bluuebunny/crossref_metadata_2025 huggingface dataset:
Kemandirian Anak Usia Dini Dengan Pola Asuh Orang Tua Single Parent yang Demokratis
Authors: Hasanah Melda , Ayub Daeng , Rizkia Alvi Ria
Published: August 2022

Independence is an important thing that needs to be instilled in children from an early age. With children who are accustomed to being independent since childhood, they will carry over into adulthood. Independence in children can be influenced by parenting applied by parents. Single parents have multiple roles that make it difficult to share time with their children. With the use of inappropriate parenting by single parents, it can lead to less than optimal independence in children. This study aims to describe the independence of early childhood with democratic single parent parenting. This study uses a qualitative approach, which was carried out in Segati Village with 3 single mothers with 5 year old children as informants. This research data collection using documentation, observation and interviews. Data analysis with the stages of reduction, presentation and conclusion. The results showed that single parent parents who have multiple roles by applying democratic parenting can instill independence in children from a young age more optimally.

Keywords: Independence, children, democratic parenting, single parent
Minimalisasi Biaya Produksi Sendal Menggunakan Linear Programming:
Authors: Haziziyah Indah , Pardede Akim M.H. , Sihombing Marto
Published: August 2022

The simplex method is a method used to solve linear programming problems with repeated calculations (iterations) that are performed many times until an optimal solution is reached. In solving linear programming problems, it is necessary to determine the constraints and inequalities contained in linear programming. The simplex method can solve linear programming problems involving many inequalities and many variables. Therefore, the purpose of this research is to optimize the production cost of sandals in the Diona Shoes Home Industry. The steps taken to optimize the production cost of sandals include: observing and collecting data, then making a mathematical model, then optimizing production results using the simplex method (iteration), and finally optimizing production results with the Lindo 16.0 software tool.

 Keywords: Diona Shoes, Linear Programming, Simplex Method, Lindo 16.0.
Abnormal Sodium and Chlorine Level Is Associated With Prognosis of Lung Cancer Patients
Authors: L Luo , M Yang , Y Che , K Li , X Wen , G Yang , Y Tan , H Luo , C Wu , Z Fang , W Jiang , W Wang
Published: August 2022

Objective: The imbalance of sodium and chloride ions occurs frequently in patients with lung cancer. However, the correlation between ion concentration change and patients prognosis have not been studied thoroughly. Our research will fill the gap, especially for high ion concentration. Methods: We retrospectively studied inpatients diagnosed with primary NSCLC and treated between May 2015 and July 2017. The basic clinical information and blood test data before and after treatment were collected. According to the clinical reference range of normal ion concentration, the patients were divided into three groups: low, normal and high level. Kaplan-Meier curve was used to analyze the difference of overall survival (OS) prognosis among each group. The correlation between ion concentration and other clinical parameters was further analyzed. Finally, a prognostic nomogram model was established by LASSO-COX method. Results: In the 1237 patients cohort, the median follow-up period was 861 days (range 3-2128 days). Firstly, 6 serum ions were included in the study, and only sodium (Na) and chloride (cl) ions were significantly associated with OS. Low level patients were found nearly just in III-IV stage patients, in contrast, high level patients distribute evenly in all stages. Then, correlation analysis showed that increased Na and cl concentrations were associated with decreased neutrophil number and elevated lymphocyte proportion. Finally, prognostic model analysis showed that cl is a crucial parameter. Conclusion: Serum Na and cl ion concentrations are closely related to the OS of lung cancer patients, and should be considered as clinical prognostic factors.
Open versus minimally invasive sphincter-sparing surgery for rectal cancer: a single-center retrospective cohort study in Peru
Authors: Guevara Jabiles Andres , Berrospi Espinoza Francisco , Chavez Passiuri Iván , Luque-Vásquez Carlos , Payet Meza Eduardo , Baldeón Dante , Caparachín Nanto , Ruiz Figueroa Eloy
Published: August 2022

Objective: The study aimed to describe and compare minimally invasive surgery (MIS) and open surgery for rectal cancer in Peru. Material and methods: A retrospective single-center analysis was performed for all patients who underwent sphincter- sparing surgery for non-metastatic rectal cancer at Instituto Nacional de Enfermedades Neoplásicas in Peru between January 2016 and December 2020. Clinical, perioperative, pathological, and survival outcomes were compared between both groups. A propensity score matching method was used to minimize bias. Results: 162 patients were included in the final analysis. 124 had open surgery and 38 had MIS. Patients, clinical tumour, pathological characteristics, and perioperative were similar between groups after matching. Similar circumferential resection margin (CRM) with optimal quality of the mesorectum (p=1.000) but higher number of lymph nodes resected in open surgery group (p=0.741) was described. The leakage rate was slightly higher in the MIS group (p=0.358) with 10.5%, while the postoperative hospital stay was longer in the open surgery group after matching (p=0.001; OR 95% 5.2 CI: 1.8-15.6). The estimated recurrence-free survival (RFS) and overall survival (OS) at 3 years in open surgery and MIS was 71.8% (95% CI; 0.58-0.89) and 70% (95% CI; 0.56-0.88) (p=0.431) and 77.7% (95% CI; 0.64-0.94) and 88.9% (95% CI; 0.79-0.99) (p=0.5), respectively. Conclusions: Shorter postoperative hospital stay in the minimally invasive surgery group was reported. RFS, OS, and re lar between both groups. This approach is for non-metastatic rectal cancer in referral centers in Peru.
Field Trial Comparison of Techniques of Root Kill on Problem Species
Authors: McNamara Michael
Published: August 2022

Three basic methods of brush control were compared for their control of black locust (Robinia pseudoacacla L.) root suckers and stump sprouts found on the right-of-way. The selective basal method showed the best control of the black locust root suckers. Where the brush was cut, the precut basal method showed better control than the stump treatment method.
DESEMPENHO ECONÔMICO E FINANCEIRO E GOVERNANÇA CORPORATIVA
Authors: Adhmir Renan Voltolini Gomes  , Mello Gilmar Ribeiro de
Published: August 2022

O presente estudo objetivou analisar as chances do desempenho econômico e financeiro determinar as práticas de governança corporativa do próximo exercício. A base teórica aborda desde a teoria da agência, a governança corporativa e seus mecanismos, bem como o desempenho econômico e financeiro das empresas. O procedimento metodológico possui uma abordagem quantitativa com o uso de regressão logística. A amostra refere-se as empresas que compuseram o Índice Bovespa no ano de 2016. Os resultados demonstraram coeficientes estatisticamente significantes para o retorno sobre o ativo e os dividendos pagos. Deste modo, quando as empresas aumentam o seu desempenho, os principais podem exigir as práticas de governança dos agentes com a intenção de diminuir os riscos. E dispendem recursos para certificar-se que os resultados obtidos são confiáveis, por meio de práticas governança. Além disso, os resultados deixam a implicação teórica sobre a associação entre governança corporativa e o desempenho econômico e financeiro também no mesmo período de tempo.
Workshop Teknik Kelompok sebagai Strategi Efektif Meningkatkan Kompetensi Guru dalam Penyusunan Instrumen Penilaian
Authors: Purnama Basuki Jaka
Published: August 2022

The competence of teachers in constructing instruments of assessment greatly affects the accuracy of measuring the achievement of students’ competence. This study aims to: (1) improve the competence of teachers in preparing assessment instruments and (2) obtain the information of the workshop implementation on improving the teachers of SMA Negeri 1 Kalasan competence in developing assessment instruments. This research is an action research which was conducted in semester 1 of the 2020/2021 academic year for 4 months with 10 teachers as the research subjects. This action research used the Kemmis and Taggart models with two cycles, each cycle consisted of two meetings with the stages of planning, action, observation, and reflection. The data collection was done through observation and product assessment. The data analysis was carried out by scoring and calculating the final score of the observed and assessed activities. The results of the study indicate that the workshop can improve the competence of the teachers in constructing assessment instruments in the form of a grid of questions and items. This was proven by an increase in the ability to compose a grid of questions from 75.88% (poor) in the first cycle to 88.25% (able) in the second cycle and an increase in the ability to construct the items from 77.42% (poor) in the first cycle to 88.89% (able) in the second cycle. It means that the teacher's competence has met the indicator of a successful action at 80%. Based on these results, it can be concluded that the workshop has really improved the competence of the teachers of SMA Negeri 1 Kalasan in constructing the grids and test items.
Matematik Ders Kitaplarında Tam Sayılarla Çarpma ve Bölme İşlemleri Nasıl Öğretiliyor: Türkiye, ABD ve Kanada Karşılaştırması
Authors: ŞEN Emine Özgür
Published: August 2022

Bu araştırmada matematik ders kitaplarında tam sayılarla çarpma ve bölme işlemlerinin nasıl öğretildiği incelenmiştir. Bu bağlamda, Türkiye, ABD ve Kanada matematik ders kitaplarında tam sayılarla çarpma ve bölme işlemlerinin nasıl sunulduğu incelenmiş ayrıca konu içeriğinde verilen örnek ve problemlerin analizi değerlendirilmiştir. Nitel olarak tasarlanan çalışmanın yöntemi doküman incelemesidir. Veri toplama aracı olarak Türkiye, ABD ve Kanada’nın matematik ders kitapları kullanılmıştır. Verilerin analizi içerik analiz yöntemi kullanılarak çözümlenmiştir. Araştırmada, ders kitaplarında tam sayılarla çarpma ve bölme işlemi öğretiminde sunulan problemlerin büyük çoğunluğunun hesaplama, temel bilgi ve becerileri doğrudan uygulama, kapalı uçlu cevap ve matematiksel olduğu sonucuna ulaşılmıştır. Kanada matematik ders kitabında tartışma, yorumlama, bağlantı oluşturma, yansıtıcı düşünme, açık uçlu cevap, gerçek ve otantik bağlam problemleri diğer ders kitaplarına oranla daha fazla olduğu tespit edilmiştir. Türkiye matematik ders kitabındaki problemler ise hesaplama, temel bilgi ve becerileri doğrudan uygulama, kapalı cevap ve matematikseldir. Ayrıca, tam sayılarla çarpma ve bölme işlemi öğretimde tüm ders kitapları sayma pulları ve sayı doğrusu modelini kullanmıştır. Ancak sadece Kanada matematik ders kitabı tam sayılarla çarpma ve bölme işlemini öğretiminde model kullanımını ayrıntılı olarak ele almıştır.
EFEKTIVITAS PASTA GIGI BAKING SODA DAN NON BAKING SODA TERHADAP PENURUNAN STAIN PADA PEROKOK
Authors: Nuraskin Cut Aja , Reca Reca
Published: August 2022

Many people do not realize that smoking habits can affect the level of dental and oral hygiene, smoking causes abnormalities of the tongue, gums, oral mucosa, palate in the form of nicotinic stomatitis, fungal infections, and causes discoloration of the te eth. Sodium bicarbonate is a chemical compound with the formula NaHCO3 belonging to the salt group and is often found in the form of white powder crystals. Where the content of sodium bicarbonate can remove stains on smokers. The purpose of this study was to determine the effectiveness of the use of toothpaste containing baking soda and non-baking soda to reduce stains in smokers.This type of research is analytic with a quasi-experimental method. The sample was used as many as 62 people then divided into 2 groups which were then checked for staining conditions before and after the use of toothpaste containing baking soda and non -baking soda.The results showed that the average tooth staining before and after brushing using toothpaste containing baking soda showed a decrease in staining on the Lobene intensity measurement as much as 0.324, lobene area as much as 0.217, combined as much as 0.541, with p = 0.000 < = 0, 1. While the average tooth staining before and after using non -baking soda toothpaste there was a decrease in stain on Lobene intensity measurements as much as 0.043, Lobene area as much as 0.016, combined as much as 0.059 , with p value = 0.116 > = 0.1.This study concluded that the use of toothpaste containing baking soda was more effective than non-baking soda toothpaste to reduce the stain index in smokers. It is suggested that the public can use toothpaste containing baking soda as an alternative to remove stains on the teeth, and pay more attention to the status of oral hygiene.
HUBUNGAN PERAN ORANG TUA DENGAN STATUS KARIES GIGI PADA MURID SDN 1 JEUMPET KECAMATAN DARUL IMARAH KABUPATEN ACEH BESAR
Authors: Zahara Elfi , Nisa Warzaton
Published: August 2022

Parents, especially mothers, play an important role in maintaining dental health to see the development and growth of children's teeth. Currently, tooth decay in children is considered a natural thing, so parents think that they do not need to deal with it. From the initial data from interviews with parents of students, parents still lack a role in maintaining the health of children's teeth and mouth. And the results of the dental caries examination of 9 students who were examined on average had dental caries with a category of 5.2 (high).The purpose of this study was to determine the relationship between the role of parents and dental caries status in students at SDN 1 Jeumpet, Kec. Darul Imarah, Aceh Besar District. This type of research is analytic with cross sectional study method and uses a questionnaire as an instrument. The sampling technique in this study was using a saturated sampling technique, because all the population was sampled, amounting to 35 students and 35 parents of students at SDN 1 Jeumpet.The results showed that the role of parents in the good category had the most dental caries status in the low category as many as 3 students (60.0%), the role of parents in the moderate category had the most dental caries status in the moderate category as many as 9 students (64.3% ) and the role of parents in the less category having the highest dental caries status in the high category was 7 students (43.8%). The results of the statistical test obtained P < 0.001 from the value of = 0.05 because P = 0.001 < = 0.05.Based on the results, it can be concluded that there is a relationship between the role of parents and the status of dental caries. Based on the conclusion, it is suggested that parents can increase their roles as educators, motivators, facilitators in maintaining children's oral and dental health.
Zanubrutinib (Brukinsa)
Authors: CADTH
Published: August 2022

CADTH recommends that Brukinsa (zanubrutinib) should not be reimbursed by public drug plans for the treatment of adult patients with mantle cell lymphoma (MCL) who have received at least 1 prior therapy.

While evidence from 2 clinical trials showed a response in patients treated with Brukinsa, there is uncertainty in how well patients respond to Brukinsa and how Brukinsa compares to other treatment for MCL.

There was no evidence demonstrating improvement in quality of life, since there was no quality of life evidence collected in either clinical trial.

It is unclear whether Brukinsa meets the following needs identified by patients: faster remission and longer life, disease and symptom control, better quality of life, and fewer side effects.
Deteksi Dini Varian Covid-19 Dengan Metode CBR-AHP Dan Sorgenfrei
Authors: Darmawan Mohamad Riza , Wibisono Setyawan
Published: August 2022

The case fatality rate caused by Covid-19 in Indonesia is around 2.9%. The death rate by age group is from all Covid-19 patients who died, including 0.5% aged 0-5 years, 0.5% aged 6-18 years, 2.8% aged 19-30 years, 12.7 % were aged 31–45 years, 36.8% were aged 46–59 years, and 46.7% were aged 60 years and over. With the large number of cases that occurred in Indonesia, it turned out to be due to the lack of proper handling of the early symptoms of the Covid-19 virus. To overcome this, it is needed as a tool for early detection of the Covid-19 variant by using the CBR-AHP expert system with the Sorgenfrei algorithm. The results of the consultation for the early detection of the Covid-19 variant were obtained from the highest similarity value of Sorgenfrei. Of all the variants found above, the highest similarity value of Sorgenfrei is Omicron with a similarity of 1,000. Omicron has the highest value because it has a value of a, which is the same symptom between old cases and large new cases.
OCTOPUS database (v.2)
Authors: Codilean Alexandru T. , Munack Henry , Saktura Wanchese M. , Cohen Tim J. , Jacobs Zenobia , Ulm Sean , Hesse Paul P. , Heyman Jakob , Peters Katharina J. , Williams Alan N. , Saktura Rosaria B. K. , Rui Xue , Chishiro-Dennelly Kai , Panta Adhish
Published: August 2022

Abstract. OCTOPUS v.2 is an Open Geospatial Consortium (OGC) compliant web-enabled database that allows users to visualise, query, and download cosmogenic radionuclide, luminescence, and radiocarbon ages and denudation rates associated with erosional landscapes, Quaternary depositional landforms, and archaeological records, along with ancillary geospatial (vector and raster) data layers. The database follows the FAIR (Findability, Accessibility, Interoperability, and Reuse) data principles and is based on open-source software deployed on the Google Cloud Platform. Data stored in the database can be accessed via a custom-built web interface and via desktop geographic information system (GIS) applications that support OGC data access protocols. OCTOPUS v.2 hosts five major data collections. CRN Denudation and ExpAge consist of published cosmogenic 10Be and 26Al measurements in modern fluvial sediment and glacial samples respectively. Both collections have a global extent; however, in addition to geospatial vector layers, CRN Denudation also incorporates raster layers, including a digital elevation model, gradient raster, flow direction and flow accumulation rasters, atmospheric pressure raster, and CRN production scaling and topographic shielding factor rasters. SahulSed consists of published optically stimulated luminescence (OSL) and thermoluminescence (TL) ages for fluvial, aeolian, and lacustrine sedimentary records across the Australian mainland and Tasmania. SahulArch consists of published OSL, TL, and radiocarbon ages for archaeological records, and FosSahul consists of published late-Quaternary records of direct and indirect non-human vertebrate (mega)fauna fossil ages that have been systematically quality rated. Supporting data are comprehensive and include bibliographic, contextual, and sample-preparation- and measurement-related information. In the case of cosmogenic radionuclide data, OCTOPUS also includes all necessary information and input files for the recalculation of denudation rates using the open-source program CAIRN. OCTOPUS v.2 and its associated data curation framework allow for valuable legacy data to be harnessed that would otherwise be lost to the research community. The database can be accessed at https://octopusdata.org (last access: 1 July 2022). The individual data collections can also be accessed via their respective digital object
identifiers (DOIs) (see Table 1).
Islet: interpolation semi-Lagrangian element-based transport
Authors: Bradley Andrew M. , Bosler Peter A. , Guba Oksana
Published: August 2022

Abstract. Advection of trace species, or tracers, also called tracer transport,
in models of the atmosphere and other physical domains
is an important and potentially computationally expensive part of a model's dynamical core.
Semi-Lagrangian (SL) advection methods are efficient because
they permit a time step much larger than the advective stability limit
for explicit Eulerian methods
without requiring the solution of a globally coupled system of equations as implicit Eulerian methods do.
Thus, to reduce the computational expense of tracer transport,
dynamical cores often use SL methods to advect tracers.
The class of interpolation semi-Lagrangian (ISL) methods contains potentially extremely efficient SL methods.
We describe a finite-element ISL transport method that we call the
interpolation semi-Lagrangian element-based transport (Islet) method,
such as for use with atmosphere models discretized using the spectral element method.
The Islet method uses three grids that share an element grid:
a dynamics grid supporting, for example, the Gauss–Legendre–Lobatto basis of degree three;
a physics parameterizations grid with a configurable number of finite-volume subcells per element;
and a tracer grid supporting use of Islet bases with particular basis again configurable.
This method provides extremely accurate tracer transport
and excellent diagnostic values in a number of verification problems.
Manajemen Kearsipan Digital dalam Upaya Meningkatkan Mutu Sistem Penyimpanan Dokumen Kepegawaian di Kota Banda Aceh: Hambatan dan Tantangan
Authors: Aulia Adinda , Kurniawan Rudi
Published: August 2022

The quality of staffing documentation stored electronically at the Aceh Public Works and Spatial Planning Office of Banda Aceh City is unsatisfactory. This study aims to find out how the process of managing archives management improves the quality of the employee document storage system by using electronics as a storage medium. The data techniques employed were observation, interviews and documentation. The type of this research is qualitative. The results of this study can be reported that the obstacles that occur in the Aceh Public Works and Spatial Planning Office of Banda Aceh City are: (1) Lack of understanding of the importance of archives by members of the organization; (2) It has not been carried out or cultivated regarding the guidelines for borrowing archives so that every employee borrows files without clear regulations; (3) There is no planning regarding the shrinkage of archives so that the libraries are piling up and are no longer accommodated. It is hoped that government agencies will be able to improve the quality of documentation storage systems using electronic media and utilize employees who are reliable and capable of operating computers properly.
PERAN MEDIASI MEANING IN WORK DAN PERSONAL RESOURCES PADA PENGARUH TRANSFORMATIONAL LEADERSHIP TERHADAP WORK ENGAGEMENT
Authors: Larasati Putri Hardanti Gita , Srimulyani Veronika Agustini , Farida Florentina Anif
Published: August 2022

Salah satu dampak pandemi Covid-19 adalah perubahan pada waktu kerja dan perubahan pola kerja yang harus disikapi secara positif oleh manajer dan karyawan agar tetap bekerja secara professional dan berpikiran inovatif dalam bekerja. Pemimpin harus berperan aktif menyiapkan karyawan menghadapi perubahan tersebut, sehingga tetap terlibat aktif, bersemangat, dan produktif meskipun banyak kendala selama masa pandemi ini. Pandemi tersebut menjadi momentum penting bahwa work engagement sangat berharga bagi perusahaan. Penelitian ini bertujuan menganalisis pengaruh transformational leadership terhadap work engagement melalui meaning in work dan personal resources sebagai mediasi. Sampel penelitian ini berjumlah 134 karyawan tetap CV Industri Kreatif Madiun. Teknik analisis data menggunakan analisis statistik deskriptif dan path analysis. Hasil penelitian menunjukkan bahwa: 1)transformational leadership berpengaruh signifikan positif terhadap work engagement; 2) transformational leadership berpengaruh sigifikan positif terhadap meaning in work; 3) meaning in work berpengaruh signifikan positif terhadap work engagement; 4)meaning in work sebagai partial mediating pengaruh transformational leadership terhadap work engagement; 5) transformational leadership berpengaruh signifikan positif terhadap personal resources; 6) personal resources berpengaruh signifikan positif terhadap work engagement; 7) personal resources sebagai partial mediating pengaruh transformational leadership terhadap work engagement.
Molecular Docking Studies of Interaction Curcumin against Beta-secretase 1, Amyloid A4 Protein, Gamma-secretase and Glycogen Synthase Kinase-3β as Target Therapy for Alzheimer Disease
Authors: Rizki Syaban Mokhamad Fahmi , Muhammad Rislan Faiz , Adnani Basyar , Ami Putra Gumilar Fardhani , Erina Erwan Nabila , Dita Arviana Safira , Krisnayana Agung Dwi , Kurniawan Dedy Budi
Published: August 2022

Alzheimer's disease (AD) is the most common form of dementia. In several studies we reviewed, curcumin can inhibit formation, extension, and destabilization of Amyloid A4 protein. Aim: This study aims to prove the consistency of curcumin as a candidate therapy for Alzheimer's disease using in silico approach. Methods: Biomolecular experimental study was conducted using in silico method supported by protein database, Pymol, Discovery studio, and PyRx software. A comprehensive literature search was conducted to found the potential target for Alzheimer's disease. We found Beta-secretase 1, Amyloid A4 protein, Gamma-secretase, and Glycogen synthase kinase (GSK)-3β as a protein target. Pharmacokinetic analysis was conducted based on the Lipinski Rule of Five criteria on the Lipinski Rule of Five websites and using the PreADMET website. Results: From the pharmacokinetic analysis, curcumin had met all the Lipinski and PreADMET criteria. The HIA and plasma binding test results showed 94.4% and 88%, which represent a good pharmacokinetic and bioavailability profile as a drug. GSK-3β had the strongest binding affinity with curcumin as recorded as -8.3 kcal/mol compared with the other four protein targets in this analysis. Conclusion: The strongest binding affinity between curcumin and GSK-3β reveals the potential target protein for Alzheimer's Disease therapy. Those interactions represent the potential involvement in the pathogenesis of Alzheimer's Disease with a modification of the additional sites on the tau molecule. This drug candidate discovery shows a preferable pharmacokinetics and bioavailability substance profile with a promising target through the Structure-based Drug Design (SBDD) approach. However, curcumin ability for BBB penetration still needs to be modified to improve its pharmacokinetic properties for becoming a novel Alzheimer's disease drug.
The use of Microvit A in the Form of a Synthetic supplement for Metabolic Processes and Localization of Protein Substances
Authors: Valoshin A.V. , Glazkov A.V.
Published: August 2022

The purpose of this research is to study the present data on the effect of different dosages of vitamin A (retinol acetate) on the metabolism and localization of protein substances (protein) in the body of experimental animals (fattening bull calves). The authors use the concept of conversion of protein substances (protein) from the diet feed into the main nutrients of the edible part of the carcass (cuts) of bull calves fed on diets with pulp granules. The authors evaluate the morphological parameters of the animal after slaughter. For the experiment, 45 heads of black-and-white bull calves at the age of 12-13 months with a live weight of 270-290kg were selected. They were distributed according to the principle of similarity into three experimental groups of 15 heads each. The groups differed in diet, namely, an increase in the dosage of vitamin A in the second and third groups by 25 and 30% relative to the first group. According to the slaughter data and the study of the morphological composition of carcasses, the authors found that it was necessary to introduce vitamin A preparation into such diets. In this experiment, the authors used retinol acetate with the biological activity of 1 mln international units in 1 g, so that their content in the diets was 23-24 thousand international units per 100kg of live weight (optimally derived dose, depending on the live weight of the animal during the experiment). This contributed to an increase in the average daily weight gain of bull calves by 11.7% and an increase in carcass weight by 9.2%, including flesh weight by 11.1%. In the carcass flesh, the protein content increased by 15.4%, fat by 15.2%, and energy by 8.2%. The conversion rate of protein substances (protein) of the feed into the edible protein of the flesh of the carcass increased by 1.33% and the energy of the feed by 1.2%.
Immunological and Enzymatic study of Staphylococcus aureus Bacteria and fungi isolated from oral cavity
Authors: Khaleefa Abbas Maysoon , Rammadan Abdul Fatima , H. Rasool Khetam
Published: August 2022

The current work aimed to study the propagation of Staphylococcus aureus and Candida sp. and. in oral cavity of the human, and their effective on innetimmune response and to describe the biochemical &kinetic properties of PLB from the Staphylococcus aureus. and asporogenous yeast C. tropicalis. The study included 25 patients, ages (12-65) years, with periodontal diseases and at least two sites with probing depth ≥ 3 mm. Participants' data were assessed individually. A sample is taken from the oral cavity (mucous membrane, tongue and cheek) with a sterile swab. Among all the patients studied, (16) 64% showed Staphylococcus in the oral cavity while Streptococcus sp (3) 12% showed candidiasis in the oral cavity and (5) 20 % of other bacteria(1) 4% in the oral cavity. The effect of microbial inflammation on the multidirectional secretion of interleukin (IL) -10, IL-6 has been studied in patients with oral cavity infections. Samples and wash swabs were taken from 25 healthy patients and 25 patients. The supernatant fractions of IL-6 and IL-10 were examined by commercial ELISAs. Analysis of interleukin levels in the two groups with the Mann-Whitney test.IL-6 levels various significantly between the patients, the control group, and the control groups. Median levels of IL-10 in both groups were uniformly low but the mean levels were not statistically different. The observed change in bacterial flora that is characteristic of stomatitis does not enhance or suppress oral levels of IL-6 and IL-10. Staphylococcus aureus, and Candida tropicalis have been isolated oral cavity and under the periodontal sinuses infection. It was filtered 2.5 fold at40 ºC from a culture broth and has an estimated molecular mass of 50kDa.The enzyme was two pH targets, one acid (pH 4.0) and other alkaline (pH 7.5). At acidic pH the enzyme showed a higher affinity for all tested phospholipids without metal ions while its affinity affected by the presence of metal ions at alkaline conditions and the enzyme activity inhibited by Fe3+ and Hg2+.
YAĞ ASİTLERİNİN TİP 2 DİYABET GELİŞİMİ ÜZERİNE ETKİLERİ
Authors: ÖZYILDIRIM Caner
Published: August 2022

Tip 2 diyabet, Dünya genelinde önemli bir nüfusu etkileyen, morbidite ve mortalite riskini artıran metabolik bir hastalıktır. Tip 2 diyabetin gelişiminde genetik ve çevresel faktörlerle birlikte beslenme alışkanlıkları da önemli bir rol oynamaktadır. Son yıllarda özellikle yağ asitlerinin tip 2 diyabet gelişimi üzerine etkileri çalışmalara konu olmuştur. Diyetle alınan toplam yağ miktarına ek olarak yağ asidi örüntüsünün de tip 2 diyabetin gelişme riskinde önemli bir rol oynadığı düşünülmektedir. Bu derleme makalede, yağ asitlerinin insülin direnci ve tip 2 diyabet gelişimi üzerindeki rolünün güncel literatüre dayalı olarak tartışılması amaçlanmıştır.
Palliative Care for the Elderly in the Healthcare System: A Scoping Review
Authors: Velloso Isabela Silva Câncio , Caram Carolina da Silva , Almeida Isabela Rodrigues Pego de , Souza Maria José Silva , Silva Matheus Henrique , Galdino Carolina Sales
Published: August 2022

Objective: To map the scientific evidence related to the organization of palliative care practices provided for the elderly in the Healthcare System. Materials and methods: This is a scoping review following the Joanna Briggs Institute’s method. The search was conducted in the PubMed, Cinahl, Web of Science, Scopus, VHL/Lilacs, Embase, and Cochrane databases, identifying 1,150 articles managed using the Endnote software. After the selection, the study sample consisted of 12 articles. The data were organized in Microsoft Excel spreadsheets, submitted to descriptive analysis, and discussed with the literature. Results: The relevance of palliative care practices for older adults to be organized in the Healthcare System was noted, focusing on primary healthcare, at home, and interdisciplinary coordination. However, there is still a fragmented offer of this care with limited considerations regarding the challenges and possibilities of its effectiveness. Conclusions: The mapping of scientific evidence on the subject shows that discussions regarding the insertion of palliative care in the Healthcare System are modest. The studies explore the role of primary care as the organizer of these practices, although in a fragmented perspective, with limited coordination between the Healthcare System services.
Rezension von: Wolff, Victoria, Gast in der Heimat
Authors: Ferchl Irene , Wolff Victoria
Published: August 2022

Victoria Wolff: Gast in der Heimat. Roman. Hrsg. und mit einem Nachwort von Anke Heimberg. AvivA Verlag Berlin 2021. 331 Seiten mit vier Fotos. Gebunden 22 €. ISBN 978-3-949302-00-8
Endokrin Bozuculara Maruziyetin Azaltılmasına Dair Öneriler
Authors: Aydın Mehmet Emin
Published: August 2022

Endocrine disrupting chemicals are getting more attention in recent years. Endocrine disrupting chemicals released to environment threaten the life of living organisms in environment by bioaccumulating in environment and ecosystem. In this work endocrine disrupting chemicals, their source to release environment are reviewed. Especially, industrial wastewaters run off waters from industrial areas and residential areas, leachates and drainage waters from solid waste disposal sites, run off waters and drainage waters from agricultural lands are important sources that discharge endocrine disruptors to environment. Information about risk assessment procedures for the release of endocrine disrupting chemicals to environment are given as well as procedures followed to regulate or limit the release of such chemicals into environment. Some result from the research carried out about endocrine disrupting chemicals in environment, in foods and human milk samples were also given. Some proposals were made to reduce exposure to endocrine disrupting chemicals of human and other organisms in environment.
Endokrin Bozucu Maruziyetinin Azaltılmasına Yönelik Strateji ve Öneriler: Beslenme Bazlı Tüketici Strateji ve Önerileri
Authors: Demirel Zehra Büyüktuncer
Published: August 2022

Endocrine disrupting chemicals, which are exposed to increasingly in modern life conditions, can affect the health across the lifespan, from the intrauterine period to elderly. Research associates the exposure to endocrine disrupting chemicals with metabolic diseases such as obesity, diabetes, cardiovascular diseases, thyroid diseases, several types of cancer, neurological diseases, reproductive health disorders and childhood developmental problems. Diet has been recognized as one of the main sources that mediates the exposure to endocrine disrupting chemicals. In fact, diet can control endocrine disruptor exposure in three stages. First, the modification in the content of diet and alterations of some behaviors related to nutrition can reduce the total amount of endocrine disrupting chemicals taken into the body. Second, the accumulation of endocrine disrupting chemicals in the body can be partially prevented by the minor dietary modifications. Last, dietary bioactive food components can control the some major mechanisms that activated by the endocrine disrupting chemicals, taken into the body and accumulated in the organs, and thus can prevent the potential damage. At these three stages, five main dietary strategies can be followed for reducing the exposure and efficacy of endocrine disrupting chemicals. These include: raising awareness of dietary endocrine disrupting chemicals; the modification of diet; changing the preferences for food supply; adapting the practices for food preparation, cooking and storage; and maintaining ideal body weight. This chapter has defined the dietary exposure to endocrine disrupting chemicals, and discussed the five main dietary strategies for reducing the exposure to these chemicals.
Success Rate of the Students of National Sports Academy “Vassil Levski” in the Conditions of the COVID-19 Pandemic
Authors: Miladinov Ognyan , Kuleva Milena , Konchev Mihail
Published: August 2022

The article focuses on studying the success rate of NSA “Vasil Levski” students in the period of distance semester examinations in the conditions of the COVID-19 pandemic. The average exam scores between in-person and remote examination periods are compared. The following indicators were examined: the number of examinations held and the number of examinations passed by students; distribution in absolute and relative values of the scores obtained in the range according to the Bulgarian assessment scale; averages of the scores obtained. It has been found that the distance learning platform virtual.nsa.bg offers favorable conditions for quality online exams, which allow obtaining grades adequate to the knowledge shown by the examinees. The methodology by which test exams are created in the platform, and the security mechanisms developed when conducting exams significantly reduce the opportunities for examinees to artificially increase their grades without having demonstrated the required knowledge.
Benchmarking for Development of Speed and Power Characteristics
Authors: Ignatova Darinka , Iliev Alexander
Published: August 2022

The aim of the study was to examine the development of speed and strength dynamics of motor characteristics in 15-16-year-old volleyball players in five training sessions per week for a period of one year and the application of objective tools for its assessment differences in motor potential between the beginning of the study period and one year later, at the end of the study. Methods: Objects are specific indicators measured by objective tools, as well as their systematization and analysis. Results: In the period from September 2020 to July 2021, a measurement of the motor potential of high school students in the education system was conducted. Conclusions: To derive the relationship between the indicators, an analysis of the dynamics was applied by mathematical and statistical processing to derive coefficients of variation and establish the probability for the p-value, as well as to measure students’ criteria.
Myrtaceae de ocorrência no Cerrado: Contribuições e avanços
Authors: Lima Ribeiro Charles , De Castro Peixoto Josana
Published: August 2022

A importância da família Myrtaceae está apresentada em sua presença nos mais diversos biomas do neotrópico. Com distribuição pantropical possui uma elevada biodiversidade nas mais distintas fitofisionomias do Cerrado. Este bioma que vem ao longo do tempo com representações de perda expressiva de biodiversidade florística reforça a necessidade de pesquisas sobre as floras das diferentes famílias botânicas. Neste sentido, este estudo assim, buscou pontuar brevemente os gêneros de ocorrência de Myrtaceae no Cerrado, como uma forma de atrair mais a atenção para estudos e levantamentos desta família botânica neste mosaico de diversidade biológica. Por meio de um levantamento bibliográfico integrativo, explorativo e descritivo, utilizando as seguintes bases de dados científicas: PUBMED, Web of Science, SciELO, utilizando os seguintes descritores: Cerrado, Myrtaceae e cada um dos gêneros; possuindo como referência base Rezende et al., 2008. Conclui-se que esta família botânica possui ampla distribuição no Cerrado, no entanto, ainda precisa ser melhor explorado. Que a falta de conhecimento de suas potencialidades e relações serve como um ponto importante que leva a extinção de um número cada vez maior de espécies e que observando a realidade que o bioma apresenta, há uma necessidade de estudos e de adoção de medidas preservacionistas e conservacionistas em nível de espécie, gênero, família, bioma, contemplando as relações únicas que apresentam com cada fitofifionomia do Cerrado.
Terapi Bermain Untuk Meningkatkan Kekuatan Motorik dan Kognitif pada Lansia Binaan Stikes Bala Keselamatan Palu di Kota Palu
Authors: Emilia Ni Luh , Susanto Denny , Anggreyni Meilin , Sarman Juliana Neng Rifka
Published: August 2022

The age group with the fastest growth in the world today is elderly. The health problems experienced by the elderly are varied, such as cognitive disorders and physical or motor problems. Various efforts have been made to restore this condition, one of them is play therapy. The purpose of this community service is to provide play therapy to improve motor and cognitive strength to the elderly that are fostered by Stikes Bala Keselamatan Palu which is located in Palu City. The method in this activity was done by interviewing, observing and running a questionnaire to measure cognitive of the elderly using the MMSE (Mini Mental State Examination) questionnaire and to measure the client's motor strength, it was used an assessment of muscle strength then the elderly was divided into several small groups with 5 types of games or activities which will be carried out alternately. The results obtained were that 24 elderly who were willing to take part in play therapy activities with MMSE results data, there were 21 elderly who got an average score of < 21 which means that the elderly have cognitive impairment and the average muscle strength of the elderly has a value of 4 which means there were still lots of elderly who have muscle weakness. After the play therapy was carried out, the elderly seemed active, enthusiastic and very happy with this activity. It is recommended that the health workers, especially community health center, can add this play therapy to the elderly integrated services post program.
A study of antioxidant enzymes on experimental epileptic rat models induced by kainic acid excitotixicity
Authors: Praba Mary Antony , Ganesh Kavitha , Hasan Tabinda , Venkataramaniah Venkataramaniah
Published: August 2022

The word neurodegeneration rightly refers to the degenerative changes in nerve cell structure and so in its functions too. The main characteristics of these neurodegenerative disorders are relentless progression and decline in cognition. Epilepsy is one of the neurodegenerative disorders that affects a major portion of people around the world and the common form of focal epilepsy is Temporal lobe epilepsy (TLE). According to researchers the major cause for nerve cell degeneration is the excess production of free radicals. Preventing their action or quenching them will make a big deal in preventing neurodegeneration. As research work in relation to neurodegeneration is very much limited in India, we aimed one as an initiative. As herbs are always well known for their antioxidant activity with negligible side effects, we planned to apply one of the well-known herb, Acorus calamus and studied the potency of it in maintaining the antioxidant enzyme levels. The aim of this study in particular is to analyze the preventive role of Acorus calamus and its active ingredient Beta asarone in neurodegeneration than treating neurodegeneration in epileptic rat models. For the same, we selected eight groups of animals.
Impact of National Health Service on the United Kingdom Health System
Authors:   Independent Researcher, Hong Kong, China, Law Siu-Kan
Published: August 2022

National Health Service (NHS) is a health system in the United Kingdom. It was set up in 1948 and provided by charities and voluntary hospitals, private medical clubs, and occupational medical services. What is the relationship between NHS and healthcare? This present article discusses the background of a health service organization, financial management, the role of a private sector, its finance and provision, also current issues and challenges, as well as a brief comparison with the Hong Kong health system.
Analysis of some factors and COVID-19 mortality in the population of 0 to 24 years in 29 countries: open schools could be a protection
Authors: Gil Jesus D. C. , Vargues-Aguiar Pedro M.
Published: August 2022

Background. It is limited literature on the possible factors related to mortality by COVID-19 in minors. Children and young people are generally considered vulnerable, especially in low-income countries, whereby consistent evidence must arise to protect them and avoid mortality. Methods. A multiple linear regression model was fit to evaluate the relationship between deaths per 100,000 inhabitants and pandemic containment policies, the duration of totally closed schools, and GDP in 29 countries under study. Results. Linear regression analysis shows that the association between deaths per 100k and the number of weeks of closed schools had a coef B=0.355, [CI 0.010; 0.699], and it is statistically significant (P-value =0.044). Similarly, the association between deaths per 100K and GDP was -0.001, [CI -0.003; 0.001], and is not statistically associated (P-value 0.633). Conclusions. This study suggests that open schools could be a protective space for COVID-19 mortality in the child and youth population and that each country should implement studies on the subject at the local level.
Prospective biological control agents for regulation of population of Clostera fulgurita (Walker) on Poplar in Punjab
Authors: Sangha K. , Sohi A.
Published: August 2022

Population of Clostera fulgurita (Walker) can be regulated by natural enemies. Canthecona furcellata Wolff (Hemiptera: Pentatomidae), a predatory bug and Aleoides percurrens Lyle (Hymenoptera: Braconidae), larval parasitoid have potential in regulating the population of this defoliator. Both these biocontrol agents are host density dependent. Temperature range of 20-25oC for Aleoides and 15-20oC for Canthecona is optimum for the development of their population. Adult longevity of Aleoides was more during August-October with maximum parasitisation during October-November, 2003.
Forward Head Posture in Young Adults: A Systematic Review
Authors: Arooj Ayesha , Aziz Aamir , Khalid Fariha , Hussain Iqbal Muhammad , Binte Ashfaq Huda
Published: August 2022

A recent study shows that almost 78% of population have its neck in working position within 24 hours causing continuous stress on neck and shoulders which is forcing the neck in anterior or forward head posture. This may lead to upper back tightness and muscle spasm causing nagging to sharp pain. Hence, cervical pain and neck pain getting more attention. This study is designed to narratively review the prevalence of forward head posture in young adults Methods: A structured search on literature was done through various electronic and print data bases such as: Pubmed, cinhal, google scholar, science direct, cochrane library and scopus. Those studies were included in which age ranged from 20 to 45 years. Young adults from any profession were included. Those studies were excluded in which forward head posture was reported due to any systemic issue Results: A total of 120 studies had gone through in which 65 studies were short listed and on further review only 4 studies were included as they fit in proper methodology and hence, reviewed and reported. Studies reported a considerable variation in the prevalence with the clear greater incidence Conclusions: Forward head posture is a commonly seen disorder among young adults. Investigations and interventions in time along with knowledge of postural correction can deal with this raising problem.