bluuebunny/crossref_metadata_2025 huggingface dataset:
How Health Professionals Identify and Respond to Perpetrators of Domestic and Family Violence in a Hospital Setting: A Scoping Review
Authors: Schalk Danielle , Fernandes Christina
Published: April 2024

There is heightened awareness that a whole-of-systems approach to perpetrator responses is key to addressing domestic and family violence (DFV). This paper reports on the findings from a scoping review which mapped the international literature on how health professionals identify and respond to perpetrators of DFV within a hospital setting. A comprehensive scoping review methodology was used. The search, spanning January 2010 to January 2022, yielded 12,380 publications from four databases. Eligibility for inclusion included peer-reviewed literature with any reference to inpatient hospital health professionals identifying or responding to perpetrators of DFV. Fourteen articles were included in the final review. The review presents the literature categorized by levels of prevention, from primary, secondary, through to tertiary preventive interventions. An additional category “other practices” is added to capture practices which did not fit into existing levels. Despite glimpses into how health professionals can identify, and respond to perpetrators of DFV, the current knowledge base is sparse. The review did not identify any mandated or formal procedures for identifying and/screening or responding to perpetration of abuse in hospitals. Rather, responses to perpetrators are inconsistent and rely on the motivation, skill, and self-efficacy of health professionals rather than an embedded practice that is driven and informed by hospital policy or procedures. The literature paints a picture of missed opportunities for meaningful work with perpetrators of DFV in a hospital setting and highlights a disjuncture between policy and practice.
Preparation and properties of shape memory polyurethane filaments triggered by human body temperature
Authors: Wan Ailan , Wang Xiaoxiao , Zeng Deng , Qi Qian
Published: April 2024

To utilize the human body heat to trigger the shape memory smart textiles, shape memory polyurethane filaments (SMPUF) with three different transition temperatures were prepared based on modified polycaprolactone diol (PCL) by dry spinning. The chemical structure was characterized systemically. The shape memory properties, tensile properties, resilience, and viscoelasticity were studied comprehensively. The results revealed that the phase transition temperatures were close to human body temperature which measured 19.97°C, 27.33°C, and 30.37°C, respectively. Additionally, the fraction of hydrogen bonds in the samples was about 30% less than that of polyurethane filaments (PUF). The best shape fixity ratio was 88.5% and the shape recovery ratio was 96.7% belonging to samples with a transition temperature of 30.37°C. At 55°C, the elastic recovery was 45.2% higher than that at 22°C. As the temperature rose, the elastic modulus of SMPUF decreased until it reached that of PUF. The static and dynamic viscoelasticity of SMPUF indicated that the phase transition of the soft segment affects the movement of the molecular chain. SMPUF can be used as compression garments, and wearable orthopedic devices, such as the elastic bands prepared in this work.
Occupational Therapy and Imprisoned Adolescents: An Analysis of Professional Practices
Authors: Oliveira Renata Hoeflich Damaso de , Malfitano Ana Paula Serrata
Published: April 2024

The care of adolescents in reclusion has been a field of work for occupational therapists in different parts of the world. The objective of this study was to describe and analyze Brazilian occupational therapists’ practices with adolescents in reclusion. Research conducted in Brazil, identifying 56 professionals, invited to answer a questionnaire ( n = 43); participate in discussion groups ( n = 9); and interview ( n = 4). Professionals reported different visions that guide their practices, including the identification of individual skills and the profession’s possibilities for social action. Occupational therapists have specificities to work in these institutions, highlighting the possibilities of acting with a focus on social change. Practices in occupational therapy can lead to social change if focused on social issues. Social occupational therapy offers theoretical and methodological elements that inform the profession. Reflections on the practice carried out, according to a critical perspective, enable a performance in occupational therapy that intends social change.
Minimally Invasive Treatment of Pelvic Fractures with Titanium Elastic Nailing: An Innovative Technology
Authors: Jia Zhaofeng , Qin Hanjun , Lin Jiandong , Wang Xin , Bai Ruochen , Zou Suying , Huang Wenjun , Hu Xinjia
Published: April 2024

Background

Minimally invasive treatment has become the most popular and effective treatment for pelvic fractures. This study aimed to evaluate the safety and efficacy of a new technique, titanium elastic nailing (TEN), for the minimally invasive treatment of pelvic fractures.

Method

Twenty-four patients with pelvic fractures were referred to us between January 2020 to January 2022, including sixteen males and 8 females. Pelvic fractures were temporarily fixed by pelvic fixation belt accompanied by traction from the lower limb bone. Anterior pelvic ring injuries (superior ramus of pubis) and ilium fractures were treated with closed reduction and intramedullary fixation with minimally invasive TEN. Intraoperative C-arm, including pelvic anteroposterior, pelvic outlet, inlet and ilium oblique views, and O-arm fluoroscopy (intraoperative CT) were employed to assess fractures reduction and determine the location of the elastic titanium nail within the bone channel.

Results

By adopting closed reduction and minimally invasive incision techniques, pelvic fractures could be safely fixed by placing an elastic titanium nail in the osseous medullary cavity channels of the pelvis. Postoperative investigation indicated that the wounds of all patients were healed in the first stage without any occurrence of complications, such as injuries to the nerves, blood vessels, and important tissue structures. Patients are essential quickly after the operation and could perform the functional exercise in the early stages of the recovery.

Conclusion

TEN can be used for minimally invasive treatment of pelvic fractures. This novel technique has no obvious complications and is worthwhile in clinical practice.
Examining the Economic Value of Collegiate Club Sports to the University
Authors: Li Zikun , Chalip Laurence , Rodgers Ellen B. Drogin
Published: April 2024

To measure the contribution of collegiate club sports to the economic and social environment of higher education institutions, this case study developed a pragmatic model—integrating self-generated revenue, stimulated student spending, student attraction, and student retention—to quantify the economic value or worth of club sports to the university, and to consider their broader utility for the attainment of the university's mission. For the university studied, results show that undergraduate club sport athletes render approximately $21.7 million in institutional expenditure annually, and club sports can serve the university mission through their contribution to student recruitment, retention, and recommendation. Over 50% of participants credited their enrollment, continued attendance, and willingness to recommend the university to the availability of club sports. Student retention was more positive for participants in club sports than for the university population as a whole. Additionally, international students and students living off-campus viewed club sports as particularly positive.
A semi-analytical strategy for mixed convection non-Newtonian nanofluid flow on a stretching surface using Cattaneo-Christov model
Authors: Mumtaz Muhammad , Islam Saeed , Ullah Hakeem , Dawar Abdullah , Shah Zahir
Published: April 2024

This study investigates flow of non-Newtonian fluid containing nano particles and gyrotactic micro-organisms on stretching surface considering magnetic factor and thermal radiations. Cattaneo-Christov model is employed to analyze flow characteristics. The governing Partial Differential Equations (PDEs) along with associated boundary conditions describing the model are converted into Ordinary Differential Equations (ODEs) by suitable transformations. Homotopy Analysis Method (HAM), a semi-analytic solution technique is employed to obtain the solutions. The inspiration of important embedding variables on velocity, temperature, and concentration profiles are presented in tabular and graphical form to elaborate flow properties. It is deduced that the convective parameter and Weissenberg number, both have positive effect on dimensionless velocity whereas buoyancy ratio factor, bio-convective Rayleigh number, and magnetic force have inverse relationship with velocity profile. The presence of radiations and Brownian motion parameter boost energy transfer while it diminishes for higher Prandtl number values and mixed convection factor. Concentration intensifies for larger Prandtl number, activation energy, and thermophoresis parameters whereas it decreases for increasing temperature difference, Brownian motion, Schmidt number, and mixed convection factor. Bio-convective Peclet number, Lewis number, and microorganism concentration gradient factor, all depreciate microorganism concentration panel.
Critical importance of correctly defining and reporting secondary endpoints when assessing the ethics of research biopsies
Authors: Levit Laura A , Garrett-Mayer Elizabeth , Peppercorn Jeffrey , Ratain Mark J
Published: April 2024

This article reviews the implementation challenges to the American Society of Clinical Oncology’s ethical framework for including research biopsies in oncology clinical trials. The primary challenges to implementation relate to the definitions of secondary endpoints, the scientific and regulatory framework, and the incentive structure that encourages inclusion of biopsies. Principles of research stewardship require that the clinical trials community correctly articulate the scientific goals of any research biopsies, especially those that are required for the patient to enroll on a trial and receive an investigational agent. Furthermore, it is important to sufficiently justify the characterization of secondary (as distinguished from exploratory) endpoints, protect the interest of research participants, and report accurate and complete information to ClinicalTrials.gov and the published literature.
Law as Mnemonic Infrastructure: Archival Legal Discourses and Memory Battles in Romania
Authors: Şerban Mihaela
Published: April 2024

This article examines law as mnemonic infrastructure, tracing how archival laws and policies in Romania shape the construction of its collective memory of communism and fascism. The four layers analyzed here—archival institutions, norms, processes, and practices—help produce a memory regime characterized by nationalism, the securitization of historical memory, and a selectively amnesic collective memory. Focusing on law as mnemonic infrastructure highlights indirect and structural pathways in the construction of memory regimes, with distinctive, if not always obvious, knowledge and truth effects that help clarify the role of law in promoting or undermining hegemonic memory regimes.
Animal behaviour and welfare research: A One Health perspective
Authors: Yeates James William
Published: April 2024

Animal behaviour and welfare research are part of a wider endeavour to optimize the health and wellbeing of humans, animals and ecosystems. As such, it is part of the One Health research agenda. This article applies ethical principles described by the One Health High Level Expert Panel to animal behaviour and welfare research. These principles entail that animal behaviour and welfare research should be valued equitably alongside other research in transdisciplinary and multisectoral collaboration. It should include and promote a multiplicity of marginalized voices, including those of animals, and it should apply and describe a harmonious balance between human—animal-environment interactions. Lastly, it should describe how humans need to change behaviour, adopt sustainable solutions and recognize the importance of animal welfare and the integrity of the whole ecosystem.
Hemophagocytic lymphohistiocytosis in pregnancy—a case report
Authors: Fahad Asma , Hazari Komal , Fazari Atif
Published: April 2024

Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening condition that is a rare occurrence in pregnancy and can be elusive in its diagnosis thereby delaying treatment. We report the case of a 30-year-old female patient at 36 weeks of pregnancy who presented with a persistent fever that did not respond to antibiotics. After we investigated her thoroughly, considering the persistent fever, we performed a bone marrow biopsy as part of the workup for prolonged pyrexia. We diagnosed her with HLH secondary to cytomegalovirus pneumonia. As her laboratory investigations fulfilled the criteria for HLH we treated her with the appropriate therapy using a multidisciplinary approach, resulting in her complete recovery. HLH should be considered a potential differential diagnosis in pregnant patients complaining of persistent fever, cytopenia, or declining clinical condition despite delivery of the baby.
Navigating brain drain in the Western Balkans
Authors: Jansen Lien , Bernstein Lune , Van Hecke Steven
Published: April 2024

This article analyses the European Commission’s attitude vis-à-vis labour migration and brain drain in the Western Balkans. It uses Croatia’s post–EU accession experience as a focal point. Grappling with elevated migration rates and a decline in natality, the Western Balkan countries are an interesting region in terms of demographic change. Examining how much attention the Commission pays to brain drain, the article notes an increase since 2019; yet this focus appears disproportionately limited considering the potential repercussions for economic growth and social welfare in the countries experiencing it. The Commission’s predominantly negative view of brain drain emphasises that it is the nations affected that are responsible for avoiding it, thereby confirming that it is caused by a skills mismatch. The article recommends integrating brain-drain prevention measures into the enlargement process, and encourages the Commission to improve its focus on the matter in its annual candidate and potential candidate country progress reports.
UPLC-Q-TOF-MS Analysis of Chemical Constituents of the Kadsura coccinea Extract with Effect of Attenuating Lipid Accumulation in Vitro
Authors: Gu Tiancheng , Liu Wei , Wang Laiyou , Cheng Jisheng
Published: April 2024

Objective/Background: This study aims to explore the Kadsura coccinea extract (KCE)'s effect on lipid accumulation in vitro and its chemical components characterizations, aiming at developing a new alternative plant medicinal resource to fight against non-alcoholic fatty liver disease (NAFLD). Methods: After toxicological evaluation of KCE on HepG2 cells, Oil red O staining model and intracellular TGs quantification kit were used to examine the effects of KCE on lipid accumulation in vitro. The chemical components characterizations and potential active chemical constituents of the bioactive KCE were analyzed using ultra-high-performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UPLC-Q-TOF-MS) technology. Results: Among the chosen non-toxic concentrations of KCE (5, 10, 20 μg/mL), KCE can reduce the number and volume of lipid droplets in the oleic acid induced HepG2 cells in a dose-dependent manner, and the results of TGs quantification were almost consistent with the results of the oil red O staining experiment. These data indicate the KCE has ameliorative effect on lipid accumulation in vitro. In addition, a total of 26 compounds from the KCE were tentatively identified, dibenzocyclooctadiene lignans (DCLs) including Kadsulignan L and Gomisin J could be the main supposed components. Conclusion: These findings support further investigation into Kadsura coccinea containing DCLs as a new alternative medicinal arsenal to battle against NAFLD.
Why Scholars and Students Should Write Book Reviews
Authors: Crocco Oliver S. , Zarestky Jill
Published: April 2024

It is common within academia to hear that scholars and students should avoid writing book reviews. They are not peer-reviewed, can take a lot of time, and are often considered less prestigious than other forms of academic publishing. However, we make the case—as two scholars with experience as Book and Media Editors––that not only are book reviews a legitimate and important form of academic publishing, but the many benefits of writing book reviews outweigh the reasons for avoiding them. These benefits include having access to cutting-edge books, honing one’s skill in scholarly synthesis and communication, gaining experience with the academic publishing process, and providing service to one’s academic field. In this Writer’s Forum, we illuminate these and more reasons for doing book reviews and encourage readers of all stages of their academic careers to consider writing book reviews.
Diabetic ketoacidosis with central nervous system involvement: Conventional and advanced magnetic resonance neuroimaging findings
Authors: Caschera Luca , Fiore Giorgio , Nava Simone , Criscuolo Stefania , Lo Russo Francesco M , Casale Silvia , Conte Giorgio , Platania Giulia , Costa Antonella , Carrabba Giorgio , Locatelli Marco , Triulzi Fabio Maria
Published: April 2024

Diabetic ketoacidosis (DKA) is a serious complication in children with diabetes mellitus type 1 (DM1). In rare and severe cases DKA may be complicated by cerebral edema, central brain herniation and cerebral infarctions. We present the magnetic resonance imaging findings in a child with DKA and central nervous system involvement; diffusion tensor imaging (DTI) and functional MRI (fMRI) were performed to assess the white matter integrity of sensory pathways and cortical sensory processing. Conventional imaging showed bilateral uncal herniation, effacement of the perimesencephalic cisterns, wide ischemic lesions in the posterior cerebral artery (PCA) territories, sagging brainstem and Duret’s hemorrhage consistent with signs of central brain herniation and intracranial hypertension. Advanced MRI showed a possible left-sided cortical reorganization for sensory function, with underlying left cortico-talamic and cortico-spinal pathways less severely impaired. Knowledge of the full framework in these conditions is of vital importance for timely patient management; advanced neuroimaging techniques may be considered as prognostic indicators in those cases with extensive involvement of eloquent brain areas.
Endoscopic management of a transgastric migrated gossypiboma: A case report
Authors: Achemlal Amine , Nejjari Fouad , Jidal Manal , Taibi Ouiam , Berrag Sanaa , Adioui Tarik , Tamzaourte Mouna
Published: April 2024

Textiloma, also known as gossypiboma, is a rare but well-documented entity. It involves the omission of surgical material during surgery. Gossypiboma remains a diagnostic dilemma to this day, due to its wide spectrum of clinical symptoms and numerous radiological pitfalls. The recommended treatment for gossypiboma is surgical removal. Endoscopic removal has been performed by some teams and has shown satisfying results. We report the case of a 33-year-old woman with a transgastric migrating gossypiboma, managed by an endoscopic extraction.
How institutional logics shape the adoption of virtual reality in mental health care: A qualitative study
Authors: Terkildsen Morten D , Bollerup Stina , Palmhøj Camilla , Jensen Lotte G , Lou Stina
Published: April 2024

Objective

To analyse institutional logics’ role in adopting virtual reality in mental health care.

Methods

Data were collected via qualitative, semi-structured interviews with four frontline staff and seven administrative and service staff, two focus group interviews with three frontline staff and four administrative and service staff, and via participant observation in meetings between stakeholders working on virtual reality. Data were collected from May 2021 to February 2022, analysed using thematic analysis, and theoretically driven by the framework of Institutional logics.

Results

We identified two different forms of institutional logics being drawn upon by frontline staff and administrative and service staff, respectively, when working with the adoption of virtual reality in mental health care. Frontline staff drew mainly on a Professional logic; administrative and service staff drew on a Diffusion logic. Each logic defined a unique focal point, causal pathway, and perceptions of a meaningful adoption process for virtual reality.

Conclusions

By taking institutional logics as our theoretical and analytical point of departure, this study demonstrates how the meaning of virtual reality and its adoption in mental health care is grounded in multiple and sometimes conflicting institutional logics. Acknowledging the existence and influence of often multiple institutional logics in the adoption process is crucial to guide the future adoption of virtual reality in mental health care. Organising collaborative venues for stakeholders where their multiple institutional logics are made the subject of joint reflection is essential to counter frictions.
Positive harmonisation of national criminal law: Necessary or essential for mutual recognition?
Authors: Rus Andrei Claudiu , Jderu Claudia
Published: April 2024

Positive harmonisation of criminal law should only be a subsidiary means of implementing the principle of mutual recognition. Regarding criminal procedural law, this is laid down in Art. 67 TFEU (‘if necessary’) and in Art. 82(2) TFEU (‘to the extent necessary’). However, the effectiveness of the principle of mutual trust depends on the harmonisation of the national laws of the Member States, especially in cases when the national law of the executing State does not regulate at all aspects that may affect the nature or aggravate the sentence which is to be recognised. In this context, we will try to show that, if the alternative execution modality of a custodial sentence is not at all regulated in the national law of the executing State, its recognition and enforcement, with the consequent continuous deprivation of liberty of the sentenced person, could be considered an aggravation of the sentence and thus a violation of Article 8(4) of FD 2008/909. The paper thus highlights not only the differences between the legal frameworks of some Member States, but also how the lack of regulation on alternative execution modalities to custodial sentences or probation measures and alternative sanctions could stand in the way of reaching the purposes of Framework Decisions 2008/909 and 2008/947. On the other hand, we will show that although the framework decisions cannot have a direct effect, when applying national law, the national authorities are therefore required to interpret it, to the greatest extent possible, in light of the text and the purpose of the framework decision in order to achieve the result sought by that decision.
Focusing on Positive Listening Experiences Improves Speech Intelligibility in Experienced Hearing Aid Users
Authors: Lelic Dina , Nielsen Line Louise Aaberg , Pedersen Anja Kofoed , Neher Tobias
Published: April 2024

Negativity bias is a cognitive bias that results in negative events being perceptually more salient than positive ones. For hearing care, this means that hearing aid benefits can potentially be overshadowed by adverse experiences. Research has shown that sustaining focus on positive experiences has the potential to mitigate negativity bias. The purpose of the current study was to investigate whether a positive focus (PF) intervention can improve speech-in-noise abilities for experienced hearing aid users. Thirty participants were randomly allocated to a control or PF group (N = 2 × 15). Prior to hearing aid fitting, all participants filled out the short form of the Speech, Spatial and Qualities of Hearing scale (SSQ12) based on their own hearing aids. At the first visit, they were fitted with study hearing aids, and speech-in-noise testing was performed. Both groups then wore the study hearing aids for two weeks and sent daily text messages reporting hours of hearing aid use to an experimenter. In addition, the PF group was instructed to focus on positive listening experiences and to also report them in the daily text messages. After the 2-week trial, all participants filled out the SSQ12 questionnaire based on the study hearing aids and completed the speech-in-noise testing again. Speech-in-noise performance and SSQ12 Qualities score were improved for the PF group but not for the control group. This finding indicates that the PF intervention can improve subjective and objective hearing aid benefits.
Risk Factors for Birth Asphyxia in Hospital-Delivered Newborns in Dodoma, Tanzania: A Case-Control Study
Authors: Msisiri Laidi S. , Kibusi Stephen M. , Kimaro Franisca D.
Published: April 2024

Introduction

Asphyxia at birth remains the leading cause of neonatal morbidity and mortality worldwide, accounting for ∼23% of all neonatal deaths. Although the causes vary from country to country, early identification and treatment of risk factors can improve the situation.

Objectives

To determine the risk factors of birth asphyxia in hospital-delivered neonates in Dodoma, Tanzania.

Methods

A matched case-control study was conducted from May to July 2017 at Dodoma Region Referral Hospital. Data were collected using a semistructured questionnaire and a standard antenatal care index card. Cases were neonates diagnosed with asphyxia at birth ( N  =  100), while controls were neonates not diagnosed with asphyxia at birth ( N  =  300). A binary logistic regression model was used to assess the independent variables associated with birth asphyxia and reported as crude and adjusted odds ratios along with their 95% confidence intervals.

Results

A total of 400 newborns and their birth mothers were involved in the study. The average age of the case mothers was 26.9 years ( SD  =  7.85) and that of the control mothers was 27.24 years ( SD  =  6.08). Place of residence, anemia, maternal age, prenatal visits attended, use of herbs during labor, previously complicated pregnancy, duration of labor, meconium-stained amniotic fluid, and mode of delivery were predictors of birth asphyxia.

Conclusion

The study showed that most predictors of birth asphyxia can be prevented. The results suggest appropriate health education before conception, effective follow-up through prenatal care, early identification and treatment of high-risk pregnant women, and proper monitoring of labor and delivery.
Gain and loss cycles revisited: What to consider when testing key assumptions of conservation of resources theory
Authors: Sonnentag Sabine , Meier Laurenz L.
Published: April 2024

In this editorial, we discuss approaches to the empirical test of gain and loss cycles as described within Hobfoll's conservation of resources theory (COR). We present COR theory's basic assumptions about gain and loss cycles and critically discuss typical empirical studies that aim at testing these assumptions. We highlight conceptual and empirical problems when testing gain and loss cycles of resources and provide guidance for researchers with respect to theoretical, temporal, and data-analytic aspects. We offer some suggestions for constructive replications and reproducibility.
How transportability analysis can be useful for cumulative theory testing in management research
Authors: Lee Gwendolyn Kuo-Fang
Published: April 2024

Moving management science forward by publishing research aimed at theory testing and refinement is the mission of the Journal of Management Scientific Reports. One way to test and refine a theory is through constructive replication studies. If X→Y (the causal effect of X on Y) is found in an initial study, what assumptions and mechanisms are required to expect that X→Y would also be found in a subsequent study, when the population differs between the initial and subsequent studies? What structural discrepancies between source and target populations would render transporting the knowledge obtained from one study to another impossible? Whereas generalizability is concerned with making inferences based on a possibly biased sample drawn from a focal population about the focal population, transportability refers to the conditions under which a transfer of causal knowledge across populations is valid. Researchers now have access to methods for identifying the conditions under which causal information learned from experiments would be valid in studies where ideal experiments cannot be conducted and where only passive observations can be collected. In this commentary, I explain how transportability analysis and its associated diagnostic tools from machine learning and artificial intelligence can be useful for cumulative theory testing in management research.
Electrothermal Model Based Remaining Charging Time Prediction of Lithium-Ion Batteries against Wide Temperature Range
Authors: Xiong Rui , Zhao Zian , Chen Cheng , Li Xinggang , Shen Weixiang
Published: April 2024

Battery remaining charging time (RCT) prediction can facilitate charging management and alleviate mileage anxiety for electric vehicles (EVs). Also, it is of great significance to improve EV users' experience. However, the RCT for a lithium-ion battery pack in EVs changes with temperature and other battery parameters. This study proposes an electrothermal model-based method to accurately predict battery RCT. Firstly, a characteristic battery cell is adopted to represent the battery pack, thus an equivalent circuit model (ECM) of the characteristic battery cell is established to describe the electrical behaviors of a battery pack. Secondly, an equivalent thermal model (ETM) of the battery pack is developed by considering the influence of ambient temperature, thermal management, and battery connectors in the battery pack to calculate the temperature which is then fed back to the ECM to realize electrothermal coupling. Finally, the RCT prediction method is proposed based on the electrothermal model and validated in the wide temperature range from − 20 ℃ to 45 ℃. The experimental results show that the prediction error of the RCT in the whole temperature range is less than 1.5%.
Health-related quality of life, work ability and disability among individuals with persistent post-dural puncture headache
Authors: Kapan Ali , Waldhör Thomas , Schiffler Tobias , Beck Jürgen , Wöber Christian
Published: April 2024

Background and objectives

Postdural puncture headache (PDPH) is an acknowledged consequence of procedures like lumbar punctures, epidural analgesia, and neurosurgical interventions. Persistence over more than three months, however has been poorly studied. In particular, little is known about the impact of persistent PDPH (pPDPH) on health related quality of life (HRQoL), disability and ability to work. The study aimed to provide a holistic understanding of pPDPH, encompassing medical, physical and psychological aspects.

Methods

We conducted a cross-sectional anonymous online survey in individuals aged 18 or older, diagnosed with, or suspected to have pPDPH via self-help groups on Facebook. Participants completed a structured questionnaire covering diagnosis, symptoms, and the ability to work. For assessing headache related disability, and mental health, they filled in the Henry Ford Hospital Headache Disability Inventory (HDI) and the Depression Anxiety Stress Scale-21 (DASS-21).

Results

A total of 179 participants (83.2% female, mean age 39.7 years) completed the survey. PPDPH had been present for one year or more in 74.3%, and 44.1% were unable to be in an upright position for more than one hour per day without having to lie down or sit down. Headaches were extremely severe or severe in 18% and 34%, respectively. According to the HDI, 31.8% of participants had mild, 25.7% moderate, and 42.5% severe disability. DASS-21 revealed substantial mental health challenges with depression, anxiety and stress experienced by 83%, 98%, and 88% of the respondents. The ability to work was limited considerably: 27.9% were unable to work, 59.8% worked part-time, 1.1% changed their job because of pPDPH, and only 11.2% were able to work full-time in their previous job. Despite treatment, the patients’ condition had deteriorated in 32.4% and remained unchanged in 27.9%.

Conclusion

This study stresses the burden of pPDPH in terms of substantial disability, limited quality of life, mental health concerns, and significant impact on the ability to work. The study highlights the long-term impact of pPDPH on individuals, emphasizing the need for timely diagnosis and effective treatment. It underscores the complexity of managing pPDPH and calls for further research into its long-term effects on patient health and HRQoL.
Impact of COVID-19 on essential healthcare services at the primary healthcare level in Armenia: a qualitative study
Authors: Hayrumyan Varduhi , Abrahamyan Arpine , Harutyunyan Arusyak , Libaridian Lorky , Sahakyan Serine
Published: April 2024

Background

The COVID-19 pandemic has presented significant global healthcare challenges, particularly impacting the continuity of essential health services in low- and middle-income countries. This study investigates the impact of the COVID-19 pandemic on the utilization and provision of essential health services in Armenia.

Methods

We employed a conventional qualitative study design, conducting semi-structured in-depth interviews (n = 17) within public and private primary healthcare (PHC) facilities in Armenia in 2021. Our study participants encompassed physicians providing specialty services in PHC facilities (e.g. endocrinologists, gynecologists/obstetricians, and pediatricians), regular visitors to PHC facilities (e.g. adults with chronic diseases, parents of children), and policymakers. Thematic analysis was conducted, yielding five emergent categories: mobilization and organization of PHC services during COVID-19; PHC visits during COVID-19; worsening of chronic conditions due to the decline in PHC visits; problems with routine childhood vaccinations; and patient-provider communication challenges.

Results

The number of in-person visits to PHC facilities declined due to adaptations in service delivery, imposed lockdown measures, and the public’s fear of visiting healthcare facilities. Maternal and child health services continued with no major disruptions. PHC providers deliberately limited the number of maternal and child visits to essential antenatal care, newborn screenings, and routine childhood immunizations. Still, children experienced some delays in vaccination administration. The pandemic resulted in a notable reduction in follow-up visits and monitoring of patients with chronic conditions, thereby exacerbating their chronic conditions. Phone calls were the primary method of patient-provider communication during the pandemic.

Conclusions

The COVID-19 pandemic has had a profound impact on the delivery and utilization of essential healthcare services at PHC facilities, especially for those with chronic conditions who needed continuous care. Unified national-level guidance and technical capacity are needed to direct the provision of essential services at the PHC level, promote effective health communication, and implement digital platforms for the uninterrupted provision of essential care during public health emergencies.
“Just pee in the diaper” - a constructivist grounded theory study of moral distress enabling neglect in nursing homes
Authors: Lund Stine Borgen , Malmedal Wenche K. , Mosqueda Laura , Skolbekken John-Arne
Published: April 2024

Background

A growing body of evidence shows that many nursing home residents’ basic care needs are neglected, and residents do not receive qualitatively good care. This neglect challenges nursing staff´s professional and personal ideals and standards for care and may contribute to moral distress. The aim of this study was to investigate how nursing staff manage being a part of a neglectful work culture, based on the research question: “How do nursing home staff manage their moral distress related to neglectful care practices?”

Methods

A qualitative design was chosen, guided by Charmaz´s constructivist grounded theory. The study was based on 10 individual interviews and five focus group discussions (30 participants in total) with nursing home staff working in 17 different nursing homes in Norway.

Results

Nursing staff strive to manage their moral distress related to neglectful care practices in different ways: by favouring efficiency and tolerating neglect they adapt to and accept these care practices. By disengaging emotionally and retreating physically from care they avoid confronting morally distressing situations. These approaches may temporarily mitigate the moral distress of nursing staff, whilst also creating a staff-centred and self-protecting work culture enabling neglect in nursing homes.

Conclusions

Our findings represent a shift from a resident-centred to a staff-centred work culture, whereby the nursing staff use self-protecting strategies to make their workday manageable and liveable. This strongly indicates a compromise in the quality of care that enables the continuation of neglectful care practices in Norwegian nursing homes. Finding ways of breaking a downward spiralling quality of care are thus a major concern following our findings.
Epidemiological variations and trends in glaucoma burden in the Belt and Road countries
Authors: Chen Xiangwu , Zhao Yingxi , Zhang Anjing , Zhou Yanping , Li Min , Cheng Xuelin , Zhao Yajun , Yang Shijia , Zhang Zhaoyu , Li Xiaopan
Published: April 2024

Background

Analyzing the glaucoma burden in "Belt and Road" (B&R) countries based on age, gender, and risk factors from 1990 to 2019 in order to provide evidence for future prevention strategies.

Methods

We applied global burden of disease(GBD) 2019 to compare glaucoma prevalence and Years lived with disabilities (YLDs) from 1990 to 2019 in the B&R countries. Trends of disease burden between 1990 and 2019 were evaluated using the average annual percent change and the 95% uncertainty interval (UI) were reported.

Results

From 1990 to 2019, most B&R countries showed a downward trend in age-standardized prevalence and YLDs (all P < 0.05). Additionally, only the age-standardized YLDs in males of Pakistan has a 0.35% increase (95%CI:0.19,0.50,P < 0.001), and most B&R countries has a decline(all P < 0.05) in age-standardized YLDs in every 5 years age group after 45 years old except for Pakistan(45–79 years and > 85 years), Malaysia(75–84 years), Brunei Darussalam(45–49 years), Afghanistan(70–79 years). Finally, in all Central Asian countries, the age-standardized YLDs due to glaucoma caused by fasting hyperglycemia demonstrated have an increase between 1990 and 2019 (all P < 0.05), but Armenia and Mongolia have a decrease between 2010 and 2019 (all P < 0.05).

Conclusion

The prevalence of glaucoma continues to pose a significant burden across regions, ages, and genders in countries along the "B&R". It is imperative for the "B&R" nations to enhance health cooperation in order to collaboratively tackle the challenges associated with glaucoma.
Control of blood pressure in hypertensive children and adolescents assessed by ambulatory blood pressure monitoring
Authors: Vigraijaroenying Kevalin , Pirojsakul Kwanchai , Katanyuwong Poomiporn , Tangnararatchakit Kanchana , Saisawat Pawaree , Chantarogh Songkiat , Paksi Witchuri , Bunmee Uthen
Published: April 2024

Background

There have been few studies evaluating the control of hypertension (HT) in children. This study aimed to assess the control of HT using ambulatory blood pressure monitoring (ABPM) and to compare the parameters between the uncontrolled HT and controlled HT groups.

Methods

Hypertensive patients aged ≥ 5 years who underwent ABPM to assess the control of HT were enrolled. Demographics, office blood pressure (BP), ABPM, and echocardiographic data were collected. Controlled HT was defined using a BP goal recommended by the 2016 European Society of Hypertension guidelines.

Results

There were 108 patients (64.8% males) with a mean age of 14.3 years and 51.9% had primary HT. Controlled HT was detected in 41.1% and 33.3% by office BP and ABPM, respectively. Based on ABPM, there was a greater prevalence of controlled HT in the primary HT than the secondary HT group (44.6% vs. 21.2%, P = 0.01). In the primary HT group, BMI z-score at the last follow-up had a significant decrease in the controlled HT than the uncontrolled HT group (-0.39 vs. 0.01, P = 0.032). Primary HT was negatively associated with uncontrolled HT by ABPM. In addition, ABPM showed greater sensitivity (77.8% vs. 55.8%) and negative predictive value (80.9% vs. 70.8%) to predict LVH than those of office BP measurement.

Conclusion

Only one-third of patients achieved the BP goal by ABPM and most were in the primary HT group. Weight reduction is an important measure of BP control in patients with primary HT to attenuate the risk of LVH.
Uncovering the extent of dementia prevalence in Iran: a comprehensive systematic review and meta-analysis
Authors: Oshnouei Sima , Safaralizade Mahin , Eslamlou Nazila Farrokh , Heidari Mohammad
Published: April 2024

Background

Dementia is one of the major causes of disability and dependency among older people worldwide. The formation of an aging population in Iran can be associated with societal problems, including age-related disorders such as dementia. This study aimed to estimate the prevalence of dementia& Alzheimer disease in adults aged 60 years or older and it’s its geographical distribution in Iran.

Methods

A systematic review and meta-analysis study included articles published in both English and Persian languages and utilized various databases including: Google Scholar, PubMed, Web of Science, Magiran, and thesis database of medicine universities up to December 2022. The pooled prevalence was calculated using random effects models. The prevalence was reported separately for different geographical locations and types of area sampling, and age adjustment was performed for the selected studies. All statistical analyses were conducted using metaprop package in STATA version 17. The I2 statistic was applied to assess heterogeneity.

Results

The meta-analysis considered nine relevant studies that were carried out up to 2023 in Iran. The study found that the prevalence of dementia in central and east counties was estimated to be 0.14 (95% CI; 0.04–0.31), while in western counties, the prevalence was estimated to be 0.1 (95%CI; 0.01–0.27). The estimated overall crude prevalence of dementia was estimated at 0.14 (95% CI; 0.03–0.31). Estimated prevalence-based health centers sampling and hospital-based studies were 0.02 (95% CI; 0.02–0.03), 0.05 (95% CI 0.06–0.11), respectively. One study used nursing home sampling as the sampling method, and the estimated prevalence was 0.43 (95%CI 0.38–0.49).

Conclusion

This is the first systematic review and meta-analysis of the prevalence of dementia’s disease up to 2023 in Iran. The estimated overall prevalence of dementia is lower than the reported prevalence in European countries and similar to other Asian countries.
Prevalence and nature of workplace bullying and harassment and associations with mental health conditions in England: a cross-sectional probability sample survey
Authors: Bunce Annie , Hashemi Ladan , Clark Charlotte , Stansfeld Stephen , Myers Carrie-Anne , McManus Sally
Published: April 2024

Background

Evidence on workplace bullying and harassment (WBH) in the UK has not used probability-sample surveys with robust mental health assessments. This study aimed to profile the prevalence and nature of WBH in England, identify inequalities in exposure, and quantify adjusted associations with mental health.

Methods

Data were from the 2014 Adult Psychiatric Morbidity Survey, a cross-sectional probability-sample survey of the household population in England. Criteria for inclusion in the secondary analysis were being aged 16–70 years and in paid work in the past month (n = 3838). Common mental disorders (CMDs) were assessed using the Clinical Interview Schedule-Revised and mental wellbeing using the Warwick-Edinburgh Mental Wellbeing Scale. Analyses were weighted. We examined associations between past-year WBH and current CMD using multivariable regression modelling, adjusting for sociodemographic factors. Interaction terms tested for gender differences in associations. The study received ethical approval (ETH21220–299).

Results

One in ten employees (10.6%, n = 444/3838) reported past-year experience of WBH, with rates higher in women (12.2%, n = 284/2189), those of mixed, multiple, and other ethnicity (21.0%, n = 15/92), and people in debt (15.2%, n = 50/281) or living in cold homes (14.6%, n = 42/234). Most commonly identified perpetrators of WBH were line managers (53.6%, n = 244/444) or colleagues (42.8%, n = 194/444). Excessive criticism (49.3%, n = 212/444), verbal abuse (42.6%, n = 187/444), and humiliation (31.4%, n = 142/444) were the most common types. WBH was associated with all indicators of poor mental health, including CMD (adjusted odds ratio [aOR] 2.65, 95% CI 2.02–3.49), and 11 of 14 mental wellbeing indicators, including lower levels of confidence (aOR 0.57, 0.46–0.72) and closeness to others (aOR 0.57, 0.46–0.72). Patterns of association between WBH and mental health were similar in men and women.

Conclusions

These findings reinforce a need for more cohesive UK legislation against WBH; guidance on recognition of bullying behaviours for employees, managers, and human resources, focusing on prevention and early intervention, and increased awareness of the impact of WBH on mental health among health service practitioners. Limitations include reliance on cross-sectional data collected before pandemic-related and other changes in workplace practices. Longitudinal data are needed to improve evidence on causality and the longevity of mental health impacts.
Effects of sodium-glucose cotransporter 2 inhibitors on bone metabolism in patients with type 2 diabetes mellitus: a systematic review and meta-analysis
Authors: Wang Jing , Li Xin , Li Yang , Lei Chen
Published: April 2024

Background

Sodium glucose cotransporter 2 (SGLT2) inhibitors are widely used in type 2 diabetes mellitus (T2DM) therapy. The impact of SGLT2 inhibitors on bone metabolism has been widely taken into consideration. But there are controversial results in the study on the effect of SGLT2 inhibitors on bone metabolism in patients with T2DM. Therefore, we aimed to examine whether and to what extent SGLT2 inhibitors affect bone metabolism in patients with T2DM.

Methods

A literature search of randomized controlled trials (RCTs) was conducted through PubMed, Web of Science, Embase, Cochrane databases, and Scopus from inception until 15 April 2023. Eligible RCTs compared the effects of SGLT2 inhibitors versus placebo on bone mineral density and bone metabolism in patients with T2DM. To evaluate the differences between groups, a meta-analysis was conducted using the random effects inverse-variance model by utilizing standardized mean differences (SMD).

Results

Through screening, 25 articles were finally included, covering 22,828 patients. The results showed that, compared with placebo, SGLT2 inhibitors significantly increased parathyroid hormone (PTH, SMD = 0.13; 95%CI: 0.06, 0.20), and cross-linked C-terminal telopeptides of type I collagen (CTX, SMD = 0.11; 95%CI: 0.01, 0.21) in patients with T2DM, decreased serum alkaline phosphatase levels (ALP, SMD = -0.06; 95%CI: -0.10, -0.03), and had no significant effect on bone mineral density (BMD), procollagen type 1 N-terminal propeptide (P1NP), 25-hydroxy vitamin D, tartrate resistant acid phosphatase-5b (TRACP-5b) and osteocalcin.

Conclusions

SGLT2 inhibitors may negatively affect bone metabolism by increasing serum PTH, CTX, and decreasing serum ALP. This conclusion needs to be verified by more studies due to the limited number and quality of included studies.

Systematic review registration

PROSPERO, identifier CRD42023410701