bluuebunny/crossref_metadata_2025 huggingface dataset:
Pterional versus superciliary keyhole approach: direct comparison of approach-related complaints and satisfaction in the same patient
Authors: Park Jaechan , Son Wonsoo , Kwak Youngseok , Ohk Boram
Published: March 2018

OBJECTIVE

The objective of this study was to evaluate and compare the level of patient satisfaction and approach-related patient complaints between a superciliary keyhole approach and a pterional approach.

METHODS

Patients who underwent an ipsilateral superciliary keyhole approach and a contralateral pterional approach for bilateral intracranial aneurysms during an 11-year period were contacted and asked to complete a patient satisfaction questionnaire. The questionnaire covered 5 complaint areas related to the surgical approaches: craniotomy-related pain, sensory symptoms in the head, cosmetic complaints, palpable cranial irregularities, and limited mouth opening. The patients were asked to rate the 5 complaint areas on a scale from 0 (asymptomatic or very pleasant) to 4 (severely symptomatic or very unpleasant). Finally, the patients were asked to rate the level of overall satisfaction related to each surgical procedure on a visual analog scale (VAS) from 0 (most unsatisfactory) to 100 (most satisfactory).

RESULTS

A total of 21 patients completed the patient satisfaction questionnaire during a follow-up clinic visit. For the superciliary procedures, no craniotomy-related pain, palpable irregularities, or limited mouth opening was reported, and only minor sensory symptoms (numbness in the forehead) and cosmetic complaints (short linear operative scar) were reported (score = 1) by 1 (4.8%) and 3 patients (14.3%), respectively. Compared with the pterional approach, the superciliary approach showed better outcomes regarding the incidence of craniotomy-related pain, cosmetic complaints, and palpable irregularities, with a significant between-approach difference (p < 0.05). Furthermore, the VAS score for patient satisfaction was significantly higher for the superciliary approach (mean 95.2 ± 6.0 [SD], range 80–100) than for the pterional approach (mean 71.4 ± 10.6, range 50–90). Moreover, for the pterional approach, a multiple linear regression analysis indicated that the crucial factors decreasing the level of patient satisfaction were cosmetic complaints, craniotomy-related pain, and sensory symptoms, in order of importance (p < 0.05).

CONCLUSIONS

In successful cases in which the primary surgical goal of complete aneurysm clipping without postoperative complications is achieved, a superciliary keyhole approach provides a much higher level of patient satisfaction than a pterional approach, despite a facial wound. For a pterional approach, the patient satisfaction level is affected by the cosmetic results, craniotomy-related pain, and numbness behind the hairline, in order of importance.
Fifty shades of gradients: does the pressure gradient in venous sinus stenting for idiopathic intracranial hypertension matter? A systematic review
Authors: McDougall Cameron M. , Ban Vin Shen , Beecher Jeffrey , Pride Lee , Welch Babu G.
Published: March 2018

OBJECTIVE

The role of venous sinus stenting (VSS) for idiopathic intracranial hypertension (IIH) is not well understood. The aim of this systematic review is to attempt to identify subsets of patients with IIH who will benefit from VSS based on the pressure gradients of their venous sinus stenosis.

METHODS

MEDLINE/PubMed was searched for studies reporting venous pressure gradients across the stenotic segment of the venous sinus, pre- and post-stent pressure gradients, and clinical outcomes after VSS. Findings are reported according to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines.

RESULTS

From 32 eligible studies, a total of 186 patients were included in the analysis. Patients who had favorable outcomes had higher mean pressure gradients (22.8 ± 11.5 mm Hg vs 17.4 ± 8.0 mm Hg, p = 0.033) and higher changes in pressure gradients after stent placement (19.4 ± 10.0 mm Hg vs 12.0 ± 6.0 mm Hg, p = 0.006) compared with those with unfavorable outcomes. The post-stent pressure gradients between the 2 groups were not significantly different (2.8 ± 4.0 mm Hg vs 2.7 ± 2.0 mm Hg, p = 0.934). In a multivariate stepwise logistic regression controlling for age, sex, body mass index, CSF opening pressure, pre-stent pressure gradient, and post-stent pressure gradient, the change in pressure gradient with stent placement was found to be an independent predictor of favorable outcome (p = 0.028). Using a pressure gradient of 21 as a cutoff, 81/86 (94.2%) of patients with a gradient > 21 achieved favorable outcomes, compared with 82/100 (82.0%) of patients with a gradient ≤ 21 (p = 0.022).

CONCLUSIONS

There appears to be a relationship between the pressure gradient of venous sinus stenosis and the success of VSS in IIH. A randomized controlled trial would help elucidate this relationship and potentially guide patient selection.
Botulinum toxin to improve vessel graft patency in cerebral revascularization surgery: report of 3 cases
Authors: Strickland Ben A. , Rennert Robert C. , Bakhsheshian Joshua , Bulic Sebina , Correa Adrian J. , Amar Arun , Carey Joseph , Russin Jonathan J.
Published: March 2018

Surgical revascularization continues to play an important role in the management of complex intracranial aneurysms and ischemic cerebrovascular disease. Graft spasm is a common complication of bypass procedures and can result in ischemia or graft thrombosis. The authors here report on the first clinical use of botulinum toxin to prevent graft spasm following extracranial-intracranial (EC-IC) bypass. This technique was used in 3 EC-IC bypass surgeries, 2 for symptomatic carotid artery occlusions and 1 for a ruptured basilar tip aneurysm. In all 3 cases, the harvested graft was treated ex vivo with botulinum toxin before the anastomosis was performed. Post-bypass vascular imaging demonstrated patency and the absence of spasm in all grafts. Histopathological analyses of treated vessels did not show any immediate endothelial or vessel wall damage. Postoperative angiograms were without graft spasm in all cases. Botulinum toxin may be a reasonable option for preventing graft spasm and maintaining patency in cerebral revascularization procedures.
Invasivität der Douglasie in Südwestdeutschland: Waldinventurdaten erlauben eine Einschätzung
Authors: Bindewald Anja , Michiels Hans-Gerhard
Published: March 2018

Invasiveness of Douglas fir in south-western Germany: an assessment based on forest inventory data

Douglas fir (Pseudotsuga menziesii [Mirb.] Franco) is the most significant tree species of non-native origin in south-western Germany from a commercial point of view. Its importance is expected to increase in the effort to adapt forests to climate change because Douglas fir is considered to be more drought-resistant than, for instance, Norway spruce. Currently, the use of Douglas fir in silviculture and the assessment of its invasiveness are controversially discussed between representatives of nature conservation and forestry. Evidence-based evaluations of the current extent of the establishment and spread of the tree species provide an improved basis for the assessment of invasiveness, as they add objective facts to the discussion and increase the transparency of the process. In this article, we analyze the natural regeneration of Douglas fir in different forest types in the State of Baden-Wurttemberg (south-western Germany) with the help of three systematically collected inventory datasets. The existing natural regeneration serves as a measure for the successful establishment and spread of the species and provides information on its potential invasiveness, i.e. presumable negative impacts on native species and ecosystems. According to the inventory data, the natural regeneration of Douglas fir occurs at a low level (on only 0.3% of the forest surface in Baden-Wurttemberg). However, it naturally regenerates in special protected rare forest habitats, especially on open rocky sites and bolder fields and in sessile oak forest communities on dry sites with acidic soils and mixed broadleaved forests dominated by sycamore. Here, negative impacts might be possible. Thus the species can be considered potentially invasive in these specific conditions. Since Douglas fir natural regeneration was only reported on a proportion of 0.2% of the whole area of monitored protected forest habitats, it should still be possible to successfully eradicate this tree species from these habitats. Data on natural regeneration across a range of different forest types provide an improved basis for the assessment of invasiveness, and thus for identification of appropriate management approaches, such as designating buffer zones around valuable protected habitats.
[18F]-Flutemetamol Uptake in Cortex and White Matter: Comparison with Cerebrospinal Fluid Biomarkers and [18F]-Fludeoxyglucose
Authors: Kalheim Lisa Flem , Fladby Tormod , Coello Christopher , Bjørnerud Atle , Selnes Per
Published: March 2018

Flutemetamol (18F-Flut) is an [18F]-labelled amyloid PET tracer with increasing availability. The main objectives of this study were to investigate 1) cerebrospinal fluid (CSF) Aβ 1-42 (Aβ42) concentrations associated with regional 18F-Flut uptake, 2) associations between cortical 18F-Flut and [18F]-fludeoxyglucose (18F-FDG)-PET, and 3) the potential use of 18F-Flut in WM pathology. Cognitively impaired, nondemented subjects were recruited ( n = 44). CSF was drawn, and 18F-Flut-PET, 18F-FDG-PET, and MRI performed. Our main findings were: 1) Different Alzheimer’s disease predilection areas showed increased 18F-Flut retention at different CSF Aβ42 concentrations (posterior regions were involved at higher concentrations). 2) There were strong negative correlations between regional cortical 18F-Flut and 18F-FDG uptake. 3) Increased 18F-Flut uptake were observed in multiple subcortical regions in amyloid positive subjects, including investigated reference regions. However, WM hyperintensity 18F-Flut standardized uptake value ratios (SUVr) were not significantly different, thus we cannot definitely conclude that the higher uptake in 18F-Flut(+) is due to amyloid deposition. In conclusion, our findings support clinical use of CSF Aβ42, putatively relate decreasing CSF Aβ42 concentrations to a sequence of regional amyloid deposition, and associate amyloid pathology to cortical hypometabolism. However, we cannot conclude that 18F-Flut-PET is a suitable marker for WM pathology due to high aberrant WM uptake.
Induction of Amyloid-β42 Production by Fipronil and Other Pyrazole Insecticides
Authors: Cam Morgane , Durieu Emilie , Bodin Marion , Manousopoulou Antigoni , Koslowski Svenja , Vasylieva Natalia , Barnych Bogdan , Hammock Bruce D. , Bohl Bettina , Koch Philipp , Omori Chiori , Yamamoto Kazuo , Hata Saori , Suzuki Toshiharu , Karg Frank , Gizzi Patrick , Erakovic Haber Vesna , Bencetic Mihaljevic Vlatka , Tavcar Branka , Portelius Erik , Pannee Josef , Blennow Kaj , Zetterberg Henrik , Garbis Spiros D. , Auvray Pierrick , Gerber Hermeto , Fraering Jeremy , Fraering Patrick C. , Meijer Laurent
Published: March 2018

Generation of amyloid-β peptides (Aβs) by proteolytic cleavage of the amyloid-β protein precursor (AβPP), especially increased production of Aβ42/Aβ43 over Aβ40, and their aggregation as oligomers and plaques, represent a characteristic feature of Alzheimer’s disease (AD). In familial AD (FAD), altered Aβ production originates from specific mutations of AβPP or presenilins 1/2 (PS1/PS2), the catalytic subunits of γ-secretase. In sporadic AD, the origin of altered production of Aβs remains unknown. We hypothesize that the ‘human chemical exposome’ contains products able to favor the production of Aβ42/Aβ43 over Aβ40 and shorter Aβs. To detect such products, we screened a library of 3500 + compounds in a cell-based assay for enhanced Aβ42/Aβ43 production. Nine pyrazole insecticides were found to induce a β- and γ-secretase-dependent, 3-10-fold increase in the production of extracellular Aβ42 in various cell lines and neurons differentiated from induced pluripotent stem cells derived from healthy and FAD patients. Immunoprecipitation/mass spectrometry analyses showed increased production of Aβs cleaved at positions 42/43, and reduced production of peptides cleaved at positions 38 and shorter. Strongly supporting a direct effect on γ-secretase activity, pyrazoles shifted the cleavage pattern of another γ-secretase substrate, alcadeinα, and shifted the cleavage of AβPP by highly purified γ-secretase toward Aβ42/Aβ43. Focusing on fipronil, we showed that some of its metabolites, in particular the persistent fipronil sulfone, also favor the production of Aβ42/Aβ43 in both cell-based and cell-free systems. Fipronil administered orally to mice and rats is known to be metabolized rapidly, mostly to fipronil sulfone, which stably accumulates in adipose tissue and brain. In conclusion, several widely used pyrazole insecticides enhance the production of toxic, aggregation prone Aβ42/Aβ43 peptides, suggesting the possible existence of environmental “Alzheimerogens” which may contribute to the initiation and propagation of the amyloidogenic process in sporadic AD.
Innovative Biomarkers for Alzheimer’s Disease: Focus on the Hidden Disease Biomarkers
Authors: Ghidoni Roberta , Squitti Rosanna , Siotto Mariacristina , Benussi Luisa
Published: March 2018

The criteria for the clinical diagnosis of AD include the analysis of biomarkers of the underlying brain disease pathology; a set of cerebrospinal fluid (CSF) tests, amyloid-β1-42 (Aβ42), total-tau (t-tau), and phosphorylated tau (p-tau), are available and their performance in a clinical setting has been assessed in several studies. Thus, in dementia research, great advances have been made in the discovery of putative biomarkers; however, disappointingly, few of them have been translated into clinically applicable assays. To find biomarkers able to reliably detect AD pathology already at prodromal stages and in blood is even more important. Recent technical breakthroughs have provided ultrasensitive methods that allow the detection of brain-specific proteins in blood. In the present review, we will focus on the usefulness of ultrasensitive technologies for biomarker discovery and trace elements detection; moreover, we will review studies on circulating nano-compartments, a promising novel source of material for molecular diagnostics.
Crosstalk between Peripheral Small Vessel Properties and Anxious-like Profiles: Sex, Genotype, and Interaction Effects in Mice with Normal Aging and 3×Tg-AD mice at Advanced Stages of Disease
Authors: Jiménez-Altayó Francesc , Sánchez-Ventura Judith , Vila Elisabet , Giménez-Llort Lydia
Published: March 2018

Cardiovascular disease resulting from oxidative stress and inflammation can exacerbate Alzheimer’s disease. This brief report provides the first evidence of compromised small peripheral mesenteric resistance artery (MRA) properties in 15-month-old 3xTg-AD mice. Females showed worse physiologically relevant MRA structural (increased passive external and internal diameters, cross sectional area) and functional (increased active internal diameters) alterations suggesting sex-dependent dysfunctions. At both physiological and high intraluminal pressures, vascular alterations correlated with the anxious-like behavioral profile, in a sex-dependent manner. Finally, the results unveil a crosstalk between peripheral small vessel properties and behavior in both 3xTg-AD mice and age-matched counterparts with normal aging.
Electromechanical coupled chaotic vibration for electromagnetic railgun
Authors: Xu Lizhong , Zheng Fengjie
Published: March 2018

The chaotic vibration has more important effect on the dynamic performance of the railgun system. It will cause violent vibrations and noise of the mechanical system and also cause large current oscillation in the electric system for the railgun. In this paper, the nonlinear electromechanical coupled dynamics equations for the railgun system are proposed. Using the equations, the nonlinear dynamic performance of the railgun system is investigated. Results show that under some conditions, quasi-periodic vibration and chaotic vibration could occur in the railgun system. The rail current, the distance between two rails, the rail thickness and rail width have effects on the nonlinear vibration of the railgun system. To obtain good dynamic performance of the railgun system, these parameters should be chosen properly. These results are useful in maximizing the power density of the railgun and ensuring launch accuracy.
The Energy Costs of Prematurity and the Neonatal Intensive Care Unit (NICU) Experience
Authors: Tan John , Boskovic Danilo , Angeles Danilyn
Published: March 2018

Premature neonates are in an energy deficient state due to (1) oxygen desaturation and hypoxia events, (2) painful and stressful stimuli, (3) illness, and (4) neurodevelopmental energy requirements. Failure to correct energy deficiency in premature infants may lead to adverse effects such as neurodevelopmental delay and negative long-term metabolic and cardiovascular outcomes. The effects of energy dysregulation and the challenges that clinicians in the Neonatal Intensive Care Unit (NICU) face in meeting the premature infant’s metabolic demands are discussed. Specifically, the focus is on the effects of pain and stress on energy homeostasis. Energy deficiency is a complex problem and requires a multi-faceted solution to promote optimum development of premature infants.
Synthetic Lignan Secoisolariciresinol Diglucoside (LGM2605) Reduces Asbestos-Induced Cytotoxicity in an Nrf2-Dependent and -Independent Manner
Authors: Pietrofesa Ralph , Chatterjee Shampa , Park Kyewon , Arguiri Evguenia , Albelda Steven , Christofidou-Solomidou Melpo
Published: March 2018

Asbestos exposure triggers inflammatory processes associated with oxidative stress and tissue damage linked to malignancy. LGM2605 is the synthetic lignan secoisolariciresinol diglucoside (SDG) with free radical scavenging, antioxidant, and anti-inflammatory properties in diverse inflammatory cell and mouse models, including exposure to asbestos fibers. Nuclear factor-E2 related factor 2 (Nrf2) activation and boosting of endogenous tissue defenses were associated with the protective action of LGM2605 from asbestos-induced cellular damage. To elucidate the role of Nrf2 induction by LGM2605 in protection from asbestos-induced cellular damage, we evaluated LGM2605 in asbestos-exposed macrophages from wild-type (WT) and Nrf2 disrupted (Nrf2−/−) mice. Cells were pretreated with LGM2605 (50 µM and 100 µM) and exposed to asbestos fibers (20 µg/cm2) and evaluated 8 h and 24 h later for inflammasome activation, secreted cytokine levels (interleukin-1β (IL-1β), interleukin-18 (IL-18), interleukin-6 (IL-6), and tumor necrosis factor alpha (TNFα)), cytotoxicity and cell death, nitrosative stress, and Nrf2-regulated enzyme levels. Asbestos exposure induced robust oxidative and nitrosative stress, cell death and cytotoxicity, which were equally mitigated by LGM2605. Inflammasome activation was significantly attenuated in Nrf2−/− macrophages compared to WT, and the protective action of LGM2605 was seen only in WT cells. In conclusion, in a cell model of asbestos-induced toxicity, LGM2605 acts via protective mechanisms that may not involve Nrf2 activation.
Orbital Angular Momentum Generation and Detection by Geometric-Phase Based Metasurfaces
Authors: Chen Menglin , Jiang Li , Sha Wei
Published: March 2018

We present a comprehensive review on the geometric-phase based metasurfaces for orbital angular momentum (OAM) generation and detection. These metasurfaces manipulate the electromagnetic (EM) wave by introducing abrupt phase change, which is strongly dependent on the polarization state of incident EM wave and can be interpreted by geometric phase. Hence, the conventional bulk devices that based on the accumulated phase change along the optical path can be avoided.
Preventive Effects of Lactobacillus Plantarum YS4 on Constipation Induced by Activated Carbon in Mice
Authors: Qian Yu , Song Jia-Le , Yi Ruokun , Li Guijie , Sun Peng , Zhao Xin , Huo Guicheng
Published: March 2018

This study was designed to analyze the effects of Lactobacillus plantarum YS4 (LP-YS4) on activated carbon-induced constipation in ICR (Institute of Cancer Research) mice. The mice were fed on YS4 and LB (Lactobacillus bulgaricus), followed by inducing constipation. The results of the experiment suggested that anti-gastric acid and bile salt activities of LP-YS4 were more effective than LB. It was conclusive that LP-YS4 could inhibit the weight loss induced by constipation and had an effect on fecal weight, particle number and further decrease in water content initiated by constipation. At the same time, LP-YS4 could increase gastrointestinal (GI) transit rate and limit the time of the first black stool defecation. It could also raise the motilin (MTL), endothelin (ET), acetylcholinesterase (AChE), substance P (SP), and vasoactive intestinal peptide (VIP) serum levels and reduce the somatostatin (SS) level in constipated mice as compared to the mice in control group. LP-YS4 could reduce myeloperoxidase (MPO), nitric oxide (NO), and malondialdehyde (MDA) levels in small intestinal tissue of mice and raise glutathione (GSH) levels as compared to the control group mice. By H&E (hematoxylin-eosin) assay, we determined that LP-YS4 could reduce the small intestinal tissue injury by activated carbon. Real-Time Quantitative Polymerase Chain Reaction (RT-qPCR) experiment data demonstrated that LP-YS4 has the capability to increase c-Kit, stem cell factor (SCF), glial cellline-derived neurotrophic factor (GDNF) mRNA (messenger RNA) expressions and decrease transient receptor potential vanilloid 1 (TRPV1), nitric oxide synthase (NOS) expressions in small intestine tissue of constipated mice. High concentration of LP-YS4 exhibited much better effects than that of LB. From these results, LP-YS4 could be considered as an effective substance that actively inhibits constipation.
Influence of Size Reduction of Fly Ash Particles by Grinding on the Chemical Properties of Geopolymers
Authors: Rosas-Casarez Carlos Antonio , Arredondo-Rea Susana Paola , Cruz-Enríquez Adriana , Corral-Higuera Ramón , Pellegrini-Cervantes Manuel de Jesús , Gómez-Soberón José Manuel , Medina-Serna Teresita de Jesús
Published: March 2018

Chemical properties of geopolymers were evaluated from the reduction of fly ash particle size by grinding. X-ray diffraction determined that at early curing ages new crystalline phases appear in the matrix of the geopolymer and they remain for 28 days, with increases in intensities up to 60%. In Fourier transform infrared spectroscopy, displacements were identified in the main band of the geopolymers at higher wavenumbers, attributed to the greater rigidity in the structures of the aluminosilicate gel due to the increase of the reaction products in the geopolymers obtained through fly ashsubjected to previous grinding, which is observable in the geopolymers matrix. Results indicate that the reduction of fly ash particle size by grinding has an influence on the chemical properties of geopolymers.
Transpacific Cyberpunk: Transgeneric Interactions between Prose, Cinema, and Manga
Authors: Tatsumi Takayuki
Published: March 2018

This paper attempts to meditate upon the transpacific imagination of cyberpunk by reconstructing its literary and cultural heritage. Since the publication of William Gibson’s multiple award winning first novel, Neuromancer (1984), the concept of cyberpunk has been globally popularized and disseminated not only in the field of literature but also in culture. However, we should not forget that cyberpunk is derived not only from the cutting edge of technology but also from “Lo Tek” sensibility cultivated in the Gibsonian picturesque ruins or dark cities such as a major extraterritorial zone in Hong Kong “Kowloon Walled City” nicknamed as “a den of iniquity”, “The Casba of the East”, and “a hotbed of crime”, which was destroyed in 1993, but whose images captured by Ryuji Miyamoto inspired Gibson to come up with the spectacle of the destroyed San Francisco Bay Bridge to be stormed by ex-hippies and former homeless. From this perspective, this chapter focuses on the works ranging from Katsuhiro Otomo’s directed anime Akira (1988), Gibson’s Bridge Trilogy (Virtual Light (1993), Idoru (1996), and All Tomorrow’s Parties (1998)) in the 1990s through Project Itoh’s post-cyberpunk masterpiece Genocidal Organ (2007).
Revision of the Kosiński’s Theory of Ordered Fuzzy Numbers
Authors: Piasecki Krzysztof
Published: March 2018

Ordered fuzzy numbers are defined by Kosiński. In this way, he was going to supplement a fuzzy number by orientation. A significant drawback of Kosiński’s theory is that there exist such ordered fuzzy numbers which, in fact, are not fuzzy numbers. For this reason, a fully formalized correct definition of ordered fuzzy numbers is proposed here. Also, the arithmetic proposed by Kosiński has a significant disadvantage. The space of ordered fuzzy numbers is not closed under Kosiński’s addition. On the other hand, many mathematical applications require the considered space be closed under used arithmetic operations. Therefore, the Kosinski’s theory is modified in this way that the space of ordered fuzzy numbers is closed under revised arithmetic operations. In addition, it is shown that the multiple revised sum of finite sequence of ordered fuzzy numbers depends on its summands ordering.
Energy and Economic Performance of Solar Cooling Systems in the Hot-Summer and Cold-Winter Zone
Authors: Huang Li , Zheng Rongyue
Published: March 2018

Building energy consumption has distinctly increased in the hot-summer and cold-winter zone in China. Solar cooling technology has been developed to reduce the increasing electricity consumption for air conditioning and to shift the peak load during hot summer days. This paper presents a performance simulation and economic analysis for both photovoltaic (PV) and thermal solar cooling systems compared to a reference system, which is composed of two electric heat pumps. The results show that 30.7% and 30.2% of primary energy can be saved by using the PV and the thermal system, respectively. The payback time is 6–7 years for the PV system, but more than 20 years for the thermal system based on current conditions in China. Therefore, the PV system is more suitable for practical application in the hot-summer and cold-winter zone. The thermal system could be an alternative when middle- and high-temperature solar thermal collector technology has been further developed, as well as following mass production of small- and middle-sized chillers.
Designing Multifunctionality into Single Phase and Multiphase Metal-Oxide-Selective Propylene Ammoxidation Catalysts
Authors: Brazdil James
Published: March 2018

Multifunctionality is the hallmark of most modern commercial heterogeneous catalyst systems in use today, including those used for the selective ammoxidation of propylene to acrylonitrile. It is the quintessential principle underlying commercial catalyst design efforts since petrochemical process development is invariably driven by the need to reduce manufacturing costs. This is in large part achieved through new and improved catalysts that increase selectivity and productivity. In addition, the future feedstocks for chemical processes will be invariably more refractory than those currently in use (e.g., replacing alkenes with alkanes or using CO2), thus requiring a disparate combination of chemical functions in order to effect multiple chemical transformations with the fewest separate process steps. This review summarizes the key chemical phenomena behind achieving the successful integration of multiple functions into a mixed-metal-oxide-selective ammoxidation catalyst. An experiential and functional catalyst design model is presented that consists of one or both of the following components: (1) a mixed-metal-oxide–solid solution where the individual metal components serve separate and necessary functions in the reaction mechanism through their atomic level interaction in the context of a single crystallographic structure; (2) the required elemental components and their catalytic function existing in separate phases, where these phases are able to interact for the purposes of electron and lattice oxygen transfer through the formation of a structurally coherent interface (i.e., epitaxy) between the separate crystal structures. Examples are provided from the literature and explained in the context of this catalyst design model. The extension of the model concepts to the design of heterogeneous catalysts in general is also discussed.
Detection of AFB1 via TiO2 Nanotubes/Au Nanoparticles/Enzyme Photoelectrochemical Biosensor
Authors: Yuan Qiong , He Chuxian , Mo Rijian , He Lei , Zhou Chunxia , Hong Pengzhi , Sun Shengli , Li Chengyong
Published: March 2018

TiO2 nanotubes/Au nanoparticles/enzyme photoelectrochemical biosensor is developed by the chemical bonding of acetylcholinesterase with Au nanoparticles-modified TiO2 photoactive electrode, based on the inhibitory effect of aflatoxin B1 on acetylcholinesterase activity. In this method, AuNPs were deposited on the surface of the electrode by potentiostatic deposition and the acetylcholinesterase was chemically crosslinked to the surface for determination of aflatoxin B1. Enzymatic hydrolysate is generated to capture the photogenerated holes of UV-sensitized TiO2 nanotube arrays, causing magnification of the photoelectrochemical signal. The photoelectrochemical biosensor morphological and structural details were evaluated, applying different techniques, such as X-ray Diffraction (XRD) and Scanning Electron Microscopy (SEM). Aflatoxin B1 competitively inhibits acetylcholinesterase, leading to a decrease in photocurrent that should have been increased. The detection performance of biosensors for different concentrations of AFB1 is discussed. The linear response range of the biosensor is from 1–6 nM with detection limitation of 0.33 nM, the linear equation is I (μA) = −0.13C (nM) + 9.98 (μA), with a correlation coefficient of 0.988. This new biosensor could be used to detect Aflatoxin B1 in foods.
Enhanced Tribological Properties of Polymer Composite Coating Containing Graphene at Room and Elevated Temperatures
Authors: Zhang Yanchao , Zhang Dongya , Wei Xian , Zhong Shanjun , Wang Jianlei
Published: March 2018

To improve the tribology properties of the polymer coating under elevated temperature, the epoxy coating was reinforced with nano graphene. The micro-hardness, heat conductivity, and thermo-gravimetric properties of the coating were enhanced as filled graphene. The friction and wear properties of the polymer coating were studied using a pin-on-disc tribo-meter under room and elevated temperatures. The results showed that under room temperature, the friction coefficient and the wear rate of the coating adding 4.0 wt % graphene was 80% and 76% lower than that of the neat epoxy coating, respectively. As the test temperature increased, the friction coefficient of the graphene/polymer coatings decreased at first and then slightly increased. The friction coefficient was at its lowest value under 150 °C and then increased as the temperature rose to 200 °C. By adding 4.0 wt % graphene, the friction coefficient and wear rate of the polymer coating were further reduced, especially at elevated temperatures.
Can Ternary Computing Improve Information Assurance?
Authors: Cambou Bertrand , Flikkema Paul , Palmer James , Telesca Donald , Philabaum Christopher
Published: March 2018

Modern computer microarchitectures build on well-established foundations that have encouraged a pattern of computational homogeneity that many cyberattacks depend on. We suggest that balanced ternary logic can be valuable to Internet of Things (IoT) security, authentication of connected vehicles, as well as hardware and software assurance, and have developed a ternary encryption scheme between a computer and smartcard based on public key exchange through non-secure communication channels to demonstrate the value of balanced ternary systems. The concurrent generation of private keys by the computer and the smartcard uses ternary schemes and cryptographic primitives such as ternary physical unclonable functions. While general purpose ternary computers have not succeeded in general use, heterogeneous computing systems with small ternary computing units dedicated to cryptographic functions have the potential to improve information assurance, and may also be designed to execute binary legacy codes.
Gudder’s Theorem and the Born Rule
Authors: De Zela Francisco
Published: March 2018

We derive the Born probability rule from Gudder’s theorem—a theorem that addresses orthogonally-additive functions. These functions are shown to be tightly connected to the functions that enter the definition of a signed measure. By imposing some additional requirements besides orthogonal additivity, the addressed functions are proved to be linear, so they can be given in terms of an inner product. By further restricting them to act on projectors, Gudder’s functions are proved to act as probability measures obeying Born’s rule. The procedure does not invoke any property that fully lies within the quantum framework, so Born’s rule is shown to apply within both the classical and the quantum domains.
IBVis: Interactive Visual Analytics for Information Bottleneck Based Trajectory Clustering
Authors: Guo Yuejun , Xu Qing , Sbert Mateu
Published: March 2018

Analyzing trajectory data plays an important role in practical applications, and clustering is one of the most widely used techniques for this task. The clustering approach based on information bottleneck (IB) principle has shown its effectiveness for trajectory data, in which a predefined number of the clusters and an explicit distance measure between trajectories are not required. However, presenting directly the final results of IB clustering gives no clear idea of both trajectory data and clustering process. Visual analytics actually provides a powerful methodology to address this issue. In this paper, we present an interactive visual analytics prototype called IBVis to supply an expressive investigation of IB-based trajectory clustering. IBVis provides various views to graphically present the key components of IB and the current clustering results. Rich user interactions drive different views work together, so as to monitor and steer the clustering procedure and to refine the results. In this way, insights on how to make better use of IB for different featured trajectory data can be gained for users, leading to better analyzing and understanding trajectory data. The applicability of IBVis has been evidenced in usage scenarios. In addition, the conducted user study shows IBVis is well designed and helpful for users.
Revisiting Degrees of Freedom of Full-Duplex Systems with Opportunistic Transmission: An Improved User Scaling Law
Authors: Kim Haksoo , Kim Juyeop , Choi Sang , Shin Won-Yong
Published: March 2018

It was recently studied how to achieve the optimal degrees of freedom (DoF) in a multi-antenna full-duplex system with partial channel state information (CSI). In this paper, we revisit the DoF of a multiple-antenna full-duplex system using opportunistic transmission under the partial CSI, in which a full-duplex base station having M transmit antennas and M receive antennas supports a set of half-duplex mobile stations (MSs) having a single antenna each. Assuming no self-interference, we present a new hybrid opportunistic scheduling method that achieves the optimal sum DoF under an improved user scaling law. Unlike the state-of-the-art scheduling method, our method is designed in the sense that the scheduling role between downlink MSs and uplink MSs is well-balanced. It is shown that the optimal sum DoF of 2 M is asymptotically achievable provided that the number of MSs scales faster than SNR M , where SNR denotes the signal-to-noise ratio. This result reveals that, in our full-duplex system, better performance on the user scaling law can be obtained without extra CSI, compared to the prior work that showed the required user scaling condition (i.e., the minimum number of MSs for guaranteeing the optimal DoF) of SNR 2 M − 1 . Moreover, the average interference decaying rate is analyzed. Numerical evaluation is performed to not only validate our analysis but also show superiority of the proposed method over the state-of-the-art method.
Pathways to the Professoriate: The Experiences of First-Generation Latino Undergraduate Students at Hispanic Serving Institutions Applying to Doctoral Programs
Authors: Martinez Andrew
Published: March 2018

Despite representing the largest ethnic minority group in the United States, Latinos remain underrepresented in the professoriate. Although Latinos are increasingly attending college, fewer graduate and even fewer continue to pursue graduate school. Prior research has explained the challenges that first-generation college students encounter in post-secondary contexts. Given that Latino college students are likely to be first-generation, understanding the experiences of first-generation Latino undergraduate students who aspire to be professors and are applying to graduate school can help illuminate what factors help support this underrepresented group in pursuing a career in the academy. Using qualitative approaches, this study describes the experiences of 15 first-generation undergraduate Latino students in a grant funded academic program that provides them with a plethora of resources to help prepare them for graduate school applications. The findings suggest how early exposure to information about applying to graduate school, access to role models, familial support and understanding of an academic career and having a community of peers with similar ambitions can help cultivate an environment where first-generation, Latino students remain inspired and committed to pursuing graduate school in efforts to become a professor.
Line-to-Line Fault Analysis and Location in a VSC-Based Low-Voltage DC Distribution Network
Authors: Xue Shi-Min , Liu Chong
Published: March 2018

A DC cable short-circuit fault is the most severe fault type that occurs in DC distribution networks, having a negative impact on transmission equipment and the stability of system operation. When a short-circuit fault occurs in a DC distribution network based on a voltage source converter (VSC), an in-depth analysis and characterization of the fault is of great significance to establish relay protection, devise fault current limiters and realize fault location. However, research on short-circuit faults in VSC-based low-voltage DC (LVDC) systems, which are greatly different from high-voltage DC (HVDC) systems, is currently stagnant. The existing research in this area is not conclusive, with further study required to explain findings in HVDC systems that do not fit with simulated results or lack thorough theoretical analyses. In this paper, faults are divided into transient- and steady-state faults, and detailed formulas are provided. A more thorough and practical theoretical analysis with fewer errors can be used to develop protection schemes and short-circuit fault locations based on transient- and steady-state analytic formulas. Compared to the classical methods, the fault analyses in this paper provide more accurate computed results of fault current. Thus, the fault location method can rapidly evaluate the distance between the fault and converter. The analyses of error increase and an improved handshaking method coordinating with the proposed location method are presented.
Three-Phase Short-Circuit Current Calculation of Power Systems with High Penetration of VSC-Based Renewable Energy
Authors: Zhou Niancheng , Wu Jiafang , Wang Qianggang
Published: March 2018

Short-circuit current level of power grid will be increased with high penetration of VSC-based renewable energy, and a strong coupling between transient fault process and control strategy will change the fault features. The full current expression of VSC-based renewable energy was obtained according to transient characteristics of short-circuit current. Furtherly, by analyzing the closed-loop transfer function model of controller and current source characteristics presented in steady state during a fault, equivalent circuits of VSC-based renewable energy of fault transient state and steady state were proposed, respectively. Then the correctness of the theory was verified by experimental tests. In addition, for power grid with VSC-based renewable energy, superposition theorem was used to calculate AC component and DC component of short-circuit current, respectively, then the peak value of short-circuit current was evaluated effectively. The calculated results could be used for grid planning and design, short-circuit current management as well as adjustment of relay protection. Based on comparing calculation and simulation results of 6-node 500 kV Huainan power grid and 35-node 220 kV Huaisu power grid, the effectiveness of the proposed method was verified.
Impact of Coil Misalignment in Data Transmission over the Inductive Link of an EV Wireless Charger
Authors: Triviño-Cabrera Alicia , Lin Zhengyu , Aguado José
Published: March 2018

The penetration rate of electric vehicles (EVs) will experience a relative increment in the future, so easy to use ways to recharge will be demanded. In this sense, wireless charging represents a safe charging method that minimises user intervention. In a similar way to conductive charge, wireless charging requires some information exchange between the charger primary side and secondary side (battery) for safety and operational reasons. Thus, wireless chargers depend on a communication system for their controlled and correct operation. This paper analysed the communication performance of a wireless EV charger in which the communiction device is part of the wireless power transfer system. Particularly, this work studies how the communication system reacts to power coil displacements, which commonly occur in their conventional performance. The results show that the compensation topology selected to ensure the resonant operation clearly impacts on the communication performance. In particular, the theoretical model and the simulation results demonstrate that the asymmetrical compensation topologies are more stable in terms of the wireless communication channel capacity.
Modified Differential Evolution Algorithm: A Novel Approach to Optimize the Operation of Hydrothermal Power Systems while Considering the Different Constraints and Valve Point Loading Effects
Authors: Nguyen Thang Trung , Vu Quynh Nguyen , Duong Minh Quan , Van Dai Le
Published: March 2018

This paper proposes an efficient and new modified differential evolution algorithm (ENMDE) for solving two short-term hydrothermal scheduling (STHTS) problems. The first is to take the available water constraint into account, and the second is to consider the reservoir volume constraints. The proposed method in this paper is a new, improved version of the conventional differential evolution (CDE) method to enhance solution quality and shorten the maximum number of iterations based on two new modifications. The first focuses on a self-tuned mutation operation to open the local search zone based on the evaluation of the quality of the solution, while the second focuses on a leading group selection technique to keep a set of dominant solutions. The contribution of each modification to the superiority of the proposed method over CDE is also investigated by implementing CDE with the self-tuned mutation (STMDE), CDE with the leading group selection technique (LGSDE), and CDE with the two modifications. In addition, particle swarm optimization (PSO), the bat algorithm (BA), and the flower pollination algorithm (FPA) methods are also implemented through four study cases for the first problem, and two study cases for the second problem. Through extensive numerical study cases, the effectiveness of the proposed approach is confirmed.
Mechanical Frequency Response Analysis of Lithium-Ion Batteries to Disclose Operational Parameters
Authors: Popp Hartmut , Glanz Gregor , Alten Karoline , Gocheva Irina , Berghold Wernfried , Bergmann Alexander
Published: March 2018

During the charge and discharge process, lithium-ion batteries change their mechanical properties due to internal structural changes caused by intercalation and de-intercalation of the ions in the anode and cathode. Furthermore, the behavior changes over the lifetime of the battery due to several degradation mechanisms. The mechanical properties of the cell hold valuable information for monitoring these changes and additionally provide data for mechanical construction and further optimization of battery systems. Hence, in this manuscript, the mechanical frequency response function is investigated as a non-destructive method to determine parameters such as stiffness and damping of pouch cells and their correlation with the state of charge (SOC), the state of health (SOH), and the temperature of the cell. Using a mechanical shaker and an impedance head, it is shown that low amplitude forces of only a few Newton and a low frequency region of several hundred Hertz already suffice to show differences in the state of charge and state of health as well as in mechanical properties and the dependencies on temperature. Also the limitations of the method are shown, as the frequency response is not distinct for each parameter and thus, at the moment, does not allow absolute determination of a single value without prior system knowledge.
Line-Interactive Transformerless Uninterruptible Power Supply (UPS) with a Fuel Cell as the Primary Source
Authors: Iftikhar Muhammad , Aamir Muhammad , Waqar Asad , Naila  , Muslim Fahad Bin , Alam Imtiaz
Published: March 2018

This paper presents line-interactive transformerless Uninterruptible Power Supply (UPS) with a fuel cell as the prime energy source. The proposed UPS consists of three major parts (i.e., an output inverter, a unidirectional DC–DC converter, and a battery charger/discharger). Non-isolated topologies of both the unidirectional converter and battery charger/discharger ensure transformerless operation of the UPS system. A new topology of high gain converter is employed for boosting the low voltage of the fuel cell to a higher DC link voltage, with minimum semiconductor count, and high efficiency. A high-gain battery charger/discharger realizes the bidirectional operation between the DC link and the battery bank. Besides, it regulates the DC link voltage during the cold start of fuel cells and keeps the battery bank voltage to only 24 V. A new inverter control scheme is introduced that regulates the output voltage and minimizes the total harmonic distortion for non-linear loading condition. The proposed control scheme integrates proportional-resonant control with slide mode control, which improves the controller’s performance in transient conditions. The proposed UPS system is validated by developing a 1-kVA experimental prototype.
Entropy Generation and Exergy Destruction in Flow of Multiphase Dispersions of Droplets and Particles in a Polymeric Liquid
Authors: Pal Rajinder
Published: March 2018

The theoretical background for entropy generation and exergy destruction in the flow of fluids is reviewed briefly. New experimental results are presented on the quantification of exergy destruction rates in flows of emulsions (oil droplets dispersed in a polymeric liquid), suspensions (solid particles dispersed in a polymeric liquid), and blends of emulsions and suspensions (dispersions of oil droplets and solid particles in a polymeric liquid). A new model is proposed to estimate the exergy destruction rate, and hence power loss, in the flow of multi-phase dispersions of oil droplets, solid particles, and polymeric matrix.