bluuebunny/crossref_metadata_2025 huggingface dataset:
Sociodemographic Determinants and Students’ Perception Regarding Legislative Changes
Authors: Parvu Simona ,   Hygiene and Medical Ecology Department, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania,   Simona Parvu, MD Dr. Anastasievici Leonte Street, 1-3 050463, Bucharest, Romania E-mail: simona.parvu@insp.gov.ro Phone: 0040724943392
Published: November 2022

The frequency of legislation changes and their utility is a subject of interest and always under debate with pro and contra arguments. In the current study, the perception of students regarding medical legislation changes was analyzed. In general, no statistically significant differences were found between the sub-groups of students, thus underlining a unitary perception. The general perception is that changes in legislation are made too often. Moreover, only a small part of the analyzed group agrees on the utility of these changes. Finally, it seems that income is the main driver for students as future employees in the medical system. Also, significant differences between males and females’ perceptions are emphasized, and legislation changes should take into account the primary drivers. Other issues, such as corruption, stability, and performances should be the key points in legislation changes. These results should be a challenge for all stakeholders, in particular for policymakers.
Making Things Easier: A Simple Novel Method to Fix a Dorsiflexion Osteotomy of the First Metatarsal
Authors: Kurar Langhit ,   Department of Orthopedics, Guy’s and St Thomas’ NHS Foundation Trust, London, United Kingdom,   Langhit Kurar, Specialist Registrar Trauma and Orthopaedic Surgery, 120 Woodside Road, Amersham, Buckinghamshire, HP6 6NP. Phone: 07866596096. E-mail: langhitkurar@nhs.net, Nash William ,   Department of Orthopedics, Guy’s and St Thomas’ NHS Foundation Trust, London, United Kingdom, Faroug Radwane ,   Department of Orthopedics, Guy’s and St Thomas’ NHS Foundation Trust, London, United Kingdom, Hussain Laila ,   Department of Orthopedics, Guy’s and St Thomas’ NHS Foundation Trust, London, United Kingdom, Walker Roland ,   Department of Orthopedics, Guy’s and St Thomas’ NHS Foundation Trust, London, United Kingdom, Abbasian Ali ,   Department of Orthopedics, Guy’s and St Thomas’ NHS Foundation Trust, London, United Kingdom, Latif Ahmed ,   Department of Orthopedics, Guy’s and St Thomas’ NHS Foundation Trust, London, United Kingdom, Singh Samrendu ,   Department of Orthopedics, Guy’s and St Thomas’ NHS Foundation Trust, London, United Kingdom
Published: November 2022

A first ray dorsiflexion osteotomy is commonly performed for cavovarus foot correction. There are multiple techniques to fix this osteotomy, ranging from wires, screws, and plates or a combination of these. We present our results using a varisation staple (Biomet©) as an alternative fixation device. We performed a retrospective outcome analysis of a consecutive series of 10 cavovarus feet that underwent a dorsiflexion osteotomy (dorsal closing wedge) of the first metatarsal fixed with two varisation staples. The results were measured at a mean three monthly follow-ups and included union and complication rates, as well as clinical and radiographic assessment of cavus deformity correction. There was a 100% union rate with no complications or cases of delayed union. No metalwork removal was requested in any case at follow-up. First ray dorsiflexion osteotomies are most commonly fixed using a 3.5mm cortical screw. We demonstrate that our alternative and novel technique using varisation staples achieved a 100% union rate while avoiding the prominent hardware complications known to occur with cortical screws or plates.
A Comparative Study of Connective Tissue Metabolism Indices in Experimental Comorbidity-Free Periodontitis and Periodontitis Combined with Thyroid Dysfunction
Authors: Shcherba Vitaliy ,   Department of Dentistry, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine;, Kyryliv Mariia ,   Department of General Chemistry, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine;, Bekus Iryna ,   Department of General Chemistry, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine;, Krynytska Inna ,   Department of Functional and Laboratory Diagnostics, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine;, Marushchak Mariya ,   Department of Functional and Laboratory Diagnostics, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine;,   Mariya Marushchak, Professor, Department of Functional and Laboratory Diagnostics, Horbachevsky Ternopil National Medical University, Ternopil, Ukraine E-mail: marushchak@tdmu.edu.ua, Korda Mykhaylo ,   Department of Medical Biochemistry, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine
Published: November 2022

Periodontal disease is a chronic bacterial infection characterized by persistent inflammation, connective tissue breakdown, and alveolar bone destruction. The current study aimed to compare the connective tissue metabolism indices in rats with comorbidity-free periodontitis and in animals with periodontitis in a setting of hyper-and hypothyroidism. 12-14-week-old inbred white male rats (n=48) were included in the experiment. They were randomly divided into the following groups: control, animals with a model of periodontitis, animals with periodontitis in a setting of hyperthyroidism, animals with periodontitis in a setting of hypothyroidism. Serum levels of free thyroxine, free triiodothyronine, and thyroid-stimulating hormone were assayed using ELISA kits manufactured by Vector Best (Russia) to confirm the hyper- and hypothyroid status. Collagenolytic activity, the content of glycosaminoglycans, free hydroxyproline, and fucose, unbound with proteins in blood serum were assayed using the spectrophotometric method. We have found the increasing of collagenolytic activity by 46.1% (р<0.001), the content of free hydroxyproline by 74.1% (р<0.001), the content of glycosaminoglycans by 1.8 times (р<0.001), the content of fucose, unbound with proteins by 2.8 times (р<0.001) in rats with periodontitis vs. the control group. The development of periodontitis in a setting of thyroid dysfunction leads to an even more significant increase in the destruction of connective tissue, which is confirmed by a significant increase in the content of studied indices vs. euthyroid animals, both in hyperthyroidism and hypothyroidism.
Social and Psychiatric Aspects of the Emigration Problem in Ukraine
Authors: Petrivna Venger Olena ,   Department of Psychiatry, Narcology and Medical Psychology, I. Horbachevsky Ternopil State Medical University, Ternopil, Ukraine,   Olena Petrivna Venger, MD, PhD Ternopil Regional Clinical Psychoneurological Hospital 14, Trolleybusna Str.,46027, Ternopil, Ukraine Phone/Fax: +38 (0352) 43-57-71 Mobile: +38 (067) 756-55-56 E-mail: olenavenger@gmail.com, Ihorovych Mysula Yuriy ,   Department of Psychiatry, Narcology and Medical Psychology, I. Horbachevsky Ternopil State Medical University, Ternopil, Ukraine, Serhiivna Mysula Marianna ,   Department of Psychiatry, Narcology and Medical Psychology, I. Horbachevsky Ternopil State Medical University, Ternopil, Ukraine
Published: November 2022

The article presents data on a new scheme of complex treatment and rehabilitation of emigrants with psychogenic, endogenous and organic depressive disorders, as well as the results of comparative analysis of the effectiveness of this scheme, compared to the traditional one.

The use of the proposed treatment scheme also allowed to reduce the severity of anxiety, indicators of the severity of psychopathological symptoms, improve the quality of life among emigrants suffering from depressive disorders of different genesis.

The received results allow us to recommend the scheme we have developed for implementation in the complex treatment of emigrants suffering from depressive disorders of psychogenic, endogenous, and organic genesis.
Glucocorticoids and Trabecular Bone Score
Authors: Sandru Florica ,   Department of Dermatology, Elias Emergency University Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Carsote Mara ,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania,   Department of Endocrinology, C.I.Parhon National Institute of Endocrinology, Bucharest, Romania,   Mara Carsote C.I.Parhon National Institute of Endocrinology,Aviatorilor Ave 34-38,Bucharest, Romania.E-mail: carsote_m@hotmail.com, Cristian Dumitrascu Mihai ,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania,   Department of Gynecology, Emergency University Hospital, Bucharest, Romania, Elena Albu Simona ,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania,   Department of Gynecology, Emergency University Hospital, Bucharest, Romania, Valea Ana ,   Department of Endocrinology, Clinical County Hospital, Cluj-Napoca, Romania,   “Iuliu Hatieganu” University of Medicine and Pharmacy, Cluj-Napoca, Romania
Published: November 2022

TBS (Trabecular Bone Score) is the latest tool for clinicians to evaluate bone micro-architecture based on a pixel greyscale, which is provided by lumbar dual-energy X-ray absorptiometry (DXA). Its use enhances fracture prediction in addition to DXA-BMD (Bone Mineral Density). This is independent of fracture risk assessment (FRAX) and DXA results. We present a narrative review regarding the connection between TBS and Glucocorticoids (GC), either as a drug used for different conditions or as a tumor-produced endogenous excess.

TBS is a better discriminator for GC-induced vertebral fractures compared to DXA-BMD. This aspect is similarly available for patients with osteoporosis diagnosed by DXA. TBS is inversely correlated with the cumulative dose of GC (systemic or inhaled), with disease duration, and positively correlated with respiratory function in patients with asthma. Low TBS values are found in females with a T-score at the hip within the osteoporosis range, with diabetes mellitus, or who use GC. Lumbar TBS is a screening tool in menopausal women with type 2 diabetes mellitus. TBS is an independent parameter that provides information regarding skeleton deterioration in diabetic patients receiving GC therapy in a manner complementary to DXA-BMD. TBS might become an essential step regarding the adrenalectomy decision in patients with adrenal incidentaloma in whom autonomous cortisol secretion might damage bone micro-architecture. TBS currently represents a standard tool of fracture risk evaluation in patients receiving GC therapy or with endogenous Cushing’s syndrome, a tool easy to be applied by different practitioners since GCs are largely used
The Patients’ Beliefs Regarding the Role of Food, Mucosal Trauma, Menstruation, and Psychological Stress in the Recurrence of Behçet’s Disease Symptoms
Authors: Shenavandeh Saeedeh ,   Department of Internal Medicine, Division of Rheumatology, Shiraz University of Medical Sciences, Shiraz, Iran, Asis Marziye ,   Department of Internal Medicine, Division of Rheumatology, Shiraz University of Medical Sciences, Shiraz, Iran,   Marziye Asis, MD, Department of Internal Medicine, Division of Rheumatology, Shiraz University of Medical Sciences, Namazee Hospital, Shiraz, Iran, PO Box: 71345-1414, Phone/fax: +98-711-6474316, E-mail: dr.masisi@gmail.com, Hassan Eftekhari Mohammad ,   Department of Clinical Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran, Aflaki Elham ,   Department of Internal Medicine, Division of Rheumatology, Shiraz University of Medical Sciences, Shiraz, Iran, Reza Abdollahifard Gholam ,   Department of Community Medicine, Shiraz University of Medical Sciences, Shiraz, Iran, Anvar Abnavi Marjan ,   Department of Psychiatry, Shiraz University of Medical Sciences, Shiraz, Iran, Ahmadi Afsaneh ,   Research Center for Health Sciences, Department of Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran
Published: November 2022

Behçet’s disease is a systemic vasculitis. Mucocutaneous involvement is the most prominent finding, but triggering factors are not well-known. We decided to assess the beliefs of patients with Behçet’s disease regarding the potential role of food, mucosal injury, menstruation, and stress in the appearance of symptoms. In this cross-sectional study, 60 patients with Behçet’s disease who fulfilled the International Study Group criteria for Behçet’s disease and referred to the outpatient Behçet’s clinic of Motahari, affiliated to Shiraz University of Medical Sciences, were included. A questionnaire was designed by the research team consisting of the rheumatologist involved in the study, two dietitians, and a psychiatrist. The patients were interviewed face-to-face to fill in the questionnaire. The assessed variables were all food categories, menstruation, psychological stress, and oral mucosal injury as the potential triggers of symptoms onset. The most common foods reported as triggers for oral ulcers were eggplant (78.3%), melon (68.3%), walnut (68.2%), and cantaloupe (66.7%). Walnut was reported by three patients (5%) as the most common trigger for genital ulcers. Nervous tension (83%) and annoying arguments (45%) were the two most common psychological stress triggers for oral ulcers. Seven patients (11.7%) reported tooth brushing, as the trigger for oral ulcers. The irregular menstrual cycle was a trigger for oral ulcers in only two patients. Food items such as eggplant, walnut and melon were common self-reported triggers for mucocutaneous lesions in patients with Behçet’s disease. Nervous tension and annoying arguments were also common psychological triggers for oral aphthous ulcers.
The Clinico-Epidemiological Profile of Patients with Gonorrhoea and Challenges in the Management of Neisseria gonorrhoeae Infection in an STI clinic, Ternopil, Ukraine (2013-2018)
Authors: Boiko Iryna ,   Department of Functional and Laboratory Diagnostics, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine,   Iryna Boiko, M.D., PhD student Department of Functional and Laboratory Diagnostics I.Horbachevsky Ternopil National Medical University, 46000, Maidan Voli, 1, Ternopil, Ukraine. Phone: +380676821787 E-mail: iryna.boiko.ua@gmail.com, Akimova Viorika ,   Department of Clinical Laboratory Diagnostic, Danylo Halytsky Lviv National Medical University, Lviv, Ukraine, Mazur Lyudmyla ,   Department of Clinical Immunology, Allergology and General Patients’ Care, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine;, Savchenko Iryna ,   First Department of Internal Medicine, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine;, Kohut Ihor ,   Department of Infectious Diseases with Epidemiology, Skin and Sexually Transmitted Diseases, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine., Krynytska Inna ,   Department of Functional and Laboratory Diagnostics, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine
Published: November 2022

Gonorrhea is the second most common sexually transmitted infection spreading worldwide and a serious public health problem. How�ever, further data are required to improve the management of gonorrhea.

Our aim was to review the features of gonococcal infection and characterize the challenges of its management.

A retrospective descriptive study of the medical records of 136 adult patients with gonorrhea that visited Ternopil Regional Sexually Transmitted Infections Clinic (Ukraine) in 2013-2018 was performed.

The male-to-female ratio was 6.6:1. Homosexually-acquired gonorrhoea was 3.7%. Also, most patients acquired gonorrhea in Ukraine (98.4%). The mean infectious period lasted 2-16 days, including the incubation period of 1-9 days and the period from the onset of symptoms to the first visit of the clinic of 1-7 days. The probability of N. gonorrhoeae transmission within the frame of the epidemiologic sexual chain was 1:2.4. Concurrent T. vaginalis (39.7%) and C. trachomatis (2.2%) were detected. HIV and syphilis screening rates were 1.6% and 0.7%, respectively. The examining rate of sexual partners was 11%, testing extragenital specimens - 0.7%, screening coverage for HIV - 46.3%, compliance with follow-up visits - 41.9%. Part of patients (16.2%) received monotherapy with clarithromycin, doxycycline, benzylpenicillin, azithromycin, or ofloxacin.

The management of N. gonorrhoeae infections was compromised by a low rate of examining sexual partners, females and testing extragenital specimens, screening for HIV, compliance to follow-up visits, access to nucleic acid amplification tests, and receiving questionable or even obsolete antimicrobial treatment. Therefore, more accurate and comprehensive management of gonorrhea is urgently needed in Ukraine.
Current Trends on Glomerulosclerosis Regression
Authors: Stoian Marilena ,   Clinic of Internal Medicine, Dr.I.Cantacuzino Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine, Bucharest, Romania,   Marilena Stoian MD, PhD, 65 Matei Basarab Street, District 3, Bucharest, Romania. E-mail: marilenastoian@yahoo.com, Stoica Victor ,   Clinic of Internal Medicine, Dr.I.Cantacuzino Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine, Bucharest, Romania
Published: November 2022

The role of the renin-angiotensin system in hypertension and end-organ damage has long been recognized. Angiotensin l converting enzyme inhibitors are superior to other antihypertensive agents in protecting the kidney against progressive deterioration, even in normotensive persons. Likewise, angiotensin II type 1 receptor antagonists improve or even reverse glomerulosclerosis in rat animal models. These findings suggest that Angiotensin II has nonhemodynamic effects in progressive renal disease. The renin-angiotensin system is now recognized to be linked to the induction of plasminogen activator-inhibitor-1, possibly via the AT4 receptor, thus promoting both thrombosis and fibrosis. Interactions of the renin-angiotensin system with aldosterone and bradykinin may impact both blood pressure and tissue injury. The beneficial effect on renal fibrosis of inhibiting the renin-angiotensin system likely reflects the central role that angiotensin has in regulating renal function and structure by its various actions. This article explores the renin-angiotensin-aldosterone system with plasminogen activator-inhibitor-1 interaction and the potential significance of these interactions in the pathogenesis of progressive renal disease and remodeling of renal sclerosis.
The Correlations of Clinical and Biochemical Indices of Vitamin D with Erectile Dysfunction
Authors: Dumbraveanu Ion ,   Department of Urology and Surgical Nephrology, Nicolae Testemiceanu State Medical and Pharmaceutical University, Chisinau, The Republic of Moldova, Banov Pavel ,   Department of Urology and Surgical Nephrology, Nicolae Testemiceanu State Medical and Pharmaceutical University, Chisinau, The Republic of Moldova,   Pavel Banov, Associate Professor, Department of Urology and Surgical Nephrology, Nicolae Testemiceanu State Medical and Pharmaceutical University, Chisinau, The Republic of Moldova, 29 Nicolae Testemitanu Street, Chisinau MD 2025, Chisinau 2004. Phone: +(373) 69080331. E-mail: pavel.banov@usmf.md, Arian Iurie ,   Department of Urology and Surgical Nephrology, Nicolae Testemiceanu State Medical and Pharmaceutical University, Chisinau, The Republic of Moldova, Ceban Emil ,   Department of Urology and Surgical Nephrology, Nicolae Testemiceanu State Medical and Pharmaceutical University, Chisinau, The Republic of Moldova
Published: November 2022

Erectile dysfunction is a multifactorial disease; it has been demonstrated that endothelial dysfunction plays an essential role in the pathogenesis of this disease, and Vitamin D deficiency is considered to favor endothelial lesions.

Our study, based on a group of 58 patients who have erectile dysfunction and a control group of 26 healthy subjects, tends to confirm that low levels of vitamin D could potentiate the severity of erectile dysfunction, promoting endothelial dysfunction.

Statistical analysis using the Pearson’s correlation criteria showed a robust and significant correlation between vitamin D levels and erectile dysfunction severity (ρ=0.752, p<0.000) according to the SHIM (Sexual Health Inventory For Men) questionnaire. Also, in patients with erectile dysfunction, there is a strong association between vitamin D and testosterone levels (ρ=0.728, p<0.000). At the same time, a negative correlation between vitamin D and BMI (ρ=-0.517, p<0.000); cholesterol (ρ=-0.560, p<0.001), and triglycerides(ρ=-0.529, p<0.005) was observed. Also, a moderate correlation between erectile dysfunction severity degree and testosterone levels (ρ=0.544) was also detected, and the same severity parameter of erectile dysfunction correlates negatively with cholesterol levels (ρ=-0.534). In its turn, the testosterone level correlates negatively with other biochemical indices: cholesterol (ρ=-0.694) and triglycerides (ρ=-0.670).

Vitamin D level reduction, concomitantly with decreased testosterone and increased cholesterol, contributes to the development and maintenance of erectile dysfunction, more probably through endothelial mechanisms. The assessment of vitamin D values can be used as an independent marker in erectile dysfunction assessment. Thus, one of the diagnostic tests recommended for erectile dysfunction should be the determination of the vitamin D serum level.
Investigation of the Effect of Formaldehyde on the Condition of Periodontal Tissues of Woodworking Industry Workers
Authors: Мykhaylivna Tokar Olha ,   Department of Therapeutic Dentistry, Bukovinian State Medical University, Chernivtsi, Ukraine, Мarkianovich Batig Victor ,   Department of Therapeutic Dentistry, Bukovinian State Medical University, Chernivtsi, Ukraine, Оleksandrivna Ostafiichuk Marianna ,   Department of Therapeutic Dentistry, Bukovinian State Medical University, Chernivtsi, Ukraine, Оlegovich Ishkov Mykola ,   Department of Therapeutic Dentistry, Bukovinian State Medical University, Chernivtsi, Ukraine, Ivanovich Sheremet Michael ,   Surgery Department No.1, Bukovinian State Medical University, Chernivtsi, Ukraine,   Michael Ivanovici Sheremet, Surgery Department No.1, Bukovinian State Medical University, 191 Holovna street, 58018 Chernovtsy, Ukraine. E-mail: mihayl71@gmail.com. Phone: +380956064607
Published: November 2022

The high prevalence of periodontal diseases in workers with professional contact with unfavorable factors of the production environment is an unresolved problem of dentistry. This study aimed to investigate the harmful effects of formaldehyde on periodontal tissues in woodworkers who have long-term contact with formaldehyde in their professional activities. Sixty-nine men with occupational exposure to formaldehyde were examined to study the effect of formaldehyde on the human periodontal tissues, looking particularly at signs of the periodontal tissues’ inflammatory process using a series of periodontal indices. The study results showed that the condition of periodontal tissues was statistically significantly worse in woodworkers who have long-term contact with formaldehyde in their professional activities. However, the hygiene status was not significantly different in the main group and the comparison group. Thus, we concluded that working under conditions of constant exposure to formaldehyde has a negative effect on the condition of periodontal tissues.
Evaluation of Dental Health in Terminally Ill Patients
Authors: Kumari Minti ,   Department of Public Health Dentistry, Patna Dental College and Hospital, Patna, India, Kumar Tanoj ,   Department of Oral Pathology and Microbiology, Patna Dental College and Hospital, Patna, India,   Dr. Tanoj Kumar, Professor and Head,Department of Oral Pathology and Microbiology,Patna Dental College and Hospital, Patna, Bihar E-mail: drtanojkumar@rediffmail.com Phone: +919431647732, Rai Shweta ,   Department of Oral and Maxillofacial Surgery, Buddha Institute of Dental Sciences and Hospital, Kankarbagh, Patna, India, Rai Anurag ,   Department of Orthodontics, Patna Dental College and Hospital, Bankipore, Patna, India, Sultana Rafat ,   Lifeline Dental Care, Gaya, Patna, India, Priya Leena ,   Department of Oral Medicine And Radiology, Buddha Institute of Dental Science and Hospital, Patna, India
Published: November 2022

Dental health plays an imperative role in the general health and well-being of an individual. Terminally ill patients due to a compromised immune response are susceptible to a wide array of oral complications, which may affect their ability to speak and chew, leading to malnutrition.

The present study was conducted to evaluate dental health and various oral manifestations in terminally ill patients.

One hundred twenty terminally ill patients hospitalized with diseases of the respiratory tract, gastrointestinal tract, circulatory system, liver, and endocrinal disorders were included in the study. The evaluation of oral manifestations and their prevalence was done by a single examiner. The oral health was evaluated according to symptoms exhibited by the patients and clinical presentation.

Of the patients included in the study, 78 were male, and 42 were female. All the individuals were adults between 25 to 55 years of age. Out of 120 admitted terminally ill patients, 27 subjects had respiratory diseases, 17 had gastrointestinal disorders, 5 had disorders of the circulatory system, 39 had liver disorders, and 32 had endocrine disorders.

A need for added comprehension is mandatory to link the inter-relationships between dentistry and medicine to further perk up the management of the overall health of patients, which will further reinforce the partnership between dental and medical communities.
Comparison of the Laryngoscopic View using Macintosh and Miller Blades in Children Less than Four Years Old
Authors: Soltani Alireza Ebrahim ,   Anaesthesiology Department, Children’s Hospital Medical Centre, Tehran University of Medical Sciences, Tehran, Iran, Maleki Anahid ,   Anaesthesiology Department, Children’s Hospital Medical Centre, Tehran University of Medical Sciences, Tehran, Iran, Espahbodi Ebrahim ,   Anaesthesiology Department, Children’s Hospital Medical Centre, Tehran University of Medical Sciences, Tehran, Iran, Goudarzi Mehrdad ,   Anaesthesiology Department, Children’s Hospital Medical Centre, Tehran University of Medical Sciences, Tehran, Iran, Ariana Parastou ,   Anaesthesiology Department, Children’s Hospital Medical Centre, Tehran University of Medical Sciences, Tehran, Iran, Takzare Alireza ,   Anaesthesiology Department, Children’s Hospital Medical Centre, Tehran University of Medical Sciences, Tehran, Iran,   Alireza Takzare Anaesthesiology Department, Children’s Hospital Medical Centre,Tehran University of Medical Sciences, Tehran, Iran E-mail: ar-takzare@tums.ac.ir
Published: November 2022

This study aimed to compare Miller and Macintosh laryngoscopes in zero to 4-year-old children. A total of 72 children with a score of I and II, according to the American Society of Anesthesiologists (ASA) physical status classification, who were candidates for elective surgery with general anesthesia and tracheal intubation were enrolled in the study. The children were divided into two equal groups (36 persons) according to used laryngoscope: Miller laryngoscope (group 1) and Macintosh laryngoscope (group 2). Observations and all laryngoscopies were performed by a single experienced anesthesiologist. Heart rate, systolic blood pressure, non-invasive arterial blood pressure, and hemoglobin saturation were measured and recorded. The number of endotracheal intubation attempts and complications were also recorded for both groups. In terms of gender, the first group consisted of 88.9% boys and 11.1% girls, and the second group consisted of 66.6% boys and 33.3% girls (p-value=0.05). The mean age was 16.7 months in the first group and 17.7 months in the second group (p-value=0.5). The mean weight of the children was 16988.5 g and 16300 g in the Miller and Macintosh groups, respectively (p-value=0.9). Regarding the Cormack-Lehane classification system, 5 patients were classified as grade 1 (13.9%), 14 patients as grade 2 (38.9%), 15 patients as grade 3 (41.7%), and 2 patients as grade 4 (5.6%) in the Macintosh group. In contrast, in the Miller group, 5 patients were classified as grade 1 (13.9%), 27 patients as grade 2 (75%), and 4 patients as grade 3 (11.1%) (p-value=0.004). These results can provide more data about the tracheal intubation method with the Macintosh and Miller laryngoscopes, the ease of intubation, and the best laryngoscopic view with each blade.
Role of Risk Assessment in Prevention of Work-Related Accidents and Diseases in Hospital Staff
Authors: Boariu Dan Ioan ,   Occupational Safety and Health Department, Bucharest Emergency University Hospital, Bucharest, Romania,   Boariu Dan-Ioan, PhD Student Bucharest University Emergency Hospital,169 Splaiul Independenţei 169, District 5, Phone: +400788664017, E-mail: danioanboariu@yahoo.com, Armean Petru ,   “Carol Davila” University of Medicine and Pharmacy Bucharest, Bucharest, Romania
Published: November 2022

Risk assessment is an essential component of the occupational health and safety event prevention activity.The purpose of this study is to choose the most appropriate risk assessment method for hospitals. The main methods were compared. There are many assessment methods, each with its advantages and disadvantages, but none has been adapted to the specificities of hospital activity. We adapted the workplace assessment sheet from the INCDPM (National Research and Development Institute for Labor Protection Bucharest) method to the specific of the hospital units and used this method at the level of jobs, within the hospital’s departments, calculating the global risk level per job position, workplace (department), and hospital. The clinical departments global risk level exceeds the average (3.00) for all jobs, but does not exceed, however, 3.50, representing an acceptable security level. For assess the psychosocial risks we used the ELVIE method. Looking ahead, the methods should be adapted to allow both numerical presentation of the results and graphic.
Pentacam Indices in Photorefractive Keratectomy Surgery
Authors: Maraghechi Ghazal ,   School of Medicine, Ardabil Azad University, Ardabil, Iran, Ojaghi Habib ,   Department of Surgery, School of Medicine and Allied Medical Sciences, Imam Reza Hospital,Ardabil University of Medical Sciences, Ardabil, Iran,   Habib Ojaghi, Department of Surgery, School of Medicine and Allied Medical Sciences, Imam Reza Hospital, Ardabil University of Medical Sciences, Ardabil, Iran.Phone: +989141525109 E-mail: habibojaghi@yahoo.com, Amani Firouz ,   School of Medicine and Allied Medical Sciences, Ardabil University of Medical Sciences, Ardabil, Iran, Zahirian Moghadam Telma ,   Social Determinants of Health Research Center, Ardabil University of Medical Sciences, Ardabil, Iran
Published: November 2022

Refractive eye surgeries are one of the most non-emergent ophthalmic surgeries due to the effect on the reduction of refractive errors, increasing visual acuity, enhancing the quality of vision, and indirectly increasing the quality of life of patients. The aim of this study was to determine Pentacam indices in the patients who underwent photorefractive keratectomy (PRK) during 2014-2018, as well as to show their correlation with the type of refractive error. This descriptive cross-sectional study was performed on 2215 eyes of 1125 patients undergoing PRK surgery. The patients’ checklist, including demographic information, refractive index, keratometry, pachymetry, corneal surface zone indices, and progressive corneal thickness indices, was provided. All data were analyzed using the IBM SPSS software, version 25. The findings showed that there was a significant association between posterior corneal astigmatism (PCA) and anterior corneal astigmatism (ACA) (p=0.00). The mean Kmax front was recorded as 44.844 ± 1.58 D, which was significantly correlated with the type of refractive errors (p=0.00). According to the findings, there was a significant relationship between anterior chamber indices and refractive error types and their severity (p=0.00). There was also a significant correlation between the surface zone and keratoconus indices (i.e., index of surface variance - ISV, index of vertical asymmetry - IVA, index of height asymmetry - IHA, and minimum radius of curvature - Rmin) with refractive errors (p=0.00). The findings showed that some of the Pentacam indices could be related to the types of refractive errors in patients undergoing PRK surgery. Therefore, their evaluation is of great importance in this regard.
Multiparametric Ultrasound Examination in Tumor-Like Formations of the Ovaries
Authors: Stasiv Iryna Dmytrivna ,   Department of Radiology and Radiation Medicine, Ivano-Frankivsk National Medical University, Ivano-Frankivsk, Ukraine,   Iryna Dmytrivna Stasiv,Department of Radiology and Radiation Medicine of Ivano-Frankivsk National Medical University,2 Halytska, 76000, Ivano-Frankivsk, Ukraine, E-mail: irman@meta.ua, Phone: +380976063629, Ryzhyk Valeryan Mykolayovych ,   Department of Radiology and Radiation Medicine, Ivano-Frankivsk National Medical University, Ivano-Frankivsk, Ukraine, Mishchuk Vasyl Hryhorovych ,   Department of General Practice (Family Medicine), Physical Rehabilitation and Sports Medicine, Ivano-Frankivsk National Medical University, Ivano-Frankivsk, Ukraine, Dudiy Petro Fedorovych ,   Department of Radiology and Radiation Medicine, Ivano-Frankivsk National Medical University, Ivano-Frankivsk, Ukraine, Salyzhyn Tetyana Ivanivna ,   Department of Internal Medicine No. 1, Clinical Immunology and Allergology, E.M. Neyka, Ivano-Frankivsk National Medical University, Ivano-Frankivsk, Ukraine
Published: November 2022

Properly diagnosed tumor-like formations of the ovaries facilitate the correct selection of patients who may not require surgery, or choose surgery with minimal access if such intervention is required. Subjective assessment of the features of tumor-like formations with the help of ultrasound diagnostics, including compression elastography, proved to be highly effective in the differential diagnosis of bulky ovarian formations. All tumor-like formations have their sonographic features that allow making a reliable diagnosis of a particular formation. The article reveals data on the diagnostic significance of multiparametric ultrasound imaging in the detection of ovarian tumor-like formations. A detailed sonographic picture of tumor-like formations in B-mode, color, and pulse Doppler mode and compression sonoelastography mode was analyzed. This examination was especially relevant for women of reproductive age, as it depended on the further tactics of treatment of each patient. For all types of tumor-like formations ovaries, a qualitative feature was determined - elastotype on the Ueno scale and the index of stiffness (Strain Ratio) - a quantitative indicator. Follicular cysts, endometrioid and periovarian cysts were found to belong to the 0 elastotype. Cysts of the corpus luteum belonged to the II elastotype on the Ueno scale. The lowest values of the stiffness index were seen in follicular and periovarian cysts, and the highest value was observed in endometrioid cysts. Our results have shown that ultrasound examination of ovarian tumors is an accurate and highly informative method.
Psychological Impact on Maxillofacial Trauma Patients – An Observational Study
Authors: Kishore Jay ,   Bihar Government, Primary Health Center, Sahdei Buzurg, Vaishali, Bihar, India, Vatsa Ritesh ,   Department of Dentistry, Sri Krishna Medical College and Hospital, Muzaffarpur, Bihar, India, Singh Jyotirmay ,   Department of Orthodontics and Dentofacial Orthopaedics, Patna Dental College and Hospital, Patna, Bihar, India,   Dr. Jyotirmay Singh, MDS, PhD, Reader,Department of Orthodontics and Dentofacial Orthopedics,Patna Dental College and Hospital,Patna, Bihar, India. E-mail: drpriyakasture@gmail.com Phone: 91-7999449364, Kumari Minti ,   Department of Public Health Dentistry, Patna Dental College and Hospital, Patna, Bihar, India, Kumar Tanoj ,   Department of Oral Pathology, Patna Dental College and Hospital, Patna, Bihar, India, Bandgar Subhash ,   Department of Prosthodontics, Nair Hospital Dental College, Mumbai, Maharashtra, India
Published: November 2022

Facial disfigurement due to trauma is very common as the face is a prominent part of the body and is susceptible to injuries. A protocol for the diagnosis and intervention for psychological problems of trauma patients should be implemented in the Indian hospitals as they lack policies for assessing the mental status of such patients. This study was conducted to analyze and determine the psychological implications and need for mental health services of maxillofacial trauma patients. Fifty patients with maxillofacial trauma above 18 years of age were included in this study. The assessment was done using the Hospital Anxiety and Depression Scale (HADS) and Trauma Screening Questionnaire (TSQ), which are considered as the standard tools for assessment of psychological disorders post-trauma. We observed psychological stress in 84% of the patients at the baseline, which reduced to 24% after one month at the first follow-up visit and further reduced to 22% at the second follow-up visit. The reduction in the percentage from the first to the second follow-up visit was less significant. However, the change in HADS and TSQ scores was found to be significant, suggesting that the intensity of trauma decreases with the time-lapse. Anxiety, depression, and post-traumatic stress are prevalent in patients with maxillofacial trauma, which may lead to impaired day-to-day life. Our results suggest that there is a need for psychological care in patients with maxillofacial trauma.
Mental Health Disorders During the COVID-19 Outbreak in Cyprus
Authors: Neophytos Stylianou ,   International Institute for Compassionate Care, Nicosia, Cyprus,   Dr. Stylianou Neophytos International Institute for Compassionate Care 24, Ilia Papakyriakou, Nicosia, 2415, Cyprus E-mail: n.stylianou@symponesi.org, Samouti Gregoria ,   International Institute for Compassionate Care, Nicosia, Cyprus, Samoutis George ,   International Institute for Compassionate Care, Nicosia, Cyprus
Published: November 2022

Cyprus has been affected by COVID-19 since March 2019. With a case fatality rate of 2.6% (until June 2020) and the social isolation measures enforced on the population, the population’s mental health has been affected. We aimed to assess the mental health burden of the Cypriot population during the outbreak and to explore the potential influence factors.

Using a web-based cross-sectional survey, we collected data from 216 volunteers regarding demographic data, COVID-19-related knowledge, generalized anxiety disorder (GAD), and major depressive symptoms. The overall prevalence of GAD and major depressive symptoms of the public were 13.89% and 8.33%, respectively. No demographic had shown any statistical significance with GAD. The younger age group of the study showed a statistically significant association with major depressive symptoms when compared to the adult population in both univariate and multivariable analyses.

Our study identified a mental health burden of the Cypriot population, especially the younger age groups. As part of the preparedness for situations as the one we are experiencing and the future impact the pandemic may have on society, interventions should be focused on vulnerable groups of the population to alleviate the psychosocial effects.
Thyroid and Pseudothyroid Dysfunction as a Cause That is Promoting the Relapse of Benign Focal Thyroid Pathology
Authors: Tkachuk Nina Petrivna ,   Department of Surgery No. 1, Higher State Educational Establishment of Ukraine “Bukovinian State Medical University”, Chernivtsi, Ukraine,   Nina Petrivna Tkachuk Higher State Educational Establishment of Ukraine “Bukovinian State Medical University”,137 Golovna Street, Chernivtsi, Ukraine, E-mail: kovalskan@ukr.net Phone: +380660913678;
Published: November 2022

Several studies deal with learning causes stipulating nodular formations in the thyroid tissue, including those occurring against the ground of metabolic disorders of thyroid hormones. Our study’s objective was to determine the peculiarities of thyroid homeostasis disorders in patients suffering from benign nodular thyroid pathology with relapses of the disease and its relapse-free course. For this purpose, 96 female patients suffering from nodular thyroid pathology and 20 without thyroid pathology were examined. In the course of the study, the following were found in patients with benign focal thyroid pathology: disorders of the peripheral conversion of the thyroid hormones, compensatory activation of the hypothalamic-pituitary system evident in increased levels of the thyroid-stimulating hormone, ТSH/fT3 and ТSH/fT4 ratios, increasing titers of the anti-thyroid antibodies which can be hazardous for the risk of development of nodules or reflects the process of thyroid tissue damage; high level of thyroglobulin caused by an increased probability of relapse and rate of nodule growth, an increase of the thyroid gland volume associated with activation of the hypothalamic-pituitary system, increased antibodies titer and thyroid gland damage. Thus, changes of the examined indices in the blood can be used as prognostic markers concerning the relapse of nodule formation in the thyroid tissue.
Periimplant Bone Resorption at the Level of Tilted Implants in SKY Fast & Fixed Restorations
Authors: Mocanu Raluca Gabriela ,   Department of Complete Denture, Faculty of Dental Medicine, “Carol Davila” University of Medicine and Pharmacy,Bucharest, Romania,   Raluca Mocanu, PhD student, Faculty of Dental Medicine, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, E-mail: ralucaistrateg@gmail.com,   All authors have contributed equally, Florica Laurentiu Iulian ,   Private practice, Bucharest, Romania,   All authors have contributed equally, Preoteasa Cristina Teodora ,   Department of Scientific Research Methods-Ergonomics, Faculty of Dental Medicine, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania,   All authors have contributed equally, Meghea Mihaela Daniela ,   Department of Complete Denture, Faculty of Dental Medicine, “Carol Davila” University of Medicine and Pharmacy,Bucharest, Romania,   All authors have contributed equally, Preoteasa Elena ,   Department of Complete Denture, Faculty of Dental Medicine, “Carol Davila” University of Medicine and Pharmacy,Bucharest, Romania,   All authors have contributed equally
Published: November 2022

Implant-prosthetic rehabilitation registers multiple variants, but their short- and long-term evolution has been a frequent concern. This study aimed to evaluate the peri-implant bone resorption at the level of the tilted implants in the SKY fast & fixed restorations, with reference to clinical and treatment parameters. An observational study was conducted on a convenience sample of patients with implant-prosthetic rehabilitation in one or both jaws, according to the SKY fast & fixed protocol (Bredent, Germany). Bone resorption was assessed on panoramic radiography. Other data were collected from the patient’s medical records. Thirty tilted implants were analyzed, 12 of which were in the maxilla and 18 in the mandible. After the follow-up period, both bone resorption (maximum 7 mm) and bone apposition (maximum 8 mm) were observed. There was a tendency for the resorption to be more pronounced in the mandible, in patients where tooth loss was due to periodontal disease, and when implants with length less than 16 mm were used. Resorption was statistically significantly lower when bone addition materials and membranes were used at the extraction socket, and when SKY fast & fixed rehabilitation was performed in both jaws. SKY fast & fixed implant-prosthetic technique, which involves applying a small number of implants, and a fixed prosthesis corresponding to a shortened dental arch, is a viable method of treatment that outcomes the need for complex and expensive surgical interventions, and proves to be beneficial in maintaining the optimal parameters of bone support.
Etiology and Prevention of an Endodontic Iatrogenic Event: Instrument Fracture
Authors: Amza Oana ,   Department of Endodontics, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Dimitriu Bogdan ,   Department of Endodontics, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania,   Bogdan Dimitriu 3, Dr. A. Boicescu Street 050484, Bucharest, Romania Phone: 0040744580012 E-mail: bogdim@gmail.com, Suciu Ioana ,   Department of Endodontics, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Bartok Ruxandra ,   Department of Aesthetics in Dental Medicine, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Chirila Mihaela ,   Department of Endodontics, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
Published: November 2022

Although benefiting from an unprecedented technological evolution, contemporary endodontics is still characterized by the recurrence of retreatments, due to the need to solve quite frequent incidents, accidents, or even failures of primary endodontic treatment. This survey aims to assess both the etiology and the prevention methods of one of the most troublesome endodontic iatrogenies: instrument separation during root canal shaping. The multifactorial nature of this occurrence entails identifying and taking into account all the causal and contributing factors. Their significant number and the possible involvement of any of them, starting with the complexity and variability of the root canals and ending with the technical specifications concerning the nickel-titanium rotary instrumentation system being used, highlight the necessity to develop valid guidelines to avert the occurring of such an upsetting situation.