bluuebunny/crossref_metadata_2025 huggingface dataset:
Better Option for Improving Metabolic Syndrome: Consideration of the Amount and Duration of Resistance Exercise or Physical Activity
Authors: Jo Hyeon-Deok , Kim Maeng-Kyu
Published: June 2023

PURPOSE: Physical activity (PA) improves the metabolic syndrome (MetS) risk. According to a recent revision of the PA guidelines for Americans (2018), healthy adults should participate in PA for >300 min/week for additional health benefits. In addition, it is recommended to participate in resistance exercise (RE) ≥2 days/week. This study aimed to determine whether increasing the PA duration or adding RE is more efficient in improving MetS.METHODS: Data from the 2016-2018 Korean National Health and Nutrition Examination Survey were used. The logistic regression and general linear models in the complex sample were performed with a sample of 8,662 Korean adults aged 19–65. According to the metabolic equivalent task (MET), PA intensity was categorized as low-(LP; <600 MET-min/week), moderate-(MP; 600-3,000 METmin/week), and high-level PA (HP;≥3,000 MET-min/week). Furthermore, duration was categorized as high duration (HD) and low duration (LD), while RE was categorized more 2 days/week RE (MR) and less 2 days/week RE (LR).RESULTS: Compared with LP-LR the MR groups showed a significantly low odds ratio (OR) of MetS (p<.05 respectively), whereas the LR groups had no significant OR (p>.05 respectively). Compared with LP-LD, HP-HD had significantly low OR (p<.05), whereas other groups had no significant OR (p>.05 respectively).CONCLUSIONS: Frequent RE decreases the OR of MetS and is not dependent on PA intensity. To efficiently reduce the OR of MetS in Korean adults, participating in frequent RE, rather than simply prolonging PA, is recommended; although, increasing PA duration can have positive effect in HP. In terms of the reduction of the MetS, more than 300 min/week of PA is unlikely to achieve additional health benefits.
Mulheres na Polícia Militar: História, cultura e desafios futuros
Authors: Lopes Rebeca da Silva Brito , Oliveira Maria Cláudia Santos Lopes de , Jorge Gabriel de Oliveira
Published: June 2023

O ingresso da mulher em espaços ocupados predominantemente por homens tem aumentado nas últimas décadas, inclusive na política, ciências e instituições. Esse movimento resulta de transformações sociais, culturais e políticas. Nesse sentido, este artigo apresenta a trajetória da mulher na profissão policial militar, espaço icônico da ausência feminina, a partir da reflexão sobre a importância da cultura na constituição dos sujeitos. Ao mesmo tempo, este estudo reflete sobre a inclusão feminina nas polícias militares e seus desdobramentos em suas constituições históricas. Além disso, busca-se compreensão sobre desigualdades reproduzidas e justificadas ao longo da história dessas instituições. Implicações, limitações e direções futuras são apresentadas e discutidas.
Strategy of transition to a new world economic order and noosociety: industrial aspect
Authors: Bodrunov S. D.
Published: June 2023

Contemporary transformation of the economic and social system requires changes in approach to its analysis and in management of its development. At the same time, in the author’s opinion, there is no need to keep the traditional approach based on the neoliberal theory and methodology. For Russia, the Chinese experience is more suitable, based on the dosed and proportional combination of elements of market-based and planned models of economy management. It is precisely this approach that delivers sustainable technological, economic and social development, in process of which the tasks of qualitative renewal of all fields of public life are solved. And in addition, the central focus is made in the development of high-tech industries, which are becoming a core of an economic and social system being renewed. This requires top-priority development of fundamental science, culture and education, as well as the return of the state into capitalist process, to the direct public administration of a number of development spheres, active support of state and public-private high-tech corporations. The basis of the development is technological advance. It also changes in new conditions. A new quality of industrialized production is observed. It is knowledge-intensive production, for which not only a speed-up is typical, but also a speed-up of speed-up of technological development. Today, Russia solves tasks not only in industrialization or reindustrialization: such tasks will be mostly solved anytime soon; but also is facing the task of creating the basis of the new industrial society of the second generation (NIS.2), a society where knowledge takes the leading role. The latter means the priority of knowledge-intense production united with science and education. Hence, a necessity arises to integrate those three spheres within the frame of united reproduction contour on all levels: mirco-, meso- and macroeconomics. To solve this task, an active industrial policy and strategic planning are essential, together with the activity of private funds and orientation to social interests of public sector. Author has explored and elaborately describes in details a toolset necessary for that in the article.
The mind-body problem and the irrationality of the brain’s phenomenal judgements
Authors: Isaev Maxim M.
Published: June 2023

The article gives a brief overview of the problems faced by materialism in connection with the phenomenon of consciousness. Yet new arguments help to uncover the problems of alternative positions to materialism, above all, the dualism of properties. Key arguments show that it is difficult for non-physical consciousness to perceive its own nature even when it has direct access to experience. That is due to the fact that the physical substratum of consciousness implements a self-sufficient physical intelligence. And if that intelligence ceases to conclude that consciousness is non-physical, which would be unreasonable to it, then non-physical consciousness, despite any arguments it has had, inevitably comes to the wrong conclusion for itself that it is not non-physical. It turns out that consciousness requires such a study to know its nature, which paradoxically comes to the truth only in the error of the physical intelligence, with the latter constituting the intellectual faculties by which such inquiry is made. Such a need for error is difficult to justify. Likewise, by similar logic, it is impossible to prove flawlessly the existence of non-physical consciousness. If it existed, an individual with a perfect intelligence and direct, non-physical access to consciousness would come to a corresponding anti-physicalist conclusion on its basis. But such an outcome cannot happen, since this conclusion depends on an equally perfect and error-free physical intelligence, for which it is not true. Thus, we are deprived of sufficient justification to conclude that our consciousness is non physical. At the end, a path to finding a solution to the problem of consciousness is briefly outlined, providing a way out of a situation where there is such a strong critique for all positions in the philosophy of consciousness. It is related to an exploration of the nature of our antiphysicalist ideas.
The Review of the monograph by V.T. Faritov “Nietzschean reflections. Essays on the philosophy of marginality” St. Petersburg: Aleteya, 2022
Authors: Fatenkov Alexey N.
Published: June 2023

The monograph of Vyacheslav Tavisovich Faritov, Doctor of Philosophy, Professor of the Department of Philosophy and Social and Humanitarian Sciences of Samara State Technical University, Nietzschean Reflections. Essays on the Philosophy of Marginality, published in 2022.
The influence of neural networks on the formation of media reality
Authors: Romadanova Svetlana V. , Mukhametshina Natalya S.
Published: June 2023

With the development of information technology, there are both new opportunities and challenges. Media generated by a neural network is becoming one of the most relevant trends of the present time. As the capabilities of the neural network increase, the question of how the media reality is formed under these conditions becomes more and more relevant. The article deals with the problem of the influence of neural networks on reality.
Peritoneal pseudocyst: a rare complication of peritoneal dialysis
Authors: Sarabia-Pérez Yoselin Julisa , Heredia-Montaño Mónica , Vela- Ramos Montserrath Ashanti , Díaz-Barrientos Cheryl Zilahy , Sosa-Sánchez Omar , Zayas-Borquez Rogelio
Published: June 2023

Peritoneal dialysis is a method of renal function replacement which has a series of advantages like greater autonomy of the patient, but it also has disadvantages, like leakage, peritonitis and abdominal wall weakness. We present the case of a patient with a history of renal replacement therapy managed on peritoneal dialysis which presents a rare complication that required surgical treatment. A peritoneal pseudocyst enclosing the dialysis catheter tip is a rare complication of peritoneal dialysis. The pathogenesis of pseudocyst formation is not yet explained; however, bacterial infections and abdominal surgery seem to be predisposing factors. It is important to know how peritoneal dialysis works and the early and late complications of this renal function replacement therapy. Further studies are needed in this area to look into the pathophysiology and evaluate the contributing factors for the development of peritoneal pseudocyst and its treatment.
A histopathological study of ovarian lesions in a rural medical college
Authors: Dhule Sheetal Mahajan , Yasmeen Qureshi Saba , Narkhede Piyush Prakash , Shafee Tooba Fatima Mohammed , Fatema Ishrath
Published: June 2023

Ovarian lesions can present in any age of life and has a wide spectrum of presentation. They contribute to most of the pelvic masses encountered in clinical practice in reproductive age group. Histopathological examination is of prime importance in ovarian lesions as it is difficult to diagnose these lesions on basis of clinical history, radiology alone.

: To analyse the spectrum of ovarian lesions and to categorize them on basis of histomorphological pattern.

A total 132 cases were studied from January 2022 to December 2022. Relevant clinical details and histopathological findings were reviewed and analysed.

A total of 132 cases of ovarian lesions were included in this study with age range from 20 years to 72 years. Non neoplastic cases were 71 and neoplastic cases were 61 in present study. Follicular cyst was the commonest non neoplastic lesion (48 cases) followed by haemorrhagic corpus luteal cyst (16 cases). Out of 61 neoplastic lesions, 56 were benign, 3 were borderline and 2 were malignant on histopathological examination. Mucinous cystadenoma was the commonest benign lesion and serous cystadenocarcinoma was the commonest malignant tumour in the present study. Borderline mucinous cyst adenoma was the commonest in borderline cases in our study. Unilateral presentation of ovarian lesions was found in 116 cases and bilateral in 16 cases.

In present study majority of cases were of non neoplastic lesions. For accurate management of the ovarian lesions it is important to correlate clinical findings and ultrasonography findings with histopathology diagnosis.
Clinico-pathological correlation study in chronic kidney disease patients undergoing hemodialysis
Authors: Kumar M Pavan
Published: June 2023

Chronic Kidney Disease (CKD) is a global health problem and associated with increased morbidity and mortality. Hemodialysis is the most common mode of renal replacement in end stage kidney disease. Variation in hematological and biochemical parameters are the prime factors responsible for morbidity and mortality in CKD patients. Normocytic Normochromic Anemia is a typical morphology seen in CKD patients resulting due to erythropoietin deficiency. Early detection and treatment of these pathologies can improve the quality of life in CKD patients.

: 1) To evaluate the clinical manifestations and various pathological changes associated with CKD patients on hemodialysis. 2) To compare and correlate various clinico-pathological parameters in CKD patients on hemodialysis, with special emphasis on diabetic kidney disease.

: One year eleven months retrospective study was done at CIMS hospital, which included 50 CKD patients. Complete clinical data were recorded and correlated with various hematological and biochemical parameters. Statistical analysis was performed by chi square test and student’s T test.

Out of 50 CKD patients, 86% were male, age group of 41-50 years (62%). The commonest co-morbidity was combined hypertension with diabetes in 44%. Majority (72%) had BP between 140-159mmHg. Most (64%) of the CKD patients were known cases of diabetes. Significantly lower levels of RBC count, hemoglobin, hematocrit and platelet count were found with normocytic normochromic anemia being the commonest morphological type. Significantly increased WBC counts, ESR, serum urea, creatinine and serum phosphate levels were noted in CKD patients. DKD patients showed significant risk compared to NDKD patients.

CKD is a progressive, irreversible disease. We found alterations in various haematological and biochemical parameters, which were more severe among DKD patients compared to NDKD patients. Early recognition and management of these changes will have an important impact in improving the quality of life.
Comparative study of fine needle aspiration cytology and histopathology correlation of various thyroid lesions
Authors: Doifode Dnyaneshwar Ashok , Adhye Amruta Shrinivas , Surase Sanjay Gajanan , Hiwale Buddheshwar Narayan
Published: June 2023

Patients with anterior neck swelling constitute common problems encountered in the clinical practice. In all age groups, including children, thyroid cancer is the most prevalent endocrine system cancer. Initial diagnostic testing using fine needle aspiration cytology (FNAC) has been found to be quick and cost effective. Therefore, it is widely accepted and more thyroid cases are diagnosed at an early stage, but it is associated with pitfalls due to difference in correlations between FNAC and Histopathological Examination (HPE). The purpose of the study is to compare the results of FNAC with histopathological findings in order to evaluate the diagnostic efficacy of FNAC.

The present study was performed over a period of two years in a tertiary care center. Included in the study were 100 cases of thyroid nodule, which underwent FNAC and the post-operative specimens of whom were subjected to histopathological examination. The results obtained by FNAC were compared with histopathological findings.

Out of the 100 cases taken for the purpose of the study, 92 were benign whereas 8 were malignant. The cytological and histopathological diagnosis correlated with each-other in 89 cases. A partial correlation between the cytological and histopathological diagnoses was found in 5 cases. In 6 cases the FNAC diagnosis was not correlating with histopathological diagnosis. FNAC revealed a sensitivity of 62.50%, a specificity of 97.83%, an accuracy of 95%, a positive predictive value of 71.43% and a negative predictive value of 96.77%.

FNAC of thyroid lesions is thus proved to be a simple, cost effective and accurate method to diagnose and to guide the management of palpable thyroid lesions Thus, we can see that the diagnostic accuracy of FNAC procedure is very high making it a very useful investigation in the work-up of thyroid patients. However final diagnosis and treatment pattern should be based upon histopathology.
A comparative study of red cell histogram along with CBC parameters and peripheral blood smear in various anemias
Authors: Dhakar Durgesh Kumar , Rai Naresh N
Published: June 2023

: The red blood cell (RBC) parameters generated by cell counters can aid in morphological categorization of anemia, the significance of microscopic analysis of peripheral blood smears (PBSs) cannot be overlooked when it comes to interpreting the underlying cause of anemia. Therefore, both RBC parameters and microscopic examination of PBSs are essential for a comprehensive assessment of anemia.

This study aimed to evaluate and compare the results obtained through two different methods: examination of peripheral blood smears (PBS) and automated cell counter generated parameters. The objective was to identify any differences or similarities in the diagnostic outcomes produced by each method.

Over the course of one year, from December 2020 to November 2021, a hospital-based, prospective study was conducted. The study aimed to evaluate and compare the PBS findings and RBC parameters and histograms generated by a cell counter in 1000 anemic patients.

In a sample of 1000 cases, we compared the typing of anemia using an automated analyzer and peripheral smear examination. Out of these cases, 690 showed consistent typing results between the two methods, while 310 showed discordant typing. The automated analyzer diagnosed majority of cases 70.1% as microcytic anemia and Normocytic, dimorphic, and macrocytic cases were found in 13.5%, 7.8%, and 4.3% of cases, respectively. Additionally, a normal histogram was observed in 17.6% of cases.

We have concluded that while the automated analyzer is useful in reducing the overall workload through its graphical representation of anemia typing, it should always be confirmed through microscopy. The automated analyzer is a helpful tool, it should not be relied upon solely for accurate anemia typing. Microscopy remains an essential method for confirming the results of automated analysis.
Ibrutinib induced sensorimotor neuropathy: A novel side effect
Authors: Panda Dipanjan , Tiwari Disha , Sharma Atul , Kishan Dewesh
Published: June 2023

Chemotherapy-induced peripheral neuropathy (CIPN) is a well-documented toxicity leading to dose limitation.

Ibrutinib is an oral Bruton’s Tyrosine Kinase (BTK) inhibitor approved for treating chronic lymphocytic lymphoma. The most common neurological side effects of Ibrutinib include headache and dizziness. Herein, we report peripheral neuropathy as a dose-limiting manifestation of Ibrutinib treatment.
Pleomorphic rhabdomyosarcoma of lumbar region: A case report
Authors: Daniel Blessy , Sudhindra S G , Shankar M
Published: June 2023

Rhabdomyosarcoma is a malignant mesenchymal soft tissue tumour with tendency towards skeletal muscle differentiation. It is commonly seen in children and adolescents but is exceedingly rare in adults. The most common site in adults is the extremities. Less common locations include pelvis and thorax. The tumour is diagnosed by the morphologic presence of scattered pleomorphic rhabdomyoblasts and immunohistochemistry (with evidence of at least one skeletal muscle-specific marker). The outcome of tumour in adults is very poor, especially when compared to outcomes in children in whom significant improvements with treatment have been achieved. We present a case of Pleomorphic Rhabdomyosarcoma at the lumbar region which was clinically thought as a dermoid cyst. This case is reported because of rare location. The diagnosis was made on histopathology and immunohistochemistry. The tumour was diffusely positive for vimentin and desmin and focally positive for myogenin & MyoD1.
Endoscopic resection of gastric calcifying fibrous tumor: An incidental finding
Authors: Chopra Shikha
Published: June 2023

Calcifying fibrous tumor (CFT) is benign mesenchymal lesion. CFTs of the GI tract are quite rare with less than 60 cases of gastric CFTs reported in the English literature. In a healthy 49 old female, routine Endoscopic ultrasonography (EUS) revealed an internally isoechoic, homogeneous 12mm lesion mainly within the submucosa in the distal body of stomach with no significant past history. An endoscopic submucosal dissection (ESD) was done to rule out malignancy. The histopathological examination showed a hypocellular lesion with few spindle cells interspersed in a hyalinized, collagenous matrix with occasional lymphoplasmacytic cells. Foci of psammomatous, dystrophic calcification were noted. Immunohistochemical examination revealed tumor cells positive for vimentin and negative for CD34, CD117, DOG1, desmin, SMA and S100. Based on histopathological and IHC findings, a diagnosis of gastric calcifying fibrous tumour was made. Only a handful of CFT cases resected by endoscopic submucosal dissection has been reported in the literature. So herein we report a rare case of endoscopically resected gastric calcifying fibrous tumor.
Collision tumor of ovary – Case report
Authors: Mukilarasi K R  , Kavita V
Published: June 2023

Collision tumors are rare neoplasms defined by the presence of two distant tumors in the same organ without any histological intermixing. Each component of the collision tumor occur coincidently and no connection is found between the tumors. Our case is a collision tumor of ovary composed of mature cystic teratoma and Mucinous cystadenoma.
Sebaceous cell carcinoma of the scalp in a young male: A rare case report
Authors: Hassan Mohammad Jaseem , Ahmed Saqib , Ahmad Murad , Arif Sayeedul Hasan , Siddiqui Bushra
Published: June 2023

Sebaceous carcinoma is a rare locally aggressive neoplasm of the sebaceous gland, which occurs frequently in elderly males. It constitutes 0.2 to 4.6% of all the malignant cutaneous tumours and occurs commonly in the periocular area. Scalp is a rare site for this tumor. Here we report a case of sebaceous carcinoma in a young 28 years old male patient who presented with firm to hard exophytic growth over right posterior occipital region with enlarged suboccipital and post auricular lymph nodes. Wide local excision was done and a diagnosis of sebaceous carcinoma of the scalp with lymph node metastasis was rendered after histopathological and Immunohistochemical examination.
"SOFT POWER" OF MODERN RUSSIAN CINEMA IN THE CONTEXT OF HYPE POLITICIZATION
Authors: Ezhov Dmitriy А. , Kalinin Daniil М.
Published: June 2023

Aim.To analyse modern Russian cinematography as a tool of "soft power" in the context of creating media hype around its individual products.

Methodology.The study is based on a communicative approach. Methods of observation, traditional analysis of documents and case study were used.

Results.Based on a specific example an actual approach to the perception of the Russian cinema products as tools of "soft power" is demonstrated. It is most significant and indicative in the context of attempts to deny Russian culture against the backdrop of aggravated relations with the United States and European states as a result of Russia's Special Military Operation in the Ukraine.

Research implications.The results of the study can be used in scientific and teaching activities in the course of considering the concept of "soft power" and hype technologies, in the work of political technologists, and specialists in the field of art and culture.
Zeydî-Mu‘tezilî Literatürde Bir Yitiğin Keşfi: İbn Şervîn ve Yâḳūtetü’l-îmân ve Vâsıṭatü’l-Burhân’ı-İnceleme ve Neşir-
Authors: ÇETİN Serkan , KILAVUZ Ulvi Murat
Published: June 2023

Zeydîlik ile Mu‘tezilîlik arasındaki, teşekkül dönemlerine kadar uzandığı da iddia edilen ilişki ve etkileşim, Büveyhî veziri Sâhib b. Abbâd’ın Kādî Abdülcebbâr’ı Rey’e davet etmesi ve kādilkudât olarak atamasıyla birlikte Mu‘tezilîliğin merkezi hâline gelen Rey’de daha güçlü bir evreye geçmiştir. Bu süreçte Taberistan/Hazar Zeydîleri’nden birçok âlim Kādî’den ders alarak onun talebesi olmuştur. Zeydî-Mu‘tezilî kimliği açık olan İbn Şervîn de bu âlimlerden biridir. İbn Şervîn kelâm ve fıkıh alanında önemli eserler telif etmiş ve eserleri Taberistan sınırları içerisinde kalmayarak Yemen Zeydîleri’ne kadar ulaşmıştır. Onun Yemen Zeydîleri’ne kadar ulaşan önemli kelâm eserlerinden birisi de yakın zamana kadar kayıp olarak bilinen ve tarafımızdan keşfedilen bir mecmua içerisinde, önemli bazı diğer Zeydî-Mu‘tezilî eserlerle birlikte bulunan Yâḳūtetü’l-îmân ve vâsıṭatü’l-burhân’ıdır. İbn Şervîn, Zeydî-Mu‘tezilî kelâm metinlerinde zaman zaman kısmen farklı formlarıyla rastlandığı biçimde Yâḳūtetü’l-îmân’ın sistematiğini, i. Tevḥîd, ii. ʿAdl, iii. Vaʿd, iv. Vaʿîd, v. Emr bi’l-maʿrûf, vi. Nehy ʿani’l-münker, vii. Nübüvvet, viii. İmâmet şeklinde sıraladığı dinin sekiz temel ilkesi üzerine kurmuştur. Onun bu metni üzerine VI./XII. yüzyıl Yemen Zeydîleri içerisinde Behşemî kelâm geleneğinin önemli bir temsilcisi olan Hasen b. Muhammed er-Rassâs, et-Tibyân li-Yâḳūteti’l-îmân ve vâsıṭati’l-burhân başlığıyla “Tevhîd” ve “Adl” bölümleriyle sınırlı oldukça kapsamlı bir şerh kaleme almıştır.
Determine phenotypical patterns of resistance to antibiotics in COVID-19 patients with associated bacterial infection: largest medical center in Iran
Authors: Mohammadnejad Esmaeil , Seifi Arash , Gheshlagh Reza Ghanei , Aliramezani Amir , Fattah Ghazi Samrand , Salehi Mohammadreza , Manshadi Seyed Ali Dehghan , Orandi Amirhossein
Published: June 2023

Background and Objectives: Antibacterial resistance (AMR) is a serious threat and major concern, especially in developing countries. Therefore, we aimed to determine phenotypical patterns of resistance to antibiotics in COVID-19 patients with associated bacterial infection in intensive care units.
Materials and Methods: In this cross-sectional study, 6524 COVID-19 patients admitted for more than 48 h in the ICUs of Imam Khomeini Complex Hospital (IKCH) in Tehran from March 2020 to January 2022 were included in the study with initial diagnosis of COVID-19 (PCR test and chest imaging). Data were collected regarding severity of the illness, primary reason for ICU admission, presence of risk factors, presence of infection, length of ICU and hospital stay, microbial type, and antibiotic resistance. In this study, the pattern of antibiotic resistance was determined using the Kirby–Bauer disk diffusion method.
Results: In this study, 439 (37.5%) were ventilator-related events (VAEs), and 46% of all hospitalized patients had an under- lying disease. The most common microorganisms in COVID-19 patients were carbapenem resistant Klebsiella pneumoniae (KPCs) (31.6%), Escherichia coli (E. coli) (15.8%), and Acinetobacter baumannii (A. baumannii) (15.7%), respectively. Prevalence of vancomycin-resistant enterococci (VRE) and KPCs were 88% and 82%, respectively.
Conclusion: A study on AMR surveillance is the need of the hour as it will help centers to generate local antibiograms that will further help formulate national data. It will guide doctors to choose the appropriate empiric treatment, and these studies will be the basis for establishing antimicrobial surveillance and monitoring and regulating of the use of antimicrobials.
Simultaneous detection and differentiation of Mycobacterium tuberculosis and nontuberculous mycobacteria coexisting in patients with pulmonary tuberculosis by single-tube multiplex PCR
Authors: Heidari Leila , Dehbidi Gholamreza Rafiei , Farhadi Ali , Kashkooli Golnar Sami , Zarghampoor Farzaneh , Namdari Sepide , Seyyedi Noorossadat , Fard Saeid Amirzadh , Behzad-Behbahani Abbas
Published: June 2023

Background and Objectives: In clinical diagnostics, molecular methods are used to detect Mycobacterium tuberculosis bacilli (MTB) and to distinguish them from non-tuberculous mycobacteria (NTM). They are also used to make the right treatment decision for the patient as soon as possible. The aim of this study was to establish a rapid and novel multiplex PCR (mPCR) assay for the detection and differentiation of MTB and NTM in a single tube.
Materials and Methods: 100 sputum samples positive for acid-fast bacilli (AFB) were included in this study. Mycobacterial culture, biochemical tests, and antibiotic susceptibility testing were performed on samples. After alkaline decontamination, total DNA was extracted from the samples. A primer pair targeting the rpoB gene, encoding the beta-subunit of RNA poly- merase, was used to detect MTB and NTM, amplifying a 235-bp fragment of MTB and a 136-bp sequence of NTM. A pair of primers targeting a 190-bp fragment of the IS6110 region of MTB was also used to confirm the results. The sensitivity and specificity of the mPCR assay were evaluated using DNA extracted from standard strains. The amplified products were then analyzed by conventional agarose gel electrophoresis.
Results: Of 100 AFB smear-positive sputum samples, 92 MTB DNA, 7 NTM DNA, and one mixed-infection sample were identified in a single tube using mPCR assay. There was no correlation between the AFB degree of smear positivity and PCR results. Of seven NTM isolates, 6 (86%) were resistant to rifampin, isoniazid, and ethambutol, the three first-line anti-tuber- culosis drugs.
Conclusion: A single-tube mPCR assay based on the rpoB gene provides a rapid and reliable means of detecting and differentiating MTB and NTM in sputum specimens.
Inhibition of bacterial adhesion and anti-biofilm effects of Bacillus cereus and Serratia nematodiphila biosurfactants against Staphylococcus aureus and Pseudomonas aeruginosa
Authors: Keyhanian Alireza , Mohammadimehr Mojgan , Nojoomi Farshad , Naghoosi Hamed , Khomartash Mehdi Shakouri , Chamanara Mohsen
Published: June 2023

Background and Objectives: Biosurfactants are amphiphilic surface-active agents that mainly produced by various micro- organisms. In this study, the anti-biofilm and inhibition of bacterial adhesion activities of two bacterial biosurfactants were investigated.
Materials and Methods: After extraction and evaluation of Bacillus cereus and Serratia nematodiphila biosurfctants, inhi- bition of bacterial adhesion and anti-biofilm effects of them on Staphylococcus aureus and Pseudomonas aeruginosa were determined.
Results: On average, the synergistic effect of two bacterial biosurfactants, caused about 60% decrease in adhesion and about 80% decrease in biofilm formation of S. aureus and P. aeruginosa.
Conclusion: The results of this study showed that combination of B. cereus and S. nematodiphila biosurfactants would in- crease the potential of attachment inhibition and biofilm eradication with very low toxicity.
Histopathological characteristics and HPV status in cervical biopsy specimens diagnosed as flat condyloma
Authors: Nategh Fatemeh , Mohit Mitra , Saatian Minoo , Farahmand Zohreh , Soleimanjahi Hoorieh
Published: June 2023

Background and Objectives: HPV infections cause a wide spectrum of pathological changes in lower anogenital epithe- lium. The aim of this study was to investigate the HPV DNA status and histological findings in cervical biopsy specimens diagnosed as flat condyloma.
Materials and Methods: This study included 20 cervical biopsy specimens diagnosed as flat condyloma. The histopatholog- ical criteria and presence of HPV DNA were evaluated. HPV genotyping was determined in HPV-positive specimens using BioEdit software and the results were analyzed in SPSS software.
Results: HPV DNA was not found in 30% of specimens and relative frequency of HPV genotypes was: 15% HPV6, 15% HPV11, 5% HPV16, 5% HPV18, 5% HPV53, 5% HPV68, 5% HPV84, 10% HPV45. Relative frequency of histopathologi- cal criteria was as below: 100% of specimens had koilocytosis, 100% acanthosis, 15% nuclear immaturity, 100% atypia, 15% mitotic activity, 50% dyskeratosis, 35% parakeratosis and 10% hyperkeratosis.
Conclusion: There were significant differences between HPV positivity and two pathologic criteria; multinucleation and hyperkeratosis (P Value: 0.02). Nuclear immaturity was significantly more prevalent in high risk HPV-positive specimens (P Value: 0.03).
Sensor based real time air pollutants monitoring for an urban industrial area
Authors: Lambey Vinit , Prasad A. D.
Published: June 2023

Introduction: This study used economical sensors and an Unmanned Aerial Vehicle (UAV) to examine real-time air pollution assessment for an urban industrial area.

Materials and methods: Using a DJI Phantom 3 Pro, the concentrations in the research area were measured. In the study, Carbon monoxide (CO) and Nitrogen dioxide (NO2) were measured using metal oxide sensors, and Particulate Matter (PM10) was determined using a dust smoke particle sensor. Pollutants were measured at heights of 0.8 m and 10 m for a period of one month.

Results: With an increase in elevation, a gradual drop in pollutant concentration has been seen. High traffic volumes and fuel combustion are to blame for this increase. The concentration of CO, NO2 and PM10 at 0.8 m has been found to be 22.53%, 42.90% and 45.86% respectively higher when compared at 10 m. The main finding of this study is the use of an UAV integrated with sensors for vertical monitoring of the pollutant concentration.

Conclusion: The CO concentration was found to be less than the standard value but near to it, when the data were compared to the Central Pollution Control Board (CPCB) standards. While it was discovered that the measured PM10 concentration was higher than the CPCB standard value, the observed NO2 concentration was determined to be lower than the standard value. Also, given that they produce satisfactory results, low-cost gas sensors can be employed to conduct concentration measurement studies.
Using a Gaussian model to estimate the level of particle matter concentration on paved and unpaved roads in urban environment: A case study
Authors: Yannick Cédric Ngangmo , Cyrille Mezoue Adiang , Charitos Mah Serges , David Monkam
Published: June 2023

Introduction: In both developed and developing countries, re-suspension of dust particles along the road owing to tire and brake wear is the most common source of Particulate Matters (PM) pollution in metropolitan areas. This study in Douala analyses the effects of paved and unpaved roads on particle matters concentration thresholds in urban environments.
Materials and methods: The United States Environmental Protection Agency (US EPA)'s model AP-42 equations were used to calculate the amount of particle matter emissions on the roads. Between 6 am and 8 pm, a traffic analysis using information from the city of Douala was conducted. The busiest times for traffic were from 8 to 9 a.m. and 6 to 7 p.m. We applied a two-dimensional Gaussian model to determine the particle concentration. Two different scenarios were taken into account: Compared to Scenario 2 (S2), Scenario 1 (S1) represents an unpaved road. The PM10 and PM2.5 types of particles were the main topics of interest.
Results: We obtained for S , around 917.70 µg/m3 and 559.00 µg/m3 respectively for PM and PM . We got roughly 170.00 µg/m3 and 103.90 10 2.5 µg/m3 for S , respectively for the two particles. The amount of silt deposited on the road, the kind of road (paved or unpaved), the number, and the types of vehicles moving all influence the emission of road dust re-suspension. Regardless of particle size, these pollution levels are beyond World Health Organization (WHO) recommended norms.
Conclusion: This study offers important information on Douala's pollution levels, which can be a significant cause of disease in the area and should be considered.
Development of indoor work environmental air quality index for a dyeing and printing industry
Authors: Jariwala Dharmendra , Christian Robin
Published: June 2023

Introduction: Due to various components, materials, and processes, industrial indoor air quality differs from building indoor air. Air quality and the working environment impact health, performance, and comfort. This study developed an Indoor Work Environmental Air Quality Index (IWEAQI) to assess and characterize industrial work environments.
Materials and methods: Surat “Textile city” is situated in the western part of India in Gujarat state. The small-scale dyeing and printing industry has been selected as a study area. The industry locations like Jet dyeing machine area, stenter machine area, printing machine area, looping machine area and washing basin area has been selected. Various chemicals, adhesives, solvents, dyes, and varied temperature and humidity conditions are used to transform the raw cloth into the finished product. CO, CO2, SO2, NO2, O3, Total Volatile Organic compounds (TVOC), Formaldehyde, Particulate Matters (PM10, PM2.5), WBGT index, humidity, noise, and light were considered to construct IWEAQI. Continuous observations were recorded at minute intervals with a real-time monitoring system. To account for all contributing aspects, United States Environmental Protection Agency (USEPA) air quality index technique was updated for index formulation. IWEAQI was validated using the Pollution Index approach.
Results: The proposed approach calculated IWEAQI from results. Both approaches gave an index value of 46-80. The developed approach and pollution index method were compared using regression analysis. All study locations had regression values between 0.93 and 0.99.
Conclusion: The technique classifies IWEAQI as excellent (0-20), good (21-40), moderate (41-60), poor (61-80), and very poor (81-100). From the developed index value, which parameters are influencing the most can be judged.
How to approach a colleague’s error: a journey from moral knowledge to moral action
Authors: Khaleghparast Shiva , Maleki Majid , Dehaki Maziar Gholampour , Homami Setareh , Sadooghiasl Afsaneh , Mazloomzadeh Saeideh , Gooshki Ehsan Shamsi
Published: June 2023

The Article Abstract is not available.
LEGISLATIVE PROCESSES AND PRACTICES IN PAKISTAN: A PERFORMANCE ASSESSMENT OF PEOPLE’S PARTY PARLIAMENTARIAN (PPPP) DURING 2008-2013
Authors: Zaman Ali , Waris Muhammad , Iqbal Sarvat , Zaman Hafiz Muhammad , Aslam Sundus
Published: June 2023

Purpose: The present study intends to analyze the Pakistan People’s Party government period from 2008 to 2013 after the demise of its leader Benazir Bhutto. The study is about the PPPP government on the issue of legislation in the parliament so a qualitative method is used for this purpose.

Method: The topic is related to legislation, so the primary and secondary sources used with the complete lists of legislation from 2008-2013 from the parliament websites and documents.

Main Findings: It was found that the legislative process was fast during the PPPP regime. Still, some areas of governance remained neglected like health, education, energy, etc. Overall the democratic values and coalition strategies supported the government in the completion of its tenure.

Application of the Study: It is recommended that ruling elites must focus on good governance and citizens' well-being rather than their opposition.

Novelty/originality of the study: This study has a distinction from other studies in the sense that the way of the legislative process of PPP has never been assessed before in the context of their performance. This study will make able to understand the importance of PPP’s government in place of democratic norms.
19. Yüzyıl Ortalarında İstanbul’da Hanlar: Mekânsal Bir Analiz
Authors: Yaşar Ahmet
Published: June 2023

Bu makale, 19. yüzyılın ortalarında Osmanlı İstanbul’unda mevcut han ve bekâr odaları üzerinedir. Çalışma, Evkaf Defterleri arasında yer alan, başkentte kâin toplam 593 han ve bekâr odasına dair kapsamlı bilgiler ihtiva eden iki deftere dayan- maktadır. Bu defterler İstanbul’u 26 kola ayırarak 418’i ‘han’ ismiyle, 175’i ise ‘bekâr odası ya da oda’ ismiyle anılan 593 yapıyı kaydetmişlerdir. Bu iki defterdeki kayıtlar, özellikle hanların İstanbul şehir mekânsal düzlemindeki yerleri ve şehirde yoğunlaş- tıkları bölgeleri, oda sayıları, vakıf sahipleri ve han ve bekâr odası ayrımı hususlarında çok önemli veriler sunmaktadır. Bir istatistik devletine dönüşen siyasi iktidar tarafın- dan oluşturulmuş olan bu tahrirler 19. yüzyılın ikinci yarısında Osmanlı İstanbul’unun değişimi ve dönüşümü eşiğinde şehiriçi hanlarının en erken tarihli ve kapsamlı bir dökümünü ortaya koyma imkânı sunmaktadır. Makale çerçevesinde defterlerin tanıtımı yapıldıktan sonra, Coğrafi Bilgi Sistemleri (CBS) kullanılarak hanların yoğunlaştığı bölgeler, belli başlı hanlar, han oda sayısı, han ve bekâr odası farklılıkları gibi mevzular ortaya konulmaya ve hanların bir listesi çıkarılmaya çalışılacaktır.
Ebubekir Ceylan, Modern Irak’ın Osmanlı Kökenleri,
Authors: Güzeloğlu Efe
Published: June 2023

Ebubekir Ceylan’ın bu çalışması, 1831’den 19. yüzyılın son çeyreğine uzanan zaman aralığında Osmanlı Irak’ının ya da Bağdat Vilayeti’nin modernleşme ve idari anlamda merkezileşme sürecinin bir anlatısıdır. Vakıfbank Kültür Yayınları tarafından yayımlanan kitap, Ceylan’ın Boğaziçi Üniversitesi’nde tamamladığı doktora tezine dayanmaktadır ve kitabın İngilizce orijinali daha önce I. B. Tauris tarafında basılmıştır.
Noel Malcolm, Useful Enemies: Islam and the Ottoman Empire in Western Political Thought, 1450-1750,
Authors: Thaçi Atdhe
Published: June 2023

Ottoman historians in the last decade have focused a lot on Ottoman political thought. This means how the thoughts and writings of different Ottoman scholars, which mainly included the religious strata and other intellectuals, influenced political thought and political decisions in the Empire. Now with the book written by Oxford Professor Noel Malcolm, we have another side of that story.
Ahmet Şefik Şenlik, Tiryâkî Hasan Paşa Gazavâtnâmesi ve Bazı Filolojik Notlar,
Authors: Uysal Abdülhadi
Published: June 2023

Türk dili ve grameri, Osmanlı devrine ve öncesine ait Türkçe tarihi metinler ve klasik Türk musikisi başta olmak üzere farklı konularda ve disiplinlerde yaptığı çalışmaları ile tanınan ve bunları birbirinden tamamen ayrı araştırma alanları olarak görmeyip Türkoloji şemsiyesi altında bir arada incelenmesi gereken bir bütün olarak mütalaa eden Prof. Dr. Ahmet Şefik Şenlik’in Tiryâkî Hasan Paşa Gazavâtnâmesi üzerine hazırladığı filolojik mahiyetteki eserinin, neşrinin üzerin- den uzun denebilecek bir müddet geçmiş olmasına rağmen ehemmiyeti nispetinde ilgiye mazhar olmamış ve dikkatlerden kaçmış olduğu söylenebilir.
Considerations about interference RNA for the control offungal diseases in Mexican and Latin American agriculture
Authors: Couoh-Dzul Osvaldo Jhosimar , Carreón-Anguiano Karla Gisel , Moreno-Valenzuela Oscar A. , Canto-Canché Blondy
Published: June 2023

The control of phytopathogens is keyfor food security. In the last decade, the use ofinterference RNA (iRNA) has been proposed as atechnological tool for controlling diseases and pestsin agriculture. Although different approaches havebeen described, such as the use of “Host-InduceGene Silencing” (HIGS) and “Virus-Induce GeneSilencing” (VIGS), more recently a non-transgenicand environmentally friendly approach hasemerged, called “Spray -Induce Gene Silencing (SIGS), which uses double-stranded “naked” RNA(dsRNA). This review discusses recent reportson the use of dsRNA, especially SIGS, to controlphytopathogenic fungi; emphasizing factors suchas efficacy, safety in terms of human health andits stability in the environment. It also focuses onimportant phytosanitary problems in Mexico andLatin America that can be addressed with SIGS.This review concludes that SIGS technology hasreal potential to be used to control phytopathogenicfungi on plants in the field and on postharvestfruits. At the end, the critical tasks and the linesof research that must be carried out to promote theSIGS to make it a reality are considered.
University business incubators and opportunities for collaboration with companies within the start-up 2
Authors: Kazhenov Saken
Published: June 2023

Business incubators based on the university mainly target social impact by creating opportunities for job creation, and profit is not the primary objective. However, companies are doing business, and there should be strong reasons to attract them in collaboration with the university. This paper aims to find the possibilities for collaboration between university business incubators and companies. To achieve this purpose, we used the data from scientific articles. The review is based on the content analysis of the relevant papers in the three-level approach (individual, organisational and institutional). Similar to other entrepreneurship-supporting organisations, university business incubators connect start-ups with mature companies or industry leaders to allow faster growth for new ventures. This research illustrates that the most significant types of collaboration for all three levels (individual, organisational and institutional) are mentorship and networking. The suggestions of this paper give an overview of the incubation process to entrepreneurship researchers.
Keywords: Business incubator, entrepreneurship, networking, start-ups, university, university-industry collaboration;
Online Fatwas in Pakistan using Social Networking Platforms
Authors: Adel Samiullah , Numan Muhammad
Published: June 2023

In the era of digital communications, religious dialogues have experienced significant transformations, notably with the rise of online fatwas via social media platforms. The spread of these digital religious verdicts has broadened the dissemination of information and public engagement while challenging traditional boundaries of freedom of speech. This research, grounded in the context of Pakistan, explores the implications and effectiveness of online fatwas. Through a qualitative approach, this study examines various social media platforms widely used in Pakistan to deliver online fatwas. The findings of this study suggest that these platforms have democratized religious discourse, shifting it from physical, sacred spaces such as mosques to the digital sphere. Furthermore, these platforms significantly influence individual beliefs, societal norms, and behaviors, thereby contributing to shifts in socio-political structures. Given the powerful influence of these platforms, the need for vigilant scrutiny and regulation is underscored. This study, therefore, offers critical insights into the digital transformation of religious practices and its vast implications for societal structures and individual behaviors. The conclusions drawn from this research could guide the management and dissemination of online fatwas, ensuring a balanced and beneficial societal impact.
Communities at war: Labelling perspective on hostility between communities and illicit immigrants in South Africa
Authors: Malatji Thabiso , Rakubu Kholofelo
Published: June 2023

Despite all the migration policies implemented in South Africa and the world at large, the illicit immigrants continue to suffer in the hands of the host communities. This paper seek to address the challenges and experiences of illegal immigrants in South Africa and the hostility by the host communities. In this qualitative study, linguistic data was collected through the focus group discussions with illicit immigrants from different countries in the African continent as well as the blinded focus group with communities in Limpopo province. The aim of the study was to explore the hostile environment that the illicit immigrants find themselves in while in South Africa and the problem of integration with the host communities. Findings from this study revealed that the illicit immigrants continue to become a problem in the receiving communities, and this is because they are snatching job opportunities for the locals since they do not mind exercising cheap labour, that’s is why there is tension between them and the locals. Most employers prioritise employing illicit immigrants instead of the locals. Furthermore, the participants indicated that the immigrants continue to temper with job security in the host communities. The researcher conducted two focus group discussions, one consisted of illicit immigrants from different African countries like Zimbabwe, the Democratic Republic of Congo, Malawi and Burundi, and the other focus group with the locals as blind group discussion. This is conceptualized as fear or black-on-black hatred which is also famously known as Afrophobia