bluuebunny/crossref_metadata_2025 huggingface dataset:
Pemberian Laktoferin Sapi Meningkatan Bobot Badan dan Tidak Mengubah Rasio Leukosit Anak Babi Landrace
Authors: Pramudita Ghina Monita , Mahardika I Gusti Ngurah Kade , Suartini I Gusti Ayu Agung
Published: March 2022

Penelitian ini bertujuan untuk mengetahui pengaruh pemberian pakan yang ditambahkan laktoferin sapi terhadap berat badan dan leukosit anak babi Landrace. Penelitian dilakukan pada peternakan komersial di Desa Yeh Gangga, Kecamatan Sudimara, Kabupaten Tabanan. Sebanyak 12 anak babi Landrace dari tiga induk yang berbeda digunakan sebagai sampel, dengan pembagian dua kelompok, yaitu kelompok kontrol dan perlakuan. Kelompok kontrol tidak diberikan perlakuan. Kelompok perlakuan diberikan laktoferin sapi selama 7 hari dengan pemberian satu kali dalam satu hari. Penimbangan berat badan anak babi Landrace dilakukan setiap lima hari, kemudian data dianalisis dengan Student’s T-test. Hasil analisis data periode penimbagan berat badan anak babi umur 10 – 35 hari berpengaruh nyata (P<0,05). Pengabilan darah dilakukan pada post perlakuan kemudian diuji dengan uji hematologi. Data yang diperoleh dianalisis menggunakan Student’s T-test. Hasil penelitian menunjukkan bahwa rerata diferensial leukosit tidak berbeda nyata (P>0,05) antara kelompok kontrol dan kelompok perlakuan. Masing-masing komponen leukosit pada kelompok kontrol maupun kelompok perlakuan berada pada rentang nilai normal. Rerata total leukosit anak babi pasca pemberian laktoferin tidak berbeda nyata (P>0,05) antara kelompok kontrol dan kelompok perlakuan.
Y llegaron las panzonas: Ensayo regresivo sobre la ganadería bovina. en Tabasco, 2015-1949.
Authors: Marín Olán Pablo
Published: March 2022

El presente trabajo es un intento de explicar históricamente el cierre de las principales empresas ganaderas tabasqueñas que otrora fueran un ejemplo nacional. Para ello se hace uso del método regresivo, con la intención de encontrar un punto de partida que permita construir una periodización histórica que vaya más acorde a los procesos y eventos que viven las sociedades agrícolas. El resultado de emplear este análisis regresivo es la corroboración empírica de un modelo de integración vertical en la industria de carne de bovino. Lo anterior podría ayudarnos a ponderar las secuelas de este modelo de mercado que va desde la pérdida del germoplasma bovino, hasta la especialización del sureste mexicano como un nicho para la producción barata de becerros.
Idea wspaniałego antropocenu: wrogie przejęcie czy antropodycea?
Authors: Bińczyk Ewa
Published: March 2022

The idea of the great Anthropocene: Hostile takeover or anthropodicy?The article discusses claims and postulates of the so-called An Ecomodernist Manifesto, signed in 2015 by such intellectuals as Ted Nordhaus, Michael Shellenberger, Ruth de Vries or David W. Keith. Ecomodernists or ecopragmatists, as they liked to be called believe in the possibility of creating the great or at least the good Anthropocene. Their theses are subsequently confronted in the text with a strong critical response articulated in A Degrowth Response to An Ecomodernist Manifesto, published in the same year. The presentation of the discussion is additionally enriched by the analysis of other arguments, invoked by such scholars as an Australian economist Clive Hamilton, an American ecosocialist Ian Angus, an Irish expert of environmental security Simon Dalby and a French sociologist and philosopher Bruno Latour. The aforementioned researchers interpret the ecomodernist idea of the good Anthropocene as un unjustified techno-optimism, as an attempt to hijack the idea of the Anthropocene, as a kind of highly controversial anthropodicy, and as groundless technological or neoliberal optimism upheld by the privileged groups in the developed world.
Usłyszeć antropocen. O dźwiękowych reprezentacjach zmiany klimatu
Authors: Tańczuk Renata
Published: March 2022

To hear the Anthropocene: On sound representations of climate changeTaking up the problem of climate change, Nicholas Mirzoef, in his book How to See the World, argued that we should make it less abstract and that we need a new mode of visual thinking, adequate to the Anthropocene. The Anthropocene can also be heard and the anthropogenic impacts can have an audible dimension as well. This article provides reasons for using sounds as a medium communicating the ongoing changes and lays out different kinds of sound representations of the anthropocene demonstrated by practitioners and theoreticians of acoustic ecology and sound artists B. Krause, D. Dunn. Recordings of the environment and works by sound artists are given consideration with respect to their affective potential, their ability to influence us and our emotions, to shape a more responsible attitude to the environment that we inhabit together with the nonhuman agents.
Kara ograniczenia wolności w systemie środków reakcji karnej. Rozważania aksjologiczne i polityczno-kryminalne
Authors: Zalewski Wojciech
Published: March 2022

Restriction of liberty in the system of criminal remedies. Axiological and political-criminal reflectionsThe beginning of the 21st century has been marked by technicisation of sentencing, development of biometry, managerialism in sentencing and privatisation of sentence en­forcement. As if on the margins of the main process there are attempts to find alternatives to the old paradigm, especially in the form of remedial justice. The present paper is an an­alysis of the axiological assumption, international experiences as well as selected foreign and Polish solutions concerning remedies based on local community work. Experiences with applying this form of sentencing demonstrate its advantages: staying in touch with one’s milieu, self-discipline, flexible sentencing and costs of organisation. If the remedy is to be perceived as a form of punishment, it is important for the work performed by the sentenced offenders to be genuinely beneficial to society.
Kradzież karty uprawniającej do podjęcia pieniędzy z automatu bankowego art. 278 § 5 k.k. jako przykład kryminalizacji na przedpolu czynu zabronionego
Authors: Tyburcy Tomasz
Published: March 2022

The theft of a card authorizing withdrawing money from a cash machine Art. 278 § 5 of the Criminal Code as an example of criminalization bordering on an offense substitutiveIn contrast to the classical theft this offense has not been partially-decriminalized. The subject of the crime cannot be a card that entitles the owner to make payment, since it constitutes “other means of payment” within the meaning of art. 115 § 9 C.C.; and as such is the subject of the theft of another person movable property Art. 278 § 1 C.C..
Ogólne dyrektywy wymiaru kary za wykroczenia
Authors: Kania Agnieszka
Published: March 2022

General directives of the sentencing for infractionsThis study focuses on the issue of general directives of the sentencing for infractions. In that regard, the study not only makes a reference to the statutory wording of the said regulations but also draws attention to the traditional interpretative controversies related to that issue. Furthermore, the article presents that view that although translating prescriptive provisions into practice is not an easy task, the existence of the said regulations prevents the adjudicating body from crossing the borders of discretion.
Judicial sentencing of minor and juvenile offenders. Remarks in the context of the Polish Criminal Code
Authors: Kania Agnieszka
Published: March 2022

This article addresses selected issues related to the status of the minor and the ju­venile from the perspective of criminal liability. While analyzing the issues indicated in the title references have been made not only to Article 10 § 2 and 3 of the Criminal Code, but also to Article 54 of the Criminal Code, which contains two specific directives of the judicial imposition of asentence on juvenile offenders.
A few remarks on federal crime of money laundering in the Unites States
Authors: Płońska Anna
Published: March 2022

The phenomenon of money laundering is, generally speaking, the practice of using a business to conceal cash or other assets that are the products of other criminal activ­ity. The money laundering legislation was developed from perceived difficulties with enforcement of the currency transaction reporting requirements of the Bank Secrecy Act BSA. In 1986 the US Congress for the first time attempted to define and criminal­ized anactivity nowadays commonly known as money laundering. This paper presents some of the most essential aspects of federal crime of money laundering in the Unites States, indicating such types as: laundering of monetary instruments, engaging in mon­etary transactions in property derived from specified unlawful activity, and unlicensed money laundering business, respectively stated under 18 U.S.C. §§ 1956, 1957, and 1960.
Relación entre los factores de riesgo ocupacional y la intención de rotación de personal en la Corporación Peruana de Productos Químicos – Sede Agustino, Lima: 2020
Authors:   ,   Universidad San Ignacio de Loyola, Guzmán Mendoza Geraldine Stefani
Published: March 2022

La investigación tiene como objetivo analizar los factores de riesgo ocupacional en la intención de rotación de personal en la empresa CPPQ, Lima – 2020. Por este motivo, se analizó usando la metodología cuantitativa, teniendo como punto de partida el enfoque no experimental, transversal, correlacional, teniendo un total 1,200 trabajadores, pero con una población de 85. Entre las conclusiones, se analizó que existe una relación siendo principalmente un problema relacionado al sueldo (psicosocial), la cual debe ser tratado de manera efectiva debido a la carga de trabajo (condiciones laborales). Adicionalmente, se determinó que la variable intención de rotación y los factores de riesgos ocupacionales se relacionan entre sí, teniendo consecuencias el factor químico (0.578) y psicosocial (0,377) como los principales problemas. Entre las recomendaciones, se puede decir, se debe realizar una evaluación desde el punto de vista de clima organizacional, ya que desde el aspecto psicosocial es el aspecto que ha condicionado en primer lugar su acción en la intención rotación (sueldos) y analizar el tema de la afectación química a los trabajadores (analizar otras opciones de abastecimiento en la compra de productos que no dañen a los trabajadores).
Dversifikasi Kue Kering Kekinian Berbahan Baku Beras Merah Lokal dan Sagu
Authors: Sari Noor Mirad , Violet Violet , Nisa Khairun , Manipa Ayu
Published: March 2022

The Yasinan Arraudah group consists of women who work as traders, catering services, and housewives. The impact of the Covid-19 pandemic has affected partners, namely a decrease in sales turnover until the closure of businesses for members who work as traders or catering services. The implementation team of the Community Partnership Program provides the right solution for business opportunities in the new normal era, namely making healthy pastries made from brown rice flour and sago flour. The selection of local brown rice flour and sago flour to support the government's efforts in accelerating the diversification of food consumption based on local resources and reducing dependence on wheat flour. The problem faced by partners is the lack of knowledge about how to make modern pastries from local brown rice and sago which is healthy and hygienic and does not have the equipment, availability of raw materials, packaging methods and product marketing methods. The method of activity is in the form of counseling, training in making pastries, assistance to activity partners and program evaluation. The results of the counseling and training activities showed that 80% of the participants were able to make modern pastries made from brown rice and sago, namely Nastar Beras Merah, Cookies Susu Wijen, Kuker Sagu, and Selai Cookies. The outputs produced in the Community Partnership Program activities are in the form of contemporary pastries, publications in mass media, activity videos on YouTube and scientific articles.Keywords: contemporary pastries, food diversification, local brown rice, and sago
Uji Cara Aplikasi PGPR dalam Menekan Kejadian Penyakit Antraknosa pada Tanaman Cabai Hiyung di Lahan Rawa
Authors: Cholis Fahmi Rizali , Budi Ismed Setya , . Mariana
Published: March 2022

Chili Hiyung is a local chili variety typical of South Kalimantan. At this time began to be exposed to a lot of anthracnose disease. Control using pesticides needs to be avoided by finding more convenient control methods. Area-friendly disease control includes using PGPR (Plant Growth Promoting Rhizobacteria). The use of PGPR for chili plants in the swamp land of Hiyung village has not been studied, meanwhile its potential has been tested on several other plants. This research aims to identify the effect of PGPR in suppressing anthracnose disease in Chili Hiyung in the swamp land of Hiyung Village. The design used was a single aspect Completely Randomized Design (CRD) based on 4 (four) treatments, namely the leak, spray, or spray and leak methods. The results of the research show that the PGPR application does not affect the incidence of anthracnose disease in Hiyung chili plants in Hiyung village. But the PGPR application can increase plant size and fruit weight per branch.
Pengaruh Tanaman Refugia Kenikir (Cosmos caudatus) dan Marigold (Tagetes erecta L.) terhadap Serangan Lalat Buah (Bactrocera spp.) pada Tanaman Cabai Merah Besar (Capsicum annuum L.) di Lahan Gambut
Authors: Arianto Feri , Salamiah Salamiah , Soedijo Samharinto
Published: March 2022

Cabai merah besar (Capsicum annuum L.) merupakan komoditas yang sangat dibutuhkan, khususnya dalam industri makanan dan kebutuhannya sering meningkat. Kebutuhannya yang meningkat tersebut berbanding terbalik dengan ketersediaan cabai yang tidak dapat terpenuhi. Penyebabnya antara lain adanya kendala serangan lalat buah (Bactrocera spp.) yang selalu terjadi pada tanaman cabai. Gejala yang ditimbulkan berupa adanya lubang kecil pada buah cabai, buah rontok dan terdapat larva di dalam buah. Pengendalian yang sering dilakukan adalah dengan menggunakan insektisida kimia yang dapat mengakibatkan pencemaran lingkungan. Salah satu solusinya adalah dengan pemanfaatan tanaman refugia. Penelitian ini dilakukan untuk mengetahui pengaruh tanaman refugia terhadap serangan lalat buah pada tanaman cabai dan efektifitasnya tanaman kenikir (Cosmos caudatus) dan marigold (Tagetes erecta L.) dalam menekan serangan lalat buah pada tanaman cabai. Rancangan yang digunakan adalah Rancangan Acak Kelompok (RAK) dengan 4 perlakuan, kontrol (T0), tanaman kenikir dan marigold ditanam bersama cabai (T1), tanaman kenikir ditanam bersama cabai (T2), tanaman marigold ditanam bersama cabai (T3) dan diulang sebanyak enam kali. Hasil pengamatan, tanaman refugia berpengaruh terhadap serangan lalat buah. Tanaman refugia jenis marigold, intensitas serangan lalat buah mencapai 6,01% dan 19,30%, sedangkan jenis kenikir intensitas serangannya mencapai 13,61% dan 33,61%.
Local Energy Markets in Action: Smart Integration of National Markets, Distributed Energy Resources, and Incentivisation to Promote Citizen Participation
Authors: Klement Peter , Brandt Tobias , Schmeling Lucas , de Bronstein Antonieta Alcorta , Wehkamp Steffen , Penaherrera Vaca Fernando Andres , Lanezki Mathias , Schönfeldt Patrik , Hill Alexander , Katic Nemanja
Published: March 2022

Since the Paris Agreement in 2016, the goals of limiting climate change and moving toward climate resilience stand. With a share of about \SI{80}{\percent} of global \ce{CO2} emissions, the energy sector is an essential driver for these goals. A shift to low-carbon energy production and a decentralized system for more efficient energy transmission distribution is necessary. In this paper, we present our work on Modeling of Power Exchanges, Algorithms for \ac{LEM}, Competitiveness of \ac{CHP} and Energy Feedback Devices. The study was conducted considering technical, economic, social and regulatory framework. For easy integration into energy simulations or a \ac{DEMS}, a model for power exchanges was created that allows flexible input or deterministic price patterns. The algorithm handles the clearing of an \ac{LEM} by a district aggregator using limit orders with the goal of increasing the share of locally consumed electricity using economic incentives. An investigation was conducted into the operation of flexible \acp{CHP} in low-carbon power systems to balance the volatility of renewable energy. An energy signal light was developed as an energy feedback device, which is integrated into the \ac{DEMS} in a living lab and allows individual configuration. In summary, the results presented should be compared with those of other research approaches in the future and require qualitative and quantitative evaluation.
A Generic Scalable DFT Calculation Method for Vectors and Matrices Using Matrix Multiplications
Authors: Khan Abdullah Aman
Published: March 2022

Computation of Discrete Fourier Transform (DFT) is a challenging task. Especially, on computational machines/embedded systems where resources are limited. The importance of Fourier Transform (FT) cannot be denied in the field of signal processing. In this paper, we propose a technique that can compute Discrete Fourier Transforms for a matrice or vector with the help of matrix multiplication. Moreover, we discuss the trivial methods used for computation of DFT along with methods based on matrix multiplication used to compute discrete Fourier Transform. Furthermore, we explain the shortcomings. Our method can help in the calculation of a Discrete Fourier Transformation matrix by truncation of values from our proposed generic method which can help in computing DFT of varying lengths of vectors. On computing machines and programming environments, having support for matrix multiplication, our proposed methodology can be implemented.
Mitophagy eliminates the accumulation of SARM1 on the mitochondria, alleviating programmed axon death in acrylamide neuropathy
Authors: Wang Shuai , Yong Hui , Zhang Cuiqin , Kang Kang , Song Mingxue , Yang Yiyu , Huang Zhengcheng , Wang Shu’e , Ge Haotong , Zhao Xiulan , Song Fuyong
Published: March 2022

Sterile-α and toll/interleukin 1 receptor motif containing protein 1 (SARM1) is the defining molecule and central executioner of programmed axon death (also known as Wallerian degeneration). Although it has been confirmed to have a mitochondrial targeting sequence and can bind to and stabilize PTEN-induced putative kinase 1 (PINK1) for mitophagy induction, deletion of the mitochondrial localization sequence disrupts SARM1 mitochondrial localization in neurons but does not alter its ability to promote axon degeneration after axotomy. The biological significance for mitochondrial localization of SARM1 remains elusive. Here, we demonstrated that the SARM1-dependent axonal destruction pathway was involved in acrylamide (ACR) neuropathy in vivo and in vitro, a moderate Wallerian-like programmed axonal death process. The up-regulated SARM1 accumulated on mitochondria, which interfered with mitochondrial dynamics and activated PINK1-mediated mitophagy. Importantly, rapamycin (RAPA) intervention eliminated mitochondrial accumulated SARM1 and partly attenuated ACR neuropathy. Thus, mitochondrial localization of SARM1 contributes to its clearance through the SARM1-PINK1 mitophagy pathway and mitophagy, in turn, negative feedback inhibits axonal degeneration. Mitochondrial localization of SARM1 is complementary to the coordinated activity of the pro-survival factor, nicotinamide mononucleotide adenyltransferase 2 (NMNAT2), and SARM1, and is part of the self-limiting molecular mechanisms of programmed axon death.
Synthesis of gold nanowires using laser ablation for improved colon biosensor
Authors: Fakhri Makram A , Ali Hiyam , Salim Evan T. , Hashim Uda
Published: March 2022

Gold nanowires (Au NWs) were prepared using 9 nsec ND-YAG laser ablation in Ethanol employing 532 nm and 1.064 nm wavelengths. The colloidal solution was investigated depending on the X-ray diffraction (XRD) technique, the photoluminescence (PL) spectra, and Ultraviolet-Visible (UV-VIS) spectroscopy. The FESEM results reveal the formation of smaller Nano rode size at Second-harmonic generation (SHG) wavelength where found to be about (30 nm at wavelength 532 nm and 0.44 μm at 1064nm). Using Finite Element Analysis the simulation of photonic crystal fiber (PCF) as biosensors were done, depended on surface plasmon resonance (SPR) phenomenon using COMSOL Multiphysics program. The hollow core-photonic crystal fiber (HC-PCF) HC-800 was thus overfilled with (water). The confinement loss (CL) of the fundamental mode for the proposed PCF with and without the gold nanoparticles was calculated, we observe without gold NPs the CL at the water and Colon tissue about (1.08E+03, 5.46E+02) dB/m, while at use the deposited PCF with gold NPs the results ensured the decrease more than in the confinement loss at the water and Colon tissue about (1.01E+03, 3.16E+02) dB/m with a clear shift toward higher wavelengths.
DNA-Based Species Identification of Shark Fins Traded in Thai Markets.
Authors: Klangnurak Wanlada , Arunrugstichai Sirachai , Manopawitr Petch , Krajangdara Tassapon
Published: March 2022

Shark fins are among the most highly prized seafood products in the world with massive consumption in Asia over the past several decades. The demand for shark fins is a major driver of the enormous population declines of elasmobranchs that are generally vulnerable to overexploitation. This study aims to better understand the species composition of shark fin products in Thailand and their conservation statuses by using DNA-based species identification. Various types and sizes of shark fins were collected from 4 locations in Thailand. DNA barcoding method based on a fragment of the cytochrome c oxidase subunit I (COI) gene was applied to species identification. The optional pathway to report any amplified samples to the possible lowest taxonomy level are presented. Fins from at least 13 shark species were found among the samples we collected from Thailand’s markets. The spottail shark (Carcharhinus sorrah) and the night shark (Carcharhinus signatus) were the two dominant species presented in this study. The conservation status listed in the IUCN Red List and Thailand Red Data were reported for identifiable species. Size-species specification was also discussed. Species composition reported in shark fin products potentially helps indicate the appropriate conservation action and increases awareness from monitoring the trade in elasmobranch products.
Global change impacts a threatened species through alteration of predator-prey dynamics
Authors: Labadie Guillemette , Hardy Clément , Boulanger Yan , Vanlandeghem Virginie , Hebblewhite Mark , Fortin Daniel
Published: March 2022

Although global change can reshape ecosystems by triggering cascading effects on food webs, indirect interactions remain largely overlooked. Climate- and land use-induced changes on landscape cause shifts in vegetation composition, which affect entire food webs. We used simulations of forest dynamics and movements of interacting species, parameterized by empirical observations, to predict the outcomes of global change on a large-mammal food-web in boreal forest. We demonstrate that climate- and land use-induced changes of forest landscapes exacerbate asymmetrical apparent competition between moose and threatened caribou populations, through wolf predation. While increased prey mortalities came from both behavioural and numerical responses, indirect effects from numerical responses had an overwhelming effect. The increase in caribou mortalities was exacerbated by the cumulating effects of land-use over the short term and climate change impacts over the long-term, with higher impact of land-use. Indirect trophic interactions will be key to understanding community dynamics under global change.
The performance of pretreatment MR-based radiomics in Recombinant human endostatin plus concurrent chemoradiotherapy response prediction in nasopharyngeal carcinoma: A primary study
Authors: Huang Lixuan , Yang Zongxiang , Kang Min , Ren Hao , Jiang Muliang , Tang Cheng , Hu Yao , Shen Mingjun , Lin Huashan , Long Liling
Published: March 2022

Background: Antiangiogenic therapy may transiently “normalize” the tumor vasculature to increase the effect of chemoradiotherapy. The present study confirmed the combination of antiangiogenic therapy with chemoradiotherapy provides a promising strategy for the improvement of the prognosis of nasopharyngeal carcinoma(NPC) patients. Recombinant human endostatin (RHES) is a new type of antiangiogenic agent. Radiomics is a new method to study tumor heterogeneity, and it can evaluate tumor heterogeneity and biological characteristics by screening these features and constructing models. This study was aimed at investigating the capability of an MRI radiomics model based on pre-treatment texture features in predicting the efficacy of RHES + concurrent chemoradiotherapy (CCRT) for NPC.Methods:In total, we retrospectively enrolled 65 patients newly diagnosed as having NPC and treated with RHES + CCRT. 144 texture features were extracted from the MRI before RHES+CCRT treatment of all the NPC patients. The maximum relevance minimum redundancy (mRMR) method was used to remove redundant, irrelevant texture features, and calculate the Rad score of the primary tumor. Multivariable logistic regression was used to select the most predictive features subset, and prediction models were constructed, which included radiomics models, clinics models, and combined models. The performance of the three models in predicting the early response of RHES + CCRT for NPC was explored.Result:The diagnostic efficiency of combined model and radiomics model in distinguishing between the groups was found to be moderate. The area under the curve (AUC) of the combined model and radiomics model was 0.74 (95% CI: 0.62–0.86) and 0.71 (95% CI: 0.58–0.84), respectively, with both being higher than the AUC of the clinics model (0.63, 95% CI: 0.49–0.78). Compared with the pure radiomics model, the combined model showed marginally improved diagnostic performance in predicting RHES + CCRT treatment response. The accuracy of combined model and radiomics model for RHES + CCRT response assessment in NPC were higher than those of the clinics model (0.723, 0.723 vs. 0.677). Conclusion:The pretreatment MRI based radiomics can predict RHES + CCRT response in patients with NPC with a better accuracy than the clinics model.
Comparison of the Gastrointestinal Microbiome in Billroth I and Roux-en-Y Reconstructions After Distal Gastrectomy
Authors: Imai Yoshiro , Lee Sang-Woong , Sakaguchi Shoichi , Kato-Kogoe Nahoko , Taniguchi Kohei , Omori Michi , Tanaka Ryo , Honda Kotaro , Osumi Wataru , Nakano Takashi , Ueno Takaaki , Uchiyama Kazuhisa
Published: March 2022

Few reports exist regarding changes in gastric microbiota after distal gastrectomy; to our knowledge, none examined changes following reconstruction. This study aimed to compare the gastric microbiota following Billroth I and Roux-en-Y reconstructions after distal gastrectomy. We enrolled 71 gastrectomized patients with gastric cancer; 31 and 40 underwent Billroth I and Roux-en-Y reconstructions, respectively. During upper gastrointestinal endoscopy, gastric fluid was collected immediately before and 6 months after distal gastrectomy. Deoxyribonucleic acid isolated from each sample was evaluated using 16S ribosomal ribonucleic acid metagenomic analysis. Analysis revealed that the gastric microbiota’s species richness (expressed as the alpha diversity) was significantly lower after than before distal gastrectomy (operational taxonomic units, p = 0.001; Shannon index, p = 0.03). The interindividual diversity (beta diversity) was significantly different before and after distal gastrectomy (unweighted UniFrac distances, p = 0.04; weighted UniFrac distances, p = 0.001; Bray–Curtis, p = 0.001). Alpha and beta diversity were not significantly different between Billroth I and Roux-en-Y reconstructions (observed operational taxonomic units, p = 0.58; Shannon index, p = 0.95; unweighted UniFrac distances, p = 0.65; weighted UniFrac distances, p = 0.67; Bray–Curtis, p = 0.63). Our study demonstrated significant differences in gastric microbiota diversity, composition, and community before and after distal gastrectomy but no difference between Billroth I and Roux-en-Y reconstruction after distal gastrectomy.
Implementation of Back At work After Surgery (BAAS): a feasibility study of an integrated pathway for improved return to work after knee arthroplasty
Authors: Strijbos Daniel Otto , Sluis Geert van der , Boymans Tim A.E.J. , de Groot Stephan , Klomp Simon , Kooijman Carolien M. , Reneman Michiel F. , Kuijer Paul P.F.M.
Published: March 2022

Purpose: Optimizing return to work after knee arthroplasty is becoming more important because of the growing incidence of KA among workers and poor return to work outcomes. The purpose of this study is to investigate the feasibility of Back At work After Surgery (BAAS): an integrated clinical pathway for return to work after knee arthroplasty. Method: Working patients who received unicompartmental knee arthroplasty (UKA) or total knee arthroplasty (TKA) between January 2021 and November 2021, younger than 65 years and motivated to return to work were eligible to participate. Feasibility was investigated on five domains: reach, dose delivered, dose received, fidelity and patients’ attitudes. These outcomes were obtained by a patient-reported questionnaire and an interview with the occupational case manager and medical case manager.Results: Of the eligible 29 patients, eleven were willing to participate (response rate 38%; due to travel distance to and from the hospital). The dose delivered was between 91 and 100%, except information given about return to work from the orthopedic surgeon which was 18%. The dose received was 100%. For fidelity, case managers reported nine shortcomings for which five solutions were mentioned. In terms of patients’ attitude, all patients were satisfied and one patient mentioned an improvement. Conclusions: In terms of reach, participation was low: only 29%. The BAAS clinical pathway seems feasible based on dose delivered, dose received, fidelity and patient attitudes. The next step is to assess the effectiveness of the BAAS clinical pathway for return to work.
Willingness to Join and Pay Social Health Insurance and Associated Factors Among Public Sectors Workers in Didu Woreda, South West Ethiopia, 2018
Authors: Regassa Zelalem , Negera Ebissa , Silashi Tesfaye , Kaba Zalalem
Published: March 2022

BackgroundSocial health insurance is a form of healthcare financing mechanism for raising and pooling funds to finance and manage health services to attain universal health coverage. Cost-sharing between beneficiaries and governments is critical to achieving universal health care coverage. To address this, Ethiopia is currently introducing social health insurance.ObjectiveTo assess the willingness and associated factors to join and pay social health insurance among public sectors workers in Didu woreda, southwest Ethiopia,2018MethodologyA cross-sectional study was conducted from April 15–30, 2018 on 280 public sector workers of Didu Woreda. Stratified and simple random sampling techniques were used, and data were collected using a structured interviewer-administered questionnaire. Binary logistic regression analysis was used to compute crude odd ratio with its 95% confidence interval to test the associations between dependent and independent variables and a P-value of 0.05 with a confidence interval of 95% was used to declare the level of statistical significance.Results280 public sectors workers participated, with a response rate of 98.2%. About 33.6% of the public servants had never heard of any type of health insurance scheme. However, 47.5% of them were willing to join for the suggested insurance scheme from these about 58% of those who were willing to join are willing to pay 3%of their monthly salary that was proposed. Willingness to join was significantly associated with the age of respondents, marital status, job description, how much paid, the satisfaction of the respondents, and previous history of borrowing money for the medical service fees.Conclusionwillingness to join and pay in this study was found to be 47.5% and 58% respectively. Therefore, adequate awareness creation and discussion should be made with all employees.
Geochemical analysis of the Late Ordovician–early Silurian black shales from the Xindi No.2 well in the Upper Yangtze area, South China: Implications for provenance, palaeoclimate and palaeoenvironmental change
Authors: Men Xin , Mou Chuanlong , Ge Xiangying
Published: March 2022

The Ordovician-Silurian transition was a critical period in geological history, during which profound changes in climatic, biotic, and oceanic conditions occurred. To explore the provenance, palaeoclimate, and palaeoredox conditions in the Sichuan Basin during the Late Ordovician- early Silurian interval, we conducted a mineralogical and geochemical analysis of three formations (Wufeng, Guanyinqiao and Longmaxi formations) encountered in the Xindi No.2 well. The ternary diagram of Al2O3-(CaO*+Na2O)-K2O and the bivariate diagram of La/Th-Hf and La/Yb-∑REEs indicate that the provenance of these formations is mainly from felsic igneous rocks. The La-Th-Sc, Th-Co-Zr/10, and Th-Sc-Zr/10 ternary diagrams and two multidimensional diagrams reveal that the samples in the study area mainly originated from a collisional setting, presumably due to an active continental margin. The chemical index of alteration (CIA) values indicate that the intensity of chemical weathering in the source area was weak to moderate. The CIA values in the lower part of the Wufeng Formation and Longmaxi Formation are relatively high (67.48-73.57), indicating that the climate was warm and humid during deposition. In contrast, the CIA value declined rapidly from the upper part of the Wufeng Formation (Metabolograptus.extraordinarius zone) to the Guanyinqiao Formation (Hirnantian stage; 58.30-64.66). During this period, the overall climate was cold and dry, but the data fluctuations show that the cold and dry climate was interrupted by a transient warm and humid climate. Palaeoredox indices (Mo concentrations and MoEF/UEF; U/Th, V/Cr, Ni/Co, and V/V+Ni values) fluctuate during the Late Ordovician- early Silurian, which were distinguished into four distinct parts, indicating two cycles of water column euxinia. The first cycle occurred during the accumulation of the Wufeng Formation, with bottom waters evolving from oxic-suboxic (part Ⅰ) to suboxic-anoxic (part Ⅱ). Regarding the period of accumulation of the Guanyinqiao Formation (part Ⅲ), most samples show low redox-sensitive trace element concentrations, suggesting oxic-suboxic conditions. The water column transitioned from oxic to euxinic in the late Hirnantian (at the base of the Longmaxi Formation). Strong euxinic bottom water persisted throughout the deposition of the Longmaxi Formation (part Ⅳ). Finally, the δ13Corg isotopic data constrain the timing of the Late Ordovician mass extinction and the evolution of temporal changes in the climatic and ocean redox conditions. Climatic fluctuations, coupled with oceanic anoxia, were likely responsible for the gradual end of the Late Ordovician biotic crisis.
Environmental extremes at high altitude drive clutch size patterns in a wide-ranging lizard
Authors: Deme Gideon Gywa , Wu Nicholas C , Sun Baojun , Xin Hao
Published: March 2022

Latitudinal patterns in reproductive output such as clutch size are linked to resource abundance and seasonal climate variation across taxa. Understanding if these patterns hold across local altitudinal gradients and within species can provide insight on key drivers of life-history evolution across scales. In this study, we examined geographical variations in clutch size and climate conditions in a wide-ranging lizard. We collected clutch data from ten populations of E. argus of varying elevation in China from both field observation and from the literature. A total of 369 clutches were obtained and generalized linear mixed-effects models were used to test the relationship between clutch size with body mass, habitat type, elevation, and climate conditions. Body mass strongly correlated with clutch size across all populations. Females from populations at high altitudes with low mean annual temperature and variability, and drier conditions had smaller clutches, while females at lower altitudes with higher mean temperatures and rainfall had larger clutch sizes. Poor climate conditions at high altitudes suggest fewer resources for females to invest in larger clutch size, likely due to reduced foraging and activity times, and growth under unfavourable conditions. These constraints match macroecological patterns of clutch size diversity in egg-laying taxa, suggesting local climate constraints can translate across scales to explain the diversity of reproductive output.
Biocompatible carbon dot decorated α-FeOOH nanohybrid for an effective fluorometric sensing of Cr (VI) in wastewater and living cells
Authors: Ghosh Bidisha , Roy Shubham , Bardhan Souravi , Mondal Dhananjoy , Saha Ishita , Ghosh Saheli , Basu Ruma , Karmakar Parimal , Das Kaustuv , Das Sukhen
Published: March 2022

This article reports the fluorometric detection of toxic hexavalent chromium Cr (VI)) in wastewater and Cr (VI) contaminated living cells using in-situ grown carbon quantum dots into the goethite (α-FeOOH) nano-matrix. The synthesized nano-hybrid shows enormous potential in determining the chromium contamination levels in various types of water samples. This selective fluorometric probe is enormously sensitive (LOD 81nM) towards hexavalent chromium, which makes it a dedicated chromium sensor. Moreover, the sensing mechanism has been assessed using Stern-Volmer’s equation and fluorescence lifetime experiments showing the simultaneous occurrence of photoinduced electron transfer and inner filter effect. This chromium sensor has also been employed to assess the contamination level in real-life industrial wastewater. The performance of this probe in real-life wastewater sample is quite commendable. Further, this biocompatible fluorometric probe has been used to demonstrate the in-vitro sensing of Cr (VI) in HeLa cells. The rapid detection mechanism of hexavalent chromium in living cells has been validated using theoretical docking simulations. Henceforth, this fluorometric sensor material could open new avenues not only in wastewater monitoring but also in biomedical applications.
Long- term safety of Eruca sativa leaf ethanolic extract on Male Rats
Authors: El-Gayar Hussam Ahmed , Derbala Safaa , Hamed Sahar , El-Demerdash Reda Soliman , Afifi Wael Mohamady , Emam Sameh Ibrahem Ahmed El , Edrees Gamal Mohamed
Published: March 2022

The present study was performed to evaluate the safe dose of ethanolic Eruca sativa leaves extract in healthy adult male rats. Twenty-five male Wister rats were divided into 5 groups: Group I (Control): received no treatment, groups 2, 3, 4, and 5 received 1, 3, 5, and 6 g/kg BW orally per day for 35 days. On the 36 day, rats were euthanized. Body weights were recorded. Serum biochemical analysis and the expression level of liver and kidney p53 and Bcl-2 were determined. Histopathology of liver and kidney, and TNF-α immunohistochemistry were examined. The ethanolic extract revealed the content of phenols, flavonoids, and fatty acids. Determination of biochemical parameters showed no significant difference in the estimated parameters between control and treated groups. While the treated groups did not show any significant changes expressions of p53 and Bcl-2 as observed by histopathological and immunohistochemical examination as compared to the control group, liver and kidney toxicity occurred for the rat groups administered 6g/kg. In conclusion, Eruca sativa is not toxic and there were no structural and functional changes in the liver and kidney when administered the doses of 1–5 g/Kg BW over a 35-day period through its potent antioxidant activity in rats and that toxicity that occurred in the 6g/kg-day group may be caused by a high concentration of glucosinolates.
Surface roughness and Streptococcus mutans adhesion on surface sealant agent coupled interim crown materials after dynamic loading by simulated chewing forces
Authors: şahin onur , Topçu Eda , Köroğlu Ayşegül , Cömert Füsun , Yılmaz Burak
Published: March 2022

Background: Surface sealant agents have been developed as an alternative to conventional polishing methods. These agents can achieve smoother surfaces in less time than conventional methods, studies on the condition of these agents against the chewing forces are lacking. The purpose of this study is to evaluate the surface roughness and the adhesion of Streptococcus mutans adhesion after chewing simulation of surface sealent coupled interim prosthetic materials.Methods: One hundred and twelve specimens were fabricated from two poly(methyl methacrylate) (Tab 2000, Dentalon Plus) and two bis-acryl (Tempofit, Protemp 4) interim crown materials and divided into 4 groups (n=7) according to applied surface treatment procedures: conventional polishing (control) and 3 surface sealant (Palaseal, Optiglaze, Biscover) coupling methods. The surface roughness values were measured with a profilometer before (Ra0) and after aging process through dynamic loading in a multifunctional chewing simulator for 10,000 cycles at 50 N load combined with integral thermocycling (between 5°C and 55°C) (Ra1). Specimens were incubated with Streptococcus mutans suspension and bacterial colonizations were evaluated.Results: Except the use of Optiglaze and BisCover LV surface sealant agents on Protemp 4 and the use of Palaseal and Biscover LV on Tempofit; surface sealant agent application significantly decreased the surface roughness compared with the conventionally polished specimens. Statistically, surface roughness after dynamic loading showed a significant increase in all groups, except Tab 2000 and Protemp 4 control groups. A positive correlation was found between surface roughness values of interim prosthodontic materials and the quantitiy of Streptococcus Mutans. Conclusions: Even though surface sealant agent application significantly decreased the surface roughness compared with the conventionally polished specimens, dynamic loading significantly increased the surface roughness of all surface sealant coupled groups. The Ra values of all test groups were higher than the plaque accumulation threshold (0.20 µm). Streptococcus mutans adhered more on rougher surfaces.
Magneto-Optical Kerr effect in surface engineered 2D hexagonal boron nitride
Authors: Mirabbaszadeh Kavoos , Torkashvand Ziba , Shayeganfar Farzaneh , Lee Changgu
Published: March 2022

Magnetism in atomically thin functional materials can be an important phenomenon for exploring two-dimensional magneto-optics. Magneto-optical experimental data have revealed significant Kerr signals in insulator thin films. Here, the magneto-optical Kerr effect of oxygen functionalized and doped hexagonal boron nitride (hBN) has been investigated by performing first-principles calculations. We calculated Kerr angle and Kerr ellipticity for functionalized hBN as an attention-drawn material. Moreover, increasing of oxygen doping percentage leads to the introduction of surface plasmon to hBN. Our findings show that the functionalized hBN can tolerate high-temperature conditions, keeping oxygen atoms bridge-bonded. These giant opto/magnetic responses of insulating 2D materials provide a platform for the potential designing of magneto-optical devices.
Impacts of Climate Change on Spatial Drought Distribution in Mediterranean Basin: Different Climate Models and Downscaling Methods
Authors: Erkol Zülküf İbrahim , Yesilyurt S. Nur , Dalkilic H. Yildirim
Published: March 2022

The impacts of climate change increasingly show themselves in many forms in our everyday lives such as heatwaves and droughts. Drought is one of the critical events today for increasing drought frequency. This study focuses on meteorological drought because it directly affects other drought types. Hence, this study focuses on how the future drought conditions will vary under climate change effects in the Mediterranean basin. In doing so, this study utilizes precipitation data of three General Circulation Models (GCMs) and three Regional Circulation Models (RCMs). The GCMs are CNRM-CM6, GFDL-CM4, and MPI-ESM1, while the RCMs are CNRM-CM5, GFDL-ESM2M, and MPI-ESM-MR. Mitigating biases of the climate models, this study utilizes four Statistical Downscaling methods (SD), linear scaling (LS), local intensity scaling (LOCI), power transformation (PT), and distribution mapping (DM). Here, the study has two purposes. First, it compares the performances of SD methods in improving climate models' representation of observed climate variables. Second, the study shows how different methods will affect spatial drought distribution in the area under SSP2 RCP4.5 and RCP8.5 scenarios. Consequently, the study uses the Standardized Precipitation Index (SPI) and Z-score Index (ZSI) to quantify future drought conditions and reaches the following results. The study reveals that mild drought conditions are prevalent in the basin for future periods, and drought indices go down to -0.55. The study also shows that different SD methods affect the results obtained by each climate model diversely. For example, while the LS method causes the most drought conditions on the results based on CNRM-CM5 and CNRM-CM6, the DM method has a similar impact on outcomes based on GFDL-CM4 and GFDL-ESM2M and causes the most drought conditions.
Partially Resolving Myocardial Fibrosis Following the mRNA COVID-19 Vaccine: An MRI Based Case Report
Authors: Imran AFM Ashik , Park Won Jun , Sood Michael R.
Published: March 2022

Introduction:Myocarditis is a disease that has varying degrees of clinical manifestations. Furthermore, its diagnosis and management can pose as a challenge to clinicians. With over 250 million people receiving the mRNA covid vaccine, there have been rare reports of myocarditis, pericarditis or other cardiovascular involvement. However, its natural course remains unclear. Case:We report a 30-year-old healthy male who was hospitalized 3 days after the second dose of the covid-19 vaccination. He had high cardiac laboratory markers (cardiac troponin I peak of 22 ng/mL, normal <0.03 ng/mL). He had a subsequent coronary angiogram and echocardiogram that were normal and was hence diagnosed with myocarditis. After week 3, his symptoms fully abated along with all of his inflammatory and cardiac markers. He had a cardiac magnetic resonance (CMR) study 8 weeks later (from the date of his vaccine dose) that showed prominent mid to epicardial lateral wall fibrosis with normal T1 and T2 mapping. A repeat CMR was performed 3 months later, which is almost 22 weeks since the vaccine administration. It showed persistent, though partially resolving fibrosis, despite full resolution of symptoms and biomarkers, demonstrating an insidious recovery. Conclusion:This case demonstrates myocarditis following the second dose of the mRNA covid-19 vaccination with evidence of myocardial fibrosis on CMR and on follow-up CMR scan nearly 5 and a ½ months from administration. Furthermore, it shows remaining evidence of myocardial fibrosis despite the normalization of symptoms and traditional screening methods such as echocardiography and the use of cardiac and inflammatory biomarkers in disease surveillance. It provides insight into its natural course and insidious recovery as well as the utility of CMR in clinical management.