bluuebunny/crossref_metadata_2025 huggingface dataset:
Anadolu Selçuklu Dönemi Yerli ve Yabancı Kaynaklarında Anadolu’da Gıda ve Gıda Üretimi Üzerine Bir Değerlendirme
Authors: Sevim Sezai , Güllü Yusuf Alper
Published: February 2019

Anadolu Selçuklu Devleti, Türklerin Anadolu’da kurdukları ilk devlet olarak tarihimizin önemli dönüm noktalarından birini teşkil etmektedir. Türkistan’dan getirdikleri sosyal ve kültürel değerleri Anadolu’nun farklı milletlerinin inanç ve kültürleri ile yoğurarak yeni bir medeniyet ortaya çıkaran Anadolu Selçukluları, bunun yanı sıra bugün dahi bu değerler ile hoşgörü çatısı altında birlikte yaşayabilmenin temelini oluşturmuşlardır.Yaşadığımız bu topraklara böylesine bir değer katan bu büyük devleti her veçhesi ile bilmek ve anlamak tarihin önemli kırılma noktalarına hâkim olabilmek adına önemlidir. Bu çerçevede tarihimizin önemli bir kültür hazinesi olan Anadolu Selçukluları’nın sosyal ve kültürel hayatına ışık tutmak adına incelenmesi gereken bir alan da gıda, beslenme ve yemek kültürü olarak önem arz etmektedir. Bu amaçla çalışmada Anadolu Selçuklu döneminin önde gelen ana kaynaklarında tespit edilen gıda ve üretimi bilgileri yorumlanarak gıda mühendisliği perspektifinde değerlendirilmiştir.
Machine Learning Made Easy: A Review of Scikit-learn Package in Python Programming Language
Authors: Hao Jiangang , Ho Tin Kam
Published: February 2019

Machine learning is a popular topic in data analysis and modeling. Many different machine learning algorithms have been developed and implemented in a variety of programming languages over the past 20 years. In this article, we first provide an overview of machine learning and clarify its difference from statistical inference. Then, we review Scikit-learn, a machine learning package in the Python programming language that is widely used in data science. The Scikit-learn package includes implementations of a comprehensive list of machine learning methods under unified data and modeling procedure conventions, making it a convenient toolkit for educational and behavior statisticians.
I Shall Not Be Prey: Instilling Perceived Self-Efficacy Through Personal Security Training
Authors: Knaster Andrew
Published: February 2019

The world can be a dangerous place as evidenced by the 2015 riots in Baltimore, Maryland and the record high numbers of murder that occurred during those riots. People’s fear of being the prey of a violent criminal is very real and it often results in people retreating from society and avoiding situations that are perceived as dangerous. An examination of literature on perceived self-efficacy, a confident belief in one’s own ability to cope with a fearful situation, shows that through personal security and self-defense training that is designed for the particular student, perceived self-efficacy can be achieved. Students having achieved that sense are less prone to suffer from invasive negative thoughts, victimization, and avoidance behaviors that pull them out of living normal lives.
AUDIT SISTEM UNIT KESEHATAN SEKOLAH PADA SDN 4 KOTA KARANG MENGGUNAKAN COBIT 4.0
Authors: nopiansah nyata
Published: February 2019

1.PENDAHULUAN1.1 Latar BelakangSekolah dasar (disingkat SD) adalah jenjang paling dasar pada pendidikan formal diIndonesia. Sekolah dasar ditempuh dalam waktu 6 tahun, mulai dari kelas 1 sampai kelas 6.Lulusan sekolah dasar dapat melanjutkan pendidikan ke Sekolah Menengah Pertama (atausederajat). Pelajar sekolah dasar umumnya berusia 7-12 tahun. Di Indonesia, setiap warga Negara berusia 7-15 tahun-tahun wajib mengikuti pendidikan dasar, yakni sekolah dasar(atau sederajat) 6 tahun dan sekolah menengah pertama (atau sederajat) 3 tahun.Dalam setiap Sekolah Dasar selalu terdapat tim pengajar yang dipimpin oleh seorang Kepala Sekolah.
KONSTRIBUSI ORANG TUA DAN MUBALLIGH DALAM MENUMBUHKAN KARAKTER ANAK DI KAMPONG GAYAU SARAWAK MALAYSIA
Authors: IAIN Palopo Prodi_PGMI FTIK
Published: February 2019

This study ain to obtain an overview of the succes of the character development of children aged 10-12 years based on the role of islamic education from the muballigh and the contribution of parents education in gayau pantu Malaysia. The results of this study also provide an overview of islamic da'wah education and educative contributions of parents in the growth of children's character to achieve life indepedence for the generation of the nation.
Analisis Pengaruh SIM, SOP dan Jaringan Distribusi Terhadap Supply Chain Manajemen (Studi Kasus Pada PT. Lion Mentari Airlines)
Authors: Kusumaningrum Aliffah
Published: February 2019

To improve realibility and air worThere are several factors that could lead supply chain effectively, like information systems, implementation standard operating procedures and distribution network. Maintenance of air plane can be go efferective and efficient to support supply chain such as system Information,standard operating procedure,supply chain. The factor of regulation in an airlines not only involved by employees in their work environment but also support by the tight of regulation itself. The objective of this paper is to finding out whether three of factor above have impacting supply chain effectively (as partial and collective) and also define what factor that strongest affecting supply chain effectively. This study is a survey to test the hypothesis of the influence between Management Information Systems, standard operating procedures and distribution networks on the effectiveness of supply chain in the airlines PT. Lion Mentari Airlines, and the results of the survey through the questionnaire were analyzed through hypothesis testing carried out by the method of correlation and regression. the results of the analysis and testing in the study of the factors that influence the supply chain effectiveness in PT Lion Mentari Airlines, the following conclusions are obtained, the analysis shows a significant influence between management information systems on supply chain effectiveness, which means that the higher the effectiveness of information systems Management, the higher the supply chain operational effectiveness. This shows that information systems can help activities and improve the achievement of operational objectives for the company.
Enhancing Access to Physical Therapy Services for People Experiencing Poverty and Homelessness: The Lighthouse Pilot Project
Authors: Oosman Sarah , Weber Garnette , Ogunson Morenike , Bath Brenna
Published: February 2019

Purpose: Our aim was to reveal client and provider perspectives on the impact of enhancing access to physical therapy services in a primary health care community-based setting. Method: Clients of The Lighthouse Supported Living facility in Saskatoon, Saskatchewan, who accessed physical therapy services over a 4-month pilot period and health care providers (physical therapists and a nurse practitioner) provided qualitative data (through interviews and an online discussion board). Client demographics, health condition, perceived function, quality of life, and satisfaction were obtained through chart review and questionnaires. Results: Forty-seven clients ranging in age from 21 to 72 years (mean 47 y) participated in the pilot project. Most presented with a musculoskeletal issue (85.1%). Analysis of the qualitative data gathered from client and provider participants revealed the following four overarching themes: (1) complex health challenges, unmet needs; (2) overcoming access barriers and impact of physical therapy services; (3) respecting and responding to context and environment; and (4) moving forward to enhance access to physical therapy care. Conclusions: Individuals experiencing homelessness and poverty face diverse barriers to accessing physical therapy services, including transportation, cost, wait times, and geographical location. Clients who accessed physical therapy services at The Lighthouse perceived a positive impact on their overall health, function, and wellness.
Labelling a Patient’s Change Status: It’s a Confidence Game
Authors: Stratford Paul W.
Published: February 2019

Purpose: The past several decades have seen considerable interest in identifying and applying threshold change values with outcome measures commonly used by physiotherapists. The crucial question of interest to clinicians is, To what extent can valid inferences be drawn from an outcome measure’s change or improvement score? To date, typical reporting by researchers includes the presentation of a validity coefficient, often in the form of the area under a receiver operating characteristic curve, and a threshold change or improvement value. A limitation of existing work is that it does not convey the confidence that a clinician can have in a decision based on applying the proposed threshold change value. Methods: This knowledge translation article presents three questions, or building blocks, to consider when making a judgment about a patient’s change status: (1) to what extent does a measure assess change in the context of interest, (2) what is the threshold change value, and (3) how confident can a clinician be in making the correct decision about a patient’s change status when applying the threshold change value? Results: This article provides a process for combining clinical expertise with the results from threshold value studies to enhance confidence in clinical decisions about individual patients’ change status. Conclusions: The article shows how a graph can be used to efficiently translate the results from threshold value studies to convey the chance of making the correct decision about a patient’s change status.
Arquitectura copy paste
Authors: Vargas Michael
Published: February 2019

El que está libre de haber poseido un artículo de imitación que lance la primera piedra... De unas económicas pilas SONY a unas llamativas sandalias scrocs. Desde luego, haber consumido alguno de esos artículos no nos convertirá en complices de promover una cultura de copy paste que pudiera llegar al extremo de copiar un patrimonio turística entero ¿o si?. Un estudio hecho por el G-20 en 2011 determinó que la industria de la falsificación en China movió $650 mil millones al año (el PBI total de Perú es de $202 mil millones). Estos productos, que son imitaciones y remedios están en casi todas las lineas de productos importados legitimamente de China. Esto va desde repuestos de autos y aviones, a equipos electrónicos, electrodomésticos, productos farmaceúticos, de belleza, juguetes y hasta alimentos.
Pudendal neuralgia: diagnostics and treatment
Authors: Ilyashenko V I
Published: February 2019

The article considers the main causes of the occurrence of pudendal neuralgia. The criteria for diagnosing this state are described in detail. We present basic methods of treatment of pudendal neuralgia starting with comprehensive preservative treatment (physical therapy, medication, blockade), which in most cases are effective. And in case of its ineffectiveness or relapse of the pain syndrome, issues of conduction of pulsed RF-frequency therapy of the nerve are examined. Currently, the possibility of using hyaluronic acid preparations, botulinum toxin for the treatment of sexual neuropathy, as well as cryoanalgesia is being studying. The surgical decompression of the sexual nerve is possible in case of inefficient conservative treatment.
Organization Citizenship Behavor (OCB) Study on STIE Pasaman Employees
Authors: Gustika Roza , Lubis M. Saleh , M.si Asraf , Nur M
Published: February 2019

The OCB behavior is necessary to effectiveness of work in organization including Higher Education. This study looks at how how organizational culture variables and organizational commitment affect the behavior of OCB on STIE Pasaman employees. Previously, TCR were measured in these three variables. The goal is to see how the level of this variable when the research done and how the influence of independent variables to the dependent variable. The population of the research was STIE Pasaman employee, amounting to 41 people, all of whom were respondents. Measurement of variables is done through questionnaires with Likert scale. Next is calculated TCR and Multiple Linear regression testing. The results showed that the three variables still need improvement efforts. Organizational Culture and Organizational Commitment either partially or simultaneously have a positive and significant effect on OCB. The implication of this research is that STIE Pasaman's leadership still needs to work to make OCB's behavior better, and this can be done with improvements the  organizational culture and increased organizational commitment. Keywords: OCB, Organizational Culture and Organizational Commitment.
Analysis of Service Quality and Satisfaction on AMIK Kosgoro Library
Authors: Hendrayani Eka
Published: February 2019

The library serves as a supporting university tridharma in education and teaching, research, cooperative extention. Therefore, the college library in charge of collecting, processing, providing and disseminating information in accordance with the curriculum in the college concerned. In addition, the library should also try to enrich the knowledge of teaching staff / lecturers to improve the quality of student achievement. The purpose of this study to determine and explain the extent of influence the quality of library services to the level of student satisfaction as users of AMIK Kosgoro Solok library. Viewed from 5 determinations of service quality: 1) tangibles, 2) reliable services, 3) responsive service, 4) assurance services, 5) empathetic services (emphaty ). The population is the student who visited the library. The sample of the study was taken from some population with incidental sample (accidental sample) technique. The sample size is 150 students. The research method used is descriptive quantitative. Data were collected through questionnaire given to the students, then the data were analyzed by simple regression and multiple regression with the help of SPSS program. The result of research about library services is viewed from 5 service quality determinant that is tangible, reliability, responsive, assurance and emphaty affect student's satisfaction level. The conclusion of this research is library service as a whole is quite satisfactory / influential equal to 68,1% with significance 0,00 to level of student satisfaction as user of AMIK Kosgoro Solok library. 31.9% is influenced by other factors. Advice to librarians to further improve services for the future so as to achieve maximum student satisfaction level.Keywords: library, service, level of satisfaction
An Analysis Of The Influence Of Rupiah / USD Exchange Rate, Inflation and BI Rate On Indonesia Composite Index
Authors: Indah Novi Permata
Published: February 2019

Investasi pada saham dianggap memiliki tingkat risiko yang lebih besar dibandingkan dengan alternatif investasi lain seperti obligasi, deposito, dan tabungan. Oleh karena itu, investor sangat membutuhkan informasi dari pergerakan indeks harga saham pada Bursa Efek. Untuk melihat perkembangan pasar modal Indonesia salah satu indikator yang sering diguakan adalah Indeks Harga Saham Gabungan (IHSG). IHSG  dalam perkembangannya sangat rentan terhadap kondisi makro ekonomi secara umum. Penelitian ini bertujuan melihat bagaimana pengaruh faktor-faktor makro ekonomi yaitu nilai tukar rupih/USD (kurs), inflasi dan BI rate terhadap perubahaan nilai IHSG pada Bursa Efek Indonesia.Objek dalam penelitian ini adalah IHSG, nilai tukar rupih/USD (kurs), inflasi dan BI rate yang diambil dari statistik bulanan dengan nilai harga penutupan setiap bulan pada periode Januri 2011-Desember 2016. Data yang digunakan dalam peneitian ini adalah data sekunder yang diperoleh dari Bursa Efek Indonesia, dan situs resmi Bank Indonesia.  Hasil penelitian menunjukan bahawa dari ketiga faktor makro ekonomi yang diteliti, hanya nilai tukar rupih/USD (kurs) yang secara signifikan memepengaruhi IHSG, sedangakan 2 faktor makro ekonomi lain yaitu inflasi dan BI rate tidak berpengaruh signifikan terhadap perubahan nilai IHSG. Besar pengaruh dari nilai tukar rupiah/USD, Inflasi dan BI rate terhadap IHSG masing masing adalah 0,23 , -9,408 dan -100,17. Dari hasil tersebut diketahui bahawa hanya pengaruh nilai tukar rupiah/USD yang berbanding lurus terhadap nilai IHSG , sedangkan pengaruh inflasi dan BI rate terhadap IHSG berbanding terbalik.
FINANCIAL DISTRESS PREDICTED BY CASH FLOW AND LEVERAGE WITH CAPITAL INTENSITY AS MODERATING
Authors: Bernardin Deden Edward Yokeu , Tifani Tifani
Published: February 2019

The level of financial distress is a condition where the company's finances are in an unhealthy state or crisis. This study aims to examine the effect of cash flow and leverage in predicting the level of financial distress which is moderated by capital intensity at PT. Indah Karya (Persero). The research method used is descriptive verification with a quantitative approach. To assess this research, the 2013-2017 Quarterly Financial Report is used. The results showed that cash flows has a negative and significant influence in predicting the level of financial distress, leverage (debt to asset ratio) has a positive and insignificant influence in predicting the level of financial distress, capital intensity has a negative and insignificant effect in moderating the effect of cash flows on the level of financial difficulty and capital intensity has a positive and insignificant influence in moderating the influence of leverage in predicting the level of financial distress. Simultaneously cash flow and leverage in predicting the level of financial distress which is moderated by capital intensity together - have a significant effect on the condition of the level of financial distress of PT. Indah Karya (Persero). Another result found in this study is that the capital intensity variable in moderating leverage has the strongest influence in predicting the level of corporate financial distress which is seen by using an assessment of total assets to sales and debt to asset ratio. With these results, the company can use it as an early detection in the face of financial distress.

Keywords: CashFlow, Leverage, Capital Intensity, Financial distress
THE INFLUENCE OF COMPENSATION ON EMPLOYEE LOYALITY AT PT SURYA PILAR PERKASA PEKANBARU
Authors: Anuar Saiful
Published: February 2019

This research was conducted at PT. SURYA PILAR PERKASA. One way used to increase employee loyalty for companies is compensation. Compensation is a form of reward received by employees in lieu of services they have provided to the company. The purpose of this study is to determine the effect of compensation on employee loyalty PT. Surya Pillars of Might. The population in this study were 85 employees. The sample taken is the whole of the population of 85 employees. For the regression of linear analysis, the regression equation is generated as follows: Y = 6.464 + 1.421.X and the constant value of 6.464 states that if the value of X = 0 or Compensation variable does not exist, then the value of Employee Loyalty variable is 6.464. The regression coefficient of the Compensation variable is 1.421, meaning that every addition of 1 (one) variable point of Compensation, then it will increase employee loyalty equal to 1.421 times. The interpretation of the equation above is that the variable regression coefficient of Compensation (X) has a positive sign (1.421), which implies that Compensation is in line with Employee Loyalty variable, in other words that the Compensation variable has a positive effect on Employee Loyalty. Based on the value of t, obtained t-count of 2.952 at the sig level of 0.000. The calculation results show that Compensation has t arithmetic larger than t table that is 2.952> 1,988 which means Ho is rejected so Ha accepted. It can be concluded that the Compensation variable has a significant influence on employee loyalty in PT.Surya Pilar Perkasa Pekanbaru. Furthermore, R2 value of 0.669. Because this coefficient determination test obtained from simple linear regression calculation, the coefficient of determination of 0.669 or R2 x 100% by 67%. The meaning of the value has the implication that the compensation variable affects Loyalty by 67%, and the rest is influenced by other variables.

Keywords: Compensation, Loyalty
IMPLEMENTATION OF BAI ‘BITSAMAN AJIL (BAA) FINANCING TO INCREASING INCOME ON BMT AT-TAQWA MUHAMMADIYAH BANDAR BUAT BRANCH
Authors: Yenti Fitri , Febrianti Siska , Veranti Dola Olivia
Published: February 2019

The purpose of this study is to describe the procedure for the implementation of Bai ’Bitsaman Ajil (BBA) financing at BMT Taqwa Muhammadiyah Branch Bandar Buat. The data source of this study was obtained from the manager of BMT Taqwa Muhammadiyah Bandar Bandar branch. Based on the results of the research conducted by the author, that BMT At-Taqwa Muhammadiyah Bandar Buat Branch has established a financing procedure that must be met by each prospective customer starting with the customer submitting a request for financing, the Account Officer (AO) conducts a survey to the place of business and residence, Account Officer (AO) calculates customer cash flaw (cash flow), realization of financing proposals, and the latter pays installments to BMT
DISCRIMINATION, TAX CONSCIOUSNESS, AND SERVICE QUALITY TOWARDS PERCEPTION OF TAX EMBEZZLEMENT
Authors: Nurachman Indriyani Astuti , Fajar Catur Martian , Suparwo Adi
Published: February 2019

Tax fraud is a problem that often occurs in all parts of tax administration, one of which is tax evasion. As a result, the perception of taxpayers is reluctant to pay taxes. This is seen from the low awareness of taxpayers in the Bandung KPP Intermediate. The purpose of this study was to determine the effect of discrimination, awareness of taxpayers and the quality of tax services on the perception of tax evasion. This research uses descriptive verification method with a quantitative approach. The data source used is primary data as a result of distributing questionnaires to taxpayers as many as 100 respondents. Based on the results of the study showed that partially discrimination and awareness of taxpayers have no significant effect on the perception of tax evasion. But the quality of tax services has a significant effect on the perception of tax evasion. Simultaneously discrimination, awareness of taxpayers and the quality of tax services have a significant effect on the perception of tax evasion. The quality of tax services has the most influence on the perception of tax evasion with indicators of accuracy of information. From the results of the research, it is expected that tax officials are always swift and willing to provide clear and understandable information by taxpayers, so that taxpayers feel satisfied with the services provided because it can reduce tax evasion at the Intermediate Tax Office in Bandung.

Keywords: Discrimination, taxpayer awareness, tax service quality, perceptions of tax evasion
Hubungan Ukuran Lingkar Lengan Atas (LILA) dan Pertambahan Berat Badan selama Kehamilan dengan Berat Badan Lahir Bayi
Authors: Kadir Minerva Riani
Published: February 2019

Berdasarkan data dari Dinas Kesehatan Provinsi Sumatera Selatan tahun 2014, Kota Palembang memiliki kasus bayi berat lahir rendah (BBLR) terbanyak yaitu 319 kasus. Salah satu faktor yang dapat mempengaruhi berat badan bayi lahir adalah status gizi ibu hamil. Ada beberapa metode yang akurat untuk mendeteksi ibu hamil yang berisiko melahirkan BBLR yaitu dengan menilai status gizinya berdasarkan pengukuran lingkar lengan atas (LILA) dan pertambahan berat badan ibu selama kehamilan. Penelitian ini bertujuan mengetahui hubungan ukuran LILA dan pertambahan berat badan selama kehamilan dengan berat badan bayi lahir.Jenis penelitian ini adalah analitik observasional dengan desain potong lintang. Sampel penelitian ini berjumlah 125 ibu hamil yang menjalani pemeriksaan kehamilan dan kunjungan neonatal pertama (KN-1) di Puskesmas Dempo, Puskesmas Sekip dan Puskesmas 7 Ulu Palembang pada Juni 2015-Juni 2016. Data dianalisis menggunakan uji chi squaredan regresi logistik ganda.Terdapat hubungan yang sangat bermakna antara pendapatan (p = 0,000;OR = 25,636), ukuran LILA ibu hamil (p = 0,000; OR = 15,333) dan pertambahan berat badan selama kehamilan (p=0,000; OR = 47,400) dengan berat badan bayi lahir. Pertambahan berat badan ibu selama kehamilan merupakan faktor yang paling berpengaruh terhadap berat badan lahir. Setiap pertambahan 1 cm ukuran LILA ibu hamil akan menambah berat bayi lahir sebesar 61-gram dan setiap pertambahan 1 kg berat badan ibu selama hamil akan menambah berat bayi lahir sebesar 77-gram.
Hubungan Kecemasan dengan Nyeri Kepala Tipe Tegang pada Mahasiswa Program Studi Pendidikan Dokter Fakultas Kedokteran Universitas Sriwijaya Angkatan 2013
Authors: Wijaya Alifandi Abrianto , Sugiharto Henry , Zulkarnain Muhamad
Published: February 2019

Nyeri kepala tipe tegang adalah nyeri kepala bilateral yang bersifat ringan hingga sedang, menekan, mengikat, disertai fotofobia atau fonofobia, tidak berdenyut, tidak dipengaruhi oleh aktivitas fisik, dan tidak terdapat mual atau muntah. Faktor risiko dari nyeri kepala tipe tegang bervariasi antara lain usia, jenis kelamin dan kecemasan. Mahasiswa kedokteran memiliki beban belajar yang cukup berat disertai kecemasan yang tinggi. Keadaan ini diduga memiliki hubungan dengan kejadian nyeri kepala tipe tegang. Penelitian ini bertujuan untuk mengetahui hubungan kecemasan dengan nyeri kepala tipe tegang pada mahasiswa kedokteran. Jenis penelitian yang digunakan adalah penelitian analitik observasional dengan desain potong lintang. Sampel adalah semua mahasiswa Program Studi Pendidikan Dokter Fakultas Kedokteran Universitas Sriwijaya angkatan 2013 yang memenuhi kriteria inklusi. Hamilton Rating Scale for Anxiety digunakan untuk mendiagnosis kecemasan dan nyeri kepala tipe tegang didapatkan melalui wawancara menggunakan kriteria diagnosis menurut International Headache Society. Data yang diperoleh disajikan dalam bentuk tabel kemudian dianalisis menggunakan uji chi-square. Penelitian melibatkan 244 sampel yang memenuhi kriteria inklusi. Terdapat subjek perempuan sebanyak 69,3% dan subjek laki-laki sebanyak 30,7%. 151 (61,9%) mahasiswa mengalami kecemasan dan 104 (42,6%) mahasiswa mengalami nyeri kepala tipe tegang. Subjek yang menderita nyeri kepala tipe tegang sebanyak 48,3% mengalami kecemasan dan 33,3% tidak mengalami gangguan kecemasan. Hasil uji chi square menunjukkan hubungan yang bermakna antara kecemasan dengan nyeri kepala tipe tegang (p=0,030). Terdapat hubungan yang bermakna antara kecemasan dengan nyeri kepala tipe tegang pada mahasiswa Program Studi Pendidikan Dokter Fakultas Kedokteran Universitas Sriwijaya angkatan 2013.
Mekanisme Antifertilitas Fraksi Biji Pepaya pada Tikus Jantan
Authors: Nita Sri , Hayati Lusiya , Subandrate Subandrate
Published: February 2019

Biji pepaya dapat bersifat sebagai antifertilitas. Penelitian ini dilakukan untuk mengetahui senyawa dan mekanisme antifertilitas fraksi biji pepaya pada tikus jantan dari berat vesikula seminalis dan prostat serta jumlah spermatosit primer dan spermatid. Jenis penelitian eksperimental secara in vivodengan rancangan acak lengkap. Hewan uji adalah tikus jantan (Rattus norvegicusL.) galur Sprague Dawley usia 60 hari dengan berat badan 200-210 g. Dosis pemberian 100mg/kg bb selama 24 hari. Senyawa yang dikandung oleh fraksi didapat melalui uji fitokimia. Hasil penelitian memperlihatkan senyawa yang ditemukan pada fraksi nHeksan adalah steroid, terpenoid, saponin, flavonoid. Fraksi etil asetat terdapat senyawa steroid, terpenoid dan flavonoid. Fraksi etanol air mengandung senyawa terpenoid dan flavonoid. Berat vesikula seminalis dan prostat meningkat dibandingkan kontrol. Rerata jumlah spermatosit primer dan spermatid menurun secara nyata pada semua fraksi namun penurunan terendah pada fraksi nHeksan.  Dapat disimpulkan mekanisme antifertilitas fraksi biji papaya adalah melalui penurunan rerata jumlah spermatosit primer dan spermatid.
PROPOLIS OR CAFFEIC ACID PHENETHYL ESTER (CAPE) INHIBITS GROWTH AND VIABILITY IN MULTIPLE ORAL CANCER CELL LINES.
Authors: Saarem Whitney , Wang Fang Yu , Farfel Elena
Published: February 2019

Objective: Propolis is a natural antimicrobial resin from honeybee hives that contains caffeic acid phenethyl ester (CAPE), which has anti-proliferative activity against some human cancers, including colon, liver, lung and breast – although limited evidence has evaluated this potential in oral cancers. Based upon this information, the primary objective of this study was to evaluate the anti-tumor effects of CAPE against multiple well-characterized oral cancer cell lines. Methods: Using well-characterized oral cancer cell lines (SCC15, SCC25 and CAL27), CAPE was administered at 100 ug/mL to assess any effects on cellular viability or growth over three days. A normal, non-cancerous cell line (HGF-1) was also included.

Results: The results of this pilot study demonstrated that CAPE administration significantly reduced both viability and proliferation in all three oral cancer cell lines.  Viability was significantly reduced between 30.3% and 35.4% among the oral cancer cell lines (p<0.05), but remained unchanged in the HGF-1 normal cell control (p=0.878). Growth was significantly inhibited between 53.1% and 60.6% among the oral cancer cell lines (p<0.05) but was not affected in the HGF-1 normal cell control (p=0.341).

Conclusions: Although the reductions in both cellular viability and proliferation were distinct for each cell line, all exhibited a similar trend and were within a narrowly defined range. These results strongly suggest that CAPE administration had a significant and immediate effect on oral cancer growth and viability and therefore should be considered as the basis for future studies as a potential complementary and alternative therapy for oral cancer.

Key words: Caffeic Acid Phenethyl Ester (CAPE), Propolis, Oral cancer, Complementary and alternative medicine.
CERVICAL PAP SMEAR STUDY IN A TERTIARY CARE TEACHING HOSPITAL
Authors: Khushnood Mohammad , Gameti Priya Vijaykumar , Rajani Anisha , Jain Mala
Published: February 2019

Background: Mortality due to cervical cancer is also an indicator of health inequalities, as 86% of all deaths due to cervical cancer are in developing countries, low- and middle-income countries. Though Pap smear is a routine screening test, the overall sensitivity in detection of high grade squamous intraepithelial lesion (HSIL) is 70 - 80% .Pap smear is a simple, safe, non-invasive and cost effective method for the detection of pre-cancerous, cancerous and benign lesions of cervix.

Materials and Method: Around 100 cases attending gynecology OPD consented to participate were selected between age 15-60years with complaints. Pap smear was taken and was reported by cytopathologists according to the 2001 Bethesda system. All the data were manually collected and subsequently analyzed.  

Results: Maximum number of cases (37%)were seen in the age group og 31-40 years followed by 41-50 years (29%)and rest between 21-30 years (26%). 8% cases were seen in the age group of 51-60 years. NILM was reported in 48% of cases. Inflammatory smears were seen in 44% of cases. Two smears were reported as unsatisfactory.02% of cases was reported as ASCUS.LSIL was reported in 02% of cases while HSIL were reported in 01% of cases. Non specific findings were reported in 01 case.

Conclusion: This study proves that PAP stain is a simple, cheap, inexpensive and easy procedure and that using PAP stain cytological screening programs conducted in developing countries can play a major role in reducing mortality and morbidity due to Cancer Cervix.

Keywords: PAP stain, Cervix, Cancer
The Preferable Binding Pose of Canonical Butyrylcholinesterase Substrates Is Unproductive for Echothiophate
Authors: Zlobin A. S. , Zalevsky A. O. , Mokrushina Yu. A. , Kartseva O. V. , Golovin A. V. , Smirnov I. V.
Published: February 2019

In this paper, we, for the first time, describe the interaction between the butyrylcholinesterase enzyme and echothiophate, a popular model compound and an analogue of the chemical warfare agents VX and VR, at the atomistic level. Competition between the two echothiophate conformations in the active site was found using molecular modeling techniques. The first one is close to the mode of binding of the substrates of choline series (butyrylcholine and butyrylthiocholine) and is inhibitory, since it is unable to react with the enzyme. The second one is characterized by a significantly worse estimated binding affinity and is reactive. Thus, echothiophate combines the features of two types of inhibitors: competitive and suicidal. This observation will help clarify the kinetic reaction scheme in order to accurately assess the kinetic constants, which is especially important when designing new butyrylcholinesterase variants capable of full-cycle hydrolysis of organophosphorus compounds.
Heikin-Ashi Transformation and Vix Index data for Stock Market Index Prediction and It's Effects
Authors: Sharma Nishchal , Chauhan Chaman Singh
Published: February 2019

This paper performs a comprehensive analysis of Vix Index data with Heikin Ashi Transformation of stock index Neural Network Learning. It has been demonstrated that Heikin Ashi Transformation can improve the learning effect of Neural Network and the effect can also be filter out if volume weights are also considered. This paper introduces another improvement beside using volume-weighted data. Instead volatility index is used as an input and its effect for neural network learning process is analyzed.
Hemşirelerin Yaşlıya Tutumları ve Etkileyen Faktörler
Authors: PEHLİVAN Seda , VATANSEVER Nursel
Published: February 2019

Çalışma, hemşirelerin yaşlıya yönelik tutumlarının
ve etkileyen faktörlerin belirlenmesi amacıyla tanımlayıcı olarak yapıldı.
Araştırma, çalışmaya katılmayı kabul eden 217 hemşire ile yapıldı. Çalışmanın
verileri, araştırmacılar tarafından hazırlanan “Hemşire Bilgi Formu”, “UCLA
Yaşlı Tutum Ölçeği” ve “KOGAN Yaşlı Tutum Ölçeği” ile toplandı. Verilerin
değerlendirilmesinde, student t testi, ANOVA, Pearson korelasyon analizleri
yapıldı. Hemşirelerin yaş ortalamasının 33.79±7.05 yıl, çalışma sürelerinin
11.40±7.69 yıl olduğu belirlendi. Hemşirelerin %70.5’i evli, %83.9’unun
ailesinde en az bir yaşlı yakını olduğu ve %34.1’inin çalıştığı klinikte yatan
hastaların yarısından fazlasının yaşlı olduğunu ifade etti. Hemşirelerin yaşlı
yönelik tutumlarının olumlu olduğu, yaş ve çalışma yılı arttıkça yaşlıya
yönelik tutum puanının arttığı saptandı (p<0.05). Evli, çocuk sahibi olan,
yaşlı yakını olan, anne/babası vefat etmiş olan hemşirelerin yaşlı yönelik
tutum puan ortalamalarının daha yüksek olduğu ve özel birimlerde çalışanların
en düşük yaşlı tutum puan ortalamasına sahip olduğu belirlendi (p<0.05). Hemşirelerin
geriatri hemşireliği dersini alma durumunun yaşlı yönelik tutumunu etkilemediği
belirlendiğinden, toplumsal, kültürel ve bireysel değerlerin yaşlıya yönelik tutumu
etkilediği sonucuna varılmıştır.
Reproduktif Sistemde ADAMTS Genleri
Authors: KALEM Ziya , NAMLI KALEM Müberra , ŞİMŞİR Coşkun
Published: February 2019

Güncel genetik
çalışmalarından ele edilen bilgilere göre pek çok gen çeşitli üreme organ ve
dokularında hayati rol oynamaktadır. Fertilitenin tüm makro- ve
mikro-süreçlerinde yoğun araştırmalar devam etmesine ve system çözülmeye
çalışılmasına rağmen, üreme sistemi patofizyolojisi halen tüm bilinmezliğiyle
karşımızda durmaktadır.  Ekstrasellüler matriks
(ECM) hücreler için yapısal bir destek olmasının yanısıra hücrenin şekli,
davranışı, diferansiasyonu, proliferasyonu, gen expresyonu ve hayatiyetleri
üzerinde  belirleyici rolü olan  fonksiyonel bir dokudur. “A Disintegrin-like And Metalloproteinase
with Thrombospondin type-1 motif” (ADAMTS)
proteinleri, ECM yapılarının yıkımından sorumlu, vücutta birçok fizyolojik ve
patolojik  süreçte önemli rolleri olan
çinko bağımlı proteinazlardır. Bu
derlemenin amacı üremenin patofizyolojisinde ADAMTS‘lerin rolleri üzerine
yapılmış çalışmaları biraraya getirerek konuyla ilgili geniş bir perspektif
sunmaktır.
Attitudinal and Structural Determinants of Entrepreneurial Intentions of Women
Authors: Banning Kevin , Chinta Ravi
Published: February 2019

Entrepreneurial intentions have been shown to be a good predictor of entrepreneurial activity, and consequently have attracted the attention of many scholars and policy makers. Because entrepreneurial activity provides an economic engine for job growth, it is crucial to identify what drives entrepreneurial intentions. Extant literature has focused on such factors as the availability of capital, governmental support, individual networks, and culture. This study empirically investigates the expected linkage between attitudinal and structural factors and the intensity of intention to start a business for women entrepreneurs in the southeastern United States. Results from a survey of 1200 women intending to start a business in reveal that significant attitudinal and structural barriers remain for women entrepreneurs. The paper concludes with implications for women entrepreneurs, policy makers, and for future research.
Economic Transformation in Bangladesh and the Income Velocity of Broad Money: An Econometric Analysis
Authors: Khanom Ms. Sharmina
Published: February 2019

This study has undertaken an econometric analysis of economic transformation and income velocity of broad money. To find out the relevant determinants of income velocity of money this paper used time series data on year basis. This paper focus to discover the key determinants of the velocity of money in Bangladesh using the Augmented Dicky Fuller (ADF) unit root test to inspect the stationary, Engle-Granger residual-based cointegration approach to demonstrate the co-integrating association among variables. The main conclusions of this paper are: (i) relationship exists between the velocity of money and financial development. Other important variables that determine GDP growth show a negative relationship with the velocity of money but maintain a positive relationship with the deposit interest rate. Finally, this study concludes by giving some policy recommends for Bangladesh with respect to the velocity of broad money and the monetary policy.
Study of the dynamics of the working cell of the automatic mill of the pipe-rolling unit
Authors: Rakhmanov S.R. , Vyshinskyi V.T
Published: February 2019

Purpose. Determining the real spectrum and the level of dynamic loads would make it possible to develop recommendations for improving the TPA-350 automatic mill, with the aim of expanding its technological capabilities, improving the reliability of operation and durability.
Metodology. This work was carried out on the basis of the development of a mathematical model of dynamic processes in the mechanical system of an automatic TPA mill, where an attempt was made to identify the features of the functioning of a working stand with a rolled sleeve in the formulation of dynamic problems. Obviously, the proposed approach is more correct and convenient when studying complex dynamic phenomena in the elements of an automatic TPA mill.
Findings. The results of the study of the dynamics of the working stand of the automatic mill of the pipe-rolling unit (TPA) are given The basic parameters of the functioning of the working stand, such as the automatic mill TPA 350, are established, and a mathematical model of the basic problem of the dynamics of a mechanical system is developed. The differential equations of motion for the selected model of the working stand and the elastic elements of the bed retention mechanism on the support nodes of the automatic TPA mill have been compiled. The corresponding patterns of oscillations of the working stand were obtained. Some features of the functioning of the working stand are identified by the example of an automatic mill TPA 350. The dynamic parameters of the working stand of the mill, affecting the difference in the thickness of the rolled sleeves, are established.
Originality. The interrelation of the working stand dynamics with the operating conditions of an automatic TPA mill on the basis of a simplified mathematical model of dynamic processes is established. A mathematical model of the mechanical system of a working working stand of an automatic TPA mill has been compiled. In the most general form, the mechanical system of a working stand of a mill is described using differential equations describing the behavior of the selected design scheme of a system with two degrees of freedom.
Practical value. A scheme has been proposed for modernizing the working stand and the mechanism for holding the working stand of the TPA-350 automatic mill. IL. 4. Biblography: 8 titles.
Using Nonperforming Loan Ratios to Compute Loan Default Rates With Evidence From European Banking Sectors
Authors: Serwa Dobromił
Published: February 2019

This research is the first attempt to calibrate default rates of loan portfolios using raw data on nonperforming loans and some additional information on the maturity structure of the loan portfolios. We applied a simple model of loan quality, controlling for loan maturities and dynamics of loan supply. Results for nine national aggregate indices of nonperforming housing loans in the Czech Republic, Greece, Ireland, Hungary, Latvia, Poland, Portugal, Romania, and Spain revealed strong differences in the dynamics of calibrated default probabilities between countries. Calibrated default rates were correlated with macroeconomic factors, but the linkages depended on the markets investigated.
Financial Instability and Inequality Dynamics in the WAEMU
Authors: Thioune Thierno
Published: February 2019

This article assesses the effect of financial instability on income inequality and vice versa. The methodology used in this article is based on two approaches: theconstruction of the synthetic index of financial instability (SIFI) and the panel vector autoregressive (PVAR) approach. The results obtained help to explain that the disparity of income in a West African Economic and Monetary Union (WAEMU) country in each year negatively influences the stability of the financial sector the following year. Functions of impulse responses show that a shock to financial stability has a negative effect on itself and leads to a stable situation after seven periods. A rise in income inequality in WAEMU countries tends to mitigate financial instability at first, before boosting a higher level of instability. Following this increase, inequality will decline, but at a very slow pace.
Revisiting Herding Investment Behavior on the Zagreb Stock Exchange: A Quantile Regression Approach
Authors: Škrinjarić Tihana
Published: February 2019

Herding investment behavior on stock markets has consequences for practitioners, theorists, and policy makers. Thus, empirical research on this topic in the last couple of years has grown exponentially. However, there exist only a few papers dealing with herding behavior that consider the Croatian stock market. This study employs the quantile regression approach of estimating several herding investor behavior models of this market for the first time in the literature. Based upon daily data for the 37 most liquid stocks in the Zagreb Stock Exchange (ZSE) for the period September 22, 2014 to May 8, 2018, several model specifications are determined using quantile regression. Because the quantile regression approach deals with specific characteristics of financial data (stylized facts) better than the OLS method, more robust results can be achieved for evaluating if herding behavior is present in the Croatian market. The results indicate very weak to almost nonexistent evidence of herding behavior in the ZSE. Moreover, market volatility does not have any effect on herding behavior. Finally, the economic and political crisis (regarding concern Agrokor) in 2017 was controlled for in the model and the crisis was found insignificant. It seems that herding behavior does not need to be taken into account when tailoring investment strategies on the ZSE.
Elimination of pain syndrome in patients with advanced pancreatic head cancer
Authors: Gevorkyan T. G. , Feinstein I. A.
Published: February 2019

Pain syndrome, along with mechanical jaundice, is one of the most evident clinical manifestations of pancreatic cancer and is often a sign of tumor neglecting. Existing treatment options for chronic pain in cancer patients are diverse and include the various ways of impact on the different links of pathological pain: medicinal, endoscopic, surgical. With this pathology, drug therapy using analgesics, weak and strong opioids, is usually not effective enough. In such cases, preference is given to chemical neurolysis — denervation of the autonomic structures of the retroperitoneal space, carried out under the guidance of ultrasound or computed tomography. Conducting percutaneous neurolysis of the celiac plexus with the use of alcohol or phenol is prescribed upon insufficient effectiveness of pharmacotherapy. Surgical methods of anesthesia are used extremely rarely, as they considerably worsen the patient’s condition, without significantly affecting the quality of life or the prognosis. Thoracoscopic splanchnicectomy is considered a modern and effective method of endoscopic treatment of pain in unresectable pancreatic cancer, the conduction of which can significantly decrease the intensity of pain, reduce the number of narcotic analgesics and improve the quality of life of cancer patients. This minimally invasive intervention is the basis for the subsequent lifelong systemic drug therapy.
Halitosis syndrome in clinical practice
Authors: Gubergrits N. B. , Byelyayeva N. V. , Klochov A. Y. , Lukashevich G. M. , Rakhmetova V. S. , Yur’yeva A. V. , Yaroshenko L. A.
Published: February 2019

Definition of the medical term “halitosis” is presented in the article, historical aspects of its appearance are reviewed, probable prevalence of halitosis in the general population is indicated. Classification of halitosis with the allocation of its subtypes depending on the conditions of occurrence is given, the reasons for the development of true and false, physiological and pathological halitosis are analyzed. Various nosological items and pathological conditions are listed, the course of which may be accompanied by the appearance of bad breath. The influence of the emotional background on the occurrence of halitosis is described. The main substances, which metabolism is accompanied by the appearance of stomatodisodia, are named, the nature of unpleasant odors associated with the most common somatic diseases is indicated. The role of Helicobacter pylori, bacterial overgrowth and obesity syndrome in the development of halitosis is considered. The importance of a detailed collection of anamnesis and a thorough objective examination, as well as the exclusion of dental and otorhinolaryngological pathology in the implementation of a diagnostic search, were emphasized. The tactics of the doctor’s actions while treating patients with halitosis is outlined, the features of the intra-syndromic and nosological diagnostics are considered, the methods for performing the olfactory test, taking scrapings from the tonsils and the back of the tongue are described. The main directions of non-pharmacological and pharmacological treatment of halitosis are listed, hygiene of oral cavity and dentures, modification of the usual diet are emphasized, the appropriateness of timely application of combined antiseptic solutions and the possibility of systemic antibacterial therapy are stressed.