bluuebunny/crossref_metadata_2025 huggingface dataset:
Interactions between Macrophages and Cyst-Lining Epithelial Cells Promote Kidney Cyst Growth in Pkd1-Deficient Mice
Authors: Yang Yang , Chen Meihan , Zhou Jie , Lv Jiayi , Song Shuwei , Fu LiLi , Chen Jiejian , Yang Ming , Mei Changlin
Published: July 2018

Background

Autosomal-dominant polycystic kidney disease (ADPKD) is the leading inherited renal disease worldwide. The proproliferative function of macrophages is associated with late-stage cyst enlargement in mice with PKD; however, the way in which macrophages act on cyst-lining epithelial cells (CLECs) has not been well elucidated.

Methods

We generated a rapid-onset PKD mouse model by inactivatingPkd1on postnatal day 10 (P10) and compared cell proliferation and differential gene expression in kidney tissues of the PKD mice and wild-type (WT) littermates.

Results

The cystic phenotype was dominant from P18. A distinct peak in cell proliferation in polycystic kidneys during P22–P30 was closely related to late-stage cyst growth. Comparisons of gene expression profiles in kidney tissues at P22 and P30 in PKD and WT mice revealed that arginine metabolism was significantly activated; 204 differentially expressed genes (DEGs), includingArg1, an arginine metabolism–associated gene, were identified in late-stage polycystic kidneys. TheArg1-encoded protein, arginase-1 (ARG1), was predominantly expressed in macrophages in a time-dependent manner. Multiple-stage macrophage depletion verified that macrophages expressing high ARG1 levels accounted for late-stage cyst enlargement, and inhibiting ARG1 activity significantly retarded cyst growth and effectively lowered the proliferative indices in polycystic kidneys.In vitroexperiments revealed that macrophages stimulated CLEC proliferation, and that L–lactic acid, primarily generated by CLECs, significantly upregulated ARG1 expression and increased polyamine synthesis in macrophages.

Conclusions

Interactions between macrophages and CLECs promote cyst growth. ARG1 is a key molecule involved in this process and is a potential therapeutic target to help delay ADPKD progression.
A consciência textual no gênero fábula: um instrumento de verificação da coerência com alunos do Ensino Fundamental
Authors: Neves Patricia De Andrade , Borges Caroline Bernardes
Published: July 2018

Resumo: Os resultados das provas nacionais oficiais mostram que cada vez mais os alunos têm dificuldade na compreensão de textos. Dentre as possíveis razões, há o elevado índice de analfabetismo entre os alunos dos anos iniciais e o desempenho apenas básico de leitura entre os alfabetizados. Tendo como ponto de partida esse cenário educacional, o propósito deste artigo é a apresentação e a análise de um instrumento de verificação da consciência textual (Gombert, 1992), no que se refere à coerência (Charolles, 1978), utilizando a fábula, um gênero textual de estrutura predominantemente narrativa (Adam, 2011), que possa ser aplicado em alunos do 6º ano do Ensino Fundamental. Com esse objetivo, após a apresentação do instrumento de verificação, cada questão é analisada sob o viés dos estudos citados, de modo a contribuir com uma ferramenta para os professores que favorece o conhecimento da situação de consciência textual de seus alunos.
Processamento em leitura, estratégias metacognitivas e ensino: revisitando os temas
Authors: Dania Rejane Croharé
Published: July 2018

Á luz da psicolinguistica, o presente artigo tematiza leitura, processamento em leitura e o ensino de estrategias metacognitivas em contexto escolar brasileiro. Descreve-se pesquisa realizada em escola pública no ano de 2005, na capital de Santa Catarina. Buscou-se indentificar o perfil dos sujeitos que completavam a oitava serie, por meio de quatro instrumentos: (1) questionário de identificação para coletar nome, data, local de nascimento e se era aluno repetente; (2) levantamento psicossociolingüístico para descobrir hábitos de leitura e escrita dos participantes; (3) pré-teste para avaliar o desempenho em leitura antes da intervenção e (4) pós-teste para avaliar o desempenho após a intervenção. Partiu-se dos resultados de desempenho em leitura do Programa Internacional de Avaliação de Alunos (PISA, 2000) e do Índice de Analfabetismo Funcional (INAF, 2001, 2003 e 2005) que mostram que os brasileiros leem, mas estão limitados a localizar e recuperar informações explícitas. A hipótese alternativa defendida nesta pesquisa é que alunos submetidos a um programa de leitura e uso de estratégias metacognitivas apresentam melhor desempenho em leitura. Os dados empíricos serviram para testar as hipóteses após a análise quantitativa, estatística e qualitativa. Os resultados quantitativos do pós-teste mostraram variabilidade nos escores. O tratamento estatístico dos dados possibilitou afirmar que houve diferença significativa entre o pré e o pós-teste, confirmando a hipótese alternativa desta pesquisa.
A Living Wage: American Workers and the Making of Consumer Society
Authors: Kolnick Jeffrey
Published: July 2018

Review of: A Living Wage: American Workers and the Making of Consumer Society. Glickman, Lawrence B.
I believe I can do science: Self-efficacy and science achievement of Grade 9 students in South Africa
Authors: Juan Andrea , Hannan Sylvia , Namome Catherine
Published: July 2018

An important component of an individual’s scientific literacy is a positive attitude towards science. However, emphasis is too often placed on achievement scores rather than attitude. While individuals’ relative levels of problem-solving skills, inherent aptitudes for the subject matter and teaching practices are conveyed through achievement scores, attitudes to science convey individuals’ emotional evaluation of the subject. Attitudes have a strong impact on behaviour: through either facilitating the learning process or hindering it. Furthermore, attitudes towards science reflect the culture which exists within a school, as well as the wider social context within which learning takes place. As a result, understanding attitudes is a key component of the interpretation of achievement results. We used data from 12 514 Grade 9 students in South Africa who participated in the 2015 Trends in International Mathematics and Science Study to investigate students’ self-efficacy in science. Multiple linear regression analyses were used to address the following key research questions: (1) What is the relationship between self-efficacy and science achievement for Grade 9 students in South Africa? and (2) What are the contextual factors associated with the self-efficacy of Grade 9 students in South Africa? The findings reveal a positive relationship between self-efficacy and science achievement and suggest a need to also focus on noncognitive aspects in order to improve science achievement.Significance:

The study contributes to understanding the determinants of science performance at school.
The findings highlight the importance of non-cognitive dimensions in science achievement at school.
The findings have policy implications for education programmes and teachers in relation to interventions which incorporate non-cognitive dimensions.

Data set available at: http://curation.hsrc.ac.za/doi-10.14749-1499247520
Spatial distribution of temporal precipitation contrasts in South Africa
Authors: Botai Christina M. , Botai Joel O. , Adeola Abiodun M.
Published: July 2018

The focus of the present study was to investigate the spatial-temporal variability and trends of precipitation concentration across South Africa using the Tropical Rainfall Measuring Mission (TRMM) 3B42 version 7 satellite precipitation data sets spanning 1998–2015. In the analysis, the precipitation concentrationindex (PCI) was used to infer the variability of temporal precipitation contrasts and the spatial distributions at annual, seasonal and supra-seasonal timescales. The results indicate that precipitation concentration across South Africa exhibits noticeable spatial-temporal variability. In terms of PCI classification criteria,the precipitation distribution ranges from relatively uniform (mainly in the central and southern interior of South Africa) to highly irregular (especially to the northeastern and western parts of South Africa) at annual timescales. At seasonal timescales, the precipitation distribution is uniform during December–Februaryseason, moderate during March–May and September–November seasons while during the June–August season, the precipitation distribution is highly irregular. Furthermore, during the 1998–2015 period, there exists a spatial and temporal pattern of PCI trends which are generally statistically insignificant. The PCI analysis results reported in this study are essential because they provide valuable information on the longterm total variability in the precipitation records across South Africa. In particular, this study contributes towards evaluating the spatial contrasts or concentration of the different accumulated amounts of thereceived precipitation. Results from this study have important scientific and practical applications in hydrological hazard risks (floods and droughts) and soil erosion monitoring.Significance:

Precipitation concentration exhibits spatial-temporal variability.

At an annual timescale, precipitation concentration is highly irregular in most parts of the country.

Precipitation concentration distribution varies across seasons.
Efeito do atendimento em grupo na qualidade de vida e capacidade funcional de pacientes após AVC
Authors: Nascimento Hayre Santana , Ribeiro Nildo Manoel da Silva
Published: July 2018

INTRODUÇÃO: O Acidente Vascular Cerebral (AVC) é considerado a segunda doença mais incapacitante do mundo, podendo causar diversas sequelas. Nesse sentido, o atendimento fisioterapêutico em grupo se configura como uma estratégia promissora e viável dentro do processo de reabilitação dos indivíduos acometidos. OBJETIVO: Avaliar o nível de qualidade de vida e capacidade funcional antes e após uma intervenção fisioterapêutica em grupo em pacientes com sequelas de AVC. MÉTODOS: Trata-se de uma análise retrospectiva de prontuários, realizada a partir da coleta de dados referentes à capacidade funcional (Índice de Barthel Modificado), e qualidade de vida (EQVE-AVE) de pacientes vítimas de AVC que realizaram um protocolo de atendimento fisioterapêutico em um ambulatório entre setembro de 2016 até agosto de 2017. RESULTADOS: 27 prontuários atenderam aos critérios estabelecidos. No que tange aos resultados referentes à capacidade funcional dos indivíduos, foi possível notar diferença significativa nos itens de: Alimentação; higiene pessoal; banho; vestir-se, além do score total do Índice de Barthel Modificado. Observou-se também melhora significativa em aspectos referentes a qualidade de vida nos seguintes itens: Energia; linguagem; mobilidade; memória/concentração, além do score total da escala de avaliação EQVE-AVE. CONCLUSÃO: Identificou-se melhora no nível de qualidade de vida e capacidade funcional de indivíduos que sofreram AVC após realização de um protocolo de atendimento fisioterapêutico em grupo em um ambulatório.
Síndrome de Burnout em estudantes de medicina de universidade da Bahia
Authors: Aguiar Ramon Lucas Bomfim de , De Aguiar Márcia Cristina Maciel , Mercês Magno Conceição das
Published: July 2018

Burnout é definido como aquilo que deixou de funcionar por absoluta falta de energia. A Síndrome de Burnout é caracterizada pela exaustão emocional, despersonalização e baixa realização profissional. Os estudantes de medicina são um grupo de risco para o desenvolvimento desta síndrome pela pressão exercida por seu círculo social e familiar, desde a decisão de prestar vestibular para medicina até a conclusão do curso. Objetivo: Descrever a prevalência da Síndrome de Burnout em estudantes de medicina da Universidade do Estado da Bahia (UNEB) e identificar se há variáveis sociodemográficas, acadêmicas e psicossociais a ela associadas. Método: descritivo transversal, realizado com estudantes de medicina da UNEB do 1° ao 8° semestres aplicando-se um questionário para levantamento das variáveis sociodemográficas, acadêmicas e psicossociais e o MBI-SS (Maslach Burnout Inventory/ Student Survey). Utilizou-se para a análise dos dados o programa SPSS – versão 22.0,  OpenEpi e Microsoft Excel 2010. Resultados: A Síndrome teve prevalência de 19,6% na amostra, 35,4% apresentavam risco elevado de desenvolver a síndrome e 26,6% baixo risco. Entre as variáveis estudadas “possuir filhos”, “possuir ocupação atual”, e “pensar em desistir do curso” tiveram associação positiva com significância estatística (p<0,05) com o desenvolvimento da Síndrome de Burnout. Conclusão: há necessidade de implantação de medidas preventivas e curativas no que diz respeito ao alto índice de exaustão emocional, e aos índices médios de descrença, o que poderá levar à diminuição do risco de desenvolvimento da Síndrome de Burnout nestes estudantes.
THE INFLUENCE OF BUSINESS WITH CONTENT ECOMMERCE ON RETAIL BUSINESS TO THE ASPECT MARKETING OF MICRO SMALL MEDIUM IN DEPOK
Authors: Haryono Sugeng , Nurlaela Nurlaela
Published: July 2018

There are many factor that affect the rapid development of online busniness in Indonesia among the more eccommerce users. Associated with this researcher will examine about the influence of business with content ecommerce on retail business to the  aspect marketing of micro small medium in Depok. Specific objectives of this research are 1). To help retail business managers maximize distribution, information and product socialization to be easily accessible by the community so as to be able to compete with business managers with ecommerce content. 2). the process of socialization, product education, marketing and product data processing through e-commerce. As for the results of the research, there is a significant effect of e-commerce content on retail business on the marketing aspect of  Micro Small Medium in Depok
THE EFFECT OF LEADERSHIP STYLE ON AUDITOR PERFORMANCE WITH TRUST IN SUPERIORS AS INTERVENING VARIABLE
Authors: Budiman Nita Andriyani
Published: July 2018

This study aims to examine the influence of leadership styles (transformational and traksaksional) on the performance of auditors (in-role performance and extra-role performance) in the Javanese of public accounting firm through trust in superiors as intervening variables. This study uses questionnaires as a method of collecting data provided to 96 respondents spread across 19 public accounting firm all Java. Hypothesis analysis in this research is conducted by using multiple regression analysis. The results obtained in this study include that the style of transformational leadership does not affect on trust in superiors while the leadership style of transactional positive effect on trust in superiors. In addition, trust in superiors negatively affects in-role performance and positively affects extra-role performance. Keywords: Transformational Leadership, Transactional Leadership, In-role Performance, Extra-role Performance, and Trust in Superiors.
PROFESSIONAL COMMITMENT AND AUDITOR EXPERIENCES ON AUDITORS’S BEHAVIOR IN AN AUDIT CONFLICT SITUATION AND IMPACT ON THE IMPLEMENTATION OF AUDITORS PROFESSION ETHICS
Authors: Nurwulan Liza Laila , Nissa Fasha Nadya Cipta
Published: July 2018

This study attempts to assess the impact of professional commitment, experience of the audit, the auditors behavior conflict and ethicts audit profession senior auditors on the auditors and colleagues who worked on the public accountant in Bandung. The research population auditors who worked on the public accountant in Bandung, a total of 24 samples Obtained by purposive sampling method. The research using analysis lane. The results of the testing of hypotheses shows that the commitment of professional and experience the audit for the application of auditors of ethical behavior, professional and audit experience the audit for the application of auditors ethical behavior of professionals through auditors the audit of conflict Obtained by the determination of the 73, 8%. Testing professional commitment and auditing experience is a significant relation. To Significantly Affect not commit professional auditors to conduct the audit of conflict. Experience of audit there are significant impact on the behavior of auditors auditing conflict. For testing of professional commitment, there are significant impact on the audit professional ethics. Experience of audit there are significant impact on the audit professional ethics. Behavior auditors and the audit there are significant impact on the application of professional ethics of auditors.
Uluslararası Muhasebe Eğitimi Standartları Kapsamında Muhasebe Eğitiminin Türkiye’deki Akademisyenler ve Muhasebe Meslek Mensupları Açısından İncelenmesi
Authors: TOSUNOĞLU Büşra , CENGİZ Selim , ANADOLU Zafer
Published: July 2018

Bu çalışmanın amacı, uluslararası muhasebe eğitimi standartları kapsamında muhasebe eğitiminin akademisyenler ve muhasebe meslek mensupları açısından incelenmesini içermektedir. Bu doğrultuda üç hipotez oluşturulmuş ve Trabzon İl’inde faaliyet gösteren muhasebe meslek mensuplarına ve Türkiye’de muhasebe eğitimi veren akademisyenlere bir anket uygulanmıştır. Oluşturulan hipotezlerin test edilmesinde bağımsız örneklem t testi kullanılmıştır. Analiz bulgularına göre;  akademisyenlerin ve muhasebe meslek mensuplarının muhasebe eğitimiyle ilgili farklı düşüncelere sahip olduğu söylenebilmektedir. Akademisyenlere göre muhasebe eğitiminde bilgi önemliyken muhasebe meslek mensuplarına göre ise yetenek ve tutumun önemi daha yüksektir.
Türkiye’de Kamu Kesimi Kaynak Tahsisinde Etkinliğin Sağlanması Amacıyla Mali Alan Oluşturma Çabaları
Authors: GÜLŞEN Mustafa Alpin , ÇİÇEK Uğur
Published: July 2018

Günümüzde kamu kesiminin artan sorumlulukları, kamusal
finansmana ilişkin önerilerin ortaya konulmasını zorunlu kılmaktadır. Bu
önerilerin başında gelen mali alan, bir ülkenin makroekonomik planlarına uygun
olarak mali sürdürülebilirliklerine zarar vermeden finansal kaynak yaratma
kapasitesini ifade etmektedir. Çalışmada kamu kaynak tahsisinde etkinliğin
sağlanması amacıyla mali alan oluşturma çabasının Türkiye’de kamu kesimi
açısından önemi ve reel politika oluşturma sürecindeki uyumu vurgulanmaktadır.
Çalışmanın amacı mali alan kavramının açıklanması, uluslararası kuruluşların
mali alan oluşturma konusundaki önerilerinin belirtilmesidir. Çalışmada, Türkiye’de
mali alanın oluşturulması sonrasında elde edilen kaynakların ne şekilde
kullanıldığı konusunda genel bir değerlendirme yapılmaktadır. Buna göre
özellikle faiz harcamalarının azaltılıp mali alan oluşturulduğu görülmektedir.
El método biográfico narrativo aplicado a los bienes culturales. Una experiencia inclusiva e intercultural en la GAMeC.
Authors: Fernández-Inglés Soledad , Gutiérrez-Pérez Rosario
Published: July 2018

La narración no es solo un género literario: se encuentra en la Paleontología, la Historia, la Psicología, la Pedagogía, en el Derecho, en el discurso científico. Es algo verdaderamente amplio. Ciencia y Arte han cooperado en la experimentación del discurso narrativo sobre qué supone narrar, el lenguaje y la percepción en la capacidad de transformar y transformarse del ser humano.

  La narrativa museal está entrando de lleno en algunos museos como medio de acercamiento a la obra de arte. Con detractores y defensores se abre camino de forma tímida, aunque aún no sabemos qué recorrido tendrá en el tiempo. En este ámbito trabaja desde 2007 la Galleria d’Arte Moderna e Contemporanea (GAMeC) de Bergamo, que lo ha adaptado como herramienta de los Servicios Educativos en su política de desarrollo y de inclusión social y cultural.
0+
Authors: Fernandez Lopez Eufemio
Published: July 2018

TITULO: 0+ RESUMEN. Este ensayo performativo es una acción grabada en la intimidad. Se trata de una performance critica con la obtención de un producto artístico final. Consta de 4 partes y un epílogo donde se explica la percepción del ensayo, las críticas sociales a las que hago referencia y la idea de este proyecto. Un proyecto que habla de las injusticias en el mundo del diseño y del arte. ABSTRACT. This performative essay is an action recorded in privacy. It is a critical performance with the obtaining of a final artistic product. It has 4 parts and an epilogue. Here is explained the perception of the essay, the social criticisms to which I refer and the idea of this project. A project that talks about injustices in the world of design and art. PALABRAS CLAVE: performance, sangre, critica, diseño, moda.KEYWORDS: performance, blood, criticism, design, fashion.
La creación artística danzaria: una experiencia de investigación interdisciplinaria / Artistic dance creation: one experience of interdisciplinary research
Authors: Valladares González María Guadalupe
Published: July 2018

En este trabajo se parte de la caracterización de las relaciones que se establecen entre la investigación y la creación artística. La finalidad es contribuir a la visibilización de los procesos de creación propios de las prácticas artísticas de la danza, como forma de investigación artística y de producción de conocimientos, circulantes en la Universidad de las Artes.La investigación artística no se ordena linealmente en proceso y resultado; es parte y todo de una dinámica que está atravesando y siendo atravesada por el proceso de creación, es mediadora y mediada; es en sí misma, inter y transdisciplinar. Es preciso tenerla en cuenta desde la dinámica de su funcionamiento, de su propia práctica. Esta se re-produce, re-formula, según las demandas que la propia acción creativa exige. Es por eso que se despoja del “pre-juicio” para transformarse en performática. La práctica danzaria resignifica al conocimiento artístico en el proceso de creación. De manera que más que reproducirlo, se torna estimuladora de sujetos creativos, productores de conocimientos acerca de la danza, en su gestión artística – investigativa-profesional.
Prácticas artísticas con software libre: taller arte generativo y alimentos
Authors: Oliva Lozano Mónica , Torroja Fungairiño Yago
Published: July 2018

En 2015, los días 10, 17 y 20 de enero se realizó en las instalaciones de la Fundación Telefónica y de la Facultad de Bellas de Artes de la Universidad Complutense de Madrid, el taller Arte Generativo y alimentos: diseñando su tejido con Processing. El objetivo era extraer algunos de los patrones que se dan en los alimentos y en la naturaleza para generar imágenes mediante el uso de Processing, un lenguaje de programación en un entorno de desarrollo integrado que sirve habitualmente para el desarrollo de proyectos multimedia, inserto en la tecnología del software libre. El resultado, estructuras de repetición que generan un patrón, fue luego estampado en tela mediante técnicas permeográficas. El artículo tiene como objetivo mostrar los procesos de creación en la práctica artística, a través de un taller innovador por el contexto expositivo donde se realizó. La práctica puso de manifiesto cómo la creatividad dentro de un ámbito de vanguardia como ha sido la alta cocina del chef Ferran Adrià, debe adaptarse a la realidad cambiante y al desarrollo de nuevas tecnologías. En todo proceso creativo las habilidades tecnológicas específicas se combinan con las capacidades expresivas del artista. Para ello se utilizó como herramienta de creación el programa de código abierto Proccesing, cuyo avance creciente dentro de las iniciativas de software libre se hace cada día más evidente en la práctica artística y en la investigación docente.
Os benefícios do brincar para a saúde das crianças: uma revisão sistemática
Authors: Gomes Nayra Rejane Rolim , Maia Ednei Costa , Varga István Van Deursen
Published: July 2018

Introdução: A definição do brincar é complexa e não háconsenso a este respeito. O brincar permite um desenvolvimentosaudável das crianças e, naturalmente, prepara-as para enfrentaros desafios da idade adulta. Apesar da valorização em saúdepública, revisões sistemáticas que resumam os diferentesachados sobre o brincar ainda são raras. Objetivos: Este estudotem como objetivo rever a literatura recente sobre o brincare resumir seus efeitos positivos sobre saúde das crianças.Material e Métodos: Esta revisão sistemática foi desenvolvidaatravés de busca por artigos publicados nos idiomas portuguêsou inglês, entre 2006 e 2016, nas bases de dados ElsevierScopus, Medical Literature Analysis and Retrieval SystemOnline, Latin American and Caribbean Health SciencesLiterature e Scientific Electronic Library Online. Resultados:A estratégia de busca identificou 12 artigos que atendiamaos critérios de elegibilidade: seis estudos qualitativos, trêsrevisões narrativas, uma revisão sistemática, um estudoquantitativo e um estudo quali-quantitativo. Conclusão: Osdados apresentados reforçam que o brincar é extremamenteimportante para a saúde das crianças. Os benefícios do brincarvão além de contribuir para um adequando crescimentobiológico e desenvolvimento das crianças. Brincar influenciapositivamente o desenvolvimento mental e social, bem comocontribui para uma boa saúde psicossocial. Nos dias de hoje, otempo reduzido para brincar priva as crianças de experiênciasfundamentais para seu desenvolvimento social, afetivo,criatividade e bem-estar. Possivelmente, essa privação nainfância terá efeitos na idade adulta.
Avaliação da qualidade de vida em pacientes com estomia intestinal
Authors: Faria Fernanda Leão de , Labre Mariana Machado , Sousa Ivone Félix de , Almeida Rogério José de
Published: July 2018

Introdução: A estomia intestinal é uma condição que podeafetar a vida das pessoas, seu convívio em sociedade, bemcomo ter consequências diretas para a qualidade de vida.Objetivo: Avaliar a qualidade de vida de pacientes com estomiaintestinal atendidos em ambulatório de um hospital. Casuísticae Métodos: Estudo transversal analítico e quantitativo. Aamostra foi composta por 54 pacientes estomizados, acima de18 anos e acompanhados há pelo menos um ano no ambulatóriode estomia de um hospital de Goiânia/GO. Foram aplicadosum questionário sociodemográfico e a versão abreviada doinstrumento de avaliação de qualidade de vida da OrganizaçãoMundial da Saúde World Health Organization instrument toevaluate quality of life (WHOQOL-BREF). Foi confeccionadoum banco de dados utilizando o SPSS 18. Foi realizada umaanálise descritiva das variáveis e foram utilizados o teste t deStudent e o teste de análise de variância (ANOVA) Scheffépara avaliar a existência ou não de diferença estatisticamentesignificativa (p≤0,05). Resultados: A pesquisa incluiu 54pacientes, sendo 30 do sexo feminino e 24 do sexo masculino.Quanto à renda familiar, 61,1% informaram receber até umsalário mínimo. A maioria afirmou não ter atividades de lazer(62,9%), não praticar atividade física (85,2%) e não estarempregada (92,6%). A média do escore geral da qualidade devida foi 3,7±0,5. Os domínios apresentaram escores indicandoboa qualidade de vida. Identificou-se que não ter religião,ter filhos e maior renda são preditores relacionados a ummelhor escore no domínio meio ambiente. Os que referirammelhor autoavaliação da qualidade de vida também tiverammelhores escores em satisfação com a saúde e domínios físicoe psicológico. Conclusão: Os pacientes com estomia intestinalapresentaram boa qualidade de vida, com menores escoresem meio ambiente, que se relacionam com as facetas dinheiroe lazer. Melhor autopercepção da qualidade de vida indicamelhor satisfação com a saúde em geral.
Learning to Read in Primary School Children with ASD and Intellectual Disabilities at the «Reading and Speech Development» Class
Authors: Tilkhonova K.A.
Published: July 2018

Children with autism and intellectual disabilities are able to master the reading skill in the conditions of systematic
prolonged and adaptive learning. A teacher who realizes present task is important to know and take
into account not only actual, but also potential mental abilities of the student. It is important for the teacher
to apply new techniques of correctional pedagogy in his work, supplementing them with classical evidencedbased
and reliable ones with the reliance on the zone of proximal development and on the principles of special
pedagogy, in particular: developing education, accessibility, visibility, systemic and individuality. It is important
for a teacher to remember that he is not only teaches, but also forming the personality of the child as a
whole. The experience of teaching children with autism spectrum disorders and moderate intellectual disabilities
to read who are educating in the school of the Federal Resource Center for Organization of Comprehensive
Support to Children with Autism Spectrum Disorders is described.
Disinformation in social networks: current state and perspective research directions
Authors: Mikheev E.A. , Nestik T.A.
Published: July 2018

Studying problem of disinformation psychology mechanisms (manipulation of in- formation process), including developing in social psychology way — psychology ma- nipulation in social and mass media. Pay attention such psychology effects as mo- tivated reasoning, that confirms preexisting beliefs, normative influence, homophily, polarization (echo-cameras), negative collective emotions. There are not only theoreti- cal discussion, but also Russian and foreigner psychology, sociology, politology, PR and marketing researches. The ways for counteracting online astroturfing are discussed. Also there are still many psychological factors to be clarified with regard enhanced informal-psychology protection identity, such as, connection between attitude toward disinformation and values, trust, anxiety, social identities and level of social capital.
Trust as a factor of psychological security in interethnic interaction
Authors: Dontsov A.I. , Perelygina E.B. , Zotova O.Y. , Mostikov S.V.
Published: July 2018

The direction and role of trust as a factor of psychological security in social interac- tion is the subject of research attention of Russian and foreign scientists. Confidence appears as a generalized socio-psychological phenomenon, conditioned by the history and experience of previous interpersonal and socio-institutional interactions, features of national cultures and traditions, moral norms and values, attitudes and stereotypes. In the interethnic interaction, a large share in the content of trust relations acquires the experience of interethnic relations, ethno-cultural competence, the lack of intragroup and inter-group aggression, the unity of vectors and perceptions of the security of indi- vidual. To identify indicators of a sense of security, a study was conducted comparing respondents’ perception (N = 514) of themselves in danger, in safety and in an actual state. Factorial-analytical processing allowed to reveal the structure of the personal safety of respondents, where as the significant are five factors. The leading factor (explained variance of 25.653%) is trust, which gives grounds to consider the possibil- ity of providing trust as one of the main indicators of psychological security. Studies conducted in polyethnic groups of students also showed that the phenomenon of trust is an important factor in their psychological security.
Representations of justice of parents as factor of moral development of teenagers
Authors: Avdulova T.P. , Ukhanova D.P.
Published: July 2018

Interrelations between representations of parents of justice and features of moral development of the senior teenagers are investigated. The statistical analysis of interrelation between representations of parents and teenagers of justice where positive correlations concerning level of indicators of sensitivity to justice from four positions are found (the victim, the perpetrator, the observer and the beneficiary) is submitted. Positive significant interrelation between the level of conscience of teenagers and fathers are shown; between components of style of education of parents and indicators of sensitivity to justice of teenagers and also representations of teenagers of style of education of their parents. In style of education of parents the most significant were following components: level of a patronage, requirements, satisfactions of needs and projection of children’s qualities to the teenager. Differences in influence of an educational position of mothers and fathers on sensitivity to justice are found in teenagers, in particular negative impact of a maternal infantilization.
FARKLILIKLARIN YÖNETİMİNİN ÖRGÜT KÜLTÜRÜNE OLAN ETKİSİ: İSTANBUL’DA FAALİYET GÖSTEREN HİZMET SEKTÖRÜNDEKİ ÇALIŞANLAR ÜZERİNDE BİR ARAŞTIRMA
Authors: AKAN Merve , KANIK İlkay
Published: July 2018

Günümüzde yaşanılan teknolojik gelişmeler ve
küresel rekabetin artışıyla birlikte örgütlerin, rakiplerine karşı rekabet
avantajı sağlama istekleri de artış göstermektedir. Örgütlerin birbirlerine
karşı rekabet avantajı sağlarken, farklılıkların yönetimi uygulamalarını
kullanmaları örgütlerin bu anlamdaki işlerini kolaylaştırmaktadır. Farklı
özelliklere sahip insanların bir arada çalışması hem örgüte faydalı olmakta hem
de örgüt kültürünün bu farklılıklar doğrultusunda oluşmasını sağlamaktadır.
Farklılıkların doğru yönetilmesi örgüt kültürünün tüm çalışanlar tarafından da
kabul edilmesini sağlamaktadır. Farklılıkların yönetimi ve örgüt kültürünün
ilişkisinin daha iyi anlaşılması için bu çalışmada İstanbul bölgesindeki hizmet
sektöründe farklı alanlarda faaliyet gösteren bireylerin farklılıkların
yönetimine ve örgüt kültürüne yönelik algılarını ölçmek için, 191 çalışan ile
anket çalışması yapılmıştır. Bu araştırma sonucunda, çalışanların farklılık
algılamalarının örgüt kültürü hakkındaki algılamalarını etkilediği saptanarak
çalışmanın hipotezi kısmen doğrulanmıştır. Araştırmanın amacı; örgütlerdeki
farklılıkların yönetimi uygulamalarının örgüt kültüründe etkili bir şekilde
kullanılabileceğini inceleyerek, ölçümlemektir.
Evaluation of a new technique for abdominal wall closure in midline laparotomies
Authors: Mohamed Abd El Shahid Moharam Abdelsamie , Mahmoud Fawzy Abo Bakre , Elmallah Said Ebrahim
Published: July 2018

Background: An efficient technique for abdominal wall closure should provide strength and be a barrier against infection. Method of closure and type of suture material are critical aspects of an effective abdominal wall closure after midline laparotomy. Dehiscence of abdominal wounds after closure is a serious complication especially in emergency laparotomies. Our study was done to know whether our method of abdominal closure was helpful in reducing incidence of wound dehiscence.Methods: Present study was carried out as a retrospective randomized clinical study in the department of general surgery, Menoufia University Hospitals for one year starting from March 2017 to March 2018. 168 patients had midline laparotomies (either elective or emergent) for inflammatory, traumatic or neoplastic indications.Results: In present study for this new technique of abdominal wall closure after midline laparotomies, wound infection was noticed in 12/168 (7.2%) cases and 2/168 (1.2%) patients developed wound dehiscence.Conclusions: Present study demonstrates that our new technique (Moharam Repair) of abdominal wall closure after midline laparotomies) is efficient in reducing post-operative wound dehiscence (burst abdomen). So, this technique is applicable, safe, and can minimize morbidities and mortalities related to wound dehiscence (as a short-term complication) after midline exploratory laparotomies (MEL).
Laparoscopic versus open restoration of the gut continuity after Hartmann’s procedure
Authors: Ahmed Ahmed E. , Ahmed Wael B. , Redwan Alaa A.
Published: July 2018

Background: In 1921, Hartmann, a French surgeon described his operation for the resection of left-sided colonic carcinoma. The technique described a sigmoid colectomy without anastomosis; a left lower quadrant end colostomy and the rectal stump closure was performed. The aim of this study was to compare the outcome of the laparoscopic and open restoration of the gut continuity after Hartmann operation as regard operative and post-operative complication.Methods: All patients who underwent restoration of the gut continuity after Hartmann’s procedure either laparoscopic Hartmann’s closure or open Hartmann’s reversal between December 2013 and December 2016 were included.Results: Between December 2013 and December 2016, 32 patients underwent restoration of the gut continuity after Hartmann’s procedure in Sohag university hospitals, Egypt, were enrolled in this study.14 patients had a laparoscopic reversal of Hartmann’s colostomy and 18 had an open reversal of Hartmann’s colostomy. There was no significant difference between both groups as regard age, sex, body mass index, length of remaining rectal stump or time interval between primary operation and Hartmann reversal. The most common indication for Hartmann’s colostomy was obstructed recto sigmoid cancer (13/32). The operative time was significantly shorter in LHR group (107 minutes versus 124 minutes p=0.031), time to pass flatus was significantly earlier in LHR (1.70 days versus 3.33 days p=0.000) , wound complications were significantly lower in LHR (1 case versus 8 cases p= 0.044), LHR had less post-operative pain 24 hours after procedure (VAS was 5.93 versus 8.72 p= 0.000).The length of hospital stay was significantly shorter in the LHR group (6.55 days versus 12.14 days P = 0.038), no significant difference between both group as regard intraoperative complications, leakage, reoperation or postoperative complications. Moreover, no mortality was detected in this study.Conclusions: Laparoscopic reversal of Hartmann’s operation is safe as open surgery, and had less postoperative pain, wound infection and shorter hospital stay. It should be the procedure of choice for reversal of Hartmann’s operation.
Desarda versus Lichtenstein repair for inguinal hernia: a randomized, multi-center controlled trial with promising results
Authors: Ahmed Ahmed E. , Ahmed Wael B. , Omar Mohammad Ahmad , Redwan Alaa Ahmad
Published: July 2018

Background: The techniques for treatment of an inguinal hernia range from the tissue-repairs to the tension-free hernioplasty. The use of a mesh for repair not free of complications and had higher costs. The Desarda technique for inguinal hernia repair is a new tissue-based method application of the external oblique muscle aponeurosis in the form of an undetached strip has been introduced as a new concept in tissue based hernia repair. The aim of the present stusy was to compare the standard mesh-based Lichtenstein technique with the tissue-based Desarda technique.Methods: In this prospective study, patients with an Inguinal hernia who were referred and enrolled in the study for elective Desarda or Lichtenstein repair between May 2012 and November 2016 at Sohag and Assiut university hospitals, Egypt; Operation, anaesthesia, rescue analgesia and postoperative care were standardized. Patients were assessed for operation time, postoperative pain, hospital stay, foreign body sensation, complications and recurrence rate in the postoperative period on day 1, 1 week, 1, 12 and 24 months, postoperatively.Results: Of 130 patients were included in the study, 65 underwent Desarda (D) versus 65 underwent Lichtenstein repair (L) between May 2012 and November 2016 at Sohag and Assiut university hospital in Egypt. In Desserda group (D) 64 OF 65 patients were male and in Lichtenstein repair group (L) 65 of 65 were male. The patient's age for (L) Group was 40±11.69 and for (D) group was 38±11.55. As regards operative time, hospital stay, return to activity and work for or post-operative pain 24 hours and 7 days after the operation. D group was significantly lower than (L). No difference between groups regarding intraoperative, postoperative complication, mortality rate, recurrence rate, or post-operative pain six months after operation.Conclusions: Desarda repair had lower operative time, early return to basic and work activity, shorter hospital stay and less post-operative pain than Lichtenstein repair. The result of our study supports the use of Desarda repair in our hospitals as the method of choice for most of the patients due to low cost, low recurrence rate, and simplicity of repair.
Study of early post-operative complications in relation to nature of anaesthesia and type of surgery
Authors: Qureshi Irfan Parvez , Qureshi Saima , Modi Vimal
Published: July 2018

Background: Many people have complications after surgery; some transient, others serious, but all are important to patients. The likelihood of postoperative complications is influenced by the type of surgery, the patients pre-existing comorbid state and perioperative management. Anaesthesia result in a variety of metabolic and endocrine responses, but conventional wisdom maintains that anaesthetic technique has little long-term effect on patient outcomes. There is accumulating evidence that, on contrary, anaesthetic management may in fact exert a number of longer-term effects in postoperative outcome.Methods: A prospective study of early post-operative complication in 100 patients’, who underwent major surgery, was done in the Department of Surgery in a tertiary care teaching hospital, Indore. Therefore, the present study was carried out prospectively to study the incidence of postoperative complications in relation to age, sex and other factors which influence them and correlation of post-operative complications with the nature of anaesthesia, duration of operation, type of surgery and in surgery above diaphragm or below diaphragm.Results: The incidence of post-operative complications was more in patients operated with general anaesthesia (48.38% and 12.9% respectively) the morbidity and mortality in patients who were operated under spinal anaesthesia was lower than general anaesthesia, but morbidity was higher in patients who were operated under epidural anaesthesia, but mortality was lower than epidural.Conclusions: There is accumulating evidence that anaesthetic management may indeed exert a number of influences on longer term postoperative outcomes. Further prospective, randomized, large scale, human trials with long- term follow-up are required to clarify the association between anaesthesia technique and postoperative outcome.
A comparative study of pyeloplasty in children with and without stenting
Authors: Jadhav Pranav , Hegde Adarsh , Vaze Dhananjay
Published: July 2018

Background: PUJ obstruction is the most common among the major obstructive pathologies in pediatric patients. The study aims to compare the benefits and drawbacks of stentless pyeloplasty in pediatric population with routine DJ stent insertion.Methods: Data was collected for operated cases of PUJ obstruction and categorised into those who had DJ stent in situ and those without DJ stent. Complications associated with both these approaches was systematically assessed.Results: In patients with DJ stent in situ the perinephric drain was minimal and hence most of the patients had their drain removed on the 2nd or 3rd day. In those patients without DJ stent in situ, the average duration for removal of drain was prolonged to about 7 days.Conclusions: Routine use of Ureteric stenting with DJ stent in this series of patients was associated with decreased hospital stay and morbidity in patients without DJ stent.
T-shaped Meckel’s diverticulum: a rare anatomical variant complicating small bowel volvulus
Authors: Paul Vergis , R. Ramu , Mathews Kocheril Sheryl , Thomas Ashly , P. A. Reesha , Matthai Anna , Kurup Sandhya
Published: July 2018

The Meckel's diverticulum is a congenital diverticulum arising from the terminal ileum and is the unobliterated proximal portion of the vitellointestinal duct. Intestinal obstruction due to Meckel’s diverticulum is the most common presentation in adults and is the second most common presentation in children. We present a case of a 58-year-old gentleman presented with acute abdomen who was later found to have Giant T- shaped Meckel’s Diverticulum complicating small bowel volvulus on exploratory laparotomy. A T-shaped Meckel's diverticulum has not yet been described.
A quasi-experimental study evaluating a health promotion program targeting healthy nutrition, physical activity and social network enhancement for low-income multi-problem households: study protocol
Authors: Abidi Latifa , Nagelhout Gera E. , Spruijt Renate , Schutte Hermijn , De Vries Hein
Published: July 2018

Background: Previous studies have shown that people living in multi-problem households are less physically active, eat less healthy, have unstable social networks, and worse self-perceived general health than other people. The aim of this paper is to describe the development and evaluation of a health promotion program called “Back2Balance” for low-income multi-problem households aimed at improving healthy nutrition, physical activity, social networks, and self-perceived health.

Methods: The Back2Balance program was developed using input from two formative studies and a co-creation process together with the target group and social workers. We used the theoretical domains framework to identify the functional components of our program. The Back2Balance program consists of: 1) a walking group, 2) cooking workshops, 3) motivational talks, 4) discounts on existing health promotion programs, and 5) family trips and children’s activities. In a quasi-experimental study respondents in the intervention group receive the usual social services support for multi-problem households and have the possibility to enroll in the program. Respondents in the control group only receive usual social services support. The program will be evaluated among 272 respondents from low-income multi-problem households living in Apeldoorn, the Netherlands.

Conclusions: This protocol describes the development and evaluation of the Back2Balance program. We hypothesize that the program will lead to increased physical activity, healthy nutrition, social networks enhancement, and self-perceived health. The results of this study can be used as input for other national or international initiatives aiming to increase health of low-income multi-problem households.

Trial registration: NTR6512

 
Clinical trial of combination therapy for the efficacy, safety, tolerability and improvements in quality of life in patients with moderate to severe plaque psoriasis
Authors: G. V. Amruthavalli , V. Aruna , R. Gayathri
Published: July 2018

Background: Psoriasis is an autoimmune disorder with clinical manifestations scales, inflammation and dryness. The psoriatic skin behaves differently in concurrence with circadian rhythm. Cell division increases in late night and early morning hours. Enzymatic activity will be more during day time. To balance these variations a 24×7 protection is required. The objective of the present study is to find the improvement in Psoriasis condition with the Combination therapy compared to single drug usage.

Methods: A clinical trial for 4 weeks was conducted among psoriasis patients with psorolin oil vs. combination therapy (Dr. JRK’s 777 oil, psorolin ointment, psorolin oil and psorolin medicated bathing bar) and the clinical relief was measured among both groups by following parameters like psoriasis area and severity index (PASI), Physician’s global assessment (PGA), dermatology life quality index (DLQI), subjective self-assessment questionnaire (SSAQ) and subject investigational product feedback questionnaire (SIPFBQ).

Results: Combination therapy (1-3-2 topical therapy) of Dr. JRK’s 777 oil, psorolin ointment, psorolin oil and psorolin medicated bathing bar as a treatment regimen was found to be more effective in the treatment of psoriasis.

Conclusions: 1-3-2 topical therapy is useful in severe psoriasis conditions and recommended for long term effective treatment of psoriasis.

 