bluuebunny/crossref_metadata_2025 huggingface dataset:
A homoeopathic drug proving of Gymnura natalensis with a subsequent comparison to existing homoeopathic remedies derived from sea animals
Authors:   , Naidoo Vanishree
Published: May 2022

The purpose of this study was to determine the effects of Gymnura natalensis in the thirtieth centesimal potency on healthy volunteers and to record the signs and symptoms produced by the volunteers during the study. These signs and symptoms determined the therapeutic indications of this remedy for its prescription according to the homoeopathic Law of Similars. A further aim of this study is a proposed group analysis of a natural family of biologically unrelated sea animal remedies (Mangialavori, 2002) with the aim of highlighting themes, similarities and differences within the group.
Factores asociados en la transmisión de la enfermedad de Hansen en Colombia: una perspectiva epidemiológica
Authors: Serna Trejos Juan Santiago , Martinez Parada Isabella , Prado Molina Diego Gerardo
Published: May 2022

Hemos leído con gran interés y aprecio su artículo titulado “Afectación familiar de la enfermedad de Hansen en Costa Rica”1  bajo la autoria de Rivera-Chavarria y Cols , puesto que supone un artículo que depara pautas de caracterización poblacional sumamente relevantes para la salud pública , más específicamente tratándose de la enfermedad de Hansen (EH), que supone una enfermedad infectocontagiosa desatendida en Colombia.
Activación inmune por productos finales de glicación avanzada
Authors: Centeno-Ureña Yadel , Ulloa-Morales Alejandro
Published: May 2022

Con el objetivo de revisar los avances recientes en la biología de los productos de glicación avanzada y su papel en diversas patologías de alta relevancia en salud pública, se realizó una búsqueda dirigida de la bibliografía entre los años 2000 y 2021 en la base de datos PubMed (NCBI) y se usaron como palabras clave “advanced glycation end products”. Se ha demostrado que el receptor de productos de glicación avanzada induce una activación sostenida del factor de transcripción proinflamatorio NF-kB y suprime una serie de funciones autorreguladoras endógenas. Este efecto influye negativamente en una gran variedad de patologías como diabetes, autoinmunidad, neurodegeneración y enfermedades infecciosas. La acumulación tisular de productos de glicación avanzada está relacionada con procesos de inflamación crónica y disfunción celular, y constituye un blanco prometedor para el diseño de tratamientos enfocados en esta vía de señalización. Actualmente se realizan múltiples ensayos clínicos para determinar su utilidad como marcador de lesiones pulmonares en COVID-19.
REAL EFFECTIVE EXCHANGE RATE AND IMPORT OF GOODS AND SERVICES LINKAGE IN NIGERIA: AN IMPACT ANALYSIS
Authors: Eje Grace Chinyere , Ugwu Okereke J.
Published: May 2022

This paper assessed the influence of real effective exchange rate on import of goods and services in Nigeria over the period, 1986-2020. The Error correction model estimation was applied in estimating the multiple regression model. The findings showed that the real effective exchange rate is negative and statistically significant effect on the exports of goods and services in Nigeria. Expectedly, the convergence coefficient or error correction term (ECT) is negatively signed and significant, which suggests that last-period’s deviation from a long-run equilibrium influences its short-run dynamics as is being corrected at a speed revealed by the parameter estimate. Thus, the speed of adjustment (or error correction term) shows that deviation from equilibrium relationship is corrected at the speed of 56% on annual basis. We recommend that we recommend that if the Nigeria wants to focus on import, the currencies should be devalued/depreciated because they are relatively elastic to changes in real exchange rate.
 Keywords: Exchange Rate, Error Correction Model, Imports, Goods, Nigeria.
NMR analysis: potential and challenges as a homeopathic basic research tool
Authors: Holandino Carla , Beier Daniela Wendhausen , Fragoso Míriam , Bastos Cintia Sias Coube , Campos Vânia Emerich Bucco , Oliveira Adriana Passos , Santos Júlia Neves , Silva Lucas Henrique , Valente Ana Paula Canedo
Published: May 2022

Background: Homeopathic ultra-diluted solutions surpass the threshold of matter dispersion and, consequently, their chemical constitution is similar to inert solvent. Nevertheless, randomized clinical trials have shown that the clinical effects of these homeopathic medicines are superior to placebo1. Nuclear magnetic resonance (NMR) is one of the most promising techniques to detect physicochemical alterations induced by homeopathic procedures2,3. Aims: To investigate T2 NMR relaxation times of Zincum metallicum and lactose dynamized samples. Methodology: Zincum metallicum samples were ground until 6dH using lactose as an excipient. Subsequently, these samples were dynamized with ultrapure water to produce 8dH, 9dH, 10dH, and 11dH. Lactose dynamized samples (6dH-11dH) were used as control. Aliquots of 540µl of each sample were diluted with 60µl of deuterated water (D2O) in 5mm tubes. The analyses were carried out in Bruker Ascend TM 500MHZ spectrometer at 288 K. Results and discussion: The Zincum metallicum and lactose T2 relaxation times were very similar, except for Zincum metallicum 8dH, which presented a value of 1.226 in comparison to 1.036 of lactose 8dH. The following T2 values were registered: 1.287 - 9dH; 1.413 - 10dH; 1.467 - 11dH, and 1.303 - 9dH; 1.400 – 10dH; 1.350 -11dH, for Zincum metallicum and lactose, respectively. The differences detected in 8dH samples are probably due to the presence of lactose in the first dilution step, in which 1 part of the 6dH triturated mixture was diluted in 9 parts of water, to prepare 7dH. Following this homeopathic procedure, 8dH solutions remain around 1% of lactose which could be influenced by the T2 values registered. Conclusion: These preliminary results showed the possibility to apply the NMR technique to evaluate the influence of dynamization in the relaxation parameters. Further studies should be carried out with other potencies and/or other homeopathic substances, in addition to the evaluation of T1 and the T1/T2 parameters, as previously described by other groups.
In vitro evaluation of Sporothrix brasiliensis biotherapic
Authors: Barbosa Gleyce Moreno , Brito Amanda Ribeiro Ricardo , Souza Lais Cavalcanti dos Santos Velasco , Baptista Andrea Regina de Souza
Published: May 2022

Background: Sporothrix brasiliensis is one of the most virulent zoonosis which affects animals and humans. This fungus is responsible for subcutaneous infection and its contamination is possible through trauma to the skin. Sporotrichosis is highly prevalent in feline. And Rio de Janeiro appears to have the highest occurrence of cases. Objectives: This study aims to evaluate the in vitro efficacy of Sporothrix brasiliensis biotherapic, with and without an association to allopathic medicine commonly used in the treatment. Methodology: Conidium cells of Sporothrix brasiliensis will be cultured in Potato dextrose agar (PDA) for 5 to 7 days and yeast cells in Brain heart infusion (BHI) for 3 to 5 days. After incubation, the cells will be scraped with a drigalski handle and filtered using cells strainer into a tube and centrifuge for 5 minutes at 3000 RPM. The cells will be resuspended with Phosphate buffered saline (PBS), centrifuge again, and finally resuspended in PBS. After preparing the inocule, the microplates will be prepared. There will be 5 groups in vitro. The first one will be the control group, only fungi. The second will be the treatment of fungi with homeopathic medicine (Sporothrix brasiliensis 30DH). The third group will be the homeopathic medicine in association with itraconazole. The fourth will be the treatment with itraconazole only. And the last group will be the fungi with dynamized distilled water 30DH. Sporothrix brasiliensis 30DH will be prepared according to Brazilian Homeopathic Pharmacopeia. Results and discussions: The experiments are still in progress and the results will be analyzed through Analysis of variance (ANOVA) to determine statistically significant differences. Previous articles based on biotherapic treatments demonstrated successful results, so our research group is conducting these experiments to evaluate the effect in this model. Conclusion: Experiments will be made to verify the efficacy of biotherapic on sporotrichosis treatments.
Les navigations intérieures : repenser les mobilités à partir d’une perspective aquatique
Authors: DAFFE Laurie
Published: May 2022

Ce chapitre traite de la navigation. Cette approche demeure encore peu explorée dans la littérature au sujet de la mobilité. En adoptant cette perspective originale, Laurie Daffe met l’accent sur les enjeux sociétaux et environnementaux afférents aux navigations intérieures ainsi que les espoirs portés par le report modale. Ce chapitre montre aussi que les mobilités aquatiques sont un champ de recherche en pleine expansion à la fois dans les domaines de la sociologie, de l’anthropologie et plus généralement des transports.
Aménager l’espace pour la marche comme premier mode de déplacement
Authors: LORD Sébastien , LOISELLE Mathilde
Published: May 2022

Ce chapitre aborde la marche dans l’espace urbain à partir du marcheur et de la marchabilité des espaces en discutant trois perspectives : la première sur la diversité des approches de recherche sur la marche. La deuxième partie sur les déterminants physico-spatiaux de marchabilité confrontés aux perceptions et aux émotions des marcheurs. La troisième, conclusive, met en avant les défis des échelles d’analyse dans une perspective d’intervention sur les milieux de vie.
Les architectures de l’Edge
Authors: AL AGHA Khaldoun , LOYGUE Pauline , PUJOLLE Guy
Published: May 2022

Ce chapitre traite de l’architecture de l’Edge. Il aborde le problème du positionnement des services réalisés sous forme de machines virtuelles sur les trois niveaux de l’Edge Networking. Il décrit le découpage des services en microservices qui sont eux-mêmes intégrés dans des conteneurs. Enfin, il aborde les problèmes de sécurité à mettre en place et l’internet participatif qui intègre les équipements utilisateur pour participer à l’Edge.
Quantification of methane emissions from hotspots and during COVID-19 using a global atmospheric inversion
Authors: McNorton Joe , Bousserez Nicolas , Agustí-Panareda Anna , Balsamo Gianpaolo , Cantarello Luca , Engelen Richard , Huijnen Vincent , Inness Antje , Kipling Zak , Parrington Mark , Ribas Roberto
Published: May 2022

Abstract. Concentrations of atmospheric methane (CH4), the second most important greenhouse gas, continue to grow. In recent years this growth rate has increased further (2020: +15.6 ppb), the cause of which remains largely unknown. Here, we demonstrate a high-resolution (∼80 km),
short-window (24 h) 4D-Var global inversion system based on the ECMWF
Integrated Forecasting System (IFS) and newly available satellite observations. The largest national disagreement found between prior (5.3 Tg per month) and posterior (5.0 Tg per month) CH4 emissions is from China, mainly attributed to the energy sector. Emissions estimated from our global system are in good agreement with those of previous regional studies and point source-specific studies. Emission events (leaks or blowouts) > 10 t CH4 h−1 were detected, but without appropriate prior uncertainty information, were not well quantified. Our results suggest that global anthropogenic CH4 emissions for the first 6 months of 2020 were, on average, 470 Gg per month (+1.6 %) higher than for 2019, mainly attributed to the energy and agricultural sectors. Regionally, the largest increases were seen from China (+220 Gg per month, 4.3 %), with smaller increases from India (+50 Gg per month, 1.5 %) and the USA (+40 Gg per month, 2.2 %). When assuming a consistent year-on-year positive trend in emissions, results show that during the onset of the global slowdown (March–April 2020) energy sector CH4 emissions from China increased above expected levels; however, during later months (May–June 2020) emissions decreased below expected levels. Results for the first 6 months of 2019/20 suggest that the accumulated impact of the COVID-19 slowdown on CH4 emissions from March–June 2020 might be small relative to the long-term positive trend in emissions. Changes in OH concentration, not investigated here, may have contributed to the observed growth in 2020.
Divergence of apparent and intrinsic snow albedo over a season at a sub-alpine site with implications for remote sensing
Authors: Bair Edward H. , Dozier Jeff , Stern Charles , LeWinter Adam , Rittger Karl , Savagian Alexandria , Stillinger Timbo , Davis Robert E.
Published: May 2022

Abstract. Intrinsic albedo is the bihemispherical reflectance independent of effects
of topography or surface roughness. Conversely, the apparent albedo is the
reflected radiation divided by the incident and may be affected by
topography or roughness. For snow, the surface is often rough, and these two
optical quantities have different uses: intrinsic albedo is used in
scattering equations whereas apparent albedo should be used in energy
balance models. Complementing numerous studies devoted to surface roughness
and its effect on snow reflectance, this work analyzes a time series of
intrinsic and apparent snow albedos over a season at a sub-alpine site using
an automated terrestrial laser scanner to map the snow surface topography.
An updated albedo model accounts for shade, and in situ albedo measurements
from a field spectrometer are compared to those from a spaceborne
multispectral sensor. A spectral unmixing approach using a shade endmember
(to address the common problem of unknown surface topography) produces grain
size and impurity solutions; the modeled shade fraction is compared to the
intrinsic and apparent albedo difference. As expected and consistent with
other studies, the results show that intrinsic albedo is consistently
greater than apparent albedo. Both albedos decrease rapidly as ablation
hollows form during melt, combining effects of impurities on the surface and
increasing roughness. Intrinsic broadband albedos average 0.056 greater than
apparent albedos, with the difference being 0.052 in the near infrared or
0.022 if the average (planar) topography is known and corrected. Field
measurements of spectral surface reflectance confirm that multispectral
sensors see the apparent albedo but lack the spectral resolution to
distinguish between darkening from ablation hollows versus low
concentrations of impurities. In contrast, measurements from the field
spectrometer have sufficient resolution to discern darkening from the two
sources. Based on these results, conclusions are as follows: (1) impurity estimates
from multispectral sensors are only reliable for relatively dirty snow with
high snow fraction; (2) a shade endmember must be used in spectral mixture
models, even for in situ spectroscopic measurements; and (3) snow albedo
models should produce apparent albedos by accounting for the shade fraction.
The conclusion re-iterates that albedo is the most practical snow
reflectance quantity for remote sensing.
GENRE ESSENCE OF THE PIANO CONCERTO THROUGH THE PRISM OF MUSICOLOGICAL RESEARCH
Authors: Vardanyan Alyona
Published: May 2022

The article analyzes the genre essence of the piano Сoncerto presented through the prism of Russian musicological studies. The specifics of this genre are considered, its characteristic features are revealed, a panorama of scientific works on the piano Сoncerto in the works of Western European and Russian composers is presented. The conclusion is made about the development of scientific definitions of concertation, timbre personification, etc.
INDICATORS OF FERTILITY OF SOVIET CHINCHELLA RABBITS AND THE DEVELOPMENT OF THEIR OFFSPRING IN THE URALS
Authors: Rustenov A.R. , Demeugaliyev Ye.T. , Еleugaliyeva N.Zh.
Published: May 2022

The conducted studies established that the fertility of young rabbits,for one okrol brought 6.28 rabbits, their survival rate on the 21st day was 92.7%. During the year, the rabbits were bred 6.05 times, the total number of rabbits was 32-33 heads. The live weight at birth of rabbits is 68.9-69.2 g, on the 21st day an average of 279.3 g, the growth rate of 0-150 days was 54.07 times. In winter, the body temperature was 37.50 C, in summer 38.90 C, the respiratory rate was 56.7 and the pulse rate was 142.5 minutes. Hematological parameters of young animals were determined and established: hemoglobinins 96.05 g/l, erythrocytes 7.98 1012 /l and leukocytes 6.49109 / ml, blood biochemical parameters: total proteins 96.88%, albumins 47.86%, gamma-globulins 21.89%, beta-globulins 13.92%, alpha-globulins 10.21%. In young rabbits, the ratio of calcium to phosphorus was 1.81. Concluding the study, we note a high multiplicity of rabbits, intensive growth of young animals, therefore they can be grown in farms in the Urals.
CREATING CONDITIONS FOR REALIZING THE POTENTIAL OF STUDENTS IN THE PROCESS OF TEACHING CHEMISTRY
Authors: Nakhmatulina A.R.
Published: May 2022

This paper discusses the conditions for realizing the potential of future technologists at the educational level of secondary vocational education in the process of teaching chemistry: organization of the learning process, taking into account the characteristics of chemical training of students; use in the educational process of techniques for creating a situation of success. Contributing to the realization of the potential of students, it is possible to achieve good results in their professional training.
COMPARATIVE LEGAL DESCRIPTION OF THE US DECLARATION OF INDEPENDENCE AND THE DECLARATION OF HUMAN AND CITIZEN RIGHTS
Authors: Bahmudov Dzhamalutdin Magomedovich
Published: May 2022

This article reveals the historical significance of the two most important legal acts of the United States and France through their comparison. In fact, they are the basis for the formation of the constitutional legislation of the two countries, and the Declaration of the Rights of Man and Citizen is today an integral part of the French Republic. It also analyzes the reasons for the emergence of documents, the historical context and how they influenced the development of the statehood of the United States and France.
ELASTIC-PLASTIC DEFORMATION OF A CONTAINER IN HIGH-PRESSURE DEVICES WITH PROFILED ANVILS, CALCULATION OF THE BEARING CAPACITY OF THE COMPACTION IN A KONAK TYPE DEVICE
Authors: Nikolaev Nikolai Alexandrovich
Published: May 2022

The process of creating pressure in devices with profiled anvils is associated with elastic-plastic deformation of the material of the container-gasket, located between the punches of the chamber, as they approach each other under the action of the press load. The useful volume of the chamber, the high pressures obtained in it, the strength qualities of the punches and the bearing capacity of the gasket directly depend on the nature of the profiling of the working surfaces of the chamber punches facing each other. The proposed work presents an assessment of the geometric parameters of the profiling of the punches of the high-pressure chamber of the «Konak» type.
PISTON PUMPS
Authors: Salameh Ali , Yakovenko Alexander Valerievich
Published: May 2022

In this article, a description of piston pumps is made, the design of pumps is studied, the scope of application of pumps is considered, the study of malfunctions and recommendations for operation.
Quinto de Esmirna IX 172 ss.
Authors: Gil Juan
Published: May 2022

Discusión de los problemas textuales del verso 174 del libro cuarto de los Posthomerica de Quinto de Esmirna.
Autógrafos femeninos, maridos ausentes y reclusiones religiosas en el Egipto de época ptolemaica: traducción y comentario del papiro UPZ I 59
Authors: Martos Fornieles Marina
Published: May 2022

Junto a la traducción, la primera que se hace al español, ofrecemos un amplio comentario del papiro UPZ I 59, en el que tratamos de enmarcar la carta en su contexto histórico y analizar sus aspectos más problemáticos, como su datación, la cuestión de su autoría y especialmente el concepto central de ἐγκατοχή, cuyas diversas interpretaciones repasamos.
Sobre el teónimo lusitano Labbo
Authors: Luján Martínez Eugenio R.
Published: May 2022

En una inscripción de Plasencia recientemente publicada se ha propuesto reconocer los teónimos en dativo Solidi, Labbo y Lacissabricobo, el segundo de los cuales está atestiguado también en la inscripción lusitana del Cabeço das Fráguas. Sin embargo, creemos que la interpretación adecuada de esta inscripción debe ser como una secuencia de fórmula onomástica personal con genitivo patronímico Solidi, seguida de un teónimo con su epíteto, ambos en dativo plural (Labbo Lagissabrigobo), lo que implica un cambio respecto del análisis lingüístico tradicional del teónimo Labbo.
La importancia internacional de las lenguas revisitada
Authors: Álvarez Mella Héctor , Moreno Fernández Francisco
Published: May 2022

Este trabajo responde al interés científico y social por el análisis comparado de la importancia internacional de las lenguas. En él se ensaya una clasificación que ordena las propuestas existentes según los criterios en que se basan: la percepción de la importancia, la estimación de la importancia y el cálculo de índices complejos. En segundo lugar, el texto presenta una actualización del índice internacional de las lenguas y de sus indicadores para 2020. Por último, se analizan los resultados del cálculo y se comparan con índices anteriores. El análisis permite describir un panorama lingüístico plural y policéntrico, definido por distintas lenguas internacionales y sus respectivas áreas de influencia y expansión.
La voz del profesorado universitario en las guías docentes: Un análisis de las estrategias de posicionamiento en el área de Didáctica de la Lengua y la Literatura
Authors: Velasco Erlantz , Díaz-Iso Ariane , Larruzea-Urkixo Nerea
Published: May 2022

La guía docente manifiesta la planificación y orientación del proceso de aprendizaje de una asignatura. A pesar de instaurarse en el ámbito universitario hace más de dos décadas y ser un género técnico de referencia en el espacio académico, este no ha recibido especial atención en comparación a otros géneros que circulan en la universidad. Sobre un enfoque lingüístico-discursivo, este estudio analiza las estrategias de posicionamiento del profesorado en guías docentes, así como su estructura retórica, sus propósitos comunicativos y su función comunicativa. Para ello, se analizan 118 guías docentes del área de Didáctica de la Lengua y la Literatura de 67 universidades españolas a través de un análisis de tipo inductivo-deductivo. Los resultados muestran un género donde prevalece el discurso informativo-persuasivo y con una preponderancia de la dimensión jerárquica. Del mismo modo, el género presenta una estructura retórica estable, aunque con un etiquetaje diverso en su entitulación
Las competencias exigidas a los trabajadores de la Industria 4.0: Cambios en la gestión de personas
Authors: Corrales Bonilla Johnatan , Ribeiro Neuza , Gomes Daniel Roque
Published: May 2022

La tecnología avanza de manera exponencial, trayendo consigo una serie de desafíos y cambios para el sector industrial y empresarial. La cuarta revolución Industrial genera problemas políticos, sociales, económicos y en todos los campos a nivel organizacional; dificultades que debemos estar en capacidad de solventarlas, haciendo énfasis en la gestión de personas como un factor importante al considerar el recurso humano como la clave de la competitividad de las empresas. Es así como el principal objetivo de este estudio es identificar las competencias que serán exigidas a los trabajadores para la adopción de la de Industria 4.0, enfocado en la selección, formación y evaluación de personas. Se trata de un estudio cualitativo, en donde participan 21 personas involucradas con la industria, de 18 empresas ecuatorianas, con el fin de encontrar competencias adicionales a las obtenidas de una revisión de literatura; obteniendo con esto 26 competencias críticas divididas en cuatro grupos.
La larga marcha hacia el trabajo formal: el caso de los riders y la ley 12/2021
Authors: Baylos Antonio
Published: May 2022

La adaptación del prototipo normativo de la relación laboral a las transformaciones productivas y organizativas generadas por la digitalización en el mundo del trabajo ha tenido su campo de experimentación a propósito de la calificación jurídica de los riders al servicio de las plataformas digitales de reparto. El artículo describe el proceso que se ha seguido en España a través de las decisiones judiciales, un acuerdo social tripartito y finalmente una norma legal que reconoce la laboralidad de este personal con los derechos individuales y colectivos correspondientes e instaura asimismo un derecho de información de los representantes de los trabajadores sobre los algoritmos que inciden en el acceso al empleo y las condiciones de trabajo. Finalmente, se da cuenta de la propuesta de directiva europea que incorpora estos mismos objetivos al proyecto de regulación del trabajo prestado en plataformas digitales.
Ինչպիսի՞ն է Երևան քաղաքի կառավարման ապակենտրոնացման համակարգը/What is the Decentralization of Governance System of the City of Yerevan Like?
Authors: BARSEGHYAN Araksya
Published: May 2022

The effectiveness of local self-governance in a community depends on many factors, namely the level and peculiarities of decentralized governance in the community. Due to the fact that the city of Yerevan plays a significant role in the socio-economic life of the republic, we consider it possible to single out the system of decentralization of city management as a separate subject of research. Accordingly, this paper presents the peculiarities of administrative and financial decentralization of Yerevan and existing problems.
Արտոնությունների ընդհանրացված և համալրված համակարգը (GSP+) և Հայաստանը/Generalised Scheme of Preferences Plus (GSP+) and Armenia
Authors: TADEVOSYAN Ruzanna
Published: May 2022

The paper discusses the export of Armenian goods to the EU within the framework of the «Generalized Scheme of Preferences (GSP +)», the preconditions for becoming a beneficiary of GSP +, the grounds for the graduation of preferences from January 2022, and its consequences. The graduation of the preferences will mainly affect the export of aluminum foil, knitted garments, ferromolybdenum, fermented beverages and tobacco products. The deprivation of GSP + privileges will lead to exports reduction in the EU in the extent of new tariffs and the price elasticity size of that specific product in the EU market. The products that are exported to the EU are competitive in terms of quality, and the decline in price competitiveness can be mitigated by cost savings and productivity growth.
Եվրոպական միության արդարադատության դատարան. եվրոպական տնտեսական ինտեգրման հիմնասյուն իրավական կառույցը/Court of Justice of the European Union: a Legal Pillar of the European Economic Integration
Authors: HAYRAPETYAN Albert
Published: May 2022

The article discusses the landmark cases of the Court of Justce of the European Union (CJEU), which had a considerable impact on the strength and deepness of European integration. However, to better understand the EU legal order, we will start with the presentation of the peculiarities of the EU legislation and the CJEU structure. The article was summarized by presenting the factors and circumstances that hinder and limit the power of the CJEU.
Զբոսաշրջության հազվադեպ հանդիպող, տարօրինակ և վտանգավոր տեսակները/Rare, Strange and Dangerous Types of Tourism
Authors: TOVMASYAN Gayane
Published: May 2022

As we know, tourism implies visiting a place other than the place of one’s residence for leisure, entertainment, treatment, education and other purposes. In addition to the well-known and popular types of tourism, there is a number of types that, at first glance, may seem strange, dangerous, or just rare. In this paper, 30 types of tourism that can greatly change the reader's perception of tourism are presented. To get new sensations and experiences, many tourists may try the safe types presented here, at the same time staying away from dangerous types of tourism.
Passports of honey produced in western Georgia
Authors: Abashidze Nona , Japaridze Indira , Kharadze Maia , Vanidze Maia , Kalandia Aleko , Davitadze Ruslan
Published: May 2022

The monography is dedicated to the study of chemical composition of several honey varieties produced in wester Georgia using modern analytical methods. The results are used to create passports for these samples that would indicate correlation between the chemical composition of the honey, its plant source and geographical origin. Monography will be interesting for the specialists from the fields of natural science, agriculture and food technology, such as experts, students, farmers, and manufacturers.The above project was fulfilled by financial support of the Georgian National Science Foundation (Grant AP/96/13 and 216816). Any idea in this publication is possessed by the authors and may not represent the opinion of the Georgian National Science Foundation
The Influence Dimensions of Psychological Capital on Work Engagement
Authors: Rizana Dani , Helmy Irfan , Wahyuni Reni Suci
Published: May 2022

This study aims to examine the relationship between the dimensions of psychological capital (self-efficacy, optimism, hope and resilience) and work engagement. It uses a quantitative approach with a descriptive method. The population and sample were 37 permanent lecturers at Putra Bangsa University. The results show that: (1) self-efficacy has no effect on work engagement; (2) optimism has no effect on work engagement; (3) hope has no effect on work engagement; (4) resilience shows a positive and significant effect on work engagement; and (5) self-efficacy, optimism, hope and resilience simultaneously have a significant effect on work engagement.

Keywords: Psychological Capital, Work Engagement.
Diamond Chisel Utilization and Effect of Feeding on Surface Roughness of AISI 1045 Steel
Authors: Nasution Abdul Haris , Harahap Muksin Rasyid , Napid Suhardi
Published: May 2022

Shape and surface roughness of a product, when it is produced by a lathe, plays an important role because of its friction, wear, lubrication systems, and others. In each workpiece, the result of the machining process has a certain shape and surface roughness such as shiny, smooth, and rough surfaces. The machining process determines the surface roughness at a certain level, where the surface roughness is used as a reference for product evaluation. Machining the surface roughness of a product does not have a small value, but sometimes a product requires a large surface roughness value according to its function.

Keywords: Feeding, surface roughness, AISI 1045, diamond chisel.
Decision-Making Marketing Strategy for Improving PLN Mobile Application Users PT. PLN (Persero) (UP3) Tanjung Karang
Authors: Redaputri Appin Purisky , Rini Yulisa Puspita
Published: May 2022

It can be seen based on existing data that the use of the PLN Mobile application is not maximal among the public; therefore, it is necessary to do the right marketing strategy to maximize the use of the PLN Mobile application at PT. PLN (Persero) UP3 Tanjung Karang considering that technology is getting more advanced from time to time. Soft System Methodology (SSM) and Analytical Hierarchy Process (AHP) are the methods used in this study with a descriptive analysis design through a qualitative approach. The factors that can maximize the increase in PLN Mobile application users are three sub-criteria from internal factors, namely Promotion, Application Infrastructure Improvement, HR, then three sub-criteria from external factors, namely Accessibility, Environmental Change, Public Relations and, four alternatives, namely Collaborating with influencers. (A person to influence decisions to others), Advertising (Making advertising in electronic media or mass media), Improving promotional programs and socializing the use of the PLN Mobile application. The most prioritized alternative for increasing PLN Mobile application users is to socialize the use of the PLN Mobile application to the public.

Keywords: User Increase, Decision Making, PLN Mobile Application, Analytical Hierarchy Process (AHP).
Clitopiloides prati and Trichopilus lecythiformis spp. nov. from Australia
Authors: Largent David L. , Cribari Molly B.
Published: May 2022

Clitopiloides prati (from northeastern Queensland) and Trichopilus lecythiformis (from coastal New South Wales) are described as new entolomatoid species based on morphological characters. Morphological similarities are discussed for these and other closely related species.
We also provide nuclear ribosomal RNA repeat (nrITS) and large subunit (nrLSU) sequences where obtained.
Passalora golaghati comb. nov. from India
Authors: Singh Gargee , Yadav Sanjay , Singh Raghvendra , Kumar Shambhu
Published: May 2022

The hyphomycete Cercospora golaghati is recombined as Passalora golaghati based on critical re-examinations of original type material and a fresh topotypic collection and comparison with closely related species of cercosporoid taxa.
PREPARATION AND CHARACTERIZATION OF SELF-HEALING MAGNETORHEOLOGICAL ELASTOMERS
Authors: Wang J. , Zhang Q. , Lv J. C. , Wei Y. T.
Published: May 2022

Magnetorheological elastomers (MREs) are a kind of active control smart material, and their critical problem is that their ferromagnetic particles are too large, which causes holes to develop and results in MREs with poor mechanical performance and fatigue resistance. In this work, liquid butadiene acrylonitrile rubber (NBR)-synthesized phenolic resin microcapsules were synthesized and applied to MREs as a self-healing agent, effectively reducing the number of holes caused by ferromagnetic particles. The structure of the self-healing agent was determined by Fourier transform infrared (FT-IR) spectroscopy, thermal gravimetric analysis (TGA), and scanning electron microscopy (SEM). The results indicated that a self-healing agent was successfully synthesized, the core of the capsule was spherical liquid nitrile rubber, and the wall of the capsule was composed of phenolic resin microspheres. Furthermore, the SEM images of the MREs showed that the number of cavities caused by ferromagnetic particles was greatly reduced after the addition of the self-healing agent, and the X-ray photoelectron spectroscopy (XPS) results of the MREs indicated the formation of a chemical bond between Fe and O. In addition, the mechanical properties and fatigue resistance of the MRE materials with the self-healing agent were improved. Under 100% strain and with the same number of cycles, the crack growth rate of MREs without self-healing agent is faster by about 329%, and the crack length is longer by about 220% than those of MREs with self-healing agent.
Effectiveness of Techno-Pedagogical Skills of Secondary School Teachers on Online Teaching During Covid-19 Pandemic
Authors: Setua Chiranjit
Published: May 2022

This study investigates the effectiveness of techno-pedagogical skills of secondary school teachers in their online teaching. A sample consists of 42 CBSE and ICSE secondary school teachers. The research adopts a descriptive survey design for collecting data using the “Techno-Pedagogical Skill Assessment Scale” developed by Sibichen (2011). Structured interviews also formed a part of data collection. The results reveal a moderately positive correlation between techno-pedagogical skills and effective online teaching. There is a significant difference between the high level and low level of techno-pedagogical skills of secondary school teachers with their effective online teaching. The positive impact of the COVID-19 pandemic on the techno-pedagogical skill of secondary school teachers is reported in the study.
Valuing Teaching Profession: Exploring Attitude of Pre-Service Teacher Educators
Authors: Devi Sneh , Bakshi Ritu
Published: May 2022

Education plays a significant role in changing the behaviour, perceptions, feelings, and beliefs of the individual. The ability of a teacher to teach is dependent on their attitude toward the profession. The teacher helps create a conducive and learner-friendly atmosphere in the classroom through his attitude. It has a positive impact on the learning ability of children. The quality of education through pre-service and in-service teacher Education Programmes (PIEP) uplifts the standard of education in the whole country. These programmes help to support and develop the necessary pedagogical skills and competencies among teacher educators. The objective of the present study is to measure the attitude of pre- Service teacher educators towards the teaching profession. The sample consists of 30 Teacher educators. The study uses an Attitude towards the teaching profession scale standardized by Tewari to collect data. Statistical measures are employed to find the difference in attitude towards the teaching profession among pre-service teacher educators. The results reveal that significant differences do not exist between the attitude towards the teaching profession and pre-service teachers’ locale. There is a significant difference in attitude towards the teaching profession among pre-service teacher educators concerning their gender.
Individual Differences in Responses to Rhythmic Entrainment in Music and Movement Intervention Among Individuals with Autism
Authors: Chen Yan Yee , Cheong Ku Wing , Chua Yan Piaw
Published: May 2022

This study examines the influence of individual differences in sensory sensitivities and motor functions of four individuals with a spectrum of autistic traits on impacting their responses to the music and movement intervention. A multiple case study approach examines the participants’ individualised responses to rhythmic entrainment during the six-week music and movement intervention. Sensory sensitivities play a vital role in affecting the four participants entraining their body movements to the rhythmic cues, and inducing their auditory-motor mechanism. The findings indicate that each participant with autism has a distinctive response to the rhythmic cues, and this impacts the treatment outcomes of the music and movement intervention. The study recommends future researchers include individual differences in sensory and motor development as part of their investigation. These factors can directly influence the treatment outcomes of music and movement intervention from a neurological aspect.
Datas de semeadura e de transplante para a cultura da cebola baseadas na disponibilidade térmica e fotoperíodo em clima subtropical de Santa Catarina
Authors: Vieira Hamilton Justino , De Menezes Junior Francisco Olmar Gervini , Blainski Everton , Miszinski Joelma
Published: May 2022

O objetivo deste trabalho foi indicar possíveis datas de semeaduras e de transplantes para o cultivar de cebola Empasc352 - Bola Precoce cultivado na região do Alto Vale do Itajaí em Ituporanga, Santa Catarina, baseado na disponibilidade térmica por Graus-dias acima de 15°C e do fotoperíodo. Utilizaram-se 10 datas de semeaduras com intervalos semanais durante quatro anos agrícolas, determinando-se os intervalos em dias para 40 períodos entre semeadura-transplante, semeadura-colheita e transplante-colheita na Estação Experimental de Ituporanga (Epagri/EEItu), em SC. A disponibilidade térmica não inviabilizou o transplante e a colheita ao longo do período de cultvo utilizado. Para a fase semeadura ao transplante, ocorreu uma diminuição dos Graus-dias acumulados a partr da primeira época de semeadura. Ocorreu uma tendência de compensação dos Graus-dias médios diários entre as fases semeadura ao transplante e a fase de transplante à colheita. As épocas de semeadura intermediárias mostraram uma tendência de equivalência da disponibilidade térmica média diária entre as três fases, tendo as épocas de 12/04 a maior igualdade. Baseado nos resultados, podem-se recomendar as semeaduras entre 15 de abril e a primeira quinzena de maio com os transplantes até 24 de agosto, para atender a necessidade térmica do cultvar Empasc 352 - Bola Precoce na região de Ituporanga.
Eficiência de inseticidas no controle do tripes do alho, Thrips tabaci Lindeman
Authors: Lins Junior Juracy Caldeira , Delalibera Geremias Leandro , Pereira dos Santos Janaína , Hahn Leandro , Mallmann Guilherme
Published: May 2022

A eficiência de sete inseticidas (beta-ciflutrina, deltametrina, cloridrato de formetanato, espinetoram, clorfenapir, imidacloprido e acetamiprido + etofenproxi) recomendados para o controle do tripes do alho (Thrips tabaci) foi avaliada em um estudo de campo conduzido em duas safras consecutivas no município de Caçador-SC. Foram realizadas duas aplicações dos inseticidas e as avaliações foram realizadas aos 3 e 7 dias após cada aplicação. A maior redução na população de tripes foi observada nos tratamentos com espinetoram e cloridrato de formetanato seguidos por imidacloprido. Já os inseticidas beta-ciflutrina, deltametrina, clorfenapir e acetamiprido + etofenproxi foram menos efetivos no controle dos tripes nas condições avaliadas. Os inseticidas espinetoram e cloridrato de formetanato foram os inseticidas mais eficientes para o controle de T. tabaci na cultura do alho em Santa Catarina.
Pesticide Exposure and Health Risks: The Case of Pesticide Traders
Authors: O. Esechie Jovita
Published: May 2022

There is a paucity of information worldwide on the health problems among pesticide traders that are occupationally exposed to pesticides. A study was conducted in the Sultanate of Oman to investigate pesticide handling and their health risk perception by pesticide traders, and how these are impacted by their level of education, training, and the use of personal protection equipment (PPE). A total of 63 traders were randomly selected in four Regions (Al Batinah, Al Dhahirah, Al Dakhiliyah and Al Sharqiyah) in the Sultanate of Oman. Participation was based on full informed consent and assurances of confidentiality. The survey adopted the interview format, using hard copies of questionnaires. About 90% of the traders with formal pesticide training used some form of PPE, compared to 19% among those with no pesticide training. All (100%) of the trained traders had knowledge of pesticide regulations, informed customers on the proper use of pesticides and knew that pesticides could be dangerous. The corresponding percentages among the untrained traders were 13, 12 and 60, respectively. Among all the traders, the most reported health symptoms were headache (73%), skin irritation (71.4%) and salivation (63.5%). In as much as many farm workers and other pesticide end-users depend on the traders for information on pesticides, it is suggested that training be made mandatory for all pesticide traders. The use of PPE should also be made mandatory and pesticide inspectors should be made to inspect the pesticide shops regularly to ensure compliance.
Aflatoxin levels in commercial finisher balanced feeds for broilers and pigs from Venezuelan factories
Authors: Fernández Ebbis , Riera-Betancourt José Gregorio , Briceño-Fereira Elena Del Carmen , Comerma-Steffensen Simon Gabriel , Martínez-Camacaro Eduard , Arrieta-Mendoza Darwuin
Published: May 2022

Mycotoxins, even so government regulates to control their levels in animal balance feeds, they could pose a problem to animal and human consumption health. Therefore, the aim was to determine the levels of total aflatoxins found in the finisher balanced feeds for broilers and pigs, produced by balanced feed factories (BFF) in Venezuela. Eleven BFFs were sampled and evaluated for the presence of aflatoxins: AFB1, AFB2, AFG1 and AFG2, determined using the analytical chemical technique HPLC-FLD. Thirty three feed samples for broilers and 33 for pigs, a total of 66 samples were obtained from BFFs. The presence of aflatoxins was detected in 100 % of the finisher balanced feeds for poultry and pigs. The determined AFB1, AFB2, AFG1 and AFG2 levels in finisher balanced feeds for broilers and pigs, rendered that the aflatoxin with the highest concentration was always AFB1. The averages of total aflatoxins detected from finisher feeds for broilers and pigs were within the maximum allowed limits (20 micrograms (μg) / kilograms (kg) of COVENIN standards (Venezuelan regulations). When compared each aflatoxin level (AFB1, AFB2, AFG1 and AFG2) eight out of eleven BFFs evaluated comply with the standard, but 3 (F1, F2 and F5) BFFs were outside (5 μg/kg). It is pertinent that the companies that produce final food for poultry and pigs carry out additional and frequent evaluations of other mycotoxins (Ocratoxins, fusarium mycotoxins and mycotoxins emerging) present in raw materials, in order to evaluate the risks in the agri-food chain, in the way to implement solutions before or after processesment to ensure public health quality.
國內細胞治療的現況、限制與風險
Authors: 何弘能 何弘能
Published: May 2022

隨著醫療科技的快速突破，細胞或基因改造過的細胞治療、再生醫療可解決許多未被滿足的醫療需求，再加上商機無限，已成為近10年進展最快的一種治療方向。細胞治療具有許多限制及挑戰，從研發、製備場所、供應、臨床試驗、治療到追蹤，皆與藥物管理有很大差異，無法依相同法規或規範執行。而法規齊備、專業人才培育與延攬、降低費用及結合AI科技等，都是細胞治療成功的關鍵。如何讓有需求的病人能順利、安心的接受治療，而不只是「富人醫療」，是我們最大且重要的期望及目標。

 

As medical technology advances rapidly, cell therapy and regenerative medicine involving cells or genetically-modified cells can address many unmet medical needs. They have infinite commercial opportunities and have become the one of the most rapidly developing directions for therapy in the last decade. Cell therapy is under various limitations and faces numerous challenges. The research and development, preparation sites, supplies, clinical trials, treatments, and follow-up procedures of cell therapy differ greatly from medicine management; thus, the regulations or norms for medicine management cannot be applied to cell therapy. The keys to successful cell therapy include comprehensive legislation, cultivation and recruitment of professionals, cost reduction, and integration with artificial intelligence technologies. To enable patients in need to smoothly receive cell therapy at ease, making cell therapy affordable to all people is our primary and most critical expectation and goal.

 
Implementasi Metode Cooperative Integrated Reading and Composition (CIRC) untuk Meningkatkan Keterampilan Menulis Siswa
Authors: Bili Kristoforus Dowa
Published: May 2022

Abstrak: Penelitian ini bertujuan untuk meningkatkan keterampilan menulis siswa kelas VA SD Negeri Depok 1 Kabupaten Sleman melalui implementasi metode Cooperative Integrated Reading and Composition (CIRC). Penelitian dilakukan di SD Negeri Depok 1 Kabupaten Sleman. Jenis penelitian yang digunakan adalah Penelitian Tindakan Kelas. Subjek dalam penelitian ini adalah siswa kelas VA SD Negeri Depok 1 yang berjumlah 30 orang, dengan rincian 12 pria dan 18 wanita. Objek penelitian adalah pembelajaran Bahasa Indonesia aspek menulis dengan menerapkan metode CIRC. Pengumpulan data dilakukan dengan teknik tes, berupa tes menulis karangan dan teknik nontes berupa observasi, wawancara, dan dokumentasi. Data yang berhasil dikumpulkan, dianalisis secara objektif dan kritis secara deskriptif kualitatif dan kuantitatif dengan memberi penekanan perbandingan antara tindakan prasiklus, siklus I, dan siklus II. Indikator keberhasilan penelitian adalah 85% siswa mencapai nilai minimal sesuai KKM, yaitu 60 dan siswa lebih aktif dalam proses pembelajaran. Hasil penelitian menunjukkan bahwa implementasi metode CIRC dapat meningkatkan keterampilan menulis siswa kelas VA SD Negeri Depok 1 Kabupaten Sleman. Keterampilan menulis siswa mengalami peningkatan setelah pelaksanaan tindakan siklus I dan siklus II. Rata-rata keterampilan menulis siswa pada prasiklus hanya mencapai angka 59,1 (kategori kurang). Pada siklus I mengalami peningkatan menjadi 64,8 (kategori cukup) dan pada siklus II meningkat menjadi 74,8 (kategori baik). Nilai rata-rata meningkat sebesar 15,7 dari prasiklus ke siklus II. Jumlah dan persentase siswa yang mencapai angka KKM pada prasiklus hanya 13 (43,3%). Pada siklus I menjadi 21 (70%) dan pada siklus II meningkat hingga terdapat 29 (96,7%) siswa yang mencapai angka KKM. Dengan demikian, dapat dikatakan bahwa penelitian tindakan kelas telah berhasil dalam meningkatkan keterampilan menulis siswa dengan menerapkan metode CIRC.Kata kunci: Implementasi; Metode Cooperative Integrated Reading and Composition (CIRC); Keterampilan menulis.