bluuebunny/crossref_metadata_2025 huggingface dataset:
Vertical root fracture diagnosis in endodontically treated teeth
Authors: Gadzhula N. G. , Fedyk T. V. , Goray M. A. , Yasko V. V.
Published: April 2022

Annotation. Timely diagnosis of vertical root fractures is a big challenge to dentists, because there are no specific clinical signs, symptoms and X-ray features. The aim of the research is to study clinical cases of vertical root fractures in endodontically treated teeth and to carry out analysis the methods of their diagnosis, clinical features and radiological characteristics. In patients aged 40-65 years, 34 clinical cases of vertical root fracture are considered. The main and additional methods of patients’ examination are analyzed. The statistical calculation of the obtained results is performed by the method of variation statistics with the determination of the Student’s t-test using computer programs Microsoft® Excel 2017 and “Statistica 6.1”. Clinical symptoms and abnormal findings during examination were recorded but not subjected to statistical analysis. Clinical examination revealed periodontal swelling or abscess in 6 patients, isolated narrow and deep periodontal pocket in 24 patients, low localized fistula in 9 patients. Radiological results: only in 6 clinical cases a vertical fracture line was observed on intraoral X-ray images; in 30 cases the destruction of bone tissue in the periapical area, mainly in the halo-type radiolucency was determined; in 4 cases no pathological changes in periapical bone tissue were revealed. Vertical root fracture was confirmed by muco-periosteal flap detachment in all cases. It has been established that a number of signs, namely: isolated deep narrow periodontal pocket; coronally located fistula; characteristic bone destruction (J-shaped or “halo” radiolucency) on the radiograph indicate the likelihood of vertical root fracture. Signs of fenestration of the bone adjacent to the fractured root and visualization of the fracture line after mucoperiosteal flap surgery are pathognomonic.
Optimization of early markers for the diagnosis of preeclampsia on the background of metabolic syndrome
Authors: Franchuk U. Ya. , Khmil S. V. , Malanchuk L. M. , Malanchyn I. M.
Published: April 2022

Annotation. Preeclampsia remains a mysterious puzzle for clinicians and researchers who have been uncovering it for decades. The search for new modern diagnostic markers for the possibility of early prevention of this complication will facilitate the course of pregnancy and childbirth. Preeclampsia can affect 2-8% of all pregnancies. The study of angiogenic biomarkers to stratify the risk of disease is the aim of our study. Patients are divided into groups due to the severity of preeclampsia. Group I included 26 pregnant women with moderate preeclampsia, diastolic blood pressure was up to 90 m Hg, to group II – 20 pregnant women with moderate preeclampsia, the level of diastolic pressure was up to 99 m Hg. The third group included pregnant women in whom the physiological course of pregnancy without complications and concomitant extragenital pathology. Inhibin A levels were determined using a Beckmann Coulter analyzer and test system (Germany); ELISA Testkit, Access-Inhibin A Kit by Beckmann Coulter, the concentration of vitamin D in the serum of patients was determined using an analyzer and test system Immulite (Siemens AG, Germany). Statistical analysis of the obtained results was performed minus the mean value (M) and the standard error of the mean value (m). Qualitative indicators are presented in the form of %. Comparison of quantitative indicators with normal distribution was performed by Student’s t test (p<0.05), and with abnormal distribution in unrelated samples – using Mann-Whitney test (U test), comparison of relative values – using χ2 (chi) -square). A significant relationship (p=0.041) was found between inhibin A levels and the occurrence of preeclampsia. Vitamin D deficiency (24.5±1.01 ng/ml) was also found in women in the study groups. The level of placental growth factor in all women in the first trimester of pregnancy was 45.93±11.74 pg/ml, which corresponds to normal values. The mean level of insulin-like growth factor was reduced (120.87±4.12 ng/ml) compared with the control group (224.1±6.24 ng/ml). Thus, increased inhibin A, decreased IGF, and vitamin D deficiency may be a marker for a patient at risk for preeclampsia.
Personnel resources as a component of ensuring the quality and availability of dental care for the population of Ukraine
Authors: Grohotov V. A. , Orlova N. M.
Published: April 2022

Annotation. Providing high-quality and affordable dental care to the population requires monitoring the medical staff of the dental service. Purpose: to analyze the state and problems of human resources of the dental service of the system of the Ministry of Health of Ukraine in 2010-2020. Using the medical-statistical method, the statistical data of the Center for Medical Statistics of the Ministry of Health of Ukraine were analyzed. It is established that during 2010-2020 in Ukraine the process of restructuring the network of dental institutions continues. As a result, the number of communal/state institutions in the system of the Ministry of Health of Ukraine has decreased and the number of private institutions has increased rapidly. This process causes the outflow of dentists from the communal to the private sector of dentistry. During the observation period, the number of dentists in the institutions of the system of the Ministry of Health of Ukraine decreased by 40.9% (from 21,313 in 2010 to 12,601 individuals in 2020). The number of dentists per 10 000 population in the system of the Ministry of Health decreased by 34.9% (from 4.67 in 2010 to 3.04 in 2020). The staffing of full-time positions of dentists in the institutions of the Ministry of Health decreased over the observation period from 93.3% to 86.9%. Dentists of the system of the Ministry of Health of Ukraine are highly qualified to provide the population with quality dental care: 73.3% of them are certified (67.2% among doctors of all specialties), among the certified half (49.7%) have the highest, and a third (32.9%) – the first qualification category. Dentists in the institutions of the Ministry of Health of Ukraine continue to provide the bulk of dental care to the population of the country, serving the vast majority (63.1%) of all dental visits and have 2.2-2.9 times higher average annual workload than their counterparts in private sector of dental care. Solving the problem of providing the population of Ukraine with affordable and high-quality dental care requires the development of an effective personnel policy in the field of dental health, aimed at maintaining the human resources of the communal/state sector of dentistry.
Laparoscopic retropubic prostatectomy in the surgical treatment of benign prostatic hyperplasia (literature review)
Authors: Gorovyi V. I. , Shaprynskyi V. O. , Baralo I. V. , Kapshuk O. M. , Moraru-Burlesku R.P. , Suleimanova V. G. , Horovyi O. V. , Dovgan I. I. , Hural D. M.
Published: April 2022

Annotation. The MEDLINE/PubMed database was searched for all original articles published between 2011 and 2022 analyzing the incidence, prevalence, complications and surgical treatment of benign prostatic hyperplasia using laparoscopic prostatectomy (including retropubic interventions) and open retropubic prostatectomy to compare advantages and disadvantages of the both approaches. It was found that transperitoneal approach was used in 104 (12.4%) patients, extraperitoneal – 739 (87.6%). Complications of the I degree according to Clavien-Dindo inpatient period were observed in 4 (0.5%) patients; complications of the II degree – 10 (1.2%), complications of the IIIa degree – 5 (0.6%). Complications of the III, IV and V degrees were not identified, mortality was absent. Complications of the I degree according to Clavien-Dindo after discharge from the hospital (up to 90 days of observation) were discovered in 42 (5%) patients, complications of the II degree – in 13 (0.6%). Laparoscopic prostatectomies had a low percentage of intraoperative blood transfusions (1.2%), strictures of the urethra/bladder neck (0.35%) and fistula formation (0.12%). No wound infection was observed in any patient. Laparoscopic prostatectomies have the significant advantages over open prostatectomies, and therefore they should be more widely used in Ukraine.
Kulturális adatelemzés – bevezetés és önéletrajz
Authors: Király Péter
Published: April 2022

Lev Manovich. Cultural analytics. Cambridge, Massachussetts–London, England: The MIT Press, 2020.https://doi.org/10.7551/mitpress/11214.001.0001. 318 oldal. ISBN 9780262037105, e-ISBN 9780262360647
INNOVATIVE TEACHING COURSES IN BACHELOR’S PROGRAM OF MEDICAL REHABILITATION
Authors: Giorgi Parulava  , Alexander Egoyan  , Giovanni Roviello
Published: April 2022

The aim of our research is to introduce new innovative training courses in theprogram of physical medicine and rehabilitation, taking into account the results of statistical analysis of survey data among students andundergraduates of the Faculty of Physical Medicine and Rehabilitation of the University of Sports. 230 students, 48 graduates and 6 employers were interviewed. Based on the analysis of the obtained results, we consider it expedient to add the following teaching courses to the program of medicine and rehabilitation: ″Modern Technologies in Motion Biomechanics″, ″Biotechnological Basis of Rehabilitation″ and ″Psychosocial Rehabilitation″.The first one will teach students how to use sensor and video-computer technologies for qualitative and quantitative movement analysis, the second one will furnish the students with recent insights into the biotechnological basis of rehabilitation and the third one will teach students how to work with people having mental disabilities.
Gangguan Berbahasa pada Anak Penderita Hidrosefalus
Authors: Kadafi Tito Tri
Published: April 2022

Abstract

This research was conducted by seeing language disorder in child with hydrocephalus, whose subjects were hydrocephalus sufferers from birth. Using qualitative methods, as well as data collection techniques through observation, literature review, and interviews, this study seeks to identify the causes of language disorders experienced by VC (respondent). The results showed a cognitive effect due to hydrocephalus conditions, and imperfect use of articulatory tools in speech, which caused the inability of VC to pronounce the phonemes / s /, / r /, / l /, and / z /. Another influence that also causes language disorders is the passivity of social interactions due to limited interaction between respondents and peers in the neighborhood where he live.

 
Abstrak

Penelitian ini dilakukan dengan meneliti gangguan berbahasa pada anak penderita hidrosefalus, yang subjeknya merupakan penderita hidrosefalus sejak lahir. Menggunakan metode kualitatif, serta teknik pengumpulan data melalui observasi, telaah pustaka, dan wawancara penelitian ini berupaya untuk mengidentifikasi penyebab gangguan berbahasa yang dialami VC (responden). Hasil penelitian menunjukkan adanya pengaruh kognitif karena kondisi hidrosefalus, dan ketidaksempurnaan penggunaan alat artikulatoris dalam tuturan, yang menyebabkan ketidakmampuan VC dalam mengujarkan fonem /s/, /r/, /l/, dan/z/. pengaruh lain yang juga menyebabkan gangguan berbahasa ialah pasifnya pergaulan karena interaksi terbatas antara responden dengan rekan sebaya di sekitar lingkungan tempat tinggalnya.
Jargon Bahasa Berdasarkan Model Fungsional Speaking di Kalangan Komunitas Dakwah : Kajian Sosiolinguistik
Authors: Safitri Vivian Nur , Mujianto Gigit
Published: April 2022

Abstract
This study aims to describe the form of jargon language variations studied based on the SPEAKING component. The approach in this research is a qualitative approach. The data in this study include a collection of vocabulary used in conversational interactions in the Islamic da'wah community, both directly and indirectly (online) and carried out by the observation process. The data source in this study is oral or written speech of members of the Islamic da'wah community in universities. The research data collection was carried out through listening and observation techniques which were accompanied by data collection instruments through written techniques. Data analysis technique is done by sorting and correlating jargon language variation data according to the SPEAKING component model then plotting the data into tables and then classified according to the form and results of data analysis. The results showed (1) Classification of jargon language variation data based on SPEAKING components (2) Factors causing jargon language variations, (3) Characteristics of jargon, (4) Functional models of SPEAKING, and (5) Variations in jargon language of dawa community.
 
Abstrak
Penelitian ini bertujuan untuk mendeskripsikan bentuk variasi bahasa jargon yang dikaji berdasarkan model fungsional SPEAKING. Pendekatan dalam penelitian ini adalah pendekatan kualitatif. Data dalam penelitian ini meliputi kumpulan kosakata yang digunakan pada interaksi percakapan di komunitas dakwah Islam, baik secararing maupun daring dilakukan dengan proses observasi. Sumber data dalam penelitian ini adalah tutur lisan atau tulis anggota komunitas dakwah Islam yang ada di perguruan tinggi. Pengumpulan data penelitian dilakukan melalui teknik simak dan observasi yang disertai instrumen penjaringan data melalui teknik tulis. Teknik analisis data dilakukan dengan memilah dan mengkorelasikan data variasi bahasa jargon sesuai dengan model model fungsional SPEAKING kemudian memplotkan data-data ke dalam tabel kemudian diklasifikasikan sesuai bentuk dan hasil analisis data. Hasil penelitian menunjukkan (1) Klasifikasi bahasa jargon yang meliputi latar tempat, penutur, tujuan, acuan, perilaku, saluran tutur, interaksi, dan jenis tutur pada SPEAKING,  (2) Faktor penyebab terjadinya variasi bahasa jargon, (3) Ciri-ciri jargon, (4) Model fungsional SPEAKING, dan (5) Variasi bahasa jargon komunitas dakwah.
Quantification of groundwater storage variation in Himalayan & Peninsular River basins correlating with land deformation effects observed at different Indian cities
Authors: SARKAR Tandrila , KARUNAKALAGE Anuradha , KANNAUJIYA Suresh , CHAGANTI Charan
Published: April 2022

Groundwater is a significant resource that supports almost one-fifth population globally, but has been is diminishing at an alarming rate in recent years. To delve into this objective more thoroughly, we calculated interannual (2002–2020) GWS (per grid) distribution using GRACE & GRACE-FO (CSR-M, JPL-M and SH) Level 3 RL06 datasets in seven Indian river basins and found comparatively higher negative trends (−20.10 ± 1.81 to −8.60 ± 1.52 mm/yr) in Basin 1–4 than in Basin 5–7 (−7.11 ± 0.64 to −0.76 ± 0.47 mm/yr). After comparing the Groundwater Storage (GWS) results with the CHIRPS (Climate Hazards Group Infrared Precipitation with Stations) derived SPI (Standardized Precipitation Index) drought index, we found that GWS exhausts analogously in the same period (2005–2020) when SPI values show improvement (∼1.89–2), indicating towards wet condition. Subsequently, the GWSA time series is decomposed using the STL (Seasonal Trend Decomposition) (LOESS Regression) approach to monitor long-term groundwater fluctuation. The long term GWS rate (mm/yr) derived from three GRACE & GRACE-FO solutions vary from −20.3 ± 5.52 to −13.19 ± 3.28 and the GWS mass rate (km3/yr) lie in range of −15.17 ± 4.18 to −1.67 ± 0.49 for basins 1–3. Simultaneously, in basin 4–7 the GWS rate observed is −8.56 ± 8.03 to −0.58 ± 7.04 mm/yr, and the GWS mass rate differs by −1.71 ± 0.64$ to −0.26 ± 3.19 km3/yr. The deseasonalized GWS estimation (2002–2020) states that Himalayan River basins 1,2,3 exhibit high GWS mass loss (−260 to −35.12 km3), with Basin 2 being the highest (−260 km3). Whereas the Peninsular River basin 4,6,7 gives moderate mass loss value from −26.72 to −23.58 km3. And in River basin 5, the GWS mass loss observed is the lowest, with a value of −8 km3.
Microsurgical anatomy and insular connectivity of the cerebral opercula
Authors: Demirtaş Oğuz Kağan , Güngör Abuzer , Çeltikçi Pınar , Çeltikçi Emrah , Munoz-Gualan Alberth Patricio , Doğulu Fikret Hüseyin , Türe Uğur
Published: April 2022

OBJECTIVE

Radiological, anatomical, and electrophysiological studies have shown the insula and cerebral opercula to have extremely high functionality. Because of this complexity, interventions in this region cause higher morbidity compared to those in other areas of the brain. In most early studies of the insula and white matter pathways, insular dissection was begun after the opercula were removed. In this study, the authors examined the insula and deep white matter pathways to evaluate the insula as a whole with the surrounding opercula.

METHODS

Twenty formalin-fixed adult cerebral hemispheres were studied using fiber microdissection techniques and examination of sectional anatomy. Dissections were performed from lateral to medial, medial to lateral, inferior to superior, and superior to inferior. A silicone brain model was used to show the normal gyral anatomy. Sections and fibers found at every stage of dissection were photographed with a professional camera. MRI tractography studies were used to aid understanding of the dissections.

RESULTS

The relationships between the insula and cerebral opercula were investigated in detail through multiple dissections and sections. The relationship of the extreme and external capsules with the surrounding opercula and the fronto-occipital fasciculus with the fronto-orbital operculum was demonstrated. These findings were correlated with the tractography studies. Fibers of the extreme capsule connect the medial aspect of the opercula with the insula through the peri-insular sulcus. Medial to lateral dissections were followed with the removal of the central core structures, and in the last step, the medial surface of the cerebral opercula was evaluated in detail.

CONCLUSIONS

This anatomical study clarifies our understanding of the insula and cerebral opercula, which have complex anatomical and functional networks. This study also brings a new perspective to the connection of the insula and cerebral opercula via the extreme and external capsules.
Effects of local intraoperative epidural use of triamcinolone acetonide–soaked Gelfoam on postoperative outcomes in patients undergoing posterolateral lumbar spinal fusion surgery: a randomized, placebo-controlled, double-blind trial
Authors: Tavanaei Roozbeh , Ahmadi Pooria , Malekipour Bahador , Herfedoust Biazar Bijan , Keikhaee Mohsen , Oraii Yazdani Kaveh , Zali Alireza , Oraee-Yazdani Saeed
Published: April 2022

OBJECTIVE

Prior evidence has supported the use of local intraoperative epidural steroids in lumbar discectomy for improvements in postoperative pain and outcomes. However, currently there is a paucity of data regarding the efficacy of local epidural steroids in spinal fusion procedures. The present investigation aimed to evaluate the impact of local epidural administration of triamcinolone acetonide–soaked Gelfoam on postoperative pain and patient-reported outcomes in patients undergoing instrumented posterolateral lumbar spinal fusion.

METHODS

In this randomized, double-blind, placebo-controlled trial, patients were randomly divided into two groups (treatment and control). Patients in the treatment group received a Gelfoam carrier soaked in 1 ml of triamcinolone acetonide (40 mg), which was placed over the nerve roots in the epidural space before the closure. Patients in the control group received a Gelfoam carrier soaked in normal saline in a similar fashion to the treatment group. Patients were followed up during their hospital stay and at 4 and 12 weeks postoperatively. The primary outcome measure was early postoperative visual analog scale (VAS) scores for pain both at rest and with movement.

RESULTS

A total of 100 patients were recruited in this study and were randomly allocated to the treatment or control group. No significant difference was found in baseline demographic, clinical, and surgical characteristics between the two groups. Postoperative VAS scores for pain both at rest and with movement were comparable between the treatment and control groups. Cumulative morphine consumption, length of hospital stay, and incidence of postoperative complications such as surgical site infection were also similar between the two groups. There was no significant difference in patient-reported outcomes including VAS scores for back and leg pain as well as the Oswestry Disability Index at 4 and 12 weeks postoperatively. The proportion of patients who achieved a minimum clinically important difference for patient-reported outcomes were also similar between the two groups.

CONCLUSIONS

In contrast to the existing literature on the beneficial use of local intraoperative epidural steroids in conventional lumbar discectomy, the present study did not demonstrate such significant efficacy for the use of local epidural steroids in instrumented posterolateral lumbar spinal fusion. However, there is still a lack of evidence in this regard and further high-quality clinical trials are required to evaluate the efficacy of local epidural steroids in this group of patients.
Optimal targeting of the anterior nucleus of the thalamus for epilepsy: a meta-analysis
Authors: Ilyas Adeel , Snyder Kathryn M. , Thomas Tessy M. , Tandon Nitin
Published: April 2022

OBJECTIVE

Deep brain stimulation (DBS) of the anterior nucleus of the thalamus (ANT) has been shown to be an effective therapeutic option for select patients with limbic epilepsy. However, the optimal target and electrode position for this indication remains undefined. Therefore, the objective of this systematic review and meta-analysis is to quantify the association between active contact location and outcomes across all published series of ANT DBS.

METHODS

A literature search using PRISMA criteria was performed to identify all studies that reported both active contact locations and outcomes of DBS in the ANT for epilepsy. Patient, disease, treatment, and outcome data were extracted for statistical analysis. Contact locations of responders (defined as ≥ 50% seizure reduction at last follow-up) versus nonresponders to DBS were analyzed on a common reference frame. Centers of mass, weighted by clinical response, were computed for the contacts in each cohort.

RESULTS

From 555 studies that were screened for review, a total of 7 studies comprising 162 patients met criteria for inclusion and were analyzed. Across the cohort, the mean duration of epilepsy was 23 years and the mean pre-DBS seizure frequency was 56 seizures per month. DBS electrodes were implanted using direct targeting in 5 studies (n = 62, 38% of patient cohort) via a transventricular electrode trajectory in 4 studies (n = 123, 76%). At the mean follow-up duration of 2.3 years, 56% of patients were considered responders. Active contacts of responders were 1.6 mm anterior (95% CI 1.5–1.6 mm, p < 0.001) compared to those of nonresponders and were adjacent to the mammillothalamic tract (MTT).

CONCLUSIONS

Accurate targeting of the ANT is crucial to successful DBS outcomes in epilepsy. These findings suggest that stimulation within the ANT subregions adjacent to the MTT improves outcomes.
Surgical outcomes of patients who fail to reach minimal clinically important differences: comparison of minimally invasive versus open transforaminal lumbar interbody fusion
Authors: Ayling Oliver G. S. , Rampersaud Y. Raja , Dandurand Charlotte , Yuan Po Hsiang (Shawn) , Ailon Tamir , Dea Nicolas , McIntosh Greg , Christie Sean D. , Abraham Edward , Bailey Christopher S. , Johnson Michael G. , Bouchard Jacques , Weber Michael H. , Paquet Jerome , Finkelstein Joel , Stratton Alexandra , Hall Hamilton , Manson Neil , Thomas Kenneth , Fisher Charles G.
Published: April 2022

OBJECTIVE

Treatment of degenerative lumbar diseases has been shown to be clinically effective with open transforaminal lumbar interbody fusion (O-TLIF) or minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF). Despite this, a substantial proportion of patients do not meet minimal clinically important differences (MCIDs) in patient-reported outcomes (PROs). The objectives of this study were to compare the proportions of patients who did not meet MCIDs after O-TLIF and MIS-TLIF and to determine potential clinical factors associated with failure to achieve MCID.

METHODS

The authors performed a retrospective analysis of consecutive patients who underwent O-TLIF or MIS-TLIF for lumbar degenerative disorders and had been prospectively enrolled in the Canadian Spine Outcomes and Research Network. The authors analyzed the Oswestry Disability Index (ODI) scores, physical and mental component summary scores of SF-12, numeric rating scale (NRS) scores for leg and back pain, and EQ-5D scores of the patients in each group who did not meet the MCID of ODI at 2 years postoperatively.

RESULTS

In this study, 38.8% (137 of 353) of patients in the O-TLIF cohort and 41.8% (51 of 122) of patients in the MIS-TLIF cohort did not meet the MCID of ODI at 2 years postoperatively (p = 0.59). Demographic variables and baseline PROs were similar between groups. There were improvements across the PROs of both groups through 2 years, and there were no differences in any PROs between the O-TLIF and MIS-TLIF cohorts. Multivariable logistic regression analysis demonstrated that higher baseline leg pain score (p = 0.017) and a diagnosis of spondylolisthesis (p = 0.0053) or degenerative disc disease (p = 0.022) were associated with achieving the MCID at 2 years after O-TLIF, whereas higher baseline leg pain score was associated with reaching the MCID after MIS-TLIF (p = 0.038).

CONCLUSIONS

Similar proportions of patients failed to reach the MCID of ODI at 2 years after O-TLIF or MIS-TLIF. Higher baseline leg pain score was predictive of achieving the MCID in both cohorts, whereas a diagnosis of spondylolisthesis or degenerative disc disease was predictive of reaching the MCID after O-TLIF. These data provide novel insights for patient counseling and suggest that either MIS-TLIF or O-TLIF does not overcome specific patient factors to mitigate clinical success or failure in terms of the intermediate-term PROs associated with 1- to 2-level lumbar fusion surgical procedures for degenerative pathologies.
Penanaman Nilai-Nilai Pancasila dalam Jamaah Kopdariyah
Authors: Hakim Sholihul , Mazid Sukron
Published: April 2022

Jamaah Kopdariyah adalah sebuah komunitas lintas iman, pemuda dan budaya. Komunitas ini selalu mengadakan acara kopi darat mengenai isu-isu aktual yang sedang dialami bangsa Indonesia, baik dari agama, politik, ekonomi, dan sosial budaya. Hal ini sebagai bukti bahwa komunitas Jamaah Kopdariyah sangat peduli kepada isu-isu kebangsaan yang harus didiskusikan bersama sehingga ada pencerahan dan jalan keluar. Nilai-nilai luhur Pancasila selalu menjadi penghayatan dan pengalaman dalam setiap laku tindakan baik bermasyakat berbangsa dan bernegara. Jamaah kopdariyah ini mampu mengaktualisasikan nilai-nilai Pancasila dalam setiap kegiatan dan memberikan keteladanan dalam berdiskusi dan praktik kebangsaan. Metode penelitian menggunakan pendekatan deskriptif kualitatif melalui observasi, wawancara, dan dokumentasi. Keabsahan data melalui trianggulasi (sumber dan metode). Analisis data menggunakan model Miles dan Huberman yaitu reduksi data, penyajian data, dan penarikan kesimpulan. Hasil penelitian, penanaman nilai-nilai Pancasila dalam Jamaah Kopdariyah. Pertama, kegaiatan Jamaah Kopdariyah dari tokoh, budayawan, seniman dan para jamaah ini dalam kegiatan selalu menanamkan nilai-nilai yang terkandung dalam Pancasila. Kedua, kegiatan Jamaah Kopdariyah mengamalkan pentingnya nilai-nilai Pancasila dalam mewujudkan kehidupan yang harmoni berdasarkan sila-sila Pancasila.Pilgrims kopdariyah is a community of faith, cross youth and culture.This community always putting on a meeting group about actual current issues in Indonesia, such as; poltic, economic, social, and culture. It is as evidence the pilgrims kopdariyah community notice to nationality current issues that must be discussed to find way out. Enlightenment and values sublime pancasila has always been the feel and experience in every sold is the act of good citizenship. National and state pilgrims kopdariyah was able to actualize values pancasila in any activity and gave an exemplary in discussions and practices national anthem. Research methodology use descriptive qualitative approach through observation, interview, and documentation.The validity of data over and methods trianggulasi. Data analysis model miles and use the data huberman reduction, presentation of data, and withdrawals conclusion.First, research planting pancasila values in pilgrims kopdariyah. First, kegaiatan pilgrims kopdariyah of figures, cultural, artists and those pilgrims in the imparting values this always contained in pancasila. Second, pilgrims had the importance of activities kopdariyah pancasila values in manifesting life based on pancasila sila-sila whose harmony.
Faktor-Faktor Mempengaruhi Terjadinya Perilaku Perundungan(Bullying) pada Siswa SMPN Se-Kecamatan Kediri Lombok Barat
Authors: Haslan Muhammad Mabrur , Sawaludin Sawaludin , Fauzan Ahmad
Published: April 2022

Penelitian ini bertujuan mengidentifikasi faktor-faktor yang mempengaruhi perilaku perundungan (bullying) bagi siswa SMP Negeri Se-Kecamatan Kediri Lombok Barat. Hasil Penelitian sebagai berikut: faktor-faktor yang mempengaruhi perilaku perundungan (bullying) bagi siswa SMP Negeri Se-Kecamatan Kediri Lombok Barat yaitu: faktor keluarga (perceraian orang tua, orang tua yang bekerja di luar negeri), faktor , faktor ekonomi, dan faktor lingkungan sosialThis study aims:  to identify factors influence behavior bullying for yunior high school Kediri Disrtrict West Lombok (3) to identify impact behavior bullying for yunior high school Kediri District West Lombok.The Results of research etc: to identify factors influence behavior bullying for yunior high school Kediri Disrtrict West Lombok, such as: family problem factor (divorce, labor), economic factor, and social invironment
Penyebab Terjadinya Kekerasan Terhadap Anak (Studi Kasus di Kabupaten Sumbawa)
Authors: Kurniawansyah Edy , Dahlan Dahlan
Published: April 2022

Anak merupakan karunia Allah SWT yang harus mendapat perlindungan, bimbingan, dan pembinaan secara konsisten karena didalam dirinya melekat harkat dan martabat sebagai manusia seutuhnya, sehingga ia memiliki hak-hak asasi yang sama seperti hak-hak asasi yang dimiliki oleh individu-individu lainnya. Adapun yang menjadi rumusan masalah dalam penelitian ini adalah apa penyebab terjadinya kekerasan terhadap anak di Kabupaten Sumbawa. Penelitian ini merupakan jenis penelitian kualitatif deskriptif. Teknik pengumpulan data yaitu wawancara, observasi dan dokumentasi. Pengolahan data akan dianalisis dan diolah secara deskriptif kualitatif. Hasil penelitian menunjukan bahwa penyebab terjadinya kekerasan terhadap anak yaitu timbulnya hasrat seksual secara alamiah yang tidak diiringi pengendalian diri, kurangnya pengawasan orang tua terhadap anak, pergaulan bebas, kondisi ekonomi, pengaruh media pornografi dan pengaruh lingkunganChildren are a gift from Allah SWT who must receive protection, guidance, and guidance consistently, because they have inherent dignity as a whole human being, so that they have the same human rights as other individuals. The formulation of the problem in this study is what causes violence against children in Sumbawa Regency. This research is a type of descriptive qualitative research. Data collection techniques are interviews, observation and documentation. Data processing will be analyzed and processed in a qualitative descriptive manner. The results showed that the causes of violence against children were the emergence of natural sexual desires that were not accompanied by self-control, lack of parental supervision of children, promiscuity, economic conditions, the influence of pornographic media and environmental influences.
Оцінка життєвого стану деревних видів рослин природно поширених на девастованих землях залізорудного відвалу
Authors: Савосько Василь Миколайович , Бєлик Юлія Віліївна , Лихолат Юрій Васильович
Published: April 2022

Актуальність досліджень зумовлена важливістю пізнання закономірностей природного поширення деревних видів рослин на девастованих землях залізорудних відвалів Криворіжжя як теоретичної передумови гармонізації екологічного середовища промислових регіонів. Мета досліджень — з позиції екосистемного підходу оцінити сучасний життєвий стан деревних видів рослин, які природно зростають на девастованих землях залізорудного відвалу. Матеріалами роботи слугували результати власних досліджень, які виконували за загальноприйнятими методиками упродовж 2020–2021 рр., на території Петровського відвалу Криворізького залізорудного регіону. Оцінку сучасного життєвого стану виконували за методикою В.А. Алексєєва. В наш час рослинність на Петровському відвалі, який є модельним для регіону, представлена природними угрупованнями, має фрагментарний характер та являє собою рідколісся. Встановлено, що в межах Петровського відвалу природно зростають 32 види деревних та чагарникових рослин (25 родів та 15 родин). Сучасний життєвий стан деревних видів рослин відвалу оцінений як «Ослаблений» (65–71 умовних балів за шкалою В.А. Алексєєва). Такі чисельні значення життєвості деревостану на 21–28% нижчі за контрольні показники (природні угруповання Гурівського лісу). Отримані нами результати свідчать, що екологічні умови девастованих земель Петровського залізорудного відвалу відносно сприятливі для росту та розвитку деревних видів рослин. З’ясовано, що береза повисла (Betula рendula Roth.), клен ясенелистий (Acer negundo L.) та робінія звичайна (Robinia pseudoacacia L.) є достатньо адаптованими до умов місцезростань відвалу. Життєвий стан цих видів оцінено як «Здоровий»: 90–95 умовних балів за шкалою В.А. Алексєєва.
Роль елементів інфраструктури речень публіцистичних текстів в адресації мовлення
Authors: Грицина В. І.
Published: April 2022

Розглянуто найбільш типові форми вираження загальної адресації - іменники у множині, що виступають у ролі звертань, та імперативні форми дієслова, якими виражаються вставні слова. Розкрито форми індивідуальної адресації, що використовуються з метою моделювання ситуації безпосереднього спілкування. індивідуальна адресація виражається найчастіше іменниками однини кличного (рідше називного) відмінка у звертаннях та дієсловами другої особи у вставних конструкціях.
Історія похідних з конфіксом за-...-ник в українській мові
Authors: Іншакова І. О.
Published: April 2022

Проаналізовано історію похідних з кофіксом за-...-ник у двох окремих обстежених текстах староукраїнської мови. Наголошено, що, увійшовши до складу інвентаря дериваційних засобів української мови в XI - ХІІІ ст., конфікс за-...-ник стає в сучасній українській мові високопродуктивною словотвірною морфемою.
National innovation systems and technology transfer of SCO countries
Authors: Solovieva Yuliana
Published: April 2022

The article considers the forms and conditions of interaction between the participants in the innovation process, the specialties of creating and developing the organizational system of technology transfer in the member countries of the Shanghai Cooperation Organization (SCO). Based on the analysis of transfer systems operating in various countries (China, Kazakhstan, Kyrgyzstan, Russia, Tajikistan, Uzbekistan), the authors highlight key and most promising areas for the development of integration of the scientific, educational, industrial spheres and the state in order to form special mechanisms for organizing innovative processes that ensure effective interaction between all its participants. The purpose of the article is to analyze the national innovation systems of SCO member countries, since each of these countries has gone its own way of innovative development, justified by regional characteristics (climatic, cultural, socio-economic, etc.). As basic research methods we used system approach, comparative and statistical analysis of indicative values of innovation and technological development of the SCO member countries.The authors conclude that it is necessary to create an organizational system based on the integration of state institutions, science, business and education in the Shanghai Cooperation Organization member countries in order to form competitive high-tech products, improve the export structure by increasing the share of innovative products in it and reducing the raw materials orientation, and increase the status of countries in the world technology market.
Desain Prototipe Handwell Universal Tool Grinding Machine Menggunakan Konsep Manufaktur Teknologi 3D Printer
Authors: Ratlalan Roberth Marshall
Published: April 2022

Abstract : The presence of the manufacturing world has brought a huge impact on the progress of science and technology in the industry which is currently growing rapidly, especially in the field of industrial automation. Additive Manufacturing known as 3D printing Technology in its philosophy of helping humans in completing every task by playing a very important role in product development, prototyping, and manufacturing process.The results of the manufacturing process using a 3D printer are very good, where the design results can be translated to a 3D Printer and produce objects that match the design results from the software inventor. Success in this manufacturing process is obtained from the results of setting the 3D printer parameters during the proper slicing process, such as setting material temperature, support, printer speed, fan speed, layer thickness (quality), wall thickness (Shell), Infill (filler). and others.Â Keywords: Prototype Design, 3D Printer, Manufacturing Process
The impact of the lung EDRN-CVC on Phase 1, 2, & 3 biomarker validation studies
Authors: Kammer Michael N. , Deppen Stephen A. , Antic Sanja , Jamshedur Rahman S.M. , Eisenberg Rosana , Maldonado Fabien , Aldrich Melinda C. , Sandler Kim L. , Landman Bennett , Massion Pierre P. , Grogan Eric L.
Published: April 2022

The Early Detection Research Network’s (EDRN) purpose is to discover, develop and validate biomarkers and imaging methods to detect early-stage cancers or at-risk individuals. The EDRN is composed of sites that fall into four categories: Biomarker Developmental Laboratories (BDL), Biomarker Reference Laboratories (BRL), Clinical Validation Centers (CVC) and Data Management and Coordinating Centers. Each component has a crucial role to play within the mission of the EDRN. The primary role of the CVCs is to support biomarker developers through validation trials on promising biomarkers discovered by both EDRN and non-EDRN investigators. The second round of funding for the EDRN Lung CVC at Vanderbilt University Medical Center (VUMC) was funded in October 2016 and we intended to accomplish the three missions of the CVCs: To conduct innovative research on the validation of candidate biomarkers for early cancer detection and risk assessment of lung cancer in an observational study; to compare biomarker performance; and to serve as a resource center for collaborative research within the Network and partner with established EDRN BDLs and BRLs, new laboratories and industry partners. This report outlines the impact of the VUMC EDRN Lung CVC and describes the role in promoting and validating biological and imaging biomarkers.
Federated learning: Applications, challenges and future directions
Authors: Bharati Subrato , Mondal M. Rubaiyat Hossain , Podder Prajoy , Prasath V.B. Surya
Published: April 2022

Federated learning (FL) refers to a system in which a central aggregator coordinates the efforts of several clients to solve the issues of machine learning. This setting allows the training data to be dispersed in order to protect the privacy of each device. This paper provides an overview of federated learning systems, with a focus on healthcare. FL is reviewed in terms of its frameworks, architectures and applications. It is shown here that FL solves the preceding issues with a shared global deep learning (DL) model via a central aggregator server. Inspired by the rapid growth of FL research, this paper examines recent developments and provides a comprehensive list of unresolved issues. Several privacy methods including secure multiparty computation, homomorphic encryption, differential privacy and stochastic gradient descent are described in the context of FL. Moreover, a review is provided for different classes of FL such as horizontal and vertical FL and federated transfer learning. FL has applications in wireless communication, service recommendation, intelligent medical diagnosis system and healthcare, which we review in this paper. We also present a comprehensive review of existing FL challenges for example privacy protection, communication cost, systems heterogeneity, unreliable model upload, followed by future research directions.
Emotional AI: Legal and ethical challenges1
Authors: Gremsl Thomas , Hödl Elisabeth
Published: April 2022

The European Commission has presented a draft for an Artificial Intelligence Act (AIA). This article deals with legal and ethical questions of the datafication of human emotions. In particular, it raises the question of how emotions are to be legally classified. In particular, the concept of “emotion recognition systems” in the sense of the draft Artificial Intelligence Act (AIA) published by the European Commission is addressed. As it turns out, the fundamental right to freedom of thought as well as the question of the common good and human dignity become relevant in this context, especially when such systems are combined with others, such as scoring models.
Mild Traumatic Brain Injury Is Related to Elevated Cerebrospinal Fluid Tau in Alzheimer’s Disease Dementia
Authors: LoBue Christian ,   for the Alzheimer’s Disease Neuroimaging Initiative, Kelley Brendan J. , Hart John , Helphrey Jessica , Schaffert Jeff , Cullum C. Munro , Peters Matthew E. , Douglas Peter M.
Published: April 2022

Few studies have examined an association between mild traumatic brain injury (mTBI) and Alzheimer’s disease (AD). For this reason, we compared an AD dementia group with an mTBI history (n = 10) to a matched AD control group (n = 20) on measures of cognitive function, cerebral glucose metabolism, and markers of amyloid and tau deposition. Only a trend and medium-to-large effect size for higher phosphorylated and total tau was identified for the mTBI group. A history of mTBI may be associated with greater tau in AD, indicating a potential pathway for increasing risk for AD, though further evaluation with larger samples is needed.
Making the Case for the Accelerated Withdrawal of Aducanumab
Authors: Whitehouse Peter J. , Saini Vikas
Published: April 2022

U.S. Food and Drug Administration–s (FDA) approval of aducanumab (Aduhelm® in the US) as a treatment for mild cognitive impairment of the Alzheimer type and Alzheimer–s disease has raised such major concerns about efficacy, safety, FDA processes, and regulatory capture that Biogen–s license to market this biologic should be immediately withdrawn. Aducanumab has not demonstrated benefit to patients, failed to meet regulatory guidelines, and is likely to cause both individual and societal harm.
3D-CNN frameworks for mesial temporal lobe epilepsy diagnosis in MRI images
Authors: Ruowei Qu , Shifen Wang , Zhengfang Liu , Junhua Gu , Guizhi Xu
Published: April 2022

Epilepsy is one of the most serious neurological diseases in the world. The mesial temporal lobe epilepsy (MTLE), especially hippocampal sclerosis (HS) is the most common pathological causes of epilepsy. With the development of computer visualization technology, there are many auxiliary diagnostic approaches based on deep learning algorithms. However, the traditional 2D-CNN framework can only accept single layer inputs. In such case, the associations between the brain planes are ignored, which may lead to misdiagnosis or missed diagnosis. 3D-CNN framework can accept cubes as the input of the neural network, so that network parameters will carry more structural and logical information of the brain in the spatial domain. Therefore, this study designed a 3D-CNN framework for MTLE diagnosis in T2-FLAIR MRI images. We retrospectively collected 15 patients with the MTLE and 15 age-matched controls who underwent T2-FLAIR studies. Then, we proposed three 3D-CNN based on ResNet to identify symmetrical differences in the corresponding areas of the brain in both sides. The symmetrical cubes were combined as the inputs for the 3D-CNN framework. Performances of the proposed framework were compared with radiomics algorithms and visual assessment. The proposed 3D-CNN based on ResNet-34 performs the best among all the algorithms. Moreover, due to the non-inferiority testing for paired data, the proposed 3D-CNN frameworks based on the ResNet were not inferior to that of visual assessment which was unblinded to the clinical information. The proposed 3D-CNN framework could diagnosis MTLE in MRI images accurately and efficiently, which might be applied as a computer-assisted approach for the future diagnosis of epilepsy patients.
Energy consumption in cluster communication using mcsbch approach in WSN
Authors: Ravindran Vijay , Vennila C.
Published: April 2022

Internet of Things (IoT) proposed a new digital computing paradigm enabling interaction between devices and machines. It deliberately creates connectivity between the internet, electronics, and other forms of hardware. A novel modern cluster supervisor-based cluster head selection algorithm (MCSBCH) is proposed for the Wireless Sensor Network (WSN). The proposed cluster supervisor mechanism is responsible for controlling and monitoring the network effectively. In this approach, the cluster supervisor is the heart of the network, and the whole mechanism work under its supervision. The Cluster supervisor (CS) monitors the node’s energy level and allocates CH (cluster head) node. Each node’s energy level is considered for electing the CH. Obviously when the cluster head energy level gets drained, then it allocates the next higher energy node as cluster head. The assigned CH is the next node with the highest energy level known as the backup node. This cluster supervisor (CS) is supported by the cluster head (CH) and other backup nodes in the network. The proposed MCSBCH is boosted with an enhanced clustering routing protocol. An experimental result is based on the aspect of a lifetime, energy consumption, and throughput, to test the proposed mechanism performance.
RETRACTED: Scalable tensor factorization for recovering multiday missing intramuscular electromyography data
Authors: Akmal Muhammad , Zubair Syed , Jochumsen Mads , Zia ur rehman Muhammad , Nlandu Kamavuako Ernest , Irfan Abid Muhammad , Niazi Imran Khan
Published: April 2022

This article has been retracted. A retraction notice can be found at https://doi.org/10.3233/JIFS-219433.
RETRACTED: EBSRMF: Ensemble based similarity-regularized matrix factorization to predict anticancer drug responses
Authors: Shahzad Muhammad , Tahir M. Atif , Khan M. Atta , Jiang Richard , Malick Rauf Ahmed Shams
Published: April 2022

This article has been retracted. A retraction notice can be found at https://doi.org/10.3233/JIFS-219433.