bluuebunny/crossref_metadata_2025 huggingface dataset:
Amyloid Beta Peptide-Mediated Alterations in Mitochondrial Dynamics
and its Implications for Alzheimer’s Disease
Authors: Monsalvo-Maraver Luis Ángel , Maya-López Marisol , Rangel-López Edgar , Túnez Isaac , Tinkov Alexey A. , Skalny Anatoly , Ferrer Beatriz , Aschner Michael , Santamaría Abel
Published: June 2022

Alzheimer’s disease (AD) is considered the most frequent neurodegenerative disorder
worldwide, compromising cognitive function in patients, with an average incidence of 1-3% in the
open population. Protein aggregation into amyloidogenic plaques and neurofibrillary tangles, as well
as neurodegeneration in the hippocampal and cortical areas, represent the neuropathological hallmarks
of this disorder. Mechanisms involved in neurodegeneration include protein misfolding, augmented
apoptosis, disrupted molecular signaling pathways and axonal transport, oxidative stress, inflammation,
and mitochondrial dysfunction, among others. It is precisely through a disrupted energy metabolism
that neural cells trigger toxic mechanisms leading to cell death. In this regard, the study of mitochondrial
dynamics constitutes a relevant topic to decipher the role of mitochondrial dysfunction in
neurological disorders, especially when considering that amyloid-beta peptides can target mitochondria.
Specifically, the amyloid beta (Aβ) peptide, known to accumulate in the brain of AD patients, has
been shown to disrupt overall mitochondrial metabolism by impairing energy production, mitochondrial
redox activity, and calcium homeostasis, thus highlighting its key role in the AD pathogenesis. In
this work, we review and discuss recent evidence supporting the concept that mitochondrial dysfunction
mediated by amyloid peptides contributes to the development of AD.
Multi-temporal Cloud Pixels Reconstruction Method for Optical Remote
Sensing Satellite Images
Authors: Liu Huiqian , Zhong Ruofei , Wang Haiyin , Wu Shiyong , Li Qingyang , Yang Cankun
Published: June 2022

Bachground:

The existence of cloud pixels reduces the practicability of optical satellite remote sensing data.

Existing problems:

Existing cloud reconstruction methods generally cannot solve the following problems:(1)Large-scale thick cloud cannot be well reconstructed. (2)There are high requirements for reconstructed data. (3)Most data used to reconstructed are single temporal images.

Ways:

In order to overcome these problems, a new multi temporal weighted aggregation method is proposed. Specifically, we adopt a multi-temporal iterative aggregation method for cloud pixels to reconstruct and a multi-temporal weighted aggregation method for cloud shadow pixels to reconstruct.

Result:

Finally, the experiment proves that our method can quickly and accurately complete the cloud reconstruction, and under the effective uniform color strategy, a cloud- free image with accurate geometric position and uniform gray scale can be obtained.

Conclusion:

Experiments prove that the pixel reconstruction method proposed in this paper has achieved good cloud and cloud shadow pixel reconstruction effects in different types of ground objects.
Formulation and Development of Nanostructured Lipid Carriers for a
Poorly Water-Soluble Drug: Furosemide
Authors: Jadhav Abhish B. , Savkare Anand D. , Gaikwad Sachin S.
Published: June 2022

Aim:

Formulation, development and evaluation of solid lipid nanoparticles.

Background:

It was found that furosemide (FU) was a very potent drug but it fails to produce bioavailability
due to its BCS class IV, so drug- cyclodextrin (CD)- nanostructured lipid carriers
(NLC) will be an alternative to improve solubility and permeability as a result of this overall bioavaibility
will be improved.

Objective:

To improve the solubility of drug by using complexation of cyclodextrin. Coating with
the lipids (NLC) will improve the permeability of the drug.

Methods:

To generate solid Furosemide–cyclodextrin complexes (FU–CD), two distinct CDs and
three different techniques were used. The co-evaporation (COE) Furosemide-β-cyclodextrinloaded
NLC (FU– β-CD-COE-loaded NLC) was obtained by emulsification ultrasonic dispersion
method. The selected batch was suitably characterized for particle size, polydispersity index, zeta
potential, Entrapment efficiency, Drug release study, and permeability study. The crystallization of
the drug in the furosemide cyclodextrin complex (FU–CD complex) and the co-evaporation Furosemide-
β-cyclodextrin-loaded NLC (FU–β-CD-COE-loaded NLC) was investigated by differential
scanning calorimetry (DSC). The in vitro release study was carried out.

Results:

The FU–β-CD-COE-loaded NLC and FU–HP-β-CD-COE-loaded NLC (Hydroxypropyl)
presented a superior physicochemical property and were selected for further study. The in vitro release
study of the above selected batches exhibited a higher dissolution rate in the pH 5.8 phosphate
buffer than Furosemide suspension and FU–NLC. The permeability studies of abovementioned
batches were compared with FU-Suspension.

Conclusion:

The novel formulation considerably enhanced the solubility and permeability of furosemide
for oral delivery, and was successfully developed.
Role of Ultrasound Imaging in Hepatic Lesions and its Correlation with Fine Needle Aspiration Cytology
Authors: Pabla Navreet Singh , Rastogi Swantantra Kumar , Madhok Rajneesh , Pant Hema
Published: June 2022

Introduction: Ultrasound is cheaper, effective, quick, painless,
non-invasive with no radiation hazard. Guided FNAC of the
liver is a safe, simple, cost-effective and accurate method
for cytological diagnosis of hepatic lesions. To study the role
of sonography findings including color doppler in Hepatic
Lesions and its correlation with Fine Needle Aspiration
Cytology.
Materials and Methods: Patients referred to the department
of Radiodiagnosis for Sonological evaluation were screened for
hepatic SOLs. Patients with liver SOL were included in the study .
Protocols included History, Routine laboratory and conventional
radiological investigations, Ultrasonographic and Colour Doppler
examination for size, margins, and color flow, intrahepatic bile
duct status and lymph nodes followed byUSG guided FNA of
the lesions and cytological co-relation
Results: Out of 54 patients (28 male and 26 females), 37
patients had malignant (metastatic/primary) lesions and 12
had benign lesions. In 5 patients samples were inadequate for
analysis. Maximum no of malignant cases were 15, in the age
group of 41-60 years and benign cases were 5 each, in age less
than 40 years and in age group 41-60 yrs.On ultrasound, 28
patients had single lesions while 26 had multiple lesions. Most
of the patients (30/54) had lesions in right lobe while only 10
patients had lesions in left lobe. In 14 patients, lesions were
present in both lobes.
Conclusion: The sensitivity and specificity of ultrasound
findings with Fine needle aspiration cytology was 78.4% and
91.7% respectively for diagnosis of malignant lesions.
Optimum Treatment of Carcinoma Esophagus in Geriatric Age with Multiple Comorbidities- A Case Report with Review of Literature
Authors: Upadhyay Prachi , Chauhan Arvind Kumar , Kumar Piyush
Published: June 2022

Introduction: Standard management of concurrent chemo
radiotherapy (CCRT) in upper and middle 1/3rd of cancer
esophagus may be challenging to practice in the geriatric
age group with multiple comorbid conditions. The treatment
may lead to life threatening side effects while compromised
treatment may lead to failure of the case. The present case
reports the treatment of cancer esophagus patient in geriatric
age group with multiple comorbidities treated with standard
regimen of concurrent chemoradiation.
Case History: Sixty years old male with several comorbid
conditions presented to our OPD with complaints of difficulty
in swallowing in the past 6 months. Upper gastrointestinal
endoscopy revealed ulcerated mass whose biopsy was
suggestive of moderately differentiated squamous cell
carcinoma. Positron emission tomography- computed
tomography whole body scan revealed localized well-defined
lesion in upper one third of the esophagus.
Echocardiography (2D Echo) showed cardiac comorbidity
for which medications were prescribed and close monitoring
was done by cardiologist. Diabetes was monitored by general
physician and proper diet by nutritionist.
Patient was treated with standard CCRT protocol. There
were no significant toxicities related to radiotherapy and
chemotherapy. After 1 month of treatment upper gastrointestinal
endoscopy revealed normal benign esopheagal mucosa. Follow
up PET CT was done after 3 months which showed significant
decrease with no new lesion. After one year follow up patient
has no complaints of dysphagia.
Conclusion: Geriatric patients of upper or middle 1/3rd
esophagus can be treated with standard chemo radiotherapy
regimes by radiation oncologist in association with team of other
physicians with regular monitoring of the comorbid conditions.
A study on the effect of consumers’ online shopping styles on satisfaction and repurchase intention
Authors:   Department of Industrial Management, Gyeongsang National University, Jinju, South Korea, et al. Khongorzul
Published: June 2022

Distribution companies such as online shopping malls have the same product as their competitors, have limited price policies, and have a competitive advantage over other companies. It is necessary to develop a service that customers prefer at an appropriate cost. The quality of service these companies provide and their service strategy should be accurately measured and checked if valid. This study identifies the effects of online shopping malls on consumer satisfaction and repurchase intention. In addition, it explores him moderating role of the shopping style of the consumers. A total of 149 valid responses out of 200 distributed survey questionnaires from March 15, 2021, to March 30, 2021, were used to test the hypotheses among online shopping users. As for the research analysis, frequency analysis was performed for demographic characteristics, and reliability analysis, correlation analysis, and factor analysis were performed for the validity of the items. In addition, path analysis was performed to verify the hypothesis. The results are as follows. First, the online shopping mall characteristics including product diversity and price significantly affect shopping satisfaction, while the product information does not. Second, shopping satisfaction affects repurchase objectives. Finally, the study identifies the moderating role of the shopping approach in the relationship between online shopping mall attributes and satisfaction.
Restoration characteristics of the internal healing environments: The specialty of visually extended space neighboring multi-story housing
Authors:   Department of Architecture, College of Engineering, University of Mosul, Mosul, Iraq, Abdulrazaq Rawan Hasan , Younis Ghada M. ,   Department of Architecture, College of Engineering, University of Mosul, Mosul, Iraq
Published: June 2022

The concept of restoration is linked to the objectives achieved by the design characteristics of the internal space that support users' physical and mental health in recovery, improvement, vitality in performance, and stimulation of activity. The research addressed the design characteristics that give restoration features to the internal spaces as a design strategy to support the health of the individuals, that by adopting one of those characteristics which are the visually extended views neighboring, which is required for multi-story housing buildings through the views achieved by the permeability of the residential unit with the neighboring nature. The research, in its methodology, relied on getting a theoretical framework for the main items of the characteristics of the restoration spaces through the direct and indirect impact on the physical, mental and psychological health of the residents. The objectives of the research are concerned with discovering the impact of visual extended factors achieved by the external boundaries of the residential unit on its natural surroundings, a selected sample of 10 housing projects in Erbil/Iraq was measured. The research hypothesis was tested using Isovist-graph software for one of the comprehensive visual characteristics of the optical axes (Entropy), which determines the amount of comprehensive information about the internal spaces that can be known from the point of entry. The conclusion is the impact of the visual depth on the formation of axes of the visual extended that is held by a relationship of the external natural boundaries of the residential unit, and therefore the diversity in the visual characteristics of the spaces extending outside, which give the renewal and vitality to the spaces used.
Muzyka – kosmos – miłość
Authors: Lipka Krzysztof
Published: June 2022

Music makes ties with the cosmos; it is an essential and structural bond. However, music is made by man, who pours into it his own emotions. Because of music, man enters into a new relationship with the cosmos. Relation, which is not only exploratory, scientific, intellectual, or superstitious but thanks to music, it is emotional, intimate, and artis- tic. Man always sent music into the cosmos in his phantasies, prayers, and dreams, but in the twenty century, it happened in reality. The man shut a ready musical work into faraway cosmic space. The pioneering role in this matter was given again, although in absentia, to Beethoven. It is one more tie of the last Viennese classic with existence, the total relation, final and entering the cosmos as if to prove to Popper’s claim that culture thrusts into being an element of surprise, without which human existence is impossible.
Role of Social and App-Related Factors in Behavioral Engagement With mHealth for Improved Well-being Among Chronically Ill Patients: Scenario-Based Survey Study
Authors: Van Baelen Freek , De Regge Melissa , Larivière Bart , Verleye Katrien , Schelfout Sam , Eeckloo Kristof
Published: June 2022

Background

The last decade has seen a considerable increase in the number of mobile health (mHealth) apps in everyday life. These mHealth apps have the potential to significantly improve the well-being of chronically ill patients. However, behavioral engagement with mHealth apps remains low.

Objective

The aim of this study was to describe the behavioral engagement of chronically ill patients with mHealth apps by investigating (1) how it is affected by social factors (ie, physician recommendation) and app-related factors (ie, app integration) and (2) how it affects patient well-being. This study also considers the moderating effect of attachment to traditional health care and the mobile app experience among patients.

Methods

We carried out a scenario-based survey study of chronically ill patients (N=521). A Bayesian structural equation modeling with mediation and moderation analysis was conducted in MPlus.

Results

Both physician recommendations for mHealth app use and app integration have positive effects on the behavioral engagement of chronically ill patients with mHealth apps. Higher behavioral engagement positively affects the hedonic well-being (extent of pleasure) and the eudaemonic well-being (extent of self-efficacy) of chronically ill patients. Mobile app experience, however, positively moderates the relationship between app integration and behavioral engagement, whereas patient attachment to traditional care does not moderate the relationship between physician recommendation and behavioral engagement. Taken together, the proportion of variance explained (R²) equals 21% for behavioral engagement and 52.8% and 62.2% for hedonic and eudaemonic well-being, respectively, thereby providing support for the strong influence of app integration and physician recommendation via the mediation of the patients’ behavioral engagement on both patients’ hedonic and eudaemonic well-being.

Conclusions

Physician recommendation and app integration enable behavioral engagement and promote well-being among chronically ill patients. It is thus important to take social and app-related factors into consideration during and after the development of mHealth apps.
Perceptions of Using Instant Messaging Apps for Alcohol Reduction Intervention Among University Student Drinkers: Semistructured Interview Study With Chinese University Students in Hong Kong (Preprint)
Authors: Chau Siu Long , Wong Yiu Cheong , Zeng Ying Pei , Lee Jung Jae , Wang Man Ping
Published: June 2022

BACKGROUND

Mobile instant messaging (IM) apps (eg, WhatsApp and WeChat) have been widely used by the general population and are more interactive than text-based programs (SMS text messaging) to modify unhealthy lifestyles. Little is known about IM app use for health promotion, including alcohol reduction for university students.

OBJECTIVE

This study aims to explore university student drinkers' perceptions of using IM apps for alcohol reduction as they had high alcohol exposure (eg, drinking invitations from peers and alcohol promotion on campus) and the proportion of IM app use in Hong Kong.

METHODS

A qualitative study was conducted with 20 Hong Kong Chinese university students (current drinkers) with Alcohol Use Disorder Identification test scores of ≥8 recruited using purposive sampling. Semistructured individual interviews were conducted from September to October 2019. Interview questions focused on drinking behaviors, quitting history, opinions toward IM app use as an intervention tool, perceived usefulness of IM apps for alcohol reduction, and opinions on the content and design of IM apps for alcohol reduction. Each interview lasted approximately 1 hour. All interviews were audio-taped and transcribed verbatim. Two researchers independently analyzed the transcripts using thematic analysis with an additional investigator to verify the consistency of the coding.

RESULTS

Participants considered IM apps a feasible and acceptable platform for alcohol reduction intervention. They preferred to receive IMs based on personalized problem-solving and drinking consequences with credible sources. Other perceived important components of instant messages included providing psychosocial support in time and setting goals with participants to reduce drinking. They further provided suggestions on the designs of IM interventions, in which they preferred simple and concise messages, chat styles based on participants' preferences (eg, adding personalized emojis and stickers in the chat), and peers as counselors.

CONCLUSIONS

Qualitative interviews with Chinese university student drinkers showed high acceptability, engagement, and perceived utility of IM apps for alcohol reduction intervention. IM intervention can be an alternative for alcohol reduction intervention apart from traditional text-based programs. The study has implications for developing the IM intervention for other unhealthy behaviors and highlights important topics that warrant future research, including substance use and physical inactivity.

CLINICALTRIAL

ClinicalTrials.gov NCT04025151; https://clinicaltrials.gov/ct2/show/NCT04025151?term=NCT04025151
Two Wars in the Order of Time: Cyprus, 1974, Ukraine, 2022
Authors: Saldanha-Álvarez José Maurício
Published: June 2022

Two cases are studied, the first being the invasion of Cyprus by Turkiye in 1974, when the Greek-Cypriot community wanted to integrate the island into mainland Greece, threatening the rise of Turkish Cypriots. The government of Turkiye invaded the island, conquering a portion of the territory for its supporters, believing to resolve the issue culminating in decades of conflict between their communities whose past dreams do not coincide with the present. The second event is Vladimir Putin’s Russian invasion of Ukraine in 2022, motivated by the irreversible process of the dissolution of the former USSR and the attraction of Ukrainians to the western orbit. From a notion of the strangeness of contemporaneity, anchored in a glorious but unattainable past, events that erupt in contemporaneity are simultaneously current and anachronistic Based on a premise of the past and defending ethnic Russians, Putin recovers the fantasy of a Russian empire encompassing tsarist, communist, and orthodox religion from the past. In Cyprus, Greek and Turkish Cypriots dreamed of integration into the respective motherland, but in both cases, contemporary and historic irruption of the past possess the unbeatable force of a cosmic event.
Migración en el sistema Meso-Norteamericano
Authors: Schiavon Jorge A.
Published: June 2022

El objetivo central de este dossier es analizar el fenómeno migratorio en el sistema Meso-Norteamericano de manera integral e interdisciplinar. Este sistema incluye a Canadá, Estados Unidos y México (en América del Norte), Belice, El Salvador, Guatemala y Honduras (en América Central), y Cuba, Haití, Puerto Rico, República Dominicana y Jamaica (en el Caribe). Para ello, se convocó a algunos de los mayores expertos académicos en la región sobre el tema, quienes estudian integralmente la migración en este sistema, con énfasis en México como espacio central donde ocurren los cinco componentes de la migración, a saber, emigración, inmigración, tránsito, retorno y refugio.
Comparison of azithromycin and a combination of trypsin, chymotrypsin and papain proteolytic enzymes for the treatment of bovine cutaneous papillomatosis
Authors: Deveci Mehmet Zeki Yılmaz , Altuğ Muhammed Enes , Alakuş Halil , Ozsoy Şule Yurdagül
Published: June 2022

Although various methods have been used in the treatment of bovine cutaneous papillomatosis (BCP), no definite treatment has yet been established. There are no studies regarding the efficacy of azithromycin (AZ) and of any combination of trypsin, chymotrypsin, and papain proteolytic enzymes (PEC) in the treatment of BCP. The objective of this study was to investigate the efficacy of AZ and PEC in the treatment of BCP. A total of 24 female Holstein cattle of 6-17 months of age with spontaneous BCP were used for this study. In addition to the clinical findings, the diagnosis was confirmed with histopathological examinations. The animals were divided at random into three groups (n = 8). The AZ group received 10 mg/kg/day PO for 10 days. In the PEC group, an injectable suspension of proteolytic enzymes was applied IM at 0.4 mL/10 kg dose, 3 times with 8-10 days interval and the spray was used topically once a day for 10 days. The control group (CO) was not treated. The mean in papilloma warts decreased 92.4 % in the AZ group, 83.38 % in the PEC group, and 59.48 % in the CO. There were statistically significant differences in warts presence decreases between the three groups (P < 0.05). Both AZ and PEC were considered successful for the BCP treatment. However, AZ was found more effective than PEC.
Ruidos articulares en pacientes rehabilitados con prótesis parcial removible
Authors: Huber Laura , López Vallejos María Julia , Rosende Roque Óscar
Published: June 2022

Los ruidos articulares constituyen junto a las restricciones mandibulares, los signos clásicos de los trastornos temporomandibulares (TTM) que pueden ir acompañados por sintomatología dolorosa. Su etiología multifactorial reconoce estrés emocional, traumatismo, dolor profundo, actividad parafuncional y problemas oclusales. El objetivo de este estudio descriptivo transversal fue determinar la frecuencia y tipos de ruidos articulares y su relación con las clases de Kennedy y la presencia o ausencia de sintomatología dolorosa. Se realizó exploración táctil y auscultación de la articulación temporomandibular (ATM) a 50 pacientes concurrentes a la Cátedra Clínica de Prótesis I curso. La incidencia de ruidos articulares fue del 48%: clics simples 48.15%, clics recíprocos 25.9%, pop 18.5%, y crepitaciones 7.4%. La anamnesis mostró presencia de dolor en un 14%. La coincidencia de ambos signos (dolor y ruido) coincidió en un 25%. Se presentó la alta incidencia de clics simples relacionada con la clase II de Kennedy.
Presencia del cuarto molar. Revisión de la literatura
Authors: Vázquez Mosqueyra Víctor Manuel , Espinosa Meléndez María Teresa , Hernández Flores Florentino
Published: June 2022

El cuarto molar, también llamado distomolar, es una variante de número y forma que se presenta como una alteración durante la odontogénesis, pueden ser eumórfico o dismórfico, único o múltiple, erupcionado o retenido, de forma unilateral o bilateral y se puede presentar en ambos maxilares. La etiología es desconocida, pero existen varias teorías que justifican el desarrollo de esta alteración dentaria como la duplicación de la lámina dental, su proliferación horizontal o hiperactividad de ésta; otros factores pueden ser los hereditarios, la división completa del germen dentario o regresión fi logenética. El cuarto molar se encuentra en un espacio muy importante, que al desconocer su existencia o técnica adecuada para su extracción, las posibilidades de tener severas complicaciones trans- y postoperatorias son altas. Se realiza una revisión bibliográfi ca de diferentes artículos y textos en diferentes años para determinar de forma más clara el origen y formación de este diente supernumerario.
Estudio comparativo niveles de ansiedad y disfunción temporomandibular en estudiantes universitarios de Argentina-México
Authors: Mendiburu Zavala Celia Elena Del Perpetuo Socorro , Cárdenas Erosa Rubén , Peñaloza Cuevas Ricardo , Carrillo Mendiburu Edwin , Basulto López Lucero
Published: June 2022

Introducción: La ansiedad es el trastorno más generalizado entre universitarios, pudiendo ser conducente a alguna disfunción física como la DTM, cuyos síntomas son dolor en músculos de cara y cuello, otalgia y cefalea. Objetivo: Comparar la relación entre los niveles de ansiedad y grado de disfunción temporomandibular (DTM) en estudiantes de la Universidad Nacional de Córdoba, Argentina, y de la Universidad Autónoma de Yucatán, México, en el periodo de mayo de 2017 a febrero de 2018. Material y métodos: Muestra de 117 estudiantes universitarios argentinos y 80 mexicanos, quienes firmaron carta de consentimiento informado y voluntario, cédula de investigación para identificar edad, sexo y grado escolar. Asimismo, tres cuestionarios de autoevaluación: 1. índice anamnésico de Fonseca con 10 preguntas, dependiendo de la suma, determina el grado de DTM; 2. dos escalas para medir ansiedad estado y ansiedad rasgo, State-Trait Anxiety Inventory (STAI), con 20 ítems c/u. La suma y una recodificación evalúan el nivel de ansiedad. Se utilizó estadística descriptiva e inferencial. Resultados: Según la nacionalidad de los participantes, no se encontraron diferencias significativas en los niveles de ansiedad a un nivel de 5% de significancia (U = 4,599, p = 0.828). En ambos países hubo menor porcentaje de estudiantes universitarios que no presentaron ansiedad, y el nivel más prevalente en ambos, fue el bajo. No existió diferencias estadísticamente significativas en los grados de DTM (U = 4,325, p = 0.325). Ambas nacionalidades tuvieron mayor prevalencia leve de DTM. Conclusiones: Sólo las mujeres (en ambas universidades) presentan grado severo de DTM y niveles altos de ansiedad
Repercusiones orales en consumidores de metanfetaminas y presentación de un caso
Authors: Salvador Valadez Gerardo , González Ruíz Brenda Elizabeth
Published: June 2022

En la actualidad, el uso de drogas sigue siendo un tema de relevancia para la sociedad, que afecta en mayor proporción a los hombres que a las mujeres, pero son los adolescentes el principal grupo de edad involucrado. Una de las drogas psicoactivas más potentes son las metanfetaminas, con un gran número de consumidores tanto a nivel nacional como internacional. Su consumo influye de forma oral y sistémica, por lo que se requiere una atención especial en esta población y la agudeza del médico para detectar cambios de comportamiento. El objetivo de este trabajo es mostrar clínicamente el caso de un paciente que consume metanfetaminas y el impacto que genera esta adicción a nivel dental, así como proporcionar herramientas referidas por varios autores para su mejor manejo en el consultorio
Prevalencia de gingivitis y caries en estudiantes universitarios mexiquenses con peso (no) saludable y su relación con consumo de azúcar
Authors: Laguna Camacho Antonio , Robles Navarro Julio B , Cruz Aburto María I , Arjona Serrano Judith , Hurtado Sánchez Quetzalcóatl
Published: June 2022

Objetivo: La gingivitis y caries son comunes en población mexicana, por lo que sus causas principales requieren identificarse para desarrollar intervenciones específicas. El presente estudio determinó la prevalencia de gingivitis y caries en jóvenes mexicanos con peso (no) saludable, y su relación con cepillado dental y consumo de azúcar. Material y métodos: Hombres y mujeres (18-25 años) con peso saludable (PS, n = 23, kg/m2 : 18.5-24.9) y no saludable (PNS, n = 23, kg/m2 : ≥ 30) fueron seleccionados por muestreo estratificado de una facultad universitaria. En una sesión se midió estatura, peso y grasa corporal del participante, se evaluó su dieta por recordatorio de 24 horas, y su salud oral por criterios de la OMS. Resultados: No difirió por condición de peso la prevalencia de gingivitis (PS = 74% vs. PNS = 70%) o caries (PS = 78% vs. PNS = 87%). Sólo una proporción menor de participantes reportó cepillarse los dientes una vez o más al día (PS = 22% vs. PNS = 30%). El porcentaje promedio de ingestión derivada de azúcar fue alto, pero no difirió por condición de peso (PS = 12% ± 10% vs. PNS = 11% ± 7%), y en todos los participantes se asoció positivamente con el índice de caries (r = 0.43, p < 0.01). Conclusiones: Las prevalencias de gingivitis y caries aquí encontradas fueron similares a las reportadas en otros estudios. Las acciones de protección a la salud oral continúan siendo necesarias en particular para promover menor consumo de azúcar entre estudiantes universitarios.
Corobamba: una reducción toledana (siglo XVI) del corregimiento de Paclas (en la actual provincia de Bongará, Amazonas-Perú)
Authors: Villar Quintana Anthony , Villar Sanchez Miuler
Published: June 2022

El presente artículo corresponde a una investigación inicial de tipo exploratoria en el sitio arqueológico de Corobamba, Perú, cuya finalidad correspondió a identificar ciertos aspectos de este lugar, como su filiación cultural y su funcionalidad. Para ello, se realizó un análisis tipológico de la planimetría del sitio, que además se apoyó en ciertos marcadores estilísticos de algunos objetos relacionados con dicho asentamiento. Además, recurrimos en gran parte a la información histórica, correspondiente a fuentes ya publicadas y a datos citados por otros investigadores que realizaron trabajos de archivo. De esta manera, logramos reconstruir, mediante una perspectiva diacrónica, algunos sucesos concernientes a dicho asentamiento, como su fundación durante la segunda mitad del siglo xvi para constituir una de las reducciones coloniales del corregimiento de Paclas (en el actual departamento de Amazonas, Perú), como parte de las políticas impuestas por el virrey Francisco de Toledo. Asimismo, también identificamos las actividades realizadas por los habitantes de Corobamba (incluyendo sus parcialidades), algunas políticas que afectaron a dichos individuos, los daños causados por parte de los colonizadores hispanos y, por último, el proceso de su abandono a causa de un sistema de reasentamientos dirigido por el obispo Baltasar Jaime Martínez Compañón, a fines del siglo xviii.
Design, Modeling and Analysis of Reciprocating Compressor
Authors: Jarang Hrishikesh Ganesh , Deshpande Dr. R. S.
Published: June 2022

Abstract: The present day concept of automation has increased the use of compressed air in every field of industrial life. To design double acting gas compressor with an intention to provide the operating pressure required for less time taken by single acting compressor to generate the same pressure of compressor. Basic components of double acting reciprocating gas compressor are designed. In this paper the process of reciprocating gas compressor from raw stage to the analyticalstage had been explained. In these process firstly to check the standard data and as per standard data the design calculation is being proceed. The aim of this topic is to know the effect on piston, connecting rod, piston head, and piston rod, guide way and may other components. We have limited standard bore size diameter reciprocating gas compressor cylinder so to get various bore size diameter for various place and for various uses for that reason to develop the compact size reciprocating gas compressor cylinder. So to get the proper results as per standarddata book need many research papers, books, and data so that it can be very helpful for designing and developing compact size reciprocating gas compressor cylinder. While designing the reciprocating cylinder one thing should be considered that is the capacity of gas tank should be measured, the standard cubic meter per hour (SCMH) should be known and to find out the SCMH valve we have to know the stroke length of reciprocating gas compressor. It means that for designing and making compressor firstly know the duty cycle and SCMH of reciprocating compressor. Keywords: Reciprocating Compressor, Natural Gas, Square Engine, Positive-displacement, Double-acting, Compressed gas
Smart White Cane
Authors: KamatIi Veer Chandra , Raj Abishek
Published: June 2022

Abstract: In this paper, I describe my own model of an ultrasonic blind walking stick with the use of Arduino that helps the visually impaired walk independently. According to the World Health Organization, 30 million people are completely blind, with 285 billion people suffering from vision impairment.[1] If u notice them, you can very well know about they can’t walk without the help of others. One has to ask for guidance to travel without hitting on an obstacle. A person can walk more confidently with this blind stick. This stick detects the object in front of the user and responds by vibrating or issuing a sound command to the user. As a result, the person can walk without stress. This device will be the best solution to overcome their either indoor or outdoor as its ranges can be adjusted from 2 feet to 8 feet distance using a switch. Keywords: Accuracy, Actuators, Handy, Ultrasonic sensor
Effect of Material Used for Infill Wall and Its Shape on the Seismic Performance of RC Frame
Authors: Kotadia Keny K. , Parikh Dr. K. B.
Published: June 2022

Abstract: RC frame structure is one of common used building structures. Previous studies show that infill wall significantly contribute to the seismic performance imposed on RC frame structure, increasing structural stiffness and hence leading to decrease structure's natural period. However under strong earthquake, infill wall not only holds up large lateral seismic force but also limits the deformation of beams and columns. In most of the previous studies on the behaviour of reinforce concrete building considering the effect of infill wall, rectangular shape of brick is taken into account. In this study, an attempt has been made to look over the effect of infill wall material type and its shape on the seismic performance of RC frame. This study will be restricted with single bay frame with two types of bricks a) Clay brick, b) Fly ash brick. The different shapes under consideration are rectangle and square. This study also contains the effect of size of infill wall units. The stress in concrete, lateral force resisting capacity and displacement results have been obtained by finite element analysis and compared for all the cases. Keywords: RC frame, Infill, Micro modelling, FEA, ABAQUS
Design and Development of Airfoil for Small Capacity Wind Turbine: A Review
Authors: Surve Mr. Minendra
Published: June 2022

Abstract— Renewable energy sources wind, solar is fast growing potential power across the world. Energy consumption and need is increasing day by day. Dependency on fossil fuel is not trail solution. Wind energy is one of the easy available renewable sources. Utilization of this energy into power generation will become good solution in futuristic energy crisis. We have named this as our final time design so as to begin allowing towards power generation through clean sources similar as wind. Power generation in our country is veritably low at present. In metropolises like Mumbai-India region are suffering from power cuts. The design of Wind Turbine blades, QBlade, solid work is used. It includes specific post processing and life assessment of blade. We take an occasion to present this report on design of airfoil and put before outline some useful information regarding this design. This work of art is motivated by the significant part of blades in the performance of wind turbine. This review helps researchers those who are working in the domain of micro-small capacity wind turbine. Keywords— Wind Turbine, Aerodynamics, Blade design, Airfoil, Micro-Small Capacity, QBlade
A Case Report of Korean Medicine Treatment for Post-Lumbar Puncture Headache
Authors: Oh Seo-hye , Park Eun-su , Kim Won-young , Kim Dong-young , Park Eun-young
Published: June 2022

Lumbar puncture is an essential procedure for obtaining fluid from spinal meningeal spaces, and post-lumbar puncture headache is the most frequent adverse event. This case report evaluates the effects of treatment with traditional Korean medicine on a patient suffering post-lumbar puncture headache using the Headache Disability Inventory (HDI) and the visual analog scale (VAS). The patient’s HDI score decreased from 46 to 6 after treatment, and the VAS score decreased from 62 to 5. The results suggest that traditional Korean medicine can be helpful in managing post-lumbar puncture headache.
A Case Report on Korean Medical Treatment for Delayed Neuropsychiatric Sequelae of Carbon Monoxide Poisoning
Authors: Jeong Sol , Jin Hyo-won , Hwang Ji-hyun , Bak Jeong-rim , Jeon Hye-soo , Moon Byung-soon , Yun Jong-min
Published: June 2022

Objective: This clinical study describes the effect of Korean medicine on a patient with Delayed Neuropsychiatric Sequelae after Carbon Monoxide Poisoning.Case presentation: A patient with the delayed neuropsychiatric effects of carbon monoxide exposure was treated with herbal medicine, acupuncture, moxibustion, and cupping. Clinical symptoms were measured with the Korean Mini Mental State Examination (K-MMSE), Functional Independence Measure (FIM), and the Modified Barthel Index (MBI). After 32 days of treatment, the patient’s K-MMSE score increased from 11 to 21 points, the FIM score from 52 to 94 points, and the MBI score from 46 to 84 points. There were no side effects.Conclusion: According to this case study, Korean medicine may be considered an effective treatment for delayed neuropsychiatric sequelae, although more studies are needed to confirm its validity.
A Case Report of Central Nervous System Disorder Induced Intractable Hiccups Treated with Korean Medicine
Authors: Moon Jiseong , Min Seonwoo , Kim Yeseul , Park Jiyoon , Hong Junghwa , Choi Dong-jun
Published: June 2022

Intractable hiccups are those which persist for more than one month and can often occur in patients with disorders of the central nervous system, such as stroke, epilepsy, or brain tumor. An 80-year-old male patient undergoing conservative hemodialysis for diabetic nephropathy, recently developed paralysis and dysphagia due to central nervous system complications including stroke and epilepsy. He was admitted to the ⃝⃝ Oriental Medicine Hospital, and treated with herbal medicine (Gyulpijugyeo-tang, Jeonssiigong-san, and Ijin-tang) and electrical acupuncture for 30 days. No side effects were observed during hospitalization. The frequency and duration of hiccups were measured daily and found to reduce, and the effect persisted during his admission. The patient took no other nervous system drugs. In conclusion, Korean medicine like gyulpijugyeo-tang and acupuncture can be effective for patients with intractable hiccups who cannot use alternative drugs or treatment, because of other complications.
A Case Report of the Korean Medical Treatment of Dysphagia and Anorexia after Lumbar Compression Fracture
Authors: Jo Hye-mi , Lee Eun-chang , Youn Hye-soo , Park Choong-hyun , Han Da-young , Jung Da-hae , Lee Jung-eun
Published: June 2022

Objective: The aim of this study is to describe the effects of traditional Korean medicine on a patient with dysphagia and anorexia following an acute lumbar compression fracture.Methods: The patient was treated with acupuncture and herbal medicine (Bojungikgi-tang and Insamyangyoung-tang), and the effects of the treatment were evaluated by monitoring oral feeding and using the Modified Barium Swallow (MBS) test.Results: After treatment, the amount of oral feeding more than doubled and the MBS was also improved.Conclusion: The results suggest that traditional Korean medicine may be effective for treating dysphagia and anorexia after an acute lumbar compression fracture.
A Case Report on Opioid-Induced Constipation in a Patient with Cancer Treated by Jowiseunggi-tang
Authors: Yoon Jee-Hyun , Park Su Bin , Kim Eun Hye , Lee Jee Young , Yoon Seong Woo
Published: June 2022

Objective: Jowiseunggi-tang (JWSGT) is a traditional herbal medicine commonly used for purgative activity in constipation. This study evaluates JWSGT for the treatment of opioid-induced constipation (OIC), the most common and debilitating gastrointestinal effect of opioid use.Methods: A 64-year-old man with floor of mouth cancer was hospitalized for OIC, and JWSGT was administered orally twice a day for 10 days, along with acupuncture, moxibustion, and cupping. The primary outcome measures were defecation type according to the Bristol Stool Form Scale (BSFS) and the frequency of bowel movements. The Brief Fatigue Inventory (BFI) and the Functional Assessment of Cancer Therapy-General (FACT-G) were used as secondary measures.Results: After three days of JWSGT administration, spontaneous bowel movements were observed two to three times per week with improved BSFS from type 2 to 4. A reduction in BFI score (8.7 to 2.0) and an increase in FACT-G score (44.3 to 59.0) suggested an improvement in fatigue level and quality of life.Conclusion: This is the first report to assess the efficacy of JWSGT for the management of OIC in patients with cancer, and JWSGT may be an effective option to improve symptoms and quality of life in this group.
A Case Report of Treating Hot Palms and Feet at Night with Sammulhwanggeum-tang
Authors: Kim Geun Young , Jung Somin , Ha Won Jung , Cho Ki-Ho , Moon Sang-Kwan , Jung Woo-Sang , Kwon Seungwon
Published: June 2022

Objective: The purpose of this study is to report the clinical treatment of a nighttime sensation of heat on the palms and soles of the feet of a 71-year-old female patient using Sammulhwanggeum-tang.Methods: Sammulhwanggeum-tang was administered for 19 days to reduce the patient’s symptoms, which were assessed using a visual analog scale (VAS) and by duration.Results: The heat sensation began to improve after four days and continued to do so for the subsequent 15 days. From May 12, X to May 30, X, the degree of subjective symptoms decreased from a VAS score of 10 before treatment to 0 after treatment, and their daily duration decreased from 10 to 0 hours. In addition, considering that the duration of the patient’s symptoms was about 30 days, the duration of the symptoms decreased to 17 days, including the period before the start of treatment.Conclusion: This clinical study suggests that Sammulhwanggeum-tang might be effective in resolving the sensation of heat on the palms and soles of the feet at night.
A Case of Insomnia with Pain after Discontinuation of Quetiapine Treated with Gilchogeun-dan
Authors: Lee Seong Wook , Park Hojung , Lee Da-Bin , Cho Ki-Ho , Moon Sang-Kwan , Jung Woo-Sang , Kwon Seungwon
Published: June 2022

Objective: This case report describes an 82-year-old man complaining of insomnia with pain after discontinuation of quetiapine.Methods: The patient was treated with the herbal extraction Gilchogeun-dan, and symptomatic improvement was assessed using the Korean version of the Pittsburgh Sleep Quality Index. Results: Following 28 days of Gilchogeun-dan treatment, the patient’s symptoms improved.Conclusions: This case suggests that Gilchogeun-dan could be effective in treating insomnia with pain through central nervous depressant activity and analgesic effect.
A Case Report on the Therapeutic Effect of Integrated Cancer Therapy for Glioblastoma Multiforme
Authors: Yang Jin-sung , Jang Hyuk-jun , Song Si-yeon , Park Ji-hye , Park So-jung , Yoo Hwa-seung
Published: June 2022

Objective: The purpose of this report is to present the effects of integrative cancer treatment (ICT) on a patient diagnosed with glioblastoma multiforme (GBM).Methods: A 71-year-old male GBM patient received ICT from May 14 to October 12, 2021 and concurrently received temozolomide and radiotherapy. The effect on symptoms was evaluated using a visual analog scale (VAS), and changes in tumor size were assessed using magnetic resonance imaging.Results: After treatment, the VAS score for nausea decreased from 5 to 1, and the tumor size also reduced.Conclusion: ICT could be effective in treating GBM patients by reducing the size of the tumor as well as alleviating the side effects.
Penyetaraan Wanita dengan Anjing di Depan Orang Salat: Sebuah Kajian Fiqh al-Hadis
Authors: Rahma Cut Wida , Yahya Agusni
Published: June 2022

A proper understanding of the traditions regarding the interruption of prayer due to the passage of a dog and a woman is a significant study, considering that this hadith seems insulting to women because the position of women is mentioned in this hadith lying down with dogs or equating human species with animal types. For this reason, this study will focus on looking at the meaning of the hadith when prayer is interrupted due to the crossing of a dog and a woman, what are the implications of these traditions for the validity of prayer, and what are the criteria for dogs and women in the hadith. The author uses a linguistic and socio-historical approach, using the science of fiqh al-Hadith as the main analytical tool. The results showed that from a linguistic and socio-historical point of view, the meaning of dog and woman is understood textually to mean that causing the prayer to be interrupted is to destroy the prayer or cancel the prayer, while contextual understanding means that it is a symbol that can reduce the busyness of prayer. The implication of fiqh al-Hadith is textual means to break the prayer or cancel the prayer, while contextually it means reducing the solemnity of prayer or the value of the quality of prayer, not canceling the prayer. The criteria for the dog in the hadith are a black dog which is linguistically a symbol of Satan and a woman who has reached puberty as a temptress for those who look at her. Pemahaman yang tepat terhadap hadis-hadis tentang terputusnya salat karena melintasnya anjing dan wanita merupakan suatu kajian yang signifikan, mengingat hadis ini terkesan menghina kaum wanita, karena posisi wanita disebut di dalam hadis ini berbaringan dengan anjing atau penyamaan jenis manusia dengan jenis binatang. Tulisan ini akan fokus melihat bagaimana maksud hadis terputusnya salat karena dilintasi anjing dan wanita, bagaimana implikasi hadis-hadis tersebut terhadap sahnya ibadah salat, dan bagaimana kriteria anjing dan wanita dalam hadis tersebut. Penulis menggunakan pendekatan linguistik dan sosio-historis, dengan menggunakan ilmu fiqh al-Hadis sebagai alat analisis utama. Hasil penelitian menunjukkan bahwa ditinjau dari sisi kebahasaan dan sosio-historis, pemaknaan anjing dan wanita jikan dipahami secara tekstual berarti menyebabkan terputusnya salat adalah merusak salat atau membatalkan salat, sedangkan secara kontekstual berarti sebagai simbol yang dapat mengurangi kekusyukan salat. Implikasi fiqh al-Hadis secara tekstual berarti membatalkan salat, sementara secara kontekstual berarti mengurangi kekusyukan salat atau nilai kualitas salat bukan membatalkan salat. Kriteria anjing dalam hadis tersebut adalah anjing hitam yang secara linguistik sebagai simbol dari setan dan wanita yang sudah baligh sebagai penggoda bagi orang yang memandang kepadanya.