bluuebunny/crossref_metadata_2025 huggingface dataset:
Voice Pathologies Classification Using GMM And SVM Classifiers
Authors: Fethi Amara , Mohamed Fezari
Published: November 2021

In this paper we investigate the proprieties of automatic speaker recognition (ASR) to develop a system for voice pathologies detection, where the model does not correspond to a speaker but it corresponds to group of patients who shares the same diagnostic. One of essential part in this topic is the database (described later), the samples voices (healthy and pathological) are chosen from a German database which contains many diseases, spasmodic dysphonia is proposed for this study. This problematic can be solved by statistical pattern recognition techniques where we have proposed the mel frequency cepstral coefficients (MFCC) to be modeled first, with gaussian mixture model (GMM) massively used in ASR then, they are modeled with support vector machine (SVM). The obtained results are compared in order to evaluate the more preferment classifier. The performance of each method is evaluated in a term of the accuracy, sensitivity, specificity. The best performance is obtained with 12 coefficientsMFCC, energy and second derivate along SVM with a polynomial kernel function, the classification rate is 90% for normal class and 93% for pathological class.This work is developed under MATLAB
The Generalised Plug-in Algorithm for the Diffeomorphism Kernel Estimate
Authors: Troudi Molka , Ghorbel Faouzi
Published: November 2021

The optimal value of the smoothing parameter of the Kernel estimator can be obtained by the well known Plug-in algorithm. The optimality is realised in the sense of Mean Integrated Square Error (MISE). In this paper, we propose to generalise this algorithm to the case of the difficult problem of the estimation of a distribution which has a bounded support. The proposed algorithm consists in searching the optimal smoothing parameter by iterations from the expression of MISE of the kernel-diffeomorphism estimator. By some simulations applied to some distribution having a support bounded and semi bounded, we show that the support of the pdf estimator respects the one of the theoretical distribution. We also prove that the proposed method minimizes the Gibbs phenomenon.
Intelligent Pitch Controller Identification and Design
Authors: Torabi Amir , Ahari Amin Adine , Karsaz Ali , Kazemi Seyyed Hossin
Published: November 2021

This paper exhibits a comparative assessmentbased on time response specification performance between modern and classical controller for a pitch control system of an aircraft system. The dynamic modeling of pitch control system is considered on the design of an autopilot that controls the pitch angle It starts with a derivation of a suitable mathematical model to describe the dynamics of an aircraft. For getting close to actual conditionsthe white noise disturbance is applied to the system.In this paper it is assumed that the modelpitch control systemis not available. So using the identification system and Box-Jenkins model estimator we identify the pitch control system System’s identification is a procedure for accurately characterizing the dynamic response behavior of a complete aircraft, of a subsystem, or of an individual component from measureddata.To study the effectiveness of the controllers, the LQR Controller and PID Controller and fuzzy controller is developed for controlling the pitch angle of an aircraft system. Simulation results for the response of pitch controller are presented instep’s response. Finally, the performances of pitch control systems are investigated and analyzed based on common criteria of step’s response in order to identify which control strategy delivers better performance with respect to the desired pitch angle. It is found from simulation, that the fuzzy controller gives the best performance compared to PID and LQR controller.
The Effect of the PLISSIT Model on Sexual Functions: A Systematic Review
Authors: KIRICI Serap , EGE Emel
Published: November 2021

Aim: The aim of this systematic review is to determine the effects of the PLISSIT model (permission, limited, information, special suggestions, intensive therapy) on sexual functions.

Materials and Methods: The study was conducted by searching Google Scholar, Ulakbim, Web of Science, PubMed, and Science Direct electronic databases.

Results: It was observed within the scope of the systematic review that five of the studies assessed were conducted in Iran, and one of them was conducted in Turkey, and all of them were randomized controlled trials (RCT). The participant group was diverse. It was observed that the studies were conducted in quite various groups such as women who underwent hysterectomy, women with multiple sclerosis, HIV positive women, women who were in the postpartum period, pregnant women, and women with Type 2 diabetes.

Conclusion: Former studies showed that training and counseling programs basing on the PLISSIT model are effective in enhancing sexual functions.
BLOOD FLOW IN CORONARY ARTERY BIFURCATION CALCULATED BY TURBULENT FINITE ELEMENT MODEL
Authors:   University of Kragujevac, Institute for Information Technologies, Nikolić Aleksandar , Topalović Marko , Blagojević Milan , Simić Vladimir
Published: November 2021

Simulation of blood flow in this paper is analyzed using two-equation turbulent finite element model that can calculate values in the viscous sublayer. Implicit integration of the equations is used for determining the fluid velocity, fluid pressure, turbulence, kinetic energy, and dissipation of turbulent kinetic energy. These values are calculated in the finite element nodes for each step of incremental- iterative procedure. Developed turbulent finite element model, with the customized generation of finite element meshes, is used for calculating complex blood flow problems. Analysis of results showed that a cardiologist can use proposed tools and methods for investigating the hemodynamic conditions inside bifurcation of arteries.
A META-HEURISTIC MULTI-OBJECTIVE APPROACH TO THE MODEL SELECTION OF CONVOLUTION NEURAL NETWORKS FOR URINARY BLADDER CANCER DIAGNOSIS
Authors:   University of Rijeka, Faculty of Engineering, Lorencin Ivan , Smolić Klara , Markić Dean , Španjol Josip ,   University of Rijeka, Faculty of Medicine
Published: November 2021

Bladder cancer is one of the most common malignancies of the urinary tract. It is characterized by high metastatic potential and a high recurrence rate, which significantly complicates diagnosis and treatment. In order to increase the accuracy of the diagnostic procedure, algorithms based on artificial intelligence are introduced. This paper presents the principle of selection of convolutional neural network (CNN) models based on a multi-objective approach that maximizes classification and generalization performance. Model selection is performed on two standard CNN architectures, AlexNet and VGG-16. Classification performances are measured by using ROC analysis and the resulting AUC value. On the other hand, generalization performances are evaluated by using a 5-fold cross-validation procedure. By using these two metrics, a multi-objective fitness function, used in meta-heuristic algorithms, is designed. The multi-objective search was performed using a Genetic algorithm (GA) and a Discrete Particle Swarm (D-PS) algorithm. From obtained results, it can be noticed that such an approach has resulted in CNN models that are defined with high classification and generalization performances. When a GA-based approach is used, fitness values up to 0.97 are achieved. On the other hand, by using the D-PS approach, fitness values up to 0.99 are achieved pointing towards the conclusion that such an approach has provided models with higher classification and generalization performances.
THE SIMULATION MODELLING METHODS FOR ORGANIZATION OF THE ONCOLOGY PATIENTS ROUTING
Authors:   Peoples Friendship University of Russia, Zuenkova Julya , Kicha Dmitry
Published: November 2021

Patient routing is a key tool for ensuring the availability and quality of cancer care, ensuring early detection of pathology and timely treatment. Mathematical and simulation modeling methods allow to predict the bottlenecks of patient flows and plan the optimal distribution of healthcare resources. Goal to optimize patients’ pathways for oncology care using the simulation modelling methods. Materials and methods Patient routing was presented in the logic of discrete events, the average resource utilization, the patient’s stay time were described, the bottlenecks of the system were determined. Simulation modeling methods were used to build the optimal organization of oncology care services in the region. Results The average waiting time at the pre-hospital stage was 10 days, the average hospitalization time for X-ray therapy was 24 bed days, the throughput of the X-ray therapy room was 6 patients per week, the average duration of the X-ray therapy session per patient was 10 minutes. With the help of simulation modeling methods, a multimodal system of oncodermatology care was created and put into practice, which allowed to reduce the patient’s waiting time for treatment to 0.7 days, increasing the throughput of the entire system.
ELECTROSPUN GELATIN NANOFIBROUS SCAFFOLDS – APPLICATIONS IN TISSUE ENGINEERING
Authors:   University of Kragujevac, Institute for Information Technologies, Virijević Katarina , Grujić Jelena , Jovanović Milena , Kastratović Nikolina , Mirić Ana , Nikolić Dalibor , Živanović Marko , Filipović Nenad
Published: November 2021

Electrospinning is highly used technique in the tissue engineering field, particularly in biomedical application [1]. The constricted concepts of this process are based on generate nonwoven nanofibers. The method involves high voltage electricity which is applied to the liquid solution and a collector, which lets the solution force out from a nozzle forming a jet. The jet formed fibers under influence of electrostatic forces concentrated and deposited these on the collector. Main objective of this study was to fabricate gelatin scaffolds with micro/nano-scale for successful wound dressing. Gelatin can mimic the chemical composition, physical structure and structure of the native skin extracellular matrix (ECM). However, the first and main principle in this study is the optimization of parameters of the electrospinning process. The used parameters have a crucial role in obtaining suitable fibers for further cell seeding and cell growth in vitro. With the use of series of various biocompatible polymers and solvents, solutions were tested in various electrospinning settings in order to produce microscale fibers. The scaffolds were analysed with scanning electron microscope images for fiber diameter measurement.
USE OF CONVOLUTIONAL NEURAL NETWORKS FOR X-RAY IMAGE ORIENTATION DETERMINATION
Authors:   University of Rijeka, Faculty of Engineering Rijeka, Baressi Šegota Sandi , Lysdahlgaard Simon , Hess Søren , Antulov Ronald
Published: November 2021

The fact that Artificial Intelligence (AI) based algorithms exhibit a high performance on image classification tasks has been shown many times. Still, certain issues exist with the application of machine learning (ML) artificial neural network (ANN) algorithms. The best known is the need for a large amount of statistically varied data, which can be addressed with expanded collection or data augmentation. Other issues are also present. Convolutional neural networks (CNNs) show extremely high performance on image-shaped data. Despite their performance, CNNs exhibit a large issue which is the sensitivity to image orientation. Previous research shows that varying the orientation of images may greatly lower the performance of the trained CNN. This is especially problematic in certain applications, such as X-ray radiography, an example of which is presented here. Previous research shows that the performance of CNNs is higher when used on images in a single orientation (left or right), as opposed to the combination of both. This means that the data needs to be differentiated before it enters the classification model. In this paper, the CNN-based model for differentiation between left and right-oriented images is presented. Multiple CNNs are trained and tested, with the highest performing being the VGG16 architecture which achieved an Accuracy of 0.99 (+/- 0.01), and an AUC of 0.98 (+/- 0.01). These results show that CNNs can be used to address the issue of orientation sensitivity by splitting the data in advance of being used in classification models.
Virtual Education in English Literature Courses during Pandemic COVID-19: Merits and Demerits, and Needs
Authors: Mehrpouyan Azadeh , Zakeri Elahesadat
Published: November 2021

Distance education and e-learning became widespread and necessary with the miracle of the internet and its increasing influence among the individuals much within the days of a pandemic outbreak of COVID-19. Many universities, institutions, and learners encourage using e-learning and begin growing in this field. This paper examines the merits and demerits of distance and online education teaching for English literature educators and students. Technology and increasing demand for education, traditional strategies do not meet the growing requirements of academic communities and virtual education and e-learning with all their benefits and drawbacks attempt to meet these needs. This paper investigates e-teaching and e-learning infrastructure, needs, benefits, and limitations, in addition to opportunities and challenges of online education within the days of the coronavirus occurrence. The research method of the current study was conducted through a library study along with empirical study and descriptive analysis. New challenges of English literature educators and students in pandemic COVID-19 were identified and new approaches to remove the constraints are suggested. The results confirm online education is a constant educational need not limited to pandemic period and have to be compelled to develop productivity and creativity in learning with the appearance of recent technologies such as computers, the web, and social networks. These skills development can assist educators to find solutions for these difficulties in various areas of educational, cultural, and social issues. Blended learning can contribute to post-pandemic English literature classes and sustainable higher education.
Training project as an autonomous learning strategy using a virtual platform for the development of competences
Authors: Zamora René Rodríguez , Núñez Leonor Antonia Espinoza
Published: November 2021

En esta propuesta se presenta el uso de las nuevas tecnologías como una herramienta de apoyo educativo y como una práctica generada a partir del acercamiento cognitivo y afectivo del estudiante con los contenidos de la asignatura,  así mismo tiene la doble intención de iniciar un conjunto de prácticas educativas, mediante la estrategia de proyecto formativo, sobre la base del aprendizaje autónomo, colaborativo y  orientado en la investigación, lo que le permite conocer el fenómeno psicosocial estudiado en sus diversos contextos de significación. Esta propuesta se circunscribe en un modelo constructivista que ubica al sujeto que aprende como el principal actor que llega a controlar su propio proceso mediante el establecimiento de un plan de acción que consensa de manera colectiva. Por otra parte se ubica dentro del enfoque por competencias que define el marco de la reforma educativa, contenida en el enfoque por competencias, estableciendo las áreas a desarrollar. En este sentido, se desarrollan las competencias integrando el saber, el saber hacer y el saber ser. Se pretende con esta estrategia atender el desarrollo de competencias mediante la identificación de problemas y la aplicación del proceso investigativo, a través de la metodología de proyectos desarrollando aptitudes y actitudes para el trabajo colaborativo y la incorporación de la tecnologías para un mejor desenvolvimiento de la práctica educativa.
Avaliação laboratorial de pacientes com osteoporose
Authors: Dreyer Patricia , Vieira Jose Gilberto
Published: November 2021

O hipoestrogenismo no período da menopausa, a perda óssea involucional, fatores genéticos e menor pico de massa óssea são responsáveis pela maioria dos casos de osteoporose. No entanto, uma avaliação laboratorial osteometabólica deve ser realizada em todo paciente que procura avaliação médica por redução da densidade mineral óssea (DMO) ou pela presença de fratura por fragilidade, já que causas secundárias identificáveis estão presentes em parte substancial desses indivíduos(1,  2). Uma anamnese abrangente associada ao exame clínico cuidadoso constitui o principal instrumento para guiar a escolha dos exames laboratoriais.
A triagem inicial sugerida inclui as seguintes avaliações laboratoriais:
- Hemograma: a presença de anemia pode estar relacionada ou a doença celíaca ou a mieloma múltiplo.
- Cálcio total ou ionizado: hipercalcemia secundária a hiperparatiroidismo primário ou neoplasias. Níveis de cálcio no limite inferior da normalidade ou hipocalcemia podem sugerir hipovitaminose D ou doenças disabsortivas. A disponibilidade de metodologias automatizadas com alta precisão faz que as vantagens da medida do cálcio ionizado se limitem a indicações pontuais (acidose metabólica, hipoproteinemia importante).
- Calciúria de 24 h: o aumento da excreção urinária de cálcio é definido por valores acima de 250 mg/dia para mulheres ou acima de 300 mg/dia para homens numa dieta normal em cálcio. Aumentos significativos podem estar relacionados a condições de hipercalcemia (hiperparatiroidismo primário) ou a normocalcemia (hipercalciúria idiopática por defeito tubular renal). A relação cálcio/creatinina em amostra de urina isolada também pode ser utilizada. Valores acima de 0,20 sugerem hipercalciúria. Hipocalciúria (menos 100mg/dia) sugere hipovitaminose D ou baixo aporte de cálcio na dieta, exceto em pacientes em uso de diuréticos tiazídicos, que aumentam a reabsorção tubular de cálcio e reduzem a calciúria secundariamente.
- Creatinina: elevação da creatinina indica insuficiência renal, pode acompanhar o mieloma múltiplo, além da osteodistrofia óssea do renal crônico que pode se apresentar como osteoporose.
- TSH: o hipertiroidismo, ainda que subclínico, pode estar associado à perda óssea e a maior risco de fraturas,. especialmente em mulheres na pós-menopausa(3).
- Dosagem de 25OH vitamina D: a avaliação do status de vitamina D sérica é feita pela dosagem de 25OH vitamina D circulante. Esses níveis refletem melhor as reservas corporais. Esta dosagem deve ser realizada sempre que possível já que a hipovitaminose pode estar presente mesmo com cálcio, PTH e calciúria normais(4,  5). A dosagem do metabólito ativo, a 1,25(OH)2 vitamina D, deve ser limitada às raras circunstâncias onde um problema de síntese excessiva seja a causa de hipercalcemia, ou um déficit de síntese seja a razão de hipocalcemia.
Osteoporose masculina
Authors: Zerbini Cristiano A. F. , Pippa Maria Guadalupe B.
Published: November 2021

Osteoporose, uma doença metabólica caracterizada por baixa massa óssea, deterioração da microarquitetura do tecido ósseo e aumento da suscetibilidade a fraturas, é comumente vista como um problema de saúde feminino. Essa visão tem fundamentos: as mulheres têm densidade mineral óssea menor que a dos homens, tem vida mais longa que os homens e perdem massa óssea mais rapidamente que os homens, principalmente após a menopausa, devido à diminuição acentuada dos níveis séricos de estrógeno. Entretanto, nos últimos 15 anos a osteoporose no homem tem sido reconhecida como um problema de saúde pública devido à ocorrência cada vez maior de fraturas por fragilidade. Cerca de 30% de todas as fraturas de quadril ocorrem em homens (1).
Estudos recentes mostram que a probabilidade de ocorrer uma fratura por fragilidade do quadril, vértebra ou punho em homens caucasianos após os cinquenta anos, pelo resto de suas vidas, situa-se em torno de 13%, sendo 40% nas mulheres (2). Os homens apresentam perda de massa óssea e fraturas tardiamente em relação às mulheres. No Brasil, publicou-se estudo relativo à massa óssea em homens com idade de 50 anos ou mais demonstrando que a perda de massa óssea no colo femoral foi significativamente maior com idade de 70 a 79 anos (3). Após os 50 anos de idade as fraturas por osteoporose são duas a três vezes mais comuns em mulheres que em homens. Com o avançar da idade as fraturas de quadril se tornam mais frequentes, aproximando a incidência entre os dois sexos. Dos 85 aos 89 anos essas fraturas compõem cerca de 33% de todas as fraturas por fragilidade no homem e 36% nas mulheres.
Embora homens mais idosos tenham maior risco de fratura, cerca de metade das fraturas de quadril ocorrem antes dos 80 anos de idade (4). A expectativa de vida está aumentando para ambos os sexos no Brasil e em todo o mundo, porém em uma velocidade maior para homens que para mulheres. Dados recentes mostram que o Brasil tem 11.422 idosos com mais de cem anos de idade. Desse total, 7.950 são mulheres e 3.472 são homens (5). Em 2000, estimou-se a ocorrência de 424 mil fraturas de quadril em homens em todo mundo e para 2025 projeta-se a ocorrência de 800 mil, o que representa um incremento de 89% em 25 anos (1). A morbidade e a mortalidade associadas a fraturas de quadril e vértebra parecem ser maiores no homem que na mulher, o que pode estar associado à maior presença de comorbidades e menor expectativa de vida no homem. Mais homens morrem após o primeiro ano da fratura de quadril que mulheres (6).
Hill Slope Failure During The Development Of Infrastructure Projects In Himalaya: Case Study of Udhampur- Ramban National Highway, Jammu and Kashmir, India
Authors: Pandey Vinay Kumar
Published: November 2021

Himalaya is youngest tectonic Active Mountain and northern boundary of India. Various infrastructure projects are under develop in Himalayan region for the better connectivity of peoples and national security of border line.  Widening of 295 km National Highway-44 in Jammu and Kashmir is an important developmental project. The highway passes through Outer Himalayan and Higher Himalayan sequences of rocks and is frequently affected by landslides at various places. The paper deals with 43 km Udhampur-Chenani and Nashri- Ramban section of the highway within sedimentary and metamorphic rock sequence. The area is prone to landslides on account of fragile geological, topographic and hydrological conditions. The study area has high rainfall intensity and numerous old landslides zones. During the project feasibility stage, project authority has identified the landslide prone area and suggested precautionary measures but during the construction work various unpredicted landslide and ground sinking events happened which given trouble in project construction cost and project completion time. In this paper, the challenges faced due to landslide and ground failure as failure of old slide adjutant to road construction, agriculture and residential ground failure at higher altitude due to road construction, collapse of high tension towers in cut slopes; its impact on construction activities; are discussed with  mitigation measures for unidentified landslide related challenges.
Análisis estructural estático y modal del ala del Sistema Aéreo no tripulado “Tlapixki” para monitoreo volcánico en México
Authors: Bejarano Eduardo Antonio Medina , Flores José Félix Vázquez , Ochoa Miguel Angel Rosales
Published: November 2021

El presente trabajo consiste en el análisis Estático y modal del ala del UAS del proyecto “Tlapixki” [1] [2] que se está desarrollando en la ESIME Ticoman del Instituto Politécnico Nacional, cuya misión es apoyar al Centro Nacional de Prevención de Desastres (CENAPRED) en el monitoreo volcánico mediante toma de fotografía, video y toma de muestras de ceniza. El material utilizado en la estructura es el aluminio 2024-T3. Para el Análisis estructural se calcularon las condiciones de crucero, ascenso y descenso utilizando un paquete de elementos finitos obteniendo el estado de esfuerzos, deformaciones y sus modos de vibración, apegados a las indicaciones dadas por el Apéndice A del FAR23. Con respecto a los resultados obtenidos de la investigación, muestran que la estructura del ala analizada es capaz de soportar las cargas estructurales además de cumplir con el factor de seguridad establecido en el FAR.
A Comprehensive Ayurvedic Review on Arma and its Management
Authors: Pankaj Kundal  , Kamble Pallavi Namdev
Published: November 2021

Arma is a disease of Shukla mandala. In Ayurveda it has been described under Shuklagta Sadhya Vyadhi. This is a disease in which, a wing like triangular fibro-vascular layer or structure gradually encroaching towards the Krisna Mandala from either Kaneenika (Inner canthus) or Apanga Sandhi (outer canthus) of the eye. If this layer invades the cornea (Krisna Mandala) which is transparent in nature causes damage of the transparency of that part of cornea and thereby may cause disturbance in vision. On the basis of signs and symptoms described by the modern medical science, the disease ‘Arma’ can be correlated with Pterygium. This article gives a brief description about Nidanpanchak described in Samhita related to Arma in which Nidan, Purvroop, Roopa, and Sampapti ghatak described in detail. Along with Nidanpanchak detail description of types of Arma, Sadhya-asadhyatv, Chikitsa vivechan, Updrav, and Pathya-pathya mentioned in Samhita. The first and foremost method of treatment of Arma is Chedana Karma. However in the initial stage it can be treated with Lekhana Anjanas. Lekhan and Chedan is the main line of treatment of Arma. This article also defines the surgical procedure of Arma.
Management of Computer Vision Syndrome with Saindhava Jala Seka and Triphala Ghritapana - A Case Study
Authors: Borkar Manasi R  , Kotangale Sumedha Y  , Kotangale Yogesh T
Published: November 2021

Computer vision syndrome (CVS) is a symptom complex in which symptoms develop due to long screening time and improper postures while using computers. Ayurveda has mentioned Shushkakshipaka under Sarvagat Netra Roga. The symptoms of CVS and Shushkakshipaka when corelated, it denotes imbalance of Vata and Pitta Dosha. These vitiated Doshas carried by Siras to the eyes. When Doshas accumulated in eye the condition develops, called as Shushkakshipaka. Over use of Internet, Computers, Electronic devices increasing the risk factors about maintaining the normal vision. For the management of the CVS case, the Saindhava Jala Seka and Abhyantara Triphala Ghritapana is chosen from Sushrut Samhita. Triphala Ghrita is beneficial for complete maintenance of physiology of eye. The Guna Karma of Saindhava and Triphala Ghrita are Vata-Pitta Shamaka and both having Chakshushya properties. The main purpose for this study is to find safe and effective treatment without untoward effect in the management of CVS along with respective ergonomics advice. The required clinical tests done to observe the effectiveness of the combination of local and systemic treatment. The dryness in the eyes and associated symptoms can be resolved with the local treatment like Seka. Both the treatment modalities in combination have potential to give local and systemic relief improving the symptoms of CVS.
Psychological Understanding of Hypertension- Ayurvedic Perspective
Authors: M. Jithesh  , PU Sreeram  , P. Gowrisankar  , K. Asha Karunakaran  , S. Aswathy
Published: November 2021

Hypertension is the condition where blood pressure is elevated chronically. It has multiple factors such as genetic, environmental and life style. The Stress which is usually having a role in the scenario, usually is left unaddressed and the condition is managed only with the anti-hypertensives. Discussion of hypertension in the perspective of Ayurveda is a debatable area till now. Hṛdaya considered to be the root place of hypertension, has its origin from Rakta and Kapha in the normal state of development. Being abode for consciousness, senses, mind, soul etc. it is to be taken as a conglomeration of somatic, psychic as well as spiritual entities. Śṛama, Mōha, Mūṛchā which is exhibited in the circumstances of alteration of ojus such as Ōjakṣaya/ Ōjōvyāpath, can be observed in elevated blood pressure situations. Tridōṣa also contributes a major role in the development of hypertension through their dysfunctions. While considering the Nidāna paṉcaka of stress associated hypertension, negative emotions such as fear, anxiety, anger and excessive thoughts are always going in parallel to the unhealthy dietary habits and sedentary life style. A multidisciplinary approach may be ideal and quite useful in such situations. Ayurvedic principles along with the practices of yoga can improve positive health in this intricate scenario.
A Clinical Study to Evaluate the Effect of Amrita Guggulu and Guduchi Kwath in the Management of Vatarakta w.s.r. to Gout
Authors: Vijay Chaudhary  , Ankita Agrawal
Published: November 2021

In present time, lifestyle disorders are rapidly rising in our society. Over consumption of food, alcohol and fructose sweetened soft drinks in combination with a sedentary lifestyle has resulted in increased prevalence of visceral obesity, metabolic syndrome and gout in all socioeconomic groups of society including the lower socioeconomic status. Gout is one of the major life style disorders. The clinical manifestation and textual references of gout may be attributed with 'Vatarakta', also known as Vatashonita. Vata and Rakta are the Dosha and Dushya respectively which are primarily involved in the pathology of Vatarakta. Virudhaahar and Vihara aggravate Vata dosha and Rakta dhatu. Provocated Vata gets Aavrut with vitiated Rakta dhatu leading to the beginning of pathophysiological cascade of Vatarakta. The patients for this study were diagnosed based on Ayurvedic and modern parameters. Clinical signs and symptoms described in classical texts were considered for the diagnosis of Vatarakta, whereas serum uric acid was considered as investigation based diagnostic tool. Total 15 patients were registered in trial. The selected patients were given the trial drug i.e., Amrita guggulu one gram and Guduchi kwath 50ml twice a day with plain water after food. Out of 15 registered patients, 1 dropout from the trial, 4 patients (28.57%) showed marked improvement, 7 patients i.e., 50% showed moderate improvement and 3 patients 21.43% showed mild improvement. None of patient in present clinical trial remained unimproved or deteriorated during the clinical trials. In the present study, none of the patient reported any adverse effect to the trial drug during study and follow up period.
Enlightening the Brahmamudra- As Per Yogmimansa in Management of Manyastambh w.s.r. to Cervical Spondylosis
Authors: Farhatunnisa Syed A.A  , Manore Deepali  , Khatun Hazera
Published: November 2021

Cervical spondylosis (CS) is a degenerative and age-related condition affecting neck joints. It is also known as cervical osteoporosis. This is usually found in men and women at the age of 40 years or above.
The aim of present study to reduces the symptoms and increases in functional activities of elderly patients with spondylosis before and after Bramhamudra.(Yoga posture)
In this clinical study, total 30 patients were enrolled. All patients were treated on Brahmamudra fallowed by micro exercise and diet on the day of enrollment and after 30 day with the schedule as 0th 7th 15th 30th day fallow up. There is no drop out.
Clinical assessment done on day 1st and 30th day of fallow up, shows results of improvement in all the assessment criteria in neck region. Neck pain and the symptoms was assessed examination (X-ray, MRI) by symptomatic score used by VAS (Visual analog scale), physical examination through ROM (range of movement), cervical disability score questionnaire, radiological and examination by pathological test (uric acid, ESR, RA factor, BMD in the patient willing to do) on the day of enrollment. Then after fallow up the neck pain was examination by symptomatic score used by VAS, physical examination through ROM, cervical disability score questionnaire (radiological and examination by pathological test if required).
In conclusion, a combination of Yoga with diet control is found to be effective in reducing pain, and facilitating improvement in functional status of elderly people suffering from CS.
Ayurvedic Management of Severe Dry Eye Syndrome & Complications: A Case Study
Authors: Preeti Pahwa  , Ashu Vinaik  , Priya Patel  , Jasmine Kaur
Published: November 2021

Dry eye syndrome (DES) is a common condition that causes pain and can lead to vision problems. Modern living has given rise to a massive increase in the incidence of vision threatening dry eye disease, around 10-30% of population living in industrialized countries suffer from dry eye syndrome (DES). According to Second International Dry Eye Workshop (DEWS II) in 2017 offered dry eye as it is a multifactorial ocular surface disorder defined by a loss of tear film homeostasis and ocular symptoms, in which tear film instability and hyperosmolarity, as well as ocular surface inflammation and injury, play a part in the etiology. If it is not controlled with in time it can lead to corneal blindness. Ayurveda proposes a comprehensive systemic & topical strategy in the treatment of dry eye syndrome, in contrast to the available modern medical treatment. In this publication, a case study of a Shushkakshipaka with many complications who was treated with dynamic Ayurvedic treatments & after continuous efforts patient got very significant results is being discussed here.
A Comprehensive Understanding of Shukrala Karma in Male Infertility
Authors: Nagendra Chary.M  , Lalitha B.R  , T.Anil Kumar
Published: November 2021

Male reproductive health depends upon the normal structures and functions of Shukrava srotas. Shukra is composed of both sperm and semen and considered one of the important factors for fertilization. It is stated as Phalavat shukra. Preceptors of Ayurveda have described eight types of Shukra dosha and their treatments. Low sperm count, decrease sperm motility, abnormal sperm morphology, ejaculatory problems, sexual dysfunctions, environmental exposures (radiation, pollution, and stress etc), lifestyle habits (smoking, alcohol, recreational drugs etc), varicocele, hormonal imbalances, DNA damage, and reactive oxygen species (ROS) etc are causative factors for Male infertility. Thousands of years back, ancient system of medicine has mentioned the word Purusha vandya (male infertility) and different pharmacological activities, medicinal formulas, therapies to treat sperm disorders, semen impairments, and sexual dysfunctions.

Vajeekarana is one of the special branches of Astanga Ayurveda which maintains the fertility and management of male infertility. Shukrala, Shukra janana, Shukra shodhana, Shukra rechaka, Shukra pravataka and Shukra sthambhaka etc., are the pharmacological activities mentioned to treat Shukradoshas. Shukrala karma mainly composed of Shukra vrudhikara and Shukra srutikara means which enhances the Shukra (semen and sperm) quantitatively and qualitatively and facilitates its ejaculation. Therefore, an attempt has been made to establish the concept of Shukrala karma and its therapeutic applicability in the management of male infertility.
The importance of HbA1C test in prediabetes with special reference to Purvarupavastha of Prameha-A literary review
Authors: Archana R.Gharge  , Rajiv Mundane
Published: November 2021

Diabetes mellitus is a metabolic disorder causing hyperglycaemia with defect in metabolism of carbohydrates, fats, and proteins due to defect in insulin secretion, or its utilization or both. Prediabetes is a condition in which the blood glucose levels do not meet the criteria for diabetes or too high to be considered normal (ADA). It is an early stage of DM. So it is important to diagnose Diabetes Mellitus type 2 in the previous stage that is prediabetes. It is already in practice to diagnose it with laboratory blood tests. But additionally, we can also take help of Prameha purvarupas as premonitory symptoms in patients prediabetes. HbA1C is a useful parameter to diagnose prediabetes. There is mild or no symptoms mentioned for prediabetes. Purvarupas of Prameha mentioned in Ayurvedic samhitas can be useful to know early stage of Diabetes mellitus type 2, clinically. The purpose of this article is to highlight the importance of Purvarupa of Prameha to diagnose prediabetes. So, the need of hour is to focus on screening and diagnosing pre-Diabetes earlier, by spreading knowledge and awareness among society which will play a key role to reduce the conversion of pre-diabetes to diabetes mellitus.
A Comparative Clinical Study to Evaluate the Efficacy of Guduchyadi Kashaya and Rajrukshadipachana Kashaya in the Management of Eka Kushta w.s.r to Psoriasis
Authors: Moulika Markonda  , Sowmya S.B
Published: November 2021

In Ayurveda, all skin diseases have been described under the umbrella of Kushtha. Ekakusta is considered as the most commonest skin disease that can affect an individual. Acharya Charak has described the involvement of Vata-Kapha in Eka Kushtha. In the present study Eka kushtha is compared with psoriasis due to resemblance of signs symptoms and causative factors with it. Psoriasis is a papulosquamous disorder of the skin, characterized by sharply defined erythematosquamous lesions this illness exhibits a prompt response if treated carefully, left it may run a very chronic course extending into larger area of the body.

Ayurveda focuses more on curative management than palliative management. The drug used in the treatment of Ayurveda does not have complications like modern treatment. Repeated Sodhana prevent the recurrence of the disease. Similarly various preparations have been advocated for the management of Psoriasis.

The drugs used in this study are Guduchyadi Kashaya & Rajrukshadi Pachana Kashaya. Both the Kashayas are said to be effective in skin diseases. As per Yogaratnakara, Guduchyadhi Kwath has been mentioned as one of the drug having curative effect on all types of Kustha. Hence for present study the orally Guduchyadi Kwath is taken for EkaKustha treatment. The drugs in Guduchyadi Kwatha are Kusthaghana, Twachya, Swedal, Tridosh shamaka, as well as with Rasayan properties, which is beneficial to break down the pathogenesis of disease. As per Gadanigraha, as mentioned in Kayachikitsakhanda, Rajvrukshadipachana Kashaya is mentioned for the treatment of Ekakushtha. Ingredients in Rajvrukshadi Pachana Kashaya reduce Kapha dosha and most of them act on the skin. Kwatha dravyas are Rasadushtihara, Kaphapittahara, Deepana, Twachya, and also having antibacterial, antimicrobial, antiparasitic and anti-inflammatory properties, Hence, it is helpful for clearing the skin infections.
Tüketicilerin Çevreye Duyarlı İşletmelere ve Ürünlerine Karşı Bakış Açıları
Authors: ÇEVİK Osman , GÜLER Tuba
Published: November 2021

İşletmeler varlıklarını sürdürebilmek için faaliyette bulundukları alanlarla ilgili çevrelerini olumlu veya olumsuz yönde etkilerken kendileri de çevrelerinden etkilenmektedirler. Bu etkileşim, birçok işletmenin çevreye bakışını değiştirerek çevre bilincine sahip olmalarını ve çevre stratejilerini işletme stratejileri ile birleştirmelerine neden olmuştur. Böylece zaman içerisinde çevreye duyarlı tüketicilerin istek ve ihtiyaçlarını en iyi şekilde karşılayabilmek için çevreye en az zarar veren işletme stratejileri kullanılmaya başlanılmıştır. Buradan hareketle tüketicilerin çevreye duyarlı işletmelere ve ürünlerine karşı bakış açılarını belirlemeyi amaçlayan bu çalışmada Karaman il merkezinde yaşayan ve kolayda örnekleme yöntemiyle seçilen 350 katılımcıya anket uygulanmıştır. Elde edilen veriler frekans ve yüzde tabloları, Ki Kare, Mann Whitney U ve Kruskal Wallis testleri ile analiz edilmiştir. Analizler sonucunda, ‘Çevreye Duyarlı Yönetim’ kavramı tüketicilerin büyük çoğunluğu tarafından bilmesine rağmen ‘Sürdürülebilirlik’ kavramının daha az bilindiği gözlemlenmiştir. Yine katılımcıların çevreye zararlı olduğunu öğrendikleri ürünleri almaya devam etmedikleri, çevre dostu ürün satın alarak çevrenin korunmasına katkıda bulunduklarına inandıkları ve çevre sorunlarının çözümü için yapılan yatırımların işletmeler açısından lüks olmadığını düşündükleri, ancak ürün satın almaya karar verirken çevreye dost malzemeden üretilmiş olmasına pek dikkat etmedikleri görülmüştür. Genel olarak katılımcıların, işletmelerin çevre sorunlarına yeterince önem vermediklerine inandıkları, çevre dostu ürün, çevreye duyarlı işletme vb. konularında ise sınırlı oranda bilgiye sahip oldukları anlaşılmıştır.
A Review on the Antidiabetic Potential of Medicinal Plants
Authors: Bushnak Razan , El Hajj Mohamad , Jaber Ali
Published: November 2021

Diabetes mellitus has long been seen as a substantial economic burden on patients, their families, and society. Impairment in blood sugar regulation has major health repercussions. Furthermore, untreated diabetes causes major chronic complications like blindness, renal failure, and heart failure, as well as an increase in associated mortality. New anti-diabetic medicines are being researched to help alleviate this issue. Conventional Anti-diabetic medications are beneficial, several synthetic drugs are available in the market to treat diabetes, but they are costly and come with inevitable adverse effects. Medicinal plants, on the other hand, may serve as an alternate source of anti-diabetic agents. According to the World Health Organization, 80 % of the population in underdeveloped nations still relies on traditional medicines or folk medicines, which are largely made from plants, for disease prevention or treatment. For instance, anti- proliferative, anti-viral, anti-inflammatory and anti-hyperglycemic effects. In order to find a natural anti-diabetic source that comes with less side effects, several studies have been conducted. The aim of this work is to review these studies and highlight the potential of plants when it comes to their anti-diabetic effect.
Study of Behavior and the Meaning of Change for Local Communities in the Batu Hijau Mine Area, West Sumbawa
Authors: Karyadi Lalu Wiresapta , Ridwan Ridwan , Juniarsih Nuning
Published: November 2021

This study aims to uncover and explain the meaning of change (development) for local communities, behavioral changes that occur in local communities, and what are the ideal expectations of local communities after the Batu Hijau mining company took place. This study uses qualitative methods and data collection by: in-depth interviews, involved observation and review of relevant documents. Data analysis used an interactive model and the validity of the data was controlled by triangulation. The results of the study show: (1) the local community interprets change as an improvement in living standards while maintaining the values and norms that have been adopted. (2) The presence of the Batu Hijau mining company has led to a transformation of the social behavior of the local community in general but not to the point of eliminating the basic principles of behavior originating from religious values and local traditions. The indications are: 1) the traditional knowledge system (indegenous knowledge) is not used as much in the decision to behave as before 2) the local value system and norms are reduced in their binding power and embracing power to the younger generation, 3) the social behavior and orientation of the cultural values of the local community has reflected the community. open and economically oriented. (3) The ideal hope of the local community is the realization of an environmental conservation system, the availability of job opportunities and business opportunities that become a vehicle for community interaction and the realization of the former mining area as an educational tourism area based on sustainable forest ecology.
Study of Marine Tourism Potential in Takalar
Authors: Latif Abdul
Published: November 2021

This study aims to explain the potential for marine tourism in Takalar Regency and the strategies applied in developing the potential for marine tourism in Takalar Regency. This research was conducted using a descriptive research method with a qualitative approach. The data collection techniques were carried out by means of observation, interviews and documentation. Based on the results of the study, it was found that Takalar district has marine tourism potential spread over several coastal areas of Takalar Regency, for now the most visited marine tourism destinations by tourists are Topejawa beach tourism, Galesong beach tourism, Punaga Beach and PPLH Puntondo. The strategy carried out by the Tourism Office of Takalar Regency is increasing tourism human resources through training and mentoring, strengthening promotions, building facilities and infrastructure at tourist sites and collaborating with tourism stakeholders.
Regulation Model of Corn Trade System Based on Farmer Protection
Authors: Fauzin Fauzin
Published: November 2021

Farmers in the trade chain for agricultural commodities, including corn, are in the weakest position compared to other parties. As a result, the trading system often does not take sides or even tends to harm farmers from year to year. Therefore, state intervention is needed in the context of evaluation which will lead to the reformulation of regulations regarding the maize trade system. Farmers are certainly an important element in realizing food security in this country. Therefore, this research was conducted to produce a regulatory model regarding the corn trade system which has unequivocal support for the protection of farmers. The purpose of this research is to identify the advantages and disadvantages of the current regulatory model, both by the central government and by local governments. To the corn trade system and find a model of corn trading system regulation based on protection for farmers. The research method used in this research is qualitative research and doctrinal legal research with several approaches, namely: statutory approach, analytical approach, and case approach with data collected through literature study and combined with empirical research (field research). This research is very important and useful for stakeholders (especially for farmers, entrepreneurs, and the government) as well as legislators in formulating policies on the trading system of agricultural commodities, especially corn which can ensure that farmers get serious attention and protection from the state.
PENSADORES DA LIBERDADE
Authors: Magera Conceição Márcio , T. P. Conceição Joelma , Costa Ricardo
Published: November 2021

Resenha do livro Pensadores da Liberdade de Rodrigo Constantino