bluuebunny/crossref_metadata_2025 huggingface dataset:
PENGEMBANGAN ALAT PENYEDOT MADU KLANCENG HUTAN MENGGUNAKAN DINAMO SOCK DRAT 160 PSI DAN SPEED CONTROLLER
Authors: Syaputra Edo , Retno Eka Pramitasari  , Mohammad Munib Rosadi  , Dian Anisa Rokhmah Wati
Published: June 2024

Pengembangan alat penyedot madu menggunakan dinamo sock drat 160 Psi dan Speed Controller ini dilakukan karena pada alat terdahulu masih terdapat kekurangan, yaitu lambatnya proses pemanenan karena pompa dinamo terlalu kecil dan wadah madu hanya berukuran 500 ml. Sehingga pengembangan dengan menggunakan dinamo sock drat 160 Psi ini dilakukan agar alat dapat lebih maksimal dan cepat dalam proses pemanenan madu.Metode penelitian yang digunakan adalah R&D (Research & Development) sebuah metode untuk menghasilkan produk baru atau mengembangkan produk yang sudah ada dan digunakan sebagai pengujian keefektifan produk tersebut. Tujuan dari penelitian ini adalah untuk mengetahui desain dari pengembangan alat penyedot madu dan untuk mengetahui waktu penyedotan dari alat. Hasil pembuatan dan perakitan dari pengembangan alat penyedot madu ini telah sesuai dengan rancangan yang sudah dibuat. Uji validasi alat juga dilakukan. Untuk hasil uji validasi alat dari uji fungisonalnya, alat ini mendapatkan rata – rata nilai 87,5% dengan kriteria sangat baik. Untuk uji kelayakannya, alat ini mendapatkan rata – rata nilai 100% dengan kriteria nilai sangat baik. Pada saat proses uji coba alat,  media yang digunakan adalah madu. Hasil yang didapatkan dari alat ini dalam waktu 10 menit 21 detik yaitu 450 ml.
PENGARUH FRAKSI VOLUME SERAT KELAPA BERMATRIKS EPOXY TERHADAP KEKUATAN TARIK KOMPOSIT
Authors: Ubaidillah Muhammad Wahyu , Rokhmah Wati Dian Anisa , Rosadi Mohammad Munib , Irfa'I Mochmad Arif
Published: June 2024

Komposit adalah bahan gabungan dari dua bisa lebih bahan yang lainya. Komposit mempunyai rangakaian dua bisa lebih bahan yang digabung jadi satu bahan secara mikroskopis dimana bahan pembentuknya terlihat masih seperti asli dan diantaranya masih memiliki hubungan kerja sehingga mampu menunjukan sifat yang diinginkan. Penelitian ini bertujuan untuk untuk mengetahui pengaruh serat kelapa terhadap kekuatan tarik komposit dengan fraksi volume 40%, 50% dan 60% bermatrik epoxy. Data yang diperoleh dari penelitian akan dianalisis menggunakan Anova satu jalur pada aplikasi SPSS 16.0. Hasil yang diperoleh dari uji Anova satu jalur menyatakan bahwa terdapat pengaruh perbedaan fraksi volume 40%, 50% dan 60% menghasilkan sig. sebesar 0.003 lebih kecil dari 0,05 sehingga dapat di simpulkan bahwa rata-rata ke tiga uji tarik fraksi volume tersebut “berbeda” secara signifikan. Jadi dari  ketiga variasi memiliki pengaruh berbeda yang signifikan.
Ett undervisningsmaterial för att stödja elevers förståelse för programmering inom ramen för teknikämnet
Authors: Salomonsson Niklas , Wickberg Hugerth Mattias , Anderhag Per
Published: June 2024

I denna artikel diskuterar vi hur vi har använt resultat från ett mindre forskningsprojekt om programmering för att utveckla undervisningen inom teknikämnet. I forskningsprojektet såg vi att eleverna använde olika strategier när de programmerade en robot att följa en böjd linje, och att dessa strategier var olika framgångsrika för att lösa uppgiften. Resultatet från detta projekt samt våra erfarenheter av att undervisa programmering på grund- och gymnasieskolan användes för att ta fram och pröva ett undervisningsmaterial som stödjer elevers förståelse för programmering. Materialet adresserar inte enbart programmeringsspecifika begrepp, utan också för teknikämnet relevanta företeelser såsom återkopplingssystem, ändamålsenlighet och pröva och ompröva. Undervisningsmaterialet, som är grundat i den didaktiska modellen Organiserande syften, utgörs av en PowerPoint med korta lärarkommentarer.
Environmental impact assessment with rapid impact assessment matrix method: during disaster conditions
Authors: Abbasi Sina , Modibbo Umar Muhammad , Jafari Kolashlou Hamed , Ali Irfan , Kavousi Nader
Published: June 2024

In the last several decades, Iran’s ecosystem has suffered due to the careless usage of natural resources. Cities have grown in an uneven and non-normative way, and poor project management has been a major issue, particularly in large cities. An even greater number of environmental factors and engineering regulations are not relevant to projects. Because of this, in order to ascertain a project’s environmental impact, an environmental impact assessment (EIA), is required. Using the rapid impact assessment matrix (RIAM) is one method of applying it to EIA. Reducing subjectivity brings objectivity and transparency. During the COVID-19 pandemic, a thorough EIA was carried out for the Tehran project utilizing the RIAM and other possibilities. This research is the first to combine the methodology that was discussed during the incident. Through the use of the RIAM technique, the environmental impact of COVID-19 was to be quantified in this inquiry. The research examined lockdown procedures and the COVID-19 pandemic to create an EIA indicator. In a real-world case study conducted in Tehran, Iran, the impact of the initiative was evaluated using the RIAM methodology during the COVID-19 epidemic. The results demonstrated that COVID-19 had both beneficial and harmful effects. Decision-makers were effectively informed about the COVID-19 pandemic’s environmental consequences on people and the environment, as well as how to minimize negative effects, according to the EIA technique that used RIAM. This is the first research to integrate the EIA during a crisis, such as the COVID-19 pandemic, with the RIAM approach.
Teachers’ mathematical work based on examples presented in the teaching of algebra in secondary education
Authors: Henríquez-Rivas Carolina , Verdugo-Hernández Paula
Published: June 2024

Both international examination results and scientific evidence related to the teaching and learning of school algebra point to the necessity for analyzing mathematical practice in the classroom. In this context, we have formulated the research objective of characterizing the mathematical work that teachers favor based on the examples that they implement in the teaching of topics within the domain of secondary school algebra. To this end, this study is situated within the interpretive paradigm utilizing an instrumental collective case study approach. The study design entails the selection of two representative cases of mathematics teachers in Chilean schools, with the objective of understanding and describing their mathematical work in the secondary school classroom based on the examples they present. The results show that the first teacher utilizes varied examples that activate distinct forms of mathematical thinking, promoting the activation of both instrumental and discursive genesis. In contrast, the second teacher follows a more traditional approach, with the use of examples to illustrate and motivate, and a direct presentation of knowledge, activating primarily semiotic genesis, in which a transition between the numerical and the algebraic is lacking. Ultimately, the results highlight the importance of deeper consideration of the choice of examples in the teaching of algebra and how these examples can influence students’ learning. Furthermore, additional ideas are put forward for future work in this line of research associated with the use of examples in the classroom.
Analysis of changes in water quality and treatment effectiveness of seven major river basins in China from 2001 to 2020
Authors: Yang Qin , Chen Jingsheng , Liu Yuyi , Li Yangguang , Zhang Haigang , Zhang Jing , Sun Xiao , Lu Mingyang , Ma Rongqian , Wu Yanlin
Published: June 2024

The seven major river basins (the Yangtze River, the Yellow River, the Pearl River, the Songhua River, the Huai River, the Hai River and the Liao River) are the most important surface water resources in China, but there is a lack of quantitative analyses of water quality change trends, horizontal comparisons of governance effects, and systematic review of effective policies since the 21st century. Based on the water resources bulletin and environmental status bulletin issued by government departments, the changes in water quality, pollutant indicators and treatment effectiveness of seven major basins from 2001 to 2020 have been scientifically analyzed using mathematical and statistical methods. (1) Over the period 2001 to 2020, the overall water quality in the seven major river basins exhibited a gradual improvement. Different basins demonstrated varied growth values for Grade I-III water, reduction values for Grade IV-V, and inferior Grade V water. (2) Between 2001 and 2020, changes in sewage discharge volume and types led to adjustments in the main pollutant indicators of the seven basins. (3) The ranking of the pollution degree in the seven major basins exhibited dynamic changes but also remained relatively stable during specific periods or years. (4) Assessing the average annual growth rate of Grade I-III water and the average annual reduction rate of Grade IV-V and inferior Grade V water, the Huai River basin demonstrated the most outstanding governance effectiveness, while the Liao River basin, the Yellow River basin, and the Songhua River basin also achieved notable treatment results. (5) The improvement in water quality across the seven major river basins can be attributed to scientific planning, enhanced policies and regulations, surge in investment in water conservancy infrastructure, heightened environmental protection awareness, application of green production technology. To sum up, the research findings not only provide a scientific foundation for the governance and protection of the seven major basins but also offer a valuable reference for other developing countries to strike a balance between economic development and environmental protection.
Size distribution of brake wear particulate matter based on a brake dynamometer investigation
Authors: Zhong Chongzhi , Sun Jiaxing , Liu Zishu , Niu Haomiao , Zhang Jing , Liang Xiaoyu , Yin Jiawei , Wu Lin , Peng Jianfei , Zhang Qijun , Mao Hongjun
Published: June 2024

A brake dynamometer has been modified to accurately study the concentration and size distribution of wear particles in different testing conditions. The test equipment was a charged low-pressure impactor ELPI+ from Dekati, Finland. 29 test conditions were defined based on speed, acceleration and initial brake temperature. Additionally, five different types of brake pads were selected for testing to provide a more comprehensive understanding of the particle size distribution characteristics of brake wear particles. The results showed that the mass of BWPs was unimodal in the range of 0.01–8.11 μm, with peak sizes at 2–5 μm or >8.11 μm, and particles of 0.5–3.0 μm accounted for an average of 49.09% of the total particulate mass, while particles with sizes of 3.0–8.11 μm accounted for an average of 49.72% of the total particulate mass. The number of particles emitted by abrasion had a bimodal distribution, with one in the nucleation mode and the other in the accumulation mode, with peak sizes of <10 nm and 1 μm, respectively; the nucleation mode particles accounted for an average of 60.11% of the total PN10, and the ultrafine particles accounted for an average of 82.15%.
The role of the gut microbiota in tumor, immunity, and immunotherapy
Authors: Xie Yuyan , Liu Fang
Published: June 2024

In recent years, with the deepening understanding of the gut microbiota, it has been recognized to play a significant role in the development and progression of diseases. Particularly in gastrointestinal tumors, the gut microbiota influences tumor growth by dysbiosis, release of bacterial toxins, and modulation of host signaling pathways and immune status. Immune checkpoint inhibitors (ICIs) have greatly improved cancer treatment efficacy by enhancing immune cell responses. Current clinical and preclinical studies have demonstrated that the gut microbiota and its metabolites can enhance the effectiveness of immunotherapy. Furthermore, certain gut microbiota can serve as biomarkers for predicting immunotherapy responses. Interventions targeting the gut microbiota for the treatment of gastrointestinal diseases, especially colorectal cancer (CRC), include fecal microbiota transplantation, probiotics, prebiotics, engineered bacteria, and dietary interventions. These approaches not only improve the efficacy of ICIs but also hold promise for enhancing immunotherapy outcomes. In this review, we primarily discuss the role of the gut microbiota and its metabolites in tumors, host immunity, and immunotherapy.
Effect of cyclic compression on the micromechanical properties of a Zr-based metallic glass
Authors: Wang Anwei , Wang Yang , Zhu Hongwu , Sun Hanxiao , Li Yansen
Published: June 2024

In this study, the effect of cyclic compression on the micromechanical properties of a Zr-based metallic glass (MG) was investigated via nanoindentation. Cyclic compression significantly softened the surface of the sample, with a maximum hardness loss of 19.93%. The number of cyclic compression passes had a greater effect on the hardness of the sample than the cyclic compression load. The elastic modulus exhibited a nonlinear variation upon increasing the cyclic loading or number of passes at a lower loading rate due to the coupling effect of loading rate and cyclic compression treatment. Then, the serration behavior and strain rate sensitivity analysis were applied. The calculated m-values obtained for MGs were all negative and gradually tended to zero upon further cyclic compression treatment. This demonstrated the weakening effect of cyclic compression on the strain rate sensitivity of MG, and the underlying mechanism was discussed. This study provides a process reference for studying the fatigue failure behaviors of MGs from the perspective of mechanical properties, which is useful for understanding their fatigue generation.
Streamlining intersectoral provision of real-world health data: a service platform for improved clinical research and patient care
Authors: Hoffmann Katja , Nesterow Igor , Peng Yuan , Henke Elisa , Barnett Daniela , Klengel Cigdem , Gruhl Mirko , Bartos Martin , Nüßler Frank , Gebler Richard , Grummt Sophia , Seim Anne , Bathelt Franziska , Reinecke Ines , Wolfien Markus , Weidner Jens , Sedlmayr Martin
Published: June 2024

Introduction

Obtaining real-world data from routine clinical care is of growing interest for scientific research and personalized medicine. Despite the abundance of medical data across various facilities — including hospitals, outpatient clinics, and physician practices — the intersectoral exchange of information remains largely hindered due to differences in data structure, content, and adherence to data protection regulations. In response to this challenge, the Medical Informatics Initiative (MII) was launched in Germany, focusing initially on university hospitals to foster the exchange and utilization of real-world data through the development of standardized methods and tools, including the creation of a common core dataset. Our aim, as part of the Medical Informatics Research Hub in Saxony (MiHUBx), is to extend the MII concepts to non-university healthcare providers in a more seamless manner to enable the exchange of real-world data among intersectoral medical sites.

Methods

We investigated what services are needed to facilitate the provision of harmonized real-world data for cross-site research. On this basis, we designed a Service Platform Prototype that hosts services for data harmonization, adhering to the globally recognized Health Level 7 (HL7) Fast Healthcare Interoperability Resources (FHIR) international standard communication format and the Observational Medical Outcomes Partnership (OMOP) common data model (CDM). Leveraging these standards, we implemented additional services facilitating data utilization, exchange and analysis. Throughout the development phase, we collaborated with an interdisciplinary team of experts from the fields of system administration, software engineering and technology acceptance to ensure that the solution is sustainable and reusable in the long term.

Results

We have developed the pre-built packages “ResearchData-to-FHIR,” “FHIR-to-OMOP,” and “Addons,” which provide the services for data harmonization and provision of project-related real-world data in both the FHIR MII Core dataset format (CDS) and the OMOP CDM format as well as utilization and a Service Platform Prototype to streamline data management and use.

Conclusion

Our development shows a possible approach to extend the MII concepts to non-university healthcare providers to enable cross-site research on real-world data. Our Service Platform Prototype can thus pave the way for intersectoral data sharing, federated analysis, and provision of SMART-on-FHIR applications to support clinical decision making.
A case report of AQP4-IgG-seropositive refractory neuromyelitis optica spectrum disorder patient with Sjögren’s syndrome and pancytopenia treated with inebilizumab
Authors: Li Shasha , Gao Yuting , He Yang , Zhang Zhaoxu
Published: June 2024

Patients with neuromyelitis optica spectrum disorder (NMOSD) coexisting with both Sjögren’s syndrome (SS) and pancytopenia are exceptionally rare. There is no study on the treatment of such patients. We presented a case of AQP4-IgG seropositive refractory NMOSD patient combined with SS and pancytopenia with significant response to inebilizumab. In 2017 the 49-year-old female patient was diagnosed with SS and pancytopenia without any treatment. In August 2022, she had a sudden onset of lower limbs weakness, manifested as inability to walk, accompanied by urinary incontinence. After receiving methylprednisolone and cyclophosphamide, she regained the ability to walk. In February 2023, she suffered from weakness of both lower limbs again and paralyzed in bed, accompanied by retention of urine and stool, and loss of vision in both eyes. After receiving methylprednisolone and three plasmapheresis, the condition did not further worsen, but there was no remission. In March 2023, the patient was admitted to our hospital and was formally diagnosed with AQP4-IgG seropositive NMOSD combined with SS and pancytopenia. After receiving two 300 mg injections of inebilizumab, not only the symptoms of NMOSD improved significantly, but also the symptoms of concurrent SS and pancytopenia. In the cases of AQP4-IgG seropositive NMOSD who have recurrent episodes and are comorbid with other autoimmune disorders, inebilizumab may be a good choice.
Closed-loop transcutaneous auricular vagus nerve stimulation for the improvement of upper extremity motor function in stroke patients: a study protocol
Authors: Xiao Xue-Zhen , Li Rongdong , Xu Chengwei , Liang Siqi , Yang Meng , Zhong Haili , Huang Xiyan , Ma Jingjing , Xie Qiuyou
Published: June 2024

Background

Transcutaneous auricular vagus nerve stimulation (taVNS) has garnered attention for stroke rehabilitation, with studies demonstrating its benefits when combined with motor rehabilitative training or delivered before motor training. The necessity of concurrently applying taVNS with motor training for post-stroke motor rehabilitation remains unclear. We aimed to investigate the necessity and advantages of applying the taVNS concurrently with motor training by an electromyography (EMG)-triggered closed-loop system for post-stroke rehabilitation.

Methods

We propose a double-blinded, randomized clinical trial involving 150 stroke patients assigned to one of three groups: concurrent taVNS, sequential taVNS, or sham control condition. In the concurrent group, taVNS bursts will synchronize with upper extremity motor movements with EMG-triggered closed-loop system during the rehabilitative training, while in the sequential group, a taVNS session will precede the motor rehabilitative training. TaVNS intensity will be set below the pain threshold for both concurrent and sequential conditions and at zero for the control condition. The primary outcome measure is the Fugl-Meyer Assessment of Upper Extremity (FMA-UE). Secondary measures include standard upper limb function assessments, as well as EMG and electrocardiogram (ECG) features.

Ethics and dissemination

Ethical approval has been granted by the Medical Ethics Committee, affiliated with Zhujiang Hospital of Southern Medical University for Clinical Studies (2023-QX-012-01). This study has been registered on ClinicalTrials (NCT05943431). Signed informed consent will be obtained from all included participants. The findings will be published in peer-reviewed journals and presented at relevant stakeholder conferences and meetings.

Discussion

This study represents a pioneering effort in directly comparing the impact of concurrent taVNS with motor training to that of sequential taVNS with motor training on stroke rehabilitation. Secondly, the incorporation of an EMG-triggered closed-loop taVNS system has enabled the automation and individualization of both taVNS and diverse motor training tasks—a novel approach not explored in previous research. This technological advancement holds promise for delivering more precise and tailored training interventions for stroke patients. However, it is essential to acknowledge a limitation of this study, as it does not delve into examining the neural mechanisms underlying taVNS in the context of post-stroke rehabilitation.
Comprehensive evaluation methods for translating BCI into practical applications: usability, user satisfaction and usage of online BCI systems
Authors: Pan He , Ding Peng , Wang Fan , Li Tianwen , Zhao Lei , Nan Wenya , Fu Yunfa , Gong Anmin
Published: June 2024

Although brain-computer interface (BCI) is considered a revolutionary advancement in human-computer interaction and has achieved significant progress, a considerable gap remains between the current technological capabilities and their practical applications. To promote the translation of BCI into practical applications, the gold standard for online evaluation for classification algorithms of BCI has been proposed in some studies. However, few studies have proposed a more comprehensive evaluation method for the entire online BCI system, and it has not yet received sufficient attention from the BCI research and development community. Therefore, the qualitative leap from analyzing and modeling for offline BCI data to the construction of online BCI systems and optimizing their performance is elaborated, and then user-centred is emphasized, and then the comprehensive evaluation methods for translating BCI into practical applications are detailed and reviewed in the article, including the evaluation of the usability (including effectiveness and efficiency of systems), the evaluation of the user satisfaction (including BCI-related aspects, etc.), and the evaluation of the usage (including the match between the system and user, etc.) of online BCI systems. Finally, the challenges faced in the evaluation of the usability and user satisfaction of online BCI systems, the efficacy of online BCI systems, and the integration of BCI and artificial intelligence (AI) and/or virtual reality (VR) and other technologies to enhance the intelligence and user experience of the system are discussed. It is expected that the evaluation methods for online BCI systems elaborated in this review will promote the translation of BCI into practical applications.
A lightweight Yunnan Xiaomila detection and pose estimation based on improved YOLOv8
Authors: Wang Fenghua , Tang Yuan , Gong Zaipeng , Jiang Jin , Chen Yu , Xu Qiang , Hu Peng , Zhu Hailong
Published: June 2024

Introduction

Yunnan Xiaomila is a pepper variety whose flowers and fruits become mature at the same time and multiple times a year. The distinction between the fruits and the background is low and the background is complex. The targets are small and difficult to identify.

Methods

This paper aims at the problem of target detection of Yunnan Xiaomila under complex background environment, in order to reduce the impact caused by the small color gradient changes between xiaomila and background and the unclear feature information, an improved PAE-YOLO model is proposed, which combines the EMA attention mechanism and DCNv3 deformable convolution is integrated into the YOLOv8 model, which improves the model’s feature extraction capability and inference speed for Xiaomila in complex environments, and achieves a lightweight model. First, the EMA attention mechanism is combined with the C2f module in the YOLOv8 network. The C2f module can well extract local features from the input image, and the EMA attention mechanism can control the global relationship. The two complement each other, thereby enhancing the model’s expression ability; Meanwhile, in the backbone network and head network, the DCNv3 convolution module is introduced, which can adaptively adjust the sampling position according to the input feature map, contributing to stronger feature capture capabilities for targets of different scales and a lightweight network. It also uses a depth camera to estimate the posture of Xiaomila, while analyzing and optimizing different occlusion situations. The effectiveness of the proposed method was verified through ablation experiments, model comparison experiments and attitude estimation experiments.

Results

The experimental results indicated that the model obtained an average mean accuracy (mAP) of 88.8%, which was 1.3% higher than that of the original model. Its F1 score reached 83.2, and the GFLOPs and model sizes were 7.6G and 5.7MB respectively. The F1 score ranked the best among several networks, with the model weight and gigabit floating-point operations per second (GFLOPs) being the smallest, which are 6.2% and 8.1% lower than the original model. The loss value was the lowest during training, and the convergence speed was the fastest. Meanwhile, the attitude estimation results of 102 targets showed that the orientation was correctly estimated exceed 85% of the cases, and the average error angle was 15.91°. In the occlusion condition, 86.3% of the attitude estimation error angles were less than 40°, and the average error angle was 23.19°.

Discussion

The results show that the improved detection model can accurately identify Xiaomila targets fruits, has higher model accuracy, less computational complexity, and can better estimate the target posture.
Urban environmental monitoring and health risk assessment introducing a fuzzy intelligent computing model
Authors: Wang Weijia , Guan Xin , Peng Xiaoyan , Wang Zeyu , Liang Xinyi , Zhu Junfan
Published: June 2024

Introduction

To enhance the precision of evaluating the impact of urban environments on resident health, this study introduces a novel fuzzy intelligent computing model designed to address health risk concerns using multi-media environmental monitoring data.

Methods

Three cities were selected for the study: Beijing (B City), Kunming (K City), and Wuxi (W City), representing high, low, and moderate pollution levels, respectively. The study employs a Fuzzy Inference System (FIS) as the chosen fuzzy intelligent computing model, synthesizing multi-media environmental monitoring data for the purpose of urban health risk assessment.

Results

(1) The model reliably estimates health risks across diverse cities and environmental conditions. (2) There is a positive correlation between PM2.5 concentrations and health risks, though the impact of noise levels varies by city. In cities B, K, and W, the respective correlation coefficients are 0.65, 0.55, and 0.7. (3) The Root Mean Square Error (RMSE) values for cities B, K, and W, are 0.0132, 0.0125, and 0.0118, respectively, indicating that the model has high accuracy. The R2 values for the three cities are 0.8963, 0.9127, and 0.9254, respectively, demonstrating the model’s high explanatory power. The residual values for the three cities are 0.0087, 0.0075, and 0.0069, respectively, indicating small residuals and demonstrating robustness and adaptability. (4) The model’s p-values for the Indoor Air Quality Index (IAQI), Thermal Comfort Index (TCI), and Noise Pollution Index (NPI) all satisfy p < 0.05 for the three cities, affirming the model’s credibility in estimating health risks under varied urban environments.

Discussion

These results showcase the model’s ability to adapt to diverse geographical conditions and aid in the accurate assessment of existing risks in urban settings. This study significantly advances environmental health risk assessment by integrating multidimensional data, enhancing the formulation of comprehensive environmental protection and health management strategies, and providing scientific support for sustainable urban planning.
Wet markets in Southeast Asia and access to healthy diets
Authors: Hofman Margot , Trevenen-Jones Ann
Published: June 2024

Hunger and malnutrition in all forms continues to rise in Africa and Asia. Urban and rural communities’ diets in Southeast Asia (SEA) are increasingly unhealthy, with consumption influenced by affordability and convenience. The cost of a healthy diet is a major barrier to accessing healthy foods in SEA. Wet markets are key places in food environments where people buy and sell a variety of foods. They are especially important for food and nutrition insecure communities. This mini narrative review explores the role that wet markets, in SEA food environments, play in providing local communities with access to healthy foods. Fourteen peer-review papers, published in English between 2017 and 2022, were identified during screening and analysed according to six food environment domains. Findings highlight that convenient access to wet markets facilitates access to fruits and vegetables in peri urban and urban areas. Fresh foods, most notably fruits, were viewed as being more expensive than processed foods which in turn influenced purchasing behavior. Divergent findings were presented in the identified papers regarding affordability of food in wet markets. Concerns about food quality and the use of chemicals and pesticides were raised. This review was constrained by several factors including the lack of consistent and meaningful definitions and typologies of the varied forms of wet markets. Looking ahead, better defined interpretations of wet markets can enhance the development and refinement of appropriate policies and actions and comparison of wet markets, in respect of access to diverse, healthy foods, vendor practices and consumer food choices.
Affect and Ethics in Mike Malloy’s Insure the Life of an Ant
Authors: Silk Gerald
Published: June 2024

This essay examines a little-known but important installation entitled Insure the Life of an Ant, conceived by artist Mike Malloy and displayed at the O.K. Harris Gallery in New York in April of 1972. This provocative and idiosyncratic piece confronted gallery-goers, who became viewer–participants, with the option of killing or saving a live ant displayed like a sculpture on a pedestal, either by pushing a button or not. The artist made the piece, which can function almost like a psychology experiment, to engender a “moral dilemma”. I explore the particular role of affect in a participatory art installation, distinct from response to inanimate art. I investigate the roles of emotion and reason in dealing with the work; whether ratiocination can be considered an “anti-affect”; and how the tension between competing thoughts and feelings helped create a psychological drama. The essay looks at how an art space can operate as a zone of moral exceptionalism to encourage questionable actions. It also locates the piece in relation to the emergence of a more behaviorist art in the early 1970s, as discussed by critic Gregory Battcock, and the larger notion of postmodernism. Other contexts investigated include art and animal rights and issues of sentience and speciesism; social and military violence, including capital punishment and the Vietnam War; the 1961 Milgram experiment; Hannah Arendt’s concept of the “banality of evil” as a Nazi war criminal defense; and other works of art involving maltreatment or violence toward both human and non-human animals, including those by Marina Abramović, Marco Evaristti, and Edward and Nancy Reddin Kienholz.
“Lost in Flowers & Foolery”: A Gendered Reading of the 9th Earl of Devon’s Flower Watercolors
Authors: Stewart James Thomas
Published: June 2024

William Courtenay, 3rd Viscount Courtenay and 9th Earl of Devon (1768–1835), has been most remembered for his romantic relationship with author and slave owner, William Beckford (1760–1844), which scandalized London society in 1784. However, the 9th Earl’s life after this event has received little attention despite his artistic contributions to the built environment of his ancestral home of Powderham Castle in Devon. In the 1790s, he created a series of flower watercolors on paper and cabinets under the supervision of his drawing master, William Marshall Craig (c.1765–1827). These artworks complicate ideas about gendered expectations of amateur artistic subjects, with flower painting being largely understood as a feminine accomplishment. This article explores the Earl’s watercolors in the context of the spaces at Powderham to argue they are evidence of his effeminate behavior and participation in female activities alongside his thirteen sisters. The association of these objects with a man attracted to those of his own sex contribute to studies of queerness, amateur art, and the country house in the late eighteenth century.
Sex, Sign, Subversion: Symbolist Art and Male Homosexuality in 19th-Century Europe
Authors: Vanover Ty
Published: June 2024

There is something queer about Symbolism. Art historians have long acknowledged the links between Symbolist aesthetics and contemporaneous ideas about human sexuality, and even a cursory examination of artworks by male Symbolist artists working across the continent reveals an eyebrow-raising number of muscled nudes, lithe ephebes, and intimate male couplings. The sensual male body could register the artist’s erotic desire, even as he put it forth as an idealized emblem of transcendental truth. But perhaps Symbolism’s queerness extended beyond subject matter. Scholars have argued that Symbolism was in part defined by a subversive approach to visual semiotics: a severing—we might say a queering—of the ties binding a sign to its established cultural meaning. Similarly, male homosexual subcultures were sustained by endowing established signs and pictures with a uniquely queer significance. This paper seeks to tease out the relationship between Symbolist aesthetics and male homosexuality in terms of a shared sensibility towards pictorial interpretation. Taking as a case study the work of the Swedish Symbolist artist Eugène Jansson, I argue that Symbolism held appeal for homosexual artists precisely because queer subcultures were primed to read subversive meaning into normative pictures. Offering a new reading of Symbolism’s sexual valences, I contextualize the movement’s attendant artworks within the broader cultural landscape of homosexual signs and symbols and articulate the parallels between Symbolist approaches to the image and queer modes of seeing in the late nineteenth century.
The Clinical Usability Evaluation of an Attachable Video Laryngoscope in the Simulated Tracheal Intubation Scenario: A Manikin Study
Authors: Lee Won-Jun , Lee Hee-Young , Kim Sun-Ju , Lee Kang-Hyun
Published: June 2024

The aim of this study was to assess the usefulness of an attachable video laryngoscope (AVL) by attaching a camera and a monitor to a conventional Macintosh laryngoscope (CML). Normal and tongue edema airway scenarios were simulated using a manikin. Twenty physicians performed tracheal intubations using CML, AVL, Pentax Airwayscope® (AWS), and McGrath MAC® (MAC) in each scenario. Ten physicians who had clinical experience in using tracheal intubation were designated as the skilled group, and another ten physicians who were affiliated with other departments and had little clinical experience using tracheal intubation were designated as the unskilled group. The time required for intubation and the success rate were recorded. The degree of difficulty of use and glottic view assessment were scored by participants. All 20 participants successfully completed the study. There was no difference in tracheal intubation success rate and intubation time in the normal airway scenario in both skilled and unskilled groups. In the experienced group, AWS had the highest success rate (100%) in the tongue edema airway scenario, followed by AVL (60%), MAC (60%), and CML (10%) (p = 0.001). The time required to intubate using AWS was significantly shorter than that with AVL (10.2 s vs. 19.2 s) or MAC (10.2 s vs. 20.4 s, p = 0.007). The difficulty of using AVL was significantly lower than that of CML (7.8 vs. 2.8; p < 0.001). For the experienced group, AVL was interpreted as being inferior to AWS but better than MAC. Similarly, in the unskilled group, AVL had a similar success rate and tracheal intubation time as MAC in the tongue edema scenario, but this was not statistically significant. The difficulty of using AVL was significantly lower than that of CML (8.8 vs. 3.3; p < 0.001). AVL may be an alternative for VL.
Classification of Ameloblastoma, Periapical Cyst, and Chronic Suppurative Osteomyelitis with Semi-Supervised Learning: The WaveletFusion-ViT Model Approach
Authors: Liang Bohui , Qin Hongna , Nong Xiaolin , Zhang Xuejun
Published: June 2024

Ameloblastoma (AM), periapical cyst (PC), and chronic suppurative osteomyelitis (CSO) are prevalent maxillofacial diseases with similar imaging characteristics but different treatments, thus making preoperative differential diagnosis crucial. Existing deep learning methods for diagnosis often require manual delineation in tagging the regions of interest (ROIs), which triggers some challenges in practical application. We propose a new model of Wavelet Extraction and Fusion Module with Vision Transformer (WaveletFusion-ViT) for automatic diagnosis using CBCT panoramic images. In this study, 539 samples containing healthy (n = 154), AM (n = 181), PC (n = 102), and CSO (n = 102) were acquired by CBCT for classification, with an additional 2000 healthy samples for pre-training the domain-adaptive network (DAN). The WaveletFusion-ViT model was initialized with pre-trained weights obtained from the DAN and further trained using semi-supervised learning (SSL) methods. After five-fold cross-validation, the model achieved average sensitivity, specificity, accuracy, and AUC scores of 79.60%, 94.48%, 91.47%, and 0.942, respectively. Remarkably, our method achieved 91.47% accuracy using less than 20% labeled samples, surpassing the fully supervised approach’s accuracy of 89.05%. Despite these promising results, this study’s limitations include a low number of CSO cases and a relatively lower accuracy for this condition, which should be addressed in future research. This research is regarded as an innovative approach as it deviates from the fully supervised learning paradigm typically employed in previous studies. The WaveletFusion-ViT model effectively combines SSL methods to effectively diagnose three types of CBCT panoramic images using only a small portion of labeled data.
Post-Acute Sequelae of SARS-CoV-2 Infection (PASC) for Patients—3-Year Follow-Up of Patients with Chronic Kidney Disease
Authors: Filev Rumen , Lyubomirova Mila , Bogov Boris , Kalinov Krassimir , Hristova Julieta , Svinarov Dobrin , Garev Alexander , Rostaing Lionel
Published: June 2024

Post-acute sequelae of SARS-CoV-2 (PASC) is a significant health concern, particularly for patients with chronic kidney disease (CKD). This study investigates the long-term outcomes of individuals with CKD who were infected with COVID-19, focusing on their health status over a three-year period post-infection. Data were collected from both CKD and non-CKD patients who survived SARS-CoV-2 infection and were followed for three years as part of a research study on the impact, prognosis, and consequences of COVID-19 infection in CKD patients. In this prospective cohort study, we analyzed clinical records, laboratory findings, and patient-reported outcomes assessed at intervals during follow-up. The results indicated no permanent changes in renal function in any of the groups analyzed, although patients without CKD exhibited faster recovery over time. Furthermore, we examined the effect of RAAS-blocker therapy over time, finding no influence on PASC symptoms or renal function recovery. Regarding PASC symptoms, most patients recovered within a short period, but some required prolonged follow-up and specialized post-recovery management. Following up with patients in the post-COVID-19 period is crucial, as there is still insufficient information and evidence regarding the long-term effects, particularly in relation to CKD.
Correlation between DWI-ASPECTS Score, Ischemic Stroke Volume on DWI, Clinical Severity and Short-Term Prognosis: A Single-Center Study
Authors: Dogariu Oana Andreea , Gheorman Veronica , Dogariu Ioan , Berceanu Mihaela Corina , Albu Carmen Valeria , Gheonea Ioana Andreea
Published: June 2024

Ischemic stroke is a significant public health concern, with its incidence expected to double over the next 40 years, particularly among individuals over 75 years old. Previous studies, such as the DAWN trial, have highlighted the importance of correlating clinical severity with ischemic stroke volume to optimize patient management. Our study aimed to correlate the clinical severity of ischemic stroke, as assessed by the NIHSS score, with ischemic stroke volume measured using DWI, and short-term prognosis quantified by the mRS score at discharge. Conducted at the largest hospital in Gorj County from January 2023 to December 2023, this study enrolled 43 consecutive patients with acute ischemic stroke. In our patient cohort, we observed a strong positive correlation between NIHSS score and ischemic stroke volume (Spearman correlation coefficient = 0.982, p < 0.01), and a strong negative correlation between ASPECTS-DWI score and mRS score (Spearman correlation coefficient = −0.952, p < 0.01). Multiple linear regression analysis revealed a significant collective relationship between ASPECTS score, ischemic stroke volume, and NIHSS score (F(1, 41) = 600.28, p < 0.001, R2 = 0.94, R2adj = 0.93). These findings underscore the importance of DWI in assessing ischemic stroke severity and prognosis, warranting further investigation for its integration into clinical practice.
The Utility of Heartrate and Heartrate Variability Biofeedback for the Improvement of Interoception across Behavioural, Physiological and Neural Outcome Measures: A Systematic Review
Authors: Wareing Lettie , Readman Megan Rose , Longo Matthew R. , Linkenauger Sally A. , Crawford Trevor J.
Published: June 2024

Interoceptive dysfunctions are increasingly implicated in a number of physical and mental health conditions. Accordingly, there is a pertinent need for therapeutic interventions which target interoceptive deficits. Heartrate and heartrate variability biofeedback therapy (HR(V)-BF), interventions which train individuals to regulate their cardiovascular signals and constrain these within optimal parameters through breathing, could enhance the functioning of interoceptive pathways via stimulation of the vagus nerve. Consequently, this narrative systematic review sought to synthesise the current state of the literature with regard to the potential of HR(V)-BF as an interoceptive intervention across behavioural, physiological and neural outcome measures related to interoception. In total, 77 papers were included in this review, with the majority using physiological outcome measures. Overall, findings were mixed with respect to improvements in the outcome measures after HR(V)-BF. However, trends suggested that effects on measures related to interoception were stronger when resonance frequency breathing and an intense treatment protocol were employed. Based on these findings, we propose a three-stage model by which HR(V)-BF may improve interoception which draws upon principles of interoceptive inference and predictive coding. Furthermore, we provide specific directions for future research, which will serve to advance the current knowledge state.
Transcriptomic Profile of Mouse Brain Ageing in Early Developmental Stages
Authors: Kulis Karolina , Tabury Kevin , Benotmane Mohammed Abderrafi , Polanska Joanna
Published: June 2024

Ageing is a continuous process that can cause neurodevelopmental changes in the body. Several studies have examined its effects, but few have focused on how time affects biological processes in the early stages of brain development. As studying the changes that occur in the early stages of life is important to prevent age-related neurological and psychiatric disorders, we aim to focus on these changes. The transcriptomic markers of ageing that are common to the analysed brain regions of C57Bl/6J mice were identified after conducting two-way ANOVA tests and effect size analysis on the time courses of gene expression profiles in various mouse brain regions. A total of 16,374 genes (59.9%) significantly changed their expression level, among which 7600 (27.8%) demonstrated tissue-dependent differences only, and 1823 (6.7%) displayed time-dependent and tissue-independent responses. Focusing on genes with at least a large effect size gives the list of potential biomarkers 12,332 (45.1%) and 1670 (6.1%) genes, respectively. There were 305 genes that exhibited similar significant time response trends (independently of the brain region). Samples from an 11-day-old mouse embryo validated the identified early-stage brain ageing markers. The overall functional analysis revealed tRNA and rRNA processing in the mitochondrion and contact activation system (CAS), as well as the kallikrein/kinin system (KKS), together with clotting cascade and defective factor F9 activation being affected by ageing. Most ageing-related pathways were significantly enriched, especially those that are strongly connected to development processes and neurodegenerative diseases.
Review of Soil Creep Characteristics and Advances in Modelling Research
Authors: Liu Yanchao , Huang Feng , Cao Yanhui , Jin Fang , Wang Guihe , Hou Wei
Published: June 2024

Creep is recognised to be an important physical property of soils, exerting a profound influence on the stability of structures. In order to gain a comprehensive understanding of the advancements and focal points in soil creep research, the relevant literature was accessed from the Web of Science Core Collection database, totalling 3907 papers (as of 25 March 2024). Statistical analyses on publication volume, keyword co-occurrence, and clustering were conducted using the visualization software VOSviewer (1.6.20). The current hotspots in soil creep research were identified, and a systematic review was undertaken on the influencing factors of soil creep and the corrective methods of creep models. The research findings indicate that the number of papers on creep research exhibits a trend of increase followed by a decrease over time. Developed countries, such as those in Europe and America, initiated research in this field earlier than developing countries like China. Currently, the research focus is primarily centred on creep models. Significant differences exist in the creep deformation of soils under different influencing factors, with soil microstructure, moisture content, and stress path being important factors affecting soil creep deformation. Creep deformation in unsaturated soils primarily considers the influence of matric suction, while indoor creep tests are mainly conducted based on vertical loading, which differs significantly from the stress conditions experienced by soils in engineering construction sites. Currently, adjustments to soil parameters are mainly made through single-factor adjustments involving stress, time, damage, and matric suction to determine creep models under specific influencing factors, and then to modify the models accordingly. However, research on the creep deformation mechanism and creep models under multiple factors is relatively limited. Future research directions are expected to focus on the microscopic scale of creep mechanisms and multi-factor creep models.