bluuebunny/crossref_metadata_2025 huggingface dataset:
Changing Pain Management Strategy from Opioid-centric Towards Improve Postoperative
Cognitive Dysfunction with Dexmedetomidine
Authors: Su Chunhong , Ren Xiaojun , Wang Hongpei , Ding Xiaomei , Guo Jian
Published: November 2021

Objective:

This study was aimed to investigate the effectiveness of dexmedetomidine (DEX) on improving
the level of pain and disability to find out the possible correlation between psychological factors with pain management
satisfaction and physical function in patients with femoral neck fractures.

Methods:

One hundred twenty-four adult patients with stable femoral neck fractures (type I and II, Garden classification)
who underwent internal fixation, were prospectively enrolled including 62 patients in the DEX group and 62
patients in the control group. The magnitude of disability using Harris Hip Score, Postoperative Cognitive Dysfunction
(POCD) using Mini-Mental State Examination (MMSE score), Quality of Recovery (QoR-40), pain-related
anxiety (PASS-20), pain management and pain catastrophizing scale (PCS) were recorded on the first and second day
after surgery.

Results:

The DEX group on the first and second days after surgery exhibited higher quality of recovery scores,
greater satisfaction with pain management, low disability scores, less catastrophic thinking, lower pain anxiety,
greater mini mental state examination scores and less opioid intake and the differences were statistically significant
compared with the control group (P<0.001). Emergence agitation and incidence of POCD were significantly less in
the DEX group (P<0.001). Decreased disability was associated with less catastrophic thinking and lower pain anxiety,
but not associated with more opioid intake (P<0.001). Higher QoR-40 scores had a negative correlation with
more catastrophic thinking and more opioid intake (P<0.001). Greater satisfaction with pain management was correlated
with less catastrophic thinking and less opioid intake (P<0.001).

Conclusion:

Using DEX as an adjunct to anesthesia could significantly improve postoperative cognitive dysfunction
and the quality of recovery and these improvements were accompanied by decrease in pain, emergence agitation, and
opioid consumption by DEX administration. Since pain relief and decreased disability were not associated with prescribing
greater amounts of opioid intake in the patients, improving psychological factors, including reducing catastrophic
thinking or self-efficacy about pain, could be a more effective strategy to reduce pain and disability, meanwhile
reducing opioid prescription in the patients. Our findings showed that DEX administration is safe sedation with
anti-inflammatory, analgesic and antiemetic effects and it could help change pain management strategy from opioidcentric
towards improved postoperative cognitive dysfunction.
Angelica archangelica and Ginkgo biloba Extracts Recover Functional Blood
Hemoglobin Derivatives in Rabbits Exposed to High Altitude
Authors: Gamal-Eldeen Amira M. , Raafat Bassem M. , Almehmadi Mazen M. , El-Daly Sherien M. , Faizo Nahla L. , Althobaiti Fayez
Published: November 2021

Background:

Shortage of oxygen is a common condition for residents of high-altitude (HA) areas. In mammals, hemoglobin (Hb) has four derivatives: oxyhemoglobin (Hb-O2), carboxyhemoglo-bin (Hb-CO), sulfhemoglobin (Hb-S), and methemoglobin (Met-Hb). In HA areas, aberrant physio-logical performance of blood hemoglobin is well-established.

Objective:

The study aimed to investigate the influence of 30 days of HA residence on rabbits' total Hb, Hb derivatives, Hb autooxidation rate, and antioxidant enzymes in comparison to low-altitude control rabbits. Further, the study aimed to investigate the effect of antioxidant-rich Angelica archan-gelica and/or Ginkgo biloba extracts on the same parameters in HA-resident rabbits.

Methods:

Rabbits subjected to 30 days of HA residence were compared to low-altitude control rabbits. HA-residence rabbits were then orally administered 0.11 g/kg b.wt. of Angelica archangelica and/or Ginkgo biloba extract for 14 days. Hb derivatives and Hb autooxidation rate were measured spectro-photometrically. Antioxidant enzymes were estimated using specialized kits.

Results:

Compared to low-altitude rabbits, 30-day HA-residence rabbits showed a noticeable increase (p<0.05) in Hb-O2 and Hb-CO concentration. In addition, Met-Hb concentration, autooxidation rate of Hb molecules, and activities of superoxide dismutase (SOD) and glutathione peroxidase (GPx) exhib-ited a remarkable increase in HA-residence rabbits (p<0.01), reflective of rapid ROS generation. In HA-residence rabbits, both individual and combined treatment with antioxidant-rich extracts for 14 days resulted in recovery to near-normal functional levels of Hb-O2 and Met-Hb, Hb autooxidation rate, and activities of SOD and GPx, while only combined treatment led to Hb-O2 recovery.

Conclusion:

The findings suggest that functional Hb levels may be recovered by oral administration of A. archangelica, G. biloba, or combined treatments. In conclusion, oxidative stress due to living in HA areas may be avoided by supplementation with natural antioxidants.
CCNE1 Promotes Progression and is Associated with Poor Prognosis in
Lung Adenocarcinoma
Authors: Zhang Lili , Ma Guoliang , Yang Lulu , Dong Jing
Published: November 2021

Background:

Mounting evidence has shown that Cyclin E1 (CCNE1) facilitates various carcinoma progression, but its function in lung adenocarcinoma (LUAD) remains unclear.

Objective:

Our study aims to explore the significance of CCNE1 in clinical progression and study its biological functions in LUAD.

Methods:

CCNE1 expressions in LUAD specimens and cells were detected through quantitative real-time polymerase chain reaction (qRT-RCR) and western blot. An immunohistochemistry technique was used to detect CCNE1 expression to explore its association with clinical parameters. The LUAD cells with stable knockdown of CCNE1 were constructed by small interfering RNA. The effect of CCNE1 on LUAD cells proliferation and apoptosis was evaluated through Cell Counting Kit-8 (CCK-8), colony formation, and Annexin V/propidium iodide (AV-PI) assays, respectively. The cell migration and invasion were evaluated by Wound-healing and Transwell assays, respectively. The xenograft and lung metastasis mouse models were introduced to analyze how CCNE1 knockdown affects tumor growth and tumor metastasis.

Results:

CCNE1 expression was upregulated in LUAD tissue and cells. CCNE1 knockdown inhibited LUAD cellular malignant behavior in vitro and reduced tumor growth and metastasis in vivo. High expression of CCNE1 was correlated with big tumor size, cancer stage, lymph node metastasis, and poor prognosis.

Conclusions:

CCNE1 overexpression promotes LUAD growth, metastasis, and forebode poor prognosis: it can serve as a new prognostic marker of LUAD.
The Prognostic Significance of White Blood Cell and Platelet Count for Inhospital Mortality and Pneumonia in Acute Ischemic Stroke
Authors: You Shoujiang , Sun Xin , Zhou Yi , Zhong Chongke , Chen Juping , Zhai Wanqing , Cao Yongjun
Published: November 2021

Background:

We investigated the combined effect of white blood cell (WBC) and
platelet count on in-hospital mortality and pneumonia in acute ischemic stroke (AIS) patients.

Methods:

A total of 3,265 AIS patients enrolled from December 2013 to May 2014 across 22 hospitals
in Suzhou city were included in the present study. We divided patients into four groups according
to their level of WBC and platelet count: LWHP (low WBC and high platelet), LWLP (low
WBC and low platelet), HWHP (high WBC and high platelet), and HWLP (high WBC and low
platelet). A logistic regression model was used to estimate the combined effect of WBC and
platelet counts on all-cause in-hospital mortality and pneumonia in AIS patients.

Results:

HWLP was associated with a 2.07-fold increase in the risk of in-hospital mortality in comparison
to LWHP (adjusted odds ratio (OR) 2.07; 95% confidence interval (CI), 1.02-4.18; P-trend
=0.020). The risk of pneumonia was significantly higher in patients with HWLP than those with
LWHP (adjusted OR 2.29; 95% CI, 1.57-3.35; P-trend <0.001). The C-statistic for the combined
WBC and platelet count was higher than WBC count or platelet count alone for the prediction of in-
-hospital mortality and pneumonia (all P < 0.01).

Conclusion:

High WBC count combined with a low platelet count level at admission was independently
associated with in-hospital mortality and pneumonia in AIS patients. Moreover, the combination
of WBC count and platelet count level appeared to be a better predictor than WBC count or
platelet count alone.
Patient Centered Studies Focused on Type 2 Diabetes Management, Education,
and Family Support: A Scoping Review
Authors: Rosenthal Meagen , Arnold Austin , Salkar Monika , Patelb Sahil , Harrell Emily , Aldridge Harleigh , Mancuso Blake
Published: November 2021

Background:

Although a large amount of research has been conducted in diabetes management,
many of the articles do not focus on patient-centered questions and concerns. To address
this shortcoming, patients and various other stakeholders from three northern Mississippi communities
co-created research questions focused on Type 2 diabetes management.

Objective:

To identify the diabetes management literature pertaining to each of the six patient-developed
research questions from March 2010 to July 2020.

Methods:

A scoping review was conducted via PubMed to identify research articles from March
2010 to July 2020 focused on patient-centered Type 2 diabetes studies relevant to the six research
questions.

Results:

A total of 1,414 studies were identified via the search strategy and 34 were included for
qualitative analysis following article exclusion. For one of the research questions, there were no articles
included. For the remaining research questions, the number of articles identified ranged from
two to eleven. After analysis of the included articles, it was found that these questions either lacked
extensive data or had not been implemented in the practice of diabetes management.

Conclusion:

v
Effects of Smokeless Tobacco Samples from Tabuk Saudi Arabia on Nitric
Oxide Production: A Potential Risk for Cancer and Cardiovascular Diseases
Authors: Jabeen Almas , Mesaik Muhammed Ahmed , Saeed Maria , Zaheer Ul-Haq  , Ahmed Izzaddinn Elawad , Ibrahim Mohammed Yassin , Mirghani Hyder Osman , Khalid Asaad
Published: November 2021

Background:

Smokeless tobacco (SLT) is traditionally used in Middle East countries.
The several toxic constituents with potential carcinogenicity make it a serious human health risk.
Literature regarding their effects on cardiac and cancer disease is lacking in Saudi Arabia.

Objective:

This study was conducted to investigate the adverse effect of 11 different samples of
widely used SLT varieties from the Tabuk region - Saudi Arabia, on Nitric Oxide (NO) level and
their potential risk on cardiovascular health, etiology and/or progression of cancers.

Methods:

Samples were collected from Tabuk, KSA and analyzed by the GC-MS technique. Nitric
oxide inhibition was performed using J774.2 macrophages by the Griess method. The retrieved
crystallized structure of human inducible nitric oxide synthase (iNOS) from Brookhaven Protein
Data Bank Repository PDB I.D: 3E7G with 2.20Å resolution was further prepared by structure using
the MOE.2019 tool. The compounds abstracted from 11 different Shammah varieties were
sketched by the MOE-Builder tool. Minimization for both receptor and compounds was performed
via AMBER99 and MMFF99X force field implemented in MOE.

Results:

Nine samples (4 - 11) showed a potent suppressive effect on NO production with IC50 values
ranging between (16.9-20.4 μg/mL), respectively. The samples (1 & 2) exhibited a moderate
level of inhibition with IC50 ranging between 33.2 and 57.4 μg/mL, respectively. Interestingly,
sample 4 consisting of compounds (13-15, 19-26, 28) that mostly belongs to the group fatty acid ester
and phthalic acid ester showed the most potent suppressive effect. Molecular docking results revealed
that the current local SLT constituents presented noticeable potency in different extract samples.

Conclusion:

Variable suppressive effects on NO were detected in the current SLT samples, where
sample 4 was the most potent among all. The extract of the latter exhibited molecular interaction
with the first shell amino acid residues of Inducible nitric oxide synthase (iNOS), which may anchor
the plasticity and selectivity of the compounds present in it. The samples (4 -11) showed a potent
inhibitory effect on the NO, where compound 26 (Phthalic acid ester) is common, and its adequate
concentration may account for augmented biological activity. These results may effectively
highlight their adverse effects on cardiovascular health and etiology and/or progression of cancer
and may help in strengthening the social and governmental efforts in minimizing the use of these
substances.
Synthesis of Antibacterial Oxide of Copper for Potential Application as
Antifouling Agent
Authors: Bhagat Neeru , Pandey Brajesh
Published: November 2021

Background:

Copper oxide nanoparticles have become very important due to their numerous
applications and ease of synthesis. Out of the two oxides of copper, cuprous oxide exhibits
better antibacterial, antimicrobial, and antifouling properties.

Objective:

The study aimed to find a way of synthesizing stable and eco-friendly oxide of copper and
test it for antibacterial properties.

Methods:

The precipitation method was employed for the synthesis of nanoparticles. NaOH and
Moringa oleifera leaves extract were used as the reducing agents to obtain two different sets of samples.

Results:

Good phases of copper oxides were formed for all the samples (cuprous as well as cupric
oxides). SEM studies showed that the structure of cupric oxide (CuO), formed at higher calcination
temperatures, is well defined when synthesized using a hybrid method.

Conclusion:

Our studies indicate that the hybrid method of synthesis used by us is a more effective
and quicker way of synthesizing cuprous oxide (Cu2O), which exhibits higher antibacterial properties
as compared to cupric oxide (CuO).
Patient, Disease, and Drug-Related Risk Factors Associated with Phenytoin-
Induced Cutaneous Adverse Drug Reactions in South Indian Epileptic
Patients - A Prospective Case-Control Study
Authors: Pattharachayakul Sutthiporn , John Shobana , Canyuk Bhutorn , Anand T.C. Vijay , Sukasem Chonlaphat
Published: November 2021

Background:

Phenytoin is the most commonly reported aromatic Anti-Epileptic Drug
(AED) to cause Cutaneous Adverse Drug Reactions (CADRs). Cutaneous adverse drug reactions
may be immune or non-immune mediated. It has been observed that predisposition is multifactorial
and that gene mutations alone cannot be the cause.

Objectives:

In this study, we investigated the patient, disease, and drug-related risk factors associated
with phenytoin-induced cutaneous adverse drug reactions in South Indian epileptic patients.

Methods:

This study was conducted as a single-center prospective case-control study over a period
of 13 months. The Fisher’s exact test and multivariate binary logistic regression analysis were used
to test the association of single and multiple variables, respectively.

Results:

This study comprised 26 patients with phenytoin-induced cutaneous adverse drug reactions
(PHT-CARDs) and 32 phenytoin-tolerant controls with a mean age of 40.60±18.15 and
36.21±14.71 years, respectively. Among 26 phenytoin-induced cutaneous adverse drug reactions,
76.92% cases were mild-moderate reactions and 23.07% were severe. The onset latency period of
these reactions ranged from 7-42 days. The multivariate analysis showed that multiple AEDs (OR
=18.62, 95% CI 4.28-80.87, p=< .001) and comorbidities (OR= 5.98, 95% CI 1.33-26.78, p=.01)
are risk factors for PHT-CADRs. PHT-SCARs were shown to be associated with previous allergy
history (OR= 31, % CI 2.40-398.8, p=.008).

Conclusion:

The risk factors found to be associated with CARDs in South Indian Epileptic patients
are multiple AEDs, comorbidities, and past allergic history. Therefore, physicians and other
associated health care professionals should closely monitor the patients when phenytoin is employed.
Finite Element Simulation and Deformation Control of High-Speed
Milling of Al7050-T7451 Thin-Walled Parts
Authors: Yang Song , Yang Jun-X. , Wang Fei-Y.
Published: November 2021

Background:

To reduce environmental pollution and improve resource utilization,
lightweight equipment has become an important development trend of manufacturing. Therefore,
thin-walled parts are being widely used in automobiles, aerospace, etc. due to their lightweight and
high specific strength. However, they usually deform during machining due to poor stiffness.

Objective:

To reduce the machining deformation, the finite element method has been used to analyze
the deformation law of thin-walled parts.

Method:

A 3D milling model of Al7050-T7451 thin-walled parts was established. Then, the influence
of hole structure, rib, and auxiliary support on the deformation was investigated under the
condition of optimized parameters. Moreover, some related patents on the research of machining
deformation of thin-walled parts were also consulted.

Results:

The results showed that the established 3D model could accurately predict the machining
deformation of thin-walled parts. The machining deformation on the edges is more severe due to
holes that weaken the stiffness of thin-walled parts. Besides, ribbed slab and auxiliary support can
shorten machining deformation by 71.9% and 65.2%, respectively.
Work Engagement sebagai Prediktor Turnover Intention pada Karyawan Generasi Millennial di PT Tri-Wall Indonesia
Authors: Wicaksono Rahmad Setyo
Published: November 2021

Penelitian ini dilakukan berdasarkan adanya fenomena tingginya turnover intention pada perusahaan yang salah satunya dimungkinkan disebabkan rendahnya work engagement, oleh sebab itu penelitian ini bertujuan untukmengetahui pengaruh work engagement terhadap turnover intention pada karyawan. Pendekatan penelitian ini menggunakan pendekatan kuantitatif dengan jenis korelasional. Populasi penelitian ini adalah karyawan operatorproduksi PT. Tri-Wall Indonesia yang berjumlah 100 karyawan dengan sampel penelitian sebanyak 50 karyawan generasi millennial yang ditentukan dengan teknik purposif. Metode pengumpulan data menggunakan skala. Analisis data dilakukan dengan analisis deskriptif dan analisis regresi linear sederhana. Hasil penelitian ini menunjukan bahwa terdapat pengaruh negatif work engagement terhadap turnover intention dengan r = -0,475 p = 0,000. Variabel work engagement berkontribusi sebanyak 70,5% terhadap turnover intention. Dalam penelitian ini partisipan memiliki tingkat work engagement sedang dengan jumlah 39 karyawan (78%), sedangkan turnover intentionmemiliki tingkat sedang dengan jumlah 34 karyawan (68%).
Hubungan Antara Kontrol Diri dengan Perilaku Konsumtif Melalui Online Shop pada Mahasiswi
Authors: Sudarisman Hergita Syi Vadila
Published: November 2021

Kemudahan dalam melakukan belanja secara online memberikan cara baru pada konsumen dalam membelibarang, sehingga hal ini dapat lebih mempermudah konsumen dalam melakukan transaksi dan cenderung berperilaku konsumtif. Sementara itu, kontrol diri merupakan hal penting untuk mengendalikan perilaku konsumtif. Penelitian ini bertujuan untuk mengetahui hubungan antara kontrol diri dengan perilaku konsumtif melalui online shop pada mahasiswi. Penelitian ini menggunakan pendekatan kuantitatif. Subjek dalam penelitian ini adalah mahasiswi Universitas Negeri Yogyakarta angkatan 2016 sebanyak 130 mahasiswi. Metode pengambilan sampel yang digunakan adalah simple random sampling. Instrumen penelitian ini menggunakan dua skala yaitu skala perilaku konsumtif melalui online shop yang terdiri dari 26 item dengan reliabilitas sebesar 0,966 serta skala kontrol diri yang terdiri dari 15 item dengan reliabilitas sebesar 0,920. Hasil analisis data menggunakan Pearson Product Moment menunjukkan bahwa terdapat hubungan antara kontrol diri dengan perilaku konsumtif melalui online shop pada mahasiswi Universitas Negeri Yogyakarta angkatan 2016, dengan nilai korelasi sebesar -0,861 dan signifikansi p < 0.05 yang artinya semakin rendah kontrol diri maka semakin tinggi perilaku konsumtif melalui online shop, begitu pula sebaliknya..
Dinamika Psikologis pada Lansia Dilihat dari Sisi Romantic Relationship Setelah Melakukan Perkawinan di Usia Lanjut
Authors: Oktariza Cynthia Ayu , Nurhayati Siti Rohmah
Published: November 2021

Penelitian ini bertujuan untuk mengetahui dinamika psikologis pada lansia setelah melakukan perkawinan di usia lanjut melalui komponen hubungan romantis yang muncul. Penelitian ini mengggunakan metode kualititaif dengan pendekatan fenomenologis. Subjek penelitian adalah lansia dengan kriteria berusia 60 tahun ke atas dan pernah melakukan perkawinan di usia lanjut. Penelitian ini menunjukkan komponen hubungan romantis yang muncul berupa, keintiman, hasrat, komitmen, harapan, penerimaan diri positif, dan munculnya masalah. Dua dari tiga pasangan yang menjadi responden menyatakan melalui proses kencan sebelum melakukan perkawinan. Perkawinan di usia lanjut identik dengan membutuhkan teman atau pendamping hidup di hari tua dengan saling berbagi perhatian, merawat, dan memenuhi kebutuhan atau keperluan pasangan serta menjalin persahabatan. Dua dari tiga pasangan masih membutuhkan proses penyesuaian untuk membangun kepercayaan dan menciptakan komunikasi yang intim. Hubungan seksual tidak menjadi kebutuhan pokok dan hal penting dalam perkawinan di usia lanjut. Lebih berbagi mengenai kebahagiaan dan kurang adanya keterbukaan mengen
Anteseden Cyberloafing pada Karyawan Perusahaan Start-up
Authors: Azzahra Muthi'ah , Romadhani Rahmatika Kurnia
Published: November 2021

Bentuk withdrawal yang banyak terjadi di tempat kerja yaitu cyberloafing. Cyberloafing adalah penggunaan akses internet, email, dan pesan instan untuk kesenangan pribadi karyawan di luar pekerjaan. Penelitian ini bertujuan mengetahui cyberloafing pada karyawan perusahaan start-up dan mengetahui anteseden cyberloafing. Penelitian ini merupakan penelitian korelasional yang dilakukan pada 66 karyawan dari berbagai perusahaan start-up. Pengambilan sampel dalam penelitian ini menggunakan teknik accidental sampling. Pengumpulan data menggunakan skala cyberloafing dan skala anteseden cyberloafing dengan skala likert yang telah diuji validitas dan reliabilitasnya. Data hasil penelitian dianalisis dengan menggunakan analisis regresi linear berganda, diperoleh nilai β sebesar 0,484 pada variabel sifat kepribadian, tuntutan dan dukungan kerja (β 0,603), gangguan pekerjaan dan keluarga (β 0,188), serta kebijakan perusahaan (β 0,488). Hasil penelitian ini menunjukkan penemuan yang baru dalam penelitian cyberloafing. Hasil analisis regresi berganda tersebut menunjukkan bahwa anteseden cyberloafing yang memiliki pengaruh terhadap cyberloafing adalah tuntutan dan dukungan pekerjaan. Sedangkan, anteseden lain yaitu sifat kepribadian, gangguan pekerjaan dan rumah, serta kebijakan perusahaan tidak memiliki pengaruh terhadap cyberloafing.
Pengaruh Beban Kerja terhadap Stres Kerja pada Guru Tahfidz di Pesantren Terpadu Darul Qur’an Mulia
Authors: Nafs Tazkiatun
Published: November 2021

Penelitian ini bertujuan mengetahui pengaruh beban kerja terhadap stres kerja pada Guru Tahfidz di Pesantren Terpadu Darul Qur’an Mulia. Beban kerja bersifat multidimensi yang terbagi menjadi 3 dimensi, yaitu: beban waktu, beban upaya mental, dan beban tekanan psikologis. Penelitian ini akan meneliti pengaruh setiap dimensi secara bersama-sama terhadap stres kerja pada Guru Tahfidz di Pesantren Terpadu Darul Qur’an Mulia. Penelitian ini adalah sebuah penelitian dengan menggunakan pendekatan kuantitatif dan termasuk penelitian ex-post facto. Subjek yang terlibat dalam penelitian ini adalah Guru Tahfidz di Pesantren Terpadu Darul Qur’an Mulia yang berjumlah 54 orang dengan cara simple random sampling. Instrumen penelitian yang dipakai adalah skala beban kerja dan skala stres kerja. Uji validitas menggunakan validitas isi yang dilakukan oleh profesional judgement. Hasil analisis butir yang dilakukan menunjukkan angka korelasi item total berkisar antara 0,278-0,579. Hasil uji reliabilitas stres kerja sebesar 0,84, dimensi beban waktu sebesar 0,767, dimensi beban upaya mental sebesar 0,743, dan dimensi beban tekanan psikologis 0,549. Berdasarkan hasil regresi linear berganda, ditemukan bahwa: (1) beban kerja, beban upaya mental, dan beban tekanan psikologis secara simultan (bersama-sama) berpengaruh terhadap stres kerja sebesar 0,375 atau 37,5 %. Sedangkan sisanya, yaitu 62,5% dijelaskan oleh variabel lain diluar model penelitian ini; (2) beban waktu tidak memiliki pengaruh positif terhadap stres kerja, dibuktikan berdasarkan nilai signifikansi 0,109;(3) beban upaya mental berpengaruh positif terhadap stres kerja, dibuktikan berdasarkan nilai signifikansi 0,005, dengan nilai sumbangan efektif 20,8%; (4) beban tekanan psikologis tidak memiliki pengaruh positif terhadap stres kerja, dibuktikan dengan nilai signifikansi 0,192.
Hubungan Perilaku Prososial dengan Persepsi Penerimaan Teman Sebaya pada Remaja Awal
Authors: Saputri Ika Apriani Dewi , Ayriza Yulia
Published: November 2021

Penelitian ini bertujuan untuk meneliti hubungan antara perilaku prososial dengan persepsi penerimaan teman sebaya pada remaja awal di SMP N 1 Ngawen, Gunungkidul. Dalam penelitian ini pendekatan yang digunakan adalah pendekatan kuantitatif dengan jenis penelitian korelasional. Populasi dalam penelitian ini berjumlah 665 siswa, dengan sampel berjumlah 96 siswa. Instrumen pengumpulan data berupa skala perilaku prososial dan skala persepsi penerimaan teman sebaya. Skala perilaku prososial terdiri dari 24 item dengan reliabilitas sebesar 0, 933 dan skala persepsi penerimaan teman sebaya terdiri dari 20 item dengan reliabilitas sebesar 0, 927. Berdasarkan hasil analisis data menggunakan korelasi product moment menunjukkan bahwa terdapat hubungan antara perilaku prososial dengan persepsi penerimaan teman sebaya pada remaja awal di SMP N 1 Ngawen dengan nilai korelasi sebesar 0, 889 dan signifikasi p0,05. Dengan demikian semakin tinggi perilaku prososial maka semakin tinggi persepsi penerimaan teman sebaya, demikian pula sebaliknya
Pengaruh Kecemasan Komunikasi Terhadap Intensitas Penggunaan Media Sosial Pada Individu Di Usia Emerging Adulthood
Authors: Wigati Dewinta Galih , Nurhayati Siti Rohmah
Published: November 2021

Penelitian ini bertujuan untuk mengetahui pengaruh antara kecemasan komunikasi dengan intensitas penggunaan media sosial pada individu usia emerging adulthood. Penelitian dilakukan di provinsi Daerah Istimewa Yogyakarta dengan menyebarkan kuesioner kepada responden secara online melalui google form. Pengambilan sampel pada penelitian ini menggunakan metode accidental sampling dan mendapatkan 400 responden. Alat pengumpulan data menggunakan skala kecemasan komunikasi dan skala intensitas penggunaan media sosial. Analisis data penelitian ini dilakukan dengan cara uji regresi linier sederhana. Hasil penelitian menunjukkan bahwa kecemasan komunikasi mampu memprediksi intensitas penggunaan media sosial (F=93,337; α=0,000; p0,05). Kecemasan komunikasi dapat memprediksi intensitas penggunaan media sosial dengan nilai kontribusi sebesar 19%. Garis persamaan regresi yang didapat yaitu Y = 44,745 + 0,154X.
Strategi Coping Pada Mahasiswa Ditinjau Dari Big Five Personality
Authors: Lestari Risqa Fuji
Published: November 2021

Penelitian ini bertujuan untuk mengetahui hubungan kepribadian dan strategi coping jenis problem-focused coping (PFC) dan emotion-focused coping (EFC). Penelitian ini mengambil sampel 422 mahasiswa di Universitas Negeri Yogyakarta. Pengambilan sampel dilakukan dengan teknik multi stage random sampling. Pengumpulan data dalam penelitian ini dilakukan dengan menggunakan skala COPE Inventory dan Big Five Inventory. Hasil penelitian menunjukkan bahwa strategi coping PFC maupun strategi coping EFC berhubungan dengan semua tipe kepribadian. Hal tersebut ditunjukkan dengan adanya hubungan positif antara stategi coping PFC mupun strategi coping EFC dengan tipe kepribadian extraversion, agreeableness, conscientiousness, neuroticism, dan openness dengan nilai signifikansi p0,05. Hal ini menunjukkan bahwa strategi atau cara seseorang menyelesaikan masalah baik dengan menghadapi masalah ataupun menggunakan emosi berhubungan positif dengan semua tipe kepribadian.
Pengaruh Kontrol Diri Terhadap Intensitas Penggunaan Smartphone Pada Remaja
Authors: Nurningtyas Fernita , Ayriza Yulia
Published: November 2021

Penelitian ini bertujuan untuk mengetahui pengaruh kontrol diri terhadap intensitas penggunaan smartphone pada remaja. Adapun pendekatan yang digunakan ialah pendekatan kuantitatif dengan jenis penelitian ex post facto. Penelitian ini dilakukan di Kota Yogyakarta dengan subjek penelitian remaja berusia 15-18 tahun dan sampel berjumlah 384 remaja yang diambil dengan menggunakan teknik incidental sampling. Pengumpulan data dilakukan dengan menggunakan metode kuisioner. Instrumen data yang digunakan  adalah skala kontrol diri dan skala intensitas penggunaan smartphone. Validitas instrumen dilakukan dengan menilai validitas isi melalui expert judgment. Pengujian reliabilitas instrument dilakukan menggunakan alpha Cronbach dan menunjukkan nilai koefisien 0,908 pada skala kontrol diri. Teknik analisis data pada penelitian ini menggunakan regresi linear sederhana. Hasil penelitian menunjukkan bahwa terdapat pengaruh kontrol diri secara negatif dan signifikan terhadap intensitas penggunaan smartphone pada remaja usia 15-18 tahun di Kota Yogyakarta (β = -0,102, p0,01) yang artinya kontrol diri mampu menjadi prediktor terhadap intensitas penggunaan smartphone.
Looking out for one another
First Responder Physiological Monitoring (Preprint)
Authors: Anderson Martin
Published: November 2021

UNSTRUCTURED

The pandemic had shed light on healthcare burnout and stress throughout the healthcare workforce even more so the First Responder.

First responders experience significant physiological stress during response operations and face exposure to a myriad of hazards. Miniaturized, wearable sensors attached to or carried by respond- ers can provide incident command with information about an in- dividual’s health status and specific threats and hazards at the in- cident scene. Improved awareness of these factors helps incident command make decisions that increase the safety of responders and the population.

Blended with new advancements in the internet of things and remote care, we are best to look out for one another. Rapid response services like the physician response service at Barts Health NHS trust in east London can offer a new model of working we’re we can look after one another.
A Self-management SMS Text Messaging Intervention for People With Inflammatory Bowel Disease: Feasibility and Acceptability Study (Preprint)
Authors: Rohde Jacob A , Fisher Edwin B , Boynton Marcella H , Freelon Deen , Frohlich Dennis O , Barnes Edward L , Noar Seth M
Published: November 2021

BACKGROUND

Mobile health technologies can be useful for providing disease self-management information and support to people with inflammatory bowel disease (IBD).

OBJECTIVE

The aim of this study was to test a self-management SMS text messaging intervention for people with IBD. Our goal was to examine intervention feasibility, acceptability, and engagement and to preliminarily evaluate improvements in certain self-reported health outcomes among participants.

METHODS

We developed an SMS text messaging program called Text4IBD. The program sent daily support messages and resources about disease self-management over the course of a 2-week, single-group, pretest-posttest intervention to participants (N=114) diagnosed with IBD. We examined intervention feasibility, acceptability, and engagement through Text4IBD message topic recall and use of resources (ie, visiting supplemental websites recommended by the Text4IBD program). We also assessed pretest-posttest measures of IBD-related distress, self-efficacy, perceived support, use of coping strategies, and medication adherence. Analyses examined participants’ evaluations of the intervention and compared pretest-posttest changes in secondary outcomes using paired-samples statistics.

RESULTS

Approximately all participants who completed the intervention (n=105) were receptive to Text4IBD and viewed the program as feasible and acceptable. In addition, most participants (103/105, 98.1%) recalled at least one of the message topics sent by the program, and 79% (83/105) of them self-reported engaging with at least one of the external self-management resources recommended by the Text4IBD program. Pretest-posttest results showed reduced IBD-related distress (mean 3.33, SD 0.68 vs mean 2.86, SD 0.73; P<.001) and improvements in most other secondary outcomes.

CONCLUSIONS

Findings from this study highlight the value of SMS text messaging as a useful digital medium for providing support to people with IBD, particularly to those who may struggle with disease-related distress. Text4IBD was highly feasible and acceptable and may help people self-manage their IBD. Future studies should aim to evaluate this program in a randomized controlled trial in clinical settings.
Readiness to Embrace Artificial Intelligence Among Medical Doctors and Students: Questionnaire-Based Study (Preprint)
Authors: Boillat Thomas , Nawaz Faisal A , Rivas Homero
Published: November 2021

BACKGROUND

Similar to understanding how blood pressure is measured by a sphygmomanometer, physicians will soon have to understand how an artificial intelligence–based application has come to the conclusion that a patient has hypertension, diabetes, or cancer. Although there are an increasing number of use cases where artificial intelligence is or can be applied to improve medical outcomes, the extent to which medical doctors and students are ready to work and leverage this paradigm is unclear.

OBJECTIVE

This research aims to capture medical students’ and doctors’ level of familiarity toward artificial intelligence in medicine as well as their challenges, barriers, and potential risks linked to the democratization of this new paradigm.

METHODS

A web-based questionnaire comprising five dimensions—demographics, concepts and definitions, training and education, implementation, and risks—was systematically designed from a literature search. It was completed by 207 participants in total, of which 105 (50.7%) medical doctors and 102 (49.3%) medical students trained in all continents, with most of them in Europe, the Middle East, Asia, and North America.

RESULTS

The results revealed no significant difference in the familiarity of artificial intelligence between medical doctors and students (P=.91), except that medical students perceived artificial intelligence in medicine to lead to higher risks for patients and the field of medicine in general (P<.001). We also identified a rather low level of familiarity with artificial intelligence (medical students=2.11/5; medical doctors=2.06/5) as well as a low attendance to education or training. Only 2.9% (3/105) of medical doctors attended a course on artificial intelligence within the previous year, compared with 9.8% (10/102) of medical students. The complexity of the field of medicine was considered one of the biggest challenges (medical doctors=3.5/5; medical students=3.8/5), whereas the reduction of physicians’ skills was the most important risk (medical doctors=3.3; medical students=3.6; P=.03).

CONCLUSIONS

The question is not whether artificial intelligence will be used in medicine, but when it will become a standard practice for optimizing health care. The low level of familiarity with artificial intelligence identified in this study calls for the implementation of specific education and training in medical schools and hospitals to ensure that medical professionals can leverage this new paradigm and improve health outcomes.
Association of comorbidities with COVID-19 infection rate and severity: a nationwide cohort study with propensity score matching (Preprint)
Authors: Kim Jiyong , Park Seong Hun , Kim Jong Moon
Published: November 2021

BACKGROUND

Confirming the relationship between comorbidities and coronavirus infection-19 (COVID-19) is important for efficient use of medical facilities.

OBJECTIVE

This study investigated the impact of patient demographics and comorbidities on the infection rate and severity of COVID-19.

METHODS

Data were derived from a Korean nationwide cohort study with propensity score matching. We included 8070 individuals with positive covid-19 test and 12015 controls between January 1, 2020, and May 30, 2020. Outcomes were confirmation of the comorbidities affecting the infection rate and the severity of COVID-19. Endpoints were COVID-19 positivity and severe clinical outcomes of COVID-19 (tracheostomy, continuous renal replacement therapy, intensive care unit admission, ventilator use, cardiopulmonary resuscitation, or death).

RESULTS

In people aged 60 or older, in those insured with Medicaid, and in the disabled, the proportion corresponding to the severe group of patients showed a tendency to increase. The infection rate of COVID-19 was highest in pulmonary disease (adjusted odds ratio 1.88, 95% confidence interval 1.70 to 2.03), and hyperlipidemia (0.73, 0.67 to 0.80) had a lower infection rate. Disease severity was highest in kidney disease (5.59, 2.48 to 12.63), and lower in hyperlipidemia (0.78, 0.60 to 1.00).

CONCLUSIONS

Using propensity matching to reduce statistical bias, we found that most comorbidities increased the infection rate and severity of COVID-19, whereas hyperlipidemia reduced the rate and severity of infection.

INTERNATIONAL REGISTERED REPORT

RR2-https://doi.org/10.1101/2021.09.22.21263946
Impact analysis of expanding narrow-spectrum antibiotic use for children with ear, sinus and throat infections
Authors: Barbosa Carolina , Breck Andrew , King Grant , Bass Sarah , Kook Yoojin , Honeycutt Amanda , Esposito Dominick
Published: November 2021

Aim:Estimate the impacts treating acute respiratory tract infections (ARTIs) in children aged 6 months through 12 years with narrow-spectrum antibiotics.Materials & methods:Decision-tree model to estimate children’s health, healthcare utilization and costs, and caregiver’s time and costs for using narrow-spectrum antibiotics in eligible children with an ARTI, compared with current use of narrow- and broad-spectrum antibiotics.Results:Reduced adverse drug reactions by 35,750 (14%) cases) and 4750 (12%) fewer emergency department visits, 300 (12%) fewer hospitalizations, and 50,500 (10%) avoided outpatient visits. Annual healthcare costs fell by US$120 million (22%). Total societal costs declined by US$131 million (20%).Conclusion:National implementation of narrow-spectrum antibiotics to treat ARTIs in children improves patient outcomes and reduces caregiver burden and annual healthcare costs.
РАЗРАБОТКА ОТЕЧЕСТВЕННОЙ ЭЛЕКТРОННОЙ КОМПОНЕНТНОЙ БАЗЫ СИЛОВОЙ ЭЛЕКТРОНИКИ НА ОСНОВЕ ГЕТЕРОЭПИТАКСИАЛЬНЫХ СТРУКТУР НИТРИДА ГАЛЛИЯ
Authors: Ерофеев Е.В. , Полынцев Е.С.
Published: November 2021

В данной статье представлены результаты разработки отечественных силовых транзисторов и диодов с барьером Шоттки на основе гетероэпитаксиальных структур нитрида галлия. Представлены электрические характеристики разработанных изделий в бескорпусном исполнении по постоянному току.
ЭЛЕКТРОПРОВОДЯЩИЕ СЕТИ НА ОСНОВЕ УГЛЕРОДНЫХ НАНОТРУБОК И ОКСИДА ГРАФЕНА, СФОРМИРОВАННЫЕ ЛАЗЕРОМ
Authors: Куксин А.В. , Герасименко А.Ю.
Published: November 2021

Разработана технология формирования электропроводящих трехмерных сетей из многостенных углеродных нанотрубок и восстановленного оксида графена на кремниевой подложке. Сети формировались в результате наносварки частиц оксида графена и нанотрубок под действием лазерного излучения. Исследованы структурные характеристики, твердость и электропроводность полученных сетей.
РАЗРАБОТКА СПЕЦИАЛИЗИРОВАННОЙ МИКРОСХЕМЫ ЭНЕРГОНЕЗАВИСИМОЙ ПЕРЕПРОГРАММИРУЕМОЙ ПАМЯТИ SONOS
Authors: Ермаков И.В. , Зубов И.А. , Нуйкин А.В. , Алферов В.А.
Published: November 2021

Представлены результаты разработки функциональных блоков микросхемы энергонезависимой электрически программируемой памяти SONOS для специальных применений, выполненной в КМОП-технологии уровня 180 нм.
ВЛИЯНИЕ ЭФФЕКТОВ СТАРЕНИЯ НА ЭЛЕКТРИЧЕСКИЕ ХАРАКТЕРИСТИКИ ИНТЕГРАЛЬНЫХ КМОП ОУ ПРИ УМЕНЬШЕНИИ МИНИМАЛЬНЫХ РАЗМЕРОВ ТРАНЗИСТОРОВ
Authors: Харитонов И.А. , Белопашенцев А.С.
Published: November 2021

С использованием расширенных возможностей SPICE-моделирования КМОП-схем даны количественные оценки усиления влияния эффектов горячих носителей на характеристики КМОП ОУ при уменьшении минимальных размеров транзисторов от долей микрометров до 30 нм.
ФИЗИЧЕСКОЕ МОДЕЛИРОВАНИЕ ЭКСТРЕМАЛЬНЫХ СОБЫТИЙ ПРИ ВЗАИМОДЕЙСТВИИ ОДИНОЧНЫХ ЗАРЯЖЕННЫХ ЧАСТИЦ С МАТЕРИАЛОМ СОВРЕМЕННЫХ ИНТЕГРАЛЬНЫХ МИКРОСХЕМ
Authors: Галимов А.М. , Короченко Д.И. , Гуков А.И. , Фатеев И.А.
Published: November 2021

В докладе представлены результаты моделирования ядерного взаимодействия одиночных заряженных частиц с материалом микросхемы. Показано, что вторичные частицы от данного типа взаимодействия могут повлиять на эффективность систем парирования сбоев в интегральных микросхемах.
ОСОБЕННОСТИ ПРОЕКТИРОВАНИЯ И МОНТАЖА СИСТЕМ РАСПРЕДЕЛЕНИЯ ДЕИОНИЗОВАННОЙ ВОДЫ В СТАНЦИЯХ ВОДОПОДГОТОВКИ ДЛЯ ПРЕДПРИЯТИЙ ЭЛЕКТРОННОЙ ОТРАСЛИ
Authors: Сафонова Д.А.
Published: November 2021

Рассмотрены общие моменты проектирования и монтажа систем распределения деионизованной воды в станциях водоподготовки для предприятий электронной отрасли, даны особенности в зависимости от марки деионизованной воды, определены позиции, влияющие на бюджет и сроки оснащения.
ИНТЕГРАЛЬНЫЕ МИКРОСХЕМЫ. ПРОБЛЕМА ДОВЕРЕННОСТИ
Authors: Безродный Б.Ф. , Беспалов А.В. , Смирнов Д.О.
Published: November 2021

Предложен эффективный способ выявления несанкционированных изменений в конструкции интегральных микросхем, сочетающий преимущества разрушающего и неразрушающего методов контроля.
pedagogia universitária e a formação de professores para a educação básica
Authors: Giareta Paulo Fioravante , Paula Beatriz Mussio Magalhães de , Ribeiro Flávia Moreira Ribeiro
Published: November 2021

Este artigo indica algumas aproximações teóricas quanto às possibilidades e desafios para a consolidação de uma pedagogia universitária para a formação dos profissionais do magistério para atuar na Educação Básica. Metodologicamente, está vinculado à concepção dialética histórica, com aporte na técnica de Análise de Conteúdo (BARDIN, 2002). A pesquisa indica para as conquistas teórico-metodológicas no âmbito da produção de pesquisa sobre a pedagogia universitária no contexto da educação superior brasileira e para as dificuldades de superação das características da experiência histórica de pedagogia universitária no Brasil, configurando um cenário de disputa entre as conquistas pedagógicas atuais e a tradição técnico-profissionalizante, fragmentada e utilitária da educação superior.
Escolas saudáveis: o papel do território educativo no contexto da pandemia de Covid-19
Authors: Demuth Mariana Campos , Faria Ana Beatriz Goulart de , Pompeia Anna Ayumy Inoue , Clasen Carolina Mesquita , Laub Debora , Viola Gabriela Gerotto , Ribeiro Heloisa Bento
Published: November 2021

A presente reflexão foi produzida a partir da experiência de elaboração do Manual Técnico para Escolas Saudáveis, desenvolvido em agosto de 2020 pelo GT Cidade, Infâncias e Juventudes do IAB-SP que, ao descrever as medidas necessárias para um ambiente escolar saudável em um momento de pandemia, coloca em evidência problemas estruturais mais amplos das escolas públicas da rede estadual de São Paulo. Na investigação acerca do que torna uma escola saudável, surge ainda uma pergunta anterior: o que é, afinal, um espaço saudável? O que está por trás desta concepção? A partir disso, revisitando questões que emergem da construção coletiva de um espaço de educação saudável em sua totalidade - incluindo edifício, território, currículo e gestão -, é proposto um levantamento dos fatores que, para além da arquitetura, envolvem a saúde não apenas dos espaços escolares, mas também das experiências corpóreas entre escola, sua comunidade e o território do qual faz parte.
A Rede EPT na perspectiva inclusiva: uma revisão sistemática da literatura sobre formação continuada docente
Authors: Pinheiro Volante Daniele , Ugalde da Costa Luana , Rodrigues Leite Cordeiro Suammy Priscila
Published: November 2021

Trata-se de revisão sistemática de pesquisas que objetivou analisar trabalhos que relacionem formação continuada docente (FCD) e inclusão de estudantes com deficiência (EcD) no ensino técnico integrado ao ensino médio dos Institutos Federais (IFs). A pesquisa justifica-se pela composição dos corpos docentes nos IFs, pelo descompasso entre o acesso dos EcD e a formação docente, e pela escassez de pesquisas sobre o tema. Foram utilizados o Portal de Periódicos da Capes, a Biblioteca Digital Brasileira de Teses e Dissertações e a plataforma Google Acadêmico na busca, resultando em dez publicações que evidenciaram: a escassez de pesquisas, distribuídas em sete dos 38 IFs, a concentração de resultados em 2017 e no IFRN; e a percepção de descompasso entre o discurso sobre educação inclusiva nos documentos institucionais e a prática possível nas instituições como motivação comum aos achados. Por fim, os resultados e conclusões evidenciaram a necessidade de fortalecimento e oferta contínua da FCD nos IFs, para a consolidação de uma educação inclusiva efetiva a todos os estudantes, e de aumento das pesquisas de mesmo tema para enriquecimento e divulgação de conhecimento na área da educação especial em uma perspectiva inclusiva.
A construção de Planos de Ensino Individualizados (PEIs) em um colégio de aplicação: trajetória e desafios
Authors: Araujo Camila Camilozzi Alves Costa de Albuquerque , Caldeira Maria Carolina Da Silva , Alves Ana Luísa
Published: November 2021

Este artigo tem como objetivo analisar o processo de construção de Planos de Ensino Individualizados (PEIs) no Centro Pedagógico (CP/UFMG), colégio de aplicação que oferta o ensino fundamental em tempo integral, com reserva de vagas para estudantes público-alvo da educação especial (PAEE). O PEI é um documento para registrar o processo de inclusão de educandos que demandem adaptações curriculares, sejam eles estudantes PAEE ou não, bem como para traçar as metas específicas de aprendizagem, os avanços e as dificuldades vivenciadas no contexto inclusivo. Com base na perspectiva da educação inclusiva e nas contribuições de Tannús-Valadão; Mendes (2018) e Poker (2013), pretende-se mostrar como o processo de discussão desses Planos tem se dado no Colégio, no período de 2014 a 2021, evidenciando os modos como eles são ressignificados na instituição e os embates que envolvem a construção desse documento. Para isso, foram utilizadas três estratégias metodológicas: pesquisa bibliográfica, pesquisa documental e grupo focal. As análises indicam um processo constante na escola de reflexões a respeito do PEI, bem como desafios quanto à construção de um modelo adequado às demandas da instituição. Mostram também a necessidade de consolidação do trabalho coletivo para a produção desse documento e sua efetivação na prática.