bluuebunny/crossref_metadata_2025 huggingface dataset:
Liquid biopsy for cancer management: a revolutionary but still limited new tool for precision medicine
Authors: Arechederra María , Ávila Matías A. , Berasain Carmen
Published: May 2020

The term liquid biopsy is used in contraposition to the traditional “solid” tissue biopsy. In the oncology field it has opened a new plethora of clinical opportunities as tumor-derived material is shedded into the different biofluids from where it can be isolated and analyzed. Common biofluids include blood, urine, saliva, cerebrospinal fluid (CSF), pleural effusion or bile. Starting from these biological specimens several analytes can be isolated, among which we will review the most widely used: circulating tumor cells (CTCs), circulating tumor DNA (ctDNA), circulating tumor RNA (ctRNA), proteins, metabolites, and exosomes. Regarding the nature of the biomarkers it will depend on the analyte, the type of tumor and the clinical application of the liquid biopsy and it includes, somatic point mutations, deletions, amplifications, gene-fusions, DNA-methylated marks, tumor-specific miRNAs, proteins or metabolites. Here we review the characteristics of the analytes and the methodologies used for their isolation. We also describe the applications of the liquid biopsy in the management of patients with cancer, from the early detection of cancers to treatment guidance in patients with advanced tumors. Finally, we also discuss some current limitations and still open questions.
Variante en gen HARS detectada en exoma clínico: etiología de neuropatía periférica tras más de 20 años sin diagnóstico
Authors: Lahoz Alonso Raquel , Sienes Bailo Paula , Capablo Liesa Jose Luis , Álvarez de Andrés Sara , Bancalero Flores Jose Luis , Izquierdo Álvarez Silvia
Published: May 2020

Objetivos

Describimos un caso con enfermedad de Charcot Marie Tooth axonal tipo 2W, trastorno neurólogico caracterizado por una neuropatía periférica, que afecta principalmente a las extremidades inferiores y provoca dificultades en la marcha y deterioro sensitivo-motor distal.

Presentación del caso

Es un caso en el que la aplicación de las nuevas técnicas de secuenciación masiva (NGS) a través del exoma clínico en los laboratorios de genética permitió detectar la presencia de variantes candidatas de la clínica del paciente.

Conclusiones

La variante detectada en el gen HARS podría apoyar la causalidad en el contexto clínico del paciente tras 20 años sin diagnóstico y con empeoramiento de la clínica.
Critical appraisal and meta-analysis of biological variation studies on glycosylated albumin, glucose and HbA1c
Authors: Ricós Carmen , Fernández-Calle Pilar , Gonzalez-Lao Elisabet , Simón Margarida , Díaz-Garzón Jorge , Boned Beatriz , Marqués-García Fernando , Minchinela Joana , Perich Maria Carmen , Tejedor-Ganduxé Xavier , Corte Zoraida , Aarsand Aasne K. , Aslan Berna , Carobene Anna , Coskun Abdurrahman , Sandberg Sverre
Published: May 2020

Objectives

Numerous biological variation (BV) studies have been performed over the years, but the quality of these studies vary. The objectives of this study were to perform a systematic review and critical appraisal of BV studies on glycosylated albumin and to deliver updated BV estimates for glucose and HbA1c, including recently published high-quality studies such as the European Biological Variation study (EuBIVAS).

Methods

Systematic literature searches were performed to identify BV studies. Nine publications not included in a previous review were identified; four for glycosylated albumin, three for glucose, and three for HbA1c. Relevant studies were appraised by the Biological Variation Data Critical Appraisal Checklist (BIVAC). Global BV estimates were derived by meta-analysis of BIVAC-compliant studies in healthy subjects with similar study design.

Results

One study received BIVAC grade A, 2B, and 6C. In most cases, the C-grade was associated with deficiencies in statistical analysis. BV estimates for glycosylated albumin were: CVI=1.4% (1.2–2.1) and CVG=5.7% (4.7–10.6), whereas estimates for HbA1c, CVI=1.2% (0.3–2.5), CVG=5.4% (3.3–7.3), and glucose, CVI=5.0% (4.1–12.0), CVG=8.1% (2.7–10.8) did not differ from previously published global estimates.

Conclusions

The critical appraisal and rating of BV studies according to their methodological quality, followed by a meta-analysis, generate robust, and reliable BV estimates. This study delivers updated and evidence-based BV estimates for glycosylated albumin, glucose and HbA1c.
A nonlinear dynamical approach to analysis of emotions using EEG signals based on the Poincaré map function and recurrence plots
Authors: Khodabakhshi Mohammad Bagher , Saba Valiallah
Published: May 2020

Dynamic variations of electroencephalogram (EEG) contain significant information in the study of human emotional states. Transient time methods are well suited to evaluate short-term dynamic changes in brain activity. Human affective states, however, can be more appropriately analyzed using chaotic dynamical techniques, in which temporal variations are considered over longer durations. In this study, we have applied two different recurrence-based chaotic schemes, namely the Poincaré map function and recurrence plots (RPs), to analyze the long-term dynamics of EEG signals associated with state space (SS) trajectory of the time series. Both approaches determine the system dynamics based on the Poincaré recurrence theorem as well as the trajectory divergence producing two-dimensional (2D) characteristic plots. The performance of the methods is compared with regard to their ability to distinguish between levels of valence, arousal, dominance and liking using EEG data from the “dataset for emotion analysis using physiological” database. The differences between the levels of emotional feelings were investigated based on the analysis of variance (ANOVA) test and Spearman’s statistics. The results obtained from the RP features distinguish between the emotional ratings with a higher level of statistical significance as compared with those produced by the Poincaré map function. The scheme based on RPs was particularly advantageous in identifying the levels of dominance. Out of the 32 EEG electrodes examined, the RP-based approach distinguished the dominance levels in 23 electrodes, while the approach based on the Poincaré map function was only able to discriminate dominance levels in five electrodes. Furthermore, based on nonlinear analysis, significant correlations were observed over a wider area of the cortex for all affective states as compared with that reported based on the analysis of EEG power bands.
Incorporation of silver stearate nanoparticles in methacrylate polymeric monoliths for hemeprotein isolation
Authors: Alzahrani Eman
Published: May 2020

A unique method was used to synthesize extremely stable silver stearate nanoparticles (AgStNPs) incorporated in an organic-based monolith. The facile strategy was then used to selectively isolate hemeproteins, myoglobin (Myo) and hemoglobin (Hb). Ethyl alcohol, silver nitrate, and stearic acid were, respectively, utilized as reducing agents, silver precursors, and capping agents. The color changed to cloudy from transparent, indicating that AgStNPs had been formed. AgStNP nanostructures were then distinctly integrated into the natural polymeric scaffold. To characterize the AgStNP–methacrylate polymeric monolith and the silver nanoparticles, energy-dispersive X-ray (EDX), scanning electron microscopy (SEM), and Fourier-transform infrared (FT-IR) spectroscopy were used. The results of the SEM analysis indicated that the AgStNP–methacrylate polymeric monolith’s texture was so rough in comparison with that of the methacrylate polymeric monolith, indicating that the extraction process of the monolith materials would be more efficient because of the extended surface area of the absorbent. The comparison between the FT-IR spectra of AgStNPs, the bare organic monolith, and AgStNP–methacrylate polymeric monolith confirms that the AgStNPs were immobilized on the surface of the organic monolith. The EDX profile of the built materials indicated an advanced peak of the Ag sequence which represented an Ag atom of 3.27%. The results therefore established that the AgStNPs had been successfully integrated into the monolithic materials. Extraction efficiencies of 92% and 97% were used to, respectively, recover preconcentrated Myo and Hb. An uncomplicated method is a unique approach of both fabrication and utilization of the nanosorbent to selectively isolate hemeproteins. The process can further be implemented by using other noble metals.
Investigation of structural performance subjected to impact loading using finite element approach: case of ship-container collision
Authors: Prabowo Aditya Rio , Laksono Fajar Budi , Sohn Jung Min
Published: May 2020

Transporting mass products from one country to others is essential activities in industrial cycle. Ships are selected as reliable carriers for this objective considering traveling time and operational cost. During its operational, accidental events such as storm, high tide and bad weather may cause the products which are usually packed in freight containers fall into sea, and impacts the ship structure. In this situation, casualties on both involved structures can be detrimental. This work analyzes a series of ship-container collision in maritime territory in order to investigate resulting structural phenomena. The finite element approach is selected to solve the designed collision cases where the discussion is directed to selected crash-worthiness criteria. Impact speed between ship and container structures is chosen as the main parameter in the designed scenario by judging whether this parameter is a good representative of sea state. Overall results indicate that the indication for container rebounding after impact was high. It was followed by a significant increment of the internal energy after higher velocity, which was more than 5 m·s−1, had been applied to the scenario. Quantification of specific structural performance suggests that approximately more than 80% of the damage occurrs on the contacted area of the container structure.
Characteristic feature analysis of continuous optimization problems based on Variability Map of objective function for optimization algorithm configuration
Authors: Agasiev Taleh
Published: May 2020

Advanced optimization algorithms with a variety of configurable parameters become increasingly difficult to apply effectively to solving optimization problems. Appropriate algorithm configuration becomes highly relevant, still remaining a computationally expensive operation. Development of machine learning methods allows to model and predict the efficiency of different solving strategies and algorithm configurations depending on properties of optimization problem to be solved. The paper suggests the Dependency Decomposition approach to reduce computational complexity of modeling the efficiency of optimization algorithm, also considering the amount of computational resources available for optimization problem solving. The approach requires development of explicit Exploratory Landscape Analysis methods to assess a variety of significant characteristic features of optimization problems. The results of feature assessment depend on the number of sample points analyzed and their location in the design space, on top of that some of methods require additional evaluations of objective function. The paper proposes new landscape analysis methods based on given points without the need of any additional objective function evaluations. An algorithm of building a so-called Full Variability Map is suggested based on informativeness criteria formulated for groups of sample points. The paper suggests Generalized Information Content method for analysis of Full Variability Map which allows to get accurate and stable estimations of objective function features. The Sectorization method of Variability Map analysis is proposed to assess characteristic features reflecting such properties of objective function that are critical for optimization algorithm efficiency. The resulting features are invariant to the scale of objective function gradients which positively affects the generalizing ability of problems classification algorithm. The procedure of the comparative study of effectiveness of landscape analysis algorithms is introduced. The results of computational experiments indicate reliability of applying the suggested landscape analysis methods to optimization problem characterization and classification.
To be Black, Queer and Radical: Centring the epistemology of Marielle Franco
Authors: Loureiro Gabriela Silva
Published: May 2020

The aim of this article is to pay tribute to Marielle Franco, a Brazilian LGBTQ+ Black activist from the favela who was brutally executed in March 14, 2018. Taking Marielle’s life and death as a case study, I will demonstrate how she embodied Black feminist theory and practice and how her execution can be better addressed by situating it within the context of spatialities of race and the necropolitical governance of Rio de Janeiro.
Il prologo della Lettera a Erodoto di Epicuro: sul testo di Diog. Laert. x 35-7
Authors: Lapini Walter
Published: May 2020

Three textual proposals on Diog. Laert. x 35-7 =Epicur. ep. Hrdt. 35- 7: (1) read 36 έν <δέ> τῇ μνήμῃ with Von der Muehll, giving <δέ> a strong oppositive sense; (2) transpose 36 έπεί καί τοṽ (τῷ) τετελεσιονργῃγένου (-ῳ) (…) δύνασθαι χρῇσθαι after 35 δεῖ μνῃμονεύειν (3) read 37 παρεγγνᾷ instead of παρεγγνῷν, retaining έγγαρλῃνίζον with the majority of mss.
„Was jede Seele sucht und worumwillen sie alles tut“
Authors: Ferber Rafael
Published: May 2020

The article first (i) gives an exegesis of the famous passage in the Republic, 505d11-506a2. Attention is drawn to the fact that the principle that every soul does everything for the Good (panta prattei) can be translated in two ways: Every soul does everything for the sake of the Good, or goes to all lengths for the sake of the Good. Depending on the different translations, we have a different picture of the platonic Socrates in the Republic, an intellectualistic Socrates for whom pure irrational desires do not exist, or a Socrates who also accepts irrational desires. The article favours the first picture. Then it (ii) attempts to show that we can elucidate two dark points in the Socratic thesis that the Good is what every soul pursues and for which every soul does everything, with the help of Aquinas. Finally, the article (iii) outlines three substantive answers to the question ``What is the Good?'' - the henological, the perfectionist and the structuralist - and shows that these three answers lead into a trilemma. Instead of advancing a new answer, the article suggests an uncontroversial formal starting point for an answer to this question.
Aristotelian Reminiscences in Philo
Authors: Glucker John
Published: May 2020

The first part of this article deals with two cases of what seems to be Aristotelian reminiscences in the works of Philo of Alexandria. A passage in Quod deterius and a passage in De agricultura show close verbal reminiscences to two passages in Book i of Nicomachean Ethics; and a passage in De migratione Abrahami shows verbal reminiscences to two passages in Book ii. Since it appears from Book v of De finibus that Antiochus of Ascalon had already read at least parts of Nicomachean Ethics; and the first commentator on the Ethics, Aspasius, has clear references to some predecessors who had already read and discussed this work, I argue for the possibility that Philo also read the Nicomachean Ethics. The second part deals with an almost forgotten book review by Jacob Freudenthal, published in 1875, which argues that Philo was familiar with various parts of the Aristotelian corpus as we have it. I examine his detailed arguments and conclude that, with all due respect to a great scholar, they do not seem to prove his point.
Concezioni stoiche e idee platoniche
Authors: Bonazzi Mauro
Published: May 2020

Aim of this paper is to show how Middle Platonist philosophers adapted Stoic epistemology to their own Platonist metaphysics. More precisely the discussion focuses on the key notion of ennoia (conception).Middle Platonists argue against the hypothesis that conceptions have an empirical origin and claim that an ennoia is what remains of the pre-natal vision of the ideas. According to them, it is only through metaphysics that a theory of knowledge can adequately be grounded. The second part of the paper delves into the limits of such a claim. The possibility of getting a proper knowledge of the ideas raises a problem, for if the ennoiai are grounded on the ideas, but the ideas are not object of a proper knowledge, we run the risk of not having a proper criterion anymore. On these grounds, we would not be able to account for the process of knowledge.
Dalla tecnica all’etica: argomentazioni peirastiche in Lachete, Carmide, Ippia minore e Protagora
Authors: Venturelli Silvia
Published: May 2020

The analogy between virtue and crafts is the core of Socratic ethics, whose fundamental principle is that virtue is a kind of knowledge similar to technical skills. Moral knowledge, however, is on a superior level and is different from other crafts since it concerns the ends of human action. This article aims to show that the main purpose of Laches, Charmides, Lesser Hippias and Protagoras is to bring out this distinction. More specifically, all the four dialogues follow a similar pattern, i.e. they lead to the conclusion that virtue is moral knowledge by means of preliminary argumentations which consider the opposite view, supposing that it consists in technical knowledge. Thus we are shown the difficulties arising if we fail to distinguish moral knowledge, before the dialogue reaches its positive conclusion.
Anaxagorae Homoeomeria
Authors: Torrijos-Castrillejo David
Published: May 2020

Aristotle introduced in the history of the reception of Anaxagoras the term “homoiomerous”. This word refers to substances whose parts are similar to each other and to the whole. Although Aristotle’s explanations can be puzzling, the term “homoiomerous” may explain an authentic aspect of Anaxagoras’ doctrine reflected in the fragments of his work. Perhaps one should find a specific meaning for the term “homoiomerous” in Anaxagoras, somewhat different from the one present in Aristotle. This requires a review of the sense of the two terms involved in it: “homoios” and “moira”. In other words, the following questions should be answered: what realities are named parts and to what whole do they belong? On the other hand, which similarity do they have to each another and to the whole? The author concludes that the parts are “all things”, which resemble each other and the universe as a whole because, according to Anaxagoras, they are all composed of all things.
Insight on the effect of a piperonylic acid derivative on the
crystallization process, melting behavior, thermal stability, optical and mechanical
properties of poly(l-lactic acid)
Authors: Zhao Li-Sha , Cai Yan-Hua
Published: May 2020

A new piperonylic acid derivative (BPASD) was synthesized and evaluated as an organic
nucleating agent for poly(l-lactic acid) (PLLA) via melt-crystallization;
the other behaviors including cold-crystallization, melting process after
crystallization, thermal stability in air atmosphere, and optical and mechanical
properties of PLLA/BPASD samples were also investigated. The results of the
melt-crystallization investigation showed that, in comparison to virgin PLLA, the
BPASD could induce PLLA to crystallize in higher temperature region or at a faster
cooling rate, suggesting that the BPASD as a heterogeneous nucleating agent could
promote the crystallization of PLLA, but the melt-crystallization depended on the
cooling rate, BPASD concentration, and the final melting temperature. With increasing
of BPASD concentration, a shift to the lower temperature of cold-crystallization peak
and decrease of crystallization enthalpy indicated that BPASD had an inhibition for
the cold-crystallization of PLLA to some extent. The heating rate, crystallization
temperature, the BPASD, and its concentration were critical factors to the melting
process, and double-melting peaks appeared in heating were assigned to
melting–recrystallization. Thermal decomposition behavior revealed that the
addition of BPASD reduced the thermal stability of PLLA, but the interaction of PLLA
and BPASD could prevent the decrease of the onset decomposition temperature. Further,
the BPASD also decreased the light transmittance and elongation at the break of PLLA,
but the tensile modulus and tensile strength of PLLA were enhanced.
Synthesis and biological evaluation of novel 4-oxo-5-cyano thiouracil derivatives as SecA inhibitors
Authors: Bamba Fante , Jin Jinshan , Tai Phang C. , Wang Binghe
Published: May 2020

The continuous emergence of drug-resistant strains of bacteria poses an urgent risk to human health and dictates the need for new antimicrobials. Along this line, we have been working on developing inhibitors of SecA, a key component of the bacterial Sec-dependent secretion machinery. Herein, we describe the synthesis and antimicrobial evaluation of 6-oxo-1,6-dihydropyrimidine-5-carbonitrile derivatives as potential SecA inhibitors.
Lit-L1-L2: Ein Instrument zur Einschätzung literaler Kompetenzen von neu zugewanderten Jugendlichen in der L1 Dari und der L2 Deutsch
Authors: Czinglar Christine , Schumacher Anne-Christin , Mirova Farzona , Faseli Sarah
Published: May 2020

Für die Zuweisung von neu zugewanderten Jugendlichen und Erwachsenen zu Vorbereitungsklassen und Integrationskursen ist es notwendig, neben den Fähigkeiten in der Zweitsprache (L2) auch die literalen Kompetenzen in der Erstsprache (L1) miteinzubeziehen. Das Instrument Lit-L1-L2 wurde entwickelt, um basale literale Kompetenzen von Lernenden mit L1 Dari und geringen Deutschkenntnissen zu erheben, und kann von Lehrkräften ohne Kenntnisse in Dari eingesetzt werden, da es auf einer sprachübergreifenden Bewertung des Verhaltens und des Schriftbildes basiert.
The Crisis of Becoming-Nature in Howard Barker’s Recent Dramas
Authors: Gritzner Karoline
Published: May 2020

This article discusses how in Howard Barker’s recent work the idea of the subject’s crisis hinges on the introduction of an impersonal or transpersonal life force that persists beyond human agency. The article considers Barker’s metaphorical treatment of the images of land and stone and their interrelationship with the human body, where the notion of subjective crisis results from an awareness of objective forces that transcend the self. In “Immense Kiss” (2018) and “Critique of Pure Feeling” (2018), the idea of crisis, whilst still dominant, seems to lose its intermittent character of singular rupture and reveals itself as a permanent force of dissolution and reification. In these plays, the evocation of nonhuman nature in the love relationships between young men and elderly women affirms the existence of something that goes beyond the individual, which Barker approaches with a late-style poetic sensibility.
Fifteen-Minute Moments: Black Women’s Short Plays as a Political Aesthetic of Crisis
Authors: Goddard Lynette
Published: May 2020

This article examines short plays as a political aesthetic of crisis using examples from Black Lives, Black Words (2015–2017) at the Bush Theatre, London, which respond to concerns arising from the #BlackLivesMatter movement about Black deaths in police custody. I focus on Black women playwrights’ portrayals of Black mothers’ anxieties about protecting their sons, and of Black mothers and sisters grieving the loss of sons, brothers, and fathers in incidents where excessive force is deployed by the police. I consider how Black Lives, Black Words connects to the radical aesthetics of the 1960 s Black Arts Movement by promoting the use of theatre for activist purposes. I argue that the politicising potential of the Black Lives, Black Words initiative is accentuated by the use of a short play format as a political Black aesthetics for responding to contemporary crises. By analysing pivotal moments in a sample of the fifteen-minute plays, I demonstrate how the content of the plays combines with their performance styles to maximise the potential for audience empathy despite their short playing times.
High-performance fiber-shaped lithium-ion batteries
Authors: Zhang Ye
Published: May 2020

This short review summarizes our recent progress in fiber-shaped lithium-ion batteries and lithium-air batteries based on carbon nanotube hybrid fiber electrodes. The fiber architecture allows batteries to be deformable in all dimensions and bear various deformations such as bending, tying, twisting and even stretching. They are scaled up and further woven into breathable, flexible, stretchable and shape-memory textiles to effectively meet the requirements of modern electronics such as wearable products.
A hybrid air-sea cooperative approach combined with a swarm trajectory planning method
Authors: Bella Salima , Belbachir Assia , Belalem Ghalem
Published: May 2020

This work addresses the issue of ocean monitoring and clean-up of polluted zones, as well as the notion of trajectory planning and fault tolerance for semi-autonomous unmanned vehicles. A hybrid approach for unmanned aerial vehicles (UAVs) is introduced to monitor the ocean region and cooperate with swarm of unmanned surface vehicles (USVs) to clean dirty zones. The paper proposes two solutions that apply to trajectory planning from the base of life to the dirty zone for swarm USVs. The first solution is performed by a modified Genetic Algorithm (GA), and the second uses a modified Ant Algorithm (AA). The proposed solutions were both implemented in the simulation with different scenarios for the dirty zone. This approach detects and reduces the pollution level in ocean zones while taking into account the problem of fault tolerance related to unmanned cleaning vehicles.
PENGEMBANGAN PERANGKAT PERKULIAHAN KURIKULUM BERBASIS KOMPETENSI DAN KONSERVASI MELALUI LESSON STUDY UNTUK PENGUATAN LAYANAN PERKULIAHAN BAGI DOSEN MUDA DI FMIPA UNNES
Authors: Wiyanto W. , Cahyono E. , Suwarsi E. , Parmin P.
Published: May 2020

Penelitian bertujuan untuk mengetahui; kefektifan perangkat perkuliahan berbasis kompetensi dan konservasi yang dikembangkan melalui kegiatan lesson study. Penelitian menerapkan metode deskriptif kualitatif dengan menerapkan langkah-langkah lesson study. Hasil penelitian perangkat perkuliahan yang dikembangkan melalui kegiatan lesson study efektif diterapkan.The study to determine; the effective of competency based learning and conservation to developed through lesson study. Apply to descriptive method qualitative research by applying the steps of lesson study. The results of the research tools developed through the course lesson study effective applied.
PENERAPAN CRITICAL REVIEW TERHADAP BUKU GURU IPA KURIKULUM 2013 UNTUK MENGEMBANGKAN KEMAMPUAN MAHASISWA DALAM MENYUSUN PERANGKAT PEMBELAJARAN BERPENDEKATAN SAINTIFIK
Authors: Khusniati M. , Pamelasari S.D.
Published: May 2020

Penelitian bertujuan untuk mengembangkan kemampuan mahasiswa dalam menyusun perangkat pembelajaran berpendekatan saintifik. Penelitian dirancang dengan metode penelitian tindakan kelas. Berdasarkan hasil penelitian yang telah diperoleh, dapat disimpulkan penerapan critical review terhadap buku guru IPA kurikulum 2013 dapat mengembangkan kemampuan mahasiswa dalam menyusun perangkat pembelajaran berpendekatan saintifik.The research to develop students ability to formulate scientific approach learning. The study was designed with the method to action research. Based on the results that have been obtained, can be concluded the application of the critical review of the 2013 book science teacher curriculum can develop students ability to formulate scientific approach learning.
On limit theorems for random fields
Authors: Banys Rimas
Published: May 2020

A complete separable metric space of functions defined on the positive quadrant of the plane is constructed. The characteristic property of these functions is that at every point x there exist two lines intersecting at this point such that limits limy→x f (y) exist when y approaches x along any path not intersecting these lines. A criterion of compactness of subsets of this space is obtained.
Survey of VPU olympiad for young mathematicians
Authors: Jakaitytė Eglė , Mazėtis Edmundas
Published: May 2020

The article presents problems of VPU Young Mathematicians‘ Olympiad 2009, their solution and a short statistical anglysis of Lithuanian Olympiad movemenr of mathematicians.
School mathematical olympiad-2009
Authors: Mačys Juozas Juvencijus
Published: May 2020

The texts and solutions of the Lithuanian school mathematical olympiad-2009 are presented.
Review of the Kangaroo competition
Authors: Mačys Juozas Juvencijus , Sušinskas Jurgis
Published: May 2020

The results and tasks of Lithuanian Kangaroo competition-2009 are presented.
Opportunities for modelling inflation processes in Lithuania
Authors: Čuvak Ana , Kalinauskas Žilvinas
Published: May 2020

Inflation is a constant and consistent increase in the general price level in the country, due to which the purchasing power of a national currency unit decreases. In practice, the measures of inflation are various price indices, such as a consumer price index (CPI), producer price index (PPI), or gross domestic product deflator. However, inflation is usually defined as a change in the HCPI over a year. Time series models, linear regression models and a vector autoregression model (VAR) can be used to model and forecast inflation processes. This paper examines Lithuanian consumer price inflation using a modern stationary time series and econometric theory. The vector autoregression model is proposed for inflation modelling. Theoretical aspects of model estimation are reviewed: time series stationarity, model identification, parameter estimation, model usage and forecasts. The stationarity of the HCPI index and exogenous variables are analyzed using the Augmented Dickey–Fuller (ADF) test. A vector autoregression model of Lithuanian inflation processes is investigated and proposed for inflation modelling. The obtained model is used for forecasting purposes and shows a fairly high degree of accuracy of the  inflation forecast in the coming 12-month period.
Specialization of antecedent negation loop-rule for a fragment of propositional intuitionistic logic sequent calculus
Authors: Alonderis Romas
Published: May 2020

The paper deals with specialization of the antecedent negation loop-rule for the negative implication free fragment of the propositional intuitionistic logic.
Investigation of the barrier options pricing models
Authors: Palivonaitė Rita , Valakevičius Eimutis
Published: May 2020

In the article three methods of barrier option pricing are analysed and compared: Black–Scholes, trinomial ant adaptive mesh algorithm. Investigation with Lithuanian firm’s stock showed, that to get better results it is offered to adapt higer resolution mesh on critical regions of trinomial tree.
Simulation study of a tree similarity measure based on small subtree counts
Authors: Bloznelis Mindaugas , Radavičius Irmantas
Published: May 2020

Augsten, Böhlen and Gamper [1] suggested a measure of similarity between ordered and labeled trees based on subtree counts: two trees are declared close if they contain similar number of copies of ordered and labeled subtrees of a given form, called pq-gram. We report the results of a simulation study of statistical properties of distances based on pq-grams.
Analysis and evaluation of ADBMS rules activity
Authors: Laučius Juozas , Ribikauskas Arūnas , Trinkūnas Justas
Published: May 2020

Article presents analysis and evaluationof ECA rules activity.Most of active rules are implemented by triggers and functions. Sophisticated rules based systems have several problems including difficulty to control and analyse the system. We propose to use Functional Size Measurement Method to evaluate activity of rules in ADBMS. A function point is a unit of measurement to express the amount of businessfunctionality an information system provides to a user. Paper provides major reasons and benefits for using this method.
Convolutions of generalized measures
Authors: Padvelskis Kazimieras , Bikelis Algimantas
Published: May 2020

The convolutions of probability distributions of independent random variables are analysed in this paper.
The Representation of Kiai Ahmad Arrifai Kalisalak in Repen Ripangi
Authors: Islam M. Adib Misbachul , Oktafiyani Elve
Published: May 2020

This study aims to discuss the meaning of Repen Ripangi as a literary narrative manuscript of Adipati Panji Suryakusuma, Regent of Semarang which was then composed in the form of macapat song by Panji Jayasubrata. By placing it in the context of social and political history in Java in the nineteenth century, the text reveals the tension between the two social elites during the colonial period in a form of narrative poetry. This research used qualitative method with representation theory. The results show that the writing of Repen Ripangi in the form of narrative poetry was not merely an aesthetic expression of the author Javanese priayi, but also a means of representation which goal is the stigmatization of Kiai Ahmad Arrifai as a kiai who brings apprehension in society. In addition, another goal of the representation in Repen Ripangi was to strengthen of the penghulu as one of religious authorities in Java during the colonial period and the defense of priyai interests and their political patrons, namely the colonial government in Java.
A formação inicial em Licenciatura em Educação Especial na perspectiva dos egressos
Authors: Lustosa Ana Valéria Marques Fortes , Mendes Enicéia Gonçalves
Published: May 2020

A formação inicial do professor se configura como um dos momentos mais relevantes do desenvolvimento profissional, e se torna inquietante o esvaziamento e a desqualificação que essa etapa da profissionalização docente tem sofrido nos últimos tempos em virtude das disposições neoliberais. No campo da Educação Especial, a situação se agrava ainda mais dada a escassez de cursos de formação inicial, associada a uma política de formação continuada e na modalidade a distância. O presente estudo de natureza qualitativa do tipo exploratório, visou investigar a importância da formação inicial em Educação Especial, na perspectiva de egressos. Os resultados indicam que a formação inicial específica na área parece favorecer a construção da identidade e a profissionalização desde o momento em que os jovens entram na universidade, sendo que isso se fortalece na medida em que eles avançam no curso. Além disso, o curso parece favorecer atitudes positivas em relação à inclusão e a diminuição de preconceitos.
Ser criança indígena terena no espaço da cidade: cultura, escola e brincadeira
Authors: Naglis Vieira Carlos Magno , Casaro Nascimento Adir
Published: May 2020

Com o objetivo de apresentar as crianças indígenas Terena de duas aldeias indígenas urbanas da cidade de Campo Grande/MS, mostrando os lugares por onde circulam, as culturas que produzem e ressignificam, as brincadeiras que realizam, os conflitos e as tensões no espaço urbano (aldeias urbanas e escola), o artigo que parte das experiências de pesquisas dos autores, elabora reflexões em uma temática que ainda desperta pouco interesse, apesar de nos últimos anos se verificar um crescimento tímido sobre produções desse outro espaço de vivência de criança indígenas. Nesse sentido, o estudo que está marcado pelo pensamento de autores que se situam na convergência entre os estudos da Antropologia da Criança, das teorias pós-coloniais e dos estudos de Cultura, pretende criar visibilidade para futuros debates envolvendo uma temática, ainda vista como marginalizada, subordinada e silenciada no espaço da academia.
A complementaridade de pais e de profissionais na avaliação em Intervenção Precoce
Authors: Pereira Ana Paula Da Silva , Jurdi Andréa Perosa Saigh , Silva Reis Helena Isabel
Published: May 2020

O estudo teve por objetivo analisar a convergência entre pais e profissionais relativamente à avaliação da área da interação social em crianças com TEA, entre 3 e 6 anos, apoiadas pelo sistema de intervenção precoce em Portugal. A metodologia é de natureza quantitativa correlacional e a amostra foi constituída por 128 crianças com TEA. Os resultados concluem que os pais avaliam mais positivamente, a dimensão da interação social, comparativamente com os profissionais; a variável idade influenciou a avaliação de pais e de profissionais, verificando-se uma relação positiva entre as competências e o avanço da idade das crianças; as variáveis formação inicial, anos de experiência dos profissionais no apoio a crianças com TEA, nível educacional e profissional dos pais não influenciaram os resultados ao nível da interação social. A investigação sugere a importância da intervenção precoce, priorizando as relações de colaboração entre pais e profissionais no processo de avaliação.
Bebês com deficiência no Brasil: um olhar a partir dos programas governamentais e pesquisas nacionais
Authors: Rozek Marlene , Martins Gabriela Dal Forno
Published: May 2020

Este estudo objetivou mapear programas governamentais e a produção científica brasileira sobre as políticas públicas de inclusão nos três primeiros anos de vida. O levantamento dos programas ocorreu através dos sites dos Ministérios da Educação, Saúde e Desenvolvimento Social, já da produção científica através de uma revisão de teses, dissertações e artigos. Conclui-se que tanto os programas quanto a literatura direcionam pouca atenção específica à criança de zero a três anos com deficiência. A Assistência Social mostrou-se como o setor que mais tem investido na proposição de programas para este público, já a Educação aquele que mais tem publicado estudos no campo, predominantemente sobre políticas de inclusão escolar. Ressalta-se a urgência da proposição e avaliação de políticas públicas intersetoriais para essa população, que visem a inclusão de forma mais abrangente, proporcionando bases favoráveis para o desenvolvimento do bebê e da criança pequena.
La Competencia Emocional en Atención Temprana: Perspectiva de padres y profesionales
Authors: Escorcia Claudia Tatiana , Díaz Martínez Pedro Enrique
Published: May 2020

Se considera que educar en emociones es una tarea fundamental, que deben asumir los padres y profesionales, ya que el desarrollo de su competencia, permite mejorar otros aspectos de su vida. En los últimos años, la investigación en el campo de las emociones ha aumentado, sin embargo, en el área de intervención temprana y educación especial hay pocos estudios específicos. Esta investigación, realizada a través de grupos focales, busca identificar la importancia que tanto los padres como los profesionales le dan a las competencias emocionales y sus implicaciones para el desarrollo del niño. Los resultados sugieren que los profesionales y padres creen manejar los aspectos emocionales, sin embargo, su manejo es sólo en algunas categorías y de forma empírica, basándose en su experiencia personal. Queda clara la necesidad de formación en el tema y la realización de un seguimiento del estado emocional de niños, padres y profesionales.***A Competência Emocional em Intervenção Precoce: Perspectivas dos pais e dos profissionais***Considera-se que educar as emoções é uma tarefa fundamental que deve ser assumida por pais e profissionais, pois o desenvolvimento de sua competência permite aprimorar outros aspectos de sua vida. Nos últimos anos, as investigações neste campo aumentaram, contudo, existem poucos estudos específicos na área de intervenção precoce e educação especial. Esta pesquisa, realizada por meio de grupos focais, procura identificar a importância que os pais e profissionais atribuem às competências emocionais e suas implicações no desenvolvimento da criança. Os resultados sugerem que os profissionais e os pais acreditam que gerem os aspectos emocionais; no entanto, a sua gestão é apenas em algumas categorias e de forma empírica, com base na sua experiência pessoal. Ficou clara a necessidade de formação neste assunto e a monitorização do estado emocional de crianças, pais e profissionais em futuros estudos.Palavras chave: Atenção precoce, práticas centradas na família, habilidades emocionais, educação emocional.
Intervenção Precoce na Infância centrada na família: práticas e pesquisa
Authors: Rozek Marlene , Serrano Ana Maria
Published: May 2020

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Programa Nacional do Livro Didático de Física: subsídios para pesquisas
Authors: Schivani Milton , Souza Gustavo Fontoura de , Lira Natália
Published: May 2020

Resumo O livro didático de Física continua sendo um dos principais recursos utilizados na Educação Básica Pública Brasileira, sendo objeto de estudo de diversas pesquisas. Contudo, considerações sobre a abrangência nacional dos livros selecionados para análise não estão presentes em muitas dessas pesquisas, podendo dificultar ou impedir uma melhor interpretação dos resultados obtidos e definição dos critérios de escolha das obras para análise. Assim, objetivando fornecer subsídios para apoiar pesquisas sobre livro didático de Física do Ensino Médio, efetuamos um levantamento do total de coleções adotadas em todo o território brasileiro para o triênio 2018-2020. Os dados foram obtidos junto ao Fundo Nacional de Desenvolvimento da Educação (FNDE), correspondem às escolhas efetuadas pelas escolas públicas ao final do ano de 2017. Em linhas gerais, observou-se uma significativa uniformidade nacional, especialmente nas regiões sudeste e nordeste. Uma coleção, reconhecida como de perfil mais tradicional, destacou-se como sendo aquela com maior número de livros adotados em 21 (vinte e um) estados.
Desenvolvimento de uma abordagem teórica do conceito de ondas térmicas para compreensão da variação de temperatura em filmes finos e sólidos
Authors: Couto Flávio M. do , Carvalho Ramon D. , Faria Júnior Roberto T. , Macedo Francisco J. M. de
Published: May 2020

Resumo O presente trabalho estabelece uma análise acerca dos conceitos de ondas eletromagnéticas e sua aplicação no processo de difusão de calor em sólidos com o propósito de compreender e difundir o conceito de ondas térmicas, tão pouco abordado dentro da academia. Com essa análise é possível identificar como a temperatura varia em função das propriedades termofísicas dos materiais quando uma amostra é submetida a uma excitação modulada e periódica por meio de ondas eletromagnéticas. Isso permite a utilização de técnicas fototérmicas, por exemplo, radiometria fototérmica, para determinar as propriedades térmicas de materiais como filmes finos e sólidos homogêneos. O conteúdo aqui desenvolvido pode ser amplamente abordado sob a forma de disciplinas em cursos de graduação e pós-graduação para alunos de física, engenharias e áreas afins.
Measurement of Long Bones of Southern Minas Gerais, Brazil: Anthropometric Study
Authors: Alessandra Esteves  , Wagner Costa Rossi Junior  , Wagner Corsini  , Flávia Da Ré Guerra  , Petrus Pires Marques  , Luis Henrique Rapucci Moraes  , Denismar Alves Nogueira  , Isabela Ferreira Corrêa
Published: May 2020

This study aims to estimate the main measures in long bones of Southern Brazilians adults, and to compare them with those of other ethnicities already cataloged in literature. The measurements were made with an anthropometric ruler and a digital caliper, according to a specific protocol. For this, being the humerus, radius, ulna, femur and tibia (50 specimes of each bone) in which some parameters were measured that allow comparing with existing data in literature. The data shown the mean (cm) and the standard deviation of long bone measured. Femurs are: ML = 46.41 ± 2.35, EW = 7.84 ± 0.57 and HD = 4.43 ± 0.47; Humerus: ML = 33.52 ± 1.45, EW = 6.04 ± 0.39, HD = 4.48 ± 0.24; radios: ML = 26.24 ± 1.51 and APD = 1.58 ± 0.14; ulna: ML = 27.9 ± 1.41 and APD = 1.67 ± 0.10; and tibias: ML = 38.76 ± 2.21, DEW = 5.03 ± 0.38 and DAP = 4.99 ± 0.38. According to results obtained in this study, it is possible to conclude that the values used by forensic anthropology for identification of Southern Brazilian long bones, such as humerus, radius, ulna and tibia, with exception of femurs, do not in fact represent any values already established for some ethnic groups, since the Brazilians presented their own pattern, which was different from the European standard already classified.
Forensic entomology research and application in southern Africa: A scoping review (with corrigendum)
Authors: Tembe Danisile , Mukaratirwa Samson
Published: May 2020

The use of forensic entomology is well established in the northern hemisphere, but is still emerging in the southern hemisphere, where most of the current research is not explicitly undertaken in the context of forensics. In this review, we provide an update on the current status of forensic entomology research and its application in relation to estimation of post-mortem interval in various criminal investigations ranging from murder cases, cases of human neglect and the poaching of wildlife in southern Africa, among other issues. A literature search was conducted using Google Scholar, PubMed, Scopus and EBSCOhost databases. The studies reviewed were focused on arthropod diversity during different stages of carcass decomposition, effect of seasons on the abundance and diversity of carrion feeding arthropod species during carcass decomposition, and diurnal and nocturnal oviposition of forensically important insect species during carcass decomposition. It was further observed that arthropod species that established on a decomposing carcass are potentially useful in the estimation of post-mortem interval and determining clues in cases of criminal investigations. The review confirmed the paucity of research in forensic entomology, and its application in southern Africa. Future studies on the research and application of forensic entomology in various criminal investigation scenarios – such as murder cases, human neglect, and wildlife poaching in southern Africa – are therefore needed. Significance: Forensic entomology research and its application is lagging in southern Africa. There is seasonal variation in the arthropod species used for estimation of post-mortem intervals in southern Africa. Identification of arthropod species diversity in the region has potential for application in forensic investigations.