bluuebunny/crossref_metadata_2025 huggingface dataset:
The Impact of Uncertainty on State-Level Housing Markets of the United States: The Role of Social Cohesion
Authors: Dai Linyan , Sheng Xin
Published: March 2021

While considering the role of social cohesion, we analyse the impact of uncertainty on housing markets across the 50 states of the United States, plus the District of Columbia, using the local projection method for panel data. We find that both short-term and long-term measurements of macroeconomic and financial uncertainties reduce real housing returns, with the strongest effect originated from the macro-economic uncertainty over the long term. Moreover, the degree of social cohesion does not change the nature of the impact of uncertainty on real housing returns dramatically, but the size of the negative effects is relatively large for states with low social cohesion.
Field Monitoring of Aflatoxins in Feed and Milk of High-Yielding Dairy Cows under Two Feeding Systems
Authors: Bervis Noemi , Lorán Susana , Juan Teresa , Carramiñana Juan José , Herrera Antonio , Ariño Agustín , Herrera Marta
Published: March 2021

Aflatoxin M1 (AFM1) is a hydroxylated metabolite of aflatoxin B1 (AFB1) that can be excreted in milk of cows after consuming contaminated feed. The aim of this study consisted of a field monitoring to assess the contamination levels of AFB1 in 60 feed samples from two feeding systems for high-yielding dairy cows and of AFM1 in the corresponding raw milk samples. The aflatoxins were analyzed by in-house validated methods based on high-performance liquid chromatography (HPLC) with fluorescence detection. AFB1 was detected in 55% of feed samples (mean 0.61 μg/kg, with 2 samples exceeding the European Union (EU) maximum level set at 5 μg/kg), with greater incidence and concentration in compound feed than in unifeed rations (p < 0.05). AFM1 was detected in 38.3% milk samples (mean 12.6 ng/kg, with 5 samples exceeding the EU maximum level set at 50 ng/kg), with a higher occurrence in milk of cows fed compound feed, as well as in spring milk compared to that produced in winter. The overall transfer ratio of aflatoxins from feed to milk was 3.22%, being higher in cows fed with compound feed and in spring milkings. In a selection of positive matched samples (n = 22), the ratio AFM1/AFB1 exceeded the European Food Safety Authority (EFSA) estimated 6% threshold for high-yielding dairy cows.
Multi-Mycotoxin Contamination of Maize Silages in Flanders, Belgium: Monitoring Mycotoxin Levels from Seed to Feed
Authors: Vandicke Jonas , De Visschere Katrien , Ameye Maarten , Croubels Siska , De Saeger Sarah , Audenaert Kris , Haesaert Geert
Published: March 2021

Maize silage, which in Europe is the main feed for dairy cattle in winter, can be contaminated by mycotoxins. Mycotoxigenic Fusarium spp. originating from field infections may survive in badly sealed silages or re-infect at the cutting edge during feed-out. In this way, mycotoxins produced in the field may persist during the silage process. In addition, typical silage fungi such as Penicillium spp. and Aspergillus spp. survive in silage conditions and produce mycotoxins. In this research, 56 maize silages in Flanders were sampled over the course of three years (2016–2018). The concentration of 22 different mycotoxins was investigated using a multi-mycotoxin liquid chromatography-tandem mass spectrometry (LC-MS/MS) method, and the presence of DNA of three Fusarium spp. (F. graminearum, F. culmorum and F. verticillioides) was analyzed in a selection of these samples using quantitative polymerase chain reaction (qPCR). Every maize silage contained at least two different mycotoxins. Nivalenol (NIV) and deoxynivalenol (DON) were the most prevalent (both in 97.7% of maize silages), followed by ENN B (88.7%). Concentrations often exceeded the EU recommendations for DON and zearalenone (ZEN), especially in 2017 (21.3% and 27.7% of the maize silages, respectively). No correlations were found between fungal DNA and mycotoxin concentrations. Furthermore, by ensiling maize with a known mycotoxin load in a net bag, the mycotoxin contamination could be monitored from seed to feed. Analysis of these net bag samples revealed that the average concentration of all detected mycotoxins decreased after fermentation. We hypothesize that mycotoxins are eluted, degraded, or adsorbed during fermentation, but certain badly preserved silages are prone to additional mycotoxin production during the stable phase due to oxygen ingression, leading to extremely high toxin levels.
Ion-Acoustic Rogue Waves in Double Pair Plasma Having Non-Extensive Particles
Authors: Jahan Sharmin , Haque Mohammad Nurul , Chowdhury Nure Alam , Mannan Abdul , Mamun Abdullah Al
Published: March 2021

The modulational instability (MI) of ion-acoustic (IA) waves (IAWs) and associated IA rogue waves (IARWs) are studied in double-pair plasma containing inertial positive and negative ions, inertialess non-extensive electrons and iso-thermal positrons. A standard nonlinear Schrödinger equation (NLSE) is derived by employing reductive perturbation method. It can be seen from the numerical analysis that the plasma system supports both modulationally stable (unstable) parametric regime in which the dispersive and nonlinear coefficients of the NLSE have opposite (same) sign. It is also found that the basic features of IAWs (viz., MI criteria of IAWs, amplitude, and width of the IARWs, etc.) are rigorously changed by the plasma parameters such as mass, charge state, and number density of the plasma species. The outcomes of our present investigation should be useful in understanding the propagation of nonlinear electrostatic IAWs and associated IARWs in astrophysical and laboratory plasmas.
Hydrogeochemical and Hydrodynamic Assessment of Tirnavos Basin, Central Greece
Authors: Vrouhakis Ioannis , Tziritis Evangelos , Panagopoulos Andreas , Stamatis Georgios
Published: March 2021

A combined hydrogeochemical and hydrodynamic characterization for the assessment of key aspects related to groundwater resources management was performed in a highly productive agricultural basin of the Thessaly region in central Greece. A complementary suite of tools and methods—including graphical processing, hydrogeochemical modeling, multivariate statistics and environmental isotopes—have been applied to a comprehensive dataset of physicochemical analyses and water level measurements. Results revealed that the initial hydrogeochemistry of groundwater was progressively impacted by secondary phenomena (e.g., ion exchange and redox reactions) which were clearly delineated into distinct zones according to data processing. The progressive evolution of groundwater was further verified by the variation of the saturation indices of critical minerals. In addition, the combined use of water level measurements delineated the major pathways of groundwater flow. Interestingly, the additional joint assessment of environmental isotopes revealed a new pathway from E–NE (which had never before been validated), thus highlighting the importance of the joint tools/methods application in complex scientific tasks. The application of multivariate statistics identified the dominant processes that control hydrogeochemistry and fit well with identified hydrodynamic mechanisms. These included (as dominant factor) the salinization impact due to the combined use of irrigation water return and evaporitic mineral leaching, as well as the impact of the geogenic calcareous substrate (mainly karstic calcareous formations and dolostones). Secondary factors, acting as processes (e.g., redox and ion exchange), were identified and found to be in line with initial assessment, thus validating the overall characterization. Finally, the outcomes may prove to be valuable in the progression toward sustainable groundwater resources management. The results have provided spatial and temporal information for significant parameters, sources, and processes—which, as a methodological approach, could be adopted in similar cases of other catchments.
Le château de Saint-Brisson-sur-Loire, fleuron du renouveau de l’architecture castrale à la fin du xiie siècle
Authors: Hayot Denis
Published: March 2021

Little known until now, the Château of Saint-Brisson-sur-Loire is an exceptional edifice in more ways than one in the history of castle architecture. In spite of modern transformations, it has preserved vestiges of an extremely massive exterior fortification with walls 20 meters high and 4.5 meters thick, as well as traces of a large residential program, which includes open-work windows giving onto the Loire. The original building was the result of a unified construction attributed to Etienne Ier de Sancerre or his brother Guillaume aux Blanches Mains, in the years 1180-1200. With its compact enclosure in the form of an almost triangular hexagone and regularly flanked
Le théâtre d’eau de Tommaso Francini en son jardin de Grandmaisons
Authors: Rostaing Aurélia
Published: March 2021

The waterworks created by Tommaso Francini in his seigniorial gardens at Grandmaions (Villepreux, Yvelines) are one of the lesser known pieces among his works and in the history of French gardens in the first half of the 17th century. An unpublished description and ground-plan show that the fountain-engineer, who became director of French water-ways and fountains, conceived for his own use hydraulic installations with a strong scenography that orchestrates his fidelity to Maria de Medici. This garden is also characterized by the most up-to-date forms of the years 1620-1650 (a great circular waterworks, a great square waterworks, small waterways), but also by certain traits that would become characteristic of the French garden in the second half of the 17th century (alignment of the main parts of the garden according to an overall plan and the fixing of a viewpoint that could apprehend the ensemble at a glance).
Abordagens e temas da Geografia Física
Authors: Sabóia de Aquino Cláudia Maria , Tavares da Silva Francisco Jonh Lennon
Published: March 2021

A geodiversidade e a educação em solo, bem como pesquisas e desafios contemporâneos relacionados às bacias hidrográficas, compõem o cerne desta obra, que traz de volta ao protagonismo as discussões teóricas em Geografia Física, que parecem ser deixadas de lado nos últimos anos. A grandeza da contribuição recai, ainda, na opção pelo objeto de estudo, que nos remete aportar no espaço de vivência dos autores, no caso o estado do Piauí. Este se torna o baluarte do olhar cobiçado dos pesquisadores, tomando-o como projeção das análises, sempre amparados com o rigor científico, em seus alicerces teóricos e metodológicos.
FATORES QUE INFLUENCIAM A NÃO ADESÃO DA MULHER AO EXAME PAPANICOLAU: REVISÃO DE LITERATURA
Authors: Mendes e Silva Valdízia , Pereira Vasconcelos Karla , Dayse de Souza Diniz Danyelle , Marinho de Farias Gizele , Emília Araújo de Oliveira Ana
Published: March 2021

OBJETIVO: descrever os fatores que determinam a não adesão das mulheres ao papanicolau. MÉTODO: trata-se de uma revisão de literatura realizada nas bases LILACS, MEDLINE e SCIELO. Foram incluídos na amostra artigos publicados entre os anos de 2010 e 2020 que estavam disponíveis na íntegra. Foram examinados 37 estudos. Após a análise do resumo, a amostra final foi composta por 12 artigos. RESULTADOS: os resultados obtidos foram dispostos e agrupados em quatro categorias pré-estabelecidas: aspectos sociodemográficos das mulheres; sentimentos negativos gerados pela realização do exame; aspectos ginecológicos relacionados a não adesão ao papanicolau; relação da não adesão com o serviço de saúde. Destacaram-se como causa da não adesão: baixa escolaridade, classe social baixa, menores faixas etárias, tabagismo, baixo peso ou obesidade, desconforto, nervosismo, ansiedade, receio, vergonha, constrangimento, medo, tabus e timidez, bem como ideias preconcebidas a respeito do exame e a falta de atitude. Também foram apontados o não uso de métodos contraceptivos, ter 4 ou mais filhos, ausência de sintomas ginecológicos, não possuir relação conjugal, falta de recursos, materiais, espaço e sobrecarga de trabalho, dificuldade de acesso e insuficiência de vagas, longas filas e marcação aprazada para datas distantes associados às atividades laborais da mulher, falta de oferta profissional, falta de aconselhamento e orientação à paciente, presença do profissional masculino. CONCLUSÃO: observou-se que há diversos fatores que determinam a não adesão das mulheres ao Papanicolau. É de fundamental importância a efetivação de programas que visem a equidade do atendimento, diminuição das iniquidades sociais e oportunização do oferecimento do exame.

Palavras chave: Adesão. Teste de Papanicolau. Saúde da Mulher.
UTILIZAÇÃO DE PLANTAS MEDICINAIS NA GRAVIDEZ E AMAMENTAÇÃO: REVISÃO INTEGRATIVA
Authors: Lima Arruda Rejanne , Olívia de Sousa Garcia Nathália , Lima Arruda Evilanna , Cardoso da Conceição Edemilson
Published: March 2021

OBJETIVO: Identificar estudos que relatem sobre o uso de plantas medicinais por mulheres gestantes ou lactantes. MÉTODOS: Foi realizada uma revisão integrativa (RI) da literatura nacional com abordagem retrospectiva, no período de 2010 a 2020, disponíveis nas bases de dados SciELO, PubMed e Google Acadêmico, utilizando palavras chave: plantas medicinais na gravidez, fitoterápicos na gestação, fitoterapia materna, gestação e amamentação e uso de plantas medicinais. RESULTADOS: Foram selecionados seis estudos, que atenderam aos critérios de inclusão/exclusão, cinco são artigos publicados em periódicos e uma dissertação. Observa-se com os resultados que todas as gestantes analisadas fizeram uso de algum chá de espécie vegetal e que a maior parte não sabiam dos riscos que esse consumo inadequado poderia trazer para o feto. CONCLUSÃO: O uso de plantas medicinais é uma prática comum entre as gestantes e lactantes e devido a capacidade abortiva de algumas espécies deve-se ter conhecimento dos riscos e das quantidades/concentrações seguras antes da utilização.

Palavras chave: Medicina alternativa; produtos naturais, lactantes, gravidez.
HUMANIZAÇÃO DA ASSISTÊNCIA DE ENFERMAGEM FRENTE AO PACIENTE ONCOLÓGICO PEDIÁTRICO
Authors: Pereira Soares Jozilane , Pereira Soares Alves Jéssica , Salvador da Silva Edilson , de Negreiros Moreira Silva Raquel
Published: March 2021

OBJETIVO: Identificar os benefícios da assistência humanizada na oncologia pediátrica descritas na literatura científica. METODOLOGIA: Trata-se de uma revisão integrativa da literatura, realizada nas bases de dados: LILACS e SciELO, a busca foi realizada no idioma português, considerando artigos publicados entre o período de 2011 a 2019, para tanto foram utilizados os descritores: humanização, assistência de enfermagem e oncologia pediátrica. Foram encontrados 82 artigos no LILACS e 34 no SCIELO, foi realizada a exclusão dos repetidos, o que resultou em nove artigos. RESULTADOS: Entre os estudos selecionados, observou-se que os fatores mais prevalentes relacionados aos benefícios da assistência humanizada na oncologia pediátrica foram: i) valorização do vínculo de confiança; ii) comunicação; iii) ter empatia, escuta atenta e respeito a individualidade. CONSIDERAÇÕES FINAIS: A humanização da assistência de enfermagem prestada à criança oncológica representa uma ferramenta vital para a recuperação do paciente, minimizando os traumas e os impactos negativos resultantes da doença.

Palavras chave: Enfermagem Oncológica. Humanização da assistência. Pediatria.
IMPLANTAÇÃO DO PROTOCOLO PREVENTIVO DE BRONCOASPIRAÇÃO EM UM HOSPITAL PÚBLICO DO ESTADO DO PIAUÍ DE ALTA COMPLEXIDADE: RELATO DE EXPERIÊNCIA
Authors: Moura de Souza Félix Manuela , Cerqueira Lemos Viana Wladilleny
Published: March 2021

RESUMO: Objetivo: Descrever o processo de implantação do Protocolo Preventivo de Broncoaspiração Multiprofissional em um Hospital Público do Estado do Piauí de Alta complexidade. Método: Este estudo constitui um relato de experiência, de caráter retrospectivo e descritivo, da implantação do Protocolo Preventivo de Broncoaspiração com ações multiprofissionais, pelo Serviço de Fonoaudiologia do hospital. Os dados referentes à sinalização do risco de Broncoaspiração e atendimento dos pacientes foram coletados através das avaliações fonoaudiológicas realizadas na Unidade de Terapia Intensiva geral do referido hospital. Resultados: Sinalizaram-se 134 pacientes com a placa “nada por via oral”, nas UTIs, no ano de 2020, consistindo em uma das medidas preventivas essenciais que inibe a oferta por via oral de alimentos, água e medicamentos a pacientes com risco de broncoaspiração. Além disso, iniciou-se o acompanhamento e reabilitação dos pacientes. É oportuno ressaltar que, apesar das dificuldades com a pandemia, obteve-se êxito com uma aplicação adaptada e parcial do protocolo, com medidas simples de segurança tanto para profissionais quanto para os pacientes. Conclusão: A experiência relatada aponta que um trabalho preventivo realizado por uma equipe multiprofissional capacitada e engajada impacta diretamente na qualidade da assistência prestada à população, com boas práticas de cuidado e melhor manejo das alterações da deglutição, proporcionando qualidade de vida aos pacientes, redução do tempo de internação e diminuição dos custos hospitalares, mesmo diante de dificuldades no processo de implantação e gerenciamento do Protocolo Preventivo de Broncoaspiração, gerados principalmente pela pandemia da Covid-19.

Palavras chave: Transtornos de Deglutição. Fonoaudiologia. Equipe de Assistência ao Paciente. Protocolos. Segurança.
Peter Ehlen’s Christian Reading of Frank’s Russian Religious Philosophy
Authors: Nazarova Oksana
Published: March 2021

This paper analyzes the problem of Western perceptions of one of the most original branches of the Russian Philosophical Renaissance that occurred at the beginning of the 20th century: namely, the so called Russian Religious Philosophy. This problem still possesses contemporary relevance, owing to the fact that Russian philosophy continues to be engaged in a search for self-identification in respect of Western philosophical contexts. The paper shows that “Russian Religious Philosophy” is perceived by Western thinkers not only as “an exotic cultural phenomenon,” but also as an equal partner in a dialogue: it is considered a significant philosophical achievement, meeting all generally accepted criteria of philosophical creativity. The German Catholic philosopher Peter Ehlen’s monograph on the subject of the religious philosophy of Semyon Lyudvigovich Frank will furnish us, here, with an example of just such an approach. The author of the monograph approaches his subject as something which he himself stands in an essential connection to—something which he, as a researcher, is in a peculiar spiritual communion with. A common spiritual experience of the religious perception of reality determines both Ehlen’s interest in Frank and the specific character of the research undertaken by him. The position of researcher, expected to maintain a certain distance from his or her subject matter, is replaced by that of a co-thinker, engaged in co-experiencing and understanding in depth the ideas of the particular philosopher under examination. The result of this approach is a new synthesis created by Ehlen on the basis of Frank’s philosophy.
Nonetheism: A Non-atheistic Account of a Non-existent God
Authors: Kabay Paul
Published: March 2021

I briefly defend a view I call nonetheism: the claim that God is a non- existent item. I develop a defense that might be acceptable to a theist, but I also note that arguments for atheism would also support this claim. As such, nonetheism is a form of theism that is actually supported by the case for atheism. I begin by showing that it is possible for there to be a non-existent object—that such an idea is coherent. I then argue that a non-existent item is actual and follow this with a defense of the coherency of claiming that God is a non-existent object. The paper concludes by demonstrating that the doctrine of creatio ex nihilo entails the non-existence of God and so any evidence in support of creation from nothing is evidence in support of nonetheism.
Jason Stanley: Know How
Authors: Lechniak Marek , Czarnecki Bolesław
Published: March 2021

The article reviews the book of Jason Stanley, Know How. Oxford: Oxford University Press, 2011.
PENERAPAN AUDIO MUROTTAL AL-QUR’AN DALAM PEMBELAJARAN UNTUK MENINGKATKAN KOMUNIKASI VERBAL PADA ANAK USIA 3-5 TAHUN DI TAUD SAHABAT QURANI
Authors: Prasetya Ayu , Isriani Najamuddin Nur
Published: March 2021

Background : Speech disorders are one of the problems that are often found in children. According to the National Center for Health Statistics (NCHS), based on parents' reports (outside of hearing loss and cleft palate), the incidence of disorders is 0.9% in children under the age of 5 years, and 1.94% at the age of 5- For 14 years, the need for managing disorders of children's verbal communication can be done with a variety of therapies, one of which is Murottal Al-Qur'an therapy. Murottal Al-Qur’an provides sound effect received by the ear and system and then transmitted to all organs of the body. Sound affects the cells of the body that have their own vibrations and cause the cells of the body to rearrange the articles in it. Where the role here is the vagus nerve which helps regulate heart rate, respiration, speech, brings motor sensory impulses to larynx of the heart and diaphragm so that the sound effects on autistic children can improve children’s communication skills. The method used in this research is Experimental Quasy with pre and post without control research design. Sampling using purposive sampling technique, in getting 10 respondents in accordance with inclusion criteria, data collection was done by using questionnaires and observation sheets, namely by using the DDST sheet (Denver Development Screening Test). Observations were made before and after Murottal Al-Qur'an therapy. The collected data is then processed using the Marginal Homogenity Test P value is obtained on the DDST (Denver Development Screening Test) sheet after the Murottal Al-Qur'an therapy is 0.001. The conclusion in this study is that Murottal Al-Qur'an therapy has an effect on verbal communication of children aged 3-5 years in the SaQu (Sahabat Qur'ani) TAUD of Polewali Mandar Regency.
Business Law Service in the Workplace as a Career Trend or To Wage Erosion - Minimum Wage
Authors: Naumovski Ljupcho
Published: March 2021

The author, motivated and motivated by the importance of the minimum wage, tried to make the relevance of this paper based on inconsistencies in the equality of legal regulation of the minimum wage; the theoretical objectivity of the legal regulation of the minimum wage; controversial definition and meaning of minimum wage. Theme. Institution minimum wage in Central and Eastern Europe (CEE). Objectives. Theoretical and legal aspects of the minimum wage in CEE. The purpose of the research - Overview of CEEC in the economic field/relations regarding the current demand for the minimum wage to the workplace. Methodology. The dialectical method with the methods of formal-logical, system-structural, comparative legal and statistical analysis through the study of monographs, scientific literature, analysis of existing laws and regulations, data synthesis. The methodological basis of this work is the study of professional literary sources on this topic, their analysis and generalization so that this work will use excerpts from the above sources. Theoretical basis. The scientific basis of the research is the study of monographs, scientific articles of general theoretical and sectoral nature of scientists in the world. The empirical basis is from international legal acts, laws and other regulatory legal acts. In this situation, we mean the importance of the level of payment, but not the inadmissibility of determining a payment less than the minimum wage. However, for the minimum wage to fulfil its economic, social and legal function today, it must be set at a sufficiently appropriate level.
STUDY ON EFFICACY AND SAFETY OF RIPASUDIL HYDROCHLORIDE IN
TREATMENT OF NEWLY DIAGNOSED PRIMARY OPEN ANGLE GLAUCOMA
Authors: Ghanta Debalina , Roy Sudeshna , Samanta Taneema
Published: March 2021

Aim: The study aims at evaluating the lowering effect of Intraocular pressure (IOP) and tolerability of Ripasudil(0.4%) ophthalmic solution, a
selective rho kinase1 inhibitor, as monotherapy in newly diagnosed primary open angle glaucoma patients. Background: Glaucoma is a chronic
progressive optic neuropathy causing irreversible blindness around the world. Current treatment strategy stems from concept of lowering IOP,
which is a key modiable risk factor. Ripasudil also known as K 115,is the world's rst Rho-associated coiled-coil-containing protein Kinase
1(ROCK1) inhibitor that lowers IOP by directly acting on trabecular meshwork,increasing conventional outow. Methods: This prospective,
interventional study included 53 patients of newly diagnosed primary open angle glaucoma.0.4% Ripasudil ophthalmic solution was instilled
twice a day as the primary treatment. The primary endpoint was the degree of IOPreduction after 6 months of treatment, whereas the secondary end
points were percentage of patients reaching the predened target IOP and incidence of adverse effects. Results: We examined 53 eyes of 53
primary open angle glaucoma patients. The IOP reduction (relative percentage IOP reduction)from baseline was -2.3 mm Hg(-1.7 to -2.9 mm
Hg,95%condence interval ,P<0.001).The predetermined target IOPwas achieved by 54.7% population(29 among 53 patients).The most common
adverse effects noted were conjunctival hyperaemia (54.7% of patients),allergic conjunctivitis(35.8% of patients) punctate keratitis(11.32% of
patients), blepharitis(15.09% of patients), headache(24.5% of patients), bradycardia(9.43% of patients). Conclusion: Administration of 0.4%
Ripasudil ophthalmic solution monotherapy revealed IOPlowering effect and acceptable safety prole in POAG patients. As ROCK inhibitors are
novel anti-glaucoma drug, more data and studies are needed to establish best practices for the treatment of the patients.
AESTHETIC AMELIORATION OF GINGIVAL RECESSION BY MODIFIED
CORONALLY ADVANCED FLAP PROCEDURE: A 6 MONTHS FOLLOW-UP
INTERVENTIONAL STUDY
Authors: Rajesh Namburi , Poornima Rajendran
Published: March 2021

Background:In recent times, aesthetics has become a major reason for the patients to seek the dentist. Gingival recession of the anterior teeth leads
to long tooth appearance thereby hampering the aesthetics. The aim of the present study is to assess the efciency of modied coronally advanced
ap (MCAF) technique in combination with platelet-rich brin (PRF) for recession coverage of Miller's class I and II cases. Materials and
method: 10 patients with Miller's class I or class II gingiva were treated by modied coronally advanced ap (MCAF) technique in combination
with platelet-rich brin (PRF). The clinical parameters such as gingival index (GI), bleeding on probing (BOP), probing pocket depth (PPD),
clinical attachment level (CAL), width of attached gingiva (WAG), thickness of attached gingiva (TAG) and the height of gingival recession
(HGR) were recorded at baseline, 3 months and 6 months follow-up visits. Results: All the clinical parameters showed signicant improvement at
3 months and 6 months post-operatively when compared with the baseline values. The results obtained during the initial follow-up visit remained
stable over a period of 6 months. Conclusion: MCAF is a foreseeable technique to achieve gingival recession coverage. Additionally, the use of
PRF enables in improved WAG and TAG due to the release of growth factors.
Acute Ischemic Colitis in a Covid-19 Patient
Authors: L Urciuoli , E Guerriero
Published: March 2021

Coronavirus disease 2019 (COVID-19) is caused by a novel strain of coronavirus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which was first discovered in Wuhan, China, in December 2019. The virus has quickly spread around the globe and has been declared a global pandemic by the World Health Organization.

Although in COVID-19 respiratory symptoms predominate, there is a relevant body of evidence that initial symptoms and complications of COVID-19 are not limited to the pulmonary system, but can involve also the gastrointestinal tract.

We report a case that presented with ischemic colitis in the setting of PCR-confirmed SARS-CoV-2 infection.
Analyzing and comparing the impacts and outcomes of two different types of surgeries - Minimally Invasive Surgeries (MIS) and Conventional Surgeries (CVS) on patients suffering from Degenerative Mitral Valve Diseases
Authors: M Halim , M AlSayegh , CA Umenne , P Vadithya , SV Panicker , KA Israel , A Halim
Published: March 2021

Background: Degenerative Mitral Valve Disease (DMVD) is the most common cause of Mitral Regurgitation (MR) and the main reason for surgical intervention in patients with heart diseases. Traditionally, open-heart surgery or else sternotomy was the main surgical approach used until a few decades ago when Minimally Invasive Surgical (MIS) approaches came into existence. MIS approach is thought to have superior clinical outcomes while minimizing hospital and ICU stay; blood loss translating to fewer blood transfusions, and lower incidence of complications. Despite many promising institutional and regional results of benefits of MIS over the conventional surgery, the adoption of MIS worldwide in Mitral Valve Repair (MVR) has been so poor. There are still arguments on the surgical and clinical benefits of MIS and more importantly the cost and the expertise involved in conducting MIS. Objective: This study aimed at comparing the costs, clinical and surgical outcomes of MIS with conventional sternotomy MVR surgeries in patients with DMVD. Methods: Electronic databases such as MEDLINE, PubMed, Science Direct, and Google Scholar were searched for relevant peer-reviewed articles comparing costs and clinical outcomes of MIS with the conventional surgery/sternotomy in DMVD from January 2013 to November 2020. A total of 7 articles were identified as most relevant and therefore included in the meta-analysis. Results: Findings from the meta-analysis pointed out that repair of the mitral valve using MIS patients with DMVD has benefits such as short ICU, intubation and hospital duration; less loss of blood and therefore less need of blood transfusion; low postoperative infection rates; smaller incisions; early ambulation and return to activities of daily living over conventional surgery while maintaining similar costs of care and clinical outcomes as a sternotomy. Conclusions: Given the added advantages of MIS in mitral valve surgeries, cardiac surgeons should consider it over the conventional open surgeries in patients with DMVD. In this regard, more surgeons and nurses need to gain competency in conducting MIS through training and fellowships; hospitals need to acquire the needed infrastructure to enable the adoption of MIS.
DEVELOPMENT OF A DIESEL GENERATOR SET DIAGNOSTIC SYSTEM
Authors: Абидова Е.А. , Дембицкий А.Е. , Чернов А.В.
Published: March 2021

Рассмотрены проблемы разработки системы диагностики дизельного двигателя. Разработана модель на основе эмпирических данных о проявлениях дефектов в диагностических сигналах. Предложено на этапе проектирования проверять с использованием модели соответствие системы критериям качества.

The problems of developing a diesel engine diagnostic system are considered. A model is developed based on empirical data on the signs of defects in diagnostic signals. It is proposed to check the compliance of the system with the quality criteria using the model at the design stage. The comparison of different variants of systems in terms of compliance with the desired quality indicators is given.
DEVELOPMENT OF AN AUTOMATED ENVIRONMENTAL MANAGEMENT SYSTEM FOR AN INDUSTRIAL ENTERPRISE
Authors: Киселева Т.В. , Михайлов В.Г. , Ивушкин А.А. , Михайлова Я.С.
Published: March 2021

В статье описана предложенная автоматизированная система управления природоохранной деятельностью промышленного предприятия, включающая основные эколого-экономические инструменты.

The proposed automated environmental management of an industrial enterprise is described in the article, including the main environmental and economic tools.
EVOLUTIONARY METHODS AND GENETIC ALGORITHMS FOR NUMERICAL CALCULATION OF THE OPTIMAL DESIGN OF NON-RIGID ROAD SURFACES
Authors: Тайлакова А.А. , Пимонов А.Г.
Published: March 2021

В статье представлена оптимизационная модель для расчета конструкций нежестких дорожных одежд, обосновано применение эволюционных алгоритмов в сочетании с полным перебором и параллельными вычислениями и описан разработанный гибридный генетический алгоритм

The article presents an optimization model for calculating structures of non-rigid road surfaces, justifies the use of evolutionary algorithms in combination with full search and parallel calculations, and describes the developed hybrid genetic algorithm for optimizing the design of non-rigid road surfaces at the cost of materials of structural layers.
ARCHITECTURE OF THE REPAIR AND MAINTENANCE MANAGEMENT SOFTWARE FOR A SERVICE ENTERPRISE
Authors: Титарёв Д.В. , Кривцанов С.О.
Published: March 2021

В работе изложен обзор архитектур для программного комплекса управления ремонтами и техническим обслуживанием для сервисных компаний. В рамках проведенной работы были изучены методологии EAM и ITSM, рассмотрены три различные архитектуры, приведены их описания, достоинства и недостатки.

The paper provides an overview of the architectures for the repair and maintenance management software package for service companies. As part of the research work, the EAM and ITSM methodologies were studied, three different architectures were considered, their descriptions, advantages and disadvantages were given.
SIX LEVIERS POUR REVALORISER L’IMAGE DE LA LOGISTIQUE
Authors: Paché Gilles , LARGE RUDOLF O.
Published: March 2021

Essentielle au fonctionnement des échanges, et largement mise en lumière pendant la crise sanitaire de la Covid-19, la logistique est loin d’être reconnue à sa réelle valeur. Son image est certainement à améliorer, notamment aux yeux des étudiantes et étudiantes en sciences de gestion et du management, en jouant sur plusieurs leviers d’action. L’article suggère la mise en œuvre, a priori aisée, de six leviers pour revaloriser l’image d’une fonction support de première importance, et y attirer les meilleurs talents dans le futur.
Role of Social Factors affecting the Development of University Football
Authors: Ali Raza  , Muhammad Tahir Nazeer  , Prof. Wu Hao
Published: March 2021

Background: Football is known as the world's No. 1 sport and has always been loved by the majority of young people. The development of football on campus also has a long history and an extensive positive influence. It is recognized as a sport with good exercise value. With the increasingly close connection between football and social life, the development of university football is inevitably affected by many social factors. Through the analysis of the macro-development environment and development status of university football, it discusses the social factors affecting the development of university football from various aspects such as social systems, traditional ideas, and values. Method: Employing literature review, logical analysis, discussion with players, and experts interview methods, the athletes and coaches of university football teams were visited and investigated. Based on the guidance of players and coaches this paper summarizes the present situation of the football players of Pakistan with detailed data. Conclusion: The development of University Football faces the double lag of hardware and software facilities, and the competent supervision department of the state cooperate insufficient execution, weak University Football culture atmosphere, etc. are all bad factors that restrict and affect the development of University Football in our country.
ВИЗНАЧЕННЯ ХАРЧОВИХ БАРВНИКІВ У ГАЗОВАНИХ НАПОЯХ
Authors: SAVCHUK T. , KORMOSH ZH. , KOROLCHUK S.
Published: March 2021

Мета. Дослідження та ідентифікація харчових барвників у газованих безалкогольних напоях вітчизняних виробників.
Методика. Для дослідження та ідентифікації харчових барвників у безалкогольних напоях використовували метод тонкошарової хроматографії. Для експерименту використовували: пластинки для ТШХ Sorbfil (ТУ26-11-17-89), підкладка – алюмінієва фольга, сорбент – широкопористий силікагель марки СТХ-1А товщиною 90-120 мкм, різнотовщиність шару сорбенту на одній пластинці ± 5 мкм, зв’язуюча речовина – крохмаль; камери для хроматографування; калібрований капіляр або мікрошприц; хімічні стакани. Реактиви: контрольні розчини барвників; забарвлені розчини аналізованих газованих напоїв; розчинники (рухома фаза) система А: н-пропанол 100 см3, етилацетат 30 см3, вода 30 см3, аміак 1 см3 і система Б: оцтова кислота 20 см3, ізобутан 50 см3, вода 20 см3.
Результати. Для експерименту використовували такі газовані безалкогольні напої: «Mirinda» (orange) виробник «PepsiCo», «Фрутс» (оранж), Isotonic, «Соковинка» (вишня) виробник «Карпатські мінеральні води», «Чамбо» виробник «Біола». Дослідження проводили за такою схемою: пластинка №1 - «Mirinda» (orange) – визначення у складі наявності барвника Е110 (жовтий «сонячний захід»); пластинка №2 - «Фрутс» (оранж) – визначення у складі наявності барвника Е102 (тартразин); пластинка №3 – Isotonic – визначення у складі наявності барвника Е132 (індигокармін); пластинка №4 – «Соковинка» (вишня) – визначення у складі наявності Е124 (понсо 4R); пластинка №5 – «Чамбо» – визначення у складі наявності Е142 (зелений S). У результаті дослідження методом тонкошарової хроматографії виявили, що води «Мірінда», «Фрутс» та «Isotonic» містять у складі барвники: Е110, Е102 та Е132. Вода «Соковинка» не містить у складі синтетичного барвника Е124, що свідчить про те, що забарвлення напою здійснюється шляхом додавання натуральних забарвлених речовин. Вода «Чамбо» також не містить визначуваного барвника Е142, а зеленого забарвлення напою надає суміш барвників Е110 та Е102.
Практична значимість. Запропонований нами метод визначення барвників, який застосовували у газованих напоях для визначення барвників Тартразину, Жовтий «Сонячний Захід», Понсо 4R може бути використаний для ідентифікації харчових барвників і в інших продуктах харчування, зокрема, цукерках.
Econet planning with help of GIS technology
Authors: Kolejka Jaromír , Pokorný Jan
Published: March 2021

Geoecological and recent land use data have been evaluated from different standpoints in order to select the existing and to allocate the missing areal and linear elements of the ecological stabilizing network (econet) in the landscape on the local level. The project discussed in this article has been based on the GIS application used for multilayer data processing and result presentation supporting the decision-making process in the econet completion.
Oronyms of Central European Mountains Divided by national boundaries
Authors: Jeník Jan
Published: March 2021

A lot of confusion is encountered in coarse-scale maps in atlases from English speaking countries as regards oronyms of the mountains situated at the edge of the Bohemian Massif. Political and administrative boundaries often cut these regions. There is no general rule: either only trans boundary oronyms spelled in randomly chosen language are shown, or national oronyms along the political boundaries are used. The oronyms belonging to the "Bohemian Forest" take a number of different forms; in the "Ore Mountains" mostly the German name "Erzgebirge" is used. In the region along the Czech/German/Polish boundary the transboundary oronym "Sudetes" - in either of its four languague forms - is used.
COVID-19 Vaccination Efficacy and Safety Literature Review
Authors: Halim Michael
Published: March 2021

Since the emergency of the novel coronavirus disease (COVID-19) that is caused by SARS-Cov-2 in 2019, researchers have been on the move to find solutions to mitigate the spread of the virus. Various control measures have been put in place by governments under guidelines and recommendations of key global agencies with the world health organization (WHO) leading in providing information to help fight the pandemic. Multi-agency research efforts have been geared towards developing vaccines for active immunization to prevent COVID-19 infection. This paper is geared towards providing a detailed review and analysis of developments of the current vaccines in terms of safety and efficacy. Approaches that have been taken by different researchers and their findings are the subject of this work. Based on the mechanism by which a vaccine protects an individual against COVID-19 infection, it has been found that the already rolled out vaccines are mRNA (Pfizer and Moderna) and vector (Astrazeneca) vaccine structured. There is also China's Sinovac vaccine which has been in place for the past few years. The four vaccines reviewed here are administered in two doses some days apart. Currently, no vaccine has a safety threat and the efficacies are 95% for COVID-19 mRNA vaccine BNT162b2 (Pfizer), 94.1% for mRNA-1273 vaccine (Moderna), 70.4%forChAdOx1 nCoV-19 vaccine / AZD1222 (AstraZeneca) vaccine and 78% for sinovac respectively. Findings of this paper show that other vaccines are awaiting clinical roll out for trials. Even though these efficacies imply that the vaccines offer significant protection against the infection, further research and evaluation should go on to achieve higher efficacies while addressing any safety concerns that may go beyond local and systemic reactions that occur on patients after vaccination. This study concludes that even with the protection of the present vaccines, individuals must continue wearing personal protective equipment (PPEs) such as masks.
Hepatocyte-Specific Hepatocyte Nuclear Factor 4 Alpha (HNF4) Deletion Decreases Resting Energy Expenditure by Disrupting Lipid and Carbohydrate Homeostasis
Authors: Huck Ian , Morris E. Matthew , Thyfault John , Apte Udayan
Published: March 2021

Hepatocyte nuclear factor 4 alpha (HNF4) is required for hepatocyte differentiation and regulates expression of genes involved in lipid and carbohydrate metabolism including those that control VLDL secretion and gluconeogenesis. Whereas previous studies have focused on specific genes regulated by HNF4 in metabolism, its overall role in whole-body energy utilization has not been studied. In this study, we used indirect calorimetry to determine the effect of hepatocyte-specific HNF4 deletion (HNF4-KO) in mice on whole-body energy expenditure (EE) and substrate utilization in fed, fasted, and high-fat diet (HFD) conditions. HNF4-KO had reduced resting EE during fed conditions and higher rates of carbohydrate oxidation with fasting. HNF4-KO mice exhibited decreased body mass caused by fat mass depletion despite no change in energy intake and evidence of positive energy balance. HNF4-KO mice were able to upregulate lipid oxidation during HFD, suggesting that their metabolic flexibility was intact. However, only hepatocyte-specific HNF4-KO mice exhibited significant reduction in basal metabolic rate and spontaneous activity during HFD. Consistent with previous studies, hepatic gene expression in HNF4-KO supports decreased gluconeogenesis and decreased VLDL export and hepatic -oxidation in HNF4-KO livers across all feeding conditions. Together, our data suggest that deletion of hepatic HNF4 increases dependence on dietary carbohydrates and endogenous lipids for energy during fed and fasted conditions by inhibiting hepatic gluconeogenesis, hepatic lipid export, and intestinal lipid absorption resulting in decreased whole-body energy expenditure. These data clarify the role of hepatic HNF4 on systemic metabolism and energy homeostasis.
CONSUMER PREFERENCES AS A BASIS FOR CREATING A BRAND POSITION FOR WINE PRODUCTS
Authors: Khamidova Olga Mikhailovna , Ulanovskaya Oksana Nikolaevna
Published: March 2021

The relevance of the article lies in focusing on the positioning factors when creating an attractive wine brand for the target audience. In other words, the creation of a more advantageous brand position of a product and / or product line in comparison with competitors’ products based on research on consumer preferences, perceptions and cultural and behavioral characteristics.
To achieve the goal of the article, the genesis of the terms was revealed — brand, branding and positioning; the concept of «brand position» was proposed for use in marketing of consumer goods, the needs for wine-making products at all levels of the pyramid of A. Maslou are considered; a marketing research of consumer preferences of the target audience was carried out.
The study revealed that in the global competitive market for mass production, communications and distribution, the brand of a product becomes a powerful tool that creates additional value and stability for products and firms.
Conservation Of Urban Forest In Tanzania: Community Attitudes Towards Njiro Forest, Arusha
Authors: Massawe Goodluck Peter , Marealle Wilfred Njama , Liseki Stephen David , Camerini Giuseppe
Published: March 2021

Understanding community attitudes towards urban forests is of great importance since these attitudes are inherently linked to the long-term sustainability of urban forests management and conservation. We analysed the attitudes of the local community towards the Njiro forest (Arusha, Tanzania) which is managed and used as an experimental beekeeping area by TAWIRI (Tanzania Wildlife Research Institute). Data collection was done between September-October 2018 involving a sample of 163 randomly selected respondents. A semi-structured questionnaire was used to collect the data. Quantitative data were analysed through Statistical Packages for Social Sciences (SPSS). Chi-square tests and contingency tables were used to determine whether there was a significant difference between the expected frequencies and the observed frequencies in one or more categories. Possible influences coming from sociological and demographic factors such as age, gender, education level, occupation were assessed. The majority of the respondents declared to gain ecological benefits from the forest. A significantly larger group of older respondents in comparison with the younger ones (p<0.05) declared to face problems coming from the forest (stray dogs, robbers, illegal waste disposal). Males showed to be more interested in practising beekeeping than females (p<0.05). Respondents with a primary education level were more prone to express agreement with the adopted management strategies in comparison with respondents with higher education (p<0.001). In conclusion, the great majority of respondents declared to support the conservation of Njiro forest, however, employed respondents and females were more positive regarding the hypothesis of abolishing the forest (p<0.05). In order to improve management strategies and support the long-term conservation of the forest, respondents recommended strengthening the protection of the forest by fencing it, providing environmental education to the surrounding community, reinforcing the cooperation with the local community and planting new trees to improve the health of the forest ecosystem.