bluuebunny/crossref_metadata_2025 huggingface dataset:
The Construct of Job Insecurity at Multiple Levels: Implications for Its Conceptualization and Theory Development
Authors: Sora Beatriz , Höge Thomas , Caballer Amparo , Peiró José Maria
Published: February 2023

Over the years, job insecurity has accumulated important scholarly work. As a result, research has identified multiple constructs that involve employees’ concerns about job loss. Most of these are individual-level constructs (e.g., subjective and objective job insecurity), but, recently, an incipient body of literature has adopted a multilevel perspective by understanding job insecurity as a collective phenomenon (e.g., job insecurity climate, strength climate, downsizing or temporary hiring strategies). Furthermore, these constructs at different levels are underpinned by shared theoretical frameworks, such as stress theory or psychological contract theory. However, all this literature fails to present an integrative framework that contains the functional relationship for mapping job insecurity constructs across levels. Accordingly, the present study aims to examine job insecurity from a multilevel perspective, specifically by conceptualizing job insecurity at the individual level—understood as subjective and objective job insecurity—and at the organizational level, understood as job instability in an organization, job insecurity climate, and climate strength. The methodology of multilevel construct validation proposed by Chen, Mathieu and Bliese (2005) was applied; thus, (1) job insecurity were defined at each relevant level of analysis; (2) its nature and structure was specified at higher levels of analysis; (3) psychometric properties were tested across and/or at different levels of analysis; (4) the extent to which job insecurity varies between levels of analysis was estimated; and (5) the function of job insecurity was tested across different levels of analysis. The results showed significant relationships among these, and were related to an organizational antecedent (e.g., organization nature) and organizational and individual outcomes (collective and individual job satisfaction) in two European samples: Austria and Spain. Accordingly, this study exposed the multilevel validity of job insecurity constructs through an integrative framework in order to advance in the area of job insecurity theory and practice. The contributions and implications to job insecurity research and other multilevel research are discussed.
Consumption of Sugary Drinks among Urban Adults in Colombia: Association with Sociodemographic Factors and Body Adiposity
Authors: Santana-Jiménez Maria A. , Nieves-Barreto Luz D. , Montaño-Rodríguez Angélica , Betancourt-Villamizar Carolina , Mendivil Carlos O.
Published: February 2023

Introduction: Calories from sugar-sweetened beverages (SSBs) contribute to the development of noncommunicable diseases. There is limited knowledge of the intake of SSBs and their correlates in developing countries. Thus, this study aimed to estimate the consumption of multiple SSBs and their sociodemographic correlates in an urban adult population from Colombia, South America. Methods: This was a probabilistic, population-level study of adults aged 18 to 75 from five cities representing different regions of Colombia. Dietary intake was assessed employing a 157-item semiquantitative food frequency questionnaire that inquired about intake over the last year. The consumption of regular soda, low-calorie soda, homemade and industrialized fruit juices, energy drinks, sport drinks, malt drinks and traditional sugar cane infusion (“agua de panela”) was analyzed for the total sample and subgroups defined by sociodemographic and clinical factors of interest. Results: The study included 1491 individuals (female: 54.2%, mean age: 45.3, overweight: 38.0%, obese: 23.3%). Sugary beverages contributed, on average, 287 Cal/d among women and 334 Cal/d among men, representing 8.9% of total daily calories (TDC). Women in the lowest SEL consumed 10.6% of their TDC from sugary drinks, as opposed to 6.6% for those in a high SEL. For men, this difference was not present (p-value for interaction = 0.039). Interestingly, a higher educational level correlated with a lower consumption of calories from sugary drinks only among men. Fruit juices were by far the main source of sugary drinks, and their consumption did not change sizably by sex and socioeconomic or educational level. Among women, there was a negative association between socioeconomic level (SEL) and consumption of regular soda, a 50% difference between extreme levels. The intake of low-calorie soda was much higher among men than women, and it more than tripled in the highest vs. lowest SEL among men. The consumption of energy drinks was heavily concentrated in men of low SEL. Conclusion: Colombian urban adults obtain a considerable proportion of their calories from sugary drinks, especially vulnerable groups such as women with lower education. Given the recent acceleration of the obesity epidemic in Latin America, strategies to limit the intake of such liquid calories may provide important public health benefits.
Social Support Networks and Care for People Who Use Harmful Drugs
Authors: Bortolai Letícia Andriolli , Malfitano Ana Paula Serrata
Published: February 2023

Background: The “problem of drugs” is a complex phenomenon with different social dimensions. Thus, the strategy to care for people who use drugs should consider their social support networks, which are defined here as dimensions that compose the social integration of people. Objective: In this paper, we investigate how social support networks are organized, structured, and constituted according to clients of a mental health service dedicated to treat alcohol and drug abuse. Methods: Participant observation was employed in a mental health service for three months, and six interviews and three groups of activities were conducted with local clients. Results: The results demonstrated that the social network of this group is composed of informal and formal social supports: the former includes family, religious institutions, and work, and the latter was represented by a few institutions. However, there are few supports that contribute to the social inclusion and participation of these clients. Conclusions: Care actions should expand social networks, helping to create more solid relationships, considering the macro and micro social-life dimensions. Occupational therapists can contribute to this process by driving their action toward social life, building more social participation strategies, and reconfiguring care and social meaning in everyday life.
Reduction of Hexavalent Chromium from Soil of the Relocated Factory Area with Rice Straw Hydrothermal Carbon Modified by Nano Zero-Valent Iron (nZVI)
Authors: Zhong Wei , Bai Weiyang , Li Gang
Published: February 2023

In order to reduce the content of Cr(VI) in the soil of the relocated chromium salt factory, the rice straw-derived hydrothermal carbon was prepared by hydrothermal method and loaded with nano zero-valent iron generated by liquid phase reduction, which effectively alleviated the self-aggregation problem of nano zero-valent iron (nZVI) in the treatment of Cr(VI) and improved the Cr(VI) reduction rate without changing the soil structure. The reduction effect of Cr(VI) in soil by key influencing factors such as carbon-iron ratio, initial pH value, and initial temperature was investigated. The results showed that nZVI modified hydro-thermal carbon composite (named RC-nZVI) had a good reduction effect on Cr(VI). Scanning electron microscope (SEM) and energy spectrum analysis showed that nZVI was evenly distributed on the surface of hydrothermal carbon, which effectively reduced the agglomeration of iron. Under the conditions of C/Fe = 1:2, 60 °C, with pH of 2, the average Cr(VI) content in soil decreased from 182.9 mg kg−1 to 21.6 mg kg−1. Adsorption kinetics of Cr(VI) by RC-nZVI fit well with the pseudo-second-order model, and the kinetic velocity constant revealed that Cr(VI) reduction rate decreased with increasing initial Cr(VI) concentration. Cr(VI) reduction by RC-nZVI was mainly dominated by chemical adsorption.
The Prevalence of Symptomatology and Risk Factors in Mental Health in Mexico: The 2016–17 ENCODAT Cohort
Authors: Medina-Mora María Elena , Genis-Mendoza Alma Delia , Villatoro Velázquez Jorge Ameth , Bustos-Gamiño Marycarmen , Bautista Clara Fleiz , Camarena Beatriz , Martínez-Magaña José Jaime , Nicolini Humberto
Published: February 2023

There is little recent information about the prevalence of symptomatology of mental health disorders in representative population samples in Mexico. To determine the prevalence of mental health symptoms in Mexico and its comorbidity with tobacco, alcohol, and drug use disorder (SUD), we used the 2016–17 National Survey of Drug, Alcohol, and Tobacco Use (Encuesta Nacional de Consumo de Drogas, Alcohol y Tabaco, ENCODAT 2016–2017). The data were collected from households using a cross-sectional, stratified, multistage design, with a confidence level of 90% and a response rate of 73.6%. The final sample included 56,877 completed interviews of individuals aged 12–65, with a subsample of 13,130 who answered the section on mental health. Symptoms of mania and hypomania (7.9%), depression (6.4%), and post-traumatic stress (5.7%) were the three main problems reported. Of this subsample, 56.7% reported using a legal or illegal drug without SUD, 5.4% reported SUD at one time on alcohol, 0.8% on tobacco, and 1.3% on medical or illegal drugs, 15.9% reported symptoms related to mental health, and 2.9% comorbidity. The prevalence found is consistent with those reported in previous studies, except for an increase in post-traumatic stress, which is consistent with the country’s increase in trauma.
Being a Parent of Children with Disabilities during the COVID-19 Pandemic: Multi-Method Study of Health, Social Life, and Occupational Situation
Authors: Fortin-Bédard Noémie , Ladry Naomie-Jade , Routhier François , Lettre Josiane , Bouchard David , Ouellet Béatrice , Grandisson Marie , Best Krista L. , Bussières Ève-Line , Baron Marie , LeBlanc Annie , Lamontagne Marie-Eve
Published: February 2023

Parents of children with disabilities face challenges in their daily lives, but little is known about their experience of the COVID-19 pandemic. The objective of the study was to explore the experiences of parents of children with disabilities during the COVID-19 pandemic in Quebec, Canada. Forty parents of children with disabilities from Quebec, Canada (mean [SD] age: 41.2 [6.7]; 93% women) were selected from the Ma Vie et la pandémie (MAVIPAN) study. All 40 parents completed the MAVIPAN online questionnaires including the Depression, Anxiety and Stress Scale (DASS-21), Warwick–Edinburgh Mental Wellbeing short 7-item scale (WEMWBS), Social Provisions Scale-10 item (SPS-10), and the UCLA Loneliness Scale (UCLA-LS). A multi-method analysis was used to summarize questionnaires and thematically explore parents’ experiences. Parents reported deterioration in their mental (50.0%) and physical (27.5%) health, with moderate levels of depression, stress, and anxiety, yet moderately positive well-being. Additional experiences included reduction in available supports (71.4%) and feelings of social isolation (51.4%). Our results highlighted reduced mental and physical health, limited and modified access to certain services, and reduction of social supports for some parents of children with disabilities. Health professionals, policymakers, and governments should be mindful of these challenges experienced by parents of children with disabilities.
High-Rise Residential Outdoor Space Value System: A Case Study of Yangtze River Delta Area
Authors: Yang Jing , Liu Yingzhu , Zhang Boyi
Published: February 2023

The outbreak of COVID-19 has drawn wider attention from residents with growing demand for outdoor space in residential areas because of restrictions on residents’ mobility, especially in China. However, the high-rise residential complex in China is featured with a high population density along with less outdoor space per household. This means that the current status of outdoor space in residential areas is far from satisfying residents’ growing needs. This is consistent with our preliminary survey that highlights general low satisfaction of residents with outdoor space. According to the hierarchical theory of needs, a literature review, and a questionnaire survey, a framework is proposed in this study to examine the universal value system of high-rise residential outdoor space using the Yangtze River Delta Area as a case study. This framework consists of six dimensions, i.e., space physical comfort (physical environment and space size), space function (functional complexity and scale, age-range, and time-range), space safety (daily, social, and hygiene safety), space diversity (spatial layerings, forms, and scales diversity), accessibility (spatial attraction and concentration and path clarity) and sustainability (cultural, social, ecological, and financial sustainability). Consequently, a questionnaire was designed according to the framework and 251 valid questionnaires were received. Then, structural equation modeling (SEM) was undertaken to examine the impact of each dimension on the value of outdoor space and the framework was optimized into four dimensions, i.e., space physical comfort, space function, space safety, and DAT (space diversity, accessibility, and sustainability). Finally, the mechanism of how outdoor space quality influences the high-rise residential complex is analyzed. These findings provide useful input for the future planning and design of high-rise residential areas.
Health and Well-Being through COVID-19 Vaccination: Physical, Oral, and Psychological Effects
Authors: Afrashtehfar Kelvin I. , Jurado Carlos A. , Abu-Fanas Salem H. , Jaber Mohamed A.
Published: February 2023

The Coronavirus Disease 2019 (COVID-19) pandemic and its evolving variants have spurred a worldwide effort to control its transmission and reduce its impact [...]
Feasibility of Developing Audiovisual Material for Training Needs in a Vietnam Orphanage: A Mixed-Method Design
Authors: Jovellar-Isiegas Patricia , Jiménez-Sánchez Carolina , Buesa-Estéllez Almudena , Gómez-Barreiro Pilar , Alonso-Langa Inés , Calvo Sandra , Francín-Gallego Marina
Published: February 2023

Disabled children living in orphanages in low-income countries may not have access to the therapy they need. The COVID-19 pandemic has complicated the situation dramatically, making online training activities a possible innovative option to meet the real needs of local staff. This study aimed to detect the training needs of the local staff of an orphanage in Vietnam, as well as develop an audiovisual training material and measure its feasibility. Training needs were identified through a focus group carried out by the volunteers of Fisios Mundi, a nongovernmental organization. The audiovisual training material was developed to meet these specific needs. Lastly, its feasibility was evaluated, in terms of both content and format, through an ad hoc questionnaire. Nine volunteers participated in the project. Twenty-four videos were created and structured around five themes. This study expands the body of knowledge on how an international cooperation project can be developed in a pandemic situation. The audiovisual training material content and format created in this project was considered by the volunteers as very feasible and useful for training the staff of a Vietnamese orphanage.
The Impact of Financial Development on Renewable Energy Consumption: A Multidimensional Analysis Based on Global Panel Data
Authors: Sun Zhongye , Zhang Xin , Gao Yifei
Published: February 2023

In this paper, we examined the impact of financial development on renewable energy consumption from a global perspective based on a dynamic panel model and panel data of 103 economies. We conducted the research from the different levels of financial development using an index system including nine variables, and also explored national heterogeneity by dividing samples into developed economies and developing economies. The empirical results indicated that the financial development had a positive impact on renewable energy consumption from the macro perspective, and this effect was mainly driven by the development of a financial institution (mainly including bank). Further analysis on the depth, access, and efficiency of a financial institution and financial market (mainly including stock market and bond market) revealed that all three aspects of a financial institution had a positive influence on renewable energy consumption, while this effect only existed in the aspect of efficiency for a financial market. The investigation of national heterogeneity showed that the financial development performed well in promoting renewable energy consumption in developed economies, while this positive effect only existed for financial institutions in developing economies. We suggest to policymakers to attach importance to the positive effect of financial development when formulating renewable-energy-related policies, and provide a system guarantee for renewable energy enterprises concerning financial sectors in developing economies.
Quantifying the Income-Increasing Effect of Digital Agriculture: Take the New Agricultural Tools of Smartphone as an Example
Authors: Luo Xin , Zhu Shubin , Song Zhenjiang
Published: February 2023

Smartphones are increasingly used in rural areas and have become indispensable new farming tools in farmers’ production and their lives. Based on data from the 2018 China Household Tracking Survey, this study uses ordinary least squares regression with two-stage least squares as a benchmark regression to investigate the impact of the extent of smartphone use on farm household income. Our findings are as follows. ① The degree of use of new smartphone farming tools has a significant income-increasing effect on farm households. ② There is variability in the impact of the use of new smartphone farming tools on the income of farmers in different regions. The highest income-generating effects on the use of smartphone tools were found in the western region, followed by the eastern region, with the smallest effects found in the central region. ③ Low-income farmers have the highest income effects from using new smartphone farming tools. We therefore recommend further improving the digital infrastructure in rural areas to give full play to the driving force of digital technology.
Mental Health of Healthcare Professionals: Two Years of the COVID-19 Pandemic in Portugal
Authors: Costa Alexandra , Caldas de Almeida Teresa , Fialho Mónica , Rasga Célia , Martiniano Hugo , Santos Osvaldo , Virgolino Ana , Vicente Astrid Moura , Heitor Maria João
Published: February 2023

The COVID-19 pandemic increased psychosocial risk factors among healthcare professionals (HCPs). Objective: To characterize Portuguese HCPs mental health (MH), estimate anxiety, depression, post-traumatic stress disorder (PTSD) and burnout symptoms, and identify risk/protective factors. A cross-sectional online survey and a longitudinal assessment were conducted in 2020 (T0) and 2021 (T1). Sociodemographic and occupational variables, COVID-19-related experiences and protective behavior data were collected from a non-probabilistic sample of HCPs in Portugal. Symptoms of anxiety, depression, PTSD, burnout and resilience were assessed using the Portuguese versions of the Generalized Anxiety Disorder Scale (GAD-7), the Patient Health Questionnaire (PHQ-9), the Post-traumatic Stress Disorder Checklist (PCL-5), the Shirom–Melamed Burnout Measure (MBSM) and the Connor–Davidson Resilience Scale (CD-RISC-10), respectively. Risk and protective factors were identified through simple and multiple logistic regression models. Overall, 2027 participants answered the survey in T0 and 1843 in T1. The percentage of moderate-to-severe symptoms decreased from T0 to T1; however, a considerable proportion of HCPs reported symptoms of distress in both years. Being a woman, working in a COVID-19-treatment frontline position and work–life balance increased the odds of distress. High resilience, good social/family support, and hobbies/lifestyle maintenance were found to be protective factors. Globally, our results show that performing as a HCP during the pandemic may result in long-term effects on MH.
Impact of Land Use Change on the Habitat Quality Evolution in Three Gorges Reservoir Area, China
Authors: Peng Chunhua , Wang Yanhui , Dong Junwu , Huang Chong
Published: February 2023

Habitat quality (HQ) is an important indicator to characterize the level of biodiversity and ecosystem services, and can reflect the quality of the human living environment. Changes in land use can disturb regional HQ. Current research mostly focuses on assessing the good or bad quality of regional habitats, and less on the spatial response relationship between land use change and HQ, and even fewer studies on finely distinguishing the impact of land use types on HQ. Therefore, taking Three Gorges Reservoir Area (TGRA) of China as the study area, this paper first analyzes the land use change of study area by using the land use transfer matrix, land use rate model and landscape pattern index, and then combines the InVEST model with the multi-scale geographically weighted regression (MGWR) model to build a refined assessment framework to quantitatively assess the spatial and temporal evolution patterns of HQ, and then analyse in detail the spatial response relationship of each land use type change on the impact of HQ. The results showed that from 2000 to 2020, the land use in the TGRA shows a changing state of “urban expansion, cultivated land shrinkage, forest land growth, and grassland degradation”. With the change in land use, the habitat quality index (HQI) in the study area showed an “ increase first and then decline” change characteristics, and the HQ degradation was more obvious in the areas with intense human activities. The impact of land use change over the past 20 years on HQ in the TGRA has significant spatial and temporal heterogeneity, with changes in paddy and dryland having mainly negative impacts on HQ, and changes in sparse land, shrubland, and medium-cover grassland having mainly positive impacts on HQ. This paper mainly provides a research framework for refined assessment, and the results can provide scientific support for land planning and ecological protection in the TGRA, and the research methods and ideas can provide references for similar research.
Where Am I Now? Modelling Disorientation in Pan-Scalar Maps
Authors: Touya Guillaume , Gruget Maïeul , Muehlenhaus Ian
Published: February 2023

Disorientation is a common feeling for all users of zoomable multi-scale maps, even for those with good orientation and spatial skills. We make the assumption that this problem is mainly due to the desert fog effect, documented in human–computer interaction within multi-scale zoomable environments. Starting with a collection of reported experiences of disorientation, this paper explores this notion from the spatial cognition, philosophical and human–computer interaction perspectives and proposes a model of disorientation in the exploration of multi-scale maps. We argue that disorientation is a problem of reconciliation between the current map view and the mental map of the user, where landmarks visible on the map or memorised in the mental map play a key role. The causes for failed reconciliation are discussed and illustrated by our collected experiences of disorientation.
An Expanded View on the Morphological Diversity of Long-Nosed Antlion Larvae Further Supports a Decline of Silky Lacewings in the Past 100 Million Years
Authors: Hassenbach Colin , Buchner Laura , Haug Gideon T. , Haug Carolin , Haug Joachim T.
Published: February 2023

Lacewings have been suggested to be a relict group. This means that the group of lacewings, Neuroptera, should have been more diverse in the past, which also applies to many ingroups of Neuroptera. Psychopsidae, the group of silky lacewings, is one of the ingroups of Neuroptera which is relatively species-poor in the modern fauna. Larvae of the group Psychopsidae, long-nosed antlions, can be easily identified as such in being larvae of antlion-like lacewings without teeth in their stylets (=compound structure of mandible and maxilla), with empodia (=attachment structures on legs) and with a prominent forward-protruding labrum. Therefore, such larvae can also be recognised in the fossil record. An earlier study demonstrated a decline in the morphological diversity of long-nosed antlion larvae over the past 100 million years. Here, we report several dozen new long-nosed antlion larvae and expand the earlier quantitative study. Our results further corroborate the decline of silky lacewings. Yet, a lack of an indication of saturation indicates that we have still not approached the original diversity of long-nosed antlions in the Cretaceous.
Differences in Male Mate Recognition between the Invasive Anoplophora glabripennis (Coleoptera: Cerambycidae) and Japanese Native A. malasiaca
Authors: Yasui Hiroe , Uechi Nami , Fujiwara-Tsujii Nao
Published: February 2023

The Asian longicorn beetle Anoplophora glabripennis is a recently arrived invasive species to Japan. The Japanese native A. malasiaca shows an extensive overlap with A. glabripennis with host plants, niches, and emergence season. Hybridization between these two species is suspected in Japan. The surface of the female is covered with contact sex pheromones that elicit male mating behavior within species. We evaluated the contact pheromonal activity of crude extract and fractions of female A. glabripennis coated on a black glass model and revealed a hydrocarbon fraction and a blend of fractions to show activity but relatively weak, suggesting the presence of other unknown active compounds. Few male A. glabripennis showed mating behavior when they were exposed to a crude extract of female A. malasiaca. However, a considerable number of A. malasiaca males mounted and showed abdominal bending behavior when presented with glass models that were coated with each extract of female A. glabripennis and A. malasiaca. Gomadalactones are essential contact pheromone components that elicit mating behavior in male A. malasiaca; however, we could not detect them in female A. glabripennis extract. Here, we investigated the possible reasons for this phenomenon and the difference in male mate recognition systems between these two species.
Nationwide Screening for Bee Viruses in Apis mellifera Colonies in Egypt
Authors: Kandel Mohamed , Paxton Robert , Al Naggar Yahya
Published: February 2023

Honey bees are essential for crop and wild plant pollination. However, many countries have reported high annual colony losses caused by multiple possible stressors. Diseases, particularly those caused by viruses, are a major cause of colony losses. However, little is known about the prevalence of honey bee pathogens, particularly virus prevalence, in Egyptian honey bees. To address this shortfall, we determined the prevalence of widespread bee viruses in honey bee colonies in Egypt—whether it is affected by geography, the season, or infestation with Varroa destructor (varroa) mites. Honey bee worker samples were collected from 18 geographical regions across Egypt during two seasons: winter and summer of 2021. Three apiaries were chosen in each region, and a pooled sample of 150 worker bees was collected from five colonies in each apiary then screened by qPCR for 10 viral targets: acute bee paralysis virus (ABPV), black queen cell virus (BQCV), chronic bee paralysis virus (CBPV), deformed wing virus (DWV) genotypes A (DWV-A), B (DWV-B) and D (Egyptian bee virus), Israeli acute paralysis virus (IAPV), Kashmir bee virus (KBV), sacbrood virus (SBV), and slow bee paralysis virus (SBPV). Our results revealed that DWV-A was the most prevalent virus, followed by BQCV and ABPV; the DWV genotype now spreading across the world, DWV-B, was not detected. There was no difference in varroa infestation rates as well as virus prevalence between winter and summer. However, colonies infected with BQCV had a significantly higher varroa count (adjusted p < 0.05) in the winter season, indicating that there is a seasonal association between the intensity of infestation by varroa and the presence of this virus. We provide data on the current virus prevalence in Egypt, which could assist in the protection of Egypt’s beekeeping industry. Moreover, our study aids in the systematic assessment of the global honey bee virome by filling a knowledge gap about the prevalence of honey bee viruses in Egypt.
Early Childhood Caries and Sleep Disorders
Authors: Arroyo Buenestado Ana , Ribas-Pérez David
Published: February 2023

Obstructive sleep-disordered breathing (oSDB) comprises a set of breathing disturbances when the individual is asleep due to partial or complete upper airway obstruction. Modifying or risk factors are the anatomy, the size and shape of the airway, muscle tone, central nervous system responses to hypoxia, etc. In children, this is associated with poor school performance and reduced memory and learning abilities. In addition, increased levels of blood and lung pressure and cardiac alterations have been reported in children with sleep disturbances. On the other hand, Early Childhood Caries (ECC) is defined as the presence of one or more decayed primary teeth (cavities) of children under the age of 5. This study aimed to establish the possible relationship between sleep disorders and ECC by means of validated surveys and determined whether the results obtained coincide with the available literature. Our results found that up to 24.5% of children with a high risk of caries present regular nasal congestion, while this finding is only present among 6% of children with a low risk of caries (p = 0.041). The dmft index remains significantly linked to this occasional congestion, but the association depends on the patient’s level of risk (p = 0.008); increasing with a high increasing risk of caries. As a conclusion, the risk of early childhood caries could correlate to a specific sleep change such as occasional snoring.
Diagnosis and Management of Neuropathic Pain in Spine Diseases
Authors: Bielewicz Joanna , Kamieniak Maciej , Szymoniuk Michał , Litak Jakub , Czyżewski Wojciech , Kamieniak Piotr
Published: February 2023

Neuropathic pain is generally defined as a non-physiological pain experience caused by damage to the nervous system. It can occur spontaneously, as a reaction to a given stimulus, or independently of its action, leading to unusual pain sensations usually referred to as firing, burning or throbbing. In the course of spine disorders, pain symptoms commonly occur. According to available epidemiological studies, a neuropathic component of pain is often present in patients with spinal diseases, with a frequency ranging from 36% to 55% of patients. Distinguishing between chronic nociceptive pain and neuropathic pain very often remains a challenge. Consequently, neuropathic pain is often underdiagnosed in patients with spinal diseases. In reference to current guidelines for the treatment of neuropathic pain, gabapentin, serotonin and norepinephrine reuptake inhibitors and tricyclic antidepressants constitute first-line therapeutic agents. However, long-term pharmacologic treatment often leads to developing tolerance and resistance to used medications. Therefore, in recent years, a plethora of therapeutic methods for neuropathic pain have been developed and investigated to improve clinical outcomes. In this review, we briefly summarized current knowledge about the pathophysiology and diagnosis of neuropathic pain. Moreover, we described the most effective treatment approaches for neuropathic pain and discussed their relevance in the treatment of spinal pain.
Current Frequency of Mandibular Condylar Process Fractures
Authors: Kozakiewicz Marcin , Walczyk Agata
Published: February 2023

There are significant discrepancies in the reported prevalence of condylar process fractures among all mandibular fractures (16.5–56%) in the available literature. In addition, it seems that the actual number of difficult-to-treat fractures of the mandibular head is unknown. The purpose of this study is to present the current incidence of the different types of mandibular process fractures with a special focus on mandibular head fractures. The medical records of 386 patients with single or multiple mandibular fractures were reviewed. Of the fractures found, 58% were body fractures, 32% were angle fractures, 7% were ramus fractures, 2% were coronoid process fractures, and 45% were condylar process fractures. The most common fracture of the condylar process was a basal fracture (54% of condylar fractures), and the second most common fracture was a fracture of the mandibular head (34% of condylar process fractures). Further, 16% of patients had low-neck fractures, and 16% had high-neck fractures. Of the patients with head fractures, 8% had a type A fracture, 34% had a type B fracture, and 73% had a type C fracture. A total of 89.6% of the patients were surgically treated with ORIF. Mandibular head fractures are not as rare as previously thought. Head fractures occur twice as often in the pediatric population than in adults. A mandibular fracture is most likely related to a mandible head fracture. Such evidence can guide the diagnostic procedure in the future.
Comparing Motor-Evoked Potential Characteristics of NEedle versus suRFACE Recording Electrodes during Spinal Cord Monitoring—The NERFACE Study Part I
Authors: Gadella Maria C. , Dulfer Sebastiaan E. , Absalom Anthony R. , Lange Fiete , Scholtens-Henzen Carola H. M. , Groen Rob J. M. , Wapstra Frits H. , Faber Christopher , Tamási Katalin , Sahinovic Marko M. , Drost Gea
Published: February 2023

Muscle-recorded transcranial electrical stimulation motor-evoked potentials (mTc-MEPs) are used to assess the spinal cord integrity. They are commonly recorded with subcutaneous needle or surface electrodes, but the different characteristics of mTc-MEP signals recorded with the two types of electrodes have not been formally compared yet. In this study, mTc-MEPs were simultaneously recorded from the tibialis anterior (TA) muscles using surface and subcutaneous needle electrodes in 242 consecutive patients. Elicitability, motor thresholds, amplitude, area under the curve (AUC), signal-to-noise ratio (SNR), and the variability between mTc-MEP amplitudes were compared. Whereas amplitude and AUC were significantly higher in subcutaneous needle recordings (p < 0.01), motor thresholds and elicitability were similar for surface and subcutaneous needle recordings. Moreover, the SNRs were >2 in more than 99.5% of the surface and subcutaneous needle recordings, and the variability between consecutive amplitudes was not significantly different between the two recording electrode types (p = 0.34). Surface electrodes appear to be a good alternative to needle electrodes for spinal cord monitoring. They are non-invasive, can record signals at similar threshold intensities, have adequately high SNRs, and record signals with equivalent variability. Whether surface electrodes are non-inferior to subcutaneous needle electrodes in detecting motor warnings is investigated in part II of the NERFACE study.
Does Having Rheumatoid Arthritis Increase the Dose of Depression Medications? A Mendelian Randomization Study
Authors: Wan Xianjie , Xie Jiale , Yang Mingyi , Yu Hui , Hou Weikun , Xu Ke , Wang Jiachen , Xu Peng
Published: February 2023

Background: Rheumatoid arthritis (RA) increases the risk of depression. However, studies on the effects of RA on the dose of depression medications are limited. Therefore, in this study, we used two-sample Mendelian randomization (MR) to explore whether RA increases the dose of depression medications and gain a more comprehensive understanding of the relationship between RA and depression. Methods: Two-sample MR was used to evaluate the causal effect of RA on the dose of depression medications. The aggregated data on RA originated from extensive genome-wide association studies (GWASs) of European descent (14,361 cases and 42,923 controls). The summary GWAS data for the dose of depression medications were derived from the FinnGen consortium (58,842 cases and 59,827 controls). Random effects inverse-variance weighted (IVW), MR-Egger regression, weighted median, and fixed effects IVW methods were used for the MR analysis. Random effects IVW was the primary method. The heterogeneity of the MR results was detected using the IVW Cochran’s Q test. The pleiotropy of the MR results was detected using MR-Egger regression and the MR pleiotropy residual sum and outlier (MR-PRESSO) test. Finally, a leave-one-out analysis was performed to determine whether the MR results were affected by a specific single-nucleotide polymorphism (SNP). Results: The primary method, random effects IVW, revealed that genetically predicted RA had a positive causal association with the dose of depression medications (Beta, 0.035; 95% confidence interval (CI), 0.007–0.064; p = 0.015). The IVW Cochran’s Q test results revealed no heterogeneity in the MR analysis (p > 0.05). The MR-Egger regression and MR-PRESSO tests revealed that there was no pleiotropy in our MR analysis. The leave-one-out analysis confirmed that a single SNP did not affect the MR results, indicating the study’s robustness. Conclusion: Using MR techniques, we discovered that having RA increases the dose of depression medications; however, the exact mechanisms and pathways still need to be further explored.
Vascular Function, Systemic Inflammation, and Coagulation Activation 18 Months after COVID-19 Infection: An Observational Cohort Study
Authors: Willems Loes H. , Jacobs Lotte M. C. , Groh Laszlo A. , ten Cate Hugo , Spronk Henri M. H. , Wilson-Storey Boden , Hannink Gerjon , van Kuijk Sander M. J. , Ghossein-Doha Chahinda , Nagy Magdi , Thijssen Dick H. J. , van Petersen André S. , Warlé Michiel C.
Published: February 2023

Introduction: Among its effect on virtually all other organs, COVID-19 affects the cardiovascular system, potentially jeopardizing the cardiovascular health of millions. Previous research has shown no indication of macrovascular dysfunction as reflected by carotid artery reactivity, but has shown sustained microvascular dysfunction, systemic inflammation, and coagulation activation at 3 months after acute COVID-19. The long-term effects of COVID-19 on vascular function remain unknown. Materials and Methods: This cohort study involved 167 patients who participated in the COVAS trial. At 3 months and 18 months after acute COVID-19, macrovascular dysfunction was evaluated by measuring the carotid artery diameter in response to cold pressor testing. Additionally, plasma endothelin-1, von Willebrand factor, Interleukin(IL)-1ra, IL-6, IL-18, and coagulation factor complexes were measured using ELISA techniques. Results: The prevalence of macrovascular dysfunction did not differ between 3 months (14.5%) and 18 months (11.7%) after COVID-19 infection (p = 0.585). However, there was a significant decrease in absolute carotid artery diameter change, 3.5% ± 4.7 vs. 2.7% ± 2.5, p—0.001, respectively. Additionally, levels of vWF:Ag were persistently high in 80% of COVID-19 survivors, reflecting endothelial cell damage and possibly attenuated endothelial function. Furthermore, while levels of the inflammatory cytokines interleukin(IL)-1RA and IL-18 were normalized and evidence of contact pathway activation was no longer present, the concentrations of IL-6 and thrombin:antithrombin complexes were further increased at 18 months versus 3 months (2.5 pg/mL ± 2.6 vs. 4.0 pg/mL ± 4.6, p = 0.006 and 4.9 μg/L ± 4.4 vs. 18.2 μg/L ± 11.4, p < 0.001, respectively). Discussion: This study shows that 18 months after COVID-19 infection, the incidence of macrovascular dysfunction as defined by a constrictive response during carotid artery reactivity testing is not increased. Nonetheless, plasma biomarkers indicate sustained endothelial cell activation (vWF), systemic inflammation (IL-6), and extrinsic/common pathway coagulation activation (FVII:AT, TAT) 18 months after COVID-19 infection.
Analysis of Flow Field Characteristics of Aquaculture Cabin of Aquaculture Ship
Authors: Xiong Zhixin , He Mingxuan , Zhu Wenyang , Sun Yu , Hou Xianrui
Published: February 2023

To investigate the influence of the number of inlet pipes on the characteristics of flow field and the discharge of solid particles such as bait residue and fish feces, STAR-CCM + was used to analyze the flow of field distribution in a ship-based aquaculture cabin under the conditions of two and four inlet pipes, thus optimizing the inlet pipes of the ship-based aquaculture cabin. Furthermore, a three-phase flow model (solid–liquid–gas) was established to determine the movement characteristics of similar solid particles of residual bait and fish manure in the cabin, while the emission performance of solid particles was analyzed. Finally, the formation of solid particles in the center of the aquaculture cabin was simulated. The simulation results show that the effect of flow field is better with two inlet pipes, and the discharge volume of the bottom outlet has little impact on the emission of solid particles. Findings from this study can serve as a reference and basis for the design and optimization of the aquaculture cabin of an aquaculture vessel.
Ferric Chloride Controls Citrus Anthracnose by Inducing the Autophagy Activity of Colletotrichum gloeosporioides
Authors: Wang Yuqing , Wu Xiaoxiao , Lu Yongqing , Fu Huimin , Liu Shuqi , Zhao Juan , Long Chaoan
Published: February 2023

Colletotrichum gloeosporioides causes citrus anthracnose, which seriously endangers the pre-harvest production and post-harvest storage of citrus due to its devastating effects on fruit quality, shelf life, and profits. However, although some chemical agents have been proven to effectively control this plant disease, little to no efforts have been made to identify effective and safe anti-anthracnose alternatives. Therefore, this study assessed and verified the inhibitory effect of ferric chloride (FeCl3) against C. gloeosporioides. Our findings demonstrated that FeCl3 could effectively inhibit C. gloeosporioides spore germination. After FeCl3 treatment, the germination rate of the spores in the minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) groups decreased by 84.04% and 89.0%, respectively. Additionally, FeCl3 could effectively inhibit the pathogenicity of C. gloeosporioides in vivo. Optical microscopy (OM) and scanning electron microscopy (SEM) analyses demonstrated the occurrence of wrinkled and atrophic mycelia. Moreover, FeCl3 induced autophagosome formation in the test pathogen, as confirmed by transmission electron microscopy (TEM) and monodansylcadaverine (MDC) staining. Additionally, a positive correlation was identified between the FeCl3 concentration and the damage rate of the fungal sporophyte cell membrane, as the staining rates of the control (untreated), 1/2 MIC, and MIC FeCl3 treatment groups were 1.87%, 6.52%, and 18.15%, respectively. Furthermore, the ROS content in sporophyte cells increased by 3.6%, 29.27%, and 52.33% in the control, 1/2 MIC, and MIC FeCl3 groups, respectively. Therefore, FeCl3 could reduce the virulence and pathogenicity of C. gloeosporioides. Finally, FeCl3-handled citrus fruit exhibited similar physiological qualities to water-handled fruit. The results show that FeCl3 may prove to be a good substitute for the treatment of citrus anthracnose in the future.
OCT Findings in Patients with Methamphetamine Use Disorder
Authors: Kaya Şüheda , Kaya Mehmet Kaan
Published: February 2023

Purpose: In the present study, the purpose was to examine the results of optical coherence tomography (OCT) measurements in patients diagnosed with methamphetamine use disorder (MUD) by comparing them with healthy controls. Materials and Methods: A total of 114 eyes were evaluated in this study (27 patients and 30 control group participants). After detailed biomicroscopic examinations of all participants by the same ophthalmologist, both eyes were evaluated by OCT. The retinal nerve fiber layer thickness (RNFL) and macular thickness were calculated from OCT. Results: No statistically significant differences were detected between the demographic data of the patient and control groups (p > 0.05). When OCT findings were evaluated, macular thickness and volume were not different between the groups (p > 0.05). With respect to RNFL, the left eye superior, inferior, temporal, and nasal quadrants, as well as the left eye’s total measurements were found to be thicker than those of controls (p < 0.05). In both eyes, the left eye nasal quadrant and APIS total score were negatively correlated, the total RNLF measurement of the right eye and APIS motivation subscale score were negatively correlated, central macular thickness and the APIS motivation subscale score were positively correlated, and the APIS substance use characteristics subscale score and left eye temporal quadrant RNLF measurement were positively correlated. Conclusion: Our study is the first to evaluate addiction severity and OCT findings in MUD. However, this study needs to be supported by further studies so that OCT findings, which can be used as an effective method for demonstrating possible neurodegeneration in methamphetamine use disorder, gain importance.
Understanding Nociplastic Pain: Building a Bridge between Clinical Psychology and Medicine
Authors: Galli Federica
Published: February 2023

Chronic pain (CP), defined as pain lasting more than three months, is a significant healthcare challenge with considerable economic costs [...]
Conversion of Forest Hillslopes into Tea Fields Increases Soil Nutrient Losses through Surface Runoff
Authors: Wang Yi , Liu Xinliang , Gan Yantai , Li Yong , Zhao Ying
Published: February 2023

The conversion of forest hillslopes into tea fields changes the slope structure, soil properties, and vegetation, which may increase the great variations in the nitrogen (N) and phosphorus (P) losses through the surface runoff and induce agricultural non-point source pollution, particularly during the first years of conversion. Therefore, a natural forest system and a newly reclaimed tea system were compared to determine the land use conversion effects on the surface runoff and resulting N and P losses during 2013–2016. The results showed that the soil bulk density (BD) at all the depths and the saturated soil conductivities (Ks) in the surface soil were higher in the tea system than in the forest system, indicating that great land use conversion impacts soil’s physical and hydraulic properties. The annual surface runoff volumes and ratios were significantly higher in the tea system than in the forest system (p < 0.05), and this increased surface runoff was largely attributed to the slope structure and soil property changes. The total P (TP), dissolved P (DP), and particle P (PP) concentrations in the surface runoff volumes were similar in the two systems, while the total N (TN) concentrations were higher in the tea system than in the forest system due to the high N fertilizer application rates in the tea system. The percentages of dissolved N (DN) in the TN and particle N (PN) in the TN were, respectively, lower and higher in the tea system than in the forest system, which was associated with increased soil erodibility due to the land use conversion. The mean annual N and P losses through the surface runoff were higher in the tea system (11.07 ± 4.03 kg N ha−1 yr−1 and 1.73 ± 0.19 kg P ha−1 yr−1) than in the forest system (4.51 ± 0.66 kg N ha−1 yr−1 and 0.78 ± 0.18 kg P ha−1 yr−1). The N and P losses exponentially correlated with the surface runoff in both systems; however, the coefficients of determination (R2) were higher in the forest system than in the tea system, indicating that the exponential relationship between the surface runoff and the N and P losses should be more stable in the forest system than in the newly reclaimed tea system. Therefore, more effort should be dedicated to reducing the N and P losses though the surface runoff when forest hillslopes are converted into tea fields, particularly during the first three years of conversion.