bluuebunny/crossref_metadata_2025 huggingface dataset:
Data Management Maturity for Knowledge-Based Decision-Making
Authors: Palonka Joanna
Published: October 2017

Nowadays, information has been recognized as a strategic asset of an organization. There are numerous best practices for ensuring good quality data and establishing data management frameworks that are required to provide quality information for the management decision-making process. Unlike most data management studies, which focus on large enterprises and SMEs, this study deals with organizations from the third sector in Poland, comprising e.g. associations, foundations, faith-based organizations, etc. The aim of the chapter is to determine the organizations' maturity level of data management for decision-making processes in management. A survey was conducted to gather data from the organizations. The chapter utilizes samples that were collected from Slaskie Voivodship. The conclusions of the present research can help in creating and implementing a model of the data-driven decision-making process so that the operations of these organizations can be enhanced and improved.
Knowledge Management and Organizational Performance in Service Industry
Authors: Maroofi Fakhraddin
Published: October 2017

This study examines a comprehensive model and the relationships between organizational factors and KM process. Information is collected from human resource managers and general managers operating in 102 service corporations. In this chapter author has used hierarchical regression analysis and exploratory factor analysis to planned hypotheses. When dominant for the consequences of transactional leadership, the results indicate the transformational leadership positively affects KM processes and organizational performance, and it is well established that transformational leadership foresaw organizational performance, thereby reflecting that its transformational leaders make vital contributions to amass, transfer, and apply knowledge within the organizations. Further, in transactional leadership, when dominant, the consequences in KM process mediates the link between transformational leadership and organizational performance.
Assessment of Graduates' Generic Competences in Virtual Mode at the National Polytechnic Institute
Authors: Espinosa Edgar Oliver Cardoso , Londoño Mayra Alejandra Vargas
Published: October 2017

The main objective of the study was to assess the levels of development of generic competences in the graduates of the degree in International Commerce in the virtual modality of the IPN. The type of research was a quantitative methodology with an exploratory cross-sectional design. The instrument that was used to obtain the information on the GCs developed was a questionnaire based on a Likert scale. It was found that the assessment of the participants on this type of competences has an interval based on a lower mean of 2.13 until a larger average of 3.71, where those that were identified with the lowest level of dominance were the ones related to the work in international contexts, second language communication skills and the ability to work as a team. The findings serve to support its virtual academic programs and thus increase its academic offer based on quality indicators that include not only graduates but also other educational actors such as teachers, managers and administrators as well as assessing the operation of the support infrastructure and equipment.
Interaction in Distance Education
Authors: Kumtepe Evrim Genc , Sen Ersoy Nazife
Published: October 2017

Education is a product of the objects and actors in the process of interaction. Interaction is, therefore, an important factor that affects the quality and sustainability of education. For this reason, this section will focus on interaction and its theories and approaches which are a popular and versatile concept in distance education. In the first part of the chapter, the concept of interaction will be discussed with different dimensions and components. Interaction in the following section will be examined within the framework of Moore's Theory of Transactional Distance, Anderson's Interaction Equivalency Theorem, and Gorsky and Caspi's Theory of Instructional Dialogue. At the end of the chapter, the nature of the interaction in distance learning will be discussed in the context of the studies on instructional dialogue and the cross-cultural comparisons will be addressed to the issue of the role of interaction in distance settings.
What I Think I Heard You Say
Authors: Sechrest-Ehrhardt Lisa
Published: October 2017

The United States is a diverse country which includes a vast tapestry rich in cultures, ethnicities, languages, and religions. The robust diversity is what defines the nation, its character, its identity, and its strength. This rich tapestry of diversity also provides the nation with a unique status among all nations and is viewed as a nation of immigrants. One aspect of such diversity is the complicated nature of social interactions between and among people who have different perceptions about the world. Often one's perception effects behavior in social interactions having positive or negative results. Using two theories, Symbolic Interaction and Cognitive, this chapter guides the reader to understanding the complicated relationships that arise when one interacts with and among others who may not perceive the world in the same manner.
Inverted Constructivism to Leverage Mobile-Technology-Based Active Learning
Authors: Lim Doo Hum , Tschopp-Harris Kristie
Published: October 2017

The classroom environment in the 21st century has increasingly utilized many types of technologies as supplemental tools for teaching and learning including instructional design, development, and delivery. The level at which schools are encompassing more technology is often restrained by financial constraints and rapid advances in the static equipment, making the equipment outdated within a short period of time. However, the use of relatively low cost mobile technologies such as tablets and cell phones in the classroom setting have reduced the social and logistical barriers in education and enhanced the creative active learning processes. The primary objective of this chapter is to offer insights into the importance of using mobile technology to educate students in today's connected society and to identify the multi-faceted advantages of mobile technology within an active learning curriculum design to encourage a meaningful learner-centered experience.
Problem-Based Learning
Authors: Ampadu Ernest , Adjei-Boateng Emmanuel
Published: October 2017

Students learning and understanding is enhanced if the teaching and learning process is authentic. Authentic learning process leads to understanding and meaningful application of concepts learned. One way by which teachers can to provide authentic learning environment is through Problem-Based Learning (PBL). PBL offers opportunity for students to learn about something that is real and beneficial. Teacher education programs, pre-service or in-service, should help teachers to understand how to use PBL to provide students with authentic learning environments. The chapter aims at supporting teachers' understanding and application of PBL so that they can provide students with meaningful learning experiences. Specifically, this chapter is intended to assist teachers have a better understanding of PBL as a strategic approach to meaningful teaching and learning as well as identify effective ways to incorporate this approach into their pedagogical practices.
Mobile-Assisted-Learning Approach in Enhancing the Student Teacher's Vocabulary and Usage of Mobile Phone
Authors: Dange Jagannath K.
Published: October 2017

Mobile learning facilitates delivery of learning using portable electronic devices. This study investigated the effectiveness of mobile assisted learning in the development of vocabulary and usage of mobile phone. Specifically, the primary objectives of the study were to compare the effectiveness of Mobile Assisted Learning Approach and Conventional Learning Approach with reference to Vocabulary and Usage of Mobile Phone and also to analyze the interaction between treatments with gender and subject background in reference to developing vocabulary and usage of mobile phone. Mobile Assisted Learning Approach was found to be more effective in developing Vocabulary and Usage of Mobile Phone. The study has broad implications for student teachers of the professional colleges. These findings should be taken into consideration educational administrators in secondary and higher education teacher training institutions.
Foundational Processes, Home-School Partnerships, and Culturally Responsive Practices for Dual Language Learners
Authors: Howlett Kristina M. , Kindall Heather D.
Published: October 2017

The purpose of this chapter is to examine the current empirical studies on foundational processes, home-school partnerships, and culturally responsive practices in regard to Dual Language Learners (DLLs) for early childhood education in order to inform teacher education programs (TEPs).
Pushing In
Authors: Cowdery Joy
Published: October 2017

This chapter examines the research that encourages co-teaching between the content specialist and the ESL teacher as a delivery model. Many schools are making a shift from ESL pull-out to ESL – mainstream co-teaching, or pushing in, because research suggests that co-teaching can be one of the most effective ways to meet the needs of the growing ESL population (Causton-Theoharis, 2008; Honigsfeld & Dove, 2008; Young, Smith, 2006). Collaborative teaching relationships are productive and rewarding, but of greater importance, ELL student achievement increases substantially in co-taught classes. Suggestions for enhancing the co-teaching experience for teachers and students is disseminated and analyzed.
Intercultural Competence for Teachers of Young ELLs
Authors: Yeh Ellen , Wan Guofang
Published: October 2017

Language educators encounter challenges of integrating meaningful cultural content and assessment into ELL curricula, mainly due to inadequate professional support and training. Regardless of the growing number of young language learners and institutes around the globe, very limited studies have been conducted and published regarding young ELLs' intercultural competence (IC) development. The American Council on the Teaching of Foreign Languages (ACTFL) Global Competence Position Statement (2014) reinforces the importance of teachers helping learners deal with these challenges. This chapter conducted qualitative meta-analysis reviewing the existing literature on the various models of IC teacher preparation programs for young ELLs aiming to improve the IC components in teacher preparation curricula. The main components of IC to be infused into curricula include: (1) the educational needs and state standards of IC in teacher education programs; (2) IC theoretical frameworks and assessment models; and (3) IC practices in teacher education for young ELLs.
Multimodal and Community-Based Literacies
Authors: Harman Ruth , Shin Dong-shin
Published: October 2017

In recent decades, high-stakes school reforms and draconian budget cuts have constrained the autonomy of public school teachers in developing multi literacy approaches with emergent bilingual learners (e.g., English-only laws, high stakes testing). This chapter describes the community and multimodal instructional practices of two urban elementary school teachers/ researchers, developed in the context of a professional development initiative. Using critical, sociocultural conceptions of literacy and qualitative methods of investigation, the paper investigates different aspects of the teachers' writing instruction (i.e., community involvement; genre-based instruction; digital literacy; and multimodality); it also explores how the writing processes of focal bilingual students incorporated these practices. Findings show that this approach positioned bilingual learners as agentive text makers. In addition, the second-grade students developed a heightened awareness of audience and context. Implications are discussed, including the pressing need for teacher collaboration, robust school-university partnerships, and innovative multimodal approaches to literacy.
Phonemic Awareness and Literacy Development in Young English Learners With Non-Alphabet-Based Home Language
Authors: Shim Jenna Min
Published: October 2017

This chapter examines a widely accepted assumption that phonemic awareness is a precursor to early literacy development through a review of existing research studies in the field of phonemic awareness, early literacy acquisition and development and bilingual literacy acquisition and development. Based on a foundation that success in early literacy acquisition has a significant impact on students' later academic success, the author argues that unconditionally and uncritically accepting the view that phonemic awareness and literacy development are positively correlated can exclude many English learners (ELs) from learning opportunities and thus from later academic success. The author concludes that if educators are committed in providing equitable education for all students, we should not assume that all ELs have the same needs in early literacy acquisition instruction, and to do otherwise is to marginalize ELs especially the ones whose first language system bears no resemblance to that of English.
Graves’ disease thyrotoxicosis and propylthiouracil related agranulocytosis successfully treated with therapeutic plasma exchange and g-csf followed by total thyroidectomy.
Authors: Candoni Anna
Published: October 2017

Antithyroid drugs can be a rare cause of agranulocytosis (0.5% of treated patients). Suspension of these drugs is mandatory in these patients and may result in worsening hyperthyroidism. We report the case of a 27-year-old woman who is 3 months post-partum, breastfeeding, and suffering from Graves’ disease hyperthyroidism treated first with methimazole and then with propylthiouracil due to a methimazole allergy. She was admitted for urosepsis and agranulocytosis. The patient was diagnosed with propylthiouracil related agranulocytosis, diffuse toxic goiter, and thyro-gastric syndrome. Antithyroid drug therapy was stopped resulting in a worsening of thyrotoxicosis. Agranulocytosis was treated with 8 doses of G-CSF with full recovery. To rapidly restore euthyroidism and to perform a thyroidectomy, the patient received 6 plasmapheresis procedures, to clear thyroid hormones and anti-TSH receptor antibodies from the blood, resulting in a pre-surgical euthyroid state without antithyroid drugs. One year after thyroidectomy, the patient is well on thyroid hormone replacement therapy. Key Words: Plasmapheresis; Hyperthyroidism, Agranulocytosis; Propylthiouracil.
Transfusion-related acute lung injury (TRALI) in two thalassaemia patients caused by the same multiparous blood donor
Authors: Kontoghiorghes George J
Published: October 2017

Two separate episodes of transfusion-related acute lung injury (TRALI) in thalassaemia patients caused by red blood cell transfusions from the same multiparous blood donor are reported. Both cases had the same symptomatology and occurred 10-60 minutes of transfusion. The patients presented dyspnea, sweating, fatigue, dizziness, fever, and sense of losing consciousness. The chest x-ray showed a pulmonary oedema-like picture with both lungs filled with fluid. The patients were treated in the intensive therapy unit. They were weaned off the ventilator and discharged following hospitalization 7 and 9 days respectively. The TRALI syndrome was diagnosed to be associated with HLA-specific donor antibodies against mismatched HLA-antigens of the transfused patients. Haemovigilance improvements are essential for reducing the morbidity and mortality in transfused patients. Blood from multiparous donors should be tested for the presence of IgG HLA-Class I and –Class II antibodies before being transfused in thalassaemia and other chronically transfused patients.
Impact of pitch angle fluctuations on airborne lidar forward sensing along the flight direction
Authors: Gurvich Alexander Sergeevich , Kulikov Victor Alexeevich
Published: October 2017

Abstract. Airborne lidar forward sensing along the flight direction can serve for notification of clear air turbulence (CAT) and help to prevent injuries or fatal air accidents. The validation of this concept was presented in the framework of the DELICAT (DEmonstration of LIdar-based CAT detection) project. However, the strong variations in signal level, which were observed during the DELICAT measurements but not explained, sometimes indicated the need of a better understanding the observational errors due to geometrical factors. In this paper, we discuss possible error sources pertinent to this technique, related to fluctuations of the flight parameters, which may lead to strong signal variations caused by the random deviations of the sensing beam from the forward flight trajectory. We analyze the variations in backscattered lidar signal caused by fluctuations of the most important forward-sensing flight parameter, the pitch angle. The fluctuation values considered in the paper correspond to the error limits of the compensational gyro platform used in civil aviation. The part of the pitch angle fluctuations not compensated for by the beam-steering device in the presence of aerosol concentration variations can lead to noticeable signal variations that can be mistakenly attributed to wind shear, turbulence, or fast evolution of the aerosol layer. We formulate the criteria that allow the recognition of signal variations caused by pitch angle fluctuations. Influence of these fluctuations is shown to be stronger for aerosol variations on smaller vertical scales. An example of DELICAT observations indicating a noticeable pitch angle fluctuation impact is presented.
Revisiting the synoptic-scale predictability of severe European winter storms using ECMWF ensemble reforecasts
Authors: Pantillon Florian , Knippertz Peter , Corsmeier Ulrich
Published: October 2017

Abstract. New insights into the synoptic-scale predictability of 25 severe European winter storms of the 1995–2015 period are obtained using the homogeneous ensemble reforecast dataset from the European Centre for Medium-Range Weather Forecasts. The predictability of the storms is assessed with different metrics including (a) the track and intensity to investigate the storms' dynamics and (b) the Storm Severity Index to estimate the impact of the associated wind gusts. The storms are well predicted by the whole ensemble up to 2–4 days ahead. At longer lead times, the number of members predicting the observed storms decreases and the ensemble average is not clearly defined for the track and intensity. The Extreme Forecast Index and Shift of Tails are therefore computed from the deviation of the ensemble from the model climate. Based on these indices, the model has some skill in forecasting the area covered by extreme wind gusts up to 10 days, which indicates a clear potential for early warnings. However, large variability is found between the individual storms. The poor predictability of outliers appears related to their physical characteristics such as explosive intensification or small size. Longer datasets with more cases would be needed to further substantiate these points.
Juan Ginés de Sepúlveda frente a León de Castro: una carta inédita en defensa de su traducción latina de la política de Aristóteles
Authors: J. García Pinilla Ignacio , Solana Pujalte Julián
Published: October 2017

En este artículo se edita y traduce un documento en forma epistolar desconocido hasta ahora. Contiene la respuesta de Juan Ginés de Sepúlveda a algunas críticas vertidas por León de Castro a la traducción latina de la Política de Aristóteles publicada por el primero en 1548. Además de ofrecer un nuevo ejemplo del helenismo en Castilla en el siglo XVI, permite conocer no solo los puntos de vista de ambos eruditos sobre pasajes controvertidos de la obra aristotélica, sino también nuevos detalles sobre la actividad fi lológica de Sepúlveda y los materiales en los que se apoyó.
Gentle endodiathermy of retinal vessels to mark paravascular posterior retinal breaks in highly myopic eyes
Authors: Ricci Giuseppe D’Amico , Pinna Antonio , Boscia Francesco , Sborgia Giancarlo , Giancipoli Ermete
Published: October 2017

Purpose:

To show a new method to highlight posterior paravascular retinal breaks, responsible for posterior retinal detachment in highly myopic eyes, by gentle endodiathermy on the nearby retinal vessel, in areas of patchy chorioretinal atrophy.

Methods:

A standard 25-gauge (25-G) 3-port pars plana vitrectomy with internal limiting membrane (ILM) peeling was performed. A gentle endodiathermy was applied on the vessel close to the retinal break until a clear withe spot became visible. This spot was used as a landmark to identify the retinal break after fluid-air exchange.

Results:

The retina was attached after a single operation and no retinal redetachment was reported. A complete blood flow restoration in the treated vessel was documented with fluorescein angiography after 5 days.

Conclusions:

This simple technique may help the vitreoretinal surgeon to identify paravascular retinal breaks after fluid-air exchange. No damage to the retinal vessels undergoing endodiathermy was observed.
Comparative study of unilateral versus bilateral inferior oblique recession/anteriorization in unilateral inferior oblique overaction
Authors: Mostafa Attiat M. , Kassem Rehab R.
Published: October 2017

Purpose:

To compare the effect of, and the rate of subsequent development of iatrogenic antielevation syndrome after, unilateral versus bilateral inferior oblique graded recession-anteriorization to treat unilateral inferior oblique overaction.

Methods:

Thirty-four patients with unilateral inferior oblique overaction were included in a randomized prospective study. Patients were equally divided into 2 groups. Group UNI underwent unilateral, group BI bilateral, inferior oblique graded recession-anteriorization. A successful outcome was defined as orthotropia, or within 2 ∆ of a residual hypertropia, in the absence of signs of antielevation syndrome, residual inferior oblique overaction, V-pattern, dissociated vertical deviation, or ocular torticollis.

Results:

A successful outcome was achieved in 11 (64.7%) and 13 (76.5%) patients in groups UNI and BI, respectively (p = 0.452). Antielevation syndrome was diagnosed as the cause of surgical failure in 6 (35.3%) and 2 (11.8%) patients, in groups UNI and BI, respectively (p = 0.106). The cause of surgical failure in the other 2 patients in group BI was due to persistence of ocular torticollis and hypertropia in a patient with superior oblique palsy and a residual V-pattern and hypertropia in the other patient.

Conclusions:

The differences between unilateral and bilateral inferior oblique graded recession-anteriorization are insignificant. Unilateral surgery has a higher tendency for the subsequent development of antielevation syndrome. Bilateral surgery may still become complicated by antielevation syndrome, although at a lower rate. In addition, bilateral surgery had a higher rate of undercorrection. Further studies on a larger sample are encouraged.
Do the Federal Income Tax Deductions for Home Ownership Benefit the Less Advantage and Average American Family?
Authors: Das Praveen , Boudreaux Denis , Rao S. P. Uma
Published: October 2017

Americans have traditionally placed a high worth on the ability of ordinary families to purchase a home. Even after the devastating financial crisis and the housing bubble in late 2008, according to the September 2014 Country Financial Security Index Survey, more than 89 percent of Americans rank buying a home among the top in achieving American Dream. The financial benefit arising out tax deductions available to homeowners has aided the less advantaged and middle class in achieving this American dream. A simulated model is shown for three families with large home price and income level differences to illustrate the relative economic gains from the federal current tax code to the three families.
Criminaliteitsconcentraties en microplaatsen
Authors: Hardyns Wim , Snaphaan Thom , Pauwels Lieven J.R.
Published: October 2017

Crime concentrations and micro places. A test of the ‘law of crime concentration at places’.

The spatial concentrations of crime are increasingly being studied in smaller units of analysis. This study examines the extent to which crime levels occur at micro places. Weisburd argues there is a law of crime concentration at micro places. His so-called ‘law of crime concentration at places’ states that within an urban context a limited bandwidth of micro places is associated with a specific cumulative proportion of crime (e.g. 25 or 50 percent of crime in a city). In this study the authors investigate Weisburd’s statement in regard to crime concentrations in two large Belgian cities. Official police crime statistics (PCS) for the period 2004-2012 were used. There are several ways to define and operationalize a micro place. Therefore, this study also examines whether the unit of analysis has implications for the concentration of crime at places. Analyses were conducted at two small levels, namely: grid level (using 200 meters by 200 meters grid cells) and the level of the statistical sector (more or less similar to four digit postcode areas or CBS-neighborhoods). This study shows that the concentrations of crime at grid cells are in line with the findings of Weisburd. This trend is consistent in time, for the types of crime as well as for the two cities involved. The concentrations of crime at the level of the statistical sector appear to be less strong and therefore are not in line with the law of crime concentration at places.
Review of the book: „Kształcenie słuchu. Historia – teoria – praktyka. Działalność Międzyuczelnianej Katedry Kształcenia Słuchu w latach 1995–2012”.
[Ear-Training.History – theory – practice. The activity of the Interacademic Chair
of Ear‑Training from 1995 to 2012]
Authors: Wilczyńska Ewa
Published: October 2017

Review of the book: „Kształcenie słuchu. Historia – teoria – praktyka. Działalność Międzyuczelnianej Katedry Kształcenia Słuchu w latach 1995–2012”.
[Ear-Training.History – theory – practice. The activity of the Interacademic Chair
of Ear‑Training from 1995 to 2012]
Report on musical workshops for visually impaired young people
Authors: Suska Anna
Published: October 2017

Report on musical workshops for visually impaired young people
Will Stadler. Palestinian Christians and the Old Testament: History, Hermeneutics, and Ideology
Authors: Krondorfer Björn
Published: October 2017

No abstract is available.
Entre salariat et indépendance : analyse juridique et économique de la relation franchisé-franchiseur
Authors: Coiquaud Urwana , Martin Isabelle
Published: October 2017

Le contrat de franchise consiste à transmettre au franchisé le savoir-faire du franchiseur, moyennant des contreparties financières. Cependant, la transmission de ce savoir-faire va au-delà de la simple mise à disposition d’une « recette ». Elle se prolonge par une assistance de tous les instants délivrée par le franchiseur au franchisé. À certains égards, cette relation contractuelle ne ressemble-t-elle pas à celle d’un employeur avec le salarié ?

Cet article étudie la relation émanant de ce contrat à l’aide des facteurs juridiques (le caractère subordonnant de la relation contractuelle) et économiques (la puissance économique du franchiseur) qui la structurent. L’étude s’appuie tant sur une analyse sociojuridique de la jurisprudence québécoise (1994-2016) au moyen d’une appréhension du contenu relationnel de ce contrat, que sur la littérature économique dans le but de comprendre les éléments de subordination et de puissance économique qui empreignent cette relation.

Le constat révèle que la relation de franchise comporte de fortes composantes de subordination et d’inégalité de puissance économique pour le franchisé, engendrant un assujettissement aussi réel que celui mis en place par le salariat, même s’il n’est pas institué formellement par le contrat de franchisage. Plusieurs pistes d’action sont proposées. Si la requalification de certains contrats de franchise en contrat de travail semble une avenue préconisée par plusieurs pays, nos tribunaux y sont peu enclins. La deuxième piste d’action résiderait dans l’adoption d’une loi encadrant l’établissement et le contenu des contrats de franchise afin de réduire l’asymétrie informationnelle existante entre franchiseur et franchisé, ainsi que de mieux encadrer les qualités du « concept » sur lequel s’appuient les franchiseurs pour séduire les franchisés. Une troisième piste serait de reconnaître l’inégalité de puissance économique, point de départ de la reconnaissance « d’un droit de la dépendance dans l’indépendance » capable d’appréhender ces multiples situations d’entrepreneuriat dépendant dont la franchise n’est qu’un exemple.
The Moral Significance of Death in Georg Simmel’s Metaphysics of Life
Authors: Staiti Andrea
Published: October 2017

In this paper I discuss the significance of Simmel’s conception of death as presented in his capstone work Lebensanschauung (1918). I argue for Simmel death is the form of all cultural forms and that it has a transcendental, form-giving function for life in its concrete unfolding. I conclude with a brief examination of the thought of immortality and some suggestions about how Simmel’s conception of death has a bearing on current issues such as the increment of life-expectancy in developed countries.
Mindfulness in Motion for People with Multiple Sclerosis: A Feasibility Study
Authors: Gilbertson Rachel M. , Klatt Maryanna D.
Published: October 2017

Background:

Mindfulness in Motion is an 8-week mindfulness-based intervention that uses yoga movement, mindfulness meditation, and relaxing music. This study examined the feasibility of using Mindfulness in Motion in people with multiple sclerosis (MS) and the effect of this program on stress, anxiety, depression, fatigue, and quality of life in people with MS.

Methods:

Twenty-two people with MS completed the 8-week mindfulness program as well as assessments 1 week before and after the intervention.

Results:

Pre/post comparison of four self-reported questionnaires—the Mental Health Inventory, 36-item Short Form Health Status Survey, Modified Fatigue Impact Scale, and Five Facet Mindfulness Questionnaire—showed significant improvement in physical functioning, vitality, and mental health. Specifically, improvements were seen in anxiety, depression, and positive affect; cognitive, psychosocial, and overall functioning regarding fatigue; and mindfulness in the areas of observing, acting with awareness, nonjudgment, and nonreactivity.

Conclusions:

Due to the uncertainty in disease progression associated with MS, and the multiplicity of mental and physical symptoms associated with it, programming that addresses anxiety, depression, and fatigue is a key area of future research in MS disease management. Mindfulness in Motion proved to be a feasible program yielding positive results, supporting the need for research to determine the extent to which the program can improve quality-of-life outcomes for people with MS.
Collaboration Between ACGME and AOA Programs to Enhance Success in the Single Accreditation System: A Process Paper
Authors: Weidner Amanda K.H. , Pauwels Judith , McGuire Marcia , Davis Ardis
Published: October 2017

Beginning in 2020, all residency programs will be accredited by the Accreditation Council for Graduate Medical Education (ACGME). Programs accredited by the American Osteopathic Association (AOA) that do not achieve ACGME pre-accreditation status by 2020 will be forced to close, resulting in loss of graduate medical education slots and affecting the physician workforce locally and nationally. Current ACGME programs are in a position to help consult, support, and learn from local AOA-only programs as they work toward meeting ACGME accreditation requirements, but to date there have been only limited collaborations. A regional network of ACGME- and dually accredited family medicine residency programs (“the Network”) and family medicine programs solely accredited by the AOA recognized the imperative to support the AOA-only programs with their accreditation transitions to preserve their primary care residency positions. This article describes the inputs, activities, outputs, and outcomes of these collaborative efforts to establish communications and strategies using a logic model program “road map” format. Initial efforts included a collaborative conference and ongoing consultations and workshops. This model can be replicated for program collaborations in other locations.
First record of the family Sphyrapodidae Guţu, 1980 (Crustacea: Peracarida: Apseudomorpha) with the description of a new species ofSphyrapusfrom the Colombian Caribbean
Authors: Morales-Núñez Andrés G. , Morales-Ruiz Catalina , Ardila Néstor E.
Published: October 2017

A new sphyrapodid tanaidacean,Sphyrapus caribensissp. nov. is described and a new record ofKudinopasternakia siegiis reported for the Colombian Caribbean based on samples collected during cruises in 2014–2015. The new species appears to be most closely related to the northeast Atlantic species,Sphyrapus malleolus. Sphyrapus caribensiscan be distinguished fromSphyrapus malleolusby a combination of characters, including the maxillipedal basis without long distal seta, the number of setae on the distoventral margin of pereopods 1 and 2, and the number of plumose seta on the pleopod basis. A key for the separation ofSphyrapusspecies is presented.
Turbulence in Three‐Dimensional Simulations of Magnetopause Reconnection
Authors: Price L. , Swisdak M. , Drake J. F. , Burch J. L. , Cassak P. A. , Ergun R. E.
Published: October 2017

We present detailed analysis of the turbulence observed in three‐dimensional particle‐in‐cell simulations of magnetic reconnection at the magnetopause. The parameters are representative of an electron diffusion region encounter of the Magnetospheric Multiscale (MMS) mission. The turbulence is found to develop around both the magnetic X line and separatrices, is electromagnetic in nature, is characterized by a wave vector k given by kρe∼(meTe/miTi)0.25 with ρe the electron Larmor radius, and appears to have the ion pressure gradient as its source of free energy. Taken together, these results suggest the instability is a variant of the lower hybrid drift instability. The turbulence produces electric field fluctuations in the out‐of‐plane direction (the direction of the reconnection electric field) with an amplitude of around ±10 mV/m, which is much greater than the reconnection electric field of around 0.1 mV/m. Such large values of the out‐of‐plane electric field have been identified in the MMS data. The turbulence in the simulations controls the scale lengths of the density profile and current layers in asymmetric reconnection, driving them closer to
than the ρe or de scalings seen in 2‐D reconnection simulations, and produces significant anomalous resistivity and viscosity in the electron diffusion region.
Risk of Incident Chronic Obstructive Pulmonary Disease in Rheumatoid Arthritis: A Population‐Based Cohort Study
Authors: Mcguire Katherine , Aviña‐Zubieta J. Antonio , Esdaile John M. , Sadatsafavi Mohsen , Sayre Eric C. , Abrahamowicz Michal , Lacaille Diane
Published: October 2017

Objective

Studies have demonstrated a link between chronic obstructive pulmonary disease (COPD) and inflammation, raising the question whether chronic inflammatory conditions, such as rheumatoid arthritis (RA), predispose to COPD. Our objective was to evaluate the risk of incident COPD hospitalization in RA compared to the general population.

Methods

We studied a population‐based incident RA cohort with matched general population controls, using administrative health data. All incident RA cases in British Columbia who first met RA definition between January 1996 and December 2006 were selected using previously published criteria. General population controls were randomly selected, matched 1:1 to RA cases on birth year, sex, and index year. COPD outcome was defined as hospitalization with a primary COPD code. Incidence rates, 95% confidence intervals (95% CIs), and incidence rate ratios (IRRs) were calculated for RA and controls. Multivariable Cox proportional hazards models estimated the risk of COPD in RA compared to the general population after adjusting for potential confounders. Sensitivity analyses were performed to test the robustness of the results to the possible confounding effect of smoking, unavailable in administrative data, and to COPD outcome definitions.

Results

The cohorts included 24,625 RA individuals and 25,396 controls. The incidence of COPD hospitalization was greater in RA than controls (IRR 1.58, 95% CI 1.34–1.87). After adjusting for potential confounders, RA cases had a 47% greater risk of COPD hospitalization than controls. The increased risk remained significant after modeling for smoking and with varying COPD definitions.

Conclusion

In our population‐based cohort, individuals with RA had a 47% greater risk of COPD hospitalization compared to the general population.
MECOM, HBS1L‐MYB, THRB‐RARB, JAK2, and TERT polymorphisms defining the genetic predisposition to myeloproliferative neoplasms: A study on 939 patients
Authors: Trifa Adrian P. , Bănescu Claudia , Bojan Anca S. , Voina Cristian M. , Popa Ștefana , Vișan Simona , Ciubean Alina D. , Tripon Florin , Dima Delia , Popov Viola M. , Vesa Ștefan C. , Andreescu Mihaela , Török‐Vistai Tünde , Mihăilă Romeo G. , Berbec Nicoleta , Macarie Ioan , Coliţă Andrei , Iordache Maria , Cătană Alina C. , Farcaș Marius F. , Tomuleasa Ciprian , Vasile Kinga , Truică Cristina , Todincă Adriana , Pop‐Muntean Lavinia , Manolache Raluca , Bumbea Horia , Vlădăreanu Ana‐Maria , Gaman Mihaela , Ciufu Cristina M. , Popp Radu A.
Published: October 2017

Polycythemia vera (PV), essential thrombocythemia (ET) and primary myelofibrosis (PMF) are classical myeloproliferative neoplasms (MPN), characterized by specific somatic mutations in JAK2, CALR or MPL genes. JAK2 46/1 and TERT rs2736100 polymorphisms are known to significantly predispose to MPN. This study aimed to establish the additional contribution of the recently described MECOM rs2201862, HBS1L‐MYB rs9376092 and THRB‐RARB rs4858647 polymorphisms to the occurrence of MPN. These three polymorphisms, along with JAK2 46/1 and TERT rs2736100 were genotyped in 939 MPN patients (454 with ET, 337 with PV and 148 with PMF) and 483 controls. MECOM rs2201862 associated significantly with each MPN entity, except for ET, and with all major molecular sub‐types, especially those CALR‐mutated (OR = 1.4; 95% CI = 1.1‐1.8; P‐value = .005). HBS1L‐MYB rs9376092 associated only with JAK2 V617F‐mutated ET (OR = 1.4; 95% CI = 1.1‐1.7; P‐value = .003). THRB‐RARB rs4858647 had a weak association with PMF only (OR = 1.5; 95% CI = 1‐2.1; P‐value = .04). Surprisingly, JAK2 46/1 haplotype was associated significantly not only with JAK2 V617F‐mutated MPN, but also with CALR‐mutated MPN (OR = 1.4; 95% CI = 1.1‐1.8; P‐value = .01). TERT rs2736100 was associated equally strong with all MPN, regardless of phenotype or molecular sub‐type. In conclusion, JAK2 46/1, TERT rs2736100 and MECOM rs2201862 are the chief predisposing polymorphisms to MPN.
Donor lymphocyte infusion and methotrexate for immune recovery after T‐cell depleted haploidentical transplantation
Authors: Gilman Andrew L. , Leung Wing , Cowan Morton J. , Cannon Mark , Epstein Stacy , Barnhart Carrie , Shah Krishna , Hyland Michelle , Fukes Tracy , Ivanova Anastasia
Published: October 2017

CD34+ cell selection minimizes graft‐versus‐host disease (GVHD) after haploidentical donor stem cell transplant but is associated with slow immune recovery and infections. We report a Phase I/II study of prophylactic donor lymphocyte infusion (DLI) followed by methotrexate (MTX) GVHD prophylaxis after CD34‐selected haploidentical donor transplant. A prophylactic DLI was given between day +30 and +42. Rituximab was given with DLI for the last 10 patients. The goal of the study was to determine a DLI dose that would result in a CD4+ cell count > 100/µL at Day +120 in ≥ 66% of patients with ≤ 33% grade II‐III, ≤ 17% grade III, and no grade IV acute GVHD by Day +180. Thirty‐five patients with malignant (n = 25) or nonmalignant disease (n = 10) were treated after CD34‐selected haploidentical donor peripheral blood stem cell transplant. The DLI dose of 5 × 104/kg met the CD4/GVHD goal with 67% of patients having CD4+ cells > 100/µL and 11% grade II‐IV acute GVHD. The cumulative incidence of chronic GVHD was 16%. Fatal viral and fungal infections occurred in 11%. The 2 year estimated overall survival was 69% and the relapse rate was 14% for patients in remission at transplant. There was no effect of NK alloreactivity on relapse. Nine of ten patients at the target DLI dose cohort of 5 × 104/kg are alive with median follow‐up of 18 mos (range 6‐29). Delayed prophylactic DLI and MTX was associated with promising outcomes at the target DLI dose. This trial was registered at clinicaltrials.gov, # NCT01027702.
Efficient Solution‐ and Solid‐State Fluorescence for a Series of 7‐Diethylaminocoumarin Amide Compounds
Authors: Sun Yatong , Sun Yunhui , Zhao Songfang , Cao Duxia , Guan Ruifang , Liu Zhiqiang , Yu Xueying , Zhao Xun
Published: October 2017

A series of 7‐diethylaminocoumarin amide compounds with phenyl (1), benzyl (2), and benzothiazole (3) terminal groups have been synthesized. The crystal structures of compounds 1 and 2 were determined by using single‐crystal X‐ray diffraction. All of these compounds exhibited intense blue fluorescence and high fluorescence quantum yields in both THF (1: 0.36, 2: 0.43, 3: 0.27) and high‐viscosity solvent (glycerol; 1: 0.32, 2: 0.38, 3: 0.41). Compound 1 displayed bright‐yellow–green fluorescence, with a fluorescence maximum at λ=537 nm and a quantum yield of 0.47 in the solid (powder) state. For compound 1, we observed a red shift of Δλ=72 nm and fluorescence enhancement in the solid state relative to that in THF. Compound 2 emitted bright‐blue fluorescence (λ=463 nm, Φ=0.36) in the solid state, which was slightly blue‐shifted relative to that in THF (λ=466 nm vs λ=482 nm) and appeared as a narrow peak with a full‐width‐at‐half‐maximum of only 39 nm. The strong fluorescence emission in high‐viscosity glycerol solution and in the solid state may be attributed to restriction of the rotation of the 7‐diethylamino group, which led to non‐radiative deactivation.
Nanomagnetically modified vitamin B3 (Fe3O4@Niacin): An efficient and reusable green biocatalyst for microwave‐assisted rapid synthesis of 2‐amino‐3‐cyanopyridines in aqueous medium
Authors: Afradi Mojgan , Pour Sjjad Abbasi , Dolat Maryam , Yazdani‐Elah‐Abadi Afshin
Published: October 2017

Superparamagnetic nanoparticles of modified vitamin B3 (Fe3O4@Niacin) represent a new, efficient and green biocatalyst for the one‐pot synthesis of 2‐amino‐3‐cyanopyridine derivatives via four‐component condensation reaction between aldehydes, ketones, malononitrile, and ammonium acetate under microwave irradiation in water. This new magnetic organocatalyst was easily isolated from the reaction mixture by magnetic decantation using an external magnet and reused at least six times without significant degradation in the activity. The catalyst was fully characterized by FT‐IR, XRD, SEM, VSM, UV–Vis, DLS and EDS. Excellent yield, very short reaction time (7–10 min), operational simplicity, easy work‐up procedure, avoidance of hazardous or toxic catalysts and organic solvents are the main advantages of this green methodology which makes it more economic than the other conventional methods.
Performance analysis of chemical flooding in fractured shale and tight reservoirs
Authors: Sheng James J.
Published: October 2017

To enhance the oil recovery in fractured shale and tight oil reservoirs, many efforts have been made to add surfactants in injection water and fracturing fluid. Most of the efforts were to conduct experiments to screen surfactants. To the best of our knowledge, there is no paper to provide numerical analysis of the surfactant performance in fractured shale and tight reservoirs. In particular, how the fracture network affects chemical flooding performance has not been addressed. This paper is to use numerical simulation approach to analyze the performance of chemical additives (alkali and surfactant) in fractured shale and tight rocks. The base simulation model is based on history‐matching an experiment. The effects of wettability alteration, interfacial tension (IFT), capillary pressure, and pressure gradients are investigated. To aid our understanding and interpret the results, the results from high‐permeability models are compared with shale and tight models. We found that if the rock is oil‐wet, it is very slow for a chemical to diffuse into the shale or tight matrix to alter wettability, so the oil recovery is not very sensitive to the value of capillary pressure. In shale and tight reservoirs, using surfactants to achieve ultralow IFT may not be effective, because the surfactant solution with ultra‐low IFT cannot enter the matrix and will break though producers, and oil in the matrix will be bypassed. And increasing the pressure gradient may not be effective because a high‐pressure gradient will aid breakthrough, instead of enhancing injected fluid invasion into the matrix.
Short Antimicrobial Peptides Exhibiting Antibacterial and Anti‐Inflammatory Activities Derived from the N‐Terminal Helix of Papiliocin
Authors: Jeon Dasom , Jacob Binu , Kwak Chulhee , Kim Yangmee
Published: October 2017

Papiliocin is a 37‐residue antimicrobial peptide, with Trp2 and Phe5 previously reported as key residues necessary for its antibacterial activity. This study determined the essential length of the N‐terminal fragment of papiliocin necessary to retain its biological activity. We designed and synthesized an array of seven peptides from the N‐terminal helix (PapN), with longest peptide with 22 residues and the shortest peptide consisting of the first 10 residues. The minimum inhibitory concentration (MIC) values and cytotoxicity measurement revealed that a PapN‐12mer containing a three‐turn, amphipathic helix was the shortest peptide exhibiting antibacterial activity without cytotoxicity. Additionally, PapN‐20mer peptide containing two isoleucines at the C‐terminus represented the shortest peptide exhibiting potent anti‐inflammatory activities by inhibiting nitric oxide production and inflammatory cytokine production in lipopolysaccharide‐stimulated mouse macrophage RAW264.7 cells. These results provided valuable insights into the design of short, potent peptide analogs of papiliocin.