bluuebunny/crossref_metadata_2025 huggingface dataset:
Mandibular Magnet Retained Complete Overdenture
Authors: Chumaidi Glady , Dahlan Agus , Laksono Harry
Published: June 2020

Background: Complete denture in the lower jaw often has problems. The entire loss of the mandibular teeth often has a large resorption, so it is difficult to obtain retention and stability. Purpose: To report mandibular  magnet retained complete overdenture is can increase retention and stability in the lower jaw. Case: A 60-year-old man came to the Prosthodontics Clinic of RSGM Airlangga University with complaints of the old complete denture that made by previous dentist, is often unstable while talking and chewing, so the patient feel uncomfortable. The denture has been used for approximately four years. Therefore the patient wants to make a new complete denture. Case Management: PFM crown removed and 31,32,33,41,43 are treated with root canal treatment. Magnet keepers are fabricated on teeth 33,43, and metal copings are fabricated on teeth 31,32,41. The complete lower denture is attached to the magnet. Acrylic material denture are chosen. Discussion: Overdenture is a complete or partial denture that is placed above the tooth structure or the root of the original tooth which is the support of the denture. Overdenture treatment can maintain ridge height, reduced load of supporting elements, and avoid mucosal irritation. It’s necessary to add retention in the form of magnets to the teeth 33 and 43 to get good retention and stability. Conclusion: Mandibular  magnet retained complete overdenture is can increase retention and stability in the lower jaw so that the patient feels satisfied and comfortable because the dentures are more retentive and stable.
Sex determination using gonial angle during growth spurt period: a direct examination
Authors: Hariemmy Monica , Boedi Rizky Merdietio , Utomo Haryono , Margaretha Mieke Sylvia
Published: June 2020

Background: In forensic medicine and medicolegal, sex determination is an important step of an identification process. Parts of human skeleton that can be used for identification are cranium, pelvis, and mandible. There are several anthropometry tools in sex determination methods i.e shape of mandible, mental, gonial angle. Gonial angle in adults is an excellent tool for sex determination. However, bone density and masticatory force may change the value of gonial angle. Purpose: The objective of this study was to examine sex determination method using gonial angle in children during grow spurt period and external factors. Methods: There were 104 randomly selected subjects (51 boys and 53 girls) aged 7-12 years old. The subjects were grouped into prolonged sun exposure-hard diet (group A) and low sun exposure-soft diet (group B). The measurements were made using goniometer. Results: The mean of gonial angle of female children was greater than the male children. There was no significant difference between group A and B. Conclusion: Gonial angle can be used for sex determination in grow spurt period, and external factors did not affect sexual dimorphism.
Management Of Mandibular Lateral Incisor Agenesis With Skeletal Class III Malocclusion by Space Closing Technique
Authors: Inayati Fidiyah , Ardani I Gusti Aju Wahju
Published: June 2020

Background: Patients with congenital absence of a mandibular lateral incisor are often found having difficulty in achieving adequate functional occlusion. It may affect esthetics, mastication, speech, and occlusal balance. Purpose: This paper reported an agenesis treatment of one mandibular lateral incisor case using a space closure method. Case: A twenty-three years old female patient with agenesis of tooth 42, mandibular anterior crowding, multiple diastema on mandibular anterior teeth, and skeletal class III malocclusion. Case Management: Space closure method was chosen to correct the agenesis by considering the class III skeletal malocclusion and multiple diastema condition. Conclusion: Space closure method treatment improved the patient’s facial and dental esthetics, and it provided a good functional occlusion, despite the absence of a mandibular lateral incisor, which generally impairs the adequate incisal guidance.
POLITIK WACANA DI MEDIA SOSIAL TWITTER MENJELANG PEMILIHAN PRESIDEN INDONESIA 2014
Authors: Belawati Tian
Published: June 2020

Most of Indonesian politicians used internet and social media for campaign. The phenomena of twitwar, counter attack tweet, and black campaign using ironical and sarcasm words were massively appearing during presidential election which has been held in July 2014. The black campaign which was appearing pointed to represent characters of an actor or a candidate of president. This study is aimed to answer what topics written by cyber activists and politicians during January to April 2014, to find the discourse politics in representing the actors, and also to map the democratic action during campaign period in the twitter. The subjects of this study were twitter accounts of @Fadjroel, @PartaiSocMed, and @TrioMacan2000. The critical discourse analysis within critical linguistics approach by Theu Van Leeuwen was used to analyze the marginalization and the discourse politics. Theory of cyber culture, cyber sphere, and democratic in cyber space were used to be frameworks. The result tells that the sarcasm and ironical words were used to be discourse poltics in representing the actors. The ironical and sarcasm words were used as democratic form in social media which made youth as target readers considering youth were the most active users.
ETNOGRAFI DAYA MAGIS KERIS PUSAKA
Authors: Rudyanto Stefanus
Published: June 2020

Keris pusaka or heirloom keris is a heritage of culture from Indonesia. Speaking about keris pusaka, there are some perspectives, they are, philosophy, art, and magical power inside of it. This research is using ethnography methodology to comprehend the magical power in keris pusaka. The steps of methodology are similar to James P. Spradley’s that applied as grand theory in order to elaborate keris’ magical power with its abstract ambience. This research is reveals pengagem’s in various perspectives toward their keris pusaka and its magical power.
REALISME MAGIS DALAM NOVEL SIMPLE MIRACLE DOA DAN ARWAH KARYA AYU UTAMI
Authors: Mulia Sandra Whilla
Published: June 2020

This study are intend to reach some goals. First, this aimed to uncover the magic realism which is narrated in Ayu Utami’s novel, entitled Simple Miracle DoaDan Arwah. Second, this study aimed to discover socio cultural context which form the background of the emerging of magic realism of narrative in Ayu Utami’s novel entitled Simple Miracle Doa dan Arwah. This research utilizes magic realism narrative theory on the book Ordinary Enchantments Magical Realism andRemystifiction of Narratives written by Wendy B. Faris (2004). This is a qualitative study which employed textual analysis to analyze the obtained data. The results of 2 this study were magic realism which was narrated in the novel were not only loaded by the characteristics of Faris’ magic realism by showing the exquisite existence of myth in this modern era, but also written to be in charge of bracing and reorganizing people’s believe in Javanese myth. Socio cultural context which form the background of the emerging of this novel was Javanese culture that still exist in this modern era. This was also added by the comeback of traditional ambience which made its existence popular nowadays. From the analysis this had emerged two issues, social issues and signification issues. The emerging social issues are the Javanese culture in which the people tend to fancy mystics. These mystics are related to ghosts. In addition, the other issue is about acculturation of religions in Java Island. Besides the issues, the signification obtained were: (1) Javanese will always hold their believe in ghost; (2) in Java, shaman and spirits or ghost are correlated to the second alternative to realize dreams; (3) shaman identity is identical with someone who has an ability to see and communicate with spirits or ghosts; (4) there is a believe that spirits and ghosts are everywhere; (5) Javanese believe that every dead person will soon become spirits and ghosts and they will eternally live around them; (6) atheist will rarely be seen in Java; (7) religions in Java Island will always blend themselves with the culture.
DEKONSTRUKSI PERADABAN ISLAM DI AMERIKA PADA NOVEL BULAN TERBELAH DI LANGIT AMERIKA KARYA HANUM SALSABIELA RAIS DAN RANGGA ALMAHENDRA
Authors: Yusuf Abdul Aziz
Published: June 2020

Penelitian ini bertujuan untuk mengungkap dekonstruksi yang dilakukan oleh Hanum dan Rangga terhadap sejarah peradaban Islam di Amerika di dalam novel mereka yang berjudul Bulan Terbelah di Langit Amerika. Penelitian ini menggunakan teori dekonstruksi Jacques Derrida untuk melihat bagaimana mereka membalik posisi Islam di dalam oposisi biner. Metode simak-catat dilakukan untuk mengumpulkan data dari novel BTdLA. Tahap analisis data dibagi menjadi empat, yaitu: (1) klasifikasi, (2) reduksi, (3) analisis, dan (4) penarikan kesimpulan. Hasil penelitian dekonstruktif menunjukkan bahwa Hanum dan Rangga mendekonstruksi posisi Islam di Amerika di dalam novel mereka. Peradaban Islam yang awalnya dianggap tidak lebih dari imigran yang berada di dalam minoritas mereka balik sehingga mereka kemudian memiliki peran yang penting di dalam sejarah panjang Amerika Serikat. Hal ini mereka tunjukkan dengan besarnya peran kaum Morisco dalam membantu Christopher Columbus untuk menemukan benua Amerika. Mereka juga menunjukkan fakta-fakta bahwa kaum musafir muslim telah lama tiba dan membangun koloni di Amerika jauh sebelum Columbus tiba.
PERBANDINGAN REPRESENTASI ETNIS UIGHUR DI MEDIA BERITA CHINA DAILY DAN BBC
Authors: Wanting Sun , Karnanta Kukuh Yudha
Published: June 2020

Penelitian yang berjudul “Perbandingan representasi etnis Uighur di Media Berita China Daily dan BBC” ini dilakukan oleh peneliti untuk melihat citra etnis Uighur yang direpresentasikan oleh China Daily dan BBC. Metode penelitian ini menggunakan metode kualitatif dengan memanfaatkan pendekatan analisis wacana kritis model Teun A. Van Dijk terhadap analisis wacana media, yaitu melalui teks, kognisi sosial, dan konteks sosial dalam membongkar makna dibalik perbedaan representasi teks berita terkait isu etnis Uighur oleh kedua media tersebut. Hasil penelitian ini menunjukkan bahwa media berita online China Daily cenderung memberitakan etnis Uighur dalam perspektif eksotisme. Sementara itu, media berita online BBC memberitakan etnis tersebut secara lebih problematik. Perbedaan ini terjadi dikarenakan adanya pengaruh kognisi sosial dan konteks sosial para wartawan, seperti China Daily yang berada di bawah pengawasan Partai Komunis China dan BBC yang telah dipengaruhi oleh lingkungan sosialnya (sikap kritik).
IDENTITAS ETNIS DAN PROSES AKULTURASI ROHINGYA DI BANGKOK, THAILAND
Authors: Rangsikul Rungthum
Published: June 2020

Penelitian ini bertujuan untuk meneliti konstruksi identitas etnis Rohingya dan menemukan proses-proses penyesuaian diri mereka dalam pengungsiannya di Kota Bangkok Thailand melalui proses akulturasi. Dalam penelitian ini, saya berargumen bahwa pengalaman etnis Rohingya di negara Thailand dalam proses konstruksi identitas dan akulturasinya akan cenderung berbeda dengan negara tetanga lain berdasarkan budaya dan keyakinan. Perbedaan pengalaman ini selanjutnya menjadi dasar penelitian untuk melihat bagaimana change and continuities, berbagai perubahan dan hal-hal yang terus dipertahankan dalam konteks konstruksi identitas dan akulturasi etnis Rohingya sebagai bentuk adaptasi mereka di Bangkok. Populasi yang diteliti adalah Rohingya yang tinggal di kota Bangkok, Thailand. Wawancara mendalam digunakan untuk memperoleh data kualitatif dari lima responden Rohingya. Temuan utama adalah strategi akulturasi yang mencerminkan integrasi. Berhubungan dengan orang secara bertahap meningkatkan dari waktu ke waktu. Diskriminasi dianggap sebagai masalah problematik. Hidup dalam lingkungan yang berubah telah dimodifikasi tergantung pada konteks budaya, latar belakang individu, dan karakteristik sosial.
Abattage des porcs et qualités des carcasses et des viandes
Authors: MONIN G.
Published: June 2020

L’amélioration de la compétitivité des entreprises d’abattage de porcs ne repose plus essentiellement sur l’abaissement de leurs coûts, mais plutôt sur leur capacité à élever la qualité de leurs produits. La marge de progrès disponible la plus importante réside dans la part des opérations qui concerne les animaux vivants. Accroître la maîtrise des qualités de la viande implique nécessairement de mieux comprendre la réaction des animaux aux facteurs d’agression rencontrés lors de l’abattage, et ses effets sur ces qualités. Les connaissances disponibles dans ce domaine n’expliquent qu’une partie des mécanismes en cause, et il reste nécessaire de les approfondir, en portant particulièrement l’attention sur les interactions entre facteurs zootechniques et technologiques. D’une façon générale, il faut respecter un délai de 20 à 24 heures entre le dernier repas et l’abattage, prendre toutes les dispositions nécessaires pour minimiser les facteurs d’agression, en particulier un aménagement des locaux tenant compte des particularités comportementales du porc, et veiller à l’application optimale de l’anesthésie, qu’elle soit électrique ou gazeuse. Parmi les opérations succédant à l’abattage, la réfrigération est celle qui est susceptible de l’impact le plus marqué sur la qualité.
(only in French) Dossier : Systèmes d’élevage et typicité des produits laitiers
Authors: BERANGER C.
Published: June 2020

Depuis bientôt dix ans l’INRA, en relation avec l’INAO (Institut National des Appellations d'Origine), a engagé des recherches pour mieux comprendre et expliciter les qualités spécifiques des produits liées à leur origine géographique et justifiant leur protection juridique à travers les dénominations Appellation d’origine contrôlée (AOC) ou Indication géographique protégée (IGP). L’origine d’un produit n’est pas seulement sa provenance d’un lieu mais repose sur une série de liens plus ou moins étroits avec le territoire dont il est issu. Voir la suite de l'article à l'adresse : https://www6.inrae.fr/productions-animales_eng/content/download/3820/39523/version/1/file/Prod_Anim_2003_16_4_04.pdf
(only in French) Facteurs de succès des produits d’origine certifiée dans les filières agro-alimentaires en Europe : marché, ressources et institutions
Authors: BARJOLLE D. , SYLVANDER B.
Published: June 2020

Les produits d’origine certifiée établissent une différence par rapport aux produits standards présents sur le même marché. La notion de différenciation proposée par l’économie industrielle rejoint un premier sens de la notion de spécificité : le produit est dit différencié s’il a des caractéristiques particulières (mesurables, au sens de substantielles ou d’intrinsèques) et s’il est perçu comme tel par les usagers. Le concept économique de marché pertinent délimite les produits substituables aux yeux des consommateurs. Voir la suite de l'article à l'adresse suivante :https://www6.inrae.fr/productions-animales_eng/content/download/3824/39535/version/1/file/Prod_Anim_2003_16_4_08.pdf
(only in French) Dossier : Systèmes d’élevage et typicité des produits laitiers - Conclusions
Authors: BERANGER C.
Published: June 2020

Ce séminaire a rassemblé 38 personnes (24 chercheurs ou enseignants-chercheurs, 5 agents de l’INAO et 9 agents d’organismes professionnels ou économiques). La qualité et  la richesse des informations échangées et des discussions qu’elles ont suscitées ont permis d’atteindre en grande partie les objectifs affichés. La connaissance mutuelle entre participants de diverses équipes et disciplines, l’écoute des diverses approches et points de vue, les nombreux échanges formels ou informels, l’intensité des débats dans les ateliers et dans l’échange final entre ateliers, ont contribué à la création du réseau que nous voulons établir sur les AOC-IGP laitières et à la construction d’une culture commune sur le thème qui nous rassemble. Les principaux points forts à souligner sont les suivants. Voir la suite de l'article à l'adresse suivante :https://www6.inrae.fr/productions-animales_eng/content/download/3825/39538/version/1/file/Prod_Anim_2003_16_4_09.pdf
PRAZER E SOFRIMENTO NA POLÍCIA MILITAR
Authors: Marçal Hanna , Schlindwein Vanderléia
Published: June 2020

As transformações políticas e econômicas do estado brasileiro têm impactado diretamente nos investimentos na segurança pública do país. Situação que repercute negativamente na saúde do policial militar e favorece o sofrimento, expondo-o aos riscos físicos e psicossociais. Como objetivo o estudo buscou identificar nos artigos científicos brasileiros, publicados no período de 2008 a 2018, as implicações da organização e condições de trabalho nas vivências de prazer-sofrimento dos policiais militares e as repercussões à saúde física e mental. Utilizou-se as bases de dados: SciELO, Google Acadêmico, BDTD (Biblioteca Digital de Teses e Dissertações), Lilacs BVS e Periódicos Capes. Foram analisados vinte e quatro estudos. Observou-se que apesar dos policiais militares serem a principal barreira contra a criminalidade, o embate com a violência não é o fator protagonista das vivências que ressoam negativamente na vida desses indivíduos, os autores apontam para um adoecimento ligado a atual precarização do trabalho na Polícia Militar. Os constrangimentos advêm das condições de trabalho e da sua organização real de trabalho. O relato sobre o prazer no trabalho apareceu em estudos realizados com coletivos de policiamento especializado, o que sinaliza que as condições de trabalho diferenciadas propiciam um trabalho com vivências de prazer e ressignificação do sofrimento.
OS EFEITOS ADVERSOS CAUSADOS PELO USO DO CARBONATO DE LÍTIO EM PACIENTES COM TRANSTORNO BIPOLAR AFETIVO: UMA REVISÃO DA LITERATURA
Authors: Rodrigues Lima Neuenschwander Penha Saulo , Isidoro Bezerra Geovana Christina , Gonçalves Pereira Gabriella , Lopes Santana Vinicius , Couto de Souza Gomes Gleyssi , Sairo Porto de Melo Kairo , Macedo Abreu Leonardo
Published: June 2020

O transtorno bipolar afetivo se apresenta como fator de risco para o suicídio e ainda afeta não só o humor do indivíduo, mas suas relações interpessoais, repercutindo diretamente na sociedade. O carbonato de lítio é a droga de escolha para estes casos, todavia, ainda que o mesmo venha sendo utilizado há décadas, existe uma vasta gama de interações medicamentosas e efeitos colaterais devido ao uso do mesmo, principalmente devido ao baixo índice terapêutico desta droga. O presente artigo tem como objetivo, evidenciar os principais efeitos colaterais advindos do uso do carbonato de lítio em pacientes com transtorno bipolar afetivo. Trata-se de uma revisão sistemática da literatura, de caráter transversal, onde buscou-se nos principais bancos de dados de literatura científica. A revisão sistemática dos dados, resultou em quatro artigos considerados elegíveis mediante o atendimento do propósito do presente estudo e fatores de inclusão. Dever-se-á considerar os casos onde o paciente apresenta mais de um transtorno de comportamento, como a depressão, quadro bastante associado ao transtorno afetivo bipolar. Nestes casos, é comum a associação entre medicamentos psicoativos, o que pode gerar interações medicamentosas graves e de alta potência em causar danos ao paciente, como sintomas extrapiramidais e síndromes clínicas potencialmente fatais.  

Palavras-chave: Lítio. Interações Medicamentosas. Transtorno Bipolar.

ABSTRACT

Affective bipolar disorder presents as a risk factor for suicide and still affects not only the individual's mood, but their interpersonal relationships, directly affecting society. Lithium carbonate is the drug of choice for these cases; however, although it has been used for decades, there is a wide range of drug interactions and side effects due to the use of lithium carbonate, mainly due to the low therapeutic index of this drug. The present article aims to show the main side effects of the use of lithium carbonate in patients with affective bipolar disorder. It is a systematic review of the literature, of a transversal character, where it was searched in the main databases of scientific literature. The systematic review of the data, resulted in four articles considered eligible for the purpose of the present study and inclusion factors. Consideration should be given to cases in which the patient presents with more than one behavioral disorder, such as depression, which is strongly associated with bipolar affective disorder. In these cases, the association between psychoactive drugs is common, which can generate serious and high-potency drug interactions in causing harm to the patient, such as extrapyramidal symptoms and potentially fatal clinical syndromes.

Keywords: Lithium. Drug Interactions. Bipolar Disorder.
Time-Restricted Feeding Improves Body Weight Gain, Lipid Profile, and Atherogenic Indices in Cafeteria Diet-fed Rats: Role of Browning Inguinal White Adipose Tissue
Authors: Aouichat Samira , Bouguerra-Aouichat Souhila , Agil Ahmad
Published: June 2020

Time-restricted feeding (TRF) showed a potent effect in preventing obesity and improving metabolic outcomes in several animal model of obesity; however, there is, as yet, scarce evidence about its effectiveness against obesogenic challenge that more accurately mimic the human Western diets, such as cafeteria diet. Moreover, the mechanism for its efficacy is poorly understood. White adipose browning has been linked to body weight loss. Herein, we tested whether TRF has the potential to induce browning of inguinal white adipose tissue (iWAT) and to attenuate obesity and associated dyslipidemia in cafeteria diet-induced obesity model. Male Wistar rats, fed normal laboratory chow (NC) or cafeteria diet (CAF) for 16 weeks, were subdivided into two groups that were subjected to either ad libitum (ad lib, A) or TRF (R) for 8 hours per day. Rats under TRF regimen had a lower body weight gain and adiposity compared with their diet-matched ad lib rats, despite equivalent levels of food intake and locomotor activity. In addition, TRF improved the deranged lipid profile [total cholesterol (TC); triglycerides (TG); high density lipoprotein (HDL-c); low density lipoprotein (LDL-c)] and atherogenic indices [atherogenic index of plasma (AIP); atherogenic coefficient (AC); coronary risk index (CRI)] in rats fed CAF diet. Remarkably, TRF resulted in decreased size of adipocytes and induced emergence of multilocular brown-like adipocytes in iWAT of NC- and CAF-fed rats. Protein expression of browning markers, such as uncoupling protein-1 (UCP1) and peroxisome proliferator activated receptor gamma coactivator 1-alpha (PGC1α) in iWAT were also up-regulated in time restricted NC- or CAF-fed rats. These findings suggest that TRF regimen is an effective strategy to improve obesity and associated dyslipidemia induced by CAF-diet, probably via a mechanism involving WAT browning process.
Are Models Useful? Reflections on Simple Epidemic Projection Models and the Covid-19 Pandemic
Authors: Artzrouni Marc
Published: June 2020

In this paper we provide an ``expository overview" of classic epidemic projection models. Starting with the simple case of an epidemic that grows exponentially we then investigate ``compartmental" models. These assume that the growth of an infected population is limited endogenously by the size of the underlying pool of susceptibles. We then describe a new family of so-called "Exo-r" statistical models, which hinge on an exogenously driven growth rate of the infected population. This family, which can be used to model both infections and deaths, captures parsimoniously both the depletion of susceptibles and the effect of interventions such as lockdowns and ``social distancing". The model is used to fit numbers of Covid-19 infections in China. It is also used to model and project deaths in the United States. Results are used to inform a discussion on i) the challenges at hand and ii) the extent to which epidemic projection models may be useful despite being wrong.
Tissue Tectonics and the Multi-Scale Regulation of Developmental Timing
Authors: Busby Lara , Steventon Benjamin
Published: June 2020

Development encompasses processes that occur at multiple length-scales, includ- ing gene regulatory interactions, cell movements and reorganisation, cell signalling and growth. It is essential that the timing of events in all of these different processes are coordinated to generate well patterned tissues and organs. However, how the timing of intrinsic cell state changes is coordinated with events at the multi-tissue and whole organism level is unknown. Here, we argue that an important mechanism which accounts for integration of timing across levels of organisation is provided by tissue tectonics: i.e. how morphogenetic events driving tissue shape change result in the relative displacement of signalling and responding tissues and coordinate devel- opmental timing across scales. In doing so, tissue tectonics provides a mechanism by which the cell specification events intrinsic to cells can be modulated by the temporal exposure to extracellular signals. This exposure is in turn regulated by higher-order properties of the embryo such as their physical properties, rates of growth and the combination of dynamic cell behaviours impacting tissue morphogenesis. Tissue tec- tonics creates a downward flow of information from higher to lower levels of biological organisation, providing an instance of downward causation in development.
Influência da Variabilidade Meteo-Oceanográfica no Oceano Atlântico Sudoeste sobre a Pesca Tubarão-Azul, Prionace glauca (Linnaeus, 1758)
Authors: Mafra Evandro Oscar , Fiedler Fernando , Schramm Mathias
Published: June 2020

O Brasil possui cerca de 8.500 km de linha de litoral e um número razoável de ilhas, totalizando uma área de aproximadamente 3,5 milhões de km² de Zona Econômica Exclusiva (ZEE), que se estendo desde o Cabo Orange (5 ºN) até o Chuí (34 ºS). A pesca com espinhel superfície é uma modalidade pesqueira mundialmente utilizada em oceano aberto. Atualmente os principais portos que abrigam a frota espinheleira na região Sudeste em Santos (SP) e Itaipava (ES) e na região Sul a localidade de Itajaí e Navegantes (SC). O tubarão-azul, Prionace glauca (Linnaeus, 1758), é uma das espécies de elasmobrânquios pelágicos, mais capturadas pela frota de espinhel de superfície. O tubarão-azul, é considerado o abundante dentre os grandes tubarões pelágicos presentes no Oceano Atlântico. É uma espécie oceânica, altamente migratória, apresenta distribuição global, entre as latitudes de 60°N e 50°S, ocorrendo em águas tropicais e temperadas, predominantemente naquelas com temperaturas entre 12°C - 20°C. A presente estudo visa avaliar a influência da variabilidade meteo-oceanográfica no oceano atlântico sudoeste sobre a população de tubarão-azul, Prionace glauca (Linnaeus, 1758), capturada pela frota industrial no período de 1994-2018 na modalidade de espinhel de superfície. Para a elaboração do estudo serão analisados ​​os dados de desembarques mensais da frota espinheleira da região do Atlântico Sudoeste entre os anos 1994 - 2018.
Variação da Temperatura da Superfície do Mar no Oceano Atlântico Sul Durante Episódios de Zona de Convergência do Atlântico Sul Oceânica
Authors: Steil Monalisa , Leal de Quadro Mário Francisco
Published: June 2020

A Zona de Convergência do Atlântico Sul (ZCAS) faz parte dos sistemas meteorológicos presentes no Brasil, ocorrendo nos meses de primavera/verão e  consiste em uma banda de nebulosidade com eixo orientado de noroeste-sudeste que se inicia no sul da Amazônia e se estende até o Oceano Atlântico Sudoeste. Este sistema meteorológico contribui significativamente para o aumento dos índices pluviométricos, sendo muito importante para as regiões economicamente desenvolvidas do Brasil. Este trabalho foi desenvolvido com o objetivo de analisar a variação da temperatura da superfície do mar (TSM) devido a atividade deste sistema meteorológico quando ocorre configuração de ZCAS Oceânica, que é quando o sistema posiciona-se sobre o oceano.Para isto, serão comparadas imagens de satélite e variáveis atmosféricas associados a ZCAS com a variação da TSM do antes e após a atividade deste sistema meteorológico. Os resultados constataram que a TSM  abaixo das ZCAS estava com uma temperatura mais quente (até 1º C) antes do fenômeno se configurar, e decaiu em até 1º C após a atuação da ZCAS. Estudar as variações de temperatura da superfície do mar da ZCAS e adjacências são indispensáveis para iniciar trabalhos que visam compreender os  impactos no ambiente marinho.
Modeling Validation of Tubing Compaction for Rigless Well Plug and Abandonment
Authors: Tunget Bruce , Lu Pengyuan , Cammarano Andrea , Karimi Nader , Paul Manosh
Published: June 2020

Conventional well plug and abandonment (P&A) can sever and remove the tubing to access casing or leave it in situ when it does not interfere with providing a seal over an indefinite time frame. This paper assesses the viability of pushing rather than pulling severed production tubing to gain casing access. The P&A decision to push, pull, or leave the tubing in situ depends on confirming existing seals and then placing suitable sealants, such as cement, to keep the risks of future well leakages as low as reasonably practicable (ALARP). Pushing or compacting tubing into the liquid space of a well could be used with smaller rigless units, which cannot hoist the production tubing, but can use production intervention or decommissioning logistics with coiled tubing or wireline cutting and severance. Associated pumps could then drive an inflatable piston to compact split and severed tubing into a lower liquid space to access casing for logging and P&A plugging. Rigless tools and methods have provided dramatic cost savings where casing access was not needed, and thus the present study investigates the viability of accessing casing by means of pushing or compacting tubing to extend rigless P&A use and savings. The viability of pushing and compacting North Sea sizes and grades were confirmed in real-scale physical-compaction simulations of production-tubing joints pulled from offshore wells. Independent small-scale physical simulations and numerical modeling then confirmed that the real-scale results were predictable and repeatable to demonstrate an ability to design and provide a window or gap in a production-tubing string for use by other P&A methods.
‘Motivational work’: a qualitative study of preventive health dialogues in general practice
Authors: Broholm-Jørgensen Marie , Langkilde Siff Monrad , Tjørnhøj-Thomsen Tine , Pedersen Pia Vivian
Published: June 2020

Background The aim of this article is to explore preventive health dialogues in general practice in the context of a pilot study of a Danish primary preventive intervention ‘TOF’ (a Danish acronym for ‘Early Detection and Prevention’) carried out in 2016. The intervention consisted of 1) a stratification of patients into one of four groups, 2) a digital support system for both general practitioners and patients, 3) an individual digital health profile for each patient, and 4) targeted preventive services in either general practice or a municipal health center.Methods The empirical material in this study was obtained through 10 observations of preventive health dialogues conducted in general practices and 18 semi-structured interviews with patients and general practitioners. We used the concept of ‘motivational work’ as an analytical lens for understanding preventive health dialogues in general practice from the perspectives of both general practitioners and patients.Results We found that the health dialogues occurred as one-way communication characterized by biomedically based guidance, information, suggestions, and advice on risk factors passed on from the general practitioner to the patient. Further, contextual factors relating to the intervention framework, the general practitioners’ perceptions of their professional position as well as the patients’ understanding of prevention —in an interplay—diminished the motivational work carried out in the health dialogues.Conclusion The findings show that the influence of different kinds of context adds to the complexity of prevention in the clinical encounter which help to explain why motivational work is difficult in general practice.
Would large dataset sample size unveil the potential of deep neural networks for improved genome-enabled prediction of complex traits? The case for body weight in broilers.
Authors: Passafaro Tiago Luciano , Lopes Fernando B. , Dórea João R. R. , Craven Mark , Breen Vivian , Hawken Rachel J. , Rosa Guilherme J. M.
Published: June 2020

Background: Deep neural networks (DNN) are a particular case of artificial neural networks (ANN) composed by multiple hidden layers, and have recently gained attention in genome-enabled prediction of complex traits. Yet, few studies in genome-enabled prediction have assessed the performance of DNN compared to traditional regression models. Strikingly, no clear superiority of DNN has been reported so far, and results seem highly dependent on the species and traits of application. Nevertheless, the relatively small datasets used in previous studies, most with fewer than 5,000 observations may have precluded the full potential of DNN. Therefore, the objective of this study was to investigate the impact of the dataset sample size on the performance of DNN compared to Bayesian regression models for genome-enable prediction of body weight in broilers by sub-sampling 63,526 observations of the training set.Results: Predictive performance of DNN improved as sample size increased, reaching a plateau at about 0.32 of prediction correlation when 60% of the entire training set size was used (i.e., 39,510 observations). Interestingly, DNN showed superior prediction correlation using up to 3% of training set, but poorer prediction correlation after that compared to Bayesian Ridge Regression (BRR) and Bayes Cπ. Regardless the amount of data used to train the predictive machines, DNN displayed the lowest mean square error of prediction compared to all other approaches. The predictive bias was lower for DNN compared to Bayesian models regardless the amount of data used with estimates closed to one with larger sample sizes. Conclusions: DNN had worse prediction correlation compared to BRR and Bayes Cπ, but improved mean square error of prediction and bias relative to both Bayesian models for genome-enabled prediction of body weight in broilers. Such findings, highlights advantages and disadvantages between predictive approaches depending on the criterion used for comparison. Nonetheless, further analysis is necessary to detect scenarios where DNN can clearly outperform Bayesian benchmark models.
Assessment of exercise-induced stress by automated measurement of salivary cortisol concentrations within the circadian rhythm in Japanese female long-distance runners
Authors: Ushiki Kazumi , Tsunekawa Katsuhiko , Shoho Yoshifumi , Martha Larasati , Ishigaki Hirotaka , Matsumoto Ryutaro , Yanagawa Yoshimaro , Nakazawa Asuka , Yoshida Akihiro , Nakajima Kiyomi , Araki Osamu , Kimura Takao , Murakami Masami
Published: June 2020

Background: Overtraining syndrome, caused by prolonged excessive stress, results in reduced performance and cortisol responsiveness in athletes. It is necessary to collect saliva samples sequentially within circadian rhythm for assessing exercise stress by measuring cortisol concentrations, and automated cortisol measurements using electrochemiluminescence immunoassay (ECLIA) may be useful for measuring a large number of saliva samples. In this study, we evaluated the appropriate use of cortisol-based exercise stress assessment within the circadian rhythm, which may diagnose and prevent overtraining syndrome in athletes. Methods: We collected saliva and sera from 54 healthy participants and analyzed the correlation between salivary cortisol concentrations measured by ECLIA and enzyme-linked immunosorbent assay (ELISA) or serum cortisol analysis. We also collected saliva continuously from 12 female long-distance runners on 2 consecutive days involving different intensities and types of exercise early in the morning and in the afternoon and measured salivary cortisol concentrations using ECLIA. Each exercise intensity of runners was measured by running velocities, Borg Scale score, and rate of change in the pulse rate by exercise. Results: ECLIA-based salivary cortisol concentrations correlated positively with those detected by ELISA (ρ = 0.924, p < 0.001) and serum cortisol (ρ = 0.591, p = 0.001). In long-distance runners, circadian rhythm of salivary cortisol including peak after waking and decrease promptly thereafter were detected on both days by continuous saliva sampling. The rates of change in salivary cortisol concentrations were significantly lower after an early morning exercise than after an afternoon exercise on both days (day 1, p = 0.002 and day 2, p = 0.003). In the early morning exercise, the rate of change in salivary cortisol concentration was significantly higher on day 1 than on day 2 ( p = 0.034), similar to significant difference in running velocities ( p = 0.001).Conclusions: Our results suggest that automated ECLIA-based salivary cortisol measurements are able to detect the athletes' circadian rhythm and compare the exercise stress intensities at the same times on different days, even in the early morning, possibly leading to prevention of overtraining syndrome.
Rates, predictors and mortality of sepsis-associated acute kidney injury: systematic review and meta-analysis
Authors: Liu Jie feng , Xie Hebin , ye ziwei , Wang Lesan
Published: June 2020

Objective:The incidence and mortality of sepsis-induced acute kidney injury is high. Many studies have explored the causes of sepsis-induced acute kidney injury (AKI). However, its predictors are still uncertain; additionally, a complete overview is missing. A systematic review and a meta-analysis were performed to determine the predisposing factors for sepsis-induced AKI. Method: A systematic literature search was performed in the Medline, Embase, Cochrane Library, PubMed and Web of Science databases, with an end date parameter of May 25, 2019. Valid data were retrieved in compliance with the inclusion and exclusion criteria. Result: Forty-seven observational studies were included for analysis. A cumulative number of 55911sepsis patients were evaluated. The incidence of AKI caused by septic shock is the highest. 30 possible risk factors were included in the meta-analysis. The results showed that 20 factors were found to be significant. The odds ratio(OR),95% confidence interval (CI) and Prevalence of the most prevalent predisposing factors for sepsis-induced AKI were as the following: Septic shock[2.88(2.36-3.52), 60.47%], Hypertension[1.43(1.20-1.70),38.39%), Diabetes mellitus[1.59(1.47-1.71),27.57%],Abdominal infection[1.44(1.32-1.58),30.87%], Vasopressors use[2.95(1.67-5.22),64.61%],vasoactive drugs use [3.85(1.89-7.87),63.22%], Mechanical ventilation[1.64(1.24-2.16),68.00%), Positive blood culture[1.60(1.35-1.89), 41.19%], Smoke history[1.60(1.09-2.36),43.09%]. Other risk factors include cardiovascular, coronary artery disease, liver disease, unknow infection, diuretics use, ACEI or ARB, gram-negative bacteria and organ transplant. Conclusion: A large number of factors are associated with AKI development in sepsis patients. Our review can guide risk-reducing interventions, clinical prediction rules, and patient-specific treatment and management strategies for sepsis-induced acute kidney injury.
Principles of “Humanistic Environment” in Dental Education: Design, Validation, and Standardization of a Questionnaire
Authors: Mehrnia Nika , Sadeghipour Maryam , Zafarmand A. Hamid
Published: June 2020

Background

Health science education for students should comply with the principles of the Humanistic Environment. Adhering to these principles, along with other didactic and clinical training courses, will make treatment more successful and brings more satisfaction for patients.
Methods

Six completely related researches were found in the literature (Pubmed, Google Scholar). A questionnaire consisting of 67 questions was collected for evaluation. The questionnaire was submitted to 9 members of a panel of experts for a survey. Using statistical methods, Content Validity Index (CVI) and Content Validity Ratio (CVR) were determined and its reliability was evaluated. According to the relevant formula and Lawshe table questions with a score higher than 0.79 and 0.78 were included in the questionnaire, respectively. The questionnaire was also administered to 8 students for determining the Face Validity. Cronbach's Alpha was calculated 0.808, using SPSS (v.#22) software. The Reliability Analysis was determined based upon 15 students’ opinions.
Results

Eventually, a questionnaire containing 39 questions was finalized and categorized in 7 eminent humanistic fields. These are: Internal Feelings, Rules and Regulations, Interpersonal Relations, Behavior Change, Administration, Commitment & Satisfaction, Professional Ethics.
Conclusions

The principles of Humanistic Environment provide favorable interaction between students and teachers, satisfy the welfare of patient, and succeed the outcome of treatment along with regular scientific courses. Due to cultural and social differences, a specific questionnaire should be designed for each community to reflect their interests.
Effect of bendiocarb based (Ficam® 80% WP) Indoor Residual Spraying on feeding patterns from malaria vectors in Burkina Faso, West Africa.
Authors: HIEN Sawdetuo Aristide , Soma Dieudonné Diloma , Sawadogo Simon Pengwende , Poda Serge Bèwadéyir , Namountougou Moussa , Ouédraogo Georges Anicet , Diabaté Abdoulaye , Dabiré Roch Kounbobr
Published: June 2020

Background: The fight against vector is essential in malaria prevention strategies in several endemic countries in Africa. In Burkina Faso, malaria transmission is seasonal in most parts of country, so a single round of spraying should provide effective protection against malaria, provided the insecticide remains effective over the entire malaria transmission season. The outcomes of indoor residual spraying towards curtailing malaria transmission are firstly to decrease the life span of vector mosquitoes and also to reduce the malaria vectors density.Methods : CDC light trap and early morning collections by pyrethrum spray catches were performed monthly to determine the change in malaria vector indices in sprayed (Diebougou) and unsprayed sites (Dano). The female’s malaria vectors collected by both methods were used to determine their blood feeding, biting and sporozoites rate and malaria transmission risk estimated by entomological inoculation rate.Results: Anopheles gambiae complex composed to Anopheles gambiae, Anopheles coluzzii and Anopheles arabiensis were present throughout the transmission season, but An. gambiae was the predominant species collected (P =0.0005), comprising 88% of the total collected and the most infected species. Malaria vectors densities were significantly lower in sprayed villages (n=4,303) compared with unsprayed villages (n=12,569) during post-spraying period (P = 0.0012). In addition, mean human biting rate of An. gambiae sl and An. funestus sl were significantly lower in sprayed areas compared to unsprayed areas (P<0.05). Overall, malaria vector transmission risk was significant lower in villages which received IRS (P=0.0001) whatever the malaria vectors species (An. gambiae sl and An. An. funestus sl).Conclusions: The results showed that in the sprayed area (Diebougou), vector densities, human biting rates and malaria transmission risks were very lower than unsprayed areas (Dano). The findings also showed a change in vector behavior especially within An. funestus which became more zoophagic following IRS. The indoor residual spraying could be recommanded as control tool in areas where malaria transmission occured a given period of year.
Therapeutic effects of Zuojin Pill on Helicobacter pylori-induced chronic atrophic gastritis through JMJD2B/COX-2/VEGF signaling axis
Authors: Wu Shihua , Bao Chunmei , Wang Ruilin , Zhang Xiaomei , Gao Sijia , Qin Weihan , Zhang Jianzhong , Zhang Juling , Li Ruisheng , Chen Xing , Wen Jianxia , Yang Tao , Wei Shizhang , Li Haotian , Wei Ying , Ren Sichen , Xia Houlin , Zhao Yanling
Published: June 2020

Background: Zuojin Pill (ZJP), a famous Chinese medicinal formula, widely accepted for treatment of chronic atrophic gastritis (CAG) in China. This study aimed to explore the therapeutic effects and mechanisms of ZJP in Helicobacter pylori (H. pylori) - induced chronic atrophic gastritis (CAG) in vivo and in vitro. Methods: CAG rat model was induced by H. pylori. ZJP (0.63, 1.26, and 2.52 g/kg, respectively) was administered orally for four weeks. Therapeutic effects of ZJP were identified by H&E staining and serum indices. In addition, cell viability, morphology and proliferation were detected by cell counting kit-8 (CCK8) and high-content screening assay (HCS), respectively. Moreover, relative mRNA expression and protein expression related to JMJD2B/COX-2/VEGF axis was detected to investigate the potential mechanisms of ZJP in CAG. Results: Results showed the symptoms (weight loss and gastric mucosa damage) of CAG were alleviated, and the contents of TNF-α in serum was markedly decreased after treating with ZJP. Moreover, cell viability, proliferation and morphology changes of GES-1 cells were ameliorated by ZJP intervention. In addition, proinflammatory genes and JMJD2B/COX-2/VEGF axis related genes were suppressed by ZJP administration in vitro and in vivo. Meanwhile, immunohistochemistry (IHC) and western blot confirmed down-regulation of these genes by ZJP intervention. Conclusion: ZJP treatment can alleviate gastric mucosal damage induced by H. pylori via JMJD2B/COX-2/VEGF axis.