bluuebunny/crossref_metadata_2025 huggingface dataset:
Marketing turístico e internet: um estudo de caso do site Estrada Real como ferramenta de promoção da rota turística
Authors: Oliveira Emanuelle Aparecida de , Pereira Joyce Kimarce Do Carmo
Published: April 2022

A Internet é hoje um dos principais meios de busca da informação e de promoção do turismo. Entretanto, para que a função de informar seja eficaz, os sites devem ser organizados de modo a instigar no cliente o desejo de consumir o produto ou destino. Desse modo, o presente estudo visou responder se as funções, os serviços e conteúdos disponíveis no site da Estrada Real contribuem para a promoção da Rota por meio da experiência online do consumidor. Para tanto, adotou-se como metodologia a realização de pesquisa qualitativa e descritiva do Portal Estrada Real, com base na adaptação da Listagem de Parâmetros e Critérios para Avaliação da Dimensão da Experiência proposta por Farias (2011) e do Instrumento para a Análise de Websites Turísticos proposto por Bogado e Teles (2003). Os resultados evidenciaram que a promoção turística da Estrada Real é realizada de modo integrado entre o site e outras ações de divulgação e promoção. O portal detém um papel estratégico ao concentrar as informações e orientações que contribuem para despertar o desejo do viajante e contribuir para o planejamento e execução da viagem. Notou-se que através do site é possível minimizar os efeitos relacionados à intangibilidade do produto turístico relacionados à limitação sensorial antes da compra.
A relação entre benefícios, incentivos e custos e a intenção de uso de mídias sociais digitais para o turismo
Authors: Carvalho Mariana Araújo , Ferreira Jorge Brantes , Falcão Roberto Pessoa de Queiroz , De Freitas Angilberto Sabino
Published: April 2022

O artigo propõe estreitar um modelo explicativo com três construtos antecedentes de intenção de uso de mídias sociais: benefícios, custos e incentivos, no contexto brasileiro do turismo on-line. Para tal, foi realizada uma survey com 165 indivíduos e seus resultados analisados por meio de modelagem de equações estruturais, confirmando todas as hipóteses levantadas nesta pesquisa, contrastando com o estudo original no qual se baseou. Foram verificadas relações significativas diretas e positivas entre benefícios e incentivos em relação à intenção de uso de mídias sociais, além de confirmada relação significativa direta e negativa entre custos e intenção de uso de mídias sociais.
Evaluation of indicators of red blood and some indicators of the aggregate state of blood in students in different periods of study, taking into account gender differences
Authors: Maslyakov Vladimir V. , Pavlova Olga N. , Fedotova Natalya N. , Foht Yuliya V. , Akmalov Nizomiddin A.
Published: April 2022

BACKGROUND: An examination session in students can be considered as a manifestation of a stress factor. As a result, during this period there are changes in the basic physiological parameters of students, which are due to the release of a large amount of cortisol. AIM: To evaluate the indicators of red blood and some indicators of the aggregate state of blood in students in different periods of study, taking into account gender differences. MATERIALS AND METHODS: The study design included 100 examined. Of the total number of examined relatively healthy (did not make complaints, were not on the dispensary register and did not have established diagnoses) 100 people (50 men and 50 women). The absence of diseases was confirmed by medical documentation, since all persons of this group underwent an annual preventive examination for admission to study. Included in the study were volunteers aged between 18 and 30 years who, based on medical records, had no acute or chronic illness and gave voluntary consent to participate in the study. The average age was 23 3 years. RESULTS: Based on the presented study, it was found that the stressful situation caused by the examination session leads to pronounced changes in the hemostasis system, which may be a manifestation of endothelial dysfunction, while there are differences between these changes in men and women, which are manifested by differences in indicators of red blood, rheological properties of blood, endothelin levels, von Willebrand factor, tPA-PAI-1 complexes, antithrombin III. In addition, when comparing these indicators by gender, the predominance of fibrinogen levels in female students over men was noted. However, despite the pronounced changes in the hemostasis system, they were not critical and did not lead to the development of pathological conditions, moreover, as further studies showed, these changes were quickly stopped when the stress factor was stopped. As our research shows, after the end of the session, in the period of 7-8 days, both men and women, all analyzed indicators returned to physiologically normal indicators. CONCLUSIONS: Thus, the conducted studies show that during the examination session, which can be regarded as a stressful situation, there is a significant activation of the hemostasis system, while there are certain differences related to gender. Thus, the predominance of fibrinogen levels in female students over men was established.
Pathophysiological and genetic mechanisms of migraine
Authors: Chernov Alexander N. , Galimova Elvira S.
Published: April 2022

Migraine is a heterogeneous neurological disease characterized by the development of periodic attacks of severe throbbing headache and related disorders, which occur in 1115% of the adult population of the planet. The article discusses the main forms of migraine with aura, migraine without aura, hereditary hemiplegic migraine in the context of their main clinical symptoms, molecular genetic risk factors involved in vascular and neurological processes, including activation trigeminovascular system. Emphasis is placed on the role of polymorphisms, hormone genes, neurotransmitters, their receptors, ion imbalance, ion channels, cytokines and growth factors, adhesion molecules, metabolic enzymes, matrix metalloproteases, vascular tone enzymes, antioxidant defense, lipid metabolism, proteins with a not yet established function.
Problems of carsharing integration in urban transport systems of Russian megacities
Authors: Volkova Elena M.
Published: April 2022

Background: Transport problems of Russian megacities are mostly consequences of motorization increasing and inefficient transport policy provided by local transport authorities. At the same time, the structure of urban transport markets is changing because of new business models of transport sharing emerging and development. Different models of sharing could be an important part of urban transport systems, but it requires initiative both of transport companies and local transport authorities.
Aim: to assess the state and determine the prospects for the development of the Russian carsharing market as a whole, as well as its largest segment (the carsharing market in Moscow).
Methods: methods of statistical analysis, graphical representation of information, summary, methods of analysis of industry markets (concentration index, Herfindahl Hirschman index).
Results: In this article barriers for the development of transport sharing in Russian cities are identified, and forms of sharing integration in urban transport cities are developed.
Conclusion: The results obtained can be used by local authorities responsible for public transport services and the development of transport policy in Russian cities, as well as transport organizations engaged in multimodal transportation of passengers in megacities.
Determination of the axial force of a cylindrical linear induction motor with rotational-translational movement of the secondary element
Authors: Solomin Vladimir A. , Solomin Andrej V. , Zamshina Larisa L. , Trubitsina Nadejda A.
Published: April 2022

Background: the variety of modern electric drives requires the creation of new types of electric motors with enhanced functionality. Cylindrical linear induction motors with rotational-translational movement of secondary elements also belong to such electric machines.
Aim: development of a cylindrical linear induction motor with rotational-translational movement of the secondary element.
Materials and methods: the use of a discrete inductor system for the implementation of the rotational-translational movement of the secondary element, the analytical solution of the field problem.
Results: new design of a cylindrical linear induction motor with rotational-translational movement of the secondary element, the ratio for determining the axial force of the motor.
Conclusion: the proposed design of a cylindrical linear induction motor has extended functionality due to the simultaneous implementation of the rotational-translational movement of the secondary element.
Research Insights: Can Voter Preferences Explain Why Governments Underinvest in Public Goods?
Authors: Keefer Philip , Scartascini Carlos , Vlaicu Razvan
Published: April 2022

A new survey of 6,040 voting-age individuals conducted in seven Latin American metropolitan areas reveals that political and interpersonal mistrust, risk aversion and time impatience are strong predictors of voter preferences for public spending. Respondents with higher mistrust or impatience are more likely to choose transfers over public goods; more impatient respondents are also more likely to choose current spending over public investment. Randomized experiments providing information about the benefits of public investment have the expected average demand impacts. Respondents with high political mistrust or impatience increase their demand for public investment significantly less than others.
A novel analysis of Scheimpflug total corneal refractive power following corneal cross-linking in mild to moderate keratoconus
Authors:   Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, Tianjin 300384, China; Hankou Aier Eye Hospital, Wuhan 430000, Hubei Province, China, Pan Chao , Chen Dan ,   Hankou Aier Eye Hospital, Wuhan 430000, Hubei Province, China, Liu Yu ,   Aier School of Ophthalmology, Central South University, Changsha 410083, Hunan Province, China, Wang Hao-Yu ,   Hankou Aier Eye Hospital, Wuhan 430000, Hubei Province, China, Liang Deng-Feng ,   Hankou Aier Eye Hospital, Wuhan 430000, Hubei Province, China, Hua Yan-Jun ,   Department of Ophthalmology, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai 200233, China, Lei Xiao-Hua ,   Hankou Aier Eye Hospital, Wuhan 430000, Hubei Province, China, Zeng Qing-Yan ,   Hankou Aier Eye Hospital, Wuhan 430000, Hubei Province, China, Zhao Shao-Zhen ,   Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, Tianjin 300384, China
Published: April 2022

AIM: To detect an earlier improvement in mild to moderate keratoconus following corneal cross-linking (CXL) with total corneal refractive power (TCRP) using ray tracing method.
METHODS: A total of 40 eyes of 30 consecutive patients who underwent CXL for progressive keratoconus were retrospectively enrolled. The following keratometric parameters provided by Pentacam HR, including maximum keratometry (Kmax), steepest keratometry (Ksteep), 3 mm zonal TCRP centered over corneal apex (TCRPapex,zone 3 mm), zonal mean keratometry and TCRP centered over corneal cone (Kmcone,zone and TCRPcone,zone 1, 2, 3 mm) were evaluated preoperatively and 1, 3, 6, and 12mo postoperatively. Groups 1 and 2 were defined based on Kmax at postoperative 1mo as improved (the initial improvement group) or worsen (the initial deterioration group) compared to the preoperative level.
RESULTS: In the overall group, only keratometric parameters based on ray tracing method displayed significant improvement early at 3mo postoperatively, in which TCRPcone,zone 1 mm and 2 mm exhibited the largest flattening (0.57 D and 0.53 D, respectively). In Group 1, only Kmax, Kmcone,zone 2 mm and TCRPcone,zone 2 mm showed significant improvement initially at 1mo postoperatively, in which Kmax exhibited the largest improvement (1.05 D), followed by TCRPcone,zone 2 mm (0.82 D). In Group 2, only keratometric parameters based on ray tracing method and Kmcone,zone 3 mm showed slight but not significant improvement early at 3mo, in which TCRPcone,zone 3 mm displayed the most improvement (0.19 D), followed by TCRPcone,zone 2 mm (0.15 D).
CONCLUSION: The findings indicate that a 2 mm zonal TCRP centered over Kmax could earlier detect keratometric improvement by CXL compared to other commonly used parameters in mild to moderate keratoconic eyes.
Efficacy evaluation of intravitreal ranibizumab therapy for three types of retinopathy of prematurity
Authors:   Affiliated Eye Hospital of Nanchang University, Nanchang 330000, Jiangxi Province, China, Zou Qiong , Zhang Feng-Jun ,   Affiliated Eye Hospital of Nanchang University, Nanchang 330000, Jiangxi Province, China, Liu Qiu-Ping ,   Affiliated Eye Hospital of Nanchang University, Nanchang 330000, Jiangxi Province, China
Published: April 2022

AIM: To evaluate efficacy of intravitreal ranibizumab (IVR) therapy for aggressive posterior retinopathy of prematurity (ROP), threshold ROP disease and type 1 pre-threshold ROP.
METHODS: A retrospective analysis was performed on 40 patients (76 eyes) who had IVR as the primary treatment for ROP from April 2017 to January 2018. According to disease pathogenic features, the 76 eyes were divided into three groups: aggressive posterior ROP (AP-ROP) group (16 eyes), threshold ROP group (28 eyes) and type 1 pre-threshold ROP group (32 eyes). The characteristics of patients and lesions situation before the first intravitreal injection, and posttreatment fundus outcomes determined by wide-angle RetCam fundus imaging were recorded.
RESULTS: The birth weight and postmenstrual age of first IVR treatment in AP-ROP, threshold ROP, and type 1 pre-threshold ROP groups were significant difference (1087.50±246.78, 1103.75±168.30, 1257.03±210.82 g, P=0.005; 34.50±1.46, 36.89±2.97, 36.50±2.36wk, P=0.008), while the gestational age was not difference (28.00±2.00, 28.54±1.90, 28.59±1.43wk, P=0.510). The retina hemorrhage ratio (with/without: 14/2, 8/20, 5/27), iris neovascularization or vascular engorgement ratio (with/without: 12/4, 11/17, 6/26), and the zone I (inside/outside: 16/0, 2/26, 5/27) in AP-ROP, threshold ROP, and type 1 pre-threshold ROP group were difference significantly (all P<0.05). The regression rates were 37.5%, 92.86%, and 100%, and the recurrence rates were 62.5%, 7.14%, and 0 in AP-ROP, threshold ROP, and type 1 pre-threshold ROP group, respectively (both P<0.05). The recurrence eyes were cured by secondary IVR or retinal laser photocoagulation.
CONCLUSION: IVR is an effective treatment for all types of ROP. The regression of AP-ROP is significantly lower than type 1 pre-threshold and threshold disease. Birth weight, retinal hemorrhage, iris neovascularization or vascular engorgement and lesions located in zone I may be associated with AP-ROP recurrence and retreatment, which should be noted in follow-up.
Factors affecting single-step transepithelial photorefractive keratectomy outcome in the treatment of mild, moderate, and high myopia: a cohort study
Authors:   Department of Ophthalmology, College of Medicine, Qassim University, Qassim, Buraidah 51452, Saudi Arabia, Al-Mohaimeed Mansour M.
Published: April 2022

AIM: To investigate the effect of preoperative factors on visual acuity, higher-order aberrations (HOAs), and index of success for spherical change (S.IOS) after transepithelial photorefractive keratectomy (t-PRK) for treating different grades of myopia.
METHODS: This was a retrospective one-armed cohort study where patients with high, moderate, or mild myopia treated with single-step t-PRK using Amaris 500 Hz excimer laser were evaluated for visual acuity, refractive status, corneal topography, HOAs, S.IOS, and mean efficiency and safety index before and 6mo after surgery.
RESULTS: A total of 154 eyes of 77 patients with mild (n=59), moderate (n=83), and high (n=12) myopia were reviewed. The efficiency and safety indices for vision recovery by single-step t-PRK were 98% and 100%, respectively. The achieved spherical equivalent (SE) was within 1 diopter (D) in 151 (98%) eyes. The median of the S.IOS was 1.18 [interquartile range (IQR) 1.0, 1.4]. The change in S.IOS was significantly correlated with age (P=0.007), 6.5 mm ablation zone (Mann-Whitney U test, P<0.01), and mild and moderate grade of myopia (Kruskal–Wallis test, P<0.001). Trefoil aberration, spherical aberration, and aberration coefficient types of HOA increased significantly (Wilcoxon test, P<0.001) 6mo post-surgery. There was a significant correlation between spherical aberration and aberration coefficient HOAs by myopia grades (P<0.05).
CONCLUSION: Single-step t-PRK has promising short-term outcomes for refractive corrections and vision improvement to treat all three grades of myopia.
Inflammation and dry eye disease—where are we?
Authors:   Darshan Eye Care & Surgical Centre, Chennai, Tamil Nadu 600040, India, Rao Srinivas K , Gokhale Nikhil ,   Gokhale Eye Hospital, Mumbai, Maharashtra 400028, India, Matalia Himanshu ,   Narayana Nethralaya, Electronic City, Bangalore 560001, Karnataka, India, Mehta Paras ,   Sameep Eye Hospital and Corneal Center, Vadodara 390006, Gujarat, India
Published: April 2022

The presence of inflammation in dry eye disease (DED) results in increased patient symptomatology, ocular surface damage and worsening tear dysfunction. It also affects the health of meibomian glands and their secretions which further aggravates ocular surface disease. This article reviews current knowledge regarding ocular surface inflammation in DED and explores the relationships between the vicious cycles of DED, inflammation and meibomian gland dysfunction (MGD). The clinical evaluation of eyes with such changes, markers that identify the presence of inflammation on the ocular surface and current treatment options are discussed.
Direito e pós-modernidade: uma interpretação do filme Submarino Amarelo
Authors: Gordilho Heron José Santana , Pazzini Bianca
Published: April 2022

Este artigo utiliza os métodos histórico-evolutivo e da análise do discurso para investigar o discurso artístico presente na película Submarino Amarelo, lançado pelos Beatles em 1969, para fazer uma crítica ao fictício regime totalitarista implantado pelos Malvados Azuis na cidade Pappeland. O artigo utiliza o filme para fazer um paralelo com os bombardeios sofridos pela Inglaterra durante a Segunda Guerra Mundial. Em seguida, o artigo promove uma crítica ao formalismo jurídico e ao princípio da neutralidade axiológica do Direito, que muitas vezes, pode justificar a omissão dos juízes frente a ilegalidades e desvios de poder praticados por autoridades dos demais poderes. Em seguida, o artigo analisa a cultura jurídica pós-positivista surgida no pós-guerra, que ao se afastar do formalismo jurídico, acaba por promover uma reaproximação do Direito com outros domínios do conhecimento, demonstrando que o ordenamento jurídico não está assentado tão-somente em leis postas, mas também em valores como a dignidade da pessoa humana e a proteção dos vulneráveis.
Extensión sinsedimentaria del Cretácico Inferior en el borde del Bloque Coahuila, un margen tipo rift en México
Authors: Eguiluz y de Antuñano Samuel , Chávez Gabriel
Published: April 2022

Este trabajo presenta datos que caracterizan a un sistema de fallas normales lístricas en dominó, con arreglos sintético y antitético en el borde de lo que se presume es una cuenca tipo rift en el noreste de México. Los afloramientos se localizan dentro de las estructuras anticlinales La Gavia y Arteaga, en el Estado de Coahuila y paleogeográficamente en el borde oriental del Bloque de Coahuila. El análisis de tensores de paleoesfuerzos de estas fallas permite definir un vector de extensión σ3 perpendicular al borde del Bloque de Coahuila, en La Gavia dirigido ~0°/191°-193° y en Arteaga con dirección de σ3 ~0°/200°. Deformación en sedimentos suaves “no litificados” también está presente en la sucesión. El análisis estructural de las fallas y las estructuras sedimentarias en sedimentos suaves sugieren que estas deformaciones fueron sincrónicas al relleno de la cuenca y co-genéticas. Este sistema de fallas se restringe a un nivel estratigráfico específico, por lo que se sugiere que tiene un desarrollo contemporáneo con la sedimentación clástica de la Arcosa Patula y la Formación Carbonera durante el Cretácico Inferior. Se interpreta que la extensión que generó estas fallas y la deformación de sedimentos suave puede ser atribuida a diferentes causas: 1) Como consecuencia de esfuerzos tectónicos regionales durante extensión en un ambiente tipo rift, similar en las cuencas de Sabinas y del Centro de México; 2) A una pendiente acentuada de la cuña sedimentaria entre el Bloque de Coahuila y las cuencas durante rejuvenecimiento del relieve, o bien, 3) La combinación de los mecanismos enunciados.
The Impact of Urban Growth Pattern on Local Road Network: A System Dynamics Study
Authors: Zehawi Raquim Nihad , Hameed Ali Hussein
Published: April 2022

The complex nature of urban growth in cities whose population is exponentially increasing requires a comprehensive understanding to create a precise and descriptive modelling. In order to identify the main factors that influence the behavior of such complex growth and consequently recognize the most applicable future projection to the growth in each urban category, a system dynamics model was developed in which all pertinent variables are incorporated. This model was proven to be capable of simulating the urban growth in Baquba city for some six decades from 1957 to 2017. The simulation results showed very high goodness of fit with the historical records with an R2 ranging between 0.987 and 0.997 proving the validity and applicability of the model. The interaction between various urban categories showed that the road network area was negatively influenced mainly by the rapid growth of residential and public areas. The future projections of this model to the target year of 2035 showed that the residential, public, commercial and industrial categories are increasing by; 55%, 84%, 40%, and 19% respectively. The road area has also increased by 19% in the same projection gaining more expansion than what it got in the last three decades prior to 2017.
TOWARDS A MORE COMPREHENSIVE UNDERSTANDING OF FOSTERING CONNECTIONS: THE TRAUMA-INFORMED FOSTER CARE PROGRAMME: A MIXED METHODS APPROACH WITH DATA INTEGRATION
Authors: Lotty Maria , Bantry-White Eleanor , Dunn-Galvin Audrey
Published: April 2022

Foster carers require high-quality training to support them in caring for children with trauma-related difficulties. This paper describes a mixed methods approach that was applied to evaluate the complex intervention Fostering Connections: The Trauma-Informed Foster Care Programme, a recently developed trauma-informed psychoeducational intervention for foster carers in Ireland. A quantitative outcome evaluation and a qualitative process evaluation were integrated to capture a comprehensive understanding of the effects of this complex intervention. A convergent mixed methods model with data integration was used. Coding matrix methods were employed to integrate data. There was convergence among component studies for: programme acceptability, increased trauma-informed foster caring, improvement in child regulation and peer problems, and the need for ongoing support for foster carers. This research provides support for the intervention suggesting the importance of its implementation in Ireland. The integrative findings are discussed in relation to effects and future implementation.
FAMILY PROFESSIONALS’ ATTITUDES AND STANCE-TAKING ON POST-DIVORCE FATHERHOOD: A QUALITATIVE ATTITUDE APPROACH
Authors: Autonen-Vaaraniemi Leena
Published: April 2022

This article examines divorce professionals’ attitudes and stances in response to common criticisms of how they deal with divorce outcomes for fathers, according to which men are discriminated against in negotiations on the custody and living arrangements of their children. The study applied the relatively new qualitative attitude approach, and hence a further aim was to test its fitness for studying attitudes. Eighteen Finnish family professionals who worked with divorce cases — social workers, psychologists, district court judges, and lawyers — participated in semi-structured interviews in which they discussed claims designed to be provocative. The family professionals were found to show both collective, shared attitudes and diversity in attitudes and stances. The participants strove to position themselves as gender-neutral and as promoters of equality between mothers and fathers, and thus in accordance with the ideal of a good professional. The divorce professionals argued that their overriding aim was to secure the well-being of children. The method revealed some attribution bias, manifested as victim blaming, where fathers themselves were in part held accountable for the gendered post-divorce situation. The results highlight potential areas of cooperation between different types of divorce professionals that could lay a foundation for improving services and support for divorced parents and children.
Asumiendo la vida con una taza de café
Authors: Chávez Achong Julio
Published: April 2022

La caficultura ocupa un lugar significativo en la economía y en la producción agrícola mundial y nacional, pero también en los socioecosistemas donde se localiza, que para el caso de Perú es principalmente la alta Amazonía. Poco se reflexiona sobre la última característica. Este texto no presenta los resultados de una investigación empírica. Pretende ser un ensayo apoyado en enfoques y conceptos de diversas ciencias, resaltando la articulación natural y sociocultural en la actividad cafetalera. Se quiere visibilizar líneas coevolutivas entre la naturaleza y la sociedad humana, que quizá nos predispongan a ser más sensibles y también más responsables con su devenir.
Navigating Linguistic Identities: ESL Teaching Contexts in Quebec
Authors: Riches Caroline , Parks Philippa
Published: April 2022

Linguistic identity is deeply embedded in how individuals identify within groups and cultures (Gee, 2000; Sachs, 2005). The contexts of English as a second language (ESL) teaching in Quebec and ESL teachers’ range of linguistic repertoires provide an interesting landscape for considering issues of identity, equity, and acceptance (De Costa & Norton, 2017; Norton, 2014). Through surveys, interviews and focus groups with pre- and in-service ESL teachers, we explore how language and professional identities develop through the lens of French/English identity intersections and acceptance in these teaching contexts. Our findings show a pattern that is unique to the ESL Quebec context: In French-language schools it is often how an ESL teacher’s linguistic identity is seen, rather than how they selfidentify that appears to be essential to their success in integrating into teaching communities. Our research has important implications for our understanding of the ways ESL teachers’ linguistic identities are performed and accepted within plurilingual contexts of teaching.

« En fait, je suis francophone! . . . Mais ils me voient encore comme anglophone, même si je ne le suis pas du tout. »

L’identité linguistique est profondément ancrée dans la façon dont les personnes s’identifient au sein des groupes et des cultures (Gee, 2000; Sachs, 2005). Les contextes de l’enseignement de l’anglais comme langue seconde (ALS) au Québec et l’éventail du répertoire linguistique des enseignants d’ALS fournissent un paysage intéressant pour envisager les questions d’identité, d’équité et d’acceptation (De Costa et Norton, 2017; Norton, 2014). Par l’entremise de sondages, d’entrevues et de groupes de discussion auprès des enseignants en service et des enseignants en formation d’ALS, nous explorons comment les identités langagières et professionnelles se forment par le prisme des intersections identitaires et de l’acceptation au sein de ces contextes d’enseignement. Nos résultats montrent un schéma qui est unique au contexte de l’ALS au Québec : dans les écoles francophones, il s’agit souvent de la manière dont l’identité linguistique de l’enseignant d’ALS est perçue plutôt que de la façon dont ils s’identifient qui semble être essentielle pour réussir à s’intégrer dans les communautés enseignantes. Notre recherche comporte des implications importantes pour notre compréhension des façons dont les identités linguistiques des enseignants d’ALS sont réalisées et acceptées au sein de contextes d’enseignements plurilingues.
Seis miradas al Tabasco del Siglo XIX
Authors: Castellanos Ramon
Published: April 2022

Los resultados de esta obra no tienen precedentes en la Licenciatura en Historia que se imparte en la UJAT: estudiantes de licenciatura y posgrado se involucraron en un equipo encabezado por in­ vestigadores consolidados y en consolidación, y financiado por nuestra máxima casa de estudios, cada uno de los miembros con su propia propuesta de investigación. Es importante mencionar, que este proyecto obtuvo financiamiento del Programa de Fomento a la Investigación y Consolidación de los Cuerpos Académicos (PFICA). Agradecemos profundamente a la UJAT el haber tenido confianza en este trabajo, y esperamos que la meta de convertir este libro en material de consulta para los interesados en la historia de Tabasco durante el siglo XIX, se logre a corto plazo. Consideramos que aquí están las principales perspectivas desde las cuales se abordó el siglo XIX en Tabasco.
Employed parents' reactions to work-family conflicts: Adaptive strategies of scaling back in Germany
Authors: Adams Ayhan , Golsch Katrin
Published: April 2022

Objective: This study investigates the extent to which employed mothers and fathers scale back on working hours or job pressures in response to work-to-family conflicts (WFC).
Background: Drawing on the concept of adaptive family strategies, it is assumed that WFC is an antecedent to a reduction in work demands. Considering partners’ gender ideology net of other resources and characteristics, we can expect to see gender differences in the adoption of this strategy. Relatively little research has been conducted on associations among WFC, gender ideology, gender, and work-related coping strategies.
Method: We use six waves of the German Family Panel (pairfam, release 11.0), covering the survey years 2012-2019, to examine the effect of WFC and gender ideology on employed mothers’ and fathers’ work-related coping strategies (N=791 mothers and N=1292 fathers). OLS regression is used to estimate the effect of WFC at  and gender ideology  on changes in job pressure and working hours between  and .
Results: Parents who experience WFC are more likely to reduce their job pressure and less likely to scale back on working hours. Gender differences in the reaction between mothers and fathers on WFC only occur in connection with traditional gender ideology.
Conclusion: Scaling back seems not to be a commonly used strategy to react to WFC.
The impact of tourism village on the community’s economy of Setanggor village in Lombok Island, Indonesia
Authors: Putri Tutik Sukmalasari , Mahmud Agus , Aminy Muhammad Muhajir
Published: April 2022

Purpose — To ascertain the development strategy used to establish tourism communities and the economic impact on the community.Research method — This study employs a qualitative approach with interview as the data collection method which is sourced from the head of the tourism awareness group (POKDARWIS) and tourism business actors, including songket artisans, guiders, small traders, breeders, employees of tourist attractions, lodging services, art studios, travel services, compass fertilizer businesses, village heads, and the community.Result — The study's findings include the development model that was used to develop Setanggor Tourism Village, namely the Community Based Tourism development model which entails three components: community participation in decision-making, community involvement in businesses and profit generation, and resource empowerment and profit distribution. The growth of this tourism village has a significant impact on people's income, employment possibilities, prices, community ownership and control, and tourism objects.
Does financial inclusion reduce income inequality in South Sumatra, Indonesia?
Authors: Andaiyani Sri , Adnan Nazeli , Yunisvita  , Riswan Muhammad
Published: April 2022

Purpose — To analyze the impact of financial inclusion toward income distribution inequality in South Sumatra, Indonesia.Research method — The analysis method in this paper is panel regression model. This methodology is used to avoid bias specifications in the model. This paper applied three dimensions of financial which are financial penetration, access to financial services and use of financial services. The data was taken from the Financial Services Authority, Central Bank of Indonesia and the Central Statistics Agency. The data was time series from 2010-2017 and cross section from 9 rural and urban in South Sumatra, Indonesia.Result — The result showed that each district in South Sumatera has divergent degree of financial inclusion index. The degree of financial inclusion index in city area has a relatively higher financial index than hinterland areas. Based on the result of estimations, the impact of financial inclusion index on income inequality is positive and significant. This evidence proved that financial inclusion does not reduce income inequality in South Sumatra, Indonesia.Recommendation — Financial institutions are more motivated to lend to groups like farmers, the impoverished, and small and micro businesses. It is vital for the government to provide more fair financial services amongst regencies and cities.
Synthesis and Activity Test of 1-Allyl-3-(4-tertiary-Butylbenzoyl) Thioureaas a Candidate of an Analgesic Drug
Authors: Razak Rais , Siswandono Siswandono , Ekowati Juni
Published: April 2022

Background: Urea derivatives showed good analgesic activity compared to diclofenac sodium.  The addition of the allyl group to the thiourea and 4-tertiary-butylbenzoyl chlorideis expected to provide a better analgesic effect. Objective: The research aimed to synthesize 1-allyl-3-(4-tertiary-Butylbenzoyl) Thiourea and determine its analgesic activity in mice (Mus musculus). Methods: The synthesis was carried out by a modified Schotten-Baumann reaction, via nucleophilic substitution reaction of allylthiourea on 4-tertiary-butylbenzoyl chloride.  A writhing test was performed to observe analgesic activity in the test compound.  Confirmation of the structure of pure 1-allyl-3-(4-tertiary-Butylbenzoyl) Thiourea was obtained through UV, IR, 1H-NMR, and 13C-NMR data. Results: The compound showed better pain inhibition activity compared to diclofenac sodium, with ED5019,018 mg/kg BW. Conclusion: The compound 1-allyl-3-(4-tertiary-butylbenzoyl) thiourea showed better analgesic activity than diclofenac sodium.
Calcium Decay Ability of Extracts Chromolaena odorata L. Leaves (Asteraceae) on Kidney Stones
Authors: Indriatmoko Dimas Danang , Maulani Maulani , Rudiana Tarso
Published: April 2022

Background: Kidney stones are one of the causes of chronic and acute kidney failure symptoms. The flavonoid compounds in Chromolaena odorata leave extract are thought to dissolve calcium in kidney stones.  Objective: This study aims to determine the activity of Chromolaena odorata leaves extract as a laxative for calcium kidney stones and to characterize the active extract with a liquid chromatograph mass spectrometry. Methods: The leaves of Chromolaena odorata were extracted by ultrasonication method using 3 solvents in stages, namely n-hexane, ethyl acetate, and methanol. The powder for kidney stones was immersed in an extract solution of n-hexane, ethyl acetate, and methanol for 5 hours at 37° C. The reaction results were analyzed for their absorbance using a UV-Vis spectrophotometer. The fraction with the best activity was analyzed for phytochemical content with various typical reagents and LCMS. Results: Methanol extract of Chromolaena odorata has a better effect in dissolving calcium kidney stones. Methanol extract of Chromolaena odorata can reduce calcium in kidney stones with an EC50 value of 16801 µg/mL. Based on phytochemical tests and LCMS analysis, the methanol extract of Chromolaena odorata leaves contains compounds of the tannins, alkaloids, flavonoids, and steroids. Chromatogram at a retention time of 7.76; 8.96; and 10.01 in the methanol extract of Chromolaena odorata identified 3,5,7,4'-tetrahydroxy-8,3'-dimethoxyflavone; 5,7,4’-trihydroxy-3’,5’-dimethoxyflavone, and 5,6,7,8,4'-pentamethoxyflavone compounds. Conclusion: Methanol extract had the best calcium decay activity in kidney stones with an EC50 value of 16801 µg/mL. 3,5,7,4'-tetrahydroxy-8,3'-dimethoxyflavone; 5,7,4’-trihydroxy-3’,5’-dimethoxyflavone, and 5,6,7,8,4'-pentamethoxyflavone compounds are contained in methanol extract which is thought to play a role in shedding calcium in kidney stones.
Acute and Subchronic Toxicity Assessment of 70% Ethanol Extract of Gendarusa Leaves In Vivo
Authors: Kanina Luthfiatu , Solehah Mabluhatus , Plumeriastuti Hani , Widyowati Retno , Wardoyo Bambang Prajogo Eko
Published: April 2022

Background: Justicia gendarussa Burm. f., has been used traditionally in Indonesia for antifertility. Nowadays, a capsule containing 70% ethanol extract of J. gendarussa leaves has been studied for safety. Objective: This study aimed to determine the acute and sub-chronic toxicity of 70% ethanol extract of J. gendarussa leaves in vivo. Methods: In the acute toxicity study, a single dose of 2,000 mg/Kg BW was orally administered to mice (n = 10), which were monitored for 24 days. For the subchronic toxicity study, rats were randomly divided into four groups (n = 10). The control group received distilled water, while the treatment groups received a repeated dose of 40, 200, and 1,000 mg/Kg BW orally for 90 days. Blood samples were collected for hematological and biochemical evaluations. Gross pathology and histopathology of liver and kidneys were assessed. Results: No mortality and non-observed adverse effect level (NOAEL) were observed in the acute toxicity study. The hematological analysis did not show significant differences in the subchronic toxicity study. The SPGT, SGOT, and creatinine values showed no change in groups 2 and 4, but the level of SGPT increased in groups 3. The increasing level of BUN was observed in all treated groups. Abnormalities or histopathological changes were observed in the liver and kidney in groups 3 and 4. Conclusions: Using 70% ethanol extract of J. gendarussa leaves at a therapeutic dose is safer, but it needs attention at a higher dose.
HPLC Method Optimization for Simultaneous Determination of Quercetin, Luteolin, Sinensetin, and Stigmasterol in Herbal Medicines
Authors: Hari Purwani Asih Imulda , Primaharinastiti Riesta , Yuwono Mochammad
Published: April 2022

Background: Quercetin, luteolin, sinensetin and stigmasterol each is the main marker compound in extracts of Sonchus arvensis, Plantago major, Orthosiphon stamineus, and Strobilanthes crispus, respectively. These extracts show nephrolithiasis activity. For quality control of herbal medicines, a high performance liquid chromatography (HPLC) method has been developed in this study using quercetin, luteolin, sinensetin and stigmasterol as phytochemical markers. Objective: to show optimal conditions of analysis and evaluate the stability of quercetin, luteolin, sinensetin and stigmasterol. Methods: The optimal conditions for analysis were carried out by determining the composition of the mobile phase, the flow rate, and the detector's wavelength. Zorbax Eclipse Plus C18 150 x 4.6 mm, 5 μm was used as the column. The stability test was done by analyzing the standard and samples stored at 4oC for 0, 3, 6 and 24 hours. Results: The best separation of the extract was achieved under isocratic conditions using a mixture of water: methanol: phosphoric acid: acetic acid : acetonitrile (50: 30: 0.05: 0.05: 20 v/v/v/ v/v) as mobile phase with detector wavelength of 352 nm, a mobile phase flow rate of 1 mL/min, and a sample injection volume of 10 μL. Conclusion: In this study, the optimal condition for analysis of quercetin, luteolin, sinensetin and stigmasterol. Quercetin, luteolin, sinensetin and stigmasterol were not stable during 6 hours storage, therefore, standard solutions and samples should be made fresh to maintain the stability.
Potential Drug–Drug Interactions in Ambulatory Patients with Hypertension: a Retrospective Study
Authors: Saraswati Marcha Debby , Ardiana Shafira Muti , Suprapti Budi , Assegaf M. Yusuf , Suharjono Suharjono , Hamidah Khusnul Fitri
Published: April 2022

Background: Patients with cardiovascular diseases (CVD) are vulnerable to experiencing drug-drug interactions (DDIs). DDIs are a concern among patients receiving multiple drug regimens but they are also an avoidable cause of adverse drug reactions. The study of potential DDIs (pDDIs) would make it easier for the healthcare provider to deliver better patient care and mitigate pDDIs incidence. Objective: This study aimed to assess the frequency, severity level and risk factors associated with pDDIs among medications used to treat hypertensive ambulatory patients in Universitas Airlangga hospital. Methods: A retrospective observational study was carried out from electronic prescriptions received by hypertensive patients in March 2021. Data collection includes demographic data, the profile of antihypertensive drug use, and pDDIs. pDDIs were identified by severity using Lexicomp Drug Interaction Checker (Application). Univariate logistic regression analysis was used to find associated factors of major pDDIs. A p-value less than 0.05 (≤ 0.05) was considered statistically significant. Results: From 704 patients, 53.98% women and 46.02% men, 89.06% (n = 627) patients had minor to major pDDIs; 1354 pDDIs were identified, 89.4% (n = 1,210) were moderate and 9.8% (n = 133) were major class. Multiple antihypertensive drug regimens had significance associated with the major pDDIs occurrence. Conclusion: We found a high prevalence of pDDIs among hypertensive patients. The majority of pDDIs were of moderate severity. Multiple antihypertensive drug regimens were associated factors in the presence of major pDDIs.
Molecular Docking of Active Compound of Lavandula angustifolia Mill Essential Oil against N-methyl-D-aspartate (NMDA) Receptor
Authors: Lisnasari Baiq Risky Wahyu , Budiatin Aniek Setiya , Ardianto Chrismawan , Khotib Junaidi
Published: April 2022

Background: Lavender oil is widely known to possess a relaxant effect to relieve stress, anxiety, and depression. Linalyl acetate, linalool, geranyl acetate, and β-caryophyllene were the major constituents of lavender oil that potentially act on NMDAR (N-methyl-d-aspartate receptors), and emerging targets in the treatment of depression. Objective: This study aims to predict the binding of lavender compounds to NMDA receptors using an in silico model. Methods: The ligands of the docking study were four major chemical compounds of lavender oil, i.e., linalyl acetate, linalool, geranyl acetate, and β-caryophyllene. 5YE was defined as a native ligand, while memantine, an NMDAR antagonist, was used as a reference ligand. The NMDAR structure was taken from Protein Data Bank (ID 5H8Q), while the lavender compound was sketched in Chem3D. Autodock 4.2 was used to perform the docking analysis. Results: The result showed that beta-caryophyllene had the most potent interaction with NMDAR (free binding energy was -8.02 kcal/mol and inhibitory constant was 1.32 µM). Conclusion: The docking results suggest that beta-caryophyllene could be an NMDAR antagonist and be developed as a treatment for depression.
Unraveling the doping mechanisms in lithium iron phosphate
Authors: Zhang Bo , He Yufang , Gao Hongqiang , Wang Xiaodan , Liu Jinli , Xu Hong , Wang Li , He Xiangming
Published: April 2022

As a result of the extensive research and application of LiFePO4 (LFP) in the past > 20 years, there is now a relatively in-depth understanding of its structural stability, phase transition mechanism and electrochemical properties. However, the difficulties faced by further improving the performance of LFP due to its intrinsic low electronic and ionic conductivity have not yet been effectively solved. In order to unlock the effect of transition metal doping on the physicochemical properties of LFP, we establish doping models for all 3d, 4d and 5d transition metals in LFP and compare and analyze their structural properties, band gaps, formation energies, elastic properties, anisotropies and lithiation/delithiation voltages using ab-initio computational screening. According to our screening results, the V-, Mn-, Ni-, Rh- and Os-doped LFP structures have excellent electrochemical properties and can be used as high-performance cathode materials for Li-ion batteries.
PELOS CAMINHOS DA TOPONÍMIA: O TROPEIRISMO NO PARANÁ DO SÉCULO XVIII E OS LOGRADOUROS DE FORTALEZA EM 1856
Authors: Angelo da Silva Gleilson
Published: April 2022

O estudo da Toponímia pode ser abordado em diferentes contextos e em diversas áreas demonstrando não somente sua versatilidade como a compreensão dos variados fenômenos que ocorrem no tempo e no espaço perpassando por processos e dinâmicas de cunho político, social, econômico, cultural, dentre outros. A origem da nomenclatura de cidades, estradas e vilas, tal como caminhos retoma discussões acerca da forma de nomeação de lugares e traça uma construção histórica, geográfica, antropológica, caracterizando-os de acordo com o momento. Os objetivos norteiam a construção deste artigo, tal como: entender a formação de nomes para os lugares, compreender os fenômenos no tempo e no espaço e relacioná-los com os topônimos, analisar dois contextos em que a toponímia pode ser abordada a partir dos processos observados. A metodologia utilizada permitiu o cruzamento entre os dois contextos e provém de um conjunto de vetores no qual foi utilizado um que possibilitou a abordagem neste artigo. Os dois estudos possuem similaridades no que diz respeito à construção dos topônimos, apesar das unidades léxicas serem diferentes, mas a ideia de denominar um lugar a partir das características que o envolve é nítida, do mesmo jeito que a necessidade de localização aparece claramente nos objetos comparados.
Elastomer-Hydrogel Systems: From Bio-Inspired Interfaces to Medical Applications
Authors: El Fray Miroslawa , Demirci Gokhan , Niedźwiedź Malwina , Kantor-Malujdy Nina
Published: April 2022

Novel advanced biomaterials have recently gained great attention, especially in surgical minimally invasive techniques. Applying sophisticated design and engineering methods, various elastomer-hydrogel systems (EHS) with outstanding performance have been developed in last decades. Those systems composed of elastomers and hydrogels are very attractive due to their high biocompatibility, injectability, controlled porosity and often antimicrobial properties. Moreover, elastomeric properties and bioadhesiveness are making them suitable for soft tissue engineering. Herein, we present the advances in current state-of-the-art design principles and strategies for strong interface formation inspired by nature (bio-inspiration), diverse properties and applications of elastomer-hydrogel systems in different medical fields, in particular, in tissue engineering. Functionalities of those systems, including adhesive properties, injectability, antimicrobial properties and degradability applicable to tissue engineering will be discussed in a context of future efforts towards development of advanced biomaterials.