bluuebunny/crossref_metadata_2025 huggingface dataset:
Molecular genetic determinants of virulence of Streptococcus agalactiae isolated from pregnant women and newborns in St. Petersburg and the Leningrad region in 2010–2023
Authors: Shalepo Kira Shalepo , Khusnutdinova Tatiana A. , Budilovskaya Olga V. , Krysanova Anna A. , Sapozhnikov Kirill V. , Savicheva Alevtina M. , Kogan Igor Yu.
Published: May 2024

Introduction. Colonization of the reproductive organs of pregnant women with group B streptococci (GBS; Streptococcus agalactiae) can lead to severe perinatal and neonatal pathology. In modern conditions, aside from the prevention of antenatal infection of the fetus during childbirth using antibacterial drugs, vaccination is also necessary. In this regard, surveillance of GBS genotypes is an important task.
Objective. To determine the molecular genetic determinants of virulence of Streptococcus agalactiae isolated from pregnant women and newborns, and to monitor the distribution of capsular polysaccharides types and pili profiles in GBS clinical isolates.
Materials and methods. The study used clinical isolates of GBS (n = 420) isolated from pregnant women and newborns in 2010–2023.The bacteriological method was used for isolation of S. agalactiae. PCR method was used to determine the types of capsular polysaccharides, pili, and whether the strains belonged to the hypervirulent sequence type ST-17.
Results. During 13 years of observation, the predominance of Ia, III and V genotypes of GBS capsular polysaccharides was noted both in pregnant women and in newborns. The frequency of occurrence of genotype Ib increased from 0.7 to 6.7%, genotype V from 12.1 to 24.4%, and the prevalence of genotype III decreased significantly from 41.1 to 21.1%. Hypervirulent sequence type ST-17 was detected in 6 pregnant women and 2 newborns. However, there were no signs of neonatal infection in these children. More than half of all clinical isolates of S. agalactiae had pili genotypes PI-1 + PI-2a, as well as pili genotypes PI-2a and PI-1 + PI-2b. The distribution of pili types did not change over 13 years of the surveillance period.
Conclusion. Surveillance of the GBS capsular polysaccharides and pili genotypes is necessary for the development of effective preventive vaccines.
Spectroscopic In-Vitro Drug-Drug Interaction Studies of Amoxicillin and Paracetamol Solid Dosage Forms
Authors: Vaikosen Edebi N. , Bunu Samuel J. , Friday David , Ebeshi Benjamin U.
Published: May 2024

Potential drug-drug interactions (DDIs) are a public health concern in clinical therapy and drug development because of their contribution to actual adverse drug reactions (ADRs) or events. The study aimed to quantify the in-vitro drug-drug interaction of amoxicillin (AMX) and paracetamol (PCM) formulations which are commonly co-administered. Determinations were carried out by spectroscopic methods – zero-order and derivative spectroscopy. The data were analyzed using Microsoft Excel, 2016. The UV-Spectra of AMX and PCM showed two distinctive peaks at 240 nm and 260 nm were observed for AMX, while for PCM at 290nm and 340 nm, with maxima at 240 nm and 340 nm for AMX and PCM respectively. Absorption measurements were taken at the maximum wavelength of 290 nm and 240 nm for PCM and AMX respectively. The content of both drugs and potential DDIs of AMX and PCM were assayed by zero- and 3rd-derivative spectroscopy. The calibration curves for AMX and PCM standards showed good linearity at concentrations, with corresponding correlation coefficients (R) being 0.999 and 0.998. The intercept and slope for AMX were -0.0148 and 0.0732 respectively, while for PCM values were 0.0071 and 0.148. The content of PCM and AMX in the formulations was 98.40 ± 0.44% and 96.04 ± 0.29% respectively. The joint-drug-dissolution studies for AMX and PCM interaction (DDI) were obtained with the 3rd-order derivative spectroscopy at 210 nm (zero-crossing for PCM) and 290 nm (zero-line crossing for AMX) respectively - which showed overlapping spectra for their zero-order derivative spectra. No significant difference was observed in the in-vitro drug release profiles for AMX and PCM, while comparative profiles were observed to have a very strong correlation between individual-release and joint-release profiles.
A Study to Compare Spirometric Observations in Smokers and Non Smokers in Age Group between 25-55 Years
Authors: Randev Kranti , Kumar K Ramesh , Reddy Ramshanker , Prasad A Siva
Published: May 2024

In India, smoking is a common habit prevalent in both urban and rural areas irrespective of mode of smoking i.e beedis, cigarettes, cigars etc. Tobacco smoke contains 400 chemicals out of which 60 are known carcinogens, which can lead to lung cancer. Smoking leads to rapid decline in pulmonary function test. Cigarette smokers have a high annual rate of decline in FEV1 of about 50ml, which is nearly double the average value in non smokers.
Imaging Considerations in Polysplenia Syndrome in a Woman with Bilateral Breast Cancer
Authors: Mahir M. , Diani A. , Zouita B. , Basraoui D. , Jalal H.
Published: May 2024

Polysplenia syndrome is a rare congenital condition characterized by multiple spleens, as well as various other associated anatomical anomalies. When combined with a separate medical condition, such as bilateral breast cancer, the management and imaging considerations become particularly important. This article aims to explore the imaging modalities and considerations specific to a woman with polysplenia syndrome and bilateral breast cancer.
ANALISIS PERBANDINGAN APBD DALAM PERSPEKTIF OPTIMALISASI REALISASI ANGGARAN DAN PERHITUNGAN ANGGARAN SISA LEBIH (SiLPA) KEUANGAN PEMERINTAH KOTA PEKALONGAN TAHUN PEMBIAYAAN 2017-2020
Authors: Evana Maria , Munandar Agus
Published: May 2024

This research activity is for a comparative analysis of the budget in the perspective of optimizing budget realization and calculating the remaining budget (SiLPA) of the Pekalongan city government’s finances for the 2017-2020 fiscal year. Using five ratio analysis to calculate it, namely the degree of decentralization, independence ratio, effectiveness ratio, efficiency ratio and growth ratio. This study concludes that the average degree of decentralization in 2017-2020 is 15.45%, the results of regional financial independence have a consultative relationship, regional financial capacity is still low on development in paying regional taxes and levies, the results of the effectiveness and effective efficiency ratios, the ratio average PAD growth of 2.29%, total revenue of 3.37% and spending growth of 2.85%, there was a decrease in the number of SiLPA from 2017-2019 but there was an increase again in 2020 by 2%.
Keyword: Effectiveness, Efficiency, Rationality, SiLPA
Pengungkapan Green Intellectual Capital: Studi Deskriptif
Authors: Dyna Rachmawati  , Paskalis Yosephien
Published: May 2024

This study aims to describe the disclosure of green intellectual capital (GIC). GIC has not been widely explored in previous studies, especially in Indonesia. Therefore, this research will conduct a descriptive study of all public companies listed on the Indonesia Stock Exchange (IDX) with an observation period of 2020. The data collection method is documentation based on management letters in annual reports. The management letter used in this study consists of two reports, namely the report of the board of commissioners and the report of the board of directors. Management letters can  be regarded as a new source of data used by companies to disclose GIC information. GIC disclosure is measured using the content analysis method on keywords that represent each GIC component. The results of the descriptive study show that, first, the financial (agriculture) is the sector that most (little) expresses GIC. Second, structural capital (environmental capital) is the most (little) GIC component disclosed in management letter. The results of this study contribute, first, practically; management in companies with GIC disclosure levels has special attention to the importance of sustainability through green innovation. Second, structural capital is the easiest component to disclose in a management letter because management’s main concern is capital expenditure. Third, academically; the results of this study can enrich the GIC literature in Indonesia
Keywords: environmental capital, green intellectual capital, human capital, relational capital, structural capital
Pengaruh Leverage, Profitabilitas, Thin Capitalization dan Capital Intensity terhadap Agresivitas Pajak
Authors: Debora Laurensia
Published: May 2024

In taxation activities in Indonesia there are different significances, such as, the government and companies. The government maximizes tax levies for the properity of the people while companies jostling to tax planning to maximize profits and reduce tax payments, where taxes are one of the burdens of companies that can reduce profits. Based on these gaps, the study aims to test and analyze whether leverage, profitability, thin capitalization, and capital intensity affect aggressive taxes on the health sector listed on the Indonesia Stock Exchange for the period 2013-2020 The results of this study, the higher profitability will affect the occurrence of tax aggressiveness by focusing on company profits and the higher the debt on thin capilization is used to expand the company’s capital in running its business, in other words, the more the value of debt to the company affects the low level of aggressive tax avoidance in health sector companies.
Keywords: Capital Intensity, Leverage, Profitability, Tax aggressiveness, Thin capitalizatio
Multi - Industry Directorship dan Firm Value Pada Perusahaan Dalam Indeks Sri Kehati
Authors: Ani Salis Musta , Astuti Tri
Published: May 2024

The purpose of this study is to examine the existence of the SRI Kehati index in Indonesia Stock Exchange through testing governance variables (multi-industry commissioners and directorships, independence of commissioners) in companies of the SRI Kehati index as a driver of firm value. The reseach is a quantitative research by pannel data with random effect models. The results showed that the presence of directors handle multiple industries was able to encourage an increase in form value. Likewise, independent commisioners are able to increase firm value. The results of this study contribute to an overview of the level of readliness of companies in implementing the Sustainability Disclosure Standardand and indicate factors that can encourage an increase in firm value by paying more attention to social and environmental issues so that it can benefit public companies in general in the context of developing sustainability in Indonesia.
Keywords: Busy Director, Multy-Industry Directorship, Rating SRI Kehati, Sustainability
Detection of Pancreatic Tumor by The Radiological Measure of Curved Planar Reconstruction (CPR)
Authors: Ogura Katsunori , Bando Hiroshi , Kato Yoshinobu , Kawata Takafumi , Kato Yoshikane
Published: May 2024

The case involves a 74-year-old female with type 2 diabetes (T2D). HbA1c remained stable at 6% until summer 2019, but suddenly worsened to 8.4% in autumn 2019 without a certain reason. An abdominal CT scan detected a probable pancreatic tumor, which required further evaluation. Contrast-enhanced images of the arterial, portal vein, and equilibrium phase showed no staining, slight staining, and strong staining, respectively. The application of Curved Planar Reconstruction (CPR) has revealed an apparent pancreatic tumor image with three different stainings, associated with a dilated main pancreatic duct (MPD) in the pancreas body and tail and a normal MPD in the pancreas head. Consequently, CPR would be useful for diagnosis.
SCHOOL CULTURE AND WORK VALUES OF PUBLIC SECONDARY TEACHERS IN PANABO CITY DIVISION
Authors: Elben C. Enriquez  , Guillermo V. Dimaligalig
Published: May 2024

The study explored the relationship between school culture and work values of teachers in public secondary schools of Panabo City Division. Also, it investigated the association of the involved variables and the domains of school culture that significantly influence the work values of teachers. With the use of probability sampling, 150 secondary teachers in the public schools were selected as the respondents. Utilizing the descriptive-correlational survey method, the data collated were analyzed through the use of Mean, Product-Moment correlation and Regression Analysis. Results revealed that there was an extensive school culture and extensive work values of teachers. Furthermore, there was a significant relationship between the two variables. Moreover, all domains of school culture were found to have significantly influence on work values of teachers. Based on the findings, it was further suggested that higher officials in the Department of Education may identify means on how to help the school heads create a conducive school culture thereby helping teachers to develop positive work values. More so, future researchers may further explore the involved variables considering other factors and research methods.
KEYWORDS: School culture, work values, Panabo City Division
PROFESSIONAL LEARNING COMMUNITIES AND TEACHER’S MOTIVATIONAL STRATEGIES IN
PUBLIC SECONDARY SCHOOLS OF PANABO CITY DIVISION
Authors: Donde M. Necanor  , Lawrence Edward E. Zamora
Published: May 2024

The study explored the relationship between professional learning communities and teachers motivational strategies in public secondary schools of Panabo City Division. Also, it investigated the association of the involved variables and the domains of professional learning communities that significantly influenced teachers motivational strategies. With the use of probability sampling, 150 secondary teachers in the public schools were selected as the respondents. Utilizing the descriptive-correlational survey method, the data collated were analyzed through the use of Mean, Product-Moment correlation and Regression Analysis. Results revealed that there was an extensive professional learning communities and very extensive teachers motivational strategies. Furthermore, there was a significant relationship between the two variables. Moreover, all domains of professional learning communities were found to have significantly influence on teachers motivational strategies. Based on the findings, it was further suggested that higher officials in the Department of Education may identify means on how to help the school heads in empowering teachers of their motivational strategies by exposing them to varied professional learning communities.
KEYWORDS: Professional learning communities, teachers motivational strategies, descriptive correlation, Panabo City Division
Management and Consideration of Anesthesia Procedures in Eclampsia: A Case Report
Authors: Rauwelio Alvin , I Wayan Widana
Published: May 2024

Introduction: Eclampsia is a serious pregnancy complication with high maternal and fetal mortality rates. The choice of anesthetic technique in eclamptic patients must consider various factors, including the condition of the mother and fetus, the risk of complications, and the experience of the anesthesia team.
Case presentation: We report the case of a 21-year-old 39-week-old primigravida (G1P0A0) with severe eclampsia who experienced two tonic-clonic seizures. The patient was intubated in the emergency room and underwent an emergency caesarean section under general anesthesia. The patient was treated in the ICU for one day and extubated on the second day.
Conclusion: The choice of anesthetic technique in eclamptic patients must be done individually by considering various factors. The anesthesia team must be experienced in treating eclamptic patients and have the readiness to deal with complications that may occur.
When Will It Be Our Turn to Lead? An Evaluation of Women's Perceptions on Barriers to Access the Top Positions in Educational Institutions' Leadership in Kenya
Authors: Vundi Nason
Published: May 2024

This study evaluated women's perceptions of barriers to accessing the top positions in organisations' leadership in Kenya. The study had 3 specific objectives: to determine the women leaders' perceptions of the barriers to accessing top organisational leadership in Kenya; to establish how much support women leaders get in their attempt to access top organisational leadership in Kenya; to investigate the barriers women leaders face in their attempt to access top organisational leadership positions in Kenya. The research was a descriptive study preferred because it provides a comprehensive and accurate picture of the study subjects and to describe the inherent relationships, patterns, and trends demonstrated by the data analysed. The study findings were: women progression to top offices has not been easy, for example over 55% of the female Deputy Principals had stagnated for over 10 years in the same position without promotion. According to the study, about 22% of the respondents blamed patriarchy and gender stereotypes for their lack of promotion. Finally, the study found that family roles remains critical for the respondents. For example, 44% feared that promotion may result being sent far from home, while 39% did not apply for promotions due to family roles
Effect of Combining Non-Invasive Ventilation with Vitamin D on Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Authors: Wei Zhang , Yan Chen , Ming Zhai , Lianbo Zhao
Published: May 2024

This study aims to explore the effect of noninvasive ventilation combined with vitamin D in acute exacerbation of chronic obstructive pulmonary disease. Ninety-eight patients admitted to Mengcheng County NO.1 People’s Hospital were included. The control group received comprehensive treatment, including bronchodilators, glucocorticoids, antibiotics, and expectorants, correction of water and electrolyte imbalance, and nutritional support. Based on the control group, patients in the treatment group received non-invasive ventilation combined with vitamin D. After therapy, the treatment group showed a higher total effective rate compared to the control group. The treatment group exhibited a more pronounced decrease in the partial pressure of carbon dioxide and an increase in the partial pressure of oxygen in arterial blood and arterial oxygen saturation compared with the control group. The levels of forced vital capacity and forced expiratory volume in the first second were higher in the treatment group. Moreover, interleukin-6, C-reactive protein, and procalcitonin levels were lower, while CD3+, CD4+, CD8+, and CD4+/CD8+ levels were higher; quality-of-life scores were lower. Combining non-invasive ventilation with vitamin D can improve blood gas indexes, promote lung function, reduce inflammatory response, and promote immune function in patients with acute exacerbation of chronic obstructive pulmonary disease.
Synergistic Effects of Chlorogenic Acid and Ganoderma Lucidum Polysaccharide on Hepatic Fat Accumulation
Authors: Tianyu Wang , He Xu , Yue Sun , Jumin Hou , Liying Yin
Published: May 2024

This study aimed to investigate the impact of different doses of chlorogenic acid and Ganoderma lucidum polysaccharide on lipid accumulation using an obese rat model. We utilized blood glucose assays, oil red O staining, and triglyceride content analysis to examine the effects of chlorogenic acid combined with G. lucidum polysaccharide on fat metabolism in rats. We found substantial potential in using chlorogenic acid combined with G. lucidum polysaccharide for weight control and metabolic regulation in obese rats. After a long-term dietary intervention, chlorogenic acid and G. lucidum polysaccharide markedly inhibited the expression of proteins related to fatty acid synthesis, including AMP-activated protein kinase, fatty acid synthase, and SREBP-1c, leading to reduced body weight and decreased hepatic fat deposition. Additionally, the combined treatment substantially affected enzymes and proteins involved in glucose metabolism, reducing glycogen synthase expression and indicating a potential mechanism for weight reduction through glycogen synthesis inhibition. Furthermore, elevated glucose kinase levels indicated that chlorogenic acid and G. lucidum polysaccharide may enhance hepatic glycogen degradation, thereby reducing hepatic fat accumulation. These findings reveal that chlorogenic acid combined with G. lucidum polysaccharide has a synergistic impact, providing a theoretical basis for their potential as a combined therapeutic approach for obesity.
Sales Enablement in Business-to-Business (B2B) Context: An Exploratory Case Study on Implementation and Key Areas
Authors:   Department of Economics and Law University of Macerata, Macerata, Italy, Severini Simone , Romoli Alessandro ,   International Studies of Rome University, Department of International Humanities and Social Sciences, Rome, Italy, Cardinali Silvio ,   Department of Management, University Polytechnic of Marche, Ancona, Italy
Published: May 2024

In recent years, sales organizations have faced a complex array of operational challenges, ranging from a shift towards remote work to fluctuating customer expectations and increasing market competition. To overcome these issues, many business-to-business (B2B) firms have adopted sales enablement strategies, a field gaining both practitioner and academic attention, but lacking a standardized definition. Employing a two-step analytical approach, this study aimed to elucidate the concept of sales enablement. It accomplishes this by conducting a comprehensive analysis of existing definitions within the practitioner landscape and exploring its practical application through a single case study. Our findings significantly advance the existing body of knowledge by identifying three key elements that are essential for effective sales enablement implementation: alignment, integration, and processes. In contrast to the prevalent focus on technology as the cornerstone of sales enablement, our study reveals a more nuanced perspective. It posits that, while technology is an important facilitator, the key themes of effective sales enablement are alignment among people, integration of organizational resources, and streamlined processes. These insights provide valuable contributions to both the academic literature and the practical application of sales enablement, offering a multifaceted understanding that extends beyond mere technological focus to encompass human and process-oriented dynamics.
Common Fixed Point Results Related to Generalized F-Contractions in Extended Cone b-Metric Spaces
Authors: Selko Zamir , Sila Eriola
Published: May 2024

This paper presents a new class of F-functions defined on a cone and proves some theorems showing the uniqueness and existence of common fixed points for two functions satisfying a generalized F nonlinear contractions condition in extended cone b-metric spaces. Several examples illustrate the main theorems and demonstrate the applicable side of theoretical results.
Direito Civil e os pobres: a obra de Anton Menger desde a ótica do Direito do Trabalho contemporâneo
Authors: Sestari Bruna Rosa , Toledo Filho Manoel Carlos
Published: May 2024

O objetivo deste trabalho é realizar uma breve análise da obra “O Direito Civil e os Pobres” escrita por Anton Menger desde a ótica do Direito do Trabalho Contemporâneo. No mencionado livro, Menger articula uma crítica contundente à maneira pela qual o direito civil reproduz e perpetua desigualdades, propondo, em contrapartida, reformas que visem à proteção dos direitos trabalhistas e ao bem-estar dos trabalhadores.
impacto do capitalismo de vigilância e da datificação social nas dinâmicas globais de trabalho
Authors: Cardoso Barzotto Luciane , Soletti Alles Matheus
Published: May 2024

Contextualização: No contexto do capitalismo de vigilância e datificação social, este artigo explora a transformação nas relações laborais, marcada pela informatização dos processos sociais e laborais e pela intensa coleta e análise de dados pessoais.
Objetivo: Investiga-se as implicações dessas práticas no ambiente de trabalho, onde a privacidade e a autonomia dos trabalhadores são frequentemente comprometidas.
Método: Por meio de revisão da literatura e da legislação, analisa-se as respostas jurídicas globais a essas mudanças, destacando a necessidade de equilibrar a inovação tecnológica com a proteção dos direitos fundamentais dos trabalhadores em um mundo crescentemente monitorado e digitalizado.
Resultados: O estudo visa oferecer uma visão crítica sobre as dinâmicas emergentes nas relações de trabalho e o papel do direito em moderar as tensões entre a vigilância corporativa e a liberdade individual.
Topic Modeling for Evolving Textual Data Using LDA, HDP, NMF, BERTOPIC, and DTM With a Focus on Research Papers
Authors: Pavithra  , Savitha
Published: May 2024

As the volume of academic literature continues to burgeon, the necessity for advanced tools to decipher evolving research trends becomes increasingly apparent. This study delves into the utilization of topic modeling techniques—specifically Latent Dirichlet Allocation (LDA), Hierarchical Dirichlet Process (HDP), Non-negative Matrix Factorization (NMF), BERTopic, and Dynamic Topic Modeling (DTM)—applied to a dynamic corpus of research papers. Our research endeavors to confront the challenges posed by capturing temporal dynamics, evolving terminology, and interdisciplinary themes within academic literature. Through a comprehensive comparative investigation of these models, we assess their efficacy in extracting and tracking research topics over time. While DTM exhibited the highest term topic probability, its inclusion of non-meaningful words proved to be a hindrance to its suitability. Conversely, NMF, HDP, LDA, and BERTopic demonstrated comparable performance in topic extraction. Surprisingly, DTM emerged as the most effective model in our research, showcasing its prowess in navigating the intricacies of evolving research trends.
El Dibujo como Herramienta para Fortalecer la Atención en Clase: Propuesta Didáctica para Estudiantes de Tercer Grado de Primaria
Authors: Tejeda Martínez Alejandra , Riaño Arias Esteban , Mondragón Mesa Diego Javier
Published: May 2024

El presente estudio tuvo como objetivo describir, indagar e identificar las posibilidades del dibujo como herramienta para fortalecer la atención en niños de 8 y 9 años de edad que cursan el tercer grado de Educación Básica; así como proponer actividades didácticas que puedan realizarse en las sesiones de clase. El diseño del estudio es de tipo cualitativo con un alcance descriptivo. Se reconoce que el desempeño de los estudiantes en el aula está asociado a múltiples factores que influyen de manera directa en los procesos de aprendizaje, siendo uno de ellos, la atención. Por otra parte, se aborda la relación que existe entre el dibujo como forma de representación y los beneficios que supone la enseñanza y aprendizaje de ésta y de otras formas de representación propias de las artes dentro de las propuestas curriculares.
Description of a new Pheosia from Sichuan and Gansu, China (Lepidoptera, Notodontidae)
Authors: Saldaitis Aidas , Prozorov Alexey M. , Morozorov Pavel S. , Yakovlev Roman V. , Müller Günter C. , Dûda Juozas
Published: May 2024

A new species of the genus Pheosia Hübner, 1819, Pheosia mayri sp. n., from Sichuan and Gansu Provinces in China is described. The new species is compared with Chinese Pheosia gelupka Gaede, 1934 and Pheosia buddhista (Püngeler, 1899). The two differ in wing coloration, male and, especially, female genitalia. Adults of both sexes, their genitalia and map of collecting sites are illustrated.
ENTRE O DESESPERO E A RESISTÊNCIA: UM RELATO DO DESASTRE DO PETRÓLEO NA RESEX CANAVIEIRAS
Authors: Machado Louise Oliveira Ramos , Santos Tiala Santana , Santos Lilian Santana , Lima Mara , Santos Luciene de Almeida , Mota Luize da Silva Rezende da , Rêgo Rita de Cássia Franco
Published: May 2024

A Reserva Extrativista de Canavieiras (RESEX), é uma Unidade de Conservação Federal, gerida pelo Instituto Chico Mendes de Conservação da Biodiversidade - ICMBio, foi instituída em 2006 e abrange uma área de 100.726,36 hectares, sendo que, dos 100 mil hectares da área, 83% correspondem à parte oceânica, 12% são restingas e manguezais e o restante (menos de 5%) constitui áreas de terra firme (BRASIL, 2006; PEDREIRA; ROCHA, 2022). Localizada no sul da Bahia (Figura 1), abrange os municípios de Canavieiras, Belmonte e Una. Essa Resex tem como objetivos proteger os meios de vida e a cultura da população extrativista residente na área de sua abrangência e assegurar o uso sustentável dos recursos naturais da unidade (BRASIL, 2006).
O GRITO DE LUTA E A RESISTÊNCIA DE MARISQUEIRAS AFETADAS PELO DERRAMAMENTO DE ÓLEO NO LITORAL DE SERGIPE
Authors: Carvalho Mariana Nascimento , Moraes Leidineia da Silva , Santos Tiala Santana , Costa Ana Elisia Pereira , Flores Elienaide Cardoso das , Santana Crislaine dos Santos
Published: May 2024

O município de Indiaroba, onde estão localizadas as comunidades de Terra Caída, Pontal e Preguiça, está situado na região que compõe a APA Litoral Sul de Sergipe. Ao longo das últimas décadas, esses territórios vêm enfrentando as consequências de transformações antrópicas e conflitos socioambientais, a exemplo do derramamento de petróleo. Tais conflitos se acentuam com a fragilidade de ações fiscalizatórias e de políticas públicas protetivas. A presença do óleo no mar e no mangue, afetou o ambiente e a vida de pescadores(as) artesanais, com repercussões para a saúde, a condição socioeconômica e a segurança alimentar. Além disso, destaca-se as insuficientes ações governamentais frente ao derramamento que versam sobre a falta de ações mitigatórias e compensatórias. Nesse contexto apresentado, as trabalhadoras da pesca continuam a lutar pela garantia de direitos e mudança do atual cenário. Diante da falta de perspectiva de melhora e do convívio com dúvidas e incertezas, mobilizam os sentidos de coletividade pela busca de respostas.
O ALERTA GENERALIZADO DAS NOTÍCIAS DE CONTAMINAÇÃO DO PESCADO E OS EFEITOS DESASTROSOS NA CADEIA PRODUTIVA DE FRUTOS DO MAR
Authors: Silveira Mariana F. da , Olavo George
Published: May 2024

Em 2019, o maior desastre ambiental do litoral brasileiro não apenas causou enormes impactos ecológicos para o meio-ambiente, mas também graves consequências econômicas e sociais para a população que depende dele. As notícias de contaminação do pescado e dos riscos para a saúde humana tiveram repercussões socioeconômicas bastante negativas para todas as comunidades de pescadores, independente da chegada do óleo na localidade. Enquanto a cobertura da mídia foi ampla, por meio de diferentes plataformas, as recomendações sobre o consumo do pescado não foram prontamente publicadas para a população e, por vezes, foi contraditória entre pesquisadores e agências do governo.
Radioterapia preoperatoria en cáncer de mama como estrategia terapéutica, a propósito de un caso
Authors: Bahsas Osama , Solorzano Luis , Villegas Wladimir , Gómez Álvaro
Published: May 2024

Múltiples estrategias terapéuticas se han desarrollado con el objetivo de optimizar el tratamiento del cáncer de mama, especialmente antes de ir a quirófano, desde la introducción de la quimioterapia preoperatoria por Fisher. Una de estas ha sido la radioterapia, la cual tiene beneficios claros en esa patología, pues reduce a la mitad el riesgo de recurrencia, y disminuye la muerte por cáncer de mama en aproximadamente una sexta parte después de cirugía conservadora. Aunque no se suele considerar antes de la cirugía, el uso de radioterapia preoperatoria en cáncer de mama, no es nuevo, y se ha demostrado que esta alternativa terapéutica es factible, bien tolerada y asociada a una tasa de respuesta patológica completa del 10 % - 40%. Se presenta el caso de una paciente con cáncer de mama metastásico, quien recibió múltiples esquemas de quimioterapia y a quien se le planteó radioterapia preoperatoria, recibiendo la misma con muy buena respuesta, sin aumentar la dificultad técnica para la realización de la intervención quirúrgica, y sin complicaciones asociadas a la herida operatoria. En la actualidad, existen pocos estudios clínicos sobre radioterapia preoperatoria, y su efecto en las pacientes con cáncer de mama localmente avanzado, es controvertido. Al observar en la biopsia definitiva respuesta patológica completa, es un indicio de cómo la radioterapia preoperatoria en cáncer de mama podría ser una opción en casos complejos con poca respuesta a la terapia convencional.
Los conflictos y su manejo en el ambiente universitario
Authors: Rodríguez Jesús
Published: May 2024

Los conflictos son parte de la existencia humana, que, por su gregarismo, habitualmente convive en comunidad; generan o inducen a transformaciones y mejoras, aparecen en cualquier momento y pueden ser repetitivos; constituyen una oportunidad de progresar si son bien manejados, es decir, con razones y sin violencia. Las universidades no están exentas a su presencia, y deben estar preparadas para enfrentarlos. Para solucionarlos, lo primero es que haya interés genuino en ello por las partes, sin agendas ocultas, sin propuestas fantásticas sino viables; y tener el convencimiento de que no se necesitan ganadores o perdedores sino beneficiados. La secuencia lógica para superarlos, son: conocer y reconocer su existencia, definir cuáles aspectos deben solucionarse primero, mejorar la comunicación entre las partes, plantear alternativas, elegirlas, ejecutarlas y medir los cambios. Los enfoques para solucionarlos, son: normativos (aplicar la ley, reglamentos o costumbres razonablemente establecidas), negociados o resolución (se supera el conflicto, mas no se resuelve) o transformaciones de conflictos: cuando se resuelve, además, la causa. Aunque por definición, no son lo mismo, el uso ha hecho equivalentes la resolución a la transformación. En general, se escoge entre facilitación (con un imparcial ayudando a conflictuados que han logrado mantener relaciones aceptables), mediación (las partes escogen a un mediador pues no tienen comunicaciones efectivas, para buscar puntos de encuentro efectivos), indagación de hechos (con un indagador ajeno que se centra en los desacuerdos técnicos) y arbitraje (un juez que decide todo lo que hay que hacer): son menos traumáticos la facilitación y la mediación(1-2).
Characteristics of her2-positive breast cancer, and the current use of anti-her2 therapy and its related factors
Authors: Ho Xuan Dung
Published: May 2024

ABSTRACT

Objective: To describe the characteristics of patients with HER2-positive breast cancer and to identify the proportion of patients using anti-HER2 therapy, and treatment-making related factors.

Methods: An analytical cross-sectional study was conducted on 79 patients with BC and HER2-positive diagnosed by immunohistochemistry (IHC) or with FISH at the Oncology Department of Hue University of Medicine and Pharmacy Hospital and Oncology Center of Hue Central Hospital from 1/2021 to 12/2022. Clinical and pathological features, type of drug, number of cycles using anti-Her2 therapy were recorded using medical documents. The decision-making related factors were recorded by questionnaire interviewing patients and relatives. Exclusion criteria included recurrent or previously treated tumors; having contraindications with anti-HER2 therapy; not being willing to participate in the study. SPSS 22.0 was used for the analysis.

Results: Mean age was 54.14 ± 11.03. Patients with right-sided BC accounted for 53.1%. 60.8% of tumors were located in the upper right quadrant of the breast. Patient’s self-report of lumps was the most common cause of hospitalization (77.2%). By ultrasound, 60.2% of participants had a tumor size of 2 - 5cm. Abnormal lymph nodes were identified in 40.8% of patients. Histopathologically, invasive ductal carcinoma was found in the majority of tumors (75.9%). Stage II was predominant with 59.5% and 7.6% of patients with stage IV. The rate of treatment with Trastuzumab in our study was 27.8%. The main reason that patients refused anti-HER-2 therapy was financial problems (96.5%). The awareness of anti-HER2 therapy among patients and their relatives was significantly associated with the treatment decision (p = 0.007).

Conclusion: Regarding the positive-HER2 BC patients, invasive ductal carcinoma was the major histopathological finding. More than half of the patients were classified as stage II of the disease. The rate of patients undergoing antiHER2 therapy was 27.8%. Financial problems were found to be the main reason for refusal of treatment. Awareness of anti-HER2 therapy is significantly associated with the patient’s decision on treatment.
Atmanirbhar Bharat Abhiyan: Boost to Agriculture Sector
Authors: R. Shettar Madhumati. , G. Kadapatti Ratnamala
Published: May 2024

Restricted mobility of people and goods poses severe supply side disruptions. Produced farm output was decayed due to restricted movement creates fall of total demand. Agriculture and allied sectors needs an attention as they are producer of food to millions of people and animals. On May 2020 Atmanirbhar Bharat Abhiyan was announced and released 20 crore as relief fund. This paper is studying about the benefits derived from ABA relief fund. It collected secondary data from various government reports analyzed the data by using simple mathematical tools and graphs. The present study observed that there is buoyant growth of agriculture and allied sector in past two years.
Synthesis of Perylene Diimide Modified by POSS and its Assembly Behavior in Solution and SBS Matrix
Authors: Arslan Muhammad , Jia Chen , Haoru Zhao , Dandan Gu , Yangshuang Xiang , Xiaoze Jiang , Bin Sun
Published: May 2024

In this work, Perylene diimide derivatives 1,7- POSS-PDI-C12 (PPC) were synthesized using 1,7-Br-PDI- C12, 18-crown-6 ether as phase transfer agent, K2CO3 as catalyst and THF as solvent in a reaction system. Subsequently, the POSS-SH group was successfully introduced into the perylene imide bay site in high yield. The chemical structure and molecular weight of the products were characterized by 1H-NMR, 13C-NMR, MALDI-TOF MS and FT-IR. The self-assembly behavior in different solvents was studied using the research solution self-assembly method. PPC remained in a single monomolecular state due to the bulky POSS group, which introduced large steric hindrance in the molecular packing, leading to the weakening of the π–π interactions. Then, the Composite thin films containing PPC in SBS was prepared. PPC do not exhibit significant force-chromic behavior owing to the dispersion of single- molecule states. This shows that in the construction of mechanochromic materials, chromophore molecules need to have a certain degree of aggregation in the matrix, but the aggregation degree should not be too high.
The Experimental Investigation of the Machinability of Armor Steels
Authors: Asmafiliz Caner , Isık Yahya
Published: May 2024

In recent years, the use of materials with ultra-high hardness such as Millux Protection 600T has become widespread in industry. However, the effect of different parameters used in the machining process of such steels, especially factors such as feed rate, cutting speed, depth of cut, and radial depth of cut, on the surface roughness of the final product is still not fully understood. In this context, a study was conducted to evaluate the effects of the mentioned armor steel on surface roughness. Using the Taguchi optimization method, the interaction between processing parameters at specified levels was examined, and attempts were made to determine the optimum values. Within the scope of the study, nine different experiments were conducted using Taguchi's L9 orthogonal array, and the surface roughness data obtained from each experiment were recorded. According to the analysis results, it was determined that the feed rate is the most significant parameter in the milling process, followed by radial depth of cut, depth of cut, and cutting speed, respectively. To achieve optimal results, it is recommended that the feed rate be set to level 1, cutting speed to level 2, depth of cut to level 1, and radial depth of cut to level 3. These findings could provide important guidance in the machining of such steels.
Jonathan Odell and Laurence Sterne: A Transatlantic Connection
Authors: WALKER ROBERT G.
Published: May 2024

Students of early American literature, especially those who like satire, may be familiar with Jonathan Odell (1737-1818), Anglican priest, physician, and Loyalist poet. Students of Laurence Sterne probably will not be. Yet there are a series of remarkable conjunctions between the two writers, showing Sterne’s reach to the colonies, as well as Odell’s ability to maintain contact with the London literary world despite living most of his life on another continent. This essay examines the influence Sterne had on Odell, especially on his satiric poetry. There is no claim within that the two men’s politics were similar. In fact, that is unlikely. But their taste in literature was indeed coincident — an appreciation of Swift and Pope, for example — and that was reflected in Odell’s alluding to various well-known components of Sterne’s canon in his poetry, and especially in his repeated selection of Yoric[k] as a pseudonym and persona.
Two Satyrs Against Travelling: The Arts and the Grand Tour in
Peregrine Pickle
, Vol. 2, and
Tristram Shandy
, Vol. 7
Authors: LIPSKI JAKUB
Published: May 2024

Comparisons between Tobias Smollett and Laurence Sterne have typically been based on
Travels through France and Italy
and
A Sentimental Journey.
Here, the travel sections of
Peregrine Pickle
and
Tristram Shandy
inform a comparative discussion of both authors’ differing pursuit of continental travel as aesthetic experience and their satirical reworking of contemporary Grand Tour narratives.
‘The life of a Wit is a warfare upon earth’: Sterne, Joyce, and their Portraits of the Artist
Authors: NEW MELVYN
Published: May 2024

Acknowledging Peter de Voogd’s dual dedication to Sterne and Joyce and my own interest in Sterne and Modernism, this essay explores the portraits of Stephen Dedalus and Tristram Shandy as each develops the aesthetic values that will shape their artistic careers. While Stephen emerges from a Dublin in conflict over politics and religion, Tristram’s childhood is shaped by Walter’s opinions and arguments supporting them — and the result of human quarrelsomeness, enacted on Toby’s bowling green. Relevant to their artistic development are the sermons each author provides. Yorick’s ‘Abuses of Conscience’ sermon introduces to the reader the Christian worldview wherein Judgment and Truth matter, but the death of Yorick in the early pages frees Tristram into a world of directionless indeterminacy and the relativity of all values, the Shandy world. Father Arnall’s sermon, on the other hand, is so intent on colouring all human desire with the taint of hellfire (compare Ernulphus’s curse in
Tristram)
that it frees Stephen from the vocation, although, as will become apparent in
Ulysses,
his life as an artist is permanently marked, as is Modernism more generally, by his inability to free himself from the aesthetic values of Judgment and Truth, which continue to exert their domination as the qualities that distinguish meaningful artistic endeavour.
The Soviet Beauties of Sterne?: Censoring Sterne in Soviet Russia
Authors: BUDRIN PETER
Published: May 2024

This article discusses an odd Soviet edition of
A Sentimental Journey.
In 1935
Ogonek’s Library (Biblioteka Ogon’ka),
a weekly literary supplement to the massively popular magazine
Ogonek,
issued a small-format pamphlet containing an abridged edition of Sterne’s
Sentimental Journey.
This publication, with a print run of 50,000 copies, recycled a pre-revolutionary translation by the playwright Dmitry Averkiev (1836–1905) and was supposed to provide the Soviet Russophone readers with an accessible introduction to the British author’s writings and personality. This abridged edition is a peculiar product of Soviet censorship which changes the meaning of the important episodes of
A Sentimental Journey
in unexpected ways.
Classification of Astronomical Spectra Based on Multiscale Partial Convolution
Authors: Wu Jingjing , He Yuchen , Wang Wenyu , Qu Meixia , Jiang Bin , Zhang Yanxia
Published: May 2024

The automated and efficient classification of astronomical spectra is an important research issue in the era of large sky surveys. Most current studies on automatic spectral classification primarily focus on specific data sets and demonstrate outstanding performance. However, the diversity in spectra poses formidable challenges for these classification models, as they exhibit limited capability to generalize across more comprehensive data sets. In response to these challenges, we pioneer a method called the multiscale partial convolution net (MSPC-Net), which amalgamates partial, large kernel, and grouped convolution to facilitate multilabel spectral classification. By harnessing the capabilities of partial convolution, MSPC-Net can effectively reduce the number of model parameters, accelerate the training process, and mitigate the overfitting issue. Integrating large kernel and grouped convolution empowers the model to capture local and global features simultaneously, enhancing its overall classification efficacy. To rigorously evaluate the model’s performance, we generate ten different data sets sourced from the Sloan Digital Sky Survey and Large Sky Area Multi-Object Spectroscopic Telescope. These data sets encompass stellar class, stellar subclass, and full classification, providing a comprehensive assessment across various application scenarios. The experimental results reveal that MSPC-Net consistently outperforms the other models across different data sets, especially demonstrating superior performance in the last two data sets with full classification. Consequently, MSPC-Net is poised to find extensive applications in the detailed classification for large-scale sky survey projects. This work not only addresses the challenges of generalization in spectral classification but also contributes significantly to the advancement of robust models for astronomical research.
The Mass Density of Mg ii Absorbers from the Australian Dark Energy Survey
Authors: Abbas Asif , Churchill Christopher W. , Kacprzak Glenn G. , Lidman Christopher , Guatelli Susanna , Bellstedt Sabine
Published: May 2024

We present an all-southern sky survey for Mg ii
λλ2796, 2803 doublet absorbers in 951 z < 4 active galactic nucleus/quasar spectra from the Australian Dark Energy Survey. The spectral resolution ranges from R = 1400 to 1700 over the wavelengths 3700–8800 Å. The survey has a 5σ detection completeness of 50% and above for rest-frame equivalent widths W

r
(2796) ≥ 0.3 Å. We studied 656 Mg ii absorption systems over the redshift range 0.33 ≤ z ≤ 2.19 with equivalent widths 0.3 ≤ W

r
(2796) ≤ 3.45 Å. The equivalent width distribution is well fit by an exponential function with W
* = 0.76 ± 0.04 Å, and the redshift path density exhibits very little evolution. Overall, our findings are consistent with the large, predominantly northern sky, surveys of Mg ii absorbers. We developed and implemented a Monte Carlo model informed by a high-resolution Mg ii survey for determining the Mg ii mass density, ΩMg II
. We found ΩMg II
∼ 5 × 10−7 with no evidence of evolution over a ∼7 Gyr time span following Cosmic Noon. Incorporating measurements covering 2.0 ≤ z ≤ 6.4 from the literature, we extended our insights into Mg ii mass density evolution from the end of reionization well past the Cosmic Noon epoch. The presented Monte Carlo model has potential for advancing our knowledge of the evolution of mass densities of metal ions common to quasar absorption line studies, as it exploits the efficiency of large low-resolution surveys while requiring only small samples from expensive high-resolution surveys.