bluuebunny/crossref_metadata_2025 huggingface dataset:
Measurement of Calcaneal Angles and Its Clinical Significance in Han Chinese Adults in Northwest China
Authors: Dong Xianghui , Jin ZhanKui , Sun ZhengMing , Chen Jing , Chang YanHai , Ling Ming
Published: July 2021

Objective

We aimed to investigate differences in and trends of normal calcaneal angles among Han Chinese adults from different age groups to establish normal reference ranges of calcaneal angles in these age groups, thereby providing a theoretical basis and morphological reference for the treatment of calcaneal fractures.
Methods

We collected lateral plain radiographs (X-ray) of the normal ankle joints of 6,260 Han Chinese adults who visited the Radiology Department of Shaanxi Provincial People’s Hospital between November 2008 and December 2020 to measure the calcaneal angles, including the Böhler angle (BA), Gissane angle (GA), calcaneal pitch angle (CPA), posterior facet inclination angle (PFIA), and calcaneal-tibial angle (CTA). On this basis, we analyzed the calcaneal angles in different age groups to summarize the characteristics of normal calcaneal angles in Han Chinese adults.
Results

According to the lateral plain radiographs of the normal ankle joints of 6,260 (male: 3,380; female: 2,880) adults (mean age: 46.3 ± 18.2 ), the mean values of the BA, GA, CPA, PFIA, and CTA were 33.17° ± 6.08°, 114.99° ± 8.17°, 25.67° ± 4.72°, 64.35° ± 8.51°, and 91.59° ± 11.57°, respectively. Results of the Pearson correlation analysis suggested negative correlations between age and both BA and PFIA (P < 0.01, respectively) but a lack of correlation between age and the GA, CPA or CTA (P > 0.05, respectively). One-way analysis of variance (ANOVA) and the least significant difference (LSD) test showed that at above the age of 18, there were statistically significant differences both in the BA between different age groups and in the PFIA between different age groups above 41 years old.
Conclusion

In Han Chinese adults, there are significant differences in BA and PFIA between different age groups, with these calcaneal angles exhibiting a trend of decrease with age.
A Novel Error Compensation Method of Five-axis Flank Milling of Ruled Surface by Modifying Tool Path
Authors: He Gaiyun , Yao Chenglin , Sang Yicun , Yan Yichen
Published: July 2021

Five-axis flank milling is widely used in the aerospace and automotive industry. However, diverse sources of errors prevent the improvement of machining accuracy. This paper proposes a novel error compensation method for five-axis flank milling of ruled surface by modifying the original tool path according to the error distribution model. The method contains three steps: First, the errors at the middle of the straight generatrix on the machined surface are calculated according to error distribution, and the corresponding normal vectors are obtained by geometric calculation. Second, multi-peaks Gaussian fitting method is utilized to make connections between parameters in the original tool path and error distribution. Finally, the new tool path is generated by adjusting original tool path. Machining experiments are performed to test the effectiveness of the proposed error compensation method. The error distribution after compensation shows that the average error decreases 74%, and the maximum error (contains overcutting and undercutting) decreases 26%. Results show that the proposed error compensation method is effective to improve the accuracy for five-axis flank milling.
Analysis of Vibration Reduction Mechanism for Variable-pitch End Mills in Hardened Steel
Authors: Nie Wanying , Zheng Minli , Yu Haibin , Xu Shicheng , Liu Yuexiu
Published: July 2021

The development of the machining technology is restricted by the problems of serious vibration and low system stability. The variable-pitch mill has certain vibration reduction property due to the unequal pitch angles. In this work, firstly, according to the features of the structure of the variable-pitch end mill, the cutting mechanism is analyzed, and a theoretical model of the dynamic cutting force is developed. Secondly, the cutting force coefficients of the model are determined based on the test of hardened steel for verifying the significance of the theoretical model. Then, the time-frequency characteristics and vibration reduction mechanism of variable-pitch mills are analyzed. The frequency characteristics of different types of pitch angle mills are also explored by the spectrum analysis. Finally, based on the energy and variance methods of the amplitude, the multi-objective optimization of the pitch angle is carried out, where the spectrum lines are found evenly distributed, and the optimal result is 80°-97°-100°-83°. For satisfying the machining requirements, the pitch angle of the variable-pitch end mill is reasonably selected to reduce the amplitude of the forced vibration, which can play an important role in reducing the vibration of the tool and improving its cutting stability.
Serosurvey of hepatitis A virus and E virus infection among municipal sweepers working in the largest city in the south of Iran
Authors: Sarvari Jamal , Hosseini Seyed Younes , Joharinia Negar , Hosseini Seyed Ali , Ghahestani Saeed Firoozi , Ghojoghi Rozita , Dorost Kourosh , Moghadami Mohsen , Gheshlaghi Abolfazl , Jaberi Omid , Khoshbakht Rohollah
Published: July 2021

Background

Given the importance of Hepatitis A (HAV) and Hepatitis E (HEV) infection in careers like street sweeping, this study was conducted to determine the exposure rate in urban solid waste collectors/sweepers in the south of Iran.
Materials and methods

In this cross-sectional study, the sera samples of 385 waste collectors/sweepers from all districts of Shiraz, southern Iran, were collected. A questionnaire was used to gather data on their demographic and occupational characteristics, as well as their awareness of viral hepatitis disease. The rate of HAV and HEV sero-prevalence was determined by commercial ELISA kits.
Results

All partisans were male with a mean age of 41 ± 8 years. ELISA assay showed that all of participants were positive for anti-HAV Ab. Moreover, 62out of 385 (16.1%) subjects were positive for anti-HEV IgG Ab. Also, statistical analysis showed that the frequency of IgG Ab against HEV among the age group of 20–30, 31–40, 41–50 and over 50 years old was 4.5%, 10.1%, 17.4%, and 36.7% that was statistically significant (P < 0.001). Based on the work experience, current and previous jobs, residency, personal hygiene and knowledge status of hepatitis disease and transmission, the results showed that there was no statistically significant difference between anti-HEV positive and negative sweepers (p˃0.05).
Conclusion

Our results indicated that the frequency of anti-HAV and HEV IgG among sweepers is slightly higher than the normal population; it does not seem that garbage collecting/sweeping career could be a significant risk factor for HAV and HEV infection.
Blockchain Based Intelligent Incentive Enabled Information Sharing Scheme in Future Generation IoV Networks
Authors: Alam Intyaz , Kumar Sushil , Kumar Manoj , Kashyap Pankaj Kumar
Published: July 2021

With the advancement of vehicle’s traffic information processing and communication capability in Internet of Vehicle (IoV) network widely used for the vehicle-to- infrastructure transportation communication. Firstly, the protection of the user’s (vehicles) privacy at the time of information sharing and secondly, users lack the motivation to share the traffic information with roadside units (RSUs) are two major concerns in the IoV networks. In this regard, we propose a novel adaptive neuro-fuzzy based payment using blockchain (ANFPB) transportation communication scheme that not only motivates users to take participate in the information sharing problems with the payment mechanism but also allows users to anonymously share the traffic information with RSU in the IoV network. Meanwhile, a smart contract is presented to generate pseudonyms to share the traffic information anonymously in a non-trustful IoV network. Also, an algorithm ANFPB is presented for the evaluation of payment based on location, timeline, and quality of information shared by the vehicles. Finally, the extensive simulation analysis shows that the proposed ANFPB is more efficient in terms of preserving privacy and computational costs as compared to state-of-the-art schemes.
Tauber antegrade sclerotherapy: the importance of phlebography in choosing the correct vein.
Authors: Guida Edoardo , Boscarelli Alessandro , Duci Miriam , Ceschiutti Giulia , Schleef Jurgen
Published: July 2021

Tauber antegrade sclerotherapy can be considered an established procedure for the treatment of varicocele in pediatric age. Herein, we share our experience with this technique and its tricks. The choice of the spermatic vein should be very accurate during the Tauber procedure, and a correct intraoperative phlebography is mandatory to avoid complications.
Unrestricted Social Interaction: Underappreciated Cause of COVID 19 Surge
Authors: Patel Jayendrakumar , Parikh Shalin , Patel Rakesh , Patel Shwetaben , Patel Ronak , Patel Payalben , Patel Ankita
Published: July 2021

India had the worst conditions during the second wave, and yet, its cause for the enormous spike of COVID-19 cases in short time span remains unexplained. We retrospectively studied the comparative secondary attack rate, incidence proportion rate and extent of unrestricted social interactions’ contribution between the first and second wave of COVID-19 to decipher what caused the second wave's enormous spike in COVID-19 cases. We found that the unrestricted social interaction accounted equally, i.e., >42% of all COVID-19 cases in the both waves. Overall secondary attack rate rose 58% in the second wave's, among which, we find increment of 2.5-fold and 88% for the age group <10 years and >50years, respectively, while it remains stable in the age group 10-50years. We find significantly higher incidence proportion rate, ~39%, in household size of two- and three members in the second wave while it was significant in household size of four or more members in the first wave. We anticipated that changes in the pattern of unrestricted social interaction amongst household members escalated the secondary attack rate and higher incidence proportion rate even in two members family size could lead to the unprecedented surge of COVID-19 cases in the second wave.
Novel Universal Phenomena of Single Slit, Double Slit, Cross-double Slit and Triple Slit Experiments --- Curved Patterns and Orientation-Dependence of Patterns
Authors: peng hui
Published: July 2021

Young’s double slit experiments express the mystery of quantum mechanics. To explore the mystery, varieties of the double slit and cross-double slit experiments were performed. In this article, we show novel universal phenomena: (1) the fringes of the interference patterns of the double slit/cross-double slit/triple slit experiments can be distributed along curves, and the curvatures depend on the orientations of the diaphragms; (2) the characteristics of the interference patterns of the double slit/cross-double slit/triple slit experiments depend on the orientation of the diaphragm, specifically, on which axis the diaphragm rotates around, the rotating angle and how to rotate, clockwise or counterclockwise; and (3) in the cross-double slit experiments, the interference patterns created by the tilt double slits tend to incline towards the axis that is perpendicular to the axis the diaphragm rotates around. The single slit experiments have the same phenomena that, due to the rotation of the diaphragm around different axis, either the patterns are curved or the patterns expanded. We show the novel universal phenomena of the single slit/double slit/cross-double slit/triple slit experiments, which may be utilized in the applications of, for example, the double slit.
Development of Novel Coconut Ssr Markers Derived From Genome-Wide Bioinformatics Prediction
Authors: Caro Reina Esther S. , Cagayan Jesmar , Gardoce Roanne R. , Manohar Anand Noel C. , Canama-Salinas Alma O. , Rivera Ramon L. , Lantican Darlon V. , Galvez Hayde F. , Reaño Consorcia E.
Published: July 2021

In the past, simple sequence repeat (SSR) marker development in coconut is achieved through microsatellite probing in bacterial artificial chromosome (BAC) clones or using previously developed SSR markers from closely related genomes. These coconut SSR markers are publicly available in published literatures and online databases; however, the number is quite limited. Here, we used a locally established, coconut genome-wide SSR prediction bioinformatics pipeline to generate a vast amount of coconut SSR markers. A total of 7,139 novel SSR markers were derived from the genome assembly of coconut ‘Catigan Green Dwarf’ (CATD). A subset of the markers, amounting to 131, were selected for synthesis based on motif filtering, contig distribution, product size exclusion, and success of in silico PCR in the CATD genome assembly. OligoAnalyzer-tool was also employed using the following desired parameters: %GC: 40–60%; minimum ΔG value for hairpin loop: -0.3 kcal/mol; minimum ΔG value for self-dimer: -0.9 kcal/mol; and minimum ΔG value for hetero-dimer: -0.9 kcal/mol. We have successfully synthesized, optimized, and amplified 131 novel SSR markers in coconut using ‘Catigan Green Dwarf’ (CATD), ‘Laguna Tall’ (LAGT), ‘West African Tall’ (WAT), and SYNVAR (LAGT x WAT) genotypes. Of the 131 SSR markers, 113 were polymorphic among the analyzed coconut genotypes. The development of novel SSR markers for coconut will serve as a valuable resource for mapping of quantitative trait loci (QTLs), assessment of genetic diversity and population structure, hybridity testing, and other marker-assisted plant breeding applications.
Refractory vaccine-induced thrombotic thrombocytopenia (VITT) managed with delayed therapeutic plasma exchange (TPE)
Authors: Major Ajay , Carll Timothy , Chan Clarence W. , Christenson Chancey , Wool Geoffrey D. , Cohen Kenneth S.
Published: July 2021

Vaccine-induced thrombotic thrombocytopenia (VITT) is a newly-described hematologic disorder which presents as acute thrombocytopenia and thrombosis after administration of adenovirus-based vaccines against COVID-19. Due to positive assays for antibodies against platelet factor 4 (PF4), VITT is managed similarly to autoimmune heparin-induced thrombocytopenia (HIT) with intravenous immunoglobulin (IVIG) and non-heparinoid anticoagulation. We describe a case of VITT in a 50-year-old man with antecedent alcoholic cirrhosis who presented with platelets of 7 × 103/µL and portal vein thrombosis 21 days following administration of the Ad26.COV2.S COVID-19 vaccine. The patient developed progressive thrombosis and persistent severe thrombocytopenia despite IVIG, rituximab and high-dose steroids and had persistent anti-PF4 antibodies over 30 days after his initial presentation. As such, delayed therapeutic plasma exchange (TPE) was pursued as salvage therapy, with a rapid and sustained improvement in his platelet count. Our case serves as proof-of-concept of the efficacy of TPE in VITT.
Evaluation of Groundwater quality and suitability for irrigation using hydro-chemical process in Bhavani taluk, Erode District, Tamilnadu, India
Authors: Bari Jabar Abdul , Perumal Karthikeyan , Muthuramalingam Subagunasekar
Published: July 2021

In most regions of the present study area, Bhavani Taluk, groundwater quality is deteriorating at an alarming rate as a result of anthropogenic activities, however, little attention was given to groundwater quality and management. This research examines the quality of groundwater in Bhavani Taluk, Tamilnadu and compares its suitability for irrigation. The Bhavani region of Erode District, Tamilnadu is the most cultivated, with a considerable use of fertilizers and pesticides. Groundwater quality for irrigation purposes was assessed during the pre-monsoon season by collecting samples from 53 different locations. Physico-chemical parameters such as pH, EC, TDS, HCO3−, CO32−, Cl−, SO42−, NO3−, Ca2+, Mg2+, Na+ and K+were measured in these groundwater samples. Irrigation quality measures such as salinity hazard, sodium hazard expressed as SAR, percentage of sodium (% Na), and permeability index (PI) were calculated to evaluate groundwater quality for agricultural irrigation. Based on the classification of Electrical conductivity (EC) most of the groundwater samples are falling under the permissible limit. As per the USSL diagram, the large majority of groundwater samples fall within the category of C3-S1 and the water is suitable for irrigation. Piper trilinear diagram interpretations were made to know the chemical type of the groundwaters. The piper diagram indicates that 50% of the groundwater sample were belongs to Mg2+, Ca2+, HCO3−, and Cl−. The groundwater samples fall under Class I category according to Doneen’s Classifications.
Petrographic structures: Khibiny ijolites and urtites
Authors: Voytekhovsky Yuri Leonidovich , Zakharova Alena Alexandrovna
Published: July 2021

In addition to the standard description of the structures and textures of crystalline rocks the mathematical approaches have been proposed based on a rigorous determination of the petrographic structure through the probabilities of binary intergrain contacts. In general, the petrographic structure is defined as an invariant aspect of rock organization, algebraically expressed by the canonical diagonal form of the symmetric Pij matrix and geometrically visualized by structural indicatrices - surfaces of the 2nd order. The agreed nomenclature of possible petrographic structures for an n-mineral rock is simple: the symbol Snm means that there are exactly m positive numbers in the canonical diagonal form of the Pij matrix. New types of barycentric diagrams have been proposed. To describe the massive texture, the concept of Hardy - Weinberg equilibrium has been proposed. This boundary classifies barycentric diagrams into areas within which canonical types of Рij matrices and topological types of structural indicatrices are preserved. The change in the organization of the rock within a type is quantitative, the transition from one type to another means structural restructuring. The methods are used to describe ijolites and urtites of the Khibiny massif, the Kola Peninsula. In the modern taxonomy of rocks, the boundaries between them are mostly conditional and are drawn according to the contents of rock-forming minerals, for example, between ijolites and urtites - according to the contents of nepheline and pyroxene. The strict definition of the petrographic structure proposed by the authors makes it possible to introduce into petrography the constitutional principle (structure + composition), which is successfully acting in mineralogy.
Drought tolerance of hybrid tea rose varieties in the conditions of the Right-Bank Forest-Steppe of Ukraine
Authors: Vaskivska Svitlana
Published: July 2021

Purpose. To reveal drought resistance of hybrid tea rose varieties of garden group in field and laboratory conditions.
Methods. Field, biometric, laboratory, statistical. The drought resistance of plants in the field was assessed according to S. S. Pyatnitsky 6-point scale (1961); experiments in the laboratory were to determine the water hol­ding capacity of leaves, their water deficiency, the ability to restore turgor, hydration of tissues according to the unified method of the Institute of Horticulture NAAS (Kytaiev et al., 1998, 2009).
Results. According to visual observations in periods with low moisture supply, leaf turgor did not decrease, so in the field, drought resistance of hybrid tea roses was estimated at 5 points on a 6-point scale. In the laboratory, water deficiency in the leaves was calculated (as a percentage of the total water content in the state of full saturation). According to the indicators of the water-holding capacity of leaf tissues, varieties with the level of moisture loss in the exposure after 12 hours from the lowest to the highest, were selected.
Conclusions. All varieties of hybrid tea roses from the collection of M. M. Gryshko NBG of NAS of Ukraine, included in the experiment, in field conditions were rather drought-resistant. According to the indicators of drought resistance of leaves from 44 model varieties, 9 with low (up to 22.30%), 5 with medium (up to 24.37%), 30 with high and very high level of moisture loss were identified (27.23–46.47%). Analysis of the research results shows that the physiological processes associated with water loss are a variety-specific, genetically inherited trait. Varieties of hybrid tea roses of diffe­rent geographical origin, which showed the criterion of drought resistance from medium to highest, can be recommended for cultivation in the Right-Bank Forest-Steppe of Ukraine.
Effects of catnip (Nepeta cataria L.) and Mexican sunflower (Tithonia diversifolia L.) density on growth, yield, and proximate composition of jute mallow (Corchorus olitorius L.)
Authors: Ayodele O. P. , Aluko O. A. , Adegbaju O. D.
Published: July 2021

Purpose. Jute mallow (Corchorus olitorius L.) is a mucilaginous vegetable and fiber crop cultivated in the tropics, where catnip (Nepeta cataria L.) and Mexican sunflower (Tithonia diversifolia L.) are common weeds. Hence, the study investigated the growth, yield, and nutrient level of jute mallow in weed-free, catnip, and Mexican sunflower environments.
Methods. The study involved two screen-house experiments in a Completely Randomized Design (CRD) with six replications. The treatments were 0 (control), 2, 4, 6, 8, and 10 weed plants per pot in both experiments. These are 0, 100, 200, 300, 400, and 500 weed count per square meter equivalent, based on the surface area of the pots used. Mexican sunflower and catnip plants interacted with jute plants in the first and second experiments, respectively. Growth parameters of jute mallow were recorded weekly from 5 to 8 weeks after sowing (WAS), and harvesting was done at 8 WAS. The proximate composition of jute was evaluated using standard procedures outlined by AOAC. The data collected were subjected to analysis of variance (ANOVA), and means were separated using Duncan Multiple Range Test (DMRT) at P < 0.05.
Results. Catnip and Mexican sunflower negatively impacted the morphological features of jute mallow from 100 plants per square meter upwards. Catnip and Mexican sunflower, at 300 and 100–500 plants per square meter, respectively, reduced the dry weight of jute mallow. The crude protein content of jute mallow was also lessened by Mexican sunflower at some point.
Conclusions. The study recommends that the density of catnip and Mexican sunflower plants interacting with jute mallow should be maintained below 100 plants per square meter to prevent yield loss.
Fuzzy linear regression analysis for groundwater response to meteorological drought in the aquifer system of Xanthi plain, NE Greece
Authors: Papadopoulos Christopher , Spiliotis Mike , Gkiougkis Ioannis , Pliakas Fotios , Papadopoulos Basil
Published: July 2021

This paper studies, through the principles of fuzzy set theory, groundwater response to meteorological drought in the case of an aquifer system located in the plains at the southeast of Xanthi, NE Greece. Meteorological drought is expressed through standardized Reconnaissance Drought Index (RDISt) and Standardized Precipitation Index (SPI), which are calculated for various reference periods. These drought indices are considered as independent variables in multiple fuzzy linear regression based on Tanaka's model, while the observed water table regarding two areas is used as a dependent variable. The fuzzy linear regression of Tanaka is characterized by the inclusion constraints where all the observed data must be included in the produced fuzzy band. Hence, each fuzzy output can get an interval of values where a membership degree corresponds to each of them. A modification of the Tanaka model by adding constraints is proposed in order to avoid irrational behavior. The results show that there was a significant influence of the meteorological drought of the previous hydrological year, while geology plays an important role. Furthermore, the use of RDISt improves the results of fuzzy linear regressions in all cases. Two suitability measures and a measure of comparison between fuzzy numbers are used.
Hourly water demand forecasting using a hybrid model based on mind evolutionary algorithm
Authors: Huang Haidong , Zhang Zhixiong , Lin Zhenliang , Liu Shitong
Published: July 2021

A hybrid model based on the mind evolutionary algorithm is proposed to predict hourly water demand. In the hybrid model, hourly water demand data are first reconstructed to generate appropriate samples so as to represent the characteristics of time series effectively. Then, the mind evolutionary algorithm is integrated into a back propagation neural network (BPNN) to improve prediction performance. To investigate the application potential of the proposed model in hourly water demand forecasting, real hourly water demand data were applied to evaluate its prediction performance. In addition, the performance of the proposed model was compared with a traditional BPNN model and another hybrid model where the genetic algorithm (GA) is used as an optimization algorithm for BPNN. The results show that the proposed model has a satisfactory prediction performance in hourly water demand forecasting. On the whole, the proposed model outperforms all other models involved in the comparisons in both prediction accuracy and stability. These findings suggest that the proposed model can be a novel and effective tool for hourly water demand forecasting.
Colorectal Serrated Lesions: A Current View on Clinical, Morphological,
Molecular, and Genetic Diagnostic Criteria
Authors: Mikhaleva Liudmila M. , Vandysheva Rositsa A. , Midiber Konstantin Yu. , Vasyukova Olesya A. , Pechnikova Valentina V. , Patsap Olga I. , Beylerli Ozal , Somasundaram Siva G. , Kirkland Cecil E. , Aliev Gjumrakch
Published: July 2021

Objective:

Serrated colorectal lesions are a group of colonic lesions with a serrated
(saw-tooth) profile of the surface epithelium and crypts, and peculiar molecular and
genetic developmental mechanisms that are incompletely understood. These formations
cause concern due to their premalignant potential.

Aim:

The review is dedicated to serrated lesions of colon and appendix. We focused on
modern classification, role in carcinogenesis, as well as new approaches to morphological
diagnosis.

Methods:

A literature search was performed using PubMed, Scopus, ResearchGate, Google,
MEDLINE, and ScienceDirect databases to find studies of serrated colorectal lesions
related cancer published between 2000 and 2020 that address epidemiological risk factors,
underlying pathophysiological mechanism and enable our review of these factors as
well as molecular, genetics, and structural patterns.

Results:

Serrated colorectal lesions take one third of all benign neoplasms of the colon in
the pathologist’s practice. The active study of serrated lesions began in the 1900s. Terminology
and diagnostic criteria changed in the updated classification in 2019. Morphological
criteria, immunohistochemical and molecular profile, endoscopic and clinical characteristics
are reviewed.

Conclusion:

Although significant efforts were made in attempt to improve our understanding
and diagnostic criteria of serrated polyps of colorectum, very little has changed
since the original morphologic description of preneoplastic serrated lesions in early
2000s. There remains a need for more research in order to develop more definitive immuophenotypic
and molecular biomarkers in order to distinguish between non-neoplastic
and neoplastic serrated lesions.
Oxidative Stress and Cellular Senescence: The Key Tumor-promoting Factors in Colon Cancer and Beneficial Effects of Polyphenols in Colon Cancer Prevention
Authors: Bhatiya Meenu , Pathak Surajit , Banerjee Antara
Published: July 2021

Background:

Colon cancer is the third leading cause of cancer-related deaths worldwide. Colon tumorigenesis is a sequential process called “Adenoma-carcinoma sequence”. The alimentary habits, obesity, heavy alcohol consumption, inflammatory bowel diseases, family history of colon cancer, oxidative stress, and cellular senescence are the major risk factor influencing colon cancer development. Senescence contributes to the aging process as well as the development and progression of colon cancer. However, the precise mechanism underlying the aging-related progress of colon cancer is yet to be answered. Recent studies proposed that the senescent cell secretes Senescence-Associated Secretory Phenotype (SASP) includes pro-inflammatory cytokines, interleukins, growth factors, and proteases actively involved in the creation of pro-tumorigenic microenvironment.

Objective:

This review aims to provide an overview of ROS influence cellular senescence and colon cancer development as well as summarize the antioxidant and antiaging activity of natural flavonoids. Many of the studies had reported that pro-aging genes suppress cancer and various ‘markers’ are used to identify senescent cells in vitro and in vivo. The SASP of the cells may act as a link between senescence and cancer.

Conclusion:

This review facilitates a better understanding and might contribute to diagnostic and prognostic systems as well as to find out the novel and targeted therapeutic approaches. Additionally, we focused on the potential role of natural flavonoids in colon cancer therapies and highlighting the flavonoid-based treatments as innovative immunomodulatory strategies to inhibit the growth of colon cancer.
The Use of Nanoparticles to Enhance Performance in the Textile Industry -
A Concise Review
Authors: Perera Shamara , Wijesekara Dilendra , Thiripuranathar Gobika , Menaa Farid
Published: July 2021

:

Nanotechnology in the textile industry has gained popularity in the commercial market
over the years. It is based on utilizing the characteristic properties of nanomaterials to improve the
functionality of the textile. The present article focuses on different types of nano moieties, their
properties, such as water repellence, self-cleaning, UV-protection, anti-microbial and flame retardancy,
and their applications in various sectors. We also discuss smart textiles, operating mechanisms,
and their economic importance. We conclude that the successful application of nanotechnology in
the textile industry lies in producing sustainable and multifunctional fabrics to meet the increasing
customer demand.
Comparison of Methods for Detecting Methicillin-Resistant Coagulase-Negative Staphylococci in Device-Associated Infections
Authors: Amer Wesam Hatem , Abd Elghafar Mohamed Samir , Abd-El-monsef Marwa Mohamed Ezzat
Published: July 2021

Background:

Coagulase-negative Staphylococci (CoNS) is one of the major causes of infections
in hospitals. Methicillin resistance has greatly increased in different CoNS species in previous
years. Here, we evaluated the performance of four phenotypic tests for detecting mecA-mediated
methicillin resistance rate in CoNS isolated from different device-associated infections in Tanta
University Hospitals, Egypt.

Methodology:

One hundred and fifteen CoNS isolates were examined for mecA-mediated methicillin
resistance using polymerase chain reaction (PCR) as the standard gold test. Susceptibility to
methicillin was investigated using VITEK 2 assay, oxacillin broth microdilution, and cefoxitin disc
diffusion tests.

Results:

Of all isolates, 98.3% were mecA-positive. The sensitivities of the different methods examined
were as follows: 100% for the VITEK cefoxitin test, 97.4% for the VITEK oxacillin test,
93.8% for the oxacillin broth microdilution, and 82.3% for the cefoxitin disc diffusion test. The test
specificity could not be accurately determined because of the small number of mecA-negative isolates
(n = 2).

Conclusion:

The rate of methicillin resistance reached 98.3% among CoNS isolates. Our results demonstrate
that the VITEK 2 assay is rapid and has high sensitivity compared to other phenotypic
methods for detecting methicillin resistance among different species of CoNS. Therefore, we recommend
the dual measurement of both cefoxitin and oxacillin susceptibilities using the VITEK 2
assay for best results.
Withdrawal Notice: Detection of Electricity Theft by Applying Deep Learning Techniques in Electrical Distribution Network: A Comprehensive Review
Authors: Yadav Rakhi , Kumar Yogendra
Published: July 2021

The article has been withdrawn at the request of the editor of the journal Recent Advances in Computer Science and
Communications due to incoherent content.

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Data Analytics and Modeling in IoT-Fog Environment for Resourceconstrained
IoT-Applications: A Review
Authors: Farooq Omar , Singh Parminder
Published: July 2021

Introduction:

The emergence of the concepts like Big Data, Data Science, Machine
Learning (ML), and the Internet of Things (IoT) in recent years has added the potential of research
in today's world. The continuous use of IoT devices, sensors, etc. that collect data continuously is
putting tremendous pressure on the existing IoT network.

Materials and Methods:

This resource-constrained IoT environment is flooded with data acquired
from millions of IoT nodes deployed at the device level. The limited resources of the IoT Network
have driven the researchers towards data Management. This paper focuses on data classification at
the device level, edge/fog level, and cloud level using machine learning techniques.

Results:

The data coming from different devices is vast and is of variety. Therefore, it becomes
essential to choose the right approach for classification and analysis. This will help in optimizing
the data at the device, edge/fog level for better performance of the network in the future.

Conclusion:

This paper presents data classification, machine learning approaches, and a proposed
mathematical model for the IoT environment.
Revistas Científicas de Comunicação Ibero-Americanas na Política de Divulgação do Conhecimento: Tendências, Limitações e os Desafios de Novas Estratégias
Authors: Peruzzo Cicilia M. Krohling , Martins Moisés de Lemos , Gabrioti Rodrigo
Published: July 2021

Esta edição resulta dos debates, troca de ideias e investigações sobre as condições e políticas de difusão da produção científica em Comunicação e dos temas que lhes estão associados, tais como, os critérios para indexação de revistas, os sistemas de métricas de avaliação de impacto, os critérios e as hierarquias na circulação do conhecimento produzido, a importância do acesso aberto e a divulgação do conhecimento nos diferentes idiomas – Português, Espanhol e Inglês –, no espaço ibero-americano. Debates, durante mais de seis anos, proporcionados pelo Fórum de Publicações e Difusão de Conhecimento Científico da Confederação Ibero-Americana das Associações Científicas e Acadêmicas de Comunicação (Confibercom). Intitulada Revistas Científicas de Comunicação Ibero-Americanas na Política de Divulgação do Conhecimento: Tendências, Limitações e os Desafios de Novas Estratégias, a obra reúne a contribuição de autores portugueses, espanhóis e latino-americanos, que além de analisarem aspetos cruciais dos mecanismos operativos internacionais de divulgação científica, apontam caminhos para romper barreiras e possibilitar uma maior democratização do conhecimento científico Ibero-Americano de Comunicação entre os seus próprios países e no mundo. Os 14 autores, aqui reunidos, preocupam-se em ecoar, na sociedade como um todo, as muitas vozes da América Latina e dos restantes países de línguas portuguesa, galega, catalã e espanhola que têm muito a dizer ao mundo todo por meio da investigação em Comunicação.
Effect of Interventions With a Clinical Decision Support System for Hospitalized Older Patients: Systematic Review Mapping Implementation and Design Factors
Authors: Damoiseaux-Volman Birgit A , van der Velde Nathalie , Ruige Sil G , Romijn Johannes A , Abu-Hanna Ameen , Medlock Stephanie
Published: July 2021

Background

Clinical decision support systems (CDSSs) form an implementation strategy that can facilitate and support health care professionals in the care of older hospitalized patients.

Objective

Our study aims to systematically review the effects of CDSS interventions in older hospitalized patients. As a secondary aim, we aim to summarize the implementation and design factors described in effective and ineffective interventions and identify gaps in the current literature.

Methods

We conducted a systematic review with a search strategy combining the categories older patients, geriatric topic, hospital, CDSS, and intervention in the databases MEDLINE, Embase, and SCOPUS. We included controlled studies, extracted data of all reported outcomes, and potentially beneficial design and implementation factors. We structured these factors using the Grol and Wensing Implementation of Change model, the GUIDES (Guideline Implementation with Decision Support) checklist, and the two-stream model. The risk of bias of the included studies was assessed using the Cochrane Collaboration’s Effective Practice and Organisation of Care risk of bias approach.

Results

Our systematic review included 18 interventions, of which 13 (72%) were effective in improving care. Among these interventions, 8 (6 effective) focused on medication review, 8 (6 effective) on delirium, 7 (4 effective) on falls, 5 (4 effective) on functional decline, 4 (3 effective) on discharge or aftercare, and 2 (0 effective) on pressure ulcers. In 77% (10/13) effective interventions, the effect was based on process-related outcomes, in 15% (2/13) interventions on both process- and patient-related outcomes, and in 8% (1/13) interventions on patient-related outcomes. The following implementation and design factors were potentially associated with effectiveness: a priori problem or performance analyses (described in 9/13, 69% effective vs 0/5, 0% ineffective interventions), multifaceted interventions (8/13, 62% vs 1/5, 20%), and consideration of the workflow (9/13, 69% vs 1/5, 20%).

Conclusions

CDSS interventions can improve the hospital care of older patients, mostly on process-related outcomes. We identified 2 implementation factors and 1 design factor that were reported more frequently in articles on effective interventions. More studies with strong designs are needed to measure the effect of CDSS on relevant patient-related outcomes, investigate personalized (data-driven) interventions, and quantify the impact of implementation and design factors on CDSS effectiveness.

Trial Registration

PROSPERO (International Prospective Register of Systematic Reviews): CRD42019124470; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=124470.
The Use of Person-Centered Language in Medical Research Journals Focusing on Psoriasis: Cross-sectional Analysis
Authors: Ottwell Ryan , Heigle Benjamin , Reddy Arjun K , Sajjadi Nicholas , Wirtz Alexis , Cook Courtney , Howard Hannah , Hartwell Micah , Vassar Matt
Published: July 2021

Background

Person-centered language places a person’s identity before any disability or medical condition they may have. Using person-centered language reduces stigma and improves the patient-physician relationship, potentially optimizing health outcomes. Patients with psoriasis often feel stigmatized due to their chronic skin condition.

Objective

We seek to evaluate the use of person-centered language in psoriasis literature and to explore whether certain article characteristics were associated with non–person-centered language.

Methods

We performed a systematic search on PubMed for recently published articles in journals that regularly publish psoriasis studies. After article reduction procedures, randomization, and screening, we reached our target sample of 400 articles. The following non–person-centered language terms were extracted from each article: “Psoriasis Patient,” “Psoriasis subject,” “Affected with,” “Sufferer,” “Suffering from,” “Burdened with,” “Afflicted with,” and “Problems with.” Screening and data extraction occurred in a masked duplicate fashion.

Results

Of the 400 included articles, 272 (68%) were not adherent to person-centered language guidelines according to the American Medical Association Manual of Style. The most frequent non–person-centered language term was “Psoriasis Patient,” found in 174 (43.5%) articles. The stigmatizing language was associated with the type of article and funding status, with original investigations and funded studies having higher rates of stigmatizing language.

Conclusions

Articles about psoriasis commonly use non–person-centered language terms. It is important to shift away from using stigmatizing language about patients with psoriasis to avoid potential untoward influences. We recommend using “patients with psoriasis” or “patient living with psoriasis” to emphasize the importance of person-centered care.
Telegentics and COVID 19 : Through the Pandemic and Beyond (Preprint)
Authors: Ravi Soumiya , Dhamija Radhika , Kocchar Aaina
Published: July 2021

BACKGROUND

The COVID 19 pandemic led to restrictions on the conventional ways of healthcare delivery. Telemedicine provided a viable solution that was in line with the social distancing policies imposed to minimize disease transmission. This demanded physicians adapt to new ways of healthcare delivery.

OBJECTIVE

We surveyed geneticists across the country to determine their experience and to ascertain if telegenetics will be a lasting change.

METHODS

A 23 item standardized survey was distributed to various US-based geneticists via email and other social media platforms focusing on their experience of providing care via telemedicine.

RESULTS

We received 69 responses from physicians across 26 states. Of these, 91% practiced in academia. 70% responded that pediatric genetics takes up more than 50% of their practice. 68% had over 50% of their practice switch to telemedicine. 77% felt they could provide adequate care via telemedicine and 94% of providers would like to continue telemedicine post-pandemic.

CONCLUSIONS

The future of telemedicine looks promising as the majority of clinicians would like to routinely use telemedicine post-pandemic. Uniform guidelines for use of telemedicine in genetics may need to be proposed by professional societies and supported by federal laws.
ECG Signal Classification Review
Authors: Fikri Muhammad Rausan , Soesanti Indah , Nugroho Hanung Adi
Published: July 2021

The heart is an important part of the human body, functioning to pump blood through the circulatory system. Heartbeats generate a signal called an ECG signal. ECG signals or electrocardiogram signals are basic raw signals to identify and classify heart function based on heart rate. Its main task is to analyze each signal in the heart, whether normal or abnormal. This paper discusses some of the classification methods which most frequently used to classify ECG signals. These methods include pre-processing, feature extraction, and classification methods such as MLP, K-NN, SVM, CNN, and RNN. There were two stages of ECG classification, the feature extraction stage and the classification stage. Before ECG features were extracted, raw ECG signal data first processed in the pre-processing stage because ECG signals were not necessarily free of noise. Noise will cause a decrease in accuracy during the classification process. After features were extracted, ECG signals were then classified with the classification method. Neural Network methods such as CNN and RNN are best to use since they can give better accuracy. For further research, the machine learning method needs to be improved to get high accuracy and high precision in the ECG signals classification.
Arduino based Bottle Sorting
Authors: Paranjpe Pushkar Prafulla
Published: July 2021

Automation has led to an increase in industries with new industries coming up each passing day,sorting naturally becomes an important process required in industries. Effective sorting and quality analysis systems can play a critical role in enhancing the quality of the product. Labour exaustion and increasing workload often leads to major errors in this field which may have adverse effects on the production of the company. This creates a need to design an effective sorting algorithm to overcome this problem and increase the overall productivity.A system which uses arduino, servo, ultrasonic sensor and conveyor is developed to overcome this problem and to ensure faultless outcome.
Experimental Study on Recycling of Bituminous Aggregate in Cement Concrete: A Research
Authors: Mishra Manoj Kumar
Published: July 2021

Recycling of bituminous aggregates in cement concrete has been selected for the present study to determine suitability of recycled material in road construction. This will help in achieving economy in road construction as well as saving on environment degradation in term of reduced mining and less pollution. Construction and maintenance of roads and highways involve millions of tonnes of aggregate. Considering the scarcity of fresh aggregate, replacement of part of the fresh aggregate with recycled aggregate is considered in the present study. Construction of the road is quite cost intensive. Material alone cost more than 60% of the total construction cost, out of which aggregate cost component, is approximately 30%. We can use recycled aggregate in place of fresh aggregate in construction of road and provide economy to the project. For making best use of recycled aggregates, it is essential to study the suitability of the same in various pavement components. In the present study recycled aggregate are used in Granular Sub Base (GSB) and Wet Mix Macadam (WMM).
Surgical Telementoring and Surginars with Added Virtual Layer using 5G Network
Authors: Verma Ankit
Published: July 2021

Healthcare sector has always been a key sector for social and economic well-being of any nation and since COVID-19 pandemic it has gained a center stage. Human resources are at the core of health care system. However, there is an acute shortage of doctors, nurses, and other health care workers. Brunt of scarce human resource is starker at specialization level. 5G network may provide a solution to this problem by human resource capacity building in some of the most complex areas of medical science. It may also provide an access to surgical expertise distributed globally. The low latency, high volume and high-speed data transfer allows sharing live surgical feed which may enhance the learning and assistance process. Hence, a synergy is achieved of physical and virtual world and a potential business model can be developed in such ecosystem. This work explores the requirements, architecture, implementation strategy, roles, and responsibilities of various stakeholders etc. to provide surgical expertise on a 5G network.