bluuebunny/crossref_metadata_2025 huggingface dataset:
Efficacy of educational strategies in patient involvement for safety in care: a systematic review
Authors: Luiz Raíssa Bianca , Estevam Layara Oliveira , Raponi Maria Beatriz Guimarães , Felix Márcia Marques dos Santos , Barbosa Maria Helena
Published: November 2022

ABSTRACT Objective To evaluate the effectiveness of educational strategies in the involvement of hospitalized adult patient for safety in care. Method Systematic review carried out by searching for experimental and quasi-experimental studies, published from January/2010 to December/2021, in PubMed®, Cochrane Library CENTRAL, Scopus, Web of Science, LILACS, CINAHL and EMBASE. Results Twelve studies were included to involve the patient in safe care practices, five (41.7%) experimental and seven (58.3%) quasi-experimental. Different educational strategies were adopted in the articles included: verbal guidance, books, leaflets and folders (n=4; 33.3%); videos, e-books and electronic applications (n=5; 41.7%); poster, leaflets and video (n=3; 25%). Four experimental studies had a high risk of bias (80%) and all quasi-experimental studies had a low risk of bias (100%). Conclusion The use of educational strategies proved to be effective in involving the patient in safe care practices. Considering the heterogeneity between studies, it is recommended carrying out future research.
HOW MUCH TIME DOES TIME HAVE? THE DAILY LIVES OF CHILDREN DURING COVID-19 PANDEMIC
Authors: Santana Juliana Prates , Lordelo Lia da Rocha , Férriz Adriana Freire Pereira
Published: November 2022

ABSTRACT Articulating the Social Studies of Childhood and a contemporary approach in Developmental Psychology, this study aimed to investigate the experience of children from Salvador, Brazil, and its metropolitan region, concerning their organization of time during Covid-19pandemic; particularly, how children organize their days, how they perceive the passage of time, and how they have been managing free and institutionalized time within the domestic space. Results show a significant increase in the time spent with electronic devices and screens, a reduction is physical activities, and the feeling of boredom by some children. This feeling was preceded by the reorganization of their weeks with the main activities they usually did before the pandemic – school, extracurricular, and leisure activities – in the remote system.
CUARENTA TAREAS PARA LA CUARENTENA: INFANCIA Y TAREAS ESCOLARES DURANTE EL CONFINAMIENTO
Authors: Rodríguez-Pascual Iván , Andrés-Candelas Mario , Muñoz Marta Martínez , Crespo Gabriela Velásquez
Published: November 2022

RESUMEN A partir del proyecto Infancia Confinada, se muestra la percepción que la población infantil española tiene sobre las tareas académicas durante el confinamiento, apuntando a sus implicaciones en términos de desigualdad y vulnerabilidad. Constatamos, a través de un análisis de regresión logística, que estas pueden haber constituido una sobrecarga para aquellos sujetos que manifiestan menor satisfacción vital y peor estado de salud, perciben en mayor medida la fragilidad económica de su familia y han convivido durante el confinamiento con padres que pudieron dedicarles menos tiempo.
“NÓIS” É PONTE E ATRAVESSA QUALQUER RIO: NOTAS SOBRE MULHERES, CRIANÇAS, COLETIVOS PERIFÉRICOS E O COMUM (OU, QUANDO A PANDEMIA É APENAS MAIS UM ELEMENTO)
Authors: Gobbi Marcia
Published: November 2022

RESUMO O artigo tem como objetivo apresentar reflexões sobre relações entre mulheres e crianças ligadas a coletivos periféricos existentes nos extremos das zonas Sul e Leste da cidade de São Paulo que sofreram algumas alterações durante a pandemia da Covid-19. Para tanto, aproxima-se do conceito de comum para definir coletivos, em virtude da similitude de alguns princípios. Após mapeamento para conhecer suas regiões de atuação, foram usados entrevistas, podcasts e sites como recursos que possibilitaram compreender propostas e práticas desses coletivos. Nas conclusões, reitera-se o papel das ações empreendidas pelas mulheres em relação às crianças como inspiradoras para projetos de sociedade não hierarquizados e comunitários.
INSERVICE TEACHER EDUCATION OF THE “MAIS PAIC” PROGRAM FROM THE VIEWPOINT OF EDUCATIONAL MANAGERS AND TEACHERS
Authors: Lopes Jayane Mara Rosendo , Sousa Leandro Araujo de , Pontes Junior José Aírton de Freitas
Published: November 2022

This research aimed analyze the inservice teacher education of the “Mais Paic” program from the viewpoint of educational managers and lower secondary educational teachers. We used a descriptive and qualitative approach. Educational managers, Mathematics and Portuguese teachers were interviewed. We analyzed the interviews with content analysis. Our results show positive and negative characteristics of the inservice teacher education. Furthermore, improvement and harmful aspects were indicated by the participants. We discuss their viewpont and the implications for inservice teacher education.
ROL DE LA AUTOFAGIA EN LA ETIOPATOGÉNESIS DEL CÁNCER ORAL. REVISIÓN SISTEMÁTICA EXPLORATORIA
Authors: López Francisca , Moreno Arelys , Reyes Silvana , Sánchez Marcelo
Published: November 2022

En esta revisión sistemática exploratoria, presentamos la evidencia registrada en la literatura, de que la autofagia puede generar una acción tanto procáncer como anticáncer, actuando a través de diversos mecanismos en los cuales el proceso de autofagia puede estar aumentado, disminuido o alterado, mediante la activación de vías de señalización intracelular. En la actualidad, hay evidencia suficiente que avala la asociación entre autofagia y distintos tipos de cáncer, sin embargo, no hay una revisión que reúna los diversos mecanismos por los cuales el proceso autofágico participa en su desarrollo y/o supresión. Se logro evidenciar que existen variados mecanismos por los cuales la autofagia participa en el desarrollo de la carcinogénesis oral, influyendo tanto en la inhibición como en la producción de cáncer. Es de gran importancia aumentar el conocimiento acerca de este proceso, debido a que podría ser utilizado como una herramienta valiosa en el tratamiento de esta enfermedad.
CONCEPÇÕES DE GESTÃO ESCOLAR DEMOCRÁTICA: ESTUDO FENOMENOGRÁFICO COM DIRETORES DE ESCOLAS PÚBLICAS
Authors: Amaro Rubens de Araújo Amaro , Schunk Luciana , D'Angelo Márcia
Published: November 2022

Diante da escassez de estudos empíricos sobre gestão escolar democrática no país, o objetivo dessa pesquisa é analisar, à luz da fenomenografia, as diferentes concepções de gestão escolar democrática e suas implicações nas práticas de gestão dos diretores de escolas públicas. A produção de dados se deu por meio de entrevistas individuais em profundidade com 19 diretores de escolas municipais de ensino fundamental. Os dados foram analisados a partir de protocolo fenomenográfico consagrado na literatura. Foram identificadas três diferentes concepções de gestão escolar democrática: (1) como cumprimento de papéis; (2) como insumo para a tomada de decisão; (3) como atendimento das necessidades da comunidade. A principal contribuição desta pesquisa é mostrar como essas concepções induzem os diretores escolares a diferentes práticas de gestão democrática. Outra contribuição é oferecer uma interpretação alternativa à atuação dos burocratas de nível de rua e outros atores que modificam uma política pública ao implementá-la. Os achados também mostram que a promoção da participação, por meio do diálogo, fomenta a autoria organizacional. Finalmente, apresenta-se a fenomenografia como método de investigação promissor para o campo da gestão escolar.
IDENTIFICATION OF TRANSPORT PARAMETERS FOR THE SOLUTE FILTRATION THROUGH POROUS MEDIA WITH CLOGGING
Authors: Maryshev Boris S. , Khabin Mikhail R. , Evgrafova Anna V.
Published: November 2022

The transport of highly concentrated solutions in porous media was studied both numerically and experimentally. For numerical modeling we used a mobile-immobile (MIM) approach that considers clogging phenomenon. The impurity transition between the mobile and immobile phases was defined by second-order Langmuir kinetics. Kozeny-Carman expression modeled the clogging. The model has four phenomenological parameters which cannot be measured directly. These parameters were identified by minimization of the cost function, which is the squared distance between experimental and numerical data. Dependencies of concentration and mass flux at the outlet were analyzed. Twenty-five different experiments were conducted, and it was shown that transport parameters do not depend on impurity concentration or pressure drop between the ends of the column.
Factores determinantes del proceso de creación y consolidación de empresas
Authors:   Universidad Cooperativa de Colombia, Arango Benjumea Jhon Jaime
Published: November 2022

El presente texto es el resultado de una investigación realizada en Medellín sobre los factores que influyen en la creación y la consolidación de una empresa. Los resultados aquí presentados tienen el propósito de animar a los emprendedores para que continúen con su proyecto de vida empresarial y a las instituciones y al Estado para que apoyen el fortalecimiento de los programas de creación y consolidación de empresas. El emprendimiento se ha establecido en los últimos tiempos como una alternativa viable para el desarrollo y el crecimiento económico y social de las regiones, por eso, el interés de estudiar aquellos factores que mayor relevancia tienen en la creación y la consolidación de una empresa. Si bien el estudio se centró en el contexto de Medellín, los resultados presentados podrán servir de base para el fortalecimiento de los programas de emprendimiento en otros contextos nacionales, regionales e internacionales, mediante la canalización de mejores esfuerzos y recursos para que el proceso de creación y consolidación de las empresas se ajuste en mejor medida a las características sociales, económicas y culturales de cada localidad en particular. El texto se desarrolla en cinco temas que se presentan en cinco capítulos que respectivamente son casos de emprendimiento, aspectos conceptuales del proceso de creación de empresas, resultados estadísticos de la creación de empresas, aspectos conceptuales del proceso de consolidación de empresas y resultados factoriales de la consolidación de empresas. En la parte final del texto se presentan las conclusiones y las recomendaciones. Como contribución y conclusión, los factores relevantes en la creación de empresas son los contactos, la educación, el capital y la capacidad de negociación. En cuanto a la consolidación de empresas los factores más relevantes son el riesgo, la perseverancia, la estrategia, el personal y el crecimiento.
KARAKTERISASI MATERIAL INSULASI KABEL LISTRIK TEGANGAN RENDAH DARI PRODUK LOKAL PASCA IRADIASI GAMMA
Authors: Hutagaol Antonio Gogo , Bayquni Muhammad Ilham
Published: November 2022

KARAKTERISASI MATERIAL INSULASI KABEL LISTRIK TEGANGAN RENDAH DARI PRODUK LOKAL PASCA IRADIASI GAMMA. Penelitian ini ditujukan untuk mempelajari pengaruh radiasi gamma terhadap karakter polimer semi kristalin pada material insulasi kabel listrik tegangan rendah dari produk lokal, terkait penggunaannya di fasilitas dengan radiasi gamma tinggi. Sampel uji diiradiasi menggunakan perangkat Gamma Cell dengan dosis radiasi sebesar 25, 50, 100, 200, 400 dan 800 kGy. Derajat kristalinitas dan komposisi senyawa dari sampel uji dianalisis dengan uji XRD dan dikarakterisasi menggunakan FTIR. Berdasarkan uji XRD yang dilakukan, tidak teramati adanya perbedaan signifikan pada pola difraksi antara sampel uji non iradiasi maupun sampel uji iradiasi dengan variasi besar dosis. Hal ini mengindikasikan tidak terdapat perubahan fase mayor dari senyawa kristalin yang terkandung dalam sampel uji terkait. Adapun derajat kristalinitas dari sampel uji cenderung menurun seiring meningkatnya dosis radiasi yang diberikan. Hasil analisis FTIR menunjukkan adanya perbedaan transmittance yang fluktuatif antar sampel uji dengan dosis radiasi gamma yang berbeda juga dengan sampel uji non-iradiasi gamma. Adanya spektra yang semakin melebar di 400 kGy dan 800 kGy, pada wavenumber 3369 – 3370 cm-1, hal ini mengindikasikan adanya gugus O-H stretch. Pengujian lebih lanjut diperlukan untuk menguatkan identifikasi terhadap gugus fungsi, penentuan senyawa organik, maupun evaluasi terhadap karakter mekanik sampel uji yang sekaligus diperlukan untuk mengonfirmasi dugaan adanya gangguan terhadap asosiasi polimer-plasticizer.Kata kunci: Polimer semi kristalin, irradiasi gamma, derajat kristalinitas, perubahan kimia
STUDI PENGARUH PENAMBAHAN YTTRIUM DAN PERLAKUAN PANAS BETA TERHADAP KETAHANAN HIDROGEN PADUAN ZIRCALOY-4-0,1%Mo PADA TEMPERATUR 600°C DAN 800°C
Authors: Alfatar Ajra , Basuki Eddy Agus , Prajitno Djoko Hadi
Published: November 2022

STUDI PENGARUH PENAMBAHAN YTTRIUM DAN PERLAKUAN PANAS BETA TERHADAP KETAHANAN HIDROGEN PADUAN ZIRCALOY-4-0,1%Mo PADA TEMPERATUR 600°C DAN 800°C. Energi listrik merupakan sumber energi yang banyak digunakan dan dibutuhkan oleh manusia. Sehingga kebutuhan energi listrik ini akan meningkat seiring bertambahnya jumlah populasi manusia. Pembangkit Listrik Tenaga Nuklir (PLTN) merupakan salah satu solusi dari persoalan tersebut. Salah satu komponen penting reaktor nuklir yaitu kelongsong bakar nuklir biasanya menggunakan material berupa paduan zirkonium, namun penggunaan paduan ini dalam waktu yang lama akan rentan terhadap penggetasan akibat penetrasi hidrogen. Serangkaian percobaan dilakukan untuk mengetahui pengaruh penambahan yttrium dan perlakuan panas beta terhadap ketahanan hidrogen dan sifat mekanis paduan Zircaloy-4-0,1%Mo-xY (x=0 wt%; 0,5 wt%; 1 wt%). Penambahan yttrium menyebabkan peningkatan jumlah presipitat yang diduga adalah α-Y sekaligus meningkatkan kekerasan paduan baik pada paduan as cast maupun perlakuan panas beta. Perlakuan panas beta menurunkan kekerasan paduan akibat peningkatan jumlah fasa β-Zr. Peningkatan ketahanan hidrogen dapat dilakukan dengan penambahan yttrium karena bertindak sebagai penstabil fasa β-Zr. Sama halnya dengan perlakuan panas beta yang dapat meningkatkan ketahanan hidrogen dengan metode yang sama yaitu meningkatkan jumlah fasa β-Zr sehingga jumlah hidrogen yang dapat larut meningkat. Penambahan 1 wt% Y pada paduan zircaloy-4-0.1%Mo dengan perlakuan panas beta menunjukkan ketahanan hidrogen yang paling baik dengan ketebalan 6,24 μm pada temperatur 600°C dan 545,5 μm pada temperatur 800°C.Kata kunci: Zircaloy-4, ketahanan hidrogen, variasi yttrium
ESTIMASI PANAS GAMMA PADA PRODUKSI RADIOISOTOP Lu-177, Ir-192, DAN Au-198 DI TERAS MOLIBDENUM RSG-GAS
Authors: Riskiana Dewi Nur , Rohanda Anis , Abdullatif R Farzand
Published: November 2022

ESTIMASI PANAS GAMMA PADA PRODUKSI RADIOISOTOP Lu-177, Ir-192, DAN Au-198  DI TERAS MOLIBDENUM RSG-GAS. Panas gamma (Gamma heating) merupakan isu penting terkait keselamatan fasilitas iradiasi suatu reaktor dan sampel iradiasinya. Panas gamma dihasilkan dari interaksi energi gamma dengan material target. Energi gamma yang dihasilkan dari reaktor memiliki karakteristik energi gamma yang berbeda yang salah satunya dipengaruhi oleh jenis bahan bakar (jenis teras). Uranium molibdenum (UMo) merupakan bahan bakar masa depan yang memiliki beberapa keunggulan dibandingkan uranium oksida (UO2) dan silisida (USi) salah satunya dapat meningkatkan operasi reaktor. Untuk itu dilakukan studi komputasi panas gamma RSG-GAS dengan bahan bakar UMo pada beberapa proses produksi radioisotop seperti radioisotop Lu-177, Ir-192, dan Au-198. Penelitian ini menggunakan code ORIGEN untuk menghitung energi gamma yang dihasilkan untuk jenis bahan bakar UMo. Estimasi panas gamma menggunakan program Gamset, suatu program didesain dan sudah teruji untuk menghitung panas gamma di RSG-GAS. Hasil perhitungan panas gamma berbahan bakar UMo di RSG-GAS dalam kisaran 4,85 W/g ~ 8,69 W/g . Hasil ini lebih kecil dibandingkan dengan panas gamma pada uranium silisida (USi) yaitu sekitar 9,27 W/g ~ 13,3 W/g. Radioisotop Lu-177 memiliki panas gamma terbesar sekitar 8,69 W/g, yang diikuti oleh Au-198 dan Ir-192 yang masing-masing sebesar 5,89 W/g dan 7,12 W/g. Panas gamma pada ketiga radioisotop yang diproduksi oleh RSG-GAS berbahan bakar UMo tidak melebihi panas gamma maksimum (20 W/g) yang telah ditentukan sehingga dapat diartikan aman untuk reaktor dan sampel.Kata kunci: Panas gamma, UMo, RSG-GAS, radioisotop
STUDY OF FISSION GAS BUBBLES AND INTERACTION LAYER ON IRRADIATED U3Si2-Al DENSITY OF 4.8 gU/cm3
Authors: Sihotang Juan Carlos , Ajiriyanto Maman Kartaman , Putri Anditania Sari Dwi , Nurlaily Ely , Junaedi Junaedi , Br Ginting Aslina , Supardjo Supardjo
Published: November 2022

STUDY OF FISSION GAS BUBBLES AND INTERACTION LAYER ON IRRADIATED U3Si2-Al DENSITY OF 4.8 gU/cm3. Uranium-silicide compound fuel dispersed in aluminium matrix (U3Si2-Al) have been used in a large number of research reactors around the world because of its excellent behavior under irradiation. This fuel also provides high uranium density with typical fuel loading up to 4.8 gU/cm3 to compensate for the reduced fissile amount in LEU. To improve the density of current U3Si2-Al (2.96 gU/cm3) used in Indonesian GA Siwabessy Multipurpose Research Reactor, U3Si2-Al dispersion fuel plate with density of 4.8 gU/cm3 (U235 ∼19.75%) had been irradiated in RSG GAS for 175 days at 15 MW power to burnup level of approximately 40%. The characterization was performed using SEM-EDS and optical microscope to study microstructure of the irradiatted fuel, largely the fission gas bubbles and the interaction layer between U3Si2 fuel and Al matrix. The average diameter of the bubbles with diameter from 0.06 to 0.55 µm was 0.21 µm. The interaction layer was identified as U(Al,Si)2,3 with thickness of approximately 1.5 µm. The relatively small fission gas bubbles and the interaction layer didn’t cause swelling on the fuel and the overall performance of the fuel plate was very good.Keyword:  LEU, uranium-silicide, post-irradiation examination, interaction layer, fission gas bubbles.
Roadmap to the bioinformatic study of gene and protein phylogeny and evolution - a practical guide v2
Authors: not provided florian.jacques
Published: November 2022

Developments in sequencing technologies and the sequencing of an ever-increasing number of genomes have revolutionisedstudies into biodiversity and organismal evolution. This accumulation of data has been paralleled by the creation of numerous public biological databases through which the scientific community can mine the sequences and annotations of genomes, transcriptomes, and proteomes of multiple species. However, to find the appropriate databases and bioinformatic tools for respective inquiries and aims can be challenging. Here, we present a compilation of DNA and protein databases, as well as bioinformatic tools for phylogenetic reconstruction and a wide range of studies on molecular evolution. We provide a protocol for information extraction from biological databases and simple phylogenetic reconstruction using probabilistic and distance methods, facilitating the study of biodiversity and evolution at the molecular level for the broad scientific community.
EFFECT OF PLANT DENSITY ON YIELD AND QUALITY OF PEANUT (Arachis hypogaea L.) CULTIVARS
Authors: YILMAZ Mustafa , JORDAN David Lindley
Published: November 2022

Plant density can have a major impact on peanut (Arachis hypogaea L.) yield. Information is limited in the Eastern Mediterranean Transition Region of Turkiye on growth, development, and yield of peanut cultivars based on plant density. To address this limitation, the cultivars Aysehanim, Rigel, Halisbey, Masal, and NC 7 were established in a single row planting pattern consisting of rows spaced 70 cm apart with an inter-row plant distance of 15 cm (95.000 plants ha-1) versus a twin row planting pattern consisting of rows spaced 20 cm apart on 90 cm centers with an intra-row distance of 15 cm (148.000 plants ha-1). The interaction of cultivar × plant density was significant for most variables. Irrespective of cultivar, establishing a plant population of 148.000 plants ha-1 in the twin row planting pattern resulted in greater pod yield than the single row planting pattern with a plant density of 95.000 plants ha-1. Pod yield was similar for Rigel, Masal, and NC 7 in the twin row planting pattern and exceeded that of Aysehanim and Halisbey. Conversely, yield of Rigel and Halisbey was similar in the single row pattern and exceeded yield of Aysehanim and NC 7.
Distributed Leadership and Inclusive schools
Authors: Tejeiro Federico
Published: November 2022

This article tries to answer the question of whether distributed leadership contributes significantly to the development of an inclusive school. For this, a systematic review of the literature has been carried out, based on the PRISMA strategy, of articles from 2011 to 2021 that describe 35 schools with distributed leadership. The findings reflect that there is a relationship between distributed leadership, promoted by the principal, and the achievement of an inclusive school. We found that elements of distributed leadership such as cooperative teamwork and decision-making lead to a focus on student-centred educational approaches, encouraging their participation, their families’ participation, and sometimes, the need to count on people outside the school itself. It is also noted that distributed leadership promotes inclusive teacher training. On the other hand, some barriers arise that hinder the participation of students and their families. It concludes with the need to train management teams in distributed leadership and promote legislative changes to favour the participation of all students without exceptions.
Effects of active static stretching in a patient with COPD after complication by COVID-19, case report
Authors: Nascimento Folha Pablo , Pereira Frank Bacurau Reury
Published: November 2022

Background: COPD, called Chronic Obstructive Non-transmitted Pulmonary Disease, is a disease that causes severe sequelae in the respiratory system, which in combination with other types of viruses such as covid-19 aggravates the disease, with major effects on the locomotor system due to saturation instabilities. The main victims of the disease are elderly smokers and ex-smokers of both sexes. In more severe cases, there is a need for continuous treatment with oxygen therapy, limiting the quality of life and physical activity of the elderly. Objective: Physical activity is an alternative non-pharmacological treatment to help the recovery of the individual with severe COPD, minimizing the complications of the disease. Method: The study aims to describe the case of a 77-year-old elderly man, ex-smoker for 17 years, with severe sequelae post COPD-19 in the respiratory system, dependent on oxygen therapy for great instability of mean saturation below 70%, with reflexes on the locomotor system, having difficulties in locomotion. In this case, to keep him active, active static stretching exercises were proposed for five consecutive days. Results: After five consecutive days of active stretching, the results were positive, increasing saturation by an average of 1.75%, reaching 89.79% without the help of oxygen therapy, which was enough to reduce dyspnea, wean him off oxygen therapy, and improve his mobility and quality of life. Conclusion: that active static stretching is beneficial for severe cases of COPD, minimizing complications and reducing the use of oxygen therapy.
CINTA RAHWANA DALAM KACAMATA DJOKO PADA PUISI “PENGAKUAN RAHWANA”
Authors: Pelangi Alicia Putri
Published: November 2022

ABSTRAK: Pada puisi Pengakuan Rahwana, dari kumpulan puisi berjudul Kemelut Cinta Rahwana karya Djoko Saryono, menarik perhatian penulis mengenai problematik cinta Rahwana pada Sinta tentang apa cinta sebenarnya? Metode kerja penelitian berupa penyajian hasil analisis dimana sikap Rahwana membuktikan mampu mengorbankan apapun, serta menghormati Sinta dan bukannya dominasi membuktikan kesucian cintanya. Tetapi, tindakan serta obsesinya tidak termaafkan untuk apa yang ia lakukan kepada Sinta. Dan itu bukanlah sebuah cinta, melainkan perasaan menipu diri janjinya memuliakan Widowati. Kata Kunci: Cinta, Rahwana, Ramayana.
True Stress-Strain Behavior of Al-based Cast Automotive Alloy Under Different Ageing Conditions and the Effect of Trace Zr
Authors: Shoummo Mashiur Rahman , Khan Akib Abdullah , Kaiser Mohammad Salim
Published: November 2022

A thorough investigation has been carried out on the Al-12Si-1Mg-1Cu-1Ni automotive alloy considering different properties, specially mechanical properties associated with true stress and true strain with Zr addition of trace amount. A commercially available piston is melted to produce the alloy, and trace amount of Zr is added to make another. The base alloy along with the Zr added alloy had been applied to homogenization, solution treatment, quenching, and ageing in order to get the age-hardening response. The alloys have been heat-treated at 25 ºC, 200 ºC, and 300 ºC, respectively, for four hours for attaining the under, peak and over-aged states, respectively. During ageing, Al2Cu and Mg2Si phases are formed in the aluminium matrix leading to peak-aged strength, which is reduced at over-aged state because of coarsening of precipitation and recrystallizing, shown by the tensile and hardness properties. When Zr is added to the alloy, Al3Zr phases appear while casting and heat-treatment, resisting the drop of strength at over-aged state. It is visible in the stress-strain diagram that at over-aged conditions, the alloy with trace Zr shows improved strength and ductility. In the micrographs of Zr added alloy, finer distributed grains are visible through the grain refinement of Zr, which also prevents recrystallization at over-aged conditions. The homogeneity of the grains as a result of the Zr addition's microstructural change was further confirmed by fractography. It is clear that adding Zr to such alloys does not greatly increase their strength, but it does restrict the declining of strength by preventing the production of thermally stable Al3Zr precipitates, which coarsens the resisting behavior of various intermetallics in the thermally damaged alloy.
Стереотаксическая лучевая терапия при почечно-клеточном раке. Опыт и непосредственные результаты
Authors: Степанович Е. А. , Демешко П. Д. , Поляков С. Л. , Минайло И. И.
Published: November 2022

Цель: Оценить выживаемость пациентов, страдающих почечно-клеточным (ПКР) раком I ст., подвергнутых стереотаксической аблационной лучевой терапии (САЛТ).

Материал и методы: В исследование включены 22 пациента, которым в РНПЦ ОМР им. Н. Н. Александрова в период 2018–2022 гг. была проведена САЛТ по поводу впервые выявленной опухоли почки. Общее число облученных опухолей составило 25. Критериями включения в исследования явились: рак почки I стадии, наличие противопоказаний к хирургическому лечению, или отказ от хирургического лечения, а также высокий риск развития послеоперационных осложнений. В исследование включались пациенты с размером образований ≤ 5 см. Лечение осуществлялось на аппарате TrueBeam STx (Varian Medical Systems, США). Предписанная доза составила 48 Гр за 4 фракции, биологически эффективная доза (BED) α / β 3 Гр = 240 Гр, BED α / β 10 Гр = 105 Гр. Конечными точками исследования являлись кумулятивная инцидентность (КИ), скорректированная (СВ) и общая выживаемость (ОВ).

Результаты: В 24 случаях при первичном контроле был достигнут локальный контроль заболевания (в 2 в виде полной регрессии, в 15 в виде стабилизации заболевания, в 7 случаях — частичная регрессия опухоли). У 1 пациента был отмечен продолженный рост опухоли и дальнейшее системное прогрессирование заболевания. При оценки локального контроля, медиана наблюдения которого составила 24 месяца, 4-летняя кумулятивная инцидентность составила 4,2 %. Вместе с тем, у 2 пациентов имело место прогрессирования заболевания с развитием отдаленных метастазов, безметастатическая выживаемость составила 86,2 %. За период наблюдения (медиана 24 месяца) умерло 3 человека, все — от причин, не связанных с раком почки. 4-летняя скорректированная выживаемость составила 100 %, общая выживаемость — 85,2 %.

Выводы: Полученные предварительные результаты свидетельствуют о том, что стереотаксическая лучевая терапия может быть использована у неоперабельных пациентов, однако необходимо более глубокое изучение отдаленных результатов после проведенного лечения на большей когорте пациентов.
Особенности селекции пациентов для метастаз-направленной терапии при олигометастатическом РПЖ: можно ли обойтись без системного лечения?
Authors: Волкова М. И. , Аль-Акел И. С.
Published: November 2022

Интенсификация первой линии терапии мГЧРПЖ, диагностированного de novo, привела к значимому увеличению ОВ этой категории больных. Стандартом лечения олигометастатического рака предстательной железы являются комбинации АДТ с антиандрогенами второго поколения. Совершенствование методов диагностики привело к росту доли олигометастатического рака предстательной железы (ОМРПЖ) среди впервые выявленных больных и пациентов, ранее получавших лечение. Растет доказательная база, подтверждающая позитивную роль локального лечения первичной опухоли при диссеминированном раке простаты, однако необходимы данные рандомизированных исследований для определения показаний к циторедуктивным манипуляциям. Метастаз-направленная терапия демонстрирует многообещающие результаты, однако уровень доказательной базы низок, и локальное лечение олигометастазов пока остается экспериментальным методом лечения, требует дальнейшего изучения в статистически значимых группах.
Состав и фенотип опухолевой стромы как маркер прогноза заболевания
Authors: Ковалева О. В. , Подлесная П. А. , Петренко А. А. , Грачев А. Н.
Published: November 2022

Рассматривая микроокружение опухоли, исследователи отмечают большое количество типов клеток, его составляющих. Изучаются различные типы клеток, начиная от стромальных фибробластов и клеток иммунной системы, заканчивая эндотелиальными клетками и адипоцитами. Однако, несмотря на большое количество исследований, использование не стандартизированных маркеров стромальных клеток и подходов в оценке прогноза заболевания до сих пор не привели к их использованию в рутинной клинической практике. Для многих солидных опухолей неотъемлемой составляющей опухолевой стромы является резидентный микробиом, способный в значительной степени повлиять на характер активации иммунокомпетентных клеток микроокружения и анализ состава которого, на сегодняшний день также предлагается использовать в качестве прогностического маркера. В настоящем обзоре литературы проанализирована информация по микробиому и клеточному составу и фенотипу иммунологической составляющей опухолевой стромы новообразований легкого, механизмам их взаимодействия и влиянию этого взаимодействия на прогрессию опухоли. А также изучена возможность их использования для оценки прогноза заболевания и в качестве мишеней для терапии.
Soil physical quality influenced by winter plants
Authors: Goulart Machado Rafael , Ferreira Franco Jean , Hahn Leandro
Published: November 2022

The biomass production by cover plants provides soil protection against erosion and weed control in the winter period, while the effect of cover crops on the parameters of physical soil quality helps in root growth and water storage. The objectives of the present study were to evaluate the influence of winter plants on the physical quality of the soil. The experiment consisted of unifactorial treatments, composed of different winter plants: vetch (Vica sativa L.), forage radish (Raphanus sativus L.), black oat (Avena strigosa Schreb.), rye (Secale cereale L.), wheat (Triticum aestivum L.) and control treatment. The experimental design was randomized blocks, with four replications per treatment. The parcels consisted of 34 lines implanted with a disc seeder and spaced 17 cm and 10 m long, comprising an area of ​57,80 m2 per parcel. Sowing densities were 40 kg ha‑1 for vetch, 20 kg ha-1 for forage radish, 60 kg ha-1 for rye, 150 kg ha-1 for wheat and 90 kg ha-1 for black oat. The control treatment consisted of the vegetation that emerged spontaneously. The parameters evaluated were plant green mass, weed occurrence, apparent density, gravimetric moisture and soil penetration resistance. With the vetch cultivation there was a reduction in the density of the soil in its surface layer, compared to the control treatment and the other cover crops. Wheat increased gravimetric soil moisture retention. Forage radish was superior to the other cover crops in terms of biomass production, totaling 59.91 t ha-1, as well as being the only cover crop that reduced soil penetration resistance, in the layer from 0 to 40 cm of ground. Vetch reduced the density of the soil in its surface layer, and also the resistance to penetration, from 21 cm of depth. Compared to the control treatment, cover crops were efficient in suppressing weed growth.
Sanitary and physiological quality of bean seeds treated with Trichoderma spp.
Authors: Silva Sarzi Janaina , Brião Muniz Marlove Fátima , Rabuske Jéssica Emilia , Da Silva Cruz Couto Leonardo Fellipe , Strahl Marisa Ana , Da Silva Martello Laís
Published: November 2022

The presence of pathogens associated in the bean seeds can represent great risks for the development of the crop. Thus, the seed treatment is essential, and the use of antagonistic microorganisms is an effective tool for the control of various pathogens. Therefore, the objective of the study was to evaluate the sanitary and physiological quality of bean seeds treated with spore suspension and culture filtrates of Trichoderma spp. and the effect of the antagonist on the health quality of bean seeds inoculated with Fusarium oxysporum f. sp. phaseoli and Macrophomina phaseolina. For this, five Trichoderma spp. isolates were used in the form of culture filtrate and spore suspension. Sanity tests were carried out, sanity with inoculation of F. oxysporum f. sp. phaseoli and M. phaseolina and germination test by the paper roll incubation method. The spore suspension of Trichoderma spp. obtained the highest percentage of reduction in the incidence of the pathogen in relation to the culture filtrates, in the seed health tests. Culture filtrates of isolates Eco, TR4 and SC were the most promising ones in relation to the analysis of growth and dry mass of seedlings.
Antioxidant property of “Sweet Grape” tomatoes treated with heat shock
Authors: Cordeiro Noélle Khristinne , Costa Braga Gilberto , Carvalho Jeferson Carlos , Souza Oliveira Shirlene
Published: November 2022

Postharvest conservation methods such as heat shock can increase the nutritional profile of fruits, inducing greater accumulation of antioxidants that participate in the physiological maintenance of fruits. The objective of this work was to evaluate the antioxidant properties of “Sweet Grape” tomatoes treated with heat shock in pre-storage. “Sweet Grape” tomatoes were heat shocked in hot water (45°C) for 10 min. and stored at room temperature for 9 days. β-carotene, ascorbic acid, total phenolic compounds, and antioxidant activity (DPPH, ABTS, and FRAP) were evaluated every 3 days. The pulp and skin of the treated tomatoes had higher β-carotene content than the control during storage, according to the findings. The content of total phenolic compounds in the pulp reduced, regardless of the treatment. There was a reduction of ascorbic acid, but with significantly higher values ​​in the fruits treated on the third and sixth days of storage. The DPPH antioxidant activity of the pulp decreased, regardless of the treatment. In the skin there was a significant effect of the treatment until the sixth day. There was no variation in the ABTS antioxidant activity of the pulp of the treated tomatoes. There was no significant effect of heat shock on the FRAP antioxidant activity of the pulp until the sixth day. Heat shock promoted an increase in β-carotene in tomato skin, which was related to increases in its DPPH antioxidant activity. The heat shock treatment promoted greater retention of ascorbic acid in the fruit, but it was not able to avoid its reduction during storage. The tomatoes’ antioxidant biochemical response to heat shock is most expressed in their skin.
Leaf pigments in cauliflower cultivated with different water conditions and silicon applications
Authors: Soares Wenneck Gustavo , Saath Reni , Rezende Roberto , Villa e Vila Vinicius , Crepaldi de Faria Nocchi Raiana , Maldonado da Silva Lucas Henrique
Published: November 2022

Environmental factors and crop management can influence the characteristics of plant morphology and physiology, altering photosynthetic efficiency and mass accumulation. The study aimed to analyze the contents of leaf pigments in cauliflower cultivated under different conditions of water availability and silicon (Si) applications. The experiment was carried out in a protected environment in the city of Maringá-PR. A randomized block design, in a 3x4 factorial scheme, with three replacement conditions [40, 70 and 100% of crop evapotranspiration (ETc)] and four Si doses (0, 50, 100 and 150 kg ha-1), with four repetitions. The cauliflower cultivation, cultivar Sharon, was carried out in dystroferric RED NITOSOL. Daily evapotranspiration was determined with a constant level water table lysimeter and water replacement was performed with drip irrigation. Si was applied in split doses in three applications (initial, intermediate and final phases). At flowering, leaf tissue from the upper third of the plant was collected, with pigment extraction performed with pure acetone and determination in a spectrophotometer. At harvest, the leaf area of ​​the plants was determined. Data were subjected to analysis of variance and regression analysis. Cauliflower crop under water-deficient reduces leaf area development and alters chloroplast pigments dynamics. Silicon use in the soil increases leaf development, chlorophyll a and b contents, and reduces carotenoids concentration. Under water stress conditions, silicon addition to the soil improves cauliflower performance.
Micronutrient nutrition in sugarcane: a brief review
Authors: Rodrigues da Silva Luiz Daniel , Ferreira de Lima Cruz José Manoel
Published: November 2022

Sugarcane is a crop of worldwide economic value used in sugar, electricity, and alcohol production. This review demonstrates the importance of the main micronutrients and their respective effects on the development and yield of sugarcane. Micronutrient deficiency is one of the limiting factors in sugarcane productivity in producing regions. This deficit is related to several aspects, such as fertilizer use with low micronutrient levels, increased agricultural productivity, and decreased productivity levels of soil organic matter. Thus, proper fertilization management can circumvent the limiting factors such as the foliar application of boron and soil fertilization of zinc, both resulting in greater stem production. Molybdenum increases biological nitrogen fixation in sugarcane and contributes to the accumulation of N in the plant. Iron and manganese are involved in chlorophyll content and dry matter accumulation in sugarcane. In this review, we show the contributions of fertilization with microelements to the development of the sugarcane sector. In this perspective, more research is needed on micronutrient fertilization to increase sugarcane productivity in different soil and climate conditions.
BREAKING SEED DORMANCY IN Sesbania punicea (Cav.) Benth
Authors: Grzeça Gislaine Taís , Winhelmann Mara Cíntia , Emer Aquélis Armiliato , Tedesco Marília , Lazarotto Marília , Schafer Gilmar
Published: November 2022

The objective of this study was to evaluate methods of breaking dormancy in Sesbania punicea seeds for seedling production. The treatments used were control, manual scarification for 40 s, manual scarification for 60 s, thermal scarification and chemical scarification. After the treatments were carried out, the seeds were placed to germinate at 25 ºC and a 16-hour photoperiod for 14 days. The germination percentage, average germination time, germination speed index, percentage of normal seedling formation, shoot length, root system length and percentage of hard seeds were evaluated. A completely randomized design with four replications of 25 seeds was used. The data were submitted to ANOVA and the means compared by Tukey 5%. There was a difference for all the analyzes evaluated, except for the length of the aerial part. The treatment with manual scarification 60 s had superior results, being indicated for overcoming dormancy of seeds of S. punicea.
Physicochemical analysis of Brazilian spinach grown under doses of urea
Authors: Balbino Ferreira Almecina , Santos da Cruz Karine , Matos do Nascimento Matheus , Santos de Lima Marilene , Souza Torres Natalia , Carnaúba de Aragão Junior Antônio
Published: November 2022

The Althernanthera sessilis L. is a non-conventional food plant (PANC) popularly known as Brazilian spinach, rich in minerals and proteins, contributing to human nutrition. In view of the above, the present work aimed to analyze physicochemically Brazilian spinach plants cultivated under doses of nitrogen, in the form of urea. The experiment was carried out at the Experimental Garden of the Universidade Federal do Acre (UFAC), from November 25, 2017 to February 3, 2018 and the laboratory analyzes were carried out at the Unidade de Tecnologia de Alimentos (UTAL/UFAC). The delimitation used was completely randomized, containing 4 treatments (0; 1.5; 3.0 and 5.0 g), five replications and one plant per replication. The vegetative material was obtained in Porto Velho (RO) and the seedlings obtained by cuttings were cultivated in 500 mL polyethylene cups for 15 days and then transferred to pots with a capacity of 9 L. On February 3, leaves and stems of the plant were collected and analyzes were performed on a wet basis, except ash, such as pH, titratable acidity, ascorbic acid, soluble solids and proteins. Significant differences were observed for pH, titratable acidity, ascorbic acid and proteins and a linear increase of the contents with the increase of the urea dose. Nitrogen fertilization up to a dose of 5 g was efficient for the variables of titratable acidity, proteins and ascorbic acid. The highest dose of urea provided an increase of about 24% in protein content, however, even without fertilization, Brazilian spinach showed great potential in terms of protein content, being able to be consumed to supply part of the protein demand.
Agriculture performance of table cassava cultivars in west region of Pará
Authors: Bizerra Barros Ianna , Maia de Sousa Arlem Dalvany , Alves de Sousa Mateus , Camacho Palomino Edwin
Published: November 2022

The cassava crops have a great diversity of cultivars, mostly creole, being necessary studies that aim the selection of materials able to express its productive potencial in distinctive areas of Brazil. Thus, this work aimed to assess the agronomic characteristics and the productive of seven cultivars of table cassava, in the West region of Pará. The experiment was carried out in a rural property, in the municipality of Mojuí dos Campos (Pará). The experimental design was randomized blocks, with three repetitions. The treatments were constituted of local cassava cultivars (Água Morna, Roxa do Curudi, Amarelona, Olhinho, Máximo, Tabocal II e Paço Branco). The evaluated characteristics were: height of plants – HP (m), height of the first ramification – HR (m), diameter of the plant stem – DPS (cm), number of sprouts - NS, number of harvested roots - NHR, root fresh biomass – RFB (g), root dry biomass – RDB (g), diameter of roots –DR (cm), length of roots – LR (cm) and productivity (PR). For the characters in the aerial part, the ‘Roxa do Curundi’ cultivar showed the highest HP and HR ‘Máximo e Paço Branco’ expressed the highest DPS and NS, respectively. The cassava cultivars studied distinguished as to the characteristics of agronomic interest for inclusion in plant breeding programs of the species in the western region of the state of Pará. Among the evaluated cultivars, ‘Paço Branco’ is recommended for agricultural improvement, as it presents desirable characteristics, such as higher productivity and smaller size.
Inoculation of growth-promoting bacteria in the lettuce crop
Authors: Ribeiro Machado Fabiana , Ribeiro Machado Fabio , Guimarães Vandeir Francisco , De Moraes Echer Márcia
Published: November 2022

Plant growth promoting bacteria (PGPB) are an alternative to increase the productivity of several crops, including lettuce. Several reports are found in the literature with the use of plant growth-promoting bacteria in lettuce cultivation, but most seek increments during the production of seedlings. Aiming to provide increments in the cultivation of lettuce in the field and to generate subsidies to technicians and producers, the present work aimed to study the influence of the application of commercial products based on Azospirillum brasilense, Bacillus subtilis + B. megaterium and Pseudomonas fluorescens, on agronomic characteristics and quality of crisp lettuce. The experiment was implemented in two locations, in a randomized block design, in a 4 x 3 factorial scheme, with four replications. The first factor refers to the application of different PGPB: control, without inoculation; inoculations with A. brasilense; B. subtilis + B. megaterium and P. fluorescens. The second factor was composed of three times of application of PGPB, the first being on the day of seedling transplantation (DAT), the second at 15 STR and the third on the day of seedling transplantation + 15 DAT. At 15 DAT, the relative chlorophyll content, plant height, head diameter, number of leaves per plant, leaf area, leaf dry mass, stem dry mass, root dry mass, total dry mass, root volume were evaluated. and root length. At harvest, the same variables analyzed at 15 DAT + leaf fresh mass, stem fresh mass, head fresh mass, root fresh mass, total fresh mass and leaf contents of nitrogen, phosphorus and potassium were analyzed. The inoculated plant growth-promoting bacteria did not promote a significant increase in the development of the lettuce cultivar Vera when compared to the control (without PGPB application).
Tree component analysis in a savanna-forest ecotone area of Minas Gerais state, Brazil
Authors: Dias Cabacinha Christian , Guimarães Pereira Kelly Marianne , Gomes Cordeiro Natielle , Santos Fonseca Rúbia , Araújo Júnior Carlos Alberto
Published: November 2022

Ecotones are transition areas characterized by environmental complexity and high biodiversity. In this sense, carrying out a floristic survey and characterization of each phytoecological region is necessary. Thus, we analyzed the floristic composition, horizontal and vertical structure, and dispersal syndromes of the woody community in an ecotone of cerrado sensu stricto and seasonal deciduous forest. Likewise, we proceeded with the floristic similarity analysis to evaluate the study area’s similarities to the vegetation of cerrado sensu stricto and seasonal deciduous forest. A total of 919 individuals from 19 families, 43 genera, and 49 species were sampled. The tree community has an average height of 4.12 m, a species diversity of 3.03 nats.ind-1, and a Pielou equitability index of 0.77. The predominant dispersion syndrome was anemochory. The vegetation formed floristic groups with the cerrado sensu stricto. The environmental gradient that determines the occurrence of transition vegetation makes each remnant unique in terms of species and structure, demonstrating the importance of these areas for the biodiversity conservation.