bluuebunny/crossref_metadata_2025 huggingface dataset:
Ligaplants -A future endeavour
Authors: Melath Anil , Raveendran Arjun Machingal , Stephenraj Sindhuja , Prakash N. , Sayoojya V. , Nazir Shakoufa
Published: October 2024

Implant dentistry has been transformed by the Introduction of periodontal tissue engineering. Based on the modality, ligaplants have been recently introduced to overcome the shortcomings of conventional implants. The majority of the studies related to the ligaplants, done on animals have shown successful results but still more achievable and practical way of procuring the periodontal ligament attached implants needs to be introduced. Also, more human studies need to be done to evaluate the successful outcome of this strategy.
Effects of oral health problems in athletic performance
Authors: Soileau Kristi M. , Le Anthony , Bresky Ilana
Published: October 2024

The study was a review of articles relating to the effects of oral disease as they create potential challenges in overall health and performance, especially in elite athletes. The authors searched articles on sports dentistry, elite athleticism, the prevalence of oral diseases among athletes, as well as physiological debilitation on movement secondary to oral health issues in general. Data were then categorized into sections related to varying types of oral diseases, and their effects on performance both in competitive sports as well as in day-to-day functioning. The use of protective equipment and salivary diagnostics for utilization in the prevention of disease were also included in the review. A total of 76 articles were selected for use in the paper. It is well-documented that common oral conditions such as caries, periodontal diseases, dental erosion, malocclusion, temporomandibular joint disorders, stress and immune suppression, poor nutrition, and injuries of various types can have deleterious effects on athleticism and can create untoward physiological challenges. Protective sports equipment and the care of such is also important to consider. Athletes should know the risks associated with activities particular to their various fields of interest and need to direct adequate attention to their personal oral health status. Negative effects of poor oral health on physical fitness, performance, and cognitive function have been noted in many scholarly articles, yet the majority of athletes have limited education and training in such matters. Maintaining good fitness also requires striving for optimal, oral health, which includes proper professional diagnosis, treatment, and monitoring.
Presence of radix entomolaris in primary mandibular first molars: A review of rare entity
Authors: Macharla Srilekha , Dasari Nikhitha Raj , Karre Anusha , Anusha Challagulla
Published: October 2024

Numerous developmental anomalies with respect to crown and root are commonly seen in permanent dentition and while rarely in the primary dentition. Radix entomolaris (RE), an extra root seen on the distolingual aspect of mandibular molars, is one such aberration found. The presence of extra root in primary mandibular first molars is of extreme rarity and such two reports its significance had been discussed. Two children of 5- and 7 years old reported to the pediatric and preventive dentistry department with a chief complaint of pain in the right and left mandibular back teeth region, respectively. A diagnosis of chronic irreversible pulpitis was made in both cases with the accidental appraisal of RE in both the primary first molars on intraoral periapical radiographs. Standard pulpectomy was performed in both cases. Pediatric dentists as well as clinicians should update regarding the abnormal morphologies of primary molars and its diagnostic including treatment strategies.
Nonsurgical periodontal therapy
Authors: Melath Anil , Raveendran Arjun Machingal , Kelotte Deepith , Priya K. Anurragha , Anuja R.
Published: October 2024

Nonsurgical periodontal therapy (NSPT) aims to eliminate both living bacteria in the microbial film and calcified biofilm microorganisms from the tooth and adjacent soft tissues. It has traditionally been carried out using hand and powered instruments; it is less invasive, more cost-effective, and easily applied in different clinical settings. It generally includes scaling, root planing, antimicrobial therapy, laser therapy, and gum line therapy. Hence, NSPT is the gold standard against which other treatment options are compared.
Mixed‐mode SNN crossbar array with embedded dummy switch and mid‐node pre‐charge scheme
Authors: Oh Kwang‐Il , Kim Hyuk , Kang Taewook , Kim Sung‐Eun , Lee Jae‐Jin , Yang Byung‐Do
Published: October 2024

This paper presents a membrane computation error‐minimized mixed‐mode spiking neural network (SNN) crossbar array. Our approach involves implementing an embedded dummy switch scheme and a mid‐node pre‐charge scheme to construct a high‐precision current‐mode synapse. We effectively suppressed charge sharing between membrane capacitors and the parasitic capacitance of synapses that results in membrane computation error. A 400 × 20 SNN crossbar prototype chip is fabricated via a 28‐nm FDSOI CMOS process, and 20 MNIST patterns with their sizes reduced to 20 × 20 pixels are successfully recognized under 411 μW of power consumed. Moreover, the peak‐to‐peak deviation of the normalized output spike count measured from the 21 fabricated SNN prototype chips is within 16.5% from the ideal value, including sample‐wise random variations.
Quantum electrodynamical formulation of photochemical acid generation and its implications on optical lithography
Authors: Lee Seungjin
Published: October 2024

The photochemical acid generation is refined from the first principles of quantum electrodynamics. First, we briefly review the formulation of the quantum theory of light based on the quantum electrodynamics framework to establish the probability of acid generation at a given spacetime point. The quantum mechanical acid generation is then combined with the deprotection mechanism to obtain a probabilistic description of the deprotection density directly related to feature formation in a photoresist. A statistical analysis of the random deprotection density is presented to reveal the leading characteristics of stochastic feature formation.
XEM: Tensor accelerator for AB21 supercomputing artificial intelligence processor
Authors: Jeon Won , Lee Mi Young , Lee Joo Hyun , Lyuh Chun‐Gi
Published: October 2024

As computing systems become increasingly larger, high‐performance computing (HPC) is gaining importance. In particular, as hyperscale artificial intelligence (AI) applications, such as large language models emerge, HPC has become important even in the field of AI. Important operations in hyperscale AI and HPC are mainly linear algebraic operations based on tensors. An AB21 supercomputing AI processor has been proposed to accelerate such applications. This study proposes a XEM accelerator to accelerate linear algebraic operations in an AB21 processor effectively. The XEM accelerator has outer product‐based parallel floating‐point units that can efficiently process tensor operations. We provide hardware details of the XEM architecture and introduce new instructions for controlling the XEM accelerator. Additionally, hardware characteristic analyses based on chip fabrication and simulator‐based functional verification are conducted. In the future, the performance and functionalities of the XEM accelerator will be verified using an AB21 processor.
Assessing ChatGPT’s impact on curriculum outcomes and Entrustable Professional Activities (EPAs) during Advanced Pharmacy Practice Experiences (APPEs)
Authors: Goldman Deanna , Ashour Habiba , Zheng Mandy , Bradley Nicole , Ng Kimberly
Published: October 2024

Background: Chat Generative Pre-trained Transformer (ChatGPT) use in higher education has been controversial. The purpose of this study was to evaluate the impact of ChatGPT on pharmacy student achievement of educational outcomes and entrustable professional activities, as outlined by the American Association of Colleges of Pharmacy (AACP), during Advanced Pharmacy Practice Experiences (APPEs).
Methods: A 20-question electronic survey was distributed to pharmacy students in the Class of 2023 and 2024. The survey evaluated the impact of ChatGPT on educational outcomes and student perceptions of the technology. Results were analysed using descriptive statistics.
Results: A total of 69 students participated in the survey. Among them, 44% (17/39) used ChatGPT during their APPE rotations. Of those, 82% (14/17) of students agreed or strongly agreed that ChatGPT helped them find, analyse, and integrate foundational knowledge of medications. Similarly, 82% (14/17) agreed or strongly agreed that ChatGPT positively impacted their approach to work and research habits. Additionally, 89% (15/17) agreed or strongly agreed that they will use ChatGPT on future APPEs and in professional practice.
Conclusion: The use of ChatGPT by pharmacy students during their APPE rotations demonstrates a potential benefit in student achievement of educational outcomes across all three domains during APPEs.
Posterior cranial vault distraction osteogenesis: a literature review
Authors: Rodrigues Aline Rabelo , Lobo Izabella Rocha , Da Silva ⁠Sillas Bezerra , De Freitas Mariana Tainá Oliveira , Gomes Monique Benemérita Vilela , De Oliveira Ricardo Santos , Ballestero Matheus
Published: October 2024

Introduction:Craniosynostosis is a congenital condition where one or more cranial sutures close prematurely, limiting skull growth and causing cranial deformities. Posterior cranial vault distraction (PCVD) is used to relieve intracranial pressure and improve cranial aesthetics. Its incidence is about 1 in 2000–2500 live births.
Methods:This systematic review followed PRISMA guidelines. We searched PubMed, Scielo, and Lilacs for studies on PCVD in craniosynostosis, focusing on success, morbidity, and mortality. Six articles were included in the final review. Data were extracted and risk of bias was assessed using the ROBINS-I tool.
Results:The included studies reported significant increases in intracranial volume (144 mL to 281 mL) post-PCVD. Most patients showed stable results without recurrence. Complications included wound infection (29%) and cerebrospinal fluid leaks, though few required re-operations. PCVD improved intracranial pressure symptoms in most cases.
Conclusion:PCVD is an effective technique for treating craniosynostosis, increasing intracranial volume and improving symptoms of intracranial hypertension. Despite some complications, it remains a reliable and stable alternative for cranial expansion.
IMPACT OF ANTIHYPERTENSIVE DRUGS ON C REACTIVE PROTEIN (HS-CRP) AND NEUTROPHIL LYMPHOCYTE RATIO (NLR)
Authors: Salem Huda Ahmed , Mahmood Samira Abdulla , Ali Khaled Saeed
Published: October 2024

Many studies showed the association between inflammation and Hypertension. Inflammatory markers may highlight the state of inflammation in hypertensive patients. This study aimed to investigate impact of antihypertensive drugs on high sensitive C-reactive protein (hsCRP) and neutrophil lymphocyte ratio (NLR). A comparative cross sectional study was conducted on 86 hypertensive patients attending cardiology outpatient clinic in Al-Gamhuoria Modern General Hospital, Aden, in the period from October to December 2023. Participants were divided into three groups: patients treated with mono-therapy from inhibitors of renin angiotensin aldosterone system (RAASI), patients treated with mono-therapy antihypertensive not acting on RAAS (NRAASI) and patients treed with combination of them (drug combination). Data on Age, Sex, BP level, BMI, duration of hypertension (HTN), family history of HTN, and medications used were collected. Blood samples for measuring HsCRP, neutrophils, lymphocytes were drawn. Descriptive statics and chi-square tests were used for data analysis. Almost equivalent distribution for males and females between groups, with a large proportion of the patients within each group laid in the age group 35-55 years. The median values of hypertension duration were 36, 48, and 54 months for RAASIs, NRAASIs and drug combination group, respectively. The target BP was obtained by 46.9% 45.5% and 50% of patients treated with RAASIs, NRAASIs and drug combination respectively. There was a statistically significant difference between SBP and DBP in patients with controlled BP and those with uncontrolled SBP levels and treated by different drug regimens (P=0.000 for each Bp level). There were significant differences between values of hs-CRP of patients with controlled (P=0.000) or uncontrolled (P=0.046) BP and treated with different modalities. The median differences in NLR between the groups were statistically significant; including groups of all patients P=.032, of patients having controlled BP P=0.014 as well as uncontrolled BP P=0.038. Comparing the uncontrolled of BP of the three groups we found the highest prevalence (9.3%)of patients with uncontrolled BP and had the lower level hsCRP (≤3mg /l) was in RAASIs group, while those with higher prevalence (11.6%) of uncontrolled BP and higher level of hs-CRP ( >3mg/l) was in drug combination group. In conclusion, hypertensive patients treated with RAASI, NRAASI and drug combination and reached BP target showed significant reduction in hsCRP and NLR. Patients with uncontrolled BP treated with RAASIs revealed slightly lower hs-CRP than other groups. Careful selection of antihypertensive drugs may affect risks of CVD. This study recommends further prospective studies exploring the anti-inflammatory effect of antihypertensive drugs to ameliorate possible risks of cardiovascular disease.
ألفاظ الصعود والنزول عند سكان قرى بني سُليم الحجاز المعاصرة وعلاقتُها بالفصحى: (دراسة تحليلية)
Authors: السلمي نمر بن سعيد
Published: October 2024

تتناول هذه الدراسة الألفاظَ التي تدل على الصعود والنزول عند سكان قرى بني سُليْم الحجاز المعاصرة بالدراسة، وتحليل المعنى المعاصر والقديم، واستخداماتها، وشرح دلالات هذه الألفاظ، وإيراد الشواهد عليها من كلام العرب، ثم تعيين ما وافق منها الفصيح وما خالفه، وما طرأ عليها من تبديل وتغيير، مستفيدًا من المنهج الوصفي، التحليلي، وقد أحصت الدراسة اثنتين وعشرين لفظة، تستعمل منها اثنتي عشرة لفظة للصعود، في مقابل عشرة ألفاظ للنزول. توصي الدراسة بدراسة الألفاظ المستخدمة في الحياة المعاصرة، ومعرفة أصيلها من الدخيل عليها؛ لإثراء المعجم المعاصر بالكلمات الفصيحة المستخدمة في الحياة اليومية وإشاعتها.
The Influence of Medication Non-Adherence on the Occurrence of Drug-Resistant Tuberculosis
Authors: Handayani Reni Stefhanie , Hendarwan Harimat , Ratri Teja
Published: October 2024

Drug-resistant tuberculosis (DR-TB) presents a significant challenge to global TB control efforts, with medication non-adherence identified as a major contributing factor. This study aimed to investigate the influence of medication non-adherence on the occurrence of DR-TB in Serang City, Indonesia. Utilizing an observational analytic study with a case-control design, the research included 76 TB patients, comprising 38 DR-TB cases and 38 drug-sensitive TB controls. Data were collected from secondary sources and validated questionnaires and analyzed using univariate and bivariate methods, including Chi-square tests and Odds Ratios (OR). The findings revealed a significant relationship between medication non-adherence and DR-TB, with an OR of 11.56, indicating that non-adherent patients are 11.5 times more likely to develop DR-TB compared to adherent patients. However, demographic factors such as age, occupation, and education did not significantly influence the incidence of DR-TB. The study concludes that medication non-adherence is a critical risk factor for the development of DR-TB, underscoring the need for targeted interventions to improve treatment adherence, particularly through educational campaigns and community-based support. Health authorities are encouraged to implement intensive educational programs focused on the risks of non-adherence and ensure that TB treatment is accessible and supported by community health workers. Policymakers should allocate sufficient resources to these initiatives to effectively reduce the incidence of DR-TB.
Enhancing Maternal Comfort: The Impact of Endorphin Massage Therapy on Reducing Preoperative Pain and Anxiety in Primigravida Mothers Undergoing Cesarean Section
Authors: Azissah RS Danur , Rustandi Handi , Nuh Yalta Hasasnudin , Suyanto Jipri
Published: October 2024

Pain and anxiety are significant challenges for primigravida mothers undergoing cesarean sections, with potential adverse effects on both maternal and neonatal outcomes. Endorphin massage therapy has emerged as a non-pharmacological intervention to mitigate these challenges by promoting the release of endorphins, which act as natural analgesics and anxiolytics. This study aimed to evaluate the effectiveness of endorphin massage therapy in reducing preoperative pain and anxiety levels in primigravida mothers scheduled for cesarean sections in Lubuklinggau, Indonesia. A quasi-experimental design was employed, involving 21 primigravida mothers divided into intervention and control groups. The intervention group received endorphin massage therapy, administered twice daily for three consecutive days prior to the cesarean section. Pain and anxiety levels were measured using the Numeric Rating Scale (NRS) and the Hamilton Anxiety Rating Scale (HARS), respectively. Statistical analyses were conducted to compare the pre- and post-intervention scores. The study found a significant reduction in both pain (mean difference: -4.3; 95% CI: -1.92 to -8.71; p < 0.001) and anxiety levels (mean difference: -8.3; 95% CI: -2.1 to -11.2; p < 0.001) in the intervention group compared to the control group. The reduction in anxiety was more pronounced than in pain, indicating the potent anxiolytic effect of endorphin massage therapy. Endorphin massage therapy significantly reduces preoperative pain and anxiety in primigravida mothers undergoing cesarean sections, particularly in alleviating anxiety. This non-pharmacological intervention could be a valuable addition to standard peripartum care, offering a safe, cost-effective alternative to pharmacological treatments. Further research with larger sample sizes is recommended to confirm these findings and explore long-term outcomes.
Estimating The Prevalence of Non-Communicable Diseases and Adherence to Dietary Habits And Physical Activity Among Healthcare Professionals in The Middle East And North Africa Regions
Authors: Abdelhalim Nada , Eltewacy Nael Kamel , Owais Tarek A. , Salman Saif , Hamza Nouran , Islam Sheikh Mohammed Shariful
Published: October 2024

The rising number of fatalities linked to food, exercise, and non-communicable illnesses has sparked interest in studying their effects. In society, Healthcare Professionals (HCPs) symbolize health and wellbeing. However, the incidence of chronic illness and healthy habits among Middle East and North Africa (MENA) HCPs remains unclear. To determine the prevalence of chronic diseases and adherence to healthy dietary habits and physical activity among HCPs in the MENA region. Algeria, Egypt, El Yemen, Iraq, Jordan, Kuwait, Libya, Palestine, Saudi Arabia, Sudan, and Syria HCPs (physicians, dentists, nurses, pharmacists, and nutritionists) participated in multicenter cross-sectional research. April to June 2022 data on diet and exercise habits was collected using a pre-tested self-administered questionnaire. Demographics, risk factors, medical history, and nutrition and exercise were included in the questionnaire. HCP diet and exercise were examined using multivariable regression models. A study of 7130 HCPs (mean age 28.6 ± 7.8 years, 57.5% females) was conducted. Physicians held 56.8% of the sample population, followed by pharmacists, nurses, dentists, and nutritionists. Cardiovascular disease (CVD) affected 33.1% of individuals. Alcohol, pork, soda, sugar, and smoking raised the risk of non-communicable diseases. Nutritionists were the most active HCPs. About half of dietitians (45.3%) walked 150 minutes or more per week, while 14.7% and 25.9% did 150 minutes or more of moderate and 75 minutes or more of intense exercise, respectively. HCPs in MENA had high rates of CVD and risk factors such smoking, alcohol, pork, soda, sugar, and less exercise. MENA HCPs must be aware of the significant incidence of these risk factors to enhance health behavior.
Challenges in pre-service teachers’ reflective practice
Authors: Rakhimova Khumora
Published: October 2024

Reflective practice is evident in how pre-service teachers plan, design, implement, and evaluate their teaching approaches. Engaging in reflection can help pre-service teachers appreciate the value and passion for teaching, which is reflected in their professional practice. However, students often encounter challenges when writing reflections. This article explores the difficulties associated with reflective activities and suggests ways to enhance reflective practices.
THE CLASS VERBS IN NORMATIVE GRAMMAR (GENERAL CHARACTERISTICS WITH A DESCRIPTION OF CATEGORIES CONJUGATION, PERSON, NUMBER, TENSE AND IDENTIFICATION OF VERB INFLECTIONAL TYPES)
Authors:   Institute of Bulgarian Language “Prof. Lubomir Andreychin”,  Bulgarian Academy of Sciences, Stancheva Ruska
Published: October 2024

Based on the formal approach, the study characterizes the class of verbs in normative grammar. The categories of conjugation, person, number, tense are described and a number of new observations are made about their functioning in view of the current literary norms. Two new classifications are also proposed – in the structural characteristics of the tense category, as well as in the identification of verb inflectional types from the point of view of: combinatorics of the three temporal vowels, morphonological changes and normative features.
USES OF SAM, BADA, BIVAM AND BIDOH IN THE MODERN BULGARIAN LANGUAGE
Authors:   Sofia University St. Kliment Ohridski, Aleksova Krasimira
Published: October 2024

In the present study, the uses of sam, bada, bivam and bidoh as copulas or as auxiliary verbs in various evidentials and voices in the modern Bulgarian language are investigated. The competition between both sam and bada and between sam and bivam, byah and bidoh is explored. In addition, the opinion of modern Bulgarians about these three competing couples is studied through an anonymous non-representative survey. Examples are used from all electronic corpora of the Bulgarian language and from the Internet. The truth of three hypotheses is proven: the forms of sam are preferred over the uses of bada and bivam in the various evidential active forms; the forms of bada predominate in the passive evidential forms; the aorist forms bidoh, bide, bide, bidohme, bidohte, bidoha are very infrequent and today hardly used by modern generations, although they are known.
ABOUT SOME BASIC LEXICOGRAPHIC TERMS
Authors:   Institute of Bulgarian Language “Prof. Lubomir Andreychin”, Bulgarian Academy of Sciences, Georgieva Tsvetelina
Published: October 2024

The study is the first attempt in Bulgarian linguistics to purposefully present and define basic lexicographic terms such as dictionary entry, headword, etc. with a view to an explanatory dictionary. It answers the question of how many headwords there are in the headwords area in the unconventional cases where the „input“ of the entry are several words of the same type that are interpreted together. One of the stated recommendations is to follow the theoretical postulate: one headword (simple or combined) unlocks one dictionary entry.
TRUTH UNTIL PROVEN OTHERWISE: THE RENARRATIVE AND ITS POSSIBLE (IN)USES IN JOURNALISTIC HEADLINES TODAY
Authors:   GATE Institute, Sofia University St. Kliment Ohridski, Margova Ruslana
Published: October 2024

The research starts from the hypothesis that renarrative in Bulgarian can be used in journalistic texts to report something that is not necessarily verified and reliable, according to the requirements of the journalistic profession. News headlines analyzed through the prism of the use of renarrative show a tendency to move away from this grammatical form in an attempt to prove that only the truth is being spoken.
INSCRIPTIONS ON BELLS FROM THE CHURCHES IN THE SMOLYAN DISTRICT – EPIGRAPHIC MONUMENTS FROM THE END OF THE 19TH AND THE FIRST HALF OF THE 20TH CENTURY
Authors:   Institute of Bulgarian Language “Prof. Lubomir Andreychin”, Bulgarian Academy of Sciences, Mitrinov Georgi
Published: October 2024

The study is dedicated to the inscriptions on bells from the churches in the Smolyan parish of the Plovdiv diocese. The inscriptions on over 50 church bells have been studied. A thematic classification was made for them, as well as a diachronic classification. Their graphic features are examined. Technical data of the bells and historical information about them are presented. Information is included on the decoration of the bells, as well as on the master bellwrights.
Küresel Dijital Rekabet Edebilirlik Endeksi Analizi: Entropi Tabanlı Topsıs Yaklaşımı
Authors: Şişman Senay , Keskin Tuba , Nebati Emine Elif
Published: October 2024

Günümüzün hızla değişen ve dijitalleşen dünyasında, ülkelerin rekabet gücünü artırabilmesi ve sürdürülebilir ekonomik büyümeyi sağlayabilmesi için dijital teknolojilere uyum sağlaması kritik bir öneme sahiptir. Bu bağlamda, dijital ekonominin dinamiklerini anlamak ve dijital dönüşüm süreçlerini yönetebilmek, küresel arenada başarılı olmanın anahtarı haline gelmiştir. Uluslararası Yönetim Geliştirme Enstitüsü (IMD) tarafından yayımlanan Küresel Dijital Rekabet Edebilirlik Endeksi, ülkelerin dijital rekabet düzeylerini ölçmek ve küresel ekonomideki yerlerini belirlemek için temel bir araç olarak ön plana çıkmaktadır. Bu çalışmanın amacı; Entropi ve TOPSIS çok kriterli karar verme yöntemlerinin entegre bir şekilde kullanılarak IMD Küresel Dijital Rekabet Edebilirlik 2023 raporunda yer alan puanlar doğrultusunda, 64 ülkeyi yeniden sıralamak ve rapordaki sıralamayla karşılaştırmaktır. Elde edilen veriler değerlendirildiğinde, dijital rekabet edebilirlik endeksine göre önemli faktör “Teknoloji” olarak ortaya çıkmıştır. İlk iki sırada ABD ve Hollanda yer almaktadır. Elde edilen TOPSIS sıralaması ve raporda yer alan sıralama ile karşılaştırıldığında, “Teknoloji” puanı yüksek olan ülkelerin birçoğunun TOPSIS sıralamasında yükseldiği gözlemlenmiştir. Çalışmanın sonuç kısmında ise ülkelerin dijital rekabet edebilirlik gücünü artırmaya yönelik birtakım stratejik öneriler sunulmuştur.
Molecular Identification and Antifungal Activity of Candida chrysomelidarum and Rhodotorula toruloides Isolated from Indonesian Indigenous Fruit Flacourtia inermis Roxb. (Lobi-lobi) against Pathogenic Mold Aspergillus flavus
Authors: Sukmawati Dalia , Nurmayanti Faradila , Supiyani Atin , Kurniati Tri Handayani , Adisyahputra Adisyahputra , Tawfeeq Al-Ani Laith Khalil , Widowati Retno , Nida Al Husna Shabrina , Hidayat Iman , Bimo Setiarto Raden Haryo , Sulistiani Sulistiani , Abdul Rahman Roshanida
Published: October 2024

Aspergillus flavus is one of the main contaminating mold species in most feed products, significantly impacting human and animal health. This study aims to isolate the epiphytic yeasts from the fruit Flacourtia inermis Roxb and test their potential ability to act as biocontrol agents for A. flavus. The antagonistic test was performed using a dual culture method, and the potential yeast isolates were then identified using a combination of morphology characterization and molecular sequence analysis. From 42 yeast isolated from F. inermis fruit, 2 yeast isolates (LCA 75 and LCA 102) demonstrated the highest inhibition growth against A. flavus (32.32 and 32.30 %, respectively). The isolates LCA 75 and LCA 102 were identified as Candida chrysomelidarum and Rhodotorula toruloides, respectively. Rhodotorula toruloides, identified as one of the yeast isolates (LCA 102), is an unconventional red yeast demonstrating notable antagonistic effects against A. flavus, inhibiting its growth by 32.30 %. This yeast, also known as Rhodosporidium toruloides, R. rubescens, R. glutinis, or R. gracilis, belongs to the subphylum Pucciniomycotina within the division Basidiomycota. The significant inhibition of mycelium growth and sporulation observed in our study highlights the potential of R. toruloides, along with C. chrysomelidarum (LCA 75), as effective biocontrol agents to reduce mycotoxin contamination in chicken feed by A. flavus. This study represents a significant advancement in the management of A. flavus contamination in animal feed. The findings not only underscore the viability of yeast-based biocontrol strategies but also contribute to a safer, more sustainable approach to preventing mycotoxin proliferation in feedstocks.
HIGHLIGHTS

Founding Out of 42 yeast isolates, two (LCA 75 and LCA 102) demonstrated the highest inhibition growth against A. flavus, with inhibition rates of 32.32 and 32.30 %, respectively.
Identified Yeasts: LCA 75 as Candida chrysomelidarum LCA 102 as Rhodotorula toruloides (alternatively referred to as Rhodosporidium toruloides, R. rubescens, R. glutinis, or R. gracilis).
Characteristics of Rhodotorula toruloides Unconventional red yeast belonging to the subphylum Pucciniomycotina within Basidiomycota. Commonly associated with various plant species and found on plant surfaces, including leaves, stems, and fruits.
Identified yeast isolates exhibited inhibition activities leading to reduced mycelium growth and sporulation of A. flavus.
These yeast isolates have potential as biocontrol agents to prevent mycotoxin contamination in chicken feed caused by A. flavus.

GRAPHICAL ABSTRACT
An Analysis of Dental Fricative Sound’s Production
Authors: Hasan Ibrahim , Sakti Genta , Reflinda Reflinda , Syahrul Syahrul
Published: October 2024

This research was motivated by the problems of students of the English education study program at UIN Sjech M. Djamil Djambek Bukittinggi. Some students pronounce the dental fricative sound in various ways. First, some students pronounce the sound /?/ correctly, however, there are also some students pronounce the sound /?/ by replacing it with the sound /t/. Second, some students pronounce the sound /ð/ correctly, however, there are also some students pronounce the sound /ð/ by replacing it with the sound /d/. The researcher's question in this study was how students pronounce the dental fricatives sound at the initial, medial and final position of a word based on the PRAAT application. The purpose of this study was to analyze the way students pronounce the dental fricative sound at the initial, middle and final of a word based on the PRAAT application. This study uses a qualitative research method with seventh semester students as the research population. The research sample amounted to 13. Data was collected through audio recordings. Students are asked to pronounce 12 words that contain the sound of dental fricative sound. The sound is uploaded to the PRAAT software. The results showed that some of the students pronounce the dental fricative sound correctly, showed by a spectogram display like a scribble pattern in the focus phoneme. others pronounce the dental fricative sound incorrectly, showed by an empty area on spectrogram in the focus  phoneme. It showed that they replaced the phoneme with another phoneme such as /t/ or /d/. Researchers can conclude as follows. First, some students pronounce the dental fricative sound correctly. Second, most of the students pronounce the dental fricative sound incorrectly.
The Impact of Management Information Systems on Organizational Performance
Authors: MIoD, FCGBA Lord Emmanuel Yamoah, PhD, , MIoD, FCGBA Edward Domina Attafuah, PhD, , Nketia, PhD Dr. Mark Ofori
Published: October 2024

Business managers today, are much more concerned about the effect of competition than they were even a few years ago (McKenzie, 2021). Maintaining and improving performance in an increasingly complex and competitive global operating environment, where change pressures appear to be the only constant, is a major challenge for any organization (Lonial and Carter, 2015). The importance of information is critical for achieving short, intermediate, and long-term objectives (Riahi et al., 2015). However, it should be noted that not just any information provides a competitive advantage, but information that is timely, relevant, and accurate, which is where management information systems (MIS) come into play (Sousa and Oz, 2015). Deregulation has also increased competitive pressure for organizations to survive, grow and prosper. In such a competitive environment, managers employ a lot of the resources at their disposal as efficiently as possible so as to accomplish the objectives and goals of the enterprise (Ikechukwu et al., 2019).
A Decolonial Reimagining of Workplace Spirituality: Embracing Sufi Wisdom in the Quest for Meaningful Enchantment
Authors: Ul-Haq Shoaib
Published: October 2024

This paper critically examines the human quest for meaning and enchantment in the context of modernity's disenchanting tendencies and the subsequent emergence of co-opted forms of re-enchantment. It argues that while the workplace spirituality movement attempts to address the crisis
of meaning in organizational life, it often reproduces neoliberal capitalist rationality embedded in coloniality. Drawing on decolonial theory, the paper proposes engaging with Islamic spirituality, Sufism, as a means to generate a radical imaginary capable of providing deeper meanings and
expanding human potentialities. The concept of ishq-i haqqiqi (intense love of the Divine) is presented as a cornerstone for reimagining enlightenment in more holistic and spiritually grounded terms. This approach offers promise not only for addressing existential and moral crises but also
for fostering more humane and sustainable forms of social and economic organization. The paper contributes to ongoing discussions about the role of spirituality in management and organizational studies by offering a decolonial perspective that challenges dominant Western paradigms and opens
up new possibilities for understanding human flourishing in organizational contexts.
Syedra Antik Kenti Büyük Hamam Yapısı’nın Palestra Mozaikleri
Authors: Ergürer Hatice
Published: October 2024

Dağlık Kilikia Bölgesi (Cilicia Tracheia) kentleri içerisinde bulunan Syedra Antik Kenti Antalya İli’nin Alanya İlçesi’nde, ilçe merkezine yaklaşık 20 km uzaklıktaki Seki Köyü’nde yer almaktadır. Denizden 400 m yükseklikteki kent, ismini “Sedre Çayı” ndan almaktadır. Yüksekçe bir tepe ve onun kıyıya uzanan eteklerine konumlandırılmış kentte, 2019 yılında ilk sistemli kazılar gerçekleştirilmiş ve çalışmalar Büyük Hamam’ın frigidaryum bölümüyle eş zamanlı olarak palestrada da yürütülmüştür. Bu çalışmalar sırasında palestranın Roma Dönemi taban mozaikleri ve Geç Antik Çağ havuzu açığa çıkartılmıştır. Söz konusu bu çalışmada palestraya ait taban mozaikleri ve geç dönem havuzu incelenmiş, yapılan analojik, stilistik ve üslupsal değerlendirmeler sonucu Büyük Hamam’ın palestrasına ait Roma Dönemi mozaik döşemin MS 3. yüzyıl başı ya da ortalarına, Geç Antik Dönem havuzunun ise MS 6. yüzyıl başı veya son çeyreğine tarihlenebileceği anlaşılmıştır.
TÜRK ASKERÎ MÜZİĞİNE FARKLI BİR BAKIŞ: ASKERÎ CAZ ORKESTRALARI
Authors: Demirtaş Erkan , Karaaslan Serkan
Published: October 2024

Askerî müzik denildiğinde akla ilk marşlar gelmektedir. Dünyanın pek çok ordusunda olduğu gibi Türk askerî müzisyenleri, marşlarla beraber farklı müzik türlerini de icra etmektedir. 20. yüzyıl başlarında adını etkin bir şekilde duyurarak gelişen caz müziği de bunlardan birisidir. Anavatanı Amerika’dan başlayarak bütün dünyaya yayılan caz müziği ile ilk tanışmalar Osmanlı zamanına denk gelmektedir. 1826 yılında kurulan Muzika-i Hümayun ile Türk askerî müziği dönüşüm geçirerek batı tarzı bando modeline geçmiştir. Kuruluşundan beri yaklaşık 200 yıldır faaliyet gösteren Türk askerî bandoları, üflemeli enstrümanların ön planda olduğu caz müziği ile de ilgilenmişlerdir. Bu çalışmada Türk Silahlı Kuvvetleri bünyesinde bulunan askerî müzik kurumlarında faaliyet gösteren caz orkestralarının tarihsel ve güncel durumu ortaya konmaya çalışılmıştır. Araştırma görüşme ve doküman analizi tekniklerinin kullanıldığı nitel bir çalışmadır. Çalışma grubu Türk Silahlı Kuvvetleri bünyesindeki caz orkestralarında görev yapmış şef ve enstrüman sanatçılarından oluşturulmuştur. Görüşmeler metin haline getirildikten sonra araştırma amacına yönelik olarak analiz edilmiştir. Görüşme analizleri ve dokümanlardan elde edilen bulgular Kara, Deniz ve Hava Kuvvetleri özelinde robotlaştırılarak sunulmuştur.
The Environmental and Health Implications of Microplastics on Human and Aquatic Life
Authors: OFOEGBU Obinna , ONUWA Peter O. , Kelle Henrietta Ijeoma , ONOGWU Sarah U. , AJAKAYE Oluwadolapo J. , LULLAH-DEH Japheth A. , EGWUMAH Joy , UNONGUL Teryima Philip
Published: October 2024

The pervasive presence of microplastics in the environment has emerged as a significant concern due to their potential health implications for both human and aquatic life. Microplastics are plastic particles smaller than 5 millimeters, originated from various sources, including the degradation of larger plastic debris, industrial processes and consumer products. In aquatic ecosystems, microplastics are ingested by a wide range of organisms, from plankton to fish, leading to physical and chemical impacts. These particles can cause internal injuries, blockages, and alterations in feeding behavior, ultimately affecting growth, reproduction, and survival rates of marine species. The bioaccumulation and biomagnification of microplastics and associated pollutants further aggravates these effects and eventually disrupting entire food webs. However, human exposure to microplastics occurs through multiple pathways including consumption of contaminated seafood, drinking water and inhalation of airborne particles. Studies have shown that microplastics can translocate across the gastrointestinal tract and accumulate in various tissues, raising concerns about their potential toxicity. The health implications for humans include inflammatory responses, cytotoxicity and potential endocrine disruption. Although extensive long-term studies are still needed to fully understand these effects. Microplastics can also act as vectors for harmful chemicals and pathogens, further complicating their impact on health. Additionally, addressing the issue of microplastic pollution requires a multi-faceted approach, encompassing improved waste management practices, reduction in plastic production and use, and enhanced public awareness. Research into alternative materials and innovative technologies for plastic degradation is also essential. By mitigating the sources and impacts of microplastics, we can safeguard the health of both aquatic ecosystems and human populations.
HUBUNGAN TINGKAT PENGETAHUAN DAN DUKUNGAN TENAGA KESEHATAN LINGKUNGAN TERHADAP PERILAKU PENGELOLAAN SAMPAH DI BANK SAMPAH RAMLI GRAHA INDAH
Authors: ROVANDA IRVAN GUSTIAWAN , RUSDI RUSDI , YULIAWATI RATNA
Published: October 2024

Waste is now one of the problems that requires special attention, because waste has now become a national problem. Waste will increase in line with the increasing population in an area. Community consumption patterns also contribute to the increasing amount of waste that is increasingly diverse in type. This study was conducted with the aim of determining whether or not there is a relationship between the level of knowledge and support of environmental health workers in waste management at the Ramli Graha Indah waste bank. A quantitative approach with a cross-sectional research design was implemented in this study. Bivariate and univariate data analysis will be used in this process. The results of the study showed no relationship between the level of knowledge and waste management behavior with a sign value of 0.666 (p>0.05). There was no relationship between the support of environmental health workers for waste management behavior with a sign value of 1.000 (p>0.05). There was no relationship between the level of knowledge and support of environmental health workers for waste management behavior at the Ramli Graha Indah Air Putih waste bank. It is hoped that environmental health workers can collaborate with the management of the Ramli Graha Indah Air Putih waste bank to mobilize the community so that waste can be managed properly.
ABSTRAKSampah kini menjadi salah satu permasalahan yang memerlukan perhatian khusus, sebab sampah saat ini sudah menjadi persoalan nasional. Sampah akan meningkat sejalan dengan meningkatnya jumlah penduduk di suatu wilayah. Pola konsumsi masyarakat ikut memberi kontribusi dalam meningkatnya jumlah timbulan sampah yang semakin beragam jenisnya. Penelitian ini dijalankan dengan tujuan agar ada tidaknya hubungan yang terjadi pada tingkat pengetahuan dan dukungan tenaga kesehatan lingkungan pada pengelolaan sampah bank sampah Ramli Graha indah bisa diketahui. Pendekatan kuantitatif dengan bentuk desain penelitian cross-sectional diimplementasikan dalam studi ini. Analisis data bivariat dan univariat akan dipakai dalam proses ini. Hasil penelitian tidak ada hubungan antara tingkat pengetahuan terhadap perilaku pengelolaan sampah dengan nilai sign 0,666 (p>0,05). Tidak ada hubungan antara dukungan tenaga Kesehatan lingkungan terhadap perilaku pengelolaan sampah dengan nilai sign 1,000 (p>0,05). Tidak ada hubungan antara tingkat pengetahuan dan dukungan tenaga Kesehatan lingkungan terhadap perilaku pengelolaan sampah di bank sampah Ramli Graha Indah Air Putih. Diharapkan tenaga kesehatan lingkungan bisa berkolaborasi dengan pengurus bank sampah ramli graha indah air putih untuk menggerakkan masyarakat agar sampah bisa dikelola dengan baik.
MANIFESTAÇÕES CARDIOVASCULARES EM PACIENTES COM HIPOGONADISMO MASCULINO: COMPLICAÇÕES CLÍNICAS E AVALIAÇÃO CIRÚRGICA
Authors: Freitas Letícia Assis Rodrigues , Santos Pedro Henrique Souza , Oliveira Leonardo de Almeida , Gonçalves Laura Coutinho
Published: October 2024

Introdução: O hipogonadismo masculino, caracterizado pela produção inadequada de hormônios sexuais, tem se revelado uma condição com implicações significativas para a saúde cardiovascular. Estudos demonstraram que baixos níveis de testosterona estão associados a um aumento do risco de doenças cardiovasculares, como hipertensão, infarto do miocárdio e insuficiência cardíaca. A relação entre hipogonadismo e complicações cardiovasculares pode ser explicada por fatores como resistência à insulina, obesidade e alterações na função endotelial. Portanto, compreender essas manifestações é crucial para o manejo clínico adequado e a avaliação de intervenções cirúrgicas em pacientes afetados. Objetivo: Avaliar a literatura existente sobre as manifestações cardiovasculares em pacientes com hipogonadismo masculino, enfocando suas complicações clínicas e a abordagem cirúrgica. Metodologia: A metodologia foi baseada no checklist PRISMA, utilizando as bases de dados PubMed, SciELO e Web of Science. Os cinco descritores utilizados foram: "hipogonadismo masculino", "saúde cardiovascular", "testosterona", "doenças cardiovasculares" e "avaliação cirúrgica". A pesquisa foi restrita a artigos publicados nos últimos dez anos. Os critérios de inclusão consistiram em estudos clínicos com homens diagnosticados com hipogonadismo, artigos que abordaram complicações cardiovasculares e pesquisas que discutiram intervenções cirúrgicas. Os critérios de exclusão abrangeram revisões não sistemáticas, estudos que não focaram em homens e artigos com dados não disponíveis em inglês, português ou espanhol. Resultados: Os resultados indicaram que o hipogonadismo masculino estava associado a uma prevalência elevada de eventos cardiovasculares adversos. Observou-se que a terapia de reposição de testosterona poderia melhorar parâmetros cardiovasculares em alguns pacientes, mas também trouxe à tona preocupações sobre potenciais riscos. As intervenções cirúrgicas, quando necessárias, exigiam uma avaliação cuidadosa do risco cardiovascular. Conclusão: O hipogonadismo masculino apresenta um impacto significativo nas manifestações cardiovasculares, o que requer uma abordagem clínica abrangente. A revisão da literatura destacou a importância de monitorar essas complicações e considerar a terapia de reposição de testosterona com cautela, enfatizando a necessidade de mais pesquisas para elucidar as melhores práticas no manejo cirúrgico desses pacientes.
TRANSTORNO AFETIVO BIPOLAR: UMA REVISÃO DE LITERATURA
Authors: Nunes Fernanda Lino , Rocha Daniela Almeida , Chaves Vitória Dias Riguete , Aguiar Gustavo Daniel dos Santos Sousa
Published: October 2024

Introdução: O transtorno afetivo bipolar é uma condição psiquiátrica caracterizada por alterações extremas de humor, variando entre episódios de mania e depressão. Esta desordem, que afeta uma parcela significativa da população, apresenta desafios tanto para o diagnóstico quanto para o tratamento. Os episódios maníacos são marcados por uma elevação do humor, aumento da energia e comportamento impulsivo, enquanto os episódios depressivos envolvem sentimentos de tristeza profunda, apatia e perda de interesse. As causas do transtorno são multifatoriais, envolvendo interações complexas entre fatores genéticos, neuroquímicos e ambientais. A compreensão desse transtorno é essencial para o desenvolvimento de intervenções mais eficazes e para a melhoria da qualidade de vida dos afetados. Objetivo: Analisar as evidências existentes sobre o transtorno afetivo bipolar, abordando aspectos relacionados ao diagnóstico, tratamento e impacto na vida dos pacientes. Metodologia: A metodologia seguiu o checklist PRISMA, utilizando as bases de dados PubMed, SciELO e Web of Science. Foram empregados cinco descritores: "transtorno afetivo bipolar", "diagnóstico", "tratamento", "epidemologia" e "qualidade de vida". Os critérios de inclusão consistiram em artigos revisados por pares, publicados nos últimos 10 anos, que abordaram de maneira abrangente os aspectos do transtorno. Os critérios de exclusão foram artigos com foco em transtornos não relacionados, estudos com amostras menores que 30 participantes e publicações não acessíveis em texto completo. Resultados: Os resultados indicaram que o tratamento do transtorno afetivo bipolar deve ser multidisciplinar, envolvendo psicoterapia e farmacoterapia, com foco em estabilizadores de humor e antipsicóticos. O impacto na qualidade de vida dos pacientes foi evidenciado, mostrando que o suporte social e terapias complementares são essenciais para o manejo da condição. Além disso, as evidências destacaram a importância do diagnóstico precoce e do seguimento contínuo. Conclusão: A revisão sistemática evidenciou a complexidade do transtorno afetivo bipolar, ressaltando a necessidade de um manejo holístico que considere não apenas os sintomas, mas também as dimensões sociais e psicológicas que afetam os pacientes. A promoção de estratégias integradas pode melhorar significativamente os resultados clínicos e a qualidade de vida dos indivíduos afetados.
NEOPLASIA TROFOBLÁSTICA GESTACIONAL: DIAGNÓSTICO, TRATAMENTO E PROGNÓSTICO
Authors: Ferreira Luísa Moita , Silva Álvaro Antônio Martins , Silva Neto Aníbal Lataliza , Ferreira Julia Caramatti
Published: October 2024

A neoplasia trofoblástica gestacional (NTG) compreende um grupo raro de tumores que surgem do trofoblasto, tecido responsável pela formação da placenta. Esses tumores incluem a mola hidatiforme, mola invasora, coriocarcinoma e o tumor trofoblástico do leito placentário, sendo a mola hidatiforme a forma mais comum. A NTG pode se manifestar após qualquer tipo de gestação, incluindo abortos e gestações ectópicas, e afeta 1 a cada 1000 a 2000 gestações no mundo. A NTG é caracterizada pelo crescimento anômalo do tecido trofoblástico, com potencial invasivo local e capacidade de metástase. O diagnóstico é baseado em níveis elevados de gonadotrofina coriônica humana (hCG), ultrassonografia e, em casos mais avançados, tomografia computadorizada ou ressonância magnética. O tratamento inclui desde a curetagem uterina até quimioterapia, dependendo do tipo e da extensão da doença. Em casos de mola hidatiforme, a maioria das pacientes responde bem à curetagem e monitoramento do hCG. Contudo, em casos malignos, a quimioterapia é altamente eficaz, resultando em taxas de cura superiores a 90%. A monitorização regular dos níveis de hCG após o tratamento é crucial para detecção precoce de recidivas.