bluuebunny/crossref_metadata_2025 huggingface dataset:
Minimizing seepage in irrigation canals in land reclamation systems via an innovative technology
Authors: Kalybekova Yessenkul , Zhu Kai , Nurlan Balgabaev , Seytassanov Ibragim , Ishangaliyev Timurlan , Yermek Auyelbek , Ismailova Gauharkul , Kurmanbek Zhanymhan , Issakov Yerlan , Dávid Lóránt Dénes
Published: August 2023

The escalating demand for water and the impact of climate change are posing significant challenges to global water scarcity and agricultural policies. The aim of this research is to investigate the factors influencing water losses in irrigation systems and provide recommendations to minimize such losses. The research methodology includes conducting studies to identify the factors causing water losses through evaporation and seepage from irrigation canals in the Kazakh part of the Ile River basin. The research results are theoretically substantiated, and a series of field studies are carried out at the inter-farm canal experimental site in Almaty province. Based on the factors affecting evaporation and seepage losses in irrigation canals, a new design of irrigation canal made from geocomposite material has been developed and introduced. This design helps to prevent water losses in inter-farm and on-farm canals of reclamation systems. The geocomposite polymer troughs have improved the technical level of irrigation systems and have enabled additional irrigation areas by increasing the efficiency of irrigation water use in land reclamation systems of Kazakhstan, thereby enhancing the efficiency factor of the irrigation network. Water seepage losses are influenced by several factors, including soil type, canal length, working flow, canal operation mode, canal condition, operation season, and wind impact. Under uniform canal operation mode, water losses are relatively small. However, intermittent modes and incomplete filling of the canal result in increased costs. The research findings indicate that for soils with a flow velocity between 0.10 and 0.30 M/s, water losses due to leakage and evaporation in constant-impact and intermittent-impact channels increase linearly. In intermittent-impact channels, irrigation water losses range from 33.7 to 40.1%. The introduction of geocomposite polymer troughs has the potential to enhance the technical level of irrigation systems by improving the efficiency of the irrigation network and enabling the addition of more irrigation plots. This research aims to reduce water losses in the irrigation canals of reclamation systems, optimize the management of water distribution in irrigation systems, enhance equipment measures, and introduce digital irrigation water metering technologies. Future studies propose the application of digital technologies to enhance irrigation water design and accounting as part of measures to minimize water losses in irrigation canals.
A cross-sectional assessment of PRRSV nucleic acid detection by RT-qPCR in serum, ear-vein blood swabs, nasal swabs, and oral swabs from weaning-age pigs under field conditions
Authors: Osemeke Onyekachukwu H. , Cezar Guilherme A. , Paiva Rodrigo C. , Moraes Daniel C. A. , Machado Isadora F. , Magalhaes Edison S. , Poeta Silva Ana Paula S. , Mil-Homens Mafalda , Peng Li , Jayaraman Swaminathan , Trevisan Giovani , Silva Gustavo S. , Gauger Phillip C. , Linhares Daniel C. L.
Published: August 2023

Introduction

The porcine reproductive and respiratory syndrome virus (PRRSV) continues to challenge swine production in the US and most parts of the world. Effective PRRSV surveillance in swine herds can be challenging, especially because the virus can persist and sustain a very low prevalence. Although weaning-age pigs are a strategic subpopulation in the surveillance of PRRSV in breeding herds, very few sample types have been validated and characterized for surveillance of this subpopulation. The objectives of this study, therefore, were to compare PRRSV RNA detection rates in serum, oral swabs (OS), nasal swabs (NS), ear-vein blood swabs (ES), and family oral fluids (FOF) obtained from weaning-age pigs and to assess the effect of litter-level pooling on the reverse transcription-quantitative polymerase chain reaction (RT-qPCR) detection of PRRSV RNA.

Methods

Three eligible PRRSV-positive herds in the Midwestern USA were selected for this study. 666 pigs across 55 litters were sampled for serum, NS, ES, OS, and FOF. RT-qPCR tests were done on these samples individually and on the litter-level pools of the swabs. Litter-level pools of each swab sample type were made by combining equal volumes of each swab taken from the pigs within a litter.

Results

Ninety-six piglets distributed across 22 litters were positive by PRRSV RT-qPCR on serum, 80 piglets distributed across 15 litters were positive on ES, 80 piglets distributed across 17 litters were positive on OS, and 72 piglets distributed across 14 litters were positive on NS. Cohen's kappa analyses showed near-perfect agreement between all paired ES, OS, NS, and serum comparisons (). The serum RT-qPCR cycle threshold values (Ct) strongly predicted PRRSV detection in swab samples. There was a ≥ 95% probability of PRRSV detection in ES-, OS-, and NS pools when the proportion of positive swab samples was ≥ 23%, ≥ 27%, and ≥ 26%, respectively.

Discussion

ES, NS, and OS can be used as surveillance samples for detecting PRRSV RNA by RT-qPCR in weaning-age pigs. The minimum number of piglets to be sampled by serum, ES, OS, and NS to be 95% confident of detecting ≥ 1 infected piglet when PRRSV prevalence is ≥ 10% is 30, 36, 36, and 40, respectively.
Soil Greenhouse Gas Emissions in Intercropped Systems Between Melon and Cowpea
Authors: Marcos-Pérez Mariano , Sánchez-Navarro Virginia , Zornoza Raúl
Published: August 2023

There is a need to assess alternative cropping systems for climate change mitigation. Hence, we aimed to evaluate if cowpea, a legume crop with high climate adaptability and active rhizodeposition, can reduce GHG emissions when intercropped with melon, if different intercropping patterns can affect these soil GHG emissions, and elucidate if GHG emissions are related by soil and crop properties. We compared a cowpea and melon monocultures with different melon-cowpea intercropping patterns during two crop cycles. The different melon-cowpea intercropping patterns were: row intercropping 1:1 (melon:cowpea), row intercropping 2:1 (melon:cowpea) and mixed intercropping (alternate melon/cowpea plants within the same row), receiving 30% less fertilizers than monocrops. Results showed that CO2emission rates were higher in the row 2:1 and row 1:1 intercropping systems compared to mixed intercropping, melon monocrop and cowpea monocrop, with the lowest emissions, likely due to the highest density of both plant species, which may stimulate microbial communities. Soil N2O emission rates were not affected by crop diversification, with very low values. Soil CO2and N2O emissions were not correlated with environmental factors, soil properties or crop yield and quality, suggesting that crop management and plant density and growth were the main factors controlling GHG emissions. When the GHG emissions were expressed on a crop production basis, the lowest values were observed in mixed intercropping, owing to higher crop production. However, the 1:1 and 2:1 cowpea intercropping systems, with the lowest overall crop production, showed higher values of GHG emissions per unit of product, compared to cowpea monocrop. Thus, intercropping systems, and mostly mixed intercropping, have the potential to contribute to sustainable agriculture by increasing land productivity, reducing the need for synthetic fertilizers and decreasing GHG emissions per unit of product. These results highlight the importance of considering both agricultural productivity and greenhouse gas emissions when designing and implementing intercropping systems.
Trajectory Optimization for the Nonholonomic Space Rover in Cluttered Environments Using Safe Convex Corridors
Authors: Li Yiqun , Liang Shaoqiang , Gao Jiahui , Chen Zong , Qiao Siyuan , Yin Zhouping
Published: August 2023

Due to the limitation of space rover onboard computing resources and energy, there is an urgent need for high-quality drive trajectories in complex environments, which can be provided by delicately designed motion optimization methods. The nonconvexity of the collision avoidance constraints poses a significant challenge to the optimization-based motion planning of nonholonomic vehicles, especially in unstructured cluttered environments. In this paper, a novel obstacle decomposition approach, which swiftly decomposes nonconvex obstacles into their constituent convex substructures while concurrently minimizing the proliferation of resultant subobstacles, is proposed. A safe convex corridor construction method is introduced to formulate the collision avoidance constraints. The numerical approximation methods are applied to transfer the resulting continuous motion optimization problem to a nonlinear programming problem (NLP). Simulation experiments are conducted to illustrate the feasibility and superiority of the proposed methods over the rectangle safe corridor method and the area method.
Experimental Study on the Ignition Characteristics of Scramjet Combustor with Tandem Cavities Using Micro-Pulse Detonation Engine
Authors: Kim Min-Su , Koo In-Hoi , Lee Keon-Hyeong , Lee Eun-Sung , Han Hyung-Seok , Jeong Seung-Min , Kim Holak , Choi Jeong-Yeol
Published: August 2023

This experimental investigation focused on the ignition and combustion characteristics of a tandem cavity-based scramjet combustor with side-by-side identical cavities. This study utilized the Pusan National University-direct connect scramjet combustor (PNU-DCSC), which was capable of simulating flight conditions at Mach number 4.0–5.0 and altitudes of 20–25 km using the vitiated air heater (VAH). The combustion tests were conducted under off-design point conditions corresponding to low inlet enthalpy. It is a condition in which self-ignition does not occur, and a micro pulse detonation engine (μPDE) ignitor is used. The results revealed that as the injection pressure of the gaseous hydrogen fuel (GH2) and the corresponding equivalence ratio increased, the combustion mode transitioned from the cavity-shear layer flame to the jet-wake flame. Furthermore, the measured wall static pressure profiles along the isolator and scramjet combustor indicated that the region of elevated pressure distribution caused by the shock train expanded upstream with higher equivalence ratios. When ignited from the secondary cavity, the combustion area did not extend to the primary cavity at lower equivalence ratios, while it expanded upstream faster with higher equivalence ratios. Therefore, the combustion characteristics of the tandem cavity were found to vary based on the overall equivalence ratio of the main fuel (GH2) and ignition position.
Explainable Artificial Intelligence (XAI): Concepts and Challenges in Healthcare
Authors: Hulsen Tim
Published: August 2023

Artificial Intelligence (AI) describes computer systems able to perform tasks that normally require human intelligence, such as visual perception, speech recognition, decision-making, and language translation. Examples of AI techniques are machine learning, neural networks, and deep learning. AI can be applied in many different areas, such as econometrics, biometry, e-commerce, and the automotive industry. In recent years, AI has found its way into healthcare as well, helping doctors make better decisions (“clinical decision support”), localizing tumors in magnetic resonance images, reading and analyzing reports written by radiologists and pathologists, and much more. However, AI has one big risk: it can be perceived as a “black box”, limiting trust in its reliability, which is a very big issue in an area in which a decision can mean life or death. As a result, the term Explainable Artificial Intelligence (XAI) has been gaining momentum. XAI tries to ensure that AI algorithms (and the resulting decisions) can be understood by humans. In this narrative review, we will have a look at some central concepts in XAI, describe several challenges around XAI in healthcare, and discuss whether it can really help healthcare to advance, for example, by increasing understanding and trust. Finally, alternatives to increase trust in AI are discussed, as well as future research possibilities in the area of XAI.
The Role of Peamaclein (Pru p 7) in PFAS Patients: An Italian Real-Life Study
Authors: Spalletti Marco , Lasala Valentina , Cameli Paolo , Bergantini Laura , Saletti Marco , Beltrami Valerio , Bargagli Elena , d’Alessandro Miriana
Published: August 2023

Pollen food allergy syndrome (PFAS) is an allergic reaction to specific foods in persons previously sensitised to pollen. The diagnosis of PFAS is made after taking a patient’s medical history and, in some cases, conducting skin tests and oral food tests with raw fruit or vegetables. The aim of the present study was to evaluate the role of Pru p 7 in patients suspected of having PFAS, who show clinical symptoms, positivity for Cup a 1 and negativity for Pru p 1 and Pru p 3. A total of 51 patients (mean age ± standard deviation, 33 ± 15 years; 20 men and 31 women), referred to the respiratory diseases and allergology units of Siena University Hospital, were enrolled retrospectively. All of them underwent allergy consultation and IgE evaluation for Cup a 1, Pru p 1 and Pru p 3 by immuno solid-phase allergen chip (ISAC). Pru p 7 assay was performed by the ImmunoCAP Phadia method in patients who tested positive for Cup a 1 and simultaneously negative for Pru p 1 and Pru p 3 by ISAC. The serum of 51 patients was tested for sensitisation to Pru p 7 by the ImmunoCAP Phadia method, and nine patients (17.65%) were found positive. An area under the receiver operating characteristic (AUROC) curve of 99.51% made it possible to distinguish PFAS and non-PFAS patients on the basis of Pru p 7 values. The best cut-off value was 0.16 kUA/l, which gave a 85.7% sensitivity and 97.73% specificity. This study helps define the role of Pru p 7 in PFAS patients sensitised to cypress pollen and testing negative to Pru p 1 and Pru p 3. A fast, easy and non-invasive diagnostic method is proposed to detect IgE specific for Pru p 7. Inclusion of Pru p 7 in the ISAC assay panel would facilitate the diagnosis of PFAS.
The Human Superorganism: Using Microbes for Freedom vs. Fear
Authors: Dietert Rodney R. , Dietert Janice M.
Published: August 2023

Balanced fear supports human rational decision-making and useful behavioral responses. In contrast, overwhelming, persistent, and unbalanced fear can paralyze the individual and result in heightened anxiety, lack of cognitive flexibility, fear-based public compliance and serious mental health issues. Psychobiotics research has established that a healthy microbiome is required for balanced fear and mental health protection via control of fear extinction. The recent COVID-19 pandemic featured daily, persistent, fear-of-a-single-contagion conditioning on a global scale paired with various behavioral mandates (e.g., lockdowns of the healthy, required wearing of face masks in many locations including schools, isolation from environmental microbes and each other through the closure of beaches and parks, and restrictions on social gatherings including access to family members in hospitals and senior-assisted facilities). Such mandates degraded the human microbiome and isolated us from each other and useful environmental microbes. It also ignored the historic role of secondary bacterial pathogens in pandemic deaths. This narrative review examines how the institutional promotion of fear-of-a-single-contagion, lack of balanced risk communication, and appalling disregard of our fundamental nature (as majority-microbial human superorganisms) resulted in problems rather than solutions. This review illustrates that government-public health-media promotion of pervasive fear and microbiome-degrading behaviors: (1) increased public compliance, (2) reduced cognitive flexibility, and (3) increased risk of mental health conditions. However, a portion of the general public chose a healthier path through their increased consumption of microbiome- and immune-supportive supplements and fermented foods during and after the COVID-19 pandemic. For a healthier future, public health must follow the lead of this population to ensure that human freedom, rather than paralyzing fear, dominates our future.
Benefits from Incorporating Virtual Reality in Pulmonary Rehabilitation of COPD Patients: A Systematic Review and Meta-Analysis
Authors: Patsaki Irini , Avgeri Vasiliki , Rigoulia Theodora , Zekis Theodoros , Koumantakis George A. , Grammatopoulou Eirini
Published: August 2023

Chronic Obstructive Pulmonary Disease (COPD) is characterized by irreversible airflow limitation. Patient participation in Pulmonary Rehabilitation (PR) programs has a beneficial effect on disease management, improving patients’ functional capacity and quality of life. As an alternative to traditional programs or as a complementary activity, the inclusion of virtual reality (VR) games is proposed. The aim of this research study was to investigate the effectiveness of incorporating VR in the pulmonary rehabilitation program of patients with COPD. A systematic literature search was performed for randomized controlled trials (RCTs) in the electronic databases Google Scholar, PubMed, and Pedro from January 2014 to March 2022. The search involved screening for studies examining the effectiveness of enhancing PR with VR. The PEDro (Physiotherapy Evidence Database) scale was chosen as the tool to assess the quality of studies. A meta-analysis was performed where possible. Six studies were included in this systematic review. The PEDro scale showed five studies of good methodological quality and one of fair quality. The variables examined were aerobic capacity for exercise, lung function, and anxiety and depression, with significant improvement regarding 6MWT and FEV1 (p < 0.05). There was variability noted in the VR applications and the proposed rehabilitation that the experimental groups followed. The application of VR is recommended for COPD patients, in combination with conventional PR. VR was found to be effective in increasing therapeutic effect and should be considered as a mean of increasing accessibility to PR. Therefore, further research, as well as additional RCTs regarding the effectiveness of VR in patients with COPD, seems necessary.
A Systematic Review of the Audiological Efficacy of Cartilage Conduction Hearing Aids and the Factors Influencing Their Clinical Application
Authors: Li Bei , Lee Sinyoung , Cao Zuwei , Koike Takuji , Joseph Robin , Brown Tamsin Holland , Zhao Fei
Published: August 2023

This systematic review evaluates the efficacy and benefit of cartilage conduction hearing aids (CC-HAs) and that factors that influence purchasing decisions. The hearing thresholds and functional gain following CC-HA wear were synthesised. A one-way analysis of variance compared the differences in the hearing thresholds and functional gain at individual frequencies and in patients with a variety of pathological changes. The synchronised aided hearing threshold and functional gain at 2.0 kHz were significantly better than at 0.5, 1.0, and 4.0 kHz. There was no significant difference in the synchronised unaided hearing thresholds across individual frequencies between 0.5 and 4.0 kHz. The synchronised functional gain in patients with atresia was significantly greater than in patients with aural atresia or stenosis and middle ear pathologies with normal ear canals. The acceptability of CC-HAs in terms of purchase decision is influenced by the condition of the external auditory meatus and severity of hearing loss, with the highest purchase rate seen in patients with aural atresia or stenosis. CC-HAs’ fitting procedure advantages and cosmetic considerations make these devices a viable and preferred choice for individuals with microtia and aural atresia. Additional research to evaluate the benefits towards emotional well-being is crucial to gain insights into the psychological impact of CC-HA use.
High-Rate Capability of LiNi0.9Mn0.1−xAlxO2 (NMA) (x = 0.01, 0.03, 0.05) as Cathode for Lithium-Ion Batteries
Authors: Noerochim Lukman , Gunawan Elsanti Anggraini , Pintowantoro Sungging , Nurdiansah Haniffudin , Adam Ariiq Dzurriat , Idris Nurul Hayati
Published: August 2023

LiNi0.9Mn0.1−xAlxO2 (NMA) (x = 0.01, 0.03, 0.05) cathodes were synthesized via the co-precipitation method and continued with the calcination process in a tube furnace at 750 °C under flowing oxygen gas for 12 h. X-ray diffraction (XRD) revealed a well-formed and high-purity phase with a hexagonal structure. LiNi0.9Mn0.07Al0.03O2 (NMA 973) had the best electrochemical performance with the lowest redox peak separation, the smallest charge transfer resistance (71.58 Ω cm−2), the highest initial specific discharge capacity of 172 mAh g−1 at 0.1C, and a capacity retention of 98% after 100 cycles. Under high current density at 1 C, NMA 973 had excellent specific discharge capacity compared to the other samples. The optimal content of Mn and Al elements is a crucial factor to obtain the best electrochemical performance of NMA. Therefore, NMA 973 is a promising candidate as a cathode for high-energy-density lithium-ion batteries.
Marine Flora of French Polynesia: An Updated List Using DNA Barcoding and Traditional Approaches
Authors: Vieira Christophe , Kim Myung Sook , N’Yeurt Antoine De Ramon , Payri Claude , D’Hondt Sofie , De Clerck Olivier , Zubia Mayalen
Published: August 2023

Located in the heart of the South Pacific Ocean, the French Polynesian islands represent a remarkable setting for biological colonization and diversification, because of their isolation. Our knowledge of this region’s biodiversity is nevertheless still incomplete for many groups of organisms. In the late 1990s and 2000s, a series of publications provided the first checklists of French Polynesian marine algae, including the Chlorophyta, Rhodophyta, Ochrophyta, and Cyanobacteria, established mostly on traditional morphology-based taxonomy. We initiated a project to systematically DNA barcode the marine flora of French Polynesia. Based on a large collection of ~2452 specimens, made between 2014 and 2023, across the five French Polynesian archipelagos, we re-assessed the marine floral species diversity (Alismatales, Cyanobacteria, Rhodophyta, Ochrophyta, Chlorophyta) using DNA barcoding in concert with morphology-based classification. We provide here a major revision of French Polynesian marine flora, with an updated listing of 702 species including 119 Chlorophyta, 169 Cyanobacteria, 92 Ochrophyta, 320 Rhodophyta, and 2 seagrass species—nearly a two-fold increase from previous estimates. This study significantly improves our knowledge of French Polynesian marine diversity and provides a valuable DNA barcode reference library for identification purposes and future taxonomic and conservation studies. A significant part of the diversity uncovered from French Polynesia corresponds to unidentified lineages, which will require careful future taxonomic investigation.
Using Constrained-Disorder Principle-Based Systems to Improve the Performance of Digital Twins in Biological Systems
Authors: Sigawi Tal , Ilan Yaron
Published: August 2023

Digital twins are computer programs that use real-world data to create simulations that predict the performance of processes, products, and systems. Digital twins may integrate artificial intelligence to improve their outputs. Models for dealing with uncertainties and noise are used to improve the accuracy of digital twins. Most currently used systems aim to reduce noise to improve their outputs. Nevertheless, biological systems are characterized by inherent variability, which is necessary for their proper function. The constrained-disorder principle defines living systems as having a disorder as part of their existence and proper operation while kept within dynamic boundaries. In the present paper, we review the role of noise in complex systems and its use in bioengineering. We describe the use of digital twins for medical applications and current methods for dealing with noise and uncertainties in modeling. The paper presents methods to improve the accuracy and effectiveness of digital twin systems by continuously implementing variability signatures while simultaneously reducing unwanted noise in their inputs and outputs. Accounting for the noisy internal and external environments of complex biological systems is necessary for the future design of improved, more accurate digital twins.
Development of a Microfluidic Chip System with Giant Magnetoresistance Sensor for High-Sensitivity Detection of Magnetic Nanoparticles in Biomedical Applications
Authors: Ger Tzong-Rong , Wu Pei-Sheng , Wang Wei-Jie , Chen Chiung-An , Abu Patricia Angela R. , Chen Shih-Lun
Published: August 2023

Magnetic nanoparticles (MNPs) have been widely utilized in the biomedical field for numerous years, offering several advantages such as exceptional biocompatibility and diverse applications in biology. However, the existing methods for quantifying magnetic labeled sample assays are scarce. This research presents a novel approach by developing a microfluidic chip system embedded with a giant magnetoresistance (GMR) sensor. The system successfully detects low concentrations of MNPs with magnetic particle velocities of 20 mm/s. The stray field generated by the magnetic subject flowing through the microchannel above the GMR sensor causes variations in the signals. The sensor’s output signals are appropriately amplified, filtered, and processed to provide valuable indications. The integration of the GMR microfluidic chip system demonstrates notable attributes, including affordability, speed, and user-friendly operation. Moreover, it exhibits a high detection sensitivity of 10 μg/μL for MNPs, achieved through optimizing the vertical magnetic field to 100 Oe and the horizontal magnetic field to 2 Oe. Additionally, the study examines magnetic labeled RAW264.7 cells. This quantitative detection of magnetic nanoparticles can have applications in DNA concentration detection, protein concentration detection, and other promising areas of research.
Gamma-Aminobutyric Acid and Glutamate Concentrations in the Striatum and Anterior Cingulate Cortex Not Found to Be Associated with Cognitive Flexibility
Authors: Stock Ann-Kathrin , Werner Annett , Kuntke Paul , Petasch Miriam-Sophie , Bensmann Wiebke , Zink Nicolas , Koyun Anna Helin , Quednow Boris B. , Beste Christian
Published: August 2023

Behavioral flexibility and goal-directed behavior heavily depend on fronto-striatal networks. Within these circuits, gamma-aminobutyric acid (GABA) and glutamate play an important role in (motor) response inhibition, but it has remained largely unclear whether they are also relevant for cognitive inhibition. We hence investigated the functional role of these transmitters for cognitive inhibition during cognitive flexibility. Healthy young adults performed two paradigms assessing different aspects of cognitive flexibility. Magnetic resonance spectroscopy (MRS) was used to quantify GABA+ and total glutamate/glutamine (Glx) levels in the striatum and anterior cingulate cortex (ACC) referenced to N-acetylaspartate (NAA). We observed typical task switching and backward inhibition effects, but striatal and ACC concentrations of GABA+/NAA and Glx/NAA were not associated with cognitive flexibility in a functionally relevant manner. The assumption of null effects was underpinned by Bayesian testing. These findings suggest that behavioral and cognitive inhibition are functionally distinct faculties, that depend on (at least partly) different brain structures and neurotransmitter systems. While previous studies consistently demonstrated that motor response inhibition is modulated by ACC and striatal GABA levels, our results suggest that the functionally distinct cognitive inhibition required for successful switching is not, or at least to a much lesser degree, modulated by these factors.
Examining Conjoint Behavioral Consultation to Support 2e-Autism Spectrum Disorder and Gifted Students in Preschool with Academic and Behavior Concerns
Authors: Kahveci Gül , Güneyli Ahmet
Published: August 2023

Conjoint behavioral consultation (CBC), as adjusted for 2e children with academic and behavioral difficulties, was the focus of this single-subject design study. Three young children from a preschool participated, together with their parents and teachers. Academic enablers for students—intervention, maintenance, and generalization phases; academic and behavioral competencies—intervention, maintenance, and generalization phases; and teachers’, parents’, and students’ perceptions of the intervention’s social validity data were collected among the outcome measures. Findings from multiple participant-related probes pointed to constructive improvements in the phases of intervention, maintenance for listening behavior, and improved on-task skill in intervention, maintenance, and generalization. Additionally, during the consultation, parents and teachers noted improvements in the outcomes of the target behavior such as rhythm keeping, picture–word matching, writing the pictured concept in Turkish, writing the pictured concept in English, short personal story writing, short personal story telling, and verbal math problem solving, and each stakeholder gave the intervention a grade for its social validity. Limitations, potential routes for future study, and implications for preschool CBC intervention are highlighted.
Age Weakens the Other-Race Effect among Han Subjects in Recognizing Own- and Other-Ethnicity Faces
Authors: Ma Jialin , Zhang Rui , Li Yongxin
Published: August 2023

The development and change in the other-race effect (ORE) in different age groups have always been a focus of researchers. Previous studies have mainly focused on the influence of maturity of life (from infancy to early adulthood) on the ORE, while few researchers have explored the ORE in older people. Therefore, this study used behavioral and eye movement techniques to explore the influence of age on the ORE and the visual scanning pattern of Han subjects recognizing own- and other-ethnicity faces. All participants were asked to complete a study-recognition task for faces, and the behavioral results showed that the ORE of elderly Han subjects was significantly lower than that of young Han subjects. The results of eye movement showed that there were significant differences in the visual scanning pattern of young subjects in recognizing the faces of individuals of their own ethnicity and other ethnicities, which were mainly reflected in the differences in looking at the nose and mouth, while the differences were reduced in the elderly subjects. The elderly subjects used similar scanning patterns to recognize the own- and other-ethnicity faces. This indicates that as age increases, the ORE of older people in recognizing faces of those from different ethnic groups becomes weaker, and elderly subjects have more similar visual scanning patterns in recognizing faces of their own and other ethnicities.
Face Blindness in Children and Current Interventions
Authors: Ma Weina , Xiao Zeyu , Wu Yannan , Zhang Xiaoxian , Zheng Dongwen , Lei Xue , Han Chengyang
Published: August 2023

Children with prosopagnosia, also known as face blindness, struggle to recognize the faces of acquaintances, which can have a negative impact on their social interactions and overall functioning. This paper reviews existing research on interventions for children with prosopagnosia, including compensatory and remedial strategies, and provides a summary and comparison of their effectiveness. However, despite the availability of these interventions, their effectiveness remains limited and constrained by various factors. The lack of a widely accepted treatment for children with prosopagnosia emphasizes the need for further research to improve intervention strategies. Last, three future research directions were proposed to improve interventions for prosopagnosia, including ecological approaches, the social challenges faced by children, and new potential intervention methods.
Renovation of Traditional Residential Buildings in Lijiang Based on AHP-QFD Methodology: A Case Study of the Wenzhi Village
Authors: Li Junjie , Peng Xiangbin , Li Chen , Luo Qiong , Peng Suna , Tang Huanchen , Tang Ruomei
Published: August 2023

The rapid growth of tourism has led to the transformation of numerous traditional dwellings in Yunnan into commercial lodgings, presenting a challenge to the preservation and inheritance of traditional culture. However, the existing renovation practices lack scientific data support and rely heavily on architects’ subjective designs. Thus, finding a scientific and stable approach to maintain the traditional residential characteristics becomes crucial. This study focuses on the renovation of Wenzhi villagers’ residences in Yunnan as a case study. It employs the innovative AHP-QFD design methodology to explore a more scientific and objective method for preserving and promoting the features of traditional dwellings in commercial renovations. Initially, the study assigns weights to the commercial renovation objectives—local traditional features, architectural functions, sustainability, and comfort—using the hierarchical analysis method (AHP). Subsequently, specific design features are derived from transformation requirements through interviews and questionnaires with residents, tourists, government officials, and experts. The innovation of this research lies in the application of AHP and QFD models to the innovative design of commercial renovations for traditional dwellings in Yunnan, resulting in a set of systematic and scientifically supported decision-making methods for renovating and preserving traditional buildings in the region. The study’s findings reveal that building geometry and dimensions, skilled traditional craftsmanship, and flexible and expandable solutions carry the highest weight in design. The application of the AHP-QFD model in commercial transformation design effectively balances the preservation of traditional culture and the pursuit of commercial value. It offers a feasible and innovative design solution for commercial transformations of traditional houses in the Yunnan region, ensuring the preservation of cultural heritage while enhancing commercial appeal.
Urinary 5-Hydroxyindolacetic Acid Measurements in Patients with Neuroendocrine Tumor-Related Carcinoid Syndrome: State of the Art
Authors: Rossi Roberta Elisa , Lavezzi Elisabetta , Jaafar Simona , Cristofolini Giacomo , Laffi Alice , Nappo Gennaro , Carrara Silvia , Bertuzzi Alexia Francesca , Uccella Silvia , Repici Alessandro , Zerbi Alessandro , Lania Andrea Gerardo Antonio
Published: August 2023

Carcinoid syndrome (CS), mostly associated with small intestinal neuroendocrine tumors (SI-NETs) or lung-related NETs, is characterized by symptoms related to hormonal secretion and long-term complications, including carcinoid heart disease (CHD), which is potentially life-threatening. In the early stages of the disease, symptoms are non-specific, which leads to delayed diagnoses. The availability of reliable tumor markers is crucial for a prompt diagnosis and proper management. This review summarizes available evidence on the role of 24 h urinary 5-hydroxyindolacetic acid (24u5HIAA), which is the urinary breakdown metabolite of serotonin, in the diagnosis/follow-up of NET-related CS, with a focus on its potential prognostic role, while eventually attempting to suggest a timeline for its measurement during the follow-up of NET patients. The use of 24u5HIAA is an established biomarker for the diagnosis of NETs with CS since it shows a sensibility and specificity of 100% and 85–90%, respectively. The downside of 24u5-HIAA is represented by the need for 24 h urine collection and the risk of confounding factors (foods and medication), which might lead to false positive/negative results. Moreover, 24u5HIAA is useful in the follow-up of NETs with CS since a shorter double time correlates to a higher risk of disease progression/disease-specific mortality. Furthermore, an elevation in 24u5-HIAA is correlated with a dismal prognosis because it is associated with an increased likelihood of CHD development and disease progression/mortality. Other potentially interesting biochemical markers have been proposed, including plasmatic 5HIAA, although further standardization and prospective studies are required to define their role in the management of NETs. Meanwhile, 24u5HIAA remains the most accurate CS biomarker.
The Behavior of Carbon Dots in Catalytic Reactions
Authors: Mokoloko Lerato L. , Forbes Roy P. , Coville Neil J.
Published: August 2023

Since their discovery in 2004, carbon dots (CDs), with particle sizes < 10 nm, have found use in various applications, mainly based on the material’s fluorescent properties. However, other potential uses of CDs remain relatively unexplored when compared to other carbon-based nanomaterials. In particular, the use of CDs as catalysts and as supports for use in catalytic reactions, is still in its infancy. Many studies have indicated the advantages of using CDs in catalysis, but there are difficulties associated with their stability, separation, and aggregation due to their small size. This small size does however allow for studying the interaction of small catalyst particles with small dimensional supports, including the inverse support interaction. However, recent studies have indicated that CDs are not stable under high temperature conditions (especially >250 °C; with and without a catalyst) suggesting that the CDs may agglomerate and transform under some reaction conditions. The agglomeration of the metal in a CD/metal catalyst, especially because of the CDs agglomeration and transformation at high temperature, is not always considered in studies using CDs as catalysts, as post-reaction analysis of a catalyst is not always undertaken. Further, it appears that under modest thermal reaction conditions, CDs can react with some metal ions to change their morphology, a reaction that relates to the metal reducibility. This review has thus been undertaken to indicate the advantages, as well as the limitations, of using CDs in catalytic studies. The various techniques that have been used to evaluate these issues is given, and some examples from the literature that highlight the use of CDs in catalysis are described.
Which Configuration of Photocatalytic Membrane Reactors Has a Major Potential to Be Used at an Industrial Level in Tertiary Sewage Wastewater Treatment?
Authors: Molinari Raffaele , Severino Angela , Lavorato Cristina , Argurio Pietro
Published: August 2023

Photocatalytic membrane reactors (PMRs) have been found to be very effective in the removal of organic pollutants (particularly recalcitrant compounds) from wastewater because they allow for the mineralization of organic pollutants to innocuous by-products, thus achieving high-quality treated water. Owing to the very high volumes of water involved, treated sewage wastewater could be reused if a very efficient tertiary stage, like a PMR, can be foreseen. In this review, the two main PMR configurations (photocatalytic membranes and slurry PMRs) were analyzed as requirements of a tertiary treatment of sewage wastewater considering six design and operational parameters of such plants: (i) continuous wastewater flow rate from the secondary stage; (ii) the self-control of the photodegradation rate related to wastewater chemical–physical parameters; (iii) ability to handle variations of wastewater concentration and flow rate; (iv) the control of the quality of treated wastewater; (v) low plant footprint; and (vi) easy maintenance. In this analysis, some characteristics of photocatalysis (which involves three phases: solid (the photocatalyst), liquid (the wastewater), and gas (oxygen or air)) and those of membranes (they can be produced using different materials and configurations, different processes (pressure-driven or not pressure-driven), etc.) were considered. The obtained results show that slurry PMRs seem more suitable than photocatalytic membranes for such applications. We believe this review can trigger a shift in research from the laboratory to industry in using photocatalytic membrane reactors.
Spatial Transcriptomic Technologies
Authors: Chen Tsai-Ying , You Li , Hardillo Jose Angelito U. , Chien Miao-Ping
Published: August 2023

Spatial transcriptomic technologies enable measurement of expression levels of genes systematically throughout tissue space, deepening our understanding of cellular organizations and interactions within tissues as well as illuminating biological insights in neuroscience, developmental biology and a range of diseases, including cancer. A variety of spatial technologies have been developed and/or commercialized, differing in spatial resolution, sensitivity, multiplexing capability, throughput and coverage. In this paper, we review key enabling spatial transcriptomic technologies and their applications as well as the perspective of the techniques and new emerging technologies that are developed to address current limitations of spatial methodologies. In addition, we describe how spatial transcriptomics data can be integrated with other omics modalities, complementing other methods in deciphering cellar interactions and phenotypes within tissues as well as providing novel insight into tissue organization.
Geopolymer Antimicrobial and Hydrophobic Modifications: A Review
Authors: Růžek Vojtěch , Novosád Jan , Buczkowska Katarzyna Ewa
Published: August 2023

The article summarizes the state of the art in increasing antimicrobial activity and hydrophobic properties of geopolymer materials. Geopolymers are inorganic polymers formed by polycondensation of aluminosilicate precursors in an alkaline environment and are considered a viable alternative to ordinary Portland cement-based materials, due to their improved mechanical properties, resistance to chemicals, resistance to high temperature, and lower carbon footprint. Like concrete, they are susceptible to microbially induced deterioration (corrosion), especially in a humid environment, primarily due to surface colonization by sulphur-oxidizing bacteria. This paper reviews various methods for hydrophobic or antimicrobial protection by the method of critical analysis of the literature and the results are discussed, along with potential applications of geopolymers with improved antimicrobial properties. Metal nanoparticles, despite their risks, along with PDMS and epoxy coatings, are the most investigated and effective materials for geopolymer protection. Additionally, future prospects, risks, and challenges for geopolymer research and protection against degradation are presented and discussed.
Ultrasound-Guided Occipital Nerve Blocks as Part of Multi-Modal Perioperative Analgesia in Pediatric Posterior Craniotomies: A Case Series
Authors: Gaelen Jordan I. , King Michael R. , Hajduk John , Vargas Angelica , Krodel David J. , Shah Ravi D. , Benzon Hubert A.
Published: August 2023

Various regional anesthetics have been used for postoperative analgesia for pediatric craniotomy. In this case series, we report retrospectively collected data on postoperative pain and analgesic use in 44 patients who received ultrasound-guided occipital nerve blocks in addition to intravenous analgesic agents for posterior craniotomy procedures. In the immediate post-anesthesia care unit, pain was rated as zero or well controlled in 77% of patients, with only 43% requiring intravenous or demand patient-controlled analgesia opioids. There were no block-related complications. Occipital nerve blocks may constitute a safe and effective component of multimodal analgesia in this population.
Postharvest Application of Novel Bio-Based Antifungal Composite Edible Coatings to Reduce Sour Rot and Quality Losses of ‘Valencia’ Oranges
Authors: Alvarez María , Pérez-Gago María , Taberner Verònica , Settier-Ramírez Laura , Martínez-Blay Victoria , Palou Lluís
Published: August 2023

Sour rot, caused by Geotrichum citri-aurantii, can produce significant postharvest losses of citrus fruits and, currently, cannot be effectively controlled by the postharvest fungicides registered in EU countries. Therefore, novel antifungal edible coatings (ECs) based on citrus pectin and beeswax and enriched with eugenol (EG), geraniol (GR), propolis extract (PR) or essential oils (EOs) from Satureja montana (SA), Cinnamomum zeylanicum (CI), or Commiphora myrrha (CM), were developed as alternatives to reduce sour rot and preserve the postharvest quality of ‘Valencia’ oranges. These natural agents were incorporated into the EC formulation and then applied to inoculated oranges. ECs enriched with EG (2–8 g/kg), GR (4 and 8 g/kg), PR (5–20 g/kg), and CM EO (15 g/kg) reduced disease incidence and severity by 75 to 100% compared to uncoated oranges after 20 days of incubation at 20 °C. ECs containing EG (8 g/kg), GR (4 g/kg), and PR (20 g/kg) reduced weight loss and retained firmness of oranges after 14 days of shelf life at 20 °C. Furthermore, all tested ECs maintained the fruit’s sensory and physicochemical quality. Overall, the EG-enriched pectin EC performed best, showing potential as a safe, bio-based alternative to conventional waxes containing synthetic fungicides for the management of citrus postharvest sour rot.
Influence of Growth Time and Temperature on Optical Characteristics and Surface Wetting in Nano-Crystalline Graphene Deposited by PECVD Directly on Silicon Dioxide
Authors: Lukša Algimantas , Bukauskas Virginijus , Nargelienė Viktorija , Treideris Marius , Talaikis Martynas , Selskis Algirdas , Suchodolskis Artūras , Šetkus Arūnas
Published: August 2023

Unique electronic properties of graphene offer highly interesting ways to manipulate the functional properties of surfaces and develop novel structures which are sensitive to physical and chemical interactions. Nano-crystalline graphene is frequently preferable to crystalline monolayer in detecting devices. In this work, nano-crystalline graphene layers were synthesized directly on SiO2/Si substrates by plasma-enhanced chemical vapour deposition (PECVD). The influence of the deposition time and temperature on the characteristics of the structures were studied. The optical properties and evaporation kinetics of pure water droplets were analysed, along with arrangement and composition of the grown layers. The nano-crystalline graphene layers grown at 500 °C were characterised by the refraction index 2.75 ± 0.35 and the normalised excess Gibbs free energy density 0.85/γwater 10−4 m, both being similar to those of the monolayer graphene. The changes in the refraction index and the excess Gibbs free energy were related to the parameters of the Raman spectra and a correlation with the technological variables were disclosed.