bluuebunny/crossref_metadata_2025 huggingface dataset:
Epidural analgesia-efficacy and feto-maternal outcome: A cross sectional study
Authors: Kharde Anup , Swapnil Mane , Rutuja Phulambrikar
Published: May 2022

The delivery of an alert and active baby into the arms of a conscious and pain free mother is one of the most exciting and rewarding experiences in medicineEpidural analgesia is considered one of the most effective methods for pain relief during labor, and the intrapartum use of epidural analgesia has substantially increased over the previous two decades.

To study efficacy of epidural analgesia in labour and its feto-maternal outcome.

Present descriptive observational study was conducted at a tertiary care hospital. The study was conducted over the period one year from 2019 to 2020. Pregnant women reporting for delivery at study setting were the study population. Healthy pregnant primigravidae or multigravida women who had gestational age of greater than 37 weeks without any risk factors, in true labour with vertex presentation of fetus were included after obtaining an informed consent.

Total number of patients were 50 with mean age 23.57 ± 2.73. Mode of delivery in 70% (35) parturient was spontaneous while 14% (07) and 6% (03) had forceps and vacuum delivery respectively. The remaining 10% (5) underwent lower section caesarian section (LSCS). The mean Apgar score of babies at one minute and at 5 minutes was 9.0±1.5and 9.6±1.4 respectively. Majority of the mothers were relieved from pain after epidural analgesia.

Present study concludes that Epidural analgesia provides good pain relief in majority of the patients without any evidence of foeto-maternal compromise.
Post catheterization urine analysis in lower?segment caesarean section patients
Authors: Shah Prashant , Devi Gayathri , Shah Neelima , Sawant Vasudha
Published: May 2022

To assess the effect of duration of catherization on urine analysis and on first voiding time after removal of catheter in postoperative period after caesarean section.

Patients who have undergone caesarean section from June 2020 to June 2021. The catheter was in-situ post operatively. Urine sample from each patient was analyzed for routine microscopy before catheterization as well as after removal of catheter. Midstream clean catch urine was collected in sterile container and sent for urine routine analysis. As per duration of catheter in situ we divided the patients in four groups

Patients with catheter in situ- up to 24 hours, 24 to 48 hours, 48 to 72 hours, > 72 hours.

Factors like urgency, frequency, dysuria and time required to void first time after removal of catheter were taken into consideration. > 4 pus cells in microscopy were taken as UTI.

Urinary urgency and frequency were 91% in patient with catheter in situ for >24 hours.

Out of 50 with duration of 1 to 3 hours catheter in situ, 48 had moderate dysuria, 10 with duration > 3 hours catheter in situ had dysuria in post- operatively. Of 35 with > 2 days of catheter in situ, 31 had UTI in postoperatively. Time taken to void the bladder initially was increased after removal of catheter in postoperatively.

We have concluded that use of catheter for >24 hours is associated with increased incidence of urinary infection and more discomfort at first voiding.
Carbetocin, the front runner for post partum haemorrhage in heart disease complicating pregnancy at a tertiary care hospital
Authors: Sharif Amreen , Janaki Vellanki
Published: May 2022

: Post Partum Heamorrhage (PPH) is responsible for 47% of maternal mortality in India and one quarter of maternal deaths globally. Lack of expertise, lack of proper cold chain for oxytocin and cost limitations of heat stable carbetocin are major hurdles to prevent PPH. Restrained options for safer uterotonics in heart disease complicating pregnancy are a major concern.

This study was conducted on 30 patients with heart disease complicating pregnancy who delivered at a tertiary care centre. All patients were administered single dose of carbetocin 100 mcg IM immediately after delivery and observed for development of PPH.

: Carbetocin prevented PPH in 73.33% cases. Among 20% of COVID-19 positive patients, only one case had PPH. Major contributory factors in patients developing PPH include anemia before delivery, use of anticoagulant in antenatal period, instrumental delivery and high CARPREG 2 score. Less hemodynamic side effects even in patients with high CARPREG 2 score was appreciated.

Carbetocin is a hemodynamically safer and effective uterotonic in heart disease complicating pregnancy. Increasing its availability and implementation in current guidelines is the way forward.
Choriangioma of placenta – A rare case report
Authors: Sathyamurthy Kaavya , Moideen Nilufer , Kurude Vilas N
Published: May 2022

Chorioangiomas are benign tumours of the placenta, characterised by AV shunting within placenta leading to fetal anaemia, cardiomegaly and hydrops. Maternal complications are also possible such as polyhydramnios, APH and Mirror syndrome. Chorioangiomas of a large size (> 4 cm) can create complications for the fetus and expectant mothers. Chorioangioma is often associated with unfavourable effects on the mother as well as on the fetus. The following article is the case report of a patient who presented with polyhydramnios associated with chorioangioma of placenta with Preterm premature rupture of membranes.
A rare case report of anterior vaginal wall cyst
Authors: Mudanur S S R , Jayasree J , Chand A Eshwer
Published: May 2022

Vaginal wall mucinous cyst is very rare benign condition, and it is non-invasive in nature, it can be mistaken as urethral diverticulum, inclusion cyst, Gartner cyst. Cyst may cause symptoms if it increase in size then cyst excision is the treatment of choice.

35 yrs old woman presented with chief complaints of mass per vaginum since 6yrs, white discharge per vaginum since 6yrs, difficulty in micturation since 6 months, dysparunia since 3 months, on examination diagnosis is second degree UV prolapsed with cervicitis with cystocele and rectocele with anterior vaginal wall cyst, vaginal hysterectomy with cystocele and rectocele repair with excision of anterior vaginal wall cyst specimen sent for HPR and shows uterus with cervicitis with ulceration, secretory endometrium and benign mucinous cyst of ant vaginal wall.

Vaginal wall mucinous cyst is rare condition, cyst is completely excised but long term surveillance to be done for recurrence.
Adhesion Control for Freight Train Based on Improved Sliding Mode Extremum Seeking Algorithm and Barrier Lyapunov Function
Authors: Cheng Xiang , He Jing , Zhang Changfan , Huang Gang , Huang Yishan
Published: May 2022

Adhesion control system is an essential component for a freight train, which aims to optimize its performance of traction, the design of the adhesion control system remains a significant challenge. One of the main challenges is the optimal creep-speed is difficult to acquire in real-time, the other one is the parameters of resistance were not available in advance. Meanwhile, adhesion is a nonlinear dynamical process. In this paper, an improved sliding mode extremum seeking virtual sensors is proposed for the issue of acquiring the optimal creep-speed in real-time; a particle swarm algorithm (PSO)-based estimation method is proposed for the issue of uncertain resistance parameters; and finally, an adhesion controller is designed based on the barrier Lyapunov concept.
DC Component Extraction of Notch Filter Algorithm for Active Power Filters
Authors: Jampana Bangarraju , Askani Jayalaxmi , Veramalla Rajagopal
Published: May 2022

This work presents a way to handle the DC component of input signals for PLL and notch filter applications, which are utilized for filtering and synchronization. The input signal of a DC component may be due to some sort of malfunction, or it may be the result of the structure and restrictions of the measurement/conversion procedures. This part makes the system's loop oscillate at low frequencies and no filter can fully filter them out because that would significantly harm the system's dynamic response. The proposal involves augmenting the PLL structure with a new loop. It is basic architecturally and in contrast to a currently presented method and it does not detract from the algorithm's high-frequency filtering level. This Orthogonal Signal Generators (OSG) control algorithm is used for active power filter to maintain unity power factor, neutral current compensation using star/three single transformer & current harmonics mitigation. The MATLAB/Simulink results are demonstrated for the above stated Power Quality (PQ) problems.
Fault Detection for a Nonlinear Switched Continuous Time Delayed System Using Machine Learning and Self-Switched UKF
Authors: Chatterjee Sayanti
Published: May 2022

The main objective of this research is to propose a novel machine learning based fault detection algorithm for a nonlinear switched continuous system (NSCS) with time delayed measurements. A simulation model has been established through the analysis of the relevant constraints such as estimation errors derived from self-switched time- delayed (TD) Unscented Kalman Filter (UKF). Machine learning techniques, specifically probabilistic principal components analysis (PPCA) and the support vector machine (SVM) have been successfully adopted on the database of the proposed model to detect and isolate the faults. ‘Three tank system’, the commonly used bench mark problem, has been re-employed here to prove the efficiency of the proposed estimation and fault detection algorithm. In this work, it is conjectured that the available measurements are time delayed. Through this study, the efficacy of the proposed time- delayed Unscented Kalman Filter (TD-UKF) and Machine Learning based fault detection have been demonstrated on the afore mentioned benchmark problem. The results indicates that Machine learning based algorithm can detect the fault with more accuracy and less false alarm than other statistical methods. The finding of this research can be used for any type of industrial system to detect the faults with better potential and higher range coverage.
Design and Qsar Studies of Benzimidazole Nucleus As Anti-Infective Agents
Authors: Sirvi Sakharam , joshi Deshbandhu , Singh Bhadauria Raghvendra
Published: May 2022

The objective of current study is to design, synthesize the benzimidazoles derivative and evaluate it for anti-malarialactivity by the recently developed Computer Aided Drug Designing techniques with development of new pharmacological active compounds However, a promising approach is needed to use these agents as templates for designing new derivatives with improved properties. The Aim of this project was thus to investigate the potential of the lead compound for future antimalrial drugs. . In order to accomplish this aim a range of synthetic derivatives of Benzimidazoles were prepared and biologically evaluated for Antimalarial activity. 2D Structure of all the designed compounds were draw with the help of chem Draw ultra-version 8.0.3 and exported to window of Chem 3D ultra version 8.0.3 Energy of all the 3D structures were minimized through MOPAC up to RMS gradient 0.001 and saved in MDL Mol file (.Mol) format. )]. In order to examine the predictive power of the QSAR models, the dataset was divided into training set consisting of 32 molecules and test set consisting of 8 compounds in such a way that the utilizing the diversity method in such a way that the structural diversity and a wide range of biological activity in the data set were added. The IC50 values were transformed to pIC50 in order to give numerically larger data values.
Naturoestheticotherapy, Based on E-Coaching with Food Cosmetic Remedy Prepared from Medicinal Plants and Essential Oils Mixtures, Alone or in Combination of Conventional Medicines to Treat Covid-19 Patients and Symptoms.
Authors: Herintsoa RAFATRO , Bezanahary Hanitrinivony ANDRIANOMENTSOA , Hasiniaina Norovololona Angèle RANDRIAMAVO SOLO , Rija Herindrainy RAMANAMPAMAHARANA
Published: May 2022

Introduction: This is the first study to evaluate the family (30) members (98) practice combining specific lifestyle with the use of medicinal plants based on EOM and conventional medicines.
Clinical observation procedures: A considered multi-centric, controlled and single-blind, phase two clinical trial was realized to patients consulted and received in the Antananarivo Naturoestheticotherapy e-Coaching cabinet of Gasy Products Services and those from Covid-19 Treatment Centers, respectively, during twenty-two months: from May 1st, 2020 to March 1st, 2022. Patients were recommended to follow a specific alimentation and behavior lifestyle. Food Cosmetic Remedy, based on medicinal plant and essential oil mixtures with patient’s optional conventional medicines were given to those presenting Covid-19 principal symptom, such as breath shortness accompanied other indicated symptoms or confirmed medical diagnoses/tests.
Outcomes and conclusion: Inhalation of EOM were immediately stopped breath shortness, combining medicinal plants based on essential oil and conventional medicines was psychologically help and physically reinforce the organism to improve Covid-19 symptoms. Food Cosmetic Remedy (combination of medicinal plant and essential oil mixtures) was quickly recovered patients from principal symptoms and reduced time care and long-Covid-19 period. No patient death was registered during the studied observation period.
Enhancing group self- and career construction counselling: A review of outcome research
Authors: Maree Jacobus G.
Published: May 2022

This article reviews the outcomes of five purposely selected group career construction research projects conducted in a developing country context. Thematic data analysis was done on the results of these projects to identify qualitatively the strengths and areas for development (weaknesses) of the approach followed in these projects. The findings demonstrated the value of career constructing in contexts that differed substantially from the context in which the career construction counselling was originally developed. Overall, the quantitative findings in regard to career adaptability revealed that the women benefited more from the intervention than the men. The findings in regard to career decision-making difficulties also uncovered gender differences. The qualitative outcomes revealed that the participants’ psychological self as an autobiographical author benefited more from the intervention than either the social actor or the motivated agent. Future research should focus on the application of group career construction counselling with larger groups, using instruments based on career construction counselling theory developed locally. Moreover, given current developments (including the impact of the Covid-19 pandemic on employment), special emphasis should be placed on research among the unemployed.

Keywords: psychological self, integrative group career construction, Global South, unemployment
Precariousness in the time of COVID-19: A turning point for reforming and reorganizing career counselling for vulnerable workers
Authors: Di Fabio Annamaria , Svicher Andrea
Published: May 2022

The aim of the present article is to purpose new career counselling perspectives for vulnerable workers in the time of COVID-19 recession. We summarize perspectives on vulnerable workers following a recently advanced taxonomy on the work precarity framework characterized by three broad categories: precarity of work (i.e. fear and concern associated with the continuity of employment), precarity at work (i.e. psychosocial or physical safety at work, including discrimination, harassment, and unsafe working conditions), and precarity from work (i.e. uncertainty and insecurity due to maintaining employment that does not satisfy the basic needs of workers). These three facets of precariousness are frequently experienced by vulnerable workers, and they are related to poorer mental and physical health. The COVID-19 pandemic dramatically exacerbated this trend for vulnerable workers. Thus, suggestions for mitigating the impact of the current crisis are presented. Our perspective deals with the psychology of sustainability, sustainable development, and the psychology of working theory. In this framework, vocational psychologists could reform and reorganize specific career counselling practices for vulnerable workers, promoting sustainable and decent work and inclusivity. This could be achieved by applying four key points. 1) Enrich career counselling interventions with the processes of self-identity, reflection, and reflexivity on what constitutes actual sustainability for vulnerable workers in terms of professional and personal development. 2) Promote the use of an evidence-based methodology in accordance with the accountability principles for the 21st century. 3) Advocate to enrich available services with positive primary preventive strength-based actions and interventions through timely differentiated career counselling strategies. 4) Encourage applied research and practices to find new ways to balance resources with evidence-based efficacy; for example, by using the power of the audience in group-based life design counselling.

Keywords: career counselling, decent work, precarious work, psychology of sustainability, vulnerable workers.
Total Leukosit dan Diferensial Leukosit Ayam Pedaging yang diberi Tepung Belatung sebagai Pakan Tambahan Ransum
Authors: Lubis Barata Sultan , Ardana Ida Bagus Komang , Siswanto Siswanto
Published: May 2022

Tepung belatung Hermetia illucens memiliki kandungan protein 37,31% dan lemak 39,05%, sehingga dapat digunakan sebagai pakan tambahan dalam ransum. Sebagai bahan yang kaya dengan protein dan lemak, belatung black soldier fly (BSF) baik pula hubungannya dengan pembentukan sel darah putih (leukosit). Penelitian ini bertujuan untuk mengetahui total leukosit dan diferensial leukosit ayam pedaging yang diberi tepung belatung sebagai pakan tambahan dalam ransum. Sebanyak 24 ekor ayam pedaging jantan digunakan dalam penelitian ini. Ayam pedaging dikelompokkan menjadi empat sesuai dengan perlakuan: perlakuan P0 (kontrol), perlakuan P1 (1% dari pakan komersial), perlakuan P2 (2% dari pakan komersial), dan perlakuan P3 (3% dari pakan komersial). Perlakuan diberikan mulai hari ke-14 sampai hari ke-35. Sampel darah diambil dari vena pectoralis sebanyak 3 mL pada hari ke-36. Jumlah leukosit dan diferensial leukosit dihitung menggunakan auto hematology analyzer. Data yang telah diperoleh dianalisis menggunakan sidik ragam satu arah. Hasil penelitian menunjukkan total leukosit 81,92-97,98×103/µL, persentase heterofil 28,50-37,50%, persentase eosinofil 0%, persentase basofil 0%, persentase limfosit 51,67-64,17%, dan persentase monosit 7,33-10,83%. Berdasarkan hasil penelitian dapat disimpulkan bahwa penambahan tepung belatung ke dalam pakan komersial meningkatkan total leukosit, persentase limfosit, dan menekan persentase heterofil ayam pedaging.
PENGARUH MODERASI DARI COUNTRY OF ORIGIN DAN PRODUCT TYPE TERHADAP HUBUNGAN ANTARA BRAND EQUITY TERHADAP REPURCHASE INTENTION DAN WORD OF MOUTH DALAM BRAND APPLE IPHONE [EFFECT OF MODERATION OF COUNTRY OF ORIGIN AND PRODUCT TYPE ON THE RELATIONSHIP BETWEEN BRAND EQUITY AND REPURCHASE INTENTION AND WORD OF MOUTH IN BRAND APPLE IPHONE]
Authors: Kamal Kevin , Wuisan Dewi
Published: May 2022

This study aims to examine whether there is a positive effect of brand equity on repurchase intentions and word of mouth moderated by perceived value and country of origin in the Apple iPhone brand as a product type. The sampling technique used in this study is non-probability sampling, namely purposive sampling in which the respondents are Apple iPhone users in Indonesia. The sample of this study found 260 respondents with data collection methods using electronic questionnaires. Data processing was carried out by statistical analysis, validity, and reliability using the Partial Least Square – Structural Equation Modeling (PLS-SEM) method and processed using SmartPLS 3.0 software. The results showed that the brand equity variable had a positive influence on the variables of repurchase intention and word of mouth promotion. Likewise, the variable type of product and country of origin both have a positive moderating effect on the relationship between brand equity and repurchase intention, and brand equity on word of mouth.

BAHASA INDONESIA ABSTRACT

Penelitian ini bertujuan menguji apakah terdapat pengaruh positif dari brand equity terhadap repurchase intention dan word of mouth yang dimoderasi oleh perceived value dan country of origin dalam brand Apple iPhone sebagai product type. Teknik pengambilan sampel yang digunakan dalam penelitian ini adalah non-probability sampling, yaitu purposive sampling di mana responden adalah pengguna Apple iPhone yang berada di wilayah Indonesia. Sampel penelitian ini berjumlah 260 responden dengan metode pengumpulan data menggunakan kuesioner elektronik. Pengolahan data dilakukan dengan analisis statistik, validitas, dan reliabilitas yang menggunakan metode Partial Least Square – Structural Equation Modeling (PLS-SEM) dan diolah menggunakan software SmartPLS 3.0. Hasil penelitian menunjukkan bahwa variabel brand equity memiliki pengaruh positif terhadap variabel repurchase intention dan word of mouth. Begitu juga dengan variabel product type dan country of origin, keduanya memiliki pengaruh moderasi yang positif terhadap hubungan antara brand equity terhadap repurchase intention, serta brand equity terhadap word of mouth.
UNDERSTANDING CUSTOMER LOYALTY IN INDONESIA QUICK SERVICE RESTAURANT INDUSTRY
Authors: Juliana Juliana , Pramezwary Amelda , Oktaviani Dhana Calista , E Felicia Tania , Benly Michelle A.
Published: May 2022

In the restaurant industry, customer loyalty has become the most important strategic goal. The impact of service quality dimensions on customer loyalty is investigated using the SERVQUAL scale's dimensional structure in fast food restaurant service environments. Pizza Hut is a well-known fast-food chain that appeals to people of all ages, from children to the elderly. Pizza Hut has locations throughout the city as well as internationally. Each branch's level of service is unquestionably different. Pizza Hut Indonesia will be the subject of this study. A sample of 100 respondents is used to create and test research hypotheses. Quantitative research is the form of research that we used in this study. A questionnaire was used to collect data from everyone who has ever visited Pizza Hut Indonesia. PLS-SEM was utilized to perform the data analysis. According to the data, total consumer loyalty is 44,8 percent. As a consequence of this research, consumer loyalty at Pizza Hut Indonesia is substantially influenced by service quality.
The Effect of Various Concentration BAP (6-Benzyl Amino Purine) on Orchid Growth (Macodes petola (Blume) Lindl.) In-Vitro
Authors: Muchsin Muchfa Eprilia , Supriatna Ateng , Adawiyah Ayuni , Darniwa Adisty Virakawugi
Published: May 2022

Macodes petola (Blume) Lindl. has an attractive of leaves veins motif with letters pattern, so it has a high economic value. Tissue culture technique is reported as the best way of plant propagation in short time. BAP (6-Benzyl Amino Purine) has a role in stimulating shoot growth with a certain concentration. The purpose of this study was to determine the effect of Various Concentration BAP (6-Benzyl Amino Purine) on Orchid Growth (M petola (Blume) Lindl.) in vitro. This study used a completely randomized design (CRD) with 4 concentration BAP levels (0; 0.5; 1; 1.5 ppm) with 3 replication. Based on the results of the study, it showed that up to 60 DAP (Day After Planting) the composition of the media with a concentration of 0 ppm BAP had a higher average value for the increase in the stem height, number of shoots and number of roots, namely 1.77±0.798 cm, 2.4 ± 1,528 shoot and 2.4 ± 2,082 root. In contrast to the concentration of 1.5 ppm at this concentration it has a low average value the parameters of stem height, number of shoots and number of roots.
Public Mass Protest Promotions: Formation of an Inclusive Political Institute
Authors: Nisnevich Y.
Published: May 2022

This article analyzes the formation process of a new inclusive political institution, which is represented by public mass protests of a non-violent nature. Such actions, the number of which is constantly increasing, take place in states with both authoritarian and democratic governments, and they have become an institutionalized repertoire of political action under all types of government regimes. The socio-information environment, where social and info-communication processes are closely intertwined as a result of mass use of social networks, blogs and other Internet resources, as well as wide spread of mobile telephony and the mobile Internet, has become not only a favorable setting for preparing, organizing and holding mass protest actions without clear leaders and organizational structures, but also a catalyst for such actions. Ever improving information and communication technologies as well as the nature of social media and other Internet resources increase the inclusiveness of mass protests, expand the circle of their participants, simplify the organization process and improve its efficiency. Under authoritarian regimes, when all traditional institutions and mechanisms to influence the authorities and to publicly express attitude to their decisions and actions are blocked, mass protests provide certain opportunities to put pressure on the government, and also serve as an institutional factor in the transformation of such regimes. Under democratic regimes, when in the face of post-industrial civilizational transit, traditional institutions and mechanisms of political involvement and influence on the current government appear to be insufficiently effective, and there is a dysfunction of democratic political systems due to their delayed adaptation to new conditions, public mass protests act as a new inclusive political institution designed to compensate for the dysfunction.
Nonlinear Dependence and Spillovers between Currency Markets and Global Financial Market Variables
Authors: Jiang Zhuhua , Arreola Hernandez Jose , McIver Ron P. , Yoon Seong-Min
Published: May 2022

The widespread integration and growing dependence among currency, stock and commodity markets make these markets often very vulnerable to shocks and at risk of collapse at the same time. As a result, these trends threaten the sustainability of the entire financial system. In this study, we explore the spillovers and nonlinear dependences between the seven major foreign ex-change rates, crude oil and gold prices, a global stock price index, and oil and stock implied volatility indices as proxy variables for global risk factors by em-ploying directional spillover network approach. We also use multi-scale de-composition method and nonlinear causality test between these variables to capture multi-level relationships at short and long horizons. Major findings are summarized as follows. First, from the multi-scale decomposition analysis, we identify that Granger causality test results and the direction and strength of return spillovers change with the level of decomposition. Second, the results of nonlinear causality tests show variation in both the significance and direction of Granger causality relationships between the decomposed currency and other series at different timescales, especially for the decomposed oil, gold, and OVX series. Third, the measured directional spillover indices identify the EUR as the largest contributor of connectedness to the other series. The central role of the EUR is a net transmitter of connectedness to gold, oil, the GBP, JPY, and CHF.
Desenvolvimento de modelo agroclimático para o município de Cachoeiras de Macacu – RJ
Authors: Rodrigues do Carmo Luiz Felipe , Paiva Célia Maria , Figueiredo Menezes Wallace , De Carvalho dos Santos Gabryele
Published: May 2022

A atividade agrícola, de modo geral, tem significativa importância para a economia brasileira. Para que se tenha um rendimento saudável dos grãos, faz-se necessário o entendimento da variabilidade e das mudanças climáticas da região de cultivo. A temperatura do ar e a precipitação são as principais variáveis responsáveis pelas modificações nesses padrões. Portanto, uma boa compreensão dos impactos provocados nas culturas por essas alterações pode ajudar na realização de uma atividade agrícola saudável e sustentável por parte dos agricultores. Dessa forma, o objetivo deste trabalho é a elaboração de um calendário agrícola para os pequenos agricultores do Município de Cachoeiras de Macacu, no Rio de Janeiro, para auxiliá-los no planejamento e manejo de diferentes culturas no campo, bem como na ideal utilização dos recursos hídricos, segundo o calendário elaborado. Para tanto, as seguintes etapas foram executadas: cálculo do excedente e déficit hídrico e a aptidão agroclimática para o Município de Cachoeiras de Macacu, situado no estado do Rio de Janeiro; elaboração de um calendário agrícola sustentável para cultivo e plantio de culturas anuais e perenes produzidas na região e cálculo do risco agroclimático para as culturas, de modo a norteá-los em relação ao risco associado à disponibilidade hídrica. Os resultados preliminares mostraram que as culturas mais favoráveis do ponto de vista da aptidão foram o açaí, a cebola, a goiaba e o milho.
Palavras-Chave: Simulação Agroclimática; Risco Agroclimático; Cachoeiras de Macacu.
economia circular no ordenamento jurídico brasileiro
Authors: Scholz Karl Júlia , Karl Alexandre Augusto
Published: May 2022

As premissas do desenvolvimento sustentável, assim como os novos modelos de negócio sob o rótulo verde, se intensificam e propõem mudanças significativas no modus operandi de consumo e produção. Por estarem orientados à proteção ambiental, requerem maior responsabilidade no que concerne aos impactos socioambientais das cadeias produtivas. Nesse contexto, nota-se a importância de regulamentar a transição às economias verdes, alicerçadas na economia circular, que, não obstante as vantagens econômicas, sociais e ambientais, no cenário brasileiro retrata caráter deficitário em sua regulamentação jurídica. O presente estudo busca apresentar o panorama legislativo da economia circular no Brasil, analisando os desafios de sua institucionalização e aplicação. Para tanto, conduziu-se uma revisão da literatura como meio de identificar estudos afins ao tema. Ao longo da pesquisa, identificou-se um grande potencial para o Brasil, mas há uma falha em sua regulamentação normativa. Como resultado, observa-se que, não obstante os elogios à Política Nacional de Resíduos Sólidos, não há, atualmente, uma norma jurídica impositiva para a transição de um modelo linear para um modelo circular de produção. As certificações, órgãos de controle, barreiras comerciais e as próprias exigências do mercado externo têm sido meios de incentivo à institucionalização da economia circular no Brasil.
**Palavras-Chave**: Economia Circular; Legislação; Política Nacional de Resíduos Sólidos.
Análise e modelagem computacional do processo de manufatura de fitas adesivas em uma empresa do Polo Industrial de Manaus
Authors: Martins Lucas Atila , De Melo Freires Vitoria , De Lima Nascimento Adna Thais , Parente Rossetti Segadilha Bismarck , Da Silva Ribeiro Willian Maycon , Solart Leal Leandra , De Souza Bezerra Alessandro , Higino Pereira da Silva Roberto
Published: May 2022

A estratégia de investir em inovação, seja no produto ou no processo, é uma necessidade das empresas para que consiga permanecer em uma economia dinâmica, veloz e de concorrência acirrada. A indústria 4.0 é uma realidade mundial e as fábricas instaladas no Polo Industrial de Manaus (PIM) precisam se reestruturar para absorver os avanços tecnológicos desse novo paradigma industrial. Tendo isso em vista, esta pesquisa, subsidiada por investimentos em pesquisa e desenvolvimento (P&D) na Amazônia Ocidental, propõe otimizar uma célula produtiva em uma empresa situada no PIM que atue no setor de fitas adesivas. O estudo foi baseado em um dos pilares da indústria 4.0: simulação digital de eventos discretos utilizando o software Flexsim®. Os dados para a elaboração do modelo foram coletados no período de junho a novembro de 2021 e tratados com a ferramenta ExpertFit®, suplemento estatístico do software. Devido ao grande número de produtos processados pela empresa, o presente estudo limitou-se a aprofundar sua análise em apenas em um tipo de fita, entretanto, seus resultados podem ser espelhados para todos os produtos dessa família. A construção e posterior análise comparativa de sete cenários com propostas otimizadas chegou à uma solução ideal com reduções significativas, e que caso implementasse no processo físico, resultaria em redução de custos para a empresa por meio do aumento da produtividade e redução dos estoques do processo produtivo, atingindo, assim, os objetivos de otimizar a célula de produção.
Palavras-Chave: Indústria 4.0; Simulação Computacional; Otimização de Processos; Software Flexsim®.
Comprehensive review of a Digital Maturity Model and proposal for a continuous digital transformation process with Digital Maturity Model integration
Authors: Pham Minh Hoang , Pham Thi Thanh Hong
Published: May 2022

In recent years, digital transformation has become one of the most popular trends for enterprises worldwide. The global trend of digital technologies and the COVID-19 pandemic have made the growth speed of digital transformation steadier than ever. In this condition, practitioners and academic researchers believe that the Digital Maturity Model is one of the most effective weapons in helping managers and the workforce manage to transform their businesses digitally. However, the Digital Maturity Model (DMM) is a type of maturity model (MM) that is relatively new in model development and digital maturity assessment methodologies, especially when integrated into an extensive digital transformation process. With this paper, the authors aim to conduct a comprehensive review to clarify the current state of the DMM field, including its essential characteristics, popular elements belonging to its structures, the number of methods, and techniques used in developing and applying them. In addition, these papers identify significant areas of research underway. Moreover, the authors raise some challenges for the field in the capture of results by reviewing them: i) the need to standardize its component names; ii) a contextualized but low-cost DMM for SMEs to use in their business; iii) the need for positioning DMM applied processes in a master digital transformation process and in a dynamics context that help applications of DMM more efficient. The authors proposed a solution for the third challenge through a conceptual model integrating DMM into a continuous digital transformation process.
Keywords: Digital Transformation; Digital Maturity Model; Continuous Transformation Process; Change Management.
Dinâmica de distribuição e fontes potenciais de hidrocarbonetos aromáticos policíclicos para sedimentos de superfície e bivalves de um estuário altamente antropizado
Authors: Azevedo Netto Adriana , Farias de Souza Patricia , Da Silva Lima Leonardo , Silva Vieira Khauê , de Freitas Delgado Jessica , Ramos Menezes Carolina , Vieira Neves Charles , Baptista Neto José Antônio , Monteiro da Fonseca Estefan
Published: May 2022

O Sistema Estuarino de Santos (SES), localizado no sudoeste do Brasil, apresenta importância econômica estratégica para o país devido à presença do maior porto brasileiro e por ser uma das áreas mais industrializadas. Por outro lado, este ambiente é prejudicado pelas atividades industriais e de dragagem, que podem causar o aumento de poluentes ambientais e a biodisponibilidade de compostos potencialmente perigosos. Neste contexto, os hidrocarbonetos policíclicos aromáticos (HPA) foram avaliados em quinze estações de amostragem distribuídas ao longo do estuário. As concentrações de HPA foram analisadas em amostras de sedimentos superficiais e em tecidos de duas espécies bivalves (Crassostrea rhizophorae e Perna perna). Além disso, analisou-se a salinidade da coluna d'água, a matéria orgânica dos sedimentos e o tamanho dos grãos para verificar sua influência sobre o acúmulo de contaminantes. As concentrações totais de sedimentos HPA variaram entre N.D. e 1711,79 ng g-1 de peso seco (p.s.). Os níveis de hidrocarboneto bivalve variaram entre 88,38 e 988,76 ng g-1 (p.s.). As taxas de HPA calculadas revelaram que os compostos de HPA encontrados na área estudada têm origem petrogênica e pirolítica. Uma comparação das concentrações de HPA encontradas neste estudo com aquelas listadas nas diretrizes de qualidade de sedimentos (SQGs) indicou que os efeitos biológicos adversos sobre a biota são eventualmente esperados.
Palavras-chave: Hidrocarbonetos Policíclicos Aromáticos; Contaminação; Atividades Iindustriais.
Распространение вариантов вируса SARS-COV-2, вызывающих озабоченность (VOC) на основе количества их геномов, депонированных в базу данных GISAID за неделю с 14.05.2022 г. по 20.05.2022 г.
Authors: Дмитриева Людмила
Published: May 2022

В обзоре представлена информация по актуальным геновариантам вируса SARS-COV-2, циркулирующим в настоящее время, геномные проследовательности которых размещены в международной базе данных GISAID за неделю с 14.05.2022 г. по 20.05.2022 г.
Pulsating Spinal Arachnoid Cyst as a Hidden Aggravating Factor for Thoracic Spondylotic Myelopathy
Authors: Takahata Masahiko , Watanabe Takamasa , Endo Tsutomu , Ogawa Yuki , Miura Souya , Iwasaki Norimasa
Published: May 2022

Case:

We report 3 cases of thoracic myelopathy caused by vertebral osteophytes and coexisting intradural spinal arachnoid cyst (SAC), which was difficult to diagnose on preoperative magnetic resonance imaging. Intraoperative ultrasound sonography revealed spinal cord impingement because of osteophytes and a pulsating intradural SAC. Repeated pincer compression on the spinal cord seemed to be associated with their paraparetic symptoms.

Conclusion:

In treating patients presenting with unexplained progressive myelopathy with small ossified lesion in the thoracic spine, close attention should be paid to a coexisting SAC as a hidden aggravating factor for thoracic myelopathy.
CyberKnife Xsight versus Fiducial-based Target-tracking: A Novel 3D Dosimetric Comparison in a Dynamic Phantom
Authors: Klein Thomas J , Gill Suki , Ebert Martin A , Grogan Garry , Smith Warwick , Alkhatib Zaid , Geraghty John , Sc Alison JD , Brown Alan , Rowshanfarzad Pejman
Published: May 2022

Background: The CyberKnife Xsight lung-tracking system (XLTS) provides an alternative to fiducial-based target-tracking systems (FTTS) for non-small-cell lung cancer (NSCLC) patients without invasive fiducial insertion procedures. This study provides a method for 3D independent dosimetric verification of the accuracy of the FTTS compared to the XLTS without relying on log-files generated by the CyberKnife system. Methods: A respiratory motion trace was taken from a 4D-CT of a real lung cancer patient and applied to a modified QUASARTM respiratory motion phantom. A novel approach to 3D dosimetry was developed using Gafchromic EBT3 film, allowing the 3D dose distribution delivered to the moving phantom to be reconstructed. Treatments were planned using the recommended margins for one and three fiducial markers and XLTS 2-view, 1-view and 0-view target-tracking modalities. The dose delivery accuracy was analysed by comparing the reconstructed dose distributions to the planned dose distributions using gamma index analysis. Results: For the 3%/2mm gamma criterion, gamma passing rates up to 99.37% were observed for the static deliveries. The 3-fiducial and 1-fiducial-based deliveries exhibited passing rates of 93.74% and 97.82%, respectively, in the absence of target rotation. When target rotation was considered, the passing rate for 1-fiducial tracking degraded to 91.24%. The passing rates observed for XLTS 2-view, 1-view and 0-view target-tracking were 92.78%, 96.22% and 76.08%, respectively. Conclusions: Except for the XLTS 0-view, the dosimetric accuracy of the XLTS was comparable to the FTTS under equivalent treatment conditions. This study gives us further confidence in the CyberKnife XLTS and FTTS systems.
Exploring an urban integrated pluvial flood risk assessment using big data
Authors: Zhang Hui , Li Cheng , Wu Zhifeng , Zhang Qifei
Published: May 2022

Currently, urban pluvial flood risk management and mitigation strongly require integrated flood risk assessment at a fine scale. In this study, we tried to perform integrated pluvial flood risk assessment in the framework of “hazard-exposure-vulnerability” at the grid scale. First, a simplified pluvial flood inundation was utilized to quickly calculate flood depth for hazard information to find the flood depth under different precipitation conditions. Next, spatial analysis based on Geographic Information Science (GIS) was chosen to analyze the entire exposure degree of land use. Then, point of interest (POI) data together with traditional statistical data were analyzed by principal component analysis (PCA) for vulnerability assessment at the grid scale, and spatial overlay analysis was used to obtain the integrated risk assessment. The results showed that as the intensity of heavy rain increased, the level and intensity of hazard and exposure risk increased accordingly and showed obvious spatial agglomeration. The 20-year return period of a rainstorm was an inflection point for the area change of hazard. However, vulnerability had a significant clustering effect, which was obviously distinct from hazard and exposure risk. As the rainstorm intensity increased, the regional area of pluvial flood risk facing two or three risks gradually increased, and its spatial agglomeration effect also gradually increased. It is worth noting that the highest integrated risk area was mainly distributed near both the midstream and the downstream sides of Donghaochong. Our research can provide scientific reference for the mitigation of urban pluvial flood risk, and case reference for other cities to carry out similar research.
Neoadjuvant Chemotherapy with Weekly Cisplatin and Paclitaxel Followed by Chemoradiation for Locally Advanced Cervical Cancer
Authors: Li Jing , Li Ya , Wang Huafeng , Shen Lifei , Wang Qun , Shao Siqi , Shen Yuhong , Xu Haoping , Liu Hua , Cai Rong , Feng Weiwei
Published: May 2022

Background Currently, the standard treatment for locally advanced cervical cancer is concurrent chemoradiation (CCRT). Forty percent of patients present with disease recurrence. This study aims to investigate the feasibility, safety and efficacy of neoadjuvant chemotherapy (NACT) with weekly cisplatin and paclitaxel (TP) followed by CCRT.Methods We are conducting a phase III trial comparing the efficacy and side effects of patients with cervical cancer (FIGO 2018 stage IIB to IVA) who were assigned to four cycles of NACT with cisplatin (40 mg/m2) and paclitaxel (60 mg/m2) weekly followed CCRT or CCRT alone. In this report, we studied the medium-term effect of 50 patients enrolled in the NACT+CCRT arm. The primary endpoints were the response rate post-NACT and 12 weeks post-CCRT evaluated by MR/CT based on RECIST v 1.1 criteria. The secondary endpoints were 3-year OS (overall survival) and PFS (progression-free survival) measured by the Kaplan–Meier method.Results Among 50 patients enrolled in the NACT+CCRT arm, the complete and partial response rates were 10.4% and 68.8%, post-NACT. After treatment completion, the complete response rate was 72.0%, whereas the total response rate (complete and partial response) was 90.0%. After a median follow-up of 28 months, the 3-year OS rate was 83.9%, and the 3-year PFS rate was 73.6%. NACT response was related to superior PFS and OS compared with NACT nonresponse (P<0.01). Late AEs were exiguous, while early AEs mainly included myelosuppression and gastrointestinal AEs.Conclusion This study showed a good response rate achieved by dose-dense weekly cisplatin and paclitaxel followed by standard CCRT. The treatment regimen is feasible, as evidenced by the acceptable toxicity of NACT and by the high compliance with radiotherapy.Trial registration Protocol version number and dateChinese clinical trial registry, ChiCTR1900025327; http://www.chictr.org.cn. Registered 24 August 2019. Retrospectively registered, medresman.org.cn/ChiCTR1900025326The date recruitment began 01-01-2019
Environmental and Socio-economic drivers of child anthropometric failures in selected countries of South Asia
Authors: saif sabeen , Anwar Sofia
Published: May 2022

The pervasiveness of malnutrition among children under five is unacceptably high in South Asia. Assessment of overall burden of malnutrition with summation of Gomez and Waterlow’s three class divisions in Svedberg formulated composite index of anthropometric failure (CIAF) and Nandy’s revised CIAF have overlooked the incidence of overnutrition and their possible connections with other subgroups. This study proposes a new scheme; an extended version of CIAF as developed by Kuiti & Bose (2018), to accurately estimates the prevalence of anthropometric failures. The study also examines the effects of socio-economic and environmental variables on child malnutrition in selected South Asian countries include Pakistan, India and Bangladesh. For empirical analysis, panel cointegration technique is employed by using data for the period of 1990 to 2018. All the variables are stationary at first difference. Fully Modified OLS (FMOLS) method is applied to explore the parameter estimates. The results showed that political stability, prevalence of undernourishment, anemia in children, mother’s education, household size, dependency ratio, air pollution and unimproved sanitation significantly correlated with childhood undernutrition. The findings also testified long-run cointegrating relationship among the variables.
Determinant of under nutrition among under five children in Ambo town during covid 19 pandemic. A community-based cross-sectional study
Authors: Feyisa Beshadu Bedada , Dabu Getu Taresa
Published: May 2022

Background: About 8 to 44% of all child mortality in Africa is associated with undernutrition. To alleviate this problem, it is necessary to determine the magnitude and determinants of undernutrition. However, there is scarce evidence in an urban setting like Ambo town. Therefore, this study assessed the magnitude and factors associated with undernutrition under five children in Ambo town, west Ethiopia.Methods and patients: A community-based cross-sectional study was conducted in Ambo town from March 01 - 30, 2020. A systematic sampling technique was employed to select 363 study participants. Nutritional status indices were generated using ENASMART software. After testing for collinearity, variables with a p-value < 0.25 in binary logistic regression were interred to backward multiple logistic regressions at a level of significance of p < 0.05. Results: This study found 16.00%, 25.30%, and 19.00% of the study participants were underweight, wasted, and stunted respectively. Decisions making on major food purchases, who usually care for the child, the age at which the child starts complimentary food, late introduction of complementary food were positively associated with wasting. Diarrhea, birth weight, child age, age at which the child starts complimentary food, consumption of milk and milk product, and who usually care for the child were significantly associated with underweight. Consumption of milk and milk products, household food security level, and birth weight were independent determinants of stunting. Conclusion: This study identified high prevalence of undernutrition, especially wasting. Child birth weight, age, diarrhea, feeing practice, house hold (HH) food security, Decision making on major food purchase, late introduction of complimentary food were found to be the potential determinants of undernutrition. Thus there should be an effort to improve the nutritional status of children in the study area by focusing on these factors.