bluuebunny/crossref_metadata_2025 huggingface dataset:
REED PHYTOCENOSIS OF THE SOUTHERN PRIARALIE AND ITS CURRENT STATE
Authors: Косназаров К.А. , Мелдебекова С.У. , Абдуллаева Ж.К. , Аташов А.Ш. , Сабурова Ш.Б. , Косназаров К.К.
Published: February 2022

Увеличение объема площади тростниковых зарослей и их фитоценозов в Каракалпакстане создает возможности для удовлетворения потребностей в сырье для (изготовления) производства бумаги, целлюлозы, лекарств, строительных материалов и других продуктов сельского хозяйства и оказывает огромную помощь нашему народу в обеспечении необходимыми рабочими местами.

The increase in the area of ​​reed thickets and their phytocenoses in Karakalpakstan creates opportunities to meet the needs for raw materials for (manufacturing) the production of paper, cellulose, medicines, building materials and other agricultural products and provides a huge help to our people in providing the necessary jobs.
SPATIAL DISTRIBUTION OF PHYTOCOENOSES IN A NEAR-TERRACE PART OF OB RIVER FLOODPLAIN BY TUNDRINSKIY KEDROVYY BOR (KHANTY-MANSI AUTONOMOUS OKRUG)
Authors: Тюрин В.Н. , Богданова Д.В.
Published: February 2022

Представлены сведения о распределении растительных сообществ на профиле, пересекающем западную часть Тундринского кедрового бора. Обследованный участок протяженностью 1,2 км к югу от кедрового массива охватывает притеррасную пойму Оби. Рассмотрен вопрос о связи фитоценозов с рельефом, половодьем, торфонакоплением.

The data on distribution of plant communities on a profile crossing the western part of the Tundrinskiy Kedrovyy Bor are presented. The surveyed section extends 1.2 km south from the siberian pine massif and covers a near-terrace floodplain of the Ob River. A question of connecting the phytocoenoses with relief, flooding and peat accumulation is considered.
ON THE POSSIBILITIES OF IN VITRO POLLINATION OF NICOTIANA TABACUM LIN. WITH POLLEN OF AUSTRALIAN WILD SPECIES OF THE GENUS NICOTIANA
Authors: Ларькина Н.И.
Published: February 2022

Виды рода Nicotiana являются идеальным модельным объектом для проведения исследований в разных биологических направлениях. Это позволяет изучать разнообразные признаки растений, разрабатывать методы и приемы, изыскивающие возможности преодоления генетических несовместимостей, получать новые генотипы и определять закономерности биологии их развития. Для создания новых генотипов применим метод опыления in vitro вида N. tabacum Lin, взятого материнской формой; пыльцой австралийских диких видов рода Nicotiana, что позволило получить гибридные семена новых генотипов при участии N. rosulata, N. amplexicaulis, N. debneyi и преодолеть генетическую несовместимость, возникающую между видами при получении семян.

Species of the genus Nicotiana are an ideal model object for research in various biological directions. This allows us to study a variety of plant traits, develop methods and techniques that seek ways to overcome genetic incompatibilities, obtain new genotypes and determine the patterns of the biology of their development. To create new genotypes, the method of in vitro pollination of the species N. tabacum Lin, taken from the maternal form; pollen of Australian wild species of the genus Nicotiana, was used, which allowed us to obtain hybrid seeds of new genotypes with the participation of N. tabacum Lin. rosulata, N. amplexicaulis, N. debneyi and overcome the genetic incompatibility that occurs between species when obtaining seeds.Keywords: Genotype, non-crossability, genus, species, method, pollination, in vitro, maternal form, pollinator,
ПОДГОТОВКА БУДУЩЕГО УЧИТЕЛЯ К ИННОВАЦИОННОЙ ПЕДАГОГИЧЕСКОЙ ДЕЯТЕЛЬНОСТИ
Authors: Искендерова Н.К. , Карабалаева Г.Т.
Published: February 2022

В статье анализируется дефиниции «инновация», «инновационная деятельность», которая представлена разными источниками. Инновационная деятельность и ее процесс во многом зависят от инновационного потенциала педагога. Рассматриваются возможности психолого-педагогических дисциплин, в процессе преподавания которого использовались различного рода инновации в образовательном процессе профессионального колледжа.
ИССЛЕДОВАНИЕ РУССКИХ СВАДЕБНЫХ ОБРЯДОВ
Authors: Хань Ц. , Чжао С.
Published: February 2022

Статья посвящена исследованию свадебного обряда как социальной и культурной практики общества. Традиционная свадьба рассматривается как ресурс современной свадебной церемонии. Свадьба анализируется с точки зрения носителей духовных ценностей и смыслов. Автор обращает внимание на такие ключевые понятия, как свадебные обряды, традиции, потребности людей.
Photoswitching neutral homoaromatic hydrocarbons
Authors: Tran Ngoc Trung , Grabicki Niklas , Irran Elisabeth , Dumele Oliver , Johannes Teichert
Published: February 2022

The identification and characterization of homoaromatic compounds bearing an interrupted -system are fundamental challenges for the understanding of electronic interactions in organic molecules. This is further hampered by the fact that no stable neutral homoaromatic hydrocarbon is known. We present the preparation of a new class of neutral homoaromatic compounds, which are supported by experimental evidence (ring current observed by NMR spectroscopy, equalization of bond lengths through X-ray structure analysis) as well as computational analysis (NICS and ACID). Furthermore, we show that one homoaromatic hydrocarbon is a photoswitch through a reversible photochemical [1,11] sigmatropic rearrangement. We provide evidence that the local 6 homoaromatic state vanishes upon photoswitching to produce a purely global 10 homoaromatic state. These results of stable and accessible homoaromatic neutral hydrocarbons and their photoswitching behaviour provide new insights for the understanding and study of homoconjugative interactions in organic molecules, and for the design of new responsive molecular materials.
Profiling Sulfur(VI) Fluorides as Reactive Functionalities for Chemical Biology Tools and Expansion of the Ligandable Proteome
Authors: Gilbert Katharine , Vuorinen Aini , Aatkar Arron , Pogany Peter , Pettinger Jonathan , Grant Emma , Kirkpatrick Joanna , Rittinger Katrin , House David , Burley Glenn , Bush Jacob
Published: February 2022

Chemical probes are valuable tools to explore the function of proteins. Incorporation of electrophiles into small molecules enables covalent capture of protein interactions and provides access to powerful technologies including chemoproteomic profiling and reactive fragment screening. Current approaches have been largely limited to protein pockets containing cysteine, so establishing strategies to target other amino acid residues is essential to expanding the applicability across the proteome. Here, we profiled sulfur(VI) fluorides (SVI-F) as reactive functionalities that can modify multiple residues including Lys, Tyr, His and Ser, thus offering utility for targeting almost any protein. These studies provided an in-depth understanding of SVI-F functionalities, including hydrolytic stability, protein reactivity and utility in chemoproteomics. Such insights offer a valuable guide for the prospective design of SVI-F-containing ligands for various chemical biology workflows and illustrate the wide range of proteins that SVI-Fs can capture, thus highlighting the opportunity for SVI-Fs to expand the liganded proteome.
Zwitterionic Osmolytes Employ Dual Mechanisms for Resurrection of Surface Charge under Salt-stress
Authors: Sarkar Susmita , Guha Anku , Narayanan T. N. , Mondal Jagannath
Published: February 2022

Salt imbalance in cells is a major detrimental abiotic stress which causes ionic toxicity and disrupts important cellular functions. To counter this saline stress, cell often produces low molecular weight cosolutes, known as osmolytes, which have the ability to resuscitate homeostasis. Here we combine atomistic computer simulation, contact angle measurements and Raman spectroscopic analysis to identify the mechanistic role of multiple osmolytes (glycine, TMAO and betaine) in modulating the electrostatic interaction under salt stress, a slowly emerging aspect of osmoprotection. By utilising a pair of negatively charged silica surfaces in a ternary mixture of osmolyte and KCl solution as a proxy of charged surface of biomacromolecule, our investigation reveals that all three osmolytes are able to resurrect the electrostatic interaction between the two surfaces, which had been otherwise charge-screened by excess salt. The joint venture of experiment and simulation discover dual and mutually exclusive mechanisms of recovering charge interaction by zwitter-ionic osmolytes. However, the relative ability and the underlying mechanism of revival of electrostatic interactions are found to be strongly dependent of chemical nature of osmolyte. Specifically, glycine was found to competitively desorb the salt-ions from the surface via its direct interaction with the surface. On the other hand, TMAO and betaine counter-act salt stress by retaining adsorbed cations but partially neutralising their charge-density via ion-mediated interaction. We believe that the access to dual and mutually alternative modes of osmolytic actions, as elucidated here, would provide the cell the required adaptability in combating salt-stress.
Visible Light Promoted Stereoselective C(sp3)-H Glycosylation for the Synthesis of C-Glycoamino Acids and C-Glycopeptides
Authors: Qi Rupeng , Wang Chao , Ma Zijian , Wang Hongying , Chen Qiao , Liu Liangyu , Pan Da , Ren Xiaoyu , Wang Rui , Xu Zhaoqing
Published: February 2022

Glycosylative modification of peptides could improve the pharmacological properties of peptide drugs and deliver them efficiently to the target sites. Compared with O-/N-glycosides, C-glycosides exhibit more metabolic stability. We here disclose the first example of visible-light promoted and Cu-catalyzed stereoselective C-glycosylations. The mild reaction conditions are compatible with various carbohydrate substrates, including a series of mono monosaccharides and disaccharide, and is amenable to the synthesis of a wild variety of C-glycoamino acids and C-glycopeptidomimetics with good yields and excellent stereoselectivities. The dual-functional photocatalyst formed in situ via coordination of glycine derivatives and chiral phosphine Cu complex could not only catalyze the photoredox process but also control the stereoselectivity of glycosylation reaction.
FORMATION OF A STRATA OF INNOVATORS IN THE SOCIAL STRUCTURE OF RUSSIAN SOCIETY IN THE CONTEXT OF DIGITALIZATION. THE ROLE OF THE STATE
Authors:   Russian State University for the Humanities, Illarionova Elina O.
Published: February 2022

The article considers the specifics in the formation of the innovators strata for the social structure of Russian society in the context of the ongoing digitalization process. It pays special attention to the role of the state in the process, and analyzes main forms of the state support for the innovative development in the Russian Federation. It also shows the interrelation of the concepts of “knowledge economy”, “digital economy” and digitalization and highlights and studies the main directions of digitalization in the innovative sector of the economy as well as the advantages of digitalization of the first and second order. Particular attention is paid to the analysis in the development of the innovative potential of human capital in Russia. The basic factors hindering innovative development are derived. The processes of social dynamics in Russian society in the field of creating an innovative and digital environment are investigated. The author proves an urgency of the development and implementation for the system of public-private partnership in the field of high technologies. A brief analysis of regulatory documents in the field of digitalization and innovative development is presented.
MEDIA ACTIVITY OF NEW POLITICAL PARTIES ON THE EVE OF ELECTIONS TO THE STATE DUMA OF THE VIII CONVOCATION. SOCIOLOGICAL ANALYSIS
Authors:   Russian State University for the Humanities, Velikaya Nataliya M. ,   Institute of Socio-Political Research of the Federal Center of Theoretical and Applied Sociology of the Russian Academy of Sciences,, Malinin Aleksei Yu. ,   Institute of Socio-Political Research of the Federal Center of Theoretical and Applied Sociology of the Russian Academy of Sciences
Published: February 2022

In September 2021 elections of deputies of the State Duma of the Federal Assembly of the Russian Federation will be held, where a number of new political parties take part, as well as parties that, due to a certain rebranding, can be designated as “renewed”. From the beginning of 2020, those parties began to engage in their promotion within the framework of the election campaign in various regional legislative bodies of state power. Due to the fact that almost all the new party projects under study had previously got seats in a number of legislative assemblies, they could be elected to the State Duma without collecting signatures. Considering that less than a month is left until the single election day, the authors decided to analyze the activities of those parties in terms of promotion in traditional and online media in order to assess the overall level of activity in the election campaign and trace its connection with the prospects for new political parties to enter the Russian Parliament. The authors also classify the parties under study by their type of organization, ideological orientation and determine the intermediate results of their activities within the framework of the election campaign.
Towards an understanding of post-translation studies: A comparative analysis of cultural transfer in the rewritings of popular literature
Authors: ÖZBEK Dudu , SÖYLEMEZ Ayşe Selmin
Published: February 2022

With the technological developments and the globalization process especially after the 1980s, translations have gained new functions as ‘cultural products’ that are consumed by the people in various parts of the world. Today, works of popular literature can reach people from diverse cultures in a very short time through translation. These new conditions require the evaluation of the socio-cultural functions of these translations with a new perspective in the field of translation studies. In order to analyze these functions of the translated texts, Edwin Gentzler (2017) proposes a framework with the name ‘post-translation studies’. Within this framework, Gentzler (2017) draws attention to focus on translation as a form of rewriting and to investigate pre-translation and post-translation conditions in the receiving societies. Gentzler’s (2017) approach emphasizes to analyze the translations in their social contexts and to trace the socio-cultural changes that take place in these societies after the translations are put into circulation. As part of ‘post-translation studies’, this article aims to investigate how Turkish translations of a representative of American popular literature presented American cultural elements in the 1980s and in the 2010s as forms of different rewritings. To this end, Turkish translation of Stephen King’s IT in 1987 and its retranslation by the same publisher in 2015 were compared in terms of the representation of the culture specific items. The analyses were based on Pavlovic and Poslek’s (1998) categorization of the culture specific items and Aixela’s (1996) categories of the translation strategies, which were grouped as being source-oriented and target-oriented on the macro level. Evaluating the results in relation to the socio-cultural context of the receiving society in the 1980s and the cultural changes that have occurred until the retranslation was published, it was found out that American cultural items in the source text were predominantly translated with target-oriented strategies in the initial translation in 1987 and they were mostly translated with source-oriented strategies in the retranslation in 2015. It was also observed that the familiarity of the items belonging to American culture highly increased for the Turkish readers in the 28-year period as a result of the influence of the source culture.
Управление коммуникациями
Authors:   Федеральный научно-исследовательский социологический центр РАН, Чумиков Александр Николаевич , Бочаров Михаил Петрович ,   Российский научно-исследовательский институт региональных проблем
Published: February 2022

В учебнике представлен универсальный блок профессиональных компетенций специалиста по коммуникациям (рекламе и связям с общественностью, журналистике и медиакоммуникациям), а также раскрыты особенности коммуникаций в различных стратегических моделях взаимоотношений важнейших субъектов социальной жизни: государственных (G), коммерческих (B), неправительственных организаций; отдельных граждан (C). Содержатся многочисленные коммуникационные кейсы, сформулированы контрольные вопросы и задания для проверки усвоения теоретического материала. Для студентов бакалавриата и магистратуры, обучающихся по направлениям подготовки «Реклама и связи с общественностью »,«Журналистика и медиакоммуникации », а также преподавателей и практических специалистов по коммуникациям.
Духовная экономика и совместимость: теория совместимости
Authors:   Московский государственный университет им. М.В. Ломоносова, Морозов Владимир Александрович
Published: February 2022

Работа посвящена исследованию структуры общества и взаимоотношений его подсистем в окружающей среде. Целью исследования является формирование совместимой модели общества и методов взаимодействия его подсистем в окружающей среде. В книге раскрывается теоретико-методологическое содержание взглядов на развитие общества и подсистем его жизнедеятельности. Проведен анализ противоречий подсистем общества и доминирования направлений в их развитии. Определены общие предпосылки совместимости научных школ в экономике и управлении, с выявлением сходств и различий в подходах изучения проблем. Разработана спирально-цикличная структурная модель общества и раскрыто её теоретическое содержание. Сформированы методы решения задач совместимого развития подсистем общества с окружающей средой. Существенное место в книге отведено раскрытию эволюции перехода от моральной экономики к нравственной и духовной экономике. Обоснованы: содержание духовной экономики как основного фактора совместимости человеческих потребностей и общественных ценностей; ориентация мирового хозяйства на критерии функционирования духовной экономики (духовно-синергетический подход); метод измерения состояния и динамики духовной экономики на базе сформированных групп показателей. Рекомендуется широкому кругу экономистов, социологов, политологов, управленцев, представителей культур, маркетологов, а также магистрам, аспирантам и научным работникам.
Carbonización hidrotermal del nejayote de maíz
Authors: Loredo Cancino Margarita , Arriola Gil Yair Yosías , Soto Regalado Eduardo , Dávila Guzmán Nancy Elizabeth
Published: February 2022

Los residuos líquidos del proceso de nixtamalización (nejayote) representan un problema ambiental debido a sus característicasfisicoquímicas y la disposición inadecuada de estos residuos por parte de algunos molinos. En esta investigación se propone el método de carbonización hidrotermal para el aprovechamiento del nejayote, ya que este método permite trabajar con biomasas que presenten un gran contenido de humedad. El nejayote fue obtenido en condiciones de laboratorio y se introdujo en un reactor hidrotermal con capacidad de 100 mL bajo las condiciones establecidas por un diseño de experimentos central compuesto. Una vez separados los productos resultantes (líquido y sólido), se secó la muestra sólida y se calcularon rendimientos. Posteriormente se buscaron las condiciones experimentales que maximizaran el rendimiento, encontrando el punto óptimo a una temperatura de carbonización de 200 Celsius, pH de 3.3 y un tiempo en el rango de 12 a 24 horas; a estas condiciones se predice un rendimiento de 30 % con una deseabilidad de 0.919.
Producción sustentable de biodiesel empleando grasas residuales de la industria láctea
Authors: Medellín Castillo Nahum Andrés , Rangel Nava Bladir Salomón , Rocha Uribe Alejandro , Aguilera Flores Miguel Mauricio , Ávila Vázquez Verónica
Published: February 2022

En este trabajo se evaluó la recuperación de grasas de una empresa pasteurizadora de leche para su uso en la producción de biodiesel con la finalidad de aprovechar los residuos lácteos y reducir los problemas relacionados con la generación de biosólidos en la planta de tratamiento de aguas residuales (PTAR) de dicha empresa. La producción de biodiesel se realizó por transesterificación en fase homogénea y heterogénea utilizando como materia prima los residuos grasos. Para los dos procesos, se evaluó el rendimiento de producción de biodiesel y la calidad del biodiesel de acuerdo a la norma europea EN 14214. La reacción en fase homogénea se realizó empleando metanol y grasa residual en una proporción molar de 6:1 (metanol:grasa), NaOH como catalizador al 0.8 % p/p con respecto a la masa de la grasa, temperatura de 60 °C y un tiempo de reacción de 60 minutos. Para la reacción en fase heterogénea, se utilizó un hidróxido doble laminar (HDL) como catalizador heterogéneo al 3.5 %p/p, una relación metanol-grasa de 21:1, temperatura de 60 °C y tiempo de 60 min. Los rendimientos de la reacción fueron del 97.5 y 98.5 % p/p, con base en el peso de la grasa empleada, para la reacción homogénea y heterogénea, respectivamente. Además, se encontró que el biodiesel sintetizado en las dos reacciones cumple con los parámetros de calidad de la norma EN14214. Finalmente, la tecnología desarrollada en este estudio constituye una alternativa de producción de una fuente de energía con beneficios sustentables.
Investigation of The Effects of Processing Parameters on Measuring Accuracy in Electro Erosion Machining of Ti-6Al-4V Alloy
Authors: CAKIROGLU Ramazan
Published: February 2022

Titanium alloys are one of the materials that are difficult to process due to their high strength, high hardness and low thermal conductivity, wherefore low tool life and surface quality and high energy consumption are involved in shaping them with traditional manufacturing methods. In particular, special tool geometries are required for the machining of complex geometry parts including helical groove, keyseat, micro-holes, etc. with traditional manufacturing methods, which leads to increases in machining costs. In such cases, non-traditional alternative processing methods are preferred. In this study, keyseat shaping procedures were performed according to DIN 6885 standard in the electro (die-sinking) erosion machine for Ti-4Al-6V alloy. As a result of experiments conducted in copper electrode and Belone EDM F dielectric fluid environment, the effects of different processing parameters (discharge current, pulse on time and pulse off time) on measuring accuracy were investigated. In addition, the effects of 3D surface and SEM images and processing parameters on the accuracy of the coordinate measurement were evaluated. With the low discharge current, less thermal energy is transferred to the workpiece and smaller particles are removed from the workpiece, obtained in closer results to the targeted values. The biggest difference between the targeted keyseat depth, width and length and the measured value was 18.13%, 4.24% and 0.625%, respectively. The results closest to the specified standard keyseat dimensions were obtained in Ip=9A, Ton=150μs, Toff=120μs processing parameters.
Sosialisasi dan Pendampingan Pengembangan Bahan Ajar IPA Berbasis Multi Level Representasi Pada Alumni Pendidikan Kimia Universitas Mataram
Authors: Wildan Wildan , Laksmiwati Dwi , Siahaan Jeckson , Telly Savalas Lalu Rudyat , Supriadi
Published: February 2022

Pembelajaran kimia yang lengkap adalah pembelajaran yang menghubungkan tiga level representasi kimia, yaitu level makroskopik, simbolik, dan submikroskopik. Dengan pembelajaran berbasis multi level representasi, mahasiswa dapat menjelaskan konsep kimia secara ilmiah tanpa ada miskonsepsi. Program ini bertujuan untuk mensosialisasikan dan mendampingi alumni pendidikan kimia yang sudah menjadi guru dalam mengembangan pembelajaran kimia berbasis multilevel representasi sebagai upaya untuk meningkatkan kemampuan siswa dalam menghubungkan tiga level representasi. Ada beberapa tahapan yang dilakukan selama pengabdian, yaitu persiapan, sosialisasi, pendampingan, Workshop hasil kerja peserta, dan monitoring, evaluasi serta pelaporan. semua tahapan dilaksanakan secara daring. Kegiatan ini berjalan dengan lancar sesuai perencanaan dan memberikan hasil positif bagi peserta. Peserta kegiatan sangat antusias mengikuti kegiatan yang dilaksanakan. Materi pengabdian diakui sangat berguna bagi para guru terutama dalam pengembangan dan penggunaan bahan ajar berbasis multi level representasi yang diharapkan dapat membuat siswa memahami kimia melalui tiga level representasi.
Workshop Penyusunan Karya Tulis Ilmiah (KTI) Bagi Widyaiswara BPSDM Propinsi NTB
Authors: Rahmawati Rahmawati , Muti'ah Muti'ah , Al-Idrus Syarifa Wahidah
Published: February 2022

Widyaiswara pada kantor BPSDM NTB mempunyai tugas pokok mempublikasikan karya tulis ilmiah sebagai salah satu syarat mendapatkan angka kredit untuk kenaikan pangkat fungsional. Keterbatasan kemampuan menulis KTI menyebabkan widyaiswara kesulitan untuk melakukan publikasi. Workshop ini diselenggarakan untuk melatih widyaiswara menyusun karya tulis ilmiah untuk dipublikasikan pada seminar atau jurnal yang sesuai. Hasil workshop menunjukkan antusias para widyaiswara mengikuti kegiatan dan bersemangat melakukan penulisan. Tulisan yang telah atau masih dalam bentuk draft didampingi penulisannya sampai menjadi tulisan yang layak dan siap submit. Tindak lanjut dari kegiatan workshop ini adalah pendampingan penulisan yang menghasilkan: satu tulisan siap submit pada jurnal JSEH milik LPPM Unram, 1 jurnal lainnya telah submit pada jurnal Bestari milik BPSDM NTB, 1 draft tulisan yang disajikan pada seminar penjenjangan intern BPSDM, dan 1 tulisan telah diseminarkan pada Semnas Saintek LPPM Nopember 2020.
Assessing Different Media Composition on Germination, Growth and Yield of Transplanted Sesame (Sesamum indicum L.)
Authors:   Department of Agronomy, Agricultural College and Research Institute, Madurai - 625 104, M Aasif , V K Paulpandi ,   Department of Agronomy, Agricultural College and Research Institute, Madurai - 625 104, R Durai Singh ,   Department of Agronomy, Agricultural College and Research Institute, Madurai - 625 104, P Saravanapandian ,   2Department of Soils and Environment, Agricultural College and Research Institute, Madurai - 625 104, T Sivakumar ,   Department of Seed Science and Technology, Agricultural College and Research Institute, Madurai - 625 104
Published: February 2022

Sesamum, a traditional oilseed crop, is susceptible to poor plant establishment due to various biotic and abiotic factors for which transplanting is a suitable option. Still, suitable media for promoting the growth and establishment of sesame seedlings have not yet been exploited. Therefore, a preliminary field experiment was conducted in 2019 at Agricultural College and Research Institute, Tamil Nadu Agricultural University, Madurai, India, to study the effect of various media compositions on the performance of transplanted sesame. Media compositions such as red earth, FYM, vermicompost and composted coir pith were used. The experiment was laid out in randomized block design with four replications. Results revealed that higher seed germination percentage ( 88), establishment percentage (94), vigor index (1674), seedling height (15 cm), capsules plant-1(83), seeds capsule-1 (58), and seed yield ( 839 kg ha-1) were recorded in media comprising red earth: sand: vermicompost: composted coir pith (2:1:1:1) followed by red earth: sand: vermicompost (2:1:1). Therefore, the media composition of red earth: sand: vermicompost: composted coir pith is highly suitable for promoting growth, seedling vigor, and yield enhancement in transplanted sesame.
Safety evaluation of hydroethanolic fruit extracts of Duranta erecta Linn
Authors: Shadrack Donkor  , Christopher Larbie  , Gustav Komlaga  , Benjamin Obukowho Emikpe
Published: February 2022

Background: Duranta erecta is used in traditional medicine for the treatment of myriad of diseases in most developing countries. The potential safety concerns associated with the administration of hydroethanolic fruit extracts of the plants were investigated in rats. Materials and Methods: Extracts were screened for their possible antioxidant activities by the DPPH scavenging activity. Bioactive compounds present in methanolic extracts of ripe and unripe fruits of D. erecta were identified using Gas chromatography–mass spectrometry (GC–MS). Male and female rats were grouped taking their body weights into consideration to achieve approximately equal conditions among the groups. A freshly prepared solution of DRR or DRU extract was administered orally at 100, 250 and 500 mg/kg b.wt. to different groups while normal group received distilled water daily for 28 days. Toxicity assessment was done using relative organ weight, haematological, and biochemical parameters and histological assessment. Results: The administration of extracts resulted in overall body weight increase, significant change in relative organ weight of the liver, changes in haematological index such as platelet and biochemical parameters namely ALT, AST, ALP, TBil, DBil, IBil, creatinine and urea of the tested group relative to the normal. Histological observations showed normal hepatocytes. Conclusion: The findings suggest that hydroethanolic Duranta erecta fruit extracts is safe but its prolonged use may have some level of adverse effect on the liver.
PENGARUH UKURAN PERUSAHAAN, AUDIT TENURE, KUALITAS AUDIT, DAN AUDIT REPORT LAG TERHADAP OPINI AUDIT GOING CONCERN
Authors: Haalisa Shulasi Nur , Inayati Nur Isna
Published: February 2022

This study aims to analyze the effect of company size, audit tenure, audit quality and audit reportlag on going concern audit opinion. This research is a quantitative research. The data source usedis secondary data in the form of the company's annual financial statements. In this study, goingconcern and audit quality are calculated using a dummy. The population used in this study ismining companies listed on the Indonesia Stock Exchange from 2015 to 2019. Sampling wascarried out by purposive sampling technique method and obtained 29 as 145 observed data. Theresults of this study show that company size, and audit tenure have no effect on going concernaudit opinion. While audit report lag and audit quality heve efeect on going concern opinion
PENGARUH RASIO KEUANGAN TERHADAP KINERJA KEUANGAN PADA KOPERASI PRIMKOPAL LANAL TEGAL
Authors: Kinasih Damar , Kamaluddin Nurhadi
Published: February 2022

Penelitian ini bertujuan untuk mengetahui pengaruh dari rasio likuiditas menggunakan current ratio, rasio solvabilitas menggunakan total debt to total asset, rasio rentabilitas menggunakan return on asset (ROA) secara parsial maupun simultan terhadap kinerja keuangan Koperasi Primkopal Lanal Tegal menggunakan sisa hasil usaha (SHU). Penelitian ini merupakan penelitian kuantitatif dengan menggunakan data sekunder berupa analisis rasio laporan keuangan bulanan pada Koperasi Primkopal Lanal Tegal dari tahun 2017 hingga tahun 2020.Penelitian ini menggunakan analisis regresi linier berganda untuk melihat pengaruh variabel independen yaitu Rasio Likuiditas (X1), Rasio Solvabilitas (X2) dan Rasio Rentabilitas (X3) terhadap Kinerja Keuangan yaitu menggunakan Sisa Hasil Usaha (Y). Hasil dari penelitian ini yaitu rasio likuiditas berpengaruh terhadap kinerja keuangan menggunakan Sisa Hasil Usaha, rasio solvabilitas  berpengaruh negatif terhadap kinerja keuangan menggunakan Sisa Hasil Usaha, dan rasio rentabilitas berpengaruh positif terhadap kinerja keuangan menggunakan Sisa Hasil Usaha. Hasil dari rasio likuiditas, rasio solvabilitas, dan rasio rentabilitas secara simultan berpengaruh terhadap kinerja keuangan menggunakan Sisa Hasil Usaha dengan nilai koefisien determinasi sebesar 82,4%.
PROFESIONALISME APARATUR DESA DALAM MENYELENGGARAKAN PELAYANAN PUBLIK PEMERINTAHAN DESA (STUDI KASUS DI KANTOR DESA JATINOM KABUPATEN BLITAR)
Authors: Sabrina Jihan , Umiyati Sri , Raharja Wildan Taufik
Published: February 2022

Jatinom Village Apparatus organizes the public services in Blitar Regency. This study aims to analyze the professionalism of village officials in the Jatinom village office in Blitar. The research uses qualitative method with a case study approach. Data collection uses observation, interview, documentation with data collection techniques, presentation, condensation, and conclusions. There are four indicators to measure the professionalism of the village apparatus, namely 1) Competence 2) Effectiveness 3) Efficiency 4) Responsible. With six sub indicators, namely Skills, Knowledge, Quantity, Quality, and Time. The results showed that the Professionalism of the Village Apparatus in Organizing Public Services in Jatinom Village Office. There were two professional sub-indicators, namely skills and knowledge. Village officials have good public speaking. However, there are four sub-indicators, namely quantity, quality, time, and responsibility, such as the staffs do not have a set of target time, have different work experiences that affect service quality, and do not obey the working hours.
Palabras tejidas: método y uso de un tesauro multilingüe de la seda
Authors: Alba Pagán Ester , Gaitán Salvatella Mar , León Muñoz Arabella
Published: February 2022

El patrimonio europeo de la seda es un patrimonio integral que abarca tanto bienes materiales (telares, tejidos, hilos, etc.) como un importante patrimonio inmaterial lingüístico. Su importancia como patrimonio es indudable, pero aunque la seda ha tejido Europa y se sigue utilizando en numerosos contextos, la tejeduría tradicional está en riesgo por la pérdida gradual de artesanos que salvaguarden el conocimiento ancestral. Además, la seda sigue siendo relevante para las personas que experimentan conexiones vivas, personales y sociales con este patrimonio, el cual está vinculado a tantas historias de vida y relatos colectivos que ha generado numerosos vocablos propios. El modo en se han catalogado los bienes asociados a la seda es muy heterogénea debido a la falta de normalización de los catálogos de los museos que los custodian. Es por ello que el vocabulario del patrimonio de la seda procede de múltiples fuentes que se han mezclado a través del tiempo y el espacio, dando como resultado que la interoperabilidad de estos datos sea extremadamente complicada. Para abordar estos retos, el proyecto SILKNOW asumió el reto de crear un tesauro multilingüe que es la base de otras herramientas del proyecto, normaliza el vocabulario del tejido sedero y rescata el patrimonio inmaterial asociado a este. Este artículo presenta los fundamentos de la realización de este tesauro y su relación con la salvaguarda del patrimonio material y sobre todo, inmaterial.
Potensi Krim Ekstrak Etanol Daun Stroberi (Fragaria x ananassa var Duchesne) sebagai Tabir Surya
Authors: Pambudi Petrick Gilang , Suhartinah Suhartinah , Ansory Hery Muhamad
Published: February 2022

Ekstrak daun stroberi dilaporkan memiliki aktivitas tabir surya yang baik. Formulasi sediaan yang baik menjadi hal yang diperlukan untuk tahapan berikutnya. Penelitian ini bertujuan untuk mengetahui mutu fisik dari sediaan krim dan menentukan  nilai SPF krim ekstrak etanol daun stroberi (Fragaria x ananassa var duchesne) sebagai tabir surya.

Metode ekstraksi yang digunakan adalah refluks dengan pelarut etanol 96%. Analisis kandungan ekstrak dilakukan dengan kromatografi  lapis tipis (KLT). Konsentrasi ekstrak yang digunakan untuk membuat krim tabir surya adalah 0,250% ; 0,500% dan 1,000%. Evaluasi yang dilakukan pada sediaan adalah uji mutu fisik, uji stabilitas sediaan dan aktivitas tabir surya baik in vivo dengan uji iritasi pada kulit manusia dan in vitro dengan spektrofotometri UV-Vis.

Hasil penelitian ekstrak etanol daun stroberi didapatkan rendemen sebanyak 20,5% dan uji KLT menunjukan bahwa ekstrak daun stroberi positif mengandung flavonoid dan tanin. Krim ekstrak etanol daun stroberi yang paling baik pada konsentrasi 1,000% dengan nilai SPF sebesar 52,90.
Pengaruh Edukasi Terhadap Pengetahuan Swamedikasi Batuk pada Anak di Kecamatan Wonosari Kabupaten Klaten Jawa Tengah
Authors: Hanifah Inaratul Rizkhy , Safitri Annisa Nur , Purwidyaningrum Ika
Published: February 2022

Pengobatan sendiri atau swamedikasi merupakan salah satu cara masyarakat untuk mengobati suatu gejala penyakit tanpa menggunakan resep dari dokter. Pengetahuan akan swamedikasi yang benar sangat diperlukan agar batuk dapat disembuhkan dengan tidak disertai efek lain yang merugikan penderita. Tujuan dari penelitian ini untuk mengetahui pengaruh edukasi melaui media online terhadap tingkat pengetahuan masyarakat tentang swamedikasi batuk pada anak di Kecamatan Wonosari, Kabupaten Klaten, Jawa Tengah pada tahun 2020.

Penelitian ini merupakan penelitian kuantitatif dengan metode penelitian Quasi Eksperimental dengan teknik Two Group Pre Test-Post Test Control Group Design. Populasi dalam penelitian ini adalah orang tua yang memiliki anak di Kecamatan Wonosari Kabupaten Klaten. Sampel dalam penelitian ini berjumlah 268 orang. Alat pengambilan data menggunakan kuesioner yang telah di uji validitas dan reliabilitasnya.

Hasil penelitian menunjukan bahwa tingkat pengetahuan masyarakat padasaat dilakukan pre-test tergolong baik (41,04%), cukup (54,48%), kurang (4,48%), tidak baik (0%). Pemberian edukasi mampu meningkatkan pengetahuan responden ditunjukan dengan hasil pengetahuan post-test tergolong baik (89,55%), cukup (10,45%), tidak baik (0%), kurang (0%). Analisis uji Wilcoxon didapatkan nilai p 0,000 000 < nilai α 0,05 yang dapat diartikan bahwa pemberian edukasi melalui media online mempengaruhi pengetahuan masyarakat mengenai swamedikasi batuk pada anak.
Analisis Biayariil Dan Kesesuaian Dengan Tarif INA-CBG’S Pada Pasien Kanker Kolorektal Di RSUD Dr. Moewardi Surakarta Tahun 2018
Authors: Amalia Annora Rizky
Published: February 2022

Kanker kolorektal adalah kanker yang dimulai dari bagian kolon atau rectum. Kanker kolorektal terjadi ketika tumor terbentuk pada lapisan usus besar. Tingginya biaya riil kemoterapi kanker kolorektal merupakan faktor utama dibuatnya program jaminan kesehatan nasional melalui paket INA-CBG’s. Tujuan penelitian untuk mengetahui kesesuaian biaya riil dengan tarif paket INA-CBG’s dan faktor-faktor yang mempengaruhi biaya riil pada pasien kanker kolorektal rawat inap di RSUD Dr. Moewardi Surakarta.

Penelitian ini menggunakan metode observational crosssectional. Data diambil secara retrospektif. Subyek dan obyek penelitian ini adalah pasien kanker kolorektal yang menjalani rawat inap dan data rekam medik serta berkas klaim pelayanan rawat inap di RSUD Dr. Moewardi Surakarta periode Januari-Desember 2018. Lokasi penelitian dilakukan di RSUD Dr. Moewardi Surakarta. Analisis yang digunakan adalah one sample t-test untuk mengetahui kesesuaian antara biaya riil dan tarif INA-CBG’s serta analisis korelasi bivariat untuk mengetahui hubungan biaya riil dengan faktor-faktor yang mempengaruhi biaya riil.

Hasil penelitian menunjukkan bahwa pada prosedur intestinal kompleks (K-1-20-I/II/III) memiliki rata-rata biaya yang lebih tinggi daripada prosedur yang lain yaitu sebesar Rp 20.889.414,64. Hal ini dikarenakan tingginya biaya pada tindakan medis dan juga biaya farmasi. Berdasarkan besarnya perbedaan antara tarif riil dengan paket INA-CBG’s pada pasien kanker kolorektal di RSUD Dr. Moewardi Surakarta tahun 2018 prosedur yang memiliki selisih biaya paling tinggi adalah pada prosedur kemoterapi pada tingkat keparahan C-4-13-I dengan total selisih sebesar Rp -671.021.073,14 (selisih negatif).  Faktor yang paling berpengaruh adalah Length Of Stay (LOS) pada prosedur anal dengan kode INA-CBG’s K-1-50 dengan nilai p <0,05 (0,000) dan pada prosedur tumor pencernaan dengan kode INA-CBG’s K-4-10 dengan nilai p<0,05 (0,001).
Formulasi Hair Tonic dari Ekstrak Etanol, Fraksi Etanol, dan Fraksi Kloroform-Metanol Kayu Secang (Caesalpinia sappan L.)
Authors: Sari Dina Yuspita , Widyasari Ratna , Puspita Weni
Published: February 2022

Kayu Secang (Caesalpinia sappan L.) dimanfaatkan sebagai antioksidan pada produk kosmetik. Beberapa kandungan senyawa di dalamnya adalah brazilin, brazilein, 3´-O-metilbrazilin, sappanon, kalkon, dan sappankalkon sebagai metabolit sekunder yang berpotensi sebagai antioksidan. Penelitian ini bertujuan untuk memformulasi hair tonic dari ekstrak dan fraksi kayu secang, menentukan kualitas, dan aktivitas pertumbuhan rambut formula hair tonic menggunakan ekstrak etanol (Eet), fraksi etanol (Fen), dan fraksi kloroform-metanol (Fkm) kayu secang.

Simplisia kayu secang dimaserasi menggunakan etanol 96 %, kemudian dipartisi menggunakan n-heksana. Fraksi etanol selanjutnya diaplikasikan menggunakan kromatografi kolom vakum (KKV) menggunakan eluen kloroform, kloroform:metanol (5:1), dan kloroform. Eet, Fen, dan Fkm kayu secang kemudian diformulasi ke dalam sediaan hair tonic. Evaluasi hair tonic meliputi pengujian organoleptis, penentuan pH, penentuan viskositas, pengujian homogenitas, dan pengujian aktivitas pertumbuhan rambut.

Hasil penelitian menunjukkan bahwa ketiga formula hair tonic menghasilkan warna merah-jingga, berbau aromatik dengan bentuk cair/larutan, memiliki pH 7, homogen, dan viskositas 3 cps. Ketiga formula hair tonic memberikan aktivitas pertumbuhan rambut kelinci pada parameter panjang rambut dan bobot rambut. FIII yang mengandung fraksi kloroform-metanol kayu secang memberikan hasil berbeda bermakna dengan kontrol negatif pada data panjang rambut kelinci hari ke 30 yang menunjukkan bahwa FIII memberikan aktivitas terbaik. Ketiga formula memenuhi persyaratan mutu hair tonic dan memberikan aktivitas pertumbuhan rambut.
Literature Review: Aktivitas Batang dan Daun Sambiloto (Andrographis Paniculata Nees) terhadap Target Molekular Terapi Diabetes
Authors: Mar'ah Nurul Hidayatul
Published: February 2022

Andrographis paniculata Nees, disebut juga sambiloto adalah tanaman yang berkhasiat sebagai terapi alternatif diabetes melitus (DM). Sambiloto merupakan tanaman multi-compounds yang memiliki kandungan senyawa antara lain: diterpenoid, flavonoid dan polifenol. Studi ini bertujuan menjelaskan aktivitas senyawa kimia yang terkandung di dalam batang dan daun sambiloto terhadap lima target molekular terapi DM, yaitu Dipeptidyl Peptidase 4 (DPP4), Protein Tyrosine Phosphatase (PTP1B), α-glukosidase, Glucose Transporter (GLUT) dan glukokinase.

Studi ini menggunakan metode systematic review, yakni dengan membuat PRISMA checklist dan diagram flow, menetapkan kriteria inklusi-eksklusi, search engine serta kata kunci untuk mendapatkan data yang relevan. Data yang diperoleh berupa hasil penelitian primer yang disajikan dalam tabel ekstraksi data, selanjutnya ditelaah secara komprehensif.

Hasil studi menunjukkan bahwa golongan senyawa diterpenoid dan flavonoid yang terkandung dalam batang dan daun sambiloto dapat memberikan aktivitas terhadap target molekular, seperti senyawa 19-trifenil isoandrografolid dapat menghambat DPP4, α-glukosidase dan mengaktivasi glukokinase; senyawa andrografolakton dapat menghambat PTP1B; senyawa deoksiandrografolid meningkatkan translokasi dan akselerasi GLUT4; senyawa 15-p-metoksibenziliden 14-deoksi-11,12-didehidroandrografolid menghambat α-glukosidase; dan Golongan flavonoid seperti senyawa apigenin mampu menghambat DPP4, PTP1B, serta mengaktivasi glukokinase.
Coagulopathy complicating intraoperative blood salvage in patients receiving cesarean section: three case reports and a literature review
Authors: Zhang Yang , Gu Wei-Rong , Xiao Xi-Rong
Published: February 2022

Background: Intraoperative cell salvage (ICS) has been used in more than 1100 published obstetrics cases and can reduce the need for allogeneic transfusion effectively. However, ICS could lead to a life-threatening coagulopathy called salvaged blood syndrome (SBS). SBS was reported in several non-obstetric cases but has rarely been reported in obstetric patients. Cases: We reviewed all 841 cell savage cases that occurred in our hospital prior to October 2018. Here, we present 3 cases of coagulopathy in patients who received ICS after cesarean section. The rate of obstetrical SBS in our hospital was 0.46%. Dicussion: Cesarean section was performed without severe hemorrhage, and we performed the surgical hemostatic procedures as usual. Then, several hours after the surgery and after ICS, bleeding occurred, in which hypofibrinogenemia was more severe than expected based on the amount of postpartum hemorrhage. In addition, other marked changes in coagulation function-related parameters, including a decline in the platelet count and obvious prolongation of the PT and aPTT levels, were also observed. More specific and in-depth studies concerning obstetric SBS are needed.
Accuracy of office hysteroscopy in the diagnosis of chronic endometritis
Authors: Abdel Moneim Mohamed Elmahdy , Latif Amany Abdelbary Abdel , Shehata Marwa Said , Ghanem Ibrahim Abdel Latif
Published: February 2022

Background: To test the accuracy of office hysteroscopy in the diagnosis of chronic endometritis (CE) as compared to histopathological diagnosis. Methods: This prospective cohort study was conducted in a private hospital from July 2018 to January 2020. 220 infertile women were scheduled for first attempt of intracytoplasmic sperm injection (ICSI). Patients ranging in age from 20–40 with history of primary infertility scheduled for ICSI for the first time were included, while patients with chronic diseases, severe vaginal bleeding, previous failed ICSI, polycystic ovary syndrome (PCOS), or endometriosis were excluded. All patients received postmenstrual office hysteroscopy to rule out the presence of CE; at the same setting, endometrial biopsy was taken and sent for histopathological examination. Results: 174 cases (79.1%) were diagnosed as CE at hysteroscopy, while 162 (73.6%) cases were positive at histopathology. 99.4% of the cases presented with hyperaemia, followed by oedema in 74.7% and micro-polypi in 58.6% of cases with CE. There was a significant difference between the hysteroscopic and the histopathologic diagnosis of CE (p < 0.001). The sensitivity, specificity, and positive and negative predictive values of hysteroscopy were 93.83%, 62.07%, 87.36% and 78.26% respectively. Conclusions: Office hysteroscopic evaluation is relatively accurate on its own but can be further confirmed by CD138 staining.
Is ovarian cystectomy feasible for patients with borderline ovarian tumors? A retrospective study and review of the literature
Authors: Kim Seongmin , Min Kyung Jin , Lee Sanghoon , Hong Jin Hwa , Song Jae Yun , Lee Jae Kwan , Lee Nak Woo
Published: February 2022

Background: Given that borderline ovarian tumors (BOTs) are usually found in young, fertile women without a history of childbirth, fertility preservation should be considered in the treatment plan. This retrospective study aimed to evaluate the safety of ovarian cystectomy in patients with BOTs. Methods: Patients with BOTs treated between August 2007 and August 2016 at our institution were divided into two groups according to the type of surgery: the cystectomy group and the oophorectomy group with or without salpingectomy, and differences in surgical outcomes were compared. The cumulative disease recurrence was also compared using Kaplan–Meier curves. Results: Of the 162 patients enrolled, 128 (79.0%) underwent an oophorectomy with or without salpingectomy and 34 (21.0%) underwent an ovarian cystectomy. The patients in the cystectomy group were younger than those in the oophorectomy group (29.2 years vs. 46.5 years, p < 0.001), and the proportion of patients who underwent minimally invasive surgery was higher in the cystectomy group than in the oophorectomy group (88.2% vs. 46.9%, p < 0.001). During the mean follow-up period of 44 months, six patients (3.70%) developed disease recurrence (five [3.9%] and one [2.9%] in the oophorectomy and cystectomy groups, respectively). The two-year disease-free survival rate was 97.1% and 97.6% in the cystectomy and oophorectomy groups, respectively, and did not differ between the groups (p = 0.818). Discussion: Ovarian cystectomy can be considered a safe and effective option for young women with BOTs who wish to preserve their fertility.