bluuebunny/crossref_metadata_2025 huggingface dataset:
Efektivitas Program Peningkatan Peranan Wanita Menuju Keluarga Sehat Sejahtera (P2WKSS) di Kelurahan Kebon Gedang Kota Bandung
Authors: Rizky Indriani Dea , Anggun Artisa Rike
Published: October 2023

Penelitian dilakukan untuk memahami efektivitas program Peningkatan Peranan Wanita Menuju Keluarga Sehat Sejahtera (P2WKSS) di Kelurahan Kebon Gedang Kota Bandung. Tujuan dari kegiatan penelitian ini untuk mengetahui efektivitas program mengenai pemberdayaan perempuan menganalisis hambatan yang dihadapi dalam pelaksanaan program dan memberikan upaya pada program Peningkatan Peranan Wanita Menuju Keluarga Sehat Sejahtera (P2WKSS). Pendekatan menggunakan pendekatan kualitatif dengan menggunakan metode wawancara, observasi dan studi dokumen. Informan penelitian yaitu Dinas Pemberdayaan dan Perlindungan Anak Kota Bandung, Kasi Kelurahan Kebon Gedang, stakeholder, dan sasaran penerima program. Dalam menganalisis efektivitas program menggunakan teori pengukuran efektivitas program dari Edy Sutrisno (2010) yaitu Pemahaman Program, Tepat Sasaran, Tepat Waktu, Tercapainya Tujuan, dan Perubahan Nyata. Hasil penelitian ini membuktikan bawa Efektivitas Program Peningkatan Peranan Wanita Menuju Keluarga Sehat Sejahtera (P2WKSS) di Kelurahan Kebon Gedang Kota Bandung belum cukup efektif karena masih ada beberapa kekurangan sesuai dengan teori pengukuran efektivitas program menurut Edy Sutrisno (2010). Hal ini dibuktikan dengan adanya perubahan dan pemecahan masalah dilokasi binaan selama satu tahun program berjalan belum tercapai semua terutama pada bidang kapasitas pemerdayaan sumber daya manusia, pemahaman program yang dilakukan belum maksimal, serta ketepatan waktu belum memberikan manfaat dalam jangka panjang.

Kata Kunci : efektivitas program, pemberdayaan, perempuan.
Introducing molasses as a new additive in papermaking
Authors: FAHMY TAMER Y.A.
Published: October 2023

This study introduced, for the first time worldwide, molasses as an additive in papermaking. The introduction of molasses as an additive in papermaking resulted in paper composites with greater breaking length and remarkably higher water retention value (WRV), compared with paper that does not have molasses as an additive. Previous studies have shown that incorporating the cell wall microstructure of cellulose fibers with sucrose greatly enhanced the breaking length and WRV. It is well established in the literature that using gums (including starch) as additives in papermaking enhances paper strength. Molasses, which contains sucrose and gums (including starch) is a byproduct of the sugar industry and is cheaper than sucrose. Mercerization of pulp fibers before loading them with molasses was shown to greatly enhance the positive effects produced by loading with molasses.
LUTAS CORPORAIS NA PESPERCTIVA DE INCLUSÃO: POSSIBILIDADES PARA UM ALUNO CADEIRANTE
Authors: Felipe Dionny , Junior da Silva Daniel , Pereira Pires Flávio , Gonçalves de Abreu José Roberto , Do Nascimento Megal Lucas , Reis Lopes Thiago
Published: October 2023

A presente pesquisa, possui como principal objetivo, propor uma sequência didático-pedagógico para o ensino das Lutas Corporais na perspectiva da inclusão para um aluno cadeirante, propondo assim, reflexões sobre a inclusão de um estudante cadeirante nas aulas de Educação Física no âmbito escolar. Desse modo, foi utilizado de pano de fundo para a construção do presente artigo, o documento norteador da rede pública municipal de São Mateus-ES, bem como autores que dialogam com o tema proposto. A metodologia adotada foi a de pesquisa de campo, sendo planejada 7 aulas que seguem uma progressão pedagógica por meio de atividades lúdicas. Conclui-se que, as Lutas Corporais na perspectiva da inclusão pode ser um relevante tema para a Educação Física Escolar, tendo em vista as diversas possibilidades para a contribuição com a formação integral do aluno enquanto sujeito participativo e crítico na sociedade. Além disso, espera-se que o trabalho em tela possa auxiliar futuros estudos nas áreas relacionadas a pesquisa.
Reseña de Stanley y Vass (2018) Questions of Culture in Autoethnography
Authors: Aranda Delgado María Magdalena
Published: October 2023

A lo largo de los apartados que lo componen, el libro aborda una serie de reflexiones que evidencian los aciertos de utilizar el método autoetnográfico. Cada uno de los artículos es una muestra en sí misma de la amplia variedad de posibilidades creativas de las que se puede echar mano para profundizar, indagar y hacer entendibles los fenómenos socioculturales desde la óptica de quién investiga. Con autoetnografías evocativas, críticas, colaborativas, comunitarias o duoetnografías, las y los diferentes autores exponen cómo logran resolver una de las preocupaciones inherentes a la investigación cualitativa: ligar comprensiva y analíticamente lo histórico, político y cultural con las experiencias concretas individuales.
Handbuch Strafrecht Besonderer Teil Band 1
Authors: Wessely Wolfgang
Published: October 2023

Rasch und leicht handhabbar zum Wesentlichen zu gelangen - durch die immer schwerer zu bewältigende Informationsflut im Internetzeitalter ist dies auch im Bereich der Rechtswissenschaften zunehmend zur zentralen Herausforderung geworden. Hier setzt dieses Werk an: Es bietet dem Leser eine kompakte, systematische, vor allem aber an den Bedürfnissen des im gerichtlichen Strafrecht tätigen Praktikers angelegte Darstellung des Besonderen Teils des Strafgesetzbuchs. Besonderes Augenmerk wird dabei den in der strafgerichtlichen Praxis häufig auftretenden Fragestellungen, insbesondere jener der "Einschlägigkeit", geschenkt. Weiters wird auf deliktspezifische Besonderheiten des Allgemeinen Teils hingewiesen. Mit Blick auf den primären Adressatenkreis stützt sich das Praxishandbuch in erster Linie auf die einschlägige Rechtsprechung des Obersten Gerichtshofs, ohne jedoch zentrale Lehrmeinungen unberücksichtigt zu lassen.
INTEGRATION OF SOCIOSCIENTIFIC APPROACH AND DESIGN THINKING: AN ENTREPRENEURIAL CREATIVE THINKING MODULE FOR STEM EDUCATION
Authors: Arifin Sufirman , Siew Nyet Moi
Published: October 2023

This study was conducted to i) ascertain the validity, reliability, and feasibility of a module based on the socioscientific issue approach and design thinking model (SIA-DT), and ii) assess its effects on the entrepreneurial creative thinking (ECT) in STEM education. The first phase of ECT module validation was conducted with the assistance of three expert evaluators and 32 students. A 5-point Likert scale questionnaire and the ECT test were used to collect data. The second phase consists of evaluation using a quasi-experimental design with a Pre-Post Test of Non-Equivalent Control Groups. A total of 64 Form Four students were divided into two groups: SIA-DT (n = 32) and control (n = 32). The ECT module has a high validity value and an acceptable Cronbach's alpha reliability of .92. The ECT Module's feasibility was substantiated by a mean score of 4.71. The results of the independent-sample t-test prove that there is a significant difference in the post-test for students in the SIA-DT group compared to the control group in ECT and five constructs of ECT. In conclusion, these findings demonstrate that the ECT Module is valid, reliable, and feasible in STEM education and that it is effective in enhancing students' ECT.
Keywords: design thinking model, entrepreneurial creative thinking, module development, socioscientific issue approach, STEM education
DETERMINING PRE-SERVICE SCIENCE TEACHERS' UNDERSTANDING ABOUT STEM EDUCATION
Authors: Keçeci Gonca
Published: October 2023

STEM education is included in education programs by many countries on a global scale. Pre-service teachers are also expected to apply STEM education in their future classrooms. The aim of the research was to determine how pre-service science teachers perceived STEM education, whether they adopted it or not, whether they thought of themselves as sufficient, and the environment and situations that affected their STEM experience. The understanding of the pre-service science teachers was tried to be determined before the theoretical STEM education, after the theoretical education and after the STEM application. The study group of the research consisted of a total of 66 pre-service teachers. Content analysis results of the interviews were carried out in three stages. It was found that there was no single STEM definition that pre-service science teachers agreed on. The training provided increased the STEM competency levels of pre-service science teachers. However, the majority of pre-service science teachers defined themselves as having intermediate competence in STEM education. Pre-service teachers adopt STEM education and believe that it will contribute to students. Pre-service science teachers had the most difficulty in disciplinary integration during the STEM theory and practice education. The most preferred model after both theoretical knowledge and application was the problem-based STEM model.
Keywords: content analysis, pre-service science teachers, STEM education, STEM understanding
UTILIZATION OF PROCESS DATA IN CHINA: EXPLORING STUDENTS’ PROBLEM-SOLVING STRATEGIES IN COMPUTER-BASED SCIENCE ASSESSMENT FEATURING INTERACTIVE TASKS
Authors: Zhao Pingping , Chang Chun-Yen , Shao Yueyang , Liu Zhi , Zhou Hao , Liu Jian
Published: October 2023

Students’ problem-solving strategies and the differences among strategy groups were explored by analyzing the process data collected during student interactions with computer-based science items. Data were gathered from 1516 eleventh-grade students from 4 schools in China. Analyses of the sequences of students’ response actions revealed that the students were divided into four strategy groups when designing experiments to solve scientific problems: the scientific and rigorous strategy (18.5%), scientific and less rigorous strategy (25.4%), incomplete strategy (31.5%), and chaotic strategy (24.6%). The heatmaps of response actions for each strategy and the frequencies of the most representative response sequences were further explored to understand the students’ detailed trajectories. The results showed that successful problem solvers were generally inclined to explore all possibilities of experimental combinations and design experiments scientifically and rigorously based on the relevant scientific principles. Moreover, the timestamps of response actions were explored to show that the students who adopted the scientific and rigorous strategy spent more time seeking solutions, suggesting that students may need sufficient time to solve complex and authentic scientific problems. The findings enrich the literature on using process data to address theoretical issues in educational assessment and provide students with individualized instructional needs for teachers to improve students’ scientific problem-solving competency.
Keywords: process data, scientific problem-solving, computer-based assessment, China
Compliance and clinical benefit of deferasirox granule and dispersible tablet formulation in pediatric patients with transfusional iron overload: in a randomized, open-label, multicenter, phase II study
Authors: Taher Ali T , Wali Yasser , Cruz Maria Cecilia , Charoenkwan Pimlak , Aydinok Yesim , Werner Olena , Govindaraju Sameera , Romen Fabian , Viprakasit Vip
Published: October 2023

CALYPSO (NCT02435212), a randomized, open-label, multicenter, phase 2 study evaluated the compliance, clinical benefits, and safety of deferasirox granules and dispersible tablets in pediatric patients with iron overload. Iron chelation therapy-naive and iron chelation therapy–pre-treated patients aged 2 to 0.5 mg/mg; 24.5% and 34.2%), upper respiratory tract infection (28.2% and 29.7%), and pyrexia (26.4% and 23.4%).
In iron chelation therapy-naive patients, mean compliance and change from baseline in serum ferritin with both deferasirox formulations were not significantly different. The safety profile was comparable between granule and dispersible tablets formulations, and was consistent with the general safety profile of deferasirox.
Factors associated with refractoriness or early progression after idecabtagene vicleucel in patients with relapsed/refractory multiple myeloma: U.S. Myeloma Immunotherapy Consortium real world experience
Authors: Hashmi Hamza , Hansen Doris K. , Peres Lauren C. , Puglianini Omar Castaneda , Freeman Ciara , De Avila Gabriel , Sidana Surbhi , Shune Leyla , Sborov Douglas W. , Davis James , Wagner Charlotte , Kocoglu Mehmet H. , Atrash Shebli , Voorhees Peter , Simmons Gary , Ferreri Christopher , Kalariya Nilesh , Anderson Larry D. , Afrough Aimaz , Dima Danai , Khouri Jack , McGuirk Joseph , Locke Fred , Baz Rachid , Patel Krina K. , Alsina Melissa
Published: October 2023

While response rates and survival outcomes have been very promising for idecabtagene vicleucel (ide-cel), a proportion of patients do not respond or relapse early after this B-cell maturation antigen (BCMA) targeted CAR T-cell therapy. Understanding the characteristics of these patients is important for patient selection and development of novel strategies to improve outcomes. We evaluated factors associated with early progression (progression or death due to myeloma ≤ 3 months after CAR T infusion) in patients treated with standard of care ide-cel at 11 US academic centers. Among 211 patients that received ide-cel, 43 patients had a progressive event ≤ 3 months of infusion. Patients with a history of extramedullary disease, prior BCMA targeted therapy, elevated ferritin at lymphodepletion, use of bridging therapy, Hispanic ethnicity, plasma cell leukemia and t(4;14) were more likely to progress ≤ 3 months of infusion (p < 0.05). Of these risk factors for early progression identified in univariate analyses, history of extramedullary disease, prior BCMA targeted therapy, elevated ferritin at lymphodepletion, plasma cell leukemia, and t(4;14) were associated with worse progression-free survival (PFS) in multivariable analysis. Presence of three or more of these factors had a significant negative impact on PFS (p < 0.001; median PFS for ≥ 3 factors, 3.2 months vs. 0 factors, 14.1 months). This study helps identify patients at high risk of early progression after CAR T who may benefit from specific interventions pre and post CAR T to improve outcomes.
Small myeloid subclones are present at diagnosis of multiple myeloma in patients who develop secondary myelodysplastic syndromes
Authors: Escure Guillaume , Fournier Elise , Saade Cynthia , Issa Lama Hasan Bou , Arib Inès , Tilmont Rémi , Gazeau Nicolas , Thiam Binta M. , Chovet Morgane , Delforge Maxime , Gower Nicolas , Fléchon Léa , Cavalieri Doriane , Chauvet Paul , Nudel Morgane , Goursaud Laure , Berthon Céline , Quesnel Bruno , Facon Thierry , Preudhomme Claude , Duployez Nicolas , Manier Salomon
Published: October 2023

Not available.
Machiavelli’s Republic: A Better Place to Be
Authors: Christopher Binetti
Published: October 2023

Machiavelli is an underappreciated figure. He is either viewed as an unprincipled, but very Italian figure or treated more fairly, but viewed as a generic European or even Anglicized. This article views Machiavelli as distinctly Italian and as an inheritor of the classical republicanism of Rome on one hand and Aristotle on the other. This article attempts both to explain the modern theory of republicanism and its ancient roots to a wider, more diverse audience and to present Macohiavelli as an Italian thinker, as opposed to as a European thinker. This project is both about ensuring that classical republican is available to persons from all cultures and backgrounds, but also de-Europeanize and de-Anglicize the cultural assumptions around Machiavelli. He is thus best understood as uniquely and irreducibly Italian and also part of a universal movement towards better government. At a time in which majoritarian democracies are out of control all over the world, the checks and balances inherent in classical republicanism serve both as a counterweight and also as a complement to modern democracy.
When the Factor of Crystallized Intelligence Can Be a Professionally “Undesirable” Personal Quality of Operators
Authors:   A.I. Burnazyan Federal Medical Biophysical Center, Moscow, Russia, Kosenkov A.A.
Published: October 2023

Purpose: To discuss the case of oppositely directed influences of the indicators of crystallized and fluid intelligence in the decisive rule designed to predict the professional success of the nuclear power plants (NPPs) operators. Material and methods: This paper analyzes the results of psychodiagnostic examinations of operators of main control rooms (MCR) of NPPs that functioned under normal conditions. All individuals were administered the J. Raven’s “Progressive matrices”, the Russian language adaptation of the Minnesota Multiphasic Personality Inventory (MMPI) and the Sixteen Personality Factor Questionnaire (16PF, form A). A cross-expert review using the ranking method revealed two groups of operators with relatively higher and lower levels of professional success. The method of canonical correlation analysis has been used to obtain the best linear discriminator for predicting the professional success of MCR operators based on indicators of psychodiagnostic tests. Results: Based on the results of the expert assessment, two groups of operators with the highest and lowest professional success were identified. Decisive rule were obtained that make it possible to predict the professional success of operators based on a system of signs (values of the psychodiagnostic tests scales multiplied by coefficients) after the data processing using canonical correlation analysis. Unexpected result was that the high values of 16PF factor «B» turned out to be «undesirable» for the prediction of professional success, that is, these values increased the probability of assigning the operator to the group of the lowest successful specialists. Conclusion: Factor «B» of 16PF was considered as a tool for assessing predominantly crystallized intelligence, and the Raven’s test – for the fluid one. At the same time, there are no methods that allow measuring these indicators in their purest form. Taking this fact into account, the author believes that the true role of factor B in the decisive rule did not reflect the undesirability of advanced crystallized intelligence among MCR operators. It is most likely that its opposition to the «desirable» indicator (the number of correctly solved tasks of the Raven’s test) made it possible to single out the role of fluid intelligence (or some of its lower-level aspects) as a professionally important quality for the particular operator activity.
SPECT/CT with 99mTc-Technetryl in Staging, Planning of External Radiotherapy and Follow-up in Lung Cancer: a Clinical Case and Case – Addressed Review of Literature
Authors:   E.N. Meshalkin National Medical Research Center, Novosibirsk, Russia, Minin S.M. , Anashbayev Zh.Zh. ,   E.N. Meshalkin National Medical Research Center, Novosibirsk, Russia, Samoylova E.A. ,   E.N. Meshalkin National Medical Research Center, Novosibirsk, Russia, Zheravin A.A. ,   E.N. Meshalkin National Medical Research Center, Novosibirsk, Russia, Ussov W.Yu. ,   E.N. Meshalkin National Medical Research Center, Novosibirsk, Russia, Krasilnikov S.E. ,   E.N. Meshalkin National Medical Research Center, Novosibirsk, Russia, Cherniavsky A.M. ,   E.N. Meshalkin National Medical Research Center, Novosibirsk, Russia
Published: October 2023

The case of a patient with newly diagnosed peripheral cancer of the right lung, involving the pleura, in whom the local extent of the process initially detected by X-ray CT was significantly extended from the data of the SPECT with 99mTc-technetryl. In particular, with SPECT/CT before the start of radiation therapy (RT), involved lymph nodes were detected both in the lower edge of the root of the right lung, and in paraaortic and paratracheal location. The SPECT/CT with 99mTc-technetryl was carried out with dual-detector gamma-camera GE Discovery NM/CT 670 DR (GE Medical) in a quantitative mode, with calibration and calculation of indexes of standardized uptake values (SUV) and % uptake of the administered activity by the primary tumor and metastatically involved lymph nodes. The values of the volume of tumor tissue were, respectively, for the tumor and the largest proximal metastatically involved lymph node 154.2 cm3 and 12.9 cm3, % of the activity absorbed by the tumor tissue − 0.498 and 0.030 %, and SVP ‒ 2.19 and 2.5.With subsequent external radiation therapy (in total 40 Gy, 2 Gy 5−6 times a week) the irradiation fields were planned in such a way that all affected lymph nodes were within their borders. A control SPECT/CT study carried out immediately after the RT showed a decrease in the volume of tumor tissue in the primary node down to 58 cm3, % of the activity absorbed by the tumor tissue to 0.090 %, and SVP ‒ to 1.15. Reliable imaging of lymph nodes after LT was not observed. After 6.5 months, no evidencies for relapse or continued tumor growth were detected with a control X-ray CT performed on an outpatient visit with contrast enhancement. Thus, SPECT/CT with 99mTc-technetryl in lung cancer is a vital method for clarifying the diagnosis and assessment of the extent of the tumor process, as well as monitoring the patient. A broad inter-center assessment of abilities of the SPECT/CT with 99mTc-technetryl in lung cancer is advisable, especially when planning RT.
Análisis de la Gestión de Riesgos: Caso de una empresa mediana del sector comercial en Guadalajara
Authors: Aguilar Pérez Pedro , Cruz Covarrubias Lucila Patricia
Published: October 2023

El objetivo de esta investigación fue analizar el panorama de la gestión de riesgos en una empresa mediana de la ciudad de Guadalajara y evidenciar el conocimiento y la aplicación de la gestión de riesgos empresariales. El método de estudio asume un enfoque cualitativo con un procedimiento de estudio de caso, también se empleó la entrevista semiestructurada aplicada a cinco directivos de la organización objeto de estudio; asimismo, se entrevistaron a dos expertos externos en el área de riesgos. Los resultados muestran que la empresa realiza acciones de control interno y de cumplimiento legal para el logro de sus objetivos; sin embargo, manifiestan desconocer una metodología como la ISO 31000; y existe confusión entre concepto de riesgos y control interno, hecho que se demuestra en la concentración de gestión en algunas áreas y con escasa cultura enfocada a riesgos. En conclusión, la empresa realiza prácticas de mejora administrativa, permitiendo corregir algunas operaciones e incurren en no desarrollar competencias significativas para mitigar los riegos de la compañía.Palabras Clave: gestión de riesgos, mejora de procesos, prácticas empresariales, riesgos.

Abstracthe objective of the research was to analyze the panorama of risk management in a medium-sized company in the city of Guadala- jara. Likewise, it is intended to demonstrate the knowledge and application of business risk management. The study method assumes a qualitative approach, with a case study procedure, a semi-structured interview was used, conducted with five managers of the organization under study, and two external experts in the risk area were also inter- viewed. The results show that the company carries out internal control and legal compliance actions to achieve its objectives; they state that they are unaware of a methodology such as ISO 31000; there is con- fusion between the concept of risks and internal control, a fact that is demonstrated in the concentration of management in some areas and with little culture focused on risks. Conclusion: the company carries out administrative improvement practices allowing to correct some operations; they incur in not developing significant competences to mitigate the company’s risks.

Keywords: risk management, process improvement, business practices, risks
BRING ON THE LIGHT: REDUCTION OF THE CORPORATE SHADOW ECONOMY BY TAX REFORM
Authors: Giedraitis Vincentas Rolandas , Stavytskyy Andriy , Kharlamova Ganna , Ulvidienė Erstida
Published: October 2023

Background: Our preliminary research shows that tax reform can have a meaningful impact in reducing the corporate shadow economy of a society. Countries are constantly applying lower tax rates to attract large businesses to their territory. They are also trying to improve tax collection efficiency in their jurisdiction area. We study the relationship between the Baltic countries' tax systems and the shadow economy level within their respective economies. Our research examines how economic growth can reduce the corporate shadow economy due to changes in tax collections.
Methods: Based on quarterly data from 2002-2022, a panel regression was chosen for the analysis, which allows for determining the impact of each specific tax on the level of the shadow economy separately, considering all three samples as one synergistic system.
Results and Conclusions: Thus far, we find that for all types of taxes, the models have the same structure, which allows for comparing the impact of gross domestic product on tax collections both in the short and long term. Our analysis showed that the effective income tax rate growth increases the shadow economy; that is, the country's citizens attempt to move into the shadows. At the same time, the growth of the effective corporate income tax rate, on the contrary, reduces the level of the shadow economy. A positive increase in the effective VAT rate also contributes to the growth of the shadow economy. The long-term effect for general taxes is almost 19% higher than the growth of the tax base. Thus, as to the Lithuanian economy, for example, it has a tendency for a reduction of the shadow economy, which means that there are significant opportunities for further improvement.
PLATFORM EMPLOYMENT AND THE OBLIGATION TO CONCLUDE AN EMPLOYMENT CONTRACT IN THE REPUBLIC OF KAZAKHSTAN: ISSUES OF THEORY AND PRACTICE
Authors: Aigerim Zhumabayeva , Nurmagambetov Amanzhol
Published: October 2023

Background. The article is devoted to the main issues of legal regulation of platform employment in the Republic of Kazakhstan. The authors gradually considered the issues of the overarching concept of platform employment, its national legal regulation, the correlation of platform employment with labour relations, and the necessity of mandating Internet platform operators to conclude employment contracts with individuals providing their services.
Methods: In the process of analysing the current Kazakhstani labour and related legislation, national and international judicial practice, the authors came to the conclusion that the Social Code adopted in 2023 and the Law ‘On Online Platforms and Online Advertising’ separate the concept of an Internet platform and online -platforms. Internet platforms are so-called work platforms that specialise in mediating the provision of services and work performance. The authors identified several problems that arose with adopting the Social Code. In particular, the authors do not share the legislator’s idea on the need for civil law regulation of relations in platform employment between the contractor and the Internet platform operator. The authors propose a targeted approach to determining the nature of the legal regulation of platform employment. Labour activity using Internet platforms, if it has signs of hidden labour relations specified in the ILO recommendations, should be regulated by labour legislation. Otherwise, the trend towards precarisation of the Kazakh labour society will inevitably strengthen.
Results and conclusions: Based on the statistical data analysis, the authors concluded that more and more people with higher or professional education adjoin the number of self-employed, hence the performers of platform employment. The data suggest that precarisation in the Republic of Kazakhstan is rapidly spreading among the underclass labourers and the relatively prosperous and promising able-bodied population of the country.
Potential of Cassava Peel as Cr Metal Biosorbent in Laboratory COD Waste
Authors: Rachman Farhan Fatur , Syahputri Yulian , Sutanto Sutanto
Published: October 2023

Cassava peel is an agricultural residual waste that can be found from industrial processing in Indonesia. Cassava peel contains cellulose which can be used as a biosorbent. The aim of this study was to optimize the adsorption of cassava peel waste on chromium metal ions and then to determine the adsorption capacity and adsorption constant values of the Langmuir model and the Freundlich model. The research was divided into four stages, namely manufacture, optimization conditions, maximum capacity, and application to waste. Optimization conditions for weight ratio, optimum concentration, pH, and contact time. Determination of chromium content, standard series, and testing using the APHA method SSA ed. 23rd 3030 D 3111 B, 2017 at a wavelength of 357.78 nm. Determination of adsorption isotherms of Langmuir and Freundlich models. The optimum condition results at a weight ratio of 1 gram in 10 ml of solution, a concentration of 10 ppm, pH 2, and a contact time of 180 minutes. The adsorption capacity is 0.10216 mg Cr/gram cassava peel biosorbent. Application to chrome contamination laboratory waste obtained an adsorbed concentration of 20.681 ppm. In the Langmuir and Freundlich isothermal model, the R2 value is 0.9668 and 0.9985, the n value is 0.73964.
Antibacterial Activity of Ocimum citriodorum Leave Extracts Against Shigella dysenteriae
Authors: Komala Oom , Utami Novi Fajar , Darmawan Saraswati
Published: October 2023

Dysentry is a disease caused by infection of Shigella dysenteriae (S. dysenteriae). This type of acute diarrhea characterized by the liquid stool mixed with blood and mucus caused by these bacteria. Ocimum citriodorum (O. citriodorum) leaves contain various chemical compounds that can inhibit the growth of diarrhea-causing bacteria. This study aims to determine the antibacterial activity of O. citriodorum leaves extracts obtained from graded extraction method against S. dysenteriae. The O. citriodorum leaves were extracted using ethanol, ethyl acetate, and n-hexane solvents sequentially. The Minimum Inhibitory Concentration (MIC) test was carried out using dilution method. The positive control used was 10 ppm ciprofloxacin (0.002%). The results showed that the extract of n-hexane, ethyl acetate, and ethanol of O. citriodorum leaves all three have antibacterial activity against S. dysenteriae with the same MIC value of 15%. The most effective MIC of n-hexane, ethyl acetate, and ethanol extract of O. citriodorum leaves was found at a concentration of 15% zone inhinbition with ethanol extract of O. citriodorum leaves
Chatbot PTIPD Customer Care Center Service using Dialogfow
Authors: Ndruru Arlan Joliansa , Fikry Muhammad , - Yusra
Published: October 2023

Chatbot research is a unique innovation in the development of Artificial Intelli- gence and has promising prospects in the field of Education. One form of information service available at the university is the Customer Care Center (C3) PTIPD UIN Suska Riau, which is responsible for handling problems submitted by students. However, with so many questions or problems submitted to the PTIPD Customer Care Center, it is difficult for the PTIPD Cus- tomer Care Center to respond to student questions submitted, the service becomes ineffective and the response to the answers to the problems submitted becomes late. To overcome this problem, chatbot development was carried out for PTIPD UIN Suska Riau Customer Care Center Services using Dialogflow to improve services and overcome existing problems. Di- alogflow as conversation development platform that uses natural language processing (NLP) to understand and interpret user intent in conversations. Through User Acceptance Test (UAT) testing, the chatbot managed to achieve an acceptance rate of 84% overall. This shows that users, in this case, students respond positively to the use of chatbots in PTIPD Customer Care Center services. In addition, Usability Testing was also conducted to evaluate the level of usability of the chatbot. Based on this test, the chatbot achieved a score of 76, which indicates a good level of usability in interaction with users. The test results illustrate that the chatbot at the Customer Care Center PTIPD UIN Suska Riau has provided a positive user experience.
On the velocities addition relativistic equation
Authors: Scano Pier Sandro
Published: October 2023

Is esamined the current status of the theory of special relativity. The article contains an updated overview of the theoretical research and recent experimental evidence. Chapters I-II highlight the experimental foundations of special relativity and the consequent domain of applicability. Chapter III addresses the issues open of the level of theory and matematical formalism. In chapter IV the conclusions about the equation of addition of velocities, the absence of confirmed extablished experiments for lenght contraction , as opposed to time dilation, the problems of the 4-dimensional formalism, i.e., the theorie of spacetime. Special relativity represents a theory with verified experimental confirmation, but nevertheless lacks sufficient elements to assume it as a complete and definitive description of the spacetime relationships.
Applied Machine Learning for Short-Term Electric Load Forecasting in Cities - A Case Study of Eskilstuna, Sweden
Authors: Netzell Pontus , Kazmi Hussain , Kyprianidis Konstantinos
Published: October 2023

With the growing demand, electrification, and renewable proliferation, the necessity of being able to forecast future demand in combination with flexible energy usage is tangible. Distribution network operators often have a power capacity limit agreed with the regional grid, and economic penalties await if crossed. This paper investigates how cities could deal with these issues using data-driven approaches. Hierarchical electric load data is analyzed and modeled using Multiple Linear Regression. Key calendar variables holidays, industry vacation, ”Hour of day” and ”Day of week” are identified alongside the meteorological heating-, and cooling degree hours, global irradiance, and wind speed. This inexpensive algorithm outperforms the benchmark ”weekly Naïve” with a relative Root Mean Squared Error of 35% for the year-long rolling origin evaluation. Learnings from the data exploration and modeling are then used to evaluate the AI-based model Light Gradient Boosting Machine. Using similar explanatory variables for this expensive algorithm results in a relative error of 45%, although it outperforms the previous one during the summer. The models have varying strengths and weaknesses and could advantageously be combined into an ensemble model for improving accuracy. Incorporating detailed knowledge of local renewable electricity production in combination with hierarchical forecasting could further increase accuracy. With domain knowledge and statistical analysis, it is possible to create robust load forecasts with acceptable accuracy using easily available machine-learning libraries. Both models have good potential to be used as input to economic optimization and load shifting.
Optimal indoor temperature flexibility for thermal peak shaving in buildings connected to the district heating network
Authors: Cederbladh Mathilda , Dahlberg August , Vouros Stavros , Kyprianidis Konstantinos , Saletti Costanza , Morini Mirko
Published: October 2023

Buildings are currently non optimally controlled, using a weather compensation controller that depends only on external temperature. A rich amount of real-time data is available and can be used for better control. This work is focused on developing a general and dynamic model for utilizing the building as an energy storage for a peak-shaving control strategy.A dynamic grey-box model is developed using industry standard operators’ data from a multifamily building, Building A, located in Västerås, Sweden. The training period is set to 408 hours, and the prediction horizon to 48 hours. The model is verified in 4 steps: prediction ability on the historic data, parametric verification on the time constant, simulation of heat supply separated from the historic data and model generality by implementing the model on a second multifamily building, Building B. The modelling errors over a two-month simulated period are 8% for Building A and 9% for Building B. To demonstrate the utilization possibilities, an optimizer is constructed to evaluate a peak shaving control strategy. Different flexibilities for the indoor temperature have been examined yielding heat load peak shaving between 30 to 45%. Flexibility paves the way for improvement in pricing models for the heating sector. This work demonstrates the potential for utilizing building heat storage capacity to reduce peak consumption and costs.
Process Simulation and Cost Optimization of a Gas based Power Plant including amine based CO2 Capture
Authors: Øi Lars Erik , Amiri Esmaeil Aboukazempour
Published: October 2023

CO2 capture from gas turbine exhaust gas using heat from the power generation cycle is a possibility for CO2 emission reduction from natural gas-based power plants. A simplified power plant was simulated in Aspen HYSYS with a compressor, a combustion chamber, a turbine, a steam circuit with a steam heater, a high-pressure steam turbine, a low-pressure steam turbine, a steam condenser, and a circulating pump. CO2 capture was simulated with an absorption column, a rich amine pump, a lean/rich amine heat exchanger, a desorber with a reboiler and condenser, a lean pump and an amine cooler. The equipment cost was obtained from Aspen In-plant Cost Estimator, and an enhanced detailed factor method was used to estimate the total investment. A base case with combustion at 30 bar, ΔTMIN of 10 °C, and 10 stages (meters of absorber packing) was simulated, dimensioned, and cost estimated. In earlier works, optimum parameters have been found by minimizing the cost of CO2 capture. In this work, optimum was defined as the maximum profit for a combined process with 85 % capture efficiency. Optimized parameters were calculated to 25 bar for the combustion pressure, 13 °C for the minimum temperature approach in the lean/rich amine heat exchanger, and 10-meter packing height in the absorption column. These values are comparable to values in literature.
Insight into the thermodynamic model for reforming of methane over nickel catalyst
Authors: Rakhi Rakhi , Giri Binod R. , Günther Vivien , Mauss Fabian
Published: October 2023

The reforming of light hydrocarbons to produce synthesis gas, H2 and CO, is an important intermediate for manufacturing valuable basic chemicals and synthesis fuels. In order to understand these reforming processes better, elementary step reaction mechanisms are developed. In the available literature, the surface reaction mechanisms are usually achieved with the help of reaction kinetic parameters without using the thermochemistry of the species referred to kinetic models due to the unavailability of the thermochemistry of the intermediate species involved in the multi-step reaction mechanism. In this work, investigations are made to obtain the thermochemistry of the intermediate species to establish thermodynamic equilibrium in order to develop thermodynamic model for steam reforming of methane over nickel. The thermochemistry of the surface bound species is taken from different sources available in the literature and after that a detailed sensitivity analysis is performed to match the results with experiments. The simulation set up is adapted from the literature experiments given in [1]. The results produced with the one-dimensional tool using the thermodynamic model developed in the present investigation consisting of 21 reversible reactions are compared with the kinetic scheme with 42 irreversible reactions from reference simulation along with their experimental results. Both the models show some major differences in the reaction pathways which provides a useful insight into the key rate determining steps and needs further investigations.
Dynamic Modelling and Part-Load Behavior of a Brayton Heat Pump
Authors: Pettinari Matteo , Frate Guido Francesco , Kyprianidis Konstantinos , Ferrari Lorenzo
Published: October 2023

Among the environmental-friendly technologies recently proposed in the literature, high-temperature heat pumps represent a promising solution to foster the complete penetration of renewables within the power grid. Such systems may be based on closed Brayton cycles and leverage many existing components. As they are meant to provide high-temperature heat while using renewable electricity, their potential field of application ranges from industrial heating to energy storage. Several variants are currently under development to assess the feasibility of such systems in providing flexibility to the electricity grid. To do so, they need to operate in part-load conditions and quickly react when the load must be adjusted. In this regard, this study investigates the transient capabilities of Brayton heat pump technology. To this extent, a detailed transient model of a novel prototype proposed in the literature is presented, accounting for controls, thermal inertia and volume dynamics related to heat exchangers and piping. Furthermore, the model is used to assess the transient performance of the system in response to sudden load variations, which is achieved by adapting the turbomachinery operating velocities. Results show that the system can safely operate in part-load conditions with regulation times compatible with industrial needs.
A Semi-Automatic Translator from System Dynamics to Modelica with Application to Socio-Bio-Physical Systems
Authors: Tinnerholm John , Zapatero Mariano , Pop Adrian , Fritzson Peter , Castro Rodrigo
Published: October 2023

System Dynamics is a modelling paradigm that has been applied to a wide range of systems, from economic to physical and from managerial to ecological. The main strength of the paradigm is its ease of use. A System Dynamics modeller does not need to focus on equations; instead, models are expressed in terms of stocks and flows. Modelica, on the other hand, is an equation-based modelling language capable of multi-domain modelling using equations. It gives the user more freedom but requires more mathematical focus and skills. Therefore, a unification of equation-based modelling and the System Dynamics paradigm is seen as highly beneficial. Advantages include the ability for System Dynamics modellers to use the tools available in the Modelica ecosystem. Furthermore, it allows the integration of System Dynamics models into Modelica models. To achieve this goal, we developed an XMILE-to-Modelica translator that maps System Dynamics models represented in the XMILE standard exchange format to Modelica models. We also applied a Modelica-to-Julia translator to demonstrate the generality of the approach.We translated several models to test the correctness of the translator. In particular, the Earth System Climate Interpretable Model (ESCIMO) was translated from its original version in the Vensim toolkit into the OpenModelica toolkit, and a correct validation was obtained by comparing simulation results between simulators. Our work improves tool interoperability and further demonstrates the feasibility of using Modelica as a unified, standard language to integrate models created using System Dynamics, including large and complex socio-biophysical systems.
Computer controlled expansion of equine cord blood mesenchymal stromal cells on microcarriers in 3 L vertical-wheel® bioreactors
Authors: Roberts E. L. , Abraham B. D. , Dang T. , Gysel E. , Mehrpouyan S. , Alizadeh A. H. , Koch T. G. , Kallos M. S.
Published: October 2023

Mesenchymal stromal cells (MSCs) are an ideal cell source for allogenic cell therapy due to their immunomodulatory and differentiation properties. Equine MSCs (eMSCs) have been found to be a promising treatment for equine joint injuries including meniscal injuries, cartilage degradation, and osteoarthritis. Although the use of eMSCs has shown efficacy in preliminary studies, challenges associated with biomanufacturing remain. To achieve the required cell numbers for clinical application, bioreactor-based processes are required. Initial studies have shown that eMSCs can be cultivated in microcarrier-based, stirred suspension bioreactor culture at the laboratory 0.1 L scale using a Vertical-Wheel® (VW) bioreactor. However, investigations regarding scale up of these processes to the required biomanufacturing scales are required. This study investigated the scale-up of a equine cord blood MSC (eCB-MSC) bioprocess in VW bioreactors at three scales. This included scale-up from the 0.1–0.5 L bioreactor, scale-up from static culture to the 3 L computer-controlled bioreactor, and scale-up into the 3 L computer-controlled bioreactor using a mock clinical trial process. Results from the various scale-up experiments demonstrated similar cell expansion at the various tested scales. The 3 L computer-controlled system resulted in a final cell densities of 1.5 × 105 cells/cm2 on average, achieving 1.5 × 109 harvested cells. Biological testing of the cells showed that cell phenotype and functionality were maintained after scale-up. These findings demonstrate the scalability of an eCB-MSC bioprocess using microcarriers in VW bioreactors to achieve clinically relevant cell numbers, a critical step to translate MSC treatments from research to clinical applications. This study also represents the first known published study expanding any cell type in the 3 L VW bioreactor.
Advancing bovine in vitro fertilization through 3D printing: the effect of the 3D printed materials
Authors: Belda-Perez Ramses , Heras Sonia , Cimini Costanza , Romero-Aguirregomezcorta Jon , Valbonetti Luca , Colosimo Alessia , Colosimo Bianca Maria , Santoni Silvia , Barboni Barbara , Bernabò Nicola , Coy Pilar
Published: October 2023

Nowadays there is an increasing demand for assisted reproductive technologies due to the growth of infertility problems. Naturally, fertilization occurs in the oviduct, where the oviductal epithelial cells (OECs) secrete many molecules that affect the embryo’s metabolism and protect it from oxidative stress. When the OECs are grown in 3D culture systems, they maintain a great part of their functional characteristics, making them an excellent model for in vitro fertilization (IVF) studies. In this work, we aimed to evaluate the suitability of different 3D-printing processes in conjunction with the corresponding set of commercially available biomaterials: extrusion-based processing using polylactic acid (PLA) and polycaprolactone (PCL) and stereolithography or digital-light processing using polyethylene-glycol-diacrylate (PEGDA) with different stiffness (PEGDA500, PEGDA200, PEGDA PhotoInk). All the 3D-printed scaffolds were used to support IVF process in a bovine embryo assay. Following fertilization, embryo development and quality were assessed in terms of cleavage, blastocyst rate at days 7 and 8, total cell number (TCN), inner cell mass/trophectoderm ratio (ICN/TE), and apoptotic cell ratio (ACR). We found a detrimental effect on cleavage and blastocyst rates when the IVF was performed on any medium conditioned by most of the materials available for digital-light processing (PEGDA200, PEGDA500). The observed negative effect could be possibly due to some leaked compound used to print and stabilize the scaffolds, which was not so evident however with PEGDA PhotoInk. On the other hand, all the extrusion-based processable materials did not cause any detrimental effect on cleavage or blastocyst rates. The principal component analysis reveals that embryos produced in presence of 3D-printed scaffolds produced via extrusion exhibit the highest similarity with the control embryos considering cleavage, blastocyst rates, TCN, ICN/TE and ACR per embryo. Conversely, all the photo-cross linkable materials or medium conditioned by PLA, lead to the highest dissimilarities. Since the use of PCL scaffolds, as well as its conditioned medium, bring to embryos that are more similar to the control group. Our results suggest that extrusion-based 3D printing of PCL could be the best option to be used for new IVF devices, possibly including the support of OECs, to enhance bovine embryo development.