bluuebunny/crossref_metadata_2025 huggingface dataset:
Substrate-directed divergent annulations of sulfur ylides: synthesis of functionalized bispirocyclopentane and bispirocyclopropane derivatives
Authors: Chen Siyi , Liang Peiyao , Cai Yilin , Zhou Liejin , Wang Shoulei
Published: February 2024

A substrate-directed divergent [2+3]/[2+1] annulation of tetra-substituted oxa-dienes and allylic sulfur ylides has been developed for the synthesis of functionalized bispirocyclopentane and bispirocyclopropane derivatives.
Mn-doped RuO2 nanocrystals with abundant oxygen vacancies for enhanced oxygen evolution in acidic media
Authors: Zheng Caixia , Huang Bing , Liu Xuwei , Wang Hao , Guan Lunhui
Published: February 2024

Synthesizing Mn–RuO2-120(NaNO3) with abundant oxygen vacancies using the molten salt method enhances the oxygen evolution reaction (OER) catalytic performance, demonstrating excellent activity and stability.
Synthesis of enantiopure 1,2,3-triazolylidene-type mesoionic carbene (MIC) conjugate acids featuring a rigid bicyclic scaffold
Authors: Dočekal Vojtěch , Melaimi Mohand , Petrželová Simona , Veselý Jan , Yan Xiaoyu , Bertrand Guy
Published: February 2024

Chiral NHCs have found numerous applications as ligands for transition metals and in their own right for asymmetric catalysis. We report a synthetic route from l-malic acid to enantiopure 1,2,3-triazoliums with the chiral center in a fused ring.
Word-Final Disfluency: Clinical Data From a Single Therapy Protocol
Authors: Sisskin Vivian , Wasilus Samantha
Published: February 2024

Purpose:

Word-final disfluency (WFD), also referred to as
end-word repetition
and
echo dysphemia
, takes the form of a final rhyme repetition involving a whole or partial syllable (e.g., “lock-ock” and “ca-ake”). Although WFD has been documented in case studies, therapeutic programs have not yet been reported. Our purpose was to report therapy data for 20 cases of WFD using a single therapy protocol called Structured Awareness Therapy for Word-Final Disfluency. The authors report the effects of therapy in routine clinical practice and describe the therapy program to contribute practice-based evidence that may narrow the research–practice gap and improve service delivery for those with WFD.

Method:

The participants included 20 children (13 boys and seven girls; age range: 5–11 years). Parents reported a diagnosis of autism in five of the 20 participants. The children and their families participated in weekly and biweekly therapy sessions. Pre- and posttherapy spontaneous speech samples were analyzed and compared. Parents' responses to follow-up surveys were reported.

Results:

All 20 children had successfully reduced (to less than 1.5% WFD) or eliminated WFD in their spontaneous speech with short-term therapy (average, 9 weeks). Parental follow-up surveys confirmed the long-term durability of the therapy.

Conclusions:

Therapy data support the functional and long-term outcomes of the reduction or elimination of WFD in routine clinical practice. The authors described the therapy program and offered perspectives on the causes or functions of WFD. Suggestions for future directions include research needs and a call for treatment efficacy studies to broaden trusted therapy options for WFD.
A distributed robust state estimation method based on alternating direction method of multipliers for integrated electricity‐heat system
Authors: Chen Yanbo , Gao Yulong , Fang Zhe , Li Jiaqi , Hu Zhenda , Zou Yichao , Ma Jin , Li Chunlai , Xiao Qinze , Chen Zeyu
Published: February 2024

Integrated electricity‐heat system (IEHS) has been paid more and more attention in recent years for its advantage in improving energy efficiency, reducing carbon emissions and increasing renewable energy penetration. To ensure the safety, reliability and economic operation of IEHS, several centralised state estimation (SE) methods for IEHS have been proposed. However, power systems and heat systems often belong to different management entities, and there are industrial barriers such as information privacy, operational differences, and target differences between them, which leads to less applicability of centralised SE methods. In addition, the robustness of existing distributed SE methods for IEHS is not satisfactory. To this end, a distributed robust state estimation (DRSE) model for IEHS based on the alternating direction method of multipliers (ADMM) is proposed. Firstly, by introducing auxiliary state variables and measurements, a robust linear SE model based on weighted least absolute values (WLAV) is proposed. Then, second‐order cone constraints composed of auxiliary state variables are added to the SE model, leading a SOCP‐based robust SE model. Finally, the ADMM algorithm is used to solve the proposed SOCP‐based robust SE model. Simulations demonstrate that the proposed method has higher estimation accuracy in both general and strongly correlated adverse data tests and also can ensure data privacy, good robustness and high estimation accuracy. This indicates that the method proposed has good robustness and solves the problem of weak robustness of existing distributed static state estimation methods.
Optimal plug‐in hybrid electric vehicle performance management using decentralized multichannel network design
Authors: Mousavi Peyman , Ghazizadeh Mohammad Sadegh , Vahidinasab Vahid
Published: February 2024

In addition to providing mobility, plug‐in hybrid electric vehicles (PHEVs) provide a two‐sided energy exchange opportunity which makes them highly flexible distributed energy storage systems for the future of energy systems. This paper analyzes PHEVs' performance from the perspective of urban traffic and energy using a decentralized multichannel blockchain network based on the hyperledger model. This network using a layered design and local management of energy sources can significantly contribute to urban management and optimal use of its infrastructures. Then, dynamic modelling of PHEVs in this network is performed, and their data is added to the network to evaluate the network performance compared with the current centralized networks. The results indicated that the proposed blockchain network could simultaneously optimize PHEVs' performance, urban traffic management, and energy systems. Furthermore, by utilizing smart contracts, it can consider and optimize multiple challenges, such as congestion in the electricity network, urban traffic, and limited fuel, simultaneously. Therefore, it gives a strong tool to study the impact of mass deployment of PHEVs and their value and role in the sustainable cities and communities of the future while helping to support the global efforts toward affordable and clean energy for all.
A survey of feature matching methods
Authors: Huang Qian , Guo Xiaotong , Wang Yiming , Sun Huashan , Yang Lijie
Published: February 2024

Feature matching plays a crucial role in computer vision, with applications in visual localization, simultaneous localization and mapping (SLAM), image stitching, and more. It establishes correspondences between sets of feature points from multiple images, enabling various tasks. Over the years, feature matching has witnessed significant development, with an increasing number of methods being applied. However, different methods exhibit different degrees of applicability in different scenarios and requirements due to their different rationales. To cope with these issues, a comprehensive analysis and comparison of matching methods are essential. Existing reviews often lack coverage of deep learning models and focus more on feature detection and description, neglecting the matching process. This survey investigates feature detection, description, and matching techniques within the feature‐based image‐matching pipeline. Representative methods, their mechanisms, and application scenarios are also briefly introduced. In addition, comprehensive evaluations of classical and state‐of‐the‐art methods are conducted through extensive experiments on representative datasets. Particularly, matching‐based applications are compared to fully demonstrate the advantages of the methods. Lastly, this survey highlights current problems and development directions in matching methods, serving as a reference for researchers in the field.
Long-term dynamics around the Didymos–Dimorphos binary asteroid of boulders ejected after the DART impact
Authors: Langner K. , Marzari F. , Rossi A. , Zanotti G.
Published: February 2024

Context. In 2022, the DART mission spacecraft impacted the asteroid Dimorphos, the secondary body of the binary Didymos system, ejecting a large number of dust particles, rocks and boulders. The ESA Hera mission will reach the system in 2026 for post-impact studies and a possible detection of orbiting fragments.

Aims. We aim to investigate the long-term dynamics of the large boulders ejected by DART to test if any of these objects survive in orbit until the arrival of the Hera mission.

Methods. To model the dynamics of the boulders, we used a numerical model that includes the gravity of non-spherical Didymos and Dimorphos, the solar gravity, and the radiation pressure. The SPICE kernels are used to define the correct reference frame for the integrations.

Results. The dynamics of the boulders is highly chaotic, and 1% of the initial boulders survive at least for four years on quasi-stable orbits. These orbits are characterised by wide oscillations in eccentricity in antiphase with those in inclination (including spin flips), a mechanism similar to the Kozai one. This behaviour may protect these bodies from close encounters with both asteroids. We also computed the distribution on the surfaces of the asteroids of sesquinary impacts, which may influence the dust emission (after the initial DART impact) and the surface composition of the asteroids.

Conclusions. The probability of observing boulders by the mission Hera is small but non-negligible, and an almost constant flux of escaping boulders is expected in the coming years since their lifetime after the DART impact covers a large time interval. Most re-impacts on Dimorphos occur in the hemisphere opposite the impact site, preferentially close to the equatorial plane.
Lithium Cepheid V708 Car with an unusual chemical composition
Authors: Kovtyukh V. V. , Andrievsky S. M. , Werner K. , Korotin S. A. , Kniazev A. Y.
Published: February 2024

Aims. The purpose of this work is to spectroscopically analyse the classical Cepheid V708 Car. A preliminary check of the spectrum of V708 Car showed that this is a lithium-rich supergiant. We also found that V708 Car has an unusual chemical composition in that the abundances of various elements correlate with their condensation temperatures. We tried to find an explanation of this feature, which is unusual for classical Cepheids.

Methods. For the spectroscopic analysis, we used methods based on the assumption of local and non-local thermodynamic equilibrium.

Results. We determined the fundamental parameters of our program star V708 Car. This long-period Cepheid has a mass of about 12 M⊙. We derived the abundances of 27 chemical elements in this star. They are clearly correlated with their condensation temperature: the higher the condensation temperature, the lower the abundance (there are exceptions for sodium and barium, however). We explain this peculiar chemical composition of the V708 Car atmosphere by the gas–dust separation in the envelope of this star. A similar mechanism leads to the observed peculiarities of the chemical composition of λ Boo, W Vir, and asymptotic giant branch stars.
Effect of stocking density on larval performance and post-larvae settlement of clam Ruditapes decussatus (Linnaeus, 1758) in bivalve hatchery production
Authors: Azirar Rania , Janah Hafsa , Aghzar Adil , Ouagajjou Yassine
Published: February 2024

Larval rearing is a critical phase in bivalve hatchery production and plays a crucial role in the success of spat production. Therefore, understanding the effect of density on larval performance and post-larvae settlement is crucial for optimizing and improving the success of bivalve hatchery production. This study aimed to evaluate the effect of different stocking density on larval performances and settlement rate of clams Ruditapes decussatus. Three different larval rearing densities (10, 20, and 40 larvae/mL) and four settlement densities (35, 70, 100, and 140 larvae/cm²) were studied. The results regarding larval performance showed that high density resulted in low larval survival (18% for D40) compared to low and moderate densities (23% for D10 and 26% for D20, respectively). In terms of post-larvae settlement, a density of 35 larvae/cm² exhibited the highest fixation rate (36%) compared to 33%, 18%, and 9% at 70, 100, and 140 larvae/cm², respectively. Statistical analysis revealed a significant effect of larval density on both survival and growth (F = 11.79, p < 0.05; F = 18.63, p < 0.05, respectively), as well as a highly significant effect on settlement (F = 14.88, p < 0.001). Overall, it is advisable to maintain moderate densities during both larval performance and post-larvae settlement for seed production of R. decussatus in the hatchery.
Characterization of the tree length structure of the Nectarine tree before flowering by metric measurements in Sefrou, Morocco
Authors: Zegoumou Abderrahim , Ibriz Mohammed , Bounsir Badr , El Housni Zakariae , Amlal Fouad , Ait El Kassia Abdelaziz , Asfers Adil , Drissi Saad , Fagroud Mustapha
Published: February 2024

This study aims to describe the architecture of Nectarine fruit trees located in Sefrou region. This characterization concerned the length variation of all the tree structure before flowering by metric exhaustive and non-destructive measurements. The study conducted on Nectarine variety of Spring Bright, by measuring 10 trunk, 40 frames, 157 1st underframe, 280 2nd underframe, 361 3rd underframe, 308 4th underframe, 134 5th underframe and 1250 of mixed branches, that have been labelled and numbered. The characterization of the tree revealed the underlying logic of the plant’s construction, The lengths, decrease from scaffold to 5th level under frame but it experiences a 357% increase in length ratio for the mixed branch due to its role as the primary fructification structure. This type of distribution is logic for the goblet training pruning program. The mean number of structure evolution was (scaffold) 4/(1st level) 4/(2nd level)1/3rd level 2/(mixt branch) 9 . The raw length data was not homogeneous probably due to the pruning effect, so they were grouped in three to four class to enhance the homogeneity.
Optimization of the deficit irrigation management for strawberry production in the Loukkos region
Authors: Elmidaoui Kenza , Abouabdillah Aziz , Fagroud Mustapha , Bouabid Rachid
Published: February 2024

The Moroccan red fruit sector has undergone remarkable development over the last decade, driven by the increase in demand from international markets and promoted by the national agricultural strategy. However, this development calls for the sustainability of water resources, especially in the current context of climate change which makes the future availability of water uncertain. In this sense, deficit irrigation (DI) is one of the promising techniques to improve the efficiency of crop water use. Strawberry is one of the most sensitive red fruits to water deficit. Sufficient and correct irrigation is critical to successful production. Therefore, growers often bring in quantities that exceed the needs of the crop, especially in areas where the cost of water is relatively negligible. In this paper, we studied the response of the two strawberry varieties (Sabrina, Victory) to four water treatments ranging from 50% to 125% of crop evapotranspiration (ETc). The two varieties differed significantly in yield and water consumption, with significant reductions in yield under DI treatments (50%ETc) for Sabrina. However, the fully irrigated treatment (100% ETc), and the DI treatments (75% and 50% ETc) did not show significant differences in yield for Victory.
Treated waste water reuse in agriculture: An Overview
Authors: Boularbah Sara , El Khoumsi Wafae , Bourziza Rqia , Bourioug Mohamed , Abouabdillah Aziz
Published: February 2024

The reuse of treated wastewater in agriculture is a promising solution to the water scarcity challenge faced by many regions worldwide. This review paper provides an overview of the current state of knowledge on treated wastewater reuse in agriculture, highlighting its potential benefits and challenges. The paper begins by discussing the importance of treating wastewater before reuse and the potential it offers. The benefits of using treated wastewater in agriculture are discussed, including increased water availability, improved soil fertility and reduced fertilizer use. The risks associated with the use of treated wastewater, such as the accumulation of pollutants and the potential for pathogen transmission, are also discussed. The review paper then presents some examples of reuse projects for irrigation and their success criteria. The current regulations governing the use of treated wastewater in agriculture are examined, and their evolution presented. The paper concludes with a discussion of future research needed to address the remaining challenges surrounding the use of treated wastewater in agriculture. Overall, the review paper emphasizes the importance of careful management and regulation of treated wastewater reuse in agriculture to ensure safety and sustainability to meet the growing demand for water in agriculture.
Cystic meningioma of the brain
Authors: Long Jiang
Published: February 2024

Meningiomas with a cystic component are quite rare and account for 1.7–7.3 % of all intracranial meningiomas. The incidence of cystic meningioma in adults is 2–4 % of all meningiomas. Women have a higher incidence rate in comparison to men. Between 2014 and 2019, at the State Institution Romodanov Neurosurgery Institute of the National Academy of Medical Sciences of Ukraine, we collected data for a database of cystic meningioma cases. The data included preoperative imaging, surgery notes, and pathology reports. Over the course of 6 years, 1408 meningioma cases have been observed, and 1326 of those instances have undergone surgical treatment for intracranial meningioma. 73 (5.5 %) cases of cyst-associated meningiomas have been analyzed: 26 (2.0 %) of true cysts (primary), 47 (3.5 %) cases of pseudocysts (secondary). Nauta type IV was the most common cyst type accounting for 52.1 %, whereas atypical (27.4 %) and anaplastic (17.8 %) meningioma types were the most common histological subtypes. All patients were monitored for 24 months; only 73 patients had access to long-term monitoring, which lasted for an average of 49 months (range 36–96 months). The majority of atypical (2.7 %) and anaplastic (5.5 %) types of pseudocystic meningioma relapsed after radical tumor surgery removal. The preoperative diagnosis needs to be integrated with the examination performance, the surgical treatment is selected based on the Nauta classification, and most of the surgical operations can result in the complete resection of the tumor.
Sehr geehrte Leserinnen und Leser, liebe Kolleginnen und
Kollegen
Authors: Klüter Harald
Published: February 2024

die Blutspende ist und bleibt ein unschätzbar wertvoller Beitrag, mit dem
Blutspendende Patientinnen und Patienten zur Gesundung verhelfen oder ein
Weiterleben ermöglichen. In Anerkennung dieser uneigennützigen
Hilfeleistung verpflichten sich die in der Transfusionsmedizin wirkenden
Fachkräfte zu einer umfassenden Betreuung der Spendenden, zu einer
sorgfältigen Untersuchung der Blutspenden und zu einem verantwortungsvollen
Umgang mit den Blutprodukten bei der Weiterverarbeitung, Lagerung und
Verteilung.
Moderne Methoden der Blutaufbereitung
Authors: Boecker Clemens , Giss Alexander , Johnsen Matthias
Published: February 2024

Vollblutspenden werden nach der Entnahme in Blutspendediensten zu den
Blutkomponenten Erythrozytenkonzentrat, Therapeutisches Plasma und
Thrombozytenkonzentrat weiterverarbeitet. Die Verarbeitung kann auf verschiedene
Weise erfolgen. In diesem Übersichtsartikel erläutern wir die
Unterschiede zwischen den beiden weltweit gebräuchlichsten Verfahren,
dem Buffy-Coat-Verfahren und dem Plättchen-Reiches-Plasma-Verfahren, und
beschreiben das in Deutschland standardgemäß eingesetzte
semi-automatisierte Buffy-Coat Verfahren detaillierter. Darüber hinaus
werden die verschiedenen Automatisierungsgrade in der Vollblutverarbeitung und
die verschiedenen Ansätze zur weiteren Automatisierung beleuchtet. Im
Rahmen dessen zeigen wir auf, welche Automatisierungsmaßnahmen in
einigen Einrichtungen bereits umgesetzt werden konnten und welche neuen
Techniken die weitere Automatisierung in Zukunft entscheidend prägen
könnten.
Physiologie und Epigenetik der Großhirnentwicklung
Authors: Hermann Wieland
Published: February 2024

Haut und Nervensystem verbindet ein gemeinsamer embryonaler Ursprung. Die Kenntnis der Ableitung des Nervensystems aus dem Ektoderm ist wichtig für das Verständnis neuroektodermaler Syndrome. Die pränatale Entwicklung führt zu einem Nervensystem entsprechend eines evolutionär definierten genetischen Plans ohne seine vollständige Leistungsfähigkeit zu erreichen. Dieser Zustand dient als Basis für die postnatale Entwicklung aller psychischen, geistigen und ideellen Bewusstseinsprozesse. Das damit verbundene Weiterwachsen des Gehirns gilt als Besonderheit des Menschen und heißt sekundäre Altrizialität. Parallel kommt es zur Ausreifung des neuronalen Netzwerkes mit Abschluss um das 20. Lebensjahr. Bis dahin, besonders zwischen dem 2. und 10. Lebensjahr besteht eine hohe Neuroplastizität, die für das Erlernen sozialer, kognitiver und motorischer Fähigkeiten wichtig ist. Später kann dies nur schwer oder unvollständig nachgeholt werden. Die erreichbare Leistungsfähigkeit des Gehirns ist somit maßgeblich von der Epigenetik postnatal bestimmt, und nur die Grundlage ist pränatal genetisch determiniert.
„Früher haben wir in der Neuroreha Rezepte befolgt, um Diagnosen zu behandeln“ – Interview mit Peter Oesch
Authors: Janssen Christina
Published: February 2024

Dr. phil. Peter Oesch ist Physiotherapeut, bereits seit mehr als 40 Jahren in der Neurorehabilitation tätig und leitete zuletzt die Therapien der Kliniken Valens in der Schweiz. Er berichtet Christina Janssen von den Veränderungen, die er in der Neuroreha während seines Berufslebens beobachtet hat und welche Herausforderungen auf künftig tätige Therapeut*innen aller Professionen zukommen werden.
Trainingsprogramm fürs Homeoffice – Wissenschaft nachgefragt
Authors: Veit Katrin
Published: February 2024

Im Homeoffice produktiv und gleichzeitig gesund und schmerzfrei zu bleiben, ist eine Herausforderung für viele Arbeitnehmende. Die Ursachen eines Low Back Pain und damit einhergehenden gesundheitlichen Risikofaktoren sind vielschichtig und reichen von Bewegungsmangel über Stress bis hin zu psychischen Belastungen. Lucie Berg adressierte dieses Problem deshalb in ihrer Bachelorarbeit und untersuchte, ob ein Trainingsprogramm für zu Hause Abhilfe schaffen kann.
Lernen braucht Emotionen – Neurodidaktik in der Physiotherapie-Ausbildung
Authors: Tuena-Küpfer Simone
Published: February 2024

Lernen ist lebenslang möglich, der Lernprozess aber ist hochindividuell. Die Neurowissenschaften zeigen, wie wichtig positive Gefühle für das effektive Lernen sind. Simone Tuena-Küpfer nimmt uns mit auf eine spannende Reise durch unser Gedächtnis. Sie zeigt, wie Lehren und Lernen am besten klappt und welche neuen Wege damit für eine gehirngerechte Ausbildung entstehen.
Entstehung von Triggerpunkten
Authors: Mense Siegfried
Published: February 2024

Zur Pathophysiologie von Triggerpunkten wird nach wie vor viel geforscht. Studien bestätigten, dass eine Energiekrise bei der Entstehung eine wichtige Rolle spielt. Neuere Erkenntnisse ergänzen das Modell. Dieser Refresher bringt Sie auf den neuesten Wissensstand. Im Mittelpunkt stehen muskuläre Triggerpunkte.
Leerstellen – Berufsflucht aus der Heilmittelbranche
Authors: Reck Stefan
Published: February 2024

Der Fachkräftemangel betrifft nahezu alle Gesundheitsberufe. Im Gegensatz zu Medizin und Pflege findet die Heilmittelbranche keine Beachtung in den Medien. Da der grundsätzliche Bedarf an Fachkräften schwierig zu ermitteln ist, können die Heilmittelerbringer ihre Verhandlungsposition für bessere Bedingungen nur schwer stärken.
Einfluss der Covid-19-Pandemie auf die sportmotorische
Leistungsfähigkeit und den BMI von Grundschulkindern der 2.
Klasse
Authors: Schoser Daria Sophia , Schumacher Felix , Froböse Ingo , Wilke Christiane
Published: February 2024

Die Covid-19-Pandemie führt mit Maßnahmen wie der
Schließung von Sporteinrichtungen und dem Ausfall des
Präsenzunterrichts zu starken Einschnitten und Veränderung der
Bewegungsgewohnheiten. Aufgrund der diskutierten Möglichkeit
langfristiger Folgen dieser Maßnahmen für die Kinder in
Deutschland wird eine Trendstudie mittels Panelerhebung mit Daten aus den Jahren
2019 und 2022 durchgeführt, um eine mögliche Veränderung
der sportmotorischen Fitness und des BMIs zu ermitteln. Die Daten werden mit
Fragebögen und dem motorischen Testinstrument „CHECK!“
erhoben und umfassen die Daten von 2437 Grundschüler*innen der
zweiten Klasse aus allen 26 Grundschulen einer Großstadt. Die
Mittelwerte der Items aus dem sportmotorischen Test wurden mit einem t-Test
für unabhängige Stichproben überprüft.
Zusätzlich wurden, angelehnt an den Schulscharfen Sozialindex, ungleiche
Schulstandorte in Subgruppen explorativ miteinander verglichen.
Übergreifend nahm die aerobe Ausdauer, gemessen mit einem
6-Minuten-Lauf, ab. Die Ergebnisse in Bezug auf die Kraft verbesserten sich im
Vergleich zur Gruppe vor der Pandemie. Die Ergebnisse für Schnelligkeit,
Flexibilität und Koordination zeigten keine statistisch signifikanten
Veränderungen. Hinsichtlich sozioökonomischer Unterschiede wird
eine Verschlechterung des BMIs der Subgruppe schwacher sozioökonomischer
Schulstandort im Jahr 2022 erkannt. Diese Subgruppe schneidet sowohl im Jahr
2019 als auch im Jahr 2022 in fast allen Testitems der sportmotorischen Leistung
schlechter ab. Es lassen sich übergreifend Hinweise finden, dass sich
lediglich die aerobe Ausdauer zu der Zeit vor der Pandemie verschlechtert hat.
Der sozioökonomische Schulstandort weist 2022 verstärkt ein
Anzeichen auf eine Verschlechterung der sportmotorischen
Leistungsfähigkeit sowie des BMI auf und sollte für
zukünftige Fördermaßnahmen in den Blick genommen
werden.
Innovative Prozesskette zur Sicherung der Erwerbsfähigkeit
nach endoprothetischem Gelenkersatz
Authors: Gernert Madeleine , Dejonghe Lea A.L. , Schöttler Marc , Schaller Andrea
Published: February 2024

In der postoperativen Versorgung nach Hüft- und Kniegelenkersatz ergeben
sich oftmals durch eine eingeschränkte Rehabilitationsfähigkeit
von Patient*innen Herausforderungen für die inhaltliche
Ausgestaltung der stationären Anschlussrehabilitation. Um
Patient*innen besser auf die Anschlussrehabilitation vorzubereiten und
in der Folge die Wiedereingliederung ins Berufsleben zu verbessern, werden im
Modellprojekt ProSEeG zwei innovative Therapiemodule entwickelt und evaluiert.
Im vorliegenden Beitrag werden diese innovativen Therapiemodule sowie das
Evaluationskonzept des Modellprojektes vorgestellt.
Stationäre Behandlung bei älteren Patienten mit
Rückenschmerzen unter Berücksichtigung der Möglichkeit
der multimodal-nichtoperativen Komplexbehandlung – Erfahrungsbericht aus
einem Kompetenzzentrum
Authors: Kladny Bernd , Haase Ingo
Published: February 2024

Kreuzschmerzen sind insbesondere bei älteren Menschen häufigste
Ursache für Funktionseinschränkungen. Wenn die Erreichung der
Behandlungsziele unter ambulanten Bedingungen nicht gewährleistet ist,
besteht die Möglichkeit nichtoperativer orthopädischer
Krankenhausbehandlung, entweder im Rahmen diagnosebezogener Fallgruppen (DRGs)
oder im erweiterten Rahmen multimodal-nichtoperativer Komplexbehandlung, an
deren Abrechnung strukturell, diagnostisch und therapeutisch höhere
Voraussetzungen geknüpft sind. Neben einer Darstellung der
Möglichkeiten multimodal-nichtoperativen Komplexbehandlung berichten wir
über Erfahrungen hinsichtlich Patientenstruktur und Behandlungsergebnis
auf der Basis von Daten aus den Jahren 2018 und 2019. Es zeigt sich, dass auch
ältere Patienten von der konservativen stationären Behandlung
ihrer Rückenschmerzen profitieren, Die Verläufe der
älteren Patienten, sei es in DRG- oder in Komplexbehandlung,
unterscheiden sich nicht auffällig von den jüngeren Patienten
(Kruskal-Wallis-Test mit post-hoc-Tests, p-Werte>0,1), allerdings bleibt
die Funktionskapazität auf niedrigerem Niveau.
Neutrophil-lymphocyte ratio: an independent predictor of the herpes
zoster risk in rheumatoid arthritis patients treated with
tofacitinib
Authors: Liu Pengcheng , Zhang Min , Zhang Yueqin , Yu Shujiao , Wu Rui
Published: February 2024

To investigate the role of the neutrophil-lymphocyte ratio (NLR) in the risk of
developing herpes zoster (HZ) in patients with rheumatoid arthritis (RA)
receiving tofacitinib. This was a prospective observational study recruiting
patients who were diagnosed with RA and treated with tofacitinib. Patients with
previous herpes zoster infections were excluded from this study. All patients
were assessed for HZ every 1–3 months and were followed up for 12 months.
Univariate and multivariate logistic regression analyses were used to assess the
relationship between NLR and HZ. A cutoff value of NLR was determined based on
an ROC curve. A total of 277 patients were included in this study, 19 of whom
developed herpes zoster. Univariate and multivariate logistic regression
analyses showed that NLR (OR=19.813, p<0.05), neutrophils (OR=15.521,
p<0.05) and lymphocytes (OR=0.001, p<0.05) were independent influencing
factors of HZ. Through the analysis of the ROC curve, it was found that
neutrophils, lymphocytes and NLR had a high predictive value for HZ (AUC=0.75;
AUC=0.76; AUC=0.94). The cutoff values were 4.46*10^9/L, 1.70*10^9/L and 3.24,
respectively. Given that the NLR is easy to test, NLR was also expected to be a
very promising quantitative biomarker for predicting the risk of developing
herpes zoster in patients with RA receiving tofacitinib.
Diagnostic accuracy of artificial intelligence-enabled vectorcardiography versus myocardial perfusion SPECT in patients with suspected or known coronary heart disease
Authors: Aydar Simon , Knobl Hermann , Burchert Wolfgang , Lindner Oliver
Published: February 2024

Aim The present study evaluated with myocardial perfusion SPECT (MPS) the diagnostic accuracy of an artificial intelligence-enabled vectorcardiography system (Cardisiography, CSG) for detection of perfusion abnormalities.

Methods We studied 241 patients, 155 with suspected CAD and 86 with known CAD who were referred for MPS. The CSG was performed after the MPS acquisition. The CSG results (1) p-factor (perfusion, 0: normal, 1: mildly, 2: moderately, 3: highly abnormal) and (2) s-factor (structure, categories as p-factor) were compared with the MPS scores. The CSG system was not trained during the study.

Results Considering the p-factor alone, a specificity of >78% and a negative predictive value of mostly >90% for all MPS variables were found. The sensitivities ranged from 17 to 56%, the positive predictive values from 4 to 38%. Combining the p- and the s-factor, significantly higher specificity values of about 90% were reached. The s-factor showed a significant correlation (p=0.006) with the MPS ejection fraction.

Conclusions The CSG system is able to exclude relevant perfusion abnormalities in patients with suspected or known CAD with a specificity and a negative predictive value of about 90% combining the p- and the s-factor. Since it is a learning system there is potential for further improvement before routine use.
Synthesis of Racemosin B and Its Analogues by a Photochemical Cyclization
Authors: Nagarajan Rajagopal , Wazir Irfan
Published: February 2024

A simple approach for the synthesis of the alkaloid racemosin B has been developed through a photochemical cyclization reaction with a 33% overall yield without any reagents. This method is sustainable and environmentally friendly because no reagents are required to effect the transformation.
Importance of Multimodal Spinal Cord Monitoring and Hemodynamic Augmentation during High Thoracic Ventral Dural Tear Repair Using the Posterior Approach
Authors: Mariappan Ramamani , Thomas Sajo , Raju Krishnaprabhu
Published: February 2024

Cerebrospinal fluid (CSF) leakage due to large ventral dural tears (VDT) often requires surgical intervention. Surgical closure of a high thoracic VDT is challenging and associated with high morbidity, especially if it is performed after multiple epidural blood patch (EBP)/fibrin glue injections. A 44-year-old woman was diagnosed with spontaneous intracranial hypotension due to VDT at T1-T2, causing CSF leakage. Multiple EBP and fibrin glue injections failed to treat her symptoms; hence, the patient underwent surgical closure using the posterior approach. The patient was anesthetized using standard anesthetic drugs and was maintained under total intravenous anesthesia to facilitate continuous motor-evoked potential (MEP) monitoring. The surgical course was complicated by bleeding, hypotension, and MEP loss. Continuous MEP monitoring, effective team communication, quick restoration of blood pressure(BP) and BP augmentation with fluid, blood, and vasopressor helped to restore the MEP back to baseline. Hence, the patient recovered without neurological morbidity. This case report highlights the importance of adequate vascular access, multimodal spinal cord monitoring, and BP augmentation during a high thoracic VDT repair.
Association between Social Jetlag and Objective Physical Activity among Female University Students of Japan: A Cross-Sectional Study
Authors: Shibata Masashi , Fujibayashi Mami , Shibata Shiori , Kuzuhara Kenji , Tanida Keiko
Published: February 2024

Objective Discrepancies between sleep timing on work/school and free days, also known as social jetlag (SJL), can cause health problems. These issues occur most often in individuals from adolescence to the early 20s, which is equivalent to the age of university students. This study was designed to explore the recommended level of physical activity required to minimize SJL and to examine the relationship between SJL and objective physical activity among female university students.

Methods We assessed the SJL of 68 female students using the Japanese version of the Munich Chronotype Questionnaire. The objective physical activity and sleep variables of subjects were also evaluated at 3 to 4 weeks using a small triaxial accelerometer.

Results A significant negative correlation was found between SJL and physical activity on both free (r = − 0.435, p < 0.001) and school days (r = − 0.341, p < 0.01). According to the linear regression analysis, physical activity of 11,174 steps on school days and 10,713 steps on free days had the lowest SJL value. Total sleep time on free days had a significant positive correlation with SJL (r = 0.399, p < 0.001) and a negative correlation with physical activity (r = − 0.520, p < 0.001).

Discussion Our results suggest that substantial SJL may cause chronic fatigue and lead to a low level of physical activity in female university students. These results also imply that the recommended level of physical activity necessary to minimize SJL among these students is around 11,000 steps on both school and free days.
Diphallia — a Case Report
Authors: Bilwani P. K.
Published: February 2024

A case of Diphallia with associated other anomalies has been presented. The literature on the subject has been reviewed. The views of vatious authors, regarding the developmental aetiology of this rare congenital anomaly, have been described.
Penile Horn After Chronic Ulcer*
Authors: Bhargava J. S. , Keswani R. K. , Goyal S. L. , Gupta D. K.
Published: February 2024

A case of penile horn over preexisting chronic ulcer has been reported. Penile horn was treated by local excision but recurrence occurred after 3 months, for that partial amputation of penis was done.
Congenital Short Urethra (Chordae Without Hypospadias) One Stage Correction
Authors: Prakash Satya , De'Sa Oswald
Published: February 2024

A one stage repair for Congenital short Urethra is reported. Incidence, actological factors and principles of management are discussed.
Congenital Double Lip
Authors: Gupta I. J. , Bhatnagar S. K.
Published: February 2024

Report of 3 cases of congenital double lip with transverse elliptical excision of the buccal fold.
Uncommon Manifestations of Filariasis
Authors: Bhattacharya V. , Sinha J. K. , Tripathi F. M.
Published: February 2024

We present in this paper some of the unusual manifestations of filariasis. Surgery remains the sole modality of treatment along with conscrvative measures.

The skin of the scrotal neck and, if necessary, the skin flap from the thigh, are the best means to reconstruct the scrotum and cover the testes.
Reconstruction of Vagina in Cases of Vaginal Agenesis With Normal Uterus
Authors: Tiwari I. N. , Seth H. P. , Narayanan R. , Nayak P. N.
Published: February 2024

3 young women have been successfully operated by a modified Mc. Indoe technique of vaginoplasty. The result has been satisfactory from the poiont of view mestruation and sexual intercourse. It remains to be seen, whether they conceive in due course of time.
Reconstruction of Upper and Lower Lip Defects
Authors: Chandalia B. S. , Yadav R. G.
Published: February 2024

Our study of 30 cases of reconstruction of lip is reported. Various methods used by us for reconstruction are described.
Use of Limberg's Transposition Flap in Reconstructive Surgery
Authors: Rao Mohan
Published: February 2024

Experience with the use of a Limberges trans position flap on 20 occation in decribed, the defects reconstrected have all been square in shape unlike 60° rhomboid as originally described by Limberg.
A Study of Mortality in Burns (A review of 1513 cases)
Authors: Sinka Prof. R. C. , Verma Dr. S. K.
Published: February 2024

1. Mortality among 1513 cases of burns admitted in Patna Medical college Hospital, TUnder Plastic Surgery Department from Jan., 1970 to Dec., 1979 were reviewed.

2. 60.62% of the cases were of major burns (above 30%), 14.34% were between 15% to 30% and 25.04% were below 15%.

3. There was a total mortality of 498 cases out of which 213 were males and 385 were females with an overall mortality of 37.7% in males and 30.5% in females.

4, 86.97% of the cases had received the burn injury due to cloth catching fire and the accident was preventable.

5. 40.2%, of the cases were from the age group 12 to 45 years. 24.8%, above 45 years and 18.4 below 12 years.
Role of Collagen Sheet as a Temporary Cover for Raw Area—An Experimental Study
Authors: Krishnan Dr. R. , Goel Dr. T. C. , Bhatnagar Dr. S. K. , Kumar Dr. Mahender
Published: February 2024

1. Collagen sheet is very useful in preventing exogenous infection.

2. It promotes rapid epithelization in thickness raw areas, by protecting it from infection and the sheet is ultimately cost off.

3. Solit thickness skin grafts do not take up in cases of partial thickness skin loss. The wound epitheli it casts off.

4. Ointment dressings are prone to infection (57%) and they need frequent charges unlike collagen sheet.

5. Small, clean, full thickness raw areas covered with collagen sheet take lesser time to heal completaly (28 days), compared to those treated with conventional dressings (35-45 days).
Epidemiological Study Of Hypospadias
Authors: Dr Bariar L. M. , Dr Sinha J. K. , Dr Tripathi F. M. , Dr Bhattacharya V.
Published: February 2024

An analysis of 76 cases of hypospadias of all types treated during the period 1975 to 1980 is presented. The mean number of new patients attending the outdoor per year was 13.2. Maximum number of cases (41 percent) presented during first five years of their life. Four percent of the cases had chordee without hypospadias. Seventy Three percent cases belonged to distal types and 27 percent to proximal types. The various morphological features were noted in detail. Assocjated penile hypoplasia was seen in high percentage of cases and 6 per cent cent patients with hypospadias of proximal types had bifid scrotum.
Observaticns On The Treatment Of Ganglion With Intralesisonal Injection Of Hyaluronidase
Authors: Saha Dy. Ila , Biswas Dr. P. C. , Gupta Dr. S. , Polle Dr. N. P. , Ganguly Dr. A. C.
Published: February 2024

110 cases of simple ganglion were treated by aspiration and injection therapy by Hyalu-ronidase, out of which 74 cases could be followed up for 3 months to one and half year, rest 36 were lost to follow up. Out of the 74 rest 36 were lost to follow up. Out of the 74 follow up and 6 cases had recurrence, & did not respond to the treatment.
Post Burn Neck Contracture (A Study of 64 cases)
Authors: Dr Yadar R. G. , Bafna Dr. Yogesh , Chandalia Dr.
Published: February 2024

The principal methods involved in correction of cervical burn contracture have been described. Our study of 64 cases of post burn contracture of neck which have been treated by split skin graft (S.S.G) and use of U-Foam splint to prevent S. S. G. contracture is presented.
Mobile Technologies for Monitoring Sleep Time: A Systematic Search of App Stores in Brazil
Authors: Lemes Lorena Caligiuri , Triches Maria Isabel , Carvalho Cristiano , Cardoso Viviane de Freitas , Sato Tatiana de Oliveira
Published: February 2024

Introduction Decreased sleep time is detrimental to physical and mental health, exerting negative impacts on daily functioning and quality of life. Mobile health (mHealth) applications can be useful for improving sleep quality.

Objective To perform a systematic search of mHealth applications for monitoring sleep time at Brazilian online stores and evaluate the selected applications in terms of engagement, functionality, aesthetics, and quality of information.

Methods A systematic search was performed at the Google Play Store and the App Store developed or updated between 2020 and 2022. The mobile app rating scale (MARS) was used to assess their quality. The characteristics and information of these applications were presented. Data were analyzed descriptively.

Results Among the 2,264 relevant mHealth apps identified, 11 were eligible for inclusion. There was one app that offered only sleep time recordings, three offered sleep recordings and educational content, three monitored sleep time with audiovisual resources, two offered sleep time recordings with a focus on monitoring snoring, and two offered sleep time monitoring with individual content customizations. The apps scored fair on MARS, with a mean of 3.5 points (standard deviation: 0.8) on a scale of 1 to 5. Most apps scored low due to poor evidence-based information, aesthetics, and engagement.

Conclusion Although the use of mHealth technologies for monitoring sleep time has considerable potential for investigation, it is a relatively new, underexplored topic. Collaboration between researchers, clinical professionals, patients, and application developers is necessary for the creation of new evidence-based mHealth applications focused on Brazilian users.
Risk Factor Analysis for 30-day Mortality After Surgery for Infective Endocarditis
Authors: Jussli-Melchers Jill , Friedrich Christine , Mandler Kira , Alosh Mohamad Hosam , Salem Mohamed Ahmed , Schoettler Jan , Cremer Jochen , Haneya Assad
Published: February 2024

Background Infective endocarditis (IE) remains a challenging disease associated with high mortality. Several scores have been suggested to assess surgical risk. None was sufficiently adequate. We therefore analyzed risk factors for 30-day mortality.

Methods A total of 438 consecutive patients had surgery for IE in our department between 2002 and 2020. Patients were divided into two groups, one consisting of 30-day survivors (362 patients; 82.6%) and one of nonsurvivors (76 patients; 17.4%). Logistic regression analysis on pre- and intraoperative risk factors was performed and the groups were compared by univariable analyses.

Results Patients in mortality group were older (69 [58, 77] vs. 63 [50, 72] years; p < 0.001), EuroSCORE II was higher (24.5 [12.1, 49.0] vs. 8.95 [3.7, 21.2]; p < 0.001) and there were more females. More frequently left ventricular function (below 30%), preoperative acute renal insufficiency, chronic dialysis, insulin-dependent diabetes mellitus, NYHA-class IV (New York Heart Association heart failure class IV), and cardiogenic shock occurred. Patients in the mortality group were often intensive care unit patients (40.8 vs. 22.4%; p < 0.001) or had a preoperative stroke (26.3 vs. 16.0%; p = 0.033). In the nonsurvivor group Staphylococcus aureus was prevalent. Streptococcus viridans was common in the survivor group as was isolated aortic valve endocarditis (32.9 vs. 17.1%; p = 0.006). Prosthetic valve endocarditis (PVE) and abscesses occurred more often in nonsurvivors. In the logistic regression analysis, female gender, chronic dialysis, cardiogenic shock, and NYHA IV and from intraoperative variables PVE, cardiopulmonary bypass time, and mitral valve surgery were the strongest predictors for 30-day mortality.

Conclusion This study indeed clearly indicates that significant risk factors for 30-day mortality cannot be changed. Nevertheless, they should be taken into account for preoperative counselling, and they will alert the surgical team for an even more careful management.
High thermoelectric performance in polycrystalline Yb3Ge5 thin films
Authors: Ishiyama T. , Ozawa T. , Saitoh N. , Yoshizawa N. , Suemasu T. , Toko K.
Published: February 2024

The development of eco-friendly thin-film thermoelectric generators for microenergy harvesting applications is highly desired. Ge-based materials have recently attracted significant research interest because of their superior performance at room temperature as human-compatible thermoelectric constituents. We examined the synthesis of Yb3Ge5 thin films and assessed their thermoelectric properties, considering the exceptional ability of Yb as a heavy metal to scatter phonons. The components of the resulting thin film were strongly dependent on the Yb/Ge deposition ratio and the subsequent annealing temperature. An increase in the Yb content augmented the formation of Yb2O3, whereas an increase in the Ge content facilitated the formation of Ge crystals. These trends were more evident at higher annealing temperatures. By controlling the YbGe composition, a power factor of 1470 µW m−1 K−2 was obtained at an annealing temperature of 700 °C, along with a low thermal conductivity of 3.1 W m−1 K−1. Machine-learning-facilitated data analysis revealed that the high power factor originated from Yb3Ge5. Notably, the power factor reached 1370 µW m−1 K−2 even at a temperature of 500 °C, causing the expansion of heat-resistant plastic films. Thus, we established the impressive potential of Yb3Ge5 as a suitable material for eco-friendly thin-film thermoelectric generators.