bluuebunny/crossref_metadata_2025 huggingface dataset:
Антимикотическое действие экстракта Lathyrus vernus subsp. Vernus в отношении биоплёнок дрожжеподобных грибов рода Candida. Сачивкина Н.П.
Authors:   Российский университет дружбы народов, Сачивкина Н.П.
Published: November 2023

Поиск новых средств для борьбы с возбудителями болезней продолжается, и растительные экстракты заслуживают внимания как перспективные средства борьбы с биопленками микроорганизмов. Они могут действовать, не разрушая микробные клетки, как это делают антибиотики, а избирательно изменяя их поведение, что достигается в первую очередь за счет взаимодействия с системой кворума. Этого бывает вполне достаточно для полного выздоровления без осложнений, поскольку не происходит хронизации инфекции из-за накопления клеток возбудителя в биопленках. Известно, что дрожжеподобные грибы рода Candida являются важной причиной многих грибковых инфекций человека и животных. Помимо Candida albicans в последние годы многие инфекции вызываются не-albicans видами, такими как C. parapsilosis, C. tropicalis, C. krusei, C. glabrata, C. guilliermondii и др [1]. Основные противогрибковые агенты относятся к трем разным классам, включая азолы, полиены и эхинокандины. Однако во всем мире наблюдается увеличение резистентности данных микроорганизмов ко всем трем категориям лекарств. Поэтому возникает острая необходимость в поиске других альтернативных средств с противогрибковой активностью. Многие экстракты трав и соединения из природных источников проявляют превосходную противогрибковую активность. Например, полученный нами экстракт, содержащий терпеноиды, в том числе и Фарнезол, из воздушно-высушенных побегов Чины весенней Lathyrus vernus subsp. Vernus в соотношении сырье:экстрагент - 1:10, с использованием в качестве экстрагента водно-спиртового раствора с концентрацией этанола 70-95% путем экстрагирования с обратным холодильником в течение 30 минут. Мы проводили линию опытов по биопленкообразованию с использованием 96-луночного стерильного полистиролового планшета, в лунки которого вносили исследуемые культуры: C. albicans, C. parapsilosis, C. tropicalis, C. krusei, C. glabrata, C. guilliermondii, и инкубировали 72 часа при 37°С. После культивирования лунки планшета трижды промывали фосфатным буфером и сушили в течение 15 минут. В каждую лунку добавляли 1% раствор кристаллического фиолетового. Затем снова промывали, сушили и добавляли по 150 мкл 96% этанола. Через 15 минут регистрировали результат на микропланшетном спектрофотометре при длине волны 492 нм [2, 3]. Было обнаружено, что фитоэкстакты подавляли рост биопленок разных видов кандид в среднем на 73%. Результаты исследования могут быть использованы для разработки новых антигрибковых препаратов, не вызывающих устойчивости, что позволит в перспективе применять эти препараты в качестве альтернативы традиционным антимикотикам или как дополнение к ним. Публикация выполнена при поддержке Программы стратегического академического лидерства РУДН.
Структура сосновых древостоев центральной части Кольского полуострова
Authors:   Российский государственный педагогический университет им А. И. Герцена, Евдокимов А.С.
Published: November 2023

Вследствие активной хозяйственной деятельности почти на всем протяжении ХХ века наиболее заселенные и промышленно развитые территории Мурманской области (центральная и восточная часть) сформированы средневозрастными лесами [3]. Наряду с влиянием рубок, ландшафты сильно преобразуются в результате сопутствующих лесных пожаров [1, 2]. Как итог, средний возраст древостоев (и, соответственно, сообществ в целом) составляет около 100 лет. Целью данной работы является анализ размерной структуры древостоев сосны обыкновенной (Pinus sylvestris L) в разных типах средневозрастных сосновых лесов Исследование выполнено на 32 пробных площадях различной типологической принадлежности центральной части Мурманской области, заложенных в период с 2015 по 2019 гг [4]. Анализ параметров распределений древостоев в изученных сосняках показал, что в исследованных сосновых лесах средний диаметр древостоя составляет от 5,5 до 9,5 см при давности пожара 40–55 лет до 14–17 см при давности пожара 80–95 лет. Проведенный дисперсионный анализ показал, что средний возраст древостоев в сообществах разной типологической принадлежности достоверно не различается и составляет 66±3 года. Следовательно, при дальнейшем анализе изученные древостои можно объединять в одну группу. Установлено, что диапазон диаметров деревьев сосны обыкновенной в изученных сообществах имеет достоверную связь с возрастом, густотой и суммой площадей сечений древостоя. Результат дисперсионного анализа зависимости диапазона диаметров от возраста показал, наличие трех достоверно различающихся возрастных групп древостоев: возрастом менее 50 лет (диапазон диаметров составляет в среднем 7,7±0,5 см), от 50 до 70 лет (диапазон диаметров – 12,1±0,6 см) и более 70 лет (диапазон диаметров – 17,5±2,0 см); Оценка зависимости диапазона диаметров от густоты древостоя выявила наличие двух групп: древостои с густотой более 1600 экз/га (диапазон диаметров составляет в среднем 6,0 см) и менее 1600 экз/га (диапазон диаметров – 22,0 см). По величине суммы площадей сечений древостоя выделяются две группы: с полнотой менее или равной 13 м2 (диапазон диаметров составляет в среднем 11,0±0,8 см) и более 13 м2 (диапазон диаметров – 15,0±1,0 см). Выводы. Проведенное исследование показало наличие связи диапазона диаметров стволов сосны обыкновенной с таксационными характеристиками изученных древостоев: возрастом, густотой, суммой площадей сечений Величина диапазона диаметров имеет наиболее высокий коэффициент корреляции с возрастом древостоя (r = 0,80) древостоя и более низкий с его густотой (r = 0,58) и полнотой (r = 0,53).
Organizations as Innovations: Examining Changes in Journalism Through the Lens of Newly-Emerging Organizations
Authors: Buschow Christopher , Suhr Maike
Published: November 2023

This article argues that the growing variety of new journalistic organizations and their diversification beyond the traditional newsroom may offer a deeper and broader understanding of change and innovation within journalism. Newly emerging organizations play a multifaceted role in journalism: They are both drivers and results of change; they serve as indicators of the ways in which the structures of journalism and its production processes are evolving; they reveal industry trends early on and enable longitudinal research. Despite the emergence of non-traditional organizations in journalism, existing studies on these new entities remain fragmented and have yet to coalesce into a sustained research program. Against this background, this conceptual article aims to contribute to the ongoing theoretical progress in journalism studies in three ways. First, it identifies key factors of why organizational innovations happen. Second, it systemizes recent studies exemplifying the plurality of new organizations in journalism according to different levels from organization studies, including the field level, the level of organizational populations, and the level of the single organization. Finally, the article proposes a research agenda for establishing “organizations as innovations” as a novel conceptual lens for understanding change and innovation in journalism studies.
On-Demand Learning: Podcasting in an Introduction to Information Systems Course
Authors:   Louisiana Tech University, Van Slyke Craig , Clary Grant ,   Tennessee Tech University, Sutherland Eric A. ,   Louisiana Tech University
Published: November 2023

We live in an on-demand world where digital content can be consumed when and where we want. In this paper, we report on a project that used on-demand content consumption (i.e., podcasts) as supplemental material for higher education students. Each 5-10-minute podcast provides an overview of the assigned chapter readings. Our work makes several contributions. First, we discuss some implications of the current on-demand society on higher education. Second, we provide information regarding podcasting as a method for aligning learning with students’ desires for on-demand media consumption. As part of this discussion, we demonstrate through a survey and download statistics how our low-cost initiative yielded sufficiently positive results to merit continuation. Finally, we detail the process of creating podcasts for our readers to replicate and adapt our initiative, including providing tips and discussing ways to adapt our process to other higher education courses.
TEACHERS’ COMPETENCIES AND STUDENTS’ ATTITUDES TOWARD ICT AT AN EFL SECONDARY SCHOOL
Authors: FARISA Hany , SUNGGINGWATI Dyah , SUSILO Susilo
Published: November 2023

Teachers as educators should have adequate competency in using a variety of media and knowledge to deliver the information to their students in order to use information and communication technologies (ICT) effectively. This study explores teachers’ competencies of ICT in their teaching and students’ attitudes toward ICT in learning English. Three English teachers and their 90 students of eleven graders at one secondary school in one district in East Kalimantan participated in this study. The data were gathered from semistructured interviews, observations, and questionnaires. Using a qualitative approach design concerning phenomenological perspective, the content analysis results have revealed that approximately 70% of the students had a positive attitude toward ICT, while the teachers’ competencies were varied from mostly incorporating all the ICT tools to rarely using them in their classroom. The results suggest that English teachers need to have more professional development programs related to ICT in order to understand and be able to operate the ICT media and tools to teach English. EFL students should aware of their attitude toward ICT in this modern era and firmly use the advancement of ICT for educational purposes.
DISTANCE EDUCATION STUDENTS’ INDULGENCE IN SIX SHARP PRACTICES: GENERAL LINEAR MODELLING OF PREDICTIVE PARAMETERS
Authors: OWAN Valentine Joseph , CHUKTU Onyinye , DIJEH Ann E. , ZAAFOUR Abderrazak , UKAH Julius U. , CHUKWURAH Margaret U. , UBE Denis A. , ASUQUO Michael E. , UWASE Esuong U. , UDIDA Udida J. , OJONG Cyprian O.
Published: November 2023

This study examined the degree to which students indulge in six prominent misconducts in Distance Education Institutions (DEIs). The study also quantified how class size, instructional delivery and institutional policies predict students’ indulgence in sharp practices using a general linear modelling approach. A sample of 871 participants was drawn from 1,742 final-year students across two DEIs in Nigeria. A structured questionnaire was used for data collection. The questionnaire had acceptable psychometric estimates of dimensionality, content and construct validity, as well as reliability. Sharp practices such as cheating, plagiarism, falsification, impersonation, and arm-twisting were more prevalent in large classes, whereas only inducement was higher in small classes. Class size influenced students’ indulgence in sharp practices in DEIs. Instructional delivery and institutional policies negatively predicted students’ indulgence in the six sharp practices. Almost all the six sharp practices correlated positively and significantly, except for impersonation and inducement. Therefore, distance education students who cheat, plagiarize, arm-twist, falsify records, induce lecturers, and promote impersonation are more likely to indulge in other forms of sharp practices. It was concluded that large class sizes, poor instructional delivery, and poorly implemented institutional policies promote sharp practices among distance education students. Based on this conclusion, key policy and research implications are discussed.
Issues of Distribution of Bear Image in Uzbek Novels
Authors: Makhbuba Urazbaeva  , Burkhanova Feruza Abdurazzakovna  , Pardayeva Nigora Kuysinboyevna  , Atabayeva Guzal Farkhadovna  , Kadirova Mashkhura Nasirovna
Published: November 2023

This article explores the issue of the image of women in Uzbek novels created during the period of independence, starting from the first half of the 20th century. The leading principles of creating the image of a woman have been identified. Representatives of the older generation of Abdullah Kadyrov "Days of the Past" took part in determining this issue, "Mehrobdan chaion," Chulpana "Night and Day," Sharp Hoshimov "Between Two Doors," Pyrimkul Kadyrov "Diamond Chamber," Said Aha While Mada's works "Silence" were analyzed, the image of a woman was studied in Togai Murad's novels "You Can't Die in This World," "Fields Left of My Father," created during the years of independence. The leading features of novels created during the years of independence have been identified. Analysis revealed that at the beginning of the 20th century, women were portrayed as weak, victims of the period, and from the second half of the century they were portrayed as working women.
Operator dependence of methods for obtaining metric characteristics of a face with real measurements and digital images
Authors: Yusupova Alexandra A. , Alyabyev Fedor V. , Tsiupko Ekaterina V. , Dyagileva Alina P. , Sukhareva Kristina V. , Chesalov Nazariy P. , Vashchenko Galina A.
Published: November 2023

BACKGROUND: No studies in the scientific literature have established the operator dependence of portrait identification with the manual method of measuring facial parameters in subjects compared with measurements from digital images. The labor costs and accuracy of the measurements with these methods have not been established.
AIM: To establish the operator dependence of methods of real-face measurement and measurement on digital images.
MATERIALS AND METHODS: Facial parameters were instrumentally measured in 24 Caucasian women aged 19–20 years who were studying at the Professor V.F. Voino-Yasenetsky Krasnoyarsk State Medical University by four researchers independently of each other. The same type of standard digital photography of each subject’s face was taken in five projections, followed by a comparison of the results of real measurements with digital ones.
RESULTS: When comparing the results of facial measurements obtained from digital images and manual method, an error was observed both in the measurements of one parameter by one researcher using two methods and in the excellent results obtained by other researchers. However, the greatest deviations were observed with the manual method, which may be due to the dependence of measurements on the operator.
CONCLUSION: With a streamlined and methodically verified approach to working with digital facial images, this technique is more accurate and less labor-intensive than real measurements because of the absence of operator dependence, which can be used in investigating crimes.
Direction Estimates for Short-Period P-Waves on Three-Component Stations and Arrays
Authors: Gibbons Steven J.
Published: November 2023

P-arrival backazimuth estimates can be crucial in locating poorly constrained seismic events. Correlating short windows of the vertical waveform with corresponding windows of the radial rotation for different backazimuths can provide estimates, but these are often uncertain and biased due to skewness in the Z–R correlation functions. Assessing how well cosine curves centered on different backazimuths match the Z–R correlation functions provides more reliable estimates that depend less upon the time-window used. Stacking best-fit-cosine curves from neighboring three-component stations improves stability further in a form of array-processing that does not require coherence between the waveforms themselves. We demonstrate for recordings of North Korean nuclear tests at the Pilbara 3C array in Australia that the biases in the Z–R correlation functions vary greatly between adjacent stations. This bias is reduced both by the cosine curve fitting and stacking operations. We advocate obtaining backazimuth estimates for all P arrivals at three-component stations globally. This could improve phase association and event location, identify sensor orientation problems, and provide baseline backazimuth corrections and uncertainty estimates. We propose two benchmark datasets for developing, documenting, and comparing backazimuth estimation algorithms and codes. All the data and code used to generate the results presented here are open.
MODIFICATION OF THE 5-AXIS TOOLPATH TO INCREASE THE TURBINE HUB SURFACE QUALITY
Authors:   Czech Technical University in Prague, Faculty of Mechanical Engineering, Department of Production Machines and Equipment (RCMT), STEJSKAL MICHAL , PESICE MATEJ ,   Czech Technical University in Prague, Faculty of Mechanical Engineering, Department of Production Machines and Equipment (RCMT), VOTRUBA VOJTECH ,   Czech Technical University in Prague, Faculty of Mechanical Engineering, Department of Production Machines and Equipment (RCMT), KOVALCIK JAROSLAV ,   Czech Technical University in Prague, Faculty of Mechanical Engineering, Department of Production Machines and Equipment (RCMT), KRATENA TOMAS ,   Czech Technical University in Prague, Faculty of Mechanical Engineering, Department of Production Machines and Equipment (RCMT), VAVRUSKA PETR ,   Czech Technical University in Prague, Faculty of Mechanical Engineering, Department of Production Machines and Equipment (RCMT), RYBIN JAROSLAV ,   Czech Technical University in Prague, Faculty of Mechanical Engineering, Department of Production Machines and Equipment (RCMT)
Published: November 2023

This industrial article focuses on the finishing machining of workpieces made of aluminium alloy EN AW 7075 with a freeform shape, utilizing minimal material stocks. These workpieces are widely used in sectors like aviation and the energy industry. In these sectors, there is a pressing demand for high-quality production in the initial attempt, eliminating the need for subsequent post-processing operations. The reason for this is to save material and reduce production time. The paper, therefore, deals with a method that involves analysing the shape of a spherical end mill in relation to surface roughness and quality, followed by a mathematical recalculation of the tool path. This approach allows to adjust the machining settings during the preparation phase in order to achieve satisfactory surface quality across the entire machined surface. This method was successfully validated during the final surface treatment of the turbine hubs.
ANALYSIS OF THIN-WALLED COMPONENTS WITH INTERNAL MICROSTRUCTURE DESIGN MANUFACTURED BY LPBF
Authors:   Universidad del País Vasco (UPV/EHU), Department of Mechanical Engineering, Martinez-Aguirre M. , Kumar S. ,   Indian Institute of Technology-Kanpur, Department of Mechanical Engineering, Gómez G. ,   Universidad del País Vasco (UPV/EHU), Department of Mechanical Engineering, Holgado I. ,   Centro de Fabricación Avanzada Aeronáutica (CFAA), González-Barrio H. ,   Universidad del País Vasco (UPV/EHU), Department of Mechanical Engineering, Calleja-Ochoa A. ,   Universidad del País Vasco (UPV/EHU), Department of Mechanical Engineering, López de Lacalle L.N. ,   Universidad del País Vasco (UPV/EHU), Department of Mechanical Engineering
Published: November 2023

Additive Manufacturing techniques represent a revolution for the design of certain engineering components traditionally subject to a design highly influenced by the manufacturing process linked to the manufacture of the component. Additive Manufacturing techniques therefore allow components with different internal and external structures to be manufactured. Thus, components formed by an internal microstructure are of special interest due to their high strength-to-weight and high stiffness-to-weight properties. This work investigates the hybrid fabrication of curved thin-walled Inconel 718 with internal microstructural supports fabricated by laser powder bed fusion (LPBF). The outer walls are made up of solid surfaces with a fixed curvature and thickness, while the internal structure of the pieces is made up of internal microstructures that vary at different angles of inclination. Finally, the outer surfaces of the piece have been milled. Eventually, the dimensional quality of the components and their internal microstructure has been analysed.
MODELING OF CUTTING TEMPERATURE IN SCREW WHIRLING MILLING DURING THE TWO CUTTING STAGES
Authors:   Anhui University of Science and Technology, College of Mechanical Engineering, Liu Chao , Huang Shaofu ,   Anhui University of Science and Technology, College of Mechanical Engineering, He Yan ,   Chongqing University, State Key Laboratory of Mechanical Transmission, Huang Zunpeng ,   Anhui University of Science and Technology, College of Mechanical Engineering, Yang Zidong ,   Anhui University of Science and Technology, College of Mechanical Engineering
Published: November 2023

Temperature analysis in the manufacturing phase of the product is necessary for improving the operational performance of the workpiece. In screw whirling milling, the analysis of cutting temperature is different from turning or milling due to the complicated contact characteristics between the tool, workpiece and chip. In this study, a temperature model is developed for predicting the temperature distribution of the cutting area in screw whirling milling at the two cutting stages. Temperature experiments on the ball screw shaft are carried out in whirling milling machine under different cutting conditions to verify the proposed model. The maximum temperature of the cutting area increases with the cutting speed at first and decreases subsequently. The maximum temperature increases with the rotation of the tool ring and then decreases in one cut.
FUNDAMENTAL ANALYSIS ON THE DYNAMIC BEHAVIOR OF TOOLS WITH STRUCTURED FUNCTIONAL SURFACES IN CUTTING OPERATIONS
Authors:   TU Dortmund University, Institute of Machining Technology (ISF), Jaquet S. , Baumann J. ,   TU Dortmund University, Institute of Machining Technology (ISF), Garcia R. ,   TU Dortmund University, Institute of Machining Technology (ISF), Biermann D. ,   TU Dortmund University, Institute of Machining Technology (ISF)
Published: November 2023

The productivity of machining processes is often limited by the occurrence of dynamic effects. The investigated approach intends to counteract tool deflections, and thus to damp and disrupt chatter vibrations by using milling tools with defined functional structures on the flank faces at the frontal cutting edges. For the fundamental investigation of the interactions between structural geometric properties and the tool-workpiece interaction, the engagement situation was geometrically evaluated on a highly abstracted level. Subsequently, hypotheses derived from this were validated experimentally in analogy tests with linear cutting motion. In these cutting experiments, dynamic deflections were induced by an external excitation of the specifically compliant modular tool system. Finally, the technologically most relevant structure variants were applied to milling tools and evaluated with regard to their dynamic behavior. This investigation was preceded by a simulation-based analysis of the material removal on the frontal flank face as a function of the process configuration, which is characterized by multiple intersecting cuts in milling processes. By specifically optimizing and coordinating the structure design and the process configuration, an increase in process stability and thus productivity of at least 100% could be achieved.
NUMERICAL STUDY OF EFFECT OF FLANK WEAR ON HEAT TRANSFER ABILITY IN HIGH-SPEED ULTRASONIC VIBRATION CUTTING INTERFACES
Authors:   Beijing Key Lab of Precision/Ultra-precision Manufacturing Equipments and Control, Department of Mechanical Engineering, Tsinghua University, Zhang Xiangyu , Wang Dongyue ,   Shanghai Jiao Tong University and Chiba University International Cooperative Research Center (SJTU-CU ICRC), Peng Zhenlong ,   School of Mechanical and Power Engineering, Zhengzhou University
Published: November 2023

High-speed ultrasonic vibration cutting shown great advantages by cutting temperature reduction due to periodic opened cutting interfaces for direct heat convection with coolants. To figure out accurate heat transfer ability, a 2-dimensional simplified model was developed and computational fluid dynamics (CFD) was used to calculate heat flux and Nusselt number. Three flank wear lengths for initial, initial-stable transition and stable stages were chosen and comparisons made between CFD results and wear progresses indicated that heat transfer ability demonstrated better performance during the stable wear stage at low cutting speed. As cutting speed increased the effect of ultrasonic vibration was weakened.
FROM THE TRADITIONAL MULTILATERATION TO THE INTEGRATED MULTILATERATION APPROACH: A ROADMAP TOWARDS THE AUTOMATIZATION OF VOLUMETRIC ERROR MAPPING PROCESS FOR LARGE MACHINE TOOLS
Authors:   Tekniker, Mechanical Engineering Department, Egaña F. , Mutilba U. ,   Tekniker, Mechanical Engineering Department, Kortaberria G. ,   Tekniker, Mechanical Engineering Department, Eguskiza J. ,   Tekniker, Mechanical Engineering Department, Check B.A. ,   Tekniker, Mechanical Engineering Department
Published: November 2023

Multilateration-based volumetric error mapping is gaining widespread adoption in the coordinate measurement machine and machine tool industry as the most effective approach for geometric characterization of large-size machines. In the traditional method, tracking interferometers are placed on the machine table while the measurement retro-reflector moves with the spindle. However, this approach has several limitations, including manual instrument manipulation and a sequential measurement scheme that hinders unattended execution. To overcome these limitations, the integrated multilateration method has been introduced, which addresses these challenges and reduces measurement uncertainty. This method offers the potential for fully autonomous volumetric error mapping of large-size machines and enables the development of new functionalities such as traceable coordinate measurement with large machine tools. This research presents the roadmap followed by the authors to automate the volumetric error mapping process for large machine tools. It outlines the current status of the technology, starting from the conceptual development and culminating in the experimental results obtained from real industrial machine tools.
Synaesthesia in a Modern scientific Paradigm
Authors:   V. I. Razumovsky Saratov State Medical University, Prokofyeva L.P.
Published: November 2023

The author surveys modern definitions of synaesthesia, analyses research methods of this phenomenon, suggests the classification on basis of combining of linguistic, psychological, cultural studies approaches.
Juridical Vocabulary normalization in the Process of Harmonizing Canada’s Provincial and Federal Legislation
Authors:   Saratov State Law Academy, Mikhailova L.Yu.
Published: November 2023

The article considers the problem of adjustment in English and French systems of terminology illustrated by Canada’s juridical practice.
Raûf Yektâ Bey Türk Mûsikîsi’nin 24’lü Ses Sistemini Risâletü’ş-Şihâbiyye’den mi Almıştır?
Authors: ÖNCEL Mehmet , YAHŞİ Turgut
Published: November 2023

Osmanlı mûsikîsinin nazari sistemi, Safiyyüddin Urmevî (öl. 693/1294) ve Abdülkadir Meragî’nin (öl. 838/1435) eserleri üzerinden geliştirilmiştir. İlk dönem itibariyle bakıldığında nazarî anlamda 24 tonlu ses sistemi işlenmemiş olsa da pratikte bunun kullanıldığı açıktır. Ancak nazarî anlamda Urmevî’nin başlatmış olduğu 17 ses sistemi 20. yüzyıla kadar kullanılmaya devam etmiştir. Bu yüzyılla birlikte Raûf Yektâ’nın (öl. 1935) gayretleri ile Türk mûsikîsi nazariyat sistemi farklı bir noktaya evrilmiştir. Burada önümüze eşit olmayan 24’lü ses sistemi çıkmaktadır. 24 tonlu ses sisteminin yazılı olarak ilk izleri La Borde’nin (öl. 1208/1794) eserinde görülmektedir. Sonrasında Muhammed ʿAttar (öl. 1243/1828) ve öğrencisi Mikail Meşakka (öl. 1305/1888) ile 24 tonlu ses sistemi ile şöhret bulmuştur. Bu sistemi de içinde barındıran Meşakka’nın Risâletü’ş-Şihâbiyye fi’ṣ-ṣınâati’l-mûsikiyye isimli eseri modern Arap mûsikîsinin şekillenmesinde önemli bir köşe taşı olmuştur. Bu sistemi bir gazete yazısı vesilesi ile fark eden Raûf Yektâ, 24 eşit parçaya ayrılmış bu nota sisteminin Türk mûsikîsinde özellikle ara seslerin isimlendirilmesinde büyük kolaylık sağladığını tespit etmiştir. Yektâ’nın bu tespiti, Meşakka’nın sisteminde yer alan nota isimleri ile bazı farklılıklara rağmen büyük oranda benzerlik göstermiştir. Yektâ’nın Türk mûsikîsine sunduğu bu sistemin, Meşakka’nın sistemi ile temel farkı Yektâ’nın eşit olmayan (gayr-i müsavi) sesler şeklinde bir tercihte bulunmasıdır. Bu çalışmada yine 24 tonlu ses sisteminin ilk olarak kim tarafından ortaya konulduğu ile ilgili bilgilere yer verilmiştir. Ancak bu konu ile ilgili net bir veriye ulaşılamamıştır. Türk mûsikîsi açısından bakıldığında Yektâ’nın açtığı -her ne kadar Yektâ tarafından ortaya konulmasa da- bu sistemsel çığır Arel-Ezgi-Uzdilek üçlüsü ile günümüzün nazariyat temellerini atmasını sağlamıştır. Bu araştırmada Meşakka’nın eserinde yer verdiği birtakım kavramların Türk mûsikîsinde yer alan kavramları ile muhteva açısından aynı olduğu tespit edilmiştir. Murat Bardakçı’nın bir yazısında açıkça belirttiği ve Rauf Yektâ’nın da Türk mûsikîsinin ses sistemini oluşturmasında istifade ettiğini düşündüğümüz Mikail Meşakka tarafından yazılan Risâletü’ş-Şihâbiyye fi’ṣ-ṣınâati’l-mûsikiyye isimli eseri bu çalışmanın odak noktasıdır. Makalenin amacı 24 tonlu ses siteminin ilk izlerine kadar ulaşmak ve bunun Türk musikisi ile irtibatını ortaya koymaktır. Yapılan literatür çalışmasında gerek Mikail Meşakka’ya dair gerekse 24’lü ses sisteminin izlerinin ilk nerelere dayandığına dair ayrıntılı bir çalışma yapılmamıştır. Bu yönüyle bu sorulara cevap aramak makalenin özgünlüğünü oluşturmaktadır. Nitel araştırma yöntemi, doküman taramasıyla elde edilen bilgiler veri analiziyle ele alınmıştır.
System certyfikacji ''czysta turystyka'' podstawowe przesłanki decyzji wdrożeniowej
Authors: Dziuba Radosław
Published: November 2023

Poland, after a short recession resulting from the global crisis, again recorded growth in foreign tourist arrivals. This allows the conclusion that tourism will become in the coming years, one of the main directions of development Polish. In the wake of the development of tourism in Poland should take into account the need to increase the accommodation in hotels. This is necessary in order to fully exploit the potential of the country in this field. The hotels industry is so pro-development trend of tourism in Poland has a chance to growth. Beyond the basic offer, hotels need for additional distinguishing features compared to its nearest competitors such distinction through the use of certified sustainable solutions "Clean Tourism". The aim of this paper is to analyze the basic premises deployment decisions assumptions at the example of ecology certification "Clean Tourism" and an incentive to certify the hotel facilities.
VALORIZATION AND SPATIAL TYPOLOGY OF LODZ'S RESIDENTIAL RESOURCES DURING THE TRANSFORMATION PERIOD
Authors: Dzieciuchowicz Jerzy
Published: November 2023

A specific spatial structure of Łódź’s residential resources was distinguished in Łódź in the age of political transformation. Different features of these resources (336,1 thousand apartments in 2008) create different spatial patterns, which are usually highly variable. A synthetic approach is justified in this case, as this issue was not frequently subject to independent study. The object of this study is valorization and spatial typology of Łódź’s residential resources in conditions typical for the transformation period. The multivariable analysis of these resources involves distribution and intensity of residential development, its dynamics (in years 1988−2002), its age, types of ownership, as well as size of buildings and apartments, technical facilities in the apartments and population density in the apartments. Specific features of residential resources were investigated according to data from 2002 national census. The city was divided into 61 housing estate units. During the valorization of residential resources, a synthetic variable, being the function of 13 diagnostic features which are the stimulants of residential standard, was used. In order to elaborate the spatial typology of residential resources, the K-mean method was used, as one of the most effective iterative optimization methods used in numerical taxonomy. There were 19 typological features distinguished.
Etnomathematics: exploration sanitary industry center of Malang
Authors: Intsani Nadila Choirunnisa' , Mukti Taufiq Satria , Rofiki Imam
Published: November 2023

This study aims to explore the mathematical elements contained in the center of the sanitation industry in Malang City. The Sanitary Industry Setra is in the form of flower pots, gravestones, tombstones, fountains, hand washing stations, chairs, and so on. The object is an object of exploration based on an ethnomathematical point of view. This study uses a qualitative approach to the type of ethnographic research. The subjects in the study were sanitary ware craftsmen in the Karangbesuki area of Malang City. The subject is experienced and has a fairly large turnover. Data collection techniques in the study were carried out by observation or direct observation in the field, interviews, and also by studying literature. This research will provide evidence that without realizing it, people have applied the concepts of comparison, calculation and mathematical measurement in creating an object of crafts that have been carried out since ancient times. The mathematical implementation carried out by craftsmen produces crafts in the form of spatial geometric shapes such as: blocks, tubes, half balls, and others. In creating craft objects, researchers also found the concept result from geometric transformations such as: of translation, rotation, and also reflection on some of the crafts produced.
The use of race quiz media to increase students interest in learning mathematics on the material of whole numbers class VII D SMP Negeri 3 Lawang academic year 2023-2024
Authors: Primandanu Teguh
Published: November 2023

With the advancement of science and technology, it is expected to facilitate students in learning mathematics. One method that can be used to learn mathematics is through technology-based media that can be accessed easily by teachers and students. This research is a collaborative classroom action research that aims to increase the interest in learning mathematics of students in class VII D SMP Negeri 3 Lawang in the 2023-2024 school year by using the "Race Quiz" media. The subjects in this study were students of class VII D SMP Negeri 3 Lawang in the academic year 2023-2024 as many as 32 students consisting of 16 male students and 16 female students. The cycle in this Classroom Action Research uses the Kemmis Me Taggart model with the stages of planning, implementation, observation, and observation The instruments used to collect data were observation sheets of learning activities, student response questionnaires for each cycle, and interviews with mathematics teachers. The data obtained was analysed using quantitative descriptive analysis to determine the increase in students' interest in learning mathematics using the "Race Quiz media. Based on pre-cycle data, it shows that students' interest in learning mathematics is 68% so that it can be categorised as sufficient. This class action research was conducted in 2 cycles. The observation results showed an increase in students interest in learning mathematics in the learning process by 6% from 76% in cycle I to 82% in cycle II, so it can be categorised as very high. Therefore, the existence of technology-based learning media is expected to increase students' interest in learning mathematics
A Rationality Study of Antihypertensive Drugs Usage in Preeclampsia Patients in the Private Hospital
Authors: Wijaya Dhani , Rohmah Afwa Syahara , Syarifuddin Sadli , Rahmadanita Fathia Faza
Published: November 2023

Preeclampsia is a hypertension that happens in pregnancy of ≥ 20 weeks and occurs with proteinuria. Preeclampsia is also the highest cause of mother’s death second place in Indonesia. According to that, a study of rationality is needed concerning medicine usage as one of the efforts to determine which medicine is accepted by the rational patient so that the expected therapeutic effect is achieved and does not harm the lives of the mother and baby. The purpose of this research is to determine the profile and rationality of anti-hypertension medicine usage on pregnant mothers with preeclampsia at a private hospital in Malang. This is an observational descriptive research that uses retrospective data. The sample-taking method of this research is using a total sampling method. This research data is served on a diagram or table and percentage. The result of this research is that 3 kinds of anti-hypertension medicine are used: nifedipine 78%, amlodipine 17%, and candesartan 5%. The rationality study of the use of antihypertensive drugs in this study obtained 78% correct indication, 100% correct drug, 93% correct dose, 62% correct interval of administration, and 100% correct patient. This study shows that the usage of antihypertensive drugs in preeclampsia is rational in several parameters.
A Network Pharmacology of Beluntas (Pluchea indica) on Immunity Cases
Authors: Fauzi M Amir , Muchlisin M Artabah , Jamil Ahmad Shobrun , Almuhtarihan Irsan Fahmi
Published: November 2023

COVID-19 is classified as an outbreak related to the human immune system. The process of spreading was indeed quick, which made this outbreak a particularly dangerous pandemic. As of March 10, 2023, Indonesia had recorded 6,738,225 positive cases and 160,941 deaths from COVID-19 in 2020. The aim is to curb virus spread by boosting the immune system through antibody production. Studies suggest that certain Indonesian plants have immunomodulatory potential. This study aimed to determine the protein network associated with the body's immune system, which was activated by giving beluntas (Pluchea Indica). The research method used is descriptive in silico analysis using a online databases: KNApSAck, Dr. Duke, Pubchem, Swiss ADME, Swiss Target Prediction, Gene Cards, Venny, STRING, and KEGG. Based on the results of pharmacological network analysis, the P. indica contains 234 secondary metabolites, 126 of which have high bioavailability. Proteins associated with P. indica contain 1317 compounds, and those related to immunomodulators contain 1380 proteins. 340 proteins were found to have interacted with P. indica, all linked to immunomodulation, suggesting its potential for developing treatments for immune-related disorders through further research Based on KEGG Pathway analysis, there are five critical pathways in the immunomodulatory system, namely Th17 cell differentiation, IL-17 signaling pathway, T cell receptor signaling pathway, Fc epsilon RI signaling pathway, and TNF signaling pathway. There is 17 compound that can be an immunomodulator because it interacts with five critical pathways in the immunomodulator system.
Potential of Secondary Metabolite of Jasminum sambac as Diabetes Mellitus Medicine by Molecular Docking Method
Authors: Alghifari Mochammad Rehan , Jamil Ahmad Shobrun , Muchlisin M Artabah
Published: November 2023

Diabetes mellitus (DM) is a non-infectious disease with a high prevalence in Indonesia. The study explored the potential of the phytochemical component of Jasminum sambac to treat DM. The potential of Jasminum. sambac as a candidate for DM therapy was demonstrated through in silico analysis using several databases and computer-aided drug discovery tools. The bioactive compounds analyzed were obtained from KnapSACK databases. The screening was done to find compounds by estimating bioavailability prediction on the SwissADME. The SwissTargetPrediction tool connects predictions of target proteins from compounds that pass screening to various probable proteins and utilizes the String-DB to show the network between target proteins and associated diseases. After finding the target protein, continue docking the chemical compound to the target protein using PyRx with AutoDock 4.2.6. The search results for the compounds in Jasminum sambac found nine active substances with good bioavailability. The results of the pharmacological network found four proteins associated with Jasminum sambac, among others: GCGR, GSK3B, PPARA, and PPARG. In addition, in-depth analysis was done on the molecular interactions that occurred, how these compounds bind the enzymes found in humans, and their potential to be inhibitors of diabetes mellitus. Proteins such as GCGR, GSK3B, PPARA, and PPARG bind to the compounds found in Jasminum sambac, such as (-)-alpha-cadinol and linalyl benzoate. Thus, it can be said that Jasminum sambac can have anti-diabetic activity.
Bioavaibility Evaluation and Molecular Docking of Cananga odorata Plant as Anti-Inflammatory Potential Against Crohn’s Disease
Authors: Annisadila Shindy , Jamil Ahmad Shobrun , Muchlisin M Artabah
Published: November 2023

Crohn's disease is a chronic inflammatory bowel disease (IBD) that affects the digestive tract. One of the potential targets for this disease is LRRK2. Kenanga (Cananga odorata) is known to have anti-inflammatory effects. The study aims to identify the potential of the secondary metabolite compounds found in C. odorata against LRRK2 in silico. The KnapSack database was used to identify the secondary metabolite compounds of C. odorata, SwissADME was used to find the compound with high bioavailability with the Boiled-EGG method, and PyRx with the AutoDock was used for molecular docking. According to the docking results, three compounds are potentially inhibiting LRRK2, namely (+)-Reticuline with a binding energy of -9.04 kcal/mol and a prediction of inhibition constant (pKi) of 237.71 nM, benzyl benzoate with a binding energy of -8.19 kcal/mol and a prediction of inhibition constant (pKi) of 994.29 nM and benzyl salicylate with a bonding energy of -8.22 kcal/mol and a prediction of inhibition constant (pKi) of 942.48 nM.
The Role of Literature Education in the Posthuman Era: Reading Death of a Salesman
Authors:   The Korean Society For Teaching English Literature, Kim Sooim , Chung Hyejin
Published: November 2023

The purpose of this study is to explore the necessity of literature education in the post-human era where uncertainty is amplified due to the rapid development of science and technology. What is fundamentally necessary in a rapidly changing reality that exceeds the capacity of human consciousness? It involves introspection on the meaning of human life and existence. This is because what can lead the future society in a desirable direction, which is difficult to predict, is ultimately related to human ethical duty. One possible way is through reading literature that encompasses human life. Literature has secured the resources of stories that were difficult for mankind to imagine or guess over countless times, gained persuasive power, and expanded its scope enough to prepare for the shock of a rapidly changing reality. In this context, this study aims to examine the need to reconsider the role of literature education. It does so by introducing aspects of a literature class, particularly focused on Death of a Salesman, conducted as a liberal arts course at a 4-year university in Seoul. This is in response to the reality that the position of literature has been narrowed even within the university curriculum.
Dijital Oyun Bağımlılığı ve Öz Yeterliğin Ortaokul Öğrencilerinin Sosyal Bilgiler Dersi Akademik Başarısına Etkisi: Bir Yapısal Eşitlik Modeli
Authors: DEMİR Yılmaz
Published: November 2023

Bu araştırmada ortaokul öğrencilerinin sosyal bilgiler dersi akademik başarıları üzerinde dijital oyun bağımlılıkları, öz yeterlikleri (sosyal, duygusal ve akademik) ile çeşitli demografik (cinsiyet, ebeveyn eğitim durumu) özelliklerin etkisinin yapısal eşitlik modeliyle sorgulanması amaçlanmıştır. Araştırmada nicel araştırma yöntemlerinden olan betimsel analiz yöntemi kullanılmıştır. Araştırmanın çalışma grubunu 2022-2023 eğitim öğretim yılında Kilis ili merkez ilçedeki üç farklı ortaokulda öğrenim görmekte olan 474 ortaokul öğrencisi oluşturmaktadır. Araştırmada yapısal eşitlik modeli temel alınarak hipotezlenen yol diyagramı geliştirilmiştir. Bu modele göre öğrencilerin cinsiyeti, anne ve baba eğitim durumu dışsal değişkenleri; dijital oyun bağımlılığı, sosyal, duygusal ve akademik özyeterlikleri aracı ve içsel değişkenleri; sosyal bilgiler dersi akademik başarıları ise sadece içsel değişkeni oluşturacak biçimde ele alınmıştır. Çalışmada yer verilen tüm dışsal değişkenlerin içsel değişkenler üzerinde doğrudan ve dolaylı etkilerinin olduğu hipotezlenmiştir. Verilerin analizinde Mplus 7 istatistik programı kullanılmış ve yapısal eşitlik modeliyle veriler test edilmiştir. Araştırma sonucunda anne ve baba eğitim durumunun sosyal bilgiler akademik başarısı üzerinde doğrudan, cinsiyet değişkeninin doğrudan ve dolaylı, dijital oyun bağımlılığı ve sosyal öz yeterliğin dolaylı ve aracı, akademik öz yeterliğin ise doğrudan ve aracı etkisinin anlamlı düzeyde olduğu tespit edilmiştir. Ayrıca dijital oyun bağımlılığının akademik öz yeterlik üzerinde doğrudan ve dolaylı, sosyal ve duygusal öz yeterlik üzerinde ise sadece doğrudan etkisinin anlamlı düzeyde olduğu belirlenmiştir. Ek olarak duygusal ve sosyal öz yeterliğin akademik öz yeterlik üzerinde etkinin de anlamlı düzeyde olduğu sonucuna ulaşılmıştır.
Atypical location of the thyroid node in the upper section of the neck (clinical observation)
Authors: Styazhkina S. N. , Rysov A. I. , Fedulova T. V. , Gasanova M. A. , Chakmina M. I. , Tursukova A. A. , Gil'mutdinov A. V.
Published: November 2023

Currently, there is an increase in the number of patients with nodular formations of the thyroid gland (TG), which requires preoperative diagnostics, which allows to detect in a timely manner follicular neoplasia and highly differentiated forms of cancer, colloid goiter with compression of the neck organs, nodular and diffuse toxic goiter (DUS) [5]. Most often, the nodes are located in the thyroid gland, but there are cases with atypical localization. Ectopia of the thyroid gland, or thyroid ectopia (from the Greek “ektopos”, i.e. “displaced”) is the presence of its atypical tissue in a place that is not characteristic of normal localization. This pathology develops due to a violation of the migration of progenitor cells of the thyroid gland during its embryonic development. The prevalence of thyroid ectopia is 1 per 100,000–300,000 people, 1 case per 4–8 thousand patients with thyroid pathology. Among the sick in 65–80 % of cases are women. According to the studied literature, thyroid ectopia can become a source of malignancy, so timely diagnosis and surgical treatment is necessary to prevent the development of life-threatening conditions. An analysis of a clinical case of atypical location of a thyroid nodule with a suspected oncological neoplasm in case of recurrence after hemithyroidectomy was carried out.