bluuebunny/crossref_metadata_2025 huggingface dataset:
Prevalence and antimicrobial resistance of Campylobacter jejuni and Campylobacter coli in slaughtered broiler chickens in Paraguay
Authors: Castro Rojas Liz Aurora , Del Solar-Velarde Jonatan , Weiler Natalie , Orrego Verónica , Sosa-Argaña Diego , Alvarez Fredi
Published: February 2024

Campylobacteriosis is one of the main zoonotic diseases transmitted by food, especially chicken meat and derivatives which represent an important transmission source for humans. This research aimed to verify prevalence and antimicrobial resistance of Campylobacter jejuni and Campylobacter coli in broiler chickens Cobb 500TM obtained from a slaughterhouse in Paraguay. 300 cloacal swabs samples were randomly collected, then subjected to microbiological analysis and subsequent PCR bacterial confirmation. Antimicrobial susceptibility to ciprofloxacin and erythromycin was determined by the E-test®. Campylobacter spp. prevalence was 63.6%, 97.3% corresponding to C. jejuni and 2.6% to C. coli. Resistance to ciprofloxacin was 89.8% for C. jejuni and 100% for C. coli. Resistance to erythromycin was found only in one strain of C. jejuni (0.5%). High resistance to ciprofloxacin and high prevalence of C. jejuni, were confirmed. This research describes public health risk of consumption of chicken meat contaminated with antibiotic-resistant Campylobacter species. The results indicate the need to implement health control measures regarding the antibiotic treatments in poultry production. This research represents the first scientific report that reveals antimicrobial prevalence and resistance of C. jejuni and C. coli in commercial broiler chickens in Paraguay.
Estudio de los cambios químicos en microensilados de exoesqueletos de camarón (Litopeneus vanamei) y chapulín (Sphenarium purpurascens) durante la fermentación en medio sólido
Authors: AMADOR MENDOZA ADOLFO , BRAVO DELGADO HUMBERTO RAFAEL , RAMIREZ SEAÑEZ ANA ROSA , HERNÁNDEZ HERNÁNDEZ HIPÓLITO
Published: February 2024

La fermentación en medio sólido es una técnica utilizada para la producción de quitina, pigmentos, proteínas y lípidos. En el presente trabajo se evaluaron los cambios en la composición química y microbiológica en micro ensilados de exoesqueletos de camarón (Litopeneus vanamei) y chapulín (Sphenarium purpurascens) fermentados con un inoculo comercial de Lactobacillus plantarum AVG-112. Se determinó la cantidad de melaza para la fermentación, la composición proximal y la cuenta microbiológica de los ensilados. Los desechos se mezclaron con melaza de caña de azúcar como fuente de carbono y se inoculó usando una cepa comercial (Lactobacillus plantarum AVG-112). A los 5 días de fermentación ambos ensilados presentaron características físicas y químicas aceptables. Los coliformes totales, mohos y levaduras no estuvieron presentes siendo inhibidos por el proceso de ensilaje. Concluimos que la fermentación en medio sólido tiene características adecuadas para su utilización como suplemento en alimentos para organismos acuáticos.
Aislamiento de bacterias nativas con potencial en la promoción del crecimiento de maíz criollo mexicano (Zea mays L.)
Authors: Sánchez-Ceja Monica Guadalupe , Loeza-Lara Pedro Damián , Carballar-Hernández Santos , Jiménez-Mejía Rafael , MEDINA-ESTRADA RICARDO IVAN
Published: February 2024

El maíz criollo (Zea mays L.) es un alimento emblemático para México, ya que representa un factor importante en cuanto a economía local, cultura y biodiversidad. Las técnicas biotecnológicas donde se emplean bacterias promotoras del crecimiento vegetal (BPCV), son una alternativa sostenible al uso de insumos agrícolas químicos para la producción de maíz, sin embargo, es importante destacar que, lo ideal es utilizar BPCV nativas del suelo y/o cultivo donde se pretendan aplicar, ya que esto asegura la adaptación de las BPCV y garantiza la colonización de la rizosfera, mejorando los rendimientos productivos del cultivo. Por lo cual, el objetivo del presente trabajo, fue aislar bacterias nativas de suelos cultivados con maíz criollo mexicano y demostrar su potencial biotecnológico como BPCV en maíz. Se tomaron muestras de suelo cultivado con maíz criollo mexicano, del municipio de Jiquilpan, Michoacán, México y se lograron obtener 40 asilados, de los cuales 18 presentaron indujeron la germinación de las semillas de maíz en más del 90 %. Además, cuatro aislados mostraron incrementos del 20 al 30 % en la longitud total del brote y aumentos del 25 hasta el 100 % en el peso seco total de las plantas. Los mecanismos asociados a la promoción del crecimiento del maíz fueron los de, solubilización de fosfatos, producción de ácido indol acético y de sideróforos, así como el antagonismo contra hongos fitopatógenos (Penicillium, Rhizopus, Fusarium y Colletotrichum). Por lo cual, concluimos que las BPCV nativas asiladas en el presente estudio, tienen potencial biotecnológico para su uso en maíz criollo mexicano de la región.
Algunas consideraciones acerca del impacto de la violencia social en áreas urbanas con actividad turística
Authors: Alcívar Zambrano Dolores Katherine , Gallardo Dueñas Diana Patricia , Mora Pisco Carmen Inés , Becerra Avila Mauricio Arturo
Published: February 2024

La violencia ha sido un desafío que la humanidad ha enfrentado durante siglos, lo que ha dado lugar a una serie de estudios en busca de descifrar sus causas y proponer soluciones. En términos generales se sabe de la docilidad del vencido y la influencia de los imperios de turno para abrirle espacios a los violentos. A pesar de este panorama, las urbes siguen apostando su crecimiento de cara al futuro, pero si la violencia no se logra controlar será difícil que la aspiración se convierta en alternativa para promover el empleo; sin embargo, queda la opción de la empresa privada, quien con la inversión de capital pudiera aportar en la solución. El objetivo de este trabajo es analizar el impacto de la violencia social en áreas urbanas con actividad turística. Metodológicamente se abordó como una investigación analítica afianzada en la consulta de 34 publicaciones científicas que ponen el foco en el tema estudiado. Se concluye que es urgente cambiar la percepción actual de inseguridad en las ciudades que actúan como destino turístico, de no ser así, se comprometería el progreso y la convivencia social, y prevalecería la acción de quienes hacen el mal sobre los ciudadanos de bien.
Las experiencias interculturales y su influencia en la enseñanza del inglés como lengua extranjera
Authors: Galarza Pucha Jairo Patricio , Estupiñán Lince María Lorena , Guevara Torres Pamela Victoria
Published: February 2024

Esta investigación presenta las experiencias interculturales de los docentes de la Universidad Técnica Estatal de Quevedo y su influencia en la Enseñanza del Inglés como Lengua Extranjera. El objetivo general de este estudio es identificar cómo las experiencias interculturales de los docentes contribuyen en la enseñanza del inglés, determinando y describiendo vivencias interculturales tales como  intercambios académicos, viajes e interacciones con culturas extranjeras a fin de conocer  la manera en que aportan al desarrollo de la competencia intercultural en el aula. Se desarrolló una investigación descriptiva, de carácter mixto, con instrumentos cualitativos y cuantitativos como la entrevista y la encuesta. El análisis de los datos fue temático y de contenido. Se obtuvo que algunos docentes consideran que la experiencia intercultural que poseen les permite realizar actividades donde los alumnos pueden demostrar y aplicar los valores de la cultura extranjera. En cuanto a la competencia intercultural desarrollada en los estudiantes, la mayoría de los participantes hizo énfasis en llevar a los estudiantes a leer y revisar experiencias interculturales, ya sea, a través de los textos o de materiales, recursos y estrategias diversas como videos e interacciones con estudiantes extranjeros mediante videoconferencias. Lo que permite concluir que las experiencias interculturales influyen positivamente en la motivación y el compromiso de los docentes y estudiantes, al crear un ambiente de aprendizaje más estimulante para los estudiantes al oír y aprender de sus experiencias.
Revisiting Punjab’s Transformative Journey: 1947 to 1966
Authors: Bhardwaj Vikram , Sharma Usha
Published: February 2024

Punjab, the “Land of five rivers”, has played a major role in the history of India and had left a deep imprint on the course of Indian History. This imprint on Indian History is due to the people of Punjab, who through their courage and patriotism have carved out an important place for themselves. To understand the nature and dynamics of Punjab history in its true perspective, it is important to study the people of Punjab; their historical, cultural and religious background and their political heritage. In 1947, India got Independence from the British rule and at the same time it was partitioned on the on the basis of two nation theory. In this partition Punjab had to pay a heavy price both in term of human and territorial loss. The joy and achievement of independence for Punjab was marred by the holocaust of partition. After partition Punjab presented a very gloomy and downright dismal picture. Migration of refugees significantly altered the communal composition of Indian Punjab. It also shook the administrative, economic and political machinery of the province to its foundation and brought in its wake a host complicated problems. The division of Punjab on communal lines spread a sense of indignation and frustration among the Sikhs because the hopes of creating a Sikh State in Independent India rose by the Sikh leaders and supported by the congress and Hindu leaders had not been fulfilled. The Sikhs felt that they had been given a raw deal in the distribution of territory between the Hindus and the Muslims giving the expression to this feeling hence the demand for a Punjabi Suba was made and in its struggle for the achievement of Punjabi Suba, the Akali Dal employed a variety of strategies, due to which on 21st March 1966 reorganization of the Punjab took place and Punjab was further trifurcated.
L'Appréhension Juridique, Epistémique et Téléologique du Marché Pertinent en Droits Marocain et Européen de la Concurrence : Etat des Lieux, Enjeux et Réflexion Prospective
Authors: El Azhary Mohamed
Published: February 2024

Une appréhension juridique cohérente des restriction à une concurrence libre et loyale sur le marché présuppose au prime abord l’adoption d’une démarche proactive et systémique qui verrait dans tout «comportement desperado» sur le marché intérieur un outrage à l’égalité des chances entre entreprises. Une restriction ou entrave à l'accès au marché étant considérée une menace déroutante pour le libre jeu de la concurrence ــlequel jeu devant régner en maitre sur « le milieu des entreprises » acteurs principaux du marché intérieurــ et à ce titre un obstacle à aboulir. Néanmoins, une approche proactive et systémique, de nature à contribuer à la préservation de l’égalité dans la concurrence voire à l’exhortation du dynamisme de compétition entre les protagonistes présents sur le marché, demeure tributaire de l’intérêt porté à l’acte de «la définition du marché pertinent» lui-même. Dès lors, la présente étude s'inscrit dans une perspective de recherche visant à tracer les rebords afférents au rôle joué par l’acte de «la définition du marché pertinent» dans le dessein de la mise en exergue du droit de la concurrence. Cette étude vise pareillement à démystifier les tournures épistémologiques qu’il faudrait déployer à l'échelle des autorités de la concurrence des systèmes juridiques sous examen pour concrétiser tous les objectifs du pacte légal de stabilité des entreprises sur le marché intérieur. The mission of apprehension of obstacles to market access presupposes above all the adoption of an approach which would see in any « desperado behavior » on the internal market an outrage on equal opportunities between companies. A restriction on the free play of competition which should reign supreme over « the business environment ». This approach - which is likely to contribute to the preservation of equality in competition or even to the encouragement of competitive dynamism between the protagonists present on the market - remains dependent on the interest shown in the act of « the definition of the relevant market » itself. Therefore, the purpose of this study is to trace the edges relating to the role played by the act of «defining the relevant market» in the aim of highlighting competition law. This study also aims to demystify the epistemological aspects that should be deployed at the level of competition authorities to achieve all the objectives of the legal pact for the stability of companies on the market.
Etude Analgésique des Extraits hydroéthanolique de Clerodendrum splendens et Nephrolepis bisserata : Deux Plantes de la Pharmacopée Ivoirienne
Authors: Tidou Sylvie Noëlle , Kouakou Landry Sylvain , Kouakou Gisèle Siransy , Zirihi Guédé Noëlle
Published: February 2024

La présente étude a pour objectif général d’évaluer l’activité analgésique des extraits hydroéthanolique de Clerodendrum splendens et Nephrolepsis bisserata. Cette évaluation s’est faite en utilisant le Writhing test induit par l’acide acétique 1% par voie intrapéritonéale et le test d’immersion de la queue chez a souris. Le paracétamol, à la dose 100 mg/Kg de poids corps corporelle (pc) et l’extrait hydroéthanolique ont été administrés par voie orale. La morphine à la dose de 10 mg/kg de pc a tété administrée par voie intrapéritonéale. Les résultats ont montré que les extraits de Clerodendrum splendens et Nephrolepsis bisserata administrés aux doses de 50, 100 et 200 mg/Kg de pc chacun présentaient des pourcentages d’inhibition respectivement de 56,44 ; 61,28 ; 98,39, 98,39, 87,10 ; 95,16 contre 91, 93 pour le paracétamol. Aux temps T30, la morphine a fortement prolongé le retrait de la queue des souris avec une moyenne de 8,6±0,2 s contre 3,6±0,2 s, 4,4±0,5 s et 5,6±0,2 s pour notre solution de (NB+CS) respectivement aux doses de 5mg/ml, 10mg/ml et 15mg/ml. Cependant à la 150éme minute, notre extrait a fortement prolongé les temps de retrait de la queue des souris avec des moyennes de 8±0,4, 10,6±0,5 et 12,2±0,4 s (respectivement aux doses de 5mg/ml, 10mg/ml et 15mg/ml) par rapport à celui de la morphine (6,2±0,2 s). L’effet analgésique de Clerodendrum splendens et Nephrolepsis bisserata justifierait leur utilisation par les populations pour soulager la douleur. The general aim of the present study was to evaluate the analgesic activity of hydroethanol extracts of Clerodendrum splendens and Nephrolepsis bisserata. This evaluation was carried out using the Writhing test induced by 1% acetic acid intraperitoneally and the tail immersion test in mice. Paracetamol at a dose of 100 mg/Kg body weight (bw) and hydroethanol extract were administered orally. Morphine at a dose of 10 mg/kg bw was administered intraperitoneally. The results showed that extracts of Clerodendrum splendens and Nephrolepsis bisserata administered at doses of 50, 100 and 200 mg/Kg bw each presented inhibition percentages of 56.44; 61.28; 98.39, 98.39, 87.10; 95.16 respectively versus 91, 93 for paracetamol. At times T30, morphine greatly prolonged tail withdrawal in mice, with an average of 8.6±0.2 s versus 3.6±0.2 s, 4.4±0.5 s and 5.6±0.2 s for our (NB+CS) solution at doses of 5mg/ml, 10mg/ml and 15mg/ml respectively. However, at the 150th minute, our extract greatly prolonged the tail withdrawal times of the mice, with averages of 8±0.4, 10.6±0.5 and 12.2±0.4 s (at doses of 5mg/ml, 10mg/ml and 15mg/ml respectively) compared with morphine (6.2±0.2 s). The analgesic effect of Clerodendrum splendens and Nephrolepsis bisserata justifies their use by local populations to relieve pain.
Advances in understanding the nutritional and nutraceutical properties of apples
Authors:   “Dunărea de Jos” University of Galați, Romania, Ploscuțanu Gabriela
Published: February 2024

This chapter reviews the latest scientific studies on the health benefits of apples, including fresh, canned, frozen, dried and/or juice (clear and cloudy) and their phytochemicals. Due to their popularity, accessibility and high nutritional content, apples have been the subject of many scientific studies targeting chronic disease prevention. Their consumption has been correlated with positive outcomes for a variety of diseases, including cancer, diabetes, osteoporosis, cardiovascular disease, cognitive and lung disorders.
Advances in understanding the development of antioxidant nutraceutical compounds in apples
Authors:   Free University of Bolzano, Italy, Scampicchio Matteo
Published: February 2024

This chapter provides an overview of the antioxidant nutraceutical compounds found in apples. Apples have always been recognised as foods with high nutritional value. In addition, their health benefits have always been the subject of intense research. This chapter summarises the characteristics and properties of the antioxidant compounds found in apples, their bioavailability, and the mechanisms by which they exert their antioxidant effects. The effects of maturation, ripening, and post-harvesting on the resulting antioxidant content are also discussed.
Geografía de la desigualdad de género en México
Authors: Díaz Barajas Yesica , Zamora Torres América Ivonne
Published: February 2024

La desigualdad de género en México es aún un obstáculo para que la población femenina alcance su máximo potencial humano, en concordancia con los avances en el desarrollo de las regiones, por lo que los estudios que abonan a cuantificarla, representan importantes herramientas de análisis para incorporar y priorizar en la agenda pública diferentes temas de género. En el documento, se aborda el contexto teórico y referencial de algunas aristas de la desigualdad de género, priorizando las dimensiones de salud reproductiva, empoderamiento y trabajo. Este trabajo tiene por objetivo identificar la estructura geográfica de la desigualdad en nuestro país, mediante un análisis de clústeres k-medias, partiendo del Índice de Desigualdad de Género Ampliado (IDGA) calculado previamente para las entidades federativas de México en 2020, lo cual permite encontrar las convergencias y divergencias en desigualdad de género en las tres dimensiones que contempla el índice, agrupando las entidades de acuerdo con su similitud en el grado de avance hacia la igualdad: líderes, seguidoras y rezagadas. En los resultados se destaca que, en el avance general hacia la igualdad de género, cinco entidades componen el clúster de líderes, con valores del IDGA menores a 0.337; quince entidades pertenecen al clúster de seguidoras, con índices entre 0.386 y 0.430; y doce entidades conforman el clúster de rezagadas, con valores superiores a 0.431, siendo Chiapas el estado con mayor desigualdad de género, rezagado en las tres dimensiones.
Burfoot, Annette & Güngör, Derya (2022). Women and Reproductive Technologies. The Socio-Economic Development of Technologies Changing the World
Authors: Otín-Gavín Jorge
Published: February 2024

Este artículo reseña:  Burfoot, Annette & Güngör, Derya (2022). Women and Reproductive Technologies. The Socio-Economic Development of Technologies Changing the World. New York, NY: Routledge.
FACTORS ASSOCIATED WITH THE OCCURRENCE OF PRIMARY MULTIDRUG-RESISTANT TUBERCULOSIS IN MEDAN
Authors: Hutomo Rizky Aditya , Wahyuni Chatarina Umbul , Sarumpaet Sorimuda
Published: February 2024

Background: Tuberculosis (TB) treatment failure may lead to multidrug-resistant tuberculosis (MDR-TB). This failure can be detrimental to patients, not only causing death, but can also be transmitted to others, and those who are infected directly fall into the category of MDR-TB so that it can be referred to as primary MDR-TB. MDR-TB is the biggest problem in the prevention and eradication of TB worldwide. MDR-TB is a type of Mycobacterium tuberculosis resistance to at least the first two TB drugs of choice, including Isoniazid and Rifampicin. Purpose: This study aimed to determine the association between education, contact history, and knowledge regarding the occurrence of primary MDR-TB. Methods: This study used a cross-sectional study conducted at Community Health Center in Medan from November 2021 to February 2022. A total of 47 TB patients were selected for this study through purposive sampling methods. The dependent variable was primary MDR-TB occurrence while the independent variables consisted of several characteristics, namely education, contact history, and knowledge. The data were analyzed using chi-square. Results: in this study, sex  (p=0.56; PR=1.12; 95% CI= 0.30<1,12<4,14;) and education (p=0.40; PR=0.56; 95% CI= 0.14<0.56<2.19) was not associated, while age (p=0.02; PR=0.16; 95% CI=0.02<0.16<0.94), contact history (p<0.001; PR=7.94; 95% CI=2.11<7.94<29.83) and poor knowledge (p=0.01; PR=5.00; 95% CI= 1.31<5.00<18.96) were associated with an occurrence of primary MDR-TB. Conclusion: the prevalence of primary MDR-TB increases with age, contact history, and poor knowledge.
PREVALENCE OF MENSTRUAL MIGRAINE AND THE EFFICACY OF SUMATRIPTAN ADMINISTRATION
Authors: Maridsky Aldilla Afifie Putri , Sudibyo Devi Ariani , Qurnianingsih Ema , Dyah Kencono Wungu Citrawati
Published: February 2024

Background: Menstrual migraine is a primary headache that often attacks women of reproductive age. This type of migraine has high severity and is resistant to treatment. Therefore, an effective treatment is needed to treat this menstrual migraine. Sumatriptan has been shown to have a better effect as an acute treatment for menstrual migraine patients. Purpose: This study aims to determine the prevalence and effectiveness of sumatriptan as a therapy for menstrual migraine. Methods: This research is based on a literature review following predetermined inclusion criteria. First, a literature search was carried out adhering to the PRISMA flow in 4 databases: Pubmed, Science Direct, ProQuest, and ClinicalTrial.co. Results: Based on keywords, 267 studies were found in the literature search. However, only three studies covering 845 participants met the predetermined inclusion criteria. The average age of menstrual migraine patients in the three studies was 37 years. These three studies of sumatriptan revealed a significant effect in providing a pain-free response in menstrual migraine patients. These three studies also showed that sumatriptan 100 mg has a higher level of effectiveness in providing a pain-free response in menstrual migraine sufferers and was preferably given during mild attacks. Conclusion: These three studies indicate that typically, women who suffer from menstrual migraines are of reproductive age. Additionally, this study shows that using sumatriptan as an acute therapy significantly helps provide a pain-free response in menstrual migraine patients.
TUBERCULOSIS SURVEILLANCE SYSTEM EVALUATION IN BLITAR DISTRICT: STUDY OF SYSTEM APPROACH AND ATTRIBUTES
Authors: Florentji Adel Benu Friwanti , Atoillah Isfandiari Muhammad , Pramono Endro
Published: February 2024

Background: Blitar district was in the last second position in East Java Province, achieving low Tuberculosis recovery and treatment of the national target by 2022. Therefore, it is necessary to support surveillance systems as a prerequisite for providing information as decision-making material. Purpose: to describe the quality of the tuberculosis surveillance system based on its approach and attributes. Methods: This research was an evaluation study design on the tuberculosis surveillance system in 2022. Respondents totaled 19 people. Data was collected by interview using a questionnaire and document study using a checklist. Data was analyzed by comparing the system approach and surveillance attributes to existing guidelines. The data was presented in tables and narratives. Results: Evaluation of tuberculosis surveillance systems based on input, process, and output was available by surveillance guidelines. Evaluation of the surveillance attributes showed that the flexible system has high data quality, high sensitivity, timeliness, and high stability. However, the system is not simple in operation, has low acceptability of the network, and has low positive predictive value because the suspect detection is too loose and not representative. Conclusion: The implementation of the tuberculosis surveillance system has largely been carried out well, supported by several complete surveillance attributes. It is necessary to provide standard operational procedures for recording and reporting, improve coordination with the network to manually and electronically report suspected tuberculosis, and optimize the Mantoux test in children.
SUSTAINABLE APPROACH TOWARDS URBAN RIVERFRONT DEVELOPMENT : A CASE STUDY OF MULA-MUTHA RIVER, PUNE, MAHARASHTRA
Authors: Kumbhre A V , Barman J , Bharule S
Published: February 2024

Rivers play a vital role in enhancing the identity of any city. Similarly, Mula, Mutha, and Mula-Mutha rivers are the identity of Pune city. When we look at the rivers of Pune closely, we will find the horrendous scenario. The major issues with the rivers of Pune are river flooding, river pollution, partial dry riverbeds, underutilized riverbanks, slum encroachment, and inaccessibility. These rivers are in a vulnerable state due to rapid urban growth. The unplanned growth of Pune city has degraded the quality of its river. The overall perspective towards the river has changed and the city is showing its back to its rivers. These kinds of scenarios have raised challenges for Pune city which is affecting the lives of its citizens. Therefore, we should investigate these issues closely and come up with the best possible compatible solutions for retaining the identity of the city and enhancing the quality of life. The riverfront development along these rivers can overcome these issues and integrates socio-cultural, economic, and environmental activities which are existing along the rivers of Pune.
RIVER WATER QUALITY MODELING BASED ON DO AND BOD PARAMATERS USING QUAL2KW SOFTWARE (CASE STUDY : WINONGO RIVER, SPECIAL REGION OF YOGYAKARTA)
Authors: Rahmi R , Marlina N , Rahmawati S
Published: February 2024

The location of the study was on the 46.93 km Winongo River which passes through the Sleman Regency, Yogyakarta City, and ends in Bantul Regency. The Winongo River receives sources of pollutants such as domestic waste, agricultural waste, and fishery waste so river pollution occurs. The purpose of this study is to analyze the water quality of the Winongo River with point source and nonpoint source pollutant sources and obtain alternative strategies for Winongo river water quality management from the results of Qual2kw modeling simulations that can increase DO concentration and reduce BOD concentration. Based on the results of the study showed that the occurrence of pollution in the Winongo River, as evidenced by the average BOD concentration that exceeded the class II quality standard of 4.45 mg / L and the concentration of 5.38 mg / L. Simulation results of pollutant load modification and local oxygenation simulations were effective in increasing DO concentrations in the Winongo River. Meanwhile, the simulation of local oxygenation and simulation of modification of pollutant loads are effective in reducing BOD concentrations in the Winongo River.
THE CONDITION OF THE SETIAMANAH LAKE IN TERMS OF WATER QUALITY
Authors: Wardhani E , Fitriani N A
Published: February 2024

Setiamanah Lake is located in Setiamanah Village, Central Cimahi District, Cimahi City. This lake has an area of 0.04 ha with a depth of 5 m and a volume of 1.204.5 m3. This lake functions as a rainwater shelter and is planned to be used as a raw water source. This lake is part of the Cisangkan River watershed. The activities of residents in the watershed significantly affect the lake’s water quality. Activities in the Cisangkan River Basin consist of domestic, non-domestic, agricultural, and plantation activities. The Setiamanah lake will be designated as a source of raw water, so it is necessary to analyze the water quality and determine its quality status to find out how the water conditions and the lake management are. Water quality analysis was carried out in October 2021 (rainy season) and April 2022 (dry season) with 23 parameters analyzed. In 2021 12 parameters do not meet the standards, and in 2022 9 parameters do not meet the quality standards. The quality standard used is Government Regulation No.22 of 2021 class I. Based on the calculation of water quality status using the pollutant index method, Setiamanah Lake in both seasons shows mild contamination, with the pollutant index value in 2021 being 8.398 and in 2022 being 8.325.
REVIEW OF RESEARCH METHODS IN CONCESSION PERIOD FOR PUBLIC PRIVATE PARTNERSHIP
Authors: Suryaningrum A , Utomo C , Santoso E
Published: February 2024

Public Private Partnership (PPP) needs to be developed, related to the construction of infrastructure projects that require large costs incurred by the government. One of the important variables in preparing PPP contracts is to determine the concession period by taking into account the risks and uncertainties that occur during the concession period. The purpose of the study is to find out the research methods used related to the concession period by analyzing 30 papers related to the concession period. In the collection of research data, there are quantitative and qualitative approaches. The methods used in each study use different methods, based on the analysis of research methods from 30 papers. In the topic of discussion of the concession period, in general, the paper discusses the type of modeling, decision criteria, solutions, cases, research objects, risks and uncertainties and methods used. Previous studies related to the concession period have many different methods and objectives, In quadrant mapping shows that the use of quantitative methods with secondary data is the most dominant. Based on the reviews that have been carried out in this study, it can be concluded that the use of quantitative methods with secondary data is the most dominant.
CONCEPTUAL IDEA OF DESIGN AUTOMATION FOR BUILDING ENERGY
Authors: Utomo C , Rahmawati Y , Aqsha A
Published: February 2024

Connected construction is open communication between technologies. It is the most advanced form of technology today in the field of construction. Currently, modeling technology has been developed to help in understanding the design and building management strategies and decisions. Although it has been very advanced, it still has weaknesses in the shared system, as well as in building system products and stakeholders. Automation technology creates reliable control in connected construction processes that drive cost-efficiency. It process integrates building design, construction, and operations and also integrates developers, construction players, and building system manufacturing industries. This paper aims to present a concept of an automated support system that allows automated design decisions and management as a control of the connected construction. A Multi-Agent System (MAS) is applied to provide an appropriate decentralized approach to the characteristics of fragmentation in construction. As the result, the method covers 19 functionalities. The solution is more optimal and gives efficiency and effectiveness to deal with changing circumstances and problem-solving where data, expertise, and control are distributed.
UTILIZING FOREST CITY AS A FORM OF THERAPY TO CREATE A WORLD CITY FOR ALL IN INDONESIA’S NEW CAPITAL
Authors: Prabowo H , Dewi M P , Dewi D S E , Hartatik Hartatik , Firdaus M F , Afandi N A , Ismayenti L
Published: February 2024

A literature review that proposes forest therapy is presented in this study. The Indonesian government is creating a forest city as its new capital city, in which this therapy is being explored. If integrated into the forest city in the new capital city, forest therapy offers a variety of physical and psychological health benefits. It is anticipated that the forest city would not only improve the health of the capital’s residents but will also bring about the realization of a world city for all.
SORIK MARAPI POWER PLANT DISASTER PREPAREDNESS LEVEL
Authors: Negara A R P , Sarwidi S , Nugraheni F
Published: February 2024

Sorik Marapi Geothermal Power (SMGP) is one of the largest developing geothermal projects in Indonesia. This project is located in Mandailing Natal Regency, North Sumatera Province. KS ORKA acquired the majority shares of the company in mid-2016 and since then the project has completed drilling program for 18 wells and confirmed at least 55 MW of proven resources. The project aims to connect 240 MW power to The PT PLN grid. The Steam field Diagram Options (SAGS) conceptual design based on the wellpad separation concept with the separated fluids running the Well Head Units (WHU) installed within the production well pad. This SAGS concept is a decentralized system with shorter pipelines per plant. The SAGS concept has the advantage of a faster time to see its development compared to the traditional concept. High risk of that could occurs during geothermal exploration and development activities identifying risks of geohazard in early phase of geothermal development plan might cause some problems and catastrophic events such as damages on infrastructure, well pad, road access, pipeline, well leaks or broken, impairment of power plant facilities, and following cessation of electricity production. Moreover, these events also could affect the nature or environment surrounding the field and results fatality or loss of human lives. Therefore, it is very critical to have a well – structured and comprehensive method as a guide to identify and mitigate the geohazard risks. The aim of this study is to gathers and reviews disaster preparedness level in SMGP Project area especially geohazard such as earthquake and landslide. Evaluation of existing building using FEMA P-154 and ASCE 41-17 Tier 1 and 2 also explained on this study.
Treatment Strategies for Anti-vegf Resistance in Neovascular Age-Related Macular Degeneration by Targeting Arteriolar Choroidal Neovascularization
Authors: Fu Yingbin , Zhang Zhao , Webster Keith , Paulus Yannis
Published: February 2024

Despite extensive use of intravitreal anti-vascular endothelial growth factor (anti-VEGF) biologics for over a decade, neovascular age-related macular degeneration (nAMD) or choroidal neovascularization (CNV) continues to be a major cause of irreversible vision loss in developed countries. Many nAMD patients demonstrate persistent disease activity or experience declined responses over time despite anti-VEGF treatment. The underlying mechanisms of anti-VEGF resistance are poorly understood, and no effective treatment strategies are available to date. Here we review evidence from animal models and clinical studies that supports the roles of neovascular remodeling and arteriolar CNV formation in anti-VEGF resistance. Cholesterol dysregulation, inflammation, and ensuing macrophage activation are critically involved in arteriolar CNV formation and anti-VEGF resistance. Combination therapy by neutralizing VEGF and enhancing cholesterol removal from macrophages is a promising strategy to combat anti-VEGF resistance in CNV.
Solid Waste Management Practice and Landfill Suitability the Case of Sendafa Town, Ethiopia
Authors: Bedane Sintayehu Legesse
Published: February 2024

The purpose of this study is to assess the solid waste management status and practice in Sendafa town, Oromia regional state residents. In order to achieve this goal, the researcher intends to employ both primary and secondary data from the Sendafa town municipality. With the aid of multi-cluster sampling and a purposive sampling method, the researchers chose a sample size of 398 people and 10 interview responders. To utilize a systematic sampling technique at intervals of residences, individual samples were chosen. Quantitative data was cleaned and analysed using STATA software. A multiple linear regression model and logistic regression other descriptive statistics methods were then used to change the results. The qualitative data were imported, coded, and thematised using ATLAS.ti.9 in order to prepare respondents' interviews for analysis. The findings indicate that residents' poor solid waste management practices are a result of a lack of awareness, low family income transportation issues, issues with waste collectors, a lack of a sense of responsibility and belonging, and a failure to enforce current solid waste management laws. Solid waste accumulates near roads, bridges, and residential areas that are close to landfills, contaminating the area and leading to diseases like TB and Asthma (and other related health issues in children and adults who live there). Thus, researcher recommends that to have sustainable solid waste management the town administrators should have plan to develop awareness creation symposium or panel of discussion, resolve transportation issues, monitor and guide the routine activities of waste collectors, develop sense of belongingness for themselves and for the community, develop integrated solid waste land fill projects and working with all stakeholders like NGO and health institution will minimize the adverse effect of improper solid waste management.

Keywords: Solid Waste, Status of Solid Waste Management, Land fill site suitability
Experimental Linear and Nonlinear Vibration Methods for the Structural Health Monitoring (SHM) of Polymer-Matrix Composites (PMC): A Literature Review
Authors: Dolbachian L. , Harizi W. , Aboura Z.
Published: February 2024

The goal of this article is to provide a review of the experimental techniques and procedures using vibration methods for the Structural Health Monitoring (SHM) of Polymer-Matrix Composites (PMC). It aims to be a guide for any researchers to carry out vibration experiments. The linear methods are first introduced. But as PMC is a complex material, these classic methods showed some limits, such as low accuracy for small damages, and a high environmental dependency. This is why the nonlinear methods are secondly studied, considering that the complexity of PMC induces a nonlinear behavior of the structure after damage occurrence. The different damage mechanisms are well explained in order to evaluate the potential of each vibration method to detect them.
Investigating the Potential Double-Edged Score of Immigration-Related Stress, Discrimination and Mental Health Access
Authors: Andrews Arthur R , Escobar Kevin , Estrada Gonzalez Sandra Mariely , Reyes Sara , Acosta Laura M
Published: February 2024

Prior work has suggested that discrimination and immigration-related stress may impede mental health care seeking and utilization among Latinx populations. These effects may be more nuanced as both discrimination and immigration-related stress may increase symptomology, particularly posttraumatic stress disorder (PTSD) and depression. Both symptoms may in turn prompt attempts to seek care. The current study examined the direct effects of discrimination and immigration-related stress on care access, as well as potentially indirect effects with PTSD and depression symptoms as mediators. Interviews and online surveys were completed with 234 Latinx residents of the Midwest assessing everyday discrimination, discrimination in healthcare, PTSD symptoms, depression symptoms, current mental health utilization, and previous unsuccessful attempts to seek care. Direct effects of discrimination and immigration-related stress were largely unrelated to care access variables. Discrimination in healthcare settings predicted both unsuccessful attempts to seek care and current use, but this effect was positive. The indirect effect was largely supported, but only for PTSD symptoms and not depression. Results indicate further investigation is necessary to understand the direct effects of discrimination on care access. Further, discrimination and immigration-related stress may indirectly prompt attempts to seek mental health care.
Gut Microbiota Signatures with Potential Clinical Usefulness in Colorectal and Non-small Cell Lung Cancers
Authors: Tesolato Sofía , Vicente-Valor Juan , Paz-Cabezas Mateo , Gómez-Garre Dulcenombre , Sánchez-González Silvia , Ortega-Hernández Adriana , De la Serna Sofía Cristina , Domínguez-Serrano Inmaculada , Dziakova Jana , Rivera-Alonso Daniel , Jarabo-Sarceda José Ramón , Hernando Trancho Florentino , Martinez Ana maria gomez , Torres-García Antonio José , Iniesta Pilar
Published: February 2024

The application of bacterial metagenomic analysis as biomarker for cancer detection is emerging. Our aim was to discover gut microbiota signatures with potential utility in the diagnosis of colorectal cancer (CRC) and non-small cell lung cancer (NSCLC). A prospective study was performed on a total of 77 fecal samples from CRC and NSCLC patients and Controls. DNA from stool was analyzed for bacterial genomic sequencing using the Ion Torrent™ technology. Bioinformatic analysis was performed with QIIME2 pipeline. We applied logistic regression for adjusting differences attributable to sex, age and body mass index and compared diagnostic accuracy of our gut signatures with other previously published.
The feces of patients affected by different tumor types, such as CRC and NSCLC, showed a differential intestinal microbiota profile. After adjusting for confounders, Parvimonas (OR = 53.3), Gemella (OR = 6.01), Eisenbergiella (OR = 5.35), Peptostreptococcus (OR = 9.42), Lactobacillus (OR = 6.72), Salmonella (OR = 5.44) and Fusobacterium (OR = 78.9) remained significantly associated with the risk of CRC. Two genera from the Ruminoccocaeae family, DTU089 (OR = 20.1) and an uncharacterized genus (OR = 160.1) were associated with the risk of NSCLC. Our two panels had better diagnostic capacity for CRC (AUC = 0.840) and NSLC (AUC = 0.747) compared to the application to our population of two other published panels.
Thus, we propose a gut bacteria panel for each cancer type and show its potential application in cancer diagnosis.
First Report of the Emerging Pathogen Kodamaea ohmeri in Honduras
Authors: Ortiz Bryan , López Roque , Muñóz Carlos , Aguilar Kateryn , Pérez Fernando , Laínez-Arteaga Isis , Chávez Fernando , Galindo Celeste , Rivera Luis , Ballesteros-Monrreal Manuel G , Mendez-Pfeiffer Pablo , Valencia Dora , Fontecha Gustavo
Published: February 2024

Kodamaea ohmeri is an environmental yeast considered a rare emerging pathogen. In clinical settings, the correct identification of this yeast is relevant since some isolates are associated with resistance to antifungals. There is a lack of available data regarding the geographical distribution, virulence, and drug resistance profile of K. ohmeri. To contribute to the knowledge of this yeast, this study aimed to describe in depth three isolates of K. ohmeri associated with fungemia in Honduras. The identification of the isolates was carried out by sequencing the ribosomal ITS region. In addition, the sensitivity profile to antifungals was determined, and some properties associated with virulence were evaluated (exoenzyme production, biofilm formation, cell adhesion, and invasion). The isolates showed strong protease, phospholipase, and hemolysin activity, in addition to being biofilm producers. Adherence and invasion capacity were evident in the HeLa and Raw 264.7 cell lines respectively. This study expands the understanding of the underlying biological traits associated with virulence in K. ohmeri and is the first report of the detection and identification of K. ohmeri in Honduras as a cause of human infection.
Brain-Based Formulation of Cognitive Behavioral Therapy: A Compass of Therapists across the Brain Ocean
Authors: Yokoyama Satoshi
Published: February 2024

Although there is a vast body of neuroscientific research on cognitive behavioral therapy (CBT), many therapists are confused about how to incorporate the evidence into their clinical practice. This narrative review translates neuroscientific research on CBT for depression into a therapist-friendly formulation model. Four brain networks that are particularly relevant to depression, including the Central Executive Network, Default mode Network, Salience Network, and Affective Network, were identified based on their interactions and described in relation to depressive symptoms. Additionally, it clarified how each CBT technique works on a brain map. Assessment, intervention selection, and patient psychoeducation based on this model will facilitate the clinical application of neuroscience in CBT.
Strategy Development Based on the Hydrogen Businesses in Côte d’Ivoire
Authors: Angbé Kassé Jean Hugues , Nougbléga Yawovi , Narra Satyanarayana , Singh Vidhi
Published: February 2024

Côte d’Ivoire has substantially neglected crop residues from farms in rural areas. This study aims to provide strategies for the sustainable conversion of crop residues to hydrogen. Using existing data and theoretical approaches, up to 16,801,306 tons of crop residues of 11 crop types were available in Côte d’Ivoire in 2019. A theoretical hydrogen potential of 1,296,424.84 tons was estimated from the crop residues. Technically, 907,497.39 tons of hydrogen is expected annually. Three scenarios of hydrogen project implementation developed indicated that the Ivorian industries can be supplied with 9,026,635 gigajoules of heat. Moreover, 17,910 cars and 4,732 buses can be supported in the transport sector. It is estimated that 817,293.95 tons of green ammonia for farmers can be supplied. Five million, seven hundred twenty-seven thousand, nine hundred ninety-two (5,727,992) households are expected to have access to 1,718.40 gigawatts of electricity. Due to these changes in transport, energy, industry, and agricultural sectors, a reduction of 1,644,722.08 tons of carbon dioxide per year can be achieved theoretically. With the scenarios, some 263,276.87 tons of hydrogen are exportable to other countries. Conversion of crop residues to hydrogen is a promising opportunity with environmental and socio-economic impact. Therefore, this study requires further extensive research.
The Port Sector in Italy: Its “Keystones” for an Energy-Effective Growth
Authors: Nigro Marialisa , De Domenico Massimo , Murgia Tiziana , Stimilli Arianna
Published: February 2024

Italy has been defined as the "logistics platform" of the Mediterranean Sea. The Italian port system, with 11,6 million TEUs handled and 61,4 million passengers by 2022 (Assoporti data Jan‐Dec 2022) [1] is the key to guarantee this condition through adequate levels of reliability, safety and sustainability. This contribution addresses port logistics and shipping, focusing on primary issues related to the energy sector with a specific focus on what can be observed in the Italian context. Specifically, decarbonization of the maritime sector and related infrastructural problems (e.g. Cold Ironing or alternative fuels, where the uncertainty about resources availability and related cost do not allow for an easy strategic planning by both the shipowner and the port authority), as well as policies such the Emission Trading System (ETS) will be analyzed. All these issues, if addressed with a critical review, could represent the driving force of the national port sector for its growth and its competitiveness at a global scale.