bluuebunny/crossref_metadata_2025 huggingface dataset:
Breast elastography: diagnostic performance of computer-aided diagnosis software and interobserver agreement
Authors: Fleury Eduardo F. C. , Marcomini Karem
Published: January 2020

Abstract Objective: To determine the best cutoff value for classifying breast masses by ultrasound elastography, using dedicated software for strain elastography, and to determine the level of interobserver agreement. Materials and Methods: We enrolled 83 patients with 83 breast masses identified on ultrasound and referred for biopsy. After B-mode ultrasound examination, the lesions were manually segmented by three radiologists with varying degrees of experience in breast imaging, designated reader 1 (R1, with 15 years), reader 2 (R2, with 2 years), and reader 3 (R3, with 8 years). Elastography was performed automatically on the best image with computer-aided diagnosis (CAD) software. Cutoff values of 70%, 75%, 80%, and 90% of hard areas were applied for determining the performance of the CAD software. The best cutoff value for the most experienced radiologists was then compared with the visual assessment. Interobserver agreement for the best cutoff value was determined, as were the interclass correlation coefficient and concordance among the radiologists for the areas segmented. Results: The best cutoff value of the proportion of hard area within a breast mass, for experienced radiologists, was found to be 75%. At a cutoff value of 75%, the interobserver agreement was excellent between R1 and R2, as well as between R1 and R3, and good between R2 and R3. The interclass concordance coefficient among the three radiologists was 0.950. When assessing the segmented areas by size, we found that the level of agreement was higher among the more experienced radiologists. Conclusion: The best cutoff value for a quantitative CAD system to classify breast masses was 75%.
Uses of wild vertebrates in traditional medicine by farmers in the region surrounding the Serra do Conduru State Park (Bahia, Brazil)
Authors: Teixeira Joanison Vicente dos Santos , Santos Jade Silva dos , Guanaes Deyna Hulda Arêas , Rocha Wesley Duarte da , Schiavetti Alexandre
Published: January 2020

Abstract: Wild and domestic animals and their by-products are important ingredients in the preparation of medicines traditionally used in folk medicine, present in various human cultures since antiquity. However, the decline in the number of species in neotropical regions as a result of hunting for various purposes, including food, medicine and magico-religious use, has placed some species - especially endemic species - at risk of extinction. In this context, the present study aimed to identify the wild vertebrate species used in folk medicine in five communities in the region surrounding the Serra do Conduru State Park (PESC), Bahia, Brazil. Forty-five hunter-farmers were interviewed, citing 23 species, from which 17 raw materials are extracted for prevention and/or treatment of 19 illnesses. Mammals were the most cited taxon followed by birds and reptiles. Among the species mentioned, Cuniculus paca is the most used for zootherapy purposes, followed by Salvator merianae and Sphiggurus insidiosus. There was dissimilarity between the communities in relation to the diversity of species used for zootherapy. Ten categories of body systems were classified for which the therapeutic resources are recommended. Disorders related to the middle and inner ear were the most cited. Some of the species mentioned are endangered, such as Bradypus torquatus and Lachesis muta. This research demonstrated that zootherapy is a traditional practice embedded in these communities. Further studies are needed to broaden knowledge of other species that may have important cultural value for these families, as well as to evaluate the potential implications of the uncontrolled use of these species in traditional medicine in an ecological context, since the practice of zootherapy can excerpt pressure on critical animal populations and threaten biodiversity.
Antimicrobial activity of propolis extract fractions against Staphylococcus spp. isolated from goat mastitis
Authors: Santos Heidy C. Dos , Vieira Dielson S. , Yamamoto Sandra M. , Costa Mateus M. , Sá Maria C.A. , Silva Eva M.S. , Silva Tania M.S.
Published: January 2020

ABSTRACT: The indiscriminate use of antibiotics in the treatment of caprine mastitis causes the appearance of resistant microorganisms, besides leaving residues in milk, putting at risk to human health. In this way, propolis is an alternative in the treatment of diseases because it has antimicrobial activity, mainly because of the presence of flavonoids in its composition. The aim of this study was to evaluate the antimicrobial potential of propolis to Staphylococcus spp. Isolated from cases of goat mastitis and qualify the crude ethanoic extract by high performance liquid chromatography (HPLC). In this study, the minimum bactericidal concentration values of propolis extracts in ethanol, ethyl acetate and hexane showed that the best concentrations capable of promoting the highest mortality of the isolates of Staphylococcus spp. from mastitis in goats, were 6250, 3125 and 1562.5μg/mL, respectively. By the microplate adherence test, it was found that 20.78% isolates were not able to form biofilm, 14.70% were classified as moderate and 64.70% were weak and none as a strong biofilm producer. Propolis in its different diluents was able to affect the formation of biofilm and showed a pronounced marked antimicrobial activity against Staphylococcus spp. strains and may be indicated for use in in vivo studies.
Poisoning by Brachiaria spp. in various lamb breeds at increasing levels of supplementation during growth
Authors: Melo Gleice K.A. , Ítavo Camila C.B.F. , Silva Jonilson A. , Ferelli Kedma L.S.M. , Silva Pâmila C.G. , Pupin Rayane C. , Lemos Ricardo A.A.
Published: January 2020

ABSTRACT: The study evaluate the frequency of poisoning by Brachiaria spp. at the rearing, growth and termination stages in various lamb breeds at increasing supplementation levels. Forty-five lambs were used in the growth phase in pastures of Brachiaria spp. with a history of having induced poisoning. The lambs were distributed in nutritional treatments: lambs receiving mineral supplementation (MS), energy/protein supplementation (EPS) at 0.8% of body weight (bw), EPS at 1.6% bw and EPS at 2.4% bw. The lambs were allotted two flocks (F1 and F2) of 21 and 24 lambs each. Clinical signs of poisoning were observed in all treatments. All MS lambs died. The frequency of poisoning were highest in the 0.8% EPS and 1.6% EPS treatments. All lambs in the 2.4% EPS treatment recovered. F1 lambs had a higher frequency of poisoning than F2 lambs regardless of nutritional treatment. Morbidity rates for the F1 and F2 lambs were 52.3 and 16.7%, respectively. Supplementation was not sufficient to decrease the frequency of poisoning in lambs at the termination stage, which was dependent on the genetic origin of the lambs. EPS of 2.4% bw treatment, was an efficient nutritional strategy to minimize the effects of poisoning in lambs fed on Brachiaria spp.
Initial reading and writing skills in childhood education: achievement sample in the Northeast of Brazil for obtaining specific regional performance standards
Authors: Amorim Américo Nobre Gonçalves Ferreira , Dias Natália Martins , Albuquerque Emilia Xavier da Silva , Silva Vanessa Cristina da , Falcão Amanda Christina Gomes Pereira , Guerra Vera Gabrielly Rangel , Silva Maíra Hermínio da , Santos Larissa Laís dos
Published: January 2020

ABSTRACT Purpose: the study aims to obtain preliminary normative data for early reading and writing skills of 5-year-old children in a sample from the Northeast of Brazil. It also aims to investigate the effects of the type of school (public vs. private) and the time of assessment (beginning vs. end of the school year), and whether there were significant differences in performance, as compared to those of children from the Southeast of Brazil. Methods: 389 5-year-old children from 17 private and 12 public schools were assessed in the beginning and at the end of the school year, by using the Reading and Writing Test. Each student was individually assessed in the two times of the year. Appropriate statistical tests were applied, adopting a significance level lower than 0.05. Results: the progress in the performance of private school children was stronger than that of their peers from public schools, accentuating the existing learning gap. The comparison with normative data from the Southeast revealed that the public schools in the Northeast outperformed those in all topics of comparison. Private schools in the Southeast had a better performance at the beginning of the year, but were outperformed by those of the Northeast at the end of the year. Conclusion: the differences in performance identified in the samples suggest the need for specific norms by geographical regions of Brazil, and by type of school (public or private). The data presented in this study are preliminary and can be enlarged in future studies.
Comparison of nasal geometry among adults with obstructive sleep apnea: a preliminary study
Authors: Rocha Jackson Ítalo Tavares da , Lima Anna Myrna Jaguaribe de , Silva Hilton Justino da , Gomes Adriana de Oliveira Camargo , Vitorino Paulo Augusto , Clímaco Danielle Cristina Silva , Cunha Daniele Andrade da
Published: January 2020

ABSTRACT Purpose: to compare nasal geometry between two groups of patients with different degrees of obstructive sleep apnea and to correlate apnea-hypopnea index, apnea severity and degree of daytime sleepiness with nasal areas and volume. Methods: a total of 20 adults (15 women and 5 men, mean age of 52.0±11.4 years old) without nasal obstruction were submitted to polysomnography. The subjects were divided into two groups: a) 10 individuals without apnea or with mild-grade apnea; b) 10 with moderate or severe apnea. Nasal geometry was evaluated by acoustic rhinometry. The volume, comprising the distance from the nasal valve to the posterior part of the middle nasal turbinate, and the three sectional areas corresponding to nasal valve, anterior part of the inferior nasal turbinate and posterior part of the inferior nasal turbinate, were considered. The Shapiro-Wilk, Mann-Whitney, Student’s t tests for independent samples and Spearman’s correlation coefficient were used for the analysis, with a significance level lower than 5%. Results: group 2 presented lower values in the area corresponding to the nasal valve (on the right), and higher values in the nasal turbinate areas. There was no correlation between the drowsiness scale and nasal areas and volumes. Conclusion: the area of the nasal valve was unilaterally smaller in the group with moderate and severe apnea. There was no correlation between volumes and nasal areas and excessive daytime sleepiness.
Ultrasonography of tongue movements for the /l/ sound and characterization by gender in children with typical and atypical speech development
Authors: Barberena Luciana da Silva , Rosado Isadora Mayer , Moraes Denis Altieri de Oliveira , Berti Larissa Cristina , Keske-Soares Márcia
Published: January 2020

ABSTRACT Objective: to compare the articulatory gestures of the /l/ sound, characterized by gender variable, of children with typical and atypical speech development. Methods: the sample was composed of 60 children, 30 with typical speech development and 30 with atypical speech development, aged between 4 years and 8 years and 11 months, of both genders, being the /l/ sound acquired for all children. The articulatory data (ultrasound image of tongue movement) were collected from the recording of tri/polysyllabic words with the sound /l/, considering the maximum elevation of the tongue point analyzed through the Articulate Assistant Advanced (AAA) software. The mean tongue contours of typical and atypical children were compared to the gender variable in order to observe possible differences between these groups. Results: there was a significant difference in the tongue gestures of typical and atypical children in the male gender. In females, there was less differentiation of the means of the tongue contours between the typical and atypical children. Conclusion: the group of atypical male children presented less ability to refine the tongue gestures when compared to the typical ones of the same gender.
Surface electromyography in orofacial and cervical musculature in mouth breathing children: an integrative literature review
Authors: Batista Daniella Priscila Ferracioli , Bagarollo Maria Fernanda
Published: January 2020

ABSTRACT Purpose: to review, in an integrative manner, studies using surface electromyography in the orofacial and cervical musculature in mouth breathing children aged from three to 11 years and 11 months old. Methods: the survey was conducted in national and international databases, from 1998 to 2018, in Portuguese, English and Spanish. Review articles, dissertations, book chapters, case studies and editorials were excluded. Results: 86 articles were found, 14 of which met the inclusion criteria. Most of these studies used surface electromyography to assess and describe the muscle condition of the mouth breathing population. Only one study addressed the influence of myofunctional speech therapy and two studies included physical therapy treatment, using electromyographic evaluation before and after the intervention. Given the main categories of analysis, the discussion was based on the year, state of publication and journal, sample size, scientific methodology, muscles assessed, assessment protocols used and the results of the publications. Conclusions: surface electromyography has been used mainly in the initial assessment of orofacial and postural myofunctional changes caused by mouth breathing and not as a therapeutic biofeedback, thus, it is important to conduct longitudinal studies using this instrument in mouth breathers.
Conhecimento sobre ética médica e resolução de conflitos na graduação
Authors: Graças Victor Bruno Andrade das , Souza Júnior Joilson Francisco de , Santos Jorge Gabriel Mendes Silva , Almeida Mariana Fontes Andrade , Oliveira Edvaldo Victor Gois , Santos Nila Vitória Mendes Oliveira , Medeiros Luiz Eduardo Dantas Cerqueira , Mattos Roberta Machado Pimentel Rebello de , Pimentel Déborah Mônica Machado
Published: January 2020

Resumo Estudo quantitativo transversal descritivo que tem o objetivo de avaliar a percepção do graduando em medicina sobre a importância do ensino da ética médica e mensurar seu conhecimento sobre a temática em universidade pública do Nordeste brasileiro. Por meio de questionário aplicado a 230 estudantes foi possível avaliar deficiências provocadas pela ausência do ensino formal da ética médica e discutir a necessidade de abordagens diversificadas do tema durante a graduação. Resultados mostram maior taxa de acertos entre graduandos que cursaram ao menos uma disciplina sobre ética médica, mas índice insatisfatório em ambos os grupos. Um terço dos discentes que não tiveram contato com a temática revelaram não se sentir prejudicados por essa lacuna e 25,6% da amostra sequer valorizou a importância do tema em relação a outras disciplinas da graduação. Assim, torna-se necessário rever as estratégias do ensino médico para garantir melhores profissionais no futuro.
Comunicação em cuidados paliativos: equipe, paciente e família
Authors: Campos Vanessa Ferreira , Silva Jhonata Matos da , Silva Josimário João da
Published: January 2020

Resumo Cuidados paliativos visam acolher o paciente e sua família de forma integral em casos de impossibilidade de cura da doença, valendo-se de boa comunicação para melhorar a qualidade de vida. Este estudo objetivou avaliar a comunicação na assistência paliativa e sua influência na relação entre equipe, paciente e família. Trata-se de pesquisa qualitativa, descritiva e exploratória envolvendo seis participantes abordados em instituição hospitalar de saúde pública da cidade de Suzano, no estado de São Paulo. Dados foram coletados em entrevistas semiestruturadas e avaliados com a técnica de análise de conteúdo. Conclui-se que o diálogo adequado é estratégia relevante para estabelecer boa relação entre as três partes, sendo, no entanto, necessário identificar outros fenômenos que estão além das habilidades comunicativas dos profissionais. Na perspectiva da bioética, a comunicação se destaca na assistência e cria vínculo que possibilita decisões compartilhadas.
A recepção de Nietzsche na Primeira Escola de Formação Pastoral da Igreja Evangélica de Confissão Luterana no Brasil
Authors: Feiler Adilson Felicio
Published: January 2020

Resumo Como rebento de uma família de tradição luterana, Nietzsche não poderia estar ausente do rico material produzido nos quase cem anos da presença da Escola Superior de Teologia (EST). Mesmo que o acervo bibliográfico da dita Escola esteja eminentemente voltado ao atendimento do curso de teologia, há um acervo filosófico digno de nota. Entre os diversos volumes que preenchem as dezenas de estantes da filosofia, se encontram textos escritos por Nietzsche, bem como livros escritos sobre este autor. A maioria destes escritos em língua alemã na Alemanha, mas também inúmeros escritos em alemão, porém no Brasil. Neste artigo pretendemos analisar estes últimos escritos, de maneira a realizar uma leitura de como foi a recepção de Nietzsche na primeira escola de formação de pastores do Brasil.
Ceticismo no jovem Nietzsche: das sugestões de Lange ao ensaio Sobre verdade e mentira em sentido extramoral
Authors: Campioni Giuliano
Published: January 2020

Resumo: O ensaio Sobre verdade e mentira em sentido extramoral é um texto impressionante cético, que afasta Nietzsche não apenas da precedente “metafísica da arte” de O Nascimento da tragédia, mas também nega o próprio conceito de verdade. A influência de Friedrich Albert Lange e de sua História do materialismo é importante no percurso que levará, a partir das críticas da metafísica de Schopenhauer, às posições defendidas em Sobre verdade e mentira em sentido extramoral.
A concepção nietzschiana de ceticismo em Schopenhauer como educador
Authors: Serini Lorenzo
Published: January 2020

Resumo: O objetivo do presente ensaio consiste em esclarecer a concepção nietzschiana de ceticismo presente em Schopenhauer como educador - em especial, à luz do §3 da aludida obra. Sem passar ao largo das principais preocupações de Nietzsche em sua filosofia de juventude como um todo, bem como do horizonte hermenêutico pós-kantiano que lhe é contemporâneo, o texto conta enfatizar que, na terceira Consideração extemporânea, Nietzsche está sobretudo preocupado com as consequências corrosivas do ceticismo à filosofia (e aos filósofos), e, potencialmente, à inteira cultura de sua época, razão pela qual estaria empenhado, já, na elaboração de uma sabedoria capaz de neutralizar tal periculosidade, fornecendo uma orientação aos nossos mais profundos e efetivos problemas vitais.
Alfred Fouillée, ‘leitor lido’ de Nietzsche
Authors: Fornari Maria Cristina
Published: January 2020

Resumo: Este artigo visa a investigar as críticas que o sociólogo francês Alfred Fouillé faz a Nietzsche acerca de suas concepções morais. Apoiado nos textos de seu enteado, Jean-Marie Guyau, Fouillée contrapõe uma moral do altruísmo ao que entende ser uma moral nietzschiana: individualismo, egoísmo e violência. O texto indica os equívocos da leitura de Fouillée a partir dos próprios comentários de Nietzsche ao sociólogo francês e faz algumas aproximações entre Nietzsche e Guyau.
How civil and structural engineers can help to deliver the UN’s new urban agenda
Authors: Lyons Kevin
Published: January 2020

World Cities Day last October focused on how urbanisation can help achieve sustainable development and deliver the United Nations’ ‘new urban agenda’. Kevin Lyons of UK engineering consultancy Lyons O’Neill says there is a major role here for civil and structural engineers.
The future is already here – civil engineering at the cutting edge
Authors: Sheffield Paul
Published: January 2020

This is the inaugural address of Paul Sheffield, who became 155th President of the Institution of Civil Engineers on 12 November 2019.
Eudiometry (s. XVIII analysis of the percentage of O2 in the atmosphere) v1
Authors: Grau Josep , Bonet Josep , Ferre Jordi
Published: January 2020

Reproduction of a XVIII century procedure for the analysis of the volumetric percentage of Oxygen in the atmosphere. The procedure uses polysulfides as an oxygen-consuming reactive. The change in volume of a sample of atmospheric air is measured before and after oxygen has been consumed.
Simulating colonic tissue mechanics using a structure-based material model in Abaqus v1
Authors: Patel Bhavesh
Published: January 2020

The structure-based material constitutive model typically used for the colon tissue (DOI:10.1016/j.jmbbm.2017.08.031, DOI:10.1016/j.jmbbm.2013.02.016) is not readily available in the Finite Element software Abaqus, which is commonly used for biomechanical simuations. In this protocol, we provide step-by-step guidelines to use such material model in Abaqus using the User Subroutine implemented by the autor.
Elaboration of Balance-Optimization in Economic and Mathematical Model of Development of a Large Municipal Unit: Real Experience
Authors: Novoselov Alexander S. , Kovalev Alexey E. , Gaiduk Egor A. , Mkrtchyan Gagik M.
Published: January 2020

The objective of the study is to develop a balance-optimizing economic and mathematical model which enables predicting steady and sustainable development of a large municipal unit. Using the method of dynamic programming introduced by Richard Bellman, the authors worked out the economic and mathematical model for optimizing the key indicators of soсial and economic development of a municipal unit. The model used and predicted indicators included in the list of the key performance indicators of municipal unit authorities. There is an analysis of the results of applying the model for a large municipal unit — Novosibirsk. The calculations made by the authors indicate that the model may work with actual economic information and may be used for predicting and making managerial decisions at a municipal level
Social Tension Factors: Estimation and Analysis Issues (Case Study: the City of Omsk)
Authors: Kapoguzov Evgeny A. , Chupin Roman I. , Kharlamova Maria S.
Published: January 2020

The study describes the problems of social tension factors measurement and estimation in cities and its current state in Omsk. The empirical basis of the study is the sociological survey data, conducted by the Omsk Regional Center of Public Relations and the Sociology Department of Dostoevsky Omsk State University. 975 people from 5 urban districts of Omsk were interviewed during the survey. Data analysis was carried out using frequency analysis methods and contingency tables. The significance and essentiality of the differences were estimated using the chi-square and Cramer’s V criteria. Age and education turn out to have the most significant impact on respondents’ opinions; people with secondary or higher education are more often dissatisfied with the situation in the region, as for the age criterion, the group from 30 to 44 is the most dissatisfied one. The ranking of problems by importance from the respondents’ point of view was done on the basis of frequency analysis. The leading positions are occupied by the social and economic problems such as low salaries, consumer goods prices, infrastructure of the city and public utilities, as well as bureaucracy of local authorities. Judging by the protest potential of Omsk citizens, it was concluded that the population is dissatisfied with the work of the local government. However, the protest potential is estimated as low, which is partially explained by the growing negative migration balance. As a result, recommendations on improving monitoring and analysis of social tension factors in the city have been offered
Uma Análise Crítica sobre os Ajustes Adicionais Considerados nas Divulgações da Medida não-GAAP “EBITDA Ajustado” em Relatórios de Companhias Listadas Brasileiras
Authors: Vasconcelos de Andrade Gabriela , Dal-Ri Murcia Fernando
Published: January 2020

Objetivo: Esta pesquisa busca identificar quais são os tipos de ajustes adicionais com maior magnitude realizados via divulgações da medida não-GAAP “EBITDA Ajustado” das maiores companhias listadas brasileiras e realizar uma análise sobre a adequação de tais ajustes sob uma perspectiva crítica de suas naturezas.

Método: Foram investigados em press releases de companhias do índice IBrX 100 quais os ajustes adicionais com maior magnitude realizados pelas companhias da amostra e em seguida realizada uma análise crítica sobre a possível utilidade ou oportunismo destes ajustes sob a ótica da teoria da regulação e de premissas da assimetria informacional. Os períodos abrangidos pela pesquisa foram os períodos trimestrais de 2014 e 2015.

Resultados: Os tipos de ajustes com maior magnitude são Impairment (83%), Correção de erros (4%), Equivalência patrimonial (1%), Dividendos recebidos (1%) e Provisões (1%), bem como que 76% dos ajustes efetuados são consequência de princípios e regras contábeis.

Contribuições: As evidências do presente estudo corroboram com a posição do IASB sobre a importância de medidas não-GAAP, atualmente discutidas pelo referido órgão em ações com o intuito de melhorar o reporte financeiro, incluindo o uso de informações não-GAAP em peças contábeis. Os resultados enriquecem o debate sobre o tema no Brasil.
TERMINOLOGY OF FRENCH LINGUISTICS AND LINGUISTIC SYNERGETICS
Authors:   Ternopil Volodymyr Hnatiuk National Pedagogical University, Ukraine, Kosovych Olga
Published: January 2020

In the article on the base of the linguistic synergetics concept of G. G. Piotrovsky the problems of French linguistics metalanguage, issues of linguistic terminology are examined. The author emphasizes that the metalanguage of linguistics is a complex phenomenon, which, on the one hand, there are the system relations between terms, on the other one there are general academic vocabulary, words and phrases that are used when describing various aspects of linguistic research. Terminology of linguistics requires a special effort in the studying, because the object-language and metalanguage coincide in terms of expression, that is, have the same substance. The article presents the analysis of the metalanguage state of French linguistics, which is a diachronic interweaving of numerous schools and directions, author’s theories and concepts; the distinctive features of the French linguistic terminology are examined. It is noted that in the semiotic aspect the French linguistic terminology is characterized by the following properties: French linguistic term is a simple or complex sign that in the framework of French linguistics embodies a linguistic concept in its meaning. Terminological field of French linguistics meets the semantic space that is a counterpart of the French linguistics as a special subject area and includes the totality of semantic fields of general linguistic, grammatical, phonetic, phonological and lexicological terms.
SAÇ DÖKÜLMESİ: LABORATUAR İNCELEMELERİ KİME GEREKLİ?
Authors: Aktaş Habibullah , Ertuğrul Gökşen
Published: January 2020

AMAÇ: Bu çalışmanın amacı saç dökülmesi şikâyetiyle başvuran hastalarda öykü ve fizik muayenenin önemini vurgulamak, hangi hastalarda laboratuvar tetkilerinin gerekli olduğunu ortaya koymaktır.GEREÇ VE YÖNTEM: Çalışmaya Karabük Eğitim ve Araştırma Hastanesi Dermatoloji Polikliniğine Nisan 2017-Nisan 2018 tarihleri arasında saç dökülmesi şikayeti ile başvuran 622 hasta dâhil edildi. Hastane veri tabanındaki elektronik dosyalar yardımıyla herhangi bir saç dökülme türüne ait tanı alan hastaların tanı ve tedavi süreci içinde istenen tam kan sayımı, serum glukoz, vitamin B12, vitamin D, TSH, serum demir, demir bağlama kapasitesi sonuçları, eşlik eden hastalıkları kaydedildi. Bu veriler hastaların demografik özellikleriyle ve literatürle karşılaştırıldı.BULGULAR: 622 hastanın 339’u (%55) kadın, 283’ünü (%45) erkek idi. Saç dökülmesi yakınmasıyla başvuran hastaların 321’ini (%51) yaygın saç dökülmesi, 210’unu (%33) alopesi areata, 72’sini (%12) androgenetik alopesi tanısı alan hastalar oluşturdu. Skarla sonuçlanmış saç kaybı yakınması olan hasta sayısı 14, saç dökülmesi yakınması nedeniyle başvurup tinea capitis tanısı alan hasta sayısı da 5 olarak belirlendi. Yaygın saç dökülmesi yakınmasıyla başvuran kadın hastaların %10’unda demir eksikliği anemisi, %30’unda Vitamin D eksikliği saptandı. Yaygın dökülme yakınması olan kadın hastaların %10’unda görülen demir eksikliği dışında, alopesi areata, androgenetik alopesi ve skatrisyel alopesili kadın hastalarda anormal labaratuar bulgusu saptanmadı. Saç dökülmesi ile başvuran tüm erkek hastalarda da saç dökülmesiyle ilişkilendirilebilecek anormal labaratuar bulgusu saptanmadı.SONUÇ: Sonuç olarak saç dökülmesi şikâyeti ile başvuran bazı hastalarda laboratuar tetkikleri, saç dökülmesinin nedeni hakkında fikir vermektedir. İyi bir anamnez ve fizik muayene hangi hastada hangi testlerin istenmesi gerektiği konusunda yol gösterici olabilmektedir.
SYNTACTIC CHARACTERISTICS OF ADVERTISING DISCOURSE
Authors: Malyuga E. N.
Published: January 2020

The article highlights three key syntactic characteristics of advertising discourse, analyzed on the basis of English-language advertising texts of non-specific thematic affiliation: the predominance of a certain type of sentences, commitment towards syntactic compression and a specific composition of arguments, as well as the inherent use of syntactic rhetorical techniques. The specifics of the syntactic design of advertising texts is studied using structural, stylistic and pragmatic methods of analysis with the aim of describing the compositional syntactic construction of advertising messages and characterizing the corresponding peculiarities of the way advertising information is being perceived by a potential consumer. The findings of the study summarize the set of syntactic characteristics of advertising text design: 1) the success of the advertising discourse depends not only on the correct selection of words, but also on the syntactic organization of the advertising text; 2) although all types of sentences are present in the English-language advertising discourse, imperative sentences are the most common and pragmatically effective; 3) an advertising message is better perceived and memorized when it is constructed as a short text subject to syntactic compression; 4) advertising text efficiency depends on the positioning of the arguments in its syntactic structure, and the most effective model is where the key argument is located in the heading, the evidence argument is placed in the main text, and the generalizing argument is exposed in the echo phrase; 5) syntactic rhetorical tropes are an important advertising tool, since they are more memorable and can attract the attention of a potential consumer, adding an element of surprise and creating a more positive attitude towards the product as a whole; 6) English advertising texts typically contain such syntactic tropes as ellipsis, parallel constructions, inversion, parcellation, antimetabole, and rhetorical questions.
STYLE AND INTERTEXTUALITY OF H.H. MUNRO’S NOVEL «THE UNBEARABLE BASSINGTON» (1912) IN THE CONTEXT OF THE EDWARDIAN EPOCH
Authors: Safonova M. A.
Published: January 2020

The article probes the stylistic and intertextual features of H.H. Munros (Sakis) novel The Unbearable Bassington (1912), which has not yet been considered from the linguistic point of view The relevance of the research is conditioned by the fact that most of his texts have not been translated into Russian, and by the writers interest in Russian history and culture, which makes his work essential in terms of intercultural communication.
The purpose of the paper is three-fold: to reveal the type of lexical connotations prevalent in the text; to analyze the means of expressive syntax used in the novel; and finally, to comment on the links the text demonstrates in relation to the social, historical and aesthetic realia of the Edwardian epoch.
The research is based on the findings of international scholars on the work of H.H. Munro and other authors of the early 20th century (A.J. Langguth, S. Byrne, G.J. Spears, B. Gibson, L.M. Birden, J.S. Salemi, V.S. Pritchett, D. Trotter), and on connotative lexis and expressive syntax (O.S. Akhmanova, O.V. Alexandrova, M.Y. Blokh, G.A. Zolotova, L.V. Polubichenko).
Among the methods applied are linguostylistic and descriptive-analytical analyses, as well as linguostylistic stratification. The following lexical items in the text were investigated: formal and French lexis, proper names, quotations from other literary sources, words semantically pertaining to the topic theatre. In terms of minor syntax, marked word combinations in deformed proverbs and sayings were analyzed. The study of major syntax was focused on compound sentences with paratactic bonds describing banal, everyday situations.
The results showed that the social connotations found in formal vocabulary and French words prevail in the novel. The less frequent literary and mythological connotations are carried by proper names and quotations. It was established that a typical syntactic trait of the text is using extended compound or complex sentences where the subject and predicate are separated from each other by parentheses containing formal lexis. The text was divided into three strata where the marked units mentioned above are present in different proportions.
The article contains parallels with the texts of O. Wilde, R. Firbank, N. Coward, V. Sackville-West, H. James, E. Waugh, J. Conrad.
The results obtained are applicable to further research in linguostylistics, functional stylistics, semantics, and translation studies.
RUSSIAN MULTI-PARTY SYSTEM IN THE NEWEST DOMESTIC HISTORIOGRAPHY
Authors: Leonov M. I.
Published: January 2020

The study of the Russian multi-party system was laid by the 1990 conference held in 1990 at the Institute of Marxism-Leninism, the most important points of it can be considered the 2003 conference at the Institute of History of the Russian Academy of Sciences in November and the international round table Russian multi-party system and Russian crises of the XXXXI centuries (Moscow, March 27, 2015). At first, the main systemic principles of a multi-party system were called integrity, structurality, hierarchy; conditionality of the development of the system by its relations with the environment, and the folding of the system of political parties was dated from the end of 1905 the beginning of 1906. It was believed that parties expressed the interests of certain social group classes and were associated with the masses. Subsequently, the researchers came to the conclusion that there were no purely class parties either in terms of their social composition or social groups and strata, whose interests were declared in programs and slogans; and a characteristic feature of the Russian multi-party system was that its creator and main character was the intelligentsia. Subsequently, a number of authors insisted on the purely intellectual essence of domestic parties, calling the Russian multi-party system a myth; most authors, noting the leading role of the intelligentsia in the organization and functioning of parties, were associated with certain masses. In general, the Russian multi-party system was significantly different from the multi-party system of developed countries.
PEDAGOGICAL CONDITIONS OF PREPARATION OF UNIVERSITY GRADUATES FOR SELF-REALIZATION IN PROFESSIONAL ACTIVITY
Authors: Melnik N. M. , Nesterenko V. M.
Published: January 2020

The article examines the problem of convertibility of human potential created in the process of obtaining higher education into human capital, ensuring high rates of innovative growth of a competitive national economy. The necessity and possibility of formation of intellectual-informational support for the co-evolution of human potential and human capital in an innovative economy are proved. It is argued that the co-evolution of human potential and human capital is ensured by the ability of a specialist to interact with a rapidly changing real professional environment in real time in order to create an innovative product. The concept of creating intellectual-informational support for the co-evolution of human potential and human capital is proposed and mathematically justified. As a result of the implementation of the developed system, the task of preparing a university graduate for self-realization in future professional activities is solved.
CONTENT OF THE PROFESSIONAL GIFTEDNESS OF A LAWYER
Authors: Khramtsov Ye. B.
Published: January 2020

The paper deals with the problem of professional activity successfulness conditioned by genetic, intellectual and emotional characteristics of an individual. Its foundation of specialists productive activity is proved relying on B.M. Teplovs point of view about giftedness as a combination of abilities unique in qualities. Internal and external conditions are distinguished as professional giftedness factors. For defining the structure of the lawyer professional giftedness the principle of the giftedness and consciousness structures correlation is applied based on the principle of the consciousness and activity unity. The attention to the quality of maintenance of the students (future lawyers) professional giftedness development process is paid. The necessity for university lecturers preparedness to the students professional giftedness development is noted. The necessity demands integration of the forms and methods of educational and non-educational activity. The sample data is justified by the legal profession difficulties that require psychophysical efforts and tension for achieving aims and emotional stability to negative facts. The attempt to clarify the meaning of professional activity of a lawyer conditioned by the determinate relation to the world, the type of existence, which defines the essence of activity, is made.
READINESS OF A UNIVERSITY PROFESSOR TO THE ORGANIZATION OF INCLUSIVE EDUCATION
Authors: Rodina L. I.
Published: January 2020

The inclusion of people with disabilities in the education process at educational institutions is a new task for the Russian educational system. The implementation of the inclusive education system at the university is based on the principle of equal and different and actualizes the concept of accessibility quality. The essence of inclusive education is expressed by teaching disabled students together with other students in accordance with general educational standards, requirements for the process, content and quality.
Nowadays, educational system faces some problems as the development of conditionals for the teaching students with disabilities. The educational process should be accessible and conducted at a high level. Creation an accessible environment is a requirement for institutions of higher education.
The article discusses theoretical and practical aspects of staffing for inclusive education: the process of inclusion is considered as an integrator to improve social and labor relations in the social context of the education development. Regulatory aspect of inclusive education and staffing system for inclusive processes are discussed in the article.
As the result, the inclusive, pedagogical and social effectiveness of measures to develop a staffing system in the inclusive education implementation are analyzed.
Efficiency of using SNP markers in the MSTN gene in the selection of the Pushkin breed chickens
Authors: Dementeva N. V. , Vakhrameev A. B. , Larkina T. A. , Mitrofanova O. V.
Published: January 2020

In the poultry industry, indicators reflecting the growth rate of young stock and the exterior characteristics of chickens are important benchmarks for breeding. Traditional selection based on phenotypic evaluation is characterized by low efficiency with a low character inheritance ratio and is difficult to apply in small groups of animals and birds bred in bioresource collections. The use of molecular genetic markers associated with economically important traits makes it possible to carry out early selection of birds. This entails an increase in the profitability of the poultry industry. Recently, single nucleotide polymorphisms (SNPs) have served as convenient markers for selection purposes. For five generations (P1–P5), an experimental selection of hens of the Pushkin breed was carried out for live weight. It was based on selection for single nucleotide polymorphism rs313744840 in the MSTN gene. As a result, a significant increase in the frequency of allele A in this gene, from 0.11 to 0.50, took place. The association of SNP markers with meat qualities in the experimental group led to changes in the exterior profile of an adult bird at 330 days of age. The individuals with the AA and AG genotypes had the greatest live weight and longest body. As a result of selection, the bird on average became larger due to an increase in the number of heterozygous individuals with long bodies and large chest girths. The depth of the chest and the width of the pelvis increased due to an increase in the frequency of allele A in the experimental population. A tendency towards an increase in these indicators with the substitution of G with A in the genotype was found. Saturation of the population with desirable alleles led to an increase in the average live weight of the chickens. Analysis of the exterior parameters of adult birds showed that this growth is achieved by increasing the depth and volume of the bird body, and not by increasing the length of the limbs. Thus, marker selection carried out for five generations in the experimental population of Pushkin breed chickens to increase body weight has reliably (p < 0.001) changed the exterior profile of adult birds.
Gas chromatography-mass spectrometry in the taxonomy of Miscanthus
Authors: Slynko N. M. , Burmakina N. V. , Potseluyev O. M. , Kapustyanchik S. Yu. , Galitsin G. Yu. , Goryachkovskaya T. N. , Kuybida L. V. , Shekhovtsov S. V. , Peltek S. E. , Shumny V. K.
Published: January 2020

Chemotaxonomy as a system approach deals with intra- and interspecific polymorphism of a group of taxa in order to clarify their taxonomic positions or to select material for selection or introduction. In this study we performed chemotaxonomic analysis of specimens of Miscanthus sinensis and M. sacchariflorus collected in the Russian Far East and of hybrid plants of both natural and artificial origin. We found 153 substances and identified 143 of them in extracts of eleven Miscanthus plants by gas chromatography-mass spectrometry (GC-MS). These substances can be grouped into alkanes (20 compounds), fatty acids (34), phenols (13), sterols (18) toсopherols (8), norterpenoids (12), and phytols (13), as well as their derivatives. The main components of the extracts of miscanthus samples are fatty acids and their derivatives (total content 19.94–41.02 %), dominated by palmitic and linolenic acids, and sterols (mainly β-sitosterol, stigmasterol, and α-amyrin), which constitute 17.15–31.73 %. The values of the CPI “oddness index” for the alkane components of the extracts were within 1.55–7.18, with extracts from leaves of the Far Eastern samples characterized by the lower half of this range (1.55–2.74), while extracts from leaves of hybrids fell to the upper half (5.78–7.18). Principal component analysis of extraction profiles allowed us to separate three distinct clusters: M. sinensis, M. sachariflorus, and their hybrids, as well as to verify the origin of one of the natural hybrids. The results of chemotaxonomic analysis mostly matched those of DNA sequencing of a fragment of the plastid genome, which, moreover, allowed us to identify the species nature of the maternal plants used to obtain these hybrids. Chemotaxonomic analysis using GC-MS was found to be an efficient additional technique to delimit various morphological forms of M. sinensis, M. sachariflorus, and their hybrids.
In silico mapping of coronary artery disease genes
Authors: Zorkoltseva I. V. , Belonogova N. M. , Svishcheva G. R. , Kirichenko A. V. , Axenovich T. I.
Published: January 2020

To date, more than 100 loci associated with coronary artery disease (CAD) have been detected in large-scale genome-wide studies. For some of the several hundreds of genes located in these loci, roles in the pathogenesis of the disease have been shown. However, the genetic mechanisms and specific genes controlling this disease are still not fully understood. This study is aimed atin silicosearch for new CAD genes. We performed a gene-based association analysis, where all polymorphic variants within a gene are analyzed simultaneously. The analysis was based on the results of the genome-wide association studies (GWAS) available from the open databases MICAD (120,575 people, 85,112 markers) and UK Biobank (337,199 people, 10,894,597 markers). We used the sumFREGAT package implementing a wide range of new methods for gene-based association analysis using summary statistics. We found 88 genes demonstrating significant gene-based associations. Forty-four of the identified genes were already known as CAD genes. Furthermore, we identified 28 additional genes in the known CAD loci. They can be considered as new candidate genes. Finally, we identified sixteen new genes (AGPAT4, ARHGEF12, BDP1, DHX58, EHBP1, FBF1, HSPB9, NPBWR2, PDLIM5, PLCB3, PLEKHM2, POU2F3, PRKD2, TMEM136, TTC29andUTP20) outside the known loci. Information about the functional role of these genes allows us to consider many of them as candidates for CAD. The 41 identified genes did not have significant GWAS signals and they were identified only due to simultaneous consideration of all variants within the gene in the framework of gene-based analysis. These results demonstrate that gene-based association analysis is a powerful tool for gene mapping. The method can utilize huge amounts of GWAS results accumulated in the world to map different traits and diseases. This type of studies is widely available, as it does not require additional material costs.
Przyroda niemożliwa? Ślady ekopoetyckie w Leśmianowskiej zieloności
Authors: Lekowska Daria
Published: January 2020

Szkic Przyroda niemożliwa? Ślady ekopoetyckie w Leśmianowskiej zieloności jest zarazem propozycją, jak i próbą odczytania twórczości autora Dziejby leśnej z perspektywy ekopoetyckiej. Interpretacji poddane zostają liryczne sposoby przedstawienia przyrody, z uwzględnieniem ich metonimicznego charakteru (zieloność) i uwikłania w proces kształtowania języka poetyckiego. Przyrodnicze uniwersum zarysowane przez Leśmiana wiąże się ze zgodą na różnorodność, skomplikowanie i nieuchwytność natury w procesie poznania, która jednocześnie w połączeniu z materią słowa obdarzona zostaje poznawczym potencjałem. Leśmianowskie wiersze zdają się tworzyć nie tyle spójny ekopoetycki projekt, co raczej przejawiać pewną ekopoetycką intuicję.
Bolesław Leśmian w rosyjskojęzycznym Internecie a kwestia popularności
Authors: Bednarczyk Anna
Published: January 2020

Celem podjętych badań było uzupełnienie wcześniejszych ustaleń różnych badaczy o zaistnieniu twórczości Bolesława Leśmiana w Rosji, a przede wszystkim w Rosji dzisiejszej, o relację dotyczącą przestrzeni Internetu. Przeprowadzona analiza dotyczyła zarówno uznanych stron internetowych, prezentujących przekłady literatury obcojęzycznej na język rosyjski, jak i wybranych stron autorskich, na których zamieszczono amatorskie tłumaczenia, a także stron, na których pojawiły się różnego rodzaju wzmianki o polskim poecie.

W artykule odniesiono się także do problematyki popularyzacji twórczości polskiego poety i wykorzystania tej twórczości jako podstawy dla własnych utworów literackich bądź wypowiedzi filozoficznych.

Zostały w nim też odnotowane zaistniałe w przestrzeni Internetu, a poświęcone Leśmianowi wiersze oraz utwory wokalne, będące rezultatem stworzenia kompozycji muzycznych do tych tekstów, co niewątpliwie jest dowodem jego popularności wśród rosyjskojęzycznych internautów.