bluuebunny/crossref_metadata_2025 huggingface dataset:
Los trabajos de Persiles y Sigismunda, historia setentrional de Miguel de Cervantes: Estado de la cuestión y su actualidad para hispanistas nórdicos
Authors: Davenport Randi Lise
Published: November 2019

Miguel de Cervantes’ posthumous novel, Los trabajos de Persiles y Sigismunda, historia setentrional, published in 1617, has in the past decades received renewed attention from Cervantes scholars. This article gives an overview of the main perspectives of current research at the 400th anniversary of the novel that the author himself considered his literary testament. It concludes offering some brief reflections on its particular relevance for Nordic hispanists.
Cannabis sativa-mediated synthesis of gold nanoparticles and their biomedical properties
Authors: Hameed Safia , Ali Shah Sajjad , Iqbal Javed , Numan Muhammad , Muhammad Wali , Junaid Muhammad , Shah Sumaira , Khurshid Razia , Umer Fazal
Published: November 2019

Nanotechnology describes precision manufacturing of materials at the nano scale. Nanotechnology has a vast range of applications, such as medicines, electronics, biomaterials and energy production. The present research work is a green eco-friendly approach to the production of gold nanoparticles (Au-NPs) by using the plant extract of Cannabis sativa. The appearance of a ruby-red color from a greenish color is the primary indication of the formation of Au-NPs. C. sativa contains some active compounds that were found to be responsible for the reduction of gold and converting it into a bioactive metal. The synthesized Au-NPs were characterized by ultraviolet–visible spectroscopy, high-resolution scanning electron microscopy and Fourier transform infrared spectroscopy. In vitro antimicrobial, cytotoxicity, biocompatibility and enzyme inhibition assays were performed. Notable antimicrobial activities are reported. Bioinspired Au-NPs were found effective against bacterial and fungal strains. A 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay was performed to check the leishmanicidal activity against amastigotes (IC50: 171·00 ± 2·28 μg/ml) of Leishmania tropica. Brine shrimp lethality was also shown by the bioinspired Au-NPs. Furthermore, substantial protein kinase inhibition was noted.
ESTIMATION OF THE RADIOACTIVE SOURCE TERM FROM RDE ACCIDENT POSTULATION
Authors: Udiyani Pande Made , Husnayani Ihda , Setiawan Mohamad Budi , Kuntjoro Sri , Adrial Hery , Hamzah Amir
Published: November 2019

The design process of Experimental Power Reactor (Reaktor Daya Eksperimental/RDE) has been carried out by BATAN for the last five years, adopting HTGR-type reactor with thermal power of 10 MW. RDE is designed with the reference of similar reactor, namely HTR-10. During this process, source term estimation is required to prove the safety of RDE design, as well as to fulfill the concept of As Low As Reasonably Achievable (ALARA) in radiation protection. The source term is affected by the magnitude of the radioactive substances released from the reactor core due to an accident. Conservative accident postulations on the RDE are water ingress and depressurization accidents. Based on these postulations, source term estimation was performed. It follows the mechanistic source term flow, with conservative assumptions for the radioactive release of fuel into the coolant, reactor building, and finally discharged into the environment. Assumptions for the calculation are taken from conservative removable parameters.The result of source term calculation due to the water ingress accident for Xe-133 noble gas is 8.97E+12 Bq, Cs-137 is 3.59E+07 Bq, and I-131 is 4.34E+10 Bq. As for depressurization accident, the source term activity for Xe-133 is 3.90E+13Bq, Cs-137 is 1.56E+07 Bq, and I-131 is 1.89E+10Bq. The source term calculation results obtained in this work shows a higher number compared to the HTR-10 source term used as a reference. The difference is possibly due to the differences in reactor inventory calculations and the more conservative assumptions for source term calculation.Keywords: RDE, HTGR, Radioactive, Source term, accident
ROUTING DESIGN ON THE PRIMARY COOLING PIPING SYSTEM IN PLATE-TYPE CONVERTED TRIGA 2000 REACTOR BANDUNG
Authors: Wardhani Veronica Indriati Sri , Rahardjo Henky Poedjo , Tursinah Rasito
Published: November 2019

In 2015, research activities to modify TRIGA 2000 Reactor Bandung fuel element from cylindrical to plate-type have been initiated. By using plate-type fuel elements, core cooling process will be altered due to different generated heat distribution. The direction of cooling flow is changed from bottom-to-top natural convection to top-to-bottom forced convection. This change of flow direction requires adjustment on the cooling piping system, in order to produce simple, economical, and safe piping route. This paper will discuss the design of suitable piping routing based on pipe stress and N-16 radioactivity. The design process was carried out in several stages which include thermal-hydraulic data of reactor core to determine the process variables, followed by modeling various pipeline routes. Based on available space and ease of manufacture, four possible alternative routings were determined. Four routings were produced and analyzed to minimize the amount of N-16 radioactivity on the surface of the reactor tank, prolonging the cooling fluid travel time to reach at least five times of N-16 half-life. Subsequent pipe stress analysis using CAESAR II software was conducted to ensure that the piping system will be able to withstand various loads such as working fluid load, pipe weight, along with working temperature and pressure. The results showed that the occurred stresses were still below the safety limit as required in ASME B31.1 Code, indicated that the designed and selected pipeline routing of primary cooling system in the Plate-type Converted TRIGA 2000 Reactor Bandung has met the safety standards.Keywords: TRIGA reactor, Cooling system modification, Pipeline routing design, Pipe stress analysis, N-16 radioactivity
POST DEMOKRASİ VE SİYASİ PARTİ KAVRAMLAŞTIRMASINI PIERRE BOURDIEU ÜZERİNDEN OKUMAK
Authors: KOÇ Yunus
Published: November 2019

Modern dönemde demokrasi, halkın yönetiminin
garantörü olarak görülür. Halk, egemenliğini; demokrasinin en önemli aygıtı
olan siyasi partiler vasıtasıyla gerçekleştirir. Halkı temsil etme görevi
verilen siyasi partiler, postmodern dönemde yeniden tanımlanmıştır. Siyasi
partilere yüklenen yeni anlamlarla yönetimde hâkim olanın kim ya da kimler
olduğu mevzusu tartışılmaya başlanmıştır. Haliyle bu durum, demokrasinin yeni
bir modeli olan “post demokrasinin”, ne olduğunun sorgulanmasını zorunlu hale
getirmiştir. Demokratik ilkelerin yeniden belirlendiği, hakikat olanın yeniden
şekillendirildiği post dönemde; demokrasinin nasıl evirildiğinin sorgulanması,
en önemli enstrümanlarından olan “siyasi partiler” üzerinden okunması
çalışmamızın amacını oluşturmuştur. Bu perspektifle post demokrasi kavramı,
Bourdieu’nun sermaye kuramına dikkat çekilerek ele alınmıştır.
Effect of pre-game photobiomodulation on muscle recovery in professional soccer players: study protocol for a randomized, cross-over, sham-controlled, triple-blind, clinical trial
Authors: Glória Igor Phillip dos Santos , Junior Ernesto Cesar Pinto Leal , Politti Fabiano , Herpich Carolina Marciela , Smith Denis , Carvalho Leandro Silva de , Gomes Cid André Fidelis de Paula , Gonzalez Tabajara de Oliveira , Biasotto-Gonzalez Daniela Aparecida
Published: November 2019

Background: Photobiomodulation with low-level laser therapy (LLLT) has been widely used in clinical practice for diverse purposes, such as modulation of the inflammatory process, acceleration of the tissue repair process, pain relief and the enhancement of post-exercise recovery. Studies have demonstrated a beneficial interaction between photobiomodulation and the production of creatine kinase, with a reduction in the release of this marker of muscle damage when laser and/or LEDs is administered prior to high-intensity physical activity. Objective: The aim of the proposed study is to determine the influence of pre-exercise phototherapy on post-exercise muscle recovery. Methods: A randomized, cross-over, sham-controlled, double-blind, clinical trial is proposed. The participants will be healthy professional soccer players aged 15 to 20 years from the same team with a body mass index within the ideal range (20 to 25 kg/m2 ) and no history of lower limb musculoskeletal injuries or surgery or back surgery in the previous six months. The athletes will be allocated to two groups based on the previously calculated sample size and will be blinded to allocation. Creatine kinase will be measured and the subjective perception of fatigue will be determined for each participant. The volunteers will then be randomly allocated to Group A, which will receive active phototherapy, and Group B, which will receive sham phototherapy. The athletes will undergo reevaluations immediately after as well as 48 hours after a football match. The data will be submitted to statistical analysis and the level of significance will be set to 5%. This study is registered with Clinical Trials under protocol number: NCT03416998.
The acute influence of stretching in muscle resistance strength: transversal intervention study.
Authors: Petto Jefferson , Cruz Tarcísio de Almeida , Patrício Diego Silva , Sacramento Marvyn de Santana do , Almeida André Ricardo da Luz , Almeida Luís Alberto Bastos de , Santos Alan Carlos Nery dos , Diogo Diego Passos
Published: November 2019

Antecedentes: O alongamento muscular é frequentemente aplicado como preparação para o treinamento de resistência, no entanto, uma literatura diverge quanto à sua resposta à força de resistência muscular. Objetivo: mostrar se a intensidade e o tempo de alongamento modificam a força da resistência. Métodos: O estudo inclui 30 homens jovens saudáveis, com 22 ± 2,5 anos de idade, praticando exercícios neuromusculares há menos de seis meses. Os participantes fizeram um teste de previsão de carga máxima (MLPT) no supino e após uma semana retornaram ao sorteio e execução do: Stretch Protocol (SP) - 60 segundos na amplitude máxima sem assistência; Protocolo de Flexão (FP) - 60 segundos de acompanhamento com assistência externa;e Protocolo de Base (PA) - exercício imediato. Todos os participantes passaram por todos os protocolos sempre realizados em segundas-feiras, realizando como repetições máximas com 70% da carga utilizada no MLPT. Para comparar os resultados dos diferentes dias de coleta, foi usado um ANOVA com TUKEY post-hoc. Todas as análises adotaram um valor de p≤0,05 como significativo. Resultados: a PA apresenta resultados maiores do que no SP e FP. Não houve diferença estatística entre SP e FP. Conclusão: 60 segundos de alongamento muscular passivo causam uma diminuição da força de resistência muscular, a redução de intensidade.
PRIVATE INTERNATIONAL LAW IN THE 21ST CENTURY: CONTEMPORARY CHALLENGES AND DEVELOPMENT PROSPECTS
Authors: Zasemkova O. F.
Published: November 2019

In the context of integration, globalization and increasing complexity of private law relations complicated by a foreign element, private international law acquires special importance. Being influenced by the processes named above, it is not only rapidly developing and acquiring new directions for development. Private international law is also facing new global challenges. In this regard, the article attempts to analyze the main trends in the development of private international law in the 21st century revealing new trends and threats that it may face in modern conditions.Based on the results of the analysis, the author comes to the conclusion that the main trends in the development of private international law include the expansion of the scope of its application, as well as the unification and harmonization carried out within the framework of various international organizations at both universal and regional levels. The Hague Conference on Private International Law and the United Nations Commission on International Trade Law (UNCITRAL) play the most important role in this process. Finally, one more important trend in the development of private international law is constituted by the attempt to adapt to new, rapidly changing realities leading to a substantial modernization of the methods of cross-border private law disputes resolution.
TRANSFORMATION OF THE BASIC PRINCIPLES OF INDUSTRIAL PROPERTY PROTECTION IN CROSS-BORDER RELATIONS IN THE PRESENT-DAY CONDITIONS
Authors: Shahnazarov B. A.
Published: November 2019

The author has investigated the basic principles of industrial property protection in their dynamic development in cross-border relations. The author elucidates the territorial principle of industrial property protection in the context of the necessity to overcome it. It is noted that in most industrial property cases the principle of territoriality (territorial independence of protection in respect of objects of industrial property) is more often used as compared with copyright cases.In fact, States create certain conditions for overcoming the (partial) territorial principle of protection when, at the international level, international protection mechanisms are being developed to protect industrial property. The creation of such mechanisms obliges the States to recognize declaratory documents (international applications) and single sign-ons (international registrations), to provide protection to the facility that has been granted protection abroad (e.g. in the case of appellation of origin or geographical indication registered in the country of origin). Indeed, such an overcoming is conditional, but it always reflects the interests of applicants and rights holders and seems to be extremely important in the modern context of globalization, expanding markets and cross-border technology exchange.At the same time, at the current stage of development of the system of the legal regulation of industrial property in cross-border relations, the principle of national treatment on the basis of unified action of international mechanisms applied for the industrial property protection has been partly transformed into the principle of the international treatment extending the common rules for establishing rights to industrial property on actors from a large number of countries.It would be possible to speak about overcoming the territorial principle of protection if the fundamental principle of protection of industrial property — the principle of national treatment — were transformed into the principle of international treatment.The author highlights an important character of the principle of conventional priority and the need for its extension to other objects of industrial property except for those in respect of which priority is not inherently possible (appellations of origin, geographical indications, indications of origin). The problem of implementation of the principle of exhibition priority has been explored separately.
EVOLUTION OF THE LEGAL CONCEPT OF "FOREIGN INVESTMENT" IN A NETWORK SOCIETY
Authors: Viktorova N. N.
Published: November 2019

The paper deals with the problems of definition of the concept "investment" in multilateral and bilateral investment treaties. The author shows how the approach to the definition of "investment" in international investment agreements has changed over time, how this concept differs in modern agreements from those enshrined in agreements concluded more than ten years ago. It is noted that today we can talk about the trend of a broad definition of the concept of investment in international treaties, that is, investments are understood as any kind of property values; further the author specifies what applies to them.International treaties on the protection and promotion of investment also include the right to engage in business activities. It turns out that investment disputes can arise from ordinary commercial activities, for example from a contract of sale. However, there are documents that do not include monetary claims arising from commercial contracts, such as the 2012 model bilateral investment Treaty of the South African development Community.Generally, investment protection agreements do not distinguish between direct and portfolio investments. Therefore, portfolio investments also enjoy the protection of these investment treaties. However, some of the international investment agreements that are currently being concluded specify that portfolio investments are excluded from their scope, such as the Model bilateral investment Treaty of the South African Development Community.In the literature there are three approaches to the qualification of foreign arbitral awards as a foreign investment. According to one of them, the award is an investment, because it is part of the entire activity of the investor. Some modern international investment agreements contain provisions according to which arbitration, judicial decisions are not investments.
INSTITUT LAUE-LANGEVIN (ILL) AS A FORM OF SCIENTIFIC COOPERATION
Authors: Zaplatina T. S.
Published: November 2019

The integration of states in the field of education has given rise to the expansion of various forms of cooperation in this area. The subject of the study is one of the large-scale scientific projects called "megasience" — Institut Laue-Langevin (ILL), based in Grenoble, France. Such international research centers are designed to achieve breakthrough discoveries, like the Large Hadron Collider (LHC) in Europe, the Laser Interferometric Gravitational-wave Observatory (LIGO) in the United States, and neutron research through the research reactor complex PIK, under construction in Russia. Large research infrastructures are an important phenomenon of public life. In France, megasience installations are officially called "very large research infrastructures", briefly TGIR, in Australia — "landmark research infrastructures".The Institut Laue-Langevin is established as a national legal entity and is managed by three partner countries: France through the French Alternative Energies and Atomic Energy Commission (CEA) and the French National Centre for Scientific Research (CNRS); Germany through the Jülich Research Centre (FZJ) and the United Kingdom through the Science and Technology Facilities Council (STFC).This form of cooperation between countries, integration of states in the field of education has a number of positive aspects and can be used in Russia to find the most effective model for organizing mega-science projects. Thus, ILL make ot possible to use different sources of funding-funds from both the state and private research and grants, as well as European projects. The ILL provides for the possibility of diverse cooperation and participation of various states, the involvement of scientists and individuals, including non-European countries, open membership. The positive features are also the ease of management and reorientation of ILL, flexibility, as well as the ease of cooperation with various institutions of both national and European and international level.
THE BASIS OF LEGAL REGULATION OF PUBLIC PROCUREMENT IN THE WEST AFRICAN ECONOMIC AND MONETARY UNION (UEMOA)
Authors: Kamalyan A. M.
Published: November 2019

The paper analyzes the key supranational public procurement instruments adopted within the framework of the West African economic and monetary Union, especially the legally binding directives (Directive 04/2005 on the award, performance and payment of public contracts and Directive 05/2005 on the control and regulation of public procurement), which require further implementation into the national legislation of the member states. Special attention is given to the documents that, although they are advisory in nature or only indirectly affect the issue under study, but have had a significant impact on the formation of directives — the Regional program for improving the efficiency of public procurement and the UEMOA Code on transparency in public finance management. The principles of legal regulation of public procurement in the UEMOA are revealed: the principle of cost — effectiveness and efficiency of procurement; the principle of free access to the public procurement market; the principle of equal treatment of candidates and mutual recognition; the principle of transparency, rationality, modernity of procurement procedures and the possibility of tracking them; the principle of non-discrimination on the basis of nationality in relation to enterprises of the UEMOA member states and the principle of non-violation of competition when transferring a state contract to subcontracting; de minimis principle. A brief description of the procedures for awarding public contracts established in this organization, namely tender (there are several varieties of tender, the main of which are open and closed) and procurement from a single supplier. Some aspects of the legal regulation of public procurement in UEMOA are compared with other integration associations, in particular with the European Union and the Common market of South America (MERCOSUR).
COMPLEX CONFLICTS OF LAW AND HOW TO DEAL WITH THEM: REVIEW OF THE MONOGRAPH BY A.S. GAMBARYAN AND L.G. DALLAKYAN "CONFLICT OF LAW RULES AND THEIR COMPETITION" (MOSCOW: YURLITINFORM PUBL., 2019. 160 P.)
Authors: Petrov A. A.
Published: November 2019

The reviewed monograph is devoted to the theoretical and legal puzzle — complex conflicts of law (coincidence of conflicts, competition of conflict of laws). The book contains a number of valuable ideas on the topic of research. In particular, the authors correctly distinguish between positivized conflict-of-laws rules and principles (maxims) developed by lawyers to overcome conflicts (conflict-of-laws rules of interpretation), which may be inconsistent with each other. This gives rise to complex conflicts. The authors successfully demonstrate this by the example of the complex fate of the lex posteriori derogat priori principle in the legal system of Armenia. The work provides a comparative legal study of the legal regulation of the resolution of conflicts of norms, including complex conflicts, in the post-Soviet States. The hierarchical system of conflict criteria proposed by the authors to overcome complex conflicts of law is very interesting. In addition, the monograph describes in detail the problems of "non-systemic conflicts" in law, which are understood as antinomies of principles and norms of law and inconsistency between the principles of law. At the same time, there are a number of controversial theses in the work, for example, on the priority of the humanistic substantive criterion of conflict resolution over traditional legal criteria (such as lex superior, lex specialis, lex posterior); on the need to allocate competence and industry criteria as separate criteria for overcoming conflicts; on the restrictive author’s interpretation of the scope of application of the lex specialis conflict principle. These controversial ideas are criticized in the review in a well-reasoned manner.
Entrevista a Marika Vila
Authors: Vila Marika , Bettaglio Marina
Published: November 2019

En esta entrevista, la filóloga y artista gráfica Marika Vila analiza la presenciafemenina en el discurso del cómic español, contrastándola con surepresentación en el discurso misógino y homófobo que ha dominado el mediodesde sus orígenes. Su trabajo de investigación resalta las transformacionesde la narrativa gráfica española desde los años de la Transición – cuando, conel advenimiento de la democracia, se asiste al nacimiento del cómic de autor yal Boom del cómic para adultos – hasta la época actual en la que se apreciaun gran surgimiento de obras de autoría femenina. Asimismo, gracias a untrabajo de investigación de largo recorrido, Vila recupera la visibilidad yresistencia de las autoras pioneras. A partir de las preguntas de MarinaBettaglio, Trujillo revisa el pasado del cómic español desde una perspectiva degénero para destacar la necesidad de rescatar el trabajo de las creadoras yentender su aporte a lo largo de su historia.
Entrevista a Marcela Trujillo
Authors: Trujillo Marcela , Bettaglio Marina
Published: November 2019

En esta entrevista, la artista gráfica chilena Marcela Trujillo describe sutrayectoria personal como dibujante, destacando su pasión por la pinturafigurativa, así como la influencia del cómic underground norteamericanoautobiográfico de autoría femenina en su formación artística. Al trazar unbreve panorama de la narrativa gráfica latinoamericana actual, resalta lapresencia de un número creciente de autoras empeñadas en una renovaciónde este ámbito de creación artística. En diálogo con Marina Bettaglio, MarcelaTrujillo describe los aspectos más innovadores del trabajo de un grupoheterogéneo de autoras cuyas temáticas abarcan la relación con el cuerpo, lasexualidad y la maternidad, y nos revela su labor como co-fundadora y coeditorade la revista Brígida en la promoción de las obras de autoras chilenasy latinoamericanas.
Evaluación experimental de la eficiencia de un colector solar de tubos evacuados sin y con tubo de calor
Authors: Eufracio Arias Wilder Efraín , Abregú Rodríguez Nathaly Ibeth , Rodríguez Espinoza. Dayana
Published: November 2019

En la presente investigación se evaluó experimentalmente la eficiencia de un colector solar de tubos evacuados (CSTE) sin y con tubo de calor en días soleados, parcialmente nublados y nublados. En total se realizaron 46 experimentaciones durante 23 días: marzo a junio del 2017, con dos CSTE sin y con tubo de calor de 100 y 120 L, respectivamente. La radiación solar en la superficie horizontal y temperatura del agua en la salida del tanque de almacenamiento se registraron durante 5 horas (9:30 am a 2:30 pm) en intervalos de 30 y 10 s, respectivamente. Para las representaciones y estimaciones de la eficiencia se utilizó el lenguaje de programación Matlab.Los resultados muestran una ligera superioridad de eficiencia del CSTE con tubo de calor (60,35%, 61,21% y 66,08%) comparado al sin tubo de calor (57,17%, 57,29% y 59,56%), medidos en días soleados, parcialmente nublados y nublados, respectivamente. Y se observa que en el CSTE con tubo de calor es mayor el incremento de la eficiencia en días nublados por las menores pérdidas de calor debido a un menor incremento de la temperatura, generando un mayor aprovechamiento de la energía solar incidente. El análisis de varianza indicó que la condición de la radiación solar y tubo de calor del CSTE no influyen significativamente en la eficiencia energética de este colector solar.De acuerdo a la condición de radiación solar (días soleados, parcialmente nublados y nublados), el CSTE con tubo de calor presentó una mayor eficiencia de 3,20 %, 3,92 % y 6,52%, respecto al CSTE sin tubo de calor.
Caracterización petrofísica de la formación oficina en un sector del bloque carabobo mediante métodos fractales
Authors: Mederos V. Ignacio J.
Published: November 2019

El propósito es generar modelos de isopropiedades petrofísicas a partir de métodos estadísticos que contribuyan en la caracterización estática de yacimientos, el concepto de fractal el cual se define como un objeto cuya estructura se repite a diferentes escalas, fue el método aplicado. Considerando que el campo Carabobo presenta bajo ángulo, se decidió la utilización de fractales en esta investigación introduciendo como registros de entrada los de rayos gamma, densidad, resistividad y el de porosidad efectiva, a los cuales se le aplicó método para la elaboración y el análisis de modelos de isopropiedades petrofísicas, ya que cumplen con la condición de que los registros se comportan como series en tiempo, con aleatoriedad y pueden ser normalizados. A partir del análisis por la técnica de rango escalado “R/S” (re-escalamiento) se obtiene el exponente o coeficiente Hurst (H) que indica el grado de rigurosidad y persistencia de los datos con la distancia, estableciendo de esta manera el alcance de los mismos al realizar la interpolación fractal de los pozos, generando así pseudopozos. De la integración de los pozos originales y los pseudopozos generados se estimó la distribución espacial de las propiedades petrofísicas. Corroborando que es una herramienta útil, reduce la incertidumbre en la determinación y extensión de prospectos en procesos exploratorios y mejora la visualización de las propiedades petrofísicas tanto horizontal como verticalmente
Análisis litológico para incremento de la tasa de perforación en la cuenca oriente Ecuador
Authors: Ayala Diego , Bastidas Alejandro , Loaiza Marco , Ayala Silvia
Published: November 2019

Se evaluará la tasa de perforación y la trayectoria de los pozos en estudio a partir de la información litológica, los esfuerzos regionales y la estabilidad en la cara del pozo para adaptar las trayectorias a la litología regional de forma tal que se aproveche de las características de la misma para mejorar la perforabilidad e incrementar la tasa de penetración.Este artículo expone lo desafiante que resulta alinear todas las variables geológicas y disponerlas de manera que permitan optimizar la perforación por cuanto existe un interés puntual dentro del reservorio desarrollado y planteado por los ingenieros de yacimientos, el mismo que en ocasiones impide aprovechar la orientación de los esfuerzos principales en la cara del pozo, así como los esfuerzos regionales de la zona perforada. Al establecer una relación entre la litología, las características geomecánicas, los problemas al perforar y la tasa de penetración de los pozos analizados se determinó aquellos parámetros que permitieron en cada sección del pozo incrementar la tasa de perforación como respuesta a una mejor adaptación de la geología regional.El trabajo incluye sugerencias de las posibles direcciones que podría tomar un pozo basados en los diagramas polares de estabilidad lo que conjuntamente con una trayectoria perpendicular a los esfuerzos regionales propiciaría un incremento en la tasa de penetración.
FORMATION AND USE OF THE DEVELOPMENT CAPACITY OF REGIONAL ECONOMIES CENTRAL FEDERAL
Authors: A. E. Demyanenko
Published: November 2019

Purpose: The research is devoted to the potential of economic development of regions of Central Federal District, in a section of determination of regularities, trends, and features of their social and economic state and development.

Methodology: The conducted research is based on materials of official state statistics, with the use of a method of komparativny analysis. The carried-out analysis allows revealing a row specific, observed on regions of Central Federal District, regularities, trends and features of a social and economic state and development.

Result: Essential distinctions on the analyzed territorial subjects of the federation, investments and bank deposits making considerable specific weight in the consumer investment portfolio of potential of development of regional economy are revealed. Integrated assessment of the indicators demonstrating the many-sided nature of specialization of regional production is carried out taking into account their correlation importance information of a gross regional product.

Applications: This research can be used for universities, teachers, and students.

Novelty/Originality: In this research, the model of the Formation and use of the Development Capacity of Regional Economies Central Federal is presented in a comprehensive and complete manner.
FINDING EXACT NUMBER OF PEAKS IN BROADBAND UV-VIS SPECTRA USING CURVE FITTING METHOD BASED ON EVOLUTIONARY COMPUTING
Authors: AVCU Fatih Mehmet , KARAKAPLAN Mustafa
Published: November 2019

High performance calculations are
needed in order to resolve analytic signals of the day. But it requires very
long periods of time to perform these calculations with single processor
systems. In order to reduce these calculation times, there is a need to turn to
parallel programming algorithms that share more than one processor. Recently,
solving complex problems with genetic algorithms has been widely used in
computational sciences. In this work, we show a new method of curve fitting via
genetic algorithm based on Gaussian functions, for deconvolution the
overlapping peaks and find the exact number of peaks in UV-VIS absorption
spectroscopy. UV-VIS spectra are different than other instrumental analysis
data. The resolution of UV-VIS spectra is a complicated because of that the
absorption bands are strongly overlapped. Useful information about molecular
structure and environment can often be obtained by resolving these peaks
properly. The algorithm was parallelized with the island model in which each
processor computes a different population. This method has been used for resolving
of the UV-VIS overlapping spectrum. The method particular algorithm is robust
by bad resolution or noise. The results show that it is satisfactory and
clearly show the effectiveness of the proposed method.
Gestational and congenital syphilis situation in Colombia, a challenge to the General system of Social Security in Health
Authors: Cruz-Concha Adriana Raquel
Published: November 2019

Syphilis is a sexually transmitted infection (STI) caused by Treponema Pallidum, and is considered a serious public health problem as it affects more than 12 million people worldwide. It is estimated that over two million pregnant women are infected with syphilis each year worldwide, and a significant number of cases (692,100 to 1,53 million), are untreated (1). When it occurs in pregnant women it is easily transmitted to the fetus, causing complications in up to 81% of cases, including stillbirth, early neonatal death , prematurity, low birth weight or congenital infection (2).In Colombia, gestational and congenital syphilis is notifiable, and the figures reported by the System of Public Health Surveillance (sivigila, for its acronym in Spanish), are among the highest in Latin America and the Caribbean. In 2011 Colombia reported 2.9 cases of congenital syphilis / 1000 live births (3), a value which is worth almost six times higher than the target set by the Pan American Health Organization (PAHO) in its Elimination of Congenital Syphilis Plan (2, 4). The Colombian Pacific coast provides the country with a significant number of cases each year, being the port of Buenaventura, in Valle del Cauca, one of the worst affected areas, reporting on 2010, 141 cases of congenital syphilis, nine of which ended in a fatal outcome (5).
Mecanismos de modulación de la respuesta inmune por Chlamydia trachomatis asociados a infertilidad
Authors: López-Castro Tatiana Marcela , Rojas-Díaz Ever Leonardo , Rojas-rojas Fabio Noriel , Díaz-Yamal Ivonne J. , Muñoz-Cerón Jairo
Published: November 2019

Introducción: la infertilidad, problema clínico y social que afecta del 13 al 15% de las parejas en el mundo, es causada, entre otros, por la enfermedad pélvica inflamatoria ocasionada por varios agentes infecciosos entre los cuales se destaca la Chlamydia trachomatis. Este agente infeccioso posee mecanismos moleculares con los cuales modula la respuesta inmune del huésped y produce cambios en la célula infectada para permitir su supervivencia, ocasionando que la respuesta del sistema inmunológico se establezca en forma crónica, con la consecuente inflamación permanente y con ello secuelas como cicatrices y obstrucción de la trompa de Falopio. El objetivo de esta revisión es ofrecer una actualización de conocimiento en inmunobiología de la infección por Chlamydia trachomatis y su relación con la infertilidad.Materiales y métodos: se realizó una revisión de la literatura en diferentes bases de datos: PubMed/ Medline, Science Direct, Ovid, desde enero del año 1995 a enero del 2012, incluyendo artículos de revisión y estudios clínicos.Resultados: en la actualidad se sostiene que la inmunomodulación que caracteriza la infección por Chlamydia trachomatis, los mediadores inflamatorios implicados en la respuesta inmune, y la posible aunque poco estudiada susceptibilidad genética del huésped, se relacionan estrechamente con la génesis de la infertilidad por factor tubárico.Conclusión: la infertilidad causada por Chlamydia trachomatis tiene su origen en la respuesta inmunológica del huésped y en la modulación por parte de este agente infeccioso, lo que lleva a inflamación crónica, cicatrización y obstrucción de la trompa de Falopio.
Descripción de la presencia de anticuerpos antianexina V, cardiolipina y B2-glicoproteína I en mujeres con pérdidas gestacionales recurrentes en la ciudad de Medellín, Colombia
Authors: Mejía-Mejia María Victoria , Segura-Cardona Angélica María , Velásquez-Escobar María Camila , Arango-White María Camila , Abad-Restrepo Jazmín , Orrego-Vélez Martín , Álvarez-Arango Santiago , Uribe-Pardo Carlos Ignacio
Published: November 2019

Objetivo: describir la frecuencia de anticuerpos antianexina V en una serie de mujeres que presentaron aborto recurrente en la ciudad de Medellín.Materiales y métodos: se llevó a cabo una serie de casos constituida por mujeres sanas que acudían a consulta ginecológica por historia de pérdidas gestacionales recurrentes caracterizadas por dos o más abortos en el primer trimestre de gestación, en dos instituciones prestadoras de servicios de salud de segundo y tercer nivel de complejidad, y a la consulta privada de algunos ginecólogos de la ciudad de Medellín que aceptaron participar en el estudio. Se excluyeron las mujeres con diagnóstico de síndrome antifosfolípido secundario. Se evaluaron las características sociodemográficas, los antecedentes obstétricos y médicos con énfasis en hipertensión arterial y trombosis. También se evaluaron los anticuerpos anticardiolipina, anticoagulante lúpico, número de anticuerpos antiß2-GPI y número de anticuerpos antianexina V. La información se tabuló en una hoja de cálculo de Microsoft Excel y se procesó en el programa estadístico Stata 10.0, en el análisis estadístico se utilizó estadística descriptiva.Resultados: se encuestaron 65 mujeres con edades entre los 18 y 46 años, la mitad de las pacientes reportaron 2 abortos antes de la décima semana, y la otra mitad después de esta. En los resultados de los anticuerpos anticardiolipina se encontró que el 4,6% (3) de las pacientes presentaron anticuerpos positivos IgM y el 3,1% (2) tenían anticuerpos positivos IgG. El 3,1% (2) de las mujeres presentaron anticuerpos antiß2-GPI IgG e IgM. El 4,6% (3) de las pacientes presentaron anticuerpos positivos antianexina IgG y un 12,3% (8) de estas presentaron un resultado indeterminado.Conclusiones: se evidencia la presencia de anticuerpos antianexina en las pacientes estudiadas, aunque un subgrupo de mujeres presentó un resultado indeterminado; surge la hipótesis de que la anexina V podría ser un factor importante e independiente de los anticuerpos cardiolipina y β2-GPI en las pérdidas gestacionales recurrentes.
Comentarios sobre el artículo "Misoprostol intravaginal administrado ambulatoriamente para inducción selectiva del trabajo de parto en pacientes con embarazo a término. Estudio de cohorte"
Authors: Montoya-Fernández Jeanette , León-Jiménez Franco
Published: November 2019

Estimado Señor EditorEncontré interesante el artículo publicado por MorenoEscallón en el volumen 63, número 1 de enero-marzo 2012 de la Revista Colombiana de Obstetricia y Ginecología sobre el uso de misoprostol intravaginal para la inducción del trabajo de parto (1), y consideré importante hacer una revisión respecto al uso de este medicamento.En los últimos años se ha observado un incremento de la inducción del parto por complicaciones médicas u obstétricas del embarazo, para lo cual se han utilizado diversos medicamentos (2).El misoprostol es un análogo sintético de la prostaglandina E1 que en un inicio fue empleado como tratamiento de úlcera péptica y para prevenir complicaciones gastrointestinales en pacientes que ingerían AINEs (3, 4), y en los últimos años ha sido muy estudiado como medicamento para la inducción del parto por su efecto en la madurez cervical y la contractilidad uterina (4).Este fármaco tiene la ventaja de ser económico, se puede mantener a temperatura ambiente y existen diversas vías de administración: vaginal, oral, sublingual o rectal (3).Se han realizado diversos estudios para la búsqueda de una dosis y vía de administración adecuadas. Jindal et al. realizaron un ensayo clínico randomizado doble ciego comparando el uso de 50 µg de misoprostol vía oral frente a vía vaginal en gestantes a término con un score de Bishop ≤ 4, y encontraron que el uso del fármaco por vía vaginal se asocia con una inducción exitosa, menor intervalo de inducción y un menor porcentaje de fallas en comparación con la vía oral. Esto puede explicarse por la absorción más rápida que tendría la vía intravaginal (3). Otros estudios reportan el uso de misoprostol vía oral; comparado con la vía intravaginal, se asocia con menos anormalidades de la contractilidad, pero que requieren un aumento del uso de oxitocina (2).
Comentarios sobre el artículo "Análisis de costo-efectividad del uso de calcio más ácido linoleico para la prevención de la hipertensión inducida por el embarazo en mujeres con riesgo en Colombia"
Authors: Sanín Blair José Enrique
Published: November 2019

Medellín, 28 de noviembre de 2012 Doctor Hernando GaitánEditor Revista Colombiana de Obstetricia y GinecologíaEn la edición de la Revista Colombiana de Obstetricia y Ginecología, vol. 63, No. 3 (julio-septiembre de 2012) salió publicado el artículo de Martín Romero-Prada et al., titulado "Análisis de costo-efectividad del uso de calcio más ácido linoleico para la prevención de la hipertensión inducida por el embarazo en mujeres con riesgo en Colombia", el cual me llamó la atención por el tipo de análisis económico en salud que presenta, que es poco frecuente en la revista, y por referirse a un problema de salud pública en Colombia, tal como son los trastornos hipertensivos del embarazo. El artículo presenta en mi opinión algunas ligerezas que vale la pena aclarar:A lo largo del manuscrito científico se presentan inconsistencias con el término hipertensión inducida por el embarazo (HIE), que no es utilizado en la literatura científica desde finales de los años noventa debido a que ocasiona confusión, pues se engloban en una misma enfermedad diferentes patologías, con distinta etiología y disímil pronóstico materno y perinatal. Los autores, en la introducción del artículo, referencian este término como el sugerido por el "Report of the National High Blood Pressure Education Program Working Group on High Blood Pressure in Pregnancy" (1), sin embargo, en este consenso norteamericano, contrario a lo expresado por los autores, lo que se intentó fue evitar el término HIE y tratar de involucrar y categorizar los trastornos hipertensivos durante la gestación. La etiología de la preeclampsia temprana o tardía, la hipertensión gestacional, la eclampsia y la hipertensión arterial crónica comparten algunas características, pero los fenómenos etiológicos, la progresión de la enfermedad y la severidad son diferentes, y hoy por hoy plantear una investigación, así sea desde el punto de vista económico, sin tener claramente definido el problema, plantea dificultades metodológicas y conclusiones erróneas, como al final lo señalan los autores.
INCLUSÃO DE ALUNOS COM DEFICIÊNCIA EM ESCOLAS PÚBLICAS: OLHARES DOS BOLSISTAS DO PIBID DE EDUCAÇÃO FÍSICA
Authors: Ferreira Karen Menegaro , Feltrin Simone Das Graças Nogueira
Published: November 2019

RESUMO: A finalidade deste artigo é apresentar os resultados de uma pesquisa realizada  com os bolsistas do Programa Institucional de Bolsas de Iniciação à Docência (PIBID) de Educação Física, apontando suas percepções  relacionada à inclusão escolar onde desenvolvem suas ações. O PIBID é um programa oferecido pelo governo federal, que proporciona aos bolsistas, vivência nas escolas públicas. A UNESC conta com nove subprojetos, dentre eles o subprojeto de Educação Física que possui 45 bolsistas, somente 38 participaram da pesquisa e 07 não participaram, pois os mesmos haviam entrado há pouco tempo no subprojeto. A metodologia utilizada é uma pesquisa de campo com a abordagem qualitativa e quantitativa, na qual foi aplicado um questionário com perguntas abertas e fechadas. Logo após, foi realizado a análise dos dados coletados o que nos permitiu constatar dos 38 bolsistas que participaram da pesquisa 66% responderam que na escola onde desenvolvem suas ações, possuem alunos com deficiência matriculados frequentando a escola e que, a inclusão tem acontecido nas aulas de educação física. É importante salientar, que este estudo é fruto do Trabalho de Conclusão de Curso de Educação Física e para que a pesquisa se efetivasse  a mesma foi aprovada pelo Comitê de Ética, sob o Parecer nº 1.313.162 /2015.
OBSERVANDO AULAS DE BIOLOGIA EM UMA ESCOLA NO EXTREMO SUL CATARINENSE
Authors: Borghezan Juliana , Martins Miriam Da Conceição
Published: November 2019

A presente pesquisa teve por objetivo compreender o processo de ensino-aprendizagem na disciplina de Biologia. Ocorreu no primeiro semestre de 2017, com uma turma de segundo ano do ensino médio, observaram-se seis aulas, no período matutino. A Escola de Educação Básica Toneza Cascaes pertence ao município de Orleans/SC. Foram envolvidos no estudo vinte oito (28) alunos. A metodologia utilizada foi qualitativa, como instrumento de pesquisa aplicamos um questionário, contendo questões objetivas e subjetivas. A partir dos resultados, constatamos que os estudantes possuem algumas dificuldades na disciplina, pelos conteúdos e forma de ensino. E que escola precisa de laboratório e biblioteca equipados. Entretanto, considerou-se uma experiência enriquecedora, pois a observação estabeleceu um primeiro contato com os alunos, professores e escola, oportunizando a adaptação a esse novo ambiente até então desconhecido na prática.
EVASÃO ESCOLAR: AS CAUSAS E AS CONSEQUÊNCIAS DE UMA NEGLIGÊNCIA SOCIAL
Authors: Leal Nilma Maria de Oliveira
Published: November 2019

O presente estudo tem por objetivo apresentar uma discussão acerca da evasão escolar, apontando suas causas, elucidando as possíveis consequências individuais e sociais, e abrindo pontos discursivos acerca de quais medidas podem ser tomadas de acordo com as demandas aplicadas nessa temática. Partindo de uma análise bibliográfica, foram selecionados teóricos que discutem a relação da evasão escolar com a decadência estrutural do país, buscando encontrar pontos de conexão entre o posicionamento social e as desistências ocorridas no contexto educacional. Trata-se de uma visão ampla sobre a atual posição de jovens e adultos não escolarizados no contexto educacional de ensino-aprendizagem.
Problematyka podziału majątku polikwidacyjnego spółki z o.o. ze szczególnym uwzględnieniem zagadnienia wydania jego składników w formie rzeczowej w świetle prawa podatkowego
Authors: Tychmańska Aleksandra
Published: November 2019

W artykule zostało przeanalizowane zagadnienie podziału majątku polikwidacyjnego spółki z o.o. pomiędzy jej wspólników, ze szczególnym uwzględnieniem problematyki wydania jego składników w formie rzeczowej. Przyczynkiem do analizy niniejszego zagadnienia była niejednolita linia orzecznicza sądów administracyjnych w zakresie uznania, czy czynność wydania majątku polikwidacyjnego w formie rzeczowej prowadzi do powstania po stronie spółki przychodu. Autorka skupia się zarówno na regulacjach prawa podatkowego, jak też prawa handlowego oraz zasad rachunkowości w odniesieniu do tej kwestii.
Algerian Indigenous Dog: Hemato-biochemical Profile in Healthy and Gastroenteritis Diseased Case
Authors: Nadia Hafid
Published: November 2019

The purpose of this study is firstly, to establish the haemato-biochemical reference values ​​of the indigenous canine breed in Batna area of Algeria as related to the gender effect. For this reason, 20 apparently healthy local dogs were used. A complete blood count and the serum biochemical parameters analysed here remained mostly within the physiological reference intervals. The effect of sex was only observed in the platelet count, which is higher in female dogs, whereas the creatinine level is higher in male dogs. The second part is devoted to evaluating the haemato-biochemical parameters in dogs with moderate to severe gastroenteritis infections. A total of 37 diseased dogs were selected and classified into two groups – diseased vaccinated dogs and diseased unvaccinated dogs – to establish the haemato-biochemical parameters. Haemato-biochemical investigation shows significant alteration in diseased unvaccinated dogs than other groups.