bluuebunny/crossref_metadata_2025 huggingface dataset:
Assessment of Immune and Clinical Response in Patients with Mucosal Leishmaniasis Treated with Pentavalent Antimony and Pentoxifylline
Authors: Cincura Carolina , Costa Rubia S. , De Lima Clara Monica F. , Oliveira-Filho Jamary , Rocha Paulo Novis , Carvalho Edgar M. , Lessa Marcus M.
Published: November 2022

Mucosal leishmaniasis (ML) is a severe form of tegumentary leishmaniasis associated with a persistent inflammatory response. High levels of TNF, IFN-γ, CXCL9 and CXCL10 are found in ML patients, and the association of pentoxifylline with antimony is more effective in decreasing the healing time in ML patients when compared to antimony alone. The present study aimed to investigate the existence of a correlation between cytokine and chemokine production and ML severity and evaluate the potential value of cytokine and chemokine production as marker of therapeutic response in ML patients. This prospective study included 86 subjects in an area of endemic Leishmania braziliensis transmission. Patients diagnosed with ML were classified into clinical stages ranging from I to V according to disease severity. TNF, IFN-γ, CXCL9 and CXCL10 levels were quantified in the supernatant of the mononuclear cell cultures by ELISA before and after treatment with antimony alone or antimony plus pentoxifylline. The median TNF level in the group with mild disease (Stages I–II) was 1064 pg/mL (142–3738 pg/mL), while, in the group with moderate or severe disease (Stages III–V), it was 1941 pg/mL (529–5294 pg/mL) (p = 0.008). A direct correlation was observed between ML clinical severity and levels of TNF production (r = 0.44, p = 0.007). Patients who were treated with antimony and pentoxifylline healed significantly faster than those treated with antimony alone (52 vs. 77 days, hazard ratio = 0.60; 95% confidence interval = 0.38–0.95, p = 0.013). Therapeutic failure was higher in the group that received antimony alone (25% vs. 7%; p = 0.041). There was a significant decrease in CXCL9 after therapy of ML in both groups (p = 0.013; p = 0.043). TNF levels are associated with the severity of mucosal diseases, and pentoxifylline associated with antimony should be the recommended therapy for ML in countries where liposomal amphotericin B is not available.
Method and Practice for Integrated Water Landscapes Management: River Contracts for Resilient Territories and Communities Facing Climate Change
Authors: Rossi Francesca
Published: November 2022

The negative impacts of climate change on natural and anthropic ecosystems have led to the increasingly urgent search for policies, strategies and tools able to counteract degradation and risk factors on vulnerable landscapes. Among these, the research activity refers to water landscapes as a specific field of study that represents a fundamental resource for human well-being. In consistency with the international policy framework on integrated water management, this contribution develops a case study analysis focused on River Contracts as innovative, voluntary and negotiated planning practices aimed at the reconstruction of territorial, social and ecological values, which broaden the boundaries of safeguarding by integrating protection actions with sustainable management and environmental regeneration and to restore the identity of places and local communities. The description and evaluation of an ongoing experience of River, Coast and Landscape Contracts, developed along the coast of the Lazio region, allows one to point out that the process method is successful in solving complex issues related to the management of the river basin while involving social actors in order to improve people’s knowledge of the territory, increase social awareness of risk conditions, and allow local communities to propose and implement shared solutions. The results of this territorial and multi-level governance method are therefore measured on their capacity to produce territorial, social and environmental resilience.
Challenges and Opportunities for Global Genomic Surveillance Strategies in the COVID-19 Era
Authors: Ling-Hu Ted , Rios-Guzman Estefany , Lorenzo-Redondo Ramon , Ozer Egon A. , Hultquist Judd F.
Published: November 2022

Global SARS-CoV-2 genomic surveillance efforts have provided critical data on the ongoing evolution of the virus to inform best practices in clinical care and public health throughout the pandemic. Impactful genomic surveillance strategies generally follow a multi-disciplinary pipeline involving clinical sample collection, viral genotyping, metadata linkage, data reporting, and public health responses. Unfortunately, current limitations in each of these steps have compromised the overall effectiveness of these strategies. Biases from convenience-based sampling methods can obfuscate the true distribution of circulating variants. The lack of standardization in genotyping strategies and bioinformatic expertise can create bottlenecks in data processing and complicate interpretation. Limitations and inconsistencies in clinical and demographic data collection and sharing can slow the compilation and limit the utility of comprehensive datasets. This likewise can complicate data reporting, restricting the availability of timely data. Finally, gaps and delays in the implementation of genomic surveillance data in the public health sphere can prevent officials from formulating effective mitigation strategies to prevent outbreaks. In this review, we outline current SARS-CoV-2 global genomic surveillance methods and assess roadblocks at each step of the pipeline to identify potential solutions. Evaluating the current obstacles that impede effective surveillance can improve both global coordination efforts and pandemic preparedness for future outbreaks.
The Barretos Cancer Hospital Animal Facility: Implementation and Results of a Dedicated Platform for Preclinical Oncology Models
Authors: Teixeira Silvia A. , Luzzi Mayara de Cassia , Martin Ana Carolina Baptista Moreno , Duarte Terence Teixeira , Leal Mônica de Oliveira , Teixeira Gustavo Ramos , Reis Monise Tadin , Junior Carlos Roberto Almeida , Santos Karina , Melendez Matias Eliseo , Silva Diego da Cunha Silveira Alves da , Bernécule Priscila Neves , Firmino Higor Vinicius Lourenço , Alves Ana Laura Vieira , Guimarães Denise Peixoto , Borduqui João Vitor , Laus Ana Carolina , Mançano Bruna Minniti , Reis Rui Manuel
Published: November 2022

The Barretos Cancer Hospital Animal Facility (BCHAF) is a unique facility in Brazil exclusively dedicated to working with animal models for cancer research. In this article, we briefly present our modern facility and the main experiments performed, focusing on mutant strains of mice (PTCH-knockout and ApcMin mice), xenograft models, and patient-derived xenografts (PDXs). Our results show the progress and challenges in establishing these models and the need for having an appropriate representation of our cancer population to better understand tumor biology and to identify cancer biomarkers, which could be putatively targeted, allowing for personalized therapy.
The Use of Lime for Drainage of Cohesive Soils Built into Hydraulic Engineering Embankments
Authors: Połomski Maksymilian , Wiatkowski Mirosław
Published: November 2022

This paper examines whether lime can be used for the drainage of cohesive soils built into hydraulic engineering embankments. It is a common practice, as early as the planning stage, to seek to reduce costs and accelerate work while maintaining the quality of work. Although lime stabilisation is not currently a widely used solution in the hydraulic engineering sector, it can play an important role in the future. Lime stabilisation can be considered an optimal solution as it shortens the embankment construction by eliminating the need to replace the soil when it is over-wet. This paper investigates whether it is possible to apply lime treatment in the forming of hydraulic engineering embankments as well as analyses the efficiency of mechanical soil drainage and compares it against chemical drainage (lime stabilisation) based on the example of the construction of the Szalejów Górny dry flood control reservoir located in south-western Poland. It presents the results of geotechnical investigations carried out during the construction phase and compares them with cases reported in the literature. The observation of the construction process reveals a high efficiency and effectiveness of quicklime (CaO) as a stabiliser in the soil used for reservoir dams. Adoption of this technology made it possible to achieve significantly higher embankment formation rates (max. approx. 14,000 m3/week) than when mechanical drainage was used (max. approx. 11,000 m3/week). It was also noted that the lime stabilisation process was significantly independent of unfavourable weather conditions, resulting in frequent high weekly efficiencies. Geotechnical tests on samples of the lime-stabilised soil built into the dam body confirmed the possibility of obtaining favourable strength parameters, particularly with regard to the angle of internal friction, cohesion and degree of plasticity. Therefore, it can be expected that lime will be used more widely in the formation of hydraulic engineering embankments and that soil stabilisation technology will be applied more frequently.
Remote Sensing Retrieval of Total Nitrogen in the Pearl River Delta Based on Landsat8
Authors: Guo Yu , Deng Ruru , Li Jiayi , Hua Zhenqun , Wang Jing , Zhang Ruihao , Liang Yeheng , Tang Yuming
Published: November 2022

The Pearl River Delta in South China is subject to severe eutrophication, which is significantly exacerbated by the total nitrogen (TN). Remote sensing technology with large-scale synchronous observations in the Pearl River Delta can effectively monitor organic pollution. Statistical methods based on remote sensing images have been widely used in water quality parameter retrieval for inland rivers, reservoirs, and lakes, but have seldom been applied in the Pearl River Delta. TN is also a non-optically active substance, so it is difficult to retrieve TN through analysis methods. This study retrieves the concentration of total nitrogen (TN) based on Landsat8 images of the Pearl River Delta using a statistical method. The stepwise regression function is built by analyzing the TN concentration and the single-band, two-band, and three-band spectral information groups measured by an ASD FieldSpec3 spectrometer. The retrieval results show that the proposed method performs well with a small mean absolute error (MAE) (0.36 mg/L for TN) and high agreement (R2 = 0.61 for TN) between the in situ data and the retrieval concentration. The results demonstrate that the concentration of TN in the east of the Pearl River Delta was higher than in the west. Dachan Bay and Shenzhen Bay had the highest TN concentrations, which were around 3.02 mg/L and 3.67 mg/L. The 750–850 nm band could be an important reference for further exploring the spectral characteristics and retrieval of TN. The retrieval method in this study is easy to implement and convenient for local TN distribution capture, which can provide a timely reference for daily water quality supervision and management in the Pearl River Delta.
A Modified Two-Parameter Monthly Water Balance Model for Runoff Simulation to Assess Hydrological Drought
Authors: Hong Xingjun , Guo Shenglian , Chen Guiya , Guo Na , Jiang Cong
Published: November 2022

Quantitative assessment of the frequency and magnitude of drought events plays an important role in preventing drought disasters and ensuring water security in river basins. In this paper, we modified a parsimonious two-parameter monthly water balance (TPMWB) model by incorporating the generalized proportionality hypothesis with precipitation and potential evapotranspiration as input variables. The modified TPMWB was then used to simulate the monthly hydrological processes of 30 sub-basins in the Han River basin. It is shown that the water balance model can satisfactorily simulate the hydrological regimes in the selected sub-basins. We derived the probability distribution functions of monthly runoff using the principle of maximum entropy to calculate the Standardized Runoff Index (SRI), and assessed the historical hydrological drought conditions. By investigating the correlation between four major drought characteristics (i.e., drought duration, drought severity, drought intensity, and drought inter-arrival time) and four dimensionless parameters representing the climatic and underlying properties of the basin, a conclusion can be drawn that the formation and development of hydrological drought in the Han River basin is mainly controlled by watershed storage factors, and the influence of climatic factors is also significant. The proposed approach provides a potential alternative for regional drought early warning and under changing environmental conditions.
Improving Lake Level Prediction by Embedding Support Vector Regression in a Data Assimilation Framework
Authors: Wang Kang , Hu Tengfei , Zhang Peipei , Huang Wenqin , Mao Jingqiao , Xu Yifan , Shi Yong
Published: November 2022

Data-driven models are widely used in the field of water level prediction due to their generalizability and predictive abilities. In long-series prediction, however, data-driven models degrade rapidly due to the uncertainty and constraints of model data and parameters. To address the problem of inaccurate continuous water level prediction, this study introduced a data assimilation technique, the unscented Kalman filter (UKF), and embedded support vector regression (SVR) into the framework and applied it to Dongting Lake, the second largest freshwater lake in China. The results demonstrated that the assimilation model is significantly better than the non-assimilation model in predicting water levels and is not affected by the characteristics of lake level changes, with the R2 increasing from 0.975–0.982 to 0.998–0.999 and the RMSE decreasing from 0.436–0.159 m to 0.105–0.042 m. The prediction lead time also increased with the increase of continuous assimilation data. Further analysis of the assimilation model showed that when there was an assimilation cycle, the prediction remained stable for successive sets of two or more assimilated data, and the prediction lead time increased with successive assimilated data, from 4–8 days (one successive assimilation data) to 9–12 days (five successive assimilation data). Overall, this study found that the data assimilation framework can improve the prediction ability of data-driven models, with assimilated models having a smaller fluctuation range and higher degree of concentration than non-assimilated models. The increase in assimilated data will improve model accuracy as well as the number of days of prediction lead time when an assimilation cycle exists.
Educational and practical room as a system element of continuous professional development of nursing staff
Authors:   MBI Central City Clinical Hospital No. 6, Yekaterinburg, Russia, Bernatovich O. A.
Published: November 2022

Modernization and innovative improvement of the healthcare industry determine the need to form a new model of nursing specialists with professional knowledge, able to flexibly restructure their professional activities. Continuous personnel training at the workplace allows a medical organization to solve problems associated with the emergence of new areas of activity, be patient-oriented, and maintain the necessary level of competitiveness.
Advance care planning engagement in patients with chronic, life-limiting illness: baseline findings from a cluster-randomised controlled trial in primary care
Authors: Stevens Julie , Miranda Rose , Deliens Luc , Pype Peter , De Vleminck Aline , Pardon Koen
Published: November 2022

Background

Advance care planning (ACP) has been characterised as a complex process of communication and decision making. For ACP behaviour change, underlying processes such as self-efficacy and readiness are needed. However, studies about which patient characteristics are associated with ACP have mainly focused on whether ACP actions are completed, leaving behaviour change processes unexplored.

Aim

To assess whether patients’ characteristics and patient-perceived quality of GP ACP communication were associated with patients’ ACP engagement.

Design and setting

Baseline data were used from the ACP-GP cluster-randomised controlled trial in patients with chronic, life-limiting illness (n= 95).

Method

Patients completed questionnaires detailing demographic and clinical characteristics, and their perception about their GPs’ ACP information provision and listening. Engagement was measured using the 15-item ACP Engagement Survey, with self-efficacy and readiness subscales. Linear mixed models tested associations with engagement.

Results

Demographic and clinical characteristics were not associated with engagement; nor was how much ACP information patients received from their GP or the extent to which the GP listened to what was important for the patient to live well or important to the patient regarding future care. Higher overall ACP engagement (P= 0.002) and self-efficacy (P<0.001) were observed in patients who gave a high rating for the extent to which their GP listened to their worries regarding future health.

Conclusion

This study suggests that GPs providing information about ACP alone is not associated with a patient’s ACP engagement; an important element is to listen to patients’ worries regarding their future health.
Home monitoring by pulse oximetry of primary care patients with COVID-19: a pilot randomised controlled trial
Authors: Smit Karin , Venekamp Roderick P , Krol Loeke A , Geersing Geert-Jan , Schoonhoven Lisette , Kaasjager Karin AH , Rutten Frans H , Zwart Dorien LM
Published: November 2022

Background

Pulse oximetry as a home or remote monitoring tool accelerated during the pandemic for patients with COVID-19, but evidence on its use is lacking.

Aim

To assess the feasibility of home monitoring by pulse oximetry of patients aged ≥40 years with cardiovascular comorbidity and moderate-to-severe COVID-19.

Design and setting

A primary care-based, open, pilot randomised controlled trial, with nested process evaluation, was undertaken in the Netherlands.

Method

From November 2020 to June 2021, eligible patients presenting to one of 14 participating Dutch general practices were randomly allocated to regular measurement of peripheral oxygen saturation (at least three SpO2measurements per day for 14 days) with a validated pulse oximeter or usual care.

Results

All 41 participants (21 intervention, 20 usual care) completed the 45-day follow-up period. Overall, the intervention group performed 97.6% of protocolised measurements; the median daily measurement per participant was 2.7 (interquartile range 1–4). Hypoxemia (SpO2<94%) was reported in 10 participants (in 52 measurements); of those, six consulted the GP as instructed. Participants reported a high feeling of safety (0–100 visual analogue scale): 71.8 for the intervention group versus 59.8 for the control (P= 0.09). Primary care consultations were similar across groups: 50 for the intervention versus 51 for the control. Eleven visits by 10 participants were made to the emergency department (eight from the intervention group versus three from usual care), of which six participants were hospitalised (five intervention versus one usual care). No participants were admitted to the intensive care unit or died during follow-up.

Conclusion

Home monitoring of patients with moderate-to-severe COVID-19 by pulse oximetry appeared feasible; adherence was high, patients reported a high feeling of safety, while the number of primary care consultations remained similar to usual care.
Planejamento online de caminhos por cobertura através de meta-heurística
Authors:   , Biundini Iago Zanuti
Published: November 2022

Diferentes aplicações práticas com Veículos Aéreos Não Tripuláveis (VANTs) surgiram nos últimos anos, exigindo inspeções periódicas e detalhadas para verificar possíveis alterações estruturais. As inspeções usando veículos aéreos não tripulados VANTs devem minimizar o tempo de voo devido às restrições de tempo da bateria e identificar as características topográficas do terreno ou estruturas. Nesse sentido, o Planejamento do Caminho de Cobertura (CPP) visa encontrar o melhor caminho para a cobertura de uma determinada área respeitando as restrições da operação. As informações fotométricas do terreno são usadas para criar rotas ou mesmo refinar caminhos já criados, além de possibilitar diversos tipos de análises de imagens. Portanto, a principal contribuição desta pesquisa é o desenvolvimento de uma metodologia que utiliza um algoritmo meta-heurístico para criar missões otimizadas que buscam equilibrar dois objetivos conflitantes: tempo da missão e qualidade das imagens visando reconstruções 3D. A técnica foi aplicada tanto em um cenário simulado quanto em um ambiente real para verificar sua eficácia, buscando a aplicação de diversas técnicas meta-heurísticas e uma análise estatística sobre os resultados encontrados. Além disso o algoritmo foi aplicado nos mais diversas estruturas, tanto em taludes como em regiões a serem investigadas, através de sensores ativos como Lasers e mapas fornecidos de maneira offline através de point cloud e digital elevation model. Os resultados mostraram que o algoritmo foi capaz de criar missões otimizadas, equidistante a superfície e com todos os critérios de CPP sendo atendidos com equilíbrio dos objetivos de tempo e fotometria em comparação com outros algoritmos. Além disso, existe a possibilidade de controlar os dois objetivos propostos, visando aumentar a qualidade da reconstruções tridimensional e o tempo da missão.
Residir escola, nomadizar arte
Authors:   , Oliveira Bruna Tostes de
Published: November 2022

Residir gestos, residir textos, residir formas, residir linguagens, residir apagar, residir distanciar, residir desviar, residir sobras, residir dobras, residir meios, residir escolas, residir ocupar, residir ver, residir cegar, residir imagens, residir territórios, residir casas, residir templos, residir museus, residir passagens, residir aprender, residir desaprender,residir abrigar, residir vacilar, residir travessias, residir caos, residir pesquisa menor, residir experimentar, residir ação, residir vida. Residir afetos, residir perceptos, residir professores (as), residir artistas, residir curadores, residir mediadores, residir estudantes, residir diretores, residir mães, residir pesquisadora, residir sensações. Que residir? Nomadizar. Não fixar, transmutar, desterritorializar e territorializar, esquecer, perder memória, ficar com o jorro de traços de expressões dos gestos, dos sons, das cores e das posturas.
Mulheres de pés descalços e pulsos fortes, mulheres de terreiro: estudo de caso sobre identidades e experiência religiosa no Ilê Axé Egun (Juiz de Fora/MG)
Authors:   , Rabello Kelly
Published: November 2022

As religiões de matriz africana, de modo geral, evidenciam uma centralidade à figura da mulher, o que pode ser percebido tanto em sua mitologia quanto nas práticas que são vivenciadas dentro dos terreiros. Todavia, o intuito dessa pesquisa é identificar não apenas como as mulheres se inserem no campo afro-religioso, mas, sobretudo, como a religião se insere na vida dessas mulheres. Portanto, o objetivo geral dessa tese pauta-se em compreender as experiências religiosas de mulheres que ocupam os cargos de Iyalorixá, iyabassé, ekede e médiuns no Ilê Axé Egun, investigando como essas experiências com o sagrado atravessam as suas trajetórias de vida e corroboram na formação de suas identidades pessoais e coletivas. Para tanto, a fim de contextualizar o tema, foi realizada uma revisão bibliográfica sobre o campo das religiões afro-brasileiras, e, ainda, sobre a forma como os aspectos femininos são abordados e valorizados no mundo dos Orixás, assim como foi discutido o papel singular das mulheres na história de formação das comunidades de terreiro no Brasil. Por fim, para se responder ao objetivo central dessa pesquisa, foi adotada a metodologia qualitativa. Desse modo, foi desenvolvida a observação participante nas sessões públicas do Ilê Axé Egun e foram aplicadas entrevistas semiestruturadas com seis mulheres que exercem diferentes funções na casa. A finalidade das entrevistas foi compreender como a experiência religiosa está presente em suas vidas, sendo possível constatar nas narrativas que os laços criados com as Entidades, Orixás e com a família de santo foram capazes de transformar suas trajetórias pessoais, modificando suas personalidades e trazendo um estímulo para a melhoria de suas vidas. Concluiu-se, assim, que a religião impactou e impacta diretamente na construção de identidades individuais e coletivas dessas mulheres. Na esfera individual, suas vidas foram afetadas de tal maneira que essas mulheres afirmam que se enxergam como uma pessoa antes e uma pessoa totalmente outra depois do ingresso na religião. Algumas sentem a sua vida mais serena, passaram a ter mais paciência e cautela, outras, no entanto, se apresentam mais encorajadas e rigorosas em situações de tensão. Em comum, as interlocutoras afirmam que a religião é a base para tudo em suas vidas, englobando nessa concepção do todo tanto as suas ações, como as suas expectativas e escolhas. Pela via da coletividade, as identidades são construídas na medida em que essas mulheres se sentem pertencentes a uma rede, onde estão todos e todas conectados em laços de reciprocidade. A vivência no barracão lhes nutre de afeto, segurança e apoio. Sendo assim, a religião atua como sustento de vida e fonte de poder para as mulheres do Ilê Axé Egun.
INTEGRATION OF DATA MINING METHODS DURING INFORMATION AND ANALYTICAL WORK
Authors: Панков А.В. , Багрецов С.А. , Лаута О.С. , Васильев Н.А.
Published: November 2022

В статье представлен концептуальный подход к совершенствованию процессов информационно-аналитической работы при решении задач распознавания состояния частично наблюдаемых объектов управления. Основу предложенного подхода формирует способ агрегирования результатов неравноточного распознавания состояний объектов с использованием нескольких методов идентификации. Приводятся результаты эксперимента по оцениванию качества информационного решения при объединении результатов, полученных с использованием методов машинного обучения.

The article presents a conceptual approach to improving the processes of information and analytical work in solving problems of recognizing the state of partially observed control objects. The basis of the proposed approach is formed by the method of aggregating the results of non-precision recognition of the states of objects using several identification methods. The results of the experiment on evaluating the quality of an information solution by combining the results obtained using machine learning methods are presented.
TOTAL PETROLEUM HYDROCARBONS (TPHS) IN THE SEDIMENT CORES OF TIGRIS, EUPHRATES AND SHATT AL-ARAB RIVERS
Authors: Salem Zainab A. , Mohammed Abbas H. , Al-Saad Hamid T.
Published: November 2022

Due to their widespread distribution in the environment, petroleum hydrocarbons are pollutants that contain a variety of hazardous organic compounds, many of which have the ability to mutate and have cancerous impacts on natural ecosystems To determine the quantities, distribution, and sources of total petroleum hydrocarbon in sediment samples, sediment samples were collected from six locations along the Tigris, Euphrates, and Shatt Al Arab rivers in December 2021. The highest concentration of TPHs was (10.83µ g/g dry weight) in station 6 at Shatt Al-Arab and the lowest was (1.39 µg/g dry weight) in station 3 at Euphrates. These results were compared with previous studies conducted in the same area since 1998. The current study's results indicated that TPHs concentrations in the sediments at the Tigris, Euphrates and Shatt Al-Arab River were within the permitted limits. Therefore, we can come to the concluded that since 1998, these regions of the study have not been significantly contaminated by petroleum hydrocarbons.
PENGEMBANGAN APLIKASI WEB PARIWISATA DANAU TOBA BERBASIS KOMUNITAS (VISIT TOBA)
Authors: Pratama Yohanssen , Sianturi Riyanthi A , Tampubolon Helmuth S , Lumbantoruan Kristopel , Simatupang Hotni M , Tampubolon Indah T , Manullang Yohana C
Published: November 2022

Masalah yang dihadapi oleh beberapa daerah tujuan wisata di Kawasan Danau Toba adalah belum maksimalnya branding dengan menggunakan media digital. Pada penelitian ini kami memiliki tujuan melakukan pembangunan aplikasi community based tourism (CBT) VisitToba untuk mengembangkan potensi pariwisata Kawasan di Danau Toba melalui digitalisasi dengan konsep pemberdayaan komunitas masyarakat, meningkatkan kualitas pariwisata dan ekonomi masyarakat pelaku wisata di kawasan Danau Toba. Aplikasi Visit Toba diharapkan dapat menjadi wadah bagi berkembangnya usaha kecil dan menengah lokal sebagai pendukung pariwisata, di mana para pelaku wisata dapat memanfaatkan fitur yang ada di aplikasi ini untuk dapat saling berkolaborasi membuat suatu paket wisata. Meningkatnya partisipasi masyarakat dalam upaya mengembangkan dan memperkuat pariwisata kawasan Danau Toba adalah hasil yang diharapkan dengan adanya aplikasi ini, sehingga terjalin kemitraan antara pengusaha-pengusaha pariwisata di kawasan Danau Toba dengan adanya paket wisata yang disediakan. Aplikasi yang dibangun menggunakan model Waterfall dan telah lulus tahap pengujian sehingga hasil dalam bentuk website sudah dapat diimplementasikan pada kawasan Danau Toba.
Efectos locales de la expansión cosmológica
Authors:   , Combi Luciano
Published: November 2022

El Universo era extremadamente uniforme en su edad temprana. A partir de pequeñas fluctuaciones en este medio casi homogéneo, inestabilidades gravitacionales dieron lugar a la red cósmica que observamos hoy en día, compuesta de estructuras como cúmulos de galaxias y grandes regiones de baja densidad. La evolución del espacio-tiempo en el Universo está regida por las ecuaciones de Einstein que determinan la curvatura y en consecuencia la dinámica de los sistemas inerciales. Las ecuaciones de Einstein son ecuaciones no-lineales para la métrica, con lo cual, el acople entre regiones locales y el espacio-tiempo global es altamente no trivial. En el Universo, las inhomogeneidades que observamos hoy en día pueden afectar la dinámica global y, viceversa, la expansión global determina las condiciones de contorno de sistemas astrofísicos locales. En esta tesis, investigamos problemas relacionados a la influencia de la expansión global cosmológica en sistemas físicos locales.
Element-selective magnetization states in a Gd23Fe67Co10 alloy, probed by soft X-ray resonant magneto-optical Kerr effect
Authors: Sumi Toshihide , Senoo Tomoaki , Horio Masafumi , El Moussaoui Souliman , Nakamura Eiken , Tanaka Kiyohisa , Tsukamoto Arata , Matsuda Iwao
Published: November 2022

The core-level resonant magneto-optical Kerr effect of a ferrimagnetic metal alloy, Gd23Fe67Co10, was measured at the Fe M-shell and Gd N-shell absorption edges using rotating analyzer ellipsometry. A large Kerr rotation angle of several degrees was detected at room temperature. The signal was found to be strong enough for element-selective magneto-optical experiments to trace various magnetic events, such as all-optical magnetization switching.
Thermal neutron scintillation improvement in Ce:Li6Y(BO3)3 single crystals by thermal treatment
Authors: Yuan Dongsheng , Víllora Encarnación G , Kawaguchi Noriaki , Nakauchi Daisuke , Kato Takumi , Yanagida Takayuki , Shimamura Kiyoshi
Published: November 2022

The development of efficient, low-cost, and stable solid-state materials for portable thermal neutron detection is highly expected in order to substitute the currently used 3He and BF3 tank detectors. A few Li-based glasses and halide compounds have emerged as candidates, however, all of them present critical drawbacks for their practical implementations. Ce:Li6Y(BO3)3 is a priori a very promising oxide candidate that however has been disregarded so far due to its negligibly low light yield, caused by a poor crystalline and optical quality. In this study, we demonstrate that a post-growth thermal treatment is the key parameter to drastically reduce the concentration of intrinsic defects and scattering centers that lead to severe non-radiative recombination of excited electrons. Even though this annealing step also involves the oxidation of activator Ce3+ ions to Ce4+, a drastic enhancement of the light yield by ∼600% is achieved independently of the Ce3+ concentration within the considered range. The obtained light yield of 4650 ph n−1 is already close to that of reference Li-glass (commercial GS20 with 6000 ph n−1). An additional improvement can be envisaged upon further optimization of the Ce3+ concentration and the annealing time, so that Ce:Li6Y(BO3)3 reaches a light yield comparable to the state-of-the-art one for thermal neutron detection.
Pengaruh Current Ratio Terhadap Harga Saham dengan Price to Book Value sebagai Variabel Intervening pada Perusahaan Terklasifikasi SIC-3711 yang Terdaftar di NYSE Periode 2016 - 2020
Authors: Wibowo Agus Adi , Nurhasanah Nunung , Supriyadi Didit
Published: November 2022

Abstract–This study aims to determine the effect of Current Ratio (CR) on Stock Prices with Price to Book Value (PBV) as an intervening variable in standard industry classification companies SIC-3711 listed on the NYSE in the 2016 – 2020 research period. The data used in this study is secondary data obtained from the NYSE website and the company's annual report. The research method uses descriptive verification. The sampling technique in this study uses purposive sampling so that a sample of 7 companies is obtained from a total of 18 companies registered in similar industry classification. Data processing uses Path Analysis using statistical product and services solution (SPSS) software version 25. The results show that Current Ratio (CR) with Price to Book Value (PBV) as an intervening variable has a significant effect on stock prices.

Abstrak–Penelitian ini bertujuan untuk mengetahui pengaruh Current Ratio (CR) terhadap Harga Saham dengan Price to Book Value (PBV) sebagai variabel intervening pada perusahaan klasifikasi industry standar SIC-3711 yang terdaftar di NYSE pada periode penelitian 2016 – 2020. Data yang di gunakan pada penelitian ini merupakan data sekunder yang diperoleh dari laman NYSE serta laporan tahunan perusahaan. Metode penelitian menggunakan deskriptif verifikatif. Teknik sample pada penelitian ini menggunakan purposive sampling sehingga di peroleh sampel sejumlah 7 perusahaan dari total 18 perusahaan yang terdaftar pada klasifikasi industry sejenis sejenis. Pengolahan data menggunakan Path Analysis dengan menggunakan aplikasi software statistical product and services solution (SPSS) Versi 25. Hasil penelitian menunujukkan bahwa Current Ratio (CR) dengan Price to Book Value (PBV) sebagai variabel intervening berpengaruh signifikan terhadap Harga Saham
Metode Visual, Auditorial dan Kinestetik dalam Meningkatkan Mutu Belajar Anak Suku Laut Kawal Pantai
Authors: Layla Muslena , Zola Auva , Fitri Diana Setya , Puspita Eryn , Three Ermit , Ridwan Muhammad , Arhafizh Muhammad , Nuraida Nuraida , Octaviani Susanti , Lisnawati Lisnawati , Safina Safina , Mahindra Yusril
Published: November 2022

Kegiatan pengabdian ini bertujuan untuk menerapkan metode visual, auditori dan kinestetik dalam proses pembelajaran di Rumah Pintar. Penerapan metode ini dimaksudkan untuk memberikan warna baru dalam pembelajaran di Rumah Pintar. Kegiatan ini dilakukan pada bulan September-Oktober 2021 saat kegiatan Kuliah Kerja Nyata (KKN) STAIN Sultan Abdurrahnan dilaksanakan. Kegiatan ini menggunakan pendekatan Participatory Action Research (PAR). Anak-anak di rumah Pintar diberikan materi pelajaran Bahasa Inggris menggunakan ketiga metode yaitu visual, auditori dan kinestetik. Setelah kegiatan ini dilaksanakan, anak-anak di Rumah Pintar lebih mudah menyerap dan memahami materi yang diajarkan. Antusiasme dan semangat anak-anak dalam belajar juga semakin meningkat dengan adanya metode belajar visual, auditori dan kinestetik.
A SUPERAÇÃO DA REIFICAÇÃO NA EDUCAÇÃO E FORMAÇÃO HUMANA PELA DIALÉTICA
Authors: Dantas Diego
Published: November 2022

: Este ensaio pretende, através de abordagem dialética, pesquisa teórica e exploratória, confluir as ideias de Gramsci e Lukács, na perspectiva que tinham da ortodoxia do método dialético, cada um a seu modo (historicidade e totalidade), e que é um método ímpar para teoria e uma prática educativa no sentido mais lato do termo, isto é, de formação humana. Como esta dialética em uma ontologia da educação é central para o pensamento de Saviani, não à toa estamos utilizando-o como mediação para este ensaio. E, também a formação como salto ontológico e dialético da ideologia a partir a reprodução econômica que também foi um ponto de confluência entre os dos artífices do pensamento marxista. Pois, para os dois, e isto fica claro na Ontologia e nos Cadernos, a ideologia é o veículo de que os homens se utilizam para dar respostas aos conflitos da experiência. Portanto, a educação precisa ser uma intervenção ideológica para demover crenças do senso comum e transmutá-las para uma consciência emancipada, porém, um problema que não passa ao largo deste ensaio, é superar a imersão de uma consciência reificada, reproduzida pela estrutura capitalista. Enfrentar este debate é vital para os intelectuais da América Latina no trato da educação e da formação da consciência da classe trabalhadora, uma vez que é imanente à realidade da mesma. A metodologia adotada para o problema em questão é seguir com referencial teórico em Lukács, Gramsci e Marx, buscando partir da reprodução econômica, e do processo de reificação na estrutura capitalista para avaliar os desdobramentos no trabalho, na sociedade, no Estado, nas ciências, filosofia e arte, e como tal panorama serve de óbice à elevação e formação da consciência da classe trabalhadora.
GRAMSCI EM PORTUGAL: UM AUTOR AINDA A DESCOBRIR
Authors: Neves Rita Ciotta
Published: November 2022

O artigo propõe uma reflexão acerca do desinteresse pelos estudos sobre Gramsci em Portugal. A partir de alguns apontamentos a respeito do desenvolvimento sócio-histórico da sociedade portuguesa, percebemos que o desinteresse em Gramsci manifesta os desdobramentos de contradições inscritas na própria formação desta sociedade, a saber: certa passividade com relação às questões políticas e sociais do país; a condução política e ideológica do PCP de alinhamento à URSS que, além de ter afastado os estudos sobre Gramsci do escopo de seus interesses, contribuiu para a distensão do fenômeno atual de russofobia e anticomunismo; e o caráter historicamente conservador das universidades portuguesas. Concluímos o artigo indicando que há boas perspectivas para o avanço dos estudos sobre Gramsci em Portugal, salientando que para tanto, é preciso superar o estado de coisas apontado em nossas argumentações
ADAPTATION OF HIGHER EDUCATION INSTITUTIONS TO THE PROCESS OF PROVIDING EDUCATIONAL SERVICES IN THE CONDITIONS OF DIGITAL TRANSFORMATION
Authors: GARAFONOVA Olga , LAZARENKO Yuliiya , DYKHNYCH Lydmila , POLISHCHUK Lydmila
Published: November 2022

Today, the spread and dominance of the digital economy prioritizes such phenomena as the liberalization of the vast majority of activity areas, individualization of preferences as opposed to standardization, expanding the boundaries of space and time due to the transformation of production into service activities. In the field of new requirements for accreditation of scientific and educational programs, the market of educational services is forcing to acquire qualities that can improve the quality of educational services. Universities face new requirements such as compliance with the licensing conditions that universities must comply with in order to pass the accreditation process. That is why there is a problem of forming an adequate demand for educational services from the citizens of Ukraine, which can be provided only by bringing them promising, truthful information about the expectations of employers and opportunities for providers of educational services. Adapting higher education institutions (HEIs) to changing internal and external conditions is a necessary measure today. The purpose of the article is to substantiate the conditions and trends of adapting free economic zones to the new conditions of providing educational services. Due to the new requirements for the accreditation of HEIs and specialties, we are waiting for new licensing conditions for teachers. Because adhering to the new licensing conditions it is possible to develop in the modern conditions of digital transformation of society. When determining the achievements in the professional activity of a scientific-pedagogical (scientific) worker, achievements at previous jobs may be credited, the five-year term may be extended for a break during work for objective reasons (social leave, conscription / mobilization for military service or military contract service, long-term illness, etc.), and that is all. We hope that the new perspectives for free economic development and the development of their teaching staff will be more adaptive and variable.
Key words: economic efficiency, higher education institutions, educational services, quality of education.
Liquid Foaming Agent for Liquid Loading Reduction in Gas Producing Wells
Authors:   Master of Gas Engineering, Universidad de Oriente-Núcleo de Monagas, Maturín, 6201, Venezuela, Oca José Daniel , Castillo-Campos Luis ,   Petroleum Engineering Department, Universidad de Oriente-Núcleo de Monagas, Maturín, 6201, Venezuela, Vega Rubén ,   Petroleum Engineering Department, Universidad de Oriente-Núcleo de Monagas, Maturín, 6201, Venezuela
Published: November 2022

The main objective of this research was to develop a liquid foaming agent for optimizing gas production in wells belonging to the Santa Rosa field in Área Mayor de Anaco, Venezuela. In this research, three liquid foaming agent formulations were developed with an anionic and amphoteric surfactants mixture, performing tests to evaluate foaming and lifetime on samples with different produced water/hydrocarbon condensate ratios. A liquid drag test was also carried out, explaining the liquid recovery performance after applying the developed formulations at different dosages and finally evaluated products results were compared with a commercial one. Formulation 1 obtained a higher liquid recovery compared to the other formulations, in addition, recovered liquid amount in dynamic drag tests decreased as the condensates composition increased in four samples evaluated. Formulation 1 and commercial product used as a reference did not have statistically significant differences.
Arabic text watermarking tuned for medical e-record semi-authentication
Authors:   Computer Engineering Department, Umm Al-Qura University, Makkah, Saudi Arabia, Gutub Adnan , Almehmadi Esraa
Published: November 2022

This study focuses on Arabic text watermarking semi-verification utilizing recent counting-based secret-sharing to partially validate the ownership and correctness for all sensitive medical e-records. The benefit of this approach is its semi-trust of e-records, as needed services provided, even if complete text medical report is a bit delayed for full verification. The Proposed work is presents two approaches of text-watermarking which are Seed Shares approach and WM Shares approach. The capacity results of our approaches is achieved without effect of secret bits hidden. The security is achieved via using XOR operation and CBSS technique. The comparisons result shows that the Accuracy percentage of the seed shares approach is much better than the WM in terms of tampering attack. The exploration tested its proposed strategy on standard Arabic benchmark of 42 Nawawi Hadiths which provided promising remarks, which can also be useful for Urdu and Farsi texting.
Optimal Sizing of a Centralized Hybrid Photovoltaic System for Efficient Operation of Street Lights
Authors:   Department of Electrical Engineering and Technology, Government College University Faisalabad, Faisalabad 38000, Pakistan, Tamoor Muhammad , Bhatti Abdul Rauf ,   Department of Electrical Engineering and Technology, Government College University Faisalabad, Faisalabad 38000, Pakistan, Butt Arslan Dawood ,   Department of Electrical Engineering and Technology, Government College University Faisalabad, Faisalabad 38000, Pakistan, Miran Sajjad ,   Department of Mechanical Engineering, University of Gujrat, Gujrat 50700, Pakistan, Kiren Tayybah ,   Department of Computer Science (RCET), University of Engineering and Technology, Lahore, 54890, Pakistan, Farhan Muhammad ,   Department of Electrical Engineering and Technology, Government College University Faisalabad, Faisalabad 38000, Pakistan, Raza Faakhar ,   Department of Sociology, Government College University Faisalabad, 38000, Pakistan, ZakaUllah Paris ,   Department of Sociology, Government College University Faisalabad, 38000, Pakistan
Published: November 2022

The photovoltaic energy generation system is one of the most promising technology to meet our future electricity demand as well as mitigate climate change. This study aims to design, simulate and evaluate the performance of hybrid photovoltaic (PV) system using PVsyst software to supply electricity for energy efficient streetlights in educational institute. Meteonorm database of daily and monthly irradiation, temperatures, precipitation and sunlight hours are utilized while performing the analysis. The photovoltaic system consists of 56 bifacial-polycrystalline 360-watt PV modules having 17.9% efficiency. The photovoltaic modules were installed at 0° azimuth angle and 15° tilt angle. Two hybrid inverters with rated capacity of 10 kW are used. The energy storage system consists of 16 batteries (2 in series x 8 in parallel) with a nominal capacity of 1600 ampere-hours and discharging minimum SOC is 20 %. A total of 100 streetlight poles with 8 working-hours/day are installed to cover both sides of the road, with monthly energy consumption of 672 kilowatt-hours. The average annual ambient temperature is 23.66℃, and the annual GH irradiation is 1693 kilowatt-hour/m2. The annual production of the hybrid PV system is 25.96 MWh/year, the specific energy production of the system is 1288 kWh/kWp/year with 70.38% performance ratio. By means of proposed photovoltaic system for energy efficient street lightning structure, 157.9t CO2 is reduced. The project can save 0.004737 million tonnes of CO2 emissions over its lifetime of 30 years. The proposed system is a viable solution for public lighting with the right selection of system components.