bluuebunny/crossref_metadata_2025 huggingface dataset:
Del mercadeo transaccional al mercadeo relacional para construir comunidad en los docentes universitarios
Authors: Gómez-Bayona Ledy , Zuluaga-Girón Laura , Palacio López Sandra Milena , Arrubla-Zapata Juan Pablo , Moreno-López Gustavo
Published: December 2022

El mercadeo transaccional se ha venido transformando en mercadeo relacional en los modelos de gestión de las universidades, el objetivo principal de esta investigación es establecer la relación entre las principales variables del mercadeo relacional: confianza, satisfacción y lealtad para construir comunidad en los docentes universitarios. La metodología utilizada es cuantitativa, con una muestra de 287 docentes pertenecientes a universidades acreditadas institucionalmente en la ciudad de Medellín, Colombia. Como resultado se obtiene que se deben construir estrategias para consolidar la confianza, ya que esta es la base de todo relacionamiento. El nivel de satisfacción es adecuado, sin embargo, no necesariamente conduce a la lealtad de los docentes en las instituciones. Se valora positivamente el relacionamiento para fortalecer y consolidar propuestas de valor. Los docentes consideran que se cuenta con buen ambiente para la proyección personal y profesional, ya que influye significativa en la confianza y en la satisfacción.
Tejido empresarial del departamento de Bolívar: baremación a través de la analítica de datos
Authors: Arboleda Mazo Walter Hugo , García Arango David Alberto
Published: December 2022

El presente artículo incluye una descripción de los resultados obtenidos de aplicar analítica de datos a la clasificación de empresas con potencial innovador del departamento de Bolívar. Diversas son las clasificaciones que pueden hacerse a este respecto; en el presente texto se pondrá a consideración una estrategia para clasificar el ecosistema empresarial anteriormente mencionado tomando como referencia la aplicación de analítica para la clasificación de 6.703 empresas del departamento de Bolívar en términos del promedio de ingresos operacionales y otras variables relacionadas, con la finalidad de identificar el potencial de éstas en el marco del tejido empresarial del departamento.El desarrollo de la investigación permitió identificar 1.098 empresas con potencial de capacidades en innovación agrupadas en 42 clústeres. Los resultados aportan a la comprensión de las características del tejido empresarial para una posterior formación y capacitación que posibilite un mejoramiento de capacidades en el sector.
Paramilitarismo en Colombia y el debilitamiento del Estado: caso de estudio en el municipio de Segovia, Antioquia
Authors: Piedrahita Lemy Bran , Lillian Johansson Sandra
Published: December 2022

El debilitamiento del Estado no está supeditado exclusivamente a la existencia de políticas desiguales, funcionarios poco calificados o con prácticas corruptas, sino también a la presencia de otros actores que compiten con la institucionalidad en el ejercicio del poder. Lo que en un escenario como el colombiano se ha visto reflejado en la confluencia de diversos actores armados que ejercen un «cogobierno» de los territorios en simultáneo con el Estado.Como objetivo se describirá de qué manera se refleja el debilitamiento del Estado por la incidencia de movimientos paramilitares en el municipio de Segovia, del departamento de Antioquia. Para esto se realizó un estudio bajo un enfoque cualitativo de alcance descriptivo, conducido a partir de tres momentos que incluyeron: la revisión de literatura especializada, análisis de prensa y entrevistas semiestructuradas con habitantes del territorio; empleando para el análisis herramientas teóricas derivadas de la hermenéutica. Como resultado el estudio evidencia que el debilitamiento del Estado está vinculado con la existencia de economías mineras en el territorio, así como la fragilidad de las instituciones en el ámbito local y las prácticas de corrupción, siendo identificados tanto en el proceso de revisión de literatura como en las entrevistas sostenidas con los informantes clave.Por tanto, para fortalecer el Estado en el nivel local es preciso afianzar no solo las capacidades en términos de defensa dentro de los territorios, sino también incluir una visión integral que involucre elementos socioculturales que debido al accionar de movimientos paramilitares debilitan el Estado colombiano.
PEMERANAN TOKOH TRISNO DALAM PERTUNJUKAN NASKAH TITIK-TITIK HITAM KARYA NASYAH DJAMIN
Authors: Agu Renaldy Ricky
Published: December 2022

Pemeran menggunakan metode akting Stanislavsky untuk pendekatan terhadap akting realis dalam memerankan tokoh Trisno. Capaian dari metode akting ini adalah mewujudkan yang natural dan tidak di buat-buat. Penciptaan pemeranan ini menggunakan dua teori, yaitu: teori Sense of Memory dari Stanislavsky dan teori spiritual akting dari WS Rendra. Tahapan untuk memerankan tokoh Trisno dimulai dari tahap membaca naskah, membangun khimestry dan menjalin relasi dengan tata pentas, tata rias, tata busana dan tata musik.
On Solutions to the Diophantine Equations p x + q y = z 3 when p ≥ 2,q are Primes and 1 ≤ x,y ≤ 2 are Integers
Authors: Burshtein Nechemia
Published: December 2022

In this article we consider the equations p x + q y = z 3 in which p ≥ 2, q are distinct primes, z is a positive integer and the integers x, y satisfy 1 ≤ x,y ≤ 2. The following three cases are examined, namely x = y = 2, x = y = 1, x = 1 and y = 2, when p ≥ 2, q are primes. All the possibilities are determined for infinitely many solutions, unique solutions and cases of no solutions.
Solutions of the Diophantine Equations p x + (p + 1)y + (p + 2)z = M 2 for Primes p ≥ 2 when 1 ≤ x, y, z ≤ 2
Authors: Burshtein Nechemia
Published: December 2022

In this article, we investigate the solutions of the Diophantine equations p x + (p + 1)y + (p + 2)z = M 2 for primes p ≥ 2 when 1 ≤ x, y, z ≤ 2. We establish : (i) When p = 2 and x = y = z = 1, the equation has a unique solution. (ii) When p = 4N + 1 and 1 ≤ x, y, z ≤ 2, the equations have no solutions. (iii) When p = 4N + 3 and x = y = z = 1, the equation has infinitely many solutions. (iv) When 3 ≤ p ≤ 199 and x = 1, y = z = 2, the equation has exactly one solution. (v) In all other cases 1 ≤ x, y, z ≤ 2 which are not mentioned above, the equations have no solutions.
Common Fixed Point Theorems for Six Self-Maps in G-Metric Spaces
Authors: V.Nagaraju
Published: December 2022

In this paper, we define generalized weakly contractive mappings and prove two common fixed point theorems for six self maps in G-metric spaces. Using the notions of common limit in the range property and weakly compatibility, the first theorem is proved whereas occasionally weakly compatibility is used in the second theorem. We also deduce some common fixed point theorems for four self maps. Our results improve and extend some metric fixed point results in the literature.
On Star-critical (K1,n, K1,m + e) Ramsey Numbers
Authors: Jayawardene C.J. , Senadheera J.N. , Fernando K.A.S.N. , Navaratna W.C.W.
Published: December 2022

We say that Kn → (G,H), if for every red/blue colouring of edges of the complete graph Kn, there exists a red copy of G, or a blue copy of H in the colouring of Kn. The Ramsey number r(G,H) is the smallest positive integer n such that Kn → (G,H). Let r(n,m)=r(Kn, Km). A closely related concept of Ramsey numbers is the Star-critical Ramsey number r*(G, H) defined as the largest value of k such that K r(G,H)-1 ˅ K 1,k → (G,H). Literature on survey papers in this area reveals many unsolved problems related to these numbers. One of these problems is the calculation of Ramsey numbers for certain classes of graphs. The primary objective of this paper is to calculate the Star critical Ramsey numbers for the case of Stars versus K1,m+e. The methodology that we follow in solving this problem is to first find a closed form for the Ramsey number r*(K1,n , K1,m+e) for all n, m ≥ 3. Based on the values of r*(K1,n , K1,m+e) for different n, m we arrive at a general formula for r*(K1,n , K1,m+e). Henceforth, we show that r*(K1,n , K1,m+e) = n+m-1 is defined by a piecewise function related to the three disjoint cases of n, m both even and n ≤ m - 2, n or m is odd and n ≤ m-2 and n > m-2.
Computation of Minus F-indices and their Polynomials of Titania Nanotubes
Authors: Kulli V.R.
Published: December 2022

In Chemical Graph Theory, a forgotten topological index or F-index has significant importance to collect information about properties of chemical compounds. In this study, we introduce the modified minus F-index, minus connectivity F-index, reciprocal minus connectivity F-index, general minus F-index and their polynomials of a molecular graph. Furthermore, we present exact expressions for these minus F-indices and their polynomials of titania nanotubes.
The Mathematical Description of Homogeneous Turbulence for Incompressible Fluids
Authors: Rivera Javier
Published: December 2022

The present article establishes the mathematical description of turbulence for incompressible fluids as a response to an important question: “Is a complete mathematical description of turbulence possible?” in ResearchGate.net website discussion started August 26, 2018. Since inhomogeneous turbulence is too complex, this article will limit the discussion to homogeneous turbulence. This article provides the necessary propositions for a mathematical description of homogeneous turbulence for incompressible fluids which is achievable via a probabilistic formulation, deterministic chaos, and the Kolmogorov’s -5/3 law.
The Existence of Positive Solutions for Third-Order Three-Point Nonhomogeneous Boundary Value Problems
Authors: Da Jiali
Published: December 2022

In this paper, we investigate the existence of positive solutions for third-order three-point nonhomogeneous boundary value problems. By using Leray-Schauder fix point theorem, some sufficient conditions for the existence of positive solutions are obtained, which improve the previous results.
On the Non-Linear Diophantine Equation 𝒑 𝒙 + (𝒑 + 𝟒 𝒏) 𝒚 = 𝒛 𝟐 where p and 𝒑 + 𝟒 𝒏 are Primes
Authors: Moonchaisook Vipawadee
Published: December 2022

In this paper, we consider the non-linear Diophantine equation 𝑝 𝑥 + (𝑝 + 4 𝑛) 𝑦 = 𝑧 2 , where 𝑝 > 3, 𝑝 + 4 𝑛 are primes, x, y and z are nonnegative integers and n is a natural number. It is shown that this non-linear Diophantine equation has no solution.
Diametral Covering Number of a Graph
Authors: Huilgol Medha Itagi , Kiran S
Published: December 2022

In this paper, we introduce the diametral covering number of a graph. A subset S of V(G) is said to be a diametral cover for G if every diametral path of G contains at least one vertex of S. The minimum cardinality of S taken over all diametral covers is called the diametral covering number of G and is denoted by σd(G). Here we have given the diametral covering number of several classes of graphs and have given bounds for the same in terms of basic graph parameters. Also, a characterization of graphs having particular diametral covering number is given.
Thermal effect on the design loads of Multi-Story R.C. Buildings on Sloped Terrain in Saudi Arabia
Authors: Laissy M. Y.
Published: December 2022

Reinforced concrete Structures are subjected to temperature changes
daily and seasonal this is besides the live and dead loads applied to
the building the changes in the temperature consequently produce
temperature loads due to their interaction with the surrounding
environment as well as the solar radiation exposure of the building.
Such temperature loadings consequently lead to thermal stresses in most
structural elements. These thermal loads will produce thermal stresses
that can be considered comparable to or sometimes exceed the stresses of
the dead and live loading due to insufficient thermal insulation which
may lead to severe structural elements damage if it is not considered in
the design phase. This paper presents a study of the effect of thermal
loads on multi-story RC. buildings in Saudi Arabia with fixed and hinged
support constraints with and without bracing system under seismic loads
on sloped terrain. RC. buildings have a high vulnerability when designed
on sloped terrains due to the mass and vertical irregularity that will
increase the values of shear forces and torsional moments on the
building. This work attempts to study the building’s behavior on sloped
terrain under the effect of thermal loads using ETABS V18.1. Etabs
Models were analyzed to present the effect of thermal loads
concentrating on the displacement, drift, deformations, and base shear.
A comparison of digestive strategies for fishes with different feeding habits: digestive enzyme activities, intestinal morphology and gut microbiota
Authors: Jiao Fang , Zhang Lei , Limbu Samwel Mchele , Rong hua
Published: December 2022

Feeding habit determines the digestive tract structure and intestinal
microflora. However, the relationship among feeding habit, digestive
physiology intestinal, and microbial diversity of omnivorous,
herbivorous, filter-feeder and carnivorous fish reared in the same pond
has not been compared. This study compared the digestive enzyme
activities, intestinal morphology and intestinal microflora of
omnivorous (Carassius auratus), herbivorous (Ctenopharyngodon idellus),
carnivorous (Siniperca chuatsi) and filter-feeder (Shizothorax grahami)
and predicted the potential functions of specific microflora on
different nutrients. Twelve intestine samples were collected from each
of the four fishes from Dianchi Lake. The composition and diversity of
microbial communities were determined by using high throughput
sequencing of 16S rDNA. The results showed that the filter-feeder fish
had significantly higher protease but lower amylase activities in the
intestine than herbivorous. The carnivorous fish intestine had more
microvilli branches and complex structures than other fish species in
the order carnivorous > herbivorous >
filter-feeder > omnivorous. The diversity of intestinal
microflora was higher in omnivorous and followed the order omnivorous
> herbivorous > filter-feeder >
carnivorous. Acinetobacter species and Bacteroides species were the most
dominant flora in carnivorous and herbivorous fish, respectively.
Acinetobacter johnsonii, Acinetobacter lwoffii and Pseudomonas stutzeri
might help the host to digest protein, while Bacteroidetes species may
help the host to digest cellulose. Taken together, feeding habit
determines the digestive enzyme activities, intestinal tissue morphology
and differential colonization of fish intestinal flora. The knowledge
obtained is useful in designing appropriate approaches for feed
formulation and feeding practices in for fish.
Detecting the imprints of past clear-cutting on riparian forest plant communities along a Mediterranean river
Authors: Simone Leopoldo de , Angiolini Claudia , Fiaschi Tiberio , Cifaldi Giuseppe Pio , Maccherini Simona , Fanfarillo Emanuele
Published: December 2022

In riparian forests, clear-cutting causes long-lasting changes in both
riparian and aquatic biota. In this work, we examined if past
clear-cutting events occurred at different times have imprints on
riparian forests in a Mediterranean river in central Italy. We carried
out a randomized, plot-based vegetation survey of riparian forests in
systematically sampled 500 m-long sectors along the whole river,
dividing the riparian zone into two internal and two external strips.
From historical aerial photos, past clear-cutting events within plots
were detected and classified in age classes: i) cut in the past 8 years
(recent); ii) cut between 8 and 19 years ago (intermediate); iii) no
signs of clear-cutting in the last 19 years (distant). We analyzed the
responses of vegetation to clear-cutting and strip position. Alien
species richness increased and woody species richness decreased in
recently clear-cut areas compared to those with a distant clear-cutting
event. Moreover, recently cut woods showed an increase in alien and
synanthropic species. Intermediate clear-cut areas had higher levels of
invasion by alien species compared to areas with distant cut. Riparian
forests of internal strips are impacted by clear-cutting, but seem to
recover in 8-19 years thanks to their natural resilience. Conversely,
recent or intermediate clear-cutting events did not affect any of the
investigated vegetation attributes in the external strips since such
forests were already invaded by Robinia pseudoacacia after human
disturbance. Our results confirm that clear-cutting events can have
long-lasting effects on Mediterranean riparian forests, confirming the
vulnerability of river ecosystems to clear-cutting and suggesting the
need for more caution in management practices to improve the
conservation status of riparian forests.
DNA sensing in the pathological process of ischemic stroke
Authors: Zhang ShiWen , Wu ChaoRan , Liao Hong
Published: December 2022

The innate immune response plays an important role in the pathological
process of ischemic stroke. Increasing evidence suggests that the
inflammatory response triggered by the innate immune system hinders
neurological and behavioral recovery after stroke. The perception of
abnormal DNA and its downstream effects are an important part of the
innate immune system. The abnormal DNA is the major inducing factor for
innate immune response and is sensed by a series of DNA sensors. In this
review, we discussed the multiple roles of DNA sensing in the
pathological process of ischemic stroke, with a special focus on DNA
sensors Toll-like receptor 9 (TLR9), absent in melanoma 2 (AIM2) and
cyclic GMP-AMP synthase (cGAS).
Maturity Grading of Jujube for Industrial Applications Harnessing Deep Learning
Authors: Mahmood Atif , Tiwari Amod Kumar , Singh Sanjay Kumar , Ali Mohd. Mohsin
Published: December 2022

Jujube is one of the popular fruits that possess high nutritional
components and have economic value. Grading of jujube is a post-harvest
process applied in the fruit industry for the tasks like fruit quality
check, fruit species identification, price labelling, edibility duration
estimation, safety, etc. This research investigates into the suggested
7-layer CNN model and two classical models (i.e., VGG16 and AlexNet) for
grading jujube fruits according to their stages of maturity. Primarily,
jujube of four different maturity grades was identified on the field and
collected from the field manually and their images were captured through
a machine vision system. Further, image pre-processing and augmentation
were performed to get the training/testing-ready dataset. Finally, a
7-layer CNN model was deployed and grading performance was examined over
the original and augmented dataset using performance metrics of
precision, sensitivity, and F1-measure. Furthermore, the model’s
classification accuracy was compared to that of classical models, where
the proposed model surmounts both the classical models. Results reveal
that the proposed model attained a high grading accuracy of 99.44% and
97.53% over the augmented and original dataset respectively. Also, the
computation time and training parameters count were reduced to almost
one-tenth and one-third of that of VGG16 and AlexNet models. Results
advocate that the classical model could be replaced with the proposed
models and can be further investigated for other fruits for better
classification accuracy, reduced parameters and reduced computational
time.
Strategyproof and Fair Matching Mechanism for Union of Symmetric M-convex Constraints
Authors: Yahiro Kentaro , Barrot Nathanaël , Yokoo Makoto , Zhang Yuzhe
Published: December 2022

We identify a new class of distributional constraints defined as a union
of symmetric M-convex sets, which can represent a variety of real-life
constraints in two-sided matching settings. Since M-convexity is not
closed under union, a union of symmetric M-convex sets does not belong
to this well-behaved class of constraints. Therefore, developing a fair
and strategyproof mechanism that can handle this class is challenging.
We present a novel mechanism for it called Quota Reduction Deferred
Acceptance (QRDA), which repeatedly applies the standard Deferred
Acceptance mechanism by sequentially reducing artificially introduced
maximum quotas. We show that QRDA is fair and strategyproof when
handling a union of symmetric M-convex sets, which extends previous
results obtained for a subclass of the union of symmetric M-convex sets:
ratio constraints. QRDA always yields a weakly better matching for
students than a baseline mechanism called Artificial Cap Deferred
Acceptance (ACDA). We also experimentally show that QRDA performs better
in terms of nonwastefulness than ACDA.
7,8-dihydroxyflavone displayed antioxidant effect through activating HO-1 expression and inhibiting caspase-3/PARP activation in RAW264.7 cells
Authors: Tang You-Zhi , Chen Ting-Xiao , Wang Shou-Kai , Zhang Yu-Qing , Wang Wei , Wang Qi , Yu Jian-Chun , Zhao Sheng-Chen , Xi Gao-Lei , Jin Zhen , Chen Ze-Shao
Published: December 2022

Flavonoids, contain a benzo-γ-pyrone (C6–C3–C6) skeleton, have been
reported to exhibit effective antioxidant ability. This study aimed to
compare the antioxidant activities of 7,8-dihydroxyflavone (7,8-DHF) and
7-hydroxyflavone (7-HF) in H O , LPS,
or t-BHP-induced RAW264.7 cells, respectively. The antioxidant
capacities of 7,8-DHF and 7-HF were firstly evaluated by
2,2-azinobis-3-ethyl-benzothiazoline-6-sulphonic acid (ABTS),
2,2-diphenyl-1-picrylhydrazyl (DPPH) and ferric reducing antioxidant
power (FRAP) assays. Then, ROS, SOD, and MDA productions in H
O , LPS, or t-BHP-induced RAW264.7
cells were tested and compared, respectively. Finally, the antioxidant
mechanisms of 7-HF and 7,8-DHF were initially investigated by western
blot. Our results showed that 7,8-DHF possessed stronger free-radical
scavenging capacity than 7-HF. Both 7,8-DHF and 7-HF suppressed MDA
production and ROS accumulation, improved the activity of SOD in H
O , LPS, or t-BHP-induced RAW264.7
cells, respectively. And 7,8-DHF exerted better antioxidant effect than
7-HF, especially in t-BHP-induced oxidative stress. Mechanically,
7,8-DHF prevented the activation of PARP and caspase-3, meanwhile
markedly upregulated the expression of HO-1 protein in t-BHP-induced
oxidative stress. These results suggested that 7,8-DHF might be served
as potential pharmaceutical drug against oxidative stress injury.
Regulation of the oxidase mimetic activity of ceria nanoparticles by buffer composition
Authors: Wu Yonghui , Yang Lu , Wu Qianqian , Liu Qingshan , Zou Ling , Yang Xiaochao , Tang Keyong
Published: December 2022

Ceria nanoparticles (CNPs) is an important typical nanozyme with
multiple enzyme mimetic activities, which could facilitate the oxidation
of organic dyes in acidic conditions, because of the oxidase mimetic
activity. Usually, the regulation of oxidase mimetic activity is focused
on the adjustment of the structure, morphology, composition, surface,
and other factors of nanozymes. However, the influence of the
surrounding environment is not considered, which is very important
during the reaction process. In this work, the oxidase mimetic activity
of CNPs in buffer solutions including citric acid, acetic acid and
glycine buffer solutions was investigated, with the results that
carboxyl group in buffer solution could adsorb the CNPs on the surface
to promote the oxidase mimetic activity. Due to the chelation with
cerium ion, the enhancement is more significant by molecules with
polycarboxylic groups, and the enhancement is more efficient by carboxyl
molecules in buffer solution, compared with the modification of the
carboxyl groups on the surface, because of the easier operation and
smaller steric hindrance. From viewpoint of increasing the oxidase
mimetic activity of CNPs, the work is expected to provide references for
the selection of the reaction system to optimize the oxidase mimetic
activity in bio-detection application.
COVID-19 Hesitancy and Vaccine Attitudes among African American and Nigerian College Students
Authors: Smith Calvin , Okeke Kizito , Ebeh Joy Eleojo , Amhanesi John
Published: December 2022

This cross-sectional study examined COVID-19 attitudes and vaccine
hesitancy among African American and Nigerian college students (
N = 189). African American and Nigerian college students were
sampled from regional universities within the United States and Nigeria.
Participants completed the World Health Organization (WHO) Vaccine
Hesitancy Scale (VHS; 2014) and sociodemographic questions to assess
attitudes, primarily vaccination hesitancy, toward COVID-19 vaccination.
Independent t tests revealed no significant differences between
the nationalities and any hesitancy in taking the COVID-19 vaccine (
t(167) = .334, p = .739). However, there was a significant
effect for trust in the COVID-19 vaccine ( t(174) = -3.42,
p = <.001), with American students ( M = 0.59;
SD = 0.50) showing more trust than Nigerian students ( M =
0.34; SD = 0.48). In addition, there was a significant effect for
the overall general support of vaccines, t(176) = 2.43 p =
.016, with Nigerian students ( M = 0.86; SD = 0.35)
showing more favor than American students ( M = 0.71; SD =
0.46). Additional analyses associated with the cross-cultural
comparisons were conducted and discussed.
Profit versus Social Impact and Responsibility
Authors: Skorin-Kapov Jadranka , Tagangylyjov Jovher
Published: December 2022

The complexities of contemporary professional and business environments
mandate us to discuss and then take a stance towards various issues
arising in transactions between the providers of service or products and
the recipients (customers, shareholders, stakeholders). Relationships
include the interactions of a business with natural and man-made
environments (natural resources and competition, respectively). While
traditionally businesses were driven more by shareholders than
stakeholders, current situation with climate change, pollution, social
unrests, inequity, and globalization requires bigger stakeholders’
consideration. This trend led to creation of PBC-corporations, or Public
Benefit Corporations pledging for bigger environmental and societal
awareness. One of the public benefit corporations that are operating
within New York State and locally on Long Island is the Long Island
Power Authority (LIPA). During this research, the PSEG-LIPA
representatives were contacted to get some insight information about
their operations and what is the role of stakeholder considerations in
their planning.
De alfa a omega: Estimación de la confiabilidad ordinal. Una guía práctica
Authors: Vizioli Nicolás , Pagano Alejandro
Published: December 2022

La presente investigación realiza un recorrido por el concepto de confiabilidad como una de las propiedades psicométricas fundamentales en la Teoría Clásica de los Test. Se desarrolla el concepto y cuáles son sus diferentes aplicaciones prácticas para indagar el grado de confiabilidad de un instrumento de medición. Se centra el estudio en el cálculo de la consistencia interna a partir del alfa y el omega como los coeficientes más utilizados y la importancia de calcularlos mediante la utilización de matrices de correlaciones policoricas (MCP). Como objetivo principal se presenta una guía en español para el cálculo de coeficientes ordinales de confiabilidad al utilizar el programa R/RStudio. Se brinda un ejemplo a nivel empírico que da cuenta la relevancia de calcular este tipo de coeficientes para el cálculo de la confiabilidad de un instrumento. Al emplear una muestra de 266 adultos entre 18 y 63 años (M = 31.91, DE = 11.50), se administró la versión adaptada a argentina del Inventario de Ansiedad de Beck y el Cuestionario de Regulación Emocional. De esta manera, se exponen coeficientes para estimar la confiabilidad de los instrumentos que dan cuenta de sus ventajas y desventajas, al realizar el cálculo mediante MCP, matriz de correlaciones de Pearson y matriz de covarianzas de Pearson. A partir de los resultados, se evidencia que el cálculo mediante MCP proporcionó grados de confiabilidades mayores respecto al cálculo mediante las otras dos matrices. Se espera que el presente documento sea de importancia para investigadores no familiarizados con R.
Experimental Investigation of Al2O3 Nanofluid for Thermal Energy Management of Microchannel Heat Sink
Authors: Aglawe Kapil , Yadav Ravindra , Thool Sanjeev
Published: December 2022

Energy is one of the primary foundations supporting evolutionary changes. Heat transfer is improved by increasing the surface area density and/or changing the base fluid characteristics. Because of its small size and improved heat transfer properties, nanofluid cooled microchannel heat sinks (MCHS) have lately become a popular choice for electronics and thermal applications. The influence of employing nanofluids for cooling a chip was investigated experimentally in this work to evaluate the heat transfer characteristics. The investigations were carried out in order to confirm the influence of nanofluid concentration and wall temperature upon thermal-hydraulic properties of the microchannel heat sink. In present study, Al2O3 water nanofluid was employed, with 0.1, 0.2, 0.3, 0.4, and 0.5% nanoparticle volume fractions, mass flow rate (MFL) 2, 5, and 8 m/s at 25, 30 and 35oC inlet tempreture. The resulting experimental findings was verified from results obtained by other researchers, which showed important correlation. The heat transfer efficacy of electronics cooling systems has been enhanced by the nanofluid technology and the configuration of the rectangular heat sink.
COESÃO E INCLUSÃO SOCIAL COMO POLÍTICA NO/DO CHILE PARA O ENSINO DE CIÊNCIAS NATURAIS
Authors: Castillo Trittini Soledad Andrea , Dias Rosanne Evangelista
Published: December 2022

O ensino de ciências no 1º ciclo do ensino fundamental do Chile vem, nas últimas duas décadas, produzindo sentidos em torno de demandas de coesão, equidade e integração social como tentativa de alcançar melhores resultados no desempenho escolar e no alcance da qualidade escolar. Neste artigo, partindo de uma abordagem discursiva apoiadas em pesquisas de Lopes e Macedo para as políticas de currículo, buscamos interpretar os textos produzidos nos documentos curriculares para problematizar a produção de sentidos sobre o ensino de ciências associado à ideia de progresso e adaptabilidade dos sujeitos, eixos centrais nas reformas educativas chilenas. Neles, a ciência é significada como estratégia, não apenas para descobrir e compreender o conhecimento científico, como também para adquirir competências para o desenvolvimento social dos estudantes.
OBSTÁCULOS EPISTEMOLÓGICOS EM ATIVIDADES EXPERIMENTAIS RELACIONADAS A CONCEITOS DE FÍSICA DA REVISTA CIÊNCIA HOJE DAS CRIANÇAS
Authors: Martins Jéssica Taynara , Florentino de Melo Viviane , Oliveira Elrismar Gomes
Published: December 2022

Neste artigo, apresentamos os resultados de uma pesquisa que se propôs a identificar atividades experimentais relacionadas a conceitos de Física da revista Ciência Hoje das Crianças (CHC), que podem suscitar obstáculos epistemológicos. O aporte teórico bachelardiano foi adotado por seu potencial para provocar reflexões críticas para a análise de materiais que publicam informações sobre Ciência. Assim, com base na metodologia da análise de conteúdo, analisamos atividades experimentais da CHC das edições do período de 2009 a 2020. Os resultados mostram que, de 66 propostas experimentais de Física da revista, 20 podem suscitar obstáculos epistemológicos. O obstáculo epistemológico mais identificado foi o obstáculo verbal e o de menor frequência foi o realista. Os obstáculos quantitativo e pragmático não foram encontrados nas atividades experimentais analisadas. Compreendemos, a partir dos resultados, que essas atividades necessitam da intervenção do professor na identificação e na superação dos obstáculos epistemológicos, para que a sua realização possa ser potencializada.
ANÁLISIS DEL RAZONAMIENTO PROBABILÍSTICO EN FUTUROS PROFESORES DE CIENCIAS
Authors: Méndez-Hincapié Néstor , Garzón-Barragán Isabel , Castro-Moreno Julio Alejandro
Published: December 2022

Este artículo indaga los modos de razonar de un grupo de estudiantes, futuros profesores de ciencias, de las licenciaturas en física, química y biología de la Universidad Pedagógica Nacional de Colombia, al abordar tres situaciones problemáticas cuyo análisis implica hacer uso de conceptos básicos de probabilidad, como independencia de eventos y nociones de conteo. Cabe señalar que esta investigación hace parte del desarrollo de la tesis doctoral del primer autor. El análisis de los modos de razonar de los estudiantes expresado en sus respuestas, se lleva a cabo considerando como marco teórico el estilo de razonamiento probabilístico, uno de los seis estilos de razonamiento científico propuestos en el enfoque filosófico de Ian Hacking. Y, para establecer los diferentes modos de razonar se emplean los criterios de la metodología fenomenográfica, la cual permite expresar estos modos en la forma de categorías de descripción que tienen como referente el conocimiento científico vigente. Los resultados obtenidos permiten poner en evidencia que un gran número de estudiantes hacen razonamientos probabilísticos incipientes; se identifican sesgos como la falacia del apostador, la aplicación de la probabilidad frecuencial a pocos datos, y la prevalencia del pensamiento determinista. Estas falencias constituyen una limitante al abordar el estudio de teorías científicas, como la mecánica cuántica o la evolución de las especies, en las cuales es primordial llevar a cabo razonamientos de tipo probabilístico para comprenderlas.
Dificultades percibidas por el profesorado de secundaria en el desarrollo de actividades científicas no formales
Authors: Martín-García Jorge , Dies Álvarez María Eugenia
Published: December 2022

La continua expansión de la educación no formal hace necesario abordar la evaluación de estos contextos para que los educadores puedan obtener de ellos el máximo rendimiento. En esta línea, este trabajo presenta una evaluación preliminar de las dificultades que, de acuerdo con el profesorado, encuentran los estudiantes en el desarrollo de una actividad científica no formal. Las respuestas de los docentes a un cuestionario de preguntas abiertas revelaron la existencia de cinco grandes tipos de dificultades vinculadas preferentemente a la mecánica de trabajo más abierta y competencial que promueve la propuesta. En este sentido, se concluye que existe la necesidad de proporcionar oportunidades para el desarrollo de proyectos de investigación en la ciencia escolar y para la promoción de las competencias clave, aspectos en los que los contextos no formales pueden convertirse en recursos de gran utilidad.
Diabetes, Atherosclerosis, and Stenosis by AI
Authors: Jonas Rebecca A. , Crabtree Tami R. , Jennings Robert S. , Marques Hugo , Katz Richard J. , Chang Hyuk-Jae , Stuijfzand Wijnand J. , van Rosendael Alexander R. , Choi Jung Hyun , Doh Joon-Hyung , Her Ae-Young , Koo Bon-Kwon , Nam Chang-Wook , Park Hyung-Bok , Shin Sang-Hoon , Cole Jason , Gimelli Alessia , Khan Muhammad Akram , Lu Bin , Gao Yang , Nabi Faisal , Nakazato Ryo , Schoepf U. Joseph , Driessen Roel S. , Bom Michiel J. , Thompson Randall C. , Jang James J. , Ridner Michael , Rowan Chris , Avelar Erick , Généreux Philippe , Knaapen Paul , de Waard Guus A. , Pontone Gianluca , Andreini Daniele , Al-Mallah Mouaz H. , Guglielmo Marco , Bax Jeroen J. , Earls James P. , Min James K. , Choi Andrew D. , Villines Todd C.
Published: December 2022

OBJECTIVE

This study evaluates the relationship between atherosclerotic plaque characteristics (APCs) and angiographic stenosis severity in patients with and without diabetes. Whether APCs differ based on lesion severity and diabetes status is unknown.

RESEARCH DESIGN AND METHODS

We retrospectively evaluated 303 subjects from the Computed TomogRaphic Evaluation of Atherosclerotic Determinants of Myocardial IsChEmia (CREDENCE) trial referred for invasive coronary angiography with coronary computed tomographic angiography (CCTA) and classified lesions as obstructive (≥50% stenosed) or nonobstructive using blinded core laboratory analysis of quantitative coronary angiography. CCTA quantified APCs, including plaque volume (PV), calcified plaque (CP), noncalcified plaque (NCP), low-density NCP (LD-NCP), lesion length, positive remodeling (PR), high-risk plaque (HRP), and percentage of atheroma volume (PAV; PV normalized for vessel volume). The relationship between APCs, stenosis severity, and diabetes status was assessed.

RESULTS

Among the 303 patients, 95 (31.4%) had diabetes. There were 117 lesions in the cohort with diabetes, 58.1% of which were obstructive. Patients with diabetes had greater plaque burden (P = 0.004). Patients with diabetes and nonobstructive disease had greater PV (P = 0.02), PAV (P = 0.02), NCP (P = 0.03), PAV NCP (P = 0.02), diseased vessels (P = 0.03), and maximum stenosis (P = 0.02) than patients without diabetes with nonobstructive disease. APCs were similar between patients with diabetes with nonobstructive disease and patients without diabetes with obstructive disease. Diabetes status did not affect HRP or PR. Patients with diabetes had similar APCs in obstructive and nonobstructive lesions.

CONCLUSIONS

Patients with diabetes and nonobstructive stenosis had an association to similar APCs as patients without diabetes who had obstructive stenosis. Among patients with nonobstructive disease, patients with diabetes had more total PV and NCP.
Circulating small non-coding RNA profiling as potential biomarkers of atherosclerotic plaque composition in Type 1 diabetes
Authors: Giannella Alessandra , Castelblanco Esmeralda , Zambon Carlo Federico , Basso Daniela , Hernandez Marta , Ortega Emilio , Alonso Nuria , Mauricio Didac , Avogaro Angelo , Ceolotto Giulio , Kreutzenberg Saula Vigili de
Published: December 2022

  

OBJECTIVE

Cardiovascular disease (CVD) accounts for most deaths in patients with type 1 diabetes (T1D); however, the determinants of plaque composition are unknown. MicroRNAs (miRNAs) regulate gene expression, participate in the development of atherosclerosis and represent promising CVD biomarkers. This study analyzed the circulating miRNA expression profile in T1D with carotid either calcified (CCP) or fibrous (CFP) plaque. 

RESEARCH DESIGN AND METHODS

Circulating small non-coding RNA were sequenced and quantified using NGS and bioinformatic analysis in an exploratory set of 26 T1D with CCP and in 25 with CFP. Then, in a validation set of 40 CCP, 40 CFP and 24 controls T1D, selected miRNAs expression was measured by digital droplet PCR. Putative gene targets enriched for pathways implicated in atherosclerosis/vascular calcification/diabetes were analyzed. Patient’s main clinical characteristics were also recorded.

RESULTS

miR-503-5p, let-7d-5p, miR-106b-3p, miR-93-5p were significantly up-regulated, while miR-10a-5p downregulated in CCP patients compared to CFP (all FC>±1.5, p<0.05). All candidate miRNAs showed a significant correlation with LDL-cholesterol, direct for the up-regulated and inverse for the downregulated one, in CCP. Many target genes of up-regulated miRNAs in CCP participate in osteogenic differentiation, apoptosis, inflammation, cholesterol metabolism, and extracellular matrix organization.

CONCLUSIONS

These findings characterize miRNAs and their signature in the regulatory network of carotid plaque phenotype, in T1D, providing new insights into plaque pathophysiology, and possibly novel biomarkers of plaque composition.
Two-year follow up from the T1GER study: Continued off-therapy metabolic improvements in children and young adults with new onset T1D treated with golimumab and characterization of responders
Authors: Rigby Mark , Hayes Beverly , Liu Yinglei , Vercruysse Frank , Hedrick Joseph A. , Quattrin Teresa
Published: December 2022

  

OBJECTIVE. The T1GER study showed many metabolic benefits of the TNF-α blocker golimumab in children and young adults with Type 1 diabetes (T1D). Off therapy effects are reported. 

RESEARCH DESIGNS AND METHODS. T1GER was a Phase 2, placebo-controlled randomized trial in which golimumab or placebo was administered for 52 weeks to participants 6-21 years old diagnosed with T1D diagnosed within 100 days. Assessments occurred during the 52-week on-therapy and 52-week off-therapy periods. 

RESULTS. After stopping treatment, C-peptide AUCs remained greater in the treatment versus control group. At Weeks 78 and 104 the golimumab group had lower reductions in 4h C-peptide AUC from baseline where the golimumab groups had reductions of 0.31 and 0.41 nmol/L, while the placebo group had reductions of 0.64 and 0.74 nmol/L. There were also trends in less insulin use, higher peak C-peptide levels and those in partial remission and higher peak C-peptide levels in the golimumab group. Golimumab responders, defined as having an increase or minimal loss of C-peptide AUC and/or being in partial remission at Week 52, showed even greater improvements in most metabolic parameters on and off therapy and had less hypoglycemia during the off-therapy period versus placebo. Adverse events, including infections, were similar between the groups during all time periods of the study.

CONCLUSIONS. In children and young adults with new onset T1D, golimumab preserved endogenous beta cell function and resulted in other favorable metabolic parameters on and off therapy. A subpopulation had disease stabilization while on-therapy with improved metabolic parameters off therapy.
Patient–surgeon sex discordance impacts adverse events but does not affect patient-reported satisfaction after primary total hip arthroplasty: a regional register-based cohort study
Authors: Jolbäck Per , Mukka Sebastian , Wetterling Kristin , Mohaddes Maizar , Garland Anne
Published: December 2022

Background and purpose: The sex of the surgeon has been proposed to be associated with a disparity in clinical outcomes after different surgical procedures. We investigated the association between surgeon–patient sex discordance and adverse events (AEs) and surgical AEs (SAEs) within 90 days after primary total hip arthroplasty (THA). We also investigated patient-reported satisfaction with surgical outcomes 1 year after the surgery.Patients and methods: We conducted a register-based cohort study including primary THAs performed due to osteoarthritis between 2008 and 2016 at 10 publicly managed hospitals in western Sweden. Hospital data was linked to the Swedish Arthroplasty Register and a regional patient register. Logistic regression models investigated discordant sex of patients and surgeons on AEs/SAEs and patient-reported satisfaction with the surgical outcome.Results: 11,993 primary THAs were included in the study. The proportion of AEs for the concordant group was 7.3% and for the discordant group 6.1%. For SAEs, the proportion was 5.0% for the concordant group and 4.3% for the discordant group. After adjustment the discordant group still had a lower likelihood of an AE or SAE than the concordant group: adjusted odds ratio (aOR) for AE (0.82, 95%CI 0.71–0.95) and for SAE (0.86, CI 0.72–0.99). No association was detected between patient-reported satisfaction and sex discordance.Conclusion: Sex discordance between surgeons and patients is linked to a decreased risk of an AE but not a lower level of patient-reported satisfaction with the surgical outcome.
Pengaruh Tingkat Pendidikan, Modal dan Teknologi Terhadap Daya Saing Usaha Mikro, Kecil dan Menengah (UMKM) di Kecamatan Sawan
Authors: Kariyani Ni Nyoman Yuni , Meitriana Made Ary
Published: December 2022

The purpose of this study is to determine (1) the effect of the level of education, capital and technology partially on the competitiveness of micro, small and medium enterprises (MSMEs) in Sawan District, (2) the influence of the level of education, capital and technology simultaneously on business competitiveness. micro, small and medium enterprises (MSMEs) in Sawan District, (3) the magnitude of the influence of the level of education, capital and technology on the competitiveness of micro, small and medium enterprises (MSMEs) in Sawan District. This type of research is causal research with a quantitative approach. The population in this study were all formal MSMEs in Sawan District, Buleleng Regency as many as 2,365 with a sample of 343 respondents who were determined using the Slovin formula. Data collection methods used are interviews and questionnaires. Then, the data analysis technique used is multiple linear regression analysis. The results of this study indicate that (1) there is a partially significant influence between the level of education, and capital on the competitiveness of micro, small and medium enterprises (MSMEs) in Sawan District. Meanwhile, technology does not affect the competitiveness of micro, small and medium enterprises (MSMEs) in Sawan District, (2) there is a simultaneous significant effect between the level of education, capital and technology on the competitiveness of micro, small and medium enterprises (MSMEs) in Sawan District, (3) the magnitude of the influence of the level of education, capital, and technology on the competitiveness of MSMEs is 51.3% while 48.7% is influenced by other variables not tested in this study.
Pelaksanaan Pemungutan Pajak Kendaraan Bermotor Roda Empat Pada Masa Pandemi Covid-19 di UPTD Pelayanan Pajak dan Retribusi Daerah Provinsi Bali di Kabupaten Buleleng
Authors: Pratiwi Dyan , Yuniarta Gede Adi
Published: December 2022

Penelitian ini bertujuan untuk mengetahui bagaimana pelaksanaan pemungutan Pajak Kendaraan Bermotor Roda Empat di masa pandemi Covid-19 yang dilakukan oleh UPTD Pelayanan Pajak dan Retribusi Daerah Provinsi Bali di Kabupaten Buleleng. Jenis penelitian ini adalah penelitian kualitatif, dengan metode pengumpulan datanya adalah studi kepustakan dan penelitian lapangan yang terdiri dari: observasi dan wawancara, serta dokumentasi. Subjek dalam penelitian ini adalah UPTD Pelayanan Pajak dan Retribusi Daerah Provinsi Bali di Kabupaten Buleleng, sedangkan yang menjadi objek dalam penelitian ini adalah pelaksanaan pemungutan pajak kendaraan bermotor roda empat di masa pandemi Covid-19. Hasil penelitian menunjukkan bahwa pelaksanaan membayar pajak sudah berlaku dengan baik dan terlaksana sesuai dengan standar SOP yang berlaku. Begitupun dengan Samsat keliling yang terus beroperasi agar tidak ada masyarakat yang harus terkena denda dengan alasan telat membayar samsat. Walaupun beberapa masyarakat masih harus disadarkan akan kewajiban membayar dalam membayar pajak kendaraan bermotor.
Faktor Penentu Suksesnya Pengajaran Online Pada Masa New Normal
Authors: Martini Ida Ayu Oka , Dimastari Ni Nyoman , Adriati I Gst Ayu Wirati , Sutrisni Ketut Elly
Published: December 2022

Before the pandemic, teaching and learning activities were carried out offline with the guidance of teachers. However, after the Covid-19 pandemic, all teaching and learning activities and extracurricular activities were carried out online. In implementing online learning activities, Pedungan State Elementary School 11 can carry out online learning activities successfully, so it is necessary to study what factors influence the success of online teaching. This research was conducted to find out what factors influence the success of online teaching during the New Normal period at 11 Pedungan State Elementary School. This study uses a qualitative method where this study contains a description of the factors that influence the success of online teaching in the new normal period at 11 Pedungan State Elementary School. Informants in this study were principals, teachers, and parents of students using incidental techniques. The factors that influence the success of online teaching during the new normal period at the 11 Pedungan State Elementary School are as follows: (1) Teacher readiness. Teachers are very ready and have the ability to use information technology. (2) School Readiness. The school has well facilitated this online teaching and learning activity. Such as the internet, computers, laptops, cellphones, special IT rooms. (3) Student Readiness. The students have followed the online learning activities well. according to the schedule determined by the teachers. (4) Readiness of Parents of Students. Parents of students have provided guidance and supervision to their sons and daughters so that online learning can run well.