bluuebunny/crossref_metadata_2025 huggingface dataset:
TANTRA BUDISTA NO MEDIEVO INDIANO: A RELAÇÃO ENTRE O MOVIMENTO MAHĀSIDDHA E A SEXUALIDADE SAGRADA
Authors: Parente Ferreira Dias Rafael
Published: November 2024

Este artigo tem como objetivo fazer uma análise sobre a relação entre o tantra budista e o movimento Mahāsiddha, que floresceu durante o medievo indiano. Os Mahāsiddhas eram yogues e mestres espirituais que desempenharam um papel crucial na expansão e evolução dos ensinamentos budistas. Conhecidos por suas práticas excêntricas e pouco convencionais, incorporaram elementos relacionados à sexualidade sagrada, bem como a exploração de estados de consciência alterados, objetivando alcançar os cumes mais elevados da espiritualidade budista. Ademais, em muitas narrativas sobre esses seres aparece a menção aos textos tântricos, indicando que a relação entre eles é inseparável e central na transmissão e expansão do tantrismo budista ao longo da história. Quanto à metodologia, trata-se de um artigo essencialmente bibliográfico, utilizamos como referencial teórico obras de pesquisadores acadêmicos e também autoridades da tradição mahāyāna e vajrayāna.
DO PARADIGMA PREDATÓRIO A UMA ESPIRITUALIDADE ECOLÓGICA: POR UMA CONVERSÃO NECESSÁRIA
Authors: Lustosa Lopes Antonio de Lisboa , Xavier de Carvalho Magno
Published: November 2024

O artigo propões o problema da urgência de uma espiritualidade ecológica para promover uma humanidade integrada a tudo que existe, num empenho de cuidado pela Casa Comum. Com esta perspectiva, busca reconhecer o principal desafio a esta espiritualidade e aduz o paradigma predatório engendrado pelo paradigma tecnocrático como necessário de ser suplantado por um novo estilo de viver de comunhão universal na diversidade. Para tanto toma-se as ideias de Ailton Krenak e Papa Francisco como pistas importantes para engendrar esta espiritualidade ecológica que se sustenta numa cosmovisão de que tudo está interligado e que a base de sustentação da vida é a própria de vida de tudo que existe em toda sua intensidade. Da percepção duma urgência ao irrompimento de uma proposta de espiritualidade que pretende seja ressoada por toda a terra em vista duma verdadeira e efetiva ecologia integral.
ESPIRITUALISMOS: UMA PERSPECTIVA PLURAL E RICA DAS ESPIRITUALIDADES NÃO CRISTÃS
Authors: Signates Luiz , Teixeira de Moraes Ângela , Teixeira Gismair Martins
Published: November 2024

Este dossiê significa algo mais do que um mero esforço de tematização de uma área relevante nas ciências da religião. Sua proposição, desde o início, foi movimentada por uma preocupação teórico-epistemológica específica, que neste momento pretendemos destacar, para que os autores e leitores da Caminhos possam compreender o sentido do que entendemos como sendo o espiritualismo brasileiro e internacional.
Desarrollo sostenible, calidad de vida en el entorno rural y el turismo en tierra del Quijote
Authors:   Universidad de Castilla-La Mancha, López Ruiz Víctor Raúl , Nevado Peña Domingo
Published: November 2024

Este libro recoge los documentos del VI Congreso Nacional Cervantino y del Congreso de Investigación para el Reto Demográfico (ISEN_RED24), ), junto con nueve investigaciones innovadoras de estudiantes de la UCLM sobre despoblamiento y el medio rural desde una perspectiva económica y social. Las ponencias, por su parte, abordan el problema desde la economía circular, la empresa innovadora 4.0, el papel de las políticas de mayores y las áreas rurales inteligentes como zonas objetivo de alta calidad de vida.
Histerectomía subtotal vía vaginal con preservación de anillo cervical y suspensión del muñón cervical a ligamento sacroespinoso en mujeres con prolapso genital. Cohorte de expuestos
Authors: Machado Bernal Jaime Andrés , Lozada Ríos Andrea , Gómez Castro Armando Rafael
Published: November 2024

Objetivos: hacer una aproximación a la seguridad y eficacia a corto plazo de la histerectomía vaginal con preservación de cuello uterino en pacientes con prolapso genital estadios II a IV.
Materiales y métodos: estudio descriptivo tipo serie de casos. Se incluyeron mujeres con prolapso genital estadios II a IV, con indicación de histerectomía vía vaginal, con citología cervicovaginal negativa para malignidad, que fueron sometidas a histerectomía subtotal vía vaginal, con suspensión del muñón cervical al ligamento sacro-espinoso, del 1 de junio al 31 de diciembre de 2023 en una clínica general de alta complejidad. Se analizaron variables sociodemográficas y complicaciones a los seis meses del posoperatorio. Se presenta la técnica quirúrgica y se realiza análisis descriptivo y la exposición quirúrgica de la técnica con suspensión del muñón cervical al ligamento sacro-espinoso.
Resultados: en el periodo descrito consultaron 10 pacientes, de las cuales ocho cumplieron los criterios de inclusión. La duración media del procedimiento quirúrgico fue de 133 min. El sangrado tuvo una media de 200 cc. Una paciente requirió uso de analgésico para el dolor neuropático periférico tipo pregabalina, con lo que se logró adecuado manejo del dolor posoperatorio. No se presentaron otras complicaciones intraoperatorias o posoperatorias. No hubo recurrencia de prolapso a los seis meses de evaluadas las pacientes.
Conclusiones: la histerectomía subtotal vía vaginal con suspensión del muñón cervical al ligamento sacro-espinoso es una técnica de reparación quirúrgica que podría ser considerada para el manejo del prolapso uterino. Se requieren estudios aleatorizados que comparen esta técnica con otras alternativas de manejo para evaluar su eficacia a largo plazo y su seguridad.
A tragic case of filicide in the setting of neuropsychiatric sequelae of systemic lupus erythematosus
Authors: Human Allison , Armstrong Bridget , Subramaney Ugasvaree
Published: November 2024

Filicide, the deliberate killing of a child by a parent, is a rare offence but one that provokes high emotional reactions in almost everyone. Certain factors, such as psychiatric symptoms and social stressors, have been identified as increasing the risk for filicide. The neuropsychiatric complications of systemic lupus erythematosus, such as seizures, mood symptoms, and psychosis, can promote these factors, and health professionals must be vigilant in identifying those parents at risk. In this very unfortunate situation, we present the case of a mother who killed two of her children in the context of seizures, depression, and psychosis. The intricacies of neuropsychiatric sequelae of systemic lupus erythematosus are highlighted.
D-complete Single Axioms for the Equivalential Calculus with the rules D and R
Authors: Czakon Marcin
Published: November 2024

Ulrich showed that most of the known axiomatisations of the classical equivalence calculus (EC) are D-incomplete, that is, they are not complete with the condensed detachment rule (D) as the primary rule of the proof procedure. He proved that the axiomatisation EEpEqrErEqp, EEEpppp by Wajsberg is D-complete and pointed out a number of D-complete single axioms, including one organic single axiom. In this paper we present new single axioms for EC with the condensed detachment and the reversed condensed detachment rules that form D-complete bases and are organic.
«Pachamama no te cuido»
Authors: Avalo Ana Valeria , Duran Valeria Vanesa
Published: November 2024

El objetivo de este artículo es analizar la institucionalidad indigenista en articulación con las políticas neoextractivistas en Jujuy, Argentina, entre los años 2015 y 2022. Específicamente, estudiamos la relación de la Secretaría de Pueblos Indígenas con otras esferas del Estado provincial y con las comunidades indígenas. Abordamos tres casos: la sanción de la Ley N° 5915, la creación de la Policía Intercultural y el proyecto de instalación de una Zona Franca en la Quiaca Vieja. Retomamos una metodología cualitativa y utilizamos como técnica de construcción de datos la revisión documental, entrevistas y testimonios de fuentes secundarias. Nuestro marco teórico recoge perspectivas críticas sobre el neoindigenismo y el neoextractivismo, así como aportes del pensamiento político indio-indígena. Sostenemos como hipótesis que tanto la política neoindigenista como la política neoextractivista legitiman y desarrollan la actual matriz económico-productiva jujeña. Estudiamos las relaciones entre la institucionalidad indigenista y los ámbitos jurídico, económico y de seguridad estatal que contribuyen a la profundización del neoextractivismo. Los resultados de esta investigación aportan a los debates en torno al indigenismo en Argentina, al profundizar el estudio de una experiencia contemporánea a nivel subnacional.
A systematic review of technology-enhanced problem-based learning in the 21st century
Authors: Amin Adam Aliathun
Published: November 2024

Problem-based learning and innovation are instruments that help the abilities expected to foster 21st-century abilities. This has set off enormous advancements in instructive exploration connected with Problem-based learning and innovation. This content examination concentrates on plans to efficiently dissect research patterns in problem-put-together learning and innovation-based concerning articles distributed in global diaries. In light of the laid-out consideration rules, 20 articles were gathered for examination utilizing the Paper Arrangement Structure (PCF) instrument. The aftereffects of the examination showed the strength of acquiring and moving abilities points, oddity-themed, with experimental plan strategies. The most widely recognized reconciliation designs were connected with consensus. Consequently, it is important to lead different problem-put-together learning and innovation studies concerning other possible issues to assist instructive organizations with creating HR that can contend in the 21st.
Keywords: Problem-Based Learning, technology, 21st century
Speaking Skills Problems Encountered By Non-Native Arabic Learners At Universities In Northeast China
Authors: Gu Bingxin , Muin Ismail Wail
Published: November 2024

Speaking skills are critical in second language acquisition. This study investigates the most common speaking skills problems among non-native Arabic learners in universities in Northeast China and the differences between speaking skills problems based on gender and academic level. A quantitative research design was adopted. It used the questionnaire to collect data. The sample of this study included 104 Chinese students who learn Arabic from two universities in Northeast China. The results indicate that the most common problems with Arabic speaking skills are a lack of vocabulary, opportunities to meet native Arabic speakers, fear of mistakes, teacher-centered classes, and the teacher using too many students’ native languages in the classroom. Besides that, the results show no statistically significant difference in Arabic speaking skills problems based on gender. However, the findings show statistically significant differences in Arabic speaking skills problems based on the academic level. The learners of the second year have more Arabic speaking skills problems than the learners of the first year, and the learners of the third year also have more Arabic speaking skills problems than the learners of the first year. According to the findings, the study suggests recommendations for Arabic learners, instructors, and policymakers in universities in non-Muslim gathering areas in Northeast China.
The Effectiveness Of A Proposed Educational Unit Based On The Comprehensive Language Approach In Developing Reading Skills Among Foreign Learners At The Intermediate Level/ فاعلية وحدة تعليمية مقترحة قائمة على المدخل الكلي للغة في تنمية مهارة القراءة لدى الدارسين الأجانب في المستوى المتوسط
Authors: Abdur Razaq Kharashi Nasirudeen , Mohd Noor Siti Salwa Binti
Published: November 2024

This study aimed to determine the effectiveness of a proposed educational unit in light of the Whole Language approach in developing some Arabic language arts skills among foreign learners at the intermediate level. To achieve this goal, the researcher built research tools consisting of indicators of necessary Arabic language arts skills for foreign learners at the intermediate level. Method: a pre-and post-test will be used to develop appropriate Arabic language arts skills among foreign learners at the intermediate level. The study sample consisted of thirty male and female students from the preparatory year program at the Language Center of the Faculty of Languages and Communication at Sultan Zainal Abidin University, Kuala Terengganu, Malaysia. The researcher adopted the descriptive and quasi-experimental method when applying the study tools. After experimenting with the study tools and analyzing the results (data) of the pre-and post-applications statistically using statistical packages system of social sciences to calculate percentages, relative weight, and standard deviation, the study reached results, the most important of which are: (1) The effectiveness of the proposed educational unit built in the light of whole approach in developing Arabic language arts skills as a whole. (2) The effectiveness of the proposed educational unit is built in the light of the whole approach to developing language skills in each skill area separately. According to its results, the study also suggested some recommendations and proposals, the most important of which are: (1) The need to adopt the Whole language approach in developing the reading skills of Arabic language learners, whether native or non-native speakers. (2) The importance of sensitizing Arabic language teachers to the importance of this approach and providing training to familiarize them with the application of this approach. (3) This approach is used in teaching other language skills because it positively impacts the teaching of the Arabic language.
The Influence Of Mu'tazilah According To Al-Zamakhshari On The Understanding Of Hadith As Arabic Literature In Tafsir Al-Kashshaf As An Example/ تأثير الـفكر الاعتزالي عند الـزمخشري في فَهْمِ الـحديث في تفسيره الـكشاف نموذجًا
Authors: Karabelli M. Kamel M. Salim
Published: November 2024

There are still errors in responding to Arabic literature, especially the hadith of the prophet, starting from the wrong assessment of the hadith, then the fragmented understanding of the hadith based on abstract rational logic, ignoring the guidance of scholars in their context with other texts, or underestimating their scientific guidance and ending with making the hadith as an argument for the intellectual or doctrinal school of thought that is very influential in responding to the hadith of the prophet. This study aims to clarify Al-Zamakhshari's position on the hadith of the prophet in terms of understanding, conclusions, and assessments through his revealing interpretation. The research method used is the inductive method. When tracing the hadiths Al-Zamakhshari mentioned in his tafsir, a descriptive approach is used to explain Al-Zamakhshari's position on them, and then a critical approach is used. By presenting this, Al-Zamakhshari failed to understand, direct, and decide on the hadiths; in this case, he differed from the trusted great imams. The result is That al-Zamakhshari is one of the scholars influenced by the Mu'tazilah in responding to hadith, as can be seen from the adjustment of hadiths in accordance with Mu'tazilah.
Analysis of the Implementation of Interpretation of Financial Accounting Standards (ISAK) 35
Authors: Lailatul Ulfiyah  , Djalaluddin Ahmad
Published: November 2024

Tujuan utama dari penelitian ini adalah untuk memahami dan menganalisis penerapan ISAK 35 dalam pelaporan keuangan Pondok Pesantren. Penelitian ini menggunakan metode deskriptif kualitatif dengan jenis pendekatan studi kasus. Hasil penelitian ini menunjukkan bahwa laporan keuangan Pondok Pesantren Sabilul Muttaqin Mojokerto tidak disusun berdasarkan ISAK 35 karena bendahara Pondok Pesantren tidak mengetahui dan mempelajari laporan keuangan yang sesuai dengan lembaga nirlaba Dengan demikian, catatan hanya mencakup transaksi tunai masuk dan keluar. Selain itu, latar belakang pendidikan bendahara tidak menekankan masalah keuangan. Namun, setelah diteliti, laporan keuangan pesantren tersebut sesuai dengan prinsip ISAK 35. Ini termasuk pencantuman laporan laba rugi komprehensif, laporan arus kas, laporan posisi keuangan, laporan perubahan aset bersih, dan CALK (Catatan atas Laporan Keuangan), sehingga memungkinkan pengumpulan yang lebih mudah dan lebih tepat pengumpulan informasi keuangan terkait Pondok Pesantren Sabilul Muttaqin Mojokerto.
Persepsi Etis Penghindaran Pajak: Tinjauan Pengaruh Perilaku Keputusan Investasi dan Love of Money
Authors: Abdillah M. Riduan , Putriana Astia , Hadiani Yasir
Published: November 2024

Penelitian ini bertujuan menemukan bukti empiris mengenai pengujian pengaruh perilaku keputusan investasi dan love of money terhadap persepsi etis penghindaran pajak dalam rangka menjawab tantangan fenomena edukasi investasi dan entrepreneur di tengah kemajuan teknologi dan informasi khususnya bagi para generasi millenial yang didominasi berasal dari Perguruan Tinggi. Penelitian ini berfokus pada pengujian sikap/perilaku keuangan. Maraknya risiko investasi berbanding lurus dengan perilaku etis atau non etis perpajakan. Metode penelitian ini adalah metode kuantitatif. Populasi penelitian ini adalah mahasiswa/i Program Studi Akuntansi/Ekonomi pada Perguruan Tinggi di Kalimantan Selatan. Teknik pengambilan sampel di penelitian ini menggunakan metode purposive sampling, didapat sebanyak 272 responden. Hasil penelitian menunjukkan bahwa perilaku keputusan investasi tidak berpengaruh terhadap persepsi etis penghindaran pajak. Selain itu, love of money berpengaruh terhadap persepsi etis penghindaran pajak. Temuan empiris ini dapat menjadi acuan dalam mengidentifikasi tantangan dalam rangka meminimalisasi penghindaran pajak.
Examen des possibilités forestières et de l'industrie du bois dans les pays du Sud-Est Asiatique
Authors: Anguilé A.G.
Published: November 2024

Après quelques remarques générales sur les pays d'Asie du Sud-Est possédant des forêts humides (300 millions d'habitants en 1975, 200 millions d'hectares de forêts), l'auteur passe en revue les différents pays producteurs :La Fédération de Malaisie (23,5 millions d'hectares de forêts), Malaisie occidentale, Malaisie orientale, Sarawak et Sabah.- L'Indonésie (122 millions d'hectares de forêts) comprenant principalement Sumatra, Kalimantan, les Célèbes (Sulawesi), les Moluques et l'Irian occidental.- Les Philippines (14 millions d'hectares de forêts).- la Birmanie (38,8 millions d'hectares de forêts)- la Thaïlande (24 millions d'hectares de forêts).Une deuxième partie est consacrée aux marchés de consommation :- Les pays proches : Japon, Australie, Chine, Corée du Sud, Singapour, Taïwan, Hong Kong.- Pays de la Communauté économique européenne.
UE y conflictos de leyes internos
Authors: Álvarez Rubio Juan José
Published: November 2024

El ordenamiento jurídico español se ubica en el grupo de los calificados como complejos o plurilegislativos, caracterizado por la convivencia de diversos sistemas legislativos territoriales y por la presencia en su seno de conflictos internos de carácter interregional e interlocal. La pluralidad interna es también objeto de creciente atención y regulación normativa en el plano europeo y en el bloque normativo convencional/internacional. Urge acometer la reforma este sector de nuestro ordenamiento, teniendo presente una perspectiva basada en la obligada hibridación de tres dimensiones (constitucional, jurídico-privada europea e interna) para poder fundamentar el establecimiento de un conjunto coherente de normas que proporcionen seguridad jurídica al sistema.
La excepción de interés nacional en el DIPR español actual
Authors: Arenas García Rafael
Published: November 2024

La excepción del interés nacional se encuentra recogida en múltiples legislaciones y también en instrumentos internacionales. En este trabajo se examina el papel que cumple, qué condiciones han de darse para que opere y cómo se regula tanto en el Reglamento Roma I como en el DIPr español de origen interno. Se analiza también la reciente reforma del art. 10.8 del CC, que ha transformado de forma profunda la regulación de la excepción en el DIPr español de fuente interna.
¿In medio virtus? A favor del canon jurisprudencial objetivo del “consumidor medio” para el control de transparencia de las cláusulas no negociadas
Authors: Cámara Lapuente Sergio
Published: November 2024

Desde su misma génesis jurisprudencial, en 2013 y 2014, el control de transparencia de las cláusulas no negociadas ha sido configurado con carácter abstracto y objetivo. Así como el Tribunal de Justicia de la Unión Europea (TJUE) no ha abandonado ese parámetro, fundado en el “consumidor medio” y no en el consentimiento del concreto contratante, el Tribunal Supremo español (TS), en los últimos años ha denegado protección por ese control a “personas con conocimiento experto” en un específico tipo de contrato (frecuentemente préstamos hipotecarios), como ha ocurrido con ciertos empleados de entidades financieras y abogados especializados. Este ensayo examina el origen de la noción de “consumidor medio” y su trasplante al ámbito de la interpretación de la Directiva sobre cláusulas abusivas, traza las diversas etapas, tendencias y divergencias en la jurisprudencia del TJUE y del TS y ofrece nuevos argumentos sobre la conveniencia de mantener en este ámbito ese estándar objetivo, en línea con la interpretación transversal del concepto en varias Directivas de protección de los consumidores que recientemente está manteniendo el TJUE. Asimismo, a la luz de las conclusiones presentadas en 2024 por los Abogados Generales del TJUE en dos importantes asuntos pendientes de fallo (el asunto C-450/22, Caixabank et al., y el asunto C-646/22, Compass Banca), esta contribución analiza si la noción de consumidor medio, racional y proactivo, podría modularse con las teorías del análisis socio-económico del comportamiento humano para integrar ciertas vulnerabilidades en el estándar medio.
Cambio de vecindad civil en el sistema plurilegislativo español
Authors: Egusquiza Balmaseda M.ª Ángeles
Published: November 2024

La vecindad civil ha sido históricamente el eje central de la resolución de los conflictos interregionales en España. De ella se ha hecho depender la ley civil aplicable a la sucesión “mortis causa” del nacional español. La consideración de la vecindad civil como norma de conflicto, de competencia exclusiva del Estado -art. 149.1.8 CE-, ha mantenido abierto un debate, ya clásico, que resulta relevante en el sistema plurilegislativo civil español. En particular, se advierte sobre las reglas del art. 9.8 del CC, norma que evidencia la falta de neutralidad y paridad en el conflicto móvil sucesorio cuando entran en liza los distintos Derechos civiles que conviven en España. La reflexión sobre la adecuación a la realidad social de la vigente normativa conflictual del Código civil, el alcance efectivo de la voluntad testamentaria y la demandada renovación legal en esta materia son las vías sobre las que se asienta el presente trabajo.
La exención de responsabilidad de las plataformas de comercio electrónico por infracciones de la propiedad industrial
Authors: García Vidal Ángel
Published: November 2024

El presente trabajo examina la exención de responsabilidad en la que pueden ampararse los titulares de plataformas de comercio por los productos que comercializan en ella terceras personas. A tal efecto, se estudia el régimen inicialmente establecido en la Directiva de comercio electrónico y su interpretación por el Tribunal de Justicia, para posteriormente exponer el proceso de intensificación de la responsabilidad de las plataformas, que ha encontrado su última manifestación en el reciente Reglamento de Servicios Digitales (Digital Services Act).
Attuazione delle sentenze della Corte EDU e tenuta del giudicato civile in Italia
Authors: Grassi Michele
Published: November 2024

Se l’ordinamento italiano prevede da tempo la possibilità di rimuovere gli effetti pregiudizievoli delle decisioni penali di condanna adottate in violazione dei diritti umani, più recente è l’introduzione di un motivo di revocazione della sentenza civile per contrasto con la CEDU. Il nuovo meccanismo revocatorio presenta, tuttavia, un ambito di applicazione particolarmente ristretto, cosicché, in molti casi, non è ancora possibile ottenere la riapertura del procedimento nazionale sebbene una sentenza della Corte di Strasburgo abbia accertato l’incompatibilità del giudicato civile con i diritti umani tutelati dalla CEDU. Il presente studio si interroga, allora, sull’esistenza di un obbligo di riapertura dei procedimenti civili nazionali quale conseguenza dell’obbligo di dare esecuzione alle sentenze della Corte EDU, di cui all’art. 46 CEDU, letto alla luce del rapporto di responsabilità internazionale che sorge in conseguenza di un illecito.
Ámbito y condiciones de aplicación en la práctica del foro de competencia judicial internacional contenido en el artículo 10 del Reglamento 2201/2003
Authors: Herranz Ballesteros Mónica
Published: November 2024

La interpretación del foro de competencia judicial internacional contenido en el artículo 10 del Reglamento 2201/2003 es el objeto central de este estudio. El artículo 10 permite, de un lado, mantener la competencia judicial internacional de las autoridades de la residencia del menor anterior a su traslado, posibilitando, de otro lado, la transferencia de la misma hacia las autoridades donde el menor ha sido desplazado o retenido cuando se cumplan las condiciones previstas en el citado precepto. Su aplicación por las autoridades judiciales es controvertida por lo que en este trabajo vamos a profundizar tanto en la concreción del ámbito espacial de aplicación del precepto, como las condiciones o requisitos para su funcionamiento. Este análisis, a través de la jurisprudencia del TJUE, permitirá aclarar su correcta aplicación en la práctica.
La eficacia del third party release en supuestos transfronterizos
Authors: Torralba Mendiola Elisa
Published: November 2024

El artículo 652,2 de la Ley Concursal prevé que los efectos del plan de reestructuración de una sociedad de un grupo se pueden extender a las garantías personales o reales prestadas por cualquier otra sociedad del mismo grupo no sometida al plan de reestructuración, cuando la ejecución de la garantía pueda causar la insolvencia de la garante y de la propia deudora. Una regla similar se contiene en el artículo 596,3 de la misma Ley para los casos de comunicación de apertura de negociaciones. La eficacia de estas reglas se ve puesta en entredicho en situaciones transfronterizas, en las que las disposiciones de la Unión Europea y/o las reglas en materia de reconocimiento del país en el que este deba producirse pueden establecer ciertos obstáculos, derivados fundamentalmente de su comprensión de la extensión de la competencia de las autoridades españolas. Si bien la Ley Concursal permite salvar la eficacia de los artículos citados en ciertas situaciones, no la garantiza en todos los casos.
La imposición de precios de reventa en el Derecho de la competencia europeo
Authors: Velasco San Pedro Luis Antonio
Published: November 2024

El objeto de este artículo es la imposición de precios de reventa en el Derecho de la competencia europeo. En primer lugar, se estudian los efectos anti y procompetitivos de esta práctica, y la evolución de su regulación en los Estados Unidos, como modelo de referencia, hasta llegar a la sentencia Leegin. Posteriormente se analiza la situación en la UE, partiendo de cómo se ha ido considerando históricamente la cuestión en los reglamentos de exención por categorías y por la praxis de la Comisión y la jurisprudencia del Tribunal de Justicia. Finalmente, se estudia el estado actual de la cuestión en el Reglamento 2022/720 sobre acuerdos verticales, la Comunicación de la Comisión de 2022 sobre Directrices relativas a las restricciones verticales y la reciente sentencia del Tribunal de Justica en el asunto Super Bock.
Grape berry mycobiota and its contribution to fresh mushroom aroma off-odour in wine
Authors: Destanque Adrien , Picot Adeline , Pensec Flora , Pawtowski Audrey , Rolland Nolwenn , Treguer-Fernandez Sylvie , Debaets Stella , Guérin Laurence , Mercier Laurence , Coton Emmanuel , Hervé Marion , Coton Monika
Published: November 2024

Grape berry mycobiota is a complex and diverse ecosystem that is constantly evolving during the different berry ripening stages of vines, as well as in musts and wines, which can ultimately impact wine sensorial properties and thus overall product quality. To better characterise the role of this mycobiota in wine off-odours, we studied for the first time changes in Pinot Noir and Meunier grape and must mycobiota and carried out sensorial analyses in the resulting wines, with a focus on fresh mushroom aroma. Grapes from three berry ripening stages, fruit set, veraison and harvest, were collected without sorting bunches from 31 parcels, then laboratory-scale grape crushing was performed to obtain musts, followed by micro-winemaking. For all sample types, both culture-dependent and -independent strategies were used to decipher both species and genus level mycobiota composition. After the winemaking process, sensorial analyses detected 9 laboratory wines with fresh mushroom aroma off-odours. Musts that generated these spoiled wines contained higher total fungal counts, especially Penicillium spp., compared to other musts. A total of seven Penicillium species, including one unidentified Penicillium sp., was detected using the culture dependent approach; this genus represented up to 100 % of all fungal counts in musts linked to FMA wines. Fungal interactions inferred using co-occurrence networks revealed positive interactions between Vishniacozyma, Cladosporium and Penicillium in musts, indicating the possible implication of these three genera in FMA production. Negative interactions were observed in musts between the two yeast genera, Starmerella and Pichia, with Penicillium, Botrytis, Vishniacozyma and Cladosporium, as well as between Metschnikowia with Botrytis and Vishniacozyma. Starmerella, Pichia and Metschnikowia may thus be potential biocontrol candidates for use against Botrytis and Penicillium grape contamination.
Current Concepts in Orthobiologics for Achilles Tendon Injuries
Authors: Gopinatth Varun , Boghosian Tanya , Perugini Julia M. , Smith Matthew V. , Knapik Derrick M.
Published: November 2024

» Platelet-rich plasma and hyaluronic acid are low-risk and potentially high-reward treatments for Achilles tendinopathy, although clinical studies have yielded mixed results with questionable methodological quality

» Case series and reports have reported that bone marrow aspirate, stem cells, and amniotic membrane products can improve functional outcomes, alleviate pain, and facilitate return to sport and activities, but high-level evidence studies are lacking

» Exosomes are a promising novel biologic with laboratory studies showing improved collagen organization and cell proliferation, greater tendon mechanical properties, and prevention of extracellular matrix breakdown.

» Standardization of protocols with clear reporting is necessary for future studies evaluating orthobiologic therapies for Achilles tendon injuries
Assess of students’ Knowledge Concerning Effect of Lifestyle on Polycystic Ovary Syndrome
Authors: Hamid Samahir Sabri
Published: November 2024

Polycystic ovary syndrome (PCOS), also known as Stein-Leventhal syndrome, is an endocrine disorder that affects 15% to 20% of women of reproductive age and involves the presence of multiple follicular cysts on one or both ovaries. This study was conducted to assess the knowledge about PCOS, effects of lifestyle habits on PCOS and knowledge of diverse treatment methods to reduce the risks of the syndrome.180 female students from three colleges were participate a questionnaire include demographic information  of students and scientific questions   concerning PCOS, Among the 180 female students whose knowledge was evaluated about the effect of lifestyle on polycystic ovary syndrome, (32%) of the participants had a good knowledge rate, (53%) of them had a moderate knowledge rate, and (15%) had a poor knowledge rate.
Pilgrimage Tourism to Wali Tombs and Halal Destination Management Based on Sharia Values
Authors: Kusumaningtyas Menur , Ulfah Indar Fauziah
Published: November 2024

This study explores the relationship between pilgrimage tourism to Wali tombs and halal tourism, focusing on the integration of Sharia values in the management of religious destinations. In the context of East Java, this research examines the application of Sharia principles by site managers to maintain the sanctity and integrity of the sites, as well as its impact on the experience of Muslim tourists. The study uses a qualitative approach with a case study method. Data were collected through in-depth interviews with site managers, tourists, and local communities, along with direct field observations. The findings show that the application of Sharia management in site operations not only enhances tourist satisfaction but also strengthens the local economy and cultural preservation. However, the study also found a lack of understanding of Sharia values among some site managers. This research provides recommendations for site managers to create tourist destinations aligned with Sharia principles, supporting the growth of halal tourism in Indonesia. It is hoped that the results of this study can serve as a reference for developing policies on sustainable and responsible religious tourism.This study has several limitations, including the geographical scope limited to East Java and restricted access to all pilgrimage site managers. Therefore, the findings cannot be generalized to all religious tourism destinations in Indonesia. Further research covering a broader area is recommended to enrich the findings.
A Nonaxial-Type Swirling Cavitating Nozzle for Exploiting Natural Gas Hydrate
Authors: Chen Xiaoping , He Zhipeng , Liu Guangli , Ao Xin
Published: November 2024

Natural gas hydrates (NGHs) have garnered widespread attention in the new energy sector, owing to their efficient and clean combustion properties. NGHs are ice-like substances formed by methane and water under high-pressure and low-temperature conditions, abundantly deposited in seabeds and frozen soil of highlands on Earth. However, the rock shelves of NGH reservoirs are mostly fragile and sparsely colloidal. Traditional mechanical mining methods can easily cause rock-shelf collapses, leading to mining accidents. Long-term indoor experiments and pilot mining projects have shown that cavitating nozzles can provide a feasible solution to the problem of efficient mining of NGHs.

To further improve the efficiency of cavitating nozzle mining for NGHs, we have optimized and designed a nonaxial-type swirling cavitating nozzle (NASCN) based on traditional swirling cavitating nozzles (SCNs). Both numerical simulations and indoor experiments have verified the higher mining performance of this nozzle.

In the numerical simulation experiments, we analyzed the cavitation performance, erosion performance, and energy consumption characteristics of different cavitating nozzles using the mixture multiphase flow model and the renormalization group (RNG) k-ε turbulence model. In the indoor experiments, we utilized a jet erosion experimental device for NGHs to analyze the erosion effects of different cavitating nozzles on hydrate samples. The results of these experiments indicate that the NASCN reduces energy consumption by 12% compared with traditional nozzles when there is little difference in cavitation performance and erosion performance. Moreover, under similar energy consumption, the NASCN improves erosion efficiency by 35.2% compared with traditional nozzles. These results demonstrate that the NASCN has good application value in the mining engineering of NGHs.
The Impact of Sedimentology and Diagenesis on the Hydraulic Flow Units Quality of Lower Cretaceous Aradeiba-Bentiu Sequence Reservoir Rocks of Laloba Oilfield, SE Muglad Basin, Sudan
Authors: Bokhari Abdaseed K. , Ehinola Olugbenga , Boboye Olugbenga , Abdullatif Osman
Published: November 2024

The Muglad Rift Basin in Sudan has been discovered to have two significant main hydrocarbon reservoirs: the Aradeiba Formation and the Bentiu Formation. This study endeavours to investigate the impact of diagenesis and depositional lithofacies on reservoir characteristics to improve prediction and deepen the current understanding of reservoir quality. However, this research incorporates fundamental characterisation and examination of cored intervals of the Laloba Oilfield in the Muglad Basin. An analysis of three cored intervals of a well in the Laloba Oilfield in the Muglad Basin of Sudan comprised petrographic, petrophysical, and diagenetic aspects, thereby providing in-depth insight into the reservoir properties of the analysed intervals. Moreover, gamma-ray well log analysis of seven wells performed to emphasise the facies groups. Six principal lithofacies have been identified: fine laminated sandstone (Fl); siltstone and mudstone, ripple marked siltstone (Sr); trough cross-bedded sandstone (St); planar cross-bedded sandstone (Sp); massive sandstone (Sm); and intra-formational conglomerate-size mud clast (Sco). The lithofacies observed exhibit characteristics that reflect a fluvial depositional environment comprising both channel-fill and overbank deposits. The average porosity and permeability values were 24.9% and 1286.5 mD, respectively. Furthermore, the entire studied interval was classified into three hydraulic flow units (HFUs) based on cross plots of the reservoir quality index (RQI), the normalised porosity index (NPI), and the flow zone indicator (FZI). The good, intermediate and bad reservoir quality types are respectively corresponding to HFU-1, HFU-2 and HFU-3. The reservoir quality of the sandstone units from Aradeiba (upper part, Core-1) and Bentiu (Core-3) are grouped under HFU-1, which is greatly affected by the dissolution of k-feldspar particles, leading to enhanced porosity and permeability (visual porosity). However, the HFU-2 and HFU-3 samples are characterised by high cementation of authigenic kaolinite and high mechanical compaction (point grain contact, long grain contact, and concave-convex grain contact), which have lowered and degraded the reservoir properties. Generally, integrated core data analyses provide insight into the impact of depositional and diagenetic processes on reservoir quality, thus improving reservoir quality prediction.
Love Thy Neighbor? Exploring Gastroenterology Attitudes Towards Endometriosis Screening
Authors: Luo Yuying , Wang Xiao Jing , Keefer Laurie A. , Simons Madison
Published: November 2024

Endometriosis is a chronic painful condition affecting 10% of reproductive-aged women with a high prevalence of overlapping gastrointestinal symptoms. There is a significant diagnostic delay for endometriosis and current screening practices for endometriosis in gastroenterology clinic populations have not been evaluated. 112 gastroenterology providers (57.5% females, 64.3% physicians) completed an anonymized exploratory survey (40.1% response rate). Most respondents (59.4%) currently do not screen for endometriosis, but the majority (72.1%) reported they would be “extremely likely” or “somewhat likely” to screen for endometriosis after being presented with data on the high prevalence of chronic GI symptoms in patients with endometriosis.
Evaluation of Conventional Techniques and Ultrasonic Extraction of Some Plant by-products as Eco-friendly Antimicrobial Agents for Food Pathogens and Spoilage Microorganisms
Authors: Ali Amal Mohamoud , Latif Souzan Saad , Abdel-Aleem Waleed Mohamed , Kenawi Mohamed Naguib
Published: November 2024

Plant byproduct extracts are obtained by extracting bioactive compounds from various plant byproduct sources, such as leaves, seeds and peels. These sources are rich in bioactive compounds such as total phenols (TPC), total flavonoids (TFC), and antioxidant capacity (TAC). These compounds have antioxidant and antimicrobial effects; hence, they are widely used as natural preservatives. The antimicrobial activity of organic extracts of some plant byproducts was determined via the disk diffusion method. The results revealed that the solvent (70%, 50% ethanol and water extraction) and extraction methods (conventional and ultrasonic extraction) significantly affected the amount of photochemical compounds (phenols, total flavonoids and total antioxidants) and antioxidant activity. Compared with the conventional method, ultrasonic extraction clearly affected antimicrobial activity, as it was more effective against Fusarium solani, Penicillium digitatum, E. coli and Erwinia cartov in most of the extracts. Pomegranate peels subjected to ultrasonic extraction resulted in the greatest inhibitory effect on the diameter of E. coli (31.5 mm) and Erwinia cartov (29.5 mm) in addition to fungi (Penicillium ssp., 31.5 mm). However, the 50% ultrasonic ethanolic extract of Sidr leaves was highly effective against F. solani. Through this study, it became clear that the extraction method and the solvent used led to an increase in antimicrobial activity, and pomegranate peel extraction resulted in a higher inhibition rate than did the chemical preservatives used in the study. Therefore, plant extracts can be used as safe alternatives to chemical preservatives.
Comprehensive Source Tracing and Process Supervision of Coating Industrial Wastewater Using Integrated Water Quality Parameters and Fluorescence Spectroscopy
Authors: Yuan Jinlong , Chen Shiying , Ge Baoxin , Cui Mingyang , Wong Yongjie , Qi Yuanfeng , Ge Yanhong , Hao Aimin , He Kai
Published: November 2024

Rapid industrialization has led to centralized industrial parks, particularly for heavily polluting industries like coatings, which generate significant volumes of hazardous wastewater. Effective influent management and process monitoring are essential for the stable operation of wastewater treatment plants in these parks. This study collected samples from factories in a coating industrial park and its treatment plant to characterize water quality. Fluorescence spectra were analyzed using Parallel Factor Analysis (PARAFAC) to identify specific components. A characteristic fluorescence peak at Ex/Em = 350/425 nm was detected, indicating the presence of aromatic hydrocarbons. Conventional treatment was ineffective in removing these substances, while ozone-catalyzed oxidation effectively degraded them. UV254 showed significant correlations with the biological index (BIX) (r=-0.52) and fluorescence component C1 (r = 0.85), suggesting its potential as a pollutant marker. Component C4, identified as lignin-like, is typical of coating industry materials. These findings demonstrate the potential of fluorescence spectroscopy and PARAFAC for tracing wastewater sources and monitoring pollutant degradation in industrial treatment plants.
Unveiling Unique Expression Patterns of D20S16 Satellite DNA in Human Embryonic Development
Authors: Hu Yajie , Mizuguchi Kenji , Hashimoto Kousuke
Published: November 2024

Background: Satellite DNA plays a crucial role in maintaining chromosomal stability and gene regulation. However, its specific functions during early embryonic development are not fully understood. In this study, we investigate the expression patterns and regulatory mechanisms of D20S16 satellite DNA during critical stages of human embryogenesis by integrating the complete human genome reference (T2T-CHM13) with RNA-seq data.
Results: Our comprehensive analysis reveals that D20S16 exhibits high expression levels in early developmental stages, followed by a significant decline as development progresses. We identified 20 distinct D20S16 elements in the human genome and found that only two elements, located on chromosome 20, are transcriptionally active during embryogenesis. Comparative analysis with macaque data further demonstrates that D20S16 is minimally expressed in macaque embryos, which have shorter and fewer repeat units compared to humans.
Conclusion: These findings suggest that D20S16 plays a unique regulatory role in human embryonic development, with its expression being potentially linked to specific chromosomal locations. This study provides new insights into the role of satellite DNA in early development and sets the foundation for future research into its function and evolutionary significance.
Targeted degradation of host messenger RNA by a bacterial pathogen
Authors: Hartland Elizabeth , McCaffrey Kathleen , Sivaraman Hariharan , von Ameln Joshua , Wibawa Raissa , Li Pengfei , Pidot Sacha , Pasricha Shivani , Ng Garrett , Garama Daniel , Driel Ian van , Garbi Natalio , Wong Wilson
Published: November 2024

Post-transcriptional processing and modification of messenger RNA (mRNA) regulates gene expression in eukaryotes by dictating the stability, localisation and translation of newly synthesised transcripts 1. These epitranscriptomic events are coordinated by an extensive network of RNA-binding proteins 2,3. Here we observed that the bacterial pathogen, Legionella pneumophila, caused the selective degradation of host cellular mRNAs encoding factors involved in glycolysis and related metabolic pathways. Screening of a library of L. pneumophila deletion mutant strains revealed a single effector protein, LegC4, that mediated the post-transcriptional degradation of host mRNAs encoding key glycolytic enzymes, thereby suppressing host glycolysis during infection. Using CLIP-seq and complementary methods, we observed that LegC4 bound to mature processed host mRNA recognising a guanine (G)-rich motif that was overrepresented within mRNAs targeted for degradation. In vitro activity assays showed that LegC4 harboured intrinsic RNase activity and structural determination of a catalytically inactive mutant of LegC4 in complex with single-stranded RNA revealed a unique RNA-binding domain 4. The selective binding and degradation of host mRNA by LegC4 reveals a previously undescribed mechanism of bacterial effector protein activity targeting the host epitranscriptome.
Natural Deep Eutectic Solvents Impregnated Graphene Oxide as an effective adsorbent for Dispersive Solid Phase Microextraction of Cd(II) From Environmental Samples
Authors: OZALP Ozgur , KORI Abdul Hameed , Soylak Mustafa
Published: November 2024

A sensitive and selective dispersive solid phase microextraction procedure was developed by synthesizing NaDES impregnated Graphene oxide nanocomposite (GO@NaDES) for the determination of trace amounts of cadmium prior to high-resolution continuum source flame atomic absorption spectrometry (HR-CS-FAAS) measurement. The detection limit, preconcentration factor, enrichment factor, and relative standard deviation were determined as 0.613 µg L− 1, 30, 30.3 and 4.0-5.5%, respectively. The method was successfully applied to natural and water samples and the amount of Cd was measured effectively. The d-SPME method developed will contribute to the literature as a practical, environmentally friendly and inexpensive method that can be performed in a short time of about 15 minutes, including analysis for Cd(II) analysis at the trace level in environmental water and food samples.
Salient Region-Aware Hashing with Interactive Channel Optimization for Fine-Grained Image Retrieval
Authors: Cao Congjun , Liao Kaiyang , Feng Wen
Published: November 2024

The fine-grained image retrieval task is challenging due to small inter-class and large intra-class variations, making it hard for hashing methods to distinguish subtle differences. Traditional algorithms often overlook detail in feature extraction, mapping similar images to different hash codes, while existing methods focus on dense regions and ignore other discriminative areas, lowering accuracy. Additionally, current approaches lack inter-channel correlation modeling, limiting feature aggregation. This paper proposes a hashing method based on salient region localization to capture fine-grained local features and an interactive channel transformation module to model inter-channel relationships. Experiments on four benchmark datasets show significant retrieval accuracy improvements over baselines, enhancing fine-grained image retrieval performance.