bluuebunny/crossref_metadata_2025 huggingface dataset:
Impact of urban geology on model simulations of shallow groundwater levels and flow paths
Authors: LaBianca Ane , Mortensen Mette H. , Sandersen Peter , Sonnenborg Torben O. , Jensen Karsten H. , Kidmose Jacob
Published: April 2023

Abstract. This study examines the impact of urban geology and spatial discretization on the simulation of shallow groundwater levels and flow paths at the city scale. The study uses an integrated hydrological model based on the MIKE SHE code that couples surface water and 3D groundwater simulations with a leaky sewer system. The effect of the geological configuration was analyzed by applying three geological models to an otherwise identical hydrological model. The effect of spatial discretization was examined by using two different horizontal discretizations for the hydrological models of 50 and 10 m, respectively. The impact of the geological configuration and spatial discretization was analyzed based on model calibration, simulations of high water levels, and particle tracking. The results show that a representation of the subsurface infrastructure, and near-terrain soil types, in the geological model impacts the simulation of the high water levels when the hydrological model is simulated in a 10 m discretization. This was detectable even though the difference between the geological models only occurs in 7 % of the volume of the geological models. When the hydrological model was run in a 50 m horizontal discretization, the impact of the urban geology on the high water levels was smoothed out. Results from particle tracking show that representing the subsurface infrastructure in the hydrological model changed the particles' flow paths and travel time to sinks in both the 50 and 10 m horizontal discretization of the hydrological model. It caused less recharge to deeper aquifers and increased the percentage of particles flowing to saturated-zone drains and leaky sewer pipes. In conclusion, the results indicate that even though the subsurface infrastructure and fill material only occupy a small fraction of the shallow geology, it affects the simulation of local water levels and substantially alters the flow paths. The comparison of the spatial discretization demonstrates that, to simulate this effect, the spatial discretization needs to be of a scale that represents the local variability in the shallow urban geology.
Brief communication: The northwest Himalaya towns slipping towards potential disaster
Authors: Sundriyal Yaspal , Kumar Vipin , Chauhan Neha , Kaushik Sameeksha , Ranjan Rahul , Punia Mohit Kumar
Published: April 2023

Abstract. The NW Himalaya (India) has been one of the most affected terrains of the Himalaya, subject to frequent disastrous landslides owing to active tectonics and multiple
precipitation sources. This article focuses on two towns (Joshimath and
Bhatwari) of Uttarakhand in the NW Himalaya, which have been
witnessing subsidence for decades. Up until 9 January 2023, Joshimath had
witnessed widespread cracks in more than 500 houses, which has prompted
social unrest in the region. The hillslopes surrounding both towns
comprise highly jointed gneisses with schistose interlayer rock mass. Both towns have subsidences and holes in the road, broken retaining walls, and displaced boulders, and the houses have
cracks in the walls and holes. Recently, such slope instability phenomena have
increased, which is leading to social movements in the region seeking
government action such as possible evacuation and rehabilitation. The present study
used a continuum-modelling-based slope stability simulation to
determine the response of these hillslopes under various loading conditions:
gravity, rainfall, building load, domestic discharge, and seismic load.
Results revealed that the displacement in these hillslopes might reach up to
20–25 m, which will further aggravate the situation. The occurrence of frequent
extreme rainfall in these towns and three major earthquakes, which occurred on 1 September
1803 (Mw 7.8), 20 October 1991 (Mw 6.8), and 29 March 1999 (Mw 6.6), having a hypocentral distance less than 30 km makes such a study more
viable for decision making.
DEL POLICY ANALYSIS A LOS POLICY STUDIES. COMPLEMENTANDO ENFOQUES DE INVESTIGACIÓN EN POLÍTICAS PÚBLICAS PARA LA ATENCIÓN A POBLACIONES MIGRANTES.
Authors: Gutiérrez Landa Cynthia
Published: April 2023

La investigación en políticas públicas tradicionalmente se ha centrado en los análisis orientados a la evaluación de programas gubernamentales, sin embargo, en los últimos años se ha dado una transformación en el campo de estudio que ha llevado a reconocer la política pública como un proceso complejo, así como la necesidad de estudios que contemplen dicha complejidad. Este trabajo tiene busca presentar un marco conceptual que considere ambas visiones al abordar procesos de políticas para la mitigación de problemas públicos, utilizando como ejemplo el caso de la política de atención humanitaria para personas migrantes susceptibles de protección internacional en México.
Contemporary interior space in promoting national identity of traditional Romanian stylistics
Authors: Munteanu Angela
Published: April 2023

Th e traditional Moldovan-Romanian style represents the history traveled through cultural inferences, identity and tradition, with a valuable potential approached in the stylistics of the contemporary rural and urban space. Since ancient times, the Romanian people have built and decorated their home with handmade ornaments, both pieces of furniture and textiles ornamented with symbols transmitted from generation by generation. Today we have a valuable cultural heritage inherited from our ancestors, which is kept with holiness in peasant dwellings, traditional-vernacular architecture in the Moldovan villages. Th e traditional Moldovan-Romanian style is one with an ethnically artisanal rustic aspect, which conveys the idea of nature, through the colors, materials and fabrics used. Th e well-developed craft smanship from the end of the XIX century, the beginning of the twentieth century in Bessarabia puts a great emphasis on the Moldovan-Romanian national style through folk art. Man has always sought to increase the comfort of his homes, today the creators of interiors implement the traditional national stylistics, one with character and connection between health, family and the tradition of the sheavers.
Repeated editions of the tale „Th e little purse with two half-pennies” by Ion Creangă. The evolution of artistic values in Moldovan book graphics in the Soviet and post-Soviet period
Authors: Rocaciuc Victoria
Published: April 2023

Th e tale „Th e little purse with two half-pennies” signed by Ion Creanga appeared in repeated editions in various countries and is one of the best known. Th e analysis and the history of the evolution of the literary subject are of special interest and deserve more extensive research. It is equally curious to compare various plastic approaches to the topics of the tale. In Soviet and post-Soviet Moldova, the book was illustrated by famous graphic artists such as Leonid Grigorașenco, Ilia Bogdesco, Lică Sainciuc, Igor Vieru, Filimon Hămuraru, Andrei Ţurcanu, Anatoli Smîșleaev, Alexei Colîbneac, Simion Zamsa, Elena Karacențev, Sergiu (Serghei) Samsonov and other artists, who have made a remarkable contribution to this fi eld of art. Each book graphic designer has created unique variants of interpreting the illustrated subjects, approaching various artistic techniques and means, compositional and stylistic principles, etc. By studying them, we have the opportunity to compare the creation of these authors. Th us, we have the occasion to meditate on the aesthetic values of current editions compared to previous ones.
Th e compositional role of buildings for spectacle in the urban context
Authors: Trifan Aurelia
Published: April 2023

Public institutions for spectacle are given special attention in detailed urban plans, serving as dominant features and accents in the urban context. Th e importance of buildings of this type requires not only a careful search for the architectural image, taking into account the form of representation, but also the identifi cation of the uniqueness of the object designed to solve urban planning tasks. Aesthetics inspired by buildings for spectacle affi rm and validate their compositional role, cultural and artistic value being described by evaluation criteria such as spatial proportion and structure, visual openings and ability to provide views, expression and style, image and identity, spirit of the time and atmosphere of the place. Th e spectacular side of these buildings becomes evident through the intensifi cation of the formal features: from the treatment of the fronts to the decorative elements.
Effectiveness of Ondansetron with a combination of Curcuma xanthorrhiza and Kleinhovia hospita against Post-Operative Nausea and Vomiting (PONV) after Laparotomy surgery
Authors: Purwoko Purwoko , Adi Permana Septian , Haki Mohandis
Published: April 2023

The study aimed to analyze differences in the effectiveness of ondansetron administration compared to the administration of ondansetron and the combination of Curcuma xanthorriza and Kleinhovia hospita against the incidence of PONV at Dr. Moewardi Hospital. Thirty patients with the physical status of the American Society of Anesthesiologists (ASA) I or II who underwent laparotomy surgery were randomly premedicated by double-blinded method in each group: the control group, namely premedication of 8 mg ondansetron per oral, and the treatment group, namely premedication of capsule combination of ondansetron 8 mg and Curcuma xanthorriza and Kleinhovia hospita 1 gr. PONV was assessed using PONV score assessment. PONV assessment was carried out 2 hours post-operation. PONV scores between the control group and the treatment group was found significant (p = 0.017). There was no significant difference (p > 0.05) in other variables such as age, weight, height, body mass index, and duration of surgery. Risk factors such as gender and smoking history were obtained PONV scores with insignificant differences (consecutive p values = 0.625; 0.527). Premedication of a combination of ondansetron and Curcuma xanthorriza and Kleinhovia hospita in this study proved more effective in reducing PONV scores.
The effect of Mahogany seeds extract (Swietenia mahagoni) on the quantity of macrophages in the Post-tooth extraction wound healing phase of Wistar Rats (Rattus norvegicus)
Authors: Indah Budhy Theresia , Irmawati Anis , Arundina Ira , Sjuhada Oki Aqsa , Condro Surboyo Meircurius Dwi , Ahsania Firyal , Octavianni Raharjo Cecillia , Iqbal Mohammad
Published: April 2023

Tooth extraction often cause tissue damage and wound. After tooth extraction, the wound healing process becomes a major concern because of many complications and makes patients feel the pain suffered. Lande et al. (2015) showed the prevalence of tooth extraction complications, including crown fracture (31.82%), root fracture (13.6%), dry socket (4%), swelling (2.27%), and bleeding (1.6%). Macrophages are a common inflammatory cell in wounds, and the local macrophage population shifts from pro-inflammatory (M1-like phenotypes) to anti-inflammatory (M2-like phenotypes), indicating to the start of the next healing phase. Various alternative materials can help the healing process of wounds, one of which is mahogany seeds. Flavonoids found in Mahagony seeds can influence cell function by boosting the synthesis of PDGF, VEGF, pro-inflammatory cytokines, activating monocytes, and raising the number of macrophages involved in the wound healing. Proving mahogany seed extract (Swietenia mahagoni) affects the number of macrophages in the wound healing process after extracting Wistar rat (Rattus norvegicus) teeth. 20 Wistar rats were divided into four groups there were one control group (K) performed tooth extraction without any treatment, and three treatment groups (P1, P2, P3) performed tooth extraction and topically induced with three different doses of mahogany seeds extract (50 mg/200g rbw, 100mg/200g rbw, 200mg/200g rbw) in the post-extraction socket. Wistar rats were sacrificed on the 3rd day. Observations were made by reading histologic preparations using Hematoksilin Eosin (HE) 400x light microscope magnification. The quantity of macrophages in each group differed significantly between 4 groups (p = 0.003), namely between K1 and P1 (p = 0.008), P1 and P3 (p = 0.001), P2 and P3 (p = 0.006). Mahogany seeds extract affects the wound healing process, with 50mg/200g rbw as the optimal dose
In-silico Studies of Active Phytochemicals from Siddha Medicinal Herbs of Karisalai Chooranam against SARS-CoV-2 main Protease (3CLpro), RNA Dependent RNA Polymerase and Angiotensin-Converting Enzyme II Receptor
Authors: A Mariappan. , J Thanalakshmi. , Sundar S. , S Radha , R Meenakumari , G Kaaruniya.
Published: April 2023

Aim: The contagious disease COVID 19 is a recently out-broken pandemic situation which threatens humankind all over the world. Siddha system of medicine is one of the traditional medical systems of India, which has provided a novel remedy for many epidemics like Dengue, Chicken guinea earlier. On evaluating the literature evidence and considering the mortality and severity of the disease, we have attempted to identify the possible inhibition of viral replication by "Karisalai Chooranam" - a polyherbal Siddha formulation which contains herbs like Karisalai (Wedelia chinensis), Thoodhuvelai (Solanum trilobatum), Musumusukai (Melothria maderaspatana) and Seeragam (Cuminum cyminum). The aim of this study was to identify the bioactive components present in Karisalai chooranam and pin down the components that inhibit COVID 19 protease by In Silico molecular docking analysis. Material and methods: The study was performed for the active compounds present in the herbs (Wedelia chinensis - Benzoic acid, Solanum trilobatum- Disogenin, Melothria maderaspatana- β–sitosterol, Cuminum cyminum L- Coumaric acid and Limonene) with three potential targets, PDB id: 6LU7 3-chymotrypsin-like protease (3CLpro), PDB id: 6-NUR RNA dependent RNA polymerase and PDB id: 2AJF Angiotensin-converting enzyme II (ACE2) receptor using Autodock Vina. Key findings: The active phytocomponents present in “Karisalai chooranam” was found to inhibit the target 3CL proenzyme and hereby halt the formation of 16 non-structural proteins (nsp1-nsp16) that are highly essential for viral replication and there by prevents viral survival in the host environment. The phytocomponents also inhibited the target RNA dependent RNA polymerase (PDB)-6NUR RdRp which possess versatile action in mediating nonstructural protein (nsp 12) essential for viral replication. A significant binding against the target Angiotensin-converting enzyme II (ACE2) receptors - PDB- 2AJF was found which was recognized as a binding site for novel coronavirus to cause its pathogenesis. Among the five active components present in the herb, the binding ability of Disogenin and β–sitosterol with COVID19 protease suggests a possible mechanism of protease inhibition and thus preventing viral replication. Significance: The results strongly suggest that phytocomponents of “Karisalai chooranam” may act as a potential therapeutic agent for the management of COVID-19 and related symptoms. Further, the efficacy of the active compounds should be tested in vitro before being recommended as a drug.
Alterations of Thyroid Hormone Levels and the Risks of Diabetic Retinopathy in T2DM
Authors: Ali Alnaji Haider , Omran Rabab , Hamza Hassan Azhar
Published: April 2023

Background: Diabetes mellitus and thyroid disease are linked endocrinopathies. The association between diabetes mellitus complications and thyroid function is characterized by a complicated interdependent interplay that is difficult to understand. Objective: We conducted this study to determine the association between diabetic retina disease (DRD) incidence and normal thyroid hormone levels in T2DM. Methods: Recruit patients in the study, 134 patients with type 2 diabetes and 36 healthy ones with no DM, were screened in the present case-control study. Diabetic retinopathy was tested for all patients, and anthropometric and thyroid functions were assessed. Regression analyses were employed to evaluate the relationship between thyroid hormones and the risk of developing DR. Results: There were significant differences in triiodothyronine (T3) and thyroxine (T4) serum levels among the DR groups and the healthy control. The levels in each TSH and T4 are positively significant between groups of PDR and NDR, while T3 was negatively associated with NPDR. A significant association was found between increasing levels of T3 and the development of severe DR; thus, PDR was less likely to occur in individuals with high T3 levels‎ [OR 0.014(95% CI, 0.001-0.34) P value is 0.009 after adjustment. The risk of PDR had an increased likelihood of developing PDR at the highest levels of serum TSH and T4 [OR 41.07(1.60-1053.1) P= 0.025, OR 65.91(2.10-2067) P= 0.017, respectively). Conclusion: Diabetes retinopathy in euthyroid Iraqi people may be associated with levels of T3 and T4 in the blood. Patients with higher TSH and T4 concentrations had a greater risk of developing sight-threatening PDR in type 2 diabetics.
Geographical Distribution and Future Trend of Publications in the Field of Leather Research
Authors: S Athulya , S. Thanuskodi , B. Shanthi
Published: April 2023

A scientometric study to analyse the research output in the area of leather has been selected as the problem to be investigated. The research output is a good indicator which reflects the trend and structure in any discipline. The analysis of leather research over a period of time indicates the trends in the cognitive structure of the chosen field. The reveals that Asia ranks first in the continents with 4385 publications. In Asia 32 countries have contributed for the leather research. Out of them India stands first with 1666 publications, followed by China with 1473 publications. The study shows that Science Production Index for the top ten Asian countries was calculated. India had the maximum SPI of 14.31 followed by China with a SPI of 12.65.
The Impact of Debt Financing on Startup Profitability
Authors: Zhang Chengzhuo , Nik Azman Nik Hadiyan Binti
Published: April 2023

If a start-up company is unable to grow due to a lack of capital, it is prudent to investigate the possibility of using debt as a source of funding. This study examines the impact of debt financing on the profitability of start-ups using trade-off theory and pecking order theory and uses regression analysis to select factors that are correlated with debt financing structure and profitability for listed companies on the National Equities Exchange and Quotation System (NEEQ) from 2012 to 2021. At the end of the theoretical and empirical analyses, the impact of debt financing on the profitability of start-ups is analyzed and corresponding countermeasures are proposed. Finally, the findings of the study are summarized and the shortcomings of the study and the prospects for future research are outlined. The findings of this study are that debt level structure is negatively related to profitability, indicating that gearing has a negative impact on the profitability of start-ups. In terms of debt type structure, mercantile credit has a positive effect on the profitability of start-ups and bank financing have a detrimental effect on profitability. Overall, debt financing has a negative impact on the profitability of start-ups, but business credit has a positive impact on profitability.
Epidemiological profile of gestational syphilis and congenital syphilis in a reference center in Northeast Brazil: risk factors and trend from 2019 to 2021
Authors: Moraes Alice Rodrigues Barbosa de , Almeida Ana Beatriz Gusmão de , Azevêdo Brenda Labanca da Silva , Freitas Gutemberg Manoel de , Menezes Maria Luiza Bezerra , Barros Rayssa Medeiros de Melo , Coutinho Victoria Lays da Silva
Published: April 2023

Introduction: Syphilis is an infectious systemic disease caused by the bacterium Treponema pallidum. The Amaury de Medeiros Integrated University Health Center in Recife is a reference maternity hospital for high-risk pregnancies and the management of the most common Sexually Transmitted Infections during prenatal care, including Gestational Syphilis and Congenital Syphilis. Objective: To determine the epidemiological profile of the population exposed to these conditions, the rate of Gestational Syphilis detection, the incidence of Congenital Syphilis, and the associated unfavorable outcomes in Amaury de Medeiros Integrated University Health Center between January 2019 and December 2021. Methods: This retrospective cohort study included pregnant women and neonates diagnosed with syphilis at Amaury de Medeiros Integrated University Health Center. Data were collected from the Notification/Investigation Forms for Gestational Syphilis and Congenital Syphilis, between January 2019 and December 2021. Results: At Amaury de Medeiros Integrated University Health Center, 463 cases of Gestational Syphilis and 296 of Congenital Syphilis were reported. During the three-year study, 4444, 4360, and 4265 live births were recorded, confirming the Gestational Syphilis detection rates — 33.30, 36.92, and 36.10 per 1000 live births, with the incidence of Congenital Syphilis being 26.1, 21.33, and 20.39 per 1000 live births. Pregnant women in their third trimester who were brown, had incomplete primary education, and lived in an urban area were the main sociodemographic variables. In total, 217 (73.3%) patients were diagnosed with Gestational Syphilis during or after delivery, indicating a low prenatal coverage (70.6%). In terms of the progression of Congenital Syphilis, unfavorable outcomes was found in 40 (13.5%) patients, including 16 (40%) abortions, 10 (25%) stillbirths, nine (22.5%) deaths from Congenital Syphilis, and 5 (12.5%) deaths from other causes. Conclusion: Gestational Syphilis detection rates and Congenital Syphilis incidence remain alarming, with abortions and stillbirths being the most common unfavorable outcomes. To change the dramatic situation of Congenital Syphilis in Brazil, the associated factors point to a poor quality of prenatal care and an urgent need to change public policies for pregnant women and newborns, in conjunction with socioeconomic assistance.
Delimitação da área de reservatório de água utilizando técnicas de sensoriamento remoto no semiárido do Brasil
Authors: Almeida Debora Natália Oliveira de , Araújo Diêgo Cezar dos Santos , Soares Débora Rodrigues , Maia Francisco Marcelo de Alencar , Montenegro Suzana Maria Gico Lima , Santos Sylvana Melo dos , Oliveira Leidjane Maria Maciel de
Published: April 2023

As técnicas de sensoriamento remoto são de fundamental importância para investigar as alterações ocorridas no mosaico terrestre ao longo dos anos e contribuir para tomadas de decisão cada vez mais eficientes em gestão ambiental e hídrica. Os objetivos deste artigo foram detectar, delimitar e quantificar a área hídrica do reservatório Poço da Cruz, localizado em Ibimirim, Pernambuco, Semiárido do Brasil, com modelagem baseada em imagens multiespectrais do satélite Landsat 8/OLI datadas de 2015 a 2020, bem como relacioná-la com dados de precipitação pluvial média do produto CHIRPS. Para tanto, foi modelado o Índice de Água por Diferença Normalizada Modificado (MNDWI), com o qual se geraram os mapas temáticos georreferenciados e extraíram-se apenas os pixels representados por valores espectrais positivos, que representam alvos hídricos. Utilizou-se o software de livre acesso QGIS 2.18.16 para todas as etapas de processamento digital de imagens e conexão com bancos de dados complementares para a elaboração dos mapas temáticos. Nos resultados foram evidenciadas as mudanças na distribuição espacial do Poço da Cruz, analisadas com a utilização de dados de precipitação com base no produto CHIRPS, permitindo melhor compreensão do comportamento da pluviometria na região e sua influência. O MNDWI foi condizente com o produto de precipitação do CHIRPS, e ficou evidente a variação área hídrica do reservatório com relação à ocorrência de eventos chuvosos, especialmente em outubro/2017 (mínimos valores) e outubro/2020 (máximos valores).
Management of Supracondylar Fractures of the Humerous in Children
Authors: Khan Asghar , Akhtar Sayed Sohail , Ahmad Saeed , Tippu Abdul Rauf , Qureshi Nadeem , Lakhani Sartaj
Published: April 2023

Background: Supracondylar humeral fractures (SFH) are the most common fractures of the pediatric elbow, having a peak frequency between the ages of four and nine years. The majority of surgical therapy is percutaneous pinning and closed reduction. The present study aimed to determine the outcome of close reduction and percutaneous pinning in managing the supracondylar humeral fractures in children. Patients and Methods: A total of 64 children presented with supracondylar humeral fractures to the Orthopaedics Unit of Bacha Khan Medical Complex, Swabi during the period from 16th February 2022 to 15th November 2022. Children with supracondylar humerus fractures of completely displaced (Gartland Type III) were enrolled whereas neurovascular injury related to open or closed Gartland type-III fracture were excluded. Under general anesthesia, close reduction was accomplished, and the elbow was immobilized in extension by the implantation of two plaster slabs. The type of fracture, injury pattern, time from injury to final therapy, surgical treatment, and consequences were all recorded. Results: The overall mean age was 4.89±3.2 years. Of the total 64 SFH cases, there were 52 (81.3%) male and 12 (18.7%) females. Out of 52 (81.3%) children with pulseless hands, the incidence of Gartland type III and IV was 15.4% (N=8) and 84.6% (N=44) respectively. Out of 52 cases, there were 19 (36.5%) cold hands and 33 (53.5%) warm hands. The overall mean time between injury and presentation was 3.8±2.4 hours. The incidence of patients undergoing autologous interposition venous grafting, vascular reconstruction, and segmental resection and primary anastomosis was 25% (N=16), 59.4% (N=38), and 15.6% (N=10) respectively. There were no amputations, fasciotomies, re-explorations, or long-term ischemic sequelae. Conclusion: The present study found that close reduction and immobilization with two slabs is a safer and effective method for superior outcome of managing supracondylar humeral fractures in uncomplicated type III injuries as compared to flexion approach. Additionally, Rapid vascular exploration might effectively treat both cold and warm pulseless hands. Keywords: Supracondylar humeral fractures, Management, Children, Close reduction approach
Frequency of Transfusion Transmitted Infections in Healthy Blood Donors in a Tertiary Care Hospital
Authors: Shaikh Farhan Ahmed , Noureen Aqsa , Shaikh Abdul Rehman Khalil , Baloch Sana Lund , Waqas Aisha , Saboor Rukhsana , Aamir Kiran , Ramzan Aamir
Published: April 2023

Objective: To determine transfusion transmitted infectious disease (TTI) pattern in potential healthy replacement donors. Study Design: Cross sectional study Place and Duration: Diagnostic and Research Laboratory Liaquat University of Medical and Health Sciences Jamshoro, Hyderabad. Jan-2022-Dec 2022 Methods: Total 14,355 replacement donors of age 18-55 years were selected in this study as per inclusion criteria, which comprised of 25 questionnaire, evaluating donors for history of Injections, medicines, time since last donation, tattoos, not feeling well, dental work, sexual relationships, history of malaria / T.B, surgery, jaundice vaccination positive viral markers in the past followed by physical examination. SPSS 24.0 was used to analyze all data. Results: There were 9635 (67.1%) males and 4720 (32.95) females in this study. Among all, 42.8% cases had age 18-25 years, 26.8% cases had 26-30 years, 16.6% cases had 31-35 years and 13.7% patients were from age group 36-55 years. Majority of the donors 32.3% had blood group B positive, followed by O positive in 29.9%, 22% donors had A positive and AB positive blood group found in 8.7% cases. According to screening results, most common infection was Hepatitis B Core Antibody found in 10% cases, anti-HCV found in 2.17% cases, HBsAg in 0.3% cases, ICT malaria in 0.05% cases, RPR 0.41% and HIV 1&2 in 0.1% cases. Conclusion: HB core total antibody showed highest positivity in replacement donors despite stringent donor selection criteria, followed by Anti HCV. Syphilis, HBsAg, HIV and malaria showed lowest prevalences. Keywords: Blood Donors, HCV, HBV, ICT Malaria
Frequency of Gastrointestinal Signs and Symptoms in Patients with Dengue Fever in Tertiary Care Hospital
Authors: Abrar Taqdees , Selamat Tayyeba , Abbasi Anwar Hussain , Cheema Hafsa Javaid , Ahmed Shazma , Zaka Maryam
Published: April 2023

Objective: The objective behind this study was to determine the frequency of gastrointestinal signs and symptoms in patients with dengue fever in tertiary care hospital Methods: A cross sectional observational study was conducted on all adult patients diagnosed with dengue disease after taken informed consent from the patients and approval from the ethical committee of the hospital. All these patients were evaluated for the presence or absence of gastrointestinal (GI) manifestations. Those who had GI symptoms were further evaluated for the frequency of different types of GI symptoms. All baseline and clinical data were taken using a structured questionnaire and then entered & analysed using SPSS v. 26. Results: A total of 174 patients who were dengue virus positive were included for final analysis. Overall mean age and SD was 29.22±8.14 years and majority belongs to young age group, ≥16 – 40 years (60.11%, n = 104). Most of our study participants were males (75.86%, n = 132). Hypertension was the most common comorbid condition observed in our study participants (12.06%, n = 21). The overall prevalence of GI manifestations in our study who were dengue positive was 62.64% (n = 109). The most common GI symptom was presence of nausea/vomiting (70.64%, n = 77). Conclusion: The prevalence of GI manifestations in patients with dengue is quite high. Nausea/vomiting was the most common GI manifestation while patients with hepatomegaly and GI bleeding were also prevalent. Keywords: Dengue fever, gastrointestinal symptoms, clinical manifestation, Pakistan
Decreasing Complications in Distal Hypospadias Surgery, with Single Stage Repairs
Authors: Aziz Asif , Khan Mansoor , Ullah Hidayat , . Obaidullah
Published: April 2023

Introduction: Hypospadias is one of the most common congenital anomalies of male population. The diversity of presentation, and the evolution of its surgical management have rendered the acceptance of a standard protocol. This article reports on the outcomes and complications of single stage tubularization for distal and midshaft hypospadias with no or mild ventral curvature. Material and Methods: A total of 128 patients, with age range of 8 months to 28 years were included. All had distal or midshaft hypospadias with no or mild ventral curvature, with no previous procedures. All patients undergone two types of surgical repairs, Glanular Approximation Procedure and Tubularized Incised Plate urethoplasty. Results: Most patients had smooth postoperative recovery. All patients were followed for six months to one year. Major complication of concern were urethra-cutaneous fistula in 8 (6%) and glanular dehiscence in 2 (2%) of patients, which required surgical closure. Practical Implications: The practical implications of hypospadias surgery include improved urinary function, reduced risk of infections, improved sexual function, and improved psychological well-being. Keywords: Hypospadias, Tubularization, Urethroplasty, Glanular approximation procedure, Incised Plate Urethroplasty
Kirschner Wire Fixation Versus Mini Plate Fixation in Multiple Metacarpal Shaft Fractures of Hand to Compare Early Range of Motion in Hand
Authors: Farooq Muhammad Zubair , Essa Muhammad Asghar , . Inamullah , Gul Yousaf , Ullah Shafaat
Published: April 2023

Background: Metacarpal bone plays vital role in supporting motor functions of the human palm and is subjected to frequent stress. If a fracture of the metacarpal bone occurs, it can destabilize the palm, disrupt muscular-tendon tension, impair functions of palm joints, and have adverse impacts on the daily life and work of the patient. Objectives: To compare early range of motion (ROM) in hand following K-wire fixation versus mini plate fixation in patients with multiple metacarpal shaft fractures. Methods: Cross-sectional analysis of patients with multiple metacarpal shaft fractures was done at Mufti Mehmood Memorial Teaching Hospital, between 2021 and 2022, and comprised 108 patients managed with K-wire Fixation and mini plate fixation. The success rate as well as clinical outcome of both techniques was measured as early ROM in the hand, which was assessed at eight weeks post-surgery using DASH scores. Results: Majority of patients (p<0.05) were males (73.14%), common fractures (p<0.05) were closed type (75.03%), right sided (62.96%) and common cause of injury (p<0.05) was traffic accidents (n=48), industrial accidents (n=13), fall (n=12), agriculture accidents (n=12) and assault (n=10). Our findings revealed that occurrence of complications was significantly higher among the patients of group K-wire fixation (11.11%) than mini wire fixation (6.48%) and assessment of ROM through DASH score system of mini plate fixation was better than K-wire fixation. Practical implication The surgeons will confidently apply mini plate fixation in patients with multiple shaft fractures rather than K-wire fixation after reading this article. Conclusion: Mini plate fixation may be more effective than K-wire fixation in restoring early ROM in the hand following surgery for multiple metacarpal shaft fractures. Keywords: DASH scoring; Palm fracture; Range of motion; Shaft fracture.
IMPACT DE LA RUPTURE DES STOCKS DES PRODUITS BRASSICOLES SUR LE COMPORTEMENT DES CLIENTS DANS UN SYSTEME CONCURENCIEL DANS LA VILLE DE GOMA. CAS DE LA BRALIMA SARL DE JANVIER 2012 A OCTOBRE 2014
Authors: Micky KAFUMBAMIRA BAMENYIRWE Paul
Published: April 2023

Ce travail traite de l’impact de la rupture de stocks des produits brassicoles sur le comportement des clients dans un système concurrentiel cas de la BRALIMA SARL/ Dépôt de Goma.

Le problème trouvé était de savoir qu’est-ce qui est à la base des ruptures des stocks des produits BRALIMA sur le marché de la ville, d’où ma question posée : quel est l’impact de la rupture des stocks des produits brassicoles sur le comportement de ses clients ? on a émis comme hypothèse : la rupture des stocks des produits brassicoles aurait un impact négatif sur le comportement de ses clients.

L’objet assigné à ce travail était d’évaluer l’impact de la rupture des stocks de BRALIMA SARL/Goma dans l’optique logistique. J’ai eu comme résultats :

A la question de savoir les causes de ruptures des stocks des produits brassicoles de la BRALIMA SARL Dépôt de Goma 70% des enquêtés sur l’assemble affirment connaitre les causes de ruptures de  stocks et occupe la 1ère position, 17% des enquêtés nient connaitre les causes de ruptures de stocks des produit et 17% ont répondu je ne sais pas. On a confirmé l’hypothèse nulle.

A la question de savoir les conséquences y afférentes, les résultats de nos recherches ont poussé à confirmer  l’hypothèse nulle.

En fin, à la question de proposer des pistes de solution, la comparaison du Khi carré a infirmé l’hypothèse nulle car le Khi carré existant entre les valeurs dépendantes et indépendantes ayant donné 2,9 supérieurs au Khi carré tabulaire.
Assesment of erythroferrone levels in neonates with anaemia of prematurity
Authors: El-Hawy Mahmoud Ahmed , Mohamed Mohamed Soliman Soliman , Refat Shimaa Abdelsattar , Ashour Noha M.
Published: April 2023

Background: The anemia of prematurity is caused by untimely birth occurring before placental iron transport and fetal erythropoiesis are complete. Objective: To determine the serum levels of erythroferrone and their relation to the anaemia of prematurity. Patients and methods: This study was case control study carried out in the the Pediatric Department, Faculty of Medicine, Menoufia University. This study included two groups; the first group included newborns of both sexes with anemia of prematurity admitted to the NICU during the study period, the 2nd group included group of healthy newborns. all participants were subjected to history taking, general examination, Local examination, Abdominal examination and Laboratory investigations including complete blood count (CBC), and blood film, C reactive protein (CRP), Blood culture when needed, Kidney functions tests: including serum creatinine and urea, Liver function tests: including serum aspartate aminotransferase (AST) and alanine aminotransferase (ALT), Hepcidin level and Erythroferrone. Results: There was no statistically significant difference in liver, renal functions, CRP. Hepcidin showed significant decrease in diseased group when compared to the control group. Free erythroferrone levels showed significant increase in diseased group when compared to the control group.
PMO E O SUCESSO EM PROJETOS: UM ESTUDO SOBRE EMPRESAS BRASILEIRAS DE GRANDE PORTE
Authors: Prado Edmir Parada Vasques , Mancini Mônica
Published: April 2023

Introdução: Dentre as unidades organizacionais que contribuem para o sucesso de projetos, destaca-se o escritório de gerenciamento de projetos (PMO). Entretanto, há poucos trabalhos na literatura que consideram a realidade brasileira e, mais ainda, realizados por meio de um survey. Assim, esta pesquisa tem como objetivo analisar a relação entre o nível de responsabilidade do PMO e o sucesso em projetos. A revisão bibliográfica descreve as características do PMO e o sucesso em projetos. Método: A pesquisa caracteriza-se por ser um estudo descritivo, quantitativo e transversal. A amostra é composta por 100 profissionais que atuam em PMOs, em organizações brasileiras privadas de grande porte. Optou-se por uma amostra não probabilística, com procedimento de amostragem por conveniência. A coleta de dados foi realizada no primeiro trimestre de 2021. Resultados: Somente uma hipótese foi confirmada, ou seja, PMOs com maior nível de responsabilidade tiveram uma frequência de sucesso maior no médio prazo. Conclusão: a pesquisa sugere que organizações que buscam desenvolver e aprimorar suas equipes de projeto devem ter PMOs com maior nível de responsabilidade, ou seja, PMOs com maior nível de autonomia.
Realidade fake, sofrimento real: o cidadão de bem bolsonarista neoliberal a partir do pensamento de Adorno e Chaui
Authors: Maeso Benito Eduardo Araujo
Published: April 2023

O artigo busca, por meio do recurso aos conjuntos teóricos de Theodor Adorno e Marilena Chaui, investigar alguns elementos presentes na formação do que pode ser denominado realidade fake, na qual o falso é o índice da verdade. Este modo de vida caracteriza-se pela disposição de indivíduos e grupos sociais em, por meio da recusa deliberada entre o verdadeiro e o falso, aceitar para si mesmos e buscar impor aos demais relações sociais trespassadas por uma fusão de autoritarismo, ódio ao conhecimento e competição desenfreada de todos contra todos, conciliando de forma eficaz a lógica neoliberal com modelos antidemocráticos e subjetividade paranoica. Tais formas sociais são características, por exemplo, do bolsonarismo como representação do novo radicalismo de direita que ocupa a cena política brasileira atualmente.
Mein Kampf: um texto nazista em seus dois momentos – uma abordagem do escrito de Hitler como Fonte Histórica
Authors: Barros José D'Assunção
Published: April 2023

O artigo procura abordar o livro Mein Kampf, de Adolf Hitler, como fonte histórica que permite dar a compreender aspectos diversos do pensamento nazista, mostrando as potencialidades historiográficas desta fonte, suas intertextualidades, estratégias discursivas, recepções, além das relações que devem ser estabelecidas entre texto e contexto histórico. Ao final do artigo, utiliza-se a metáfora do acorde musical para a compreensão de que o pensamento nazista é produzido por uma combinação de notas que podem ser percebidas nesta e em outras fontes históricas relacionadas ao nazismo alemão e ao pensamento hitlerista
A agência político-ontológica da arte indígena contemporânea
Authors: Cernicchiaro Ana Carolina
Published: April 2023

A produção de artistas indígenas não apenas coloca em cheque a universalidade da história da arte e seus dispositivos históricos e estéticos de invisibilidade, como também problematiza o pensamento utilitarista, etnocêntrico e antropocêntrico do “povo da mercadoria”, mostrando que racismo e antropocentrismo, genocídio e ecocídio, são dois lados de uma mesma moeda, tentativas de justificar a dominação e a destruição da natureza, de invalidar a relação de pertencimento que os povos originários têm com a terra, o fazer corpo com a terra, com o solo e com o planeta. A estética cosmopolítica da arte indígena contemporânea nos ensina, assim, formas outras de resistência e de existência, concepções outras de ser e de mundo, de ser no mundo, de ser-com o mundo.
Cómo Pensar la Revuelta
Authors: Balas Eliza Mizrahi
Published: April 2023

Este trabajo toma como punto de partida la exposición Sublevaciones, del filósofo Georges Didi-Huberman, para establecer el montaje como una condición crítica del pensamiento que nos permite desocultar los estatutos estéticos, políticos e ideológicos de la representación visual de las revueltas. Sobre todo, porque analizar los modos de lo visible de la revuelta desde sus procesos de producción y circulación de las imágenes implica reconocer los desordenamientos o desgarros que se producen en dicho orden; lo que nos incita a pensar sobre otros regímenes de visibilidad de lo político. Desde este lugar entonces, pensar la revuelta desde sus imágenes para tomar posición frente a ellas y ver más allá en un ejercicio, tanto visual como político, que interrogue a la propia mirada - ¿cómo miramos una imagen?, ¿qué nos mira en ella?, ¿cómo elevar el pensamiento acerca de la imagen? - para poner en escena lo visible y loinvisible de la vida de las imágenes.
Em nome da realidade: fé, mito e violência nas configurações do capitalismo contemporâneo
Authors: Honesko Vinícius
Published: April 2023

O presente ensaio visa a questionar as estruturas constitutivas das formas de da realidade no capitalismo contemporâneo. Para tanto, o texto se subdivide em três partes: a primeira, a partir de uma breve leitura de questões ligadas ao problema epistemológico na física quântica, apresenta o problema da constituição da realidade e de sua conformação como mito; a segunda, investiga como a figura do precariado passa a ser fundamental na arregimentação dessa realidade, sobretudo a partir da lógica constitutiva de uma das formas do assim chamado neoliberalismo contemporâneo (aproximadamente, a partir de 1980 até o presente); a terceira, compreende como a fundamentação dessa realidade se dá, muitas vezes de forma violenta, a partir de um embate sobre a própria condição de possibilidade de sentido para o mundo.
SAÚDE MENTAL NO ENSINO SUPERIOR: REVISÃO DE LITERATURA
Authors: Lima Vivian Daniele de , Meira Costa Ailana Garcia , Iennaco de Vasconcelos Maria Luiza , Lourenço Lelio Moura
Published: April 2023

A saúde mental de universitários é uma temática crescente na literatura científica, principalmente devido ao aumento da prevalência de transtornos psicológicos. Com o intuito de aprofundar aspectos como: a vulnerabilidade, fatores de risco e de proteção e consequências para a saúde dos estudantes foi realizada uma revisão de literatura das publicações dos últimos 10 anos.  Elegeram-se as seguintes bases de dados: PsycInfo, Dialnet, Scielo Brasil, PePSic; e a Web of Science e analisados 161 artigos. Contatou-se que Brasil, Estados Unidos e Espanha foram os países com maior número de publicações. A metodologia adotada pela maioria das pesquisas foi a quantitativa, destacando-se delineamentos descritivos, experimentais, correlacionais e transversais. A maioria das publicações tiveram como público-alvo estudantes das áreas de saúde e verificou-se uma necessidade de validação de instrumentos específicos para o contexto acadêmico. Estudos futuros podem ampliar as discussões acerca do suicídio acadêmico e também discutir possibilidades de prevenção, propostas de intervenção e a saúde mental em estudantes de mestrado e doutorado.
Pastoral livestock market integration amidst improvements in physical and communication infrastructure: Evidence from northern Kenya
Authors:   Department of Agricultural and Resource Economics, Jomo Kenyatta University of Agriculture and Technology, Kenya & African Agency for Inclusive Innovations., Chelanga Philemon , Jensen Nathaniel ,   Independent Researcher, Mutuku Muendo Kavoi ,   Department of Agricultural and Resource Economics, Jomo Kenyatta University of Agriculture and Technology, Kenya.
Published: April 2023

This article analyses the level of integration in pastoral markets in Kenya using high-frequency data generated through a crowdsourcing endeavour. The vector error-correction model framework was used to estimate the causal relationships between the short- and long-run market price. The results indicate that a higher proportion of price variation in larger markets in the region was due to market price shocks, while variation in the smaller markets originated from the larger markets. Weekly adjustments and the convergence of prices on a long-run equilibrium after experiencing shocks were also observed. Price transmission was also evident between markets operating along different trading routes. However, markets located close to production catchments exhibited lower price trends, despite being connected. These results suggest a strong influence of the recent infrastructural investments on price transmission between markets in the region. The findings imply that more investments would enhance the competitive trading environment and reduce unidirectional price transmission.
Clinical Implications of Hyperleukocytosis/Leukostasis Syndrome
Authors:   Department of Hematology, Faculty of Medical Laboratory Sciences, Port Sudan Ahlia College, Sudan, Bashir Bashir Abdrhman
Published: April 2023

The unusual leukemia presentation known as hyperleukocytosis (white blood cell count >100×109/L) is linked to a higher risk of premature death. Leukostasis, a syndrome brought on by the sludging of circulating leukemic blasts in the microcirculation, is one of its secondary symptoms, which can take many different forms. This minireview on hyperleukocytic leukemia highlights the pathogenesis, clinical signs, and treatment options for these abnormalities. Cytoreduction, suppressing tumor lysis, and leukapheresis are appropriate therapies for this medical emergency when leukostasis and hyperviscosity syndrome are prominent.