bluuebunny/crossref_metadata_2025 huggingface dataset:
Structural Evolution and Hydrocarbon Accumulation Conditions of the StrikeSlip Pull-Out Basin in the Central African Rift System: A Case Study of the Doseo Basin in Chad
Authors:   China National Oil and Gas Exploration and Development Corporation, Beijing, China, Hong M A , Zhaoming Wang , Lin Wang , Jie H U , Huahua Gao , Yuhua Wang , Simin Gao ,   China National Oil and Gas Exploration and Development Corporation, Beijing, China, Yebo Du , Li Wang , Haiyan Zhou ,   Research Institute of Petroleum Exploration and Development, PetroChina; Beijing, China
Published: February 2025

Doseo Basin is the key block of CNPC's overseas oil and gas exploration currently in Chad, and important oil and
gas discoveries have been made in recent years. Based on the latest drilling and seismic data, utilize geochemical
analysis data, this paper systematically analyzes the tectonic evolution and basic petroleum geological conditions and
hydrocarbon accumulation in the CNPC’s blocks of Doseo Basin, and identifies the next favorable exploration areas.
Three mainly stages of tectonic evolution and three sets of favorable source rocks are mainly developed in Doseo Basin.
The Kedeni Formation source rocks have large thickness, wide distribution, good organic matter type and high maturity,
are the most favorable reservoir formation conditions. The fault system formed by multi-stage tectonic activities provides
convenient channels for oil and gas migration and accumulation. The reservoir formation assemblages are dominated
by lower generated and upper stored assemblages of Kedeni Formation. Many types of structural traps are developed,
such as anticline, fault anticline, fault nose and fault block. The central depression is the main source of hydrocarbons
generation, and hydrocarbons migrated closed vertically and laterally along faults formed structural reservoirs near the
central depression. On the basis of this analysis, the next favorable exploration fields in the study area are defined. The
structure-lithologic reservoirs in the north steep slope zone and the south slope zone, and the oil and gas exploration
in the deep Mangara Formation are mainly the next favorable exploration areas. The research results point out the
direction for the follow-up exploration in the study area, and it is hoped to open a new situation of exploration and
consolidate the resource base for increasing oil and gas storage and production in Doseo Basin.
Profil Pengobatan Infeksi Saluran Napas Atas Akut (ISPA) dan Hubungannya dengan Kunjungan Ulang Pasien
Authors: Sombuk Carl Ray Kalla , Astiarani Yunisa , Kristian Kevin
Published: February 2025

ISPA merupakan salah satu permasalahan yang sering dijumpai di masyarakat. ISPA diakibatkan oleh virus dan bakteri. ISPA menyerang berbagai golongan usia, mulai dari balita, anak, maupun dewasa. Golongan obat antibiotik, kortikosteroid, vitamin, dan obat simptomatik digunakan untuk mengobati ISPA. Timbul permasalahan penggunaan obat yang kurang sesuai sehingga menimbulkan kunjungan ulang pasien untuk berobat lagi pada layanan kesehatan primer. Tujuan penelitian ini untuk mengetahui profil pengobatan ISPA dan hubungannya dengan kunjungan ulang pada pasien ISPA di Klinik A, Kediri, Jawa Timurenggunakan desain penelitian potong lintang dengan pendekatan retrospektif mengguanakan telaah rekam medis. Pengambilan sampelon-random berupa whole population sampling pada penderita ISPA pada periode bulan Januari-Maret 2021 dan jumlah populasi beserta sampel sebesar 127 responden usia > 18 tahun. Menggunakan data rekam medis dan dianalisis menggunakan uji Chi-Square. Sebesar 65,5% usia > 18 tahun, 50,4% obesitas, 14,2% komorbid. Sebesar 20,5% menggunakan antibiotik, 35,4% kortikosteroid, 100% obat simtomatik, dan 52,8% vitamin. Sebesar 17,6% pasien ISPA menggunakan antibiotik, faringitis 26,7%, sinusitis 25%, common cold 15%, dan tonsilofaringitis akut 100%. Sebesar 10,2% melakukan kunjungan ulang 2 dan 6,3% >2. Tidak ada hubungan kunjungan ulang dengan penggunaan kortikosteroid (p=0,201) vitamin (0,162). Dengan uji Fisher-Exact, hasilnya signifikan antara kunjungan ulang dengan penggunaan antibiotik (p=0.014).
Perbandingan Efektifitas Teknik Rebozo Dengan Teknik Birth Ball Terhadap Lama Persalinan Pada Ibu Melahirkan Kala 1 Fase Aktif
Authors: Wahyuni Nur Ismi , Rindiawati Dewi , SR Nurqalbi
Published: February 2025

Data di Indonesia kejadian partus lama menduduki urutan tertinggi di ASEAN yaitu 359 per 100.000 kelahiran hidup ibu meninggal akibat partus lama. Salah satu upaya untuk menangani kala I yaitu dengan menggunakan teknik Rebozo Dengan Teknik Birth Ball. Tujuan penelitian untuk mengetahui Perbandingan Efektifitas Teknik Rebozo Dengan Teknik Birth Ball Terhadap Lama Persalinan Pada Ibu Melahirkan Kala 1 Fase Aktif. Desain penelitian eksperimental menggunakan rancangan posttest only control group design. Penelitian dilaksanakan di KIinik Kehamilan Sehat Pada Bulan Desember 2023, Sampel penelitian yaitu semua ibu Hamil trimester 3 dengan HPL bulan Desember di Klinik Kehamilan Sehat Dengan pembagian sampel 20 ibu kelompok Intervensi dan 20 ibu kelompok kontrol. Teknik pengambilan sampel menggunakan purposive sampling. Instrumen penelitian menggunakan SOP Teknik Rebozo dan Brithing Ball serta Patograf, dan Analisis data menggunakan Uji T-test. Hasil penelitian pada kelompok intervensi yang diberikan Teknik rebozo diperoleh nilai mean 299,55 dengan standar devisiasi 35,528, dan Pada kelompok control yang diberikan Teknik birth ball diperoleh nilai mean 404,55 dengan standar devisiasi 29,409. Hasil uji statistik menunjukan bahwa Ada Perbandingan Efektifitas Teknik Rebozo Dengan Teknik Birth Ball Terhadap Lama Persalinan Pada Ibu Melahirkan Kala 1 Fase Aktif Di Klinik Kehamilan Sehat dengan nilai p-value 0,000. Diharapkan petugas Kesehatan dapat memberikan Teknik rebozo dengan birth ball kepada ibu bersalin untuk mengurangi lama persalinan kala 1 dan sebagai bentuk  meningkatkan mutu pelayanan kebidanan.
Hubungan Status Gizi dengan Kejadian Hipertensi pada Lansia di Indonesia: Systematic Literature Review
Authors: Mukarromah Siti Rizqiyatul , Nadhiroh Siti Rahayu
Published: February 2025

Populasi lansia di Indonesia semakin meningkat, berbagai masalah kesehatan dan penyakit yang menjadi ciri khas lansia pun akan semakin meningkat. Perubahan biologis menyebabkan kecenderungan lansia menderita penyakit degeneratif kronis. Salah satu penyakit degeneratif yang sering terjadi pada lansia adalah hipertensi. Obesitas dapat memicu terjadinya hipertensi karena terganggunya aliran darah. Systematic review ini bertujuan untuk mengulas hubungan antara indeks massa tubuh dengan hipertensi pada lansia. Desain penelitian menggunakan scoping review dengan metode ceklist PRISMA-ScR. Database yang digunakan adalah Google Scholar, ScienceDirect, Willey dan Pubmed. Kriteria yang termasuk pada review ini adalah artikel original, artikel yang diterbitkan dalam Bahasa Inggris dan Bahasa Indonesia, artikel yang membahas tentang status gizi dengan kejadian hipertensi pada lansia di Negara Indonesia dan jurnal terbitan tahun 2019-2023. Seleksi review dankarakterisasi dilakukan dengan penilaian critical appraisal menggunakan Joanna Briggs Instititute (JBI).  Sebanyak 1111 artikel yang berpotensi relevan, 9 artikel yang dapat digunakan Berdasarkan hasil dari 8 artikel menunjukkan bahwa terdapat hubungan antara status gizi dengan hipertensi pada lansia. Kesimpulan pada review ini adalah status gizi menjadi salah satu faktor yang menjadi penyebab terjadinya hiperteni pada lansia sehingga disarankan peneliti selanjutnya melakukan penelitian terkait pencegahan dan penanganan status gizi sehingga dapat meminimalisir terjadinya hipertensi.
Vai trò của nguồn lực và năng lực đối với lợi thế cạnh tranh của trường đại học tư thục trên địa bàn thành phố Hồ Chí Minh
Authors: Nguyễn Hải Quang , Mai Thiện
Published: February 2025

Trước bối cảnh cạnh tranh giữa các trường đại học ngày càng gay gắt, nghiên cứu này xem xét tác động của nguồn lực và năng lực đến lợi thế cạnh tranh trong bối cảnh các trường đại học tư thục trên địa bàn thành phố Hồ Chí Minh. Kết quả đánh giá thang đo và kiểm định giả thuyết từ việc phân tích 564 phiếu khảo sát sinh viên và cựu sinh viên xác nhận rằng các nguồn lực và năng lực đều tác động tích cực đến năng lực khác biệt và lợi thế cạnh tranh. Ngoài tác động trực tiếp đến lợi thế cạnh tranh, năng lực khác biệt còn có vai trò trung gian một phần quan trọng trong tác động của nguồn lực và năng lực đến lợi thế cạnh tranh của các trường đại học tư thục. Sau cùng, dựa trên kết quả nghiên cứu, các hàm ý được đưa ra nhằm nâng cao năng lực cạnh tranh của các trường đại học tư thục.
Enfoque psicopedagógico y pedagógico integral para la enseñanza de lenguas extranjeras y nacionales en la era digital
Authors: Morales-Jaramillo María , Silva-Chávez Judith , Cumbe-Coraizaca Dorys , Real-Ocaña Jenny
Published: February 2025

La enseñanza de lenguas extranjeras y nacionales en la era digital exige un enfoque psicopedagógico y pedagógico integral que aproveche las oportunidades tecnológicas para optimizar el aprendizaje. Este estudio analiza el impacto de las herramientas digitales en la adquisición de competencias lingüísticas, fundamentándose en teorías psicopedagógicas como el constructivismo y la teoría sociocultural de Vygotsky. Se empleó un diseño de investigación cualitativo con un enfoque descriptivo y analítico, utilizando entrevistas a docentes, encuestas a estudiantes y análisis documental. Los resultados evidencian que las plataformas digitales, aplicaciones interactivas y entornos virtuales de inmersión favorecen la participación activa del alumnado, la personalización del aprendizaje y la mejora de la competencia comunicativa. Sin embargo, se identifican desafíos como la falta de formación docente en tecnología educativa y la resistencia al cambio. Se destaca el papel fundamental del profesorado en la mediación del aprendizaje digital y el impacto creciente de la inteligencia artificial en la enseñanza de idiomas. A partir de estos hallazgos, se proponen estrategias para la capacitación docente y la implementación de metodologías innovadoras que integren la tecnología de manera efectiva. Este estudio contribuye al desarrollo de prácticas pedagógicas adaptadas a los retos actuales de la educación lingüística y sugiere líneas de investigación futuras sobre el impacto de la inteligencia artificial en la enseñanza de idiomas.
Una estrategia para el diseño de filtros activos RC de alto orden utilizando algoritmos evolutivos
Authors: Lovay Mónica Andrea , Peretti Gabriela Marta , Romero Eduardo Abel
Published: February 2025

Este trabajo presenta una estrategia modular de diseño para filtros de alto orden implementados en cascada usando algoritmos evolutivos (EAs, Evolutionary Algorithms). El método propuesto evidencia notables ventajas con respecto a los formulados en la literatura para dimensionar este tipo de filtros. Se emplean cuatro EAs del estado del arte: PSO (Particle Swarm Optimization), DE (Differential Evolution), ADE (Average Differential Evolution) y EHO (Elephant Herding Optimization). Como casos de estudio se adoptan dos filtros Chebyshev de décimo orden considerados en trabajos previos. Los resultados muestran que mediante la estrategia propuesta se obtienen configuraciones de filtro con menor error de diseño que otras alternativas, aun empleando componentes de mayor tolerancia. El esfuerzo computacional también resulta ser notablemente más bajo. Una comparación estadística entre los EAs utilizados muestra que DE y ADE son más eficientes en cuanto a la calidad de las configuraciones encontradas.
INTELLIGENT SYSTEM TO DETERMINE THE BEST LECTURER USING ADDITIVE RATIO ASSESSMENT ALGORITHM
Authors: Wahyudi Wahyudi , Satria Budy , Khairi Lutfil
Published: February 2025

The quality of a lecturer's performance is one of the keys to institutional success that must be continuously improved. The performance assessment of lecturers in the Informatics study program of the Faculty of Information Technology, Andalas University faces obstacles in processing quantitative and qualitative data so that it is vulnerable to subjectivity including research productivity, teaching effectiveness, contributions to community service and additional activities. In addition, limitations in a systematic evaluation system result in unfairness and lack of transparency in the decision-making process. The research objective is to create a technology-based approach by applying the Additive Ratio Assessment method based on a Decision Support System. The ARAS method was chosen because it is able to determine effective final results based on multiple criteria that have been determined. The application of the ARAS method consists of 5 stages, namely determining the decision matrix, normalizing the decision matrix, weighting the normalization results, determining the optimum function value and ranking results. The results obtained are alternative data consisting of A1,A2,A3,A4,A5,A6,A7,A8,A9,A10,A11 and 8 criteria and weighting, namely the last education (10%), functional position (15%), certification (20%), number of publications (15%), author order (15%), publication index quality (10%), research grants (10%) and PkM (5%). The ranking results with the highest value in order 1-5 are 0.113875, 0.109785, 0.104235, 0.099005, 0.094715. The final conclusion of this research is that the ARAS method is able to prove the best lecturer assessment to be more efficient, transparent and subjective to be applied in the Andalas University Informatics study program.
Biomasa Karbon Below Ground Paraserianthes Falcataria (L.) Nielsen pada Lahan Agroforestri Tradisional di Distrik Aimas, Sorong
Authors: Ohorella Syarif , Siburian Rima H , Febriadi Ihsan
Published: February 2025

Hutan sebagai bagian dari lingkungan memiliki peranan besar dalam menjaga kestabilan ekosistem. Salah satunya yaitu sebagai penyimpan karbon. Vegetasi berkayu di hutan bisa menjadi pencegah proses lepasnya karbon ke atmosfer melalui proses fotosintesis dimana vegetasi menyerap CO2 kemudian memecahnya dan menyimpannya dalam bentuk biomassa. Hal inilah yang menjadikan hutan penting untuk dikaji kemampuannya dalam menyimpan biomassa dan karbon khusus pada lahan Agroforestri sebagai salah satu unit managemen hutan tingkat tapak. Tujuan dilakukannya riset ini adalah untuk menyusun model persamaan alometrik guna menduga nilai biomasa karbon yang tersimpan pada bagian bawah permukaan tanah (Bellow ground) khusus tegakan pada lahan agroforestri tradisional. Metode yang digunakan adalah destruktif sampling dengan pemilihan pohon sampel secara purposive dan dipilih dua sampel pohon dengan diameter setinggi dada (dbh) yang berbeda namun berumur sama yang mewakili tegakan pada lahan agroforestri di Distrik Aimas Kabupaten Sorong. Selanjutnya di lakukan pengukuran biomassa dan karbon melalui uji laboratorium. Potensi kandungan biomassa total below ground dari 19 tegakan sengon (Paraserianthes falcataria L. Nielsen) yang di peroleh adalah sebesar 0,369  ton/ha. Kandungan karbon below ground tegakan sengon pada lahan agroforestri seluas 2,8  hektar adalah sebesar 0,184  ton C/ha
Harnessing AI in Forensic Audit: Expanding Opportunities for CMAs
Authors: Subramanian Usha Ganapathy , Dasgupta Aditi , Krishnan Ranjith
Published: February 2025

In today’s world, with the rising focus on governance and fraud risk management, forensic audit plays an important role. With its focus on verifying the existence and extent of an alleged fraud or financial misconduct, it differs from regular audits, both in scope and approach. CMAs are well-suited for conducting forensic audits given their knowledge, skillsets and the ability to be impartial and exercise professional judgment. Forensic auditors can augment their procedures with AI tools upping the ante against fraudsters. This article delves deeper into the concept of forensic audit, artificial intelligence (AI), how forensic auditors can leverage AI and how CMAs are well-suited for these engagements.
Role of ‘Digital Footprints’ in Business
Authors: Prasad P. Siva Rama
Published: February 2025

In the modern digital era, business enterprises must establish a digital footprint to maintain relevance, competitiveness and prosperity within the online commercial arena. A digital footprint denotes the existence and visibility of a business enterprise on the internet via diverse online channels and platforms.
One Strategic Product - A Game Changer!
Authors: Jakhotiya Girish
Published: February 2025

This case reveals the close relationship between a strategic product and strategic cost management. A product which proves to be a 'driving engine' of the organization, also acts as a 'game changer' who elevates the fortune of all the stakeholders.
AI-powered Transformative Learning: A Learning Odyssey
Authors: A Spencer Bharath , S Amirthaiyan
Published: February 2025

The advent of AI in education marks a paradigm shift, transforming the learning landscape into a "Learning Odyssey", a journey of intellectual exploration that unlocks transformative learning experiences. AI makes learning more personal, efficient and effective, automating administrative tasks to free up teachers for teaching and facilitating immersive experiences. AI-driven platforms use machine learning, natural language processing and data analytics to create adaptive pathways, real-time feedback, and intelligent tutoring systems. While AI brings benefits like improved student engagement, knowledge retention, and accessibility, it also raises concerns about data privacy, bias, and fairness. As AI advances, it will revolutionize education, making high-quality education more accessible and impactful. Ultimately, it underscores the importance of blending AI's power with a passionate teacher's gentle art of teaching with inspiration and personal touch to unlock true transformative learning.
Reducing Litigation Cost in Corporates Through ADR: Issues and Suggestions
Authors: Ray Subrata Kumar
Published: February 2025

Commercial disputes between parties are inevitable and increasing with complexity of business. However, intelligent, smart and thoughtful strategies can be taken to reduce disputes, if not avoid the disputes. This article suggests a few actions to be taken and a few issues to be addressed to reduce commercial disputes. However, where disputes have already arisen, the logical sequence should be to settle the dispute. The article suggests ways and means of settling such disputes with timelines and seamless means through ADR, which has now been accepted universally as preferred mode of dispute resolution. However, each ADR mode has its advantages and disadvantages. Reducing dispute and early settlement of diffracts shall drastically reduce direct and indirect of the company.
Textile Taxation Transformation: Perspectives from Ahmedabad's Textile Manufacturers and Traders on GST
Authors: Patel Urvish , Jokhi Marzun
Published: February 2025

With the implementation of GST in 2017, the indirect taxation landscape underwent a significant transformation, aiming to streamline tax processes, enhance compliance, and foster a unified national market. For textile manufacturers and traders, this meant simplification and standardization of taxation processes, thereby enhancing ease of doing business and promoting a common national market. This article explores the significance of GST in textile industry, focusing on the perspectives of manufacturers and traders in Ahmedabad, India. Understanding impact of GST on the textile sector is crucial, given its prominence in India's economy and intricate supply chain dynamics. Through surveys and analysis, this study seeks to identify perceptions towards GST among textile manufacturers and traders in Ahmedabad and analyse the relationship between their demographic profiles and GST perceptions. The findings offer insights into how GST has influenced business operations, financial management, and compliance practices within the textile industry, shedding light on opportunities and challenges for stakeholders.
Crafting New Business and Revenue Models by Ambidextrous Blend of Physical and Digital Capabilities
Authors: Basu Paritosh
Published: February 2025

Every business entity and startup's objective, from starting with the digitalisation of operating processes followed by the transformation of business models and revenue models, is to attain sustainable competitive advantages and higher ROI. However, not all such attempts achieve the desired financial impacts and attain operational excellence with DEI. Again, digital technologies are evolving with frequent advancements that require renewed efforts to withstand the disruptive impacts of new developments and sustain competitive advantages. This paper deals with some of the major dimensions of the related success factors that also demand an ambidextrous blend of physical and digital capabilities, if need be, in collaboration with other players. In the end, ten critical points have been listed that may help attain more success with digital transformation. The author would happily collaborate with interested scholars to conduct empirical research studies.
New Wings in Management Accountancy
Authors: Pran Nath Kumar CS
Published: February 2025

In the business arena , particularly of Listed and Unlisted Companies ,the professionals viz Chartered Accountants , Company Secretaries and Cost Accountants have got statutory recognition for employment as whole time employees of the Companies or as financial Auditors, or Cost Auditors or Corporate Auditors , as provided in the Income Tax Act 1961 or Companies Act 1956 (now Act of 2013) , and other government regulations, which are mandatory provisions , but unfortunately , prior to 2013 , no such recognition was given to the Management Accountants. Section 138 of the Companies Act intends to recognise the value of Management Accountants (professionals) by giving rights to management to appoint these professionals at Statutory Position of Internal Auditors. The curriculum of Management accountants is wider than that of others. They are better suited to work as business professionals as they have knowledge of finance and all allied business tributaries/activities. They can work as conduit between the executives of all departments and the management. The advancement of computer and other information technology, touching the borders of Artificial Intelligence, are ready to give him wings to fly higher than other professionals and attain better social and financial status in business world. He would be known as financial wizard, if he grab this golden opportunity to hold double charge as Internal Auditor and Data Analyst. He will be helpful to management in drafting prudent corporate policies , budgets , processes and other forecasts, based on the unbiased data analysis , of historical past performance of the company and other competing business entities.
Automation and AI Adoption – Catalyst to Complement Management Accounting Principles
Authors: Mishra Pranab Kumar
Published: February 2025

The adoption of automation and AI is revolutionizing management accounting by improving efficiency, accuracy, and strategic decision-making. These technologies enable management accountants to add greater value to their organizations by focusing on analysis and strategic planning rather than routine tasks. Despite the challenges, the benefits of integrating automation and AI into management accounting are substantial, making them essential tools for the future of the profession.
Management Accounting and Business Model - An Intertwined Relationship
Authors: Mukherjee Agnishwar
Published: February 2025

In today’s world of cut-throat competition, as the business models are increasingly getting advanced, management accounting is getting advanced too. This is because unless the management can understand what is going on with their business, it will not be able to strategize properly. We can verily compare today’s competition among the businesses to a war between two countries due to very little scope to increase prices. When a business cannot increase prices freely in a market, the obvious way of increasing profit is to reduce the cost and for that the entire value chain of the business model needs to be watched and here comes the importance of the intertwined relationship of management accounting and business model which is discussed in this article using various management accounting tools and their applications.
Management Accounting Tools – An Imperative to Promote Organizational Vision and Strategy
Authors: V. Varun
Published: February 2025

Every company aspires to grow and the growth could be either organic or inorganic. Whichever route a company takes, it follows a growth strategy. C-Level executives who strategize and steer the company towards the organization’s goals should ensure that they take along everybody in the organization’s growth story. And what better tool than a ‘Balanced Score Card’ to achieve this!
In addition to this strategic planning tool, where organizations are combined with another management accounting tool - ‘Activity Based Costing’ in their arsenal, the various stakeholders in an organization are expected to benefit immensely from it.
The purpose of this Article is to provide a succinct overview on these two management accounting tools namely ‘Balanced Score Card’ and ‘Activity based Costing’ and its interplay in promoting an organization’s vision and strategy.
Management Accountants – An Approach to Diversity – Transform Information Through ‘Insight’ to ‘Influence’
Authors: Murty Peri Appala Narasimha
Published: February 2025

Management Accountants with their specialized and advanced knowledge in both Financial and Cost Accounting principles help Top Management in formulating and implementing a Strategy proved to be appropriate for a given problem. For the purpose they collect the relevant data/ information; sources being Financial Accounts (Aggregated in nature) and Cost Accounts (Provide elementwise Costs) along with the Firm’s Cash flows and or Fund flows with due consideration to Segregated Accounts and analyze the information, critically examine with minute details and forms an opinion or Strategy. For this purpose, he may acquire similar Company’s relevant information. The job is more practical than mere theoretical and depends solely on the knowledge, experience and the techniques applied; may vary from time to time and case to case. However, transformation of information ‘through’ ‘insight’ to influence is to be regarded as an approach to Diversity often practiced by Management Accountants.
Banking in Gift City
Authors: Khuntia Manisha
Published: February 2025

The Banking ecosystem is not only the cornerstone of the GIFT IFSC but also one of its most thriving financial services. The IFSCA (Banking) Regulations, 2020 and the IFSCA Banking Handbook lay down the comprehensive principle-based regulatory framework for banking business in GIFT IFSC. This enabling framework is benchmarked with best global standards and practices and has been a game changer in the road map of banking business in GIFT IFSC, resulting in an impressive growth of total banking asset size from $14 bn. in September 2020 to $60 billion in March, 2024. As India is evolving towards its 2047 goal of ‘Viksit Bharat’, IFSCA is determined to develop the GIFT IFSC as an international nerve centre for Banking activity.
Is Arthashastra a Precursor of Competition Economics?
Authors: Majumdar Arnab
Published: February 2025

India has a rich intellectual legacy in the area of economics and finance. Arthashastra that emerged around 4th century BCE is a testimony to this. A proper evaluation of this magnum opus has still not been possible. Of the many unraveled areas of it the one pertaining to competition and related issues is really worth looking at. This article tries to look at it and attempts a comparative analysis with the modern day theories and policies of competition economics.
Logistics Leverage and Evolution in Transportation Infrastructure-perpetual Augmentation of the Expansion of Indian Economy
Authors: Ghosh Avik , Magotra Ankit
Published: February 2025

The logistics sector is an essential component of an economy, having a bidirectional causal relationship with its growth potential. India’s GDP witnessed a significant five-fold growth in the last two decades, of which much can be attributed to the successful policy intervention, infrastructure improvement and perpetual capital formation. This study performs a representative sectoral time-series analysis, establishing the sustainable expansion trajectory of the logistic infrastructure in India. A move towards green and sustainable world-class infrastructure enabled by policy initiatives and increased budget outlays has further strengthened the logistic and transportation sector’s role as a positive transmission channel to economic growth and inclusive development.
From Smart Cities to Green Supply Chains: A New Era of Logistics
Authors: Baskaran T.D.
Published: February 2025

This article explores the convergence of green logistics, smart city infrastructure, and advanced logistics parks as a cornerstone of sustainable urban development. By integrating cutting-edge technologies and environmentally friendly practices, these inter-connected systems can optimize supply chain efficiency, reduce carbon emissions, and enhance overall urban livability. The article delves into specific technological innovations, such as electric vehicles, autonomous transportation, and datadriven logistics, and their role in transforming traditional logistics operations. Furthermore, it examines the potential of logistics parks as sustainable hubs that integrate renewable energy sources, waste management and green building design. The article concludes by highlighting the synergistic relationship between these components and their contribution to creating resilient, eco-friendly, and future-oriented cities.
The New Era of Bullion Trading: Market Reforms through India International Bullion Exchange (IIBX) and Navigating Customs Duty Changes
Authors: Padmanabhan Ramakrishnan
Published: February 2025

The Government of India and the International Financial Services Centres Authority (IFSCA) have undertaken strategic initiatives to establish the India International Bullion Exchange (IIBX), a revolutionary platform set to transform bullion trading in India. With its prefunded model, IIBX provides a strong safeguard against unpredictable duty changes, ensuring enhanced liquidity, transparency, and price discovery. To support IIBX, the Government of India and IFSCA have enabled the participation of qualified jewellers, suppliers, and TRQ holders. As Indian banks begin to engage with IIBX, it may be opportune time for a reassessment of traditional consignment models and move towards more resilient, sustainable and secure bullion trading ecosystem. In a bold move, the Government of India in its Union Budget 2024 slashed the duties on gold and silver from 15% to 6%, sparking both excitement and uncertainty in the bullion market. We explore the sweeping implications of this change, particularly for nominated banks operating on consignment models, who may now face significant financial risks. Discover how the IIBX is set to become a game-changer in the gold and silver market, ensuring stability and fostering a vibrant, transparent marketplace in India's evolving financial landscape.
Fusionistic Convergence of AI to Blockchain TechStack - Turning Opportunities into Realities
Authors: Basu Paritosh
Published: February 2025

Integration of two or more technologies is not a new phenomenon. Robots are created by integrating four technologies collectively called mechatronics and then made intelligent by adding AI tools. However, the fusionistic convergence of the two titans of the digital world, viz., Blockchain and AI, is not a reality in many cases. New opportunities to maximise value creation and minimise value destruction can be created with the collaborative fusion of the two technologies under the strict drive and supervision of the Smart Contract embedded in any blockchain platform's digital systems. The author has tried to ideate and narrate several such probable application use cases that can be experimented to generate more value with a total focus on ESG and DEI. Specific findings, conclusions, and recommendations of research scholars have also been cited in support of the ideated propositions.
Unlocking the Potential of Industrial Engineering in Cost Optimization
Authors: Jayaram R. , Balasubramanian G.
Published: February 2025

Industrial engineering involves application of engineering principles and techniques of scientific management to ensure high levels of productivity at optimum cost in industrial enterprises.
Industrial engineers (IEs) work on productivity improvement and this has to lead to decreased cost at the unit level for activities and in turn for the products that are consumed in these activities. The ultimate proof of productivity improvement is reduced costs reflected in the reported unit cost of products.
IEs must be able to identify and target areas that would yield the greatest in terms of cost savings. They should be able to visualize the consequences of their current action clearly and also check whether it has yielded the desired results in terms of cost savings.
This article outlines the areas for IEs to focus upon to achieve real and permanent reduction of cost.
Corporate Rebuilding Through Demerger: A Case Study Based on Strides Pharma Science Ltd.
Authors: Banerjee Samrat , Rakshit Debdas
Published: February 2025

With the increasing popularity and relevance of sustainability, disclosing the Business Responsibility and Sustainability Report is gradually becoming mandatory for the listed organizations. Therefore, it is necessary to determine whether companies are undertaking the exercise of spin-off to specifically increase their ESG scores. Thus, the impact of spinoff on environmental, social, governance and overall ESG scores have been evaluated for Strides Pharma Science Ltd. Raw ESG data have been collected from Bloomberg database and then analyzed. Findings reveal that the decision of demerger was taken in order to enhance the ESG scores of Strides Pharma Science Ltd. Besides, demerger did not have significant effect on stock returns of Strides Pharma Science Ltd.
Altered functional brain connectivity in Dyt1 knock-in mouse models
Authors: Adury R. Z. , Wilkes B. J. , Girdhar P. , Li Y. , Vaillancourt D. E.
Published: February 2025

DYT1 dystonia is an early onset, generalized form of isolated dystonia characterized by sustained involuntary muscle co-contraction, leading to abnormal movements and postures. It is the most common hereditary form of primary dystonia, caused by a trinucleotide GAG deletion in the DYT1 gene, which encodes the TorsinA protein. Recent studies conceptualized dystonia as a functional network disorder involving basal ganglia, thalamus, cortex and cerebellum. However, how TorsinA dysfunction in specific cell types affects network connectivity and dystonia-related pathophysiology remains unclear. In this study, we aimed to elucidate the impact of the GAG TorsinA mutation present globally and when restricted to the cortical and hippocampal neurons. To accomplish this, we generated two distinct Dyt1 mouse models, one with Dyt1 dGAG knock-in throughout the body (dGAG) and another with a cerebral cortex-specific Dyt1 dGAG knock-in using Emx1 promoter (EMX). In both models, we performed in vivo neuroimaging at ultra-high field (11.1T). We employed functional magnetic resonance imaging (fMRI) to assess resting-state and sensory-evoked brain connectivity and activation, along with diffusion MRI (dMRI) to evaluate microstructural changes. We hypothesized that dGAG mice would exhibit widespread network disruptions compared to the cortex-specific EMX mice, due to broader TorsinA dysfunction across the basal ganglia and cerebellum. We also hypothesized that EMX mice would exhibit altered functional connectivity and activation patterns, supporting the idea that TorsinA dysfunction in the sensorimotor cortex alone can induce network abnormalities. In dGAG animals, we observed significantly lower functional connectivity between key sensorimotor nodes, such as the globus pallidus, somatosensory cortex, thalamus, and cerebellum. EMX mice, while showing less extensive network disruptions, exhibited increased functional connectivity between cerebellum and seeds in the striatum and brainstem. These functional connectivity alterations between nodes in the basal ganglia and the cerebellum in both dGAG, EMX models underscore the involvement of cerebellum in dystonia. No significant structural changes were observed in either model. Overall, these results strengthen the concept of dystonia as a network disorder where multiple nodes across the brain network contribute to pathophysiology, supporting the idea that therapeutic strategies in dystonia may benefit from consideration of network properties across multiple brain regions.
Humanising nanotoxicology: replacement of animal-derived products in the application of integrated approaches to testing and assessment of nanomaterial inhalation hazard
Authors: Fraser Roma , Campbell Keira , Pokorski Pawel , MacKinnon Eve , McAllister Katie , Neves Karla B. , Murphy Fiona
Published: February 2025

Over the past decade, the development of nanomaterials (NMs) has surged, highlighting their potential benefits across multiple industries. However, concerns regarding human and environmental exposure remain significant. Traditional in vivo models for safety assessments are increasingly viewed as unfeasible and unethical due to the diverse forms and biological effects of NMs. This has prompted the design of Novel Approach Methods (NAMs) to streamline risk assessment and predict human hazards without relying on animal testing. A critical aspect of advancing NAMs is the urgent need to replace animal-derived products in assay protocols. Incorporating human or synthetic alternatives can significantly reduce the ethical burden of animal use while enhancing the relevance of toxicity testing. This study evaluates the impact of removing animal-derived products from standard acellular and in vitro assays recommended in a published Integrated Approaches to Testing and Assessment (IATA) for inhaled NMs. We specifically assessed the effects of replacing fetal bovine serum with human platelet lysate in acellular reactivity tests and in vitro toxicity testing using a panel of well-characterized NMs. Significant differences in acellular NM reactivity and dramatic changes in A549 cell growth rates and responses to NMs were observed under different media conditions. Our findings demonstrate that variations in experimental setup can fundamentally impact NM hazard assessment, influencing the interpretation of results within specific assays and across tiered testing strategies. Further investigation is needed to support a shift toward more ethical toxicity testing that does not rely on animal-derived materials.
Advances in regenerative medicine-based approaches for skin regeneration and rejuvenation
Authors: Dutra Alves Nathalia Silva , Reigado Gustavo Roncoli , Santos Mayara , Caldeira Izabela Daniel Sardinha , Hernandes Henrique dos Santos , Freitas-Marchi Bruna Leticia , Zhivov Elina , Chambergo Felipe Santiago , Nunes Viviane Abreu
Published: February 2025

Significant progress has been made in regenerative medicine for skin repair and rejuvenation. This review examines core technologies including stem cell therapy, bioengineered skin substitutes, platelet-rich plasma (PRP), exosome-based therapies, and gene editing techniques like CRISPR. These methods hold promise for treating a range of conditions, from chronic wounds and burns to age-related skin changes and genetic disorders. Challenges remain in optimizing these therapies for broader accessibility and ensuring long-term safety and efficacy.
Axonal regeneration and innervation ratio following supercharged end-to-side nerve transfer
Authors: Harnoncourt Leopold , Schmoll Martin , Festin Christopher , Pflaum Laurenz , Breuss Markus , Klepetko Johanna , Dotzauer Dominik C. , Jaklin Florian J. , Maierhofer Udo , Tratnig-Frankl Philipp , Aszmann Oskar C.
Published: February 2025

Introduction

Peripheral nerve injuries often result in incomplete recovery, particularly after the occurrence of proximal lesions, owing to the extended reinnervation time as well as consequent reductions in the regeneration supportive factors and muscle recovery potential. In these cases, supercharged end-to-side (SETS) nerve transfers preserve the continuity of the original nerves while facilitating additional axonal support to mitigate muscle atrophy. This approach enhances functional recovery and has been demonstrated to be effective in both preclinical models and clinical settings. In this study, a novel SETS nerve transfer model is presented for the upper extremity of the rat to assess the impacts on muscle function, innervation ratio, and motor neuron regeneration as well as investigate the potential to enhance motor function recovery.

Methods

The surgical interventions include transection and end-to-end repair of the musculocutaneous nerve (MCN) in Group A, transfer of the ulnar nerve (UN) to the side of the MCN in Group B, and a combination of both in Group C. The biceps muscle function was assessed 12 weeks post-surgery using electrical stimulation.

Results

Muscle assessments revealed no significant differences in force between the experimental groups. UN-related muscle reinnervation was observed only in Group C after transfer to a regenerating nerve. Retrograde labeling demonstrated motor neuron regeneration of both the MCN and UN in a distal direction toward the muscle; however, tracer uptake of the UN motor neurons following intramuscular tracer application was detected only in Group C. In contrast, stained pseudounipolar cells in the dorsal root ganglia associated with the UN and MCN revealed afferent muscle innervations in Groups B and C.

Discussion

This novel SETS nerve transfer model enables isolated electrophysiological as well as histological evaluations of all nerve sections to determine the muscle innervation ratio exactly. Our findings indicate that substantial functional efferent muscle innervation by the donor nerve is exclusively observed in a regenerating environment.
Efficacy and safety of Saccharomyces boulardii as an adjuvant therapy for the eradication of Helicobacter pylori: a meta-analysis
Authors: Li Manning , Xie Ying
Published: February 2025

Background

Helicobacter pylori (H. pylori) is highly prevalent worldwide and is closely associated with many gastric conditions. Current methods for eradicating H. pylori include triple or quadruple therapy, including antibiotics, proton pump inhibitors, and bismuth agents; however, with antibiotic abuse and increased drug resistance rates, the effectiveness of traditional methods is gradually decreasing, with many adverse effects such as abdominal pain, diarrhea, and intolerance. In recent years, there has been controversy regarding whether adding Saccharomyces boulardii (S. boulardii) to traditional therapies is beneficial for eradicating H. pylori.

Aim

To evaluate the efficacy and safety of S. boulardii as an adjuvant therapy for the eradication of H. pylori.

Methods

We systematically searched the PubMed and Web of Science databases from January 2002 to January 2023. The primary outcome was the H. pylori eradication rate. The secondary outcomes included total adverse effects, abdominal pain, diarrhea, bloating, constipation, nausea, vomiting, taste disorders, and other adverse reactions. We evaluated the included studies for publication bias and heterogeneity. Fixed- and random-effects models were used for studies without and with heterogeneity, respectively, to calculate the risk ratios (RRs) and conduct sensitivity and subgroup analyses.

Results

Nineteen studies comprising 5,036 cases of H. pylori infection were included in this meta-analysis. The addition of S. boulardii to traditional therapy significantly improved the H. pylori eradication rate [RR=1.11, 95% confidence interval (CI): 1.08–1.15] and reduced the incidence of total adverse effects (RR=0.49, 95% CI: 0.37–0.66), diarrhea (RR=0.36, 95% CI: 0.26–0.48), abdominal distension (RR=0.49, 95% CI: 0.33–0.72), constipation (RR=0.38, 95% CI: 0.26–0.57), and nausea (RR=0.50, 95% CI: 0.37–0.68). However, it did not reduce the occurrence of abdominal pain, vomiting, or taste disorders.

Conclusions

S. boulardii supplementation in traditional eradication therapy significantly improves the H. pylori eradication rate and reduces the total adverse effects and incidence of diarrhea, bloating, constipation, and nausea.

Systematic review registration

Prospero, identifier CRD42024549780.
Reconstruction of climatic events from the 16th century in Transylvania: interdisciplinary analysis based on historical sources
Authors: Gaceu Ovidiu Răzvan , Caciora Tudor , Baias Ștefan , Morar Cezar , Dudaș Mihai , Stupariu Marius , Maxim Maria
Published: February 2025

Introduction

Understanding past climate variability is essential for interpreting current and future climate trends, particularly during defining climate periods for the past two millennia, such as the Little Ice Age, which had significant socio-economic impacts.

Methods

The present study uses an interdisciplinary approach, analyzing written documents such as chronicles, diaries, and official records to extract data related to climate events in the 16th century in Transylvania (on the current territory of Romania). The obtained results were processed using statistical techniques to reconstruct the evolution of the weather during the respective period.

Results and discussion

The study identifies multiple pieces of evidence associated with extreme weather events, including 40 unusually warm summers and several years of excess precipitation or drought. In particular, the period 1,527–1544 was marked by intense heat and droughts, severely affecting agriculture and causing famine. In contrast, the second half of the century is defined by increased rainfall, with numerous reports of flooding and excessive rain, particularly in the 1590s. These extreme climatic events profoundly affected society, contributing to food shortages and increased mortality from starvation and diseases (especially the plague). At the same time, compared to the territory of Western Europe, in Transylvania, heat waves and droughts were more frequent in the first half of the 16th century, while in Western Europe, these climatic phenomena were more sporadic and less intense. Finally, the manuscript emphasizes the significant role of the climate in shaping the historical and socio-economic landscape of Transylvania in the 16th century, offering perspectives on the complex interactions between the climate and the human component.