bluuebunny/crossref_metadata_2025 huggingface dataset:
Deteksi Hunian Di Tempat Parkir (Occupancy Detection In Parking Lot)
Authors: Echa Oktamiani Maulana
Published: April 2024

MSIB (Certified Independent Study and Internship) is one of the activity programs at the Merdeka Campus which aims to help students improve their skills and develop themselves. MSIB appointed Orbit Future Academy as one of the partners in the Independent Study program. Founded in 2016 with the aim of improving the quality of life through innovation, education and skills training. In accordance with its mission, namely "We curate and localize international programs and courses for upskilling, re-skilling youth, and the workforce towards jobs of the future". Partners provide opportunities for students to take Artificial Intelligence programs and study online. Learning consists of eight material courses including Python Programming, AI Technology Logic and Concepts, AI Project Cycle, AI Research Methods, ChatGPT, Professional and Company Ethics, Financial Literacy and ending with a Final Project. The final project scope carried out is the Occupancy Detection in Parking Lot project. This project uses the Computer Vision domain with the selection of the YOLO model in detecting objects and pixel segmentation. The project begins with selecting a dataset using roboflow which then goes through data pre-processing for cloning, annotation and augmentation. Then the model is trained using machine learning and deep learning algorithms to understand patterns and characteristics related to parking spaces. Once trained, the AI model will be validated using test data. This aims to ensure that the model truly recognizes the presence of the vehicle. Next, form the application design in creating an informative interface using wireframes. Then enter the deployment stage so that the system can be accessed widely and easily via the web. Lastly, field testing is to find out the performance of the application that has been designed.
Pensando na Paz na América do Sul. Aspectos da violência estrutural nos casos do Brasil, Argentina, Chile e Venezuela
Authors: Winand Érica , Guerra Silvestre Cristiano , Rodrigues Jorge
Published: April 2024

This article’s objective is to explore, in a panoramic perspective, obstacles imposed to the so-called “positive peace” in South-American countries, in light of determining and conditioning factors. Starting with criteria connected to the intersection of strictly economic data — and others related to human development — we chose Brazil, Argentina, Chile and Venezuela for a special analysis, comparing the most important aspects regarding the situation of structural violence in each case, as well as the existence of policies strengthening fertile environments in order to establish a positive relationship between human development and peace
La Criminalidad Organizada, un Severo Problema de Seguridad para el Hemisferio
Authors: Bartolomé Mariano
Published: April 2024

In the international arena that has evolved since the start of this century, organized crime has taken on a predominant role in the security agenda. In the Western Hemisphere this situation has fully come to fruition as demonstrated by the significant impact of illegal drug trafficking and consumption, that has a crosscutting effect on other forms of crime in addition to empowering them. Because of this looming phenomenon with its interconnected activities, organized crime has become an unconventional threat to the security of many nations in the Hemisphere that has in turn affected their societies as well as the citizens that inhabit them. This article describes some of the characteristics of this phenomenon in the Hemisphere, with specific emphasis on Latin America with illegal drug trafficking as it examines other criminal offshoots such as the multiple forms of violence corruption, and the costs that nations of the Hemisphere have had to bear because of this scourge
O Programa de Construção de Submarinos (PROSUB) do Brasil
Authors: Arruda Marcos Aurélio
Published: April 2024

The Brazilian decision to construct a nuclear-powered submarine was the result of the confluence of geopolitical and geostrategic aspects that have been happening since 1960s, and the advantages that the defense investments can bring to the national economy. The difficulty in obtaining naval assets from the US combined with a more independent foreign policy were the forerunners of decisions and actions whose climax were the acquantaince of the uranium cycle and the construction of the nuclear propelled submarine
Reconhecer-se na origem, movimentar-se pelo tempo
Authors: Barbi Ágata
Published: April 2024

Desde o início das produções textuais de Freud sobre sua trajetória clínica, percebemos seu desassossego em relação àquilo que escutava e estudava, mostrando-se atento, inquieto e criativo. No início deste artigo, percorro um brevíssimo passeio pela história da criação da psicanálise, com o intuito de reencontrar as marcas deixadas neste rastro de inquietação em nossa prática hoje. É evidente que a psicanálise foi criada em contexto e cultura diferentes dos que vivemos hoje, especialmente no Brasil, portanto, não é possível simplesmente decalcá-la. Considerando a crítica situação econômica, social e racial que vivemos hoje no Brasil, como sustentar o método psicanalítico sem reproduzir uma lógica individualizante do sofrimento ou sem que opere como forma encobridora do discurso meritocrático neoliberal e, consequentemente, aporofóbico e racista? Como a psicanálise pode avançar em outros territórios, sem que com isso se afaste dos seus fundamentos e se torne uma militância política? Essas inquietações, instigadas principalmente pela minha participação em coletivos de psicanálise, apontaram na direção dos efeitos do trabalho coletivo como potência de transformação social e da própria psicanálise. A partir de Freud, Laplanche, Danto e alguns outros, faço um percorrido pela história e relevância das clínicas públicas, suas diferenças com a clínica privada e, com isso, uma reflexão sobre a posição e o desejo do analista. Como proposta de caminho possível para as perguntas acima, apoio minha argumentação nas noções de dissidência cívica e obrigação ética de Frèdèric Gros e também na perspectiva ética de pensamento e na noção de micropolítica ativa de Suely Rolnik.
Divã
Authors: Gallo de Moraes Eurema
Published: April 2024

Por que o divã? Perspectivas de escuta e a poética da psicanálise é uma leitura relevante visto que oferece um material consistente ao debate acerca deste tema tão frequente nas instituições psicanalíticas, nos espaços de supervisão e nas interrogações pessoais do analista. Lucas consegue escrever um texto preciso e sem rasuras ao mesmo tempo que deixa o leitor confortável para alimentar sua própria reflexão, para pensar sobre sua prática de psicanalisar, ou simplesmente ter a curiosidade em descobrir algo singular.
sujeito em constituição e o traumático
Authors: Dornelles Hoff Fernanda
Published: April 2024

Os acontecimentos traumáticos da cultura em que estamos inseridos fazem rasgos importantes nas tramitações dos encontros entre o sujeito do porvir e os cuidadores amorosos. O trabalho a seguir se dispõe a um estudo sobre os movimentos constitutivos do sujeito e a teoria do trauma, tendo como dispositivo a violência às escolas, ocorrências que ferem o pacto humano do amparo de uns aos outros e da preservação da vida. A partir dos enlaces entre a teoria e os acontecimentos traumáticos, propomos uma reflexão sobre os movimentos pulsionais e estruturais do sujeito psíquico.
violência da estupidez e a estupidez da violência
Authors: Mendes Dias Mauro
Published: April 2024

O objetivo do texto é mostrar uma modalidade de violência que se estrutura como efeito do discurso da estupidez, baseado nas crenças que adulteram a função da verdade em sua relação com o desejo inconsciente e o gozo. Entretanto, faz-se necessário admitir uma impossibilidade de eliminação da violência, na medida em que não existem meios de garantir a sustentação do sujeito pelas palavras de forma inabalável. Tais condições levam a articular tratamentos possíveis de tais limitações.
CHORVACHILIK TARMOG‘IDA KICHIK TADBIRKORLIKNI RIVOJLANTIRISHDA XORIJIY TAJRIBALARDAN FOYDALANISH
Authors: Eshqulova Hilola
Published: April 2024

Sayyoramizda aholi soni shiddat bilan o‘sib borayotgan bir vaqtda insonlar oziq – ovqat mahsulotlariga bo‘lgan talabi tobora ortib bormoqda. Ko‘plab boshqa birlamchi iste’mol mahsulotlari kabi sut ishlab chiqarish va sutchilik tarmog‘ini rivojlantirish ham bugungi kunda har bir mamlakatda muhim ahamiyat kasb etadi. Biz ushbu maqolamizda sut chorvachiligi va unda tadbirkorlikni rivojlantirishda xorij tajribalaridan samarali foydalanish to‘g‘risida fikr yuritdik. Bunda aynan sut chorvachiligida kichik tadbirkorlikni rivojlantirishning o‘rni mamlakatimiz uchun ahamiyatlidir. Sababi mamlakatimizda yetishtiriladigan sutning 90 % atrofidagi ulushi dehqon va tomorqa xo‘jaliklari ulushiga to‘g‘ri keladi.
O‘ZBEKISTONDA CHORVACHILIK MAHSULOTLARINI ISHLAB CHIQARISH HOLATI TAHLILI
Authors: Ruziyeva Dilobar , Xaydarova Sitora
Published: April 2024

Ushbu maqolada chorvachilik mahsulotlarini ishlab chiqarish, qishloq xo‘jaligida mamlakat miqyosida mavjud bo‘lgan chorva mollari va iste’mol mahsulotlari, ulardan olinayotgan sut, go‘sht mahsulotlarining viloyatlar bo‘yicha tahlili keltirilgan. Raqamli texnologiyalar davrida chorva mahsulotlarini ishlab chiqarishni rivojlantirish respublika iqtisodiyotida makro va mikroiqtisodiy ko‘rsatkichlarga ijobiy ta’siri ko‘rsatilgan.
XALQARO MEHNAT MIGRATSIYASIDA YUQORI MALAKALI MUTAXASSISLARNI TASNIFLASH TENDENSIYALARI
Authors: Habibullayev Komiljon
Published: April 2024

Ushbu maqolada olimlarning ilmiy tadqiqotlari va tahlillari natijasida yuqori malakali migrantlarga berilgan ta’riflari muhokama qilingan. Nazariy va iqtisodiy-siyosiy amaliyotda yuqori malaka va mahoratni aniqlash muammolariga ahamiyat qaratildi.
XUSUSIY SEKTORDАGI TАDBIRKORLIK FАOLIYATIGА BERILАYOTGАN IMKONIYATLАRDАN SАMАRАLI FOYDАLАNISH
Authors: Inobatov Abror
Published: April 2024

Bozor iqtisodiyoti erkin tadbirkorlikka, sohibkorlikka asoslangan iqtisodiyotdir. Shuning uchun ham xususiy sektorda tadbirkorlik faoliyatining shakllanishi va rivojlanishi uchun iqtisodiyotda tadbirkorlik muhitini yaxshilashga hamda shu orqali iqtisodiyot tarmoqlarini yanada daromadligini oshirish, aholini ish bilan bandligini yaxshilash, farovonligini yuksaltirishga erishishdir. Bunday ustuvor natijalarga erishishda mamlakatimizda amalga oshirilayotgan iqtisodiy islohotlar xususiy sektorda tadbirkorlikning rivojlanishiga hamda shu asosda, iqtisodiy o‘sishga va milliy iqtisodiyotni barqaror rivojlanishini ta’minlashga qaratilgandir.
СОВЕРШЕНСТВОВАНИЕ МЕТОДОЛОГИИ УПРАВЛЕНЧЕСКОГО УЧЕТА КОМПАНИЙ ЭНЕРГЕТИЧЕСКОЙ ОТРАСЛИ УЗБЕКИСТАНА ДЛЯ ПОВЫШЕНИЯ ЭФФЕКТИВНОСТИ ИХ ФИНАНСОВОГО МЕНЕДЖМЕНТА
Authors: Глазова Марина
Published: April 2024

Статья посвящена определению путей совершенствования методологии управленческого учета компаний энергетической отрасли Узбекистана для повышения эффективности их финансового менеджмента. Для этого проводится регрессионный анализ зависимости доступности и качества предоставляемых электроэнергетических ресурсов в Узбекистане от выделенных в литературном обзоре факторов на основе статистики Всемирного банка за 2003-2020 гг. В результате выявлены ключевые области управленческого учета компаний энергетической отрасли Узбекистана, которые оказывают наибольшее позитивное влияние на эффективность их финансового менеджмента. С учетом выявленных областей предложены авторские рекомендации для совершенствования методологии управленческого учета компаний энергетической отрасли в Узбекистане для повышения эффективности их финансового менеджмента.
АҲОЛИ ОМОНАТЛАРИНИ ТИЖОРАТ БАНКЛАРИГА ЖАЛБ ҚИЛИШНИНГ ДОЛЗАРБ МАСАЛАЛАРИ
Authors: Ибодуллаев Шоҳбоз
Published: April 2024

Дунё банк амалиётида, шу жумладан, Ўзбекистон банк амалиётида депозитлар тижорат банклари мажбуриятларининг асосий турларидан бири ҳисобланади. Шу сабабли, банкларнинг депозит базасининг барқарорлигини таъминлаш уларнинг ликвидлилиги ва молиявий барқарорлигини таъминлашнинг зарурий шартларидан бири ҳисобланади. Мақолада республикамиз тижорат банкларига депозитлар ва омонатлар жалб қилиш билан боғлиқ бўлган долзарб муаммолар аниқланган ва уларни ҳал қилишга қаратилган илмий таклифлар ишлаб чиқилган.
ЭЛЕКТРОН ТИЖОРАТНИ СОЛИҚҚА ТОРТИШНИНГ НАЗАРИЙ АСОСЛАРИ
Authors: Исаев Фахриддин , Камилова Санобар
Published: April 2024

Ушбу мақола электрон тижоратни солиққа тортишнинг назарий асосларига бағишланган бўлиб, кўплаб иқтисочи олимларнинг мавзу доирасида адабиёталри таҳлил қилинган. Электрон тижоратни солиққа тортиш эволюцияси кўриб чиқилган, бугунги кундаги асосий муаммолар очиб берилган ва мавзу якунида хулосалар шакллантирилган.
ФОЙДА СОЛИҒИ БУХГАЛТЕРИЯ ҲИСОБИНИ МОЛИЯВИЙ ҲИСОБОТНИНГ ХАЛҚАРО СТАНДАРТЛАРИ АСОСИДА ТАКОМИЛЛАШТИРИШ
Authors: Курбанов Зият
Published: April 2024

Ушбу мақолада фойда солиғи бухгалтерия ҳисобини молиявий ҳисоботнинг халқаро стандартлари асосида такомиллаштириш масалалари ёритилган. Шунингдек, фойда солиғининг бухгалтерия ҳисоби амалий маълумотлар асосида келтирилган.
РАҚАМЛИ ПАРАМЕТРЛАРНИ МАКРОИҚТИСОДИЙ КЎРСАТКИЧЛАРГА ТАЪСИРИ ҲОРИЖИЙ МАМЛАКАТЛАР МИСОЛИДА
Authors: Махмудов Самариддин
Published: April 2024

Мақолада ҳорижий мамлакатларида, рақамли параметрларнинг макроиқтисодий кўрсаткичларга таъсирини таҳлилининг мураккаб муносабатларни илғор эконометрик моделлардан фойдаланган ҳолда инновацион тадқиқот олиб борилди. Ҳорижий мамлакатларнинг ЯИМ аҳоли жон бошига рақамли параметрларнинг таъсири таҳлил қилинди ҳамда Жаҳон Банкининг (https://data.worldbank.org/) маълумотларининг 21 йиллик кўрсаткичларидан фойдаланилди. Тадқиқот бўйича маълумотлар кўп омилли вақтли қаторлар асосида шакллантирилганлиги учун эконометрик тенгламалар авторегрессив тақсимланган кечикиш ARDL (Autoregressive distributed lag) моделидан фойдаланган ҳолда ишлаб чиқилди. Тадқиқот натижалари шуни кўрсатдики, ушбу минтақаларда рақамли параметрлар макроиқтисодий кўрсаткичларга тўғридан-тўғи ижобий корррелацияни кўрсатган ҳолда муҳим таъсирини намойиш қилди.
ЖИНОИЙ ФАОЛИЯТДАН ОЛИНГАН ДАРОМАДЛАРНИ ЛЕГАЛЛАШТИРИШГА ҚАРШИ КУРАШИШДА БАНК ФАОЛИЯТИНИНГ ХУҚУҚИЙ ЖИХАТЛАРИ
Authors: Омонтошев Мираббосбек
Published: April 2024

Мамлакатимизда жиноий йўл орқали олинган даромадларни легаллаштиришга қарши курашишда банклар фаолиятини такомиллаштириш ва тадқиқ қилиш долзарб масала ҳисобланади. Мазкур мақолада банк тизими орқали жиноий йўл билан олинган даромадларни легаллаштиришнинг назарий, иқтисодий-хуқуқий жихатлари ўрганилган
РОССИЯДА НОГИРОНЛАР УЧУН ИШ ЎРИНЛАРИНИ ЗАХИРАЛАШ ЙЎНАЛИШИДА ҚЎЛЛАНИЛАЁТГАН ИСТИҚБОЛЛИ ТАЖРИБАЛАР
Authors: Рашидов Диловар
Published: April 2024

Мақолада ногиронлиги бўлган шахслар учун иш ўринларини захирага қўйиш бўйича Россия Федерацияси субъектларида қўлланилаётган тажрибалар атрофлича таҳлил қилинган. Бунда айниқса, ногиронлар учун ажратилаётган квота иш ўринлари миқдори, иш берувчилар учун имконияти чекланган шахсларни ишга қабул қилганликлари учун берилаётган имтиёзлар, махсус иш ўринларининг ташкил қилиниши масалалари атрофлича ўрганилган. Шунингдек, иш берувчилар томонидан квота бўйича қонунчилик талабларининг бажарилиши юзасидан назоратнинг олиб борилиши, бу йўналишдаги маълумотларнинг шаффофлиги ва ошкоралиги масалалари таҳлил қилинган.
МАҲАЛЛИЙ ВА ХОРИЖИЙ АМАЛИЁТ: ИПОТЕКА СУҒУРТАСИ МИСОЛИДА
Authors: Холматов Сухроб
Published: April 2024

Сўнгги йилларда ипотека кредитлари тобора муҳим аҳамият касб этмоқда. Шунингдек, капитал бозорининг муввақиятли ривожланиши, шу жумладан ипотека ва суғурта тизимсиз мумкин эмас. Шу нуқтаи назардан ушбу мавзу ҳамиша долзарб ва тадқиқотчиларни диққат эътиборидадир. Ушбу мақолада ипотека суғуртаси тушунчаси, унинг асосий турлари ва амал қилиш механизмлари таҳлил қилинган. Шунингдек, мақолада ушбу муносабатларнинг турли иштирокчилари учун ипотека суғуртасининг асосий афзалликлари кўрсатиб ўтилган
КОНЦЕПТУАЛЬНЫЕ ПОДХОДЫ К ТРАКТОВКЕ ПОНЯТИЯ И СУЩНОСТИ БУХГАЛТЕРСКОГО УЧЕТА
Authors: Эргашева Шахло
Published: April 2024

В статье рассматриваются концептуалные подходы к трактовке понятия и сущности бухгалтерского учета. Благодаря бухгалтерскому учету деятельность хозяйствующих субъектов определяет стабильность экономики и ее развитие. Бухгалтерский учет повышает предсказуемость результатов деятельности хозяйствующих субъектов, позволяя предугадывать и предотвращать их кризисы, а также использование финансовой отчетности позволяет снижать экономическую цикличность.
XORIJIY MAMLAKATLARNING ISHSIZ YOSHLAR RAQOBATBARDOSHLIGINI OSHIRISH BORASIDAGI TAJRIBALARI VA ULARNING YURTIMIZDA QO‘LLANILISHI
Authors: Komilova Sarvinoz
Published: April 2024

Ushbu maqolada ishsiz yoshlarni ish bilan samarali bandligi ta’minlash, ularni iqtisodiy-ijtimoiy qo‘llab-quvvatlash masalalari, yoshlarni tadbirkorlikka yo‘naltirish va bu borada xorijiy davlatlar tajribalari, olimlarning ilmiy-nazariy qarashlari tahlil qilindi. Natijada ishsiz yoshlarni bandligini ta’minlash bo‘yicha xorij tajribalari o‘rganilib, ularni mamlakatimiz iqtisodiyotiga joriy qilish istiqbollarni ko‘rsatib berildi.
XALQARO YO‘NALISHLARDA YUKLARNI TASHISHNI TASHKIL ETISHNING TARNSPORT-TERMINAL TIZIMINI SHAKLLANTIRISH VA UNING SAMARADORLIGINI OSHIRISH
Authors: Qosimov Sunnat
Published: April 2024

Ushbu maqola xalqaro yuk tashishni tashkil etish muamolarini tahlil qiladi. Ta’kidlanishicha, xalqaro yuk tashishlarda tarnsport-terminal tizimining iqtisodiy ko‘rsatkichlari samaradorligi quyidagi ko‘rsatkichlarga bog‘liq: harakatlanuvchi tarkibni tashkillashtirish va rejalashtirishning zamonaviy usullaridan foydalanish darajasi, shuningdek avtotransport korxonasi ko‘rsatkichlarining o‘sish sur’ati, transport ekpedision va bojxona ombor xizmatlari bozorining kamchiligi, bu borada barcha jahon mamlakatlarida terminal biznesining yirik logistik kompaniyalar va transport taqsimlov markazlariga integratsiyalashuvi jarayoni.
CD71: Role in permafrost immunity
Authors:   Dental Group of Sherman Oaks, Sherman Oaks, CA 91403, USA, Chiappelli Francesco ,   UCLA Center for the Health Sciences, Los Angeles, CA 90095, USA
Published: April 2024

Iron, an essential constituent of cell metabolism, is transported intra-cellularly bound to the ubiquitous 76 kDa blood glycoprotein transferrin via the transferrin receptor, CD71. Because of its structure, CD71 facilitates the binding and penetration of a large variety of viruses into the host. Among which the hemorrhagic fever-causing New World mammarenaviruses (family of single stranded ambisense segmented RNA Arenaviridae), the single stranded positive sense RNA hepatitis C virus, the single stranded negative sense segmented influenza A virus, the single stranded negative sense RNA rabies virus, the single stranded positive sense SARS-CoV2 and possibly many others. In this process, CD71 is associated with the target of the anti-proliferative antibody-1 (CD81) viral co-receptor. In light of the plethora of novel and ancient viruses and microbes emerging from melting eternal glacier ice and permafrost, it is timely and critical to define and characterize interventions, besides the soluble form of CD71 (sCD71), that can abrogate or minimize this novice non-canonical function of CD71.
Linking elevated HbA1c with atherogenic lipid profile among high risk cardiovascular patients at Qassim, Saudi Arabia
Authors:   Department of Clinical Laboratory Sciences,College of Applied Medical Sciences,University of Hail, Saudi Arabia, Akasha Rihab , Ahmad Saheem , Abdeen Rnada , Abulgasim Sara , Barnawi Heba , Elhussein Nagwan , Hussien A Rehab , Alshammari Dina Nawaf , Elafandy Nancy , Alouffi Sultan
Published: April 2024

The relationship between glycated hemoglobin (HbA1c) and an atherogenic lipid profile which is associated with a higher risk of cardiovascular disease is of interest. A retrospective cross-sectional study was conducted on 83 participants aged between 14 and 77 years. Their venous blood was drawn to determine the HbA1c and fasting lipid profile including total cholesterol triglycerides and high-density lipoprotein cholesterol (HDL-C) low-density lipoprotein cholesterol (LDL-C) non-HDL cholesterol and the LDL/HDL ratio were also calculated. The correlations between HbA1c levels and these lipid profile parameters were analyzed. The study showed a significant correlation between HbA1c and LDL-C non-HDL-C and the LDL/HDL ratio. Although there was no significant difference in total cholesterol levels among all groups the levels of total cholesterol and HbA1c were positively correlated. HDL-C exhibited direct correlations with HbA1c there was no correlation between HbA1c and clinical characteristics except for age. Data shows that HbA1c can be used as a predictor of dyslipidemia in diabetic patients there is a significant correlation between HbA1c and an atherogenic lipid profile which highlights the importance of glycemic control in reducing the risk of cardiovascular disease.
Molecular docking analysis of α-Synuclein aggregation with Anle138b
Authors:   Toxicology and Computational Biology Group, Centre for Bioinformatics, Maharshi Dayanand University, Rohtak, Haryana, India, Grewal Annu , Sheokand Deepak , Saini Vandana , Kumar Ajit
Published: April 2024

α-Synuclein aggregation into toxic oligomeric species is central to Parkinson痴 disease pathogenesis. Anle138b is a recently identified inhibitor of α-synuclein oligomerization showing promise in preclinical studies. This study employed computational approaches to elucidate Anle138b痴 mechanism of oligomer-specific action. The inhibitory potential of Anle138b against α-synuclein oligomers was evaluated by performing molecular docking studies using AutoDock Tools, followed by their binding pocket analysis. Further, protein-protein docking studies were performed using Hex8.0 to validate the aggregation inhibitory potential of Anle138b. Molecular docking revealed increasing binding affinity of Anle138b against higher order α-synuclein oligomers (dimer to decamer). Anle138b occupied oligomeric cavity and interacted with residues Thr54, Gly73, Val74 and Thr75 across several oligomers. Protein-protein docking showed that Anle138b interferes with α-synuclein decamer formation. These results highlight the oligomer-directed inhibitory mechanism of Anle138b, without hindering the monomeric forms and provide molecular insights to advance its therapeutic development for Parkinson's and related synucleinopathies.
Clinical profile of children with influenza like illness during pre-monsoon at coastal Karaikal, Puducherry, India
Authors:   Department of Paediatrics, Vinayaka Mission's Medical College and Hospital, Vinayaka Mission's Research Foundation - Deemed to be University (VMRF-DU), Karaikal, Puducherry, India, Mahesh Dande Naga , Sreelatha B ,   Department of Paediatrics, Vinayaka Mission's Medical College and Hospital, Vinayaka Mission's Research Foundation - Deemed to be University (VMRF-DU), Karaikal, Puducherry, India, Vinoth S ,   Department of Paediatrics, Vinayaka Mission's Medical College and Hospital, Vinayaka Mission's Research Foundation - Deemed to be University (VMRF-DU), Karaikal, Puducherry, India, Nancy S ,   Department of Community Medicine, Vinayaka Mission's Medical College and Hospital, Vinayaka Mission's Research Foundation - Deemed to be University (VMRF-DU), Karaikal, Puducherry, India
Published: April 2024

Influenza infections in developing countries are under reported and WHO estimates that nearly 99% of influenza deaths worldwide occur in children under-five years of age in Asian and African countries. Consequently, this study aims to analyze the use of clinical profile and easily available laboratory parameters to aid identification of the possible viral etiology in the setting of pre-monsoon ILI. A cross-sectional study was carried out for three months among children with ILI attending fever clinic of a tertiary care hospital in Karaikal, South India. In the study population the prevalence of ILI was highest in the age group four to five years followed by school aged children. Adolescents were affected the least. Influenza B was most common virus causing ILI in this region, followed by covid-19 infection. Laboratory parameters depicted a significantly high ESR in COVID-19 infected ILI children. They also exhibited leucopenia and normal platelet counts. Clinical symptoms and laboratory parameters which are easily available and cheaper can be used in resource poor settings of healthcare to identify possible influenza and COVID-19 infected children amongst cases presenting with ILI.
Insights from the SNP analysis of TYMP gene linking MNGIE
Authors:   Laboratory of Genomics and Human Genetics, Institut Pasteur du Maroc, Casablanca, Morocco, Sifeddine Najat ,   Laboratory of Physiology and Molecular Genetics, Department of Biology, Faculty of Sciences Ain Chock, Hassan II University of Casablanca, Casablanca, Morocco, Elkhattabi Lamiae ,   Laboratory of Genomics and Human Genetics, Institut Pasteur du Maroc, Casablanca, Morocco, El Cadi Chaimaa Ait ,   Laboratory of Genomics and Human Genetics, Institut Pasteur du Maroc, Casablanca, Morocco, Krami Al Mehdi ,   Laboratory of Genomics and Human Genetics, Institut Pasteur du Maroc, Casablanca, Morocco, Mounaji Khadija ,   Laboratory of Physiology and Molecular Genetics, Department of Biology, Faculty of Sciences Ain Chock, Hassan II University of Casablanca, Casablanca, Morocco, khalfi Bouchrael ,   Laboratory of Physiology and Molecular Genetics, Department of Biology, Faculty of Sciences Ain Chock, Hassan II University of Casablanca, Casablanca, Morocco, Barakat Abdelhamid ,   Laboratory of Genomics and Human Genetics, Institut Pasteur du Maroc, Casablanca, Morocco
Published: April 2024

TYMP gene, which codes for thymidine phosphorylase (TP) is also known as platelet-derived endothelial cell growth factor (PD-ECGF). TP plays crucial roles in nucleotide metabolism and angiogenesis. Mutations in the TYMP gene can lead to Mitochondrial Neurogastrointestinal Encephalopathy (MNGIE) syndrome, a rare genetic disorder. Our main objective was to evaluate the impact of detrimental non-synonymous single nucleotide polymorphisms (nsSNPs) on TP protein structure and predict harmful variants in untranslated regions (UTR). We employed a combination of predictive algorithms to identify nsSNPs with potential deleterious effects, followed by molecular modeling analysis to understand their effects on protein structure and function. Using 13 algorithms, we identified 119 potentially deleterious nsSNPs, with 82 located in highly conserved regions. Of these, 53 nsSNPs were functional and exposed, while 79 nsSNPs reduced TP protein stability. Further analysis of 18 nsSNPs through 3D protein structure analysis revealed alterations in amino acid interactions, indicating their potential impact on protein function. This will help in the development of faster and more efficient genetic tests for detecting TYMP gene mutations.
Atypical Presentation of Pulmonary Embolism Masquerading as Abdominal Pain
Authors: Alsararatee Hasan Hazim
Published: April 2024

This case report presents a rare manifestation of pulmonary embolism (PE) with atypical abdominal pain, highlighting the diagnostic challenges encountered. A female patient in her early eighties initially presented with left upper abdominal pain, initially treated for Urinary Tract Infection (UTI), and later accurately diagnosed with PE through Computed Tomography Pulmonary Angiography (CTPA). Various mechanisms of abdominal pain in PE are discussed, including right-sided heart failure-induced hepatic congestion and diaphragmatic irritation from pulmonary lobe infarction. Despite dyspnea and chest pain being more common, abdominal pain is documented in 6.7% of cases. This case underscores the importance of considering PE in the differential diagnosis of abdominal pain, particularly in the elderly population, to prevent potentially fatal consequences.
Toimiva lapsi & perhe -menetelmät: Lapset puheeksi -perheinterventio (Family Talk Intervention)
Authors: Heikkilä Lotta , Merikukka Marko , Hinkka-Yli-Salomäki Sanna , Kurki Marjo
Published: April 2024

Menetelmä lasten pärjäävyyden vahvistamiseksi perheissä, joissa vanhemmalla on mielenterveyden häiriö (2. arvio)

Kasvun tuki tuottaa systemaattisia kirjallisuuskatsauksia lapsille, nuorille ja lapsiperheille suunnatuista psykososiaalisista menetelmistä. Lisätietoja arvioinnista.

Tämä systemaattinen katsaus on Lapset puheeksi -perheintervention 2. arviointi. Menetelmä on arvioitu ensimmäisen kerran Kasvun tuki -tietolähteessä 10.6.2017.
Vaikuttavuustutkimus: Mitä tulee huomioida analysoitaessa satunnaistetun vertailukokeen aineistoa?
Authors: Hinkka-Yli-Salomäki Sanna
Published: April 2024

Artikkeli on jatkoa Kasvun tuki -aikakauslehdessä julkaistulle Vaikuttavuustutkimus-artikkelisarjalle:– Vaikuttavuustutkimus: Satunnaistettu vertailukoe tulee suunnitella huolella (2/2021)– Vaikuttavuustutkimus: Satunnaistetun vertailukokeen laadukkaan raportoinnin edellytykset (1/2022)– Vaikuttavuustutkimus: Miten arvioida harhaa satunnaistetuissa vertailukokeissa? (2/2022)

Tutkimussuunnitelmassa tai viimeistään ennen kuin avataan satunnaistamiskoodi eli tieto siitä,millä menetelmällä kutakin tutkimushenkilöä hoidetaan, on määritettävä ennakkoon kovariaatit eliselittävät muuttujat, puuttuvan tiedon käsittelymenetelmät, herkkyysanalyysit, osajoukkoanalyysitja tilastollisen hypoteesien järjestys.

Perustason kovariaatti voidaan huomioida analyysivaiheessa sisällyttämällä se tilastolliseen malliintai käyttämällä esimerkiksi ositettua satunnaistamista.

Puuttuvan tiedon huomiotta jättäminen rikkoo hoitoaieperiaatetta, jonka mukaan analyyseihinsisällytetään kaikki satunnaistetut tutkittavat.

Monivertailuongelman välttämiseksi satunnaistetuissa vertailukokeissa kannattaa käyttää vain yhtäpäävastetta. Mikäli tämä ei ole mahdollista, on käytettävä monivertailun huomioivia menetelmiä.

Osajoukkoanalyysien tulokset ovat tärkeä esittää estimaattien ja luottamusvälien avulla, sillä pelkkäkäsittelyryhmän ja kovariaatin yhdysvaikutuksen p-arvon esittäminen ei yksin riitä.
BV2TrS Appraiser Model: Enforcing BHARAT Version2 in Tree Soft Modelling for Appraising E-Mobility Hurdles
Authors: Mohamed Mona , Smarandache Florentin , Voskoglou Michael
Published: April 2024

Electric vehicles (EVs) are being introduced to lessen greenhouse gas (GHG) emissions, air pollution, and reliance on fossil fuels. As a result of the government's aggressive promotion of EVs and rising environmental consciousness, EVs are quickly rising to the top of the low-carbon transportation market. Several viewpoints suggested that shifting to electric vehicles has been seen as a potential way to achieve sustainable mobility. Nevertheless, many studies discussed the obstacles and hurdles that obstruct the embracing of various electric-mobility (E-mobility) as EVs and electric-scooters (E-scooters) as eco-friendly means. Herein, we discussed these hurdles and determined them through surveys for prior studies. Therefore, appraising these hurdles is the objective of our study. Best Holistic Adaptable Ranking of Attributes Technique – version 2 (BHARAT -v2) as a novel Multi-Criteria Decision Making (MCDM) technique is leveraged as an appraiser technique for these hurdles. Tree Soft (TrS) methodology is utilized for modeling these hurdles. Hence, we hybridized and integrated two methodologies for constructing BHARAT v2 Tree Soft (Bv2TrS) as an appraiser model. Subsequently, we discussed the findings of the Bv2TrS appraiser model.
Implementing Foundations of Quality through Online and Hybrid Course Design: A Study-Away Course Case Study
Authors: Williams Florence
Published: April 2024

The far reaching social, political, and economic COVID-19 pandemic profoundly impacted students, leading to significant changes in the online learning landscape. Disengagement in e-classrooms due to external distractions prompted educators, even those experienced in diverse course formats, to seek innovative ways to foster engagement. In this case-based qualitative research on course design quality, a student-facing higher education instructor and a faculty-assisting instructional designer employed qualitative methods to explore quality components and transform a study-away course. Key steps included effective instruction, intentional design, inclusive environments, learner-centred approaches, engaging activities, and community focus. The findings revealed that the recursive ADDIE (Analysis, Design, Development, Implementation, and Evaluation) process facilitated reflection and meaningful change within these foundations of quality. We propose a learner-centric model where students are architects of their development, and faculty function as facilitators. These adaptable methods span disciplines and formats, informing future education research and practice. Keywords: study-away course, course improvement, higher education, instructional design, quality
69| J o u r n a l o f A d u l t E d u c a t i o n i n T a n z a n i aChallenges Facing Teenage Mothers Re-Admitted to Non-Formal Education System in Tanzania: Empirical Evidence from Learners at Wamo Open School, Morogoro Municipality
Authors: Mmasy Zawadi
Published: April 2024

In Tanzania, as in many other low and middle-income countries, teenage pregnancy rates remain high, with cultural, socioeconomic and structural factors contributing to early and unintended pregnancies among adolescents. This study focused on the challenges facing teenage mothers re-admitted to non-formal education in Tanzania. The study was qualitative and employed a purposive sampling technique to select 20 participants from Wamo Open School. Data was analysedqualitatively. The findings revealed that teenage mothers re-admitted to non-formal education in Tanzania faced a myriad of challenges namely, stigma and discrimination from peers and community members, lack of financial resources, childcare responsibilities, dropout risk, and limited future opportunities. Finally, the study recommends that Wamo Open School, Morogoro Municipality should develop and implement comprehensive support services tailored to the needs of teenage mothers re-admitted to non-formal education programs. Keywords: Teenage mothers, non-formal education, challenges, re-admission, Tanzania
Valtion historiamonopoli ja historiatietoisuus Venäjällä
Authors: Parppei Kati
Published: April 2024

Essee käsittelee nykyvenäläistä menneisyyspolitiikkaa historiatietoisuus-käsitteen valossa. Muutamien esimerkkien avulla esseessä tarkastellaan sitä, miten Venäjän valtio pyrkii kontrolloimaan menneisyyden ymmärtämistä ja käsitteellistämistä sekä ohjailemaan muistamista.
Euroopan parlamentti, Ylikansallinen kulttuurinen muisti ja holokausti
Authors: Holmila Antero
Published: April 2024

Tässä artikkelissa tutkin, miten ja ennen kaikkea miksi holokaustista tuli ylikansallisen ja yleiseurooppalaisen muistipolitiikan keskeinen opinkappale. Holokaustin kulttuurisen muistin kehittymisprosessia tulkitaan Jan Assmannin kulttuurisen muistin viitekehyksen avulla. Tavoitteenani on soveltaa Assmannin teoreettista kehystä käytännön muistipolitiikan tutkimiseen. Keskeisen lähdeaineiston muodostavat Euroopan parlamentin (EP) asiakirjat. Tekstin ensimmäinen osio avaa Euroopan yhdentymisen konteksteja, erityisesti sitä, miten ”identiteettinen yhdentyminen” nousi integraatiopolitiikassa yhtä merkittävämpään osaan 1990-luvulta alkaen ja miksi holokausti sai niin korostuneen roolin identiteettien muokkauksessa. Työn toinen osio avaa Assmannin kulttuurisen muistin näkökulmasta, miten ja miksi EP instrumentalisoi holokaustin muistipolitiikkansa ytimeen.
Effect of Corporate Governance Practices on the Performance of an Established Medium-Sized Enterprise in the Mining Industry in South Africa
Authors: Mokalapa Phenyane Mighty , Oyedokun Godwin Emmanuel , Fowokan Titilayo Eni-Itan
Published: April 2024

It is evident that SMEs have formed a significant part of the broader South African mining industry, faced their fair share of constraints and challenges, and often experienced a high failure rate. In light of this, the research objective of this study is to identify the CG practices followed by an established medium-sized enterprise in the mining industry. The study explored ethical culture, good performance, effective control, and legitimacy as CG outcomes in this particular SME, aiming to determine whether these practices have effectively addressed the challenges faced by SMEs. The study employed a qualitative research approach with two stages. First, a review of previous research regarding SME challenges. Second, a case study research design with a single medium-sized enterprise mine in the North-West province will be used as the unit of analysis. Data were collected using MS Teams, telephonic, and semi-structured interviews. The transcribed interviews were analyzed using Microsoft Excel. The SME demonstrated a strong ethical culture, achieved good performance through regular performance reporting and evaluation of the company’s core purpose, aligned to the effective control theme since the SME has a unique governing body and addresses the challenges of their size by implementing a governance structure and delegating authority and holds regular meetings with internal and external stakeholders to maintain a good relationship with stakeholders in order to fulfill the legitimacy theme. The study, therefore, concluded that CG outcomes are well understood and practiced by SMEs in the mining industry, affirming the effectiveness of these practices in addressing the challenges faced by SMEs.
DETECTION OF FRAUDULENT OR DECEPTIVE PHONE CALLS USING ARTIFICIAL INTELLIGENCE
Authors: RATNAKUMARI Mrs J. , THAHENATH SHAIK NAILO ASMIN , LAKSHMI TOLUSURI SRI , KUMAR PERAVALI NAGA DILEEP , VEERAIAH KADIYAM
Published: April 2024

With an increase advancement of technology, fraud phone calls, including spam’s and malicious calls have become a major concern in telecommunication industry and causes millions of global financial losses every year. Fraudulent phone calls or scams and spams via telephone or mobile phone have become a common threat to individuals and organizations. Artificial Intelligence (AI) and Machine Learning (ML) has emerged as powerful tools in detecting and analyzing fraud or malicious calls. This project presents an overview of AI-based fraud or spam detection and analysis techniques, along with its challenges and potential solutions. The novel fraud call detection approach is proposed that achieved high accuracy and precision. The Proposed approach was evaluated using a dataset of real-world fraudulent calls. And results demonstrate that the approach achieved high accuracy in detecting malicious calls and identifying potential indicators of frauds or spam’s. The analysis of fraud calls also provided insights into the tactics and methods employed by fraudsters, which can be used to develop countermeasures.
A ROBUST DETECTION FRAUDULENT TRANSACTIONS IN BANKING USING MACHINE LEARNING
Authors: KUMAR Mr N. KISHORE , UMASWATHIKA ALAVALA , YASWANTHKUMAR KUMMARA , MADHUMITHA BITRA
Published: April 2024

Vulnerability in banking systems has exposed us to fraudulent acts, which cause severe damage to both customers and the bank in terms of loss of money and reputation. Financial fraud in banks is estimated to result in a significant amount of financial loss annually. Early detection of this helps to mitigate the fraud, by developing a counter strategy and recovering from such losses. A machine learning-based approach is proposed in this paper to contribute to fraud detection successfully. The artificial intelligence (AI) based model will speed up the check verification to counteract the counterfeits and lower the damage. In this paper, we analyzed numerous intelligent algorithms trained on a public dataset to find the correlation of certain factors with fraudulence. The dataset utilized for this research is resampled to minimize the high class of imbalance in it and analyzed the data using the proposed algorithm for better accuracy.
A RARE COMPLICATION: ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS) INDUCED BY SEVERE PNEUMOCYSTIS CARINII PNEUMONIA (PCP)
Authors: Prasetya Wijaya Gede Adi , Yanti Andi
Published: April 2024

Introduction: Pneumocystis pneumonia (PCP) represents a prevalent opportunistic infection among individuals with HIV, posing a significant risk of mortality. The occurrence of acute respiratory distress syndrome (ARDS) as a consequence of PCP further accentuates the gravity and intricacy of this pulmonary infection.
Objective: This case report aims to discuss the management of the rare complication of ARDS induced by severe PCP in a 36-year-old man with HIV.
Case Presentation: A 36-year-old male teacher, presented with worsening dyspnea, intermittent fever, and a productive cough persisting for two weeks, along with weight loss and fatigue. Initial diagnostic impressions included pulmonary tuberculosis with pneumonia. Treatment involved oxygen therapy, fluid administration, and medication. Laboratory tests showed leukocytosis, elevated blood glucose, and abnormal liver function. Subsequent investigations confirmed HIV infection. Chest X-ray revealed severe bilateral pneumonia and possible ARDS, leading to transfer to the Intensive Care Coronary Unit for further management.
Discussion: The diagnosis of severe Pneumocystis jirovecii pneumonia (PCP) underscores the importance of recognizing PCP as a significant clinical concern, especially in HIV patients. Diagnostic challenges, such as late HIV diagnosis, highlight the need for timely screening and intervention. Management involved a multidisciplinary approach, including pulmonologists and cardiologists. Despite treatment adjustments, some patients experience clinical deterioration, necessitating careful management strategies like antiretroviral (ARV) therapy and respiratory support. This case underscores the complexity of managing PCP-related ARDS and the crucial role of timely intervention and comprehensive care.
Conclusion: Severe PCP led to ARDS in an HIV-infected patient due to inflammation and lung damage, exacerbated by the immunocompromised state. Timely diagnosis and treatment are crucial to prevent complications and improve outcomes in such cases.
ERA DIGITAL: TANTANGAN DAN PELUANG DALAM DUNIA KERJA
Authors: Agustina Rina , Nur'aini Silva , Nazla Luluwatun , Hanapiah Siti , Marlina Lina
Published: April 2024

Perusahaan yang mampu memanfaatkan teknologi dengan efektif dan efisien dapat mengembangkan model bisnis baru, menciptakan lapangan kerja baru, dan memperluas segmentasi pasar. Para pekerja dapat memanfaatkan teknologi untuk meningkatkan produktivitas, meningkatkan kreativitas, dan mengakses kesempatan kerja secara global. Namun, dengan adanya hal tersebut dihadapkan dengan tantangan yang cukup signifikan karena omatisasi dan kecerdasan buatan dapat menggantikan pekerjaan manusia dalam beberapa sektor, pekerjaan inilah yang dilakukan oleh mesin cenderung terancam penggantian, yang dapat menyebabkan peningkatan angka pengangguran. Penelitian ini bertujuan untuk memahami tantangan yang dihadapi oleh individu terkait pengganguran di era digital, serta menganalisis peluang dalam dunia kerja yang dapat muncul dalam menghadapi tantangan untuk mengurangi tingkat pengangguran. Jenis penelitian yang digunakan ialah pendekatan kualitatif dengan teknik library research atau kajian kepustakaan yakni dengan mengumpulkan data dari buku, majalah, atau dokumen terkait yang dapat mendukung penelitian. Hasil penelitian ini menjelaskan bahwasannya pentingnya masyarakat untuk terus belajar dan beradaptasi dengan cepat serta kemampuan untuk menguasai teknologi dan mengembangkan keterampilan yang relevan akan menjadi kunci sukses dalam menghadapi perubahan yang terjadi di dunia kerja yang kini semakin digital
ANALISIS STRATEGI PEMASARAN KAIN SONGKET DALAM MENINGKATKAN PENDAPATAN UMKM DI KOTA PALEMBANG
Authors: Nurijal  , Rista April Diyanti  , Fitriyeni  , Monica Adela , Maya Panorama
Published: April 2024

Abstrak Pemasaran merupakan faktor kunci yang perlu diperhatikan untuk memenuhi atau menarik konsumen yang diharapkan. Berbagai jenis UMKM yang ada dan berbagai jenis produk yang ditawarkan semuanya hampir sama, karena produk UMKM mudah dibuat dengan bahan yang murah, perlu inovasi yang lebih kreatif agar menarik. Tujuan dari penelitian ini ialah untuk mengetahui bagaimana strategi pemasaran dalam meningkatkan pendapat. Dengan bantuan analisis SWOT, untuk mengetahui seberapa berorientasi target strategi pemasaran. Hal ini meliputi faktor internal yaitu kekuatan dan kelemahan, dan faktor eksternal yaitu peluang dan ancaman kepemilikan UMKM. Teknik pengumpulan data melalui dokumentasi, wawancara dan observasi. Teknik analisis data menggunakan penelitian dokumen dan deskriptif analitik. Hasil dari penelitian ini menyimpulkan bahwa Sesuai dengan judul dan tujuan dari penelitian ini serta telah diuraikan mengenai lokasi penelitian dan analisa SWOT yang sudah diuraikan secara mendalam. Pada kegiatan UMKM memilki faktor internal atau sumber daya manusia dalam hal ini UMKM Pondok Kain Songket Yuk Nita memiliki berbagai jenis kain dan masih terus berinovasi agar tetap diterima di pasaran.
Kata Kunci   Strategi Pemasaran, UMKM, Pendapatan.Abstrak Pemasaran merupakan faktor kunci yang perlu diperhatikan untuk memenuhi atau menarik konsumen yang diharapkan. Berbagai jenis UMKM yang ada dan berbagai jenis produk yang ditawarkan semuanya hampir sama, karena produk UMKM mudah dibuat dengan bahan yang murah, perlu inovasi yang lebih kreatif agar menarik. Tujuan dari penelitian ini ialah untuk mengetahui bagaimana strategi pemasaran dalam meningkatkan pendapat. Dengan bantuan analisis SWOT, untuk mengetahui seberapa berorientasi target strategi pemasaran. Hal ini meliputi faktor internal yaitu kekuatan dan kelemahan, dan faktor eksternal yaitu peluang dan ancaman kepemilikan UMKM. Teknik pengumpulan data melalui dokumentasi, wawancara dan observasi. Teknik analisis data menggunakan penelitian dokumen dan deskriptif analitik. Hasil dari penelitian ini menyimpulkan bahwa Sesuai dengan judul dan tujuan dari penelitian ini serta telah diuraikan mengenai lokasi penelitian dan analisa SWOT yang sudah diuraikan secara mendalam. Pada kegiatan UMKM memilki faktor internal atau sumber daya manusia dalam hal ini UMKM Pondok Kain Songket Yuk Nita memiliki berbagai jenis kain dan masih terus berinovasi agar tetap diterima di pasaran.Kata Kunci Strategi Pemasaran, UMKM, Pendapatan.
Código de Buenas Prácticas de la UE en Materia de Desinformación
Authors: Espaliú Berdud Carlos
Published: April 2024

Entre los instrumentos que la UE ha impulsado en la lucha contra la desinformación destaca el Código de buenas prácticas sobre desinformación, elaborado por las principales plataformas digitales en 2018 y de carácter básicamente autorregulador. Tras su aplicación, se detectaron algunas deficiencias, que se abordaron mediante la redacción de una nueva versión reforzada del código en 2022. Aunque responde a las mismas características que el Código de 2018, su eficacia real se ve consolidada al formar parte de un marco jurídico más amplio, en conjunción con la DSA entre otros instrumentos. En efecto, creemos que sólo un esfuerzo colectivo, tanto de los actores privados en este ámbito, como de las autoridades nacionales e internacionales, y siguiendo un enfoque multidisciplinar, garantiza la capacidad de combatir al monstruo de la desinformación que atemoriza a las sociedades contemporáneas. Todo ello sin olvidar el respeto a las libertades esenciales de información y expresión.