bluuebunny/crossref_metadata_2025 huggingface dataset:
Immobilization of Amano AK Lipase from Pseudomonas fluorescens on Novel Silk Microfiber using Oxone®: Parameter Optimization for Enzymatic Assays and use in Esterification of Residual Palm Oil
Authors: Júnior Evaldo B.M. , Neves Fernando B. , Lopes Samuel Q. , Holanda Fabrício H. , Souza Tiago M. , Pinto Erveton P. , Oliveira Alex N. , Fonseca Luis P. , Yoshioka Sérgio A. , Ferreira Irlon M.
Published: April 2021

Background:

Biodiesel has been shown to be effectively produced by immobilized enzymatic
catalysts. The selection of support material is a prominent factor for obtaining an efficient
lipase. Silk fibroin (SF) is a natural polymer produced by glands of some arthropods, especially by
the Bombyx mor, attracting attention for immobilization of lipase.

Objective:

This paper presents a novel method to obtain silk microfibers (SMF) from Oxone® salt
in water, used as support for Amano AK lipase from Pseudomonas fluorescens in biodiesel production
from deodorization distillate of palm oil (DDPO).

Method:

The oxone® salt in the presence of Ca2+ ions acts as a mineralizing agent in the peptide
bonds present in silk fibroin, altering some of its physical and chemical properties, such as zeta
potential, crystallinity, micro-morphology, infrared spectroscopic profile, and showing formation
or absence of SF original connections.

Results:

The modified support was tested as a support alternative for the immobilization of Amano
AK lipase from Pseudomonas fluorescens. Enzyme activity values indicated that lipase immobilization
on SMF was efficient as a heterogeneous catalyst in the esterification of DDPO (deodorization
distillate palm oil).

Conclusion:

The effect of some reaction parameters, such as catalyst concentration, molar ratio,
temperature, and reaction time, was studied to optimize the conditions for maximum conversion of
DDPO (40.5%).
Synthesis and Pharmacological Activities of Oxadiazole and Pyrimidine Bearing Thiocoumarin Derivatives
Authors: Tiwari Monika R. , Patel Navin B.
Published: April 2021

Aims:

The study aims to synthesize thiocoumarin scaffolds clubbed with pyrimidine
and 1,3,4-oxadiazole ring system under microwave irradiation and describe their pharmacological
activities.

Background:

We report herein an efficient and simple Lewis acid-catalyzed procedure for the
synthesis of novel series of thiocoumarin clubbed with pyrimidine and 1,3,4-oxadiazole motifs
under microwave irradiation. The microwave-assisted technique has many advantages, such as a
higher yield, a clean and selective procedure, shorter reaction time, and simple work-up.

Objective:

The objective of the present study is to design and synthesize thiocoumarin scaffolds
clubbed with pyrimidine and 1,3,4-oxadiazole ring system by microwave-assisted heating. Our
prime focus is to highlight the synthetic approach developed for the synthesis of heterocyclic moieties
of pharmacological interest, and the prominence has also been given to distinct advantages
provided by microwave heating.

Methods:

Thiocoumarin clubbed with pyrimidine, and 1,3,4-oxadiazole motifs was synthesized
under microwave irradiation. All the synthesized molecules were evicted by IR, 1H NMR, 13C
NMR, and mass spectra. The anti-microbial activity of synthesized compounds was examined
against two Gram-negative bacteria (E. coli, P. aeruginosa), two Gram-positive bacteria (S. aureus,
S. pyogenes), and three fungi (C. albicans, A. niger, A. clavatus) using the MIC (Minimal Inhibitory
Concentration) method, anti-tubercular activity H37Rv using L. J. Slope Method and anti-
oxidant activity using DPPH and ABTS bioassay method.

Results:

The application of microwave technology for the rapid synthesis of biologically significant
thiocoumarin analogues is very promising because of its shorter reaction time and higher
yield. Some of these new derivatives showed moderate to good in-vitro anti-bacterial, anti-fungal,
and anti-tubercular activity. Compounds B4 and B7 appeared to have high radical scavenging efficacies
as 35.32 ± 0.446 and 33.97 ± 1.069 μg/mL ± SD of IC50 values in DPPH and ABTS bioassay,
respectively.

Conclusion:

Microwave-assisted synthesis provides an implicit way to discover a promising class
of molecular entities for the development of new anti-microbial and anti-oxidant agents. Oxadiazole
and pyrimidine bearing thiocoumarin derivatives showed improved anti-microbial, antitubercular,
and anti-oxidant activity.
Pemberdayaan Perempuan Melalui Pelatihan Kewirausahaan Menjahit
Authors: Ratnasari Sri , Saripah Iip , Akhyadi Ade Sadikin
Published: April 2021

Education is the right for every citizen of Indonesia so that everyone has equal rights to education. Entrepreneurial spirit must be applied to each individual where this requires that each individual has good soft skills and hard skills in order to create quality human resources. This can be achieved by empowering women. The purpose of this research is to provide a study on women's empowerment and entrepreneurship in real terms according to the results of field research. This research method uses a descriptive qualitative approach. The result of this research is that entrepreneurship is one of the efforts in community empowerment, especially for learning citizens. Entrepreneurship can create the development of the community's potential to develop optimally. Community empowerment and development provide guidance and support so that people are able to carry out their roles and duties in life.
Precarious Living: Assessing the Disaster Risk Vulnerability of Selected Informal Settlers in Dasmariñas City, Philippines
Authors: Aguilar Maria Virginia
Published: April 2021

From the perspective of disaster management, the proliferation of slums and informal settlers pose a serious problem because their economic status  inadvertently drive them to spaces unsuitable for housing. The informal settler often reside in areas prone to flooding, seismic activity and landslides exposing them to a vicious repeat cycle of destruction and loss of life. Sitio Bato, a newly-formed informal settlers’ community in Dasmarinas City, Philippines,  is a case point. Situated near a creek and without electricity and water connection (at the start of study in 2019),  the residents are seemingly susceptible to disaster hazards. Against this backdrop, this study seeks to discuss the knowledge, attitudes and practices  of the residents of Sitio Bato regarding their vulnerability to disasters and the views of selected local government officials regarding the self-assessment of the informal settlers. Through survey among household heads and key informant interviews of local leaders, the following findings were notable in the study. First, the residents were knowledgeable of preventive mechanisms of floods, such as the important function of trees and proper waste disposal to exclude waterways. The residents’ neighborhood organization is recognized by the barangay officials, and hence, their attendance to seminars/training on disaster management might have helped. Second,  in terms of attitude, it appears that it is innate for the informal settlers to care for their neighbors, and thus, it is part of their daily activity to check on each other’s family. The lack of electricity encourage them to stay outdoors and talk to each other, strengthening their bond. Third, in terms of practice, disposal of trash to the creek is not done, and hence, water from the creek flows without obstruction. Recyclable trash coming from communities in the upper part of the creek are collected by a few Sitio Bato residents. Overall, residents do not perceive that their living in Sitio Bato as precarious or hazardous. Local officials generally perceive the city’s informal settlers as “privileged” because the services offered by the city government is received by everyone, regardless of the legality of their residence.
The adaptation of scientific reasoning of prospective teachers for primary education in the perspective of civic science
Authors: Hidayah Yayuk , Dewi Dinie Anggraeni , Trihastuti Meiwatizal
Published: April 2021

This article aims to determine the adaptation of prospective elementary school teachers' scientific reasoning from a civic science perspective through seminar courses on elementary schools' educational problems. The issue of distance learning during the Corona Virus Disease (Covid) 19 pandemic in Indonesia has led to various highlights and analyzes. The learning scheme's quality and learning scheme are among the most popular questions in this learning scheme. This research uses a case study with a qualitative approach with data collection using interviews, observation, documentation, and literature studies. The results showed that the adaptation of the scientific reasoning of prospective elementary school teachers in a civic science perspective through the Seminar on Educational Problems in Primary Schools has several characteristics,  that is: 1) educational problems in primary schools captured by dominant students in technological literacy, 2) study of educational problems in schools fundamental relates to the realization of smart and good citizens that reflected in attitudes and behavior in the Covid-19 pandemic situation, and 3) there is character building in the adaptation of scientific reasoning in the civic science perspective. Therefore, the research expects to have implications in developing civic education knowledge, especially in elementary school, which aims to strengthen the study of civic education.
The relationship between education level, retirement status, and civic engagement among older adults in Indonesia
Authors: Winata I Komang
Published: April 2021

The Indonesian population is aging very rapidly and as the number of old people increases, the number of retirees increases as well. Many scholars have argued the benefits of civic engagement in old age, but there is lack of empirical evidence of the factors associated with civic engagement in Indonesia. The aim of this study was to investigate the association between education levels, retirement status, and civic engagement among older adults in Indonesia. The study used data from the fifth wave of the Indonesia Family and Life Survey which was held in late 2014 and early 2015. The study included participants aged 56 years and older, the mandatory age for retirement in 2014 in Indonesia.  Multiple regression was modelled for data analysis. The main results revealed that those who completed junior and senior high school and high education exhibited more civic engagement than those who completed only primary education. Moreover, the study found that those who were retired were less engaged in civic activities than those still in labor force. These relationships held true even after controlling for gender, age, marital status, personality traits, religiosity, and self-rated health variables. To strengthen democracy and growth, education needs to be re-emphasized and there is need for further investigation concerning retirement and civic engagement in Indonesia.
Project citizen model to develop student's pro-social awareness
Authors: Romlah Oom Yomi , Syobar Khaerul
Published: April 2021

Students’ learning activities cannot be separated from various factors. The purpose of this study was to determine how project citizen model developed students' pro-social awareness. This study was motivated by diminishing pro- social awareness among students. This study was conducted qualitatively by using case study. The results showed that through project citizen model, students' pro-social awareness could develop. Besides, project citizen model could help students think critically about social reality. This study recommended to maximize the use of project citizen as a learning model that could develop various potencies of students.
Building religious, honesty, discipline and student curiosity characters in online HOTS-based citizenship education learning
Authors: Chotimah Umi , Kurnisar Kurnisar , Ermanovida Ermanovida , Juainah Norma
Published: April 2021

This article aims to describe the efforts to build religious, honesty, discipline, and student ‘s curiosity characters through HOTS-based online Civics learning. The implementation uses a qualitative approach with the case study method, which is implemented in the Indralaya class Civics learning process. Data were collected through observation, interviews, and documentation, then analyzed using three stages from Miles Huberman, namely data reduction, data display and data verification/conclusion. The results show that building religious , honesty, discipline, and student curiosity characters in HOTS-based Civics learning can be pursued even though the implementation is online learning system. This character development is carried out through various activities, starting from planning, implementing student-oriented learning, and comprehensive assessment. However, this does not mean that apart from the four characters, there is no need to develop other characters. It means that other characters are still built but in line with each learning outcomes and each meeting's subject matter.
Synthesis, characterization, and performance of oligothiophene cyanoacrylic acid derivatives for solar cell applications
Authors:   Department of Physics, Faculty of Science, Mu'tah University, Mu'tah, Jordan, et al. Al-Dmour
Published: April 2021

New dye sensitizers based on an oligothiophene cyanoacrylic acid derivative were synthesized and characterized for solar cell applications. The structures of the new dyes prepared as sensitizers based on oligothiophenes, namely5,5''-di-2-cyanoacrylic acid [2,2':5',2''-terthiophene] (dye1), [2,2':5',2''-terthiophene]-5-cyanoacrylic acid(dye2), and [2,2':5',2'':5'',2'''-quaterthiophene]-5-cyanoacrylic acid(dye3) were confirmed by elemental analysis, mass spectrometry, and 1H-NMR spectral data. The P3HT/dye2/nc-TiO2 solar cell produced the highest efficiency of 0.05% with an open circuit voltage of 0.65V compared to dyes 1 and 3 solar cells. That may have been attributed to the dyes’ molecular structure, which had different chain lengths and numbers of groups of cyanoacrylic connected to the dyes’ thiophene moiety The dark current suppressed in the P3HT/dye2/nc-TiO2 solar cells indicated the formation of the charge blocking layer, which produced an enhanced open-circuit voltage accompanied by a high onset voltage.
Identificación de Struthiopterolichus sp. (Astigmata: Pterolichidae) en avestruces (Struthio camelus camelus) de Cauca, Colombia
Authors: Castro-Castro Fernando Favian , García-Agudelo Angie Daniela , Muñoz Luis Miguel , Cortes-Vecino Jesús Alfredo , González-Jiménez Indrid Marcela , Robayo-Sánchez Laura Natalia , Rivera-Calderón Luis Gabriel
Published: April 2021

Objetivo. Identificar ectoparásitos en las plumas primarias de avestruces adultas alojadas en un criadero del Departamento del Cauca Colombia. Materiales y métodos. Un total de 15 aves adultas (mayores de 7 años), con un peso promedio de 120 kg (10 hembras y 5 machos) fueron seleccionadas para el estudio. De cada ejemplar fueron extraídas tres plumas primarias del ala, siendo depositadas en bolsas plásticas para ser enviadas al Laboratorio de ciencias básicas de la Universidad Antonio Nariño. Una contramuestra de ácaros fijados en alcohol al 70% fue enviada a la Universidad Nacional, posteriormente, los parásitos se montaron en láminas examinadas al microscopio. Este estudio fue de tipo descriptivo y a conveniencia. Resultados. Las plumas poseían barbas desorganizadas y en su raquis un polvo de color café, al analizarlas microscópicamente, se obtuvo aproximadamente 1000 especímenes de un ácaro de pluma por muestra, del orden Astigmata, familia Pterolichidae y género Struthiopterolichus sp., lográndose diferenciar hembras, machos, ninfas y larvas. Este es el primer reporte del ácaro de Struthiopterolichus sp. en avestruces de Colombia. Conclusiones. En los avestruces inspeccionados se colectaron plumas que contenían el ácaro Struthiopterolichus sp. La evidencia de este ácaro puede generar alertas de control y vigilancia sanitaria al interior del criadero.
Postsecondary Student Engagement With a Mental Health App and Online Platform (Thought Spot): Qualitative Study Assessing Factors Related to User Experience (Preprint)
Authors: Wong Howard W , Lo Brian , Shi Jenny , Hollenberg Elisa , Abi-Jaoude Alexxa , Johnson Andrew , Chaim Gloria , Cleverley Kristin , Henderson Joanna , Levinson Andrea , Robb Janine , Voineskos Aristotle , Wiljer David
Published: April 2021

BACKGROUND

There is growing interest in using mobile apps and online tools to support postsecondary student mental health, but most of these solutions have suboptimal user engagement in real-world settings. Poor engagement can limit long-term effectiveness and usefulness of these tools. Previous literature has proposed several theories that link factors such as low usability and poor user-centered design to app disengagement. However, few studies provide direct evidence showing what factors contribute to suboptimal user engagement in the context of mobile mental health apps for postsecondary students.

OBJECTIVE

This study focuses on understanding postsecondary students’ attitudes and behaviors when using Thought Spot, a co-designed mental health app and online platform, to understand factors related to engagement and user experience.

METHODS

Students who were given access to Thought Spot for 6 months during a randomized trial of the intervention were invited to participate in one-on-one semistructured interviews. The interviews explored participants’ overall experiences and perceptions of the app, along with factors that affected their usage of various features. All interviews were recorded, and template analysis was used to analyze transcripts.

RESULTS

User satisfaction was mixed among users of Thought Spot. The degree of engagement with the app appeared to be affected by factors that can be grouped 5 themes: (1) Students valued detailed, inclusive, and relevant content; (2) Technical glitches and a lack of integration with other apps affected overall user experience and satisfaction with the app; (3) Using the app to support peers or family can increase engagement; (4) Crowdsourced information from peers about mental health resources drove user engagement, but was difficult to obtain; and (5) Users often turned to the app when they had an immediate need for mental health information, rather than using it to track mental health information over time.

CONCLUSIONS

Content, user experience, user-centeredness, and peer support are important determinants of user engagement with mobile mental health apps among postsecondary students. In this study, participants disengaged when the app did not meet their expectations on these determinants. Future studies on user engagement should further explore the effectiveness of different features and the relative importance of various criteria for high-quality apps. Doing so may inform the creation of interventions that best engage students and align with their mental health needs.

CLINICALTRIAL

ClinicalTrials.gov NCT03412461; https://clinicaltrials.gov/ct2/show/NCT03412461

INTERNATIONAL REGISTERED REPORT

RR2-10.2196/resprot.6446
A Semiautomated Chart Review for Assessing the Development of Radiation Pneumonitis Using Natural Language Processing: Diagnostic Accuracy and Feasibility Study (Preprint)
Authors: McKenzie Jordan , Rajapakshe Rasika , Shen Hua , Rajapakshe Shan , Lin Angela
Published: April 2021

BACKGROUND

Health research frequently requires manual chart reviews to identify patients in a study-specific cohort and examine their clinical outcomes. Manual chart review is a labor-intensive process that requires significant time investment for clinical researchers.

OBJECTIVE

This study aims to evaluate the feasibility and accuracy of an assisted chart review program, using an in-house rule-based text-extraction program written in Python, to identify patients who developed radiation pneumonitis (RP) after receiving curative radiotherapy.

METHODS

A retrospective manual chart review was completed for patients who received curative radiotherapy for stage 2-3 lung cancer from January 1, 2013 to December 31, 2015, at British Columbia Cancer, Kelowna Centre. In the manual chart review, RP diagnosis and grading were recorded using the Common Terminology Criteria for Adverse Events version 5.0. From the charts of 50 sample patients, a total of 1413 clinical documents were obtained for review from the electronic medical record system. The text-extraction program was built using the Natural Language Toolkit Python platform (and regular expressions, also known as RegEx). Python version 3.7.2 was used to run the text-extraction program. The output of the text-extraction program was a list of the full sentences containing the key terms, document IDs, and dates from which these sentences were extracted. The results from the manual review were used as the gold standard in this study, with which the results of the text-extraction program were compared.

RESULTS

Fifty percent (25/50) of the sample patients developed grade ≥1 RP; the natural language processing program was able to ascertain 92% (23/25) of these patients (sensitivity 0.92, 95% CI 0.74-0.99; specificity 0.36, 95% CI 0.18-0.57). Furthermore, the text-extraction program was able to correctly identify all 9 patients with grade ≥2 RP, which are patients with clinically significant symptoms (sensitivity 1.0, 95% CI 0.66-1.0; specificity 0.27, 95% CI 0.14-0.43). The program was useful for distinguishing patients with RP from those without RP. The text-extraction program in this study avoided unnecessary manual review of 22% (11/50) of the sample patients, as these patients were identified as grade 0 RP and would not require further manual review in subsequent studies.

CONCLUSIONS

This feasibility study showed that the text-extraction program was able to assist with the identification of patients who developed RP after curative radiotherapy. The program streamlines the manual chart review further by identifying the key sentences of interest. This work has the potential to improve future clinical research, as the text-extraction program shows promise in performing chart review in a more time-efficient manner, compared with the traditional labor-intensive manual chart review.
COVID-19 Data Utilization in North Carolina: Qualitative Analysis of Stakeholder Experiences (Preprint)
Authors: Patterson Jenny Rees , Shaw Donna , Thomas Sharita R , Hayes Julie A , Daley Christopher R , Knight Stefania , Aikat Jay , Mieczkowska Joanna O , Ahalt Stanley C , Krishnamurthy Ashok K
Published: April 2021

BACKGROUND

As the world faced the pandemic caused by the novel coronavirus disease 2019 (COVID-19), medical professionals, technologists, community leaders, and policy makers sought to understand how best to leverage data for public health surveillance and community education. With this complex public health problem, North Carolinians relied on data from state, federal, and global health organizations to increase their understanding of the pandemic and guide decision-making.

OBJECTIVE

We aimed to describe the role that stakeholders involved in COVID-19–related data played in managing the pandemic in North Carolina. The study investigated the processes used by organizations throughout the state in using, collecting, and reporting COVID-19 data.

METHODS

We used an exploratory qualitative study design to investigate North Carolina’s COVID-19 data collection efforts. To better understand these processes, key informant interviews were conducted with employees from organizations that collected COVID-19 data across the state. We developed an interview guide, and open-ended semistructured interviews were conducted during the period from June through November 2020. Interviews lasted between 30 and 45 minutes and were conducted by data scientists by videoconference. Data were subsequently analyzed using qualitative data analysis software.

RESULTS

Results indicated that electronic health records were primary sources of COVID-19 data. Often, data were also used to create dashboards to inform the public or other health professionals, to aid in decision-making, or for reporting purposes. Cross-sector collaboration was cited as a major success. Consistency among metrics and data definitions, data collection processes, and contact tracing were cited as challenges.

CONCLUSIONS

Findings suggest that, during future outbreaks, organizations across regions could benefit from data centralization and data governance. Data should be publicly accessible and in a user-friendly format. Additionally, established cross-sector collaboration networks are demonstrably beneficial for public health professionals across the state as these established relationships facilitate a rapid response to evolving public health challenges.
HYMENOPTERA TOXINS: BIOLOGICAL ACTIVITY, PHARMACEUTICAL AND THERAPEUTIC USES
Authors: SHARMA SIMRAN , UPADHYAY RAVI KANT
Published: April 2021

The present review article explains the salient features of hornet venom toxins, their physiological, biological and pharmacological effect on animals and man. Hornets sting very fast and inflict venom, which is more dangerous than those of bees. Hornet venom contains both proteinaceous and non-proteinaceous peptides i.e. scapin, adolapin, mellitin, mastoparans and enzymes, mainly phospholipase and hyaluronidase, which show multiple biological effects i.e. cytolytic, hemotoxic, neuro-inhibitor, anticancer, anti-parasitic, immune hypersensitive, inflammatory, antimicrobial and anti-insect activities. Hornet stings are more painful to humans than typical wasp stings because hornet venom contains a large amount (5%) of acetylcholine. Hornet toxin components interact with receptors, ion channels and gated channels and affect the permeability functions of cells. Heavy envenomation shows quick pathophysiological lethal effects in man and pet. This article emphasizes the use of various hornet venom components for the production of disease-modifying anti-rheumatic and analgesic, anticancer drugs and insecticides. Hornet venom allergens could be used to prepare the rational design of component-resolved diagnosis of allergy and venom immunotherapy of inflicting patients.
ANTIOXIDANT, PTP 1B INHIBITION AND Α-AMYLASE INHIBITION PROPERTY AND GC-MS ANALYSIS OF METHANOLIC LEAVES EXTRACT OF ACHYRANTHES ASPERA AND CATHARANTHUS ROSEUS OF NEPAL
Authors: YASHODA KARKI , DEEGENDRA KHADKA , BIMALA SUBBA
Published: April 2021

Objective: The present study was designed to study phytochemicals and biological activities of the methanolic extracts of two traditional medicine plants Achyranthes aspera and Catharanthus roseus of Nepalese origin.

Methods: Plant extracts were prepared by cold percolation method. Antioxidant activity, brine shrimp lethality assay, and analysis of phytochemical constituents were carried out using standard methods. The dinitro salicylic acid (DNS) method was used to study the inhibition effect of extracts on α-amylase enzyme. Furthermore, PTP 1B inhibitory activity was evaluated using p-nitrophenyl phosphate (p-NPP) as substrate.

Results: Phytochemical analysis showed the presence of phytochemicals like alkaloids, flavonoids, glycosides, reducing sugars, etc. in both plants. Brine shrimp lethality assay suggested the presence of pharmacologically active compounds. Total phenolic content and total flavonoid content of C. roseus were found to be higher with 73.21 mg GAE/g and 33.15 mg Q/g respectively than that of A. aspera, which was found to be 57.09 mg GAE/g and 28.96 mg Q/g respectively. Similarly, the α-amylase inhibition of A. aspera and C. roseus was found to be 97.60±1.11 µg/ml and 94.05±1.18 µg/ml comparative with IC50 68.13±0.46 µg/ml of standard acarbose. Protein tyrosine phosphatase 1B (PTP1B) inhibition showed IC50 for A. aspera and C. roseus to be 48.72±0.46 and 50.21±1.03 µg/ml, respectively. Qualitative GC-MS analysis of both plant hexane fractions showed acid and ester type of phytoconstituents.

Conclusion: These results suggested that both plants i. e A. aspera and C. roseus, Nepal origin showed biological activity by targeting multiple drug targets which justifies their traditional uses.
PRE-PHYSICAL REALITY AND RELATIONAL PHYSICS
Authors: Panov V. F
Published: April 2021

The concept of substantive-relational “paradigm relativity-complementarity” is being developed. «Pre-physical reality» is introduced as monistic Supercategory. It is justified that it is reasonable to consider discrete complex relations and p -adic complex relations in relational physics. It is pointed out that it is important to find a way to control gravity through electromagnetic interaction. The features of quantum theory in the relational paradigm have been considered.
DOES PHILOSOPHY REALLY IMPORTANT TO PHYSICS TO LEAVE IT FOR THE REQUEST OF PHILOSOPHES?
Authors: Terekhovich V. E
Published: April 2021

In this article, I analyze the arguments against the importance of the ontological and epistemological issues of modern physics. The connection between physics and philosophy is examined on the basis of several concepts of the connection between philosophy and science. I conclude that only physicists can effectively solve the philosophical issues of their field of science. Subsequently, it can accelerate the revolutionary transformations in the physical picture of the world.
MODERN PHYSICS AND THE TEACHINGS OF ANTIQUITY (DID ANCIENT PHILOSOPHERS DISCOVER THE SAME WORLD, WHICH CREATES THEORETICAL PHYSICS?)
Authors: Kazaryan V. P
Published: April 2021

The article raises the question - how the scientific world of quantum physics and the universe of philosophers of antiquity relate: or they coincide; or these are different-disproportionate worlds; or there is continuity between them. Attention is drawn to the historical nature of knowledge. A distinction between philosophical and scientific ontologies is introduced; this makes it possible to show that quantum physics and ancient philosophy unfold their knowledge in various ontological concepts, so it is baseless try to compare them.
K.F. VON WEIZSÄCKER’S RELATIONAL PROGRAMME TO BUILD PHYSICS
Authors: Sevalnikov A. Yu , Rodina A. V
Published: April 2021

This paper is devoted to the key ideas of K. F. von Weizsäcker. His book “Aufbau der Physik”, which is dedicated to building a unified physical theory, is in the focus. Confirming that quantum mechanics is a universal physical theory, Weizsäcker is looking for ways to construct it. Based on the logic of temporary statements, introducing the concept of the Uralternative, Weizsäcker comes to the construction of quantum theory. He shows that on its basis the theory of relativity can be obtained, the structure of space with a relational character can be deduced.
MACH PRINCIPLE AND PRINCIPLE OF RELATIVITY
Authors: Nikitin A. P
Published: April 2021

The article considers the “many-faced” Mach principle and the principle of relativity, which are organically related due to the unity of nature, and provides a brief historical overview of the primary sources of these principles. Ernst Mach formulated his principle by criticizing Newtonian mechanics in his book [1] in 1896. A. Einstein, first using the term “Mach principle” in 1918, wrote that the general theory of relativity is based on three main points, one of which was the Mach principle [2. P. 613]. Currently, Mach principle is used as one of the three main provisions of the relational theory of Yu.S. Vladimirov [3]. The article also describes A. Einstein’s thought experiment from the article “Is there a gravitational effect similar to electrodynamic induction?” [2. P. 223] and about numerous experiments based on various physical principles, with the aim of checking Mach principle.
MACH PRINCIPLE AND SPACE-TIME METRIC
Authors: Vladimirov Yu. S
Published: April 2021

There are five arguments in favor of the statement that the metric (the concepts of lengths, intervals, time intervals) is determined by the influences of the entire surrounding world on the properties of the observed objects: 1) logical consequences of recognizing the relational nature of classical space-time and describing interactions based on the concept of long-range, 2) sequential relational interpretation of the Feynman - Wheeler absorber theory, 3) comparison of electromagnetic radiation densities and “scattering” galaxies, 4) mathematicians changing the axiom of Archimedes, 5) keeping the ideas of “metaphysics of light”.
HYPERBOLIC FIELDS. SEARCH EXPERIMENTS WITH A VACUUM DIODE
Authors: Pavlov D. G , Kokarev S. S , Gorlova Yu. V , Lapshin A. V , Panchelyuga M. S , Panchelyuga V. A
Published: April 2021

The article describes experiments carried out on the high-current pulsed electron accelerator Terek-2. The experiments, in their main features, reproduce the results obtained earlier in the Proton-21 laboratory. The incentive to carry out the experimental studies described in the article was an attempt to experimentally confirm the idea of a “hyperbolic lens” described in [1].
SUTHERLAND-EINSTEIN HYPOTHESIS ON THE ORIGIN OF MAGNETIC FIELDS IN ASTROPHYSICAL OBJECTS
Authors: Babenko I. A
Published: April 2021

The article discusses the theoretical and experimental foundations of the hypothesis on the origin the magnetic field's the Earth's and other astrophysical objects, put forward at the beginning of the twentieth century by Sutherland and Einstein. According to this hypothesis, the different of the electric charg of the electron and proton and the rotation of the Earth (astronomical), leads to the appearance of a magnetic field. Experiments under terrestrial conditions aimed at determining the difference between the electric charges of an electron and a proton are discussed.
INFLUENCE OF P-RADIATION ON PHYSICAL, CHEMICAL AND BIOLOGICAL SYSTEMS. RESULTS OF SOME SEARCH EXPERIMENTS
Authors: Panchelyuga V. A , Diatroptov M. E , Kolokolov D. V
Published: April 2021

The paper presents search experiments of the dependence of the parameters of physical (alpha decay of the Pu-239 isotope), chemical (fluctuations in a water cell) and biological (male Wistar rats) systems on the direction of rotation of the Poynting vector. It was found that in the case of clockwise rotation of the Poynting vector, an increase in the rate of radioactive decay by about 2 % is observed in comparison with the case without exposure. There is also an effect on the parameters of fluctuations in the water cell. When rotated counterclockwise, no such change is observed. In the case of biological systems, reactions that depend on the direction of rotation of the Poynting vector are also observed.
SOME EFFECTS OF THE SVM GENERATOR ON MELTS OF METALS AND POLYMER MATERIALS
Authors: Panov V. F , Boyarshinov A. E , Klyuev A. V , Kurapov S. A
Published: April 2021

The paper presents the latest results of the effect of SVM generators on melts of metals and polymeric materials, as well as the effect on metals during heat treatment. Shown is a block diagram of an installation for SVM material processing. Made an attempt to theoretically substantiate the use of SVM generators in metallurgy based on relational physics, quantum theory, and real relativity.
State of Rosa acicularis L. coenopopulations in forest park zone of Ekaterinburg
Authors: Tishkina Elena Aleksandrovna
Published: April 2021

The experiments revealed that the studied fragments of Rosa acicularis L. coenopopulation were normal and full-fledged with single-vertex ontogenetic spectra. They are able to form self-sustaining habitats for several generations and spread over a significant territory. Three periods and six ontogenetic states were distinguished in the ontogenesis of Rosa acicularis L. The age structure had three types of spectrum - left-sided, centered, and right-sided. The difference in the ontogenetic structure depends on influence of anthropogenic factor, ecological and coenotic conditions of rose habitats, and variations in climatic conditions. When analyzing the parameters of coenopopulations, we found that the best conditions for existence of Rosa acicularis L. were in the berry pine forest (FCP5) in the park named after Foresters of Russia and reed grass pine forest (FCP1) in Uktus forest park, where the habitats were characterized by high morphological indicators, numbers and high values of the pregenerative fraction.
Media Regionalism as a Historical Feature of Quebec Mass Media
Authors: Ovcharenko Elena F.
Published: April 2021

The current issue of information access for different nations within one state is examined. The media of Quebec, the only francophone province of Canada, give us a clear example. However, Russian scholars almost disregard this domain. Therefore, the research is based on the Canadian works (M. Brunet, A. Beaulieu and J. Hamelin, W.H. Kesterton) in French and in English. The Royal Commission on Newspapers Report (1981), which described two separate media systems (French media and English media), was used as well. The focus is on the Franco-Canadian national problem and its influence on Quebec media historic evolution. This process moves from bilingual editions (two first newspapers were published in French and in English simultaneously) to modern monolingual media system. Through comparative analysis, the relationship between media bilingualism and media monolingualism in Quebec of 18-21st centuries is examined. Quebecs modern information politics can be defined as media regionalism (French language and specific Quebec content). Media regionalisms object is to resist federal doctrine one country - one nation with two languages, the base of Official Language Act (1969). As a result, the absence of traditional federal official media bilingualism in Quebec, which tries to save its national heritage by media regionalism, was discovered.
A Prototype of Vadim Roshchin in the “White” Version of Alexey N. Tolstoy's Trilogy The Road to Calvary
Authors: Sokolov Boris V.
Published: April 2021

The article is devoted to the reconstruction of the idea of the white version of the second volume of A.N. Tolstoy's trilogy The Road to Calvary , created by the writer in the emigration in 1921-1923. This idea was fundamentally different from the one embodied by A.N. Tolstoy after his return to the USSR. Materials published in 1918 in the Rostov magazine Donskaya Volna ( Don Wave ) are used for the reconstruction. Those materials help to identify Colonel V.K. Manakin as a supposed prototype of one of the main characters, Vadim Roshchin, in the final chapters of the first volume of the trilogy and in the first chapters of the second volume of the white version. The prototype makes it feasible to reconstruct the possible idea of the second volume of the white version of The Road to Calvary . A.N. Tolstoy's notebooks are also used for the reconstruction. The reconstruction of A.N. Tolstoys plan turned out to be more logically consistent compared to the only existing Soviet version of the second and third volumes of the trilogy The Road to Calvary. Both Roshchin and Telegin, in the emigrant version of the first volume of the trilogy act as ideologists of the White Movement, find themselves in the White Armies of Southern Russia, and then in exile. The study shows that the transition of the main characters to the Red Movement in the Soviet version of The Road to Calvary is artistically unconvincing, since it does not correspond to the original plan of A.N. Tolstoy, embodied in the emigrant version of Sisters .
The Autobiography in Paul Claudel’s MaConversion
Authors: Bannikov Konstantin V.
Published: April 2021

The article deals with the autobiography of Paul Claudel in his essay Ma Conversion written in 1913 at the request of readers. The readers believe that his biography no longer belongs to him, so the experience of his conversion should be of common property. It reveals his confessional retrospective traits and self-awareness in biographical literary works. Different types of confession, features of preaching, self-expression and autobiography are interwoven in the essay. The language of the essay is poetic and polysemantic. Distance is manifested in many ways in Claudels works, from the explicit biographical author - moi, Paul to the literary author - le pote. The writer begins in a confessional, indecisive manner, but as he becomes more professional, he resorts to the biographical author less willingly, more often remaining on the sidelines as a literary author. There is less open reflection in the collection of works Conversations (1926-1937), so the poet discusses reality, but he does not describe his feelings and actions as he did when he was younger. Claudel's autobiography combines the sacred and the secular, while the intimate and the public act as a preparatory stage to a multi-volume exegetic novel.
The Construction of Insider - Outsider in Anglophone Writings from Northeast India
Authors: Biswas Debajyoti , Das Rupanjit
Published: April 2021

The works of three writers from northeast India, Temsula Aos These Hills Called Home , Mamang Dais Stupid Cupid and Anjum Hasans Lunatic in my Head that cover the problem of identity in relation to the insider - outsider politics in the region are examined. The northeast India is in many ways a miniature India because it houses people from various ethnicity and linguistic groups. However, much of the immigration took place after the East India Company annexed the northeast region starting from 1826. The extraction of the resources and subjugation of the people in this region by the colonisers and later by successive Indian governments has left an indelible mark of cultural imperialism triggering social haemorrhage. This changing position of the insider - outsider is not only a part of the political discourse but also the literature that is produced in this region. The analysis of the writings of Temsula Ao, Mamang Dai, and Anjum Hasan allows to look at the problem from two perspectives: the indigenous population experiencing anxiety and leading various violent campaigns to expel so-called outsiders, and the northeasterners facing similar racial prejudices when visiting mainland India and being subjected to derogatory racial slurs.
TV Show Dramaturgy as an Analogue of the Audiovisual Syntax
Authors: Kemarskaya Irina N.
Published: April 2021

The dramaturgy of a television work as structure-forming for the format basis of a television periodical is examined. The purpose of the study is to explain the fundamental features of a TV program as an integral artistic phenomenon, embodied in many variations based on a single format model. The task is to clarify the problem of the effective functioning of syntactic rules in the absence of basic linguistic units, which is characteristic of the audiovisual language of screen shows, that has been actualized by domestic and Western media researchers. A general thesis is put forward about the polymodality of an audiovisual work as a single text, the unfolding of which occurs according to pre-established schemes that regulate the effect of individual elements on the viewer's perception. The dramatic approach is considered in the discourse of the global iconic turn from the verbal culture to the visual culture, there are multi-branch attempts to identify possible basic units of the new combinatorial sign system. Syntactic constructions, defined as a chain of episodes, show signs of fragmentation, mosaicism, intertextuality, and other criteria of postmodern aesthetics. The dualism of screen attractions as aggressively influencing instruments and verbal narrative, their mutual influence and dramatic significance are emphasized. The concepts of syntactic uniformity, the constancy of the syntactic structure chosen for a given format, without the possibility of breaking it in variations of editions are considered.
Scientific and Methodological Support for Teachers in the Context of Gamification in Mathematics Study in the Russian System of Additional Education
Authors: Dvoryatkina Svetlana N. , Shcherbatykh Sergey V. , Lopukhin Arseny M.
Published: April 2021

The relevance of this study is due to the practical significance of the issues of using game mechanisms in the process of teaching mathematics, the lack of research into the issues of symbiosis of game and didactic technologies in mastering complex mathematical knowledge, the need to search for effective technologies to establish how they affect the development of students and the formation of a modern style of thinking. The analysis of global trends and practices of introducing elements of gamification into the education system has shown that the mastering of complex knowledge and patterns of mathematical activity, the solution of problem areas of mathematics at different levels of learning and complexity is carried out by a complex of mathematical and information methods without the integration of game elements. It has been substantiated that gaming technologies in combination with the informatization of mathematical activity give a powerful motivational charge to the study of mathematics, actualize the processes of self-organization of cognitive activity, and contribute to the development of a probabilistic style of thinking. The purpose of the study is to provide a theoretical substantiation and effective methodological support for the process of professional development of mathematics teachers in the context of gamification in mathematics study with the effect of developing a probabilistic style of thinking. The authors have developed an arrangement mechanism and determined the content of scientific and methodological support for teachers working in the constituent entities of the Russian Federation to provide additional educational services in the context of gamification in education. The developed materials, in particular, include evaluative case tests for identifying competence deficiencies in teachers, which ensure the formation of a probabilistic style of thinking based on gamification processes by managing the information saturation of the motivational field of learning. In addition, the authors proposed an additional professional education program for teachers, Mathematics in Gaming Activities (Business, Didactic and Intellectual Games) , and developed new forms of certification and assessment materials (gamification-based didactic solutions and effective practices). Using the concept of gamification, it was possible to demonstrate the activation of cognitive and motivational structures, in particular, the effective development of a probabilistic style of thinking in the process of mastering complex mathematical knowledge through its adaptation to school mathematics. The results of the study allow making it possible to bring the process of teaching students and developing their personalities to a modern qualitative level using current achievements in the field of digitalized education.