bluuebunny/crossref_metadata_2025 huggingface dataset:
Improving Indian meteorological department method for 24- hourly rainfall downscaling to shorter durations for IDF modelling
Authors: Nwaogazie Ify L , Sam Masi G , Ikebude Chiedozie
Published: May 2021

The development of Intensity-Duration-Frequency (IDF) models for storm drain design and related flood mitigation structures requires rainfall amount and corresponding duration records. To achieve this purpose, three short duration downscaling methods from 24-hourly rainfall amount data were selected for improvement, namely: IMD, AIMD and MCIMD, with the CAMS method used as the experiment control. Three types of general PDF-IDF models (GEVT-1, LPT-3 and ND) were developed based on the downscaling methods yielding goodness of fit (R2) with very high correlation of 0.995–0.999 and model accuracy with mean square error (MSE) of 4.123–7.85. The PDF-IDF models predicted intensities plotted against durations for different return periods of 2, 5, 10, 25, 50 and 100 years, showed visual differences in the predictive performance of the intensities derived from the downscaling methods. Kruskal-Wallis non-parametric test of significance at 5% level carried out showed that no-significant difference exist for 15-60 minutes duration, while the difference was significant for durations between 90–300 minutes. The LPT-3 based on MCIMD yielded higher improved performance in prediction of intensities relative to the IMD. The level of improvement ranges from 35.17 to 52.26% and 25.0 to 39.89%; while that of AIMD ranges from 10.97 to 20.87% and 3.33 to 12.53% for 10 and 100 year return periods, respectively. The use of the IMD downscaling method with the LPT-3 PDF-IDF model for design purposes will be justified if modified with some percentage improvement or adjustment factor.
Influential ethical aspects of Covid19 in multidimensions
Authors: Rajan MA Jothi , Sheeba Rani M Arul
Published: May 2021

The COVID19 pandemic poses an exceptional challenge for humanity. Because public behavior is key to curbing the pandemic at an early stage, it is important for social psychological researchers to use their knowledge to promote behaviors that help manage the crisis. Here, we identify human values as particularly important in driving both behavioral compliance to government guidelines and promoting prosocial behaviors to alleviate the strains arising from a prolonged pandemic. Existing evidence demonstrates the importance of human values, and the extent to which fellow citizens, for tackling the COVID19 crisis, share them. Individuals who attach higher importance to self‐transcendence (e.g., responsibility) and conservation (e.g., security) values are likely to be more compliant with COVID19 behavioral guidelines and to help others who are struggling with the crisis. Further, believing that fellow citizens share one's values has found to elicit a sense of connectedness that may be crucial in promoting collective efforts to contain the pandemic. The abstract nature of values, and cross-cultural agreement on their importance, suggests that they are ideally suited to developing and tailoring effective, global interventions to combat this pandemic
ELISA validation approach for the detection of anti-saccharomyces cerevisiae antibodies in patients treated with biopharmaceutical heberprot-P®
Authors: Bernal Maylin Pérez- , Hernández Carlos , Delgado Magali , Izquierdo Mabel , Rosales Ileana , Pérez Enrique
Published: May 2021

This work describes the validation of an enzyme-linked immunosorbent assay (ELISA) for detection of anti-Saccharomyces cerevisiae antibodies (ASCA) in diabetic patients with foot ulcers, after the treatment with Heberprot-P®. Validation followed regulatory guidelines of US FDA and European Medicine Agency. Minimum required dilution of samples and quality controls were defined using pools of sera from diabetic patients and from healthy donors. Parameters such as cut point, specificity, precision, selectivity, robustness and sample stability were analyzed. The repeatability and intermediate precision percent ranged between 7.93-10.61% and 7.93-11.43 %, respectively, indicating low intra- and inter-assay variation. The specificity was proved by background noise suppression, reaching 100% of inhibition as strong criterion for the specificity of the immunoassay. The validated ELISA is a reliable tool for ASCA detection in human serum after the administration of Heberprot-P®, in order to find immunological reactions associated with latent contamination by host cell proteins from Saccharomyces cerevisiae.
Immunomodulatory activity in tumor-bearing mice treated with Withania somnifera extract
Authors: Melo Adriana de , de Melo André Luiz , Marcucci Maria Cristina , Carvalho Claudemir de , Gonçalves Carolina Passarelli
Published: May 2021

We investigated some actions of Withania somnifera on the growth and differentiation of hematopoietic precursors [granulocyte/macrophage colony cell formation (CFU-GM)] of normal animals and EAT bearers, which were treated with different doses (20, 50, or 100 mg/kg/day). We also evaluated the presence of colony stimulatory factors in the animal's serum, as well as its survival. Furthermore, we analyzed lymphocyte proliferation, IFN-ɤ, and TNF-α concentrations in treated bearing mice. Our results demonstrated Withania somnifera effectiveness on hematopoietic precursors growth and differentiation in marrow and spleen TAE-bearing mice. As it was already expected, EAT produced myelosuppression and increased CFU-GM spleen number concomitantly. The treatment of EAT-bearing animals with W.S. (20, 50, and 100 mg/Kg) produced a dose-dependent increase in myelopoiesis, an increase in a lifetime, and a reduction in spleen colony number. All this happened parallel to survival. As to lymphocyte proliferation, they were also dose-dependent in treated bearing animals. Concerning IFN-γ levels, we observed a significant reduction in non-treated bearing mice. Levels of TNF-α of treated bearing mice significantly increased when compared to the non-treated bearing group. These results are encouraging since they favor the use of W.S. extract in therapeutic combinations with other chemotherapeutic agents to reduce myelotoxicity and supplement the tumoricidal efficacy of this plant.
Necrotizing panniculitis secondary to primary cutaneous localized mucormycosis
Authors: Velasco M Llamas
Published: May 2021

Primary cutaneous mucormycosis is a rare entity that affects more frequently extremities of immunosuppressed patients and may be gradual in onset or fulminant. An 83-year-old female with diabetes mellitus presented a nodular lesion in the forearm, which had progressed during one month. Clinically, as the lesion was indolent and followed a linear trajectory, a superficial phlebitis was suspected but later ruled out. Skin blood cultures were negative. Skin biopsy showed a necrotic panniculitis with isolated ghost adipocytes and presence of irregularly branched hyphae involving dermis and some vessels that could be stained with PAS and Grocott, thus leading to the diagnosis of primary cutaneous localized mucormycosis. This case is noteworthy as indolent course in primary cutaneous mucormycosis with vascular involvement is rather rare. Even with a negative culture, R. Variabilis is a candidateetiologic agent as it usually presents a chronic evolution. Histopathologically, most panniculitis related to fungal infection are reportedas pancreatic panniculitis mimickers. In our case, only scarce ghost adipocytes were found and the main histopathological findings were a lobular panniculitis with vasculitis and an extensive basophilic necrosis. Thus, these histopathologic findings should raise suspicion of infection related-panniculitis, and PAS and Grocott stainings should be performed to rule out fungi.
Respiratory muscles power reversibility test as a new test in asthma diagnosis
Authors: Elbedri Abdalla Omer Abdalla , Musa Omer A
Published: May 2021

Making diagnosis of asthma requires a critical evaluation of the patient’s symptoms, medical history, physical examination and diagnostic tests. It is known that a reduction of respiratory muscle pressures (MIP and MEP) for assessment of respiratory muscles power has been associated with several neuromuscular diseases, but it is also possible to point out lower values in patients with chronic obstructive pulmonary diseases as in asthma. As asthma diagnosis by reversibility test is not very sensitive in intermittent and mild asthma and pulmonary function is related to respiratory muscle pressures (RMP), could we use the reversibility of RMP in the patients for asthma diagnosis is the main issue investigated in this research. The aim of the study to determine the validity of asthma diagnosis by reversibility testing of respiratory muscles power. A cross-sectional hospital based study carried out in Lung function tests clinic in Police and Alban Gadeed hospitals in Khartoum during the years 2010-2011 to determine the reversibility of the lung function (FEV1 and PEFR) and respiratory muscles power (MEP and MIP). Thirty five known asthmatic subjects attending the referred chest clinic for follow up, and 20 healthy non asthmatic controls were included in the study. FEV1, PEFR, MEP and MIP were measured for all subjects before and after bronchodilator. Reversibility test was considered positive assuming the cut-off point for FEV1, MEP and MIP is ≥12% and for PEFR≥20%.The results showed percent of change in asthmatic group before and after bronchodilator test for FEV1 , PEFR, MEP, MIP were: 10.45, 11.84, 12.15 and 16.73 respectively. The difference was statistically significant. Sensitivity and specificity of reversibility testing for FEV1 (40%, 75%), for PEFR (31%, 65%), for MEP (49%, 70%) and for MIP (71%, 65%). In conclusion, the respiratory muscles power reversibility test could be a potentially sensitive diagnostic test for asthma
PM2.5, PM2.5-related air pollutants, health hazards and impacts on respiratory and cardiovascular disorders and diseases: systematic review and meta-analysis
Authors: Cheepsattayakorn Attapon , Cheepsattayakorn Ruangrong
Published: May 2021

The objective of the study is to perform a critical review, exploration, and strong summary of the relationships between personal and ambient concentrations of mainly particulate matter with diameter of 2.5µm or less with the measures of cardiopulmonary health. A comprehensive search was carried out in mainstream bibliographic databases or Medical Subject Headings, including Scien Direct, PubMed, Scopus, and ISI Web of Science. The search was applied to the articles that were published between 2017 and early 2019. Needed article information was extracted from each article by: direct information including journal (research article, review article, meeting abstract, conference abstract, correspondence, author index, editorial board meeting abstract, discussion), book chapter, title, authors, abstract, full text documents of candidate studies, publishing year. Study period, Research (study) method used, types of air pollutants variables studied; Types of organ system disorder or disease studied The conclusions made about the health hazards, impacts on humans or animal models, novel therapeutics, and economic loss. With strict literature search and screening processes, it yielded 140 articles (2017=45; 2018=61; and early 2019=34 articles) from 3,968 articles of initial literature database (1952-early 2019). The main compositions of air pollutants are PM, particularly PM2.5 and PM10, O3, CO, SO2, and NOx. Exposure to O3 is frequently associated with respiratory tract inflammation, whereas exposure to PM, CO, No2, and SO2 is related to pulmonary edema, respiratory and cardiovascular hospitalizations, and cardiopulmonary mortality. Any compromise to endothelial cells, the key components of lung barrier integrity contributes to vascular leakage and inflammation. Endothelial cells could be the target of PM exposure. The various effects on various disease entities contribute to hypothesize that Melatonin might protect the lung integrity against PM2.5-induced acute lung injury. Bufei Huoxue (BFHX) could reduce secretory immunoglobulin A (sIgA) and collagen fibers deposition in lung, thus, improved pulmonary function. In conclusion, identification of various crucial signaling pathway involving PM-induced cardiopulmonary disorders and diseases may assist in the development of effective therapeutics, including clean energy use, clean industrialization, proper agriculture, high land use diversity, and proper urbanization for reduction of the air pollution.
Comparative analysis of China (Han) & Bangladesh cultural authentication and transformation context on “Motif Design”
Authors: Moniruzzaman Md , Nizam Md Eanamul Haque , Hasan Md Tanjubul , Karim Md Ahosanul , Shammi Maria Afrin , Raisa Lamia Nasif
Published: May 2021

Now a day, fashion design and clothing manufacturing is going to update day by day. Modern fashion designers are interested to work with the new color, trend, design, pattern, cutline. “Motif Design" and its application may have been a positive way to deal with the ideal tasteful look, while social confirmation and diversification have been considered as key factors. In this study, the author tries to investigate the cultural elements motif between Bangladesh and china (Han). The author investigates different Blogs, magazines, journals, and websites used for the analysis. In order to make this research authentic and credible different local and international published books and articles have been studied. Different websites helped by representing historical progress and reference of the information which adorned in this research. Few Bangladeshi and Chinese apparel fashion brands those who worked with traditional costume were also a way to understand today's influence of Cultural elements. After the analysis, the author finds some features of motif like style, positioning, color and pattern. The research team analyzes those points from the view of two sides. Then the authors finally find out the key similarities from the analysis between the two countries. From the finding, the author designs (flat sketch) a series of dresses for the Contemporary market for future sustainability.
Using textile waste as a sustainable alternative to underground irrigation in Brazil’s semi arid region
Authors: Nascimento Nicéa , Salvado Luísa Rita Brites Sanches
Published: May 2021

The problem of water scarcity has been the subject of major discussions in society and among governments. Water is a fundamental resource for the survival of living beings and is becoming increasingly scarce, with projections showing that one in four people on Earth may be suffering from extreme water scarcity by the year 2025. Irrigation is the artificial application of water to the soil in order to maintain adequate moisture for the growth of a given crop. Among the various types of irrigation, underground irrigation is promising for use in regions with water scarcity, since water can be transported directly to the plant roots, with little loss due to surface evaporation, as happens in other types of irrigation, such as sprinkling. Thus, due to this growing water scarcity and excessive use of water by agriculture, and considering the importance of irrigation for the promotion of food and nutritional security of populations, this work presents as an alternative the use of textile waste for an application in agriculture, proposing a sustainable solution for the destination of waste from the fashion industry that are usually dumped in the trash, generating environmental problems. The development of the simple technology of subterranean irrigation based on textile residues, presented here, led to the rational use of water in constructed experimental seedbeds, without apparent damage to the development of crops, which may strengthen family farming and have a significant impact on the economic growth of the region, if the technology is applied in scale. In general, all the experimental field results demonstrated that the devices developed with pieces of synthetic textile waste were able to transport water to distant areas of the soil, keeping it moist at root level and contributing to better growth of the tested plants. In other words, all the devices constructed to enable subterranean textile irrigation by capillarity worked adequately, in a qualitative analysis. The idealized and tested devices have in common the fact that they are grassroot technologies, low cost, easy to build, implement and maintain; simplicity; possibility of mastery of the technology by the beneficiaries themselves; and generators of shared knowledge between the proponents and the beneficiaries. In short, potential generators of social impact for this population that needs inclusive solutions so much.
Application of natural dyes from selected indigenous plants on cotton and silk fabrics
Authors: Loum Janani , Byamukama Robert , Wanyama PAG
Published: May 2021

Standard procedures for mordant dyeing were used to dye plain weave cotton and silk fabrics with dye from four selected indigenous plants viz: A. coriaria, V. paradoxa, M. lucida and H. madagascarensis. Alum and ferrous sulphate mordants were with the following mordanting methods; pre, simultaneous and post mordanting. Color fastness was used as a basis to evaluate the performance of each method. Color strength imparted on fabric was used as a basis to optimize the following selected dyeing variables viz: temperature, dyeing time, material to liquor ratio (M:L), and mordant concentration (o.w.f). Mordant dyeing under optimized conditions improved color strengths and fastness on both cotton and silk fabrics. According to the optimized variables, silk fabrics required a little more heating (80˚C to 95˚C) for a longer time (≈ 1hr 30mins) than cotton to achieve optimal strengths of color. The fastness obtained for various fastness characteristics on both fabrics dyed under optimized conditions varied from fairly good (3) to excellent (5) with cotton giving better fastness. However, silk recorded better color strength in term of k/s values in the range of (110 to 260) and more lustrous appearance was observed on it. Dye from M. lucida plant species recorded overall superior color characteristics on both fabrics and with both mordants.
Dorsolumbosacral agenesis: Case report and literature review
Authors: Camacho Montaño Andrés Mauricio , Reinaldo Reinaldo Child Alba , Grajales María Camila Cetina
Published: May 2021

Objetives: To report a case of dorsolumbosacral agenesis and to make a systematic review of the literature focused on prenatal diagnosis. Materials and methods: We report a case of a 32year old pregnant woman, with a 30 week pregnanacy, without prenatal care, the fetus is diagnosed with dorsolumbosacral agenesis. The mother request voluntary termination of pregnancy. A systematic review of the literature focused on prenatal diagnosis of thos condiction is performed. Results: We found 50 papers, 6 met the inclusión critiria. Three of them with prenatal diagnosis. In the first case the diagnosis was made at 13 weeks of gestation and termination of preganancy was requested. In the second case corresponded an biamniotic bicorial twin preganancy. One normal feto and one presented dorsolumbosacral agenesis. The diagnosis was made in the second trimester. The pregnancy continued until 34 week of gestation and the affected neonate had perinatal death. The third case, the diagnosis was made at 18 weeks and a male newborn of 2990gr was born at 37 weeks of gestation. Conclusion: Dorsolumbosacral agenesis is a very severe form of caudal regresión syndrome, with only a few cases reportted in the literature. To the best of our knowladge this is the fourth case reported with prenatal diagnosis.
Analysis of the Comparative Western Democracy, Pancasila Democracy, and the Concept of Shura; Study of the Book Manuscript "Democracy in Islamic Perspective by Ahmad Sukardja and Ahmad Sudirman Abbas"
Authors: Nurhasan Nurhasan , Rohmah Siti Ngainnur
Published: May 2021

Democracy that comes from the West is often juxtaposed with the concept of shura in Islam. The concept of shura is often seen as having an intersection with democracy. There are those who agree and there are those who are not in line with democracy. Those who agree with democracy argue that the value of democracy is universal and can coexist with Islam. The opinion that rejects an Islamic state (caliphate) and justifies democracy states that the legacy of the Islamic political system is based on the experience of the Caliphate with no standard standards. The author is interested and compelled to examine how Western Democracy, Pancasila Democracy, and the concept of Shura in an Islamic perspective? How do we compare the principles of western democracy, Pancasila Democracy and the concept of Shura in the book "Democracy in an Islamic perspective by Ahmad Sukardja and Ahmad Sudirman Abbas?" This study uses a qualitative research method, with a manuscript study approach. The results of this study state that Western Democracy and Pancasila Democracy in essence do not contradict the Shura principles, as long as the principles in them are in accordance with the essence of Islamic teachings. Western democracy is bound by equality of blood, race, language, and customs, whereas in Islam it does not see this bond as a barrier. Al-Qur'an and Al-Sunnah are more general in nature and cover all aspects of human life throughout the world. Meanwhile, Pancasila Democracy is only suitable for a country.Keyword: Western Democracy, Pancasila Democracy, Shura Concept, Islamic Perspective
O novo espírito da depressão
Authors: Peters Gabriel
Published: May 2021

O artigo arrisca uma interpretação sociológica da suposta “pandemia de depressão” que assola a contemporaneidade. Os mal-estares psíquicos comumente descritos como experiências depressivas são compreendidos à luz das formas de subjetividade produzidas ou, pelo menos, encorajadas pela modernidade tardia. Com base no retrato sócio-histórico do “novo espírito do capitalismo” formulado por Boltanski e Chiapello, o texto defende que os atributos de iniciativa, empreendedorismo e adaptabilidade tornaram-se imperativos da individualidade contemporânea não somente no mundo do trabalho, mas também em diversos outros domínios existenciais, tais como o cuidado com o corpo e as relações erótico-afetivas. Sem desconsiderar a inflação de diagnósticos psiquiátricos como parte das causas por trás da alegada pandemia de depressão na atualidade, o trabalho sustenta que as formas muito reais de sofrimento psíquico classificadas nesses termos são a moeda reversa, por assim dizer, de demandas sistêmicas pela autorrealização individual: o colapso depressivo da iniciativa e a ausência de “projetos” substituem o “empreendedorismo de si”; a interrupção do movimento sobrepuja a adaptabilidade flexível do self a uma sociedade de mudanças aceleradas; e a experiência do isolamento existencial substitui a esperada comunicabilidade do sujeito-trabalhador contemporâneo como infatigável networker. O trabalho conclui com uma reflexão sobre os limites que a civilização contemporânea coloca à “ecologia psíquica” e à “economia energética” dos indivíduos nela imersos.
Oncotherapeutics: A General Overview
Authors: Ghosh Dr. Sayantan , N Ms. Manaswi
Published: May 2021

Experimental oncotherapeutics programs have been in place at major academic centres for over four decades. The emergence of molecular targeting agents and the recent introduction of immuno-oncology drugs have expanded the scope and eligibility for first-in-human trials. Improved understanding of tumor biology coupled with the ability to screen for tumor associated targets, as well as, genetic alterations have heralded the era of personalized (personalized or precision) cancer treatment. Molecular targeting agents with their improved tolerability and sustained responses compared to conventional cytotoxic chemotherapy have contributed to remarkable improvements in clinical outcomes Dramatic phase 1 observations of anti-tumor activity of novel molecules in the relapsed or refractory setting have ofen led to their investigation as monotherapy or in combinatorial strategies early in the course of cancer treatment. Studies have thus evolved from the traditional role of dose and toxicity-fnding studies to innovative enrichment study designs which match patients with study agents, thus increasing the potential of clinical efcacy, even in the early dose escalation setting.
Understanding the “Conflict of Interest
Authors: Dhingra Dr. Vandana Kumar
Published: May 2021

According to Wikipedia, ‘Çonflict of interest’ is a set of circumstances that creates a risk that professional judgement or actions regarding a primary interest will be unduly influenced by a secondary interest' [1]. It may be broadly described as conditions which may influence one’s judgement in a situation (primary interest) for some other gain (secondary interest), this may be financial or non-financial . It is of importance to understand that having a secondary gain is not wrong but these gains should not be illegal. This pertains to delivery of patient care, teaching and research in the medical profession.
Molecular characterization of ESBL- producing uropathogenic Escherichia coli recovered from urine samples of patients attending a University Teaching hospital in Nigeria
Authors: Adekanmbi Abimbola Olumide , Usidamen Sandra , Onilude Anthony Abiodun
Published: May 2021

Infection of the urinary tract ranks as one of the most common infections affecting people worldwide and its treatment is made complicated by the rising incidence of antibiotic resistance. This study aimed to detect extended spectrum beta-lactamase (ESBL) genes and antibiotic resistance profile of uropathogenic Escherichia coli (E. coli) recovered from patients attending a University Teaching hospital in Nigeria. Uropathogenic E. coli isolates were obtained from the culture collection of Department of Microbiology and Parasitology of the University Teaching hospital for a period of four months (October 2019–January, 2020). Antibiotic susceptibility testing was done using the disc diffusion method while phenotypic ESBL production was detected using double disc synergy test (DDST). Detection of β-lactamase genes was done using Real-Time PCR. Forty-nine E. coli isolates were recovered from 120 urine samples, with 24 (49%) being ESBL positive. The resistance to antibiotics in the ESBL producers was: ciprofloxacin (100%), cefotaxime (100%), cefpodoxime (100%), tetracycline (95.7%), ceftazidime (56.7%), amoxicillin-clavulanate (50%), gentamicin (33.3%), and imipenem (0%). All the ESBL producers carried blaTEM, blaCTX-M-1 and blaCTX-M-9, 75% (18/24) carried blaSHV, while blaCTX-M-2, blaCTX-M-8 and blaCTX-M-25 groups were detected in 20.8% (5/24) of the isolates. There was co-occurrence of CTX-M, SHV and TEM β-lactamases in 79.2% (19/24) isolates, while five isolates (20.8%) co-harbored blaCTX-M and blaTEM. This study showed a high level of multidrug resistance and ESBL gene carriage in uropathogenic E. coli obtained in this study, suggesting a likely review of therapeutic options in the treatment of UTI to clamp down on the rising cases of antibiotic resistance.
The effect of varying specimens’ printing angles to the bed surface on the tensile strength of 3D-printed 17-4PH stainless-steels via metal FFF additive manufacturing
Authors: Alkindi Tawaddod , Alyammahi Mozah , Susantyoko Rahmat Agung , Atatreh Saleh
Published: May 2021

We fabricated 17-4PH stainless-steel specimens via Fused Filament Fabrication (metal FFF). Then, we studied the effect of varying specimens’ printing angles to the bed surface (part orientation) by analyzing the tensile test and scanning electron microscopy results. We found anisotropy, where specimens printed at 90° exhibited the lowest tensile-stress-at-maximum-load of 440.15 MPa and elongation-at-break of 0.83%, compared to specimens printed at 0° of 947.26 MPa and 2.98%, respectively. We recommend printing angles from 0° to 10° to achieve optimum tensile strengths. This study is significant in ensuring quality for the deployment and scale-up of spare-part production via metal FFF.

Graphic abstract
An investigation of the effect of thermoplastic additives in asphalt concrete mixtures on the properties of different types of asphalt concrete
Authors: Zhdaniuk Valeriy , Volovyk Oleksandr , Kostin Dmytro , Lisovin Sergey
Published: May 2021

The effect of modification of asphalt concrete mixtures of different grain sizes with “Ric-Polycell” (Ukraine) and “Duroflex®-SMA” thermoplastic polymers (Germany), which were added directly to the asphalt mixer during their preparation, on the properties of asphalt concrete was studied. It is confirmed that it is more expedient to use stone mastic asphalt concretes with a larger size of mineral crushed stone grains on high-traffic roads, as they are more rutting-resistant compared to asphalt concretes with smaller size and content of crushed stone grains.
The effect of the temperature of preparation and thermostating of asphalt concrete mixtures modified with the investigated thermoplastics on the compressive strength of asphalt concrete at a temperature of 50 °С, which were made of the studied mixtures, was investigated. It was found that the maximum possible temperatures of preparation and thermostating of asphalt concrete mixes provide a more complete modification.
The effect of the content of thermoplastic polymers in the composition of asphalt concrete mixtures on the properties and rutting resistance of fine-grained asphalt concrete, as well as stone mastic asphalt concrete, was studied. It was found that adding the “Ric-Polycell” polymer in the amount of 1.5 % and 3 % by weight of bitumen in the composition of the studied asphalt mixtures in the asphalt mixer during their preparation increases the rutting resistance of asphalt concrete under the studied conditions by 2.52–3.86 times. Modification of asphalt concrete mixtures with the “Duroflex®-SMA” additive in the amount of 0.3 % and 0.6 % by weight of the aggregate by a similar technology also allows increasing the rutting resistance of the obtained asphalt concrete by 1.86–3.16 times. Using these modifiers in the future will have a positive effect on the service life of the entire pavement structure
Development of a special cell for optical and electrochemical measurements using 3D printing and modern electronic base
Authors: Kotok Valerii , Kovalenko Vadym
Published: May 2021

A special design of the measuring cell was proposed, which makes it possible to determine the optical and electrochemical characteristics of thin-film electrochromic electrodes simultaneously. Also, the proposed cell provides constant temperature control using a small-sized thermostating unit built on Peltier elements and digital boards of W1209 thermostats.
The cell was made using 3D printing with ABS plastic by the fused deposition method (FDM), followed by a sealing stage using a solution of polymethyl methacrylate dissolved in dichloroethane.
In the course of the research, the use of a green laser with a wavelength of 520 nm was substantiated. Separately, the linearity of optical readings, the dependence of the indicators of the optical characteristics measurement system on temperature, as well as the uniformity of electrolyte heating in the cell, were studied. In addition, the pattern of the electric field was determined, which was an indicator of the uniformity of the current density distribution on the measured electrode.
The obtained dependences made it possible to assert that the characteristics of the cell and the measuring system as a whole are suitable for the stated research purposes.
It was also shown that the cost of the cell, together with the optical measuring system and the constant temperature control system, is more than two times cheaper than simple electrochemical cells offered by manufacturers.
The proposed algorithm for the development of the cell design, the approach to the selection of components, as well as the given technical details, allow us to manufacture measuring equipment for the specific goals of the researcher. In this case, the given schematic, structural, and hardware solutions can be used separately from each other
A comprehensive procedure for estimating the stressed-strained state of a reinforced concrete bridge under the action of variable environmental temperatures
Authors: Kovalchuk Vitalii , Onyshchenko Artur , Fedorenko Olexander , Habrel Mykola , Parneta Bogdan , Voznyak Oleh , Markul Ruslan , Parneta Mariana , Rybak Roman
Published: May 2021

This paper reports the full-scale experimental measurements of temperature distribution over the surfaces of bridges' steel-concrete beams under the influence of positive and negative ambient temperatures. It has been established that the temperature is distributed unevenly along the vertical direction of a bridge's steel-concrete beam.
It was found that the metal beam accepted higher temperature values. The maximum registered temperature difference between a metal beam and a reinforced concrete slab at positive ambient temperatures was +9.0 °C, and the minimum temperature difference was −2.1 °C.
The mathematical models for calculating a temperature field and a thermally strained state of bridges' steel-concrete beams under the influence of variable climatic temperature changes in the environment have been improved, taking into consideration the uneven temperature distribution across a bridge's reinforced concrete beam. The possibility has been established to consider a one-dimensional problem or to apply the three-dimensional estimated problem schemes as the estimation schemes for determining the thermo-elastic state of reinforced concrete bridges.
The temperature field and the stressed state of bridges' reinforced concrete beams were determined. It was found that the maximum stresses arise at the place where a metal beam meets a reinforced concrete slab. These stresses amount to 73.4 MPa at positive ambient temperatures, and 69.3 MPa at negative ambient temperatures.
The amount of stresses is up to 35 % of the permissible stress values. The overall stressed-strained state of a bridge's reinforced concrete beams should be assessed at the joint action of temperature-induced climatic influences and loads from moving vehicles
Development of estimation and forecasting method in intelligent decision support systems
Authors: Romanenko Іgor , Golovanov Andrii , Khoma Vitalii , Shyshatskyi Andrii , Demchenko Yevhen , Shabanova-Kushnarenko Lyubov , Ivakhnenko Tetiana , Prokopenko Oleksandr , Havaliukh Oleh , Stupak Dmitrо
Published: May 2021

The method of estimation and forecasting in intelligent decision support systems is developed. The essence of the proposed method is the ability to analyze the current state of the object under analysis and the possibility of short-term forecasting of the object state. The possibility of objective and complete analysis is achieved through the use of improved fuzzy temporal models of the object state, an improved procedure for forecasting the object state and an improved procedure for training evolving artificial neural networks. The concepts of a fuzzy cognitive model, in contrast to the known fuzzy cognitive models, are connected by subsets of fuzzy influence degrees, arranged in chronological order, taking into account the time lags of the corresponding components of the multidimensional time series. This method is based on fuzzy temporal models and evolving artificial neural networks. The peculiarity of this method is the ability to take into account the type of a priori uncertainty about the state of the analyzed object (full awareness of the object state, partial awareness of the object state and complete uncertainty about the object state). The ability to clarify information about the state of the monitored object is achieved through the use of an advanced training procedure. It consists in training the synaptic weights of the artificial neural network, the type and parameters of the membership function, as well as the architecture of individual elements and the architecture of the artificial neural network as a whole. The object state forecasting procedure allows conducting multidimensional analysis, consideration and indirect influence of all components of a multidimensional time series with different time shifts relative to each other under uncertainty.
Developing the minimization of a polynomial normal form of boolean functions by the method of figurative transformations
Authors: Solomko Mykhailo , Batyshkina Iuliia , Khomiuk Nataliia , Ivashchuk Yakiv , Shevtsova Natalia
Published: May 2021

This paper reports a study that has established the possibility of improving the effectiveness of the method of figurative transformations in order to minimize Boolean functions on the Reed-Muller basis. Such potential prospects in the analytical method have been identified as a sequence in the procedure of inserting the same conjuncterms of polynomial functions followed by the operation of super-gluing the variables.
The extension of the method of figurative transformations to the process of simplifying the functions of the polynomial basis involved the developed algebra in terms of the rules for simplifying functions in the Reed-Muller basis. It was established that the simplification of Boolean functions of the polynomial basis by a figurative transformation method is based on a flowchart with repetition, which is actually the truth table of the predefined function. This is a sufficient resource to minimize functions that makes it possible not to refer to such auxiliary objects as Karnaugh maps, Weich charts, cubes, etc.
A perfect normal form of the polynomial basis functions can be represented by binary sets or a matrix that would represent the terms of the functions and the addition operation by module two for them.
The experimental study has confirmed that the method of figurative transformations that employs the systems of 2-(n, b)-design, and 2-(n, x/b)-design in the first matrix improves the efficiency of minimizing Boolean functions. That also simplifies the procedure for finding a minimum function on the Reed-Muller basis. Compared to analogs, this makes it possible to enhance the performance of minimizing Boolean functions by 100‒200 %.
There is reason to assert the possibility of improving the efficiency of minimizing Boolean functions in the Reed-Muller basis by a method of figurative transformations. This is ensured by using more complex algorithms to simplify logical expressions involving a procedure of inserting the same function terms in the Reed-Muller basis, followed by the operation of super-gluing the variables.
Determination of the regularities of the soil punching process by the working body with the asymetric tip
Authors: Kravets Svyatoslav , Suponyev Vladimir , Shevchenko Valery , Yefymenko Alexander , Ragulin Vitaliy
Published: May 2021

The presence of analytical dependencies describing the process of static soil puncture by a working body with a conical asymmetric tip is necessary to create installations with the ability to control the trajectory of the soil puncture.
The paper considers the features of the process of interaction of an asymmetric conical tip with the ground. Analytical relationships were obtained to determine its reactions during a static puncture, the deviation of the head trajectory from a straight line, to determine the size of the soil compaction zone and the magnitude of the destructive force that acts on adjacent communications and other underground objects. It was found that with an increase in the value of the displacement of the top of the cone, for example, from its axis from 0.02 m to 0.08 m with a borehole diameter of 0.2 m, the value of soil resistance increases almost four times. The greatest resistance is achieved when piercing a hard sandy sand.
It was found that with an increase in the displacement of the tip of the tip cone, the deviation of the trajectory increases. The piercing head achieves the greatest deviation from the straight trajectory of movement with a sharper cone and a greater asymmetric deviation of its top, and, for example, in hard sandy loam can be up to 0.17 m with a span of 10 m.
It was found that the size of the soil destruction zone will be almost 1.8 times larger than the tip in the form of a symmetrical cone and reaches from 8 to 12 borehole diameters, depending on the type of soil. The maximum pressure on adjacent objects can reach from 0.06 MPa in hard-plastic clay to 0.09 MPa in hard sandy loam.
The calculated dependences obtained for determining the power and technological parameters depending on the geometric dimensions of the asymmetric tip of the working body can be used to create installations with a controlled static puncture for use in the most common soil conditions.
Optimization of the HACCP safety control system for collagen hydrolysate production by implementing the FMEA model
Authors: Kazhymurat Assemay , Uazhanova Raushangul , Tlevlesova Dinara , Zhexenbay Nurshash , Tungyshbayeva Ulbala , Mannino Saverio
Published: May 2021

This study was carried out to determine the impact of the HACCP control system on the safety of the final products of collagen hydrolysate production. The object of the study was equine connective tissue. Using the FMEA model, established by a three-factor assessment of the risk priority number (RPN), critical control points (CCP) in the processes of hydrolysis, inactivation of the enzyme preparation, drying and storage were identified. For two CCP, measures for continuous monitoring were identified, and critical limits were developed. For CCT 1, the calculation of optimal fermentation processes using a mathematical model for the hydrolysis of raw materials is given. The optimal values of the Neutrase enzyme, providing a maximum content of water-soluble proteins of 55.0 mg/cm3, were determined: T=37 °C, dosage 5 Pa/g, t=210 min.

For CCP 2, to avoid protein denaturation during hydrolysis, a critical limit was developed by determining the heat inactivation point and optimum temperature. Experimental analyses show that the inactivation point of the Neutrase enzyme, estimated by the rate of FTN accumulation, which has 20 % at 60 °C, is reached at the 11th minute.

As a result of the study, the effect of enzyme preparations on the safety of collagen hydrolysate was also determined. The result confirms that the Neutrase enzyme preparation had a positive effect on all safety indicators compared to the Trypsin enzyme. The optimal parameters for reducing microbiological indicators, pesticides, antibiotic and toxic metals are: T=40 °C, duration 210 min, dosage of the Neutrase enzyme 5 units/Pa.

The results can be used in collagen hydrolysate production to better ensure the quality and safety of the final product
Conhecimento e autoconfiança de Agentes Comunitários de Saúde sobre Primeiros Socorros e Parada cardiopulmonar
Authors:   Universidade Estadual Vale do Acaraú, Bezerra Martins Débora Maria , Sousa Albuquerque Brandão Maria Girlane , de Sousa Araújo Francisca Drenalina , Camelo Albano Livia Maria , de Sousa Ávila Erilandy , Galindo Neto Nelson Miguel , Moreira Barros Lívia
Published: May 2021

Introdução: Os Agentes Comunitários de Saúde são uma categoria profissional no Brasil que se encontram contato direto e diário com os usuários na comunidade e possuem maior probabilidade de se deparar com situações de emergência ou primeiros socorros. Objetivo: Avaliar o conhecimento e autoconfiança de Agentes Comunitários de Saúde sobre Primeiros Socorros e Parada cardiopulmonar. Materiais e Método: Estudo descritivo e quantitativo, realizado de junho a outubro de 2018, em 22 Centros de Saúde da Família de município do Ceará, Brasil, com 186 Agentes Comunitários de Saúde, divididos em dois grupos: aqueles já tinham treinamento sobre a temática e os que não possuíam treinamento. Na coleta de dados foi aplicado questionário com: 1) caracterização da amostra; 2) Questões sobre Parada Cardiopulmonar; 3) Questões sobre primeiros socorros; 4) Escala de autoconfiança. Resultados: Houve diferença significante entre os grupos nas questões de conhecimento em quatro itens, nas questões sobre definição de PCR, verificação da responsividade de uma vítima desacordada, sequência para o posicionamento das mãos e braços na ressuscitação cardiopulmonar (RCP) e momento de troca dos socorristas. Nos primeiros socorros, houve diferença estatisticamente significante em quatro itens, nas questões de primeira conduta no caso de precisar atender uma vítima em situação de urgência, cuidados durante uma crise de convulsão, condutas com vítimas de afogamento e cuidados com bebê engasgado. Ambos os grupos apresentaram autoconfiança baixa para intervir em situações de emergências cardíacas, neurológicas e respiratórias. Conclusão: Os achados da pesquisa apontam déficit de conhecimento dos agentes comunitários de saúde para atuar frente a parada Cardiopulmonar e em situações de primeiros socorros, associado à baixa autoconfiança para intervir em situações de emergências.
Notícias falsas em tempos de pandemia pelo novo coronavírus: uma análise documental
Authors:   Universidad Federal Do Piaui, Santos Alencar Nadyelle Elias , Fernandes Lima Francisca Fabiana , Teles de Oliveira Gouveia Marcia , Freitas da Silva Grazielle Roberta
Published: May 2021

Introdução: A infodemia, ou fluxo elevado de informações, apresenta comportamento similar aos vírus, disseminam-se de pessoa a pessoa e representam um novo desafio às autoridades de saúde. Objetiva-se analisar as notícias falsas veiculadas no contexto da pandemia pelo novo coronavírus. Materiais e métodos: Pesquisa documental realizada com base no portal de notícias do Ministério da Saúde do Brasil intitulado "Saúde sem Fake News". Foram identificadas as publicações ocorridas de dezembro/2019 a março/2020, por meio das seguintes palavras-chave: coronavírus e COVID-19. Para a apreciação dos dados, foi adotada a análise de conteúdo proposta por Bardin. Resultados: Foram identificadas 66 publicações, com o total de 92 fake news. A análise revelou as características comuns às fake news, dentre elas: manchetes e imagens chamativas, dados alarmantes e disseminação cíclica. Além disso, as mídias sociais despontaram como importante via de disseminação e, para conferir efeito de verdade ao dito, a atribuição da autoria a órgãos ou profissionais da saúde foi comum. As notícias foram categorizadas em seis grupos temáticos: métodos para prevenção (32,6%) e história natural da doença (28,2%) foram os mais frequentes. Discussão: Observa-se o interesse crescente por temas relacionados à disseminação de informações sobre o novo coronavírus e as investigações ao redor do mundo destacam a importância da atuação do Governo e dos órgãos da saúde na identificação e combate às notícias falsas. Conclusões: As fake news relacionadas ao novo coronavírus ameaçam a saúde individual e coletiva, abordam temáticas diversas e apresentam potencial de dano à saúde física e mental.
A RECEPÇÃO DE PIERRE BOURDIEU NA SOCIOLOGIA DA EDUCAÇÃO BRASILEIRA
Authors: Oliveira Amurabi , Silva Camila Ferreira da
Published: May 2021

Resumo O alcance e a envergadura dos trabalhos de Pierre Bourdieu são atestados ao redor do mundo desde suas primeiras publicações na década de 1960, passando pelas traduções que suas obras receberam ao longo do tempo e também pela ampla apropriação que seus constructos teóricos, conceituais e metodológicos têm demonstrado em diferentes áreas do conhecimento por mais de cinco décadas. O presente artigo elege a sociologia da educação brasileira como espaço acadêmico privilegiado para analisar a recepção da obra de Bourdieu no Brasil, ocupando-se das condições de possibilidade da introdução e difusão de seu pensamento e das leituras da obra desse sociólogo que passaram a ser realizadas no país.