bluuebunny/crossref_metadata_2025 huggingface dataset:
Cultures of accountability: On the intersection of accountability, media and popular reality
Authors: Maras Steven
Published: June 2023

This article proposes the concept of ‘cultures of accountability’ as a way to think about the intersection between media, accountability and popular reality. Noting concerns regarding the emergence of accountability as a cultural keyword, I identify schisms in the deliberation of accountability between an ‘administrative’ and ‘redactive’ formation and explore their interaction and coexistence. Building a bridge between the public administration, journalism studies, media studies and cultural studies literatures, the article posits a more complicated picture of the operation of the ‘media’ in accountability debates and invites analysis and discussion of the communicative and discursive conditions of accountability. Journalistic discourse and practice forms not only a site of encounter between different cultures of accountability but also a forum for discussion of cultural expectations surrounding accountability. Critically revisiting the ‘watchdog’ conception of the news media, the article argues for approaches to journalism open to the yoking of public administration, media accountability and cultural studies approaches and greater awareness of different cultures of accountability.
Cuba in travel journalism in Spain: Discourses about an exceptional destination (2010–19)
Authors: Martínez-González Yanelis
Published: June 2023

This article examines how Cuba was represented as a travel destination in four mainstream media in Spain between 2010 and 2019. The study combined a thematic analysis with a critical discourse analysis (CDA) to focus on their supplements and travel sections. The results revealed that Cuban representations were far from the common discourse attached to ‘sun and beach’ tourism for Caribbean travel destinations. Instead of this, aspects related to society, citizenship and daily life of Cuban people were the most common. Cultural and natural heritage were also salient topics. The CDA revealed about a discourse with some persistence of stereotypes and dominant metaphorical areas that framed Cuba as a ‘paradisiacal’ destination and emphasize the ‘hot’ nature of the island. The study illustrates that the actors in these narratives – tourists and Cuban people – had a variety of roles and agencies. The research contributes to the existing research on Cuban representations and media discourse with evidence about the weight of social issues, culture, heritage, but also remaining postcolonial views to the island, grounded on discourses of otherness and exoticism.
Introduction: Uncomics
Authors: Herd Damon
Published: June 2023

The artists featured in this issue all appeared in C’est Bon Anthology (CBA) #56&57: Uncomics, published by C’est Bon Kultur (CBK), in 2022. CBK’s stated purpose is to support, evolve and disseminate comics with higher artistic ambitions – that is, comics made away from the commercial factory paradigm of the mainstream industry. ‘Un/comics’ was edited by comics artist and researcher Allan Haverholm, who coined the term Uncomics in his master’s thesis to describe comics that are about abstract and nonlinear modes on the periphery of comics.
Editorial
Authors: Round Julia
Published: June 2023

This introduction summarizes the contents of the issue, listing the articles and their main themes, the reviews we have included, and the details of the comics. It points towards the range and breadth of the articles, interviews, reviews and comics gathered here, which take in the intersections of comics and music, poetry, trauma, tradition and humour. It concludes that, taken together, this issue’s content pushes at the boundaries of what might be considered comics: by considering the medium’s relationships with other media, deconstructing its history, iconography and traditions, and exploring the processes, places and influences that underpin its creation.
Compêndio de Direito Empresarial
Authors: Pereira Alexandre Dias
Published: June 2023

Este livro reúne textos de apoio pedagógico sobre noções fundamentais de direito empresarial. Tendo por base as fontes  e a sistematização tradicional do direito comercial, assim  como jurisprudência, este compêndio percorre tópicos como  a qualificação dos atos de comércio e dos comerciantes,  a empresa como sujeito e objeto de negócios (maxime, trespasse e cessão de exploração), os sinais distintivos, as sociedades comerciais (enquanto espécie dominante no universo empresarial, sobretudo as sociedades por quotas e as sociedades anónimas), bem como as empresas públicas, a agência e outros contratos de distribuição comercial, o regime jurídico da concorrência  e a responsabilidade social das empresas.
«¿Quién decide lo que es real y lo que no?». El teatro de Sanchis Sinisterra desde La Corsetería (Nuevo Teatro Fronterizo)
Authors: Pérez-Rasilla Bayo Eduardo
Published: June 2023

El artículo pretende explorar la indagación dramatúrgica de José Sanchis Sinisterra en su etapa más reciente, que se centra en su actividad al frente del Nuevo Teatro Fronterizo, con sede en La Corsetería, desde 2010 a 2022. Su labor pedagógica y experimental durante ese período se caracteriza, en consonancia con lo que ha sido su trayectoria intelectual, por el compromiso político y social de la escritura dramática, por la reivindicación de la memoria, por el impulso de las prácticas de colaboración y de un trabajo que pudiera considerarse artesanal y por el ejercicio de lo que el autor denomina «dramaturgia inducida», por la implicación del receptor y por la búsqueda de una estética que subvierta los principios del realismo y de la verosimilitud. Resulta relevante advertir esos mismos rasgos en la obra teórica y creativa que el dramaturgo ha compuesto durante estos últimos años, singularmente en los dramas Monsieur Goya (Una indagación) y Correr tras un ciervo herido. El análisis de estos dos textos dramáticos pone de relieve su voluntad de experimentar en la escritura con el propósito de trasladar al espectador la responsabilidad de su interpretación última y de conformar lo que entiende como una estética de la borrosidad. Para ello, trabaja con estructuras dramatúrgicas muy elaboradas y complejas, practica formas de alejamiento y de sustracción de la información y apura las posibilidades de lo onírico. Y en ambos textos se abunda en la reflexión sobre cuestiones que constituyen el eje de su teatro, tales como la memoria y la desmemoria, la identidad individual y colectiva o el compromiso cívico y político.
El cine y los escritores: una encuesta de los años 30
Authors: Diez Puertas Emeterio
Published: June 2023

A comienzos de los años treinta, la llegada del sonoro supone un nuevo nacimiento del cine. Casi todo se cuestiona, se suspende, se deja al vaticinio. ¿El cine sonoro será teatro filmado? ¿Tiene sentido rodar una misma película en varios idiomas? ¿Debe ser el acento de determinada región de España la pronunciación de todo el cine hispano? Hay una necesidad de encontrar respuestas. El artículo estudia una de las iniciativas que en este sentido acomete Manuel Villegas López, uno de los críticos cinematográficos más importantes de España, entonces un joven en sus primeros pasos. Villegas decide entrevistar para Unión Radio a algunos de los escritores más importantes del momento esperando que sus respuestas señalen el camino.
An Automated Tissue Systems Pathology Test Can Standardize the Management and Improve Health Outcomes for Patients With Barrett's Esophagus
Authors: Duits Lucas C. , Khoshiwal Amir M. , Frei Nicola F. , Pouw Roos E. ,   Barrett's SURF LGD Study Pathologists Consortium, Smolko Christian , Arora Meenakshi , Siegel Jennifer J. , Critchley-Thorne Rebecca J. , Bergman Jacques J.G.H.M.
Published: June 2023

INTRODUCTION:

Low-grade dysplasia (LGD) in Barrett's esophagus (BE) is associated with an increased risk of progression to high-grade dysplasia or esophageal adenocarcinoma. However, because of substantial interobserver variability in the diagnosis of LGD, a patient's management plan and health outcome depend largely on which pathologist reviews their case. This study evaluated the ability of a tissue systems pathology test that objectively risk stratifies patients with BE (TissueCypher, TSP-9) to standardize management in a manner consistent with improved health outcomes for patients with BE.

METHODS:

A total of 154 patients with BE with community-based LGD from the prospectively followed screening cohort of the SURF trial were studied. Management decisions were simulated 500 times with varying generalist (n = 16) and expert (n = 14) pathology reviewers to determine the most likely care plan with or without use of the TSP-9 test for guidance. The percentage of patients receiving appropriate management based on the known progression/nonprogression outcomes was calculated.

RESULTS:

The percentage of patients with 100% of simulations resulting in appropriate management significantly increased from 9.1% for pathology alone, to 58.4% when TSP-9 results were used with pathology, and further increased to 77.3% of patients receiving appropriate management when only TSP-9 results were used. Use of the test results also significantly increased the consistency of management decisions for patients when their slides were reviewed by different pathologists (P < 0.0001).

DISCUSSION:

Management guided by the TSP-9 test can standardize care plans by increasing the early detection of progressors who can receive therapeutic interventions, while also increasing the percentage of nonprogressors who can avoid unnecessary therapy and be managed by surveillance alone.
Bayesian optimization of multi-layer perceptron models for power distribution system state estimation
Authors: Carmichael James , Liao Yuan
Published: June 2023

Feedforward multilayer perceptron models (MLPs) have been applied to power distribution system state estimation (DSSE) in the past. Existing methods usually employ an ad-hoc or trial and error approach to MLP hyperparameter selection, and thus a systematic way of selecting the optimal hyperparameters including the number of neurons per hidden layer, learning rate, number of training epochs and training batch size is desirable and needed. This paper presents an approach based on Bayesian Optimization with Gaussian Processes for selecting MLP model hyperparameters for state estimation purposes. Results of the optimized MLP models are presented alongside the unoptimized models to compare performance of training, testing, and validation in terms of root-mean-squared-error (RMSE). Additionally, machine learning pipelines were employed and total execution time (seconds) for each trial is presented. The study shows that the MLP models obtained through the proposed optimization method outperform unoptimized models in terms of generalization capability for unseen, new cases.
“She Deserves It All (?)”: Romance and Tradition in Qiong Yao Films of the 1960s
Authors: Zhou Xuelin
Published: June 2023

Qiong Yao films are known for telling stories of romance. This essay focuses on the female characters in Qiong Yao films produced by the Grand Motion Picture Company (GMP) in the 1960s. Founded by Li Han-xiang in 1963, GMP played a key role in the evolution of Taiwan cinema in general and Qiong Yao films in particular. The 1960s was to Taiwan a time of political and ideological conservatism. Discipline and obedience to authorities were prioritized as an official strategy to celebrate the traditional values and principles of Chinese culture. The Confucian-oriented ideology toward women dominated. The paper proposes that most women portrayed in the Qiong Yao films by GMP remain in the traditional status, emotionally and economically dependent on men. The paper posits that the gender-based/biased authoritarian hierarchy represented in these romantic dramas was closely associated to the patriarchal social structure and the mainstream political ideology. GMP’s 1968 film Love Eternal will be used as a case study to show how “the limits of proprieties” must be followed and what devastating effects were produced in the case when these traditional values were challenged and violated.
Organizing Expertise During a Crisis. France and Sweden in the Fight Against Covid-19
Authors: Borraz Olivier , Jacobsson Bengt
Published: June 2023

In the fight against the Covid-19 virus, France and Sweden stood at opposing ends along a continuum: one country went for lockdowns; the other relied on voluntary measures. Both strategies were shaped by the governing structures in each country: in France complex and fragmented organizational arrangements focusing on health security, in Sweden a single dominant agency maintaining a broad public health perspective. Using concepts from organization theory – loose versus tight coupling and exploitation versus exploration – we show how the divergent strategies evolved in both countries. While loosely coupled organizational arrangements were rapidly tightened in Sweden, the system in France went in the opposite direction becoming loosely coupled. While the Swedish case was mainly one of exploitation of existing knowledge and expertise, more unchartered territories were explored in France. While alignment across actors in Sweden took place with one dominant agency in the center, alignment in France was related to actions of neighboring countries. Evidently, there was more than one way to fight the pandemic.
Overexpression of LINC00607 inhibits cell growth and aggressiveness by regulating the miR-1289/EFNA5 axis in non-small-cell lung cancer
Authors: Zhang Li , Liu Huimin , Long Yan , Zhang Yuan
Published: June 2023

Long non-coding RNAs (lncRNAs) play a key role in cancer progression, including non-small-cell lung cancer (NSCLC). LncRNA long intergenic non-protein-coding RNA 00607 (LINC00607) was previously discovered to be downregulated in lung adenocarcinoma tissues. Nevertheless, the potential role of LINC00607 in NSCLC is still unclear. The expression of LINC00607, miR-1289, and ephrin A5 (EFNA5) in NSCLC tissues and cells was tested by reverse transcription quantitative polymerase chain reaction. Cell viability, proliferation, migration, and invasion were measured by 3-(4,5-dimethylthiazole-2-y1)-2,5-diphenyl tetrazolium bromide, colony formation, wound healing, and Transwell assays. The relationship among LINC00607, miR-1289, and EFNA5 in NSCLC cells was verified by the luciferase reporter assay, RNA pull-down assay, and RNA immunoprecipitation assay. In this study, LINC00607 was downregulated in NSCLC, and its low level is associated with poor prognosis of NSCLC patients. Furthermore, LINC00607 overexpression repressed NSCLC cell viability, proliferation, migration, and invasion. LINC00607 bound with miR-1289 in NSCLC. EFNA5 was a downstream target of miR-1289. EFNA5 overexpression also inhibited NSCLC cell viability, proliferation, migration, and invasion. EFNA5 knockdown antagonized the influence of LINC00607 overexpression on NSCLC cell phenotypes. Overall, LINC00607 serves as a tumor suppressor gene in NSCLC through binding with miR-1289 and modulating the level of EFNA5.
Diagnostic genomic sequencing in critically ill children
Authors: Auber Bernd , Schmidt Gunnar , Du Chen , von Hardenberg Sandra
Published: June 2023

Rare genetic diseases are a major cause of severe illnesses and deaths in new-borns and infants. Disease manifestation in critically ill children may be atypical or incomplete, making a monogenetic disease difficult to diagnose clinically. Rapid exome or genome (“genomic”) sequencing in critically ill children demonstrated profound diagnostic and clinical value, and there is growing evidence that the faster a molecular diagnosis is established in such children, the more likely clinical management is influenced positively. An early molecular diagnosis enables treatment of critically ill children with precision medicine, has the potential to improve patient outcome and leads to healthcare cost savings. In this review, we outline the status quo of rapid genomic sequencing and possible future implications.
Reconfigurable nonlinear optical element using tunable couplers and inverse-designed structure
Authors: Nikkhah Vahid , Mencagli Mario Junior , Engheta Nader
Published: June 2023

In recent years, wave-based analog computing has been at the center of attention for providing ultra-fast and power-efficient signal processing enabled by wave propagation through artificially engineered structures. Building on these structures, various proposals have been put forward for performing computations with waves. Most of these proposals have been aimed at linear operations, such as vector-matrix multiplications. The weak and hardly controllable nonlinear response of electromagnetic materials imposes challenges in the design of wave-based structures for performing nonlinear operations. In the present work, first, by using the method of inverse design we propose a three-port device, which consists of a combination of linear and Kerr nonlinear materials, exhibiting the desired power-dependent transmission properties. Then, combining a proper arrangement of such devices with a collection of Mach–Zehnder interferometers (MZIs), we propose a reconfigurable nonlinear optical architecture capable of implementing a variety of nonlinear functions of the input signal. The proposed device may pave the way for wave-based reconfigurable nonlinear signal processing that can be combined with linear networks for full-fledged wave-based analog computing.
Sahara Reporters and Premium Times online coverage of the Russia–Ukraine war
Authors: Omoera Osakue Stevenson , Nwaoboli Emeke Precious
Published: June 2023

Purpose

The mass media have continued to be significant news sources for human society, particularly during conflict and war. The media dependency theory posits that during crisis or instability, society relies more on traditional and new media to help it understand the developments in the war. This article investigated the frequency of the coverage of the Russia–Ukraine War by Sahara Reporters and Premium Times, ascertained the most dominant tone used by Sahara Reporters and Premium Times in the reporting of the Russian–Ukraine War, and unfurled the frame of coverage of Russian–Ukraine War by Sahara Reporters and Premium Times.

Theoretical and Methodical Considerations

Anchored in Robert Entman’s Framing Theory, online publications of Sahara Reporters and Premium Times from March 2022 to September 2022 served as the population of the study and the census sampling technique was used to draw a sample for the study. The explanation-building model was the method of data analysis.

Findings

Results showed that Sahara Reporters and Premium Times reports on the 2022 Russian–Ukraine War were frequent. Also, they paid more attention to the impacts of the war on Nigerian emigrants or students overseas in Russia and Ukraine.

Implications

Our findings suggest that online newspapers mostly toned the Russian–Ukraine War in negative slants and framed the stories highlighting the impact of the war on Nigerians, especially Nigerian students in Russia and Ukraine.

Value

The article brings a new perspective to the Russian–Ukraine War in media scholarship by examining Nigeria’s online news reporting of the Russian–Ukraine conflict. It is, therefore, recommended that Nigerian online newspapers not solely focus on negative reports of the war and its implications for stakeholders in Nigeria. They should adopt a more diverse range of frames and tones in their coverage, to influence stakeholders to take action to prevent wars and hold the Nigerian government accountable for providing adequate infrastructure and human capital that discourages emigration in search of a better life both academically and otherwise.
Glycoprofiling of early non-small cell lung cancer using lectin microarray technology
Authors: Zeng Lingyan , Xian Jinghong , Chen Hongyu , Mao Shengqiang , Liu Lei , Zhang Li
Published: June 2023

Objectives

Non-small cell lung cancer (NSCLC) is one of the most common malignancies in the world with a high incidence and it lacks effective biomarkers for early-stage detection. In this investigation, we aimed to investigate the alterations in plasma glycans related to NSCLC and assess the possibility of plasma glycopatterns as potential biomarkers for the diagnosis of NSCLC.

Methods

First, plasma samples from 16 patients with early-stage lung adenocarcinoma (LUAD), 16 patients with early-stage Lung squamous cell carcinoma (LUSC), and 16 healthy volunteers, were selected for inclusion in this study to probe the difference in plasma glycopatterns using lectin microarrays. Then, the diagnostic effectiveness of the candidate lectins was evaluated using ROC.

Results

In contrast to the NL group, seven candidate lectins offered potential diagnostic utility in the NSCLC (LUAD and LUSC) group. F17AG was significantly altered in LUSC with an AUC of 0.818 (adj.P.Val<0.05) compared to NL samples. There were 20 differentially expressed lectins in the LUAD group compared to the NL group. Based on the AUC values (AUC>0.800) and the normalized fluorescence intensities of the lectins, we selected eight lectins, GAL2, PTL-1, GNA, SSA, LENTIL, CA, PHA-E, and MAA to perform logistic regression analysis, and found that the combination of these eight candidate lectins had high diagnostic potential.

Conclusions

The results of this study should help to distinguish between NSCLC and NL based on changes in plasma glycopatterns, which have a great deal of potential to be biomarkers for diagnosing NSCLC.
Evaluación de las dinámicas de la cooperación sino-brasileña en el siglo XXI
Authors: He Lile , Zhou Nan
Published: June 2023

Al inicio del siglo XXI, las relaciones sino-brasileñas se han vuelto cada vez más estrechas. Este estudio consiste en una comparación entre el desarrollo de la cooperación sino-brasileña durante el mandato de Lula y el de Bolsonaro con el fin de evaluar las influencias de las diferentes orientaciones de políticas del gobierno brasileño sobre los intercambios mencionados. Evaluando factores domésticos de Brasil e internacionales como variables, este estudio se enfoca en las dinámicas que impulsan la cooperación entre China y Brasil en los dos periodos mencionados y revela que las relaciones económicas entre los dos países emergentes muestra cierta resiliencia a pesar de la existencia de una serie de desafíos.
A comparison of learning-based approaches for the corrosion detection on barrels in industrial applications
Authors: Haitz Dennis , Hübner Patrick , Ulrich Markus , Jutzi Boris
Published: June 2023

Machine-learning-based (ML) segmentation in the image domain can be utilized for the detection of corrosion on the surface of industrial objects. This research provides a comparison of techniques using convolutional neural networks (CNNs) on the one hand, and random forest (RF) classifiers within RGB and HSV feature spaces on the other hand. CNN-based approaches usually need a large amount of data for training in order for the network to converge and generalize well on new data. Due to the low amount of data provided, we apply a set of methods to increase the generalization ability of the model. These methods can be categorized into data augmentation, selection of larger and smaller models and pretraining strategies like self supervised learning (SSL). The RF classifiers on the other hand are trained per pixel, so that the amount of data is determined by the image size. The object to be tested is a barrel made of metal, from which the image of the coat is used as the training data, and the image of the bottom as test data. We found that a RF classifier in the RGB feature space outperforms the CNNs by seven percentage points regarding the f
1-score of the corrosion class.
Kinetic study of Ru(III) – catalyzed oxidation of L-phenylalanine by hexacyanoferrate(III) in an anionic surfactant medium
Authors: Srivastava Abhishek , Singh Ruchi , Srivastava Neetu , Naik Radhey Mohan
Published: June 2023

The kinetic investigation of Ru(III) promoted oxidation of L-phenylalanine (L-PheAla) by [Fe(CN)6]3−has been performed in anionic sodium dodecyl sulfate (SDS) micellar medium by recording the decrease in absorbance at 420 nm corresponding to [Fe(CN)6]3−using an UV–visible spectrophotometer. Using the pseudo-first-order condition, the course of the reaction was studied as a function of [Fe(CN)63−], ionic strength, [OH−], [SDS], [Ru3+], [L-PheAla] and temperature by changing one variable at a time. The results exhibit that [OH−], [SDS], and [L-PheAla] are the crucial parameters that have an appreciable influence on the reaction rate. The reaction exhibits first-order kinetics in concentration ranges of Ru(III), [Fe(CN)6]3−and at low [L-PheAla] and [OH−] concentrations. The incremental trend observed in the reaction rate with electrolyte concentration shows a positive salt effect. The reaction rate is almost 10 times faster in SDS micellar medium than in aqueous medium. [Fe(CN)6]3−has no appreciable effect on the CMC of SDS, since the polar head of SDS and [Fe(CN)6]3−are both negatively charged. The K+obtained from K3[Fe(CN)6] and KNO3decreases the repulsion between the negatively charged heads of the surfactant molecules, which decreases the CMC of SDS. The activation parameters also support the outer-sphere electron transfer mechanism.
La importancia de la inteligencia artificial en las comunicaciones en los procesos marketing
Authors: Zúñiga Freddy , Mora Poveda Diego Alejandro , Molina Mora Diego Patricio
Published: June 2023

En estos días ya no es inusual hablar de marketing, y que es lo que conlleva el empleo del mismo dentro de las organizaciones, sabemos que se ocupa de cada interacción posible entre las empresas y las personas, y por qué no decirlo, el marketing permite alcanzar los objetivos organizacionales por medio de la creación de experiencias cada vez más adaptables e inteligentes para los clientes, para ello es necesario el despliegue de tres tipos de capacidades: creativas, analíticas y tecnológicas, en el uso de estas capacidades es donde interviene el empleo de la inteligencia artificial; la correcta aplicación de esta, permite la optimización de recursos y disminución de costes; pero sobre todo tiene un impacto transcendental para los clientes, ya que facilita el anticiparnos a las necesidades de ellos y ofrecer soluciones a las mismas, inclusive antes de que ellos las busquen mediante el  análisis predictivo; o, empleando cookies, técnicas Deep learning y el uso de chatbots, se pueda obtener datos de variadas fuentes de información para crear contenido de publicidad lo más personalizada posible. Este artículo pretende realizar una exhaustiva revisión bibliográfica sobre esta temática, teniendo como base información que han sido publicadas en bases de datos científicas, que permitan obtener un marco de referencia sobre la importancia del empleo de la inteligencia artificial en el marketing, que afirme que el uso de IA en el marketing actual es vital para la evolución, adaptabilidad y supervivencia de las organizaciones en este nuevo mundo de transformación digital 4.0.
A sterol‐PI(4)P exchanger modulates the Tel1/ATM axis of the DNA damage response
Authors: Ovejero Sara , Kumanski Sylvain , Soulet Caroline , Azarli Julie , Pardo Benjamin , Santt Olivier , Constantinou Angelos , Pasero Philippe , Moriel‐Carretero María
Published: June 2023

Upon DNA damage, cells activate the DNA damage response (DDR) to coordinate proliferation and DNA repair. Dietary, metabolic, and environmental inputs are emerging as modulators of how DNA surveillance and repair take place. Lipids hold potential to convey these cues, although little is known about how. We observed that lipid droplet (LD) number specifically increased in response to DNA breaks. Using Saccharomyces cerevisiae and cultured human cells, we show that the selective storage of sterols into these LD concomitantly stabilizes phosphatidylinositol‐4‐phosphate (PI(4)P) at the Golgi, where it binds the DDR kinase ATM. In turn, this titration attenuates the initial nuclear ATM‐driven response to DNA breaks, thus allowing processive repair. Furthermore, manipulating this loop impacts the kinetics of DNA damage signaling and repair in a predictable manner. Thus, our findings have major implications for tackling genetic instability pathologies through dietary and pharmacological interventions.
GAPDH facilitates homologous recombination repair by stabilizing RAD51 in an HDAC1‐dependent manner
Authors: Shi Munan , Hou Jiajia , Liang Weichu , Li Qianwen , Shao Shan , Ci Shusheng , Shu Chuanjun , Zhao Xingqi , Zhao Shanmeizi , Huang Miaoling , Wu Congye , Hu Zhigang , He Lingfeng , Guo Zhigang , Pan Feiyan
Published: June 2023

Homologous recombination (HR), a form of error‐free DNA double‐strand break (DSB) repair, is important for the maintenance of genomic integrity. Here, we identify a moonlighting protein, glyceraldehyde‐3‐phosphate dehydrogenase (GAPDH), as a regulator of HR repair, which is mediated through HDAC1‐dependent regulation of RAD51 stability. Mechanistically, in response to DSBs, Src signaling is activated and mediates GAPDH nuclear translocation. Then, GAPDH directly binds with HDAC1, releasing it from its suppressor. Subsequently, activated HDAC1 deacetylates RAD51 and prevents it from undergoing proteasomal degradation. GAPDH knockdown decreases RAD51 protein levels and inhibits HR, which is re‐established by overexpression of HDAC1 but not SIRT1. Notably, K40 is an important acetylation site of RAD51, which facilitates stability maintenance. Collectively, our findings provide new insights into the importance of GAPDH in HR repair, in addition to its glycolytic activity, and they show that GAPDH stabilizes RAD51 by interacting with HDAC1 and promoting HDAC1 deacetylation of RAD51.
Mobilne aplikacije i phygital koncept u sektoru maloprodaje u funkciji obogaćivanja kupovnog iskustva i razvoja CRM-a
Authors: Krajnović Aleksandra , Živković Marina , Ražov Antonija
Published: June 2023

U ovom radu problematizira se pitanje promocije u distributivnim lancima i aktualno stanje kada je riječ o korištenju promotivnih alata u distribucijskom kanalu, kao i o njihovoj kombinaciji, u kontekstu višekanalne marketinške strategije, ali i obogaćivanja korisničkog iskustva i CRM-a. Autorice polaze od teze da su novi promotivni alati, posebice njihovo korištenje u digitalnom prostoru, slabije zastupljeni u trgovačkim lancima u odnosu na njihovu upotrebu u marketingu industrijskih proizvođača. U radu se daje prikaz konceptualnog okvira vezanog uz navedenu problematiku te se naglašava značenje optimalne kombinacije online i offline promotivnih kanala, što je od iznimne važnosti u aktualnoj eri tzv. phygital marketinga. U radu se u fokus razmatranja postavljaju mobilne aplikacije kao suvremeni digitalni kanal promocije, te njihov dizajn, sadržaj i model korištenja na primjerima dvaju trgovačkih centara – Lidl i Kaufland, s komparativnom analizom. Nadalje se prikazuju rezultati primarnog istraživanja provedenog na segmentu potrošačke generacije mladih, kojime se pokušalo saznati njihove stavove i mišljenja o navedenim aplikacijama. U posljednjem dijelu rada daje se kritički osvrt autorica na rezultate, zaključni stavovi i smjernice za daljnja istraživanja. Znanstveni doprinos rada sastoji se u konceptualizaciji upotrebe mobilnih aplikacija prema modelu Yadav & Pavlou (2020) koji digitalizaciju poslovanja stavljaju u središte marketinških i poslovnih aktivnosti te koji u svojem modelu promotivne alate promatraju kao ishodište razvoja dugoročnih odnosa prvenstveno na relacijama: poduzeće – klijent i klijent – poduzeće. Praktične implikacije rada ogledaju se u doprinosu spoznajama relevantnima za donošenje strateških marketinških odluka u trgovačkim poduzećima i u kanalu opskrbe općenito. Ograničenje istraživanja je u fokusu na segment mladih u primarnom istraživanju pa se za daljnja istraživanja preporučuje proširenje analiza i na druge segmente potrošača, ali i daljnji razvoj konceptualizacije znanstvene teorije marketinga u području promocije i digitalizacije u sektoru trgovine robe široke potrošnje.
ANALISIS PEMBUATAN COWL DRAPERY DENGAN TEKNIK DRAPING PADA BUSANA
Authors: Nurlita Ela , Yasnidawati Yasnidawati
Published: June 2023

Abstract. This study aims to describe the results of cowl drapery using the draping technique. The type of research used is applied research. The object of research is cowl drapery using draping technique. The research instrument uses an assessment format with a Likert Scale. The assessment is carried out by 3 panelists, namely lecturers who are experts in the field of clothing, by fitting. The data analysis technique used is quantitative descriptive and inferential analysis. The results of the cowl drapery using the draping technique show that the results of the cowl drapery using the draping technique obtained an assessment result with a percentage value of 80.21% categorized as appropriate. Based on the t-test, it was found that the average results were significant between the results of cowl drapery using the draping technique with a significance level of 0.05.

Keywords:  Cowl drapery; draping;

 

Abstrak. Penelitian ini bertujuan untuk  untuk mendeskripsikan hasil cowl drapery menggunakan Teknik Draping. Jenis penelitian yang digunakan adalah penelitian terapan. Objek penelitian yaitu cowl drapery menggunakan teknik draping. Instrumen penelitian memakai format penilaian dengan Skala Likert. Penilaian dilakukan oleh 3 orang panelis yaitu dosen yang ahli dalam bidang busana, dengan cara fitting. Teknik analisis data yang digunakan adalah deskriptif kuatitatif dan analisis inferensial. Hasil cowl drapery menggunakan Teknik Draping menunjukkan hasil cowl drapery menggunakan teknik draping didapatkan hasil penilaian dengan nilai persentase sebesar 80.21 % dikategorikan Sesuai. Berdasarkan uji t didapatkan hasil rata-rata penilaian yang signifikan antara hasil jadi cowl drapery menggunakan teknik draping dengan taraf signifikansi sebesar 0.05.

Kata Kunci: Cowl drapery; draping;
TUNIK MENGGUNAKAN PENGAPLIKASIAN TEKNIK COLET-BOSHI SHIBORI PADA WANITA KARIR DENGAN BENTUK TUBUH PENDEK GEMUK
Authors: ERMALENA SITI SARAH , WENING SRI , BUDIASTUTI EMY
Published: June 2023

Abstrak. Tujuan penelitian ini adalah untuk mengetahui cara pembuatan motif menggunakan teknik colet-boshi shibori, mengembangkan desain tunik mengetahui hasil uji produk tunik untuk wanita karir dengan bentuk tubuh tidak ideal. Penelitian ini merupakan jenis penelitian pengembangan (R&D) menggunakan model PPE (Planning, Production and Evaluation). Metode pengumpulan datanya sendiri menggunakan studi literature, angket (kuisioner) dan dokumentasi. Sedangkan teknik analisis data yang digunakan menggunakan 3 teknik yaitu : (1) pengukuran persepsi visual, (2) uji validasi isi, dan (3) analisis data deskriptif kuantitatif untuk uji kelayakan produk. Hasil uji produk tunik yang diperoleh dari hasil rerata penilaian ahli (judgement expert) yang terdiri dari 3 orang ahli yaitu : 94,3, 88,6 dan 91,4. Rerata dari ketiga penilaian adalah 91,4. Berdasarkan hasil rerata tersebut maka pengembangan teknik colet dan bosgi shibori pada wanita karir dengan bentuk tubuh tidak ideal memiliki kualifikasi sangat baik dengan pencapaian 91,4%.

Kata Kunci: tunik, teknik colet, teknik boshi, shibori, wanita, karir, bentuk tubuh pendek gemuk
Xylo-oligosaccharides production by autohydrolysis of corn fiber separated from DDGS
Authors: Samala Aditya , Srinivasan Radhakrishnan , Yadav Madhav P. , Kim Tae-Jo , Prewitt Lynn
Published: June 2023

Xylo-oligosaccharides (XOS) are reported to have beneficial health properties, and they are considered to be functional food ingredients. Corn fiber separated from distillers dried grains with solubles (DDGS) could be a valuable feedstock for XOS production. The objective of this study was to determine the efficacy for autohydrolysis to produce XOS using fiber separated from DDGS and to determine the optimum temperature for XOS production. Corn fiber was treated with deionized water in a Parr-reactor, at temperatures ranging from 140 to 220 °C to produce XOS. The maximum total yield of XOS in the solution was 18.6 wt% of the corn fiber at 180 °C.
Language as an indicator of the Ukrainian national identity and civilization choice of the Kyivans
Authors:   Institute of City Development, Zalizniak Hanna
Published: June 2023

The article has been the objective of the study of the language factor in formation of the Ukrainian national identity. Ukrainian researchers tended to reduce national identity to a civic model without taking ethnic and linguistic color into account. In circumstances of the full-scale military aggression of the Russian Federation against Ukraine importance of the components of ethnic national self-identification in formation of the Ukrainian na­tional identity has come to be topical. Based on the results of the survey of the Kyivans in 2020 separated out were social groups with different depth of manifestations of civic, po­litical and cultural national identities. A comparison of the share of the Kyivans with the same level of civic identity but differ in language preferences (the language of everyday communication and the language that Kyivans define as their native one) showed diffe­rences in determining the civilizational future of Ukraine. The highest commonality in views on the country civilizational choice is drmonstrated by the people of Kyiv who on condition of common civic identity are Ukrainian-speaking or bilingual but, above all, recognize Ukrainian to be their native language. In addition, for the cultural component of the Ukrainian identity, the indicator of defining one’s own native language appeared to be more demonstrative and important than that of everyday communication. Bilingualism can be considered as a transitional stage in the restoration of Ukrainian national identity. At the current stage of Ukrainian statehood development efforts to limit Ukrainian na­tional identity only to the political component without taking into account cultural ele­ments seem to be short-sighted and contradictory among which language preferences have come to be the leading marker. And the indicator of defining one’s own native language is currently a system indicator in the totality of indicators of the Ukrainian national identity. Keywords: national identity, national self-identification, civilizational choice, language prefe­rences, native language, the language of everyday communication.
Representation of the subconcept Mother of God in modern Middle-upper-dnieper and Hutsul dialects
Authors:   Institute of the Ukrainian Language of the National Academy of Sciences of Ukraine, Diachuk Vira
Published: June 2023

It has been acknowledged that mental formations like concepts and subconcepts occupy an important place in national worldview system, because they represent the community value attitude to the cultural phenomenon. Verbalization of the lower-level cognitive structures testifies their place in linguistic worldview and represent culturally determined knowledge about them. The purpose of this study is to find out the common semantic features in concep­tualization of Mother of God image and describe the peculiarities of its verbalization in speech of modern Middle-upper-Dnieper and Hutsul speakers. To achieve the objectives we used a comparative method which is suitable for identifying peculiarities of subcon­cept verbalization in the Middle-upper-Dnieper and Hutsul dialects. The results of this study show that the subconcept MOTHER OF GOD is objecti­fied in seven common cognitive features in researched linguistic areas: “Mary is a wom­an born Jesus Christ”; “Mother of God is a holy mother”; “Our Lady is a protector”; “Mother of God helps people”; “Virgin Mary helps girls to get married”; “Mother of God is respected”; “Our Lady is an earthly woman”. Results also reveal that the seman­tic features of analyzed cognitive item are concentrated around maternal, intercessory and glorifier aspects. Moreover, our research specifies two types of subconcepts verbal­ization in the Middle-upper-Dnieper and Hutsul dialects. They are lexical and syntactic. This study emphasizes more important place of the subconcept MOTHER OF GOD in the Hutsul conceptual worldview. It is proved by larger number of language representatives found in the Hutsul dialects and rapprochement of sacred understanding about earth and Mother of God. Keywords: subconcept, Mother of God, linguistic worldview, the Middle-upper-Dnieper dia­lects, the Hutsul dialects.
Patterns of knowledge and use of tropical plants in homegardens of Southern Morelos, Mexico
Authors: Ortiz-Sánchez Amanda , Romero-Manzanares Angélica , Monroy-Ortiz Columba , Luna Cavazos Mario
Published: June 2023

The aim of this research is to identify the patterns of use and knowledge of plant species growing in selected tropical homegardens in southern Morelos, Mexico. The method consisted of obtaining informed consent, interviews with homegarden managers, recording socioeconomic data, visits to the interior of each selected homegarden, and personal observations. Data were analyzed through multivariate analyses. The results included a floristic composition (132 species) and eight types of use. Grouping of homegardens by type of use differentiated two main groups: homegardens where principal use is for food plants, and others mainly for ornamental plants. Were found significant differences between homegardens by the number of species and type of use. The grouping of species by number of uses revealed two groups; the patterns of use of plants in homegardens differed according to the user’s preferences; multiuse species were appreciated in group two, which dominated the ornamentals.  It was found a significant correlation between age and number of plants known for the owners of the homegardens; while occupation, schooling, and income had no correlation. In conclusion, we rejected the hypothesis of nullity due to differences between richness and the preference of species, the management of homegardens, and by the null influence of the socioeconomic factors studied, with the exception of the age owners and their knowledge of the species.
Wild fauna as roadkill on a highway in the semiarid region of northeastern Brazil
Authors: De Lima Ferreira Erly , Lima Silvio , S. Souza J. Weverton , Medeiros Paulo Roberto
Published: June 2023

The death of wild vertebrates run over by motor vehicles on highways is one of the main causes of the loss of wildlife diversity. The aim of the present study was to investigate the diversity of wild fauna in roadkill incidents on a stretch of highway in the semiarid region of Brazil. The survey was conducted between March 2020 and May 2021 through active searches using a motorcycle. Killed vertebrates were analyzed and photographed in situ. Wild fauna was studied based on ecological descriptors, speed of movement and average rate of roadkill incidents. We compared total observed richness to that expected using nonparametric estimators. A total of 464 road-killed vertebrates were represented by two species of amphibians, 17 reptiles, 17 birds and 10 mammals. Amphibians were the most affected, totaling 245 individuals. Colubridae was the family with the largest number of species affected. Boiruna sertaneja and Boa constrictor were the only medium-size to large snakes killed. Herpailurus yagouaroundi and Leopardus tigrinus are respectively categorized as “least concern” and “vulnerable” according to the IUCN. The species accumulation curves continued to rise, showing no sign of approaching to an asymptote. Chao 2 and Jack 2 were the main estimators for road-killed wild vertebrates considering total richness. The diversity reported here is considered to be underestimated and greater monthly sampling efforts are required. Conservation strategies are urgently needed for the protection of wild vertebrate fauna to mitigate the staggering loss of biodiversity caused by the construction and operation of roads and highways in Brazil.
Skutki prawne nieudzielenia przez adresata odpowiedzi na interpelację lub udzielenia odpowiedzi po terminie
Authors:   Uniwersytet SWPS w Warszawie, Chmaj Marek
Published: June 2023

The article presents the essence of parliamentary interpellations, refers to the obligation incumbent on the addressee to provide an answer within the time limit indicated in the Constitution. The author is of the opinion that not replying or replying after the deadline is a constitutional tort and is subject to liability before the State Tribunal. The currently occurring, rather negative parliamentary practice necessitates appropriate amendments to the Parliament’s Rules of Procedure. These changes should also cover the issues of abuse of the right of interpellation and enquiry by.
Wiedza wyborcza pokolenia „Z” w perspektywie badania ilościowego nad warszawskimi licealistami
Authors:   Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Hrehorowicz Arleta , Kowalczyk Tomasz ,   Kujawsko-Pomorska Szkoła Wyższa w Bydgoszczy
Published: June 2023

The research problem of the described study was the electoral knowledge of representatives of generation Z. The aim of the content of the article is to clarify the extent to which today’s secondary school students are familiar with the principles of electoral law and to determine the significance of gender on their level of knowledge in this area; obtaining information on the self-assessment of knowledge regarding electoral law and elections, as well as the importance of the length of learning for the level of self-assessment, as well as learning about the most convenient form of voting in the opinion of secondary school students. Research to date in this area has mainly focused on the millennial generation, not on today’s youth. This text therefore seeks to fill this gap. The study was carried out by means of a diagnostic survey using a survey technique and an online survey questionnaire research tool.
The Constitutional Category of “Beauty” in the Polish Legal Order
Authors:   Rzeszow Uniwersity, Maroń Grzegorz
Published: June 2023

The subject of the article is a reference to beauty in the preamble to the Constitution of the Republic of Poland of 1997. First, the legislative history of the fragment of the introduction to the Constitution, which constitutes beauty as a universal value, has been presented. Then it has been interpreted, taking the position that the constitutional concept of beauty is not only an aesthetic category but also an ethical category. Finally, a study of jurisprudence and normative acts has allowed to define the scope of beauty operationalization as a constitutional value. Critical reference has been made to the state of affairs in which beauty, being an element of constitutional axiology, plays a barely noticeable role in the practice of creating and applying Polish law.
How Do US Congress Members Advertise Climate Change: An Analysis of Ads Run on Meta’s Platforms
Authors: Aisenpreis Laurenz , Gyrst Gustav , Sekara Vedran
Published: June 2023

Ensuring transparency and integrity in political communication on climate change has arguably never been more important than today. Yet we know little about how politicians focus on, talk about, and portray climate change on social media. Here we study it from the perspective of political advertisement. We use Meta’s Ad Library to collect 602,546 ads that have been issued by US Congress members since mid-2018. Out of those only 19,176 (3.2%) are climate-related. Analyzing this data, we find that Democrats focus substantially more on climate change than Republicans, with 99.7% of all climate-related ads stemming from Democratic politicians. In particular, we find this is driven by a small core of Democratic politicians, where 72% of all impressions can be attributed to 10 politicians. Interestingly, we find a significant difference in the average amount of impressions generated per dollar spent between the two parties. Republicans generate on average 188% more impressions with their climate ads for the same money spent as Democrats. We build models to explain the differences and find that demographic factors only partially explain the variance. Our results demonstrate differences of climate-related advertisements of US congress members and reveal differences in advertising characteristics between the two political parties. We anticipate our work to be a starting point for further studies about climate-related ads on Meta’s platforms.