bluuebunny/crossref_metadata_2025 huggingface dataset:
Mobilization of plant genetic resources from South and Southeast Asia
Authors: Loskutova N. P. , Ozerskaya T. M.
Published: April 2021

The article is devoted to the replenishment of the VIR collection with plant genetic resources from the territories of the Philippines, Burma, Laos and Vietnam as a result of plant explorations, seed requests and germplasm exchange. In total, four collecting missions were sent to this region in the late 1970s and 1980s. Through their efforts, 2668 germplasm samples were collected and delivered to the Institute. The most numerous were the accessions of grain legumes (916), followed by vegetables (835) and groat crops (653). In addition to direct collection, the Institute was constantly engaged in requesting plant germplasm. In the prewar period, from 1925 to 1941, 396 accessions of cereal, groat, grain legume, vegetable, industrial and fruit crops were received from Burma, Vietnam, French Indochina (Laos since 1949) and the Philippines. From 1946 to 2019, 7928 accessions were added, with the largest number shipped from Vietnam (7840). Such a huge number can be explained by the activities of the Soviet breeding stations in Lai Châu Province, Northern Vietnam, and near Ho Chi Minh City, Southern Vietnam, in the 1980s and early 1990s. It should be noted that significantly fewer wild species and crop wild relatives were mobilized from these countries than from India, Indonesia and Ceylon – about 100 spp., or 10,992 accessions. Altogether, collecting teams brought from the South Asian tropical center of crop origin 18,594 germplasm samples, most of which were groat crops (4521). The prewar seed requests yielded 3520 accessions, with 1022 representing tropical woody, ornamental and medicinal plants from botanical gardens. Requests for germplasm from 1946 to the present time resulted in adding 16,687 accessions to the collection, half of which were groat crops (rice, maize and sorghum). A total of 39,161 accessions were received from the region.
Assessment of potential winter hardiness in winter bread wheat cultivars and genotypes by analyzing autofluorescence in seedling tissues
Authors: Karkhardin I. V. , Konovalov A. A. , Goncharov N. P.
Published: April 2021

Background.Winter crops are the most productive component of agricultural biocenoses. In Russia, winter wheat suffers the greatest losses in winter, so a search for traits marking high or low winter hardiness in autumn-sown genotypes, including improved cultivars, is needed to assess their potential for overwintering. One of such markers of high winter hardiness is an increased lignin content in plant tissues. The terminal enzyme in the phenylpropanoid pathway of metabolism, wherein lignin components are formed, is cinnamyl-alcohol dehydrogenase (CAD, EC 1.1.1.195). In plants, the CAD enzyme is one of the links in the aromatic metabolism, which generates, in addition to lignin, a number of aromatic compounds, such as lignans, aromatic glycosides, etc. Many of these compounds, like lignin, contain chromophore groups and are capable of autofluorescence.

Correlations of the genotypes that incorporate CAD1-F with overwintering are studied in this work.

Materials and methods.The winter bread wheat cultivars ‘Zitnica’ (Yugoslavia) and ‘Novosibirskaya 9’ (ICG SB RAS, Russia), contrasting in winter hardiness and CAD isozyme spectra, their hybrids, and 28 improved winter cultivars developed in Krasnodar were selected for the study. Fluorescence analysis of 28 winter wheat cultivars was also performed. Correlation coefficients between fluorescence and frost tolerance were calculated using the results of the analysis of 7 most contrasting cultivars.

Conclusions. The tested winter bread wheat genotypes demonstrated the interplay between CAD1-F and successful overwintering: a correlation was found in the genotypes carrying the 00 CAD1-F allele with higher percentage of overwintered plants. This dependence was not observed in every season. The analysis of seedling sections for fluorescence can also be used for preliminary assessment of winter tolerance in winter bread wheat under laboratory conditions.
Prospects for the introduction of Symphytum asperuminto the Far North of the Russian Federation
Authors: Korelina V. A. , Batakova O. B.
Published: April 2021

Background.The choice of crops with greater adaptability to the environments of the Northern Region and higher yield of dry matter per hectare, rich in protein, essential amino acids, vitamins, sugars, carotene, and trace elements, would solve the problem of providing livestock with highquality feeds.

Materials and methods.The object of the study was rough comfrey (Symphytum asperumLepech.). The research was carried out in the experimental field of the N. Laverov Federal Center for Integrated Arctic Research in Kotlas from 2006 to 2019 using generally accepted techniques. The soils were sod-podzolic loams. Planting of S. asperumwas carried out with cuttings (4–5 pieces per 1 m2) in May 2006. The record plot area was 5 m2, the number of replications was three, and the arrangement of variants was regular.

The nutritional value of the introduced plant was compared with that of red clover (cv. ‘Prior’) in the biochemical laboratory in a NIR SCANNER 4250 infrared analyzer, calculated for 1 kg of dry matter.

Results.Successful introduction of rough comfrey (S. asperum) into the subarctic zone of the European North of Russia from its natural gene pool was assessed on the basis of a study of economically useful traits with the purpose of its possible utilization in agricultural production. This species was seen to pass through the entire cycle of ontogenesis, which is the evidence of a high degree of adaptation to the conditions of the region. The introduced species is characterized by high winter hardiness, good aftermath yield, early-spring regrowth, stable productivity, resistance to diseases and pests, and high nutritional value of the feed.
Results of studying wheatgrass (AgropyronGaertn.) accessions from the VIR global genetic resources collection in Yakutia
Authors: Koryakina V. M. , Kochegina A. A.
Published: April 2021

With the globally changing climate, researchers seek to use plants adapted to extreme environments in breeding and genetic programs. As a forage crop, the wheatgrass from the genus AgropyronGaertn. is most suitable for such purposes.

The area of temperature distribution for wheatgrass lies in the range from +42 (arid zone) to –60°C (Verkhoyansk). The use of different wheatgrass species as a crop for arid conditions is quite profoundly studied in the USA, Canada, Russia, and Kazakhstan. Genetic and breeding studies are underway in different countries. In Yakutia, with its extremely continental climate, wheatgrass has not yet been introduced as a crop, although it could play an important role in establishing a sustainable fodder reserve.

The aim of the work was to study and select promising breeding source material, identifying germplasm with the best agronomic traits. As a result of a two-year study of 19 accessions of different wheatgrass species from the collection of VIR, undertaken in 2018 and 2019 in the collection nursery in Central Yakutia, plant forms were selected that exceeded the average green biomass yield for two cuts: k-52382 (wild crested wheatgrass, Pavlodar Region, Kazakhstan) by 43%, and k-48705 (wild-growing Kerch wheatgrass) by 40%. Besides, wild wheatgrass accession k-52382 was identified for its dry matter yield (40.2% higher than the average) and for the total green and dry matter yield for the two cuts (212.7 g/plant).Accessions k-52440 (wild Siberian wheatgrass, Stavropol Territory) and k-51330 (crested wheatgrass, Chelyabinsk Province) were selected for their high seed yield (43.5 g/m² and 41.7 g/m², respectively). The content of crude and digestible protein was the highest in k-50857 (crested wheatgrass cv. ‘Ephraim’, USA) and k-50858 (Siberian wheatgrass cv. ‘Vavilov II’, USA): 14.6% and 99 g/kg of feed, and 14.2% and 96 g/kg of feed, respectively. Winter hardiness of 12 accessions turned out to be 100%, with 80% in another 7 accessions.
Complex biochemical characteristics of Coriandrum sativumL
Authors: Khmelinskaya T. V. , Smolenskaya A. E. , Solovyeva A. E.
Published: April 2021

Background. Coriandrum sativumL. is a valuable vegetable crop with early maturity and high nutritional benefits. Green biomass of coriander is rich in vitamins, especially ascorbic acid and carotene. The feasibility of using coriander as a natural food additive is due to its high antioxidant activity. The aim of this research was to study the biochemical composition of the green biomass in the accessions of C. sativumfrom the VIR global collection and identify promising accessions for use in breeding for quality.

Materials and methods.The green biomass of 67 coriander accessions from different countries maintained in the VIR collection served as the research material. The study was carried out according to the guidelines developed by VIR.

Results.As a result of the study, the feasibility of using C. sativumas a source of bioactive compounds was theoretically justified and experimentally confirmed, thus attesting to the prospects of coriander accessions from the VIR collection for quality-targeted breeding programs. New data were obtained on the biochemical composition of coriander green biomass. A factor determining such biochemical composition is the genotypic features of coriander associated with its origin. Biochemical parameters in coriander varied significantly depending on the origin of an accession. The highest variability was observed in the content of carotenes (CV 41%). The effect of an accession’s precocity was not confirmed. Sources for individual quality indicators were highlighted.

Conclusion. Accessions with an optimal component composition for a balanced human diet were identified and recommended for quality-oriented breeding, including the development of cultivars for health-friendly, curative and preventive nutrition. The selected accessions are of interest as source material for breeding programs and practical utilization.
Evaluation of naked oat accessions from the VIR collection for their qualitative characteristics in Kazakhstan
Authors: Abugalieva A. I. , Loskutov I. G. , Savin T. V. , Chudinov V. A.
Published: April 2021

Background.The grain of naked oat varieties has a unique biochemical composition (increased content of protein, starch, fat, and β-glucans) for the production of high-quality dietary food and feed. Relatively low adaptability restrains the spread of naked oat cultivars, but the demand for them has been increasing from year to year. Currently, only hulled oat cultivars are introduced into industrial cultivation in Kazakhstan, so the breeding trend aimed at the development of high-yielding naked oat cultivars may be regarded as a priority.

Materials and methods. Thirty-five accessions of naked oats (Avena  sativaL.  subsp. nudisativa(Husnot.) Rod. et Sold.) were selected from the germplasm collection of the N.I. Vavilov All-Russian Institute of Plant Genetic Resources (VIR) for their suitability for the conditions in Kazakhstan in terms of the growing season, drought resistance and grain productivity. The study was carried out in 2015–2017 in the fields of the Kazakh Research Institute of Agriculture and Crop Production (Almaty) and the Karabalyk Agricultural Experimental Station (Kostanay). Grain quality of naked oats was assessed by various methods according to a set of biochemical characters: the content of protein and its fractions, starch, amylose, fat and fatty acids, and β-glucans.

Results. The study of naked oat accessions from VIR in the environments of the southeastern Kazakhstan showed higher average values of protein content in grain than under the conditions in the north. As a result of the study, naked oat accessions with increased and stable indicators of the content of protein, starch, amylose, fat, individual fatty acids and β-glucans were identified for the conditions of the southeastern and northern regions of Kazakhstan. All selected accessions will be used in breeding programs of the Republic of Kazakhstan to develop high-yielding and high-quality naked oat cultivars.
Technological properties of grain and flour in bread wheat (Triticum aestivum L.) genotypes carrying two loci that determine the endosperm structure
Authors: Simonov A. V. , Pshenichnikova T. A.
Published: April 2021

Background.The end-use of the bread wheat grain depends on the endosperm properties determined by the alleles of the Pinaand Pinbgenes at the Halocus on chromosome 5D. The mealy (soft) endosperm is generated by the biosynthesis of puroindolines – complete proteins encoded by these genes. When milled, such grain breaks down into small starch granules covered with proteins. Mutations that disrupt the synthesis or structure of puroindolines determine the hardness and vitreousness of the grain. Earlier, we discovered a new locus for grain softness, Ha-Sp, introgressed from the diploid species Aegilops speltoidesTausch, which also determines the formation of the soft endosperm structure. By combining two active loci in one genotype, we produced a supersoft grain line (SSL). The aim of the present work was to verify the interaction of the two loci Haand HaSpin other wheat genotypes and evaluate the technological properties of grain and flour in comparison with the existing SSL line.

Materials and methods.The F3–F8 hybrids from crosses of the soft-grain spring cultivars ‘Golubka’ and ‘Lutescens 62’, carriers of the Halocus, with the introgressive line 84/98w, carrier of the Ha-Splocus, were used in the work. Grain from three field seasons was studied according to milling parameters and physical properties of flour and dough.

Results.At the early stages of selection (F3:4), the families with milling parameters typical of bread wheat were identified, as well as supersoft-grain families with a small flour particle size (9–10 μm) and low endosperm vitreousness (29–49%). Targeted selection made it possible to obtain lines similar to the SSL line in terms of milling performance and flour strength.

Conclusion.For the first time, a set of supersoft-grain lines with special properties of grain and flour was obtained on the genetic basis of three spring cultivars. They may be in demand for a wide range of end-uses, including both food and nonfood production purposes.
Diversity of high-molecular-weight glutenin subunits and evaluation of genetic similarities in spring bread wheats from different breeding centers
Authors: Utebayev M. U. , Bome N. A. , Zemtsova E. C. , Kradetskaya O. O. , Chilimova I. V.
Published: April 2021

Background.Glutenin is a storage protein in wheat seeds, important for the quality of bread prepared from wheat. Studying glutenin polymorphism can help to identify valuable genotypes and promising new breeding lines for further crossings. The aim of this study was to identify subunits of glutenin and determine alleles at the Glu-1loci in the spring bread wheat germplasm collection.

Materials and methods.A panel of 54 Russian and 76 Kazakh bread wheat germplasm accessions from various breeding centers was selected. Gliadin electrophoresis was carried out in a concentrating and separating polyacrylamide gel system following the Laemmli method. Glutenin subunits were identified according to the catalogue produced by Payne and Lawrence.

Results and discussion.At the Glu-A1 locus, two alleles, band c, were identified, with different frequencies of occurrence among studied wheat accessions. The Glu-A1ballele occurred more frequently than Glu-A1сin the studied germplasm from all breeding centers. Meanwhile, six alleles, а, b, c, d, fand g, were found at theGlu-B1 locus. The most frequently occurring Glu-B1с allele encoded two subunits (7+9). The third homologous gene, Glu-D1, had only two identified alleles, aand d, with various frequencies among the studied wheat accessions. Wheat germplasm of various origin had specific combinations of glutenin subunits, providing different scores of grain quality. For example, the combination of glutenin subunits, 2*, 7+9 and 5+10, provided the highest score (= 9) of grain quality. A single change in the Glu-1subunit composition, 2*, 7+9 and 2+12, caused a reduction in grain quality (= 7 score); and the combination of Null, 7and 5+10 was accompanied by the lowest (= 6) grain quality. The analysis showed that two loci, Glu-A1 and Glu-B1, induced significant differences between wheat accessions originated from Tyumen and Chelyabinsk, while the accessions from Chelyabinsk and East Kazakhstan differed significantly at the Glu-A1and Glu-D1loci.
The impact of temperature patterns during storage of Scots pine and Norway spruce seeds on their germination and fungal infection rates
Authors: Nikolaeva M. A. , Varentsova E. Yu. , Safina G. F.
Published: April 2021

Relevance of the study. One of the ways to maintain the genetic diversity of forest-forming species is to preserve highquality seed material ex situ. However, the relationship between the diversity of pathogenic mycobiota and the duration and methods of forest tree seed storage remains underexplored. The results of research into this problem can be used in forest seed production and forest phytopathology.

Materials and methods. For our study we used seeds ofРinus sylvestris L. and Picea abies (L.) Karst. of the orthodox type, harvested in the period of 1996–2011 and stored under different temperatures: +20°С, +4°С, –18°С, and in liquid nitrogen vapor (–182°С) since 2011. Prior to their storage, seed samples were dried to a moisture content of 4.2–4.4% and hermetically packed. Seed germination was tested before and after three, five and eight years of storage, following GOST 13056.6-97 standards. The level of seed infection and the composition of pathogenic fungi were assessed.

Results. After eight years of storage at +20°С, pine and spruce seed germination capacity decreased by 13–60%, depending on the year of harvesting. Seed storage at –18°С and –182°С allowed us to prevent seed infection and preserve seed viability. In most cases, the germination energy and germination capacity were negatively correlated with the level of seed infection. The diversity of pathogenic (mold) fungi on the surface of seeds was represented by ten genera; the most common were saprotrophs: Aspergillus P. Micheli, Penicillium Link, Rhizopus Ehrenb., Scopulariopsis Bainier.

Conclusion. At the present stage of research, the success of seed storage at low and ultralow temperatures was demonstrated. We recommend cryopreservation for the long-term storage of improved and valuable seeds.
Kur’ân-ı Kerîm Harfleri Bağlamında Bir İhtilaf Alanı (Lakap, Mahreç, Sıfat Eksenli Bir Değerlendirme)
Authors: KILIÇ Mustafa
Published: April 2021

Tecvid ilminin en önemli meselesi Kur’ân-ı Kerîm harfleridir. Zira harflerin düzgün telaffuz edilmesi, Kur’ân tilâvetinde hatadan korunmanın en temel şartıdır. Söz konusu gerçeklikten hareketle İslâm âlimle-ri Arap dilinde harflerin tasnifine, mahreçleri ve sıfatları konusuna ilk asırdan başlamak üzere her devirde özel bir önem vermişlerdir. Arap dilinde harflerle alakalı konular ele alındığında gündeme gelen mesele-lerden biri de onların lakapları meselesi olmuştur. Halîl b. Ahmed’in Kitâbü’l-‘Ayn isimli eserinde harflerin mahreçlerini gözeterek on tane lakap belirlemesiyle harflerin lakapları konusunun erken dönemde ortaya çıktığı gözlemlenmektedir. Harflerin lakapları, onların mahreçlerinden hareketle oluşturulmakla birlikte konunun, harflerin sıfatlarıyla da irtibatlı olduğu anlaşılmaktadır. Bu makalede harflerin lakapları mesele-sinin ortaya çıkışı, lakaplar konusunun eserlerde yer alma süreci, harfler için belirlenen lakapların neler olduğu, harflerin lakapları tamlamasıyla ne kastedildiği, harflerin lakaplarının bağlantılı olduğu diğer baş-lıklar, aynı harflere verilen lakapların âlimler arasında farklılık arz edip etmediği, harflerin lakapları konu-suna yer veren müelliflerin oranı, harflerin lakapları bağlamında öne sürülen eleştiriler gibi Arap dili, kı-raat ve tecvid ilimlerinde harflerin lakaplarıyla bağlantılı konular araştırılacaktır.
Penerapan Asuhan Keperawatan Jiwa Pada Ny. A Dengan Gangguan Sensori Persepsi : Halusinasi
Authors: Utami Bika , Tumanggor J Alex , Daeli May Thent Gustavian , Purba Winda Veratami , Silaban Yolanda Vega W. , Sianturi Yosi Meichi
Published: April 2021

Halusinasi adalah gangguan penerimaan pancaindra tanpa stimulasi eksternal (halusinasi pendengaran, penglihatan, pengecapan, penciuman, dan perabaan). Halusinasi merupakan salah satu gejala gangguan jiwa pada individu yang ditandai dengan perubahan sensori persepsi yaitu merasakan sensasi palsu berupa suara, penglihatan, pengecapan, perabaan atau penghidungan. Pasien merasakan stimulus yang sebenarnya tidak ada
The Phenomenon of Competitive Human Resources and How It Impacts Business Growth
Authors: Winatha Arvin
Published: April 2021

Increasingly tight business competition map of industry has been the main focus for everyone in the world, especially in the industry we call it as the Industry era 4.0 . The awareness of this competiton has made many business organizations in the world, including Indonesia busy preparing themselves, particularly those related to the development of human resources, to be ready to compete in this global era. The Fourth wave of industrial revolution is marked by the use of information technology, artificial intelligence, and automatic engines or vehicles that have been going on since years before.
Differential expression of marker of proliferation Ki-67 in cancers of the breast.
Authors: Mamoor Shahan
Published: April 2021

Breast cancer affects women at relatively high frequency (1). We mined published microarray datasets (2, 3) to determine in an unbiased fashion and at the systems level genes most differentially expressed in the primary tumors of patients with breast cancer. We report here significant differential expression of the gene encoding marker of proliferation Ki-67, MKI67, when comparing primary tumors of the breast to the tissue of origin, the normal breast. MKI67 was also differentially expressed in the tumor cells of patients with triple negative breast cancer. MKI67 mRNA was present at significantly higher quantities in tumors of the breast as compared to normal breast tissue. Analysis of human survival data revealed that expression of MKI67 in primary tumors of the breast was correlated with overall survival in patients with basal subtype cancer, demonstrating a relationship between correlation of primary tumor expression with overall survival based on molecular subtype. MKI67 may be of relevance to initiation, maintenance or progression of cancers of the female breast.
Companies in Indonesia in the vortex of global economic disruption
Authors: Chevonee Felisca
Published: April 2021

The best alternative for companies in Indonesia to survive in the midst of global economic uncertainty is by transforming their business and human resources, given that changes in business concepts are highly driven and patterned by advances in information technology that are exponentially increasing. The innovative steps of transformation, however, should refer to Good Corporate Governance, as an operational foundation and guarantee trust from stakeholders. The era of economic disruption requires companies in Indonesia to always generate new values in all aspects so that performance can increase and the companies are able to survive in the market by gaining positive profits.
Peningkatan Profit Melalui Daya Saing yang Berkualitas
Authors: Nurasia
Published: April 2021

Setiap perusahaan atau pelaku usaha harus memikirkan berbagai macam cara atau strategi untuk dapat mencapai tujuannya. Melalui daya saing yang berkualitas mampu meningkatkan profit atau keuntungan dari apa yang kita lakukan. Profit (laba) merupakan elemen atau bagian yang menjadi pusat perhatian karena angka laba diharapkan cukup untuk merepresentasi kinerja perusahaan secara keseluruhan. Dengan demikian, sang pelaku usaha harus memenuhi kebutuhan konsumen, perusahaan harus benar-benar memperhatikan produk mereka. Karena apabila apa yang diharapkan oleh konsumen terhadap produk yang ditawarkan sesuai dengan apa yang dinginkan. Maka konsep daya saing yang berkualitas harus diterapkan sehingga dapat meningkatkan profit atau keuntungan bagi perusahaan.
Journal Citation: “Companies in Indonesia in the Vortex of Global Economic Disruption”
Authors: Casta Amabel
Published: April 2021

Given that developments in business concepts are heavily influenced and patterned by rapidly growing advancements in information technology, the best option for Indonesian businesses to thrive in the face of global economic uncertainty is to transform their business and human capital. However, as an organizational framework and to ensure stakeholder confidence, the innovative transition measures should refer to Good Corporate Governance. Companies in Indonesia must constantly create new values in all facets of their operations in order to improve efficiency and succeed in the market by gaining positive profits in this era of economic disruption. Human resources management is also very important. This study is qualitative research with the interpretive paradigm, based on reality or the phenomenon that occurs. The findings were in the form of comprehensive analysis according to the primary and secondary data that the researchers have successfully explored.
pemecahan masalah pada pembelajaran matematika
Authors: NURWAHIDAH
Published: April 2021

Dalam memecahkan masalah memang sudah menjadi salah satu tujuan dalam pembelajaran, namun kemampuan peserta didik dalam hal ini sangat tergolong rendah. kemampuan pemecahan masalah pada matematika sangat diperlikan karena bukan hanya untuk mempermudah peserta didik dalam memecahkan masalah pada pembelajaran matematika akan tetapi juga pada pembelajaran lain. Pemecahan masalah adalah proses berpikir yang dilakukan oleh peserta didik dalam menyelesaikan masalah dalam pembelajaran dengan menggunakan keterampilan yang dimiliki oleh peserta didik itu sendiri. Tujuan pemecahan masalah pada pembelajaran matematika yaitu diharapkan untuk meningkatkan kemampuan metakognitif serta mendorong pola pikir peserta didik dalam memecahkan masalah dengan pengetahuan yang telah dimiliki sebelumnya. Dengan begitu peserta didik dapat berkompetisi dalam menyelesaikan permasalahan baik secara kelompok maupun individu.
MEDIA PEMBELAJARAN DALAM PENDIDIKAN MATEMATIKA
Authors: Hakim Muhammad Lutfil
Published: April 2021

Salah satu cara untuk membantu dalam proses belajar mengajar adalah media pembelajaran. Dengan adanya pembelajaran, baik pendidik maupun peserta didik dapat meningkatkan efesienitas dan efektifitas pada saat proses pembelajaran berlangsung. Peranan media pembelajaran sendiri sangat krusial di dalam proses pembelajaran bahkan pensil dan penggaris juga termasuk dalam media pembelajaran. Di zaman modern dengan kemajuan teknologi yang begitu pesat media pembelajaran tradisional mulai diambil alih perannya oleh media pembelajaran yang modern.
DIAGNOSTIK KESULITAN BELAJAR BELAJAR
Authors: Hardiana
Published: April 2021

jurnal terkait kesulitan belajar matematika dan bagaimana cara mengatasinya IAIM Sinjai
Differential expression of M-phase phosphoprotein 9 in cancers of the breast.
Authors: Mamoor Shahan
Published: April 2021

Breast cancer affects women at relatively high frequency (1). We mined published microarray datasets (2, 3) to determine in an unbiased fashion and at the systems level genes most differentially expressed in the primary tumors of patients with breast cancer. We report here significant differential expression of the gene encoding the M-phase phosphoprotein 9, MPHOSPH9, when comparing primary tumors of the breast to the tissue of origin, the normal breast. MPHOSPH9 was also differentially expressed in the tumor cells of patients with triple negative breast cancer. MPHOSPH9 mRNA was present at significantly higher quantities in tumors of the breast as compared to normal breast tissue. Analysis of human survival data revealed that expression of MPHOSPH9 in primary tumors of the breast was correlated with overall survival in patients with luminal A subtype cancer, demonstrating a relationship between correlation of primary tumor expression with overall survival based on molecular subtype. MPHOSPH9 may be of relevance to initiation, maintenance or progression of cancers of the female breast.
Metakognisi dalam pembelajaran matematika
Authors: ulandari Rika
Published: April 2021

Pada proses pembelajaran terkadang terdapat kesalahan konsep pada informasiyang diperoleh peserta didik yang telah disampaikan oleh guru. Terkait dengan haltersebut, metakognisi dapat memantau tahap berfikir peserta didik sehingga dapatmenjelaskan cara berpikir dan hasil berpikirnya. Dalam proses pembelajaran,metakognisi mempunyai peran penting khususnya dalam pemecahan masalahmatematika. Metakognisi sebagai proses seseorang berpikir tentang berpikir dalamrangka membangun strategi untuk memecahkan masalah. Metakognisi dapat dilihat dariaktivitas seperti merencanakan bagaimana pendekatan yang diberikan dalam tugas-tugaspembelajaran, memonitor kemampuan dan mengevaluasi rencana rencana dalam rangkamelaksanakan tugas. Beberapa langakah untuk mengembangkan metakognisidiantaranya: mengidentifikasi “apa yang kau ketahui”, berbicara tentang berpikir,membuat jurnal berpikir, membuat perencanaan dan regulasi diri, melaporkan kembaliproses berpikir, dan evaluasi diri. Semua siswa telah menggunakan strategi metakognisidalam pembelajaran matematika, dengan kategori yang bervariasi dan secara umumberkategori jarang. Strategi yang paling tinggi atau sering digunakan oleh siswa secaraumum adalah tutor sebaya, dan yang paling jarang digunakan adalah Evaluating the wayof thinking and acting. Pengembangan kemampuan metakognisi siswa dalampembelajaran matematika dapat dilakukan melalui pembiasaan berpikir, ini perludilakukan terus menerus dan berkelanjutan untuk selanjutnya diteliti efektivitasnya. Haldemikian tidak selalu mudah dilakukan. Proses penemuan konsep tidak serta-mertadapat dilakukan siswa. Demikian juga aktivitas metakognisi siswa juga tidak selaluterjadi dengan mudah. Oleh karena itu bimbingan guru merupakan hal yang esensial.Kata kunci : Metakognisi, Strategi Metakognisi, Pengembangan Metakognisi DalamPembelajaran Matematika.
PENERAPAN “self concept” REMAJA PADA KONDISI PANDEMI COVID-19
Authors: Tampubolon Kristina N
Published: April 2021

ABSTRAKRemaja adalah asset Agama, bangsa dan Negara baik dalam peran sebagai individu maupun sebagai anggota masyarakat dan warga negara. Masa remaja merupakan sebuah periode perkembangan di mana individu haus untuk berpetualang, menyukai risiko, serta menginginkan sesuatu hal yang baru dan menantang agar secara alamiah dapat mencapai kondisi yang bergejolak. Oleh karena itu, pengembangan diri secara menyeluruh pada semua aspek kehidupan, baik fisik maupun psikologis sangatlah diperlukan.Pengembangan ketiga aspek (intelektual, social –emosional dan life skill) remaja baik dalam lingkup pendidikan informal, formal, non formal harus didasari dengan pengembangan spiritual sebagai landasan mencapai tujuan hidup yang hakiki dan menumbuhkan konsep positif dalam diri setiap remaja. Konsep diri sebagai suatu obyek yang timbul di dalam interaksi sosial sebagai suatu hasil perkembangan dari perhatian individu tersebut mengenai bagaimana orang lain bereaksi kepadanya. Banyak permasalahan yang timbul akibat dari rendahnya kontrol diri. Sesuai dengan penjelasan Bhave & Saini mengatakan manusia perlu mempelajari bagaimana cara mereka mengendalikan emosinya agar beradaptasi dengan baik.Oleh karena itu,dalam tulisan ini kita akan membahas pentingnya konsep diri setiap remaja.
Differential expression of protein phosphatase 2A activator in cancers of the breast.
Authors: Mamoor Shahan
Published: April 2021

Breast cancer affects women at relatively high frequency (1). We mined published microarray datasets (2, 3) to determine in an unbiased fashion and at the systems level genes most differentially expressed in the primary tumors of patients with breast cancer. We report here significant differential expression of the gene encoding protein phosphatase 2A activator, PPP2R4, also known as PTPA (protein phosphatase 2 phosphatase activator) when comparing primary tumors of the breast to the tissue of origin, the normal breast. PPP2R4 mRNA was present at significantly higher quantities in tumors of the breast as compared to normal breast tissue. Analysis of human survival data revealed that expression of PPP2R4 in primary tumors of the breast was correlated with recurrence-free survival in patients with basal and luminal B type cancers, but in a contrary manner, demonstrating a complex relationship between correlation of primary tumor expression with recurrence-free survival based on molecular subtype. PPP2R4 may be of relevance to initiation, maintenance or progression of cancers of the female breast.
Studi Kasus: Asuhan Keperawatan Jiwa Pada Ny.Y Dengan Gangguan Persepsi Sensori: Halusinasi Pendengaran
Authors: Hamdi Teuku
Published: April 2021

Standar Asuhan Keperawatan mencakup penerapan strategi pelaksanaan halusinasi. Strategi pelaksanaan pada pasien halusinasi mencakup kegiatan mengenal halusinasi, mengajarkan pasien menolak halusinasinya, minum obat dengan teratur, bercakap-cakap dengan orang lain saat halusinasi muncul, serta melakukan aktivitas terjadwal untuk mencegah halusinasi
UTS ESDM
Authors: n hafizh nurwala
Published: April 2021

Tugas sitasi UTS ESDM
The Energy Spectral Density of the Mertens Function
Authors: Cox Darrell , Sultanow Eldar , Ghosh Sourangshu
Published: April 2021

The Mertens function is the summatory Mobius function but the Mertens function can be generated recursively without using this definition. This recursive definition is the basis of autocorrelations that can be done on sequences of Mertens function values. Fourier transforms of the autocorrelations result in the energy spectral density. A likely upper bound of the absolute value of the Mertens function is determined.
Differential expression of KIAA0101 in cancers of the breast.
Authors: Mamoor Shahan
Published: April 2021

Breast cancer affects women at relatively high frequency (1). We mined published microarray datasets (2, 3) to determine in an unbiased fashion and at the systems level genes most differentially expressed in the primary tumors of patients with breast cancer. We report here significant differential expression of the gene encoding KIAA0101 when comparing primary tumors of the breast to the tissue of origin, the normal breast. KIAA0101 was also differentially expressed in the tumor cells of patients with triple negative breast cancer. KIAA0101 mRNA was present at significantly higher quantities in tumors of the breast as compared to normal breast tissue. Analysis of human survival data revealed that expression of KIAA0101 in primary tumors of the breast was correlated with distant metastasis-free survival in patients with HER2+ and luminal A subtype cancer, but in a contrary manner, demonstrating a complex relationship between correlation of primary tumor expression with overall survival based on molecular subtype. KIAA0101 may be of relevance to initiation, maintenance or progression of cancers of the female breast.
Sign of the Mertens function
Authors: Cox Darrell , Ghosh Sourangshu , Sultanow Eldar
Published: April 2021

Lehman proved that the sum of certain Mertens function values is 1. Functions involving the sum of the signs of these Mertens function values are considered here. Specifically, the upper bounds of these functions involving the number of Mertens function values equal to zero are determined. Franel and Landau derived an arithmetic statement involving the Farey sequence that is equivalent to the Riemann hypothesis. Since there is a relationship between the Mertens function and the Riemann hypothesis, there should be a relationship between the Mertens function and the Farey sequence. Functions of subsets of the fractions in Farey sequences that are analogous to the Mertens function are introduced. Results analogous to Lehman’s theorem are the defining property of these functions. A relationship between the Farey sequence and the Riemann hypothesis other than the Franel-Landau theorem is postulated.
Differential expression of ZW10 interacting kinetochore protein in cancers of the breast.
Authors: Mamoor Shahan
Published: April 2021

Breast cancer affects women at relatively high frequency (1). We mined published microarray datasets (2, 3) to determine in an unbiased fashion and at the systems level genes most differentially expressed in the primary tumors of patients with breast cancer. We report here significant differential expression of the gene encoding the ZW10 interacting kinetochore protein, ZWINT, when comparing primary tumors of the breast to the tissue of origin, the normal breast. ZWINT was also differentially expressed in the tumor cells of patients with triple negative breast cancer. ZWINT mRNA was present at significantly higher quantities in tumors of the breast as compared to normal breast tissue. Analysis of human survival data revealed that expression of ZWINT in primary tumors of the breast was correlated with overall survival in patients with basal and luminal A subtype cancer, but in a contrary manner, demonstrating a complex relationship between correlation of primary tumor expression with overall survival based on molecular subtype. ZWINT may be of relevance to initiation, maintenance or progression of cancers of the female breast.
Holographic surface and focusing
Authors: Kuyukov Vitaly
Published: April 2021

Holographic surface and focusing
Prospek Implementasi Reforma Agraria di Indonesia Setelah Terbitnya Peraturan Presiden Nomor 86 Tahun 2018
Authors: Nurrokhman Arsan
Published: April 2021

Tulisan ini bertujuan membawa studi atas Undang-undang Pokok Agraria (UUPA) ke arah yang lebih empirik dengan menggunakan teori-teori implementasi kebijakan publik, seperti yang dikenalkan Grindle (1980) tentang variabel konten dan konteks kebijakan. Jugateori para peneliti implementasi yang kritis yang menggunakan perspektif bottom-up dan menyoroti tindakan birokrat pelaksana. Penelitian menggunakan metode kualitatif melalui studi literatur dan fokus pada kebijakan eksekutif, tindakan birokrat dan serta konteks yang melingkupinya. Penelitian menemukan bahwa kebijakan eksekutif dengan terbitnya Peraturan Presiden RepublikIndonesia Nomor 86 Tahun 2018 justeru tidak selaras dengan beberapa ketentuan UUPA. Peraturan presiden tersebut memiliki paradoks, ingin mengakomodir banyak variabel tetapi mengalami kebingungan atas tujuan utama reforma agraria. Sebagai kebijakan yang relatif top down, implementasiUUPA sebenarnya memerlukan adanya aktor yang dominan. Namun tindakan birokrat pelaksana (street level bureaucrat) telah lama mereduksi tujuan undangundang menjadi sekedar tindakan legalisasi terhadap pembukuan transaksi atas tanah yang berjalan sesuai mekanisme pasar. Kini, semakin banyaknya penduduk Indonesia yang tinggal di wilayah perkotaan membuat isu tentangtanah lebih kompleks, terkait dengan alih fungsi lahan dan berbagai tantanganpembangunan berkelanjutan. Berbagai kondisi tersebut membuat prospek implementasi reforma agraria di Indonesia setelah terbitnya Peraturan Presiden 86/2018 masih belum menggembirakan. Masih diperlukan kebijakan yang mengakomodir misi utama UUPA dan perkembangan perkotaan.
Differential expression of the phosphorylase kinase catalytic subunit gamma 2 in cancers of the breast.
Authors: Mamoor Shahan
Published: April 2021

Breast cancer affects women at relatively high frequency (1). We mined published microarray datasets (2, 3) to determine in an unbiased fashion and at the systems level genes most differentially expressed in the primary tumors of patients with breast cancer. We report here significant differential expression of the gene encoding the phosphorylase kinase catalytic subunit gamma 2, PHKG2, when comparing primary tumors of the breast to the tissue of origin, the normal breast. PHKG2 mRNA was present at significantly higher quantities in tumors of the breast as compared to normal breast tissue. Analysis of human survival data revealed that expression of PHKG2 in primary tumors of the breast was correlated with recurrence-free survival in patients with luminal A and luminal B type cancers, demonstrating a relationship between correlation of primary tumor expression with recurrence-free survival based on molecular subtype. PHKG2 may be of relevance to initiation, maintenance or progression of cancers of the female breast.
Validitas Survei Kepuasan Masyarakat Online Terhadap Pelayanan Pertanahan Tahun 2018
Authors: Nurrokhman Arsan
Published: April 2021

Tujuan utama penelitian ini adalah untuk mengetahui validitas hasil Survei Kepuasan Masyarakat Online terhadap PelayananPertanahan yang dilaksanakan Pusat Penelitian dan Pengembangan Kementerian Agraria dan Tata Ruang/Badan PertanahanNasional pada tahun 2018. Metode yang digunakan adalah analisis kronologi terhadap stempel waktu (timestamp) sebagaibagian dari metadata yang terbuat secara otomatis saat responden mengirimkan isian survei. Penelitian menemukan bahwaterjadi banyak akumulasi pengisian survei dalam satu hari secara berurutan dengan selisih waktu yang pendek (rata-rata2 menit) di setiap kantor pertanahan. Patut diduga bahwa sebagian besar survei diisi oleh satu atau beberapa orang yangditugaskan secara khusus. Waktu yang berurutan, jumlah responden yang banyak dalam satu hari, identitas yang mirip,penilaian yang hampir seragam dan saran yang sama atau kosong dalam jumlah ribuan, membuat hasil survei kepuasansecara online diragukan validitasnya. Survei kepuasan masyarakat secara online masih memerlukan mekanisme khususuntuk mengontrol kualitasnya. Selain survei langsung ke lapangan, analisis terhadap metadata bisa menjadi alternatif kontrolkualitas tersebut dan rintisan ke penggunaan analisis big data yang lebih kompleks.
Studi Kasus: Asuhan Keperawatan Jiwa Pada Ny. A Dengan Masalah Halusinasi Penglihatan
Authors: Purba Winda Veratami
Published: April 2021

Halusinasi merupakan keadaan seseorang mengalami perubahan dalam pola dan jumlah stimulasi yang diprakarsai secara internal atau eksternal disekitar dengan pengurangan berlebihan, distorsi, atau kelainan berespon terhadap setiap stimulasi
A call to accompany pre-registration with means to valuable and effective exploration
Authors: Höfler Michael , Scherbaum Stefan , Kanske Philipp , Miller Robert
Published: April 2021

Harking and p-hacking are considered as main causes of the replication crisis, and pre-registration of hypotheses and analyses is regarded as the best countermeasure so far. However, the pressure to produce purportedly confirming results through hidden exploration largely resists. While some pre-registration advocates encourage the alternative of honest and comprehensive explorative research, others accuse pre-registration of harming exploration. We argue that researchers must be equipped with competencies on valuable exploration if pre-registration is to become mainstream and exploration is to be freed from its narrowed and flawed purpose. We discuss what valuable exploration should be: honest, as full as necessary (especially in new research domains) and as efficient as possible (resulting in only few and presumably true new hypotheses). After discussions on methods for filtering explorative results and pre-registration we end with a short research agenda on exploration and proposals for implementation to stakeholders (peer-reviewers, journal editors and funding agencies) who have the means both to enforce pre-registration and to provide room for valuable exploration. For example, we propose that yet a study abstract must contain separated lists of confirmatory results and new hypotheses obtained from exploration.
The Pause-then-Cancel model of human action stopping: theoretical considerations and empirical evidence
Authors: Diesburg Darcy A , Wessel Jan
Published: April 2021

The study of human action stopping has been dominated by two controversial debates. First, the contributions (and neural signatures) of attentional orienting and motor inhibition to the stopping process are near-impossible to disentangle. Second, the timing of purportedly inhibitory brain activity after to stop-signals has called into question which neural signatures actually contribute to stopping. Here, we propose that a two-stage model of stopping in rodents – proposed by Schmidt and Berke (2017) – may resolve these controversies. In translating this model to humans, we first argue that attentional orienting and motor inhibition are inseparable because orienting (to stop-signals and other salient events) automatically invokes broad motor inhibition, reflecting a fast-acting, ubiquitous Pause process. We then argue that inhibitory signatures after stop-signals differ in latency because they map onto different phases of this two-stage model: the global Pause and a slower Cancel process, which is specific to stop-signals. We formulate the model, discuss recent supporting evidence in humans, and interpret existing data within its context.
PEMBINAAN KOPERASI, USAHA KECIL DAN MENENGAH INDONESIA
Authors: Juliman
Published: April 2021

Sejak diberlakukannnya Otonomi daerah, maka sitem pelaksanaan yang berlaku di Indonesai berubah menjadi yang tadinya sentrlistik kearah dimana sistem pemerintahan di berbagai tngkatan seperti tingkat Provinsi,Kabupaten/Kota dan Desa, wajib mengurus dan mengembanka arah pembangunan oleh pemerintahan sendiri untuk sepenuhnya kesejahteraa publik yang dilaksanakan bisah dari wilayah lokal sampai dengan gobal. Dengan memanfaatkan fotensi-fotensi yang ada pada kekuatan pemerintahan lokal. Untuk pelaksanaan kemandirian pembangunan tersebut perlu didukung oleh organisasi yang handal, yang bergandengan dengan pemerintan, Badan Usaha Milik Desa (BumDes) , Unitunit keuangan Mikro (UKM) dan usasa-Usaha Masyarakat yang besinergi membangun Pemerintahan di berbagai tingkatan di indonesia. penulis menerbitkan buku ini adalah untuk menyalurkan minat pemanfaatan koperasi yang masih mempuyai kekuatan hokum yang dilindungi UNDANG-UNDANG REPUBLIK INDONESIA. NOMOR 25 TAHUN 1992. TENTANG. P E R K O P E R A S I A N. dan masih menjadi urusan Negara melalu Dinas Perindustrian,perdagangan dan Koperasi(DISPRINDAKKOP). dan buku yang masih sangat sederhana ini muda-mudanan bermanfaat bagi Mahasiswa, pelaku-pelaku usaha mikro, dan dapat menguatkan usaha-usasa yang dibngunan oleh pemerintahan seperti perusahaan Daerah dan BUMDES.untuk ditingkat desa. Selain penguatan-penguatan penggunaan dana yang bersumber dari pemerintah pusat.Untuk menerbitkan buku tentang koperasi ini. Perlu diketahui bahwa permasalahan yang timbul pada saat ini yang diberitakan dari berbagai sumber media menyatakan bahwa jumlah koperasi semakin menurun dan jumlah yang tidak aktif juga semakin menurun. Untuk itu menurut hemat penulis perlu perbaikan-perbaikan pemahan maupaun praktek kerja pada lembaga kopersi indonesia.
A review of in-situ testing of rock mechanical parameters in hydropower projects of Nepal
Authors: Nepal Kaustubh Mani
Published: April 2021

In-situ testing of rock mechanical parameters is essential for rock mass characterisation. The rock mass characterisation is important in design and construction of underground works forming major component of Hydropower projects. The major civil structures of most of the hydropower projects planned in Nepal have to be founded on complex rock formations on fragile geological environments. In-situ rock mechanics tests carried out at various hydropower projects sites are described and the findings are summarised.