bluuebunny/crossref_metadata_2025 huggingface dataset:
History and Experience of Central Sulawesi Communities Facing the Influenza Pandemic 1918—1920
Authors: Setiawan Adi , Nurhalisa Nurhalisa , Pratiwi Nanda , Haliadi Haliadi
Published: December 2022

This study aims not only to explain the handling efforts, but also to analyze the experiences and collective memories of the people of Central Sulawesi when they faced influenza pandemic in 1918—1920. A century ago, before the Covid-19 pandemic broke out in 2020, an influenza pandemic had plagued the people of Central Sulawesi. Unfortunately, there was very little literature describing these cases. Hence, historical method is used together with certain sources, such as books, journal articles, newspapers, archives, and interviews related with the issue. The results then show that the influenza pandemic in Central Sulawesi began in late 1918 and lasted until the early 1920s. The colonial government at that time tended to be late in dealing with this pandemic. As a result, treatment efforts at the local level were mostly driven by missionaries and colonial officers who had been equipped with the knowledge of modern medicine for tropical diseases. In addition, certain tactics were carried out by several local communities including migration, self-quarantine, and prevention efforts by implementing a hygiene lifestyle and providing food barns to prevent famine during a pandemic. In conclusion, efforts to deal with the influenza pandemic in Central Sulawesi were very limited due to the lack of health facilities and the number of medical personnel, so it was not sufficient to overcome the disease and its spread. However, people's experiences with influenza at that time were stored quite well in their collective memory. Therefore, some of these experiences related to local knowledge can be used as lessons to deal with the current Covid-19 pandemic.
The Function and Meaning of Megalithic Cultural Heritage in Some Sites in Bantaeng Regency, South Sulawesi
Authors: Rosmawati Rosmawati , Duli Akin , Nur Muhammad , Yusriana Yusriana , Saraka Erwin Mansyur Ugu , Muda Khadijah Thahir , Stephen Chia  , Yunus Sauman Sabin  , Zuliskandar Ramli  , Francis David Bulbeck  , Adam Brumm
Published: December 2022

The Bantaeng megalithic site houses megalithic cultural relics, such as terraces (teras berundak), dakon, lumpang batu, menhir, dolmen, stone altars, circular stone (batu temu gelang), tombs, and fences, including fragments of pottery and foreign ceramics on the surface of the site. In addition, residents on the site also preserves and performs traditional megalithic rituals. This study aims to find out the functions and meanings of these megalithic cultural relics using surveys, inventory studies, and interviews to the local community. The results indicate that the megalithic culture functions both as a sacred medium of ritual, and a secular instrument of daily life. Furthermore, some of the elements of megalithic culture have symbolic meaning which are related to social status, cosmic symbols, agriculture, astrology, and religious symbols.
Literacy Learning Model Based on Surabaya’s Local Identities in Community-Based Libraries of Surabaya
Authors: Wulan Nur , Karnanta Kukuh Yudha , Sukmawati Ni Luh Ayu , Karyanto Puji
Published: December 2022

This study investigates the ways bottom-up learning, specifically discovery and project-based learning, in strengthening local wisdom and identities among the youths in Surabaya. The local identities of Surabaya are generally associated with being egalitarian, urban, and multicultural. Despite the strong association of Surabaya with the bravery of Surabaya youths in the 1945 war against the Allied troops (semangat arek Suroboyo), young people of Surabaya nowadays do not internalize the spirit strongly. Our preliminary observation suggests the fact, and this can be seen from their writings before joining the writing class that we conducted. In coordination with the Public Library of Surabaya (Municipal Library and Archive of Surabaya) and community-based libraries in Surabaya, this experimental research was conducted to gain insights on the extent to which discovery and project-based learning can stimulate junior high school students to be more aware of their locally rooted identities. The study shows that the application of the student-centered learning methods can contribute significantly to the internalization and representation of Surabaya identities reflected in the students’ writings.
Factors Associated with Exclusive Breastfeeding Practice by Mothers who Work as Health Workers
Authors: Iswara Salma 'Afindi , Utomo Martono Tri , Ningtyas Woro Setia
Published: December 2022

Introduction: Health workers play a notable role as "the significant others" in increasing maternal awareness and participation in fulfilling exclusive breastfeeding practices. In this case, female health workers tend to be the role models for other mothers in the community, including their child-feeding behavior. Based on the existing knowledge and work experience, female health workers should be able to breastfeed their babies exclusively. Yet several previous studies have shown the opposite result. This study aimed to analyze the factors associated with exclusive breastfeeding practice by mothers who work as health workers in Tulungagung Regency Public Health Centers.
Methods: This study used a cross-sectional method. The sample in this study was 56 breastfeeding mothers who work as health workers in Tulungagung Regency Public Health Centers, selected by purposive sampling technique. Data were collected using a questionnaire and analyzed using the Chi-Square correlation test with a confidence limit of α=0.05.
Results: Knowledge (p=0.091), attitude (p=0.094), and working shifts (p=0.185) did not correlate with exclusive breastfeeding practice. Husband's support (p=0.000) and family support (p=0.024) correlated significantly with exclusive breastfeeding practice.
Conculusion: The breastfeeding mothers working as health workers who get a lot of support from their husbands and families tend to be confident to continue exclusively breastfeeding their babies despite returning to the workplace. The following researchers are expected to research other factors not examined in this study on a larger population and a more diverse health institution to determine how influential those factors are toward the exclusive breastfeeding practice.
The Relationship Of Family Centered Care Implementation With Mother's Stress And Satisfaction With Services In The Edelweiss Room (Perinatology) At Regional Hospital Of Balung Jember District
Authors: Rahmawati Ira , Mardiyah Istna Abidah , Wahidah Ami ‘Alaili
Published: December 2022

Introduction: Neonatal intensive care causes high maternal stress, and low interaction between mother and baby are suspected to be a stressor. The role of the mother needed to participate in neonatal care. However, mothers want to monitor the condition of neonates during treatment. This purpose of study to analyze the correlation between family center care, stress and maternal satisfaction in the Edelweiss (Perinatology) at RSD Balung Jember.
Methods: A cross-sectional study was conducted among 124 post partum mothers whose babies were treated in the perinatology room with consecutive random sampling. Family center care, stress, and maternal satisfaction questionnaires were used. A Chi-square test was used to analyze to answer the research
Results: The results among respondents had high levels of family centered care implementation (63.7%), low maternal stress (51.6%), and high levels of maternal satisfaction (58.1%). There is a correlation between between family centered care implementation with maternal stress (X2 = 8.14; p-value = 0.004), and stress with maternal satisfaction (X2 = 19.3; p-value = 0.00). Mothers with high levels of family centered care implementation will prevent 0.2 times experiencing stress (OR = 0.16; 95% CI = 0.07-0.38), and if maternal satisfaction is high then 3 times will tend to have low stress (OR = 2.89; 95% CI = 1.38-6.06). However, there isn’t correlation between family centered care implementation and satisfaction mother (X2 = 0.83; p-value = 0.36). Perhaps, maternal characteristics to be a factor.
Conculusion: Family center care services can meet the needs of parents and improve the quality of nursing care in the perinatology room for babies, parents and families so as to increase satisfaction with the services provided.
Readiness analysis of archives instruments 3 in 1 model in the effectiveness of dynamic archives management
Authors: Hikmawan Try , Santoso Budi , Imaniyati Nani
Published: December 2022

Background of the study: The focus of this problem is to be able to find out the effectiveness and impact received from dynamic archive management in the agency, namely in managing general dynamic archive documents;
Purpose: The purpose of this study is to identify the effectiveness of archive management by archive management officers;
Method: The method used in this study uses descriptive qualitative methods and uses observation, interviews and documentation techniques;
Findings: The readiness of the dynamic archive archive instrument 3 in 1 model can be used in dynamic archive management with the implementation of Creation, Use, Maintenance, and Depreciation;
Conclusion: The use of 3 in 1 archival instruments has a positive impact and increases effectiveness in archive management.
Berita Pustaka as historical source of Bandung Institute of Technology Library in 1970’s
Authors: Supratman Frial Ramadhan
Published: December 2022

Background of the Study: History of Indonesian library is less explored field in library studies. Debates on history of Indonesian library seems to be unexplored due to pressure on librarian to adapt with technological changes. It causes development of history of Indonesian library seems stagnant among scholars of library science and librarians. Meanwhile, in the field of history itself, library history is less attractive for historians. The development of historiography since 1980’s is more concerned with social movement history, though library played significant role in the field of education and research in Indonesia. Almost all research centers and universities certainly need library for obtaining references.
Purpose: This article observes one of National Library of Indonesia’s rare collection named Berita Pustaka. The collection is a tabloid published by Center Library of Bandung Institute of Technology (ITB) in 1970’s. Today the collection is still deposited in Rare Newspaper Division, National Library of Indonesia with call number QQ-131.
Method: In this article author uses qualitative method along with deep  analysis of Berita Pustaka. Therefore, author also uses historical approach as a methodology in this article.
Finding: In addition, the collection also contains information regarding library service for faculty members and students in 1970’s.
Conclusion: Author argues that Berita Pustaka is an information source for researching history of Indonesian library, particularly higher education library.
PENERAPAN RPP KOLABORASI MATA PELAJARAN SEBAGAI PEMBELAJARAN BERBASIS PROYEK DI SMA PLUS TEKNOLOGI SUKABUMI
Authors: Farhin Nurul , M Nurul Ikhsan Saleh
Published: December 2022

Proses pembelajaran yang dilakukan tidak terlepas dari pengaruh perkembangan teknologi dan komunikasi. Semakin berkembangannya IPTEK maka dunia pendidikan juga perlu melakukan upgrade untuk menciptakan inovasi baru dalam proses pembelajaran. RPP adalah salah satu hal penting yang menunjang proses pembelajaran. Salah satu inovasi pembelajaran yang dapat dilakukan adalah RPP Kolaborasi. RPP Kolaborasi merupakan model inovasi pembelajaran berbasis proyek dimana dalam pembuatannya disesuaikan dengan profil murid. Dalam RPP Kolaborasi juga berfokus pada model pembelajaran student centered learning dengan menggunakan prinsip Merdeka Belajar dan 5M. Tujuan dari penelitian ini adalah untuk mengetahui hasil dari penerapan pembelajaran berbasis proyek yang dilakukan melalui RPP Kolaborasi di SMA Plus Teknologi (Kelas X). Metode yang digunakan adalah metode penelitian kualitatif berjenis studi kasus dengan menganalisis topik yang diteliti. Pengumpulan data lewat dokumentasi dan wawancara mendalam. Penelitian ini menemukan bahwa penerapan RPP kolaborasi Mapel menjadi inovasi baru dalam pembelajaran, RPP kolaborasi efektif dan efisien dimana dalam proses pembelajaran menjadi lebih praktis, dan penerapan RPP kolaborasi Mapel memuaskan dalam persepsi guru dan siswa.
MITIGASI PEMBELAJARAN DARING MELALUI SOSIALISASI PEMANFAATAN AKUN BELAJAR.ID
Authors: Tri Sanjaya Langgeng , Miratun Nur Arifah
Published: December 2022

Kondisi negara Indonesia juga masih belum bisa menjamin masyarakat akan terbebas dari virus covid-19, bahkan selalu memiliki prediksi terkait dengan peningkatan-peningkatan gelombang kasus pandemic covid-19. Hal tersebut akan berpengaruh terhadap sektor Pendidikan di Indonesia. Sistem daring yang di jalankan selama pandemic covid-19 lalu lebih banyak menggunakan Platform WhatsApp, yang dinilai masih banyak kekurangan terutama terkait fitur-fitur yang kurang mendukung kegiatan belajar mengajar, artinya masih memiliki nilai ketidakefektifan proses pembelajaran. Dalam rangka menjamin kelancaran proses pembelajaran, memudahkan pendidik dan peserta didik dalam mengakses layanan pembelajaran Kemendikbud melalui Pusat Data dan Teknologi Informasi (Pusdatin) meluncurkan akun Pembelajaran dengan domain belajar.id akun elektronik tersebut dapat digunakan peserda didik, pendidik, dan tenaga kependidikan untuk mengakses layanan pembelajaran berbasis elektronik, tidak terkecuali dalam rangka pemberian materi dan pengumpulan tugas peserta didik. Pengabdian ini bertujuan untuk mengetahui proses aktivasi akun belajar.id pada pendidik dan peserta didik dan untuk mengetahui proses implementasi akun belajar.id pada pendidik dan peserta didik. Metode dalam proses sosialisasi pemanfaatan akun belajar.id akan menggunakan metode konunikatif. Hasil dalam pengabdian ini dari tahap persiapan sosialisasi mulai mempersiapkan alat dan bahan serta materi, pengabdi juga memberikan modul yang dapat dipakai saat pengabdi tidak berada di lokasi pengabdian. Terdapat dua puluh tiga akun yang sudah aktivasi dan siap digunakan sebagai media belajar mengajar jarak jauh. Selama proses aktivasi akun pendidik lebih lancar karena pendidik sudah cukup memahami akun google, namun terdapat kendala dalam aktivasi akun peserta didik karena spesifikasi smartphone maupun kapasistas memori smartphone.
PENCEGAHAN KERUSAKAN EKOSISTEM LAUT DI SEKITAR PMBANGKIT LISTRIK TENAGA UAP (PLTU) BATANG DALAM PERSPEKTIF FIKIH LINGKUNGAN
Authors: Napitupulu Abdul Khaliq , Maysaroh NurAlinda Siti , Masduqi Fuad Hadziq , Zahra Alifian Nur , Fahreni Afna , Makfi Miqdam
Published: December 2022

Sudah banyak upaya pemerintah yang dilakukan untuk memutuskan rantai virus Covid-19, salah satunya adalah dengan upaya pemberian vaksinasi kepada seluruh masyarakat Indonesia. Tetapi terdapat sebuah komplikasi dalam hal ini, karena dalam vaksinasi ditemukan adanya pro dan kontra dalam masyarakat terhadap vaksin yang digunakan. Pro kontra tersebut adalah ditemukannya unsur babi dalam salah satu jenis vaksin, sehingga diperdebatkan kehalalan penggunaannya. Maka dari itu tulisan ini dibuat untuk meluruskan antara pro dan kontra yang sedang terjadi ditengah masyarakat Indonesia saat ini. Selain itu, tulisan ini bertujuan untuk mencari bagaimana konsep darurat yang digunakan untuk penerapan vaksin yang mengandung unsur dari babi di tengah masyarakat Indonesia yang mayoritasnya beragama Islam. Penelitian menggunakan metode penelitian kepustakaan (Library Research) yaitu jenis penelitian yang sumber datanya diperoleh dari kepustakaan. Jadi untuk memudahkan mencapai tujuan penulisan, penulis memfokuskan pada studi kepustakaan dan meneliti pada bahan-bahan yang telah tertulis. Penelitian dilakukan dengan cara membaca literatur yang berkaitan dengan masalah yang menjadi pembahasan. Hasil penelitian ini menyatakan bahwa keputusan DSN-MUI dalam memperbolehkan penggunaan vaksin AstraZeneca ini sudah tepat. Kebolehan/kemubahan ini disebabkan oleh aspek darurat yang ada saat kondisi pandemi ini. dalam kondisi pandemi Covid-19 ini setidaknya ada tiga aspek yang menyebabkan kondisi ini menjadi kondisi darurat, yaitu darurat makanan dan kesehatan, darurat al-‘usr wa umum al-balwa, dan darurat al-maradh.
Six-year-old Ecological Concrete in a Marine Environment: a Case Study
Authors: Kenny Amit , Ofer Rozovsky Ela
Published: December 2022

The durability of ecological concrete in a marine environment was studied. Specimens of a six-year-old submerged ecological concrete from a breakwater located in the East Mediterranean sea were analyzed for their biological carbonate deposition cover, chloride effective diffusion, carbonation, and mineralogy. About 57% of the surface was found to be covered by biogenic-deposited carbonates. The effective chloride diffusion coefficient and the carbonation rate were found to be reduced proportionally to the biogenic-carbonate cover. Most of the aluminates were found in non-crystalline minerals. No evidence of a sulfate attack was found.
Antioxidant and Antidiabetic Activity of Algae
Authors: Abo-Shady Atef Mohamed , Gheda Saly Farouk , Ismail Gehan Ahmed , Cotas João , Pereira Leonel , Abdel-Karim Omnia Hamdy
Published: December 2022

Currently, algae arouse a growing interest in the pharmaceutical and cosmetic area due to the fact that they have a great diversity of bioactive compounds with the potential for pharmacological, cosmetic, and nutraceutical applications. Many of these bioactive compounds are secondary metabolites whose amounts in the algae vary with varying environmental conditions. Free radicals and other active oxygen derivatives are recognized as a natural by-product of aerobic metabolism. However, reactive oxygen species directly participate in mechanisms related to various pathological states such as cancer, diabetes, atherosclerosis, Alzheimer's, and Parkinson's, among others. Diabetes mellitus (DM) is a metabolic disease resulting from changes in glucose metabolism and/or deficient production/action of insulin. This review has as its main objective to reveal the potential antioxidant and antidiabetic capacity of algae extracts.
Metformin Therapy and Breast Cancer Incidence in the Hail Region
Authors: Osman Mhdia , Muqbel Taif , Alenzi Ahad , Alenzi Shuruq , Kalifa Nasrin , Khojali Weam , Elagib Halima Mustafa
Published: December 2022

Metformin is a drug used to treat patients with type 2 diabetes, especially those who suffer from obesity. It is also used in treating women with polycystic ovary syndrome (PCOS). This disease has been shown to be related to insulin resistance and multiplied blood sugar ranges. Further, it has been found that using metformin improves these women's menstrual cycles and ovulation rates. Methods: A structured questionnaire will be conducted to determine the prevalence of breast cancer among women using metformin in the Hail region. Result: The incidence of breast cancer among women using metformin in the Hail region is very low. Conclusions: According to previous findings, metformin has been linked to lower breast cancer risk in women with type 2 diabetes. Furthermore, the findings of this study have corroborated the literature for the same by indicating a substantial connection between metformin use and a lower risk of breast cancer in women with type 2 diabetes.
KDEL Receptor Trafficking to the Plasma Membrane is Regulated by ACBD3 and Rab4-GTP
Authors: Tan Chuanting , Du Yulei , Zhu Lianhui , Jing Shuaiyang , Gao Jingkai , Yue Xihua , Qian Yi , Lee Intaek
Published: December 2022

KDEL receptor-1 maintains homeostasis in the early secretory pathway by capturing and retrieving ER-chaperones to the ER during heavy secretory activity. We have previously shown that a Golgi scaffolding protein (ACBD3) facilitates KDEL receptor localization at the Golgi via regulating cargo wave-induced cAMP/PKA-dependent signaling pathway. Unexpectedly, a fraction of the receptor is also known to reside in the plasma membrane as a stress response, although it is largely unknown exactly how KDEL receptor gets exported from the Golgi and travels to the PM. In this study, we sought to investigate the mechanism by which KDEL receptor gets exported from the Golgi en route to the PM and identified two crucial factors that greatly influence post-Golgi trafficking of KDEL receptor. We show here that ACBD3 depletion results in significantly increased trafficking of KDEL receptor to the PM via Rab4-positive tubular carriers emanating from the Golgi. Expression of constitutively activated Rab4 mutant (Q72L) increases surface expression of KDEL receptor up to 2~3-fold, whereas expression of GDP-locked Rab4 mutant (S27N) inhibits KDEL receptor localization to the PM. Importantly, KDELR trafficking from the Golgi to the PM is independent of PKA- and Src Kinase-mediated mechanism. Taken together, these results reveal that ACBD3 and Rab4-GTP are key players at the Golgi in regulating KDEL receptor trafficking to the cell surface.
A tale of three fluids: Fluid-inclusion and carbonate clumped-isotope paleothermometry reveals complex dolomitization and dedolomitization history of the Latemar platform
Authors: Mueller Mathias , Walter Benjamin F. , Swart Peter K. , Jöns Niels , Jacquemyn Carl , Igbokwe Onyedika A. , Immenhauser Adrian
Published: December 2022

This work focuses on an exceptionally complex natural laboratory, the Triassic Latemar isolated platform in the Dolomite Mountains of northern Italy. It explores spatial and temporal gradients in processes and products related to contact metamorphism, dolomitization, and the dedolomitization of marine limestones. Rock samples were studied using dual fluid-inclusion thermometry and clumped-isotope thermometry. Independent of the spatial position at Latemar, Δ47 clumped-isotope and fluid-inclusion data provide contrasting paleotemperature estimates. An apparent lack of systematic patterns in fluid-inclusion data (homogenization temperature, salinity, density) results from analyses of micrometer-sized growth zones within a single crystal. The composition of the individual fluid inclusions represents a “snapshot” of fluid mixing with variable endmember elemental ratios. The bulk crush-leach data and slopes in Caexcessversus Nadeficit diagrams indicate different water–rock interactions and fluid signatures with evaporation sequences and crystalline rocks. The presence of three fluid types (crystalline basement brine, halite-dissolution brine, seawater) in all carbonates suggests that all fluids coexisted during contact metamorphism and dolomitization of Latemar carbonates. Non-equilibrium processes overruled thermodynamic controls on the precipitation of diagenetic phases. Fluid mixing resulted in the precipitation of two complex carbonate successions. The Δ47 data represent bulk temperatures, averaging the mixing ratio of fluids with different temperatures and their respective volume. Fluid-inclusions record patterns of remarkable complexity and shed light on the complexity of a multi-fluid system. Data shown here provide answers to the controversial interpretation of dolomitizing fluid temperature in the Latemar and exemplify the strengths of multi-proxy paleotemperature studies.
LGBTQIA+ cartographies in filmic Madrid: narrative traits of spatial characterization
Authors: Álfeo Juan Carlos , Deltell Escolar Luis
Published: December 2022

Cartografías cinematográficas LGBTQIA+ en el Madrid fílmico: rasgos narrativos de caracterización espacial
En este trabajo se analiza el repertorio espacial y sus rasgos dominantes como fuente de caracterización indirecta de los personajes LGTBQI+, estudiando su representación en largometrajes de ficción localizados en Madrid y su provincia y exhibidos en el circuito comercial. La metodología que sirve de base al estudio es de tipo cualitativo, fundamentalmente, y es un desarrollo propio de los autores inspirado en el análisis de marcas narrativas de Hamon, concepto redefinido, a su vez, por Chatman como rasgo narrativo y en el estudio de los espacios diferenciales y los modelos de Casetti y di Chio. El objetivo fundamental es el de precisar, en suma, qué espacios componen el universo narrativo LGTBQI+, es decir, la cartografía cinematográfica que el cine elabora y propone para cada grupo de personajes en la Comunidad de Madrid y, ya que se ha constatado que no todos ellos han recibido el mismo tratamiento ni han sido representados con el mismo detalle y extensión, cuáles son sus rasgos diferenciales.
Spanish cities as filming locations: analysis and spatial distribution
Authors: Gámir Orueta Agustín , Montecino Huedo Patricia , Reyes Corredera Sergio
Published: December 2022

The main objective of this article is to show the spatial distribution of Spanish cities according to the degree of their cinematographic projection. For this purpose, a sample consisting of 178 feature films was selected. After viewing each of them, 3,071 exterior clips from these movies were geo-localized. Using this methodology has enabled us to circumvent the feature film as a unit of analysis, and instead focus attention on the clips, understood as such as sequences shot in exteriors, with their precise duration and geo-localization. The article describes and differentiates between three large territorial areas for filming: the Autonomous Regions of Madrid, Spain’s coastal cities, and Spain’s interior cities, examining factors that explain the distribution of the shootings, whether geographic, cinematographic or administrative-economic. Information from the highest-rated movies reveals a group of Spanish cities with limited cinematographic dissemination, for which some recommendations are made for improving the projection of the city’s image.
Pemanfaatan Limbah Kulit Jeruk sebagai Fortifikan Guna Memperkaya Nilai Gizi pada Cokelat
Authors: Mustafidah Roufi'ul , Asyari Rizki Putri , Velayati Jihan Maghfiroh , Sayekti Titah
Published: December 2022

Jeruk merupakan salah satu komoditas buah-buahan yang memiliki banyak manfaat bagi kesehatan manusia. Kecamatan Pulung merupakan penghasil jeruk keprok Pulung yang menjadi salah satu komoditas unggul di daerah Ponorogo. Namun, pemanfaatan jeruk hanya bagian daging buahnya saja sedangkan bagian kulitnya dibuang. Kulit jeruk yang dianggap sebagai limbah ternyata dapat dikonsumsi dan memiliki berbagai kandungan seperti antioksidan dan mineral seperti kalsium, selenium, mangan, seng, dan vitamin (C, A, B-kompleks) beberapa kali lipat dari pulpnya. Adanya berbagai kandungan tersebut menjadikan kulit jeruk layak dimanfaatkan menjadi berbagai macam olahan pangan yang variatif, lezat, dan bermanfaat bagi kesehatan. Salah satu camilan yang digemari semua kalangan adalah cokelat. Penelitian ini bertujuan untuk membuat cokelat kulit jeruk sebagai camilan yang memiliki nilai gizi. Penelitian ini menggunakan metode deskriptif kuantitatif. Data didapatkan dari hasil uji kandungan gizi dan berbagai referensi yang  berkaitan dengan permasalahan yang dibahas. Hasil penelitian ini menunjukkan bahwa dalam Cokelat Kulit Jeruk (CULUK) berpotensi untuk diproduksi sebagai salah satu alternatif camilan yang lezat dan sehat yang memiliki kandungan protein, lemak dan karbohidrat. Selain itu, 100 gram CULUK mengandung 29.24% antioksidan dan 13.37% vitamin C. Dengan demikian, fortifikasi kulit jeruk dalam pembuatan cokelat dapat meningkatkan nilai guna kulit jeruk dan sekaligus menambah nilai gizi dari olahan cokelat itu sendiri.
Terampil Membuat Kesimpulan Melalui Model Inkuiri Berbasis Science Education for Sustainable Development
Authors: Hani'ah Roudhotul , Fadly Wirawan
Published: December 2022

Perkembangan dalam ranah pendidikan saat ini lebih menuntut peserta didik untuk berperan aktif. Keterampilan proses siswa  berperan penting dalam hal ini, salah satunya yaitu keterampilan menyimpulkan. Tujuan penelitian ini yaitu untuk mengetahui apakah model inkuiri dengan pendekatan SESD lebih efektif dari pada model konvensional dalam meningkatkan kemampuan membuat kesimpulan peserta didik. Metode yang digunakan dalam penelitian ini yaitu kuantitatif true experimental dengan desain pretest- posttestcontrol group desaign. Sampel dalam penelitian ini yaitu peserta didik MTs Darul Huda kelas VII T (eksperimen) berjumlah 31 orang dan kelas VII Z2 (kontrol)  berjumlah 28 orang. Adapun analisis data menggunakan deskriptif kuantitatif, serta pengumpulan data yakni berupa observasi dan soal tes. Hasil penelitian menjunjukkanbahwa indikator membuat kesimpulan dengan pencapaian tertinggi yaitu membuat kesimpulan secara deduktif dengan nilai N- gain 0,71 termasuk kategori tinggi. Sedangkan membuat kesimpulan secara induktif menjadi indikator dengan ketercapaian terendah dengan nilai N- gain 0,46 termasuk kategori sedang. Dari hasil analisis data, dapat disimpulkan  model inkuri dengan pendekatan SESD lebih efektif dalam meningkatkan kemampuan membuat kesimpulan peserta didik.
Peningkatan Kualitas Multisektoral Melalui Budidaya Hidroponik untuk Kesejahteraan Masyarakat di Desa Tatung Kecamatan Balong Kabupaten Ponorogo
Authors: Agusta Fauji , Mizani Zeni Murtafiati , Suroso Joko
Published: December 2022

Tatung adalah sebuah desa di Kabupaten Ponorogo Jawa Timur yang terletak di Kecamatan Balong. Melalui hasil dari pemetaan serta penelusuran wilayah, Desa Tatung memiliki berbagai potensi serta aset yang bisa di kembangkan selama kegiatan Kuliah Pengabdian Masyarakat (KPM). Dari berbagai sektor yang ada, sektor pertanian menjadi aset potensi yang paling tinggi dibandingkan aset potensi lainnya. Karena bertani merupakan sumber pendapatan utama bagi sebagian besar masyarakat. Namun, sangat disayangkan dengan adanya pandemi COVID-19 banyak sektor yang terkena dampaknya, terutama pada sektor ekonomi. Masyarakat banyak yang kehilangan pekerjaan dengan kebutuhan pangan yang harus selalu terpenuhi. Untuk mengatasi permasalahan yang ada di Desa Tantung diperlukan kreativitas agar dapat mencapai kesuksesan. Maka kami peserta Kuliah Pengabdian Masyarakat di Desa Tatung berupaya memberikan solusi kepada masyarakat dalam meningkatkan kebutuhan pangan maupun ekonomi masyarakat di masa pandemi dengan pelatihan budidaya hidroponik. Dengan adanya pelatihan budidaya hidroponik diharapkan dapat meningkatkan pengetahuan dan ketrampilan masyarat, juga bisa membantu meningkatkan kualitas multisektoral ekonomi masyarakat melalui pelatihan budidaya hidroponik.
Peningkatan Kemampuan Berpikir Kreatif Melalui Penerapan Model Inkuiri dengan Metode Demonstrasi
Authors: Shima Silvia Nazahatul , Hadi Sofwan
Published: December 2022

Penelitian ini bertujuan untuk meningkatkan kemampuan peserta didik dalam berpikir kreatif melalui pembelajaran yang menerapkan model Inkuiri dengan metode Demonstrasi. Kemampuan berpikir kreatif peserta didik sangat berpengaruh terhadap pola pikir peserta didik dalam menyelesaikan permasalahan di masa yang akan datang. Metode penelitian ini menggunakan pendekatakan kuantitatif dengan desain Quasi Experimental. Teknik pengambilan sampel menggunakan Cluster sampling dengan jenis penelitian nonequivalent control group design. Jumlah sampel dalam penelitian ini yaitu 57 peserta didik. Teknik pengambilan data menggunakan posttest. Hasil penelitian menunjukkan keterlaksanaan pembelajaran dan aktivitas peserta didik dalam kategori baik. Hasil uji-t Two Tailed didapatkan hasil bahwa terdapat perbedaan kemampuan berpikir kreatif kelas yang menerapkan model Inkuiri dengan metode Demosntrasi dan kelas yang tidak menggunakan model dan yang menerapkan model konvensional. Hasil uji-t One Tailed didapatkan hasil rata-rata kemampuan berpikir kreatif kelas yang menerapkan model Inkuiri dengan metode Demosntrasi lebih tinggi dibandingkan kelas yang menerapkan model konvensional.
Community-based Zigzag Piloting Algorithm for the Strong Generalized Minimum Label Spanning Tree Problem
Authors: LONG Hao , Li Xiao-xia , LONG Zhu-ming , Wu Fu-ying
Published: December 2022

Edge-labeled graph (ELG) is an important abstract model of many practical applications, in which each edge is associated with one or more labels. Searching the minimum label spanning tree (MLST) of ELG is an important issue and proved NP-hard. In the last decade, researchers have put forward some algorithms, however, high computational cost and lower searching effectiveness are still the main obstacles, especially for large-size graphs. In this paper, we propose a heuristic to solve the strong generalized MLST problem (SGMLSTP). We decompose the SGMLSTP into two sub-problems, one is to search a sub-graph containing one or more spanning trees with the minimum labels from the original graph, and another is to search a spanning tree from the acquired sub-graph. As the latter sub-problem is already solved effectively, we focus on the former sub-problem and propose a community-based zigzag piloting algorithm: Firstly a weighted label graph is derived from the edge-labeled graph; then the label graph is partitioned and label communities are chosen in combination to form the initial solutions; finally, the zigzag piloting process is applied to make the initial solutions feasible and refined, of which the optimum one has the least labels. Label partition largely reduces the computation cost of searching the initial solutions, the zigzag piloting process help increase searching effectiveness, and experimental results on typical benchmark datasets fully verify this point and show better effectiveness and performance than that of the state-of-the-art algorithms.
Intracellular BAPTA directly inhibits PFKFB3, thereby impeding mTORC1-driven Mcl-1 translation and killing Mcl-1-addicted cancer cells
Authors: Sneyers Flore , Kerkhofs Martijn , Welkenhuyzen Kirsten , Shemy Ahmed , Voet Arnout , Eelen Guy , Dewerchin Mieke , Tait Stephen , Ghesquière Bart , Bootman Martin , Bultynck Geert , Speelman-Rooms Femke
Published: December 2022

Intracellular Ca2+ signals control several physiological and pathophysiological processes. The main tool to chelate intracellular Ca2+ is intracellular BAPTA (BAPTAi), usually introduced into cells as a membrane-permeant acetoxymethyl ester (BAPTA-AM). We previously demonstrated that BAPTAi enhanced apoptosis induced by venetoclax, a Bcl-2 antagonist, in diffuse large B-cell lymphoma (DLBCL). These findings implied a novel interplay between intracellular Ca2+ signaling and anti-apoptotic Bcl-2 function. Hence, we set out to identify the underlying mechanisms by which BAPTAi enhances cell death in B-cell cancers. In this study, we observed that BAPTAi alone induced apoptosis in lymphoma cell models that were highly sensitive to S63845, an Mcl-1 antagonist. BAPTAi provoked a rapid decline in Mcl-1 protein levels by inhibiting mTORC1-driven MCL-1 translation. Overexpression of nondegradable Mcl-1 rescued BAPTAi-induced cell death. We further examined how BAPTAi diminished mTORC1 activity and found that BAPTAi impaired glycolysis by directly inhibiting 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) activity, an up to now unkown effect of BAPTAi. All aforementioned effects of BAPTAi were also elicited by a BAPTAi analog with low affinity for Ca2+. Thus, our work reveals PFKFB3 inhibition as an unappreciated Ca2+-independent mechanism by which BAPTAi impairs cellular metabolism and ultimately the survival of Mcl-1-dependent cancer cells. Our work has two important implications. First, direct inhibition of PFKFB3 emerged as a key regulator of mTORC1 activity and a promising target in the treatment of Mcl-1-dependent cancers. Second, cellular effects caused by BAPTAi are not necessarily related to Ca2+ signaling. Our data support the need for a reassessment of the role of Ca2+ in cellular processes when findings were based on the use of BAPTAi.
Decoupling of land use net carbon flux, economic growth, and population change in China
Authors: Huang Xianke , Huang Yujie , Li Ruiliang , Cheng Wei , Su Yang , Li Feng , Du XianXiang
Published: December 2022

In the process of China’s modernization, promoting the sustainable development of resource-based cities is a major strategic issue and it has now also become a worldwide issue. This study uses the coupling model to validate the coupling relationship between China’s land-use net carbon flux and economic growth and population change during 2009–2017. The study for the first time draws the conclusion that the coupling degree among the three is getting lower, the correlation is gradually weaker, and the independent relationship is becoming more and more prominent. Utilizing the Tapio decoupling model, we obtained the weak decoupling conclusion that the economic growth rate is higher than the growth rate of the land-use net carbon flux, while negative decoupling of sprawl where the rate of population growth is less than the rate of net land use carbon flux growth.
Decadal Indian Ocean influence on the ENSO-Indian summer monsoon teleconnection is mostly apparent
Authors: Bódai Tamás , Aneesh Sundaresan , Lee June-Yi , Lee Sun-Seon
Published: December 2022

“Decadal influence” on the El Nin ̃o–Southern Oscillation-Indian summer monsoon (ENSO-ISM) teleconnection has been much studied but with plurality and ambiguity about the concept of influence. Here we provide formal definitions of the apparent influence of a specific factor on the teleconnection, as correlation coefficients, which enable us to test them as null-hypotheses. Using the recently released Community Earth System Model v2 Large Ensemble data, we show that a 50% chance for the detection of the apparent Indian Ocean influence under stationary conditions might take 2000 years of data. However, we find that this influence is mostly apparent indeed, as it originates from fluctuations of the decadal apparent moving window – as opposed to stationary climatological – ENSO variability, which causally influences an Indian Ocean Dipole-like apparent mean state. We also show that unattributed so-called “decadal influence”, defined as a deviation from a linear regression model of the teleconnection as a null-hypothesis, cannot be detected in 20th c. observations in South Asia even regionally. However, as a new insight, we find our new simple influence concept as a significant correlation coefficient to be possibly consistent with such a null-hypothesis.
The Role of Communities and Leadership in Ending Female Genital Mutilation in Tanzania: an Exploratory Cross-sectional Qualitative Study in Tanga
Authors: Mkuwa Serafina , Sempeho Jane , Kimbute Omari , Mushy Stella Emmanuel , Ndjovu Anthony , Mfaume Juhudi , Ngalesoni Frida
Published: December 2022

Background
Female genital mutilation (FGM) is one of the diehard cultures in the Mediterranean and sub-Saharan Africa. The act involves chopping off part of the female genitals in varying degrees depending on the society. The motive behind this practice includes reducing female sexual desire and as a sign of maturation. The current study explored the roles of community members and leaders in the fight against FGM; and the reasons for continuing the practice in some societies.
Method: We did an exploratory cross-sectional qualitative study between June – July 2020 in six purposively selected villages from Kilindi and Handeni districts in Tanga that were part of the ten years of implementation of the project. Ethnic leaders and village members aged 19 years and above were purposively selected. Due to the sensitive nature of the study, FGDs were conducted separately between men and women. In addition, we did the inductive thematic analysis.
Results: Four main themes emerged from the analysis; (1) history of FGM and reasons behind persistent FGM practices, (2) Challenges to abandonment of FGM, (3) strategies to be used to eradicate FGM, and (4) Key change agents in ending FGM. It was reported that the FGM practice was inherited from elders years ago and is believed to reduce women's sexual desire when the husband travels away for a long time. Some societies still practice FGM but secretly because for them marrying an uncircumcised girl is a curse as the husband and children will die. Some older women still practice FGM as they still hold the ancient culture. Constant communication with community leaders, seniors, and the young generation on complications of FGM will fasten efforts toward eradicating FGM practice.
Conclusion
There are sporadic cases done secretly associated with FGM practice since the ant-FGM campaign, so this should be the reason to continue with the campaign. Winning the tribal/ethnic leaders can facilitate better achievement in the fight against FGM. In addition, social diffusion with inter-tribe marriages was also singled out as one of the factors that will make FGM practice unfamiliar to the communities in the future.
Statistical analysis of the landslides triggered by the 2021 SW Chelgard earthquake (ML=6) using an automatic linear regression (LINEAR) and artificial neural network (ANN) model based on controlling parameters
Authors: Vanani Ali Asghar Ghaedi , Eslami Mohamad , Ghiasi Yusof , Keyvani Forooz
Published: December 2022

This study uses automatic linear regression (LINEAR) and artificial neural network (ANN) models to statistically analyze the area of landslides triggered by the 2021 SW Chelgard earthquake (ML = 6) based on controlling parameters. We recorded and mapped the number of 632 landslides into four groups (based on the Hungr et al. 2014): rock avalanche-rock fall, debris avalanche-flow, rock slump, and slide earth flow-soil slump using field observation, satellite images, and remote sensing method (before and after the earthquake). The results revealed that most landslides are related to debris avalanche-flow, rock avalanche, and slide earth flow under the disruption influence of slope structures in limestone and shale units and water absorption after the earthquake in young alluviums and terraces. The spatial distribution of landslides showed that the highest values of the landslide area percentage (LAP%) and of the landslide number density (LND, N/km2) occurred in the northern part of the fault on the hanging wall. The ANN models with R2 = 0.60-0.75 provided more accurate predictions of landslide area (LA, m2) than the LINEAR models, with R2 = 0.40-0.60 using multiple parameters. The elevation and slope were found to be the most influential parameters on the rock slump and the debris avalanche using ANN and LINEAR models. Aspect and elevation are the most important parameters for rock avalanches and rockfalls. The sliding earth flow and soil slump are most affected by the slope and elevation parameters. The peak ground acceleration (PGA) and the distance from the epicenter exhibited more effects on the LA than the intensity of Arias (Ia) and the distance from the rupture surface. Thus, the separation of seismic landslides using the classification of Hungr et al. (2014) can be helpful for predicting the LA more accurately and understanding the failure mechanism better.
State of E-Governance at Urban Local Government in Bangladesh: A Paradigm of Rajshahi City Corporation
Authors: Hasan Sabbir , Ullah S.M. Akram
Published: December 2022

The purport of this study is to depict the present scenario of e-governance at urban local government in Bangladesh. Rajshahi City Corporation (RCC), as a leading municipality in initiating and applying e-governance, has introduced almost ten e-services. After a deep exploration on RCC, it reveals that EBRIS and SARMS both the e-governance projections of RCC are successfully implemented presently. E-tender, e-nothi, e-death registration and web portals are also fairly implemented. And e-revenue and e-application are on the way to implementation. Contrarily, e-waste management, sms-based information service and smart rajshahi app are not implemented yet. The most realistic findings of this research are the unimproved ICT infrastructure, lack of proper IT training of the e-service providers, lack of cooperativeness of e-service receivers, lack of e-literacy of e-service receivers, intervention of third party and demanding bribe for providing e-services, harassment by e-service providers, lack of efficiency of e-service providers and lack of awareness of e-service receivers about e-governance. As an empirical research, it uses both the qualitative and quantitative methods. This study is an endeavor to present an overall current status of e-governance in RCC.
Flood Impact Assessment on Agricultural and Municipal Areas Using Sentinel-1 and 2 Satellite Images(Case study: Kermanshah province)
Authors: Gord Sadaf , Mavaddat Maryam Hafezparast , Ghobadian Rasoul
Published: December 2022

Flood is one of the most destructive natural events that can be investigated as soon as possible to reduce the extent of flood damage. Floods have caused adverse impacts on agricultural lands and settlements. RS is one of the most widely applicable and fast methods in this way. In this study, the S1A, SAR data with VH descending pass and S2 during 01/03/2019 to 20/03/2019 and 25/03/2019 to 20/04/2019 were used for the before and the post-flood period in Kermanshah province. MNDWI and NDWI were applied to detect the water zones of S2 and were compared and validate the S1 images. The quality of radar images is better than optical in flood conditions where the weather is cloudy and rainy. MODIS, Hydrosheds and SRTM satellite images were used as different filters to detect land use, permanent water and areas with slope of more than 5%. The results showed that totally 36,849 ha of lands are affected by the flood. It’s containing 7073 and 4224 ha of agricultural and urban lands that are exposed to destruction in this period. The NDWI and MNDWI indices were calculated flooded area as 30,179 and 32,540 ha, respectively which are lower values compared to the results of the S1.
Analysis of the Epidemiological Burden of intestinal obstruction in China 1990- 2019 Based on the Big Data of Global Burden of Disease Study (GBD)
Authors: Wu Junhong , Hou Zhibing , Chen Jiong , Zhao Hu , Zhang Zaizhong , Wang Yu , Lin Chengzhi
Published: December 2022

Background:A comprehensive assessment of the burden of intestinal obstruction was important in determining prevention strategies for the disease. We presented the trends in disease burden and its epidemiological features in China from 1990 to 2019 in order to provide a reference for the prevention of intestinal obstruction.
Methods: The GBD 2019 database was searched to obtain relevant data. The data we use included the prevalent cases, prevalence, incident cases, incidence, DALYs, DALY rate, and SDI for global and China. We analyzed the epidemiological age-period-cohort trend of intestinal obstruction in China from 1990 to 2019, and explored the relationship between the incidence and DALY rate and SDI.
Result: The incidence of intestinal obstruction in China increased in the last 30 years from 1990 to 2019, but the increase was not significant and remained stable in recent years. Among them, the incidence of 10-14 years youth group was the lowest, the incidence of 1-4 years infants’ group was higher, and the 85-89 years age group had the highest incidence, while the DALY rate decreased significantly with the obviously rise in SDI levels.
Conclusion: The disease burden of intestinal obstruction in China decreased to some extent from 1990 to 2019, which was negatively correlated with the level of social development. However, the prevention of intestinal obstruction in the elderly, infants and children still needs to be stepped up.