bluuebunny/crossref_metadata_2025 huggingface dataset:
Experimental and Finite Element Investigations on the Biomechanical Consequences of Meniscectomies in the Knee Joint: A Narrative Review
Authors: Devaraj Ashwin Kumar , Acharya Kiran Kumar V. , Adhikari Raviraja
Published: April 2023

Background:

The knowledge of the complex biomechanical behaviour of the meniscectomised knee joints is of paramount importance in various clinical situations. A combined review of experimental and finite element analysis studies examining the consequences of meniscectomies on the biomechanics of the knee joint has not been reported in the literature. Therefore, this paper presents a combined review of experimental and finite element analysis studies on the biomechanical consequences of medial and lateral meniscectomies in the knee joint.

Methods:

Experimental and FEA investigations on the association between meniscectomies and the biomechanical response of the knee joint are reviewed. The effects of partial and total meniscectomies in the medial and lateral compartments are included in this paper.

Results:

Subtotal/total medial meniscectomies cause a significant decrease in the contact area and a substantial increase in the contact stress in comparison with that in an intact knee joint. This could give rise to severe degeneration of the cartilage surface. Partial medial meniscectomy causes a modest reduction in the contact area associated with a moderate increase in contact stress. The resection of both leaflets of the meniscus results in a substantial increase in the contact pressure and a significant reduction in contact area compared with inferior leaflet resection.

Conclusion:

This review recommends partial medial meniscectomy over subtotal/ total medial meniscectomy. It also suggests performing resection of the inferior leaflet rather than resection of both the leaflets. Finally, some recommendations for future work are suggested to predict the realistic biomechanical behaviour of meniscectomised knee joints.
ОЦІНКА ВПЛИВУ ПЕРЕДОПЕРАЦІЙНОГО ПРИЗНАЧЕННЯ АМІНОКАПРОНОВОЇ КИСЛОТИ НА ПЕРЕБІГ ПІСЛЯОПЕРАЦІЙНОГО ПЕРІОДУ У ПАЦІЄНТІВ ІЗ НАЗАЛЬНИМ ПОЛІПОЗОМ
Authors: І.В. Кошель  , Я.Р. Максименко
Published: April 2023

Хронічний риносинусит з назальним поліпозом (ХРСзНП) за домінуючим ендотипом включає еозинофільний, який є найтяжчим варіантом. Пацієн- ти, як правило, мають більш тяжкий клінічний перебіг, поліпи ростуть швидко і часто рецидивують. Основним методом оперативного лікування є функціональна ендоскопічна ендоназальна хірургія. Особливості ендоти- пу ХРСзНП обґрунтовують використання амінокапронової кислоти (АКК) для передопераційної підготовки. Метою дослідження є оцінити вплив передопераційного призначення АКК на перебіг раннього післяопераційного періоду у порівнянні з пацієнтами, які отримують стандартну терапію ХРСзНП згідно клінічних рекомендацій. У дослідження включено 120 пацієнтів, розділених на дві групи: основну (n - 60) і контрольну (n - 60). Пацієнтам призначалось базове лікування (іригаційна терапія сольовими розчинами та мометазону фуроат), а в основній групі додатково АКК. Пацієнтам, які підялягали хірургічному лікуванню, проводилась FESS. Для визначення особливостей післяопераційного періоду відібрано 20 пацієнтів – по 10 із кожної групи. Проводився аналіз носового дихання та транспортної функції миготливого епітелію порожнини носа

Використання АКК при ХРСзНП сприяє достовірному зменшенню кількості прооперованих пацієнтів: необхідність хірургічного втручання в основній групі була у 56,7% пацієнтів і 81,7% у контрольній. Результати аналізу динаміки відновлення носового дихання та мукоциліарного кліренсу продемонстрували, що сьома доба післяопераційного періоду завершилось практично повним відновленням носового дихання та транспортної функції миготливого епітелію порожнини носа пацієнтів дослідної і контрольної групи. Відмінності в перебігу післяопераційного періоду статистично не достовірні. Використання АКК додатково до базової терапії пацієнтам, хворим на ХРСзНП на 25% зменшує необхідність хірургічного лікування.

 

Не відмічено впливу додактвового призначення АКК в передопераційному періоді на перебіг післяопераційного періоду у оперованих пацієнтів.

Ключові слова: Поліпозний риносинусит, амінокапронова кислота, хірургічне лікування.
The Influence of Paid Memberships on Physician Rating Websites With the Example of the German Portal Jameda: Descriptive Cross-sectional Study (Preprint)
Authors: Armbruster Friedrich Aaron David , Brüggmann Dörthe , Groneberg David Alexander , Bendels Michael
Published: April 2023

BACKGROUND

The majority of Germans see a deficit in information availability for choosing a physician. An increasing number of people use physician rating websites and decide upon the information provided. In Germany, the most popular physician rating website is Jameda.de, which offers monthly paid membership plans. The platform operator states that paid memberships have no influence on the rating indicators or list placement.

OBJECTIVE

The goal of this study was to investigate whether a physician’s membership status might be related to his or her quantitative evaluation factors and to possibly quantify these effects.

METHODS

Physician profiles were retrieved through the search mask on Jameda.de website. Physicians from 8 disciplines in Germany’s 12 most populous cities were specified as search criteria. Data Analysis and visualization were done with Matlab. Significance testing was conducted using a single factor ANOVA test followed by a multiple comparison test (Tukey Test). For analysis, the profiles were grouped according to member status (nonpaying, Gold, and Platinum) and analyzed according to the target variables—physician rating score, individual patient’s ratings, number of evaluations, recommendation quota, number of colleague recommendations, and profile views.

RESULTS

A total of 21,837 nonpaying profiles, 2904 Gold, and 808 Platinum member profiles were acquired. Statistically significant differences were found between paying (Gold and Platinum) and nonpaying profiles in all parameters we examined. The distribution of patient reviews differed also by membership status. Paying profiles had more ratings, a better overall physician rating, a higher recommendation quota, and more colleague recommendations, and they were visited more frequently than nonpaying physicians’ profiles. Statistically significant differences were found in most evaluation parameters within the paid membership packages in the sample analyzed.

CONCLUSIONS

Paid physician profiles could be interpreted to be optimized for decision-making criteria of potential patients. With our data, it is not possible to draw any conclusions of mechanisms that alter physicians’ ratings. Further research is needed to investigate the causes for the observed effects.
Machine Learning Models to Predict the Warfarin Discharge Dosage Using Clinical Information of East Asian Inpatients: Retrospective Cohort Study (Preprint)
Authors: Choi Heejung , Kim Young-Hak , Jun Tae Joon , Kang Hee Jun , Ahn Imjin , Gwon Hansle , Kim Yunha , Seo Hyeram , Cho Ha Na , Kim Minkyoung , Han JiYe , Kee Gaeun , Park Seohyun , Kwon Osung , Roh Jae-Hyung , Kim Ah-Ram , Kim Ju Hyeon
Published: April 2023

BACKGROUND

As warfarin has a narrow therapeutic window and obvious response variability among individuals, it is difficult to rapidly determine personalized warfarin dosage. Adverse drug events resulting from warfarin overdose can be critical. Our study aimed to develop a machine learning (ML) model that predicts the appropriate discharge dosage of warfarin using electronic medical records from a large hospital. Additionally, we externally validated the model to ensure its accuracy.

OBJECTIVE

This study aimed to develop a machine learning model that predicts individual warfarin dosage based on clinical data within 2 days of hospitalization.

METHODS

During this retrospective study, adult patients who were prescribed warfarin at a large hospital between January 1, 2018, and October 31, 2020, were recruited as a model development cohort (n=3,168). We externally validated the models using the Medical Information Mart for Intensive Care III (n=891). Variables for the warfarin dosage prediction were selected according to the clinical practice experience of cardiovascular physicians. The study outcome was the warfarin discharge dosage. Four ML models that predicted the proper warfarin discharge dosage were developed. We evaluated the model performance using the mean absolute error (MAE) and prediction accuracy. Finally, we compared the accuracy of the predictions of our models and the predictions of physicians to determine their clinical relevance.

RESULTS

The MAEs obtained using the internal validation set were as follows: XGBoost, 0.9; neural network, 0.9; random forest, 1.0; linear regression, 1.0; and physicians, 1.3. These values showed that our models had better prediction accuracy than the physicians, who have difficulty determining the warfarin discharge dosage using clinical information obtained within 2 days of hospitalization.

CONCLUSIONS

Our ML model could help physicians rapidly predict and decide the proper warfarin discharge dosage during hospitalization. Further work is required to determine model generalizability.
Cigarette smoking and duration of sun exposure as risk factor for cataract formation
Authors: Christine Reinne Natali , Serapina Abigail , Simanjuntak Gilbert , Tan Janes Fritz
Published: April 2023

Cataract is the most common cause of vision loss in Indonesia. It involves many risk factors, such as age, trauma, persistent intra-ocular inflammation, ultraviolet radiation, diabetes mellitus, hypoparathyroidism, prolonged corticosteroid administration, and high body mass index. However, the role of smoking and sun exposure in cataracts has received less attention despite of the high number of cigarette smokers in Indonesia and this country also has strong sunshine all year round. The aim of this study was to investigate the relationship of cigarette smoking and duration of sun exposure with senile cataracts in Jakarta, Indonesia. This was a cross-sectional study without knowing risk factor before. A total of 100 patients participated in this study selected with consecutive sampling technique. They were divided into two groups: first was the case group consisting of 50 subjects aged more than 40 years old and diagnosed with senile cataracts and the second was the control group consisting of subjects aged more than 40 years old without cataract disease. All participants had to complete the questionnaire related to the history of smoking and duration of outdoor activity per day as it related to sun exposure. The sample was taken from the eye screening program in Puskesmas Cawang, East Jakarta. This research discovered a relationship between cigarette smoking and duration of sun exposure more than seven hours per day with the incidence of senile cataract (p=0.001) Statistical tests also showed an association between smoking duration more than 20 years and incidence of senile cataract (OR 7.25, 95% CI: 1.43 - 36.6; p = 0.02). However, the results revealed that there was no relationship between the number of cigarettes smoked per day with the incidence of senile cataract (p = 0.915). Overall, cigarette smoking and its duration appear to increase the risk of senile cataract formation.
COVID-19 and health behaviors of the vulnerable group in the disaster-prone area:a case study of volcano-prone Merapi, Indonesia
Authors: Dewanti Diah Setyawati , Hartarto Romi Bhakti
Published: April 2023

As the world’s fourth most populous country, Indonesia is predicted to suffer greatly from the pandemic. One of the most vulnerable groups in Indonesia is those living in the disaster-prone areas where access to health services is limited. This study aims to identify whether households in the disaster-prone area were already aware of and have implemented protective health behaviors during the COVID-19 pandemic. The location of the study was at Dongkelsari settlement houses in the Disaster-Prone Area III of Mount Merapi, the most active volcano in Indonesia. Descriptive statistics were used to summarize the quantitative data collected from face-to-face interviews with 142 out of 161 households residing in that area. Our findings suggest that knowledge about disease and prevention is quite high in our sample. More than 90% of the sample were already aware of COVID-19 transmission and understood that washing hands and wearing facemasks can prevent the spread of COVID-19. This high level of awareness is inseparable from the active role of community leaders in Dongkelsari area. However, only less than half of the sample reported practicing safe physical distancing. In conclusion, our study relies on field observation, and this complements the existing evidence by capturing a clearer picture of the COVID-19 awareness among the underrepresented population living in the disaster-prone area of Merapi volcano.
DRUG PRESCRIBING PATTERN OF VARIOUS ANTIFUNGAL DRUGS FOR DERMATOPHYTOSIS IN A TERTIARY HEALTHCARE AND TEACHING HOSPITAL
Authors: KUSHWAHA VIRENDRA , AGRAWAL POOJA , FATMA KHAN NASREEN , SHIVHARE DEV PRAKASH , KUMAR AMIT , SHARMA HIMANSHU
Published: April 2023

Objective: To analyze the pattern of drug prescription and the rationality of pharmacotherapy used in dermatophytosis.
Methods: A prospective observational study was conducted from January 2021 to June 2022 in the Department of Skin and Venereal Diseases. Prescriptions included all newly diagnosed patients with cutaneous fungal infections of both genders who attended Dermatology OPD. Factors considered were sociodemographic parameters, clinical manifestations, combination and monotherapy along with prescribed topical and systemic agents, and details of prescribing indicators.
Results: A total of 362 dermatophytosis cases were observed, which included 230 males and 132 females. Patients in the age group of 13-40 y (65.47%) have shown the dominance of dermatophytosis infection with a high prevalence among the student category, which accounts for 177. Tinea corporis (40.85%) was the prominent clinical manifestation of dermatophytosis infection. Among single topical agents, the most commonly prescribed drug is Clotrimazole (15.19%), and among topical combinations, sertaconazole and ketoconazole (29.28%). Itraconazole (48.75%) is the most commonly used oral formulation, followed by the itraconazole and terbinafine combination (22.56%). While imidazoles were the maximally prescribed topical antifungals according to the therapeutic class.
Conclusion: Tinea corporis is the prominent clinical manifestation and the majority of prescriptions were for a combination of three agents mainly oral itraconazole with topical sertaconazole, and ketoconazole.
An IoT-Based Parking System to Prevent Unauthorized Vehicles
Authors: Chaitanya Karna , Madhavi B.
Published: April 2023

Abstract: In India, a family needs at least two cars since traffic congestion has become a serious problem, therefore parking space is at a premium, which means the emptor is less of a need. Because all work nowadays has been done online, an IoT-based smart parking system is the only viable option. By utilizing IoT sensors to detect and monitor security, locate parking lots, and reserve spaces, the smart parking system can make parking easier and more convenient for all users, thereby showing how the IoT can be widely used by a wide range of people in their everyday lives to make life easier and more convenient. To lessen traffic and make parking simpler, low-cost technology is being used. By minimizing traffic congestion and requiring less time for parking. In the smart parking system, information about the parking area is gathered through a website, and parking spaces may be reserved and tagged. RFID Tag reader reads the tags on the cars in the parking lot's designated area, which are subsequently displayed on the LCD screen and the main gate. A specific parking lot has been reserved for the automobile. Programming an IoT product using the Arduino IDE software on an Arduino Nano based on automated parking system control using codes is made simple and powerful using the ESP8266. The most important benefit is that it saves time and money, and provides security control.
Crossover to Crypto Currency Using E-RUPI
Authors: Pathak Jayeshkumar Narendra , Bhaduri Soudip
Published: April 2023

Abstract: Crypto currencies have recently gained a lot of attention from investors, central banks and governments, On August 2 2022, the Prime Minister, Shri Narendra Modi launched a digital payment solution e-RUPI, a cashless and contactless instrument for digital payments. He said that e-RUPI is a symbol of how India is progressing by connecting people’s lives with technology. This paper Reviews and surveys popular way of Exploring Opportunities and the Impact on Business Specifically on Rural and Urban Retail Business World, to provide a technical overview of e-Rupi, outline open challenges, and review the Fundamental Questions like Digital Wallet Holder can have equal Anonymous transaction Benefit as Physical Currency. As we all are living in a 21st century known as a technological era. In this as per various observation researcher focused on holistically Awareness and Acceptance of the e-rupi
“Janani” The Farming Robot
Authors: Srivastava Vinayak
Published: April 2023

Abstract: Farmers and farm workers suffer from increased rates of respiratory diseases, noise-induced hearing loss, skin disorders, certain cancers, chemical toxicity, and heat-related illnesses. Organic Dust Toxic Syndrome (ODTS) is a common respiratory illness manifested by temporary influenza-like illness with fever, headache, and muscle aches and pains. Contact dermatitis is a skin disorder that occurs among agricultural workers. Heat stress occurs when the body builds up more heat than it can handle. High temperatures, high humidity, sunlight, and heavy workloads increase the likelihood of heat stress. So, the Janani bot will perform all the farming practices like Ploughing, Sowing, Levelling, Irrigation, Harvesting and Soil Moisture Monitoring. Which will help reducing the human effort and prevent them from many of the health issues cause during performing the farming practices.
Real Time Risk Prediction of heart patients using HRV and IoT: A Survey
Authors: Boricha Siddhesh , Bankar Shivam , Kamble Vijay , Salgaonkar Prathamesh , Deore Manasi N
Published: April 2023

Abstract: In today's world, the leading cause of death is heart disease. The term heart disease is described as several different conditions that affect the heart. There are many types of heart disease, but the most common are coronary heart disease, congestive heart failure, and arrhythmia. Currently, the healthcare system is hospital essential which is inefficient to treatthese conditions, which require immediate assistance. This is a roundabout way to point to a rise in the death rates. Heart rate variability (HRV) is a useful tool for identifying and monitoring potential risk factors for heart disease. HRV measures the time between each heartbeat and can be used to identify subtle changes in heart rate that may be indicative of an underlying health condition. With the help of Machine learning and (Internet of Things) IoT-based heart patients real-time monitoring and predicting risk analysis will enable doctors to view patient's health status online. Internet of Things (IoT) technology to continuously track and monitor vital signs,including heart rate, pulse rate, and body temperature. In addition to these traditional vital signs, the system also includes afeature for monitoring heart rate variability (HRV), which has been shown to be a useful indicator of heart disease risk prediction. Using machine learning and HRV capabilities, the system will be able to assess health status and anticipate patient'sheart health (low-risk or high-risk) based on the ECG waveform and HRV characteristics such as time domain and frequency domain values
Biostatistical Analysis of Relation between HLA-A/B and HLA-DR Eplet Mismatches and Renal Graft Outcome
Authors: Asokan Nidheesh Roy Trikariyoor , Aziz Feroz , Kozhiyil Elyas Kothanam
Published: April 2023

Abstract: Despite all the clinical interventions that happened during the last 2 decades, the unavailability of a potent donor for renal transplantation remains a concern in the field of transplantation immunology. Recent studies promise the establishment of an effective clinical method to find a potent renal transplant donor, in the near future. Combining the use of molecular techniques with biostatistical methods can be a great tool for clinicians in choosing a potent donor. The present study was conducted from a cohort of 1144 (n=572 pair) renal transplant recipients and their donors to analyse eplet matches and mismatches. Initial observation of increased serum creatinine level which ranged from 2.0 to 21.0 mg/dL in patients treated for end-stage renal disease implied a single event of graft rejection. The statistical correlation between eplet mismatches and graft survival was observed to be significant with P value 0.003. A value of -0.215 at 0.01 significance showed the positive linear correlation between the increased numbers of HLA DR eplet mismatches towards chronic renal graft rejection. The correlation coefficient of -0.888 observed between the number of HLA DR eplet mismatches and days of graft survival clearly implies the effect of increased HLA DR eplet mismatch delayed graft rejection. The study gives an idea on the minimization of class II HLA DR eplet mismatches to decreased frequency of graft rejection as indicated by increased survival rate.
SISTEM ANDROID MONITORING HAMA DAN PENYAKIT PADA PERKEBUNAN KELAPA SAWIT
Authors: Susanto Agus , Eko Prasetyo Agus , Prawiratama Hari , Loren Yopi , Perdana Rozziansha Tjut Ahmad
Published: April 2023

Salah satu keberhasilan pengendalian hama dan penyakit di perkebunan kelapa sawit adalah penerapan sistem monitoring atau sensus hama dan penyakit. Sistem yang selama ini dikembangkan yaitu berdasarkan pengamatan dan pencatatan manual oleh petugas hama. Sistem baru yang dikembangkan yaitu menggunakan sistem teknologi informasi berbasis smartphone android. Aplikasi android yang dikembangkan untuk pencatatan sistem monitoring ini bernama Monitoring HPT Sawit yang dapat di download di Google Playstore. Sistem baru monitoring hama dan penyakit ini diharapkan dapat memutus rantai pelaporan hasil monitoring sehingga penyusunan strategi pencegahan dan pengendalian dapat dilakukan secara lebih cepat dan tepat sasaran.
APLIKASI PERANGKAP LAMPU SEBAGAI SARANA MONITORING DAN PENGENDALIAN HAMA KUMBANG MALAM DI PEMBIBITAN KELAPA SAWIT
Authors: Pradana Mahardika Gama , Hartanta  , Prawiratama Hari , Eko Prasetyo Agus , Susanto Agus
Published: April 2023

Kumbang malam Apogonia sp. dan Adoretus sp. merupakan salah satu hama utama pada pembibitan kelapa sawit. Perilaku nokturnal dan fototaksis kumbang tersebut menjadi suatu pendekatan dalam menyusun perangkap lampu sebagai media monitoring yang efektif. Pada penelitian ini perangkap lampu yang digunakan terdiri dari tiga jenis warna yaitu ungu, kuning, dan putih. Hasil penelitian menunjukkan bahwa perangkap lampu dengan sumber sinar ungu mampu menarik kumbang malam Apogonia sp. dan Adoretus sp. dalam jumlah paling tinggi, diikuti dengan perangkap dengan lampu berwarna kuning dan putih. Dalam penelitian ini diperoleh informasi mengenai waktu yang menunjukkan puncak aktivitas dari kumbang malam tersebut sehingga dapat digunakan sebagai waktu acuan dalam melakukan monitoring dan pengendalian hama tersebut. Penggunaan perangkap lampu diharapkan sebagai sarana monitoring dan alternatif pengendalian yang ramah lingkungan.
PENTINGNYA BAHAN ORGANIK UNTUK MENINGKATKAN EFISIENSI DAN EFEKTIVITAS PEMUPUKAN DI PERKEBUNAN KELAPA SAWIT
Authors: Ginting Eko Noviandi
Published: April 2023

Sumber bahan organik di perkebunan kelapa sawit cukup besar, utamanya TKS dan POME yang merupakan produk samping dari pengolahan TBS di pabrik kelapa sawit. Sayangnya sejauh ini perhatian pekebun kelapa sawit terhadap pemanfaatan bahan organik di perkebunan kelapa sawit hanya dititik beratkan pada pengaruh langsung bahan organik terhadap pertumbuhan dan produksi tanaman yaitu terhadap kandungan hara yang ada pada bahan organik tersebut. Padahal, bahan organik memiliki peranan yang lebih penting dari hanya sekedar sebagai sumber hara, yaitu peranannya terhadap perbaikan kualitas tanah agar tanah memiliki kapasitas yang tinggi untuk menyediakan hara bagi tanaman sehingga dapat meningkatkan efisiensi dan efektivitas pemupukan. Telah banyak hasil penelitian yang mengungkapkan bahwa bahan organik dapat memperbaiki efisiensi dan efektivitas pemupukan melalui perannya dalam hal memperbaiki kualitas tanah. Dalam tulisan ini di uraikan secara ringkas bagaimana mekanisme bahan organik dalam meningkatkan efisiensi dan efektivitas pemupukan. Dari sifat fisik kimia misalnya, bahan organik berperan dalam memperbaiki struktur tanah sehingga tanah sebagai media tumbuh memberikan kondisi aerasi perakaran yang baik untuk mendukung perkembangan akar tanaman. Dari sifat kimia tanah, bahan organik berperan untuk meningkatkan KTK tanah sehingga hara yang dipalikasikan lewat pupuk tidak segera hilang tercuci dan dapat diserap oleh akar tanaman. Sementara itu dari sifat biologi tanah, bahan organik merupakan sumber energi bagi biota tanah untuk melakukan berbagai aktivitasnya di dalam tanah, disamping sebagai penghasil enzim, hormon, dan senyawa-senyawa organik yang mempengaruhi dinamika dan ketersediaan hara di dalam tanah.
Novos rumos da epistemologia social
Authors: Ruivo Leonardo , Cichosk Luiz , R. G. Santos Breno
Published: April 2023

O presente volume é um resultado complementar da IX Conferência de Epistemologia Social, realizada virtualmente ao longo do mês de Novembro de 2021, e visa dar continuidade aos esforços de desenvolvimento e consolidação da área de Epistemologia Social no Brasil. É particularmente importante ampliar e democratizar esse debate, posto que temas centrais da área têm, com frequência, fundamentado debates públicos sobre questões de interesse comum, seja na esfera social ou na esfera política. Temas como fake news, pós-verdade, bolhas epistêmicas, câmaras de eco, lugar de fala, epistemicídio, conversação etc., têm demandado um olhar epistemológico mais dedicado, e a Epistemologia Social possui ferramentas para lidar de modo mais especificamente filosófico com tais questões. Aqui temos um resultado direto desse esforço e traz contribuições de grande importância para a área, com trabalhos de pesquisadores e pesquisadoras que compuseram os painéis da IX CES e também outros trabalhos de pesquisadores e pesquisadoras que despontam no cenário filosófico brasileiro com contribuições relevantes para as tarefas urgentes e necessárias da Epistemologia Social.
Observation of single photon interference and Hong-Ou-Mandel dip
Authors: P Munkhbaatar , Ts Baatarchuluun , D Ulam-Orgikh , J Davaasambuu , K Myung-Whun
Published: April 2023

We have built a cost effective Hong-Ou-Mandel (HOM) interferometer by using a conventional cheap multimode laser and a home-made coincidence counting circuit and we have observed the single photon interference and HOM dip making us to measure the bandpass filter. We expect it could be a good model to the graduates trying a variety of quantum optics experiments.
Az egészségügyi adatok forgalomképessége
Authors: Menyhárd Attila
Published: April 2023

A jelen tanulmány az egészségügyi adatok átruházhatóságát vizsgálja az adatok jogi természetének kontextusában. Strukturális problémaként azonosítja, hogy az átruházhatóság határait az adatok kapcsán nem lehet a személy és a tulajdon szembeállítása mentén meghatározni, és annyiban kell ezt lehetővé tenni, amennyiben azt közérdek támasztja alá. Az adatok értékének allokálásáról jogpolitikai alapon kell dönteni, amelynek során az egyéni érdek és a közérdek között kell egyensúlyt találni. Újragondolást igényel az egészségügyi adatok feldolgozására vonatkozó tájékozott beleegyezés fogalma, a (feldolgozott) adatokért való felelősség. Kulcsszerepe van az etikai normáknak a helyes és a helytelen magatartások megkülönböztetésében.
How do students see the role of serious games in education?
Authors: Péter-Szabó Richárd
Published: April 2023

Grabbing and holding student attention was a big challenge even before the Covid- 19 era; however, the coronavirus and the obligatory digital education showed that new methods are needed to resolve these issues. One of them could be implementation of digital serious games. This paper presents the findings of a questionnaire about the feelings of students toward digital serious games. In all, 1755 answers were collected and analyzed and the results showed that most students do not shy away from using these kinds of video games in a classroom environment, although there are various concerns and key aspects educational professionals must consider.
The association between influenza vaccine effectiveness and egg-based manufacturing technology: A systematic review and US expert consensus
Authors: Chatterjee Archana , Ambrose Karita , Canaday David , Delair Shirley , Ezike Ngozi , Huber Victor , Jandhyala Ravi , Jhaveri Ravi , Nyquist Ann-Christine , Sporer Abigail , Varman Meera , Vivekanandan Renuga , Wojcik Radek
Published: April 2023

Influenza is associated with significant disease burden in the US.
Influenza vaccination effectiveness (VE) is low due to several factors,
including egg adaptations. Evidence for a relationship between egg-based
manufacturing and influenza VE remains largely disassociated, except for
two previous European consensuses. The aim of this study was to observe
US expert consensus on the phenomenon. Ten US influenza experts assessed
evidence for antigenic drift, egg adaptations, and manufacturing
component principles of the research question in a novel two-stage
online study design to observe proportional group awareness and
consensus, known as the Jandhyala Method. US experts agreed that all
component principles had a majority of strong or very strong supporting
evidence (52–86%), similar to European results (70-90%). They agreed
that global surveillance, WHO candidate vaccine virus selection, and
manufacturing stages involving eggs were the most likely to impact
influenza VE. There was unanimous agreement for a mechanistic basis for
reduced influenza VE due to egg-based manufacturing. There is now US and
European expert agreement for the increased risk of reduced influenza VE
resulting from egg-based manufacturing techniques. Increasing the use of
non-egg-based manufacturing that avoids egg-adaptations is a currently
available strategy that may improve influenza VE.
Model predictive control based on dead-zone time optimal compensation for PMSM
Authors: Guo Benshuai , Su Baili , Li Hongli
Published: April 2023

In this paper, a model predictive control algorithm based on dead-zone
time optimal compensation is proposed for permanent magnet synchronous
motor. First, the dead-time voltage vectors corresponding to each
candidate voltage vectors are analyzed. And a new finite control set is
obtained under the minimum dead-zone time. Based on the new control set,
the predictive controller is designed to obtain the optimal voltage
vector and its dead-time voltage vector. Then the beneficial dead-time
voltage vector is judged, and the dead-zone time is optimized. The
optimal dead-zone time and the optimal voltage vector are used to
achieve speed stability and good performance. Finally, a simulation
example is established to verify the feasibility and effectiveness of
the proposed algorithm.
Neo-functionalization of lineage-specific cement protein paralogs underpin the evolution of barnacle bioadhesives in larval and adult life stages
Authors: Wong Yue Him , Dreyer Niklas , Liu HaoCheng , Lan Yi , Chen Jie , Sun Jin , Zhang Weipeng , Qian Pei-Yuan , Chan Benny
Published: April 2023

Acquisition of new genes often results in the emergence of novel
functions and is a key step in lineage-specific adaptation. As the only
group of sessile crustaceans, barnacles establish permanent attachment
through initial cement secretion at the larval phase followed by
continuous cement secretion in juveniles and adults. However, the
origins and evolution of barnacle larval and adult cement proteins
remain poorly understood. By performing microdissection of larval cement
glands, transcriptome and shotgun proteomics and immunohistochemistry
validation, we identified 30 larval and 27 adult cement proteins of the
epibiotic turtle barnacle Chelonibia testudinaria, of which the majority
are stage- and barnacle-specific. While only two proteins, SIPC and
CP100K, were expressed in both larvae and adults, detection of protease
inhibitors and the cross-linking enzyme lysyl oxidase paralogs in larvae
and adult cement suggested functional convergence. Other barnacle
specific cement proteins such as CP100k and CP52k likely share a common
origin dating back at least to the divergent of Rhizocephala and
Thoracica. Different CP52k paralogs could be detected in larval and
adult cement, suggesting stage-specific cement proteins may arise from
duplication followed by changes in expression timing of the duplicates.
Interestingly, the biochemical properties of larval- and adult-specific
CP52k paralogs exhibited remarkable differences, reflecting the
composition of cement in different life stages of turtle barnacle might
be chemically different. We conclude that de novo gene formation and
duplicate neofunctionalization are pivotal to the evolution of
lineage-specific cement toolkits in barnacles, which may explain how
barnacles can inhabit diverse marine substrata.
Substitution spectra of SARS-CoV-2 genome reveals insights into the evolution of variants across the pandemic
Authors: Ashraf Javaria , Bukhari Ali Raza , Kanji Akbar , Iqbal Tulaib , Khan Waqasuddin , Hasan Zahra
Published: April 2023

Background: Changing morbidity and mortality from COVID-19 has
been associated with the emergence of new SARS-CoV-2 variants. Whereby,
acquisition of mutations in the Spike glycoprotein enhanced host
receptor binding, cell entry and antibody escape. Understanding these
can help predict the impact of these changes. We used genome sequence
data to investigate mutation rates and entropy of SARS-CoV-2 during
pandemic surges between 2020 and 2022. Methods: 1,637
SARS-CoV-2 genomes from Pakistan were analyzed using the Augur
phylogenetic pipeline. Substitution rates and entropy of genomes were
calculated year wise and, entropy in the Spike gene was compared for
2020, 2021 and 2022 (defined as periods A, B and C). Central
Findings: In period A, G clades were predominant and SARS-CoV-2 genome
substitution rate was 6.06 x 10 per site per year.
In period B, Delta variant were dominant and substitution rates
increased to 9.74 x 10 . In period C, Omicron
variants dominated with substitution rates at 5.02 x 10
. The rate of genome-wide entropy was the highest
during B particularly, in the Spike gene such as, E484K and K417N.
During C, genome-wide mutations were increased whilst entropy was
reduced. Conclusions: The highest SARS-CoV-2 genome
substitution rates in 2021 were associated with the Delta wave, which
had the greatest morbidity and mortality. These stabilized during the
Omicron wave in 2022, when COVID-19 numbers were high mortality was
lower. Assessment of SARS-CoV-2 evolution should be monitored together
with phylogeographical analysis can help predict future outbreaks and
guide public health interventions.
Talking different languages: The role of plant–plant communication when an invader beats up a strange neighborhood
Authors: Ninkovic Velemir , Hall Rea Maria , Markovic Dimitrije , Kaul Hans-Peter , Wagentristl Helmut , Urban Bernhard , Durec Nora , Renner-Martin Katharina
Published: April 2023

Chemical interaction through airborne volatile organic compounds (VOCs)
and root exudates plays a vital role in the mutualistic interactions
between plants. In response to these chemical cues, a single plant can
exhibit a multitude of adaption responses. Nowadays, one of the most
troublesome invasive alien species (IAS) in agriculture is common
ragweed ( Ambrosia artemesiifolia L.), which causes severe yield
losses in various crops. Given that little is known about how chemical
cues of this invader contribute to its invasiveness, we investigated the
effects of airborne VOCs and root exudates released by common ragweed on
growth and allocation patterns of wheat, soybean and maize, and the
effects of these crops on common ragweed. Exposure to VOCs released by
ragweed induced a significant reduction in the aboveground dry mass of
soybean and wheat, whereas maize showed no changes in its biomass
production. In contrast, ragweed itself was completely unaffected when
exposed to crops or a conspecific. We observed significant changes in
plant traits, such as lower biomass production, lower specific leaf area
or higher chlorophyll contents after exposure to VOCs of ragweed, all of
which can be linked to an increase in stress. Root choice test showed
that all crops and ragweed significantly avoided root exudates of common
ragweed, indicating that the root exudates as belowground cues play a
vital role in ragweed and crop chemical interactions. The present study
shows that the plant response to either above or below ground chemical
cues is highly dependent not only on the presence but also on the
identity of the neighbor pointing out the complexity of plant–plant
communication.
Turning lakes into river gauges using the LakeFlow algorithm
Authors: Riggs Ryan M , Allen George Henry , Brinkerhoff Craig B , Sikder Md. Safat , Wang Jida
Published: April 2023

Rivers and lakes are intrinsically connected waterbodies yet they are
rarely used to hydrologically constrain one another with remote sensing.
Here we begin to bridge the gap between river and lake hydrology with
the introduction of the LakeFlow algorithm. LakeFlow uses river-lake
mass conservation and observations from the Surface Water and Ocean
Topography (SWOT) satellite to provide river discharge estimates of lake
and reservoir inflows and outflows. We test LakeFlow performance at
three lakes using a synthetic SWOT dataset containing the maximum
measurement errors defined by the mission science requirements, and we
include modeled lateral inflow and lake evaporation data to further
constrain the mass balance. We find that LakeFlow produces promising
discharge estimates (median Nash-Sutcliffe efficiency=0.88, relative
bias=14%). LakeFlow can inform water resources management by providing
global lake inflow and outflow estimates, highlighting a path for
recognizing rivers and lakes as an interconnected system.
A characterization of 4-χρ-(vertex-)critical graphs
Authors: Ferme Jasmina
Published: April 2023

Given a graph G, a function c : V(G) ?{1,..., k} with the property that
for every u?v, c(u) = c(v) = i implies that the distance between u and v
is greater than i, is called a k-packing coloring of G. The smallest integer
k for which there exists a k-packing coloring of G is called the packing
chromatic number of G, and is denoted by ??(G). Packing chromatic
vertex-critical graphs are the graphs G for which ??(G ? x) < ??(G) holds
for every vertex x of G. A graph G is called a packing chromatic critical
graph if for every proper subgraph H of G, ??(H) < ??(G). Both of the
mentioned variations of critical graphs with respect to the packing
chromatic number have already been studied [6, 23]. All packing chromatic
(vertex-)critical graphs G with ??(G) = 3 were characterized, while there
were known only partial results for graphs G with ??(G) = 4. In this paper,
we provide characterizations of all packing chromatic vertex-critical graphs
G with ??(G) = 4 and all packing chromatic critical graphs G with ??(G) = 4.
Bivariate Bernstein-Kantorovich operators with a summability method and related GBS operators
Authors: Ansari Khursheed , Karakılıç Sedef , Özger Faruk
Published: April 2023

In this paper, we apply four-dimensional infinite matrices to newly
constructed original extension of bivariate Bernstein-Kantorovich type
operators based on multiple shape parameters. We also use B?gel continuity
to construct the GBS (Generalized Boolean Sum) operators for defined
bivariate Kantorovich type. Moreover, we demonstrate certain illustrative
graphs to show the applicability and validity of proposed operators.
Simulation Game-Based Governance System Education
Authors: Putra Glenn Hariyanto , Nugroho Erdhi Widyarto , Chandrawati T.Brenda
Published: April 2023

Democratization is a process of people's participation in the country's political activities, but this process is quite difficult because the public's perception of the government tends to be negative. One way to increase public awareness about government is to use educational games such as "Governman" which teach about the government system through simulation and make players think critically and creatively. The game "Governman" is made using the waterfall method and has gone through all the stages in that method. Research has been conducted to show that this game is effective in encouraging the player's intention to learn about the government system. It is hoped that this game will be an interesting and easy-to-understand way for players to learn about the government system. Research has been conducted to evaluate the effectiveness of this game and the results show that this game has a valid correlation between Performance Expectancy, Effort Expectancy, Hedonic Motivation and Behavioral Intention. This shows that this game is effective in encouraging players' intentions to learn and understand the government system
Ecommerce Website Development for Melisa Baby and Kids Shop
Authors: Ardianto Elizabeth Kurniawan , Sanjaya Ridwan , Harnadi Bernardinus
Published: April 2023

In the current era of technological development, someone is always demanded to be creative and innovative in their existence in the digital world. The strategies to jump into the digital marketing field are an effective way to market products in an era of an onslaught of technological advances and the addition of the post-COVID-19 pandemic. A part of digital marketing, internet marketing is one form of marketing innovation that utilizes internet technology and creates marketing in the digital world, including among others, social media marketing, content marketing, and online platform marketing [1]. The baby shop business is one of the businesses that can implement digital marketing because the needs of babies are a primary need that must be sufficient. Strategies that can be used to increase sales of baby and children's equipment businesses are developing an ecommerce website that implements plugins, attractive landing page designs, promotion through social media, integration of online transactions, payments, and logistics, and creating a user-friendly website. Implementation of an e-commerce website can increase revenue and facilitate product marketing. This research aims to increase Melisa Baby and Kids Shop sales through ecommerce website creation strategies by utilizing plugins that enhance website functionality. By implementing those strategies, the result to business is gaining more visibility and increased sales by up to 30% based on an interview with owner.
Relationship between mother's oral health literacy level with oral hygiene behavior and self-reported oral health status in sociodemographic scope
Authors: Maudi Tiarani , Suryanti Netty , Setiawan Asty Samiaty
Published: April 2023

ABSTRACTIntroduction: Oral Health Literacy (OHL) plays an important role in reducing the gap in promoting oral health. Oral health literacy of mothers is important due to maternal OHL can affect the family's oral health, especially in children. Sufficient OHL of mothers also help strengthen their capacities to improve their own and their children's oral health. The purpose of this study was to analyze the oral health literacy level of mothers and its relationship to the oral hygiene behavior and self-reported oral health status in the sociodemographic scope. Methods: The type of research was correlational analytics with cross-sectional techniques. The samples were 158 mothers, collected using purposive sampling in Parigi District, Pangandaran Regency. Data were collected using the Health Literacy in Dentistry (HeLD-14) questionnaires which had been cross-adapted and included questions to assess oral hygiene behaviors with the Indonesian version of the oral hygiene behavior index. Data were analyzed using the Pearson correlation test and independent sample t-test. Results: The majority of mothers had a good educational level and did not get employment, and had a good level of oral health literacy, with an average score of 49.63±7.16. Dental hygiene behaviors were in the good category with a mean score of 3.13±0.82 and the results of self-assessment mostly stated that the oral and dental conditions were in a proper state. The results of the OHL correlation tests with oral hygiene behaviors and self-reported oral health status showed significant relations with low correlations (p=0.04; r=0.16) and (p=0.01; r=0.21). Conclusion: Mothers’ oral health literacy level is in good category and there are relations between oral dental health literacy with oral hygiene behaviors and self-reported oral health status.Keywords: oral health literacy, HeLD-14, oral hygiene behavior, sociodemographic, mother, oral health status
Yhdessä kohti sujuvaa hybridityöskentelyä ja digitaalisia järjestelmiä: STKS:n toiminta vuonna 2022
Authors: Lehto Anne , Luokkanen Sinikka
Published: April 2023

Vuosi 2022 oli STKS:n toiminnassa muutosten ja yllätysten aikaa: Puheenjohtaja, jäsenlehden Signumin päätoimittaja ja taloudenhoitaja vaihtuivat. Luotiin uusi strategia, Signum siirrettiin verkkoon ja otettiin käyttöön uutiskirje. Seura toimintatapa muuttui hybridityöskentelyksi ja sen mukaisesti järjestettiin kaksi webinaaria tai etätyöpajaa. Jatkossa seura panostaa kouluttamiseen ja alan sisäiseen keskusteluun, tervetuloa mukaan!
Kirjastotyön muutokset ja haasteet mietityttävät – esittelyssä STKS:n hallituksen uudet jäsenet
Authors: Toimitus Signum
Published: April 2023

Suomen tieteellisen kirjastoseuran hallituksessa aloitti vuoden 2022 alussa neljä uutta jäsentä: Tuija Korhonen (Helsingin yliopiston kirjasto ), Marjo Kuusela (Helsingin yliopiston kirjasto), Jaana Latvanen (Seinäjoen ammattikorkeakoulun kirjasto) ja Henri Pitkänen (Suomen ympäristökeskus, Avoin tiede). Tässä haastattelussa hallituksen uudet kasvot kertovat lyhyesti aja­tuksiaan kirjastotyöstä ja siitä, kuinka haluaisivat vaikuttaa stks:n toimintaan.
Palveluympäristö muuttuu, asiakkaat pysyvät: STKS:n asiakaspalvelutyöryhmän esittely
Authors: Kultanen Virpi , Leppänen Tytti
Published: April 2023

STKS:n asiakaspalvelutyöryh­mä on aktiivinen porukka, jossa on maantieteellisesti laaja edustus erilaisista kirjastoista. Työryhmässämme on avoin, keskusteleva ja rento tekemisen meininki! Ennen koronaa järjestimme joka syksy Helsingin kirjamessuviikolla jo jonkinlaiseksi brändiksi muodostuneen asiakaspalveluaiheisen seminaarin Tieteiden talolla. Tänä vuonna pääsemme toivottavasti jatkamaan liveseminaariperinnettämme – merkatkaahan siis jo kalentereihinne torstai 26. 10. 2023!
Aineistot avoimiksi yhteiskuntatieteissä – mutta mistä käyttäjät?
Authors: Late Elina
Published: April 2023

Yhteiskuntatieteellisillä aloilla on pitkät perinteet aineistojen uudelleen käytölle tutkimuksessa. Esimerkiksi Maailmanpankin ja oecd:n tarjoamia tilastoaineistoja on hyödynnetty vuosikymmeniä tutkimuksessa. Tutkimuksen digitalisoituminen ja vaatimus tieteen avoimuudesta ovat mahdollistaneet aineistojen jakamisen organisaatioiden ohella myös yksittäisille tutkijoille. Tänä päivänä tutkijoiden tallentamien aineistojen voisi olettaa muodostavan valtaosan tutkimusdatojen säilyttämiseen ja jakamiseen erikoistuneiden arkistojen sisällöstä