bluuebunny/crossref_metadata_2025 huggingface dataset:
An improved solution method via the pole-transformation process for the maximum-crossrange problem
Authors: Zhou Xiang , Zhang Hong-Bo , Xie Lei , Tang Guo-Jian , Bao Wei-Min
Published: March 2020

The maximum-crossrange problem is difficult to solve rapidly and stably because of highly nonlinear dynamics and nonconvex constraints. In this paper, an improved successive second-cone programming method via the pole-transformation process is proposed. The main contribution of this work is twofold. Firstly, the pole-transformation coordinate frame is defined, and the original problem is reformulated by the pole-transformation process to avoid the linearization of downrange and crossrange angles. The terminal state constraint is relaxed to an inequality constraint, which improves the stability performance of the solution method. Secondly, an adaptively adjustment method of the trust-region contraction coefficient is proposed to improve the convergence performance of the solution method. The optimal solution of the original problem is obtained by the improved successive second-order cone programming method. The numerical experiments verify the effectiveness of the pole-transformation process, and the convergence and stability performances of the improved solution method proposed in this paper.
High pre-exposure prophylaxis awareness and willingness to pay for pre-exposure prophylaxis among young adults in Western Kenya: results from a population-based survey
Authors: Begnel Emily R , Escudero Jaclyn , Mugambi Melissa , Mugwanya Kenneth , Kinuthia John , Beima-Sofie Kristin , Dettinger Julia C , Baeten Jared M , John-Stewart Grace , Pintye Jillian
Published: March 2020

We conducted a population-level short message service (SMS)-based survey among individuals aged 18–34 years in six HIV high-burden counties in Western Kenya to assess pre-exposure prophylaxis (PrEP) awareness, acceptability of non-facility PrEP delivery, and willingness to pay for PrEP. In January 2019, anonymous data were collected using mSurvey Inc., Nairobi, Kenya, which sends SMS messages via mobile provider networks to a ‘general audience’ pool of subscribers ≥18 years. Subscribers’ demographic information was matched to Kenyan census data by age, gender, and county. Of the 3825 individuals who received the survey, 2617 (68%) opened the survey and 2498/2617 (95%) completed all questions. Overall, 84% had ever heard of PrEP, of whom 59% demonstrated understanding of PrEP; understanding was greater among men than women (64% versus 55%, p < 0.001). Among participants who understood PrEP (n = 1249), 38% reported pharmacies (informal or formal) as the preferred venue to obtain PrEP. Over half (61%) were willing to pay for PrEP and 78% reported that the maximum amount they were willing to pay for a one-month supply was <5 USD. High awareness of PrEP in high HIV prevalence settings in Kenya suggests effective public health messaging. Willingness to pay and preference for pharmacy access suggest that non-facility PrEP delivery may be useful.
Neuroprotective role of luteolin against lead acetate-induced cortical damage in rats
Authors: Baty RS , Hassan KE , Alsharif KF , El-Hennamy RE , Elmahallawy EK , Hafez MM , Moneim AE Abdel , Kassab RB
Published: March 2020

Luteolin (LUT) is a glycosylated flavonoid compound that has multiple beneficial pharmacological and biological impacts. The current investigation was undertaken to evaluate the putative neuroprotective potency of LUT against neuronal damage induced by lead acetate (PbAc). Twenty-eight rats were placed into four equal groups. Group 1: served as the control group, group 2: rats were supplemented orally with LUT (50 mg kg−1), group 3: rats were intraperitoneally injected with PbAc (20 mg kg−1), and group 4: rats were pretreated with LUT before PbAc injection with the same doses. All animals were treated for 7 days. The exposure to PbAc increased the concentration of lead in the cortical tissue, neuronal lipid peroxidation, and nitric oxide (NO) production and decreased the antioxidant enzymes. Additionally, PbAc enhanced a neuroinflammatory response in the cortical tissue through increasing the pro-inflammatory cytokines secretion and inducible NO synthase expression. Moreover, cortical cell death was recorded following PbAc intoxication as evidenced by the enhancement of the proapoptotic and inhibiting the antiapoptotic markers. Interestingly, LUT supplementation reversed the cortical adverse reactions induced by PbAc. Taken together, these findings may suggest that LUT may be useful for attenuating neuronal damage induced by PbAc through inhibiting the oxidative damage, neuroinflammation, and the cortical cell death.
Introduction to special issue on digitalization, labour and global production
Authors: Raj-Reichert Gale , Zajak Sabrina , Helmerich Nicole
Published: March 2020

This special issue contributes to the emerging literature on digitalization and its impact on work and workers in global systems of production. Three key themes are featured in the collection of papers. They are on the relationship between the use of digital communication technologies and power relationships, working conditions of online workers or crowd-workers, and shifting geographies of production. The papers also largely focus on the global South, contributing to research on digitalization and labour which has thus far tended to examine large and higher income countries mainly in the global North. This introductory article expands on and situates the papers broadly within the literature on digitalization and labour and within the three themes more specifically, and discusses their implications for future research.
“Those People Count”: Naloxone Media Coverage in Mississippi
Authors: Bagley Braden , Bright Candace Forbes
Published: March 2020

There is a movement to promote naloxone adoption by law enforcement and other stakeholders in the state of Mississippi. The purpose of this study is to understand how local media are framing the conversation about naloxone products, and to better understand how it might affect naloxone adoption among law enforcement. We searched for news articles published in Mississippi from January 2012 to July 2018 mentioning the words Narcan® and/or naloxone. Four main themes emerged from 25 articles: (a) positive and informative discussion of naloxone, (b) full articles persuading readers to use and/or advocate the use of naloxone, (c) government or organizational effort to increase the availability and use of naloxone products, and (d) negative or misleading information about naloxone. Better efforts to disseminate correct and persuasive information about the drug will have a profound and positive effect on the opioid epidemic in Mississippi and in the United States.
Parental Exposure to Childhood Maltreatment and Offspring’s Mental Health: Investigating Pathways Through Parental Adversity and Offspring Exposure to Maltreatment
Authors: Negriff Sonya , Palmer Molina Abigail , Hackman Daniel A.
Published: March 2020

Parental exposure to child maltreatment (CM) is an important predictor of their offspring’s CM experiences and mental health. However, less attention has been paid to examine possible mechanisms of transmission, which is critical to inform prevention and intervention efforts. The current study tested (1) whether the association between parental CM exposure and offspring CM exposure was mediated by (a) parental exposure to violence in adulthood or (b) other emotional stressors/adversities in adulthood and (2) the indirect effects from parental CM exposure to offspring mental health outcomes through parental adversity and offspring CM exposure. Data came from a longitudinal study of maltreatment on adolescent development, and analyses focused on adolescents living with a biological parent ( N = 185, 51% female). Biological parents (95% mothers) reported on their history of CM and exposure to other adversities across their lifetime. Adolescents self-reported lifetime CM experiences and current depression, anxiety, posttraumatic stress disorder, and externalizing behaviors in late adolescence ( Mage= 18.49). Results showed a significant indirect effect of parent CM exposure on offspring’s CM exposure and mental health through parental emotional stressors/adversities, but not physical violence. These findings highlight different types of stressors that may impact the risk for intergenerational transmission of CM and subsequent offspring mental health.
Party crashers? Modeling genuinely new party development paths in Western Europe
Authors: Emanuele Vincenzo , Sikk Allan
Published: March 2020

Western Europe has recently experienced the emergence of successful new parties, but while single parties or countries have been extensively studied, insufficient attention has been devoted to this phenomenon from a comparative and long-term perspective. By relying on an original data set covering 20 countries and 344 parliamentary elections, this article presents the first analysis of West European ‘genuinely new parties’ (GNPs) across time, countries and party families. We hypothesize that the parties differ not only in terms of their short- and long-term success but have a range of distinct development paths. Through a latent growth model, we provide a classification of GNPs in terms of their breakthrough and initial performance. According to the specific trajectory followed by new parties in the first five elections they contest, the model suggests five different classes of new parties in Western Europe: ‘explosive’, ‘meteoric’, ‘contender’, ‘flat’ and ‘flop’. The article discusses the implications of these findings also regarding the ability of the model to produce estimates and predictions about the future electoral performances of GNPs.
Can realism save us from populism? Rousseau in the digital age
Authors: Cozzaglio Ilaria
Published: March 2020

In 2016, the Five Stars Movement (5SM), one of the parties currently in power in Italy, launched the ‘Rousseau platform’. This is a platform meant to enhance direct democracy, transparency and the real participation of the people in the making of laws, policies and political proposals. Although ennobled with the name of Rousseau, the 5SM’s redemptive promise has been strongly criticised in the public sphere for being irresponsible and ideological. Political realism, I will argue, can perform both a diagnostic and a corrective task, by providing some tools to unveil populist distortions and by offering more solid grounds for political opponents’ critique. Three aspects of realism, in particular, will be pointed out as remedies against populist drifts. First, anti-moralism, complemented by anti-utopianism and contextualism, criticises the populists’ moralistic picture of politics, its anti-pluralistic attitude and its rejection of the role of experts in politics. Second, the Weberian ethic of responsibility offers standards to assess politicians’ actions, instead of embracing the populist aversion towards any professional politician; besides, it contrasts the populist image of politics as a derogatory activity. Finally, realism as ideology critique unveils the distorting narratives underlying populist propaganda and fostering uncritical support.
Digital Stories as Data: An Etymological and Philosophical Exploration of Cocreated Data in Philosophical Hermeneutic Health Research
Authors: Lang Michael , Laing Catherine , Ewashen Carol , Moules Nancy
Published: March 2020

Many research methods emphasize procedures to minimize potential bias introduced by measurement tools, environmental factors, and researchers themselves. Using the example of digital storytelling, in which short films are cocreated between a researcher and participant, we examine the possibility of cocreated stories as data in philosophical hermeneutic (PH) health research. The etymological explication of the words “data” and “story” brings the meaning of these words closer together while an exploration of the ontological and epistemological assumptions of PH indicate that cocreated digital stories can be viewed as data in a similar way to traditional verbatim interview transcripts used in other types of qualitative health research. Using digital storytelling as a data generation tool in PH health research may help provide a deeper understanding of health-related phenomena by cultivating understanding through genuine conversation, addressing the challenges of language, and apprehending the immediacy of understanding.
Epi: An open humanoid platform for developmental robotics
Authors: Johansson Birger , Tjøstheim Trond A , Balkenius Christian
Published: March 2020

Epi is a humanoid robot developed by Lund University Cognitive Science Robotics Group. It was designed to be used in experiments in developmental robotics and has proportions to give a childlike impression while still being decidedly robotic. The robot head has two degrees of freedom in the neck and each eye can independently move laterally. There is a camera in each eye to make stereovision possible. The arms are designed to resemble those of a human. Each arm has five degrees of freedom, three in the shoulder, one in the elbow and one in the wrist. The hands have four movable fingers and a stationary thumb. A force distribution mechanism inside the hand connect a single servo to the movable fingers and makes sure the hand closes around an object regardless of its shape. The rigid parts of the hands are 3D printed in PLA and HIPS while the flexible parts, including the joints and the tendons, are made from polyurethane rubber. The control system for Epi is based on neurophysiological data and is implemented using the Ikaros system. Most of the sensory and motor processing is done at 40 Hz to allow smooth movements. The irises of the eyes can change colour and the pupils can dilate and contract. There is also a grid of LEDs that resembles a mouth that can be animated by changing colour and intensity.
Enhanced participation or just another activity? The social shaping of iPad use for youths with intellectual disabilities
Authors: Isaksson Charlotta , Björquist Elisabet
Published: March 2020

The use of smartphones and tablet devices in activities is believed to have great potential for enhancing the participation of people with intellectual disabilities. However, these technologies, in themselves, do not contribute to participation. What matters is how they are used. Employing the concept of domestication and insights gained from interviews with staff, this article examines conditions for the enhanced participation of youths with intellectual disability and how tablet devices are being integrated into social care settings, in particular.

The findings reveal two approaches to tablet integration. In one approach, tablet use is an organized practice focused on technology acquisition, skills improvement and entertainment. In the other, it is integrated into existing practices as an aid to interpersonal communication. The organized digital activities create conditions for the youths to participate like non-disabled peers. The greatest potential for enabling participation with each other is when the youths themselves initiate the use of tablets.
Training monitoring methods used in the field by coaches and practitioners: A systematic review
Authors: McGuigan Hannah , Hassmén Peter , Rosic Nedeljka , Stevens Christopher J
Published: March 2020

Athletes’ optimal training progression can be supported by reliable and valid monitoring tools. This systematic review aims to investigate tools that have been most frequently in the field used by coaches and practitioners of sports of any level. PyscINFO, Scopus, MEDLINE and SPORTDiscus databases were searched. Search terms used include: overreaching, overtraining, recover, fatigue, overload, train; monitor, athlete monitor, train monitor and coach, sport scientist, or performance coach. From the 1982 search results retrieved, seven articles met the inclusion criteria. The inclusion criteria required articles to be descriptive or observational studies on the training monitoring of athletes, be peer-reviewed, and in English. Physiological measures (e.g. heart rate) and measures of performance and workload (e.g. tests including sprints; global positioning system variables) were most frequently used. Psychological self-reported questionnaires, such as ratings of perceived exertion and mood inventories, were also frequently used in the field. The results indicated that only a few biochemical measures (blood and urine analysis) were regularly used outside of a laboratory. Easily implemented measurements were more commonly used than more advanced ones, indicating that the tools valued by practitioners are those that are time efficient, easy to administer and are non-fatiguing and non-invasive. Knowing what tools are currently used in the field is the first step in knowing what is practical and usable for coaches in the field, where after coaches and practitioners collaborating with sport scientists can develop and implement tools that are both useable and easily administered.
Anti-N-methyl-d-aspartate receptor encephalitis: A primer for acute care healthcare professionals
Authors: Anderson Dustin , Nathoo Nabeela , McCombe Jennifer A , Smyth Penelope , Brindley Peter G
Published: March 2020

This primer summarizes the diagnosis, treatment, complications, and prognosis of anti-N-methyl-d-aspartate receptor encephalitis for healthcare professionals, especially those in acute care specialities. Anti-N-methyl-d-aspartate receptor encephalitis is an immune-mediated encephalitis that is classically paraneoplastic and associated with ovarian teratomas in young women. Other less common neoplastic triggers include testicular cancers, Hodgkin lymphoma, lung and breast cancers. It may also be triggered by infection, occurring as a para-infectious phenomenon, seen most commonly after herpes simplex-1 encephalitis. Presentation varies but typically consists of behavioural and cognitive manifestations, seizures, dysautonomia, movement disorders, central hypoventilation, and coma, necessitating intensive care unit admission. Diagnosis of anti-N-methyl-d-aspartate receptor encephalitis requires high clinical suspicion plus ancillary testing, the most sensitive being cerebrospinal fluid analysis for anti-N-methyl-d-aspartate receptor antibodies. Imaging in search of an ovarian teratoma should be exhaustive and tumours need to be surgically treated. Treatment should be expeditious with pulsed steroids and either plasma exchange or intravenous immunoglobulin. Second-line treatments include intravenous rituximab, cyclophosphamide, azathioprine, and intrathecal methotrexate. Most patients recover to be functionally independent, but the in-hospital course can be months long followed by extensive rehabilitation. Given the lengthy course of illness, we explain why education and debriefing are important for staff, and where families can obtain additional help.
What is the incidence of complex regional pain syndrome (CRPS) Type I within four months of a wrist fracture in the adult population? A systematic review
Authors: Rolls Catherine , McCabe Candy , Llewellyn Alison , Jones Gareth T
Published: March 2020

Introduction

Complex regional pain syndrome (CRPS) is a severe chronic pain condition, the symptoms of which may develop following trauma to a limb. Despite wrist fracture being a common antecedent, estimates of the incidence of CRPS following this injury vary widely. Our objective was to establish the incidence of CRPS in adults within four months of a wrist fracture, using a systematic review of the literature published since 2010.

Methods

The databases MEDLINE, PubMed, EMBASE, PsychINFO, CINAHL, BNI and AMED were searched for observational studies reporting the incidence of CRPS following a wrist fracture. Inclusion criteria were the use of a validated diagnostic tool to assess for CRPS within four months of the fracture. Randomised controlled trials and clinical trials were excluded, as were data from patients with evidence of prior neurology. Incidence risk was then extracted or calculated. Included studies were assessed for methodological rigour using the Newcastle–Ottowa Scale for assessment of bias.

Results

Nine studies met the inclusion criteria. There was a high degree of heterogeneity in study populations including study setting, fracture management and diagnostic criteria. From the three studies with the highest methodological rigour we determined that the incidence risk of CRPS in adults is between 3.7% and 14% using the Budapest criteria, with an observation of lower rates in conservatively managed fractures.

Discussion

We found evidence that the reported incidence of CRPS is influenced by choice of diagnostic criteria, along with the study location and/or how the fracture is managed.
An Association Between Hyperchloremia and Acute Kidney Injury in Patients With Acute Ischemic Stroke
Authors: Haller J. Tyler , Smetana Keaton , Erdman Michael J. , Miano Todd A. , Riha Heidi M. , Rinaldi Alyssa , Goyal Nitin , Jones G. Morgan
Published: March 2020

Background and Purpose:

While an association between hyperchloremia and worse outcomes, such as acute kidney injury and increased mortality, has been demonstrated in hemorrhagic stroke, it is unclear whether the same relationship exists after acute ischemic stroke. This study aims to determine the relationship between moderate hyperchloremia (serum chloride ≥115 mmol/L) and acute kidney injury in patients with ischemic stroke.

Methods:

This is a multicenter, retrospective, propensity-matched cohort study of adults admitted for acute ischemic stroke. The primary objective was to determine the relationship between moderate hyperchloremia and acute kidney injury, as defined by the Acute Kidney Injury Network criteria. Secondary objectives included mortality and hospital length of stay.

Results:

A total of 407 patients were included in the unmatched cohort (332 nonhyperchloremia and 75 hyperchloremia) and 114 patients (57 in each group) were matched based upon propensity scores. In the matched cohort, hyperchloremia was associated with an increased risk of acute kidney injury (relative risk 1.91 [95% confidence interval 1.01-3.59]) and a longer hospital length of stay (16 vs 12 days; P = .03). Mortality was higher in the hyperchloremia group (19.3% vs 10.5%, P = .19), but this did not reach statistical significance.

Conclusions:

In this study, hyperchloremia after ischemic stroke was associated with increased rates of acute kidney injury and longer hospital length of stay. Further research is needed to determine which interventions may increase chloride levels in patients with acute ischemic stroke and the association between hyperchloremia and clinical outcomes.
Symptom Control of Patients With Chronic Rhinosinusitis With Nasal Polyps Under Maintenance Therapy With Daily Acetylsalicylic Acid
Authors: Hahn Janina , Appel Heike , Scheithauer Marc O. , Petereit Florian , Greve Jens , Lindemann Jörg , Hoffmann Thomas K. , Veit Johannes A. , Sommer Fabian
Published: March 2020

Introduction

Nonsteroidal anti-inflammatory drugs (NSAID)-exacerbated respiratory disease (NERD) is defined by intolerance to cyclooxygenase 1 inhibitors, chronic rhinosinusitis with recurrent nasal polyps, and/or intrinsic bronchial asthma. Long-term administration of acetylsalicylic acid (ASA) after desensitization has been used to mitigate these sequelae, but the optimal dose and balancing symptom relief and side effects remain unsettled.

Methods

Retrospective data analysis of 85 patients with NERD receiving maintenance therapy of 300 mg ASA was followed by questionnaires (our own, not validated and the Sino-Nasal Outcome Test-20). We received responses from 55 patients and examined 30 of them clinically.

Results

Patients with no ASA-associated side effects were 56.4% (56 of 85 patients) of the cohort. In this study, 60% (33 of 55 patients) continued prophylaxis of 300 mg ASA daily for an average of 34.7 months. Elective surgery was the most frequent cause of discontinuation of ASA (21.8%; 12 of 55 patients). Rhinomanometry values were significantly improved with ASA ( P < .05; Wilcoxon), but there was no significant reduction in nasal polyposis or improvement in olfaction at the time of follow-up examination.

Conclusions

Minor clinical improvements were identified. Side effects were well tolerated by most patients, and no serious sequelae occurred. The indications for long-term ASA therapy in NERD patients remain unsettled.
Dynamic Corridor Illusion in Pigeons: Humanlike Pictorial Cue Precedence Over Motion Parallax Cue in Size Perception
Authors: Hataji Yuya , Kuroshima Hika , Fujita Kazuo
Published: March 2020

Depth information is necessary for perceiving the real size of objects at varying visual distances. To investigate to what extent this size constancy present in another vertebrate class, we addressed the two questions using pigeons: (a) whether pigeons see a corridor illusion based on size constancy and (b) whether pigeons prioritize pictorial cues over motion parallax cues for size constancy, like humans. We trained pigeons to classify target sizes on a corridor. In addition, we presented a dynamic version of corridor illusion in which the target and corridor moved side by side. Target speed was changed to manipulate motion parallax. With the static corridor, pigeons overestimated the target size when it was located higher, indicating that pigeons see a corridor illusion like humans. With the dynamic corridor, the pigeons overestimated the target size depending on target position, as in the static condition, but target speed did not affect their responses, indicating that the pictorial precedence also applies to pigeons. In a follow-up experiment using the same stimulus, we confirmed that humans perceive object size based on pictorial cues. These results suggest that size constancy characteristics are highly similar between pigeons and humans, despite the differences in their phylogeny and neural systems.
Left ventricular hypertrophy in athletes: How to differentiate between hypertensive heart disease and athlete’s heart
Authors: D’Ascenzi Flavio , Fiorentini Caterina , Anselmi Francesca , Mondillo Sergio
Published: March 2020

Athlete’s heart is typically accompanied by a remodelling of the cardiac chambers induced by exercise. However, although competitive athletes are commonly considered healthy, they can be affected by cardiac disorders characterised by an increase in left ventricular mass and wall thickness, such as hypertension. Unfortunately, training-induced increase in left ventricular mass, wall thickness, and atrial and ventricular dilatation observed in competitive athletes may mimic the pathological remodelling of pathological hypertrophy. As a consequence, distinguishing between athlete’s heart and hypertension can sometimes be challenging. The present review aimed to focus on the differential diagnosis between hypertensive heart disease and athlete’s heart, providing clinical information useful to distinguish between physiological and pathological remodelling.
A systematic review of the behaviour change techniques and digital features in technology-driven type 2 diabetes prevention interventions
Authors: Van Rhoon Luke , Byrne Molly , Morrissey Eimear , Murphy Jane , McSharry Jenny
Published: March 2020

Objectives

Our aim was to conduct a systematic review to determine which technology-driven diabetes prevention interventions were effective in producing clinically significant weight loss, and to identify the behaviour change techniques and digital features frequently used in effective interventions.

Methods

We searched five databases (CINAHL, EMBASE, MEDLINE, PsychINFO, and Pubmed) from inception to September 2018 and reviewed 19 experimental and non-experimental studies of 21 technology-driven diet plus physical activity interventions for adults (≥18 years) at risk of developing type 2 diabetes. Behaviour change techniques were coded using the BCT taxonomy v1, and digital features were identified via thematic analysis of intervention descriptions.

Results

Sixty-three per cent of interventions were effective in the short term (achieving ≥3% weight loss at ≤6 months), using an average of 5.6 more behaviour change techniques than non-effective interventions, and 33% were effective in the long term (achieving ≥5% weight loss at ≥12 months), using 3.7 more behaviour change techniques than non-effective interventions. The techniques of social support (unspecified), goal setting (outcome/behaviour), feedback on behaviour, and self-monitoring of outcome(s) of behaviour were identified in over 90% of effective interventions. Interventions containing digital features that facilitated health and lifestyle education, behaviour/outcome tracking, and/or online health coaching were most effective.

Conclusion

The integration of specific behaviour change techniques and digital features may optimise digital diabetes prevention interventions to achieve clinically significant weight loss. Additional research is needed to identify the mechanisms in which behaviour change techniques and digital features directly influence physical activity, dietary behaviours, and intervention engagement.
Catering for Learner Diversity in Hong Kong Secondary Schools: Insights from the Relationships Between Students’ Learning Styles and Approaches
Authors: Yin Hongbiao , Lee John Chi-Kin , Zhang Zhonghua
Published: March 2020

Purpose:

Catering for learner diversity is a key issue in the recent educational reforms in Hong Kong. The present study addresses this issue through an investigation of the relationships between students’ learning styles and approaches to learning in Hong Kong secondary schools.

Design/Approach/Methods:

A total of 6,054 junior secondary students in Hong Kong responded to a questionnaire consisting of two instruments. A series of confirmatory factor analysis, two-way analysis of variance, and structural equation modeling analysis were conducted.

Findings:

The results identified three types of learning style among the students which are characterized by a cognitive orientation, a social orientation, and a methodological orientation. Some significant gender- and achievement-level differences were revealed. Compared with the socially oriented learning style, the cognitively and methodologically oriented learning styles were more extensively and strongly related to students’ approaches to learning, even though these students showed a greater preference for the socially oriented learning style.

Originality/Value:

It is unwise to blindly cater for students’ learning styles in classroom teaching and curriculum design. Teachers should adopt a comprehensive and balanced approach toward the design of curriculum and teaching which not only highlights the congruence between students’ learning styles and teacher’s pedagogy but also integrates the constructive frictions between them into classroom teaching.
Workplace Smoking Cessation in Costa Rica: Pilot Study Findings
Authors: Feldman Robert H. , Villalobos-Pérez Alfonso , Rodríguez Roberto G.
Published: March 2020

Background: In Costa Rica, the leading cause of preventable death is smoking. Adults spend one third of their lives at work making the workplace an optimal site for smoking cessation interventions. Therefore, we developed a workplace smoking cessation pilot program among Costa Rican Justice Department government employees based on key Costa Rican values and best practices. Methods: First, focus groups were conducted among exsmokers and smokers. Participants in the focus groups and in the subsequent smoking cessation pilot study were invited to take part in the study through flyers, information sheets, and announcements from the Justice Department. The focus groups revealed that social factors were fundamental to quitting. Therefore, based on these results two programs (14 participants) were conducted consisting of seven sessions encouraging employees to utilize their family and exsmokers. Data were collected before and after the seven sessions on smoking behavior, social influence, and other factors. Findings: Five of 14 (36%) quit smoking. None of the quitters lived with a smoker, as compared with 56% of nonquitters who lived with a smoker. Also, quitters were less likely to have friends (40% vs. 67%) and coworkers (20% vs. 33%) who smoked compared with nonquitters. Conclusion/Application to Practice: Workplace smoking cessation programs should help smokers to increase their social contacts with nonsmokers/exsmokers. Smoking cessation programs should assess not only smoking patterns, but also social contacts, such as family, friends, and coworkers. Based on these assessments, smokers should be encouraged to seek-out nonsmokers/exsmokers to assist them in quitting.
Helicopter Parenting Is Unrelated to Student Success and Well-Being: A Latent Profile Analysis of Perceived Parenting and Academic Motivation During the Transition to University
Authors: Howard Andrea L. , Alexander Sean M. , Dunn Leigh C.
Published: March 2020

We examined helicopter parenting (e.g., intervening, assisting with tasks that emerging adults are capable of performing independently) during the transition to university relative to positive parenting (autonomy support, warmth, age-appropriate involvement) and academic motivation. Participants were n = 460 full-time, first-year undergraduates who completed surveys in September and December. In a latent profile analysis, differences were prominent for positive parenting (three profiles featured relatively low, moderate, and high levels). Amotivation was highest in combination with lower positive parenting. Intrinsic motivation was highest in combination with higher positive parenting; helicopter parenting was similar across profiles and was not meaningfully associated with end-of-semester well-being. End-of-semester outcomes were poorest for low positive parenting, but supplemental analyses showed disadvantages were already evident in September. Perceptions of parents during the transition to university likely reflect continuity from adolescent parenting environments. Results do not support the narrative that helicopter parenting is common or a barrier to student success.
Massive Fatal Pulmonary Embolism While on Therapeutic Heparin Drip
Authors: Hajouli Said
Published: March 2020

Venous thromboembolism (VTE) includes deep venous thrombosis (DVT) and pulmonary embolism (PE). In this article, we present a case of a patient with an acute DVT who was treated with a therapeutic heparin drip, then developed syncope while in the hospital and found to have massive bilateral PEs. This case aims to arouse the medical staff’s awareness of the VTE diagnosis even if the patient is fully anticoagulated. We review the indications for DVT hospitalization, heparin infusion monitoring, risk factors for developing PE from DVT, mechanisms of developing PE from DVT while on therapeutic anticoagulation, and signs and treatment of massive PE.
Age and Tightness of Repair Are Predictors of Heel-Rise Height After Achilles Tendon Rupture
Authors: Carmont Michael R. , Zellers Jennifer A. , Brorsson Annelie , Nilsson-Helander Katarina , Karlsson Jón , Grävare Silbernagel Karin
Published: March 2020

Background:

Achilles tendon rupture leads to weakness of ankle plantarflexion. Treatment of Achilles tendon rupture should aim to restore function while minimizing weakness and complications of management.

Purpose:

To determine the influence of factors (age, sex, body mass index [BMI], weight, time from injury to operative repair, and tightness of repair) in the initial surgical management of patients after an acute Achilles tendon rupture on 12-month functional outcome assessment after percutaneous and minimally invasive repair.

Study Design:

Cohort study; Level of evidence, 3.

Methods:

From May 2012 to January 2018, patients sustaining an Achilles tendon rupture receiving operative repair were prospectively evaluated. Tightness of repair was quantified using the intraoperative Achilles tendon resting angle (ATRA). Heel-rise height index (HRHI) was used as the primary 12-month outcome variable. Secondary outcome measures included Achilles tendon total rupture score (ATRS) and Tegner score. Stepwise multiple regression was used to create a model to predict 12-month HRHI.

Results:

A total of 122 patients met the inclusion criteria for data analysis (mean ± SD age, 44.1 ± 10.8 years; 78% male; mean ± SD BMI, 28.1 ± 4.3 kg/m2). The elapsed time to surgery was 6.5 ± 4.0 days. At 12-month follow-up, patients had an HRHI of 82% ± 16% and performed 82% ± 17% of repetitions compared with the noninjured side. Participants had a mean ATRS of 87 ± 15 and a median Tegner score of 5 (range, 1-9), with a reduction in Tegner score of 2 from preinjury levels. The relative ATRA at 12 months was –4.8° ± 3.9°. Multiple regression identified younger age (B = ±0.006; P < .001) and greater intraoperative ATRA (B = 0.005; P = .053) as predictors of more symmetrical 12-month HRHI ( R 2 = 0.19; P < .001; n = 120).

Conclusion:

Age was found to be the strongest predictor of outcome after Achilles tendon rupture. The most important modifiable risk factor was the tightness of repair. It is recommended that repair be performed as tight as possible to optimize heel-rise height 1 year after Achilles tendon rupture and possibly to reduce tendon elongation.
Correlation Between Bone Density and Lumbar Compression Fractures
Authors: Takahashi Toshihide , Takada Tomoya , Narushima Takeshi , Tsukada Atsuro , Ishikawa Eiichi , Matsumura Akira
Published: March 2020

Objectives: Bone densitometry is widely used to evaluate osteoporosis; however, it is pointed out that bone density may be high in the case of fractures, deformities, and osteosclerotic changes. The present study evaluated bone density measured at our hospital and evaluated its correlation with the presence or absence of lumbar spine fractures. Methods: Bone density of the lumbar spine and femur was measured in 185 patients from July 2017 to June 2019 at our hospital, and the presence or absence of a lumbar spine compression fracture was evaluated on the basis of the image. Information regarding age, sex, lumbar bone density, presence or absence of lumbar fracture, number of lumbar fractures, and grade of lumbar fracture was also statistically evaluated. Results: Analysis was performed for 185 patients (20 males and 165 females, average age 76.9 ± 7.5 years). The bone density was 0.830 ± 0.229 of compression fractured bodies (number of vertebral bodies were 132) and 0.765 ± 0.178 g/cm3 of noncompression fractured bodies (number of vertebral bodies was 608). Discussion: The presence of lumbar fractures significantly increases bone density. For diagnosing osteoporosis, both bone density and the possibility of lumbar spine fractures must be considered.
Expressive language abilities of boys with idiopathic autism spectrum disorder and boys with fragile X syndrome + autism spectrum disorder: Cross-context comparisons
Authors: Hilvert Elizabeth , Sterling Audra , Haebig Eileen , Friedman Laura
Published: March 2020

Background and aims

Understanding the unique expressive language profiles of children with phenotypically similar, but distinct neurodevelopmental disorders, such as idiopathic autism spectrum disorder and fragile X syndrome with a co-diagnosis of autism spectrum disorder (fragile X syndrome + autism spectrum disorder), has both clinical and theoretical implications. However, comparative studies of these two clinical groups have been limited, and results have been inconsistent, partially as a result of different assessment methods being utilized. Thus, the current study compared the expressive language profiles of boys with idiopathic autism spectrum disorder and boys with fragile X syndrome + autism spectrum disorder and examined whether a similar linguistic profile emerged across different language sampling contexts: a semi-structured conversation and the Autism Diagnostic Observation Schedule.

Methods

Eighteen boys with autism spectrum disorder ( Mage = 13.25 years) and 19 boys with fragile X syndrome + autism spectrum disorder ( Mage = 12.19 years), matched on autism spectrum disorder symptom severity and similar in terms of chronological age and mean length of utterance, participated in this study. Boys produced two language samples: one semi-structured conversation and one taken from the Autism Diagnostic Observation Schedule. Language samples were coded for talkativeness, lexical diversity, mean length of utterance, intelligibility, and repetitive or perseverative language.

Results

Analyses revealed that boys with autism spectrum disorder produced language samples that were more lexically diverse and intelligible, and that included less topic perseveration compared to boys with fragile X syndrome + autism spectrum disorder. With regards to sampling context, boys in both groups were more talkative and produced longer and more intelligible utterances in their conversation sample compared to their Autism Diagnostic Observation Schedule sample. However, boys with autism spectrum disorder and fragile X syndrome + autism spectrum disorder used a higher proportion of topic perseveration during the conversation sample.

Conclusions

Overall, we found similarities as well as distinctions in the expressive language profiles of boys with fragile X syndrome + autism spectrum disorder and boys with idiopathic autism spectrum disorder. Moreover, the Autism Diagnostic Observation Schedule sample elicited a relatively different language profile than the conversation sample for boys in both groups.

Implications

These findings help to further elucidate the unique language phenotypes of boys with idiopathic autism spectrum disorder and boys with fragile X syndrome + autism spectrum disorder. Moreover, our findings indicate that multiple language samples may be needed to obtain a comprehensive account of a child’s expressive language ability.
Framework for School Stage Entrepreneurship Education in Nigeria
Authors: Agboola Olayode W.
Published: March 2020

This article investigates the influence of entrepreneurship education at the school stage, over and above personal, social, and institutional factors, on entrepreneurship with a view to providing a framework for school stage entrepreneurship education in Nigeria. Findings based on cross tabulations as well as hierarchical regression analyses using data from the Global Entrepreneurship Monitor indicate that entrepreneurship education at school stage makes significant contribution to the variation in entrepreneurship over and above personal, social, and institutional factors in Nigeria, as opposed to formal education and entrepreneurial education at postschool stage. Furthermore, personal and institutional factors are found to contribute incrementally to entrepreneurial intention, while personal and social factors contribute incrementally to entrepreneurial activity in Nigeria. The study recommends and provides a framework for the formal integration of entrepreneurship education into teaching curricula at the school stage to promote latent entrepreneurship and thereby serve as a pedestal for entrepreneurship education at postschool stage in Nigeria.
SUGAMMADEX versus neostigmine after ROCURONIUM continuous infusion in patients undergoing liver transplantation
Authors: Deana Cristian , Barbariol Federico , D’Incà Stefano , Pompei Livia , Rocca Giorgio Della
Published: March 2020

Background

Rapid neuromuscular block reversal at the end of major abdominal surgery is recommended to avoid any postoperative residual block. To date, no study has evaluated sugammadex performance after rocuronium administration in patients undergoing liver transplantation.

This is a randomized controlled trial with the primary objective of assessing the neuromuscular transmission recovery time obtained with sugammadex versus neostigmine after rocuronium induced neuromuscular blockade in patients undergoing orthotopic liver transplantation.

Methods

The TOF-Watch SX®, calibrated and linked to a portable computer equipped with TOF-Watch SX Monitor Software®, was used to monitor and record intraoperative neuromuscular block maintained with a continuous infusion of rocuronium. Anaesthetic management was standardized as per our institution’s internal protocol. At the end of surgery, neuromuscular moderate block reversal was obtained by administration of 2 mg/kg of sugammadex or 50 mcg/kg of neostigmine (plus 10 mcg/kg of atropine).

Results

Data from 41 patients undergoing liver transplantation were analysed. In this population, recovery from neuromuscular block was faster following sugammadex administration than neostigmine administration, with mean times±SD of 9.4 ± 4.6 min and 34.6 ± 24.9 min, respectively (p < 0.0001).

Conclusion

Sugammadex is able to reverse neuromuscular block maintained by rocuronium continuous infusion in patients undergoing liver transplantation. The mean reversal time obtained with sugammadex was significantly faster than that for neostigmine. It is important to note that the sugammadex recovery time in this population was found to be considerably longer than in other surgical settings, and should be considered in clinical practice.

Trial registration

ClinicalTrials.govNCT02697929 (registered 3rd March 2016).
The omitted symptoms challenge the diagnosis of right atrial myxoma: a case report
Authors: Ma Shulun , Xu Qian , Shi Ruizheng , Zhang Xin , Chen Xuliang
Published: March 2020

Background

Cardiac myxoma (CM) is the most common type of primary cardiac tumors. The prevalence of primary cardiac tumors is 0.0017–0.28% in various autopsy studies. The clinical symptoms of CM which includes embolism, intracardiac obstruction, general or constitutional manifestations and infected myxoma are largely depended on the size, growing speed, location and pedicle length of the tumor. The following case reported a missed diagnostic case of a right atrial myxoma firstly presented digestive, systemic symptoms and immunologic disorder, leading to emergent tricuspid valves obstruction situation.

Case presentation

We reported a critical case of a 51-year-old female with CM was firstly admitted to the gastroenterology clinical department because of poor appetite, marked fatigability and weight loss for 2 months. The physician diagnosed her as chronic gastritis and treated her with some symptomatic treatment such as ilaprazole and magnesium aluminum carbonate. After months without definitive diagnosis, this right atrial myxoma grew into right ventricle and obstructed the tricuspid valves, causing her dyspnea, sweating, dizziness, feeling of impending death when she was sleeping. Transthoracic echocardiogram revealed a 6.1 × 4.2 × 3.7 cm2 mass adjacent to tricuspid valves. The patient underwent surgical excision and pathology revealed a primary cardiac myxoma.

Conclusion

This case reported a critical result of missed diagnosis of right atrial myxoma and showed its systematic symptoms and immunologic disorder, highlighting the importance of systematic examinations on patients. Furthermore, it appeals early diagnosis of CM and consideration of drug targets to suppress CM development.