bluuebunny/crossref_metadata_2025 huggingface dataset:
Hybrid Detection Method for Multi-Intent Recognition in Air–Ground Communication Text
Authors: Pan Weijun , Wang Zixuan , Wang Zhuang , Wang Yidi , Huang Yuanjing
Published: July 2024

In recent years, the civil aviation industry has actively promoted the automation and intelligence of control processes with the increasing use of various artificial intelligence technologies. Air–ground communication, as the primary means of interaction between controllers and pilots, typically involves one or more intents. Recognizing multiple intents within air–ground communication texts is a critical step in automating and advancing the control process intelligently. Therefore, this study proposes a hybrid detection method for multi-intent recognition in air–ground communication text. This method improves recognition accuracy by using different models for single-intent texts and multi-intent texts. First, the air–ground communication text is divided into two categories using multi-intent detection technology: single-intent text and multi-intent text. Next, for single-intent text, the Enhanced Representation through Knowledge Integration (ERNIE) 3.0 model is used for recognition; while the A Lite Bidirectional Encoder Representations from Transformers (ALBERT)_Sequence-to-Sequence_Attention (ASA) model is proposed for identifying multi-intent texts. Finally, combining the recognition results from the two models yields the final result. Experimental results demonstrate that using the ASA model for multi-intent text recognition achieved an accuracy rate of 97.84%, which is 0.34% higher than the baseline ALBERT model and 0.15% to 0.87% higher than other improved models based on ALBERT and ERNIE 3.0. The single-intent recognition model achieved an accuracy of 96.23% when recognizing single-intent texts, which is at least 2.18% higher than the multi-intent recognition model. The results indicate that employing different models for various types of texts can substantially enhance recognition accuracy.
Characteristics of Grassland Species Diversity and Soil Physicochemical Properties with Elevation Gradient in Burzin Forest Area
Authors: Qian Jiaorong , Ye Mao , Zhang Xi , Li Miaomiao , Chen Weilong , Zeng Guoyan , Che Jing , Lv Yexin
Published: July 2024

In order to explore the changes and interrelationships of grassland plant community species diversity and soil physicochemical properties with elevation gradient, this study takes the grassland in the Burzin forest area of Xinjiang as the research object and analyzes the responses of grassland species diversity, aboveground biomass, and soil physicochemical properties to the changes of elevation gradient within the altitude range of 1000~2200 m in this area. The results of the study show that: (1) The number of species and aboveground biomass reached the highest levels at elevation gradient III and showed a tendency of increasing and then decreasing with elevation. The Margalef and Shannon–Wiener indices were the largest at elevation III, while the Simpson and Alatalo indices were the largest at elevation I. (2) With the change of elevation, the available nitrogen (AN), available phosphorus (AP), soil electric conductivity (SEC), and soil pH showed a trend of increasing and then decreasing, while soil temperature decreased with elevation. Available potassium and soil water content reached their maximum values at elevation I and elevation IV, respectively. (3) The soil conductivity and diversity index were negatively correlated in elevation gradients I to III. In elevation gradient I~III, soil conductivity was positively correlated with the diversity index and aboveground biomass. Available nitrogen had a significant effect on plant diversity and biomass in elevation gradients IV to VI. (4) Aboveground biomass was significantly positively correlated with the Simpson’s index, while the relationship with the Shannon–Wiener index was less significant, and Margalef’s and Alatalo’s indices were not significant. Soil conductivity and pH significantly affected the Margalef and Simpson indices. Available nitrogen was closely related to the aboveground biomass and Margalef and Alatalo indices. Soil moisture content significantly affected Simpson’s index and the aboveground biomass. This study provides a solid theoretical foundation for the conservation and management of grassland plant community ecosystems along the elevation gradient, and has important reference value for study of the impact of environmental change on species diversity and biodiversity conservation.
Glyphosate Hormesis Improves Agronomic Characteristics and Yield of Glyphosate-Resistant Soybean Under Field Conditions
Authors: Krenchinski Fábio Henrique , Pereira Vinicius Gabriel Canepelle , Giovanelli Bruno Flaibam , Cesco Victor José Salomão , Alcántara-de la Cruz Ricardo , Velini Edivaldo D. , Carbonari Caio A.
Published: July 2024

Brazil, the world’s largest soybean producer, owes its success to the cultivation of glyphosate-resistant (GR) cultivars. However, the soybean yields lag behind those obtained in areas managed for high productivity. Glyphosate-induced hormesis holds promise for increasing crop yields, but the potential evolution of resistance in certain weed species poses a challenge to foliar applications under field conditions. This study assessed the effects of a hormesis-inducing glyphosate dose [90 g acid equivalent (ae) ha−1] on the agronomic characteristics and yield of four GR soybean cultivars. The evaluation was conducted in field settings across various Brazilian locations, considering foliar, seed, and seed + foliar treatments. The results showed variations in dry mass, root nodules, nutrient composition, plant height, pods, and yield, primarily influenced by environmental conditions, soil quality, and, ultimately, the interaction between GR cultivars and treatments. Total dry mass consistently increased with glyphosate, with seed and seed + foliar treatments showing the most substantial increases (7–21%). All three treatments increased nodulation by up to 36% across locations and cultivars, with seed + foliar treatment causing notable increases in nodule dry mass (up to 56%), followed by seed treatment (41%). Nutrient composition, especially for N, P, Br, and Fe, displayed location-dependent variations. Plant height varied among locations and cultivars, with minimal differences between treatments. Glyphosate treatments increased pod numbers (10 to 35%) and yields (11 to 42%) of soybean in seed and seed + foliar treatments. The findings highlight the potential of glyphosate hormesis as a viable tool for improving yields of GR soybean cultivars at the field level. However, the extent of benefits depends on the agronomic conditions of location, choice of cultivars, and herbicide application method.
Segmentation and Coverage Measurement of Maize Canopy Images for Variable-Rate Fertilization Using the MCAC-Unet Model
Authors: Gong Hailiang , Xiao Litong , Wang Xi
Published: July 2024

Excessive fertilizer use has led to environmental pollution and reduced crop yields, underscoring the importance of research into variable-rate fertilization (VRF) based on digital image technology in precision agriculture. Current methods, which rely on spectral sensors for monitoring and prescription mapping, face significant technical challenges, high costs, and operational complexities, limiting their widespread adoption. This study presents an automated, intelligent, and precise approach to maize canopy image segmentation using the multi-scale attention and Unet model to enhance VRF decision making, reduce fertilization costs, and improve accuracy. A dataset of maize canopy images under various lighting and growth conditions was collected and subjected to data augmentation and normalization preprocessing. The MCAC-Unet model, built upon the MobilenetV3 backbone network and integrating the convolutional block attention module (CBAM), atrous spatial pyramid pooling (ASPP) multi-scale feature fusion, and content-aware reassembly of features (CARAFE) adaptive upsampling modules, achieved a mean intersection over union (mIOU) of 87.51% and a mean pixel accuracy (mPA) of 93.85% in maize canopy image segmentation. Coverage measurements at a height of 1.1 m indicated a relative error ranging from 3.12% to 6.82%, averaging 4.43%, with a determination coefficient of 0.911, meeting practical requirements. The proposed model and measurement system effectively address the challenges in maize canopy segmentation and coverage assessment, providing robust support for crop monitoring and VRF decision making in complex environments.
Clostridium butyricum Probiotic Feed Additive: Modulation of Sow Milk Metabolomics and Mitigation of Pre-Weaning Piglet Diarrhea
Authors: Ruampatana Jakavat , Suwimonteerabutr Junpen , Homyog Kunaporn , Mekboonsonglarp Wanwimon , Kanjanavaikoon Korntip , der Veken Wouter Van , Poonyachoti Sutthasinee , Feyera Takele , Settachaimongkon Sarn , Nuntapaitoon Morakot
Published: July 2024

The present study aimed to investigate the impact of Clostridium butyricum probiotic feed additive on sow and piglet performances, together with alterations in the lipidomic and metabolomic profiles of sow milk. Sixty-four Landrace × Yorkshire crossbred sows and 794 piglets were included. Sows were divided into two groups; i.e., (i) conventional gestation diet (control; n = 35) and (ii) conventional diet added with 10 g/sow/day of probiotic C. butyricum spores (treatment; n = 29) from one week before the estimated farrowing day until weaning (29.6 ± 4.8 days). The sow and piglet performances and incidence of piglet diarrhea were recorded. Changes in gross chemical composition, fatty acid and non-volatile polar metabolite profiles of sow colostrum, transient milk and mature milk were evaluated. The results showed that relative backfat loss in the treatment group (−2.3%) was significantly lower than in control group (11.6%), especially in primiparous sows (p = 0.019). The application of C. butyricum probiotics in sows significantly reduced the incidence of diarrhea in piglets (p < 0.001) but no other effect on piglet performance was found. Lipidomic and metabolomic analyses revealed variations in sow colostrum and milk biomolecular profiles, with indicative compounds significantly altered by feeding with the C. butyricum probiotics. In conclusion, the use of C. butyricum probiotics in sows may improve sow body condition and reduce diarrhea incidence in piglets, with underlying changes in milk composition that warrant further investigation. These findings support the potential of C. butyricum as a beneficial feed additive in swine production.
Classification and Multi-Functional Use of Bacteriocins in Health, Biotechnology, and Food Industry
Authors: Solis-Balandra Miguel Angel , Sanchez-Salas Jose Luis
Published: July 2024

Bacteriocins is the name given to products of the secondary metabolism of many bacterial genera that must display antimicrobial activity. Although there are several bacteriocins described today, it has not been possible to reach a consensus on the method of classification for these biomolecules. In addition, many of them are not yet authorized for therapeutic use against multi-drug-resistant microorganisms due to possible toxic effects. However, recent research has achieved considerable progress in the understanding, classification, and elucidation of their mechanisms of action against microorganisms, which are of medical and biotechnological interest. Therefore, in more current times, protocols are already being conducted for their optimal use, in the hopes of solving multiple health and food conservation problems. This review aims to synthetize the information available nowadays regarding bacteriocins, and their classification, while also providing an insight into the future possibilities of their usage for both the pharmaceutical, food, and biotechnological industry.
Placental Bioenergetics and Antioxidant Homeostasis in Maternal Obesity and Gestational Diabetes
Authors: Mandò Chiara , Castiglioni Sara , Novielli Chiara , Anelli Gaia Maria , Serati Anaïs , Parisi Francesca , Lubrano Chiara , Zocchi Monica , Ottria Roberta , Giovarelli Matteo
Published: July 2024

Maternal obesity has been associated with short- and long-term risks of pregnancy-perinatal adverse events, possibly due to alterations of placental mitochondrial bioenergetics. However, several detrimental mechanisms occurring in the placentas of women with obesity still need to be clarified. Here, we analyzed placental mitochondrial features and oxidative environment of 46 pregnancies in relation to pre-pregnancy BMI. Seventeen Caucasian normal-weight (NW) and twenty-nine women who were obese (OB) were enrolled. The protein expression of mitochondrial CypD and electron transfer chain complexes (C) I–V were measured, as well as ATP production and oxygen consumption rates (OCRs). The protein levels of the pro/anti-oxidant enzymes TXNIP, SOD2, and PON2 were also analyzed. Despite no differences in CypD expression, OCRs were significantly lower in OB vs. NW women. Accordingly, ATP synthase (CV) levels and ATP content were decreased in OB women, positively correlating with placental efficiency, suggesting a link between ATP deficiency and placental dysfunction. SOD2 expression negatively correlated with maternal BMI, indicating a possible impairment of antioxidant defenses with increasing BMI. These changes were worsened in 10 OB women presenting with gestational diabetes mellitus. Overall, these results suggest alterations of placental bioenergetics in pregnancies of women with obesity, possibly leading to placental dysfunction and altered fetal development and programming.
Antioxidant and Neuroprotective Effects of Seed Oils from Trichosanthes kirilowii and T. laceribractea in Caenorhabditis elegans: A Comparative Analysis and Mechanism Study
Authors: Wang Wenqian , Li Shan , Zhu Yunguo , Cui Xianghuan , Sheng Zhejin , Wang Hongbing , Cheng Zhou
Published: July 2024

Excess reactive oxygen species (ROS) can accelerate amyloid β (Aβ) aggregation and tau protein hyperphosphorylation in neuron cells, which further leads to neurodegenerative diseases such as Alzheimer’s disease (AD). Therefore, there is an urgent need to find natural and safe antioxidants for preventing or treating such neurodegenerative diseases. The seeds of Trichosanthes kirilowii Maxim and T. laceribractea Hayata have long been used for medicinal and edible purposes in China. However, the antioxidant and neuroprotective activities and underlying mechanisms of their seed oils still remain unclear. Herein, we examine the antioxidant and neuroprotective effects of seed oils extracted from different germplasms, T. kirilowii (YNHH and SDJN) and T. laceribractea (ZJQT and SXHZ), on ROS levels and neuroprotective activities in C. elegans. The results demonstrated that the seed oils significantly reduced the ROS levels in C. elegans by 17.03–42.74%, with T. kirilowii (YNHH and SDJN) exhibiting significantly stronger ROS scavenging abilities than T. laceribractea (ZJQT and SXHZ). The seed oils from T. kirilowii (YNHH and SDJN) alleviated the production and aggregation of Aβ and the phosphorylation and polymerization of tau, suggesting a potential neuroprotective role. Conversely, seed oils from T. laceribractea (ZJQT and SXHZ) show minimal neuroprotective effects in C. elegans. These differential outcomes might stem from distinct mechanisms underlying antioxidant and neuroprotective effects, with the ctl-2 gene implicated as pivotal in mediating the significant neuroprotective effects of seed oils from T. kirilowii (YNHH and SDJN). Our findings have provided valuable insights into the antioxidant and neuroprotective properties of T. kirilowii seed oils, paving the way for further research aimed at elucidating the underlying mechanisms and exploring their potential therapeutic applications in combating neurodegenerative diseases.
Evaluation of Hydrogen Generation with Hybrid Renewable Energy Sources
Authors: Ramadan A. , Gabbar Hossam A.
Published: July 2024

Generating hydrogen by electrolysis in an alkaline system with a green power source consisting of wind turbines (WTs) and photovoltaic (PV) power is a promising and sustainable way to produce clean hydrogen to reduce greenhouse gas emissions. This study utilized TRNSYS 16 software to perform a dynamic simulation of a hydrogen system. TRNSYS, which stands for Transient System Simulation Program, is a software package designed for simulating the dynamic behaviour of thermal and electrical energy systems. It is widely used to analyze and optimize the performance of various energy systems. This system incorporated a PV power source and a WT for electricity generation, along with an electrolyzer for hydrogen production. The analysis was carried out to evaluate variable weather conditions, specifically wind speed, solar radiation, and temperature. These factors have a direct impact on the system’s performance, influencing the available power as a consequential outcome. The results reveal that, given the specific climate conditions in the Markham zone, Toronto, the integrated renewable system is capable of consistently providing electricity and meeting the load demand throughout the entire year. However, it is noteworthy that on cold days when solar radiation is limited, the WT emerges as the most effective and efficient power source. The analysis also indicates that the system reliably supplies enough energy to meet the laboratory’s load demand. Moreover, the system’s performance is particularly impressive with the WT as the power source, as it can generate a maximum of 9.03 kg of hydrogen per month. In contrast, the PV power source yields only 0.58 kg H2. Additionally, the cost per kilogram of hydrogen (kg H2) is considerably lower when the WT is used, at USD 0.55/kg H2, while it rises to USD 1.5/kg H2 when PV is the power source. These findings underscore the significance of using the most suitable power source, such as a WT, in specific climatic conditions and regions in terms of both performance and cost-effectiveness.
Effects of Rowing on Cardiac Function in Breast Cancer Survivors: Sliding Seat Rowing vs. Fixed Seat Rowing
Authors: Gavala-González Juan , Real-Pérez Mateo , Gamboa-González Juan , Fernández-García José Carlos
Published: July 2024

This longitudinal study aimed to analyze the effects of a team rowing-based training program on physical fitness and anthropometric parameters in female breast cancer survivors (n = 40; 56.78 ± 6.38 years). Participants were divided into two groups: one rowed in fixed seat rowing (FSR) boats (n = 20; 56.35 ± 4.89 years) and the other in sliding seat rowing (SSR) boats (n = 20; 57.20 ± 7.7 years). Both groups engaged in two 75-min sessions per week for 24 weeks. Significant improvements were observed in both groups in resting heart rate (FSR: −10.65 bpm; SSR: −8.45 bpm), heart rate at the beginning of the 6-min walk test (6 MWT) (FSR: −10.7 bpm; SSR: −11.25 bpm), and heart rate at the end of the test (FSR: −13.85 bpm; SSR: −20.35 bpm). Blood pressure improved significantly in both diastolic blood pressure (FSR: −12.35 mmHg; SSR: −19.25 mmHg) and systolic blood pressure (FSR: −13 mmHg; SSR: −16.95 mmHg). Additionally, both groups increased the distance covered in the 6 MWT (FSR: +63.05 m; SSR: +93.65 m). These results suggest that a rowing training program is a viable and safe activity for female breast cancer survivors, improving cardiac function, blood pressure, and cardiorespiratory capacity, particularly in sliding seat boats.
Smart Low-Cost Control System for Fish Farm Facilities
Authors: Parra Lorena , Sendra Sandra , Garcia Laura , Lloret Jaime
Published: July 2024

Projections indicate aquaculture will produce 106 million tonnes of fish by 2030, emphasizing the need for efficient and sustainable practices. New technologies can provide a valuable tool for adequate fish farm management. The aim of this paper is to explore the factors affecting fish well-being, the design of control systems for aquaculture, and the proposal of a smart system based on algorithms to improve efficiency and sustainability. First, we identify the domains affecting fish well-being: the production domain, abiotic domain, biotic domain, and control systems domain. Then, we evaluate the interactions between elements present in each domain to evaluate the key aspects to be monitored. This is conducted for two types of fish farming facilities: cages in the sea and recirculating aquaculture systems. A total of 86 factors have been identified, of which 17 and 32 were selected to be included in monitoring systems for sea cages and recirculating aquaculture systems. Then, a series of algorithms are proposed to optimize fish farming management. We have included predefined control algorithms, energy-efficient algorithms, fault tolerance algorithms, data management algorithms, and a smart control algorithm. The smart control algorithms have been proposed considering all the aforementioned factors, and two scenarios are simulated to evaluate the benefits of the smart control algorithm. In the simulated case, the turbidity when the control algorithm is used represents 12.5% of the turbidity when not used. Their use resulted in a 35% reduction in the energy consumption of the aerator system when the smart control was implemented.
Comparative Study of the Effects of Conventional, Waste, and Alternative Materials on the Geomechanical Properties of Clayey Soil in the Chemical Soil Stabilisation Technique
Authors: Zlatanović Elefterija , Marinković Nemanja , Bonić Zoran , Romić Nikola , Djorić-Veljković Snežana , Cvetković Dušan , Djordjević Dragan
Published: July 2024

This paper presents an extensive comparative analysis of the experimental results of chemical stabilisation of clayey soil in laboratory conditions by comparing the effects of adding conventional stabilisers (lime, cement binder), stabilisers that can be considered as waste material (fly ash, rock flour), as well as alternative chloride-based materials (ferric chloride, calcium chloride, potassium chloride) on the geomechanical properties of the soil. With the aim of determining the stabiliser optimal content in the mixture with the soil, in the first part of the research, the effects of stabilisation of clayey soil of medium plasticity using the considered stabilisers with different percentage share on the change in uniaxial compressive strength (UCS) and pH value of the soil at different time intervals after the treatment were analysed. In the second part of the research, additional tests were conducted on soil samples with optimal content for each of the considered stabilisers by monitoring changes in the physical and mechanical properties of the soil. These include Atterberg’s limits (liquid limit and plasticity limit), modulus of compressibility in the oedometer, California bearing ratio (CBR), and swelling potential at different time intervals after the chemical treatment to determine the durability of stabilisation effects. The results of the conducted research reveal that each of the conventional, waste, and alternative materials considered as chemical stabilisers contributes to the improvement of the geomechanical properties of the clayey soil, primarily in terms of increasing the bearing capacity and reducing the swelling of the treated soil.
Study on the Three-Dimensional Behavior of Blasting Considering Non-Uniform In-Situ Stresses Distributed along the Blasthole Axis
Authors: Wang Gongyuan , Bai Jianbiao , Meng Ningkang , Zhao Xiangqian
Published: July 2024

For roof-cutting by blasting in the gob-side entry under an overhanging hard roof, studies on the impacts of in-situ stresses on the propagation of blast-induced cracks have typically focused on uniform stresses but ignored the effects of non-uniform in-situ stresses (NIS) distributed along the blasthole axis. Therefore, the distribution patterns of hoop stress and rock damage caused by NIS distributed along the blasthole axis were investigated using numerical modeling and theoretical analysis. The results illustrate that with the rising NIS for the cross section along the blasthole axis, the peak values of hoop compressive stress at the same distance from the blasthole’s center gradually increase, resulting in a nonlinear attenuation trend in the damage range of the rock. Consequently, the spacing between blastholes should be determined based on the average length of the primary cracks under the maximum confining pressure. Additionally, for the cross section perpendicular to the blasthole axis, as the lateral pressure coefficient increases from 0.25 to 2, the damage range in the vertical direction significantly decreases. This results in varying extents of blast-induced cracks within the coal pillar, providing a reference for the design of shallow-borehole crack filling.
Study on Formation Mechanism of Advance Grouting Curtain in Ore-Rock Contact Zone in Water-Rich Roadway
Authors: Kong Bei , Han Lijun , Zheng Jiongze
Published: July 2024

During tunnel development in metal mines, there are situations where a zone of contact between the ore and the surrounding rock is reached. Nevertheless, there is a notable disparity in the mechanical characteristics between the ore and the surrounding rock, leading to a specific response of grouting in the contact area between the ore and rock. This response differs from the typical diffusion and curtain formation effects observed when using grouting slurry. This study investigates the effects of grouting curtain creation when implementing highly advanced curtain grouting in a water-rich highway, utilizing the engineering conditions of Zhongjiu Iron Mine as a reference. At first, Darcy’s law and the Navier-Stokes equation are used to control the flow of fluid in the area where the ore-rock meets the rock around it. COMSOL, a multi-physical field coupled analysis software, is employed for the numerical simulation of slurry plane diffusion, single-hole, and group-hole curtain grouting. Two optimization strategies for group-hole grouting parameters are subsequently suggested and proven using numerical simulation. Finally, the project implements the research to assess the influence of curtain grouting by employing the water influx of the exploratory apertures as the standard of comparison before and after grouting; the results demonstrate that the slurry forms a highly efficient grouting curtain, effectively impeding water infiltration. The findings indicate that slurry diffusion in the contact zone between the ore and rock follows a spherical motion pattern, resulting in a considerable decrease in the flow rate compared to the previous stage. The force of gravity visibly affects the spreading of the slurry in the area where the ore and rock come into contact, causing the slurry to mostly spread downwards. This inclination intensifies as the rate of grouting is elevated. To successfully address the inadequate distribution of the slurry, one can either increase the rate at which grouting is performed or decrease the distance between the grouting holes.
Sensitivity Analysis and Filtering of Machinable Parts Using Density-Based Topology Optimization
Authors: Vadillo Morillas Abraham , Meneses Alonso Jesús , Bustos Caballero Alejandro , Castejón Sisamón Cristina
Published: July 2024

Topology optimization has become a popular tool for designing optimal shapes while meeting specific objectives and restrictions. However, the resulting shape from the optimization process may not be easy to manufacture using typical methods like machining and may require interpretation and validation. Additionally, the final shape depends on chosen parameters. In this study, we conduct a sensitivity analysis of the main parameters involved in 3D topology optimization—penalization and filter radius—focusing on the density-based method. We analyze the features and characteristics of the results, concluding that a machinable and low interpretable part is not an attainable result in by-default topology optimization. Therefore, we propose a new method for obtaining more manufacturable and easily interpretable parts. The main goal is to assist designers in choosing appropriate parameters and understanding what to consider when seeking optimized shapes, giving them a new plug-and-play tool for manufacturable designs. We chose the density-based topology optimization method due to its popularity in commercial packages, and the conclusions may directly influence designers’ work. Finally, we verify the study results through different cases to ensure the validity of the conclusions.
Longitudinal Nonlinear Equivalent Continuous Model for Shield Tunnel under Coupling of Longitudinal Axial Force and Bending Moment
Authors: Guo Xiangyu , Xu Zhe , Cai Qipeng , Chen Changjian
Published: July 2024

The longitudinal equivalent continuous model generally only studies the stiffness of shield tunnels under longitudinal bending moments, considering it a constant. However, in actual engineering, shield tunnels are exposed to complex environments where seismic events, uneven settlement, etc., may cause simultaneous axial forces and bending moments between segmental rings, necessitating consideration of the longitudinal stiffness of shield tunnels under coupled axial force and bending moment effects. Therefore, based on the influence of different axial forces and bending moments on the separation effect between segmental rings, this study establishes a longitudinal nonlinear equivalent continuous model. Using Guangzhou Metro Line 18 as a case study background, a numerical model of segment ring-bolt is established for comparative analysis. The results show that the contact states between segmental rings can be classified into three modes: completely separated, completely in contact, and partially in contact. Longitudinal bending stiffness remains constant in modes 1 and 2 but decreases with decreasing e in mode 3. The numerically simulated φ−e curves are consistent with the theoretical results. At the special point e0, the numerical simulation result is −57.27° compared to the theoretical result of −59.66°; at point eφ0 (−0.3036), the numerical simulation result is close to 0°. The longitudinal bending stiffness curve shows an overall decreasing trend. When e≤−2r, which corresponds to mode 2, the longitudinal bending stiffness remains constant at πr3Ect. As the longitudinal axial pressure decreases, the longitudinal bending stiffness continues to decrease when −2r≤e≤eφ0. When the longitudinal axial pressure decreases to 0, then the tensile force gradually increases (eφ0≤e≤2r). −2r≤e≤2r belongs to mode 3, and the equivalent bending stiffness is 2(1+sinφ)r3EctA4′−A3′er. As tension continues to increase, when e≥2r, the stiffness no longer decreases, and the longitudinal bending stiffness is πr3Ectu+1, which belongs to mode 1. The overall trend of the tensile and compressive stiffness curves is an inverse proportional function, with the middle mutation point at φ=0, i.e., eφ0=−4u(2+u)πr≈−0.3036. The findings of this study can provide a basis for the rational calculation of longitudinal forces in shield tunnels in engineering applications.
The Enhancement Discharge Performance by Zinc-Coated Aluminum Anode for Aluminum–Air Battery in Sodium Chloride Solution
Authors: Sitanggang Ruly Bayu , Nur’aini Syarifa , Susanto Susanto , Widiyastuti Widiyastuti , Setyawan Heru
Published: July 2024

The main drawback of seawater batteries that use the aluminum (Al)–air system is their susceptibility to anode self-corrosion during the oxygen evolution reaction, which, in turn, affects their discharge performance. This study consist of an electrochemical investigation of pure Al, 6061 Al alloy, and both types coated with zinc as an anode in a 3.5% sodium chloride (NaCl) electrolyte. The electrolyte solution used for the deposition of zinc metal contained citrate, with and without EDTA as a complexing agent. Subsequently, the performance of the anode was tested in a seawater battery, using a carbon@MnO2 cathode and a 3.5% NaCl electrolyte. The performance of Al–air batteries has been significantly enhanced by applying a process of electrodepositing zinc (Zn) with a citrate deposition electrolyte solution in both pure aluminum and alloy 6061. The performance of the battery was further enhanced by adding EDTA as a chelating agent to the citrate-based electrolyte solution. The Al–air battery with aluminum alloy 6061 with Zn electrodeposition with an additional EDTA as the anode, carbon@MnO2 as the cathode, and NaCl 3.5% solution as the electrolyte has the highest battery performance, with a specific discharge capacity reaching 414.561 mAh.g−1 and a specific energy density reaching 0.255 mWh.g−1, with stable voltage at 0.55 V for 207 h.
ELFNet: An Effective Electricity Load Forecasting Model Based on a Deep Convolutional Neural Network with a Double-Attention Mechanism
Authors: Zhao Pei , Ling Guang , Song Xiangxiang
Published: July 2024

Forecasting energy demand is critical to ensure the steady operation of the power system. However, present approaches to estimating power load are still unsatisfactory in terms of accuracy, precision, and efficiency. In this paper, we propose a novel method, named ELFNet, for estimating short-term electricity consumption, based on the deep convolutional neural network model with a double-attention mechanism. The Gramian Angular Field method is utilized to convert electrical load time series into 2D image data for input into the proposed model. The prediction accuracy is greatly improved through the use of a convolutional neural network to extract the intrinsic characteristics from the input data, along with channel attention and spatial attention modules, to enhance the crucial features and suppress the irrelevant ones. The present ELFNet method is compared to several classic deep learning networks across different prediction horizons using publicly available data on real power demands from the Belgian grid firm Elia. The results show that the suggested approach is competitive and effective for short-term power load forecasting.
Chronological and Archaeometric Evaluation of Bricks from Archaeological Sites of Upper Assam, Northeast India: Estimation of the Firing Temperature and Civilization History
Authors: Saikia Raktim Ranjan , Taye Chaitra Dhar , Amin Nurul , Konwar Sorat , Panzeri Laura , Galli Anna
Published: July 2024

This study aimed to uncover the chronology and production technologies of ancient bricks unearthed from various locations in Upper Assam, Northeast India. To achieve this goal, complementary spectroscopic techniques such as Fourier Transform Infrared Spectroscopy (FTIR), X-ray Diffraction (XRD), Scanning Electron Microscope (SEM) coupled with Energy Dispersive Spectrometer (EDS), as well as Thermoluminescence (TL) and Optically Stimulated Luminescence (OSL/IRSL) dating, were applied. FTIR and XRD analyses revealed the presence of quartz, feldspar (microcline, orthoclase, albite), kaolinite, chlorite, cerussite, palygorskite, magnetite, hematite, and organic carbon. The mineralogical composition indicates two distinct groups with firing temperatures below 650 °C and above ~800 °C. These two groups could be the first indication of the presence of two civilizations or at least two different production technologies involving different firing temperatures and kiln atmospheric conditions. Further, the SEM-EDS study suggests that both calcareous and non-calcareous clays were used in brick making, which have low and high refractory properties, respectively. The internal morphology of the samples shows the existence of micropores and microfractures, indicating the influence of higher-temperature firing. Absolute dating techniques associate the two brick groups with different age ranges: a firing temperature above ~800 °C indicates a superior technology corresponding to a production period between the 7th and 10th centuries CE. In contrast, a temperature below 650 °C indicates a technologically less advanced group of people, with the age group dated between the 11th and 14th centuries CE.
Development and Characterization of Hybrid Burgers Made from Pork and Multi-Ingredient Plant Mixtures and Protected with Lactic Acid Bacteria
Authors: Dasiewicz Krzysztof , Szymanska Iwona , Opat Dominika , Hac-Szymanczuk Elzbieta
Published: July 2024

Hybrid (meat–plant) products can be a sustainable response to the increased interest in flexitarianism. Their development requires designing appropriate composition and functional properties and ensuring microbiological safety. This study aimed to determine the influence of using various multi-ingredient plant mixtures and pork in different proportions and two recipe variants on the characteristics of baked burgers. Additionally, the impact of lactic acid bacteria (LAB) application on the microbiological quality of raw hybrid/plant burgers was assessed. All products were analyzed in terms of basic chemical composition (NIR spectroscopy) and physicochemical and textural properties (instrumental methods). The raw plant and hybrid burgers met the microbiological requirements. The baked burgers did not significantly differ in terms of their chemical composition, except for the fiber found in plant/hybrid samples. Moreover, the reformulation of burgers had no effect on their cooking yield or water activity. As the content of plant parts increased, the baked burgers were darker (lower L*) and had a more tender texture (lower shear force and penetration force). Overall, the multi-ingredient plant mixtures showed great potential in the development of high-quality hybrid burgers. However, the texture formed can, importantly, determine final consumer acceptance. Therefore, research should be continued, especially in terms of comprehensive textural and sensory analyses.
Knowledge and Practice in Cochlear Re-Implantation in the UK: A Survey for Audiologists
Authors: Ayas Muhammed , Parker Rosalyn , Muir David , Muzaffar Jameel
Published: July 2024

Background: Cochlear implantation (CI) has proven to be a highly effective method for rehabilitating individuals with severe to profound hearing loss. However, challenges persist, particularly in cases where CI failure necessitates re-implantation. This study aims to address the gap in understanding the knowledge and practices of audiologists in the UK regarding cochlear re-implantation through a comprehensive questionnaire survey. Methods: A bespoke questionnaire was distributed to audiologists working with CI across the UK. The survey, which included multiple-choice items, open-text responses, and visual analogue scales, was made accessible via an online link shared through professional bodies, email groups, and social media platforms. Results: The survey received 27 responses, predominantly from female audiologists (71.4%), with significant representation from London (28.6%) and the East of England (21.4%). A majority of respondents had over 16 years of CI experience (35.7%) and held a master’s degree (60.7%). Key reasons for CI re-implantation included electrode failure (82.1%) and hermetic seal failure (60.7%). While respondents showed strong confidence in counselling (88.8%) and managing re-implanted devices (84.6%), there was a noted variation in opinions regarding the need for additional training in intraoperative measures. Conclusion: This survey highlights the current practices and training needs of UK audiologists in CI re-implantation. This underscores the importance of targeted training to fill knowledge gaps and improve clinical care during CI re-implantation, ultimately enhancing outcomes for both audiologists and CI recipients.
Cimicifugoside H-2 as an Inhibitor of IKK1/Alpha: A Molecular Docking and Dynamic Simulation Study
Authors: Aboul Hosn Shahd , El Ahmadieh Christina , Thoumi Sergio , Sinno Aia , Al Khoury Charbel
Published: July 2024

One of the most challenging issues scientists face is finding a suitable non-invasive treatment for cancer, as it is widespread around the world. The efficacy of phytochemicals that target oncogenic pathways appears to be quite promising and has gained attention over the past few years. We investigated the effect of docking phytochemicals isolated from the rhizomes of the Cimicifuga foetida plant on different domains of the IκB kinase alpha (IKK1/alpha) protein. The Cimicifugoside H-2 phytochemical registered a high docking score on the activation loop of IKK1/alpha amongst the other phytochemicals compared to the positive control. The interaction of the protein with Cimicifugoside H-2 was mostly stabilized by hydrogen bonds and hydrophobic interactions. A dynamic simulation was then performed with the Cimicifugoside H-2 phytochemical on the activation loop of IKK1/alpha, revealing that Cimicifugoside H-2 is a possible inhibitor of this protein. The pharmacokinetic properties of the drug were also examined to assess the safety of administering the drug. Therefore, in this in silico study, we discovered that the Cimicifugoside H-2 phytochemical inhibits the actively mutated conformation of IKK1/alpha, potentially suppressing the nuclear factor kappa light chain enhancer of activated B cells (NF-κB) pathway.
Nocturnal Glucose Profile According to Timing of Dinner Rapid Insulin and Basal and Rapid Insulin Type: An Insulclock® Connected Insulin Cap-Based Real-World Study
Authors: Gómez-Peralta Fernando , Valledor Xoan , Abreu Cristina , Fernández-Rubio Elsa , Cotovad Laura , Pujante Pedro , Azriel Sharona , Pérez-González Jesús , Vallejo Alba , Ruiz-Valdepeñas Luis , Corcoy Rosa
Published: July 2024

Background: A study to assess the glucose levels of people with type 1 diabetes (T1D) overnight, based on the insulin type and timing. Methods: A real-world, retrospective study of T1D, using multiple daily insulin injections. Continuous glucose monitoring and insulin injection data were collected for ten hours after dinner using the Insulclock® connected cap. Meal events were identified using the ROC detection methodology. The timing of the rapid insulin, second injections, and the type of insulin analogs used, were evaluated. Results: The nocturnal profiles (n = 775, 49 subjects) were analyzed. A higher glucose AUC of over 180 mg/dL was observed in subjects with delayed injections (number; %; mg/dL × h): −45–15 min (n = 136; 17.5%, 175.9 ± 271.0); −15–0 min (n = 231; 29.8%, 164.0 ± 2 37.1); 0 + 45 min (n = 408; 52.6%, 203.6 ± 260.9), (p = 0.049). The use of ultrarapid insulin (FiAsp®) (URI) vs. rapid insulin (RI) analogs was associated with less hypoglycemia events (7.1 vs. 13.6%; p = 0.005) and TBR70 (1.7 ± 6.9 vs. 4.6 ± 13.9%; p = 0.003). Users of glargine U300 vs. degludec had a higher TIR (70.7 vs. 58.5%) (adjusted R-squared: 0.22, p < 0.001). The use of a correction injection (n = 144, 18.6%) was associated with a higher number of hypoglycemia events (18.1 vs. 9.5%; p = 0.003), TBR70 (5.5 ± 14.2 vs. 3.0 ± 11.1%; p = 0.003), a glucose AUC of over 180 mg/dL (226.1 ± 257.8 vs. 178.0 ± 255.3 mg/dL × h; p = 0.001), and a lower TIR (56.0 ± 27.4 vs. 62.7 ± 29.6 mg/dL × h; p = 0.004). Conclusion: The dinner rapid insulin timing, insulin type, and the use of correction injections affect the nocturnal glucose profile in T1D.
Aptamer Screening: Current Methods and Future Trend towards Non-SELEX Approach
Authors: Fang Zhihui , Feng Xiaorui , Tang Fan , Jiang Han , Han Shuyuan , Tao Ran , Lu Chenze
Published: July 2024

Aptamers are nucleic acid sequences that specifically bind with target molecules and are vital to applications such as biosensing, drug development, disease diagnostics, etc. The traditional selection procedure of aptamers is based on the Systematic Evolution of Ligands by an Exponential Enrichment (SELEX) process, which relies on repeating cycles of screening and amplification. With the rapid development of aptamer applications, RNA and XNA aptamers draw more attention than before. But their selection is troublesome due to the necessary reverse transcription and transcription process (RNA) or low efficiency and accuracy of enzymes for amplification (XNA). In light of this, we review the recent advances in aptamer selection methods and give an outlook on future development in a non-SELEX approach, which simplifies the procedure and reduces the experimental costs. We first provide an overview of the traditional SELEX methods mostly designed for screening DNA aptamers to introduce the common tools and methods. Then a section on the current screening methods for RNA and XNA is prepared to demonstrate the efforts put into screening these aptamers and the current difficulties. We further predict that the future trend of aptamer selection lies in non-SELEX methods that do not require nucleic acid amplification. We divide non-SELEX methods into an immobilized format and non-immobilized format and discuss how high-resolution partitioning methods could facilitate the further improvement of selection efficiency and accuracy.
The Mediating Role of Interoceptive Sensitivity in the Relationship between Physical Activity and Depression Symptoms in College Students
Authors: Sun Qian , Shen Xiaona , Qi Meiling , Suliman Muhammad , Tian Siyu
Published: July 2024

A substantial body of evidence indicates that neurological, psychological, and behavioral health issues are profoundly linked to interoceptive sensitivity. The present study aimed to identify the effects of interoceptive sensitivity on the relationship between physical activity and symptoms of depression in Chinese college students. This study employed a cross-sectional design using convenience sampling. An online self-reported survey was distributed to college students in China. The participants’ interoceptive sensitivity, physical activity levels, and depressive symptoms were measured using the MAIA-2, IPAQ-SF, and PHQ-9, respectively. The mediating effect was tested via regression analysis and a parallel mediation model, with bootstrap confidence intervals for indirect effects. The results showed a significant negative correlation between physical activity and depression. A significant positive correlation was observed between physical activity and seven dimensions of interoceptive sensitivity. Conversely, interoceptive sensitivity exhibited a negative correlation with depression. The bootstrap mediation analysis showed that the “not distracting” and “trusting” dimensions of interoceptive sensitivity had significant indirect effects on the relationship between physical activity and depression, suggesting that physical activity might reduce depressive symptoms via these two interoceptive sensitivity dimensions. The findings suggest that interoceptive sensitivity should be integrated into therapeutic interventions, such as physical activity interventions, in the treatment of mental illnesses, particularly depression. Increasing physical activity levels, with a specific focus on enhancing interoceptive modulation, appears to be a promising approach for addressing depression in college students.