed that in comparison to sows with a parity from one to six, sows with a parity of seven or higher exhibited decreased alpha diversity in their gut microbiota. There was an increased proportion of pathogenic bacteria (such as Enterobacteriaceae, Streptococcus, and Escherichia–Shigella) and a reduced proportion of SCFA-producing families (such as Ruminococcaceae), indicating signs of inflammatory aging. The decline in sow function may be one of the primary reasons for the reduction in their litter performance.