bluuebunny/crossref_metadata_2025 huggingface dataset:
To Analyse the Effectiveness of Remote Fetal Heart Rate Monitoring Based on Internet in Late Pregnancy During the COVID-19 Pandemic
Authors: Zhou Shuguang , Jin Qinqin , Jiang Xiya , Bingbing Wang , Yao Hui , Yang Yinting , Ying Jie , Tian Lu , Zhang Weiyu , Zhu Yuting , Chen Guo , Cao Wujun
Published: May 2022

AIM. To evaluate the consistency of pregnancy outcomes and related clinical monitoring indicators in high and low risk group under two different monitoring methods during COVID-19 pandemic.Methods. The study was conducted among 765 primipara after a gestational age 32 weeks in Anhui Medical University Affiliated Maternity and Child Healthcare Hospital (January 2020 —December 2020). The subjects were randomly divided into two groups by their wishes.The control group (n=384) received traditional fetal heart monitoring, and the experimental group (n=381) received remote fetal heart monitoring. To evaluate the consistency of pregnancy outcomes and related clinical monitoring indicators in different groups under two different monitoring methods.Results. It was found that there was no statistically significant difference between the two groups in terms of pregnancy outcome (including mode of delivery, postpartum hemorrhage, etc.) and neonatal outcome (including preterm birth rate, neonatal weight, neonatal Apgar score, etc.) (p>0.05). It should also be noted that the difference in the scores of HADS-A and HADS-D between the two groups was statistically significant (p<0.05) and the EPDS score results were statistically different. Meanwhile, there was a statistically significant difference in the total cost of labor and delivery between two groups (p<0.05) and total time spent on labor and delivery between the two groups (p<0.05).Conclusions. Remote Fetal Heart Rate Monitoring Based on Internet is an innovative, acceptable, and effective reduced-frequency prenatal examination model. Compared to routine prenatal examination, Remote Fetal Heart Rate Monitoring Based on Internet resulted in higher patient satisfaction and lower prenatal stress. Besides, Remote Fetal Heart Rate Monitoring Based on Internet compared with the traditional fetal heart monitoring does not affect the pregnancy outcomes of pregnant women with different high-risk factors, maternal accept degree is high, and to reduce the medical resources pressure. It is an effective and feasible way for self-monitoring of pregnancies in late pregnancy during the pandemic of COVID-19 and is worthy of clinical application.
A buffalo rumen-derived probiotic (SN-6) could effectively increase Simmental growth performance by regulating fecal microbiota and metabolism
Authors: Yang Shumin , Luo Ji , Chen Yingying , Wu Rui , Liu Huazhen , Zhou Zutao , Xiao Yuncai , Shi Deshi
Published: May 2022

Background: Microorganisms play a key role in rumen digestion which are often used as probiotics to promote growth in ruminants. However, it's unclear which bacteria play an important role and how they do it. This study focused on the growth-promoting effects of the buffalo-derived probiotic SN-6 and examined its effects on the fecal flora and metabolism in Simmental, analyzing the impact of altered intestinal flora on host metabolism to elucidate the underlying probiotic mechanisms.Results: Three bacterial strains, Bacillus pumilus (SN-3), Bacillus paralicheniformis (SN-6) and Bacillus altitudinis (SN-20) with multiple digestive enzymes secretion capability were isolated from the rumen of healthy Buffalo, SN-6 exhibited outstanding among the three strains. SN-6 secreted cellulase, laccase and amylase, and had potent inhibitory effects on Staphylococcus aureus ATCC25923 and Escherichia coli K99. In addition, SN-6 exhibited strong tolerance to artificial gastric juice, intestinal juice and high temperature. Antibiotic resistance test, virulence gene test and mouse toxicity test confirmed the safety of SN-6. SN-6 significantly increased the average daily weight gain of Simmental (p<0.01), and affects the fecal microbiota structure and fecal metabolomic patterns of Simmental. There was a remarkable difference in the β diversity of fecal microflora between SN-6 and control groups (p<0.05). Further, SN-6 significantly increased the abundance of Clostridium_sensu_stricto_1, Bifidobacterium, Blautia and Cellulolyticum and decreased the relative abundance of Monoglobus, norank_f_Ruminococcacea. Moreover, SN-6 feeding significantly enriched fecal metabolites to maintain intestinal homeostasis and strengthen intestinal barrier function (i.e., 3-Indoleacrylic acid, Kynurenic acid). Finally, the microbial and metabolic function analysis indicated that SN-6 would enhance amino acid metabolism (mainly tryptophan metabolism) and lipid metabolism pathways.Conclusions: SN-6 exerted beneficial effects by targeting the gut microbiota and host metabolism (mainly tryptophan metabolism). Our findings reveal the effect of SN-6 on Simmental microbiota and metabolism, and provide a new reference for the research on Bacillus regulating ruminant gut microbiota and metabolism.
A dual-domain image encryption algorithm based on a seven-dimensional hyperchaos and dynamic wavelet decomposition
Authors: Liang Zhongyue , Qin Qiuxia , Zhu Weiming , Zhou Changjun , Liu Shuang
Published: May 2022

In order to ensure the safe and reliable transmission of images on public channels, this paper proposes a dual-domain image encryption algorithm based on a seven-dimensional hyperchaos and dynamic wavelet decomposition. It is worth mentioning that the existing encryption algorithms generally use spatial encryption, which still has shortcomings in encryption security and execution efficiency. However, the combination of dynamic wavelet decomposition and scrambling and diffusion operations is adopted in our algorithm to realize the combination of spatial and frequency domain encryption. Compared with the existing algorithm, this not only ensures the security of the encryption algorithm, but also ensures the robustness and operating efficiency of the encryption, and at the same time reduces the risk of being attacked. First, divide the original image into blocks, use a random number sequence to control the block scrambling process, and generate a scrambling matrix; Then by calculating the Hamming distance related to the plaintext, dynamically selecting the wavelet type, performing wavelet decomposition, and generating a wavelet coefficient matrix; Re-input the plaintext image to the SHA-512 algorithm to generate the initial value of the seven-dimensional hyperchaos. The chaotic system generates the chaotic key matrix through iteration; Then the scrambling matrix is dynamically rotated, and then the Zigzag transform is used to generate the key matrix; Finally, the wavelet coefficient matrix, the chaotic key matrix, and the key matrix are subjected to bitwise XOR operation to realize the diffusion of pixel values and obtain the final encrypted image. Simulation experiments and performance analysis experiments can show that this algorithm can effectively encrypt and decrypt images, and has good encryption and decryption quality. And compared with existing encryption algorithms, it has better security, robustness, operational efficiency and the ability to resist various attacks.
Long-COVID post-viral chronic fatigue and affective symptoms are associated with oxidative damage, lowered antioxidant defenses and inflammation: a proof of concept and mechanism study.
Authors: Al-Hakeim Hussein Kadhem , Al-Rubaye Haneen Tahseen , Al-Hadrawi Dhurgham Shihab , Almulla Abbas F. , Maes Michael
Published: May 2022

The immune-inflammatory response during the acute phase of COVID-19, as assessed using peak body temperature (PBT) and peripheral oxygen saturation (SpO2), predicts the severity of chronic fatigue, depression and anxiety (“physio-affective”) symptoms three to four months later. The present study was performed to characterize whether the effects of SpO2 and PBT on the physio-affective phenome of Long COVID are mediated by immune, oxidative and nitrosative stress (IO&NS) pathways. This study assayed SpO2 and PBT during acute COVID-19, and C-reactive protein (CRP), malondialdehyde (MDA), protein carbonyls (PCs), myeloperoxidase (MPO), nitric oxide (NO), zinc, and glutathione peroxidase (Gpx) in 120 Long COVID individuals and 36 controls. Cluster analysis showed that 31.7% of the Long COVID patients had severe abnormalities in SpO2, body temperature, increased oxidative toxicity (OSTOX) and lowered antioxidant defenses (ANTIOX), and increased total Hamilton Depression (HAMD) and Anxiety (HAMA) and Fibromylagia-Fatigue (FF) scores. Around 60% of the variance in the physio-affective phenome of Long COVID (a factor extracted from HAMD, HAMA and FF scores) was explained by OSTOX/ANTIOX ratio, PBT and SpO2. Increased PBT predicted increased CRP and lowered ANTIOX and zinc levels, while lowered SpO2 predicted lowered Gpx and increased NO production. Both PBT and SpO2 strongly predict OSTOX/ATIOX during Long COVID. In conclusion, the impact of acute COVID-19 on the physio-affective symptoms of Long COVID is partly mediated by OSTOX/ANTIOX, especially lowered Gpx and zinc, increased MPO and NO production and lipid peroxidation-associated aldehyde formation. Post-viral physio-affective symptoms have an inflammatory origin and are partly mediated by neuro-oxidative toxicity.
Bio-Water Management Mechanisms to Inspire New Building Solutions.
Authors: tantawy amal
Published: May 2022

This research paper contributes to investigating the extent to which knowledge and mechanisms of biological water management can be explored to inspire new solutions for buildings and how biologically developed methods that can be used both to provide water and obtain it from the outer casings of buildings interacting with nature can be explored, and the research methodology is first carried out by examining various examples of organisms that have highlighted and demonstrated their natural success in the good management of For the water and work of a detailed analysis of the mechanisms of these organisms in the provision and management of water, ii detailed presentation and analysis of a set of global examples simulated to the environment, which has a precedent in the application of the concept (water management through an environmentally adapted outer shell), thirdly comes the applied study by proposing checklist models with proposed relative weights based on previous studies to measure the success of analytical examples in accomplishing the task of Namibia Hydrology Center ranked first with the highest percentage of use of naturally inspired water management functions, Namibia Hydrology Center ranked first with the highest percentage of use of naturally inspired water management functions, and the first (water collection) job was ranked first with the highest percentage of repetition in all study cases, while the job (water storage) was second with a percentage of 63% of repetition, and reached 100% of repetition in all study cases, while the job (water storage) was second with a percentage of 63% of repetition. The element (water collection) in the first place with the highest percentage reached 36% for the total size of all other elements of water functions, while the element (water storage) in the second place reached the highest percentage reached 23% relative to the total size of all elements of other aquatic functions, and the research reached many conclusions such as that the strategies of balance and biological water management in organisms in nature to provide innovative solutions for the design of the exterior of the building, especially in the third world countries new to this type of building where water management strategies are transferred from nature to the architectural design of the covers of external buildings, taking into account the choice of natural strategies suitable for each environment and place, as well as the research study reached that the strategies of living organisms in water management, whether synthetic or behavioral adaptation, boils down to a set of key biological functions, namely (acquisition of water - water transfer - storage of water- storage Water - preventing water loss - water purification).
Blueberry improves components of metabolic syndrome in animal studies: a systematic review and meta-analysis
Authors: Azari Hushyar , Morovati Ashti , Gargari Bahram Pourghassem , Sarbakhsh Parvin
Published: May 2022

Metabolic syndrome (MetS) is the co-occurrence of several interconnected metabolic disorders and its prevalence is rising in the world. We hypothesized that blueberry (BB) feeding will have positive effects on components of MetS according to studies which used animal subjects. A systematic search for the studies in Science Direct, Embase, Cochrane and PubMed databases was done. The Studies which investigated effects of BB on components of MetS in animal models were included. Of 1030 potentially relevant studies, after investigation, 28 animal studies remained for further investigation. Of these, 1 study was conducted using pigs, one study using hamsters, 15 studies using mice and 11 studies using rats. 18 studies were eligible for the meta-analysis, and others were included in systematic review. The meta-analysis was done by Comprehensive Meta-analysis Software.The results of the meta-analysis demonstrated no significant effect of blueberry feeding on body weight [p = 0.65 CI95%: (-3.029, 1.892)]. However, a statistically significant improvement of systolic blood pressure [p < 0.001, CI95%: (-0.916, -0.283)], diastolic blood pressure[p = 0.01, CI95%: (-1.10, -0.13)], triglycerides[p = 0.01, CI95%: (-1.018, -0.109], total cholesterol [p < 0.001 CI95%: (-1.693, -0.782)], low density lipoprotein(LDL) [p = 0.008, CI95%: (-2.182, -0.334)], high density lipoprotein(HDL) [p = 0.02, CI95%: (0.077, 1.057)], blood glucose [p < 0.001, CI95%:( -1.638, -0.623)] and insulin level [p < 0.001, CI95%: (-1.711, -0.688)] was reported. Conclusion: this study showed that blueberry can be effective in ameliorating some components of metabolic syndrome in animal models. There is a need to conduct more studies on this subject in humans.
Ensuring Food Security of Smallholder Farmers through Improving Productivity and Nutrition of Potato
Authors: Moreda Gedefa , Haile Ashenafi
Published: May 2022

In a time of extremely high population growth, loss of arable land and climate change effects, food security issue is becoming more and more important. Thus, improving the food security of smallholder farmer is a major concern particularly in developing country. In this regard potato is one of the important cash crops which contributes for food security and reduce poverty among smallholder farmers in the developing countries like Ethiopia. However, the productivity of the crops is constrained by the limitation of soil macronutrient. Therefore, this research was conducted with the aim to improve potato productivity through intensive and economical uses of soil macronutrients. A factorial combination of four soil macro nutrients and three potato varieties were used in a Randomized Complete Block Design with three replications. The result revealed that soil macronutrients and potato variety had significantly influenced on phenology and growth components. Interaction effects of soil macro-nutrients and variety had also significantly affected total and marketable tuber yield of potato. The marginal rate of return of 7,370% was obtained from the Wabi variety with the application of 200 kg ha − 1 soil macro-nutrients (NPS fertilizer). Therefore, growing the Wabi variety of potato at 200 kg/ha of soil macro-nutrients resulted in a high productivity and economic returns of the crop.
Lysine methylation promotes NFAT5 activation upon EGFR activation and predicts the efficacy of temozolomide
Authors: Wang Yuhong , Li Yatian , Zhang Binbin , Gao Zhenyue , Hu Ruxin , Wang Yuqing , Liu Chao , Zhang Xuebin , Yang Jingxuan , Mei Mei , Ren Yu , Li Min , Zhou Xuan
Published: May 2022

Temozolomide (TMZ) therapy exert limited clinical benefits in glioblastoma multiforme (GBM) patients with high EGFR activity, underscoring the need for effective combination therapy. Here, we show that tonicity-responsive enhancer binding protein (NFAT5) lysine methylation, is a determinant of TMZ response. Mechanistically, EGFR activation induces phosphorylated EZH2 (Ser21) binds to and triggers NFAT5 methylation at K668. Methylation prevents NFAT5 cytoplasm interaction with E3 ligase TRAF6, thus blocks TRAF6 induced K63-linked ubiquitination mediated NFAT5 lysosomal degradation and cytosol localization restriction, result in NFAT5 protein stabilization, nuclear accumulation and activation. Methylated NFAT5 leads to the upregulation of ITGB1, a transcriptional target of NFAT5, which is responsible for unfavorable TMZ response. Inhibition of NFAT5 K668 methylation improved TMZ efficacy in vivo. Notably, NFAT5 K668 methylation levels are elevated in TMZ-refractory specimens and confer poor prognosis. Our findings suggest targeting NFAT5 methylation as an effective therapeutic strategy to improve TMZ response in tumors with EGFR activation.
Die Nachhaltigkeitschallenge
Authors: Rau Henriette , Nicolai Susanne , Stoll-Kleemann Susanne
Published: May 2022

Der erstmalig in dieser Form aufgetretene kontinuierliche Wechsel zwischen Präsenz-, Online- oder Hybrid-Lehre während der COVID-19-Pandemie bringt die bisherige Tradition von Präsenzlehre und -lernen an ihre Grenzen. Um diesen neuen Ansprüchen gerecht zu werden, wurde die „Nachhaltigkeitschallenge“ für (Lehramts-)Studierende entwickelt, welche eine methodische Mischung aus Gamification-Intervention mit Commitment (Deutsch: Selbstverpflichtung), flipped classroom, Wochenplanunterricht und Wissensstrukturierung darstellt. Unterstützt wird die Challenge durch ein Online-Glossar, Impulsvorträge und Gruppenpuzzles in den Lehreinheiten sowie Aufgaben zur Wissenserarbeitung und Reflexion. Ziel ist es, eine neue Möglichkeit zu schaffen, auch bei sozialer und räumlicher Distanz die Lernerfahrung zu vertiefen sowie ein Lehr-Tool zur Verfügung zu stellen, mit dessen Hilfe ein Wechsel zwischen Online-, Präsenz- und Hybrid-Lehre ohne Umstellungen der Lehrinhalte und Vermittlungsformate möglich ist.Die Nachhaltigkeitschallenge wurde bereits im Hochschulbereich in der Präsenz-, Hybrid- und Online-Lehre erfolgreich angewendet, ist aber auch im Schulalltag umsetzbar. Insbesondere bei der Online-Lehre mit langanhaltender räumlicher und sozialer Distanz ergaben sich Vorteile bei der Nutzung dieses Lehrformats.
Online-Lehre zu Zeiten von Corona
Authors: Spieler Benadette
Published: May 2022

Die Informatik-Didaktik ermöglicht es, unter Einsatz vielseitiger Technologien neue Unterrichtsideen zu entwickeln, die dann gemeinsam mit Schüler*innen kreativ oder auch spielerisch umgesetzt werden können. Um Informatik auch im Schulunterricht zu verankern, streben viele deutsche Bundesländer die Integration eines Pflichtfaches Informatik an, so auch Niedersachsen: An der Universität Hildesheim können Lehramtsstudierende Informatik als Erst-/Zweit- oder Drittfach seit 2016/2017 wählen. Die Möglichkeit, erste Erfahrungen im Unterricht und im Umgang mit Schüler*innen zu sammeln, stellt dabei einen wichtigen Teil des Lehramtsstudiums dar und wird durch Praxissemester in Kooperation mit Schulen ermöglicht. Im ‚Corona-Jahr‘ 2020 blieb diese Praxiserfahrung vielen Studierenden aufgrund von Schulschließungen verwehrt. Dieser Beitrag beschreibt die pandemiebedingte Umstellung von Veranstaltungen der Informatik-Didaktik auf die Online-Lehre und zeigt umgesetzte Online-Konzepte und Erkenntnisse aus Erfolgen und Misserfolgen. Die Ergebnisse werden auf der Grundlage von Studierendenevaluationen und Selbstreflexionen der Studierenden präsentiert.
Über physische Distanz und emotionale Nähe im Fernunterricht
Authors: Turner Agnes , Scherde Tamina-Melanie
Published: May 2022

Die COVID-19 Pandemie hat den Schulalltag schlagartig verändert und war für die meisten Schüler*innen und Lehrer*innen durch Fernunterricht geprägt. Aufgrund der fortgeschrittenen Digitalisierung im Alltag und der Implementierung der Digitalen Grundbildung in Österreich (vgl. BMBWF 2018) sollte ein rascher Wechsel zum online-basierten Unterricht erfolgen. Dennoch waren jene Zeiten durch Herausforderungen, Unsicherheiten sowie physische Distanz für Lehrer*innen und Schüler*innen gekennzeichnet. Eine förderliche Lehr-Lernbeziehung sowie ein emotional positiver Kontakt sind neben technischem Equipment und digitalen Kompetenzen wesentliche Prädiktoren für gelingendes Lernen im digitalisierten (Fern-)Unterricht. In diesem Beitrag wird der Frage nachgegangen, inwiefern es Lehrer*innen in Zeiten des online-basierten Fernunterrichts gelungen ist, mit den Schüler*innen in (emotionalen) Kontakt zu bleiben.
Hybrid-Lehre: Klar! Aber wie?
Authors: Stoppe Valentin , Knaus Thomas
Published: May 2022

Dieser Beitrag stellt ein hybrides Lehrkonzept vor, das im Rahmen einer (synchronen) Lehrveranstaltung an der PH Ludwigsburg erprobt und evaluiert wurde. Das hier beschriebene Hybrid-Konzept ermöglicht allen Teilnehmenden vor Ort sowie den online zugeschalteten Teilnehmer*innen eine interaktive Beteiligung an der (synchronen) Lehrveranstaltung: Anders als in üblichen Hybrid-Veranstaltungen, in denen verhinderte (beispielsweise erkrankte) Teilnehmer*innen als passive Zuschauer*innen die Lehrveranstaltung lediglich mitverfolgen können, ermöglicht das vorgestellte Konzept, dass alle Teilnehmer*innen miteinander sprechen und sich gegenseitig sehen können. Diese aktive Mitwirkung und die dadurch ermöglichte gemeinschaftliche Zusammenarbeit ist gerade in universitären Seminaren und Tutorien zentral. Der vorliegende Beitrag thematisiert die Konzeption, die technische Umsetzung sowie die Evaluation des Konzepts.
What Can We Do with the Data of Deceased People? A Normative Proposal
Authors: de Miguel Beriain Iñigo , Duardo Sánchez Aliuska , Castillo Parrilla José Antonio
Published: May 2022

The health and genetic data of deceased people are a particularly important asset in the field of biomedical research. However, in practice, using them is compli- cated, as the legal framework that should regulate their use has not been fully developed yet. The General Data Protection Regulation (GDPR) is not applicable to such data and the Member States have not been able to agree on an alternative regulation. Recently, normative models have been proposed in an attempt to face this issue. The most well- known of these is posthumous medical data donation (PMDD). This proposal supports an opt-in donation system of health data for research purposes. In this article, we argue that PMDD is not a useful model for addressing the issue at hand, as it does not consider that some of these data (the genetic data) may be the personal data of the living relatives of the deceased. Furthermore, we find the reasons supporting an opt-in model less convincing than those that vouch for alternative systems. Indeed, we propose a normative framework that is based on the opt-out system for non-personal data combined with the application of the GDPR to the relatives’ personal data.
Understanding of India’s History in Social Philosophy of Rabindranath Tagore
Authors: Скороходова Т.Г.
Published: May 2022

На основе анализа философских трудов Рабиндраната Тагора в статье представлена реконструкция его понимания процессов и смыслов истории Индии. Подход к истории родной страны задан стремлением Тагора раскрыть её действительное содержание в сопоставлении с другими странами и цивилизациями. Антропологически ключевой историософской идеей Тагора является мысль о человеческой свободе, воплощающейся в истории цивилизации во множестве измерений; отсюда его понимание истории как устремленности в будущее. Тагор создал особую «философию индийской истории» как истории её социальной жизни, духа и культуры. В основе его общего понимания истории страны лежит идея «Большой Индии» – древней цивилизации с выдающейся способностью объединять все народы и разрешать конфликты. Цель и идеал заключаются в её стремлении к гармоническому «единству в многообразии» в истории, а политическая и экономическая эволюция составляет её фон. Культурная и духовная жизнь в этой философии полагаются главным наследием и перспективой развития Индии.

Based on analysis of philosophical works by Rabindranath Tagore, the article presents a reconstruction of his understanding of meanings and processes of India’s history. Tagore’s approach to native history is determined his striving for discovery of its real content in juxtaposition with other countries and civilizations. Anthropologically, the key historiosophical idea by Tagore is an idea of human freedom embodied in history of civilizations in many aspects, therefore, he understands history as an orientation for future. Tagore had created special philosophy of Indian history as history of her social life, spirit and culture. The general understanding of India’s history by R. Tagore had united idea of ‘Greater India’ – ancient civilization with outstanding ability to integrate all peoples and to resolve conflicts, as well as ideas of striving to harmonic ‘unity in diversity’ in history as its goal and ideal, of political and economic evolution as the background. Cultural and spiritual life ground main heritage and perspective of development of India.
Pavel Grigorievich Mizhuev in the Communicative Space of N. I. Kareev
Authors: Чикалова И.Р.
Published: May 2022

Автор реконструирует коммуникативные связи между двумя историками – Павлом Григорьевичем Мижуевым и Николаем Ивановичем Кареевым. Мижуев, ученый второго ряда на фоне мэтра, не являвшийся полноправным членом профессиональной корпорации дореволюционных историков, вошел в нее в качестве преподавателя трех факультетов Петроградского университета после Революции. Мижуев был последователем умеренно-либеральной и позитивистской школы Кареева, еще в дореволюционный период создавший цельную картину разных сторон жизни Великобритании и доминионов в их исторической динамике, колониальной политики Англии, издавший первую в России историю США, Канады, Австралии и Новой Зеландии. И хотя имя Мижуева не появляется в воспоминаниях Кареева, он, хоть и скромно, но присутствовал в его коммуникативном пространстве, например, приняв участие в проектах, которые курировал Кареев, – в серии книг «История Европы по эпохам и странам в Средние века и Новое время», в «Новом энциклопедическом словаре» Брокгауза и Ефрона, а также публикуясь с ним в одних изданиях и работая в течение пяти лет на одной кафедре и факультете.

The author reconstructs the communication links between two historians – Pavel Grigori-evich Mizuev and Nikolai Ivanovich Kareev. Mizhuev, a second-tier scientist against the background of the master, who was not a full-fledged member of the professional corporation of pre-revolutionary historians, entered it as a teacher in three faculties of Petrograd University after the Revolution. Mizhuev was a follower of the moderately liberal and positivist school of Kareev, who back in the pre-revolutionary period created an integral picture of different aspects of the life of Great Britain and the dominions in their historical dynamics, the colonial policy of England, and published the first history of the USA, Canada, Australia and New Zealand in Russia. And although the name of Mizuev does not appear in Kareev's memoirs, he, albeit modestly, was present in his communicative space, for example, taking part in projects supervised by Kareev, in the series of books «History of Europe by Era and Countries in the Middle Ages and New time» in the «New Encyclopedic Dictionary» of Brockhaus and Efron, as well as publishing with him in the same editions and working for five years at the same department and faculty.
The New Story of the Word / A New Word in History: Forensic
Authors: Еремеева С.А.
Published: May 2022

Forensic turn остался невидимым для российских гуманитарных исследований. Можно предположить наличие внешних и внутренних причин для этого. Первые – политические: подобные исследования не приветствуются государством. Вторые – академические: такие исследования выходят за привычные рамки гуманитарных на-ук. Они предполагают сотрудничество исследователей с активистами, журналистами, художниками. Примеров реализации такого опыта у нас нет. Тем не менее запрос на подобный подход существует, и, возможно, он будет реализован позднее.

The forensic turn went unnoticed in Russian humanitarian studies. It can be assumed that there are both external and internal reasons for this. The former is political: such studies are not approved of by the authorities now. The latter is academic: such studies go beyond the frames of habitual humanities research. It presupposes collaboration of researchers with activists, journalists and artists. We have no examples of such experience. Nevertheless, there is a request for the approach, and it is possible that it will be implemented in the future in Russia.
Mary Ann Christian, Exercising Social and Spatial Agency: An isolated island case
Authors: Albert Donald Patrick
Published: May 2022

Mary Ann Christian (1793–1866) was the only daughter of chief Bounty mutineer Fletcher Christian and his Tahitian consort Mauatua who settled on Pitcairn Island in 1790. After a violent first decade, and one death to a natural cause, the male population was reduced to a sole male survivor – John Adams. This created a female-dominated milieu within which Many Ann Christian operated with a strong degree of agency across social hierarchies involving island and empire actors, and spatially with her on- and off-island movements. While still a teenager, Mary Ann Christian became the inspiration for Mary Russell Mitford’s exquisite protagonist in Christina: The Maid of the South Seas: A Poem (1811). Almost three decades later, Lieutenant Lowry visiting from the Sparrowhawk dubbed her a cantankerous “old maid” for her concern that girls aged 13, 14, and 15 were too young for marriage; male dominance had reasserted itself. Primary and other credible sources, including demographics, document the events surrounding Herstory.
Health Risk Factors and Refugee Children in Bangladesh
Authors: Parvin Nusrat
Published: May 2022

In the Cox's Bazar refugee camps, around 855,000 Rohingya people live, with 54 percent of them being children. In Myanmar, these children were denied access to adequate healthcare, immunizations, food & nutrition, hygiene, and education. Since August 2017, when the Rohingya were forced to flee from Myanmar to Bangladesh due to the Myanmar military's brutality, they have become more vulnerable. Children were vulnerable to hunger and various infectious diseases as a result of the fighting and displacement, which posed serious health hazards. The numerous health risk factors of the children were analyzed in this study in order to provide a picture of the refugee camp.
Method: In December 2017, a questionnaire was used to assess the shelter and camp environment, food and nutrition, WASH knowledge and practice, vaccination and immunisation, medication and supplements, and education of 120 parents of Kutupalong camp no 4, OO zone.
Result: The health of 29% of the children was better than a year before, while 68 percent of the children had the same result as the previous year. Breakfast and supper were consumed by 96.67 percent of the children, and 80.8 percent were fed three times lunch and supper, with 63 percent agreeing that the camp setting was not ideal for their growth. 61 percent of families could provide enough water for their children using the water containers provided by various NGOs (Non-governmental Organisations). Despite the fact that the water sources are not close to their homes, 98.3 percent of families use tube well water. Only 49.2 percent of parents said the latrines had enough water for bathing and cleaning, while 29.2 percent said they had adequate lighting and were in their suitable placements. After using the restroom, 66.7 percent of children used soap, 16.7% used soil or ashes, and the rest used nothing. Vaccinations had been given to 91.7 percent of Rohingya children. In Bangladeshi refugee camps, 56.2 percent of Rohingya children were educated by learning centers run by various NGOs and Maktabs (Muslim kids were taught Quran in masjids).
Limitations: This report has relatively limited data that does not provide a comprehensive picture of the children's camp situation.
Conclusion: Based on the findings of the study, the camp's status may be improved if the children and their families were given good WASH knowledge and introduced to the WASH awareness programme, proper water supply and sanitation, and health care as needed.
Impact of COVID-19 on financial integration: Study on BRICS
Authors: Rajput Namita , Sufiya
Published: May 2022

The paper examines the shift in stock indices’ behavior in BRICS nations, prior to and following the outbreak of the COVID-19 pandemic, using daily data of relevant stock indices from April 2019 to March 2021. The study seeks to ascertain the influence of COVID-19 on stock markets of BRICS countries. The descriptive analysis and graphical presentation established that the pandemic period was extremely variable, with high average returns. Furthermore, the findings reveal that, with the exception of China and South Africa, the BRICS nations’ stock indices were not cointegrated prior to the epidemic. Interdependence has increased throughout the epidemic, as three BRICS nation pairings, particularly Brazil and China, China and South Africa, and Russia and South Africa, are all cointegrated. This demonstrates that the COVID-19 problem strengthened the BRICS countries’ cointegration or relatedness. As a result, portfolio diversification opportunities have dwindled. Additionally, given the relatively high average stock indices, investors may generate significant returns by investing in indices rather than individual firms, especially during the pandemic crisis time.
Imaging methods in the differential diagnosis of retinoblastoma, Coats’ disease and primary persistent hyperplastic vitreous
Authors: Artemenko Yu. V. , Panferova T. R. , Mikhailova E. V. , Kyun Yu. , Ushakova T. L. , Polyakov V. G.
Published: May 2022

The detection of an intraocular embryonic tumor – retinoblastoma (RB) – in children and its differential diagnosis with diseases mimicking RB is an important task of imaging. Considering that the clinical and radiological patterns of RB and the diseases mimicking it may be similar, and the choice of a treatment strategy is carried out without preliminary histological examination, the primary diagnosis is of decisive importance. A comprehensive diagnostic approach for suspected RB provides a timely choice of optimal treatment tactics and improves prognosis. The article presents the most demonstrative own observations. The literature review includes the modern possibilities of non-ionizing radiation diagnostics of RB and diseases mimicking as it.
The use of proton radiation therapy in a patient with melanotic neuroectodermal tumor of infants of the anterior fontanel: description of a clinical case
Authors: Faseeva N. D. , Martynova N. I. , Maksimov M. D. , Boyko K. F. , Vorobyev N. A. , Berezina N. A. , Plakhotina N. A. , Reshchikov D. A. , Vasiliev I. G. , Mai R. B. , Titova M. A. , Zheludkova O. G.
Published: May 2022

Melanotic neuroectodermal tumor (MNET) of infants is a rare benign neoplasm detected mainly in children of the first year of life. Standard therapy consists of radical surgical removal of the tumor. Currently, the treatment of patients with recurrent and unresectable forms of the disease is relevant. The number of publications using polychemotherapy and radiation therapy is extremely limited. This article describes a clinical case of the occurrence of MNET in the anterior fontanel with a recurrent course. Proton radiation therapy was chosen as an alternative treatment method.
Люминесцентные и дозиметрические свойства керамик оксида магния, синтезированных в потоке высокоэнергетических электронов
Authors: Никифоров С.В. , Лисицын В.М. , Ананченко Д.В. , Касаткина Я.П. , Голковский М.Г. , Ищенко А.В.
Published: May 2022

Впервые получены образцы керамики оксида магния методом, основанным на облучении шихты потоком быстрых электронов. Исследованы и идентифицированы центры свечения в полученных образцах, связанные с собственными и примесными дефектами. Проведен сравнительный анализ кривых термолюминесценции (ТЛ) и дозовых зависимостей ТЛ керамик MgO, полученных радиационным и термохимическим методами. Показано, что основным достоинством синтезированных радиационным методом керамик, важным для их использования в высокодозной ТЛ-дозиметрии, является линейная дозовая зависимость пика ТЛ при 370 K при облучении импульсным электронным пучком (130 keV, 1.5-30 kGy). Обсуждаются возможные причины улучшения линейности дозовой характеристики вновь созданных керамик по сравнению с аналогами. Ключевые слова: оксид магния, термолюминесцентная дозиметрия, дозовая характеристика, кислородные вакансии, импульсная катодолюминесценция.
Электрокинетический ретранслятор акустических колебаний
Authors: Шарфарец Б.П. , Дмитриев С.П. , Курочкин В.Е. , Легуша Ф.Ф.
Published: May 2022

Показано, что в электрокинетическом акустоэлектрическом преобразователе при приложении постоянного электрического поля (напряжения накачки) в процессе приема акустического сигнала возникает возможность ретрансляции исходного внешнего акустического поля. Это происходит вследствие наличия в преобразователе одновременно обратных электрокинетических явлений: электроосмоса и потенциала течения. Приведены необходимые теоретические обоснования этого явления. Представлены данные натурного эксперимента, подтверждающие теорию. Ключевые слова: акустоэлектрическое преобразование, электрокинетические явления, потенциал течения, накачка энергии, электрокинетический ретранслятор.
Development of a Mobile Assessment Tool for Understanding Social Comparison Processes Among Individuals With Schizophrenia: Two-Phase Survey Study (Preprint)
Authors: Arigo Danielle , Torous John
Published: May 2022

BACKGROUND

Digital tools may help to address social deficits in schizophrenia, particularly those that engage social comparison processes (ie, evaluating oneself relative to others). Yet, little is known about social comparison processes in schizophrenia or how best to capture between- versus within-person variability, which is critical to engaging comparisons in digital interventions.

OBJECTIVE

The goals of this pilot study were to (1) better understand affective responses to social comparisons among individuals with schizophrenia, relative to healthy controls, using a validated global self-report measure; and (2) test a new brief, mobile assessment of affective responses to social comparison among individuals with schizophrenia, relative to the full measure. This study was conducted in 2 phases.

METHODS

We first compared self-reported affective responses to social comparisons between individuals with schizophrenia (n=39) and healthy controls (n=38) using a traditional self-report measure, at 2 time points. We examined the temporal stability in responses and differences between groups. We then evaluated the performance of brief, mobile assessment of comparison responses among individuals with schizophrenia, completed over 12 weeks (n=31).

RESULTS

Individuals with schizophrenia showed greater variability in affective responses to social comparison than controls on traditional measures and completed an average of 7.46 mobile assessments over 12 weeks. Mobile assessments captured within-person variability in affective responses in the natural environment (intraclass correlation coefficients of 0.40-0.60). Average scores for mobile assessments were positively correlated with responses to traditional measures.

CONCLUSIONS

Affective responses to social comparison vary both between and within individuals with schizophrenia and capturing this variability via smartphone surveys shows some evidence of feasibility. As affective variability is a potential indicator of poor outcomes among individuals with mental health conditions, in the future, a brief, mobile assessment of affective responses to social comparisons may be useful for screening among individuals with schizophrenia. Further research on this process is needed to identify when specific comparison messaging may be most effective in digital interventions and could suggest new therapeutic targets for illnesses such as schizophrenia.
Impact of COVID-19 on Maternal health services: A review (Preprint)
Authors: pareek shatrughan
Published: May 2022

UNSTRUCTURED

Corona virus disease (COVID-19) outbreaks caused significant mortality and morbidity at global level. Maternal and child health services are one the most affected services during the pandemic. Respectful maternity care (RMC) is an essential component of high-quality maternal care, according to the WHO framework for quality care for pregnant women and newborns. The aim of this study was to provide a review of COVID-19 impact on Maternal and child health services. The Web of Science, Scopus, and PubMed databases were systematically searched. Articles reporting Maternal and child health services, coronavirus disease (COVID-19), coronavirus and RMC were included for assessment. The initial search resulted in 106 records. After the primary screening of titles, abstracts, and full texts and removing duplicates, 11 articles were selected and included in this review study. The findings revealed that range of projected maternal mortality and child mortality were 1.3% -38.6% and 9.8%–44.7% . Additionally, the review highlighted that there is a huge impact of COVID-19 on utilization of reproductive, maternal, and newborn health services. Moreover, the study also reported huge increases in maternal mental health issues, such as clinically relevant anxiety and depression. There is need to identify the factors and prompt management of maternal health services during COVID-19. Hence, clinicians should maintain RMC and MCH during any pandemic.
MICA: Motivational Interviewing Conversational Agent for Parents as Proxies for their Children in Healthy Eating (Preprint)
Authors: Smriti Diva , Kao Tsui-Sui Annie , Rathod Rahil , Shin Ji Youn , Peng Wei , Williams Jake , Mujib Munif Ishad , Colosimo Meghan , Huh-Yoo Jina
Published: May 2022

BACKGROUND

Increased adoption of off-the-shelf conversational agents (CAs) brings opportunities to integrate therapeutic interventions. Motivational Interviewing (MI) can then be integrated with CAs for cost-effective access to MI. MI can be especially beneficial for parents who often have low motivation due to limited time and resources to eat healthy together with their children.

OBJECTIVE

We developed MICA—Motivational Interviewing Conversational Agent to improve healthy eating in parents who serve as a proxy for health behavior change in their children. Proxy relationships involve a person serving as a catalyst for behavior change in another person. Parents, serving as proxies, can bring about a behavior change in their children.

METHODS

We conducted user test sessions of MICA to understand the perceived acceptability and usefulness of MICA by parents. Twenty-four parents of young children participated in two user test sessions with MICA, approximately two weeks apart. After parents’ interaction with MICA in each user test session, we used qualitative interviews to understand parents’ perceptions and suggestions for improvements in MICA.

RESULTS

Findings showed participants’ perceived usefulness of MICA for helping them self-reflect and motivating them to adopt healthier eating habits together with their children. Participants further suggested various ways MICA can help them safely manage their children’s eating behaviors and provide customized support for their proxy needs and goals.

CONCLUSIONS

We discuss how the user experience of CAs can be improved to uniquely offer support to parents who serve as proxies in changing the behavior of their children. We end with implications for a larger context of designing MI-based CAs for supporting proxy relationships for health behavior change.
The perceived ease of use and perceived usefulness of a web-based interprofessional communication and collaboration platform in the hospital setting: lessons for future system designers. (Preprint)
Authors: Nie Jason X , Heidebrecht Christine , Zettler Andrea , Pearce Jacklyn , Cunha Rafael , Quan Sherman , Mansfield Elizabeth , Tang Terence
Published: May 2022

BACKGROUND

Hospitalized patients with complex care needs require an interprofessional team of health professionals working together to support their care in hospital and during discharge planning. However, interprofessional communication and collaboration in the inpatient setting is often fragmented and inefficient, leading to poor patient outcomes and provider frustration. Health information technology can potentially help improve team communication and collaboration, but to date, evidence of their effectiveness is lacking. There are also concerns that current implementations further fragment and increase clinician burden without proven benefits.

OBJECTIVE

To generate transferrable lessons for future designers of health information technology tools to facilitate team communication and collaboration.

METHODS

A secondary analysis of the qualitative component of a mixed methods evaluation was carried out. The electronic communication and collaboration platform was implemented on two general internal medicine wards in a large community teaching hospital in Mississauga, Ontario, Canada. Fifteen inpatient clinicians on those wards, including nurses, physicians, and allied healthcare providers, were recruited to participate in semi-structured interviews about their experience with a co-designed electronic communication and collaboration tool. Data was analyzed using the Technology Acceptance Model (TAM), and themes relating to the constructs of Perceived Ease Of Use (PEOU) and Perceived Usefulness (PU) were identified.

RESULTS

: A secondary analysis guided by the TAM highlighted the following. Intuitive design removed training as a barrier for use, but lack of training may hinder participants’ PEOU if features designed for efficiency are not discovered by users. Organized information was found to be useful for creating a comprehensive clinical picture of each patient and facilitating improved handovers. However, information needs to be both comprehensive and succinct at the same time, or else information overload may negatively impact PEOU. The mixed paper and electronic practice environment also negatively impacted PEOU due to unavoidable double documentation and need for printing. Participants perceived the tool to be useful as it improved efficiency in information retrieval and documentation, improved the handovers process, afforded another mode of communication when face-to-face communication was impractical, and improved share awareness. The PU of this tool is dependent on its utilization, and is optimized when all team members use it.

CONCLUSIONS

Electronic tools can support communication and collaboration for interprofessional teams caring for complex patients. There are transferable lessons learned that can improve PU and PEOU of future systems.