bluuebunny/crossref_metadata_2025 huggingface dataset:
Freeze-Thaw Behaviour of Post-Installed Bonded Anchors under Changing Climate Conditions
Authors: Stierschneider Elisabeth , Zeman Oliver , Bergmeister Konrad
Published: April 2022

The freeze-thaw behaviour of bonded fasteners in concrete is assessed according to the European Assessment Document 330499-01-0601 with freeze-thaw condition tests, which include 50 temperature cycles with a duration of 24 h between −20 °C and +20 °C on constantly loaded anchors. It is assumed that one cycle is equivalent to the temperature difference, which a bonded fastener undergoes in one year. Based on an analysis of a 28-year time series of air temperature data for Austria respecting the Alpine region, a modified test protocol with a temperature amplitude of 65 °C between −20 °C and +45 °C is compiled without a predefinition of the number of cycles, in order to simulate temperature differences that occur under real climatic conditions. The experimental test results obtained for both test procedures demonstrate that the stabilization of the displacements for the modified test series occurred after 185 temperature cycles, compared to the 50 cycles for the standard method. This means that an increase in the temperature amplitude of 25 °C in the higher temperature range leads to an approximately 3.5 times higher number of required temperature cycles until displacement stabilization is reached. It is concluded that the definition of the used temperature range for freeze-thaw testing in conjunction with climatic data should be critically considered, in order to possibly adapt pure freeze-thaw tests towards experiments that take into account real annual temperature differences.
Fabrication, Design and Characterization of 1D Nano-Fibrous SiO2 Surface by a Facile and Scalable Method
Authors: Khouchaf Lahcen , Oufakir Abdelhamid
Published: April 2022

In this paper, new 1D nano-fibrous SiO2 with functionalized surfaces is prepared. First, the effect of dispersion on the morphology and the surface properties of the silica SiO2 compounds are investigated. Second, energy dispersive spectrometer (EDS) and variable pressure scanning electron microscope (VP-SEM) show typically pure and fibrous texture on the surface of SiO2. Third, the presence of the bridging oxygen stretching vibration Si-O-Si, as well as the increase in the intensity ratio between Si-OH band and Si-O-Si are revealed by (FTIR) spectroscopy. Furthermore, X-ray diffraction (XRD) validates the conservation of the SiO lattice after chemical treatment through the KOH for both dispersed and non-dispersed samples. In addition, the shift of the XRD main peak (101) is in good agreement with the FTIR results showing the shift of Si-O-Si peak and the increase in the intensity ratio of Si-OH/Si-O-Si. The dispersed SiO2 sample exhibits a promising functionalized surface with satisfactory results in terms of silica nanofibers crystallinity and chemical composition. As a result, gigh resolution transmission electron microscopy (HR-TEM) data corroborate the claim of the presence of SiO2 nanofibers on the surface from 20 nm to 250 nm. New nano-fibrous SiO2 surfaces will be used to improve interfacial bonding strength between SiO2 compounds and polymer (or organic materials).
Development of Cistanche deserticola Fermented Juice and Its Repair Effect on Ethanol-Induced WRL68 Cell Damage
Authors: Yang Zhenzhen , Wang Liang
Published: April 2022

Cistanche deserticola is a valuable Chinese herb, but traditional dry processing causes the loss of active substances. This study developed Cistanche deserticola fermented juice (CFJ) using lactic acid bacteria and optimized the fermentation process to achieve the maximum active substance content and taste. More interestingly, superoxide dismutase (SOD) activity was increased during fermentation, and CFJ exerted a reparative effect on ethanol-induced cell damage. SOD activity reached 603.26 U/mL when the ratios in the total inoculum volume of Lactobacillus reuteri, Lactococcus pentosus, Streptococcus thermophilus, Bifidobacterium animalis, Lactobacillus casei, and Lactobacillus acidophilus were 31.74%, 15.71%, 17.45%, 11.65%, 9.56%, and 13.89%, respectively. Further, the optimal fermentation conditions for CFJ were determined using a response surface methodology. More importantly, CFJ promoted the proliferation of WRL68 cells, and CFJ exerted an obvious reparative effect on ethanol-treated cells, in which the cell survival rate increased to 120.35 ± 0.77% (p < 0.05). The underlying mechanism might have been that CFJ reduced the MDA content in damaged cells from 1.36 nmol/mg prot to 0.88 nmol/mg prot and increased GSH-Px and SOD activities by 48% and 72%, respectively. This study provides a theoretical basis and reference data for the fermentation of C. deserticola and its hepatoprotective activity.
The Variation of Soil Phosphorus Fractions and Microbial Community Composition under Consecutive Cucumber Cropping in a Greenhouse
Authors: Bian Ting , Zheng Shiwei , Li Xiao , Wang Shuang , Zhang Xiaolan , Wang Zhen , Li Xiaoxia , Fu Hongdan , Sun Zhouping
Published: April 2022

The distribution of phosphorus (P) fractions in soil plays a decisive role in soil P bioavailability; however, the characteristics of soil P fractions under consecutive cropping in a solar greenhouse remain unclear. To evaluate the effects of the long-term successive vegetable cropping on soil P fractions and the microbial community composition in greenhouse soil, a continuous long-term cropping experiment was conducted using cucumber (Cucumis sativus L.) in a solar greenhouse starting from 2006 to 2018. Soil P fractions and the microbial community composition were determined using the Hedley continuous extraction method and the phospholipid fatty acid (PLFA) method, respectively, in the 1st, 9th, 13th, and 21st rounds of cultivation. The soil total phosphorus (TP) content increased from 0.90 g·kg−1 in the 1st round to 3.07 g·kg−1 in the 21st round of cucumber cultivation. With an increase in continuous cropping rounds, soil available phosphorus (AP) increased and the phosphorus activation coefficient (PAC) decreased, with no significant difference between the 13th and 21st rounds. After 21 rounds of continuous cropping, the soil organic matter (SOM) content was 16.34 g·kg−1, 1.42 times that of the 1st round. The abundance of soil bacteria, actinomycetes, Gram-negative bacteria (G−), Gram-positive bacteria (G+), and total PLFAs initially increased with continuous cropping rounds, but then decreased significantly, and the ratios of fungi:bacteria (F/B) and G+/G− bacteria also increased significantly with continuous cropping rounds. The contents of soil labile P, moderately labile P, and non-labile P increased significantly over 21 continuous cropping rounds. Together, these results demonstrate that long-term continuous cropping can directly lead to the accumulation of P fractions, but it can also affect the abundance of actinomycetes through SOM enrichment, which indirectly leads to the accumulation of non-labile P. This study provides a theoretical basis for future soil P fertilizer management and vegetable production sustainability.
Alzheimer’s Disease and Tau Self-Assembly: In the Search of the Missing Link
Authors: González Andrea , Singh Sandeep Kumar , Churruca Macarena , Maccioni Ricardo B.
Published: April 2022

Alzheimer’s disease (AD) is a multifactorial neurodegenerative disease characterized by progressive cognitive impairment, apathy, and neuropsychiatric disorders. Two main pathological hallmarks have been described: neurofibrillary tangles, consisting of tau oligomers (hyperphosphorylated tau) and Aβ plaques. The influence of protein kinases and phosphatases on the hyperphosphorylation of tau is already known. Hyperphosphorylated tau undergoes conformational changes that promote its self-assembly. However, the process involving these mechanisms is yet to be elucidated. In vitro recombinant tau can be aggregated by the action of polyanions, such as heparin, arachidonic acid, and more recently, the action of polyphosphates. However, how that process occurs in vivo is yet to be understood. In this review, searching the most accurate and updated literature on the matter, we focus on the precise molecular events linking tau modifications, its misfolding and the initiation of its pathological self-assembly. Among these, we can identify challenges regarding tau phosphorylation, the link between tau heteroarylations and the onset of its self-assembly, as well as the possible metabolic pathways involving natural polyphosphates, that may play a role in tau self-assembly.
Strengthening of Mg-6Al-1Zn Alloy via Simultaneous Loading and Aging
Authors: He Jiejun , Wu Lushu
Published: April 2022

An obvious strengthening phenomenon has been observed in the Mg-6Al-1Zn (AZ61) alloy after simultaneous loading and aging at 170 °C. Being different to aging after pre-strain, the simultaneous loading and aging can obviously increase the yield stress of the alloy. Microstructural analysis shows that a larger quantity of the Al12Mg17 can be obtained by simultaneous loading and aging in a relatively short aging time, compared with aging after pre-strain. It is speculated that the loading during aging is more beneficial for nucleation of the precipitates. In the same aging time, it is found that the sample subjected to simultaneous loading and aging shows a higher yield stress than the sample aged after pre-strain. To extend aging time, a large quantity of Al12Mg17 can be obtained in the pre-strained sample. However, it is demonstrated that the yield stress of the sample subjected to aging after pre-strain is lower than that of the sample subjected to simultaneous loading and aging, despite these two samples containing the same quantity of precipitates. It is speculated that the occurrence of the precipitates plays a role in preventing dislocation gliding and twin expanding, thus leading to a strengthening effect. Additionally, atoms segregated in twin boundaries may partly strengthen the material. It is found that a large quantity of precipitates can be obtained in a relatively short aging time by using the simultaneous loading and aging, reducing the softening effect caused by aging. The observed phenomenon may provide a new strategy for strengthening magnesium alloys.
Three Preceding Crops Increased the Yield of and Inhibited Clubroot Disease in Continuously Monocropped Chinese Cabbage by Regulating the Soil Properties and Rhizosphere Microbial Community
Authors: Zhang Yiping , Li Wei , Lu Peng , Xu Tianyu , Pan Kai
Published: April 2022

Crop rotation can improve soil properties and is one of the important measures to prevent soil-borne diseases. This study aimed to evaluate the effects of different preceding crops on clubroot disease in Chinese cabbage and soil microorganisms, to provide a theoretical basis for the ecological control of clubroot scientifically. In this experiment, soybeans, potato onions, and wheat were used as the preceding crops and compared with the local preceding crop garlic. The growth of the Chinese cabbage, disease occurrence, soil chemical properties and changes in microbial community structure were determined by using quantitative real-time polymerase chain reaction (PCR), soil microbial high-throughput sequencing and other methods. The results showed that the rotation of potato onion and wheat with Chinese cabbage could reduce the clubroot disease index of Chinese cabbage remarkably. Through Illumina Miseq sequencing, when three previous crops were harvested, the abundance and diversity of the bacteria increased obviously, while the fungi decreased. The relative abundance of the phylum Proteobacteria and Firmicutes was strikingly reduced, while that of Chloroflexi was significantly increased. These results show that three previous crops changed the structure of soil microorganisms, reduced the clubroot disease of Chinese cabbage, promoted growth, and suppressed disease. The ranked effect on promoting growth and inhibiting diseases was potato onion > wheat > soybean.
Design and Implementation of an ML and IoT Based Adaptive Traffic-Management System for Smart Cities
Authors: Lilhore Umesh Kumar , Imoize Agbotiname Lucky , Li Chun-Ta , Simaiya Sarita , Pani Subhendu Kumar , Goyal Nitin , Kumar Arun , Lee Cheng-Chi
Published: April 2022

The rapid growth in the number of vehicles has led to traffic congestion, pollution, and delays in logistic transportation in metropolitan areas. IoT has been an emerging innovation, moving the universe towards automated processes and intelligent management systems. This is a critical contribution to automation and smart civilizations. Effective and reliable congestion management and traffic control help save many precious resources. An IoT-based ITM system set of sensors is embedded in automatic vehicles and intelligent devices to recognize, obtain, and transmit data. Machine learning (ML) is another technique to improve the transport system. The existing transport-management solutions encounter several challenges resulting in traffic congestion, delay, and a high fatality rate. This research work presents the design and implementation of an Adaptive Traffic-management system (ATM) based on ML and IoT. The design of the proposed system is based on three essential entities: vehicle, infrastructure, and events. The design utilizes various scenarios to cover all the possible issues of the transport system. The proposed ATM system also utilizes the machine-learning-based DBSCAN clustering method to detect any accidental anomaly. The proposed ATM model constantly updates traffic signal schedules depending on traffic volume and estimated movements from nearby crossings. It significantly lowers traveling time by gradually moving automobiles across green signals and decreases traffic congestion by generating a better transition. The experiment outcomes reveal that the proposed ATM system significantly outperformed the conventional traffic-management strategy and will be a frontrunner for transportation planning in smart-city-based transport systems. The proposed ATM solution minimizes vehicle waiting times and congestion, reduces road accidents, and improves the overall journey experience.
Cooperatively Routing a Truck and Multiple Drones for Target Surveillance
Authors: Tian Shuangxi , Wen Xupeng , Wei Bin , Wu Guohua
Published: April 2022

With the development of drone technology, drones have been deployed in civilian and military fields for target surveillance. As the endurance of drones is limited, large-scale target surveillance missions encounter some challenges. Based on this motivation, we proposed a new target surveillance mode via the cooperation of a truck and multiple drones, which enlarges the range of surveillance. This new mode aims to rationally plan the routes of trucks and drones and minimize the total cost. In this mode, the truck, which carries multiple drones, departs from its base, launches small drones along the way, surveils multiple targets, recycles all drones and returns to the base. When a drone is launched from the truck, it surveils multiple targets and flies back to the truck for recycling, and the energy consumption model of the drone is taken into account. To assist the new problem-solving, we developed a new heuristic method, namely, adaptive simulated annealing with large-scale neighborhoods, to optimize truck and drone routes, where a scoring strategy is designed to dynamically adjust the selection weight of destroy operators and repair operators. Additionally, extensive experiments are conducted on several synthetic cases and one real case. The experimental results show that the proposed algorithm can effectively solve the large-scale target surveillance problem. Furthermore, the proposed cooperation of truck and drone mode brings new ideas and solutions to targets surveillance problems.
A High-Performance Thin-Layer Chromatographic Method for the Simultaneous Determination of Curcumin I, Curcumin II and Curcumin III in Curcuma longa and Herbal Formulation
Authors: Abdel-Kader Maged S. , Salkini Ayman A. , Alam Prawez , Alshahrani Khaled A. , Foudah Ahmed I. , Alqarni Mohammed H.
Published: April 2022

Curcuma longa (turmeric) has traditionally been used in Ayurvedic, Unani and herbal drugs to cure numerous ailments. Due to the high demand, the quantitative standardization of herbal products is challenging to maintain their quality. We aim to develop a rapid, sensitive and validated high-performance thin-layer chromatography (HPTLC) method for the simultaneous determination and quantification of curcumin I, curcumin II and curcumin III in C. longa and herbal formulation. The three standards were separated using centrifugal preparative thin-layer chromatography (CPTLC) silica gel and identified by different spectroscopic methods. The developed HPTLC method was validated by following ICH guidelines (linearity; limit of detection, LOD; limit of quantitation; accuracy; precision; and robustness). The calibration curves of both the compounds were linear (50–500 ng/spot), with a correlation coefficient (r2) of >999. The developed HPTLC method was effectively applied to the concurrent detection and quantification of curcumins I–III in fresh, dry rhizomes and the herbal formulation of C. longa extracts was obtained by hot and cold extraction methods.
Proteomic Studies of the Mechanism of Cytotoxicity, Induced by Palytoxin on HaCaT Cells
Authors: Cheng Dingyuan , Deng Bowen , Tong Qiling , Gao Siyi , Xiao Boyi , Zhu Mengxuan , Ren Ziyu , Wang Lianghua , Sun Mingjuan
Published: April 2022

Palytoxin (PLTX) is a polyether marine toxin isolated from sea anemones. It is one of the most toxic nonprotein substances, causing many people to be poisoned every year and to die in severe cases. Despite its known impact on Na+,K+-ATPase, much still remains unclear about PLTX’s mechanism of action. Here, we tested different concentrations of PLTX on HaCaT cells and studied its distributions in cells, its impact on gene expression, and the associated pathways via proteomics combined with bioinformatics tools. We found that PLTX could cause ferroptosis in HaCaT cells, a new type of programmed cell death, by up-regulating the expression of VDAC3, ACSL4 and NCOA4, which lead to the occurrence of ferroptosis. PLTX also acts on the MAPK pathway, which is related to cell apoptosis, proliferation, division and differentiation. Different from its effect on ferroptosis, PLTX down-regulates the expression of ERK, and, as a result, the expressions of MAPK1, MAP2K1 and MAP2K2 are also lower, affecting cell proliferation. The genes from these two mechanisms showed interactions, but we did not find overlap genes between the two. Both ferroptosis and MAPK pathways can be used as anticancer targets, so PLTX may become an anticancer drug with appropriate modification.
The Prostate Cancer Immune Microenvironment, Biomarkers and Therapeutic Intervention
Authors: Zhang Yangyi , Campbell Bethany K. , Stylli Stanley S. , Corcoran Niall M. , Hovens Christopher M.
Published: April 2022

Advanced prostate cancers have a poor survival rate and a lack of effective treatment options. In order to broaden the available treatments, immunotherapies have been investigated. These include cancer vaccines, immune checkpoint inhibitors, chimeric antigen receptor T cells and bispecific antibodies. In addition, combinations of different immunotherapies and with standard therapy have been explored. Despite the success of the Sipuleucel-T vaccine in the metastatic, castrate-resistant prostate cancer setting, other immunotherapies have not shown the same efficacy in this population at large. Some individual patients, however, have shown remarkable responsiveness to these therapies. Therefore, work is underway to identify which populations will respond positively to therapy via the identification of predictive biomarkers. These include biomarkers of the immunologically active tumour microenvironment and biomarkers indicative of high neoantigen expression in the tumour. This review examines the constitution of the prostate tumour immune microenvironment, explores the effectiveness of immunotherapies, and finally investigates how therapy selection can be optimised by the use of biomarkers.
Food security issues: root causes and directions for the future
Authors: Manate Maimiti , Cherrington Marianne
Published: April 2022

The second United Nations Sustainable Development Goal is Zero Hunger. The issue stems from multiple root-causes that must be recognised and managed, to reduce the consequences of acute hunger and undernourishment. Two closely related topics are food security and food poverty. While the characterisation of these two problems is different, their causes are closely related. Aotearoa, New Zealand is confronting these problems as well, even though the country is exporting a significant amount of food from agricultural production. This paper is a realist review of food security issues in Aotearoa, New Zealand; the method aligns with selected secondary reviews devised for complex policy interventions. The focus is on several interdependent topics such as the living wage, eating habits, and the food system. While income is the most obvious aspect of a living wage, it is important to be aware of many encompassing factors such as eating habits. The food system is directly related to these issues and needs to evolve simultaneously and considerably. Fortunately, Aotearoa, New Zealand is rich in resources and culture; Māori culture influences our food industry. This paper will particularly discuss hāngī (traditional, earth-cooked food) and its connection to agriculture in Aotearoa, New Zealand. The paper outlines an alternative food system as one possible response that can be developed and adopted in the future.
Magnesium Sulfate for Prevention of Post-ERCP-Pancreatitis: A Randomized Controlled Trial
Authors: Aletaha Najmeh , Hamid Hoda , Alipour Abbas , Ketabi Moghadam Pardis
Published: April 2022

Background: Acute pancreatitis is one of the most common complications of endoscopic retrograde cholangiopancreatography (ERCP). Studies suggest that intrapancreatic calcium has an important role in activating pancreatic enzymes; in addition, elevated intraductal pressure is required for development of pancreatitis. Magnesium sulfate (MS), as a calcium antagonist and a muscle relaxant of the Oddi sphincter, is suggested to reduce the incidence and severity of post-ERCP-pancreatitis (PEP) in this article. Methods: We included 270 patients who referred for ERCP between March 2017 and March 2018. They were enrolled into MS (2 g) and placebo (normal saline) groups, administered 1 hour before and 6 hours after the procedure. The ERCPs were done by fellows of gastroenterology under supervision of expert physicians. The incidence and severity of PEP were followed. Results: PEP was seen in 12 (8.9%) patients in the MS group and 17 (12.6%) in the placebo group (P value=0.33). The incidence of PEP in high risk patients group (P value=0.017). Conclusion: Although the usage of MS was not able to prevent PEP in all patients enrolled in this study, but it could significantly reduce the incidence of PEP in high risk patients of intervention group in comparison with placebo group. The median length of hospital stay was also significantly lower in new drug group in contrast to placebo.
CpG Island Methylation of the Rap1Gap Gene in Medullary Thyroid Cancer
Authors: Faam Bita , Ghadiri Ata. A , Ghaffari Mohammad Ali , Totonchi Mehdi , Amouzegar Atieh , Azizi Fereidoun , Shahbazian Hajiehbibi , Hashemitabar Mahmoud , Fanaei Seyed Ahmad , Khorsandi Layasadat
Published: April 2022

Background: Medullary thyroid cancer (MTC) is a rare type of neuroendocrine tumor. This study aimed to investigate the gene and protein expression of RAP1GAP and DNA methylation patterns of its CpG74a , CpG74b , and CpG24 in an Iranian population with MTC. Methods: In this case-control study, we selected 55 individuals who underwent thyroidectomy in Erfan hospital, Tehran, between 2018 and 2020. Samples were divided into normal thyroid tissues (control; n=20), benign nodule (n=20), and MTC (n=15). DNA methylation patterns were investigated using MSP (methylation-specific PCR). The protein level and mRNA expression of RAP1GAP were also evaluated using western blotting and real-time PCR, respectively. Results: The hyper-methylation rates of CpG24 and CpG74a in the MTC samples were considerably higher than the controls (83% versus 15% and 74% versus 17%, respectively; P<0.001). The methylation/unmethylation ratio of CpG74a , and CpG24 was considerably higher than the controls (P<0.001). The methylation/unmethylation ratio of CpG24 in the benign nodules was also considerably greater than the controls (P<0.001). The mRNA expression and the protein level of RAP1GAP in the MTC group were considerably lower than the controls (P=0.005 and P=0.035, respectively). In the MTC group, aberrant methylation of CpG74a and CpG24 was significantly correlated with decreasing expression of the Rap1Gap gene (R2 : 0.23; P=0.032 and R2 : 0.56; P=0.001, respectively). Conclusion: Hyper-methylation in CpG24 and CpG74a and decreasing expression of RAP1GAP can be considered as diagnostic biomarkers for MTC.
Description of a peasant abode in the patois of the hamlet of Borbushino
Authors: Ilyina Elena N.
Published: April 2022

The article focuses on the description of the rustic dwelling as the basis of material culture in the world view of the inhabitants of Lake Beloye (White Lake) surroundings. Recordings of speech of residents of the hamlet of Borbushino of Kirillov district of Vologda Region serves as research material, Those were obtained by this paper's author in the course of conversations on the programme "Lexical Atlas of the Russian Folkish Patois" in the dialectological expeditions of 1988 – 2021. The subject of the analysis of this paper includes the common names of the space where household outbuildings and crops of one peasant family were located; as well as the living quarters and their parts, fixtures and fittings, stove heating, household outbuildings, religious buildings in the settlement itself and in its surroundings; all mentioned in folkish stories scrupulously precise and yet with elements of self-analysis; that can also give an idea of the features of spiritual world, identification "friend or foe" of the north Russian peasants. Information on the peasant dwelling vocabulary obtained through conversations with the inhabitants of the study area, is systematised on the basis of a similar theme in modern regional linguistics of the consolidated system of Russian dialects, as well as patois of separate territories. The conclusion was made that the change of the character of the villagers' labour activity had inevitably entailed the restructuring of the space of both rural Russia as a whole and an individual peasant homestead.
Subject-speech organisation of Vladimir Kornilov's short story “Cone Picker”
Authors: Fokina Madina A.
Published: April 2022

The article presents a philological analysis of the linguistic means that determine the originality of the subject-speech organisation of the story written by Vladimir Kornilov, Kostroma prose writer of the second half of the 20th century. The purpose of the study is to identify the structural-semantic and pragmatic properties ofthe language units that form the speech plans of the primary narrator and the main character acting as a storyteller. The article analyses the leading language techniques and means of colloquial speech stylization – dialogisation of a monologue word; the use of colloquial and dialect vocabulary, Russian proverbs; folk interpretations of the semantics of words. Kostroma dialect words are involved in the creation of the character's speech portrait and reflect regional cultural and linguistic features. The article examines the key metaphorical images created by the lexical and syntactic language units. It also studies the comparative figures of speech that reveal the dialectical unity of nature and human. Rhetorical questions and aphoristic phrases of the narrator serve as expressive characteristics of the events and actions of the characters. The author of the article elaborates on the fragments of the tale narration in which the main idea of the story and the author's point of view are expressed. The pragmatic potential of the language units is manifested in their active influence on the structural and content organisation offictional narration. The lexical dominants ‘deed’ and ‘concord’ unite the separate compositional parts of the story into a common narrative space and actualise the philosophical meaning of the short story. The interaction of the primary narrator’s speech and the storyteller’s speech forms a two-voiced narration, creating textual polyphony. As a result of the study of the linguistic features of Vladimir Kornilov's short story, the author of the article brings into focus a system of language means and stylisation techniques that determine the originality of the subjective organisation of the narrative, explicate the conceptual content of the text and ensure its structural and semantic unity.
Museum-organising activities of the People's Commissariat of Education in Ivanovo-Voznesensk province in 1918–1920
Authors: Vinogradova Yulia A. , Okolotin Vladimir S.
Published: April 2022

The article is devoted to the study of the activities of public education bodies in organising the work of museums on the territory of the newly formed Ivanovo-Voznesensk Province in the early years of the Soviet state. Using the example of museums in Kineshma and Ivanovo-Voznesensk, the main problems they had faced, were considered. The importance and relevance of museums for educational purposes is revealed not only for the centre of the province, but also for lesser towns. Examples from the practice of collecting historical, cultural, artistic and museum values in the estates of industrialists and entrepreneurs, the asceticism of the first museum workers are given. The article uses documents from the State Archive of Ivanovo Region and the auxiliary fund of Kineshma Art and Historical Museum, a significant part of which has been introduced into scientific circulation for the first time. It is addressed to researchers studying the actions of the executive authorities of the Soviet state in its early years of formation and development, as well as the scientific community.
Pengaruh Corporate Social Responsibility, Keputusan Investasi, dan Kebijakan Dividen Pada Perusahaan dengan Profitabilitas Sebagai Variabel Moderasi
Authors: Yulli Yolla Rahmi
Published: April 2022

Penelitian ini bertujuan untuk menjelaskan pengaruh corporate social responsibility, keputusan investasi dan kebijakan dividen terhadap nilai perusahaan dengan profitabilitas sebagai variabel moderasi. Corporate Social Responsibility, Keputusan Investasi dan Kebijakan Dividen digunakan sebagai variabel independen dan Nilai Perusahaan digunakan sebagai variabel dependen. Serta Profitabilitas sebagai variabel moderasi. Penelitian ini dilakukan pada perusahaan manufaktur yang terdaftar di Bursa Efek Indonesia (BEI) tahun 2016-2020 yang berjumlah sebanyak 193 perusahaan. Data diperoleh dengan mengakses halaman Bursa Efek Indonesia. Cara penentuan sampel dalam penelitian ini menggunakan metode purposive sampling sehingga di dapat jumlah sampel sebanyak 50 perusahaan. Data pada penelitian ini di analisis dengan teknik analisis regresi data panel. Hasil penelitian menunjukkan bahwa Corporate Social Responsibility berpengaruh positif dan tidak signifikan terhadap Nilai Perusahaan. Keputusan Investasi berpengaruh positif dan signifikan terhadap Nilai Perusahaan. Kebijakan Dividen berpengaruh positif dan signifikan terhadap Nilai Perusahaan. Kepemilikan Manajerial, Kepemilikan Institusional dan Struktur Aktiva berpengaruh positif dan signifikan terhadap Struktur modal. Corporate Social Responsibility berpengaruh positif dan signifikan terhadap Nilai Perusahaan dengan Profitabilitas sebagai variabel moderasi. Keputusan Investasi berpengaruh positif dan signifikan terhadap Nilai Perusahaan dengan Profitabilitas sebagai variabel moderasi. Kebijakan Dividen berpengaruh positif dan signifikan terhadap Nilai Perusahaan dengan Profitabilitas sebagai variabel moderasi.
Struktur Modal,Kepemilikan Institusional dan Investment Opportunity Set (Ios) terhadap Kualitas Laba dengan Voluntory Disclosure Sebagai Variabel Intervening
Authors: Lova Mutiara
Published: April 2022

Penelitian ini bertujuan untuk mengetahui pengaruh struktur modal, kepemilikan institusional dan investment opportunity set (ios) terhadap kualitas laba dengan voluntory disclosure sebagai variabel intervening pada perusahaan manufaktur sektor industri yang terdaftar di bursa efek indonesia periode 2016-2020. Sampel dalam penelitian ini berjumlah 40 perusahaan manufaktur sektor industri dengan periode penelitian 5 tahun. Metode analisis yang digunakan dalam penelitian ini adalah analisis regresi data panel dengan hasil Estimasi Fixxed Effect dengan menggunakan Eviews 10.Hasil penelitian ini   menunjukan   bahwa   struktur   modal tidak berpengaruh signifikan terhadap kualitas laba dengan voluntory disclosure sebagai variabel intervening dan kepemilikan institusional dan investment opportunity set (ios) berpengaruh   signifikan   terhadap kualitas laba dengan voluntory disclosure sebagai variabel intervening.
Tax Avoidance Melalui Ukuran Perusahaan sebagai Variabel Moderasi : Kepemilikan Institusional, Intensitas Modal dan Umur Perusahaan
Authors: Putri Adinda Ardila
Published: April 2022

Tujuan penelitian ini adalah untuk menguji pengaruh kepemilikan institusional, intensitas modal dan umur perusahaan terhadap tax avoidance dengan ukuran perusahaaan sebagai variabel moderasi. Populasi dalam penelitian ini adalah perusahaan manufaktur yang terdaftar di Bursa Efek Indonesia tahun 2016-2020. Hasil penelitian ini menunjukkan bahwa kepemilikan institusional, intensitas modal dan umur perusahaan berpengaruh signifikan secara bersama-sama terhadap tax avoidance dengan ukuran perusahaan sebagai variabel moderasi. Secara parsial kepemilikan institusional berpengaruh positif dan signifikan terhadap tax avoidance. Intensitas modal dan umur perusahaan secara parsial berpengaruh negatif dan signifikan terhadap tax avoidance. Ukuran perusahaan sebagai variabel moderasi mampu memperkuat hubungan antara kepemilikan institusional dan intensitas modal terhadap tax avoidance. Sementara, ukuran perusahaan sebagai variabel moderasi memperlemah hubungan antara umur perusahaan terhadap tax avoidance.
Pengaruh Profitabilitas, Struktur Modal, Sales Growth, Pergantian Ceo Terhadap Financial Distress dengan Struktur Corporate Governance sebagai Variabel Moderasi
Authors: Wahyuni Risma Sri
Published: April 2022

Penelitian ini bertujuan untuk menganalisis pengaruh profitabilitas, struktur modal, sales growth, dan pergantian CEO pada financial distress dengan struktur corporate governance sebagai ariable moderasinya. Populasi dalam penelitian ini adalah semua perusahaan manufaktur yang terdaftar di Bursa Efek Indonesia, dengan sampel sebanyak 63 perusahaan, periode penelitian dari tahun 2016 sampai dengan 2020. Hasil analisis penelitian ini diperoleh (1) Profitabilitas berpengaruh positif dan signifikan terhadap financial distress (2) Struktur modal berpengaruh ariable dan signifikan terhadap financial distress (3) Sales growth tidak berpengaruh terhadap financial distress (4) pergantian CEO berpengaruh ariable dan signifikan terhadap financial distress (5) struktur corporate governance berpengaruh ariable dan signifikan terhadap financial distress (6) struktur corporate governance mampu memperkuat pengaruh profitabilitas terhadap financial distress (7) struktur corporate governance tidak mampu memoderasi pengaruh struktur modal terhadap financial distress (8) struktur corporate governance tidak mampu memoderasi pengaruh sales growth terhadap financial distress (9) struktur corporate governance tidak mampu memoderasi pengaruh pergantian CEO terhadap financial distress.
Profitabilitas, Ukuran Perusahaan, dan Komite Audit pada Audit Delay yang Dimoderasi oleh Reputasi Kap
Authors: Sari Lora Yuspita
Published: April 2022

Penelitian ini bertujuan untuk menguji profitabilitas, ukuran perusahaan dan komite audit terhadap audit delay dengan reputasi KAP sebagai variabel moderasi pada Perusahaan Manufaktur yang terdaftar di Bursa Efek Indonesia tahun 2016-2020. Teknik pemilihan sampel menggunakan porpusive sampling dan didapatkan sebanyak 52 Perusahaan manufaktur. Teknik analisis data menggunakan analisis regresi moderasi menggunakan Eviews 10.0. Berdasarkan hasil uji hipotesis profitabilitas tidak berpengaruh signifikan terhadap audit delay. Ukuran perusahaan berpengaruh siginifikan terhadap audit delay. Komite audit tidak berpengaruh signifikan terhadap audit delay. Profitabilitas tidak berpengaruh signifikan terhadap audit delay dengan reputasi kap sebagai moderasi dan Reputasi KAP mampu memperlemah pengaruh antara profitabilitas terhadap audit delay. Ukuran perusahaan berpengaruh positif dan signifikan terhadap audit delay dengan reputasi kap sebagai moderasi dan Reputasi KAP mampu memperlemah pengaruh antara Ukuran perusahaan terhadap audit delay. Komite audit berpengaruh negatif dan signifikan terhadap audit delay dengan reputasi kap sebagai moderasi dan Reputasi KAP mampu memperkuat pengaruh antara komite audit terhadap audit delay pada Perusahaan Manufaktur yang terdaftar di Bursa Efek Indonesia tahun 2016-2020. Diharapkan penelitian ini dapat membantu perusahaan tidak hanya perusahaan Manufaktur namun juga perusahaan lain yang ada di Indonesia untuk meningkatkan Audit Delay dengan mempertimbangkan faktor-faktor yang berpengaruh signifikan terhadap Audit Delay tersbeut seperti Profitabilitas, Ukuran Perusahaan, dan Komite Audit, serta peningkatan Reputasi KAP.
Pengaruh Akuntabilitas, Transparansi, dan Pengawasan terhadap Kinerja Instansi Pemerintah dengan Pemanfaatan Accounting Information System sebagai Pemoderasi
Authors: Ambarwati Ambarwati
Published: April 2022

Penelitian ini bertujuan untuk menguji pengaruh akuntabilitas, transparansi, dan pengawasan terhadap kinerja instansi pemerintah dengan pemanfaatan accounting information system sebagai variabel moderating. Penelitian ini merupakan penelitian kuantitatif dengan pendekatan deskriptif. Populasi dalam penelitian ini adalah seluruh pegawai yang bekerja di BPKAD di Kota Padang. Teknik pengambilan sampel menggunakan metode purposive sampling. Sampel di dalam penelitian ini adalah pegawai yang bekerja pada BPKAD Kota Padang dengan ketentuan bahwa responden yang bersangkutan minimal telah bekerja selama satu tahun pada BPKAD Kota Padang tersebut, adapun sampel dalam penelitian ini berjumlah 56 pegawai. Hasil penelitian menunjukkan bahwa akuntabilitas berpengaruh negatif terhadap kinerja instansi pemerintah, transparansi dan pengawasan berpengaruh positif terhadap kinerja instansi pemerintah. Analisis variabel moderating dengan pendekatan uji interaksil menunjukkan bahwa pemanfaatan accounting information system tidak memoderasi akuntabilitas, transparansi, dan penggawasan terhadap kinerja instansi pemerintah.
Okul Psikolojik Danışmanlarında Özgecilik ile Zenofobi Arasındaki İlişkide Mültecilere Karşı Duygusal Mesafenin Aracı Rolü
Authors: ÖZYURT Songül , ÜMMET Durmuş
Published: April 2022

2011 yılında Suriye’de başlayan iç karışıklıklar ve savaş sonrasında Suriye’den Türkiye’ye göç başlamıştır ve şu an Türkiye’de yaklaşık 3.5 milyon Suriyeli bulunmaktadır. Eğitim sistemi içinde ise büyük oranda Suriyeli öğrenci eğitim görmektedir. Bu çalışmada okul psikolojik danışmanlarının özgecilik ile zenofobi özellikleri arasındaki ilişkide mültecilere karşı hissettikleri duygusal mesafenin aracı rolünün araştırılması amaçlanmaktadır. Bu amaç doğrultusunda rastgele seçilen 326 okul psikolojik danışmanından veri toplanmıştır. Araştırmanın amacına yönelik olarak yapılan istatistiksel analizler sonucunda özgecilik (bağımsız değişken), zenofobi (bağımlı değişken) ve duygusal mesafe (aracı değişken) arasında anlamlı ilişki olduğu belirlenmiştir. Aracılık analizlerine göre, özgecilik ile zenofobi arasındaki anlamlı ilişki modele duygusal mesafe değişkeni dâhil olunca ortadan kalkmıştır. Bu yüzden modelde duygusal mesafe değişkeni tam aracı role sahiptir.
FILSAFAT MATEMATIKA: KEDUDUKAN, PERAN, DAN PERSEPEKTIF PERMASALAHAN DALAM PEMBELAJARAN MATEMATIKA
Authors: Sadewo Yosua Damas , Purnasari Pebria Dheni , Muslim Suyitno
Published: April 2022

Tujuan dari penelitian ini adalah untuk memberikan kajian secara mendetail terhadap filsafat matematika, relasi filsafat matematika dengan pembelajaran, serta mengungkap problem dalam pembelajaran matematika dari perspektif filsafat matematika. Metode penelitian yang digunakan adalah metode penelitian kualitatif dengan pendekatan literatur review yakni dengan melakukan kajian terhadap beberapa artikel yang berbicara mengenai filsafat matematika serta problem-problem dalam pembelajaran matematika. Berdasarkan hasil penelitian dapat disimpulkan bahwa filsafat matematika merupakan refleksi terhadap ilmu matematika itu sendiri sekaligus mempertegas makna dari suatu kebenaran dalam matematika. Cakupan dalam filsafat matematika dapat dikategorikan ke dalam 4 cabang ilmu yakni epistemologi matematika, ontologi matematika, metodologi matematika, dan logika matematika. Ditinjau dari filsafat matematika, pelaksanaan pembelajaran yang terdiri dari input, process, dan output tidak bisa lepas dari peran dan kedudukan filsafat matematika. Kendala dalam pelaksanaan pembelajaran dapat diakibatkan karena tidak tersambungnya peran dari ilmu filsafat matematika dalam proses pembelajaran.
Evaluasi Satellite Precipitation Product (GSMaP, CHIRPS, dan IMERG) di Kabupaten Lampung Selatan
Authors: Pratama Alvin , Agiel Hayim Muhammad , Oktaviana Ade Ayu
Published: April 2022

The availability of rainfall data is an important requirement in various activities. The limitations of observational data make the satellit precipitation product (SPPs) as an alternative. However, the data must be verified before being used. Verification methods are done by using matric statistic methods such as correlation, error and relative bias. Meanwhile, to see the ability of SPPs in detecting rainfall events, it uses a contingency table method. The purpose of this research is to evaluate the ability of SPPs against observation data. Evaluation of SPPs rainfall data is carried out based on a time scale, namely monthly, 10 daily, and daily.  This research uses the data from 2018–2020. On a monthly and 10 daily scale, the CHIRPS data shows excellent linearity and rain detection ability. On a daily scale, IMERG shows better linearity than GSMaP and CHIRPS in every season, with moderate to strong correlation coefficients. However, these data tend to be underestimated with a very large bias. In terms of detecting daily rain, GSMaP tends to be better than CHIRPS and IMERG on every season based on the CSI index. However, in the dry season and transition II, the ability tends to be lower. In general, for the amount of rainfall intensity, the three SPPs data still has a fairly large error against the observation data eventhough the ability to detect rainfall is good.
Distribusi spasial kualitas perairan dan hubungannya dengan aktifitas budidaya perikanan di Teluk Lampung
Authors: Prasetyo Budhi Agung , Muawanah Muawanah , Mardianto Lutfi , Lubis Muhammad Zainuddin
Published: April 2022

Coastal water is water areas that receive much input of organic matter originating from human activities on land. Anthropogenic activities such as marine aquaculture in Teluk Lampung impact water quality on that waters. This study was conducted to determine the distribution of water quality around Teluk Lampung and its correlations to marine aquaculture activities. The analysis carried out in this study is spatial analysis to determine the spatial distribution of water quality in three focus area, namely Teluk Hurun (HB), Selatan Teluk Hurun (SHB) dan Pantai Sari Ringgung (SRB) as part of Teluk Lampung. In addition to spatial analysis, principal component analysis (PCA) was also carried out to determine water quality as a variable and its correlation to each area. Based on the results of this study, the spatial distribution of water quality varies based on the human activities type in each area. Based on the results of principal component analysis, it is known that the variability of several water quality variables also correlates with the human activities types, such as marine aquaculture and beach tourism.
Evaluasi Penyimpanan Obat di Gudang Farmasi Puskesmas Mangunsari Kota Salatiga
Authors: Dewi Vionica Citra , Yuswantina Richa
Published: April 2022

Drug storage is a pharmaceutical job in which the activities of regulating pharmaceutical supplies according to predetermined requirements are accompanied by an information system that always guarantees the availability of pharmaceutical supplies. The purpose of this study was to get an overview of drug storage and to know the evaluation of drug storage in the pharmacy warehouse of the Mangunsari Health Center in Salatiga city based on the Minister of Health Regulation No. 74 of 2016. The research design used a descriptive method with observations of the research object and direct interviews. Collecting data by filling out the check list sheet indicators based on the results of observations and interviews. The data is presented in the form of a check list table and then analyzed by comparing the drug storage indicators with the actual situation. The results of this study show that the percentage of storage parameters for warehouse requirements is 92.8%, the percentage of drug storage parameters is 100%, and the percentage of storage parameters for the stok card recording system is 100%. Based on the results of the research on evaluation of drug storage in the warehouse of the Mangunsari Health Center, Salatiga City, it is in accordance with Minister of Health Regulation No. 74 of 2016 on drug storage parameters and stok card recording systems.

ABSTRAK

Penyimpanan obat merupakan pekerjaan kefarmasian dimana kegiatan pengaturan pembekalan farmasi menurut persyaratan yang telah ditetapkan disertai dengan sistem informasi yang selalu menjamin ketersediaan perbekalan farmasi. Tujuan pada penelitian ini untuk mendapatkan gambaran penyimpanan obat dan mengetahui evaluasi penyimpanan obat di gudang farmasi Puskesmas. Desain penelitian menggunakan metode deskriptif dengan pengamatan terhadap objek penelitian dan wawancara langsung. Pengumpulan data dengan cara mengisi indikator lembar chek list berdasarkan hasil pengamatan dan wawancara. Data disajikan dalam bentuk tabel chek list kemudian dianalisa dengan cara membandingkan indikator penyimpanan obat dengan keadaan sebenarnya. Hasil penelitian ini menunjukkan gambaran bahwa persentase parameter penyimpanan persyaratan gudang 92,8% persentase parameter penyimpanan obat 100%, dan persentase parameter penyimpanan sistem pencatatan kartu stok 100% Berdasarkan hasil penelitian evaluasi penyimpanan obat di gudang Puskesmas Mangunsari Kota Salatiga sudah sesuai dengan Permenkes No 74 Tahun 2016 pada parameter penyimpanan obat dan sistem pencatatan kartu stok.