bluuebunny/crossref_metadata_2025 huggingface dataset:
Silver nanoparticles-integrated terahertz metasurface for enhancing sensor sensitivity
Authors: Mu Tonglin , Ye Yunxia , Dai Zijie , Zhao Rui , Yang Maosheng , Ren Xudong
Published: October 2022

A silver nanoparticles (AgNPs)-integrated terahertz (THz) metasurface sensor was presented and applied to enhance the sensitivity of substance detection. Simulations and experiments were conducted to study the influence of AgNPs on the sensor performance. The enhancement of the local electric field excited by AgNPs can substantially strengthen the interaction between the THz waves and analytes, thereby increasing detection sensitivity. The experimental results indicate that the detection limit of the AgNPs-integrated metasurface sensor is improved by two orders of magnitude compared to that of the bare metasurface sensor without AgNPs. This study provides a convenient method to enhance the sensitivity of THz metasurface sensors.
Concentration fluctuations in growing and dividing cells: Insights into the emergence of concentration homeostasis
Authors: Jia Chen , Singh Abhyudai , Grima Ramon
Published: October 2022

Intracellular reaction rates depend on concentrations and hence their levels are often regulated. However classical models of stochastic gene expression lack a cell size description and cannot be used to predict noise in concentrations. Here, we construct a model of gene product dynamics that includes a description of cell growth, cell division, size-dependent gene expression, gene dosage compensation, and size control mechanisms that can vary with the cell cycle phase. We obtain expressions for the approximate distributions and power spectra of concentration fluctuations which lead to insight into the emergence of concentration homeostasis. We find that (i) the conditions necessary to suppress cell division-induced concentration oscillations are difficult to achieve; (ii) mRNA concentration and number distributions can have different number of modes; (iii) two-layer size control strategies such as sizer-timer or adder-timer are ideal because they maintain constant mean concentrations whilst minimising concentration noise; (iv) accurate concentration homeostasis requires a fine tuning of dosage compensation, replication timing, and size-dependent gene expression; (v) deviations from perfect concentration homeostasis show up as deviations of the concentration distribution from a gamma distribution. Some of these predictions are confirmed using data for E. coli, fission yeast, and budding yeast.
German medical students´ views regarding artificial intelligence in medicine: A cross-sectional survey
Authors: McLennan Stuart , Meyer Andrea , Schreyer Korbinian , Buyx Alena
Published: October 2022

Background

Medical students will likely be most impacted by the envisaged move to artificial intelligence (AI) driven digital medicine, and there is a need to better understand their views regarding the use of AI technology in medicine. This study aimed to explore German medical students´ views about AI in medicine.

Methods

A cross-sectional survey was conducted in October 2019 with all new medical students at the Ludwig Maximilian University of Munich and the Technical University Munich. This represented approximately 10% of all new medical students in Germany.

Results

A total of 844 medical students participated (91.9% response rate). Two thirds (64.4%) did not feel well informed about AI in medicine. Just over a half (57.4%) of students thought that AI has useful applications in medicine, particularly in drug research and development (82.5%), less so for clinical uses. Male students were more likely to agree with advantages of AI, and female participants were more likely to be concerned about disadvantages. The vast majority of students thought that when AI is used in medicine that it is important that there are legal rules regarding liability (97%) and oversight mechanisms (93.7%), that physicians should be consulted prior to implementation (96.8%), that developers should be able to explain to them the details of the algorithm (95.6%), that algorithms should use representative data (93.9%), and that patients should always be informed when AI is used (93.5%).

Conclusions

Medical schools and continuing medical education organisers need to promptly develop programs to ensure that clinicians are able to fully realize the potential of AI technology. It is also important that legal rules and oversight are implemented to ensure that future clinicians are not faced with a workplace where important issues around responsibility are not clearly regulated.
The Simple One-step stool processing method for detection of Pulmonary tuberculosis: A study protocol to assess the robustness, stool storage conditions and sampling strategy for global implementation and scale-up
Authors: de Haas Petra , Yenew Bazezew , Diriba Getu , Amare Misikir , Slyzkyi Andrii , Demissie Yohannes , Sherefdin Bihil , Bedru Ahmed , Mengesha Endale , Dememew Zewdu Gashu , Kebede Abebaw , Getahun Muluwork , Tiemersma Edine , Jerene Degu
Published: October 2022

Background

The Xpert MTB/RIF Ultra (Xpert-Ultra) assay provides timely results with good sensitivity and acceptable specificity with stool specimens in children for bacteriological confirmation of tuberculosis (TB). This study aims to optimize the Simple One-Step (SOS) stool processing method for testing stool specimens using the Xpert-Ultra in children and adults in selected health facilities in Addis Ababa, Ethiopia. The study is designed to assess the robustness of the SOS stool method, to help fine-tune the practical aspects of performing the test and to provide insights in stool storage conditions and sampling strategies before the method can be implemented and scaled in routine settings in Ethiopia as well as globally.

Methods and design

The project “painless optimized diagnosis of TB in Ethiopian children” (PODTEC) will be a cross sectional study where three key experiments will be carried out focusing on 1) sampling strategy to investigate if the Xpert-Ultra M. tuberculosis (MTB) -positivity rate depends on stool consistency, and if sensitivity can be increased by taking more than one stool specimen from the same participant, or doing multiple tests from the same stool specimen, 2) storage conditions to determine how long and at what temperature stool can be stored without losing sensitivity, and 3) optimization of sensitivity and robustness of the SOS stool processing method by varying stool processing steps, stool volume, and storage time and conditions of the stool-sample reagent mixture. Stool specimens will be collected from participants (children and adults) who are either sputum or naso-gastric aspiration (NGA) and/or stool Xpert-Ultra MTB positive depending on the experiment. Stool specimens from these participants, recruited from 22 sites for an ongoing related study, will be utilized for the PODTEC experiments. The sample size is estimated to be 50 participants. We will use EpiData for data entry and Stata for data analysis purposes. The main analyses will include computing the loss or gain in the Xpert-Ultra MTB positivity rate and rates of non-determinate Xpert-Ultra test results per experiment compared to the Xpert-Ultra MTB result of stool processed according to the published standard operating procedures for SOS stool processing. The differences in the MTB positivity rate by regarding testing more than one sample per child, and using different storage, and processing conditions, will be also compared to the baseline (on-site) Xpert-Ultra result.
Raising the bar for patient experience during care transitions in Canada: A repeated cross-sectional survey evaluating a patient-oriented discharge summary at Ontario hospitals
Authors: Okrainec Karen , Chaput Audrey , Rac Valeria E. , Tomlinson George , Matelski John , Robson Mark , Troup Amy , Krahn Murray , Hahn-Goldberg Shoshana
Published: October 2022

Background

Patient experience when transitioning home from hospital is an important quality metric linked to improved patient outcomes. We evaluated the impact of a hospital-based care transition intervention, patient-oriented discharge summary (PODS), on patient experience across Ontario acute care hospitals.

Methods

We used a repeated cross-sectional study design to compare yearly positive (top-box) responses to four questions centered on discharge communication from the Canadian Patient Experience Survey (2016–2020) among three hospital cohorts with various levels of PODS implementation. Generalized Estimating Equations using a binomial likelihood accounting for site level clustering was used to assess continuous linear time trends among cohorts and cohort differences during the post-implementation period. This research had oversight from a public advisory group of patient and caregiver partners from across the province.

Results

512,288 individual responses were included. Compared to non-implementation hospitals, hospitals with full implementation (>50% discharges) reported higher odds for having discussed the help needed when leaving hospital (OR = 1.18, 95% CI = 1.02–1.37) and having received information in writing about what symptoms to look out for (OR = 1.44, 95% = 1.17–1.78) post-implementation. The linear time trend was also significant when comparing hospitals with full versus no implementation for having received information in writing about what symptoms to look out for (OR = 1.05, 95% CI = 1.01–1.09).

Interpretation

PODS implementation was associated with higher odds of positive patient experience, particularly for questions focused on discharge planning. Further efforts should center on discharge management, specifically: understanding of medications and what to do if worried once home.
Physiology of PNS axons relies on glycolytic metabolism in myelinating Schwann cells
Authors: Deck Marie , Van Hameren Gerben , Campbell Graham , Bernard-Marissal Nathalie , Devaux Jérôme , Berthelot Jade , Lattard Alise , Médard Jean-Jacques , Gautier Benoît , Guelfi Sophie , Abbou Scarlette , Quintana Patrice , Chao de la Barca Juan Manuel , Reynier Pascal , Lenaers Guy , Chrast Roman , Tricaud Nicolas
Published: October 2022

While lactate shuttle theory states that glial cells metabolize glucose into lactate to shuttle it to neurons, how glial cells support axonal metabolism and function remains unclear. Lactate production is a common occurrence following anaerobic glycolysis in muscles. However, several other cell types, including some stem cells, activated macrophages and tumor cells, can produce lactate in presence of oxygen and cellular respiration, using Pyruvate Kinase 2 (PKM2) to divert pyruvate to lactate dehydrogenase. We show here that PKM2 is also upregulated in myelinating Schwann cells (mSC) of mature mouse sciatic nerve versus postnatal immature nerve. Deletion of this isoform in PLP-expressing cells in mice leads to a deficit of lactate in mSC and in peripheral nerves. While the structure of myelin sheath was preserved, mutant mice developed a peripheral neuropathy. Peripheral nerve axons of mutant mice failed to maintain lactate homeostasis upon activity, resulting in an impaired production of mitochondrial ATP. Action potential propagation was not altered but axonal mitochondria transport was slowed down, muscle axon terminals retracted and motor neurons displayed cellular stress. Additional reduction of lactate availability through dichloroacetate treatment, which diverts pyruvate to mitochondrial oxidative phosphorylation, further aggravated motor dysfunction in mutant mice. Thus, lactate production through PKM2 enzyme and aerobic glycolysis is essential in mSC for the long-term maintenance of peripheral nerve axon physiology and function.
Colon inflammatory index as a useful prognostic marker after R0 resection in patients with colorectal cancer liver metastasis
Authors: Ishii Mitsutoshi , Tominaga Tetsuro , Nonaka Takashi , Oyama Shosaburo , Moriyama Masaaki , Maruyama Keizaburo , Sawai Terumitsu , Nagayasu Takeshi
Published: October 2022

Background

Although R0 resection for colorectal cancer liver metastasis (CRLM) is a promising treatment with improved prognosis, the recurrence rate is still high. No prognostic markers have been reported after resection of CRLM. In this study, we investigated the association between inflammation-based score and prognosis after R0 resection in patients with CRLM.

Methods

We retrospectively investigated 90 patients who underwent R0 resection for CRLM between 2008 and 2018. We calculated colon inflammatory index (CII) (CII0, low risk; CII1, intermediate risk; and CII2, high risk), modified Glasgow prognostic score, prognostic nutritional index, and CRP-to-albumin ratio; and retrospectively assessed the relationship between these scores, the clinicopathological features, and prognosis.

Results

The median follow-up period was 44 months (range, 2–101 months). Five-year relapse-free survival (RFS) (CII2; 12.5%, CII1; 14.5%, CII0; 42.9%) and 5-year overall survival (OS) (CII2; 32.4%, CII1; 25.4%, CII0; 57.7%) were significantly lower in the high CII groups (CII1–2) compared with the low CII group (CII0) (p = 0.021 and p = 0.006, respectively). CEA level was significantly higher in the high CII group than the low CII group (12.4 vs 7.3, p = 0.004). Multivariate analysis showed CII score as an independent predictor of RFS (hazard ratio 2.128, 95%CI 1.147–3.430, p = 0.015) and OS (hazard ratio 2.639, 95%CI 1.331–5.323, p = 0.005).

Conclusion

CII shows promise as a prognostic marker after R0 liver resection in patients with CRLM.
Comprehensive analysis of different tumor cell-line produced soluble mediators on the differentiation and functional properties of monocyte-derived dendritic cells
Authors: Burai Sára , Kovács Ramóna , Molnár Tamás , Tóth Márta , Szendi-Szatmári Tímea , Jenei Viktória , Bíró-Debreceni Zsuzsanna , Brisco Shlomie , Balázs Margit , Bácsi Attila , Koncz Gábor , Mázló Anett
Published: October 2022

Developing dendritic cells (DCs) from monocytes is a sensitively regulated process. One possible way for cancers to avoid immune recognition and antitumor response is the modulation of DC differentiation. Although several studies are available on the examination of tumor-associated macrophages, a comprehensive analysis focusing on the effects of tumor-formed DCs is not known to date. We provide a comparative analysis of the tumor-edited-monocyte derived DCs differentiated in the presence of adenocarcinomas (MDA, HT29, HeLa)- and primary (WM278, WM983A) or metastatic (WM1617, WM983B) melanomas. The immunomodulatory effect of tumors is mediated at least partly by secreted mediators. We investigated the impact of tumor cell-derived conditioned media on the differentiation of DCs from CD14+ monocytes, sequentially determining the phenotype, cytokine production, phagocytic, and the T cell polarizing capacity of moDCs. We completed our observations by analyzing our data with bioinformatic tools to provide objective correlations between phenotypical and functional properties of different tumor-educated moDCs. The correlation analysis revealed significant differences in the characteristics of adenocarcinomas- or melanomas-edited moDCs. We highlight the functional differences in the properties of moDCs differentiated in the presence of various cancer cell lines. We offer new information and options for the in vitro differentiation protocols of various tumor-conditioned moDCs. Our results confirm that various immunomodulatory properties of different tumor cell lines result in multiple manipulations of DC differentiation.
People with COPD have greater participation restrictions than age-matched older adults without respiratory conditions assessed during the COVID-19 pandemic
Authors: O’Hoski Sachi , Kuspinar Ayse , Wald Joshua , Richardson Julie , Goldstein Roger , Beauchamp Marla K.
Published: October 2022

Background

Participation restriction has detrimental effects for older adults but it is unknown how participation differs for people with chronic obstructive pulmonary disease (COPD) compared to older adults of the same age without respiratory conditions. We compared scores on the Late Life Disability Instrument (LLDI) between people with COPD (study group) and a random sample of older adults (control group).

Methods

Participants with COPD (study group) were recruited from two hospitals in Ontario and age- and sex-matched with a ratio of 1:2 with participants from a random sample of community-dwelling older adults who did not report having respiratory conditions (control group). The study group completed the LLDI prior to the COVID-19 pandemic and the control group completed the LLDI at the end of the first wave of the pandemic. LLDI frequency and limitation scores were compared between groups using Wilcoxon rank-sum tests.

Results

Forty-six study group participants (mean age 74.2 (SD 5.5) years) and 92 control group participants (mean age 74.4 (SD 5.4) years) were included. Fifty-four percent of the participants were female. The majority of the study group had severe COPD (median forced expiratory volume in one second of 34.5 (25th-75th percentile 27.0–56.0) % predicted). LLDI sores were lower for the study group compared to the control group for both the frequency (median difference -5.4 points, p<0.001) and limitation (median difference -7.6 points, p<0.001) domains. The personal subscale demonstrated the largest magnitude of difference between groups (median difference -13.4 points) and the social subscale demonstrated the smallest magnitude of difference (-5.2 points).

Conclusion

People with COPD had greater participation restrictions than a random sample of older adults without ongoing respiratory conditions. The differences seen in participation between the two groups may have been reduced due to temporal confounding from the COVID-19 pandemic. While participation is relevant to all older adults, our results suggest that it is especially important that it be assessed in those with COPD.
Evaluation of right ventricular function during liver transplantation with transesophageal echocardiography
Authors: Gouvêa Glauber , Feiner John , Joshi Sonali , Diaz Rodrigo , Manso Jose Eduardo Ferreira , Assad Alexandra Rezende , Cavalcanti Ismar Lima , Salgado-Filho Marcello Fonseca , Pereira Aline D’Avila , Verçosa Nubia
Published: October 2022

Background

The pathophysiology of advanced liver cirrhosis may induce alterations in the circulatory system that may be challenging for the anesthesiologist to manage intraoperatively, and perioperative cardiovascular events are associated with worse outcomes in cirrhotic patients undergoing liver transplantation. It remains controversial whether right ventricular function is impaired during this procedure. Studies using transesophageal echocardiography for quantitative analysis of the right ventricle remain scarce in this setting, yielding conflicting results. The aim of this study was to perform a quantitative assessment of right ventricular function with two parameters derived from transesophageal echocardiography during liver transplantation.

Methods

Nineteen adult patients of both genders undergoing liver transplantation were evaluated in this observational study. The exclusion criteria were age under 18 or above 65 years old, fulminant hepatic failure, hepatopulmonary syndrome, portopulmonary hypertension, cardiopulmonary disease, and contraindications to the transesophageal echocardiogram. Right ventricular function was assessed at five stages during liver transplantation: baseline, hepatectomy, anhepatic, postreperfusion, and closure by measuring tricuspid annular plane systolic excursion and right ventricular fractional area change obtained with transesophageal echocardiography.

Results

Right ventricular function was found to be normal throughout the procedure. The tricuspid annular plane systolic excursion showed a trend toward a decrease in the anhepatic phase compared to baseline (2.0 ± 0.9 cm vs. 2.4 ± 0.7 cm; P = 0.24) but with full recovery after reperfusion. Right ventricular fractional area change remained nearly constant during all stages studied (minimum: 50% ± 10 at baseline and anhepatic phase; maximum: 56% ± 12 at postreperfusion; P = 0.24).

Conclusions

Right ventricular function was preserved during liver transplantation at the time points evaluated by two quantitative parameters derived from transesophageal echocardiogram.
Relative assessment of cloth mask protection against ballistic droplets: A frugal approach
Authors: Márquez-Alvarez Victor , Amigó-Vega Joaquín , Rivera Aramis , Batista-Leyva Alfo José , Altshuler Ernesto
Published: October 2022

During the COVID-19 pandemic, the relevance of evaluating the effectiveness of face masks–especially those made at home using a variety of materials–has become obvious. However, quantifying mask protection often requires sophisticated equipment. Using a frugal stain technique, here we quantify the “ballistic” droplets reaching a receptor from a jet-emitting source which mimics a coughing, sneezing or talking human–in real life, such droplets may host active SARS-CoV-2 virus able to replicate in the nasopharynx. We demonstrate that materials often used in home-made face masks block most of the droplets. Mimicking situations eventually found in daily life, we also show quantitatively that less liquid carried by ballistic droplets reaches a receptor when a blocking material is deployed near the source than when located near the receptor, which supports the paradigm that your face mask does protect you, but protects others even better than you. Finally, the blocking behavior can be quantitatively explained by a simple mechanical model.
Informal caregivers and assistive technology in Norwegian nursing homes
Authors: Anker-Hansen Camilla , Grøndahl Vigdis Abrahamsen , Helgesen Ann Karin , Fagerli Liv Berit , Rummelhoff Guri , Bååth Carina , Halvorsrud Liv
Published: October 2022

Aim

To explore informal caregivers’ experiences and perspectives concerning assistive technology (AT) in two nursing homes, through the conceptual lens of person-centredness.

Background

The integration and use of AT and a person-centred approach to care are political intentions within healthcare services, both internationally and in Norway. In nursing homes, informal caregivers are often collaborators with the staff, and can be important partners concerning the implementation of AT in a person-centred way. However, there is little knowledge about the informal caregivers’ perspectives on the use of AT in nursing homes, or of whether or how they are included in the integration and use of AT.

Methods

The study had a qualitative design and comprised eleven informal caregivers of residents in two nursing homes in Norway. In-depth interviews were used for data collection. The data were analysed using content analysis. COREQ reporting guidelines were applied to ensure comprehensive reporting.

Results

Emerging themes highlighted the slow-going transition from old to new technology, and how the informal caregivers experienced that AT both promoted and degraded the dignity of their family members. Informal caregivers were positive to the use of technology, but have sparse knowledge and information about ATs in the nursing homes. They express a desire for AT to increase activity and safety, which promotes dignity, quality of life, and quality of the care for their family member. The informal caregivers want their family member to be seen, heard, and to get assistance on their own terms, even with regard to technology.

Conclusion

Before AT can be implemented, informal caregivers need to be informed and listened to and included in the processes. Through their stories, one can form an idea of how important a person-centred approach is to contributing to individually tailored and introduced AT in collaboration with the informal caregivers.
Factors affecting household disaster preparedness in South Korea
Authors: Kim Yujeong , Kim Mi Young
Published: October 2022

This study examines current household disaster preparedness and identifies its predictors in South Korea. A structured online survey was administered to 1,243 participants quota-sampled by age and population from each administrative district. Based on the socio-ecological model, interpersonal factors (general characteristics, prior disaster experience, anxiety, dispositional optimism, perceived disaster risk, and disaster preparedness knowledge), institutional factor (front-line preparedness), community factor (community resilience), public policy factor (governmental preparedness), and household disaster preparedness were measured. The data were analyzed using descriptive statistics, Mann–Whitney U test, Kruskal–Wallis test, Bonferroni test, Pearson’s correlation coefficients, and multiple regression. The predictors of household disaster preparedness were occupation, economic status, prior disaster experience, anxiety, disaster preparedness knowledge, front-line preparedness, and community resilience. The most potent predictor of household disaster preparedness was community resilience. Our finding that community resilience, a community factor, has a greater impact on household disaster preparedness than personal factors calls for programs that promote such resilience. Further, continuous public education and campaigns are needed to increase public awareness of household disaster preparedness and to improve the public’s competency to prepare for potential disasters. This study raises the need for community programs for residents to increase household disaster preparedness knowledge and improve their competencies related to disaster response. This study is significant in highlighting the importance of community factors in improving household disaster preparedness amid the need to prepare for various types of disasters.
Determinants of new participation in sports groups among community-dwelling older adults: Analysis of a prospective cohort from The Otassha Study
Authors: Ejiri Manami , Kawai Hisashi , Fujiwara Yoshinori , Ihara Kazushige , Watanabe Yutaka , Hirano Hirohiko , Kim Hunkyung , Obuchi Shuichi
Published: October 2022

Participation in sports groups has health benefits for older adults, such as preventing functional limitations and social isolation. Encouraging participation in sports groups may be an important means of health promotion in older adults. However, there is insufficient research on the determinants of new participation in sports groups to consider effective interventions to promote participation in these groups. We investigated this using data from a 1-year prospective study. Data were obtained from “The Otassha Study” that assessed a cohort of community-dwelling older adults living in an urban area of Japan. Of 769 older adults who participated in a baseline health survey in 2018, 557 participated in a follow-up survey in 2019. We excluded 184 individuals who already participated in sports groups at baseline and 36 with missing data. Participation in sports groups was defined as that occurring more than once a week. Logistic regression analysis was used to identify the determinants of new participation in sports groups, with sociodemographic factors, lifestyle habits, physical functions, cognitive functions, psychological factors, and social factors as independent variables. Forty-one (12.2%) individuals participated in sports groups at follow-up. In the multiple adjusted logistic regression model, new participation in sports groups was significantly associated with female sex (odds ratio [OR] = 5.57, 95% confidence interval [CI]: 1.61‒19.26), engagement in regular exercise (OR = 2.23, 95%CI: 1.03‒4.84), and having a large social network (OR = 1.12, 95%CI: 1.04‒1.20). Physical functions were not associated with new participation. Determinants of new participation were lifestyle habits and social factors, rather than physical functions. Intervention through social networks may be effective in encouraging new participation in sports groups, which, in turn, may facilitate healthy aging.
Association of childhood trauma, and resilience, with quality of life in patients seeking treatment at a psychiatry outpatient: A cross-sectional study from Nepal
Authors: Dhungana Saraswati , Koirala Rishav , Ojha Saroj Prasad , Thapa Suraj Bahadur
Published: October 2022

Quality of life is defined by the World Health Organization as "Individuals’ perception of their position in life in the context of the culture and value systems in which they live and in relation to their goals, expectations, standards and concerns". It is a comprehensive measure of health outcome after trauma. Childhood maltreatment is a determinant of poor mental health and quality of life. Resilience, however, is supposed to be protective. Our aim is to examine childhood trauma and resilience in patients visiting psychiatry outpatient and investigate their relations with quality of life. A descriptive cross-sectional study was conducted with a hundred patients with trauma and visiting psychiatry outpatient. Standardized tools were applied to explore childhood trauma, resilience, quality of life and clinical diagnoses and trauma categorization. Sociodemographic and relevant clinical information were obtained with a structured proforma. Bivariate followed by multivariate logistic regressions were conducted to explore the relation between childhood trauma, resilience, and quality of life. Poor quality of life was reported in almost one third of the patients. Upper socioeconomic status, emotional neglect during childhood, current depression and low resilience were the determinants of poor quality of life in bivariate analysis. Final models revealed that emotional neglect during childhood and low resilience had independent associations with poor quality of life. Efforts should be made to minimize childhood maltreatment in general; and explore strategies to build resilience suited to the cultural context to improve quality of life.
La actividad pesquera extractiva en la Región de Murcia (España) 1987-2020
Authors: Moreno Muñoz Daniel , Espejo Marín Cayetano , García Marín Ramón
Published: October 2022

La pesca extractiva es una actividad con gran tradición en las zonas litorales de España desde que el ser humano las ha ido ocupando a lo largo de la historia. Desde la incorporación de España a la Comunidad Económica Europea, en 1986, este sector ha vivido transformaciones de gran relevancia. Este estudio tiene como objetivo analizar el sector pesquero de captura en la Región de Murcia desde 1987 hasta la actualidad. Para ello se ha recopilado y tratado la información estadística básica: censo de barcos, trabajadores empleados, o cantidad y valor de la pesca desembarcada. Los resultados reflejan una regresión en el número de embarcaciones y de empleados en el sector, mientras que el volumen y precio de las capturas presentan fluctuaciones interanuales, como consecuencia de la reestructuración de la flota pesquera, y una tendencia al alza del valor de las capturas. Conviene destacar la idoneidad de llevar a cabo análisis similares en otros territorios con el fin de conocer la situación actual de la pesca en España.
celos patológicos en el discurso cinematográfico
Authors: Mañez Arocas Constantino , Cabedo Garcia Vicente Ramon
Published: October 2022

Realizamos una selección de películas sobre los celos patológicos buscando films de calidad, de distinta procedencia y época de realización.
Finalmente analizamos ocho películas procedentes de Estados Unidos (4), México, Italia, Francia y Corea del Sur, de directores muy distintos realizadas desde 1927 a 2005 pero todas ellas nos presentan las características del celoso con sus desencadenantes y reacciones típicas de ansiedad, acoso, vigilancia, persecución, episodios violentos, en ocasiones ideas delirantes y alucinaciones y con un final muchas veces trágico.
La visualización y el análisis de estas películas pueden ser útiles para la docencia en ciencias de la salud pudiendo también ayudar a conocer y prevenir situaciones derivadas de los celos enfermizos.
Cuando los médicos nos volvemos pacientes. A propósito del filme El Doctor (1991)
Authors: Bottasso Oscar
Published: October 2022

El filme retrata la vida de un cardiocirujano seco y egocéntrico abocado más enfermedades que enfermos, quien un buen día deberá experimentar en persona lo nefasto de tal actitud. Una hemoptisis intempestiva llevará al diagnóstico de un tumor maligno de laringe y la ulterior indicación de radioterapia. Esa negación tan frecuente en los pacientes aquí raya en lo inaudito, puesto que como maestro de la medicina no puede ser blanco de intervención. En medio de las largas esperas, marañas burocráticas y la frialdad de la relación médico-paciente, conoce a June, bajo tratamiento por un tumor cerebral con quien establecerá una suerte de coalición ante tan amenazante travesía. A partir de la experiencia como enfermo, el trato para con sus pacientes irá incorporando una auspiciosa cuota de empatía hacia quienes se hallan circunstancialmente abatidos por alguna dolencia. June no sobrevive al tumor, pero él consigue superarlo gracias a la extirpación quirúrgica, mostrándose ahora muy decidido a reorientar su vida profesional y familiar, tras tan doloroso aprendizaje.La historia no ha perdido vigencia. Quien más quien menos, todos sabemos de las desventuras atravesadas por muchos pacientes en su derrotero hacia la recuperación de una salud perdida.
Imágenes de tareas universitarias a través de autobiografías, memorias y otros textos literarios
Authors: Hidalgo-Cantabrana Claudio , Hidalgo Agustín
Published: October 2022

En este trabajo se aportan una serie de ejemplos integrados por fragmentos de textos narrativos tomados de diferentes obras que inciden en el valor de las descripciones y percepciones de diversos autores sobre aspectos educativos seleccionados. Se han utilizado textos memorialísticos, literarios y estudios sobre cuestiones relacionadas con los fines de la universidad. En concreto, se recoge información relacionados con planes de estudios, demografía universitaria, libertad de cátedra, aprendizaje, recuerdos del profesorado o elección de especialidad. Cuando ha sido posible se han invocado circunstancias históricas que pueden haber condicionado el estado actual de la universidad española.
Complex Circles of Partition and the Asymptotic Binary Goldbach Conjecture
Authors: Agama Theophilus , Gensel Berndt
Published: October 2022

In this work, we continue the complex circle of partition development that was started in our foundational study [3]. With regard to commandits embedding circle, we define interior and exterior points. On this foundation, we expand the concept of point density, established in [2], to include complex circles of partition. We propose the idea of a quotient complex circle of partition and investigate some of its features in analogy to the quotient group in group theory. With this notion, we can prove an asymptotic version of the Binary Goldbach Conjecture
Mammalian Pheromones
Authors: O'Mara Kevin
Published: October 2022

Mammalian pheromones are widely accepted but poorly understood. Most studies have used the laboratory mouse but some have studied tigers and lions, both in the wild and in captivity. The lion has emerged as unique insofar as the lion produces pheromones from two sources: the lion mane and the lion marking fluid (spray). The presence of pheromones in lion mane was a relatively recent discovery. In this review of the literature, I have compared the volatile organic compounds found in lion marking fluid and lion mane hair. Based on this comparison I have determined the most likely candidate to represent the pheromone responsible for sexual attraction in the lion. A thorough review of the literature has revealed no similar studies.
Influence of Learning Environment on the Academic Performance of Secondary School Students in Makurdi Metropolis
Authors: Aneke Jude
Published: October 2022

Abstract

School environment has tremendous influence in the quality of teaching students receives and the extent of attention they pay to lesson in school. This implies that schools that fail to provide the necessary learning facilities and create conducive atmosphere for teaching and learning may hardly give the best to their students especially in the area of academic performance. This scenario is one of the reasons for poor academic performance of students in many secondary schools in the study area. The main thrust of this paper is to investigate the influence of learning environment on academic performance of secondary school students in Makurdi metropolis of Benue State. Three research questions guided the study. A descriptive survey design was adopted for the study. The population of this study comprised 2, 090 secondary school students from which 399 were selected randomly from 30 secondary schools in Makurdi. A 15-itemstructured questionnaire developed by the researcher titled the Influence of Learning Environment on the Academic Performance of Students” (ILEAPS) was used for data collection. Mean and standard deviations were used to answer the research questions. The results of the study revealed

adequate provision of infrastructures makes students learn with ease thus bringing about good academic achievement (3.82), poor and inadequate physical facilities, obsolete teaching techniques, overcrowded classrooms leads to poor academic achievement of students (3.67), unattractive school buildings and overcrowded classrooms contributes to poor academic achievement of the students in secondary school (3.60). The study also revealed that what happens outside school also affects learning progress (3.45), students from home that has educational facilities perform greater in school than those whose parent do not (3.43) and

parental occupational status affects students’ academic performance (3.38). The study further revealed that

indiscipline among teachers results to retarding students’ academic performance (3.50) and students who are taught by trained professional teachers perform better than those untrained professional teachers (3.42).The study concludes that learning environment influences the performance of students. Based on the findings, the study recommends that Benue State Government should provide adequate school facilities in secondary schools to enhance teaching and learning processes. The Parent Teacher Association (PTA), philanthropist and other charitable organizations are also implored to compliment the effort of the government to boost academic achievement of secondary school students by contributing to modern learning infrastructures to schools.
APPLICATION OF THE ARCH and MS-ARCH MODELS TO THE

IBEX-35 RETURN SERIES
Authors: Rayo Quesada Manuel
Published: October 2022

In the analysis of financial time series, the Autoregressive models with ConditionalHeteroskedasticity (ARCH) and their generalization, the GARCH models, have beenwidely used, demonstrating their good qualities for modeling the volatilities typical of thistype of series. As an alternative, Switching Markov models have emerged that allow theinclusion of random phenomena as possible structural changes in the mean or varianceprocess. This paper aims to demonstrate the best suitability of these regime-switchingprocesses for modeling the conditional variance of the IBEX-35 Index returns.
Bio prospecting of Riboflavin producing bacteria from different riboflavin enriched food sources
Authors: M Hemalatha  , C Subathra Devi
Published: October 2022

Riboflavin is an essential, water-soluble vitamin (B2) and a component of basic cellular metabolism. The aim of the present study is to isolate and characterize riboflavin producing bacteria from different food sources. Ten different riboflavin enriched food sources were collected from Vellore district. Totally 72 bacterial strains were isolated and cultured on nutrient agar plates. Out of these, 43 strains were identified as riboflavin producers. Isolated bacterial strains HDS27, HDS07, HDS14, HDS18, HDS38 and HDS54 isolated from milk, mushroom, spinach, lamb kidney, beef liver and mackerel fish were found to be potent riboflavin producers. Based on morphological, biochemical and molecular characterization, the potent strains were identified as Lactobacillus plantarum (HDS27), Bacillus cereus (HDS07), Delftia tsuruhatensis (HDS14), Citrobacter freundii (HDS18), Enterobacter cloacae (HDS38) and Bacillus cereus (HDS54). The selected potent isolates HDS27 from milk and HDS07 from mushroom showed a maximum riboflavin production of 3.69 mg/L and 2.9mg/L respectively. The present study explores the riboflavin producing novel bacteria from different food sources. This is the first report that the Enterobacter cloacae isolated from beef liver, Delftia tsuruhatensis from spinach and Citrobacter freundii from lamb kidney has the ability to produce riboflavin. These potent strains could be a better starter for substituting the conventional bacteria for large scale production of riboflavin in industry.
Atmospheric evaporative demand and water deficit on the ecophysiology of Rubber seedlings
Authors: Machado Costa Erilva , Macedo Pezzopane José Eduardo , Dan Tatagiba Sandro , Miranda Teixeira Xavier Talita , De Souza Nóia Júnior Rogério , Daniel Salgado Pifano  , Nair de Carvalho Jullyanna
Published: October 2022

The search for genetic materials resistant to adverse weather conditions has been a major focus in studies on species of economic interest. The objective of the present study was to assess the growth and photosynthesis of rubber seedlings clones under two conditions of atmospheric evaporative demand, characterized by fluctuations in temperature (TEMP) and vapor pressure deficit (VPD), associated to two water regimens. Hevea brasiliensis Muell. Arg (RRIM 600 and FX 3864) clones were assessed in two microclimates, at low (TEMP 21.2 ºC and VPD 0.29 Kpa) and high (TEMP 26.9 ºC and VPD 1.49 Kpa) atmospheric evaporative demand, under two water regimens: water deficit and well-watered.  Water deficit 50% water availability was sufficient to reduce the net CO2 assimilation rate, leaf area and total chlorophyll of the clones studied that impacted growth in both microclimates. The effects of water deficit on growth and net carbon assimilation rate were intensified under high atmospheric evaporative demand. However, when comparing the two clones studied, RRIM 600 showed greater growth and photosynthesis without water restriction. The FX 3864 clone, despite the high CO2 assimilation values under high atmospheric demand and without water restriction, showed a reduced growth. The results of this study form an important basis for the selection of genotypes with the potential to develop in adverse climatic conditions. In this sense, the RRIM 600 genotype is recommended as a promising material that would best adapt under adverse climatic conditions.
pandemia começou quando os brancos chegaram
Authors: Monfort Gislaine Carolina , Mota Juliana Grasiéli Bueno
Published: October 2022

A devastação dos territórios sociobiodiversos propagada pela sociedade moderna colonial /capitalista fundamenta a intensa crise ecológica atual. Com essa premissa, o objetivo deste artigo é apresentar uma análise sobre como o modelo de sociedade moderna e colonial coloca em risco a vida e os direitos territoriais originários dos povos indígenas, mas também a terra comum, o planeta Terra. O artista macuxi, Jaider Esbell, assim como as ñandesy e ñanderu kaiowá e guarani, contribuem significativamente para pensar a destruição e o fim do mundo propagada pelo sistema colonial-capitalista, bem como para pensar os modos de resistência anticoloniais que germinam da luta ancestral dos povos originários. A partir de entrevistas semiestruturadas com companheiros kaiowá e guarani, a maioria por meio de plataformas digitais, documentos construídos pelos conselhos tradicionais e acompanhando a mobilização política, analisamos os processos e práticas autônomas de autodefesa kaiowá e guarani em Mato Grosso do Sul, sobretudo, aquelas fortalecidas no contexto da pandemia da Covid-19 (SARS-CoV-2), como a insurgência das barreiras sanitárias, a qual constituiu umas das formas de cuidado coletivo frente à doença.
Geografia e agroecologia
Authors: Heimbach Samuel da Silva , Almeida Rosemeire Aparecida de
Published: October 2022

Durante o período de pandemia da Covid-19 e do isolamento social, os agricultores do projeto de reforma agrária 20 de Março tiveram que adaptar a forma de comercialização de seus produtos para que fosse possível a continuidade do projeto de extensão Feira Agroecológica, que era realizado presencialmente na Universidade Federal de Mato Grosso do Sul/Campus de Três Lagoas. Em março de 2020, com a suspensão das atividades presencias na Universidade, a estratégia encontrada para manter a comercialização foi o sistema de vendas online e entregas à domicilio. Objetiva-se, portanto, apresentar os caminhos desta ação, analisando como se deu a espacialização do consumo de produtos agroecológicos no tecido urbano de Três Lagoas – MS no período pandêmico.  Apesar da comoção social que marcou este momento sanitário trágico na história do país, os agricultores-assentados, e a equipe do projeto de extensão da UFMS/Campus de Três Lagoas, mantiveram-se ativos na realização de atividades que contribuíram para o êxito da espacialização do consumo urbano e de manutenção da renda dos agricultores, investindo em ações de cunho educativo agroecológico sobre a identidade de consumidor-apoiador, o consumo consciente e a importância da reforma agrária.
 
Palavras-chave: Feira Agroecológica. Covid-19. Espacialização. Consumo Consciente. Reforma Agrária.
Notes from the Editors, October 2022
Authors: Editors -
Published: October 2022

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This year is the fiftieth anniversary of The Limits of Growth, one of the most influential, and also controversial, environmental studies ever written. No other environmental work of the 1970s offered such a direct challenge to the underlying assumptions of capitalist neoclassical growth economics, or was responded to so vehemently by establishment thinkers.
Some Lessons on Planning for the Twenty-First Century from the World's First Socialist Economy
Authors: Veduta Elena
Published: October 2022

The Soviet Union's efforts at centralized economic planning suffered greatly by neglecting to integrate cybernetics into a comprehensive model. Today, this cybernetic approach to economic planning is still blocked. The time has come to implement alternative planning in the form of an automated model that coordinates the activities of all industries and sectors of toward a prosperous and sustainable future.
Aplicação de métodos preditivos em evasão no ensino superior: Uma revisão sistemática da literatura
Authors: Tete Marcelo Ferreira , Sousa Marcos de Moraes , De Santana Talia Santos , Silva Salatyel Fellipe
Published: October 2022

A evasão escolar é considerada um problema complexo que perpassa diversos níveis e dimensões de análise. O desenvolvimento de modelos preditivos tem sido uma resposta mais dinâmica e proativa ao enfrentamento desse problema. O objetivo desta pesquisa foi o de revisar sistematicamente a literatura sobre predição de evasão no ensino superior. O período de análise foi de 2010 a 2020, compreendendo seis bases de dados de artigos científicos e uma amostra de 48 estudos. Os resultados indicam as características metodológicas e contextuais do estado da arte da literatura em predição da evasão universitária, bem como permitem propor uma agenda de pesquisa para estudos posteriores. A amostra de estudos analisados evidenciou a carência de pesquisas que relatem ou proponham ações de gestão e de políticas educacionais para além de aplicação dos modelos preditivos de evasão.