bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Tables from Preclinical Efficacy of the Anti-Hepatocyte Growth Factor Antibody Ficlatuzumab in a Mouse Brain Orthotopic Glioma Model Evaluated by Bioluminescence, PET, and MRI
Authors: Mittra Erik S. , Fan-Minogue Hua , Lin Frank I. , Karamchandani Jason , Sriram Venkataraman , Han May , Gambhir Sanjiv S.
Published: April 2023

Supplementary Tables - PDF file 86K, Supplementary Table 1. Overall results of 2nd experiment shown as percent change from baseline by experimental group: Control, Low Dose, and High Dose. Supplementary Table 2. Mitotic activity and Ki-67 labeling in the 3 animals from each group that had their brain excised for pathology. Mitotic activity was assessed, by counting mitotic figures in ten high powered (400x) fields, in each of the animals in the most proliferative areas of tumor. Ki-67 labeling was assessed semi-quantitatively
Supplementary Figures from Preclinical Efficacy of the Anti-Hepatocyte Growth Factor Antibody Ficlatuzumab in a Mouse Brain Orthotopic Glioma Model Evaluated by Bioluminescence, PET, and MRI
Authors: Mittra Erik S. , Fan-Minogue Hua , Lin Frank I. , Karamchandani Jason , Sriram Venkataraman , Han May , Gambhir Sanjiv S.
Published: April 2023

Supplementary Figures - PDF file 110K, Supplementary Figure 1. Dose titration curves of ficlatuzumab. The numbers in parenthesis are the median survival in days. Supplementary Figure 2. combination therapy of ficlatuzumab and temozolomide studied in an intracranial U87 MG xenograft mouse model. The numbers in parenthesis are the median survival in days. Supplementary Figure 3. Comparison of U87 MG parental and U87 MG-Luc2 cells showing similarity in in vitro (a) and in vivo (b) characteristics. Supplementary Figure 4. Change in weight (mean � standard deviation) over the course of the experiment in the control, low-dose, and high-dose groups. Results shown are normalized to the baseline value. The p-values shown are the results of the ANOVA for each group. In this case, there were no significant changes in weight
Supplementary Figure Legend from Preclinical Efficacy of the Anti-Hepatocyte Growth Factor Antibody Ficlatuzumab in a Mouse Brain Orthotopic Glioma Model Evaluated by Bioluminescence, PET, and MRI
Authors: Mittra Erik S. , Fan-Minogue Hua , Lin Frank I. , Karamchandani Jason , Sriram Venkataraman , Han May , Gambhir Sanjiv S.
Published: April 2023

Supplementary Figure Legend - PDF file 60K, Supplementary figure legend
Supplemental Figure Legend from Effect of Aromatase Inhibition on Functional Gene Modules in Estrogen Receptor–Positive Breast Cancer and Their Relationship with Antiproliferative Response
Authors: Gao Qiong , Patani Neill , Dunbier Anita K. , Ghazoui Zara , Zvelebil Marketa , Martin Lesley-Ann , Dowsett Mitch
Published: April 2023

Supplemental Figure Legend from Effect of Aromatase Inhibition on Functional Gene Modules in Estrogen Receptor–Positive Breast Cancer and Their Relationship with Antiproliferative Response
Supplementary Table 4 from PI3K Pathway Activation Provides a Novel Therapeutic Target for Pediatric Ependymoma and Is an Independent Marker of Progression-Free Survival
Authors: Rogers Hazel A. , Mayne Cerys , Chapman Rebecca J. , Kilday John-Paul , Coyle Beth , Grundy Richard G.
Published: April 2023

PDF file - 31K, Summary of univariate survival statistics for factors analyzed, for an association with progression free survival, across the ependymoma cohort. A Kaplan Meier with a log rank test was used. Only factors with a p value less than 0.25 were used in multivariate suvival analysis.
Supplementary Table 3 from PI3K Pathway Activation Provides a Novel Therapeutic Target for Pediatric Ependymoma and Is an Independent Marker of Progression-Free Survival
Authors: Rogers Hazel A. , Mayne Cerys , Chapman Rebecca J. , Kilday John-Paul , Coyle Beth , Grundy Richard G.
Published: April 2023

PDF file - 44K, Summary of the immunohistochemistry undertaken across the ependymoma cohort.
Supplementary Table 3 from Identification of Promiscuous KIF20A Long Peptides Bearing Both CD4+ and CD8+ T-cell Epitopes: KIF20A-Specific CD4+ T-cell Immunity in Patients with Malignant Tumor
Authors: Tomita Yusuke , Yuno Akira , Tsukamoto Hirotake , Senju Satoru , Kuroda Yasuhiro , Hirayama Masatoshi , Irie Atsushi , Kawahara Kenta , Yatsuda Junji , Hamada Akinobu , Jono Hirofumi , Yoshida Koji , Tsunoda Takuya , Kohrogi Hirotsugu , Yoshitake Yoshihiro , Nakamura Yusuke , Shinohara Masanori , Nishimura Yasuharu
Published: April 2023

Supplementary Table 3 - PDF file 33K, Results of the immunohistochemical analysis of KIF20A in head and neck tumor
Supplementary Table 1 from PI3K Pathway Activation Provides a Novel Therapeutic Target for Pediatric Ependymoma and Is an Independent Marker of Progression-Free Survival
Authors: Rogers Hazel A. , Mayne Cerys , Chapman Rebecca J. , Kilday John-Paul , Coyle Beth , Grundy Richard G.
Published: April 2023

PDF file - 1016K, The table lists genes displaying a significant difference in mRNA expression between tumors from different locations, identified using an ANOVA test. mRNA data originally published by Johnson et al. 2010 (Geo accession number GSE21687) was used for analysis.
Supplementary Table 1 from Identification of Promiscuous KIF20A Long Peptides Bearing Both CD4+ and CD8+ T-cell Epitopes: KIF20A-Specific CD4+ T-cell Immunity in Patients with Malignant Tumor
Authors: Tomita Yusuke , Yuno Akira , Tsukamoto Hirotake , Senju Satoru , Kuroda Yasuhiro , Hirayama Masatoshi , Irie Atsushi , Kawahara Kenta , Yatsuda Junji , Hamada Akinobu , Jono Hirofumi , Yoshida Koji , Tsunoda Takuya , Kohrogi Hirotsugu , Yoshitake Yoshihiro , Nakamura Yusuke , Shinohara Masanori , Nishimura Yasuharu
Published: April 2023

Supplementary Table 1 - PDF file 19K, Binding algorithm scores of KIF20A-derived peptides for HLA-class II molecules
Supplementary Figure 4 from Identification of Promiscuous KIF20A Long Peptides Bearing Both CD4+ and CD8+ T-cell Epitopes: KIF20A-Specific CD4+ T-cell Immunity in Patients with Malignant Tumor
Authors: Tomita Yusuke , Yuno Akira , Tsukamoto Hirotake , Senju Satoru , Kuroda Yasuhiro , Hirayama Masatoshi , Irie Atsushi , Kawahara Kenta , Yatsuda Junji , Hamada Akinobu , Jono Hirofumi , Yoshida Koji , Tsunoda Takuya , Kohrogi Hirotsugu , Yoshitake Yoshihiro , Nakamura Yusuke , Shinohara Masanori , Nishimura Yasuharu
Published: April 2023

Supplementary Figure 4 - PDF file 105K, Induction of KIF20A-A2466-75 SP-specific CTLs in mice immunized with KIF20A60-84-LP
Supplementary Figure 3 from Identification of Promiscuous KIF20A Long Peptides Bearing Both CD4+ and CD8+ T-cell Epitopes: KIF20A-Specific CD4+ T-cell Immunity in Patients with Malignant Tumor
Authors: Tomita Yusuke , Yuno Akira , Tsukamoto Hirotake , Senju Satoru , Kuroda Yasuhiro , Hirayama Masatoshi , Irie Atsushi , Kawahara Kenta , Yatsuda Junji , Hamada Akinobu , Jono Hirofumi , Yoshida Koji , Tsunoda Takuya , Kohrogi Hirotsugu , Yoshitake Yoshihiro , Nakamura Yusuke , Shinohara Masanori , Nishimura Yasuharu
Published: April 2023

Supplementary Figure 3 - PDF file 157K, Enhanced induction of KIF20A-SP-specific CTLs by KIF20A-LP-specific CD4+ T-cells
Supplementary Figure 2 from Identification of Promiscuous KIF20A Long Peptides Bearing Both CD4+ and CD8+ T-cell Epitopes: KIF20A-Specific CD4+ T-cell Immunity in Patients with Malignant Tumor
Authors: Tomita Yusuke , Yuno Akira , Tsukamoto Hirotake , Senju Satoru , Kuroda Yasuhiro , Hirayama Masatoshi , Irie Atsushi , Kawahara Kenta , Yatsuda Junji , Hamada Akinobu , Jono Hirofumi , Yoshida Koji , Tsunoda Takuya , Kohrogi Hirotsugu , Yoshitake Yoshihiro , Nakamura Yusuke , Shinohara Masanori , Nishimura Yasuharu
Published: April 2023

Supplementary Figure 2 - PDF file 39K, Induction of KIF20A-LPs-specific Th cells from healthy donors
Supplementary Table 1 from RG7212 Anti-TWEAK mAb Inhibits Tumor Growth through Inhibition of Tumor Cell Proliferation and Survival Signaling and by Enhancing the Host Antitumor Immune Response
Authors: Yin Xuefeng , Luistro Leopoldo , Zhong Hua , Smith Melissa , Nevins Tom , Schostack Kathleen , Hilton Holly , Lin Tai-An , Truitt Theresa , Biondi Denise , Wang Xiaoqian , Packman Kathryn , Rosinski Jim , Berkofsky-Fessler Windy , Tang Jian-Ping , Pant Saumya , Geho David , Vega-Harring Suzana , DeMario Mark , Levitsky Hy , Simcox Mary
Published: April 2023

PDF file, 29K, Lead antibodies have identical binding properties and neutralizing activities.
Supplementary Figure Legends and Table Legends and Methods from RG7212 Anti-TWEAK mAb Inhibits Tumor Growth through Inhibition of Tumor Cell Proliferation and Survival Signaling and by Enhancing the Host Antitumor Immune Response
Authors: Yin Xuefeng , Luistro Leopoldo , Zhong Hua , Smith Melissa , Nevins Tom , Schostack Kathleen , Hilton Holly , Lin Tai-An , Truitt Theresa , Biondi Denise , Wang Xiaoqian , Packman Kathryn , Rosinski Jim , Berkofsky-Fessler Windy , Tang Jian-Ping , Pant Saumya , Geho David , Vega-Harring Suzana , DeMario Mark , Levitsky Hy , Simcox Mary
Published: April 2023

PDF file, 132K.
Supplementary Table 3 from Phase I Safety, Pharmacokinetic, and Pharmacodynamic Study of SAR245409 (XL765), a Novel, Orally Administered PI3K/mTOR Inhibitor in Patients with Advanced Solid Tumors
Authors: Papadopoulos Kyriakos P. , Tabernero Josep , Markman Ben , Patnaik Amita , Tolcher Anthony W. , Baselga José , Shi Weiliang , Egile Coumaran , Ruiz-Soto Rodrigo , Laird A. Douglas , Miles Dale , LoRusso Patricia M.
Published: April 2023

PDF file - 89KB, Supplementary Table 3. Reduction in Phosphoinositide 3-kinase and Mammalian Target of Rapamycin Complex 1 (mTORC1)/mTORC2 Pathway Signaling in Paired Tumor Biopsies.
Supplementary Table 2 from Phase I Safety, Pharmacokinetic, and Pharmacodynamic Study of SAR245409 (XL765), a Novel, Orally Administered PI3K/mTOR Inhibitor in Patients with Advanced Solid Tumors
Authors: Papadopoulos Kyriakos P. , Tabernero Josep , Markman Ben , Patnaik Amita , Tolcher Anthony W. , Baselga José , Shi Weiliang , Egile Coumaran , Ruiz-Soto Rodrigo , Laird A. Douglas , Miles Dale , LoRusso Patricia M.
Published: April 2023

PDF file - 70KB, Supplementary Table 2. Grade 3/4 Adverse Events that Occurred in ≥2% of Patients.
Supplementary Figure 1 from Integrative Genomic Analysis of Temozolomide Resistance in Diffuse Large B-Cell Lymphoma
Authors: Leshchenko Violetta V. , Kuo Pei-Yu , Jiang Zewei , Thirukonda Venu K. , Parekh Samir
Published: April 2023

PDF file - 190K, MGMT mRNA level is a poor predictor of sensitivity to TMZ in DLBCL.
Supplementary Table 1 from A Comparative Analysis of Prognostic Factor Models for Follicular Lymphoma Based on a Phase III Trial of CHOP–Rituximab versus CHOP + 131Iodine—Tositumomab
Authors: Press Oliver W. , Unger Joseph M. , Rimsza Lisa M. , Friedberg Jonathan W. , LeBlanc Michael , Czuczman Myron S. , Kaminski Mark , Braziel Rita M. , Spier Catherine , Gopal Ajay K. , Maloney David G. , Cheson Bruce D. , Dakhil Shaker R. , Miller Thomas P. , Fisher Richard I.
Published: April 2023

PDF file 54K, Supplementary Table 1: Results of Multivariable Model of All Statistically Significant Factors for Both PFS and OS from Univariate Analyses
Supplementary information from Targeting Src and Tubulin in Mucinous Ovarian Carcinoma
Authors: Liu Tao , Hu Wei , Dalton Heather J. , Choi Hyun Jin , Huang Jie , Kang Yu , Pradeep Sunila , Miyake Takahito , Song Jian H. , Wen Yunfei , Lu Chunhua , Pecot Chad V. , Bottsford-Miller Justin , Zand Behrouz , Jennings Nicholas B. , Ivan Cristina , Gallick Gary E. , Baggerly Keith A. , Hangauer David G. , Coleman Robert L. , Frumovitz Michael , Sood Anil K.
Published: April 2023

PDF file 106K, Table S1. Molecules whose expression significantly differed between cells treated with KX-01 and control cells in RMUG-S cells Table S2. Molecules whose expression significantly differed between cells treated with KX-01 and control cells in RMUG-L cells
Supplementary Figure Legend from Controlled Local Delivery of CTLA-4 Blocking Antibody Induces CD8+ T-Cell–Dependent Tumor Eradication and Decreases Risk of Toxic Side Effects
Authors: Fransen Marieke F. , van der Sluis Tetje C. , Ossendorp Ferry , Arens Ramon , Melief Cornelis J.M.
Published: April 2023

PDF file - 41K
Supplementary Table 1 from Improved Survival with HPV among African Americans with Oropharyngeal Cancer
Authors: Worsham Maria J. , Stephen Josena K. , Chen Kang Mei , Mahan Meredith , Schweitzer Vanessa , Havard Shaleta , Divine George
Published: April 2023

PDF file - 68K, Supplemental Table 1: Multivariable associations with late stage.
Supplementary Figure 1F from Evaluation of Progression-Free Survival as a Surrogate Endpoint for Survival in Chemotherapy and Targeted Agent Metastatic Colorectal Cancer Trials
Authors: Sidhu Roger , Rong Alan , Dahlberg Steve
Published: April 2023

PDF file - 40 KB, Trials with anti-EGFR therapy, WT KRAS subgroup
Supplementary Figure 1A from Evaluation of Progression-Free Survival as a Surrogate Endpoint for Survival in Chemotherapy and Targeted Agent Metastatic Colorectal Cancer Trials
Authors: Sidhu Roger , Rong Alan , Dahlberg Steve
Published: April 2023

PDF file - 65 KB, Overall survival (OS) hazard ratios (HR) versus progression free survival (PFS) HRs - Unweighted Analysis. (A) All selected trials.
CCR Translation for This Article from Prevalence and Characteristics of MUTYH-Associated Polyposis in Patients with Multiple Adenomatous and Serrated Polyps
Authors: Guarinos Carla , Juárez Miriam , Egoavil Cecilia , Rodríguez-Soler María , Pérez-Carbonell Lucía , Salas Ramón , Cubiella Joaquín , Rodríguez-Moranta Francisco , de-Castro Luisa , Bujanda Luis , Serradesanferm Anna , Nicolás-Pérez David , Herráiz Maite , Fernández-Bañares Fernando , Herreros-de-Tejada Alberto , Aguirre Elena , Balmaña Judith , Rincón María-Luisa , Pizarro Angeles , Polo-Ortiz Francisco , Castillejo Adela , Alenda Cristina , Payá Artemio , Soto José-Luis , Jover Rodrigo
Published: April 2023

CCR Translation for This Article from Prevalence and Characteristics of MUTYH-Associated Polyposis in Patients with Multiple Adenomatous and Serrated Polyps
Supplementary Table 1 from Tumor Suppressive Effects of Bromodomain-Containing Protein 7 (BRD7) in Epithelial Ovarian Carcinoma
Authors: Park Young-Ae , Lee Jeong-Won , Kim Hye-Sun , Lee Yoo-Young , Kim Tae-Joong , Choi Chel Hun , Choi Jung-Joo , Jeon Hye-Kyung , Cho Young Jae , Ryu Ji Yoon , Kim Byoung-Gie , Bae Duk-Soo
Published: April 2023

PDF - 57K, Information of the cell lines used in experiments.
Supplementary Figure 1 from Nab-Paclitaxel Is an Active Drug in Preclinical Model of Pediatric Solid Tumors
Authors: Zhang Libo , Marrano Paula , Kumar Sushil , Leadley Michael , Elias Evelyn , Thorner Paul , Baruchel Sylvain
Published: April 2023

PDF file - 229K, Supplementary Figure 1. Expression of SPARC and PTEN in neuroblastoma cell lines. SPARC and PTEN expression were assessed in a panel of eight neuroblastoma cell lines by Western Blot. For Western blot analysis, 50 microg protein was resolved over 10% polyacrylamide gels and transferred to a nitrocellulose membrane. The blot was blocked in blocking buffer (5% non-fat dry milk/1� Tween 20 in TBS) for 1 h at room temperature, incubated with polyclonal primary antibodies against SPARC (Cell Signaling Technology) and PTEN (Cell Signaling Technology) overnight at 4 {degree}C. The blot was then incubated with appropriate horseradish peroxidase conjugated secondary antibody and detected by enhanced chemiluminescence and autoradiography using X-ray film. beta-actin was detected on the same membrane and used as a loading control
Supplementary Figure 2 from Tumor Suppressive Effects of Bromodomain-Containing Protein 7 (BRD7) in Epithelial Ovarian Carcinoma
Authors: Park Young-Ae , Lee Jeong-Won , Kim Hye-Sun , Lee Yoo-Young , Kim Tae-Joong , Choi Chel Hun , Choi Jung-Joo , Jeon Hye-Kyung , Cho Young Jae , Ryu Ji Yoon , Kim Byoung-Gie , Bae Duk-Soo
Published: April 2023

PDF - 1091K, A, Western blot analysis was used to determine expression levels of BRD7 in the tumor samples from xenografts that were transfected with BRD7 plasmid or mock vector. B, Semi-quantitative analysis was performed on the basis of relative BRD7/ beta-actin density level using the Image J program. Individual lysates were loaded onto the gel. M1-M6 includes xenografts that were transfected with mock vectors. B1-B6 includes xenografts that were transfected with BRD7 plasmid.
Supplementary Figure Legends from Profound Prevention of Experimental Brain Metastases of Breast Cancer by Temozolomide in an MGMT-Dependent Manner
Authors: Palmieri Diane , Duchnowska Renata , Woditschka Stephan , Hua Emily , Qian Yongzhen , Biernat Wojciech , Sosińska-Mielcarek Katarzyna , Gril Brunilde , Stark Andreas M. , Hewitt Stephen M. , Liewehr David J. , Steinberg Seth M. , Jassem Jacek , Steeg Patricia S.
Published: April 2023

PDF file - 96KB
Supplementary Table 3 from Functional Heterogeneity of Cancer-Associated Fibroblasts from Human Colon Tumors Shows Specific Prognostic Gene Expression Signature
Authors: Herrera Mercedes , Islam Abul B.M.M.K. , Herrera Alberto , Martín Paloma , García Vanesa , Silva Javier , Garcia Jose M. , Salas Clara , Casal Ignacio , de Herreros Antonio García , Bonilla Félix , Peña Cristina
Published: April 2023

XLS file - 5815K, Significant DE genes between "L & M" and "H & EH" groups.
Supplementary Figure 2 from Profound Prevention of Experimental Brain Metastases of Breast Cancer by Temozolomide in an MGMT-Dependent Manner
Authors: Palmieri Diane , Duchnowska Renata , Woditschka Stephan , Hua Emily , Qian Yongzhen , Biernat Wojciech , Sosińska-Mielcarek Katarzyna , Gril Brunilde , Stark Andreas M. , Hewitt Stephen M. , Liewehr David J. , Steinberg Seth M. , Jassem Jacek , Steeg Patricia S.
Published: April 2023

PDF file - 113KB, MGMT expression status in Jimt-1-Br3 cells predicts sensitivity to temozolomide.
Supplementary Figure 4 from Functional Heterogeneity of Cancer-Associated Fibroblasts from Human Colon Tumors Shows Specific Prognostic Gene Expression Signature
Authors: Herrera Mercedes , Islam Abul B.M.M.K. , Herrera Alberto , Martín Paloma , García Vanesa , Silva Javier , Garcia Jose M. , Salas Clara , Casal Ignacio , de Herreros Antonio García , Bonilla Félix , Peña Cristina
Published: April 2023

PDF file - 2087K, Prognostic value confirmation of "CAF signature" included genes.
Supplementary Figure Legend from Inhibition of DNA Double-Strand Break Repair by the Dual PI3K/mTOR Inhibitor NVP-BEZ235 as a Strategy for Radiosensitization of Glioblastoma
Authors: Gil del Alcazar Carlos Rodrigo , Hardebeck Molly Catherine , Mukherjee Bipasha , Tomimatsu Nozomi , Gao Xiaohuan , Yan Jingsheng , Xie Xian-Jin , Bachoo Robert , Li Li , Habib Amyn A. , Burma Sandeep
Published: April 2023

PDF file - 70K
Supplementary Figure 5 from Inhibition of DNA Double-Strand Break Repair by the Dual PI3K/mTOR Inhibitor NVP-BEZ235 as a Strategy for Radiosensitization of Glioblastoma
Authors: Gil del Alcazar Carlos Rodrigo , Hardebeck Molly Catherine , Mukherjee Bipasha , Tomimatsu Nozomi , Gao Xiaohuan , Yan Jingsheng , Xie Xian-Jin , Bachoo Robert , Li Li , Habib Amyn A. , Burma Sandeep
Published: April 2023

PDF file - 23K, Radiosensitization of normal human astrocytes (NHA) with NVP-BEZ235.
Supplementary Figure 3 from Inhibition of DNA Double-Strand Break Repair by the Dual PI3K/mTOR Inhibitor NVP-BEZ235 as a Strategy for Radiosensitization of Glioblastoma
Authors: Gil del Alcazar Carlos Rodrigo , Hardebeck Molly Catherine , Mukherjee Bipasha , Tomimatsu Nozomi , Gao Xiaohuan , Yan Jingsheng , Xie Xian-Jin , Bachoo Robert , Li Li , Habib Amyn A. , Burma Sandeep
Published: April 2023

PDF file - 92K, NVP-BEZ235 does not interfere with the anti-tumor effects of TMZ in U87-vIII tumors.
Related Article from Acute Infection Induces a Metastatic Niche: A Double Menace for Cancer Patients
Authors: Smith Heath A. , Kang Yibin
Published: April 2023

Related Article from Acute Infection Induces a Metastatic Niche: A Double Menace for Cancer Patients
Supplementary Figure 2 from DNA Demethylating Agents Synergize with Oncolytic HSV1 against Malignant Gliomas
Authors: Okemoto Kazuo , Kasai Kazue , Wagner Benjamin , Haseley Amy , Meisen Hans , Bolyard Chelsea , Mo Xiaokui , Wehr Allison , Lehman Amy , Fernandez Soledad , Kaur Balveen , Chiocca E. Antonio
Published: April 2023

PDF file - 7683K, HSV Antigen immunohistochemistry.
Supplementary Figure 1 from DNA Demethylating Agents Synergize with Oncolytic HSV1 against Malignant Gliomas
Authors: Okemoto Kazuo , Kasai Kazue , Wagner Benjamin , Haseley Amy , Meisen Hans , Bolyard Chelsea , Mo Xiaokui , Wehr Allison , Lehman Amy , Fernandez Soledad , Kaur Balveen , Chiocca E. Antonio
Published: April 2023

PDF file - 1614K, Methylated CpG sites in the Nestin promoter region of rQNestin34.5, immediately upstream of the gamma1 34.5 gene.
Supplementary Figure 3 from Targeting of NAD Metabolism in Pancreatic Cancer Cells: Potential Novel Therapy for Pancreatic Tumors
Authors: Chini Claudia C.S. , Guerrico Anatilde M. Gonzalez , Nin Veronica , Camacho-Pereira Juliana , Escande Carlos , Barbosa Maria Thereza , Chini Eduardo N.
Published: April 2023

PDF file - 51K, Effect of another NAMPT siRNA on cell growth. PaTu8988t cells were transfected with Nampt siRNA and a non-target siRNA (Control).
CCR Translation for This Article from Targeting of NAD Metabolism in Pancreatic Cancer Cells: Potential Novel Therapy for Pancreatic Tumors
Authors: Chini Claudia C.S. , Guerrico Anatilde M. Gonzalez , Nin Veronica , Camacho-Pereira Juliana , Escande Carlos , Barbosa Maria Thereza , Chini Eduardo N.
Published: April 2023

CCR Translation for This Article from Targeting of NAD Metabolism in Pancreatic Cancer Cells: Potential Novel Therapy for Pancreatic Tumors
Supplementary Table 4 from Sequential Binary Gene Ratio Tests Define a Novel Molecular Diagnostic Strategy for Malignant Pleural Mesothelioma
Authors: De Rienzo Assunta , Richards William G. , Yeap Beow Y. , Coleman Melissa H. , Sugarbaker Peter E. , Chirieac Lucian R. , Wang Yaoyu E. , Quackenbush John , Jensen Roderick V. , Bueno Raphael
Published: April 2023

XLSX file - 240K, List of the differentially expressed probes for the analysis MPM vs. other tumor types.
Supplementary Table 3 from Sequential Binary Gene Ratio Tests Define a Novel Molecular Diagnostic Strategy for Malignant Pleural Mesothelioma
Authors: De Rienzo Assunta , Richards William G. , Yeap Beow Y. , Coleman Melissa H. , Sugarbaker Peter E. , Chirieac Lucian R. , Wang Yaoyu E. , Quackenbush John , Jensen Roderick V. , Bueno Raphael
Published: April 2023

XLSX file - 42K, Results of the binary diagnostic tests in a test set analyzed by RT-PCR.
Supplementary Table 1 from Sequential Binary Gene Ratio Tests Define a Novel Molecular Diagnostic Strategy for Malignant Pleural Mesothelioma
Authors: De Rienzo Assunta , Richards William G. , Yeap Beow Y. , Coleman Melissa H. , Sugarbaker Peter E. , Chirieac Lucian R. , Wang Yaoyu E. , Quackenbush John , Jensen Roderick V. , Bueno Raphael
Published: April 2023

XLSX file - 31K, PCR primers and genes. Sequences of the primers for the differential diagnosis of MPM. Selected genes for each diagnostic test.
Supplementary Figure 1 from A Phase I Study of the HSP90 Inhibitor Retaspimycin Hydrochloride (IPI-504) in Patients with Gastrointestinal Stromal Tumors or Soft-Tissue Sarcomas
Authors: Wagner Andrew J. , Chugh Rashmi , Rosen Lee S. , Morgan Jeffrey A. , George Suzanne , Gordon Michael , Dunbar Joi , Normant Emmanuel , Grayzel David , Demetri George D.
Published: April 2023

Supplementary Figure 1 - PDF file173K, Mean (plus-minus SD) Plasma Concentrations of IPI-504, 17-AAG and 17-AG following a Single Dose of IPI-504 400 mg/m2
Supplementary Figure 1 from Sequential Binary Gene Ratio Tests Define a Novel Molecular Diagnostic Strategy for Malignant Pleural Mesothelioma
Authors: De Rienzo Assunta , Richards William G. , Yeap Beow Y. , Coleman Melissa H. , Sugarbaker Peter E. , Chirieac Lucian R. , Wang Yaoyu E. , Quackenbush John , Jensen Roderick V. , Bueno Raphael
Published: April 2023

PDF file - 188K, Heat-map of the 26-gene signature used in the sequential combination of gene expression ratio tests in the 112 thoracic samples. Probes are annotated with gene symbol on the right. Relative gene expression levels are given by the scale at the top. The red asterisk indicates the mesothelioma samples.
Supplementary Materials and Methods from Putative Predictive Biomarkers of Survival in Patients with Metastatic Pancreatic Adenocarcinoma Treated with Gemcitabine and Ganitumab, an IGF1R Inhibitor
Authors: McCaffery Ian , Tudor Yanyan , Deng Hongjie , Tang Rui , Suzuki Samuel , Badola Sunita , Kindler Hedy L. , Fuchs Charles S. , Loh Elwyn , Patterson Scott D. , Chen Li , Gansert Jennifer L.
Published: April 2023

PDF - 74K
Supplementary Figure 3 from PID1 (NYGGF4), a New Growth-Inhibitory Gene in Embryonal Brain Tumors and Gliomas
Authors: Erdreich-Epstein Anat , Robison Nathan , Ren Xiuhai , Zhou Hong , Xu Jingying , Davidson Tom B. , Schur Mathew , Gilles Floyd H. , Ji Lingyun , Malvar Jemily , Shackleford Gregory M. , Margol Ashley S. , Krieger Mark D. , Judkins Alexander R. , Jones David T.W. , Pfister Stefan M. , Kool Marcel , Sposto Richard , Asgharazadeh Shahab
Published: April 2023

PDF file - 42K, Supplemental Fig 3: PID1 also inhibits colony formation using two other plasmid expression vectors.
Supplementary Table 4 from Variation within 3′-UTRs of Base Excision Repair Genes and Response to Therapy in Colorectal Cancer Patients: A Potential Modulation of microRNAs Binding
Authors: Pardini Barbara , Rosa Fabio , Barone Elisa , Di Gaetano Cornelia , Slyskova Jana , Novotny Jan , Levy Miroslav , Garritano Sonia , Vodickova Ludmila , Buchler Tomas , Gemignani Federica , Landi Stefano , Vodicka Pavel , Naccarati Alessio
Published: April 2023

PDF file - 83K, Predicted miRNAs binding in SNPs significantly associated with OS in the study.
Supplementary Figure 3 from Accessory Cells of the Microenvironment Protect Multiple Myeloma from T-Cell Cytotoxicity through Cell Adhesion-Mediated Immune Resistance
Authors: de Haart Sanne J. , van de Donk Niels W.C.J. , Minnema Monique C. , Huang Julie H. , Aarts-Riemens Tineke , Bovenschen Niels , Yuan Huipin , Groen Richard W.J. , McMillin Douglas W. , Jakubikova Jana , Lokhorst Henk M. , Martens Anton C. , Mitsiades Constantine S. , Mutis Tuna
Published: April 2023

Supplementary Figure 3 - PDF file 55K, RGDw reduces adhesion of MM cells to accessory cells. Adherent HS-5 en HUVEC accessory cells were incubated with RGDw or an irrelevant peptide for 1hour. After washing away the unbound peptide, UM9 (A) or U266 (B) cells were added and incubated overnight. Plates were reversely centrifuged to determine adhesion to accessory cells. Results represent the mean values of triplicate cultures (+/- SEM). Differences in adhesion were tested by unpaired two tailed student's t test. *= p<0.05; **= p<0.01, ***= p<0.001
Supplementary Table 1 from Variation within 3′-UTRs of Base Excision Repair Genes and Response to Therapy in Colorectal Cancer Patients: A Potential Modulation of microRNAs Binding
Authors: Pardini Barbara , Rosa Fabio , Barone Elisa , Di Gaetano Cornelia , Slyskova Jana , Novotny Jan , Levy Miroslav , Garritano Sonia , Vodickova Ludmila , Buchler Tomas , Gemignani Federica , Landi Stefano , Vodicka Pavel , Naccarati Alessio
Published: April 2023

PDF file - 89K, Genotype/allele frequencies of 12 selected BER gene SNPs in cases and controls and risk of CRC (Multivariate logistic regression analysis).
Supplementary Figure 2 from Accessory Cells of the Microenvironment Protect Multiple Myeloma from T-Cell Cytotoxicity through Cell Adhesion-Mediated Immune Resistance
Authors: de Haart Sanne J. , van de Donk Niels W.C.J. , Minnema Monique C. , Huang Julie H. , Aarts-Riemens Tineke , Bovenschen Niels , Yuan Huipin , Groen Richard W.J. , McMillin Douglas W. , Jakubikova Jana , Lokhorst Henk M. , Martens Anton C. , Mitsiades Constantine S. , Mutis Tuna
Published: April 2023

Supplementary Figure 2 - PDF file 50K, Accessory cells protect MM cells from WT-1 specific CTLs. U266 cells were co-cultured with WT-1 specific T cells in presence and absence of different accessory cells. MM cell viability was determined 24h after addition of T cells by CS-BLI (A). Granzyme B production in the supernatant was determined by ELISA (B). Significance of inhibition of MM cell survival in the presence of accessory cells was tested by unpaired two tailed student's t test. *= p<0.05; **= p<0.01
Supplementary Figure 1 from Accessory Cells of the Microenvironment Protect Multiple Myeloma from T-Cell Cytotoxicity through Cell Adhesion-Mediated Immune Resistance
Authors: de Haart Sanne J. , van de Donk Niels W.C.J. , Minnema Monique C. , Huang Julie H. , Aarts-Riemens Tineke , Bovenschen Niels , Yuan Huipin , Groen Richard W.J. , McMillin Douglas W. , Jakubikova Jana , Lokhorst Henk M. , Martens Anton C. , Mitsiades Constantine S. , Mutis Tuna
Published: April 2023

Supplementary Figure 1 - PDF file 53K, Antigen specific, HLA-restricted and dose-dependent recognition of the MM cell lines U266 and UM9, but not of accessory cells by CD8+ and CD4+ mHag-specific CTLs. The CD4+ (A) and CD8+ (B) CTLs were co-cultured with the luc+ MM cell lines UM9 and U266 in different effector to target ratios. The HLA- and mHag typing of these MM cell lines are indicated. MM cell survival was determined 24 h after addition of T cells by CS-BLI. Results represent the mean values of triplicate cultures (+/- SEM). Results are representative of 3 independent assays. In (C and D) CD4+ (C) and CD8+ (D) CTLs were co-cultured with accessory cells. Accessory cell survival was determined 24h after addition of T cells by FACS annexine V/ propidium iodide staining of CD4 and CD8 negative cells in the co-cultures. Results are depicted as % surviving cells, measured as relative number annexin V/propidium iodide negative cells, compared to no T cells control
Supplementary Materials and Methods, Figure Legends, Figures 1 - 6, Tables 1 - 2 from Chimeric Rat/Human HER2 Efficiently Circumvents HER2 Tolerance in Cancer Patients
Authors: Occhipinti Sergio , Sponton Laura , Rolla Simona , Caorsi Cristiana , Novarino Anna , Donadio Michela , Bustreo Sara , Satolli Maria Antonietta , Pecchioni Carla , Marchini Cristina , Amici Augusto , Cavallo Federica , Cappello Paola , Pierobon Daniele , Novelli Francesco , Giovarelli Mirella
Published: April 2023

PDF file - 270KB, Supplementary Figure S1. Phenotype of in vitro generated mDCs. Supplementary Figure S2. Efficiency of transfection. Supplementary Figure S3. HuHuT-, HuRT- and RHuT-DCs from HS elicit anti-HER2 CD8 response. Supplementary Figure S4. RHuT-DCs from HER2-CP elicit anti-HER2 CD8 T cell response. Supplementary Figure S5. HuHuT DCs affects Treg cells activity. Supplementary Figure S6. HuHuT-DCs activate CD8 and CD4 T cells from CTRL-CP. Supplementary Table S1. HER2-overexpressing cancer patients. Supplementary Table S2. HER2-negative cancer patients.
Supplementary Figure 6 from HDM2 Regulation by AURKA Promotes Cell Survival in Gastric Cancer
Authors: Sehdev Vikas , Katsha Ahmed , Arras Janet , Peng Dunfa , Soutto Mohammed , Ecsedy Jeffrey , Zaika Alexander , Belkhiri Abbes , El-Rifai Wael
Published: April 2023

PDF file 179K, Frequent overexpression and direct correlation between AURKA and HDM2 in human esophageal adenocarcinoma tissues
Supplementary Figure 1 from Phase II Study of Cediranib in Patients with Advanced Gastrointestinal Stromal Tumors or Soft-Tissue Sarcoma
Authors: Judson Ian , Scurr Michelle , Gardner Kate , Barquin Elizabeth , Marotti Marcelo , Collins Barbara , Young Helen , Jürgensmeier Juliane M. , Leahy Michael
Published: April 2023

PDF file - 63KB, This figure describes the relationship between time and circulating biomarkers of VEGFR and KIT inhibition.
Supplementary Figure 4 from HDM2 Regulation by AURKA Promotes Cell Survival in Gastric Cancer
Authors: Sehdev Vikas , Katsha Ahmed , Arras Janet , Peng Dunfa , Soutto Mohammed , Ecsedy Jeffrey , Zaika Alexander , Belkhiri Abbes , El-Rifai Wael
Published: April 2023

PDF file 167K, AURKA overexpression counteracts CDDP-induced cell death in AGS cells
Supplementary Figure 3 from HDM2 Regulation by AURKA Promotes Cell Survival in Gastric Cancer
Authors: Sehdev Vikas , Katsha Ahmed , Arras Janet , Peng Dunfa , Soutto Mohammed , Ecsedy Jeffrey , Zaika Alexander , Belkhiri Abbes , El-Rifai Wael
Published: April 2023

PDF file 260K, AURKA-mediated regulation of HDM2 attenuates CDDP-induced p53 expression in GC cells
Supplementary Figure 1 from HDM2 Regulation by AURKA Promotes Cell Survival in Gastric Cancer
Authors: Sehdev Vikas , Katsha Ahmed , Arras Janet , Peng Dunfa , Soutto Mohammed , Ecsedy Jeffrey , Zaika Alexander , Belkhiri Abbes , El-Rifai Wael
Published: April 2023

PDF file 1884K, AURKA and HDM2 are frequently overexpressed in esophageal adenocarcinoma cells
Supplementary Figure 1 from A High Frequency of Activating Extracellular Domain ERBB2 (HER2) Mutation in Micropapillary Urothelial Carcinoma
Authors: Ross Jeffrey S. , Wang Kai , Gay Laurie M. , Al-Rohil Rami N. , Nazeer Tipu , Sheehan Christine E. , Jennings Timothy A. , Otto Geoff A. , Donahue Amy , He Jie , Palmer Gary , Ali Siraj , Nahas Michelle , Young Geneva , LaBrecque Elaine , Frampton Garrett , Erlich Rachel , Curran John A. , Brennan Kristina , Downing Sean R. , Yelensky Roman , Lipson Doron , Hawryluk Matthew , Miller Vincent A. , Stephens Philip J.
Published: April 2023

PDF file - 65K, Supplementary Figure 1. Tile Plot of Genomic Alterations in 64Cases on Non-micropapillary Urothelial Carcinoma.
Supplementary Table 3 from A 3-Plex Methylation Assay Combined with the FGFR3 Mutation Assay Sensitively Detects Recurrent Bladder Cancer in Voided Urine
Authors: Kandimalla Raju , Masius Roy , Beukers Willemien , Bangma Chris H. , Orntoft Torben F. , Dyrskjot Lars , van Leeuwen Nikki , Lingsma Hester , van Tilborg Angela A.G. , Zwarthoff Ellen C.
Published: April 2023

PDF file, 56K, Methylation in multiple metachronous tumors.
Supplementary Table 2 from A 3-Plex Methylation Assay Combined with the FGFR3 Mutation Assay Sensitively Detects Recurrent Bladder Cancer in Voided Urine
Authors: Kandimalla Raju , Masius Roy , Beukers Willemien , Bangma Chris H. , Orntoft Torben F. , Dyrskjot Lars , van Leeuwen Nikki , Lingsma Hester , van Tilborg Angela A.G. , Zwarthoff Ellen C.
Published: April 2023

PDF file, 19K, Sensitivity of the methylation markers for detection of different stage and grade recurrences.
Supplementary Table 1 from A 3-Plex Methylation Assay Combined with the FGFR3 Mutation Assay Sensitively Detects Recurrent Bladder Cancer in Voided Urine
Authors: Kandimalla Raju , Masius Roy , Beukers Willemien , Bangma Chris H. , Orntoft Torben F. , Dyrskjot Lars , van Leeuwen Nikki , Lingsma Hester , van Tilborg Angela A.G. , Zwarthoff Ellen C.
Published: April 2023

PDF file, 21K, Primers and probes used for the BS-SNaPshot assay and FGFR3 assay.
CCR Translation for This Article from Targeting Protein Kinase CK2 Suppresses Prosurvival Signaling Pathways and Growth of Glioblastoma
Authors: Zheng Ying , McFarland Braden C. , Drygin Denis , Yu Hao , Bellis Susan L. , Kim Hyunsoo , Bredel Markus , Benveniste Etty N.
Published: April 2023

CCR Translation for This Article from Targeting Protein Kinase CK2 Suppresses Prosurvival Signaling Pathways and Growth of Glioblastoma
Supplementary Text from Defining Risks of Taxane Neuropathy: Insights from Randomized Clinical Trials
Authors: Kudlowitz David , Muggia Franco
Published: April 2023

PDF file - 125K, Supplemental information on taxane drug properties.
Supplementary Figure 3 from A 3-Plex Methylation Assay Combined with the FGFR3 Mutation Assay Sensitively Detects Recurrent Bladder Cancer in Voided Urine
Authors: Kandimalla Raju , Masius Roy , Beukers Willemien , Bangma Chris H. , Orntoft Torben F. , Dyrskjot Lars , van Leeuwen Nikki , Lingsma Hester , van Tilborg Angela A.G. , Zwarthoff Ellen C.
Published: April 2023

PDF file, 113K, 3-plex methylation assay.
Supplementary Figure 2 from A 3-Plex Methylation Assay Combined with the FGFR3 Mutation Assay Sensitively Detects Recurrent Bladder Cancer in Voided Urine
Authors: Kandimalla Raju , Masius Roy , Beukers Willemien , Bangma Chris H. , Orntoft Torben F. , Dyrskjot Lars , van Leeuwen Nikki , Lingsma Hester , van Tilborg Angela A.G. , Zwarthoff Ellen C.
Published: April 2023

PDF file, 43K, Probability Value plot of the 3-plex methylation assay.
Supplementary Table 1 from Identification of FGFR4 as a Potential Therapeutic Target for Advanced-Stage, High-Grade Serous Ovarian Cancer
Authors: Zaid Tarrik M. , Yeung Tsz-Lun , Thompson Melissa S. , Leung Cecilia S. , Harding Tom , Co Ngai-Na , Schmandt Rosie S. , Kwan Suet-Ying , Rodriguez-Aguay Cristian , Lopez-Berestein Gabriel , Sood Anil K. , Wong Kwong-Kwok , Birrer Michael J. , Mok Samuel C.
Published: April 2023

PDF file - 2539K, Detailed protocol used for immunolocalization of FGFR4 in ovarian tumor sections
Supplementary Figure 2 from Identification of FGFR4 as a Potential Therapeutic Target for Advanced-Stage, High-Grade Serous Ovarian Cancer
Authors: Zaid Tarrik M. , Yeung Tsz-Lun , Thompson Melissa S. , Leung Cecilia S. , Harding Tom , Co Ngai-Na , Schmandt Rosie S. , Kwan Suet-Ying , Rodriguez-Aguay Cristian , Lopez-Berestein Gabriel , Sood Anil K. , Wong Kwong-Kwok , Birrer Michael J. , Mok Samuel C.
Published: April 2023

PDF file - 3119K, Effect of FGFR4 overexpression and exogenous FGF1 and on ovarian cancer cell proliferation
Supplementary Figure 6 from Inhibition of Protein Phosphatase 2A Radiosensitizes Pancreatic Cancers by Modulating CDC25C/CDK1 and Homologous Recombination Repair
Authors: Wei Dongping , Parsels Leslie A. , Karnak David , Davis Mary A. , Parsels Joshua D. , Marsh Amanda C. , Zhao Lili , Maybaum Jonathan , Lawrence Theodore S. , Sun Yi , Morgan Meredith A.
Published: April 2023

PDF file - 152K, LB100 leads to persistent radiation-induced DNA damage.
Supplementary Tables 1 - 3 from Clinical Monoclonal B Lymphocytosis versus Rai 0 Chronic Lymphocytic Leukemia: A Comparison of Cellular, Cytogenetic, Molecular, and Clinical Features
Authors: Morabito Fortunato , Mosca Laura , Cutrona Giovanna , Agnelli Luca , Tuana Giacomo , Ferracin Manuela , Zagatti Barbara , Lionetti Marta , Fabris Sonia , Maura Francesco , Matis Serena , Gentile Massimo , Vigna Ernesto , Colombo Monica , Massucco Carlotta , Recchia Anna Grazia , Bossio Sabrina , De Stefano Laura , Ilariucci Fiorella , Musolino Caterina , Molica Stefano , Di Raimondo Francesco , Cortelezzi Agostino , Tassone Pierfrancesco , Negrini Massimo , Monti Sara , Rossi Davide , Gaidano Gianluca , Ferrarini Manlio , Neri Antonino
Published: April 2023

PDF file - 175K, Supplementary Table S1. Clinical and prognostic parameters of cases analyzed by gene expression profiling arrays (45 cMBL and 115 Rai0-CLL) and by miRNA expression profiling arrays (39 cMBL and 111 Rai0-CLL). Supplementary Table S2. List of the 302 modulated genes identified by the supervised multiclass analysis comparing cMBL and Rai0-CLL samples stratified according to IGVH mutational status at the 90th percentile of false discovery rate (FDR) equal to 0. The SAM score(d) and the contrast values of each class are reported for each gene. Negative values indicates down-regulation, positive up-regulation. In bold italic are marked the eight genes that showed different modulation depending on Rai0-CLL or cMBL configuration. Supplementary Table S3. List of the 18 modulated miRNAs in the supervised multiclass analysis comparing cMBL and Rai0-CLL samples stratified according to IGVH mutational status at q-value 0. The SAM score(d) and the contrast values of each class are reported for each gene. Negative values indicates down-regulation, positive up-regulation.
Supplementary Figure 2 from A Phase I/II Trial of Pazopanib in Combination with Lapatinib in Adult Patients with Relapsed Malignant Glioma
Authors: Reardon David A. , Groves Morris D. , Wen Patrick Y. , Nabors Louis , Mikkelsen Tom , Rosenfeld Steve , Raizer Jeffrey , Barriuso Jorge , McLendon Roger E. , Suttle A. Benjamin , Ma Bo , Curtis C. Martin , Dar Mohammed M. , de Bono Johann
Published: April 2023

PDF file - 182K, Tumor reduction in 3 patients who achieved a partial response following (A) 21 days, (B) 15 months, and (C) 18 months of treatment
Supplementary Figure 1 from A Phase I/II Trial of Pazopanib in Combination with Lapatinib in Adult Patients with Relapsed Malignant Glioma
Authors: Reardon David A. , Groves Morris D. , Wen Patrick Y. , Nabors Louis , Mikkelsen Tom , Rosenfeld Steve , Raizer Jeffrey , Barriuso Jorge , McLendon Roger E. , Suttle A. Benjamin , Ma Bo , Curtis C. Martin , Dar Mohammed M. , de Bono Johann
Published: April 2023

PDF file - 179K, Study design
Supplementary Figure 1 from Deciphering the Mechanisms of Tumorigenesis in Human Pancreatic Ductal Epithelial Cells
Authors: Chang Zhe , Li Zhongkui , Wang Xiaoyang , Kang Ya'an , Yuan Yuhui , Niu Jiangong , Wang Huamin , Chatterjee Deyali , Fleming Jason B. , Li Min , Abbruzzese James L. , Chiao Paul J.
Published: April 2023

PDF file - 89K, Supplementary Fig. 1. Western blot analysis of expression levels of K-ras, Her2a, and p53- regulated p21WAF1 in β-irradiated cells.
Supplementary Materials from The Tumor-Suppressive Function of UNC5D and Its Repressed Expression in Renal Cell Carcinoma
Authors: Lu Dan , Dong Dong , Zhou Yu , Lu Min , Pang Xue-Wen , Li Yan , Tian Xiao-Jun , Zhang Yu , Zhang Jun
Published: April 2023

Supplementary materials - PDF file 40K, Supplementary materials
Supplementary Data from A Neu View of Invasive Lobular Breast Cancer
Authors: Bose Ron
Published: April 2023

Supplementary Data from A Neu View of Invasive Lobular Breast Cancer
Supplementary Table 2 from A Potent Combination of the Novel PI3K Inhibitor, GDC-0941, with Imatinib in Gastrointestinal Stromal Tumor Xenografts: Long-Lasting Responses after Treatment Withdrawal
Authors: Floris Giuseppe , Wozniak Agnieszka , Sciot Raf , Li Haifu , Friedman Lori , Van Looy Thomas , Wellens Jasmien , Vermaelen Peter , Deroose Christophe M. , Fletcher Jonathan A. , Debiec-Rychter Maria , Schöffski Patrick
Published: April 2023

PDF file - 58K, Xenografts used in GDC-0941 efficacy experiments. All mice were subcutaneously transplanted with tumor fragment on both sides.
Supplementary Methods from Colon Cancer–Specific Cytochrome P450 2W1 Converts Duocarmycin Analogues into Potent Tumor Cytotoxins
Authors: Travica Sandra , Pors Klaus , Loadman Paul M. , Shnyder Steven D. , Johansson Inger , Alandas Mohammed N. , Sheldrake Helen M. , Mkrtchian Souren , Patterson Laurence H. , Ingelman-Sundberg Magnus
Published: April 2023

Supplementary Methods - PDF file 82K, Detailed experimental procedures
Supplementary Figure 1 from A Potent Combination of the Novel PI3K Inhibitor, GDC-0941, with Imatinib in Gastrointestinal Stromal Tumor Xenografts: Long-Lasting Responses after Treatment Withdrawal
Authors: Floris Giuseppe , Wozniak Agnieszka , Sciot Raf , Li Haifu , Friedman Lori , Van Looy Thomas , Wellens Jasmien , Vermaelen Peter , Deroose Christophe M. , Fletcher Jonathan A. , Debiec-Rychter Maria , Schöffski Patrick
Published: April 2023

PDF file - 2344K, Representative images of control tumors from GIST882Ly (A-E) and GIST-DFR (F-J). The H&E staining was shown to illustrate tumor morphology (A, F). Expression of KIT (B, G), ANO1 (C, H), ETV1 (D, I) and CD44 (E, J) were studied to further characterize GIST xenograft models.
Supplementary Table 2 from HIC1 Modulates Prostate Cancer Progression by Epigenetic Modification
Authors: Zheng Jianghua , Wang Jinglong , Sun Xueqing , Hao Mingang , Ding Tao , Xiong Dan , Wang Xiumin , Zhu Yu , Xiao Gang , Cheng Guangcun , Zhao Meizhong , Zhang Jian , Wang Jianhua
Published: April 2023

PDF file - 53K, Part of genes regulated more than 2-fold in PC3HIC1 and C4-2BHIC1 cells comparison with the control
Supplementary Methods from HIC1 Modulates Prostate Cancer Progression by Epigenetic Modification
Authors: Zheng Jianghua , Wang Jinglong , Sun Xueqing , Hao Mingang , Ding Tao , Xiong Dan , Wang Xiumin , Zhu Yu , Xiao Gang , Cheng Guangcun , Zhao Meizhong , Zhang Jian , Wang Jianhua
Published: April 2023

PDF file - 238K
Figure S1 from Blood mRNA Expression Profiling Predicts Survival in Patients Treated with Tremelimumab
Authors: Saenger Yvonne , Magidson Jay , Liaw Bobby , de Moll Ellen , Harcharik Sara , Fu Yichun , Wassmann Karl , Fisher David , Kirkwood John , Oh William K. , Friedlander Philip
Published: April 2023

Figure S1 provides risk score for melanoma patients and normals.
Supplementary Figure 3 from HIC1 Modulates Prostate Cancer Progression by Epigenetic Modification
Authors: Zheng Jianghua , Wang Jinglong , Sun Xueqing , Hao Mingang , Ding Tao , Xiong Dan , Wang Xiumin , Zhu Yu , Xiao Gang , Cheng Guangcun , Zhao Meizhong , Zhang Jian , Wang Jianhua
Published: April 2023

PDF file - 904K, Restoring HIC1 expression prevents PCa metastasis by intracardiac and tail vein injections in BALB/c Nude mice
Supplementary Table 1 from A Molecular Taxonomy for Urothelial Carcinoma
Authors: Sjödahl Gottfrid , Lauss Martin , Lövgren Kristina , Chebil Gunilla , Gudjonsson Sigurdur , Veerla Srinivas , Patschan Oliver , Aine Mattias , Fernö Mårten , Ringnér Markus , Månsson Wiking , Liedberg Fredrik , Lindgren David , Höglund Mattias
Published: April 2023

XLS file - 193K, Patient and sample data
Supplementary Figure 3 from A Molecular Taxonomy for Urothelial Carcinoma
Authors: Sjödahl Gottfrid , Lauss Martin , Lövgren Kristina , Chebil Gunilla , Gudjonsson Sigurdur , Veerla Srinivas , Patschan Oliver , Aine Mattias , Fernö Mårten , Ringnér Markus , Månsson Wiking , Liedberg Fredrik , Lindgren David , Höglund Mattias
Published: April 2023

PDF file - 392K, Expression of cell adhesion genes
Supplementary Figures 1 - 2 from Molecular Photoacoustic Imaging of Follicular Thyroid Carcinoma
Authors: Levi Jelena , Kothapalli Sri-Rajashekar , Bohndiek Sarah , Yoon Joon-Kee , Dragulescu-Andrasi Anca , Nielsen Carsten , Tisma Aleksandra , Bodapati Sunil , Gowrishankar Gayatri , Yan Xinrui , Chan Carmel , Starcevic Daniela , Gambhir Sanjiv Sam
Published: April 2023

PDF file - 370K, Characterization of the probes: HPLC, MS and absorbance data
Supplementary Figure Legend from Molecular Photoacoustic Imaging of Follicular Thyroid Carcinoma
Authors: Levi Jelena , Kothapalli Sri-Rajashekar , Bohndiek Sarah , Yoon Joon-Kee , Dragulescu-Andrasi Anca , Nielsen Carsten , Tisma Aleksandra , Bodapati Sunil , Gowrishankar Gayatri , Yan Xinrui , Chan Carmel , Starcevic Daniela , Gambhir Sanjiv Sam
Published: April 2023

PDF file - 46K
Supplementary Figure 5 from Molecular Photoacoustic Imaging of Follicular Thyroid Carcinoma
Authors: Levi Jelena , Kothapalli Sri-Rajashekar , Bohndiek Sarah , Yoon Joon-Kee , Dragulescu-Andrasi Anca , Nielsen Carsten , Tisma Aleksandra , Bodapati Sunil , Gowrishankar Gayatri , Yan Xinrui , Chan Carmel , Starcevic Daniela , Gambhir Sanjiv Sam
Published: April 2023

PDF file - 380K, Ex vivo optical imaging of the BAPPA probe biodistribution
Supplementary Tables from Therapeutic Enhancement of ER Stress by Insulin-Like Growth Factor I Sensitizes Myeloma Cells to Proteasomal Inhibitors
Authors: Tagoug Inès , Jordheim Lars Petter , Herveau Stéphanie , Matera Eva-Laure , Huber Anne-Laure , Chettab Kamel , Manié Serge , Dumontet Charles
Published: April 2023

PDF file - 106K, Supplemental table 1. Antibodies used in the study; Supplemental table 2. Genes differentially expressed in MM1.S cells exposed to IGF-1 (200 ng/mL) and bortezomib (10 nM). The list indicate genes with at least a 2-fold difference in expression levels (Agilent pangenomic array)
Supplementary Figure Legend from In Vitro and In Vivo Antitumor Activity of a Novel Alkylating Agent, Melphalan-Flufenamide, against Multiple Myeloma Cells
Authors: Chauhan Dharminder , Ray Arghya , Viktorsson Kristina , Spira Jack , Paba-Prada Claudia , Munshi Nikhil , Richardson Paul , Lewensohn Rolf , Anderson Kenneth C.
Published: April 2023

PDF file - 66K