bluuebunny/crossref_metadata_2025 huggingface dataset:
NEW DATA ON TUMBLING FLOWER BEETLES (COLEOPTERA: MORDELLIDAE) OF THE FAUNA OF UKRAINE
Authors: Buialska N. P.
Published: September 2024

Introduction. Analysis of the published data indicates that further research to establish the taxonomic composition of tumbling flower beetles of the fauna of Ukraine is needed. The ecology of tumbling flower beetles including species that are part of the fauna of Ukraine has been little studied. The host plants of tumbling flower beetle larvae are the least known. The data on the distribution of tumbling flower beetles in Ukraine remain fragmentary.
Aim. The aim of the work is to analyze the distribution and trophic relationships of 23 species of tumbling flower beetles that were revealed during ecological and faunistic studies on the territory of Ukraine in the period 2015–2021.
Methods. Generally accepted research methods were used during the study. The observations of the feeding of tumbling flower beetles were carried out under natural conditions. Host plants of tumbling flower beetle larvae were revealed by examining herbaceous plants and dead wood during the beginning of the flight period of adults.
Main results. During ecological and faunistic studies 23 species of tumbling flower beetles were identified, of which 9 species were recorded for the first time in the Chernigov region, two species – in the Odesa one. The presence of Mordellistena episternalis Mulsant, 1856 and M. secreta Horák, 1983 in the fauna of Ukraine was confirmed. Host plants for imago are presented for 16 anthophilic species. Trophic relationships of chortobiont species at the larval stage with herbaceous plants of 8 species, which belong to 5 families, have been identified. The host plant (Jacobaea vulgaris Gaertn.) of the larvae of Mordellistena pseudopumila Ermisch, 1963 was indicated for the first time. The development of xylophilous species in the wood of three plant species was recorded. The results obtained are augmented with data from literature sources.
Conclusions. Thus, the data obtained clarify the taxonomic composition and distribution of tumbling flower beetles of the fauna of Ukraine. They include new data on the feeding of adults and larvae of tumbling flower beetles and can be used to develop measures for rational environmental management and conservation of biological diversity in Ukraine. Control of the development of the larvae of Mordellistena parvula (Gyllenhal, 1827) on wild plants can reduce the number of the said sunflower pest.
Developing Ideological Intelligence in Schools: Appreciation and Practice of Pancasila Values through Extracurricular Activities
Authors: Hariyanti Hariyanti , Permady Gigieh Cahya , Irayanto Irma , Kartasasmita Saepudin , Istianah Anif
Published: September 2024

The article's purpose is to describe the idea of ​​actualizing Pancasila values ​​through extracurricular activities to build students' ideological intelligence in school. Data was collected through literature studies using theories relevant to the research theme. In Indonesia, shared values ​​are expressed in Pancasila, which can unite society amidst differences in culture, race, language, religion and political beliefs. Pancasila, as a state ideology, provides orientation, insight, and normative guidelines in all areas of life. Ideological intelligence is needed to appreciate, internalize and apply Pancasila values ​​in life. Ideological intelligence through education is realized in Pancasila, and citizenship education (PPKn) is realized in schools. The revitalization of PPKn as ideological education can be realized in extracurricular activities under the coordination of PPKn teachers, with the advantages of: 1) It provides an ideological learning experience that is fun and easy to digest for students. 2) I am avoiding elements of indoctrination in learning. 3) The entire school community is involved in an open place because ideological intelligence cannot be developed through rhetoric and symbols.
Breme predpisov in standardizacije v sezoni 2024/2025
Authors: Kežmah Boštjan
Published: September 2024

Prispevek obravnava vpliv novih predpisov in sprememb standardov na področju informacijske varnosti, s poudarkom na standardu ISO/IEC 27001:2023 in prihajajočem slovenskem Zakonu o informacijski varnosti (ZInfV-1). Zakon bo bistveno razširil število zavezancev, kar bo zanje predstavljalo dodatne obremenitve pri zagotavljanju skladnosti s predpisi. Poudarek prispevka je na ključnih spremembah standarda ISO 27001, zlasti v prilogi A, kjer je število kontrol zmanjšano na 93, vendar so te postale zahtevnejše in bolj celovite. Med novimi kontrolami v praksi predstavljajo izziv obveščevalne informacije o grožnjah, informacijska varnost pri uporabi oblačnih storitev in pripravljenost IKT za neprekinjeno poslovanje zaradi nepopolnega razumevanja in izvajanja teh kontrol. Prihajajoče spremembe bodo od organizacij zahtevale večjo pozornost in prilagoditve v operativnih in strateških postopkih.
Identification of quantitative trait loci of pod dehiscence in a collection of soybean grown in the southeast of Kazakhstan
Authors: Doszhanova B. N. , Zatybekov A. K. , Didorenko S. V. , Suzuki T. , Yamashita Y. , Turuspekov Y.
Published: September 2024

Soybean [Glycine max (L.) Merr.] is one of the important crops that are constantly increasing their cultivation area in Kazakhstan. It is particularly significant in the southeastern regions of the country, which are currently predominant areas for cultivating this crop. One negative trait reducing yield in these dry areas is pod dehiscence (PD). Therefore, it is essential to understand the genetic control of PD to breed new cultivars with high yield potential. In this study, we evaluated 273 soybean accessions from diﬀerent regions of the world for PD resistance in the conditions of southeastern regions of Kazakhstan in 2019 and 2021. The field data for PD suggested that 12 accessions were susceptible to PD in both studied years, and 32 accessions, in one of the two studied years. The genotyping of the collection using a DNA marker for the Pdh1 gene, a major gene for PD, revealed that 244 accessions had the homozygous R (resistant) allele, 14 had the homozygous S (susceptible) allele, and 15 accessions showed heterozygosity. To identify additional quantitative trait loci (QTLs), we applied an association mapping study using a 6K SNP Illumina iSelect array. The results suggested that in addition to major QTL on chromosome 16, linked to the physical location of Pdh1, two minor QTLs were identified on chromosomes 10 and 13. Both minor QTLs for PD were associated with calmodulin-binding protein, which presumably plays an important role in regulating PD in dry areas. Thus, the current study provided additional insight into PD regulation in soybean. The identified QTLs for PD can be efficiently employed in breeding for high-yield soybean cultivars.
Exploitation of the genetic potential of Thinopyrum and Agropyron genera to protect wheat from diseases and environmental stresses
Authors: Plotnikova L. Ya. , Knaub V. V.
Published: September 2024

Common wheat is one of the most important food crops in the world. Grain harvests can be increased by reducing losses from diseases and environmental stresses. The tertiary gene pool, including Thinopyrum spp., is a valuable resource for increasing genetic diversity and wheat resistance to fungal diseases and abiotic stresses. Distant hybridization between wheat and Thinopyrum spp. began in the 1920s in Russia, and later continued in diﬀerent countries. The main results were obtained using the species Th. ponticum and Th. intermedium. Additionally, introgression material was created based on Th. elongatum, Th. bessarabicum, Th. junceiforme, Agropyron cristatum. The results of introgression for resistance to diseases (leaf, stem, and stripe rusts; powdery mildew; Fusarium head blight; and Septoria blotch) and abiotic stresses (drought, extreme temperatures, and salinity) to wheat was reviewed. Approaches to improving the agronomic properties of introgression breeding material (the use of irradiation, ph-mutants and compensating Robertsonian translocations) were described. The experience of long-term use in the world of a number of genes from the tertiary gene pool in protecting wheat from leaf and stem rust was observed. Th. ponticum is a nonhost for Puccinia triticina (Ptr) and P. graminis f. sp. tritici (Pgt) and suppresses the development of rust fungi on the plant surface. Wheat samples with the tall wheatgrass genes Lr19, Lr38, Sr24, Sr25 and Sr26 showed defence mechanisms similar to nonhosts resistance. Their influence led to disruption of the development of surface infection structures and fungal death when trying to penetrate the stomata (prehaustorial resistance or stomatal immunity). Obviously, a change in the chemical properties of fungal surface structures of races virulent to Lr19, Lr24, Sr24, Sr25, and Sr26 leads to a decrease in their adaptability to the environment. This possibly determined the durable resistance of cultivars to leaf and stem rusts in diﬀerent regions. Alien genes with a similar eﬀect are of interest for breeding cultivars with durable resistance to rust diseases and engineering crops with the help of molecular technologies.
Defining College Student Financial Literacy Utilizing the Delphi Method
Authors: Gatti Mary Taggart
Published: September 2024

Utilizing the Delphi method, the purpose of this study was to determine the most appropriate financial planning topics for the financial literacy of traditionally aged undergraduate college students. The Delphi method is a qualitative approach used to achieve convergence of opinion concerning real-world knowledge. At the end of the Delphi process, 38 specific topics reached consensus among experts that they were important for all college students to know. These 38 topics can also be grouped into nine larger themes: (a) budgeting, (b) credit, (c) insurance, (d) retirement/benefits, (e) investing, (f) debt management, (g) taxes, (h) banking, and (i) others. Reaching consensus on important topics provides colleges and universities with a road map of what topics they need to ensure that their students are learning. It also lays the foundation for the future development of a valid and reliable instrument to measure college student financial literacy.
Integrating Climate into Humanitarian and Peacebuilding Programming in Sub-Saharan Africa
Authors: Zaidan Mahdi
Published: September 2024

This report covers the emerging evidence from the integration of climate change concerns into peacebuilding and humanitarian programming. The review starts with an outline of the general effect of climate change on both peacebuilding and humanitarian work before delving into insights from a selection of programmes implemented in Sub-Saharan Africa that have a climate change component. The key lessons, opportunities and challenges of incorporating environmental and climate change into programmes are described throughout the review. Although there is some academic and grey literature on the intersection of climate change concerns with humanitarian and peacebuilding efforts, the evidence base is limited.
OVERVIEW OF THE LEVEL OF COMMUNITY KNOWLEDGE ABOUT FLOOD DISASTER MITIGATION IN VILLAGE X
Authors: Dwi Putri Berlian Widyanty , Muthmainnah
Published: September 2024

Introduction: Flooding is a condition where an area or plain is submerged by water due to an increase in the volume of water. Flood disaster cause various physical and mental health impacts and even property losses. This flood can be prevented by the community through flood disaster mitigation. Flood mitigation needs to be developed and improved through appropriate and efficient measures. This research has to describe the level of public knowledge about flood disaster mitigation in village x. 
Method: This research uses a descriptive research method, with a cross-sectional research design and a quantitative approach. The sample in this study was 86 respondents with a random sampling technique. The analysis used in this research is univariate analysis.
Results: the result of the study indicate that respondents 75,6% have a good level of knowledge. Because the community has enough to understand the importance of the surrounding environment, public knowledge of flood disaster mitigation is good because many people obtain information about flood disaster mitigation in media mass and electronic. 
Conclusion: the community has a good level of knowledge, and it is recommended to be able to increase knowledge about flood disaster mitigation.
On Properties of Karamata Slowly Varying Functions with Remainder and Their Applications
Authors: Imomov Azam Abdurakhimovich , Tukhtaev Erkin E. , Sztrik János
Published: September 2024

In this paper, we study the asymptotic properties of slowly varying functions of one real variable in the sense of Karamata. We establish analogs of fundamental theorems on uniform convergence and integral representation for slowly varying functions with remainder depending on the types of remainder. We also prove several important theorems on the asymptotic representation of integrals of Karamata functions. Under certain conditions, we observe a “narrowing” of classes of slowly varying functions concerning the types of remainder. At the end of the paper, we discuss the possibilities of application of slowly varying functions in the theory of stochastic branching systems. In particular, under the condition of the finiteness of the moment of the type Exlnx for the particle transformation intensity, it is established that the property of slow variation with remainder is implicitly present in the asymptotic structure of a non-critical Markov branching random system.
Micronutrients and Major Depression: A Mendelian Randomization Study
Authors: Carnegie Rebecca E , Zheng Jie , Borges Maria C , Jones Hannah J , Wade Kaitlin H , Sallis Hannah M , Lewis Sarah J , Evans David M , Revez Joana A , Evans Jonathan , Martin Richard M
Published: September 2024

Background: Various vitamins and minerals have been implicated in the aetiology of depression. Objective: To estimate the effects of micronutrient exposures on major depressive disorder (MDD) and recurrent depression (rMDD) using Mendelian randomization (MR). Methods: We undertook a comprehensive bidirectional MR study of multiple micronutrient exposures on MDD and rMDD. Summary statistics were obtained from the Psychiatric Genomics Consortium (PGC) genome wide association studies (GWASs) of MDD (cases = 116,209; controls = 314,566), and rMDD (cases=17,451; controls=62,482). Results: None of the micronutrients with available genetic instruments were strongly associated with MDD or rMDD using traditional MR methods. However, using methods to increase analytical power by accounting for genetically correlated variants (e.g. cIVW), highlighted five micronutrients with possible causal effects. Point estimates for rMDD were the largest magnitude, with three micronutrients suggestive of a protective effect: serum iron (ORcIVW 0.90 per SD increase; 95% CI 0.85- 0.95; p=0.0003); erythrocyte copper (ORcIVW 0.97; 95% CI 0.95- 0.99; p=0.0004); and 25(OH) vitamin D (ORcIVW 0.81; 0.66- 0.99; p=0.04). Apparent adverse effects of increased selenium on the risk of MDD (ORcIVW 1.03; 95% CI 1.02-1.05; p=0.0003) and rMDD (ORcIVW 1.08; 95% CI 1.00-1.08; p=0.06), and serum magnesium on rMDD (ORcIVW 1.21; 1.01- 1.44; p=0.04); were less consistent between methods and may be driven by pleiotropy. Conclusions: Our results suggest weak evidence for a protective effect of iron, copper and 25(OH)D on major depressive outcomes, with mixed evidence for selenium and magnesium. There was no evidence to support a causal effect of any other micronutrients on MDD or rMDD, although genetic instruments were lacking, with insufficient power to detect small but important effects. Future micronutrient supplementation trials should ensure ample statistical power given modest causal effect estimates, and consider potential risks of supplementation, as some micronutrient effect estimates suggested potential harm in excess.
Exploring Metaheuristic Optimized Machine Learning for Software Defect Detection on Natural Language and Classical Datasets
Authors: Petrovic Aleksandar , Jovanovic Luka , Bacanin Nebojsa , Antonijevic Milos , Savanovic Nikola , Zivkovic Miodrag , Milovanovic Marina , Gajic Vuk
Published: September 2024

Software is increasingly vital, with automated systems regulating critical functions. As development demands grow, manual code review becomes more challenging, often making testing more time-consuming than development. A promising approach to improving defect detection at the source code level is the use of artificial intelligence combined with natural language processing (NLP). Source code analysis, leveraging machine-readable instructions, is an effective method for enhancing defect detection and error prevention. This work explores source code analysis through NLP and machine learning, comparing classical and emerging error detection methods. To optimize classifier performance, metaheuristic optimizers are used, and a modified algorithm is introduced to meet the study’s specific needs. The proposed two-tier framework uses a convolutional neural network (CNN) in the first layer to handle large feature spaces, with AdaBoost and XGBoost classifiers in the second layer to improve error identification. Additional experiments using Term Frequency-Inverse Document Frequency (TF-IDF) encoding in the second layer demonstrate the framework’s versatility. Across five experiments with public datasets, the CNN achieved an accuracy of 0.768799. The second layer, using AdaBoost and XGBoost, further improved these results to 0.772166 and 0.771044, respectively. Applying NLP techniques yielded exceptional accuracies of 0.979781 and 0.983893 from the AdaBoost and XGBoost optimizers.
A Unified Semiconductor-Device-Physics-Based Ballistic Model for the Threshold Voltage of Modern Multiple-gate MOSFETS
Authors: Chiang Te-Kuang
Published: September 2024

Based on the minimum conduction band edge caused by the minimum channel potential resulting from the quasi-3D scaling theory and the 3D density of state (DOS) accompanied by the Fermi-Dirac distribution function on the source and drain sides, a unified semiconductor-device-physics-based ballistic model is developed for the threshold voltage of modern multiple-gate (MG) transistors, including FinFET, W-gate MOSFET, and Nanosheet (NS) MOSFET. It is shown that the thin silicon, thin gate oxide, and high work function will alleviate the ballistic effects and resist the threshold voltage degradation. Besides, as the device dimension is further reduced to give rise to the 2D/1D DOS, the lowest conduction band edge is hence increased to resist the threshold voltage degradation. The nanosheet MOSFET exhibits the largest threshold voltage among the three transistors due to the smallest minimum conduction band edge caused by the quasi-3D minimum channel potential. Compared to P-type MOSFET (P-FET), the N-FET shows more threshold voltage because the electron has a more effective mass than the hole
Assessment from Multilevel Mixed-Effects Structural Equation Modelling into Urban Resilience
Authors: Hu Chich-Ping
Published: September 2024

The resilience of towns and cities refers to their ability to adapt and recover when confronted with pressures or challenges. This study employs ten variables as indicators to assess the resilience of urban areas by analyzing official data and constructing a multilevel mixed-effects structural equation model. The empirical findings demonstrate that enhancing resilience significantly influ-ences urban service functions, such as strengthening healthcare systems, stabilizing the real estate market, and addressing socio-economic challenges. Specifically, factors such as healthcare re-sources, housing demand, population structure, and social security exhibit varying levels of resil-ience, which profoundly impact the spatial distribution of these factors and socio-economic de-velopment. Disparities in healthcare resource allocation, demographic aging trends, and shifts in the housing market closely correlate with resilience levels in different regions. Additionally, the study emphasizes that improving resilience not only boosts the reliability and security of urban services but also ensures that communities receive necessary support and protection during times of adversity. Consequently, policymakers should recognize the pivotal role of urban resilience in resource allocation and social equity, devising corresponding strategies to enhance the resilience of these areas.
A Novel Spectral Density Function Validation for Bessel’s Equation in L-N Form
Authors: Mandelkern Jeremy
Published: September 2024

In the 2014 paper by C. Fulton, D. Pearson, and S. Pruess [7], a new characterization of the spectral density function is given for a Sturm-Liouville equation. These authors provide spectral theory showing that the Appell system, a companion linear system of ordinary differential equations, can be utilized to obtain a spectral density function. Though this new method is both elegant for its simplicity and fully viable (as is shown in this work), it has largely been ignored in the literature since its discovery. To motivate greater attention towards this new theory, and its potential applications, work is given here by this author demonstrating a nontrivial example of this new spectral method being applied towards the Bessel Equation in its Liouville-Normal (L-N) form. Validations of results obtained in this paper are also given, showing full agreement with the classical results obtained by E.C. Titchmarsh in [11].
Hierarchical Analysis of Miombo Woodland Spatial Dynamics in Lualaba Province (DR Congo), 1990-2024: Integrating Remote Sensing and Landscape Ecology Techniques
Authors: Useni Sikuzani Yannick , Mpanda Mukenza Médard , Kikuni Tchowa John , Kabamb Kanyimb Delphin , Malaisse François , Bogaert Jan
Published: September 2024

Lualaba Province, located in the southeastern Democratic Republic of the Congo, consists of five territories with varied dominant land uses: agriculture (Dilolo, Kapanga, and Musumba in the west) and mining (Mutshatsha and Lubudi in the east). The province also includes protected areas with significant governance challenges. The unique miombo woodlands of Lualaba are threatened by deforestation, posing risks to biodiversity and local livelihoods that depend on these woodlands for agriculture and forestry. To quantify the spatio-temporal dynamics of Lualaba's landscape, we utilized Landsat images from 1990 to 2024, supported by a Random Forest Classifier. Landscape metrics were calculated at multiple hierarchical levels: province, territory, and protected areas. Our provincial-level analysis revealed a pronounced deforestation trend, with miombo woodland cover declining from 62,90 % to less than 25 % over the 34-year period. This trend was characterized by the fragmentation and dissection of woodland patches and a decline in remaining woodland fragments, due to their ongoing replacement by savannas, agriculture, and urbanization. The average distance between miombo woodland patches increased significantly, indicating heightened fragmentation and spatial isolation. Agricultural areas such as Sandoa and Kapanga were particularly vulnerable to deforestation. On the other hand, the miombo forest cover in the mining areas is still representative, with over 30% of the landscape covered. Notably, the reduction in woodland cover within protected areas was substantial, with significant losses observed across both agricultural and mining territories. The loss of miombo woodland cover in Lualaba and its territories was accompanied by an increase in landscape patch diversity, as indicated by the Shannon diversity index, suggesting a shift to more heterogeneous landscapes. These findings underscore a complex deforestation pattern, highlighting the intense local impact on miombo woodland cover loss. Urgent action is needed to implement land conservation policies, promote sustainable agricultural practices, strengthen miombo woodland regulation enforcement, and actively support protected areas. Involvement from both local and international stakeholders is imperative to preserve the ecological richness and functionality of Lualaba Province's miombo woodland ecosystems.
In Silico Development of SARS-CoV-2 Non-covalent Mpro Inhibitors: A Review
Authors: Alagawani Islam , Wang Feng
Published: September 2024

Coronaviruses (CoVs) have recently emerged as significant causes of respiratory disease outbreaks. The novel coronavirus pneumonia of 2019, known as COVID-19, are highly infectious and triggered by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Understanding virus-host interactions and molecular targets in host cell death signalling is crucial for treatment development. Small natural compounds like celastrol and curcumin, acting as proteasome inhibitors, can potentially modify NF-κB signalling for treating SARS-CoV-2 infections. Various natural constituents, including alkaloids, flavonoids, terpenoids, diarylheptanoids, and anthraquinones, inhibit viral infection, progression, and amplification of coronaviruses. Derived from medicinal herbs, these compounds possess anti-inflammatory and antiviral properties, impacting the viral life cycle, including entry, replication, assembly, and release of COVID-19 virions. This review focuses on the development of small molecules of non-covalent inhibitors targeting the Main Protease (Mpro, also called 3CLpro) enzyme of SARS-CoV-2. It highlights the design using molecular dynamics (MD) studies and computational methods for further improvements in Mpro inhibitor design. The in-silico approach, which is pivotal in this process, provides an accelerated virtual avenue for exploring and developing potential inhibitors, representing the latest advancements in drug design.
Implication of Public-Private Partnerships in Construction
Authors: Zhang Wei
Published: September 2024

Public-Private Partnerships (P3 or PPPs) have been utilized and studied more frequently over the past couple of decades for both infrastructure projects and building development projects. Based upon the records of the outcomes of these projects there is a plethora of data that demonstrates the benefits and challenges that this delivery method poses. As the name suggests, these partnerships allow for public goals to become realized while also providing opportunities for the private sector to gain business success. These two often divergent interests are finding mutual benefit but the process of compromises also comes with some disadvantages that should be understood in order to make decision of whether the risk/reward equation works for all stakeholders. In particular, this paper will focus on how PPPs affect the construction aspects of projects and will assert how to understand the risks and evaluate the benefits from a construction perspective.
Physicochemical Quality and Application Potential of Pereskia spp. Flours in Pasta Products
Authors: Berto Ismaiara Rodrigues , dos Santos Moreira Inacia , Rocha Thayse Cavalcante da , Tejo Cavalcanti Mônica , Pereira Lima Renato , Valentim Moura Henrique , Rodrigues Cavalcante Iara Tamires , Lins Cassimiro Carlos Alberto , Araújo Jucilene Silva , Rabelo da Costa Batista Fabiane , Pereira Emmanuel Moreira
Published: September 2024

This study investigates the use of flours derived from the leaves of Pereskia aculeata and Pereskia grandifolia, commonly known as ora-pro-nóbis, in pasta products. The motivation stems from the search for nutritious and affordable dietary alternatives that promote food security. The objective is to produce flours from the leaves of these species through convection drying and to assess their physicochemical quality and potential application in spaghetti-type pasta. The leaves were dehydrated and processed into flour, which was then incorporated into pasta formulations in varying concentrations from 1% to 7%. The resulting samples underwent physicochemical, antioxidant, toxicity, and mineral composition analyses. Significant differences were observed between the flours of P. aculeata and P. grandifolia in terms of protein, lipid, carbohydrate, and bioactive compound content. P. grandifolia was noted for its higher protein and mineral content, while P. aculeata exhibited superior antioxidant activity. The pasta enriched with these flours demonstrated improvements in nutrient content and changes in colorimetric properties. The study concludes that ora-pro-nóbis flours possess high nutritional value and are viable for application in pasta products, contributing to a healthier and more diversified diet without compromising the sensory characteristics of the products.
Exploring the Efficacy of Alpha-Lipoic Acid in Comorbid Osteoarthritis and Type 2 Diabetes Mellitus
Authors: Halabitska Iryna , Oksenych Valentyn , Kamyshnyi Oleksandr
Published: September 2024

The comorbidity of osteoarthritis and type 2 diabetes mellitus represents a complex clinical challenge and complicates patient management due to the interplay of overlapping pathophysiological mechanisms. The research aimed to analyze the exacerbation of clinical symptoms and biochemical markers in patients with osteoarthritis and type 2 diabetes mellitus compared to those with osteoarthritis. We utilized various assessment methods to measure the patient cohorts' inflammation, oxidative stress, and glycemic control. The study also involved the administration of alpha-lipoic acid to patients with comorbid osteoarthritis and type 2 diabetes mellitus and monitored its effects on joint function, inflammatory markers, oxidative stress levels, and glycemic control. Our findings revealed that the presence of type 2 diabetes mellitus significantly intensified osteoarthritis symptoms and altered biochemical markers, including increased inflammation, elevated oxidative stress, and disrupted immunological balance. The treatment with alpha-lipoic acid resulted in improved joint function, reduced inflammation and oxidative stress levels, and better glycemic control. Additionally, it was identified several potential predictors for developing osteoarthritis and type 2 diabetes mellitus comorbidity. The results underscore the detrimental impact of type 2 diabetes mellitus on osteoarthritis and highlight the beneficial effects of alpha-lipoic acid in alleviating some of the adverse consequences associated with this comorbidity. Nonetheless, further research is necessary to comprehensively evaluate the therapeutic efficacy of alpha-lipoic acid and its long-term effects on managing comorbidity of osteoarthritis and type 2 diabetes mellitus.
Healthcare Resource Utilization (HCRU) and Direct Medical Costs Associated with Long COVID or Post-COVID Conditions: Findings from a Literature Review
Authors: Łukomska Elżbieta , Kloc Krzysztof , Kowalska Malwina , Matjaszek Aleksandra , Joshi Keya , Scholz Stefan , Van de Velde Nicolas , Beck Ekkehard
Published: September 2024

Approximately 10–20% of individuals suffering from COVID-19 develop prolonged symptoms known as long COVID or post-COVID condition (LC). This review aimed to assess healthcare resource use (HCRU) and healthcare costs associated with LC. Because LC is not clearly defined and often remains undiagnosed, studies reporting on long-term follow-up of individuals with a COVID-19 diagnosis were also included. Among the 41 publications included, 36 reported on HCRU and 16 on costs. Individuals with LC had significantly elevated HCRU and healthcare cost vs controls without a COVID-19 diagnosis over ≥15 months, with a 7.6%–13.1% increase in total healthcare costs per person per month as assessed by difference-in-difference analysis. Among studies that did not specifically refer to LC, having a COVID-19 diagnosis was associated with a significant 4–10% increase in long-term total HCRU over 6–8 months and a 1.3- to 2.9-fold relative increase in total healthcare costs over 6 months. Due to the heterogeneity of included studies, high-quality evidence is needed to better understand the economic burden of LC. In the absence of effective treatments, prioritizing prevention of acute COVID-19, e.g., through vaccination, may be crucial for preventing LC and the associated long-term HCRU and medical spending.
Adaptations in Vocational Guidance: Experience from the Colombian Amazon
Authors: Torres-Reyes Aura M.
Published: September 2024

As we move into late postmodernity, the instruments and processes proposed require research and development processes that allow them to remain in force within current technological mediations and trends. In this context, the instruments that facilitate vocational guidance processes are included. Therefore, this innovation experience arises as a response to the needs present in the Colombian context, based on two objectives: To reduce the number of items in the CHASIDE vocational orientation test, 2) To validate the resulting test. A longitudinal study with a quantitative approach was carried out, with a convenience sampling in three Colombian municipalities during 2019-2023. Quantitative statistical analysis techniques, data were analyzed including statistics of mean, variance, Pearson's correlation coefficient, hypothetical difference of means, degrees of freedom, t-statistic, P(t) and critical value of t (one tail and two tails), and others.  Additionally, internal consistency was checked using Cronbach's Alpha. Managing to reduce the test from 98 items to 35 items, preserving its two dimensions (Aptitudes and Interests), with a simpler structure, which responds to a Multifactorial Profile (PM), its validation confirmed the new structure, that established 7 factors for the dimension of aptitudes, constituted by 27 items and 3 factors for the Interests dimension with 8 items. In conclusion, social changes are reflected in factor structures and their groupings within professions, leaving the unifactorial proposed by Holland in the RIASEC, to give way to interactions within aptitudes and interests. Aptitudes being more stable than interests over time.
Fostering Intellectual Competence through Dialogic Learning in Islamic Boarding Schools
Authors: Fitriyanti Windy Ana , Haryanto Budi
Published: September 2024

This qualitative case study investigates the development of intellectual competence through dialogic learning at an Islamic boarding school. Employing participatory observation, the study explores the process of fostering intellectual competence through discussions within and outside formal learning activities, encouraging critical thinking towards diverse viewpoints, promoting confident expression grounded in literature, and active participation in scientific competitions. Results demonstrate that dialogic learning enhances students' critical thinking skills and encourages active engagement in scholarly pursuits, both locally and nationally. This research underscores the significance of dialogic pedagogy in nurturing intellectual competence within Islamic educational contexts, offering implications for fostering critical thinking and scholarly engagement in diverse educational settings.
Highlights :

Dialogic learning fosters critical thinking: Encouraging discussions outside formal activities cultivates a critical attitude towards diverse opinions.
Confidence in expression through literature: Instilling the courage to express opinions grounded in literature enhances intellectual competence.
Active participation in scientific competitions: Engagement in local and national competitions promotes scholarly pursuits and intellectual growth.

Keywords: Dialogic learning, Intellectual competence, Islamic boarding schools, Critical thinking, Scholarly engagement
Village Information System (SID) Effectiveness in Improving Village Administrative Services
Authors: Novianti Rosita Dwi , Agustina Isna Fitria
Published: September 2024

This research investigates the effectiveness of the Village Information System (SID) in improving public services in Sekardangan Village, focusing on the period of 2020-2022. The descriptive qualitative method is employed, utilizing primary and secondary qualitative data sources, including library research and interviews with the village head and operators. Results reveal that Sekardangan Village provides effective, fast, precise, and efficient services. However, the web-based SID has not been fully effective due to challenges faced by elderly residents with limited socialization from local government. This study contributes to the understanding of smart governance and the role of information systems in enhancing village administration services.
Highlight :

The study analyzes the effectiveness of the Village Information System (SID) in improving public services in Sekardangan Village, focusing on the period of 2020-2022.
Qualitative data sources, including library research and interviews with the village head and operators, were utilized to assess the effectiveness of the SID.
The results indicate that while Sekardangan Village provides effective, fast, precise, and efficient services, the web-based SID has not been fully effective due to challenges faced by elderly residents with limited socialization from the local government.

Keywords: Effectiveness, Village Information System, Public Service, Sekardangan Village, Qualitative Method
Impact of Investment, Funding, and Dividend Policies on Food & Beverage Firms' Valuation: IDX 2018-2021
Authors: Mahmudah Siti Miftakhurrohmah , Setiyono Wisnu Panggah
Published: September 2024

This study examines the impact of investment decisions, funding choices, and dividend policies on firm value in the Food and Beverage sector. Analyzing data from 14 IDX-listed companies over 2018-2021, findings indicate significant positive effects of investment and funding decisions on firm value, while dividend policy's influence is negative and insignificant. Together, these factors explain 75.3% of firm value variation, highlighting the pivotal role of strategic financial decisions in shaping company worth and suggesting managerial implications.
Highlight :

Strategic Financial Decisions: Investment and funding choices significantly impact firm value.
Dividend Policy: Despite being insignificant, dividend policy's effect on firm value is negative.
Sector-specific Analysis: Findings offer insights into financial dynamics within the Food and Beverage industry.

Keywords: Investment, Funding, Dividend Policy, Firm Value, Food & Beverage
Uncovering Barriers to Rural Development to Empower Communities in Indonesia
Authors: Novitasari Wulan , Rodiyah Isnaini
Published: September 2024

This research analyzes the role of the Village Community Empowerment Institution (LPMD) in the development of Watesnegoro village, Ngoro sub-district, Mojokerto district. Using a descriptive qualitative approach, data were collected from the village head, LPMD head, village secretary, treasurer, and planning officer through observation, interviews, and documentation. The study finds that while LPMD efforts in socialization, training, and community skill improvement are positive, overall effectiveness is limited by low community participation and inadequate human resources. Enhancing community involvement and human resource quality is essential for the success of LPMD programs and village economic development.
Highlights:

LPMD's Impact Assessment: Vital for Watesnegoro Village Development.
Limited Engagement: Hinders LPMD Programs and Economic Growth.
Skill Enhancement: Key to Effective LPMD and Community Empowerment.

Keywords: LPMD, Village Development, Community Empowerment, Mojokerto District, Qualitative Analysis
Uncovering Stunting Prevention through the Important Role of Posyandu Cadres
Authors: Anisyah Dewi , Fitria Agustina Isna
Published: September 2024

This study analyzes the role of posyandu cadres in preventing stunting in Cangkring Village, Malang, Beji District, Pasuruan Regency, using a descriptive qualitative approach. Data were gathered through interviews, observation, and documentation from village heads, posyandu cadres, midwives, and mothers of toddlers. Utilizing Lawrence Green's framework, the findings reveal that stunting prevention is hindered by limited parental knowledge (Predisposing Factors), inadequate health facilities (Enabling Factors), and low community awareness (Reinforcing Factors). The research highlights the need for better education, improved facilities, and stronger community and governmental support to enhance posyandu effectiveness in stunting prevention.
Highlights:
1. Knowledge Gap: Parental knowledge about stunting is insufficient.2. Infrastructure: Health facilities are inadequate and poorly maintained.3. Community Support: Low public awareness reduces posyandu effectiveness.
Keywords: Posyandu cadres, stunting prevention, rural health, qualitative research, community health
Международно-Правовые Аспекты Становления И Развития Проекта «Один Пояс, Один Путь»
Authors: Шавкат угли Аъзамхужаев Умидхон
Published: September 2024

Транспорт и транспортные коридоры имеют архиважное значение для обеспечения государственного суверенитета и независимости стран, в том числе, Республики Узбекистан.
Современная внутренняя и внешняя политика Нового Узбекистана направлена в том числе, на обеспечение транспортной интеграции страны в существующие и перспективные транспортные коридоры. Одним из таких перспективных транспортных коридоров является транспортная сеть в рамках проекта Экономический пояс Шелкового пути – стратегии Один пояс, один путь.
Китайская Народная Республика (КНР) в течении последних почти 20 лет как в рамках двусторонних, так и многосторонних связей активно продвигает различные проекты транспортно-коммуникационных коридоров, экономического сотрудничества, кооперации и интеграции. На сегодня, китайская инициатива Экономического пояса Шелкового пути[1] в рамках стратегии Один пояс, один путь – одна из самых обсуждаемых тем среди международников.
Frequency Of Cyp3a5 (A6986g) Gene Polymorphism In Patients With BA, COPD, And ACO
Authors: Raufov A.A.,  , FayzullaevaN.Ya.  , Ruzibakieva M.R.
Published: September 2024

Asthma and COPD are the most common chronic respiratory diseases, each with a specific pathophysiology. Usually, asthma is characterized by chronic inflammation of the airways with reversible symptoms, while COPD is characterized by persistent respiratory changes in the bronchopulmonary system. However, patients can sometimes have clinical features of both diseases, and this condition is called the asthma-COPD overlap (ACO) recommended by the joint guidelines of GINA (Global Strategy for the Management and Prevention of Asthma) and GOLD (Global Initiative on Chronic Obstructive Pulmonary Disease). According to this guide, ACOis characterized by "permanent airflow limitation with some features of asthma and COPD."
Impact of Short-term Patient Education Intervention on the Teaching Skills of Physical Therapy Students: a Randomized Controlled Trial
Authors: GRBAVAC Vedrana , NALETILIĆ Mladenka , ŠIMIĆ Josip
Published: September 2024

Background: Patient education is an important aspect of physiotherapy. Effective education is based on quality communication and understanding of patients' needs. For a successful practice, it is necessary to recognize the factors that affect the ability to teach the patient and prepare new physiotherapists for this task. The research aims to determine the effect of training on the self-efficacy and skills of physiotherapy students in patient education.
Methods: Students in the final year of physiotherapy were randomized into an intervention group (52 students) and a control group (51 students). The intervention group participated in 2.5 hours of lectures, discussions, simulated exercises with colleagues, and video examples of patient education. The control group had subsequent training. All students performed a self-assessment of their teaching abilities. Patient education was assessed by a blinded evaluator using the Objective Structured Clinical Examination from an audio-recorded simulated clinical practice task.
Results: The results show no differences in demographic variables, while a significant improvement was achieved for the intervention group after the training. The intervention group before the experiment did not perform differently than the control group on self-efficacy items (p>.05), but they did perform significantly better than the control group after the experiment (p<.001). The intervention group showed better results than the control group in almost all observed fields.
Conclusion: These findings suggest that the intervention positively increased the educational skills of physiotherapy students.
Non-contact concentration measurement of aqueous ethylene glycol solutions
Authors: Iwasaki Kazuma , Fujii Sho , Tanabe Tadao
Published: September 2024

To evaluate the concentration dependence of THz spectra, THz time-domain spectroscopy (THz-TDS) was used to measure the transmittance of aqueous solution samples of ethylene glycol in the frequency region below 0.4 THz at room temperature, and the spectrum was analyzed in the region below 0.2 THz, where water absorption is small. The results showed that the interference spectral shape based on the dielectric constant change changed when the liquid concentration of the ethylene glycol sample was varied. Peak separation was performed for the peaks in the obtained spectra, and a comparison of the change in peak position with concentration showed a shift in the peak at 0.17 THz. This result indicates the possibility of non-contact concentration measurement using terahertz waves.
Impact of Desmopressin ON HemaToma EXPANsion in Patients Presenting to the Emergency Department on Antiplatelet Therapy: DON'T EXPAND Study
Authors: Rech Megan A , Brown Caitlin S , Slocum Giles W , Gilbert Brian W , Aggarwal Deep , Ayad Michael , Delibert Samantha , Flack Tara , George Benjamin P , Guerrero Luis , Howington Gavin T , Koul Uttara , Laub Jessica , Malik Atul , Maynard Kaylee , Naylor Ryan M , Newell Joshua S , Panos Nicholas G , Ray Lance , Dee Elizabeth , Sarangarm Preeyaporn , Sheldrake Amy K , Shogren Sophie , Treu Ciarra N , Vantine Paul , Woolum Jordan A , Faine Brett A
Published: September 2024

Introduction: Current guidelines state the effectiveness of desmopressin to reduce hematoma expansion in antiplatelet-related intracerebral hemorrhage (ICH) is uncertain. This study sought to determine if desmopressin decreased hematoma expansion in ICH patients on antiplatelet agents.
Methods: We conducted a multi-center, retrospective propensity-matched cohort study at 11 US emergency departments (ED) that participate in EMPHARM-NET. Adult patients ≥18 years with a primary diagnosis of spontaneous ICH on antiplatelets prior to admission from January 1, 2017 through May 1, 2021 were included. The primary endpoint was good or excellent hemostatic efficacy within the first 24 hours following ICH between patients that did and did not receive desmopressin. Brain imaging was reviewed using 3D-Slicer by blinded expert physicians.
Results: Overall, 1408 patients were evaluated for inclusion. A total of 324 patients were included, of which 13.8% (n=45) received desmopressin and 86.1% (n=279) did not. After propensity matching, 35 patients receive desmopressin compared to 140 controls. Baseline hematoma volume (27.6 mL vs. 2.1 mL) and was significantly higher in the desmopressin group. The primary endpoint of good or excellent hemostatic efficacy was similar between groups (74.3% desmopressin group vs. 85% control group, -10.7% [-28.1% to 6.7%]). There was no difference in secondary outcomes.
Conclusion: In this multicenter cohort, patients receiving desmopressin had higher baseline intraparenchymal hematoma volume, and did not appear to result in improved hemostatic efficacy relative to the control group. These results suggest against routine administration of desmopressin for antiplatelet-related ICH, though future study in a randomized trial design is necessary.