bluuebunny/crossref_metadata_2025 huggingface dataset:
O etyce pracy nauczyciela akademickiego
Authors: Polańska Aurelia
Published: February 2023

In all the volumes of Annales. Ethics in Economy there are several interesting papers about
the ethics of teaching in academic schools. I would like to add my paper to this collection
at the conference in 2007.
In my paper I write about my own experiences during the work with students in several schools.
In this description I use the method of job analysis recommended by the International Labour
Organization in Geneva: the praxeological method of prof. Kotarbiński and an encyclical of
John Paul II.
I attempt to prove the thesis that teaching of ethics to students makes sense and gives results only
when the teacher is able to convince young people to the value of honest work in their personal lives.
This thesis may be promoted by positively motivated teachers and well organized working processes in
the school.
Dylematy i konflikty moralne polityków i lekarzy w ustanawianiu zadań systemu opieki zdrowotnej
Authors: Gałuszka Mieczysław
Published: February 2023

Medicine is the field of knowledge and set of clinical practices, characterized by the presence of
politics and ethics on all the levels. Politics should be treated as a domain of power, which aims to make
strategic decisions concerning health of the citizens leading to form socially accepted objectives of
health care policy. Ethics sets axiological frames for morally just decisions both political and medical
in the field of health care.
The article analyzes the reasons of conflicts and moral dilemmas in the health care system.
Decisions which are made within health care system should accomplish five criteria: medical,
economical, social, legal and axiological. The term “moral panic” is used to illustrate situations
concerning corruption and moral atrophy of doctors.
Etyka w bankowości – dylematy pracownika bankowego
Authors: Lipiński Czesław
Published: February 2023

Credibility and reliability of counter-partners are the most important features required for
the efficient functioning of financial markets. Violating these requirements is an important aspect of
the operational risk, posed by the human factor – both internal (managers, employees) and external
(customers, shareholders, competitors, supervisors). Therefore, having a limited impact on
the behaviour of outside persons, the financial institutions formulate high standards towards their own
personnel. It concerns formal qualifications and professional experience, as well as specific personality
traits and appropriate behaviour in various situations.
These standards are specified in numerous recent ethics codes – documents formulating the socalled
‘corporate governance best practices’ in internal and external relations to other people. The aim
of this paper is to draw attention to the fact that some of these standards generate in praxis a number of
dilemmas or even conflict situations, when there appears a question of to what extent the application of
a given rule does not breach other rules. Theoretically, corporate governance practices should be
internally consistent. However, everyday experience brings such a multitude of real situations, diverse
human characters or individual reactions that there appears a need for a sensible compromise between
values of equal importance which, in some cases, prove contradicting.
Problematyka wymogów etycznych dotyczących osoby notariusza i sporządzanych przez niego czynności
Authors: Stawecki Marek
Published: February 2023

The fundamental rules which should be followed by Notary Public are: honesty, reliability,
detachment and impartiality, as well as keeping the professional secret.
As a crucial participant in creating and carrying into effect legal structures of free market, Notary
Public performs public functions. Therefore, he or she is authorized to give an official character to
declarations of persons being their clients. In view of the foregoing, the notary should secure such
documents in trading abiding by the rules and regulations of the governing law and ethics.
With a view to a special role of the profession in question in economic trade, The National Notary
Board passed a Notary Public Code of Professional Ethics, by virtue whereof a Notary shall with their
attitude and actions give a good character to their profession and mind its dignity and honor. Any
breach of the above – mentioned rules results in the Notary’s liability.
Notary Public, as a person whose functions play a crucial role in legal trade and who is trusted by
the parties, is responsible for correctness and precision of their activities. Their liability as clients’
confidant may result in civil, legal, disciplinary and tax liability.
Etyka w pracy audytora wewnętrznego
Authors: Krawczyk Marzena , Sekuła Piotr
Published: February 2023

Internal audit provides an independent and objective opinion to the Board
on risk management,
control and governance, by measuring and evaluating their effectiveness in achieving an organisation’s
agreed objectives. It also provides an independent and objective consultancy service to help line
management improve the organisation’s processes.
Internal auditors should respect in their work some ethical rules, especially these included in
the Code of Ethics formed by the IIA. This code is intended to clarify the standard of conduct expected
from all members of the internal audit unit. The main four principles that should be observed are
as follows: integrity, objectivity, competency and confidentiality
Being ethical in internal audit is necessary in order to win the trust of the environment in which
auditors work. However, declaring one’s readiness to respect the Code of Ethics is not enough. Much
more important is to implement and comply with given rules in carrying out audit duties.
Fundacje, media, etyka. Ciąg dalszy rozważań
Authors: Rotengruber Przemysław
Published: February 2023

The object of my last year’s presentation were communication (ethical, integration, political)
threats posed by a foundation seen as an extension to a company in its traditional sense. I came to
the conclusion that an automatic transfer of social trust capital to the parent company (in certain,
specified by me, contexts) causes the foundation to betray its mission. It is the company that becomes
the main beneficiary of mutual aid activities.
This year, the paper addresses the following three issues. Firstly, I intend to show the symbolic
pressure exerted on both consumers and producers, which is made possible by the ‘labeling’ of products
of ‘socially sensitive’ companies. There would be no point questioning the fact of shaping social
attitudes if it weren’t for an ambiguous position of the co-ordinator of the enterprise, who becomes vested
with the rights of a certification authority.
Another question under consideration is the transformation of a foundation into a quasi-company.
A third-sector organization adds business activity to the goals specified in its by-laws. It results
in taking on highly-skilled professionals who have nothing to do with charitable activity of a third
sector organization.
Finally, there is a danger of a foundation’s approximation to a second-sector organization.
A foundation may be financed by a public administration body. This may lead to the division of
the final product of a foundation between the beneficiaries and the body which sponsors its operation
using a ‘lump sum’ payment.
Whichever the problem, the key aspect seems societal control over mutual aid activities. Its lack
results in an abuse of power and the diminished trust of the manipulated society in effective cooperation.
Stosunek do przeciwników politycznych w kampaniach wyborczych – próba oceny etycznej
Authors: Walerjan Bożena
Published: February 2023

The election campaigns in Poland have become oriented to the still more extent on fighting back
the political opponents. Only seldom we can watch skirmishes about programmes and battles with
the use of substantial arguments. Instead, we observe more and more mutual accusations, personal
reproaches and attempts of slandering the opponent using unethical methods. The attitude of one
politician to another assumed quite special features both on the level of verbal behaviour and their
attitudes. Almost in every election campaign since the year 1989 the voters have had the occasions
to observe the behaviours of politicians which were far from the moral standards and which
significantly lowered the level of political culture in Poland. Since a few years rival discreditations,
intrigues, announcing untrue information about opponents and creation of media facts have dominated
during the election battles. Occurrences of such type are crucial for political alienation among
the citizens and contribute to preservation of a negative picture of the politics itself as a sort of
dishonest and immoral activity. Various methods of depreciation of opponents are still more and more
willingly used. This paper will discuss selected behaviours of political competitors towards each other;
also an attempt will be undertaken to assess those behaviours from the ethics’ point of view.
Constraints Perceived by the Kennel Owners in Rearing of Indigenous Dog Breeds (Rajapalayam, Kanni and Chippiparai Dog) in Southern Districts of Tamil Nadu
Authors: Selvakkumar R.
Published: February 2023

The increased demand for indigenous native dog’s breeds like Rajapalayam, Kanni and Chippiparai, leading to flourishing of more kennels in and around the breeding tract of the above breeds. The breeders without an experience in dog breeding are also involved in this dog breeding business and some of them face number of problems in running the business and meet with fiscal loss. Individuals who run the kennel with successful managemental practices and marketing tactics can only survive in this business. Considering the above problems in mind, a study was carried out to list out the major constraints perceived by the kennel owners of the indigenous dog breeds so as to sketch out a package of practices in indigenous dog breeding business. A study was carried out to identify the major constraints perceived by the dog breeders of the above indigenous dog breeds. The data were collected by pre-tested interview scheme from 39 kennel owners randomly selected from the breeding tract viz Virudhunagar, Tirunelveli and Thoothukudi districts of Tamil Nadu. Prime constraints listed in the previous study were used to get response form the kennel owners. Kennel owners with more than five year of experience and maintaining more than 25 adult breedable dogs were interviewed. The constraints perceived by the kennel owners were collected and Garett’s ranking technique was followed to rank the constraints perceived by them in their business. The study revealed that, majority of the dog breeders reported that, the unavailability of timely veterinary care (83.80%) is the major problem in dog breeding business followed by high cost involved in establishment of kennel (70.15%), difficulty in getting KCI registration for their dog (58.23%), unavailability of Vaccine (56%), frequent disease problems (50%), unethical business tactics by the competitors (48.33), inbreeding and inherited diseases (45%), pup Mortality(40%), poor breeding performance of dogs (35%), low demand and low price for the pups (28%) and unaware about scientific management (17%).
Reflections: Prerequisites for quality learning in the 21st century
Authors: Jurs Pavels , Špehte Elita , Samusevica Alida , Kulberga Inta , Titrek Osman
Published: February 2023

Today's society requires competitive professionals who can respond operationally to ever-changing life situations, think creatively, focus their activities on achieving the goals set and this is why the new challenge of the 21st century education is to balance vocational and general education objectives to meet changing societal needs. One aspect that arises directly from the quality of education is reflection. The aim of this study is to find the implementation of learning reflection by teachers and how the influence of the use of reflection in the learning process. Depending on the results of this research, it will be clear whether the teachers will use reflection as teaching and learning method in their lessons at school. This research used quantitative  method to determine the effect of reflection.  The type of research is quantitative research using an online survey method. The results of survey certifies that 64% of teachers agree that reflection helps the students to sort out their thinking process and allows them to improve on their own and 72% of teachers answered that they would like to continue to use reflection activities at their lessons because students’ curiosity can motivate them to engage in the learning process.
Keywords: Learning, quality learning, reflection, schools, students, teachers
Students' entrepreneurial attitudes: Does the integrated Learning model based on tri dharma in entrepreneurship education work?
Authors: Amalia Nafiati Dewi , Sukirno Sukirno , Mulyani Endang
Published: February 2023

The role of entrepreneurship education is urgently needed due to the lack of entrepreneurial activities, the curriculum not being standardized, the lack of skills of the lecturers in entrepreneurship, and less collaboration among the practitioners, education institutions, and students. Therefore Entrepreneurship education has not been planned and integrated well into higher education's functions to develop student entrepreneurial attitudes. This research aims to analyze the effectiveness of the integrated entrepreneurship education model of tri dharma education in developing student entrepreneurial attitudes in higher educations. Indicators of student entrepreneurial attitudes were measured by aspects of student leadership, student personality, and student personal assessment and the research analysis through paired sample t-test The result indicates that the integrated entrepreneurship education model of tri dharma education was effective and can be used as an alternative learning model to improve student entrepreneurial attitudes. It can be helpful in the students to increase their entrepreneurship attitudes after school in the community. The researcher recommends further research to compare the tri dharma of entrepreneurship education model with the other model. It also recommends cooperatively formulating and implementing a fit integrative entrepreneurship education program to develop better students' entrepreneurship attitudes in Indonesia.
Keywords: entrepreneurial attitude, entrepreneurship education, Tri Dharma education, integrated education,  learning models
Brilliant Blue Chromatic Traps Plus Commercial Attractors are Effective Capturing Adults Frankliniella Occidentalis (Thysanoptera: Thripidae) in Blackberry Crops
Authors: Esteban Samuel Cruz
Published: February 2023

Western flower thrips (WFT) are a major insect pest of blackberry (Rubus ulmifolius, Rosaceae) crops in Mexico, causing significant damage to blackberry crops. Yellow and blue traps are used to monitor adult thrips populations during the blossom season. However, the effect of different shades of these colours on the capture of Frankliniella occidentalis Pergande (Thysanoptera: Thripidae) is not clearly known. The current study evaluated four shades of yellow (opaque, neutral, brilliant, and phosphorescent) and three shades of blue (opaque, neutral, and brilliant), subsequently, the most attractive shade (brilliant blue or high lustre blue was selected, and different geometric figures (circle, half-circle, rhombus, triangle, inverted triangle, and square) were evaluated on a black background in blackberry crops. Brilliant blue and phosphorescent yellow traps captured the highest number of WFT adults; but brilliant blue traps captured numerically more WFT adults than phosphorescent yellow traps. The use of different geometric figures of brilliant blue on a green background did not improve thrip capture compared to the brilliant blue trap without a background. The kairomone Lurem-TR increased the number WTF adults captured 2 - 3 times more the unbaited trap, and 2 mg of eugenol increased 1.5 - 2.5. These results are useful to complement the monitoring system for F. occidentalis in host crops of this pest.
Real options analysis applied to investment projects in planted forests of Pinus
Authors: SIMÕES Danilo , ROCHA Qüinny Soares , MUNIS Rafalele Almeida , Da SILVA Richardson Barbosa Gomes , GARCIA Giovani Caprioli
Published: February 2023

Planted forests are long-term projects involving a large monetary contribution, and generally require the incorporation of managerial flexibility. As the traditional methodology for economic evaluation does not allow for the incorporation of these flexibilities, our study aimed to analyze whether investment projects in planted forests of Pinus elliottii Engelm. are economically feasible, by applying a real options analysis. We used empirical data from one hectare of a planted forest of P. elliottii with a 14-year planning horizon. Managerial flexibilities were incorporated in combinations and also separately, as options to defer, expand or abandon the investment project. Through Monte Carlo simulation, the present value of USD 1.016 was conditioned to anticipated return values from the second to the fourteenth year, with a volatility return of 14.5%. With real options analysis, the value of the combined options was USD 29, which, in terms of traditional net present value, showed an expanded net present value of USD 468. The real options analysis thus shows that investment projects in planted forests of P. elliottii are economically feasible. Given that real options analysis is a methodology not widely used in the forestry sector for economic analysis of investment projects, this study can be used to assist forest managers in analysing investment risks and decisions, specifically those related to market fluctuations of planted forests of Pinus spp., assuming that the real options of deferral, expansion and abandonment of an investment project are used.
Sag mir, wo du wohnst, und ich sage dir, wen du wählst? : Potenziale und Grenzen des datengestützten Tür-zu-Tür-Wahlkampfs in Deutschland
Authors: Koprivnjak Oliver
Published: February 2023

Das Buch verfolgt zwei Haupt-Ziele: Auf der theoretischen Ebene soll ein system- und akteurstheoretischer Ansatz vorgestellt werden, mit dem re-konstruiert wird, aus welchen Gründen sich die Wahlkampfkommunika-tion von Parteien in Form eines Anpassungshandelns datengestützten Strategien zuwendet. Auf der empirischen Ebene soll am Beispiel des datengestützten Tür-zu-Tür-Wahlkampfs aufgezeigt werden, wie sich ein solches Anpassungshandeln der Parteien unter den spezifischen Kontextbedingungen Deutschlands in der Wahlkampf-Praxis manifestiert. Konkret soll dabei die Forschungsfrage untersucht werden, inwie-fern der datengestützte TzT-Wahlkampf von deutschen Parteien strate-gisch organisiert wird. Methodisch wird die Studie dazu auf qualitative Befragungen mit Wahlkampf-Mitarbeitenden der großen deutschen Parteien zurückgreifen.
Economic Analysis of Migrants and Natives on the German Labor Market : Microeconometric Evidence from German Administrative Data
Authors:   , Jost Oskar
Published: February 2023

The following dissertation contains four empirical articles discussing different aspects of unemployment and wages considering differences between migrants and natives in especial. The first article analyses wage differentials between migrants and natives on the German labor market. The second article of this dissertation extend the conventional wage curve by considering occupational unemployment levels. Article 3 and 4 focus on the long-term scarring effect of unemployment and recalls in Germany, respectively. Die vorliegende Dissertation enthält vier empirische Artikel, die sich mit verschiedenen Aspekten der Arbeitslosigkeit und Lohnstruktur zwischen Migranten und Einheimischen auseinandersetzen. Der erste Artikel analysiert das Lohngefälle zwischen Migranten und Einheimischen auf dem deutschen Arbeitsmarkt. Der zweite Artikel erweitert die konventionelle Lohnkurve indem berufliche Arbeitslosigkeit berücksichtigt wird. Artikel drei und vier konzentrieren sich auf die langfristigen Folgen der Arbeitslosigkeit sowie Wiedereinstellungen (Recall) in Deutschland.
Video Tutorial Tata Rias Pegantin Lintau Buo Tanah Datar Sumatera Barat
Authors: Hanifi Zil Afi Nasril  , Hanifi Zil Afi Nasril  , Sri Irtawidjajanti
Published: February 2023

HANIFI ZIL AFI NASRIL, Video Tutorial Tata Rias Pengantin Lintau Buo Tanah Datar Sumatera Barat, Tugas Akhir : Jakarta Program Studi Diploma 3 Tata Rias, Jurusan Tata Rias, FakultasTeknik, Universitas Negeri Jakarta, 2022.

Lintau Buo adalah kecamatan di kabupaten Tanah Datar, Sumatera Barat. Daerah Lintau Buo memiliki karakteristik pada tata rias pengantinnya. Tata rias pengantin Lintau Buo Tanah Datar terdiri dari tata rias wajah, tata rias rambut atau hijab, tata busana dan aksesoris. Penilitian pada tugas akhir ini menggunakan metode Research and Development (R&D) yang akan menghasilkan produk yang telah teruji kefektifannya. Memperkenalkan tata rias pengantin Lintau Buo Tanah Datar Sumatera Barat kepada masayarakat luas, baik masyarakat Sumatera Barat maupun masyarakat diluar Sumatera Barat yang dikemas menjadi video tutorial. Dalam pembuatan video tutorial tersebut sudah melalui proses pra produksi, produksi, pasca produksi, penelitian, pengolahan data dan hasil penelitian. Video tutorial tersebut telah di uji kelayakannya dan sudah memenuhi kriteria validasi yang di dapat dari para ahli menggunakan skala likert. Ahli tata rias pengantin memberi nilai dengan persentase 98%  ahli media memberi nilai dengan persentase 100% dan ahli materi memberi nilai dengan persentase 82% . Dapat disimpulkan bahwa video tutorial tersebut Sangat Baik dan Layak untuk dijadikan media pembelajaran mengenai tata rias pengantin Lintau Buo Tanah Datar Sumatera Barat.
Анализ динамики эпидемического процесса COVID-19 в мире за неделю с 28.01.2023 г. по 03.02.2023 г.
Authors: Зимирова Анастасия , Поспелов Михаил , Иванова Александра , Дмитриева Людмила , Чумачкова Елена , Карнаухов Игорь , Щербакова Светлана , Кутырев Владимир
Published: February 2023

В обзоре представлен анализ эпидемиологической ситуации в странах мира по COVID-19 за неделю с 28.01.2023 г. по 03.02.2023 г.
Effectiveness of Public–Private Efforts to Conserve Tricolored Blackbird Colonies on Agricultural Lands in the San Joaquin Valley, California
Authors: Castañeda Xerónimo , Clipperton Neil , Airola Daniel A. , Arthur Samantha , Sousa Paul
Published: February 2023

Since the early 1990s when much of the population of the Tricolored Blackbird (Agelaius tricolor) began nesting in fields of triticale grown for dairy silage in the San Joaquin Valley, many colonies have been destroyed inadvertently during harvest. After previous inconsistent efforts, in 2015 a Regional Conservation Partnership Program brought the dairy industry, Natural Resource Conservation Service, Audubon California, California Department of Fish and Wildlife, and other partners together in an effort to stem the losses. The program located colonies and compensated farmers for crop value lost when the harvest was delayed until after the blackbirds fledged and encouraged creation of alternative nesting habitat to attract nesting birds away from agricultural fields. Before 2015, data on the numbers of colonies in silage fields, and on the blackbirds’ productivity conserved and lost, are complete only for 2005–2009, when only 43% of colonies encompassing 60% of the monitored nestings avoided destruction. From 2015 to 2022, 93% of colonies representing 96% of nesting attempts were conserved, and the number of birds nesting in silage increased by as much as 100,000. The program’s success resulted from the adequacy of federal funding, protection provided by the species’ listing as endangered by the state of California, and effective communications and cooperation among the partners and within the dairy industry. Protection of colonies in silage fields since 2015 likely contributed to the substantial increase in the numbers of birds nesting in this habitat and perhaps to an increase in California’s Tricolored Blackbird population as a whole. Continued effort is needed to achieve the species’ recovery.
Foraging Habitat and Its Effects on the Tricolored Blackbird’s Breeding Distribution and Abundance in the Sierra Nevada Foothills, California
Authors: Airola Daniel A. , Collins Tara L. , McColl Christopher J. , Lozano Michael R. , Furnas Brett J. , Krolick David E.
Published: February 2023

The grassland-dominated eastern Central Valley and Sierra Nevada foothills of California, from Placer to Stanislaus counties, supported at least 43,000–55,000 breeding Tricolored Blackbirds (Agelaius tricolor) annually from 2014 to 2018—about 30% of the statewide population. We found that within 5 km of a colony, the extent of land cover used for foraging, grassland–herbaceous, and to a lesser extent annual crops and irrigated pasture, exceeded their proportions in this region as a whole, suggesting that nesting Tricolored Blackbirds select colony sites where these habitats are more abundant. Other land-cover types were underutilized for foraging, suggesting avoidance. The probability of Tricolored Blackbird occupancy of blocks of 100 km2 was strongly associated with the extent of the selected land-cover types. The relationship between average density of the breeding population and the extent of the selected land-cover types was significant but weaker, implying that other factors are important in determining density. From 2014 to 2018, development and mining eliminated or degraded 9 of 79 colony sites and made 4 others unsuitable by reducing the extent of nearby foraging habitat, although the total breeding population in the region did not decline. We recommend that conservation measures for the Tricolored Blackbird in federally and state-approved habitat-conservation plans in Placer and Sacramento counties, which support the largest breeding populations in the central Sierra foothills but where urban development is rapid, be reevaluated on the basis of recent colony locations and recognition of the critical role of grassland, annual crops, and irrigated pasture as foraging habitat.
The Northernmost Record of the Least Grebe (Tachybaptus dominicus bangsi) in Baja California
Authors: Ruiz-Campos Gorgonio , de León-Girón Gonzalo , Gaona-Melo Tonatiuh , Marrón Gerardo , Unitt Philip , Hargrove Lori
Published: February 2023

A specimen of the Least Grebe (Tachybaptus dominicus bangsi) from San Francisco de la Sierra, Baja Calfornia Sur, Mexico, collected 6 April 2022, was 36 km north of the oasis of San Ignacio, where the species breeds and site of the previous northernmost records on the peninsula. The bird’s occurrence on a small isolated pond yet coming into breeding condition highlight the species’ opportunism, possibly critical to its survival on the arid Baja California peninsula where freshwater oases suitable for the Least Grebe are few.
Meta-analysis of the efficacy and toxicity of paclitaxel combined with platinum (PTX) and fluorouracil combined with cisplatin (PF) in the treatment of concurrent chemoradiotherapy (CCRT) for unresectable esophageal cancer
Authors: Wang Lan , Zhang Xiaolin , Chen Xiaoxi , Wang Qi , Liu Lihong , Liu Shutang , Han Chun
Published: February 2023

Purpose
To systematically evaluate the efficacy and toxicity of paclitaxel/docetaxel combined with platinum (PTX) and fluorouracil combined with cisplatin (PF) in concurrent chemoradiotherapy (CCRT) treatment of unresectable esophageal cancer.
Methods
PubMed, the CNKI database, and Google Scholar were searched by combining subject words and free words through December 31, 2020; quality evaluation and data extraction of the studies that met the inclusion criteria were carried out independently. Stata 11.1 software was used for the meta-analysis comparing the efficacy and treatment-related toxicity of the two regimens.
Result
After screening, a total of 10 studies were included: four were cohort studies, and six were randomized controlled studies (RCT). A total of 1,098 cases were enrolled comprising 1,047 cases (95.4%) of squamous cell carcinoma and 51 cases (4.6%) of adenocarcinoma; 560 cases (51.0%) in the PTX group and 538 cases (49.0%) in the PF group. There was no significant difference in hematological toxicity, gastrointestinal reaction, or radiation pneumonia between the two groups (P = 0.353, 0.741, and 0.321). Radiation esophagitis from the PF regimen was the most serious (P = 0.002). In terms of short-term efficacy, the CR rate of the PTX group was higher than that of PF group (P = 0.029). There was no significant difference in PR rate, ORR rate, or DCR(Disease Control Rate) rate between the two groups (P = 0.599, 0.057, and 0.164). In terms of overall survival rate, the 1-, 2- and 3-year survival rates of the PTX group were higher than those of PF group (P = 0.048, 0.029, and 0.001). There was no significant difference in the 5-year survival rate between the two regimens (P = 0.076). PFS of the PTX group at 1, 2, and 3 years was higher than that of PF group (P = 0.023, < 0.001, and 0.014).
Conclusions
Compared with the PF regimen, the PTX regimen combined with radiotherapy in the CCRT treatment of unresectable esophageal cancer exhibited benefits in clinical CR rate, OS rate, and PFS rate. There was no difference in hematological toxicity, gastrointestinal reaction, or acute radiation pneumonia between the two regimens. The PTX regimen had lower esophageal toxicity and therefore might be the preferred concurrent chemotherapy regimen for esophageal squamous cell carcinoma.
The Value of 3D arterial spin labeling in early diagnosis and short-term prognostic grouping of Full-Term neonatal hypoxic-ischemic encephalopathy
Authors: liu chang , Ji Hai-Xia , Tian Yang-Hua , Hou Wei-Shu , Ying Da-Wei , Deng Ke-Xue
Published: February 2023

Purpose
To investigate the value of 3D arterial spin labeling(ASL) perfusion imaging and DWI for the early diagnosis of hypoxic-ischemic encephalopathy(HIE) in term neonates and the predictive value of 3D ASL for patient prognosis.
Methods
A total of 60 full-term neonates clinically diagnosed with HIE in our hospital from January 2018 to October 2021 and 60 control group was selected. All HIE neonates were divided into favourable outcome and adverse outcome groups according to their prognosis,and all subjects underwent 3D ASL and DWI simultaneously to compare cerebral blood flow (CBF) and apparent diffusion coefficient (ADC) in each region of interest and analyze the agreement.The areas of interest included bilateral basal ganglia, thalamus, and frontal white matter, and the final average was bilaterally taken.To investigate the correlation between CBF value of HIE in neonates and neonatal behavioral neurological assessment (NBNA), the relationship between early changes of CBF value and prognosis of neonates with HIE。
Results
The CBF values of basal ganglia and thalamus in the adverse outcome group were higher than those in the favourable outcome group, and the difference was statistically significant (P < 0.01); the CBF value of frontal white matter in the adverse outcome group and the favourable outcome group were statistically significant (P < 0.01); the CBF values in the basal ganglia and thalamus of neonates in the HIE group were greater than those of normal controls, and the differences were statistically significant (P < 0.01); the CBF values in the frontal white matter area of neonates in the HIE group were smaller than those in the normal control group, and the differences were statistically significant (P < 0.01). The area under the ROC curve for CBF value was 0.973, the specificity and sensitivity of CBF values were 97.5% and 90.2%;the ADC values of area under the ROC curve was 0.881, and the sensitivity and specificity were 82.5% and 92.7%.respectively CBF values in the basal ganglia region were highly correlated with NBNA scores (r=-0.8196,p < 0.01) and negatively correlated; thalamic CBF values were highly correlated with NBNA scores (r=-0.8504,p < 0.01) and negatively correlated; frontal CBF values were not correlated with NBNA scores (r=-0.0802,p = 0.62).
Conclusion
ASL findings within 1 day after birth in full-term neonates were highly correlated with NBNA scores. It can diagnose HIE early and predict the outcome of functional brain damage with better diagnostic efficacy than DWI.
Fecal carriage and molecular epidemiology of carbapenem-resistant Enterobacteriaceae isolated from children in Henan Province, China
Authors: Yu Jing , Pan Sijia , Tai Shuhong , Zhang Chengwen , Yuan Enwu , Duan Yitao
Published: February 2023

Background: This study sought to investigate the carrier rate of intestinal carbapenem-resistant Enterobacteriaceae (CRE) in children, in Henan Province.
Methods: In a prospective study, 1019 non-repetitive fecal samples were consecutively obtained from outpatient (n = 710) and inpatient children (n = 309). Isolates were cultured in MacConkey medium from fecal specimens, and matrix-assisted laser desorption ionization-time of flight mass spectrometry was used for strain identification. Imipenem and meropenem E-test strips were used for CRE screening, and antimicrobial susceptibility was determined using VITEK-2 AST GN335. Resistance genes and multilocus sequence types were identified by whole-genome sequencing.
Results: The overall CRE colonization rates in children were 1.5%. Five CRE were isolated from outpatient children with a colonization rate of 0.7%. Strains were mainly NDM-5 producing Escherichia coli, which belonged to ST410, ST1193, and ST10885. Ten CRE were isolated from hospitalized children with a colonization rate of 3.2%, mainly NDM-producing K. pneumoniae and NDM-5-producing E. coli. The NDM-producing K. pneumoniae belonged to subtypes, including ST70, ST357, ST491, and ST2864. The blaNDM-5 gene was the major carbapenemase gene harbored by gastrointestinal CRE strains, followed by blaKPC-2. Furthermore, extended-spectrum b-lactamase genes (blaCTX-M, blaTEM, and blaSHV) and AmpC genes (blaDHA-1 and blaCMY-2) were detected. All CRE strains showed high resistance to most of the routinely used antibiotics, except for polymyxin B and tigecycline.
Conclusions: The intestinal CRE colonization rate of children in Henan is very low, and the production of blaNDM carbapenemase was the main mechanism of carbapenem resistance. Different from the main epidemic types of clinically isolated CRE strains, the types of CRE colonizing isolates show diversity.
Comparison of chloroplast genomes of Calypsoinae species (Orchidaceae) living on different lifeforms
Authors: Chen Xiaoyuan , Xiang Xiaoguo , Liu Xuedie , Li Weiyi , Wu Xinchen , Zhou Yadong , Yang Boyun , Luo Huolin
Published: February 2023

Background
The vast majority of angiosperms obtain carbon sources through photosynthesis, while a few Mycoeterotropic plants rely entirely on symbiotic fungi to provide nutrition. The origin and evolution of Mycoeterotropic plant has always been the focus of botanists. Calypsoinae, a common subfamily of Epidendroideae within Orchidaceae, possesses abundant variation in morphology and living habits. Such variation includes that between autotrophy and heterotrophy, a notable discernment that may be exploited to investigate the chloroplast genome evolution of different trophic types of orchids. In this study, the complete chloroplast genome of Danxiaorchis yangii, a heterotrophic orchid, was newly sequenced using illumina HiSeq X ten platform followed by de novo assembly. Moreover, we conducted comparative analysis on 25 Calypsoinae species’ complete chloroplast (CP) genomes, providing insight to explore the chloroplast genome evolution of non-autotrophic plants.
Results
The Danxiaorchis yangii CP genome size is 95,156 bp in length encoding a total of 79 different genes. The CP genomes of 25 Calypsoinae species are typically 88–160 kb in length, while that of the genus Danxiaorchis was typically less than 100 kb, which is consistent with the significantly smaller LSC region of the genus Danxiaorchis. In terms of genome loss, both autotrophic and heterotrophic groups have gene loss phenomena, mainly ndh family loss. Heterotrophic orchid gene loss is more serious, wherein most of the genes associated with photosynthesis have different degrees of deletion. The chloroplast genome of autotrophic orchids was completely collinear without rearrangement or inversion, contrasted with heterotrophic Danxiaorchis, which showed rearrangement and inversion.
Conclusion
This study reported the chloroplast genome sequence of D. yangii, and interpreted its structure and gene number of the chloroplast genome. In addition, by comparing the chloroplast genomes of autotrophic orchids and heterotrophic orchids in Calypsoinae, we found an interesting correlation between the nutrition mode and the chloroplast genome structure. The present study increases understanding of the the evolutionary relationships between heterotrophic orchid and autotrophic plants.
Lottery Ticket Search on Untrained Models With Applied Lottery Sample Selection
Authors: Bluteau Ryan , Gras Robin
Published: February 2023

In our recent paper [1] we presented leading results in tabular datasets by applying the lottery ticket hypothesis to tabular neural networks. However, we were required to train the original large-sized model to find these lottery tickets. In this paper we eliminate the need to train the original model and discover lottery tickets using networks a fraction of the model’s size. Moreover, we show that we can remove up to 95% of the training dataset to discover lottery tickets, while still maintaining similar accuracy. The approach uses a genetic algorithm (GA) to train candidate pruned models by encoding the nodes of the original model for selection measured by performance and weight met-rics. We found that the search process does not require a large portion of the training data, but when the final pruned model is selected it can be retrained on the full dataset, even if it is often not required. We propose a lottery sample hypothesis similar to the lottery ticket hypotheses where a subsample of lottery samples of the training set can train a model with equivalent performance to the original dataset. We show that the combination of finding lottery samples alongside lottery tickets can allow for faster searches and greater accuracy.
A comparative study of robotic surgery and thoracoscopic surgery for mediastinal cysts
Authors: Hong Ziqiang , Sheng Yannan , Cui Baiqiang , Bai Xiangdou , Cheng Tao , Lu Yingjie , Wu Xusheng , Jin Dacheng , Gou Yunjiu
Published: February 2023

Objective: To compare the efficacy and safety of robotic-assisted thoracoscopic surgery (RATS) with video-assisted thoracoscopic surgery (VATS) in the treatment of mediastinal cysts.
Methods: Retrospective analysis on clinical data of 70 cases of minimally invasive surgery for mediastinal cysts completed in the Department of Thoracic Surgery, Gansu Provincial People's Hospital from April 2014 to December 2022. There were 34 cases in the RATS group with a cyst diameter of (3.70±1.16) cm and 36 cases in the VATS group with a cyst diameter of (4.07±1.20) cm. All cysts were evaluated preoperatively using MRI or chest CT localization. Surgery-related indices were compared among the two groups.
Results: All patients in both two groups successfully completed resection of mediastinal cysts without perioperative deaths. Compared with the VATS group, the RATS group possessed shorter operative time [(75.32±17.80) min vs. (102.22±19.80) min, P<0.001], lesser intraoperative bleeding [(10.29±6.39) ml vs. ±1.37) ml vs. (3.08±1.08) ml, P=0.004], and shorter postoperative hospital stay [(3.26±1.36) d vs. (4.64±1.13) d, P=0.001]. There was no statistically significant discrepancy in intermediate openings and complications in both two groups (P>0.05).
Conclusion: Compared with VATS, RATS is safer and more effective in the treatment of mediastinal cysts and thus has advantages in operative time, intraoperative bleeding, postoperative chest drainage time and postoperative hospital stay.
Cytogenetic profiles of a large cohort of patients with sexual developmental disorders; A 22-year single-center experience
Authors: Demirhan Osman
Published: February 2023

Background
Disorders of Sex Development (DSD) are rare and variable disorders that result from abnormalities in karyotype, gonadal formation, androgen synthesis and androgen action. It is important that newborns with gender ambiguity should be evaluated urgently, and then the etiology should be determined by karyotype and hormone analysis.
Objective
The aim of this study is to determine the frequency and structure of cromosomal abnormalities (CAs) seen in patients with the clinical findings of ambiguous genitalia (AG), hypogonadism (HG), intersex (IS), hypospadias (HS), testicular feminization (TF) and vaginal hypoplasia (VH) between 1990 and 2012.
Materials and Methods
We investigated 85 patients which referred to our department. For chromosome analysis, peripheral blood samples were cultured, harvested and banded according to standard methods.
Results
Percentage rates of 117 patients were 53.8%, 27.4%, 8.5%, 5.1%, 3.4% and 1.7%, respectively, having AG, HG, HS, IS, TF and VH irregularities. Of the patients, 64.9% had normal karyotype and 35.1% had abnormal chromosome setup. In 17 (15.3%) of all patients, the phenotypic sex did not match with the genotypic sex (46,XX; 46,XY). Sex-chromosome mismatch chimerism was found in 7 patients (6.0%) (46,XX/46,XY chimeric individuals). Sex chromosome mismatch chimerism was detected in seven patients (5.9%). Sixteen (13.7%) of all patients had mosaicism of the sex chromosomes. Structural abnormalities were found in gonosomal and autosomal chromosomes in 8 patients (6.3%)
Conclusion
The present date shows that CAs play a role in 38.9% of 85 patients with DSD. Molecular and hormonal techniques may also need to be performed in patients whose genotype-phenotype correlations cannot be made in other patients. It also shows that patients with mosaic cytogenetic findings may actually have chimerism and it is difficult to predict the clinical outcome in these patients.
Anxiety, positive anti-SSA/RO52 antibodies, and anti-histone antibodies are putative risk factors for sleep disorders in patients with systemic lupus erythematosus
Authors: Chen Jinxia , Deng Tongliang , Xu Yongzhi , Liu Huafeng , Xie Tong
Published: February 2023

Sleep disorders are prevalent in patients with systemic lupus erythematosus (SLE) and result in an increased risk of chronic diseases, alter host defense and immune mechanisms, and impact the quality of life and cognitive function. Therefore, we explored the risk factors for sleep disorders in patients with SLE to aid the early screening of patients to facilitate early intervention. Patients admitted to the Department of Rheumatology and Immunology, Affiliated Hospital of Guangdong Medical University, from January 2020 to January 2022, and met the inclusion criteria, were enrolled in our study. Pittsburgh Sleep Quality Index (PSQI) scores were used to divide patients into control group (CG; PSQI ≤ 7) and sleep disorder group (SDG; PSQI > 7). A multifactorial binary logistic regression analysis model was used to analyze the risk factors, including demographic characteristics, clinical data, laboratory test results, and psychological and fatigue status. Among the enrolled 203 SLE patients (mean age, 32.2 ± 8.4 years; 11 men and 192 women), 92 cases (45.32%) had sleep disorders. The SDG had more patients living in rural areas, married, unemployed, chronic illness, arthralgia, depression, anxiety, and no fatigue (all P < 0.05); they also had a relatively low hemoglobin concentration (P = 0.005), and elevated anti-histone, anti-SSA/RO60, and anti-SSA/R052 antibodies (P < 0.05). Fatigue (hazard ratio [HR] = 0.41, P = 0.007) was a protective factor, and anxiety (HR = 14.86, P = 0.001), positive anti-SSA/RO52 antibody (HR = 2.71, P = 0.002), and anti-histone antibody (HR = 2.24, P = 0.023) were independent risk factors. Collectively, we concluded that anxiety and positive anti-SSA/RO52 and anti-histone antibodies are independent risk factors for sleep disorders in patients with SLE.
Connection Between Knowledge Management Processes and Sustainability at the Higher Education Institutions
Authors: Budur Taylan , Abdullah Hariem , Rashid Chnar Abdullah , Demirer Halil
Published: February 2023

Purpose— This study attempts to investigate the connection between knowledge management processes and organizational sustainability in higher education sector of a developing region. It is also planned to examine the moderating effect of online trainings in the relationship between knowledge management and college sustainability.
Design, methodology, approach— Data for the study was gathered from several private and public universities in the Kurdistan Region using a survey questionnaire and a random sample technique. The proposed model has been evaluated using 165 appropriate responses. The demographics of the sample is covered by methodology, along with confirmatory factor analysis, structural equation modelling, mediation, and moderation analysis.
Findings— The findings confirm that knowledge codification/storage and knowledge generation have relatively stronger effects on sustainability of the higher education institutions in the Region. Further, staff trainings increase the understanding of the knowledge management processes that knowledge utilization positively boost sustainability of the institutions through moderation of the workshops. It is also found that knowledge creation and development have a favorable direct effect on other knowledge management processes, implying that higher education institutions should utilize appropriate tools to collect and generate information in order to enhance other KM tools.
Originality/value— The results of this study potentially expand the understanding of the knowledge management processes and their effects on the sustainability at the universities of developing countries, specifically, a developing region that attempts to parallel its higher education system with the contemporary developments in the field.
Effect genotoxic, mutagenic and modulate the proteome from the exposition of alternative fuels.
Authors: Londoño Maritza , Isaza Juan Pablo , Trujillo isabel Cristina Ortiz , lópez Juan Bautista , Pedroza Nini Johanna , Vélez veronica Estrada
Published: February 2023

To determine the genotoxic, mutagenic effect and the ability to modulate the organic material extractable from diesel particulate matter mixed with alcohols (10% ethanol and butanol) (MOE), DNA damage was evaluated through the comet assay and mutagenicity. Using the AMES test on Salmonella typhimurium, proteomic analysis was carried out by extracting total proteins from cell cultures, integrity was assessed by one-dimensional (1D) electrophoresis, and protein profiles were obtained by two-dimensional (2D) electrophoresis. Image analysis in PDQuest reflected differentially expressed proteins which were characterized by mass spectrometry (MALDI-TOF/TOF), the protein-protein interaction network was identified with the STRING database, followed by complex detection analysis. through which it was possible to clarify the cell phones involved. The results showed that MOE caused DNA damage and mutagenicity in bacteria, and the Cox5A, TPI1, PRDX2, ERP29 and PDIA3 proteins were overexpressed and involved in processes related to oxidative stress and oxidative detoxification. In conclusion, exposure to these treatments modulates the proteome of the HepG2 cell line, evidencing detoxification processes at the cellular level.