bluuebunny/crossref_metadata_2025 huggingface dataset:
RETROSPECTIVE ANALYSIS OF BIOCHEMICAL AND HAEMATOLOGICAL PARAMETERS IN COVID-19 PATIENTS ADMITTED TOINTENSIVE CARE UNIT (ICU) IN A TERTIARY CARE HOSPITAL IN MIZORAM, INDIA
Authors: L.Vangchhia Belinda , Hnamte Sairengpuii , K. Chaudhary Jitendra , Zothanzauva J.C , Hrahsel Lalrinawmi , a Lalremruati , Koch Nirensingh
Published: April 2024

Background:This study aims to assess the effects and significance of both biochemical and haematological parameters on COVID-19 patients admitted to the intensive care unit (ICU) during the peak second wave of the infection (May to August 2021) in a designated COVID-19 hospital in Mizoram, India. Methods:All existing data on COVID-19 patients admitted during the period of May to August, 2021 was collected from Medical Record department of Zoram Medical College/ State Referral Hospital (ZMC/ SRHF), Falkawn, Mizoram. Results:Out of one hundred eighty-seven (N = 187) COVID-19 positive ICU patients admitted to Zoram Medical College/ State Referral Hospital (ZMC/ SRHF),Falkawn from May to August, 2021, 111 (59.4%) were males and 76 (40.6%) were females of which 125 (66.8%) patients died while 62 (33.2%) survived. Mortality rate was comparatively higher in male patients (41.7%) than in female patients (25.1%). Majority of patients belonged to the elderly aged group (65 years and above) with 70 (37.4%) cases and no patients belonging to children age group (below 18 years) were admitted to ICU. Statistical significance was observed in haematological parameters like total RBC and WBC (monocytes, polymorph/neutrophils, leucocytes) count, platelet count, erythrocyte sedimentation rate (ESR), neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR). In addition, clear significance was also noted in immunological parameters like C-reactive protein (CRP), blood glucose and biochemical parameters like serum creatinine, blood urea and aspartate amino transferase (AST). Conclusion:Our findings suggest the vitality of closely monitoring biochemical parameters like kidney and liver function tests (blood urea, serum creatinine, potassium, bilirubin, albumin, direct and indirect conjugated bilirubin, SGOT/ AST), CRP and haematological tests like total RBC, WBC, platelet counts, ESR, NLR and PLR to enhance immediate clinical interventions. Prognosis of these parameters and prompt treatment can potentially aid in further delay towards the onset of several other severe symptoms and may lead to eventual cure.
CONTROVERSIAL REVIEW OF SHANKHAPUSHPI (CONVOLVULUS PLURICAULIS CHOIS.)AND ITS CONSERVATION W.S.R. TO CONSERVATION AND PROPAGATION OF MEDICINAL PLANTS
Authors:   Assistant Professor Department of Dravyaguana., Kirte Komal
Published: April 2024

Shankhapushpi (Convolvulus pluricaulis Chois.) quoted best Medhya Rrasayana in Ayurveda samhitas. It is perennial herb belongs to Convolvulaceae family. All parts of the Shankhapuspi are known to possess therapeutic benefits. The plant is used locally in India and Chinese medicine to cure various diseases. It is also one of a most important controversial drug mentioned in Ayurveda. Material and methods-information on the Shankhapushpi (Convolvulus pluricaulis Chois.) was collected from Ayurvedic samhitas and textbooks. It was also collected via electronic search (using Pub Med, Sci-Finder, Google scholar and Web of science) and library search for Articles published in peer reviewed journals.
BEYOND THE GENES: UNVEILING THE POWER OF METABOLOME INTERACTIONS FOR BIOMEDICAL PROGRESS
Authors:   Centre for Genomics and Proteomics, Department of Biotechnology, KoneruLakshmaiah EducationFoundation, Guntur, Andhra Pradesh, India., Mulpuri Sindhu , Singh Aditi ,   Centre for Genomics and Proteomics, Department of Biotechnology, KoneruLakshmaiah EducationFoundation, Guntur, Andhra Pradesh, India., Veeranki Yeseswini ,   Centre for Genomics and Proteomics, Department of Biotechnology, KoneruLakshmaiah EducationFoundation, Guntur, Andhra Pradesh, India., Bhavani Venkatesh Pasupuleti Sai ,   Centre for Genomics and Proteomics, Department of Biotechnology, KoneruLakshmaiah EducationFoundation, Guntur, Andhra Pradesh, India., Shaik Salma ,   Centre for Genomics and Proteomics, Department of Biotechnology, KoneruLakshmaiah EducationFoundation, Guntur, Andhra Pradesh, India., Chalasani Rithvik ,   Centre for Genomics and Proteomics, Department of Biotechnology, KoneruLakshmaiah EducationFoundation, Guntur, Andhra Pradesh, India., Kothapalli Bhargav ,   Department of Biotechnology, Andhra Loyola College, Vijayawada, Andhra Pradesh, India., Priya Amarthaluri Santhi ,   Department of Biotechnology, Sri Venkateshwara College of Pharmacy, Madhapur, Hyderabad, Telangana, India.
Published: April 2024

The human metabolome, the complete set of small molecules within a cell, tissue, or organism, plays a critical role in health and disease. Understanding the complex interactions within the metabolome holds immense potential for advancements in biomedicine. This study explores into recent research efforts focused on unraveling these interactions and their impact on human health.The realm of metabolic regulations encompasses the diverse and extensive network of metabolic pathways within the human body. These pathways collectively drive various physiological and biological processes towards proper functionality. Amidst the challenges posed by diseases, the creation of new metabolic pathways exemplifies the promise of metabolic engineering in therapeutic interventions. Exploring metabolic functions in the human body can be facilitated by simulated yeast models, offering insight into the intricate interactions among molecular metabolomes.
A RARE CASE OF OVARIAN AGENESIS AND HYPOPLASTIC UTERUS IN A PREPUBERTALGIRL WITH NORMAL 46, XX KARYOTYPE
Authors:   Department of Endocrinology, Diabetology, Metabolic Diseases and Nutrition, Mohammed VI University Hospital of Marrakesh, Morocco., Ismail Zahra , Bifoume Ndong Charlene-Ludwine ,   Department of Endocrinology, Diabetology, Metabolic Diseases and Nutrition, Mohammed VI University Hospital of Marrakesh, Morocco., Rafi Sana ,   Department of Endocrinology, Diabetology, Metabolic Diseases and Nutrition, Mohammed VI University Hospital of Marrakesh, Morocco., El Mghari Ghizlane ,   Department of Endocrinology, Diabetology, Metabolic Diseases and Nutrition, Mohammed VI University Hospital of Marrakesh, Morocco., El Ansari Nawal ,   Department of Endocrinology, Diabetology, Metabolic Diseases and Nutrition, Mohammed VI University Hospital of Marrakesh, Morocco.
Published: April 2024

Delayed onset of puberty and primary amenorrhea pose diagnostic challenges, often associated with diverse etiologies including hypothalamic-pituitary disorders, gonadal dysgenesis, and mÃ¼llerian duct malformations.Historically, such syndromes have been associated with XY chromosomal components, but rare cases in karyotypically normal females (46, XX) have been reported. Comparisons with similar cases, including atypical forms of Mayer-Rokitansky-KÃ¼ster-Hauser (MRKH) syndromeare made, highlighting the rarity of this condition. Despite advancements, the genetic basis remains unspecified, underscoring the need for further research. We present a unique case of gonadal agenesis and hypoplastic uterus in a 46,XX individual, without associated organ system anomalies, contributing to primary amenorrhea. Diagnostic evaluations including hormonal assessment, and pelvic MRI confirmed the absence of ovaries and severe hypoplasia of paramesonephric duct (PMND) derivatives. Treatment with 17beta estradiol successfully induced puberty, highlighting the clinical importance of timely intervention. Early detection of such cases is crucial for providing comprehensive support and improving patient outcomes.
ALTERATIONS IN THE NUCLEIC ACID AND PROTEIN CONTENT IN SORGHUM BICOLOR PLANTS UNDER ZINC EXCESS
Authors:   Associate Professor, St. Anns College for Women, Mehdipatnam, Hyderabad - 28, Telangana State, India., Usha Shri P.
Published: April 2024

Trace metals like zinc are natural components of the environment but, elevated and potentially toxic levels sometimes occur. The use of zinc fertilizers and pesticides is a common agricultural practice, which over the years lead to elevated levels of zinc in the soil.In the present investigation seven-day old Sorghum bicolor plants were treated with five different concentrations of zinc solution and sampling was done at different stages of plant growth to estimate the nucleic acid and protein content. The results revealed a significant reduction in DNA, RNA and proteins in the plants growing at higher concentrations of zinc treatment as compared to control. Toxic levels of heavy metal ions induce several cellular stress responses and damages different cellular components such as membranes, proteins and DNA.
ENDOSCOPIC TRANSANAL REMOVAL OF EGG FROM RECTOSIGMOIDAL JUNCTION
Authors:   ESI Medical College and Research Centre., Mikkilineni MBBS Jahnavi , Nimmagadda MBBS Rithish ,   Kamineni Academy of Medical Sciences and Research Centre, Hyderabad., Pudhota Amshu ,   Gastroenterology Specialist at Baylor Scott & White - Mansfield, Texas., G. Pudhota MD Sunitha ,   Gastroenterology Specialist at Baylor Scott & White - Mansfield, Texas.
Published: April 2024

It is not uncommon that we encounter patients with different kinds of foreign bodies in the rectumfor a variety of reasons. Most of the cases reported in the literature reveal that rectal foreign body insertion is mainly for sexual gratification. To avoid the embarrassment and scrutiny, patients often delay seeking medical help which complicatesmedical management. We discuss a case of a 21-year-old male who presented after voluntary insertion of multiple eggs into the anus. Although the suggested protocol and technique was followed to retrieve the egg and the debris, it still required some creativity and careful methodology.
AN AYURVEDIC METHODOLOGY FOR MANAGING DIABETIC DYSLIPIDEMIA - A CASE REPORT
Authors:   Assistant Professor, Department of Kayachikitsa, Patanjali Bhartiya Ayurvigyan Evum Anusandhan Sansthan, Haridwar., Kumar Srivastava Avinash , Painuly Paridhi ,   Post Graduate Scholar, Department of Kayachikitsa, Patanjali Bhartiya Ayurvigyan Evum Anusandhan Sansthan, Haridwar., a Vandana ,   Post Graduate Scholar, Department of Kayachikitsa, Patanjali Bhartiya Ayurvigyan Evum Anusandhan Sansthan, Haridwar., Negi Mudita ,   Post Graduate Scholar, Department of Kayachikitsa, Patanjali Bhartiya Ayurvigyan Evum Anusandhan Sansthan, Haridwar.
Published: April 2024

Diabetic dyslipidemia is characterized by elevated plasma triglyceride levels, decreased HDL cholesterol levels, and an increase in small dense LDL-cholesterol particles. These lipid alterations in diabetes are linked to heightened free fatty acid flux due to insulin resistance. With the availability of various lipid-lowering medications and supplements, patients now have more options to reach target lipid levels. Lipid-lowering therapies in modern medicine, such as statins and fibrates, are generally well-tolerated with minimal side effects. However, these treatments often necessitate lifelong usage, which can impose significant financial strain, particularly in developing countries like India.In Ayurveda, dyslipidemia is understood as the manifestation of an imbalance in the Medovahasrotas.Dyslipidemia manifests as the consequent output of Medovahasrotodushti. A 31-year-old male patient presented with complaints of pain in calf muscles and weight gain. Upon investigation, his total cholesterol level was found to be elevated at 211 mg/dl, and triglycerides were elevated to 683.80 mg/dl. Giloykwath along with arjunkwath, Madhunashinivati extra power, Tablet lipidom, and Tablet Madhugrit were administered for the shaman therapy. Upon completion of the treatment, significant improvements were observed in the patients complaints. Additionally, a significant improvement was noted in the Lipid Profile.
Bacillus anthracis infection in humans and animals
Authors: CZEKAJ ZUZANNA , KLIMOWICZ-BODYS MAŁGORZATA D. , KANIAK RAFAŁ , FLOREK MAGDALENA , RYPUŁA KRZYSZTOF
Published: April 2024

Bacillus anthracis is the zoonotic agent that causes the disease known as anthrax. This pathogen has always been high on the list of potential agents with respect to biological warfare and bioweapons. B. anthracis causes severe respiratory, and cutaneous as well as gastrointestinal infections in humans. Among animals, the group most susceptible to infection are ruminants, in which the most common route of infection is local damage to the mucous membrane of the oral cavity and/or gastrointestinal tract, less often the development of a widespread disease as a result of inhalation of spores. This review describes various features associated with pathogenicity-related factors of B. anthracis, pathogenesis of anthrax, human and animal forms of the disease, and the possibility of preventing and treating the disease. The article also mentions the potential use of the bacteria for bioterrorism as a biological weapon.
USE OF SPECIAL KNOWLEDGE DURING THE PRE-COURT INVESTIGATION OF FRAUDS, COMMITTED THROUGH THE INTERNET NETWORK
Authors: Grynko Larysa P.
Published: April 2024

In article emphasizes that one of the necessary conditions for the effective investigation of fraud committed through the Internet, need to use special knowledge. Emphasizing that the effectiveness of the disclosure and investigation of fraud committed through the Internet depends, first of all, on the application of a comprehensive approach, which is manifested in the combination of various forms of the use of special knowledge at various stages of criminal proceedings. It was emphasized that the main forms of using special knowledge in the investigation of the analyzed fraud are obtaining consultations from specialists on issues that require special knowledge; the participation of specialists in conducting investigative (search) actions; conducting forensic examinations. The process of uncovering and investigating fraud committed through the Internet is accompanied by the leading role of a specialist in this field, consists in the examination of computer equipment, digital electronic media, mobile phones, processing of work records of computer equipment users, etc. Examine of computer information carriers will make it possible to reliably assert the presence of material traces of fraud (computer, electronic, digital), its professional removal, any damage or destruction of existing information is impossible. Since the mechanism of committing fraudulent actions is related with electronic media that display information about the crime, and the implementation of a number of operations that take place through electronic and telecommunication networks, most often prescribed the following categories of cases : a) computer and technical examination; b) telecommunications; c) commodity expert; d) judicial and commercial and others.
MOTIVE AND PURPOSE AS A COMPONENT OF THE CRIMINALISTICS CHARACTERISTICS OF TERRORISM (CRIMINALISTICS AND PSYCHOLOGICAL ASPECTS OF FORMATION)
Authors: Chornyi Hennadii O.
Published: April 2024

The work is devoted to the study of the problems of forming a criminalistics characteristic of terrorism, its structure and content. The author examines the genesis of the concept of "forensic characteristic", its structure, content and the corresponding correlation between its elements. Taking into account the following main elements of the criminalistics characterization of terrorism: method of crime (which includes the method of preparation, method of commission and method of concealment of crime); object of criminal offence; place, time and setting of crime (conditions of crime); tools and means of crime; identity of the offender; identity of the victim (victim), the author proposes to include such an element as the purpose and motive of terrorism. From the point of view of the idea of the scientific work, the inclusion of such an element as "purpose and motive for committing terrorism" in the structure of the criminalistics characteristic is due to the fact that the purpose and motive are the main identifying features of this type of crime, which has a material composition in accordance with the disposition of Article 258 of the Criminal Code of Ukraine and the Law of Ukraine "On Combating Terrorism". The author examines the psychological component of the concepts of "purpose" and "motive" of committing terrorism and provides an extended interpretation of these concepts. Thus, the goal is seen as, on the one hand, a conscious image of the intended result, which the action is aimed at achieving. The goal is formed as a result of the awareness of motives, when it becomes clear what exactly will satisfy the need. A goal is formed when the direct realisation of a motive is impossible.From another scientific point of view, a goal is a psychosocial quality that stems from a sense of initiative, thanks to which a person's ability to behave purposefully gradually increases. Further, the author argues that from the point of view of the general provisions of psychology, intentional criminal offences (which include, first of all, terrorism) are considered as a complex volitional act, which is characterised by the fact that the action (in the sense of a criminal act) is preceded by consideration of consequences, awareness of motives, decision-making, etc. Volitional acts are performed in accordance with certain motives. A motive is considered as a certain mental experience that prompts and recognises a person's choice of a certain system of actions. The article emphasises that the criminalistics characterisation of terrorism should be considered as an information model, which contains qualitative and quantitative retrospective indicators of typical features (method of commission, typical trace pattern, identity of the perpetrator, identity of the victim) inherent in terrorism, and specific features (purpose and motive of commission) that allow it to be separated from other types of crimes.
PROBLEM ASPECTS OF CONDUCT OF TAX CONTROL MEASURES
Authors: Shevchyk Oleksandr S.
Published: April 2024

The article examines and highlights the problems associated with the collection, use and study of evidence in the consideration by courts of cases on the so-called tax criminal offenses on the basis of scientific developments, analysis of current legislation and judicial practice. The author concludes that the issue of peculiarities of collection, examination and use of evidence in such a specific criminal offense as tax evasion, fees (mandatory payments) is relevant for scientific research, since it has a number of both theoretical and practical problems and gaps, which is primarily associated with the specifics of tax criminal offenses, and with the imperfection of legislation. Evidence has its own specifics and peculiarities in the investigation and prosecution of tax criminal offenses. Pre-trial investigation and trial of criminal proceedings on tax evasion are characterized by many peculiarities, which is due to the specifics of legal constructions of criminal offenses. There is ambiguity of judicial practice in this category of cases because of this. Taking into account the imperfection, inconsistency of the domestic tax, criminal and criminal procedural legislation and the insufficiently high competence of law enforcement and judicial authorities, there are frequent violations of taxpayers' rights in criminal proceedings when bringing guilty persons to justice. The author thoroughly investigates the features of the types of evidence that are most often used in the investigation and prosecution for tax offenses (testimony of witnesses, documents, expert opinions). The legal nature of the tax audit report is considered and the peculiarities of the use of the tax audit report as one of the fundamental evidence in criminal proceedings on tax criminal offenses are studied. The illegality of appointment of tax audit within the framework of criminal proceedings has been substantiated.
PREPARATION AND APPLICATION PROPERTIES OF Ti-Si GLYCOL SALT CATALYSTS FOR POLYESTERS
Authors: Yu Yang , Shen Guoliang , Xu Tie jun , Wen Ruiyang , Wang Yong jie , Huo Yue , Xu Shi jie
Published: April 2024

Silicon catalysts have very low catalytic activity in polyester (PET). However, titanium catalysts have high catalytic activity in polyester. The simultaneous use of titanium and silicon catalysts is effective in reducing the activity of a single titanium catalytic base agent. In addition, the glycol salts of titanium and silicon (Ti-EG and Si-EG) prepared in the present invention for use in the polyester catalytic process can avoid the introduction of other groups of impurities during the polyester catalytic process, which would lead to premature capping of the polyester in the process of polycondensation and chain building and make it difficult to increase the molecular weight, and thus affect the quality of the polyester. It has been verified that the ratio of Ti:Si is 1:1 (mol), and total amount added to the catalyst is 0.15% of the raw material amount, and the polycondensation temperature was 260-280 °C for 60 min. Compared with the single Ti-EG catalyst, the b* value of the synthesized PET was significantly reduced, and the molecular weight and other indexes did not change too much. In addition, at the end of catalysis, the catalyst was uniformly dispersed in the reaction system, which could be used as a matting agent for PET.
Fortifying Dairy Products with Vitamin A Nano-Emulsion
Authors: Blinov Andrey , Gvozdenko Alexey , Golik Alexey , Kolodkin Maxim , Filippov Dionis
Published: April 2024

Vitamin A deficiency can be compensated by fortifying socially essential foods with its nano-emulsion. This research featured the effect of vitamin A nanoemulsion on the physicochemical parameters of pasteurized milk with a fat content of 3.2 %. To synthesize the vitamin A nano-emulsion, vitamin A was mixed with Tween 80 as a solubilizer. The dynamic light scattering method showed that the average hydrodynamic radius of vitamin A micelles was 62 ±13 nm. In this study, vitamin A nano-emulsion had no significant effect on such physicochemical properties of milk as titratable acidity, radius of protein and fat fractions, and ζ-potential and electrical conductivity. The additive demonstrated good prospects as a source of vitamin A to be used in the dairy industry.
Improving Lactose Crystallization in Milk Sugar Production
Authors: Shokhalov Vladimir , Gnezdilov Anna , Shokhalova Veronika
Published: April 2024

This article introduces a new milk sugar technology with improved purification and lactose crystallization. The technology consisted of ultrafiltration of skim milk, nanofiltration of UV-permeate, electrodialysis, condensing, lactose crystallization, and drying. Nanofiltration followed by electrodialysis provided 70–90 % desalting. After condensing to 53–55 % solids, the resulting syrup was heated to 75 °C. The lactose crystallization included two stages. During the first stage, the syrup was cooled by 4–5 °C per 1 min until it dropped down to 27–33 °C, i.e., the temperature of enhanced lactose crystallization. At that moment, 0.01–0.02 % fine crystalline lactose entered the syrup. At the second stage, the crystallized substance continued to cool down at a rate of 1–2 °C per 1 min until the temperature was 10–15 °C. To complete the process, the crystalline lactose remained at this temperature for 5–10 min. The finished product was subjected to granulometric microscopy to determine the homogeneity coefficient. The homogeneity of crystals increased, which means that the quality of the finished product improved. The cooling method was tested on the premises of the Scientific and Experimental Dairy Plant, N. V. Vereshchagin Vologda State Dairy Academy.
Estimation of instantaneous peak flows in Canadian rivers: an evaluation of conventional, nonlinear regression, and machine learning methods
Authors: Khaliq Muhammad Naveed
Published: April 2024

Instantaneous peak flows (IPFs) are often required to derive design values for sizing various hydraulic structures, such as culverts, bridges, and small dams/levees, in addition to informing several water resources management-related activities. Compared to mean daily flows (MDFs), which represent averaged flows over a period of 24 h, information on IPFs is often missing or unavailable in instrumental records. In this study, conventional methods for estimating IPFs from MDFs are evaluated and new methods based on the nonlinear regression framework and machine learning architectures are proposed and evaluated using streamflow records from all Canadian hydrometric stations with natural and regulated flow regimes. Based on a robust model selection criterion, it was found that multiple methods are suitable for estimating IPFs from MDFs, which precludes the idea of a single universal method. The performance of machine learning-based methods was also found reasonable compared to conventional and regression-based methods. To build on the strengths of individual methods, the fusion modeling concept from the machine learning area was invoked to synthesize outputs of multiple methods. The study findings are expected to be useful to the climate change adaptation community, which currently heavily relies on MDFs simulated by hydrologic models.
Effects of Compound in Hedyotis diffusa Willd against Acute Myeloid Leukemia: An In Silico and In Vitro Study
Authors: Lyu Chunyi , Yin Xuewei , Li Zonghong , Wang Teng , Xu Ruirong
Published: April 2024

Background:

Hedyotis diffusa Willd (HDW) is an herb that has been used empirically for
treating cancer, and its antileukemic effect has been confirmed by laboratory evidence. This study
aimed to explore the underlying mechanism by which HDW and its active compound exert effects on
acute myeloid leukemia (AML) through in silico analyses combined with experimental validation.

Methods:

The targets of the compounds were collected from the database and intersected with AML
targets. Based on these data, a protein-protein interaction (PPI) network and compound-target (C-T)
network were constructed, and KEGG enrichment analysis was performed. Topological analysis of
the C-T network and PPI network was performed to screen for hub compounds and targets. Molecular
dynamics simulations were conducted to test the binding mode and strength between the targets
and the compounds at the molecular level. Cell viability, flow cytometry, ELISA, and Q-PCR were
further used to evaluate the in silico results.

Results:

A total of 86 targets of 12 screened active compounds of HDW against AML were identified.
According to topological analysis, tumor protein p53 (TP53) and signal transducer and activator
of transcription 3 (STAT3) exhibited the highest degree of centrality (DC) in the PPI networks of
HDW targets. Quercetin had a higher affinity for TP53 than for STAT3. Molecular dynamics simulations
confirmed that the TP53-quercetin docked complex was stable with respect to the original
TP53-ligand complex. The targets of HDW and quercetin against AML were significantly enriched
in multiple biological processes, including the p53 signaling pathway and apoptosis. The results from
the in vitro experiment confirmed that quercetin triggers apoptosis in the human AML cell line KG-1
through the p53 pathway protein.

Conclusion:

This study outlines the multi-compound, multi-target, and multi-pathway mechanism by
which HDW affects AML based on an in silico predictive model and further validates the antileukemic
mechanism of the screened active compound in an in vitro model. This study provides a perspective
for studying the antileukemic mechanism of HDW for further research.
Revolutionizing Psychiatric Care: Unleashing the Potential of
Augmented and Virtual Reality for Diagnosis and Education
Authors: Hussain Md Sadique , Saraswat Nikita , Bahl Gurusha , Agrawal Mohit , Bisht Ajay Singh , Sharma Rahul , Kumar Rajesh
Published: April 2024

New technologies, such as augmented reality (AR), mixed reality (MR), and
virtual reality (VR), are not only of interest to gamers but are increasingly being used in
health care as well. Visual content is used in everyday life to enhance the user's visual input. Its medicinal uses have been extensively studied. It can be a promising surgical technique that requires considerable accuracy. Furthermore, the emotional engagement and
sensation of participation in the AR program impact the level of the customer experience.
These experiences may enhance the efficacy of AR in the management of psychiatric problems. This paper presents an overview of AR and reviews the latest medical applications in
diagnosing and treating psychiatric disorders. However, it is fair to say that VR systems
have easy delivery with well-controlled sensory motives. The prospect of VR systems is
that they could be a new clinical tool for patients with certain psychiatric symptoms. Besides the lack of big observational studies and cost-effectiveness research, it appears that
physicians will soon adopt this new technology.
A Systematic Literature Review on the Predictors of Drug Abuse, Substance Use, and Opioid Misuse among Adolescents
Authors: Isnain Mohd Dzulkifli , Mohamed Harith Nor Hafizah , Bakar Ahmad Naqiyuddin
Published: April 2024

Opioid misuse and dependence on prescribed opioids have strong link with drug addiction prevalence among adolescents. To gather evidence on the predictors of substance use, opioid abuse, and misuse of prescribed opioids, a systematic literature review was conducted covering articles published between 2016-2022. Of the 31 included articles, descriptively, substance use was considered as the dependent outcome in most of the studies (n = 15), compared to opioid misuse (n = 11), and prescription opioid misuse (n = 5). Resultantly, the common factors for substance use, opioid abuse, and misuse of prescribed opioids were broadly categorised into family-related factors, pain intensity and interference, comorbidity and psychopathology, demographic factors, substance use disorders and other drug addictive behaviours, and peer influence. Apart from the need to provide alternative pain management strategies, these factors should be considered by clinicians in identifying adolescents who are currently engaged in substance use or opioid abuse, and those likely to misuse prescribed opioids in the future.
Determinants of Financial Planning for Retirement: A bibliometric analysis
Authors: Han Ren , Lim Thien Sang
Published: April 2024

Many countries face the challenge of providing an adequate retirement income for their aging population. Therefore, personal retirement provision is becoming an important issue. The purpose of this study is to conduct a systematic review of existing research on the determinants of financial planning for retirement (FPR). Using bibliometric analysis, 107 studies were included to examine the most recent trend. The results suggest that concepts such as income and psychology are issues that require further investigation. The findings shed light for future study so that more studies can be done in countries with different cultures to gain deeper insights.
Reforming Model of University Leadership through Collaborative Discourse
Authors: Bakar Ahmad Naqiyuddin , Mat Kamal Siti Nuur-Ila , Hosin Husnizam , Saud Nur Adilah
Published: April 2024

Despite abundant leadership research work, there is still a dearth of truly original, ground-breaking collaborative research discourse. To provide greater insights of linking various disciplinary paradigms and respond to this issue, we evaluate the leadership competency (LDC) model, proposed by Fowler et al. (2018). The paper analyse the different levels of leadership practices that lead to innovation with examples drawn from leadership studies. The model offers theoretical grounding as well as actionable guidelines for generating original research ideas. In response to the need felt by researchers on leadership, collaborative initiatives indeed has a dominant place in the contemporary leadership discourse.
Future Envisioning of Hybrid Political Order
Authors: Lopez Pedro , Yağcı Sait
Published: April 2024

Hybrid political order is a relatively new political concept for explaining a state-building reality observed in some new post-conflict states. Hybrid political orders and hybridity have evolved as a result of the emergence of fragile states that hardly function in the international system. The fragile states began to be characterized by post-modernity and did not fit in the classical model of the state. Thus, this paper explores the literature to demonstrate how hybrid political order functions within domestic governance than in the interaction with other states and in the international system. The purpose of this study is to examine a hybrid political order in the international system by exploring the determinants of legitimacy and recognition. Such exploration and analysis are in addition grounded on peace-building and state-building theories. This paper envisions the hybrid political order as a possible alternative for better functioning of the international system.
Connecting the Dots: Are the New Public Management and Policy capacity related?
Authors: Mohd Barakbah Nur Badrina , Zainuddin Azizan , Yaakob Ahmad Faiz
Published: April 2024

The New Public Management (NPM) and Policy Capacity (PC) have garnered significant attention in the field of public administration. NPM is frequently associated with market-based reforms and the privatisation of public services, whereas PC pertains to a government's ability to design, implement, and evaluate policies effectively. Despite the vast literature on these concepts, there remains a dearth of studies examining their connection. This paper seeks to bridge this gap by exploring the linkages between NPM and PC. Drawing from a comprehensive review of articles and journals, most studies revealed that the two concepts are indeed related in some way.
Implementation of Self-Perceived Identity for Gender Change: Issues of policy coherence and relevance towards transgender welfare in Pakistan
Authors: Hamzaiftikhar Hamzaiftikhar , Salleh Siti Hasliah , Mohamed Yusof Nor Ashikin
Published: April 2024

The gender change is legally permitted by Transgender (Protection of Rights) Act 2018, where the use of self-perception for the gender change remains controversial. The self-perception relevance, suitablility and coherence has the legal policy impact on the future of transgender act.This qualitative research using semi-structured interviews is conducted,as part of policy evaluation with the thematic analysis through NVivo software showing implementation of self-perception test lacking coherency and relevancy. The results highligted that socio-cultural, biological conditions, Islamic injunctions and principles as the main considerations that all parties consider before permitting gender change.Future research on evaluation of the self-perception identity is recommended.
India-Burma (Myanmar) Relations under British India Administration prior to 1937 Separation: Influx of Indians and Awakening of Nationalist Movements in Burma
Authors: Ayob Azman
Published: April 2024

The paper focuses on India-Burma relations under British India’s administration prior to the 1937 separation. As for data gathering, content analysis was adopted. The findings are analyzed through two perspectives: the influx of the Indians into Burma and the awakening of Burma’s nationalist movements related to Mahatma Gandhi. The findings of this study demonstrates that the influx of the Indian immigrants had eventually gave rise to the Burmese nationalist movements and the separation of Burma from British India was influenced by the Indian nationalists as well as a thought by Mahatma Gandhi that Burma cannot be part of India.
Sustainable Development Goal 7 (SDG 7) - Affordable and Clean Energy: A preliminary review of the Sarawak scenario
Authors: Chundi Timoti , Tuan Ismail Tuan Nooriani , Kassim Asiyah
Published: April 2024

The United Nations' Sustainable Development Goal 7 seeks to ensure universal access to affordable and clean energy for all. This paper reviews the progress and challenges related to SDG 7 implementation by focusing on Sarawak, Malaysia. To produce the energy needed to attract investments to propel its economy, Sarawak leverages on constructing mega-dams. In this context, the study observes the relationship between energy and economic growth. Drawing from a preliminary review of relevant literature, the challenges and opportunities remain wide. Hence, it underscores the importance of a context-specific approach if SDG 7 is to succeed
Work-life Balance and Job Performance: A case of Royal Malaysian Police
Authors: Hilwa Jun Nazlia , Tuan Ismail Tuan Nooriani
Published: April 2024

This study was designed to investigate the worklife balance and job performance among the Royal Malaysian Police (RMP). RMP faced various challenges due to nature of their work and pressured with high perception among societies for them to solve security related issues. This study used a purposive sampling of 380 RMP located in Kedah. Finding reveals that there exist a correlation between work-life balance (time balance, organisational support and workload) and job performance. All hypotheses are accepted as there is positive relationship between independent and dependent varaibles. Therefore, it can be concluded that work-life balance has impact on job performance.
Research on the Education Path of Art Majors Based on Innovative and Entrepreneurial Thinking Cultivation
Authors: Wang Xinying
Published: April 2024

With the development of society and technology, the importance of innovation and entrepreneurship ability has been greatly increased. How to cultivate art professionals with innovation and entrepreneurship ability is a major challenge faced by universities. Art majors generally have rich imagination and creativity. Cultivating innovative thinking can enhance their artistic cultivation and skills, while entrepreneurial thinking is conducive to breakthroughs in the application and promotion of art. However, there are still some problems in integrating innovative and entrepreneurial thinking into the art major at present, such as insufficient understanding of the importance of integrating the two in terms of ideology, the mechanism of innovation and entrepreneurship education in universities still needs to be improved, and a shortage of university teachers who are good at innovation and dare to innovate. Based on this, both universities and art majors should recognize the importance of innovative and entrepreneurial thinking, and take effective actions to achieve the organic integration of their majors and innovative and entrepreneurial thinking.
Modeling and analysis of a theoretical composite material for aerospace use
Authors: Saldaña Heredia Alonso , Martínez Calzada Víctor , Cosgalla Marín Cristina Lizete , Rodríguez Torres Adriana
Published: April 2024

The objective of this article is to present a composite material as a reusable element applied to the aerospace sector. The material is proposed to be part of a two-stage rocket, which will be subjected to both a thermal load due to liftoff and an axial load. For this, the material was simulated through a stress test following the ASTM standard and thermal expansion was studied through three theories. The answer was analyzed using two software: firstly, we used MATLAB® to analytically model the stress test and we focused on determining which would be the best proportion based on the rule of mixtures; likewise, we studied the effect of thermal expansion and proposed a cycle (takeoff-landing), in which material wear was considered as residual stress. The result of this first analysis was to obtain the best ratio (fiber-matrix) to subsequently model it in ANSYS®. In this software, the material was modeled defining itself as a laminated composite; we studied the difference between the number of sheets. Similarly, we analyze the material from an axial load test and adding the thermal load. As a result, it was found that the theoretical material could achieve maximum performance using four fiber sheets. Analytically calculated strains were analyzed through the mixture rule in MATLAB® and compared with those calculated numerically in ANSYS®. From this comparison, an accuracy of 99% was obtained using a polymeric composite laminated with four fiber sheets
Mejora de las perturbaciones de un sistema eléctrico mediante la automatización de los elementos de regulación
Authors: Murillo Rodríguez Virgilio Alfonso , Guirette Barbosa Omar Alejandro , Robles Solís José Manuel
Published: April 2024

Actualmente, el crecimiento acelerado en la integración de nuevos consumidores al sector eléctrico debido a la incorporación de nuevas empresas principalmente en el sector industrial ha llevado a la generación de un mejor control tanto en el suministro del servicio eléctrico como en las condiciones de operación y funcionamiento del usuario, siendo una responsabilidad conjunta el mantener una adecuada calidad en el servicio. Las perturbaciones en el sistema eléctrico sin ningún tipo de regulación presentan diferentes anomalías como perturbaciones, fallas, mal funcionamiento e interrupciones importantes en el sistema eléctrico, generando grandes gastos y pérdidas económicas. Esta investigación incorpora una nueva solución a través de la automatización de los elementos de regulación para mantener niveles adecuados de calidad del sistema y evitar daños y fallos en los equipos, ofreciendo un modelo rentable sometido a un sistema de simulación fiable en el software Etap (Modelado, análisis y optimización de sistemas energéticos), simulando el diseño del flujo eléctrico en la operación de los equipos emulando la interacción de los elementos de regulación. Los resultados mostraron mejor estabilidad en las perturbaciones del sistema cuando dos esquemas interactúan en la automatización: 1. - Operando sólo la batería de condensadores se mejoran las fluctuaciones totales de corriente del sistema, así como el factor de potencia, del 85,83% al 93,42%, mejorando asimismo la forma de onda en el sistema eléctrico principal; 2. - Mejorando las fluctuaciones de corriente del sistema, así como el factor de potencia, del 85,83% al 94,81%, mejorando asimismo la forma de onda en el sistema eléctrico principal, cuando se opera el filtro de tensión y corriente junto con el sistema fotovoltaico al mismo tiempo.
Efficient coil design for transcranial magnetic stimulation using computational tools
Authors: Ramirez Galindo Angel D. , Olivares Galván Juan Carlos , Corona Sánchez Manuel A. , Escarela Pérez Rafael , Melgoza Vazquez Enrique , Gonzalez Montañez Felipe de Jesús
Published: April 2024

In the last two decades, transcranial magnetic stimulation (TMS) has been used in research protocols and clinical treatment of neurological disorders. In this work, we analyze the heating of a transcranial magnetic stimulation equipment, with the aim of reducing it using a novel design of stimulation coils. The operation of the equipment is limited by the overheating of the stimulation coils, such that the continuous use of the equipment during the therapy is impossible, and the device´s life time is affected. The first stage of the analysis consists of studying the response of the electrical excitation circuit through simulations, considering the use of concentric inductors to divide the magnitude of the current. This is complemented by multiphysical analysis with coupling between the magnetic field and heat transfer of two different coil geometries, showing the spatial distribution of the generated magnetic field and temperature rise in the space surrounding the stimulation coil. The main contribution of this research is the design of a stimulation coil using the finite element method, reducing the device´s operating temperature considering a practical coil geometry.
Experimental Study and Analysis of Strength Properties and Sulfate Resistance of Self-Compacting Concrete Using Different Admixtures
Authors: Majeed Mr. Irfan
Published: April 2024

Abstract: The strength characteristics and sulfate resistance of self-compacting concrete (SCC) containing Class-F fly ash and metakaolin were investigated in an experimental study. Class-F fly ash and Metakaolin were added in varying proportions to the combinations, from 10% to 25%. The qualities were analyzed and discussed. These included the properties of both fresh concrete (slump flow, L-box, V funnel, and U-box) and hardened concrete (sulfate resistance and compressive strength). Class-F fly ash was used in self-compacting concrete (SCC) formulations, which showed 28-day compressive strengths between 30 and 40 MPa. The compressive strength decreased by 15.28% when cured in a MgSO4 solution as opposed to the control mix cured in water, with values ranging from 24 to 35 MPa. The compressive strength ranged from 34 to 54 MPa after curing in a MgSO4 solution, representing a 15.38% reduction from the control mix that was cured in water
To Assess the Impact of Web 3.0 and Metaverse Technologies on Business Administration
Authors: Koli Miss. Madhushri Pramod
Published: April 2024

Abstract: The concept of Virtual Enterprise (VE) involves collaborative efforts among businesses to boost competitive advantage in specific markets through joint ventures, aligned networks, or outsourcing. This collaboration leads to the development of a Virtual Model (VM) for operations. Web 3.0 and advancements in Information and Communication Technologies (ICT) hold the potential for reshaping business administration, enabling innovative virtual environments and process improvements. Web 2.0 initiated deeper consumer-web interactions, while Web 3.0, or the Semantic Web, enhances collaboration between computers and humans through well-defined information and logic-based reasoning. Metaverse technologies, linked to Web 3.0, introduce 3D environments and redefine online interactions, offering new opportunities for collaboration and enhanced reality applications
Comparative Analysis of Machine Learning Algorithms for Text-based Phishing Detection
Authors: Chavan Dr. Pundalik
Published: April 2024

Abstract: Phishing is a major threat to personal and organizational security. The risks associated with phishing have increased as cyber criminals devise more convincing methods to deceive their targets. Deceptive emails can often result in the compromise of personal information, accounts, financial loss and reputational damage. This paper explores how certain commonly used machine learning algorithms perform in detecting malicious emails based on the text alone. The algorithms analyzed are Support Vector Machines (SVM), Naive Bayes (NB) and Logistic Regression (LR). The paper compares the performance of these algorithms based on various factors such as accuracy, precision and recall. It also compares the performance of a voting approach with the algorithms.
Human Activity Recognition Using Smartphone and Smartwatch
Authors: Phunneshwar Praveen , Narang Shubham , Gurjar Lalit , Rane Shripad , Kamdi Dipmala
Published: April 2024

Abstract: Human activity recognition has many applications in medicine System of research and surveys among people. The recognition of human action has sparked great interest in both industry and academia in recent years. due to the widespread use of sensors such as accelerometers and gyroscopes in products such as smartphones and smartwatches. Activity recognition is currently used in various areas where it is valuable Information about the person's functional abilities and lifestyle is needed. We can do this using multivariate analysis of covariance (MANCOVA). found a statistically significant difference between the data generated by the sensors integrated into smartphones and smartwatches. This is how we show that smartphones and smartwatches Due to where it is worn, the does not record data in the same way. We have implemented several neurons network architectures that classify 15 different manual and non-manual activities. These models include long-term memory (LSTM), convolution neuron Network (CNN) and Convolutional LSTM (ConvLSTM). The models developed worked better with the watch Data from accelerometer. We also saw that the classification accuracy was achieved with the convolutional input (CNN and ConvLSTM) is found to outperform the full LSTM classifier. Additionally, the watch accelerometer CNN model was able to better classify non-wrist-facing watches. tasks compared to manually executed tasks