bluuebunny/crossref_metadata_2025 huggingface dataset:
IMPROVING HISTORICAL LITERACY THROUGH SHORT STORY WRITING WITH THE HELP OF ARTIFICIAL INTELLIGENCE
Authors: Hartati Yayu , Hendrawan Jajang Hendar Hendrawan
Published: December 2024

This research explores the potential of Artificial Intelligence (AI) in enhancing historical short story writing to improve students' literacy and creativity. A qualitative research method with a case study approach was used, collecting data through interviews, observations, and document analysis. The findings indicate that AI is highly beneficial in writing historical short stories by providing quick access to historical facts, assisting in plot and character development, and improving the quality of writing through grammar and style checks. AI also supports students' creativity by offering fresh ideas and overcoming creative blocks. However, challenges like unequal access to technology and over-reliance on AI still exist. The research concludes that while AI can enrich the learning experience by making history education more engaging and interactive, human guidance remains essential for the optimal development of students.
 
Keywords: Historical Literacy, Short Stories, Artificial Intelligence.
DIGITAL MARKETING TO BUILD THE ENTEPRENEURIAL SPIRIT OF TRADITIONAL CULINARY
Authors: Wantini Widaningsih Erni , Syobar Khaerul
Published: December 2024

The study focuses on Kampung Adat Cireundeu, a community considered a stronghold of Sunda culture in West Java. It examines the role of digital marketing in fostering entrepreneurship, especially among teenagers. This research gathers and analyzes various relevant sources to understand how digital marketing can help the growth of entrepreneurship in Indigenous villages that maintain the Sunda Wiwitan tradition. This is done using literary study methods and ethnographic approaches. Research results show that digital marketing effectively promotes traditional culinary services, such as cannabis treatments. It also gives local entrepreneurs the tools and platforms to adapt and quickly change the market. Digital marketing helps reach a wider audience at a low cost and analyzes data in real-time to support better decision-making.
THE VALUE AND TECHNOLOGY: MAINTAINING BALANCE IN SOCIAL SCIENCE EDUCATION IN THE ERA OF ARTIFICIAL INTELLIGENCE
Authors: Nurhayati Tita Nurhayati , Halimah Lili
Published: December 2024

In the era of Industrial Revolution 4.0, technology, especially artificial intelligence (AI), has brought major changes to various aspects of life, including education. Social science education now faces challenges in maintaining moral and ethical values ​​amidst the rapid adoption of technology. This research aims to explore how values ​​and technology can go hand in hand in social science education in the AI ​​era. Using a qualitative approach and literature analysis, this research finds that AI has the potential to enrich social science learning through personalized learning and in-depth data analysis. However, the integration of these technologies also poses risks, such as algorithm bias and reduced human interaction. Therefore, it is important to maintain a balance between the application of technology and the cultivation of human values, with strategies that prioritize the development of critical and ethical thinking skills. It is hoped that this research can provide guidance for educators in integrating AI into the social science curriculum without ignoring essential humanist aspects.
Keywords: Values, Technology, Balance, Social Science Education, Era of Artificial Intelligence
THE ARTIFICIAL INTELLIGENCE, SOCIAL SCIENCES LEARNING INNOVATION CATALYST
Authors: Susyanah Susan , Fajar Arnie
Published: December 2024

Digital technology and artificial intelligence (AI) development has opened up new educational opportunities, including social education studies. In this digital era, improving learning quality is becoming increasingly urgent. Social education studies, which aim to shape students' understanding of society, geography, and citizenship skills, face various challenges, ranging from a lack of student engagement to limited resources. AI technology offers innovative solutions through personalized learning, quick feedback, and a dynamic learning environment. AI-based learning supports lifelong education, providing easy access to online resources for all age groups. This research aims to analyze the potential of AI in social education studies by identifying relevant AI applications, evaluating the impact of AI implementation, and developing AI-based learning models. In addition, the study identifies challenges, formulates strategies to overcome them, and formulates policy recommendations for educators and technology developers. The method used is qualitative analysis through a literature review from journals, books, and related articles in the last ten years. The study results show that AI has great potential to improve the quality of social learning studies by providing programs tailored to student needs, analyzing learning history, and developing better learning materials. Examples of AI applications in education include ChatGPT for natural language processing, AI-based learning systems, virtual assistants, and educational data analysis. With wise application, AI can improve student engagement, material comprehension, and analytical skills and prepare them for a connected and adaptive future to changing times.
Keywords: Artificial Intelligence, Social Sciences Education, Learning Innovation.
SOCIODRAMA LEARNING MODEL IN SOCIAL STUDIES FOR JUNIOR HIGH SCHOOL AS AN EFFORT TO ENHANCE STUDENT CREATIVITY
Authors: Shelsha Pertiyanasari Bellinda , Sunarti
Published: December 2024

This research aims to find out how the sociodrama learning model is applied in junior high school social studies as an effort to increase student creativity. This research uses a descriptive method - analysis with a qualitative approach and uses literature review as a source. There are 4 results and discussions in this research, namely (1) social studies learning, (2) increasing junior high school students' creativity in learning, (3) Application of the Sociodrama Learning Model (4) Efforts made by teachers in implementing the Sociodrama Learning Model to Increase Student Creativity. With this, it can be concluded that in junior high school social studies is a lesson with a lot of material, therefore, so that learning can attract students' interest, teachers must apply a variety of learning models, for example the sociodrama learning model in this lesson, students automatically participate actively in the class. because this sociodrama learning model is more pressing, that students are asked to act in class and understand the role of characters so that learning feels more fun, interesting and can increase students' creativity in learning activities.
 Keywords: Learning Model, Sociodrama, creativity.
KAMPUNG MAHMUD, A PORTRAIT OF SOCIAL, CULTURAL, AND TECHNOLOGICAL TRANSFORMATION
Authors: Halimah Lili Halimah , Fajar Arnie , Heryani Heni
Published: December 2024

Identity, lifestyle, and overall societal structure are often influenced by socio-cultural transformations. Kampung Mahmud has undergone socio-cultural transformation marked by the influx of technology and the onset of globalization, leading to social, cultural, and local lifestyle changes. The aim of this research is to depict the social and cultural changes in Kampung Mahmud and the impact of technology introduction on the local community. This study employs a qualitative approach involving interviews and documentation. The research aims to determine the questions to be investigated, and how socio-cultural transformations occur in Kampung Mahmud, including the role of traditional elders in managing these changes. The findings indicate that the community of Kampung Mahmud has experienced socio-cultural and technological transformations influenced by technology, politics, and cultural interactions. The village elders lack authority to prohibit or prevent these changes; instead, it is the responsibility of the villagers to adhere to or reject the rules established by their ancestors. These results contribute to the literature on socio-cultural transformation in traditional societies and provide recommendations for stakeholders to incorporate them into school curricula.
THE DEVELOPMENT OF WORDWALL WEB-BASED EDUCATIONAL GAMES TO INCREASE LEARNING ACTIVENESS GRADE IV STUDENTS UPT SDN 2 KETANON KEDUNGWARU
Authors: Yudi Setiawan Reta , Prayogo Bangkit
Published: December 2024

Science learning is a subject that not only provides an understanding of the real form of rules or concepts regarding the environment that requires various kinds of problem solving but is always required to improve achievement in mastering it. Activeness in the world of education is required in order to achieve complex reciprocal relationships. The purpose of developing an educational game based on Web Wordwall is to increase the learning activity of class IV UPT SD Negeri 2 Ketanon Regency. The method used in this research is research and development (r&d). In this development the researcher uses the ADDIE model which consists of 5 steps namely analysis, design, develop, implementation and evaluation. The results of the percentage of material experts on learning media in the form of wordwall web educational games with a total percentage of 100% and declared "very valid" and media experts' assessment of learning media in the form of wordwall web educational games with a total percentage of 95% and declared "very valid". Based on the user's attractiveness response to the questionnaire, the teacher obtained a score of 100 and the response increased student activity with a score of 90% which was included in the "very valid" category and the results of the N-gain test for the results of increasing student activeness obtained from 47.5 to 90 which shows there is an increase in the high category.
 
Keywords: educational games, wordwall web, activeness
USE OF INTRANET FOR CBT-BASED ASSESSMENT (COMPUTER BASED TEST) AT SENIOR HIGH SCHOOL
Authors: Yanti  , Siswandi
Published: December 2024

Advances in information and communication technology have had a major impact on various aspects of life, including the education sector. One important innovation in this field is the implementation of Computer-Based Test (CBT) for assessment. The CBT system offers a number of advantages, such as time efficiency, increased assessment accuracy, and ease of data management. On the other hand, the implementation of CBT requires a strong infrastructure, one of which is an intranet network. This study aims to understand how intranets can be optimized in the implementation of CBT assessments, identify the benefits and challenges that arise, and provide recommendations for better implementation. This research method uses existing and trusted literature or references to be analyzed and the results are used to solve the problems being studied. Zed in Kartiningsih's research (2015) said that the literature study method is a series of activities related to the method of collecting library data, reading and recording, and managing materials. The data for this study were collected through direct observation of the implementation process of CBT-based assessments at SMA Negeri 6 Pontianak. Next, to complement the observations and interviews, the researcher did was to record and view documents to analyze the implementation process of CBT-based assessments. The results of the study indicate that the use of intranet in CBT assessment can improve operational efficiency, strengthen data security, and provide flexibility in accessibility. However, challenges such as the need for adequate infrastructure and competent technical expertise still need to be addressed. Recommendations from this study are expected to contribute to educational institutions in optimizing the use of intranet for CBT assessment and provide direction for further research in the future.
Watching Like a Kid: Connections between Kidults and Children’s Media
Authors: Rowe Rebecca
Published: December 2024

There is currently tension concerning American adults’ relationship to children’s media. While many adults are deeply invested in children’s media, many Americans have a very real disdain for such adults. This article theorizes how children’s media work to navigate this tension by reimagining the connections between such media and American adults. I argue that the kidult became relatively mainstream because children are being treated more like adults and because adults today often do not adhere to an adulthood defined by an economic situation that no longer exists, leading to adults who exist between the two spaces. These kidults have not lived the childhoods or adulthoods sold to them by various kinds of media, so they reimagine what it means to exist between the two non-existent images, bringing their childhood desires into their adulthoods. Children’s media then encourage people to continue engaging with media from their childhoods long into their adulthoods, marketing to and benefitting from this new figure of adults with childlike tastes. I argue that American kidulthood can only be understood through its relationship to children’s media as both media audience configurations and cultural constructions of age shift toward blurred boundaries between childhood and adulthood.
“It’s Amazing What a Girl Can Do” Neoliberal Girlhood, Disability, and Charity in Our Generation Dolls
Authors: Goldak Elena
Published: December 2024

Robin Bernstein uses the phrase “scriptive things” to describe material artifacts that, if read using archival knowledge and historical context, offer insights into the actions of humans who interact with the object and the ways that those actions may be prompted or scripted. By reading the toys, visual designs, and texts of Our Generation (OG) dolls as “scriptive things” (to follow Bernstein), she aims to investigate what kind of imagined reality OG invites us into when we play with their dolls. In particular, the author is interested in the heavy-handed and often contradictory politics of class, race, cisness, and disability entangled within OG’s imaginings of girlhood. In this article, she shows how OG engages a discursive production of a neoliberal girlhood formulated by middle-class whiteness, cisfemmeness, and ableism, discussing how this neoliberal girlhood governs representations of disability and emerges through the language of charity. This analysis offers insight into the discursive relationships formed between girlhood, disability, and charity under neoliberalism.
Oplan Tokhang and Stories of Childhood: Children across Literature and (Trans)Media Places during the Duterte Regime in the Philippines
Authors: Sayuno Cheeno Marlo M.
Published: December 2024

In the Philippines, children are one of the most vulnerable sectors disadvantaged by the past administration headed by former president Rodrigo Duterte. The Human Rights Watch reports that dozens of children have become victims of Oplan Tokhang, the president’s flagship program on the war against drugs since he claimed office in 2016 ( oplan is a slang for “plan” and tokhang is a play on Filipino words toktok or “knock” and hangyo or “plead”). This article seeks to explore the case of Filipino children and how they operate within literary, media, and socio-political dimensions. Selected works published during the Duterte regime, particularly those that tackle socio-political narratives, are presented. Afterward, the media representations of children in the news and on social media are discussed. The literary and media spaces provided for the concept of childhood are linked through Henry Jenkins’s concept of transmediality. By presenting storyworlds where children are at the center of navigation across narrative/nonnarrative media/nonmedia spaces, the meanings of childhood in the Philippines are unearthed from the transmedia place that these spaces create for the Filipino child.
Las esteras. Tejiendo la memoria de la ciudad popular
Authors: Ramírez Corzo Daniel , Vera Cubas Javier
Published: December 2024

Este artículo explora el papel de las esteras en la historia y la memoria de las barriadas de Lima, Perú. Analiza cómo este material, fundamental en la ocupación y construcción inicial de las viviendas ha evolucionado, examinando su trayectoria en el arte, la arquitectura y el imaginario colectivo, destacando su potencial como parte del patrimonio urbano popular. La investigación incluye proyectos experimentales para recontextualizar las esteras en el espacio público. Los autores proponen que las esteras pueden servir como catalizador para la memoria social y la identidad en las barriadas consolidadas, trascendiendo su uso original para convertirse en un elemento significativo en la producción de espacio público popular y en la construcción de una memoria urbana más justa.
Religiöse Transformationen im Spiegel der materiellen Überlieferung des ‚langen‘ 15. Jahrhunderts
Authors: Gluchowski Carolin
Published: December 2024

The Easter prayerbook Ms GKS 3452-8° in the Royal Danish Library, Copenhagen, marks the beginning of a 150-year tradition of Latin and Low German manuscript production at the Cistercian convent of Medingen, reflecting the nuns' ‘long’ 15th century. This period, documented by the 65 manuscripts in the Medingen corpus, lasts more than a century, from the early 1400s to the 1550s/1570s. Completed in 1408 by Cecilia de Monte, the Copenhagen Easter prayerbook offers a rare glimpse into the origins of this remarkable tradition around 1400. This article suggests that the manuscript may have served as a model for subsequent works and calls for further research on this group of manuscripts to explore continuities and changes in Medingen manuscript production throughout the "long" 15th century. This enterprise will greatly enhance the understanding of Pre-Reformation religious writing by women and shed light on the devotional culture of the early 15th century.
[REVIEW]: Krzysztof Bracha, Maria Mediatrix – Maria Adiutrix. Pobożność maryjna w nauczaniu kaznodziejskim w Polsce późnego średniowiecza. Sermones dominic ales et festivales z tzw. kolekcji Piotra z Miłosławia, Wydawnictwo DiG, Warszawa 2023, pp. 328.
Authors: Kaczor Ewelina
Published: December 2024

Review of Krzysztof Bracha's monograph: Maria Mediatrix – Maria Adiutrix. Marian Devotions in the Teachings of Late Medieval Preaching in Poland. The Sermones dominicales et festivals from the So-called Collectione of Piotr of Miłosław, Warszawa 2023
Review of Rafał's Kubicki monography
Authors: Biskup Radosław
Published: December 2024

The latest monograph by Rafał Kubicki, a medievalist from Gdańsk, is devoted - generally speaking - to rural areas in the state of the Teutonic Order. In this synthetic approach, the author draws on a rich tradition of research into the development of settlements, rural society, production relations and the organisation of agriculture, breeding and cultivation etc. in the territory in question. It is worth adding that this is not his first research expedition to the Prussian countryside under rule of Teutonic Order: in 2012 his habilitation on milling in the Teutonic Order's state from the 13th to the mid-15th century was published. Similar topics are also taken up by Rafał Kubicki's students: in 2022, at the University of Gdańsk, a dissertation was defended entitled "Komturstwo Tucholskie (1330-1454). Space-economy-society', written by Grzegorz Woliński. [...]
Construimos una escuela que previene el acoso entre estudiantes. Guía para docentes
Authors: Claro Espejo Natalia
Published: December 2024

La “Caja de herramientas para una ciudadanía democrática” es una propuesta pedagógica que comprende materiales educativos para estudiantes, docentes y directivos de escuelas secundarias. Busca contribuir a la formación de una ciudadanía activa, comprometida con valores y principios democráticos, así como al desarrollo personal de las y los adolescentes a través de iniciativas creativas que faciliten la organización de proyectos en beneficio de sus comunidades.
Esta herramienta se sitúa en el área de Desarrollo Personal, Ciudadanía y Cívica (DPCC) del Currículo Nacional de la Educación Básica (CNEB) del Perú. Asimismo, involucra a las áreas de Comunicación y Arte y Cultura. Este material se ha implementado en diversas instituciones educativas públicas, en alianza con el Jurado Nacional de Elecciones (JNE) y Fe y Alegría del Perú.
Sus objetivos están enfocados en que las y los estudiantes:
• Fortalezcan su ciudadanía activa, promoviendo su participación en la vida pública y su compromiso con los valores democráticos.
• Desarrollen sus competencias para abordar los desafíos sociales y políticos de su entorno, que aporten en la construcción de una sociedad democrática, institucional y participativa.
• Construyan una identidad personal que les permita reconocer sus intereses, valores y capacidades, y actuar de acuerdo con ellos.
Optimizing Arowana Fish Breeding with IoT Aquaculture
Authors: Agus  , Suryadiputra Liawatimena  , Gilang Wiranda  , Diki Arisandi
Published: December 2024

Monitoring and controlling water temperature and pH levels are crucial aspects in maintaining a healthy environment for breeding Arowana fish. Arowana fish are sensitive to fluctuations in water temperature and pH levels, which can lead to stress, diseases, and even death. Therefore, it is essential to regularly monitor and maintain the temperature and pH levels within suitable ranges for the fish. This study aims to develop Internet of Things (IoT) technology that is expected to assist Arowana fish farmers in monitoring and controlling more effectively and practically. The methodology employed in this study is a case study approach, with Arowana fish farmers as respondents. In monitoring the water quality for Arowana fish, many farmers still rely on traditional farming models that heavily depend on experience, lacking the ability to assess water quality and environmental changes scientifically. By utilizing LoRa and cellular technologies, this study provides intelligent solutions for water quality monitoring to create controlled and sustainable growth conditions. The ultimate outcome of this research is the development of an IoT-based application designed to enhance the efficiency of Arowana fish farming. This application involves automatic control of water pH and temperature in three different treatments. The methodology employed in the application design involves the development of an IoT-based system integrated with temperature and pH sensors. The functionality of the application includes real-time monitoring and automatic control of the aquarium environment. Testing was conducted through a series of field trials to ensure system performance and reliability. With a pH range of 6.5 - 7.5 and temperature range of 26 - 30°C, this application has proven to provide optimal responses for Arowana fish farming, enhancing growth and reducing feeding time.
Recommendation System to Determine Achievement Students Using Naïve Bayes and Simple Additive Weighting (SAW) Methods
Authors: Jazaudhi’fi Ahmad , Vitianingsih Anik Vega , Kristyawan Yudi , Lidya Maukar Anastasia , Yasin Verdi
Published: December 2024

Giving appreciation to outstanding students can motivate students to compete with each other in learning. MA Tanwirul Qulub Tanggungan often experiences difficulties in determining outstanding students due to There is no application that can assist school management in identifying outstanding students, the implementation is considered less than optimal. besides that, the determination of outstanding students is still based on report cards that are only ranked, and there are no criteria that refer to the K-13 curriculum. The purpose of this research is to offer a solution to create a recommendation system for selecting outstanding students using the parameters of midterm exams, final exams, assignments, attendance, attitude, extracurricular activities, organizations, and award certificates using decision support system techniques. Extracurricular grades are taken from Scouting activities only because students are generally required to participate in them. Naïve Bayes and Simple Additive Weighting methods are used in this research, where the Naïve Bayes method classifies the categories of outstanding students and not, while the SAW method is used for ranking.  The contribution of this research has the potential to increase school efficiency in student assessment and support efforts to improve the quality of education by rewarding students appropriately. The validation test results of Naïve Bayes and SAW techniques get an accuracy value of 100%, which shows that the SAW method can produce the best alternative recommendations
Effect of forced swimming on the performance of the "water escape test"
Authors: Tur M. A. , Belozertseva I. V.
Published: December 2024

Housing conditions and prior life experiences can influence, to varying degrees, animal behavior, brain regions that regulate important neural and physiological functions such as memory, stress responses, and emotional behavior. Stressors of low to moderate intensity, occurring in enriched environments and training, promote the development and maintenance of cognitive functions, whereas exposures of excessive severity and/or duration lead to maladaptation and distress, with negative effects on animal nervous system functioning in general and cognitive functions in particular. Based on these facts, external physical effects of “excessive intensity” can be used for the formation and study of various cognitive disorders. Accordingly, it was hypothesized that a similar but unavoidable exposure to the aversive conditions of the aquatic environment of the “forced swim” would affect the cognitive ability of animals in the “water escape” test. For the first time the effect of forced swimming stress (15 min) on the ability to solve the task of the “water escape” test and the development of the diving skill was evaluated. It was shown that the experience of forced swimming on the eve of the test has a “dramatic” effect on the ability to solve the task of diving, and the negative effects persist even after 2 weeks.
The use of the forced swim procedure before performing the “water escape” test looks like a promising way to model stress-induced cognitive dysfunctions. The persistence of the effect of forced swimming on the “water escape” test task completion (at least 14 days) opens the prospect for evaluating the effects of subchronic administration of pharmacological agents with antidepressant and procognitive properties.
The role of the serotoninergic system in functional recovery after spinal cord injury
Authors: Konovalova S. P. , Sysoev Y. I. , Vetlugina A. , Arsentiev K. A. , Musienko P. E.
Published: December 2024

The serotoninergic system plays an essential role in the modulation of the spinal networks activity involved in the control of motor, sensory, and visceral functions. Spinal cord injury (SCI) can induce a state of overexcitation that contributes to pain, spasticity, and dysregulation of autonomic functions. At the same time, 5-NT axons are known to adapt faster than others to pathophysiologic changes and leave the ability to sprout and regenerate after injury. A number of experimental animal studies as well as some clinical observations suggest that the serotoninergic system is a key endogenous resource for posttraumatic recovery after SCI. Specific therapy may include administration of serotoninergic drugs and intraspinal transplantation of 5-NT neurons. This review discusses the role of the serotoninergic system in functional recovery after SCI and the prospects for the use of serotoninergic drugs in neurorehabilitation.
Projection neurons of the prefrontal cortex, their participation in the formation of various forms of behavior and expression in them of brain-derived neurotrophic factor
Authors: Drozd U. S. , Frik Y. A. , Smagin A. V. , Lanshakov D. A.
Published: December 2024

The prefrontal cortex (PFC) plays a key role in cognitive plasticity and is involved in various processes of higher nervous activity. At the same time, studying the processes underlying various forms of behavior in which PFC neurons participate is a non-trivial task. The associative functions of the PFC are associated with the nature of the connectivity of this structure with other areas of the brain, which, according to recent data, is much more complex than previously thought. Thus, it becomes clear that the axons of PFC projection neurons have many collaterals projecting to many different targets in the brain. In this review, we highlight the latest results in studying the connectivity of PFC neurons using the latest methods for analyzing projections and single-cell transcriptomes. Brain-derived neurotrophic factor (BDNF) plays an important role in the functioning of these neurons and their projection targets, but the transport of this neurotrophin by PFC projection neurons to structures where it is not locally expressed may be especially important. We review recent results mapping such neurons in the PFC, highlighting Bdnf expression and potential role in the pathogenesis of mental disorders.
Expression of apoptosis, autophagy and necroptosis effectors in cells of rat hippocampus after excessive F- consumption
Authors: Nadei O. V. , Agalakova N. I.
Published: December 2024

The work examined the expression of apoptosis, autophagy and necroptosis markers in hippocampal cells of rats after long-term consumption of excessive F- doses at the transcriptional and translational levels. Male Wistar rats were divided into 4 groups receiving 0.4 (control), 5, 20 and 50 mg/l F- (as NaF) for 12 months. The changes in contents of effectors of mitochondrial (Bcl-2, Bax, Caspase-9, Caspase-3) and receptor (Caspase-8, Fas) pathways of apoptosis, mediators (Ulk-1, Beclin-1) and modulators (AMPK, Ark, mTOR) of autophagy, as well as that of necroptosis (RIP and MLKL) were assessed by immunoblotting, the gene expression (Bcl2, Bax, Casp3, Ulk1, Beclin1, Prkaa1, Akt, and mTor) – by real-time PCR. In the hippocampus of F – exposed animals, the expression ratio of Bcl2/Bax genes and Bcl-2/Bax proteins decreased, caspase-9 and caspase-3 were activated, but the level of caspase-8 and membrane Fas receptor remained stable. Long-term F- consumption had no effect on the content of autophagy initiator Ulk-1 and protein kinases AMPK, Akt and mTOR, but resulted in inhibition of key autophagy mediator Beclin-1. The expression level of necroptosis RIP and MLKL effectors in the hippocampal cells of rats received excessive F- did not change as well. Thus, long-term F- exposure was accompanied by activation of apoptosis, mainly through the mitochondrial pathway, at the background of autophagy suppression.
Participation of Ca2+-acceptor proteins in the mechanisms of the exo-endocytic cycle of synaptic vesicles in the motor nerve endings of the somatic musculature of the earthworm Lumbricus terrestris
Authors: Nurullin L. F. , Almazov N. D. , Volkov E. M.
Published: December 2024

Using fluorescence microscopy, we studied the participation of Ca2+-acceptor proteins in the processes of the exo-endocytotic cycle of neurotransmitter quantal secretion in the neuromuscular junction of the somatic muscle of the earthworm Lumbricus terrestris. Inhibition of calcineurin, calmodulin and Ca2+/calmodulin dependent protein kinases led to an increase in the process of endocytosis. Blocking the phosphorylation of synaptic proteins enhances the process of endocytosis, causes an increase in the size of the total vesicular pool and accelerates the turnover of synaptic vesicles. It can be concluded that calcium modulation of vesicle exo-endocytosis at the synapses of the evolutionarily primary somatic muscles of annelids occurs with the participation of calcineurin, calmodulin and Ca2+/calmodulin-dependent protein kinases.
Participation of adrenoreceptors in the mechanisms of pathologic cardiac rhythm induced in newborn rats by nickel chloride administration
Authors: Kuznetsov S. V. , Kuznetsova N. N.
Published: December 2024

In experiments on 3-day-old rats to identify the possible involvement of adrenoreceptors (AR) in the development of pathologic heart rhythm with high-amplitude ( 0.5 c) bradycardic complexes (PHRBC) occurring in newborn rats after NiCl2 administration, a comparative analysis of changes in heart rate variability (HRV), heart rate, and respiration after injection of nickel chloride and a high dose of the β-AR agonist isoproterenol was carried out. Injection of NiCl2, which blocks T-type voltage-dependent Ca2+ channels (T-VDCC), causes in 100% of rats the occurrence of PHRBC accompanied by a decrease in the role of neural influences and an increase in the role of neurohumoral factors in the mechanisms of heart rate regulation. Activation of β-AR causes shifts of physiological parameters qualitatively and quantitatively similar to those observed after NiCl2 poisoning in rats, but PHRBC does not occur. Pharmacological analysis with premedication of rats with β-AR antagonists (propranolol, atenolol) or α-AR antagonists (phentolamine) followed by NiCl2 administration showed that β-AR blockade with the nonselective adrenolytic propranolol prevents the development of PSRBC in half of the rats. In animals with pathologic arrhythmia occurring after NiCl2 injection, a rapid increase in the load on the sympathoadrenal system is noted, and the initial (background) instability of the mechanisms of heart rhythm regulation is revealed. Blockade of α- and β1-AR does not prevent the development of PHRBC during subsequent NiCl2 administration, which suggests the participation of β2-AR in the development of arrhythmia. Administration of the selective β2-AR agonist clenbuterol to rats leads to a decrease in HRV, including neurohumoral regulation and the appearance of low-amplitude ( 0.1 c) bradycardic complexes (BC) in 22% of rats. The results obtained by us together with the analysis of the literature suggest that β-AR plays an important role in the complex changes in the balance of regulatory influences in the occurrence of PHRBCs. Activation of β1-AR contributes to increased release of catecholamines by adrenal chromaffin cells, increased role of neurohumoral component of heart rhythm regulation and causes activation of β2-AR. Blockade of β2-AR, on the contrary, reduces the release of catecholamines and prevents the development of pathological arrhythmia. The second necessary factor leading to the development of arrhythmias with high-amplitude BCs is blockade of T-type calcium channels.
Ocean floor structure in the junction area of the King Trough and the Azores-Biscay Rise (North Atlantic)
Authors: Skolotnev S. G. , Peyve A. A. , Dobrolyubova K. O. , Ivanenko A. N. , Patina I. S. , Bogolyubskiy V. A. , Dobrolyubov V. N. , Veklich I. A. , Dokashenko S. A. , Lyubinetskiy V. L. , Ilyin I. A.
Published: December 2024

The paper, based on geological and geophysical data obtained during 55-th expedition of the research vessel “Akademik Nikolaj Strakhov”, examines the structure of the King’s Trough and its immediate surroundings (King’s mesostructural cluster), located on the eastern flank of the Mid-Atlantic Ridge in the North Atlantic. Six provinces were identified within the southeastern part of the King’s Trough, based on the results of bathymetric mapping, each of which has its own morphostructural appearance, which was formed as a result of multistage tectonic and volcanic processes, alternating and conjugate with each other in time. According to seismoacoustic profiling data, three main types of seismic faces have been identified: a) pelagic complexes; b) deposits of turbidite flows; c) chaotic facies of gravitational genesis. It is shown that the anomalous magnetic field of the study area is a superposition of linear and isometric anomalies. The first were formed during the generation of oceanic crust in the axial spreading zone. The second are associated with volcanic massifs formed in intraplate conditions. The obtained data confirm the assumption that the formation of the King’s Trough was preceded by the formation of an extended arched uplift, which became the scene of intense intraplate volcanism, the intensity of which increased from the southeast to the northwest. This stage was followed by subsidence of the axial part of the uplift with the formation of the King’s Trough and the Peak and Freen Troughs.
New data on isotopic U-Pb age (LA-ICP-MS method) of zircon from intrusive rocks of the Kuru-Tegerek gold-copper-molybdenum skarn deposit (Middle Tien Shan, Kyrgyzstan)
Authors: Soloviev S. G. , Kryazhev S. G. , Semenova D. V. , Kalinin Y. A. , Bortnikov N. S.
Published: December 2024

The paper presents new isotopic U–Pb data (LA-ICP-MS) method of zircon from the main types of intrusive rocks at the Kuru-Tegerek gold-copper-molybdenum skarn deposit situated in the Chatkal segment of the Middle Tien Shan. This and other gold, copper, tungsten and molybdenum deposits are parts of the extended Late Paleozoic metallogenic belt of Tien Shan. The concordant isotopic U–Pb values obtained for zircon autocrysts from the rocks of sequential intrusive phases span over the interval from approximately 323 to 311 Ma. This interval comprises the crystallization of gabbro-diorite (from 323.5±2.5 Ma to 323.2±6.8 Ma) and tonalite (from 321.4±3.8 Ma to 311±3.8 Ma). The age dates obtained for these zircon autocrysts correspond to the emplacement of these moderate-potassic intrusions in the Late Carboniferous and are almost coincident with the isotopic dates previously known for the high-potassic intrusions of the porphyry Cu–Au–Mo deposits of the Almalyk mineralized cluster (Kurama segment of the Middle Tien Shan), which were also emplaced in the Late Carboniferous (about 330–310 Ma). This corresponds to the subduction tectonic regime occurred in this region in relation to the steep-dipping (in the Kurama segment) or flat (in the Chatkal segment) subduction of a tectonic plate toward the north, under the structures of the Kazakhstan-Northern Tien Shan continental massif and accreted segments of the Middle Tien Shan. The intrusive rocks studied at the Kuru-Tegerek deposit contain also zircon xenocrysts (including these in the core of complex crystals) with the isotopic U–Pb age of some 1.9–2.1 Gb. These dates are in agreement with the age of metamorphic rocks in the Tarim craton basement and indicate the presence of the ancient continental crust in this segment of the Middle Tien Shan.
Composition and thermochronology of alkaline granites of Ingur massif: to problem of detection of factors contributing to formation of rare-metal mineralization in alkaline granites of Western Transbaikalia
Authors: Lykhin D. A. , Yarmolyuk V. V. , Vorontsov A. A. , Magazina L. O.
Published: December 2024

The article considers the question of what factors contributed to the formation of rare metal mineralization in alkaline granites of Western Transbaikalia. It is based on the results of comparison of petro-geochemical characteristics of alkaline granitoids of nearby ore-bearing Ingur and ore-free Sherbakhtinsky massifs. The rocks of these massifs form a common series of compositions with variations from syenites to alkaline granites (in the Sherbakhtinsky massif) and from alkaline granites to pegmatites (in the Ingur massif). The formation of this series of rocks is associated with a deep differentiation of the original magma common to both massifs, accompanied by a sequential decrease in magnesiality and the accumulation of rare elements (Be, Ta, Nb, Th, U, HREE) in residual melts. They reach the highest values in the pegmatites of the Ingur massif, in which rare metal mineralization appears. Its formation is associated with the fact that, according to thermochronological studies, the Ingur massif for 6 million years was located in the temperature range from 900° to 500°. Such a long stay in the region of high temperatures was accompanied not only by deep differentiation of residual melts, but also stimulated fluid activity, which contributed to the redistribution and accumulation of ore elements in pegmatites.
Permafrost boundary change in the Bolshezemelskaya tundra under different scenarios of climate change in the XXI century
Authors: Alexandrov G. A. , Ginzburg A. S. , Gytarsky M. L. , Chernokulsky A. V. , Semenov V. A.
Published: December 2024

Prognostic estimates of changes in the climatological boundary of the permafrost zone as a function of the average annual air temperature on the territory of the Bolshezemelskaya tundra under various scenarios of the development of the world economy until the middle of the XXI century have been obtained. It is shown that the shift of the climatological boundary of permafrost, determined by the threshold value of the average annual air temperature, in the north-eastern direction observed in the period from 1950 to 2010, according to the adjusted scenario forecasts, obtained using a climate model, will continue in the coming decades under any scenario of the development of the world economy and is an inevitable consequence of anthropogenic influence on the climate. The results of the study are important for assessing the prospects and development of a network of long-term observations, which is being created to monitor the state of permafrost and greenhouse gas fluxes in the Russian Federation.
Meta-sandstones of the Vilenga Suite in the Vetreny Belt: composition, isotopic-geochronological characteristics and sources of erosion
Authors: Mezhelovskaya S. V. , Asafov E. V. , Koshlyakova A. N. , Tobelko D. P. , Mezhelovsky A. D. , Sobolev A. V.
Published: December 2024

Isotopic-geochronological studies of meta-sandstones from the Vilenga Suite in the Vetreny Belt have allowed the identification of two primary and two secondary age group of detrital zircons. For the zircon group with a 207Pb/206Pb age of 2751±7 Ma, potential sources could be late granitoids (granodiorite-granite-leucogranites) extensively spread within northern part of Vodlozersky Domain. The source with a 207Pb/206Pb age of 2823±5 Ma has not been identified within the adjacent Karelian granite-greenstone terrain as of today. The source of zircon with an age of 2874 Ma are the rocks of the BADR series and adakites of the Sumozero-Kenozero greenstone belt. Previous studies of detrital zircons from the basal horizons of the Vetreny Belt section (Tokshinskaya Suite) and the underlying meta-sandstones (Kozhozerskaya Suite) revealed exactly the same primary age peaks, suggesting a stable tectonic setting in the early Paleoproterozoic and a limited unified erosion area. A minor contribution to the formation of meta-sandstones could be made by rocks of intermediate-acidic composition with an age of 2940 million years.
Olivine megacrysts in alkali-basaltoid dikes of the Western Sangilen, Southeastern Tuva
Authors: Izokh A. E. , Egorova V. V. , Shelepaev R. A. , Shelepov Ya. Yu.
Published: December 2024

Large (up to 4 cm) crystals of euhedral olivine and its intergrowths with clinopyroxene were discovered in the alkali-basaltoid dikes of the Western Sangilen, South-Eastern Tuva. The composition of olivine (Mg# 81–83, NiO 0.2–0.3 wt. %) differs sharply from the composition of olivines from mantle and gabbroid parageneses. It is shown that olivine is a liquidus phase that crystallized from an alkali basaltic melt at pressures of 10–13 kbar in intermediate magma chambers located at depths of 34–43 km, which corresponds to the level of the crust-lithospheric mantle boundary for the Western Sangilen.
Extreme wind waves on the northeastern Shelf of the Black Sea
Authors: Divinsky B. V. , Saprykina Y. V.
Published: December 2024

The research objective is an investigation of extreme storm waves in the coastal zone from Volna Village (Kerch Strait area) to Adler on the north-eastern Shelf of the Black Sea over a climatic time span. The primary research method is numerical modelling using the MIKE 21 SW spectral wave model. As a result of calculations, hourly fields of spatial distributions of key wave parameters were obtained for the Black Sea area from January 1979 to December 2023, i.e., for the past 45 years. The analysis was conducted considering the separation of the wave field into two components: wind waves and swell. The research revealed that over the last 45 years, the north-eastern coast of the Black Sea experienced the impact of 41 storms with significant wave heights exceeding 5 meters. Two November storms in 2007 and 2023 were truly extreme, with significant sea wave heights reaching 9 meters and power exceeding 500 kW/m. Average heights of storm waves along the coast varied between 4-6 meters, and average power was around 150 kW/m. The highest waves developed in the areas of Anapa, Utrish, and Idokopas. Average values of heights and powers of wind waves showed a general tendency to decrease when moving from the northwest coast to the southeast, while swell, on the contrary, increased. Several relatively homogeneous sections in terms of the development of wind waves and swell were identified in the coastal zone. In the structure of average storm waves between Volna and Anapa, wind waves absolutely dominate. Between Cape Myskhako and Idokopas, the contribution of wind waves to the total wave energy exceeds swell by 2–2.5 times. Between Arkhipo-Osipovka and Tuapse, the energy of wind waves slightly surpasses the energy of swell. Further, south of Tuapse, the contribution of swell becomes predominant. In terms of the ratio of the contribution of wind waves and swell along the coast, two distinct regions stand out: near Anapa, the overall wave climate is determined by wind waves, while in Adler, it is determined by swell.
Analisis Kesiapsiagaan Ibu Rumah Tangga dalam Pencegahan Stunting Ditinjau Pemberian ASI Eksklusif dan Sanitasi
Authors: Wiratama Rifki , Wulandari Endah Sri
Published: December 2024

Stunting is a condition that indicates growth failure in children due to chronic malnutrition, recurrent infections, and inadequate psychosocial stimulation. If left untreated, stunting can lead to impaired physical development and hurt cognitive development, educational performance, and even economic productivity in adulthood. This study aims to analyze housewives' preparedness to prevent stunting, viewed from aspects of sanitation and exclusive breastfeeding in Cikunir Village, Tasikmalaya Regency. The research method used is a quantitative approach with a descriptive-analytical design. Data were collected from 39 housewife respondents who have children under five years old through questionnaires and direct observation. Data analysis was performed using the Spearman correlation test. The study results show that exclusive breastfeeding has a significant positive correlation with the occurrence of stunting (p-value=0.042), as does access to clean water (p-value=0.001) and access to restrooms (p-value=0.016), while the type of restroom was not significant (p-value=0.060). These findings indicate that access to clean water has a highly significant relationship with the incidence of stunting in children under five years old. However, the type of restroom was not significantly associated with stunting. In conclusion, the low prevalence of stunting in the study location is likely due to the limited practice of exclusive breastfeeding and sanitation access. Furthermore, efforts should be prioritized to increase the coverage of exclusive breastfeeding, provide adequate sanitation access, and raise community awareness about restroom sanitation and the surrounding environment to further reduce the incidence of stunting.