bluuebunny/crossref_metadata_2025 huggingface dataset:
PELATIHAN PENULISAN KARYA ILMIAH DAN PENELITIAN TINDAKAN KELAS BAGI GURU-GURU SEKECAMATAN GOLEWA BARAT
Authors: Awe Ermelinda Yosefa , Lawe Yosefina Uge , Wau Maria Patrisia , Kaka Pelipus Wungo
Published: January 2021

Pengabdian ini bertujuan meningkatkan pemahaman guru mengenai Penelitian Tindakan Kelas serta menghasilkan artikel ilmiah dari hasil PTK/PTS. Tujuan lainnya adalah membantu para guru dalam kenaikan jabatannya yang selama ini mengalami kendala karena belum optimal dalam melaksanakan Penelitian Tindakan Kelas. Target kegiatan Pengabdian ini selama 8 bulan Sejak Bulan Pebruari 2020 sampai dengan Bulan Oktober 2020, untuk semua Guru di Kecamatan Golewa Barat. Untuk kegiatan tahap Awal yaitu sejak Bulan Pebruari hingga Maret 2020 ini dilakukan di SDI Turekisa. Tahap selanjutnya akan dilaksanakan di SD lainnya. Kegiatan ini   dilakukan oleh Tim dosen Prodi PGSD bekerjasama dengan Koordinator Wilayah Kecamatan Golewa Barat, Kepala Sekolah, dan Para guru se-kecamatan Golewa Barat. Metode  pelatihan  dengan ceramah dan latihan/simulasi. Pendekatan yang digunakan yaitu pendekatan personal dalam setiap latihan, sehingga diharapkan semua guru dapat membuat laporan hasil Penelitian Tindakan Kelas dan dapat menyusun artikel ilmiah. Pelatihan dinilai efektif karena peserta sudah bisa memahami dan mampu membuat Laporan Penelitian dan Artikel Ilmiah. Manfaat Pengabdian ini membantu guru – guru SDI Turekisa dalam menyusun laporan Penelitian Tindakan Kelas yang berkualitas agar dapat dipublikasikan di Jurnal Ilmiah yang merupakan salah satu sarat untuk peningkatan profesionalisme guru.
PELATIHAN KURIKULUM 2013 GURU SEKOLAH DASAR DI SDI FATUKOAN KECAMATAN RINHAT KABUPATEN MALAKA
Authors: Nuriyah  , Khasna Fenny Tanalinal , Akbari Ummu Fajariyah , Kurniawan Budi , Uslan  , Sunimbar
Published: January 2021

Tujuan pelatihan kurikulum 2013 bagi guru SDI Fatukoan ini diharapkan dapat meningkatkan kemampuan guru tentang: (1) model pembelajaran dalam kurikulum 2013; (2) strategi dan pendekatan model pembelajaran dalam implementasi kurikulum 2013; (3) memaparkan materi tentang penguatan pengembangan soal diagnostik; (4) materi tentang   penyusunan Rencana Pelaksanaan Pembelajaran (RPP); (5) tanya jawab tentang materi yang telah disampaikan   terkait Kurikulum 2013 (6) menyusun perangkat pembelajaran. Pelaksanaan kegiatan pengabdian melalui pelatihan kurikulum 2013 berjalan sesuai dengan program yang telah direncanakan. Metode pelaksanaan yang digunakan dalam kegiatan pengabdian masyarakat ini dibagi menjadi 4 (empat) tahapan meliputi (1) observasi awal daerah kegiatan (2) pemetaan masalah (3) sosialisasi kegiatan (4) penyelenggaraan pelatihan dengan melibatkan guru-guru SDI Fatukoan,dan dosen Prodi PGSD Universitas Muhammadiyah Kupang. Outcome yang diperoleh dari kegiatan ini adalah adanya pemahaman guru-guru tentang implementasi kurikulum 2013 serta pengembangan soal diagnostik serta media pembelajaran.
PENGEMBANGAN SISTEM INFORMASI E-LEARNING MENDUKUNG PROSES PEMBELAJARAN JARAK JAUH
Authors: Ambara Made Pradnyana
Published: January 2021

Pada saat pandemi covid-19 seperti ini, mengakibatkan proses pembelajaran tatap muka langsung di kelas tidak mungkin dilakukan. Maka sangat perlu dibuatkan sistem pembelajaran jarak jauh atau sistem daring. Saat ini ada beberapa aplikasi pembelajaran daring yang dapat digunakan secara grafis, tetapi memiliki kelemahan pada manajamen jadwal, absensi dan media komunikasi. Dari permasalahan tersebut perlu dibuatkan sistem elearning yang secara khusus dimiliki oleh lembaga pendidikan untuk membantu proses pembelajaran online yang efektif dan efesien pada masa pandemi seperti saat ini. Metode penelitian sistem menggunakan alur kerja model waterfall classic yang dimulai dari analisis data, desain sistem, pengkodean serta pengujian. Pada proses pengembangan sistem elearning akan menggunakan bahasa pemrograman PHP Codeigniter berbasis web responsive. PHP Codeigniter akan membagai konsep pengkodean sistem menjadi tiga bagian yaitu model, view dan controller. Pembagian pengkodean ini akan memudahkan didalam implementasi dan penanganan error kalau terjadi kesalahan. Pengujian sistem menggunakan metode black box testing untuk menguji fungsional sistem sehingga menghasilkan sistem yang bekerja dengan baik. Hasil penelitian sistem elearning menghasilkan berbagai fitur seperti manajemen jadwal pembelajaran, pemberian materi serta tugas, absensi peserta didik maupun pendidik, dan media komunikasi chat online. Semua fitur ini akan medukung proses pembelajaran jarak jauh peserta didik sehingga tujuan pembelajaran dimasa pandemi covid-19 dapat tercapai dengan baik.
TINJAUAN PEMBELAJARAN VISUAL EKSPRESIF DALAM PROGRAM PENDIDIKAN INKLUSIF
Authors: Kencana Dian , Supriatna Mamat , Yudha Eka Sakti
Published: January 2021

Artikel ini diarahkan untuk menjawab tiga permasalahan, yaitu pengertian, unsur dan kegunaan pembelajaran visual ekspresif dalam program pendidikan inklusif yang berdasarkan hasil studi pustaka tentang Dalam mengkaji tiga persoalan tersebut, penulis menggunakan metode kajian pustaka dari beberapa sumber yang merupakan hasil penelitian baik dari buku teks, jurnal maupun artikel, melalui tahapan: 1) Menelaah karya-karya ilmiah hasil penelitian sebelumnya yang terkait. 2) Mengklasifikasikan atau mengelompokkan konsep-konsep terhadap bahan-bahan bacaan. 3) Mendeskripsikan ulang dalam bentuk analisis terhadap karya ilmiah sebelumnya yang relevan 4) Menyajikan dalam bentuk tabel atau matriks 5) Mengambil saripati. Kegunaan Temuan penelitian ini adalah model hipotetik tentang pembelajaran seni rupa visual ekspresif dalam program pendidikan inklusif, yaitu siswa regular dan siswa disabilitas belajar bersama, berekspresi, berkreasi, berapresiasi dan memiliki makna dalam kehidupan sehari-hari tidak hanya dalam bentuk pengetahuan (konsepsi) dan keterampilan (ekspresi), melainkan memiliki makna yang dalam berupa sikap (apresiasi).
PENILAIAN PELAKSANAAN K-13 DI SEKOLAH DASAR
Authors: Muh Abdul Syahril , Suhada Farhan , Uslan
Published: January 2021

Tujuan dari penilaian ini adalah untuk mengevaluasi dan memperoleh informasi untuk menjelaskan bagaimana efektivitas pelaksanaan kurikulum 2013, serta masalah-masalah yang dapat mempengaruhi efektivitas pelaksanaan Kurikulum 2013. Penilaian ini menggunakan metode kualitatif evaluatif, menganalisis dengan countenance atau STAKE melalui tiga komponen inti yaitu: evaluasi antecedents, transaction, outcomes. Metode pengumpulan data melalui observasi, wawancara dan studi dokumentasi. Data diverifikasi melalui proses trianggulasi. Dari data yang diperoleh, pertama evaluasi antecedents mengenai system rekrutmen siswa, masalah sosial ekonomi orang tua siswa dan penyusunan dokumen kurikulum 2013. Penyusunan dokumen kurikulum 2013 sudah sesuai, namun belum maksimal dalam penerapan karena terkendala SDM guru dalam memahami dokumen kurikulum 2013, sehingga berimbas pada tidak efektifnya manajemen pelayanan penerimaan calon siswa dan solusi guru dalam menghadapi anak yang social ekonomi orang tuanya kurang baik.  Kedua Evaluasi transaction meliputi aspek minat dan motivasi guru yang mengajar, penyesuaian rencana pembelajaran berdasarkan Kurikulum 2013, penilaian berbasis kelas, kegiatan Ekstrakurikuler dan pengembangan diri, hasil perolehan data menunjukan aktifitas dalam pembelajaran siswa sudah menekankan system pembelajaran aktif namun pemahaman guru terkait kurikulum 2013 belum efektif sampai pada pelaksanaan dalam proses pembelajaran, penerapan pembelajaran tematik integratif berbasis saintifik juga belum maksimal. Pengembangan kegiatan ekstrakurikuler masih terkendala dengan kesiapan para guru. Ketiga Evaluasi outcomes meliputi aspek pencapaian kompetensi kognitif, psikomotor dan afektif berdasarkan Kurikulum 2013. Pencapaian kompetensi siswa belum maksimal karena kesiapan guru dalam merencanakan, melaksanakan sampai pada penilaian belum dilaksankan dengan baik sesuai dokumen kurikulum 2013.
PREDICTION OF OOCYTE OUTPUT: How can we maximize the oocyte retrieving from follicles in Controlled Ovarian Hyperstimulation cycles?
Authors: DİKBAŞ Levent , MAMMADLİ Güler , ŞÜKÜR Y. Emre , ATABEKOĞLU Cem , AYTAÇ Ruşen , BERKER Bülent , SONMEZER Murat , ÖZMEN Batuhan
Published: January 2021

PREDICTION OF OOCYTE OUTPUT: How can we maximize the oocyte retrieving from follicles in Controlled Ovarian Hyperstimulation cycles? Abstract Aim: We designed our study with the purpose of determining which variables should be used to predict oocyte output, to increase the number of collected oocytes and the success rate of IVF. Materials and Method: A total of 412 infertile patients admitted to the IVF center of a tertiary university hospital between the years 2016 and 2018 were evaluated retrospectively. The number of oocytes obtained by OPU from the follicles as the result of COH was grouped in percentiles. The variables effective on oocyte output were analyzed in the groups, and tests to predict acquisition of the maximal number of oocytes were tried to be determined. Results: When we investigated according to the oocyte/≥ 14 mm follicle ratios, we determined that 10.2% of the patients were in the ≤ 30% group, whereas 4.1% of them were in the group of 31-40 %. 6.6% of the patients were in the group of 41-50 %, 2.9% in the group of 51-60%, 5.6% in the group of 61-70 %, 8% in the group of 71-80%, 4.9% in the group of 81-90 %, and 57.8% in the group of 91-100 %. According to the results of our study, the variables effective on the oocyte/≥14 mm follicle ratio were the patient’s age, basal FSH value (cutoff 9.5mIU/mL, sensitivity 0.706, specificity 0.621, p=0.001), basal LH (cutoff 5.5mIU/mL, sensitivity 0.640 specificity 0.690, p
A common typology for ecosystem characteristics and ecosystem condition variables
Authors: Czúcz Bálint , Keith Heather , Driver Amanda , Jackson Bethanna , Nicholson Emily , Maes Joachim
Published: January 2021

The UN System of Environmental-Economic Accounting Experimental Ecosystem Accounting (SEEA EEA) aims at regular and standardised stocktaking on the extent of ecosystems, their condition and the services they provide to society. Recording the condition of ecosystems is one of the most complex pieces in this exercise, needing to be supported by robust and consistent guidelines. SEEA EEA defines the condition of an ecosystem as its overall quality, measured in terms of quantitative metrics describing both abiotic and biotic characteristics. The main objective of this paper is to propose a simple universal classification (typology) for these ecosystem condition characteristics and metrics, based on long standing ecological concepts and traditions.

The proposed SEEA EEA Ecosystem Condition Typology (SEEA ECT) is a hierarchical classification consisting of six classes grouped into three main groups (abiotic, biotic and landscape-level ecosystem characteristics). In order to facilitate practical applications, SEEA ECT is cross-linked to the most relevant existing typologies for ecosystem characteristics currently used for other purposes. To ensure clarity and practicality, we identified potential overlaps between classes and also identified the most important groups of ‘ancillary data’ that should not be considered as ecosystem condition characteristics. We consider that this new typology for ecosystem condition will create a meaningful reporting structure for ecosystem condition accounts, thus facilitating its standardisation and broad application.
Parménide, fragment 2 DK : du lexique de l’agir au lexique de la connaissance
Authors: Stella Fabio
Published: January 2021

Cet article se propose de montrer que le lexique utilisé par Parménide dans le fragment 2 DK est pour la plupart tiré d’un vocabulaire déjà homérique, tout à fait « pratique », dont il conserve la cohérence logico-syntactique originelle. La transformation de ce « lexique de l’agir » en « lexique de la connaissance », que Parménide met en œuvre, n’est pas réalisée par une resémantisation de chacun des mots, mais en changeant, grâce à une réflexion métalinguistique sur le texte homérique, le niveau d’abstraction de l’objet du discours, l’ἐόν.
El Paisaje religioso de Pax Iulia (Beja) durante el Alto Imperio romano
Authors: Carlos López-Gómez José
Published: January 2021

Cet article mène une analyse des manifestations religieuses dans la cité de Pax Iulia (Beja) sous le Haut Empire. L’étude porte notamment sur une série de monuments honorifiques du i er siècle après J.-C. en lien avec les sacerdoces du culte dynastique, sur les vestiges d’un temple monumental situé au front du forum et sur un ensemble de quatre épigraphes datés entre le milieu du ii e siècle et le début du iii e siècle qui furent respectivement dédiées à Isis, Mithra, Mater Magna et Bona Dea . L’article analyse donc les particularités des dieux documentés et de leurs fidèles afin de comprendre comment la ville a été prématurément intégrée dans les courants religieux de l’État au début du Principat, ainsi que dans les nouvelles formes de culte qui ont pénétré dans la ville tout au long du deuxième siècle, ce qui a sans doute facilité la participation de toutes les couches sociales au système civico-religieux.
Encadrement des loyers à Paris : les logements à petites pièces plus contraints que les autres
Authors: Malard Louis , Poulhes Mathilde
Published: January 2021

En août 2015, la ville de Paris a renforcé son dispositif d’encadrement des loyers. Les nouveaux loyers ne devaient pas dépasser un certain plafond, défini comme le loyer au mètre carré médian par catégorie (nombre de pièces, grand quartier et époque de construction) majoré de 20 %. Cet article analyse l’impact de ce nouveau dispositif. On montre que l’encadrement n’a été que partiellement respecté : 20 % des loyers se situent au-dessus des plafonds après août 2015. On démontre ensuite que le dispositif d’encadrement est distorsif. Le calcul des plafonds est distinct par nombre de pièces mais ne tient pas compte du fait que des logements disposant du même nombre de pièces peuvent avoir des surfaces très différentes. Ainsi, les logements à petite surface par pièce (ou logements à petites pièces) sont plus contraints par les plafonds. En conséquence, seuls les loyers de ces logements diminuent après la mise en place de l’encadrement.
Quand le souverainisme l’emporte
Authors: Faure Samuel B. H.
Published: January 2021

Cet article explique la structuration du capitalisme français de la défense, à partir de l’étude de l’acquisition par l’État de l’avion de combat Rafale marine en 1988. Ce débouché décisionnel s’explique par la victoire de l’« association souverainiste » sur l’« association libérale » conditionnée par des relations interpersonnelles plus denses à l’échelon politique. L’association souverainiste regroupe des élites civiles et militaires hétérogènes autour d’un programme d’action publique consistant à défendre le territoire national pour produire un avion militaire, plutôt que de réduire les coûts budgétaires en l’important des États-Unis. S’appuyant sur 89 entretiens semi-directifs, le capitalisme français de la défense est analysé à partir de l’approche programmatique qui s’inscrit en sociologie de l’action publique.
Les gardiens des politiques de santé face à la réforme Obama
Authors: Genieys William , Darviche Mohammad-Saïd , Epperson Brent
Published: January 2021

L’étude de la réforme de l’assurance maladie aux États-Unis durant les années 1990 et 2000 montre que loin de disparaître, l’influence des élites de l’État fédéral a été reconfigurée. À l’image des custodians of policy de Philip Selznick, de petits groupes d’élites professionnalisés durablement au cœur des pouvoirs exécutif et législatif ont acquis une expertise stratégique dans certains secteurs de politique. Comme leurs homologues français, les élites des politiques de santé étasuniennes se sont posées en gardiens des politiques de santé en adaptant l’impératif du contrôle des coûts à un héritage historique, institutionnel et politique défavorable à une réforme alignant le système d’assurance maladie sur le modèle des autres démocraties occidentales. C’est au prix de ce « provincialisme » et de la recherche invétérée d’un arrangement politique que la réforme Obama a pu aboutir à une évolution du système d’assurance maladie qui, à défaut d’être systémique, n’en est pas moins la plus importante depuis les années 1960.
Théorie des courants multiples et systèmes politiques consensuels
Authors: Bocquet Nicolas
Published: January 2021

Cet article mobilise un modèle analytique original basé sur la théorie des courants de Kingdon pour analyser quatre processus de mise à l’agenda bruxellois issus des secteurs de la mobilité, de la santé et de la sécurité. Méthodologiquement, il combine process tracing et comparaisons qualitatives en s’appuyant sur une triangulation des sources afin de répondre à la question de recherche suivante : dans quelle mesure compléter la théorie des courants par l’apport de variables propres aux systèmes consensuels permet-il d’accroître la compréhension du processus de mise à l’agenda bruxellois conduisant à l’adoption ou au rejet des solutions des entrepreneurs ? Nos résultats démontrent que le modèle de Kingdon offre une compréhension importante, quoique incomplète des processus étudiés. Dès lors, cet article illustre comment la théorie des courants peut être complétée afin de dépasser ses insuffisances relatives aux systèmes consensuels (fédéraux) et ainsi accroître son pouvoir explicatif de la mise à l’agenda dans ce type de contextes.
L’innovation produit dans la pme de service de haute technologie : le rôle clé de la communauté de pratique
Authors: Dokou Gérard Akrikpan Kokou , Lemoine Sylvie
Published: January 2021

Cet article tente de répondre à la question de recherche suivante : « de quelles manières une communauté de pratique favorise-t-elle l’innovation produit dans le cadre d’une PME de service de haute technologie ? » Aussi, nous avons défini ce qu’est une communauté de pratique puis cerné son processus de création, son développement ainsi que les dimensions de son impact au sein des entreprises. L’étude d’un cas centrée sur une enquête qualitative exploratoire a mis en évidence plusieurs dimensions. Les plus significatives (au sens des tests de Khi2 associés aux verbatims) concernent l’engagement mutuel des membres de la communauté de pratique en termes de construction et de partage des connaissances, la structuration d’une volonté commune, ainsi que la constitution de ressources et des outils communs. Ces mêmes dimensions correspondantes aux trois hypothèses définies à partir de la littérature fournissent de nouvelles perspectives sur l'innovation produit dans les PME
Les systèmes de sante face à la pandémie de COVID-19 : surmonter ferveur, optimisme et négligence
Authors: Ane Mohamed , Callens Stéphane , Traoré Moussa Khoré
Published: January 2021

La pandémie de COVID-19 a parfois infirmé, parfois confirmé les évaluations initiales de l’Organisation Mondiale de la Santé des capacités des systèmes de santé à faire face à ce choc. Ces évaluations initiales sont le plus souvent basées sur des caractéristiques de l’offre de soins, et des insuffisances plus ou moins prononcées de celle-ci : manque de personnel formé, segmentation de la population, ou trop forte prééminence des plateaux techniques dans le système de santé. L’explication des écarts constatés entre les classements des systèmes de santé dans le monde et celui de leurs performances mettent en avant seulement certains de ces travers et font appel à des éléments de contexte et de déroulé de la crise sanitaire. L’économie comportementale dans un contexte dynamique d’apprentissage collectif permet de recomposer une vision synthétique des systèmes de santé et de la médecine de crise. Cette approche souligne en particulier des formations volontaires de rigidité (la Ferveur), et formule l’hypothèse d’une inversion des biais au cours de la crise, des sous-évaluations des facteurs clefs de la pandémie (l’Optimisme) en début de crise à des surévaluations passives (la Négligence).
Les relations France-Algérie et le soulèvement du Hirak
Authors: Le Saout Didier
Published: January 2021

Comment le soulèvement populaire de 2019 interagit-il avec les relations qu’entretiennent la France et l’Algérie ? Résultat d’une enquête sur les lieux de la protestation du Hirak à Paris, cet article présente les jeux et enjeux des diplomaties algérienne et française dans leurs constructions concurrentielles des émotions de colère, de sympathie et de culpabilité, pour interroger ensuite ces représentations officielles dans leur rapport aux émotions populaires partagées par les contestataires.
Que peut-on enseigner ou espérer de l’économie de communion ?
Authors: Tchouassi Gérard
Published: January 2021

L’objectif de cette communication est de comprendre les fondements de l’économie de communion en science sociale et de développer les espérances pratiques des entreprises du secteur de l’économie de communion. Une des avancées de l’économie de communion aujourd’hui l’économie d’affection. L’économie d’affection connaît un regain d’intérêt au niveau scientifique à la fois sur le plan philosophique, neurobiologique, psychologique, sociologique, économique, psychanalytique, ou même politique (Petit, 2009). Pratiquement, les entreprises d’économie de communion exercent leur activité sur le marché et cherchent à réaliser des profits comme les entreprises classiques, mais leur spécificité consiste à donner et à partager une grande partie de leurs profits.
Soigner le mal par le mal : recherche-action sur la technique de l’inoculation pour limiter les résistances à un projet TI
Authors: Bou Saba Peter , Meissonier Régis
Published: January 2021

La littérature académique propose un large éventail de méthodes de gestion du changement visant à identifier et réduire les résistances liées aux projets TI. Alors qu’en psychologie et sociologie, l’originalité de la méthode de l’inoculation a su séduire chercheurs comme praticiens, celle-ci n’a été que peu testée dans le domaine des systèmes d’information. Elle postule que de la même manière qu’un individu peut être vacciné contre un virus, il peut également s’autoprémunir d’influences négatives en s’exposant aux arguments avancés par les détracteurs du projet. La réfutation, à cet effet, consiste à fournir des arguments à l’individu pour l’aider à soutenir son attitude et à être capable de rejeter d’autres contre-argumentations à venir. Cette recherche dévoile les résultats d’une recherche-action menée pendant 3 ans auprès d’une société de conseil au sein de laquelle l’implémentation d’un système d’aide à la décision a été associée à de forts comportements de résistance face auxquels la technique de l’inoculation a été expérimentée pour en limiter les effets. Les résultats tendent à confirmer la contribution de ladite méthode sur la préservation des attitudes positives des partisans avec un effet « boomerang » relatif sur les détracteurs.
Existence of $ \mathcal{D}- $pullback attractor for an infinite dimensional dynamical system
Authors: Yebdri Mustapha
Published: January 2021

At the very beginning of the theory of finite dynamical systems, it was discovered that some relatively simple systems, even of ordinary differential equations, can generate very complicated (chaotic) behaviors. Furthermore these systems are extremely sensitive to perturbations, in the sense that trajectories with close but different initial data may diverge exponentially. Very often, the trajectories of such chaotic systems are localized, up to some transient process, in some subset of the phase space, the so-called strange attractors. Such subset have a very complicated geometric structure. They accumulate the nontrivial dynamics of the system.

For a distributed system, whose time evolution is usually governed by partial differential equations (PDEs), the phase space X is (a subset of) an infinite dimensional function space. We will thus speak of infinite dimensional dynamical systems. Since the global existence and uniqueness of solutions has been proven for a large class of PDEs arising from different domains as Mechanics and Physics, it is therefore natural to investigate whether the features, in particular the notion of attractor, obtained for dynamical systems generated by systems of ODEs generalizes to systems of PDEs.

In this paper we give a positive aftermath by proving the existence of pullback \begin{document}$ \mathcal{D} $\end{document}-attractor. The key point is to find a bounded family of pullback \begin{document}$ \mathcal{D} $\end{document}-absorbing sets then we apply the decomposition techniques and a method used in previous works to verify the pullback \begin{document}$ w $\end{document}-\begin{document}$ \mathcal{D} $\end{document}-limit compactness. It is based on the concept of the Kuratowski measure of noncompactness of a bounded set as well as some new estimates of the equicontinuity of the solutions.
Analysis of an age-structured model for HIV-TB co-infection
Authors: Guo Zhong-Kai , Huo Hai-Feng , Xiang Hong
Published: January 2021

According to the report of the WHO, there is a strong relationship between AIDS and tuberculosis (TB). Therefore, it is very important to study how to control TB in the context of the global AIDS epidemic. In this paper, we establish an age structured mathematical model of HIV-TB co-infection to study the transmission dynamics of this co-infection, and consider awareness in the modeling. We give the basic reproduction numbers for each of the two diseases and find four equilibria, namely, disease-free equilibrium, TB-free equilibrium, HIV-free equilibrium and endemic disease equilibrium. Then we discuss the local stability of the equilibria according to the range of values of the two basic reproduction numbers, and find the endemic equilibrium is unstable. We also discuss the global stability of the disease-free equilibrium and the TB-free equilibrium. Based on the new HIV-positive cases and TB cases data in China, the best-fit parameter values and initial values of the model are identified by the MCMC algorithm. Then we perform uncertainty and sensitivity analysis to identify the parameters that have significant impact on the basic reproduction number \begin{document}$ \mathcal{R}_{T} $\end{document}. Finally, combined with the established model, we give some measures that may help China achieve the goal of WHO of reducing the incidence of TB by 80% by 2030 compared to 2015.
Die letzten Tage der letzten Tage der Menschheit in der Fackel
Authors: Stieg Gerald
Published: January 2021

Die letzten Kriegsfackeln von Oktober und November 1918 konzentrieren Kraus’ satirische Attacken auf das in seinen Augen widernatürliche und verlogene Bündnis zwischen Österreich-Ungarn und Deutschland. Seine zentrale Methode ist das Zitat, das sich im moralisch-juridischen Raum der Fackel selbst richtet. Viele Glossen bieten vorbereitendes Material für Die letzten Tage der Menschheit, aber Kraus druckt auch bereits fertiggestellte Teile aus der Tragödie ab (die Hyänenszene aus der „Letzten Nacht“ und das „Lied des Alldeutschen“). Alle Themen stehen unter dem Grundvorwurf der „nackten Fälschung der Tatsachen“ durch die politische und journalistische Phrase, die vor das unerbittliche Sprachgericht der Fackel gestellt wird. Exemplarisch wird das am Beispiel des Zweibunds, der Sixtus-Affäre, der Ernährungsfrage und an einigen Eingriffen der Zensur gezeigt. In den Auszügen aus der Tragödie zeigt sich der Satiriker einerseits als Erbe der prophetisch-apokalyptischen Tradition, andererseits als Analytiker einer tollgewordenen Phraseologie.
„Das könnte man gesellschaftlich so sagen, aber es wäre weiter nichts als eine vertuschende Redeweise“ (Theodor, 1. Akt, 12. Szene)
Authors: Wolf Monika
Published: January 2021

Der Beitrag analysiert einen literarischen Text mit sprachwissenschaftlichen Methoden. Er liefert eine mikrostrukturelle Beschreibung des Gesprächsverhaltens in einer hierarchisch strukturierten Gesellschaft im alten Österreich anhand einer zentralen Szene in Hofmannsthals Lustspiel Der Unbestechliche. Dabei wird untersucht, mit welchen sprachlichen Mitteln die Figuren ihre Emotionen verbalisieren. Die soziale Stellung der einzelnen Figuren in der untergehenden Habsburger Monarchie wirkt sich deutlich auf die sprachlichen Ausdrücke und ihre Funktionen im Text aus. Mit anderen Worten: Die Emotionalität ist ein wesentlicher Teil der Dialoge in diesem Drama und äußert sich auf allen sprachlichen Ebenen, wobei sie vor allem den Zweck der sozialen Positionierung hat. Daher eignet sich dieses Stücks besonders gut zur Untersuchung eines Diskurses einer nicht mehr existierenden Gesellschaft.
Thomas Masaryk, Viennois ou Pragois ?
Authors: Soubigou Alain
Published: January 2021

Tomás Garrigue Masaryk (1850-1937) fut le fondateur et le premier président de la République tchécoslovaque (1918-1935). Mais il est peu connu qu’avant 1914, il séjourna une quinzaine d’années de sa vie à Vienne, pour ses études, pour son premier poste universitaire puis comme député au Reichsrat. Président tchécoslovaque, il n’oublia pas cette longue fréquentation de Vienne, au point que dans son pays, il en paraissait suspect malgré sa popularité. Masaryk œuvra pour la réconciliation entre Prague et Vienne.
Manganese-Doped Silica-Based Nanoparticles Promote the Efficacy of Antigen-Specific Immunotherapy
Authors: Chandra Janin , Teoh Siok Min , Kuo Paula , Tolley Lynn , Bashaw Abate Assefa , Tuong Zewen Kelvin , Liu Yang , Chen Zibin , Wells James W. , Yu Chengzhong , Frazer Ian H. , Yu Meihua
Published: January 2021

Prophylactic human papillomavirus (HPV) vaccines are commercially available for prevention of infection with cancerogenic HPV genotypes but are not able to combat pre-existing HPV-associated disease. In this study, we designed a nanomaterial-based therapeutic HPV vaccine, comprising manganese (Mn4+)-doped silica nanoparticles (Mn4+-SNPs) and the viral neoantigen peptide GF001 derived from the HPV16 E7 oncoprotein. We show in mice that Mn4+-SNPs act as self-adjuvants by activating the inflammatory signaling pathway via generation of reactive oxygen species, resulting in immune cell recruitment to the immunization site and dendritic cell maturation. Mn4+-SNPs further serve as Ag carriers by facilitating endo/lysosomal escape via depletion of protons in acidic endocytic compartments and subsequent Ag delivery to the cytosol for cross-presentation. The Mn4+-SNPs+GF001 nanovaccine induced strong E7-specific CD8+ T cell responses, leading to remission of established murine HPV16 E7-expressing solid TC-1 tumors and E7-expressing transgenic skin grafts. This vaccine construct offers a simple and general strategy for therapeutic HPV and potentially other cancer vaccines.
Blockade of PD-1/PD-L1 Pathway Enhances the Antigen-Presenting Capacity of Fibrocytes
Authors: Afroj Tania , Mitsuhashi Atsushi , Ogino Hirokazu , Saijo Atsuro , Otsuka Kenji , Yoneda Hiroto , Tobiume Makoto , Nguyen Na Thi , Goto Hisatsugu , Koyama Kazuya , Sugimoto Masamichi , Kondoh Osamu , Nokihara Hiroshi , Nishioka Yasuhiko
Published: January 2021

Fibrocytes, a distinct population of collagen-producing, monocyte-derived cells, are involved in wound healing as well as fibrotic diseases. Recently, fibrocytes have been revealed to play a role in the tumor microenvironment, particularly under antiangiogenic therapy. In addition, combination cancer immunotherapy with immune checkpoint inhibitor and antiangiogenic agents have been developed for various cancers in the clinical setting, although the immunological background is not clear. In the current study, we aimed to determine the function of fibrocytes in tumor immunity induced by immune checkpoint inhibitor therapy. Human and murine fibrocytes were generated from PBMCs and lungs, respectively. The expression of costimulatory and inhibitory molecules on fibrocytes was examined by flow cytometry. The stimulation of CD8+ T cells by fibrocytes was examined in MLRs with a 3H-thymidine incorporation assay. Fibrocytes expressed CD80low and CD86high as a costimulatory molecule, and expressed PD-L1high, but not PD-L2, as a coinhibitory molecule. Without any stimulation, fibrocytes strongly enhanced the proliferation of CD8+ T cells in mice and humans. Treatment with anti-CD86 and -CD54 Abs inhibited the growth of CD8+ T cells induced by fibrocytes. Anti–PD-L1 Ab further enhanced the proliferation of CD8+ T cells, even in the OVA-specific MLR with OT-1Rag−/− mice. Importantly, fibrocytes derived from PBMCs of patients with lung adenocarcinoma or murine MC38 tumors augmented the proliferation of CD8+ T cells with PD-L1 blockade. These results suggest that fibrocytes infiltrating tumor sites may play a role in the antitumor immunity mediated by CD8+ T cells when the activity is further enhanced by PD-L1/PD-1 blockade.
Diagnosis and management of primary malignant tumors in the upper extremity
Authors: MacKay Brendan J. , McCormack Richard A. , Blank Alan T. , Bettiol Patrick , Cox Cameron , Brindley George , Rapp Timothy B.
Published: January 2021

Bone and soft tissue sarcomas of the upper extremity are relatively uncommon. In many cases, they are discovered incidentally during evaluation of traumatic injuries or common ailments such as rotator cuff tendonitis or tennis elbow. Thus, it is important for all orthopedic surgeons to understand the differential diagnosis, workup, and treatment for upper extremity lesions. An appreciation of the clinical and radiographic features of primary malignant lesions aids in identifying patients that need referral to an orthopedic oncologist and a multidisciplinary team.
Report of a Case of Paraquat Poisoning and Mediastinal Involvement
Authors: Samsamshariat Shiva , Vedaei Amirhossein , Jahangiri Sharare , Gavarti Mahdi Badiee , Sami Ramin , Taheri Abolfazl , Dorooshi Gholamali
Published: January 2021

Paraquat has been recognized as a highly toxic agent for pest removal and is used worldwide. In adults, paraquat poisoning for suicidal attempts is much more common than accidental exposure poisoning. Approximately 20% of patients with paraquat poisoning develop pneumomediastonium as a complication with a mortality rate of approximately 100%. A 19-year-old man patient was admitted to the poisoning emergency department of Khorshid hospital, who had ingested paraquat. He had nausea and vomiting and had normal vital signs and examination in admission. Initial treatment for the patient was done. The patient signs got worsened on the 21st day of hospitalization and had severe emphysema of the superficial and deep spaces of the neck, followed by bilateral pneumothorax, and severe pneumomediastinum. Unfortunately, the patient died on the 27th day of hospitalization. Purpose of the current study is to raise awareness of rare paraquat toxicity complications, treatment, and especially its lethal complications, including pneumomomediastonium.
Melorheostosis of Spine
Authors: Modi Jayprakash V. , Patel Harshil R.
Published: January 2021

Melorheostosis is a medical developmental disorder and mesenchymal dysplasia in which bone cortex widens and becomes hyperdense in a sclerotomal distribution. Most of the cases reported till now are confined to appendicular skeleton, rarely affecting spine. It is well known by its characteristic appearance of “melting wax flowing down a candle” on radiographs. Here we report a rare case of melorheostosis of thoracic spine in a middle-aged male patient with features of myelopathy treated by early decompression surgery, leading to complete relief of symptoms postoperatively. Final follow-up was of 2 years. It is a very rare, benign and disabling entity, and the diagnosis is primarily a radiological one. Early diagnosis and decompression surgery leads to dramatic improvement in clinical outcome and prevents unwarranted biopsy.
Correlation of Oral Mucositis with Timing of Radiation in Head and Neck Cancer - a Prospective Randomized Study on Chronoradiotherapy
Authors: Lavanya Lithika M , Arulponni TR
Published: January 2021

Context:

Study to reduce oral mucositis using chronoradiotherapy.

Aims:

This study aims to assess and compare oral mucositis and weight loss between two groups of patients on radiation-morning and evening group.

Settings and Design:

Prospective randomized study.

Subjects and Methods:

Sixty-four head and neck cancer patients were enrolled in the study. They were allotted into two arms, i.e., morning-arm A and evening-arm B using randomization. Baseline weight was recorded for all the patients. Weight and the grade of mucositis were recorded weekly during radiotherapy (RT) and at 2nd and 6th week post treatment in both the arms. Mucositis was graded based on the Radiation Therapy Oncology Group acute radiation morbidity scoring criteria.

Statistical Analysis Used:

The analysis of different grades and the incidence of mucositis at weekly intervals and follow-up were compared using Chi-square test. Weight loss was compared using t-test.

Results:

The progression of mucositis to higher grades was delayed by a week in the morning arm compared to the evening arm. Arm A (morning arm) developed Grade 3 mucositis in 21.9% patients versus 25% in the arm B (evening arm).

Conclusions:

Circadian rhythm has an impact on mucositis trending toward morning RT being less toxic with delayed progression and thereby decreased weight loss and better tolerance to radiation.
To Correlate the Immunohistochemical Analysis of p16 and Ki-67 in Oral Squamous Cell Carcinoma with the Background of Oral Submucous Fibrosis
Authors: Yadahalli Roopa , Kheur Supriya , Reddy Mamatha , Gupta Archana
Published: January 2021

Aim:

Oral submucous fibrosis (OSF) is a potentially malignant disorder with 7.6% of malignant transformation rate into oral squamous cell carcinoma (OSCC). The aim of the study is to assess the genetic markers p16 and ki-67 in OSF, OSCC, and OSCC with the background of OSF and control group.

Materials and Methods:

Ten cases of each group were stained with p16 and Ki-67 by immunohistochemistry technique.

Results:

Statistically significant results were found among the four groups with moderate-to-severe expression (P < 0.05) for Ki-67 and results were negative for p16 in all groups.

Conclusion:

According to our result, p16 is found not significant marker and Ki-67 can be useful as a proliferative index marker for malignancy development in oral precancerous conditions.
Bilateral Nevoid Hyperkeratosis of Nipple
Authors: Balpande Garima , Khatu Swapna , Chavan Dipali , Palaskar Nachiket
Published: January 2021

Nevoid hyperkeratosis of nipple and areola was first described by Tauber in 1923. It is a rare idiopathic disorder characterized by papular warty excrescences on the nipple and areola or both. Histopathology shows hyperkeratosis, acanthosis, papillomatosis, elongation of rete ridges, filiform interconnecting pattern, increased pigmentation in the basal layer, and sparse perivascular lymphocytic infiltrate. We report two cases of nevoid hyperkeratosis of nipple because of rarity of this condition.
Knowledge Attitude and Practices of Parents Towards Oral Health Maintenance Among Their Children and Correlation with Dental Caries Experience- A Cross-Sectional Study
Authors: Patil Anand Nanasaheb , Karkare Swati Ramesh , Jadhav Haridas Sopan , Sirikonda Saritha , Suryawanshi Vishal Bhaidas , Patil Saylee Narayan
Published: January 2021

Aim:

The aim of this study is to assess parent's knowledge, attitude, and practice (KAP) regarding their children's oral health maintenance and its correlation with dental caries experience.

Methodology:

A cross-sectional study was conducted among 504 parents of children aged 5–10 years between September 2013 and November 2014. A self-designed pretested 15-item questionnaire was used to assess the KAP. Dental caries experience was recorded as Decayed, Missing, Filled, Teeth (DMFT) and decayed-extracted-filled teeth among the children.

Results:

Dental caries prevalence among children was 61.1%. Good KAP was reported among 23% of the parents, 64% had fair, whereas 11.5% had poor KAP. One-way ANOVA showed a significant difference (P = 0.04) in deft scores among parents having good, fair, and poor KAP. The highest deft score was found among children of parents with poor KAP. The DMFT scores did not show a significant difference between the KAP categories (P = 0.76).

Conclusion:

Better knowledge, positive attitude, and good oral health practices followed for children by the parents will reflect the good dental health status of their children.
A Rare Case of Subcutaneous Dirofilariasis from a Tertiary Care Hospital in Western Maharashtra
Authors: Gandham Nageswari R. , Mirza Shahzad , Das Nikunja K. , Misra Rabindra N.
Published: January 2021

Dirofilaria are tissue nematodes which can cause zoonotic diseases and have been reported from all over the world. They are transmitted by zooanthropophilic arthropods. The genus causes subcutaneous ocular, pulmonary, and lesions in other subcutaneous tissues. The most commonly implicated species are Dirofilaria immitis and Dirofilaria repens. Confirmation of the diagnosis of dirofilariasis is mainly dependent upon microbiological identification of the parasite by macroscopical and microscopical analysis and histology. Documented reports from India are mainly from South India and of ocular presentations by D. immitis. Hence, this case of subcutaneous dirofilariasis is being presented. The present case was a 65-year-old female who presented with a swelling over the left lower side of the neck for 1 month. The patient underwent surgery for the mass and the lesion was excised. The mass was sent for microbiological identification. The parasite showed a cuticle, which had longitudinal as well as transverse striations. The parasite also had a body cavity, which had internal organs and structures. The worm was identified as Dirofilaria spp. based on morphological features, both microscopic and macroscopic. It is likely to be D. repens due to the presentation as a subcutaneous nodule with which it is more associated.
Abnormalities of Liver Function Tests in Acute Malaria with Hepatic Involvement
Authors: Bhattacharjee Debojyoti , Mukherjee Kheya , Sarkar Rehena , Chakraborti Goutam , Das Oindrila
Published: January 2021

Context:

Malaria is one of the major public health problems worldwide with increased morbidity and mortality. India has the fourth highest malaria burden in the world. Malaria parasite affects multiple organs of the body including liver, spleen, brain, kidney, blood vessels etc. Organ dysfunction predominantly seen in Plasmodium falciparum malaria, is not in Plasmodium vivax infections.

Aims:

The present study investigated the abnormalities of liver function test in acute cases of Plasmodium Falciparum infection.

Settings and Design:

A hospital-based case–control study conducted in a tertiary care center in West Bengal, India, for a duration of 7 months and included 53 acute falciparum malaria cases attending the outpatient department (OPD) and 47 age and sex matched patients, with complaints unrelated to the present study, as controls.

Materials and Methods:

Serum levels of bilirubin, serum glutamic oxaloacetic transaminase (SGOT), serum glutamic pyruvate transaminase (SGPT), alkaline phosphatase, total protein and albumin were assayed using autoanalyzer (Konelab 60i autoanalyser).

Statistical analysis used:

SPSS software version 20 (IBM, New York, USA).

Results:

In this study serum bilirubin (total, conjugated and unconjugated) SGOT, SGPT, alkaline phosphatase levels were highly significantly raised in cases with respect to controls. Levels of total protein, albumin and globulin in cases was not significantly different from the corresponding levels in controls.

Conclusions:

Hepatic function impairment in malaria is an important and potentially dangerous complication. Data from the present study can be useful for future research and also help in determining the prognosis and treatment.
A Study on the Advantages and Disadvantages of the Online Teaching Program Conducted in the Department of Anatomy, AIIMS, Raipur – Students' Perspective
Authors: John Meryl Rachel , Sharma Dhanesh Kumar , Poonuraparampil Joseph Abraham , Konuri Vijay Kumar
Published: January 2021

Background:

Medical education in India always relied on the traditional classroom method of teaching. The current COVID pandemic brought a situation where online classes have taken precedence over the traditional classroom teaching. Here we attempt to see from the students' perspective whether online classes can replace the traditional classroom teaching.

Aims and objectives:

We aimed to study the advantages and disadvantages of online learning.

Materials and methods:

Online live streamed classes using Free Conference Call app were held in the Department of Anatomy, AIIMS Raipur. Live streaming, pre-recorded lecture videos were supplemented by cadaveric dissection videos, assignments etc posted in Google Classroom. Feedback regarding the online classes were obtained from first year undergraduate medical students using Google Forms.

Results:

A total of 72 students responded to the survey. 57 students used mobile phones to access the classes. 10 students preferred the online classes with chalk and board lecture, 23 students preferred lecture with PowerPoint presentation while the rest preferred online classes with chalk and board lecture followed by PowerPoint presentation. Out of the total (n=72) respondents, majority of them experienced technical issues which hampered their online learning experience. Owing to this reason, 43 students showed preference for pre-recorded videos over online live classes. 41.7% of the students opined that online classes should be included as a part of MBBS anatomy curriculum.

Conclusion:

Online learning in the form of live classes and recorded videos can be included as a part of routine Anatomy curriculum but it can never be a substitute for interactive face to face classroom learning and practical session.
Microanatomy of Left Internal Thoracic Artery and Left Anterior Descending Artery
Authors: Kumari T. K. , Das Lola , Renuka K , Rajeev R , Raju Nithin K.
Published: January 2021

Introduction:

The knowledge of the microscopic structure of the left internal thoracic artery (LITA) and left anterior descending (LAD) artery can be correlated to the effectiveness of coronary artery bypass grafting using LITA graft. The objectives of the study were to study the microanatomy of the LITA and LAD artery, to compare the thickness of the wall of both arteries, and to report the elastic and muscular nature of these arteries.

Materials and Method:

Postmortem specimens of both the arteries from 50 samples of males were collected from the mortuary of Forensic Medicine, Government Medical College, Thiruvananthapuram. The tissues were subjected to hematoxylin and eosin and special staining. A photo micrometer was used for measuring the thickness of the wall, diameter of the lumen, and number of smooth muscles.

Results:

The mean thickness of tunica intima (TI) of LITA and LAD was 18.8 μ and 129.8 μ, respectively. The lumen diameter of LITA and LAD was 945.25 μm2 and 1653.45 μm2, respectively. The thickness of tunica media (TM) and the diameter of the lumen of LITA were increased with age. The number of smooth muscles in LITA was decreased with age. The thickness of TI, media, adventitia, and the luminal diameter of LAD were increased with age. The number of smooth muscles in LAD was decreased with age.

Conclusion:

Proximal segments of LITA had more elastic fibers arranged in concentric lamellae, especially in the outer zone. The TM of LAD has a greater number of smooth muscles and a smaller number of elastic fibers.