bluuebunny/crossref_metadata_2025 huggingface dataset:
Gabor wavelet and multiclass support vector machine for braille image classification
Authors: Agustina Feri , Rachmawanto Eko Hari , Putri Ni Kadek Devi Adnyaswari , Saputro Fakhri Rasyid , Lestiawan Heru , Suprayogi Suprayogi , Huda Solichul
Published: December 2024

Braille is a letter designed for the visually impaired. As a family with normal vision who have a visually impaired child find it difficult to Teach their child how to learn and understand the process of learning from home. Learning braille requires good finger sensitivity and memory to memorize each letterform, making it difficult to learn.  With this study, braille letters can be detected from the image using the Gabor Wavelet method to extract braille images and combined with the Multiclass Support Vector Machine (Multiclass SVM) algorithm as a classification method for extracted braille images. Data testing was performed using a confusion matrix to determine the level of precision, accuracy, and recall. According to the results of tests performed on 910 braille data using confusion matrix, the highest recognition accuracy was 98,02%. The accuracy of these results is impacted by the parameters of the training process, the training data, and the test data used. This research has the opportunity to be developed in voice-based card recognition to help the visually impaired in the future research.
Self-Efficacy of Breast Self-Examination among Female Adolescents
Authors: C. E. Abaribe, , N. A. Okafor, , F. O. Opatunji, , J. O. Maitanmi, , T. A. Leslie, , C. C. Asonye, , C. U. Eze-Adiele,
Published: December 2024

Self-efficacy refers to an individual’s ability to perform a task confidently and successfully. Self-efficacy of breast self-examination is key to early detection of any abnormality that could lead to breast cancer. Evidence has shown a correlation between self-efficacy of breast self-examination and performance of breast self-examination. Self-efficacy of breast self-examination could be determined by performance accomplishments, vicarious experience (learning from people or observing breast self-examination being done), verbal persuasion (encouragement received from someone to perform breast self-examination), and physiological/emotional states (emotional reactions to performing breast self-examination). Female adolescents should be educated to acquire self-efficacy to perform breast self-examination since adolescence is a critical period for developing lifelong habits, attitudes, forming health-related lifestyles, and behaviours for the future. Breast self-examination performed monthly at the right time using the right techniques will aid in the early detection of breast cancer. Consistent breast self-examinations are the best protection in detecting early breast cancers.
Valorization of Baco Noir grapes in the technology of obtaining of gummy candies
Authors: Boistean Alina , Chirsanova Aurica , Gaina Boris
Published: December 2024

The number of people suffering from food allergies is continuously increasing. Allergic reactions to synthetic additives widely used in candy production are part of this category. The aim of this study was to develop alternative gummy candies based on natural ingredients that substitute synthetic analogs, as well as to study their effect on organoleptic and microbiological characteristics. The developed candies contain Baco Noir grape juice as a source of color, flavor, and biologically active compounds. Organic wine vinegar was added as a natural preservative and color stabilizer. The results showed that the mass fraction of moisture in the candies is overestimated and varies from 70 to 75%. This is explained by the replacement of sugar with honey and the use of liquid ingredients: juice and vinegar. At the same time, the samples proved to be microbiologically stable, indicating the positive antimicrobial effect of the natural ingredients.
The course of pregnancy in a Rhesus-negative patient
Authors: Capros Hristiana , Athanasiadis Apostolos
Published: December 2024

Feto-maternal isoimmunization is a complex phenomenon in which the maternal immune system produces antibodies directed against antigens present on fetal blood cells. A common example of feto-maternal immunization is Rh isoimmunization, which occurs when an Rh-negative mother is exposed to the blood of an Rh-positive fetus. Maternal-fetal Rh isoimmunization causes more than 160,000 perinatal deaths and 100,000 cases of disability each year. In order to reduce perinatal mortality and morbidity from this pathology, recent guidelines from the French Society of Obstetrics and Gynecology (CNGOF, 2017), the International Federation of Gynecology and Obstetrics (FIGO, 2021), and the Canadian Society of Obstetrics and Gynecology (SOGC, 2024) have revised the management of pregnancy in Rh negative patients. In line with these recommendations, blood type and Rh determination is part of the recommended early pregnancy screening, ideally at the first antenatal visit. In non-immunized Rh-negative pregnant women with an Rh-positive partner, a non-invasive prenatal test can be recommended: Rh determination based on fetal acellular deoxyribonucleic acid present in maternal blood. Routine administration of anti-RhD immunoglobulin prenatally (at 2834 weeks amenorrhea (SA) and postpartum (within 72 hours after delivery) to unimmunized patients with Rh-positive infants allows reduction of feto-maternal sensitization.
Social listening on immunization: complementing the online perspective with that of family doctors, nurses and teachers
Authors: Timotin Alina , Paladi Adriana
Published: December 2024

The infodemic has boosted the use of social listening techniques in public health and highlighted the need to complement the online and offline perspectives. Thus, through qualitative studies carried out offline, we aimed to identify potential aspects of misinformation that would serve as barriers to population vaccination. Between September 2023 and April 2024, five focus groups were held, with a total of 37 participants. The text derived from the transcripts of the records was analyzed, and based on the synthesis of this qualitative data, findings were formulated, supported by quotes. Ten themes confirming vaccine hesitancy have been identified: mistrust (in doctors, authorities, vaccines, system, manufacturers), fears and reluctance to vaccination, communication, rumors and poor resilience to misinformation, intra- and inter-sectoral collaboration, legislation and mandatory vaccination, role of communities, falsification of vaccination cards, limited time of doctors and measles. The abundance of information, including false information, disseminated through the media, social networks and parents` groups is a barrier to vaccination. Some parents refuse vaccination without being able to give a reason and without being aware of possible consequences. A serious problem confirmed by doctors and teachers is the illegal completion of vaccination records. Teachers show poor resilience to misinformation. Both family doctors and teachers mention the importance of intensifying intersectoral collaboration.
The impact of tourism management on the increase of economic competitiveness
Authors: Costețchi-Jusca Oxana , Gavrilas Natalia
Published: December 2024

Nowadays the tourism sector is gaining ground and making a significant contribution to the economic development of a country. Tourism management, whose major objective is to develop tourism through the planning, organization and managing all the activities within this sector, greatly influences the economic course. The purpose of this research is to highlight the impact of tourism management on increasing national economic competitiveness. It also presented the evolution of the tourism sector in the Republic of Moldova in the last four-five years, its contribution to the Gross Domestic Product. Among the most relevant deductions are the significant contribution of the tourism sector to job creation and unemployment reduction. The 70% increase in the average gross monthly wage in 2018–2023, with a 26% increase in 2021–2022, highlights a notable recovery of the sector after the pandemic crisis. At the same time, spending by non-resident tourists increased palpably, strengthening Moldova's attractiveness as a tourist destination, which contributed to a 7% increase in national GDP in 2023. At global level, tourism contributed 9.1% to world GDP in 2023, and Moldova has followed this trend. Also, in 2022, exports of travel services brought a surplus in the balance of trade in services, including as a result of the influx of refugees from Ukraine in the context of the war in the region. In contrast, domestic tourism experienced a decline in 2023, with Moldovans increasingly opting to travel abroad, reflecting a return to pre-pandemic normality and a diversification of tourism preferences. These results demonstrate that effective tourism management contributes directly to the development and strengthening of Moldova's competitive economy. The methodology used in this research consists in the study and analysis of the literature, the analysis and systematization of statistical data and the elaboration of graphs. The originality lies in presenting and analyzing the impact of tourism management on the growth of economic competitiveness.
Generational perspectives on organizational change
Authors: Melnic Anisoara
Published: December 2024

Change is ubiquitous, being a constant element that impacts both individuals and organizations. This article makes a brief foray into the concept of organizational change and generations. It also elucidated the factors that influence the workforce’s response to organizational change: personal interest (personal costs of adapting to change), psychological reasons (fear of the unknown, fear of not adapting to change), emotional reasons (loss of motivation, denial of the need for change), approach to change (lack of communication, non-participation), perception of change (lack of understanding of what needs to be done and expected results, negative experiences related to change), cultural biases (change in habits of doing things, conflict between change vs values and beliefs of recipients), historical organizational relationships (nature of employee-manager relationship, internal rivalries). In this article, the perspective of different generations of employees on the phenomenon is examined as a matter of priority. The literature reports rather equivocal results regarding the degree of openness or resistance to change of the various generations, but somewhat shifts the difficulty of understanding the phenomenon. The work aims to support managers in increasing their ability to cope with the ever-changing environment, as well as the skills to effectively manage different generations of employees along the way.
Classification of Dopamine D2 receptor ligands using RDKit Molecular descriptors and Machine Learning Algorithms
Authors: Suprapto Suprapto , Lailun Ni’mah Yatim
Published: December 2024

Identifying and classifying dopamine D2 receptor agonists and antagonists is essential for the drug discovery and development. In this study, we employed machine learning algorithms, namely, XGBoost, LGBM, ExtraTree, and AdaBoost Classifier, in combination with RDKit molecular descriptors, to classify dopamine D2 receptor ligands. The dataset consisted of 195 molecules, comprising 69 dopamine agonists and 126 dopamine antagonists. The models were trained using 75% of the dataset and evaluated on the remaining 25%. The classifiers demonstrated high accuracy and F1 scores, with the AdaBoost Classifier achieving the highest accuracy of 92%. Receiver operating characteristic (ROC) analysis further confirmed the robustness of the model, as indicated by the area under the curve (AUC) values. The AUC values for the AdaBoost, Extra Tree, LGBM, and XGB classifiers were 0.92, 0.90, 0.87, and 0.89, respectively. Feature selection analysis revealed the important molecular descriptors that significantly contribute to the classification models. The ExtraTree classifier selected the highest number of descriptors (167), while the intersection of the selected descriptors among all models indicated 24 common features that crucial for classification. Classification of external compounds using the developed models revealed that sinedabet was classified as a dopamine D2 receptor antagonist, while lisuride, ropinirole, and quinpirole were classified as dopamine D2 receptor agonists.
The Potential of Nail Glycation Examination for Detecting Diabetes Mellitus: A Systematic Review and Meta-Analysis
Authors: Cahyaning Ratri Lintang , Laras Pramudito Shidi , Samarta Witarto Bendix , Hendro Prajitno Jongky , Dyah Kencono Wungu Citrawati , Novida Hermina , Dwitama Adiwinoto Robert
Published: December 2024

Objectives: Over the years, the increasing number of diabetes mellitus cases has drawn special attention in which diabetes screening becomes a crucial effort to prevent burdensome complications. The current practice of screening and monitoring diabetes mellitus requires an invasive method to retrieve blood samples, which may be inconvenient to patients. However, no meta-analysis has examined hyperglycemia conditions in nail protein compositions. Therefore, this study aims to identify the potential of nail glycation examination as a non-invasive diagnostic tool in diabetes mellitus. Methods: A systematic search was conducted in electronic databases and the collected literatures then were further reviewed. A bivariate random-effect meta-analysis was conducted to estimate the pooled parameter of diagnostic values. The study protocol was registered in PROSPERO CRD42021267633. Results: The five studies with a total of 885 participants included in this study yielded a pooled result of sensitivity and specificity reaching 87% (95% CI: 0.57‒0.97) and 93% (95% CI: 0.69‒0.99), with the area under the curve of 96% (95% CI: 0.94‒0.97). Conclusion: In conclusion, nail glycation examination has good potential as a non-invasive diagnostic tool in diagnosing diabetes mellitus.
Optimal timing of urinary catheter removal after cesarean section; Randomized controlled trial
Authors: Ahmed Nancy , Torad Hesham , Nagy Omar , Elsayed Khayal Ali , El-Nahhas Kareem , farouk Hussein mohamed Basma , Samir Hamid Shaaban Ahmed , Hamdy Ahmed Keshta Nawal , Barakat Abu Elyazid Shatat Hanan , Abdelkhalek Ahmed Abdelkader Rehab , Sedki Yassin Ali Mahmoud , Salah eldien elkady Maged , Yahia Mahmoud Marwa
Published: December 2024

Background: Urethral catheterization plays a major role for reducing the likelihood of bladder damage and avoiding urinary retention before and after cesarean section, we aim to investigate the optimal time of removal catheter after cesarean section. Material And Method: A total of 250 eligible women, who were eligible for either primary or repeat elective cesarean section, were randomly assigned to two equal groups in a prospective randomized controlled study. In group A, the catheter was removed two hours after the surgery, whereas in group B, the catheter was extracted after 12 hours. Result: our study found that group of early catheter removal (2h) associated with lower events than delayed catheter removal (12h), early catheter removal (2h) associated with less bacteriuria, urinary retention, urgency, dysuria, burning on micturition and urinary frequency. We also found that early catheter removal (2h) over delayed catheter removal (12h) in postoperative outcomes as Postoperative mobilization, Postoperative oral rehydration, First postoperative voiding and Hospital stays. Conclusion: Early removal of the catheter is associated with less bacteriuria, urinary retention, urgency, dysuria, burning on micturition, and urinary frequency and did not enhance the urinary tract infection.
Rèn luyện tư duy phân tích cho học sinh lớp 12 thông qua dạy học chủ đề "Phương pháp tọa độ trong không gian”
Authors: Nguyễn Dương Hoàng , Phạm Thị Thắm
Published: December 2024

Bài viết trình bày các đặc trưng của tư duy phân tích trong dạy học Toán. Từ việc nghiên cứu các tài liệu về tư duy, tư duy phân tích và thực tế giảng dạy môn Toán tại trường phổ thông, chúng tôi đề xuất một số biện pháp góp phần rèn luyện tư duy phân tích cho học sinh lớp 12 thông qua dạy học chủ đề “Phương pháp tọa độ trong không gian”.
Mapping Educators’ Knowledge, Perceptions, and Readiness (KPR) towards the Adoption of Extended Reality (XR) Technologies in the Classroom (KPR-XR): Scale Development and Validation
Authors: Choudhury Sourav , Dutta Indrajeet
Published: December 2024

This research endeavor aimed to develop and validate a comprehensive scale to assess educators’ knowledge, perceptions, and readiness (KPR) towards the adoption of Extended Reality (XR) technologies in classroom settings. XR (Virtual Reality -VR, Augmented Reality-AR, and Mixed Reality-MR) has transpired as a ground-breaking tool within the educational landscape, but its effective integration completely relies on educators. Grounded in three theoretical frameworks- Technological Pedagogical Content Knowledge (TPACK) for Knowledge, Technology Acceptance Model (TAM) for Perception, and Unified Theory of Acceptance and Use of Technology (UTAUT) for Readiness- the initial scale included 41 items that were drawn/inspired from different papers published in international journals. After this, expert reviews and Content Validity Index (CVI) calculation were undertaken, which resulted in three items being removed, resulting in a 38-item scale. The scale was then administered to 700 University educators across India in the mid of 2024. Exploratory Factor Analysis (EFA) and Confirmatory Factor Analysis (CFA) validated the scale structure, confirming three distinct dimensions (KPR) with strong internal consistency (> 0.90). The KPR-XR scale offers a reliable means to examine the critical factors (KPR) that influence educators' adoption of XR technologies, providing important implications for educational practice and policy.
A Comparative Analysis of Swarm Intelligence Algorithms for Event Detection in Wireless Sensor Networks
Authors: Boshra Fakhry Alsarayreh
Published: December 2024

WSNs play an important role in monitoring and responding to dynamic events in applications such as disaster management, industrial automation, and environmental monitoring. Since event detection has the highest priority in a WSN, it is very crucial regarding timely response, energy efficiency, and system reliability. However, traditional threshold-based detection methods often lack flexibility and always consume large amounts of energy. SI algorithms, motivated by natural collective behaviors, offer robust and adaptive solutions for event detection in order to overcome the limitations of conventional methods.
Performance analysis and comparison of three most powerful SI algorithms - DA, ACO, and PSO - for event detection in WSNs. Methods: The performance of these algorithms was analyzed for time efficiency, energy consumption, accuracy, and scalability using simulation-based experiments. The experiments simulate WSNs of different node densities and event characteristics on the widely used python and MATLAB platforms under identical conditions for each algorithm.
Among them, the Dragonfly Algorithm outperformed ACO and PSO in time efficiency-66.48 seconds versus 85.10 and 77.03 seconds, respectively-energy consumption (0.000030 J vs. 0.000047 and 0.000035 J), and accuracy, 94.5% versus 92.1% and 93.2%, correspondingly. DA also has better scalability for different network sizes and performs consistently well for larger networks, up to 1024 nodes. ACO, though robust in path exploration, had the highest energy consumption and longest detection time, which seriously affects its scalability. PSO gave balanced performance, though it trailed DA significantly in key metrics.
The Dragonfly Algorithm provides the most efficient and scalable solution for WSN event detection with high time efficiency, energy conservation, and accuracy. These results underline its applicability in real-world time-critical and energy-sensitive WSN applications.
Challenges Faced by Higher Educational Institutions in Implementing NEP 2020
Authors: G. Nagamani
Published: December 2024

The National Education Policy (NEP) 2020 transforms India's education system by stressing comprehensive, transdisciplinary, and inclusive learning. This policy aims to match the Indian education system with global norms while retaining its cultural and philosophical history, and higher education institutions (HEIs) are crucial to its success. NEP 2020 envisions an education system that fosters creativity, critical thinking, and ethics to prepare students for real-world situations. From curriculum redesign to faculty training and infrastructure development, NEP 2020 requires HEIs to remodel their structures. Institutions must stimulate research and innovation, integrate multidisciplinary curricula, and offer many entry and departure possibilities. These reforms offer academic excellence but also bring problems, particularly in institutional preparation, funding, and digital infrastructure. The National Education Policy (NEP) 2020 aspires to transform India's educational framework, emphasizing inclusivity, innovation, and alignment with global standards. This study examines the obstacles encountered by higher educational institutions (HEIs) in the implementation of the National Education Policy (NEP) 2020, as well as the determinants that affect its successful execution. Drawing upon a sample of 82 respondents, the research delineates significant impediments, including insufficient digital infrastructure, limitations in funding, and a lack of awareness regarding relevant policies. Through the application of chi-square and regression analyses, the study elucidates the significance of institutional preparedness and financial support in facilitating successful implementation. The findings highlight the necessity for focused interventions aimed at addressing regional disparities and enhancing the capacity of higher education institutions (HEIs).
Absceso cerebral con foco de origen odontogénico. Reporte de un caso

//Brain abscess with a focus of odontogenic origin. A case report
Authors: Giménez Fabián , Cuesta María Paula
Published: December 2024

Objetivo: Presentar el caso de un paciente con un absceso cerebral con foco de origen odontogénico.

Caso clínico: Un paciente de 30 años llega al servicio de emergencias del Hospital Interzonal General “Dr. José Penna” de Bahía Blanca con cefalea intensa de siete días de evolución. Se diagnosticó absceso cerebral, por lo que se realizó cirugía de drenaje y tratamiento con antibióticos. El origen fue una infección odontogénica, que fue tratada en el servicio de odontología. Un examen médico exhaustivo no reveló otras fuentes de infección. En el absceso cerebral se aisló Streptococcus viridans. Este caso enfatiza la importancia de la interdisciplina entre la neurología y la odontología en la prevención de abscesos cerebrales con foco de origen odontogénico.

//Aim: To report a case of a patient with a brain abscess with a focus of odontogenic origin.

Clinical case: A 30-year-old male patient arrives at the Emergency Service of the Interzonal General Hospital “Dr. José Penna” from Bahía Blanca with an intense headache lasting seven days. A brain abscess was diagnosed, so drainage surgery and treatment with antibiotics were performed. The origin was an odontogenic infection, which was treated in the Dentistry Service. A thorough medical examination revealed no other sources of infection. Streptococcus viridans was isolated from the brain abscess. This case emphasizes the importance of interdisciplinary work between neurology and dentistry, in the prevention of brain abscesses with a focus of odontogenic origin.
Use of the esophageal catheter to detect asynchronies
Authors: Perez Vivtor , Pasco Jamille
Published: December 2024

Patient-ventilator asynchronies are more usual than we believe in critical care patients, and recognition of such an interaction can be challenging in clinical practice, especially if we don´t have advanced monitoring tools such as esophageal pressure tracing at the bedside.
Reverse trigger, early cycling, and work shifting are types of asynchronies that must comply with some characteristics in the interaction between ventilator and patient, that could be difficult to detect only with visual analysis of usual waveforms curves showed in mechanical ventilators even for trained operators.
In this sense, esophageal catheter is a very useful tool to correct detection and management, if required, of patient-ventilator interactions.

Keywords: asynchrony, esophageal pressure, reverse trigger, work shifting.
Analisis Gradeless terhadap Kemampuan Berpikir Kreatif Matematis
Authors: Fajar Ikhsan Nur , Isnani Isnani , Ahmadi Ahmadi
Published: December 2024

Gradeless merupakan suatu penilaian pada lembar kerja peserta didik tanpa menambahkan huruf dan angka tetapi memberikan feedback dalam masing-masing pekerjaan peserta didik. Tujuan penelitian ini ialah mendiskripsikan pengaruh gradeless pada kemampuan berfikir kreatif peserta didik SMP kelas viii. Adapun metode yang diterapkan diantaranya metode penelitian kualitatif dengan subyek sejumlah 6 peserta didik kelas VIII SMP Al Manshuriyah Tahun Ajaran 2020/2021. Pemilihan sampel melalui teknik purposive sampling dan kriteria bermasalah (kurang aktif saat pembelajaran, sering terlat mengumpulkan tugas, dan jarang memperhatikan saat pembelajaran berlangsung) yaitu sejumlah 6 peserta didik. Teknik pengumpulam data melalui dokumentasi, tes dan wawancara. Teknik analisis data  penelitian ini memakai model Miles dan Huberman Sugiono yakni mengumpulkan  data, reduksi data, menyajian data serta verifikasi. Sesuai pada hasil analisis data yang didapat disimpulkan yakni secara umum gradeless bisa mempengaruhi baik bagi subyek penelitian. Ketika diberikan umpan balik pada kegiatan gradeless subjek penelitian lebih dapat memahami dan mengetahui kesalahan atas jawaban subjek penelitian, sehingga subjek penelitian dapat mempelajarinya kembali. Hal ini dapat memberikan dampak positif untuk semua jenis peserta didik. Adapun saran yang diajukan untuk peserta didik diharapkan agar lebih memperhatikan dan peduli dengan apa yang sedang dipelajarinya dan masih ada yang lebih perlu atau penting dari sebuah nilai yaitu sebuah proses belajar itu sendiri.
Isolation, optimization, and redesigning of phages of methicillin-resistant Staphylococcus aureus from clinical hospital isolates in Baghdad
Authors: Hafidh Rand R. , Hafidh Mohammed R. , Kadhim Nisreen Jawad , Abdulamir Ahmed S.
Published: December 2024

Background: A global health concern is methicillin-resistant Staphylococcus aureus (MRSA). The use of bacteriophages is one of the many novel control strategies against MRSA that are frequently sought. However, it is quite challenging to isolate enough lytic anti-MRSA phages. In order to extract, optimize, and remodel anti-MRSA phages, this study sought novel approaches.

Methods: Two ATCC MRSA strains and nine clinical MRSA isolates were used to isolate wild anti-MRSA phages from hospital settings, dirt, and sewage. The wild phages were optimized using plaque-based biokinetic techniques. Using chemicals that weakened bacterial cell walls, the resulting highly lytic and specific anti-MRSA phages were subjected to unique physicochemical phage redesign processes. This allowed the phages to enter host bacteria and acquire the specificity of the new host. Three different protocols were tested using combinations of Tween 20, lysozyme, and nisin A.

Results: Nisin A and lysozyme protocols at different rates were found to be successful in producing newly redesigned, transiently stable, anti-MRSA phages.

Conclusion: Unlike self-depleting antibiotic-based applications, phage redesign is self-fortifying. In order to address the increasing number of epidemic MRSA strains, this model could prove to be a perfect platform for developing trustworthy control and treatment strategies. Additionally, it is believed to be an infinite supply of anti-MRSA lytic phages from which several permanent phage lysins can be isolated and refined.
Un enfoque epidemiológico de Ehrlichia canis en perros del cantón Durán de la provincia del Guayas, Ecuador
Authors: Mendoza Castañeda Georgia Elena , Rojas Córdova Karla Katherine , Vaca Navarro Gilda Doménica
Published: December 2024

El objetivo de la presente investigación fue determinar la seroprevalencia de Ehrlichia canis en perros de dos sectores del cantón Durán de la Provincia del Guayas, Ecuador; esta es una bacteria intracelular, de distribución mundial que afecta a las células mononucleares de los hospedadores susceptibles y es transmitida por las garrapatas, cabe indicar que el clima de la zona estudiada presenta las características necesarias para la proliferación del vector y como consecuencia la presencia del hemoparásito. La unidad de análisis los perros, el tipo de investigación fue descriptivo, no experimental, transversal y correlacional, tuvo como muestra a 30 perros mayores a 6 meses de edad, se utilizó un cuestionario estructurado como instrumento de recopilación de datos y se aplicó una encuesta a los dueños. Las muestras fueron analizadas mediante técnica de inmunocromatografía utilizando el Test Bioguard, los datos fueron evaluados mediante el Software SPSS versión 27, donde se determinó un 46,66% de seroprevalencia de Ehrlichia canis, al hacer un análisis correlacional entre variables independientes y dependientes se determinó que no hay asociación entre ellas.
Seroprevalencia de Leishmania spp., en perros del cantón Durán, provincia del Guayas, Ecuador
Authors: Mendoza Castañeda Georgia Elena , Macías Litardo María Fernanda , Granoble Pincay Mercedes Johanna
Published: December 2024

Actualmente, las enfermedades zoonóticas deben mantener un estudio constante para identificar la presencia de vectores y establecer posibles zonas endémicas. En el presente estudio se determinó la presencia de Leishmania spp., en perros del cantón Durán, de la provincia del Guayas, Ecuador, mediante la prueba inmunocromatográfica Bionote Leishmania Antibody. En la investigación se utilizó un enfoque cuantitativo, con un diseño de investigación tipo descriptiva, transversal, no experimental. Utilizando el método de muestreo no probabilístico por conveniencia. La población por estudiar fue de 30 perros seleccionados pertenecientes a dos sectores del cantón Durán. Los resultados muestran un caso positivo, estableciendo el 3 % de seroprevalencia para identificar Leishmania spp. Finalmente, el único caso positivo, fue un animal adulto que presentó un mayor tiempo de permanencia fuera de casa, estableciendo una prevalencia baja en la zona para la enfermedad leishmaniosis.
Integrating pharmacogenomics into nursing practice implications for clinical decision-making
Authors: Alyamani Abdullah Mohammed Abdullah , Alruqaie Reef Ibrahim Mohammed , Albather Mohammed Hassan , Alamri Badr Jaza , Alharbi Majed Ayidh
Published: December 2024

Background: Integrating pharmacogenomics (PGx) into nursing practice has the potential to enhance personalized medicine and improve clinical decision-making. Despite its growing relevance, barriers such as insufficient training, limited knowledge, and unclear clinical guidelines hinder the adoption of PGx in nursing. Methods: This study employed a mixed-method systematic review using a convergent integrated approach to explore intrinsic and extrinsic factors influencing nurses' adherence to Clinical Practice Guidelines (CPGs) in PGx. A comprehensive literature search was conducted across multiple databases, synthesizing quantitative and qualitative findings to identify key determinants of adherence. Results: Key intrinsic factors identified include nurses’ baseline knowledge, attitudes, and confidence in applying PGx-related CPGs. Extrinsic factors encompassed institutional support, access to training programs, integration of PGx into electronic health records, and interdisciplinary collaboration. Barriers such as a lack of standardized CPGs and resource limitations were also highlighted. The synthesis revealed that tailored educational interventions and robust support systems significantly improved adherence rates. Furthermore, a strong correlation between interdisciplinary teamwork and effective CPG implementation was noted. Conclusion: Successful integration of pharmacogenomics into nursing practice requires addressing both intrinsic and extrinsic barriers. Strategies such as enhanced education, clear guidelines, and systemic support are essential for fostering adherence to PGx CPGs.
Desinfecção por Vapor de Peróxido de Hidrogênio no Transplante de Fígado: Efeitos na Colonização de Organismos Multirresistentes e nos Resultados do Receptor
Authors: Silveira Fábio , Silveira Fábio Porto , Silveira Csaaia Regina Sbrissia , Facchi Tatiana Luisa Shibata , Costa Ellen Dalla , Itinose Kengi
Published: December 2024

Introdução: A escalada das infecções por organismos multirresistentes (MR) pós-transplante de fígado (TF) representa riscos significativos, com a colonização por MR amplificando a suscetibilidade à infecção. A desinfecção ambiental é crucial para conter as infecções associadas à assistência à saúde (IRAS). A tecnologia de vapor de peróxido de hidrogênio (VPH) oferece promessas, mas seu impacto nas infecções por MR e nos resultados dos pacientes ainda não está claro. Métodos: Um estudo de coorte incluiu 58 receptores de TF adultos, comparando os resultados antes e depois da implementação rotineira do VPH. A desinfecção por VPH seguiu a limpeza terminal em salas cirúrgicas e boxes de unidade de terapia intensiva. Os dados dos patógenos incluíram colonização por MR no pré- e pós-transplante. Os dados clínicos abrangeram características dos receptores, gravidade da doença e características do binômio doador-receptor. As análises estatísticas avaliaram associações e resultados. Resultados: Vinte e sete pacientes estavam no grupo antes do VPH e 24 no grupo após o VPH. As características demográficas e clínicas foram comparáveis entre os grupos. A implementação do VPH aumentou significativamente a probabilidade de resultados negativos nos swabs de controle (razão de chances 2,33). Klebsiella pneumoniae carbapenemase foi o patógeno mais frequente, com infecções do sítio cirúrgico sendo o local primário mais comum. Pacientes com swabs negativos tiveram internações hospitalares mais curtas (diferença média de 10,54 dias), divergindo notadamente por volta do 8o dia de internação. A frequência de IRAS e a mortalidade em 90 dias foram significativamente menores em pacientes com swabs negativos. Conclusão: A tecnologia de VPH reduziu efetivamente a colonização por MR em receptores de TF. Swabs negativos se correlacionaram com internações hospitalares mais curtas e menor frequência de IRAS, impactando positivamente a mortalidade em 90 dias. Apesar dos desafios na implementação do VPH, sua eficácia na redução da colonização por MR sugere uma ferramenta valiosa nas estratégias de controle de infecções para populações vulneráveis como receptores de TF.
Family Justifications for Not Authorizing Organ Donation: Documentary Study
Authors: Batista Maria Eduarda Pasquotto , Telles Clayton Felipe da Silva , Pierotto Aline Aparecida da Silva , Barilli Sofia Louise Santin , Rocha Katiane Rosa da , Rosa Rafael Ramon da , Peradotto Brenda Carvalho , Treviso Patricia
Published: December 2024

Objectives: To understand the reasons given by family members for not authorizing the donation of organs and tissues. Methods: This is a documentary study. The records of interviews with the families of potential donors, conducted in 2022 by the Organ and Tissue Procurement Organization in the state of Rio Grande do Sul, were analyzed. The study included records related to refusals for donation. Incomplete records or those lacking the family's justification were excluded. Data were collected in March and April 2024 and analyzed using simple descriptive statistics. The research project was approved by the Research Ethics Committee. Results: During 2022, the OPO conducted 121 interviews with family members of potential organ donors; of this total, there were 33 authorizations, 65 refusals, and 23 cases of medical contraindications for donation. Regarding family refusals, of the 65 records analyzed, 39 were excluded due to incomplete information or because they did not contain the justification for refusal. The final sample consisted of 26 interview records. The most common arguments for refusing donation were the patient was not a donor in life, the family was unaware of the deceased’s wishes regarding donation, and the family expressed opposition to donation. Conclusion: The observed justifications included the deceased having declared themselves not to be a donor in life, lack of family consensus on donation, the family’s desire to preserve the integrity of the body, the wait time for the return of the body, religious reasons, unawareness of the deceased’s wishes regarding donation, and family opposition to donation. The results may be used by professionals in various healthcare services to develop strategies to mitigate family refusals.
Evaluasi Layanan Internet Reactor Laboratory Reaktor Kartini Berdasarkan Peraturan Menteri PANRB Nomor 14 Tahun 2017
Authors:   Direktorat Pengelolaan Fasilitas Ketenaganukliran, Badan Riset dan Inovasi Nasional, Yogyakarta, Putrianti Okviandra , Wicaksono Argo Satrio
Published: December 2024

Kartini Reactor is one of Indonesia's research reactors that is used to learn nuclear technology. One of its services is the Internet Reactor Laboratory (IRL) with online Synchronous Learning-based implementation. To fulfill laws and regulations related to public services, meet the targets of BRIN agency work units, and evaluate to achieve excellent service, a survey is needed to assess the quality of IRL services in a Community Satisfaction Index (IKM) and Community Satisfaction Survey (SKM) using the guidelines of the Minister of PANRB Regulation Number 14 of 2017. The data collection method uses an e-questionnaire distributed to service users, which is then analyzed quantitatively. At the same time, the follow-up improvements use qualitative methods with interviews and observations. The survey results are used to evaluate and improve services to provide excellent service and fulfill community expectations and demands. The results of the quantitative analysis obtained that the results of the service IKM were 3.50 (maximum scale 4.00), and the service SKM value was 87.48 (maximum scale 100), which is included in the category of service quality B, which indicates the performance of the service unit is Good. As a further evaluation for service improvement, three service element values with the lowest values were taken: the system, mechanism, and procedure elements, service time elements, and service product specification elements. The practicum module will be classified based on the difficulty level of the system, mechanism, and procedure. In the service time element, the instructor will start and end the practicum on time, the Zoom admin will act as a time monitor, and students are directed to be present 5 minutes before the practicum. In the service specification product element, untidy practicum modules and unclear PowerPoint visualizations will be improved through synchronization of semester learning plans (RPS) with universities, adjustment of modules according to learning outcomes, standardization of visualization, and instructor training.
Keywords: Internet Reactor Laboratory (IRL), Community Satisfaction Index (CSI), Community Satisfaction Survey (CSS), evaluation of practicum services
Urgensi Kajian Lingkungan Hidup Strategis (KLHS) Tata Ruang Kegiatan Penyimpanan Permanen Mineral Ikutan Radioaktif
Authors:   Pusat Pengkajian Sistem dan Teknologi Pengawasan Instalasi dan Bahan Nuklir, BAPETEN, Jakarta, Imron Imron , Adi Nugroho Tino Sawaldi , Harianto Rahmat Edhi
Published: December 2024

By Presidential Regulation Number 60 of 2019 concerning the National Policy and Strategy for Nuclear and Radiation Safety, BAPETEN has a role in preparing a Strategic Environmental Assessment (KLHS) for national nuclear policies, plans, and programs. One of the KLHS prepared is for storing Radioactive Associated Minerals (MIR). However, because radioactive mixed mineral products are by-products of mineral operations and extraction, with the authority of the Ministry of Energy and Mineral Resources (ESDM), the preparation of the KLHS must be integrated into the regional government KLHS at the time of opening the mining area. This review proposes reasons for the importance of preparing a KLHS to determine the permanent location of MIR. The review research methodology consists of identifying regulations, screening for gaps in obstacles to current infrastructure conditions, and determining recommendations in preparing a KLHS in permanent storage. From the stages of identifying rules, it is known that determining spatial planning is required to prepare a KLHS. The screening gaps in infrastructure conditions show that the regional government still needs to gain knowledge capacity regarding the permanent storage of MIR. The results of this study recommend that BAPETEN can propose guidance and assistance in preparing KLHS to determine the spatial layout of the permanent storage location of MIR. BAPETEN must coordinate with the Ministry of Energy and Mineral Resources and the Ministry of Environment to integrate KLHS for permanent storage spatial layout and identify the contents in the KLHS related to environmental carrying capacity and capacity.
Keywords: Permanent Storage, Strategic Environmental Assessment (KLHS), Spatial KLHS, Radioactive Associated Minerals (MIR)
The Effect of Air Exchange Rate and Room Size on Dose Estimation of Partial Substitution of Tin Slag 2 on Fine Aggregate in Making Mortar in Buildings
Authors:   Directorate of Regulatory Development for Radiation Facilities and Radioactive Sources, Nuclear Energy Regulatory Agency of Indonesia, Yuwana Hermawan Puji
Published: December 2024

Tin slag 2 is a by-product of the tin processing and smelting industry. Tin slag 2 contains radioactive from the uranium and thorium decay series with specific activity concentrations. The current condition of tin slag 2 is still stored in storage. This study aims to simulate using tin slag 2 as a partial substitute for fine aggregate in making mortar, used as a floor or wall plastering material. Dose analysis of the use of mortar–tin slag 2 using RESRAD-BUILD. Several radionuclides were measured in tin slag 2, such as 226Ra 5.72 Bq/gram, 228Th 14.29 Bq/gram, 228Ra 16.59 Bq/gram, and potassium 1.16 Bq/gram. According to the regulations, the activity concentration limit is 1 Bq/gram for the uranium and thorium decay series radionuclide and 10 Bq/g for the potassium. Simulations were performed using RESRAD-BUILD software with scenarios of 2 room sizes against one assumption of the building/air exchange rate. In 2 room size assumptions, namely 4x3x2.5 m and 4x5x2.8 m, the results showed that the larger the room size, the smaller the dose received. Assuming the same building exchange rate, because the sizes used are different, the amount of air exchanged will also be different and affect the dose received by the receptor. The challenge that must be considered is that the air exchange rate is greatly influenced by various factors such as design, ventilation systems, natural or mechanical, environmental conditions, etc.
Keywords: tin, slag 2, partial, substitution, mortar
Repertorio del joven violonchelista. Dificultades orquestales.
Authors: Dobrushkina Viktoriya
Published: December 2024

La presente antología de repertorio orquestal fue elaborada con fines didácticos por los docentes del Instituto Universitario de Bellas Artes (IUBA), integrantes del UCOL-CA-52, para las asignaturas Repertorio Orquestal II, Repertorio Orquestal III correspondientes al Programa Educativo de la Licenciatura en Música. La antología está integrada por fragmentos de las obras más representativas del periodo Clásico que se interpretan con mayor frecuencia. Se han seleccionado los extractos de mayor complejidad técnica e interpretativa que ayudarán al alumno a desarrollar las competencias necesarias para desempeñarse satisfactoriamente como integrante de la sección de violonchelos dentro de una orquesta sinfónica.
Para cada instrumentalista, trabajar en una orquesta de cámara o sinfónica es uno de los más importantes papeles a desempeñar dentro del ámbito del espectro laboral profesional. Este recurso educativo permitirá al alumno aplicar los conocimientos y habilidades adquiridos en la asignatura de Instrumento: afinación, articulación, ritmo, agilidad, digitación, arcadas, dinámica y fraseo. Desarrollará su capacidad de resolver problemas de ejecución de pasajes específicos de manera técnica, estilística e interpretativa, así como su lectura a primera vista.
Gastronomic Tourism in Ajman, UAE: Opportunities and Challenges
Authors: Rana Varinder Singh
Published: December 2024

Gastronomic tourism is emerging as a significant sector in the travel and hospitality industry, particularly in culturally rich regions like Ajman, UAE (Kim & Iwashita, 2016; Wolf, 2002). This paper explores the state of gastronomic tourism in Ajman, examining case studies of local cuisine, food festivals, and contemporary culinary trends (Hall & Mitchell, 2001). It highlights the economic impact, cultural preservation, and challenges facing this growing sector (Smith & Xiao, 2008; Kivela & Crotts, 2006). Through a quantitative analysis involving 400 sampling units segmented by age, gender, marital status, and educational background, the research tests five hypotheses related to the influence of gastronomic tourism on local economies and cultural heritage. Findings indicate that gastronomic tourism can drive economic growth while preserving culinary traditions, but challenges such as infrastructure and quality control must be addressed (Everett & Aitchison, 2008).
Evaluation of Nesting Grounds and Challenges Faced by Olive Ridley (Sea Turtle) During Hatchling in Nagapattinam District Coast, Tamil Nadu
Authors:   Ph.D. Scholar, Department of Geography, Madurai Kamaraj University, Madurai, Tamil Nadu, Mohankumar K , Emayavaramban V
Published: December 2024

The Olive Ridley Sea turtle (Lepidochelys olivacea) is a medium-sized species of sea turtle found in warm and tropical waters, primarily in the Pacific and Indian Oceans. The olive ridley is a small sea turtle, with an adult carapace length averaging 60 to 70 cm. The heart-shaped carapace is characterized by four pairs of pore-bearing inframarginal scutes on the bridge, two pairs of prefrontals, and up to 9 lateral scutes per side. Olive ridleys are unique in that they can have variable and asymmetrical lateral scute counts ranging from five to 9 plates on each side, with six to eight being most commonly observed. Each side of the carapace has 12–14 marginal scutes. In the Indian Ocean, the majority of olive ridleys nest in two or three large groups near Gahirmatha in Odisha, Chennai and Nagappattinam coast in Tamilnadu. In 1991, over 600,000 turtles nested along the coast of Odisha in one week. Nesting occurs elsewhere along the Coromandel Coast and Sri Lanka, but in scattered locations. Nagapattinam district Department of forests collects more than 100,000 eggs every year and established the artificial hatcheries all along the coast. Nagapattinam district forest department formed three Forest Ranges. Sirkazhi, Nagapattinam, Vedaranyam. The entire Nagapattinam district coast line covered these three ranges. They are established temporary artificial hatcheries. The turtle eggs collected all along the coastal line. Nests were found during month end of December to March. After collecting the eggs from the wild, they were buried in the hatchery clutch-wise and their progress was monitored on a daily basis. The normal incubation period of an Olive Ridley egg is 50 - 60 days. The hatchlings were released in the sea soon after they had emerged from their nests.

Keywords: Olive Ridley; Sea Turtle; Hatchling; Nesting; Hatcheries; Nagapattinam