bluuebunny/crossref_metadata_2025 huggingface dataset:
DESIGNING MARKETING ACTIVITIES OF BUSINESS STRUCTURES IN THE SERVICE SECTOR IN CONDITIONS COVID-19
Authors: Gontareva Iryna , Boyko Anastasia
Published: August 2022

COVID-19 encourages companies to quickly change their approaches to marketing activities and the competitiveness of various systems. Entrepreneurial structures face a number of new systemic priorities and challenges - the risks of disruption of business continuity, sudden quantitative changes in supply and demand, real-time decision-making, reduced productivity, threats to physical security.

The purpose of the study is to highlight the features of the design of marketing activities of enterprises in the field of medical services in a pandemic COVID-19.

It is substantiated that the peculiarities of marketing activities of enterprises in the field of medical services in the context of the COVID-19 pandemic are: a highly dynamic market; high speed of capital turnover, given the short productive cycle of the service itself; high sensitivity to changes in market conditions; specific provision of services; enterprises have high mobility; diversification, personalization and individualization of services.

The main areas of distribution of medical services, the relevance of which has increased in connection with the adoption of measures in response to the pandemic COVID-19 include: virtual medical services; analytics as a powerful tool for improving health and the economy; stability of supply chains; important technology-based innovations in clinical trials.

Virtual medicine holds great promise for patients with limited mobility or accessibility issues, but it can create additional inequalities or exacerbate current inequalities if vulnerable populations lack mobile devices, the connectivity and digital literacy to access these services. Healthcare enterprises should consider the possibility of access to technologies for vulnerable segments of the population when designing their strategies and focus more on ensuring cybersecurity, take into account the requirements of legislation on the protection of personal data and provide for effective protection systems in the developed solutions and products.
BANKING RISKS IN UKRAINE AND METHODS OF THEIR PREVENTION
Authors: Doroshenko Nadiya , Kulyk Nataliia , Pohorelenko Anastasiia
Published: August 2022

The banking system of Ukraine is the main component of the financial market, the proper functioning of each element of the banking system has a positive impact on the development of the economy as a whole. In today’s difficult conditions, the instability of global and national financial markets, the problem of ensuring financial adaptability and stability of banks is of great importance. Unfortunately, the activity of banks is impossible without risks. Compared to other types of business activities, the banking sector is characterized by the highest level of risk, which is due to the specifics of banking operations.

In recent years, Ukraine’s banking system has reached a stage of "cleansing". The political and economic crisis, which began in late 2013, worsened the financial condition of domestic banks. Both individual banks and the entire banking system of Ukraine today operate in difficult conditions with high risks. Banking is negatively affected by the low level of the resource base, the predominance of short liabilities, low incomes, and the shadow sector of the economy. Due to the unsatisfactory condition of borrowers, the banking system requires the creation of reserves, which in the absence of relatively stable sources of resources makes it difficult to form the resource base of commercial banks.

Despite the large number of works of scientists, in our opinion, the problem of improving methods of preventing banking risks remains insufficiently disclosed, which is why the chosen topic is relevant and needs further research.

Therefore, one of the most important tasks facing any bank in the world is to identify, assess, monitor, control and manage the bank’s risks. Such tasks should be solved by the banking system of Ukraine for the strategic development of the country and the improvement of all sectors of the economy.
UPAYA PENGENDALIAN DAN PENCEGAHAN COVID-19 DENGAN PEMBERDAYAAN KADER POSYANDU BALITA MELALUI EDUKASI PROTOKOL KESEHATAN DI KELURAHAN NGILIR KABUPATEN KENDAL
Authors: Ruspita Mimi , Rosiana Heny
Published: August 2022

Pandemi COVID-19 merupakan kondisi darurat global yang terjadi karena infeksi COVID-19 di seluruh dunia. Di Indonesia, dua bulan pasca kasus pertama COVID-19 terkonfirmasi, telah terkonfirmasi sebanyak 18.010 pasien positif COVID-19 dan sejumlah 1.191 meninggal. Untuk itu perlu penerapan protokol kesehatan untuk mencegah terjadinya penularan COVID-19 termasuk di Posyandu, padahal posyandu cenderung menimbulkan kerumunan mengingat sasaran bayi dan balita banyak, sehingga kader posyandu perlu dibekali strategi khusus untuk menerapkan protokol kesehatan.. Tujuan Pengabdian Masyarakat ini meningkatkan pengetahuan kader tentang protokol kesehatan serta mendorong partisipasi aktif kader mengedukasi ibu-ibu yang memiliki balita untuk menerapkan di Posyandu. Metode pengabdian yang dilakukan adalah dengan pendekatan penyuluhan tentang protocol kesehatan, serta pendampingan penerapan protokol kesehatan di Posyandu. Jumlah responden sebanyak 25 kader posyandu di Kelurahan Ngilir Kecamatan Kendal Kabupaten Kendal. Hasil pengabdian masyarakat ini menunjukkan adanya peningkatan pengetahuan kader tentang protokol kesehatan dengan rata-rata pengetahuannya 68,4 meningkat menjadi 83,2. Sedangkan hasil evaluasi penerapan protokol kesehatan ada 40% kader belum rutin mencuci tangan tiap 1 pelayanan dan 32% kader belum menjaga jarak. Kesimpulannya penyuluhan dapat meningkatkan pengetahuan kader tentang protocol kesehatan, namun dalam penerapannya masih ada yang belum rutin cuci tangan setiap satu kali pelayanan dan menjaga jarak
PENERAPAN APLIKASI HEXAGON TIGA DIMENSI PADA BUSANA PESTA MALAM
Authors: Lestari Astri Sri , Kharnolis Ec. Mein
Published: August 2022

Sumber ide yang di ambil terinspirasi dari cyber security, dan munculah ide penerapan aplikasi hexagon tiga dimensi yang berbuat dari tekstil kulit sintesis, yang mana inspirasi tersebut dari pancaran cahaya cyber security yang muncul secara bertabrakan sehingga cahaya tersebut memiliki bentuk menyerupai hexagon tampak timbul dan nyata. Tujuan penulisan ini untuk mengetahui proses pembuatan dan penerapan teknik aplikasi hexagon tiga dimensi pada busana pesta malam serta mengetahui hasil jadi pada pembuatan busana berdasarkan sumber ide. Proses pembuatan aplikasi tiga dimensi meliputi dari mempersiapkan mannequin sebagai alat cetak pada bagian bahu, membentuk kain flannel sesuai dengan ukuran bahu, mengukur dan memotong kertas duplek sesuai dengan tinggi, rendah, besar, dan kecil ukuran hexagon, memasang duplek yang telah di potong, dan merekatkan tekstil sintetis dengan lem tembak sebagai cover bangun tersebut. Penerapan aplikasi hexagon tiga dimensi pada busana pesta dimulai dari mempersiapkan aplikasi hexagon tiga dimensi yang telah di buat, mempersiapkan velcro  ukuran 3 cm, mengukur panjang dan pendek velcro yang akan digunakan, menyemat velcro dengan jarum pentul pada bagian bahu sebagai penguat perekat velcro, menjahit velcro dengan jarum tangan sebagai penguat tumpuhan. Hasil jadi busana yang menerapkan aplikasi hexagon tiga dimensi pada busana pesta terlihat indah, unik, futuristic dan elegant.

The source of ideas taken was inspiring by cyber security, and the idea of ​​applying a three-dimensional hexagon application that made from synthetic leather textiles, which was inspired by the collapsing cyber security light that appeared in a collision so that the light has a shape that resembles a hexagon seemed to arise and be real. The purpose of this paper is to determine the manufacturing process and application of three-dimensional hexagon application techniques in evening party outfits and to find out the finished results on fashion making based on the source of ideas. The process of making three-dimensional applications includes preparing mannequin as a printing tool on the shoulder, forming a flannel fabric according to shoulder size, measuring and cutting duplex paper in accordance with high, low, large, and small hexagon sizes, installing duplexes that have been cut, and glue synthetic textiles with firing glue as a cover. The application of three-dimensional hexagon in a party dress starts from preparing the three-dimensional hexagon application that has been made, preparing velcro size 3 cm, measuring the length and short velcro to be used, embedding velcro with a pin on the shoulder as a reinforcement for velcro adhesive, sewing velcro with hand needles as reinforcement. The results become fashion that applies a three-dimensional hexagon application to a party outfit that looks beautiful, unique, futuristic and elegant.
Some aspects of organizing the protection of fish from going into water intake facilities
Authors:   Timirâzevskaâ selʹskohozâjstvennaâ akademiâ, CHERNYKH O. N.
Published: August 2022

The results of laboratory studies of water intake structures of engineering-ecological type with devices that prevent fi sh from entering the water intake windows are presented. When they work in the water intake zone, optimal hydraulic conditions are created that contribute to the guaranteed fish diversion. Three versions of the protective device were studied: single heads of cylindrical and bull types, as well as a structure with a series of fi ve bull-type heads installed obliquely in the direction of the flow. Studies of the influence of the hydraulic structure and hydrodynamic characteristics of the fl ow on the entry of fish into the water intake were carried out in a mirror tray with a change in the water intake in the range of 17…52 l/s. The experiments involved juveniles of different breeds with a size of 35…45 mm. The kinematics turned out to be partly expected: with an increase in water withdrawal, the degree of flow concentration increased. Experiments have shown that when installing a series of water intake heads, the possibility of fish getting into the zone of water intake windows increases compared with the installation of single heads. When placing single heads, the maximum negative velocities in the zone of the water intake window and the distance at which they are observed behind the bull head are signifi cantly higher. As a result of the analysis of hydro biological studies, it was found that the capaability of fish to leave the zone of influence of water intake decreases sharply with an increase in the amount of water withdrawal (outcome III). With a single cylindrical head, the intensity of pressure pulsation is approximately by 18% greater than with a bull head. A series of water intake heads arranged obliquely in a checkered order has higher fish protection properties.
Al 6061/B4C/GNP hibrit kompozitlerde B4C ve GNP takviye miktarlarının abrasif aşınma davranışına etkisi
Authors: PUL Muharrem
Published: August 2022

Bu deneysel çalışmada aşınma davranışlarının incelemek amacıyla, vorteks yöntemi kullanılarak Al 6061 matrisli B4C ve GNP takviyeli hibrit kompozitler üretilmiştir. Daha sonra pin-on disk yöntemiyle, aşındırıcı zımpara kullanılarak abrasif aşınma deneyleri gerçekleştirilmiştir. Deney sonuçlarına göre, yapı içerisindeki B4C kompozit numunelerin sertlik değerlerini ve aşınma dayanımları yükselmiştir. GNP oranının artmasıyla, sertlik değerleri ve aşınma kayıplarında azalma meydana gelmiştir. Bu durum grafenin kuru yağlayıcı özelliği ile ilişkilendirilmiştir. Ayrıca kompozit yapı içerisindeki takviye topaklanmasına bağlı olarak oluşan porozitenin mekanik özellikler üzerinde olumsuz yönde etki yaptığı değerlendirilmiştir. Ayrıca, deneyler sırasında kompozit yapı içerisinden kopan B4C parçacıklarının, zımparayla birlikte ikinci bir aşındırıcı gibi davranarak, aşınma kayıplarının artmasında etkili olduğu değerlendirilmiştir.
Blended learning model based on portfolio and HOTS: How is it developed in LPTKs?
Authors: Herianto Edy , Dahlan Dahlan , Tripayana I Nengah Agus , Basariah Basariah , Setyowati Rr. Nanik
Published: August 2022

During the covid-19 pandemic, learning can no longer be done directly. LPTKs are given the option to organize blended learning, a mixture of offline and online. The main problem is how to develop blended learning, which includes portfolio focus and HOTS? This is development research. The aim is to find, develop and validate a product produced during 2020/2021, even the semester lecture process. The resulting learning products can be in the form of lecture handouts, final assignments, and lecture textbooks resulting from the application of portfolio-based and HOTS-based blended learning models. The process to be carried out in the development of learning products includes 1) planning (preliminary studies, proposal making), 2) product development, 3) product trials and revisions, and 4) dissemination and utilization. The results of the discussion on the acquisition of existing data can be concluded that the blended, portfolio, and HOTS-based learning activities have been carried out smoothly and comprehensively. The implementation of blended learning can be seen in the discussion of online and offline lectures and offline lecture exams. The student activity portfolio is contained in lecture activities, individual and group assignments, and individual exams. HOTS content is contained in assignments individually and in groups.
Customer relationship management strategy in Starbucks card optimization in the Pandemic era
Authors: Munifa Hartoyo
Published: August 2022

Marketing communication is important, in this case paying attention to Customer Relationship Management. The number of companies that are currently competing fiercely has become a trigger for Starbucks Indonesia to maintain the loyalty of existing customers because the competition is quite tight from competitors considering that this company is engaged in the food and beverage sector which means maximum service and quality of products delivered to customers. In this era of pandemic, Starbucks ' card strategy is very profitable and makes it easier for customers to order drinks or food online. The existence of loyal customers is evidenced by the use of the Starbucks Card, so the purpose of this study is to determine the Customer Relationship Management Strategy in Optimizing the Starbucks Card in the Pandemic Era. This study used a qualitative approach and data collection techniques were carried out through interviews and document studies. For data collection techniques, the authors conduct interviews and view related documents which later the information obtained will be equated with the theory that the author uses in this study, namely Customer Relationship Management Theory and Loyalty Theory.
The Change Of Political Power From May 14, 1950 Parliamentary Elections to May 22, 1950 Presidential Elections
Authors: GÖKÇELER Onur
Published: August 2022

Türkiye’de çok partili hayatın başlaması sonucunda kurulan Demokrat Parti, 1946 seçimleri sonucunda Mecliste temsil edilmeye başlamıştır. DP’nin Meclisteki ilk zamanları, daha önce bu tür bir muhalefete alışık olmayan Cumhuriyet Halk Partisi yöneticilerinin de duruma alışma sürecinde zorluklarla geçmiştir. Ancak CHP Genel Başkanı ve Cumhurbaşkanı İsmet İnönü’nün muhalefeti koruyan yönetim anlayışı çok partili hayatın devam etmesinde önemli derecede etkili olmuştur. 14 Mayıs 1950’de yapılan seçimler ile DP seçimleri kazanmış, CHP’nin tek parti iktidarı son bulmuştur. 22 Mayıs 1950’de yapılan cumhurbaşkanı seçimine kadar geçen bir haftayı aşkın sürede, iktidar değişimi hazırlıkları yapılmıştır. İnönü, seçimlerin kaybedildiği anlaşılınca hemen DP Genel Başkanı Celal Bayar’ı çağırarak iktidarı kendilerine bırakmaya hazır olduklarını söylemiştir. Bu durum kamuoyuna da açıklanarak çıkabilecek tüm söylentilere erkenden engel olunmuştur. Böylece CHP’nin iktidarı devretme, DP’nin de devralma hazırlıkları yapılmıştır. CHP muhalefete hazırlık yaparken, DP de yeni yönetici kadroyu belirleyerek iktidara hazırlık yapmıştır. 22 Mayıs’ta Bayar’ın cumhurbaşkanı seçilmesiyle iktidar değişimi resmen gerçekleşmiştir. Bu çalışma, iktidarın değişim hazırlığının nasıl yapıldığını dönemin ulusal gazetelerini ve siyasetçilerin anılarını ve günlüklerini içerik ve söylem analizi ile irdeleyerek ortaya koymaktadır.
SAFE MANAGEMENT OF E-WASTE DISPOSAL TO PREVENT HARMFUL EFFECTS ON HUMAN HEALTH AND THE ENVIRONMENT
Authors: Yuliana Yuliana
Published: August 2022

Using electronic devices is a common thing nowadays. Moreover, in the COVID-19 pandemic, all activities must be done from home. Learning, working, and leisure activities are done from home by gadgets. Therefore, electronic device demands are getting higher. E-waste disposal must be a concern for all electronic device users. Lack of awareness on proper management for e-waste disposal may cause harmful effects on human health, plants, soils, and the environment. The effects are increasing the risks of cancers, soil, and environmental pollution. This paper aims to describe the safe management of e-commerce-waste disposal to prevent harmful effects on human health and the environment. Databases from Science Direct, PubMed, and Google Scholar were used. The keywords were disposal AND environment AND e-waste AND health AND management. There were 2170 journals at the beginning. After screening by the title, abstract, and full text, there were 35 journals. Inclusion criteria were full text available, review, and research. Exclusion criteria are opinion and commentary. Reverse logistics is a way to dispose of e-waste by increasing the economic value of the waste. Another alternative to e-waste management is making art and craft from e-waste. Conclusion: Reverse logistics must be taught to people to save the planet from the harmful effects of the unwise management of e-waste disposal. Art and craft from e-waste can be done to increase economic value and reduce hazards to health and the environment. Soil assessment of heavy metal concentration surrounding the waste dump area must be done regularly to prevent bioaccumulation.
Effect of Adding Different Levels of Duckweed (Lemna minor Linn.) in the Diet on Live Body Weight, Hematological Traits and Production Cost of Free-range Chickens, Gallus domesticus Linn. (Black Austrolorp x Barred Playmouth Rock)
Authors: Paguia Hermogenes M. , Paguia Rina Q. , Pinsel Jesus Rex A. , Zaballa Steve , Abuan Abigail G. , Corpuz Mark Nell Castillo
Published: August 2022

The present study was conducted at Bataan Peninsula State University Abucay Campus to evaluate the growth performance and hematological profile of Gallus domesticus Linn. (Black Austrolorp x Barred Playmouth Rock) chicken fed formulated diets of varying inclusions of lesser duckweed (Lemna minor Linn.). Three formulated treatments diets of homogenous crude protein level were prepared: 0% duckweed (control), 10% duckweed, and 15% duckweed inclusion. Five chickens (average weight 202.5 g) per replicate were reared in a single factorial experiment and the feeding trial was carried-out for three months. Chicken fed diet containing 15% duckweed meal treatment had significantly (P < 0.05) higher body weight (1,425.88 ± 55.24 g) compared to chicken fed normal diet (1,223.48 ± 174.47 g). Mean cost to produce a kilogram of meat was significantly cheaper in the treated diets (F = 4.82; P < 0.05). Mean values of hematological variables were not significantly different among treatments.
Rekonstruksi Strategi Misi Gereja di Era Revolusi Industri 4.0
Authors: Aliano Yohanes Alfrid , Riyanto Eko Armada
Published: August 2022

Abstract. The authors place the focus of this study on the reconstruction of the strategy of the Church's missionary work by involving the active role of Catholics in the era of the industrial revolution 4.0. The so fast changing times require the Church to be able to see, interpret, evaluate and strengthen the basis of the Church's mission in the light of the faith, hope and love of Jesus Christ by involving all Catholic people. The method used in this study is a literature study in the perspective of Pope Benedict XVI's messages. Through this study, it is understood that in the midst of this sophisticated and modern industrial era, the missionary work of the Church must still place love as the basis of its mission, while at the same time following the currents of modernity. The mission of the Church is a call to work for all believers to fulfill the Great Commission of Jesus Christ.Abstrak. Penulis meletakkan fokus studi ini pada rekonstruksi strategi karya misi Gereja dengan melibatkan peran aktif umat Katolik di era revolusi industri 4.0. Perubahan zaman yang begitu cepat menuntut Gereja untuk mampu melihat, memaknai, mengevaluasi serta memperkokoh dasar karya misi Gereja dalam terang iman, harapan dan kasih Yesus Kristus dengan melibatkan seluruh umat. Metode yang digunakan dalam kajian ini adalah studi pustaka dalam perspektif pesan-pesan Paus Benediktus XVI. Melalui kajian ini diperoleh pemahaman bahwa di tengah era industri yang canggih dan modern ini, karya misi Gereja harus tetap menempatkan kasih sebagai dasar misinya, dengan sekaligus mengikuti arus modernitas. Misi Gereja adalah merupakan panggilan untuk berkarya bagi seluruh umat dalam rangka memenuhi Amanat Agung Yesus Kristus.
THAILAND'S HEDGING STRATEGY IN THE US-CHINA COMPETITION
Authors: KEYVAN Özlem Zerrin
Published: August 2022

Since the end of the Cold War, The US and Thailand have seemed headed for a more strained and distant relationship. For this reason, China has become more interested in deepening cooperation. Following the 2006 and 2014 military coups, the US government has decided to cut military aid to Thailand and publicly criticized the military regimes. China has not deviated markedly from its traditional foreign policy approach towards Thailand. Under the leadership of military regimes, the country adopts hedging strategies in order to maintain domestic stability, to promote inclusive economic growth, to maneuver through the changing geopolitical environment around its peripheries, and to keep more support for pro-China and pro-U.S orientation. This article addresses the US- China rivalry from the hedging strategy of Thailand , as opposed to the concept of more traditional balancing and bandwagoning. It examines why and how, despite the tensions of the US- China rivalry, Thailand has pursued a hedging strategy towards China.
Study of regional indicators of preferential medication provi-sion for persons who have had acute cardiovascular diseases (CVDs), on the example of the Tyumen region
Authors: Firsenko N.P. , Bredneva N.D. , Putintseva A.S. , Chikarenko E.I. , Sharsina E.A.
Published: August 2022

Goal. To study the indicators characterizing the program of preferential medication provision in the Tyumen region for persons suffering from acute cardiovascular diseases for the period 2020-2022. In particular, the structure and amount of funds from the budgets of all levels allocated for the provision of medication care to this category of patients, the number of citizens included in the regional Register of persons who have had acute cardiovascular diseases, the number of provided prescriptions for preferential medication provision, their average cost. To identify the main trends in the development of a new strand in the preferential provision of medicines for patients of medical organizations in the Tyumen region. Materials and methods. In the study of indicators, methods were used: situational-logical, content analysis, structural, system, computer technologies. Results. The organization of a new strand of preferential medication provision for people who have suffered acute cerebrovascular accident, myocardial infarction and other diseases has been studied. An analysis of the regulatory and legal regulation of preferential medication provision, indicators affecting the availability of medication care to patients of medical organizations based on monitoring stocks of medicines, their receiving by pharmacies, prescribing and dispensing necessary medicines was carried out. Conclusion. The Program of preferential provision of necessary medicines is being implemented at the expense of the federal (27%) and regional (73%) budgets in Tyumen region for providing primary health care to the patients who have suffered acute cardiovascular diseases. Indicators of medicine provision (program funding, number of prescriptions provided, average prescription cost) are dynamic, tend to grow and indicate the availability of medication care.
A Content Analysis of English Curriculum Evaluation Studies in Turkey (Between 2005-2021)
Authors: SÜER Sedef
Published: August 2022

Updating and evaluating language teaching programs in Turkey is an important issue, which lead to this issue occupies an important place in the scientific field. This study aimed to examine and determine the research trends in the postgraduate theses conducted to evaluate the English teaching programs prepared and updated by the Ministry of National Education since the year of 2005. The study was based on the document analysis design and included a total of 52 theses aiming to evaluate English teaching programs between 2005 and 2021 years. The findings showed that the majority of the postgraduate studies aiming to evaluate English language teaching programs were carried out in the last five years, and targeted to evaluate 2012-2013 teaching programs especially designed for early age groups (such as 2nd, 4th and 5th grades). Although Eisner’s Educational Connoisseurship model is the most preferred curriculum evaluation model in graduate theses, a great number of theses were based on the elements and the effectiveness of the curriculum in practice. The theses were determined to adopt mixed methods and descriptive survey design while teachers were preferred as the data source and the studies were carried out with a sample size of 1-50 people without using sampling method. The data of the study in postgraduate theses were collected mostly with survey and interview, and were analyzed with descriptive statistics and comparison tests. With this study, the general tendency or framework of studies evaluating language teaching programs, one of the most preferred areas for curriculum evaluation studies, was revealed.
Pengembangan Buku Ajar Berbasis Model Problem Based Learning pada Subtema 1 Kekayaan Sumber Energi Di Indonesia pada kelas IV Sekolah Dasar
Authors: Aprilia Widia , Apreasta Lika , Prasetyo Dian Estu
Published: August 2022

Berdasarkan latar belakang peneliti, materi dibuku siswa kurang lengkap, penyajian soal yang tidak sesuai dengan materi dibuku siswa dan guru hanya menggunakan buku guru. Upaya untuk mengatasi permasalahan tersebut, diperlukan Pengembangan buku ajar berbasis model Problem Based Learning (PBL) bertujuan untuk menghasilkan buku ajar berbasis model PBL untuk guru dan peserta didik kelas IV SD yang valid, praktis, dan efektif. Model Pengembangan 4D yang terdiri dari beberapa tahap yaitu: Tahap pendefinisian meliputi analisis kurikulum, analisis karakteristik peserta didik, analisis materi dan merumuskan tujuan. Tahap perancangan dilakukan merancang lembar instrumen dan buku ajar berbasis model PBL. Tahap pengembangan, rancangan buku ajar diubah bentuk wujud nyata produk dan tahap penyebaran buku ajar ini sangat terbatas. Hasil penelitian pengembangan buku ajar menggunakan uji validitas diperoleh data persentase RPP 89% dengan kategori sangat valid. Hasil persentase buku ajar diperoleh 84% dengan kategori sangat valid. Hasil uji praktikalitas dari Penilaian respon guru diperoleh 92% dengan kategori sangat praktis. Sedangkan hasil uji efektifitas yang didukung oleh penilaian hasil belajar dengan hasil persentase 84% dengan kategori sangat efektif. Pengembangan buku ajar berbasis model PBL pada subtema 1 kekayaan sumber energi di indonesia di kelas IV SD yang dikembangkan telah memenuhi minimal kriteria valid, praktis dan efektif.
Peningkatan Aktivitas Dan Hasil Belajar Biologi Materi Enzim dan Metabolisme Sel Menggunakan Model Pembelajaran Kooperatif Tipe Jigsaw Siswa Kelas XII Mia SMAN 1 Tebing Tinggi Tahun Pelajaran 2021/2022
Authors: Hastuti Widi
Published: August 2022

Penelitian ini dilatarbelakangi oleh rendahnya aktivitas dan hasil belajar siswa kelas XII MIA SMA Negeri 1 Tebing Tinggi Tahun Pelajaran 2021/2022 pada mata pelajaran Biologi. Tujuan penelitian ini adalah untuk mengetahui apakah penggunaan model pembelajaran kooperatif tipe jigsaw dapat meningkatkan proses pembelajaran, aktivitas dan hasil belajar siswa. Penelitian tindakan kelas ini dilaksanakan dalam 2 siklus dan pada masing-masing siklus terdiri dari 2 kali pertemuan. Subjek penelitian tindakan kelas ini adalah siswa kelas kelas XII MIA  SMA Negeri 1 Tebing Tinggi Tahun Pelajaran 2021/2022  dengan jumlah siswa sebanyak 10 siswa terdiri dari laki-laki sebanyak 5 siswa dan perempuan sebanyak 5 siswa. Validasi data dalam penelitian ini menggunakan teknik triangulasi data Teknik pengumpulan data dengan menggunakan lembar observasi, teknik tes dan dokumentasi. Analisis data menggunakan teknik deskriptif kualitatif. Hasil analisis data menunjukkan bahwa penerapan model pembelajaran kooperatif Jigsaw terbukti dapat meningkatkan aktivitas belajar siswa. Hal  ini buktikan dari hasil penelitian yang menunjukkan peningkatan ketuntasan belajar pada setiap siklusnya, dimana pada kondisi awal hanya ada 3 siswa atau 30,00% meningkat menjadi 7 siswa atau 70,00% dan 10 siswa atau 100% pada siklus terakhir. Penjelasan peningkatan hasil dan ketuntasan belajar juga meningkat pada setiap siklusnya dari 59,00 menjadi 68,75 dan 74,00 pada siklus kedua.  Hal tersebut juga dibuktikan dengan peningkatan ketuntasan belajar secara klasikal dimana pada kondisi awal hanya terdapat 3 siswa atau 30,00% meningkat menjadi 60% atau 6 siswa dan 9 siswa atau 90,00% pada siklus kedua. Dari penjelasan di atas maka dapat disimpulkan bahwa penggunaan model pembelajaran kooperatif tipe jigsaw dapat meningkatkan aktivitas dan hasil belajar siswa kelas XII MIA  SMA Negeri 1 Tebing Tinggi Tahun Pelajaran 2021/2022.
Public-Sector Leadership and Philanthropy: The Case of Broad Superintendents
Authors: Dee Thomas S. , Loeb Susanna , Shi Ying
Published: August 2022

Philanthropic initiatives incorporating prescriptive practices have become prominent in K–12 education. This study provides evidence on the reach, character, and impact of the Broad Superintendents Academy, a controversial initiative designed to transform district leadership. A novel data set on Broad trainees linked to data on large districts over 20 years shows that Broad superintendents have had extensive reach, serving nearly 3 million students at their peak, and that, for districts that hired Broad trainees, Broad superintendents were 40% more likely to be Black than non-Broad superintendents, although they had significantly shorter tenures. Estimates provide evidence that Broad-trained leaders had little effect on several district outcomes including enrollment, spending, and student completion. However, they initiated a trend toward increased charter school enrollment.
cAMP Response Element-Binding Protein Controls the Appearance of Neuron-Like Traits in Chorion Mesenchymal Cells
Authors: Innamorati Giulio , Ridolfi Giovanni , Steccanella Federica , Bormetti Alice , Dallatana Alessia , Bozzetto Cristina , Ottoboni Linda , Di Chio Marzia , Giacomello Luca
Published: August 2022

Background: Mesenchymal stromal cells (MSC) from bone marrow have been reported to undergo the initial phases of neural differentiation in response to an increase of intracellular cAMP. We investigated the possibility that a similar effect applies to chorion-derived MSC. Methods: The intracellular concentration of cAMP was increased either by forskolin, to promote its synthesis, or by inhibitors of its degradation. The consequent reduction in the expression of mesenchymal markers was associated with the appearance of neuron-like morphology in a subset of cells. The effect was measured and characterized using biomarkers and an inhibitor of cAMP response element-binding protein (CREB). Results: The dramatic morphological change induced by all the treatments that promoted intracellular cAMP was transient and peaked on the third day. After that, cells returned to the typical fibroblast-like appearance within 24 hours. The distinctive morphology was associated to the expression of neuregulin 1, doublecortin, neuron-specific class III β-tubulin, and required cAMP response element-binding protein activity. Basic-fibroblast growth factor (b-FGF) treatment increased both the timeframe and number of cells undergoing the morphological change induced by the effect of forskolin. As opposite, arginine-vasopressin (AVP) and sphingosine-1-phosphate (S1P) reduced it. Conclusions: We conclude that cAMP and the ensuing CREB activation trigger a preliminary step towards neuronal differentiation of chorion-derived MSC. However, likewise other MSC, the stimulus is not sufficient to promote stable differentiation.
Gui Shao Tea Extracts Inhibit Gastric Cancer Growth in Vitro and in Vivo and Prolong Survival in Nude Mice
Authors: Liu Yue , Jiang Zhouyue , Yang Hongwei , Yuan Jingyi , Zeng Jiali , Wu Jiayan , Xu Zhijian
Published: August 2022

Background: Gui Shao Tea (GST), a long-aged tea with a Chinese herbal aroma, can treat many stubborn and malignant diseases, according to traditional Chinese medicine. This research aimed to discover and define GST, study the anti-gastric cancer effects of GST extracts and preliminarily elucidate the mechanism of action in the PI3K/Akt signaling pathway and the gut microbiota. Methods: GST was analyzed by GC/MS and HPLC. Cell proliferation, the cell cycle and apoptosis were evaluated by a CCK8 assay and flow cytometry. The effects of GST extracts on tumor inhibition and survival time were explored by a gastric cancer xenograft model in nude mice. The PI3K/Akt signaling pathway was assessed by western blotting and immunohistochemistry. Gut microbiota detection and fecal microbiota transplantation were performed to examine whether the tumor inhibition observed in mice was related to gut microbiota changes. Results: The ingredients in GST, mostly terpenes and their derivatives, were novel and more concentrated than those in tea made from the branches and leaves of the same plant species, Camellia sinensis, picked and produced the same year, while the levels of polyphenols and alkaloids were significantly reduced. In BGC-823, MGC-803, and SGC-7901 gastric cancer cells, GST extracts significantly inhibited proliferation (p = 0.037), induced G0/G1 arrest (p < 0.001) and promoted early apoptosis (p = 0.041). In mice, gastric tumor growth was significantly inhibited in both the high-dose (HTF) and middle-dose (MTF) GST-fed groups. The inhibition rate in the HTF group was 33.77% on Day 14 (p = 0.042), and that in the MTF group was 55.21% on Day 14 (p = 0.002) and 61.6% on Day 28 (p = 0.008). The survival time of MTF group mice was significantly prolonged by 22.2% (p = 0.013). GST extracts inhibited the PI3K/AKT signaling pathway in gastric cancer cells (p = 0.016) and tissues (p = 0.029), downregulated the protein p-Rb and further downregulated E2F1, thereby affecting the cell cycle and proliferation. GST extracts altered the gut microbiota in mice, but these alterations alone were insufficient to inhibit gastric cancer growth. Conclusions: We confirmed the anti-gastric cancer effects of GST extracts, which might provide new approaches and methods for research and development of gastric cancer drugs.
Safer and Smarter: Leveraging Transfer Learning and Data Fusion of Disease and Environmental Data for Modeling Plant Disease Risk
Authors: Alves Kaique Santos , Shah Denis A. , Dillard Helene R. , Del Ponte Emerson Medeiros , Pethybridge Sarah J.
Published: August 2022

Plant disease epidemiologists may find themselves on the smaller end of the big data continuum, particularly with field data. Nevertheless, it is tempting to use data-hungry machine learning (ML) algorithms, lured by the promises of highly accurate predictions. We show that the mismatch between data size and algorithmic data requirements leads to overfitting, which can be mitigated by using the more complex ML algorithms in a transfer learning capacity, leveraging knowledge from a pre-trained model on one task to enhance learning on a related, smaller dataset or task. An observational dataset on white mold prevalence in snap beans in New York State was enhanced by fusing georeferenced observations with soil-related variables and features engineered from downscaled environmental data. First, functional data analysis was applied to identify key periods within the weather series that best discriminated disease prevalence. Second, random forests were used in an interpretive role to identify three variables most associated with white mold prevalence. Finally, these variables were transferred to a logistic regression framework to build a simpler predictive model. Random forests, while producing accurate predictions, exhibited signs of overfitting and poor calibration. The internally-validated logistic regression model by contrast possessed better calibration properties, an acceptable level of discrimination and practical utility according to decision curve analysis. Analytical workflows should be mindful of actual dataset size. With smaller datasets, our results suggest using ML as an interpretative tool to guide the development of simpler, less data-intensive predictive models better suited to dataset size.
Direct accessibility for overgeneral memory predicts a worse course of depression: Re-analysis of the online computerized Memory Specificity Training (c-MeST) for major depression study
Authors: Matsumoto Noboru , Hallford David John
Published: August 2022

Researchers have been interested in what retrieval process is responsible for overgeneral autobiographical memories (OGM) in depression. Previous cross-sectional studies demonstrated that, for negatively-valenced cues, directly retrieved OGM, rather than generatively retrieved OGM, are associated with depression. However, longitudinal evidence of this relationship is still lacking and needs to be tested. We conducted a re-analysis of the online computerized memory specificity training (c-MeST) data to examine whether directly retrieved OGM for negative cues prospectively predicts high levels of depression one month later. The results supported our prediction, and directly retrieved OGM for negative cues predicted higher later depressive symptoms even after controlling for baseline depressive symptoms, executive function and rumination. Exploratory analysis showed that direct retrieval of specific memories prospectively predicted low levels of depression. These results support the theory that elevated accessibility of negatively-valenced general memory representations are a vulnerability factor for depressive symptoms.
Factors related to low birth weight in Indonesia
Authors:   Faculty of Health Science, Muhammadiyah University of Jember, Jember, Indonesia, Rohmah Nikmatur , Masruroh Masruroh ,   Faculty of Health Science, Universitas Pesantren Tinggi Darul Ulum Jombang, East Java, Indonesia, Marasabesy Nur Baharia ,   Maluku Health Polytechnic, Ministry of Health, Ambon, Indonesia, Pakaya Nasrun ,   Faculty of Sport and Health, State University of Gorontalo, Gorontalo, Indonesia, Prasetyo Joko ,   Stikes Bahrul Ulum, Jombang, Indonesia, Walid Saiful ,   General Hospital of Dr. H. Koesnadi Bondowoso, Indonesia, Laksono Agung Dwi ,   The National Agency for Research and Innovation of The Republic of Indonesia, Jakarta, Indonesia
Published: August 2022

Introduction: Previous studies have reported that low birth weight (LBW) correlates with neonatal death and 15 - 20% of all births worldwide are LBW. This research aimed to analyse the factors related to LBW in Indonesia. Methods: The authors collated secondary data from the 2017 Indonesian Demographic and Health Survey (IDHS). The sample consisted of 17,443 respondents. Besides LBW as the dependent variable, the independent variables consisted of maternal age, residence, wealth, education, employment, marital status, health insurance, antenatal care (ANC) visits, smoking behaviour, and gender of the baby. The final stage employed binary logistic regression. Results: Women aged 35-39 years were 0.688 times less likely than women aged 15-19 years to give birth to LBW babies. The wealthiest women were 0.712 times less likely than the poorest women to give birth to LBW babies. Women with higher education levels were 0.670 times less likely to have a LBW baby than women with no education level. Women who attended ≥4 ANC visits were 0.829 times less likely to have LBW babies than women who attended <4 ANC visits. Baby girls were 1.161 times more likely than baby boys to be born with LBW. Conclusion: The study concluded that the factors related to LBW in Indonesia were maternal age, wealth, education, ANC, and gender of the baby.
Hepatoprotective activity of Amalakyadi Gana, a polyherbal ayurvedic formulation in paracetamol-induced hepatotoxicity in mice
Authors: Ray Shreyosi , Taraphdar Amit K. , Gupta Mradu
Published: August 2022

Since ancient times, Amalakyadi Gana, a polyherbal formulation of Susruta Samhita (6th century BCE), has been used for the prevention and treatment of numerous gastrointestinal diseases. This formulation consists of fruits of Phyllanthus emblica, Terminalia chebula, Piper longum, and the root of Plumbago zeylanica. The hepatoprotective efficacy of this formulation was evaluated following the acute toxicity study in mice to validate its ayurvedic uses. The hepatoprotective efficacy was assessed using paracetamol-induced hepatotoxicity in Swiss albino mice. Research drug exhibited in normalizing the PCM-dependent rise of serum liver function markers. After administration of the aqueous extract of Amalakyadi Gana, relevant blood biochemical measures showed significant (P < 0.05) hepatoprotective activity in a dosage-dependent manner, especially at the dose of 700 mg/kg orally in mice. When compared to the control group, significant (p < 0.05) histological alterations were also observed in the liver tissues. This formulation exhibited results in normalizing the liver architecture by decreasing necrotic foci along with the normal liver parenchymal structure in the research drug pre-treated groups mainly at the dose of 700 mg/kg, caused due to paracetamol toxicity. The research drug's sustained activity was comparable to that of the silymarin (200 mg/kg, p.o.) reference medicine. This formulation possesses significant hepatoprotective activity without any toxicity in mice.
Antimicrobial activity and brine shrimp toxicity of propolis collected from various regions of Tanzania
Authors: Ngassapa Olipa David , Runyoro Deborah Kiumlo Balira , Maregesi Sheila Mgole , Sangeda Raphael Zosimus , Msemo Stephen , Mwakalukwa Rogers , Kidukuli Abdul Waziri , Marandu Ezekiel
Published: August 2022

Background: Propolis has been traditionally used in many countries for management of various health conditions and many previous studies have shown that it has many biological activities, including antimicrobial activity and cytotoxicity. However, not much has been studied with regard to Tanzanian propolis; hence this study reports biological activity of propolis collected from 8 regions of Tanzania. Objectives: The purpose of this study was to evaluate the antimicrobial activity and potential cytotoxicity of propolis samples collected from various regions of Tanzania. Metet hods: Ethanolic extracts of 28 propolis samples collected from 8 regions in Tanzania were evaluated for antimicrobial activity against Gram +ve bacteria, Gram -ve bacteria and fungi, using the broth microdilution method, through which minimum inhibitory concentrations were determined. Brine shrimp lethality test was done using Artemia salina nauplii, as a preliminary indication of potential anticancer activity. Results: Out of 28 tested propolis samples, 21 exhibited antimicrobial activity on one or more microorganisms at the tested concentrations, with MICs of 1.25 – 5.0 mg/ml. Fourteen out of 28 samples were found to be toxic on brine shrimps, with a sample from Singida region being the most toxic. Conclusion: Propolis samples from various regions of Tanzania demonstrated antimicrobial activity on some microorganisms, indicating that they are a potential source of antimicrobial agents. Some samples also exhibited brine shrimp toxicity; implying that they may also be toxic on cancer cells and thus, may be a potential source of anticancer agents. They may also be a source of compounds with other biological activities.
A Pre-Registered Test of a Correlational Micro-PK Effect: Efforts to Learn from a Failure to Replicate
Authors: Maier Markus , Dechamps Moritz
Published: August 2022

Micro-psychokinesis (micro-PK) research studies the effects of observers’ conscious or unconscious intentions on random outcomes derived from true random sources such as quantum random number generators (QRNGs). The micro-PK study presented here was originally planned, preregistered, and conducted to exactly replicate a correlational finding between two within-subject experimental conditions found in an original micro-PK dataset (n = 12,254) using a QRNG. However, after data collection and analyses, a data error was detected in the original to-be-replicated dataset. A reanalysis of the original correlation effect after error correction revealed strong evidence for the absence of a correlation in the original data. This study’s primary goal was to test the existence of a correlational micro-PK effect in the present data as specified in the pre-registration. In addition to this replication attempt, the present study also can be considered an unsystematic case report or field study on experimenter psi (e-psi), since a strong expectation was formed initially about the occurrence of an effect that indeed was objectively absent from the original data. This study’s results indicate no evidence for the existence of a correlational (and standard) micro-PK effect. In other words, the actual correlational data did not meet the experimenters’ conscious expectations, and thus no consciously based effect of e-psi on micro-PK was found. However, the change in evidence for the effect across time described by the sequential Bayes factor resembled a data pattern that also was frequently reported by the experimenters in past studies. Although these data did not meet the criterion of statistical significance, the marginal effects might be interpreted as weak influences based on unconscious e-psi. In addition, the trend observed matches both experimenters’ general beliefs about the occurrence of e-psi in micro-PK. These findings’ implications for the application of scientific methods to the study of micro-PK and psi in general are discussed.
 
KEYWORDS
 
Experimenter effects, experimenter psi (e-psi), micro-psychokinesis (micro-PK), quantum random number generator (qRNG)