bluuebunny/crossref_metadata_2025 huggingface dataset:
Digital health use and the likelihood of Neonatal Intensive Care Unit admissions: Opportunities and potential mechanisms for impact (Preprint)
Authors: Brinson Alison K , Jahnke Hannah R , Henrich Natalie , Moss Christa , Shah Neel
Published: January 2024

BACKGROUND

Background: Admission to the Neonatal Intensive Care Unit (NICU), is costly and has been associated with financial and emotional stress amongst families. Digital health may be well-equipped to impact modifiable health behaviors that contribute to NICU admission rates.

OBJECTIVE

Objective: To investigate how utilization of a comprehensive prenatal digital health platform is associated with gestational age at birth and mechanisms to reduce risk of admission to the NICU.

METHODS

Methods: Data were extracted from 3326 users who enrolled in a comprehensive digital health platform between January 2020 and May 2022. Multivariable linear and logistic regression models were used to estimate the association between duration of digital health utilization and gestational age at birth and mechanisms to reduce risk of a NICU admission. Multivariable logistic regression models estimated the associations between gestational age at birth and mechanisms to reduce risk of a NICU admission, and the likelihood of a NICU admission. All analyses were stratified by presence of any gestational conditions during pregnancy.

RESULTS

Results: For users both with and without gestational conditions, the duration of digital health utilization was positively associated with gestational age at birth and several mechanisms that have the potential to reduce risk of a NICU admission, including, learning medically accurate information, managing mental health, and identifying warning signs during pregnancy. For users with and without gestational conditions, an increase in gestational age at birth was associated with a decreased likelihood of NICU admission. Among users who developed gestational conditions, those who reported that the platform helped them understand warning signs during pregnancy had lower odds of a NICU admission [OR(95% CI)]= 0.63 (0.45, 0.89), p=0.009].

CONCLUSIONS

Conclusion: Digital health utilization may aid in increasing gestational age at birth and reduce risk of NICU admission.
Quality of Chronic Obstructive Pulmonary Disease Information on the Chinese Internet: Website Evaluation Study (Preprint)
Authors: Wang Qinqin , Liu Lingjun , Li Hong , Zhang Qiao , Ma Qianli
Published: January 2024

BACKGROUND

The development of internet technology has greatly increased the ability of patients with chronic obstructive pulmonary disease (COPD) to obtain health information, giving patients more initiative in the patient-physician decision-making process. However, concerns about the quality of website health information will affect the enthusiasm of patients’ website search behavior. Therefore, it is necessary to evaluate the current situation of Chinese internet information on COPD.

OBJECTIVE

This study aims to evaluate the quality of COPD treatment information on the Chinese internet.

METHODS

Using the standard disease name “慢性阻塞性肺疾病” (“chronic obstructive pulmonary disease” in Chinese) and the commonly used public search terms “慢阻肺” (“COPD”) and “肺气肿” (“emphysema”) combined with the keyword “治疗” (“treatment”), we searched the PC client web page of Baidu, Sogou, and 360 search engines and screened the first 50 links of the website from July to August 2021. The language was restricted to Chinese for all the websites. The DISCERN tool was used to evaluate the websites.

RESULTS

A total of 96 websites were included and analyzed. The mean overall DISCERN score for all websites was 30.4 (SD 10.3; range 17.3-58.7; low quality), no website reached the maximum DISCERN score of 75, and the mean score for each item was 2.0 (SD 0.7; range 1.2-3.9). There were significant differences in mean DISCERN scores between terms, with “chronic obstructive pulmonary disease” having the highest mean score.

CONCLUSIONS

The quality of COPD information on the Chinese internet is poor, which is mainly reflected in the low reliability and relevance of COPD treatment information, which can easily lead consumers to make inappropriate treatment choices. The term “chronic obstructive pulmonary disease” has the highest DISCERN score among commonly used disease search terms. It is recommended that consumers use standard disease names when searching for website information, as the information obtained is relatively reliable.
Sleep Quality in Pediatrics and Parental Stress in Neuromuscular Disorder: A Descriptive Study (Preprint)
Authors: Khaksar Sajjad , Jafari oori Mehdi , Sarhangi Forogh , Moayed Malihe Sadat
Published: January 2024

BACKGROUND

Neuromuscular diseases (NMDs) constitute a heterogeneous group of disorders that affect motor neurons, neuromuscular junctions, and muscle fibers, resulting in symptoms such as muscle weakness, fatigue, and reduced mobility. These conditions significantly affect patients' quality of life and impose a substantial burden on caregivers. Spinal muscular atrophy (SMA) is a relatively common NMDs in children that presents in various types with varying degrees of severity.

OBJECTIVE

This study aimed to evaluate the sleep quality of children with NMDs, particularly SMA types 1, 2, and 3, and assess the stress levels experienced by their parents.

METHODS

A descriptive analytical study was conducted from February to October 2023 in selected hospitals and dystrophy associations in Tehran and Isfahan, Iran. A total of 207 children aged 1–14 years with various NMDs were included in the study. Data were collected using a three-part online questionnaire: demographic information, Children's Sleep Habits Questionnaire (CSHQ) to assess children's sleep, and Stress Response Inventory (SRI) to measure parental stress. Statistical analyses were performed using SPSS version 22, with the significance set at P < .05.

RESULTS

Significant differences in sleep quality were found among SMA types, with mean scores of 74.76± 7.48 for SMA1, 76.4±07.29 for SMA2, 72.88±6.73 for SMA3, and 75.87±5.74for other NMDs (P = .025). A correlation was found between sleep and length of hospital stay (r = .234, P < .000), as well as sex (r = -.140, P = .043). Parental stress scores averaged 95.73±32.12. There was no statistically significant difference in parental stress scores among the four groups (P =.783). This suggests that parental stress levels were similar across different NMD groups.

CONCLUSIONS

Sleep disorders are prevalent among children with NMDs, especially SMA. Parents experience high levels of stress that can affect the care they provide. Therefore, interventions to improve children's sleep and address parental stress are crucial. Regular screening, counseling, and tailored support are recommended to enhance the well-being of children with NMDs and their families.

CLINICALTRIAL
ChatGPT Use Among Pediatric Health Care Providers: Cross-Sectional Survey Study (Preprint)
Authors: Kisvarday Susannah , Yan Adam , Yarahuan Julia , Kats Daniel J , Ray Mondira , Kim Eugene , Hong Peter , Spector Jacob , Bickel Jonathan , Parsons Chase , Rabbani Naveed , Hron Jonathan D
Published: January 2024

BACKGROUND

The public launch of OpenAI’s ChatGPT platform generated immediate interest in the use of large language models (LLMs). Health care institutions are now grappling with establishing policies and guidelines for the use of these technologies, yet little is known about how health care providers view LLMs in medical settings. Moreover, there are no studies assessing how pediatric providers are adopting these readily accessible tools.

OBJECTIVE

The aim of this study was to determine how pediatric providers are currently using LLMs in their work as well as their interest in using a Health Insurance Portability and Accountability Act (HIPAA)–compliant version of ChatGPT in the future.

METHODS

A survey instrument consisting of structured and unstructured questions was iteratively developed by a team of informaticians from various pediatric specialties. The survey was sent via Research Electronic Data Capture (REDCap) to all Boston Children’s Hospital pediatric providers. Participation was voluntary and uncompensated, and all survey responses were anonymous. 

RESULTS

Surveys were completed by 390 pediatric providers. Approximately 50% (197/390) of respondents had used an LLM; of these, almost 75% (142/197) were already using an LLM for nonclinical work and 27% (52/195) for clinical work. Providers detailed the various ways they are currently using an LLM in their clinical and nonclinical work. Only 29% (n=105) of 362 respondents indicated that ChatGPT should be used for patient care in its present state; however, 73.8% (273/368) reported they would use a HIPAA-compliant version of ChatGPT if one were available. Providers’ proposed future uses of LLMs in health care are described.

CONCLUSIONS

Despite significant concerns and barriers to LLM use in health care, pediatric providers are already using LLMs at work. This study will give policy makers needed information about how providers are using LLMs clinically.
Impact of Endometrioma Surgery on Fertility: A Prospective Cohort Study (Preprint)
Authors: mouzali Amal , Makhlouf Fayçal , Ziad Cheikh El Ghanama Mohamed
Published: January 2024

BACKGROUND

Endometrioma is often associated with infertility. While cystectomy can improve the pregnancy rate, it may also affect the ovarian reserve.

OBJECTIVE

This study aimed to investigate the impact of endometrioma cystectomy on ovarian reserve markers at 3 and 12 months after surgery in infertile women and to determine the postoperative pregnancy rate.

METHODS

This prospective, longitudinal, monocentric cohort study included 40 infertile patients aged 21–40 years with ovarian endometriomas measuring ≥4 cm in diameter and with good tubal patency and normal spermogram test results of the husband at the Gharafa Clinic, a gynecological and obstetric clinic annexed to the Bab El Oued University Hospital in Algiers. The main outcome measures were ovarian reserve (Antral Follicle Counts [AFC] follicle-stimulating hormone [FSH], and anti-Müllerian hormone [AMH] levels). We also calculate the number of follicles retrieved from cysts to evaluate their impact on the ovarian reserve and the spontaneous pregnancy rate.

RESULTS

After endometrioma cystectomy, the antral follicle count significantly increased at 12 months postoperatively (7.7±0.6 follicles before surgery vs. 8.5±0.5 follicles after surgery, p<0.001). The mean FSH levels did not increase; however, the AMH levels significantly decreased at 3 and 12 months postoperatively (2.29±0.26 ng/mL before surgery vs. 1.47±0.23 ng/mL at 3 months, p<0.001 and 1.46±0.20 ng/mL at 12 months, p<0.001). After stratification into three groups, decreased AMH levels after surgery showed a significant association with cystectomy associated with other surgical procedures, particularly in the presence of deep endometriosis. The number of follicles retrieved from cysts correlated with AMH levels preoperatively, but not postoperatively. Overall, 47.5% of patients had spontaneous pregnancies despite having low AMH levels; hence, surgery was considered to be effective.

CONCLUSIONS

Cystectomy can reduce the AMH level in cases of associated endometrioma but not in isolated endometrioma, the CFA increase and FSH doesn’t change. In fact this cystectomy can improve spontaneous pregnancy in half of cases.
High Potassium Diet Rich in Spices and Herbs-Salt Substitution (HPSH-SS) for Blood Pressure Reduction in Older Adults: Protocol for Diet Concept and Randomized Controlled Trial (Preprint)
Authors: Farapti Farapti , Putri Sheila Amara , Furqonia Annisaa Wulida , Rejeki Purwo Sri , Miftahussurur Muhammad
Published: January 2024

BACKGROUND

Hypertension increases with age, often due to high sodium (Na) and low potassium (K) intake. Reducing salt and increasing K intake is challenging, especially for older adults due to taste preferences. Culinary herbs and spices, rich in K, offer a potential solution. The High Potassium Diet Rich in Spices and Herbs-Salt Substitution (HPSH-SS) diet has not yet been studied for its effectiveness in lowering blood pressure.

OBJECTIVE

This study aims to create an HPSH-SS diet, analyze its effects on blood pressure in older adults, and study the molecular mechanism occurring in the kidneys and blood vessels influenced by this diet.

METHODS

This study consists of 2 phases. The first phase involved formulating and assessing the HPSH-SS diet tailored for older adults. The intervention group (IG) received a diet of 1800 kcal/day, with 3500 mg K and 1500 mg Na, while the control group (CG) received 1500 mg K and 2000 mg Na. The diet was administered for 14 days and standardized using the NutriSurvey program and biochemistry analysis by atomic absorbance spectrophotometry (AAS). The second phase was a 14-day parallel randomized controlled trial (RCT) with the older adult participants divided into IG and CG. Primary outcomes included blood pressure; serum potassium; aldosterone; F2 isoprostane; nitric oxide plasma levels; and urine analysis of Na, K, and the Na/K ratio. Confounding variables were controlled through randomization and stratified analysis.

RESULTS

The menu formulation and organoleptic assessment of the HPSH-SS diet began in mid-2022 and was approved by the Ethics Committee of the Faculty of Public Health at Universitas Airlangga (78/EA/KEPK/2022) on May 11, 2022. The diet was standardized to achieve daily nutritional values of 1800 kcal energy, 3500 mg K, and 1500 mg Na. K and Na contents were analyzed using AAS from several participants’ spice diet menus. Recruitment for the RCT started in March 2023, with approval from the Health Research Ethics Committee Universitas Airlangga School of Medicine, Surabaya (35/EC/KEPK/FKUA/2023). The study was registered from February 9, 2023, to February 9, 2024. Between March and June 2023, 64 participants were recruited, with 32 participants in the IG and CG. The intervention and data collection will take place over 1 year. Data management is in progress, and data analysis is yet to be performed.

CONCLUSIONS

This RCT protocol hypothesizes that the diet will increase serum K, plasma aldosterone, and nitric oxide levels; decrease plasma F2 isoprostane; increase urinary Na and K levels; lower the urinary Na/K ratio; and reduce systolic and diastolic blood pressure. If effective, it will offer valuable insights into dietary strategies for blood pressure regulation in older adults.

INTERNATIONAL REGISTERED REPORT

DERR1-10.2196/56869
Piloting an Educational Approach to Assess eHealth Literacy and Evidence-Based Medicine in Integrative Health: A Feasibility and Validation Study (Preprint)
Authors: Nault Daryl , Abatemarco Atiera , Missenda Marybeth , Cherpak-Castagna Christine , Moonaz Steffany
Published: January 2024

BACKGROUND

A core competency of integrative health (IH) education is applying evidence to clinical practice. Low rates of online health literacy put consumers at higher risk of misinformation. Practitioners may serve to reduce this risk. Integrative Health (IH) crosses multiple healthcare disciplines and is therefore well-suited to improve the health information ecosystem. IH practitioners must demonstrate evidence-based medicine (EBM) skills and electronic health information literacy (eHL) to make a positive impact. The Fresno Test of Evidence-Based Medicine (FEBM) is a validated, performance-based assessment used in medical education. However, the scenarios included in this assessment do not reflect IH practices.

OBJECTIVE

This study used a multi-phase pilot observational design to assess feasibility of incorporating eHL and EBM assessments into graduate coursework while adapting and validating the FEBM for an IH audience (FEBM-IH).

METHODS

Re-validation of the FEBM-IH began with a discipline-focused adaptation, which was reviewed by an expert panel. The FEBM-IH was then administered to IH students and faculty. Independently scored assessments determined inter-rater reliability, internal consistency, item discrimination, and item difficulty.

RESULTS

Outcome completion rates suggest the FEBM-IH and eHL assessment tools are feasible (>64% completion) to include in online courses, with 68.9% (102/148) eligible participants joining and 76.5% (78/102) completing all questions in all measures. The FEBM-IH demonstrated excellent assessor agreement (kappa = 0.97, p < 0.001), high internal consistency (α=0.799), and acceptable item discrimination (0.26-0.68).

CONCLUSIONS

Self-perceived eHL scores showed a 3-point increase in median score by course’s end, suggesting improvements in eHL. Tools were feasible to integrate; FEBM-IH maintains acceptable validity; and further exploration of the relationship between EBM and eHL is warranted.

CLINICALTRIAL

NA- Not a Clinical Trial
Environmentalism for Nature to Environmentalism for Profit
Authors: Widyana Maulida Rita , Salsabila Ayna Jamila , Yeuyanan Herry Pragus
Published: January 2024

This research discusses the discourse related to the mining of andesite stone for the construction of the Bener Dam in Purworejo, Central Java, as part of the National Strategic Project. The discourse constructed among actors is highly diverse. The dominant discourse is led by the government, which views the use of the forest for environmentalism for profit, while local residents see the forest as environmentalism for nature. Michel Foucault's discourse theory on the production of knowledge and power underscores the discourses brought forth by the government, the community, and NGOs. Meanwhile, Anja Nygren's concept of environmental discourse complements the various discourses that have emerged. The objective of this research is to observe the dynamics and discourse constructed by pro and contra actors regarding the construction of the Bener Dam. The research utilizes both primary and secondary data, with primary data obtained through direct interviews with sources such as Indonesian Forum for the Environment of Yogyakarta, Community Movement for Environmental Care in Wadas Village (GEMPADEWA), and Legal Aid Institute of Yogyakarta. The conclusion drawn from this research is that the dominant discourse constructed by the government can influence public opinion, especially through negotiations that lead to mutually beneficial agreements.
Prácticas de laboratorio que fortalecen la comprensión del campo eléctrico para estudiantes de ingeniería en Ciencias de la Tierra
Authors: López-Saucedo Felipe de Jesús , Batista-Rodríguez José Alberto , Almaguer- Carmenates Yuri , Gómez-González Juan Martín , Batista-Cruz Ramón Yosvanis
Published: January 2024

Este trabajo propone la aplicación de un ejercicio experimental para ayudar a los estudiantes de ingeniería en Ciencias de la Tierra a comprender los conceptos de campo eléctrico, potencial eléctrico, capacitancia y resistividad eléctrica. La metodología utilizada incluye el desarrollo de clases prácticas en el laboratorio y la aplicación de cuestionarios. El análisis de los resultados mostró que la mayoría de los estudiantes identifican la presencia del campo eléctrico en un material conductor o dieléctrico. Los estudiantes también reconocen que los ejercicios experimentales son didácticos y fortalecen su comprensión del campo eléctrico.
El hábitat de los hongos y su vulnerabilidad ante el cambio climático
Authors: Villegas-Gómez Fernanda Giovanna , López-Caballero Iriliana , Fonseca-Alvarez Rita
Published: January 2024

Los hongos son organismos con características únicas, las cuales no se presentan ni en plantas ni en animales, lo que los clasifica en un reino propio. Estos organismos tienen una alta distribución en la naturaleza tanto en el agua, el aire y el suelo. En este trabajo nos enfocaremos en la interacción que existe entre los hongos y el suelo, ya que son clave en el buen funcionamiento de los ecosistemas. Específicamente, abordamos la relación simbiótica entre las micorrizas y las raíces de las plantas a través del suelo que contribuyen activamente en los ciclos biogeoquímicos. Por su parte el cambio climático altera las condiciones atmosféricas y también las del suelo, lo que a su vez irrumpe el dinamismo ecológico y permite que se lleven a cabo estos procesos. De igual manera, la perturbación del suelo debido a agentes erosivos y actividades humanas ocasionan la pérdida del hábitat de millones de organismos que viven en esta capa superficial y que son esenciales para el funcionamiento óptimo de los ecosistemas terrestres.
Crayfish-Tracking Motion Vision to analyze the locomotor activity induced by changes in environmental lighting
Authors: Cedeño Moreno Rogelio , Morales Hernández Luis Alberto , Rodríguez-Sosa Leonardo , Cruz-Albarran Irving Armando , Calderón-Rosete Gabina
Published: January 2024

Crayfish show locomotor activity modulated by environmental lighting. Yet, little is known about different light spectra stimulation effects on the locomotor activity of crayfish, and laboratory instruments are generally limited to the study of a single animal. As such, this research describes the development and implementation of the Crayfish-Tracking Motion Vision (CTMV) system. Based on artificial vision, this system allowed for the observation and recording of locomotor activity in one to four Procambarus clarkii crayfish that were placed in individual compartments. The effect of blue or green monochromatic light stimulation was explored in two groups of dark-adapted crayfish (with a total of 15 adult crayfish). Light-emitting-diodes of blue or green spectra were applied for 5 min while locomotor activity in crayfish was monitored in a large container. Both light pulses caused similar reaction times of locomotor activity (2.9 ± 3.5 s). Meanwhile, the displacement score of “blue light” animals (2.1 ± 0.9 m) was lower than that of “green light” animals (2.8 ± 0.6 m). In contrast, velocity (1.1 ± 1 cm/s) and acceleration data (0 ± 0.8 cm/s2) of the two groups were similar. Finally, the locomotor activity decreased significantly when container size was decreased. These results showed that the CTMV system is appropriate for measuring the locomotor activities of multiple crayfish and suggested that both monochromatic lights induced different locomotor behavior in the crayfish. It has been postulated that this light-induced reflex activity, is caused by an interplay of the photoreceptor system output with a circadian system modulating light sensitivity and locomotor behavior in the crayfish,. It can be inferred that the CTMV system will benefit subsequent studies focused on light-induced reflex activity in crustaceans.
Optimal tracking in two-degree-of-freedom control systems: Coupled tank system
Authors: Teppa Pedro , FAGGIONI Miguel , GARCIA Germain
Published: January 2024

This article presents an optimal design of a two-degree-of-freedom (2-DoF) controller that will lead to zero asymptotic steady-state tracking error. The reference inputs are chosen from the set of steps, ramps, and other persistent signals used currently. The main idea is to transform the tracking 2-DoF problem into an equivalent state-space feedback-control synthesis one. Where, an internal model of the reference input is introduced. Then, through the linear quadratic regulator (LQR) technique, the desired performance objectives are addressed by minimizing a quadratic cost function. Finally, the computed state-feedback optimal gains are linked to the polynomials used within the 2-DoF formalism. The fundamental aspect of the design is that it only utilizes the measurable information of the plant provided by its inputs and outputs and take advantage of efficient state-space numerical algorithms. The proposed method is applied to a coupled-tank system, the results achieved confirm the effectiveness of the approach.
Effect of Health Education Classes Applying Flipped Learning
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Kim Yun-Su
Published: January 2024

Objectives The purpose of this study is to provide basic data for nursing education by identifying the effects of health education classes applied with flipped learning on learning motivation, learning-related self-direction, self-efficacy, critical thinking disposition, problem-solving ability, and learning satisfaction of nursing students.
Methods The study design is a one group pre-post design, and 151 sophomore nursing students who took health education courses at one university were selected from September 1st to December 6th, 2022. Data collection was conducted during the course of the class. For data analysis, descriptive statistics, paired t-test, Pearson's correlation, and stepwise regression were performed using the SPSS Statistics 22.0 program.
Results As a result, learning motivation (t=-3.40, p<.001), learning-related self-direction (t=-2.84, p<.005), self-efficacy (t=-2.98, p<.003) and learning satisfaction ( t=-3.08, p<.002) was significantly higher than the level before flipped learning, and problem-solving ability (t=-1.23, p=.218) and critical thinking disposition (t=-0.86, p=.390) had no significant difference. In addition, the factor influencing learning satisfaction was learning motiva-tion, and their explanatory power was 40.0% (F=100.95, p<.001).
Conclusions Through this study, it was confirmed that the health education class applying the flipped learning method is an effective teaching-learning method. A specific strategy for applying teaching and learning methods is required to increase learning satisfaction and strengthen learning competency for nursing students.
Research on attitudes toward and intention to use online counseling: Using the Unified Theory of Acceptance and Use of Technology
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Cho Yeji , Kim Eunha
Published: January 2024

Objectives The purpose of this study was to validate the Unified Theory of Acceptance and Use of Technology (UTAUT).
Methods For this, an online survey was conducted with a sample of 350 adults. For data analysis, an independent sample t-test, one-way ANOVA and structural equation model verification were conducted.
Results As a result, men scored higher on intention to use online counseling than women and participants on their 60s scored higher on both usefulness of and intention to use online counseling. In addition, participants who re-ceived face-to-face counseling and online counseling showed higher levels of intention to use online counseling compared to those who did not received any counseling. Finally, results supported the UTAUT.
Conclusions The results supported the UTAUT by revealing a casual chain in which perceived advantages of online counseling were positively related to utilization of online counseling through the perceived usefulness of online counseling. In contrast, perceived barriers of online counseling were negatively associated with utilization of on-line counseling through the perceived usefulness of online counseling.
Structural Relationships among Gains and Strains of Mothers’ Work-Family Balance, Parenting Stress, Chidren’s Psychological Characteristics, School Adjustment
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Choi Hyosik , Lee Seonyoung
Published: January 2024

Objectives The purpose of this study was to identify the structural relationship among the gains and strains of mothers’ work-parenting balance with children in the sixth grade of elementary school and to explore how its rela-tionship changes through the influences of parenting stress, elementary school students' self-esteem, and grit on school adjustment.
Methods A total of 769 pairs of mother-child data in the 13th wave of the Panel Study of Korea Children were ana-lyzed by using structural equation modeling. The measurement model verification was followed by the structural model verification, and the maximum likelihood method (ML) was used.
Results The results of this study are as follows. First, the strains between mothers' work-family balance had a positive effect on parental life stress and parental role stress, and the gains of mothers' work-family balance had a negative effect on parental role stress. Also, parental role stress has a negative effect on children's self-esteem and grit, mother’s life stress did not shown any relationship with self-esteem, grit, and school adjustment. In ad-dition, it was confirmed that childrens’ self-esteem had a positive effect on grit and school adjustment, and grit had a positive effect on school adjustment. Second, the strains in work-family balance has a negative effect on school adjustment through the multiple mediators of parental role stress, self-esteem, and grit, and the gains of work-family balance has a positive effect on school adjustment through the multiple mediators of parent role stress, self-esteem, and grit.
Conclusions This study suggests that the gains and strains of work-family balance affect the self-esteem, grit, and school adjustment of children through the mothers’ parental role stress. It implies that its important to reduce the parental role stress in order to help psychological stability and school adjustment of children.
Analysis of case studies on liberal arts writing education: Focusing on the case of communication course at a College
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, An Jung Hee
Published: January 2024

Objectives The purposes of this study were to improve writing education in colleges through analysiss of the case operation liberal arts writing cducation in T-College.
Methods For this purpose, I conducted a literature review on the general characteristics of liberal arts education in colleges and analyzed cases of writing education at T-College from 2016 to 2023. In particular, cases of curricu-lum reform in communication-related subjects were analyzed and presented, and the main characteristics that appeared in three periods of reform were analyzed. And I organized and analyzed how the writing contents has been changed. In addition to, the researcher's experience was additionally described T-college’s educational con-ditions and support systems in liberal arts curriculum.
Results As a result of analysis of writing educaion, the college has been providing communicational writing educa-tion as like a vocational skills. In addition to, addressing the problems lack of general support system, as like in-dependent liberal education support organization and overal consensus on the importance of liberal arts writing education were presented. It was suggested that minimal efforts are being made to meet national financial sup-port project evaluation standards.
Conclusions It was emphasized that writing education in colleges should be improved so that it develops the crit-ical thinking and problem-solving skills of learners who will live in the future. To this end, it is necessary to establish a writing education support system at colleges and consider writing education methods tailored to individual learners, such as an online writing feedback system. Through this, it was proposed to increase the efficiency and effectiveness of writing education in colleges.
The Effects of Children’s Creativity, Creative Teaching, and Classroom Environment
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Kim Jeong-Hee
Published: January 2024

Objectives The purposes of this study was to examine The Effects of children’s creativity, creative teaching, and classroom environment.
Methods This study aimed to investigate the influence of teaching practices and classroom environment on child-ren's creativity. The research focused on 200 children aged 4 and 5 attending kindergartens and preschools in the Gyeonggi Province, along with 100 lead teachers and 100 classrooms. Data collected were analyzed using SPSS 23.0, employing techniques such as frequency analysis, mean calculation, factor correlation, and regression analysis.
Results The results from these analyses are as follows. Firstly, statistically significant correlations were found be-tween creative teaching, children's creativity, and the classroom environment. Secondly, both creative teaching and the classroom environment exhibited statistically significant effects on children's creativity.
Conclusions Based on the results of this study, the importance of teaching practices for enhancing children's cre-ativity was highlighted. Suggestions were discussed regarding the direction of teaching practices and the oper-ation of classroom environments to promote children's creativity.
The Relationship Between Children's Perceived Parental Attachment and Self-Resilience: The mediating effect of autonomy
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Park Mi Jeong , Hwang Seon Jin
Published: January 2024

Objectives The purpose of this study is to examine the effects of children's perceived parental attachment on self-resilience and the effects of parental attachment on autonomy, and to explore the mediating role of autonomy in the relationship between children's perceived parental attachment and self-resilience.
Methods The study used data from the 12th Panel Study on Korean Children(2019), which included 725 boys (52.5%) and 689 girls (48.9%). For the analysis, SPSS25.0 and SPSS Process Macro3.0 were used to analyze the relationship between variables. Descriptive statistics, Pearson correlation analysis, and bootstrapping were used to test the significance of mediating effects.
Results The main findings based on the research questions were as follows First, parental attachment was sig-nificantly and positively related to both autonomy (r=.409, p<.001) and self-resilience (r=.404, p<.001). Second, autonomy was significantly and positively related to self-resilience (r=.396, p<.001). In contrast, the parental at-tachment subfactor, mother-alienation, was not significantly related to self-resilience. Third, we tested the me-diating effect of autonomy on the relationship between parental attachment and self-resilience. The results showed that parental attachment had a significant effect on autonomy and autonomy had a significant effect on self-resilience, suggesting that autonomy plays a mediating role between children's perceived parental attach-ment and self-resilience.
Conclusions Digital, climate change, and self-direction are the main themes of the 2022 curriculum. Personalized education is emphasized due to the declining school age population. The importance of student initiative and self-resilience is growing in order to proactively prepare for future changes and strengthen their utilization skills. This study suggests that it is important to strengthen parental attachment and autonomy in order to improve the self-resilience of school-aged children.
EFEITOS PSICOLÓGICOS DA PSILOCIBINA EM PORTADORES DE CÂNCER TERMINAL: Uma revisão de escopo
Authors: Silva Leonardo Hercilio Florêncio , Mata Júnia Aparecida Laia da , Stefanello Sabrina , Rocha Cristianne Maria Famer , Luiz Flavia Feron
Published: January 2024

Psilocybin is a natural substance with hallucinogenic properties that has recently been used in the field of health. It is an alkaloid that, when associated with psychotherapy, has shown benefits in the treatment of depression and anxiety. This study aims to analyze the current state of knowledge about the psychological effects of psilocybin in patients with terminal cancer. The method used was a scoping review guided by the guidelines of the Joanna Briggs Institute, following the PRISMA Extension for Scoping Reviews initiative. Data collection took place between August and December 2022, in the following databases: Medical Literature Analysis and Retrieval System Online, Cumulative Index to Nursing Allied Health Literature, Latin American and Caribbean Literature in Health Sciences, Scopus and Web of Science. A total of 340 articles were found, nine were selected and analyzed, elucidating the beneficial psychological effects of psilocybin in patients with terminal cancer. It found that they all point to the effectiveness of psilocybin in reducing symptomatic levels of depression and anxiety. Psilocybin is well tolerated by terminal cancer patients and has no significant adverse effects when administered in controlled settings. However, more scientific studies are needed with larger and more diverse samples.
Exploring the Dynamics of Maqashid Performance in Indonesian Islamic Banking
Authors: Nastiti Ari Sita
Published: January 2024

This study investigated the factors influencing the performance of Islamic banks in Indonesia by utilizing the Maqasid Sharia Index (MSI), specifically designed to assess Islamic bank performance in accordance with maqasid sharia principles. The sample sample was drawn from 57 data points gathered from 12 Islamic commercial banks registered with the Financial Services Authority (Otoritas Jasa Keuangan-OJK) from 2016-2020. Employing a quantitative approach, the study conducted data analysis through multiple linear regression. The results revealed that temporary shirkah funds and Islamic intellectual capital had a significant negative impact on MSI, while Islamic corporate governance exhibited a notably positive effect. This empirical investigation provides valuable insights into the determinants of Islamic bank performance in Indonesia, thereby contributing to the existing body of Islamic banking literature and offering practical implications for enhancing alignment with maqasid sharia through strategic resource optimization. The findings highlight the critical importance of reinforcing Islamic corporate governance and Islamic intellectual capital to enhance the performance of Islamic banks. Furthermore, expanding the scope of research to broader contexts could improve the generalizability of these findings.============================================================================================================ABSTRAK - Eksplorasi Dinamika Kinerja Perbankan Syariah Indonesia dengan Indeks Maqasid. Penelitian ini bertujuan untuk mengkaji determinan yang mempengaruhi kinerja perbankan syariah di Indonesia melalui pendekatan Maqasid Sharia Index (MSI). MSI khusus dikembangkan secara khusus untuk mengukur kinerja bank syariah agar lebih akurat karena mengakomodir prinsip-prinsip maqasid syariah. Sampel penelitian diambil dari 57 poin data dari 57 bank umum syariah yang terdaftar di Otoritas Jasa Keuangan (OJK) periode 2016-2020. Penelitian ini menggunakan pendekatan kuantitatif dimana data dianalisis melalui regresi linier berganda. Hasil kajian menunjukkan bahwa dana syirkah temporer dan modal intelektual syariah secara signifikan berpengaruh negatif terhadap MSI, sebaliknya tata kelola perusahaan syariah menunjukkan pengaruh positif yang signifikan. Hasil ini memberikan gambaran tentang determinan kinerja perbankan syariah di Indonesia, sehingga berkontribusi pada literatur perbankan syariah yang ada dan menawarkan implikasi praktis untuk meningkatkan kesesuaian dengan maqasid syariah melalui optimalisasi sumber daya strategis. Temuan ini menekankan pentingnya memperkuat tata kelola perusahaan syariah dan modal intelektual syariah untuk meningkatkan kinerja bank syariah. Untuk dapat meningkatkan generalisasi temuan ini, diperlukan kajian lebih lanjut dalam konteks yang lebih luas.
Measuring Muslim Welfare: A Falah-Based Index
Authors: Harahap Muhammad Arfan , Sukiman Sukiman , Harahap Isnaini
Published: January 2024

The concept of welfare remains a subject of ongoing debate, and the prevailing frameworks for assessing welfare need to be adapted to align with Islamic principles. This study delves into the concept of falah, a state of well-being rooted in Islamic values, to develop a 'falah welfare index' and analyze it within a Muslim community in Langkat Regency, Indonesia. Additionally, the study explores the variables that influence falah welfare. Employing a mixed-methods approach with an exploratory sequential design, this research qualitatively constructs a falah welfare index and quantitatively measures both community welfare levels and the impact of predictor variables on the criterion variable of falah welfare. A key finding of this study is the establishment of a falah welfare index comprising three categories: fakir (extreme poverty), miskin (poor), and falah (well-being). Moreover, the results reveal a positive influence of religiosity, Islamic work ethics, Islamic consumption ethics, Islamic investment patterns, and Islamic wealth management on falah welfare. The implications of this research offer a novel approach to measuring welfare within Muslim societies and solidify the concept of falah as a cornerstone of welfare evaluation from an Islamic economic perspective.==============================================================================================================ABSTRAK – Pengukuran Kesejahteraan Muslim: Analisis Indeks Berbasis Falah. Kesejahteraan masih menjadi fenomena yang terus diperdebatkan dan pengukuran kesejahteraan seorang Muslim perlu disesuaikan dengan karakteristik ke-Islaman. Tujuan penelitian ini untuk mengeksplorasi konsep falah dalam membangun ‘Indeks Kesejahteraan Falah’ dan menganalisis tingkat kesejahteraan masyarakat Muslim di Kabupaten Langkat, Sumatera Utara, Indonesia. Selain itu, penelitian ini juga menganalisis variabel yang mempengaruhi variabel kesejahteraan falah. Penelitian ini menggunakan metode campuran (mixed method) dengan desain exploratory sequential. Indeks kesejahteraan falah diinisiasi dengan metode kualitatif sementara metode kuantitatif digunakan untuk pengukuran terhadap tingkat kesejahteraan masyarakat dan pengujian pengaruh dari masing-masing variabel predictor terhadap variabel criterion. Analisis data dilakukan dengan pendekatan Structural Equation Modeling-Partial Least Square (SEM-PLS). Temuan utama penelitian ini adalah terbangunnya indeks kesejahteraan falah dengan tiga kategori tingkatan yaitu fakir, miskin dan falah. Kajian ini juga menunjukkan adanya pengaruh positif variabel religiositas, etika bekerja Islami, etika konsumsi Islami, pola investasi Islami dan pengelolaan harta Islami terhadap variabel Kesejahteraan Falah. Hasil ini berimplikasi dalam memberikan alternatif baru dalam pengukuran tingkat kesejahteraan masyarakat Muslim dan membuktikan soliditas konsep falah sebagai metode pengukur kesejahteraan dalam perspektif ekonomi Islam.
Saxifraga cataphracta (Saxifragaceae), a new species from Southwest China
Authors: Zhang Xinjian , Zhang Cheng , Kuai Xin-Yuan , Chen Jun-Tong , Deng Tao , Sun Hang
Published: January 2024

Saxifraga cataphracta, a new species of Saxifragaceae from Southwest
China, is described and illustrated. Morphological and molecular
evidence (matK, psbA-trnH, psaJ-rpl33) indicate that S. cataphracta
belongs to S. sect. Irregulares, and closely related to S. geifolia and
S. mengtzeana. The new species can be diagnosed by its leaf blade
abaxially with white or virescent interveinal streaks, involucre and
bracts conspicuous, capsule beaks winged when mature.
Revealing Euploca wightiana sp. nov., a new species of Heliotropiaceae from South India.
Authors: Antony Anna , P Javad , Antony Anphi
Published: January 2024

Euploca wightiana P. Javad & A. A. Ancy sp. nov., a new species of the
family Heliotropiaceae is described from Coimbatore district of South
India. Morphologically it is similar to Euploca marifolia but differs in
being perennial; erect woody stem with dense hirsute hairs; oblong
leaves with obtuse apex; inflorescence with distantly placed flowers;
long, cylindrical style with unifid, capitate stigma and densely hirsute
nutlets. The species remained misidentified in herbaria for long.
Detailed description, photo plates and distribution maps are provided.
Morphological differences with relevant species are discussed. The
status of the new species is provisionally assessed here as ‘endangered’
according to IUCN Red List Categories and Criteria.
Zeylleucapenoids A-H, Halimane-type and Labdane-type Diterpenoids with Anti-inflammatory Activity from Leucas zeylanica
Authors: Ting Zhao , Xuan Zhang , Xuhua Nong , Xueming Zhou , Ruru Chai , Xiaobao Li , Chen Guangying
Published: January 2024

Eight new diterpenoids (1-8) characterized as halimane-type and
labdane-type skeletons, and four known (9-12) compounds, were isolated
from Leucas zeylanica. Their structures were determined by comprehensive
spectroscopic analysis, X-ray crystal diffraction and computational
calculations. Compounds 1 and 2 represent structurally unique
6/6/6-fused tricyclic halimane-type diterpenoids. Compounds 8 and 12
exhibit nontoxic effects for zebrafish embryo, while they display
efficient reduction against NO production in a dose-dependent manner and
strongly suppress the secretion of LPS-induced TNF-α and IL-6 cytokines
in RAW264.7 macrophages. In addition, marked reductions of iNOS and
COX-2 in protein were observed. Molecular docking analysis indicated
that both 8 and 12 have high affinities with the target amino acid
residues on protein-binding sites, which may be a possible mechanism
contributing to the anti-inflammatory potential of these molecules.
Toll-like Receptors in Pathogenesis of Neurodegenerative Diseases and their Therapeutic Potential
Authors: Dabi Yosef Tsegaye , ͓ Abayomi Ajagbe , Degechisa Sisay
Published: January 2024

Toll-like receptors (TLRs) are a family of pattern-recognition receptors
(PRRs) triggered by pathogen-derived and tissue-damage-related ligands.
TLRs were previously believed to only be expressed in immune cells.
However, it is now confirmed that they are ubiquitously expressed in
cells within the body including neurons, astrocytes, and microglia of
the central nervous system (CNS). Activation of TLRs is capable of
inducing immunologic and inflammatory responses to injury or infection
of CNS. This response is self-limiting that usually resolves once the
infection has been eradicated or the tissue damage has been repaired.
However, the persistence of inflammation-inducing insults or a failure
in normal resolution mechanisms may result in overwhelming inflammation
which may induce neurodegeneration. This implies that TLRs may play a
role in mediating the link between inflammation and neurodegenerative
diseases namely Alzheimer’s disease (AD), Parkinson’s disease (PD), and
amyotrophic lateral sclerosis (ALS). So, new therapeutic approaches that
specifically target TLRs may be developed by better understanding TLR
expression mechanisms in the CNS and their connections to particular
neurodegenerative disorders. Therefore, this review paper discussed the
role of TLRs in neurodegenerative diseases.
Primulina Ganzhouensis (Gesneriaceae)，A New Species from Limestone Karst Area of Jiangxi Province, China
Authors: Chen Di , Zeng Nuo , Jin Zhi , Chen Zhi , Wu Xiao , Cai Wei , Zuo Zheng , XU GUO
Published: January 2024

Primulina ganzhouensis (Gesneriaceae) is described and illustrated here
as a new species. This new species resembles P. yangshanensis W.B.Xu &
B.Pan, but it is distinct from the latter by some obvious features in
leaf blade, bract, indumentum, corolla, filament, stigma and pistil.
Nuclear ribosomal internal transcribed spacer (ITS) region and plastid
trnL-F intronspacer (trnL-F) DNA sequence data from the new species and
its 188 relatives are used to determine the systematic position of the
new species within Primulina. Molecular evidence suggests that P.
ganzhouensis is strongly supported as a sister to a clade in which P.
yangshanensis is included. The conservation status of P. ganzhouensis is
assessed as ” Endangered” (EN) according to IUCN Red List categories
and criteria.