bluuebunny/crossref_metadata_2025 huggingface dataset:
KOMPARATIVNA ANALIZA PROCESA UPRAVLJANJA KORISNICIMA U ORGANIZACIJI
Authors: Grbić Srđan
Published: August 2020

Cilj ovog rada jeste predstav­ljanje teorijskih osnova koncepta upravljanja odnosima sa korisnicima (CRM), kao i vršenje uporedne analize vezane za određene elemente CRM koncepta u dve orga­nizacije, na osnovu dobijenih rezultata istraživanja.
G2C 3G CLICK IoT TERMALNA STANICA
Authors: Jovanov Zoran
Published: August 2020

U ovom radu predstavljena je imple­mentacija rešenja mobilnog uređaja za slanje podataka o temperaturi i vlažnosti vazduha na Cloud. Sistem se sastoji od razvojnog sistema Fusion for ARM v8 koji na sebi sadrzi MCU CARD for STM32, koji služi za komuni­ciranje sa click-ovima i upravljanje istim. Za konekciju s network-om je korišćen  G2C 3G click, koji na sebi sadrži GSM modul i MCU sa instaliranim firmware-om koji komunicira sa modulom i upravlja njime. Za merenje temperature i vlažnosti vazduha je korišćen je Temp&Hum 11 click [1].
МИКРОФЛУИДНИ ЧИП ЗА ДЕТЕКЦИЈУ РАЗЛИЧИТИХ ЛЕКОВА
Authors: Ћоћић Катарина , Стојановић Горан
Published: August 2020

Фалсификовани лекови су велики проблем данашњице, а комерцијално доступне методе за анализу лекова имају одређена ограничења. У циљу истраживања нових техника испитивања и анализе лекова, а за потребе овог мастер рада, развијена је микрофлуидна платформа са сребрним електродама. Направљена је комбинацијом три технике фабрикације. Предложена микрофлуидна платформа се може користити за разликовање правих и лажних лекова на основу измерених вредности електричних параметара, као што су отпорност или капацитивност сребрних електрода
Children with chronic-refractory autoimmune cytopenias: a single center experience
Authors: Karapınar Tuba Hilkay , Töret Ersin , Köker Sultan Aydın , Serdaroğlu Erkin , Gözmen Salih , Genel Ferah , Ay Yılmaz , Gülez Nesrin , Oymak Yeşim , Durgun Ersin , Vergin Canan
Published: August 2020

Background and Objectives. Autoimmune cytopenias are a group of heterogeneous disorders characterized by immune-mediated destruction of one or more hematopoietic lineage cells. The differential diagnosis of children with autoimmune cytopenias requires much time and laboratory investigations. The aim of the present study was to evaluate the clinical course and significance of autoimmune cytopenias due to immunodeficiency or autoimmune diseases in children at a single children`s hospital.
Method. Between February 1997 and September 2015, chronic/refractory autoimmune cytopenias patient data were evaluated retrospectively. Twenty-three patients were assessed in this study.
Results. The median duration of following was 2.6 years (4 months-18.5 years). The median age of diagnosis was 3.1 years (6 months-16 years). A total of 13 patients (56.5%) had single-lineage and 10 (46.5%) had multilineage cytopenias. The most frequent single-lineage cytopenia was thrombocytopenia, followed by anemia. In 22 of the patients, cytopenias was detected before the primary diseases. All of the patients were treated with corticosteroids or intravenous immune globulin as first-line treatment. Ten patients (43.5%) needed second or further-line immunosuppressive therapies that patients diagnosed as systemic lupus erythematosus, hypogammaglobulinemia, or common variable immunodeficiency. A total of 8 patients (34.7%) recovered from autoimmune cytopenias after the treatment of primer disease. Cytopenias were continued in 14 patients.
Conclusion. Cytopenia may be the first finding of an immunodeficiency or autoimmune disease and primary disease may be diagnosed in the clinical course. Taking the new targeted treatment options into consideration; early diagnosis is likely to become more important in the near-future in order to begin the treatment for the underlying disease as early as possible.
Bleeding characteristics and management of minor surgeries in rare bleeding disorders: report from a Turkish Pediatric Hematology Center
Authors: Gelen Sema Aylan , Sarper Nazan , Zengin Emine
Published: August 2020

Background and Objectives. In this retrospective report the aim was to present the experience about bleeding characteristics and management of minor surgeries in rare bleeding disorders (RBDs).
Methods. Twenty-six patients were included; with Factor (F) V, FV+VIII, VII, FXI deficiency and afibrinogenemia. Six of the patients were asymptomatic.
Results. Fifty-three percent of the patients suffered from mucosal bleeding. Life-threatening bleedings were observed only in the patients with afibrinogenemia and good hemostatic control could only be provided with plasma-derived (pd)-fibrinogen concentrate. Twelve of the patients had undergone 17 minor surgeries. In the patients with FVII and FXI deficiencies with plasma F:C activity between 20-47%, there was a history of uneventful tooth extractions, circumcisions and a pilonidal sinus operation performed without any replacement treatment, whereas one patient with plasma F:C activity of FVII 47% had a history of poor hemostatic control during an adeno-tonsillectomy operation. Although some of these patients were asymptomatic to be on the safe side, minor operations were performed with preoperative administration of one dose of (pd)-fibrinogen concentrate to one afibrinogenemia patient, recombinant active FVII (rFVIIa) to 2 FVII deficient patients and fresh frozen plasma (FFP) to 3 FXI deficient and 1 FVII deficient patients plus postoperatively tranexamic acid (TXA) for 5-7 days. Only with one dose of the replacement therapy just before surgeries good hemostatic control was achieved and none of them had bleeding neither during nor after the surgeries.
Conclusion. We suggest that minor operations must be performed with preoperative replacement therapies plus 5-7 days of antifibrinolytics under close observation of the hematologist and the surgeon.
Neuropsychological outcome in cases with acute disseminated encephalomyelitis
Authors: Kanmaz Seda , Erermiş Hatice Serpil , Tekgül Hasan , Aktan Gül , Yılmaz Sanem , Serin Hepsen Mine , Şimşek Erdem , Eraslan Cenk , Köse Sezen , Gökben Sarenur
Published: August 2020

Background and Objectives. Acute disseminated encephalomyelitis (ADEM) is an immune-mediated, inflammatory and demyelinating disorder of the central nervous system. There have been a few studies in recent years on the fact that these cases have neurocognitive impairment. The purpose of this study is to evaluate the neurocognitive outcome and quality of life in cases with ADEM.
Methods. Eleven cases who were on follow-up between 2008 and 2017 were included in the study, systemic, neurological and psychiatric examinations were done. All magnetic resonance images were re-evaluated. The neuropsychiatric evaluation was performed by clinical examination and psychometric scales; (1) The Pediatric Quality of Life Inventory 4.0, (2) Child Behavior Checklist, (3) Children`s Depression Inventory, (4) The Wechsler Intelligence Scale for Children-Revised and (5) Continuous Performance Test. The cases in our study underwent neuropsychiatric evaluation 3-42 months after the diagnosis of ADEM had been established.
Results. Nine cases (81.8%) fully recovered without neurologic deficit. One case (9.1%) had a psychiatric disorder. During follow-up, cognitive and psychiatric problems were encountered in half of the cases (54.5%). Most of the cases with basal ganglia involvement (80%) displayed attention deficit and cognitive problems.
Conclusion. In particular, cases with basal ganglia involvement should be followed carefully in terms of attention and cognitive problems.
Two patients with glutaric aciduria type 3: a novel mutation and brain magnetic resonance imaging findings
Authors: Dorum Sevil , Havalı Cengiz , Görükmez Özlem , Görükmez Orhan
Published: August 2020

Background. Glutaric Aciduria Type 3 (GA-3) is a rare metabolic disease which is inherited autosomal recessively and characterized by isolated glutaric acid excretion. To date, a limited number of cases have been reported in the literature. We present two patients with GA3 who were diagnosed with the isolated increased level of glutaric acid in urine.
Case. Glutaric aciduria type 1 and type 2 were excluded by genetic analysis and other laboratory and clinical findings. One of our patients had a homozygous mutation p.Arg322Trp (c.964C > T) of SUGCT (NM_001193311) gene. To the best of our knowledge this mutation has not been reported in the literature previously. Symmetrical periventricular and deep cerebral white matter abnormalities were detected on his brain magnetic resonance imaging (MRI).
Conclusion. We present two patients with GA-3 and a novel mutation in the SUGCT gene. Our findings expand the spectrum of causative mutations and clinical findings in GA-3.
Extracorporeal shock wave lithotripsy in the management of a 14-year-old girl with chronic calcific pancreatitis
Authors: Türer Özlem Boybeyi , Soyer Tutku , Parlak Erkan , Özcan Hatice Nursun , Bilen Cenk Yücel , Tanyel Feridun Cahit
Published: August 2020

Background. Chronic pancreatitis is very rare in childhood and causes chronic/relapsing abdominal pain, frequent hospitalizations, malnutrition, growth retardation, and stone formation in the main duct. Although pancreatic extracorporeal shock wave lithotripsy (P-ESWL) is commonly used in the treatment of pancreatic stones (PS) in adults, the use in children is still controversial. An adolescent girl with multiple PS is presented to discuss the use of ESWL as a treatment alternative in children with PS.
Case. A 14-year-old girl was admitted with abdominal pain and elevated pancreatic enzyme levels. Abdominal US showed irregularity and rough echogenicity in pancreas revealing pancreatitis. Multiple stones were seen in main pancreatic duct on Magnetic resonance cholangiopancreatography (MRCP). Endoscopic retrograde cholangiopancreatography (ERCP) was performed and dilated pancreatic duct, thickened pancreatic secretion were detected. Endoscopic sphincterotomy was performed. Endoscopic removal of stones could not be achieved since the largest stone was 17x8 mm. Pancreatic extracorporeal shock wave lithotripsy (P-ESWL) was performed using electromagnetic lithotripter under general anesthesia. Following ESWL, fragmentation of stones in the main duct was confirmed with ERCP. After 3 sessions of ESWL, no ESWL-related complication was observed. Pain relief was achieved. The patient is still under follow-up regarding endocrine and exocrine function of pancreas.
Conclusion. ESWL may be an effective and safe management option in pediatric PS which could not be removed by ERCP. The patients managed with ESWL should be followed-up for a long time regarding the endocrine and exocrine functions of the pancreas. As in management of adult pancreatitis, clinical guidelines are needed regarding the management of pediatric PS.
Efek Intervensi Perilaku Terhadap Manajemen Diri Penderita Diabetes Melitus Tipe 2: Sistematik Review
Authors: Haskas Yusran , Suarnianti Suarnianti , Restika Indah
Published: August 2020

Behavioral intervention sangat penting dilakukan dalam manajemen diri penderita Diabetes Melitus tipe 2 sebagai intervensi dalam upaya meningkatkan status kesehatan. Manajemen diri merupakan hal penting untuk mempertahankan kontrol gula darah sehingga komplikasi pada penderita DM tipe 2 dapat dicegah. Tujuan: Mengetahui bentuk intervensi perilaku untuk mengukur outcome dari manejemen diri penderita DM tipe 2. Metode:  Electronic database dari jurnal yang telah dipublikasi melalui Google Schoolar, ProQuest, PubMed., dan ScienceDirect. Hasil review dari 8 jurnal yang telah dipilih menyatakan bahwa behavioral intervention memberi pengaruh terhadap manajemen diri penderita DM tipe 2 dalam kontrol glikemik. Instrumen penelitian yang  digunakan untuk mengukur behavioral intervention pada penelitian kuantitaif yakni kuesioner, melakukan observasi perubahan perilaku, sedangkan pada penelitian kualitatif menggali informasi dengan indepth interview. Hasil: Efek behavioral intervention yang meliputi pemberian edukasi dan self efficacy dapat memfasilitasi peningkatan pengetahuan, pencegahan komplikasi dan meningkatkan kualitas hidup pasien DM tipe 2. Simpulan: efek behavioral intervention sangat efektif dalam meningkatkan manajemen diri penderita DM tipe 2, namun pelaksanaan intervensi perlu dimodifikasi agar didapatkan hasil yang lebih maksimal, salah satunya dengan pemanfaatan terknologi berbasis komunitas.Kata kunci: behavioural intervention, diabetes melitus tipe 2, manajemen diri
ПЛІВКИ МЕДИЧНОГО ПРИЗНАЧЕННЯ НА ОСНОВІ ПОЛІСАХАРИДІВ
Authors: Ishchenko Olena
Published: August 2020

Актуальність теми дослідження визначається необхідністю розробки сучасної вітчизняної технології створення біоактивних полімерних матеріалів для трансдермальних систем та надання їм комплексу властивостей, зокрема знеболювальних та антимікробних. Дослідження набувають актуальності також з урахуванням того, що склади плівок на основі полісахаридів мають певні переваги. Також доступна вітчизняна первинна сировина для їх одержання. Постановка проблеми. Встановити можливість та особливості одержання плівок медичного призначення на основі хітозану та крохмалю. Аналіз останніх досліджень і публікацій. Були розглянуті останні публікації у відкритому доступі стосовно
полімерних матеріалів, які використовують для одержання сучасних лікарських засобів, таких як плівки, губки, гелі з антисептичними та фунгіцидними властивостями. Виділення недосліджених частин загальної проблеми. Технології одержання плівки на основі композиції хітозану та крохмалю з покращеними фізико-механічними властивостями. Постановка завдання. Розробити технологію та композиції для одержання плівок на основі полісахаридів, а саме: хітозану, розчиненого в 5 %-вій молочній кислоті, та крохмалю з різними масовими частками, дослідити одержані плівки, встановити придатність цих матеріалів для застосування як плівок медичного призначення. Виклад основного матеріалу. Встановлено, що полімерна композиція на основі хітозану та крохмалю, за другим
способом підготовки, мають покращені фізико-механічні властивості, розривна напруга зростає з 0,38 до 1,64 МПа. Встановлено, що процес термостабілізації та збільшення вмісту крохмалю впливають на сорбційні властивості плівок, які поступово зменшуються від 300 до 110 %, і це дає можливість регулювати кінетику вивільнення. Висновки відповідно до статті. У результаті проведених досліджень встановлено, що запропонована технологія та рецептурний склад плівок на основі полісахаридів може бути застосовано для одержання плівок медичного призначення. Процесом термостабілізації та вмістом крохмалю можна регулювати сорбційні властивості плівок і це вливає на кінетику вивільнення лікарського препарату
Línguas indígenas da Amazônia: uma diversidade ameaçada
Authors: Souza Marina Mello de Menezes Felix de , Bastos Hugo Bertha
Published: August 2020

Em meio a uma pandemia mundial gerada pela proliferação da Covid-19, o Professor Doutor José Ribamar Bessa Freire pensa a vulnerabilidade histórica das comunidades indígenas e a importância de pensarmos as glotopolíticas brasileiras. Dessa forma, por meio de um panorama histórico, Freire nos faz refletir sobre as decisões político-linguísticas estimuladas pela Coroa Portuguesa e no quanto elas se encontravam intimamente ligadas à interesses geopolíticos e econômicos. No passado, tais decisões governamentais alteram o destino de diversas línguas e culturas, desencadeando processos de deslocamentos linguísticos que culminaram no seu completo desaparecimento. Assim, a fala de Freire suscita a necessidade do debate acerca dos interesses envolvidos em se estabelecer políticas prejudiciais aos povos autóctones, do futuro da diversidade linguística brasileira e do impacto de recentes negligências governamentais.
Pressure Induced Topochemical Polymerizationof Solid Acryalmide Facilitated by Anisotropic Response of Hydrogen Bond Network
Authors: Maiti Sayan , Gangan Abhijeet Sadashiv , Anshu Ashwini , Valappil Rashid Rafeek V. , Chakraborty Brahmananda , Ramaniah Lavanya M. , Srinivasan Varadharajan
Published: August 2020

The pressure induced polymerization of molecular solids is an appealing route to obtain pure, crystalline polymers without the need for radical initiators. Here, we report a detailed density functional theory (DFT) based study of the structural and chemical changes that occur in defect free solid acrylamide, a hydrogen bonded crystal, when it is subjected to hydrostatic pressures. Our calculations predict a polymerization pressure of 94 GPa, in contrast to experimental estimates of 17 GPa, while being able to reproduce the experimentally measured pressure dependent spectroscopic features. Interestingly, we find that the two-dimensional hydrogen bond network templates a topochemical polymerization by aligning the atoms through an anisotropic response at low pressures. This results not only in conventional C-C, but also unusual C-O polymeric linkages, as well as a new hydrogen bonded framework, with both NH... O and C-H...O bonds.
Thermochromic AIE Dual Phosphorescence via Temperature-Dependent sp3-Linked Donor-Acceptor Electronic Coupling
Authors: Wang Tao , Hu Zhubin , Nie Xiancheng , Huang Linkun , Miao Hui , Sun Xiang , Zhang Guoqing
Published: August 2020

Aggregation-induced emission (AIE) has proven to be a viable strategy to achieve highly efficient RTP in bulk by restricting molecular motions. Here we show that by utilizing triphenylamine (TPA) as an electronic donor which connects to an acceptor via an sp3 linker, six TPA-based AIE-active RTP luminophores were obtained. Both the TPA AIE-gen and the sp3-linkage can suppress aggregation-caused quenching. Consequently, dual phosphorescence bands emitting from localized donor and acceptor triplet states, respectively, could be recorded at lowered temperatures; at room temperature, only a single RTP band corresponding to the lowest triplet state is present, presumably due to thermally assisted electronic coupling between the two states. The reported molecular construct serves as an “intermediary case” between a fully conjugated donor-acceptor system and a do-nor/acceptor binary mix, which may provide important clues on the design and control of molecular systems with complex excited-state dynamics.
Rapid Prediction of Possible Inhibitors for SARS-CoV-2 Main Protease using Docking and FPL Simulations
Authors: Quan Pham Minh , Vu Khanh B. , Pham T. Ngoc Han , Huong Le Thi Thuy , Tran Linh Hoang , Tung Nguyen Thanh , Vu Van , Nguyen Trung Hai , Ngo Son Tung
Published: August 2020

Appearance for the first time from Wuhan, China, the SARS-CoV-2 rapidly outbreaks worldwide and causes a serious global health issue. The effective treatment for SARS-CoV-2 is still unavailable. Therefore, in this work, we have tried to rapidly predict a list of potential inhibitors for SARS-CoV-2 main protease (Mpro) using a combination of molecular docking and fast pulling of ligand (FPL) simulations. The approaches were initially validated over a set of eleven available inhibitors. Both Autodock Vina and FPL calculations adopted good consistent results with the respective experiment with correlation coefficients of R_Dock=0.72 ± 0.14 and R_W = -0.76 ± 0.10, respectively. The combined approaches were then utilized to predict possible inhibitors, which were selected from a ZINC15 sub-database, for SARS-CoV-2 Mpro. Twenty compounds were suggested to be able to bind well to SARS-CoV-2 Mpro. The obtained results probably lead to enhance COVID-19 therapy.
Emission Color-Tunable Oxazol(in)yl-Substituted Excited-State Intramolecular Proton Transfer (ESIPT)-Based Luminophores
Authors: Göbel Dominik , Rusch Pascal , Duvinage Daniel , Bigall Nadja C. , Nachtsheim Boris
Published: August 2020

Oxazolinyl- and arylchalcogenyl-substituted hydroxyfluorenes exhibiting excited-state intramolecular proton transfer (ESIPT) are described as potent and highly modular luminophores. Emission color-tuning was achived by benzannulation of the oxazline and insertion of different chalcogens.
Charge Accumulation Kinetics in Multi-redox Molecular Catalysts Immobilised on TiO2
Authors: Bozal-Ginesta Carlota , Mesa Camilo A. , Eisenschmidt Annika , Shankar Ravi , Francàs Laia , Antón-García Daniel , Warnan julien , Willkomm Janina , Reynal Anna , Reisner Erwin , Durrant James R
Published: August 2020

Multi-redox catalysis requires the transfer of more than one charge carrier and is crucial for solar energy conversion into fuels and valuable chemicals. In photo(electro)chemical systems, however, the necessary accumulation of multiple, long-lived charges is challenged by recombination with their counterparts. Herein, we investigate charge accumulation in two model multi-redox molecular catalysts for proton and CO2 reduction attached onto mesoporous TiO2 electrodes. Transient absorption spectroscopy and spectroelectrochemical techniques have been employed to study the kinetics of photoinduced electron transfer from the TiO2 to the molecular catalysts in acetonitrile, with triethanolamine as the hole scavenger. At high light intensities, we detect charge accumulation in the millisecond timescale in the form of multi-reduced species. The redox potentials of the catalysts and the capacity of TiO2 to accumulate electrons play an essential role in the charge accumulation process at the molecular catalyst. Recombination of reduced species with valence band holes in TiO2 is observed to be faster than microseconds, while electron transfer from multi-reduced species to the conduction band or the electrolyte occurs in the millisecond timescale. Finally, under light irradiation, we show how charge accumulation on the catalyst is regulated as a function of the applied bias and the excitation light intensity.
Simultaneous Characterization of Lipid sn-Positional and Double-Bond Positional Isomers using On-Demand Electrochemical Mass Spectrometry
Authors: Tang Shuli , Yan Xin
Published: August 2020

We present an on-demand electrochemical mass spectrometry workflow for lipid structural characterization with the capability of identifying double-bond and sn-positional isomers. Two voltage-controlled electrochemical reactions, interfacial electro-epoxidation and anodic corrosion of a cobalt electrode, are cascaded in this strategy. The epoxidized products and Co-adducted ions of lipids are fragmented in tandem MS to generate structure characteristic fragments that indicate double-bond and sn-positions. The unique feature of this workflow lies in the sequential localization of double bonds, elucidation of sn-positions, and collection of native lipid information in a single system and simply by tuning ESI voltages. This feature, as well as low sample consumption, no need for extra apparatus, and quantitative analysis, should allow wide applications in the lipidomic field.
Quantum Machine Learning for Drug Discovery
Authors: Batra Kushal , Zorn Kimberley M. , Foil Daniel H. , Minerali Eni , Gawriljuk Victor O. , Lane Thomas R. , ekins sean
Published: August 2020

The growing public and private datasets focused on small molecules screened against biological targets or whole organisms 1 provides a wealth of drug discovery relevant data. Increasingly this is used to create machine learning models which can be used for enabling target-based design 2-4, predict on- or off-target effects and create scoring functions 5,6. This is matched by the availability of machine learning algorithms such as Support Vector Machines (SVM) and Deep Neural Networks (DNN) that are computationally expensive to perform on very large datasets and thousands of molecular descriptors. Quantum computer (QC) algorithms have been proposed to offer an approach to accelerate quantum machine learning over classical computer (CC) algorithms, however with significant limitations. In the case of cheminformatics, one of the challenges to overcome is the need for compression of large numbers of molecular descriptors for use on QC. Here we show how to achieve compression with datasets using hundreds of molecules (SARS-CoV-2) to hundreds of thousands (whole cell screening datasets for plague and M. tuberculosis) with SVM and data re-uploading classifier (a DNN equivalent algorithm) on a QC benchmarked against CC and hybrid approaches. This illustrates a quantum advantage for drug discovery to build upon in future.
Efficient techniques for postoperative analgesia in laparoscopic cholecystectomy
Authors: Chandana Madhuri T  , Uma Bhanu D  , Mounika P  , Ganesh B  , Shaik Mujafar  , Harika P  , Kameshwari N  , Shaik Faizan Ali
Published: August 2020

Today, in a generation of technological improvements, Laparoscopic cholecystectomy (L.C.) is the selection for the treatment of symptomatic illnesses of gallbladder like cholecystitis and cholelithiasis. Legitimate pain control is essential for advancing scientific outcomes and previous ambulation after surgery. Results aren't suitable for daycare surgeries. It is minimally invasive with much less postoperative ache, rapid recuperation, lesser health facility live and return to everyday interest on the earliest1. Though laparoscopic cholecystectomy is a slightly invasive surgical procedure with more secondary perioperative pain scores assessment to open procedures, it is present with enormous ranges of postoperative ache. The present prospective, unmarried blinded, randomized manipulate study protected sixty patients scheduled for laparoscopic cholecystectomy and aimed to compare the postoperative analgesia between the posterior transversus abdominis plane block and subcostal transversus abdominis aircraft block. The patients were randomly allotted to 2 businesses- Group 1 consisted of patients who received posterior T.A.P. block with zero. 2% Ropivacaine with Dexmedetomidine 1mcg/kg and Group 2 consisted of patients who obtained subcostal T.A.P. block with zero.2% Ropivacaine with Dexmedetomidine 1mcg/kg. All patients underwent laparoscopic cholecystectomy under general anaesthesia. At the quit of the surgical operation earlier than extubation, both one of the blocks were executed on the affected person underneath ultrasound steering by the identical anaesthesiologist. The objectives of the study were to compare the postoperative pain relief based on VAS at rest and VAS at deep breathing, to compare the time taken for the administration of rescue analgesia (duration of analgesia) and to compare the time taken to perform the block.
Concept of Airborne Infectious Disease in Ayurveda
Authors: Madhura Vinay Fadanavis  , Punam Sawarkar
Published: August 2020

Life of any living thing starts with the breath and ends with breathlessness. Health is defined as a state of equilibrium of normal functions of Dosha, Dhatu, and Agni with body, mind and soul. Health has not given importance until someone becomes sick. Due to intake of improper diet, lack of exercise, stress, & global warming, pollution the health status of an individual is decreasing day by day & they are getting easily prone to infectious disease. It comes with significant challenges & creating a burden over medical & health care system. Ayurveda is an ancient science which has already described such communicable disease with their causes, mode of transmission, prevention as well as treatment. Charak has explained about Janapadodhwansa & its four reasons(Air, water, time, and region). Sushruta has already mentioned Aupsargikarogas that are infectious diseases. By adopting Ayurvedic measures such as following proper Dincharaya, Rutucharya, Sadvritta, Panchakarma, Shaman Cikitsa & Rasayana, both physical and mental health, can be maintained. The main aim of this paper is to highlight the airborne disease mentioned in Ayurveda. This review has been done by compiling information from classic Ayurvedic texts – Charak Samhita, Sushruta Samhita, and Astanga Hirdaya. Apart from this, modern books, journals & websites on preventive & social medicine were also searched for this study. After extensive search, specific causative factors, pathology, symptoms & various treatment regime has been narrated in scattered form by our Ancient Acharyas. The different Ayurvedic Samhitas serves as a source of getting knowledge about the airborne disease and ways to prevent it and cure it. By using these basic principles in this ancient science in a rational way, we can avoid & overcome many clinical conditions described in contemporary science which has its self-limitations in treatment modalities.
Risk and the Rule of law
Authors: McLean Janet
Published: August 2020

In this article the author argues for the importance of law even in the face of a global pandemic, suggests some ways that law helps to reveal and articulate the moral issues at stake, and sketches the legal controversies surrounding the Covid-19 lockdown.
Globalisation in the Time of Coronavirus
Authors: Bollard Alan
Published: August 2020

This article considers the effects that the Covid-19 pandemic may have on those aspects of international commerce and trade that are most relevant to New Zealand’s economic future. It covers changes to international political economy and the likely impacts of the huge international policy response. Businesses are starting to trade differently, people no longer cross borders so freely, there is changed use of technology, there are challenges for the financial sector, and governments are taking on new roles and issuing huge amounts of debt. Bilateral trade tensions are becoming more acute. People are going to have to live through disruption and pay for this pandemic.
Health Post-Pandemic
Authors: Davis Peter
Published: August 2020

The Covid-19 pandemic has provided the ultimate stress test of the New Zealand health system, confirming known weaknesses, but also facilitating useful responses and changes. We discovered an effective centre, as well as regional cooperation, and IT enhancements may finally have their day. The financial stress of family doctors revealed our patchwork funding system, and privacy issues in the use of identifiers and matters of jealously guarded scope of practice in the workforce were exercised under pandemic conditions. Hospitals were able to function at 50% capacity, and deficiencies were revealed in the aged care sector. Finally, we avoided gross health inequalities. With a review of the system recently released, this experience may advance the cause of reform.
Transforming the Economy
Authors: Boston Jonathan
Published: August 2020

The global ecological crisis poses much greater risks to humanity than Covid-19. At the same time, the pandemic provides a unique opportunity for governments to pursue a ‘greener’ and more sustainable future, for example through large-scale investments in clean energy sources, energy efficiency, waste reduction technologies, climateresilient infrastructure, regenerative agriculture and biodiversity protection. Yet, despite the urging of leading economists, ecologists and investors, measures to enhance ecological sustainability have not been prioritised in most governmental fiscal and regulatory responses to the pandemic. This article briefly summarises the nature of the current ecological crisis and, with particular reference to New Zealand, the policy measures required for an effective response. Fundamentally, a step change is needed from the current linear economy (based on finite energy sources and other non-renewable natural resources) to a more circular economy (based on renewable energy sources, the minimisation of waste and the efficient use of natural resources).
Support for Workers in the Covid-19 Emergency
Authors: Rosenberg Bill
Published: August 2020

This article first briefly describes pre-Covid-19 support for workers who lose their jobs in New Zealand, then outlines and evaluates the government response to potential and actual job loss in the Covid-19 emergency. The main response was a wage subsidy. Some aspects of it were highly effective; others were problematic and tolerable only because it was a crisis and temporary. It demonstrated the systemic weaknesses in New Zealand’s support for displaced workers. The article finally considers what is needed to prepare New Zealand better for times of job loss.
Financial Inclusion and Determinants in South Asian Countries
Authors: Robina Badar  , Sofia Anwar  , Syed Asif Ali Naqvi
Published: August 2020

Financial inclusion is considered an essential mediator to achieve economic growth in recent years. The main focus of this study is to construct the financial inclusion index and to explore the determinants of financial inclusion in Pakistan, Bangladesh, and India. Data is collected from InterMedia's financial inclusion insights datasets 2016 that are collected through random sampling. The financial inclusion index is used as a dependent variable that is calculated using levels of access and usage of financial services. Age, gender, education, financial situation, working type and use of mobile phones are used as independent variables. Results of multinomial logistic regression reveals that in South Asian countries educated, male, relatively older, rich and regular employees have a better chance to be financially included. Mobile phone users also prefer high financial inclusion. Developing countries like Pakistan, Bangladesh, and India can attain inclusive growth by increasing the contribution of weaker sections of the population with the mainstream. If weaker sections of the population have easy access to financial services, the economic growth of a country can be enlarged. So policymakers should focus on the financial sector's structural problems and pay attention to create modern financial institutes both in the banking sector and in financial markets.
Determinants of tobacco use in Sudan: secondary analysis of STEPwise Survey 2016
Authors: Nur Muna , Wagialla Naiema A. , Eltigany Mai , Elemam Manal , Ibrahim Nazik , Ali Nahid , Hassan Fatima , Hassan Nazik , Nurelhuda Nazik
Published: August 2020

Background: Tobacco is a leading cause of death and illness despite > 50 years of antitobacco efforts. Aims: To establish the determinants of current and former smoking and smokeless tobacco use in Sudan as measured by the STEPwise Survey 2016. Methods: A household-based cross-sectional World Health Organization STEPwise Survey was conducted among 7745 Sudanese citizens aged 18–69 years across 11 states in Sudan. A 4-stage stratified cluster sampling design was implemented. The generic STEPS Instrument (version 3.2) was used and questions were tailored to the Sudanese context. Results: Among current male smokers, 63.7% were aged ≤ 35 years, 50.7% were illiterate or did not complete primary school, 84.5% were employed and 52.4% were in the lowest 2 quintiles of income. Among male smokeless tobacco users, 54.8% were aged ≤ 35 years, 48.4% were illiterate or did not complete primary school, 89.7% were employed and 52.2% were in the lowest 2 quintiles of income. Using multivariate logistic regression models, current smoking in men was associated with older age, informal education, unemployment and lower income. Smokeless tobacco use was associated with age 18–25 years, informal education, unemployment and lower income. Conclusions: Both forms of tobacco use were associated with poor socioeconomic status and unemployment. Smokeless tobacco use was associated with age 18–25 years as opposed to smoking tobacco use. These results can inform the target audience of the future tobacco control plans.
O livro didático de Física e suas tendências: uma análise necessária da influência behaviorista no ensino de Ciências
Authors: Melo Marcos Gervânio de Azevedo , Neves Marcos Cesar Danhoni , Silva Sani de Carvalho Rutz da , Pinheiro Nilcéia Aparecida Maciel , Miquelin Awdry Feisser
Published: August 2020

O trabalho, ora apresentado, tem o objetivo de fazer uma análise de um livro de Física comumente utilizado por professores na rede básica. O livro em questão é o Tópicos de Física 3. Na ocasião, procura-se destacar aspectos behavioristas que aparecem como elementos basilares no conteúdo presente no livro. Assim, buscou-se, no livro didático, encontrar excertos que pudessem se articular a conceitos importantes do Behaviorismo, desde Pavlov e Watson até Skinner. Foi possível observar um grande número de aspectos behavioristas presentes como reforço positivo e reforço negativo, contingência de reforço, entre outros. Diante disso, é possível dizer que o livro Tópicos de Física 3 apresenta uma forte influência behaviorista e que isso pode ser um interessante parâmetro para se levar em consideração no momento de adoção do mesmo pelos professores no ensino de Física.
Conjunto de atividades didáticas de Mecânica baseadas em Resolução de Problemas e simulações computacionais
Authors: Pastorio Dioni Paulo , Vidmar Muryel Pyetro , Alves Josemar , Centenaro Francis Jessé
Published: August 2020

Neste artigo, apresentamos um conjunto de atividades didáticas (AD) de Mecânica, baseadas em Resolução de Problemas (RP) e simulações computacionais (SC). Esse conjunto de AD tem como objetivo abordar os conteúdos conceituais, procedimentais e atitudinais de forma integrada, através da estratégia de Resolução de Problemas proposta por Pozo. Ainda, com o auxílio de simulações computacionais, as atividades buscam munir os estudantes de habilidades e competências em um Ambiente de Computação Numérica (ACN). A análise dos resultados obtidos pela implantação das AD em uma turma de alunos ingressantes de um curso de Meteorologia de uma Universidade Pública, mostrou que a estratégia de RP em Física ainda é uma importante ferramenta de ensino e que a articulação entre essa e o uso de SC, potencializaram o desenvolvimento de competências e habilidades associadas aos conteúdos conceituais e procedimentais, assim como em um ACN, de modo que os principais objetivos puderam ser alcançados, tendo ainda, a partir da análise, potencial para ser generalizada para outras realidades escolares.
Laboratório epistemológico na formação inicial de professores de Física: Aproximações, limites e possibilidades.
Authors: Macedo Sabrinna Aparecida Rezende , Barrio (in memoriam) Juan Bernardino Marques
Published: August 2020

O presente artigo defende a ideia de que, para que sejam melhor contempladas no Ensino Médio as atividades experimentais e as abordagens histórico-filosóficas, antes, é necessário que durante a formação inicial os professores vivenciem estas duas instâncias formativas. Acredita-se, neste trabalho que tais instâncias formativas são capazes de colaborar para a consolidação da personalidade epistemológica dos futuros professores, possibilitando-lhes repensar a experimentação e visualizar as várias possibilidades de abordagens. Este estudo aponta para a possível aproximação entre os laboratórios Tradicional e Epistemológico, desde que ajustadas algumas questões como o tempo das aulas e maior flexibilidade em relação aos procedimentos exigidos no Laboratório Tradicional.
Professora experiente em atividade investigativa sobre a docência no estágio da licenciatura em física
Authors: Rabelo Leandro de Oliveira , Azevedo Maria Nizete de , Abib Maria Lúcia Vital dos Santos
Published: August 2020

Neste trabalho analisamos o caso de uma professora experiente, bacharel em Física, que está cursando a Licenciatura em Física em uma universidade pública brasileira. Focalizamos o seu estágio supervisionado, desenvolvido no âmbito de uma disciplina de Metodologia do Ensino de Física, buscando entender: que fatores contextuais impulsionaram a mudança de sentidos atribuídos pela estagiária-professora ao estágio supervisionado, de modo a realizar com empenho a atividade do estágio curricular supervisionado? Para isso, com base na Teoria Histórico-Cultural da Atividade, analisamos os dados que emergiram do portfólio de estágio entregue pela estagiária-professora e de uma entrevista semi-estruturada, realizada com ela após o término do estágio. Os resultados indicam que inicialmente a estagiária-professora estava pouco mobilizada no estágio. Com o tempo, os seus sentidos em relação ao estágio se alteraram, levando a um forte engajamento no estágio e na disciplina. Alguns fatores foram importantes para essa mudança: a valorização pelos colegas e pela docente da disciplina da sua experiência como professora, o desenvolvimento de um projeto investigativo em docência e a criação de um ambiente de trocas coletivas propiciado pela disciplina da universidade. Esses resultados apontam para as potencializadas da pesquisa em docência para a formação inicial e continuada de professores.
Aprendizagem significativa, objetos de aprendizagem e o ensino de Astronomia
Authors: Voelzke Marcos Rincon , Macêdo Josué Antunes de
Published: August 2020

Esse artigo aborda o uso dos objetos de aprendizagem no ensino de Astronomia, em busca de promover uma aprendizagem significativa, dado que na maioria das vezes seu ensino ocorre de forma estanque e sem conexão com a realidade. O objetivo é apresentar e discutir uma atividade potencialmente significativa para o ensino de Astronomia. Inicialmente faz-se uma discussão sobre aprendizagem significativa, posteriormente aborda-se o uso de objetos de aprendizagem e simulações no ensino de Astronomia. A partir disso, propõe-se uma atividade usando o software Stellarium, utilizando-se a metodologia baseada nos três momentos pedagógicos de Delizoicov e Angotti. Essa atividade aborda a variação do dia claro e da noite nas diferentes estações. Espera-se com isso contribuir com o ensino de Astronomia utilizando-se as tecnologias digitais como forma de facilitar o processo de ensino e aprendizagem dessa área do conhecimento.
A Mode-Matching Solution for TE-Backscattering from an Arbitrary 2D Rectangular Groove in a PEC
Authors: Bozorgi Mehdi
Published: August 2020

In this paper, the simple yet effective mode-matching technique is utilized to compute TE-backscattering from a 2D filled rectangular groove in an infinite perfect electric conductor (PEC). The tangential magnetic fields inside and outside of the groove are represented as the sums of infinite series of cosine harmonics (half-range Fourier cosine series). By applying the continuity of the tangential magnetic field, these modes are matched on the groove to obtain the series coefficients by solving a system of linear equations. For this purpose, some oscillatory logarithmic singular integrals involving Hankel and trigonometric functions are solved numerically, starting by removing the logarithmic singularity via integration by parts. In the following, the new well-behaved highly oscillatory integrals are computed using efficient methods, and several comparisons are made to demonstrate the validity and ability of the presented procedure.
Design and Analysis of a TEM Mode Rectangular Coaxial Waveguide for Mobile 5G Millimeter Wave Antenna Module Applications
Authors: Park Eunyoung , Kim Sangkil
Published: August 2020

In this paper, design and analysis of a transverse electromagnetic (TEM) mode rectangular coaxial waveguide for a mobile 5G millimeter wave (mmWave) antenna module are presented. General structures of 5G radio frequency (RF) module for mobile sub-6 GHz and mmWave applications are also discussed in this paper. Thorough analysis of transmission line and waveguide structures at mmWave frequency band is essential and fundamental information to design highly integrated RF front-end modules. Theoretical design equations of the waveguide, such as impedance, loss, and radiation are presented, and the equations are verified by a full wave 3D FEM electromagnetic simulator. Impedance value of the rectangular waveguide structure was calculated using the conformal mapping method. Theoretical operation frequency bandwidth and design guide are also presented. The characteristics and analysis of the rectangular coaxial waveguide structure presented in this paper is easily scalable to other frequency bands. The proposed design equations are also applicable to various planar layer-by-layer integrated circuit (IC) or module manufacturing process.
Design and Investigation of a Miniaturized Single-Layer ACS-Fed Dual Band Antenna for LTE and 5G Applications
Authors: Gunamony Shine Let , Gnanadhas Josemin Bala , Lawrence Diana Evangeline
Published: August 2020

Presently, a single compact antenna is expected to operate in multiple frequency bands, so that it may be used for multiple applications. In this regard, a compact asymmetric coplanar strip (ACS) fed monopole antenna was designed to operate in LTE band-40 and 5G mid band frequencies. To achieve the desired dual band frequency, meander line radiating structure was used. The uniplanar design with the ACS feed considerably reduced the antenna size to 19.25 × 10.5 × 1.6 mm3. This miniaturized dual band antenna can be easily integrated into circuit boards. The measured and simulated results provided a reflection coefficient (S11) < –15 dB, which made the antenna suitable for LTE band-40 and 5G mid-band communication applications.
Hybrid Metamaterial for the Secondary Radar Antenna System
Authors: Khamsalee Peerasan , Mesawad Piyaporn , Wongsan Rangsan
Published: August 2020

This paper proposes the gain enhancement of dual-band and dual-polarized asymmetric horn antenna for the secondary radar system using hybrid metamaterial techniques. The hybrid metamaterial is comprised of the structures of woodpile electromagnetic bandgap (EBG) for gain enhancement of the primary main beam of the radar system at the operating frequency of 1,300 MHz with horizontal polarization; and the wire medium structure that is placed beside the EBG structure for gain improvement of the identification friend or foe (IFF) main beam, which is operated at the center frequency of 1,060 MHz with vertical polarization. Meanwhile, the cooperated structures have to function to control the directions of the primary and IFF main beams retaining at 0° and 6°, respectively, too. When the hybrid metamaterial structure is placed at the front of an asymmetric horn’s aperture, with suitable parameters and optimized spacing, it is found to increase the gains of the two beams compared to the single asymmetric horn around 3 dB and retain the directions of original main beams. The comparison of the results between simulation and measurement, such as the reflected power (S11), gain, and radiation patterns, are in good agreement.
Analysis of ‘Flat-Earther’ Posts on Social Media: Reflections for Science Education from the Discursive Perspective of Foucault
Authors: Melo Leonardo Wilezelek Soares de , Passos Marinez Meneghello , Salvi Rosana Figueiredo
Published: August 2020

In this paper we present the results of a research that aimed to analyze posts on a Twitter page of an organization that openly defends that the Earth is flat and to highlight its formative characteristics, as well as to discuss about the possible implications of such defense for Science Education. Discourse analysis was carried out based on the guidelines presented by Foucault and a priori theories were taken from the contributions of Feyerabend, Latour and Stengers. These choices occurred due to the fact that these contributions present heterodox points of view on the production of scientific knowledge, open to implications that are not only epistemological, which makes it possible to discuss the cultural, social and discursive complexity of the ‘flat Earth belief’. It is hoped that the considerations presented here may promote discussions related to the theme on the part of those who work in Science Education and, also, promote reflections on the very ethics of the scientific process and its limits.