bluuebunny/crossref_metadata_2025 huggingface dataset:
Hepatoprotective effect of Pinostrobin against Thioacetamide-induced liver cirrhosis in rats
Authors: Jabbar Ahmed Aj. , Abdulla Mahmood A.
Published: November 2022

Pinostrobin was used in traditional medication for management of numerous syndromes. In the current study, histology, immunohistochemistry, and hepatoprotection effects of Pinostrobin were assessed against thioacetamide (TAA) hepatotoxicity in rats. Thirty rats were arbitrarily separated into five groups. Group 1 was intraperitoneally (i.p) injected with distilled water 3 times/week and fed (po) daily with 10% Tween 20 for 2 months. Group 2–5 were i.p. injected with 200 mg/kg TAA thrice weekly for 8 weeks and fed with 10% Tween 20, 50 mg/kg silymarin, 30 and 60 mg/kg of Pinostrobin daily for 8 weeks, respectively. Experimental groups fed groups showed that Pinostrobin significant reduction in liver index and hepatocyte proliferation with much lesser cell injury. These groups were significantly down-regulated the PCNA and α-SMA. The liver homogenate exhibited increased antioxidant enzymes (SOD and CAT) activities accompanied with decline in malondialdehyde (MDA) level. The serum level of bilirubin, total protein, albumin and liver enzymes (ALP, ALT, and AST) were restored to normal and were comparable to that normal control and silymarin with TAA treated groups. The hepatotoxic group showed a significant rise in serum liver biochemical markers together with a considerable decrease in protein and albumin level compared to the normal group. The hepatotoxic group displayed decreased catalase and superoxide dismutase activities while increased lipid peroxidation. Pinostrobin decreased level of TNF-a, IL-6 and increased the level of IL-10. Acute toxicity with a higher dose of 500 mg/kg Pinostrobin did not manifest any toxicological signs in rats. Macroscopy of hepatotoxic liver exhibited irregular, rough surface with micro and macro nodule. Histopathology stained by Hematoxylin and Eosin, and Masson Trichrome showed there was inflammation and infiltration of lymphocytes, focal necrosis, fibrosis, and bile duct propagation. Pinostrobin fed group had expressively reduced TAA toxicity in gross and histology as designated by fewer disturbances of hepatic tissue, slight fibrosis, and low-grade cells infiltration. Immunohistochemical staining designated that pinostrobin significantly down-regulated the expression of proliferation cellular nucleus antigen (PCNA) and alpha-smooth muscle actin (α-SMA) in the liver. Thus, the findings of this study presented that the hepatoprotective effect of this plant may be due to a reduction in toxicity, inhibition of hepatocytes proliferation, down-regulation of PCNA and α-SMA, decreased enzyme markersand increased protein and albumin increased endogenous enzymes and reduced lipid peroxidation level.
Nickel Nanoparticles Anchored on Bentonite Clay for Methane Decomposition with Ordered Carbon as a Product
Authors: Motta Rayssa , Dornelas Camila , de Almeida Rusiene
Published: November 2022

Catalysts were synthesized with Ni and bentonite clay, without previous treatment, through wet impregnation with 5, 10 and 20% of Ni (m/m). They were characterized by energy dispersive X-ray fluorescence spectrometry (EDX), X-ray diffraction (XRD), temperature-programmed reduction (TPR), thermogravimetric analysis (TGA), adsorption and desorption of N2 at 77 K, and transmission electron microscopy (TEM). The catalytic activity in relation to the methane conversion reaction was evaluated at 500 °C for 0.5 h. The addition of 10 and 20% of nickel to the clay led to a disordered bentonite structure, characterized by the disappearance of the 001 reflection on the X-ray diffractograms, with a consequent increase in the interaction between nickel oxide and clay (TPR). All catalysts synthesized showed catalytic activity in relation to the conversion of methane to form ordered carbon. The catalyst with 20% of nickel had the highest activity, with 74% of methane conversion.
Corporate Social and Environmental Responsibility in SOE Mining Sector in Indonesia: Commitment of Social-legal Awareness
Authors: Disyon Huta , Widianingsih Widianingsih , Rio Fildzah
Published: November 2022

Through its Corporate Social and Environmental Responsibility (CSER), the company actively contributes to addressing social vulnerability issues in communities. However, given that businesses are also impacted financially, it is interesting to find out why companies, especially State-Owned Enterprises (SOE), continue to run their CSER programs, whether it is merely an obligation due to regulatory orders or whether there are other motives. This research was conducted from the perspective of the sociology of law. The result shows that the obligation of CSER in several regulations is not merely the lawgiver's own desires but comes from social awareness, given that kinship has existed for a long time. Even though there are no explicit restrictions addressing requirements or sanctions to implement CSER in the SOE Law, SOEs in the mining sector demonstrate their commitment to social awareness by continuing to carry out their CSER program in 2020 and 2021.
Modal analysis of a milling dynamometer considered as 1DOF system
Authors: Mupona Munyaradzi Innocent , Roșca Ioan Călin
Published: November 2022

A force transducer-based plate dynamometer for milling force measurements is presented in this paper. The main components of the designed dynamometer were described, and experimental modal analysis was carried out while considering the dynamometer as a 1DOF system. The values of the main components of the 1DOF systems such as mass, damping coefficient, and equivalent stiffness were identified, and the natural frequency for rings and dynamometer was calculated. The calculated natural frequencies of components were found in reacceptance FRF, obtained by modal analysis done with an impact hammer. A MATLAB simulation was done to validate the system using the transfer function based on the modal test.
Tracking the damages of the Shaheen cyclone in the Sultanate of Oman
Authors: Ibrahim Osama Ragab , Al-Amir Maryam , Al-Maghawry Salma
Published: November 2022

The Sultanate of Oman is in the south-eastern part of the Persian Gulf. Oman's coast causes Oman to be exposed to tropical cyclones occasionally. The damages occur when hurricanes reach the land, but some hurricanes dissipate in the sea without any noticeable harm. Generally, these strong storms hit Oman every 3 or 4 years between June and October, and it is mostly in the southern part of the Sultanate. One of these cyclones was Gonu on June 1, 2007, which caused 50 deaths in total and the damaged areas cost around $4.2 billion (2007 US dollars). This paper reviews and tracks the tropical cyclone Shaheen, which hit the Omani coast on October 2, 2021. We have used the hydrological data of previous cyclones to state the level of damage the cyclone caused. As expected, the cyclone caused a lot of human and material losses in a very short period due to the inadequate flood drain systems in Al-Khaboura city. Results showed the necessity of a proper stormwater drainage system to be installed in the northern cities of Oman. These effects were followed by a 2-day holiday for both government and private sectors for the sake of people's safety.
Gastrointestinal, Liver, Pancreas, Oral and Psychological Long-term
Symptoms of COVID-19 After Recovery: A Review
Authors: Afrisham Reza , Jadidi Yasaman , Davoudi Maryam , Moayedi Kiana , Soliemanifar Omid , Eleni Xirouchaki Chrysovalantou , Ashtary-Larky Damoon , Seyyedebrahimi Shadisadat , Alizadeh Shaban
Published: November 2022

Abstracts:

Due to the importance of control and prevention of COVID-19-correlated long-term symptoms,
the present review article has summarized what has been currently known regarding the molecular
and cellular mechanisms linking COVID-19 to important long-term complications including
psychological complications, liver and gastrointestinal manifestations, oral signs as well as even
diabetes. COVID-19 can directly affect the body cells through their Angiotensin-converting enzyme 2
(ACE-2) to induce inflammatory responses and cytokine storm. The cytokines cause the release of
reactive oxygen species (ROS) and subsequently initiate and promote cell injuries. Another way,
COVID-19-associated dysbiosis may be involved in GI pathogenesis. In addition, SARS-CoV-2
reduces butyrate-secreting bacteria and leads to the induction of hyperinflammation. Moreover,
SARS-CoV-2-mediated endoplasmic reticulum stress induces de novo lipogenesis in hepatocytes,
which leads to hepatic steatosis and inhibits autophagy via increasing mTOR. In pancreas tissue, the
virus damages beta-cells and impairs insulin secretion. SARS-COV-2 may change the ACE2 activity
by modifying ANGII levels in taste buds which leads to gustatory dysfunction. SARS-CoV-2
infection and its resulting stress can lead to severe inflammation that can subsequently alter
neurotransmitter signals. This, in turn, negatively affects the structure of neurons and leads to mood
and anxiety disorders. In conclusion, all the pathways mentioned earlier can play a crucial role in the
disease's pathogenesis and related comorbidities. However, more studies are needed to clarify the underlying
mechanism of the pathogenesis of the new coming virus.
Inflammation as Treatment Target for Status Epilepticus
Authors: Rejdak Konrad , Pikulicka Agata , Piekarska Małgorzata , Pacek Katarzyna , Płachta Kamila
Published: November 2022

Background:

Status epilepticus (SE) is a serious neurological disease that manifests as prolonged
seizures that last more than 5 minutes and between such episodes, patients do not regain consciousness.
It can result in cognitive defects, brain damage, or even death. It is commonly known that
one of the causes can be an inflammatory process, but here we will focus on inflammation as a result
of new onset refractory status epilepticus and, related to this, new promising forms of SE treatment.
Particular emphasis has been focused on new-onset refractory status epilepticus (NORSE).

Methods:

Based on public research databases, drugs with anti-inflammatory activity – commonly used
in different spheres of medicine – have been reviewed as potentially treating status epilepticus.

Results:

There is seizable clinical research suggesting that drugs that decrease inflammatory processes
might be effective in terminating status epilepticus.

Conclusion:

There is growing evidence showing that adding anti-inflammatory drugs to basic antiepileptic
treatment enhances the efficiency of the therapeutic process, with special potential in NORSE
cases.
The Regulated Cell Death and Potential Interventions in Preterm Infants
after Intracerebral Hemorrhage
Authors: Wu Yanan , Sun Yanyan , Wang Xiaoyang , Zhu Changlian
Published: November 2022

Intracerebral hemorrhage (ICH) in preterm infants is one of the major co-morbidities of preterm
birth and is associated with long-term neurodevelopmental deficits. There are currently no widely
accepted treatments to prevent ICH or therapies for the neurological sequelae. With studies broadening
the scope of cell death, the newly defined concept of regulated cell death has enriched our understanding
of the underlying mechanisms of secondary brain injury after ICH and has suggested potential interventions
in preterm infants. In this review, we will summarize the current evidence for regulated
cell death pathways in preterm infants after ICH, including apoptosis, necroptosis, pyroptosis, ferroptosis,
autophagy, and PANoptosis as well as several potential intervention strategies that may protect
the immature brain from secondary injury after ICH through regulating regulated cell death.
Acemannan from Aloe vera Extract: A Catalyst-Free, Approach for the
Access of Imidazole-Fused Nitrogen-Bridgehead Heterocycles
Authors: Baranwal Jyoti , Singh Swastika , Kushwaha Smriti , Jyoti Archana
Published: November 2022

A series of 2-phenyl substituted imidazo-pyridines, pyrazines and pyrimidines were synthesized
through an efficient one-pot, environmentally benign, and regioselective strategy which involves
the reaction between 2-bromocarbonyl compounds and 2-aminopyridines, 2-aminopyrazines, 2-
aminopyrimidines, respectively using aloe vera/water (3:2) as a green promoting media. To the best of
our knowledge, this is the first aloe vera promoted protocol for the synthesis of this important scaffold
having potential applications in medicinal and materials chemistry. The use of aloe vera as a biorenewable
and biodegradable reaction medium-cum-promoter, operational simplicity, use of readily
available substrates, mild reaction conditions, broad substrate scope, short reaction time, easy workup,
and high yields, makes the disclosed protocol a superior alternative to existing methods. Substituted
imidazo-pyridines, pyrazines and pyrimidines were obtained with 95%, 76% and 84% yields, respectively.
Thermodynamics, Kinetics and Isotherms Studies for Sorption of Direct
and Disperse Dyes onto Eco-friendly Pre-treated Cellulose Acetate Fabric
using Ultraviolet Irradiation
Authors: Zolriasatein Ali Akbar
Published: November 2022

Introduction:

Owing to the restoration of hydroxyl groups, cellulose acetate fibers can be dyed
with direct dyes. There are some drawbacks in the conventional deacetylation process of cellulose acetate
from environmental point of view.

Methods:

This process involves high temperature, alkalinity and large volume of effluent. The goal of
this work is to improve the dyeing properties of cellulose acetate fabric using an eco-friendly treatment
process. In this paper, cellulose acetate fabric was treated with ultraviolet light (UVB) at an air pressure
of 1 atm to improve dyeability. Then, the untreated and UV treated fabrics were dyed with direct and
disperse dyes. UV treated cellulose acetate fabric showed higher dye adsorption compare to that of untreated
cellulose acetate fabric. Five adsorption isotherm models including sold solution, Langmuir,
Freundlich, Temkin and BET were applied to determine the adsorption behavior. At all temperatures studied,
experimental data were better fitted with the Freundlich and Nernst models for direct and disperse
dyes respectively. Thermodynamic parameters such as change in free energy (ΔG0), the enthalpy (ΔH0),
and the entropy (ΔS0) were also evaluated.

Results:

The calculated thermodynamic values showed that the adsorption of these dyes onto the cellulose
acetate fabric was a physical adsorption process and endothermic in nature. These data also implied that
the adsorption of direct dye onto cellulose acetate fabric was spontaneous at the experimental temperature
range and adsorption of disperse dyes can be spontaneous at higher temperatures. Moreover, the ΔG0
values for the adsorption of disperse dyes onto the UV-treated fabrics were less than those for untreated
fabrics suggesting that UV treated fabrics require less external energy.

Conclusion:

Among the kinetic models studied, it was found that the pseudo second-order kinetic model
was the best model to describe the dye sorption process on the UV treated and untreated cellulose acetate
fabrics. The UV treatment led to an improvement in the boundary layer diffusion effect.
Introduction to Biomaterials and Scaffolds for Tissue Engineering
Authors: Hussain Khalil K. , Naeem Muhammad
Published: November 2022

Biomaterials are essential elements in various fields, especially medicine.
They can help restore biological functions and speed up the healing process after injury
or disease. Natural or synthetic biomaterials are used in clinical applications to provide
support, replace damaged tissue, or restore biological function. The study of such types
of biomaterials is an active area of research, particularly in the field of tissue
engineering (TE). In general, the term TE describes the regeneration, growth, and
repair of damaged tissue due to disease or injury. TE is a modern science that combines
biology, biochemistry, clinical medicine and biomaterials, which led to the research
and development of various applications. For example, in the field of regenerative
medicine, biomaterials can serve as a support (scaffold) to promote cell growth and
differentiation, which ultimately facilitates the healing process of tissues. This chapter
describes the various properties of biomaterials, a detailed discussion of scaffolds in
terms of design, properties and production techniques, and future directions for TE.
Electrospun Nanofibers Scaffolds: Fabrication, Characterization and Biomedical Applications
Authors: Oshi Murtada A. , Muhaymin Abdul , Safdar Ammara , Gul Meshal , Tufail Kainat , Khuda Fazli , Ullah Sultan , Fakhar-ud-Din  , Subhan Fazli , Naeem Muhammad
Published: November 2022

The electrospinning (ES) technique in the fabrication of biomaterials-based
electrospun nanofibers (ESNFs) has risen to prominence because of its accessibility,
cost-effectiveness, high production rate and diverse biomedical applications. The
ESNFs have unique characteristics, such as stability and mechanical performance, high
permeability, porosity, high surface area to volume ratio, and ease of functionalization.
The characteristics of ESNFs can be controlled by varying either process variables or
biomaterial solution properties. The active pharmaceutical agents can be introduced
into ESNFs by blending, surface modification, or emulsion formation. In this chapter,
in the first part, we briefly discuss the fundamental aspects of the fabrication,
commonly used materials, process parameters, and characterization of ESNFs. In the
second part, we discuss in detail the biomedical applications of ESNFs in drug
delivery, tissue engineering, and wound healings, cancer therapy, dentistry, medical
filtration, biosensing and imaging of disease.
Instagram Geotag
Authors: Dewi Ni Luh Desy Purnama , Sanica I Gede , Darma Gede Sri , Lestari Ni Putu Nina Eka
Published: November 2022

The purpose of the research conducted was to determine consumer satisfaction using the geotagging feature on Instagram social media. Provide information to readers who have an interest in using Instagram geotags to find out consumer behavior, especially consumer satisfaction. As reference material for future research on consumer satisfaction in influencing consumer behavior. This research is expected to play a role in the development of knowledge in the field of marketing management and can provide input and considerations to readers in analyzing changes in consumer behavior, especially in consumer satisfaction.
Influence of digital media on student practice of the faculty of philosophy, letters and educational sciences
Authors: Loor-Saltos Karla Nicole , Bravo-Barrezueta Silvia Lorena
Published: November 2022

The objective of this study is to determine the influence of digital media on student practice at the Faculty of Philosophy, Letters and Sciences of Education, given that it is of vital importance to guarantee that the infrastructure of digital media, keeping up with the current development of teaching and learning, in addition, educators and students should be encouraged to enjoy more in the use of these tools. The methodology applied in the research is descriptive, exploratory, field, and explanatory, with a mixed approach, that is, qualitative and quantitative, a structured survey was applied on a Likert scale, applied to 245 students. A high reliability of 0.842 was obtained through the SPSS statistic, which shows that digital media have an influence on student practice, generating benefits in the learning-teaching process.
Estimating the Economic Value of Automated Virtual Reality Cognitive Therapy for Treating Agoraphobic Avoidance in Patients With Psychosis: Findings From the gameChange Randomized Controlled Clinical Trial
Authors: Altunkaya James , Craven Michael , Lambe Sinéad , Beckley Ariane , Rosebrock Laina , Dudley Robert , Chapman Kate , Morrison Anthony , O'Regan Eileen , Grabey Jenna , Bergin Aislinn , Kabir Thomas , Waite Felicity , Freeman Daniel , Leal José
Published: November 2022

Background

An automated virtual reality cognitive therapy (gameChange) has demonstrated its effectiveness to treat agoraphobia in patients with psychosis, especially for high or severe anxious avoidance. Its economic value to the health care system is not yet established.

Objective

In this study, we aimed to estimate the potential economic value of gameChange for the UK National Health Service (NHS) and establish the maximum cost-effective price per patient.

Methods

Using data from a randomized controlled trial with 346 patients with psychosis (ISRCTN17308399), we estimated differences in health-related quality of life, health and social care costs, and wider societal costs for patients receiving virtual reality therapy in addition to treatment as usual compared with treatment as usual alone. The maximum cost-effective prices of gameChange were calculated based on UK cost-effectiveness thresholds. The sensitivity of the results to analytical assumptions was tested.

Results

Patients allocated to gameChange reported higher quality-adjusted life years (0.008 QALYs, 95% CI –0.010 to 0.026) and lower NHS and social care costs (–£105, 95% CI –£1135 to £924) compared with treatment as usual (£1=US $1.28); however, these differences were not statistically significant. gameChange was estimated to be worth up to £341 per patient from an NHS and social care (NHS and personal social services) perspective or £1967 per patient from a wider societal perspective. In patients with high or severe anxious avoidance, maximum cost-effective prices rose to £877 and £3073 per patient from an NHS and personal social services perspective and societal perspective, respectively.

Conclusions

gameChange is a promising, cost-effective intervention for the UK NHS and is particularly valuable for patients with high or severe anxious avoidance. This presents an opportunity to expand cost-effective psychological treatment coverage for a population with significant health needs.

Trial Registration

ISRCTN Registry ISRCTN17308399; https://www.isrctn.com/ISRCTN17308399

International Registered Report Identifier (IRRID)

RR2-10.1136/bmjopen-2019-031606
Leveraging mHealth and Patient Supporters for African Americans' and Latinxs' Engagement in HIV Care (LEAN): Protocol for a Randomized, Controlled, Effectiveness-Implementation Trial
Authors: Jones Joyce , McKenzie-White Jane , Saxton Ronald , Grieb Suzanne M , Nonyane Bareng , Graham Cadeesha , Cano Anthony , Johnson Sheridan , Childs Lanisha , Greenbaum Adena , Flynn Colin , Pearlowitz Marcia , Celano Shivaun , Chang Larry W , Page Kathleen R
Published: November 2022

Background

Despite substantial investments in ending the HIV epidemic, disparities in HIV care persist, and there is an urgent need to evaluate novel and scalable approaches to improving HIV care engagement and viral suppression in real-world settings.

Objective

This paper aims to describe a study protocol for a pragmatic type II hybrid effectiveness-implementation randomized controlled trial comparing existing standard of care clinic HIV linkage, adherence, and retention (LAR) protocols to a mobile health (mHealth)–enhanced linkage, adherence, and retention (mLAR) intervention.

Methods

The study will enroll 450 participants from clinics in Baltimore City. Eligibility criteria include being ≥18 years of age, having a new HIV diagnosis or being HIV-positive and out of care, or being HIV-positive and deemed by clinic staff as someone who could benefit from linkage and retention services. Participants randomized to the intervention receive mHealth-supported patient navigation for 12 months. Participants in the control group receive the referring clinic’s standard of care patient support. The primary outcome is HIV virologic suppression at 12 months. A subset of participants will be interviewed at 12 months to learn about their HIV care experiences and, for those in the intervention arm, their experiences with the mLAR intervention. This protocol was developed in collaboration with the Baltimore City Health Department (BCHD) and the Maryland Department of Health (MDH) and with input from a community advisory board.

Results

Enrollment began on February 25, 2020. As of August 11, 2022, 411 of the 450 target participants had been enrolled.

Conclusions

Pragmatic implementation science trials designed with input from key stakeholders, including health departments and community members, can help evaluate the evidence for mHealth interventions to reduce HIV health disparities.

Trial Registration

ClinicalTrials.gov NCT03934437; https://clinicaltrials.gov/ct2/show/NCT03934437

International Registered Report Identifier (IRRID)

DERR1-10.2196/42691
ENERGY MODELLING AND FORECASTING OF DAERAH ISTIMEWA YOGYAKARTA 2025
Authors: Haryono Eko , - Deendarlianto , Sopha Bertha Maya
Published: November 2022

Daerah Istimewa Yogyakarta (DIY) is one of the provinces in Indonesia which does not have a backup or potential sources of non-renewable primary energy. The non-renewable energy demand until this time, such as oil,coal and gas is supplied from the outside. DIY is in Java Madura Bali (JAMALI) interconnerction system and has not had a large-scale power systems. While DIY has renewable energy sources such as hydro, solar, wind, wave and biomass energy. These renewable energy sources are alternative energy that have not been optimally used. The lack of reserve energy resources that resulting dependence of energy supply from other areas should receive special attention from DIY government. To meet energy demand, the energy resources development is required. Due to the energy resources development requires a long time and high cost, it is necessary to be supported by good planning in energy policy.The purpose of this study is to determine the balance of energy demand and supply of  DIY until 2025. Furthermore, the purpose of this study is to find out a mix number of renewable energy. The Indonesian government has launched a vision of 25/25 which expection in 2025, the mix number of renewable energy will be 25%.The results of this study indicate that in 2025, the Transportion Sector is the largest energy user sector in DIY at 52.37%, followed by Household Sector (32.70%), Commercial Sector (8.26%), Other Sector (4.64%), and Industrial Sector (2.04%). The high level of energy consumption in the Transportation Sector is caused by the increasing number of vehicles especially motorcycles and passenger cars considering DIY is a student and tourism city. In term of the type of energy used, in 2025, the gasoline is the greatest type of energy demand (41.8%), followed by LPG (23.97%), electricity (18.14%) and diesel oil (11, 74%). This indicates that the fuel oil is still the main energy source for the DIY community activities. When viewed from supply side, most of the energy needs in DIY are supplied from outside. If the development of enewable energy targets DIY reached, the renewable energy mix is obtained by 0.53 %.
Lagu-Lagu Daerah Indonesia pada Panggung Musik Nasional 1950-1960an
Authors: Irawan Ricky
Published: November 2022

Lagu-lagu daerah telah memainkan peranan penting sebagai representasi keindonesiaan dalam ranah musik. Ia tidak hanya menjadi musik hiburan, namun juga diterima sebagai artikulasi kemajemukan dan kekayaan suku bangsa dan budaya Indonesia. Artikel ini bertujuan untuk menelusuri, kapan dan bagaimana lagu-lagu daerah muncul dan mendapatkan maknanya sebagai identitas keindonesiaan. Menggunakan pendekatan historis serta metode kajian literatur, lensa pengamatan diarahkan pada rentang 1950-1960an sebagai kurun di mana isu budaya daerah intensif memenuhi ruang-ruang diskurs nasional sebagai implikasi kebijakan budaya pemerintah Orde Lama pada masa Demokrasi Terpimpin. Hasil penelusuran mendapati bahwa kebijakan budaya pada kurun Demokrasi Terpimpin telah mendorong lembaga-lembaga kesenian, musisi dan industri rekaman memobilisasi lagu-lagu daerah Indonesia untuk tampil ke tengah panggung musik nasional sebagai identitas musik Indonesia sekaligus sebagai counter culture musik popular barat. Pada kurun itu untuk pertamakalinya, lagu-lagu yang hari ini dikenal sebagai lagu daerah direkam secara modern dalam bentuk piringan hitam oleh berbagai musisi dan perusahaan rekaman dalam negeri.
Tax burden and tax evasion in Brazil
Authors: Carvalho Hugo Leonardo Menezes de , Ávila Lucimar Antônio Cabral de
Published: November 2022

The study analyzed the relationship between the Brazilian tax burden and the country's level of evasion. The basis for the research stems from the fact that Brazil is considered a country whose tax burden is high and this would influence its level of evasion. However, there are international studies that have not identified significance in this relationship and, in the Brazilian case, despite being a widely discussed topic, the literature is incipient in testing this interaction. In view of this gap, the multiple linear regression method was used, based on data from the period from 2005 to 2015. The results showed that, in the Brazilian case, the tax burden presented statistical significance related to tax evasion, confirming the theoretical assumptions used. The present research also suggests that the Theory of Equity can be useful in improving the understanding of tax evasion behavior and the possibility of comparison with international studies.
Análisis de la enseñanza de la lectura crítica en la Educación Secundaria en Colombia y la necesidad de nuevas formas de intervenciones didácticas para su abordaje
Authors: Guerra Meza Pedro R.
Published: November 2022

Este artículo de reflexión es derivado de la investigación “Transformación de la Praxis Docente a través de un programa de formación en Pedagogía de Géneros Textuales para la enseñanza de la lectura crítica”, que se adelanta en la Universidad Metropolitana de Educación, Ciencia y Tecnología de Panamá. Este tiene como objetivo principal hacer un análisis de la enseñanza de la lectura crítica en la Educación Secundaria Colombiana, buscando, así, otras formas de mediación didáctica entre esta forma de hacer lectura y el estudiante. La metodología de este estudio fue de corte cualitativo y se optó por la revisión documental. Para ello fue necesario la lectura de fuentes bibliográficas que permitieran plantear discusiones, conjeturas y tensiones alrededor de la temática propuesta desde el objetivo. Los resultados principales indican que, por un lado, la lectura crítica no se está enseñando acorde con los cambios sociales, ni enfrentando los retos de la modernidad, y, por otra parte, se entiende que hay una ausencia del pensamiento crítico en la educación y este es reemplazado por el facilismo que brinda el internet. Se concluye, entonces, que existe la necesidad de buscar otras alternativas de enseñanza para la lectura crítica en la Educación Secundaria.
Domestic Waste Water Treatment by Combination of Root Zone Technology by Using Aquatic and Floating Macrophytes
Authors: Jirapure Tejswini , Nair Dr. Sindhu J.
Published: November 2022

Abstract: Every day, we face various environmental issues. The growing population and human activities deplete and degrade the quality and quantity of available water resources. Water is used for a variety of domestic and industrial purposes. Because of the rapid growth of industrialization and urbanization, water has become impure, containing so many insoluble materials and ingredients that it has become wastewater. Nowadays, the world is grappling with major water-related issues. Adopting welldefined methodologies at an affordable cost by utilizing natural resources is critical for effective water use. This project examines Root Zone Technology by using macrophytes, which is a low-cost and environmentally friendly method of wastewater treatment. To effectively treat domestic and industrial effluents, the root zone treatment and macrophytes treatment system uses a natural method.
Compulsory citizenship behavior and employees' contextual performance: Roles of perceived psychological safety and political skill
Authors: Hung Tsang-Kai , Lee Shu-Chuan , Wu Yung-Shun , Hsieh Hui-Min
Published: November 2022

We explored whether compulsory citizenship behavior (CCB) influenced employees' contextual performance via their perception of psychological safety, and examined whether political skill moderated this path. Participants were dyads formed by 139 supervisors and 534 subordinates from
businesses in Taiwan. The results reveal that CCB was negatively associated with contextual performance through the mediator of perceived psychological safety. However, there was no significant moderating effect of political skill. This study fills a gap in the literature on CCB. Our results
indicate that managers of organizations should pay attention to CCB and to their employees' mental health when trying to encourage enhanced work performance.
CONFESSIONAL AND CULTURAL INTERACTIONS IN THE POLITICAL SPACE OF RUSSIA: THEORETICAL ASPECT
Authors:   Russian Presidential Academy of National Economy and Public Administration, Daudov N.M.
Published: November 2022

Topical aspects of confessional and cultural interaction in the political space of Russia are considered. Special attention is paid to the characteristics of the main confessions in the political and legal space of Russia, the forms of their interaction with the state and among themselves are indicated. As a result of the analysis the conclusion about the need of further development and strengthening of cooperation between religious organizations in terms of counteracting the negative phenomena in society is made.
VIOLATION OF HISTORICAL JUSTICE AS A THREAT TO THE NATIONAL MENTALITY
Authors:   Russian Presidential Academy of National Economy and Public Administration, Kovalev A.A.
Published: November 2022

The negative influence on the perception of world and Russian history is seen as a threat to the national mentality, which is part of the national security of modern Russia. The interdependent relationship between the history of the people/state and its national mentality is shown. The author concludes that the situation of escalation in 2022 on the territory of Ukraine between Russia and the collective West demonstrates the clash of national mentalities on the basis of the historical injustice that has been forming for a long time.
DEVELOPING JOINT PROJECTS OF THE RUSSIAN FEDERATION AND AFRICAN COUNTRIES IN THE CONTEXT OF REGIONAL INTEGRATION ON THE CONTINENT
Authors:   Peoples’ Friendship University of Russia, Ahmat Idriss , Kanoute Soumaila ,   Peoples’ Friendship University of Russia
Published: November 2022

Various aspects of cooperation between Russia and the countries of the African continent, following the path of political, socio-economic, scientific and technological development are considered. The progressive development of trade and economic relations between Russia and the countries of the African continent, as well as ensuring growth in the field of energy, agriculture, use of mineral resources, development of infrastructure and high technology are analyzed. The necessity of development of joint projects between Russia and African countries in the context of regional integration on the continent is assessed.
Adıyaman Bayram Taplamasının Somut Olmayan Kültürel Miras Kapsamında Değerlendirilmesi
Authors: TÜRKOĞLU Turgut , SANDIKCI Mustafa , SARAÇ Ömer
Published: November 2022

Bu çalışmada Adıyaman’ın yöresel bir ürünü olan bayram taplamasının Adıyaman mutfağındaki yerinin, kültürel değerinin, üretim sürecinin ve bu süreçteki sosyo-kültürel işleyişinin belirlenmesi amaçlanmıştır. Araştırmada nitel veri toplama yöntemine başvurulmuş ve veriler yarı yapılandırılmış görüşme tekniği ile elde edilmiştir. Görüşme formu, bayram taplaması yapan yerel halk ve taplama üretiminde bulunan işletme yetkilileri olmak üzere 10 kişiye uygulanmıştır. Araştırmada bayram taplamasının Adıyaman’da yöresel bir lezzet olduğu, sevilerek tüketildiği, üretimi esnasındaki sosyo-kültürel işleyişin insanları olumlu etkilediği ancak üretiminde birtakım farklılıklar olduğu sonuçlarına ulaşılmıştır.
Design and Screening of Zwitterionic Polymer Scaffold for Rapid Underwater Adhesion and Long-term Antifouling Stability
Authors: Zhang Zekai , Han Xia , Gong Wei , Huang Kai , Li Jiahui , Chen Xueqian , Lian Cheng , Liu HongLai
Published: November 2022

As key components of antifouling material surfaces, the design and
screening of polymer molecules grafted on the substrate are critical.
However, current experimental and computational models still retain an
empirical flavor due to the complex structure of polymers. Here, we
report a simple and general strategy that enables multi-scale design and
screening of easily synthesized functional polymer molecules to address
this challenge. Specifically, the required functions of the antifouling
material are decomposed and assigned to different modules of the polymer
molecules. By designing different modules, a novel bio-inspired polymer
with three zwitterionic poly (sulfobetaine methacrylate) (PSBMA) chains,
three catechol (DOPA) anchors (tri-DOPA-PSBMA), and a tris(2-aminoethyl)
amine (TREN) scaffold were screened out. Moreover, it was successfully
synthesized via an atom transfer radical polymerization (ATRP). The
excellent performance of tri-DOPA-PSBMA with a versatile and convenient
grafting strategy makes it a promising material for marine devices,
biomedical devices, and industrial applications.
Rapidly progressive synovial sarcoma with multiple metastases leading to intestinal obstruction
Authors: Geng Ze , Yuan Xinwei , Xi Hongzhong , Liu Xin
Published: November 2022

A 34-year-old man complained of radiating pain in the left lower
extremity for 1 week,and diagnosed as soft tissue sarcoma of the left
hip with pulmonary metastasis.The postoperative pathology report was
poorly differentiated synovial sarcoma.Intussusception and liver
metastases were found 1 week after surgery,and then rapidly deteriorated
and died.
Loss of Anti-Spike Antibodies Following mRNA Vaccination for COVID-19 Among Patients with Multiple Myeloma
Authors: Stampfer Samuel D. , Bujarski Sean , Goldwater Merissa-Skye , Jew Scott , Regidor Bernard Sean , Chen Haiming , Xu Ning , Li Mingjie , Fung Eddie , Swift Regina A. , Beatty Bethany , Eshaghian Shahrooz , Inc. James Berenson, MD,
Published: November 2022

Background Multiple myeloma (MM) patients have variable
responses to mRNA vaccination to COVID-19. Little is known regarding
their vaccine-induced antibody levels over time. Methods We
monitored spike IgG antibody levels over 24 weeks among a subset of 18
MM patients who showed a full response after two mRNA vaccinations. MM
patients had a more rapid decline in antibody levels as compared to 8
healthy controls, with power law half-lives of 72 days (versus 107 days)
and exponential half-lives of 37 days (versus 51 days). Results
The patients with longer SARS-CoV-2 antibody half-lives were more likely
to have undetectable monoclonal protein than those with shorter
half-lives, suggesting better disease control may correlate with longer
duration of vaccine-induced antibodies. Regardless, by 16 weeks
post-second dose of mRNA vaccination, the majority of patients had
antibody levels below 250 binding arbitrary units per milliliter, which
would be unlikely to contribute significantly to preventing COVID-19.
Conclusions Thus, even MM patients who respond adequately to
vaccination are likely to require more frequent booster doses than the
general population.
Endocrinology: The utmost importance of ALPRAZOLAM in the treatment of NTBI-induced hyperadrenalism with epinephrine peaks and chronically elevated blood levels of adrenaline in rare degenerative diseases such as H63D syndrome
Authors: Diamandis Dr. Carolina , Makri Sofia , Smith Lucas , Steinberg Benjamin , Kipper Nicolas , Buchanan Robert , Pickar David
Published: November 2022

In 1992, our esteemed colleagues Alan Breier, Orlando Davis, Robert
Buchanan, Samuel J. Listwak, Courtney Holmes, David Pickar, and David S.
Goldstein published a seminal scientific paper titled “Effects of
Alprazolam on Pituitary-Adrenal and Catecholaminergic Responses to
Metabolic Stress in Humans.” In it, they described with high accuracy
the effects of benzodiazepines on stress-induced activation of the three
classic “stress” systems: Pituitary-adrenal, adrenal medullary, and
sympathoneural systems. The results provided an answer to a question
that is still being asked today: Why is alprazolam so much more
effective than all other benzodiazepines for certain anxiety-related
conditions, especially panic attacks? The colleagues found the answer to
that question, but although the work was impeccable, their findings
never made it into medical textbooks. What Breier et al. found was this:
Alprazolam is able to attenuate 2DG-induced activation of the HPA axis
and adrenomedullary activity, as evidenced by attenuated responses of
plasma levels of ACTH and epinephrine, respectively, without clinically
affecting other important responses of two indices of sympathoneural
activity. For the treatment of patients whose adrenal glands are working
in a highly dysfunctional or centrally dysregulated manner due to rare
diseases such as NTBI induced H63D syndrome, alprazolam is still the
first drug of choice - despite its dependence potential - to protect the
organism of the affected person from dangerous adrenaline excesses that
are way more dangerous than any well-monitored use of alprazolam.
Modelling of pedestrian-induced load in serviceability limit state analysis of footbridges
Authors: Spasojevic-Surdilovic Marija , Zivkovic Srdjan , Turnic Dragana , Milosevic Marko
Published: November 2022

The last few decades new trends in the design of pedestrian bridges have
resulted in lighter and more slender structures. This leads to a reduction
in natural frequencies and increased flexibility, and thus a greater
possibility for structures to become more exposed to excessive vibrations
caused by pedestrians. The lager amplitudes of vibrations occur if the pace
frequency of excitation load approaches one of natural frequency of
footbridge. The vibration of high proportions may cause pedestrians to feel
uncomfortable, sick or unsafe while crossing the bridge. In modern
pedestrian bridge design, human-induced vibrations have become an important
issue. Footbridge vibrations occur in vertical, lateral and longitudinal
direction, and torsion of the bridge deck is also possible. The main types
of pedestrian action on the bridge are walking and running, while jumping,
bouncing, swaying are considered to be intentional, or sometimes even vandal
excitation. Pedestrian-induced loads are difficult to model since
pedestrians may have different weight, various number in the groups randomly
distributed over the bridge deck. Also, the walking velocity may vary from a
pedestrian to a pedestrian. The load models appropriately set up are of
great importance for understanding the response of the bridge. Principles of
modeling of the human-induced load and some characteristic models of
pedestrian loads, described in proposals and codes, are presented in this
paper. Some results of Serviceability Limit State analysis, in terms of
human-induced vibration, of the pedestrian bridge over the Nisava River in
Nis, are also presented.
Tensile membrane structures at world fairs
Authors: Randjelovic Nemanja
Published: November 2022

World Fairs provide the opportunity for all nations to show their
achievements to the rest of the world. In addition to state of the art
developments in science, technology and culture, Expos also became the
showcase for architecture. The history of application of tensile membrane
structures at Expos started in 1958 in Brussels and continues until today.
This paper researches the progress of tensile membranes through the
structures built for World Fairs.
Remodeling Type 2 Diabetes Diagnosis: What Individuals Need for Success
Authors: Boakye Michelle D.S. , Miyamoto Sheridan , Greenwood Deborah , Van Haitsma Kimberly , Boltz Marie , Kraschnewski Jennifer
Published: November 2022

The diagnosis of type 2 diabetes initiates a new health-illness transition. However, little is known about the immediate support that people need to successfully cope with this diagnosis. This qualitative study explored the experiences and immediate support needed at the point of diagnosis among individuals with type 2 diabetes. The findings suggest the need for health care professionals to render immediate emotional support in the form of reassurance and partnership to manage the condition together. Pre- and post-counseling sessions can minimize the emotional and psychological strain associated with the new diagnosis. Individuals should be given information on available resources, as well as an immediate connection with a health care partner who can provide guidance and help with the transition.
The Impact of Carbamylation and Anemia on HbA1c’s Association With Renal Outcomes in Patients With Diabetes and Chronic Kidney Disease
Authors: Tang Mengyao , Berg Anders , Rhee Eugene P. , Allegretti Andrew S. , Nigwekar Sagar , Karumanchi S. Ananth , Lash James P. , Kalim Sahir
Published: November 2022

OBJECTIVE

Glycated hemoglobin (HbA1c) can predict risk for microvascular complications in patients with diabetes. However, HbA1c’s reliability in chronic kidney disease (CKD) has been questioned, with concerns including competition from another posttranslational protein modification, carbamylation, acting on the same amino groups as glycation, and anemia with reduced erythrocyte lifespans leading to altered glycation accumulation. We investigated whether carbamylation and anemia modify the impact of HbA1c on renal outcomes in patients with diabetes and CKD.

RESEARCH DESIGN AND METHODS

In 1,516 participants from the Chronic Renal Insufficiency Cohort study with diabetes and CKD, Cox regression models were applied to evaluate the association between HbA1c and CKD progression (composite of end-stage kidney disease or 50% decline in estimated glomerular filtration rate [eGFR]), stratified by carbamylated albumin (C-Alb) quartiles and anemia.

RESULTS

The mean eGFR was 38.1 mL/min/1.73 m2, mean HbA1c was 7.5% (58 mmol/mol), and median C-Alb was 8.4 mmol/mol. HbA1c was lower in the higher C-Alb quartiles. During a median follow-up of 6.9 years, 763 participants experienced CKD progression. Overall, higher HbA1c was associated with an increased risk of CKD progression (adjusted hazard ratio 1.07 [95% CI 1.02–1.13]). However, using stratified analyses, HbA1c was no longer associated with CKD progression in the highest C-Alb quartile, but did show a monotonic increase in CKD progression risk across each lower C-Alb quartile (P-interaction = 0.022). Anemia also modified the association between HbA1c and CKD progression (P-interaction = 0.025).

CONCLUSIONS

In patients with coexisting diabetes and CKD, the association between HbA1c and CKD progression is modified by carbamylation and anemia.
Leder: Tilhørighet: Å skape fellesskap i barnehagen
Authors: Johansson Eva M.
Published: November 2022

Att barn har rätt att uppleva tillhörighet till kamrater och vuxna i förskolan oavsett deras bakgrund, erfarenheter och kompetenser kan tyckas vara en självklarhet, men hur ser det ut i dagens förskola? Hur går det till när tillhörighet skapas i förskolan?
I det här temanumret utforskas tillhörighet i förskola– i vardagens olika samspel och i politiska dokument, och med hjälp av olika frågeställningar. Frågor som de olika studierna vill belysa är: Hur skapas tillhörighet? Hur inramas tillhörighet i policydokument? Hur ser tillhörighet ut i förskolans olika gemenskaper, för personal, barn och deras föräldrar?