bluuebunny/crossref_metadata_2025 huggingface dataset:
PSUN187 Validation of a multi-frequency bioelectrical impedance analysis device for the assessment of body composition in older adults with type 2 diabetes
Authors: Buch Assaf , Eldor Roy , Greenman Yona , Izkhakov Elena , Rouach Vanessa
Published: November 2022

Background

Aging and type 2 diabetes (T2DM) are associated with an increased risk of developing sarcopenia which is associated with poor outcomes and may necessitate specific treatment. Diagnosis of sarcopenia often requires the referral of patients to dual-energy X-ray absorptiometry (DXA) in specialized settings. Another available method for assessing body composition is direct segmental multi-frequency bioelectrical impedance analysis (DSMF-BIA). In this study, we examine the accuracy of a DSMF-BIA (InBody 770) for assessing body composition in older adults with T2DM when compared to DXA.

Methods

84 older adults (49 women, age 71 ± 5 years. Body mass index 30 ± 5.6 kg /m2) with T2DM who were recruited for the CEV-65 study and had both DSMF-BIA and DXA assessments at baseline were included in the analysis. The main analysis included Bland-Altman plots and Intra Class Correlation Coefficients (ICC). Sub-analyses were performed according to gender and following 10 weeks of intervention (diet, circuit resistance training, and Empagliflozin).

Results

The leg lean mass results according to DSMF-BIA and DXA were 14.76 ± 3.62 kg and 15.19 ± 3.52 kg respectively, however, did not differ between devices according to Bland-Altman analyses (p=0.353). Assessment of appendicular skeletal mass index did not differ between DSMF-BIA and DXA (7.43 vs. 7.47 kg/m2; p=0.84; ICC=0.965, p<0.0001; bias of -0.068, p =0.595). The accuracy of DSMF-BIA was limited when estimating fat mass indices reflected by significant biases according to Bland-Altman analyses.

In a sample of older adults with T2DM the degree of agreement between DSMF-BIA and DXA, was high, supporting the use of DSMF-BIA for the diagnosis of low muscle mass. Better accuracy was observed when comparing parameters of lean mass versus parameters of fat mass. Gender as well as three common treatment modalities for T2DM did not modify the accuracy of the DSMF-BIA when compared to DXA.

Presentation: Sunday, June 12, 2022 12:30 p.m. - 2:30 p.m.
Incidentalomas in the head & neck
Authors: McQueen Andrew , Al-Zuhir Naail , Ali Tamir
Published: November 2022

Incidental findings (IFs) in the head & neck are a frequent challenge to the reporting radiologist. A combination of complex anatomy, widely varied imaging techniques and the high prevalence of benign pathology, makes safe and appropriate management of head & neck IFs problematic. The non-head & neck radiologist is unlikely to have prior personal experience of the relevant specialties or current involvement with the pertinent multidisciplinary teams, creating unfamiliarity with both the clinical aspects of head & neck disease and the value of examination techniques. This triumvirate of complex anatomy, pathology and imaging creates the perfect environment for excessive investigation and overdiagnosis. In this article, the most frequently encountered and clinically relevant head & neck IFs are summarised. To reflect daily clinical practice, we will firstly consider anatomic abnormalities identified on cross-sectional imaging and ultrasound, followed by a review of PET-CT incidental findings.
Multimodal locoregional procedures for cancer pain management: a literature review
Authors: Iezzi Roberto , Kovács György , Dimov Vladimir , Contegiacomo Andrea , Posa Alessandro , Efthymiou Evgenia , Lancellotta Valentina , Rodolfino Elena , Punzi Ernesto , Trajkovski Zoran B , Valentini Vincenzo , Manfredi Riccardo , Filippiadis Dimitrios
Published: November 2022

Pain is the most common and fearsome symptom in cancer patients, particularly in the advanced stage of disease. In cancer pain management, the first option is represented by analgesic drugs, whereas surgery is rarely used. Prior to considering surgical intervention, less invasive locoregional procedures are available from the wide pain management arsenal. In this review article, comprehensive information about the most commonly used locoregional options available for treating cancer pain focusing on interventional radiology (neurolysis, augmentation techniques, and embolization) and interventional radiotherapy were provided, also highlighting the potential ways to increase the effectiveness of treatments.
Structure and thermodynamics of a UGG motif interacting with Ba2+and other metal ions: accommodating changes in the RNA structure and the presence of a G(syn)–G(syn) pair
Authors: Kiliszek Agnieszka , Pluta Martyna , Bejger Magdalena , Rypniewski Wojciech
Published: November 2022

The self-complementary triplet 5′UGG3′/5′UGG3′ is a particular structural motif containing a noncanonical G–G pair and two U·G wobble pairs. It constitutes a specific structural and electrostatic environment attracting metal ions, particularly Ba2+ions. Crystallographic research has shown that two Ba2+cations are located in the major groove of the helix and interact directly with the UGG triplet. A comparison with the unliganded structure has revealed global changes in the RNA structure in the presence of metal ions, whereas thermodynamic measurements have shown increased stability. Moreover, in the structure with Ba2+, an unusual noncanonical G(syn)-G(syn) pair is observed instead of the common G(anti)-G(syn). We further elucidated the metal binding properties of the UGG/UGG triplet by performing crystallographic and thermodynamic studies using DSC and UV melting with other metal ions. The results explain the preferences of the UGG sequence for Ba2+cations and point to possible applications of this metal-binding propensity.
The philanthropy's crucial role in alleviating stunting in Indonesia through research funding: A policy brief
Authors: Morasa Jenny , Nurkolis Fahrul , Narasiang Bezaliel R. , Visnu Jodi , Mayulu Nelly , Taslim Nurpudji Astuti , Gunawan William Ben , Handoko Matthew Nathaniel , Hardinsyah Hardinsyah
Published: November 2022

Background: Developing countries need funding for researchers to maximize the evidence base, especially in stunting research. This short policy is expected to provide opportunities for Indonesia to receive more research funding to stunt philanthropists.

Policy and implications: Multi-sector cooperation is arguably the leading player in acceleration programs to reduce growth delays. The Stunted Reduction Acceleration Program, complemented by higher research and development expenditures (RDEs) and open policies to support philanthropic activities in Indonesia, will help improve the efficiency of stunted stunt reduction through adequate funding and investment. As evidenced by Singapore and Thailand, the increase in government budgets focused on research and development (R&D) and supportive environments, as shown by Global Philanthropy Environment Index (GPEI), prove that evidence-based and practical researches can lead to the reduction of estimated prevalence of stunting rather than innovation-stage research.

Recommendations: Attention needs to be directed in proposing major changes in law and policy which regulate the allocation of research-development expenditure, which will initiate the creation of a supportive environment for philanthropy acts regarding stunting. The challenges associated with these issues are: (1) Stunted research and innovation are still left behind, (2) The availability of data and the lack of transparency, (3) Subpar performance in relation to philanthropists, (4) Inconsistent legal definitions and a lack of industry-specific guidelines, (5) Inadequate law enforcement, (6) Local leaders must engage in evidence-based advocacy, (7) Philanthropists have limited opportunities to learn.
Ex vivo comparative investigation of suprachiasmatic nucleus excitotoxic resiliency
Authors: Acharyya Debalina , Cooper Joanna , Prosser Rebecca
Published: November 2022

Background: Glutamate signaling in the brain is regulated by release, reuptake, and receptor responsiveness. In diseased conditions, glutamate signaling can exceed normal regulatory processes, giving rise to a condition called excitotoxicity. Although regional differences in the excitotoxic effects of glutamate in the brain have been reported, the extent and characteristics of these potential differences are not clear.  Here we compared the excitotoxic resiliency of the suprachiasmatic nucleus (SCN), anterior hypothalamus (AH) and cortex. 

Methods: We treated acute brain slices containing either the SCN and AH or the cortex from adult male mice at different times across the diurnal cycle with varying concentrations of N-methyl-D-aspartate (NMDA), NMDA+ α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) or control medium. The extent of cell damage was assessed using propidium iodide (PI), a cell death marker.

Results: The results indicate that all three brain regions exhibited increasing cell damage/death when treated with increasing concentrations of NMDA. However, higher concentrations of NMDA were needed to significantly increase cell damage in the SCN compared to the cortex and AH.  All three brain regions also exhibited greater cell death/damage when treated in the nighttime compared to the daytime, although the SCN exhibited increased cell death during a more restricted time interval compared to the AH and cortex. 

Conclusions: Together, these data confirm previous studies showing excitotoxic resiliency in the SCN, while extending them in two ways.  First, we demonstrate a dose-dependency in excitotoxic susceptibility that differentiates the SCN from the surrounding AH and the cortex using a brain slice preparation. Second, we demonstrate a diurnal rhythm in excitotoxic susceptibility with a broadly similar phase across all three brain regions. These data increase our understanding of the extent and nature of the SCN excitotoxic resiliency, which will inform future studies on the cellular mechanisms underlying this phenomenon.
Using Digital Marketing for Small and Medium Enterprises (SMEs) in Bumdes Remboko Sumberrejo Village Sleman Regency
Authors: Maulana Zain , Chanif Hidayat Muhammad , Agustina Imaniar
Published: November 2022

Background: This community service aims to assist and empower the small and medium enterprises (SMEs) of the UMKM Bumdes Remboko to have highly digital marketing in Yogyakarta. Also, it focuses on maximizing the use of the internet specifically social media and the marketplace for branding, promoting, and selling its products. This study emphasizes that SMEs need to embrace digital technology in performing their business.
Contribution: Empowerment is important because it upgrades the small and medium enterprises to face competition with others.
Method: Several activities including creating a social media account, photography training, webinar, and registering of Go-Food were used to increase the SMEs' abilities in using the internet.
Results: The results showed that these activities help SME partners of Bumdes Remboko use digital marketing through social media and the marketplace.
Conclusion: In conclusion, it is expected that small and medium enterprises increase their business by using digital methods
Improving the Quality of Learning Content for Teachers of SMK Windusari Magelang
Authors: Hendradi Purwono , Yudatama Uky , Nuryanto Nuryanto , Ratna Arumi Endah , Nugroho Setiya
Published: November 2022

Background:  The need to increase the mastery of Information and Computer Technology (ICT) in teaching and learning activities is essential and urgent, especially during the COVID-19 pandemic. The PowerPoint application is a popular application for creating learning content, but most teachers are only at the level of "powerpointers". SMK Negeri Windusari, as a vocational high school, requires an increase in the level of its educators, namely those who can increase learning outcomes, one of which is by developing multimedia content based on PowerPoint. This training was in collaboration with UNIMMA Informatics Engineering. It was attended by twenty-four teachers starting with a pre-test and ending with a post-test to measure the level of success.
Contribution: Improving the quality of content to support learning outcomes.
Method:  The training on the use of ICT for learning begins with observation through a pre-test and ends with a presentation of the training results, and then measures progress using a post-test.
Results:  The results of the training showed that most of the  participants showed improvement.

Conclusion:  This training is expected to be sustainable as a form of support for improving the quality of learning content
Determining the Priority of Business Development Strategy for Kunir Jalak Business Unit, SMK Muhammadiyah 1 Moyudan, Sleman
Authors: Budijati Siti Mahsanah , Astuti Fatma Hermining , Jatiningrum Wandhansari Sekar , Ichwanudin Aziz
Published: November 2022

Background: Kunir Jalak business unit is part of UPJ Surya Boga belonging to the Catering Department at SMK Muhammadiyah 1 Moyudan, Sleman. This unit produces a powder drink made from turmeric, ginger, and temulawak. This drink is intended to maintain immunity, considering the covid 19 pandemic. The Kunir Jalak business unit is relatively new, so it still needs assistance to develop its business. This community service activity aims to assist in determining business development strategies so that the Kunir Jalak business unit can be more developed.

Contribution: The impact of community service activities is shown by increasing partners’ empowerment in identifying strengths, weaknesses, opportunities, and threats (SWOT) for the Kunir Jalak business unit and determining the alternative business development strategy, which has never been done before.       

Method: The method used is Focus Group Discussion (FGD) to determine strengths, weaknesses, opportunities, and threats (SWOT) and determine business development strategies. Furthermore, the Analytical Hierarchy Process (AHP) approach determines strategic priorities.

Results: AHP analysis shows three business development strategies with the highest priority, namely: Weakness-Treats-1 (WT-1), Strength-Treats-1 (ST-1), and Weakness-Opportunity-2 (WO-2).

Conclusion: Following the objectives of the community service program, it means that the priority of business development strategies can be determined, which can be used as guidelines for developing the business unit of Kunir Jalak.
Antibiotics for the secondary prevention of coronary heart disease
Authors: Mansoor Mohamed , Hamer Oliver , Walker Emily , Hill James
Published: November 2022

An estimated 200 million people live with coronary heart disease, which remains one of the leading causes of mortality and morbidity worldwide. Those living with coronary heart disease are at an increased risk of cardiovascular events, such as stroke, myocardial infarction and cardiovascular death. The pathophysiology of coronary heart disease revolves around inflammation, which leads to plaque build up. Antibiotics are known to hold anti-inflammatory and anti-oxidative properties. It has been theorised that reductions in inflammation could prevent cardiovascular events, which may reduce symptoms, risk of death and hospital admission rates in patients with coronary heart disease. This article critically appraises a systematic review that assessed the risks associated with using antibiotics as secondary prevention for coronary heart disease.
How to nurture workplace wellness
Authors: Wassall Claire
Published: November 2022

Claire Wassall offers insight on ensuring excellent mental and physical health within dentistry.
Water flossing – the perfect companion to orthodontics
Authors: Hudson Susan
Published: November 2022

Susan Hudson discusses the benefits of adding water flossing to your dental routine.
How dentists continue to make appointments covid safe
Authors: Younger James
Published: November 2022

James Younger discusses the collective effort in dentistry to continue covid safety.
Development of Smart City Policies in First-tier Cities in China
Authors:   Department of Urban and Regional Planning, Faculty of Architecture, Chulalongkorn University, Thailand, Yin Mingqing , Anantsuksomsri Sutee ,   Department of Urban and Regional Planning, Faculty of Architecture, Chulalongkorn University, Thailand,   Regional, Urban, and Built Environmental Analytics, Faculty of Architecture, Chulalongkorn University, Thailand
Published: November 2022

ABSTRACT To explore the policy tools to study the smart city policies in Chinese first-tier cities, which can help to promote the direction of smart city management. This research adopts a quantitative textual analysis method to collect relevant policies of Chinese first-tier cities from 2010 to 2021, and constructs a pilot analysis of smart city policies from supply-based, demand-based, and environmental perspectives by using Nvivo literature coding software. The results of the research show that local governments should strengthen the integration and sharing of information resources, improve the management of smart city industry chain, optimize the management mode, eliminate digital barriers, and realize the transformation from traditional management to smart management on the basis of strengthening information security measures. Keywords: Smart city policy, Quantitative text analysis, Urban strategies, Policy analysis tools
Sex discrimination based on morphological traits in Mystus mysticetus Roberts, 1992
Authors:   Department of Biology, School of Education, Can Tho University, Can Tho 900000, Vietnam, Phan Thu Quynh , Tran Anh Ngoc ,   Department of Biology, School of Education, Can Tho University, Can Tho 900000, Vietnam, Thao Vo Lam Thi ,   Department of Biology, School of Education, Can Tho University, Can Tho 900000, Vietnam, Dinh Quang Minh ,   Department of Biology, School of Education, Can Tho University, Can Tho 900000, Vietnam
Published: November 2022

This study supplemented the way of sex determination of fish based on the regression relationship of some morphological indicators of Mystus mysticetus. A total of 425 fish specimens were collected by trawl nets at Cai Rang - Can Tho and Long Phu - Soc Trang from January to July 2022. After collection, the fish were transferred to the laboratory to determine their total length (TL), standard length (SL), eye diameter (ED), eye distance (DE), body height (BD), head length (HL), and mouth width (MD) before anatomy for sex determination based on gonads. The regression analysis results of TL-SL, TL-ED, TL-DE, TL-BD, TL-HL, and TL-MD showed that SL, DE, and MD could be used to determine the sex of this fish species because SL and DE were dominant in growth in males, and MD was prevalent in females. In addition, SL could be used to determine the sampling time and HL to determine the distribution environment.
Effect of fluoxetine on cyclic adenosine monophosphate response to follicle-stimulating hormone in HEK cells
Authors:   Department of Primary Education and Preschool, Quy Nhon University, Binh Dinh 550000, Vietnam, Nguyen Thi Tho , Nguyen Thi Mong Diep ,   Faculty of Natural Sciences, Quy Nhon University, Binh Dinh 550000, Vietnam
Published: November 2022

Fluoxetine is an antidepressant that acts as a selective serotonin reuptake inhibitor. Fluoxetine has exhibited different mechanisms of action on many different cell lines. In this study, the effect of fluoxetine on cAMP production in human embryonic kidney (HEK) cells under the stimulation of bovine follicle-stimulating hormone were examined. HEK cells were incubated for 60 minutes with fluoxetine at different concentrations (0, 6.25, 12.5, 25 and 50 μM), and then cAMP accumulation, ATP level, and AMPK phosphorylation and cell viability were tested. Our results showed that fluoxetine at 25 and 50 μM attenuated cAMP levels in cells after bFSH stimulation. The depletion of cAMP at this concentration is accompanied by a decrease in ATP energy and an increased capacity to phosphorylate AMPK. As such, this study showed that fluoxetine induces a reduction in cAMP accumulation and that it is associated with the AMPK pathway in HEK cells
Pseudomonas aeruginosa from pet Chinese stripe-necked turtles (Ocadia sinensis) demonstrating antimicrobial and heavy metal resistance
Authors:   Laboratory of Aquatic Animal Medicine, Veterinary Medical Center and College of Veterinary Medicine, Chungbuk National University, Cheongju 28644, Republic of Korea (South Korea), Wickramanayake M.V.K.S. , De Silva L.A.D.S. ,   Laboratory of Aquatic Animal Medicine, Veterinary Medical Center and College of Veterinary Medicine, Chungbuk National University, Cheongju 28644, Republic of Korea (South Korea), Heo Gang-Joon ,   Laboratory of Aquatic Animal Medicine, Veterinary Medical Center and College of Veterinary Medicine, Chungbuk National University, Cheongju 28644, Republic of Korea (South Korea)
Published: November 2022

Leading nosocomial pathogen Pseudomonas aeruginosa has increasingly been reported to be an opportunistic pathogen. In this study, a total of twenty P. aeruginosa isolates were isolated from 40 pet Chinese stripe-necked turtles and examined for their antimicrobial and heavy metal resistance properties. All isolates were multidrug resistance by scoring multiple antimicrobial resistance indices ≥0.2. In the disc distribution test, 100% resistance to ampicillin and oxacillin were detected. In addition to that, 14 (70%) isolate demonstrated amoxicillin resistance. Imipenem, fosfomycin, gentamycin, tobramycin and piperacillin resistance were detected in 40%, 15%, 20%, 10% and 5% of the isolates, respectively. The ESBLs gene that predominated in this study was blaSHV (55%), followed by blaTEM (50%), blaCTX (10%) and blaOXA (5%). The most frequent aminoglycoside resistance gene in this study was aac(6´)-Ib (40%). Class1 integron integrase gene intI1 and class 1 integron gene cassette gene aadA1 were detected in 45% and 35% of the isolates, respectively. All P. aeruginosa isolates demonstrated Cu and Cd resistance. CzcA and CopA genes were detected in 65% and 30% of the isolates, respectively. These findings reveal the presence of pet turtle-born P. aeruginosa can be a potential risk to public health and cannot be excluded as a non-nosocomial source of infections.
Validating the use of 3D biplanar radiography versus CT when measuring femoral anteversion after total hip arthroplasty
Authors: Anderson Christopher G. , Brilliant Zachary R. , Jang Seong J. , Sokrab Ruba , Mayman David J. , Vigdorchik Jonathan M. , Sculco Peter K. , Jerabek Seth A.
Published: November 2022

Aims

Although CT is considered the benchmark to measure femoral version, 3D biplanar radiography (hipEOS) has recently emerged as a possible alternative with reduced exposure to ionizing radiation and shorter examination time. The aim of our study was to evaluate femoral stem version in postoperative total hip arthroplasty (THA) patients and compare the accuracy of hipEOS to CT. We hypothesize that there will be no significant difference in calculated femoral stem version measurements between the two imaging methods.

Methods

In this study, 45 patients who underwent THA between February 2016 and February 2020 and had both a postoperative CT and EOS scan were included for evaluation. A fellowship-trained musculoskeletal radiologist and radiological technician measured femoral version for CT and 3D EOS, respectively. Comparison of values for each imaging modality were assessed for statistical significance.

Results

Comparison of the mean postoperative femoral stem version measurements between CT and 3D hipEOS showed no significant difference (p = 0.862). In addition, the two version measurements were strongly correlated ( r = 0.95; p < 0.001), and the mean paired difference in postoperative femoral version for CT scan and 3D biplanar radiography was -0.09° (95% confidence interval -1.09 to 0.91). Only three stem measurements (6.7%) were considered outliers with a > 5° difference.

Conclusion

Our study supports the use of low-dose biplanar radiography for the postoperative assessment of femoral stem version after THA, demonstrating high correlation with CT. We found no significant difference for postoperative femoral version when comparing CT to 3D EOS. We believe 3D EOS is a reliable option to measure postoperative femoral version given its advantages of lower radiation dosage and shorter examination time. Cite this article: Bone Joint J 2022;104-B(11):1196–1201.
Spinal versus general anaesthesia in contemporary primary total knee arthroplasties
Authors: Owen Aaron R. , Amundson Adam W. , Larson Dirk R. , Duncan Christopher M. , Smith Hugh M. , Johnson Rebecca L. , Taunton Michael J. , Pagnano Mark W. , Berry Daniel J. , Abdel Matthew P.
Published: November 2022

Aims

Spinal anaesthesia has seen increased use in contemporary primary total knee arthroplasties (TKAs). However, controversy exists about the benefits of spinal in comparison to general anaesthesia in primary TKAs. This study aimed to investigate the pain control, length of stay (LOS), and complications associated with spinal versus general anaesthesia in primary TKAs from a single, high-volume academic centre.

Methods

We retrospectively identified 17,690 primary TKAs (13,297 patients) from 2001 to 2016 using our institutional total joint registry, where 52% had general anaesthesia and 48% had spinal anaesthesia. Baseline characteristics were similar between cohorts with a mean age of 68 years (SD 10), 58% female (n = 7,669), and mean BMI of 32 kg/m2 (SD 7). Pain was evaluated using oral morphine equivalents (OMEs) and numerical pain rating scale (NPRS) data. Complications including 30- and 90-day readmissions were studied. Data were analyzed using an inverse probability of treatment weighted model based on propensity score that included many patient and surgical factors. Mean follow-up was seven years (2 to 18).

Results

Patients treated with spinal anaesthesia required fewer postoperative OMEs (p < 0.001) and had lower NPRS scores (p < 0.001). Spinal anaesthesia also had fewer cases of altered mental status (AMS; odds ratio (OR) 1.3; p = 0.044), as well as 30-day (OR 1.4; p < 0.001) and 90-day readmissions (OR 1.5; p < 0.001). General anaesthesia was associated with increased risk of any revision (OR 1.2; p = 0.021) and any reoperation (1.3; p < 0.001).

Conclusion

In the largest single institutional report to date, we found that spinal anaesthesia was associated with significantly lower OME use, lower risk of AMS, and lower overall 30- and 90-day readmissions following primary TKAs. Additionally, spinal anaesthesia was associated with reduced risk of any revision and any reoperation after accounting for numerous patient and operative factors. When possible and safe, spinal anaesthesia should be considered in primary TKAs. Cite this article: Bone Joint J 2022;104-B(11):1209–1214.
Conversion of Oil Shale To Liquid Hydrocarbons as A New Energy Resources Using Iron (Fe)-Pillared Clay (Kaolinite) Catalyst
Authors: Dewanto Ordas , Ferucha Istifani , Darsono Darsono , Rizky Sri
Published: November 2022

In the context of new energy exploration, oil shale is currently a source of energy that is being developed so that it can be used as an alternative energy in the future. Based on this background, it is important to research the conversion method of oil shale to liquid hydrocarbons. The method used is using clay (kaolinite) catalyst and  iron (Fe)-pillared clay (kaolinite) catalyst. Clay catalyst products are capable of making organic mature faster and even requiring a lower temperature for the changes (through thermal cracking of non-volatile organic material). The addition of Fe metal in the clay catalyst product to oil shale, causing the surface area of the natural clays were significantly increased, then the volume of micro pore were also increased, it causes the organic material to mature faster and the temperature required for the change is less than the shale material without Fe. The catalyst method by the pillarization technique able to increase the surface area and pore volume, thus accelerating the reaction and changing the reaction rate to be greater. It is observed that clay catalyst products can serve as catalysts for accelerating organic maturation reactions. if compared between the clay material  of OD1-Ast1 (50% clay-50% organic), OD1-Ast2 (33% clay-67% organic), and the OD1-Ast3 shale material (67% clay - 33% organic),then OD1-Ast3 has a faster reaction rate. Comparison of clay material is smaller than organic, then the properties of the catalyst product to accelerate the reaction are reduced, such as the OD1-Ast2 shale material has a slow reaction rate compared to the OD1-Ast3 shale material. The addition of Fe metal in the clay catalyst product to the OD1-Ast2 shale material, resulting in OD1-Ast2-Fe shale material (75% OD1-Ast2 and 25% Fe) having a faster reaction rate than before the addition of Fe metal.The design of heavy (%) clay (kaolinite) and Fe pilaration on oil shale were greatly influence the change of TOC values when heated,then affecting maturation and Tmax. The temperature of maturation and Tmax as the main parameters of conversion of oil shale to liquid hydrocarbon. This method supports the development of science and technology in the field of exploitation and processing of natural resources.
Achieving and sustaining improvements in gallstone improvement collaboratives
Authors: Bamber JR , Beckingham IJ , Stephens TJ , MacSween S , Tomlinson RP
Published: November 2022

How can we work collaboratively to make permanent and lasting improvements to gallstone care?
Green innovation doesn't always have to be high tech (just high priority)
Authors: Dobbs Tom , Scott Kathy
Published: November 2022

Healthcare sustainability is one of the critical issues of our time. Prior to the COVID-19 pandemic an article in The Lancet stated that the global climate crisis was the biggest challenge facing global healthcare.
Breakdown of the single-collision condition for soft x-ray high harmonic generation in noble gases
Authors: Chevreuil Pierre-Alexis , Brunner Fabian , Thumm Uwe , Keller Ursula , Gallmann Lukas
Published: November 2022

High harmonic generation (HHG) in atomic gases is generally assumed to
originate from photoelectrons that are not perturbed by neighboring
particles. In this paper, we study theoretically and experimentally
the regime where this approximation breaks down. At high laser
intensities, we experimentally find that producing soft x-rays beyond
this single-collision condition leads to a strong reduction of the
coherent HHG response and appearance of incoherent radiation. We
generalize our results to phase-matched HHG with mid-infrared drivers,
and determine that a minimum pulse
energy is needed to simultaneously phase match the HHG
process and keep photoelectrons unperturbed by surrounding particles.
Therefore, while previous research showed that HHG efficiency is
independent of the driving pulse energy if other experimental
parameters are scaled accordingly, we find that this rule no longer
applies for high photon energies. Our study thus provides important
guidelines for the laser parameters needed for the generation of high
flux soft x-ray high harmonics.
Distributed chemical detection outside standard coated fibers using Brillouin optical time-domain analysis of cladding mode spectra
Authors: Zehavi Elad , Bernstein Alon , Bashan Gil , Diamandi Hilel Hagai , Sharma Kavita , London Yosef , Hen Mirit , Shemer Keren , Stolov Andrei A. , Li Jie , Zadok Avi
Published: November 2022

Propagation in the cladding modes of standard optical fibers enables
the sensing of chemicals outside the fiber boundary, where light in
the single core mode cannot reach. Coupling to the cladding modes
typically relies on the inscription of permanent gratings, which
restricts the operation of the sensors to point measurements only. In
addition, most applications rely on bare, uncoated fibers, which are
difficult to deploy outside the research laboratory. In this work, we
report the spatially distributed analysis of cladding mode spectra in
a standard, off-the-shelf coated fiber. The inscription of the
gratings, removal of the coating, or other structural modifications
are not required. Coupling is based on Brillouin dynamic gratings: Two
optical pump fields stimulate an acoustic wave, which couples a probe
field to a counter-propagating cladding mode. Spatial mapping is
obtained through time-of-flight analysis: pulsed modulation of one
pump wave and the monitoring of the output probe power as a function
of time. All fields are launched and detected only in the core mode.
The coupling spectrum is sensitive to local changes in the refractive
index of the coating layer, to the third decimal point. The spatial
resolution is one meter. The demonstrated range is a few meters, and
is scalable to hundreds of meters. The technique is used to detect and
monitor the local immersion of a fiber section in acetone. The results
establish a practical method for spatially distributed fiber optic
chemical sensors.
How public can public goods be? Environmental context shapes the evolutionary ecology of partially private goods
Authors: Lerch Brian A. , Smith Derek A. , Koffel Thomas , Bagby Sarah C. , Abbott Karen C.
Published: November 2022

The production of costly public goods (as distinct from metabolic byproducts) has largely been understood through the realization that spatial structure can minimize losses to non-producing “cheaters” by allowing for the positive assortment of producers. In well-mixed systems, where positive assortment is not possible, the stable production of public goods has been proposed to depend on lineages that become indispensable as the sole producers of those goods while their neighbors lose production capacity through genome streamlining (the Black Queen Hypothesis). Here, we develop consumer-resource models motivated by nitrogen-fixing, siderophore-producing bacteria that consider the role of colimitation in shaping eco-evolutionary dynamics. Our models demonstrate that in well-mixed environments, single “public goods” can only be ecologically and evolutionarily stable if they are partially privatized (i.e., if producers reserve a portion of the product pool for private use). Colimitation introduces the possibility of subsidy: strains producing a fully public good can exclude non-producing strains so long as the producing strain derives sufficient benefit from the production of a second partially private good. We derive a lower bound for the degree of privatization necessary for production to be advantageous, which depends on external resource concentrations. Highly privatized, low-investment goods, in environments where the good is limiting, are especially likely to be stably produced. Coexistence emerges more rarely in our mechanistic model of the external environment than in past phenomenological approaches. Broadly, we show that the viability of production depends critically on the environmental context (i.e., external resource concentrations), with production of shared resources favored in environments where a partially-privatized resource is scarce.
Gynecologic problems and healthcare behavior by shift patterns in Korean nursing staff
Authors: Kim Miseon , Kim Ju-Hyun , Jung Yong Wook , Seong Seok Ju , Kim Seon-young , Yoon Hee-Ja , Lee Seung-shin , Kim Hyun-Ju , Ku Boon-sun , Cho Hwa-yeon
Published: November 2022

We aimed to evaluate the clinical impact of shift patterns at work on gynecologic problems and the healthcare behavior of Korean nursing staff. We conducted a web-based survey for over two weeks in September 2021, involving female nursing staff, including nurses, nurses’ aides, and nursing assistants, working in five medical centers. The questionnaire included 40 questions on baseline characteristics, working information, and experiences with gynecologic problems and medical approaches. Overall, 885 nursing staffs participated in the survey, of the 1,904 who received the invitation with an online link of the survey. The response rate was 46.5%. Among the participants responding to all questions, 569 (64.4%) worked two or three shifts and 305 (34.5%) worked full-time. In women rotating two or three-shift patterns, irregular menstrual cycles (21.6% vs. 13.8%, p = 0.005), abnormal menstrual cycles (40.9% vs. 33.8%, p = 0.038), and dysmenorrhea (48.0% vs. 38.4%, p = 0.006) were more frequent than in those who worked full-time. The experience of visiting gynecologic clinics (47.5% vs. 44.1%, p = 0.332) and treating gynecologic conditions (33.4% vs. 29.3%, p = 0.211) did not differ according to the working patterns. However, diagnosis of gynecologic diseases was more frequent in women working full-time (36.4% vs. 29.7%, p = 0.043). The rates of screening (76.1% vs. 57.8%, p<0.001) and human papillomavirus vaccination (55.7% vs. 39.9%, p<0.001) for cervical cancer prevention were higher in women working full-time than in two–three shifts. This study showed that rotating shift work may be related to an increase in gynecologic problems and a decrease in cancer prevention activity among female nursing staff.
An evidence-based approach to assessing the effectiveness of training regimen on athlete performance: Youth soccer as a case study
Authors: Rechenmacher Cam M. K. , Keating Michael , Nichols James D. , Nichols Jonathan M.
Published: November 2022

Athletic performance data are modeled in an effort to better understand the relationship between both hours spent training and a measurement of “commitment” to that training, and improvements in performance. Both increased training time and greater commitment were predicted to produce larger increases in performance improvement, and commitment was predicted to be the more important determinant of improvement. The performance of 108 soccer players (ages 9–18) was quantified over a 10-week training program. Hours spent training ranged from 16 to 90 during the course of the study, while commitment scores ranged from 0.55 to 2.00, based on a scale from 0.00 to 2.40. A model selection approach was used to discriminate among models specifying relationships between training hours and improvement, and commitment and improvement. Despite considerable variability in the data, results provided strong evidence for an increase in performance improvement with both training hours and commitment score. The best models for hours and commitment were directly compared by computing an evidence ratio of 5799, indicating much stronger evidence favoring the model based on commitment. Results of analyses such as these go beyond anecdotal experience in an effort to establish a formal evidentiary basis for athletic training programs.
Weaving a cocoon on the way to aging transcendence: Grounded theory study on aging perception during menopause transition
Authors: Navvabi-Rigi Shahin-Dokht , Mohammadi-Shahboulaghi Farahnaz , Foroughan Mahshid , Momtaz Yadollah Abolfathi
Published: November 2022

During menopause, women experience major changes, including the onset of aging as a natural and inevitable event. The present study aimed to explore and explain the process of aging perception during menopausal transition. This study was a qualitative grounded theory research, which was going to be implemented in 2019–2020 on 18 Baluch women settled in the Sistan & Baluchestan province in South-East Iran and among midlife or older menopause experienced women. Sampling was started first by Purposive sampling, and then it was performed with theoretic sampling. Data analysis was performed according to Corbin and Straus’s approach (2015) in four phases: (1) identifying and developing concepts; (2) analyzing data for the context; (3) entering the process stage into analysis; and (4) integrating categories to build a theory. In this study, seven main categories were obtained: “Sunset of youth”, “aging as the other side of the coin of menopause”, “Weaving a cocoon”, “aging as a mental trap”, “social acceptance”, “aging domino”, and “feeling of transcendence”. It seems that menopause plays an important role in Baluch women’s view toward aging. The practical results of this study can be applied to better understand the middle-aged and older Baluch women’s attitudes toward aging. Also study shows a new evolutionary and situational perspective on the lives of middle-aged menopausal Baluch women. Baluch women in menopause accept the sunset of youth and look forward to experiencing the Feeling of transcendence. Identify and respond to their needs by developing and establishing health policies to change their negative attitudes.
‘Spectaculars’ and the study of popular musicking
Authors: Anderson Claire M.
Published: November 2022

In US popular music textbooks, women’s contributions are often relegated to the margins. This is not because women have been absent from popular music history, but because music scholarship leans towards the study of formal structures and technical ability and away from the emotional or embodied components of music. I advocate for a shift towards studies in popular musicking, both in scholarship and in the classroom. I argue that an emphasis on spectacular performances – collaborative events designed to awe and entertain and which incorporate many elements of musicking – will open doors for discussions of more women artists and artist fanbases largely made up of young women. With an examination of two such spectaculars, I show how music analysis can include extramusical components such as dance, audience, stage presence and even costumes. The study of popular musicking creates space for more women’s stories in scholarship and the classroom.
Becoming and being a DJ: Black female experiences in Ireland
Authors: Kenny Ailbhe
Published: November 2022

This article seeks to gain insights into the musical learning journeys of Black female DJs in Ireland who make up part of the African diaspora and/or Black and Irish community. The DJs’ intersectional and multiple identities are discussed with a view to uncovering how such identities are both fashioned and perceived; projected and silenced; negotiated and dictated. The article presents macro-themes of learning and identity to examine issues relating to music in the home, musical influences, learning processes, in-/non-/formal education and cross-cutting issues relating to gender and ethnicity. These issues are contextually and personally bound, yet speak to the broader complexities, cultures and politics of representation in a male-dominated field. Data are analysed from interviews, media publications and broadcasts to trace three women’s DJ trajectories. Their voices are amplified in literal and metaphorical senses to expand the limited portrayals of their experiences and practices within popular music (education) scholarship.
ANÁLISE SENSORIAL DE MEDUSAS SALGADAS COMO COMPLEMENTO ALIMENTAR
Authors: Sonomura Gabriela , Da Costa Leila Aparecida , Adonai Castro da Silva Marcus , Resgalla Jr. Charrid
Published: November 2022

O aproveitamento de organismos provenientes do bycatch é primordial na atividade pesqueira. Este fato está associado ao seu uso racional, mas acima de tudo pela necessidade de criar um destino favorável a estes recursos disponíveis em grandes quantidades. Para este último item, as medusas são um ponto de destaque já que ocorrem em abundância em todas as modalidades da pesca. No entanto, apesar de terem se tornado fontes de proteínas colagenosas de grande potencial, são totalmente descartadas por não apresentarem interesse comercial no Brasil. Neste contexto, este trabalho propôs dar continuidade aos estudos realizados com o uso de medusas do litoral de Santa Catarina, juntamente com os benefícios que estes espécimes podem apresentar à saúde humana. Para isto, foram utilizadas medusas de bycatch da pesca artesanal de arrasto de fundo de camarão nas regiões de Itajaí, seguido de uma adequação na técnica de salga. Para o produto dessalgado, foram realizadas análises microbiológicas para identificação de possíveis colônias de patógenos, no qual obtiveram resultados negativos. Por fim, uma análise sensorial descritiva foi feita com seis avaliadores, sendo apresentadas três opções de pratos contendo medusas dessalgadas para degustação. Através do perfil de características, os julgadores descreveram os atributos avaliados considerando a aparência, o aroma, o sabor e a textura. A neutralidade no sabor foi avaliada como uma característica positiva, no qual permite que a medusa seja utilizada na presença de outros potencializadores, enquanto o aspecto gelatinoso do organismo não foi bem apreciado, sendo considerado um fator limitante. Destaca-se que os resultados obtidos na descrição da terminologia ultrapassaram as expectativas, apontando uma diversidade de atributos que pode ser obtida e explorada a partir de uma análise de descritores.  Ainda, a preferência dos avaliadores pela versão oriental possibilita o desenvolvimento de uma futura análise de aceitabilidade, que visa introduzir um produto diferenciado no mercado consumidor.Palavras-chaves: 1. Análise Sensorial 2. Recurso Marinho 3. Culinária 4. Água-Viva
Usia Gestasi Sebagai Prediktor Keberhasilan Terapi Antibiotik Empiris pada Infeksi Neonatorum di Rumah Sakit Umum Daerah Dr. Moewardi Surakarta
Authors: Ariefudin Yanuar , Umma Husnia Auliyatul , Nur Fadhilah Tia , Salimo Harsono
Published: November 2022

Latar belakang. Infeksi merupakan penyebab utama kematian ketiga pada bayi baru lahir setelah komplikasi prematuritas dan asfiksia. Pemberian antibiotik empiris yang sama, baik pada neonatal aterm maupun neonatal preterm, dan penggunaan antibiotik empiris yang tetap dalam 10 tahun terakhir, maka dilakukan penelitian prospektif untuk menganalisis usia gestasi sebagai prediktor keberhasilan terapi antibiotik empiris pada infeksi neonatorum.Tujuan. Menganalisis usia gestasi sebagai prediktor keberhasilan terapi antibiotik empiris pada infeksi neonatorum.Metode. Penelitian ini merupakan penelitian kohort prospektif dengan pendekatan uji prognostik. Penelitian dilakukan di High Care Unit (HCU) Neonatus RSUD Dr. Moewardi Surakarta pada bulan April - Desember 2021. Nama pasien, usia gestasi, jenis kelamin, metode persalinan, berat badan lahir, asupan ASI, hasil kultur darah, jenis antibiotik dan terapi suportif dicatat. Uji chi square dilanjutkan dengan uji multivariat regresi logistik digunakan untuk menganalisis data.Hasil. Dari 146 neonatal infeksi, didapatkan 75 neonatal aterm dan 71 neonatal preterm. Kedua kelompok mendapatkan terapi antibiotik empiris. Analisis multivariat regresi logistik menunjukkan hasil usia gestasi dengan nilai p=0,001, terapi suportif dengan nilai p=0,090 dan kewaspadaan isolasi dengan nilai p=0,010. Usia gestasi aterm didapatkan hasil paling signifikan dengan nilai p=0,001 dan odds rasio 0,289 (IK 95%, 0,137 – 0,612).Kesimpulan. Usia gestasi merupakan prediktor keberhasilan terapi antibiotik empiris pada infeksi neonatorum.