bluuebunny/crossref_metadata_2025 huggingface dataset:
IOT BASED INTELLIGENT GAS LEAKAGE DETECTION SYSTEM
Authors: Robin Edwin P
Published: May 2022

Safety has always been an important criterion while designing home, buildings, industries as well as cities. The increased concentration of certain gases in the atmosphere can prove to be extremely dangerous. These gases might be flammable at certain temperature and humidity conditions, toxic after exceeding the specified concentrations limits or even a contributing factor in the air pollution of an area leading to problems such as smog and reduced visibility which can in turn cause severe accidents and also have adverse effect on the health of people. Many accidents occur in day to day life like explosion because of LPG (Liquid Petroleum Gas) leakage. Major harm is caused, if gas leakage is not detected early. But now the system can detect the gas leakage using gas sensor (MQ5). In this LPG gas leakage detector, device will get connected to WIFI, the minimum and maximum parameter can be set accordingly. Such IoT as well as Arduino based gas leakage detector systems can be installed in homes, hotels LPG gas storage areas. . Key Words: LPG, MQ5, IoT, Arduino
Pneumatic Vulcanizing Machine for Tyres
Authors: Shah Bharat
Published: May 2022

In the modern world, tyres have become an important part of our daily routine. Whether be it buses, cars or two-wheelers, they have a very vital role in moving vehicles. And tyres are available in wide range of shapes and sizes – as per the requirements and applications of each and every vehicle. For different terrains, different types of rubber tyres are used of different composition, and with that, comes different types of problems which needs new and advanced solutions.
IoT based Smart Shoe for Visually Impaired
Authors: Sandeep Mr.M.Sai
Published: May 2022

IoT based Smart shoe system for visually impaired is a system made with the help of ultrasonic sensors, GPS and GSM module paired to an Arduino UNO board. Internet of things is all about making physical objects communicate with other objects or even with humans. Sightless people face great difficulty to travel independently. They must depend on others in many aspects of their life. The Major problem is when they walk on the road. With a stick in hand, they cannot detect every obstacle that comes in their way. The Smart shoe design provides a long-term solution for the blind to walk on roads independently. The smart shoe will help the Blind person to reach his destination independently. It is built using IoT Technology in which the shoe will be embedded with various sensors, Microcontroller, and buzzers. The shoe warns the user by making noise with the buzzer when he/she walks in front of an obstacle. The smart shoe communicates and coordinate with each other to ensure that the user does not collide with any obstacle in his way. Visually Impaired People face issues while travelling outdoors, this paper presents a literary review of overcoming such issues by making wearable sensors by planting them on shoes using IOT (Internet of Things). Use of ultrasonic sensors and buzzer to notify the end-user regarding upcoming obstacles. Keywords: Arduino UNO, IOT, Sensors, Buzzer, GPS and GSM module.
Guía de aplicación de diseño de experiencias para la escenificación de la identidad de la Época Colonial.
Authors: Campaña Alarcón Mariela Elizabeth
Published: May 2022

El presente trabajo tiene como finalidad el estudio de los rasgos característicos de la Época Colonial desde su implantación iniciada con la conquista española de los territorios latinoamericanos, el auge de una sociedad colonial implantada a los nativos y la redefinición del estatus político y administrativo del Ecuador que conllevó a la independencia y el inicio de la República. Ahora bien, a todo lo mencionado se añade el estudio del usuario donde se evidenciará las necesidades de la persona involucrándola en el contexto desde una perspectiva interna y externa de la vida cotidiana colonial basada en el reflejo de la investigación obtenida de la combinación de disciplinas como la psicología, la antropología, el arte y la producción audiovisual que representan el empleo de medios de índole multifacéticos. Principalmente, la investigación busca vincular el diseño de experiencias con la Época Colonial a través del reconocimiento de recursos obtenidos de esta metodología de diseño para aplicarlos en la revitalización de un espacio en desuso que escenificará la identidad de este periodo histórico. Al proponer una Guía de aplicación de diseño de experiencias para la escenificación de la identidad de la Época Colonial.
Reviewer Acknowledgements for Global Journal of Health Science, Vol. 14, No. 5
Authors: Grey Erica
Published: May 2022

Reviewer Acknowledgements for Global Journal of Health Science, Vol. 14, No. 5, 2022.
Exploring the Experiences and Coping Strategies of Divorcees and their Children in Asogli State of the Volta Region
Authors: Dogbey Alice Emmanuella  , Amos Amuribadek Adangabe  , Florence Kazi
Published: May 2022

The study was conducted to explore the lived experiences of divorcees, children of divorce, and the coping strategies they employed in dealing with their situations. This is a qualitative study that adopted descriptive phenomenological approach. A total of 20 respondents comprising 14 divorced women and men, 6 children of divorcee were used in the study and sampled through snowball and purposive sampling techniques. Data was gathered using semi-structured interview, and focused group discussion guides. The study revealed that the divorcees experienced physical, mental, social and financial problems. Children of the divorcee significantly experienced stress, emotional pains, sorrow, and worry about their condition.  Again, the study revealed that divorcees and children of divorcee faced many consequences, they were not aware of availability of counselling services that could help them.  It was recommended, among others, that divorcees who are mostly single parents must be given marital counselling and/or post-traumatic stress management.  Again, the establishment of community-based counselling centres in the Asogli state for this purpose would be laudable.  Finally, the District Assembly, traditional rulers in the Asogli state, Civil Society Organisations, and government agencies should offer care and support services to divorcees and their children including scholarships to children from divorced homes.
Pengembangan Konsep Formulasi Dokumen Perencanaan Pengadaan Barang/Jasa Pemerintah
Authors: Rakhman Agus Arif
Published: May 2022

Keberhasilan proses pengadaan barang/jasa pemerintah yang mengutamakan value for money sangat ditentukan oleh manajemen perencanaan pengadaan barang/jasa yang sistematis, akuntatabel, dan dapat dievaluasi secara berkala. Jurnal ini menggabungkan kebijakan penguatan kualitas perencanaan pengadaan barang/jasa dan prosedur perencanaan pengadaan barang/jasa yang diatur pada Peraturan LKPP Nomor 11 Tahun 2021 tentang Pedoman Perencanaan Pengadaan Barang/Jasa Pemerintah. Kebijakan terkait identifikasi kebutuhan, konsolidasi, penyusunan spesifikasi teknis dan perkiraan harga, identifikasi pengadaan, analisis pasar masih dianggap terpecah-pecah apabila diimplementasikan ke dalam suatu dokumentasi, sampai dengan proses akhir berupa pengumuman rencana umum pengadaan sehingga diperlukan suatu formulasi dokumen dari sisi implementasi untuk menggambungkan berbagai kebijakan pada perencanaan pengadaan melalui suatu formulasi dokumen. Metode penelitian yang digunakan adalah deskriptif kualitatif dengan mengolah berbagai peraturan pemerintah terkait pengadaan barang/jasa. Penelitian ini menghasilkan sebuah konsep formulasi dokumen perencanaan pengadaan barang/jasa pemerintah sejak pengisian formulir identifikasi kebutuhan, proses identifikasi pengadaan, prosedur konsolidasi pengadaan, yang kemudian dilanjutkan dengan formulasi analisis pasar untuk kemudian dituangkan pada dokumen kertas kerja spesifikasi teknis/kerangka acuan kerja serta perkiraan harga yang menjadi data dukung dokumen perencanaan pengadaan dan perencanaan anggaran. Kemudian formulasi dokumen dilanjutkan dengan menggambungkan reviu perencanaan anggaran dan perencanaan pengadaan oleh Aparat Pengawas Internal Pemerintah (APIP) sebelum keseluruhan dokumentasi dituangkan ke dalam dokumen anggaran untuk kemudian melakukan pengumuman pada Rencana Umum Pengadaan. Jurnal ini merupakan seri-ke1 dari keseluruhan 9 jurnal pada “Seri Jurnal Perencanaan Pengadaan Barang/Jasa” yang dapat dijadikan referensi akademis untuk instrument penelitian terkait perencanaan pengadaan barang/jasa oleh para pelaku pengadaan ataupun akaemisi di bidang pengadaan barang/jasa.
Negosiasi Harga e-Purchasing Katalog Dalam Pengadaan Barang/Jasa Pemerintah
Authors: Kristianto Ade
Published: May 2022

Negosiasi harga adalah salah satu metode dalam pelaksanaan e-Purchasing Katalog mencapai tujuan pengadaan untuk mendapatkan barang/jasa yang efesien dan efektif. Peran Pelaku Pengadaan (Pejabat Pengadaan/Pejabat Pembuat Komitmen) dalam melakukan negosiasi harga sangat penting sekali, karena harga barang yang tercantum di Katalog adalah harga yang ditetapkan oleh Penyedia Katalog. Pemerintah telah mengatur secara rinci dan tegas ketentuan-ketentuan dalam melakukan negosiasi harga pada e-Purchasing Katalog. Namun secara praktik, sulit dilaksanakan karena terbatasnya informasi mengenai strategi dan etika pengelola pengadaan barang/jasa dalam melakukan negosiasi harga sehingga perlu dikembangkan tata cara penerapan strategi dan etika dalam melaksanakan negosiasi harga e-Purchasing Katalog. Penelitian ini menggunakan metode deskriptif kualitatif dengan mengolah berbagai peraturan pemerintah terkait pengadaan barang/jasa dan juga studi pustaka lainnya yang mendukung. Penelitian ini diharapkan menjadi pendekatan ilmiah praktis bagi pelaku pengadaan untuk melaksanakan negosiasi harga pada e-Purchasing Katalog mulai dari persiapan pengadaan dan pelaksanaan e-Purchasing Katalog di aplikasi e-Purchasing Katalog LKPP.
Potensi Partisipasi Usaha Mikro dan Kecil pada Bela Pengadaan dan Simpel Kemdikbudristek dalam Rangka Pemulihan Ekonomi Nasional
Authors: Septian Eka
Published: May 2022

Tulisan ini tentang peran sentral yang dimiliki Usaha Mikro dan Kecil (UMK). Perspektif yang digunakan dengan metode deskriptif kualitatif, metode ini merupakan tipe penelitian yang bukan bermaksud untuk menguji hipotesis tertentu, tetapi hanya menggambarkan apa adanya mengenai suatu keadaan tertentu, dengan teknik pengumpulan data dengan studi literatur  dari regulasi mapun jurnal terkait dan survei data sekunder bersumber dari Kementerian Koperasi & UMKM dan juga dari Lembaga Kebijakan Pengadaan Barang/Jasa Pemerintah. Dari studi literatur dan survey data yang telah dilakukan, dapat dinyatakan bahwa UMK sebagai penggerak roda perekonomian Indonesia karena fleksibelitas yang tinggi dalam aktivitasnya, menurut data pada tahun 2019, secara kuantitas pangsa pasar didominasi oleh UMK dengan persentase 99,89%, dibandingkan segmentasi usaha menengah dan besar yang hanya 0,11%. UMK menjadi penyumbang dalam menciptakan lapangan pekerjaan sekaligus mengurangi pengangguran dan menciptakan nilai tambah dalam Produk Domestik Bruto (PDB). Implikasi dari pandemi covid-19 mengakibatkan masalah perekonomian Indonesia, khususnya pelaku UMK yang mengalami penurunan penjualan dan peningkatan pengangguran disebabkan daya beli masyarakat yang turun. Berkenaan dengan hal tersebut, afirmasi peran pemerintah dalam memberikan peluang lebih besar kepada produk lokal dan UMK dengan mengalokasi lebih banyak paket pengadaan, sebanyak 37.113 paket untuk belanja di lingkungan Kemdikbudristek atau dengan nilai  pagu Rp 7.844.209.829.149 menjadi potensi partisipasi dari UMK. Partisipasi UMK pada pengadaan barang/jasa pemerintah di lingkungan Kemdikbudristek melalui Bela Pengadaan dan Simpel ditengah kondisi daya beli masyrakat yang turun, adalah dalam rangka pemulihan ekonomi nasional
Mencari Kesetaraan Dari Penyetaraan Jabatan Administrasi Pengelolaan Barang Milik Negara Menjadi Pengelola Pengadaan Barang/Jasa
Authors: Darmawan Sastyo Aji
Published: May 2022

Perampingan birokrasi melalui penyederhanaan struktur organisasi baik pemerintah pusat maupun daerah, adalah salah satu point yang disampaikan oleh Presiden Joko Widodo setelah dilantik menjadi presiden untuk kedua kalinya. Presiden Joko Widodo mengungkapkan rencananya untuk penyederhanaan birokrasi melalui pemangkasan jumlah tingkatan eselon PNS. Kementerian Hukum dan Hak Asasi Manusia (Kemenkumham) melakukan penyederhanaan birokrasi kepada 738 pejabat strukturalnya untuk dialihkan ke jabatan fungsional. Dalam Keputusan Menteri Hukum dan Hak Asasi Manusia Nomor M.HH-82.KP.03.04 Tahun 2021 tanggal 31 Desember 2021 tentang Pemberhentian dari Jabatan Administrasi dan Pengangkatan dalam Jabatan Fungsional Melalui Mekanisme Penyetaraan di Lingkungan Kemenkumham juga tercantum angka kredit beserta tambahan tugasnya. Ihwal Penyetaraan Jabatan ini sudah disosialisasikan jauh hari sebelum Keputusan tersebut diterbitkan. Namun masih saja banyak Pejabat Administrasi di Biro Pengelolaan BMN Kemenkumham yang seolah-olah masih tidak tahu harus bagaimana menyikapinya. Mereka menyampaikan keresahannya tentang bagaimana dapat mendulang angka kredit di jabatan barunya, Pengelola Pengadaan Barang/Jasa, padahal mereka belum memiliki kompetensi tentang pengadaan barang/jasa dan bahkan belum pernah mengikuti sertifikasi ahli pengadaan tingkat dasar/ahli pengadaan level 1. Kekhawatiran ini seolah-olah diperburuk dengan kondisi bahwa rutinitas yang dilakukan oleh para Pejabat Administrasi di lingkungan Biro Pengelolaan BMN sebelum adanya Penyetaraan Jabatan sudah sesak dengan tugas-tugas Pengelolaan BMN.
Application of artificial intelligence in respiratory medicine
Authors: Zhang Chunxi , Wu Weijin , Yang Jia , Sun Jiayuan
Published: May 2022

In recent years, thanks to the dawn of big data, the substantial improvement in computing power, and breakthroughs in algorithm research, artificial intelligence has developed rapidly, and remarkable progress has also been made in its application in medicine. In the field of respiratory medicine, the auxiliary diagnosis of lung cancer is currently the topic on which medical artificial intelligence is the most studied. Therefore, this paper mainly focuses on the diagnosis procedure of lung cancer, and comprehensively summarizes the application of artificial intelligence in the segmentation and detection of pulmonary nodules, classification of benign/malignant pulmonary nodules and intrathoracic lymph nodes, classification of lung cancer pathological images, and lung cancer prognosis analysis. In addition, the application of artificial intelligence in other respiratory diseases such as COVID-19, pneumothorax and pleural effusion is briefly introduced. In summary, artificial intelligence is widely used in the auxiliary diagnosis of respiratory diseases, and has a great potential to become a valuable assistant to respiratory physicians in the near future.
LEGALITAS HADIS MUTAWATIR DALAM PERSPEKTIF IMAM JALALUDDIN AS-SUYUTI
Authors: Qomaruzzaman Qomaruzzaman
Published: May 2022

Ulama hadis  berbeda pendapat dalam memberikan pengertian dan menentukan karakter pada hadis mutawatir. Perbedaan tersebut berada pada pemberian definisi dan legalitas hadis.  Penelitian ini membahas kriteria hadis mutawatir menurut perspektif Imam Suyuti. Penulis juga akan membahas tentang legalitas hadis mutawatir dalam pandangan Imam Suyuti. Dengan menggunakan telaah pustaka pada kitab Qatfu al-Azhar al-Mutanasirah fi al-Akhbar al-Mutawatirah penulis menyimpulkan dua hal. Pertama, berbeda dengan ulama hadis lainnya, Imam Suyuti tidak mensyaratkan adanya minimal jumlah perawi pada setiap tingkatan (sahabat, tabi’in, dst) dalam hadis mutawatir. Kedua, Imam Suyuti tidak meragukan keberadaan hadis mutawatir dengan syarat-syarat yang ia tulis dalam kitabnya, Qatfu al-Azhar.
Detection of Breath Alcohol After Oral Anti-Inflammatory Spray Use
Authors: İŞLER Yeşim , KAYA Halil , YÜKSEL Melih , AY Mehmet Oğuzhan , BULUT Mehtap
Published: May 2022

Background: We aimed to investigate the effect of ethanol-containing oral antiseptic sprays on breath alcohol levels and its relationship with time and body mass index.
Materials and Methods: This study includes the results of 99 patients. Body mass index of each individual was recorded. Individuals were asked to blow into the alcoholmeter immediately after taking 8 puffs of oral antiseptic sprays and in this way, the breath alcohol concentration. 0th minute value was obtained. The measurements were repeated three times, at the 3rd, 5th, and 10th minutes. Breath alcohol concentration values were recorded.
Results: The median age of the patients was 34 (IQR 25-75: 28-42) and 55 (55.6%) of the patients were male. While the mean alcohol level measured at the 0th minute was 0.075 ± 0.013 promil, the mean alcohol level measured at the 10th minute was 0.001 ± 0.004 promil. A statistically significant difference was found between the alcohol levels measured at the 0th, 3rd, 5th, and 10th minutes (χ²:288,762, p<0.001). A statistically significant difference was found between all groups in the pairwise comparison of alcohol levels measured at the 0th, 3rd, 5th, and 10th minutes (p<0.001).
Conclusion: This study shows that ethanol-containing sprays may exceed the legal criteria in breath alcohol measurements.
Pulmonary Embolism and COVID-19
Authors: ÖZDEMİR Serdar , ÖZKAN Abuzer
Published: May 2022

We have read the research titled “Analysis of Patients with Pulmonary Thromboembolism Who Received Thrombolytic Therapy in The Emergency Department” prepared by Emektar et al. with great interest. We thank the authors and the editorial board for publishing this successful and informative paper contains data of patients presented on pre-pandemic period. The patient profile has also changed with the spread of SARS-CoV-2 worldwide. We also would like to mention a few important points about mechanism of pulmonary embolism in SARS-CoV-2 infection.
A Rare Heart Valve Involvement in Adult Polycystic Kidney Disease: A Case Report
Authors: DUYAN Murat , GÜNLÜ Serhat , SARIDAŞ Ali , CANDER Basar , SOLAÇ Yıldızhan
Published: May 2022

In adult polycystic kidney patients, heart involvement is frequently observed in the progressing process of the disease, as well as the pathologies created in various other organs. Among others, left ventricular hypertrophy and mitral valve prolapse are generally observed. A 42-year-old female patient, receiving dialysis due to chronic renal failure resulting from autosomal dominant polycystic kidney disease, was admitted to the cardiology outpatient clinic with complaints of high blood pressure, dyspnea and abdominal pain. During clinical examinations, a cyst was detected in the tricuspid valve on echocardiography. In this case study, we aimed to present a patient with a cyst on the tricuspid valve, which has not been previously encountered in adult polycystic kidney patients.
Effect of Denture Cleansers on Surface Roughness and Flexural Strength of Heat Polymerised Acrylic Resin – Invitro Study
Authors: G Sandhya , MM Prem Kumar , P Manimaran , C Dhinesh kumar , D Sai Sadan , M Abirami
Published: May 2022

The surface roughness of denture base fabricated with Acrylic resin is crucial in the maintenance of denture hygiene. Rough surfaces are found to accumulate microorganisms which can colonise the microirregularities leading to foul smell and also compromise the health of the oral tissues. This Study was aimed to measure the surface roughness and flexural strength of heat polymerised resin of 180 day use after its immersion in denture cleanser. Two types of heat polymerised acrylic resins Acryln – H and DPI were selected. 40 specimens were prepared out of each resins. Amoung 40 specimens 20 specimens are taken as a control from each of the resins. Then the specimens were immersed in distilled water and in denture cleansing tablet sodium perborate monohydrate. Surface roughness (RA) and flexural strength (S) was measured before and after immersion in denture cleanser solution.The surface roughness were increased in both Acryln-H and DPI heat cure acylic resin materials after immersion in denture cleansers. The flexural strength were much reduced in Acryln-H material on comparing with DPI after immersion in denture cleanser.
The page as monument: epigraphical transposition in the runica manuscripta tradition of early Medieval England
Authors: Birkett Tom
Published: May 2022

Most surviving runic inscriptions from early medieval England were produced in an ecclesiastical context, and the influence of manuscript writing practices on the runic tradition can clearly be discerned. The manuscript record of runes or runica manuscripta that flourished particularly in the context of Anglo-Saxon missionary activity to the Continent has, however, usually been regarded as a late antiquarian development, largely detached from the epigraphical tradition. In this paper, I argue that not only did manuscript practice clearly influence epigraphy, but also that several uses of runes in manuscripts can be considered as extensions of the epigraphical tradition. Some runica manuscripta also seem to evoke pointedly the monumental tradition, including associations with permanence, public display, and memorialisation. Through the case studies of decorative uses of runes, scribal signatures, and textual interventions in runes, I argue that there is a relatively consistent association between the runic script and monumental epigraphy that can be transposed onto the manuscript page for particular effects, which rely on received knowledge of the epigraphical tradition long after the use of runes in monumental contexts had ended.
Manuscripts and monuments: the ten contracts of Djefai-Hapi and economies of knowledge
Authors: Kahl Jochem
Published: May 2022

Reconfigured and recontextualized several times, the ten contracts inscribed on the walls of the monumental tomb of the regional governor Djefai-Hapi I at Asyut (c. 1920 BC) are a particularly striking example of how different material and different contexts generate new meaning. Originally written on papyrus or leather, the ten contracts between Djefai-Hapi and the priests of the main deities of his city and the necropolis staff ensured that Djefai-Hapi would be able to participate in the local cult(s) on a regular basis after his death. Put in a new context, the 'tomb edition' of the ten contracts went beyond Djefai-Hapi's insistence on later successors honouring his agreements. It exercised a powerful effect on Djefai-Hapi's deification in a dynamic interplay of monumental tomb-architecture, high-quality statues, elegant language used in the tomb-inscriptions, and Asyut's local cults. After more than two millennia, the contracts were stored in a temple more than 200km away from Asyut and did not have legal meaning any more. Instead, they had changed to a commemorative text written on papyrus. Defining and reconstructing actors, institutions, materials, and working processes provides insight into the colourful history of knowledge transfer in Ancient Egypt.
Wireless Vibration Monitoring System for Milling Process
Authors: Fikri Muhamad Rausyan , Saptaji Kushendarsyah , Azmi Fijai Naja
Published: May 2022

The implementation of industrial revolution 4.0 in manufacturing industries is necessary to adapt to the rapid changes of technologies. The milling process is one of the common manufacturing processes applied in the industries to produce engineering products. The vibration that occurs in the milling process can disturb the continuity of the process. The wired vibration monitoring system implemented in the manufacturing process needs to be replaced with the wireless monitoring system. Hence wireless vibration monitoring system is developed to solve the problem with wired monitoring systems where tucked cable and high cost are the main challenges of the wired monitoring system. The wireless monitoring system setup is built using three components: sensor node, monitoring node, and base station. Milling experiments with various depths of cut, feed rate, and spindle speed were conducted to examine the performance of the wireless monitoring system. The results indicate the wireless system shows similar data recorded by the wired system. The wireless vibration monitoring system can identify the effect of milling parameters such as depth of cut, feed rate, and spindle speed on the vibrations level. The effect of cut depth is more significant than spindle speed and feed rate in the defined parameters.
Genetic parameters of milk and lactation curve traits of dairy cattle from research farms in Thailand
Authors: Pangmao Santi , Thomson Peter C. , Khatkar Mehar S.
Published: May 2022

Objective: This study was aimed to estimate the genetic parameters, including genetic and phenotypic correlations, of milk yield, lactation curve traits and milk composition of Thai dairy cattle from three government research farms.Methods: The data of 25,789 test-day milk yield and milk composition records of 1,468 cattle from lactation 1 to 3 of Holstein Friesian (HF) and crossbred HF dairy cattle calved between 1990 and 2015 from three government research farms in Thailand were analysed. 305-day milk yield was estimated by the Wood model and a test interval method. The Wood model was used for estimating cumulative 305-day milk yield, peak milk yield, days to peak milk yield and persistency. Genetic parameters were estimated using linear mixed models with herd, breed group, year and season of calving as fixed effects, and animals linked to a pedigree as random effects, together with a residual error. Univariate models were used to estimate variance components, heritability, estimated breeding values (EBVs) and repeatability of each trait, while pairwise bivariate models were used to estimate covariance components and correlations between traits in the same lactation and in the same trait across lactations.Results: The heritability of 305-day milk yield, peak milk yield and protein percentage have moderate to high estimates ranging from 0.19 to 0.45 while days to peak milk yield, persistency and fat percentage have low heritability ranging from 0.08 to 0.14 in lactation 1 cows. Further, heritability of most traits considered was higher in lactation 1 compared with lactations 2 and 3. For cows in lactation 1, high genetic correlations were found between 305-day milk yield and peak milk yield (0.86±0.07) and days to peak milk yield and persistency (0.99±0.02) while estimates of genetic correlations between the remaining traits were imprecise due to the high standard errors. The genetic correlations within the traits across lactation were high. There was no consistent trend of EBVs for most traits in the first lactation over the study period.Conclusion: Both the Wood model and test interval method can be used for milk yield estimates in these herds. However, the Wood model has advantages over the test interval method as it can be fitted using fewer test-day records and the estimated model parameters can be used to derive estimates of other lactation curve parameters. Milk yield, peak milk yield and protein percentage can be improved by a selection and mating program while days to peak milk yield, persistency and fat percentage can be improved by including into a selection index.
Selective and Simple Determination of Isoquinoline Alkaloids in Papaver Species by Ion Mobility Spectrometry
Authors: Tajabadi Fateme , Khalighi-Sigaroodi Farahnaz , Ghorbani Nahooji Majid , Ghiaci-Yekta Mona , Ghasemi Seyed Vahid
Published: May 2022

: In this study, a fast and precise method for determining three opium alkaloids (morphine, codeine, and thebaine) in different parts of some Papaver species was developed and validated with a low limit of detection (LOD) of 0.05 - 0.20 mg/L. The proposed method was based on three extraction steps by alkaline aqueous solution/chloroform/acidic aqueous solution and analysis by ion mobility spectrometry (IMS) and high-performance liquid chromatography (HPLC). After optimizing IMS parameters based on an experimental design, IMS was applied to analyze the extracts of seeds, stems, leaves, and capsules of seven Papaver species collected from different regions of Iran. All prepared samples were analyzed by HPLC and IMS at the same time. Then, the obtained results of the two instrumental methods were compared. The HPLC did not detect morphine in the prepared samples, while IMS results showed trace amounts of morphine in the capsules and leaves of four Papaver species. Other results were comparable and showed that IMS is more sensitive, affordable, and faster than HPLC for alkaloid analysis.
Location of the Optic Foramen Relative to the Sphenoid Sinus and Orbital Apex Structures
Authors: Cinaroglu Selim , Zor Kursad Ramazan , Guresci Kursat , Keles Hacı
Published: May 2022

Background: Orbital decompression is performed to reduce intraorbital pressure by removing the fat tissue and bone around the orbit. Access to proper equipment, experienced personnel, and adequate anatomical knowledge are essential to perform this procedure. To achieve maximum decompression, surgeons need to open the orbit up to the apex, including the optic foramen and the annulus of Zinn. Objectives: This study aimed to determine the location of the sphenoid sinus relative to the optic foramen using computed tomography (CT) scan, which is essential for orbital decompression surgery, in the Central Anatolia Region, Turkey. Patients and Methods: This cross-sectional study was conducted on 64 patients from the Turkish population between March 15 and April 15, 2021 in the Central Anatolia Region. The patients were selected using the purposive sampling method. Based on the cranial CT scans, a total of 128 orbits were evaluated using the hospital’s picture archiving and communication system. Patients included in this study were admitted to the hospital with headache. However, their CT images, evaluated by an experienced radiologist, were reported to be normal. The relationship between the optic foramen and the anterior surface of the sphenoid sinus was examined, and the location of the optic foramen was determined as anterior, posterior, or equal to the sphenoid sinus. Descriptive statistics were measured for statistical analysis. Results: The participants of this study included 32 men and 32 women in the age range of 20 - 67 years. Based on the analyses, the optic foramen was mainly opposite to the anterior aspect of the sphenoid sinus in both females and males; this finding was more prominent in females. In the right orbit, the mean distance of the optic foramen to the anterior surface of the sphenoid sinus was +6.97 mm if the optic foramen was anterior to the anterior surface of the sphenoid sinus, while it was -4.1 mm if the optic foramen was located posteriorly to the anterior surface of the sphenoid sinus. Similarly, in the left orbit, the mean distance of the optic foramen to the anterior surface of the sphenoid sinus was +6.97 mm if the optic foramen was located anteriorly, while it was -4.15 mm if the optic foramen was located posteriorly to the anterior surface of the sphenoid sinus. The position of the optic foramen was symmetrical in 60.9% of cases in the two orbits. Conclusion: Based on the results of CT scan, the optic foramen was mainly located opposite to the anterior aspect of the sphenoid sinus; this finding was more frequently observed in females (59.4%) than in males (40.6%). The present results can provide further information for surgeons to perform orbital decompression or surgeries posterior to the orbit.
How Can Faculty Members Produce More Articles?
Authors: Mehranfard Shahzad , Pelarak Ferdos , Kousari Raana , Kalani Leila
Published: May 2022

Background: An important challenge for universities and research managers is to motivate faculty members to carry out research and increase the number of articles, which increases the university’s research ranking. The first stage in organizing research in the community is the achievement of a correct understanding of the capabilities and available facilities and realizing the weaknesses and strengths of research programs. Objectives: This study was conducted to investigate the barriers to research from the perspective of the faculty members of Dezful University of Medical Sciences, Khuzestan, Iran. Methods: This descriptive-analytical cross-sectional study was performed to determine the barriers to research from the perspective of the faculty members of Dezful University of Medical Sciences. The data collection tool was a questionnaire consisting of two personal information sections and a questionnaire containing 39 items in four domains. The SPSS software (version 21), independent t-test, and analysis of variance were used to analyze the data. Results: The mean age of the participants was 26.9 ± 7.43 years. Additionally, 25 (50%) and 25 (50%) subjects were male and female. Moreover, 34 (68%), 13 (23%), and 3 (6%) participants were working in the Medical School, Nursing School, and Paramedical School, respectively. Conclusions: From the perspective of the faculty members, there were several barriers to research activities, the most important of which was related to the individual domain and financial support for the researcher. Furthermore, the specification of the research process by eliminating cumbersome administrative rules and creating a balance between obligatory hours dedicated to research and education can be an effective stage in the process of performing research activities.
Ireland Reimagined
Authors: Elements  , Sepe Czar
Published: May 2022

Ireland's decade of centenaries (2012-2022) commemorates historial milestones that led to the country's independence from Great Britain and the creation of the Republic of Ireland. However, since the advent of the Irish nation, its history has always been a contested space - where opposing political social, and cultural groups negotiate between historical narratives - to lay claim to a 'true' Irish history. This paper presents the competing historiographies involved in the Irish government's decade of centenaries and identifies the socio-political agenda behind state commemorations. A historical analysis of the commemorations that took place in the 2010s proves that socio-political considerations factored in the way Ireland's founding was portrayed by the Government, the public, and civil society. Overall, this paper concluded that the Irish Government's chief aims were to strike a conciliatory tone with northern Ireland, 'crowd-out' opposing historical narratives, and project Ireland's economic progress through the irish proclamation. Neverthless, academic historians and the public intervened in this negotiation to create reimagined histories of Ireland.
Food for Thought
Authors: Elements  , Cohen Caroline
Published: May 2022

This paper describes the connection between the foods we eat and our brain health. It asses the effects of certain nutrient groups on th ebrain and their role in the pathogenesis of Alzheimer's Disease (AD), specifically the brain abnormalities associated with it, including Tau Tangles, Amyloid-Beta Plaques, and oxidative stress. The intake of a high fat diet, with saturated fats in particular, has been shown to aggravate Beta-Amyloid Protein accumulation and the formation of Tau Tangles, whereas a diet low in saturated fat and high in N-3 fatty acids has been shown to reduce Amyloid-Beta Plaque formation and lessen cognitive decline. An antioxidant-ruch diet improves learning and memory in mice and combats the heightened oxidative dress found in AD brains. The mind and bash diets have both been shown to diminish Alzheimer's incidences, but the mind diet proves itself to be more impactful than the dash due to its specific emphasis on the consumption of foods high in antioxidants.
The Continuing Containment
Authors: Elements  , Fu Daniel
Published: May 2022

There exists a shifting balance of power in east asia. China, the rising power, is attempting to dismantle american hegemony in the indo-pacific. To counter growing chinese capabilities, the Trump administation has adopted a policy of active containment, escalating U.S.-China tensions. This paper will explore China's rise from the perspective of Great Power Politics, establish there is a power transition, and lastly, argue that the Trump's administation containment strategy has been fundamentally counter-productive to American interests in the region and unsuccessful at moderating Chinese behavior. Lessons can be drawn from the Trump adminitation's misteps that can be used to formulate more effective zchina policy under the Biden administration.
Wrestling with Giants
Authors: Elements  , Riordan Luc
Published: May 2022

It is unquestionable that the companies that hold the public eye today are mostly from the technology sector. Growing rapidly from the 1990s and onwards, the current leaders in the field now see themselves at the center of concerns over monopoly and trust forming issues that have led to renewed interest form the US Attorney General's Office. Trust busting has been a staple of American Competition Law, particularly in the past few decades and focus is not being turned on the social media giants that have become key players in everyday life. This paper looks to analyze the reasons for such action and the concerns surrounding litigation of this type with particular reference to current complaints against Google, Facebook and Microsoft. While showing the benefits of action to protect legitimate competition, the paper seeks to caution against the notion of overlitigation and the perverse incentives it may provide. Finally, it offers some alternatives to the standard trust-busting solution of company breakups to account for the advent of the digital afe in which these tech giants exist.
The Demon of the Belfry
Authors: Elements  , Stebbins Sean
Published: May 2022

The Penny Press' sensational coverage of the 1895 Emmanuel Church Murders (committed by San Francisco Medical zstudent Theofore Durrant) highlighted their obsession with deviant sexuality and gruesome violence. Contemporary newspapers continually cited Durrant's lack of romantic success, highlighted his peculiar medical background, speculated about his intimate relationship with his mother, and emphasized the maidenhood of his two young female victims - all while engaging in what scholar Karen Haltunnen terms the 'Pornography of Violence'. Scholars have not sufficiently studied how newspapers and other media during this time romanticized traditional sexual relationships while simultaneously fetishizing violence - especially if that violence was sexual in nature. This paper will argue that rapidly changing conceptions of sexual normativity during the Gilded Age - and the conflict between representatives on both sides of that fierce debate - manifested themselves in the implicity, and often these explicity sexualized coverage of Durrant.
In-vitro Activity of Tigecycline versus Daptomycin against Clinical Isolates of Enterococcus Species
Authors: Rajan Reena
Published: May 2022

Introduction: Tigecycline is a potential therapeutic agent for multidrug resistant gram positive and gram negative organisms. The clinical efficacy of synergic combination of daptomycin with betalactam antibiotics have been described against various species of Enterococcus isolates. Aim: To detect the in-vitro activity of tigecycline and daptomycin against Enterococcus species and their antimicrobial activity with Vitek 2 automated system. Materials and Methods: This was a cross-sectional study conducted at Department of Microbiology, Vinayaka Mission’s Kirupananda Variyar (VMKV) Medical College and Hospitals, Salem, Tamil Nadu, India. Isolates of Enterococcus obtained over a period of two years from March 2016 - March 2018 from various clinical samples were identified by standard biochemical method and their antimicrobial susceptibility pattern was determined. Minimum Inhibitory Concentration (MIC) of tigecycline and daptomycin was determined by Vitek 2 automated system. Analysis of data was done by using frequency distribution and percentage. Results: Out of 211 Enterococcus isolates studied, 23 (10.90%) isolates showed decreased susceptibility to daptomycin with MIC of ≥8 µg/mL. All isolates showed 100% susceptibility to tigecycline. Conclusion: The present study showed potent antimicrobial activity of tigecycline against various species of Enterococcus. Decreased susceptibility to daptomycin has been observed among the study isolates. Further clinical investigations are required to know the potential benefits of these agents in therapy.
A native promoter–gene fusion created by CRISPR/Cas9‐mediated genomic deletion offers a transgene‐free method to drive oil accumulation in leaves
Authors: Bhunia Rupam Kumar , Menard Guillaume N. , Eastmond Peter J.
Published: May 2022

Achieving gain‐of‐function phenotypes without inserting foreign DNA is an important challenge for plant biotechnologists. Here, we show that a gene can be brought under the control of a promoter from an upstream gene by deleting the intervening genomic sequence using dual‐guide CRISPR/Cas9. We fuse the promoter of a nonessential photosynthesis‐related gene to DIACYLGLYCEROL ACYLTRANSFERASE 2 (DGAT2) in the lipase‐deficient sugar‐dependent 1 mutant of Arabidopsis thaliana to drive ectopic oil accumulation in leaves. DGAT2 expression is enhanced more than 20‐fold and the triacylglycerol content increases by around 30‐fold. This deletion strategy offers a transgene‐free route to engineering traits that rely on transcriptional gain‐of‐function, such as producing high lipid forage to increase the productivity and sustainability of ruminant farming.
The activator/repressor Hap1 binds to the yeast eIF5A‐encoding gene TIF51A to adapt its expression to the mitochondrial functional status
Authors: Barba‐Aliaga Marina , Alepuz Paula
Published: May 2022

Mitochondrial activity adapts to cellular energetic and metabolic demands; its dysfunction is a hallmark of ageing and many human diseases. The evolutionarily conserved translation elongation factor eIF5A is involved in maintaining mitochondrial function. In humans, eIF5A is encoded by two highly homologous but differentially expressed genes; in yeast, these are TIF51A and TIF51B. We show that yeast transcription factor Hap1 constitutively binds to the TIF51A promoter to activate its expression under respiration, but represses its expression under nonrespiration conditions by recruiting the corepressor Tup1. Hap1 indirectly regulates TIF51B expression by binding to and activating the TIF51B repressor genes ROX1 and MOT3 under respiration and repressing them under nonrespiration. Thus, the levels of eIF5A isoforms are adapted to the mitochondrial functional status.
Intramolecular Arylation of 2‐Bromobenzenesulfonamides Using DMSO/HCOONa ⋅ 2H2O System: An Access To Dibenzosultams
Authors: Hao Feiyue , Liu Guyue , Jin Zhengneng , Dai Guoliang , Nishiwaki Nagatoshi , Wu Jiashou
Published: May 2022

Six‐ or seven‐membered dibenzosultams were synthesized upon treatment of N‐aryl‐ or N‐benzyl‐2‐halobenzenesulfonamides with HCOONa ⋅ 2H2O in DMSO without using additional measures and additives, such as light irradiation, electrochemical apparatus, transition metals, and oxidants. Further functionalization of the free NH group of the resultant dibenzosultams demonstrates the synthetic practicability of this method.

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A Memristor‐Based Bioinspired Multimodal Sensory Memory System for Sensory Adaptation of Robots
Authors: Pan Xinqiang , Wang Jiejun , Deng Zhen , Shuai Yao , Luo Wenbo , Luo Wen , Xie Qin , Xiao Yao , Tang Song , Jiang Shuwen , Wu Chuangui , Zhu Feng , Zhang Jianwei , Zhang Wanli
Published: May 2022

Sensory adaptation plays a critical role in humans interacting with the environment. Inspired by humans, realization of sensory adaptation on robots can make them adapt to the environment gradually. The gradual change of sensitivity that depends on recent experience of external stimuli is the most important process for the adaptation. To realize sensory adaptation, such change of sensitivity needs to be realized. It is proposed to fabricate the memristor based on single‐crystalline LiNbO3 thin film. The resistance of the memristor can be changed monotonically and gradually with the increase in the number of voltage pulses, which can be ascribed to the property of single‐crystalline thin films. Based on the characteristic, it is proposed to use the memristor as artificial synapse of the proposed bioinspired system, using conductance of the memristor to denote susceptibility value to realize the gradual change of sensitivity by recent external stimuli. A novel general excitation method of signals from multimodal sensors on memristor is proposed and utilized in the signal‐coupling module of the system, which makes the system realize sensory adaptation for different stimuli accepted by multimodal sensors. Using artificial sensory memory systems, sensory adaptation on robot is realized for the first time herein.
Porous Organic Salts: Diversifying Void Structures and Environments
Authors: Ami Takahiro , Oka Kouki , Tsuchiya Keiho , Tohnai Norimitsu
Published: May 2022

Porous organic salts (POSs) are porous organic materials, in which various aromatic sulfonic acids and amines are regularly self‐assembled by charge‐assisted hydrogen bonding. POSs exhibit high solubility in highly polar solvents. Therefore, they are prepared via facile recrystallization and exhibit high recyclability. In this study, tetrahedral‐structured tetrasulfonic acid and triphenylmethylamine (TPMA) were combined to construct POSs with rigid diamond networks called diamondoid porous organic salts (d‐POSs). Furthermore, by introducing substituents (e.g., F, Cl, Br, or I) at the para‐positions of benzene rings of TPMA, these substituents were exposed on the void surface of d‐POSs, and their diamond networks were distorted. This induced the formation of a variety of void structures and environments in the d‐POSs, which significantly affected their gas adsorption behavior. In particular, the d‐POS from TPMA substituted by fluorine exhibited very high CO2 adsorption of 182 mL(STP) g−1 at 1 atm in all‐organic porous materials.
Excitation‐Dependent Circularly Polarized Luminescence from Helical Assemblies Based on Tartaric Acid‐Derived Acylhydrazones
Authors: Xue Chenlu , Jiang Yuqian , Wang Han‐Xiao , Du Cong , Xu Lifei , Li Tiesheng , Liu Minghua
Published: May 2022

Here, we combined the merits of emergent excitation‐dependent (ExD) emission and circularly polarized luminescence to develop an excitation‐dependent circularly polarized luminescence (ExD CPL) material showing unique features. A series of acylhydrazones based on a chiral tartaric skeleton was designed and found to self‐assemble into helical nanostructures through non‐covalent bonds. The helical assemblies showed ExD CPL due to the cooperation of chirality transfer and excited state intramolecular proton transfer (ESIPT). Remarkably, not only the emission wavelength could be tuned by the excitation wavelength but the handedness of CPL could be modulated in an inverted or ON/OFF manner as well, thus leading to the first example of an ExD inverted or ON/OFF switchable CPL system. Time‐dependent density functional theory (TD‐DFT) calculations were carried out to explain the inversion of ExD CPL. This work provided a new insight into the unprecedented handedness controllable ExD CPL, which showcased a new paradigm of the advanced CPL materials.