bluuebunny/crossref_metadata_2025 huggingface dataset:
Naučni doprinos istraživača Orijentalnog instituta
Authors: Gačanin Sabaheta
Published: December 2022

SCIENTIFIC CONTRIBUTION OF RESEARCHERS OF THE ORIENTAL INSTITUTE The historical and cultural memory of Bosnia and Herzegovina represents a complex mosaic that should be approached with conscientious and dedicated, both professional and scientific work. This is precisely the task of the researchers of the Oriental Institute, working on an objective picture of historical and cultural memory not only within today’s borders but also beyond. All research in terms of history and culture should offer an overview of historical events and cultural movements, while remembrance and correct interpretation of them should draw meaning and significance to Bosnians and Herzegovinans, in order to actualize them in the present with the aim of building the identity of the people living in Bosnia and Herzegovina and the region. All the researches of the past of scientific researchers of the Oriental Institute are interdisciplinary, scientifically based, precise, correct, and set up so that their results cannot be arbitrarily interpreted as it occasionally suits groups and individuals, who most often try to blur the truth with their demagogic statements and direct the attention of the scientific community and the cultural public to a peripheral and scientifically unfounded discourse. The 70th anniversary of the research work of the Oriental Institute is an example of a bright tradition of honorable and scientifically based work with a very significant contribution in terms of results that move the boundaries in the scientific fields that the researchers of the Oriental Institute deal with. Keywords: Oriental Institute, seventieth anniversary, scientific research, contribution and importance of basic research
Patrimonio del pasado para la comunidad del presente. Activación de un circuito turístico en la fortaleza El Coyparcito (Antofagasta de la Sierra, Puna meridional argentina)
Authors: Pérez Martina Inés , Grant Jennifer , Casanova Menéndez Martín Tomás , Gentile María Cecilia , Umaño Milva
Published: December 2022

El objetivo de este trabajo es presentar los resultados de la puesta en valor turística y activación patrimonial del sitio arqueológico El Coyparcito, el cual fue elegido por la comunidad para formar parte de los atractivos turísticos locales. Esta puesta en valor posibilitó la proyección social de nuestras investigaciones, dando lugar a una arqueología comprometida con quienes habitan los territorios en los cuales realizamos nuestro trabajo académico. Además, la estrategia elegida para la implementación del circuito, permitió minimizar el impacto sobre el sitio arqueológico, reforzar el vínculo comunidad-investigadores y democratizar el acceso a los resultados de investigaciones académicas. Generamos una propuesta que responde a las demandas comunitarias, y promueve la conservación y el uso sustentable del patrimonio arqueológico de la localidad, entendiendo que esa conservación debe ser el resultado de una gestión participativa, que dé lugar a discursos alternativos a la arqueología y garantice las condiciones para su legitimidad.
Manejos locales del patrimonio arqueológico: los casos de Jesús de Machaca e Ispaya Grande (La Paz, Bolivia)
Authors: Arano Romero Salvador
Published: December 2022

La patrimonialización se ha convertido, en muchos casos, en un medio para la obtención de recursos económicos a futuro, sobre todo ligados al turismo. Generalmente se acompaña de un análisis técnico llevado a cabo por profesionales entendidos en la materia. Si bien, las políticas nacionales apelan a la toma de decisiones de las poblaciones locales en relación al tema patrimonial el esquema se torna muchas veces vertical, donde la decisión final sobre lo que “es” patrimonio la detenta el profesional. De esta forma, el poblador local solamente es visto como la persona que otorga los permisos de investigación y su firma aval. Sin embargo, en los últimos años esta figura ha ido cambiando poco a poco, y las poblaciones locales han comenzado a darse cuenta del valor arqueológico que alberga su territorio. En el presente trabajo pretendo mostrar dos ejemplos de cómo se gestionó el trabajo arqueológico y de conservación gracias a las iniciativas de las poblaciones locales, específicamente del Municipio de Jesús de Machaca y de la comunidad de Ispaya Grande. A partir de las experiencias personales, entrevistas y charlas informales, trato de acercarme a las percepciones que tienen los pobladores locales sobre su pasado. Tanto en Jesús de Machaca como en Ispaya Grande existen diferentes preocupaciones, formas de llevar a cabo sus proyectos y sobre todo el valor que le otorgan los pobladores locales a los sitios arqueológicos, que van más allá de lo material.
Un emisario del Imperio de Japón en tierras paradójicas. Shimazaki Tōson en Argentina
Authors: Chiappe Ippolito Matías
Published: December 2022

El presente artículo aborda y analiza el diario de viajes que el escritor Shimazaki Tōson (1872-1943) escribió luego de su viaje por Sudamérica tras ser enviado por el Ministerio de Asuntos Exteriores del Imperio de Japón en 1936. Dicho texto, titulado Junrei (Peregrinaje) y escrito en 1937, consta de una estetización de los propósitos oficiales que habían motivado el viaje originalmente: en primer lugar, mitigar la imagen negativa que el Imperio había empezado a desarrollar en la comunidad internacional después de su expansión por Asia durante los primeros años de la década del treinta; segundo, establecer vínculos con la comunidad japonesa en Latinoamérica con la intención de que fueran instrumentales al gobierno en su proyecto expansionista. El artículo brindará ejemplos específicos que muestren dichos propósitos ocultos, pero también analizará la postura compleja que tomó Shimazaki ante ese discurso oficial.
La construcción identitaria de los personajes en “Silvio en El Rosedal”, de Julio Ramón Ribeyro, y en Calle de las Tiendas Oscuras, de Patrick Modiano
Authors: Coral González Manuel Alejandro
Published: December 2022

Este artículo interpreta la búsqueda de la identidad humana de los personajes creados por el cuentista peruano Julio Ramón Ribeyro en su cuento “Silvio en El Rosedal”, protagonizado por Silvio Lombardi, y por el novelista francés Patrick Modiano en su novela “Calle de las Tiendas Oscuras”, protagonizado por Guy Roland, a través de un análisis que se encuadra en la Tematología, a partir del cual se identifican y comparan temas y motivos literarios recurrentes en cada historia. Se postula una respuesta basada en el descubrimiento existencial de los personajes de estas obras literarias a una pregunta perpetua de la condición humana: ¿quién soy?
Homoeopathy and Renal Stone: An Evidence-Based Clinical Case Report of Non-Surgical Renal Stone Expulsion
Authors: Sardar Asif , Sarkar Subhasish
Published: December 2022

Renal stone is the most common urinary tract disease  found worldwide. The prevalence of renal stone  disease has increased considerably in the past few  decades. Changes in lifestyle, faulty diet, too much  psychological stress, and environmental factors are  possible predisposing factors. Some patients may be  asymptomatic or have atypical symptoms such as  vague abdominal pain. In contrast, others will have  more typical symptoms, such as acute abdominal or  flank pain, nausea, urinary urgency, or frequency.  The approach in conventional treatment gives no  permanent solution. Homoeopathic constitution  medicine treats the patient as a whole and seizes the  recurrence. This article illustrates a case report of  successful non-surgical expulsion of renal calculus  by homoeopathic medicine to show the potentiality  of homoeopathic medicines. 1,2
Homoeopathic Approach to Osteomyelitis with its Pathological Significance
Authors: Gupta Yogeshwari , Sharma Nitiksha , Gaur Pavitra
Published: December 2022

The article on osteomyelitis encapsulates the advance  study in catastrophic manner. The disease covering  both stages of infection either its periprosthetic – joint  infection and osteonecrosis condition of the bone. The  innovative understanding with appropriate procedure  is given in detail for progressive or uncontrolled  condition of the patient. An inflammatory or serious  condition of the bone and its structure in later stages  caused by pyogenic infection. Myobacteria is rarely  causing primary epiphyseal osteomyelitis. Medullary  superficial or localized osteomyelitis developed on  the various affecting site of bone. Subsequent bone  damage is the end result of this ailment. The sequelae  of osteomyelitis vary, depending on age at onset, site  of infection, presence or absence of foreign bodies,  and presence or absence of adjoining joint infection. An impaired vascularity occurs in the infected  area that results in dead space/bone and repeated  occurrence of bone infection may travel into the  irreversible form causing the person restless, although  suffering from great despodency. Altered immune  defense mechanism may result in exaggerating the  disease due to various abnormal conditions as in  diabetic wound or from insufficient blood supply. A  proper intervention simultaneously with diagnosis  by corresponding symptomatology and investigation  is essential to understand the pathological process  along with the case progression. 

Homoeopathy can aid the process of recovery  in cases of osteomyelitis when the best selected  similimum along with miasmatic inference taken into  consideration.
Propofol/Etomidate Induced and Isoflurane Maintained Anaesthesia in Dogs
Authors: Kantia Rajwanti G. , Jhala Shivrajsinh K. , Suthar Deepakkumar N. , Dabas Vijander Singh
Published: December 2022

Twenty-four clinical cases of dogs presented for surgical interventions requiring general anaesthesia were randomly divided into four groups (n=6) irrespective of age, breed, sex, body weight and surgical procedure. The animals of group I and II were first premedicated with atropine sulphate @ 0.02 mg/kg BW and butorphanol @ 0.2 mg/kg BW intramuscularly; whereas, atropine sulphate @ 0.02 mg/kg BW and buprenorphine @ 0.02 mg/kg BW was administered intramuscularly in animals of group III and IV, followed by diazepam @ 0.5 mg/kg BW intravenously in all the dogs. Induction of anaesthesia was achieved by intravenous administration of 1% propofol in group I and III and 0.2 % etomidate in group II and IV till effect. Dose sparing effect of pre-anaesthetic drugs, anaesthetic duration, viz., duration of surgery, duration of maintenance of anaesthesia, total duration of anaesthesia, recovery time and quality parameters, viz., quality of sedation, induction, maintenance anaesthesia and recovery were recorded. There was significant reduction in the induction dose of etomidate as well as recovery time as compared to propofol with both the pre-anaesthetic agents. The induction dose of propofol was also significantly reduced particularly with butorphanol than with buprenorphine. Duration of surgery, duration of maintenance of anaesthesia and total duration of anaesthesia were apparently lower in group IV than other three groups, but the duration of surgery only differed significantly due to variety of surgical procedures. Quality of sedation, induction, maintenance anaesthesia and recovery were found good to excellent in all the groups.
Efficiency of Multiple Ovulation and Embryo Transfer (MOET) in a Cattle Farm over a Period of Ten Years in Gujarat
Authors: Bhalodia Sanjay , Patel Hardik , Patel Deven , Patil Shivkumar , C.P. Devanand
Published: December 2022

The present study was conducted at Sabarmati Ashram Gaushala, Bidaj, Gujarat. A total of 427 donor animals were investigated over a ten-year period to assess the efficiency of Standard protocol of Multiple Ovulation and Embryo Transfer (MOET). Simultaneously a season wise and breed wise study was also conducted. Breeds studied were Gir, HF, HFCB, Jersey, JYCB, Red Sindhi and Sahiwal. Overall average number of embryos, average number of viable embryos, number of pregnancies and conception rate (%) were found to be 7.8, 4.8, 281 and 39.4, respectively.  The year-wise number of pregnancies and conception rates varied from 09 to 42, and 24.6% in 2009-10 to the highest 61.3% in 20014-15, respectively. Further, breed-wise results showed average viable embryo in different breeds as 2.8 in Gir, 4.1 in HF, 5.1 in HFCB, 6.3 in Jersey, 5.8 in JYCB, 3.7 in Red Sindhi and 6.6 in Sahiwal, with corresponding conception rates of 67.7. 34.6, 28.8, 53.1, 39.4, 47.1 and 36.4 %, respectively. A trend was observed that the efficiency of MOET programme was less during monsoon (31.2%) as compared to summer and winter (41.5 and 41.4%).
Electrocardiographic Abnormalities in Canine Dilated Cardiomyopathy and their Management
Authors: K Sesha Saikrishna , K Jeyaraja , S Vairamuthu , Md Shafiuzama , P Selvaraj
Published: December 2022

Dilated cardiomyopathy (DCM) is one of the commonly acquired myocardial disease of dogs which most often is accompanied by electrocardiographic abnormalities. The present study was aimed to identify the electrocardiographic (ECG) abnormalities that were present in DCM affected dogs as well as their management. A total of 52 dogs with DCM were evaluated electrocardiographically using RMS Vesta 301i as per standard procedure. Pre-therapeutic electrocardiographic evaluation revealed normal sinus rhythm in 15 cases (28.84%), sinus tachycardia in 18 cases (34.61%), atrial fibrillation in 8 cases (15.38%), ST coving in 6 cases (11.53%), reduced ‘R’ amplitude in 5 cases (9.6%), junctional premature complexes in 2 cases (3.84%), ventricular premature complex in 2 (3.84%), atrial flutter in 1 case (1.92%) and isorhythmic atrioventricular disassociation in 1 case (1.92%). All the cases were treated for DCM using standard protocol. Atrial fibrillation and flutter were treated with Diltiazem @ 1-1.5 mg/kg three times a day and Digoxin @ 0.003 mg/kg twice a day orally and ventricular premature complex was treated with Sotalol @ 1-2 mg/kg two times a day orally. Six cases of atrial fibrillation was presented for follow-up and all achieved effective control of heart rate i.e., rate control and two of them reverted to normal sinus rhythm i.e., rhythm control, one to atrial flutter and three persisted with atrial fibrillation. VPC’s in both the dogs were successfully controlled by 15th day of therapy.
Housing and Feeding Management Practices Followed by Goat Keepers of Middle Gujarat
Authors: Jegoda Mahendra N , Modi Rakesh J
Published: December 2022

A study was conducted in selected areas of Dahod and Kheda districts of Middle Gujarat to ascertain the housing and feeding management practices followed by goat keepers. The data was collected from randomly selected 240 goat keepers (120 each from Dahod and Kheda district) through personal interview with the help of pre-tested structured schedule. The present study revealed that majority of the goat keepers (65.83%) had an enclosed shed for housing their goats followed by open shelter during day or night time by using a deshi clay tiles (61.25%) and thatched type roofed materials (26.67%) and 97.50 % of the goat keepers housed their goats on kutcha floor attached to human dwelling (56.67%) and near to human dwelling (42.50%). Majority of goat keepers (88.75%) used wooden pole in goat shelter and 93.33 % of the goat keepers regularly cleaned goat shelter. Only two fifth of the respondents (40.0%) used feeding trough in goat shelter. Majority of the goat keepers (74.17%) maintained the goats under extensive system followed by semi-stall-feeding system (25.83%) by allowing 4-6 hours of browsing time per day (70.0%) on fallow land or/and forest pasture area by covering about 3-4 km distances daily by flock. About 46.67% goat keepers provided green fodder regularly, while 54.17% respondents fed locally available tree leaves and loppings to the goats regularly and 75.42 % offered dry forages occasionally to goats as per availability of browse, while more than half (57.92 %) of the goat keepers fed home-made concentrates/grains mixture to lactating goats and 64.17 % of the goat keepers provided tube well water for drinking to goats. The district-wise differences were more in providing roofing materials, feeding trough and source of drinking water, and the grazing land was more of plain type in Kheda district.
A Clinical Study on Canine Pyometra
Authors: Verma Atul Kumar , Saroha Harshit , Srivastava Aman , Shambhavi  , Patel Akhil , Tripathi Ashutosh , Shukla Manish Kumar , Singh Vijay
Published: December 2022

Pyometra is an important gynaecological disorder of canine females along with dystocia and transmissible venereal tumor. Canine pyometra is problematic for canine owner and sometimes fatal in canines in severe cases. So, this study was aimed to know the incidence of pyometra among different gynaecological disorders, breed-wise, and factors affecting incidence of pyometra. A total 178 female dogs, presented with gynaecological disorders at VCC, Meerut, were included in this clinical study. Maximum incidence of canine pyometra was observed in five to six years age group. The incidence was found more in nulliparous (intact) animals and in Labrador breed. Incidence of open cervix pyometra was more common than closed cervix pyometra. USG can be used as a tool for the diagnosis of closed cervix pyometra. Mifipristone, Cabergoline, Misoprostol/Dinoprostone (oral/vaginal prostaglandin) along with antibiotic and other supportive therapy was found very effective in canine pyometra.
Comparison of Estradiol Cypionate, Estradiol Benzoate and Gonadotropin-Releasing Hormone in Fixed-Time Artificial Insemination in Multiparous Murrah Buffaloes
Authors: Nain Satish , Kumar Devender , Dholpuria Sandeep , Choudhary Ashok Kumar , Choudhary Archana , Chahar Satish Kumar
Published: December 2022

The present study was aimed to evaluate the efficiency of estradiol cypionate, estradiol benzoate and gonadotropin-releasing hormone during fixed-time artificial insemination (FTAI) protocols in multiparous Murrah buffaloes. A total of 35 buffaloes were used between September and November 2021 and subjected to a synchronization protocol. On day 0, insertion of an intravaginal progesterone device (CIDR, 1.38 g) was made with intramuscular (i/m) injection of estradiol benzoate (EB, 2 mg); On day 9: CIDR removed with i/m injections of Dinoprost (12.5 mg) and eCG (400 IU), and then buffaloes were randomized into three treatment group: 1) EB 1 mg on day 10 (n=13). 2) estradiol cypionate (EC) 1 mg on day 9 (n=12), and 3) Buserelin acetate (GnRH) 0.0105 mg on day 10 (n=10). The estrus signs observed during the FTAI (56 h after CIDR withdrawal) and conception rate at 90 days after FTAI were recorded. The conception rates were 61.5, 58.3 and 60.0% for EB, EC and GnRH treatment groups, respectively. There was no significant difference between the treatment groups for conception rate and signs of estrus. Therefore, it was concluded that all three treatments can be efficiently used during estrus synchronization protocol with FTAI in multiparous Murrah buffaloes.
Isolation and Antibiogram of Escherichia coli from Canine Pyometra in Puducherry Region
Authors: Vignesh Manivasagam , Vasu JayaLakshmi , Nivedha Devanathan , Srinivas Mouttou Vivek , Iyyanar Shalini , Mukhopadhyay Hirak Kumar
Published: December 2022

Pyometra is a life-threatening and hormone induced cystic endometrial hyperplasia seen predominantly in older bitches, complicated with secondary bacterial infections. This study was performed with the objective of isolation and antibiogram of Escherichia coli from canine pyometra. Vaginal swabs were collected aseptically from 20 canine pyometra cases, presented to Veterinary Clinical Complex, Puducherry (India) for identification of E. coli isolates. Based on colony characters, microscopic observation, biochemical tests, 12 (60%)  E. coli isolates were identified. All the 12 phenotypically positive E. coli isolates were confirmed further by PCR using the primer targeting alr gene. E. coli isolates were found sensitive to Gentamicin (100%), Ceftriaxone (83%), Enrofloxacin (75%) and Ciprofloxacin (66%), but were resistant to commonly used antibiotics like Amoxyclav (100%), Ceftazidime (58%) and Cefotaxime (42%). The results provided an authentic and reliable information to choose an effective antibiotic to treat E. coli infection causing canine pyometra.
Mire is jó a nyelvtudás?
Authors: Szilvási-Bódis Zsuzsanna
Published: December 2022

Az egyetemen folyó nyelvoktatás fontosságát és a diploma megszerzéséhez eddig kötelezően előírt nyelvvizsga szükségességét sokan megkérdőjelezik. Ennek több oka is lehet: többek között nem érdekli az idegen nyelv, nem volt sikerélménye a tanulás során, nem tartja a nyelvtudást fontosnak a későbbi élete során, nem tudja megszerezni a nyelvvizsgát. Tanulmányomban azt kívánom megvizsgálni, hogy egyetemünk különböző tudományterületen tanuló hallgatói hogyan vélekednek erről a kérdésről. Azaz mennyire tartják fontosnak az egyetemi idegennyelv-tanulást, van-e céljuk a nyelvvizsga megszerzésén kívül az idegennyelv-tudással, a szakmájukhoz mennyire tartják szükségesnek azt, használják-e tanórán kívül különböző helyzetekben a tanult nyelvet. Emellett a nyelvvizsgával kapcsolatos véleményüket is megismertem. A hallgatók válaszait összességében is áttekintem, ezenfelül külön-külön megvizsgálom a német, illetve angol nyelvet tanulók, valamint a négy tudományterület hallgatóinak véleményét, azért, hogy árnyaltabb képet kapjunk.
Unique Spectrum of Driver Gene Mutations in Patients with Non-Small Cell Lung Carcinoma (NSCLC) from Coal-manufacturing Districts in Southwest China
Authors: Wang Jun-Ling , Yang Chun-Ju , Hu Juan , Liu Hong-Xia , Li Meng-Xian , Fang Zhe-Wei , Yang Jin-Si , Ma Rong , Dai Rui , Xie Qiang , Li Rui , Lv Jia-Ling , Kan Qiang-Bo , Gao Yan-Hong , Yang Ying-Yu , He Kun-Hua , Ci Ce , Zhang Chao , Li Hong-Wei
Published: December 2022

Introduction

The coal-manufacturing districts in the Eastern Yunnan province of Southwest China are the utmost occurrence and death of lung tumors. As previously reported on unique clinical characteristics of non-small cell lung cancer (NSCLC) in patients from these regions without a clear understanding of the aetiology and molecular characteristics. We aim to identify the unique driver gene mutations spectrum.

Material and methods

Samples from 1120 NSCLC patients from Eastern Yunnan were gathered for next-generation sequencing. Seventeen gene targets were sequenced. We have compared individuals' medical and genetic features from the coal- and non-coal-manufacturing zones.

Results

The mutation rates of EGFR (L858R, 19-Del, G719X+L861X, L858R+EGFR amplification) and ERBB2 (20ins) were low in patients from coal-manufacturing regions. Interestingly, EGFR (G719X, S768I, G719X+S768I), KRAS (G12C), TP53 (R158L) and NTRK3 demonstrated a much higher mutation frequency. Furthermore, EGFR compound mutations were linked with the patient's job and TNM staging IIIb-IV. The OncodriverCLUST algorithm authenticated 6 genes (KRAS, EGFR, ROS1, NRAS, BRAF, and ERBB2) as driver genes in patients from coal manufacturing. EGFR with KRAS, BRAF, RET, and TP53 with ALK and KRAS were mutually exclusive. Mutations in the TP53 signaling pathway were the most common in NSCLC patients from the coal-fabricating districts.

Conclusions

Our analyses confirmed the unique spectrum of driver genetic mutations and emphasized the potential of future targeted therapy in NSCLC patients from the coal-manufacturing districts of Eastern Yunnan. Our data broaden the view of NSCLC pathogenesis and its relationship with the environmental conditions in coal-producing regions.
Layout-Generatoren für den Analogentwurf in kleinen Technologieknoten
Authors: Prautsch Hans Dieter Benjamin
Published: December 2022

Der Entwurf analoger integrierter Schaltungen ist in der Ingenieurspraxis eine komplexe und äußerst herausfordernde Aufgabe. Unzählige Details müssen Entwicklungsingenieure bei den erforderlichen Entwurfsschritten berücksichtigen. Durch vielfältige Rückwirkungen und oft unvollständige Spezifikationen sind Iterationen dabei unumgänglich. Gerade bei modernen Technologien mit immer kleineren Strukturbreiten steigen die Rückwirkungen enorm an und so wird die Erfüllung der Spezifikation eine zunehmende Herausforderung in technischer und ökonomischer Hinsicht. Neue Halbleitertechnologien erfordern zudem häufige Aktualisierungen der vom Hersteller per PDK gelieferten Technologiedaten, wodurch es zu

weiteren Entwurfsiterationen kommt. Der noch immer vorwiegend manuelle Analogentwurf wird unter diesen Bedingungen immer aufwendiger und teurer.

Im Rahmen der vorliegenden Arbeit sind daher Methoden entwickelt worden, die es ermöglichen, prozedurale und parametrisierbare Abläufe zur Layouterstellung (und damit prozedurale Generatoren) durch Mittel der Abstraktion auch in kleinen Technologieknoten zu verwenden. Die so realisierte Automatisierung des Layouts beschleunig...
Nephrotic syndrome in a patient with Glycogen Storage Disease Type IXb.
Authors: Yoldas Celik Merve , Yazıcı Havva , Erdem Fehime , Canda Ebru , Sarsik Kumbaraci Banu , Kaplan Bulut Ipek , Kalkan Ucar Sema , Kabasakal Süleyman Caner , Çoker Mahmut
Published: December 2022

Introduction: Glycogen storage disorder (GSD) IXb is characterized by liver and muscle involvement. We present a GSD IXb patient with an incidental union of nephrotic syndrome.

Case Report: A 4 year-old-patient was diagnosed with GSD IXb at 13 months of age with mildly elevated transaminases and hepatomegaly. During the follow-up period, there was no hypoglycemia. Development and growth were normal. In the last month, the onset of generalized edema was reported. Urinalysis showed a high protein level. He had low serum albumin, high serum triglycerides cholesterol. Complement levels were normal. The patient was diagnosed as minimal change disease with a renal biopsy. He was treated with oral prednisone.

Discussion: Minimal Change Disease is the most common cause of idiopathic nephrotic syndrome cases in children and the first step for therapy is the usage of corticosteroids. This is the first report of nephrotic syndrome associated with GSD IXb disease.
ESTEREÓTIPOS DE GÊNERO NA CONTABILIDADE:
Authors: Oliveira Silva Antônia Alícia , Souza Jocykleber Meireles de , Marciano de Freitas Neto Raimundo , De Oliveira Quirino Márcio Cesár
Published: December 2022

O presente estudo tem como objetivo identificar a percepção de estudantes e profissionais contabilistas em relação aos estereótipos relacionados à imagem da mulher contadora. Para tanto, procedeu-se a aplicação de questionário adaptado de Silva, Silva, e Santos (2017), com estudantes e profissionais de contabilidade que residem em Mossoró-RN.  Utilizando-se a estatística descritiva e os testes paramétricos de média (teste t), a fim de identificar as diferenças de percepção entre os dois grupos de respondentes. Os resultados indicam que as profissionais contábeis, foram estereotipadas positivamente como sendo responsáveis, criativas, organizadas, inteligentes, gentis, calmas e proativas. Além disso, por parte dos discentes, foi constatada a concordância de que enfrentam restrições de gênero, que sofrem preconceitos devido à sua condição feminina, além de reconhecer que a dupla jornada influencia seu desempenho. Na percepção dos profissionais, as oportunidades de trabalho são as mesmas para homens e mulheres na área contábil. O estereótipo beleza influencia no crescimento profissional da mulher, e o assédio existe por ser considerada como o “sexo frágil”. Quanto à dupla jornada de trabalho que precisam conciliar, os homens acreditam que essa realidade possa influenciar no seu desempenho profissional, e as mulheres não. Já no ponto sobre a mulher ser mais disciplinada nas atividades rotineiras, os homens discordaram, enquanto as mesmas concordaram. Por fim, não se observou a existência de preconceito quanto à capacidade da mulher na finalização de trabalhos, mas acreditam que estas tendem a ser mais criteriosas ao assumir riscos, além de buscar oportunidades de emprego que proporcione maior estabilidade.
Occurrence of Complex Behaviors in the Uncontrolled Passive Compass Biped Model
Authors: ADDED Essia , GRİTLİ Hassène , BELGHİTH Safya
Published: December 2022

It is widely known that an appropriately built unpowered bipedal robot can walk down an inclined surface with a passive steady gait. The features of such gait are determined by the robot's geometry and inertial properties, as well as the slope angle. The energy needed to keep the biped moving steadily comes from the gravitational potential energy as it descends the inclined surface. The study of such passive natural motions could lead to ideas for managing active walking devices and a better understanding of the human locomotion. The major goal of this study is to further investigate order, chaos and bifurcations and then to demonstrate the complexity of the passive bipedal walk of the compass-gait biped robot by examining different bifurcation diagrams and also by studying the variation of the eigenvalues of the Poincaré map's Jacobian matrix and the variation of the Lyapunov exponents. We reveal also the exhibition of some additional results by changing the inertial and geometrical parameters of the bipedal robot model.
In Silico Approach For Detection Of The Effect Of UGT1A1 Polymorphisms On Telmisartan Response
Authors: KÖPRÜLÜLÜ KÜÇÜK Gizem
Published: December 2022

Hypertension is a cardiovascular disease that manifests itself with a continuous increase in systemic arterial blood pressure and can lead to serious complications over time. It is estimated that 37% of hypertensive patients receive treatment and one-third of them are under control. Telmisartan is an angiotensin receptor blocker used in the treatment of hypertension. Uridine 5'-diphospho-glucuronyltransferase 1 (UGT1A1) gene encodes the Uridine 5'-diphospho-glucuronyltransferase (UGT) enzyme and metabolizes the telmisartan. Single nucleotide polymorphisms cause amino acid, protein structure, and function to change. These changes affect the drug response and therapy. Polymorphisms of the UGT1A1 gene (rs4148323, rs28934877) cause telmisartan resistance. In this study, the SWISS-MODEL database and Chimera 1.15 ver. Programs were used to create homology models. The HOPE database was used to calculate the damage of mutation on protein structure and show the mutation effects on protein. The HDock server was used to demonstrate interactions between telmisartan and wild-type protein and, mutant type protein. It was detected that the mutant residue of UGT1A1 (rs4148323) is located in an important domain for protein activity. Mutation might disturb the protein function. rs28934877 was detected that this mutation is probably damaging to the protein. These mutations cause the loss of interactions and affect the drug response. By docking analysis, Telmisartan drug interactions were shown between wild and mutant types protein Possible drug conformation is designed for the effective treatment of patients carrying the common mutation.
TOPLUMSAL CİNSİYET BAĞLAMINDA KADIN ÂŞIKLAR: ÂŞIK ŞAHSENEM ÖRNEĞİ
Authors: TETİK IŞIK Seher , ARAS İnanç
Published: December 2022

Âşıklık geleneği Türkiye’nin hemen hemen birçok bölgesinde karşımıza çıkmaktadır. Ancak Kars yöresi ve çevresinde geleneğin oldukça yaygın olduğu dikkat çekmektedir. Nitekim geleneğin birçok bölgede giderek kaybolmaya yüz tuttuğu görülse de Kars ve çevresinde canlılığını koruması, yeni çırakların yetiştirilmesi ve Âşıklar Bayramı gibi geleneği destekleyecek özel günlerin düzenlenmesi dolayısıyla bölge, gelenek için önemli hale gelmiştir.
Yörede birçok âşık yetişmiş olsa da bu icracıların genellikle erkek olması, kadın âşıkların yok denecek kadar az olması, bir problem durumu olarak karşımıza çıkmaktadır. Bu nedenle bu araştırmada yöredeki az sayıdaki kadın âşıktan biri olan Âşık Şahsenem örneğinden yola çıkarak yöredeki âşıklık geleneğinin toplumsal cinsiyet perspektifinden değerlendirilmesi amaçlanmıştır. Bu doğrultuda konuya ilişkin belgelerin betimsel tarama yöntemiyle taranmasının yanı sıra Âşık Şahsenem’e ait sesli ve görüntülü kayıtlar incelenmiştir.
Yapılan araştırmalar sonucunda ise âşıklık geleneğinin erkekler tarafından oluşturulduğu, kadın âşıkların özellikle “ana”, “bacı” gibi toplum tarafından kutsal kabul edilen rollerle adlandırılarak âşıklık geleneği içerisindeki varlıklarının meşrulaştırıldığı, Âşık Şahsenem’in kadın âşıklar içerisinde aktif rol oynayan âşıklardan biri olmasına rağmen kendisine yüklenen toplumsal roller nedeniyle birçok sorunla karşılaştığı tespit edilmiştir.
The Effect of Supervision on Employee Performance through Work Discipline on PT. Arvena Agrees on Batang Cenaku District
Authors: Syuaib Nur , Hasan Hazwari , Dandi Lisman , Shaddiq Syahrial , Alhempi R. Rudi
Published: December 2022

This study aims to analyze the effect of insight on the performance of employees through work discipline at PT Arvena Sepakat Indragiri Hulu Regency. The population in this study was 286 employees. Sample retrieval using the purposive sampling method, namely a part of the population was made into a sample of 82 people. Data types and sources are primary data and secunder data, while data collection techniques use observations, questionnaires, and interviews. The data analysis used in this study is structural model analysis, namely t-test, rsquare test and hypothesis test. This study shows that Supervision has a significant positive effect on Employee Performance, Work Discipline has a significant positive effect on Employee Performance, and Supervision has a significant positive effect on Employee Performance through Work Discipline.
Impact Assessment of Indigenous Chickens Production Interventions in the Semi-arid Regions of Zimbabwe: Case of Chivi District
Authors: Tsikai Mudavanhu , Govere Ignatius , Manyeruke Kainos
Published: December 2022

Most communal farmers in Chivi district of Zimbabwe rear indigenous chickens. However, the impact of interventions by government and non-government partners remains unknown. The purpose of this study is to assess impact of indigenous chicken production in semi-arid areas with a focus on Chivi district. The research focused on indigenous chickens as the enterprise has the potential to increase rural population income and in turn improve the nutrition for the rural population. A total of 160 indigenous chicken farmers were sampled from a population of 1240 who received past interventions in trainings, feed and chicks or pullets from development partners and government using a survey questionnaire. Variables such as age, farmer experience, education, type of dwelling, maize, cattle, goats, supplementary feed, type of housing, resting of fowl run, vaccinations and type of hatching method were found to be significantly affecting sales rate. Indigenous chicken production was found to be weakly profitable as a positive gross margin was obtained. The study also revealed that value chain actors in indigenous chicken production had no processors. It was concluded that though indigenous chicken production was profitable, the above stated factors affect impact of indigenous chickens. The value chain map had no processors. Capacitating farmers on poultry management and availing credit to finance production and marketing players is important to improve indigenous chickens among smallholder farmers.
Az egyéni gyermekvállalás és a kisgyermekek napközbeni ellátásának többszintű összefüggései Európában: szakirodalmi áttekintés
Authors: Árki Diána
Published: December 2022

Tanulmányomban bemutatom a hároméves kor alatti gyermekek napközbeni ellátása és az egyéni gyermekvállalás között fennálló kapcsolat elméleti hátterét, és a területi kontextust előtérbe helyező, oksági összefüggést vizsgáló kutatások eredményét hat európai országban. A szociológiai és közgazdaságtani megközelítések, valamint empirikus tapasztalatok alapján ismertetem, hogy a napközbeni ellátás négy paramétere közül elsősorban a szolgáltatás elérhetősége hat a gyermekvállalásra. Rávilágítok arra, miként alakulnak az országspecifikus sajátosságok és a paritás szerinti különbségek a változók között. Azon országokban, ahol alacsony a napközbeni ellátás elérhetősége, főként az anyává válásra gyakorol befolyást a paraméter, míg ahol általánosan elérhető a napközbeni ellátás, csekély hatást fejt ki a mutató, és inkább a második, harmadik gyermek világrajövetelét segíti elő. A kutatások mindemellett felhívták a figyelmet az elérhetőség alsó-felső határértékének fontosságára. Bemutatom továbbá a felmérések azon hiányosságait, melyek orvoslásával megvalósulhat a témakör szélesebb körű és részletesebb európai kutatása.
SISTEM INFORMASI MANAJEMEN STATUS KARYAWAN BERBASIS WEB SECARA ONLINE PADA PT KAYU SENGON INDUSTRI
Authors: Jaka Afid Daya
Published: December 2022

The very rapid development of information technology can meet various human activities and needs, computers are able to provide the effectiveness of a good life for humans, advances in communication tools in the third millennium have made it easier to obtain information from various sources for various interests, especially in various decision-making within companies. That is why it is felt the importance of managing information in an integrated manner in every company organization. This information system provides facilities for entering employee data, printing employee data, evaluating employees and also additional information such as information on employee schedules, registration mechanisms, employee updates, and appointment of position status. Users who will access this application include permanent employees or employees who are still on contract status, web users, and administrators. The design of an employee data management system will be built using SAW, implemented using the PHP (Hypertext preprocessor) programming language and MySql for database management.
PENUAAN POPULASI DAN DAMPAKNYA TERHADAP PERTUMBUHAN EKONOMI MAKRO JANGKA PANJANG DI ASIA TIMUR
Authors: Muhammad Taali  , Triana Prihatinta  , Ardila Prihadyatama
Published: December 2022

This study will examine the impact of the population aging phenomenon on innovation and long-term macroeconomic balance in several East Asian countries. The variables used in this study include the number of elderly population, population growth, income per capita, birth rate, death rate, institutional quality, education level, unemployment rate and gross national expenditure. The data analysis method that will be used is the Monash-China Hunan-University General Equilibrium (MC-HUGE) model which is the development of the Computable General Equilibrium (CGE) model. The MC-HUGE model is built on the Walrasian general equilibrium theory and input-output theory, including the three main elements in production activities, namely land, capital and labor.
ANALISIS PERKEMBANGAN PRODUKSI SARUNG TENUN GOYOR PADA MASA PANDEMI
Authors: Tania Putri Novita Sari  , Anggita Nanda Oktaviani  , Roihatul Janah
Published: December 2022

The fact of industrial development is that in Wanarejan village, Pemalang city is famous for the production of woven fabrics and is a characteristic of the village. so the purpose of this study is to describe the analysis of developments contained in the home industry of weaving in the village of Wanarejan. In this study, the population used were entrepreneurs of goyor woven fabrics. This research is a research with a qualitative approach with descriptive data type, which is trying to present objective facts in accordance with the conditions that occurred at the time the research was conducted. Data collection techniques in this study using observation, interviews and documentation. The results of this study found that the production of woven sarongs is still in demand by people in Pemalang City and in other cities. Sales of this woven sarong export to various countries. Woven fabric products have their own characteristics because of the use of simple weaving techniques with non-machine looms, thus adding a more beautiful, smooth and neat impression. The hallmark of the goyor woven sarong that makes it a fashion with its traditional characteristics lies in its design and good quality level.
REVIEW FAKTOR PENENTU KEPUTUSAN INVESTASI PADA GENERASI Z & MILLENIAL
Authors: Maghfirah Nur Fadilah  , Nathasya Indriwan  , Nur Khoirunnisa  , Sri Mulyantini
Published: December 2022

Investment is one of the trends favored by various generations today, this is evidenced by the percentage growth of assets in 2021. Generation Z & Millennials are the generation that dominates the capital market in Indonesia in 2021. Knowing the behavior and factors that can affect Generation Z & Millennials in making investment decisions is the purpose of this review, so that it can be used by Generation Z & Millennials when making investments in the future. This study uses a literature review method by reviewing the behavior and investment decision factors of Generation Z & Millennials. In developed countries Generation Z & Millennials have understood the impact of investment, while in developing countries Generation Z & Millennials have a high level of trust and choose safer investment instruments. Factors that can influence investment decisions in Generation Z & Millennials include financial literacy, financial attitudes, and financial perceptions.
Model Kebijakan Dividen : Analisis EPS, DER, Dan CR Terhadap Return Saham
Authors: Novya Fitri  , Elfiswandi Elfiswandi  , Ramdani Bayu Putra
Published: December 2022

Issues regarding stock returns are important for the company. Because stock returns are used as a measure of company performance by investors to invest in the stock market. This study aims to determine how the effect of EPS, DER, and CR on stock returns with dividend policy as an intervening variable in property & real estate companies listed on the Indonesia Stock Exchange. The sample in this study was taken by purpove sampling method on property & real estate companies listed on the IDX, namely 12 companies with a research period of 5 years from 2016-2020. The results of this study indicate that EPS, DER, and CR have a significant effect on dividend policy. EPS, DER, CR, and dividend policy have no significant effect on stock returns. Dividend policy is not able to mediate EPS, DER, CR to stock returns in property & real estate companies listed on the Indonesia Stock Exchange with a research period of 5 years from 2016-2020.

Keywords :

Current Ratio; Debt to Equity Ratio; Earning Per Share; Divident Policy; Stock Return.
RANCANG BANGUN TRANSAKSI RENTAL MOBIL DENGAN TEKNOLOGI WEB PADA ALKO RENT CAR
Authors: Rusito Rusito
Published: December 2022

In this modern era, the world of science and technology is growing rapidly. Along with this, the flow of information is also growing and the need for quality information is increasing. CV. ALKO Rent Car is an individual business engaged in services, especially transportation services.The previous rental process only used a borrowing system through advertisements in print media and only by word of mouth. This is of course a bit detrimental to the company, because if there are customers from outside the city who will use the car rental service, they cannot know the types of cars that will be used and the price of the car rental. By using a transaction system with web technology, it ishoped that the company can increase the number of customers and not only from the city of Semarang. In addition, the admin section will not experience difficulties when writing reports or customer data collection, because customer data collection can be done in an easier way by entering the customer member, the admin section will find out whether the customer has used the car rental service or not.With web technologies such as HTML, CSS, PHP and MySQL databases as well as utilizing the internet network, it is hoped that it can solve problems related to customer reach.This study uses the Borg and Gall (1987) model from 10 steps to 6 steps. The expert system validation test shows the final value of the calculation is 2.5, concluding that it is very feasible to use. User Validation on CV. ALKO Rent Car Semarang obtained a value of 3.0 stating that the system is feasible to use and good.
PENINGKATAN RUANG LINGKUP PENJUALAN DAN BRAND KERUPUK ATOM KHAS ANAMBAS
Authors: Edy Yulianto Putra  , Nevi Ariyu De Utami  , Gita Aulia  , Yeffy Yeffy  , Wikandriya Pradinang  , Joy Happy Jones
Published: December 2022

Anambas which has local specialties whose ingredients are made from fresh tuna and then processed into atomic crackers as a typical Anambas souvenir. There is limited distribution so that the product is only known in certain areas without being promoted outside the city. The business development is due to a lack of marketing and the appropriate management has not been applied. This activity aims to help introduce the Atomic Cracker brand so that it is known to the wider community and increase sales. The method of implementing this activity uses qualitative methods. With data collection techniques observation, documentation and interviews. The results of this activity are updating the logo and product packaging, as well as creating Instagram social media accounts. The conclusion of this activity is that the use of marketing using digital media is a new hope for MSMEs Atomic Crackers Typical Anambas to expand marketing by utilizing digital media and directly. The advice that can be given is to pay more attention to social media by regularly uploading content to attract the attention of consumers and looking for more gift shops to maximize sales.
ANALISIS USAHA BUDIDAYA IKAN NILA (Oreochromis niloticus) DALAM KERAMBA JARING APUNG DI PT. RAMA JAYA MAHAKAM DESA LOA KULU KOTA KECAMATAN LOA KULU KABUPATEN KUTAI KARTANEGARA
Authors: Hesty Nurita Putri  , Fitriyana Fitriyana  , Qoriah Saleha
Published: December 2022

The purposes of the study are to determine the income. for freshwater fish farming in floating net cages (KJA) at PT. Rama Jaya Mahakam. This research was conducted from January 2020 to June 2022. The sample determination was based on the Purposive Sampling method, with 1 respondent, namely the business owner, The primary data was obtained from business owners by means of interviews using a list of questions. Data were analyzed by quantitative analysis. The results of the analysis showed that the income was IDR. 212.588.090/year.
PENGELOLAAN PERMINTAAN DAN KAPASITAS PRODUKSI UMKM DI KOTA BATAM (SAHABAT TAICHAN BATAM)
Authors: Shofiy Shofiyah  , Aisyah Fitriana  , Inayah Alifia Fajar  , Tiara Maharani  , James Valentino  , Vera Edelia Lim  , Selvia Zulastri
Published: December 2022

Currently, the development of business in Indonesia is very rapid, especially in the culinary or food sector. This increase phenomenon is based on one of the government's roles in efforts to improve the impact of the COVID-19 pandemic, namely the Micro, Small and Medium Enterprises (MSME) empowerment program. UMKM Sate Sahabat Taichan Batam has the opportunity to develop even better. The purpose of this research is to optimize the production process of UMKM Sate Sahabat Taichan Batam in accordance with the capacity and demand of consumers so that SMEs can predict how much demand for products with separate requests for the future as well as service orders given and the total demand for these products can be known. The data collection method that we use is to conduct interviews so that we can directly get information orally and can get clear data about research problems. The results of the research that the author examines that the pattern of demand from year to year continues to increase for the product. Therefore, with the pattern of product demand that is increasing from consumer demand, the profits obtained by MSME owners are also increasing and the development of branch outlets helps overcome consumer demand.