bluuebunny/crossref_metadata_2025 huggingface dataset:
Evolvability: filling the explanatory gap between adaptedness and the long-term mathematical conception of fitness
Authors: Bourrat Pierrick , Deaven Katie , Villegas Cristina
Published: July 2024

The new foundation for the propensity interpretation of fitness (PIF), developed by Pence and Ramsey (Br J Philos Sci 64:851–881, 2013), describes fitness as a probability distribution that encompasses all possible daughter populations to which the organism may give rise, including daughter populations in which traits might change and the possible environments that members of the daughter populations might encounter. This long-term definition of fitness is general enough to avoid counterexamples faced by previous mathematical conceptions of PIF. However, there seem to be downsides to its generality: the ecological role of fitness involves describing the degree of adaptedness between an organism and the specific environment it inhabits. When all possible changes in traits and all possible environments that a daughter population may encounter are included in the concept, it becomes difficult to see how fitness can fulfill this role. In this paper, we argue that this is a feature of Pence and Ramsey’s view rather than a bug: long-term fitness accommodates evolvability considerations, which concern the role that variation plays in evolutionary processes. Building on the foundations, we show that Pence and Ramsey’s fitness—F—can be partitioned into fourths: adaptedness, robustness of adaptedness, and two facets of evolvability. Conceptualizing these last three components forces us to consider the role played by grains of description of both organisms and the environment when thinking about long-term fitness. They track the possibility that there could be a change in type in a daughter population as a way of responding to environmental challenges, or that the type persists in the face of novel environments. We argue that these components are just as salient as adaptedness for long-term fitness. Together, this decomposition of F provides a more accurate picture of the factors involved in long-term evolutionary success.
Iconic origins of language? An essay review of Steven Mithen’s The Language Puzzle (2024)
Authors: van Mazijk Corijn
Published: July 2024

This essay review explores Steven Mithen’s interdisciplinary approach to the origins and evolution of language in The Language Puzzle (2024). It focuses mainly on what I call his iconic vocal origins hypothesis. Mithen challenges the prevalent gestural origins hypothesis, suggesting instead that early prehistoric languages were predominantly vocal and iconic, with conventionalization – as characteristic of symbol use – emerging later. The Language Puzzle draws on research from archaeology, philosophy, computer science, developmental psychology, and many other fields, thus assembling a wealth of insights from various disciplines. While intriguing, Mithen’s suggestion that prehistoric languages may have relied on iconicity instead of conventionalization faces substantial problems, which are discussed in this review essay. In the final section, I also briefly review the important conclusion chapter of Mithen’s book, which contains an imaginative outline of how language evolved from the last common ancestor up until modern H. sapiens. My criticisms of the iconic vocal origins hypothesis notwithstanding, The Language Puzzle is a valuable resource for anyone interested in language evolution, and once again showcases Mithen’s wide-ranging expertise and masterful writing.
Pollutant Dispersion Around a Single Tall Building
Authors: Rich Tomos , Vanderwel Christina
Published: July 2024

An experiment was carried out using a scale model of a tall building, with the goal of investigating the role of individual buildings in the dispersion of air pollution. Pollutant dispersion around an isolated building with a height-to-length aspect ratio of 1.4 is investigated using simultaneous particle image velocimetry and planar laser induced fluorescence. Dye is released from a ground-level point source five building heights upstream of the tall building. It was found that in this case the scalar plume was dispersed laterally strongly by the building, but only slightly vertically. It is hypothesized that this is due to 94% of the plume impinging below the stagnation point on the front of the building and being drawn into the horseshoe vortex. We expect this fraction would be lower in a case in which the building is in an array of smaller buildings, and that this would lead to more vertical dispersion.
Relational Quantum Mechanics and Contextuality
Authors: Robson Calum
Published: July 2024

This paper discusses the question of stable facts in relational quantum mechanics (RQM). I examine how the approach to quantum logic in the consistent histories formalism can be used to clarify what infomation about a system can be shared between different observers. I suggest that the mathematical framework for Consistent Histories can and should be incorporated into RQM, whilst being clear on the interpretational differences between the two approaches. Finally I briefly discuss two related issues: the similarities and differences between special relativity and RQM and the recent Cross-Perspectival Links modification to RQM.
Deciphering China’s higher education outreach paradigm in Southeast Asia: can a neo-tributary perspective work?
Authors: Zhu Kejin , Yang Rui
Published: July 2024

China’s unprecedented economic rise has fueled scholarly debates about its mentality of power strategy. Pundits have approached China’s strategic objectives through its higher education outreach, with Confucius Institute expansion and international student recruitment as two mostly discussed pathways. Whereas their efforts have been largely oriented by Western lexicon including soft power and center-periphery dichotomy. China’s emerging engagements in higher education aid projects and partnerships, particularly along the Belt and Road, are rarely noticed. Adopting the Chinese history-based neo-tributary perspective as the theoretical lens, this study (re)conceptualizes China’s paradigm for global rise through its higher education export to Southeast Asia, encompassing language training, educational development assistance, student mobility, and institution/program partnerships. Data was collected from documentation, institutional data, and semi-structured interviews with 40 informants from Sino-Cambodian higher education programs. The results suggest that universities serve as a showcase for a more pragmatic Chinese exceptionalism, in which traditional Chinese worldview has been incorporated with scientific outward-looking Western ideals. A cultural recognition-seeking tactic has been experimented through telling stories of China’s attractive contemporary cultures and values in educational practices. China has relied more on utilizing higher education as a tool for short-lived economic incentives, diplomatic alliances, and image-building activities to yield quick returns. However, concrete higher education outreach practices remain scant. Neo-tributary perspective is helpful in systematically examining China’s power projection but still confined to its simplified presuppositions of Sino-centrism. It should integrate pluralistic concepts like tianxia and knowledge diplomacy to unveil China’s interactions with the ‘Global South’ and the ‘Global North’.
Middle school students’ career parental support and adolescent–parent career congruence: the mediating role of self-efficacy
Authors: Söner Osman , Gültekin Filiz
Published: July 2024

Social cognitive career theory accepts that an individual’s career journey occurs through the interaction of multiple factors. The career development process includes internal or external factors’ positive or negative effects. This study aims to examine the mediating role of career and talent development self-efficacy, which expresses the belief about a person’s ability, in the relationship between two variables related to parents (adolescent–parent career adaptation—career-related parental support), which is an important factor in the career development of secondary school students. The model was tested with data collected from 652 secondary school students. The results showed that career and ability self-efficacy had a partial mediating role between career-related parental support and adolescent–parent career adjustment. Suggestions are presented to increase adolescent–parent harmony.
Core functions, visitor friendliness and digitalisation: a comparative analysis of corporate museums’ performance
Authors: Dalle Nogare Chiara , Murzyn-Kupisz Monika
Published: July 2024

We exploit a rich dataset on Italian museums to investigate whether corporate museums’ service provision is quantitatively different from the provision by the rest of private museums and by the three different types of Italian publicly owned museums (whose classification is by organisational mode: traditional, autonomous, and outsourced). We consider service provision in the dimensions of core museum functions (research, collection management, dissemination) and visitor friendliness, and we also focus on digital services. We use count data models estimation methods and include controls referring to museums’ characteristics and contextual factors to account for possible confounding effects. Our analysis reveals that corporate museums do not provide more core services than other museums, as expected given the public good component of this category of services. Contrary to expectations, we find that corporate museums are not among the museums providing the largest number of services enhancing visitor friendliness. Finally, corporate museums provide more digital services than traditional public museums and private museums owned by churches, and not less than other museum types. We argue that this latter evidence may come from their interaction with the parent firm. Corporate museums’ higher levels of digitalisation may be seen as the effect of a knowledge spillover between the more profit-oriented business world and the non-profit cultural sector.
Design and evaluation of composite films for in situ synthesis and antibacterial activity of allicin vapour
Authors: Mašková Lucie , Závišová Lenka , Kašpar Ondřej , Knejzlík Zdeněk , Rimpelová Silvie , Tokárová Viola
Published: July 2024

Although allicin has potent antibiotic properties, its low stability, which is responsible for its persistent biological activity, has posed a significant challenge to its practical application in modern medicine. To harness the healing benefits of this phytochemical, known by humans for thousands of years, we propose a controlled in situ synthesis of allicin vapour near the site of infection. Considering the critical need for novel approaches to prevent pandemic scenarios caused by MDR bacteria, we suggest encapsulating and physically separating allicin precursors (substrate alliin and enzyme alliinase) in alginate-based films and spray-dried chitosan microparticles. The mechanical properties of the hydrogel films of various compositions were evaluated, as well as their ability to protect the encapsulated alliinase against thermal stress and control the overall rate of allicin release upon hydration. Furthermore, the non-contact antibacterial efficacy of free alliin/alliinase reaction mixture (aqueous solution) and three compartmentalised configurations, i.e. film-solution, film-particles, and double-film, were tested against selected bacterial strains, i.e. E. coli, S. epidermidis, and S. aureus. The results indicate that the formation of allicin vapour using the proposed compartmentalised systems addresses allicin’s stability issues and provides better control over the rate of allicin production. The observed antibacterial effect was comparable with directly formed allicin using higher initial amounts of both substances, which is given by diffusion limitations associated with encapsulation. These findings illustrate the potential of compartmentalised systems in developing nature-based wound dressings for infection prevention and promoting healing.
Influence of Structural Properties of Oleic Acid-Capped CdSe/ZnS Quantum Dots in the Detection of Hg2+ Ions
Authors: Ortiz Calderon Fredy Giovany , Gómez Pineros Brayan Stiven , McClenaghan Nathan D. , Granados-Oliveros Gilma
Published: July 2024

Oleic acid-capped CdSe/ZnS quantum dots (QDs) were used to investigate their photoluminescence (PL) response to Hg2+ ions as a function of the surface properties of QDs. Three distinctly-size CdSe/ZnS QDs were obtained by varying the molar ratio of shell precursors, which were characterized by X-ray diffraction (XRD), high-resolution transmission electron microscopy (HR-TEM), Fourier-Transform infrared (FT-IR), X-ray photoelectron spectroscopy (XPS), absorption spectroscopy, and time-resolved fluorescence spectroscopy. Results revealed the obtention of zinc blende nanocrystals with sizes ranging from 2.7 to 3.2 nm (± 0.5) and ZnS thickness between 0.3 and 1.0 monolayer (ML). The variation of the [S]/[Zn] molar ratio introduced chemical species that act as traps, affecting the PL properties differently. Depending on the thickness of the shell and chemical speciation on surface, Hg2+ ions could induce quenching or enhancement of PL. Detection of mercury ions was evaluated in terms of Stern-Volmer equation, where the limit of detection (LOD) for the PL quenching system was 11.2 nM, while for the PL enhancing systems were 8.98 nM and 10.7 nM. Results demonstrate the performance of oleic acid-capped CdSe/ZnS QDs to detect Hg2+ and their capacity to turn the PL on/off depending on surface properties.
Sleep Problems and Gambling Disorder: Cross-Sectional Relationships in a Young Cohort
Authors: Austin Holly A. , Chamberlain Samuel R. , Grant Jon E. , Baldwin David S.
Published: July 2024

Aims

To investigate the potential association between gambling disorder and symptoms of sleep problems (including insomnia and excessive daytime sleepiness). It was hypothesised that, compared to controls, individuals with gambling disorder would have significantly greater disturbance of sleep, as indicated by increased scores in: (1) sleep items on the Hamilton Anxiety Rating Scale (HAM-A) and Hamilton Rating Scale for Depression (HAM-D); (2) total score on the HAM-A and HAM-D; and (3) the Epworth Sleepiness Scale (ESS).

Methods

Secondary analysis of previously published data from 152 young adults, aged 18–29 years. Individuals were stratified into three groups: controls, those at risk of gambling disorder, and those with gambling disorder. One-way ANOVAs with post-hoc tests were conducted to determine whether groups differed significantly in sleep item scores and total scores of the HAM-A and HAM-D, and the ESS.

Results

HAM-D scale insomnia item scores were significantly higher in the disorder group, when compared to controls, this being particularly marked for middle and late insomnia. The HAM-A item score indicated significantly worse sleep quality in the disorder group, compared to at risk and control groups. Total HAM-A and HAM-D scores were significantly higher in the disorder group, but ESS scores did not differ significantly.

Conclusion

Measures of disruptions in sleep were significantly higher in gambling disorder than controls. Anxiety and depressive symptom severity was also significantly higher in the gambling disorder group. Further research could have implications for identification and treatment of sleep disorders and psychiatric comorbidities in gambling disorder.
Classification of Time–Frequency Maps of Guided Waves Using Foreground Extraction
Authors: Guerra-Bravo Esteban , Baltazar Arturo , Balvantin Antonio , Aranda-Sanchez Jorge I.
Published: July 2024

Guided waves propagating in mechanical structures have proved to be an essential technique for applications, such as structural health monitoring. However, it is a well-known problem that when using non-stationary guided wave signals, dispersion, and high-order vibrational modes are excited, it becomes cumbersome to detect and identify relevant information. A typical method for the characterization of these non-stationary signals is based on time–frequency (TF) mapping techniques. This method produces 2D images, allowing the study of specific vibration modes and their evolution over time. However, this approach has low resolution, increases the size of the data, and introduces redundant

information, making it difficult to extract relevant features for their accurate identification and classification. This paper presents a method for identifying discontinuities by analyzing the data in the TF maps of Lamb wave signals. Singular Value Decomposition (SVD) for low-rank optimization and then perform foreground feature extraction on the maps were proposed. These foreground features are then analyzed using Principal Component Analysis (PCA). Unlike traditional PCA, which operates on vectorized images, our approach focuses on the correlation between coordinates within the maps. This modification enhances feature detection and enables the classification of discontinuities within the maps. To evaluate unsupervised clustering of the dimensionally reduced data obtained from PCA, we experimentally tested our method using broadband Lamb waves with various vibrational modes interacting with different types of discontinuity patterns in a thin aluminum plate. A Support Vector Machine (SVM) classifier was then implemented for classification. The results of the experimental data yielded good classification effectiveness within reasonably low computational time despite the large matrixes of the TF maps used.
The Changing Relationship Between Hobby Engagement and Substance Use in Young People: Latent Growth Modelling of the Add Health Cohort
Authors: Bone Jessica K. , Fancourt Daisy , Sonke Jill K. , Bu Feifei
Published: July 2024

Cross-sectional and some longitudinal evidence suggests doing hobbies can reduce substance use, but findings have been inconsistent, and whether associations differ across adolescence remains unclear. This study included 7454 Add Health participants (50% female, 77% White, age mean=14.95 and SD = 1.56). Participants were split into three groups, according to whether they were early (aged 11–14 at baseline), mid (aged 15–16), or late (aged 17–20) adolescents at baseline. The trajectories of binge drinking, marijuana, and tobacco use were analysed in latent growth models across Waves 1–5 (1994–2018). Concurrent associations between substance use and hobby engagement were tested at Waves 1–3 separately in the three age groups. Doing hobbies more frequently was associated with lower odds of binge drinking and marijuana and tobacco use in early adolescence. Although there was initially a similar protective association in mid and late adolescence, this had reversed by Wave 3 for binge drinking and marijuana use, when participants were young adults. This change in the association could be a result of differing social contexts, changes in peer influence, or an indication that creative hobbies are particularly beneficial. It could explain previous inconsistent findings and demonstrates the importance of considering developmental differences when investigating engagement in hobbies.
Chemical characterization of lithium based ceramics utilizing charged particle activation and ion beam techniques
Authors: Dasgupta S. , Datta J. , Reddy G. L. N. , Ghosh M. , Swain K. K.
Published: July 2024

Non-destructive methodologies using activation analysis and ion beam analysis techniques were optimized for the chemical characterization of ceramic materials, lithium titanate and lithium niobate, which have application in tritium breeding blanket. The analyses were carried out as a part of chemical quality control exercise. The atomic ratios of Li/Ti, Li/Nb were quantified by charged particle activation analysis using 13 MeV proton beam from variable energy cyclotron facility and particle induced gamma ray emission/Rutherford backscattering spectrometry using 3 MeV/2 MeV proton beam from 3MV tandem accelerator facility. The results of these different analytical methods are in good agreement, which established the applicability of these activation analysis and ion beam techniques for the chemical characterization of these ceramic materials.
Effect of substituted cobalt–chromium–iron oxides’ dissolution kinetics in oxidizing formulation on decontamination process
Authors: Balaji V. , Chandramohan P. , Puspalata Rajesh , Bera Santanu , Mohan T. V. Krishna
Published: July 2024

Removing radioactive corrosion products from Cr-containing iron oxides require a multi-step and multi-cycle decontamination process. The present article brings out the effect of divalent metal ion substitution on the release rate of chromium in the oxidative pre-treatment step. The non-stoichiometric cobalt chromium ferrites were synthesized, characterized and effect of Zn2+/Ni2+ substitution on the dissolution behavior was probed. The dissolution rates decreased with increasing the degree of inclusion and showed minima at ~ 0.4–0.6 atom% which is explained on the basis of lattice structure. It is concluded that the dissolution kinetics of native nickel–chromium ferrites in reactors increases with metal ion inclusion.
Thermal degradation of nanoporous Si-containing hybrid terpolymer
Authors: Sobiesiak Magdalena , Puziy Alexander M. , Poddubnaya Olga I. , Parcheta Monika
Published: July 2024

In this work development of structural and chemical properties of four nanoporous hybrid carbons has been presented. The carbons were synthesized by direct carbonization at 450, 600, 750 and 900 °C of the terpolymeric hybrid precursor composed of methacrylamide, divinylbenzene and trimethoxyvinylsilane and impregnated with sulfanilic acid (SA) as the surface modifier. The conditions of the carbonization process were set on the basis of the thermogravimetric analysis combined with FTIR analysis of the evolved gases (TGA-EGA). The use of SA contributed to the reduction of the carbonization temperature by about 100 °C and resulted in carbons with very uniform and bimodal porosity with the width range of about 1 and 14–28 nm. Spectral (ATR, Raman, XPS) and X-ray diffraction methods used to characterize the resulting carbon products allowed to define the gradual changes taking place in the morphological and chemical structure of the prepared materials. Cyclic and symmetrical structures of silicates species were gradually replaced by amorphous arrangements. At the same time, the increase in the sp2/sp3 carbon ratio from 1 to 65% proved progressive ordering and aromatization of the carbonized polymeric hybrid precursor. Some functional groups (e.g., N-containing) were built into carbon clusters forming pyridinic, pyrrolic and N-graphitic like structures, while others (e.g., carbonyls) were removed from the surface.
A0 mode Lamb wave propagation in a nonlinear medium and enhancement by topologically designed metasurfaces for material degradation monitoring
Authors: Liu Ze , Shan Shengbo , Cheng Li
Published: July 2024

This paper intends to provide an application example of using metamaterials for elastic wave manipulation inside a nonlinear waveguide. The concept of phase-gradient metasurfaces, in the form of artificially architectured structures/materials, is adopted in nonlinear-guided-wave-based structural health monitoring (SHM) systems. Specifically, the second harmonic lowest-order antisymmetric Lamb waves (2nd A0 waves), generated by the mutual interaction between primary symmetric (S) mode and antisymmetric (A) mode waves, show great promise for local incipient damage monitoring. However, the mixing strength is adversely affected by the wave beam divergence, which compromises the 2nd A0 wave generation, especially in the far field. To tackle this problem, a metasurface is designed to tactically enhance the 2nd A0 waves through manipulating the phases and amplitudes of both primary waves simultaneously. After theoretically revealing the features of the 2nd A0 wave generation in a weakly nonlinear plate, an inverse-design strategy based on topology optimization is employed to tailor-make the phase gradient while ensuring the high transmission of the primary waves, thus converting the diverging cylindrical waves into quasi-plane waves. The efficacy of the design is tested in a 2nd-A0-wave-based SHM system for material degradation monitoring. Results confirm that the manipulated S and A mode waves can propagate in a quasi-planar waveform after passing the surface-mounted metasurface. Changes in material properties inside a local region of the host plate can be sensitively captured through examining the variation of the 2nd A0 wave amplitude. The concept presented here not only showcases the potential of metamaterial-enhanced 2nd A0 waves for material degradation monitoring, but also illuminates the promising direction of metamaterial-aided SHM applications in nonlinear waveguides.
Numerical solution of FDE-IVPs by using fractional HBVMs: the fhbvm code
Authors: Brugnano Luigi , Gurioli Gianmarco , Iavernaro Felice
Published: July 2024

In this paper we describe the efficient numerical implementation of Fractional HBVMs, a class of methods recently introduced for solving systems of fractional differential equations. The reported arguments are implemented in the Matlab$$^{\copyright } $$

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code , which is made available on the web. An extensive experimentation of the code is reported, to give evidence of its effectiveness.
Atomic Force Microscopy of Transfer Film Development
Authors: Shaffer Kathryn E. , McCumiskey Edward J. , Krick Brandon A. , Ewin Jeffrey J. , Taylor Curtis R. , Junk Christopher P. , Blackman Gregory S. , Sawyer W. Gregory , Pitenis Angela A.
Published: July 2024

Atomic force microscopy (AFM) provides the opportunity to perform fundamental and mechanistic observations of complex, dynamic, and transient systems and ultimately link material microstructure and its evolution during tribological interactions. This investigation focuses on the evolution of a dynamic fluoropolymer tribofilm formed during sliding of polytetrafluoroethylene (PTFE) mixed with 5 wt% alpha-phase alumina particles against 304L stainless steel. Sliding was periodically interrupted for AFM topography scans. The average film roughness, the average friction coefficient, and polymer wear rate based on sample height recession were recorded as a function of increasing sliding cycles. Topographical maps suggested tribofilm nucleates in grooves of the steel countersample, spreads, and develops into a uniform film through sliding. Prominent nanoscale features were visible around 10,000 sliding cycles and thereafter. Scanning electron microscopy and energy-dispersive X-ray spectroscopy showed good correlations between these features and aluminum-rich domains, suggesting the presence of alumina particles on the surface.
Perseverance reduces whereas impulsivity increases the risk of reoffending
Authors: Hamatschek Marie Joséphine , Richter Melanie S. , Dahle Klaus-Peter
Published: July 2024

By law, every criminal verdict describes the norm violation in question. To date, the use of this information for prognostic purposes has been standardized only for sex offenses. This study presents a content-analytic approach to the material. A theory-based coding system allows for systematic tracing of the offender’s affective and regulatory processing during norm violation, targeting the entire action sequence: initial activation affect (positive vs. negative), impulsivity vs. intentionality, affect regulation, and coping with intention-implementation difficulties. In a sample of N = 304 males convicted of violent and/or sexual offenses, the processing variables were investigated with respect to (a) objective measurability, (b) relationships with established reoffending risk markers, and (c) their (incremental) performance in predicting reoffending. With respect to objectivity (a), the inter-rater agreement (n = 111) varied widely among the variables (intraclass correlation range 0.03–0.62). Regarding risk markers (b), significant associations were found with the Level of Service Inventory–Revised (LSI-R) subscales criminal history, alcohol/drugs, emotional/personal, and attitudes/orientation. The Crime Scene Behavior Risk Measure for sexual offenses (n = 106) correlated with psychological processing variables for the items multiple juvenile offenders and male victim. Two variables emerged as relevant for predicting recidivism (c): negatively motivated impulsivity predicted violent reoffending, while persistence when coping with implementation difficulties negatively predicted sexual and general reoffending. These relationships statistically mediated the predictive contribution of actuarial risk tools (LSI-R/crime scene behavior risk). Psychological processes during norm violation as reported in verdicts appear to represent underexploited information within risk assessment and beyond.
Object detection based deinterleaving of radar signals using deep learning for cognitive EW
Authors: Kocamış Mehmet Burak , Orduyılmaz Adnan , Taşcıoğlu Selçuk
Published: July 2024

In a real-world environment, multifunction radars (MFRs) pose major challenges to the electronic support system that is a part of cognitive electronic warfare. One of the main problems is deinterleaving of signals belonging to MFRs. The ability of MFRs to change their carrier frequency, pulse width, and pulse repetition interval (PRI) from pulse to pulse makes the deinterleaving task challenging. In this paper, an object detection based deinterleaving approach exploiting amplitude patterns caused by radar beam motions, which are determined based on radar antenna scan types, is proposed to deinterleave MFR signals. Amplitude patterns are created in two-dimensional images using amplitude (AMP) and time of arrival (TOA) parameters obtained from radar pulses. Deinterleaving is performed using a deep learning algorithm applied to these images. To the best of the authors’ knowledge, object detection based deinterleaving of radar signals using AMP-TOA images has not been considered so far. Contrary to the common approaches, in which searching for PRI patterns is required, amplitude patterns formed by the radar beam motions on the electronic support system are used in the proposed method. This enables robust identification of signals of MFRs having PRI, carrier frequency, and pulse width agility. With the proposed method, the intention of the radar, i.e., search or tracking, can be acquired in the deinterleaving stage, which ensures earlier situational awareness. The performance of the method is evaluated for varying number of radar signals from one to five through simulations, in which scenarios with missing pulses at different rates are considered. Simulation results demonstrate that, on the average, more than 0.98 mean average precision (mAP50) is achieved at 30% missing pulse rate. The performance of the method for search radar signals is slightly lower compared to that achieved for tracking radar signals due to the lower number of pulses received by the system. However, more than 0.93 AP50 is achieved for search radar signals in the presence of five radar signals with different missing pulse rates. Besides, real-time performance can be achieved using the proposed method on the GPU platform.
A Clinician’s Guide To Effectively Transitioning and Transferring Care For Pediatric Patients With Inflammatory Bowel Diseases From The Pediatric To Adult Gastroenterologist
Authors: Barry Jessica N. , Moses Jonathan D. , Kim Sandra C.
Published: July 2024

Purpose of Review

Transition of care for pediatric patients with inflammatory bowel diseases (IBD) is a continuous, dynamic process that takes place over several years with a coordinated approach executed by a multidisciplinary team. We review the concepts, tools, and research in effective transitioning and transfer of care for adolescent/young adult patients with IBD.

Recent Findings

Given the constraints within the healthcare system, effective transitioning can be challenging to implement in everyday clinical practice. Different barriers include resources and expertise in effective transitioning by pediatric and adult gastroenterology healthcare providers and the impact of non-gastrointestinal issues facing young adult patients who are learning to manage and coordinate all aspects of their medical care and health maintenance. Factors that facilitate successful care transitioning and transfer include structured transitioning programs, utilization of validated transition checklists, and IBD medical summaries.

Proactive transitioning by pediatric gastroenterologists in partnership with their emerging young adult patients with IBD leads to better clinical and psychosocial outcomes and ultimately, effective transfer of care to adult gastroenterology. By utilizing utilize comprehensive transition assessment tools and medical summaries in partnership with their patients, pediatric and adult gastroenterology teams can better prepare patients as they transfer to independent care and health maintenance.
An Expanded Narrative Review of Neurotransmitters on Alzheimer’s Disease: The Role of Therapeutic Interventions on Neurotransmission
Authors: Akyuz Enes , Arulsamy Alina , Aslan Feyza Sule , Sarisözen Bugra , Guney Beyzanur , Hekimoglu Abdulhekim , Yilmaz Beyza Nur , Retinasamy Thaarvena , Shaikh Mohd. Farooq
Published: July 2024

Alzheimer’s disease (AD) is a progressive neurodegenerative disease. The accumulation of amyloid-β (Aβ) plaques and tau neurofibrillary tangles are the key players responsible for the pathogenesis of the disease. The accumulation of Aβ plaques and tau affect the balance in chemical neurotransmitters in the brain. Thus, the current review examined the role of neurotransmitters in the pathogenesis of Alzheimer’s disease and discusses the alterations in the neurochemical activity and cross talk with their receptors and transporters. In the presence of Aβ plaques and neurofibrillary tangles, changes may occur in the expression of neuronal receptors which in turn triggers excessive release of glutamate into the synaptic cleft contributing to cell death and neuronal damage. The GABAergic system may also be affected by AD pathology in a similar way. In addition, decreased receptors in the cholinergic system and dysfunction in the dopamine neurotransmission of AD pathology may also contribute to the damage to cognitive function. Moreover, the presence of deficiencies in noradrenergic neurons within the locus coeruleus in AD suggests that noradrenergic stimulation could be useful in addressing its pathophysiology. The regulation of melatonin, known for its effectiveness in enhancing cognitive function and preventing Aβ accumulation, along with the involvement of the serotonergic system and histaminergic system in cognition and memory, becomes remarkable for promoting neurotransmission in AD. Additionally, nitric oxide and adenosine-based therapeutic approaches play a protective role in AD by preventing neuroinflammation. Overall, neurotransmitter-based therapeutic strategies emerge as pivotal for addressing neurotransmitter homeostasis and neurotransmission in the context of AD. This review discussed the potential for neurotransmitter-based drugs to be effective in slowing and correcting the neurodegenerative processes in AD by targeting the neurochemical imbalance in the brain. Therefore, neurotransmitter-based drugs could serve as a future therapeutic strategy to tackle AD.
High Risk Human Papillomavirus Prevalence in Patients with Hypopharynx Cancer of Northeast India: A Pilot Study
Authors: Krishnatreya Manigreeva , Rai Avdhesh Kumar , Bhattacharyya Mouchumee , Rahman Tashnin , Bhuyan Plabita , Sarma Anupam
Published: July 2024

Oncogenic viruses such as, Human papillomavirus (HPV) associated head and neck cancers have been considered to represent different etiological and pathological behaviour. This pilot study was conceived to investigate high risk HPV (hr-HPV) infection and its association with life style habits such as tobacco, alcohol consumption in patients with hypopharynx cancer from North –East India. A total of thirty four primary hypopharynx cancer biopsy specimens were collected. These samples were analysed for hr-HPV DNA using nested multiplex PCR (NMPCR). The lifestyle and dietary associated factors were collected through a self- designed questionnaire. The presence of hr-HPV was confirmed in 50% (n = 17) patients with hypopharynx cancer by nested multiplex PCR (NMPCR). Among hr-HPV positive cases, only HPV- 16 genotype was found. Significant association was observed between hr-HPV infections with alcohol consumption (p-0.025), alcohol with tobacco habit (p-0.01). Our study demonstrated that alcohol consumption, tobacco chewing may act as risk factors for hr-HPV infection in a subset of patients with hypopharynx cancer from the North-East region of India.
Extending the Life World: Phenomenological Triangulation Along Two Planes
Authors: Zlatev Jordan , Mouratidou Alexandra
Published: July 2024

Phenomenology is often mistakenly understood as both introspectionist and anthropocentric and thus as incapable of providing us with objective knowledge. While clearly wrong, such critiques force us to spell out how the life world that is given in human experience is in fact not anthropocentric and not incompatible with science. In this article we address this by adapting a recent proposal to extend the key methodological principle of cognitive semiotics, phenomenological triangulation, along two planes. The first is horizontal and concerns the dimensions of Self, Others and Things, as irreducibly interrelated dimensions of the life world. The second is vertical, and deals with the way phenomena are accessed: from a first-person (philosophical), second-person (empirical in a qualitative sense) and third-person (scientific in a quantitative sense) perspective. With each perspective, the life world becomes correspondingly extended beyond direct experience. It is thus neither static nor confining. We exemplify each step with corresponding research, also providing examples of how non-human animals and not only human beings may serve as Others, thus addressing the critique of anthropocentrism. We conclude by pointing out how, despite some theoretical differences, the focus on subjectivity and the explicit or implicit adoption of the principle of phenomenological triangulation can serve as common ground for cognitive semiotics and biosemiotics.
Prioritizing Indicators for Rapid Response in Global Health Security: A Bayesian Network Approach
Authors: Qazi Abroon , Simsekler Mecit Can Emre , Al-Mhdawi M. K. S.
Published: July 2024

This study explored a Bayesian belief networks (BBNs) approach, developing two distinct models for prioritizing the seven indicators related to the “rapid response to and mitigation of the spread of an epidemic” category within the context of both the specific category and the Global Health Security Index (GHS index). Utilizing data from the 2021 GHS index, the methodology involves rigorous preprocessing, the application of the augmented naive Bayes algorithm for structural learning, and k-fold cross-validation. Key findings show unique perspectives in both BBN models. In the mutual value of information analysis, “linking public health and security authorities” emerged as the key predictor for the “rapid response to and mitigation of the spread of an epidemic” category, while “emergency preparedness and response planning” assumed precedence for the GHS index. Sensitivity analysis highlighted the critical role of “emergency preparedness and response planning” and “linking public health and security authorities” in extreme performance states, with “access to communications infrastructure” and “trade and travel restrictions” exhibiting varied significance. The BBN models exhibit high predictive accuracy, achieving 83.3% and 82.3% accuracy for extreme states in “rapid response to and mitigation of the spread of an epidemic” and the GHS index, respectively. This study contributes to the literature on GHS by modeling the dependencies among various indicators of the rapid response dimension of the GHS index and highlighting their relative importance based on the mutual value of information and sensitivity analyses.
Training Session Models in Endurance Sports: A Norwegian Perspective on Best Practice Recommendations
Authors: Tønnessen Espen , Sandbakk Øyvind , Sandbakk Silvana Bucher , Seiler Stephen , Haugen Thomas
Published: July 2024

Background

Our scientific understanding of the mechanistic and practical connections between training session prescriptions, their execution by athletes, and adaptations over time in elite endurance sports remains limited. These connections are fundamental to the art and science of coaching.

Objective

By using successful Norwegian endurance coaches as key informants, the aim of this study is to describe and compare best practice session models across different exercise intensities in Olympic endurance sports.

Methods

Data collection was based on a four-step pragmatic qualitative study design, involving questionnaires, training logs from successful athletes, and in-depth and semi-structured interviews, followed by negotiation among researchers and coaches to assure our interpretations. Twelve successful and experienced male Norwegian coaches from biathlon, cross-country skiing, long-distance running, road cycling, rowing, speed skating, swimming, and triathlon were chosen as key informants. They had been responsible for the training of world-class endurance athletes who altogether have won > 370 medals in international championships.

Results

The duration of low-intensity training (LIT) sessions ranges from 30 min to 7 h across sports, mainly due to modality-specific constraints and load tolerance considerations. Cross-training accounts for a considerable part of LIT sessions in several sports. Moderate (MIT)- and high-intensity training (HIT) sessions are mainly conducted as intervals in specific modalities, but competitions also account for a large proportion of annual HIT in most sports. Interval sessions are characterized by a high accumulated volume, a progressive increase in intensity throughout the session, and a controlled, rather than exhaustive, execution approach. A clear trend towards shorter intervals and lower work: rest ratio with increasing intensity was observed. Overall, the analyzed sports implement considerably more MIT than HIT sessions across the annual cycle.

Conclusions

This study provides novel insights on quantitative and qualitative aspects of training session models across intensities employed by successful athletes in Olympic endurance sports. The interval training sessions revealed in this study are generally more voluminous, more controlled, and less exhaustive than most previous recommendations outlined in research literature.
Evaluation of Fe Content on the Fluidity of A356 Aluminum Alloy by New Fluidity Index
Authors: Durmuş Melek , Dispinar Derya , Gavgali Mehmet , Uslu Emin , Çolak Murat
Published: July 2024

Elements that are deliberately added to aluminum alloys or are incorporated into the alloy later depending on the production process affect the final product properties. In addition, liquid metal cleaning is important in minimizing undesirable elements. Considering the production process, one of the most harmful impurities that is likely to pass into the alloy via diffusion for aluminum is the element, Fe. It is known that this is due to the fact that although Fe is highly soluble in liquid aluminum and its alloys, it has very little solubility in solids. Depending on the Fe content, mechanical properties, porosity and fluidity properties are affected in aluminum alloys. In this study, stainless and carbon steel rods were dipped into the melt at 700 °C and 750 °C for 1, 2 and 5 h. Castings were performed before and after degassing. Four-channel fluidity mold with different section thickness was used in the trials. Additionally, microstructure characterization was performed under varying casting conditions. Fluidity Index was proposed which is a single value measured from all fluidity values in different sections. When the results were examined, it was determined that the diffusion material, holding time, casting temperature and liquid metal cleanliness had an effect on the fluidity. Due to the increase in diffusion time, a decrease in fluidity was observed in both carbon steel and stainless steel. It was found that fluidity was significantly reduced when using stainless steel.
A random elastoplastic framework of relationships between CBR and Young’s modulus for coarse-grained soils
Authors: Mendoza Cristhian , Paredes Jairo A.
Published: July 2024

The material quality indicator most commonly used for the quality of road materials is the California Bearing Ratio test (CBR). In addition, the CBR test provides a value commonly used to correlate with the resilient modulus (used in the design and analysis of pavement) due to its cost-effectiveness. This test measures soil resistance to penetration by a punch and compares it with the pressure measured in a standard material at the same penetration (2.5 mm or 5 mm). However, this test lacks physical explanations regarding mechanical behavior because the CBR value only compares soil penetration resistance with the pressure measured in a standard material. Another issue arises from the scattered results obtained from both equations and tests, highlighting the need for variability analysis of the CBR test to assess the effect of the different geotechnical variables on the CBR value. For this purpose, simulations using FEM (Finite Element Method) considering random soil parameters were performed for the CBR test. These FEMs included a linear elastic model and two failure criteria (Mohr–Coulomb and Drucker-Prager with a cap) and were prepared for granular soils. The evaluation shows that the increase or decrease in the CBR value is a function of the elastic modulus, yield stress, and friction angle. Moreover, the simulations expand the knowledge of the shearing mechanisms, generated stresses, displacement fields, and load sharing when the CBR test is made. From these results, a physical explanation of test results can be done. FEM simulations showed stress zones in conditions of elastic, compression, and shear behavior. These zones can explain the importance of elastic modulus, yielding stress, and friction angle in the CBR value. From numerical results, a new equation was proposed and compared with practical equations proposed by international standards and other sources to estimate the probability of underestimated values CBR according to the correlations used.
The digital trail of Ukraine’s 2022 refugee exodus
Authors: Wycoff Nathan , Singh Lisa O. , Arab Ali , Donato Katharine M. , Marahrens Helge
Published: July 2024

When the 2022 Russian full-scale invasion of Ukraine forced millions of people to leave their homes, officials worldwide scrambled to estimate the number of people who would seek refuge in their countries. There were a limited number of official tools in place to lean on to help determine this estimate. In this article, we investigate the possibility of using various publicly available organic (i.e. non-designed) data to predict forced movement from Ukraine early in the crisis. In particular, we establish Ukrainian-language insecurity and contextual indicators from multiple data sources, namely Google Trends, Twitter/X, local newspapers, the ACLED database, and the GDELT database. We compare the usefulness of these indicators in predicting forced migration into three neighboring countries: Poland, Slovakia, and Hungary. To minimize the challenge of temporal misalignment between the organic data and actual movement, we develop a lagging and aggregation framework. Findings reveal Google Trends variables are a robust leading indicator of observed forced migration for this conflict. While other indicators are less strong, they still capture shifts in forced migration flows, highlighting the potential for using publicly available organic data during emerging forced displacement crises.