bluuebunny/crossref_metadata_2025 huggingface dataset:
Between the Russian Village and the Industrialization: an Essay About the Works of A. I. Zavalishin
Authors:   Ural Federal University, Podlubnova Yulia S. ,   Institute of History and Archeology Ural Branch of the Russian Academy of Sciences
Published: March 2022

The article offers an overview of the work of the writer and playwright Alexander Ivanovich Zavalishin starting with his texts of the 1910s and ending with the book “The Budenny’s hut” (1938). The feuilletons of the 1920s published in the newspaper “The Soviet Truth” (Chelyabinsk) are considered for the first time. The evolution of A. I. Zavalishin is outlined. It associated with the formation of the Ural writer within “newspaper literature” and further steps towards the success of the Soviet author. He did not only portray the current everyday life but also promote the values that were actualized by Soviet rhetoric and precisely in those forms that were approved and were in demand by the time. In the 1920s he created satire and scenes from village life, comedies and revolutionary dramas, in the 1930s wrote epic production dramas, a book about the heroics of the Civil War. The movement of A. I. Zavalishin from social literature of the 1920s to socialist realism of the 1930s is shown.
About One Source of the Plot of Lidya Charskaya’s “Sibirochka”
Authors:   Moscow State University named after M. V. Lomonosov, Puriaeva Nadezhda N. ,   Shenzhen MSU-BIT University
Published: March 2022

The hypothesis is presented in the following study according to which one of the plot sources of Lidya Charskaya’s story “Sibirochka” is the story of Parasha Lupolova. Charskaya reproduces the main elements of the so­called “parasha’s plot”, which served as the basis for a number of short stories, both authored and anonymous, throughout the XIX century, but adapts it for children’s readership. In her story, Charskaya offers a variant of a teenage girl role model. Unlike her predecessors, who turned to the “parasha’s plot”, the writer focuses special attention on the main character. Through her, Charskaya introduces a rather unusual for the beginning of the XX century concept of cultural and ethnic tolerance.
What is more important — technologies or meanings? Reflections on Convergent Journalism
Authors:   Ural Federal University, Antoshin Aleksei V.
Published: March 2022

The article is a review of the monograph by V. F. Oleshko and E. V. Oleshko, published by the Ural University Press in 2020. The authors’ contribution to the development of the concept of convergent journalism is substantiated. It is proved that the monograph under review provides an in­depth analysis of the role of the media in the digital age.
Computational Benefits of Intermediate Rewards for Goal-Reaching Policy Learning
Authors: Zhai Yuexiang , Baek Christina , Zhou Zhengyuan , Jiao Jiantao , Ma Yi
Published: March 2022

Many goal-reaching reinforcement learning (RL) tasks have empirically verified that rewarding the agent on subgoals improves convergence speed and practical performance. We attempt to provide a theoretical framework to quantify the computational benefits of rewarding the completion of subgoals, in terms of the number of synchronous value iterations. In particular, we consider subgoals as one-way intermediate states, which can only be visited once per episode and propose two settings that consider these one-way intermediate states: the one-way single-path (OWSP) and the one-way multi-path (OWMP) settings. In both OWSP and OWMP settings, we demonstrate that adding intermediate rewards to subgoals is more computationally efficient than only rewarding the agent once it completes the goal of reaching a terminal state. We also reveal a trade-off between computational complexity and the pursuit of the shortest path in the OWMP setting: adding intermediate rewards significantly reduces the computational complexity of reaching the goal but the agent may not find the shortest path, whereas with sparse terminal rewards, the agent finds the shortest path at a significantly higher computational cost. We also corroborate our theoretical results with extensive experiments on the MiniGrid environments using Q-learning and some popular deep RL algorithms.
Modern global oil market under stress: system dynamics and scenarios
Authors: Madhavi Madhu , Nuttall William J.
Published: March 2022

Modelling techniques developed 40 years ago to gain insight into the issues of energy supply security remain powerful even as the focus of energy technology policy analysis has shifted to consider new problems and to use research methods more closely linked to pressing environmental challenges. Dynamic modelling continues to be of merit and indeed it has the potential to provide helpful perspectives on contemporary problems such as climate change and the transition to net-zero greenhouse gas emissions. This study seeks to help revive system dynamics (SD) modelling of the global oil market. The SD-based analysis used in this paper facilitates a rational representation of physical stocks and flows as well as causal linkages that drive decision making in the global oil system. The use of SD provides insights (intuitive and counter-intuitive) into the macro-level non-linear dynamics of global oil exchanges and permits assessment of the potential impacts of future changes in system behaviour. The model exhibits damped oscillations in oil prices, broadly consistent with real market behaviours. The results further illustrate the resilience of market dynamics in the phase of extreme supply-side shocks and reveal the ability of SD to simulate and model such effects even beyond the point of market failure.
Proposed novel bond-slip model for geocell reinforcement under pull-out loading condition
Authors: Isik Adem , Anil Ozgur , Gurbuz Ayhan
Published: March 2022

An analysis of a novel bond-slip model for geocell reinforcement in cohesionless soils was established in terms of bond stresses and displacements to evaluate the behaviour of geocell-reinforced soil structures. In this study, the bond-slip behaviour of geocell-reinforced cohesionless soils under different normal and interfacial shear stresses was investigated using a total of 55 pull-out tests on geocell reinforcements of different size and stiffness. The results obtained for load–displacement behaviour of the 55 pull-out tests on the geocell reinforcements in cohesionless soil were converted to bond stress–displacement graphs. Overall, it was found that the bond stress–displacement parameters depend significantly on the size and stiffness of the geocell reinforcement and the applied vertical stress.
A laboratory characterisation of the response of intact chalk to cyclic loading
Authors: Ahmadi-Naghadeh Reza , Liu Tingfa , Vinck Ken , Jardine Richard J. , Kontoe Stavroula , Byrne Byron W. , Mcadam Ross A.
Published: March 2022

This paper reports the cyclic behaviour of chalk, which has yet to be studied comprehensively. Multiple undrained high-resolution cyclic triaxial experiments on low- to medium-density intact chalk, along with index and monotonic reference tests, define the conditions under which either thousands of cycles could be applied without any deleterious effect, or failure could be provoked under specified numbers of cycles. Intact chalk's response is shown to differ from that of most saturated soils tested under comparable conditions. While chalk can be reduced to putty by severe two-way displacement-controlled cycling, its behaviour proved stable and nearly linear visco-elastic over much of the one-way, stress-controlled loading space examined, with stiffness improving over thousands of cycles, without loss of undrained shear strength. However, in cases where cyclic failure occurred, the specimens showed little sign of cyclic damage before cracking and movements on discontinuities led to sharp pore pressure reductions, non-uniform displacements and the onset of brittle collapse. Chalk's behaviour resembles the fatigue response of metals, concretes and rocks, where micro-shearing or cracking initiates on imperfections that generate stress concentrations; the experiments identify the key features that must be captured in any representative cyclic loading model.
An experimental investigation into the behaviour of destructured chalk under cyclic loading
Authors: Liu Tingfa , Ahmadi-Naghadeh Reza , Vinck Ken , Jardine Richard J. , Kontoe Stavroula , Buckley Róisín M. , Byrne Byron W.
Published: March 2022

Low-to-medium-density chalk can be destructured to soft putty by high-pressure compression, dynamic impact or large-strain repetitive shearing. These process all occur during pile driving and affect subsequent static and cyclic load-carrying capacities. This paper reports undrained triaxial experiments on destructured chalk, which show distinctly time-dependent behaviour as well as highly non-linear stiffness, well-defined phase transformation and stable ultimate critical states under monotonic loading. The chalk's response to high-level undrained cyclic loading invokes both contractive and dilative phases that lead to pore pressure build-up, leftward effective stress path drift, permanent strain accumulation, cyclic stiffness losses and increasing damping ratios that resemble those of silts. These outcomes are relatively insensitive to consolidation pressures and are distinctly different to those of the parent intact chalk. The maximum number of cycles that can be sustained under given combinations of mean and cyclic stresses are expressed in an interactive stress diagram which also identifies conditions under which cycling has no deleterious effect. Empirical correlations are proposed to predict the number of cycles to failure and mean effective stress drift trends under the most critical cyclic conditions. Specimens that survive long-term cycling present higher post-cyclic stiffnesses and shear strengths than equivalent ‘virgin’ specimens.
Retrospective Analysis of Patients with Percutaneous Dilatational Tracheostomy in Intensive Care Unit
Authors: KOCAYİGİT Havva , ÖZMEN SÜNER Kezban , PEKŞEN Özge , KIZILIŞIK Halil , TOMAK Yakup
Published: March 2022

INTRODUCTION: Tracheostomy is a method frequently applied in intensive care units with the indication of prolonged intubation. [1] Our aim in this study is to retrospectively analyze the percutaneous dilatational tracheostomy (PDT) cases performed in our clinic within 1 year.

METHODS: It's analyzed the patients who underwent PDT in Sakarya Training and Research Hospital, Anesthesia Intensive Care Unit between January 2019 and December 2019. Each patient's age, gender, diagnosis of intensive care admission, use of anticoagulant drugs, and APACHE II score were recorded. Then, the day of tracheostomy procedure, complications, total intensive care unit stay, and the patient's discharge from the intensive care unit were evaluated.

RESULTS: A total of 79 patients were found to have undergone PDT. It was observed that the mean age of the patients was 66.56±17.83 and 48 (60.8%) were male. It was observed that 25(31.6%) of the patients were admitted to the intensive care unit with the diagnosis of postresuscitation syndrome, 17 (21.5%) cerebrovascular accident, and 15(19%) pneumonia. The mean APACHE II scores of the patients were 24.1±6.2, and 16(20.3%) patients were discharged. The median PDT procedure day was 19.5[12-30]. It was determined that only 2 of the patients had minor and 1 major and 3 (3.9%) patients did not develop any other complications apart from the bleeding related complication.

DISCUSSION AND CONCLUSION: In our study, although 66 (83.6%) of the patients who underwent PDT procedure received anticoagulant-antiaggregant treatment, postoperative bleeding rates were observed to be quite low in accordance with the literature.
Results of adjustable intragastric balloon use according to Body Mass Index values
Authors: TURHAN Veysel Barış , ÖZTÜRK Doğan , ŞAHİN Mutlu , KESKİN Müge , BULUŞ Hakan
Published: March 2022

Aim: In our study, it was aimed to compare the results of adjustable intragastric balloons in patients according to body mass index.

Material and Method: We recorded the data of 82 patients that we performed AIGB procedure in the last four years. During the initial implantation of the balloon, inflating was performed with 300-350 cc saline and methylene blue. Body mass index values and excess weight loss ratios of the patients at the time of the balloon removal were noted. Patients' complaints and complications arising after balloon application or additional inflation were reported.

Results: It was determined that there was a statistically significant decrease between weight, BMI, and EWL values measured at the 4th, 8th, and 12th months after the first application was performed (p
The Effect of Epileptic Seizure Occurring After Intracranial Hemorrhages on Early Mortality
Authors: ÇAKIR Adem , BORA Ejder Saylav
Published: March 2022

Introduction: Intracranial hemorrhages (ICH) are at high risk for long-term morbidity and morbidity in terms of complications such as epilepsy. In our study, we aimed to determine the effect of epileptic seizure seen after ICH on early mortality and to provide information to the literature.

Methods: My study was done retrospectively. A total of 238 patients with a confirmed diagnosis of ICH who met the inclusion criteria were included in the study. In the classification of the seizure as early and late; early seizure up to the 14th day after bleeding; Seizures observed on the 14th day and above were classified as late seizures.

Results: In the demographic data There was no significant difference between the groups in terms of age. Seizure + 57.7% of cases were male; seizure – 52.7% of the cases were male and the groups were not different in terms of gender. When the effect of seizure type on 30-day mortality was examined, it was observed that mortality was significantly higher in cases with late seizures.

Conclusions: We determined that the epileptic seizure seen after ICH has an effect on mortality. Therefore, it is necessary to be careful in terms of mortality in cases with seizures. Especially in cases with late seizures, mortality is higher than in cases with early seizures, so it is necessary to be careful in terms of mortality in cases with late seizures. In addition, we found that the use of antiepileptic drugs did not affect mortality.
El asociacionismo difuso en el territorio
Authors: González Rivera Tatiana Vanessa
Published: March 2022

En el llamado Sector Social de la Economía en México a pesar de reconocer, a nivel constitucional y en su ley reglamentaria, diferentes formas de expresión; identificamos esfuerzos académicos y normativos enfocados estrictamente en las cooperativas. Este estudio se presenta como un significativo aporte que se decanta por el análisis de otras figuras asociativas de la Economía Social y Solidaria, exponiendo sus características más importantes y ventajas. Por otro lado, atendiendo a los acercamientos que hemos tenido con grupos y colectivos del sector; a partir del Proyecto “Nodess Morelos Solidario y Cooperativo” avalado por el Instituto de Economía Social del gobierno de México y que tiene como propósito impulsar ecosistemas de Economía Social y Solidaria en el país; identificamos un asociacionismo difuso a partir de la convergencia de experiencias emergentes y en resistencia que deambulan entre la formalidad e informalidad; por ende, el análisis procura también exponer este panorama y las razones esgrimidas por algunas de estas experiencias lo que nos permite derivar en sugerencias que pueden coadyuvar en la visibilidad y fomento del sector.
Experiência de uma universidade pública na produção de tecnologias para a proteção de trabalhadores na pandemia da COVID-19
Authors: Da Silva Santana Thiago , Pereira Portela Pollyana , Ariane Cedraz Morais Ariane , Emanuelle Peixoto de Souza Karine , Antonio Morais Marques Jeidson , Santa Bárbara da Silva Silvone , Souza de Santana Carvalho Evanilda , Da Silva Santos Passos Silvia
Published: March 2022

OBJETIVO: descrever a experiência de produção e distribuição de equipamento de proteção individual do tipo face shiled no âmbito do projeto UEFS-PROVIDAS. MÉTODOS E MATERIAIS: Relato de experiência, com participação de docentes e voluntários vinculados à Universidade Estadual de Feira de Santana, Bahia, Brasil, entre março a maio de 2020 em três etapas: planejamento, construção da proposta e levantamento de recursos; execução, com operacionalização da proposta; distribuição dos protetores faciais. RESULTADOS: A experiência na produção de tecnologias para a proteção de trabalhadores na pandemia da COVID-19 ocorreu em etapas. Sua execução possibilitou a produção de 6227 (seis mil e duzentos e vinte e sete) protetores faciais, beneficiando mais de 6000 (seis mil) trabalhadores que atuaram na linha de frente da pandemia da COVID-19 em 90 instituições de saúde. CONCLUSÃO: Foi possível descrever a experiência de produção e distribuição de equipamentos de proteção individual do tipo face shield. O projeto alcançou trabalhadores da saúde na segunda maior cidade da Bahia e sua microrregião fortalecendo a indissociável articulação dos saberes científicos produzidos na universidade atendendo às demandas da sociedade em tempos de pandemia para a redução da vulnerabilidade dos trabalhadores.
Pengaruh Penggunaan Metode Cooperative Integrated Reading and Composition (CIRC) terhadap Keterampilan Literasi Informasi ditinjau dari Hasil Belajar Sejarah Siswa
Authors: Samsiah Ila , Kusmarni Yani
Published: March 2022

This research was motivated by the low information literacy skills of students. This can be seen from the low skills of students in finding, processing, and presenting information. These skills can be seen through learning outcomes, because learning outcomes are a measure of the success of the learning process. Therefore, this study entitled "The Effect of Using the Cooperative Integrated Reading and Composition (CIRC) Method on Information Literacy Skills in terms of Student Learning Outcomes in History Learning (Quasi Experimental Research at Class X SMA Negeri 9 Bandung). The CIRC method is used in the experimental class by dividing students into small groups, which then each finding, processing, and presenting information, as well as making answers to problems. This study was conducted to examine the effect of using the Cooperative Integrated Reading and Composition (CIRC) method on information literacy skills in terms of student learning outcomes in history learning. The method used in this research is a quasi-experimental method with one group time series design. The research was conducted at SMA Negeri 9 Bandung. The instrument used to obtain data in the study was a written test in the form of multiple choice questions and a questionnaire. Based on the data obtained from the results of the calculation of the hypothesis test, the Sig. 0.004 0.05 so that Ho is rejected and Ha is accepted so that there is an effect of using the CIRC method on information literacy skills both for groups of students who have information literacy skills "Good", "Good Enough" and “Not Good”. Meanwhile, the results of the pretest and postest statistical tests show that there were differences in learning outcomes for groups of students who had information literacy skill “Good”, “Good Enough, or “Not Good before and after using the CIRC method. This can be seen from the increase in the average pretest-postest score and the gain index of each experimental class.
Pasundan People's Party in Pasundan Countries 1947-1950
Authors: Pangersa Sugih Rachmat
Published: March 2022

This research entitled "The Gait of Pasundan People's Party in Pasundan State from 1947-1950". The main problem in this research is to get to know "How was the gait of the Pasundan people's party in the Pasundan state from 1947-1950?". The method used in this research is the historical method. Based on the results of this research, it can be explained about the background of the formation of the Pasundan People's Party, the role of the founding figures of the Pasundan People's Party and the actions of the Pasundan People's Party in the Pasundan State government. The author concluded that the formation of Patai Rakyat Pasundan was motivated by Suria Kartalegawa's desire to lead West Java and was assisted by the Dutch who also wanted to form a Federal State in Indonesia. Suria Kartalegawa as a founding figure played an important role in the formation of the Pasundan People's Party which later declared the Pasundan State. The activities of the Pasundan People's Party in the government of the Pasundan State which divided into two, the first one is the Pasundan State declared by Suria Kartalegawa and second one is the Pasundan State as a result of the West Java Conference. Suria Kartalegawa's version of the Pasundan State did not last long due to the lack of support from several elements of society, both from figures or the West Java community itself and was considered a counter-revolutionary movement. Then the Pasundan version of the West Java Conference led by Wiranatakusumah V produced three West Java conferences, in this period Suria Kartalegawa and his Pasundan People's Party were more active in the Pasundan State Parliament with stand more in the opposition side. The Pasundan People's Party fainted and disbanded itself following the disbandment of the Pasudan State in 1950 and the arrest of Suria Kartalegawa, and then West Java again became part of the Republic of Indonesia.
Meningkatkan Keterampilan Literasi Informasi dalam Pembelajaran Sejarah Menggunakan Metode Double Loop Problem Solving (DLPS)
Authors: Yulianti Laili Hesti , Winarti Murdiyah
Published: March 2022

Information literacy skills in history learning are important skills to be developed. This research is motivated by the low information literacy skills of students in learning history. These indications can be seen from the ability to analyze the connectedness of historical events and the ability to process student information. Based on these problems, the researchers formulated several problems that were taken in the study including: first, how to plan history learning using the Double Loop Problem Solving (DLPS) method through E-Learning. Second, how to apply history learning using the Double Loop Problem Solving (DLPS) method through E-Learning. Third, how to improve information literacy skills using the Double Loop Problem Solving (DLPS) method in learning history through E-Learning. [F1] Fourth, How to overcome obstacles in using the Double Loop Problem Solving (DLPS) method in history learning through E-Learning. This study aims to improve students' information literacy skills in learning history. This study uses the research design of Kemmis and McTaggart which includes planning, implementation, observation, and reflection. The researched aspects of information literacy skills are recognizing needed information, accessing relevant information, selecting and comparing information from different sources, evaluating appropriate information, organizing and using information efficiently, combining and constructing information into knowledge. new, and communicating and reflecting information. Based on the results of research conducted, the use of Double Loop Problem Solving (DLPS) can improve students' information literacy skills in learning history. In the first cycle the average percentage is 50.4%, the second cycle is 60%, and the third cycle is 82.8%.
Peran Media Animasi Untuk Meningkatkan Kemampuan Historical Imagination Siswa Dalam Pembelajaran Sejarah
Authors: Wahyudi Ali
Published: March 2022

Penelitian ini berjudul Penggunaan Media Animasi Untuk Meningkatkan Kemampuan Historical Imagination Siswa Dalam Pembelajaran Sejarah (Penelitian Tindakan Kelas di Kelas X IPS 3). Hal Tersebut dilatar belakangi oleh rendahnya imajinasi kesejarahan siswa yang terlihat dari proses pembelajaran siswa yang kurang dapat mengeksplorasi materi lebih dalam. Untuk meningkatkan kemampuan historical imagination tersebut peneliti bantu dengan menggunakan media animasi. Penelitian ini menggunakan metode Penelitian Tindakan Kelas model Kemmis dan Mc Taggart yang terdiri dari empat tahapan yakni perencanaan (plan), tindakan (act), observasi (observation), dan refleksi (Reflection). Berdasarkan pada hasil penelitian dapat dijelaskan bahwa pada siklus kesatu mulai terlihat sedikit perubahan pada siswa ketika tindakan pertama kali dilakukan terutama pada indikator historical imagination akan tetapi waktunya terpotong oleh kegiatan PTS. Siklus kedua mempunyai lebih banyak waktu, namun sayangnya harus mengalami penurunan dikarenakan siswa tampak bosan dengan tindakan yang dilakukan.Pada siklusketiga kembali mengalami peningkatan dengan setelah kendala-kendala yang dialami pada siklus sebelumnya berhasil diminimalisir pada tindakan ini. Simpulan media animasi memudahkan siswa untuk melakukan kembali, menyisipkan, dan bertanya mengenai materi yang disajikan di setiap tindakannya.
Knowledge and Attitude of Universiti Kebangsaan Malaysia (UKM) Medical Students on Forest Bathing
Authors: Ignatius Aaron , Lynn Teo Sze , Aiman Hazimin Wan Muhammad , Ahmad Fahninazirah , Shida Aeinaa , Hod Rafidah , Mohd Yusoff Hanizah , Mohamed Ahmad Fariz , Hod Rozita
Published: March 2022

ABSTRACT Background and aims: Forest bathing or Shinrin-Yoku is a practice of being mindful of nature and it offers multiple health benefits in both physiological and psychological factors. This study aimed to determine the knowledge and attitude of Universiti Kebangsaan Malaysia (UKM) medical students towards forest bathing and its relationship with the sociodemographic factors. Materials and methods: A total of 165 UKM medical students were recruited using proportionate random sampling. The subjects were then categorized based on the academic year (Year 1 - Year 5). Exclusion criteria includes those who deferred their academic year and/or who were hospitalized. A questionnaire was given via a google form consisting of sociodemographic data details and 15 questions for each knowledge and attitude on forest bathing. Results: The prevalence of good knowledge and good attitude of UKM medical students towards forest bathing were 64.2% (n=106) and 50.9% (n=84) respectively. Female medical students had a good knowledge (n=63, 73.3%) and good attitude (n=52, 60.5%) compared to male medical students’ knowledge (n=43, 54.4%) and attitude (n=32, 10.5%) leading to a p-value of 0.012 and p-value of 0.010. Otherwise, other sociodemographic factors including race, level of medical year and level of lifestyle did not affect participants’ knowledge and attitude on forest bathing. Conclusion: Majority of UKM medical students have a higher prevalence of good knowledge compared to good attitude on forest bathing. Therefore, intervention is recommended especially towards male medical students as forest bathing has enough evidence as preventive medicine. Keywords: Shinrin-yoku, Preventive medicine, Nature therapy, Malaysia.
The impact of diabetes mellitus on levels of sex hormones and their receptors in tumor tissues in female rats with Guerin’s carcinoma
Authors: Frantsiyants E. M. , Bandovkina V. A. , Kaplieva I. V. , Surikova E. I. , Pogorelova Yu. A. , Cheryarina N. D. , Kotieva I. M. , Morozova M. I. , Shikhlyarova A. I.
Published: March 2022

Purpose of the study. Analysis of the effect of DM on levels of sex hormones and their receptors in tumor and perifocal tissues in outbred white female rats.

Materials and methods. Outbred white female rats were divided into 2 groups, 18 rats each: control group – with transplantable Guerin’s carcinoma, main group – with transplantable Guerin’s carcinoma growing in presence of DM. DM was reproduces in animals by the single intraperitoneal alloxan injection (150 mg/kg body weight). Animals were killed after 10 days of the tumor growth. Levels of hormones (estradiol, testosterone, progesterone and prolactin) and their receptors (RЕα, RЕβ, RA and RP4) were measured by ELISA in tumor and perifocal tissues in animals of the control and main groups.

Results. Female rats with Guerin’s carcinoma growing in presence of DM showed an increase in glucose in tumor and perifocal tissues by 1.8 times (р < 0.05) and 7.6 times, respectively, compared to the levels in the control group. Levels of E2 were increased, respectively, by 2.4 and 9.5 times; P4 – by 2.1 and 3.0 times; PRL – by 2.7 and 4.4 times. T was increased in perifocal tissues by 2.2 times and was unchanged in tumor tissues. RЕα and RP4 were elevated by 3.9 and 3.0 times, respectively, only in tumor tissues, and RA by 3.9 times only in perifocal tissues. The REα/RЕβ ratio was increased only in the tumor by 3.2 times. The Е2/RЕβ ratio was increased in tumor and perifocal tissues by 2.0 and 9.6 times, respectively. The T/RA ratio was decreased in the tumor and its perifocal area by 1.4 (р < 0.05) and 2.0 times, respectively. The opposite changes were observed in the Е2/RЕα and P4/RP4 ratios: a decrease in the tumor by 1.6 and 1.4 times, respectively (р < 0.05), and an increase in the perifocal area by 9.8 and 2.5 times, respectively.

Conclusion. Female rats with Guerin’s carcinoma growing in presence of DM demonstrated local hyperglycemia, changes in the levels of sex steroids and a misbalance in their receptors in tumor and perifocal tissues causing active metastasis and reduced average survival of animals.
Analysis of Gene Expression Omnibus high-throughput sequencing data for the determination of microribonucleic acids in the blood plasma of patients with glioblastomas
Authors: Pushkin A. A. , Gvaldin D. Yu. , Timoshkina N. N. , Rostorguev E. E. , Vladimirova L. Yu. , Dzenkova E. A.
Published: March 2022

Purpose of the study. This work is devoted to the study of blood plasma miRNA patterns in blood plasma using high-throughput sequencing of the Omnibus Gene Expression base and the search for candidate miRNA molecules for the development of a minimally invasive diagnostic panel.

Materials and methods. Basing on the open dataset of Omnibus Expression of the NCBI GSE150956 Gene, groups of samples with glioblastoma and conventionally healthy donors were formed. For each sample, information on the levels of miRNA expression was extracted. Determination of significant miRNAs using machine learning algorithms of the R 4.0.4 project. For significant miRNAs, target genes have been performed, an analysis of the improvement of functional characteristics and interactome analysis of target genes of miRNA were performed.

Results. The study analyzed the data of 131 samples, where 35 samples with glioblastoma and 96 samples of the conditionally healthy group. Differential expression data were obtained for 945 miRNA. Two panels were obtained using machine learning methods, common miRNA – hsa-miR 3180, hsa-miR 3180-3p, hsa-miR 6782-5p, hsa-miR 182-5p, hsa-miR 133b and hsa-miR 670-3p. For significant miRNAs, information was obtained on experimentally confirmed target genes, a gene ontology demonstrating their participation in enzyme binding, participation in the regulation of primary cellular metabolic processes, and the development of glioblastomas and cancer in general.

Conclusion. As a result of layer-by-layer filtering and application of machine learning algorithms, significant miRNAs were identified that are candidates for a diagnostic panel of a minimally invasive method of high-grade glial tumors.
Nesting of fieldfare Turdus pilaris (Linnaeus, 1758) (Aves, Passeriformes) in floodplain habitats of the Abakan River basin (South Minusinsk basin)
Authors: Veysner Tatyana Viktorovna , Zlotnikova Tamara Viktorovna
Published: March 2022

This paper presents the results of long-term observations of the fieldfare breeding biology in the South Minusinsk basin. The observations were carried out at two sites in floodplain habitats of the Abakan River basin. Comparisons were made with the indicators of the breeding biology of the species in the North-Minusinsk basin, which were published. The fieldfare builds nests on all kinds of woody plants that are found in the floodplain. The time of Turdus pilaris reproduction beginning in the steppe basin varied from the 20th of April to the first five days of May. Differences in the breeding periods of fieldfare in populations from different altitude-belt complexes (steppe and forest-steppe) were revealed. There is a difference in the height of nests on woody plants, depending on the architectonics of the crown, and in areas with varying degrees of concern. Dimensional characteristics of nests and eggs are given. High intrapopulation variability of egg size was noted. The coefficient of variation for the larger and for the smaller diameter was 1113%. The full clutch consisted of 46 eggs. The average clutch size was 4,95,2 eggs. Differences in the average size of the masonry on different territories were not revealed. The success rate of nesting in 2021 was high (5072%).
The isotopic composition of hair among the population in the Vologda Region depending on the conditions of living and nutrition
Authors: Ivanova Elena Sergeevna , Rumiantseva Olga Yurievna , Zavertkina Anastasia Sergeevna , Bueva Anastasia Evgenievna , Elizarova Anna Sergeevna
Published: March 2022

Isotope mass spectrometry methods are used to study changes in the isotopic composition of organisms in the food chain called trophic fractionation. In particular, with the help of isotope analysis of tissues, it is possible to determine the type of nutrition and possible place of residence of a person, which helps in solving the tasks of forensic examination. In this study, the isotopic composition C and ⁵N in the hair of residents of the industrial city of Cherepovets and the Kirillovsky District of the Vologda Region, remote from industrial sources of pollution, was determined. The determination of the isotopic composition of hair was carried out on an isotope mass spectrometer Thermo-Finnigan Delta V Plus in the Ecological and Analytical Laboratory of Cherepovets State University. The average values of isotopes in the hair of the study participants are 20,86 (C) and 9,98 (⁵N). There are differences in the ratio of carbon and nitrogen isotopes in the hair of residents of Cherepovets and Kirillovsky District. There are not statistically significant differences in the isotopic composition of C and ⁵N in the hair of female and male. There are differences of ⁵N in the hair of people who consume different amounts of fish (people who consume fish more often have a higher ratio of ⁵N).
Species structure and pharmaceutical features of forest communities fungi in the Voronezh Region
Authors: Shtern Anastasia Maksimovna , Melkumov Gavriil Mikhailovich
Published: March 2022

The work is devoted to the study of the species structure and pharmaceutical features of forest communities fungi in the Voronezh Region. The mycological study revealed 171 species of fungi belonging to 2 divisions of Ascomycota and Basidiomycota, 7 classes, 19 orders, 58 families and 106 genera. Most of the species belong to the orders Agaricales (81 taxa), Russulales (23), Polyporales (21) and Boletales (19). Among the identified taxa of medicinal fungi, saprotrophs (85) and symbiotrophs (53) predominate. The overwhelming number of mushroom species belongs to edible (92) and inedible (51) categories. 108 representatives of the mycobiota of the Voronezh Region can be used for the treatment of oncological diseases, 89 for the production of substances with antibacterial activity. To a lesser extent, fungi have antiviral activity (49), immunostimulating properties (36), anti-inflammatory action (28), antioxidant activity (22). Fruit bodies (158 taxa) and mycelium (22) are most often used as a source of release of useful substances. The identified species of fungi contain 23 types of toxins that lead to diseases of various etiologies, among which -amanitin, grismalin, ibo-tenic acid, cordinarin, muscarin, muscimol and phalloidin dominate (in 3 representatives).
Youth in the anti-religious propaganda discourse of the 1920s (based on materials from the Samara province)
Authors: Protasova Alina Vladimirovna
Published: March 2022

The cultural transformation of Russian society in the first decades after the October Revolution made significant changes in the spiritual sphere. Traditional religious beliefs had to be replaced by a new ideology. The citizens of the new state had to accept a new cultural code and everyday practices, discarding the previous pre-revolutionary traditions, including religious ones. The efforts of the authorities on this cultural transition were primarily directed at the younger generation of Soviet citizens. This research aims to study the participation and activities of young people in the framework of anti-religious propaganda of the 1920s, using the materials of the provincial center Samara province. This paper analyzes and compares anti-religious work carried out by Komsomol organizations and other associations among the younger generation, as well as identifies the general level of religiosity. The study of materials on the Samara province will allow us to consider this problem at the micro level, which will allow us to more fully reveal the history of the development of religion in the USSR. The findings of the research illustrate the contamination of processes. On the one hand, the direct participation of young people in the new anti-religious reality was observed, on the other hand, the young people themselves were experimental subjects in this cultural experiment. The combination of these roles gave rise to special forms of behavior among Soviet youth and pushed them to commit certain actions.
Participation of microbiologists Z.V. Ermolyeva and L.M. Yakobson in a scientific discussion about the fate of the production of Soviet cholera bacteriophages in 1967
Authors: Gorshenin Aleksandr Vladimirovich
Published: March 2022

Since the late 1920s in the USSR, along with many countries, there has been an interest in studying the phenomenon of bacteriophagy and its use in medicine. Bacteriophages are called bacterial viruses. Significant work on the study of bacteriophages and their use for medical purposes was carried out by Soviet microbiologists Zinaida Vissarionovna Ermolyeva and Lidiya Mikhailovna Yakobson. They paid especially great attention to the study of cholera bacteriophage, which during the Great Patriotic War helped prevent the cholera epidemic in frontline Stalingrad. In the 1940s due to the advent of the era of antibiotics with a wider range of applications, research interest in bacteriophages was waning. Nevertheless, in the prevention and treatment of a number of infectious diseases of bacterial origin, phage continued to be used in the following decades. In 1967, one of the countrys largest microbiologists sent an appeal to the Chief Sanitary Doctor of the USSR with a proposal to stop or reduce the production of cholera bacteriophage in the country. In this regard, a scientific discussion in which Z.V. Ermolyeva and L.M. Yakobson played an important role unfolded. Using the materials of the State Archive of the Russian Federation and the Russian State Archive of Economics, involving published scientific works on microbiology and medicine, an attempt is made to analyze this scientific discussion and establish its significance in the fate of the production of cholera bacteriophage in the USSR.
Tolerance development while teaching foreign languages for business communication
Authors: Gorlova Ekaterina Aleksandrovna , Gridneva Natalia Aleksandrovna , Doskovskaya Mariya Sergeevna , Zhuravleva Olga Vasilievna
Published: March 2022

The paper deals with the problem of tolerance development while teaching foreign languages for business communication. The urgency of the problem regarded is justified by the need of developing a person ready to a balanced and happy life in the modern multicultural society, as well as by the significance of tolerance as a professionally important quality and as a factor of creating a psychologically safe and comfortable environment for educational process. The great potential of the course Business foreign language for tolerance development is explained through opportunities to use the axiological approach and the well-known idea of the dialog of cultures, through extensive communication practice, as well as through opportunities for familiarizing with the ethics of business communication always based on the respectful attitude to the partner. The process of tolerance development breaks into three main steps in accordance to the three components of the traditional psychological model of tolerance: 1) giving information about the tolerance and its social importance (cognitional component), 2) development of values-based attitude towards the tolerance (emotional-axiological component), 3) use of the newly acquired value system in communication (behavioral component). The thematic content of the course and the most effective teaching methods are regarded.
Superstitiousness of university students majoring in arts and its role in their professional development
Authors: Gorodetskaya Inna Mikhailovna , Khatsrinova Olga Yurievna , Petrova Anna Vladimirovna , Abitov Ildar Ravilevich
Published: March 2022

The study addresses peculiarities of superstitiousness and paranormal beliefs of students majoring in Arts (creative type of professions) and its role in their professional development. Superstitiousness is a rather wide-spread phenomenon among different professional groups. Besides there is scientific evidence that students are a socio-demographic group with high level of superstitiousness. There exist two general points of view on superstitiousness as a psychological phenomenon: negative and coping. Creative activity in general and creative professions in particular are characterized by high uncertainty and unpredictability of its outcomes, therefore it was logic to suppose that future creative professionals would be highly superstitious. Besides constant search for innovative solutions and Art itself focuses on irrational aspects of being. Empiric study however showed average and low level of superstitiousness among Arts students, but significant correlations between superstitiousness, paranormal beliefs and personality traits. Differences between various creative professions were also found. The findings may be used for the future studies and applied in the educational practice.
Peculiarities of the civil-legal aspect of students’ environmental consciousness: the problem statement
Authors: Nikitin Nikolai Aleksandrovich
Published: March 2022

The paper deals with a pilot study that has been conducted by the author. It is a part of the study of the peculiarities of the civil-legal aspect of students environmental consciousness. Theoretical prerequisites for studying ecological consciousness, civil law foundations of social interaction and peculiarities of civil identity have been determined. The study has been conducted at Samara State University of Social Sciences and Education with a help of a sociological survey using online questionnaires and the functionality of Google Forms. 269 students from various fields of training have taken part in this survey. The results provided an opportunity to assess the starting positions of the study and draw some conclusions about respondents moods and assessments regarding questions of interest. In general, the results obtained indicate a negative assessment of the environmental situation in the country, as well as in the world, the actions of the State to preserve environmental balance are not sufficiently assessed. The individual activity of students aimed at maintaining an ecological lifestyle is characteristic of almost half of respondents, while the knowledge about the main international environmental agreements and the largest natural-scientific concepts of the environment is also not familiar to more than half of respondents. The obtained results made it possible to determine the further direction of research with the involvement of specialists in the field of sociology, social studies, ecology, pedagogy and psychology in solving the set tasks.
Communication activity of a digital society teacher
Authors: Strekalova Natalya Borisovna
Published: March 2022

The paper examines the stages of society informatization (automation, informatization and digitalization) in historical retrospect and their impact on education. It also defines changes in the activity of a teacher in a digital society and education digitalization: specifics of the teachers activity in a digital society due to changes in the object (virtual learner), subject (digitized data, digital traces of the students educational activities) and tools of activity (digital technologies and platforms, video conferencing, information processing technologies); the peculiarity of the teachers activity due to the teachers remote interaction with students (online and offline communication); difficulties and problems of the teachers communication interaction with students. The theoretical conclusions are supported by the results of a pilot study in which teachers of educational institutions of higher and secondary vocational education participated. The empirical data obtained revealed difficulties affecting the quality of knowledge transfer in online and offline communications, problems of information flow management, as well as a tendency to reduce problems related to compliance with the rules of network ethics.
The Unique Role of Time in Autobiographical Memory Consolidation
Authors:   , McWilliams Kellie , Lee Nancy Raitano
Published: March 2022

One of the enduring mysteries of cognitive neuroscience is the representation of time as an aspect of memory. Time is an essential feature of autobiographical memory consolidation within the brain. When brain lesions result in retrograde amnesia, memories are lost in a time ordered fashion - from the time of the lesion in the present back in time toward the past. Memories also recover from the past toward the present. Time is a major construct ordering memory search. Memories form the basis for structuring subjective time constructions. The aim of this research project was to examine the unique role of time in the consolidation and retrieval of autobiographical episodic memories. The project utilized participant supplied photos representing four temporally discrete autobiographical memories as recall cues in a functional MRI paradigm. Participants were 20 +/- 6 months years of age. The results supported a decrease in consolidation processes over time with recall for older memories showing less medial temporal lobe activation and more neocortical activation for more recent memories. There was also greater connectivity between and within neocortical association areas and the medial temporal lobe for older versus recent memories. This study contributes to the literature on the organization of episodic memory storage within the brain. Understanding the organization of episodic memories can advance the academic study of memory by providing a common framework for memory progression and impact the clinical care of patients with memory disorders by providing therapeutic targets for recovery.