bluuebunny/crossref_metadata_2025 huggingface dataset:
Analisis Geologi Teknik Longsor di Desa Kuatae, Kecamatan Kota Soe, Nusa Tenggara Timur
Authors: Syaeful Heri , Kamajati Dhatu , Rachael Yoshi , Damaledo Ebenheser
Published: August 2021

ABSTRAK Bencana alam longsor di Desa Kuatae, Kecamatan Kota Soe sering terjadi pada musim hujan. Longsor telah menyebabkan rusaknya rumah dan infrastruktur lainnya. Penelitian longsor dilakukan dengan pemetaan geologi teknik, pengeboran geologi teknik, uji laboratorium, analisis kestabilan lereng, dan identifikasi opsi penanggulangan. Berdasarkan hasil pemetaan, longsor terjadi dalam dua model, yaitu blok batugamping terumbu yang mengalami longsor translasi di atas napal dan batulempung serta longsor rotasi pada napal yang dikontrol oleh lapisan dasar yang kontak dengan batulempung. Hasil uji penetrasi standar pada batulempung dan napal menunjukkan nilai konsistensi yang sangat tinggi. Hasil analisis kestabilan lereng menunjukkan lereng dalam keadaan stabil tapi ternyata longsor masih terjadi di beberapa tempat pada area napal dan batulempung. Hal tersebut mengindikasikan bahwa material batuan mengalami degradasi kuat geser pada beberapa kondisi. Penelitian lebih lanjut terkait degradasi material batuan, seperti sifat tahan lekang dan lempung mengembang sangat penting untuk menentukan opsi penanggulangan yang paling tepat dilakukan pada kasus longsor di Desa Kuatae.ABSTRACT Landslides in Kuatae Village, Kota Soe District often occur during the rainy season. The slope failures cause damage to houses and other infrastructures. The research of slope failure has been carried out by using engineering geological mapping, engineering geological drilling, laboratory test, slope stability analysis, and identification of countermeasure options. Based on the mapping results, slope failures occur in two models, the first one was coral limestone blocks translation failure over marl and claystone, and the second one was rotation failure on marl that controlled by the base layer which contact with claystone. The result of the standard penetration test on claystone and marl showed a very high consistency value. The slope stability analysis had shown the slope is in a stable state, but slope failure occurred in several places on the marl and claystone area. Those indicated that the material had encounter shear strength degradation under several circumstances. Further investigation on the degradation of the rock material, such as slake durability and swelling clay are very important to determine the most appropriate countermeasure option to be applied in the landslide case of Kuatae Village.
Identifikasi Deformasi Tektonik Aktif Berdasarkan Ekstraksi Kelurusan Morfologi dan Seismisitas di Sukabumi, Jawa Barat
Authors: Mahbub Rizqi Muhammad , Ragil Candra
Published: August 2021

ABSTRAK Pusat gempa bumi di Sukabumi telah membentuk deformasi bawah permukaan dan kini terekam juga di permukaan. Hal itu termanifestasi melalui geomorfologi kelurusan gawir dan sungai. Ekstraksi kelurusan-kelurusan akibat deformasi geologi tersebut dapat digunakan untuk mengidentifikasi deformasi tektonik aktifnya. Tujuan penelitian ini adalah untuk mengetahui hubungan antara struktur sesar aktif dengan arah dominan kelurusan di daerah penelitian. Metode Edge Enhancing Filtering digunakan untuk menginterpretasi kelurusan secara manual dan semi-otomatis. Data geospasial kelurusan diekstraksi menggunakan formula Sastratenaya untuk mengetahui kronologi kelurusan yang terbentuk. Hasil analisis menggunakan formula Sastratenaya menunjukkan kelurusan-kelurusan yang terekam melalui olah data peta DEM, yaitu segmen 1 berarah N315°E dan segmen 2 berarah N10°E yang diinterpretasikan sebagai hasil reaktivasi sesar. Hal ini dapat diinterpretasikan bahwa Sesar Cimandiri, yang merupakan sesar aktif dengan pergerakan oblique-slip sinistral N88°E/85° rake 33°, memengaruhi arah dua segmen kelurusan di daerah penelitian wilayah Sukabumi, Jawa Barat.ABSTRACT The epicenter of the earthquake in Sukabumi has formed subsurface deformation which is now also recorded on the surface area. This is manifested through the geomorphology of the scarp and river lineaments. Extraction of lineaments produced by geological deformation can be used to identify its active tectonic deformation. The research objective is to determine the relationship between the active fault structure and the dominant direction of lineaments in the study area. The Edge Enhancing Filtering method is used to interpret lineaments manually and semi-automatically. The lineament geospatial data was extracted using the Sastratenaya formula to determine the chronology of the lineaments formed. The Sastratenaya formula results showed the lineaments recorded by DEM images data processing, the first segment direction is N315°E and the second is N10°E, both are interpreted as the result of fault reactivation. It can be interpreted that the Cimandiri Fault, which is an active fault that has an N88°E/85° rake 33° sinistral oblique-slip fault movement, affects the lineaments direction of two segments in the research area of Sukabumi, West Java.
Karakteristik Geokimia Basal Alkali Formasi Manamas di Sungai Bihati, Baun, Pulau Timor
Authors: Widiatama Angga Jati , Santy Lauti Dwita , Natalia Happy Christin , Wahyudiono Joko , Ikhram Rinaldi
Published: August 2021

ABSTRAK Batuan beku Formasi Manamas di Sungai Bihati, Baun merupakan salah satu singkapan batuan beku di Pulau Timor yang belum banyak diteliti berdasarkan karakter geokimia. Penelitian ini bertujuan untuk mengetahui genesa dan proses yang terjadi pada batuan beku Formasi Manamas dalam kerangka tektonik yang terjadi di Pulau Timor berdasarkan analisis petrografi dan geokimia. Analisis geokimia dilakukan dengan menggunakan X-ray Fluorescence (XRF) dan Inductively Coupled Plasma-mass Spectrometery (ICP-MS) untuk mengetahui senyawa utama, unsur jejak, dan unsur tanah jarang. Batuan beku Formasi Manamas berupa intrusi basal dengan afinitas alkali yang menunjukkan pola pengayaan unsur tanah jarang yang identik dengan Ocean Island Basalt (OIB). Penelitian ini membuktikan adanya dua mekanisme pengayaan unsur yang berbeda yaitu fluid related enrichment yang berkaitan dengan aktifitas subduksi lempeng Samudra Hindia di bawah Busur Banda dan melt related enrichment yang diperkirakan berasal dari sisa lempeng Samudra Hindia yang patah yang masuk kedalam zona reservoir OIB. Kedua magma lalu bercampur dan mengalami underplating di bawah Busur Banda. ABSTRACT The igneous rock of Manamas Formation in the Bihati River, Baun is one of the igneous rock outcrops in Timor Island that has not been widely studied based on its geochemical characteristic. This study aims to determine the genesis and processes that occur in the igneous rocks of the Manamas Formation within tectonic framework of Timor Island based on petrographic and geochemical analysis. X-ray Fluorescence (XRF) and Inductively Coupled Plasma-mass Spectrometery (ICP-MS) were used to determine the major elements, trace elements, and rare earth elements. The igneous rock of the Manamas Formation is a basalt intrusion with an alkaline affinity which shown an enrichment pattern of rare earth elements identical to Ocean Island Basalt (OIB). This study proves the existence of two different mechanisms of elemental enrichment, fluid related enrichment which related to the subduction activity of the Indian Ocean plate under the Banda Arc and also melt related enrichment which originated from the broken Indian Ocean plate which enters the OIB reservoir zone. The two different magmas then mix and underplating beneath the Banda Arc.
Mikrozonasi di Daerah Plampang, Nusa Tenggara Barat
Authors: Iswanto Eko Rudi , Riyanto Theo Alvin , Suntoko Hadi
Published: August 2021

ABSTRAK Provinsi Nusa Tenggara Barat (NTB) merupakan daerah dengan aktivitas kegempaan yang tinggi. Fenomena ini disebabkan oleh adanya aktivitas tektonik sebagai akibat pertemuan Lempeng Eurasia-Australia (zona subduksi) di bagian selatan dan Sesar Flores di bagian utara serta adanya keberadaan sesar-sesar lokal. Terkait dengan rencana pengembangan kawasan Samota di Pulau Sumbawa, NTB, perlu dilakukan suatu kajian kegempaan. Tujuan penelitian ini adalah memetakan indeks kerentanan seismik (Kg) melalui pengukuran mikrotremor dengan analisis menggunakan metode Horizontal to Vertical Spectral Ratio (HVSR). Hasil penelitian berupa peta kerentanan seismik daerah Plampang yang menunjukkan bahwa sisi utara lokasi penelitian memiliki indeks kerentanan seismik rendah yang ditandai dengan nilai amplifikasi kurang dari tiga jika dibandingkan daerah lainnya. Geologi sisi utara lokasi penelitian tersusun oleh batuan gunung api dengan karakteristik batuan keras, ketebalan sedimen sangat tipis, dan tersusun atas batuan Tersier atau lebih tua. Peta kerentanan seismik berguna sebagai acuan dalam mitigasi gempa bumi untuk mengurangi risiko yang ditimbulkan. ABSTRACT Nusa Tenggara Barat (NTB) Province is an area with intense seismic activity. This phenomenon is caused by tectonic activity as the result of the convergency of the Eurasia-Australia Plates (subduction zone) in the south and the Flores Fault in the north as well as the presence of local faults. Regarding the plan to develop the Samota area in Sumbawa Island, NTB, a study concerning earthquakes should be done. The purpose of this study is to map the seismic vulnerability index (Kg) through microtremor measurement by using the Horizontal to Vertical Spectral Ratio (HVSR) analysis method. The result of the study is a seismic vulnerability map of the Plampang area which its northern part has a low seismic vulnerability index indicated by the amplification factor value of less than three compared to other areas. The geology of the northern part of the Plampang area consists of volcanic rocks which has hard rock characteristic, very thin sediment thickness, and composed of Tertiary or older rocks. Seismic vulnerability maps can be useful as a reference for earthquake mitigation to reduce its risks.
Yeast growth and fluorescence 96-well plate reader experiment, set up from a 96 deep well plate v1
Authors: Auxillos Jamie , Alibert Clémence , Wallace Edward
Published: August 2021

This protocol is used to measure a time-series of growth and fluorescence output in yeast. We have used it on S288C-background Saccharomyces cerevisiae yeast expressing a range of fluorophores, from a fluorescent reporter gene or tagged protein. It can also be used to measure growth alone if no fluorophore is present. Precisely, the protocol describes the measurement of yeast absorbance (OD600) and fluorescence output in a microtiter plate over 12-15 hours in a Tecan Infinity M200 series plate reader. We have also run essentially the same protocol on a fixed-wavelength F200 plate reader. The pre-culture of the cells was carried out on a 96 deep well plate. On the following day, the preparation and culturing of the cells on a black microtiter plate was carried out mostly according the protocol described in Lichten et al. (2014). 1. Lichten CA, White R, Clark IB, Swain PS. Unmixing of fluorescence spectra to resolve quantitative time-series measurements of gene expression in plate readers. BMC Biotechnol. 2014 Feb 3;14:11. doi: 10.1186/1472-6750-14-11.
Golden Gate Assembly (Esp31 or Bsa1 v2 HF) v1
Authors: Auxillos Jamie , Wallace Edward
Published: August 2021

This protocol is for the assembly of DNA parts using Golden Gate assembly (Engler et al. 2008) with modifications from on publication by Garcia-Ruiz et al. (2018) and online resource by NEB (https://international.neb.com/protocols/2018/10/02/golden-gate-assembly-protocol-for-using-neb-golden-gate-assembly-mix-e1601). Parts can either be assembled by Golden Gate assembly using Esp31 or Bsa1v2-HF depending on the restriction sites flanking the parts. Using this protocol, multiple insert parts can be assembled into the parts acceptor vector. The Golden Gate assembly reaction is incubated in a thermocycling program set at a digestion temperature of at 37℃ and ligation temperature of 16℃ for 20-30 cycles. The reaction is subsequently transformed into E. coli cells (DH5ɑ, Mach1, TOP10, NEB10β). 1. EnglerC, KandziaR, MarillonnetS (2008)A One Pot, One Step, Precision Cloning Method with High Throughput Capability. PLOS ONE 3(11): e3647. doi: 10.1371/journal.pone.0003647 2. Garcia-Ruiz E, Auxillos J, Li T, Dai J, Cai Y. YeastFab: High-Throughput Genetic Parts Construction, Measurement, and Pathway Engineering in Yeast. Methods Enzymol. 2018;608:277-306. doi: 10.1016/bs.mie.2018.05.003.
The role of computed and magnetic resonance imaging in assessment of the local advancement of malignant tumors of the hearing organ
Authors: Khazarova E. G. , Dronova E. L.
Published: August 2021

Introduction. Сomputed tomography (СТ) and magnetic resonance imaging (MRI) are the main methods of radiological diagnostics, which makes it possible to objectively assess the local advancement of malignant tumors of the hearing organ and decide on the possibility of surgical intervention.

The objective of this scientific research – to determine the main indications for surgical intervention, taking into account the radiological criteria for the lesion of the temporal bone (CT, MRI) in locally advanced outer ear skin cancer. Materials and methods. This research work based on a retrospective and prospective analysis case history for patients with locally advanced external ear skin cancer. These are 45 patients, who received treatment in surgical department of head and neck tumors in N. N. Blokhin National Medical Research Center of Oncology between 1994 and 2020. Patient observation time averaged 30.0 ± 32.3 months (from 0.7 to 117.4 months, median – 12.0 months).

Results. The prevalence of the tumor process in cancer of the skin of the external auditory canal in accordance with the staging system for lesions of the temporal bone structures (University of Pittsburgh, 1990), which takes into account CT and MRI signs of damage to the temporal bone and adjacent anatomical structures, is a factor that significantly affects the long-term results of treatment (for disease-free survival: hazard ratio (HR) 4.76, 95 % confidence interval (CI) 1.93–11.73, р = 0.00069; for tumor-specific survival: HR 4.25, 95 % CI 1.74–10.39, р = 0.0015; for overall survival: HR 1.96, 95 % CI 1.07–3.58, р = 0.029).

Conclusion. CT and MRI are mandatory methods of radiological diagnosis of patients with skin cancer of the external auditory canal.
Correction of eating disorders in patients with oral and oropharyngeal cancer after reconstructive plastic surgery
Authors: Krasavina E. A. , Choynzonov E. L. , Kulbakain D. E. , Aleekseev V. A.
Published: August 2021

The study objective – to evaluate the feasibility of correcting eating disorders in patients undergoing surgery for oral and oropharyngeal cancers using various reconstructive techniques to restore postoperative defects.

Materials and methods. Between 2012 and 2019, a total of 56 patients with stage II–IV oral and oropharyngeal cancer underwent reconstructive surgery after either hemiglossectomy or glossectomy. The patients ranged in age from 26 to 70 years. The patients were divided into two groups. Group I consisted of 36 (64.3 %) patients who underwent tongue reconstruction using rotation flaps. For reconstruction of hemiglossectomy defects, a chin flap was used, and for reconstruction of glossectomy defects, a pectoral flap was used. Group II comprised 20 (35.7 %) patients who underwent tongue reconstruction using free revascularized flaps. For the tongue reconstruction after hemiglossectomy, the radial flap, medial sural perforator flap and fasciocutaneous anterolateral thigh flap were used. For the tongue reconstruction after glossectomy, the fasciocutaneous anterolateral thigh flap was used. The acts of chewing and swallowing were restored during speech rehabilitation due to the activation and coordination of the work of the muscles of the cheeks, lips, soft palate, pharynx, and the reconstructed tongue. Eating disorders were assessed by interviewing patients. A comparative analysis of eating disorders included mobility and coordination of facial muscles and reconstructed tongue, increased sensitive in the oral cavity, the presence of aspiration and nasal regurgitation, and subjective difficulties of patients. The time before the start of rehabilitation and its duration were taken into account. Patients were interviewed before the start of the combined treatment, at the beginning and after the completion of rehabilitation.

Results. After the completion of rehabilitation, all patients received food by the oral route. The best outcomes were achieved in group 2a patients, who underwent tongue reconstruction with free revascularized flaps. This group of patients had a lower percentage of the asymmetry of facial muscles and limited mobility of the tongue compared to other groups of patients.

In the subgroups of patients undergoing glosssectomy, most of the studied parameters did not have statistically significant differences in values. However, it should be noted that in group 2b, the period from the date of surgical treatment to the beginning of rehabilitation was significantly longer than in group 1b.

Conclusion. The use of the microvascular surgical techniques using various donor flaps creates the basis for a more complete functional recovery and expands the rehabilitation potential of patients after surgical treatment of oral and oropharyngeal cancer.
Current treatment strategy for resectable scalp and neck melanoma
Authors: Polyakov A. P. , Rebrikova I. V. , Mordovskiy A. V.
Published: August 2021

Melanoma is a malignant skin tumor associated with a poor clinical prognosis. The incidence of melanoma is constantly rising. Several studies demonstrated that overall and relapse-free survival rates in patients with head and neck melanoma were lower than those in patients with skin melanoma of other locations. Some authors showed that patients with scalp melanoma had the worst prognosis.

Surgery is currently the main treatment option for resectable skin melanoma. It has a number of specific characteristics, such as the need for a smaller resection margin at primary tumor removal in some cases, lower accuracy of sentinel lymph node identification due to the complexity of lymph flow from the scalp and neck, and changes in the standard volumes of lymphadenectomy considering lymph flow from the scalp and neck. Oncologists should have reconstructive surgery skills, because their aim is not only to ensure complete tumor excision, but also to achieve a satisfactory appearance of the patient, especially if the tumor is located in the face, open areas of the head and neck and ears, since this is of functional and aesthetic importance. The administration of adjuvant therapy still causes some controversy in cases where both radiation therapy and pharmacotherapy are indicated.

In this article, we describe the main characteristics of the current treatment strategy for resectable scalp and neck melanoma and cover the main problems in this area that have not been addressed so far.
Subcutaneous emphysema and pneumomediastinum after endoscopic transnasal removal of nasopharyngeal angiofibroma
Authors: Kuznetsov M. S. , Voronov A. V. , Dvoryanchikov V. V. , Svistov D. V. , Nikitin A. I.
Published: August 2021

Introduction. Juvenile nasopharyngeal angiofibroma is a rare, benign, well-vascularized tumor of the skull base characterized by destructive growth. The development of endoscopic techniques and experience of surgeons have enabled the removal of this tumor both at early stages and late stages (advanced disease). Patients may develop various complications in the intraoperative and postoperative periods, including massive bleeding, nasal liquorrhea, facial paresthesia, lacrimal hyposecretion, etc. Air penetration into the subcutaneous fat and mediastinum during endoscopic surgery on the paranasal sinuses is rare. Such complication as subcutaneous emphysema and pneumomediastinum after endoscopic endonasal removal of juvenile nasopharyngeal angiofibroma has not been reported in the literature.

Case report. A 19-year-old male patient has undergone endoscopic endonasal removal of juvenile nasopharyngeal angiofibroma. The tamponade was removed within the first 24 h postoperatively. Ten hours after it, the patient developed subcutaneous emphysema and pneumomediastinum triggered by sneezing. The diagnosis was confirmed by computed tomography of the neck and chest. The patient was transferred to the intensive care unit and received conservative treatment (including infusion, antibacterial, and antiinflammatory therapy). The symptoms of subcutaneous emphysema and pneumomediastinum subsided in response to treatment. Follow-up examinations (computed tomography and magnetic resonance imaging) confirmed that the tumor had been completely removed. The patient was discharged in a satisfactory condition.

Conclusion. Subcutaneous emphysema and pneumomediastinum are exceedingly rare complications of endoscopic endonasal removal of juvenile nasopharyngeal angiofibroma and are caused by anatomical connection between the parapharyngeal / retropharyngeal spaces and mediastinum. To prevent such complications, it is necessary to keep tampons in the nasal cavity for at least 2 days, as well as to instruct patients after surgery (avoid sneezing with their mouth closed, lifting weights, coughing, and vomiting). The nasoseptal flap used to repair the nasopharyngeal defect after tumor removal also ensures its sealing. Patients with complications should undergo computed tomography of the neck and chest (in case of emergency) and should be transferred to an intensive care unit. Conservative treatment (antibacterial and antiinflammatory therapy) will ensure good results in most patients.
Thyroid carcinoma with thymus-like differentiation (CASTLE) tumor: а сase report
Authors: Ilyin A. A. , Polkin V. V. , Isaev P. A. , Sevrukov F. E. , Dvinskych N. Yu. , Ryzhenkova M. I. , Ivanov S. A. , Kaprin A. D.
Published: August 2021

Thyroid carcinoma with thymus-like differentiation (Carcinoma Showing Thymus-Like Differentiation, CASTLE) is an extremely rare disease. It arises from the thymus tissue ectopic into the tissue of the thyroid gland, usually in patients 40–50 years old. In this work, we present an observation of the development of CASTLE in a patient at a young age. A 21-year-old woman was admitted to our clinic with a volumetric education in the projection of the left lobe of the thyroid gland. Ultrasound revealed a 5-centimeter thyroid tumor. Surgery was performed in the scope of thyroidectomy, selective cervical dissection (level VI). Morphological and immunohistochemical studies showed that cancer has a thymus-like differentiation (CASTLE). After 32 months, she recurred to the lymph nodes of the neck (level IV on the left). She underwent repeated surgery, after which she was observed without signs of relapse for 120 months. The rarity of the pathology leads to difficulties in establishing a diagnosis at the preoperative stage and in choosing the optimal treatment tactics during treatment and further follow-up.
Molecular and clinical aspects of oropharyngeal squamous cell carcinoma associated with human papillomavirus
Authors: Polatova D. Sh. , Madaminov A. Yu.
Published: August 2021

Currently, the role of human papillomavirus (HPV) in carcinogenesis is well known: more than 90 % of HPV-positive oropharyngeal squamous cell carcinomas are caused by HPV type 16 (HPV-16). HPV E6 and E7 oncoproteins play a significant role in the development of this tumor. The E6- mediated degradation of suppressor protein p53 results in G2/M-phase checkpoint dysregulation and inhibition of apoptosis. HPV oncoprotein E7 binds to pRb, promoting its degradation and the release of E2F transcription factor. Diagnostic assays for HPV detection include immunohistochemical staining for p16, polymerase chain reaction, in situ hybridization, and next-generation sequencing. Immunohistochemical examination (determination of p16 protein expression) is an economical and very specific way to detect a viral infection. Patients with HPV-positive oropharyngeal squamous cell carcinoma demonstrate significantly better response to treatment and overall survival rates than those with HPV-negative oropharyngeal squamous cell carcinoma. Despite the fact that five-year overall survival rate in patients with HPV-positive oropharyngeal squamous cell carcinoma after treatment exceeds 80 %, some patients have poor survival. Unfortunately, currently available methods of risk stratification still do not endure their timely identification. Further research is needed to address these problems.
Automatic Detection of the Topics in Customer Complaints with Artificial Intelligence
Authors: İLHAN OMURCA Sevinç , EKİNCİ Ekin , YAKUPOĞLU Enes , ARSLAN Emirhan , ÇAPAR Berkay
Published: August 2021

Today, people first make their complaints and compliments on internet about a product which they use or a company they are a customer of. Therefore, when they are going to buy a new product, they first analyze the complaints made by other users of the product. These complaints play an important role in helping people make decision of purchasing or not purchasing product. It is impossible to analyze online complaints manually due to the huge data size. However, companies are still losing a lot of time by analyzing and reading thousands of complaints one by one. In this article, online text based customer complaints are analyzed with Latent Dirichlet Allocation (LDA), GenSim LDA, Mallet LDA and Gibbs Sampling for Dirichlet Multinomial Mixture model (GSDMM) and the performances of them are compared. It is observed that GSDMM gives much more successful results than LDA. The obtained topics of the complaints are presented to users with a mobile application developed in React Native. With the developed application not only the customers will be able to see the topics of complaint from the application interface but also the companies will be able to view the distribution and statistics of the topics of complaints.
Real-Time Hand Motion Recognition: A Robust Low-Cost Approach
Authors: BAS Anil , KOCER H. Erdinç
Published: August 2021

This study presents a robust, low-cost hand motion recognition approach designed to run on low-end computer systems. Our method detects and tracks hand region using real-time images obtained from a low-resolution camera (i.e. webcam) and is not depended on any training or calibration and is not required any special camera apparatus or selectors. The proposed system involves several image processing techniques such as background subtraction, face detection, skin colour detection and template matching. The experimental results show promising performance under various conditions. The method has a wide range of applications where more natural ways of interaction required, such as virtual reality applications, assistive technologies and simulation.
Analysis of a Compact Multi-Band Textile Antenna for WBAN and WLAN Applications
Authors: SAVCI Hüseyin , SAJJAD Hassan , KHAN Sana , KABURCUK Fatih
Published: August 2021

A dual-band wearable antenna is designed on a textile material. The design operates at ISM bands available for Wireless Body Area Network and Wireless Local Area Network with an input match better than -15 dB. The antenna is designed by using Computational Electromagnetic Software (CEMS) based on finite-difference time-domain (FDTD) method. A three-layer phantom model including skin, fat and muscle has been considered to compute the specific absorption rate (SAR). The maximum value of SAR averaged over 1g and 10g of tissue is less than 1.6 W/Kg and 2 W/Kg, respectively, when the maximum incident power of the antenna is 63 mW. These values are incompliance with the international electromagnetic safety standards.
An Approach Based on Tunicate Swarm Algorithm to Solve Partitional Clustering Problem
Authors: ASLAN Murat
Published: August 2021

The tunicate swarm algorithm (TSA) is a newly proposed population-based swarm optimizer for solving global optimization problems. TSA uses best solution in the population in order improve the intensification and diversification of the tunicates. Thus, the possibility of finding a better position for search agents has increased. The aim of the clustering algorithms is to distributed the data instances into some groups according to similar and dissimilar features of instances. Therefore, with a proper clustering algorithm the dataset will be separated to some groups with minimum similarities. In this work, firstly, an approach based on TSA algorithm has proposed for solving partitional clustering problem. Then, the TSA algorithm is implemented on ten different clustering problems taken from UCI Machine Learning Repository, and the clustering performance of the TSA is compared with the performances of the three well known clustering algorithms such as fuzzy c-means, k-means and k-medoids. The experimental results and comparisons show that the TSA based approach is highly competitive and robust optimizer for solving the partitional clustering problems.
Comparisons of Different Maximum Power Point Tracking Strategies with Zeta Converter
Authors: BAŞOĞLU Mustafa Engin
Published: August 2021

Maximum power point tracking (MPPT) strategy is one of the major parameters affecting efficiency in photovoltaic (PV) systems. In this paper, distributed MPPT approaches are compared with central mode MPPT. Advantages and disadvantages of submodule level MPPT technique and module level MPPT approach are shown with simulation studies. Comparisons are made with incremental conductance (IC) algorithm. In this context, non-isolated zeta converter is used as a power processing unit. Effect of the MPPT strategy on the collected energy performance is observed by simulation studies performed in MATLAB/Simulink. It is clear by these studies that energy capture is bigger in submodule level MPPT strategy and module level MPPT with respect to central mode which is seen by simulations. However, central mode MPPT offers cost effective solution because of the low hardware requirements.
A Hybrid Machine Learning Model to Detect Reflected XSS Attack
Authors: BUZ Beraat , GÜLÇİÇEK Berke , BAHTİYAR Şerif
Published: August 2021

Since web technologies are getting more advanced with longer codes, the number of vulnerabilities has increased considerably. Cross-site scripting (XSS) attacks are one of the most common attacks that use vulnerabilities in web applications. There are three types of cross-site scripting attacks namely, reflected, stored, and DOM-based attacks. Reflected XSS attacks are the most common type that is usually implemented by injecting a malicious code into the URL and then sending the URL to the targeted system by using phishing methods, which is a significant threat for recent web applications. Our motivation is the lack of a high performance detection method of reflected XSS attacks with high accuracy. In this paper, we propose a hybrid machine learning model to detect vulnerabilities related to reflected XSS attacks for a given URL of a website. Our model uses a scanner to discover vulnerabilities in a web site and convolutional neural networks to predict the most common vulnerabilities that may be used for reflected XSS attacks, which makes the proposed model hybrid. We analyzed the model experimentally. Analyses results show that the proposed model is able to detect vulnerable attack surfaces with 99 % accuracy.
Development of an Embedded System for Building System Management Based on PV-Powered
Authors: ALİ Hussein , ERÇELEBİ Ergün
Published: August 2021

As complexity and the type of electrical applications perpetually expands, monitor and control will require new systems which are based on some features in such feature of self-powered and distantly management. Building management systems (BMSs) are developed as efficient solutions to monitor and control users electrical and mechanical applications. A BMS employs cheap sensors and a real-time module to create prior knowledge about the climate inside the building. As a result, these features give some attractive advantages in taking a precise decision and managing vital operations of electrical applications. In this paper, a Raspberry Pi as minicomputer for collecting information from server room or data centre for detection the existence of human, temperature and humidity sensor and gas sensors to control ventilation systems, Arduino platform is responsible for receiving sensors signal and control actions according to the statues in the server room. While the Xbee protocol has been used to transmit data from the sensing node (Raspberry PI3) to mentors and control nodes (Arduino mega2560). The prototype design has been verified experimentally.
Risk factors for developing epilepsy in children with cerebral pals
Authors: Mammadbayli A K , Taghiyeva M R
Published: August 2021

Aim. To identify the most important risk factors affecting the development of epilepsy in children with cerebral palsy.

Methods. The study included 160 cerebral palsy patients with and without epilepsy who received treatment at the Baku Children's Neurological Hospital. The patients were divided into 2 groups. The first group consisted of 110 (68.7%) patients with cerebral palsy and epilepsy, and the second group consisted of 50 (31.3%) patients with cerebral palsy. The age of children ranged from 1 to 14 years. Statistical data processing was performed by using the SPSS software version 16.0. The Chi-square test was used to compare categorical measurements. T-test for independent groups was used for comparison between groups of continuous measurements. Binary logistic regression was used for determining the risk factors. In all tests, the level of statistical significance was set at p 0.05.

Results. There was no significant difference in age and gender distribution between groups (p=0.492 and p=0.818, respectively). 10 (9.1%) children in the main group had a positive family history of epilepsy (odds ratio 8.08, p=0.028). Neonatal seizures were observed in 25 (22.7%) children in the main group and 3 (6%) children in the control group (odds ratio 4.4, p=0.010). The presence of infection during pregnancy in the mother was found in both the main (39.1%) and control (20%) groups (odds ratio 2.6, p=0.018). Level IV of the Gross Motor Function Classification System (GMFCS) was the most frequent among patients with epilepsy (odds ratio 12.8; p=0.035). The incidence rate of epilepsy among cerebral palsy patients was 68.7%. The mean age of onset of seizures was 19.226.6 months. The most frequent epileptic seizures (55.5%) occurred in spastic quadriplegic cerebral palsy.

Conclusion. The presence of a positive family history of epilepsy, neonatal seizures, maternal infection during pregnancy and severe GMFCS level were identified as factors for the development of epilepsy in patients with cerebral palsy; premature birth, presence of hypoxic-ischemic injury, low birth weight, consanguineous marriage, multiple pregnancies, or gender were not identified as risk factors for the development of epilepsy in children.
Perioperative antibiotic prophylaxis for abdominal delivery at the regional perinatal center
Authors: Tashtanbekova Ch B , Evstratov A A , Chuenkova E A , Ziganshina L E
Published: August 2021

Aim. To conduct a comparative pharmacoepidemiological study and assess the rational use of antibiotics in women undergoing caesarean section.

Methods. A retrospective analysis of 1,025 birth histories of women after planned and emergency cesarean section was carried out with a detailed assessment of the use of antibiotics in 20072009 (523) and 20162017 (502) with an interval of 10 years for which new clinical guidelines, principles of rational pharmacotherapy and evidence-based medicine were introduced. The time of administration of the first dose, duration of administration, consumption of antibiotics were assessed. The significance of differences in relative indicators was assessed according to Pearson (2).

Results. Antibiotics were prescribed to women with planned and emergency caesarean section in 100% of cases in the first period of the study (20072009) and prescribed in 98% of women with planned caesarean section and 96% with emergency caesarean section in the second period (20162017). In the first period, the first dose of antibiotic was administered: in 110 (44%) cases during surgery and 139 (56%) cases after surgery in planned caesarean section; in 139 (51%) cases during surgery and 135 (49%) cases after surgery in emergency caesarean section. In the second period, antibiotics were administered 3060 minutes before the operation in 263 (96%) cases in the planned caesarean section and 218 (95%) cases in the emergency; postoperative antibiotics were administered in 7 (2%) women in the planned caesarean section and 2 (1%) women in the emergency (p 0.05). Greater than 56 days of antibiotics were used: in 166 (67%) women in the planned operation and 166 (61%) in the emergency for the first period; in 43 (16%) women with the planned operation, and 38 (17%, p 0.05) women with an emergency for the second period. In the first period, 13 antibiotics from 8 pharmacotherapeutic groups were used and in the second period, 7 out of 5 were used.

Conclusion. From 2007 to 2017, the use of antibiotics has become to comply with the implemented clinical guidelines for abdominal delivery: the duration of antibiotic use has decreased, the time of administration of the first dose and the range of antibiotics used changed.
Analysis of antithrombotic therapy in elderly patients with nonvalvular atrial fibrillation in the Kyrgyz Republic and ways to increase treatment adherencе
Authors: Kinderbaeva N K , Bazira K , Karabekova N M , Mamatova R M , Asel Zh , Nartaeva A K , Mamatov S M
Published: August 2021

Aim. To analyze anticoagulant therapy in elderly patients with non-valvular atrial fibrillation and ways to increase adherence in the work of a specialized team.

Methods. The study followed 250 patients with non-valvular atrial fibrillation aged 65 to 74 years (mean age 70.74.39 years). The patients were divided into three groups: the first group included 105 people, who were prescribed warfarin in a retrospective study; the second group 57 people treated with rivaroxaban, and the third group 88 people treated with warfarin. The second and third groups were prospective study groups which were supervised by a specialized team of physicians. The groups were matched on sex and age, comorbidities. Statistical data analysis and mathematical processing were performed by using the methods of descriptive and variational statistics. Most parameters reported as absolute values and percentages, while quantitative data the 25th and 75th percentiles.

Results. All patients included in the study had a high risk of developing thromboembolic complications by their CHA2DS2-VASc score (2) and a low risk of developing hemorrhagic complications on the HAS-BLED scale (average score 1.490.04). They were prescribed anticoagulant therapy. By the end of the year follow-up from the start of anticoagulant therapy, only 9.5% of patients were treatment adherent, in the second group 43.8%, in the third group 70.5% of patients. The reason for refusing to take warfarin in the vast majority of cases was the inability to control the international normalized ratio, medical contraindications, and the high cost of the drug in prescribing rivaroxaban. The results showed that the majority of patients with atrial fibrillation (90.5%) receive inadequate antithrombotic therapy in routine outpatient clinical practice. At the same time, in a very small number of patients (9.5%) receiving warfarin, this type of therapy can be considered adequate (60% or more of the stay time in the therapeutic range of international normalized ratio of 2.0 to 3.0).

Conclusion. Anticoagulant therapy prescription under the supervision of a specialized team contributes to a significant improvement in treatment adherence (from 43.8 to 70.5%); promising in the future is the use of drugs from the group of new oral anticoagulants that do not require routine monitoring of coagulogram.
Systemic inflammation and nutritional insufficiency in palliative cancer patients
Authors: Kurchenkova O V , Kharlamova U V , Vazhenin A V , Abdalov A O
Published: August 2021

Aim. To study the relationship between the symptoms of nutritional insufficiency and systemic inflammation in cancer palliative patients.
Methods. 106 palliative cancer patients were examined at Chelyabinsk Regional Clinical Center of Oncology and Nuclear Medicine: 54 (50.9%) men and 52 (49.1%) women aged 61 [54; 67] years. All patients underwent laboratory and instrumental examination within the approved standards of specialized medical care. Systemic inflammation was assessed by the levels of acute phase proteins (C-reactive protein, fibrinogen). The study of integrated clinical and laboratory, somatometric parameters was carried out. The nutritional risk index was assessed.
Results. Palliative cancer patients showed a statistically significant decrease in the concentration of hemoglobin, lymphocytes, and albumin. The activation of systemic inflammation that manifested by hyperfibrinogenemia and an increase in the level of C-reactive protein was revealed. The study of somatometric parameters revealed a statistically significant decrease in body mass index, shoulder circumference, subscapular skinfold thickness, and a tendency to reduce lean body mass. The nutritional risk index assessment showed mild nutritional insufficiency in 22 (20.8%) of the examined patients and severe nutritional insufficiency in 28 (26.4%) patients. The maximum diagnostic significance of the level of C-reactive protein for prediction the nutritional insufficiency was achieved at 80.4% sensitivity and 52.7% specificity (AUC=0.671, 95% confidence interval [0.573; 0.759], p=0.001), which corresponded to a C-reactive protein threshold of 31 mg/l.
Conclusion. 50 (47.2%) of the examined patients showed signs of nutritional insufficiency, a statistically significant decrease in hemoglobin and albumin concentration, as well as lymphocyte count, activation of systemic inflammation, manifested by hyperfibrinogenemia, and an increase in the level of C-reactive protein; it was revealed a statistically significant relationship between C-reactive protein level and malnutrition.
Improving the Russian-language Wikipedia articles on medicines using new knowledge Cochrane
Authors: Potapov A S , Alexandrova E G , Yudina E V , Ziganshina L E
Published: August 2021

Aim. To evaluate the effectiveness of the Cochrane Russia Initiative to improve the articles of the Russian-language Wikipedia by including information from Cochrane Systematic Reviews (CSR) to ensure the accuracy and impartiality of their content as an information basis for the quality use of medicines by doctors and the public.

Methods. Wikipedia articles on selected drugs were improved by introducing evidence from Cochrane Systematic Reviews Cochrenized. A parallel open-label non-randomized controlled intervention study was conducted. We assigned 2 groups of drugs and Wikipedia articles about them: the intervention group (Cochrenization) and the control group (36 articles each). Control group articles were not edited. The change in the number of visits to Wikipedia pages for the year (20182019) was measured, the statistical significance of the differences was assessed by using the Wilcoxon signed-rank test.

Results. We edited 36 Wikipedia articles, including 13 articles on migraine treatment, 9 diabetes mellitus, 14 pain and inflammation articles. These articles constituted the intervention group. The control group consisted of articles on cardiovascular (11), gastrointestinal (14) and dermatological agents (11). We used the Cochrane Russia Initiative dashboard on Wikipedia to compare the number of article views before and after the intervention and Cochrane analytics on demand for translations of Cochrane systematic reviews summaries. After Cochrenization, the number of Wikipedia article views (20182019) increased in total/average article views for treatments: migraines by 18%/47%, pain and inflammation 16%/43%, diabetes mellitus 18%/0%. Analysis of Cochrane reports showed an increase in the number of views of Cochrane systematic reviews summaries on the Cochrane.org website in general by 9 times and from Russian-speaking browsers by 11 times. Improvement of medicine-related articles of the Russian-language Wikipedia by the introduction of information from Cochrane systematic reviews was accompanied by an increase in their demand in terms of the number of views in general by 34%, with a similar increase in control (without intervention) (p-value of the experimental group 0.002, control 0.000). The Wikipedia articles on medicines, which belonged to the Russian Vital and Essential Drugs List or the World Health Organization Model List of Essential Medicines, got more views.

Conclusion. The role of confounding factors justifies the feasibility of developing a methodology for studying the usefulness of improving Wikipedia articles, different from controlled trial research methodology; further inclusion of Cochrane knowledge into Wikipedia is needed.
Analysis of microcirculatory disorders in men with more than 10 years’ experience on night work
Authors: Gribanov I A , Zarubina E G
Published: August 2021

Aim. To study the nature and extent of the effects of long-term sleep and wake phase disorders (working at night for more than 10 years) on the characteristics of microcirculation in men.

Methods. Laser Doppler flowmetry and spectophotometry, optical tissue oximetry, and laser-induced fluorescence spectroscopy were performed in 34 male patients with a mean age of 40.30.9 years and more than 10 years experience of night work to assess the effectiveness of microcirculation. 25 men with a mean age of 40.21.2 without night work experience were used as a control group. Microcirculation was studied on the laser diagnostic complex LAKK-M (LAZMA, Russian Federation). The measurement was carried out on the skin of the palmar surface of the terminal phalanx of the second finger of the hand. The following indicators were analyzed in automatic mode: the mean perfusion value, the index of specific oxygen consumption in the tissue, capillary blood saturation, the relative volume of the red blood cell fraction, arterial blood oxygen saturation, the index of perfusion oxygen saturation in the microcirculation, the efficiency of oxygen exchange and the fluorescent indicator of oxygen consumption. Statistical processing of the results was carried out using the Student's t-test for independent samples.

Results. In patients working at night for more than 10 years, a decrease in microcirculation efficiency was revealed. The index of specific oxygen consumption in the tissue was lower than that of healthy volunteers by 34.1% (p=0.000255), and the index of oxygen exchange efficiency by 56.3% (p 0.001). Long-term night work (10 years) can lead to violations of microcirculation parameters and an irreversible decrease in the efficiency of oxygen exchange compared with the control group by an average of 56.3% (18.00.5 for the group with night work experience, 41.20.6 for the group of healthy volunteers, p 0.001), the index of specific oxygen consumption in the tissue by an average of 34.1% (1.530.03 for the group with night work experience, 2.320.2 for the group of healthy volunteers, p=0.000255) and an increase in the index of perfusion oxygen saturation in the microcirculation by 2 times compared with the control group (6.20.05 for the group with night work experience, 3.670.09 for the group of healthy volunteers, p 0.001), which is accompanied by an increase in the saturation of mixed (and venous) blood.

Conclusion. The nature of the revealed violations of microcirculatory parameters in the long-term night work suggests their significance in the development of diseases that are currently attributable to the so-called group of diseases of civilization.