bluuebunny/crossref_metadata_2025 huggingface dataset:
Efeito de substratos isolados e em combinação no crescimento de mudas de morangueiro
Authors: PIROLLI B. , LIMA J. M. , DUTRA B. R. , JUNIOR E. S. C. , ZIMMERMANN C. M. , BALDISSERA S. , CHASSOT T.
Published: December 2021

No cultivo do morangueiro o uso de mudas de qualidade representa a obtenção de plantas mais responsivas as práticas de manejo adotados ao longo do cultivo, mais produtivas e de melhor estado fitossanitário. A produção de mudas ocorre a partir do enraizamento de estolões, podendo ser produzidas mudas de raiz nua ou de torrão. Neste último caso, o substrato é fundamental para o bom desenvolvimento das plantas, gerando mudas com adequado enraizamento e elevado acúmulo de reservas na coroa e na raiz. Este trabalho teve o objetivo de analisar o crescimento de mudas de morangueiro cultivar Pircinque cultivados nos substratos de casca de arroz e Pindstrup®, isolados ou combinados em diferentes proporções. Para tanto, foi conduzido um experimento em casa de vegetação com os seguintes tratamentos: T1) 100% casca de arroz; T2) 75% casca de arroz e 25 % Pindstrup®; T3) 50% casca de arroz e 50% Pindstrup®; T4) 25% casca de arroz e 75% Pindstrup® e T5) 100% Pindstrup®. Foram avaliados os atributos de diâmetro de coroa (mm), número (und), comprimento (cm) e massa fresca de raiz (g) aos 14, 21 e 28 dias após a implantação do experimento. Os resultados obtidos demostraram que a combinação de 25% de casca de arroz e 75% de Pindstrup® possibilitou uma proporção mais adequada entre os substratos, pois, de modo geral, a mistura apresentou os melhores resultados considerando as variáveis analisadas, não diferindo estatisticamente, no entanto, do substrato com 75% casca de arroz e 25 % Pindstrup® para o atributo de comprimento de raiz.
Caracterização físico-química de requeijão cremoso com polpa de frutas
Authors: ALVES A. F. , SILVEIRA M. L. R. , CIROLINI A. , ROSA V. P.
Published: December 2021

Produto típico do Brasil, o requeijão cremoso é o mais consumido no país quando comparado aos outros queijos fundidos. Através desse grande consumo novos mercados do produto com a adição de novos ingredientes em sua composição ganham destaque e espaço. Devido à importância do requeijão cremoso no mercado brasileiro este trabalho teve como objetivo desenvolver e caracterizar quanto aos seus parâmetros físico-químicos o requeijão cremoso doce com adição de polpas de frutas. A partir da elaboração base do requeijão foram desenvolvidas três formulações com 5% de polpa nos sabores morango, pêssego e coco. Foram realizadas análises físico-químicas em triplicata para determinar a acidez titulável, pH, umidade, cinzas totais, proteínas e gordura. As amostras diferiram significativamente todos os parâmetros analisados, com exceção do teor de gordura, onde não houve diferença significativa entre a amostra de requeijão com sabor de morango e requeijão com sabor de pêssego. O requeijão cremoso com adição de polpa de morango, pêssego e coco apresentaram valores satisfatórios e de acordo com a legislação e literatura, sendo um possível potencial viável na contribuição do desenvolvimento de novos produtos lácteos.
Efeitos da COVID-19 sobre a produção e comercialização de ovos de galinha em Boa Vista-RR
Authors: UMIGI R. T. , COSTA G. C. O. , PINHEIRO M. L. , SOARES I. L.
Published: December 2021

O SARS-CoV-2, causador da COVID-19, rapidamente se espalhou da cidade de Wuhan (China) para diversos países, causando perdas humanas e econômicas. Um dos setores afetados pela pandemia causada por esse vírus foi a avicultura de postura e, mesmo com a alta dos preços das proteínas, o ovo vem se destacando em meio às carnes. Neste trabalho, analisou-se o efeito da COVID-19 sobre a produção e comercialização de ovos de galinha que, mesmo com a alta dos preços das proteínas, vem se destacando em meio às carnes. Foram elaborados questionários direcionados aos proprietários de granjas, donos/gerentes de supermercados e consumidores no município de Boa Vista - RR. Com as informações coletadas, constatou-se que os grandes produtores estão enfrentando problemas relacionados à alta dos insumos e à redução do lucro, embora consigam manter a quantidade de aves alojadas, enquanto os pequenos produtores, além dos problemas mencionados, descartam as aves para diminuir custo da produção. Por outro lado, os donos de supermercados, mesmo com a alta no custo dos ovos, passam incólumes aos problemas no abastecimento, sem que tenham de aumentar os estoques de ovos nas prateleiras, já que a demanda manteve-se alta. Segundo mostram os dados, os consumidores aumentaram a procura por ovos devido aos benefícios à saúde e, também, à maior alta dos preços das carnes. Desse modo, os entrevistados mostraram-se otimistas com a melhora da economia nacional e internacional após a vacinação em massa, tendo como perspectiva a diminuição do preço dos produtos, a fim de continuarem a consumir no mesmo ritmo que no período da pandemia.
Efeitos dos ácidos graxos trans na saúde
Authors: SOUSA T. F. , KUS-YAMASHITA M. M. M.
Published: December 2021

O ser humano sempre consumiu alimentos que continham ácidos graxos trans. No passado as fontes eram apenas as carnes, leite e produtos derivados de animais ruminantes, porém a partir da industrialização dos alimentos, em especial com o desenvolvimento da hidrogenação parcial dos óleos vegetais e a mudança nos padrões alimentares, seu consumo teve um aumento. Ácidos graxos trans causam diversos efeitos no organismo, sendo fatores de risco nas doenças cardiovasculares, na resposta inflamatória sistêmica; na disfunção endotelial; na resistência à insulina e na obesidade. Este trabalho teve como objetivo verificar o efeito dos ácidos graxos trans na saúde quanto a sua origem industrial e biológica. O consumo de ácidos graxos trans de origem industrial traz resultados deletérios à saúde humana, pois compõem a maior parte dos ácidos graxos trans presentes nos alimentos. Entretanto, em relação aos ácidos graxos trans de origem dos animais ruminantes, ainda há controvérsias quanto aos seus possíveis danos ao organismo, embora seu impacto deva ser menor do que dos ácidos graxos trans industriais, devido a sua baixa concentração nos produtos. Enquanto alguns estudos não encontraram nenhuma associação significativa do seu consumo com o aumento de doenças coronarianas, outros obtiveram resultados semelhantes aos dos ácidos graxos trans de origem industrial quando analisados os níveis de lipoproteínas plasmáticas.
Qualidade físico-química, microbiológica e sensorial de sorvete sabor cajá com substituição do açúcar por mel
Authors: NOGUEIRA L. P. S. , MEIRELES B. R. L. A. , ABREU D. K. P. , SILVA R. S. , NETO M. S. M. , ARAÚJO M. A. , MASCARENHAS N. M. H.
Published: December 2021

Consumidos mundialmente os sorvetes são produtos alimentícios obtidos a partir de uma emulsão de gorduras e proteínas, com ou sem adição de outros ingredientes e substâncias, ou de uma mistura de água, açúcares e outros ingredientes. O mel é um alimento biológico de grande valor nutricional e o cajá é um fruto extremamente aromático e rico em carotenoides. Diante do exposto, o presente trabalho tem como objetivo elaborar e caracterizar uma receita de sorvete artesanal com polpa de cajá, substituindo o açúcar utilizado na formulação padrão por mel. O experimento foi executado nos laboratórios do Centro Vocacional Tecnológico, da Universidade Federal de Campina Grande, Campus Pombal-PB. Foram elaboradas 3 formulações A1, A2 e A3, contendo substituição total ou parcial do açúcar por mel, variando entre 0, 50 e 100%, respectivamente. Os resultados foram avaliados pela ANOVA e as médias comparadas pelo teste de Tukey, considerando um nível de significância de 5% por meio do programa estatístico ASSISTAT versão 7.7. Verificou-se de acordo com os resultados microbiológicos que as amostras estavam aptas ao consumo humano. Para a análise sensorial na aceitação global, a formulação controle e a com substituição parcial do mel foram as que apresentaram melhores resultados, porém as três formulações não diferenciaram entre si. Nos valores de sólidos solúveis a amostra A1 apresentou valor superior se comparado com as demais formulações, muito provável devido a utilização somente do açúcar na sua elaboração. Nota-se que a substituição total do açúcar pelo mel de abelha neste tipo de produto torna-se uma alternativa viável de comercialização, trazendo um produto com um maior potencial nutritivo.
Almidón de camote: Modificaciones enzimáticas, físicas y químicas
Authors: Ochoa-Martínez Luz Araceli , Luna Solís Héctor Alejandro , Bermúdez Quiñones Gabriela
Published: December 2021

El almidón es el principal carbohidrato de reserva en productos vegetales y es ampliamente utilizado en la industria alimentaria. El camote es una fuente importante de almidón, ya que forma parte de su composición química en el rango de 50 - 80%. Sin embargo, en su forma nativa carece de propiedades que lo conviertan es un material ideal con potencial para aplicaciones en productos alimenticios. Por esto, con la finalidad de subsanar tal desventaja se recurre a procesos de modificación que permitan cambiar sus propiedades fisicoquímicas como la cristalinidad, viscosidad, tamaño de gránulo, temperatura de gelatinización, retrogradación, solubilidad, poder de hinchamiento, etc. Las modificaciones del almidón se centran en tres tipos de métodos; los enzimáticos (altamente eficientes), los físicos (diversos y económicos) y los químicos (selectivos). Cada vez resulta de mayor interés probar métodos de modificación en nuevas fuentes de almidón y debido a la alta producción de camote a nivel mundial, es importante mostrar los contrastes de los diferentes métodos utilizados. Por lo tanto, el objetivo de esta revisión es mostrar los estudios realizados para la modificación de almidón de camote y su efecto sobre las propiedades fisicoquímicas.
DOI: https://doi.org/10.54167/tecnociencia.v15i3.854
Neutrosophic Bi-topological Group
Authors:   Department of Mathematics, College of Science, Al-Furat University, Deir-ez-Zor, Syria, Al-Hamido Riad K. Al
Published: December 2021

Neutrosophic topological groups are neutrosophic groups in an algebraic sense together with neutrosophic continuous group operations. In this article, we have presented neutrosophic bi-topological groups with illustrative examples. We have also defined eight new models of neutrosophic bi-topological groups. Neutrosophic bi-topological group that depends on two neutrosophic topologies group is more general than the neutrosophic topological group. Finally, Some basic properties of neutrosophic bi-topological groups were studied.
Etymologisches im Lexicon romontsch cumparativ (LRC) (II)
Authors: Eichenhofer Wolfgang
Published: December 2021

As we have seen, the LRC is neither useful as a reference work nor as a teaching tool: it contains grammatical, morphological, semantic, etymological and struc-tural problems in a way that the reader has often to deal with misleading and wrong entries instead of finding advice in case of a linguistic doubt. The author often etymologises unsystematically, unscientifically and sometimes even tritely. This dictionary paints an unreal portrait of the Romontsch-Sursilvan language, an image that it is not worth to take seriously.
Dimensioni e dinamiche dei flussi migratori da Livinallongo/Fodom e da Colle Santa Lucia/Col nel corso del Novecento
Authors: Palla Luciana
Published: December 2021

This essay compares the migration from Livinallongo/Fodom and Colle Santa Lucia/Col, which were Ladin villages belonging to Austria until World War I, with the migration from the villages situated in the Alto Agordino, which be-longed to the neighbouring Kingdom of Italy. The research goes on until the 1980s, highlighting similarities and differences between the two areas, which have not only a different political history but also a dissimilar socio-economic and identity history. An element that has greatly influenced both, the quantity and type of emigration, is the model of inheritance of ownership that charac-terised the two areas, and which was very important before the tourism boom. In Fodom and Col there was the custom of undivided ownership according to Germanic law, while in the villages which had belonged to the Venetian Republic there was in force the Latin inheritance law, according to which the ownership was divided equally between the heirs, but did not allow any of them to live on the sole income from land ownership; this generated a temporary or permanent mass departure from the mountains. In Col and Fodom the departure of adults was more limited, however the emigration of minors was extremely widespread, especially towards Val Pusteria and Val Gardena, a sad phenomenon documen-ted through life testimonies.
“Wir wollen hoffen, dass es nicht so lange dauert…”
Authors: Rampold Reinhard
Published: December 2021

While the major events of the First World War were scientifically examined early on, the “everyday stories” associated with the war received little attention for decades. It is only in recent years that this aspect has been recognised as an inte-gral part of history and has also been the subject of academic research in Tyrol and Trentino. Luckily, an extensive collection of field postcards and field letters from Felix, Candidus and Albin Crepaz has been preserved. They were deployed as soldiers on Col di Lana and the Siefsattel in the immediate vicinity of their hometown Lasta, and experienced the impact of the war on their homeland and their relatives at first hand. The preserved documents – even though the letters of reply are missing – give a deep insight into the psychological and physical problems of an ordinary soldier, as well as the concern for his relatives and neighbours, and are thus an important evidence of the everyday history of Tyrol during the First World War.
Sistematización de una experiencia pedagógica en el aula. El diálogo de saberes y la interculturalidad como pilares en la formación de líderes y sujetos
Authors: Castaño Castaño Mónica María , García García Lady Jhoanna , Echeverría Reina Alberto José , Becerra Ocampo Ana María , Ocampo Marín Henry Alonso
Published: December 2021

En el presente artículo se presenta el reto de pensar el proceso de formación de líderes y sujetos mediante el diálogo de saberes. En este sentido, se reflexiona una experiencia docente, desde la cultura e identidad de los individuos en formación. Se piensa sobre sus conocimientos, sentimientos y acciones y se propone el sentido que debe cobrar la educación desde la sistematización de una experiencia profesoral como un proceso de reflexión e interpretación crítica y autocrítica sobre la práctica en el aula.
Spatial and temporal variation of surface air temperature at different altitude zone in recent 30 years over Nepal
Authors: NAYAVA JANAK LAL , ADHIKARY SUNIL , BAJRACHARYA OM RATNA
Published: December 2021

This paper investigates long term (30 yrs) altitudinal variations of surface air temperatures based on air temperature data of countrywide scattered 22 stations (15 synoptic and 7 climate stations) in Nepal. Several researchers have reported that rate of air temperature rise (long term trend of atmospheric warming) in Nepal is highest in the Himalayan region (~ 3500 m asl or higher) compared to the Hills and Terai regions. Contrary to the results of previous researchers, however this study found that the increment of annual mean temperature is much higher in the Hills (1000 to 2000 m asl) than in the Terai and Mountain Regions. The temperature lapse rate in a wide altitudinal range of Nepal (70 to 5050 m asl) is -5.65 °C km-1. Warming rates in Terai and Trans-Himalayas (Jomsom) are 0.024 and 0.029 °C/year respectively.
Interacting inclined strike-slip faults in a layered medium
Authors: MANNA KRISHANU , SEN SANJAY
Published: December 2021

Two inclined, interacting, strike-slip faults, both buried, situated in a viscoelastic layer, resting on and in welded contact with a viscoelastic half space, representing the lithosphere-asthenosphere system, is considered. Solutions are obtained for the displacements, stresses and strains, using a technique involving the use of Green’s functions and integral transforms, for three possible cases - the case when no fault is slipping, the case when one fault is slipping and the other is locked and the case when both the faults are slipping.
The effect of sudden movement across one fault on the shear stress near the fault itself and near the other faults has been investigated. Some situations are identified where a sudden movement across one fault results in the release of shear stress near the other fault, reducing the possibility of seismic movements across it. Other situations are also identified where a sudden movement across one fault increases the possibility of seismic fault movements. A detail study may lead to an estimation of the time span between two consecutive seismic events near the mid points of the faults. It is expected that such studies may be useful in understanding the mechanism of earthquake processes and may be identified as an earthquake precursor.
Estimation of solar radiation using two step method in West Bengal
Authors: ROY SUKUMAR , PAL SNIGDHA , CHAKRAVARTY NABAJIT
Published: December 2021

Solar radiation is the main source of energy for many physical, chemical and biological process .Estimation of solar radiation from other measured meteorological variables offers an important alternative in the absence of availability of measured solar radiation data. In this paper, we validate and assess five commonly used air temperature based models. The weather data of Dumdum (a station in Gangetic West Bengal) has been taken to observe whether the same works for this region or not. We have also validated and assessed a Local power-2 model (polynomial with degree two) with the same station, i.e.,  Dumdum (22.39° N, 88.27° E) and found it to give a more good result than Local model (linear in nature) so far developed. However the two step method to estimate solar radiation from the commonly measured air temperature in two steps gives more accurate estimation of solar radiation of a place. The model performance is evaluated using different law of error. Results show that the two step method gives good performance and significantly outperforms the temperature based models as claimed by our predecessors. The parameters of S/S0 equation were calculated by multiple regression model and was used `in the two step method for calculating the solar radiation. It is found that the two step method using the parameters determined by the proposed equations gives good performance. Therefore the two step method with the parameters determined by the proposed equations could also be used to estimate solar radiation in West Bengal and also at different places in India having similar topography. It is believed to be useful for the site where no measured solar radiation and sunshine duration data is available, whereas the air temperature are commonly measured.
Osteochondral Fractures After Patellar Dislocation: Current Concepts
Authors: Khan Shehzaad A. , Baghdadi Soroush , Carey James L. , Moores Thomas S. , Sheth Neil P. , Ganley Theodore
Published: December 2021

Osteochondral fractures of the knee occur frequently after acute patellar subluxation or dislocation. They can be challenging to manage because of the difficulty in diagnosing and treating these injuries in a timely fashion, in addition to choosing the optimum fixation method. This review presents the background, considerations for patient evaluation, and the best treatment options available for osteochondral fractures.
Popular Culture and Hegemony in Novel Everything Everything (A Discourse Analysis)
Authors: Handayani Wuriy , Lustyantie Ninuk , Zuriyanti Zuriyanti
Published: December 2021

Budaya adalah cara orang berperilaku, bersosialisasi dengan orang lain dan menggunakan bahasa yang biasa dia gunakan. Budaya dapat berubah dalam banyak hal. Cara orang berbicara, cara orang memakai pakaian, dan cara orang menggunakan teknologi. Budaya pop dapat ditemukan dalam cerita Everything Everything oleh Nicola Yoon. Hal ini tercermin dalam cara karakter berperilaku dan cara karakter memiliki hubungan dengan orang lain. Salah satu faktanya, novel ini memiliki kisah romantis yang disukai oleh orang-orang saat ini. Novel ini juga menunjukkan budaya yang berbeda dari dunia yang berbeda. Selain itu, novel ini menunjukkan bagaimana remaja berperilaku di era mienial. Peneliti dalam novel ini mencoba untuk mengetahui beberapa karakteristik budaya populer dan hegemoni. Novel ini dianalisis menggunakan metode kualitatif. Analisis wacana digunakan untuk menganalisis data dalam novel ini. Bagian analisis wacana yang digunakan adalah analisis semiotika oleh Roland Barthes dan analisis wacana struktur mikro oleh Halliday. Berdasarkan penelitian, penulis menemukan budaya populer berkaitan dengan kehidupan remaja Amerika. Penulis juga menemukan beberapa hygemoni seperti kebebasan, perkawinan, keluarga dan dominasi orang-orang yang bekerja di posisi tinggi.
Peran Guru dalam Membangun Karakter dan Moral Siswa Melalui Pendidikan Kewarganegaraan
Authors: Hakim Aulia Nur , Dewi Dinie Anggraeni , Furnamasari Yayang Furi
Published: December 2021

Lunturnya moral generasi bangsa Indonesia saat ini mengancam hilangnya jati diri bangsa Indonesia yang berpengang teguh pada nilai-nilai Pancasila. Melalui Pendidikan Kewarganegaraan siswa akan dilatih untuk berpikir  kritis, bertanggung jawab, berjiwa nasionalis serta berperilaku demokratis yang dapat membangun karakter serta moral siswa di sekolah. Penelitian ini bertujuan untuk mengkaji bagaimana Pendidikan Kewarganegaraan dapat membentuk karakter dan moral siswa serta bagaimana peran guru dalam membangun karakter dan moral siswa di sekolah. Metode yang digunakan dalam penelitian ini adalah metode deskriptif kualitatif. Yaitu dengan menyajikan data berdasarkan fakta yang ada di lapangan. Hasil dari penelitian yang dilakukan adalah Pendidikan Kewarganegaraan dapat membantu mengembangkan karakter dan moral siswa melalui penanaman nilai-nilai postitif yang didasarkan pada nilai-nilai Pancasila. Guru juga memiliki kewajiban untuk mendidik siswa, melatih diri siswa serta memotivasi anak didiknya agar dapat menjadi manusia yang bermoral dan bermartabat. Dengan begitu, generasi bangsa indonesia yang bermoral dan berkarakter akan tetap melekat pada jiwa bangsa Indonesia.
The importance of dietary balance at COVID-19: the systematic review
Authors: Brugnoli Mairim Ira Silva , Garrett Diogo Augusto de Almeida
Published: December 2021

Introduction: COVID-19 disease has been heralded as a global pandemic by the World Health Organization. Dietary therapy and immunity play a decisive role in SARS-CoV-2 infection. In this sense, the lack of regulation and the excessive immune response to the viral stimulus produces an exacerbated pro-inflammatory cytokines (cytokine storm), reaching the state of hyperinflammation. Objective: To conduct a systematic review of the main considerations in the management of dietary therapy in the control or prophylaxis of COVID-19. Methods: Clinical studies with qualitative and/or quantitative analysis were included, following the rules of the systematic review-PRISMA. Results: A total of 370 articles were found involving dietary therapy, immunity, and COVID-19. A total of 107 articles were evaluated in full, and 28 were included and discussed in this study. Underlying systemic inflammation is believed to exacerbate COVID-19 infection. Studies have shown that there is a high risk of mortality in individuals with pre-existing health problems, such as diabetes, hypertension, cardiovascular disease, and obesity. Nutritional status is known to play a significant role in patient outcomes. It is necessary to follow a diet characterized by anti-inflammatory properties to benefit or prevent COVID-19. Adequate supplies of zinc, selenium, and vitamin D are essential for resistance to other viral infections, immune function, and reduced inflammation. There are nutritional triggers to favor immune-strengthening responses, as well as improving the performance of mitosis, meiosis, and all cellular functioning, all of this functioning is directly integrated with the energy balance and nutritional status of the body. Endogenous metabolites and nutrients in the diet can directly influence epigenetic enzymes. Conclusion: It is necessary to control the activities of inflammatory mediators through modifiable risk factors, such as diet, exercise, and healthy lifestyle choices to control or prevent the harmful effects of COVID-19.
The influence of diet patterns on Alzheimer’s risk: a concise systematic review
Authors: Machado Sayonara Carrijo , Zotarelli Filho Idiberto José
Published: December 2021

Alzheimer's disease (AD) is a progressive neurodegenerative disorder responsible for the main cause of dementia, and the increasing worldwide prevalence of AD is a major public health concern. Studies suggest that diet and nutrition may be important modifiable risk factors for AD. In addition, intestinal microbial metabolites and their effects on host neurochemical changes can increase or decrease the risk of AD. The aim of this literature review article is to discuss the relationship between dietary patterns, foods, gut microbiota, micro and macronutrients, and cognitive disorders, especially Alzheimer's. The results show that the excessive generation and accumulation of reactive pro-oxidant species over time can damage proteins, lipids, carbohydrates, and nucleic acids. Over time, this oxidative stress can contribute to a variety of age-related degenerative diseases. Therefore, antioxidant foods and healthy eating patterns, such as the Mediterranean diet, can contribute to reducing oxidative stress and consequently reducing the risk of Alzheimer's.
Gluten intolerance and hashimoto thyroiditis: an integrated review
Authors: Araújo Etianne Andrade , Kerkhoff Sabrina Portela
Published: December 2021

The advent of agriculture about 10,000 years ago enabled the massive and widespread use of grains containing gluten in food. Thus, it represented an evolutionary challenge that has not yet been overcome and created the conditions for the development of diseases related to exposure to gluten in humans. The so-called hypersensitivity involves any abnormal reaction resulting from eating a particular food. We are now looking at another interesting phenomenon that is causing great confusion among healthcare professionals. The number of individuals embracing a gluten-free diet appears far greater than the predicted number of celiac patients, fueling a global gluten-free product market approaching $2.5 billion (US) in global sales in 2010. This trend is supported by the notion that, along with celiac disease, other conditions related to gluten intake have emerged as health concerns. Hashimoto's Thyroiditis is an autoimmune disease and the most common cause of hypothyroidism in our environment. It occurs with high familial aggregation and there seems to be a clear genetic predisposition, with an apparent autosomal dominant inheritance of autoantibodies in affected individuals. Food intolerance and allergies and intestinal permeability can accompany hypothyroidism. Food (food intolerance and allergies), bacteria, viruses, chemicals, excess bacterial growth in the intestine, intestinal permeability, and contaminants are the main culprits for the autoimmune thyroid disease – Hashimoto's thyroiditis.
Dysbiosis and obesity: implications of the gut microbiota
Authors: Pinto Alexandre Carli , Cavalcante Danilo Everton Cunha , Araújo Etianne Andrade , Cabral Francione Moreira , Santos Jhonatas Mota , Costa Kaline Viana
Published: December 2021

Introduction: Obesity has been considered a public health crisis, contributing as a risk factor for several important chronic diseases and even death. Considering this fact, it is noteworthy that there is a fundamental relationship between the intestine and health, and this organ is considered by modern medicine as our second brain in the concept of intestinal permeability. Within the evaluation of the food process, effective nutritional absorption can be altered due to imbalances, such as malabsorption, drug-nutrient interaction, changes in mucosal permeability, and, consequently, an imbalance in the gut microbiota. Dysbiosis is characterized by these negative changes that occur in the intestine. In this sense, the present systematic review study sought to answer: What influences can the microbiota composition have on the metabolic syndrome and obesity process? Objective: To elucidate the relationship between the presence of intestinal dysbiosis in the pathogenesis of obesity. Methods: This is a bibliographic review work where the MEDLINE, PubMed, and SciELO databases were consulted using the following descriptors: Human gut microbiota, obesity, dysbiosis. Results and Conclusion: Based on the literature that supports this theme, it was possible to observe that in the obese population there is an increase in bacteria of the genus Firmicutes and a decrease in the genus Bacteriodetes, with the blocking of factors and proteins that regulate the homeostasis of the absorption of lipids and fatty acids being observed thus being able to alter the energy metabolism leading to a greater accumulation of adipose tissue.
The relationship between melatonin and sleep quality and its weight loss benefits
Authors: Pinto Alexandre Carli , Cavalcante Danilo Everton Cunha , Araújo Etianne Andrade , Cabral Francione Moreira , Santos Jhonatas Mota , Costa Kaline Viana
Published: December 2021

Melatonin is an endogenous substance easily found in the body. It is conceptualized as a hormone, derived from serotonin, synthesized by the pineal gland during the night period. As a hormone, melatonin has several functions, such as immunomodulation, antioxidant, anti-inflammatory, and antitumor, however its most compliant function is the control of the circadian rhythm, in addition to regularizing seasonality. Sleep is one of the primordial needs of the human being, after a period of physical and mental activities, it has a fundamental role to relax and re-establish the organism for a new cycle of activities. Thus, melatonin acts as a metabolism regulator influencing the quality of life, and its effectiveness in inducing sleep has led pharmaceutical companies to launch its synthetic version, widely sold as a supplement in some countries such as the United States and Europe. To analyze the importance of melatonin in the regulation of sleep, as well as to characterize its functions in the body that contribute to weight control. The work methodology consisted of a literature review, carried out through previously published research studies. Based on the literary subsidies that supported this research, it is concluded that the benefits achieved with the use of melatonin encompass the alignment of the sleep cycle and contribute to weight control, which may influence weight loss, as well as in other areas of the body.
Obesity, bariatric surgery, and weight regain parameters: a concise systematic review
Authors: Grätsch Sibelle
Published: December 2021

Introduction: Obesity, an easily diagnosed disease, is multifactorial, chronic, and difficult to manage. It has increased alarmingly and is now one of the main public health problems. It is associated with several comorbidities and poorer quality of life. Bariatric surgery is currently widely accepted and described in the literature as the most effective method for the treatment of obesity. Even though this is the best method, weight regain (WR) is also checked. In the literature, there are several parameters used to configure WR, and with that, several results are presented. Objective: This paper aims to review the parameters used to assess WR after bariatric surgery. Method: A bibliographic review of the last 5 years was carried out in the PubMed and Scielo virtual databases with the following keywords: bariatric surgery, obesity, and weight regain, in October and November 2019. Result: Lack of unanimity in the definition and parameters for WR is still a reason for further studies. And with that, the results are also presented in a varied way, depending on the parameter used. Conclusion: The subject is relatively new and there is a need for more studies to define and quantify the meaning of WR, to also improve the approach and management of the patient with weight regain. But there seems to be a tendency to adapt itself as a favorable response to surgical success when at least 50% excess weight loss (%EWL) and > 20% total weight loss is achieved, and that any regain should not be used. as a parameter to define it.
Medical nutrition therapeutic approach of non-alcoholic fatty liver: diet, nutraceuticals, phytotherapy and probiotics
Authors: Oprea Cristian , Ribas Filho Durval
Published: December 2021

Although the genetic and pharmacological research of the non-alcoholic fatty liver disease (NAFLD), the commonest liver disease in the world, affecting more than a quarter of the population, shows a promising future, the non-pharmacological therapy continues to be an important approach of this concerning public health issue. The present study focused on the therapeutical potential of the diet and mainly the phytotherapy, nutraceuticals, and probiotics use, employing the literature review methodology by a selection of recent (last 5-10 years) national and international articles from the PubMed and Google Scholar databases. The conclusion was that the non-pharmacological medical nutrition approach could be considered as a first-line therapeutical option for NAFLD due to its low cost, few adverse effects, and a mainly positive impact on an individual's health and life quality.
Kalp Hastalıklarında Cinsiyetin Rolü
Authors: Usalp Songül
Published: December 2021

Amaç: Çalışmamızda, kardiyovasküler hastalıkların kadın ve erkeklerdeki seyrini, sıklığını, bu hastaların takiplerinde kalp fonksiyonlarında değişiklik olup olmadığını araştırmayı hedefledik.Materiyal ve metod: Hastanemiz kardiyoloji polikliniğine çeşitli kalp rahatsızlıkları nedeniyle başvuran hastaların dosyaları geriye dönük tarandı, erkek ve kadın olarak iki gruba ayrılan hastaların koroner an-jiografileri, geçirmiş oldukları kalp ameliyatları, başvuru ve sonrasındaki ekokardiyografik bulguları karşılaştırıldı.Bulgular: Çalışmaya 270 bayan (ortalama yaş 63.8 yıl) ve 271 erkek (ortalama yaş 62.4 yıl) hasta alındı. Koroner arter hastalığı (KAH), kalp yetersizliği, dejeneratif mitral kapak hastalığı (MKH) oranı ve serum kreatinin düzeyleri erkeklerde fazlaydı (p<0.05). Diyabetes mellitus, kronik obstrüktif akciğer hastalığı, diyaliz tedavisi, serebrovasküler hastalıklar, hipertrofik kardiyomiyopati, kalp pili uygulaması açısından her iki grup arasında fark yoktu (p>0.05). Kadınlarda hipertansiyon, Takotusubo kardiyomyopatisi, ro-matizmal MKH erkeklere göre sıktı. Hem kadınların hem erkeklerin takiplerinde sol ventrikül ejeksiyon fraksiyonunda (SVEF) belirgin düşme ve sistolik pulmoner arter basıncında (SPAB) anlamlı artış izlendi (p<0.001). Her iki cinsiyette yaş, önemli bağımsız bir risk faktörü olarak bulundu (p<0.05).Sonuç: Erkeklerde KAH, dejeneratif MKH ve kalp yetersizliği, kadınlarda ise romatizmal MKH ve Ta-kotsubo kardiyomyopatisi daha fazlaydı. SVEF nispeten kadınlarda korunmuştu, fakat, her iki cinsiyette de takipte, hem SVEF’de düşme, hem SPAB da artış olmaktaydı. Yaş her iki cinsiyette KAH için bağımsız prediktif risk faktörü idi.Anahtar kelimeler: Kalp hastalıkları, cinsiyet, ekokardiyografi
Anxiety And Risk Of Cardiovascular Disease
Authors: Rama Agastya Komang , Agung Riatmojo Andi , Abdi Akbar Rauchsan
Published: December 2021

Anxiety is a normal emotion that is owned by every individual. Pathologically increased anxiety can not only give rise to other anxiety disorders but can also lead to other mental illnesses. Anxiety is a type of mental disorder that is quite common in Europe, Switzerland, Iceland, Norway in 2010 it was found that the prevalence for 12 months was 14% and 61.5 million people were affected. According to WHO in the global population with anxiety disorders in 2015 the percentage was 3.6% and it was more common in women with a percentage of 4.6% compared to 2.6% for men. Individuals with symptoms of anxiety are likely to experience the effects of interference that can lead to metabolic syndrome. Metabolic syndrome leads to progressive and clustering of several metabolic risk factors that directly increase the risk of death from cardiovascular disease (CVD, type 2 diabetes mellitus). last year from 10% to 63.2%. Anxiety disorders appear to be caused by the interaction of bio-psychosocial factors. Genetic susceptibility interacts with stressful situations or the presence of trauma to produce a clinically significant syndrome. Treatment measures include pharmacological, psychological, and combination therapies. all are therapeutic measures for all anxiety disorders, selective serotonin is a first line agent for several anxiety disorders, including panic disorder, social anxiety, generalized anxiety disorder.Psychotherapy and pharmacotherapy should be given and both therapies are equally effective. The choice in determining the therapy given must be considered according to the severity of the disorder.
The Effect Of Relaxing A Deep Breath On Anxiety Levels
Authors: Sajidah Holila , Khairunnisa Salwa , Nabila Cahya
Published: December 2021

Emotions and breathing are closely linked in a complex feedback loop. Understanding this interrelationship between breathing and emotions is critical to better understanding how to deal with anxiety, stress, depression, and emotional disturbances. During emotional attacks and anxious states, the autonomic nervous system triggers physiological variables such as heart rate, breathing, blood pressure, hormonal secretions, palpitations, gastrointestinal functions suddenly increase as a result of which the normal social and behavioral functions of the individual are disturbed. It is generally believed that deep breathing, practiced with various techniques, such as qigong and yoga, can promote relaxation. Source searches were carried out on the online portal of journal publications as many as 10 sources from Medscape, Google Scholar, National Center for Biotechnology Information (NCBI) with the keywords anxiety, relaxation, and deep breathing. Deep breathing relaxation has been shown to be effective in reducing the perception and symptoms of anxiety. Deep breathing offers several advantages over conventional therapies currently used to treat anxiety problems. These advantages include a non-pharmacological approach, safety, minimal space requirements, ease of learning, and ease of practice.
Recognizing Sexually Transmitted Infections And Their Treatment
Authors: Septiana Nabilla , Ramdhani Kusuma Dinie , Hapsari Yunita
Published: December 2021

Sexually Transmitted Infections (STIs) are diseases that can be transmitted from one person to another, can be caused by bacteria, viruses, parasites, and fungi. STIs can be transmitted through vaginal, anal, and oral sex. This article aims to identify STIs and their management. The sources used are scientific journals and textbooks. Source searches were conducted on the online portals of journal publications such as the National Center for Biotechnology Information / NCBI (ncbi.nlm.nih.gov) and Google Scholar (scholar.google.com). Transmission of STIs can occur due to interactions between agents (disease-causing factors), hosts (humans as hosts), and the environment (environmental factors). The increase in the incidence of STIs is influenced by several factors, including demographic changes such as very high population growth, increased community movements due to work or tourism, advances in IT-based technology (Technology Information) and socio-economic improvements.
Pediatric Acute Respiratory Distress Syndrome (PARDS) On Pediatric COVID-19 Patients
Authors: Rahmah Siti , Wahyu Alfian Muharzami Lalu , Akhdani Almaesy Lastri , Nurhayati Putri , Sasmitha A Ridha
Published: December 2021

At the end of 2019, there was a pandemic happening in the world, called the novel Coronavirus disease-19 (COVID-19). Various spectrums of disease from COVID-19, one of which is ARDS. The incidence of COVID-19 in children is not as much as in adults. However, in children under one year of age it can get worse. The main characteristic of worsening infection is the occurrence of ARDS.  Objective: To find out the best treatment for PARDS in COVID-19 patients. Method: The writing of this article uses various sources from scientific journals to government guidelines and related institutions. Search articles using the keywords “Acute Respiratory Distress Syndrome”, “ARDS”, “Pediatric Respiratory Distress Syndrome”, “PARDS”, and “PARDS on COVID-19” Result and Discussion: PARDS was defined based on PALICC in 2015. Pathophysiology of PARDS in COVID-19 patients is still unclear. However, there is a theory that explains the way SARS-Cov-2 enters cells, namely through membrane fusion, giving rise to ARDS. The difference in handling PARDS for COVID-19 patients is that the handling technique is more alert to the risk of aerosols. Conclusions: There are differences in the handling of PARDS for COVID-19 patients in the technique by reducing the risk of virus transmission by preventing leakage when using a ventilator and using a bacterial/virus filter, as well as rescuers and staff using complete PPE during the procedure.
Preliminary Study On Latent Membrane Protein-1 (LMP-1) And Bcl-2 Associated X (BAX) In Exosomes Of Patients With Nasopharingeal Cancer In NTB Provincial Hospital
Authors: Angrayany Sapar Puput , Kadriyan Hamsu , Yudhanto Didit
Published: December 2021

Nasopharyngeal cancer is one of the most common types of cancer in Indonesia, especially head and neck cancer. One of the etiology of this cancer is infection with Epstein-Barr virus. Early diagnosis is difficult to establish because the early signs and symptoms of nasopharyngeal carcinoma are not specific. Examination of latent membrane protein-1 (LMP1) oncogene expression and BCL2-associated X (BAX) gene expression proved to be useful in the identification of nasopharyngeal cancer. LMP1 oncogene is an oncogene that functions as a tumor necrosis factor receptor (TNFR), so that apoptosis does not occur and promotes invasion and metastasis. The BAX gene is a pro-apoptotic gene that inhibits cancer development, but its regulation will be downregulated by LMP1 because LMP can protect B-cells from apoptosis.
Improving the Quality of Public Policy by Involving Stakeholders and the Community
Authors: Muhafidin Didin
Published: December 2021

This article is attempting to investigate cooperation, one of the vital Great Administration components, as one concept which is expounded not as it were as only partaking, but too contains an exertion to control awareness to inundate within the entire political handle really. There ought to be a genuine ruddy line between going to per se and partaking with information. Fair interest may be a frame of pseudo support, which is built up based on mobilization. Cooperation with mindfulness, on the other hand, is more contributing to making essential changes within the political handle. Within the setting of support, this sort of understanding is vital. Other than, this article is considered any frame of open interest in defining arrangements to oversee Indonesia, mainly the local people. They got to be relatively acknowledged, especially after the application of neighborhood independence, whether or not they specifically relate with broader open interface. This moreover plays a feedback of fair interest in Indonesia, which has caused Indonesia to be cleared out behind by created nations due to the latter's mind blowing political mindfulness. Advancement may be well running by depending on the government quality, but the comes about will be much way better when the occasion completely get open bolster and cooperation.
Effects of Leadership, Organizational Culture & Competence on Procurement of Government Goods and Services at the Directorate of Prevention and Control of Direct Communicable Diseases of the Indonesian Republic Ministry of Health
Authors: Pujoyono Surya , Akbar Bahrullah , Djaenuri Aries , Ilham Muh.
Published: December 2021

The research objective is to determine the effect of leadership on government procurement of goods and services, organizational culture of government procurement of goods and services, competence on government procurement of goods and services, leadership influence through organizational culture on government procurement of goods and services, leadership influence through competence on procurement of goods and government services, and formulate new concepts from the results of the discussion of the effects of leadership, organizational culture, and competence on the procurement of government goods and services. The research sample of 104 respondents was taken fully / fully. Data collection in this research uses a literature study, a research questionnaire, and observation. Data analysis using SEM Analysis. The results found that leadership influences Organizational Culture, Leadership influences Competence, Organizational Culture influences Government Procurement of Goods and Services, Competence influences Government Procurement of Goods and Services, and Leadership influences Government Procurement of Goods and Services.
Analysis of Maritime Welding Policy in the Development of Global Hub Bandar Kayangan in North Lombok, Indonesia
Authors: Raharjo Joko Susilo , Suradinata Ermaya , Lukman Sampara , Wildan Lalu
Published: December 2021

This study aims to find the development of new models, using qualitative research designs with descriptive research types. The research informants were carried out by means of interviews, observations and literature studies as the techniques used in collecting data. While data reduction, data retrieval and conclusion drawing became the technical analysis of qualitative data used in this study. The analysis used in this study is an analysis of the implementation of the public policy model of Grindle (1980) and continued with analysis of ASOCA strategies. The results of this study are 1) Implementation of the global development policy Bandar Kayangan Hub can not be implemented optimally 2) Required strategies for problem solving in decision making. From the results of the analysis of the implementation of public policy based on Empirical Findings of ASOCA strategy analysis, a new concept of implementation strategy model 7 P JSRW was obtained, namely: 1) Government role (delegation process), 2) Zoning regulations, 3) Media role in making public opinion 4) The use of local labor, 5) The role of universities in printing experts, 6) Business actors (attracting investors) 7) Fair legal enforcement.
The Importance of Location, Promotion, and Merchandising in Affecting the Consumer Purchasing Decision: A Case Study in PT Wijaya Motor Bandung, Indonesia
Authors: Suhairi Dadang
Published: December 2021

The purpose of this study was to determine the effect of location, promotion and merchandising on consumer purchasing decisions at PT Wijaya Motor Bandung, Indonesia. This research method uses a quantitative approach. The data collected in this study used the distribution of questionnaires to 118 consumers at PT Wijaya Motor Bandung using a simple random sampling technique. The results of this study indicate that there is a positive and significant effect both partially and simultaneously between location, promotion and merchandising on consumer purchasing decisions at PT Wijaya Motor Bandung, Indonesia.