bluuebunny/crossref_metadata_2025 huggingface dataset:
Designing Parameters to Reshape the Inverter Output Impedance Based on the D-Split Method under Weak Grid Conditions
Authors: Wang Su’e , Zhou Guangyuan , Hao Pengfei , Chen Jingwen
Published: December 2023

Novel energy generation technologies, such as high-permeability wind power and photovoltaic systems, exhibit inherent intermittency, randomness, and volatility. During periods of energy production from these sources, the impedance of the electrical grid frequently experiences significant fluctuations. Consequently, the grid manifests characteristics akin to a weak grid, highlighting the challenges associated with integrating renewable energy sources with variable output profiles. These fluctuations lead to a shift in resonance spikes of the LCL-type filter towards the lower frequency band, consequently impacting the stability of inverter grid connections. To mitigate this issue, the present study introduces a novel approach integrating the D-split method and a proportional–differential feedforward strategy. This combination aims to reshape the inverter’s output impedance, ensuring its consistent stability even amidst significant fluctuations in grid impedance. In this research, the optimal controller parameters for systems operating under robust grid conditions are initially determined. This selection process involves the application of the D-split method, supported by graphical visualization. Additionally, the amplitude and phase angle margin tester is employed while considering the system bandwidth as a limiting constraint. Moreover, accounting for the influence of grid impedance, the D-split method is reapplied to ascertain the most suitable values for the proportional–differential feedforward parameters. This adjustment aims to enhance the adaptability of the grid-connected inverter specifically in scenarios characterized by a weak grid. The hardware-in-the-loop (HIL) simulation results demonstrate that despite the presence of harmonics within the grid and a short circuit impedance ratio (SCR) of 3, the inverter maintains grid stability and effectively suppresses harmonics. Moreover, the total harmonic distortion factor (THD) of the grid-connected current remains below 5%.
Adaptability Analysis of the Evergreen Pioneer Tree Species Schima superba to Climate Change in Zhejiang Province
Authors: Wu Chuping , Fan Jianzhong , Xu Yonghong , Jiang Bo , Jiao Jiejie , Yao Liangjin
Published: December 2023

In recent years, frequent global climate change has led to extreme weather events, such as high temperatures and droughts. Under the backdrop of climate change, the potential distribution zones of plants will undergo alterations. Therefore, it is necessary to predict the potential geographical distribution patterns of plants under climate change. Schima superba, a plant species with significant ecological and economic value, plays a crucial role in ecological restoration and maintaining environmental stability. Therefore, predicting potential changes in its suitable habitat in Zhejiang Province is significant. The MaxEnt model and combined data from 831 monitoring sites where Schima superba is distributed in Zhejiang Province with 12 selected bioclimatic variables were used to predict habitat suitability adaptability. We found that (1) the average AUC value of the MaxEnt model in repeated experiments was 0.804, with a standard deviation of 0.014, which indicates high reliability in predictions. (2) The total suitable habitat area for Schima superba in Zhejiang Province (suitability value > 0.05) is 87,600 km2, with high-suitability, moderate-suitability, and low-suitability areas covering 29,400 km2, 25,700 km2, and 32,500 km2, respectively. (3) Likewise, elevation, precipitation, and temperature are the dominant climatic variables that influence the distribution of Schima superba. Schima superba mainly occurs in areas with an elevation above 500 m and precipitation over 140 mm during the hottest season. The probability of Schima superba distribution reaches its peak at elevations between 1200 and 1400 m. Here, the precipitation ranges from 300 to 350 mm with high humidity, between 160 and 170 mm during the hottest season, and an annual temperature range between 28 and 31 °C. Therefore, our results indicate that climate change significantly affects the suitable habitat area of Schima superba. We also reveal the ecological characteristics and adaptation mechanisms of Schima superba in different geographical regions of Zhejiang Province. Future research should focus on the relationship between plant adaptation strategies and environmental changes, as well as applications in ecosystem protection and sustainable development, to promote the development and application of plant habitat adaptability research.
Xylitol Production by Debaryomyces hansenii in Extracted Olive Pomace Dilute-Acid Hydrolysate
Authors: Morais Ana Rita C. , Duarte Luís C. , Lourenço Pedro , Torrado Ivone , Brás Teresa , Neves Luísa A. , Carvalheiro Florbela
Published: December 2023

The extracted olive pomace (EOP) is an industrial lignocellulosic by-product of olive pomace oil extraction, currently mainly used for energy production through combustion. In this work, the hemicellulosic fraction of EOP was selectively hydrolyzed by diluted acid hydrolysis to obtain pentose-rich hydrolysates that can potentially be upgraded by Debaryomyces hansenii, targeting xylitol production. The monosaccharides and degradation by-products released along the pre-treatment were quantified and several detoxification methods for the removal of potentially toxic compounds were evaluated, including pH adjustment to 5.5, the use of anion-exchange resins, adsorption into activated charcoal, concentration by evaporation, and membrane techniques, i.e., nanofiltration. The latter approach was shown to be the best method allowing the full removal of furfural, 41% of 5-hydroxymethylfurfural, 54% of acetic acid, and 67% of the phenolic compounds present in the hydrolysate. The effects of the supplementation of both non-detoxified and detoxified hydrolysates were also assessed. The non-detoxified hydrolysate, under aerobic conditions, supported the yeast growth and xylitol production at low levels. Supplementation with the low-cost corn steep liquor of the nanofiltration detoxified hydrolysate showed a higher xylitol yield (0.57 g/g) compared to the non-detoxified hydrolysate. The highest xylitol productivity was found in hydrolysate detoxified with anionic resins (0.30 g/L·h), which was 80% higher than in the non-detoxified culture medium. Overall, the results showed that EOP dilute acid hydrolysates can efficiently be used for xylitol production by D. hansenii if detoxification, and supplementation, even with low-cost supplements, are performed.
Torulaspora delbrueckii Improves Organoleptic Properties and Promotes Malolactic Fermentation in Carbonic Maceration Wines
Authors: Ruiz-de-Villa Candela , Gombau Jordi , Poblet Montse , Bordons Albert , Canals Joan Miquel , Zamora Fernando , Reguant Cristina , Rozès Nicolas
Published: December 2023

This study investigates the impact of inoculating Torulaspora delbrueckii (Td) strains during the initial phase of carbonic maceration (CM) vinification, aiming to enhance the fermentative process and unique characteristics of CM wines. CM is a winemaking technique where whole bunches (without destemming and crushing) are enclosed in tanks filled with carbon dioxide, inducing intracellular fermentation. This study compares the effects of two Td strains on the MLF performance and sensory characteristics of CM wines using both inoculated and spontaneous MLF strategies. Although general physicochemical parameters remained consistent across conditions, organoleptic attributes showed significant differences due to T. delbrueckii presence. T. delbrueckii introduction during CM resulted in wines with increased anthocyanin content and a particular volatile profile. Isoamyl acetate, a key aroma in CM wines, was notably elevated, especially in the TdP strain. Sensory evaluations also revealed distinctions, with TdV wines displaying more pronounced aromas of red fruit, banana, and grass. Regarding MLF, T. delbrueckii presence notably enhanced performance, particularly in spontaneous MLF cases, accelerating fermentation completion. Inoculating the Oenococcus oeni strain OoVP41 also shortened MLF duration. These findings highlight the potential of Td strains to improve MLF efficiency and sensory attributes in CM wines. Using T. delbrueckii strains strategically enables winemakers to optimize MLF and improve sensory profiles, offering an opportunity to produce higher-quality CM wines.
The Genome of the Yellow Mealworm, Tenebrio molitor: It’s Bigger Than You Think
Authors: Oppert Brenda , Dossey Aaron T. , Chu Fu-Chyun , Šatović-Vukšić Eva , Plohl Miroslav , Smith Timothy P. L. , Koren Sergey , Olmstead Morgan L. , Leierer Dewey , Ragan Gail , Johnston J. Spencer
Published: December 2023

Background: Insects are a sustainable source of protein for human food and animal feed. We present a genome assembly, CRISPR gene editing, and life stage-specific transcriptomes for the yellow mealworm, Tenebrio molitor, one of the most intensively farmed insects worldwide. Methods: Long and short reads and long-range data were obtained from a T. molitor male pupa. Sequencing transcripts from 12 T. molitor life stages resulted in 279 million reads for gene prediction and genetic engineering. A unique plasmid delivery system containing guide RNAs targeting the eye color gene vermilion flanking the muscle actin gene promoter and EGFP marker was used in CRISPR/Cas9 transformation. Results: The assembly is approximately 53% of the genome size of 756.8 ± 9.6 Mb, measured using flow cytometry. Assembly was complicated by a satellitome of at least 11 highly conserved satDNAs occupying 28% of the genome. The injection of the plasmid into embryos resulted in knock-out of Tm vermilion and knock-in of EGFP. Conclusions: The genome of T. molitor is longer than current assemblies (including ours) due to a substantial amount (26.5%) of only one highly abundant satellite DNA sequence. Genetic sequences and transformation tools for an insect important to the food and feed industries will promote the sustainable utilization of mealworms and other farmed insects.
Assessment of the Long-Range NMR C,H Coupling of a Series of Carbazolequinone Derivatives
Authors: Monroy-Cárdenas Matías , Gavín José A. , Araya-Maturana Ramiro
Published: December 2023

Synthesis, the complete 1H- and 13C-NMR assignments, and the long-range C,H coupling constants (nJC,H) of some hydrogen-deficient carbazolequinones, assessed by a J-HMBC experiment, are reported. In these molecules, the protons, used as entry points for assignments, are separated by several bonds with non-protonated atom carbons. Therefore, the use of long-range NMR experiments for the assignment of the spectra is mandatory; we used HSQC and HMBC. On the other hand, the measured heteronuclear (C,H) coupling constants 2J to 5J) allow us to choose the value of the long-range delay used in the HMBC experiment less arbitrarily in order to visualize a desired correlation in the spectrum. The chemical shifts and the coupling constant values can be used as input for assignments in related chemical structures.
Tonabersat Significantly Reduces Disease Progression in an Experimental Mouse Model of Multiple Sclerosis
Authors: Kwakowsky Andrea , Chawdhary Bhavya , de Souza Antonio , Meyer Emily , Kaye Andrew H. , Green Colin R. , Stylli Stanley S. , Danesh-Meyer Helen
Published: December 2023

Multiple sclerosis (MS) is a neurodegenerative disease marked by chronic neuroinflammation thought to be mediated by the inflammasome pathway. Connexin 43 (Cx43) hemichannels contribute to the activation of the inflammasome through the release of adenosine triphosphate (ATP) inflammasome activation signals. The objective of the study was to evaluate if the Cx43 hemichannel blocker, tonabersat, is effective in modulating the inflammatory response and reducing disability in the myelin oligodendrocyte glycoprotein 35–55-induced experimental autoimmune encephalomyelitis (MOG35–55 EAE) model of MS. Here, we show that the Cx43 hemichannel blocking drug, tonabersat, significantly reduced expression of neuroinflammatory markers for microglial activation (ionized calcium-binding adapter molecule 1 (Iba1)) and astrogliosis (glial fibrillary acidic protein (GFAP)) while preserving myelin basic protein (MBP) expression levels in the corpus callosum, motor cortex, and striatum regions of the brain in MOG35–55 EAE mice. Reduced NOD-like receptor protein 3 (NLRP3) inflammasome complex assembly and Caspase-1 activation confirmed the drug’s mode of action. MOG35–55 EAE mice showed clinical signs of MS, but MOG35–55 EAE mice treated with tonabersat retained behavior closer to normal. These data suggest that clinical trial phase IIb-ready tonabersat may merit further investigation as a promising candidate for MS treatment.
WGA-M001, a Mixture of Total Extracts of Tagetes erecta and Ocimum basilicum, Synergistically Alleviates Cartilage Destruction by Inhibiting ERK and NF-κB Signaling
Authors: Oh Eunjeong , Jang Hahyeong , Ok Subin , Eom Jiwon , Lee Hyunyong , Kim Sung Hun , Kim Jong Hwa , Jeong Yu Mi , Kim Kyeong Jin , Yun Seung Pil , Kwon Hyung-Jun , Lee In-Chul , Park Ji-Young , Yang Siyoung
Published: December 2023

Tagetes erecta and Ocimum basilicum are medicinal plants that exhibit anti-inflammatory effects against various diseases. However, their individual and combined effects on osteoarthritis (OA) are unknown. Herein, we aimed to demonstrate the effects of T. erecta, O. basilicum, and their mixture, WGA-M001, on OA pathogenesis. The administration of total extracts of T. erecta and O. basilicum reduced cartilage degradation and inflammation without causing cytotoxicity. Although WGA-M001 contained lower concentrations of the individual extracts, it strongly inhibited the expression of pathogenic factors. In vivo OA studies also supported that WGA-M001 had protective effects against cartilage destruction at lower doses than those of T. erecta and O. basilicum. Moreover, its effects were stronger than those observed using Boswellia and Perna canaliculus. WGA-M001 effectively inhibited the interleukin (IL)-1β-induced nuclear factor kappa-light-chain-enhancer of the activated B cell (NF-κB) pathway and ERK phosphorylation. Furthermore, RNA-sequence analysis also showed that WGA-M001 decreased the expression of genes related to the IL-1β-induced NF-κB and ERK signaling pathways. Therefore, WGA-M001 is more effective than the single total extracts of T. erecta and O. basilicum in attenuating OA progression by regulating ERK and NF-κB signaling. Our results open new possibilities for WGA-M001 as a potential therapeutic agent for OA treatment.
Lipids Metabolism and Cardiometabolic Diseases
Authors: Gaggini Melania , Vassalle Cristina
Published: December 2023

Cardiometabolic diseases (CMD) remains the major cause of morbidity and mortality in Western countries, with a marked increased in the last years [...]
SrTiO3-SrVO3 Ceramics for Solid Oxide Fuel Cell Anodes: A Route from Oxidized Precursors
Authors: Macías Javier , Frade Jorge R. , Yaremchenko Aleksey A.
Published: December 2023

Perovskite-type Sr(Ti,V)O3-δ ceramics are promising anode materials for natural gas- and biogas-fueled solid oxide fuel cells, but the instability of these phases under oxidizing conditions complicates their practical application. The present work explores approaches to the fabrication of strontium titanate-vanadate electrodes from oxidized precursors. Porous ceramics with the nominal composition SrTi1−yVyOz (y = 0.1–0.3) were prepared in air via a solid state reaction route. Thermal processing at temperatures not exceeding 1100 °C yielded composite ceramics comprising perovskite-type SrTiO3, pyrovanadate Sr2V2O7 and orthovanadate Sr3(VO4)2 phases, while increasing firing temperatures to 1250–1440 °C enabled the formation of SrTi1−yVyO3 perovskites. Vanadium was found to substitute into the titanium sublattice predominantly as V4+, even under oxidizing conditions at elevated temperatures. Both perovskite and composite oxidized ceramics exhibit moderate thermal expansion coefficients in air, 11.1–12.1 ppm/K at 30–1000 °C, and insignificant dimensional changes induced by reduction in a 10%H2-N2 atmosphere. The electrical conductivity of reduced perovskite samples remains comparatively low, ~10−1 S/cm at 900 °C, whereas the transformation of oxidized vanadate phases into high-conducting SrVO3−δ perovskites upon reduction results in enhancement in conductivity, which reaches ~3 S/cm at 900 °C in porous composite ceramics with nominal composition SrTi0.7V0.3Oz. The electrical performance of the composite is expected to be further improved by optimization of the processing route and microstructure to facilitate the reduction of the oxidized precursor and attain better percolation of the SrVO3 phase.
Management of Pediatric Urolithiasis in an Italian Tertiary Referral Center: A Retrospective Analysis
Authors: Lasorsa Francesco , Caliolo Claudia , Silecchia Antonia , Laricchiuta Nicola , Raguso Michele , Ditonno Pasquale , Lucarelli Giuseppe
Published: December 2023

Background and Objectives: In recent years, the prevalence of pediatric urolithiasis has increased in North America and Western countries, though it is endemic in developing countries. The aim of this study is to describe the experience of a tertiary pediatric referral center in the surgical management of pediatric urolithiasis. Materials and Methods: We retrospectively reviewed the experience of patients ≤ 16 years old affected by urinary stones who underwent surgery. Results: From April 2021 to September 2023, 31 pediatric patients underwent surgical procedures for stone diseases at our department: 13 preschool-aged (1–5 years) and 18 school-aged (6–16 years) children. During this period, 12 URSs, 17 RIRSs, and 2 PCNLs were recorded. Five patients had residual fragments at first, so three of them underwent a second endourological lithotripsy (2 RIRSs and 1 URS). Complete clearance was finally achieved in 27 patients. The stone composition was evaluated in 25 cases. Conclusions: Numerous innovations in the surgical treatment of pediatric urolithiasis have resulted from the development of smaller devices and new technology. Our results show how, in experienced centers, retrograde and percutaneous lithotripsy are safe and effective procedures for use in pediatric populations.
Oxidative Stress Induced by Chemotherapy: Evaluation of Glutathione and Its Related Antioxidant Enzyme Dynamics in Patients with Colorectal Cancer
Authors: Chiang Feng-Fan , Huang Shih-Chien , Yu Pei-Ting , Chao Te-Hsin , Huang Yi-Chia
Published: December 2023

One of the mechanisms of chemotherapy is to increase the oxidative stress of cancer cells, leading to their apoptosis. Glutathione (GSH) and its related antioxidant enzymes might be stimulated to cope with increased oxidative stress during chemotherapy. Here, we studied the fluctuation in oxidative stress and GSH-related antioxidant capacities before tumor resection, after tumor resection, and after resection either with or without chemotherapy in patients with colorectal cancer (CRC). This was a cross-sectional and follow-up design. We followed patients before having tumor resection (pre-resection), one month after tumor resection (post-resection), and after the first scheduled chemotherapy (post-chemo). If patients were required to receive chemotherapy after tumor resection, they were assigned to the chemotherapy group. Eligible patients were scheduled to undergo six to twelve cycles of chemotherapy at 2-week intervals and received single, double, or triple chemotherapeutic drugs as required. Those patients who did not require chemotherapy were assigned to the non-chemotherapy group. Indicators of oxidative stress and GSH-related antioxidant capacities were determined at the above three time points. We found in 48 patients of the chemotherapy group and in 43 patients of the non-chemotherapy group different fluctuations in levels of oxidative stress indicators and GSH-related antioxidant capacities starting from pre-resection, post-resection through the post-chemo period. Both groups showed significantly or slightly increased levels of advanced oxidation protein products (AOPP), GSH, and its related enzymes in tumor tissues compared to adjacent normal tissues. Patients in the chemotherapy group had significantly lower plasma levels of GSH and glutathione disulfide (GSSG), but had significantly higher plasma glutathione peroxidase and glutathione reductase activities than patients in the non-chemotherapy group post-chemo. Plasma levels of malondialdehyde and AOPP were positively or negatively associated with GSH and GSSG levels post-chemo after adjustment for age, sex, and histological grading in patients receiving chemotherapy. These significant associations were, however, not seen in patients without chemotherapy. Patients with CRC may require higher GSH demands to cope with a greater oxidative stress resulting from chemotherapy.
Effect of Moisture on the Mechanical Properties of Wood–Plastic Composites Hybridized with Metal Grid Layers
Authors: Perišić Srdjan , Kalevski Katarina , Grujić Aleksandar , Nedeljković Dragutin , Stajić-Trošić Jasna , Radojević Vesna
Published: December 2023

Wood–plastic composites (WPCs) are some of the most common modern composite materials for interior and exterior design that combine natural waste wood properties and the molding possibility of a thermoplastic polymer binder. The addition of reinforcing elements, binding agents, pigments, and coatings, as well as changes to the microstructure and composition, can all affect the quality of WPCs for particular purposes. To improve the properties, hybrid composite panels of WPCs with 30 wt. % and 40 wt. % of wood content and reinforced with one or three metal grid layers were prepared sequentially by extrusion and hot pressure molding. The results show an average 20% higher moisture absorption for composites with higher wood content. A high impact test (HIT) revealed that the absorbed energy of deformation increased with the number of metal grid layers, regardless of the wood content, around two times for all samples before water immersion and around ten times after water absorption. Also, absorbed energy increases with raised wood content, which is most pronounced in three-metal-grid samples, from 21 J to 26 J (before swelling) and from 15 J to 24 J (after swelling). Flexural tests follow the trends observed by HIT, indicating around 65% higher strength for samples with three metal grid layers vs. samples without a metal grid before water immersion and around 80% higher strength for samples with three metal grid layers vs. samples without a grid after water absorption. The synthesis route, double reinforcing (wood and metal), applied methods of characterization, and optimization according to the obtained results provide a WPC with improved mechanical properties ready for an outdoor purpose.
The Latest Occurrence of Stephanorhinus hundsheimensis (Rhinocerotidae) in Europe: The Skeletons from the Cova del Rinoceront Site (Castelldefels, Barcelona)
Authors: García-Fernández David , Cerdeño Esperanza , Sanz Montserrat , Daura Joan
Published: December 2023

New rhino remains recovered from Cova del Rinoceront (Castelldefels, Barcelona) confirm the presence of Stephanorhinus hundsheimensis (Toula, 1902) at the site and the taxon’s persistence until the late Middle–early Upper Pleistocene in Europe, that is, its latest documented occurrence. The three individuals recovered from the site are compared with specimens of other Pleistocene species, including those of S. hemitoechus, S. kirchbergensis and Coelodonta antiquitatis, but their anatomical characteristics (a long skull, moderate occipital elevation, partial nasal septum, and slender zygomatic arch) do not coincide with the latter’s documented features. Certain similarities are found with the most frequently occurring rhinocerotid at that time in the Iberian Peninsula, S. hemitoechus, but the cranial features of the latter differ. The anatomical characteristics of the Cova del Rinoceront individuals coincide most closely with those of S. hundsheimensis (i.e., a high occipital face, with rounded proximolateral angles and oblique lateral borders, as well as the frontoparietal angle, and facial development). Despite the marked overlaps in the general measurements of S. hundsheimensis and S. hemitoechus, many (cranial and postcranial) dimensions of the Cova del Rinoceront individuals coincide more closely with those of the former, although some bone proportions are more similar to those of the latter specimens. Therefore, S. kirchbergensis and C. antiquitatis can be discarded as they tend to be larger, more robust species.
Estimating Fine Fuel Load Using Sentinel-2A Imagery and Machine Learning: A Case Study in the Mountainous Forests of Changsha, China
Authors: Deng Lei , Yan Enping , Jiang Jiawei , Mo Dengkui
Published: December 2023

Fine fuel load (FFL) is a crucial variable influencing the occurrence of wildfire. Accurate knowledge of the distribution of FFL in mountainous forests is essential for ongoing wildfire risk management and the stability of mountain ecosystems. Traditional methods of estimating forest fuel load typically involve ground surveys combined with remote sensing, which can be costly and inefficient. Therefore, low-cost, large-scale FFL estimation remains challenging. In this study, Sentinel-2A satellite imagery from the Changsha forest region was used as the data source. Firstly, different feature variables were constructed based on false-color (B843), true-color (B432), four-band (B8432) combinations, and the Normalized Difference Water Index (NDWI). Subsequently, a machine learning approach based on random convolution was employed to estimate FFL. This study also included accuracy assessments of the estimation results and the creation of FFL maps for the study area. The results showed that the FFL estimation based on the B8432 band combination achieved the highest accuracy, with RMSE and R2 values of 5.847 t·hm−2 and 0.656, respectively. FFL estimation results based on false-color imagery followed, with true-color imagery and NDWI index-based estimation results exhibiting lower accuracy. This study offers critical FFL insights using random convolution techniques applied to Sentinel-2A imagery, enhancing the ability to monitor and manage forest fuel conditions effectively, thereby facilitating more informed regional wildfire risk management strategies.
Assessment of the Impact of Surface Water Content for Temperate Forests in SAR Data at C-Band
Authors: Cagnina Costanza , Marino Armando , Silva-Perez Cristian , Ruiz-Ramos Javier , Suarez Juan
Published: December 2023

This study addresses the escalating challenges posed by forest drought and wildfires, emphasizing the critical need to monitor forest conditions to mitigate associated risks. While traditional optical sensors have proven valuable for vegetation surface water (VSW) assessment, their limitations in regions with persistent cloud cover prompt an exploration of the alternatives. The study advocates the efficacy of Synthetic Aperture Radar (SAR) systems, known for their cloud-penetrating capabilities and sensitivity to changes in dielectric properties. Leveraging Sentinel-1 C-band dual polarization SAR data, the research investigates the impact of Vegetation Surface Water (VSW) on backscatter coefficients in a temperate coniferous forest through the application of generalized linear models. Despite the challenges posed by precipitation and canopy characteristics, the study unveils detectable modulation in backscatter, particularly in VH polarization, indicating the potential of SAR-based methods in forest monitoring. The occurrence of rain on the day of Sentinel-1 image acquisition, and therefore the presence of VSW, triggers an increase of 0.35 dB in VV backscatter, and an increase of 0.45 dB in VH backscatter. The findings underscore the importance of considering surface water content in radar backscatter analyses for accurate biomass estimations and change detection, suggesting avenues for future research and potential correction mechanisms.
An Application of Quality Function Deployment to Explore a Product Design Concept—A Case Study of a Triple-Effect Green Energy Generator for the Taiwan Environment
Authors: Liu Shuo-Fang , Wei Yu-Shan , Guo Hong-Kai , Su An-Yu
Published: December 2023

Taiwan has been actively promoting renewable energy technologies and applications to achieve sustainable development goals, aiming to increase the share of renewable energy in the domestic electricity structure. Among them, solar energy and wind energy have been developed and matured, especially solar water heaters, which have been popularized in people’s homes. This study proposes a triple-effect green energy generator, which is an innovative concept of combining a solar water heater with a wind turbine and thermoelectric devices, which have been gradually emphasized in recent years. Therefore, quality function deployment (QFD) was used to investigate the customer requirements and engineering measures of the product, and the results show that the product has leakage protection, is waterproof and rustproof, and does not affect health; furthermore, the product is resistant to high temperature and heavy rain, has a stable base, is suitable for most residential conditions, has 24 h operation, and has a remarkable power generation effect. Electricity can be used for general household appliances, which are the most important customer needs, and small wind turbines, energy management systems, and exterior materials are the three most important engineering initiatives to be emphasized. Although this study only analyzes preliminary design concepts, the results can provide references for related or similar product development strategies and contribute to the progress of Taiwan’s sustainable development goals.
Record Linkage for Malaria Deaths Data Recovery and Surveillance in Brazil
Authors: Garcia Klauss Kleydmann Sabino , Xavier Danielly Batista , Soremekun Seyi , Abrahão Amanda Amaral , Drakeley Chris , Ramalho Walter Massa , Siqueira André M.
Published: December 2023

Objective: The objective is to describe the results and the methodological processes of record linkage for matching deaths and malaria cases. Methods: A descriptive cross-sectional study was conducted with probabilistic record linkage of death and malaria cases data in Brazil from 2011 to 2020 using death records from the Mortality Information System (SIM) and epidemiological data from the Notifiable Diseases Information System (Sinan) and Epidemiological Surveillance Information Systems for malaria (Sivep-Malaria). Three matching keys were used: patient’s name, date of birth, and mother’s name, with an analysis of cosine and Levenshtein dissimilarity measures. Results: A total of 490 malaria deaths were recorded in Brazil between 2011 and 2020. The record linkage resulted in the pairing of 216 deaths (44.0%). Pairings where all three matching keys were identical accounted for 30.1% of the total matched deaths, 39.4% of the matched deaths had two identical variables, and 30.5% had only one of the three key variables identical. The distribution of the variables of the matched deaths (216) was similar to the distribution of all recorded deaths (490). Out of the 216 matched deaths, 80 (37.0%) had poorly specified causes of death in the SIM. Conclusions: The record linkage allowed for the detailing of the data with additional information from other epidemiological systems. Record linkage enables data linkage between information systems that lack interoperability and is an extremely useful tool for refining health situation analyses and improving malaria death surveillance in Brazil.
High Tuberculosis Preventive Treatment Uptake and Completion Rates Using a Person-Centered Approach among Tuberculosis Household Contact in Yogyakarta
Authors: Felisia Felisia , Triasih Rina , Nababan Betty Weri Yolanda , Sanjaya Guardian Yoki , Dewi Setyogati Candra , Rahayu Endang Sri , Unwanah Lana , du Cros Philipp , Chan Geoffrey
Published: December 2023

Coverage of tuberculosis preventive treatment (TPT) in Indonesia is inadequate, and persons who start TPT often do not complete treatment. In 2020, Zero TB Yogyakarta implemented person-centered contact investigation and shorter TPT regimen provision in collaboration with primary health care centers. Between 1 January 2020 and 31 August 2022, we assessed eligibility for TPT among household contacts of persons with bacteriologically confirmed TB (index cases) and offered them a 3-month TPT regimen (3RH or 3HP). A dedicated nurse monitored contacts on TPT for treatment adherence and side effects every week in the first month and every two weeks in the next months. Contacts were also able to contact a nurse by phone or ask for home visits at any point if they had any concerns. A total of 1016 contacts were eligible for TPT: 772 (78.8%) started short regimen TPT with 706 (91.5%) completing their TPT. Side effects were reported in 26 (39%) of the non-completion group. We conclude that high rates of TPT uptake and completion among contacts assessed as eligible for TPT can be achieved through person-centered care and the use of shorter regimens. Side-effect monitoring and management while on TPT is vital for improving TPT completion.
Genomic Analysis of Lymphoma Risk in Bullmastiff Dogs
Authors: Mortlock Sally A. , Asada Monica C. , Soh Pamela Xing Yi , Hsu Wei-Tse , Lee Carol , Bennett Peter F. , Taylor Rosanne M. , Khatkar Mehar S. , Williamson Peter
Published: December 2023

Lymphoma is the most common haematological malignancy affecting dogs and has a high incidence in the Bullmastiff breed. The aim of this study was to identify risk loci predisposing this breed to the disease. The average age of lymphoma diagnosis in 55 cases was less than 6 years, similar to the median age of 64 cases from our clinical and pathology databases. When fine-scale population structure was explored using NETVIEW, cases were distributed throughout an extended pedigree. When genotyped cases (n = 49) and dogs from the control group (n = 281) were compared in a genome-wide association analysis of lymphoma risk, the most prominent associated regions were detected on CFA13 and CFA33. The top SNPs in a 5.4 Mb region on CFA13 were significant at a chromosome-wide level, and the region was fine-mapped to ~1.2 Mb (CFA13: 25.2–26.4 Mb; CanFam3.1) with four potential functional candidates, including the MYC proto-oncogene bHLH transcription factor (MYC) and a region syntenic with the human and mouse lncRNA Pvt1 oncogene (PVT1). A 380 Kb associated region at CFA33: 7.7–8.1 Mb contained the coding sequence for SUMO specific peptidase7 (SENP7) and NFK inhibitor zeta (NFKBIZ) genes. These genes have annotations related to cancer, amongst others, and both have functional links to MYC regulation. Genomic signatures identified in lymphoma cases suggest that increased risk contributed by the regions identified by GWAS may complement a complex predisposing genetic background.
A Quantitative Approach for Identifying Nitrogen Sources in Complex Yeongsan River Watershed, Republic of Korea, Based on Dual Nitrogen Isotope Ratios and Hydrological Model
Authors: Hong Seoyeon , Han Youngun , Kim Jihae , Lim Bo Ra , Park Si-Young , Choi Heeju , Park Mi Rae , Kim Eunmi , Lee Soohyung , Huh Yujeong , Kim Kyunghyun , Lee Won-Seok , Kang Taewoo , Kim Min-Seob
Published: December 2023

Effective management of nitrate loading in complex river systems requires quantitative estimation to trace different nitrogen sources. This study aims to validate an integrated framework using soluble nitrogen isotope ratios (δ15N–NH4 and δ15N–NO3) and hydrological modeling (hydrological simulation program SPARROW) of the main stream and tributaries in the Yeongsan River to determine anthropogenic nitrogen fluxes among different land-use types in the complex river watershed. The δ15N–NH4 and δ15N–NO3 isotopic compositions varied across different land-use types (4.9 to 15.5‰ for δ15N–NH4 and −4.9 to 12.1‰ for δ15N–NO3), reflecting the different sources of nitrogen in the watershed (soil N including synthetic fertilizer N, manure N, and sewage treatment plant effluent N). We compared the soluble nitrogen isotopic compositions (δ15N–NH4 and δ15N–NO3) of the river water with various nitrogen sources (soil N, manure N, and sewage N) to assess their contribution, revealing that N from sewage treatment plant effluent as a point source was dominant during the dry season and N from forest- and soil-derived non-point sources was dominant due to intensive rainfall during the wet season. The coefficient of determination (R2) between the measured pollution load and the predicted pollution load calculated by the SPARROW model was 0.95, indicating a high correlation. In addition, the EMMA-based nitrogen contributions compared to the SPARROW-based nitrogen fluxes were similar to each other, indicating that large amounts of forest- and soil-derived N may be transported to the Yeongsan River watershed as non-point sources, along with the effect of sewage treatment plant effluent N as a point source. This study provides valuable insights for the formulation of management policies to control nitrogen inputs from point and non-point sources across different land-use types for the restoration of water quality and aquatic ecosystems in complex river systems. Given the recent escalation in human activity near aquatic environments, this framework is effective in estimating the quantitative contribution of individual anthropogenic nitrogen sources transported along riverine systems.
Classification of Breast Cancer using Ensemble Filter Feature Selection with Triplet Attention Based Efficient Net Classifier
Authors: Bangalore Nagaraj Madhukar , Shivanandamurthy Hiremath Bharathi , Matta Polnaya Ashwin
Published: December 2023

In medical imaging, the effective detection and classification of Breast Cancer (BC) is a current research important task because of the still existing difficulty to distinguish abnormalities from normal breast tissues due to their subtle appearance and ambiguous margins and distinguish abnormalities from the normal breast. Moreover, BC detection based on an automated detection model is needed, because manual diagnosis faces problems due to cost and shortage of skilled manpower, and also takes a very long time. Using deep learning and ensemble feature selection techniques, in this paper, a novel framework is introduced for classifying BC from histopathology images. The five primary steps of the suggested framework are as follows: 1) to make the largest original dataset and then deep learning model with data augmentation to improve the learning. 2) The best features are selected by an Ensemble Filter Feature selection Method (EFFM) which combines the best feature subsets to produce the final feature subsets. 3) Then the pruned Convolution Neural Network (CNN) model is utilized to extract the optimal features. 4) Finally, the classification is done through the Triplet Attention based Efficient Network (TAENet) classifier. The suggested model produces a 98% accuracy rate after being trained and tested on two different histopathology imaging datasets including images from four different data cohorts. Subsequently, the suggested strategy outperforms the conventional ones since the ensemble filter habitually acquires the best features, and experimental results demonstrate the importance of the proposed approach
EL ENFOQUE TOTALIZADOR EN LOS EDUCADORES DEL SIGLO XXI
Authors: Márquez Rodríguez Aleida
Published: December 2023

Las  aceleradas y crecientes complejidades en las que estamos inmersos, en la era de las  sociedades del conocimiento y de la información,   en los órdenes científico-técnico, político, económico, social, ambiental,   cultural, le plantean al profesional de la educación la necesidad de elevar su preparación pedagógica, psicológica, sociológica, ideológica,  ética, entre otras, para atender la diversidad de problemáticas e imprevistas contingencias, que emergen  en su significativa labor cotidiana. En el trabajo se presenta una sistematización como resultado de investigaciones realizadas y aplicadas  durante más de cuatro décadas,  se muestra el tránsito de un enfoque analítico hacia un enfoque totalizador  en las concepciones epistemológicas, se fundamenta un nuevo estilo de pensamiento holístico complejo, interdisciplinar y transdisciplinar cuyos  aportes  teóricos y metodológicos contribuyen a actualizar y elevar la eficiencia de la actividad pedagógica profesional de los educadores, acordes con las actuales y futuras exigencias profesionales y sociales de este nuevo siglo.
GUÍA DE APRENDIZAJE CON PROYECCIÓN HACIA EL DESARROLLO SOSTENIBLE: RETOS PARA LOS COLECTIVOS DE CARRERAS
Authors: Acosta Santana Daniel Augusto , Guillot Mustelier Leticia , Borrás Pérez Denis
Published: December 2023

El trabajo tiene como finalidad divulgar las recomendaciones didáctico – metodológicas tenidas en cuenta en la elaboración de las guías de aprendizaje de las asignaturas en la carrera Licenciatura en Educación. Matemática de la Universidad de Oriente (UO), para la autogestión del conocimiento por  los estudiantes, las cuales contribuyeron al desarrollo de habilidades profesionales necesarias para hacer frente a los retos del presente y el futuro tales como: analizar, interpretar, procesar, discernir y sintetizar informaciones, tomar decisiones, fomentar un pensamiento crítico y creativo, comunicar sus puntos de vista, gestionar estrategias de solución para los problemas y formular nuevos problemas, emplear las tecnologías de la información y las comunicaciones, autoevaluarse, entre otras, siendo necesarias para contribuir, como profesionales, a su sostenibilidad. Este resultado científico, fruto de un estudio científico – metodológico realizado por el colectivo de docentes, contribuyó a mejorar la proyección del proceso de enseñanza – aprendizaje, con miras al objetivo 4 de la Agenda 2030: Garantizar una educación inclusiva y equitativa de calidad y promover oportunidades de aprendizaje permanente para todos.
HABILIDADES PROFESIONALES PSICOPEDAGÓGICAS PARA LA ATENCIÓN AL DESARROLLO LOCAL DESDE LA FUNCIÓN ORIENTADORA DEL PSICOPEDAGOGO
Authors: Rodríguez González Arianne , Aranda Cintra Belkis , Portuondo Maurelo Yamilia
Published: December 2023

El presente artículo tiene como objetivo la elaboración de una metodología para el desarrollo de habilidades profesionales psicopedagógicas en los estudiantes de la carrera Pedagogía Psicología que posibilite la atención al desarrollo local como contenido de su función orientadora desde la asignatura Orientación Comunitaria. Su importancia radica en que se aborda una problemática actual en la cual  se connota la función orientadora del psicopedagogo y su incidencia en el desarrollo local de la comunidad como contexto de su actuación profesional, que adquiere en este futuro profesional matices especiales en correspondencia con su encargo social vinculado con la orientación educativa, la asesoría  psicopedagógica, la dirección del proceso de enseñanza-aprendizaje de las disciplinas pedagógicas y psicológicas y la investigación educativa en los contextos donde desarrolla su labor profesional.
Fundamentación Epistemológica de la Superación Profesional del Tecnólogo en Bioanálisis Clínico
Authors: Aties López Leonor , Burgal Cintra Carmen Juana , Antúnez Coca José
Published: December 2023

La superación profesional   en la carrera Bioanálisis Clínico no ha ocupado la importancia que realmente merece, por ser esta carrera diseñada solo unos pocos años. Sin embargo, el tecnólogo egresado constituye un recurso humano con formación especializada en determinada área del conocimiento humano. Por lo que se  realiza un análisis crítico  sobre  la  superación profesional  de los tecnólogos egresados de la carrera Bioanálisis Clínico, relacionada con las habilidades teórico-asistenciales para el diagnóstico de la resistencia antimicrobiana, es el objetivo de los autores diseñar  un proceso de superación profesional que se vincule con el desempeño profesional de los recursos humanos,  lo que conlleva en su relación al mejoramiento del desempeño profesional de los tecnólogos en Bioanálisis Clínico, que permita desarrollar, fomentar, potenciar  y fortalecer  estas habilidades para  optimizar la terapia antimicrobiana y así poder tomar las medidas requeridas para la contención de la resistencia antimicrobiana.
La motivación de colaboradores: esencial para la eficiencia productiva
Authors: Miravet Rodríguez David , Rodríguez Cosme María Luz
Published: December 2023

La motivación como categoría psicológica resulta vital para el logro de resultados superiores en cualquiera de las aristas sociales y mucho más en la calidad de la producción o los servicios de cualquier empresa o entidad laboral. Sin embargo, en ocasiones se ve afectada por disímiles causas que inciden en el cumplimiento de los objetivos productivos o estratégicos. De modo que el objetivo de esta investigación es: desarrollar un conjunto de acciones a través de una estrategia de dirección administrativa, para elevar la motivación por el trabajo y el logro de resultados superiores en la producción de los servicios a la sociedad. Para la realización de esta investigación se tuvieron en cuenta variados métodos como la entrevista, encuesta que posibilitaron conocer las debilidades de la empresa y por ende, la actitud ante el trabajo de los obreros. La implementación parcial de estas acciones ha permitido el logro de mejores resultados y una adecuada motivación de los obreros, a pesar de las dificultades con la materia prima para la producción de diversos medicamentos en estos dos últimos años.
Analfabetismo motor e suas implicações no desenvolvimento das habilidades motoras durante a fase educacional
Authors: Carneiro Luiz Henrique Magalhães , Benjamim Caio Santiago
Published: December 2023

O analfabetismo motor é uma condição que se caracteriza pela dificuldade ou incapacidade de realizar movimentos básicos e coordenados com o corpo. É um fenômeno pouco estudado, mas que afeta a vida de muitas pessoas ao redor do mundo. As causas do analfabetismo motor podem ser variadas, incluindo fatores neurológicos, como lesões cerebrais, distúrbios do desenvolvimento, paralisia cerebral e condições genéticas. Outros fatores, como falta de estimulação e oportunidades adequadas de aprendizado motor, também podem contribuir para o desenvolvimento dessa condição. As consequências do analfabetismo motor podem ser significativas. Indivíduos que apresentam dificuldades motoras podem ter dificuldade em realizar tarefas básicas do dia a dia, como amarrar os sapatos, usar talheres, vestir-se, escrever e praticar esportes. Essas limitações podem afetar sua independência, autoestima e inclusão social, além de impactar seu desempenho acadêmico e profissional. A pesquisa sobre o analfabetismo motor é justificada pela sua relevância nos âmbitos social, educacional e de saúde pública. O objetivo central desta pesquisa é aprofundar a compreensão do analfabetismo motor, explorando suas origens, implicações e possíveis estratégias de intervenção.
Decolonizar a educação física escolar indígena: uma ação urgente na revitalização das brincadeiras, jogos e atividades indígenas
Authors: Cavalcante Gardênia Maria Barbosa , De Macêdo Letycia Alves , De Matos Maristela Bortolon
Published: December 2023

O debate acerca da relação entre o corpo e a Educação Física Escolar Indígena é uma temática que vem sendo amplamente abordada. Logo, o objetivo desta pesquisa foi entender a relação dos corpos com a educação física escolar indígena. Para tanto, a questão problematizadora consistiu em responder: em que medida as práticas e as relações corporais contribuem com a educação física escolar indígena? A pesquisa teve como direcionamento metodológico a abordagem qualitativa, embasando-se na pesquisa bibliográfica e no estudo de caso. Em síntese, a Educação Física Escolar Indígena se constitui enquanto componente curricular, tornando-se uma manifestação social e cultural, que se propaga por meio das práticas corporais a voz dos povos originários.