bluuebunny/crossref_metadata_2025 huggingface dataset:
Xirú e “Abaporu” de Damián Cabrera
Authors: Cota Débora
Published: October 2023

O estudo discute o “comum” (ESPOSITO, 2012; NANCY, 2000) a partir do livro Xirú e do conto “Aboporu” de Damián Cabrera, autor cuja escrita encontra-se pautada nas relações Brasil-Paraguai. Nestas obras estão colocadas em evidência a crise de uma concepção essencialista de comunidade, dada e/ou determinada previamente e o distanciamento do “paradigma moderno imunitário” (ESPOSITO, 2012) que se impõe contra qualquer convivência ou contágio que afete a pretensa pureza da comunidade. Sendo a língua um elemento inerente ao pensamento comunitário, parte-se, também, de certa perspectiva “translingue” (MELLO & ANDRADE, 2019) utilizada pelo autor e que expõe os contatos entre as línguas e as interferências como continuum naturais, transitórios, imprevistos que se articulam nas relações entre estas culturas e não como substâncias dadas previamente.Não menos importante, neste sentido, é a antropofagia manifesta no conto “Abaporu”, uma antropofagia nada ufanista pois, como a perspectiva “translingue” que manifesta Xirú, não é identitária e sim, como têm apontado as leituras contemporâneas que dela fazem Alexandre Nodari (2011), Florencia Garramuño (2019) e Eduardo Sterzi (2017), uma antropofagia como experimentação da diversidade, e com ênfase em uma posição relacional. Desse modo, o “comum” nestas obras se constitui como aquilo que não é próprio à comunidade, como substâncias que se compartilham, mas como laço relacional.
Traduzir o (in)traduzível idioma de Hélène Cixous
Authors: Pimentel Davi Andrade
Published: October 2023

Este artigo apresenta a singularidade do idioma literário da escritora franco-argelina Hélène Cixous a partir da intraduzibilidade de três palavras que estruturam a sua obra, são elas: Ève, Événement e rêve. Ao aceitar a intraduzibilidade do texto cixousiano, o tradutor brasileiro, de modo ético, proporcionará ao leitor de sua tradução um contato mais íntimo com o espaço literário criado por Cixous – um espaço único, em que acontecimentos e sonhos são dados à luz por meio da letra de Ève, mãe-personagem da escritora. Nessa perspectiva, conclui-se, então, que a intraduzibilidade em Cixous não é perda ou fracasso, mas ganho e produção de sentidos.
Relational Database Management Systems in Business and Organization Strategies
Authors: Desamsetti Harshith
Published: October 2023

A collection of interconnected, raw data is a database management system. This collection also includes programs or instructions that may be used to access the data. The enormous collection of data is typically referred to as a Database and contains information necessary to access the data. Providing a method to store and retrieve information held in the database is the management system's primary objective. The database makes it possible to store information more conveniently and efficiently. This article discusses the application used in database management systems and how the data in the application are associated by describing the backdrop of DBMS. This paper also discusses the application that is used in database management systems.
Evaluation of antimicrobial and MMP inhibitory properties of onion peel extracts
Authors: Susila Anand
Published: October 2023

MMP inhibition and antimicrobial properties are important in many applications in the field of Conservative Dentistry and Endodontics to preserve the quality of dentin in a bond or to prevent reinfection and failure in root canal treated teeth. Many natural products are being explored for the above properties as they are safer compared to synthetic ones. Aim: Present study aims to check for the antibacterial action of a small onion and large onion peel extract against Enterococcus faecalis(E. faecalis),Streptococcus mutans(S. mutans) , and also MMP inhibition. Materials and methods: Antibacterial efficacy of small onion and large onion peel extract was evaluated by determining MIC, MBC, and zone of inhibition against E. faecalis, and S. mutans biofilm. UV-visible spectrophotometric analysis was performed for the identification of phytoconstituents present in ethanolic extract of small and large onion peel extract. Computational Drug Designing and Characterization of Phytocompounds present in the extract was determined by Gas Chromatography-Mass Spectrometry (GC- MS) Profiling. Molecular docking (in-silico) was performed using AutoDock open source free software by using editing options and other default parameters. Results: Both Onion peel extracts had good antibacterial properties against both S mutans and E faecalis as determined by their MIC, MBC, and ZOI in this study. They were found to have many phytochemicals notably, β-sitosterol and quercetin. Small onion peel extract had greater quantities of β-sitosterol and quercetin than large onion peel extract. Molecular docking for enzymatic inhibition using in-silico docking study found that both the extracts have MMP2 & 9 inhibition equivalent to control Galardin.
Characterization of Mitochondrial Heat Shock Protein 60 variants in HEK293 Cells Transformed into Steroidogenic
Authors: Arciga Ulalume , Sánchez Sofía , Ménde Sara , Martinez Federico
Published: October 2023

Introduction: During pregnancy, P4 is essential to maintain the maternal-fetal relationship. Maternal cholesterol is the main source of P4 production, a process that takes place in the syncytiotrophoblast mitochondrion. The mechanism and proteins involved in the cholesterol transport for the steroidogenic process are still unknown in detail. The STARD3 protein could be the substitute for its STARD1 equivalent localized in all acute response tissues. However, mutation or null STARD3 mice maintain their reproductive capacity, suggesting other proteins are involved in this process. Previously, we reported that the HSP60 participates in steroidogenesis in mitochondria isolated from the placental syncytiotrophoblast, mitochondrial contact sites or JEG-3. Also, take relevance that non-steroidogenic cells, such as the HEK293, which are human kidney embryo cells, when are transformed into steroidogenic by transfection of the steroidogenic machinery, they synthesize progesterone. To understand better the mechanism through which HSP60 participates in placental steroidogenesis, mutation of cysteine 442, which is essential in the active site for its activity, and deletion of 146 amino acid residues of the N-terminal of HSP60 were performed. The first was implemented to determine whether the protein structure is essential to support steroidogenesis, and the second was done to elucidate whether its activity occurs outside or inside the mitochondrion. Methods: Two mutants were obtained: a) cysteine 442 was replaced by alanine (HSP60C442A) and b) the HSP60-mature (HSP60M) without the mitochondrial-leading sequence. Human kidney cells HEK293 were transformed into steroidogenic by transfection with pECE-P450scc, pCMV-3βHSD-I. The transfected cells were transfected with the HSP60wt, HSP60C442A, or HSP60M plasmids. The transfection was validated by western blot and P4 was determined by an enzyme immunoassay kit. HSP60 without mutations was used as control (HSP60wt). Results: The synthesis of P4 was stimulated by the wild type HSP60 (HSP60wt). However, with both mutants, steroidogenesis occurred as in the control, suggesting that mutants do not support P4 synthesis. Discussion: The mechanism to transport cholesterol to steroidogenic mitochondria requires the full HSP60 to support P4 synthesis, which is necessary to maintain pregnancy. Highlights HSP60 participates in the steroidogenesis of transformed HEK293 cells. Cys442 mutant of HSP60 loses its activity in steroidogenesis. N-terminal deletion of HSP60 is not involved in steroidogenesis. Native HSP60 is critical for steroidogenesis.
It is time we got more personal with advanced therapies- How do we create the right ecosystem for more effective ATMP development in Europe?
Authors: Oldoni E. , Ussi A. , Andreu A. L. , Morrow D.
Published: October 2023

Over the past few years, Advanced Therapy Medicinal Products (ATMPs), especially cell and gene therapies, have brought about a remarkable transformation in the field of therapeutics. ATMPs have the potential to be tailored to individual patients based on their distinct molecular characteristics, making them a crucial aspect of personalized medicine (PM) strategies. Unlocking the full potential of ATMPs is crucial for them to become the treatments of the future. Despite their immense promise, their success is hindered by significant complexity, as evidenced by various systemic bottlenecks in the realms of science, clinical implementation, and regulation. Presently, ATMPs face challenges such as a limited understanding and predictability of in vivo cell fate specific to each patient, regulatory issues caused by rapid technological advancements, inadequate standardization in data acquisition, limited reproducibility during preclinical development, and insufficient knowledge exchange among key stakeholders. Addressing these aspects is essential to fully harness the benefits of ATMPs in healthcare. EATRIS, the European Research Infrastructure for Translational Medicine, is actively enhancing its capabilities in the field of PM through a series of key initiatives. These efforts aim to support also ATMP development and are focused on delivering novel and innovative scientific tools for the scientific community. The final aim is to create the right ecosystem for more effective ATMP development in Europe, by better serving academia and industry in the translation of ATMPs for patient benefit.
Living The Future: Who Can Do What to Improve Human and Environmental Health While Securing Nutritious Food?
Authors: Drangert Jan
Published: October 2023

For the first time in human history, we encounter global limits of essential resources and are being challenged by the consequences of man-made climate change, reduced biodiversity and pollution by chemical substances. Feeding the extra 5.5 billion urban people in this century requires transformation of the present unsustainable agrifood system. Residents can take part in this transformation by changing to healthy diets, recycle food waste and come closer to the food markets, while public and private sectors could look for innovative ways to produce food and to design city infrastructure and buildings that will enhance recycling of limited resouces and reduce environmental foot prints. Global data are forthcoming on resources and on causes of human and environmental ill heatlh, making it possible to conjure future resources restrictions and imbalances of nutrients. Today, the global agrifood system contributes more than a quarter of the global GHG emissions, four-fifth of eutrophication and more than nine-tenth of biodiversity losses. Revised diets, reduced food waste and soilless food production will significantly shrink agricultural land use – and proportionally reduce greenhouse gas emissions and biodiversity losses. Emerging infrastructure and technologies in combination with recycling of nutrients can close the resource gaps by halving the global demand for fertilisers and still feed the world.
Posterior Exposure of the Vertebral Artery in the Subaxial Cervical Spine: A Cadaveric Study
Authors: Mehl Ashley , Rogozinski Zachary , Bauman Megan , Eilertson Carmen , Nourbakhsh Ali
Published: October 2023

Vertebral artery anomalies and anatomic variations noted from cadaveric dissections and imaging studies are well documented within the literature at the craniovertebral junction as well as subaxial cervical spine. Such abnormalities can lead to Vertebral artery injuries causing a myriad of comorbidities for patients. In such situations, Vertebral artery may need to be repaired especially if the dominant artery was injured. In this study, we describe a safe surgical approach to expose the Vertebral artery in the subaxial cervical spine using 6 formalin fixed cadavers to assess the feasibility of our approach. Neural foraminal decompression was performed to identify the nerve roots followed by complete resection of the inferior and superior articular processes at the intended levels. The pedicle was skeletonized, and the posterior wall of the transverse foramen was removed. The Vertebral artery could then be exposed between the two nerve roots. Multiple measurements were reported to guide the approach, including the Vertebral artery diameter between the nerve roots on the left and right side from C3-C7, the distance from midline to the medial edge of the Vertebral artery, and the distance from midline to the lateral edge of the Vertebral artery. To our knowledge, this is the first study describing a safe approach to expose the subaxial Vertebral artery.
Local Production of the Alpha-Emitting Radioi-sotope Actinium 225 with Low Impurities for Targeted Alpha Ther-apy by a Compact Neutron Generator System
Authors: Martellini Maurizio , Leung Ka-Ngo , Gherardi Giuseppe , Falzone Lidia
Published: October 2023

Alpha-particle emitting radioisotope Actinium225 (225Ac) is of great interest for use in Targeted Alpha Therapy (TAT) treatments of e.g., brain tumors, bladder cancer, neuroendocrine tumors and leukemia. A suitable 225 Ac radioligand is also potentially resolutive for the treatment of advanced and metastatic Castration-Resistant Prostate Cancers (mCRPCs). The mCRPC has a mean survival rate of 9-36 months and encompasses a heterogeneous ample range of molecular cancer behavior with a high risk of progression. Global demand for the 225 Ac has spurred several production efforts including extraction from 233U, high energy protons or photon irradiation of 226Ra or spallation of 232Th by, at least, 100 MeV protons. Instead of using accelerators systems such as cyclotrons or LINACs, a Compact Neutron Generator (CNG) system has been developed. A 400kV-10 mA DC (D_7Li) CNG potentially able to produce substantial amount of 225Ac with low 227Ac impurities is here presented. Exploiting the high flux of 10 and 13 MeV energy neutrons generated by the (D_7Li) reactions to bombard a thin target layer of 226Ra, 225Ra/225Ac is produced via the 226Ra(n,2n)225Ra nuclear reaction. By irradiating a 5 mm thick 226Ra layer for 100 hours, about 11-13 mCi of 225Ac can be produced – corresponding to the TAT treatment of about 65 oncological patients – with an estimated 227Ac contamination of about one percent, which is below the acceptable limit for clinical use. This 225Ac production scheme by a suitable CNG should allow to adopt a local/regional approach avoiding the shipment costs of 225Ac. The aim of this paper is to inform the production chain of radioisotopes to be used in medical field and the medical community involved in the application of radiopharmaceuticals for the cure of cancer, that a new technology based on Compact Neutron Generators (CNG) is in a R&D phase and will allow to produce the necessary quantity of radioisotopes for clinical and research purpose. This will be essential in treatment advanced metastatic cancer as for instance the metastatic Castration – Resistant Prostate Cancer.
Comprehensive Analysis of Mortality in a Hospital Center in the Year 2019 to 2020 and the Provision of Palliative Care in Current Medical Practice
Authors: Santos Hector , Martinez Ricardo
Published: October 2023

In this retrospective investigation carried out in a mutual hospital in Montevideo between 2019 and 2020, a quantitative and descriptive analysis of patients older than eighteen years of age who died during that period was carried out. The main objective was to examine the medical records of these patients during the six months prior to their death, using the NecPal 3.1 instrument to assess their clinical variables. The confidentiality and anonymization of the patient data were carefully protected, and a specific database was created for this study. The results obtained provided a detailed description of the patient population, their palliative needs and the quality of care at the end of their lives. The proposed working hypothesis maintained that palliative care did not reduce unnecessary hospital admissions, with a significance level (p) less than 0.05. During the period studied, 200 deaths were registered, with a predominance of women and a mean age of 73.6 years. Of these deceased, 136 had palliative needs, and of these, 50 were admitted to a palliative care unit. The results revealed that patients who did not receive palliative care experienced a greater number of hospital admissions compared to those who did. This led to rejecting the null hypothesis and demonstrating that palliative care had a significant preventive effect in terms of hospital admissions at the end of life.
Different Treatments in Patients with Neuroborreliosis and Coinfections
Authors: Schardt F.W.
Published: October 2023

In case of an acute infection of borreliosis the best therapy is azithromycin 500 mg combined with cotrimoxazole 960 mg, 2x1 per day mostly over 10 days. For chronic and long-lasting infections rifampicin 450mg can be added. Is there also a coinfection with babesia atovaquone combined with tinidazole should be subsequently followed. In a long-lasting stadium of a neuroborreliosis with typical symptoms mostly combined with other bacterial and viral coinfections hydroxychloroquine and/or disulfiram are the best therapy. Whereas disulfiram inhibits P 450-cytochrom, fluconazole induces this elimination system so a combination with artemether is useful. Homeopathic dispensing and plant extractions as well gamma-globulins are surely effective during the chronic or relapse stadium.
Frequency and pattern of congenital heart defects among admitted patient in a tertiary care hospital in Bangladesh
Authors: Munsi M. Abu Sayed , Sayeed M. Abu , Akter Maher
Published: October 2023

Background: Congenital heart disease (CHD) is the commonest of all congenital lesions accounting for nearly 28% of all congenital malformations that have significant impact on morbidity, mortality and heath care cost in children. The aim of study was to determine the pattern of distribution of CHD and the age at which initial diagnosis of CHD was made among children admitted under paediatric cardiology department, Bangladesh Shishu hospital and institute.
Methods: This is a descriptive and prospective hospital-based study conducted in the pediatric cardiology department, Bangladesh Shishu hospital and institute. This study included all the patients admitted during January-June 2022 in pediatric cardiology department having confirmed diagnosis of CHD on basis of echocardiographic report. The collected data was entered and analyzed by using statistical package for social sciences v 24.0.
Results: Out of 337 patient, 175 patient were male (51.9%) and 162 female (48.1%) with male female ratio of 1.08:1. Total 219 cases (64.9%) were acyanotic CHD and 118 (35.1%) were cyanotic congenital heart lesions. In acyanotic CHD ventricular septal defects (VSDs) constitute 38.8% followed by AV canal defect 6.7%, patent ductus arteriosus (PDA) 3.6%. In cyanotic CHD tetralogy of Fallot (TOF) was the commonest lesion accounted for 28 (8.3%) followed by d-transposition of great arteries 16 (4.7%), pulmonary atresia 15 (4.5%), total anomalous pulmonary venous circulation TAPVC 11 (3.3%), tricuspid atresia 9 (2.7%) and DORV, VSD, PS 10 (2.9%). The commonest combination was VSD with ASD in 15 cases (4.5%). Most of the patient was diagnosed in 1st year of age 280 (83.1%)
Conclusions: CHD are very common in our setup and early detection of CHD is increasing. Overall burden of CHD is also increasing therefore a proper population-based study on a large scale is needed to estimate the prevalence accurately.
Study of burn injuries and pattern with seasonal variation in a tertiary care centre
Authors: Verma Kush , Thakurani Sangeeta , Negi Ravikanta , Shah Deepti
Published: October 2023

Background: Burn injuries pose a significant public health concern, necessitating a detailed investigation to enhance injury prevention strategies. This study investigates the distribution and patterns of burn injuries in a tertiary care centre, focusing on gender, age, burn types, outcomes, and seasonal variations.
Methods: Data from a multi-year retrospective analysis (2018-2022) were collected and analysed to determine the gender distribution of burn incidents. Additionally, age distributions were examined to understand the prevalence of burns across different age groups. Burn types were classified into flame, scald, electric, and chemical/miscellaneous, while outcomes were categorised as discharged, abscond/LAMA (left against medical advice), death, or transfer to other departments. The study also investigated the seasonal variations in scald and flame burn incidents.
Results: The highest gender disparities were observed in 2018 and 2019, with 748 and 661 male cases, respectively, compared to 355 and 345 female cases. Children aged 1-10 constituted the largest burn cases, followed by individuals aged 25-40. Flame burns were the most common, accounting for the highest number of cases throughout the study period. Scald burns ranked second, followed by electric and chemical/miscellaneous burns. Most burn incidents resulted in discharge, followed by abscond/LAMA cases. Deaths and transfers to other departments were less frequent outcomes. The number of discharged cases increased gradually over the study period, indicating positive treatment outcomes.
Conclusions: The conclusions emphasize the necessity for all-encompassing preventative initiatives, including public awareness campaigns, safety education, and interventions for vulnerable groups.
Noticias del BID: Vol. 11, No. 10, octubre 1984
Authors:   Banco Interamericano de Desarrollo
Published: October 2023

Noticias del BID, publicación mensual que tiene por objetivo informar acerca de las actividades del Banco Interamericano de Desarrollo.
Aprendamos todos a leer: fascículo 36: toda la familia lee y escribe conmigo
Authors: De Varela Ana Lorena , Martínez Álvarez Silvia
Published: October 2023

Aprendamos Todos a Leer es la iniciativa para la enseñanza de lectura y escritura inicial del BID, donde a través de materiales para el alumno, el maestro y el aula de clase, pretende brindar herramientas para apoyar el proceso de alfabetización inicial. El programa se organiza a partir de una cartelera fonológica presentando para cada fonema (sonido de letra) un personaje caracterizado por un animal. En respuesta al COVID-19, se desarrollaron fascículos para apoyar el trabajo en casa. Este fascículo los niños podrán realizar diferentes actividades para conocer el sonido /s/ cuando se escribe con la letra Z-z. Les ayudaremos a combinarlas con las vocales a, o, u y las consonantes y las consonantes M-m, P-p, N-n, L-l, S-s, F-f, T-t, B-b, D-d, C-c, QU-qu, Y-y, Ll-ll, H-h, Ch-ch, R-r, G-g, J-j.
Aprendamos todos a leer: fascículo 37: toda la familia lee y escribe conmigo
Authors: De Varela Ana Lorena , Martínez Álvarez Silvia
Published: October 2023

Aprendamos Todos a Leer es la iniciativa para la enseñanza de lectura y escritura inicial del BID, donde a través de materiales para el alumno, el maestro y el aula de clase, pretende brindar herramientas para apoyar el proceso de alfabetización inicial. El programa se organiza a partir de una cartelera fonológica presentando para cada fonema (sonido de letra) un personaje caracterizado por un animal. En respuesta al COVID-19, se desarrollaron fascículos para apoyar el trabajo en casa. Este fascículo los niños podrán realizar diferentes actividades para conocer el sonido de la letra -ñ. Les ayudaremos a combinarlas con las vocales y las consonantes y las consonantes M-m, P-p, N-n, L-l, S-s, F-f, T-t, B-b, D-d, C-c, QU-qu, Y-y, Ll-ll, H-h, Ch-ch, R-r, G-g, J-j, Z-z.
Programas públicos de apoyo al capital de riesgo: la experiencia de CORFO en Chile
Authors: Dufeu Claudio , Cortés Javiera , Muñoz Surriba Alexandra
Published: October 2023

El capital de riesgo (venture capital) es una herramienta ampliamente utilizada para promover el desarrollo de ciertas industrias y apoyar el crecimiento de empresas en etapas tempranas que, al no contar con historial financiero, presentan dificultades para acceder a financiamiento. En los últimos 10 años, Chile ha sido uno de los países de LAC que más inversión de riesgo ha recibido, sin embargo, su acceso aún es limitado. Su principal inversor es la Corporación de Fomento de la Producción (CORFO), que en el 2021 comprometió US$955 millones en 60 fondos distintos, apalancando US$339 millones (el 34% del total) desde el sector privado. El presente informe introduce la estructura de este mercado en Chile y analiza, cuantitativa y cualitativamente, los resultados de los programas CORFO de apoyo al capital de riesgo. Cuantitativamente, se desarrollaron dos tipos de análisis: (i) estadística descriptiva, y (ii) análisis de rentabilidad (ROA bruto, ROA neto de los portafolios y ROE neto del fondo de inversión). Cualitativamente, se entrevistaron a 51 actores clave del ecosistema que mostraron un consenso sobre el rol clave de CORFO para el desarrollo de esta industria en el país. No obstante, también señalan la persistencia de barreras que limitan la mejora de las inversiones y el aumento de la escala de los proyectos.
Impact of Foreign Direct Investment From Offshoring on the Efficiency of Russian Companies
Authors:   Financial University Under the Government of Russian Federation, Fedorova Elena A. , Komletsova Varvara G. ,   Moscow Representative Office of Hines International, Inc., Tregubova Mariya K. ,   MegaFon PJSC
Published: October 2023

This paper examines the impact of foreign direct investment (FDI) from offshoring and developed countries on the efficiency of Russian companies. The empirical basis for this analysis includes the financial performance of 18,804 domestic companies from 2013 to 2020, which provided 150,432 data points. The research methodology included panel regression and DEA data shell analysis, which enables comprehensive analysis of a company’s performance in comparison with other companies. Both horizontal and vertical spillover effects were determined in order to trace the effect of offshore companies. Horizontal spillover consists of the side effects on productivity that exclusively national firms are subject to when operating in the same industry alongside firms with foreign investment. Vertical spillover is due to reciprocal and direct links between foreign companies and their suppliers and buyers. This study indicates that efficiency measured in terms of spillover effects is greater for companies with FDI from white offshores than for companies with FDI from gray and black offshores. Furthermore, the efficiency of investment from developed countries in terms of spillover effects is greater than that of investment from gray and black offshores. The spillover effects from investment by gray and black offshores is negligible because of the return of capital. These results may be informative for the top management of Russian enterprises, shareholders, boards of directors, specialists from financial and tax services, analysts, the Ministry of Finance of the Russian Federation, the Federal Tax Service and other interested parties.
Convolutional Neural Networks: A Simple and Functional Approach for COVID-19 Severity Prediction
Authors: Gholami Ali , Yousefi Parastoo , Tabibzadeh Alireza
Published: October 2023

Background and Aims: The Coronavirus disease 2019 (COVID-19) pandemic began in 2020. A major problem during COVID-19 was determining the clinical severity. There are a variety of markers for assessing the COVID-19 severity and outcome. So, this study aims to introduce a new approach for determining the disease severity based on the laboratory data obtained by machine learning algorithms.
Materials and Methods: In this study, we used 100 patients for modeling. We used demographical, background disease, and laboratory data of COVID-19 patients as parameters for training the convolutional neural network model to evaluate disease severity and tried to create a predictive algorithm for future data. The sequential neural network from the Keras library by TensorFlow was used for prediction. The clinical validation of prediction by model was evaluated by the receiver operating characteristic (ROC) curve.
Results: The mean F1 score for our current model was 0.62 (in the range of 0-1). The F1 scores for the severe group and the mild group were 0.8 and 0.45, respectively. The ROC curve for clinical validity revealed an acceptable Area Under Curve (0.085) for both severe and mild categories.
Conclusion: The current study introduces a simple machine learning algorithm as tool for determining COVID-19 severity of by acceptable ROC. This study can lead us to use such algorithms more often in laboratory medicine and clinical decision-making. Furthermore, the present study is just a preliminary study and highlights the need for further research to validate and refine the proposed model.
Sociedad civil y políticas de rendición de cuentas
Authors: Fox Jonathan
Published: October 2023

La influencia de la sociedad civil sobre la rendición de cuentas pública se reconoce ampliamente. Sin embargo, los patrones específicos y los mecanismos causales de su impacto no han sido suficientemente determinados. Este artículo presenta algunas de las elecciones conceptuales explícitas, ineludibles para definir la rendición de cuentas, distinguiendo entre la institucionalmente acotada “rendición de cuentas política” por un lado, y la más amplia y multi–dimensional “política de la rendición de cuentas”, por el otro. Con el propósito de identificar las trayectorias de influencia de la sociedad civil sobre el Estado, este artículo propone desglosar las relaciones de rendición de cuentas entre los actores del Estado y la sociedad civil, abordarlas desde dentro de ellos y, finalmente, evitar un tratamiento aislado como si cada instancia fuera implícitamente monolítica. A la vez, es necesario expandir los marcos conceptuales de la rendición de cuentas, de manera que permitan comprender la interacción entre los ámbitos locales, nacionales e internacionales. La discusión tiene como punto de partida la diferenciación entre las dimensiones vertical y horizontal de la rendición de cuentas, y enfatiza la interdependencia e interacciónque se da entre ellas.
Impacto macroeconômico em empreendimentos nascentes: Análise com os Microempreendedores Individuais brasileiros
Authors: Rocha Bernardo Almeida , Rocha Luiz Célio Souza , Novais Ana Liriel Rodrigues , Pelogio Emanuelly Alves
Published: October 2023

A formalização das empresas é vital para a estabilidade dos novos negócios e empregos formais no Brasil. Nesse contexto, objetivou-se analisar a influência da situação macroeconômica do Brasil na abertura e fechamento de Microempreendedores Individuais (MEIs). Para alcançar esse propósito, investigamos as correlações entre os dados de abertura e fechamento de MEIs, o Produto Interno Bruto (PIB) e a taxa de desocupação no país. A metodologia adotada classifica-se como aplicada, explicativa e quantitativa. Os dados foram analisados utilizando a correlação de Pearson, aplicado através do Teste t, bem como a regressão simples, com o uso do Teste F-ANOVA, todos a um nível de significância de 5%. Os resultados evidenciaram uma forte correlação positiva entre a abertura de MEIs e a taxa de desocupação, enquanto a correlação com o PIB foi negativa, moderada e estatisticamente não significativa. Não foi observada uma correlação estatisticamente significativa entre o fechamento de MEIs e os fatores macroeconômicos analisados. Portanto, conclui-se que a taxa de desocupação desempenha um papel importante na quantidade de MEIs abertos (apresentando uma relação diretamente proporcional), enquanto o PIB do país tem menos impacto na abertura de MEIs (apresentando uma relação inversamente proporcional).
Mądrość. Psychologia mądrych myśli, słów i czynów
Authors: Sternberg Robert J. , Glück Judith
Published: October 2023

Tłumaczenie publikacji czołowego badacza inteligencji, twórczości i mądrości, Roberta J. Sternberga z Uniwersytetu Cornella w USA oraz austriackiej badaczki z Uniwersytetu w Klagenfurcie, Judith Glück. Czytelnicy, szukający mądrych odpowiedzi na trudne pytania, znajdą tu pełen zestaw zagadnień związanych z mądrością: od uzasadnienia, dlaczego w dzisiejszych trudnych czasach ta tematyka jest ważna, poprzez przegląd głównych podejść teoretycznych, aż po postulaty jak rozwijać kompetencje mądrościowe, a także jak je rozpoznawać i kultywować u siebie. Lekturą z pewnością zainteresują się nie tylko badacze zdolności poznawczych i mądrości, profesjonalni psychologowie i pedagodzy oraz studenci tych kierunków, filozofowie i edukatorzy, ale także wszyscy, którzy pragną wieść mądre życie. Prezentujemy dzieło, jakiego jeszcze w polskiej psychologii i pedagogice nie było; dzieło, które uzupełnia dotkliwą lukę w badaniach nad tym jednym z najważniejszych i najcenniejszych przymiotów ludzkiego życia, jakim jest mądrość. Prof. dr hab. Krzysztof J. Szmidt Publikacja wpisuje się w dyskusję dotyczącą kształtu i sensu edukacji we współczesnym świecie, kompetencji kluczowych i możliwości przygotowania młodych ludzi na wyzwania jutra. Napisana jest w sposób zachęcający do polemiki i głębokiej refleksji – nie pozostawia czytelnika neutralnym. Dr Tomasz Knopik
A Method of Constructing p-rep Designs
Authors: Vinaykumar L.N. , Varghese Cini , Jaggi Seema , Varghese Eldho , Harun Mohd , Karmakar Sayantani , Kumar Devendra
Published: October 2023

Background: Early generation breeding trials (EGBTs) are very important in plant breeding programmes. In most cases, a large number of breeding lines are to be tested, often with very few available resources and it is also required to repeat these trials in a number of environments. For such trials, an alternative is to use partially replicated designs, where a proportion of the test lines are replicated at each environment. Methods: Here, a general method of constructing a series of efficient partially replicated designs for EGBTs in equal block sizes, through initial blocks is developed. Result: Taking all environments together, the designs obtained are equi-replicate and are partially balanced. They are cost effective in terms of resources as they require lesser replications.
Temporal Assessment of Crop Protection Agents in Water Bodies of Haryana Districts
Authors: Mishra S. , Singh M.K. , Saini M.K. , Alam S. , Thakur L.K. , Mukherjee I. , Kumar J.
Published: October 2023

Background: The study was conducted to quantify the presence of crop protection agents in 233 water samples collected from water bodies situated in cities of Panipat, Karnal, Rohtak, Sonipat and Hisar districts of Haryana, India. Water samples were collected during different seasons the year for the period from 2014-2018. Methods: The samples were processed by liquid- liquid partitioning method and quantified by Gas Chromatography and Mass Spectrometry. The water samples were screened for 55 pesticides. Result: Estimation of the residues revealed that 23.5 and 6.6% of pesticides were detected in 68 and 165 monsoon and winter samples, respectively. Chlorpyrifos, pretilachlor, butachlor and lambda cyhalothrin were predominantly present in all the water samples analyzed. Chorpyrifos detected in water samples from Karnal were above standard limit prescribed by EPA 8081and8141 but some samples were below UAS Health advisory life time value.
Economics of Rubber Plantation in Mokokchung District
Authors: Longkumer Watisenla , Sharma Amod
Published: October 2023

Background: The present study was conducted with an aim to study the socio-economic and livelihood of the rubber growers in Mokokchung district, further main objective is to provide extra income as well as generating more employment through rubber plantation. Methods: For the present research study a total of 160 respondents were selected from 8 villages, out of which, 94 respondents (58.75 per cent) were small, 50 respondents (31.25 per cent) were marginal and 16 respondents (8.00 per cent) were medium farms, respectively. Result: Gross income for marginal, small and medium farmers was ₹ 2,48,400, ₹ 6,21,000 and ₹ 9,93,600 and net income was ₹ 95,300, ₹ 4,10,797.88 and ₹ 7,46,600. About 52.50 per cent respondents were employed in government sector with an average annual income of ₹ 1,01,70,021, followed by 38.75 per cent respondents with an average annual income of ₹ 31,00,016, 5 per cent respondents were daily wage earners with an average annual income of ₹ 2,10,002 and 3.75 per cent respondents were working in private sectors with an annual income of ₹ 5,40,000. Maximum required trained labourers and hired labourers, 89.00 per cent had permanent workers and 29.00 per cent had contract labourers. Total two marketing channels were involved viz; channel I: Producer-Processor, channel II: Producer-Agent-Processor. In channel I, the marketing cost incurred by the producer was ₹ 38/kg and the marketing cost incurred by the agent was ₹ 27/kg. In channel II the marketinpg cost incurred by the producer was ₹ 3/kg and the marketing cost incurred by the agent was ₹ 36/kg. The major cconstraints were lack of local trained labourers, lack of government funding, lack of market, price instability, lack of training programmes and road condition.
Cognitive Training and Rehabilitation in Aging
Authors: KARLI Hakan , CAN Handan
Published: October 2023

Aging is a life stage in which progressive deterioration occurs in biological, psychological, and socio-cultural processes. Therefore, along with all the other changes observed in aging, cognitive change is inevitable. In older adulthood, the speed of processing information, the ability to remember contextual information such as where and when events occur, and executive function performance are impaired. Moreover, this change in cognitive processes causes the deterioration of functionality in daily life. Although it is well known that physical activity, nutrition, and social support play a key role in preventing the adverse effects of aging, the impact of cognitive training and rehabilitation have been relatively less studied. This review aims to examine cognitive training and rehabilitation practices applied to different cognitive processes (episodic memory, working memory, executive functions, attention and processing speed) to help compensate for or regain cognitive functions that are impaired in older adults. In this context, the effectiveness of the practices, the transfer of gains to different cognitive areas, and whether they are preserved for long periods were examined. The contribution of conscious and systematic practices, such as cognitive training and rehabilitation, in reducing the adverse effects of aging has been discussed.
A Study on Mao Zedong's Cursive Style
Authors:   The Korean Society of Calligraphy, Qin Yu
Published: October 2023

Mao Zedong was a famous calligrapher in modern times. Because of his unique style, his calligraphy lived alone in the calligraphy world. Later generations were called Mao Style.Especially known for cursive writing, the spirit of superiority, still into the holy territory, by the world praise, admiration.Mao Zedong's cursive calligraphy has a wide range of methods, and its origin can be traced directly to the Eastern Han Dynasty cursive calligraphy.Because of the complexity of the learning experience and the wide range of methods, Mao Zedong's cursive style is studied in stages to reveal his choice of cursive script and to better explain his “inheritance” and “innovation”.
Aesthetic Consideration of Hyangpa Lee Juhong’s Calligraphy and Painting
Authors:   The Korean Society of Calligraphy, Seol Kyeong-hee
Published: October 2023

Lee Juhong(1906-1987) was a writer, educator, and artist, born in Hapcheon, Gyeongsangnam-do, and worked in Busan. This paper is a study of his calligraphy, poetry, and painting. He experienced various hardships during his life of 80 years, including Japanese rule and the Korean War. Therefore, he expressed human agony and the fundamental essence of his difficult life through various genres of art, including literature. He led students to culture and art during his entire life as a professor of the Department of Korean Language and Literature at the National Fisheries University of Busan, integrated by Pukyong National University in Busan afterward. In addition, he was a comprehensive artist who engaged in artistic activities in a variety of genres, including poetry, novels, essays, plays, and criticism, as well as children's poems, fairy tales, juvenile fiction, calligraphy and painting, folk paintings, comics, book designing and binding, and theater directing. He also wrote collections of literary works and translations that amount to about 300 volumes.
I analyzed and examined Hyangpa Lee Juhong’s calligraphy and painting by classifying them into literary communication aesthetics of calligraphy and painting and authentic East Asian aesthetics of calligraphy. The simple beauty, humorous beauty, and natural beauty abstracted from the literary communication aesthetics of calligraphy and painting help the aesthetic emotions organically linked in Hyangpa’s poetry, painting, and calligraphy to communicate through the integrated empathy of creation and appreciation. Therefore, I confirmed that simple, humorous, and nature-friendly works become communication aesthetics that heals complex minds.
I summarized the authentic East Asian aesthetics of calligraphy into five beauties.: The first is the simple and gentle beauty that looks smiling. The second is the beauty that to have and to lack generate each other, and the third is the beauty that expresses a neat yet majestic aura with flowing strokes. The next is the beauty that is plain but not sick of, and the last is the magnanimous beauty while remaining faithful to nature without restraint. He used diverse genres of literature and various fields of art. He attempted many experimental things in calligraphy, so we could evaluate that he created a new style and method of calligraphy. In addition, the humanistic, literary, and aesthetic sentiments accompanying Confucius's humanism and Zhuangzi's vital freedom at the bottom of Hyangpa art formed his view of literature, art, and life. Thus, they elaborately emerged in Hyangpa’s calligraphy and painting.
Fungicide resistance risk assessment
Authors:   ADAS Boxworth, UK, Grimmer Michael
Published: October 2023

New fungicide active substances are at risk of losing efficacy due to the development of resistance in target pathogen populations. In the European Union, an assessment of resistance risk is required by regulatory authorities for the approval of each fungicide product This chapter will review the development and scientific rationale of the widely used risk matrix approach to fungicide resistance risk assessment. This type of approach relies on previous experience of resistance with a particular fungicide mode of action, pathogen and agronomic system to assess the level of risk. A more recent trait-based approach that doesn’t rely on prior knowledge will also be reviewed. Finally, this chapter will consider future trends in fungicide resistance risk assessment.
Quinone outside inhibitor fungicide resistance: selection patterns and the current situation
Authors:   Syngenta Crop Protection AG, Switzerland, Torriani Stefano F. F. , Sierotzki Helge ,   Syngenta Crop Protection AG, Switzerland
Published: October 2023

This chapter focuses on Qol fungicide resistance, specifically drawing attention to selection patterns and the current situation of Qol resistance. The chapter begins by describing the history of resistance and resistance mechanisms, then goes on to provide three case studies to describe different Qol resistance evolutionary patterns and dynamics. Current global sensitivity to Qol groups 11, 11A and 45 is also discussed.
Ecologia intertextual, imagens rurais e metapoesia nas "Heroides", de Ovídio
Authors: Avellar Júlia Batista Castilho de
Published: October 2023

As Heroides, de Ovídio, foram frequentemente interpretadas em termos de mescla de gêneros, conferindo-se especial destaque para a mistura dos gêneros epistolar e elegíaco, com a incorporação também de elementos da retórica. Este trabalho analisa passagens da obra em que são explorados temas, vocabulário e imagens rurais, a fim de investigar a presença nas cartas das heroínas de elementos característicos da poesia didática antiga. Assim, com base nas relações entre natureza e literatura, investigo nas quinze primeiras epístolas das Heroides a ocorrência de símiles, metáforas e descrições envolvendo o ambiente e as atividades rurais (como a agricultura, a caça e a criação de animais). Com isso, busco discutir as significações que tais imagens rurais conferem à obra e colocar em realce os diálogos possíveis com a tradição didática antiga, especialmente com as Geórgicas, de Virgílio.
Structural Relationship between Nail Artists’ Growth Mindset, Burnout, and Job Performance
Authors: Lee Hyunjeong , Kwon Ki Han
Published: October 2023

Purpose: This study aimed to determine ways for improving the service quality of beauty service providers by understanding the structural relationship between the growth mindset, burnout, and job performance of nail artists.Methods: The sample groups comprised 194 adult men and women working as nail shop operators or nail artists in Seoul and Gyeonggi provinces, and data were collected via an online web-based survey over 15 days from January 1 to 15, 2023. Path analysis was conducted using SPSS 28.0 and AMOS 28.0 according to the structural equation model for the collected data.Results: First, in the growth mindset of nail artists, the intelligent mindset was found to have a significantly negative (−) effect on burnout and a significantly positive (+) effect on job performance. Second, the personality mindset had no significant effect on either burnout or job performance. Finally, burnout had a significantly negative (−) effect on the job performance of nail artists.Conclusion: Educational institutions must provide support to improve the intelligent mindset of nail artists. Further follow-up studies are necessary to enhance the quality of service from the perspective of service providers.
Rethinking the Role of Estrogen and the Effect of Aromatherapy on Hot Flashes in Menopausal Middle-aged Women
Authors: Sim Junghwa , Kwon Ki Han
Published: October 2023

The purpose of this review is to systematically evaluate the effectiveness of aromatherapy as a complementary and alternative medicine (CAM) for hot flashes (HF) in menopausal middle-aged women. This review is a literature review, and a descriptive review method was used in this study. A total of 436 references were selected using representative journal search sites such as PubMed, Google Scholar, Scopus, and RISS, and among them, a total of 44 papers were selected in the final stage based on the years 2000-2022 using PRISMA flow diagram. Aromatherapy has been shown to relieve HF in menopausal middle-aged women. Aromatherapy, which is simple, non-invasive, and safe to use, requires various systematic studies such as effective CAM for hot flashes, types of aroma oils, usage methods, and dosages.
A Study on the Singling and Technology of Sang-go Cut Style by Beauty Experts
Authors: Jang Seon-Mi , Jung Won-Ji
Published: October 2023

Purpose: This study aims to provide baseline data on men's cut styles by investigating and analyzing the perceptions, technical, and the height of the singling in the Sang-go cutstyles for hairdressers working in the field.Method: The survey was conducted for the hairdressers and the SPSS 25.0 statistical program was used for data analysis. Frequency analysis, factor analysis, and Cronbach's α coefficient were calculated, and crossover analysis, independent sample t-test, one-way ANOVA, and Duncan test were performed.Result: Following the analysis of the reliability in the perception of singling, the design effect was shown to be the highest, followed by necessity, then satisfaction. The technical was found to be "the connection of the singling and the top," and after analyzing the determinants of the singling height, "the shape of the head" was found to be the highest.Conclusion: Through the study, the importance of singling in the Sang-go cut style was found out, and basic data necessary for men's cut design was established through a study on singles and techniques for the archaic cut style of beauty experts.