bluuebunny/crossref_metadata_2025 huggingface dataset:
The relationship of polymorphisms of the SOD2, NOS3 and SIRT1 genes with hypertension in employees of the converter workshop of the ferrous metallurgy enterprise
Authors: Bereza Ivan A. , Shaikhova Daria R. , Amromina Anna M. , Polyanina Daria D. , Gazimova Venera G. , Shastin Aleksandr S. , Astakhova Svetlana G. , Sutunkova Marina P. , Gurvich Vladimir B.
Published: February 2024

Workers employed in ferrous metallurgy enterprises are affected by various oxidants, which lead to increased formation of free radicals, suppression of the antioxidant system, initiation of oxidative stress and the development of diseases characterized by high blood pressure. In this regard, the identification of polymorphisms of genes encoding enzymes that are associated with the formation and neutralization of free radicals is an important task of personalized medicine.
The study aims to explore the relationship of polymorphisms rs4880 (SOD2), rs1799983 (NOS3) and rs7069102 (SIRT1) with hypertension in workers of the converter workshop.
To conduct the research the authors used data from periodic medical examinations of men aged 30 to 59 years, including 116 employees of the converter shop and 169 representatives of administrative and managerial personnel (comparison group). Subsequently, we divided each group according to the principle of the presence or absence of a diagnosis of "hypertensive heart disease" (I11 according to ICD-10), established or confirmed during a periodic medical examination. DNA was isolated from peripheral blood using the Lumiere kit for the isolation of genomic DNA from whole blood and literal epithelium (Lumiprobe, Russia) in accordance with the manufacturer's instructions. The scientists performed genotyping using the optical PCR system with real-time optical detection QuantStudio 3 (Thermo Fisher, USA) and ready-made commercial sets "SNP-Screen" (Syntol, Russia).
The ratio of the chances of developing hypertension in the personnel of the converter shop was increased in carriers of mutant genotypes of the SOD2 (TT) gene. Also, the values of blood pressure, total cholesterol and glucose levels were higher in carriers of the mutant TT genotype of the SOD2 gene compared with CC/CT, but only in the group of converter shop workers with hypertension. In addition, in the comparison group with hypertension, systolic and diastolic blood pressure significantly differed, the values of which were higher in carriers of the mutant GG genotype of the SIRT1 gene.
Presumably, an excess of superoxide anion in the TT genotype of the SOD2 gene, together with exposure to harmful environmental factors, may contribute to the development of cardiovascular diseases in workers of the converter workshop.
Ethics. The study was approved in accordance with Protocol No. 1 dated 02/26/2021 and the conclusion of the Local Ethics Committee of the Federal Budgetary Institution of Science "Yekaterinburg Medical Scientific Center for the Prevention and Health Protection of Industrial Workers" of Rospotrebnadzor.
Evaluation of some oncomarkers and cytokines in vinyl chloride workers
Authors: Bodienkova Galina M. , Boklazhenko Elena V.
Published: February 2024

Currently, there is a serious problem of the risk of developing oncopathology in chemical enterprises. Numerous workers in the chemical industry, including vinyl chloride and polyvinyl chloride (VC and PVC), are exposed to a complex of chemical compounds that, among other things, have carcinogenic effects and affect many body systems. The immune system has the ability to recognize malignant cells with subsequent activation and hyperactivation of immune responses, including cytokine production. To date, the details of cytokine control and, moreover, the ways of manipulating the antitumor immune response remain insufficiently studied.
The study aims to evaluate changes in serum concentrations of certain cancer markers, cytokines and their relationships in highly trained vinyl chloride production workers.
The authors have determined serum concentrations of cancer markers (CA 19-9; CEA) and interleukins (IL-1β, IL-2, IL-4, IL-8, TNF-α, INF-γ) using the method of solid-phase enzyme immunoassay.
As a result of the study, the researchers found that the highest concentrations of carbohydrate antigen (CA 19-9) are characteristic of trained workers, and when analyzing their level of embryonic cancer antigen (CEA), its tendency to increase attracts attention, which significantly increases the likelihood of cancer pathology in workers. Also, in most workers of this production, we observed hyperproduction of IL-4, IL-8, TNF-α, INF-γ against the background of a decrease in IL-1β and IL-2. At the same time, an increase in the concentration of CA 19-9 was accompanied by a decrease in the levels of IL-8 and INF-γ, which may lead to the preservation of cancer risks.
Thus, the assessment of changes in the content of markers of oncopathology, inflammatory mediators and their relationships among workers in the production of VC and PVC indicates and confirms the role of violations of the mechanisms of immunoregulation underlying the formation of various pathologies, including oncological ones. Further study of the mechanisms of cytokine regulation of the antitumor immune response will contribute to improving the methods of early diagnosis and prevention of disorders in the body of workers at carcinogenic enterprises.
Ethics. The study was conducted in compliance with Ethical standards in accordance with the Helsinki Declaration of the World Medical Association.
Distance modulates urgency to act and action awareness
Authors: Kong Gaiqing , Desoche Clément , Miller Luke E. , Pavani Francesco , Haggard Patrick , Vernet Marine , FARNE ALESSANDRO
Published: February 2024

Peripersonal space (PPS) - the immediate space surrounding our body - is known to enhance perceptual and neural processes. However, whether PPS influences voluntary action initiation and its temporal awareness remains underexplored. In this study, we tested whether spatial proximity per se affects the initiation of voluntary actions and the temporal awareness of associated events - from decision to action execution. Using an adapted Libet clock paradigm within a virtual reality environment, participants were presented with a clock either within their PPS (Near) or outside it (Far). They were required to initiate spontaneous actions and either report the perceived timing of their decision to act, report the timing of their action execution, or make no report. Results showed that when participants were not required to estimate timings, they initiated their actions earlier when the Libet clock was within PPS compared to when it was outside PPS. This suggests that there is an urgency induced by spatial proximity, which may be reduced by cognitive demands. Additionally, when the clock was within PPS, participants perceived their action decision and execution as occurring earlier than when it was outside PPS. By revealing that spatial proximity objectively modulates action urgency and subjectively influences temporal awareness of actions, these findings disclose a critical role of PPS in voluntary decision-making and temporal awareness. These results highlight a previously overlooked role of distance in decision-making processes and call for further experiments to understand how proximity can shape our experience of agency and control over actions.
Estado de la información en 2023: noticias sobre documentación, bibliotecas, internet, contenidos digitales y comunicación
Authors: Baiget Tomàs
Published: February 2024

Recopilación de las principales efemérides y noticias españolas e internacionales producidas durante 2023 sobre documentación, bibliotecas, internet, contenidos digitales, comunicación social y publicación científica.
Legal regulation of the protection of women from domestic violence in Western Europe
Authors: Yara Olena , Golovko Liudmyla , Kapplová Olga , Medvedska Viktoriia , Funta Rastislav
Published: February 2024

The relevance of the stated issue is explained by the constant increase in the number of reports of domestic violence in the vast majority of European countries. The purpose of the study is to conduct a comparative analysis of the legal framework for protecting women from domestic violence in Western European countries using the examples of Italy, Germany, and France. General theoretical methods of research, namely abstract-logical, systemic-functional, analysis and synthesis, and the comparative method, were used in the paper. It was clarified that the criminalisation of domestic violence victims has become a gradual trend in Western European countries. Protective measures such as issuing protection orders, using Global Positioning System bracelets to track perpetrators, and increasing responsibility for committing domestic violence have been implemented. The necessity of criminalising the crime of stalking was justified in Ukraine. Western European countries actively combat domestic violence in general and towards women in particular. It is established that the feature of the German legal system is the presence of specialised police units whose activities are aimed at protecting victims of domestic violence. France focuses on developing state programmes aimed at protecting individuals who have experienced family violence. In all analysed countries, the legislation ensures the protection of domestic violence victims through the issuance of protective orders. The analysis of the legislation of Italy, Germany, and France disclosed features of legal regulation regarding the protection of women from domestic violence and identified advantages and disadvantages that may exist in this area. The results of the study can be used in the research field as a basis for further studies on the protection of women from domestic violence and in legislative activities, providing recommendations for changes to Ukrainian legislation.
Плата за землю: колізії податкового законодавства
Authors:   Уповноважений Верховної Ради України з прав людини у Дніпропетровській області, НЕДОСТУП Катерина , ГРЕСЬ Наталія ,   Національний технічний університет "Дніпровська політехніка"
Published: February 2024

Законодавча довершеність порядку введення в податкову систему місцевих податків і про­цедур їх справляння сприяє наповненню місцевих скарбниць. Метою статті є перевірка узгодже­ності положень розділу ХІІ Подат­ко­вого кодексу України (в частині плати за землю) з нормами ст. 7, 10, 15, 22 цього правового акта. У ході дослідження використано такі методи наукового пізнання: контент-аналіз, системно-структурний, логічні (аналіз, синтез, узагальнення, дедукція, індукція); застосовано аргументацію. Зʼясовано, обʼєктом оподаткування якими податками є земельні ділянки, що перебу­вають у власності, строковому платному володінні чи користуванні. Відзначено розбіжність назв обовʼязкових, безумовних платежів до місцевого бюджету в тексті ст. 10 і розділу ХІІ Податкового кодексу України (ПКУ). Наголошено на помил­ковості законодавчого визначення одного податку складовою частиною або формою іншого податку (згідно з ПКУ плата за землю є часткою податку на майно, її фор­мами – земельний податок, оренд­на плата за земельні ділянки держав­ної та комунальної власності). У тексті ст. 273 розділу ХІІ ПКУ від­значено податок на лісові землі, відсутній в імпе­ративному списку місцевих податків і серед частин податку на майно. Помічено, що до його складу входять один місцевий податок (земельний) й один загальнодержавний обовʼязковий податковий платіж (рентна плата). Виявлено, що ступінь урегульованості обовʼязкових елементів плати за землю, земельного податку, орендної плати не повною мірою відповідає вимогам п. 7.1 ст. 7 ПКУ. Доведено, що зміст розділу ХІІ ПКУ (в частині оподаткування землі) не узгоджено з положен­нями ст. 10, 15, 22 цього правового акта. Сьо­годні в Україні справляються земельний податок й орендна плата, обовʼязкові елементи яких потребують негайного упорядкування. Вживане у тексті ПКУ словосполу­чення "плата за землю" належить трактувати як назву підгрупи обовʼяз­кових безумовних платежів до місцевого бюджету, що справляються з власників земельних ділянок та землекористувачів, яка входить до складу групи "Податки на майно".
The Performance of Pakistani Equity Mutual Funds During Bull and Bear Market
Authors: Yousif Muhammad , Ziaullah Muhammad , Tariq Muhammad Gulraiz
Published: February 2024

This study examines equity mutual funds in Pakistan within bull and bear market contexts.It traces the evolution and significance of mutual funds, particularly their adoption by investors for retirement and financial goals. Despite a substantial presence of open-ended and closed-ended mutual funds, Pakistan's mutual fund industry remains comparatively small on a global scale. Equity mutual funds, focused on stocks, appeal to young investors seeking higher returns with moderate risk. These funds enable risk diversification and effective portfolio management by experienced professionals. While small investors benefit from equity funds, their performance is subject to public scrutiny due to robust regulatory oversight. This research sheds light on equity mutual funds' role in Pakistan's financial landscape, emphasizing their importance in providing accessible and diversified investment options for a range of investors.
Optimized PID Controller of DC-DC Buck Converter based on Archimedes Optimization Algorithm
Authors: Fong Ling Kuok , Islam Muhammad Shafiqul , Ahmad Mohd Ashraf
Published: February 2024

This research assesses the suitability of the Archimedes Optimization Algorithm (AOA) as a metaheuristic technique to fine-tune a PID controller in a closed-loop DC-DC buck converter. The converter's core function is to regulate output voltage, ensuring stability despite load fluctuations and input voltage changes.  The operational effectiveness of the converter hinges significantly on the gain settings of the PID controller and determining the optimal gain setting for the PID controller is a non-trivial task. For robust performance, the PID controller necessitates optimal gain settings, attainable through metaheuristic optimization. The algorithm aids in identifying ideal proportional, integral, and derivative gains based on varying load conditions. Leveraging the metaheuristic algorithm, the PID controller is optimized to minimize voltage errors, reduce overshoot, and enhance response time. The proposed PID controller, optimized using AOA, is contrasted with PID controllers tuned via alternative algorithms including the hybrid Nelder-Mead method (AEONM), artificial ecosystem-based optimization (AEO), differential evolution (DE), and particle swarm optimizer (PSO). Performance evaluation involves injecting a voltage disturbance into the buck converter with load changes of up to 20%. Results demonstrate the superiority of the AOA-optimized PID controller in voltage recovery.  It demonstrates a faster response time and outstanding voltage regulation performance, while also exhibiting minimal performance degradation during load changes. This study concludes that the AOA optimization algorithm surpasses other methods in tuning the PID controller for closed-loop DC-DC buck converters.
A Review on Microgrids for Remote Areas Electrification-Technical and Economical Perspective
Authors: Khatun Erona , Hossain Md. Momin , Ali Md. Sumon , Halim Md. Abdul
Published: February 2024

The main objective of this study is to review microgrids from both a technical and financial standpoint in order to electrify rural places. Making a microgrid in rural area is challenging due to its technical and economical perspective. Technical and Economic analysis could investigate power quality and system stability for a local community in a nation. The technical and economic aspects of microgrid design and operation are covered, along with a number of other parts such power sources, energy storage, and control systems. Installation and maintenance cost has been discussed with respect to technological and economical view point in this paper. The report ends with a review of the prospects and problems for implementing microgrids in remote locations. Various challenges of microgrid and prospective solutions have also been discussed for the betterment of microgrid technically and economically. Microgrid planning has also been explained in this paper in rural regions entails the process of creating, developing, and deploying microgrid systems to provide dependable and sustainable power. Some influential factors such as technological factors, economic factors, socio-political factors and environmental factors on which microgrid depends have been discussed in this paper. The study offers a thorough discussion of microgrids as a potential method for electrifying rural areas. The study shows that microgrid is economically more beneficial to be developed in any rural area, as well as complying the minimum technical requirement of local grid code. Therefore, it can be said that any locality of a nation is a more viable and economic location to implement microgrid for the development. This review will assist the decision-makers in adopting microgrids for the electrification of rural areas and hold establishing regulations that are helpful and clear for the operation and integration of microgrids. System effectiveness, energy storage, and grid management breakthroughs may result from research and development of microgrid technology.
Nonmedication Devices in Development for the Treatment of Alzheimer’s Disease
Authors: Sleem Tamara , Decourt Boris , Sabbagh Marwan N.
Published: February 2024

Huge investments continue to be made in treatment for Alzheimer’s disease (AD), with more than one hundred drugs currently in development. Pharmacological approaches and drug development, particularly those targeting amyloid-β, have dominated the therapeutic landscape. At the same time, there is also a growing interest in devices for treating AD. This review aimed to identify and describe devices under development for AD treatment. In this review, we queried the devices that are in development for the treatment of AD. PubMed was searched through the end of 2021 using the terms “device,” “therapeutics,” and “Alzheimer’s” for articles that report on devices to treat AD. Ten devices with 31 references were identified as actively being developed for the treatment of AD. Many of these devices are far along in development. Device-based therapies are often overlooked when evaluating treatment approaches to AD. However, many devices for treating AD are in development and some show promising results.
Culture-Fair Cognitive Screening Tools for Assessment of Cognitive Impairment: A Systematic Review
Authors: Chithiramohan Tamara , Santhosh Smrithi , Threlfall Grace , Hull Louise , Mukaetova-Ladinska Elizabeta B. , Subramaniam Hari , Beishon Lucy
Published: February 2024

Background:

Cognitive screening tools are important in the detection of dementia, including Alzheimer’s disease; however, they may contain cultural biases.

Objective:

This review examines culture-fair cognitive screening tools and evaluates their screening accuracy, strengths, and limitations.

Methods:

Medline, Embase, PsychINFO and CINAHL were searched. The protocol was registered on PROSPERO (CRD42021288776). Included studies used a culture-fair tool to assess cognition in older adults from varying ethnicities. Narrative synthesis was conducted.

Results:

28 studies were included assessing eleven different tools. The Rowland Universal Dementia Assessment Scale (RUDAS) was as accurate as the Mini-Mental State Examination (MMSE) (AUC 0.62-0.93), with a similar sensitivity (52–94%) and better specificity (70–98%), and the Multicultural Cognitive Examination (MCE) had improved screening accuracy (AUC 0.99) compared to RUDAS (AUC 0.92). The Visual Cognitive Assessment Test (VCAT) was equivalent to MMSE (AUC 0.84–0.91). The Kimberley Indigenous Cognitive Assessment tool (KICA) had AUC of 0.93–0.95; sensitivity of 90.6%, specificity 92.6%.

Conclusions:

The RUDAS, KICA and VCAT were superior to MMSE for screening dementia in ethnic minorities. Other tools also showed good screening accuracy. Further research should be done to validate tools in different populations.
Clinicopathological analysis of 38 male patients diagnosed with breast cancer
Authors: Sahin Seniha Irem , Balci Serdar , Guler Gulnur , Altundag Kadri
Published: February 2024

BACKGROUND: Male breast cancer (MBC) accounts for one percent of all breast cancers. Due to the lack of awareness and routine screening programs, most patients present with systemic disease at the time of diagnosis with low overall survival. OBJECTIVES: This study aims to investigate the prognostic factors of male breast cancer and its correlation with established prognostic parameters and patient outcomes. METHODS: Thirty-eight male breast cancer patients are identified from the MKA Breast Cancer Clinic database, and their corresponding clinical and pathological characteristics are obtained. Cut-off values of 1% and 10% are applied to further classify ER and PR results. RESULTS: Older men are more likely to develop MBC than younger men and are more likely to have spread to axillary lymph nodes. Invasive ductal carcinoma is a more common histologic type in MBC. All the tested patients have ER and PR positivity. Distant metastasis developed in 17/38 (44.7%) patients. Bone metastasis is seen commonly in metastatic MBC. CONCLUSIONS: According to our cohort, MBC is seen in older males, presents in later stages, and shows hormone receptor positivity and a tendency to bone involvement. MBC is a heterogenous but distinct biological entity requiring a specific clinical and pathological approach.
Noninvasive Tests for Bladder Cancer Detection and Surveillance: A Systematic Review of Commercially Available Assays
Authors: Heard John R. , Mitra Anirban P.
Published: February 2024

BACKGROUND:

An important reason for the high health care costs associated with bladder cancer is the need for frequent cystoscopy for detection and surveillance of this disease. Cytologic analysis of voided urine specimens can assist, but is too inaccurate to replace cystoscopy. In an effort to create reliable, objective, noninvasive mechanisms for detecting bladder cancer, a number of urine-based molecular tests have been developed with the ultimate goal of reducing the frequency of cystoscopy.

OBJECTIVE:

To summarize the performance of urine-based biomarker tests, currently commercially available in the US, as part of the initial workup for hematuria and for bladder cancer surveillance.

METHODS:

In accordance with PRISMA guidelines we performed a systematic review of the literature on the performance of NMP22, BTA, UroVysion, ImmunoCyt/uCyt, CxBladder, and Bladder EpiCheck. Median sensitivity, specificity, negative (NPV) and positive predictive values (PPV) were calculated for each test based on the included studies.

RESULTS:

Twenty-eight studies met inclusion criteria for the performance of five urine-based biomarker tests in the setting hematuria workup. Median sensitivity ranged from 65.7% –100% and specificity ranged from 62.5% –93.8%. Median NPV ranged from 94.2% –98.3% and PPV ranged from 29% –58.7%. Fourteen studies met inclusion criteria for the performance of six tests in the setting of bladder cancer surveillance. Median sensitivity ranged from 22.6% –92.0% and specificity from 20.5% –97.9%. Median NPV ranged from 52.9% –96.5% and PPV ranged from 48.1% –75.7%.

CONCLUSIONS:

Our analysis finds that while these tests may provide some clinical utility, none of the assays have thus far demonstrated objective evidence to supplant the gold diagnostic standard.
Organizational learning capability: A bibliometric and content analysis based on Scopus data (1978–2023)
Authors: Lee Chin Tay , Lee Chee Tay
Published: February 2024

BACKGROUND:

Organizational learning capability research has been gaining more attention.

OBJECTIVE:

Specifically, this paper examines annual trend publication, active journals, authors, institutions, nations, keywords, citation pattern and top cited articles over the past 45 years. It decides the frequent organizational learning capability topics and highlights future research directions.

METHODS:

A bibliometric was performed on 149 papers published between 1978–2023 from the Scopus database. A content analysis was also performed.

RESULTS:

Publication trends have exhibited growth over time. Learning Organization and Industrial Marketing Management are two key journals that publish organizational learning capability. Publications are contributed by Chiva, R. and Alerge, J. Universidad Jaume I and Universitat de València are the two main institutions that exert the influence over the publication. Spain has been contributing more publications. Citations pattern analysis revealed 158.78 citations per year and 7145 citations for 149 papers. Sixthly, publications use keywords such as “organizational learning”, “innovation”. Both highly cited articles accumulated 442 citations.

CONCLUSIONS:

The findings are useful for policy-makers seeking reference and evidence to guide them in designing organizational learning capability policies, implementing management actions and programs.
RETRACTED: Study on cluster centers optimization of max-min distance k-means clustering algorithm based on inter-cluster separation measure
Authors: Xie Wenhao , Lei Lin , Liu Xiangyi , Liu Yuan
Published: February 2024

This article has been retracted. A retraction notice can be found at https://doi.org/10.3233/JIFS-219433.
Multi-mechanism neural machine translation framework for automatic program repair
Authors: Cao Heling , Han Dong , Chu Yonghe , Tian Fangchao , Wang Yun , Liu Yu , Jia Junliang , Ge Haoyang
Published: February 2024

Automatic program repair (APR) is crucial to improve software quality. Recently, neural machine translation (NMT) based modeling for bug fixes has demonstrated great potential. However, these approaches still have two major challenges. One is that their search space is limited due to the out-of-vocabulary (OOV) problem. The other is that the NMT-based APR models tend to ignore past translation information, which often leads to over-translation and under-translation. To address the above challenges, we propose MNRepair, a new NMT-based APR approach that combines multiple mechanisms to fix bugs in source code. Specifically, we devise an encoder-decoder NMT framework with the attention mechanism. Our framework combines the copy mechanism to overcome the OOV problem that occurs with source code. To deal with the over-translation and under-translation, we utilize a coverage mechanism to record past translation information. MNRepair is able to capture a wide range of repair operators and fix 26 bugs in Defects4J. Our evaluation shows the effectiveness of multiple mechanisms in the repair process.
A robust internal model control design for low-quality waste heat power generation systems
Authors: Xiao Yanjun , Li Shifang , Zhang Kun , Zhang Yameng , Xiao Yanchun
Published: February 2024

Recovering low-quality waste heat using industrial waste heat is challenging, and the reuse technology needs to erupt. Moreover, the gas source of low-quality waste heat is relatively volatile, which makes it challenging to keep the actual working condition of the plant stable. Therefore, it is inspiring to research the robustness of root-waste heat power generation processed measurement and control system to improve the stability of the plant operation. Hence, in this paper, we have applied uncertainty theory to analyze it and formulate the uncertainty model based on the Bode diagram. We also proposed a control method based on the uncertainty model, which combines robust control and internal model control to make the roots waste heat power generation system operate stably under the effect of external disturbances and changes of internal structure or parameters in actual operation. Experimental results show that the robust internal model control method has a speed deviation of no more than 7.9 r/min compared with the PID control method. The adjustment time to track the set value does not exceed 73.1 seconds within the allowed fluctuation range. The fluctuation variance is 30.95% of that of the PID controller. The dynamic performance is better, with strong anti-interference capability and significantly improved tracking performance. It ensures the stability of the roots-type waste heat utilization system, which is essential for future intelligent grid-connected power generation.
Exponential similarity measure of confidence consistency fuzzy cubic sets in fuzzy multiset scenarios and its application in piano performance evaluation
Authors: Niu Lu , Ye Jun
Published: February 2024

A consistency fuzzy set is composed of mean values and consistency degrees of fuzzy sequences in the transformation process of a fuzzy multiset (FM), but lacks confidence intervals in relation to a confidence level of fuzzy sequences, which shows its deficiency. To solve this deficiency, this paper aims to propose an improved transformation approach from FM to a confidence consistency fuzzy cubic set (CCFCS) and to develop an exponential similarity measure of CCFCSs for modeling piano performance evaluation (PPE) in a FM scenario. Consequently, this study includes the following context. First, a transformation approach from FM to CCFCS is proposed in terms of mean values, consistency degrees (the complement of standard deviation), and confidence intervals of fuzzy sequences subject to a confidence level and normal distribution. Second, the exponential similarity measure of CCFCSs is proposed in the scenario of FMs. Third, a PPE model is developed based on the proposed similarity measure of CCFCSs in the FM scenario. Finally, the developed model is applied to a piano performance competition organized by Shaoxing University in China as an actual evaluation example, and then the rationality and validity of the proposed model in the scenario of FMs are verified through sensitivity and comparison analysis.
RETRACTED: A research on an improved fuzzy approximate entropy algorithm for EMG-based shoulder and neck muscle fatigue detection
Authors: Hou Yuntong , Shang Shuye , Cao Shengxi , Liu Zhengjia
Published: February 2024

This article has been retracted. A retraction notice can be found at https://doi.org/10.3233/JIFS-219433.
Treatment of Symptomatic Spinal Muscular Atrophy with Nusinersen: A Prospective Longitudinal Study on Scoliosis Progression
Authors: Ip Hoi Ning Hayley , Yu Michael Kwan Leung , Wong Wilfred Hing Sang , Liu Amanda , Kwan Kenny Yat Hong , Chan Sophelia Hoi Shan
Published: February 2024

Background:

Nusinersen treatment has demonstrated efficacy in improving clinical outcomes for spinal muscular atrophy (SMA), yet its impact on scoliosis progression remains unclear.

Objective:

This study aimed to assess the progression of scoliosis in pediatric patients with SMA undergoing nusinersen treatment.

Methods:

In this prospective study, data were systematically collected from Hong Kong pediatric SMA patients receiving nusinersen between 2018 and 2023. All patients had longitudinal radiographic studies pre-nusinersen, and at half-yearly or yearly intervals during treatment based on the scoliosis severity. Motor function evaluations were conducted pre-nusinersen, and after starting treatment at 6- and 12-month intervals.

Results:

Twenty-three patients ((SMA type 1 (SMA1) = 8, SMA type 2 (SMA2) = 7, SMA type 3 (SMA3) = 8)) with a median age of 5.8 years (range: 0.4–17.5 years) at nusinersen initiation, and median follow-up duration of 3.4 years (range: 1.1–5.2 years) were included. During the study period, motor scores remained stable or improved in 83% of patients. However, scoliosis progressed across all subtypes, with mean annual progression rates of 5.2, 11.9, and 3.6 degrees in SMA1, SMA2, and SMA3 respectively. Patients initiating nusinersen between ages 5 and 11 years exhibited the most rapid progression, with rates of 11.8, 16.5, and 7.3 degrees per year in SMA1, SMA2, and SMA3 respectively. Positive correlations were observed between the difference in CHOP-INTEND score post-nusinersen and scoliosis progression in SMA1 (rs = 0.741, p = 0.041). Conversely, negative correlations were found between the difference in HFMSE score post-nusinersen and scoliosis progression in SMA2 (rs =−0.890, p = 0.012) and SMA3 (rs =−0.777, p = 0.028).

Conclusions:

This study reveals that nusinersen treatment in symptomatic pediatric SMA patients with motor improvement is linked to increased scoliosis progression in SMA1, whereas it is associated with decreased progression in SMA2 and SMA3. Age, baseline Cobb angle, and motor milestone improvement are influential factors in scoliosis progression.
Identifying Subtle Motor Deficits Before Parkinson’s Disease is Diagnosed: What to Look for?
Authors: Maetzler Walter , Mirelman Anat , Pilotto Andrea , Bhidayasiri Roongroj
Published: February 2024

Motor deficits typical of Parkinson’s disease (PD), such as gait and balance disturbances, tremor, reduced arm swing and finger movement, and voice and breathing changes, are believed to manifest several years prior to clinical diagnosis. Here we describe the evidence for the presence and progression of motor deficits in this pre-diagnostic phase in order to provide suggestions for the design of future observational studies for an effective, quantitatively oriented investigation. On the one hand, these future studies must detect these motor deficits in as large (potentially, population-based) cohorts as possible with high sensitivity and specificity. On the other hand, they must describe the progression of these motor deficits in the pre-diagnostic phase as accurately as possible, to support the testing of the effect of pharmacological and non-pharmacological interventions. Digital technologies and artificial intelligence can substantially accelerate this process.
Synthesis of nitrogen-doped graphene coupled acid fuchsin photocatalyst turns aryl-vinyl into aromatic aldehydes under visible light
Authors: Manish  , Yadav Rajesh K. , Singh Satyam , Shahin Rehana , Singh Chandani , Nayak Ripsa Rani , Singh Atul P. , Tiwary Dhanesh , Kumar Pramod , Baeg Jin OoK , Gupta Navneet Kumar
Published: February 2024

A schematic strategy is presented to overcome the problem of low photocatalytic performance of graphene. Herein, we synthesized nitrogen-doped graphene (NDG)-coupled acid fuchsin (AF) photocatalyst, i.e.; NDGCAF photocatalyst. The NDGCAF photocatalyst has excellent solar light harvesting ability, band gap suitability, and high molar extinction coefficient than the NDG photocatalyst. Due to these properties, the NDGCAF photocatalyst has the ability to oxidize aryl-vinyl into aryl-vinyl-aldehyde under the irradiation of visible light. In this context, it exhibited the utmost conversion efficiency of aryl-vinyl to aryl-vinyl-aldehyde with a good yield of 98.15%. Current research highlights the significant application of NDGCAF light-harvesting photocatalysts in the research field of organic transformations.
Data aggregation and routing in Mobile Ad hoc network: Introduction to Self-Adaptive Tasmanian Devil Optimization
Authors: Y Kingston Albert Dhas , Jerine S.
Published: February 2024

Mobile Ad-Hoc Network (MANETs) is referred to as the mobile wireless nodes that make up ad hoc networks. The network topology may fluctuate on a regular basis due to node mobility. Each node serves as a router, passing traffic throughout the network, and they construct the network’s infrastructure on their own. MANET routing protocols need to be able to store routing information and adjust to changes in the network topology in order to forward packets to their destinations. While mobile networks are the main application for MANET routing techniques, networks with stationary nodes and no network infrastructure can also benefit from using them. In this paper, we proposed a Self Adaptive Tasmanian Devil Optimization (SATDO) based Routing and Data Aggregation in MANET. The first step in the process is clustering, where the best cluster heads are chosen according to a number of limitations, such as energy, distance, delay, and enhanced risk factor assessment on security conditions. In this study, the SATDO algorithm is proposed for this optimal selection. Subsequent to the clustering process, routing will optimally take place via the same SATDO algorithm introduced in this work. Finally, an improved kernel least mean square-based data aggregation method is carried out to avoid data redundancy. The efficiency of the suggested routing model is contrasted with the conventional algorithms via different performance measures.
Visualization as a trend of forms of culture and communication
Authors:   International University of Information Technology, Beisenkulov A.A. , Zharylgap Zh.D. ,   Al-Farabi Kazakh National University, Sadyrova S.Sh. ,   Al-Farabi Kazakh National University
Published: February 2024

The topic of information visualization in modern mass media has become one of the hottest topics in the science of journalism in recent years. In this paper, a classification of the visualization of journalistic material is proposed: the design of an online publication, illustrations, photographs, infographics, and various forms of multimedia content characterize the trends of their development. Visual effects are applicable not only to print media but also to television and Internet media. The digital revolution is characterized by the emergence of new and the evolution of previously known forms of visualization. In particular, television and Internet media have gained great advantages in terms of the possibilities of technical solutions and visual forms of displaying content
Mobilography is a new phenomenon in the media
Authors:   Akhmet Yassawi International Kazakh-Turkish University, Serdali B.
Published: February 2024

Today's media not only spread information, but also create interesting news that we can watch, listen to and read by viewing our audiovisual creations using our small mobile devices. This trend usually coincides with modern searches in the media sphere. Therefore, mobile journalism is gaining momentum not only abroad, but also in Kazakhstan. Young journalists who are passionate about the possibilities of new media, and those who want to work in the field of media in the future, react especially to this. They prove that, as before, there is no need to sit in front of large portable computers, monitors. Through their small mobile devices in their hands, they can shoot, edit and create high-quality media products. Our article says that mobilography is one of such modern phenomena. We can say that this is a new direction in electronic journalism. At first it appeared as a genre of photography and in a short time gained popularity among millions of amateur photographers. And this was followed by skeptical interest, creating an image among photography professionals. Now, in this process, television filming has also begun to be done.
Comparison of information security methods of information-communication infrastructure: Multi-Factor Authentication
Authors: Safin R. , Abdiraman A. , Nurusheva A. , Aldasheva L.
Published: February 2024

Sensitive information was always one of the big trade-offs we always exchange big secrets for small ones. On one hand, memorization of small secrets on the other hand tons of services requires a dedicated secret for each one. And when one of the services will be compromised it affects all services with the same password and credential. The main purpose of this article is to discuss multiple factors and increase security trade-offs differently. We will try to compare MFA (Multi-Factor Authentication), 2FA (Two Factor Authentication), 2SV (Two-Step Verification), and 1FA (One Factor Authentication) and investigate the password-free future.
Gambaran Infeksi Soil Transmitted Helminth pada Petani Penyitas Erupsi Gunung Semeru
Authors: Rohmayani Vella Rohmayani, , Arimurti Anindita Riesti Retno , Sari Yeti eka Sispita , Romadhon Nur Hidayatullah , Lihabi Libahi
Published: February 2024

Latar belakang: Soil Transmitted Helminth (STH) adalah cacing golongan Nematoda usus yang siklus penularannya membutuhkan tanah. Tujuan: untuk mengetahui gambaran infeksi parasit STH pada kuku tangan petani penyintas erupsi gunung Semeru di desa Sumbermujur kecamatan Candipuro kabupaten Lumajang. Metode: Desain penelitian cross sectional. Sampel penelitian adalah petani penyintas erupsi semeru sebanyak 25 orang. Pengumpulan data menggunakan metode wawancara dan pemeriksaan potongan kuku tangan di laboratorium untuk mengidentifikasi keberadaan telur parasit STH pada petani penyintas erupsi gunung Semeru. Sampel yang digunakan adalah kuku tangan petani penyintas erupsi Gunung Semeru. Pemeriksaan sampel di laboratorium menggunakan metode sedimentasi. Hasil: dari 25 sampel yang diperiksa ditemukan sebanyak 4 sampel atau sebesar 16% yang dinyatakan positif terinfeksi STH dan 4 sampel yang dinyatakan positif ditemukan 1 jenis parasit STH yaitu spesies Ascaris lumbricoides. Berdasarkan hasil uji Chi Square diperoleh Pvalue=0,03. Kesimpulan: ada hubungan antara kebersihan diri dengan keberadaan telur STH pada sampel kuku tangan petani.
ТРАНСРЕГІОНАЛЬНА СПІВПРАЦЯ ЯК ЧИННИК ПІДВИЩЕННЯ ІНСТИТУЦІЙНОЇ СПРОМОЖНОСТІ ПУБЛІЧНОГО ВРЯДУВАННЯ
Authors: Щербак В. М.
Published: February 2024

Розглядається інституційна спроможність, яка виступає одним із визначальних критеріїв дієвості та ефективності системи публічного врядування. Вивчається взаємодія інститутів публічної влади та місцевого самоврядування в рамках координації та організації трансрегіональної співпраці в умовах російсько-української війни. Розкривається специфіка транскордонної та трансрегіональної співпраці, яка вимагає усунення суттєвих перешкод щодо оптимізації управлінських дій. Встановлюються особливості вертикальної інтеграції публічного врядування, яка свідчить про системність відносин всередині системи публічного врядування. Аналізуються керівні документи зарубіжних країн, які вимагають розбудови інституційної спроможності. Встановлюється значення інституційної спроможності публічного врядування в контексті пріоритетів трансрегіональної співпраці. Досліджується автономна управлінська діяльність у різних секторах міжрегіональної співпраці, яка відображає бажання урядовців реалізовувати проєкти в рамках одночасного розв’язання багатьох завдань. З’ясовуються чинники корекції досвіду та практик міжрегіональної співпраці. Розкривається зміст перспективи взаємодії партнерства різних регіонів та транскордонного співробітництва, які вимагають однозначної оцінки результатів співпраці та їх цілей. Встановлено, що інституційна спроможність публічного врядування є вкрай необхідною в умовах технологічних інновацій. Досліджуються конкретні кейси розвитку сучасних регіонів, які засвідчують, що регіональне партнерство дедалі більше відокремлюється від національного порядку денного. З’ясовуються фактори інституалізації регіональної співпраці, які слугують потужним засобом виведення міждержавних відносин на новий рівень. Доведено, що в умовах російсько-української війни зростає значення державно-приватної та державно-громадської співпраці, яка дозволила значно підвищити оперативність ухвалення рішень щодо реалізації програми волонтерської допомоги та інших міжнародних громадських проєктів.
Increasing Access to Postsecondary Education as a Source of Empowerment for Black Youth In Ontario: With a Particular Focus on Science, Technology, Engineering and Mathematics (Stem) Programs
Authors: Turner Shenique
Published: February 2024

This study examines issues of educational access encountered by black youth in Ontario’s postsecondary education sector, with a particular focus on Science. Specifically, the paper explores racism and socioeconomic status as two main factors contributing to limitations encountered by racialized youth in their quest for academic access and excellence. To understand better the barriers affecting black youth in this context, the study engages Critical Race Theory as the framework for explaining the imbalanced educational opportunities and issues that limit educational access for racialized youth. Furthermore, this study offers policy options related to bridging programs, mentorship, de-streaming classrooms, and increasing funding, as instrumental in enhancing educational outcomes for black youth.
Skills Recognition for Immigrant Workforce Integration: Employer Centered Practices in Canada
Authors: Chatterjee Tuhina
Published: February 2024

Canada welcomes global talent and undertakes initiatives to integrate this talent into the domestic workforce. As of 2018, the largest share of immigrants that entered the country have come through the federal skilled worker's program (IRCC, 2019) that grants individual’s permanent residency in Canada on a points-based system evaluating skills, education background, work experience, language, adaptability, age, and arranged employment.

However, the receptibility and efficient integration of this talent, its diverse skills and experiences need to be reviewed from the macro lens of existing domestic systems like recognition of competencies beyond academic qualifications, licensing requirements, employer trust in international experience, and access to integrated information to make informed decisions.

In this paper, we shall focus on employer’s role in recognition and integration of immigrant talent by reviewing existing practices, identifying gaps and providing some recommendations for co-designing of immigrant integration systems.
The Evolution of the Ontario Poverty Reduction Strategy
Authors: Arbaji Sarah
Published: February 2024

Ontario released its first Poverty Reduction Strategy (PRS) in 2008. This paper will map out the development and evolution of the Ontario PRS in the context of the emergence of poverty reduction strategies more broadly. The neoliberal context out of which these poverty reduction strategies emerged will be explored. The conceptualization of poverty based on social inclusion and exclusion will also be discussed within the neoliberal era.
Developing the Voluntary Sector’s Policy Capacity: How Umbrella Organizations Can Bridge The Gap Between the Public and Voluntary Sectors – The Case of Imagine Canada
Authors: Alkarmi Summer
Published: February 2024

The purpose of this paper is to build on the research done by previous public and voluntary endeavours to strengthen the policy capacity of the voluntary sector. The paper will demonstrate that Imagine Canada, as a national umbrella organization, is well-positioned to develop the voluntary sector’s policy capacity at the national level, and foster a more collaborative relationship with the government. The challenges facing the voluntary sector are examined in this paper along with a brief history of government voluntary relations, overview of the voluntary sector and a rationale for Imagine Canada’s role in strengthening the policy capacity of the sector and formalizing the policy engagement process on a federal level.