bluuebunny/crossref_metadata_2025 huggingface dataset:
Hemodynamic instability following intravenous dexmedetomidine infusion for sedation under brachial plexus block: Two case reports
Authors: Kim Ye Sull , Lee Chanhong , Oh Jeongmin , Nam Seonhwa , Doo A Ram
Published: October 2023

Rehabilitation of lower limb amputation in developing countries is quite challenging. Though there are basic to highly advanced prostheses available in India, the set-up is still facing difficulties in developing countries. Prosthetic management is difficult due to lack of availability of prostheses and reduced affordability among low income populations. In this review we highlighted the lower limb amputation and prosthetic rehabilitation status in India. Currently, India is advancing well in the rehabilitation field, but further studies are required to provide more evidence and recommendation.
Diagonal-Schur complements of Nekrasov matrices
Authors: Wang Shiyun , Li Qi , Sun Xu , Lyu Zhenhua
Published: October 2023

The Schur and diagonal-Schur complements are important tools in many fields. It was revealed that the diagonal-Schur complements of Nekrasov matrices with respect to the index set $\{1\}$ are Nekrasov matrices by Cvetkovic and Nedovic  [Appl. Math. Comput., 208:225-230, 2009]. In this paper, we prove that the diagonal-Schur complements of Nekrasov matrices with respect to any index set are Nekrasov matrices. Similar results hold for $\Sigma$-Nekrasov matrices. We also present some results on Nekrasov diagonally dominant degrees. Numerical examples are given to verify the correctness of the results.
‘Family doesn’t have to be mom and dad’: an exploration of the meaning of family for care-experienced young people
Authors: Rees Alyson , Roberts Louise , Taussig Heather
Published: October 2023

Young people who experience out-of-home care have typically encountered difficult and/or disrupted family relationships. This article reports on a survey undertaken in the US with 215 young adults (aged 18–22) who experienced out-of-home care starting in pre-adolescence. The article examines responses to an open-ended interview question, ‘How do you define family?’ The analysis highlighted that few young people define family as confined to blood relations. More commonly, young people adopted more flexible definitions, prioritising the ‘doing’ and reflecting on their conceptions of family; attempting to ‘do family’ differently from what they had experienced was also evident. The findings encourage consideration of the utility of family as an important concept for child welfare practice, as positive and flexible understandings of family were imbued with a sense of agency, identity, belonging and overall wellbeing.
Derivational Affixes as Roots Across Categories
Authors: Simonović Marko
Published: October 2023

Abstract: Several recent accounts (Lowenstamm 2014; Nevins 2015; Creemers, Don, and Fenger 2017) couched in the framework of Distributed Morphology (Halle and Marantz 1993, 1994) argue for extending the separation between roots and categorial heads to derivational affixes. Such approaches offer a straightforward account of affixes that surface under different categorial embeddings (e.g., - ant , both in the noun defendant and in the adjective defiant ) by viewing these affixes as roots. In this article, the affixes-as-roots approach is applied to Slovenian affixes. An account is proposed of the variable prosodic behavior of Slovenian derivational affixes, which behave as either stress-attracting or stress-neutral. It is shown that Slovenian derivational affixes have no lexical stress and all their prosodic effects follow from the structures in which they occur. Specifically, stress-attracting behavior is a result of the fact that sequences of roots with no intermediate functional structure (the so-called radical cores) are spelled out to phonology without any prosodic specification. Phonology then assigns the default final prosody to such sequences, creating the illusion of accented derivational affixes. The proposed account is applied to two affixes, - av and - ov , which occur across categorial embeddings (nominal, verbal, adjectival).
The Numerals Dva, Tri, Četyre in the Novgorod Birch Bark Letters: A Diachronic Perspective
Authors: Slobodchikoff Tatyana
Published: October 2023

Abstract: This article investigates the emergence of the cardinal numerals dva 'two', tri 'three', and četyre 'four' in nominal phrases in the Novgorod dialect during the 11th–15th centuries. An innovative approach presented here brings together three productive lines of inquiry—corpus analysis, historical linguistics, and diachronic generative syntax. A corpus analysis was conducted to identify 301 tokens of numeral-containing NPs and to trace the patterns of their diachronic development. The cardinal numerals 2, 3, 4 are shown to evolve from the adjectival "number" words through the process of grammaticalization, more specifically, numeralization. After the loss of dual number, the lower adjectival "number" words for 2, 3, and 4 turned into the cardinal numerals, as their lexically encoded numerosity became functionally encoded countability. The diachrony of the cardinal numerals in the Old Novgorod dialect has shown that the cognitive concepts of cardinality, individuality, and countability are inextricably connected. These concepts are grammatically encoded and subject to diachronic change. This study has demonstrated that a change in grammatical number (loss of the dual) led to the restructuring of countability and the rise of cardinal numerals.
Wolbachia endosymbionts manipulate the self-renewal and differentiation of germline stem cells to reinforce fertility of their fruit fly host
Authors: Russell Shelbi L. , Castillo Jennie Ruelas , Sullivan William T.
Published: October 2023

The alphaproteobacterium Wolbachia pipientis infects arthropod and nematode species worldwide, making it a key target for host biological control. Wolbachia-driven host reproductive manipulations, such as cytoplasmic incompatibility (CI), are credited for catapulting these intracellular bacteria to high frequencies in host populations. Positive, perhaps mutualistic, reproductive manipulations also increase infection frequencies, but are not well understood. Here, we identify molecular and cellular mechanisms by which Wolbachia influences the molecularly distinct processes of germline stem cell (GSC) self-renewal and differentiation. We demonstrate that wMel infection rescues the fertility of flies lacking the translational regulator mei-P26 and is sufficient to sustain infertile homozygous mei-P26-knockdown stocks indefinitely. Cytology revealed that wMel mitigates the impact of mei-P26 loss through restoring proper pMad, Bam, Sxl, and Orb expression. In Oregon R files with wild-type fertility, wMel infection elevates lifetime egg hatch rates. Exploring these phenotypes through dual-RNAseq quantification of eukaryotic and bacterial transcripts revealed that wMel infection rescues and offsets many gene expression changes induced by mei-P26 loss at the mRNA level. Overall, we show that wMel infection beneficially reinforces host fertility at mRNA, protein, and phenotypic levels, and these mechanisms may promote the emergence of mutualism and the breakdown of host reproductive manipulations.
Eggs of the mosquito Aedes aegypti survive desiccation by rewiring their polyamine and lipid metabolism
Authors: Prasad Anjana , Sreedharan Sreesa , Bakthavachalu Baskar , Laxman Sunil
Published: October 2023

Upon water loss, some organisms pause their life cycles and escape death. While widespread in microbes, this is less common in animals. Aedes mosquitoes are vectors for viral diseases. Aedes eggs can survive dry environments, but molecular and cellular principles enabling egg survival through desiccation remain unknown. In this report, we find that Aedes aegypti eggs, in contrast to Anopheles stephensi, survive desiccation by acquiring desiccation tolerance at a late developmental stage. We uncover unique proteome and metabolic state changes in Aedes embryos during desiccation that reflect reduced central carbon metabolism, rewiring towards polyamine production, and enhanced lipid utilisation for energy and polyamine synthesis. Using inhibitors targeting these processes in blood-fed mosquitoes that lay eggs, we infer a two-step process of desiccation tolerance in Aedes eggs. The metabolic rewiring towards lipid breakdown and dependent polyamine accumulation confers resistance to desiccation. Furthermore, rapid lipid breakdown is required to fuel energetic requirements upon water reentry to enable larval hatching and survival upon rehydration. This study is fundamental to understanding Aedes embryo survival and in controlling the spread of these mosquitoes.
Causes and consequences of fever in Amazonian pregnant women: A large retrospective study from French Guiana
Authors: Hcini Najeh , Lambert Véronique , Picone Olivier , Carod Jean-Francois , Mathieu Mérédith , Cousin Romane , Akli Ferroudja , Carles Gabriel , Basurko Célia , Pomar Léo , Epelboin Loïc , Nacher Mathieu
Published: October 2023

Objective

The aim of this study was to describe different causes and consequences of fever during pregnancy in Western French Guiana and along the Maroni River.

Study design

A retrospective single-center study including all patients with a history of documented fever ≥ 38°C during pregnancy at the West French Guiana Hospital for 9 years. Postpartum fever and nosocomial infections were excluded. We focused on medical history and on clinical and biological findings. Causes were characterized as confirmed or uncertain and then classified as preventable or non-preventable.

Results

A total of 940 pregnant women who experienced at least one episode of fever were included and compared to 23,811 deliveries who occurred during the same period without documented fever. Among them, 43.7% (411/940) were in labor. About 3.7% (35/940) of febrile pregnant women had at least two episodes of fever, while 0.3% (3/940) had a coinfection at the time of diagnosis, resulting in a total of 978 febrile episodes. Among them, causes remained unknown or uncertain in 7.6% (75/978) and 0.9% (9/978) of cases, respectively. Among confirmed causes of fever throughout pregnancy (n = 483), the most common known cause was arbovirus infection (146/483, 30.2%), followed by urinary tract infection (134/483, 27.7%), chickenpox (27/483, 5.6%), and gastrointestinal (14/483, 2.9%) and pulmonary infections (10/483, 2%). Mothers with fever had a higher risk of cesarean section (19.8% vs 15.5%, aOR 1.3 [95% CI 1.14–1.6], stillbirth (5.5% versus 1.9%, aOR 2.7 [95% CI 2–3.7]), and preterm delivery < 34 weeks of gestation (7.2% vs 4.7%, aOR 1.5 [95% CI 1.2–2].

Conclusions

In the Amazon region, causes of fever are diverse and often associated with epidemic waves, notably arboviruses. This must be considered when exploring possible causes of fever during pregnancy in these localities, including fetal anomalies and/or fetal loss. Physicians should consider the epidemiological context and avoid generalizations. Given the impact of emergent agents such as arboviruses on pregnancy, particular attention must be paid to the epidemiological context. This study can also help clinicians when managing fever in pregnant travelers or in their partner after having visited exposed areas. In this context, fetal abnormalities and adverse obstetric outcomes should be explored accordingly.
Assessing the relationship between early maladaptive schemas and interpersonal problems using interpersonal scenarios depicting rejection
Authors: Janovsky Thomas , Rock Adam J. , Thorsteinsson Einar B. , Clark Gavin I. , Polad Valerie , Cosh Suzanne
Published: October 2023

Background

Early maladaptive schemas (EMSs) have been theorised to contribute to reoccurring interpersonal problems. This study developed a novel experimental paradigm that aimed to assess if EMSs moderate the impact of interpersonal situations on interpersonal responses by manipulating the degree of rejection in a series of interpersonal vignettes depicting acceptance, ambiguous rejection and rejection.

Method

In a sample of 158 first-year psychology students (27.2% male; 72.2% female; 0.6% other) participant responses to interpersonal scenarios were measured including degree of perceived rejection, emotional distress, conviction in varying cognitive appraisals consistent with attribution theory and behavioural responses to scenarios. Qualitative data was analysed using inductive content analysis and statistical analyses were conducted using multi-level mixed effect linear and logistic regression models using the software Jamovi.

Results

People reporting higher EMSs reported increased emotional distress (F(1, 156) = 24.85, p < .001), perceptions of rejection (F(1, 156) = 34.33, p < .001), self-blame (F(1, 156) = 53.25, p < .001), other-blame (F(1, 156) = 13.16, p < .001) and more intentional (F(1, 156) = 9.24, p = .003), stable (F(1, 156) = 25.22, p < .001) and global (F(1, 156) = 19.55, p < .001) attributions but no differences in reported behavioural responses. The results also supported that EMSs moderate the relationship between interpersonal rejection and perceptions of rejection (F(2, 1252) = 18.43, p < .001), emotional distress (F(2, 1252) = 12.64, p < .001) and self-blame (F(2, 1252) = 14.00, p < .001).

Conclusion

Together these findings suggest that people with EMSs experience increased distress and select negative cognitions in situations where there are higher levels of rejection but that distress and negative cognitions are generally higher in people with EMSs irrespective of the situation.
2021 GIS Data for Bedrock Geologic Map of the Indianapolis 30 x 60 Minute Quadrangle, Central Indiana
Authors: Hasenmueller Walter , Johnson Matthew , Bissey Dana
Published: October 2023

The 2021 GIS Data for Bedrock Geologic Map of the Indianapolis 30 x 60 Minute Quadrangle, Central Indiana is an Esri File Geodatabase that contains two feature data sets and four geodatabase tables detailing the bedrock geology of the Indianapolis 30 x 60 Minute Quadrangle in central Indiana. This data set conforms to "GeMS (Geologic Map Schema)--a standard format for the digital publication of geologic maps." For more information on GeMS, please refer to the supplemental information within this metadata. This was a conversion from paper map to GeMS-compliant GIS data. (Hasenmueller, W. A., and James, C. L., 2003, Bedrock geologic map of the Indianapolis 30 X 60 minute quadrangle, central Indiana: Indiana Geological Survey Open-File Study 03-07)
The Bedrock Geologic Map of the Indianapolis 30 x 60 Minute Quadrangle, Central Indiana was created to present basic bedrock geologic information that contributes to the characterization of potential aggregate resources, characterization of bedrock aquifer systems, and analysis of the overlying predominantly glacial deposits. This map is based on data obtained from several thousand records including petroleum well drillers' logs, geophysical logs, water well drillers' logs, descriptions of cores recovered by the Indiana Geological and Water Survey, seismic refraction records collected by the Indiana Geological and Water Survey, natural exposures in and near the map area, and exposures in active and abandoned quarries. This database is, in large part, the result of a cooperative mapping agreement between the U.S. Geological Survey (USGS) and the Indiana Geological and Water Survey through the STATEMAP program of the USGS.
The Bedrock Geologic Map of the Indianapolis 30 x 60 Minute Quadrangle, Central Indiana is a composite geodata set that conforms to "GeMS (Geologic Map Schema)--a standard format for the digital publication of geologic maps," available at http://ngmdb.usgs.gov/Info/standards/GeMS/. Metadata records associated with each element within the geodata set contain more detailed descriptions of their purposes, constituent entities, and attributes. An OPEN shapefile version of the data set is also available. It consists of shapefiles, DBF files, and delimited text files and retains all information in the native geodatabase, but some programming will likely be necessary to assemble these components into usable formats.
Exploring fruitful links between real-world laboratory and disciplinary research: Introduction of the DKN Future Earth working group LinkLab
Authors: Weiser Annika , Wanner Matthias , Stelzer Franziska , Lang Daniel J. , Berger Hilke , Förster Agnes , Liedtke Christa , Micklitz Hans-Wolfgang , Niewöhner Jörg , Parodi Oliver , Potthast Thomas , Schneider Flurina , Sörgel Franziska , Ziehl Michael , Ziemer Gesa
Published: October 2023

LinkLab is a newly established working group under the umbrella of German Committee Future Earth (DKN Future Earth). It opens up a space to discuss relevant connections and interfaces between real-world lab research and various scientific disciplines, exploring fruitful
connections and pathways for mutual learning for future sustainability-oriented research.
The debate on nuclear energy for sustainability: A comment
Authors: Engler John-Oliver , von Wehrden Henrik
Published: October 2023

The role of nuclear energy to cut down on greenhouse gas emissions continues to be a contentious issue in many countries. Public debate is often convoluted and largely revolves around price and costs of energy production technologies as well as their contribution to climate change.
Here, we first dissect two interwoven factors bound to produce confusion in the price-cost debate: temporal discounting and external costs. We then explore how a stronger focus on risk ethics could contribute to the debate on nuclear energy for sustainability.
Individual Abilities of Managers sebagai Mediasi Pengaruh Self-Leadership terhadap Entrepreneurial Intention pada Generasi Millenial Kota Malang
Authors: Anam Choirul , Sudarmiatin Sudarmiatin , Hermawan Agus
Published: October 2023

This paper explains Individual Abilities of Managers as a mediation of the influence of Self-Leadership on Entrepreneurial Intention in the Millennial Generation of Malang City. Types of quantitative research with explanatory research methods. The sample taken was millennials as many as 161 respondents. data collection with questionnaires and using Smart-PLS as its analysis tool. The results showed that Self Leadership directly has a significant effect on Entrepreneurial Intention. Furthermore, Self Leadership has a significant effect on Individual Abilities of Managers has a significant effect on Entrepreneurial Intention. Then, Individual Abilities of Managers have a significant effect on Entrepreneurial Intention. Finally, Individual Abilities of Managers are indirectly capable of being partial mediating variables.Artikel ini menjelaskan Individual Abilities of Managers sebagai mediasi pengaruh Self-Leadership terhadap Entrepreneurial Intention pada generasi Millenial Kota Malang. Jenis penelitian kuantitatif dengan metode explanatory research. Sampel yang diambil adalah generasi millenial sebanyak 161 responden. Pengumpulan data dengan kuesioner dan menggunakan Smart-PLS sebagai alat analisisnya. Hasil penelitian menunjukkan bahwa secara langsung Self Leadership berpengaruh signifikan terhadap Entrepreneurial Intention. Selanjutnya, Self Leadership berpengaruh signifikan terhadap Individual Abilities of Managers berpengaruh signifikan terhadap Entrepreneurial Intention. Kemudian,  Individual Abilities of Managers berpengaruh signifikan terhadap Entrepreneurial Intention. Terakhir, Individual Abilities of Managers secara tidak langsung mampu menjadi variabel mediasi bersifat mediasi sebagian.
Why Personal Characteristics of Innovative Leadership Can Drive Organizational Competitive Advantage? A Literature Review with Integrative Approach
Authors: Asrarudin Asrarudin -
Published: October 2023

This research is qualitative research that investigates the multi-characteristics of innovative leadership that drives the organization's competitive advantage by applying an integrative review of literature approach. Data and information are adopted from research outputs published in indexed and reputable journals in 2012-2021. Based on several articles reviewed the author found that there are three core competencies of innovative leaders: managerial, conceptual and team-building skills. These embedded competencies can shape innovative attitude and behaviour of subordinates which consistently and sustainably will enhance individual and collective productivity.   In the long term it can boost organizational competencies in all level of management hierarchy. Personal characteristics of innovative leader consist of (1) clear and strong vision; (2) consistent integrity; (3) partnership working; (4) two-way communication; (5) managing uncertain changing environments; (6) thinking creatively and innovatively; (7) understand the issues comprehensively; (8) problems solving; (9) positive and energetic thinking; (10) mental health stability; and (11) adequate physical health. In principle, personal characteristics of characteristic of innovative leader consist of hard and soft personal unique competencies. The results of this research study reveal that the personal characteristics of innovative leadership as a role model are able to build subordinates' innovative behaviour which is consistently and continuously able to increase the organization's competitive advantage.
Reinvensi New Governance Bisnis Buah Mangga Berkelanjutan (Studi pada Ekonomi Buah Mangga Gedong di Jawa Barat, Indonesia)
Authors: Muftiadi Anang , Ryanto Heru , Santoso Teguh , Pardian Pandi , Akbar Adhadian , Meliani Mia
Published: October 2023

Success and sustainability of business requires alignment of institutions and the ecosystem.  Aligment weaknesses in Gedong Mango fruit, from Sumedang, Jawa Barat coincide with export market prospect to Japan and high  value-added of processing .  Therefore a new governance framework is required. This study aims to calculate the value added in value chain using the Hayami Method and mapping power and interests of stakeholders. as foundation of new a governance system. The results show that the economy of Gedong  Mango Sumedang is evolutionarily disadvantageous for position and income of farmers, as indicated by un-even distribution of value-added in the supply chain and uncertainty of direction of change. The negative impact is that the prospect of  large market will not be able to increase and balancing income and welfare of farmers and other stakeholders. A new business governance  transformed by positioning the cooperative as a node of relationship and as driver, which is directed by a committee of stakeholder representatives with government facilitation.Keberhasilan dan keberlanjutan bisnis membutuhkan kelembagaan yang selaras dengan ekosistem. Kelemahan dalam hal tersebut dihadapi oleh produk buah Mangga Gedong dari Sumedang Jawa Barat, ketika prospek pasar ekspor ke Jepang dan nilai tambah hasil pengolahannya tinggi. Untuk itu, diperlukan suatu kerangka governance baru yang tepat. Penelitian ini bertujuan menghitung nilai tambah dan rantai nilai Mangga Gedong menggunakan Metode Hayami dan memetakan power dan interest para stakeholders menjadi suatu sistem governance. Hasil penelitian menunjukkan bahwa perkonomian Mangga Gedong Sumedang secara evolutif kurang menguntungkan posisi dan pendapatan petani yang ditunjukkan oleh ketidakseimbangan distribusi nilai tambah pada rantai pasok dan ketidakpastian arah perubahan. Dampak negatifnya, prospek pasar yang besar tidak akan dapat meningkatkan pendapatan dan kesejahteraan petani dan stakeholders lain secara seimbang. Karena itu diperlukan new business governance formdengan cara memposisikan koperasi sebagai simpul relasi dan driver yang diarahkan oleh komite para wakil stakeholders dengan fasilitasi pemerintah.
Report on a case of liver-originating malignant melanoma of unknown primary
Authors: Yuan Zheng , Guo Hai-yan , Lu Wei-ting , Wang Yao-hui , He Jing , Zhang Fan , Che Jun-yong , Qiao Fei
Published: October 2023

Malignant melanoma (MM) frequently occurs in the skin or mucosa, whereas malignant melanoma of unknown primary (MUP) is diagnosed in patients with lymph nodes or visceral organs as the site of origin, where it is challenging to detect the primary lesion by comprehensive examination. MUP is possibly related to the spontaneous regression of the primary lesion. In addition, primary hepatic melanoma (PHM) usually refers to the primary MM occurring in the liver, with no typical primary lesions and no manifestations of tumor metastasis. A 61-year-old male patient with liver as the site of origin was diagnosed with MM by Melan-A, HMB-45, and S-100 immunohistochemistry staining of liver biopsy tissue. Based on a comprehensive examination, no basis was found for melanoma in sites such as the skin, mucosa, five sense organs, brain, digestive tract, respiratory tract, or genitalia, and the patient was subsequently diagnosed with MUP. MMs require a comprehensive inspection, beginning with the liver, to search for the primary lesion; if the primary lesion is not found, the possibility of PHM or MUP should be considered.
Research on the artificial control method of the gas nuclei spectrum in the small-scale experimental pool under atmospheric pressure
Authors: Yang Meicheng , Yang Lijia , Li Daojiang , Jiang Zhiyong , Hou Shuo , Li Haichao
Published: October 2023

With the improvement of the accuracy of experimental devices and measuring instruments, cavitation experiments such as cross-media vehicles and propellers have been carried out in small pools. However, the water quality in the laboratory and the engineering application waters differs, especially the concentration of the gas nuclei that cause cavitation, resulting in experimental results that differ from prototype experimental results, and the scale effect occurs. In order to reduce the influence of the scale effect, according to the conditions of cavitation, gas nuclei can be mixed with water before the experiment is formally implemented. Aeration behavior will affect the size and concentration of gas nuclei (gas nuclei spectrum) in water. In order to obtain better experimental results, it is necessary to clarify the variation of the gas nuclei spectrum in small-scale experimental pools before and after aeration, so as to master aeration technology. Through research, it is found that the artificial aeration method can effectively change the gas nuclei spectrum in water and increase the concentration of gas nuclei. By using the underwater acoustic measurement method, the change in the gas nuclei spectrum can be captured sensitively. The gas nuclei spectrum in water after aeration is in good agreement with the mathematical model of gas nuclei spectrum under non-artificial intervention, which shows that the distribution of gas nuclei in water under artificial aeration is similar to that under non-artificial intervention, which is conducive to the occurrence of cavitation. At the same time, it shows that the combination of experiment and numerical method can reduce the measuring state and the measurement cost and improve the measurement efficiency.
The Japanese Pursuit of Human–Robot Companionship
Authors: Katsuno Hirofumi , White Daniel
Published: October 2023

Building on global advances in artificial emotional intelligence, Japanese companies have increasingly invested in developing social robots with capacities to express and evoke emotion. In some cases, they can even read the emotional expressions of human users. These efforts parallel a broader trend in state support for developing technological solutions to socioeconomic problems, such as social isolation and a deficit in care workers. The rise of companion robots has elicited excitement about potential futures of human–robot existence as well as concerns over data privacy and the loss of inter-human connection, embodying the dynamic emotional dimensions of Japan’s social transformation.
Saving Nature and Ourselves
Authors: Woodhouse Keith Makoto
Published: October 2023

If exploitation of nonhuman nature is bound up with the exploitation of other humans, how can these chains be broken?
Acute heart failure with incidentally found cystic adrenal mass
Authors: Bhat Salman Zahoor , Hamrahian Amir H , Wu Yubo , Han Misop , Salvatori Roberto
Published: October 2023

Pheochromocytomas are rare adrenal tumors characterized by excessive catecholamine secretion. Symptoms and signs associated with pheochromocytomas are usually intermittent and chronic but can rarely develop into life-threatening crises. We describe a case of acute severe congestive heart failure in a previously healthy female, who recovered rapidly (4 days after admission) with acute medical therapy. The etiology on evaluation was a spontaneous bleed in a previously undiagnosed pheochromocytoma, resulting in a pheochromocytoma crisis and transient stress cardiomyopathy, followed by quick recovery of cardiac function. Our aim is to describe pheochromocytoma as a rare cause of stress cardiomyopathy. We discuss the evaluation of pheochromocytoma during critical illness and triggers/treatment strategies for pheochromocytoma crises.

Learning points

Hemorrhage in a pheochromocytoma can result in a pheochromocytoma crisis, with sudden release of excess catecholamines resulting in multisystem organ dysfunction and high mortality.

Acute decompensated heart failure can be a rare presentation of pheochromocytoma, in a patient with no cardiac risk factors.

Measurement of metanephrines in acutely stressful clinical situations can have considerable overlap with the biochemical picture of pheochromocytoma. Early imaging studies may help with the differential diagnosis.

Pheochromocytoma should be ruled out before performing an adrenal biopsy.

Emergent adrenalectomy in pheochromocytoma crisis results in high mortality. Medical management of the acute crisis followed by elective adrenalectomy after alpha-blockade results in better outcomes.
Microbiota-associated mechanisms underlying sexual dimorphism in hypertension
Authors: Dasinger John Henry , Joe Bina , Abais-Battad Justine M
Published: October 2023

Consistent research over the last 20 years has shown that there are clear sex differences in the pathogenesis of hypertension, the leading risk factor for the development of cardiovascular diseases. More recently, there is evidence in both humans and experimental animal models that causally implicates the gut microbiota in hypertension. It therefore follows that sex differences in the gut microbiota may mediate the extent of disease between sexes. This new field is rapidly changing and advancing, and the purpose of this review is to cover the most up-to-date evidence regarding the sexual dimorphism of the gut microbiota and its potential influence on the differential manifestation of hypertension in males versus females. Emphasis will be placed on the mechanisms thought to contribute to these sex differences in both the gut microbiota and hypertension, including sex steroid hormones, gut-derived metabolites, the immune system, and pregnancy.
Regional abundances of binder of sperm (BSP) proteins are negatively associated with the quality of frozen-thawed bovine spermatozoa
Authors: Diaz-Miranda Edgar A , Hamilton Lauren E , Zigo Michal , Fallon Lindsey , Ortega M Sofia , D’Avila Assumpção Mayra E Ortiz , Guimarães José D , Sutovsky Peter
Published: October 2023

In brief

The localization and abundance of the sperm BSP proteins correlate with in vitro fertility in domestic bulls used in artificial insemination service.

Binder of sperm (BSP) proteins, secreted mainly by the accessory sex glands, are the major protein family present in bovine seminal plasma and on the sperm surface after ejaculation. In vivo, BSP proteins facilitate sperm capacitation and sperm reservoir formation; however, their impact on sperm function within the in vitro systems is less clear. Therefore, this biomarker-based study aimed to characterize the localization and abundance of BSP proteins from in vitro processed frozen-thawed bovine spermatozoa. Using image-based flow cytometry and Western blotting, BSP protein localization, abundance, membrane and acrosomal integrity were investigated in the supernatant (nonmotile) and pellet (motile) fractions of gradient-separated bull spermatozoa. Spermatozoa from the supernatant fraction had high enrichment of all BSP proteins investigated (BSP1, BSP3, BSP5; P < 0.05) when compared to the pellet fraction. In the pellet fraction, BSP1 and BSP3 bound predominately to the acrosomal region, whereas BSP5 had a high affinity for the midpiece. However, in the supernatant fraction, BSP proteins predominately coated the entire sperm surface resulting in the loss of regional specificity. High BSP protein abundance in the spermatozoa also correlated with acrosome and membrane damage. Whereas a high abundance of BSP5 correlated with low embryo cleavage rates, high abundance of BSP1 on the sperm head coincided with a high blastocyst rate. Therefore, changes in the quantity and localization of specific BSP proteins could act as potential biomarkers of sperm quality and fertility.
Anastomosis between the facial nerve – ansa cervicalis and the facial nerve – hypoglossal nerve in rabbits: technical note for a practical use in peripheral facial palsy
Authors: Balaci Georgeta Magdalena , Major Zoltan Zsigmond , Radu Oana Maria , Sălăgean Raul , Florian Ioan Ștefan
Published: October 2023

Background and aims. To emphasize the importance of laboratory dissections in perfecting surgical techniques. In this paper, we describe the technical details on rabbit dissection for practical applications.

Methods. Four New Zealand rabbits were distributed into two groups and underwent anastomosis between the Facial Nerve and Ansa Cervicalis (group 1) and between the Facial Nerve and Hypoglossal Nerve (group 2). They were clinically and neurophysiologically evaluated after ten weeks. Electroneurography with skin electrodes were used to identify the motor activity of the involved muscles and nerves. Facial and ipsilateral tongue reinnervation was analyzed 40 weeks after anastomosis. Evoked electromyographic muscle tension was used to evaluate facial and tongue reinnervation.

Results. Facial and ipsilateral tongue reinnervation was analyzed 40 weeks after anastomosis. Recorded evoked potentials showed improvement in facial reinnervation in all four rabbits. Rabbits undergoing FN-HN anastomosis still showed ipsilateral lingual paresis, based on EMG tests. The survival rate was 100%.

Conclusions. The laboratory dissection plays a crucial role in training surgical specialists to achieve favorable patient outcomes. Both types of anastomosis can be used to achieve facial reinnervation; however, it is imperative to prevent ipsilateral lingual paralysis that may arise from using the hypoglossal nerve.
The concept of "physical culture and health technology" in the practice of a physical therapist
Authors:   Sumy State Pedagogical University named after A. S. Makarenko, Avramenko N.B. , Bespalova O.O. ,   Sumy State Pedagogical University named after A. S. Makarenko, Bugayenko T.V. ,   Sumy State Pedagogical University named after A. S. Makarenko
Published: October 2023

Purpose: systematization of approaches to the interpretation of the concept of "physical culture and health technologies", study of the main stages of their development, structure and basic components. Material and methods: analytical analysis of scientific and methodical literature, generalization of research results of individual authors. Results: in the process of analyzing the scientific and methodological literature, approaches to the formulation of the concept of "physical culture and health technologies" in the field of physical therapy (rehabilitation) and physical culture were analyzed. Conclusions: it was found that physical culture and health technologies are a dynamic system that is constantly developing and changing, has its own structural components, stages of development, and is aimed at improving health, preventing diseases or restoring damaged functions.
Real-Time Digital Feedback Device and Simulated Newborn Ventilation Quality
Authors: Data Santorino , Nelson Brett D. , Cedrone Kevin , Mwebesa Winifride , Engol Santa , Nsiimenta Naome , Olson Kristian R.
Published: October 2023

OBJECTIVES

Effective bag-valve-mask ventilation is critical for reducing perinatal asphyxia-related neonatal deaths; however, providers often fail to achieve and maintain effective ventilation. The Augmented Infant Resuscitator (AIR) attaches to bag-valve-masks and provides visual feedback on air leaks, blocked airways, harsh breaths, and improper ventilatory rates. We evaluated the effect of this real-time-digital feedback on ventilation quality and the effective determination of airway integrity in a randomized controlled study in Uganda and the United States.

METHODS

Birth attendants trained in newborn resuscitation were randomized to receive either real-time AIR device feedback (intervention) or no feedback (control) during ventilation exercises. Intervention-arm participants received a 2-minute orientation on interpreting AIR feedback using a single-page iconography chart. All participants were randomly assigned to 3 blinded ventilation scenarios on identical-appearing manikins with airways that were either normal, significantly leaking air, or obstructed.

RESULTS

We enrolled 270 birth attendants: 77.8% from Uganda and 22.2% from the United States. Birth attendants receiving AIR feedback achieved effective ventilation 2.0 times faster: intervention mean 13.8s (95% confidence interval 10.6–17.1) versus 27.9s (21.6–34.3) for controls (P < .001). The duration of effective ventilation was 1.5 times longer: intervention mean 72.1s (66.7–77.5) versus 47.9s (41.6–54.2) for controls (P < .001). AIR feedback was associated with significantly more accurate and faster airway condition assessment (intervention mean 43.7s [40.5–47.0] versus 55.6s [51.6–59.6]).

CONCLUSIONS

Providers receiving real-time-digital AIR device feedback achieved effective ventilation significantly faster, maintained it longer, and determined airway condition faster and more accurately than providers in the control group.
Féléves csecsemők temperamentumának mérése a Csecsemőviselkedés Kérdőív 15 tételével: pszichometriai elemzés és korrelátumok
Authors: Sándor Nikolett Gabriella , Kopcsó Krisztina , Pohárnok Melinda
Published: October 2023

Elméleti háttér: A temperamentum születésünktől fogva megjelenő diszpozíció. Fejlődése és kialakulása folyamatos, így már csecsemőkorban fontos a mérése. A szakirodalomban számos elmélet született a csecsemőkori temperamentumtípusok azonosítására és jellemzésére. Cél: Kutatásunk célja a tételszelekcióval előállított Csecsemőviselkedés Kérdőív 15 válogatott tétele pszichometriai jellemzőinek vizsgálata magyarországi reprezentatív mintán. Módszerek: Az elemzést a Kohorsz ’18 Magyar Születési Kohorszvizsgálat második szakaszában részt vevő 5-7 hónapos csecsemők (átlagéletkor = 5,74 hónap, SD = 0,51 hónap) adatain végeztük (n = 8104). A csecsemő viselkedését és temperamentumjellemzését az Infant Behavior Questionnaire-R-Very Short Form 37 tételes kérdőívből előállított Csecsemőviselkedés Kérdőív 15 válogatott tételével mértük. A kérdőív szülői megfigyelésen alapul. A kérdezés szóban, az illetékes védőnő által történt. Eredmények: A kérdőív háromfaktoros szerkezete (Pozitív affektivitás/Lendületesség, Negatív affektivitás, Orientációs és regulációs kapacitás, amelyekhez 5–5 tétel tartozik), feloldva két tétel hibakorrelációjának tilalmát, megfelelő illeszkedést mutatott (RMSEA = 0,047 [90% CI: 0,045; 0,049]; Gamma Hat = 0,975; SRMR = 0,041; χ2(86) = 1625,54; CFI = 0,910; TLI = 0,890). A Pozitív affektivitás/Lendületesség (Cronbach-α = 0,55) és Orientációs és regu lációs kapacitás (Cronbach-α = 0,53) skálák belső konzisztenciája egyaránt gyenge, míg eloszlásuk a magas értékek felé tolódik el. A Negatív affektivitás alskála belső konzisztenciája megfelelő (Cronbach-α = 0,72), eloszlása a normálishoz közelít. A temperamentumtípusok azonosítására végzett klaszteranalízis alapján négy típust különítettünk el, amelyek az Átlagos temperamentumú (n = 2516, 31,6%), a Könnyű temperamentumú (n = 2229, 28,0%), a Nehéz temperamentumú (n = 1896, 23,8%) és az Alacsony aktivitású (n = 1325, 16,6%) csecsemők. A kis születési súly, illetve az, ha az anya megterhelőnek érzi a csecsemő alvási szokásait és sírását, összefüggést mutatott a nehezebb temperamentum és alacsonyabb aktivitás felé mutató temperamentumjellemzőkkel. Következtetések: A Csecsemőviselkedés Kérdőív 15 válogatott tétele alimitációk mérlegelése mellett lehetőséget nyújt a csecsemőkori temperamentum gyors felmérésére ésa jelen tanulmányban bemutatott reprezentatív adatokhoz való viszonyítására.
Can Health Authorities Stop the Medicalisation of Childbirth? The Case of Spain in the Early 20th Century
Authors: Ruiz-Berdún Dolores , Hossain-López Sheima
Published: October 2023

The medicalisation of childbirth is a worldwide trend, that has its roots in past centuries. Despite being a widely studied phenomenon, the attempts taken to prevent its spread have rarely been addressed. This research presents the measures taken by the health authorities against the medicalisation of childbirth in Spain, in the early twentieth century. The episode was linked to a famous obstetrician, Miguel Orellano, who published several papers advocating a new method of conducting a delivery. This method involved a great deal of unnecessary intervention that turned delivery into a major surgical procedure. We will see if the health authorities have achieved their goal.
Implementing ISO 14001 in the engineering and construction sectors: a systematic review
Authors: Horry Rosemary E , Booth Colin A , Mahamadu Abdul-Majeed , Ball Sophie
Published: October 2023

There is a need within society to manage its impacts on the environment. The International Organization for Standardization (ISO) ISO 14001 tool, based on the original BS 7750 standard, was created in 1996 and subsequently updated in 2004 and 2015; it has become the most prevalent type of environmental management system (EMS) adopted worldwide. Engineering and construction organisations wanting to implement ISO 14001 should be fully acquainted with the advantages and disadvantages of adopting an EMS. Using the Scopus academic database, this study used the Preferred Reporting Items for Systematic Reviews and Meta-analyses method to identify and select publications (since 1999) for systematic review. Examination of the chosen articles (n = 46) revealed a limited number of works per annum, with a peak in 2011 (n = 6). The most frequently reported benefits are ‘enrichment of green corporate and public image’, ‘improved environmental performance’ and ‘regulation compliance’, while the barriers are ‘costs’, ‘lack of experience, expertise or knowledge’ and ‘lack of training’. Further analysis, using the VOSviewer software, shows the network relationships between article keywords, notably that sustainability is increasingly listed (since 2011) and links with most other keywords. This suggests that the engineering and construction sectors may be seeing beyond the cost barrier and are realising the positive difference that ISO 14001 can contribute to their operations, their local/national communities and the UN Sustainable Development Goals.
Influence of injection methods on bio-mediated precipitation of carbonates in fracture-mimicking microfluidic chip
Authors: Zhao Chang , Xiao Yang , He Xiang , Liu Hanlong , Liu Yi , Chu Jian
Published: October 2023

Enzymatically induced carbonate precipitation (EICP) is a potential method to alter the hydraulic properties of fractured rocks. The pore-scale in situ formation of bio-mediated precipitated carbonates in fracture-mimicking channels was investigated experimentally through a visualisation platform and microfluidic technology. Image processing was employed to analyse the precipitation behaviour. Three representative biogrouting methods (one-phase continuous injection, one-phase staged injection and two-phase staged injection) and the role of nucleation agents were examined in this study. Results revealed that more amorphous substances formed during the one-phase injection process, and the one-phase staged injection method exhibited superior precipitation efficiency, whereas the two-phase staged injection method demonstrated better effectiveness in channel clogging. The addition of nucleation agents resulted in a channel-like precipitation pattern, compared to the formation of more crystals in the absence of additives. The hydrodynamic coupling between precipitation and flow velocity was used to explain the mechanisms of fracture sealing. Precipitation and aggregation led to the reduction in microchannel aperture, thereby influencing the flow field. Under flow-induced shearing, the amorphous substances could be transported and settled on the channel surface, leading to a self-enhancing process in channelling. This study provides insights into the microscopic mechanisms of EICP and advances the application of EICP in fracture repair.
Efeitos da realidade aumentada na aprendizagem das ciências naturais: uma revisão sistemática da literatura
Authors:   Instituto de Educação, Universidade de Lisboa, Faria António , Miranda Guilhermina Lobato ,   Instituto de Educação, Universidade de Lisboa
Published: October 2023

Este artigo apresenta os resultados de uma revisão sistemática da literatura sobre os efeitos da utilização da realidade aumentada (RA) na aprendizagem dos estudantes de ciências (Ciências Naturais e Biologia) do 3.ºciclo do ensino básico e do ensino secundário. Foi utilizada a metodologia PRISMA, tendo sido selecionados 10 artigos de revistas indexadas, num período de tempo entre 2010 e 2022. As bases de dados consultadas foram Scopus, ScienceDirect, Springer Link, EBSCO e Web of Science. A maioria dos artigos selecionados (n=8), após a aplicação dos critérios de inclusão e exclusão, utilizou uma metodologia experimental. Os resultados indicam que a RA teve efeitos positivos na aprendizagem e motivação dos estudantes, bem como noutras variáveis como as competências visuoespaciais e o envolvimento dos estudantes nas tarefas de aprendizagem.