bluuebunny/crossref_metadata_2025 huggingface dataset:
The oxidation study of N,N-diethyl-meta-toluamide in dual frequency ultrasonic reactor
Authors: Eren Zeynep , O'shea Kevin
Published: August 2020

With the increasing concern of emerging contaminants (ECs), advanced oxidation processes (AOPs) have been widely investigated to fulfill the drinking water quality because of the potential adverse health effects of ECs. Accordingly, N,N-diethyl-meta-toluamide (DEET) is selected as a model compound belonging ECs to monitor its ultrasonic oxidation which is one of the most popular AOPs in a dual frequency ultrasonic reactor (DFUR) using low-frequency probe (20 KHz) and high-frequency transducer (640 KHz) type sources. DFUR was calorimetrically optimized in terms of power densities of both ultrasonic sources in order to provide the highest sonochemical yield with efficient energy output. Pseudo-first order kinetic equation was applied to results by measuring the concentration decreasing during the oxidation reactions. The pseudo-first-order rate constants, k, increased from 7.8x10-3 min-1 (640 kHz, R2=0.930) to 13.5x10-3 min-1 (DFUR, R2=0.990), by contrast, the rate constant was only 0.7x10-3 min-1 (R2=0.281) for 20 kHz low-frequency ultrasonic source. DEET oxidation was evaluated with the presence of different gas saturation (Ar, Air, O2, and N2); addition of hydrogen peroxide (PO), persulfate (PS) and monoperoxysulfate (MPS) and PO concentration effect (molar ratio of DEET:PO; 1:1, 1:2, 1:5, 1:10 and 1:20). The DEET oxidation rate was calculated as 35.8 x10-3 min-1 (R2=0.994) in the presence of Argon gas saturation, while it was 13.5 x10-3 min-1 (R2=0.990) when no gas bubbling. Therefore, the main degradation pathway was predicted as pyrolysis taking place inside the cavitation bubble where DEET molecules can reach. On the other side, a lower degradation rate in the presence of PO, PS, and MPS than that of no additives has indicated that the bulk phase degradation pathway for some part of DEET molecules are still occurred.
PERLINDUNGAN NASAB DALAM TEORI MAQASHID SYARIAH
Authors: Achmad Beadie Busyroel Basyar
Published: August 2020

Kemaslahatan sebagai inti dari maqâshid al-syarî‘ah, memiliki peranan penting dalam pengembangan hukum Islam. Sebab hukum Islam diturunkan dengan tujuan untuk menghadirkan kemaslahatan manusia baik di dunia maupun di akhirat. Salah satu kemaslahatan yang diayomi adalah perlindungan nasab. Nasab adalah fitrah manusia, karena manusia memiliki naluri beregenerasi. Di sisi lain, manusia memiliki fitrah kepatuhan kepada Tuhan. Sehingga dua fitrah tersebut terakumulasi pada perlindungan nasab. Perlindungan nasab berkenaan dengan kuantitas di satu sisi, dan kualitas di sisi lain. Proporsional titik yang tepat dari keduanya dilihat dari lingkup realitas yang terikat. Perlindungan nasab tidak hanya pada regenerasi saja, tapi juga mencakup pada segala perantara (wasilah) yang menunjangnya, baik pada kuantitas maupun kualitas. Pun demikian, perlindungan nasab mengakomodir sisi potensi ke depan (janib al-wujud) untuk dioptimalkan, dan sisi riil terkini untuk dipertahankan (janib al-’adam).
KONSEP ‘IDDAH DENGAN MENGGUNAKAN TES KEHAMILAN PERSPEKTIF MAQASIDUS SYARI’AH
Authors: AINUR ROFIQ
Published: August 2020

‘Iddah  disyari’atkan bagi perempuan tersebut karena dalam hukum ‘Iddah  mengandung banyak kemaslahatan yang kembali kepada suami, istri, keluarga dan masyarakat. Kemaslahatan ‘Iddah  untuk melindungi dan memelihara keturunan dari ketercampuran dengan laki-laki lain yang akan dinikahi. Sebab, kesucian seorang perempuan selama masa ‘Iddah  tanpa menikah dapat diketahui dari kebebasan dan kekosongan rahimnya dari adanya janin yang ada dalam rahimnya. Perkembangan zaman, ilmu pengetahuan dan teknologi yang canggih, hasil- hasil yang dicapai oleh Ilmu Pengetahuan dan Teknologi (IPTEK) ini luar biasa. Berkat kemajuan teknologi dalam bidang kedokteran dan juga rekayasa manusia yang sangat mengagumkan, kebersihan rahim seorang perempuan dapat diketahui melalui alat tes kehamilan Tespack (Home Pregnancy Test). Tespack bekerja dengan cara mendeteksi hormon HCG (Human Chorionic Gonadotropin) yang terdapat pada urin. Dan hanya dengan menunggu beberapa menit saja rahim seorang wanita dapat diketahui apakah di dalamnya terdapat janin  atau  tidak  dengan  tanda  positif  maupun  negatif.
FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN GANGGUAN POLA TIDUR PADA PERAWAT DI INSTALASI RAWAT INAP BAGIAN D3 RSUD CIBABAT TAHUN 2014
Authors: Mauliku Novie Elvinawaty
Published: August 2020

Gangguan pola tidur merupakan suatu kondisi dimana seseorang mengalami resiko perubahan jumlah dan kualitas pola tidur yang menyebabkan ketiadanyamanan diantaranya Insomnia, Hypersomnia, Narkolepsi, Parasamnia, Suden Infant Death Syndrome. Penelitian ini bertujuan untuk mengetahui faktor-faktor yang berhubungan dengan gangguan pola tidur pada perawat di Instalasi Rawat Inap bagian D3 RSUD X.Penelitian ini menggunakan desain penelitian cross sectional. Metode pengambilan sampel dengan teknik total sampling. Yang terdiri dari variabel shift kerja, masa kerja, konsumsi kafein, penggunaan obat tidur, dan kebiasaan merokok. Pengumpulan data dilakukan dengan menggunakan kuesioner dan data dianalisis secara Univariat dan Bivariat dengan uji chi square.Hasil analisis data didapatkan sebesar 50% perawat mengalami gangguan pola tidur, dan hasil uji statistik diketahui terdapat hubungan antara shift kerja (0.022), masa kerja (0.028), dan konsumsi kafein (0.0001) dengan gangguan pola tidur. Sedangkan variabel yang tidak berhubungan yaitu penggunaan obat tidur (0.109), dan kebiasaan merokok (1.000). Disarankan agar para perawat yang memiliki gangguan pola tidur agar berperilaku hidup sehat, perawat mendahulukan mengkonsumsi makanan yang bergizi, dan pihak rumah sakit mengadakan kegiatan olah raga rutin bagi perawat minimal 30 menit dalam seminggu.
CICS Cloud–Internet Communication Security Framework for the Internet of Smart Devices
Authors: Alam Tanweer , Benaida Mohamed
Published: August 2020

The internet of smart devices is a network of intelligent
gadgets with sensors, programs, Wi-Fi and communication network connections.
These devices store the data in cloud and process data outside the device using
the proposed Cloud-Internet communication framework. These devices can
communicate with other devices using the proposed framework. However, there are many challenges for communication security
among the internet of smart
devices. The Cloud can store the device data with security, reliability,
privacy and service availability. The communication Security has been raised as
one of the most critical issues of cloud computing where resolving such an
issue would result in a constant growth in the use and popularity of cloud
computing. Our purpose of this study is to create a framework for providing the
communication security among smart devices network for the internet of things using cloud computing. Our
main contribution links a new study for providing communication security for
the internet of smart devices using the cloud-Internet framework. This study can be
helpful for communication security problem in the framework of the Internet of Things. The proposed study generates
a new framework for solving the issue of communication security among internet
of smart devices.
Blockchain and its Role in the Internet of Things (IoT)
Authors: Alam Tanweer
Published: August 2020

Blockchain (BC) in the Internet
of Things (IoT) is a novel technology that acts with decentralized,
distributed, public and real-time ledger to store transactions among IoT
nodes. A blockchain is a series of
blocks, each block is linked to its previous blocks. Every block has the cryptographic hash code, previous block hash, and its data. The transactions in BC are the
basic units that are used to transfer data between IoT nodes. The IoT nodes are
different kind of physical but smart devices with embedded sensors, actuators,
programs and able to communicate with other
IoT nodes. The role of BC in IoT is to provide a procedure to process secured
records of data through IoT nodes. BC is a secured technology that can be used
publicly and openly. IoT requires this
kind of technology to allow secure communication among IoT nodes in heterogeneous environment. The transactions in
BC could be traced and explored through anyone who are authenticated to communicate within the IoT. The BC in IoT may
help to improve the communication security. In this paper, I explored this
approach, its opportunities and
challenges.
The Role of Cloud-MANET Framework in the Internet of Things (IoT)
Authors: Alam Tanweer , Benaida Mohamed
Published: August 2020

In the next generation of computing, Mobile ad-hoc network
(MANET) will play a very important role in
the Internet of Things (IoT). The
MANET is a kind of wireless networks that are
self-organizing and auto connected in a decentralized system. Every device in
MANET can be moved freely from one location to another in any direction. They
can create a network with their
neighbors’ smart devices and forward data to another
device. The IoT-Cloud-MANET framework of smart devices is composed of IoT, cloud computing, and MANET. This framework can access and
deliver cloud services to the MANET users through their smart devices in the IoT framework where all computations, data
handling, and resource management are performed. The smart devices can move
from one location to another within the
range of the MANET network. Various
MANETs can connect to the same cloud,
they can use cloud service in a real time. For connecting the smart device of
MANET to cloud needs integration with mobile apps. My main contribution in
this research links a new methodology for providing secure communication on the internet
of smart devices using MANET Concept in 5G. The research methodology uses the
correct and efficient simulation of the desired
study and can be implemented in a framework of the Internet of Things in 5G.
Software Defined Networks: Review and Architecture
Authors: Alam Tanweer , Aljohani Mohammed
Published: August 2020

 In the fifth-generation communication
system, secured and reliable data packets will rely on the network with high
availability and low latency. The 5G network enables the dynamic control of
nodes with low latency. Ultra-reliability is one of the challenging tasks in
software-defined networks. The ultra-reliability feature is an interface
working with high availability and low latency that brings in fifth-generation
networks. The Internet of Things will work in the societies so that it required
ultra-reliability features to empower the peoples as well as machines for
collaborating with their neSoftware Defined Networksighbors. The connections
among ultra-reliability networks are extremely hard situations to keep low
packets corruption. The Software Defined Networks (SDN) will provide a platform
for measuring, controlling, monitoring and scaling the smart objects in reality
or virtually. Virtualization enables IT, specialists, to combine or separate
the considerable networking or create new programmable networking among virtual
machines. In this article, the authors are reviewed the architecture of SDN
based on virtualization under the umbrella of 5G networks.
RF and microwave photonic high bandwidth signal processing based on Kerr micro-comb sources
Authors: Moss David
Published: August 2020

Integrated Kerr micro-combs are a powerful source for generating multiple wavelength channels to achieve photonic radio frequency (RF) and microwave signal processing, particularly in the context of transversal filters. They offer competitive advantages including a compact device footprint, high versatility, large numbers of wavelengths, and wide Nyquist bands. Here, we review recent progress on Kerr micro-comb-based photonic RF and microwave high bandwidth temporal signal processing, including integral and fractional Hilbert transforms, differentiators as well as integrators. The strong potential of optical micro-combs for RF photonic applications in terms of functions and integrability is also discussed.
BIRD FLU – COUNTER-STRATEGY
Authors: Avdosieva I. K. , Kalinina O. S. , Chaikovska O. I.
Published: August 2020

The rapid growth of international cooperative ties poses a serious threat to the spread and spread of one of the few yet the most dangerous infections on the territory of Ukraine – bird flu. In addition to the economic damage caused by this disease to the poultry industry, an important aspect is the danger to human health and the potential risks of a new pandemic variant of the virus. The epizootic situation of this disease remains complex recently and cases are reported in most developed poultry countries

                The article provides analytical material on HPBF outbreaks in 2018-2019. In 2018 the HPBF was registered in 39 countries and outbreaks ranged from 1 to 110 and the highest in Taiwan were – 110, Russia – 82, Egypt – 49, Bulgaria – 29. In 2019 HPBF outbreaks were registered in 19 countries and ranged within from 1 to 107 and the highest number was in Taiwan – 107, Mexico – 35.

                At present, there is a very difficult epizootic situation in the world for flu viruses caused by the following subtypes: H5N1, H5N2, H5N3, H5N5, H5N8, H5N9.

                 During 2018 registered strains of HPBF in the countries of the world were: N5 – 22; H5N1 – 16; H5N2 – 25; H5N3 – 2; H5N5 – 0; H5N6 – 8; H5N8 – 26; H5N9 – 1. During 2019, registered strains of HSVP in the countries of the world were harboring: N5 – 1; H5N1 – 10; H5N2 – 48; H5N3 – 17; H5N5 – 3; H5N6 – 4; H5N8 – 16; H5N9 – 0 %.

                With regard to low pathogenic avian influenza (LPBF), their worldwide wide circulation in the natural reservoir has been proven to date. In 2019 the highest number of LPBF outbreaks caused by different strains was: H5N1 – 36; H7N3 – 29 and H5N2 – 22. During 2019, the reported LPBF strains in the countries were: H5 – 6; H5N1 – 34; H5N2 – 21.1; H5N5 – 0; H5N6 – 4; H5N8 – 0; H7N3 –; H7N4 – 3; H7N9 – 1; H7N5 – 2; H7N6 – 1 %.

                The use of the following antiviral medications for the prevention and treatment of LPBF revealed their high therapeutic and prophylactic significance, namely: remantadine, amizone, aminocaproic acid and made on the basis of modern nanotechnologies – Germacap. Due to the 2-time (with an interval of 7 days) use of remantadine aerosol for prevention of LPBF epizootic among ducklings, the conservation of livestock reached 93 %, whereas in control – only 37 %. When treated with remantadine, the young growth of egg crosses for therapeutic purposes resulted in a 45 % reduction in the discharge of livestock against control by reducing death and culling.
INFLUENCE OF ARSIL FEED ADDITIVE ON HEMATOLOGICAL INDICES, PRODUCTIVITY AND STRUCTURE OF INTERNAL ORGANS BROILER CHICKENS
Authors: Zhyla M. I. , Mykhalus G. M. , Maksymovych O. A. , Lapin O. V. , Mykhalyuk O. V. , Haziiev A. R.
Published: August 2020

Poultry farming using modern technologies requires the employment of veterinary preparation for the prevention of infectious diseases and also feed additives for the improvement of metabolic functions and correction of body resistance.

The article presents the results of clinical trials of feed additives in the form of an ionic solution concentrate of the biologically active nanosilicon "Arsil". The clinical study was performed on healthy ten-day-old broiler chicken, cross "Cobb-500", organized into three groups of 20 heads each: Group I received a feed additive at a dose of 0.5 ml per 1 liter of water, group II – at a dose of 1.0 ml per 1 liter of water and group III was the control group (on a regular diet, without feed additives). The use of the studied feed additive was carried out by watering with water for 30 days. Poultry of all groups were fed with identical feeds in accordance with regulatory requirements taking into account the age of the bird. The clinical condition of the bird was monitored daily, control weightings were performed once a week and blood samples were taken for laboratory tests on days 15 and 35 of the experiment. At the end of the experiment, a diagnostic slaughter of birds of all groups and a complete pathological autopsy with selection of material for histological examination were performed.

Studies have shown that the use of the feed additive "Arsil" contributed to weight gain and average daily gain, improved the feed conversion and the tendency for the growth of the concentration of hemoglobin, hematocrit and erythrocytes in broiler chicken from the experimental groups compared with the control group at the end of fattening. The structure of the internal organs of birds of all studied groups is preserved, macroscopic changes in organs and tissues are not detected. An increase in the coefficients of mass of immune-competent organs in broiler chicken fed the feed additive "Arsil" compared with the control group was found.
RELATIONSHIP BETWEEN ANIMAL PRODUCTIVITY AND CONTENT OF SOME MACRO- AND MICROELEMENTS IN DIFFERENT FRACTIONS OF COW'S BLOOD BY ASSIGNMENT OF FEED ADDITIVE GERMATZINK
Authors: Zhurenko O. V.
Published: August 2020

The high productivity of dairy cattle, while keeping the ability to adapt and ensure the basic physiological functions of the body, creates the conditions for profitable milk production and efficient animal usage. The development and implementation of selective improvement of breeds and types methods requires the study of biological features of cattle, adaptive parameters of its productive potential. The studies were conducted on the farm of Vinarivka village of Kyiv region. The types of HNA were determined by the method of food conditioned reflexes. Four experimental groups were formed by the results of the conditioned reflex study. The cows of the experimental group feed additive “Germatsink” was applicated at a dose of 10 ml/day within 30 days. Animals in the control groups (with different types of higher nervous activity) received a standard diet. The goal of the study was to determine the correlation between productivity and the content of some macro- and microelements in the serum and blood cells of cows after feed additive “Germatsink” application. Studies have shown that Germatsink application leads to changes in the relationship between productivity and the content of some minerals in the cows’ serum. However, there was weak correlation between phosphorus and calcium in the serum and average daily yield (r = 0.41; p <0.05), and significant relationship to the content of potassium, magnesium and lithium is disappear. It was found strong correlation between content of potassium, magnesium and cuprum in serum and fat content of milk of these animals.

In 30 days after Germatsink was administered, the calcium (r = -0.48; P <0.01) and Zinc (r = 0.39; P <0.05) content was related with milk yield in cows. It was noted a change in the relationship between the quality of milk and the content of some elements in the blood cells of cows. In particular, increase of relationship between content of magnesium (r = 0.52; P <0.001), zinc (r = 0.48; P <0.01), cooper (r = 0.38; P <0.05) and fat content of animal’s milk.
TURNOVER OF ANTIMICROBIAL VETERINARY MEDICINAL PRODUCTS IN UKRAINE AS A FACTOR OF THEIR RATIONAL USE IN THE TREATMENT OF INFECTIOUS DISEASES IN ANIMALS
Authors: Kosenko Yu. M. , Ostapiv N. V. , Zaruma L. E.
Published: August 2020

The procedure for manufacture, sale and rational use of antimicrobial veterinary medicinal products in veterinary medicine must comply with the national legislation, namely the Law of Ukraine “On Veterinary Medicine”. Only authorized in Ukraine veterinary medicinal products have been used in veterinary medicine as required with the recommendations stated in package leaflet, labeling and summary of the product characteristic. The article describes main principles of monitoring process sales turnover of antimicrobial veterinary medicinal products during period of study 2015-2018.

On the suggestion of the World Organization for Animal Health (OIE) at the beginning of 2016 Ukraine started collecting annual sales data (for the previous year) on antimicrobial veterinary medicinal products in food-producing and domestic animals in accordance with the Chapter 6.9. of the Terrestrial Animal Health Code, 2016; 2018.

The main goal of this study was the implementation of OIE recommendations in monitoring process by the assessment of sales patterns of antimicrobials, their influence on prudent use, in compliance with Ukrainian National Action Plan Tackling Antimicrobial Resistance, 2019. The study was conducted during four 12-month periods (from January 1 to December 31) during 2015-2018. The data in questionnaires reports were received from marketing authorization holders and distributors and collected as suggested by OIE. The specification of the amounts of the antimicrobials annual sales during 2015-2018 according route of administration and antimicrobial classes in [kg] and [%] of active ingredient were presented.

The study revealed the main high-selling classes of antimicrobials (Tetracyclines, Penicillins and Sulfonamide+Trimethoprim); the commonly used route of administration (oral ~ 90 %) and part of veterinary critically important and important antimicrobials in total sales amounts of all antimicrobial veterinary medicinal products. Macrolides occupied the main part (10,2 %) in veterinary critically important antimicrobial medicinal products; part of Aminoglycosides was ~ 4 %; Fluoroquinolones – among 2,5 - 7,14 % and part of Cephalosporins was less than 1% during all years of the study.

This study can be considered as the first step towards implementation a national monitoring system for rational and prudent use of antimicrobials in veterinary medicine.
THE INDICES OF MILK QUALITY, REPRODUCTION, BLOOD AND RUMEN LIQUID IN HIGHLY PRODUCTIVE COWS IN THE FIRST PERIOD OF LACTATION FOR FEEDING OF MIXED-LIGANDE COMPLEXES OF ZINC, MANGANESE AND COBALT
Authors: Kropyvka Yu. G. , Bomko V. S.
Published: August 2020

The article presents data on milk productivity, reproductive function and chemical composition of milk, as well as hematological parameters of blood and rumen liquid in high-yielding Holstein cows of German selection, Ukrainian black-spotted dairy and Ukrainian red-spotted dairy breeds in the first lactation period for feeding them different doses of mixed-ligand complexes of Zinc, Manganese and Cobalt.

It is established that the use of mixed-ligand complexes of Zinc, Manganese and Cobalt in the feed mixture in comparison with their sulfates has a positive effect on milk productivity and reproductive function of cows and the chemical composition of their milk, and feed costs decrease with increasing productivity.

The use of different forms and levels of Zinc, Manganese and Cobalt in the diets of experimental cows affected protein and carbohydrate-fat metabolism and the best results were obtained when using different levels of these trace elements in the feed due to their mixed-ligand complexes.

In the rumen liquid of experimental cows, the pH value increased in the alkaline direction and the difference to the control group was statistically significant. There was also a tendency to increase residual nitrogen compared to control. There was a significant difference in the reduction of ammonia nitrogen in the rumen liquid of cows of experimental groups, which indicates better use and assimilation of crude protein.

The best indicators of milk productivity, chemical composition of milk, reproductive function, blood and rumen liquid were obtained when using mixed-ligand complexes of Zinc, Manganese and Cobalt in the feed mixture when the concentration of these trace elements in 1 kg of DM was, mg: Zinc – 60.8; Manganese – 60.8; Cobalt – 0.78; Selenium – 0.3; Copper – 12 and Iodine – 1.1. This concentration of trace elements was achieved due to their mixed-ligandent complexes, copper – its sulfate, iodine – potassium iodide, selenium – selenium suplex.
THE INFLUENCE OF CADMDIUM LOAD ON THE LEVEL OF VITAMINS A AND E IN BLOOD OF LAYING HENS
Authors: Ostapyuk A. Y. , Gutyj B. V.
Published: August 2020

Cadmium – a heavy metal, classified as a second class of danger, has a pronounced tendency to accumulate in the body. Absorbed cadmium accumulates in the liver as a complex with metallothionein. The aim of the study was to study the effect of Cadmium on the level of vitamins A and E in the blood of laying hens. For research, three groups of poultry were formed: control and two experimental. The control group chickens were on a regular diet, fed with compound feed and drinking water without cadmium sulfate. To drinking water of chickens of experimental groups for 30 days was added cadmium sulfate in doses: the first group – 2 mg/kg, the second group – 4 mg/kg of body weight. The keeping conditions of the chickens and the indoor microclimate parameters for all groups of birds were similar.

After cadmium loading at a dose of 2 mg/kg body weight, the level of vitamin A in the blood of chickens has probably decreased since the 14th day of the experiment. It was the lowest at 21 days of experience. When drinking cadmium sulfate at a dose of 4 mg/kg body weight decreased levels of vitamin A by 4 and 21 days of the experiment, respectively, by 24 and 40% compared with the control group of chickens.

When examining the level of vitamin E in the blood of laying hens under cadmium loading, it was found that in the second experimental group of chickens the level of this vitamin was significantly lower than in the control and the first experimental group of chickens. When compared with the control group of chickens, it was found that on the 14th day of the experiment, the level of vitamin E was lower in the first experimental group by 12% and in the second – by 27%, respectively. At day 21 of the experiment, the level of vitamin E was the lowest in the second experimental group, where it was 0.70 ± 0.011 µg/ml, respectively, which is 44% lower than the control.

A significant decrease in the content of vitamins A and E indicates not only the pathological condition of the liver, but also the enhancement of oxidation processes associated with a decrease in the activity of enzymes of the antioxidant system. Cadmium compounds have high biological activity, they easily form complex compounds with proteins, nucleic acids, which inactivate a number of enzymes.
MACROSCOPIC CHANGES IN EXPERIMENTALLY DAMAGED TIBIA OF RABBITS WHEN ALLOGENEIC MESENCHYMAL STEM CELLS WERE INTRODUCED IN DIFFERENT WAYS
Authors: Savchuk T. L. , Bokotko R. R. , Kharkevych Yа. О. , Mazurkevych A. Y. , Malyuk M. O. , Danilov V. B. , Blahyi R. S. , Braha O. V.
Published: August 2020

The article presents the results of studying macroscopic changes in the tibia of rabbits during experimental mechanical damage after leading allogeneic mesenchymal stem cells to the jugular vein and directly to the site of bone damage.

Bone damage was modeled on 3-month-old chinchilla rabbits in the middle third of the tibial shaft. Macroscopic studies of the process of restoration of the tibial defect were carried out on 3, 7, 14, 21, 28 and 42 days. Our macroscopic studies of the healing of a tibial defect indicate a difference in the regeneration processes in rabbits of the control group and experimental groups after the use of allogeneic mesenchymal stem cells.

It was found that the introduction of allogeneic mesenchymal stem cells, regeneration processes are faster for 3 days in the area of damage, there are no blood clots, and in the subsequent phases of regenerative osteogenesis, the reaction of adjacent soft tissues, the formation of bone corns and its reduction in volume, accelerated. Almost complete restoration of the defect due to the introduction of allogeneic mesenchymal stem cells occurs on the 28 day. While in the control group of animals, it ends only at 42 days.

In addition, it was found that the introduction of allogeneic mesenchymal stem cells directly to the site of injury regeneration processes in the area of the created bone defect are more intensively expressed in the first and subsequent phases of regeneration than in animals after the use of allogeneic mesenchymal stem cells intravenously.

The obtained data can be used to restore damaged bone tissue using stem cells, as well as for further experimental studies.
DIETARY IMPACTS ON EARLY RUMEN MICROBIOTA DEVELOPMENT IN CALVES
Authors: Shkromada O. I. , Ulko L. G. , Udovenko Ya. S.
Published: August 2020

The rumen is an important digestive organ in which fermentation processes take place. Improving the rumen development of growing cattle is one of the major tasks. The need for ruminants in amino acids is as great as in mono-gastric animals. The rumen microorganisms cannot synthesize microbial protein in sufficient quantity to cover the need of developmental growth.

The experiments were conducted on calves from four to five months of age at the «Za myr» farm in Sumy district, Sumy region. The calves were divided into three experimental groups of 10 animals each. The first experimental group was fed powder not protected methionine at a dose of 10 grams per animal, the second group was fed granulated methionine at a dose of 10 grams per animal for a month.

The results suggest that bacterial count increased by 84,3%; Paramecium caudatum by 29,4 %; Entodiniomorpha by 26,6 % in the first experimental group to the 30th day. In the second group the indicators also changed after a month of research. The bacterial count was 93,2 % higher; Paramecium caudatum by 42,5 %; Entodiniomorpha by 25,9 % compared to control.

According to the results of the experiment, we can assumed that powder methionine as well as granular had a positive effect on the qualitative and quantitative composition of the rumen microflora. In the first experimental group content of total nitrogen was higher by 12,2 % and protein content by 19,6 % compared to controls. In the second experimental group, where calves were fed a granulated methionine, content of total nitrogen was higher by 15,6 % and protein content by 22,4 % compared to controls. The residual nitrogen concentration significantly decreased by 32,2 % in the first group of calves and by 29,9 % in the second.

It was experimentally proved that the enriched of granulated and non-granulated methionine food additives helped to increase the number of microorganisms in the rumen and increase the concentration of nitrogen in the rumen.
Hubungan Asupan Vitamin B12 dengan Kadar Hemoglobin pada Vegetarian di Vihara Maitreya
Authors: Serlie Serlie , Winaktu Gracia JMT , Sinsanta Sinsanta , Winata Susanty Dewi
Published: August 2020

Minat terhadap gaya hidup vegetarian semakin meningkat karena orang-orang semakin sadar manfaat menjadi vegetarian. Namun, pola makan vegetarian dapat menyebabkan beberapa kerugian, salah satunya adalah kekurangan vitamin. Vitamin B12 hanya dapat ditemukan secara alami pada hewan, sehingga kekurangan vitamin B12 kemungkinan besar terjadi pada vegetarian. Penelitian ini bertujuan untuk mengetahui hubungan antara asupan vitamin B12 dengan kadar hemoglobin pada vegetarian. Pada penelitian cross-sectional  ini, tujuh puluh empat vegetarian di Vihara Maitreya Dutamas mengikuti penelitian pada bulan Februari 2020. Pengumpulan data dilakukan dengan pengisian kuesioner Semi-Quantitative Food Frequency Questionnaire  dan pemeriksaan kadar hemoglobin dengan Hb meter. Studi ini mendapatkan hasil bahwa sebagian besar responden (85,1%) tidak mengalami anemia. Responden (60,8%) memiliki asupan vitamin B12 yang cukup dan sebagian besar (39,2%) tidak mengonsumsi suplemen vitamin B12. Dapat disimpulkan bahwa tidak ada hubungan yang bermakna antara asupan vitamin B12 dengan anemia (P = 0,057) pada vegetarian di Vihara Dutamas.
KAJIAN KARAKTER FISIOLOGIS VARIETAS PADI SAWAH PADA BUDIDAYA SECARA ORGAN
Authors: AZIEZ ACHMAD FATCHUL , Agus Budiyono  , Daryanti  , Wiyono  , Setie Harieni  , Dwi Susilo Utami
Published: August 2020

The reality in the field shows that not all lowland rice varieties which include local varieties, old superior varieties, new superior varieties and new types of varieties are suitable for organic cultivation because each group of varieties has different physiological characters. This research was carried out with the aim of determining the suitable lowland rice varieties for organic cultivation based on physiological characters.               The research was carried out through pot experiments to determine the suitability of lowland rice varieties including local varieties, old varieties, new varieties, and new types of superior varieties in organic cultivation based on their physiological characteristics. with an altitude of 113 m above sea level with inceptisol soil types and tropical climate.               The results showed that organic cultivation did not reduce root permeability to N uptake except for Cisedane variety. Organic cultivation lowered the KPK for the roots of the IR64, Cianjur and Mentikwangi varieties, but increased the KPK for the roots of the Pandanwangi and Cisedane varieties. The uptake rate of N, P, and K roots in organic cultivation was not different from conventional cultivation. The uptake of N roots in organic cultivation was lower than conventional cultivation. The uptake of N, P, and K by roots between varieties was not different. Organic cultivation reduced the uptake of N stems of varieties IR64, Mentikwangi and Cisedane. Among the varieties tested, there was no difference in N uptake in conventional or organic cultivation. Organic cultivation reduced the P uptake of stems of IR64 and Mentikwangi varieties, Organic cultivation decreased total N uptake of Mentikwangi varieties. In conventional and organic cultivation, the plant N uptake of all tested rice varieties was no different.
FAKTOR-FAKTOR YANG MEMPENGARUHI PENDAPATAN USAHA TANI BAWANG DAUN (Allium fistulosum L) (STUDI KASUS DI KECAMATAN BERGAS KABUPATEN SEMARANG)
Authors: Agung Prasetyo
Published: August 2020

Spring onion was a type of food plant that has long been known and cultivated in developing countries. Bergas District, Semarang Regency, has an area that makes scallions a leading agricultural sector. This study aimed to determine the factors that affect the income of leek farming. The method of determining the location used was purposive with simple random sampling for Collecting samples. Data analysis using OLS with the Cobb Douglas function. The results showed that the factors of land area, labor, seeds, and manure had a significant effect on the income of leek farmers. More efforts are needed to innovate and have the courage to cultivate leeks not only with an intercropping system so that income from farming can be higher.
CELEIDA TOSTES E SEU MURO DE RESISTÊNCIA: ACERCAMENTOS SOBRE METODOLOGIA DE ENSINO DE UMA PROFESSORA-ARTISTA / Celeida Tostes and her wall of resistance: approaches on teaching methodology of an educator-artist
Authors: Novaes Mariana
Published: August 2020

Este texto é um acercamento de determinados procedimentos artísticos que envolvem o corpo desde a década de 1960 até a atualidade, tendo como balizadora a articulação entre processo criativo e ensino de arte. Para tanto, busca uma aproximação do projeto artístico da artista e professora Celeida Tostes, admitindo que suas proposições trazem elementos fundantes dos procedimentos que a arte brasileira atual apresenta. Suas ações no campo do ensino e no campo da arte, muitas das vezes indiscerníveis, constituem referência histórica como núcleo de resistência atravessador de vários contextos. Esta atualização, que se permite apontar para os trabalhos de Celeida Tostes e trazê-los à luz por um pensamento mais conciliador e menos excludente, se construiu com autores de áreas diversas além do pensamento da própria artista.Palavras-chave: Celeida Tostes; Arte relacional; Práticas colaborativas.AbstractThis text is about certain artistic procedures involving the body from the sixties to the present, marked as a link between the creative process and art teaching. Thus, seek an update of the artistic project from artist and teacher Celeida Tostes, admitting that its propositions bring founding elements of the procedures that the actual brazilian art shows. Her actions in the teaching and art field, many times indiscernible, they constitute a historical reference as a core of resistance across different contexts.This update, which can point to the work of Celeida Tostes and bring them to a thought more conciliatory and less exclusive, was built with authors from others areas besides the artist´s thinking.Keywords: Celeida Tostes; Relational arts; Collaborative practices.
IN-BETWEEN: IMBRICAÇÕES ENTRE ARTE, CIDADE E INSTITUIÇÃO NA OBRA VAZADORES DE RUBENS MANO / In-between: the imbrications between art, city and institution in the vazadores’ work of Rubens Mano
Authors: Ferraz Tatiana Sampaio
Published: August 2020

Estudo de vazadores em seus múltiplos aspectos -- espaciais, artísticos, institucionais e políticos. A escolha da obra de Rubens Mano pressupõe uma perspectiva contextualista renovada da arte contemporânea sobre a cidade, que tensiona a obra na direção de um híbrido capaz de transitar entre os mundos artístico e extra-artístico, atenta estética e politicamente aÌ€ problemática urbana.Palavras-chave: Rubens Mano; Vazadores; Arte contemporânea; Espaço público.AbstractRubens Mano study of the work, in its multiple aspects - spatial, artistic, institutional and political. The artist's choice presupposes a renewed contextualist perspective of contemporary art on the city, which stresses the work towards a hybrid capable of transiting between the artistic and extra-artistic worlds, aesthetically and politically attentive to the urban problematic.Keywords: Rubens Mano; vazadores; contemporary art; public space
O IMPOSSÍVEL DIZER DE LEILA DANZIGER: (DES)ESCRITA, APORIA E ESPANTO / The impossible saying of Leila Danziger: (dis)writing, aporia and amazement
Authors: Fernandes Thiago Grisolia
Published: August 2020

Este artigo lança um olhar sobre a noção de apagamento na obra da artista e poeta Leila Danziger, a partir do procedimento de arrancar a camada mais superficial de folhas de jornal, presente em vários de seus trabalhos. Pensando sua produção plástica e poética a partir deste mesmo procedimento, desdobramos conceitos como os de aporia, testemunho e desescrita, recorrendo a pensadores como Jean-Luc Nancy, Paul Celan e Jacques Derrida, contribuindo para a construção de um campo ampliado da poesia.Palavras-chave: Leila Danziger; Apagamento; Aporia.AbstractThis article takes a look at the notion of erasure in the work of the artist and poet Leila Danziger, based on the procedure of removing the most superficial layer of newspaper sheets, present in several of her works. Thinking about his plastic and poetic production based on this same procedure, we unfold concepts such as aporia, testimony and diswriting, using thinkers like Márcio Seligmann-Silva, Jean-Luc Nancy, Paul Celan and Jacques Derrida, contributing to the construction of an expanded field of poetry.Keywords: Leila Danziger; Erasure; Aporia.
ROUPAS COMO CORPOS: O AGENCIAMENTO POLÍTICO DO VESTUÁRIO POR CHRISTIAN BOLTANSKI / Clothes as bodies: the political agency of clothing by Christian Boltanski
Authors: Adverse Angélica
Published: August 2020

O artigo aborda o agenciamento das roupas no trabalho do artista Christian Boltanski. Partindo da dimensão do poder dos corpos têxteis, analisaremos como as roupas investem-se das palavras emudecidas dos corpos ausentes, constituindo-se como alegoria do testemunho e do documento histórico. A ideia central é pensar como as roupas explicitam a aniquilação humana provocada pelos regimes políticos totalitários. Analisaremos como as instalações Prendre la Parole (2005) e Personnes(2010) desvelam a presença-ausência da vida-morte na experiência política do discurso têxtil.  Palavras-chave: Roupas; Corpos; Agenciamento; Política; Memória.AbstractThe article addresses the agency of clothes in the work of the artist Christian Boltanski. Starting from the dimension of the power of the textile bodies, we will analyze how the clothes invest themselves with the muted words of the absent bodies, constituting themselves as an allegory of the testimony and of the historical document. The central idea is to think about how clothes make explicit human annihilation brought about by totalitarian political regimes. We will analyze how the installations Prendre la Parole (2005) and Personnes (2010) reveal the presence-absence of life-death in the political experience of textile discourse.Keywords: Clothes; Bodies; Agency; Politics; Memory.
BORDADOS, SONHOS E PESADELOS: DESLOCAMENTOS DE TRAUMAS E OBJETOS DOMÉSTICOS NA OBRA DE ROSANA PALAZYAN / Embroidery, dreams and nightmares: displacement of traumas and domestic objects in the work of Rosana Palazyan
Authors: Rebesco Vanessa Lúcia de Assis
Published: August 2020

O objetivo deste texto é analisar a série “... uma história que você nunca mais esqueceu?”, da artista Rosana Palazyan, elaborada entre os anos 2000 e 2002. Ainda que não intencionalmente, ao trabalhar com o bordado - prática historicamente depreciada dentro do campo das artes e associada a uma arte dita “feminina” - sobre o travesseiro (objeto considerado doméstico e não artístico), a artista coloca em xeque tanto as noções cristalizadas sobre diferenças sexuais quanto as hierarquias dos gêneros e dos objetos artísticos. Palazyan cria essa série a partir de testemunhos de adolescentes internados em uma instituição no RJ, dedicada à recuperação de jovens infratores. Além de examinar quais sentidos atravessam a utilização do travesseiro e do bordado dentro de uma série que trata de um tema dolorido, discutirei a acolhida dos testemunhos por parte da artista e o lugar de escuta que ela se coloca.Palavras-chave: Rosana Palazyan; Objetos domésticos; Bordado; Testemunho; Trauma.AbstractThe purpose of this text is to analyze the series “... a story that you never forgot?” from the Rosana Palazyan, developed between the years 2000 and 2002. Although not intentionally, when working with embroidery - a practice historically depreciated in the field of the arts and associated with a so-called “feminine art – on the pillow (and object considered domestic and non-artistic), the artist challenges both the crystallized notions about sexual differences and the hierarchies of genres and artistic objects. In addition to examining which meanings cross the use of the pillow and embroidery within a series that deals with a painful theme, we will discuss the acceptance of testimonies by the artist and the place of listening that she places herself.Keywords: Rosana Palazyan; Household objects; Embroidery; testimony; Trauma.
CORPO E AUTOEXPERIMENTAÇÃO: UMA LEITURA DA ARTCHARNELDE ORLAN A PARTIR DO PENSAMENTO PÓS-FEMINISTA DE PAUL B. PRECIADO / Body and self-experimentation: a reading of ORLAN's artcharnel from Paul B. Preciado's post-feminist thinking
Authors: Rodrigues Rejane Lopes
Published: August 2020

A partir da década de 1960 teve início na Europa e nos EUA um novo movimento artístico conhecido como arte performativa. ORLAN, artista plástica francesa, insere-se neste movimento através de obras que incluem intervenções cirúrgicas em seu próprio corpo com o objetivo de questionar o status do corpo feminino na sociedade ocidental contemporânea. Diante disso, propomos no presente artigo, uma análise do seu trabalho a partir das considerações teóricas do filósofo e escritor transgênero Paul B. Preciado.Palavras-chave: Arte performativa; ORLAN; Gênero; Feminismo; Paul. B. Preciado.AbstractFrom the 1960s, a new artistic movement known as performative art began in Europe and the USA. ORLAN, a French artist, is part of this movement through works that include surgical interventions on her own body in order to question the status of the female body in contemporary Western society. Therefore, in this article, we propose an analysis of his work based on the theoretical considerations of the transgender philosopher and writer Paul B. Preciado.Keywords: Performative art; ORLAN; Genre; Feminism; Paul B. Preciado.
Polyplex: A Promising Gene Delivery System
Authors: Aggarwal Rohan , Targhotra Monika , Kumar Bhumika , Sahoo P.K , Chauhan Meenakshi K
Published: August 2020

In the past few years gene delivery system has gained a huge attention owing to its proved efficacy in several diseases especially in those caused by genetic and/oroncological malfunctioning. The effective gene delivery mainly depends on the carrier molecules that can ensure the safe and specific delivery of the nucleic acidmolecules. Viral vectors have been used for a longer period as the gene transfer vehicle. However, these viral vectors have potential immunological disadvantages that made them less preferred. Recently, non-viral vectors such as polyplexes have emerged as a promising alternative for viral vectors. Polyplexes are formed by conjugating a polymer with DNA and in maximum cases the cationic polymers are preferred over others. The structure and stability of the polyplexes depends on various factors. The ability of the polymer to condense the DNA mainly dictates the efficiency of the polyplex mediated transfection. In this review we are going to provide a framework for the synthesis and design of the polyplexes along with the structure and stability of the complexes pertaining to mechanism of action, characterization and therapeutic application, including polyethyleneimine mediated cytotoxicity as well as newer strategies for the generation of better polyplexes.
Liposomal Drug Delivery of Metronidazole for the Local Treatment of Vaginitis
Authors: B. Patel Dhara , K. Patel Jayvadan
Published: August 2020

The present investigation was aimed to formulate liposomes containing metronidazole for local therapy of vaginitis, capable to efficiently deliver entrapped drug during an extended period of time. Liposomes were prepared by simple thin film hydration technique using soya lecithin and cholesterol. Some preliminary trials and 32 factorial design were conducted to optimize the formulation. The drug to Soya lecithin to cholesterol ratio and volume of hydration media were chosen as independent variables. The percentage drug entrapment, particle size and drug release at 12 h were chosen as dependent variables. To achieve application viscosity  and further improve the stability of liposomes,  the prepared liposomes were incorporated in the bioadhasive  carbopol 934P gel (1%), and the system were evaluated for the in vitro drug release and drug stability in phosphate-buffer pH 4.5 and simulated vaginal fluid (VFS) at 37±10C. Stability study for liposome suspension and liposomal gel were carried out. All the performed experiments confirm the applicability of liposomes as a novel drug carrier system for the local treatment of bacterial vaginosis.
Synthesis of Novel Piperonal Derivatives and Evaluation of their Anticonvulsant Activity using A Nanoparticular Formulation
Authors: Aukunuru Jithan , Eedula Keerthana , Pasham Venkanna , Katla Venumadhav , Reddy K Srinivas
Published: August 2020

Ancient Chinese medical literature and independent studies indicate that piperine possess anticonvulsant activity and demonstrates a high degree of safety. A similarity was also demonstrated with synthetic piperine derivatives as well. In this study, chalcones and Schiffs bases of piperonal with different any methyl ketones, and aromatic primary amines were synthesized using conventional and microwave-irradiation methods. Purification of these compounds was  effected by recrystallization from alcohol and characterized by NMR and IR spectra. The synthesized compounds were screened for their anticonvulsant activity using a 4-aminopyridine induced model with the help of a conventional and a current nanoparticular formulation approach. A drug delivery system methodology in the form of nanoparticles for screening was adopted because it has more advantages when compared to conventional formulations in drug discovery stages. Nanoparticle formulations encapsulating selected synthesized compounds were prepared using solvent evaporation technique by taking polycaprolactone as the polymer. Few piperonal synthesized derivatives demonstrated anticonvulsant activity which was lesser than the standard phenytoin. Unfortunately, nanoparticular formulations prepared in this current study encapsulating selected synthesized compounds did not show any activity, suggesting more work is needed to demonstrate positive results.