bluuebunny/crossref_metadata_2025 huggingface dataset:
The Phenotype and Genotype of Mevalonate Kinase Deficiency: A Series of 114 Cases From the Eurofever Registry
Authors: ter Haar Nienke M. , Jeyaratnam Jerold , Lachmann Helen J. , Simon Anna , Brogan Paul A. , Doglio Matteo , Cattalini Marco , Anton Jordi , Modesto Consuelo , Quartier Pierre , Hoppenreijs Esther , Martino Silvana , Insalaco Antonella , Cantarini Luca , Lepore Loredana , Alessio Maria , Calvo Penades Inmaculada , Boros Christina , Consolini Rita , Rigante Donato , Russo Ricardo , Pachlopnik Schmid Jana , Lane Thirusha , Martini Alberto , Ruperto Nicolino , Frenkel Joost , Gattorno Marco ,   for the Paediatric Rheumatology International Trials Organisation and Eurofever Project
Published: May 2016

Objective

Mevalonate kinase deficiency (MKD) is a rare metabolic disease characterized by recurrent inflammatory episodes. This study was undertaken to describe the genotype, phenotype, and response to treatment in an international cohort of MKD patients.

Methods

All MKD cases were extracted from the Eurofever registry (Executive Agency for Health and Consumers project no. 2007332), an international, multicenter registry that retrospectively collects data on children and adults with autoinflammatory diseases.

Results

The study included 114 MKD patients. The median age at onset was 0.5 years. Patients had on average 12 episodes per year. Most patients had gastrointestinal symptoms (n = 112), mucocutaneous involvement (n = 99), lymphadenopathy (n = 102), or musculoskeletal symptoms (n = 89). Neurologic symptoms included headache (n = 43), cerebellar syndrome (n = 2), and mental retardation (n = 4). AA amyloidosis was noted in 5 patients, almost twice as many as expected from findings in previous cohorts. Macrophage activation syndrome occurred in 1 patient. Patients were generally well between attacks, but 10–20% of the patients had constitutional symptoms, such as fatigue, between fever episodes. Patients with p.V377I/p.I268T compound heterozygosity had AA amyloidosis significantly more often. Patients without a p.V377I mutation more often had severe musculoskeletal involvement. Treatment with nonsteroidal antiinflammatory drugs relieved symptoms. Steroids given during attacks, anakinra, and etanercept appeared to improve symptoms and could induce complete remission in patients with MKD.

Conclusion

We describe the clinical and genetic characteristics of 114 MKD patients, which is the largest cohort studied so far. The clinical manifestations confirm earlier reports. However, the prevalence of AA amyloidosis is far higher than expected.
Usual and stochastic tail orders between hitting times for two Markov chains
Authors: De Santis Emilio , Spizzichino Fabio
Published: May 2016

We consider time‐homogeneous Markov chains with state space Ek≡{0,1,…,k} and initial distribution concentrated on the state 0. For pairs of such Markov chains, we study the Stochastic Tail Order and the stochastic order in the usual sense between the respective first passage times in the state k. On this purpose, we will develop a method based on a specific relation between two stochastic matrices on the state space Ek. Our method provides comparisons that are simpler and more refined than those obtained by the analysis based on the spectral gaps. Copyright © 2016 John Wiley & Sons, Ltd.
Consensus coordinates from qualitative and quantitative attributes
Authors: Lefkovitch L. P.
Published: May 2016

By considering that each attribute of objects provides a coordinate system for them (in discrete space for qualitative or for ordered discrete quantitative attributes, in continuous space for continuous attributes), a compromise set of coordinates are derived. These coordinates differ from principal coordinates. Two small numerical examples illustrate the algebra.
The latent class analysis of polychotomous data
Authors: Formann Anton K.
Published: May 2016

The present paper deals with the polychotomous generalization of Lazarsfeld's latent class analysis. First of alla short description of the model is given. To avoid the well‐known problem of uninterpretable latent probabilities, a logistic transformation of the original parameters is proposed. In the following, the estimation equations for the auxiliary parameters are derived according to the maximum likelihood principle. The uniqueness of the solution is proven by investigating the matrix of second order partial derivatives of the log‐likelihood function.

Furthermore, statistical tests for the goodness of fit are described and the practical application and interpretation of the results are discussed. The formal presentation ends with an empirical example.
Luminescence enhancement of (Sr1–xMx)2SiO4:Eu2+ phosphors with M (Ca2+/Zn2+) partial substitution for white light‐emitting diodes
Authors: Wang Yulong , Zhang Wentao , Gao Yang , Long Jianping , Li Junfeng
Published: May 2016

Eu2+‐doped Sr2SiO4 phosphor with Ca2+/Zn2+ substitution, (Sr1–xMx)2SiO4:Eu2+ (M = Ca, Zn), was prepared using a high‐temperature solid‐state reaction method. The structure and luminescence properties of Ca2+/Zn2+ partially substituted Sr2SiO4:Eu2+ phosphors were investigated in detail. With Ca2+ or Zn2+ added to the silicate host, the crystal phase could be transformed between the α‐form and the β‐form of the Sr2SiO4 structure. Under UV excitation at 367 nm, all samples exhibit a broad band emission from 420 to 680 nm due to the 4f65d1 → 4f7 transition of Eu2+ ions. The broad emission band consists of two peaks at 482 and 547 nm, which correspond to Eu2+ ions occupying the ten‐fold oxygen‐coordinated Sr.(I) site and the nine‐fold oxygen‐coordinated Sr.(II) site, respectively. The luminescence properties, including the intensity and lifetime of Sr2SiO4:Eu2+ phosphors, improved remarkably on Ca2+/Zn2+ addition, and promote its application in white light‐emitting diodes. Copyright © 2016 John Wiley & Sons, Ltd.
Real‐time monitoring of specific oxygen uptake rates of embryonic stem cells in a microfluidic cell culture device
Authors: Super Alexandre , Jaccard Nicolas , Marques Marco Paulo Cardoso , Macown Rhys Jarred , Griffin Lewis Donald , Veraitch Farlan Singh , Szita Nicolas
Published: May 2016

Oxygen plays a key role in stem cell biology as a signaling molecule and as an indicator of cell energy metabolism. Quantification of cellular oxygen kinetics, i.e. the determination of specific oxygen uptake rates (sOURs), is routinely used to understand metabolic shifts. However current methods to determine sOUR in adherent cell cultures rely on cell sampling, which impacts on cellular phenotype. We present real‐time monitoring of cell growth from phase contrast microscopy images, and of respiration using optical sensors for dissolved oxygen. Time‐course data for bulk and peri‐cellular oxygen concentrations obtained for Chinese hamster ovary (CHO) and mouse embryonic stem cell (mESCs) cultures successfully demonstrated this non‐invasive and label‐free approach. Additionally, we confirmed non‐invasive detection of cellular responses to rapidly changing culture conditions by exposing the cells to mitochondrial inhibiting and uncoupling agents. For the CHO and mESCs, sOUR values between 8 and 60 amol cell−1 s−1, and 5 and 35 amol cell−1 s−1 were obtained, respectively. These values compare favorably with literature data. The capability to monitor oxygen tensions, cell growth, and sOUR, of adherent stem cell cultures, non‐invasively and in real time, will be of significant benefit for future studies in stem cell biology and stem cell‐based therapies.
Quantitative definition and monitoring of the host cell protein proteome using iTRAQ – a study of an industrial mAb producing CHO‐S cell line
Authors: Chiverton Lesley M. , Evans Caroline , Pandhal Jagroop , Landels Andrew R. , Rees Byron J. , Levison Peter R. , Wright Phillip C. , Smales C. Mark
Published: May 2016

There are few studies defining CHO host cell proteins (HCPs) and the flux of these throughout a downstream purification process. Here we have applied quantitative iTRAQ proteomics to follow the HCP profile of an antibody (mAb) producing CHO‐S cell line throughout a standard downstream purification procedure consisting of a Protein A, cation and anion exchange process. We used both 6 sample iTRAQ experiment to analyze technical replicates of three samples, which were culture harvest (HCCF), Protein A flow through and Protein A eluate and an 8 sample format to analyze technical replicates of four sample types; HCCF compared to Protein A eluate and subsequent cation and anion exchange purification. In the 6 sample iTRAQ experiment, 8781 spectra were confidently matched to peptides from 819 proteins (including the mAb chains). Across both the 6 and 8 sample experiments 936 proteins were identified. In the 8 sample comparison, 4187 spectra were confidently matched to peptides from 219 proteins. We then used the iTRAQ data to enable estimation of the relative change of individual proteins across the purification steps. These data provide the basis for application of iTRAQ for process development based upon knowledge of critical HCPs.
B7H6‐derived peptides trigger TNF‐α‐dependent immunostimulatory activity of lymphocytic NK92‐MI cells
Authors: Phillips Mariana , Romeo Francesca , Bitsaktsis Constantine , Sabatino David
Published: May 2016

The rise of biologics that can stimulate immune responses towards the eradication of tumors has led to the evolution of cancer‐based immunotherapy. Representatively, B7H6 has been recently identified as a protein ligand on tumor cells that binds specifically to the NKp30 receptor and triggers NK cell‐derived cytokine production, which ultimately leads to tumor cell lysis and death. In an effort to develop effective immunotherapy approaches, the rational design of a novel class of immunostimulatory peptides (IPs) derived from the binding interface of B7H6:NKp30 is described in this study. The IPs comprised the B7H6 active site sequence for NKp30 binding and immunostimulatory activity. An aminohexanoic acid linker was also introduced at the N‐terminus of the peptides for FITC‐labeling by Fmoc‐solid phase peptide synthesis. The peptides were characterized by LCMS to confirm identities and purities >95%. The secondary structures of the peptides were examined by CD spectroscopy in H2O, PBS and a H2O:TFE mixture which demonstrated versatile peptide structures which transitioned from random coil (H2O) to α‐helical (PBS) and turn‐type (H2O:TFE) conformations. Their biological properties were then evaluated by flow cytometry, enzyme‐linked immunosorbent assays (ELISAs), and cell death assays. The occupancy of the synthetic peptides to a human NK cell line demonstrated comparable binding relative to the natural NKp30 ligand, B7H6, and the human anti‐NKp30 monoclonal antibody (mAb), in a concentration dependent manner. A competitive binding assay between the human anti‐NKp30 mAb or B7H6, and the synthetic peptides, demonstrated partial displacement of the ligands upon anti‐NKp30 mAb treatment, suggesting NKp30 receptor specificities by the synthetic peptides. Moreover, the immunostimulatory activity of B7H6 was demonstrated by the secretion of the pro‐inflammatory cytokines tumor necrosis factor‐alfa (TNF‐α) and interferon gamma (IFN‐γ) by the human NK cell line. The immunostimulatory effects of IPs on the NK cells was assessed by the production of TNF‐α alone as IFN‐γ was undetectable. In a cell death assay, the IPs were found to be nontoxic, without any observable evidence of early or late stage apoptosis within the NK92‐MI cells. Taking these findings together, this novel class of synthetic peptides may prove to be a promising lead in the development of a peptide‐based immunotherapy approach, especially against B7H6 expressing tumors. © 2016 Wiley Periodicals, Inc. Biopolymers (Pept Sci) 106: 658–672, 2016.
Evaluation of Polyethersulfone‐based Composite for Selective Separation of Cesium from Acidic Media
Authors: Park Jai Il , Kim Jung Suk , Kim Young Bok , Kwon Hye Jung , Park Yong Joon
Published: May 2016

This article describes the performance of inorganic–organic ion exchanger for the separation of cesium ion from acidic media. The composite consisted of ammonium molybdophosphate and polyethersulfone as a functional adsorbent and a polymeric support, respectively. The physicochemical properties of the polymer composite were examined using different techniques including thermogravimetric analysis, scanning electron/optical microscopy, and infrared spectrometry. Cesium sorption capacity of the composite was evaluated through batch studies under various conditions. The dynamic sorption and recovery were also studied by performing column experiments. In addition, we demonstrated the possible use of the synthesized granule for the selective recovery of radioactive cesium in a post‐irradiated nuclear material solution containing multiple fission products.
Intramuscular nerve distribution of the hamstring muscles: Application to treating spasticity
Authors: Rha Dong‐Wook , Yi Kyu‐Ho , Park Eun Sook , Park Chunung , Kim Hee‐Jin
Published: May 2016

The aim of this article is to elucidate the ideal sites for botulinum toxin injection by examining the intramuscular nerve distributions in the hamstring muscles. The hamstring muscles, biceps femoris, semitendinosus, and semimembranosus (10 specimens each) were stained by the modified Sihler method. The locations of the muscle origins, nerve entry points, and intramuscular arborized areas were recorded as percentages of the total distance from the line crossing the medial and lateral tibial condyles (0%) to the ischial tuberosity (100%). Intramuscular arborization patterns were observed at 15–30% and 50–60% for the biceps femoris, 25–40% and 60–80% for the semitendinosus, and 20–40% for the semimembranosus. This study suggests that botulinum toxin injection for spasticity of the hamstring muscles should be targeted to specific areas. These areas, where the arborization of intramuscular nerve branches is maximal, are recommended as the most effective and safest points for injection. Clin. Anat. 29:746–751, 2016. © 2016 Wiley Periodicals, Inc.
Efficient Synthesis of Topologically Linked Three‐Ring DNA Catenanes
Authors: Li Qi , Wu Guangqi , Wu Wei , Liang Xingguo
Published: May 2016

Topologically controlled DNA catenanes are promising elements for the construction of molecular machines but present a significant effort in DNA nanotechnology. We report an efficient approach for preparing linear three‐ring catenanes (L3C) composed of single‐stranded DNA. The linking number was strictly controlled by using short complementary regions (6 nt) between each two DNA rings. High efficiency of forming three‐ring catenanes (yield as high as 63 %) was obtained by using an 80 nt oligonucleotide as the scaffold to draw close the three pre‐rings for hybridization between short complementary DNA. After assembly, three pre‐rings were closed by DNA ligation using three 12 nt oligonucleotides as splints to form interlocked three‐ring catenanes. L3C nanostructures were imaged in air by AFM: the catenane exhibited a smooth circular shape and was arranged in a line with well‐defined structure, as expected.
Prognostic Importance of Diastolic Dysfunction in Relation to Post Procedural Aortic Insufficiency in Patients Undergoing Transcatheter Aortic Valve Replacement
Authors: Kampaktsis Polydoros N. , Bang Casper N. , Chiu Wong S. , Skubas Nikolaos J. , Singh Harsimran , Voudris Konstantinos , Baduashvili Amiran , Pastella Kalliopi , Swaminathan Rajesh V. , Kaple Ryan K. , Minutello Robert M. , Feldman Dmitriy N. , Kim Luke , Hriljac Ingrid , Lin Fay , Bergman Geoffrey S. , Salemi Arash , Devereux Richard B.
Published: May 2016

Objectives

We sought to examine whether baseline diastolic dysfunction (DD) is associated with increased mortality in patients who develop aortic insufficiency (AI) after transcatheter aortic valve replacement (TAVR). Background: Significant post‐TAVR AI is associated with increased mortality, likely secondary to adverse hemodynamics secondary to volume overload and decreased LV compliance from chronic pressure overload. However, the effect of baseline DD on outcomes of patients with post‐TAVR AI has not been studied. Methods: A total of 195 patients undergoing TAVR were included in the study. Patients with moderate‐to‐severe mitral stenosis, prior mitral valve replacement or atrial fibrillation were excluded. DD was classified at baseline by a 2‐step approach as recommended by the American Society of Echocardiography while AI was evaluated 30 days post‐TAVR. Follow up data up to 2 years post‐TAVR was used in survival analysis. Results: Patients with severe baseline DD who developed ≥mild post‐TAVR AI had increased mortality compared to all other patients (HR = 3.89, CI: 1.76–8.6, P = 0.001), which remained significant after adjusting for post‐TAVR AI, pre‐TAVR AI, baseline mitral regurgitation, ejection fraction, pulmonary artery pressure, creatinine clearance and history of stroke. Conclusions: Even mild post‐TAVR AI may have a negative impact on outcomes of patients with underlying severe DD. © 2016 Wiley Periodicals, Inc.
The effect of two different renal denervation strategies on blood pressure in resistant hypertension: Comparison of full‐length versus proximal renal artery ablation
Authors: Chen Weijie , Ling Zhiyu , Du Huaan , Song Wenxin , Xu Yanping , Liu Zengzhang , Su Li , Xiao Peilin , Yuan Yuelong , Lu Jiayi , Zhang Jianhong , Li Zhifeng , Shao Jiang , Zhong Bin , Zhou Bei , Woo Kamsang , Yin Yuehui
Published: May 2016

Background

Renal denervation (RDN) is used to manage blood pressure (BP) in patients with resistant hypertension (rHT), but effectiveness is still a concern, and key arterial portion for successful RDN is not clear.

Objective

The aim of this study was to investigate the efficacy and safety of proximal versus full‐length renal artery ablation in patients with resistant hypertension (rHT).

Methods

Forty‐seven patients with rHT were randomly assigned to receive full‐length ablation (n = 23) or proximal ablation (n = 24) of the renal arteries. All lesions were treated with radiofrequency energy via a saline‐irrigated catheter. Office BP was measured during 12 months of follow‐up and ambulatory BP at baseline and 6 months (n = 15 in each group).

Results

Compared with full‐length ablation, proximal ablation reduced the number of ablation points in both the right (6.1 ± 0.7 vs. 3.3 ± 0.6, P < 0.001) and the left renal arteries (6.2 ± 0.7 vs. 3.3 ± 0.8, P < 0.001), with significantly shorter RF delivery time (P < 0.001), but higher RF power (P = 0.011). Baseline office BPs was 179.4 ± 13.7/102.8 ± 9.4 mm Hg in the full‐length group and 181.9 ± 12.8/103.5 ± 8.9 mm Hg in the proximal group (P > 0.5). Similar office BPs was reduced by −39.4 ± 11.5/−20.9 ± 7.1 mm Hg at 6 months and −38.2 ± 10.3/−21.5 ± 5.8 mm Hg at 12 months in the full‐length group (P < 0.001), −42.0 ± 11.6/−21.4 ± 7.9 mm Hg at 6 months and −40.9 ± 10.3/−22.1 ± 5.6 mm Hg at 12 months in the proximal group (P < 0.001), and progressive BP reductions were observed over the 6 months (P < 0.001) in both groups. The drop in ambulatory 24‐hr SBP and DBP were significantly less than the drop in office BP (P < 0.001). No renovascular or other adverse complications were observed.

Conclusions

The results indicate that proximal RDN has a similar efficacy and safety profile compared with full‐length RDN, and propose the proximal artery as the key portion for RDN. © 2016 Wiley Periodicals, Inc.
Understanding Palladium Acetate from a User Perspective
Authors: Carole William A. , Colacot Thomas J.
Published: May 2016

Invited for the cover of this issue is the group of Thomas J. Colacot at Johnson Matthey. The image depicts palladium acetate as a card trick that still needs to be practiced. Read the full text of the article at 10.1002/chem.201601450.
ChemInform Abstract: Photolysis of Water with Zn1‐xNixMn2O4 Powdered Spinel Oxides.
Authors: GAUTIER J. L. , BRENET J. , FUENTEALBA R.
Published: May 2016

It is shown that the H2 evolution efficiency, measured as a function of composition of the spinel, passes through a maximum at x = 0.75, which corresponds to an optimal Mn4+/Mn3+ ratio in octahedral sites.
ChemInform Abstract: Preparation, Structure, and Properties of 3H‐Cyclonona(def)biphenylen‐ 3‐one, a Potentially Antiaromatic Annulenone.
Authors: WILCOX C. F. JUN. , BLAIN D. A. , CLARDY J. , XU C.‐F.
Published: May 2016

Swern oxidation of the alcohol (I) yields the title compound (II) which gives the methylated product (IV) upon reaction with methylmagnesium chloride (III).
ChemInform Abstract: The anti‐Perovskite‐Like Crystal Structure of Tris(tetraaquocopper(II))‐bis(hexafluorometallates(III)), Cu3M2F12·12 H2O (M: V, Cr, Fe).
Authors: KUMMER S. , BABEL D.
Published: May 2016

The isostructural title compounds, obtained from the binary fluorides by hydrothermal synthesis, crystallize in the triclinic system, space group P1, Z=1.
ChemInform Abstract: Characterization of YBa2(Cu,Ag)3O7 Superconductors.
Authors: CAHEN D. , SCHWARTZ M. , REICH S. , FELNER I.
Published: May 2016

It is demonstrated that up to 1.5 at.% of Ag can be substituted for Cu in the superconductor YBa2Cu3O7‐x.
ChemInform Abstract: The Anodic Dissolution of Copper in Aqueous Acidic Solutions Containing F‐ Ions
Authors: POTVIN E. , DROGOWSKA M. , MENARD H. , BROSSARD L.
Published: May 2016

(pH 1.6‐6, 0.1 M KF) has been investigated by cyclic voltammetry and by some surface sensitive techniques (SEM, XPS, AES).
ChemInform Abstract: Regioselectivity in Dipolar Cycloaddition Reactions of N‐Phenylcinnamonitrilimine.
Authors: HASSANEEN H. M. , FARAG A. M. , SHAWALI A. S. , ALGHARIB M. S.
Published: May 2016

The hydrazide (I) is chlorinated to give the hydrazidoyl chloride (II) which reacts with the nucleophilic agents (IIIa) and (IIIb) to yield the compounds (IVa) and (IVb).
ChemInform Abstract: A Base‐Stabilized Terminal Phosphinidene Complex.
Authors: COWLEY A. H. , GEERTS R. L. , NUNN C. M.
Published: May 2016

Tris(pyrazolyl)borato ligands are suitable for stabilizing terminal phosphinidenes due to the chelate effect.
ChemInform Abstract: The Factors Stabilizing Square‐Planar Geometries in σ‐Bonding Amine Adducts: Crystal and Molecular Structure of Bis(N‐tosyl‐β‐alaninato)bis(piperidine)copper(II).
Authors: MENABUE L. , SALADINI M. , BATTAGLIA L. P. , BONAMARTINI CORRADI A.
Published: May 2016

By adding piperidine to a methanolic solution of bis(N‐tosyl‐β‐alaninato)copper(II) the violet, air‐stable, crystalline title complex (I) is obtained.
ChemInform Abstract: Chemistry of Enol Ethers. Part 78. Condensation of Malonic Aldehyde Tetraethyl Acetal with β‐Substituted Enol Alkyl Ethers.
Authors: MAKIN S. M. , KRUGLIKOVA R. I. , KHARITONOVA O. V. , ARSHAVA B. M.
Published: May 2016

The reaction between malonic aldehyde tetraethyl acetal (I) and the ethoxyvinyl compounds (II) (with an electron‐withdrawing substituent) affords the acetals (III) of 1,5‐dialdehydes, whereas diethoxyethene (IV) (with strong electron donors), on reaction with (I) yields the acetals (V) of 1,7‐dialdehydes.
ChemInform Abstract: Synthesis of (1)Benzothienonaphthyridines.
Authors: KUDO H. , TAKAHASHI K. , CASTLE R. C. , LEE M. L.
Published: May 2016

3‐Chloro‐2‐(chlorocarbonyl)benzothiophene (Ia) reacts with the o‐aminopyridine (II) to give the amide (Ib) which is photolytically cyclized to yield the lactam (III).
ChemInform Abstract: Synthesis of Aminomethyl and Amino Analogs of 5‐Benzylacyclouridine and 5‐Benzyloxybenzylacyclouridine.
Authors: CHU S. H. , CHEN Z. H. , WENG Z. Y. , ROWE E. C. , CHU E. , CHU M. Y. W.
Published: May 2016

The N‐hydroxyalkyl phthalimides (I) are converted to the chloromethyl ethers (III).
ChemInform Abstract: Studies on Diazepines. Part 25. Syntheses of Fully Unsaturated 1,4‐Oxazepines and 1H‐1,4‐Diazepines Using Photochemical Valence Isomerization of Tricycloheptene Systems.
Authors: KURITA J. , IWATA K. , TSUCHIYA T.
Published: May 2016

The tricyclic amines (II) are prepared by hydrogenolysis of the N‐benzyloxycarbonyl derivatives (I).
ChemInform Abstract: Reductive Cleavage of the O‐C(8) Bond in 5′‐O,8‐Cycloadenosines. Intramolecular Protection of the 8‐Position and the 5′‐Hydroxy Group in Adenosines.
Authors: SAKO M. , SAITO T. , KAMEYAMA K. , HIROTA K. , MAKI Y.
Published: May 2016

Selective cleavage of the N6‐acyl‐5'‐O,8‐cycloadenosines (I) is achieved by treatment with sodium cyanoborohydride, yielding the N6‐acyladenosines (II).
ChemInform Abstract: Holes in the Oxygen (2p) Valence Bands and the Concomitant Formation of Peroxide‐Like Species in Metal Oxides: Their Role in Metallicity and Superconductivity.
Authors: RAO C. N. R. , GANGULY P. , HEGDE M. S. , SARMA D. D.
Published: May 2016

In an effort to explore for the presence of O(2p) valence band holes forming peroxide‐like species, several oxide systems (BaO2, PbO, BaPbO3, SrPbO3, BaBiO3, BaBiPbO3, La2NiO4+δ) have been investigated by photoelectron spectroscopy.
ChemInform Abstract: A (1,2) and a (1,4) Shift in a Wittig Thioether Rearrangement. Isolation of a (1.1)(2,8)Naphthalenophane Tautomer.
Authors: GLEITER R. , SCHAAFF H. P. , HUBER‐PATZ U. , RODEWALD H. , GOETZMANN W. + , IRNGARTINGER H.
Published: May 2016

Treatment of the dithiacyclododecene (I) with butyllithium and methyl iodide (II) results in Wittig thioether rearrangement to give the isomeric sulfides (III) and (IV).
ChemInform Abstract: Structural Features and Crystallographic Examination of 5‐Acetyl‐ and 5‐Trifluoroacetyl‐2‐(N,N‐disubstituted amino)thiazoles.
Authors: CALDWELL J. M. , MEAKINS G. D. , JONES R. H. , KIDD T. R. , PROUT K.
Published: May 2016

The thiazoles (Id)‐(Ig) (yield 72‐77%) are prepared by acetylation according to (Ia) (yield given in g) whereas (Ic) (79%) is prepared from bromodione (IV) and N‐methyl‐N‐phenylthiourea according to (Ib) (yield given in g).
ChemInform Abstract: Electrochemical Cyclization of Unsaturated Hydroxy Compounds. Part 1. Phenylselenoetherification.
Authors: MIHAILOVIC M. LJ. , KONSTANTINOVIC S. , VUKICEVIC R.
Published: May 2016

Various hydroxyalkenes such as (I), (IV), (VI), and (IX) undergo electrochemical cyclization in the presence of diphenyl diselenide (II), yielding the phenylselenenyl(methyl)tetrahydrofurans (II), (V), (VII), or the corresponding tetrahydropyran derivatives (VIII) and (X).
ChemInform Abstract: Reactions of Tetra‐μ‐carboxylato‐diruthenium(II,II) Compounds. X‐Ray Crystal Structures of Ru2(μ‐O2CCF3)4(THF)2, Ru2(μ‐O2CR)4(NO)2 (R: Et or CF3), and (Na3(Ru2(μ‐O2CO)4)·6 H2O)n.
Authors: LINDSAY A. J. , WILKINSON G. , MOTEVALLI M. , HURSTHOUSE M. B.
Published: May 2016

Improved procedures for the synthesis of diruthenium(II) carboxylates (III) and their derivatives (X) and (XII) and substitutions of either the bridged carboxylate or axial ligands are reported.
ChemInform Abstract: The Solution Behavior of (Rh2(COMe)2(CO)2I6)2‐, Its Reactions with CO, Pyridine, and Methanol, and the X‐Ray Structure of (AsPh4) (Rh(COMe)(CO)(NC5H5)I3).
Authors: ADAMS H. , BAILEY N. A. , MANN B. E. , MANUEL C. P. , SPENCER C. M. , KENT A. G.
Published: May 2016

It is shown that the anion of (I) in CD2Cl2 consists of at least six species.
ChemInform Abstract: Structure of “Platinum Blue” Formed in the Reactions of the Isomeric Platinum(II) Dinitrodiammines with Phosphoric Acid.
Authors: KORSUNSKII V. I. , MURAVEISKAYA G. S. , ABASHKIN V. E.
Published: May 2016

The cis or the trans isomer of Pt(NH3)2(NO2)2 are heated in conc.
ChemInform Abstract: Efficient Methods for the Preparation of Acetylenic Ketones.
Authors: VERKRUIJSSE H. D. , HEUS‐KLOOS Y. A. , BRANDSMA L.
Published: May 2016

The acetylenic ketones (III) are prepared by treatment of the lithiated alkynes (I) with either acetic anhydride (II) or the carboxylic amides (IV).
ChemInform Abstract: 3‐Amino‐1H‐pyrazolo(5,4‐d)pyrimidines and 3‐Amino‐isothiazolo(5.4‐d)pyrimidines as Precursors of Tricyclic Heteroaromatic Systems Containing a Bridgehead Nitrogen Atom.
Authors: GOLEC J. M. C. , SCROWSTON R. M.
Published: May 2016

The reaction of the compounds (I) and (VI) with the ketones (II), (IV) and (VIII) yields the title heteroaromatic systems (III), (V), (VII) and (IX).
ChemInform Abstract: Characterization and Toxicity of Lanthanoid Complexes with Nitrogen‐ and Sulfur‐Containing Schiff Bases.
Authors: SIDDIQI K. S. , KURESHY R. I. , KHAN N. H. , TABASSUM S. , ZAIDI S. A. A.
Published: May 2016

The eight‐coordinate lanthanoid complexes (I) are prepared by 1:3 molar reaction of corresponding lanthanoid chlorides with the Schiff bases from sulfamethoxazole and salicylaldehyde or thiophene‐2‐aldehyde in ethanol.
ChemInform Abstract: Group IVA (C, Si, Ge, Sn, Pb) and Group VA (N, P, As, Sb, Bi) Elements
Authors: HARRISON P. G.
Published: May 2016

Review: (318 refs.
ChemInform Abstract: On the Importance of Charge Alternation
Authors: KLEIN J.
Published: May 2016

Review: (82 refs.
ChemInform Abstract: Dramatic Acceleration of the Diels‐Alder Reaction by Adsorption on Chromatography Adsorbents.
Authors: VESELOVSKY V. V. , GYBIN A. S. , LOZANOVA A. V. , MOISEENKOV A. M. , SMIT W. A. , CAPLE R.
Published: May 2016

The cycloadducts (III) and (V) are prepared by Diels‐Alder reaction of the α,β‐unsaturated carbonyl compounds (I) with cyclopentadiene (II) or from (Ia) or (Ic) and ethyl vinyl ether (IV), using dry state adsorption conditions.
ChemInform Abstract: Low Coordinated Phosphorus Compounds. Part 62. Valence Isomerization of λ3‐Monophosphahexadienes and λ3‐Monophosphahexenynes.
Authors: APPEL R. , KOCHTA J. , WINKHAUS V.
Published: May 2016

(3,3')‐Phospha‐carbon Cope rearrangements, hitherto known from tetraand diphosphahexadienes, are observed for the first time with monophosphahexadienes (III) and a monophosphahexenyne (VII).
ChemInform Abstract: Electrical Properties and Cation Valencies in Mn3O4.
Authors: DORRIS S. E. , MASON T. O.
Published: May 2016

Electrical conductivity of Mn3O4 is measured in the range 920‐1530 °C (tetragonal‐to‐cubic transformation at ≈ 1170 °C).
ChemInform Abstract: Photochemical Studies. Part 30. Unusual Photorearrangements of Homoconjugated Diacylcyclohexa‐2,4‐dienes.
Authors: OREN J. , SCHLEIFER L. , WEINMAN S. , FUCHS B.
Published: May 2016

Photolysis of the substituted dihydroindans (II), synthesized from the carboxylic anhydride (I), results in rearrangement processes, yielding the tricyclononene (III), or the all‐cis‐cyclononatrienes (IV) and (V).
ChemInform Abstract: Reactions of Imidazole‐2‐thiones with Molecular Iodine and the Structures of Two Crystalline Modifications of the 1:1 1,3‐Dimethylimidazole‐2‐thione‐Diiodine Charge‐Transfer Complex (C5H8I2N2S).
Authors: FREEMAN F. , ZILLER J. W. , PO H. N. , KEINDL M. C.
Published: May 2016

Imidazole‐2‐thione, 1‐methyl‐, and 1,3‐dimethylimidazole‐2‐thione (I) react with I2 to give 1:1 CT complexes (UV/VIS).
ChemInform Abstract: Pentacoordinated Molecules. Part 73. Square‐Pyramidal and Trigonal‐Bipyramidal Anionic (Ethanedithiolato)stannates. Binuclear Centers with Tin‐Sulfur Bonding.
Authors: HOLMES R. R. , SHAFIEEZAD S. , HOLMES J. M. , DAY R. O.
Published: May 2016

The first anionic five‐coordinate Sn compounds (I), (II), and (V) are formed from the reaction of alkyl‐ or aryltin trichlorides and tetraethylammonium chloride in acetone with sodium ethane‐1,2‐dithiolate (generated in methanol) and from partial hydrolysis of bis(ethane‐1,2‐dithiolato)‐Sn (III) in the presence of the amine bases L (IV).
ChemInform Abstract: Spectroelectrochemical Studies of High‐Valent Nitridomanganese Porphyrins.
Authors: BOTTOMLEY L. A. , NEELY F. L. , GORCE J.‐N.
Published: May 2016

Axial coordination of manganese porphyrins by the nitride ligand deactivates an otherwise electroactive central metal.
ChemInform Abstract: Production of Ultrafine Gold and Silver Particles by Means of a Gas Evaporation and Solvent Trap Technique.
Authors: SAITO Y. , NAKAHARA S. , TEO B. K.
Published: May 2016

Ultrafine colloidal Au and Ag particles suspended in ethanol are obtained by the title method.
ChemInform Abstract: Structure and Reactivity of Stannylated Propylamines and Propyl Sulfides. Crystal and Molecular Structure of Bis(3‐chlorodimethylstannylpropyl)sulfide S(CH2CH2CH2SnMe2Cl)2.
Authors: JURKSCHAT K. , SCHMID B. , DYBIONA M. , BAUMEISTER U. , HARTUNG H. , TZSCHACH A.
Published: May 2016

The reactions of the stannylated propylamines (IIIa), (IIIb) and the propyl sulfide (IIIc) with 2 equiv. dichlorodimethylstannane (V) lead to the azastannacycloalkanes (IV), (VI) and to the binuclear product (VII) (space group Pna21, Z=4), respectively.
ChemInform Abstract: Formation and the Magnetic Properties of the Compound Nd2Fe14C.
Authors: BUSCHOW K. H. J. , DE MOOIJ D. B. , DENISSEN C. J. M.
Published: May 2016

The title compound is prepared by arc melting of the elements and subsequent annealing of the as‐cast alloy in a narrow temp. range below 890 °C (∼ 830‐880 °C).
ChemInform Abstract: Reactivity of Monothio‐ and Monoselenoacetals Towards Oxidation in the Synthesis of Substituted 2,3‐Dihydrofurans.
Authors: BRUNETIERE A. P. , LALLEMAND J.‐Y.
Published: May 2016

The butyrolactone (I) is reduced with diisobutylaluminum hydride and then treated with thio‐ or selenophenol (II) to give the substitution products (III).
ChemInform Abstract: 9,10‐Dicyanoanthracene‐Sensitized NO Insertion into the Cyclopropane Ring via Photoinduced Electron Transfer.
Authors: ICHINOSE N. , MIZUNO K. , YOSHIDA K. , OTSUJI Y.
Published: May 2016

1,2‐Diarylcyclopropanes such as (Ia), (Ib), (Id), and (Ie) with electron donating aryl substituents undergo sensitized photoreaction with NO (II) in the presence of 9,10‐dicyanoanthracene to form the 2‐isoxazolines (III).
ChemInform Abstract: Studies in Medicinal Plants. Part 16. New Xanthone from Hypericum mysorense Heyne.
Authors: BALACHANDRAN S. , VISHWAKARMA R. A. , POPLI S. P. , KAPIL R. S.
Published: May 2016

The xanthone (III) is isolated together with seven known xanthones from the antifungal fraction of the title species.
ChemInform Abstract: The Substituent Effect on the Reactivity of Silanes Toward tert‐Butoxyl Radicals.
Authors: CHATGILIALOGLU C. , ROSSINI S.
Published: May 2016

The absolute rate constant for the reaction of tert. butoxyl radicals with tris(trimethylsilyl)silane is measured by laser flash photolysis.
ChemInform Abstract: Removal of N‐Arylsulfonyl Groups from Hydroxy α‐Amino Acids.
Authors: ROEMMELE R. C. , RAPOPORT H.
Published: May 2016

In order to convert the N‐(arylsulfonyl)threonines (I) into threonine (II), three specific reductive methods are compared, namely, sodium in liquid ammonia, HBr in acetic acid, and electrolysis.
ChemInform Abstract: Synthesis of Pyrido‐1,3‐thiazines.
Authors: DUNN A. D. , NORRIE R.
Published: May 2016

In connection with the search for pharmaceutically interesting fused pyridines, a series of title compounds is prepared.
ChemInform Abstract: Synthesis of (S)‐(+)‐Cryptone.
Authors: MANCINI I. , GUELLA G. , PIETRA F.
Published: May 2016

The title compound (VII) can be prepared from commercially available (R)‐(+)‐p‐menthene (I) with 27% overall yield and ca. 70% e.e.
ChemInform Abstract: Spectroscopic (IR, UV‐VIS, 1H and 119Sn NMR, Resonance Raman) Properties of ((C6H5)3EM(CO)3(α‐diimine)) (M: Mn, E: Ge, Sn, Pb; M: Re, E: Sn) Complexes and X‐Ray Structure of ((C6H5)3SnMn(CO)3(tBu‐DAB)).
Authors: ANDREA R. R. , DE LANGE W. G. J. , STUFKENS D. J. , OSKAM A.
Published: May 2016

In order to get more insight into the electronic structures of the complexes (I) their spectroscopic properties are discussed and a comparison is made with the parent compounds Ph3EM(CO)5 for which a qualitative MO diagram is given.
ChemInform Abstract: First Experimental Evaluation of Hypervalent N‐S‐N Bond Energy from the Restricted Rotation of Pyrimidine Ring in 10‐S‐3 Sulfuranes (I).
Authors: AKIBA K. , OHSUGI M. , IWASAKI H. , OHKATA K.
Published: May 2016

1H NMR line‐shape analysis of the methyl signals in (Ia) (coalesces at 45 °C; heteroaromatic peaks remain unchanged between 28‐58 °C) affords k = 8.6 s‐1and ΔG‡ = 16.6.
ChemInform Abstract: Synthesis and Biological Activity of 5(6)‐Amido‐ and 5(6)‐Amino‐2‐arylbenzimidazole Derivatives.
Authors: SKLYAROVA I. V. , KUZNETSOV V. A. , SOKOLOVA N. YU. , GARABADZHIU A. V. , GINZBURG O. F. , DOBRYNIN YA. V. , NIKOLAEVA T. G. , FIN'KO V. E.
Published: May 2016

o‐Diaminobenzenes, prepared in situ from the corresponding nitroalinines (I), are coupled with the carboximidate (II) to give the benzimidazoles (III).
ChemInform Abstract: Simple Phenylnitrones and Their Transformation into Substituted Isoxazolidines.
Authors: ZELENIN K. N. , BEZHAN I. P. , ERSHOV A. YU.
Published: May 2016

The carbonyl compounds (I) react with phenylhydroxylamine (II) to give the nitrones (III) which dimerize upon standing, producing the isoxazolidines (IV).
ChemInform Abstract: Insertion of Carbon Dioxide into a Molybdenum‐Hydrogen Bond. Photochemical Formation of Hydridoformato Complex of Molybdenum(II).
Authors: ITO T. , MATSUBARA T.
Published: May 2016

(III) is air‐stable as a solid but decomposes readily in solution.
ChemInform Abstract: Di‐ and Trinuclear Complexes of Palladium(II) Containing Doubly‐ and Triply‐Bridging Pyridine‐2‐thionato (pyS) Ligands: Crystal Structure of (Pd3(C6H4CH2NMe2)3(pyS)2) (BF4).
Authors: DEEMING A. J. , MEAH M. N. , BATES P. A. , HURSTHOUSE M. B.
Published: May 2016

The chloride‐bridged Pd dimer (I) reacts with the 1H‐pyridine‐2‐thiones (II) as shown to generate the dinuclear complexes (III).
ChemInform Abstract: A Simple, High‐Yield Synthesis of Tetraphosphorus Triselenide, P4Se3.
Authors: STOPPIONI P. , PERUZZINI M.
Published: May 2016

The title cluster compound (III) is prepared by reaction of red phosphorus with steel‐grey selenium.
ChemInform Abstract: Enantioselective Ring Cleavage of meso‐Epoxides with B‐Halodiisopinocampheylboranes.
Authors: JOSHI N. N. , SREBNIK M. , BROWN H. C.
Published: May 2016

The enantioselective ring opening reaction of the meso‐epoxides (I), (III), (VI), (VIII) using the B‐iododiisopinocampheylborane (V) leads to the optically active 1,2‐halohydrins (II), (IV), (VII), (IX).
ChemInform Abstract: Dicobalt Octacarbonyl Catalyzed Conversion of Benzylic Alcohols to Thiols, Hydrocarbons, and Esters Using Hydrogen Sulfide and Carbon Monoxide.
Authors: ALPER H. , SIBTAIN F.
Published: May 2016

The benzylic alcohols (I) react with hydrogen sulfide and carbon monoxide in the presence of dicobalt octacarbonyl to form the thiols (II) and the hydrocarbons (III) as the main products.
ChemInform Abstract: Regio‐ and Stereoselective C‐Alkylation of Enamines Derived from 2‐Methyl‐1,3‐cyclopentanedione in the Presence of Strong Bases.
Authors: LAKHVICH F. A. , LIS L. G. , PAP A. A.
Published: May 2016

The stereo‐ and regioselectivity of the alkylation of the enamine (III) derived from the cyclopentane dione (II) is investigated.
ChemInform Abstract: Conversion of 2‐Arylmethylene‐3‐indolinones to 4‐(2‐Acetylaminobenzoyl)‐5‐aryl‐1,2,3‐triazoles.
Authors: VELEZHEVA V. S. , MARSHAKOV V. YU. , MEL'MAN A. I. , KURKOVSKAYA L. N. , SUVOROV N. N.
Published: May 2016

Condensation of the indolinone (I) with the aromatic aldehydes (II) affords the 2‐arylidene derivatives (III).
ChemInform Abstract: The 5‐Hydroxy‐1,2,3‐oxadiazolinium Ion: Neighboring Group Interaction Between N‐Nitroso and Aldehyde Carbonyl.
Authors: LOEPPKY R. N. , FLEISCHMANN E. D. , ADAMS J. E. , TOMASIK W. , SCHLEMPER E. O. , WONG T. C.
Published: May 2016

A set of MNDO calculations performed on (I) and (II) to explore possible neighboring group interactions demonstrates the formation of the stable cation (III) from the protonated aldehyde (IIa).
ChemInform Abstract: Chemistry of Polynuclear Metal Complexes with Bridging Carbene or Carbyne Ligands. Part 79. Synthesis and Reactions of the Alkylidynemetal Complexes (M(CR)(CO)2(η‐C5H5)) (R: C6H3Me2‐2,6, M: Cr, Mo, or W; R: C6H4Me‐2, C6H4OMe‐2, or C6H4NMe2‐4, M: Mo); Crystal Structure of the Compound (MoFe(μ‐CC6H3Me2‐2,6)(CO)5(η‐C5H5)).
Authors: DOSSETT S. J. , HILL A. F. , JEFFERY J. C. , MARKEN F. , SHERWOOD P. , STONE F. G. A.
Published: May 2016

In order to define more precisely the effect of the aryl group in substituted methylidyne metal complexes of type (I), the compounds (Ia)‐(If) (where the predominantly used p‐tolyl substituent is replaced by electronically and sterically different aryl groups) are prepared in yields of 60‐80% by the extension of known procedures.
ChemInform Abstract: Preparation of an Oxoperoxocyanomolybdate(VI) Complex by Dioxygen Oxidation of an Oxocyanomolybdate(IV) Anion. Structure and Reactivity Toward Phosphines and Olefins.
Authors: ARZOUMANIAN H. , PETRIGNANI J.‐F. , PIERROT M. , RIDOUANE F. , SANCHEZ J.
Published: May 2016

The oxopentacyanomolybdate(IV) (III) is prepared by controlled hydrolysis of the octacyanomolybdate (I).
ChemInform Abstract: Bis((pentamethylcyclopentadienyl)metal)pentalenes. A New Class of Highly Delocalized, Fused Metallocenes.
Authors: BUNEL E. E. , VALLE L. , JONES N. L. , CARROLL P. J. , BARRA C. , GONZALEZ M. , MUNOZ N. , VISCONTI G. , AIZMAN A. , MANRIQUEZ J. M.
Published: May 2016

The air‐sensitive title compounds (IV) are prepared in a one‐pot procedure as outlined in the scheme.
ChemInform Abstract: Stereoselective Formation of a Steroidal 20‐Hydroxy‐24‐oic Lactone by a Novel Reaction of Dichloro Ketene with an Epoxy Olefin.
Authors: RAMESH U. , WARD D. , REUSCH W.
Published: May 2016

Reaction of the pregnene derivative (I) with dichloro ketene (II), generated in situ from the trichloroacetyl chloride and zinc dust, leads unexpectedly to the formation of the dichloro lactone (III) which is reduced to the monochloro derivative (IV).
ChemInform Abstract: 2‐Benzoyl‐4‐substituted‐phenyl‐5‐phenylthiazoles.
Authors: KULKARNI R. A. , THAKER S. R.
Published: May 2016

The α‐bromodeoxybenzoins (I) are cyclized with the thioamide (II) to give the thiazoles (III).
ChemInform Abstract: Reaction of Tosylamide Monosodium Salt with Bis(halomethyl) Compounds: An Easy Entry to Symmetrical N‐Tosyl Aza Macrocycles.
Authors: BOTTINO F. , DI GRAZIA M. , FINOCCHIARO P. , FRONCZEK F. R. , MAMO A. , PAPPALARDO S.
Published: May 2016

The 1,ω‐dihalooxaalkanes (I) react with the tosylamide monosodium salt (II) in DMF to give the cyclic products (III).
ChemInform Abstract: Nitrogen Atom Activation: The Influence of Porphyrin Ring Structure on the Kinetics of the Reaction of Trifluoroacetic Anhydride with Nitrido Manganese(V) Porphyrins.
Authors: BOTTOMLEY L. A. , NEELY F. L.
Published: May 2016

The kinetics of the reactions of (I) (and 6 other phenyl‐substituted analogues), (II) and (III) with trifluoroacetic anhydride and of (II) with trifluoro‐, trichloro‐, dichloro‐, monochloro‐ and unsubstituted acetic anhyride to form the corresponding nitrenoid Mn porphyrin complex are determined under pseudo‐first‐order conditions.
ChemInform Abstract: 3‐ and 3,6‐Silylated 2‐Pyridinethiols: New Bulky Bidentate Ligands and Their Silver and Copper Clusters.
Authors: BLOCK E. , GERNON M. , KANG H. , ZUBIETA J.
Published: May 2016

The mono‐ and disilylated pyridinethiols (I) and (V) are prepared by the one‐pot reaction of pyridinethiol (III) with LDA and addition of the corresponding chlorosilanes (II) or (IV) depending on the silane substituents.
ChemInform Abstract: The Structure of PBr4Cl3
Authors: DILLON K. B. , NISBET M. P. , REEVE R. N.
Published: May 2016

is investigated by means of 31P NMR and Raman spectroscopy.
ChemInform Abstract: Friedel‐Crafts Alkylation of Pyrene in Carbon Disulfide; 1H NMR Spectroscopy of Pyrene Derivatives.
Authors: RODENBURG L. , DE BLOCK R. , ERKELENS C. , LUGTENBURG J. , CORNELISSE J.
Published: May 2016

Whereas 2,5‐dichloro‐ and 2,5‐diiodohexane lead to products not identified to be pyrene derivatives, compounds (I) yield cleanly (III).
ChemInform Abstract: Alkyl 2‐Methyldithiocarbazates in Heterocyclic Synthesis: Preparation of 2‐Alkylthio‐1,3,4‐thiadiazolium Cations and 2‐Thioxo‐2,3‐dihydro‐1,3,4‐oxadiazole Derivatives.
Authors: MOLINA P. , TARRAGA A. , ESPINOSA A.
Published: May 2016

Acylation of the 2‐methyldithiocarbazates (I) gives the 3‐acyl derivatives (III) which cyclize upon treatment with perchloric acid and acetic anhydride, forming the 1,3,4‐thiadiazolium salts (IV).
ChemInform Abstract: Preparation and Properties of Novel Sulfur Heterocycles from the Reaction of 4,5‐Disubstituted 2‐Lithio‐1,3‐dithioles with Carbon Disulfide and X‐Ray Crystallographic Structure of 2‐(4,5‐Dimethyl‐1,3‐dithiolylidene)‐5,6‐dimethyl‐2,3‐dihydro‐1,4‐dithiine‐3‐thione.
Authors: MORADPOUR A. , BITTNER S. , BERNSTEIN J. , SARMA J. A. R. P.
Published: May 2016

The reaction of the respective 2‐lithio derivatives from the dithioles (I) with CS2 (II) followed by treatment with ethyl chloroformate (or MeI) produces a new type (III) of heterocyclic system.
ChemInform Abstract: A Novel Asymmetric Synthesis of Substituted Cyclopropanes.
Authors: MEYERS A. I. , ROMINE J. L. , FLEMING S. A.
Published: May 2016

The chiral, nonracemic bicyclic lactams (I) are used to prepare the optically active cyclopropanes (V).
ChemInform Abstract: 2‐(2‐Aryl‐2‐oxoethylidene)‐1,2,3,4‐tetrahydropyridines. Novel Isomers of 1,4‐Dihydropyridine Calcium Channel Blockers.
Authors: TAYLOR M. D. , BADGER E. W. , STEFFEN R. P. , HALEEN S. J. , PUGSLEY T. A. , SHIH Y. H. , WEISHAAR R. E.
Published: May 2016

Tetrahydropyridine derivatives such as (IV), (VI), and (IX) are prepared using the Hantzsch dihydropyridine synthesis.
ChemInform Abstract: Synthesis and Characterization of New Adducts of Cobalt Bis(2,4‐pentanedionate). Molecular Structure of a Cis Complex: Cobalt Bis(2,4‐pentanedionate) N,N,N′,N′‐Tetraethyl‐1,2‐diaminoethane.
Authors: COLBORN R. E. , GARBAUSKAS M. F. , HEJNA C. I.
Published: May 2016

Bis(acetylacetonato)‐Co (I) reacts with a variety of bidentate ligands such as (II) to give nearly octahedral 1:1 adducts which are characterized spectroscopically.
ChemInform Abstract: Trimethylamine Oxide Induced Decarbonylation of M(CO)2Cl2(PPh3)2 (M: Ru, Os) Complexes.
Authors: FOLEY B. L. , SMITH C. A. , THOMAS N. C.
Published: May 2016

The title dicarbonyl complexes (I) are monodecarbonylated by 0.5 equiv. trimethylamine oxide in the presence of phenanthroline (II) to give the cationic complexes (III) isolated as their hexafluorophosphates.
ChemInform Abstract: Electron Spin Resonance and Electron Spin Echo Spectroscopic Studies of Cu2+ Sites in Synthetic Cancrinite Zeolites.
Authors: RAGHUNATHAN P. , KEVAN L.
Published: May 2016

Cu2+ is introduced (ion exchange) into the synthetic cancrinite zeolites Na6Al6Si6O24·8 H2O (I) and Na6Al6Si6O24·CaCO3·8 H2O (II).
ChemInform Abstract: Photochemistry of Cyclopropene Derivatives. Intramolecular Hydrogen Transfer Reaction of Some 1‐(Alkyl‐Substituted) Cyclopropenes.
Authors: PADWA A. , CHOU C. S. , ROSENTHAL R. J. , TERRY L. W.
Published: May 2016

The thioxanthone triplet‐sensitized photoirradiation of the cyclopropenes (I) or (III) gives either spirocyclopropanes such as (II) or cyclopropanes such as (IV) due to intramolecular hydrogen transfer.
ChemInform Abstract: Stereochemical Behavior of Intermediary Compounds in the Amine‐Catalyzed Knoevenagel Reaction.
Authors: TANIKAGA R. , KONYA N. , HAMAMURA K. , KAJI A.
Published: May 2016

Knoevenagel reaction of the methylene compounds (I) and the aldehydes (II) in the presence of a secondary amine produces the thermodynamically stable alkenes (III).
ChemInform Abstract: Synthesis of Diperoxy Ketals from 5,5,6‐Trimethylbicyclo(2.2.1)heptan‐2‐one.
Authors: YUVCHENKO A. P. , BERESNEVICH L. B. , ZHUKOVSKAYA N. A. , KOZLOV N. G. , MOISEICHUK K. L. , OL'DEKOP YU. A.
Published: May 2016

The novel title compounds (III), (V), (VI) and (VII) are prepared starting from the bicyclic ketone (I) specified in title and the corresponding peroxides.
ChemInform Abstract: New Synthetic Approaches to Cyclopenta(a)phenanthrenes and Their Carcinogenic Derivatives.
Authors: LEE H. , HARVEY R. G.
Published: May 2016

The naphthylalkyl iodides (I) are coupled with the bromomagnesium enamide (II), obtained from cyclopentenylcyclohexylamine and ethylmagnesium bromide, yielding the adducts (III).