bluuebunny/crossref_metadata_2025 huggingface dataset:
Ungovernable Counter-Conduct: Ivan Illich’s Critique of Governmentality
Authors: Christiaens Tim
Published: October 2023

Within Michel Foucault’s own conceptualization of governmentality, there is little room for something like ‘ungovernable life’. The latter seems to hint at a form of social conduct beyond power-relations, which would offend Foucault’s basic philosophical postulates. I argue that this identification between governmentality and power as such demonstrates a one-sided focus on the history of Western power-relations. By opposing Foucault’s genealogy of governmentality to Ivan Illich’s critical history of government, I delineate indigenous struggles against governmentalization as a form of ungovernable counter-conduct. Throughout his books from the 1970s to 1990s, Illich wrote a critical history of government surprisingly similar to Foucault’s, from the pastorate to modern political economy. However, rather than merely describing this history, Illich argued governmentalization alienated human beings from their autonomy. As a former missionary priest, he criticized the Church’s and modern governments’ attempts to subsume populations under a conduct of conducts. He advocated anticolonial resistance to subsumption under Western governmental regimes. In Illich’s appreciation of decolonized life, an ungovernable form of life can be discovered, which I defend with the example of Zapatismo and indigenous self-government through mandar obedeciendo.
Sails of Tyr. Role of Polysemy in Ezekiel 27:7
Authors: Nadezhkin Alexey M.
Published: October 2023

The article focuses on the problem of inconsistencies in Eze 27:7. The variation in biblical passage arises from the polysemy in the Masoretic text, which has contributed to the development of a large number of variations in translations. The relevance of the article lies in the fact that there are several versions of the verse in Russian, and therefore the task of textual criticism is to establish the genesis of each of them. The author draws attention to the fact that for a comparative study, data from Latin, Syriac and Slavic translations were used. In the course of the research, the author comes to the conclusion that all translators, referring to the studied verse, used overtone translation, and the chosen correspondence of Hebrew words נֵס and מְָפרש was the subject of exegesis, since the translation equivalent corresponded to the image that the author of the translated text imagined. So, in the word מְָפרש in all meanings there is a general idea: it denotes a kind of stretched textile. But what kind of fabric it was depends on the interpretation. Translators from the Hebrew text believe that Eze 27:7 refers to the sail. St. Jerome was the first to reflect this in his translation. The translators following the Septuagint believe that this is linens, while the Syrian translator used the word “decoration” or “clothing,” having seen in the passage a description of the luxurious clothes of inhabitants of Tire.
Death and Life “for the Common Good” in the Petrine Era: Two Sermons of Stefan Yavorsky
Authors:   Ural Federal University named after the First President of Russia B.N. Yeltsin, Popovich Alexey I.
Published: October 2023

The article is a study and publication of autographs of two sermons by Metropolitan of Ryazan and Murom Stefan (Yavorsky) stored in the Russian State Historical Archive (RSHA). The sermons performed both didactic and panegyric functions: 1) sermon on the birthday of Peter the Great in 1709; 2) sermon in 1721 on the anniversary of victory in the Battle of Lesnaya. The work analyzes the ideological content of the works, identifies themes and topoi that combine these words with other sermons of author from the so-called “victorian cycle.” In both sermons, Yavorsky formulates the pro-state idea of “common good” (obshchaia pol’za) (a formula that replaced the idea of common wealth in the Petrine era, discusses the role of people representing different “ranks” in achieving the “common good,” finding in the military rank as a social ideal and a model of virtues, glorifies the sovereign and the state. The sermons published in the article are bright authorial publicistic statements and expand the understanding of Stefan Yavorsky as a writer.
A new standard of mental health: The theory of five dimensions of personality
Authors: Xiyu Li , Chunqiao Li
Published: October 2023

The mental health standard formulated by the World Health Organization
has the insufficiency of single ideal; Based on the factual logic of
human life activities, we put forward the theory of five dimensions of
personality, including ideal dimension, self-return dimension, practical
dimension, prohibitive dimension and in-itself dimension. In the actual
mental health education activities, the theory of five dimensions of
personality can provide us with more operable developmental goals and
corrective techniques.
Blowing-up solutions for the Moore-Gibson-Thompson equation with visco-elastic memory and an external force
Authors: Kirane Mokhtar , ALA DRAIFIA , Lotfi Jlali
Published: October 2023

The Moore-Gibson-Thompson equation with a viscoelastic memory and a
forcing is considered. The existence and uniqueness of a local solution
is obtained via the Faedo-Galerkin’s method. Furthermore, blowing-up
solutions with or without a positive initial energy exist due to the
nonlinear forcing.
Riparian vegetated area in pre-dam, post-dam, and environmental flow periods in Canyonlands National Park from 1940 to 2022
Authors: Perkins Dustin , Wight Aneth , Wondzell Mark , Friedman Jonathan
Published: October 2023

The upper Colorado River is a highly regulated system that provides
habitat for federally listed species, disproportionate number of flora
and fauna and is the water supply for the western United States. River
regulation has led to wide scale channel narrowing. Over the last three
decades dams have been operated with a more natural hydrograph for
environmental reasons. We sought to use remote imagery from 1940-2022 to
examine rates of channel narrowing in the pre-dam, post-dam, and
environmental flows eras along three river reaches in Canyonlands
National Park. We found an increase in the vegetated area along the
Colorado River (above the confluence with the Green River) and the Green
River since 1940. We documented a 6.12% and 4.00% narrowing in the
post-dam period and a 19.51% and 6.49% narrowing in the environmental
flows period on the Colorado and Green Rivers, respectively. The
Cataract Canyon reach (Colorado River below the confluence) has been
stable since 1966. All three river reaches showed the slowest period of
narrowing in the last 16 years of environmental flows that coincided
with a large peakflow in 2011. All three reaches showed a decrease in
vegetated area after the 2011 flood, followed by an increase in
vegetated area to similar levels to before the 2011 flood. Environmental
flows that mimic the natural hydrograph may have slowed channel
narrowing, but it is clear that periodic large peaks are also necessary.
Managers must be careful that any environmental flows that take from the
spring peak are carefully considered.
Dynamic response of Steel-Concrete Beams with Partial Interaction due to moving loads
Authors: Ali Mohamad , Dandachy Mohamad El , Ellakany Ahmed M.
Published: October 2023

Purpose –The main purpose of this paper is to propose a
numerical model which represents dynamic responses of elastic
steel-concrete beams. Design/methodology/approach –The
numerical model is based on the lumped system with the combination of
transfer matrix method (TMM) and analog beam methods (ABM). The beams
which are widely used in constructions of highway bridges are composed
of an upper concrete slab and a lower steel beam, connected at the
interface by shear transmitting studs. The field and point transfer
matrices for the beam element of the elastic composite beams are
derived. The present model is verified and is applied to study the
dynamic response of elastic composite beams subjected to both, moving
force or mass. The effects of shear stiffness between the upper slab and
lower beam and moving load velocity on the steel-concrete beams
deflection are shown. Findings –Results indicate that the
maximum deflection in the composite beam subjected to moving load, is
significantly affected by the level of interaction between sub-beams and
by the load type and velocity. Originality/value – Recently, a
numerical model based on the lumped system with the combination of the
TMM and the ABM was proposed to study the response of elastic
steel-concrete beams with partial interaction, limited to static loading
solely. In this study, the current proposed model is developed to study
the dynamic response of steel-concrete beams with partial interaction
due to moving loads of various velocities. The advantage of the proposed
model, unlike previous models that are based on the combination of (TMM)
and (ABM), is the ability for studying the dynamic behavior of the
elastic steel-concrete beams with various end and intermediate
conditions and different types and velocities of moving loads.
Inverse problems of the wave equation for media with mixed but separated heterogeneous parts
Authors: Kawashita Mishio , Kawashita Wakako
Published: October 2023

In this article, the inverse problems for the wave equation in a medium
in which multiple types of cavities and inclusion exist in a mixture are
considered. From the point of view of the indicator function of the
enclosure method, there are two types of heterogeneous parts:“minus
group” and “plus group”. For example, cavities with the Dirichlet
boundary condition belong to the minus group, while inclusions with
smaller propagation velocity belong to the plus group. The heterogeneous
part of the minus group gives a negative sign to the indicator function,
and the heterogeneous part of the plus group gives a positive sign. In
general, the presence of many types of heterogeneous parts causes
cancellation of the sign of the indicator function. Such cases are
referred to as “mixed cases”. Here we consider the case that the
shortest length obtained from the indicator function is attained only by
heterogeneous parts of the same group. This case is called the “mixed
but separated case” and it is shown that the method of elliptic
estimates developed by Ikehata works well. We also show that the case of
a two-layered background medium with a flat layer can be considered in
the same way as the case of a homogeneous background medium.
Chromosome-scale genome assembly of Lepus oiostolus (Lepus, Leporidae) provides insights into the high levels of ultraviolet radiation
Authors: Feng Shuo , Zhang Yaying , He Zhaotong , Xi Erning , Ru Dafu , Liang Jian , Yang Yongzhi
Published: October 2023

Lepus oiostolus (L. oiostolus) is a species endemic to the Qinghai-Tibet
Plateau. However, the absence of a reference genome limits genetic
studies. Here, we report a high-quality L. oiostolus genome assembly,
with scaffolds anchored to 24 chromosomes and a total assembled length
of 2.80 Gb (contig N50 = 64.24 Mb). We found that transposable elements
account for 49.84% of the genome, a total of 22,295 predicted
protein-coding genes. Long interspersed nuclear elements (LINEs)
constitute a high proportion of the genome, and their expansion is a key
contributor to this species’s relatively large genome size. A total of
1,282 genes were found to have expanded into gene families. Comparative
analyses indicated that L. oiostolus probably diverged from its close
relatives Ochotona curzoniae and Ochotona princeps, approximately 53.1
million years ago (MYA). This study suggested that the Tipin gene
enabled Lepus oiostolus to adapt to the high levels of ultraviolet
radiation in the Qinghai-Tibet Plateau. As the first chromosome-level
genome assembly of Lepus oiostolus, this study will provide a valuable
genomic resource for future research on the evolution of the Leporidae.
The impact of parental and developmental stress on DNA methylation in the avian hypothalamic-pituitary-adrenal axis
Authors: Wilks Stefanie Siller , Heidinger Britt , Westneat David , Solomon Joseph , Rubenstein Dustin
Published: October 2023

The hypothalamic-pituitary-adrenal (HPA) axis coordinates an organism’s
response to environmental stress. The responsiveness and sensitivity of
an offspring’s stress response may be shaped not only by stressors
encountered in an organism’s early post-natal environment, but also by
stressors in their parent’s environment. Yet, few studies have
considered how stressors encountered in both of these early life
environments may function together to impact the developing HPA axis.
Here, we manipulated stressors in the parental and post-natal
environments in a population of house sparrows (Passer domesticus) to
assess the impact of these stressors on changes in DNA methylation in a
suite of genes within the HPA axis. We found that nestlings that
experienced early life stress across both life-history periods had
higher DNA methylation in a critical HPA axis gene, the glucocorticoid
receptor (NR3C1). In addition, we found that the life-history stage when
stress was encountered impacted some genes (HSD11B1, NR3C1, and NR3C2)
differently. We also found evidence for the mitigation of parental
stress by post-natal stress (in HSD11B1 and NR3C2). Finally, by
assessing DNA methylation in both the brain and the blood, we were able
to evaluate cross-tissue patterns; while some differentially methylated
regions were tissue-specific, we found cross-tissue changes in NR3C2 and
NR3C1, suggesting that blood may be a potential biomarker for DNA
methylation of specific genes. Our results provide a crucial first step
in understanding the mechanisms by which early life stress in different
life history periods contributes to changes in the epigenome of the HPA
axis.
Molecular characterization and differentiation of cucumber mosaic virus subgroups in Serbia by RT-PCR-RFLP
Authors: Zecevic Katarina , Stankovic Ivana , Petrovic Branka , Krstic Branka
Published: October 2023

Samples of various host plants from different locations in Serbia showing foliar symptoms resembling those caused by the cucumber mosaic virus (CMV) were collected. Samples were considered CMV-infected after detection by double-antibody sandwich enzyme-linked immunosorbent assay (DAS-ELISA). Fifteen CMV isolates were selected for developing a reverse transcription-polymerase chain reaction (RT-PCR) restriction fragment length polymorphism (RFLP) protocol and a more detailed molecular characterization of all five genes. Based on in silico RFLP, the following restriction enzymes were selected: HindIII, SacII (1a gene), MluI (2a gene), StuI, SalI (2b gene), BaeI (movement protein (MP) gene of CMV), SfcI, and HaeIII (capsid protein (CP) gene), which were capable of distinguishing between subgroups of CMV based on the obtained characteristic restriction patterns. According to in situ RFLP, the predominant haplotype IA; IA, IA; IA, IA was determined in 14, while the distinct haplotype II; II, II; II, II was found in only one isolate. Sequence analyses of two selected Serbian CMV isolates with different restriction patterns and haplotype profiles confirmed the RFLP results, showing that isolates 674-11 and 137-13 belong to subgroups IA and II, respectively. Different restriction patterns after digestion of all five CMV genomic regions proved to be a simple way to investigate the natural population of CMV. This study provides insight into the genetic structure of the CMV population in Serbia.
Phosphate solubilization and the enhancement of chickpea growth by new rhizospheric microorganisms Bacillus tequilensis and Trichoderma orientale
Authors: Bekkar Ahmed , Zaim Souad
Published: October 2023

Two Trichoderma strains and three Bacillus strains isolated from the rhizosphere of healthy chickpeas in Algeria were assessed for their phosphate solubilizing capacity in vitro as well as their growth effects on seedlings of the chickpea in pot experiments. The microorganisms tested had higher phosphate-solubilizing activities, with the solubilization index ranging from 2.41 to 7.40. The concentration of solubilized phosphate varied from 30.17 to 157.44 ?g/mL. The maximum phosphate-solubilizing activity was observed in the two culture filtrates of Bacillus tequilensis Bt1 (157.44 ?g/mL) and Trichoderma orientale T1 (143.33 ?g/mL), accompanied by a decrease in pH of the growth medium from 4.51 to 5.75. The application of the strains (B. tequilensis Bt1 and T. orientale T1) separately and in combination had a beneficial effect on germination by promoting the development of the seeds and effectively enhancing plant growth. Chickpea seedlings showed better vegetative growth when treated with a mixture of B. tequilensis Bt1 and T. orientale T1 together than an individual treatment. To our knowledge, this is the first report of the phosphate-solubilizing potential of the combined microorganisms B. tequilensis and T. orientale and their capacity to promote plant growth in chickpeas.
Predictive factors of therapeutic response according to craniofacial skeletal biotype in patients with sleep apnea syndrome using mandibular advancement devices: a pilot study
Authors: Navarro Rafael Ecija , Karadede Berşan , Karadede Ünal Beyza , Salvador Domingo Martin
Published: October 2023

Objectives

To evaluate the influence of facial biotype in the therapeutic effect of mandibular advancement devices (MADs) according to polysomnographic records in patients diagnosed with sleep apnea–hypopnea syndrome (SAHS).

Materials and Methods

A total of 46 patients were recruited. Patients were classified according to facial biotype (mesofacial, brachyfacial, or dolichofacial). The quantitative variables were described as the arithmetic mean and standard deviation or the median and interquartile range. Hypothesis tests used were Pearson’s chi-square, paired-sample Student’s t- test, the Wilcoxon test, one-way analysis of variance, Kruskal-Wallis test, and Mann-Whitney U-test. P < .05 was considered statistically significant.

Results

A total of 46 patients were categorized into three facial biotype subgroups with no significant differences among them in age, body mass index, neck circumference, and sex. The respiratory disturbance index (RDI) results were as follows: brachyfacial patients had a reduction to 15 events/h (P < .001), the mesofacial patients had a reduction to 14 events/h (P < .001), and the dolichofacial patients did not show a significant reduction. The oxygen desaturation index (ODI) results were as follows: brachyfacial patients had a reduction in ODI episodes to 45 episodes/h (P = .001), mesofacial patients had a reduction to 18 episodes/h (P = .001). In the brachyfacial group, the number of awakenings with MAD therapy was reduced to 23 events/h (P = .003), while, in the mesofacial group, it was reduced to 37 episodes/h (P = .012).

Conclusions

The facial biotype influences the effectiveness of MAD therapy and is considered a good predictive factor.
DA Motor Kontrolünde Veri Güdümlü ve Model Tabanlı Yöntemlerin Ani Yük Değişimlerine Karşı Tepkilerinin Analizi
Authors: Sonugür Güray
Published: October 2023

Doğru Akım (DA) motor hız denetleyicilerinde bozucu etkilere karşı direnç gösterme ve her türlü dış etki karşısında referans noktasını en az hata ile takip etmek kritik öneme sahiptir. DA motorlarda en sık karşılaşılan bozucu etki ani yük değişimleridir. Bu nedenle denetleyicilerin ani yük değişimlerine karşı hızlı ve etkili bir yanıt oluşturulması ve referans değerden en az sapmayı gerçekleştirmesi gerekir. Bu çalışmada DA motorlarda meydana gelebilecek ani yük değişimlerine karşı model tabanlı ve veri güdümlü yöntemlerin yanıtları analiz edilmiştir. Veri güdümlü kontrol (VGK), denetleyiciyi tasarlamak ve optimize etmek için toplanan giriş-çıkış verilerini kullanan öğrenme tabanlı bir kontrol yöntemidir. Model tabanlı kontrol (MTK) yönteminde ise, kontrol edilecek sistemin matematiksel modeli hesaplanır. Çalışma kapsamında model tabanlı yöntem olarak Oransal-İntegral-Türev (PID), veri güdümlü yöntemler olarak yapay sinir ağları (YSA) ve kontrol süreçlerinde zaman serilerini de dikkate alan dışsal girdili otoregresif sinir ağları (NARX) denetleyiciler incelenmiştir. Böylece DA motor hız kontrolünde model tabanlı, veri güdümlü ve veri güdümlü + zaman serili olmak üzere üç farklı yaklaşımın performansları incelenmiştir. Deneysel çalışmalarda simülasyon değil gerçek motorlar kullanılmış ve deneyler 100 rpm (DAM1) ve 300 rpm (DAM2) hızına sahip kalıcı mıknatıslı DA motorlar kullanılarak gerçek zamanlı olarak gerçekleştirilmiştir. Elde edilen sonuçlar, toplam normalize hata, yükselme zamanı ve maksimum yüzde aşma performans ölçütleri kullanılarak sunulmuş ve yöntemlerin başarılı ve başarısız yönleri tartışılmıştır.
Effect on the Skin Microbiota of Oral Minocycline for Rosacea
Authors: Zhang Yiyi , Zhou Ying , Humbert Philippe , Yuan Dengfeng , Yuan Chao
Published: October 2023

In the rosacea an unstable skin microbiota is significant for disease progression. However, data on the influence on the skin microbiota of treatment with systemic antibiotics are limited. This single-arm trial recruited patients with rosacea. Oral minocycline 50 mg was administered twice daily for 6 weeks. The lesions on the cheek and nose were sampled for 16S rRNA amplicon sequencing and metagenomic sequencing at baseline, 3 weeks and 6 weeks of treatment. Physiological parameters were detected using non-invasive instruments. After treatment, distribution of the Investigator Global Assessment scores changed significantly. For the skin microbiota, a notable increase in α-diversity and a shift of structure were observed after treatment. Treatment was accompanied by a reduction in the relative abundance of Cutibacterium and Staphylococcus, indicating negative correlations with increased bacterial metabolic pathways, such as butyrate synthesis and L-tryptophan degradation. The increased butyrate and tryptophan metabolites would be conducive to inhibiting skin inflammation and promoting skin barrier repair. In addition, the abundance of skin bacterial genes related to tetracycline resistance and multidrug resistance increased notably after antibiotic treatment.
Biomedical Impact of Heavy Metal Ions on Human Health
Authors: Mishra Sanjay
Published: October 2023

Nearly thirty chemical elements are frequently institute in bio-organisms, involving in basic physio-biochemical and functions, and recognized as necessary elements for life.
Targeting Redox Enzymes of Cholesterol Biosynthesis: A Step in the Right Direction Towards Ending Cardiovascular Disease
Authors: Francis Kevin
Published: October 2023

Global occurrence of cardiovascular diseases is a serious health concern resulting in over 2 million deaths annually. A major cause of cardiovascular disease is elevated levels of blood plasma cholesterol which leads to the precipitation of lipoproteins and arterial plaque formation. This review details treatment of hypercholesterolemia that target redox enzymes involved in the biosynthesis of the lipid. It begins with a brief discussion of both high- and low-density lipoproteins that are the vehicles for cholesterol transport in humans. An overview of the five stages of cholesterol anabolism in the liver is then provided focusing on the two rate-limiting redox enzymes involved in the pathway. These enzymes are 3-hydroxy-3-methylglutyl CoA reductase (HMGR) and squalene monooxygenase (SMO). The structure and catalytic mechanisms are presented in great detail to lay the foundation for a presentation of common cholesterol lowering drugs. The first of these are the statins that competitively inhibit HMGR and have shown the greatest success in both the treatment and prevention of cardiovascular diseases. An inhibitor of SMO called terbinafine is then discussed. This drug molecule is a fairly effective anti-fungal but is not currently approved in the U.S. to treat high cholesterol. However, it has been shown to lower low-density lipoproteins and exhibits promise to provide the framework for the development of new cholesterol lowering treatments to target SMO. It is hoped that this review article will raise awareness and spur future research into the treatment of hypercholesterolemia to treat and/or prevent cardiovascular disease.
Development and Evaluation of a Meloxicam Topical Ointment for Localized Drug Delivery
Authors: V Malvade Pratik
Published: October 2023

The introduction of this research paper sheds light on the background and significance of employing topical drug delivery methods to enhance the localized effects of NSAIDs, such as meloxicam. The introductory section underscores the potential benefits of utilizing skin penetration enhancement techniques to augment the efficacy of the ointment. The materials and techniques section comprehensively outlines the constituents employed in the study, including meloxicam and excipients. Special attention is dedicated to ensuring the stability and compatibility of the formulation components, with thorough investigations into drug-excipient interactions. Following the formulation’s development, a meticulous characterization of the ointments is conducted, encompassing their physicochemical attributes and drug release profiles. Concurrently, in vitro skin permeation experiments elucidate meloxicam’s capability to permeate the skin and elicit its therapeutic effects. The resultant characterization data yield valuable insights into the physical characteristics of the ointments. In conclusion, this thesis study substantially advances our comprehension of meloxicam topical ointment formulation development and evaluation for localized drug delivery. The findings gleaned from this study provide invaluable insights into the feasibility and effectiveness of employing a meloxicam-infused ointment. Such an approach holds the promise of offering a compelling alternative to conventional systemic administration, mitigating systemic side effects, and concurrently maximizing the localized therapeutic advantages of meloxicam.
SEEVA para posgrados de la Universidad Santo Tomás, seccional Bucaramanga
Authors: Roncancio Becerra Claudia Yaneth , Torres Velandia Serafín Ángel
Published: October 2023

Los entornos virtuales de enseñanza-aprendizaje (EVA) son recursos ampliamente utilizados en la educación en línea. Para garantizar su efectividad, es esencial que estos sean de alta calidad y sometidos a evaluación. Sin embargo, a pesar de la disponibilidad de diversas herramientas y sistemas de evaluación, aún no existe un enfoque integral que englobe aspectos pedagógicos, técnicos y organizativos. Por eso, en el presente trabajo se propone el Sistema de Evaluación de Entornos de Aprendizaje (SEEVA), el cual fue creado para los EVA de los programas de posgrado de la Universidad Santo Tomás, seccional Bucaramanga. Este se basa en la integración de criterios provenientes de sistemas como HEODAR, minería de datos, FLOE y LORI. Para desarrollarlo, se llevó a cabo un diagnóstico exhaustivo y una valoración de los criterios usados en los referidos sistemas. El resultado generó un marco de evaluación que abarca las tres dimensiones (aspectos pedagógicos, técnicos y organizativos) con criterios y subcriterios detallados. El objetivo fundamental del SEEVA es proporcionar a los EVA un plan de mejora personalizado, lo cual permitirá actualizarlos y optimizarlos según las necesidades específicas del contexto educativo y las últimas tendencias en herramientas digitales.
Seismic Response Characteristics of a Tunnel Portal Subjected to Topographical and Geological Asymmetsric Loading
Authors: Peng F. , Fang S.
Published: October 2023

The tunnel portal is the most seismically vulnerable section of the tunnel against earthquakes. Due to the combined effects of topographic and geological asymmetric loading, the mechanical characteristics of this type of portal are very complex. In this study, a three-dimensional numerical model was developed and calculated to investigate the seismic response characteristics of a tunnel portal subjected to topographic and geological asymmetric loading. The results show that the seismic weakness of the tunnel support structure is located at the tunnel arch shoulders and sidewalls; the time to reach the peak displacement around the tunnel is slightly delayed compared to the slope, and the time to reach the peak displacement shows a phased pattern. Compared to the tunnel structure, the slopes are more prone to landslides and other disasters due to terrain and geological factors under earthquake action. Therefore, more attention should be paid to the seismic and anti-seismic design of tunnel slopes.
Study of Islamic Education Thought in the Perspective of KH. Idham Chalid
Authors: Rahman Arief , Jamalie Zulfa
Published: October 2023

Initially named Arabische School which was educated by KH. Abdurrasyid, then changed its name to Madrasah Rasyidiyah during the time of KH. Juhri Sulaiman. Furthermore, it changed to Ma'had Rasyidiyah during the time of H. M. Arif Lubis and at the time of KH. Idham Chalid changed to Normal Islam and Rasyidiyah Khalidiyah which held the principle of tafaqquh fi ad din (Normal Islam). KH Idham Chalid's efforts as the leader of the Pesantren at Normal Islam were to combine exact lessons and general science as support with a presentation of 60% religious lessons and 40% general lessons using Arabic as an introduction. Context related to the study of Islamic education thought and aspects of advancing Islamic education, especially during the struggle for independence of the Republic of Indonesia. This article uses a literature study with the type of research using qualitative, through this method the facts revealed include heuristic and historigraphy in revealing the history and role of KH. Idham Chalid in the world of education. The purpose of this research is to reveal patterns of thought in the development of Islamic education and the findings obtained are KH. Idham Chalid made reforms in the world of pesantren education related to three aspects, namely improving pesantren institutions, improving the education system, and developing infrastructure
Experimental and Analytical Studies of the Relationship between the Combustibility of Materials and the Parameters of Ignition Sources in the Pressurized Chambers with Oxygen-Enriched Media and at the Elevated Pressure
Authors:   FGBU VNIIPO EMERCOM of Russia, Bolodyan I.A. , Vogman L.P. ,   FGBU VNIIPO EMERCOM of Russia, Korolchenko D.A. ,   National Research Moscow State University of Civil Engineering,   Institute of Integrated Safety in Construction
Published: October 2023

The results are presented related to the experimental and analytical studies of the relationship between the combustibility of materials and the parameters of ignition sources in the equipment with oxygen-enriched media and at an elevated pressure. It is shown that when materials used in the thermal chambers are heated, the temperature of spontaneous ignition increases significantly near combustion limits in terms of oxidant concentration and pressure, and a regime occurs, in which gasification of the sample can take place without ignition. The nature of the ignition of the insulation of the wire and materials depends on the current load. The time from the beginning of the short circuit to the beginning of the pyrolysis process, i.e. before the appearance of smoke, according to the calculations, is inversely dependent on the square of the current strength. The ignition delay time of the materials in the cable composition tends to decrease with increasing current. Moreover, at the same current density, the ignition delay time of materials from a single wire is less than that of a cable even with a current load of four wires. This circumstance and the patterns obtained for the ignition of materials from a single wire allow to conclude that the response time of the current protection for cables can be selected based on the delay time for the ignition of materials from a single wire.
Numerical Identification of Corrosion Indicators when Assessing the Equipment Technical Condition
Authors:   IMASH RAN, Makhutov N.A. , Cherepanov A.P. ,   Angarsk State Technical University, Lisanov M.V. ,   STC «Industrial Safety» CJSC
Published: October 2023

The method is presented in the article concerning numerical identification of corrosion and corrosion resistance of metals, which serves to determine the degree of hazard of the corrosive state of technical devices of hazardous production facilities. Currently, the causes of metal failure are determined by metallography, radiography, ultrasonic, color, magnetic particle inspection or sample testing. Risk of the development of corrosion processes, depending on the type of corrosion, the characteristics of its shape, the depth of corrosion damage and the area of the affected surfaces, is determined visually or by the instrumental detection methods. Numerical identification of the indicators of corrosion and corrosion resistance of metals, proposed in the work, is carried out taking into account the location of the corrosion process, the form of corrosion damage, the size, unevenness and depth of penetration of various types of corrosion, the degree of damage to the surface by uniform and local corrosion (spots, ulcers, pitting). At the same time, according to the initial size of surface and deep corrosion, the actual size of the corrosion wear of a structural element is determined, and according to the scheme of a typical type and characteristic of the form of corrosion damage, the type of corrosion is determined. Further, taking into account the corrosion hazard score in accordance with the scale of corrosion resistance, a numerical indicator of corrosion and corrosion resistance of the structural metal is determined. Studies showed that the numerical identification of the indicators of corrosion and corrosion resistance of metals makes it possible to match the type of corrosion and the characteristics of the form of corrosion damage with the corrosion coefficient depending on the scheme of a typical type of corrosion damage. In addition, numerical identification shows the extent of damage to the surface by uniform and localized corrosion, including spots, pitting and other types of corrosion. Thus, it is applicable to determine the degree of corrosion hazard in assessing the technical condition and establishing the service life at any stage of the life cycle of equipment in hazardous industries.
Development of the Risk Management Methodology at the Fire Explosive Facilities of the Enterprises
Authors:   National Research Moscow State University of Civil Engineering, Gvozdev E.V.
Published: October 2023

The article formulates a new concept for the integrated safety, clarifies the concept for the integrated safety system of explosive production facilities of the enterprises. Aggregated areas with scientific results on risk assessment in the integrated safety of production enterprises was formed. To improve safety at the enterprises under consideration, it was required to solve three problems. To solve the first problem, the current, practical results of the scientific research were analyzed both in Russia and in the foreign countries. It is concluded that the reduction of damage from the impact of hazardous events is to create a reasonable reserve designed to reduce (exclude) various risks, the rational use of the reserve based on the use of an approach developed from a new angle of view in relation to risk. When solving the second problem, the existing methods for assessing the state of the industrial and fire safety subsystems, occupational safety included in the integrated safety system of the enterprises under consideration, as well as a new direction for assessing the state of the integrated safety were presented in comparison. When solving the third problem, a formalized description of a new, different from the used model for improving and developing the integrated safety system for explosive production facilities of the enterprises is presented. The purpose of the assessment is formulated, the new methods and results of the assessment of the state of the integrated safety of these enterprises are presented. As a result, three problems were solved, on their basis the conceptual model for the development of the integrated safety system for explosive production facilities of the enterprises was formed.
COMPLEX REGIONAL PAIN SYNDROME IN CHILDREN: A BIBLIOGRAPHICAL REVIEW AND A PEDIATRIC TRAUMATOLOGIST-ORTHOPEDIST’S CASE REPORT
Authors:   Research Institute of Traumatology, Orthopedics and Neurosurgery with the Saratov State Medical University named after V.I. Razumovsky, Saratov, Russia, Rubashkin S.A. , Sertakova A.V. ,   Research Institute of Traumatology, Orthopedics and Neurosurgery with the Saratov State Medical University named after V.I. Razumovsky, Saratov, Russia, Rubashkin A.S. ,   Saratov State Medical University named after V.I. Razumovsky, Saratov, Russia
Published: October 2023

Complex regional pain syndrome (CRPS) in children has specific features that distinguish it from the adult form. In addition, there are no specific data on possible manifestations, diagnostic criteria and therapeutic aspects of this pathology. Depending on the severity of symptoms, CRPS leads to functional disorders of the body, a decrease in the quality of life. The research includes a case report of a patient with CRPS in the distal segment of the limb (foot); the diagnosis was made 4 months earlier and the patient responded well to the treatment. The Authors also speculate about CRPS determinants. In the reported case, the combination of following factors was revealed: a pathological relationship in the talonavicular and calcaneal junction (vertical talus) making the normal biomechanical movements in the foot impossible; trauma; hypersthenic physique of a child with pronounced subcutaneous fat in the foot as well. No genetic criteria or significant neurological abnormalities were identified in the patient. Undoubtedly, the causes and ways of CRPS occurrence in children should be carefully studied by pediatricians as well as experts in other fields.
INFLIXIMAB IN THE TREATMENT OF IMMUNOGLOBULIN-RESISTANT KAWASAKI DISEASE
Authors:   Morozov Children’s City Clinical Hospital, Moscow, Russia, Kurbanova S.Kh. , Bregel L.V. ,   Irkutsk State Medical Academy of Postgraduate Education, Branch of the Russian Medical Academy for Continuous Professional Education, Irkutsk, Russia, Kurako M.M. ,   Morozov Children’s City Clinical Hospital, Moscow, Russia, Marandzhian A.O. ,   Morozov Children’s City Clinical Hospital, Moscow, Russia, Kantemirova M.G. ,   Morozov Children’s City Clinical Hospital, Moscow, Russia,   Patrice Émery Lumumba People’s Friendship University of Russia, Moscow, Russia, Novikova Yu.Yu. ,   Morozov Children’s City Clinical Hospital, Moscow, Russia,   Patrice Émery Lumumba People’s Friendship University of Russia, Moscow, Russia, Valieva S.I. ,   Morozov Children’s City Clinical Hospital, Moscow, Russia,   Pirogov Russian National Research Medical University, Moscow, Russia
Published: October 2023

Kawasaki disease (KD) is an acute systemic disease characterized by predominant damage to small and medium-sized arteries with the development of destructive-proliferative vasculitis, damage to the coronary arteries (CA) and other visceral arteries manifested by fever, changes in the mucous membranes, skin, and lymph nodes. The initial KD therapy is intravenous immunoglobulin (IVIG) at a dose of 2 g/kg coupled with acetylsalicylic acid. However, 10% to 38% may be resistant to standard therapy. There are no uniform recommendations for the management of patients with immunoglobulin-resistant KD. Possible therapies include repeated IVIG, high-dose glucocorticoids, genetically engineered biological drugs and other cytostatic drugs. Authors represent a clinical case of a 4-month-old boy with a complete form of KD, giant CA aneurysms and a resistance to the previous 4 courses of immunomodulatory therapy (2 courses of IVIG, etanercept, pulse therapy with methylprednisolone) with the effective use of the tumor necrosis factor alpha blocker, infliximab.
METHOTREXATE INTOLERANCE IN CHILDREN WITH JUVENILE IDIOPATHIC ARTHRITIS ACCORDING TO THE METHOTREXATE INTOLERANCE SEVERITY SCORE (MISS) QUESTIONNAIRE: A SINGLE-STAGE STUDY
Authors:   Bashkir State Medical University, Ufa, Republic of Bashkortostan, Russia, Zhukov S.S. ,   Bashkir Republican Children’s Clinical Hospital, Ufa, Republic of Bashkortostan, Russia, Malievskiy V.A. ,   Bashkir State Medical University, Ufa, Republic of Bashkortostan, Russia
Published: October 2023

Juvenile idiopathic arthritis (JIA) is the most common rheumatic disease in childhood. First-line therapy is the prescription of Methotrexate (MTX) though this drug can cause undesirable effects which in its turn dictates the need for the use of diagnostic techniques that would allow early detection of intolerance to MTX. One of such diagnostic approaches is the Methotrexate Intolerance Severity Score (MISS) questionnaire. The purpose of this research was to evaluate the frequency of MTX intolerance in children with JIA using the Russian-language adaptation of the MISS questionnaire. Materials and methods used: a single-center, single-stage study of children aged 3 to 17 y/o with a non-systemic variant of JIA who were prescribed MTX was conducted using the 2011 MISS questionnaire in Russian. The MTX intolerance was determined if the patient scored 6 points and above. Results: 250 patients (78 boys and 172 girls) were included in the study. MTX intolerance using the MISS questionnaire was identified in 30% of patients; the most common complaint was MTX-associated nausea. The cut-off point for the questionnaire was estimated using the ROC analysis. The area under the ROC curve was 0.945. Patients scoring 6 points with a sensitivity of 94% (95% CI 78-97) and specificity of 100% (95% CI 80-100) were intolerant to MTX. The validity of using the questionnaire to identify individuals with MTX intolerance has been demonstrated therefore the questionnaire can be recommended for wider use. Conclusion: MTX intolerance, which was determined by the total score (6 points and above) was identified in 75 patients on MTX therapy.
Properties and Application of Electrochemically Anodized Ta2O5 Nanostructures: A Review
Authors: Abdul Rani Rozina
Published: October 2023

Anodization is one of the simplest synthesis methods that can be employed to generate generous nanostructures metal oxide. Knowing the potential of anodized Tantalum Pentoxide (Ta2O5) to form the desired nanostructure which is capable to produce outstanding performance, the elements and factors influence properties enhancement were gathered. The effect of parameter variation during anodization such as electrolyte composition, voltage variation, and anodization duration was evaluated to inspect the nanostructure formed. The results generated the differences in properties of nanostructures. Characterization methods such as field emission scanning electron microscopy (FESEM), X-ray diffraction (XRD), Transmission electron microscopy (TEM), Atomic force microscopy (AFM), and X-ray electron spectroscopy (XPS) were used to investigate the structural, electrical, chemical, optical, biological and mechanical properties of anodized Ta2O5. The findings show that anodized Ta2O5 is reliable to be employed as gas sensor, photocatalysis, pH sensor, biomedical materials and humidity sensor due to its superior properties to produce high sensitivity device and increase the efficiency. In this review, a general overview of anodized Ta2O5 is presented which focuses on its fundamental properties, method of synthesis anodized Ta2O5, anodizationparameter optimization, and recent applications in chemical and biological area, along with a discussion on future research directions relevant to this material. It is hoped that by synthesising nanostructures via anodization, the sensing performance will improve and Ta2O5 will be proven as a trustworthy metal oxide material for sensing applications.
Stress Interaction Behaviour in Alveolar Cortical Bone Fracture
Authors: Md Zain Noor Alia
Published: October 2023

Improving the mechanical integrity of the dental implantation through optimal stress distribution between the implant and the surrounding bone has reduced the risk of bone injury and implant loosening risk. Inversely, the clinical failure of implantation will result in the formation of microcracks in the alveolar bone. The uncertainty of stress interaction intensity between microcracks has been an unsolved issue regarding the load transfer between the implant and alveolar bone. This study investigates the magnitude of stress shielding and stress amplification to explain the behaviour of double edge (DE) microcracks that are identically formed due to various stability conditions of implantation under occlusal loading. A series of finite element modelling have been conducted to simulate the stress shielding and stress amplification behaviour based on the displacement extrapolation method (DEM) and contour integral analysis. The occlusal loading schemes are translated into Mode I, Mode II and Mixed-mode loading. The presented DE models have demonstrated the transition behaviour of DE parallel microcracks into a single edge (SE) crack basic behaviour, where the crack unification limit (CUL) and crack interaction limit (CIL) are identified at lower and a higher rates of a/W. The occlusal loading has shown significant influence on the intensity of stress shielding and stress amplification behaviour in a form of DE-SE microcracks interaction for Mode I and Mixed-mode occlusal loading.
Enhancement of Mechanical Properties and Corrosion Resistance of Cast Iron Alloy Using CO2 Laser Surface Treatment
Authors: K. Fayyadh Sameer
Published: October 2023

This work aimed to study the effect of laser surface treatment on the mechanical characteristics and corrosion behaviour of grey cast iron type A159. Many technical applications used conventional surface treatment, but laser surface hardening has recently been used to enhance the surface properties of many alloys. The mechanical characteristics, including microstructure, microhardness, and wear resistance of A159 grey cast iron, were studied, in addition to corrosion behaviour. The experimental laser parameters in this work were 0.9, 1.2, and 1.5 KW power with continuous wave carbon dioxide lasers with scanning speeds of 10 and 12 mm/s were used. The results found that phase-transitional alterations in microstructure were influenced by laser therapy. Also, the microhardness increased with increasing power, with the maximum reaching approximately 950 HV while the base metal has an average of approximately 260 HV. Also, we found the power laser increased corrosion resistance by lowering the corrosion rate (CR) from 21.10 for the untreated sample to 1.02 (m.p.y.), additionally, corrosion protection efficiency (CPE) increased to 95.27 percent. On the other hand, the wear test revealed that mass loss decreased as laser surface treatment power increased; it reached 0.19 g for the laser-treated samples, compared to 1.25 g for the base metal after the 50th minute of the wear experiment.