bluuebunny/crossref_metadata_2025 huggingface dataset:
Differing brain structural correlates of familial and environmental risk for major depressive disorder revealed by a combined VBM/pattern recognition approach
Authors: Opel N. , Zwanzger P. , Redlich R. , Grotegerd D. , Dohm K. , Arolt V. , Heindel W. , Kugel H. , Dannlowski U.
Published: September 2015

Background

Neuroimaging traits of either familial or environmental risk for major depressive disorder (MDD) have been interpreted as possibly useful vulnerability markers. However, the simultaneous occurrence of familial and environmental risk might prove to be a major obstacle in the attempt of recent studies to confine the precise impact of each of these conditions on brain structure. Moreover, the exclusive use of group-level analyses does not permit prediction of individual illness risk which would be the basic requirement for the clinical application of imaging vulnerability markers. Hence, we aimed to distinguish between brain structural characteristics of familial predisposition and environmental stress by using both group- and individual-level analyses.

Method

We investigated grey matter alterations between 20 healthy control subjects (HC) and 20 MDD patients; 16 healthy first-degree relatives of MDD patients (FH+) and 20 healthy subjects exposed to former childhood maltreatment (CM+) by using a combined VBM/pattern recognition approach.

Results

We found similar grey matter reductions in the insula and the orbitofrontal cortex in patients and FH+ subjects and in the hippocampus in patients and CM+ subjects. No direct overlap in grey matter alterations was found between FH+ and CM+ subjects. Pattern classification successfully detected subjects at risk for the disease even by strictly focusing on morphological traits of MDD.

Conclusions

Familial and environmental risk factors for MDD are associated with differing morphometric anomalies. Pattern recognition might be a promising instrument in the search for and future application of vulnerability markers for MDD.
Retrieval of an intra-cardiac embolised very long wire via transhepatic access from a war victim child
Authors: Baspinar Osman , Sahin Derya A. , Yildirim Ali
Published: September 2015

We present the case report of a war victim child with severe burn scars, orthopnoea, and dyspnoea due to diffuse pulmonary thromboembolism. During ICU stay, a central venous catheter’s 45-mm wire embolised into the heart. The embolised wire was successfully removed via transhepatic access through the creation of an artificial simple snare.
A meta-analysis of the validity of FFQ targeted to adolescents
Authors: Tabacchi Garden , Filippi Anna Rita , Amodio Emanuele , Jemni Monèm , Bianco Antonino , Firenze Alberto , Mammina Caterina
Published: September 2015

Objective

The present work is aimed at meta-analysing validity studies of FFQ for adolescents, to investigate their overall accuracy and variables that can affect it negatively.

Design

A meta-analysis of sixteen original articles was performed within the ASSO Project (Adolescents and Surveillance System in the Obesity prevention).

Setting

The articles assessed the validity of FFQ for adolescents, compared with food records or 24 h recalls, with regard to energy and nutrient intakes.

Subjects

Pearson’s or Spearman’s correlation coefficients, means/standard deviations, kappa agreement, percentiles and mean differences/limits of agreement (Bland–Altman method) were extracted. Pooled estimates were calculated and heterogeneity tested for correlation coefficients and means/standard deviations. A subgroup analysis assessed variables influencing FFQ accuracy.

Results

An overall fair/high correlation between FFQ and reference method was found; a good agreement, measured through the intake mean comparison for all nutrients except sugar, carotene and K, was observed. Kappa values showed fair/moderate agreement; an overall good ability to rank adolescents according to energy and nutrient intakes was evidenced by data of percentiles; absolute validity was not confirmed by mean differences/limits of agreement. Interviewer administration mode, consumption interval of the previous year/6 months and high number of food items are major contributors to heterogeneity and thus can reduce FFQ accuracy.

Conclusions

The meta-analysis shows that FFQ are accurate tools for collecting data and could be used for ranking adolescents in terms of energy and nutrient intakes. It suggests how the design and the validation of a new FFQ should be addressed.
Judgments as Public Information
Authors: Magrath Paul
Published: September 2015

This article is written by Paul Magrath who is the Head of Product Development and Online Content at the Incorporated Council of Law Reporting for England and Wales (ICLR). His article explores the issues surrounding the custodianship of those public legal documents, such as court judgments, which form primary sources of law but which may also contain private data, and looks at the way custodians of such data can also act as gatekeepers, enhancing or inhibiting access by the public as well as more specialised users. It expands upon an article published by Infolaw.co.uk entitled “Custodians and gatekeepers: maintaining access to public legal information”, and refers to recent case law involving the tension between information in the public domain and the individual's privacy and “right to be forgotten” by search engines. The article also looks at how court documents are made accessible in other jurisdictions and imagines how things might be improved in our own courts, before concluding that the model of a not-for-profit organisation, such as the ICLR or BAILII (the British and Irish Legal Information Institute), may work as well if not better than public or private management of judgments and other legal public information.
The Cost Exemption in the Freedom of Information Regimes of the United Kingdom and Scotland: a Comparative Analysis
Authors: Liddle Calum , McMenemy David
Published: September 2015

In this tenth anniversary year since freedom of information came into force north and south of the border, the authors, Calum Liddle and David McMenemy, undertake an in-depth comparative evaluation of the parallel cost exemptions found in the Freedom of Information Act 2000 and the Freedom of Information (Scotland) Act 2002. Does Scottish FOI indeed afford a more generous disclosure entitlement? And are applicants, in turn, employing comparatively weaker rights when requesting information from analogous English and Welsh authorities? A statutory analysis of the home nation provisions is complemented by case law and a nod to contemporaneous events.
Post-WagnerianKlangempfindungen: The Premieres of Maeterlinck Operas in Vienna
Authors: Payette Jessica
Published: September 2015

The Viennese premieres of Dukas’sAriane et Barbe-bleueand Debussy’sPelléas et Mélisandein 1908 and 1911 occurred over a decade after Maeterlinck’s literary style and Fernand Khnopff’s paintings were praised by Secessionist critics, including Hermann Bahr and Ludwig Hevesi. In Vienna, fin-de-siècle discourse treats impressionism and symbolism as aesthetic outgrowths of Ernst Mach’s notion of ‘antimetaphysical’ modes of existence. This article explores the broader Viennese reception of symbolism and its influence on music criticism, which predominantly contends that Debussy and Dukas divert from Wagnerian techniques by cultivatingKlangempfindungen(acoustical sensations) and anti-thematic symphonic approaches to generate musical equivalents to the poetic and painterly incitation of psychophysical stimuli. Julius Korngold and other prominent music critics, some of whom were Debussy’s and Dukas’s exact contemporaries, describe how symbolist compositional syntax emerges as a musical terrain that produces a stark contrast between the suspension of latency and frenetic episodes. Symbolist composers accentuate this contrast to increase sensitivity to a literary device at the core of Maeterlinck’s art: the protagonists’ fixation on environmental conditions and changes, descriptive imagery that apprises audiences of their emotional state.
Re-evaluating community policing in a polycentric system
Authors: BOETTKE PETER J. , LEMKE JAYME S. , PALAGASHVILI LIYA
Published: September 2015

Elinor Ostrom and her colleagues in The Workshop in Political Theory and Policy Analysis at Indiana University in Bloomington conducted fieldwork in metropolitan police departments across the United States. Their findings in support of community policing dealt a blow to the popular belief that consolidation and centralization of services was the only way to effectively provide citizens with public goods. However, subsequent empirical literature suggests that the widespread implementation of community policing has been generally ineffective and in many ways unsustainable. We argue that the failures are the result of strategic interplay between federal, state, and local law enforcement agencies that has resulted in the prioritization of federal over community initiatives, the militarization of domestic police, and the erosion of genuine community-police partnerships.
The historian's craft and economics
Authors: HANSEN BRADLEY A. , HANSEN MARY ESCHELBACH
Published: September 2015

History refers both to the past and to the systematic study of the past. Attempts to make a case for history in economics generally emphasize the first definition. There are benefits from increased attention to the past. This paper argues that significant benefits can be gained from increased attention to the systematic study of the past, the historian's craft. The essence of the historian's craft is the critical evaluation of sources. Failure to critically evaluate sources has the potential to lead to erroneous conclusions, whether one is using historical documents or more recently created data.
Autophagy regulates hepatocyte identity and epithelial-to-mesenchymal and mesenchymal-to-epithelial transitions promoting Snail degradation
Authors: Grassi G , Di Caprio G , Santangelo L , Fimia G M , Cozzolino A M , Komatsu M , Ippolito G , Tripodi M , Alonzi T
Published: September 2015

Epithelial-to-mesenchymal transition (EMT) and the reverse process mesenchymal-to-epithelial transition (MET) are events involved in development, wound healing and stem cell behaviour and contribute pathologically to cancer progression. The identification of the molecular mechanisms underlying these phenotypic conversions in hepatocytes are fundamental to design specific therapeutic strategies aimed at optimising liver repair. The role of autophagy in EMT/MET processes of hepatocytes was investigated in liver-specific autophagy-deficient mice (Alb-Cre;ATG7fl/fl) and using the nontumorigenic immortalised hepatocytes cell line MMH. Autophagy deficiency in vivo reduces epithelial markers' expression and increases the levels of mesenchymal markers. These alterations are associated with an increased protein level of the EMT master regulator Snail, without transcriptional induction. Interestingly, we found that autophagy degrades Snail in a p62/SQSTM1 (Sequestosome-1)-dependent manner. Moreover, accordingly to a pro-epithelial function, we observed that autophagy stimulation strongly affects EMT progression, whereas it is necessary for MET. Finally, we found that the EMT induced by TGFβ affects the autophagy flux, indicating that these processes regulate each other. Overall, we found that autophagy regulates the phenotype plasticity of hepatocytes promoting their epithelial identity through the inhibition of the mesenchymal programme.
Large-scale models of signal propagation in human cells derived from discovery phosphoproteomic data
Authors: Terfve Camille D. A. , Wilkes Edmund H. , Casado Pedro , Cutillas Pedro R. , Saez-Rodriguez Julio
Published: September 2015

Mass spectrometry is widely used to probe the proteome and its modifications in an untargeted manner, with unrivalled coverage. Applied to phosphoproteomics, it has tremendous potential to interrogate phospho-signalling and its therapeutic implications. However, this task is complicated by issues of undersampling of the phosphoproteome and challenges stemming from its high-content but low-sample-throughput nature. Hence, methods using such data to reconstruct signalling networks have been limited to restricted data sets and insights (for example, groups of kinases likely to be active in a sample). We propose a new method to handle high-content discovery phosphoproteomics data on perturbation by putting it in the context of kinase/phosphatase-substrate knowledge, from which we derive and train logic models. We show, on a data set obtained through perturbations of cancer cells with small-molecule inhibitors, that this method can study the targets and effects of kinase inhibitors, and reconcile insights obtained from multiple data sets, a common issue with these data.
Blood coagulation protein fibrinogen promotes autoimmunity and demyelination via chemokine release and antigen presentation
Authors: Ryu Jae Kyu , Petersen Mark A. , Murray Sara G. , Baeten Kim M. , Meyer-Franke Anke , Chan Justin P. , Vagena Eirini , Bedard Catherine , Machado Michael R. , Coronado Pamela E. Rios , Prod'homme Thomas , Charo Israel F. , Lassmann Hans , Degen Jay L. , Zamvil Scott S. , Akassoglou Katerina
Published: September 2015

Autoimmunity and macrophage recruitment into the central nervous system (CNS) are critical determinants of neuroinflammatory diseases. However, the mechanisms that drive immunological responses targeted to the CNS remain largely unknown. Here we show that fibrinogen, a central blood coagulation protein deposited in the CNS after blood–brain barrier disruption, induces encephalitogenic adaptive immune responses and peripheral macrophage recruitment into the CNS leading to demyelination. Fibrinogen stimulates a unique transcriptional signature in CD11b+antigen-presenting cells inducing the recruitment and local CNS activation of myelin antigen-specific Th1 cells. Fibrinogen depletion reduces Th1 cells in the multiple sclerosis model, experimental autoimmune encephalomyelitis. Major histocompatibility complex (MHC) II-dependent antigen presentation, CXCL10- and CCL2-mediated recruitment of T cells and macrophages, respectively, are required for fibrinogen-induced encephalomyelitis. Inhibition of the fibrinogen receptor CD11b/CD18 protects from all immune and neuropathologic effects. Our results show that the final product of the coagulation cascade is a key determinant of CNS autoimmunity.
High-efficiency reprogramming of fibroblasts into cardiomyocytes requires suppression of pro-fibrotic signalling
Authors: Zhao Yuanbiao , Londono Pilar , Cao Yingqiong , Sharpe Emily J. , Proenza Catherine , O’Rourke Rebecca , Jones Kenneth L. , Jeong Mark Y. , Walker Lori A. , Buttrick Peter M. , McKinsey Timothy A. , Song Kunhua
Published: September 2015

Direct reprogramming of fibroblasts into cardiomyocytes by forced expression of cardiomyogenic factors, GMT (GATA4, Mef2C, Tbx5) or GHMT (GATA4, Hand2, Mef2C, Tbx5), has recently been demonstrated, suggesting a novel therapeutic strategy for cardiac repair. However, current approaches are inefficient. Here we demonstrate that pro-fibrotic signalling potently antagonizes cardiac reprogramming. Remarkably, inhibition of pro-fibrotic signalling using small molecules that target the transforming growth factor-β or Rho-associated kinase pathways converts embryonic fibroblasts into functional cardiomyocyte-like cells, with the efficiency up to 60%. Conversely, overactivation of these pro-fibrotic signalling networks attenuates cardiac reprogramming. Furthermore, inhibition of pro-fibrotic signalling dramatically enhances the kinetics of cardiac reprogramming, with spontaneously contracting cardiomyocytes emerging in less than 2 weeks, as opposed to 4 weeks with GHMT alone. These findings provide new insights into the molecular mechanisms underlying cardiac conversion of fibroblasts and would enhance efforts to generate cardiomyocytes for clinical applications.
Molecular Basis for the Regulation of Transcriptional Coactivator p300 in Myogenic Differentiation
Authors: Chen Jihong , Wang Yingjian , Hamed Munerah , Lacroix Natascha , Li Qiao
Published: September 2015

Skeletal myogenesis is a highly ordered process which specifically depends on the function of transcriptional coactivator p300. Previous studies have established that Akt/protein kinase B (PKB), a positive regulator of p300 in proliferating cells, is also important for proper skeletal muscle development. Nevertheless, it is not clear as to how the p300 is regulated by myogenic signaling events given that both p300 and Akt are involved in many cellular processes. Our studies revealed that the levels of p300 protein are temporally maintained in ligand-enhanced skeletal myocyte development. Interestingly, this maintenance of p300 protein is observed at the stage of myoblast differentiation, which coincides with an increase in Akt phosphorylation. Moreover, regulation of p300 during myoblast differentiation appears to be mediated by Akt signaling. Blunting of p300 impairs myogenic expression and myoblast differentiation. Thus, our data suggests a particular role for Akt in myoblast differentiation through interaction with p300. Our studies also establish the potential of exploiting p300 regulation and Akt activation to decipher the complex signaling cascades involved in skeletal muscle development.
Characterization of exogenous DNA mobility in live cells through fluctuation correlation spectroscopy
Authors: Mieruszynski Stephen , Digman Michelle A. , Gratton Enrico , Jones Mark R
Published: September 2015

The spatial-temporal dynamics of delivered DNA is a critical aspect influencing successful gene delivery. A comprehensive model of DNA lipoplex trafficking through live cells has yet to be demonstrated. Here the bioimaging approaches Raster Image Correlation Spectroscopy (RICS) and image-Means Square Displacement (iMSD) were applied to quantify DNA mechanical dynamics in live cells. DNA lipoplexes formed from DNA with a range of 21 bp to 5.5 kbp exhibited a similar range of motion within the cytoplasm of myoblast cells regardless of size. However, the rate of motion was dictated by the intracellular location and DNA cluster size. This analysis demonstrated that the different transport mechanisms either had a size dependent mobility, including random diffusion, whereas other mechanisms were not influenced by the DNA size such as active transport. The transport mechanisms identified followed a spatial dependence comparable to viral trafficking of non-active transport mechanism upon cellular entry, active transport within the cytoplasm and further inactive transportation along the peri-nuclear region. This study provides the first real-time insight into the trafficking of DNA delivered through lipofection using image-based fluctuation correlation spectroscopy approaches. Thereby, gaining information with single particle sensitivity to develop a deeper understanding of DNA lipoplex delivery through the cell.
Deletion of integrin α7 subunit does not aggravate the phenotype of laminin α2 chain-deficient mice
Authors: Gawlik Kinga I. , Durbeej Madeleine
Published: September 2015

Laminin-211 is a major constituent of the skeletal muscle basement membrane, exerting its biological functions by binding to cell surface receptors integrin α7β1 and dystroglycan (the latter is part of the dystrophin-glycoprotein complex). The importance of these molecules for normal muscle function is underscored by the fact that their respective deficiency leads to different forms of muscular dystrophy with different severity in humans and animal models. We recently demonstrated that laminin α2 chain and members of the dystrophin-glycoprotein complex have overlapping but non-redundant roles despite being part of the same adhesion complex. To analyse whether laminin-211 and integrin α7 subunit have non-redundant functions we generated mice deficient in laminin α2 chain and integrin α7 subunit (dy3K/itga7). We show that lack of both molecules did not exacerbate the severe phenotype of laminin α2-chain deficient animals. They displayed the same weight, survival and dystrophic pattern of muscle biopsy, with similar degree of inflammation and fibrosis. These data suggest that laminin-211 and integrin α7β1 have intersecting roles in skeletal muscle.
InbR, a TetR family regulator, binds with isoniazid and influences multidrug resistance in Mycobacterium bovis BCG
Authors: Yang Min , Gao Chun-Hui , Hu Jialing , Zhao Lei , Huang Qiaoyun , He Zheng-Guo
Published: September 2015

Isoniazid (INH), an anti-tuberculosis (TB) drug, has been widely used for nearly 60 years. However, the pathway through which Mycobacterium tuberculosis responds INH remain largely unclear. In this study, we characterized a novel transcriptional factor, InbR, which is encoded by Rv0275c and belongs to the TetR family, that is directly responsive to INH. Disrupting inbR made mycobacteria more sensitive to INH, whereas overexpressing inbR decreased bacterial susceptibility to the drug. InbR could bind specifically to the upstream region of its own operon at two inverted repeats and act as an auto-repressor. Furthermore, InbR directly bind with INH and the binding reduced InbR’s DNA-binding ability. Interestingly, susceptibilities were also changed by InbR for other anti-TB drugs, such as rifampin, implying that InbR may play a role in multi-drug resistance. Additionally, microarray analyses revealed a portion genes of the inbR regulon have similar expression patterns in inbR-overexpressing strain and INH-treated wild type strain, suggesting that these genes, for example iniBAC, may be responsible to the drug resistance of inbR-overexpressing strain. The regulation of these genes by InbR were further assessed by ChIP-seq assay. InbR may regulate multiple drug resistance of mycobacteria through the regulation of these genes.
Titania may produce abiotic oxygen atmospheres on habitable exoplanets
Authors: Narita Norio , Enomoto Takafumi , Masaoka Shigeyuki , Kusakabe Nobuhiko
Published: September 2015

The search for habitable exoplanets in the Universe is actively ongoing in the field of astronomy. The biggest future milestone is to determine whether life exists on such habitable exoplanets. In that context, oxygen in the atmosphere has been considered strong evidence for the presence of photosynthetic organisms. In this paper, we show that a previously unconsidered photochemical mechanism by titanium (IV) oxide (titania) can produce abiotic oxygen from liquid water under near ultraviolet (NUV) lights on the surface of exoplanets. Titania works as a photocatalyst to dissociate liquid water in this process. This mechanism offers a different source of a possibility of abiotic oxygen in atmospheres of exoplanets from previously considered photodissociation of water vapor in upper atmospheres by extreme ultraviolet (XUV) light. Our order-of-magnitude estimation shows that possible amounts of oxygen produced by this abiotic mechanism can be comparable with or even more than that in the atmosphere of the current Earth, depending on the amount of active surface area for this mechanism. We conclude that titania may act as a potential source of false signs of life on habitable exoplanets.
Early maternal relational traumatic experiences and psychopathological symptoms: a longitudinal study on mother-infant and father-infant interactions
Authors: Tambelli Renata , Cimino Silvia , Cerniglia Luca , Ballarotto Giulia
Published: September 2015

Early maternal relational traumas and psychopathological risk can have an impact on mother-infant interactions. Research has suggested the study of fathers and of their psychological profiles as protection or risk factors. The aim of the paper is to assess the quality of parental interactions during feeding in families with mothers with early traumatic experiences. One hundred thirty-six (N = 136) families were recruited in gynecological clinics: Group A included families with mothers who experienced early sexual/physical abuse; Group B was composed of families with mothers who experienced early emotional abuse or neglect; and Group C comprised healthy controls. The subjects participated in a 10-month longitudinal protocol [at the fourth month of pregnancy (T0), 3 months after child birth (T1) and 6 months after child birth (T2)] that included an observation of mother-infant and father-infant interactions during feeding (Scala di Valutazione dell’Interazione Alimentare [SVIA]) and a self-reporting 90-item Symptom Checklist-Revised (SCL-90-R). Maternal higher rates of depression and early traumatic experiences of neglect and emotional abuse predicted more maladaptive scores on the affective state of the dyad SVIA subscale. Paternal anxiety predicted more severe levels of food refusal in the child during feeding.
Bioinspired, roughness-induced, water and oil super-philic and super-phobic coatings prepared by adaptable layer-by-layer technique
Authors: Brown Philip S. , Bhushan Bharat
Published: September 2015

Coatings with specific surface wetting properties are of interest for anti-fouling, anti-fogging, anti-icing, self-cleaning, anti-smudge and oil-water separation applications. Many previous bioinspired surfaces are of limited use due to a lack of mechanical durability. Here, a layer-by-layer technique is utilized to create coatings with four combinations of water and oil repellency and affinity. An adapted layer-by-layer approach is tailored to yield specific surface properties, resulting in a durable, functional coating. This technique provides necessary flexibility to improve substrate adhesion combined with desirable surface chemistry. Polyelectrolyte binder, SiO2 nanoparticles and silane or fluorosurfactant layers are deposited, combining surface roughness and necessary chemistry to result in four different coatings: superhydrophilic/superoleophilic, superhydrophobic/superoleophilic, superhydrophobic/superoleophobic and superhydrophilic/superoleophobic. The superoleophobic coatings display hexadecane contact angles >150° with tilt angles <5°, whilst the superhydrophobic coatings display water contact angles >160° with tilt angles <2°. One coating combines both oleophobic and hydrophobic properties, whilst others mix and match oil and water repellency and affinity. Coating durability was examined through the use of micro/macrowear experiments. These coatings display transparency acceptable for some applications. Fabrication via this novel combination of techniques results in durable, functional coatings displaying improved performance compared to existing work where either durability or functionality is compromised.
A new enzyme-free quadratic SERS signal amplification approach for circulating microRNA detection in human serum
Authors: Zheng Jing , Ma Dandan , Shi Muling , Bai Junhui , Li Yinhui , Yang Jinfeng , Yang Ronghua
Published: September 2015

In this communication, we proposed a new enzyme-free quadratic SERS signal amplification approach for the ultrasensitive detection of circulating miRNA in human serum.
Synthesis and thermometric properties of shuttle-like Er3+/Yb3+ co-doped NaLa(MoO4)2 microstructures
Authors: He Dong , Guo Chongfeng , Zhou Shaoshuai , Zhang Liangliang , Yang Zheng , Duan Changkui , Yin Min
Published: September 2015

SEM of shuttle-like NaLa(MoO4)2:Yb3+,Er3+ microcrystals, temperature-dependent UC spectra and sensitivity of samples without (A, C) and with (B, D) calcinations.
Spectroscopic evidence of 3-hydroxyflavone sorption within MFI type zeolites: ESIPT and metal complexation
Authors: Moissette A. , Hureau M. , Kokaislova A. , Le Person A. , Cornard J. P. , De Waele I. , Batonneau-Gener I.
Published: September 2015

Due to the possibility of modulating the molecule surrounding, the internal volume of zeolite provides a specific environment to study the photochemical behaviour of 3-hydroxyflavone (3HF) molecules incorporated in the pores.
Depiction of carbohydrate-active enzyme diversity in Caldicellulosiruptor sp. F32 at the genome level reveals insights into distinct polysaccharide degradation features
Authors: Meng Dong-Dong , Ying Yu , Zhang Kun-Di , Lu Ming , Li Fu-Li
Published: September 2015

Diverse and distinctive encoding sequences of CAZyme in the genome of Caldicellulosiruptor sp. F32 enable the deconstruction of unpretreated lignocellulose.
Quantum dot multiplexing for the profiling of cellular receptors
Authors: Lee-Montiel Felipe T. , Li Peter , Imoukhuede P. I.
Published: September 2015

Multicolor Quantum dots multiplexing single cell analysis of membrane receptors for the development of better patient therapies and the advance of personalized medicine.
Universal chitosan-assisted synthesis of Ag-including heterostructured nanocrystals for label-free in situ SERS monitoring
Authors: Cai Kai , Xiao Xiaoyan , Zhang Huan , Lu Zhicheng , Liu Jiawei , Li Qin , Liu Chen , Foda Mohamed F. , Han Heyou
Published: September 2015

We report a universal chitosan-assisted method to synthesize various Ag-including heterostructured nanocrystals.
Growth of nickel silicate nanoplates on reduced graphene oxide as layered nanocomposites for highly reversible lithium storage
Authors: Wang Qian-Qian , Qu Jin , Liu Yuan , Gui Chen-Xi , Hao Shu-Meng , Yu Yunhua , Yu Zhong-Zhen
Published: September 2015

The synthesized two dimensional face-to-face nanocomposite of nickel silicate (NiSiOx)/reduced graphene oxide (RGO) for lithium storage exhibits a high reversible specific capacity of 797 mA h g−1, 806% higher than that of NiSiOx.
Facile production of monodisperse nanoparticles on a liquid surface
Authors: Anantha P. , Cheng T. , Tay Y. Y. , Wong C. C. , Ramanujan R. V.
Published: September 2015

Emergence of monodispersity during particle growth on a liquid substrate is demonstrated.
A catalytic chemodosimetric approach for detection of nanomolar cyanide ions in water, blood serum and live cell imaging
Authors: Kumar Rahul , Sandhu Sana , Hundal Geeta , Singh Prabhpreet , Walia Amandeep , Vanita Vanita , Kumar Subodh
Published: September 2015

The nano-molar detection of cyanide in live cell imaging and blood serum has been achieved through cyanide catalysed fluorescence enhancement with a TON between 70 and 360.
Highly functionalisable polythiophene phenylenes
Authors: Chan Eddie Wai Chi , Baek Paul , Barker David , Travas-Sejdic Jadranka
Published: September 2015

The synthesis and properties of novel conducting polymer monomers, and their polymers, based on poly(thiophene phenylenes) (PThP) is described.
pH-Responsive cagelike porous polymer microspheres prepared via consecutive RAFT polymerization induced by γ-ray radiation
Authors: Weng Hanqin , Huang Hanhong , Wang Yusong , Wang Mozhen , Ge Xuewu
Published: September 2015

Poly(acrylic acid)-grafted cagelike polymeric microspheres with distinct pH-responsive release properties were fabricated through a two-step consecutive radiation induced RAFT polymerization.
Facile fabrication of nanostructured NiCo2O4 supported on Ni foam for high performance electrochemical energy storage
Authors: Wang Changhui , Zhang Xiong , Li Chen , Sun Xianzhong , Ma Yanwei
Published: September 2015

Nanostructured NiCo2O4 supported on Ni foam with high electrochemical performance was fabricated via a green and low-temperature technique for energy storage.
Synthesis of conductive magnetic nickel microspheres and their applications in anisotropic conductive film and water treatment
Authors: Yu Bing , Zhai Feng , Cong Hailin , Wang Dong , Peng Qiaohong , Yang Shijing , Yang Ruixia
Published: September 2015

Synthesized conductive magnetic Ni microspheres not only can be used for anisotropic conductive films, but also can be used for rapid waste removal and detoxification extraction with a very simple and efficient procedure.
Green fabrication of porous silk fibroin/graphene oxide hybrid scaffolds for bone tissue engineering
Authors: Wang Lu , Lu Chunxiang , Li Yonghong , Wu Feng , Zhao Bin , Dong Xiaozhong
Published: September 2015

The porous SF/GO scaffolds with moderate GO content could promote the proliferation of osteoblasts.
Pestalotriols A and B, new spiro[2.5]octane derivatives from the endophytic fungus Pestalotiopsis fici
Authors: Liu Ling , Zhao Chen , Li Li , Guo Liangdong , Che Yongsheng
Published: September 2015

The endophytic fungus Pestalotiopsis fici produced pestalotriols A (1) and B (2) possessing the unique spiro[2.5]octane skeleton.
Benzodithieno-imidazole based π-conjugated fluorescent polymer probe for selective sensing of Cu2+
Authors: Giri Dipanjan , Patra Sanjib K
Published: September 2015

A benzodithieno-imidazole based π-conjugated fluorescent polymer probe shows excellent selectivity towards Cu2+ions through fluorescence quenching.
Confining the polymerization of aniline to generate yolk–shell polyaniline@SiO2 nanostructures
Authors: Li Xiaoting , Liu Xianchun , Qiao Xiaoguang , Xing Shuangxi
Published: September 2015

Yolk–shell nanostructured polyaniline@SiO2 particles were fabricated by using CeO2@SiO2 particles as reactive and confined templates and the samples were applied in drug loading and photothermal release as a proof of concept.
In situ incorporation of a S, N doped carbon/sulfur composite for lithium sulfur batteries
Authors: Yang Zhigao , Dai Yu , Wang Shengping , Cheng Hong , Yu Jingxian
Published: September 2015

A novel sulfur–nitrogen co-doped carbon material (SNC), which is obtained by taking polyaniline as the nitrogen-containing carbon precursor and then incorporating sulfur atomsin situas the matrix material for lithium sulfur batteries, is investigated.
H-bond supported coordination polymers of transition metal sulfites with different dimensionalities
Authors: Tiwari Ranjay K. , Kumar Jitendra , Behera J. N.
Published: September 2015

Three novel transition metal–sulfite coordination complexes are synthesized using different amines and the role of H-bonding to provide structures with different dimensionalities are discussed.
ortho-Alkenylation of anilines with aromatic terminal alkynes over nanosized zeolite beta
Authors: Mameda Naresh , Peraka Swamy , Kodumuri Srujana , Chevella Durgaiah , Marri Mahender Reddy , Nama Narender
Published: September 2015

Synthesis of 1,1-diarylethylenes derivatives from anilines and aromatic terminal alkynes over a nanosized zeolite beta catalyst is reported.
A high-throughput synthesis of 1,2,4-oxadiazole and 1,2,4-triazole libraries in a continuous flow reactor
Authors: Bogdan Andrew R. , Wang Ying
Published: September 2015

We report herein a high-throughput methodology for the synthesis of 1,2,4-oxadiazole and 1,2,4-triazole small-molecule libraries using an integrated synthesis and purification platform.
Observation of the single-ion magnet behavior of d8 ions on two-coordinate Co(i)–NHC complexes
Authors: Meng Yin-Shan , Mo Zhenbo , Wang Bing-Wu , Zhang Yi-Quan , Deng Liang , Gao Song
Published: September 2015

The first single-ion magnet (SIM) [Co(IMes)2][BPh4] (IMes: 1,3-dimesitylimidazol-2-ylidene) with d8 electronic configuration has been found in two-coordinate Co(i)–NHC complexes.
Target-fueled DNA walker for highly selective miRNA detection
Authors: Wang Lida , Deng Ruijie , Li Jinghong
Published: September 2015

We report a DNA walking biosensor that can realize the detection of let-7a with a detection limit of 58 fM and high selectivity for resolving one nucleotide variation.
Graphene hydrogels non-covalently functionalized with alizarin: an ideal electrode material for symmetric supercapacitors
Authors: An Ning , An Yufeng , Hu Zhongai , Guo Bingshu , Yang Yuying , Lei Ziqiang
Published: September 2015

Alizarin (AZ) with a multi-electron redox center is selected to functionalize three-dimensional self-assembled graphene hydrogels (SGHs) through non-covalent modification and the electrode material shows a good self-synergy and potential self-matching behavior.
Efficient suppression of back electron/hole recombination in cobalt phosphate surface-modified undoped bismuth vanadate photoanodes
Authors: Ma Yimeng , Le Formal Florian , Kafizas Andreas , Pendlebury Stephanie R. , Durrant James R.
Published: September 2015

BiVO4/CoPi photoanodes are studied using transient absorption spectroscopy and transient photocurrent methods. The cathodic shift of photocurrent onset potential is due to efficient suppression of back electron/hole recombination on the timescale of seconds.
Nanoflower-like metallic conductive MoO2 as a high-performance non-precious metal electrocatalyst for the hydrogen evolution reaction
Authors: Jin Yanshuo , Shen Pei Kang
Published: September 2015

The nanoflower-like MoO2 has been synthesized and the material shows high stability and activity toward hydrogen evolution with an onset potential of almost 0V versus the reversible hydrogen electrode (RHE).
A toolkit for bioimaging using near-infrared AgInS2/ZnS quantum dots
Authors: Shamirian Armen , Appelbe Oliver , Zhang Qingbei , Ganesh Balaji , Kron Stephen J. , Snee Preston T.
Published: September 2015

Cadmium free near-infrared AgInS2/ZnS quantum dots have been synthesized and used for imaging the microenvironment of cancer tumours.
Existence and design of non‐overshoot reset controllers for minimum‐phase linear single‐input single‐output systems
Authors: Zhao Guanglei , Wang Jingcheng
Published: September 2015

This study considers the use of reset control to achieve non‐overshoot step response for minimum‐phase linear single‐input single‐output systems. Novel reset controllers with state‐dependent reset conditions are proposed to asymptotically track a constant step reference with zero overshoot, and rise time can be arbitrarily tuned with mild assumption. Moreover, the existence of such non‐overshoot reset controllers is also presented. The proposed design method can also be used for a class of input–output linearisable non‐linear systems and set point regulation. Simulation examples support authors’ results.
A reappraisal of the generic concepts of Epacris, Rupicola and Budawangia (Ericaceae, Epacridoideae, Epacrideae) based on phylogenetic analysis of morphological and molecular data
Authors: Quinn Christopher J. , Crowden Ronald K. , Brown Elizabeth A. , Southam Michael J. , Thornhill Andrew H. , Crayn Darren M.
Published: September 2015

The genus Epacris Cav. (Ericaceae, Epacridoideae, Epacrideae) contains 46 species in south-eastern Australia and two species in New Zealand. Two small genera, Rupicola Maiden & Betche (four spp.) and Budawangia I.Telford (monotypic), both having restricted distributions in the mountains of central eastern New South Wales, have been generally regarded as closely related to but distinct from Epacris. We tested the monophyly and relationships of these three genera using parsimony and Bayesian analysis of morphological and plastid atpB–rbcL DNA sequence datasets. Separate and combined analyses all place Budawangia and Rupicola within Epacris with moderate to strong support. We conclude that there are insufficient grounds for maintaining Rupicola and Budawangia as distinct from Epacris. The required nomenclatural changes are made herein.
Examining range disjunctions in Australian Terminalia (Combretaceae) with taxonomic revision of the T. canescens and T. cunninghamii species complexes
Authors: Barrett Russell L.
Published: September 2015

Several range disjunctions have been identified in the Australian species of the genus Terminalia L. Field studies and examination of herbarium specimens of taxa with range disjunctions have demonstrated that taxonomic changes are justified. Detailed morphological studies of the Terminalia canescens (DC.) Radlk. species complex showed that four taxa should be recognised. The name Terminalia circumalata F.Muell. is resurrected as a taxon endemic to the Pilbara region, with T. canescens not occurring in that region. The distinction of Terminalia bursarina F.Muell., T. canescens and T. pterocarya F.Muell. is also supported. Terminalia cunninghamii C.A.Gardner has been considered to have a disjunct range between the far north and south-west of the Kimberley region of Western Australia. Terminalia kumpaja R.L.Barrett is described as a new species to accommodate the disjunct southern populations because morphological examination has shown them to be distinct. Terminalia kumpaja is restricted to the Dampier Botanical District. Full descriptions and illustrations of key identifying features are provided for these species. Keys to all Australian Terminalia species are presented. Additional species with disjunct distributions that warrant further study are noted. Lectotypes are selected for Terminalia circumalata and T. rogersii W.Fitzg.
Traversativity and grammaticalization
Authors: Tantucci Vittorio
Published: September 2015

This paper discusses the new aktionsart of traversativity, here defined as the category marking the phase of ‘getting-through’ an event or a situation. Different from completives and resultatives (cf. Bybee et al. 1994), traversatives do not profile a phasal contiguity with the telos of a situation, and thus detach the actionality of the event from a subsequent resultant phase. This entails that, along a perfective cline of change, the aktionsart of traversatives triggers aspectual discontinuity or anti-resultativity (cf. Plungian & van der Auwera 2006). Drawing on this, the present work focuses on the grammaticalization of the traversative particle 过guòin Mandarin Chinese towards experiential perfect (cf. Cao 1995, Lin 2004, Liu 2009) and interpersonal evidential (IE) usages (cf. Tantucci 2013, 2014a, 2014b). I argue that the experiential and evidential reanalyses V-过guòare semantically and pragmatically prompted by the original traversative aktionsart of the particle 过guò. I further discuss this phenomenon through a quantitative and qualitative corpus analysis shedding light on the correspondence between specific written genres and the synchronic employment of V-过guòeither as a phasal, an experiential or an interpersonal evidential (IE) marker. Finally, I suggest that actional discontinuity or anti-resultativity constitutes a productive semantic-pragmatic trigger of further evidential reanalyses of a construction.
Appraisal and the language of wine appreciation
Authors: Hommerberg Charlotte , Don Alexanne
Published: September 2015

This paper explores the language used by critics to appraise wine, at the same time investigating the validity and usefulness of categories in the Appraisal framework, as set out by Martin & White (2005). Our analysis of a corpus of wine reviews suggests that sub-categories of Appreciation — used to evaluate products, and non-human targets by reference to aesthetics and other values — may need extending or enhancing in terms of delicacy, depending on the register of the texts under investigation. An adapted version of the Appraisal system of Attitude is used as basis for our investigation. The assessment of our adapted model was carried out in the form of a comparison between two analysts’ independent annotations which function as a basis for a critical discussion of the proposed categories. The bulk of the paper discusses the relevance of our findings for the analysis of specialised genres in general, the field of wine criticism in particular and the application of the Appraisal model for discourse analysis. We conclude that the understanding and application of analytical categories is dependent on the analyst’s previous experience with the Appraisal model as well as acquaintance with the discourse field.
Comparative modals
Authors: Van linden An
Published: September 2015

This article examines modal expressions with the comparative adverbsbetter,ratherandsoonerin American English, and assesses to what extent they have grammaticalized. The corpus data offer evidence that the three comparative modal groups exhibit considerable phonetic reduction in the 1810–2009 period studied. Analysis of several aspects of the constructions, such as subject types, temporal reference and comparative meaning, reveals which conditions promoted this erosion. However, the data also indicate that the three groups are semantically and constructionally quite heterogeneous. In fact, this article proposes a grammaticalization scenario for theratherandsoonerstructures that is different from the one posited for thebetterstructures.
Independencia y fórmulas rutinarias
Authors: Alvarado-Ortega M. Belén
Published: September 2015

This article presents an analysis of some phraseological units, conversational routines, according to their independence degree, in order to restructure Sphere III (Corpas, 1996). In this Sphere there are also proverbs and idioms. In an attempt to classify Spanish phraseological units, we have taken as a model the system proposed by Briz and Val.Es.Co. Group (Briz & Grupo Val.Es.Co., 2003, 2014) for conversational segmentation. This system characterizes some statements in terms of different degrees and types of independence, which allow us to restructure Sphere III. This paper adopts a phraseological and pragmatic approach, with examples taken fromCorpus de conversaciones coloquiales(Briz & Grupo Val.Es.Co., 2002).
A tool to analyze oral competence development in EFL textbooks
Authors: Bueno-Alastuey María Camino , Luque Agulló Gloria
Published: September 2015

Even though theCommon European framework of reference for languageshas placed great emphasis on the teaching and learning of oral aspects and there is general agreement about the need to analyze oral competence development through checklists, the inventories developed so far to analyze textbooks are too general, not explicit enough or devote too little space to oral skills. Consequently, there is currently no specific instrument created to evaluate how oral competence is being fostered in English as a Foreign Language textbooks. This paper aims at filling this gap in research by presenting a tool to analyze oral skills development in EFL course books. The checklist was divided in four sections named background information, listening, speaking, and pronunciation, and included quantitative and categorical measures. The tool is presented in an abridged and an extended version to allow for a shorter and a more detailed scrutiny. A preliminary analysis using it showed a highly significant and excellent inter-rater agreement of 0.995 for numerical items and of 0.907 for categorical ones.
Designing a sight translation course for undergraduate T&I students
Authors: Li Xiangdong
Published: September 2015

Sight translation is widely used in the T&I classroom as a pedagogical tool to enhance trainees’ acquisition of interpreting skills and as a communicative tool to prepare trainees for the translation market. Sight translation, as a separate course, or at least as a necessary component of an interpreting course, is increasingly visible in most T&I programs. However, the pedagogy of sight translation is a rarely touched upon topic in the current literature. This article discusses the design of a sight translation course as a stepping stone for interpreting courses in an undergraduate program. Graves’ (2000) course development model is adapted to serve as the framework of course design. Drawing on findings from previous research, the author describes the five initial elements of course design: context definition, articulation of beliefs, content conceptualization, goals and objectives formulation, and course organization. This article aims at inspiring fellow trainers to design sight translation courses and other T&I courses in a scientific and systematic way.