bluuebunny/crossref_metadata_2025 huggingface dataset:
Colitis can be Improved by (−)-Epigallocatechin Gallate through Targeting Notch in DSS-induced UC mice
Authors: yang xiaoying , Li Jian-Fei , Wang Yuan-Zhu , li Ming-Ming , chen ke , Wang Xuan-jun , Sheng Jun , Zhu Qiang-Qiang
Published: March 2024

Abstract Background: Ulcerative colitis (UC) is a chronic and
non-specific inflammatory bowel disease. Previous research shows that
Notch plays a role in the pathogenesis of UC and (−)-Epigallocatechin
Gallate(EGCG) could attenuate colitis. However, the mechanism of EGCG to
improve colitis remains unclear. Methods:The human epithelial colorectal
adenocarcinoma Caco-2 cells were intervened with EGCG (10ug/ml or
30ug/ml) with or without Lipopolysaccharide. A mouse model of UC was
induced by 3% dextran sulfate sodium and EGCG treatment was
administered to mice at a dose of 10 and 20 mg/kg. The stool
consistency, rectal bleeding and weight were recorded daily. The disease
activity index (DAI) of mice was calculated, and the pathological injury
scores were assessed through hematoxylin and eosin staining.
Immunohistochemical analyses were performed for iNOS, F4/80, Notch1 and
hes1. Inflammatory cytokines were detected using ELISA kits .Western
blot assays were performed for TNF-α, IL-1β, , Notch1, Cleaved-Notch1,
Notch2,, Hes-1, COX2, iNOS from colon tissues and Caco-2 cells. Results:
In this study, we found that the cytokine secretion and inflammation
protein expression were reduced with EGCG treatment in LPS induced
Caco-2 cells. And the levels of Notch1, Cleaved-Notch1, and Hes-1
expression were decreased by EGCG administration in the cell. Moreover,
we found the pro-inflammation cytokine secretion and the macrophages
accumulation were reduced by oral EGCG in DSS-induced mice colon which
indicates EGCG ameliorates colitis in vivo. And we also found the
phenotype of macrophages could alter to M1 was inhibited by oral EGCG in
vivo. In addition, we demonstrate that EGCG could attenuate the levels
of Notch1, Cleaved-Notch1, and Hes-1 expression in the colon.
Conclusion: This study demonstrates that colitis can be improved by EGCG
through targeting Notch in DSS-induced UC mice. Key words: EGCG; Notch;
colitis; inflammation
The public health impact of suspending cyproterone acetate/ ethinylestradiol (Diane-35 and generics) in France: A predictive modelling technique
Authors: Bobbins Amy , Lane Samantha , Lynn Elizabeth , Shakir Saad
Published: March 2024

Purpose: To predict the public health impact of marketing
authorisation suspension of cyproterone acetate/ ethinylestradiol
(Diane-35 and its generics) in France using a novel modelling technique,
and to critique the model. Methods: Cyproterone acetate/
ethinylestradiol exposures in primary care were estimated using IQVIA’s
IMS-France electronic health records database. Systematic review
identified quantitative research with event data for exposed
participants. The main outcome measure was prevented thromboembolic
events as a result of marketing authorisation suspension.
Results: At the time of marketing authorisation suspension,
4,325,863 active female patients of childbearing potential (aged 10-49
years) were in the IMS-France database. Between 12 months pre- and 12
months post-suspension, average monthly exposure to Diane-35 and its
generics decreased by 78.79%, from 8.49 to 1.80 per 100,000 female
patients aged 10-49 years. Absolute risk, calculated from event data
from three observational studies, was estimated at 53.9%. Approximately
147 cases of thromboembolism would be prevented as a result of the
eight-month suspension within exposed IMS-France patients (female, aged
10-49 years). A sensitivity analysis with risk estimates from the
Summary of Product Characteristics suggested that less than one case
would be prevented during the eight-month suspension.
Conclusions: The predictive modelling technique is heavily
reliant on the accuracy of utilisation and absolute risk data, as the
risk of thromboembolic events differed when event data was estimated
from published research or the Summary of Product Characteristics.
Nonetheless, this model has wide applicability in other settings where a
measurable change in drug utilisation may be obtained, such as
withdrawal of marketing authorisation or restriction of prescribing.
Neuroprotective effects of resveratrol on retinal ganglion cells in glaucoma: Focusing on oxidative stress, cellular, and molecular mechanisms
Authors: Zamanian Mohammad , Golmohammadi Maryam , Meibodi Seyed Arash Aghaei , Al-Hawary Sulieman Ibraheem Shelash , Gupta Jitendra , Sapaev Ibrohim B. , Najm Mazin A.A. , Alwave Marim , Nazifi Mozhgan , Rahmani Mohammadreza
Published: March 2024

Retinal ganglion cells (RGCs) are the major cells that are damaged in
glaucoma leading to vision loss and blindness. The damage to RGCs in
glaucoma is caused by various mechanisms such as elevated intraocular
pressure, oxidative stress, inflammation, and other neurodegenerative
processes. As the disease progresses, more and more RGCs are lost,
leading to a gradual loss of vision. Therefore, protecting RGCs from
damage and promoting their survival is an important goal in the
treatment of glaucoma. Resveratrol (RES) exerts anti-oxidant effects and
slows down the evolution and progression of glaucoma. This review was
prepared using databases such as Google Scholar, PubMed, Scopus, and
ScienceDirect. Based on the findings of this review, RES has a
protective role on RGCs in cases of ischemic injury and hypoxia as well
as ErbB2 protein expression in the retina. Additionally, RES has
protective effects on RGCs by promoting cell growth, reducing apoptosis,
and decreasing oxidative stress in H2O2-exposed RGCs. RES was also found
to inhibit oxidative stress damage in RGCs and suppress the activation
of MAPK signaling pathways. Moreover, RES could alleviate retinal
function impairment by suppressing the HIF-1a/VEGF and p38/p53 axis
while stimulating the PI3K/Akt pathway. Hence, RES might exert potential
therapeutic effects in the treatment of glaucoma by protecting RGCs from
damage and promoting their survival.
Some existence results for the generalized tensor absolute value equation
Authors: Sharma Sonali , Palpandi K.
Published: March 2024

This paper introduces a new type of tensor absolute value equation, namely
the generalized tensor absolute value equation (GTAVE), and studies its
equivalence to the generalized tensor complementarity problem (GTCP).With
the help of this equivalence and the degree theory approach, some existence
results for the GTAVE are achieved.
Minimal cusco maps and the topology of uniform convergence on compacta
Authors: Holá Ľubica , Holý Dusan
Published: March 2024

Minimal cusco maps have applications in functional analysis, in optimization,
in the study of weak Asplund spaces, in the study of differentiability of
functions, etc. It is important to know their topological properties. Let X
be a Hausdorff topological space, MC(X) be the space of minimal cusco maps
with values in R and ?UC be the topology of uniform convergence on compacta.
We study completemetrizability and cardinal invariants of (MC(X), ?UC). We
prove that for two nondiscrete locally compact second countable spaces X and
Y, (MC(X), ?UC) and (MC(Y), ?UC) are homeomorphic and they are homeomorphic
to the space C(Ic) of continuous real-valued functions on Ic with the
topology of uniform convergence.
On torse-forming vector fields and their applications in submanifold theory
Authors: Sarkar Avijit , De Uday , Halder Suparna
Published: March 2024

The present article utilises a property of torse-forming vector fields to
deduce some criteria for invariant submanifolds of Riemannian manifolds to
be totally geodesic. Certain features of submanifolds of Riemannian
manifolds as ?-Ricci Bourguignon soliton have been developed.
An algorithmic approach for a class of set-valued variational inclusion problems
Authors: Balooee Javad , Yao Jen-Chih
Published: March 2024

The main goal of this paper is twofold. Our first objective is to prove the
Lipschitz continuity of the proximal-point mapping associated with an
H-accretive operator and to compute an estimate of its Lipschitz constant
under some new appropriate conditions imposed on the parameter and mappings
involved in it. Using the notion of proximal-point mapping, a new iterative
algorithm is constructed for solving a new class of set-valued variational
inclusion problems in the setting of q-uniformly smooth Banach spaces. As an
application, the strong convergence of the sequences generated by our
proposed iterative algorithm to a solution of our considered problem is
proved. The second objective of this paper is to investigate and analyze the
notion of ??-H((.,.), (.,.))-mixed accretive mapping introduced and
studied in [S. Gupta, S. Husain, V.N. Mishra, Variational inclusion governed
by ??-H((.,.), (.,.))-mixed accretive mapping, Filomat 31(20)(2017)
6529-6542]. Some comments concerning ??-H((., .), (., .))-mixed accretive
mapping and related conclusions appeared in the above-mentioned paper are
also pointed out.
Complete convergence for weighted sums of widely negative dependent random variables under the sub-linear expectations
Authors: Liu Chang , Yin Qing
Published: March 2024

In the paper, the complete convergence for weighted sums of arrays of rowwise
widely negative dependent random variables under the sub-linear expectations
is established. The main result partially extend some known results both in
the classical probability space and sub-linear expectation space. In
addition, it weaken their conditions.
Patients experience with the use of a penile clamp in post-prostatectomy incontinence – a prospective pilot study
Authors: Jula Alexandru , Andreasson Anders , Logadottir Yr , Olsen Ekerhult Teresa
Published: March 2024

Objectives: The aim of this study was to assess the efficacy of a penile clamp in managing urinary incontinence (UI) and its impact on perceived quality of life (QoL) amongst post-prostatectomy patients.
Material and methods: A prospective pilot study was conducted including patients with post-prostatectomy UI treated with a penile clamp. Inclusion criteria consisted of UI after radical prostatectomy, good hand function, full cognitive function and a minimum penile length of 3 cm and a circumference of 5 cm. An appropriately sized penile clamp was selected during the first visit, and patients were given instructions on how to use it. The first follow-up was a scheduled phone call 1 week after the initial visit. Formal evaluations were performed prior to use of the penile clamp and again after 3 months of usage. These consisted of weighing pads during the daytime with evaluation of leakage, International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF), incontinence-QoL (I-QoL) and a questionnaire specific for the penile clamp.
Results: There were 22 patients included, and two were excluded due to reduced hand function and surgery before the study endpoint. The results showed a significant median reduction of urinary leakage of 57% at rest and 58% during physical activity. One complication was observed, as one patient developed a pinching ulcer, after extensive usage. ICIQ-SF showed an increase of 6% for the included patients (n = 20). Ten patients were satisfied with the clamp, and 15 would recommend the clamp to others.
Conclusion: The penile clamp shows promising results in reducing leakage with minimal risks of complications. It can be used as a treatment for patients awaiting surgery. However, patient selection is important regarding hand function, cognitive function and the penile anatomy.
STRESS AND EMOTION MANAGEMENT AS THE KEY TO SUCCESS FOR MSME OWNERS
Authors: Ash-shiddiqy Muhammad
Published: March 2024

This research is motivated by the awareness of the importance of stress and emotion management in the success of small and medium-sized enterprises (SMEs). The aim of this study is to provide a better understanding of the significance of stress and emotion management for SME owners and to assist in implementing stress and emotion management techniques. The research conducted is qualitative research using the ABCD method. The subjects of this study are SME owners in Selogiri Village, Kebumen. Data collection techniques were carried out through interview observations. The results of this study indicate that stress management has a significant impact on SME practitioners in developing their products. Based on the data obtained, SME practitioners in Selogiri Village mentioned that stress arises from comments made by some consumers. Their approach to managing stress is to evaluate their products based on the comments given by consumers, so they believe that improving the quality of their products can silence consumers with negative comments. Stress management in this context means turning hate comments into product evaluation materials for SME practitioners.
Exploration of Shariah Non-Compliant Risk: Evidence from Indonesia
Authors: Ma'ruf Aminudin , Wulandari Asih Putri
Published: March 2024

Sharia non-compliance is a peculiar risk that Islamic financial institutions must face. This study aims to explore and analyse the presence of Sharia non-compliant risk in Indonesia. The method used in this study is a descriptive normative legal research method with a qualitative approach, using related literature books and journals. The study's data was obtained from religious courts in Indonesia and Sharia committee data from the annual reports of Indonesian Islamic banks. The study results concluded that some Sharia non-compliance risk cases in Indonesia need serious attention from the Islamic financial industry. The Sharia non-compliance cases are dominated by default in Shariah. Therefore, the study urges maximization of the role of the Sharia committee and the development of the nation's literacy of Islamic economics and finance. The study comes with recommendations for policymakers and carries some limitations for future studies in Shariah non-compliant risk.
PENGEMBANGAN BAHAN AJAR SENAM RITMIK BERBASIS DIGITAL DI UNIVERSITAS SAMUDRA
Authors: Fitria Fitria , Roberto Julio , Syahputra Muhajjir , Kurniawan Rizkei , Aprial. M Benny
Published: March 2024

Keberadaan bahan ajar untuk materi senam ritmik di tingkat perguruan tinggi Universitas Samudra sudah tersedia dengan baik hanya saja, belum tersedia nya petunjuk tutorial pelaksanaan per materi ajar yang berbasis digital dalam bentuk video youtube. Bahan ajar senam ritmik yang selama ini hanya meliputi tampilan gambar-gambar yang ada di buku dan memakai musik senam pada umumnya tidak terkhusus dalam materi ajar. Dalam hal ini tentunya menyulitkan mahasiswa dalam memahami materi perkuliahan sehingga tidak tercapai dengan maksimal kemampuan motoriknya dan pembelajaran yang sesuai dengan Merdeka Belajar Kampus Merdeka tahun 2023.  Penelitian ini bertujuan untuk menghasilkan bahan ajar senam ritmik berbasis digital di Universitas Samudra. Penelitian ini merupakan penelitian Research and Development (R&D) dengan model pengembangan ADDIE. Subjek penelitian ini berjumlah 58 mahasiswa program studi Pendidikan Jasmani. Teknik analisis data dilakukan dengan cara deskriptif kuantitatif. Hasil penelitian diketahui bahwa: (1) penilaian oleh ahli meliputi substansi aspek materi dan aspek desain pembelajaran dikategorikan “Sangat Layak” dengan presentase nilai 82,97%. (2) penilaian materi oleh dosen sebagai user meliputi substansi aspek materi dan aspek desain pembelajaran dikategorikan “Sangat Layak” dengan presentase nilai sebesar 87,82%. (3) penilaian respon peserta didik yaitu The Computer System Usability meliputi aspek kegunaan, kualitas informasi, dan kualitas tampilan video dikategorikan “Sangat Layak” dengan presentase nilai sebesar “82,92%”.
EFEKTIFITAS PEMBELAJARAN MODEL ADVANCE ORGANIZER DENGAN MEDIA INTERNET TERHADAP HASIL BELAJAR DAN KARAKTER KEMANDIRIAN SISWA
Authors: Nasution Mutiara Agustina , Sari Dwy Puspita , Putri Intan Permata , Perdana Simanjuntak Yanthy Leonita
Published: March 2024

Tujuan penelitian untuk mengetahui bagaimana efektifitas model pembelajaran advance organizer dengan media internet terhadap hasil belajar dan tingkat kemandirian siswa. Jenis penelitian adalah quasi eksperimen. Populasi penelitian ini adalah siswa kelas XI IPA di MAN 3 Medan. Tiga kelas eksperimen yaitu X1, X2 dan X3 sebagai sampel melalui teknik random sampling, masing-masing 27 orang siswa. X1 adalah kelas dengan pembelajaran model direct instruction, X2 diberi  pembelajaran advance organizer dan media internet  dan X3 diberi  pembelajaran model pembelajaran advance organizer tanpa media. Untuk mengukur hasil belajar digunakan instrument tes, sedang instrument non-tes digunakan dalam pengukuran karakter kemandirian. Dengan Uji ANOVA One Way, didapati rata-rata hasil belajar kelas X1, X2 dan X3 berturut sebesar 68.44, 72.26, dan 72.04 serta hasil karakter kemandirian siswa sebesar 36.22, 38.48, dan 35.96. Dari data didapat bahwa kelas dengan nilai rata-rata hasil belajar dan karakter kemandirian yang paling tinggi adalah kelas X2. Nilai signifikansi uji ANOVA One Way sebesar 0,016 untuk hasil belajar dan 0,019 untuk karakter kemandirian, ini membuktikan pengaruh variasi model pembelajaran terhadap hasil belajar juga karakter kemandirian siswa. Dari hasil uji korelasi antara hasil belajar dan kemandirian didapat nilai sig. 0.011, ini memperlihatkan ada hubungan yang signifikan antara hasil belajar dan karakter kemandirian siswa.
PENGARUH MODUL KOLOID BERBASIS CHEMOENTREPRENEURSHIP (CEP) TERHADAP HASIL BELAJAR SISWA SMA
Authors: Sari Dwy Puspita , Nasution Hafni Indriati , Nasution Mutiara Agutina , Arwita Widya , Naelofaria Salmah , Sinaga Lastama
Published: March 2024

Tujuan dari penelitian ini untuk mengetahui pengaruh modul koloid berorientasi chemoentrepreneurship terhadap hasil belajar siswa kelas XI SMA Negeri 2 Medan. Jenis penelitian ini menggunakan kelompok kontrol non-ekuivalen dan desain penelitian kuasi eksperimen. Dua kelas XI IPA SMA Negeri 2 Medan dijadikan sebagai subjek penelitian dan sampel diambil secara acak. Uji N-gain dan uji kesamaan dua rata-rata (uji-t) digunakan untuk menganalisis data. Perolehan rata-rata pretest kelas eksperimen adalah 39,72, sedangkan kelompok kontrol adalah 39,03. Perolehan rata-rata posttest untuk kelas eksperimen adalah 83,19, sedangkan untuk kelas kontrol adalah 77,64. Hasil uji-t diperoleh thitung>ttabel (3,74>2,34), yang menunjukkan bahwa Ho ditolak dan Ha diterima. Hasil uji n-gain untuk kelas eksperimen sebesar 71%, sedangkan untuk kelas kontrol sebesar 59%. Hal ini menunjukan bahwa modul koloid berbasis chemoentrepreneurship efektif digunakan untuk meningkatkan pemahaman dan ketertarikan dalam proses pembelajaran.
KEEFEKTIFAN KOMIK DIGITAL DALAM MENINGKATKAN MINAT BELAJAR DALAM PEMBELAJARAN IPA SISWA KELAS IV SEKOLAH DASAR
Authors: Arfika Nurul , Yeni Purba Fince Putri , Adillah Rani , Gurning Biworo Frida , Silaban Saronom
Published: March 2024

Kajian ini berlandaskan dengan dari situasi pendidikan di sekolah dasar yang masih minim akan perubahan dalam pemberian materi secara digital. Selain itu, kurangnya variasi tersebut membuat siswa kurang tertarik dan tidak mau ikut andil dalam belajar. Kajian ini bermaksud memaparkan keefektifan komik digital dalam meningkatkan minat siswa dalam belajar IPA. Dengan kajian yang digunakan adalah kuantitatif. Kajian dilakukan di SDN 060834 Medan dengan siswa kelas VI sebanyak 25 siswa sebagai subyek kajian, dengan data yang dikumpulkan berasal dari observasi, wawancara dan angket. Dan selanjutnya data  itu dianalisis melalui deskriptif kuantitatif yang bermakna memaparkan hasil peningkatan minat belajar siswa yang didapat dari sebaran angket sebelum dan setelah diterapkannya komik digital dalam belajar  IPA. Hasil kajian memaparkan dengan diterapkannya komik digital minat siswa menjadi meningkat, terbukti peningkatan sebanyak 43% dari  sebelum dengan komik digital minat siswa hanya 47% capaian kurang baik dan kini setelah diterapkan komik digital menjadi 90%  capaian sangat baik. Sehingga dikonklusikan komik digital yang diterapkan dalam belajar IPA memiliki keefektifan yang sangat tinggi dalam meningkatan minat belajar siswa sekolah dasar.
Diagnóstico del futuro de la empresa familiar a partir del estudio de los fundadores de empresas familiares y el análisis de la evolución de las estructuras familiares y el tejido empresarial en España
Authors: Doral-Fábregas Fernando
Published: March 2024

El objetivo de este estudio es diagnosticar si la empresa familiar será un fenómeno creciente o decreciente dentro del tejido empresarial. Para ello, se tomó una muestra de 50 empresas familiares españolas de diversos sectores, la cual permitió identificar distintos factores relacionados con la persona que fundó la empresa, tales como el apoyo recibido por parte de su familia, la edad al fundarla o el número de hijos. Con la información obtenida se llevó a cabo una técnica de clustering para identificar agrupaciones. Esa caracterización se tomó como base para identificar tres factores que deben ser analizados: las estructuras familiares, el tejido empresarial y las motivaciones de los empresarios. La evolución de estos factores, analizados mediante métodos de regresión lineal, parece hablar en contra del surgimiento de empresas familiares, por lo que se diagnostica que la empresa familiar es un fenómeno en tendencia decreciente.
Area esterna dell’edificio medievale inferiore (SAS 1). Il fronte nord-occidentale dell’altura di q. 542 prima del Medioevo
Authors: Corretti Alessandro , Vaggioli Maria Adelaide
Published: March 2024

Le indagini del 2022 hanno ampliato notevolmente la visione architettonica e funzionale del complesso sacro lungo il fianco nord-occidentale della q. 542. A nord, nei pressi di una cava di gesso, un edificio assiale a tre vani fu in uso fino alla fine del IV/inizio del III secolo a.C. Sugli strati detritici, una nuova frequentazione ebbe luogo tra la fine del III e il II secolo a.C. Sul lato meridionale, un grande spazio scoperto fiancheggiava questo edificio e, dopo un piccolo ambiente trapezoidale con un diverso orientamento, che seguiva il pendio della collina, una grande stanza mostrava una fila di piccole cavità nel terreno. Due cavità contenevano offerte votive intatte, tra cui una statuetta raffigurante Atena. Un incendio distrusse questo edificio tra la fine del IV e l'inizio del III secolo a.C.
The responsibility of corporate actors involved in international crimes through autonomous weapons systems (AWS) before the international criminal court (ICC)
Authors: Baroudy Jinane EL
Published: March 2024

The use of autonomous weapons systems (AWS) has led to several opposing legal opinions regarding their violations of international law. The responsibility of the state, individuals, and corporations as producers, designers, and programmers is all being taken into consideration. If the decision to kill humans without “meaningful human control” is transferred to computers, it would be hard to attribute accountability for the actions of AWS to their corporations. Consequently, this means that corporate actors will enjoy impunity in all cases. The present paper indicates that the most significant problem arising from the use of AWS is the attribution of responsibility for its violation. Corporations are not subject to liability for the legitimate use of weapons under international law. The main problem with corporate responsibility, according to article 25 (4) of the Rome Statute, is that the provision only relates to individual criminal responsibility and that the ICC shall only have jurisdiction over natural persons. Nevertheless, corporations may be held accountable under aspects of international law. The paper proposes a more positive view on artificial intelligence, raising corporations’ accountability in international law by historically linking the judging of business leaders. The article identifies aiding and abetting as well as co-perpetration as the two modes of accountability under international law potentially linked to AWS. The study also explores the main ambiguity in international law relating to corporate aiding and abetting of human rights violations by presenting the confusion on determining the standards of these 2 modes of liability before the ICC and International ad doc Tribunal. Moreover, with the new age of war heavily dependent on AI and AWS, one cannot easily and precisely ascertain who must be held accountable for war crimes because of the unanticipated facts in decision-making combined with the aiding or abetting of violations of international law. International law prioritizes the goal of ending impunity for the individual and largely neglects the need to achieve the same goal for corporate complicity. In sum, progress to regulate the use of AWS by corporate actors could be enormously helpful to the cause of ending impunity.
Peganum Harmala L. plant as green non-toxic adsorbent for iron removal from water
Authors: Alsaiari Raiedhah , Shedaiwa Iman , Al-Qadri Fatima A. , Musa Esraa M. , Alqahtani Huda , Alkorbi Faeza , Alsaiari Norah A. , Mohamed Mervate M.
Published: March 2024

The present work focuses on examining the batch removal of Fe (III) from water using powdered Peganum Harmala seeds, characterized as FT-IR. In this work, several parameters are measured, including contact time, pH, Fe (III) concentration, reaction temperature effect, and adsorbent dose effect. Fe (III) adsorption was assessed using a UV-vis spectrophotometer at a wavelength of 620 nm. The findings demonstrated a positive correlation between the dosage of adsorbent and Fe (III) ions removal, with an increase in the adsorbent dose corresponding to higher elimination of Fe (III) ions. Therefore, the Langmuir isotherm model yielded more accurate equilibrium data compared to the Frendulich model. The kinetic data were mostly analyzed using a pseudo-second-order model rather than a pseudo-first-order model. Thermodynamic parameters, including enthalpy (ΔH◦), entropy (ΔS◦), and free energy (ΔG◦), were calculated. The adsorption process was found to be exothermic. Overall, Peganum Harmala was a favorable adsorbent for removing Fe (III) from aqueous solutions.
History of deforestation in the vicinity of a village in Northern Masovia, Poland: An example of the possible old wood effect
Authors: Zawadzka-Pawlewska Urszula , Smolska Ewa , Sobucki Mateusz
Published: March 2024

Anthropogenic activity changes the processes of erosion on slopes. The deforestation process is connected with the deposition of material at the foot of the slope. During this process, macro-charcoals from anthropogenic-induced fires are trapped in the sediments. This paper provides an analysis of charcoal counts and sediment characteristics and is supported by historical data analysis. During this study, a discrepancy between radiocarbon dating and historical data was revealed; a probable explanation is presented.
BONUS EPISODE: Making the Most of Psi Chi
Authors: Cannon Bradley
Published: March 2024

First, discover opportunities open to all, including nonmembers, that will help you connect with the field of psychology and become more familiar with Psi Chi. Second, find out who all is eligible to join Psi Chi so that you can take your experience to the next level. And third, explore some key membership benefits—including a few newer ones that might surprise even seasoned members.
ISO 37120 Indicators for Sustainable Cities: Brazil and Portugal
Authors: Stefani Silvio Roberto , Peixoto João Paulo Seara Sequeira do Vale , Santos Paula Cristina da Costa , Ferreira Reinaldo Manuel Lopes Dias , Chiusoli Cláudio Luiz , Rodrigues Cláudia Susana Ribeiro
Published: March 2024

Purpose: the main goal of the research is to analyze the ISO 37120 indicators in two cities located in Brazil and Portugal, verifying  whether  sustainable development strategies are present in public policies.
 
Design: This research fits in a quantitative methodology, making use of on-line survey. The units of analysis of this research are the municipalities of Guarapuava - Brazil and Matosinhos – Portugal, Cross-Country Comparative Research.
 
Findings: Through quantitative research, the citizens have presented a general perception about Education, Health, and Security indicators, sometimes in a positiveway, other times in a negative one. About the main objective, it was noticed that the the connection between the inquired citizens were the  related indicators (sectors). The results obtained show that the ISO 37120 indicators can assist in an integrated monitoring of city governance, and  function  as  advisory tool for  some specific goals to city improvement in many aspects.
 
Research implications: The research applied ISO indicators, which are very powerful to evaluate the public policies of cities.  Therefore, it contributed with a potential evaluative instrument that indicates the priority targets for investments and development of public actions. Given that, the research also developed important reflections that may benefit the governance and provision of effective public services in many areas, namely, decision making support, urban planning and cities master plans, and UN SDG 11.
APROXIMAÇÃO DOS CONCEITOS DE JUSTIÇA AMBIENTAL E ESPACIALIDADE À SALUBRIDADE AMBIENTAL
Authors: Oliveira Adeilson Moizés de , Gouvêa Josiane Barbosa , Barbado Norma
Published: March 2024

Objetivo: Discutir a relação entre a justiça ambiental, salubridade e espacialidade da cidade.
Método: O estudo caracteriza-se como um ensaio teórico que busca, de forma reflexiva, articular a intersecção existente entre os estratégicos e como atuar de forma estratégica na manutenção de cenários de desigualdade e opressão nas cidades.
Resultados e Conclusões: O aprofundamento teórico realizado demonstra que a espacialidade, o direito à cidade, a justiça ambiental e a salubridade ambiental estão intrinsecamente ligadas quando se trata de garantir um ambiente saudável e equitativo para todos. Portanto, garantir tal ambiente requer uma abordagem integrada desses conceitos, promovendo políticas e práticas que promovam a inclusão social, a justiça ambiental e o acesso igualitário aos recursos e serviços urbanos.
Implicações da pesquisa:  Esta pesquisa direciona um olhar crítico e reflexivo sobre as questões que permeiam a espacialidade da cidade, a distribuição da justiça ambiental e as implicações desses fatores no acesso a um ambiente salubre, democrático e socialmente justo.
Originalidade/valor: As discussões sobre a temática abordada ainda são bastante raras na literatura. Espera-se instigar o debate e ascender outras pesquisas sobre a inter-relação apontada compreendendo a rede complexa de relações que exige abordagens integradas para promover a sustentabilidade a partir de uma perspectiva mais holística das áreas urbanas.
Sonodegradation of Sulfamethoxazole in Water Using Red Mud and Rice Husk Biochar Catalysis
Authors: Thi Mai Nguyen , Van Thanh Dang , Manh Khai Nguyen , Thi Minh Hang Tran
Published: March 2024

This research evaluated the effectiveness of sulfamethoxazole (SMX) antibiotic degradation in aqueous solution using red mud and rice husk biochar (RMC) as catalytic material for ultrasound-supported degradation process. Transmission Electron Microscopy (TEM), X-ray diffraction (XRD), and Energy-dispersive X-ray spectroscopy (EDX) were applied to study the characteristics of the catalytic material. The results demonstrated that the main components of RMC catalytic material are C, O, Si, and Fe elements with high weight percentage of 26.56%, 50.89%, 1.86% and 10.26%, respectively, and with high crystallized mix ratio. These are beneficial for SMX degradation reactions in water under the effect of ultrasound irradiation. The SMX degradation products were analyzed using High-performance liquid chromatography (HPLC). The effect of pH, contact time, initial concentration, and catalyst weight on degradation effectiveness were also investigated. The highest degradation efficiency of 75% at the treated rate of 15 mg SMX/g RMC was observed at pH = 3, contact time of 180 minutes, initial concentration of 20 mg SMX/L. This suggested a new solution to utilize the waste resources for waste treatment.
A new species of the genus Phyllonorycter Hübner, 1822 (Lepidoptera: Gracillaridae) from Korea
Authors:   Department of Science Education, Gongju National University of Education, Woongjinro 27, Gongju-si, Chungnam 32553, Republic of Korea, Sohn J.-C.
Published: March 2024

A new species of Gracillariidae, Phyllonorycter wolaksana sp. n., is described on the basis of six specimens from Republic of Korea. External and genital features of the new species are illustrated. Holotype of the species is deposited in the Gongju National University of Education, Gongju, Korea.
Building a Photocatalyst Library of MR-TADF Compounds with Tuneable Excited-State Redox Potentials
Authors: Hämmerling Lea , Zysman-Colman Eli
Published: March 2024

Epitomised by 4CzIPN, donor-acceptor (D-A) thermally activated delayed fluorescence (TADF) compounds based on the carbazoyl dicyanobenzene have now become widely used as they are sustainable photocatalyst alternatives to organometallic complexes owing to their similar optoelectronic properties to many of the iridium-based photocatalysts. Multi-resonant TADF (MR-TADF) compounds offer distinct advantages over D-A TADF compounds as they have more intense low-energy absorption bands, offering faster reaction kinetics, and are less sensitive to the polarity of the environment, mitigating undesired energy loss that typically accompanies the CT excited states of the photocatalysts. Here we report the assessment of strongly photoreducing boron- and nitrogen-doped MR-TADF compounds DABNA-1, tDABNA, CzBN and DtBuCzB across a range of benchmark photochemical reactions. The structural differences between each member of this library of photocatalysts enables modulation of their ground- and excited-state redox potentials. These photocatalysts performed competitively compared to the literature-known 4CzIPN, Ph-PTZ and fac-Ir(ppy)3.
Enantioselective Oxidation of Benzylic C–H Bonds via Dual Photoredox and Copper Catalysis
Authors: Liu Xian-Ming , Li Fu , Dai Ling , Liu Jing-Yuan , Xiao Li-Jun , Zhou Qi-Lin
Published: March 2024

Directly asymmetric oxidation of C(sp3)–H bonds of organic molecules would radically alter current methods of synthesizing chiral alcohols and esters, which are widely existed in the structures of natural products, pharmaceuticals, and fine chemicals. The Kharasch–Sosnovsky reaction is commonly used process for oxidation of allylic C(sp3)–H bonds of alkenes to yield allyl esters. However, its asymmetric variant is limited to cycloalkenes, and the enantioselectivity and efficiency of the reactions of open-chain alkenes are low. Moreover, asymmetric Kharasch–Sosnovsky reactions of alkanes remain a seemingly insurmountable challenge. However, we herein report a method for highly enantioselective oxidation of benzylic C(sp3)–H bonds of arylalkanes by dual photoredox and copper catalysis. The method extends the scope of the Kharasch–Sosnovsky reaction to alkanes and, more importantly, uses alcohols or carboxylic acids instead of peroxides as oxygenated coupling partners. With this method, we obtained various chiral alcohols and esters with high enantioselectivity directly from readily available arylalkanes.
Accelerated screening of gas diffusion electrodes for carbon dioxide reduction
Authors: Jones Ryan , Lai Yungchieh , Guevarra Dan , Kan Kevin , Haber Joel , Gregoire John
Published: March 2024

The electrochemical conversion of carbon dioxide to chemicals and fuels is expected to be a key sustainability technology. Electrochemical carbon dioxide reduction technologies are challenged by several factors, including the limited solubility of carbon dioxide in aqueous electrolyte as well as the difficulty in utilizing polymer electrolytes. These considerations have driven systems designs to incorporate gas diffusion electrodes (GDEs) to bring the electrocatalyst in contact with both a gaseous reactant/product stream as well as a liquid electrolyte. GDE optimization typically results from manual tuning by select experts. Automated preparation and operation of GDE cells could be a watershed for the systematic study of, and ultimately the development of a materials acceleration platform (MAP) for, catalyst discovery and system optimization. Toward this end, we present the automated GDE (AutoGDE) testing system. Given a catalyst-coated GDE, AutoGDE automates the insertion of the GDE into an electrochemical cell, the liquid and gas handling, the quantification of gaseous reaction products via online mass spectroscopy, and the archiving of the liquid electrolyte for subsequent analysis.
Activation of Primary C-H Bonds in Oxidative Cyclizations of Tambjamines Catalyzed by Rieske Oxygenases TamC and PtTamC
Authors: Ramachandra Manasa , Yu Jian , Howe Graeme , Sauriol Francoise , Oleschuk Richard , Ross Avena
Published: March 2024

Tambjamines are complex bipyrrole-containing natural prod-ucts that possess promising bioactive properties. Although Pseudoalteromonas citrea is known to produce both cyclic tambjamine MYP1 and the linear precursor (YP1), the biosynthetic machinery used to catalyze the site-selective oxidative carbocyclization at the unactivated 1° carbon of YP1 has re-mained unclear. Here, we demonstrate that a three-component Rieske system consisting of an oxygenase (TamC) and two redox partner proteins is responsible for this unprecedented activity on YP1 and a non-native substrate (BE-18591). We also show that a homologous oxidase from Pseudoalteromonas tunicata (PtTamC) can function together with the partner proteins from P. citrea to process both YP1 and BE-18591. These reactions represent the first Rieske oxygenase-catalyzed activations of C-H bonds at 1° carbons. The use of TamC and PtTamC to generate the new-to-Nature cyclic analogue of BE-18591 illustrates the enormous biocatalytic potential of these Rieske systems to facilitate late-stage oxidative cyclizations at terminal C(sp3)-H bonds.
Oxygen-assisted supercapacitive swing adsorption of carbon dioxide
Authors: Bilal Muhammad , Li Jiajie , Kumar Neelesh , Mosevitzky Bar , Wachs Israel , Landskron Kai
Published: March 2024

We report enhanced supercapacitive swing adsorption (SSA) of carbon dioxide in the presence of oxygen using activated carbon electrodes, and deliquescent, aqueous electrolytes. The presence of O2 in the gas mixture results in up to 11 times increased CO2 adsorption capacity with 3M MgBr2 and up to 4-5 times increased adsorption capacity with 3M MgCl2. Varying the oxygen concentration (5-20% O2) does not affect the energetics and adsorptive performance. Cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) of the electrodes demonstrate that the specific capacitance increases while the diffusion resistance decreases in the presence of oxygen, indicating enhanced pore wettability, and the reversible formation of oxygen functionalities on the pore surfaces, which enhance the adsorption. The electrodes show good performance for more than 100 hours of operation.
Turistik Bir Ürün Olarak Çiçekdağı (Çiçekdağı as a Touristic Product)
Authors: Çetinkaya Filiz Özlem
Published: March 2024

Turistlerin ziyaretlerine açılan destinasyonlarda, destinasyonun sahip olduğu turizm ürünleri birbiri ile bütün halde ve uyumlu bir şekilde sunularak bir tatil deneyimi yaratılmaya çalışılmaktadır. Bir yerin turistik bir destinasyon olabilmesi için, kişilerde ziyaret etme güdüsü taşıyan çekicilikler; destinasyona ya da turizm işletmelerine ulaşılabilirlik; karnaval, festival, fuar, kongre, gibi etkinlikler; kişilerin turizm faaliyetlerini kolaylıkla gerçekleştirebilmeleri için ihtiyaç duyacakları konaklama işletmeleri, yiyecek-içecek işletmeleri, ulaştırma işletmeleri gibi turizm işletmeleri; destinasyonun ve turizm işletmelerinin kişilerin algılarında oluşturduğu ve kişilerin destinasyonu ziyaret etme niyetlerini büyük ölçüde etkileyen öğelerden biri olan imaja sahip olması gerekir. Bir destinasyonun turistik bir ürün olarak değerlendirilebilmesi için bu beş unsura sahip olması gerektiği göz önünde bulundurularak çalışmada Çiçekdağı destinasyonunun turizm ürününü oluşturan unsurlar açısından ele alınıp turis tik bir ürün olarak değerlendirilmesi amacıyla literatür taraması yapılmıştır. Çalışma sonunda Çiçekdağı’nın turistik ürün unsurlarını ne derecede taşıdığı ortaya konulmuş ve destinasyonun turistik ürün unsurlarını karşılama derecesine göre çeşitli önerilerde bulunulmuştur. Bu çalışma 24-26 Kasım 2022 tarihleri arasında Her Yönüyle Çiçekdağı Sempozyumu’nda tam metin bildiri olarak sunulmuştur.
Study on the Integration of Ideological and Political Education and Students’ Mental Health Education
Authors: Jiang Piaoyi
Published: March 2024

In the new era, the rapid advancement of Internet technology has promoted the development of social economy and education. Although the current education conditions and education system of colleges and universities have been significantly improved, the attention to students’ mental health education is low. Nowadays, there is various uneven and unhealthy information on the Internet, which will negatively impact the shaping of correct values in students, and play an essential role in improving students’ discrimination ability. Therefore, it is very important to realize the good integration between ideological and political education and students’ mental health education in college education, which can promote the all-round development of students. Based on this, this paper mainly focuses on the integration of ideological and political education and students’ mental health education, so as to provide theoretical reference for the smooth development of relevant research in the future.
Geogebra Software as A Guideline for Meaningful Learning of Mathematical Content for Ninth- Grade Students in Ecuador – A Secondary Publication
Authors: Chulde Oscar Marcelo Pantoja
Published: March 2024

The introduction of the GeoGebra software led to a considerable increase in the interactivity of the didactic sequence of learning mathematical contents, a scenario that highlighted the inclusion of the meaningful learning model as the basis of pedagogical proposals. In this sense, the objective of this article was to determine the relationship of the GeoGebra software in the learning of mathematics in ninth-grade students in the General Education (GE) of the Yaruquí Public Educational Unit. Relational research with a non-experimental and transversal design was carried out to measure the variables in 44 ninth-grade students through the collection of data using valid and reliable instruments. The results indicated that a large number of students deemed the interface and interactivity of the GeoGebra software as “appropriate” (> 60%) and showed high levels of information acquisition and incorporation of new knowledge (68.2%). The correlational analysis revealed positive directions and moderate levels between the dimensions of the two variables (0.430 < Rho < 0.515); overall, a direct and moderate correlation was observed between GeoGebra software and mathematical learning (Rho = 0.549, R2 = 0.301). Finally, it was concluded that higher scores in the dimensions of GeoGebra software would manifest in high scores for meaningful learning of mathematical content.
The 6th Victor de Mello Goa Lecture: Development of large direct shear facility for geotechnical characterization and stability assessment of opencast mines dumps
Authors: Gara Sravan , Rao K.
Published: March 2024

As opencast coal production increases, a crucial challenge is safeguarding the stability and management of overburden dumps while prioritizing both safety and cost-efficiency. Determining the optimal stable dump slope dimensions during and after mining remains a key challenge for mining operations worldwide. Assessing the stability of overburden (OB) dumps is necessary to maintain them at the steepest possible angle without compromising stability. Understanding the shear strength, including cohesion and angle of internal friction, of the heterogeneous dump mass is crucial for this assessment. To evaluate the shear strength behaviour of OB materials, a large direct shear machine (LDSM) was designed and developed at Central Mine Planning and Design Institute, Ranchi. The LDSM features a shear box with dimensions of 1000 mm × 1000 mm × 1000 mm to facilitate testing materials with larger particle sizes. It can test large specimens with a thickness up to 500 mm and a maximum particle size (Dmax) of 80mm in accordance with ASTM D3080-98. Seven different OB materials from Magadh Coalfields, India were collected and tested for their shear strength. Using the obtained shear strength parameters, various slope profiles are assessed for stability using 2D limit equilibrium software such as Slide2 and GALENA. Probabilistic modelling is employed to generate a statistically distributed factor of safety (FoS) instead of a deterministic value, accounting for uncertainties related to input parameters. This paper aims to forecast the maximum safe height for OB dumps based on the determined shear strength parameters.
Impacto do Zika vírus na saúde materno-infantil no nordeste brasileiro: um estudo descritivo e retrospectivo
Authors: França Bruna Stefany Rebouças , Fernandes Gustavo Peixoto de Oliveira , Almeida João Paulo Oliveira de , Costa Mariana Ivo , Rocha Sophya Bezerra Silva , Machado Michael Ferreira
Published: March 2024

Objetivo: Analisar o perfil epidemiológico, associando os números de casos confirmados de Zika vírus nas regiões brasileiras com a incidência de síndrome congênita do Zika vírus, com ênfase no Nordeste. Método: É um estudo descritivo retrospectivo, feito com dados secundários disponibilizados pelo Ministério da Saúde. Resultados: Após análise dos dados, evidencia-se que o Nordeste é a região brasileira que mais sofreu com os efeitos neuropatogênicos do vírus devido a uma série de fatores sanitários e socioeconômicos. Conclusão: Não obstante a finalização do estado de emergência sanitária, o Nordeste ainda concentra o maior número de casos, o que sinaliza a necessidade de serem feitos esforços político-sanitários a fim de diminuir ao máximo os danos desse vírus às famílias nordestinas.
Telecuidado na Pandemia de Coronavírus: Promovendo a Alfabetização em Saúde de Idosos
Authors: Silva Beatriz Lúcio Miranda da , Silva Magda Vitória Nunes da , Nunes Erika Maria Barbosa , Marcolino Aylla Rafaella Quintela , Lopes Thayná Brenna de Lima , Serbim Andreivna Kharenine
Published: March 2024

RESUMOObjetivo: descrever a experiência de estudantes e docente do Curso de Enfermagem na condução da ação de extensão Telecuidado, realizada com idosos usuários de uma unidade básica de saúde durante a pandemia de coronavírus. Método: trata-se de um relato de experiência das estudantes e docente sobre a experiência de realizar ligações telefônicas e produção de material educativo para idosos de uma unidade básica de saúde no período de 16 semanas, mediante um roteiro estruturado que visava o desenvolvimento das habilidades de alfabetização em saúde dos idosos. Resultados: as ações do Telecuidado estimularam as estudantes a atuar com ênfase no âmbito social, cultural e científico, utilizando tecnologias leves para promoção da saúde e do desenvolvimento de habilidades dos idosos, a fim de que os mesmos se tornassem multiplicadores de informações e transformadores da realidade social. Os 36 idosos atendidos obtiveram uma rede de apoio e compartilhamento de informações em saúde, além das ligações contribuírem para redução da circulação dos idosos na unidade de saúde, evitando aglomerações e minimizando o risco de exposição à doença. Conclusão: a experiência proporcionou o desenvolvimento de habilidades de alfabetização em saúde dos idosos e aprimorou a assistência de saúde.