bluuebunny/crossref_metadata_2025 huggingface dataset:
Air Pollution, Neonatal Immune Responses, and Potential Joint Effects of Maternal Depression
Authors: Hahn Jill , Gold Diane R. , Coull Brent A. , McCormick Marie C. , Finn Patricia W. , Perkins David L. , Rifas Shiman Sheryl L. , Oken Emily , Kubzansky Laura D.
Published: May 2021

Prenatal maternal exposure to air pollution may cause adverse health effects in offspring, potentially through altered immune responses. Maternal psychosocial distress can also alter immune function and may increase gestational vulnerability to air pollution exposure. We investigated whether prenatal exposure to air pollution is associated with altered immune responses in cord blood mononuclear cells (CBMCs) and potential modification by maternal depression in 463 women recruited in early pregnancy (1999–2001) into the Project Viva longitudinal cohort. We estimated black carbon (BC), fine particulate matter (PM2.5), residential proximity to major roadways, and near-residence traffic density, averaged over pregnancy. Women reported depressive symptoms in mid-pregnancy (Edinburgh Postnatal Depression Scale) and depression history by questionnaire. Immune responses were assayed by concentrations of three cytokines (IL-6, IL-10, and TNF-α), in unstimulated or stimulated (phytohemagglutinin (PHA), cockroach extract (Bla g 2), house dust mite extract (Der f 1)) CBMCs. Using multivariable linear or Tobit regression analyses, we found that CBMCs production of IL-6, TNF-a, and IL-10 were all lower in mothers exposed to higher levels of PM2.5 during pregnancy. A suggestive but not statistically significant pattern of lower cord blood cytokine concentrations from ever (versus never) depressed women exposed to PM2.5, BC, or traffic was also observed and warrants further study.
Effects of Lingual and Palatal Site Toothbrushing on Periodontal Disease in the Elderly: A Cross-Sectional Study
Authors: Yang Byung-Ik , Park Ji-A , Lee Jae-Young , Jin Bo-Hyoung
Published: May 2021

(1) Background: To analyze the association between periodontal health status and daily oral health activities including lingual and palatal site toothbrushing. (2) Methods: One hundred and fifty Korean elderly people aged >65 years participated in the study. Clinical examination regarding oral health status, including periodontal health status, was evaluated, and data on the oral health activities, socio-demographic factors, and systemic health-related factors were obtained using a questionnaire. Statistical analyses assessed the differences of periodontal health status according to daily oral health activities, including lingual and palatal site toothbrushing. (3) Results: Oral health activities including lingual and palatal site toothbrushing, frequency of toothbrushing, use of an interdental toothbrush, dietary patterns, and activity dependence correlated with bleeding on probing (BOP) and periodontitis. After adjusting for covariates, the prevalence of periodontitis was lower in the group where the inner surfaces of the teeth were partially or wholly cleaned than in the group without such cleaning. High BOP was significantly associated with the brushing of the inner surfaces of teeth. (4) Conclusions: Lingual and palatal site toothbrushing was associated with good periodontal health status in the elderly; the importance of brushing the inner surfaces of teeth should be emphasized for them and their caregivers.
Forecasting of Lung Cancer Incident Cases at the Small-Area Level in Victoria, Australia
Authors: Wah Win , Stirling Rob G. , Ahern Susannah , Earnest Arul
Published: May 2021

Predicting lung cancer cases at the small-area level is helpful to quantify the lung cancer burden for health planning purposes at the local geographic level. Using Victorian Cancer Registry (2001–2018) data, this study aims to forecast lung cancer counts at the local government area (LGA) level over the next ten years (2019–2028) in Victoria, Australia. We used the Age-Period-Cohort approach to estimate the annual age-specific incidence and utilised Bayesian spatio-temporal models that account for non-linear temporal trends and area-level risk factors. Compared to 2001, lung cancer incidence increased by 28.82% from 1353 to 1743 cases for men and 78.79% from 759 to 1357 cases for women in 2018. Lung cancer counts are expected to reach 2515 cases for men and 1909 cases for women in 2028, with a corresponding 44% and 41% increase. The majority of LGAs are projected to have an increasing trend for both men and women by 2028. Unexplained area-level spatial variation substantially reduced after adjusting for the elderly population in the model. Male and female lung cancer cases are projected to rise at the state level and in each LGA in the next ten years. Population growth and an ageing population largely contributed to this rise.
Effect of the COVID-19 Pandemic on Medical Student Career Perceptions: Perspectives from Medical Students in China
Authors: Cai Carla Zi , Lin Yulan , Alias Haridah , Hu Zhijian , Wong Li Ping
Published: May 2021

Our aim was to examine perceived occupational turnover intentions among medical students and the associated factors. A cross-sectional study using a Web-based survey was conducted. A total of 2922 completed responses were received (response rate 55.7%). A total of 58.4% (95% CI 56.6–60.2) reported high turnover intention (score of 7–15). The odds of higher total turnover score among the fifth-year students was nearly four times that of first-year students (OR = 3.88, 95% CI 2.62–5.73). Perception of the medical profession as not being of high social status and reputation significantly influenced high turnover intention scores (OR = 2.26, 95% CI 1.90–2.68). All three dimensions of the multidimensional scale of perceived social support (MSPSS) significantly predict turnover intention. Lower scores in the support from Significant Other (OR = 1.47, 95% CI 1.17–1.84), Family (OR = 1.47, 95% CI 1.18–1.83) and Friend (OR = 1.42, 95% CI 1.14–1.77) subscales were associated with higher turnover intention. Low score in the Brief Resilience Scale (BRS) was also associated with higher turnover intention (OR = 1.44, 95% CI 1.17–1.77). The findings shed light on the importance of changing public attitudes towards respecting the medical profession and improving the implementation of policies to protect the well-being of people in the medical profession.
Determination of 40 Elements in Powdered Infant Formulas and Related Risk Assessment
Authors: Astolfi Maria Luisa , Marotta Daniela , Cammalleri Vittoria , Marconi Elisabetta , Antonucci Arianna , Avino Pasquale , Canepari Silvia , Vitali Matteo , Protano Carmela
Published: May 2021

The aim of the study was to analyze all powdered infant formulas authorized and commercialized in Italy at the time of the study to measure the concentrations of 40 elements, and to estimate the infants’ intake of some toxic heavy metals for assessing possible related health risks. For this purpose, an optimized multi-element method was used through inductively coupled plasma mass spectrometry. Be, B, Al, Zr, Nb, Sb, Te, W, V, Cr and As concentrations were <LOD in more than 30% of samples. The levels of the other elements resulted to be very variable (more than 2000 µg g−1 for Ca and K or less than 1 ng g−1 for others). The results were similar to those reported by other European Union (EU) studies, but different from those recovered outside the EU. These differences should be eliminated to guarantee the right to health worldwide. The concentrations of Cd, Mn, Ni, Pb, and Zn in the infant formulas studied were always below the considered limits. However, it is important to check for potentially toxic elements in infant formulas to protect the health of this sensitive population. The data found in this study could be used as benchmark data for future research.
The Impact of Work Characteristics on Social Distancing: Implications at the Time of COVID-19
Authors: Kokubun Keisuke , Yamakawa Yoshinori
Published: May 2021

The coronavirus disease (COVID-19) continues to spread globally. While social distancing has attracted attention as a measure to prevent the spread of infection, some occupations find it difficult to implement. Therefore, this study aims to investigate the relationship between work characteristics and social distancing using data available on O*NET, an occupational information site. A total of eight factors were extracted by performing an exploratory factor analysis: work conditions, supervisory work, information processing, response to aggression, specialization, autonomy, interaction outside the organization, and interdependence. A multiple regression analysis showed that interdependence, response to aggression, and interaction outside the organization, which are categorized as ”social characteristics,” and information processing and specialization, which are categorized as “knowledge characteristics,” were associated with physical proximity. Furthermore, we added customer, which represents contact with the customer, and remote working, which represents a small amount of outdoor activity, to our multiple regression model, and confirmed that they increased the explanatory power of the model. This suggests that those who work under interdependence, face aggression, and engage in outside activities, and/or have frequent contact with customers, little interaction outside the organization, and little information processing will have the most difficulty in maintaining social distancing.
How I Feel About My School—Adaptation and Validation of an Educational Well-Being Measure among Young Children in Sweden
Authors: Riad Rasmus , Allodi Mara , Siljehag Eva , Wikman Carina , Ford Tamsin , Bölte Sven
Published: May 2021

The well-being of children has received increasing attention in recent years. Nevertheless, we lack adequate brief self-report tools that enable us to consider young children’s well-being in policy evaluations and educational research. This study describes the adaptation and first validation of the Swedish version of How I Feel About My School (HIFAMS), a subjective well-being questionnaire suitable for children aged 4 to 12 years, which was originally developed in the United Kingdom (UK). Descriptive statistics with analysis of psychometric properties and confirmatory factor analysis (CFA) are based on the perceived well-being of 228 children in preschool and school aged 5 to 8 years old. The CFA endorsed a good fit to a one-factor model, and the scale showed moderate internal consistency (rα = 0.63). The results are largely in line with the findings of the original HIFAMS. We conclude that the Swedish version can be applied in early preschool/school settings and could provide first-hand information about children’s well-being from the first years of education until elementary school grades. Practitioners in early education settings might benefit from HIFAMS assessments when seeking to understand children’s current well-being to provide support to children with special educational needs or children at risk for mental health issues. Researchers could use the HIFAMS to standardize child well-being evaluations in policy evaluations and interventional studies.
Analysis of Bio-Risk Management System Implementation in Indonesian Higher Education Laboratory
Authors: Bowolaksono Anom , Lestari Fatma , Satyawardhani Saraswati Andani , Kadir Abdul , Maharani Cynthia Febrina , Paramitasari Debby
Published: May 2021

Developing countries face various challenges in implementing bio-risk management systems in the laboratory. In addition, educational settings are considered as workplaces with biohazard risks. Every activity in a laboratory facility carries many potential hazards that can impact human health and the environment and may cause laboratory incidents, including Laboratory Acquired Infections (LAIs). In an effort to minimize the impact and occurrence of these incidents, it is necessary to evaluate the implementation of a bio-risk management system in every activity that involves handling biological agents. This study was conducted in an Indonesian higher-education institution, herein coded as University Y. This is a descriptive, semi-quantitative study aimed at analysing and evaluating the implementation of the bio-risk management systems used in laboratories by analysing the achievements obtained by each laboratory. The study used primary data that were collected using a checklist which referred to ISO 35001:2019 on Laboratory Bio-risk Management. The checklist consisted of 202 items forming seven main elements. In addition, secondary data obtained from literature and document review were also used. The results show that out of 11 laboratories examined, only 2 laboratories met 50% of the requirements, which were Laboratory A and B, achieving good performance. Regarding the clauses of standards, a gap analysis identified leadership, performance evaluation, and support as elements with the lowest achievement. Therefore, corrective action should be developed by enhancing the commitment from management as well as improving documentation, policy, education and training.
Does Risk Awareness of COVID-19 Affect Visits to National Parks? Analyzing the Tourist Decision-Making Process Using the Theory of Planned Behavior
Authors: Seong Bo-Hyun , Hong Chang-Yu
Published: May 2021

This study aimed to determine whether risk awareness of coronavirus disease (COVID-19) affects visits to national parks. We analyzed the tourist decision-making process during the current pandemic using the theory of planned behavior as a framework, adding variables relevant to the pandemic, such as risk perception and risk reduction behavior, to the model. Based on a literature review, we developed a research model describing the impact relationship between risk perception, the theory of planned behavior, and risk reduction behavior and tested nine hypotheses. Results of a survey of 555 visitors to two national parks supported eight of the nine hypotheses. Although the results are limited, they reaffirm the usefulness of the theory of planned behavior in explaining tourism behavior. This work is significant in that we would be able to extend the scope of subsequent research beyond a discussion of the direct effects on optimistic perceptions (bias) and risk reduction behavior as well as visit intention, by explaining the probability even in unprecedented crises such as COVID-19. Humans may be negotiating the constraints (COVID-19) or embodied tourism need through the personal bias. Furthermore, we discuss the theoretical implications of the results for tourism behavior research.
Patients’ Behavior Regarding Dietary or Herbal Supplements before and during COVID-19 in Saudi Arabia
Authors: Aldwihi Leen A. , Khan Shahd I. , Alamri Faisal F. , AlRuthia Yazed , Alqahtani Faleh , Fantoukh Omer I. , Assiri Ahmed , Almohammed Omar A.
Published: May 2021

The use of traditional medicinal plants in Saudi Arabia stems mainly from consumers’ belief in prophetic medicine. This study was conducted to explore changes in patients’ use of dietary or herbal supplements among individuals infected with COVID-19 before and during infection and the association between herbal or dietary supplements and hospitalization. A cross-sectional, questionnaire-based study was conducted enrolling symptomatic patients who had recently recovered from COVID-19. Data were collected through phone interviews, and McNemar’s test was used to investigate changes to consumption of dietary or herbal supplements before and during infection. Multivariable logistic regression was used to investigate the association between supplements use during patients’ infection and hospitalization. A total of 738 patients were included in this study, of whom 32.1% required hospitalization. About 57% of participants were male with a mean age of 36.5 (±11.9) years. The use of lemon/orange, honey, ginger, vitamin C, and black seed among participants significantly increased during their infection. In contrast, patients using anise, peppermint, and coffee peel before their infection were more likely to stop using them during their infection. In addition, using lemon/orange (p < 0.0001), honey (p = 0.0002), ginger (p = 0.0053), vitamin C (p = 0.0006), black seed (p < 0.0001), peppermint (p = 0.0027), costus (p = 0.0095), and turmeric (p = 0.0012) was significantly higher among nonhospitalized patients than hospitalized ones. However, in the multivariable logistic regression, only use of vitamin C (OR = 0.51; 95% CI 0.33–0.79), peppermint (OR = 0.53; 95% CI 0.31–0.90), and lemon/orange (OR = 0.54; 95% CI 0.33–0.88) was associated with significantly lower odds of hospitalization. The study reveals that patients’ consumption of dietary or herbal supplements changed in response to their COVID-19 infection, with hospitalized patients having a lower likelihood of using these supplements. Because some supplements were associated with lower odds of hospitalization, these supplements or their bioactive components should be further investigated as feasible options for COVID-19 treatment.
PM2.5 Pollution Strongly Predicted COVID-19 Incidence in Four High-Polluted Urbanized Italian Cities during the Pre-Lockdown and Lockdown Periods
Authors: Kotsiou Ourania S. , Kotsios Vaios S. , Lampropoulos Ioannis , Zidros Thomas , Zarogiannis Sotirios G. , Gourgoulianis Konstantinos I.
Published: May 2021

Background: The coronavirus disease in 2019 (COVID-19) heavily hit Italy, one of Europe’s most polluted countries. The extent to which PM pollution contributed to COVID-19 diffusion is needing further clarification. We aimed to investigate the particular matter (PM) pollution and its correlation with COVID-19 incidence across four Italian cities: Milan, Rome, Naples, and Salerno, during the pre-lockdown and lockdown periods. Methods: We performed a comparative analysis followed by correlation and regression analyses of the daily average PM10, PM2.5 concentrations, and COVID-19 incidence across four cities from 1 January 2020 to 8 April 2020, adjusting for several factors, taking a two-week time lag into account. Results: Milan had significantly higher average daily PM10 and PM2.5 levels than Rome, Naples, and Salerno. Rome, Naples, and Salerno maintained safe PM10 levels. The daily PM2.5 levels exceeded the legislative standards in all cities during the entire period. PM2.5 pollution was related to COVID-19 incidence. The PM2.5 levels and sampling rate were strong predictors of COVID-19 incidence during the pre-lockdown period. The PM2.5 levels, population’s age, and density strongly predicted COVID-19 incidence during lockdown. Conclusions: Italy serves as a noteworthy paradigm illustrating that PM2.5 pollution impacts COVID-19 spread. Even in lockdown, PM2.5 levels negatively impacted COVID-19 incidence.
The Lived Experiences of Stigmatization in the Process of HIV Status Disclosure among People Living with HIV in Taiwan
Authors: Yu Chia-Hui , Huang Chu-Yu , Ko Nai-Ying , Tung Heng-Hsin , Huang Hui-Man , Cheng Su-Fen
Published: May 2021

People living with HIV (PLWH) face social stigma which makes disclosure of HIV status difficult. The purpose of this descriptive qualitative study was to understand the lived experiences of stigmatization in the process of disease disclosure among PLWH in Taiwan. Analysis of the semi-structured interviews from 19 PLWH in Taiwan revealed two phases and six themes. Phase one “experiences before disclosure” involved three themes: “Struggles under the pressure of concealing the HIV Status”, “Torn between fear of unemployment/isolation and desire to protect closed ones”, and “Being forced to disclose the HIV status.” Phase two “experiences after disclosure” included three themes: “Receiving special considerations and requirements from school or work”, “Receiving differential treatments in life and when seeking medical care”, and “Stress relief and restart.” Healthcare professionals need to assess stigmatization in PLWH and develop individualized approaches to assist with the disease disclosure process.
A Study of Older Adults’ Mental Health across 33 Countries during the COVID-19 Pandemic
Authors: Tyler Carmen M. , McKee Grace B. , Alzueta Elisabet , Perrin Paul B. , Kingsley Kristine , Baker Fiona C. , Arango-Lasprilla Juan Carlos
Published: May 2021

Despite older adults’ extremely high vulnerability to COVID-19 complications and death, few studies have examined how personal characteristics and the COVID-19 pandemic have impacted the mental health of older adults at the global level. The purpose of this study was to examine the relationships among demographics, COVID-19 life impacts, and depression and anxiety in adults aged 60 and older from 33 countries. A sample of 823 older adults aged 60–94 and residing in 33 countries completed a 10-min online survey following recruitment from mailing lists and social media. Being separated from and having conflicts with loved ones predicted both anxiety and depression, as did residing in a country with higher income. Getting medical treatment for severe symptoms of COVID-19 and having decreased work responsibilities predicted depression, but adjustment to working from home and younger age predicted both depression and anxiety. Participants from Europe and Central Asia reported higher depression than those from all other regions and higher anxiety than those from Latin America and the Caribbean. The COVID-19 pandemic has had serious deleterious effects on the mental health of older adults worldwide. The current findings have direct implications for mental health services that may be delivered to older adults to help facilitate healthy psychological adjustment.
Ubiquinone Metabolism and Transcription HIF-1 Targets Pathway Are Toxicity Signature Pathways Present in Extracellular Vesicles of Paraquat-Exposed Human Brain Microvascular Endothelial Cells
Authors: Vujić Tatjana , Schvartz Domitille , Iliuk Anton , Sanchez Jean-Charles
Published: May 2021

Over the last decade, the knowledge in extracellular vesicles (EVs) biogenesis and modulation has increasingly grown. As their content reflects the physiological state of their donor cells, these “intercellular messengers” progressively became a potential source of biomarker reflecting the host cell state. However, little is known about EVs released from the human brain microvascular endothelial cells (HBMECs). The current study aimed to isolate and characterize EVs from HBMECs and to analyze their EVs proteome modulation after paraquat (PQ) stimulation, a widely used herbicide known for its neurotoxic effect. Size distribution, concentration and presence of well-known EV markers were assessed. Identification and quantification of PQ-exposed EV proteins was conducted by data-independent acquisition mass spectrometry (DIA-MS). Signature pathways of PQ-treated EVs were analyzed by gene ontology terms and pathway enrichment. Results highlighted that EVs exposed to PQ have modulated pathways, namely the ubiquinone metabolism and the transcription HIF-1 targets. These pathways may be potential molecular signatures of the PQ-induced toxicity carried by EVs that are reflecting their cell of origin by transporting with them irreversible functional changes.
ABA Metabolism and Homeostasis in Seed Dormancy and Germination
Authors: Sano Naoto , Marion-Poll Annie
Published: May 2021

Abscisic acid (ABA) is a key hormone that promotes dormancy during seed development on the mother plant and after seed dispersal participates in the control of dormancy release and germination in response to environmental signals. The modulation of ABA endogenous levels is largely achieved by fine-tuning, in the different seed tissues, hormone synthesis by cleavage of carotenoid precursors and inactivation by 8′-hydroxylation. In this review, we provide an overview of the current knowledge on ABA metabolism in developing and germinating seeds; notably, how environmental signals such as light, temperature and nitrate control seed dormancy through the adjustment of hormone levels. A number of regulatory factors have been recently identified which functional relationships with major transcription factors, such as ABA INSENSITIVE3 (ABI3), ABI4 and ABI5, have an essential role in the control of seed ABA levels. The increasing importance of epigenetic mechanisms in the regulation of ABA metabolism gene expression is also described. In the last section, we give an overview of natural variations of ABA metabolism genes and their effects on seed germination, which could be useful both in future studies to better understand the regulation of ABA metabolism and to identify candidates as breeding materials for improving germination properties.
Targeting of GLUT5 for Transporter-Mediated Drug-Delivery Is Contingent upon Substrate Hydrophilicity
Authors: Nahrjou Nazanin , Ghosh Avik , Tanasova Marina
Published: May 2021

Specific link between high fructose uptake and cancer development and progression highlighted fructose transporters as potential means to achieve GLUT-mediated discrimination between normal and cancer cells. The gained expression of fructose-specific transporter GLUT5 in various cancers offers a possibility for developing cancer-specific imaging and bioactive agents. Herein, we explore the feasibility of delivering a bioactive agent through cancer-relevant fructose-specific transporter GLUT5. We employed specific targeting of GLUT5 by 2,5-anhydro-D-mannitol and investigated several drug conjugates for their ability to induce cancer-specific cytotoxicity. The proof-of-concept analysis was carried out for conjugates of chlorambucil (CLB) in GLUT5-positive breast cancer cells and normal breast cells. The cytotoxicity of conjugates was assessed over 24 h and 48 h, and significant dependence between cancer-selectivity and conjugate size was observed. The differences were found to relate to the loss of GLUT5-mediated uptake upon increased conjugate size and hydrophobicity. The findings provide information on the substrate tolerance of GLUT5 and highlight the importance of maintaining appropriate hydrophilicity for GLUT-mediated delivery.
Gangliosides as Signaling Regulators in Cancer
Authors: Sasaki Norihiko , Toyoda Masashi , Ishiwata Toshiyuki
Published: May 2021

At the plasma membrane, gangliosides, a group of glycosphingolipids, are expressed along with glycosphingolipids, phospholipids, and cholesterol in so-called lipid rafts that interact with signaling receptors and related molecules. Most cancers present abnormalities in the intracellular signal transduction system involved in tumor growth, invasion, and metastasis. To date, the roles of gangliosides as regulators of signal transduction have been reported in several cancer types. Gangliosides can be expressed by the exogenous ganglioside addition, with their endogenous expression regulated at the enzymatic level by targeting specific glycosyltransferases. Accordingly, the relationship between changes in the composition of cell surface gangliosides and signal transduction has been investigated by controlling ganglioside expression. In cancer cells, several types of signaling molecules are positively or negatively regulated by ganglioside expression levels, promoting malignant properties. Moreover, antibodies against gangliosides have been shown to possess cytotoxic effects on ganglioside-expressing cancer cells. In the present review, we highlight the involvement of gangliosides in the regulation of cancer cell signaling, and we explore possible therapies targeting ganglioside-expressing cancer.
Nerve Growth Factor Peptides Bind Copper(II) with High Affinity: A Thermodynamic Approach to Unveil Overlooked Neurotrophin Roles
Authors: Magrì Antonio , La Mendola Diego , Rizzarelli Enrico
Published: May 2021

Nerve growth factor (NGF) is a protein essential to neurons survival, which interacts with its receptor as a non-covalent dimer. Peptides belonging to NGF N-terminal domain are able to mimic the activity of the whole protein. Such activity is affected by the presence of copper ions. The metal is released in the synaptic cleft where proteins, not yet identified, may bind and transfer to human copper transporter 1 (hCtr1), for copper uptake in neurons. The measurements of the stability constants of copper complexes formed by amyloid beta and hCtr1 peptide fragments suggest that beta-amyloid (Aβ) can perform this task. In this work, the stability constant values of copper complex species formed with the dimeric form of N-terminal domain, sequence 1–15 of the protein, were determined by means of potentiometric measurements. At physiological pH, NGF peptides bind one equivalent of copper ion with higher affinity of Aβ and lower than hCtr1 peptide fragments. Therefore, in the synaptic cleft, NGF may act as a potential copper chelating molecule, ionophore or chaperone for hCtr1 for metal uptake. Copper dyshomeostasis and mild acidic environment may modify the balance between metal, NGF, and Aβ, with consequences on the metal cellular uptake and therefore be among causes of the Alzheimer’s disease onset.
Urban Areas Create Refugia for Odonates in a Semi-Arid Region
Authors: Husband Danielle M. , McIntyre Nancy E.
Published: May 2021

In western Texas, most wetlands are fed from precipitation runoff, making them sensitive to drought regimes, anthropogenic land-use activities in their surrounding watersheds, and the interactive effect between these two factors. We surveyed adult odonates in 133 wetlands (49 in grassland settings, 56 in cropland, and 28 in urban areas) in western Texas from 2003–2020; 33 species were recorded. Most species were widespread generalists, but urban wetlands had the highest species richness, as well as the most unique species of any of the three wetland types. Non-metric, multidimensional scaling ordination revealed that the odonate community in urban wetlands was distinctly different in composition than the odonates in non-urban wetlands. Urban wetlands were smaller in surface area than the other wetland types, but because they were fed from more consistently available urban runoff rather than seasonal precipitation, they had longer hydroperiods, particularly during a multi-year drought when wetlands in other land-cover contexts were dry. This anthropogenically enhanced water supply was associated with higher odonate richness despite presumably impaired water quality, indicating that consistent and prolonged presence of water in this semi-arid region was more important than the presence of native land cover within which the wetland existed. Compared to wetlands in the regional grassland landscape matrix, wetlands in agricultural and urban areas differed in hydroperiod, and presumably also in water quality; these effects translated to differences in the regional odonate assemblage by surrounding land-use type, with the highest richness at urban playas. Odonates in human environments may thus benefit through the creation of a more reliably available wetland habitat in an otherwise dry region.
Insects’ Production, Consumption, Policy, and Sustainability: What Have We Learned from the Indigenous Knowledge Systems?
Authors: Selaledi Letlhogonolo , Hassan Zahra , Manyelo Tlou Grace , Mabelebele Monnye
Published: May 2021

Edible insects can be produced sustainably, with less environmental impact than other forms of livestock. Globally, over 2000 edible insect species have been reported and are regarded as a great source of nutrition, both as food and feed. Over the years, rural people have used indigenous knowledge to either store or process such insects. However, such valuable knowledge, if not properly recorded and documented, can easily be lost. Thus, there is a need to strike a balance between the use of indigenous and scientific knowledge to produce and process these delicacies. In addition, such indigenous knowledge is vital for preserving biodiversity, since insects are good indicators of climate change as it influences their development, reproduction, and survival. Therefore, successful and sustainable solutions may lie in bringing back indigenous knowledge systems.
Contributions to the Taxonomy of Arlesminthurus Bretfeld and Calvatomina Yosii (Collembola, Symphypleona, Appendiciphora), with the Description of New Species from Northeastern Brazil
Authors: Cipola Nikolas G. , Medeiros Gleyce Da S. , Oliveira Viviane A. M. De , Barbosa Luís G. De M. , Lycarião Thainá A. , Bellini Bruno C.
Published: May 2021

Arlesminthurus Bretfeld is a small genus of Neotropical Bourletiellidae, with only four described species so far. Calvatomina Yosii is a widespread taxon of Dicyrtomidae, with most species known from the tropics. Here, we describe two new species from northeastern Brazil: Arlesminthurus caatinguensis sp. nov. and Calvatomina gladiata sp. nov. We also provide a detailed chaetotaxic study for Arlesminthurus for the first time, with updated diagnoses and identification keys for the Neotropical species of both genera and notes on their morphology. Arlesminthurus caatinguensis sp. nov. resembles A. aueti Arlé in body color pattern, male head and dental chaetotaxy. The discovery of one bothriotrichum-like sens on the large abdomen of the new species needs to be investigated as a possible generic diagnostic feature, but we suggest that this structure is homologous to the S-sens seen in at least four Bourletiellinae genera, and they are likely related to each other. Calvatomina gladiata sp. nov. belongs to the rufescens-group and resembles C. rufescens Reuter and C. guyanensis Nayrolles and Betsch in some aspects of the head, dental and abdominal chaetotaxy. These descriptions represent the first record of Arlesminthurus from Caatinga and the first nominal species of Calvatomina from Brazil.
Intra-Articular Administration of Autologous Purified Adipose Tissue Associated with Arthroscopy Ameliorates Knee Osteoarthritis Symptoms
Authors: Caforio Marco , Nobile Carmelo
Published: May 2021

The aim of this study was to evaluate the safety and efficacy of the intra-articular administration of autologous purified adipose tissue to treat knee osteoarthritis (OA) following arthroscopy. Thirty patients with radiological evidence of knee OA were recruited. A small liposuction and arthroscopic lavage and debridement were performed in the same surgical time. The harvested fat was processed intraoperatively with Lipocell (Tiss’You, RSM) to purify the adipose tissue injected into the knee. Clinical evaluations were performed with VAS, Womac, and Lequesne questionnaires before treatment and after 1, 3, 6, and 12 months of follow-up. Pain, measured with VAS, significantly decreased, showing a reduction of 53% after 1 month and 83% after a year. Functional recovery, measured with Womac, showed an improvement of 47% after 1 month post-treatment and 84% after 1 year. No adverse effects have been observed. The intra-articular administration of purified adipose tissue associated with arthroscopic lavage and debridement is a safe and significantly effective strategy in improving the symptoms of knee osteoarthritis in up to 1 year of follow-up.
From the Antenna to the Display Devices: Transformation of the Colombian Radio Industry
Authors: Barrios-Rubio Andrés
Published: May 2021

Consolidation of the digital environment has become an irreversible global reality and, for the Colombian radio industry, it implies not only assuming a process of transformation in its actions, but, above all, continuous learning. Technological innovation imposes new forms of consumption whose logic corresponds to new systems for the production, distribution and commercialization of information, culture, science and entertainment. Object of study. Adaptation of the radio medium to the digital ecosystem of audiences invites us to focus the attention of researchers on the media’s use of web-radio, app–radio and social media; the relevance of sound semiotics compared to other components of the message on users’ screens; and the alterations suffered by the business model and productive routines of the radio. Methodology. This research took as its focus of study three Colombian radio stations and their informative stations—Caracol Radio, W Radio, Blu Radio, RCN Radio and La FM—through a mixed methodology. Quantitative instruments—numerical data to monitor activities on social platforms—and qualitative instruments—interpretation of messages and visual composition of the message—allow for the monitoring and analyzing of the performance of the radio medium in the digital environment, and the tactical approach of radio agents to delineate the strategies that promote the expansion, positioning and participation of radio in the Colombian media ecosystem. Results. Normalization of connectivity, ubiquity, timelessness and interactivity are, today, inherent values of the content broadcast by the radio industry, which needs to appropriate the tastes and interests of the audience through multi-device, multi-tasking and multi-user devices. Conclusion. Consumption actions of listeners: users are concentrated on the Smartphone screens, which provides a habit of listening and monitoring that forces the media to incorporate the format—and language—of video into their productive dynamics in order to attract and retain the attention of their audiences.
Preparation of Plastics- and Foaming Agent-Free and Porous Bamboo Charcoal based Composites Using Sodium Silicate as Adhesives
Authors: Chai Weisheng , Zhang Liang , Li Wenzhu , Zhang Min , Huang Jingda , Zhang Wenbiao
Published: May 2021

Plastics and foaming agents are often used to prepare large-size and low-density bamboo charcoal (BC) based composites. In this study, a plastic-free and foaming agent-free BC based composite was prepared by substituting sodium silicate (SS) for plastics. The effect of both the BC particle sizes and the usage amount of SS on the mechanical and adsorptive properties of the BC/SS composites were investigated. The experimental results show that when the BC particle size is 270 μm and the mass ratio of BC to SS is equal to 10:5, the BC/SS composite has the optimal foaming effect and best comprehensive properties. In addition, the foaming pores of the composite are caused by water vapor, which has difficulty escaping the BC because of the blockage of SS during the hot pressing process. In the BC/SS composite (10:5), the static bending intensity and the compressive strength reach respectively 6.13 MPa and 5.5 MPa, and the average pore size and porosity are 557.85 nm and 52.03%, respectively. In addition, its formaldehyde adsorptionrate reaches 21.6%. In view of good mechanical properties, formaldehyde adsorption, and environmentally friendly performance, the BC/SS composite has a great potential as a core layer of interior building materials.
A Rheological Analysis of Biomaterial Behaviour as a Tool to Detect the Dilution of Heather Honey
Authors: Přidal Antonín , Trávníček Petr , Kudělka Jan , Nedomová Šárka , Ondrušíková Sylvie , Trost Daniel , Kumbár Vojtěch
Published: May 2021

Heather honey is a valuable and rheologically special type of honey. Its above-average selling price may motivate its intentional violation with a mixture of honey from another botanical origin, the price of which is lower on the market. This work deals with the rheological properties of such devalued heather honey in order to determine the changes in the individual rheological parameters depending on the degree of dilution of the heather honey. For this purpose, a differently diluted heather honey sample series was created and the following rheological parameters were determined: hysteresis area, n-value, yield stress (τ0), parameter B (Weltman model), parameter ϕ, or parameter C (model describing the logarithmic dependence of the complex viscosity on the angular frequency). Part of the work was research into whether the set parameters can be used as comparative parameters. It was found that the hysteresis area does not appear to be a suitable relative comparison parameter due to the high variability. The parameters that appear to be suitable are the relative parameters n-value and the parameter ϕ, which showed the greatest stability. The change in the determined rheological parameters is, depending on the degree of dilution, non-linear with a step change between the samples containing 40% (w/w) and 60% (w/w) of a heather honey.
Response Surface Methods Used for Optimization of Abrasive Waterjet Machining of the Stainless Steel X2 CrNiMo 17-12-2
Authors: Deaconescu Andrea , Deaconescu Tudor
Published: May 2021

Abrasive waterjet machining (AWJM) has a particularly high potential for the machining of stainless steels. One of the main optimization objectives of the machining of X2 CrNiMo 17-12-2 stainless steel is obtaining a minimal surface roughness. This entails selecting an optimum configuration of the main influencing factors of the machining process. Optimization of the machining system was achieved by intervening on four selected input quantities (traverse speed, waterjet pressure, stand-off distance, and grit size), with three set points considered for each. The effects of modifying the set-points of each input parameter on the surface roughness were studied. By means of response surface methodology (RSM) the combination of factor set points was determined that ensures a minimum roughness of the machined surface. The main benefit of RSM is the reduced time needed for experimenting.
Hazardous Petroleum Sludge-Derived Nitrogen and Oxygen Co-Doped Carbon Material with Hierarchical Porous Structure for High-Performance All-Solid-State Supercapacitors
Authors: Li Xiaoyu , Zhang Mingyang , Tan Zhuowei , Gong Zhiqiang , Liu Peikun , Wang Zhenbo
Published: May 2021

Rational design and sustainable preparation of high-performance carbonaceous electrode materials are important to the practical application of supercapacitors. In this work, a cost-effective synthesis strategy for nitrogen and oxygen co-doped porous carbon (NOC) from petroleum sludge waste was developed. The hierarchical porous structure and ultra-high surface area (2514.7 m2 g−1) of NOC electrode materials could provide an efficient transport path and capacitance active site for electrolyte ions. The uniform co-doping of N and O heteroatoms brought enhanced wettability, electrical conductivity and probably additional pseudo-capacitance. The as-obtained NOC electrodes exhibited a high specific capacitance (441.2 F g−1 at 0.5 A g−1), outstanding rate capability, and cycling performance with inconspicuous capacitance loss after 10,000 cycles. Further, the assembled all-solid-state MnO2/NOC asymmetrical supercapacitor device (ASC) could deliver an excellent capacitance of 119.3 F g−1 at 0.2 A g−1 under a wide potential operation window of 0–1.8 V with flexible mechanical stability. This ASC device yielded a superior energy density of 53.7 W h kg−1 at a power density of 180 W kg−1 and a reasonable cycling life. Overall, this sustainable, low-cost and waste-derived porous carbon electrode material might be widely used in the field of energy storage, now and into the foreseeable future.
Clinical Outcome of Dental Implants after Maxillary Sinus Augmentation with and without Bone Grafting: A Retrospective Evaluation
Authors: Tartaglia Gianluca Martino , Poli Pier Paolo , Connelly Stephen Thaddeus , Maiorana Carlo , Farronato Davide , Taschieri Silvio
Published: May 2021

(1) Background: The purpose of the present study was to retrospectively evaluate and compare the outcome of two sinus augmentation grafting protocols using a xenograft or blood clot alone over a 72-month follow-up. (2) Methods: Patients who received simultaneous lateral sinus floor augmentation and implant placement were included. Subjects were divided into two groups according to the grafting material, namely xenograft or blood clot, and into sub-groups based on the residual alveolar bone height (RABH) below the maxillary sinus, namely 4 to 6 mm or >6 mm. Kaplan–Meier survival estimates were calculated for each material group and for each sub-group at 1, 3, and 6 years. (3) Results: In total, 289 implants inserted in 136 patients with a one-stage procedure were considered. A total of 35 failures were registered. Overall survival rates were 94.2% for xenograft and 85.9% for blood clot alone at 1 year, 91.1% and 81.6% at 3 years, and 91.1% and 78.7% at 6 years. (4) Conclusions: In patients with 4–6 mm RABH, graftless interventions exploiting blood clot alone were not as successful as those using xenograft. When the RABH is low, sinus floor augmentation associated with grafting materials should be preferred whenever possible.
Interfacial Chemical Effects of Amorphous Zinc Oxide/Graphene
Authors: Zhao Zhuo , Fang Fang , Wu Junsheng , Tong Xinru , Zhou Yanwen , Lv Zhe , Wang Jian , Sawtell David
Published: May 2021

Research on the preparation and performance of graphene composite materials has become a hotspot due to the excellent electrical and mechanical properties of graphene. Among such composite materials, zinc oxide/graphene (ZnO/graphene) composite films are an active research topic. Therefore, in this study, we used the vacuum thermal evaporation technique at different evaporation voltages to fabricate an amorphous ZnO/graphene composite film on a flexible polyethylene terephthalate (PET). The amorphous ZnO/graphene composite film inherited the great transparency of the graphene within the visible spectrum. Moreover, its electrical properties were better than those of pure ZnO but less than those of graphene, which is not consistent with the original theoretical research (wherein the performance of the composite films was better than that of ZnO film and slightly lower than that of graphene). For example, the bulk free charge carrier concentrations of the composite films (0.13, 1.36, and 0.47 × 1018 cm−3 corresponding to composite films with thicknesses of 40, 75, and 160 nm) were remarkably lower than that of the bare graphene (964 × 1018 cm−3) and better than that of the ZnO (0.10 × 1018 cm−3). The underlying mechanism for the abnormal electrical performance was further demonstrated by X-ray photoelectron spectroscopy (XPS) detection and first-principles calculations. The analysis found that chemical bonds were formed between the oxide (O) of amorphous ZnO and the carbon (C) of graphene and that the transfer of the π electrons was restricted by C=O and C-O-C bonds. Given the above, this study further clarifies the mechanism affecting the photoelectric properties of amorphous composite films.
In Vitro Evaluation of Structural Factors Favouring Bacterial Adhesion on Orthodontic Adhesive Resins
Authors: Condò Roberta , Mampieri Gianluca , Pasquantonio Guido , Giancotti Aldo , Pirelli Paola , Cataldi Maria Elena , La Rocca Serena , Leggeri Andrea , Notargiacomo Andrea , Maiolo Luca , De Filippis Patrizia , Cerroni Loredana
Published: May 2021

Bacterial adhesion to the surface of orthodontic materials is an important step in the formation and proliferation of plaque bacteria, which is responsible for enamel demineralization and periodontium pathologies. With the intent of investigating if adhesive resins used for bracket bonding are prone to bacteria colonization, the surface roughness of these materials has been analyzed, combining information with a novel methodology to observe the internal structures of orthodontic composites. Scanning electron microscopy, combined with focus ion bean micromachining and stylus profilometry analyses, were performed to evaluate the compositional factors that can influence specific pivotal properties facilitating the adhesion of bacteria to the surface, such as surface roughness and robustness of three orthodontic adhesive composite resins. To confirm these findings, contact angle measurements and bacteria incubation on resin slide have been performed, evaluating similarities and differences in the final achievement. In particular, the morphological features that determine an increase in the resins surface wettability and influence the bacterial adhesion are the subject of speculation. Finally, the focused ion beam technique has been proposed as a valuable tool to combine information coming from surface roughness with specific the internal structures of the polymers.