bluuebunny/crossref_metadata_2025 huggingface dataset:
KONTRIBUSI HASIL HUTAN BUKAN KAYU TERHADAP PENDAPATAN MASYARAKAT SEKITAR HUTAN LARANGAN ADAT GHIMBO POTAI KECAMATAN KAMPAR KABUPATEN KAMPAR PROVINSI RIAU
Authors: Sutami Sutami , Mardhiansyah Muhammad , Yoza Defri
Published: May 2022

Ghimbo Potai Banned Indigenous Forest is a prohibited forest that has a variety of wood species and non-timber forest products used by communities around the forest, along with the times, the use of non-timber forest products began to decline. The purpose of this study was to determine the types of non-timber forest products that are used by the community in Ghimbo Potai Banned Indigenous Forest  and to determine the contribution of non-timber forest products to the community income around Ghimbo Potai Banned Indigenous Forest . This research was conducted with a qualitative descriptive method. The number of respondents was 170 respondents from Koto Tibun Village and Pulau Tinggi Village. The result show that Ghimbo Potai Banned Indigenous Forest  still has non-timber forest products that can still be used such as chempedak (Artocarpus integer), petai (Parkia speciosa), long jack (Eurycomma longifolia), rattan (Calamus rotang), rambutan (Nephellium sp.), langsat (Lansium domesticum Corr), tampoi (Beccauera sp.), tempunik (Artocarpus rigidus), durian (Durio zibethinus), jelutong (Dyera costulata), terap (Artocarpus sp.), pulasan (Nephelium mutabile), dogfruit (Archidendron pauciflorum) and the eyebrowed thrush (Turdus obscurus). The contribution of non-timber forest products in Koto Tibun Village was Rp. 596,400,000.00 per year, so the percentage of non-timber forest product revenue to total income was 19.56% and Pulau Tinggi Village no longer takes or utilizes existing non-timber forest products in Ghimbo Potai Banned Indigenous Forest .
PERAN SERTA MASYARAKAT DALAM KONSERVASI HUTAN MANGROVE DI DESA TANJUNG PASIR KECAMATAN TANAH MERAH KABUPATEN INDRAGIRI HILIR
Authors: Agustina Masita , Qomar Nurul , Darlis Viny Volcherina
Published: May 2022

Indragiri Hilir is a district in the southern part of Riau Province, on the east coast of Sumatra Island. Tanjung Pasir is one of the village surrounded by mangrove forest ecosystems, located opposite the Kuala Enok Village. The dominant Tanjung Pasir villagers are ethnic Duano. People meet their daily needs by utilizing mangrove ecosystems as a means of income, good used directly and indirectly. Therefore it is necessary to conduct research on community participation in the conservation of mangrove forest in Tanjung Pasir Village. This research method is descriptive qualitative, data collected through interviews. The result showed that the community was quite involved in the conservation of the Tanjung Pasir village mangrove forest. The form of community participation was by mangrove nurseries and planting.
Heavy Metal Content in Sediment and Hora Shell (Cerithidea obtusa) in Panipahan Waters, Rokan Hilir, Riau
Authors: Wariski Indra , Siregar Yusni Ikhwan , Amin Bintal
Published: May 2022

This research was carried out in March 2021 to analyze the heavy metal content of Pb and Cu in the sediment and flesh of the horn shell (Cerithidea obtusa). Sediment samples and horn shells were taken from the coastal waters of Panipahan, Panipahan Village, and Teluk Pulai Village, Rokan Hilir Regency, Riau Province. The method used in this research is a survey method. Sampling was determined by using purposive sampling at three different stations. The results of this study showed that the metal content of Pb and Cu was highest in sediments around residential areas (44.7150 g/g and 104.4200 g/g), while the horn shell was found in areas far from anthropogenic activities (2.4717 g/g and 8.6617 g/g). Differences in the metal content of Pb and Cu in the sediments were found between stations, while for horn shells there was no difference between stations. The metal content of Pb in the sediment did not show a significant effect (F < 0.05) Pb content in horn shells, as well as Cu. The results of the calculation of the PTWI (Provisional Tolerable Weekly Intake) value indicated that the horn shell in the waters is acceptable for consumption
Inhibition Test of Hot Water Extract of Rhizophora apiculata Leaves Against Edwardsiella tarda Bacteria in-Vitro
Authors: Kurniawan Ronal , Wahyuni Sri , Armando Fitrian
Published: May 2022

One of the plants that have the potential as antibacterial ingredients is Rhizophora apiculata leaf because it contains secondary metabolites, such as tannins, saponins, flavonoids, steroids, and terpenoids. This study aims to find out the inhibition of hot water extract of R. apiculata leaves in inhibiting the growth of Edwardsiella tarda. The research method used is an experimental method which includes sample preparation, extraction, antibacterial activity test using the Kirby-Bauer disc method and applying a Completely Randomized Design (CRD). The doses used were 100% (10000 ppm), 90% (9000 ppm), 80% (8000 ppm), 70% (7000 ppm), 60% (6000 ppm), 50% (5000 ppm), 40% (4000 ppm), 30% (3000 ppm), 20% (2000 ppm), 10% (1000 ppm) and control (Oxytetracycline). The results showed that the hot water extract of R. apiculata leaves at a dose of 1000-10000 ppm gave various inhibitory diameters ranging from 6.25-10.08 mm and the clear zone formed was classified as medium
Growth of Bacteria Bacillus cereus in Liquid Media with Different Protein Sources
Authors: Mukti Pranata Rangga , Feliatra Feliatra , Effendi Irwan
Published: May 2022

The aim of this research was to determine the optimal media composition and incubation time for the growth of Bacillus cereus and B. cereus isolate consortium with other strains isolate. Using an experimental method, which was testing 2 groups of bacterial isolates; B. cereus strain SN7 (isolate N) and bacterial consortium (combination of 5 isolates of B. cereus with different strains). Each group of isolates was grown in sago waste media added with two different protein sources (egg whites and skim milk) and 3 different concentrations in each protein source (8%, 10%, and 12%) with 3 replications in each treatment. Bacterial culture was measured every 6 hours for 24 hours using three methods; total agar plate count, spectrophotometric methods, and bacterial cell biomass methods. There was no significant difference between the growth of these two groups of bacterial isolates. Optimal growth of each isolate was in the sago waste media which was added with egg white but with different concentrations, namely 10% in B. cereus SN7 and 12% in the consortium. B. cereus consortium showed higher growth than B. cereus SN7. The optimal time for bacteria to grow was in the range of 12 to 24 hours.
Growth of Bacteria Bacillus cereus in Liquid Mediums with Different Carbohydrate Sources
Authors: Nengsih Irma Ardila , Feliatra Feliatra , Effendi Irwan
Published: May 2022

Bacteria need a medium to grow Bacillus cereus is a probiotic bacterium. Molasses and tofu liquid waste are one of the wastes that are used as alternative medium, because they are easy to obtain, cheap, and contain nutrients that are high enough in the form of carbohydrates. This study aimed to determine the optimal medium for the growth of these bacteria. This study used a completely randomized factorial design. It consists of three factors, namely the type of waste (molasses + egg albumen and tofu liquid waste + egg albumen), then the combination of isolates (B. cereus SN7 and consortium), and the concentration of liquid waste used for medium growth is (molasses is 1%; 1.5% ; and 2% while tofu liquid waste is 8%; 10%; and 12%). Bacterial cell growth was measured by the Total Plate Count (TPC) method, spectrophotometric method, and biomass, while the incubation period for cell growth was measured every 0, 6, 12, 18, and 24 hours. The results of this study indicated that molasses + egg albumen with a concentration of 1% was the best medium for the growth of B. cereus bacteria along with consortium isolates
Relationship Between Microplastics Abundance and Sediment Organic Content in Dumai Coastal Waters
Authors: Zientika Zientika , Amin Bintal , Yoswaty Dessy
Published: May 2022

Plastics in the environment would eventually be degraded into plastic granules which are called microplastics. In recent years, microplastics have been spread widely not only inland but also in aquatic habitats, where averagely 5% of the plastic produced each year will end up in marine waters. The purpose of this study which was conducted in October to November 2020 was to identify the type and abundance of microplastics in the sediment as well as its possible relationship with the sediment organic matter in Dumai waters. Sediment samples were taken from Dumai coastal waters by using purposive sampling method. Identification of the types and abundance of microplastics as well as the analysis of sediment organic content were carried out in the Laboratory of Chemical Oceanography, Department of Marine Sciences, Universitas Riau. Microplastic and sediment particles were separated using 150 ml saturated NaCl solution. The types of microplastics found are fiber, fragment and films, where fiber was found to be the most commonly found (36.43%), followed by fragments (31.97%) and films (31.60%), respectively. No significant correlation found between microplastic abundance and the sediment organic content in Dumai coastal waters
Ratio of Elements Carbon (C), Nitrogen (N), and Phosphorus (P) At Sediment in Seagrass Ecosystem Nirwana Beach Padang West Sumatera
Authors: Silitonga May Sarah , Nedi Syahril , Zulkifli Zulkifli
Published: May 2022

This research was conducted in November 2020 at Nirwana Beach, Teluk Bayur, Padang City, West Sumatra Province. The organic carbon concentration in the sediments at Nirwana Beach ranges from 1.0320 – 3.03550%, the nitrate content ranges from 0.8599– 0.9577 mg/L, the phosphate 1.8231– 2.7616 mg/L. The C:N:P ratio of sediment is 18.75:1:2.25. The type of sediment found in this study is gravel-sand and seagrass found in the research location was  Thalassia hemprichii with a density of 105 - 312 stands/m2. The correlation between the concentration of organic carbon, nitrate, and phosphate on the density of seagrass species is positive
The Potential of Marine Ecotourism in Pandan Beach, Districts Central Tapanuli, Province of North Sumatera
Authors: Nabila Amelia , Nasution Syafruddin , Siregar Yusni Ikhwan
Published: May 2022

Marine ecotourism is a type of special interest tourism that has marine-related activities, both under the sea and above sea level. Marine ecotourism can be one of the key factors in supporting the protection of cultural values that live in society, sustainability, and the quality of the environment. In tourism development, there are two approaches, namely mass tourism development and sustainable tourism. The study was conducted in February - April 2021 on the Pandan Beach of Central Tapanuli Regency, the Province of North Sumatera. The aims of the study were to determine the marine ecotourism potential and to know the perception of stakeholders. The method used in this study is a survey method, with respondents comprising of local people, tourists, business tourism, and policymakers. Water measuring observed includes water brightness, temperature, salinity, acidity (pH), and the flow velocity carried. The results showed that the tourist attraction at Pandan Beach includes enjoying the panorama, sunset, traditional culinary, sports activity, mangrove and the ecologically at Pandan Beach is white sand with clear waters and have beautiful panorama with lush pine tree vegetation, as well as activities that can be done such as fishing, swimming, boating, and walking around the beach. Tourism Suitability Index values at stations I, II, and III were 96%, 95%, and 71%, respectively. Pandan Beach has the potential as a marine ecotourism area such as natural beauty that is pristine, natural and so exotic
Assessment of accuracy of three different generations of electronic apex locators in different environments of root canal system: An in vitro study
Authors: Rajbhandari Santosh Man , Khanal Sunita , Karmacharya Anu
Published: May 2022

Background: Endodontic treatment encompasses cleaning, shaping, disinfection, and three-dimensional obturation of entire accurate length of root canal system. Hence, accurate determination of working length plays very important role for clinical success of endodontic treatment.
Objectives: To assess the accuracy of three different generations of electronic apex locators (EALs) in different environments of root canal system.
Methods:  A descriptive cross-sectional study was done in 60 single-rooted mandibular premolars for three months from 2021/12/21 to 2021/03/18 at Kantipur Dental College. Non-carious teeth were collected (excluded if more than one canal) by convenience sampling after ethical clearance. Access opening with occlusal reduction of cusp tips were performed. Before, electronic measurement of root canal length, reference length: Actual Length (AL) was recorded. Samples were divided into four groups with different environment (I = dry Canal; II = 3% NaOCl; III = 2% CHX; IV = blood Plasma) with 15 samples each. Electronic measurements were obtained using all three EALs: Rootor (fourth generation), Propex Pixi (fifth generation), and Apex ID (sixth generation). Recorded AL was compared with value obtained with EALs and their differences were tabulated with Microsoft Excel.
Results: Accuracy in working length measurement by Rootor was 80%, 80%, 60%, 53.3%, Propex Pixi was 46.7%, 80%, 86.7%, and 100%  and Apex ID was 100%, 93.3%, 86.7%, 100% in Group I, Group II, Group III, and Group IV respectively of AL.
Conclusion: Accuracy of Rootor was high in dry canal, Propex Pixi in moist environment whereas, Apex ID in both dry canal and moist environment.
Significance of Candida species in patients with coronavirus disease
Authors: Gurung Kishor , Pokhrel Sandeep , Neupane Dhan Raj , Pant Prabesh , Gurung Samjhana
Published: May 2022

Background: Respiratory fungal infection is a severe clinical condition especially in immune-compromised individuals. Secondary fungal infections as complications of severe coronavirus disease 2019 are on the rise. 
Objectives: This study was carried out to isolate the Candida species from coronavirus disease 2019 patients, identify different species of Candida and to show the significance of Candida species in coronavirus disease 2019 patients attending a dedicated hospital for coronavirus disease management.
Methods: A hospital-based descriptive cross-sectional study was done in a period between 2nd Jestha to 23rd Ashad 2077 (16th May to 7th July 2021) in Nepalgunj Medical College, Kohalpur, Banke. The study included 100 Coronavirus disease 2019 patients. Sputum samples were taken and subjected to direct microscopy, cultured onto Sabouraud Dextrose Agar. Candida species were determined by standard microbiological methods. Informed consent was taken prior to participation in study. Data were analysed for simple descriptive analysis using Microsoft Office Excel.
Results: Out of 100 sputum samples, 78 (78%) men and 22 (22%) women were included; Candida species were isolated from 36 (36%) patients. This study shows Candida species isolated higher in male and from 31-60 years of age group. 
Conclusion: We recommend that the investigation and identification of Candida may be routinely followed in the microbiology laboratories.
Cystic partially differentiated nephroblastoma in infant: A case report
Authors: Sah Anil Kumar , Nepal Umesh , Pandey Greta
Published: May 2022

Cystic partially differentiated nephroblastoma is a variant of the multilocular cystic renal tumour, considered as the bridge between cystic nephroma and cystic Wilm's tumour. It usually occurs in children below the age of two years with predominance in male. Histopathology is considered a diagnostic modality. Neoadjuvant chemotherapy and adjuvant radiotherapy may benefit the patient in selected cases. Here, a five-month-old boy who presented with painless gradually increasing right sided abdominal mass is reported. Imaging and fine needle aspiration cytology findings were inconclusive to reach the diagnosis. The histopathology after a radical nephrectomy concluded the diagnosis of cystic partially differentiated nephroblastoma.
Relative position of mandibular foramen for inferior alveolar nerve block in children: A digital panoramic radiographic study
Authors: Upadhyay Sumita , Poudyal Sijan , Mahanta Swagat Kumar , Bali Harleen , Luitel Abhinaya , Niroula Deepa
Published: May 2022

Background: For a successful inferior alveolar nerve block, good knowledge of position of mandibular foramen is imperative.
Objectives: To evaluate the position of mandibular foramen in relation to mandibular occlusal plane and anterior border of ramus in a selected population of children in Nepal using digital panoramic radiographs.
Methods: An analytical cross-sectional study was done after ethical approval in convenient sample of 180 children of 3-13 years in department of Paediatric and Preventive Dentistry, Dhulikhel Hospital from January 2021 to August 2021. Their digital panoramic radiographs were analysed using software Rainbow TM Image Viewer version 1.0.0.0. Mean with standard deviation were calculated for linear measurements taken from mandibular foramen to mandibular occlusal plane and deepest point on the anterior border of ramus. Paired t-test was used to compare measurements between right and left sides. Student t-test was used to evaluate the difference between boys and girls. Pearson correlation was used to observe the correlation of age with the linear measurements.
Results: The mean linear measurements increased along with the increase in age (p <0.05). There was statistically significant difference in linear measurements between the two sides of mandible except in 3-4 years children for mandibular foramen to anterior border of ramus which was not significant (p = 0.090). There was no significant difference in linear measurements between boys and girls.
Conclusion: For inferior alveolar nerve block, the needle should be placed below the occlusal plane in children up to seven years of age and above for higher ages.
Assessment of patient satisfaction after implementing an Enhanced Recovery After Surgery (ERAS) protocol for elective Caesarean sections
Authors: Karki Dilasha , Saha Rachana
Published: May 2022

Background: Enhanced Recovery After Surgery (ERAS) is a multimodal patient centred perioperative care pathway aimed at accelerating patient recovery, improving patient satisfaction, decreasing length of hospital stay, and post-operative complications.
Objectives: To assess patient satisfaction with ERAS protocol in the most common surgical procedure in the world, elective Caesarean Section.
Methods: A descriptive cross-sectional study was carried out in the department of Obstetrics and Gynaecology at Kathmandu Medical College Teaching Hospital (KMCTH) from July 2020 to February 2021 after ethical approval. The study included all pregnant ladies undergoing elective Caesarean section under ERAS protocol by convenient sampling and their satisfaction with the treatment received was recorded using a pre-validated questionnaire at the time of discharge. Data was analysed using SPSS.
Results: A total of 140 patients were enrolled in the study. Majority of the patients considered the introduction of feeding (100, 71.4%) and ambulation (115, 82.1%) to be on time. Seventy-three patients (52.1%) considered themselves fit for discharge on the second post-operative day and 70 (50%) were discharged on the second post-operative day itself which is earlier compared to the hospital protocol of discharge on the third or fifth post-operative day. Most of the women (136, 97.1%) were satisfied with the care they received and 132 (94.3%) of them would prefer to undergo surgery under the ERAS protocol in the future.
Conclusion: Most women were satisfied with the surgical experience and would prefer to undergo surgery under the same protocol in the future.
Determinants of infertility in couples attending maternity hospital
Authors: Rai Snigdha , Malla Bhaba , Upadhyaya Preetam Chandra
Published: May 2022

Background: Infertility is defined as not being able to conceive after one year or longer period of regular unprotected sex. Infertility is an experience that not only strikes at the very core of a couple’s life but also the whole family and society.
Objectives: This study was aimed to establish the various determinants inclusive of diverse male and female factors that are responsible in causing primary or secondary infertility.
Methods: A descriptive cross-sectional study was conducted after ethical approval among 448 couples attending infertility clinic in a Tertiary Care Maternity Hospital from 16th July 2018 to 15th July 2019. Convenient sampling was done. All infertile couples who visited hospital’s infertility clinic during the study period were included in the study. Clinicodemographic and diagnostics details were recorded and analysed using SPSS 20.
Results: Majority of the couples had primary infertility (326, 74.4%). Mean age of the females was 28.08 ± 5.23 years and males was 31 ± 5.7 years. Most of the infertile couples had unexplained infertility followed by female and male factor. Most common female contributing factors was tubal factor (45, 35.16%), followed by ovarian factor (41, 32.2%). Only 104 (23.6%) of the semen analysis had abnormal result among which most common findings was asthenozoospermia.
Conclusion: Primary infertility is more common than secondary infertility. Tubal factor was the most common female contributory factor while asthenozoospermia was predominantly seen among male partners with abnormal semen analysis.
Expression of CD20-specific chimeric antigen receptor (CD20-CAR) on Jurkat T cellsand evaluation its biological activity
Authors:   Biotechnology Center of Ho Chi Minh city, Vo Nguyen Thanh Thao , Chu Dao Xuan Truc ,   Biotechnology Center of Ho Chi Minh city, Huynh Dam Kim Tuyen ,   Biotechnology Center of Ho Chi Minh city, Phung Thi Viet Anh ,   Biotechnology Center of Ho Chi Minh city, Nguyen Dang Quan ,   Biotechnology Center of Ho Chi Minh city
Published: May 2022

CD20 is a potential target for immunotherapy treatments of haematological malignancies due to its specific expression and unique biological property. Over the years, many anti-CD20 monoclonal antibodies (mAbs) have been developed, such as Rituximab, Ibritumomab, Tositumomab, etc., and applied in B cells related to cancer treatments. Recently, a new immunological therapy, namely Chimeric antigen receptor (CAR) T-cell therapy, in which the patient’s T cells are reprogrammed ex vivo with a transgene encoding a CAR in order to active them against the tumour, has emerged as a promising treatment for B-cell malignancies. In this study, the authors generated and expressed two variants of chimeric receptor antigen-specific to CD20 on Jurkat T cells, in which one variant referenced the sequence from the patent (SEQ01) and the other was our own designed sequence (SEQ02). The transient expression after electroporation 24 hours confirmed the presence of mRNA and protein of CD20-CAR in both sequences. Moreover, these chimeric receptors were also detected on the membrane of Jurkat cells using flow cytometer analysis, indicating that the author could successfully transduce and express CD20-CAR in Jurkat cells. Co-culture CD20-Jurkat-CAR-T cells with CD20-expressing Raji B cells show that the generated Jurkat could be activated via their chimeric receptors through increasing the secretion of Interleukin-2 in both sequences. Taken together, our preliminary data suggest that the authors have been able to express the CD20-activating functional transgenic receptor on Jurkat cells, which will be applied for generating CD20-CAR-expressing CD4+/CD8+ T cells.
Research on the one-step regeneration of sugarcane in KK3 variety (Saccharum officinarum L.) in vitro
Authors:   Faculty of Biology - Agricultural Engineering, Hanoi Pedagogical University 2, Phan Thi Thu Hien
Published: May 2022

The research has successfully created the formula for direct regeneration medium of sugarcane variety KK3. In detail, the most suitable medium for direct regeneration from young leaf rolls of sugarcane variety KK3 was RE2 (MS + 5 mg/l α-NAA + 1 mg/l Kinetin), the regeneration rate was 25.27%, the number of shoots formed/1.0 g of young leaf rolls reached 11.56 shoots. The study showed that the position of the young leaf rolls cuttings suitable for direct regeneration was the cuttings located from 2-6 cm away from the growth apex. The shoot regeneration rate reached 25.40%, the regenerating samples were 25.40%, good yield, and a high rate of multiple shoot formation. When using plant cuttings with a thickness of 1 cm, the highest regeneration rate was 25.58%, and the ability to form multiple shoots was high. Pre-cultivation time had a positive effect on the ability to regenerate shoots directly from young leaf coils of sugarcane variety KK3. When conducting pre-cultivation in four days will help increase the regeneration ability of the sugarcane variety, reaching 47.49%. MS medium + 5 mg/l α-NAA + 1 mg/l Kinetin supplemented with 30% coconut water showed the highest regeneration ability, reaching 52.95%, number of shoots reaching 52.33 shoots/1 g of young leaf rolls.
Interaction between surfactants and proteins
Authors: Moreira Leonardo Marmo , Lyon Juliana Pereira
Published: May 2022

Several approaches have been focused on the protein-surfactant interaction. Surfactant-protein interactions are very common in the fields of medicine, chemistry, biology etc. Indeed, many aspects of this interaction have been studied, such as the influence of the aggregation state of the surfactant (monomer, pre-micellar aggregate, micelle, and liposomes) on the protein structure, the properties of the surfactant-protein system, the characterization of the interaction sites on the protein surface, the identification of the intermediate protein conformations etc. The interaction of several types of proteins with the different kind of surfactant can furnish various information to the research of biochemical and biophysical systems, such as the structure-activity relationship of proteins as well as the mechanism of interaction between proteins and amphiphilic molecules. In this context, proteins with prosthetic group are very interesting ones, since the presence of the non-amino acid group can furnishes various information through different instrumental techniques of analysis, acting as a label of all polypeptide chains. The present work analyzes this topic and the potential of these studies.
Doenças transmitidas por alimentos causadas por Salmonella spp. em ovos comerciais
Authors: Rodrigues Tatiana Pacheco
Published: May 2022

A bactéria Salmonella spp. é um dos principais agentes etiológicos de DTA (doenças transmitidas por alimentos) no Brasil e no mundo, nas quais os ovos e os produtos à base de ovos estão envolvidos em diversos surtos. A contaminação dos ovos pode ocorrer em diversas etapas ao longo da cadeia produtiva, desde a obtenção dos pintinhos até o processamento. Portanto, as medidas para minimizar a contaminação destes produtos de origem animal, com a prevenção e o controle da presença de salmonella em ovos é de suma importância para saúde única.
Atualidades no uso de células-tronco para o tratamento de sequelas neurológicas decorrentes da cinomose canina
Authors: Paim Luísa Lovato , Costa Júlia Mariano Peters , Consul Priscilla Machado
Published: May 2022

A cinomose é uma doença infectocontagiosa que acomete animais da ordem Carnívora, sendo o cão o principal reservatório da doença. O Vírus da Cinomose Canina (CVD) causa uma doença de alta morbidade e mortalidade, que pode afetar cães de qualquer idade, raça ou sexo. Quando a resposta imune do indivíduo é insuficiente, o vírus pode persistir por anos nos tecidos, inclusive no sistema nervoso central (SNC). A principal lesão decorrente desta infecção no SNC é a desmielinização e, por isso, mesmo após a recuperação do paciente do quadro agudo da doença, o paciente pode permanecer com sinais clínicos compulsivos. Atualmente são estudadas diversas técnicas para melhorar a qualidade de vida dos animais acometidos com esta infecção, sendo que uma das técnicas em destaque é o uso de células-tronco para o tratamento das sequelas neurológicas da cinomose, que atua por meio da reparação tecidual. Portanto, o objetivo desta revisão de literatura é compilar os principais achados sobre o uso de células-tronco em cães com histórico de cinomose, sua aplicabilidade e eficácia, considerando os avanços recentes em conhecimentos sobre neurorregeneração.
The Usage of Lysosomal Antibodies during the Study of Lysosome Structure and Functions: A Review
Authors: I. Bon Lizaveta
Published: May 2022

Lysosomes are involved in cellular waste degradation and recycling, along with cellular signaling and energy metabolism. Lysosomal storage disorders occur due to the abnormality in genes which are encoding lysosomal proteins. This work aims to emphasize the usage of different lysosomal antibodies during the study of the structure and functions of lysosomes and the investigation of different types of pathological diseases related to lysosomal functions. This may present the characteristics of those antibodies according to a classification that mainly depends on the localization of their targets.
Preliminary Study on the Mechanical Effect of Volatile Components of Artemisia Argyi Fumigation on Virus in the Fencing Effect of Epidemic Prevention
Authors: Zhongdong Liu
Published: May 2022

At present, China has effectively controlled the spread of novel coronavirus COVID-19 by adopting measures such as closure and disinfection. Among them, the traditional method of air mugwort fumigation has played an important role in the prevention and control of epidemics. This method has even been included in the epidemic prevention documents of governments in nine different epidemic areas, which was rare in the past, as shown in Figure 1. This series of events triggered our thoughts on the prevention mechanism of moxa fumigation: to explore the mechanism of the effect of moxa fumigation on the prevention and control of new coronavirus COVID-19, and to make this extremely simple, low-cost and effective method to control the spread of viruses popular in developing and underdeveloped countries on the basis of science.
Pharmacogenomics-Synergistic Strategies Using a Chimerical Peptide for Enhanced Chemotherapy Based on ROS and DNA Nanosystem
Authors: H. Madkour Loutfy
Published: May 2022

Co-delivery of gene and drug for synergistic therapy has provided a promising strategy to cure devastating diseases. The use of genomic predictors of response to cisplatin and pemetrexed can be incorporated into strategies to optimize therapy for advanced solid tumors. Here, a positive feedback strategy was utilized to amplify the concentration of intracellular reactive oxygen species (ROS) and a ROS-triggered self-accelerating drug release nanosystem (defined as T/D@RSMSNs) was demonstrated for enhanced tumor chemotherapy. It was found that in human breast cancer (MCF-7) cells, T/D@RSMSNs could not only release DOX and a-TOS initiatively, but also lead to increased concentration of intracellular ROS, which could be used as new trigger to cut away TK linkage and then in turn facilitate the further release of DOX for enhanced chemotherapy. Standard treatment for advanced non–small-cell lung cancer (NSCLC) includes the use of a platinum-based chemotherapy regimen. This novel ROS triggered self-accelerating drug release nanosystem with remarkably improved therapeutic effects could provide a general strategy to branch out the applications of existing ROS-responsive drug delivery systems (DDSs).
Intraoperative Hemodynamic Fluid Therapy for Immediate- to Highrisk Non-cardiac Surgery: A Narrative Review
Authors: Petsakul Suttasinee , Prathep Sumidtra , Tanasansuttiporn Jutarat , Akaraborworn Osaree
Published: May 2022

The rates of perioperative morbidity and mortality during major surgery have shown a declining trend due to improvements in hemodynamic monitoring and fluid assessment. However, several million surgical procedures involving aged patients and those with multiple comorbidities are performed every year worldwide. Thus, the establishment and constant re-evaluation of appropriate threshold values of perioperative hemodynamic parameters for the management of immediate- to high-risk patients with a narrow safety margin are especially important. Perioperative fluid balance is an important independent risk factor of postoperative morbidity and mortality. In this article, we provide an overview of intraoperative hemodynamic fluid resuscitation and fluid-response monitoring during non-cardiac surgery. We also focus on targets at the macrocirculatory, microcirculatory, and cellular levels.
A New Constitution for Myanmar: Towards Consensus on an Inclusive Federal Democracy
Authors: Bulmer Elliot
Published: May 2022

A NEW CONSTITUTION FOR MYANMAR: Towards Consensus on an Inclusive Federal Democracy provides a study of the constitutional history and trajectory of Myanmar, together with an analysis of the positions of certain key stakeholders in Myanmar with regard to constitutional issues. Areas of constitutional convergence (where the key democratic stakeholders are broadly agreed) and divergence (where they differ) are identified, as are those areas of constitution-building on which the key stakeholders are relatively silent, and that require further attention. This publication thereby provides democratically legitimate political actors in Myanmar, as well as the international community in support of Myanmar’s federal democracy, with a finer understanding of the available range of viable and acceptable constitutional choices.
Структура електронного навчального курсу з англійської мови у Moodle
Authors: Томіліна А. О. , Малоіван М. В.
Published: May 2022

Електронний начальний курс складено з метою залучення ІТ у процес навчання англійській мові у вищій школі. Нами було поставлено завдання: розробити електронний навчальний курс з англійської мови для студентів другого курсу у межах Moodle. Об’єктом дослідження визначено процес навчання студентів англійській мові, предметом дослідження – прийоми використання електронного навчального курсу у межах Moodle у процесі навчання англійській мові. Були залученні наступні методи: вивчення методичної літератури з обраної дисципліни, дидактичне моделювання, педагогічне прогнозування для виявлення результативності застосованої методики навчання англійської мови. Результати дослідження. Електронний курс дисципліни забезпечує високу інтенсивність навчального процесу вивчення англійської мови на базі Moodle. Навчання англійській мові на базі електронного начального курсу забезпечує демократизацію спілкування учасників освітнього простору і розширює коло іншомовного спілкування. Дозованість і регулярність наповнення дидактичним матеріалом у межах електронного курсу формує у студентів дисциплінованість і системність в оволодінні іноземною мовою. Основні висновки. Складений електронний навчальний курс має завершену структуру, орієнтує студента на поступове засвоєння знань, умінь і навичок з дисципліни та систематичний контроль та самоконтроль.
Концепція особистісно діяльнісної освіти у професійній підготовці вчителів іноземної мови
Authors: Штельмах Г. Б.
Published: May 2022

Стаття присвячена проблемі особистісно діяльнісної парадигми в підготовці майбутніх вчителів філологічних спеціальностей. У статті науково обґрунтовані теоретико-методологічні основи організації навчальної діяльності майбутніх педагогів.
System of exercises in formation of foreign students’ cross-cultural competency
Authors: Пальчикова О. О.
Published: May 2022

System of exercises in formation of foreign students’ cross-cultural competency is examined in the article. Types of exercises presented in the article are selected according to developed criteria
Особливості реалізації кроскультурного підходу в процесі викладання іноземних мов
Authors: Пальчикова О. О.
Published: May 2022

У статті визначено сутність понять «підхід», «культура», «кроскультурний підхід», розкрито особливості кроскультурного підходу та його роль у викладанні іноземних мов.
Роль фразеологізмів в усвідомленні мовної картини світу студентами іноземцями під час навчання української мови
Authors: Пальчикова О. О.
Published: May 2022

Проаналізовано роль фразеологізмів в усвідомленні мовної картини світу студентами іноземцями під час навчання української мови. Наголошено, що під час навчання української мови слід ураховувати національно специфічні розбіжності мовних картин світу студентів. Особливу увагу слід приділити формуванню умінь користування фразеологічним фондом мови. Відтак знання фразеологізмів, прислів’їв і приказок дозволяє дослідити зміни в структурі мови та соціально-історичному житті народу – носія, пізнати світовідчуття, світосприйняття та світогляд, властиві лише йому, на основі чого формується характерне уявлення про етнічні групи.
MENTALITY AND EDUCATION: PHILOSOPHICAL AND METHODOLOGICAL ASPECT
Authors: Polezhayev D.V.
Published: May 2022

No abstract.
ANTHROPOLOGY AND HUMANIZATION OF EDUCATION
Authors: Lidak L.V.
Published: May 2022

No abstract.
MAIN TRENDS OF EMOTIONAL RESPONSE TEACHERS IN TENSION PEDAGOGICAL SITUATIONS
Authors: Sergeeva I.V.
Published: May 2022

No abstract.
GOVERNMENT AS AN EFFECTIVE MEANS FORMATION OF PERSONALITY IN CONDITIONS MODERN SOCIETY
Authors: Sharovatova O.P.
Published: May 2022

No abstract.
EDUCATIONAL AND METHODOLOGICAL COMPLEXES IN THE SYSTEM OF EDUCATIONAL PROCESS
Authors: Korzun Z.I.
Published: May 2022

No abstract.
ON THE QUESTION OF THE PRINCIPLES OF THE ORGANIZATION INDIVIDUAL TRAINING IN THE SYSTEM MUSIC TEACHER TRAINING
Authors: Rakityanska L.M.
Published: May 2022

In the article are given modern principles of organization o f the individual approach in the system of personal-oriented education of the teaches of music. 

The author investigates the content of principals of musical and general pedagogic, the ways o f their realization in musical-performing preparing of the teacher of music in the secondary school.

The author reveals the content of musical-performing preparing of the future teacher of music, which is organized on the basic of principals o f professional-oriented education
POLICULTURAL PROFESSIONAL COMPETENCE OF A MODERN TEACHER
Authors: Bilokonna N.I.
Published: May 2022

The problem of the professional competence of a teacher in a context of the future teacher's training for teaching and upbringing activities in the polycultural pedagogical society is considered in the article.
ELECTRONIC DEVICES AS TOOLS IMPLEMENTATION OF PERSONALLY ORIENTED PEOPLE SITUATIONS IN PROFESSIONAL TRAINING MUSIC TEACHER
Authors: Reyzenkind T.Y. , Devyakovich D.A.
Published: May 2022

In the article ways of stimulation of pedagogical situations are considered based on strategy of  individuality developing training with application of computer technologies. Authors describe variants of the organization tasked with the approach in vocational training the teacher of music. Efficiency of use of electronic devices as toolkit of the organization of a individuality-guided situation in formation o f such parameters of  the person o f the teacher as ability to self actualization, a selfestimation, to project new creative tasks comes to light.
QUESTIONS OF PERFORMANCE ANALYSIS IN FORMATION OF CREATIVE PERSONALITY IN LESSONS MUSIC IN SCHOOL
Authors: Martyanova H.M.
Published: May 2022

In the article are considered problems of tasking the approach in conditions of realization of strategy individually focused training. The given approach promotes the formation of such qualities of the person, as possession of original receptions of interpretation of a piece of music, reflections, and receptions of universal thinking.
SIMULATION-ROLE LEARNING AS A PROCESS IMPROVING COMMUNICATIVE CULTURE STUDENTS OF ECONOMIC HIGH SCHOOL
Authors: Vishnevskaya K.H.
Published: May 2022

Те article deals the problems komynikechin culture? It shows factors which influence on the level of skill.
TO THE PROBLEM OF CULTURE FORMATION COMMUNICATION OF FUTURE TEACHERS
Authors: Lysevich O.V.
Published: May 2022

This article reveals the problem of formation of communicative culture in dialogue studying situations.
Від головного редактора
Authors: Тимошик Микола
Published: May 2022

Шановний читачу!

За уважного читання останніх чисел УІП, певне, ви помітили, що традиційна складова змістової частини видання – так зване Передслово – у нас дещо змінилася й стала уподібнюватися класичній передовій. Її змістова домінанта – короткий огляд від часу попереднього випуску вагомих із боку соціальної значущості в інформаційному полі подій, тенденцій, ініціатив, до появи яких причетна журналістика та журналісти, і про які в поточному числі часопису так чи так ідеться в окремих статтях.

На глибоке переконання автора цих рядків, робити це в науковому фаховому журналістикознавчому виданні треба передусім тому, що за переломової доби Української державності актуалізуються будь-які проблиски тенденцій та ініціатив у медійному середовищі. Надважливо не просто помітити, зафіксувати, а й засвідчити переконливу спонуку молодим дослідникам вивчати, узагальнювати, уводити все це до майбутніх досліджень, навчальних програм чи посібників. Цим будемо наближувати реальну журналістську практику, її стандарти, принципи, уроки і чин особистостей в навчально-наукове середовище, де формуються чи гартуються кадри для медійної галузі.
Інформаційна та пропагандистська діяльність Української Народної Республіки (УНР) 1920–1921 років
Authors: Нагорняк Майя
Published: May 2022

В історії українського державотворення надзвичайно вагому роль відіграє буремний період 1920–1921 років, який ознаменувався утвердженням Української Народної Республіки (УНР). Покладено початок розумінню суспільнобудівничої місії ефективних комунікацій, усвідомленню першорядного значення інформаційної і пропагандистської діяльностей в еволюційних процесах становлення України на мапах Європи другого десятиліття ХХ століття. Суспільнополітичні виклики потребували відкритого системного поширення і популяризації як фактів, так і коментарів задля правдивого інформування громадської думки про події внутрішнього й зовнішнього життя, а також із метою недопущення недостовірної інформації про молоду Українську державу у світі. Зважаючи на це, забезпечення української i закордонної спільнот достовірною, повновичерпною інформацією та всеосяжна пропаганда України на всіх рівнях визначали державну політику УНР.

З огляду на зазначене, метою даної розвідки є з’ясувати питання того, в чому полягала інформаційна та пропагандистська діяльність Української Народної Республіки (УНР) 1920–1921 років, за допомогою яких механізмів тогочасним очільникам удавалося забезпечити ефективність як внутрішніх, так і зовнішніх комунікацій. Задля досягнення мети використовувалися такі методи: метод вивчення емпіричного матеріалу (архівних документів), описовий метод, метод узагальнення.

Унаслідок опрацьованих матеріалів Центрального державного архіву вищих органів влади та управління України встановлено, що левову частку інформаційної і пропагандистської роботи було покладено на Міністерство Преси та Пропаганди (тут і надалі всі слова вжито з великої літери відповідно до тогочасних документів — Авт.) на чолі з політичним діячем О. Назаруком, яке було сформовано в уряді В. Чехівського. В межах Міністерства діяв спеціальний відділ, який опікувався інформуванням української еміграції на території Польщі про боротьбу народу Української Народної Республіки за свої права та з ворожим для нього впливом більшовицької росії. Після звільнення України від влади більшовиків гостро постало питання щодо налагодження телеграфного зв’язку з різними місцевостями держави, з іншими країнами, через що урядовці працювали над відбудовою на терені України державної радіотелеграфної сітки.

Пошуки уряду УНР шляхів установлення комунікацій усередині країни та поза її межами, здійснення інформаційної та пропагандистської діяльностей мають неоціненне значення для історії країни, що засвідчує прагнення очільників і пересічних громадян будувати міцну й потужну Українську державу.
Типові гендерні образи літніх людей в українських серіалах
Authors: Коваль Анастасія
Published: May 2022

Зазвичай, чоловіки та жінки поважного віку не показані активними учасниками різних соціальних подій, а є пасивними персонажами. Водночас, слід розуміти, що літні люди колись були молодими, а, отже, – могли бути більш включеними у медійний простір. Особливості змін у медійній репрезентації гендерних образів молодих і дорослих людей у літніх людей досі ґрунтовно не вивчені, що зумовлює актуальність дослідження.

Метою дослідження є визначення особливостей типових гендерних образів літніх людей в українських серіалах.

Методи дослідження: теоретичне обґрунтування вікових змін у типових гендерно-стереотипних образах; дискурс-аналіз жіночих та чоловічих образів літніх людей-персонажів серіалів. Також були використані методи синтезу, індукції та дедукції.

Результати дослідження показали, що вагомим фактором у тому, як літні люди сприймають старість, можуть бути медійні образи, із якими вони себе порівнюють. Засновані на стереотипах, медійні образи літніх людей або не мають нічого спільного із справжнім життям, або вказують на ті особливості, про які люди похилого віку не хотіли б згадувати (погіршення здоров’я, негативні зміни у способі життя, вимушена відмова від певних занять тощо).

Медійні образи, що ґрунтуються на стереотипах, зазвичай звертаються до емоцій, а не до раціонального. Разом з тим, типові образи літніх людей, як правило, з’являються у медіа для того, щоб служити контрастом для молодих людей і у той чи той спосіб допомагати розкриватися їм перед реципієнтом. За невеликим винятком, вони є не самостійними, а невіддільними від медійної ситуації. Іншим сценарієм у медіа є ігнорування або заперечення старості як соціально-економічного і тілесного стану. Соціокультурні стандарти диктують аудиторії, за яких умов бути літньою людиною допустимо, а за яких – ні. За великим рахунком, серед типових гендерних образів літніх людей складно знайти позитивний образ літньої людини, яка не відповідала б цим вимогам.