bluuebunny/crossref_metadata_2025 huggingface dataset:
La blockchain para transmitir, trazar y certificar valor en el ámbito académico
Authors: Moreno-Ballesteros Ana María
Published: August 2023

La tecnología blockchain es una tecnología disruptiva que permite intercambiar activos digitales entre pares y es considerada como una nueva capa de Internet, aquella dedicada a la transferencia de valor. Esta nueva tecnología descentralizada (es decir, sin un ente de control central, sino que está basada en reglas de consenso ejecutadas por un algoritmo) está llamada a transformar la forma de hacer transacciones, ya que elimina a los intermediarios de confianza tal como los conocemos hasta el momento para empoderar a los usuarios. Esta tecnología ha demostrado ser segura, a través de la adopción de los criptoactivos (uno de los aplicativos de esta tecnología), y abre la posibilidad al desarrollo de múltiples aplicaciones. La blockchain es una herramienta idónea para el desarrollo de la industria digital en su nueva etapa: la de tramitar activos directamente entre usuarios. Desde UxTIC, se ha identificado que el sector de la educación no está exento de ser impactado por esta tecnología.
Rola regulatorów transkrypcji w kontroli ekspresji genów prokariotycznych na przykładzie modelowej bakterii Pseudomonas aeruginosa
Authors: Modrzejewska-Balcerek Magdalena , Bartosik Aneta Agnieszka
Published: August 2023

Bakterie Pseudomonas aeruginosa spotykane są często w środowisku naturalnym jak woda czy gleba, ale zaliczane są także do oportunistycznych patogenów ludzi i zwierząt. Charakteryzuje je duża zdolność do przetrwania w bardzo różnych niszach ekologicznych. Adaptacja i umiejętność dostosowania do zmiennych warunków środowiska wynika z rozbudowanych sieci regulacyjnych tych bakterii i wykorzystania bogatego repertuaru kodowanych w genomie białek, ścieżek metabolicznych, mechanizmów obronnych i adaptacyjnych.

Regulatory transkrypcji są kluczowymi elementami regulacji ekspresji genów, które odpowiadają na sygnały z otoczenia, włączając lub wyłączając określone ścieżki. Kompleksowe badania regulatorów transkrypcji z wykorzystaniem metod transkryptomicznych, genomicznych, regulacyjnych dostarczają wiedzy na temat mechanizmów ich działania, regulowanych genów i procesów, umożliwiając poznanie i zrozumienie skomplikowanych często sieci regulacyjnych zawiadujących przeżyciem komórki w danym środowisku i warunkach.

Celem niniejszej pracy jest przedstawienie kluczowych zagadnień związanych z regulacją transkrypcji bakteryjnej na podstawie przeglądu danych literaturowych oraz zobrazowanych na przykładzie P. aeruginosa i charakterystyki mechanizmów regulacji ekspresji genów zaangażowanych między innymi w wirulencję tej bakterii.
PRIME EDITING - nowa metoda edycji genów
Authors: Blicharska Dalia , Szućko-Kociuba Izabela , Filip Ewa , Orłowska Anna , Skuza Lidia
Published: August 2023

Metoda Prime Editing’u polega na wprowadzeniu oczekiwanych edycji w obrębie danego genomu przy zastosowaniu konstruktu zbudowanego z nikazy Cas9, pegRNA oraz odwrotnej transkryptazy, odpowiedzialnej za syntezę odcinka, który ma następnie zostać włączony do edytowanej nici. Technika ta bazuje na wcześniej odkrytej metodzie CRISPR/Cas9. Różni się od CRISPR/Cas9 brakiem generowania podwójnych pęknięć w obrębie helisy DNA co zawdzięcza swojej złożonej konstrukcji, w tym m.in. obecności dodatkowych elementów tj.: odwrotnej transkryptazy oraz matrycy zawartej w obrębie pegRNA. PE wykorzystuje się do wprowadzania modyfikacji w obrębie podwójnej helisy DNA.

Praca porusza głównie tematykę kreowania i udoskonalania oraz testowania nowoczesnej metody Prime Editing’u. Podano informacje na temat budowy oraz sposobu funkcjonowania systemu, a także opisano dotychczas przeprowadzone badania z zastosowaniem PE, wykonane w obrębie genomów komórek pochodzących z organizmów roślinnych, zwierzęcych oraz ludzkich. W pracy zawarto również informacje dotyczące potencjalnych korzyści oraz nadzieje związane z zastosowaniem tej innowacyjnej metody.
A comparison of neonatal outcomes after taking progesterone pills and progesterone intramuscular injections in preterm labor: An RCT
Authors: Dalili Maryam , Barkhori-Mehni Moeeneh , Karami Robati Fatemeh
Published: August 2023

Background: Approximately two-thirds of infant mortality within the first year of life are caused by preterm labor (PL).
Objective: This study aimed to investigate the effects of progesterone-based compounds to prevent PL.
Materials and Methods: This randomized clinical trial study was conducted on 146 pregnant women admitted to Department of Obstetrics and Gynecology, Afzalipour hospital in Kerman University of Medical Sciences, Iran in June 2019. The participants with PL received Tocolytic and 12 mg Betamethasone in 2 doses over 2 days to mature the fetus’s lungs. Stopping PL was considered a 12-hr period without any contractions after finishing the Tocolytic. Following the successful cessation of PL, the participants were monitored for 48 hr. Subsequently, the participants were divided into 2 groups. Participants received 200 mg Lutogel capsules orally per day in group A while group B received a weekly dose of 250 mg Proluton in the form of intramuscular injection, respectively. Treatment in groups continued until the 36th wk of delivery. The participants were followed-up weekly, and if any signs of PL were detected, an obstetrician carried out a vaginal examination.
Results: The incidence of PL was the same in both groups. There was no significant difference in the latent phase, average birth weight, and the neonatal intensive care unit admission frequency (p = 0.07, 0.17, 0.58, respectively) between groups.
Conclusion: No difference in the results obtained from the neonatal outcomes evaluated in groups. Both medications similarly led to recovering pregnancy and neonatal outcomes caused by PL. Applying the oral form with similar beneficial effects were pointed out in this study, which can be a solution to the issues caused by numerous injections that are inevitable in the injected administration of this medicine.
Key words: Obstetric labor, Premature, Progesterone, Oral, Injections.
A treatment approach of severe vulvar edema in ovarian hyperstimulation syndrome patient: A case report
Authors: Sadeghi Leila , Ghasemzadeh Aliyeh , Hamdi Kobra , Navali Nazli , Hakimi Parvin , Farzadi Laya
Published: August 2023

Background: Ovarian hyperstimulation syndrome (OHSS) is a serious life-threatening complication of infertility treatment. Vulvar edema is a disease with various causes and frequent phenomena seen in physiological and pathologic conditions like pregnancy, inflammatory disorders, tumors, idiopathic reasons, and most importantly, in the severe form of OHSS.
Case Presentation: Here, we report a 26-yr-old woman with severe OHSS, recombinant follicle-stimulating hormone therapy. 8 days later, we observed a mild and asymmetrical swelling of the vulva with severe edema in the right labia. Due to the worsening of the vulvar edema even after 15 days of conservative treatment, hand massage and compressive bandaging of the vulva were performed, which caused rapid recovery within 20 min of the case.
Conclusion: Treatment with a hand massage with lubricant gel followed by compressive bandaging resolved the vulvar edema immediately; it is an easy procedure without any adverse events.
Key words: Ovarian hyperstimulation syndrome, Massage, Vulva.
New Insights into Pathogenesis, Diagnosis and Treatment of Psoriatic Arthritis
Authors: Dadgar Farhad , Rostamian Abdolrahman , Najafizadeh Seyed Reza , Movaseghi Shafieh , Saffarian Zahra
Published: August 2023

Introduction: Psoriatic Arthritis (PSA) is an inflammatory musculoskeletal disorder characterized by significant dysfunction in synovial tissue, tendons and axial sites. PSA is associated with metabolic comorbidities such as diabetes, obesity, congestive heart failure, fatty liver disease, depression and/or anxiety. Due to differences in the clinical manifestations of PSA, some patients are not diagnosed through clinical examination. Delayed psoriatic arthritis diagnosis or consultation has been related to low quality of life and increased frequency of comorbidities and persistent inflammatory state. The aim of the present study was to explore multiple etiologies of PSA, screening tools, and pharmaceutical therapy. Articles were searched from international databases including Magiran, Scopus, Google Scholar, PubMed, and Springer. The keywords of Psoriatic Arthritis, Screening tools, pathogenesis, treatment, and Biomarkers were used to extract articles.
Conclusion: Our study showed that heterogeneity in the etiology of PSA was a major reason for classification problems within this disease spectrum. The explanation for this disease heterogeneity may be focused on variations in genetic and environmental factors. Screening strategies (ex: CASPAR criteria and biomarkers) are a significant first step in early treatment. Moreover, many types of therapy are available to help decreased joint problems, muscle weakness, and disease severity. Detection of dependent factors related to PSA might help in the early intervention of these patients to address clinical and para-clinical issues.
Here we have provided an updated review of the early diagnosis, clinical features, pathogenesis, screening tools, biomarkers, and treatment recommendations, such as new biologic medications, for Psoriatic Arthritis.
Evaluate the Effect of Dendrosomal Curcumin on Expression Level of HOTAIR Long Noncoding RNA in MCF-7 Breast Cancer Cell Line
Authors: Mehrabi Maryam , Alemohammad Sara , Dashtebozorgi Reza , Tahmasebi Birgani Maryam , Hajjari Mohammad Reza , Mohammadi-Asl Javad
Published: August 2023

Introduction: Breast cancer is one of the most common malignancies in women. Treatment with herbal drugs has been considered by researchers due to the lower side effects. Curcumin is a polyphenol extracted from turmeric with confirmed anti-cancer properties. Curcumin is water-insoluble with rapid metabolism. Drug delivery using nano-carriers is suggested to overcome such limitations. The aim of this study was based on evaluating the effect of Dendrosomes curcumin on expression level of HOTAIR long noncoding RNA in MCF-7 breast cancer cell line.
Methods: This study was an applied basic research. Firstly, curcumin was loaded in dendrosomes and the entry of dendrosomal curcumin into cells was studied using fluorescent microscopy.  Cell death was investigated using MTT assay and apoptosis detection kit. The expression of HOTAIR gene was measured using real-time PCR. Increased expression of this gene was reported in a wide range of tumors. The data were analyzed using GraphPad Prism V9.5 statistical software, using NOVA one-way statistical analysis and Student t-test; the results were reported as mean ± standard deviation.
Results: Dendrosomes increased the solubility of curcumin. The effective inhibitory doses of dendrosomal curcumin after 24 and 48h treatment were 25 and 20 micromolar, respectively. The percent of cells undergoing early apoptosis were 22.97±0.03 and 56.22±0.05, respectively, which was statistically significant in comparison with non-treated control cells. Following 24 and 48h treatment with 20 micromolar of dendrosomal curcumin, the HOTAIR gene expression was significantly decreased (P=0.001).
Conclusion: These findings suggest that dendrosomal curcumin may promote breast tumor cells toward programmed cell death by reducing HOTAIR gene expression.
Factors Related to Reduced Bone Density in β-Thalassemia Major Patients: Mazandaran Thalassemia Registry
Authors: Karami Hossein , Kosaryan Mehrnoush , Naderisorki Mohammad , Esfandiari Fatemeh , Ghazaiean Mobin , Aliasgharian Aily , Fallah Hanie , Shakeri Salameh , Darvishi-Khezri Hadi
Published: August 2023

Introduction: OsteoPenia and osteoPorosis are known to be one of the main comPlications of β-thalassemia major (β-TM). The aim of this study was to determine the factors associated with decreased bone density of these Patients.
Methods: Lumbar and femoral neck bone mineral density (BMD) in β-TM Patients characterized via Dual-energy X-ray absorPtiometry (DXA) to PinPoint the association of iron chelators, diabetes mellitus, serum ferritin above 3000 ng/mL, hemoglobin below 8 gr/dl, using hydroxyurea, liver siderosis and moderate to severe hePatic and cardiac siderosis with BMD. The information was collected from the thalassemia registry in 2019 and statistical analysis was Performed by STATA-13 software.
Results: Out of 1959 ParticiPants with β-thalassemia major registered in the registry, 139 ones (7.09%) had bone mineral density (53 males and 86 females). The Prevalence of abnormal bone density in the lumbar and femoral neck was (52.48 to 47.66) 57.5 and (40.18 to 57.52) 48.85 Percent, resPectively. After adjusting for the effects of Possible interventions, the odds ratio of abnormal bone density in the Patients consuming hydroxyurea and deferasirox were 0.24 (0.03 to 1.73) and 0.25 (0.03 to 1.69), resPectively. The highest odds were 8.21 (0.18 to 360.22), and 6.72 (0.60 to 74.83) for moderate to severe cardiac and hePatic dePosition, resPectively.
Conclusion: The Prevalence of osteoPenia and osteoPorosis is high among thalassemia major Patients. ConsumPtion of hydroxyurea and deferasirox is the most imPortant Protective factor and moderate to severe cardiac and hePatic siderosis are the most imPortant risk factors for abnormal bone density.
Role of Positive Adolescent Development and Self-compassion in the Aggression Tendency of Female High School Students in Yazd City
Authors: Fotoohi Fatemeh , Barzegar Bafroei Kazem , Hassani Hossain
Published: August 2023

Introduction: The present study was conducted with the aim of investigating the role of positive adolescent development and self-compassion in the aggression tendency of female students of high schools in Yazd City.
Methods: The research design in this study was descriptive and correlational. The participants in this research were 362 female students in the second grade of high school in Yazd City in the academic year of 2020-2021, who were selected based on random cluster sampling In order to collect data, Goldhoff et al.'s Positive Development Questionnaire (2014), Self-Compassion Questionnaire (2003) and Bass and Perry's Aggression Questionnaire (1992) were used. Data analysis and correlation method based on the approach Structural equation modeling was done using AMOS software, version 21.
Results: The results showed that the positive transformation of adolescence has a direct, positive and significant effect on self-compassion (β = 0.66 and P < 0.01) and a direct, negative and significant effect on aggression (β = -0.33 and P < 0.01) and self-compassion have a direct, negative and significant effect on aggression (β = -0.29 and P < 0.01) in the female students of the second grade of high school in Yazd City.
Conclusion: self-compassion plays a mediating role in the relationship between the positive development of adolescence and aggression of female students in the second grade of high school in Yazd City and by increasing the positive development of adolescence and self-compassion in adolescents, their tendency to aggression can be reduced.
Epidemiological Study of Adult Patients with Acute Abdomen Referred to Fatemi Ardabil Hospital from 2020 to 2021
Authors: Arabzadeh Amir Ahmad , Amini Keyvan , Sharghi Afshan , Ataei Mahsa , Seyed Sadeghi Mirsalim
Published: August 2023

Introduction: The prevalence and causes of acute abdomen can be different in various regions and races. Knowing the epidemiology of the disease can prevent unnecessary surgeries and unwanted complications caused by surgery. The present study was conducted with the aim of epidemiological investigation of adult patients with acute abdomen referred to Fatemi Ardabil Hospital from 2020 to 2021.
Methods: A cross-sectional descriptive study was conducted during a year with a statistical population of 1031 patients referred to the Emergency Department of Fatemi Ardabil Hospital with abdominal pain. The sampling method was easy non-probability sampling. The information of these patients was collected through a preliminary questionnaire and analyzed using SPSS 16 software.
Results: In this study, the number of 535 participants were male and 496 were female. 53.5% of patients had non-bilious vomiting، 67.6% had normal abdominal function، 53% had anorexia، 16.2% had abdominal distension and 14.3% had fever. 20.1% had pain in the right lower quadrant، 16.1% no tenderness، 15.6% rebound tenderness، 5.4% guarding، 5.8% psoas sign and 16.3% Murphy sign. 27% of abdominal pain was related to appendicitis، 20% to cholecystitis، 15.3% to intestinal obstruction and the lowest number of cases were related to metastasis and ectopic pregnancy with 0.3%.
Conclusion: The best tools available for examining and managing abdominal pain are clinical examination and a comprehensive history.
A relação cultura e natureza e a diversidade dos agroecossitemas camponeses: uma percepção estético-visual
Authors: Guimarães Clara Soares de Freitas , Mendonça Maria Alice Fernandes Corrêa , Cardoso Irene Maria
Published: August 2023

Este artigo aborda a relação cultura/natureza a partir da manifestação do cultivo e da conservação de sementes crioulas na mesorregião da Zona da Mata, em Minas Gerais. O trabalho é resultante de uma pesquisa qualitativa realizada com agricultores(as) familiares camponeses(as) inseridos(as) na rede de agroecologia local. Para tanto, ancoramo-nos em três instrumentos de coleta de dados como estratégia metodológica. São eles: pesquisa documental, entrevistas semiestruturadas e análise estético-visual das fotografias e dos vídeos enviados pelos(as) entrevistados(as). Verificou-se que as sementes crioulas são fruto dos significados-usos e da percepção estética de agricultores(as) em relação ao agroecossistema no qual estão inseridos(as). As sementes crioulas diversificam as paisagens e simbolizam a resistência ontológica da agricultura familiar camponesa. A sua diversidade e a memória biocultural a elas associada são fundamentais no manejo agroecológico dos agroecossistemas. A memória biocultural desses(as) agricultores(as) expressa conhecimentos reveladores de outras formas de se relacionar com os ecossistemas e de viver e habitar o território, evidenciando cosmologias, que não correspondem às perspectivas dominantes de desenvolvimento definidas pela sociedade moderna capitalista.
Produção de cimentos de baixo impacto ambiental: perspectivas para a região amazônica
Authors: Braga Nállyton Tiago De Sales , Arruda Junior Euler Santos , Barata Márcio Santos
Published: August 2023

A produção de cimentos com menor pegada ecológica é de extrema relevância como medida mitigadora da emissão de gases poluentes pela indústria de construção civil. Desse modo, este estudo tem como objetivo discutir o uso de argila caulinítica e calcário, matérias-primas amplamente disponíveis na região amazônica, e que apresentam alto potencial para produção de cimentos de elevado desempenho, menor consumo energético e baixa emissão de gás carbônico. Além dos parâmetros operacionais que devem ser levados em consideração para a produção e comercialização de cimentos de baixo carbono, como as particularidades dos insumos da região, o impacto sobre a indústria e as questões ambientais envolvidas na extração de tais matérias-primas, há o desafio de produzir em coerência com as demandas do mercado consumidor, em especial o segmento informal ou de autoconstrução, que responde por aproximadamente 40% de todo o cimento consumido no planeta, e para quem cimentos de elevado desempenho não apresentam interesse econômico.
Conhecimento tradicional dos pescadores artesanais sobre a bioecologia do pirarucu (Arapaima spp.) na microrregião do Tapará, Santarém-Pará-Brasil
Authors: Lemos Tatiane Almeida , Porto Braga Tony Marcos , Lima da Silva Alanna Do Socorro
Published: August 2023

Diante da importância do Pirarucu (Arapaima spp.) para as comunidades ribeirinhas da Amazônia, o objetivo deste estudo é o de analisar o conhecimento biológico sobre a espécie em áreas com e sem manejo pesqueiro, e como esse conhecimento influencia na captura da espécie na região. As informações foram coletadas por intermédio de formulários semiestruturados. As comunidades foram dispostas em dois grupos: a) comunidades que têm manejo do pirarucu (CCMP): Santa Maria e Tapará-miri; e b) comunidades que não têm manejo do pirarucu (CSMP): Barreira e Correio do Tapará. Os dados foram analisados por intermédio de estatística descritiva e cognição comparada.  O estudo demonstrou que os pescadores artesanais, nas duas categorias de comunidades analisadas, apresentam vasto conhecimento sobre a ecologia do pirarucu e este, está em conformidade com a literatura cientifica.
A metropolização do espaço no Amapá: por uma abordagem socioespacial da região metropolitana de Macapá
Authors: Santos Romário Valente , Brito Amaral Márcio Douglas
Published: August 2023

Macapá e Santana são as principais cidades da Amazônia Setentrional sob influência da Metrópole de Belém. Juntas exercem centralidade sobre o estado do Amapá, o Golfão Marajoara e a porção paraense do Vale do Jari ao sul amapaense. Compreender as dinâmicas espaciais desse conjunto espacial é essencial para a avaliação crítica das políticas de desenvolvimento, especialmente do ponto de vista da urbanização, pensadas e executadas no Aglomerado Urbano Macapá-Santana. O presente artigo tem como objetivo principal analisar criticamente a institucionalização da produção do espaço no Amapá especialmente sobre a criação de uma região metropolitana, a Região Metropolitana de Macapá, em cidades consideradas por alguns autores como cidades médias. A análise considera o debate teórico e institucional sobre regiões metropolitanas e aglomerados urbanos, elementos essenciais para se pensar as políticas de desenvolvimento urbano adequadas à realidade local. A revisão bibliográfica e a análise documental foram os procedimentos metodológicos básicos adotados.
Plano de gestão de logística sustentável para uma instituição de ensino superior: um plano de ações
Authors: Cordeiro Marcus Vinicius Cruz , Nadae Jeniffer De , Nascimento Diego Coelho do , Moura-Fé Marcelo Martins de , Ramos Ingrid Mazza Matos
Published: August 2023

O trabalho analisa a viabilidade de um plano de ações destinado à implantação de um Plano de Gestão de Logística Sustentável para uma Instituição de Ensino Superior, localizada na cidade de Juazeiro do Norte-CE. Instituições de Ensino Superior, além da produção de conhecimento, podem servir como exemplos para a sociedade, na adoção de práticas de sustentabilidade, cumprindo o normativo legal e também sua função social. Para tanto, foi realizado um diagnóstico da situação atual da instituição, por meio de pesquisa exploratória, bibliográfica e estudo de caso, visando a verificação de práticas e ações já utilizadas pela instituição e observando-se as condições favoráveis à implementação da proposta aventada,  a qual foi elaborada com a ferramenta 5W2H, através de 07 (sete) ações-chave, culminando com a implementação de um PLS sólido e eficaz a ser adotado pelo órgão público abordado.
Levantamento dos métodos de elaboração de corredores ecológicos utilizando SIG: uma revisão bibliográfica sistemática
Authors: Oliveira Renan Angrizani de , Galvão Jonilson Michel Fontes , Simonetti Vanessa Cezar , Martins Antonio Cesar Germano , Silva Darllan Collins da Cunha e
Published: August 2023

A expansão urbana vem ocasionando processos de fragmentação florestais. Este fato motiva a necessidade de implementação de corredores ecológicos (CE) para atenuar os impactos ambientais negativos. Visto isto, este estudo conduziu uma revisão bibliográfica sistemática sobre pesquisas que propõe a elaboração de CE, buscando identificar o Sistema de Informação Geográfica (SIG) e as principais extensões utilizadas para a proposição do CE, além de apontar o país, a espécie alvo, e ano das publicações destas pesquisas. A revisão foi realizada para os estudos de 2009 a 2021, utilizando-se as bases de dados: ScienceDirect, Scopus, Springer Link e Web of Science. No total, foram selecionados 530 artigos, dos quais após a sistemática de exclusão, restaram 39. O SIG mais utilizado foi o ArcGIS, e o país que apresentou o maior número de estudos foi a China. Dentre os modelos utilizados, se destacou o caminho de menor custo. Também verificou-se carência de estudos sobre a utilização de SIG para proposição de CE, além de ser possível constatar que alguns dos projetos estudados não apresentaram todos os elementos necessários, inviabilizando a sua reprodutibilidade.
Crise dos processos civilizatórios, Amazônia e universidade
Authors: Aveiro Martín
Published: August 2023

Nós propomos repensar o projeto universitário de Darcy Ribeiro no momento atual de crise dos processos civilizatórios e do retorno da rota transamazônica, começada pela ditadura brasileira, entre os anos sessenta e setenta, cujo lema era: “uma terra sem homens para homens sem-terra”. Nesse sentido, precisamos revisar a concepção dos sujeitos intervenientes e, ao mesmo tempo, compreender as fissuras da modernidade, dos processos civilizatórios que transformaram a Amazônia até a atual revolução 4.0, como nova modalidade de capitalismo desumanizador e excludente. Pois bem, aos danos ambientais, causados pela depredação dos recursos naturais, junta-se à ausência de um modelo universitário que dê respostas às urgentes necessidades sociais naquela região do planeta, de uma imensa riqueza natural e, ao mesmo tempo, das maiores desigualdades do Brasil. Por isso, a partir de uma releitura interpretativa dos textos do intelectual, que realizou suas primeiras tarefas como antropólogo junto aos indígenas amazônicos, Nós nos fazemos a pergunta que ele mesmo fez: universidade, para quê?
Vida quilombola na comunidade de Itacuruçá, Pará
Authors: Nascimento Monique Teresa Amoras , Carvalho Jéssica Fernanda Carvalho de , Silva Brenda Caroline Martins da , Farias Iago Sérgio de Castro , Castro Nádile Juliane Costa de
Published: August 2023

O artigo objetiva descrever as relações entre saúde e processos históricos em uma comunidade quilombola da Região Norte do Brasil. Metodologicamente, mobilizou-se o estudo etnográfico, com uso do diário de campo e do método observacional. A coleta foi realizada entre julho de 2021 e fevereiro de 2022, a partir de três visitas in loco à comunidade quilombola de Itacuruçá, pertencente à zona rural do município de Abaetetuba (PA). Os resultados foram analisados, a partir dos pressupostos da Determinação Social da Saúde, com emprego da análise de conteúdo. Dessa maneira, identificou-se os seguintes elementos na análise temática: ambiência e acessibilidade; cultura e modo de vida; e redes sociais e de saúde. Conclui-se que o modo de vida, os processos históricos e as dinâmicas do modelo econômico hegemônico são observados no contexto da comunidade, possuindo intervenções pontuais e limitadas em saúde, em virtude do isolamento geográfico e do acesso restrito a serviços dessa natureza.
A importância do ICMS ecológico para os municípios de Mato Grosso
Authors: Spanholi Maira Luiza , Young Carlos Eduardo Frickmann , Videira João Augusto Muniz
Published: August 2023

O ICMS Ecológico é um esquema de repasse de recursos fiscais para municípios por critérios ambientais atribuídos por legislação estadual. O objetivo do trabalho é verificar o impacto do ICMS Ecológico nas receitas e índices de bem-estar dos municípios de Mato Grosso. Como metodologia foi utilizada analise descritiva, regressão linear múltipla e análise em dados de painel. O ICMS Ecológico é importante para a receita de muitos municípios do estado, representando mais de 50% do total da receita de ICMS que alguns municípios recebem. Embora tenha limitações, incentiva os municípios a aumentarem seus gastos com a função Gestão Ambiental, e resulta em aumento, em média, de R$ 0,15 em gasto ambiental para cada R$1,00 repassado em forma de ICMS ecológico aos municípios. Os dados em painel demonstraram que as receitas obtidas através do ICMS Ecológico podem ter influência nos índices de desenvolvimento municipal (IFDM Saúde, IFDM Educação e IFDM Emprego e Renda). Conclui-se que, embora possa ser aprimorado, o ICMS Ecológico no Mato Grosso tem sido importante para estimular a preservação ambiental, aumentar a área protegida, reforçar a capacidade financeira dos municípios beneficiados e incentivar o investimento na gestão ambiental.
Impactos ambientais das fibras de algodão e poliéster na indústria da moda
Authors: Do Bem Natani Aparecida , Linke Paula Piva
Published: August 2023

Este artigo apresenta uma discussão acerca da relação moda e meio ambiente, partindo das concepções de ultra fashion, fast fashion e slow fashion, considerando os impactos causados pelo setor da moda, apresentando dados referentes ao descarte de peças pós-consumo e fazendo um comparativo entre as fibras de algodão e poliéster e o impacto ambiental de ambas. Considerando as limitações do meio ambiente e as formas de produção e consumo, assim como os processos e materiais utilizados dentro do setor têxtil há que se promover uma mudança intensa na forma de consumo e descarte dos produtos.
Biosynthetic Gold Nanoparticles as Sensitive and Selective Colorimetric Method for Mercury Ions
Authors: ABDULGHAFOR AHMED Maryam , AHMED FARHAN Safana , MONİEM DADOOSH Rasha , MOHAMMED NOORİ JASSİM Abdulkadir
Published: August 2023

Gold nanoparticles (AuNPs) are widely studied materials that have intense applications in various fields. Different methods use to synthesize the AuNPs, one of them is eco-friendly biological method, known as "green synthesis" a simple and inexpensive method. The Synthesis of AuNPs, using ginger extract is described here. The components found in ginger work as a stabilizing and reducing agent. Hydrogen tetrachloroaurate (HAuCl4) are mixed with the ginger extract to produce AuNPs. The Surface Plasmon Resonance (SPR) measured at λmax = 540 nm. UV-Vis, FTIR and Zeta potential are used to identify AuNPs, as well as AFM and SEM. Data indicate that AuNPs has a spherical structure. The results demonstrate that AuNPs stabilized by ascorbic acid were used as a colorimetric probe for Hg2+ ions, based on the production of (Au-Hg) amalgamate which made changes in their absorbance, due to its ability to reduce Hg2+ to Hg0, to enhance amalgamation. Practically, this procedure has successfully worked to detect Hg2+ in tap water as a sensitive and selective probe with upper limit of detection equal to 120 µM as well as the limit of detection (LOD) equal to 0.65 µM, so the method proved to be sensitive and selective probe.
Sınıf Öğretmenlerinin Çevre Okuryazarlık Düzeylerinin Farklı Değişkenlere Göre İncelenmesi
Authors: GÜNEY Esin , AKILLI Mustafa
Published: August 2023

Bu araştırmada sınıf öğretmenlerinin çevre okuryazarlık düzeylerinin farklı değişkenlere göre incelenmesi amaçlanmıştır. Bu bağlamda çevre okuryazarlık alt boyutlarından bilgi, tutum, davranış ve duyuşsal eğilim; cinsiyet, mesleki kıdem, görev yapılan okul tipi, görev yapılan yerleşim yeri ve mezun olunan fakülte değişkenlerine göre incelenmiştir. Çalışmada deneysel olmayan karşılaştırmalı model kullanılmıştır. Araştırmanın örneklemini Şanlıurfa ilinde Milli Eğitim Bakanlığına bağlı kurumlarda görev yapmakta olan 579 sınıf öğretmeni oluşturmuştur. Verileri toplamak amacıyla çevre bilgi testi, çevre davranış ölçeği, çevreye yönelik duyuşsal eğilimler ölçeği ve çevre sorunlarına yönelik tutum ölçeği kullanılmıştır. Araştırmada kullanılan ölçeklerden elde edilen veriler SPSS paket programı kullanılarak çözümlenmiştir. Analiz sonucunda normal dağılım göstermediği durumlarda, cinsiyet ile ilgili yapılan analizlerde Mann-Whitney U testi, diğer değişkenler için de Kruskal Wallis testleri kullanılmıştır. Elde edilen verilerin normal ya da normale yakın dağılım gösterdiği durumlarda ise cinsiyetin herhangi bir etkiye sahip olup olmadığının belirlenmesinde bağımsız gruplar t-testi, diğer değişkenlerin herhangi bir etkisinin bulunup bulunmadığıyla ilgili de tek yönlü varyans analizi (One Way ANOVA) uygulanmıştır. Cinsiyet, mesleki kıdem ve görev yapılan okul tipine göre bilgi ve duyuşsal eğilim alt boyutlarında anlamlı farklılık varken tutum ve davranış alt boyutları için anlamlı farklılık bulunamamıştır. Görev yapılan yerleşim yerine göre bilgi ve davranış alt boyutlarında anlamlı farklılık tespit edilmiş fakat tutum ve duyuşsal eğilim için anlamlı fark bulunamamıştır. Mezun olunan fakülte değişkeni için hiçbir alt boyutta anlamlı farklılık tespit edilmemiştir.
Policy Environment Analysis in Indian Fertiliser Industry
Authors: Sharma Seema
Published: August 2023

The objective of this paper is to analyse the impact of Government policy decisions in fertiliser industry.Â  Indian Government has taken two strategic decisions in this industry viz., introduction of Retention Price Scheme in 1976 and the decontrol of phosphatic and potassic fertilisers in 1992. The two tier pricing implemented in the first decision has made a positive impact on the growth of this industry and the agricultural production.Â  However the second decision to partially decontrol the phosphatic and potassic fertilisers and keep urea under control has led to a lopsided environment in this industry. This growing distortion in the nitrogenpous, phosphatic and potassic (NPK) usage in Indian agriculture is a threat to agricultural productivity growth. Therefore, there is a need to come out with sustainable policy which will not only improve the NPK balance in the economy but also improve the health of Indian fertiliser industry by ensuring profits to the producers. The fertilizer industry need tom be in line with rest of the economy hence a phased decontrol is thus considered is desirable so that the farmers interests can be protected.
Investigation of Effective Factors on the Process of Corporate Entrepreneurship in Iran
Authors: Mokhtari Mehran. Bayekolaei
Published: August 2023

The study of human life from the beginning of the history of creation to the present suggests that the Entrepreneurial factor plays an important role in the development of societies. In other words, we can say that Entrepreneurship and Entrepreneurs have been active since old times, but they have been considered as proper factors until recently. Entrepreneurship, creativity and venturing are considered as the fuel to the engine of modern economy. Entrepreneurs are on the top of the business, they are looking for opportunities, and creativity is also deemed to be as the key to their success. Entrepreneurs considers change as a natural phenomenon, they are always looking for it show reaction to it and make use it as an opportunity. The in creasing complexity and competition in today's world which is accompanied by the rapid developments of passing and international environment from industrial society to informational society also changing the national economy in to the global led to the consideration of Entrepreneurship as the drive motor to the development of economy.
Estimation of Import and Export demand Functions Using Bilateral Trade Data ___ the case of Pakistan
Authors: Haider Jahanzaib , Afzal Muhammad , Riaz Farah
Published: August 2023

We estimated the import and export elasticities of Pakistan trade with traditional trade partners and some Asian countries to see the dynamics of Pakistan trade from 1973 to 2008. OLS results suggest that income is the principal determinant of exports and imports. Pakistan exports are cointegrated with Japan and USA while the imports are cointegrated with UAE and USA. Pakistan imports and exports are cointegrated with Bangladesh and Sri Lanka but not with India and China. Income and exchange rate are both important determinants of foreign trade. Continuing its trade with traditional partners and making efforts for greater market access to USA and EU, Pakistan should make efforts to increase its trade with Asian countries notably China and India because both are fast growing economies and have huge market.
Increase of safety of palletized-piece cargo delivery: moment of risk and ways to decrease cargo loss risk at delivery
Authors:   Saint Petersburg Mining University (SPMU), Matveev Alexander Grigoryevich , Menukhova Tatyana Anatolyevna ,   Saint Petersburg Mining University (SPMU)
Published: August 2023

The paper analyses an operation of a transportation company warehouse and suggests ways to calculate requirements of company in master containers with the consideration for seasonal fluctuations of demand, various volumes of cargo and presence of side residue of cargo, which require minimum costs.
Processes of commutation of rectifier currents of a semi-conductor booster
Authors:   Ural state university of railway transport (USURT), Shtin Andrey Nikolaevich , Shumakov Konstantin Gennadyevich ,   Ural state university of railway transport (USURT), Lesnikov Dmitriy Valentinovich ,   Ural state university of railway transport (USURT), Frolov Leonid Alexandrovich ,   Ural state university of railway transport (USURT)
Published: August 2023

One of the main tasks of a railway power supply system is the provision of increased traffic volumes especially on direct current railway sections. For this reason the personnel of traction substations uses various means and methods of power supply strengthening including boosters representing two parallel thyristor bridges shunted by diodes. The paper considers three processes of commutation of rectifier currents arising in boosters: between two thyristors, between a shunt diode and thyristors and between thyristors and a shunt diode. The paper presents a detailed mathematical description of these processes. As a result, the authors gained a general formula for calculation of all three angles of commutation, with the use of which the authors have carried out all calculations. Reliability of gained expressions is confirmed on a physical model.
Assessment of influence of contact wire sag on possibility of increase of driving speed on the Ekaterinburg — Chelyabinsk catenary section
Authors:   Ural state university of railway transport (USURT), Kovalev Alexey Anatolyevich , Andryukov Alexander Vladimirovich ,   Ural state university of railway transport (USURT)
Published: August 2023

The paper presents results of comparison of mechanical calculation of the Ekaterinburg - Chelyabinsk tension catenary section for three compensated catenary suspensions. The authors have calculated catenary wire sags and created wire lists and diagrams for each climatic region for the Ekaterinburg - Chelyabinsk line, which will allow making correct conclusions on increase of driving speed on this section.
Functional architecture of digital model of maintenance and repair of freight cars
Authors:   Ural state university of railway transport (USURT), Sirina Nina Fridrikhovna , Kolodin Alexander Evgenyevich ,   JSC «RZD»
Published: August 2023

Introduction of complex digitalization of car services is determined by progressive development of railway transport. Dynamically developing software products form inseparable requirements to transformation of the industry and dictate inevitable changes in the production architecture. Digitalization of production processes and their internal connections integrates more deeply into technology of maintenance and repair of rolling stock and becomes a basic principle of a production cycle of any level. For forecasting a technical condition of freight cars the authors suggest a model of a system for their phased maintenance and repair. A simulation created in the digital form describes the model that allows repeatedly calculating various production scripts at various given conditions and giving an optimal forecast of final indicators of maintenance and repair of a car without resorting to natural assessment of the result.
Model of realization of barrier functions for provision of safety of freight car fleet at car allowance on the JSC «RZD» infrastructure
Authors:   Ural state university of railway transport (USURT), Sirina Nina Fridrikhovna , Kolodin Alexander Evgenyevich ,   JSC «RZD», Sverdlov Vadim Borisovich ,   JSC «RZD»
Published: August 2023

The paper presents analysis of main reasons of car damage on non-public railway tracks. It shows that the introduction of barrier functions that block the release of cars with unusable parts on the JSC «RZD» infrastructure allows decreasing car damage from failure of cast parts of bogies. The authors give a definition to a barrier function as a blocking reaction of an information system on discrepancy of rolling stock parameters to established requirements. At car allowance on the JSC «RZD» infrastructure after loading-unloading operations they suggest to introduce the barrier function «creating of logical prohibition on car reception from non-public tracks when a damaged car is revealed». The authors have created a simulation model of car allowance on the infrastructure that allow automating allowance procedure and significantly decreasing risks of release of damaged cars. For the development of the mathematical model they propose to use the method of statistical modeling (the Monte-Carlo technique).
Features of calculation of railway track on sleeperless base
Authors:   Emperor Alexander I St. Petersburg State Transport University (PSTU), Dudkin Evgeniy Pavlovich , Kornilov Sergey Nikolaevich ,   Nosov Magnitogorsk State Technical University (NMSTU), Malakhov Maxim Vyacheslavovich ,   Emperor Alexander I St. Petersburg State Transport University (PSTU), Sultanov Nariman Nadimbekovich ,   Emperor Alexander I St. Petersburg State Transport University (PSTU)
Published: August 2023

The paper proposes a method for calculation of strength and settlement of a sleeperless construction that considers a maximum number of factors that affect reliability and safety of a railway track.
Theoretical issues of the organization of transportation using unmanned vehicles
Authors:   Far Eastern State Transport University (FESTU), Vasilyeva Natalia N. , Korol Roman G. ,   Far Eastern State Transport University (FESTU)
Published: August 2023

The article discusses the theoretical provisions in the field of functioning of unmanned vehicles, their classification is given. The implementation of projects to create unmanned vehicles and programs to put them into operation will reduce the expenditure part at the production stage, as well as increase the efficiency of cargo transportation by reducing the time and cost of delivery.
Current trends in the development of supply chains
Authors:   Ural state university of railway transport (USURT), Uzhegova Anna M. , Ponomareva Natalia V. ,   Ural state university of railway transport (USURT)
Published: August 2023

The article provides an overview of the main directions of supply chain development, emphasizes the importance of solving the primary challenges in the field of logistics. The focus is made on the need for digital transformation, the use of advanced technologies and introduction of sustainable practices in the logistics industry to solve the problematic issues and increase the sustainability of supply chains.
Two essences of transport in integrated logistics
Authors:   Scientific Center for Complex Transport Problems of the Ministry of Transport of the Russian Federation, Chebotaev Alik A. , Ivakhnenko Andrey M. ,   Moscow Automobile and Road State Technical University (MADI), Chebotaev Dmitry A. ,   ICT Logistics, Tung Nguyen ,   Moscow Automobile and Road State Technical University (MADI)
Published: August 2023

The article formulates new definitions of logistics as a science and as a means of market and economic activity for public discussion. The issues of creation and functioning of a new complete integrated intra-company logistics chain are considered. The unifying role of transport and its technological and economic essence in logistics are analyzed. Recommendations are given on the calculation of temporary “junctions” in the nodes for multimodal, combined traffic of logistics chains.
The difference of Bishop score change and labor event between oral and vaginal misoprostol in pregnancy beyond 41 weeks
Authors: Maskasoni Maskasoni , Dewantiningrum Julian
Published: August 2023

HIGHLIGHTS

Oral misoprostol is more effective than vaginal misoprostol in cervical ripening as a part of induction of labor.
Oral misoprostol is as safe as vaginal misoprostol.

 
ABSTRACT
Objective: To compare Bishop score changes and labor event between oral and vaginal misoprostol in pregnancy beyond 41 weeks.
Materials and Methods: A total of 52 pregnant women with more than 41 weeks of gestation, had a Bishop score less than 5, and were undergoing induction labor were randomly divided into two groups: oral and vaginal misoprostol. In the oral misoprostol group, participants were given 25 mg of misoprostol in a solution with a concentration of 1 ug/ml every 2 hours. In the vaginal misoprostol group, a 25 mg misoprostol tablet was inserted into the posterior fornix every 6 hours. The two groups were compared in terms of Bishop score during the first 6 hours, changes in Bishop score, labor at term events, neonatal outcomes, complications, and side effects after the administration of misoprostol.
Results: The oral group showed significantly higher changes in Bishop score compared to the vaginal group (5.5 vs 3.6; p=0.0001). The median interval times for induction of labor at term, induction at stage II, and induction at birth were found to be shorter in the oral misoprostol group compared to the vaginal group (7.3 hours vs 10.6 hours, 14.0 hours vs 16.8 hours, and 14.6 hours vs 17.6 hours; p=0.002, 0.003, 0.002). Labor at term occurred much more frequently in the oral group (53.8% vs 15.4%). Additionally, the oral misoprostol group had a 3.5 times higher likelihood of experiencing labor at term within the first 6 hours after the initial administration compared to the vaginal group (OR 3.5, 95% CI 1.33-9.23).
Conclusion: Oral administration of misoprostol for cervical ripening has been demonstrated to be more effective than vaginal administration, greater bishop score changes while maintaining an equivalent level of safety.
A Review on Marburg Virus: Another Zoonotic Pathogen
Authors: Kashyap Priyanka , Ravi Nayak Subham , Verma Gaurav , Sharma Urvashi , Jena Swetapadma
Published: August 2023

Following an outbreak in 1976, virologists in Marburg discovered the Marburg virus. Since 1967, two significant outbreaks of the Marburg virus (MARV) have occurred. They occurred in 1998 and 2004. A MARV infection causes a fatal severe hemorrhagic fever that affects organs and may cause death. Human-to-human transmission and exposure to fruit bats in mines and caves both played a significant part in the expansion of MARV epidemics in African nations. WHO estimates that there is a high probability of national spread and a moderate risk of global dissemination for the epidemic in 2022. Due to the high fatality rate of up to 90%, thorough research into MARV diseases (MVD), which are linked to MARV infection, is essential. Large MARV outbreaks are uncommon, thus clinical examinations frequently fall short of supplying the essential data necessary to decide how to treat the condition. To better understand this harmful virus and the infection it causes, we reviewed and compiled important data on MARV disease outbreaks, pathophysiology, and mode of transmission, Lab diagnosis, symptoms and management strategies in this study.