bluuebunny/crossref_metadata_2025 huggingface dataset:
Understanding Self-Care Behaviours among Type II Diabetes Patients:
A Behaviour Change Models’ Perspective
Authors: Rajkumar Eslavath , Lakshmi R. , Kruthika G.T. , Padiri Ruth Angiel , Daniel Monica , John Romate , Abraham John
Published: May 2022

Background:

Self-care behaviours among diabetes patients is often hindered because of
various psycho-social factors which become obstacles to their better diabetes management and its
proper outcome. The current study aims to find out these psycho-social factors that influence the
execution of self–care behaviours among Type II diabetes patients from the perspective of various
behaviour change models.

Methods:

The study adopted a correlational research design. A total of 266 participants above the
age group of 18 years and diagnosed with type 2 diabetes were selected using purposive sampling
from the Indian state of Karnataka. The data were collected using The Health Belief Questionnaire,
Theory of Planned Behaviour Questionnaire (TPBQ), Socio-Ecological Model Questionnaire, and
Diabetic Self-Care Activities Revised (SDSCA-R). The data were analysed using descriptive statistics,
Pearson product-moment correlation and multiple regression.

Results:

From the findings, it was observed that the domains of perceived susceptibility, cues to
action and subjective norms are positively correlated with self-care behaviours significantly at
p<0.05 levels, while the domains of socio-ecological theory, personal, interpersonal, media and
policy and community organizations are significantly positively correlated with self-care behaviour
at p<0.01 levels. The linear regression of the domains of health belief model, theory of planned
behaviour and socio-ecological theory on self-care behaviour showed that the statistically significant
final model explained 14.9% (R2 =.149), F (3,262) =15.337, p< 0.000. The significant predictors
are community at p<0.000 level, self-efficacy and perceived severity at p<0.05 levels.

Conclusion:

The study results ascertain the necessity of a psychosocial approach or the sociocognitive
perspective to understand the factors that actually enable a diabetes patient to engage in
more self-care behaviours. In the Indian scenario, where health literacy is very minimum, the findings
of the study can be used to implement better strategies for diabetes management both at the
level of medical/mental health professionals and at the level of media and policy.
Advancement in Understanding the Concept of Epithelial to Mesenchymal
Transition in Pancreatic β-Cells: Implication in Diabetes
Authors: Francis Meenal , Ashok Akshaya , Ashwathnarayan Ashwini , Banerjee Shreetama , Prasanna Jyothi , Kumar Anujith
Published: May 2022

Distinct molecular processes are engaged during histogenesis, and Epithelial to Mesenchymal
Transition (EMT) is one of the key evolutionarily conserved processes that facilitates organ
development. Molecular pathways governing EMT are embedded within developmental programs
and operate in cells of different tissues. Among varied cell types, EMT in pancreatic β-cells is of
greater interest as the existence of EMT in these cells is highly debated. Although in vitro generation
of human islet-derived mesenchymal progenitor cells has been proven beyond doubt, the existence
of EMT in pancreatic β-cells in vivo remains enigmatic. Understanding the in-depth process of
EMT in in vivo human β-cells is challenged by the limitations of lineage-tracing studies, which are
otherwise feasible in mice. Exploring EMT of β-cells would greatly facilitate the generation of clinically
relevant β-cells either by enhancing long-term in vitro culture of endogenous islets or by differentiation
of pluripotent stem cells to mature β-cells. This review is an update on the recent progress
in understanding the EMT process of β-cells and how the investigations have helped to resolve
the mystery of the existence of EMT in pancreatic β-cells.
Hyperspectral Imaging: A Review and Trends towards Medical Imaging
Authors: Karim Shahid , Qadir Akeel , Farooq Umar , Shakir Muhammad , Laghari Asif Ali
Published: May 2022

Hyperspectral Imaging (HSI) is a pertinent technique to provide meaningful information about unique objects in the medical field. In this paper, the basic principles, imaging methods, comparisons, and current advances in the medical applications of HSI are discussed to accentuate the importance of HSI in the medical field. To date, there are numerous tools and methods to fix the problems, but reliable medical HSI tools and methods need to be studied. The enactment and analytical competencies of HSI for medical imaging are discussed. Specifically, the recent successes and limitations of HSI in biomedical are presented to offer the readers an insight into its current potential for medical research. Lastly, we have discussed the future challenges concerning medical applications and possible ways to overcome these limitations.
WITHDRAWN: Non-Destructive Method for the Determination of Amikacin
in Amikacin Sulphate Injection Using ATR-FTIR Spectroscopy with
PLS Regression
Authors: Akowuah Gabriel A. , Chow Jie C. , Yi Yau X. , Lokesh Bontha V.S
Published: May 2022

The article has been withdrawn at the request of the author of the journal Current Analytical Chemistry.

Bentham Science apologizes to the readers of the journal for any inconvenience this may have caused.

The Bentham Editorial Policy on Article Withdrawal can be found at https://benthamscience.com/editorial-policies-main.php

Bentham Science Disclaimer:

It is a condition of publication that manuscripts submitted to this journal have not been published and will not be simultaneously
submitted or published elsewhere. Furthermore, any data, illustration, structure or table that has been published elsewhere
must be reported, and copyright permission for reproduction must be obtained. Plagiarism is strictly forbidden, and by submitting
the article for publication the authors agree that the publishers have the legal right to take appropriate action against the
authors, if plagiarism or fabricated information is discovered. By submitting a manuscript, the authors agree that the copyright
of their article is transferred to the publishers if and when the article is accepted for publication.
ZFP36L1 Promotes Gastric Cancer Progression via Regulating JNK and
p38 MAPK Signaling Pathways
Authors: Ding Kang , Zhang Fengping , Qi Gaoxiu , Lin Meng , Chen Min , Chen Yanchun , Zheng Jie , Zhou Fenghua
Published: May 2022

Background:

The RNA-binding protein Zinc Finger Protein 36 like 1(ZFP36L1) plays an important role in regulating the AU-rich elements (AREs) in the 3′ untranslated region (3′ UTR) of mRNAs, indicating a potential link between its expression and cancers. However, the role and mechanism of ZFP36L1 in gastric cancer (GC) are unclear.

Objective:

This study aimed to explore the role and mechanism of ZFP36L1 in gastric cancer.

Material and Method:

GC tissue samples and matched normal gastric tissues were collected, and the ZFP36L1 expression in these samples was evaluated by immunohistochemistry analysis. GC cells with different differentiation were selected for in vitro experiments. The ZFP36L1 expression in GC cells was examined by quantitative real-time polymerase chain reaction (qRT-PCR) and Western blot analysis. The viability and invasiveness of GC cells were assayed by 5-Ethynyl-2-deoxyuridine (EdU) and Transwell assays, respectively. Western blot assay was used to detect the expression of epithelial-to-mesenchymal transition (EMT) related proteins and proteins of the c-Jun N-terminal kinase (JNK) and p38 Mitogen-Activated Protein Kinase (MAPK) signaling pathways.

Results:

ZFP36L1 is overexpressed in GC tissues. Patients with high ZFP36L1 expression have a poor prognosis. Moreover, ZFP36L1 is overexpressed in the cell lines with a high degree of malig-nancy. ZFP36L1 increases cell proliferation, invasion, and migration in vitro. Furthermore, ZFP36L1 induces EMT. The JNK inhibitor and p38 inhibitor alone or in combination affect the biological function of GC cells. Furthermore, ZFP36L1 promotes GC progression by inhibiting JNK and p38 MAPK signaling pathways.

Conclusion:

RNA-binding protein ZFP36L1 exerts a role in the occurrence of gastric cancer by the regulation of the JNK and p38 MAPK signaling pathways. The combination of inhibitors of the JNK and p38 MAPK signaling pathways could be a novel treatment strategy for gastric cancer.
GenNBPSeq: Online Web Server to Generate Never Born Protein
Sequences Using Toeplitz Matrix Approach with Structure Analysis
Authors: Karuna Nidhi Muthugobal Bagayalakshmi , Ganapathy Ramesh , Subbiah Parthasarathy , Suvaiyarasan Suvaithenamudhan , Karuppasamy Muthuvel Prasath
Published: May 2022

Background:

In biology, the translation of genetic information to its corresponding protein sequences is carried out by using the Universal Genetic Code. Out of all the possible combinations of 20 amino acids, proteins are formed by the possible combinations that occur naturally. This leaves a large number of unknown combinations of protein sequences that includes the Never Born Proteins. A Never Born Protein is a theoretically possible protein that does not occur in nature or may be selected by evolution in future.

Objective:

In this study, the "GenNBPSeq" online web server is developed to generate Never Born Protein Sequences and to analyze their sequence and structural stability.

Methods:

The “GenNBPSeq” server is developed based on the Gray Code and Partitioned Gray Code representations of the Universal Genetic Code combined with the novel Toeplitz matrix approach. The sequence and structure analysis is done by various Bioinformatics tools for the sample Never Born Protein sequences.

Results:

The “GenNBPSeq” server is available at http://bioinfo.bdu.ac.in/nbps and the users can generate Never Born Protein sequences and download them in FASTA formats. The Never Born Protein sequences obtained by the above Toeplitz matrix approach contain same amino acid composition. They also form protein secondary and 3-Dimensional structures with intrinsic stability.

Conclusion:

This study conjectures that the Never Born Protein Sequences generated by “GenNBPSeq” server using Toeplitz matrix approach may exhibit intrinsic structural stability. Synthesizing these Never Born Proteins and analyzing their biological applications are major research areas in Systems and Synthetic Biology.
Molecular Mechanisms of Chloroquine and Hydroxychloroquine Used in Cancer Therapy
Authors: De Sanctis Juan Bautista , Charris Jaime , Blanco Zuleyma , Ramírez Hegira , Martínez Gricelis Patricia , Mijares Michael Rodney
Published: May 2022

Tumour relapse, chemotherapy resistance, and metastasis continue to be unsolved issues in cancer therapy. A recent approach has been to scrutinise drugs used in the clinic for other illnesses and modify their structure to increase selectivity to cancer cells. Chloroquine (CQ) and hydroxychloroquine (HCQ), known antimalarials, have successfully treated autoimmune and neoplastic diseases. CQ and HCQ, well-known lysosomotropic agents, induce apoptosis, downregulate autophagy, and modify the tumour microenvironment. Moreover, they affect the Toll 9/NF-κB receptor pathway, activate stress response pathways, enhance p53 activity and CXCR4-CXCL12 expression in cancer cells, which would help explain their effects in cancer treatment. These compounds can normalise the tumourassociated vasculature, promote the activation of the immune system, change the phenotype of tumour-associated macrophages (from M2 to M1), and stimulate cancer-associated fibroblasts. We aim to review the historical aspects of CQ and its derivatives and the most relevant mechanisms that support the therapeutic use of CQ and HCQ for the treatment of cancer.
Behind the theoretical debate between Hans Kelsen and Carl Schmitt: the nineteenth century constitutionalism and German public law
Authors: Scholz-Karl Julia
Published: May 2022

This paper aims at identifying the reminiscences of 19th century constitutionalism and German public law behind the theoretical discussion around the constitutional jurisdiction in the doctrines of Hans Kelsen and Carl Schmitt. The doctrines on the question of sovereignty and constitution between the 19th and early 20th centuries also become the object of study as they reflect on the theoretical debate between Hans Kelsen's Neokantian positivism and Carl Schmitt's decisionism. Finally, from the notions of separation of powers, sovereignty, and constitution provided by these authors, the research aims at identifying the theoretical lines and concepts that may have contributed to the construction of the notion of guardian of the constitution. As a  result, it was possible to verify that while Schmitt's constitutional theory carries much of his "political theology" with it, Kelsen sought, with his Pure Theory of Law, to evade from the theological method present in other legal theories (especially in Schmitt's). His intention was to build a legal science free of strange elements to Law, such as morality, politics and religion, which reflected in the choice of who should be the guardian of the Constitution. We developed this research through the analysis of historical sources and bibliographical research in the main writings of Carl Schmitt and Hans Kelsen on constitutional theory. As historiography, we sought specialized literature on the main subjects and theorists researched, from great names from that time and by contemporary well-known authors.
A review of International Counter-Terrorism strategy through a criminological assessment of the punitive model implemented in Europe
Authors: Ropero Carrasco Julia , García Sánchez Beatriz
Published: May 2022

Jihadist terrorism, especially since the Al-Qaeda attacks in 2001 and Daesh’s consolidation as an autonomous group in the following decade, have been a major global political concern. In turn, the cruelty exhibited by the Daesh has had an undeniable impact on public opinion, which demands security above all else and has been exploited by the public authorities to promote military and security strategies, along with a restrictive policy on fundamental rights such as freedom of expression, pushing the criminal barrier to questionable limits. The objective of this article is to offer a critical vision of these policies, based on empirical data, about the phenomenon of foreign terrorist combatants.
Legal pluralism, indigenous rights and the Inter-American corpus iuris
Authors: Borges Bruno Barbosa
Published: May 2022

The permeability between state, regional and universal legal systems for the protection of human rights is increasingly evident, materialising a trend of legal pluralism in a multilevel universe of human rights protection. Therefore, it is important to interpret the norms contained in national constitutions and international treaties – that is, the different systems for the protection of human rights – in light of the pro persona principle. In this context, the indigenous issue stands out for its complexity and urgent safeguard, given the past and current scenarios of numerous violations. The indigenous cosmovision must permeate any application of the mechanisms for protecting the human rights of indigenous peoples. In order to better understand this pluralism from the perspective of safeguarding indigenous rights, a brief study was carried out on the constitutionalization of these rights in Latin America and their interpretation in the Inter-American system for the protection of human rights. The question is: what are the main indigenous rights contained in Latin American constitutions? How does the Inter-American system interpret these rights in light of the American Declaration and Convention? What are the protective standards for indigenous rights in the region? For that, the method of approach used was the deductive one and the methodological procedures were in the juridical and systematic dogmatic study. As a result of this research, it was found that there is an entire Inter-American corpus iuris that must be protected, based on the duty of harmonisation imposed by the American Convention, and carried out through the control of conventionality
Understanding the Security and Privacy Concerns About the Use of Identifiable Health Data in the Context of the COVID-19 Pandemic: Survey Study of Public Attitudes Toward COVID-19 and Data-Sharing
Authors: Summers Charlotte , Griffiths Frances , Cave Jonathan , Panesar Arjun
Published: May 2022

Background

The COVID-19 pandemic increased the availability and use of population and individual health data to optimize tracking and analysis of the spread of the virus. Many health care services have had to rapidly digitalize in order to maintain the continuity of care provision. Data collection and dissemination have provided critical support for defending against the spread of the virus since the beginning of the pandemic; however, little is known about public perceptions of and attitudes toward the use, privacy, and security of data.

Objective

The goal of this study is to better understand people’s willingness to share data in the context of the COVID-19 pandemic.

Methods

A web-based survey was conducted on individuals’ use of and attitudes toward health data for individuals aged 18 years and older, and in particular, with a reported diagnosis of a chronic health condition placing them at the highest risk of severe COVID-19.

Results

In total, 4764 individuals responded to this web-based survey, of whom 4674 (98.1%) reported a medical diagnosis of at least 1 health condition (3 per person on average), with type 2 diabetes (n=2974, 62.7%), hypertension (n=2147, 45.2%), and type 1 diabetes (n=1299, 27.4%) being most prominent in our sample. In general, more people are comfortable with sharing anonymized data than personally identifiable data. People reported feeling comfortable sharing data that were able to benefit others; 66% (3121 respondents) would share personal identifiable data if its primary purpose was deemed beneficial for the health of others. Almost two-thirds (n=3026; 63.9%) would consent to sharing personal, sensitive health data with government or health authority organizations. Conversely, over a quarter of respondents (n=1297, 27.8%) stated that they did not trust any organization to protect their data, and 54% (n=2528) of them reported concerns about the implications of sharing personal information. Almost two-thirds (n=3054, 65%) of respondents were concerned about the provisions of appropriate legislation that seeks to prevent data misuse and hold organizations accountable in the case of data misuse.

Conclusions

Although our survey focused mainly on the views of those living with chronic health conditions, the results indicate that data sensitivity is highly contextual. More people are more comfortable with sharing anonymized data rather than personally identifiable data. Willingness to share data also depended on the receiving body, highlighting trust as a key theme, in particular who may have access to shared personal health data and how they may be used in the future. The nascency of legal guidance in this area suggests a need for humanitarian guidelines for data responsibility during disaster relief operations such as pandemics and for involving the public in their development.
Using the PMAQ-AB Mobile App and Management System to Evaluate the Quality of Primary Health Care in Brazil: Qualitative Case Study
Authors: Bay Júnior Osvaldo de Goes , Diniz Vieira Silva Cícera Renata , Santos Martiniano Cláudia , de Figueiredo Melo Lygia Maria , Barros de Souza Marize , Lopes Monique da Silva , Coelho Ardigleusa Alves , de Medeiros Rocha Paulo , de Albuquerque Pinheiro Themis Xavier , de Sá Pinto Dantas Rocha Nadja , da Costa Uchôa Severina Alice
Published: May 2022

Background

The application of cell phones, similar portable devices (ie, tablets), apps, the internet, and GPS in evaluation have established new ways of collecting, storing, retrieving, transmitting, and processing data or information. However, evidence is incipient as to which technological resources remain at the center of assessment practice and the factors that promote their use by the assessment community.

Objective

This study aimed to analyze the relationship between the use of the National Program for Improving Primary Healthcare Access and Quality’s (PMAQ-AB; Programa Nacional de Melhoria do Acesso e da Qualidade da Atenção Básica) mobile app and management system and the external evaluation quality of Brazil’s PMAQ-AB.

Methods

We conducted a qualitative case study during the external evaluation of Brazil’s PMAQ-AB. Data collection consisted of interviews, focus groups, and document analysis. A total of 7 members from the Department of Primary Care of the Ministry of Health and 47 researchers from various higher education and research institutions across the country participated in the study. Data were categorized using the ATLAS.ti software program, according to the quality standards of the Joint Committee on Standards for Educational Evaluation, following the content analysis approach by Bardin.

Results

The results related to feasibility, thematic scope, field activity management, standardized data collection, data consistency, and transparency. They demonstrated improvements and opportunities for advancements in evaluation mediated by the use of information technology (IT), favored the emergence of new practices and remodeling of existing ones, and took into account the multiple components required by the complex assessment of access and quality in primary health care. Difficulties in technology operation, inoperative systems, and lack of investment in equipment and human resources posed challenges to increasing the effectiveness of IT in evaluation.

Conclusions

The use of technology-based tools—the app and the management system—during the external evaluation offered evaluators a greater opportunity for stakeholder engagement. This also allowed the insertion of different organizational, operational, and methodological components that are capable of triggering influences and confluences. In addition, this allowed connections in collaborative and synergistic networks to increase the quality and allow the development of a more consistent and efficient evaluation process with greater possibility of incorporating the results into public health policies.
A Web Platform for Standardized Data Acquisition, Processing, and Export in the Child Psychopathology Clinical Routine (MedicalBIT): Design and Implementation Study
Authors: Colombo Paola , Busti Ceccarelli Silvia , Pacchiarini Stefano , Cribellati Stefano , Molteni Massimo
Published: May 2022

Background

The rapid extent of digital innovation for the collection of data has transformed the way in which health professionals collect, share, and analyze health information for better clinical decision-making and health care. In the last decade, there has been an increased interest in telemedicine by mental health agencies; the gap between the need for care and both diagnosis and treatment is wide, and digital technology could play an important role in filling this gap. However, there are limited data on the effectiveness of the clinical process and cost-effectiveness of most telemedicine applications.

Objective

This study examined the implementation of the first Italian online, web-based, comprehensive screening tool and described the screening and diagnostic process through the interactive web platform in a child psychopathology clinic. This is a feasibility study that aims to present the design and implementation of the best practices to improve patient experiences and clinical outcomes. Moreover, the paper evaluates the platform with qualitative and quantitative measures.

Methods

We planned, designed, and implemented a web-based system to collect, store, and manage clinical data. The platform was developed by a multidisciplinary team composed of researchers, clinicians, and informatics professionals through different steps. First, we defined the clinical information to be collected. A number of measures were chosen, tapping several clinical risk areas such as neurodevelopmental disorders and emotional and behavioral problems. The web application architecture and process were then designed. The three phases of process design are described in detail: design of the input interface, processing design, and design of the output interface. Finally, the system has been implemented and evaluated. Based on indicators recommended by the National Quality Forum and the Italian National Guidelines, we evaluated the quality of the system and used quantitative measures that were replicable and comparable over time.

Results

We present the implemented architecture and features of Medea Information and Clinical Assessment On-Line (MedicalBIT), and we provide performance measures for the data collected between October 2018 and June 2021. The measured concepts pertain to four domains: access to care, financial impact/cost, experience, and effectiveness.

Conclusions

In this study, we present the successful implementation of an innovative digital tool. The findings of this study show that the implemented web-based platform appears to be an efficient, cost-effective, and feasible way to improve digital care in the field of child psychiatry.
Experiences With a Postpartum mHealth Intervention During the COVID-19 Pandemic: Key Informant Interviews Among Patients, Health Care Providers, and Stakeholders
Authors: Sadural Ernani , Riley Kristen E , Zha Peijia , Pacquiao Dula , Faust Amanda
Published: May 2022

Background

Maternal morbidity and mortality in the United States continue to be a worsening public health crisis, with persistent racial disparities among Black women during the COVID-19 pandemic. Innovations in mobile health (mHealth) technology are being developed as a strategy to connect birthing women to their health care providers during the first 6 weeks of the postpartum period.

Objective

This study aimed to inform a process to evaluate the barriers to mHealth implementation in the context of the COVID-19 pandemic by exploring the experiences of mothers and stakeholders who were directly involved in the pilot program.

Methods

The qualitative design used GoToMeeting (GoTo) individual interviews of 13 mothers and 7 stakeholders at a suburban teaching hospital in New Jersey. Mothers were aged ≥18 years, able to read and write in English or Spanish, had a vaginal or cesarean birth at >20 weeks of estimated gestational age, and were admitted for delivery at the hospital with at least a 24-hour postpartum stay. Stakeholders were part of the hospital network’s obstetrics collaborative subcommittee comprising administrators, physicians, registered nurses, and informatics. Responses were transcribed verbatim and analyzed for emerging themes. The socioecological framework provided a holistic lens for analyzing the multilevel influences on individual experiences.

Results

A total of 3 major themes were identified: mothers experienced barriers from personal situations at home and with services in the hospital and community, which were intensified by the COVID-19 pandemic; the COVID-19 pandemic negatively impacted hospital services, priorities, and individual staff; and mothers and stakeholders had positive experiences and perceptions of the mHealth intervention.

Conclusions

The use and reach of the mHealth intervention were negatively influenced by interrelated factors operating at multiple levels. The system-wide and multilevel impact of the pandemic was reflected in participants’ responses, providing evidence for the need to re-evaluate mHealth implementation with more adaptable systems and structures in place using a socioecological framework.
The Mental Health Impact of Daily News Exposure During the COVID-19 Pandemic: Ecological Momentary Assessment Study (Preprint)
Authors: Kellerman John K , Hamilton Jessica L , Selby Edward A , Kleiman Evan M
Published: May 2022

BACKGROUND

Consumption of distressing news media, which substantially increased during the COVID-19 pandemic, has demonstrable negative effects on mental health.

OBJECTIVE

This study examines the proximal impact of daily exposure to news about COVID-19 on mental health in the first year of the pandemic.

METHODS

A sample of 546 college students completed daily ecological momentary assessments (EMAs) for 8 weeks, measuring exposure to news about COVID-19, worry and optimism specifically related to COVID-19, hopelessness, and general worry.

RESULTS

Participants completed >80,000 surveys. Multilevel mediation models indicated that greater daily exposure to news about COVID-19 is associated with higher same-day and next-day worry about the pandemic. Elevations in worry specifically about COVID-19 were in turn associated with greater next-day hopelessness and general worry. Optimism about COVID-19 mediated the relationship between daily exposure to COVID-19 news and next-day general worry but was not related to hopelessness.

CONCLUSIONS

This study demonstrates the mental health impact of daily exposure to COVID-19 news and highlights how worry about the pandemic contributes over time to hopelessness and general worry.
Dilemma and Breakthrough: Necessity and Legitimacy of Establishing Property Rights for Data Products
Authors: Xia Yijing
Published: May 2022

The development of data products is the essential characteristic and condition of the digital economy, thus giving rise to a new form of ecological competition. The issue of unfair competition and data products is becoming increasingly prominent. At present, for the legal protection of data products, considering the restrictions on laws and regulations, legal remedies are provided according to the anti-unfair competition law. However, as for the disputes in the ownership of data products, the attribute of right becomes an unavoidable focus of dispute in juridical practice. Network operators have devoted an enormous amount of hard work to data products. Based on the theory of the property rights of labor, network operators are entitled to property rights. In the era of artificial intelligence and big data, lawmakers give property rights to data products. It is also an important measure in response to the development of times. This paper briefly analyzes the necessity and legitimacy of establishing property rights for data products.
Teaching of Backspin Serve in Table Tennis
Authors: Pinggui He
Published: May 2022

Backspin serve is a common serve in table tennis matches, and it is also one of the difficult contents for students to master in college table tennis teaching. In order to make students master backspin serve more quickly, the author tries to practice the interest and practicability of serve in the teaching process. This paper expounds and analyzes the feedback information in the concrete implementation and practice in order to further improve the teaching content of physical education in colleges and universities and provide teaching reference for school teaching and sports training.
A Practical Evaluation of Remote Work Issues and the SolarWinds Breach Using the ISO/IEC 27001 Cybersecurity Framework and the ISO/IEC 27002 Guidelines
Authors: Buresh, Ph.D., J.D., LL.M. Donald L.
Published: May 2022

This article outlines the ISO/IEC 27001 framework and the ISO/IEC 27002 guidelines, focusing on their application to two cybersecurity issues. In light of the Covid-19 pandemic, remote work has become commonplace. The factors regarding remote work have led organizations to address the cybersecurity vulnerabilities associated with the activity. ISO/IEC 27001 is one such framework that can effectively mitigate the effects of a cyber-attack. The SolarWinds breach is another example that is discussed in this article. The piece demonstrates that had SolarWinds Corp. implemented the ISO/IEC 27001 framework, the effects of the breach could have been significantly mitigated. The result is that the ISO/IEC 27001 framework is an effective mechanism for alleviating the negative consequences of a cyber-attack.
Experience in the Treatment of Irritable Bowel Syndrome Developed after a New Coronavirus Infection (COVID-19)
Authors: Myazin R. G.
Published: May 2022

Aim. To study the effectiveness of Kolofort® (affinally purified antibodies to tumor necrosis factor α, to the brain-specific protein S-100 and to histamine) in patients with various variants of irritable bowel syndrome (IBS) that developed after a new coronavirus infection (COVID-19).

Materials and methods. Clinical and laboratory data of 32 patients with IBS who had a history of COVID-19 pneumonia were analyzed. Course therapy with Kolofort® is prescribed according to the standard scheme for 3 months. Before and after treatment, the dynamics of the symptoms of IBS was assessed according to the questionnaire, the dynamics of anxiety was assessed according to the Hamilton scale.

Results. There were a statistically significant decrease in the severity of IBS symptoms (normalization of the consistency of the stool, cessation of flatulence, a decrease in abdominal  pain; p < 0.05) and a decrease in anxiety after the end of treatment.

Conclusions. Kolofort® may be effective in eliminating the symptoms of post-infectious  IBS and anxiety that developed after COVID-19.
Pandemia y fundamentos para una renta básica universal como derecho humano emergente en Colombia
Authors: De la Cruz Giraldo Gustavo Nixon , Forero González Omar Osvaldo
Published: May 2022

The current economic crisis caused by biological factors has contributed to the rethinking of past proposals such as accessing an unconditioned income sufficient to allow citizens to meet material needs. Social rights, specifically those focused on access to income, could be considered as committed in plans and programs, but focused on certain population sectors, according to their age, unemployment or contingencies of work or health conditions, established in the different regimes of social security systems, present a limitation, due to their insufficiency in the items for their financing or access,  is subject to compliance with requirements, despite the obligation of the State, even despite its recognition as a human right or as a fundamental right. Given these legal circumstances and the existence of limited plans or programs, it is necessary to ask the following question: What are the foundations and feasibility implications of the adoption of a Universal Basic Income as an emerging human right and its future character? In resolving this question, it is based on the historical review to understand aspects that can be incidents in the legal and economic, due to the relevance as social rights, particularly those of fundamental rank, constitute the starting point that allows progress towards overcoming inequality, projecting its material, real and effective development, with the implementation of mechanisms such as Basic Income as constituting a means of broad coverage of access to income.  unconditionally.
The first evidence of shaking mink syndrome (SMS)-astrovirus infection in farmed minks, China
Authors: Bai Xue , lu rongguang , Li Shuang-Shuang , Hu Bo , Li Hong-Ye , Tian Hong , Liu Weiquan , Yan Xi-Jun , Liu Hao
Published: May 2022

A novel neurological disorder disease, shaking mink syndrome (SMS),
emerged in Denmark and Sweden since 2000. The SMS has seldom been
reported in China, and the causative agent is uncertain. SMS outbreaks
occurred in multiple provinces in 2020, A total of 44 brain samples from
minks associated with SMS were collected from Heilongjiang, Liaoning,
and Shandong provinces, of which 28 samples (63.3%) were SMS-Astrovirus
(SMS-AstV) positive by reverse transcription PCR. Moreover, the complete
coding region sequences (CDS) of a sample collected from a two-month-old
mink (termed SMS-Astv-H1) were amplified by PCR. The complete CDS and
ORF2 sequences of SMS-AstV-H1 were 94.3% and 96.4% identical to an
SMS-AstV strain (GenBank accession number: GU985458). Phylogenetically,
SMS-Astv-H1 was closely related to an SMS-AstV strain (GU985458). Based
on the above results, we describe the SMS-AstV infections related to SMS
among farmed minks in China. Future studies need to focus on
epidemiology, virus isolation, and potential interspecies transmission
of SMS-AstV.
Covid -19 induced atypical pneumonia in an unseparated adult conjoined twin in a remote setup of developing country: management by telemedicine
Authors: Das Anand , Singh Saraj
Published: May 2022

Introduction: Telemedicine is the use of web - based technologies to
provide health care services. Case history: A 40 year old conjoined
twin, known case of dorsal spine tuberculosis contracted Covid-19
infection following which they were shifted to our center. Several
unique challenges were encountered during the course of management.
Nasal Tip Necrosis as a Sign of Leprosy: Case Report
Authors: Alramyan Rana , ALMUTAIRI RAED , Althobaiti Majed
Published: May 2022

Leprosy is a chronic granulomatous disease caused by Mycobacterium
leprae. Leprosy occurrence in Saudi Arabia is rare, it was reported that
242 freshly diagnosed leprosy cases were in Saudi Arabia from 2003 to
2012. This report aims to provide awareness, avoid misdiagnosis, and to
introduce the manifestations of leprosy.
Time With Diabetes Distress and Glycemia-Specific Distress: New Patient-Reported Outcome Measures for the Psychosocial Burden of Diabetes Using Ecological Momentary Assessment in an Observational Study
Authors: Ehrmann Dominic , Schmitt Andreas , Priesterroth Lilli , Kulzer Bernhard , Haak Thomas , Hermanns Norbert
Published: May 2022

Objective

To estimate time with diabetes distress using ecological momentary assessment (EMA) in people with type 1 diabetes and analyze its associations with glycemic management based on continuous glucose monitoring (CGM).

Research Design and Methods

We used EMA to assess diabetes distress in a sample of recently hospitalized adults with type 1 diabetes once a day for 17 consecutive days in an ambulatory setting (NCT03811132). Additionally, participants were asked daily about hypoglycemia distress (<70 mg/dl [3.9 mmol/l]), hyperglycemia distress (>180 mg/dl [10 mmol/l]), and variability distress (glucose fluctuations). Per person, the percentage of days with elevated distress was calculated (time with distress). Multilevel regression was used to analyze daily associations of distress ratings with CGM-derived parameters. EMA-derived associations between diabetes distress and glycemic management were compared to questionnaire-derived associations. 

Results

Data of 178 participants were analyzed. Participants spent 24.1±29.7% of days in diabetes distress, 54.6±26.0% in hyperglycemia distress, 45.2±27.5% in variability distress, and 23.0±19.3% in hypoglycemic distress. In multilevel analyses, higher daily ratings of diabetes distress were significantly associated with hyperglycemia (β=0.41). Results showed high between-person variability as explanation of variance of the models ranged between 22.2% and 98.8%. EMA-derived diabetes distress showed a significant association with mean glucose (r=0.25), while questionnaire-based diabetes distress did not (r=0.10). Prospectively, time with diabetes distress was associated with HbA1c at the 3-month follow-up (r=0.27), while questionnaire-based distress showed no association (r=0.11).

Conclusions

Time with distress assessed by EMA showed a comparative advantage over questionnaire-based assessment of diabetes distress regarding associations with glycemic management.
Model Group Investigation dan Kemampuan Komunikasi Matematik dalam Pembelajaran Matematika Siswa Kelas XI IPA SMA Negeri 2 Cirebon
Authors: Nopriana Tri
Published: May 2022

Tujuan penelitian ini adalah untuk membandingkan kemampuan komunikasi matematika siswa pada tingkat Sekolah Menengah Atas. Penelitian dilakukan di SMA Negeri 2 Cirebon dengan metode quasi eksperimen dengan melibatkan 62 Siswa Kelas XI sebagai sampel. Pemilihan sampel menggunakan cluster random sampling. Instrumen yang dugunakan dalam mengumpulkan data adalah tes essay. Hasil penelitian menyimpulkan bahwa: (1) Kemampuan komunikasi matematika siswa setelah diterapkan model pembelajaran kooperatif tipe Group Investigation  lebih baik dari pada kemampuan komunikasi matematika siswa yang menggunakan pembelajaran konvensinal. (2) Rata-rata kemampuan komunikasi matematika siswa  yang menggunakan pembelajaran kooperatif tipe Group Investigation lebih tinggi dari rata-rata kemampuan komunikasi matematika siswa yang menggunakan pembelajaran konvensional.
Meningkatkan Kemampuan Berpikir Kritis Siswa Melalui Pembelajaran Dengan Pendekatan Metakognitif
Authors: . Tata
Published: May 2022

Tujuan utama dari penelitian ini adalah untuk mengkaji pembelajaran matematika dengan pendekatan metakognitif terhadap peningkatan kemampuan berpikir kritis. Desain penelitian ini adalah eksperimen kelompok kontrol pretes-postes dengan menggunakan dua kelompok. Kelompok eksperimen memperoleh pembelajaran dengan pendekatan metakognitif dan kelompok kontrol memperoleh pembelajaran biasa. Untuk memperoleh data penelitian digunakan instrumen berupa tes kemampuan berpikir kritis berbentuk uraian. Subjek penelitian ini adalah siswa kelas VII sebuah Sekolah Menengah Pertama di Cianjur dengan mengambil sampel dua kelas sebagai kelompok eksperimen dan kelompok kontrol yang dilakukan dengan cara purposive sampling. Analisis kuantitatif dilakukan terhadap hasil tes berupa skor pretes, postes, dan gain ternormalisasi kemampuan berpikir kritis dengan mengunakan uji-t dan ANOVA satu jalur. Berdasarkan analisis data, diperoleh kesimpulan  bahwa peningkatan kemampuan berpikir kritis siswa yang belajar dengan pendekatan metakognitif lebih tinggi daripada siswa yang belajar dengan pembelajaran biasa. Di samping itu, terdapat perbedaan peningkatan kemampuan berpikir kritis antara siswa kelompok tinggi dengan siswa kelompok sedang,  antara siswa kelompok tinggi dengan siswa kelompok rendah, serta tidak terdapat perbedaan peningkatan kemampuan berpikir kritis antara siswa kelompok sedang dengan siswa kelompok rendah setelah memperoleh pembelajaran dengan pendekatan metakognitif.
Implementasi Basis Data Spasial Dalam Penyebaran Potensi Desa Di Kabupaten Bandung
Authors: Rosadi Rudi , Kartiwa Alit , Astuti Dyah Kusuma
Published: May 2022

Salah satu implementasi dari sistem basis data spasial digunakan dalam membangun Sistem informasi Geografis (SIG). SIG merupakan sistem berbasis spasial yang dapat digunakan dalam analisis dan pengambilan keputusan. Dengan SIG ini diharapkan dapat membantu dalam pengembangan dan penyebaran potensi di suatu wilayah. Karena berdasarkan data Potensi Desa Kabupaten Bandung tahun 2008 yang di dapat dari Badan Pusat Statistik menunjukan tingkat kepadatan penduduk tiap desa yang tidak merata, rasio kelahiran yang tinggi, fasilitas dan tenaga kesehatan serta fasilitas ekonomi lainnya yang jumlahnya kurang atau tidak sesuai.
Penelitian ini menganalisis pengaruh letak geografis suatu desa di Kabupaten Bandung terhadap karakteristik kelompok desa yang terbentuk dengan menggunakan analisis K-Means dan menampilkannya ke dalam bentuk peta digital . Sehingga diharapkan pencarian informasi lebih efektif dan pengembangan potensi suatu wilayah dapat dilakukan lebih optimal.
A Digital Planning Tool for Shaping Up the Landscaping Architecture
Authors:   Department of Software & Information Systems, University of Mauritius, Reduit, Mauritius., Qaiyum Mohabuth Abdool , Haashim Gunnoo Ibrahim ,   GBLC Office, Aerow ECM World Ltd, Grand Baie, Mauritius.
Published: May 2022

Landscape architecture is a comparatively new concept and is gaining prominence in town and country planning exercises. People marveled at the design of new towns when the infrastructure looks nice and well placed. However, when the planning exercise is not done properly this results in the implementation of poor infrastructure with narrow roads, lack of green spaces, no parking spots, congested streets and so. Architects are still using traditional hand drawing for their designs and sketches which have several limitations. Developing a landscape architecture planning system with appropriate tools will facilitate architects’ tasks and others to have an appropriate to ensure proper landscape planning without unnecessarily wasting time manually. This paper aims to present a desktop application with features for generating appropriate cartography which allows users to place appropriate objects representing real-world urban structures and buildings. The Waterfall methodology was used to build and implement the proposed system. The latter is expected to help in the reduction of parking problems and increase the number of green areas in towns. The application proposed includes appropriate validation techniques to allow users to plan a site and made sure that the standards set for parking spaces and green areas are being respected.
Marine Policy in Holding and Handling Marine Natural Asset as An Attempt to Recognize Indonesia as The Sector’s Maritime Axis
Authors: Agung Hario Istiqlal , Almubaroq Hikmat Zakky
Published: May 2022

The maritime axis is now increasingly popular and attracts the attention of many parties, including the mass media which also often brings up the term in the news in recent times. The emergence of the term cannot be separated from the idea of ​​President Joko Widodo who wants to make Indonesia as the world's maritime axis, also wants to make Indonesian waters a territory safe waters in the world for all marine activities, and for that, the government will ensure security and safety of sea transportation carried out by the community and business actors. The development of maritime affairs cannot be done all at once. To optimize maritime development at the national level, regional and global, and especially in achieving the world maritime axis requires direction, orientation, strategy, and anticipation of effective, consistent, and sustainable development. Therefore, the researcher saw the implementation of the maritime axis from a policy perspective. Issues that will be the focus of this research are firstly how the development of the world maritime axis concept in Indonesia, secondly how to implement Indonesia's maritime axis from a policy perspective. The purpose of this research is to know the development of the concept of the world maritime axis in Indonesia and its implementation. Based on the results of research that Indonesia has implemented the concept of the world maritime axis by issuing policies and their implementation; it is recommended that Indonesia has a pivot law maritime world to answer challenges to realize Indonesia's excellence. The uses of this research order to information and development of law and practice as input for stakeholders including the Government, experts, academics, practitioners and the public.
Analysis of the Breakdown Voltage of Soyabean Oil as an Alternative to Mineral Oil
Authors: Ikyumbur Terseer J. , Iorhom Andrew L. , Gbaorun Frederick , Akila Simdet , Agaku Msughter R. , Ayaakaa Terkimbi D.
Published: May 2022

The reliability of an insulating oil depends on certain basic characteristics, which can affect the overall performance of the transform. In this work, the physio-chemical characteristics and breakdown voltage of refined Soyabean oil have been analyzed. The oil characteristics such as density, viscosity, moisture content, sludge, acidity, flash point and breakdown voltage (BDV) of refined Soyabean oil (SO) were experimentally analyzed in the Laboratory. The density, viscosity, moisture content, acidity, sludge, and breakdown voltage of the SO were within the IEC standard. This shows that the refined soyabean oil could be a suitable replacement of mineral oil. The work has however, recorded a small flash point of 38oC. The researchers concluded that the characteristics of soyabean oil could be significantly improve if the oil is blended with other oils.