bluuebunny/crossref_metadata_2025 huggingface dataset:
Earthquake Triggered Multi-Hazard and Risk Study Based on Remote Sensing and Geographic Information System
Authors: Saputra Aditya , Gomez Christopher , Delikostidis Ioannis , Zawar-Reza Peyman , Hadmoko Danang Sri , Sartohadi Junun
Published: December 2018

Yogyakarta City is one of the big city which is located in Java Island, Indonesia. Yogyakarta City, including study area (Pleret Sub District), are very prone to earthquake hazards, because close to several active earthquake sources. For example, Sunda Megathrust which often generates a big earthquake which can affect the study area. The Sunda Megathrust extends from north to south and west to east along the Sumatra and Java Islands. Furthermore, an active normal fault called as Opak Fault pass through right in the middle of Study area and divides the study area into east and west zone. Recently, after the devastating earthquake in 2006, the population of the study area increases significantly. As a result, the housing demand is also increasing. However, due to the absence of earthquake building code in the study area, locals tend to build improper new houses. Furthermore, in some part of the mountainous area in the study area, there are some building found in unstable slopes area. Due to this condition, the multi-hazard and risk study needs to be done in Pleret. The increasing of population and improper houses in Pleret Sub-District can lead to amplify the impact. Thus, the main objective of this study is to assess the multi-hazards and risk of earthquake and other related secondary hazards such as ground amplification, liquefaction, and coseismic landslide.  The method mainly utilised the geographic information system, remote sensing and was fit up by the outcrop study. The results show that the middle part of the study area has a complex geological structure. It was indicated by a lot of unchartered faults was found in the outcrops. Furthermore, the relatively prone areas to earthquake can be determined. In term of the coseismic landslide, the prone area to the coseismic landslide is located in the east part of the study area in the middle slope of Baturagung Escarpment. The highly potential area of liquefaction is dominated in the central part of the study area. In term of building collapsed probability, the result shows that the safest house based on statistical analysis is the residential house with the building attribute of wood structure, roof cast material, distance more than 15 km from the earthquake source, and located above the Nglanggran Formation. Finally, the multi-hazard and risk analysis show that the middle part of the study area is more vulnerable than the other part of Pleret Sub-District.
Effects of Selective Substitution of Cysteine Residues on the Conformational Properties of Chlorotoxin Explored by Molecular Dynamics Simulations
Authors: Gregory Andrew J. , Voit-Ostricki Leah , Lovas Sándor , Watts Charles R.
Published: December 2018

Chlorotoxin (CTX) is a 36–amino acid peptide with 8 Cys residues that forms four Cys-Cys bonds. It has high affinity for the glioma-specific chloride channel and matrix metalloprotease-2. Structural and binding properties of CTX analogs with various Cys residue substitutions with L-a-aminobutyric acid (Abu) have been previously reported. Using 4.2 ìs molecular dynamics, we compared the conformational and essential space sampling of CTX and analogs [Abu/Ser2,19]CTX, [Abu/Ser5,28]CTX, [Abu/Ser16,33]CTX, [Abu/Ser20,35]CTX, and [Abu/Ser2,5,16,19,20,28,33,35]CTX. The native and substituted peptides maintained a high degree of a-helix propensity from residues 8 through 21, with the exception of [Ser5,28]CTX and [Abu16,33]CTX. In agreement with previous circular dichroism spectropolarimetry results, the C-terminal b-sheet content varied less from residues 25 through 29 and 32 through 36 and was well conserved in all analogs, except: [Abu16,33]CTX, [Ser20,35]CTX, [Abu2,5,16,19,20,28,33,35]CTX, and [Ser2,5,16,19,20,28,33,35]CTX. The Cys16-Cys33 and Cys20-Cys35 Cys-Cys bonds appear to be required to maintain the ab-motif of CTX. Their selective substitution with Ser16,33 however, may mitigate the destabilizing effect of Cys16-Cys33 substitution by the formation of an inter residue H-bond from OgH of Ser16 to OgH of Ser33 bridged by a water molecule. All peptides shared considerable sampled conformational space, which explains the retained receptor binding of the nonnative analogs.
Mavi Renklenme Zararının Tomrukların Endüstriyel İşlenme Özellikleri Üzerine Etkileri
Authors: KOMUT Osman , ÖZTÜRK Atakan
Published: December 2018

Mavi renklenme
tomruk, kereste ve kullanım yerlerindeki malzemede estetik karakteristikler ve
mekanik şok direncinde neden olduğu değişimler dolayısıyla önemli ekonomik
kayıplara yol açmaktadır. Diğer yandan, zarara maruz kalmış malzemede emprenye
ve üst yüzey işlemlerindeki başarı oranının düşük olmasının tomruğun
endüstriyel kullanım alanlarını önemli ölçüde sınırlandırdığı
bilinmektedir.  Bu çalışma mavi renklenme
zararının, tomruk işleyen orman endüstri işletmeleri üretim süreci üzerindeki
etkilerini ve neden olduğu kayıpları belirlemeyi amaçlamıştır. Araştırma,
Gümüşhane ilinde Sarıçam tomruğu işleyen toplam 9 küçük ve orta ölçekli kereste
üretim işletmesinde gerçekleştirilmiştir. Çalışmada, mavi renklenme zararının
boyutu tomruk toplam hacmine oranlanarak değerlendirilmiştir.  Diğer yandan, inşaat ve doğrama sektörlerine
yönelik üretim gerçekleştiren işletmeler arasında, mavileşme sonucu oluşan
tahribat yönünden karşılaştırmalar yapılmıştır. Çalışma sonucunda, mavi
renklenme tahribatında hacmen zarara maruz kalma oranının diri odun genişliği,
tomruk boy ve çap değişkenlerine bağlı olmak üzere %32-84 arasında değiştiği belirlenmiştir.
 Ayrıca, inşaat ve doğrama sektörlerine
yönelik kereste üretimi yapan işletmeler arasında tomruk enine kesit yüzeyindeki
mavileşmiş alan genişliği ve bozuk hacim oranı değişkenlerine göre istatistiksel
düzeyde anlamlı farklılıklar bulunduğu (p<0,05) tespit edilmiştir. Diğer
yandan, inşaat sektörüne yönelik üretim yapan kereste işletmelerinde mavi
renklenme zararının göz ardı edildiği görülmüştür. Doğrama sektörüne yönelik
üretim yapan işletmelerde ise malzemenin görsel niteliklerinin iyileştirilmesi
amacıyla mavileşmiş kısmın uzaklaştırıldığı, ancak bu işlem dolayısıyla ilave enerji
ve işgücü maliyetlerinin oluştuğu tespit edilmiştir.
In vitro anticoagulant and antiinflammatory activities of Geastrum fimbriatum Fr., namely as Earthstar fungus
Authors: SARAC Nurdan , ALLİ Hakan , BAYGAR Tuba , UGUR Aysel
Published: December 2018

Mushrooms have great potential to be used as food and
pharmaceutical sources. Most of the non-edible mushrooms contain biologically
active metabolites that are functional for modern medicinal applications.
Within the present study, anticoagulant and antiinflammatory activities of Geastrum fimbriatum Fr. (Syn. Geastrum sessile (Sowerby) Pouzar), a
mushroom naturally grown in Turkey, were investigated. The in vitro anticoagulant activity of the ethanolic extract obtained
with a soxhlet apparatus determined by activated partial thromboplastin time (APTT) and
prothrombin time (PT) assays using commercial reagents. The
antiinflammatory activity of the extract was determined by lipoxygenase
inhibition assay. When
compared with the negative control DMSO, G.
fimbriatum extract exhibited significant anticoagulant effects in
the APTT test that evaluates the intrinsic coagulation pathway. The ethanolic
extract found to prolong the coagulation time. However, no inhibition was
observed in the PT test which evaluates the extrinsic coagulation pathway, The
extract showed 12.92% inhibition on the lipoxygenase enzyme activity. Overall, G. fimbriatum ethanolic extract
exhibited potent antiinflammatory activity besides being a potential source of
anticoagulant. Further analysis is
required to evaluate the medical use of Geastrum
mushrooms from a pharmaceutical point of view.
Effects of Nitrate toxicity on free Proline accumulation, chlorophyll degradation and photosynthetic efficiency in Chlorella vulgaris Beyerinck [Beijerinck]
Authors: TÜNEY KIZILKAYA İnci , UNAL Dilek
Published: December 2018

The
effects of high nitrate concentrations on alterations in maximal photochemical
efficiency of PSII ratio (Fv/Fm), chlorophyll content, chlorophyll degradation,
growth rate and proline accumulation in Chlorella vulgaris Beyerinck
[Beijerinck] were investigated in this study. The Fv/Fm ratio was
observed in response to the increased nitrate concentration. The Fv/Fm ratio
decreased in C. vulgaris following 44 h in 12.99 mM NaNO3-enriched
media. Experimental results showed that, growth rates and chlorophyll content
declined by increasing nitrate concentration. The decrease in the ratio of
chlorophyll a/b with enrichment of high nitrate concentration (6.5 mM and 12.99
mM NaNO3) was also caused by a decrease in chlorophyll a and an
increase in chlorophyll b concentration in C. vulgaris cultures. The
results showed that 6.5 and 12.99 mM nitrate concentration increased proline
content in treated cells, which suggests that nitrate stress lead to proline
accumulation in C. vulgaris.
Analisis Online Impulse Buying dengan menggunakan Framework SOR
Authors: Syastra Muhammad Taufik , Wangdra Yvonne
Published: December 2018

Electronic commerce (e-commerce) transactions in a country must be continuously improved to support the country's economic development. E-commerce owner are looking for efforts / strategies to increase sales. The effort that can be done is to conduct an study of impulsive purchases online. The framework used to conduct this study is SOR (Stimulus, Organism and Response). The purpose of this study is to identify the factors causing impulsive purchases online and which factors that have the highest contribution. This study focuses on mainstream e-commerce websites such as: tokopedia, lazada, bukalapak, shopee, and elevenia. The number of respondents was 105 people. Data analysis techniques are Descriptive Analysis. To strengthen the data, the researchers conducted interviews with 10 respondents. The findings of this study are the factors causing impulsive purchases: (1) Promotion / discounts; (2) Flash sale; (3) Popular this week item; (4) Hot list product; (5) Payment installment facilities. Factors that have the highest contribution are Promo / discount with a value of 64.8%. Promos / discounts are the most influential an impulsive buying desire in conventional markets and e-commerce
The Herbalist Game Edukasi Pengobatan Herbal Berbasis Android
Authors: Afrianto Irawan , Furqon Rifan Muhammad
Published: December 2018

Herbal treatment is a method of treatment using natural ingredients that are all around us. Introducing herbal medicines and treatments can be performed using educational games. The purpose of this research is to develop educational games that can teach users to be able to know the ingredients of herbs and how to process it into a drug to cure a disease. The method used in the development of this educational game is multimedia development life cycle (MDLC). The MDLC method is used to develop this educational game, starting with the concept definition stage, the design phase, followed by the collecting material stage, followed by the assembly stage, testing, and ending with the distribution stage. This educational game is a type of simulation that visualizes the form of herbal ingredients, and how to manufacture herbal medicine derived from these materials to cure a disease. Games using mobile devices have advantages that learning can be done anywhere and anytime, so the android platform is chosen as the media development of this educational game. Educational game testing is done using the alpha method to determine the functionality of the application, and beta test to the user. Alpha testing shows that every functionality in this educational game has gone well. While beta testing conducted with questionnaires shows that this educational game is enough to help users add knowledge about herbal ingredients and how to make herbal remedies through images, animation and how to play. In addition, the interface of this game is quite interesting and easy to use.
Pengukuran Penerimaan Sistem Informasi EWSKIA Berdasarkan Persepsi Pengguna dengan Menggunakan Technology Acceptance Model
Authors: Widodo Aris Puji , Agushybana Farid , Jati Sutopo Patria
Published: December 2018

This study is a quantitative research that has a goal to measure the level of user acceptance of EWSKIA information system based on perception. EWSKIA is a healthcare application tool used to perform the process of recording and monitoring the health conditions of pregnant and childbirth mothers. The model used in this research is using Technology Acceptance Model (TAM) model with 3 variables, namely Perceived Ease of Use (PEOU), Perceived Usefulness (PU), and Behavioral Intention to Use (BITU). This variable consists of independent variables namely PEOU and PU, and the dependent variable is BITU. The respondents were 145 midwives from Grobogan District, Temanggung Regency and Salatiga City. Data analysis to conduct causal relationships between variables using Partial Least Square (PLS). The results of this study statistically show that the 3 hypotheses of H1, H2, and H3 adopted from the TAM model have a positive and significant influence. This is indicated by the value of the regression coefficient is positive and the coefficient of P value is less than 0.005
Metode Moment Invariant Geometrik untuk Menganalisis Jenis Daging Babi dan Daging Sapi
Authors: Nurhayati Oky Dwi , Hastuti Isti Pudji
Published: December 2018

Beef needs have increased every year. So as the need for expensive beef even at certain times tends to rise. This is used by cheat seller to mix beef with pork because pork is relatively cheaper. This is very detrimental to consumers. Visually, many peoples (consumers) couldn’t distinguish these two types of meat. Hence, we conduct research to distinguish both types of meat.  One way to overcome these problems is the use of complete image processing techniques. The aim of this research was establised an application prototype to distinguish beef and pork with image processing techniques. Image processing method is used to distinguish the types of meat done by pre-processing, segmentation, feature extraction with geometrical moment invariant and K-NN classification. Geometric moment invariant method proposed to analyze beef and pork is done by extracting unique values from each images. This method can be used as a description of the form based on the moment theory. The results showed that the image processing method and K-NN classification with a value of k = 3 used in the research could significantly  used to analyze the type of meat namely beef and pork. The other difference can be shown from the phi moment invariant value, especially the value of phi (1) and phi (2)
Accounting systems in developing countries under sustainability: first glance from Ukraine and Ghana
Authors: Makarenko Inna , Adu Stephen
Published: December 2018

The dissemination of sustainability reporting and integrated reporting is a key trend in the development of accounting systems under the influence of the concept of sustainable development. This statement is fair not only for developed countries, but also for developing countries. On the example of Ghana and Ukraine, a comparative study of regulatory requirements and conceptual frameworks for the compilation of sustainability reporting and integrated reporting has been conducted; the dynamics, size of reporting companies, their sectoral affiliation and the standards used are researched. It was proved that the basis for the promotion sustainability reporting and integrated reporting in these countries are regulatory requirements, as well as increasing the perception of CSR, the transparency and accountability of business, the practices of stakeholder participation and assurance the reliability of reporting for stakeholders.
Exchange rates: the influence of political and economic events. а fundamental analysis approach
Authors: Gamaliy Volodymyr , Shalimova Nataliia , Zhovnovach Ruslana , Zahreba Maksym , Levchenko Anna
Published: December 2018

The objective of the article is to study the influence of political and economic factors on the situation on the world foreign exchange market, substantiate the importance of fundamental analysis in forecasting currency rates. The concept and mechanisms of functioning of the world currency market, its assets and specific features in comparison with other financial platforms are considered in the article. The need for special attention to fundamental analysis during the periods of global political and economic events is grounded. Based on the analysis of the dynamics of the leading world currency pairs in recent years, the period from October 2016 to April 2017 was chosen for an analysis because that period is full of significant events in the world political and economic arena, which are powerful levers of the traders’ behavior, and hence the direction of the dynamics of key currency pairs. These events are as follows:

presidential elections in the USA;
two increases of the Federal Reserve rate; and
the policy of the European Central Bank, aimed at stimulating inflation.

It is substantiated that using the fundamental analysis makes it possible to assess the trend and scale of changes in the rates of the world currencies, and in combination with technical analysis is an integral tool for successful trading and forecasting the dynamics of currency pairs. The possibility of using the mechanisms of functioning of such fundamental analysis tool as artificial neural networks and the ways of their application in solving such problems has been considered.
“Rollin’ on the River”: what economic and political factors caused restoration of service for the Gee’s Bend public ferry?
Authors: R. Jett Terri , Gentle Paul
Published: December 2018

This article presents a case study on the efforts to reestablish ferry service for an isolated island-type community in Wilcox County, Alabama, known as Gee’s Bend or by the formal name of Boykin. Gee’s Bend, a community of inhabitants who can trace their ancestry to slaves on the antebellum plantation there, depended on the ferry to provide access to the county seat of Camden, the center for social and economic activity. There was no ferry between 1962 and 2006. For forty-four years the ferry did not operate, having had its’ cable deliberately cut so that Gee’s Bend residents could not get to Camden to register to vote. It was an attempt to lessen the political power of the African-Americans in the area. This article explains the key economic and political factors that resulted in restoration of service for the Gee’s Bend ferry.
Macro level analysis of factors contributing to value added: technological changes in European countries
Authors: Antoniuk Larysa , Cherkas Nataliia
Published: December 2018

In conditions of globalization and rapidly growing production fragmentation, generation of value added becomes an ultimate goal and a measure of economic performance. The study provides an analysis of factors contributing to value added at macro level in different European countries. The analysis includes a panel framework covering 27 European countries over the period 2006–2015. In order to investigate the differences across regions, three subsamples are considered, namely, developed economies, PIIGS (Portugal, Italy, Ireland, Greece and Spain) and Central-Eastern European Countries (CEEC). Pooled OLS, fixed effects and random effects models are used. The results indicate that increase of value added corresponds to budget discipline, quality of human capital improvement, strong currency and transparent institutions. It could be expected that currency depreciation improves performance of the value added of exported final goods. However, the results show the opposite evidence: currency depreciation causes the value added decrease in all groups. Thus, for transitional countries, it is im¬portant not only to join global production chains, but also to acquire a significant share in generation of value added in these chains based on technological changes.
HOW TO TREAT VTEC IN CANCER PATIENTS IN THE ACUTE PERIOD? EXTENDED TREATMENT. THE ROLE OF DIRECT ORAL ANTICOAGULANTS. THE RESULTS OF HOKUSAI VTE CANCER STUDY
Authors: Fedotkina Yulia A.
Published: December 2018

Cancer is one of the most significant risk factors for venous thromboembolic complications (VTEC). The article discusses the features of the treatment of cancer patients with VTEC. The issues of alternative anticoagulant therapy are considered. The article presents the results of HOKUSAI VTE Cancer study, the first completed study to compare the efficacy and safety of a direct oral anticoagulant endoxaban with a low molecular weight heparin dalterapin for the treatment of VTEC in cancer patients.
ADDITIVE EFFECT OF GENES POLYMORPHISM OF FOLATE CYCLE PROTEINS AND HOMOCYSTEIN LEVEL IN PATIENTS WITH PROLIFERATIVE DISEASES OF THE BREAST AS A POTENTIAL FACTOR OF THE RISK OF THROMBOSSES
Authors: Markovsky Aleksandr V.
Published: December 2018

Aim.The aim of study was to examine the relationship between serum and mammary gland homocysteine levels with the carrier of separate SNP (single nucleotide polymorphism) genes of the folate metabolism system in patients with proliferative diseases and breast cancer.Methods and results.The study included 182 patients with proliferative diseases of the mammary gland in transbaikalia. The control group included 144 women who did not have oncological diseases. The serum homocysteine level and the supernatant of the mammary tissue homogenate were evaluated by high performance liquid chromatography. Genotyping for the detection of polymorphism MTHFRС677T, MTHFRА1298C, MTRA2756G, MTRRA66G was carried out by polymerase chain reaction with the detection of the amplification product in real time. In the course of molecular genetic testing in patients with proliferative diseases of the mammary gland, there was found: 1) the absence of an explicit association of the carriage of genetic polymorphism MTHFRС677T, MTHFRА1298C, MTRA2756G and MTRRA66G with serum homocysteine concentration, however, comparative hyperhomocysteinemia and, to a lesser extent, in women with the benign breast diseases; 2) the highest homocysteine content in the blood in patients with breast cancer whose genotype was characterized by combinations of polymorphic alleles MTR2756G x MTRR66G; 3) that the MTR2756A allele and genotype MTHFR1298AC, especially their combination of MTHFR1298AC x MTR2756A, increase the risk of developing benign breast formations; 4) the effect of the risk alleles MTR2756G and MTRR66GON the concentration of homocystein in the tumor tissue of the mammary gland.Conclusion. These patterns indicate a certain contribution of the polymorphisms studied, especially their additive effect, both in the development of proliferative diseases of the mammary gland and in the possible potentiation of prothrombotic effects in these patients against the background of tumor progression and homocysteine metabolism disorders.
ATRIAL FIBRILLATION COMBINED WITH DIABETES MELLITUS. POSSIBILITIES OF USING RIVAROXABAN
Authors: Ehrlich Alexey D.
Published: December 2018

The presented material summarizes the main clinical and theoretical data on the peculiarities of atrial fibrillation (AP) flow in combination with diabetes mellitus (DM). This combination, although associated with a lower age than in patients without diabetes, is associated with a higher risk of stroke and systemic embolism and other adverse complications. The material presents the data of the rocket-AF randomized trial subanalysis on the peculiarities of the use of oral anticoagulant - a direct inhibitor of Xa-factor Rivaroxaban in patients with non-valve AF in combination with DM. Comparative efficacy and safety of Rivaroxaban in patients with diabetes were comparable to those in patients without diabetes. Rivaroxaban in patients with diabetes was associated with lower vascular death rates than warfarin. The results of the randomized trial are largely confirmed in several observational studies that reflect actual clinical practice. Thus, it can be affirmed that Rivaroxaban is not only the most commonly used direct oral anticoagulant in russian practice, but can also be widely used in patients with non-valve AF and diabetes to prevent strokes and systemic embolisms.
DESIGN OF A ROBOTIC TOY AND USER INTERFACES FOR AUTISM SPECTRUM DISORDER RISK ASSESSMENT
Authors: UNCULAR Deniz , ARTUT Selçuk
Published: December 2018

Autism Spectrum Disorder (ASD) is an umbrella term for a spectrum of
complex developmental disorders resulting in deficits in social communication
and repetitive and stereotyped behaviors (APA, 2013). Research in the area
revealed that young children with ASD are interested in technology. This
preference for technology may lead to promising intervention models (Annaz et
al., 2012; Klin et al., 2009; Fong et al., 2003). This paper includes research
into how to design and use technology to create suitable products for deficits
of ASD. With all the concern over the high prevalence ratios of ASD, this study
presents the methodology and design of a risk assessment device, which aims to
capture the interest of children with ASD aged 3-4, and direct children who score
low on the tests towards a diagnosis. The tests in the device are designed to
detect differences with ToM tests between ASD and typically developing (TD)
children. In the scope of the paper, 2D illustrations, interface design, and
outer shell design of the device are created in compliance with the research
data in the field.
Metal Filament İçeren İpliklerden Üretilen Süprem Örme Kumaşların Farklı Doğrultulardaki Yüzey Özdirençlerinin İncelenmesi
Authors: ÖZKAN İlkan
Published: December 2018

Bu çalışmada bakır/çelik monofilament ve metalize gümüş multifilament içeren ipliklerden üretilen örme kumaşların farklı doğrultulardaki yüzey özdirenç değerleri incelenmiştir. Bu kapsamda iletken filamentler (metalize gümüş, bakır, paslanmaz çelik) eşkarıştırma (commingling) tekniği kullanılarak tekstüre polyester filament iplikler ile birleştirilmiştir. Üretilen metal içerikli ipliklerden süprem örgü yapısında numune kumaşlar üretilmiştir. Üretilen numune örme kumaşlara sıra ve çubuk doğrultusunda yüzey özdirenç testleri uygulanmıştır. Mikroskop görüntüleri kullanılarak iplik ve kumaş numunelerinin yüzey yapıları detaylı olarak incelenmiştir. Veriler istatistiksel teknikler ile analiz edilmiş ve sonuçlar karşılaştırmalı olarak değerlendirilmiştir. Araştırma sonuçları metal içerikli ipliklerden üretilen örme kumaşların daha düşük özdirenç değerine sahip olduğunu göstermiştir.
Adsorption mechanism of dichlorvos onto coconut fibre biochar: the significant dependence of H-bonding and the pore-filling mechanism
Authors: Binh Quach An , Kajitvichyanukul Puangrat
Published: December 2018

The adsorption mechanism of dichlorvos onto coconut fibre biochar (CFB) was investigated by the batch adsorption technique. Coconut fibre waste material was synthesised at 600 °C for 4 h under oxygen-limited conditions. The biochar was modified by HCl acid to enhance the specific surface area and porosity. The characteristics of the biochar were analysed by scanning electron microscopy (SEM), Brunauer–Emmett–Teller (BET) specific surface area, and Fourier transform-infrared (FT-IR). The results showed that the BET speciﬁc surface area of biochar was 402.4 m2/g. Experimental data presented a good fit to Langmuir isotherm and the pseudo-second-order model. Langmuir isotherm illustrated that monolayer adsorption of dichlorvos occurred on the surface of CFB, with a maximum adsorption capacity of 90.9 mg/g. The diffusion model confirmed that the liquid film diffusion was the rate-limiting step, and the major diffusion mechanism of dichlorvos onto biochar. The BET result after dichlorvos adsorption demonstrated that pore-filling occurred and occupied 58.27%. The pore-filling and chemical interactions, performed important roles in the adsorption of dichlorvos onto CFB. Chemical adsorption is comprised of two interactions, which are hydrophobic and H-bonding, but the prime is H-bonding. CFB is a very potential material for the removal of dichlorvos and environmental pollutants.
Why Should Psychiatrists and Neuroscientists Worry about Paraoxonase 1?
Authors: Moreira Estefania Gastaldello , Boll Karine Maria , Correia Dalmo Guilherme , Soares Janaina Favaro , Rigobello Camila , Maes Michael
Published: December 2018

Background:

Nitro-oxidative stress (NOS) has been implicated in the pathophysiology
of psychiatric disorders. The activity of the polymorphic antioxidant enzyme paraoxonase 1 (PON1)
is altered in diseases where NOS is involved. PON1 activity may be estimated using different substrates
some of which are influenced by PON1 polymorphisms.

Objectives:

1) to review the association between PON1 activities and psychiatric diseases using a
standardized PON1 substrate terminology in order to offer a state-of-the-art review; and 2) to review
the efficacy of different strategies (nutrition, drugs, lifestyle) to enhance PON1 activities.

Methods:

The PubMed database was searched using the terms paraoxonase 1 and psychiatric diseases.
Moreover, the database was also searched for clinical trials investigating strategies to enhance
PON1 activity.

Results:

The studies support decreased PON1 activity as determined using phenylacetate (i.e.,
arylesterase or AREase) as a substrate, in depression, bipolar disorder, generalized anxiety disorder
(GAD) and schizophrenia, especially in antipsychotic-free patients. PON1 activity as determined
with paraoxon (i.e., POase activity) yields more controversial results, which can be explained by the
lack of adjustment for the Q192R polymorphism. The few clinical trials investigating the influence
of nutritional, lifestyle and drugs on PON1 activities in the general population suggest that some
polyphenols, oleic acid, Mediterranean diet, no smoking, being physically active and statins may be
effective strategies that increase PON1 activity.

Conclusion:

Lowered PON1 activities appear to be a key component in the ongoing NOS processes
that accompany affective disorders, GAD and schizophrenia. Treatments increasing attenuated
PON1 activity could possibly be new drug targets for treating these disorders.
Lewis Acid Surfactant Combined (LASC) Catalyst as a Versatile Heterogeneous Catalyst in Various Organic Transformations
Authors: Singh Ruby , Bhardwaj Diksha , Ganaie Shakeel Ahmad , Singh Aakash
Published: December 2018

Surfactant Aided Lewis Acids (LASCs) make an appearance as one of the efficient and
substantial heterogeneous catalysts. Recently, various LASCs have been used as green and heterogeneous
catalysts in organic synthesis due to their high water stability, recyclability, cost-effective nature
and their ability to create stable colloidal dispersions. In the present review, we have discussed a
variety of carbon-carbon bond forming, ring opening, addition and multi-component reactions for the
synthesis of various biologically important heterocyclic compounds that have been successfully catalyzed
by LASCs. In most cases, the catalytic activity of LASCs was found to be better in water in
comparison to other organic solvents, which attracts special attention towards the present review.
Mechanical and Electromagnetic Analysis of High Speed Motor/Generator for Electric Turbo Compounding System
Authors: Choi Bongseok , Jung Donghoon , Lee Jaek wang , Lee Ju
Published: December 2018

Background:

Recently, environment friendly technologies are being introduced as global warming is rapidly progressing. One of the effective way to reduce the problem, Electric Turbo Compounding System has been researched globally. With this system, about 30% exhaust gas can be recycled as a power source. Therefore, this system is effective for engine systems with purposes such as downsizing and increasing efficiency of the system.

Objective & Method:

Surface mounted Permanent Magnet Motor is applied to this system due to its high efficiency, power density, small size, and low weight. However, during high speed operation, a retaining sleeve is essential in rotor such as Inconel 718 to satisfy a mechanical safety factor of the rotor. In this paper, through basic theory, the sleeve thickness is predicted according to the permanent magnet dimension and minimum sleeve thickness is determined satisfying mechanical safety factor by mechanical analysis. Furthermore, by electromagnetic analysis output characteristics according to the permanent magnet dimension having same constraints such as volume, current density, current and flux distribution are compared.

Result & Conclusion:

Based on the results of the electromagnetic analysis and mechanical analysis, the appropriate ratio of electric and magnetic loading is determined with equivalent constraint condition. Consequently, only model 2 satisfies the requirement at rated and maximum speed within the current limit.
Spatial Correlation of Cone Tip Resistance for Soil in Nasiriyah
Authors: Shakir Ressol R.
Published: December 2018

Background:

Quantification of soil property spatial variations is an important step in any reliability-based design. Little stochastic parameter information about the soil in Nasiriyah, which is in southern Iraq, is available.

Methods:

In this paper, the Scale Of Fluctuation (SOF) for the site soil is examined, which is suggested for construction of the refinery fuel station project as no random parametric quantity has been studied in this region. A Cone Penetration Test (CPT) was performed as part of the site investigation to a depth of 20 m in the vertical direction, and 24 CPTs were analyzed within the site. The spatial correlation was computed using four methods, including Single Exponent (SNE), Square Exponent (SQE), Cosine Exponent (CSE) and Second-Order Markov (SOM). Identification of the soil type depended on the most recent classification chart, which is based on CPT results. The spatial correlation was evaluated for the vertical direction considering the cone tip resistance (qc) component. Three trend functions were applied to all CPT soundings, including linear, quadratic and cubic polynomials, which were utilized to transform the non-stationary data to stationary data. Three modes of soil were employed, including the eight-meter soil layer, a twelve-meter soil layer and the entire twenty meters of soil, which includes both layers.

Results and Discussion:

The mean values of SOF were 0.54 m, 0.53 m, and 1.73 m for soil layers 8 m, 12 m, and 20 m, respectively. The high value of the last mean is attributed to the 20 m of stratification in the ground. This study also indicates that the SOF decreases as the polynomial degree increases, which is due to enhanced fitting. The coefficient of variation (COV) for the SOF shows little variability for most of the studied soil cases.
Regulation of Biogenesis and Fusion/Fission Processes of Vascular Mitochondria In Aldosterone-Induced Hypertension
Authors: Olivares-Álvaro Elena , Ruiz-Roso María Belén , Klett-Mingo Mercedes , Ballesteros Sandra , Gredilla Ricardo , Galiana-Simal Adrián , de las Heras Natalia , Lahera Vicente , Martín-Fernández Beatriz
Published: December 2018

Background:

Aldosterone plays a key role in the development of endothelial dysfunction and hypertension. The regulation of biogenesis and fusion/fission processes of vascular mitochondria has not been examined in aldosterone-induced hypertension. Thereby, we sought to explore in greater depth the role of aldosterone in mitochondrial biogenesis and fusion/fission processes in hypertension and the associated increases in oxidative stress.

Methods:

Male Wistar rats received aldosterone (1mg/Kg/day) + 1% NaCl as drinking water for 3 weeks.

Results:

Systolic blood pressure was elevated (p<0.05) in aldosterone-treated rats. eNOS and p-eNOSSer1177protein expression was down regulated (p<0.05) and NADPH oxidase subunit p22phox expression was increased (p<0.05) in aldosterone-treated rats. Expression of mitochondrial biogenesis proteins SIRT1, PGC1α, PPARγ, and TFAM decreased (p<0.05) in aldosterone-treated rats. Protein expression of vascular DRP1, OMA1 and S-OPA1 up regulated (p<0.05) in aldosterone-treated rats. MFN1 and L-OPA1 (p<0.05) decreased in aldosterone-treated animals.

Conclusion:

The results showed that, in aldosterone-treated rats, hypertension is likely associated with increased oxidative stress in the aorta and with changes in the regulation of two key mitochondrial processes such as biogenesis and fusion/fission processes. The overall mitochondrial alterations observed in the study may play a role in aldosterone-derived vascular oxidative stress and hypertension.
Asymptotic Relative Efficiencies of the Score and Robust Tests in Genetic Association Studies
Authors: Yuan Ao , Fan Ruzong , Xu Jinfeng , Xue Yuan , Li Qizhai
Published: December 2018

Introduction:

The score statisticZ(θ)and the maximin efficient robust test statisticZMERTare commonly used in genetic association study, but according to our knowledge there is no formal comparison of them.

Methods:

In this report, we compare the asymptotic behavior ofZ(θ)andZMERT, by computing their Asymptotic Relative Efficiencies (AREs) relative to each other. Four commonly used ARE measures, the Pitman ARE, Chernoff ARE, Hodges-Lehmann ARE and the Bahadur ARE are considered. Some modifications of these methods are made to simplify the computations. We found that the Chernoff, Hodges-Lehmann and Bahadur AREs are suitable for our setting.

Results and Conclusion:

Based on our study, the efficiencies of the two test statistic varies for different criterion used, and for different parameter values under the same criterion, so each test has its advantages and dis-advantages according to the criterion used and the parameters involved, which are described in the context. Numerical examples are given to illustrate the use of the two statistics in genetic association study.
STUDENT’S MATHEMATICAL VALUE IN MATHEMATICS LEARNING USING NON-ROUTINE PROBLEM
Authors: Safura Nurul Ain , Aisyah Nyimas , Hiltrimartin Cecil , Indaryanti Indaryanti
Published: December 2018

Abstract: This study aims to determine the ability of students in solving non-routine problems in learning mathematics in high school. The focus of the study is the ability of students in solving non-routine problems that include the value of objectism, value of control, value of mystery, value of progress, value of rationalism, and value of openness. The subject of this study was determined purposively, that was based on the diversity of answers. The selected subject was six students of class X SMA in Palembang. The data were collected using observation, test, and interview which were then analyzed descriptively. The results show that in general the ability of students in solving non-routine problems is dominated by the value of objectism, control, rationalism, and progress. The other two values which did not dominantly appear were mystery and openness. Keywords: mathematical value, non-routine problemNILAI MATEMATIKA (MATHEMATICAL VALUE) SISWA PADA PEMBELAJARAN MATEMATIKA MENGGUNAKAN SOAL NON RUTIN Abstrak: Penelitian ini bertujuan untuk mengetahui kemampuan siswa dalam menyelesaikan soal non rutin pada pembelajaran matematika di SMA. Fokus penelitian adalah kemampuan siswa dalam menyelesaikan soal non rutin yang meliputi nilai objektisme, nilai kontrol, nilai misteri, nilai kemajuan, nilai rasionalisme, dan nilai keterbukaan. Adapun subjek penelitian ini dipilih secara purposive, berdasarkan keberagaman jawaban. Subjek yang terpilih adalah enam orang siswa kelas X SMA di Palembang. Data dikumpulkan menggunakan observasi, tes, dan juga wawancara, yang kemudian di analisis secara deskriptif.  Hasil penelitian menunjukkan bahwa secara umum kemampuan siswa dalam menyelesaikan soal non rutin masih didominasi pada nilai objektisme, nilai kontrol, nilai rasionalisme, dan nilai kemajuan. Dua nilai lain yang tidak dominan muncul adalah nilai misteri dan nilai keterbukaan.Kata Kunci: nilai matematika, soal non rutin
TRANSFORMATIVE EDUCATION AS A DIALECTIC OF INDONESIAN CULTURE AND MODERN CULTURE
Authors: Rochmat Saefur
Published: December 2018

Abstract:Indonesia has being an independent state more than 73 year, but it is not yet a modern state. It is due to a lack of continuity between Indonesian culture (in the forms of local cultures and religions) and modern culture. National culture, in the form of Pancasila state, is not similar to the original Indonesian culture as it is a mix of Indonesian culture and modern culture. This article is to elaborate transformative education which will synergize Indonesian culture and modern culture.This article is a kind of qualitative research, using observation and literature study methods. It focuses on the immaterial aspects of culture, namely supra-structure of both Indonesian culture and the modern one. Curriculum 2013 Revised that discards religious skills from all subjects, except Religious Education and Civic Education, reflects that government has not yet formulated clearly the national education system. National education should be transformative that enables to synergize the Indonesian culture to the modern one. Keywords:Indonesian culture, modern culture, religious skills, Pancasila PENDIDIKAN TRANSFORMATIF SEBAGAI DIALEKTIKA KEBUDAYAAN ASLI DENGAN KEBUDAYAAN MODERN  Abstrak:Setelah merdeka lebih 73 tahun, Indonesia masih belum menjadi negara modern.Hal itu terjadi karena adanya kesenjangan antara kebudayaan lama dengan kebudayaan modern. Kebudayaan nasional dalam bentuk kebudayaan Pancasila tidak sepenuhnya merupakan kelanjutan kebudayaan asli sehingga Indonesia harus melakukan transformasi budaya. Artikel ini akan membahas pendidikan transformatif, yang akan mendialektikakan kebudayaan asli dengan kebudayaan modern.Artikel ini merupakan hasil penelitian kualitatif, yang dilakukan dengan metode observasi dan studi pustaka. Penelitian ditekankan pada aspek immaterial (suprastruktur), yang menjadi fondasi bagi struktur kebudayaan, baik dalam kebudayaan Indonesia maupun kebudayaan modern. Pendidikan transformatif merupakan pendidikan yang mampu mensinergikan suprastruktur kebudayaan asli (kebudayaan daerah dan agama) dengan suprasturktur kebudayanaan modern. Aspek suprastruktur kebudayaan asli tercermin dalam sila ke-1 yang bersifat religius, sedangkan aspek suprastruktur kebudayaan modern tercermin dalam sila ke-2, 3, 4, dan 5 yang sifatnya rasional. Kedua karakteristik ilmu itu harus menyatu dalam materi pelajaran yang diajarkan di sekolah, yang tercermin dalam religious skills. Kata kunci: kebudayaan asli, kebudayaan modern, religious skills, Pancasila
DOES PROBLEM-BASED LEARNING IMPROVE CRITICAL THINKING SKILL?
Authors: Narmaditya Bagus Shandy , Wulandari Dwi , Sakarji Siti Rosnita Binti
Published: December 2018

Abstract: The study aims to understand the implementation of Problem-Based Learning and its impact on critical thinking skills for senior high school students. The study used the lesson study approach that was conducted in four cycles. Each learning activity consisted of identifying topic, presenting the report, and evaluating the Problem-Based Learning. The subject of the study was in a Senior High School in Malang, Indonesia. The level of critical thinking refers to Structure Observed Learning Outcome (SOLO) Taxonomy, consisting of Prestructural, Unistructural, Multistructural, Relational, and Extended Abstract thinking levels. The findings in the learning process show that the students’ critical thinking skills has increased. It is revealed by improving the ability to solve problems and making conclusions through critical thinking processes. The implementation of Problem-Based Learning also encourages students to think critically in the form of questioning, discussing problems and making solutions related to the employment issues, national income and economic growth in Indonesia.  Keywords: Problem-Based Learning, Critical Thinking Skills, Lesson Study APAKAH PROBLEM-BASED LEARNING DAPAT MENINGKATKAN KEMAMPUAN BERPIKIR KRITIS? Abstrak: Penelitian ini bertujuan untuk mengetahui penerapan Problem-Based Learning dan pengaruhnya terhadap kemampuan berpikir kritis pada siswa sekolah menengah atas. Penelitian ini menggunakan pendekatan lesson study yang dilakukan melalui empat siklus. Setiap aktivitas pembelajaran terdiri dari mengindentifikasi permasalahan, mempresentasikan laporan kegiatan, dan mengevaluasi pelaksanaan Problem-Based Learning. Subject penelitian ini dilakukan pada sebuah Sekolah Menengah Atas di Malang, Indonesia. Tingkat kemampuan berpikir kritis siswa dalam penelitian ini mengacu pada taksonomi SOLO (Structure Observed Learning Outcome) yang meliputi prastruktural, Unistruktural, Multistruktural, Relasional, and Extended Abstract. Hasil penelitian ini menunjukkan bahwa selama proses pembelajaran, kemampuan siswa dalam berpikir kritis telah meningkat. Hal ini ditunjukkan dari peningkatan kemampuan menyelesaikan masalah dan membuat kesimpulan melalui proses berpikir kritis. Penerapan Problem-Based Learning juga mendorong siswa memiliki kemampuan berpikir kritis dalam berbagai aktivitas seperti mengajukan pertanyaan, mendiskusikan permasalahan, dan membuat solusi terkait permasalahan pengangguran, pendapatan nasional, pertumbuhan ekonomi di Indonesia. Kata Kunci: Problem-Based Learning, Kemampuan Berpikir Kritis, Lesson Study
NASIONALISME DAN REVOLUSI: PENGALAMAN INDONESIA
Authors: Aman Aman -
Published: December 2018

Abstract Nasionalisme dalam dimensi historisitas dan normativitas, merupakan sebuah penemuan sosial yang paling menakjubkan dalam perjalanan sejarah manusia, paling kurang dalam dasa warsa seratus tahun terakhir. Tidak ada satu pun ruang geografis-sosial di muka bumi yang lepas sepenuhnya dari pengaruh ideologi ini. Tanpa ideology nasionalisme, dinamika  sejarah manusia akan berbeda sama sekali. Berakhirnya Perang Dingin dan semakin merebaknya konsepsi dan arus globalisme (internasionalisme) pada dekade 1990-an hingga sekarang, khususnya dengan adanya teknologi komunikasi dan informasi yang berkembang dengan sangat pesat, tidak dengan serta-merta membawa keruntuhan bagi nasionalisme. Sebaliknya, medan-medan ekspresi konsepsi nasionalisme menjadi semakin intensif dalam berbagai interaksi dan komunikasi sosial, politik, kultur, dan bahkan ekonomi internasional, baik di kalangan negara maju, seperti Amerika Serikat, Jerman, dan Perancis, maupun di kalangan negara Dunia Ketiga, seperti India, China, Malaysia, dan Indonesia. Nasionalisme tetap menjadi payung social-kultur negara-negara manapun untuk mengukuhkan integritasnya.
NASIONALISASI PERUSAHAAN ASING DI JAWA TIMUR 1950-1966
Authors: Darini Ririn , Miftahuddin Miftahuddin
Published: December 2018

Pada awal tahun 1950-an terdapat lebih dari 6000 bekas pegawai sipil kolonial dipertahankan dalam posisi-posisi senior dalam birokrasi Indonesia, banyak yang menggunakan kekuasaan mereka untuk menguntungkan kepentingan-kepentingan Belanda. Oleh karena itu pada awal tahun 1950an, para tokoh Indonesia mulai memikirkan pembangunan ekonomi nasional. Nasionalisme ekonomi diartikan sebagai aspirasi suatu bangsa untuk memiliki atau setidaknya menguasai aset-aset yang dimiliki atau dikuasai oleh bangsa lain dan menjalankan fungsi ekonomi yang dijalankan oleh bangsa lain. Untuk itu, penelitian ini akan melihat latar belakang nasionalisasi perusahaan asing di Indonesia, pelaksanaan nasionalisasi perusahaan asing di Jawa Timur, dan dampak nasionalisasi dalam kehidupan politik, ekonomi, dan sosial. Hasil penelitian menunjukkan, bahwa tindakan nasionalisasi perusahaan asing di Indonesia pada tahun 1950an dilatarbelakangi faktor politik maupun faktor ekonomi.

Kata Kunci: Jawa Timur, Nasionalisasi, dan Perusahaan Asing.