bluuebunny/crossref_metadata_2025 huggingface dataset:
Assessment of the biological effect of Cu nanoparticles impregnated in polyethylene medical devices combined with the effect of LED radiation of the red and violet spectra on the ability of microorganisms to form biofilms and on daily biofilms
Authors: Mishyna M. M. , Hopta O. V. , Syrova G. O. , Avramenko V. L. , Mozgova Y. R. , Malanchuk S. G. , Makarov V. O. , Dubovyk O. S. , Marchenko I. A. , Mishyn Yu. M.
Published: June 2021

For many years scientists around the world have been looking for an alternative to antibiotics due to rapidly growing level of resistance to them. LED light of various spectra and metal nanoparticles are considered as a promising alternative to antibiotics. In this work, we determined the complex effect of copper nanoparticles impregnated in high-pressure polyethylene and non-woven material with the effect of red and violet LED radiation on the ability of microorganisms to form biofilms and on already formed daily biofilms.
Modern approaches of diagnosis and criteria for assessing the limitations of life activities in adolescents with mild mental retardation
Authors: Pidlubnyi V. L. , Chabaniuk S. O.
Published: June 2021

Among the forms of mental pathology that are found in childhood, mental retardation (MR), which makes a significant contribution to the rates of morbidity and disability, occupies a special place. In order to investigate modern approaches and the criteria for diagnosis and assessment of limitations of life with mild MR in adolescents, on the basis of the Kryvyi Rih (Ukraine) neuropsychiatric dispensary, a two-stage clinical-epidemiological, clinical-psychopathological and psychodiagnostic study of 154 people born in 2003-2008 with mild MR was carried out. According to the results of the study, a number of factors that directly affect the quality of life of adolescents with mild MR have been established, among them: underdevelopment of cognitive forms of mental activity (in the forms of violations of logical thinking, slowing down of processes of generalization and comparison), slow pace of thinking and inertia of thought processes (which makes impossible to transfer the skill acquired in the learning process to new conditions), underdevelopment of thinking with a decrease in the function of attention (which leads to underdevelopment of complex emotions and arbitrary forms of behavior), mental underdevelopment in combination with impaired motor skills, speech, memory, attention and emotional sphere.
Comorbid disorders in posttraumatic and post-success epilepsy. Possibilities of therapy
Authors: Kaptalan A. O. , Andreeva T. O. , Stoyanov O. M. , Ostapenko I. O. , Oliinyk S. M.
Published: June 2021

In the article, the authors substantiate the methods of treatment of the most common cause of symptomatic epilepsy in adults, namely traumatic and ischemic. The complexity of treatment is the need to take into account the location and magnitude of brain damage, the severity of the pathological process, risk factors for the most symptomatic epilepsy, the presence of comorbid pathology. Also, the large number of side effects from taking antiepileptic drugs, encourages the discovery of new treatments.A method of treating post-traumatic epilepsy (PTE), in which, in addition to standard anticonvulsant therapy, other drugs were prescribed, such as: ethylmethylhydroxypyridine succinate, nootropic heptapeptide ACTH 4-10, Magnerot, ethylmethylhydroxypyridine succinate, Semax 0.1% solution.Fifteen patients with PTE and 19 patients with post-stroke epilepsy (PIE) were examined. In the process of examination of patients with PTE, the main neurological syndromes that accompany epilepsy are identified and are often combined with each other. At PIE in the anamnesis all patients had various cardiovascular pathology: cerebral atherosclerosis, arterial hypertension, diabetes mellitus, ischemic heart disease, etc.During treatment, in addition to controlling seizures, the number of complaints of cephalgia decreased, the signs of clinical depression and subjective experiences decreased. Positive changes in bioelectrogenesishave been registered. The state of short-term and long-term memory, stability of attention has improved. A positive effect was obtained from the treatment of seizures and comorbid pathology.The alternating effect of the proposed drugs on the background of anticonvulsant therapy leads to a significant reduction in the number and duration of epileptic seizures.
Dynamics of the serum bilirubin level during bile ducts drainage in patients with hilar tumor stenosis and jaundice
Authors: Palytsya R. , Markulan L. , Tsema Ie. , Dubenko D. , Batiuk A. , Susak Ya.
Published: June 2021

Palliative bile duct decompression with various modifications are currently performed in 75-80% of patients with hilar stenosis caused by the tumor. The main goal of palliative care is to reduce the manifestations of jaundice, intoxication, pain syndrome, prolong life period and improve patient’s conditions for chemotherapy.Objective: to evaluate the effectiveness of bile ducts antegrade drainage methods by bilirubin reducing in the palliative treatment of patients with jaundice due to hilar stenosis caused by the tumor.Materials and methods. In a prospective study included 78 patients with hilar obstructive jaundice, who were underwent of palliative antegrade draining of bile ducts: percutaneous transhepatic cholangiostomy (group PTC) - n = 24, externally-internal suprapapillary cholangiostomy (group EISC) - n = 26, percutaneous transhepatic antegrade endobiliary stenting (group PTAES) - n = 28. Endpoints of the study: total serum bilirubin before the procedure, after 3, 7 days and every 10 days for two months. The mean values of bilirubin and the average percentage of decrease in its value at each of the control periods were evaluated in relation to the initial level. Also, at the same time, the cumulative percentage of patients in which bilirubin had a value of ≤34.2 μmol / L (2 mg / dL) or ≤ 85.5 μmol / L (5 mg / dL) was assessed - the threshold values at which a certain type of chemotherapy is possible.Results. In all groups, there was a decrease in the average values of bilirubin levels with an increase in the time passed after the procedure. At all control periods, the mean bilirubin values and the percentage of decrease in the mean bilirubin values did not differ statistically between groups (all p < 0.05). The highest rates of decrease in the level of bilirubin were observed during the first 10 days (about 60.0%). From the 10th to the 60th day, the decrease in the level of bilirubin was approximately 20% from the initial one. The cumulative percentage of patients with the bilirubin level on the 60th day ≤ 34.1 μmol / l (2 mg / dl) was 45.8% in the EISC group, 64.5% in the PTC group, and 63.9% in the PTAES group (p = 0.257) in a month these indicators were 11.7%, respectively; 12.5% and 17.9% (all p <0.05). The decrease in the level of bilirubin ≤ 85.5 μmol / L (5 mg / dL) was more rapid. So, already after 10 days, the cumulative percentage of such patients in the groups exceeded 50.0%: 58.3% in the EISC group, 63.6% in the PTC group, 57.7 % in the PTAES group (p = 0.26) in a month these indicators were respectively 83.3%; 77.3% and 80.8%, after two months, respectively 91.7%, 86.4 and 100% (p = 0.80).Conclusions. The methods of transcutaneous bile ducts drainage/stenting effectively reduce the level of total bilirubin in patients with obstructive jaundice due to hilar stenosis caused by tumor and have no statistically significant differences in the dynamics of bilirubin level within two months of observation.
Professor Myron Korduba’s Contribution Into Geographical Shevchenkiana
Authors: Rudenko Valeriy , Grek Kateryna
Published: June 2021

The article deals with most essential specificities of creative approach and major results of regional geographical studies of Taras Shevchenko, an outstanding Ukrainian poet and painter, disclosed by Myron Korduba (1876 – 1947), Professor, Warsaw University, in his T. Shevchenko as Regional Ethnographer and Archaeologist. It was accentuated that, when studying nature and local people, Taras Shevchenko preferred “a good pencil-drawn sketch from nature”; focused on specific natural phenomena, characteristic for this or that locality; put people and community, their culture and everyday life into a center of his regional geographical cognition.
Gender stereotypes in the information picture of the world (on the example of Ukraine and Poland)
Authors: Khodachuk Yana , Maslova Yuliia
Published: June 2021

The article defines the concept of "gender". Women's gender stereotypes in the Ukrainian and Polish media environments are analyzed. Based on the obtained results, comparisons were made and conclusions were made.
Paramedic-led acute home visiting services in primary care
Authors: Burns John
Published: June 2021

Home visiting is traditionally carried out by GPs but it is becoming increasingly difficult for GPs to do, and many doctors want it removed from their contract. This is opening up a space for the paramedic profession, with paramedics carrying out home visits and designing future primary care services. Paramedics working within primary care can possess the knowledge, leadership and complex skills needed for home visiting, and some are independent prescribers; they can lead acute home visiting services (AHVS). AHVS require effective triage and access to electronic patient records, are underpinned by robust clinical governance and engage in clinical audits. Future primary care paramedic services could include online, video and face-to-face consultations, care home ward rounds, remote triage and home visiting. However, paramedics' contribution to general practice has not been fully evaluated and it may take time for this to become a norm. Regardless, primary care paramedicine has an opportunity to be innovative, shaking off risk-averse protocols for more enlightened practices, and lead the profession.
Photoacoustic computed tomography for functional human brain imaging [Invited]
Authors: Na Shuai , Wang Lihong V.
Published: June 2021

The successes of magnetic resonance imaging and modern optical imaging
of human brain function have stimulated the development of
complementary modalities that offer molecular specificity, fine
spatiotemporal resolution, and sufficient penetration simultaneously.
By virtue of its rich optical contrast, acoustic resolution, and
imaging depth far beyond the optical transport mean free path
(∼1 mm in biological tissues), photoacoustic computed
tomography (PACT) offers a promising complementary modality. In this
article, PACT for functional human brain imaging is reviewed in its
hardware, reconstruction algorithms, in vivo
demonstration, and potential roadmap.
Hemodynamics of the sternocleidomastoid measured with frequency domain near-infrared spectroscopy towards non-invasive monitoring during mechanical ventilation
Authors: Istfan Raeef , Gómez Carlos A. , Applegate Matthew , Rozenberg Dmitry , Reid W. Darlene , Roblyer Darren
Published: June 2021

Mechanical ventilation (MV) is used to assist spontaneous breathing in critically ill patients in the intensive care unit (ICU). MV is a cornerstone of critical care medicine but it is now known that inspiratory muscle dysfunction due to injury, disuse, and/or atrophy during MV plays a major role in outcomes for these patients. For example, prolonged MV is strongly correlated with dysfunction of the sternocleidomastoid (SCM), an accessory inspiratory muscle that has been linked to weaning failure from MV. Hemodynamic monitoring of the SCM may provide an important non-invasive and real-time means to monitor MV. In this work, we first conducted multi-layer Monte Carlo simulations to confirm the ability of near infrared light to detect changes in the oxygenation of the SCM over wide ranges of skin tones and adipose layer thicknesses. We then optimized a custom digital frequency domain near-infrared spectroscopy (FD-NIRS) system for continuous 10 Hz measurements of the SCM at 730 nm and 850 nm. A healthy volunteer study was conducted (N=10); subjects performed sets of isometric neck flexions of the SCM. Substantial changes in oxyhemoglobin + oxymyoglobin (oxy[Hb + Mb]), deoxyhemoglobin + deoxymyoglobin (deoxy[Hb + Mb]), and total hemoglobin + myoglobin (total[Hb + Mb]) were observed during sustained and intermittent isometric flexions. There were notable sex differences observed in the magnitude of hemodynamic changes (∼2x larger changes in males for oxy[Hb + Mb] and deoxy[Hb + Mb]). The magnitude of hemodynamic changes when taking into account µs′ changes during flexions was ∼ 2-2.5x larger as compared to assuming constant scattering (CS), which is a common assumption used for continuous wave (CW) NIRS methods. This study suggests that FD-NIRS provides improved accuracy for hemodynamic monitoring of the SCM compared to CW-NIRS, and that FD-NIRS may provide value for SCM monitoring during MV.
Nanoantenna design for enhanced carrier–envelope-phase sensitivity
Authors: Buckley Drew , Yang Yujia , Yang-Keathley Yugu , Berggren Karl K. , Keathley Phillip D.
Published: June 2021

Optical-field emission from nanostructured solids such as subwavelength
nanoantennas can be leveraged to create sub-femtosecond,
petahertz-scale electronics for optical-field detection. One
application of particular interest is the detection of an incident
optical pulse’s carrier–envelope phase (CEP). Such CEP detection
requires few-cycle, broadband optical excitation where the resonant
properties of the nanoantenna can strongly alter the response of the
near field in time. Little quantitative investigation has been
performed to understand how the geometry and resonant properties of
the antennas should be tuned to enhance the CEP sensitivity and
signal-to-noise ratio. Here we examine how the geometry and resonance
frequency of planar plasmonic nanoantennas can be engineered to
enhance the emitted CEP-sensitive photocurrent when driven by a
few-cycle optical pulse. We find that with the simple addition of
curved sidewalls leading to the apex, and proper tuning of the
resonance wavelength, the net CEP-sensitive current per nanoantenna
can be improved by

5

−

10
×

, and the signal-to-noise-ratio by

50

−

100
×

relative to simple triangular
antennas operated on resonance. Our findings will inform the next
generation of nanoantenna designs for emerging applications in
ultrafast photoelectron metrology and petahertz electronics.
Temporal and spatial error model for estimating the measurement precision of the division of focal plane polarimeters
Authors: Yang Jie , Qiu Su , Jin Weiqi , Xue Fuduo
Published: June 2021

Temporal noise and spatial non-uniformity primarily limit the measurement precision of division of focal plane (DoFP) polarimeters, based on which this study proposes an error model for DoFP polarimeters. The closed-form expressions of the estimation error of the main polarization parameters (Stokes vector, degree of linear polarization, and angle of linear polarization) are derived. Compared with the existing error models for DoFP polarimeters in the presence of temporal noise, the proposed model modifies the normalization condition in traditional calibration methods of DoFP polarimeters and clarifies the selection rule of the coefficient matrix leading to more accurate precision estimation; and experiments using linearly polarized light on a real-world DoFP polarimeter prove its validity.
Photoacoustic laser streaming with non-plasmonic metal ion implantation in transparent substrates
Authors: Ai Xin , Lin Feng , Tong Tian , Chen Di , Yue Shuai , Mohebinia Mohammadjavad , Napagoda Jayahansa , Qiu Yunao , Tong Xin , Yu Peng , Chu Wei-kan , Bao Jiming , Wang Zhiming
Published: June 2021

Photoacoustic laser streaming provides a versatile technique to manipulate liquids and their suspended objects with light. However, only gold was used in the initial demonstrations. In this work, we first demonstrate that laser streaming can be achieved with common non-plasmonic metals such as Fe and W by their ion implantations in transparent substrates. We then investigate the effects of ion dose, substrate material and thickness on the strength and duration of streaming. Finally, we vary laser pulse width, repetition rate and power to understand the observed threshold power for laser streaming. It is found that substrate thickness has a negligible effect on laser streaming down to 0.1 mm, glass and quartz produce much stronger streaming than sapphire because of their smaller thermal conductivity, while quartz exhibits the longest durability than glass and sapphire under the same laser intensity. Compared with Au, Fe and W with higher melting points show a longer lifetime although they require a higher laser intensity to achieve a similar speed of streaming. To generate a continuous laser streaming, the laser must have a minimum pulse repetition rate of 10 Hz and meet the minimum pulse width and energy to generate a transient vapor layer. This vapor layer enhances the generation of ultrasound waves, which are required for observable fluid jets. Principles of laser streaming and temperature simulation are used to explain these observations, and our study paves the way for further materials engineering and device design for strong and durable laser streaming.
Flexible, video-rate, and aberration-compensated axial dual-line scanning imaging with field-of-view jointing and stepped remote focusing
Authors: Jin Rui , Yu Yalan , Shen Dan , Luo Qingming , Gong Hui , Yuan Jing
Published: June 2021

Parallel dual-plane imaging with a large axial interval enables the simultaneous observation of biological structures and activities in different views of interest. However, the inflexibility in adjusting the field-of-view (FOV) positions in three dimensions and optical sectioning effects, as well as the relatively small effective axial range limited by spherical aberration, have hindered the application of parallel dual-plane imaging. Herein, we propose a flexible, video-rate, and defocus-aberration-compensated axial dual-line scanning imaging method. We used a stepped mirror to remotely generate and detect dual axial lines with compensation for spherical aberration and FOV-jointing to rearrange into a head-to-head line for high-speed optical sectioning acquisition. The lateral and axial positions of the two FOVs could be flexibly adjusted before and during imaging, respectively. The method also allows the adjustment of optical sectioning effects according to specific experimental requirements. We experimentally verified the consistent imaging performance over an axial range of 300 μm. We demonstrated high throughput by simultaneously imaging Brownian motions in two

250
 
μm
×
250
  
μm

FOVs with axial and lateral intervals of 150 μm and 240 μm, respectively, at 24.5 Hz. We also showed potential application in functional imaging by simultaneously acquiring neural activities in the optic tectum and hindbrain of a zebrafish brain. The proposed method is, thus, advantageous compared to existing parallel dual-plane imaging and potentially facilitates intravital biological study in large axial range.
Innovationstätigkeit imMittelstand: FuE nicht zwingend erforderlich
Authors: Brink Siegrun , Nielen Sebastian
Published: June 2021

Die vorliegende Studie widmet sich der Innovationstätigkeit des Mittelstandes. Im Fokus stehen dabei nicht-forschende, mittelständischen Innovatoren. Diese meist kleinen Unternehmen sind vorrangig im Dienstleistungsbereich zu finden. Ziel der quantitativen Studie war es zu ermitteln, welche alternativen Strategien nicht-forschende Innovatoren umsetzen, um Innovationen zu generieren und die Frage zu beantworten, inwiefern diese eigene Forschung und Entwicklung ersetzen können. Die Ergebnisse unserer Untersuchung von 331 mittelständischen Unternehmen zeigen, dass der eigenen Forschungs- und Entwicklungstätigkeit für die Erstellung von Produktinnovationen eine entscheidende Rolle zukommt. Dabei nimmt die Relevanz eigener Forschungs- und Entwicklungstätigkeit mit dem Neuigkeitsgrad der Produktinnovation zu. Vor allem radikale Produktinnovationen bedingen eigene Forschungs- und Entwicklungstätigkeit. Prozess- und nicht-technologische Innovationen sind hingegen auch ohne eigene Forschung und Entwicklung realisierbar. Als erfolgreiche Maßnahmen zum Generieren von Innovationen abseits der eigenen Forschung und Entwicklung erweisen sich die Aus- und Weiterbildung der eigenen Belegschaft, sowie Maßnahmen zur Digitalisierung und die allgemeine Investitionstätigkeit.
Agent-based modeling of the central amygdala and pain using cell-type specific physiological parameters
Authors: Miller Neilan Rachael , Majetic Gabrielle , Gil-Silva Mauricio , Adke Anisha P. , Carrasquillo Yarimar , Kolber Benedict J.
Published: June 2021

The amygdala is a brain area involved in emotional regulation and pain. Over the course of the last 20 years, multiple researchers have studied sensory and motor connections within the amygdala in trying to understand the ultimate role of this structure in pain perception and descending control of pain. A number of investigators have been using cell-type specific manipulations to probe the underlying circuitry of the amygdala. As data have accumulated in this research space, we recognized a critical need for a single framework to integrate these data and evaluate emergent system-level responses. In this manuscript, we present an agent-based computational model of two distinct inhibitory neuron populations in the amygdala, those that express protein kinase C delta (PKCδ) and those that express somatostatin (SOM). We utilized a network of neural links to simulate connectivity and the transmission of inhibitory signals between neurons. Type-specific parameters describing the response of these neurons to noxious stimuli were estimated from published physiological and immunological data as well as our own wet-lab experiments. The model outputs an abstract measure of pain, which is calculated in terms of the cumulative pro-nociceptive and anti-nociceptive activity across neurons in both hemispheres of the amygdala. Results demonstrate the ability of the model to produce changes in pain that are consistent with published studies and highlight the importance of several model parameters. In particular, we found that the relative proportion of PKCδ and SOM neurons within each hemisphere is a key parameter in predicting pain and we explored model predictions for three possible values of this parameter. We compared model predictions of pain to data from our earlier behavioral studies and found areas of similarity as well as distinctions between the data sets. These differences, in particular, suggest a number of wet-lab experiments that could be done in the future.
How reliable are self-reported estimates of birth registration completeness? Comparison with vital statistics systems
Authors: Adair Tim , Lopez Alan D.
Published: June 2021

Background

The widely-used estimates of completeness of birth registration collected by Demographic and Health Surveys (DHS) and Multiple Indicator Cluster Surveys (MICS) and published by UNICEF primarily rely on registration status of children as reported by respondents. However, these self-reported estimates may be inaccurate when compared with completeness as assessed from nationally-reported official birth registration statistics, for several reasons, including over-reporting of registration due to concern about penalties for non-registration. This study assesses the concordance of self-reported birth registration and certification completeness with completeness calculated from civil registration and vital statistics (CRVS) systems data for 57 countries.

Methods

Self-reported estimates of birth registration and certification completeness, at ages less than five years and 12–23 months, were compiled and calculated from the UNICEF birth registration database, DHS and MICS. CRVS birth registration completeness was calculated as birth registrations reported by a national authority divided by estimates of live births published in the United Nations (UN) World Population Prospects or the Global Burden of Disease (GBD) Study. Summary measures of concordance were used to compare completeness estimates.

Findings

Birth registration completeness (based on ages less than five years) calculated from self-reported data is higher than that estimated from CRVS data in most of the 57 countries (31 countries according to UN estimated births, average six percentage points (p.p.) higher; 43 countries according to GBD, average eight p.p. higher). For countries with CRVS completeness less than 95%, self-reported completeness was higher in 26 of 28 countries, an average 13 p.p. and median 9–10 p.p. higher. Self-reported completeness is at least 30 p.p. higher than CRVS completeness in three countries. Self-reported birth certification completeness exhibits closer concordance with CRVS completeness. Similar results are found for self-reported completeness at 12–23 months.

Conclusions

These findings suggest that self-reported completeness figures over-estimate completeness when compared with CRVS data, especially at lower levels of completeness, partly due to over-reporting of registration by respondents. Estimates published by UNICEF should be viewed cautiously, especially given their wide usage.
Tick (Acari: Ixodidae) infestation of cuscuses from Maluku Province, Indonesia
Authors: Utami Prasetyarti , Budianto Bambang Heru , Sahara Ana
Published: June 2021

Background and Aim: Cuscuses are one of the endemic Indonesian marsupials, which needs to be protected and revived in terms of the numbers and range of species. Ectoparasites of ticks (Ixodidae) are one potential obstacle to cuscus conservation. Tick infestation can cause blood loss in the host, even being a predisposing factor for infection with pathogenic organisms. This study aimed to determine the prevalence, infestation intensity, and species of ticks present on cuscuses in Maluku Province, Indonesia.

Materials and Methods: Ticks were collected from cuscuses origin of the four regions in Maluku Province, namely the island of Ambon, Seram Island, Romang Island, and Wetar Island . Cuscuses were captured at night, with ticks being collected from them from the head to the tip of the tail. The tick samples obtained from the cuscuses were preserved, identified, and counted. Cuscuses were released back into their habitat after collecting the ticks. The obtained ticks were observed using an Olympus BX51 microscope with an Olympus DP12 digital camera and prepared for examination under a scanning electron microscope (SEM). Infestation rate, infestation intensity, and morphology of the species were described.

Results: The cuscuses were found to be infested with Ixodes cordifer ticks. Cuscuses in Maluku Province had a low tick infestation rate. The range of infestation prevalence of island origin cuscuses in Maluku was between 14.28% and 16.67%. Simultaneously, I. cordifer infestation level was mildly infested based on the intensity of thick infestation ranged from 1 to 1.2 ticks per cuscus. From observation of the tick surface structure under SEM, sexual dimorphism and various specific characteristics of the ticks were identified.

Conclusion: The low infestation rate of I. cordifer ticks in cuscus was influenced by the up and down movement of the conscious activity in the tree, which allowed minimal contact with the ticks. The infestation prevalence rates on each island studied were similar. Such similarities of infestation are related to the similarity of cuscus species among Ambon, Lakor, Seram, and Romang islands, which are all included in the Phalangeridae family, and their similar habitats, behaviors, climatic conditions, and geographical areas.
Dosztojevszkij hatása Gárdonyi kisregényeinek prózaművészetére
Authors: Kovács Gábor
Published: June 2021

Gárdonyi Géza Ki-ki párjával című 1918-as regényének keletkezéséről és forrásairól a Gárdonyi-monográfiák mindegyike ugyanazt ismétli: idézi Gárdonyi József könyvének a megírás körülményeit tárgyaló rövid fejezetét, majd pedig utal az első recenzió felismeréseire. Hatvani Lajos a Nyugat 1923/22. számában megjelent Gárdonyi Géza utolsó regénye című recenziójában a posztumusz kiadott könyvről ezt írta: a „Ki-ki a párjával megállhat Arany és Petőfi legjava termése s megállhat Gottfried Keller falusi Rómeó és Júliája, meg Flaubertnek az egyszerű szívű cselédlányról írott nagy novellája mellett” (Hatvani, 1923). Ezzel a gesztussal Hatvani sajátosan jellemzi Gárdonyi művének irodalomtörténeti kontextusát. Egyfelől nyilvánvalóan jelöli ki azt a századfordulón konzervatívnak tekintett magyar szöveghagyományt (romantika és későromantika), amelyhez odasorolja az írót. Másfelől két világirodalmi összehasonlítási pontot is felajánl: a magyar regényt érdemes Gottfried Keller 1856-ban megjelent Falusi Rómeó és Júlia vagy éppen Flaubert 1877-ben kiadott Egy jámbor lélek című története felől olvasni. Bár mindkét megállapítás tartalmaz részigazságokat, valójában erősen vitatható és nehezen igazolható szövegelemzéssel. Időszerű 100 év után más megközelítést is felvetni. Tanulmányomban amellett érvelek, hogy a Ki-ki párjával legjelentősebb írásművészeti ihletését Dosztojevszkij A félkegyelmű című regényének olvasása nyújtotta.
Dosztojevszkij íráspoétikájához
Authors: Lovizer Lilla
Published: June 2021

A Megalázottak és megszomorítottak című Dosztojevszkij-regényt ma az író kevésbé népszerű művei között szokás számontartani; mintegy a dokumentarista kéziratra épülő-, illetve a sok tekintetben ars poetikus elbeszélés kiforratlan, átmeneti képződményeként. A szakirodalom számára azonban ezzel együtt is az életmű olyan egyedülálló darabja, mely a hatvanas évek elejére beálló alkotói szemléletváltást a maga egészében jeleníti meg.

Ebben a művében Dosztojevszkij nyíltan szembefordul saját negyvenes évekbeli, romantikus múltjával, s kíméletlen karikatúrát fest a „schillerista idealizmus” különféle megnyilvánulási formáiról. Épp emiatt fontos azonban látni azt is, hogy ebben az eljárásban – a regény közismerten összetett irodalmi kódoltsága mellett – legnagyobb segítségére még mindig ugyanaz az E. T. A. Hoffmann szolgál, akit Dosztojevszkij kamaszkora óta szakadatlanul csodált, s akinek legjellemzőbb szövegalkotó technikái eleve is a korai német romantika esztétikai- filozófiai nézeteihez való szkeptikus-ironikus viszonyt tükrözték. Jelen tanulmány kifejezetten a hozzá fűződő intertextuális jelentésképződést vizsgálja, arra a kérdésre keresve választ, hogy miként generálják a különféle Hoffmann-szövegek a regényi szüzsét; mennyiben élnek tovább és/vagy hogyan íródnak át (destruálódnak) Dosztojevszkij művében a tőle származó romantikus minták.
Conceitos Geométricos no primeiro ano escolar: manifestações em livro didático de Sistema de Ensino Desenvolvimental
Authors: Mame Osvaldo Augusto Chissonde , Damazio Ademir
Published: June 2021

O presente trabalho descreve o contexto de organização do ensino em que ocorre o desenvolvimento dos conceitos geométricos no primeiro ano do ensino fundamental. Fundamenta-se na teoria histórico-cultural, em especial as orientações de Davýdov e seus colaboradores. Tem como questão: Como são introduzidos os conceitos geométricos no primeiro ano do ensino fundamental no Sistema Elkonin-Davidov-Repkin? A referência de análise é os livros didáticos do referido ano escolar produzidos pelo grupo de Davýdov e o respectivo livro de orientação aos professores. Prioriza algumas tarefas particulares que introduzem os conceitos com teor geométrico. O estudo revela que as tarefas colocam o pensamento dos estudantes em movimento para as primeiras apropriações teóricas de conceitos geométricos, como ponto, reta e segmento, que expandem para linhas (curvas, quebradas, abertas, fechadas) e comprimento. Há articulação com os componentes da aritmética e da álgebra, mediados pela relação entre grandezas.
A luta por terra e água no quilombo de Acauã no Rio Grande do Norte, Brasil
Authors: Pereira Camila da Silva
Published: June 2021

A invisibilização das comunidades quilombolas por meio de discursos e práticas sociais, políticas e culturais, vem, ao longo de toda a história de luta dessas comunidades, ameaçando a conquista de direitos territoriais, sobretudo o direito à terra. No Brasil, entre 2004 e 2018, sob a alegação da inconstitucionalidade do Decreto 4.887/2003 que regulamenta os procedimentos de titulação da terra, a Ação Direta de Inconstitucionalidade (ADI 3.239/2004) incentivou disputas territoriais e conflitos entre comunidades quilombolas e proprietários de terra, a exemplo da comunidade quilombola Acauã situada no município de Poço Branco no estado do Rio Grande do Norte, Brasil. Este trabalho resulta da pesquisa de doutorado em Geografia pela Universidade Federal do Ceará, Fortaleza, Brasil, encerrada em junho de 2019. Realizamos levantamento bibliográfico, coleta de dados secundários nos sites do Incra e da Fundação Cultural Palmares, registros fotográficos, mapeamento territorial e entrevista semiestruturada com liderança quilombola na comunidade. Os conflitos enfrentados pelos quilombolas de Acauã frente às formas de exploração da terra e diante das estratégias de privá-los de seu direito principal para a sobrevivência, expressam a realidade de muitas outras comunidades quilombolas do Brasil que estão em área de expansão do capital e que embora tenham assegurados legalmente seus direitos, estes não são garantidos em meio às investidas dos agentes capitalistas no espaço e pela burocracia das ações por parte do Estado.
The influence of hofstedeâ€™s cultural dimensions on corporate social responsibility implementation: a study on state-owned companies in Java, Indonesia
Authors: Diamastuti Erlina , Nastiti Tyas Ajeng , Khoirina Marisya Mahdia
Published: June 2021

This study aims to examine the influence of Hofstedeâ€™s cultural dimension on the implementation of Corporate Social Responsibility at State-Owned Companies in Java, Indonesia. The data were analysed using multiple linear regression analysis with the sample consisting of 100 employees at 50 state-owned company in Java, Indonesia taken by using a purposive sampling method and the return rate of the questionnaire is 62%. The results indicate that the five dimensions of Hofstedeâ€™s culture only Power Distance and Individualism/ Collectivism have a positive and significant effect on the implementation of Corporate Social Responsibility by State-Owned Companies in Indonesia, while Uncertainty Avoidance, Masculinity/ Femininity and Long-term/ Short-term Orientation have a negative but not significant effect on the implementation of Corporate Social Responsibility. The results also indicate that not all of Hofstedeâ€™s cultural dimensions affect the implementation of corporate social responsibility to state-owned companies in Java, Indonesia. This research is expected to provide benefits for researchers and the community that culture is one of the factors that can be considered as a component that can influence the implementation of Corporate Social Responsibility.
Regional financial characteristics and public transparency towards frequency of fraud in the local government
Authors: Priatnasari Yeni , Suhardjanto Djoko
Published: June 2021

It has been noted that Corruption in Indonesia today has become a crucial problem that cannot be underestimated. Some news about the occurrence of corruption in the local government is quite concerned. This study aims to look at the influence of both financial characteristics and regional public transparency towards fraud frequency in local governments at the provincial level. This research was carried out by quantitative descriptive method by looking at local government financial report data and reports from ACCH (Anti Corruption Clearing House). This study used secondary data, namely in the form of Indonesia Provincial Governmentâ€™s financial statements and the results of the ACCH report in 2017. The results of this study are expected to provide advice and input in regional financial governance in all the province to be able to reduce frequency fraud in local governments
Evaluation of the effectiveness of surgical methods for the treatment of recurrent lumbar disc herniation: a cohort retrospective study
Authors: Kravtsov M. N. , Kruglov I. A. , Mirzametov S. D. , Seleznev A. S. , Alekseyeva N. P. , Manukovskiy V. A. , Gaidar B. V. , Svistov D. V.
Published: June 2021

Objective.To compare the effectiveness of surgical methods for treating patients with recurrent lumbar disc herniation.

Material and Methods.The sample consisted of 160 patients operated on in 2014–2019 for recurrent lumbar disc herniation by percutaneous endoscopic discectomy (Group 1), microsurgical discectomy (Group 2), single-level transforaminal interbody fusion (Group 3) and single-level total intervertebral disc replacement (Group 4). The effectiveness of surgical treatment was evaluated using the NRS-11, ODI, and MacNab questionnaires.

Results.Assessment of the pain syndrome severity and the vital activity level of patients revealed significant (p < 0.05) differences in favor of total intervertebral disc replacement. Excellent and good outcomes after arthroplasty according to MacNab criteria were noted in all patients in this group. Similar outcomes were reported in 77.5 % (31/40) of patients in the TLIF group, in 75.1 % (24/32) of patients in the percutaneous endoscopic discectomy group and in 72.6 % (45/62) of patients in the microdiscectomy group. The operation time and length of hospital stay were shorter in the endoscopic and microsurgical discectomy groups (p < 0.001). However, the lower incidence of complications and reoperations was observed in groups of posterior interbody fusion and arthroplasty (p > 0.05).

Conclusion.Arthroplasty with the M6-L implant expands the possibilities of surgery for recurrent lumbar disc herniation. Total intervertebral disc replacement and posterior interbody fusion for recurrent lumbar disc herniation are more effective in comparison with decompressive operations, which is reflected in the improvement of clinical treatment outcomes, reduction of perioperative complications and frequency of repeated interventions.
Single- and multistage surgical treatment of patients with degenerative sagittal imbalance
Authors: Baikov E. S. , Peleganchuk A. V. , Sanginov A. J. , Leonova O. N. , Krutko A. V.
Published: June 2021

Objective. To analyze the nearest clinical and radiological results of simultaneous and staged surgical treatment of patients with degenerative sagittal imbalance.

Material and Methods. Retrospective monocentric cohort study included analysis of data from 54 patients who underwent simultaneous combination of surgical methods with obligatory corrective anterior fusion at the L4–L5 or at L4–L5 and L5–S1 levels (Group I, n = 27) or similar surgical intervention though divided into stages with an interval of 5 days or more (Group II, n = 27). A comparison of clinical, radiological, and operational data during inpatient treatment was carried out.

Results. The duration of surgery was 410.93 ± 76.34 minutes in Group I and 594.63 ± 102.61 minutes in Group II (p = 0.000001); the  blood loss was 926.67 ± 378.63 ml versus 1345.19 ± 522.97 ml, respectively (p = 0.001575). Postoperative clinical and radiological parameters did not differ between groups: VAS back (p = 0.248647), VAS leg (p = 0.196140), PT (p = 0.115965), SVA (p = 0.208449), LL (p = 0.023654), LDI (p = 0.931646), PI-LL (p = 0.693045), GAP (p = 0.823504), and restoration of the ideal Russoly type (p = 0.111476). The incidence of perioperative complications in groups was comparable: 17 (62.96 %) in Group I and 15 (55.56 %) in Group II (p = 0.583171). Patients with a high Charlson comorbidity index had a significantly higher incidence of complications (p = 0.023471). The index of surgical invasiveness in Group I had a significant correlation with the total number of complications (r = 0.421332).

Conclusion. Clinical and radiological results and the incidence of complications are comparable between single- and multistage approaches to correct sagittal balance disorders. In staged treatment, the total duration of surgery and the volume of blood loss are significantly higher. With a high Charlson comorbidity index and Mirza surgical invasiveness index, a multistage approach to the treatment of patients with sagittal imbalance is preferred.
Three-dimensionality in vertebral pathology: the horizontal plane is hidden in every scoliotic deformity
Authors: Dubousset J.
Published: June 2021

The main idea of the paper is that any scoliotic deformity of the spine is a deformity primarily occurring in the sagittal plane. Thisstatement is confirmed by anatomical and clinical data, results of the use of imaging techniques, and biomechanical data. The proposed concept significantly affects the solution of strategic and technical problems in the course of both conservative and surgical treatment of patients with scoliosis. It should be realized that scoliotic deformity is a compensatory response within the balance chain to a rotational phenomenon occurring in the frontal plane. The goal of the doctor is to achieve the balance of the patient's body through understanding its three-dimensionality and realizing the importance of taking into account the horizontal plane.
Hubungan Efikasi Diri dengan Kecemasan Menyusun Skripsi pada Mahasiswa Keperawatan
Authors: Saraswati Niken , Dwidiyanti Meidiana , Santoso Agus , Wijayanti Diyan Yuli
Published: June 2021

Introduction: Students who writing their thesis experience difficulties during the COVID-19 pandemic result in anxiety. The feeling can arise due to a low self-efficacy that view difficult experiences as threats and think about the possibility of failure. Previous studies show different relationship between self-efficacy and anxiety thus requires further research particularly in seeking the relationship of self-efficacy and anxiety on thesis’s writing among undergraduate nursing students.Methods: This study was a correlational study with all of undergraduate nursing students who is writing a thesis as the population. Subjects (112 students) were selected by a proportionate stratified random sampling method. Questionnaires used in this study were General Self-Efficacy Scale (GSES) and Zung Self Rating Anxiety Scale (ZSRAS). Data analysis was performed by Pearson Correlation tests.Results: Main results distinguished that there is a negative relationship between self-efficacy and anxiety of undergraduate nursing students who is writing a thesis with r = -0.445 which is indicate that the relationship between two variable is strong enough.Discussion: Students need to make a list of goals to be achieved, so they are encouraged to try to achieve these goals more. Moreover, students can conduct a variety of things to reduce their anxiety.
Pemaknaan Hidup Survivor Kanker Serviks selama Terapi Pengobatan: Literature Review
Authors: Roberto Regina Aprilia , Hidayati Wahyu
Published: June 2021

Introduction: Cervical cancer treatment process proves to make women experiencing emotional distress that brings new problems in life. Women with cervical cancer who undergo treatment suffer affecting all aspects of life that impact on the meaning of life. There is limited literature review regarding life meaning resources and technique used by women with cervical cancer who undergo treatment. The aim of this study is to find out description about the meaningfulness in life of cervical cancer survivor during treatment period based on sources and technique of finding meaning. Methods: This study used literature review method. The literature search engines used are SCOPUS, SINTA and Google Scholar. The inclusion criteria of article were articles in Indonesian or English, containing sources and techniques for finding meaning in abstract, respondents cervical cancer survivor and published from 2011 to 2020.  Results: Eleven articles show the existence of meaning in life build upon sources of meaning in life including creative, experimental, attitudinal, and hopeful values. Moreover, there are techniques in seeking meaning involving self-understanding, positive action, familiarity with relationships, deepening the values of the meaning of life and worship. Conclusion: The beginning of treatment process results feelings of meaningless, but efforts to make sense of life remain. Family support and spirituality were found to be the things that give the most meaning for cervical cancer survivors to survive.
Endocrine and Body Composition Changes Across a Competitive Season in Collegiate Speed-Power Track and Field Athletes
Authors: Mangine Gerald T. , Mangine Gerald T. , Eggerth Andrew , Gough Jeremy , Stratton Matthew T. , Feito Yuri , VanDusseldorp Trisha A.
Published: June 2021

Mangine, GT, Eggerth, A, Gough, J, Stratton, MT, Feito, Y, and VanDusseldorp, TA. Endocrine and body composition changes across a competitive season in collegiate speed-power track and field athletes. J Strength Cond Res 35(8): 2067–2074, 2021—Maintaining lean mass is important for track and field (TF) athletes who compete in speed-power events, but little is known about how lean mass and related hormones might change over an 8- to 10-month collegiate season. Therefore, to monitor changes in free testosterone (T), cortisol (C), and body composition in TF athletes across their entire competitive season, 9 female (20.3 ± 1.2 years, 169 ± 5 cm, and 67.6 ± 8.5 kg) and 7 male (21.1 ± 2.0 years, 181 ± 9 cm, and 77.3 ± 5.9 kg) Division I TF athletes provided resting and fasted blood samples at the onset of their indoor season (baseline), before and on returning from the indoor conference championships (ICCs), at the beginning and end of a heavy midseason training week (HVY), and before leaving for the National Collegiate Athletic Association (NCAA) Championships. Body composition was also assessed at each of these periods using a 4-compartment model. Except for a 20% reduction (p = 0.030) from ICCs to the onset of HVY in men only, linear mixed models with repeated measures did not reveal any changes in hormone concentrations. Compared with baseline, an overall increase in fat-free mass was observed at HVY (∼2.74%, p = 0.023) before it reduced by 3.81% before the NCAA Championships (p = 0.022). Despite variations in training and competition, resting concentrations of hormones indicative of anabolic status remained relatively consistent over the course of an entire season in speed-power TF athletes. Coaches and athletes may consider monitoring these variables to assess the athlete's response to the changing demands of a competitive season.