bluuebunny/crossref_metadata_2025 huggingface dataset:
Bioinformatic identification of proteins with altered PTM levels in a mouse line established to study the mechanisms of the development of fibromuscular dysplasia
Authors: Voronina A.I. , Miroshnichenko Yu.V. , Skvortsov V.S.
Published: September 2024

Data from a mass spectrometry experiment of a mouse line developed to study the mechanisms of fibromuscular dysplasia and deposited by d'Escamard et al. in ProteomeXchange (PXD051750) have been analyzed. Identification of peptides with post-translational modifications (PTMs) was repeated using more stringent conditions than in the original work. The following modifications were considered during analysis of changes in the PTM levels in experimental and control groups of mice: acetylation of lysine residue and N-terminal protein peptide, ubiquitination of lysine residue, phosphorylation of serine, threonine and tyrosine residues, and deamination of asparagine and glutamine residues. The multistage analysis resulted in selection of 23 proteins with PTMs for which different levels of modification between experimental and control groups could be assumed. These included six proteins with N-terminal protein acetylation, which were particularly interesting: P80318 (T-complex protein 1 subunit gamma), P43274 (Histone H1.4), P97823 (Acyl-protein thioesterase 1), P63242 (Eukaryotic translation initiation factor 5A-1), Q3UMT1 (Protein phosphatase 1 regulatory subunit 12C), Q9D8Y0 (EF-hand domain-containing protein D2). Thus, repeated bioinformatic analysis of the data deposited in the specialized databases resulted in detection of changes in the level of N-terminal acetylation of proteins that might be functionally significant in the mechanisms underlying the development of fibromuscular dysplasia.
A real-world observational study to evaluate the safety & effectiveness of Naftifine 2% cream in patients with superficial fungal skin infection
Authors: Chinda Monika , Godse Kiran , Vidya T S , Adhikari Pankaj , Prasad AK , Raj Chinmoy , Bhaskar Gaurav , Mapare Arjun , Jaiswal Ashok D
Published: September 2024

Naftifine hydrochloride, an allylamine, is a topical agent used in treating superficial fungal infections, especially dermatophytosis. The objective of this study was to assess the safety and effectiveness of naftifine 2% cream in Indian patients with superficial fungal skin infection.

A real-world observational study to evaluate the safety & effectiveness of Naftifine 2% cream in patients with superficial fungal skin infection.

It was an open-label, multi-centric, observational, prospective real-world study conducted on Indian patients, where subjects were advised to apply naftifine 2% cream on the affected area at the discretion of the treating physician. Effectiveness was determined by assessing the clinical cure (absence of signs and symptoms) and/or mycological cure (negative microscopic KOH test) at the end of the treatment. Safety & tolerability were evaluated based on the presence of adverse events and their severity. The patient compliance was recorded based on the investigator's assessment.

A total of 463 patients were enrolled in the study, out of which 82.07% achieved a clinical cure at the end of the treatment. The skin scraping for microscopic KOH mounting was available for 94 patients out of which the mycological cure was observed in 89 patients (94.6%) (p<0.0001) at the end of the treatment. Our study recorded a lower incidence of adverse events (2.4%), commonly including dermatitis, pruritis, skin irritation at the application site, and erythema. The reported adverse events were mild or moderate and were cured within 2-7 days. The naftifine 2% cream was well tolerated by 70.8% of the patients. Upon completion of the treatment, 296 patients (64.1%) exhibited 100% compliance to the study drug.

Topical Naftifine 2% cream was safe and effective in Indian patients with tinea cruris and tinea corporis.
A cross sectional study optimizing platelet rich plasma preparation using various centrifugation speeds and its effects on the platelet yield
Authors: Makwana Vaishali Sanket , Rachchha Zeal Jayeshbhai , Lathiya Sandip Labhubhai , Pandya Nehalben Manishbhai
Published: September 2024

Platelet-rich plasma (PRP) is an autologous preparation of platelets in concentrated plasma (with usually >1,000,000 platelets/μL or 2–7 times the concentration in whole blood), prepared by a process known as differential centrifugation. The therapeutic efficacy of a PRP preparation is largely determined by its platelet concentration. Although PRP has been used for many years, there is no standard preparation protocol. This study was conducted to compare different protocols to determine which spin variation produces the highest platelet yield.

A cross sectional study was conducted at a tertiary care hospital with 35 patients. We included the data of the patients that were enrolled in PRP therapy for various dermatological indications. We analysed the data for PRP prepared using different centrifugation protocols and then compared the platelet count of PRP with the baseline platelet count of whole blood to obtain the platelet yield. The platelet yields for different protocols were compared using statistical analysis (IBM SPSS software).

After comparing the platelet yield of different protocols, we observed that centrifugation at 1300rpm/246 g for 20 minutes followed by 1600 rpm/373 g for 20 minutes achieved the highest platelet yield-4.6468 times as compared to the mean platelet count in the whole blood and the difference was statistically significant.

Multiple parameters influence the platelet concentration obtained in PRP. Therefore, the practitioner must consider the method of PRP preparation that gives the optimum platelet yield to deliver the best therapeutic results to the patients.
Anhydrotic ectodermal dysplasia at tertiary care centre in western region of India
Authors: Rime Monica , Modha Jay Dhirajlal , Bhuptani Neela V , Patel Bharti K
Published: September 2024

Anhydrotic Ectodermal Dysplasia, a rare genodermatosis, results in developmental anomalies affecting structures derived from the ectoderm. This condition is characterized by a clinical triad encompassing hypodontia, hypotrichosis, and anhidrosis, alongside additional symptoms Anhydrotic.

We conducted a retrospective review of the medical records of patients diagnosed with Anhydrotic Ectodermal Dysplasia at the Department of Dermatology, PDU Govt Medical College and Hospital Rajkot over the duration of 14 years from june 2008 to june 2022 Clinical presentations, family history details, and the initial symptoms prompting medical attention were carefully documented.

In this case series,total 6 patients 5 males and 1 female of Anhydrotic Ectodermal dysplasia were identified. Clinical triad was present in all the patients. Family history was positive in 5 patient where 2 males were from the same family. Three patients were born out of consanguineous marriage.Initial presentations most commonly noted were intolerance to heat, recurrent fever, dry skin and abnormal dentition.

Anhydrotic Ectodermal dysplasia is a rare genodermatoses which is invariably characterized by its clinical triad. Early diagnosis is important in order to improve the quality of life.
Evaluating the use of an advance lotion for addressing skin hyperpigmentation
Authors: Choudhary Sanjay , Joshi Rajiv , Sen Dyotona
Published: September 2024

Localized hyperpigmented spots on the skin can cause concern due to their associated aesthetic implications. Skin types higher on the Fitzpatrick scale are particularly more susceptible to the development of hyperpigmentation. Several studies focusing on the pathophysiology of hyperpigmentation reveal that exposure to ultraviolet radiation can trigger or further exacerbate the condition. Many topical formulations are available in the market, consisting of either individual or a combination of agents. Of late, there has been an increased interest in botanical extracts as safer alternatives to traditional skin-brightening agents. However, there is a paucity of human trials evaluating the outcomes associated with such combination products.

This study examined the efficacy and safety aspects related to the use of Advance Lotion, which contains , licorice, kojic acid, arbutin, and vitamin E as key ingredients, for addressing skin hyperpigmentation.

The outcomes were evaluated using instrumental variables that are well-established indicators of skin pigmentation and based on self-assessment by study participants.

The results revealed a significant reduction in skin pigmentation and cumulative improvements upon the continued use of Advance Lotion. There were no associated cases of skin intolerance as observed in the clinical examination or reported by the study participants.

These promising results indicate the effectiveness of this product in visibly reducing pigmentation.
Acute necrotizing acral erythema associated with hepatitis C: Histopathological dermoscopic correlation
Authors: Vora Rita , Dhinoja Niraj , Pillai Devna , Jadav Kishan
Published: September 2024

Necrotizing acral erythema (NAE) is a rare disease associated with hepatitis C and is considered as diagnostic marker. Clinical findings are well-circumscribed hyperpigmented papules and thick adherent scaly plaques symmetrically distributed on the dorsum of the foot. From a clinical perspective, NAE shares similarities with other conditions such as necrotizing erythema migrans (NME), enteropathic acrodermatitis (AE), and pellagra. To clearly distinguish NAE from similar conditions, a better understanding of its causes and histopathological features is important. NAE often follows a pattern of worsening and improving symptoms. Dermoscopy is noninvasive and can be an important tool in differentiating NAE from other necrotizing erythema and aids in diagnosis. Oral zinc therapy is the most effective treatment method regardless of HCV infection. Here, we present rare case report of a 46-year-old male patient who presented with clear fluid bullae and surrounding erythema in the lower extremity due to HCV infection with improvement after oral zinc treatment.
A study of functional outcome of bimalleolar fracture with syndesmotic injury after open reduction and internal fixation in young adults
Authors: Thoudam Solemn , Sharma Yogesh , Garg Rahul , Das Samay , Kevadiya Milan , Gupta Aniket
Published: September 2024

Malleolar injuries when combined with syndesmotic injuries are widely regarded as some of the most common and severe fractures that affect the lower extremities. These injuries are of great significance because the ankle joint bears the weight of the body, making it prone to instability and difficulty in locomotion. Open reduction and internal fixation have become the preferred treatment option for the majority of unstable bimalleolar fractures, as this surgical method restores the ankle's anatomy, biomechanics, and contact loading characteristics.

Prospective study of 20 patients of bimalleolar fracture was done in MMIMSR, Mullana, Ambala who were surgically managed by TBW/screw for medial malleolus fixation and plating for fibula.

: According to Baird and Jackson scores, out of 20 cases 65% had good to excellent result, 55% had fair result and 10% had poor functional outcome

Achieving accurate anatomical reduction, restoring articular congruity, and timely surgical fixation using appropriate implants can lead to favourable functional outcomes.
Functional and radiological outcome of using proximal femoral nail for intertrochanteric fractures of femur among geriatric population in a tertiary care hospital: An evaluation study
Authors: Srinivasan Velmurugan , Pandiyan Saravana , Priya Hema
Published: September 2024

The intertrochanteric (IT) fracture of the femur is an extra-capsular fracture that occurs between the greater and lesser trochanters. The introduction of proximal femoral nailing (PFN) is one of the fixation modalities for proximal femoral fractures that has shown positive results with relatively lesser intraoperative complications and considerably low post-operative complication rates. Hence, this study intends to analyse the functional and radiological outcomes of proximal femur fractures surgically managed with Proximal Femoral Nail.

A prospective study was done among 45 patients above 65 years from June 2022 to June 2023. The functional outcome was measured by Harris Hip Score (HHS), the radiological outcome by the time of fracture union, and the pain scores by Visual Analogue Scale (VAS). Patients were followed up at regular intervals for 6 months post-surgery.

There were no post-operative complications observed. The average time of union was 18.5 (±4.1) weeks. The mean HHS and VAS Score at the end of 6 months was 86.978±4.0 and 0.4±0.49. The Comparison of mean VAS at different intervals was statistically significant. There was a significant association between age and VAS scores at 6 weeks, 3 months, and 6 months.

PFN has the advantage of requiring shorter exposure time and a lower likelihood of morbidity and operating time. Thus the treatment of intertrochanteric fracture with PFN has a more favourable outcome and it is one of the implants of choice for intertrochanteric fractures at present.
Effect of posterior femoral condylar offset (PCO) on clinical results of multi-radius (MR) femoral design implant/component in posterior stabilized total knee arthroplasty (PS TKA)
Authors: Patni Aaditya , Mahawar Deep Kunwar , Dodiyar Piyush
Published: September 2024

When a posterior condylar offset (PCO) is properly reconstructed in a Total Knee Arthroplasty (TKA), a larger posterior clearance can be achieved, which helps delay impingement posteriorly and maximizes the range of flexion (ROF). This study was conducted to investigate the effect of PCO on clinical outcomes using Multi-radius (MR) femoral design components in PS TKA.

This hospital-based prospective observational study was conducted between January 1, 2018, and December 31, 2018, with a 6-month follow-up. A total of fifty patients were operated on with a MR PS design. The PCO, flexion, and knee society scoring (KSS) system were measured preoperatively and postoperatively.

: The average age of the patients was 66.8 (range 58.3 to 75.3) years. The average preoperative and postoperative PCO was 27.5 (range 25.3 to 29.7) and 29.2 (range 26.2 to 32.2) mm, respectively. The average preoperative and postoperative non-weight-bearing flexion was 106.5 (range 93.7 to 119.3) and 119.9 (range 116.6 to 123.2) degrees, respectively. The average preoperative and postoperative weight-bearing flexion was 96.7 (range 86.6 to 106.8) and 123.6 (range 120.7 to 126.5) degrees, respectively. The average preoperative KSS knee score was 55.9 (range 52.6 to 59.2), and the average preoperative KSS function score was 29.4 (range 17.3 to 41.5). The average postoperative KSS knee score was 83 (range 80.5 to 85.4), and the average postoperative KSS function score was 83.2 (range 78.5 to 87.9). Among them, sixteen knees (32%) showed excellent KSS knee and function scores, while 34 knees (68%) showed good scores. There were statistically significant differences for all variables.

: There was a significant increase in PCO, flexion (both weight-bearing and non-weight-bearing), KSS knee score, and function scores.
Management and outcome of gap non-union of tibia by ilizarov ring fixator
Authors: Pandey Divyam , Sharma Jayant , Shukla Abhishek Kumar
Published: September 2024

Road traffic accidents are of growing public health importance worldwide, contributing significantly to the global disease burden. Associated bone tissue defect and infection, commonly result in development of infected non-union. Non-union of long bones especially tibia when associated with infection has always been a challenge to orthopaedic surgeons. Bony union is not usually contained until the infection has been eradicated and there are usually coexisting problems of deformity.

The objective of the study was, to evaluate Ilizarov fixator method in the treatment of gap non-union.

A descriptive study was conducted on 25 patients admitted in Orthopaedic Department of Index Medical College, Hospital & Research centre, Indore from November 2022 to February 2024. Pre operative & post operative x-rays were done in each case. Debridement followed by fixator assembly and Uni-focal or bi-focal osteotomy followed by transport was done.

Out of 25patients, 23 were male and 2 were female. The mean age of patients was 38years, with 60% being in 30-40years age group. The patients with grade II open fractures 11, grade IIIA were 6, grade I were 5 and patients with closed fracture were 3. Maximum of non-union were in the region of diaphysis and metaphysis. Our results showed that 76% of the patients has excellent or good results, of bone union. There were 48% excellent, 28% good, 16% fair and 08% poor functional results in our study. There were no failures in our study. Most common post-operative complications we came across is pin tract infection and equinus. Nearly all the complications were managed and outcome was good in these cases except for 2 cases wherein there were non-union, in which results were poor.

Ilizarov ring fixator is an excellent treatment modality for gap non-union of tibia, in terms of union.
Severe acinetobacter necrotizing fascitis following open reduction and tension band wiring for patella fracture: A case report
Authors: Naik Rajesh B , Kammar Sherashah F , Hosangadi Adiveppa A , Pawar Vinay
Published: September 2024

Necrotizing fasciitis (NF) is a rare form of bacterial infection that leads to necrosis of the fascia, skin, subcutaneous tissues and vasculature surrounding them; high mortality rate and morbidity make it a major concern. Here, a young male of 27 years who was previously healthy, came to the Emergency department for motor vehicle accident. It was determined that he suffered a closed transverse fracture of the left patella for which he undergoes open reduction and Tension band wiring. Post operatively a patient started with clinical image of necrotizing fasciitis like erythema, tenderness, blisters, and skin necrosis. Microbiological examination of the cultures unraveled that Acinetobacter species sensitive to meropenem. The patient was taken to the operation room for the fasciotomy and subsequently debridement of the wound was done to deal with the sepsis. Split skin graft was harvested and then placed on the wound site to facilitate the healing. At six month follow-up, the wound had closed adequately with a perfect outcome. An early diagnosis and a timely surgical debridement, the use of targeted antibiotic therapy, and the practice of vigilant wound care are essential strategy needed to prevent the complications and to see the best recovery.
BIDeconomics México: panorama de oportunidades
Authors: Filippo Agustín , Jiménez Miguel Angel
Published: September 2024

Este BIDeconomics, que propone distintas acciones y recomendaciones basadas en las mejores prácticas internacionales, es una contribución que hacemos a partir del conocimiento y la experiencia del Grupo BID, en búsqueda de un desarrollo más inclusivo y sostenible para México.
Promoting Technology Adoption in Schools: Preliminary Evidence from Peru
Authors: Arias Ortiz Elena , Cristia Julian P. , Malamud Ofer , Méndez Carolina
Published: September 2024

This paper investigates the effectiveness of different interventions to promote teacher adoption and sustained use of a Computer-Assisted Learning (CAL) platform in public schools in Lima, Peru. The study evaluates three strategies: schoolwide workshops, targeted workshops for selected teachers, and a combination of workshops and personalized coaching. Using a large-scale randomized controlled trial involving low-performing schools, we find that all strategies significantly increased teacher registration and initial student engagement with the platform. Teachers who participated in workshops exhibited more than double the registration rates compared to the control group, and those who received both workshops and coaching demonstrated higher sustained use, as evidenced by a greater share of students connecting regularly and completing exercises. Spillover effects were important. Non-treated teachers in treated schools use the platform significantly more than control teachers. However, platform use declined markedly one year post-intervention, highlighting the necessity for continuous support.
Optimización de la resistencia a la corrosión de recubrimientos de TiO2 anodizados mediante parámetros controlados de calcinación
Authors: Aperador-Chaparro William Alexander , Barba-Ortega José , Rincón- Joya Miryam
Published: September 2024

Estudiamos aquí cómo parámetros de calcinación como la temperatura y la duración influyen en la composición de fases y la resistencia a la corrosión de los recubrimientos de dióxido de titanio (TiO2) anodizados. Se sintetizaron las fases de anatasa y rutilo del TiO2 en superficies de titanio mediante anodización a 40 V, seguida de calcinación a 350 °C y 450 °C, respectivamente. Se utilizó la espectroscopía de impedancia electroquímica (EIS) para evaluar estas propiedades y comportamientos. Los resultados indicaron que los tiempos de calcinación más largos y las temperaturas más altas favorecieron la fase rutilo, en tanto que los tiempos más cortos resultaron en recubrimientos con una mezcla de anatasa y rutilo. La fase rutilo mostró una resistencia superior a la corrosión debido a una cristalización más completa y la reducción de defectos estructurales. El estudio subraya la importancia de optimizar los parámetros de calcinación para alcanzar las fases cristalinas deseadas y mejorar propiedades como la resistencia a la corrosión, con implicaciones prometedoras para aplicaciones en entornos corrosivos y sujetos a desgaste mecánico.
O poder (de) disciplinar: notas sobre o assédio como cavalo de Tróia na regulação jurídico-laboral
Authors: Oliveira Ana
Published: September 2024

Este artigo propõe-se explorar algumas características, manifestações e dilemas que acompanham a formação de um domínio de saber e de poder em torno do assédio. Partindo de uma aproximação sociojurídica ao universo judicial e ao governo da subordinação laboral, procurarei demonstrar de que modo a invocação e a regulação do assédio sexual contribuem para legitimar e expandir o poder disciplinar; convertendo-se, como figura no título do artigo, num cavalo de Tróia em diferentes contextos institucionais.
Ciberdemocracia e lei por iniciativa popular digital no Brasil: um estudo de caso do app “Mudamos
Authors: Dos Santos Marcelo Bidoia
Published: September 2024

Este trabalho rediscute a democracia direta no Brasil a partir da lei por iniciativa popular e suas potencialidades prometidas pelo surgimento das novas tecnologias de informação e comunicação. Para isso, partiu-se da democracia representativa e do histórico de utilização da iniciativa popular no país para, então, aprofundar-se no aplicativo “Mudamos”, desenvolvido pelo Instituto de Tecnologia e Sociedade do Rio, cuja finalidade é permitir a utilização digital da iniciativa popular através de smartphones. Doravante, foi feita pesquisa empírica qualitativa com técnicas de pesquisa de observação direta e participativa, e coleta documental. O estudo de caso foi método de procedimento com propósitos descritivos e exploratórios, objetivando perquirir a compatibilidade jurídica e tecnológica do app com a realidade brasileira. A conclusão, dada pelo método hipotético-dedutivo, sinalizou a existência de tal compatibilidade, mas com recomendações de aprimoramento.
Genre PRology and convergence of genres of PR text
Authors:   International Academy of Business and New Technologies (IBUNT), Stepanov Valentin N. , Krivonosov Aleksey D. ,   Saint Petersburg State University of Economics (SPbGEU)
Published: September 2024

In the basis of a special area of genre PRology as a branch of the science of public relations the authors put the criterion of the diversity of PR-information in multi-channel public communication via new media. As a subject of genre PRology, the authors consider convergence of information formats of a PR text in a multi-channel PR. In the genre revision of PR communication in social media, the genre transformations of PR texts are influenced by the following factors: 1) technological, 2) intentional, 3) structural. Technologically, PR texts functioning in the space of social networks are characterized by 1) a polycode structure, which implies the equivalence of verbal and non-verbal levels of meaning; 2) the transgressive nature of the publication, which determines the animation of the message and its transgression (movement) in the digital space. PR texts are multi-intentional in nature. Structurally, PR texts in social networks undergo three types of convergence: 1) structural or presentational, 2) discursive, and 3) genre. Structural, or presentational, convergence of PR texts in social media is associated with the allocation in the post structure of the presentation (the actual text and iconic materials) and the reaction (readers’ comments). Discourse convergence of PR-text is associated with 1) diffusion of institutional and intentional types of discourse, 2) inter-institutional discursive interaction (PR and advertising). Genre convergence of PR-texts is a genre symbiosis of three types – convergence of primary and secondary speech genres, convergence of primary simple genres of PR-text, and intermedial convergence.
Linguistic and cultural characteristics of the speech genre “wish”
Authors:   Pushkin State Russian Language Institute, Moscow State Linguistic University, Karasik Vladimir I.
Published: September 2024

The paper deals with the speech genre “wish” treated as emotional and volitive communicative event, its meaning is an expressed wish of implementation of something good or bad for somebody. Grammatically, this genre is a kind of mood named “optative”. It is a speech act describing a certain situation which implies an emotional reaction of a person. The reaction of an addressee for a good wish is usually expressed in words or gestures of gratitude. In case of a bad wish expressed directly it merges with a quarrel and a reverse bad wish. Common objects of good wishes are good health, happiness, prosperity, success and good luck. Good wishes may be combined with proactive criticism, accusation, reproach, or request. This speech act may be either neutral or discourse specific (used by soldiers, sailors, students, etc.), it is specifically used when addressed to elder people or applied to certain events, e.g. weddings. Bad wishes were initially pronounced as magic meant to bring harm to someone, and nowadays they are used as a kind of invectives or jokes. Bad wishes are usually combined with insult.
Analytical review of the USA in modern Russian Mass Media: Features of the genre structure (based on spatial metaphors)
Authors:   Saratov State University, Kirillova Kseniia I.
Published: September 2024

The article characterizes conceptual metaphors as one of the ways of structuring the genre of analytical review in modern Russian newspapers. The object of the study is spatial transfer models used by analysts (professional journalists and experts) to represent the image of the United States in the modern world. The research material consists of 138 spatial metaphors in 410 contexts extracted from 43 articles of six socio– political newspapers dating 2022–2023. The relevance of the topic is determined by the need to clarify the place of metaphors in modern mass media, which are undergoing significant changes both in genre-structural and linguistic aspects. The aim of the work is to identify the role of spatial metaphors in the conceptual representation of the United States in the genre of analytical review in modern Russian newspapers. Based on a comprehensive analysis using modern semantic, cognitive and discursive methods of textual material, it was found that in the genre under study spatial conceptual metaphors occupy an important place in the implementation of the main functions of the analytical genre – conceptual (logical-argumentative), evaluative and influencing. In particular, it is shown that in modern all-Russian newspapers, with the help of three basic models of spatial metaphorization (purposeful activity, being and development, systemic connections and relations), an integral image of the United States is formed as an active participant in global economic and socio-political processes, the main purpose of which is to assert its leadership position by subordinating allies and weakening opponents and competitors. The result of such actions is the growth of conflicts and general instability in the world.
Getting Your Scholarly Papers Published: A Guide on How to Avoid the Top Ten Most Common Causes of Paper Rejection
Authors: Adom Dickson
Published: September 2024

Scholarly writing and publishing are activities marked by intellectual honesty, integrity, and excellence. Together, they are an indispensable requirement for academics to maintain and sustain their careers in various academic institutions. However, in higher education institutions, the infamous aphorism 'publish or perish' has resulted in unethical academic practices. These practices derail the quality expected of scholarly writing and publishing. This paper is a collection of advice to novice writers on the ten most common reasons why scholarly papers are rejected, offering sound solutions to these problems. Though an unpleasant experience, scholarly paper rejection keeps authors on guard against unethical academic writing practices. It helps them to transform their scholarly papers to meet the high standards of academia. The paper contends that scholarly paper rejection is an important activity in scholarly writing and publishing because it ensures quality in academic knowledge production and dissemination.
Foreign Direct Investment And Labor In Brazil: An Econometric Analysis In The State Of São Paulo
Authors: Almeida Mateus C , de Carvalho Ana CG , Polloni-Silva Eduardo , Moralles Herrick F
Published: September 2024

The ability of FDI to spur economic modernization in the recipient economy has been widely acknowledged in the literature. Brazil stands out as the region that receives the most foreign investment in Latin America. Studies on the effects of FDI in Brazil are still in the early stages, though. The impact of FDI on the local labor market and the average worker income in the host region is examined in this study. To achieve this, we used the first regional-level FDI database in the nation and specifically examined the effects of FDI in the area with the highest industrial concentration: the state of São Paulo. This is the first study to examine while considering FDI in the area, the relationship between employment and income at the municipal level in the state of São Paulo. The findings support the claim that the presence of multinational corporations raises the standard of employment, particularly in fields that demand skilled labor. A favorable environment for FDI can leverage the economic and social development of host regions and support the formulation of local policies. This also emphasizes FDI as a vehicle for increasing employment and valuing the workforce, adding to the body of existing literature and supplying information for forthcoming research on the topic.
O bullying narrado por educadores de escolas de Ladário-MS: um “olhar” pela Teoria Crítica
Authors: Ferreira Isabella Fernanda , Freitas Nivaldo Alexandre de
Published: September 2024

Este artigo tem como objetivo apresentar os dados de uma pesquisa local sobre o bullying vinculada ao projeto de pesquisa “Violência Escolar: discriminação, bullying e responsabilidade”, de abrangência nacional e internacional, que contou com financiamento do CNPq. A pesquisa tem como referencial teórico a Teoria Crítica da Sociedade e alguns autores que investigam o bullying. Quanto ao método, trata-se de uma pesquisa de natureza qualitativa em que foram entrevistados doze professores que ministram aulas para o nono ano de duas escolas municipais. Os resultados indicam que poucos docentes identificam o bullying e reconhecem os agentes envolvidos, bem como têm dificuldade em pensar medidas para combatê-lo. Conclui-se que, embora haja avanços importantes no modelo de educação inclusiva, é preciso seguir na busca por elementos que envolvam os responsáveis pelo ensino em sala de aula na perspectiva da inclusão, o que inclui o enfrentamento a toda forma de violência escolar.
Laser Radiation to Stimulate Tobacco Growth
Authors: Mihaylova Emilia , Pashova Teodora , Drumeva-Yoncheva Marina , Keranova Nelly
Published: September 2024

Background: During the last 50 years the progress of chemical technology provoked a production revolution in agriculture. Many chemicals are used for fertilizing crops, controlling pests and helping to develop a highly successful farm system. The long-term use of chemicals in agricultural production resulted in a decrease in plant resistance, plant yield and soil-yielding capacity. The negative effects of chemicals on agricultural produce and the environment are commonly known. Therefore, many scientists believe that this century is the century of biophysical methods in agriculture. One biophysical method for plant growing stimulation is laser irradiation of seeds before sowing. Methods: The subjects of this study were three genotypes of Virginia tobacco, whose seeds were irradiated with a red laser (l=655 nm, P= 0,7 mW) with different durations (30s, 60s, 120s). The present study aimed to trace the period of seedling formation and to establish the effect of laser irradiation on the duration of the phenological growth stages. Mathematical and statistical processing methods are applied to the database of experimental data. Result: It was found that pre-sowing laser irradiation of tobacco seeds with a red laser led to an acceleration of germination. The results show that the wide application of pre-sowing laser irradiation of tobacco seeds will enable intense and more qualitative tobacco leaf production, as well as the protection of the environment.
Les maladies respiratoires chez les volailles en élevage intensif au Nigeria
Authors: Joshua R.A.
Published: September 2024

Une étude de l'épizootiologie des maladies respiratoires chez les volailles d'élevage intensifs a été menée dans quatre zones écologiques du Nigéria. La maladie respiratoire chronique sévissait dans les zones ecologiques étudiés . L'étiologie des maladies respiratoires est complexe par son interaction avec l'hôte qui provoque la maladie clinique ou la mort. Le taux de mortalité moyen était de 14,9 plus ou moins 6,7 dans les bandes infectées. L'infection était généralement plus sévère chez les jeunes que chez les adultes. On a observé une application inadéquate de la chimiothérapie. Différentes erreurs de gestion ont eu tendance à entraver l'action rapide du traitement et les mesures de prophylaxie.
Prophylaxie de la cowdriose et observations sur la pathologie ovine dans la région des Niayes au Sénégal
Authors: Gueye A. , Mbengue M. , Diouf A. , Vassiliades Georges
Published: September 2024

Des moutons provenant d'une zone indemne de cowdriose ont été immunisés par la méthode de l'infection, suivie du traitement par une oxytétracycline à longue durée d'action. Ces animaux sont ensuite exposés dans une zone d'enzootie à l'infection naturelle, en même temps que des moutons témoins. On observe l'évolution numérique des tiques infestant ces ovins, afin d'établir une corrélation entre l'infestation causée par certaines espèces, notamment par Amblyomma variegatum, et l'apparition de la cowdriose. Chez des animaux dont la mort est associée à l'ehrlichiose et à l'anaplasmose dans le lot des moutons immunisés contre la cowdriose, on observe, sur les frottis de cortex cérébral de certains animaux, des colonies de Cowdria ruminantium. Des interrogations subsistent donc sur la véritable nature de l'immunité engendrée par la cowdriose. Par ailleurs, ces pertes mettent en évidence la nécessité d'une approche intégrée pour la lutte contre la pathologie affectant le bétail dans une région. L'examen des espèces de tiques inféodées au cheptel indique la présence, dorénavant significative, de Rh. e. evertsi auparavant absente de cette région.
Observation sur l’ecthyma contagieux du dromadaire (Camelus dromedarius) au Soudan
Authors: Ali O.A. , Kheir S.A.M. , Abu Damir H. , Barri M.E.S.
Published: September 2024

Les symptômes et la pathologie de l'ecthyma contagieux des chamelons au Soudan ont été étudiés. Les animaux manquaient d'appétit, étaient amaigris et légèrement anémiés. La maladie s'est manifestée par des lésions cutanées autour des lèvres et des naseaux. Dans quelques cas, la jonction entre la peau et la muqueuse était concernée. Au point de vue pathologique, on note l'apparition de vacuoles dans les couches épithéliales. Les zones concernées étaient le siège de lésions ulcératives et d'hémorragies et une surinfection bactérienne secondaire était fréquente. Le microscope électronique s'est révélé très utile pour un diagnostic différentiel rapide.
Description d’un protocole pour l’isolement et l’identification de Clostridium perfringens et des bactéries apparentées
Authors: Abdel Salam I.S. , El Sanousi S.M.
Published: September 2024

Les propriétés de 220 souches de Clostridium perfringens et des bactéries assimilées ont été étudiées. Les auteurs décrivent le protocole mis au point pour leur isolement et leur identification. Il est fondé sur la présence ou l'absence d'une enzyme, la lécithinase, sur l'hémolyse synergique avec la toxine de Streptococcus groupe B et l'inhibition de ces souches en présence des antisérums appropriés et leur réaction en milieu "lactose, gélatine, nitrate, mobilité (LGNM)" accompagné de la fermentation de certains sucres.
Développement et survie d'Haemonchus contortus d'origine ovine sur parcelle à Bunia (Ituri, Zaïre)
Authors: Chartier C.
Published: September 2024

Le développement et la survie des larves d'Haemonchus contortus ont été étudiés entre décembre 1987 et novembre 1988 à trois périodes différentes (saison sèche, première et seconde saisons des pluies) sur une parcelle infestée expérimentalement, à Bunia (Ituri, Zaïre). Quelle que soit la saison, le développement des larves infestantes dans les fèces est rapide (6 jours) et le maximum de larves dans l'herbe est rencontré entre le 12e et le 18e jour après les dépôts. Cependant, les deux saisons pluvieuses sont plus favorables aux infestations des animaux, à la fois par l'obtention d'un nombre élevé de larves sur le pâturage et par une survie accrue de ces larves au bout de quatre semaines.
Influence de la castration partielle et totale sur les paramètres de reproduction des béliers Poulfouli de l'extrême Nord du Cameroun
Authors: Thys Eric , Bister J.L. , Paquay R. , Hardouin Jacques , Verhulst A.
Published: September 2024

La circonférence scrotale, l'aspect macro- et microscopique des testicules, les concentrations plasmatiques des hormones gonadotropes LH et FSH et celles de la testostérone ont été étudiés lors de deux expériences de castration partielle et totale effectuées sur des béliers Poulfouli du Cameroun, abattus à 15 mois. La mesure de la circonférence scrotale permet de suivre l'involution testiculaire chez les béliers castrés à la pince de Burdizzo. Cette involution ne se stabilise que tardivement. Aucune influence saisonnière n'est observée chez les béliers entiers. La fonction exocrine (spermatogénèse) comme la fonction endocrine (production de testostérone) sont totalement supprimées chez les castrés à la pince. Le poids des testicules des béliers castrés partiellement par la méthode du "short scrotum" est très variable (76,1 + ou - 41,78 g) ainsi que la suppression de la spermatogénèse. En revanche, les taux de testostérone sont proches de ceux des béliers entiers et expliquent vraisemblablement les performances zootechniques observées antérieurement. Les auteurs concluent que, si la castration partielle constitue une alternative intéressante du point de vue zootechnique, il faut rester prudent dans la suppression du pouvoir fécondant chez les castrés par le short scrotum.
Distribution de la translocation robertsonienne 1/29 chez les bovins trypanotolérants et les zébus de Côte-d'Ivoire
Authors: Cribiu E.P. , Meyer Christian , Yesso P. , Durand V. , Popescu C.P.
Published: September 2024

L'analyse chromosomique d'une population bovine de Côte-d'Ivoire a permis de détecter la translocation robertsonienne 1/29 dans les races trypanotolérantes Baoulé, Ndama et parmi les Zébus. Si le chromosone Y est toujours acrocentrique chez les Zébus, en revanche, chez les taureaux Baoulé et Ndama, il est soit métacentrique, comme chez Bos taurus, soit plus rarement acrocentrique, ce qui pourrait indiquer un métissage avec des zébus.
Aspects économiques de l'application de la castration partielle ou totale sur les béliers Poulfouli de l'extrême Nord du Cameroun
Authors: Thys Eric , Hardouin Jacques , Verhulst A.
Published: September 2024

Dans le cadre de l'étude de l'influence de la castration totale ou partielle sur les performances des béliers Poulfouli de l'extrême nord du Cameroun, une analyse économique des coûts d'exploitation est effectuée et les résultats comparés avec des données commerciales recueillies sur les marchés du département du Diamaré. Le but est de déterminer si l'application de la castration en embouche est économiquement avantageuse pour le producteur. Cette analyse montre qu'une plus-value est obtenue par rapport au marché en castrant les béliers mais qu'elle ne compense pas les coûts d'exploitation qu'entraîne cette catégorie d'animaux par suite d'une alimentation plus coûteuse que celle des béliers entiers. En outre, les animaux castrés sont commercialisés significativement plus tard que les entiers, ce qui immobilise plus longtemps le capital. Il faut donc formuler des réserves en matière de promotion de la castration totale, du moins en ce qui concerne les bénéfices que peut en tirer l'éleveur pour l'engraissement. La castration partielle par la technique du short scrotum semble une méthode de production économiquement plus intéressante.
Compétence vectorielle des lignées Bobo-Dioulasso et Maisons-Alfort de Glossina palpalis gambiensis Vanderplank 1949 infectées simultanément par Trypanosoma brucei brucei EATRO 1125
Authors: Kazadi J.M. , Kageruka P. , Losson Bertrand , Van Hees J.
Published: September 2024

L'étude a concerné la compétence vectorielle (CV) de 1 257 mouches ténérales des deux lignées parentales Bobo-Dioulasso (BD) et Maisons-Alfort (MA) appartenant à Glossina palpalis gambiensis. Les individus de ces lignées ont été nourris une fois et simultanément sur un cobaye infecté par Trypanosoma brucei brucei EATRO 1125. Ils ont été dissèques après un entretien de 33 jours sur des cobayes sains. L'analyse statistique des résultats n'a pas montré de différence significative d'indice procyclique entre les mâles et les femelles de la lignée BD. Par contre, cet indice a été plus marqué chez les mâles que chez les femelles de la lignée MA. L'indice procyclique des mâles de la lignée MA a été plus élevé que celui des mâles de la lignée BD. Aucune différence significative d'indice métacyclique n'a été observée entre les mâles ni entre les femelles des deux lignées. Cependant, la CV des mouches de la lignée MA a été plus importante que celle des mouches de la lignée BD. Aucune différence significative de CV n'a été notée entre les mâles et les femelles de la lignée BD, tandis que chez la lignée MA, la CV des mâles a été plus importante que celle des femelles.
Interactions entre le vecteur et le trypanosome dans la détermination de la compétence vectorielle des glossines
Authors: Kazadi J.M. , Geerts S. , Kageruka P. , Losson Bertrand , Torreele G.
Published: September 2024

Cette étude a été menée pour étudier les interactions entre la glossine et le trypanosome dans la détermination de la métacyclogenèse. A cet égard, 5 257 mouches ténérales des deux sexes des lignées Glossina palpalis gambiensis (Maisons-Alfort), G. p. palpalis (Mongo-Bemba) et G. morsitans morsitans (Mall) ont été utilisées. Elles ont été nourries une fois sur rats infectés par Trypanosoma brucei gambiense (souches Mba et Phanzu), T. b. brucei (souche EATRO 1125) et T. congolense (clone IL 1180 et stock Agriumbe). La compétence vectorielle (CV) des mouches des deux lignées palpalis a été nulle ou négligeable vis-à-vis de tous les trypanosomes testés, excepté pour les clones et stock de T congolense. Celle de G. m. morsitans a été nulle pour les deux souches gambiense, mais relativement élevée (32 %) pour T. b. brucei EATRO 1125. La CV de G. m. morsitans pour T. congolense, s'est révélée plus importante pour le clone IL 1180 (95,45 %) que le stock Agriumbe (48,40 %). Ces résultats montrent une très bonne interaction entre les mouches de la lignée G. m. morsitans (Mall) et la souche clonale T. congolense IL 1180.
Un nouveau dispositif expérimental pour la mise au point de pièges à tsé-tsé. Premier essai sur Glossina fuscipe fuscipes en République centrafricaine
Authors: Gouteux J.P.
Published: September 2024

Un nouveau protocole qui présente l'intérêt d'associer dans la même expérience le carré latin et la compétition de deux pièges en vis-à-vis a été testé sur Glossina fuscipes fuscipes en République Centrafricaine.
Sifat Mekanik dan Kemampuan Biodegradasi Antimicrobial Bioplastic Berbasis Kulit Buah Naga Merah (Hylocereus polyrhizuz) dan Ekstrak Daun Biduri (Calotropis gigantea)
Authors: Arista Yuvita Lira Vesti , Mutamimah Dewi
Published: September 2024

Plastic is often chosen as packaging for food products because it’s considered practical, non-corrosive, low cost, and able to withstand product water migration, but it’s difficult to degrade. So that need biodegradable plastic untuk handle that, but most of the biodegradable plastics that have been developed only focus on ease of degradation, do not focus on the microbial contamination problem. One alternative that can be developed is to make antimicrobial bioplastic based on starch from dragon fruit peel and biduri leaves as an antimicrobial source. Until now there is no further information regarding the mechanical properties and degradation ability of antimicrobial bioplastic based on starch from dragon fruit peel and biduri leaf waste. Therefore this research was carried out to determine the mechanical properties including tensile strength, modulus young, and elongation as well as degradation ability. The research was conducted using the completely randomized design factorial method which consists of 2 factors where the first factor was variation of the dragon fruit peel starch (P1: 15%, P2: 30%, P3: 45%, P4: 60%) and the second factor was the addition of biduri leaf extract (B1: 3%, B2: 6%, B3: 9%, B4: 12%. Research on the mechanical properties of elongation, tensile strength tests, and elongation at break tests was carried out using Mat. Testing Machine while Young's modulus testing uses tension testing. Antimicrobial bioplastic degradation capability testing using Aspergillus niger is calculated based on weight loss. The research results showed that the treatment with the addition of 15% dragon fruit peel starch (P1) had good mechanical properties ranging from tensile strength, modulus young, and elongation, while the addition of biduri extract had no effect. The best biodegradation ability was with the addition of 60% starch (P4). The use of starch in greater concentrations can reduce mechanical properties but increase biodegradation capacity.
Keywords: antimicrobial packaging, biodegradable polymer, cross linkig, starch