bluuebunny/crossref_metadata_2025 huggingface dataset:
How I Manage Cancer-Associated Thrombosis
Authors: Moik Florian , Ay Cihan
Published: January 2020

In this concise review, we discuss some common clinical challenges in the management of patients with cancer-associated venous thromboembolism (VTE), a frequent complication in patients with cancer that increases morbidity and mortality. While direct oral anticoagulants (DOACs) have been established in clinical practice for anticoagulation in patients with VTE without cancer, their efficacy and safety in patients with cancer have not been assessed in randomized controlled trials until recently. The choice of the appropriate anticoagulant agent in the era of DOACs to treat patients with cancer-associated VTE is based on balancing the risk of recurrence against the risk of bleeding, and potential drug–drug interactions. However, the management of patients is challenged by special scenarios such as incidentally diagnosed pulmonary embolism and catheter-related thrombosis, and sometimes complicated by concomitant thrombocytopenia. We provide guidance for management of cancer-associated VTE in different clinical scenarios in a case-based manner and briefly review recent clinical studies and guidelines to explain our approach to management of the cases.
Potential function of the Wilson-Racah quantum system
Authors: Taiwo T. J.
Published: January 2020

We show how to establish a correspondence between the recently introduced formulation of quantum mechanics based on orthogonal polynomials in the energy and physical parameters (without reference to a potential function) and the convention formulation. In this work, we obtain the potential function for the newly introduced quantum system associated with the Wilson and Racah polynomials [A. D. Alhaidari and T. J. Taiwo, J. Math. Phys. 58, 022101 (2017)] using any of the proposed procedures in the work of Alhaidari [Commun. Theor. Phys. 68, 711 (2017)]. To achieve that, we use the matrix elements of the potential function and the basis in which these were calculated.
Semiclassical WKB problem for the non-self-adjoint Dirac operator with analytic potential
Authors: Fujiié Setsuro , Kamvissis Spyridon
Published: January 2020

In this paper, we examine the semiclassical behavior of the scattering data of a non-self-adjoint Dirac operator with analytic potential decaying at infinity. In particular, employing the exact WKB method, we provide the complete rigorous uniform semiclassical analysis of the reflection coefficient and the Bohr–Sommerfeld condition for the location of the eigenvalues. Our analysis has some interesting consequences concerning the focusing cubic nonlinear Schrödinger (NLS) equation in view of the well-known fact discovered by Zakharov and Shabat that the spectral analysis of the Dirac operator is the basis of the solution of the NLS equation via inverse scattering theory.
Identification of Colombian coffee price dynamics
Authors: Rodríguez Angie , Melgarejo Miguel
Published: January 2020

The daily Colombian coffee price is a chaotic signal that has emerged from a complex economic system. This work proposes to identify its dynamics by means of two models: a single multiscroll Chua system and the coupling of two of these systems. Models are fine-tuned through an artificial bee colony optimization algorithm. Results show that this approach can reconstruct the price signal in terms of several statistics and points out a way for its long-term forecasting.
Experimental investigation of reciprocity of temperature response across two layer samples by flash method
Authors: Baba Takahiro , Baba Tetsuya , Mori Takao
Published: January 2020

The reciprocity of heat transfer is a fundamental principle. However, there are few experimental studies to verify this principle. In this paper, we measured two layer samples made of ordinary metal by the laser flash method to verify the reciprocity principle. We heated and detected the different surfaces of each two layer sample to observe the reciprocal response. We also made use of areal heat diffusion time to analyze the temperature rise of two layer samples to enable to extend analysis for future multi-layer samples. This study is an important starting point to discuss whether characteristic materials obey the reciprocal principle.
FCHL revisited: Faster and more accurate quantum machine learning
Authors: Christensen Anders S. , Bratholm Lars A. , Faber Felix A. , Anatole von Lilienfeld O.
Published: January 2020

We introduce the FCHL19 representation for atomic environments in molecules or condensed-phase systems. Machine learning models based on FCHL19 are able to yield predictions of atomic forces and energies of query compounds with chemical accuracy on the scale of milliseconds. FCHL19 is a revision of our previous work [F. A. Faber et al., J. Chem. Phys. 148, 241717 (2018)] where the representation is discretized and the individual features are rigorously optimized using Monte Carlo optimization. Combined with a Gaussian kernel function that incorporates elemental screening, chemical accuracy is reached for energy learning on the QM7b and QM9 datasets after training for minutes and hours, respectively. The model also shows good performance for non-bonded interactions in the condensed phase for a set of water clusters with a mean absolute error (MAE) binding energy error of less than 0.1 kcal/mol/molecule after training on 3200 samples. For force learning on the MD17 dataset, our optimized model similarly displays state-of-the-art accuracy with a regressor based on Gaussian process regression. When the revised FCHL19 representation is combined with the operator quantum machine learning regressor, forces and energies can be predicted in only a few milliseconds per atom. The model presented herein is fast and lightweight enough for use in general chemistry problems as well as molecular dynamics simulations.
Investigation of ion acceleration effect influence on formation of ambipolar potential profile in the expander region
Authors: Abramov I. S. , Gospodchikov E. D. , Shaposhnikov R. A. , Shalashov A. G.
Published: January 2020

This paper presents a study of plasma flux characteristics flowing out from the gas-dynamic mirror trap along the magnetic field lines to a metal wall. The main feature of the current work is that the effect of ion acceleration by ambipolar potential is considered in the expander region. The developed model also takes into account a possibility of transition from the collisional expansion of electron flow in the vicinity of the magnetic plug to the collisionless regime. The developed model allows calculation of the ambipolar potential profile and plasma characteristics in the expander region.
Non-contact localized probing of ferroelectric phase transitions in Li+/Er3+:BaTiO3 ceramics using fluorescence abnormalities
Authors: Li Jiaming , Sun Enwei , Tang Lingli , Zhou Yuan , Li Leipeng , Miao Jipeng , Zhang Zhiguo , Cao Wenwu
Published: January 2020

Fluorescence abnormalities associated with the ferroelectric phase transition of Li+/Er3+:BaTiO3 (BLET) ceramics were studied based on photoluminescence (PL) spectra. Sharp changes were found in the integrated intensities, peak intensities, and fluorescence intensity ratios of both upconversion spectra (2H11/2/4S3/2−4I15/2) and downconversion infrared spectra (4I13/2−4I15/2) around the ferroelectric-paraelectric phase transition temperature in BLET ceramics under the excitation of a 980 nm laser. All changes happened within the temperature interval of 126 °C–130 °C. The relative changing rate (RCR) was adopted to quantitatively describe this structure-sensitive PL. For the system under study, the maximum RCR occurs for the PL peak intensity at 542.7 nm.
A model-free analysis of configurational properties to reduce the temperature- and pressure-dependent segmental relaxation times of polymers
Authors: Zhao Xiao , Simon Sindee L.
Published: January 2020

The segmental relaxation time data for poly(vinyl acetate), poly(vinyl chloride), and linear and star polystyrene are analyzed using a model-free method to determine how the temperature- and pressure-dependent relaxation times, τ, scale with the relative configurational thermodynamic properties. The model-free method assumes no specific mathematical form, such as reciprocal linearity, and the configurational properties are referred to an isochronal state to eliminate the bias associated with the definition of the ideal glassy state. The scaling ability of a given configurational property is strongly material-dependent with the logarithm of τ scaling better with TSc and Hc for poly(vinyl acetate), with TSc, Hc, and Uc for poly(vinyl chloride), and with TSc, Hc, and Vc for linear and star polystyrene. The choice of the isochronal reference state does not qualitatively affect the results.
Control of dynamics via identical time-lagged stochastic inputs
Authors: Bolhasani Ehsan , Azizi Yousef , Abdollahpour Daryoush , Amjad Jafar M. , Perc Matjaž
Published: January 2020

We investigate the impact of a stochastic forcing, comprised of a sum of time-lagged copies of a single source of noise, on the system dynamics. This type of stochastic forcing could be made artificially, or it could be the result of shared upstream inputs to a system through different channel lengths. By means of a rigorous mathematical framework, we show that such a system is, in fact, equivalent to the classical case of a stochastically-driven dynamical system with time-delayed intrinsic dynamics but without a time lag in the input noise. We also observe a resonancelike effect between the intrinsic period of the oscillation and the time lag of the stochastic forcing, which may be used to determine the intrinsic period of oscillations or the inherent time delay in dynamical systems with oscillatory behavior or delays. As another useful application of imposing time-lagged stochastic forcing, we show that the dynamics of a system can be controlled by changing the time lag of this stochastic forcing, in a fashion similar to the classical case of Pyragas control via delayed feedback. To confirm these results experimentally, we set up a laser diode system with such stochastic inputs, which effectively behaves as a Langevin system. As in the theory, a peak emerged in the autocorrelation function of the output signal that could be tuned by the lag of the stochastic input. Our findings, thus, indicate a new approach for controlling useful instabilities in dynamical systems.
DNA hybridization helps protein-mediated cell adhesion for tissue engineering
Authors: Bandari Anashe
Published: January 2020

Ensuring cell adhesion is an important aspect of artificial tissue engineering but can be difficult to mediate without natural cell adhesion molecules.
A pragmatics of intimacy
Authors: Márquez Reiter Rosina , Frohlich David M.
Published: January 2020

This study examines the ways in which multiple modern communication technologies facilitate, across time and space, the maintenance of a close interpersonal relationship between two best friends. The analysis, which focuses mainly on the openings and closings of the different types of communications, reveals a tendency for the friends to shorten openings and extend closings. However, this is possible only if the friends are fully aware of, and care about, the practical, social and emotional details of each other’s lives during periods of absence. The concomitant linguistic behaviours in their interpersonal interactions could be described as a kind of pragmatics of intimacy which cannot be achieved without the explicit and practical demonstration of that mutual care and concern.
Autophagy promotion enhances the protective effect of Morroniside on human OA chondrocyte
Authors: Xiao Zhanhao , Wang Jiankun , Chen Sunyu , Feng Yang
Published: January 2020

Morroniside plays a therapeutic role in knee osteoarthritis (OA) by protecting chondrocytes. PI3K/AKT signaling is involved in the regulation of chondrocytes by Morroniside. PI3K/AKT suppresses autophagy through downstream signaling. However, the regulation of chondrocyte autophagy by Morroniside and the significance of the above effect on protecting chondrocytes aren’t clear. The results showed that Morroniside inhibited the autophagiy of human OA chondrocytes. Besides, both PI3K inhibitors and mTOR inhibitors significantly reversed the autophagy reduced by Morroniside, but had no effect on the protective effect of Morroniside on chondrocytes. However, the enhanced autophagy caused by overexpression of autophagic genes enhanced the protective effect of Morroniside on chondrocytes. In conclusion, Morroniside represses the autophagy of human OA chondrocyte, which is related to PI3K/mTOR pathway. Moreover, the upregulation of autophagy further promoted the role of Morroniside in treating chondrocytes. Our data present a potential clue for the therapeutic strategies of Morroniside in treating OA.
Suppression of NSDHL attenuates adipogenesis with a downregulation of LXR-SREBP1 pathway in 3T3-L1 cells
Authors: Zhang Haiyan , Li Chengping , Xin Youzhi , Cui Xiao , Cui Jianwei , Zhou Guoli
Published: January 2020

Previous RNA-Seq analyses revealed that NAD(P)H steroid dehydrogenase-like (NSDHL) has a different expression during 3T3-L1 differentiation; however, its roles in adipogenesis are unknown. In the present study, using quantitative real-time PCR, we confirmed that NSDHL knockdown increased the proliferation of 3T3-L1 preadipocytes, but attenuated the differentiation of 3T3-L1 preadipocytes, as evidenced by reduced lipid accumulation and down-regulation of PPARγ gene expression. Further analyses showed that the expression peak of NSDHL was at the early stage of 3T3-L1 preadipocytes differentiation and LXR-SREBP1 signaling pathway was downregulated in NSDHL-knockdown 3T3-L1 cells. Collectively, our findings indicate that NSDHL is a novel modulator of adipogenesis. Moreover, our data provide insight into the complex relationships between sterol sensing, LXR-SREBP1 signaling pathway, and PPARγ in 3T3-L1 cells.
Quantum field representation of photon-molecule interactions
Authors: Bradshaw David S , Forbes Kayn A , Andrews David L
Published: January 2020

In reporting and explaining the interactions of light with atoms and molecules, a photon-based description is not only appropriate but clearly essential when electronic or other kinds of quantum transition ensue. However, textbook treatments frequently go no further than the Planck relation, in representing the quantum nature of the light itself—often resorting to classical principles when discussing mechanism. Complete consistency and rigour can be achieved by treating both the matter and the radiation in a fully quantised form, which requires the electromagnetic fields to be cast in a quantum field representation. It proves possible to develop a rigorous approach to this theory that is simple to convey and apply, and which lends itself to a significantly enhanced level of appreciation of mechanism. This paper lays a concise foundation and exemplifies the application in three specific cases: absorption, emission and scattering. It is also shown how this formulation affords a basis for applications in higher-order, multiphoton and nonlinear optical processes.
Ptychographic phase retrieval by proximal algorithms
Authors: Yan Hanfei
Published: January 2020

We derive a set of ptychography phase-retrieval iterative engines based on proximal algorithms originally developed in convex optimization theory, and discuss their connections with existing ones. The use of proximal operator creates a simple frame work that allows us to incorporate the effect of noise from a maximum-likelihood (ML) principle. We focus on three particular algorithms, namely proximal minimization, alternating direction method of multiplier and accelerated proximal gradient (APG). We benchmark their performance with numerical simulations, and discuss their optimal conditions for convergence and accuracy. An experimental dataset is used to demonstrate their effectiveness as well, in which case an array of cubic Au nanoparticles with a size of 50 nm is imaged. We show that with the presence of Poisson noise, a dataset with photon counts up to 104 at one detector pixel already requires ML-based methods to achieve a stable convergence. Among the three algorithms derived in this work, APG method is reported first time for its application in ptychographic reconstruction and shows superior performance in terms of both accuracy and convergence rate with a noisy dataset.
In silico optical control of pinned electrical vortices in an excitable biological medium
Authors: Majumder Rupamanjari , Zykov Vladimir S , Panfilov Alexander V
Published: January 2020

Vortices of excitation are generic to any complex excitable system. In the heart, they occur as rotors, spirals (2D) and scroll waves (3D) of electrical activity that are associated with rhythm disorders, known as arrhythmias. Lethal cardiac arrhythmias often result in sudden death, which is one of the leading causes of mortality in the industrialized world. Irrespective of the nature of the excitable medium, the rotation of a rotor is driven by its dynamics at the (vortex) core. In a recent study, Majumder et al (2018 eLife
7 e41076) demonstrated, using in silico and in vitro cardiac optogenetics, that light-guided manipulation of the core of free rotors can be used to establish real-time spatiotemporal control over the position, number and rotation of these rotors in cardiac tissue. Strategic application of this method, called ‘Attract-Anchor-Drag’ (AAD) can also be used to eliminate free rotors from the heart and stop cardiac arrhythmias. However, rotors in excitable systems, can pin (anchor) around local heterogeneities as well, thereby limiting their dynamics and possibility for spatial control. Here, we expand our results and numerically demonstrate, that AAD method can also detach anchored vortices from inhomogeneities and subsequently control their dynamics in excitable systems. Thus, overall we demonstrate that AAD control is one of the first universal methods that can be applied to both free and pinned vortices, to ensure their spatial control and removal from the heart and, possibly, other excitable systems.
A Computational Theory Study of Surface Plasmon Resonance (SPR) Porcine Gelatine Detected Sensor based-on Fe3O4 Nanoparticle—CNT with ATR Method in Kretschmann Configuration
Authors: Lutfiyah Maulina , Aji Eko Prabowo Wahyu , Melati Asih
Published: January 2020

Accurate biomolecular detection can be performed through the Surface Plasmon Resonance (SPR) phenomenon. This study was conducted to simulate the effect of the addition of Fe3O4 nanoparticle and Carbon Nanotube (CNT) in the Kretschmann and Otto configurations using porcine detection sensors. This study employs the equation of reflectance for the investigations of SPR properties (i.e. SPR angle and reflectance value) using Matlab software version 7.12.0. This research was used ATR method with Kretschmann configuration, He-Ne laser on wavelength 632.8 nm, semi-circle prism type BK7 and metal layer of gold nanoparticles. The results of this research can be used in the detection of porcine gelatine by Kretschmann configurations. The best thickness of the gold layer and Fe3O4 layer are 50 nm and 0.05 nm. Moreover, the thickness of SWCNT used is 15 nm. The applied SWCNT is more effective than MWCNT on porcine detection. The SWCNT material also proved to be better used in SPR systems.
Implementation of Go language to calculate ground state energy of atoms based on Density Functional Theory (DFT)
Authors: Gita Arisha Lafitiara , Alfianto Enggar , Rusydi Febdian
Published: January 2020

This study is using Go programming language that support parallel programming for numerical calculation. The program was created is designed for calculate ground-state energy of electron, which is based on Density Functional Theory (DFT). The basic mathematics of this program is using many basic concept of numerical mathematics (matrix calculation, Poisson solver, and standard routine of numerical mathematics).
Apparent Diffusion Coefficient of Diffusion Weighted Imaging have Strong Correlation with the Malignancy Grading of Intracranial Tumor
Authors: Sensusiati AD
Published: January 2020

Background and purpose: Accurate imaging diagnosis before surgery is fundamental to determine whether a tumor is benign or malignant. Diagnosis only from structural MRI is not specific. However, the diffusivity of the benign and malignant lesion is different and could be measured by ADC. The Apparent Diffusion Coefficient (ADC) values are calculated automatically by application software and displayed as a parametric map that reflects the degree of diffusion of water molecules through different tissues. The purpose of this study was to analyze the correlation between Diffusion-Weighted Magnetic Resonance Imaging (DWI) and Apparent Diffusion Coefficient (ADC) values with histopathology grading of brain tumors.

Material and methods: Pathology reports of intracranial tumor material were correlated with diffusivity of the tumor, and the ADC values, performed within 2 years of post-operative histopathology study. A freehand closed ROI out-lined the whole visible tumor on the most representative slice of ADC maps defined as the slice with the maximum diameter of the solid neoplastic component. ADC values were taken from 2 averages of 2 ROIs. Spearman Correlation test was used to assess the correlation between ADC values with the malignancy grading of the tumor.

Result: Low-grade malignant tumors show facilitated diffusion with high ADC values, and high-grade malignant tumors show restricted diffusion with low ADC values. The mean ADC value of Grade I tumor is 1.0799 ± 0.2356 x 10−3 mm2/sec and the mean ADC value of Grade IV tumor is 0.6798 ± 0.23729 x 10−3 mm2/sec. The Spearman correlation test between ADC value and histopathology result shown r = -0.536 and p=0.000 and the test result for ADC value and DWI shown r=-0.706 and p=0.000 (Sig. 0.05).

Conclusion: There was strong correlation between DWI and ADC values with histopathology grading of intracranial tumors.
Snedds (Self-nanoemulsifying Drug Delivery System) Formulation of Sarang Semut Extract on Cervical Cancer Cells (HeLa) with MTT Assay Method
Authors: Nugroho B H , Syifaudin M R , Fauzi L R , Anggraini E , Ritonga H O
Published: January 2020

Sarang semut (Myrcomedia pendans) is traditional medicine plant that has been widely used as alternative treatment for diabetics and cancer. Flavonoids in sarang semut ectract known as active copounds for pharmacology activity, and it has low solubility in water. The methods can be used to improve the availability of water-insoluble compounds for better to deliver the active compounds into the body is SNEDDS (Self –Nanoemulsifying Drug Delivery System). The purpose of this study is to get the formulation and characterized of SNEDDS of sarang semut. The parameters used were particle size, polydisperse index (PI), zeta potential. The results showed capryol 90 as oil vehicle, tween 80 as the surfactant, and propylene glycol as co-surfactant, and particle size is 12.53 nm, the polydisperse index is 0.27 Ð and value of zeta potential is -51, 43 mV. Physical stability of the three formula has shown good results. MTT Assay test results obtained with an amount of 258.755 ppm and 389.955 ppm are included in the range of toxic enough for IC50 is in the range ≤ 1000 ppm. The results obtained show that the sarang semut SNEDDS have good physical and chemical properties, has good organoleptic and have an inhibitory effect on the activity of Hela cells.
The Effect of Additive Substitute of MgO Nanoparticle on the Characteristics of Exports as Bone Filler
Authors: Izak Rudyardjo Djony , Wijayanto Setiawan
Published: January 2020

Research has been conducted on the effect of adding MgO nanoparticle additives to the characteristics of porous hydroxyapatite as bone filler. The purpose of this study was to optimize previous research by replacing the ZnO nanoparticle additive with MgO nanoparticles accompanied by the use of the injection method. Porous hydroxyapatite synthesis is carried out by mixing nano-sized hydroxyapatite powder with MgO nanoparticles and making PVA solution. The composition of MgO nanoparticles varied at 8 wt%, 10 wt%, 12 wt% and 14 wt%. The hydroxyapatite-MgO mixture is dissolved in PVA solution so that the hydroxyapatite slurry is formed. Polyurethane foam is prepared with dimensions of 1 cm × 1 cm × 1 cm. Hydroxyapatite slurry is injected into polyurethane foam and followed by thermal treatments. The thermal treatments process was carried out in 3 stages, the drying stage at 80ºC for 2 hours, the phase of removal of PVA and polyurethane foam by heating in a temperature of 650ºC for 1 hour, and the sintering stage at 1200ºC for 3 hours. The effect of variations in the addition of MgO nanoparticles additives to the porous hydroxyapatite produced was characterized using porosity test, compressive strength test, morphological test with SEM, functional group test with FTIR, and cytotoxicity test using MTT assay. Based on the analyzes that have been done, it is known that the porous hydroxyapatite sample with the addition of 14 wt% of the MgO nanoparticle additive shows the best character with a porosity percentage of 68.60%, compressive strength value of 2.43 MPa, pore size of 100.3 - 314.3 µm, and not toxic.
Enhancement of Dye Sensitized Solar Cell Efficiency Using Chlorophyll as Dye Sensitizer by Adding The SnO2Material to TiO2
Authors: Puspitasari Nurrisma , Rabi’atul Adawiyah Siti , Noer Fajar Muhammad , Yudoyono Gatut , Prajitno Gontjang , Rubiyanto Agus , Endarko
Published: January 2020

Dye-Sensitized Solar Cell (DSSC) is the third generation of solar cells. DSSC is formed by sandwich structure, there are five parts: ITO glass (Indium Tin Oxide) as the substrate; TiO2and SnO2as semiconductor material; natural dye from chlorophyll as an electron donor; gel electrolyte as electron transfer and active carbon as a catalyst in the counter electrode. The synthesis of nanometer-sized TiO2powder is obtained by coprecipitation method. The layer of TiO2was deposited on top of an ITO glass by doctor blade method. From the research, the DSSC efficiency has increased by nearly 100% after additions SnO2to TiO2. The DSSC efficiency result is 0.05% for DSSC before additions and 0.1% after additions
Design Monitoring Electrical Power Consumtion at Computer Cluster
Authors: Alfianto Enggar , Agustini Siti , Muharom Syahri , Rusydi Febdian , Puspitasari Ira
Published: January 2020

Electricity is one of the basic needs in the era of technological development, where all equipment must use electricity to operate such as computer, so that it requires a system that can monitor power consumption at computer cluster. To monitoring power consumption using WCS1800 to current sensor and microcontroller Atmega32 to data sensor process, and serial communication to send data to display at personal computer. From test system having two result, first is power consumption at computer cluster starting, where current value range is 0 to 38A with power consumption is 0 to 8360 watt. And second is power consumtion at computer cluster execution progran, current value is 27 to 40 A, with power consumption 5940 to 8800 watt. From this system has been design, the power consumption at computer cluster can be monitored and known value of energy consumption.
Analysis of Urban Points of Interest and Urban Traffic from Shenzhen Urban Space Optimization
Authors: Wang Yang , Xu Liquan
Published: January 2020

This paper is to discussing traffic accessibility and point of interest spatial network on the relationship between urban point of interest and the urban road network, First, we introduced the distribution of POI (points of interest, such as business, banking, catering, and attractions), and determining the road traffic and accessibility of cities through urban map data. Secondly, the spatial network formed by the POI is used to find the main factors, analyze the correlation between road traffic density and the road traffic density. Finally, the GIS platform is used for data organization for system analysis, mining urban data to obtain feature factors, and urban space optimization strategy. The studies results show urban POI affect road traffic through functional attributes, leading to changes in urban space.
Management by objectives: the Puerto Princesa Underground River, Palawan Philippines
Authors: Acero L
Published: January 2020

Puerto Princesa Underground River (PPUR) was proclaimed as national park in 1971 and included in the seven wonders of nature in 2012. It is located in the West coast of Palawan Philippines and north of Puerto Princesa City, Palawan Philippines. The underground river is the longest navigable river with a unique karst environment, home for endangered and endemic flora and fauna is a must see destination for tourists. Its management is unique, since it is manage by the city government and the Protected Area Management Board. The objective of this study is to describe and assess the activities done by the management in terms of its objectives as national park which is divided into three categories as; primary (genetic diversity, environmental services and tourism and recreation), secondary (scientific researches. Wilderness protection, and natural features and education) and tertiary (sustainable use). Documentary analysis, actual site immersion, interviews and focal group discussion were employed to gather pertinent data for this study. Result showed that the unique management of PPUR had done several activities in consonance with its objectives as national park. Activities done is geared on keeping the balance between community-driven protection and conservation of the park’s ecological integrity, its Outstanding Universal Value, and inclusive development through Transformative Tourism activities. Community empowerment had transformed the lives of residents in PPUR without prejudicing the environmental sustainability of the park.
Morphodynamics of river and coastal transport of sediments in mega delta basin, Niger Delta Nigeria
Authors: Okpara D A , Offiong M B
Published: January 2020

Niger delta is recognized as the third mega deltas in the history of mankind. Understanding the sediment dynamics and morphodynamics relationship between the morphology of the bedrocks to the hydrodynamic of its transport sediments is crucial for water bodies’ preservation, conservation, and sustainability. Sediments transportation in Niger delta involves a two-phase flow system in which one phase is considered to be fluid and the other phase is solid. The water bodies is seldom saturated with sediments occasioned by irregular solid waste dumps, erosions debris, and transported at ease without any form of management or control for many years now. Consequently, poor water resources, agriculture and fishery production are at extreme lost as sediment transport and deposition influences great magnitude of useful river dynamics. Therefore, the objective of this study is focused on whether sediment transport has an effect on the morphology of the channel in the Niger Delta basin. It is necessary to determine the relationship between these two key variables; Sediment yield and channel morphology. A correlation matrix was generated in MS Excel to determine the underlying relationship between the variables under study with a coefficient of determination of 11.23% and a positive correlation between suspended sediment yield, bed load and channel morphology of +0.345. The paper will be useful to research institutions, water resources agencies, government and environmental experts and engineers.
The curing characteristics and tear properties of phenolic resin on chloroprene rubber vulcanizate
Authors: Mayasari H E , Wirapraja A Y
Published: January 2020

Chloroprene rubber (CR) is synthetic rubber widely used for seal, joint, and also adhesive. For making rubber product, additives are needed and it can influence the properties of vulcanizates. This study aims to determine the curing characteristics and mechanical properties of chloroprene vulcanizate. The chloroprene vulcanizates were prepared by compounding with the two-roll mill and vulcanizing with the hydraulic press. Phenolic resin used as additives were varies i.e: 0, 10, 20, and 30 phr. The curing characteristics of the CR vulcanizates were studied by rheometer at 140 °C, 150 °C, and 160 °C. The tear properties of the CR vulcanizates were studied by tensile strength tester. The phenolic resin improves the mooney viscosity, scorch time and optimum curing time. The compound without phenolic resin gives the highest mooney viscosity and optimum curing time. The 10 phr phenolic resin give the best mooney viscosity, optimum curing time, constant rate, activation energy and also tear strength. The suitable curing temperature for CR compound is at 150 °C and the proper additive for CR vulcanizate is 10 phr phenolic resin.
An analysis of characteristic of Asphalt Pen 60/70 mixed with gilsonite additive
Authors: Kusuma Y , Fikri H , Sianturi F N M
Published: January 2020

The increase of the population growth in Indonesia causes an increase of the traffic volume on the road. With the increase of the traffic volume, it is necessary to improve the quality of the road construction, especially from the pavement layer quality. On the road that have moderate traffic volume to high traffic volume, several problems in the pavement layer are often found. One way to decrease the road damage is by improving the quality of the asphalt mixture, which means increasing the asphalt quality. The research design is conducted by testing the characteristic of Asphalt Pen 60/70 and also the Asphalt Pen 60/70 mixed with gilsonite additive at 4.5%; 5.5%; 6.5%; 7.5%; and 8.5% of the asphalt weight. The Asphalt Pen 60/70 mixed with the gilsonite additive is called as the modified asphalt. Based on the testing results, it is obtained that the characteristic of modified asphalt has a better asphalt characteristic than the Asphalt Pen 60/70. The percentage of gilsonite level that still meets all the modified asphalt requirements is at the percentage of 6.5% with ductility value >140 cm, 336°C flash point, 54.5°C softening point, 1.037 gravity specific, and 41 penetrations. Besides, the 7.5% and 8.5% gilsonite levels have better asphalt characteristic than the Asphalt Pen 60/70.
Analysis of bridge structure with non-linear time history method
Authors: Kamal R F , Gunadi R
Published: January 2020

Bridges in Indonesia, which built before the last standard SNI 2833:2016 was issued, need to be reviewed to ensure the safety against earthquakes. This study employs non-linear time history analysis as method to analyze and evaluate the bridge structure due to earthquake loads. The structure undergoes a test with earthquake loads from seven records of scaled acceleration ground motion. From the analysis result, scale adjustment of seven earthquakes records towards the target spectrum response demonstrates various effects on plastic joints scheme and earthquake damage values. The evaluation result based on Cisomang highway/toll-bridge analysis denotes that Response modification factor value (R) is within the limit of permitted value of SNI 2833:2016 standard.
Experimental study of bearing capacity pile foundation on peat soil by properties improvement using electrokinetic method and clamshell
Authors: Rabiya R , Syahril S , Somantri A K
Published: January 2020

Problem always arise when building infrastructure is located on peat soil, such as on a settlement bridge. To know this, an experimental test was conducted. From experimental testing, the PT00 model had the biggest drop at 87.16 mm, for the PT-25V model was 65.30 mm and the PT-KK-25V model amounted to 67.23 mm. For the model of PT00 experienced a faster settlement and small load is 37 kg, model PT-25V can withstand the load up to 49 kg, while for the model PT-KKK-25V, the pile foundation can afford the load up to 204 kg. The peat soil with pile foundation undergoes the fastest decrease of 52.25 mm on the PT-KKK-25V model. For PT00 and PT-25V models subjected to a smaller decrease process of 38.8 mm and 28.78 mm. The results of this analysis can be concluded that for the test pile foundation pressure. The aplication of improvement is more effective on the model PT-KKK-25V, namely pile foundation model is mixed 8% optimum contain of clamshell and electrokinetic with a voltage of 25V. However, for the pile foundation tensile testing, the application of modelling is more effective on the PT-25V type. Because electrokinetic can enlarge the tensile force of the pile foundation.
The 3-dimensional arcade game application of Khalid ibn al-Walid
Authors: Fathoni K , Nurhadi H A T , Hakkun R Y , Asmara R
Published: January 2020

Khalid ibn al-Walid was a hero of Islam who was very meritorious and inherited many exemplary values, namely sincerity, struggle and intelligence. But many people don’t know this hero. This is due to the widely available media introduction of Khalid ibn al-Walid figures such as history books and comic books that are less interesting. This can be overcome by developing an interactive historical game Khalid ibn al-Walid. This game is built with 3D characters using the arcade genre and the First Person Shooter viewpoint. There are 4 parts in this game namely Prologue, Phase Before Islam, Islamic Phase, Epilogue. The test results show that all game features can work properly. Then the game was tested on 10 users and they stated that they had received adequate information about Khalid ibn al-Walid from this game.
Study of comparison of tail wind turbines in wind power plants
Authors: Yulianto Y , Mandayatma E , Priyadi B
Published: January 2020

The windmill tail that is widely used is a single tail that has a performance of a large zero offset. This study is to get a windmill tail pattern with a fast response and good direction stability. The aim of this study is to obtain a windmill tail pattern with the most stable direction stability under load conditions and changing wind direction by comparing the stability of several alternative windmill tail patterns. The process of data collection is done by comparing the performance of 3 types of windmills: single tail, semi-differential tail, and differential tail. The variables are speed of wind direction, speed of change of wind direction, differential angle of zero offset error, speed of change of direction, and torque produced. The material obtained from the test results was transcribed and analysed. The results of the analysis are used to design windmill tail prototypes. From the analysis results show that the swing torque at the differential windmill tail is proportional to the sinusoidal swing angle, the differential angle gives the effect of the torque scale in a cosine manner. Whereas on a single pinwheel produces torque proportional to the sine squared with respect to the swing angle. The differential tail has performance with better speed and stability, but produces vertical vibrations so it is preferable to use a semi-differential pinwheel with a differential angular size tuned in the system.
Detection of Salak Chips readiness on vacuum frying machines based on vacuum pipe temperature and frying time
Authors: Mustafa L D , Susilo S H , Perdana R H Y
Published: January 2020

Fruits are one of the horticultural commodities that have high economic value and have the opportunity to be exported. Fruit products in Indonesia are generally consumed in the condition of fresh fruit and very little processed into processed food. Because fruits are seasonal and perishable after being harvested, the selling price of the product has decreased significantly during the harvest season. One alternative to increase save time and fruit utilization is by processing fruits into chips. Fruit chips are a healthy snack because contains high fiber. Processing of fruit chips can be done using ordinary frying with dyeing on cooking oil at atmospheric pressure (deep frying) or with a frying pan at low pressure (vacuum frying). The purpose of this study is to examine the relationship between the temperature of the frying pan and the temperature of the flow of the pipe on the vacuum frying machine from the first time frying process until the chips are cooked. This research is limited to the following matters: the type of vacuum frying machine used is a water jet pump model 2 HP, a vacuum pressure 65 cmHg, the frying setting temperature is 90°C, and the main ingredient of salak chips with a capacity of 5 kg. The results of the salak chip frying experiment results are as follows: Whatever the temperature of the frying pan before dipping the oil chips, the water vapor suction channel will remain at 27°C, and after the chips have been oiled, the temperature changes slowly to the highest value (same as the frying temperature) and the longer it goes down until it reaches room temperature again (27°C) this is due to the water content depleted from the fruit chips that have run out and the fruit chips have been fried in about 90 minutes.
Glycerol from waste frying oil as sustainable fuel
Authors: Rubianto L , Santosa S , Sudarminto H P , Udjiana S S
Published: January 2020

In search of renewable and environmentally friendly fuel, transesterification of waste frying oil was an excellent method to produce biodiesel. Transesterification was not only producing biodiesel but also creating glycerol as by product. Unfortunately, transesterification of waste frying oil causes the colour of glycerol usually dark brown due to impurities, caramelization, and Millard reaction. In order to improve quality of glycerol, absorption using activated charcoal was applied. Glycerol was intended to replace diesel fuel for boiler burner. Due to high viscosity, glycerol was mixed with methanol. Mixture of glycerol and methanol in various compositions was applied on boiler burner. By analyzing the flame and flue gas, composition of 10% glycerol and 90% methanol was the best mixture.
Drivers of logistics service innovation in Third Party Logistics business
Authors: Sumantri Y
Published: January 2020

The desire to focus on the company’s core business processes has impacted companies to outsource their logistics activities to Third Party Logistics (TPL). These conditions create the demand for logistics services so that the TPL business grows significantly. Service innovation from TPL holds a critical role in the development of logistics business clusters because TPL is a new growth source from the regional and national economy. What factors drive TPL business to innovate has not been much studied in the logistics research literature. Few studies have addressed drivers of logistics service innovation. Deficiency of empirical research on the drivers of logistics service innovation in TPL business, so that this paper study empirical studies on the factors that influence innovation in TPL business. This study aims to identify the factors that drive innovative logistics services from TPL business so that they can provide the basis for developing innovation in TPL. Content analysis of extant literature was conducted. This study found that a lot of knowledge about innovation drivers in TPL was identified in theoretical based, but many of these components were not implemented yet. This study shows that TPL will achieve successful operational performance if innovation is executed with suitable knowledge management so the TPL can achieve effective communication networks.
Performance analysis of Proxmox VE firewall for network security in cloud computing server implementation
Authors: Ariyanto Y , Harijanto B , Firdaus V A H , Arief S N
Published: January 2020

Virtualization server uses the hypervisor technology in its implementation. Hypervisor is one of the virtualization techniques. Where this technique runs several operating systems together in one host. Cloud computing is a combination of the use of internet-based computer technology. The Open source Proxmox VE (Virtual Environment) is a virtual machine operating system. Where virtual machines are built from the Debian Linux operating system, with the modified RHEL kernel. A firewall is a system designed to prevent attacks on the network. Firewalls can be software or hardware that filters network traffic. Proxmox VE Firewall provides a way to protect network infrastructure. In Proxmox VE firewall allows setting rules for all hosts in a cluster or for virtual machines. In this study, the performance of the firewall from the server virtualization using ProxmoxVE will be examined. This study is intended to determine the performance of the firewall default from Proxmox VE. Firewall testing is done by creating filtering rules in the Proxmox VE cloud server. The results of this study will provide an analysis of the performance of the Proxmox VE firewall that runs on cloud servers. The analysis presents that iptables firewall rules can be applied to cloud servers.
SIBI (Sistem Isyarat Bahasa Indonesia) translation using Convolutional Neural Network (CNN)
Authors: Syulistyo A R , Hormansyah D S , Saputra P Y
Published: January 2020

Deaf people are one of those with disabilities who cannot speak and hear. Deaf people using sign language for communication who use sign language with hand gestures, body and convey facial expressions using sign language. One important component in sign language is the alphabetical finger or the manual alphabet needed to complete communication. The alphabet of the finger is done by spelling words on spoken language, by spelling letter by letter using a finger. This method is used to spell the name or mention the word. However, not everyone understands sign language, so tools needed to bridge communication between people who are deaf with normal people. One solution that will be offered is to use computer technology as a tool to recognize sign language. The technology is an automatic language translator system that process input images using by using the Convolutional Neural Network (CNN). On this research consist of 3 class such us A, assalamualaikum and hallo which get the accuracy respectively 100% for each class.
The effect of information quality, system quality, service quality on intention to use and user satisfaction, and their effect on net benefits primary care application at primary health facilities in Malang
Authors: Ariyanto R , Rohadi E , Lestari V A
Published: January 2020

The Indonesian government has serious attention to facilitate the health of its people, one of which is by establishing Badan Penyelenggara Jaminan Sosial (BPJS) hereinafter BPJS. The Government of Indonesia collaborates with several parties including primary health facilities, General and Regional Hospitals, as well as general practitioners and specialists who have been appointed by BPJS. The aim of this study is the user’s perception of Primary Care applications at primary health facilities BPJS in Malang. This study uses the DeLone & McLean (D&M) Update IS Success Model to assess the success of an information system where its use is mandatory at primary health facilities. The model contains 6 dimensions that can measure the success of a system, i.e. Information Quality, System Quality, Service Quality, Use, User Satisfaction and Net Benefits. This research is a quantitative study using a questionnaire with a Likert scale. Purposive sampling is a method used in sampling. The respondents consist of doctors or admins who operate primary care applications at primary health facilities. The results of this study indicate that primary care applications can be categorized as successful information systems for each dimension of success in the D&M Update IS Success Model.