bluuebunny/crossref_metadata_2025 huggingface dataset:
VIRTUALISASI PEMBELAJARAN MENULIS DONGENG BERBASIS PRODUK ANYFLIP MELALUI SPADA KAMPUS MERDEKA
Authors: Rohmawati Ari , Oktasari Anisa Fajriana , Yulianto Bambang , Tjahjono Tengsoe , Shodiq Syamsul
Published: July 2023

Pembelajaran menulis dongeng secara daring memiliki keterbatasan dan tantangan. Dosen harus menyelenggarakan pembelajaran yang kreatif dan inovatif untuk memberikan stimulus kepada mahasiswa sehingga dapat mengikuti perkuliahan secara optimal. Stimulus yang diberikan adalah dengan anyflip dan platform SPADA Kampus Merdeka. Tujuan penelitian ini adalah untuk mendeskripsikan virtualisasi pembelajaran menulis dongeng berbasis produk anyflip melalui SPADA Kampus Merdeka. Metode penelitian yang digunakan adalah kualitatif. Teknik pengumpulan data menggunakan observasi dan wawancara. Wawancara dilakukan terhadap empat orang yaitu satu dosen pengampu mata kuliah Apresiasi Sastra Indonesia, satu mahasiswa peserta mata kuliah Apresiasi Sastra Indonesia, rekan sejawat di bidang media. Hasil penelitian menjelaskan bahwa pembelajaran menulis dongeng dilakukan secara daring. Platform yang dipilih adalah SPADA Kampus Merdeka. Adapun beberapa tahap yang harus dilalui pada pembelajaran menulis antara lain tahap prapenulisan, tahap penulisan, dan tahap pascapenulisan. Produk dari perkuliahan ini adalah sebuah buku kumpulan fabel berbasis anyflip.
KURIKULUM MERDEKA DAN PENGAJARAN BAHASA INGGRIS DI SEKOLAH DASAR: NEED ANSALISIS STUDY
Authors: Oktavia Diana , Habibah Nur , Balti Levandra , Kurniawan Ridho
Published: July 2023

Kurikulum merdeka sudah mulai diterapkan di satuan pendidikan, termasuk satuan pendidikan Sekolah Dasar. Salah satu hal penting yang digaris bawahi pada penerapan kurikulum merdeka di SD yaitu pengajaran Bahasa Inggris di SD. Penelitian ini bertujuan untuk menginvestigasi kebutuhan sekolah dalam penerapan pegajaran Bahasa Inggris di sekolah dasar yang mengacu pada kurikulum merdeka. Penelitian ini merupakan penelitian kualitatif yang dilaksanakan dengan cara interview dan penyebaran angket open-ended question. Guna mencapai tujuan, penelitian ini melibatkan delapan orang sebagai narasumber data. Para narasumber terdiri dari kepala sekolah dan beberapa orang guru dari beberapa sekolah. Berdasarkan hasil dari interview dan angket open-ended question yang telah dijawab oleh para narasumber, diketahui bahwa sekolah sangat antusias dan memliki motivasi yang sangat tinggi terhadap penerapan pengajaran Bahasa Inggris di SD. Akan tetapi, sekolah membutuhkan beberapa hal penting supaya dapat melaksanakan pengajaran Bahasa Inggris dengan efektif, seperti kebutuhan akan guru Bahasa Inggris di SD, kebutuhan pelatihan Bahasa Inggris bagi guru-guru SD, serta pemenuhan fasilitas yang dapat mendukung kegiatan pengajaran, terutama media ajar dan media pembelajaran Bahasa Inggris.
El libro como proyecto autobiográfico: ediciones de Fortunato Depero
Authors: Mancebo-Roca Juan A.
Published: July 2023

Depero futurista 1913-1927 y Fortunato Depero nelle opere e nella vita fueron proyectos editoriales esenciales en la trayectoria de Fortunato Depero ya que resumían su proceso creativo y establecían un balance biográfico. El artista consideraba que el libro cumplía una misión esencial para lograr el reconocimiento de sus creaciones en vida. Este artículo analiza las ediciones de libros y otras publicaciones de Depero desde el prevanguardismo, la seducción e irrupción futurista, la influencia de otros movimientos artísticos, su desapego y alejamiento de la vanguardia y la valoración de su trayectoria en la que apuntaba a su reconocimiento como uno de los maestros italianos del siglo XX. El artículo concluye que sus proyectos editoriales respondieron a periodos creativos trascendentes que se extrapolaron a su obra por influencia de otros agentes. Los libros y ediciones que proyectó sirven para establecer su perfil biográfico en relación con su contexto histórico y fueron determinantes en la recapitulación y proyección de su legado artístico.
La representación en el cine español de la IA asociada a la robótica: Eva y Autómata
Authors: Vidal-Mestre Montserrat , Freire-Sánchez Alfonso , López-González Jesús
Published: July 2023

Inteligencia artificial, ChatGTP y OpenAI son algunos de los términos más buscados en Google en la actualidad según Google Trends (2023). Sin embargo, parte de la concepción de la inteligencia artificial y, sobre todo, de sus posibles aplicaciones tecnológicas en la robótica avanzada, derivan de imaginarios sociales y culturales que se han construido gracias a su representación en la literatura, el cine, las series y los videojuegos. Concretamente, en el cine, películas como Blade Runner (Scott, 1984), Terminator (Cameron, 1984), AI: Artificial Intelligence (Spielberg, 2001), I, Robot (Proyas, 2004) o Ex-Machina (Garland, 2014) han proyectado la imagen de robots inteligentes como amenaza o alteridad al ser humano. El objetivo de este manuscrito es comparar el discurso de las películas españolas Eva (Maíllo, 2011) y Autómata (Ibáñez, 2014) frente al discurso científico de las 20 películas más valoradas según IMDB que incluyen la temática de inteligencia artificial. Para ello, se han triangulado tres perspectivas: el mito de Prometeo (Nieto, 2022), los principios de mitología robótica (Pérez, 2004) y la dicotomía humano - no humano (Gastaka e Iturregi, 2022), lo que ha permitido, siguiendo la metodología de Novoa et al. (2019), extrapolar las características y rasgos que definen el discurso científico de la IA en la cinematografía para poder analizar así el discurso de ambas películas españolas. Los resultados permiten concluir que no existen discrepancias entre la ciencia ficción nacional y la internacional respecto al posicionamiento de la IA como el fin de la humanidad y el diseño de sociedades distópicas y apocalípticas, aunque, particularmente, Eva y Autómata ponen a debate temas éticos y antropológicos desde diferentes prismas acerca de la ética en la robótica y la alteridad, lo que permite avivar el debate sobre la capacidad de sentir de robots y androides frente al imaginario colectivo.
Foucauldian Analysis of the Influence of Gendered Clichés on Young Learners: A Case Study
Authors: Kauser Ambreen , Khanam Aqdas , Ullah Anayat
Published: July 2023

This research work is aimed at studying how frequently gendered language is used; how far its usage is recognized, and how far the speakers perceive their ideologies to be influenced by the usage of such language in the sampled population in Chiniot and Faisalabad. This research work extracts its theoretical framework from Michele Foucault’s concept of regulatory power exercised through language (1974), and applies it to gendered language used in Pakistani society. It tries to investigate how gender biased clichés commonly used in Urdu promote and perpetuate women presence as greedy, silly, sentimental and emotional beings. A thirty item questionnaire has been administered to sampled population of 40 students. The data has been analyzed with the help of SPSS (Version 17) by using descriptive statistics. To find how common the statements are, how far are they understood by the users to be gender biased, or can the users find out or quantify the influence of such statements on their minds; frequencies, mean values and sums of responses have been calculated. The results reveal that usage of such statements is quite frequent, and the users also realize that the statements are gendered. However, the results for the third question: how far they think that their ideology is being influenced by such gendered statements, are surprising. A great number of students believe that they are not influenced by such statements, then the question arises how such statements can be so prevalent in any society, if they are not well accepted. The research implies that this area of discourse analysis needs to be properly explored, such statements should be pointed out, and their compromising impacts on thinking process of masses, particularly of young learners, must be studied.
Upaya Meningkatkan Kinerja Dan Kompetensi Pedagogik Guru Dalam Mengajar Menggunakan Media Pembelajaran
Authors: Jujur I Wayan
Published: July 2023

Penelitian ini merupakan penelitian deskriptif kuantitatif. Teknik pengumpulan data yang digunakan adalah observasi. Penelitian ini bertujuan mengetahui kinerja dan kompetensi pedagogik guru yang terdiri dari sepuluh sub kompetensi di SD No. 1 Blahkiuh, SD No. 2 Blahkiuh dan SD No. 3 Blahkiuh. Instrumen yang digunakan dalam penelitian ini berupa skala 5, terdiri atas 37 butir pernyataan. Subjek penelitian yang digunakan berjumlah 14 guru. Kinerja dan kompetensi pedagogik guru dalam mengajar menggunakan media pembelajaran di SD No. 1 Blahkiuh, SD No. 2 Blahkiuh dan SD No. 3 Blahkiuh pada awalnya tercapai nilai rata-rata sebesar 73,40 (kategori Cukup (C)) meningkat pada siklus I rata-ratanya menjadi 87,18 (kategori Baik (B)) sedangkan pada siklus II meningkat lagi rata-ratanya menjadi 92,97 (kategori Amat Baik (A)). Dari hasil yang diperoleh kinerja dan kompetensi pedagogik guru SD No. 1 Blahkiuh, SD No. 2 Blahkiuh dan SD No. 3 Blahkiuh dalam mengajar menggunakan media pembelajaran dapat ditingkatkan pada semester I tahun pelajaran 2020/2021.
Pengembangan Penerapan Marketing Digital Untuk Potensi Lokal (UMKM) di Kampung Cibadak
Authors: Adnan Iis Zilfah , Rahma Ismi Hidayatur
Published: July 2023

AbstrakKegiatan UMKM ini memproduksi makanan ber skala kecil untuk diperjual belikan dan bisa membantu perekonomian keluarga dengan mempertimbangkan potensi local yang ada pada masyarakat baik itu dari jasa dan juga bahan-bahan untuk diproduksi.Â  Potensi local pada masyarakat Kp. Cibadak di Desa Leuwigoong dengan situasi lahan yang kering dan hanya beberapa pertanian yang cukup kuat diantaranya pohon singkong, dengan pohon singkong ini dimafaatkan oleh masyarakat untuk dijadikan usaha kecil. Tujuan dari pengabdian masyarakat ini merupakan mengembangkan potensi masyarakat setempat dengan melihat keadaan di daerah tersebut, seperti di Kp. Cibadak ini dengan lahan yang kering dan pohon singkong yang berlimpah sehingga dimanfaatkan oleh masyarakat untuk dijadikan suatu produk yaitu dengan memproduksi Kicimpring dengan bahan utama 90% singkong dan sisanya merupakan rempah untuk memperkuat cita rasa dari kicimpring. Metode yang digunakan adalahÂ  pengetahuan melalui seminar pada masyarakat dan berkoordinasi dengan pelaku atau mitra UMKM dan narasumber dari perguruan tinggi untuk pengembangan suatu produk dalam pemasaran kicimpring pada masyarakat. Hasil dari pengabdian masyarakatÂ  melalui program besama dengan masyarakat ini untuk membantu UMKM di Kp. Cibadak baik itu dari system pemasaran, dan inovasi baru dan melalui seminar ini masyarakat bisa berkreasi untuk menyesuaikan dan bersaing dengan pasar.Â  Keyword : UMKM, Digital marketing, Kp. Cibadak Â AbstrakThese community businesses or MSME activities produce small-scale food to be traded and can help the family economy by considering the local potential that exists in the community, both from services and materials to be produced. Local potential in the Kp community. Cibadak in Leuwigoong Village with a dry land situation and only a few strong enough agriculture including cassava trees, with this cassava tree used by the community to be used as small businesses. The purpose of this community service is to develop the potential of the local community by looking at the conditions in the area, such as in Kp. This Cibadak, with dry land and abundant cassava trees, is used by the community to be used as a product, namely by producing Kicimpring with 90% cassava as the main ingredient and the rest is spices to strengthen the taste of Kicimpring. The method used is knowledge through seminars in the community and coordinating with MSME actors or partners and resource persons from universities for the development of a product in marketing kicimpring to the community. The results of community service through this joint program with the community to help MSMEs in Kp. Cibadak is good from the marketing system, and new innovations and through this seminar the community can be creative to adapt and compete with the market. Keyword : UMKM, Digital marketing, Kp. CibadakÂ
Distorção idade-série e evasão no ensino médio regular diurno na E.E.E.F.M. Prof. José Gonçalves de Queiroz entre os anos de 2010 a 2016.
Authors:   , Maria Pereira Maciel Kátia
Published: July 2023

O presente trabalhou buscou analisar os alunos do Ensino Médio regular do turno diurno da E.E.E.F.M. Professor José Gonçalves de Queiroz que se encontram em situação de distorção idade-série para identificar os motivos que os levaram a atrasar o seu fluxo escolar e a taxa de abandono destes durante os anos de 2010 a 2016. Para isto foi utilizado os Resultados Finais dos anos em questão arquivados na escola, que mostraram que o número de matrículas de alunos nesta situação aumentou a cada ano, principalmente no 1º ano do Ensino Médio e que o maior número de desistência também acontece nesta etapa, sendo quase inexistente no 3º ano desta fase da educação básica. Posteriormente houve a aplicação de questionários com os alunos em distorção idade-série que estão matriculados no turno diurno no ano letivo de 2017 e que ainda estão frequentando regularmente as aulas para investigar quais motivos os levaram a atrasar o seu fluxo escolar. Através dos resultados obtidos pelos questionários foi possível concluir que o que levaram estes alunos a estarem em defasagem com relação a idade e série que estão matriculados foram as consequentes repetências e que estas foram ocasionadas pelo desinteresse deles pelo estudo.
Cultura organizacional e instituições públicas: um panorama sobre os estudos publicados entre 2007 a 2017 no Brasil.
Authors:   , Michel de Sousa Santos Isleno
Published: July 2023

A formação do povo brasileiro compõe-se por diferentes características culturais e por diversos povos. Essas diferentes características culturais levaram às organizações públicas no Brasil a vivenciarem diversas transformações. O objetivo geral dessa pesquisa é investigar a produção científica sobre cultura organizacional brasileira no âmbito público na última década (2007-2017), assim como também conceituar e compreender o conceito de cultura organizacional, a partir de um levantamento das pesquisas no contexto brasileiro durante o tema e período supracitado. Trata-se, portanto, de uma revisão sistemática da literatura, de natureza exploratória e descritiva de cunho quali-quantitativo, a partir de consultas aos portais da Associação Nacional de Pós-Graduação e Pesquisa em Administração, a Revista Brasileira de Administração Científica, a Revista Brasileira de Administração Pública e ainda a base de dados da Scielo. Como resultados da pesquisa, destaca-se a baixa produção da temática nos últimos dez anos (2007 a 2017). No que se refere à produção por região, percebe-se uma centralidade de pesquisas e estudos publicados na região sudeste, mais notadamente na cidade do Rio de Janeiro, seguido por São Paulo. Desse modo, observa-se que a temática ainda carece de estudos e aprofundamento nas análises, apesar de encontradas pesquisas realizadas em nível municipal, federal e estadual, com a utilização de variadas metodologias nestes estudos.
Peran Otoritas Jasa Keuangan Terhadap Pencegahan Transaksi Keuangan Mencurigakan Pada Sektor Perbankan Ditinjau Dari Undang-Undang Nomor 21 Tahun 2011 Tentang Otoritas Jasa Keuangan
Authors: Yulianti Yulianti
Published: July 2023

This study aims to examine the role of the financial services authority in the prevention of suspicious financial transactions in the banking sector, examine the obstacles faced by OJK in supervising the prevention of suspicious financial transactions in the banking sector and the efforts made by the Financial Services Authority to prevent suspicious financial transactions in the banking sector.

This research uses the Normative-Empirical Legal Research Method, namely the legal research method which is basically a combination of normative legal approaches with the addition of various empirical elements.

The role of the Financial Services Authority in preventing suspicious financial transactions is to conduct Offsite Supervision, Onsite Supervision, and Risk Level Assessment of TPPU and TPPT, The obstacle faced by the Financial Services Authority in Supervising suspicious financial transactions is the still weak CHD infrastructure in implementing the AML CFT program to identify suspicious transactions. while the Financial Services Authority's efforts to prevent suspicious financial transactions are that it has issued several provisions governing CHDs in the implementation of the AML CFT program
How New Regulations of Micro Finance Sector Transform the Old Ones and Its Impact
Authors: Pravallika Pragallapati J L , Teki Prof S. , Bhaskar N. Udaya
Published: July 2023

Old and new regulations in the microfinance industry in India are compared in this paper. For providing financial services to small businesses and low-income individuals, the microfinance sector plays a significant role. Over time, for ensuring consumer protection and addressing the emerging challenges appropriately the regulatory framework governing the microfinance industry has evolved. Including broader applicability for various regulated entities, introducing new regulations has brought about significant changes. The aim of conducting this research is to analyze the transformations in regulations along with their impact on the microfinance industry. The paper initiated an introduction to the microfinance industry and its importance in India. The requirements for the regulatory reforms are highlighted within the problem statement section, while the study objectives are outlined clearly in the research purpose section. The significance of understanding the regulatory change’s impact on industry functioning is emphasized within the relevance and significance section. To guide the study effectively there are three research questions well formulated in this paper. The barriers and issues associated with the old regulations are discussed during the study and for providing a comprehensive understanding of the subject, the literature review is conducted. The approach used for the collection and analysis of data is clearly outlined within the methodology section. The empirical data is provided within the research findings, analysis, and results section. The valuable insights into the impact of new regulations are provided clearly within this section. The key findings and recommendations for policymakers are summarized in the conclusion section.
Analysis of the intestinal microbiota and its relationship with neuropathologies
Authors: Menezes Carlos Alexandre Gomes Passarinho , Benedito Rafaela Ribeiro , Facundo Daniel Rubens Freitas , Moura Isabela Oliveira , Lima Patrick Venâncio Soares , Melo Amandra Gabriele Coelho Rodrigues , Pimenta Bruna Gontijo Peixoto , Mitani Anna Luiza Staianov , Santos Larissa Oliveira dos , Rodrigues Lais Pioli Righeti , Saber Ana Julia Gancedo , Ferreira Rosana
Published: July 2023

Introduction: The human intestinal microbiota corresponds to the ecosystem of colonizing microorganisms of the intestine that has an important role of protection to the organism. In addition, it has a direct relationship with the nervous system, known as the bowel-brain axis. Changes in the intestinal microbiota have been associated with several neuropathologies, and disbiosis repair has been shown to improve specific symptoms of some diseases. Objectives: This study aims to analyze the neurological implications caused by intestinal microbiota in humans. Methods: Review of integrative literature, consulted the Databases PubMed, SciELO and Google Academic. Chosen as descriptors (DeCS): “Microbiota”, “Gastrointestinal Microbiome” and “Nervous System Diseases” separated by Boolean connectors, and articles in English and Portuguese. Results: In this sense, among the therapeutic techniques that objectify to recolonize the “‘sick” intestine, the use of probiotics and fecal microbiota transplantation stand out. Symbiotics, a combination of probiotics and prebiotics, proved beneficial for symptomatological manifestations of neuropsychic disorders such as depression and chronic stress. Conclusion: Although some of the relationships of the intestinal-brain microbiota axis and changes in the intestinal microbiota, as well as the pathophysiology and benefits arising from its health, there is still a lack of studies to make consensus whether a change in the intestinal microbiome would be an epiphenomenon or the cause of neuropathologies in humans.
The epidemiology of accidental tetanus in Brazil
Authors: Ribeiro Fernanda Cristina Poscai , Santos Victória Lobato , Nascimento Vitor da Nóbrega , Oliveira Camille Cipriano Vanini Tupinambá de
Published: July 2023

Introduction: Tetanus is an acute intoxication caused by tetanospasmin, which binds irreversibly to spinal cord and brainstem receptors, being taken there through retrograde axonal transport, blocking inhibitory neurotransmission, promoting muscle contraction, spasms and a hypersympathetic state. Methods: The work is a descriptive study that statistically analyzes and describes the cases of accidental tetanus in Brazil between 2012 and 2022 through data obtained by the Information System of Notifiable Diseases (SINAN). Results: The total number of cases was 2.596 and 846 progressed to death. The annual media was 236 cases. From 2012 to 2022, the percentage change in the number of annual new cases was -38.55%, demonstrating a drop in the number of cases. Also, the percentage change in the lethality from 2012 to 2022 was -76.53%. Among the regions, Northeast had the highest prevence (31.9%). Regarding skin color/ethnicity is: White: 32.51%; Black: 8.35%; Brown: 52.54%. The most affected age group was 40–59 years old (n% = 39.21). Of the 846 reported deaths, 313/846 occurred in this age group. About sex, 2212 cases ocurred in men. Data on the education show that 129 were illiterate; 29.9% have an incomplete secondary education; 8.16% have completed secondary education; Ignored/blank: 47.45%. Conclusion: Despite the reduction in cases, a reflection of greater vaccination coverage, tetanus still has a high lethality. The increase in cases with aging, but still in working age can be explained by the reduction of reflexes, ability and visual acuity. The pattern of higher prevalence in men can be elucidate by the work distribution, in which they are the majority in professions with higher risk, such as agriculture and construction. Furthermore, there is a pattern of low education linked to a greater number of cases, which can be explained by the work pattern and low adherence to vaccination campaigns in these groups.
Pharyngeal-cervical-brachial variant of Guillain-Barre syndrome overlap with Bickerstaff brainstem encephalitis
Authors: Rezende Renata Gratão , Souza Isadhora Maria Maran de , Tiago Rodrigo Ibañez , Florêncio Isabela Carvalho , Azambuja Igor , Fernandes Thiago Dias
Published: July 2023

Guillain-Barré Syndrome (GBS) is a rare disease. Its classic presentation is an acute tetraparesis and absence or diminished tendon reflex. Clinical variants such as Pharyngeal-cervical-brachial (PCB) and Bickerstaff brainstem encephalitis (BBE) can occur. We report a case of PCB and BBE overlap, with electrophysiological pattern of acute motor sensory axonal neuropathy. A 36-year-old man with recent dengue virus infection, was evaluated in the emergency department, complaining of double vision and eyelid drop for one week. Neurological examination showed palpebral ptosis, dysarthria, cervical and upper limb weakness, dysphagia, and diplopia with absent deep tendon reflexes in the upper limbs. The cerebrospinal fluid analysis as well as head computed tomography were unremarkable. Electroneuromyography demonstrated axonal sensory-motor polyneuropathy. The patient was treated with Human immunoglobulin, plasmapheresis and ventilation support. There was gradual improvement after treatment, with complete recovery after 6 months. About 60% of GBS cases experienced previous infection preceding neurological manifestations in up to 8 weeks. Although rare, dengue virus is a well-known possible trigger of GBS. Variants may overlap due to the existence of a crossed response against the glycoside GQ1b, related to PCB e BBE, expressed in peripheral nerves, spinal cord, cranial nerves, and brainstem, which probably occurred in the reported case. It is important to recognize isolated or superimposed clinical variants of GBS and its differential diagnosis.
Atypical presentation of Stiff Person syndrome: case report
Authors: Domingos Francine de Paula Roberto , Hirayama Sayuri Aparecida , Almeida Rafael de , Dias Lucas Silva , Oliveira Paulo Henrique Martinelli , Santos Raderi Luiz Cardoso dos , Miyashiro Larissa , Araújo Lorena Dias de , Costa Gustavo Carvalho
Published: July 2023

Introduction: Stiff Person syndrome (SPS) is a rare, immune-mediated neurological disease related to several antibodies, the most obvious being Antiglutamic acid decarboxilase (GAD). This case intends to show atypical clinical presentation of Stiff Person Syndrome, in which the patient started with ataxia and gait alteration, evolving with dimidiated spasms. Case report: L.S.M, male, 58 years old, denied previous comorbidities, smoking and alcoholism. He woke up with vertigo, associated with dysarthria and ataxia in the left side of the body. Two weeks after the onset of symptoms, he evolved with gait alteration and began to have episodes of painful, intermittent muscle spasms in the left upper and lower limbs. He presented negative serology for human immunodeficiency virus, syphilis and viral hepatitis, in addition to nonreagent rheumatological markers. Magnetic resonance imaging revealed a focus of signal alteration affecting the corticosubcortical surface of the cingulate gyrus on the right side, possibly corresponding to an inflammatory/demyelinating process. Cerebrospinal fluid analysis showed the presence of oligoclonal bands and anti-GAD reagent, with non-reactive anti-aquaporin 4. Discussion: The typical symptomatology of SPS involves the musculoskeletal component, representing up to close to 93% of the symptoms referred by the patients. Among other predominant symptoms, pain (82%) and bulbar dysfunction (47%) stand out. Some patients may have atypical symptoms, especially during the onset of symptoms. The case exposes the predominance of vertigo and ataxic symptoms, unusual for this stage of SPS, which may lead to difficulties in the investigation. Conclusion: Recognizing the atypical patterns of clinical presentation is an important responsibility of the neurologist, since early diagnostic elucidation is essential for defining the patient’s prognostic determination therapy.
Multiple cerebral ring enhancing lesions: an atypical finding of high-grade glioma
Authors: Maffei Rafael Tuzino Leite Neves , Yankelevich Daniel Natalio Gauss , Soares Maria Carolina , Bernardes Leonardo de Sousa , Gambirasio Bruna Gutierres , Santos Adrialdo José
Published: July 2023

Introduction: High-grade gliomas are primary neoplasms of the central nervous system and can have multiple clinical and neuroimaging presentations. An unusual radiologic image can lead to diagnostic difficulty, and cancer treatment delay. In rare cases, primary brain tumor can mimic multiple abscesses in magnetic resoanance imaging (MRI). The aim of this paper is to describe a diagnostic challenge in MRI imaging of brain tumors. Case Report based on a retrospective analysis of the medical records of the patient. Case report: This case report describes a previously healthy 48-year-old male evaluated for a first episode of tonic-clonic seizure. Brain MRI showed multiple focal cerebral ring enhancing lesions, with centrally restricted diffusion and susceptibility-weighted imaging (SWI) demonstrating incomplete hypointense rims in the lesion margin. Infectious and neoplastic diseases were suspected, including brain abscess, primary brain tumors or metastases. The initial systemic investigation for infection and primary tumor was negative and brain biopsy showed nonspecific inflammation. Empirical antibiotic therapy was started, with no clinical response. To better elucidate the diagnosis, surgical resection of the lesions was undertaken. Histopathologic exam showed a high-grade glial tumor, with 20% Ki-67, ATRX and IDH1 mutation, which was compatible with Grade IV astrocytoma. Conclusion: Multiple cerebral ring enhancing lesions can be an atypical presentation of high grade glioma and a diagnostic challenge. In this cases SWI can help differentiate from brain abscess, which presents complete and smooth hypointense rims.
Acute myeloradiculitis due to herpes simplex virus in an immunocompetent woman: early response to acyclovir and complete recovery after treatment
Authors: Veras Fabrício Martins , Holanda Arthur Cesário de , Arca Vitor Maia , Oliveira Daniel Alves de , Oliveira Igor de , Melo Eduardo Sousa de
Published: July 2023

Case presentation: A 42-year-old female presented a febrile syndrome associated with acute urinary retention and constipation one week after noticing perineal painful and hyperemic vesicular lesions. Outpatient work-up yielded positive herpes simplex virus serologies (immunoglobulin M and immunoglobulin G) and oral acyclovir was started. She arrived at our service with no spontaneous diuresis; in addition, there were perineal and lower gluteal hypoesthesia, lower limb hyperreflexia and Babinski sign in the right foot. Thoracic and lumbar magnetic resonance imaging (MRI) with contrast was normal, as well as brain and cervical images posteriorly performed. Cerebrospinal fluid analysis showed lymphomononuclear pleocytosis and hypoglycorrhachia. Intravenous acyclovir (10 mg/kg every eight hours) was started and continued for 14 days; she presented spontaneous diuresis 12 hours after the first dose and progressively decreased intermittent catheter output. Methylprednisolone pulse therapy for five days was associated at D4 of acyclovir. She was asymptomatic at discharge. Discussion: Herpes simplex virus type 2 (HSV-2) myeloradiculitis is rare and often underdiagnosed. An attentive neurological exam is essential for suspicion. Edema and T2 weighted imaging hyperintensity are possible findings at MRI; however, no changes are observed in many cases. Currently, there is no robust evidence for treatment, usually based on intravenous acyclovir and/or corticosteroids in high doses. Our case had an early and remarkable response to acyclovir. Prognosis varies in the literature; recovery has been reported after acyclovir was started three months from onset. Conclusion: It is important to be aware of HSV-2 myeloradiculitis as a cause of acute urinary retention, even in immunocompetent patients. This case adds to the discussion about the role of acyclovir, given the lack of evidence for best treatment and its relation to prognosis
Acute pregabalin cerebellar ataxia
Authors: Silvério Gabriel André , Alves Renata Cristine , Possan Pedro Arthur , Marchetti Mateus Pinto , Weber Isabela Louise , Terra Vera Cristina , Socher Karen Luiza Ramos , Watanabe Nancy , Caggiano Carlos Cesar Conrado
Published: July 2023

Female patient, 65-year-old, complaining of imbalance and difficulty walking for 15 days, associated with dizziness and diplopia, with worsening symptoms in the last four days. In recent use of pregabalin 75 mg daily to treat chronic pain, with dose increase in the last four days. On examination, he presented ataxic gait, drunken speech, pendular reflex, dysmetria and dysdiadochokinesia. We opted for the suspension of Pregabalin and complementary investigation for cerebellar ataxia with imaging examination, examination of the cerebrospinal fluid (CSF) and laboratory tests. Magnetic resonance imaging showed mild microangiopathy with, no other findings. Normal CSF examination, including search for oligoclonal bands. The search for rheumatological antibodies, tumor markers and serologies was negative. After the suspension of Pregabalin, the patient showed progressive improvement, with total reversal of symptoms. Acute cerebellar ataxia is defined as a syndrome that occurs in less than 72 hours in previously healthy individuals. It is clinically characterized by loss of balance and coordination. A heterogeneous group of conditions can cause the syndrome, including toxic causes. Several drugs cause ataxia, depending on the dose and duration of exposure. Although uncommon, anticonvulsants cause movement disorders, including pregabalin. Most adverse effects of this class of drugs occur within the first two weeks, ranging from mild to moderate. Movement disorders are rare, but when found they usually appear as ataxia or tremor. Acute cerebellar ataxia comprises a spectrum of neurological disorders in which ataxia is the main symptom. The heterogeneity of the etiologies of cerebellar ataxia is wide and requires hospitalization and extensive laboratory investigation. Among the causes, even if rare, is the use of pregabalin, widely used in clinical practice to treat neuropathic pain.
Genetic profiling of RYR1- related myopathy in a tertiary neuromuscular center
Authors: Fonseca Alulin Tácio Quadros Santos Monteiro
Published: July 2023

Introduction: The RYR1 gene encodes the skeletal muscle ryanodine channel, an ion channel responsible for regulating calcium release from the sarcoplasmic reticulum. Variants in RYR1 are cause of a wide phenotype of myopathies, with autosomal dominant and recessive inheritance. Objectives: In this work we present the clinical and genetic data of 43 patients with myopathies presumably related to the RYR1 gene, carrying 47 different variants Material and methods: Clinical and genetic data are presented. RYR1 gene were analyzed by next-generation sequencing. Results: Twenty patients have an autosomal dominant (AD) inheritance pattern, with 16 different variants observed. All AD variants were missense. The c.14582G>A, p.(Arg4861His) variant was the most recurrent in the AD group (three patients). Seventy-five percent of these variants were found in the channel and activation core region, especially in the transmembrane domain. In the presumed autosomal recessive inheritance (AR) pattern group, 23 patients were included, with 31 different variants described, the majority being missense variants (23). Eight were null variants (four splice site, two frameshift, one nonsense and one copy number variation). The c.7027G>A, p.(Gly2343Ser) variant was the most recurrent in the AR group (four patients). Conclusion: Autosomal dominant forms of RYR1-related myopathy are related to missense variants usually located in the channel and activation core region. Missense variants are also the main type observed in autosomal recessive forms, but in this AR group, null variants are also found, with no specific cluster along the gene.
Mathematical and artificial neural network modeling of hot air drying kinetics of instant “Cẩm” brown rice
Authors: LOAN Le Thi Kim , THUY Nguyen Minh , TAI Ngo Van
Published: July 2023

Modeling moisture content variation under variable hot air dryers is challenging. In this study, mathematical models and artificial neural network (ANN) were investigated for modeling of instant “Cẩm” brown rice drying process. The experiments were done in four levels of hot air temperature (55, 60, 65, and 70 °C). The results demonstrated that among eight mathematical models, the diffusion approach could give the best prediction of moisture ratio during the drying process with the highest R-square and lowest mean square error. Besides, the ANN model with 10 hidden layers also could provide the best-fit model with the same criteria as the mathematical model. Compared with the ANN model, both can give a highly accurate prediction. However, the ANN model could be more beneficial in the up-scale process.
Researching disinformation using artificial intelligence techniques: challenges
Authors: REPEDE Ștefan Emil
Published: July 2023

The present article aims to address a series of problems generated by the use of artificial intelligence models for the study of the creation and dissemination of false information beginning from the difficulties in defining and classifying established terms, continuing by exemplifying the way some of the established databases in the research field of fake news are built and ending by noting the differences in their labeling
Leadership, competitive intelligence and Robert Oppenheimer’s pivotal role in the dawn of the nuclear age
Authors: BĂLAN-LISEANU Rodica-Cristina
Published: July 2023

In an era of globalization, innovation, and competitive intelligence, the nuclear supply chain is continually evolving and increasing its capabilities. The top-secret operation ALSOS plays a key role in the (re)evolution of atomic energy as the energy of the future, with a constant focus on the responsible use of atomic energy. The US, a nuclear hegemon, has harnessed its leaders to their full potential, with J. Robert Oppenheimer being one of the leading names in charismatic, competitive, and transformational leadership. Through qualitative and content analysis, this article proposes a reflection on the origins and evolution of change in the nuclear field, in a continuous struggle for supremacy, connecting with current desiderata in the sphere of innovation, built on different leadership styles. The interest in leadership is recurrent, and the model of Operation ALSOS, in line with the iconic figure of J. Robert Oppenheimer, is representative of motivating the harnessing of new promises to inspire and revolutionize the world.
GRADO DE SATISFACCIÓN, FORTALEZAS Y DEBILIDADES DE LOS EGRESADOS DE LA FACULTAD DE ODONTOLOGÍA DE LA UNIVERSIDAD DE CUENCA ECUADOR, 2021-2022
Authors: Ortiz Banegas Samantha , Quizhpe Albarracín Katherine Cristina , Guapacasa Alexandra , Bravo Calderón Manuel Estuardo
Published: July 2023

La calidad de un servicio se mide por la satisfacción que proporciona al usuario, por lo tanto, para medir la calidad educativa de una institución de educación es necesario conocer la satisfacción de los receptores de los servicios, es decir, los estudiantes. Objetivo: identificar el nivel de satisfacción de los egresados de la Facultad de Odontología de la Universidad de Cuenca durante los años 2021 y 2022. Materiales y métodos: estudio de tipo observacional, descriptivo y transversal. Se evaluaron 30 egresados de la Facultad de Odontología a través de un cuestionario autoadministrado mediante una encuesta online haciendo uso del cuestionario SEUE. Resultados: el 63.3 % de  la población fueron egresados en el año 2022 y un 36.7% en el año 2021. Para determinar el nivel de satisfacción total se utilizó la fórmula (Grado de satisfacción = V / N), la sumatoria de la valoración en cada uno de los noventa y tres ítems del cuestionario fue 9478, dando como resultado 315.93, el cual representa un grado de satisfacción general bastante satisfecho. Conclusiones: Identificar las fortalezas y debilidades de una institución a través de la satisfacción de los estudiantes es un aspecto relevante para lograr el cumplimiento de los objetivos estratégicos y poder mejorar aspectos que ayuden a la institución y su formación.
ORGANIZATIONAL CULTURE OF THE INDONESIAN AIRPORT MANAGEMENT COMPANY : A CASE STUDY AT PT. ANGKASA PURA I
Authors: Edward Efendi Silalahi
Published: July 2023

The study aim at analyzing   the organizational culture structuring seen from the perspective of 7s Mc Kinsey and analyzing the organizational culture contributions against crucial success factors on the company's financial performance aspect. Qualitative research use with the case study approach at PT Angkasa Pura I as a commercial  transport management company, which is one of the Indonesian states - owned  enterprises.  Desain explorative and descriptive use complement this research. Data collection do through observation, interviews, literature study, and focus group discussion. Data analysis doing by a successive approximation technique. The results showed that seven components include structure, systems, style, staff, skill, strategy, and shared value/superordinate goals in the organization's effects and influenced by the culture of the organization, so the setup or repair of system components will affect the organizational culture. Similarly, the setup or improvement of the cultural organization will affect the organizational system components. Also, research results show that the development of organizational culture and on going socialization affects the growth of profitability (ROA, ROE).
Redução relativa da motilidade twitching de Pseudomonas aeruginosa TGC-04 exposta à cafeína
Authors: Gouveia Clóvis Queiroz , Oliveira Bianca Teixeira de Morais , Vasconcelos Ulrich
Published: July 2023

A motilidade twitching deixa Pseudomonas aeruginosa mover por sobre superfícies bióticas e abióticas, permitindo sua rápida colonização em novas superfícies. Perturbações na motilidade twitching influenciam a adesão. Este trabalho teve por objetivo verificar a ação da cafeína sobre a motilidade da linhagem P. aeruginosa TGC-04 e em seguida, avaliar a adesão da linhagem exposta à 2064 µg/mL de cafeína, previamente irradiada com luz de LED de alta potência a 700 nm por 10 minutos (1000 mW/cm2).  Foram realizados testes de motilidade swarming, swimming e twitching por 48h à 30ºC. O biofilme formado após incubação nas mesmas condições foi quantificado pelo método do cristal violeta. A taxa de adesão foi calculada pela diferença da absorbância do tratamento, em relação ao controle. Não houve perturbação nas motilidades swarming e swimming, contudo, a motilidade twitching foi reduzida ≈44%, refletindo na diminuição entre ≈60 e 80% da adesão das células, cujo grau de inibição foi considerado moderado, com as células moderadamente aderidas à superfície. Em complemento, foram identificadas células tipo swarm.
Seleção de linhagens de milho para produção de forragem, caracterização dos componentes da planta e fatores ambientais: uma revisão
Authors: Spada Cecilia Aparecida , Faria Marcos Ventura , Bonato Francieli Gesleine Capote , Oliveira Valdinei Caetano , Bordini Tomaz Carlos Eduardo , Martins de Mello Nicholas , Romero Gonçalves Gustavo , Otutumi Luciana , Bonato Denis Vinicius
Published: July 2023

Objetivou-se realizar uma breve revisão sobre as características desejáveis a serem buscadas em um programa de melhoramento de milho forrageiro, levando em consideração a qualidade da fibra, a textura do grão e a época de semeadura. A planta de milho para produção de silagem é a que apresenta elevada produção de grão com alta disponibilidade de amido e alta digestibilidade de fibra, produção de massa. No Brasil predominam genótipos de milho com grão tipo flint (duro), e isto é indesejável para produção de silagem devido à baixa digestibilidade do amido, a disposição físico-química dos grânulos de amido é a responsável por esta menor digestibilidade quando comparada aos grãos tipo dentados.  Outro ponto a ser considerado é a época de semeadura sendo que cada região bem como cada cultivar de milho tem suas características climáticas próprias as quais devem ser respeitadas para que o genótipo consiga expressar sua produção e qualidade. Desta forma, textura do grão bem como relação colmo e folha são os pontos chaves a serem selecionados com o objetivo de produzir híbridos com aptidão forrageira, lembrando que estas características só serão expressadas corretamente se respeitado a época de semeadura de cada material.
Vivências e trajetórias terapêuticas de usuários com câncer residentes em um município do Nordeste brasileiro
Authors: Monteiro Priscila Mikaelly Fernandes , Araújo Janieiry Lima de , Sena Rômulo Mágnus de Castro , Nascimento Ellany Gurgel Cosme do , Vasconcelos Renata Borges de , Ferreira Deyvson Alexandre , Cavalcanti Marília Abrantes Fernandes , Silva José Ednardo Soares Pereira da
Published: July 2023

Estudo qualitativo que objetivou analisar as vivências de usuários com câncer em suas trajetórias de busca por tratamento. Foram entrevistados 23 sujeitos, residentes no município de Pau dos Ferros/RN e cadastrados no Núcleo de Apoio aos Pacientes com Câncer. A interpretação das informações se deu por meio da Análise Temática e resultou em quatro categorias: 1) Eu sou ou eu estou doente? Entendimentos sobre o estado de boa saúde; 2) A luta diária contra o câncer: práticas terapêuticas e apoio social buscado pelo usuário oncológico; 3) Organização e deficiências dos serviços de saúde no acesso/assistência ao usuário oncológico; e 4) Trajetórias terapêuticas e impasses enfrentados no caminhar pela rede de atenção oncológica. Os resultados mostraram que as fragilidades com que opera a rede de atenção em oncologia no estado do Rio Grande do Norte (RN), repercutem em diversos modos de percepção sobre a doença, vinculação aos serviços e adesão ao tratamento, que por sua vez refletem as trajetórias terapêuticas empreendidas pelos usuários residentes no interior do estado.
Ocimum basilicum Linn. como estratégia natural ao uso de acaricidas sintéticos
Authors: Mello Peixoto Erika Cosendey Toledo , Breunig Ketlin Paôla , Gobatto Vitor Hugo do Nascimento , Kubo Fabiana Samara , Alves Isadora dos Santos , Silva Regildo Márcio Gonçalves
Published: July 2023

Rhipicephalus (Boophilus) microplus determina importantes prejuízos para bovinocultura. Porém, seu frequente controle pelo uso de acaricidas sintéticos, favorece além da resistência farmacológica, a presença de resíduos medicamentoso nos alimentos e meio ambiente. Assim, objetivou-se avaliar ação acaricida do óleo essencial de manjericão e seu hidrolato, sobre carrapatos bovinos. Utilizando o teste de imersão de adultos, foram avaliadas as taxas de mortalidade e oviposição do óleo essencial de manjericão (OEOb) 10, 20 e 30%, seu hidrolato 10, 20, 30 e 100%, além dos tratamentos controles negativo e testemunha. OEOb 10% determinou 53% de mortalidade não sendo possível observar melhores resultados quando aplicadas maiores concentrações, semelhantemente ao observado para seu hidrolato 100%. Com relação à taxa de oviposição, nenhum tratamento foi capaz de determinar inibição. Embora moderada, a mortalidade determinada pelo OEOb 10% pode contribuir para minimizar o uso de pesticidas sintéticos. Este fato é particularmente importante para sistemas orgânicos de produção animal, uma vez que acaricidas químicos sintéticos comprometem a certificação e seus produtos.
A Acurácia do fluxo de caixa descontado mediante os diferentes estágios do ciclo de vida empresarial
Authors: Brucoli Filho Nilton , Olivo Rodolfo Leandro de Faria , Davanso Rogerio Eufrosino , Perez Paloma Rubinato , Piva Graziele Maria
Published: July 2023

O atual cenário de negócios é marcado pela competição de organizações de diferentes modelos, perfis e estágios de desenvolvimento de organizações, dificultando o trabalho de quem se propõe a avaliar o valor de empresas. O objetivo do estudo foi verificar se a aplicação do método do Fluxo de Caixa de Descontado explica de forma mais satisfatória o valor de mercado de empresas brasileiras em algum dos estágios de desenvolvimento. O método investigou 117 empresas organizações listadas na Bolsa de Valores do Brasil (B3), comparando as médias da razão entre os valores obtidos pelos cálculos de perpetuidade de fluxos de caixa e os valores de mercado das empresas na data da pesquisa, considerando-se a classificação do estágio de desenvolvimento para agrupamento das observações. Os resultados indicam que o modelo de Fluxo de Caixa Descontado possui melhor aplicabilidade em empresas do estágio de maturidade.