bluuebunny/crossref_metadata_2025 huggingface dataset:
Underdiagnoses of Rickettsia in patients hospitalized with acute fever in Indonesia: Observational study results
Authors: Lokida Dewi , Hadi Usman , Lau Chuen-Yen , Kosasih Herman , Liang C. Jason , Rusli Musofa , Sudarmono Pratiwi , Lukman Nurhayati , Laras Kanti , Asdie Rizka Humardewayantie , Murniati Dewi , Susila I Made , Mubin Risna Halim , Karyana Muhammad , Gasem Muhammad Hussein , Alisjahbana Bachti
Published: February 2020

Background: Reports of human rickettsial infection in Indonesia are limited. This study sought to characterize the epidemiology of human rickettsioses amongst patients hospitalized with fever at 8 tertiary hospitals in Indonesia.Methods: Acute and convalescent blood from 975 hospitalized non-dengue patients was tested for rickettsia IgM and IgG by ELISA. Specimens from cases with seroconversion or increasing IgM and/or IgG titers were tested for rickettsia IgM and IgG by IFA and rickettsia genomes using primers for Rickettsia (R.) sp, R. typhi, and Orientia tsutsugamushi. Testing was performed retrospectively on stored specimens; results did not inform patient management.Results: Subject tested positive for R. typhi, R. rickettsia, and O. tsutsugamushi IgG antibodies were identified in 269/872 (30.8%), 36/634 (5.7%), and 19/504 (3.8%) of subjects, respectively. For the 103/975 (10.6%) non-dengue patients diagnosed with acute rickettsial infection, presenting symptoms included nausea (72%), headache (69%), vomiting (43%), lethargy (33%), anorexia (32%), arthralgia (30%), myalgia (28%), chills (28%), epigastric pain (28%), and rash (17%). No acute rickettsioses cases were suspected during hospitalization. Discharge diagnoses included typhoid fever (44), dengue fever (20), respiratory infections (7), leptospirosis (6), unknown fever (6), sepsis (5), hepatobiliary infections (3), UTI (3), and others (9). Fatalities occurred in 7 (6.8%) patients, mostly with co-morbidities.Conclusions: Rickettsial infections are consistently misdiagnosed, often as leptospirosis, dengue, or Salmonella typhi infection. Clinicians should include rickettsioses in their differential diagnosis of fever to guide empiric management; laboratories should support evaluation for rickettsial etiologies; and public policy should be implemented to reduce burden of disease.
Prevalence and determinants of virological failure, genetic diversity and drug resistance among people living with HIV in a minority area in China: a population-based study
Authors: Yuan Dan , Liu Meijing , Jia Peng , Li Yiping , Huang Yuling , Ye Li , Api Laze , Chen Maogang , Yao Liang , Wang Zixin , Liu Honglu , Liang Shu , Yang Shujuan
Published: February 2020

Background Liangshan Yi Autonomous Prefecture is one of the areas that most severely affected by human immunodeficiency virus (HIV) in China, and virological failure on antiretroviral therapy (ART) is serious in this area. Analyses of prevalence and determinants of ART failure, the genetic diversity and drug resistance among people living with HIV (PLWH) helps improve HIV treatment efficiency and prevent HIV transmission. Methods A total of 5157 PLWH were recruited from 2016 to 2017. The venous blood samples were subjected to RT-PCR, followed by sequencing of the HIV-1 pol gene, targeting the protease and reverse transcriptase fragments. HIV-1 diversity was analyzed using the DNAStar software and drug resistance mutations were analyzed using the Stanford University HIV Drug Resistance Database. Results A total of 2156 (41.81%) PLWH showed virological failure on ART. Males (ORm=1.25), heterosexual behaviors and drug injection (ORm=1.44) and mother to child transmission routes (ORm=1.58), the clinical stage of AIDS (ORm=1.35), having used illicit drugs and shared the needles (1-4 times: ORm=1.34; more than 5 times: ORm=1.52), having ever replaced ART regimen (ORm=1.48) increased the risk of virological failure among PLWH, while higher education lever (ORm=0.77) and ≥12 months on ART (12~36 months: ORm=0.72; ≥36 months: ORm=0.66) was associated with lower likelihood of virological failure. The data revealed that CRF07_BC (1508, 95.62%) were the most common strains, and the drug-resistant rate was 32.10% among PLWH with virological failure in this area. The high frequencies of drug resistance were found in EFV and NVP of NNRTIs, ABC, FTC and 3TC of NRTIs, and TPV/r in PIs. The most common mutations in NNRTIs, NRTIs and PIs were K103N/KN (64.69%), M184V/MV/I (36.29%) and Q58E/QE (4.93%), respectively. Conclusion We concluded that surveillance of virological failure, HIV-1 subtypes, and drug resistance to understand HIV-1 epidemiology and guide modification of ART guidelines, and target prevention and control strategies should be formatted to reduce the virological failure and drug resistance to promote viral suppression and prevent HIV-1 transmission.
The impacts of climate variability and human activities on streamflow change at basin scale
Authors: Zolfagharpour Farshid , Saghafian Bahram , Delavar Majid
Published: February 2020

Human activities (HA) and/or climate variability (CV) may be two major factors impacting natural flow regime (NFR). This study was conducted following two objectives. The first was to develop scenario-based hydrological modeling (SBHM) to disentangle the natural and human-induced impacts on flow regime. The second objective was to quantify the interaction between temperature and precipitation for the assessment of CV. To do so, six scenarios were defined to evaluate either the impact of HA, CV or both. Four major results were achieved: (1) the interaction between temperature and precipitation was more prominent in basin upstream areas, which reduced the streamflow by 9% in the entire simulation period; (2) when separating the effects of climatic and human factors, SBHM results in comparison with those of the climate elasticity analysis showed no significant differences; (3) HA were the main force driving the streamflow reduction in the study basin; (4) a 5 °C increase in air temperature in the future would lead to an increase of 1.6% in average annual streamflow, and 41% in peak runoff.
Comparison study of artificial intelligence method for short term groundwater level prediction in the northeast Gachsaran unconfined aquifer
Authors: Khedri Akbar , Kalantari Nasrollah , Vadiati Meysam
Published: February 2020

Accurate and reliable groundwater level prediction is an important issue in groundwater resource management. The objective of this research is to compare groundwater level prediction of several data-driven models for different prediction periods. Five different data-driven methods are compared to evaluate their performances to predict groundwater levels with 1-, 2- and 3-month lead times. The four quantitative standard statistical performance evaluation measures showed that while all models could provide acceptable predictions of groundwater level, the least square support vector machine (LSSVM) model was the most accurate. We developed a set of input combinations based on different levels of groundwater, total precipitation, average temperature and total evapotranspiration at monthly intervals. For each model, the antecedent inputs that included Ht-1, Ht-2, Ht-3, Tt, ETt, Pt, Pt-1 produced the best-fit model for 1-month lead time. The coefficient of determination (R2) and the root mean square error (RMSE) were calculated as 0.99%, 1.05 meters for the train data set, and 95%, 2.3 meters for the test data set, respectively. It was also demonstrated that many combinations the above-mentioned approaches could model groundwater levels for 1 and 2 months ahead appropriately, but for 3 months ahead the performance of the models was not satisfactory.
Juventude LGBTQI+ e a educação
Authors: Melo Cardoso Maria Heloisa , Garcia Feldens Dinamara , Lucini Marizete
Published: February 2020

A ordem normativa da escola, a disciplina e o controle da juventude, caracterizam a Pedagogia conservadora de Herbart, que ainda se mantém presente nas salas de aula brasileiras. Assim, este estudo tem o objetivo de abordar a noção de educação desenvolvida por Herbart, especificamente no que diz respeito ao governo das crianças, e a compreensão da condição da juventude LGBTQI+ sob o enfoque das políticas inclusivas. Para tanto, percorre-se uma discussão conceitual, desenvolvendo um estudo explicativo conduzido à luz das reflexões teóricas que, pela abrangência de origem e de foco, representam uma amostra variada da produção relativa à temática aqui apresentada. Os resultados obtidos evidenciam que a normalização da sexualidade é traduzida por regras sociais que influenciam a sociedade e todos que dela fazem parte, inclusive a escola. Este estudo aponta as políticas inclusivas como um possível caminho a percorrer, pela escola, para lidar com as diferenças no campo do gênero e da sexualidade.
As finalidades dos sistemas de educação brasileiros
Authors: Chizzotti Antonio
Published: February 2020

Este artigo analisa as finalidades da educação escolar. Os debates eleitorais expuseram, nas tensões da retórica, um conjunto discrepante de opiniões sobre as finalidades e as responsabilidades da educação escolar. Os discursos dos candidatos, dos educadores e dos pesquisadores e a participação de diferentes grupos sociais nas discussões sobre educação trouxeram para o espaço público a importância da educação escolar para a construção do projeto político do Estado brasileiro. Esta pesquisa sintetiza essas manifestações e faz uma análise bibliográfica das finalidades da educação para explicitar quais são as finalidades fundamentais dos sistemas de ensino nacionais. O artigo analisa as três finalidades prospectivas da educação definidas na Constituição Brasileira: o pleno desenvolvimento da pessoa, o preparo para o exercício da cidadania e a qualificação para o trabalho. São questões antigas, permanentes e sempre atuais nos sistemas nacionais de educação, historicamente fundamentais para construir-se um Estado e uma sociedade democrática, que garanta a Educação Básica universal para todos os brasileiros.
Romidepsin (FK228), A Histone Deacetylase Inhibitor and its Analogues in Cancer Chemotherapy
Authors: Pojani Eftiola , Barlocco Daniela
Published: February 2020

Background:

Human HDACs represent a group of enzymes able to modify histone and
non-histone proteins, which interact with DNA to generate chromatin. The correlation between irregular
covalent modification of histones and tumor development has been proved over the last decades.
Therefore, HDAC inhibitors are considered as potential drugs in cancer treatment. Romidepsin
(FK228), Belinostat (PXD-101), Vorinostat (SAHA), Panobinostat (LBH-589) and Chidamide were
approved by FDA as novel antitumor agents.

Objective:

The aim of this review article is to highlight the structure-activity relationships of several
FK228 analogues as HDAC inhibitors. In addition, the synergistic effects of a dual HDAC/PI3K
inhibition by some derivatives have been investigated.

Materials and Methods:

PubMed, MEDLINE, CAPLUS, SciFinder Scholar database were considered
by selecting articles which fulfilled the objectives of this review, dating from 2015 till present
time.

Results:

HDAC inhibitors have a significant role in cancer pathogenesis and evolution. Class I
HDAC isoforms are expressed in many tumor types, therefore, potent and selective Class I HDAC
inhibitors are of great interest as candidate therapeutic agents with limited side effects. By structurebased
optimization, several FK228 analogues [15 (FK-A5), 22, 23 and 26 (FK-A11)] were identified,
provided with significant activity against Class I HDAC enzymes and dose dependent antitumor
activity. Compound 26 was recognized as an interesting HDAC/PI3K dual inhibitor (IC50 against
p110α of 6.7 μM while for HDAC1 inhibitory activity IC50 was 0.64 nM).

Conclusion:

Romidepsin analogues HDAC inhibitors have been confirmed as useful anticancer
agents. In addition, dual HDAC/PI3K inhibition showed by some of them exhibited synergistic effects
in inducing apoptosis in human cancer cells. Further studies on FK228 analogues may positively
contribute to the availability of potent agents in tumor treatment.
3-Methyladenine Inhibits Procollagen-1 and Fibronectin Expression in Dermal Fibroblasts Independent of Autophagy
Authors: Jung Ji-yong , Choi Hyunjung , Son Eui-Dong , Kim Hyoung-june
Published: February 2020

Background:

Autophagy is deeply associated with aging, but little is known
about its association with the extracellular matrix (ECM). 3-methyladenine (3-MA) is a
commonly used autophagy inhibitor.

Objective:

We used this compound to investigate the role of autophagy in dermal ECM
protein synthesis.

Methods:

Normal human dermal fibroblasts (NHDFs) were treated with 3-MA for 24 h,
and mRNA encoding several ECM proteins was analyzed in addition to the protein
expression of procollagen-1 and fibronectin. Several phosphoinositide 3-kinase (PI3K)
inhibitors, an additional autophagy inhibitor, and small interfering RNA (siRNA) targeting
autophagy-related genes were additionally used to confirm the role of autophagy in ECM
synthesis.

Results:

Only 3-MA, but not other chemical compounds or autophagy-related genetargeting
siRNA, inhibited the transcription of procollagen-1 and fibronectin-encoding
genes. Further, 3-MA did not affect the activation of regulatory Smads, but inhibited the
interaction between Smad3 with p300. Moreover, 3-MA treatment increased the
phosphorylation of cAMP response element-binding protein (CREB); however, CREB
knock-down did not recover 3-MA-induced procollagen-1 and fibronectin
downregulation.

Conclusion:

We reveWe revealed that 3-MA might inhibit procollagen-1 and fibronectin
synthesis in an autophagy-independent manner by interfering with the binding between
Smad3 and p300. Therefore, 3-MA could be a candidate for the treatment of diseases
associated with the accumulation of ECM proteins.aled that 3-MA might inhibit procollagen-1 and fibronectin synthesis in an autophagy-independent manner by interfering with the binding between Smad3 and p300. Therefore, 3-MA could be a candidate for the treatment of diseases associated with the accumulation of ECM proteins.
Synthesis, Crystal Structure, Luminescence, and Nonlinear Optical Properties of 2-[(E)-[[4-[2-(4-Methoxyphenyl)ethynyl]phenyl] imino]methyl]-4- [(E)-phenyldiazenyl]phenol
Authors: Mohite Sagar Subhash , Patil-Deshmukh Aditya Babasaheb , Chavan Sanjay Shamrao
Published: February 2020

2-((E)-((4-((4-methoxyphenyl)ethynyl)phenyl)imino)methyl-4-((E)phenyldiazenyl)phenol (1)
have been synthesized and characterized. X-ray single crystal diffraction study of the compound 1
reveal a monoclinic structure. Room temperature luminescence is observed for 1 in CH2Cl2 solution
due to π* → π transition. The SHG efficiency by Kurtz powder technique indicating the compound 1
displayed the second harmonic generation (SHG) property.
An Effective Assembling of Novel Derivatives Containing Both Benzo[d]thiazole and Benzo[d]oxazole Rings
Authors: Mai Nguyen Thi Ngoc , Hoan Duong Quoc , Tuyet Vu Thi Anh , Thu Trang Tran Thi , Linh Duong Khanh , Huan Trinh Thi
Published: February 2020

A novel series of 5-(benzo[d]thiazol-2-yl)benzo[d]oxazole-based compounds was synthesized
in four linear steps in high yield from vanillin. Both benzo[d]thiazole and benzo[d]oxazole cyclizations
were assisted with a domestic microwave oven in about 4-8 minutes in which the yield of the
benzo[d]oxazole cyclization was up to 92%. Structures of the new synthesized compounds were elucidated
by spectral data.
Effect of Gamma Radiation to Cope with Post-harvest Losses and Nutritional Components in Guava (Psidium guajava L.)
Authors: Munir Neelma , Tahir Mehreen , Naz Shagufta
Published: February 2020

Background:

Guava (Psidium guajava L.) fruit is an important part of our diet and valuable for consumption as a source of healthy nutrients. Due to its perishable nature, it has a high decaying rate with an economic loss if not treated properly with suitable measures.

Objectives:

During the recent year, radiation technology gained popularity at a global level for treating foods to achieve better quality and long-lasting shelf life. Recent studies focus on the use of radiation treatment for guava to enhance its shelf life.

Methods:

Treatment of two local guava cultivars Gola and Surahi with gamma radiation at doses of 0.10 kGy, 0.25 kGy and 0.5 kGy and their effect was investigated on the microbial load and nutritional value.

Results:

Furthermore, the effect of gamma radiation on fruit shelf life, decay percentage, organoleptic qualities, and nutrient parameters including moisture, mineral ash, fat, fibre, protein and carbohydrate content was determined.

Conclusion:

Hence this study was helpful in optimizing the dose of gamma radiation for our commonly grown guava cultivars to enhance their shelf life.
Effects of Minor Compounds of Edible Oils on Human Health
Authors: Ghodsi Ramin , Nosrati Rahmat
Published: February 2020

Background:

Oils and fats are the densest sources of food energy among food groups.
Vegetable oils are constituted predominantly of triglycerides. Due to the importance of edible oils in
nutrition, food industry and human health, great attention has been paid to them in recent years.
Some minor bioactive constituents in oils include phospholipids, tocols, sterols, carotenoid, chlorophyll,
phenols, phylokynon and terpenes.

Objective:

The aim of the present study was to examine beneficial effects of minor compounds in edible oils on human health.
Results: Minor compounds of edible oils that we use daily can produce remarkable results in the prevention and treatment of various diseases like diabetes, inflammation, hypertension, cancer, allergy and central nervous system disorders due to their antimicrobial, anti-cancer, anti-viral, anti-oxidative, anti-inflammation, anti-mutagenic, hypolipidemic, and hypoglycemic properties, among others.

Conclusion:

The results of this study showed that the presence of beneficial minor compounds in oils could have significant impact on the prevention and treatment of various diseases. Therefore, the type of consumed oil can play an important role in human health.
Women in Cardiology: Role of Social Media in Advocacy
Authors: Patel Hena , Volgman Annabelle S.
Published: February 2020

:

Digital and social media have transformed the field of medicine. They are powerful tools
that academic and non-academic physicians and healthcare providers are using to influence others,
promote ideas, obtain knowledge, disseminate research and communicate with others. The history
of advocacy for women in medicine and the role of social media in influencing the choice of
women to choose Cardiology as a career and its role in advocacy for Women in Cardiology (WIC)
have been reviewed. It has changed the way cardiologists learn, educate, and interact with each
other. Social media has proven especially useful in advocating for WIC, but whether it can help
improve the numbers of female doctors going into Cardiology remains to be seen. In addition to encouraging
women to pursue cardiology, social media has drawn attention to key women’s rights
issues affecting practicing female cardiologists.
Therapeutic Effects of Curcumin against Bladder Cancer: A Review of Possible Molecular Pathways
Authors: Ashrafizadeh Milad , Yaribeygi Habib , Sahebkar Amirhossein
Published: February 2020

There are concerns about the increased incidence of cancer both in developing and developed countries.
In spite of recent progress in cancer therapy, this disease is still one of the leading causes of death worldwide.
Consequently, there have been rigorous attempts to improve cancer therapy by looking at nature as a rich
source of naturally occurring anti-tumor drugs. Curcumin is a well-known plant-derived polyphenol found in
turmeric. This compound has numerous pharmacological effects such as antioxidant, anti-inflammatory, antidiabetic
and anti-tumor properties. Curcumin is capable of suppressing the growth of a variety of cancer cells
including those of bladder cancer. Given the involvement of various signaling pathways such as PI3K, Akt,
mTOR and VEGF in the progression and malignancy of bladder cancer, and considering the potential of curcumin
in targeting signaling pathways, it seems that curcumin can be considered as a promising candidate in bladder
cancer therapy. In the present review, we describe the molecular signaling pathways through which curcumin
inhibits invasion and metastasis of bladder cancer cells.
Optimization of Pectin Extraction from Sweet Potato Peels Using Citric Acid and its Emulsifying Properties
Authors: Hamidon Nurul Hazirah , Abang Zaidel Dayang Norulfairuz , Mohd Jusoh Yanti Maslina
Published: February 2020

Background:

Pectin is a natural polysaccharide that has been used widely as a stabilizer
in food emulsion system.

Objective:

This study aimed to optimize the yield of pectin extracted from sweet potato residue and
investigate its emulsifying properties.

Methods:

Response surface methodology (RSM) has been utilized to investigate the pectin extracted
from sweet potato peels using citric acid as the extracting solvent. Investigation of the effect
of different extraction conditions namely temperature (°C), time (min) and solution pH on pectin
yield (%) were conducted. A Box-Benhken design with three levels of variation was used to optimize
the extraction conditions.

Results:

The optimal conditions determined were at temperature 76°C, time 64 min and pH 1.2 with 65.2% yield of pectin. The degree of esterification (DE) of the sweet potato pectin was determined using Fourier Transform Infrared (FTIR) Spectroscopy. The pectin is a high-methoxyl pectin with DE of 58.5%. Emulsifying properties of sweet potato pectin was investigated by measuring the zeta-potential, particle size and creaming index with addition of 0.4 and 1.0 wt % pectin to the emulsion.

Conclusion:

Extraction using citric acid could improve the pectin yield. Improved emulsion stability
was observed with the addition of the sweet potato pectin.
Capsella Bursa-pastoris (L.) Medic: An Insight into its Pharmacology, Expository Traditional Uses and Extensive Phytochemistry
Authors: Dar Mohd Akbar , Mir Reyaz Hassan , Mohi-ud-din Roohi , Mir Prince Ahad , Masoodi Mubashir Hussain , Akbar Seema , Mir Showkat Rasool , Sawhney Gifty
Published: February 2020

Introduction:

Capsella bursa-pastoris(L.) Medic is a traditional herb of the genus Capsella with long-standing Pakistan, India, Iraq, Cyprus, Turkey, Iran, Azarbayjan, Europe, Saudi Arabia, China and many other regions of Asian countries ethnomedical records. Preliminary studies from the animal model have provided valuable scientiﬁc evidence for its use, also the novel bioactive compounds.

Aim:

This review aims to summarize the ethnopharmacology, selected scientiﬁc evidence on the pharmacological properties and phytochemistry of C. bursa-pastoris(L.) Medic over the past 38 years while identifying potential areas of further development of this herb as an economical adjunct.

Methods:

The review covers literature pertaining to the evidence based on ethnopharmacology, therapeutic potential, and phytochemistry of C. bursa-pastoris(L.) Medic spanning from 1980 to 2018 available on Non-English journals and English/Non-English- MS worldwide accepted scientiﬁc databases via electronic search (Elsevier, Google Scholar, PubMed, Scopus, Springer, Web of Science, Wiley online library) and Ph.D. thesis databases (e.g., CKNI-China, JAIRO-Japan, Shodhganga-India, Myto-Malaysia, etc.)

Result:

Evidence suggests that the extracts and some compounds from. bursa-pastoris(L.) Medic
possessantimicrobial, anticancer, anti-inflammatory, smooth muscle contraction, infertility, antioxidant,
cardiovascular, sedative, hepatoprotective and acetylcholinesterase inhibitor properties. C.
bursa-pastoris, besides having pharmacological profile has an acceptable nutritional value also due
to its novel bioactive compounds such as phytosterols, phenolics, flavonoids, fatty acids, organic
acids, peptides and amino acids.

Conclusion:

Scientific evidence suggests that there is a strong pharmacological potential in developing
C. bursa-pastoris (L.) According to the Medic, it is a drug which is used in the treatment of
various disorders from antimicrobial to anticancer therapy. C. bursa-pastoris can be a rich source
for the advancement of novel drugs to treat many human diseases due to the wide range of chemical
constituents present in the plant. Various ethnomedical uses and phytochemicals responsible for
these uses have not been evaluated yet to their fullest.
Visualizing the stages of the educational research methodology into animation infographics for vocational students
Authors: Agustini Ketut , Santyadiputra Gede Saindra , Sugihartini Nyoman
Published: February 2020

Visualizing something abstract into a concrete object can help students improve their mastery of concepts in learning. The purpose of this study is to visualize the stages of the educational research methodology into an animation infographic media. The method used refers to the instructional development model. The target subjects of this study were students of informatics engineering education study program who had taken courses in educational research methodology. In order to get valid, practical, and effective media, several tests were carried out, such as formative evaluation and effectiveness testing with Hake formula. The results show that the dynamic infographic media produced has gone through expert judgment as follows. (1) Testing by content experts score 1 (very high), testing by the learning design experts scored 0.92 (very high), and testing by learning media experts scored 0.90 (very high). (2) The result obtained from the practicality testing is 86.5%, or it is included in the practical category. (3) The testing of the effectiveness of using the Hake formula obtained N-gain results of 0.8, which belongs to the effective category. It shows that animation infographic media produced is valid, practical, and effective to be used in improving the concept mastery of the stages of educational research methodology in informatics engineering education study program.
Effect of Cationic Surfactants on Properties of Zinc Oxide Nanoparticles Synthesized through Sol-gel Technique
Authors: Rauf Hwda Ghafur , Nodeh Hamid Rashidi , Aziz Madzlan , Kareem Sattar Ibrahim
Published: February 2020

Zinc oxide (ZnO) is an important metal oxide which participates in lots of applications, including gas sensors, catalysis, and optoelectronic devices. For nanostructured materials, agglomeration is problematic in the chemical production processes. In surfactant-free chemical reactions, aggregation occurs immediately as particles are generated. Therefore, the synthesis of controllable size nanoparticles is of great fundamental and technological interest. In the present study, the effect of cationic surfactants such as cetyltrimethylammonium bromide and benzalkonium chloride concentrations, on the optical properties, size, and morphology of ZnO nanoparticles synthesized through sol-gel method were studied. The characterizing tools were X-ray diffraction, Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), transmission electron microscopy (TEM), and ultraviolet-visible (UV-Vis-near-infrared) spectrophotometer. X-ray diffractogram confirmed the hexagonal (wurtzite structure) of ZnO. FTIR analyzed the presence of functional groups. The shape and size of the ZnO nanostructures were revealed by SEM and TEM. The band gap energy of the prepared ZnO samples was determined by UV-Vis spectrophotometer.
Revisiting Effective Communication Between Patients and Physicians: Cross-Sectional Questionnaire Study Comparing Text-Based Electronic Versus Face-to-Face Communication
Authors: Mirzaei Tala , Kashian Nicole
Published: February 2020

Background

Research has shown that text-based communication via telemedicine will continue to be a mode of communication that patients and physicians use in the future. However, very few studies have examined patients’ perspectives regarding the increased use of text-based communication versus face-to-face (FtF) communication.

Objective

This study aimed to understand and compare the potential differences in patients’ perceptions of communication effectiveness with their physicians through different modes of communication.

Methods

We conducted a web-based survey of 345 patients to explore the impact of different channels on effective communication and perceived health behavior and outcomes. We tested the impact of patients’ perceived communication and media effectiveness on their self-efficacy, communication satisfaction, and perceived health outcomes, separately for text-based information technology (IT)–mediated communication and FtF communication. Furthermore, we conducted a group comparison to identify significant differences across these 2 groups.

Results

We found no significant differences between patients’ perceptions of effective communication using either IT-mediated communication or FtF communication with their physicians. However, we found significant differences in patients’ perception of media effectiveness: patients perceived FtF communication to be a more favorable medium (P=.02). Interestingly, we found no significant difference in terms of benefits (P=.09) and success (P=.08) of IT-mediated communication versus FtF communication.

Conclusions

The results of this study imply that patients can achieve the same level of communication effectiveness with their physicians using IT-mediated communication as they would in comparable FtF interactions, but patients view FtF communication to be a more favorable medium than IT-mediated communication.
Computational architecture for collecting and integrating sleep data: proof concept (Preprint)
Authors: Lemos Rômulo Vitor Leão , de Araújo Luciano Vieira
Published: February 2020

BACKGROUND

Sleep is a fundamental function for life, and several approaches assist in its study. Ubiquitous monitoring offers parameters that assess sleep in its natural context. A common mobile data collection tool is the smartphone, and studies use the device’s native sensors to record information independently as well as provide users with alternatives to track the data that are captured.

OBJECTIVE

This research aims to develop a computational architecture for integration and analysis of data related to sleep, using data from mobile devices and environmental data, categorized by geolocation of the monitored individuals.

METHODS

We divided the architecture into the collection and integration modules. The collection module comprises an application for the Android operating system and was implemented using the Java language. In the integration module, we developed a PHP application responsible for receiving and handling the information from the collection module, storing the data, and orchestrating a series of calls to APIs to obtain data. Inside the server, there is also a Python script for requesting the Twitter API.

RESULTS

The tests performed in this work show some important information in data integration. Also, it is possible to conduct an in-depth analysis looking for information that addresses the study of sleep through mobile devices.

CONCLUSIONS

The proposed solution integrates data from different databases and generate a representation of sleep data from a macro perspective. Moreover, the proposal explores and analyzes data that previously were not used to represent, approximately, habits and behaviors of society. The results was positive and demonstrated that’s possible expand the data of sleep and generate insight on it.
Estudo na literatura indexada na base Scopus sobre acessibilidade na web
Authors: Guimarães Ítalo José Bastos , Araújo Wagner Junqueira de , Sousa Marckson Roberto Ferreira de
Published: February 2020

Se presenta una visión general de la producción científica internacional sobre la accesibilidad a la web a través de una encuesta sobre las principales áreas de conocimiento que publican acerca del tema dos de los países y universidades que tienen producción internacional relevante; se identifican los principales autores y medios donde éstos publican y se señalan los principales términos adoptados en la investigación realizada por ellos. La metodología empleada es descriptiva con un enfoque cuantitativo-cualitativo que se dividió en dos etapas, a saber: 1) encuesta sobre la producción internacional de accesibilidad en la web utilizando la base de datos Scopus como fuente, y 2) análisis de los principales conceptos. Los resultados mostraron que las principales áreas de conocimiento que producen publicaciones sobre el tema son informática, matemáticas y ciencias sociales. Estados Unidos está a la vanguardia de la producción científica en la materia y destacan España y el Reino Unido, Brasil ocupa el cuarto lugar. Los términos más utilizados son “web”, “accesibilidad” y la unión de las dos palabras “accesibilidad a la web”. Como resultado, se identificaron 2 448 autores diferentes, de los cuales 622 publicaron más de un texto, y se preparó un análisis sobre la coautoría en la red. Se sugiere que otros estudios utilicen un enfoque cualitativo que permita un mayor análisis de los conceptos principales e identifique cuáles son los más utilizados y verifique eventuales diferencias de comprensión sobre la temática.
Patologías asociadas al uso problemático de internet. Una revisión sistemática y metaanálisis en WOS y Scopus
Authors: Aznar Díaz Inmaculada , Kopecký Kamil , Romero Rodríguez José María , Cáceres Reche María Pilar , Trujillo Torres Juan Manuel
Published: February 2020

El uso problemático de internet (UPI) ha empezado a vincularse con la predisposición a padecer ciertas patologías que afectan la salud del ser humano. Este trabajo se propuso determinar las patologías asociadas al uso problemático de internet a partir de una revisión sistemática en Web of Science y Scopus, y analizar la incidencia del UPI en cada una de las patologías a través del metaanálisis. Así pues, se empleó una metodología de revisión sistemática con metaanálisis y se estableció una muestra final de 62 documentos. Entre los resultados destacan, como principales patologías asociadas al uso problemático de internet, el trastorno obsesivo-compulsivo, el abuso del alcohol, la depresión, el estrés, los trastornos del sueño, el déficit de atención y la hiperactividad y los trastornos alimenticios. Además, en la mayoría de estas patologías se estableció una significación estadística entre los grupos de control y los grupos con UPI. Finalmente, se muestra una panorámica general sobre los riesgos que conlleva el abuso de internet y la incidencia que presentan en la salud tanto física como mental.
Research tests of the Geoscan 101, the Geoscan 201 hardware-and-software complexes
Authors: Babashkin N.M. , Kadnichanskiy S.A. , Nekhin S.S.
Published: February 2020

During the recent decade, unmanned aerial vehicles (UAV) have been widely implemented in practice of the aerial survey for the purposes of inventory and mapping. This led to a variety of aerial survey results in terms of both aerial survey parameters and accuracy. Under these conditions, the task of assessing the accuracy of the final product obtained from aerial photographs with a UAV, for example, an orthophoto or a digital elevation model becomes urgent. The Federal State Budgetary Institution “Federal Scientific-Technical Center of Geodesy, Cartography and Spatial Data Infrastructure”, having a metrological service accredited by Rosstandart for the right to conduct metrological certification of measurement methods and metrological examination of documents, makes research tests of hardware and software for digital aerial survey and photogrammetric processing, which determine the values of metrological qualities of hardware and software complexes. The authors present the results of such tests as applied to hardware-andsoftware complexes based on the Geoscan 101 UAV and the Geoscan 201 UAV equipped with Sony DSC RX-1 and Sony DSC-RX1RM2 cameras. The accuracy indicators were obtained for orthophotos, digital surface and relief models, coordinates of targeted and non targeted points of land boundaries and building contours for all land categories and permitted uses of land parcels in accordance with the requirements of the Order of the Ministry of Economic Development of the Russia from 01.03. 2016 No 90.
О трёхмерных сетках Смоляка I
Authors: Добровольский Николай Николаевич , Горбачев Дмитрий Викторович , Иванов Валерий Иванович
Published: February 2020

Это первая статья из серии посвящённой сеткам Смоляка. Работа относится к аналитической теории чисел и в ней рассматриваются вопросы приложения теории чисел к задачам приближенного анализа. Рассмотрено понятие гиперболического параметра сеток с весами и аналог теоремы Бахвалова для гиперболического параметра сеток с весами и гиперболической дзета-функции сеток. В данной работе получены следующие результаты:1. доказана усиленная обобщённая теорема Бахвалова–Коробова для гиперболической дзета-функции трёхмерных сеток;2. подсчитано число узлов сетки Смоляка с учетом их кратности; число узлов c учетом их весов.3. подсчитано число узлов сетки Смоляка без учета их кратности;4. подсчитано число узлов сетки Смоляка c учетом их весов;5. найдена форма квадратурной формулы с сеткой Смоляка без кратных узлов и найдены явные формулы для весов этой квадратурной формулы. Показано, что количество узлов такой квадратурной формулы в 7 раз меньше, чем в случае формулы с кратными узлами.
Александр Васильевич Малышев и его исследования в теории чисел
Authors: Пачев Урусби Мухамедович , Подсыпанин Евгений Владимирович
Published: February 2020

Статья посвящена жизни и научно-педагогической деятельности известного математика, доктора физико-математических наук, профессора Александра Васильевича Малышева (1928–1993) в связи с 90-летием со дня его рождения. В ней сначала приводятся краткие биографические сведения из жизни А. В. Малышева. Основная часть нашей работы посвящена достижениям А. В. Малышева в теории чисел и его научно-педагогической и редакционно-издательской деятельности.
Identifying risk in production agriculture: an application of best-worst scaling
Authors: Atta Cosmos , Micheels Eric T.
Published: February 2020

The identification and management of risk plays a significant role in reducing variability in farm income. The choice of risk management tools and strategies may depend on several factors, including the perceived importance of the risk and the perceived level of control that producers have in managing the risk. This study uses data from a 2017 survey of grain and oilseed farmers in Saskatchewan and employs a count-based approach of best-worst scaling and latent class cluster analysis to examine their perception of the most important sources of risk and the factors that influence these perceptions. The results suggest production and marketing risks, such as variation in output prices, rainfall variability, and changes in input prices, are the most important risks to farmers. However, results also reveal heterogeneity in responses to these identified risks, suggesting that a multifaceted approach is needed by farmers to address risk.
PERANCANGAN ROBOT PENDORONG MENGGUNAKAN MOTOR STEPPER BERBASIS PLC DI PT.FDK INDONESIA
Authors: Gunardi Yudhi
Published: February 2020

Dunia industri elektronik tidak terlepas dari perkembangan mesin-mesin produksi. Semua proses tersebut tidak lepas dari peran sistem otomasi dengan pengerjaannya yang sangat akurat atau presisi dalam penempatan suatu benda, dan di tinjau dari sisi keamanan terhadap pengerjaannya atau baik bagi seorang operatornya. Sehingga dalam pemakaian alat bantu seperti Motor Stepper dengan sistem otomasi yang dikoordinasika dengan PLC (Programmable Logic Controller) dalam proses manufaktur bisa membantu kerja operator lebih efisien, menghemat biaya produksi. Pada Penelitian ini penulis akan mencoba merancang Robot Pendorong menggunakan Motor Stepper yang dikendalikan oleh PLC (Programmable Logic Controller). Kata Kunci : PLC, Motor Stepper
PERANCANGAN TRANSISI KOAXIAL KEWAVEGUIDE WG8
Authors: Ismanto Toni , Alaydrus Mudrik
Published: February 2020

Waveguide adalah struktur yang membimbing gelombang, seperti gelombang elektromagnetik atau gelombang suara. Ada berbagai jenis Waveguide untuk setiap jenis gelombang. Yang asli dan paling umum, artinya adalah pipa logam kosong digunakan untuk tujuan ini. Waveguides berbeda dalam geometri yang dapat membatasi energi dalam satu dimensi seperti di lempengan waveguides atau dua dimensi seperti dalam serat atau saluran waveguides. Selain itu, waveguides berbeda diperlukan untuk memandu frekuensi yang berbeda: membimbing serat optik laser (frekuensi tinggi) tidak akan memandu gelombang mikro (yang memiliki frekuensi yang jauh lebih rendah).Kata kunci: Waveguide, transisi koaxial, serat optik laser
STUDI ANALISIS PENGARUH INTERFERENSI CO-CHANNEL BCCH (BROADCAST CONTROL CHANNEL) TERHADAP KUALITAS SEL SISTEM JARINGAN DCS (DIGITAL CELLULAR SYSTEM) 1800
Authors: Budiyanto Setyo , Aldila Mariesa
Published: February 2020

Jumlah pelanggan telekomunikasi seluler yang terus mengalami perkembangan membuat berbagai operator mendirikan banyak BTS (Base Transceiver System) baru agar dapat melayani pelanggannya yang tersebar luas dimana-mana. Namun penambahan BTS bukanlah solusi total untuk mengimbangi jumlah pelanggan, masalah baru muncul akibat keterbatasan kanal frekuensi yang dimiliki oleh jaringan DCS 1800 sendiri. Karenanya digunakan konsep pengulangan frekuensi yang juga memungkinkan terjadinya interferensi co-BCCH sehingga target KPI yang dimiliki operator tidak tercapai.Pada penelitian ini dibahas mengenai kualitas sel di lokasi terjadi interferensi co-BCCH, hal ini menyebabkan kualitas sel tidak mencapai target KPI, ditemukan beberapa lokasi low level signal, dan TCH drop yang tinggi. Untuk mengatasi masalah tersebut kita menggunakan metode penelitian dari hasil drive test di lapangan dan selanjutnya dilakukan optimasi jaringan dengan cara frequency retune dan tilting antenna.Setelah dilakukan optimasi jaringan, dari hasil drive test after di lokasi interferensi dan juga dari KPI monitoring kita mendapatkan hasil semua indicator sudah mencapai KPI target.Kata kunci : DCS 1800, Interferensi Co-BCCH, Frekuensi, Optimasi.
RANCANG BANGUN PROTOTIPE ELEVATOR MENGGUNAKAN MICROCONTROLLER ARDUINO ATMEGA 328P
Authors: Adriansyah Andi , Hidyatama Oka
Published: February 2020

Sistem kendali elevator atau lift yang digunakan di gedung- gedung bertingkat umumnya menggunakan sistem kontrol PLC ( Programmable Logic Controller ). Dalam pembuatan prototype ini menggunakan alternatife lain untuk menggantikan peran PLC dalam mengendalikan proses Elevator atau Lift yang bekerja yaitu menggunakan Mikrokontroler Arduino UnoPrototype elevator atau lift ini berpedoman pada Lift sebenarnya, yang terdiri dari sensor di setiap lantai yang digunakan sebagai gerakan batas lift, beberapa tombol yang terletak baik di dalam sangkar lift ataupun di luar lift yang digunakan untuk memanggil lift ataupun melayani tujuan lantai, dua sensor mekanik untuk membatasi pergerakan pintu dan dua buah motor DC untuk menggerakan pintu lift dan juga untuk menggerakan lift keatas dan ke bawah. Sehingga melalui perangkat-perangkat tersebut menjadikan alat ini meyerupai dengan elevator atau lift sesungguhnya.Berdasarkan pengujian pada alat ini dapat disimpulkan, penggabungan antara hardware dan software menjadikan alat ini dapat berfungsi dengan baik, yaitu lift dapat naik ataupun turun, pintu lift dapat membuka ataupun menutup sesuai dengan perintah.Kata kunci : Mikrokontroller, Elevator, sistem kontrol
PEMODELAN SIMULASI KONTROL PADA SISTEM PENGOLAHAN AIR LIMBAH DENGAN MENGGUNAKAN PLC
Authors: Badaruddin Badaruddin , Saputra Endang
Published: February 2020

Dalam pengoperasian suatu peralatan atau mesin listrik kadang kita menemukan berbagai kendala, karena rumitnya proses pengaturan atau pengontrolannya. Maka dari itu untuk mendapatkan pengontrolan yang efisien, mudah, dan handal kita memerlukan suatu sistem kontrol otomatis, cepat dan akurat yaitu dengan menggunakan PLC (kepanjangan dari Programmable Logic Controller). Kelebihan dari alat ini adalah bersifat software, artinya fungsi control dapat dibuat dan dirubah dengan mudah melalui software atau program yang dikenakan padanya dengan menggunakan alat konsol atau komputer PC. Dengan kelebihan yang ada pada PLC ini mampu menggantikan sistem konvensional yang dipakai sebagai pengontrolan dari sistem pengolahan air limbah yang berada di Mabes TNI- AD. Dengan menggunakan kontroler PLC ini diharapkan dapat memudahkan para teknisi lapangan dalam memonitor cara kerja dan proses pengontrolan sistem pengolahan air limbah ini melalui layar monitor komputer. Dengan demikian jika suatu saat terjadi kerusakan atau kesalahan kita dapat dengan mudah melakukan pegecekan dan perbaikan melalui softwarenya. Kata kunci : PLC, Komputer PC, Software
PENERAPAN LEGO MINDSTROMS NXT FORKLIFT DAN CONVEYOR ROBOT UNTUK MENSORTIR BARANG MENGGUNAKAN SENSOR WARNA
Authors: Gunardi Yudhi , Saputro Eko
Published: February 2020

Robot Lego Mindstorms NXT adalah perangkat robot edukasional yang dirilis oleh Lego dimana dilengkapi NXT-G pemograman perangkat lunak atau opsional lab VIEW untuk LEGO MINDSTORMS. Penggunaan Mindstorms NXT membantu mempermudah pembuatan robot. Hal ini dikarenakan Mindstorms NXT menghilangkan kebutuhan untuk menyolder sirkuit dan menghilangkan kesulitan saat pemasangan motor. Dari latar belakang tersebut muncul pemikiran untuk membuat implementasi Lego Mindstroms NXT forklift dan conveyor robot untuk mensortir barang menggunakan sensor warna. Permasalahan akan dibatasi yaitu pembuatan prinsip kerja robot yaitu forklift berfungsi membawa bola ke conveyor robot kemudian disortir dengan sensor warna. Dari pembahasan tersebut dapat dibuat kesimpulan bahwa pengujian sensor yang digunakan, bekerja dengan baik, seperti sensor warna yang dapat mendeteksi warna-warna dan mensortirnya. Dan robot forklift juga dapat mengikuti garis serta membawa bola, selain itu conveyor robot juga mampu memberikan jalan pada bola serata membaca warna lalu mensortir bola-bola tersebut. Kata kunci : Lego Mindstorms NXT, Forklift, Conveyor
PERANCANGAN JARINGAN TRANSMISI GELOMBANG MIKRO PADA LINK SITE MRANGGEN 2 DENGAN SITE PUCANG GADING
Authors: Attamimi Said , Rachman Rachman
Published: February 2020

Perencanaan link budget merupakan salah satu bagian penting dari pemasangan jaringan transmisi microwave ini. Analisa yang dilakukan secara menyeluruh dari tahap awal penentuan lokasi, yaitu site Mranggen 2 dengan site Pucang Gading. Berdasarkan hasil pengamatan terhadap path profil untuk lintasan transmisi untuk menghubungkan site Mranggen 2 dengan site Pucang Gading diperoleh daerah fresnel dalam keadaan bersih dari halangan. Sehingga untuk perencanaan jaringan dapat dilaksanakan dengan optimal. Desain link budget akan dilaksanakan dalam microwave radio link point-to-point dari site Mranggen 2 dengan site Pucang Gading hasil dengan jarak 2.76 km, Menggunakan microwave RTN950 Frekuensi 23 GHz dengan antenna A23S06HAC berdiameter 0,6 meter, dengan pemancar daya 20 dBm dan menerima tingkat sinyal -31,65 dBm, Transmisi masih dapat bekerja dalam range KPI pada saat Power Transmit diturunkan ke 10 dBm up link Fade margin diperoleh 41,481 dB. saat down link diperoleh nilai Fade margin 41,870 dB.Keyword: microwave, link budget, Fade margin