bluuebunny/crossref_metadata_2025 huggingface dataset:
Assessing the overall relative satisfaction index of students towards college facilities: a cross-sectional study
Authors: Doddaiah Sunil Kumar , Anil Deepak , Vijaylakshmi Vadaga Rao , Gopi Arun , Murthy Mysore Ramakarishnaiah Narayana
Published: March 2022

Background: A sound social environment is a key determinant to a students’ welfare and improved academic performance.Methods: An online cross-sectional study was undertaken among 172 medical students residing in the hostel facility of a medical college in urban Mysuru. A pre-tested RSI questionnaire was administered to the students to assess their overall satisfaction with the hostel facilities and the campus.Results: Out of the 172 study participants who filled the questionnaire, the majority of them were females (56.98%). 70 (40.69%) students belonged to the second year, 31 (18.04%) were from the first year while 24 (13.95%) participants were in internships.Conclusions: The study showed that students had moderate satisfaction with the hostel facilities and the campus. However, both the boys and girls were dissatisfied with the hostel canteen’s hygiene and facility.
Challenges encountered among community-delivered malaria volunteers in Greater Mekong Sub-region for malaria elimination: a systematic review
Authors: Shwe Nanda L. , Hlaing Thein , Tun Kyaw M.
Published: March 2022

In the Greater Mekong Sub-region (GMS) countries, community-delivered malaria volunteers (CDMVs) have been serving a vital role in providing primary preventive and curative services of malaria in the uncovered areas, but they have encountered different challenges. The main purpose of this systematic review was to determine the CDMVs’ challenges in malaria elimination settings of the GMS. A review team applied MEDLINE and PubMed, Google Scholar, and Myanmar Health Sciences Research Journal as major databases and Boolean operators as the focus search for selecting a final set of 46 English studies designed with qualitative and quantitative, and published in 2010 and after. The service qualities of CDMVs were affected by different challenges: motivational challenges (lack of incentive pay, supervision, shortage of malaria supply and inadequate training), community acceptance challenges (negative comments and less preference of community, unawareness of the CDMVs' roles, and inappropriate care of traditional healers), technical challenges (unsatisfactory knowledge and practices, complexities of reporting formats and applications), communication and transportation challenges (lack of electricity and Internet, inapplicability of transportation aids and poor road infrastructure), safety challenges (testing blood with unsafe technique), financial and logistic supply challenges (lack of supply for additional costs, and interruption of malaria ‘supply’) challenges in malaria management (difficulties in managing the patients with mixed malaria, invalid RDT results and severe patients). This review recommends that more research on the community malaria services should be invited and the malaria programmers from each GMS country should establish more perfect volunteer policies for eliminating the CDMVs’ challenges.
A 3 years retrospective observational study of pure tone audiometry in a tertiary railway hospital
Authors: Puthukudy Preetham A. , Feshan Musarrat , Karuthedath Sowmya
Published: March 2022

Background: Pure tone audiometry (PTA) is the basic test to identify the type and severity of a hearing loss.

Methods: Retrospective “record-based” analysis was done on the PTA reports over 03 years from May 2018 to April 2021 and 1420 PTA were analyzed. The tests were done using Arphi digital audiometer 2001 and Proton Dx-5 audiometers.  

Results: 905 (63.73%) were males and 515 (36.27%) were females. Till 50 years of age, mixed hearing loss (MHL) was the commonest type of hearing loss followed by sensorineural hearing loss (SNHL). Overall SNHL was the most common type of hearing loss followed by MHL, while conductive hearing loss (CHL) was the least common. Moderate hearing loss was the most common finding seen in 27.6% of patients in the right ear and in 25.1% of the left ears. This was followed by mild, moderately severe, severe and profound hearing loss in both the ears. The age group with the maximum number of patients was in the 7th decade with 444 (31.27%). The prevalence of presbycusis was 70.60% above 60 years of age.

Conclusions: PTA is a basic investigation to detect the type and severity of hearing loss. The prevalence of hearing loss increases with age and early detection is advisable for early rehabilitation which can delay the onset of dementia.
Pediatric thyroid abscess: an unusual late complication of COVID-19 infection
Authors: Maithani Tripti , Gupta Mudit , Dogra Rishabh , Hernot Sharad
Published: March 2022

Coronavirus disease 2019 (COVID-19) infection in children usually presents as mild infection. There have been several reported papers of thyroid dysfunction in adults suffering from SARS-CoV-2 infection but there hasn’t been any reported case in pediatric population. We report first pediatric case of post COVID-19 thyroid abscess that developed 6 weeks post infection.
Sphenoid sinus mucocele: a review
Authors: Swain Santosh Kumar
Published: March 2022

Sphenoid sinus mucocele (SSM) is a benign, encapsulated, expansile, locally destructive mass within the sphenoid sinus, filled with mucous and lined by epithelium. The exact etiology of the sphenoid sinus mucocele is still not known. The proximity of the SSM to the orbit and brain may cause morbidity and potential mortality if left without intervention. SSM has varied clinical manifestations. Headache and visual disturbances are common symptoms. Diagnostic nasal endoscopy and computed tomography (CT) scan and/or magnetic resonance imaging (MRI) are important pre-operative investigations. Diagnosis of SSM is done by computed tomography (CT) scan of the nose and paranasal sinus which shows a hypodense cystic lesion in the sphenoid sinus. MRI is helpful to detect the extension of the mucocele to orbit and cranium. Treatment of SSM is surgical which include endoscopic transnasal sphenoidotomy with sufficient removal of anterior and inferior walls of the sphenoid sinus for allowing adequate drainage and to avoid recurrence. The endoscopic approach is a safe and effective method of treatment for SSM with fewer recurrences than an open approach. Marsupialization of the mucocele via transnasal transsphenoidal approach is another option with a good outcome. The literature review for sphenoid sinus mucocele was performed from the database of Pub Med, Medline, Scopus, and Google scholar search with the term sphenoid sinus mucocele. Here, this review article is attempting to discuss the details of the sphenoid sinus mucocele including its history, epidemiology, etiopathology, clinical presentations, investigations, and current treatment.  
COVID-19 patients and sudden sensorineural hearing loss: a review
Authors: Swain Santosh Kumar
Published: March 2022

Coronavirus disease-19 (COVID-19) is a new pandemic caused by SARS-CoV-2 virus. COVID-19 patients often present with respiratory symptoms and death is the possible outcome. The potentiality for neuro-invasion by the SARS-CoV-2 is currently a subject of great debate. However, there is a paucity of information regarding the impact of the SARS-CoV-2 on the nervous system at the present moment. The impact of the coronavirus on the auditory system is little mentioned in the literature. Sudden sensorineural hearing loss (SSNHL) is a rare symptom associated with COVID-19 infection. This hearing deterioration could be attributed to the damaging effects of viral infections on the outer hair cells of the cochlea but the exact mechanism is still unknown. Awareness about this non-specific presentation like SSNHL in COVID-19 patients is often a challenge to a clinician for early management. Early identification of the SSNHL may be helpful for the isolation of the patient and also protect their infectiousness in the early period to prevent the spread of the disease. Early identification of hearing impairment is also helpful for early medical treatment of SSNHL which can save the hearing. This article reviews the epidemiology, etiopathology, clinical presentations, investigations, and treatment of SSNHL in COVID-19 patients. This review article surely makes a baseline from where further prospective studies can be designed for this rare clinical entity in COVID-19 patients as there are not many studies are done.
Diagnosis of obstructive sleep apnea
Authors: Bisht Shipra , Tanvika  , Banerjee Rini , Prasad P Narayana
Published: March 2022

Obstructive sleep apnea, a disorder in which people stop or restrict their breathing while sleeping, is becoming more common. This lead to restless, disrupted sleep, which can cause headaches in the morning and exhaustion in the afternoon. Obstructive sleep apnea affects people of all ages, however it is more common among persons over the age of 60. As a result, the correct diagnosis is essential for effective treatment. This review discusses a variety of diagnostic processes, including as screening questionnaires, sleep tests, and other diagnostic approaches, in order to demonstrate how correct diagnosis might aid in the development of a more effective treatment plan.
Evaluation and comparison of streptococcus mutans and scardovia wiggsiae from the predentate to permanent dentition using polymerase chain reaction
Authors: Sowjanya R  , Konde Sapna , Agarwal Manisha , Peethambar Preetha , Prasad Sahana N
Published: March 2022

Streptococcus mutans has been long associated with initiation of dental caries. Nevertheless, dental caries is also seen in its absence, indicating the role of another micro-organism.

To evaluate and compare the presence of Streptococcus mutans (S. mutans) and Scardovia wiggsiae (S. wiggsiae) in children from predentate to permanent dentition period using polymerase chain reaction.

80 children aged between 0 to 14 yrs., were divided into 8 groups of 10 each. Unstimulated salivary samples were collected from children of predentate to permanent dentition period with and without dental caries, which served as experimental and control groups respectively. The samples were compared and evaluated for S. wiggsiae & S. mutans. 2ml of unstimulated saliva samples were collected in a sterile 50ml graduated container & swab method was used to collect saliva from infants below 6-months of age & swabs were placed in MTM medium & stored at 20° C followed by DNA extraction procedure.

The present study showed that both S. mutans and S. wiggsiae were present in the predentate period & gradually increased upto mixed dentition period. However, both the organisms decreased in permanent dentition group. In primary, mixed & permanent dentition control groups, S. mutans counts was significantly greater than S. wiggsiae, whereas in the experimental group S. wiggsiae was significantly higher than S. mutans.

S. mutans could be the commensal and S. wiggsiae could be the major etiological organism in progression of dental caries.
Aesthetic finger prosthesis
Authors: Ajmire Samiksha , Karpathak Shilpi , Khandelwal Khushbu , Ajmire Surekha , Chaturvedi Apurva
Published: March 2022

Finger and partial finger amputations are commonly due to traumatic injuries. Rehabilitation of such patients with disabilities is a challenging task. The success of the prosthesis depends on the precision of planning the prosthesis, making the impression, carving the model and choosing the material that best suits the concerned circumstances. This clinical report portrays a method to fabricate silicone rubber prosthesis for a patient who has a partial finger loss caused due to trauma.
Overview of operative modalities and their functional outcomes for adult degenerative scoliosis: How to chose wisely!
Authors: Kulkarni Himanshu G , Khurjekar Ketan S , Kothari Siddarth , Hadgaonkar Shailesh R , Kothari Ajay R , Sancheti Parag K
Published: March 2022

Adult degenerative scoliosis presents with various symptoms, including back pain, leg pain, claudication, and radiological findings like coronal / sagittal imbalance. So In our study, we have put forth an algorithm to categorise the patients for suitable operative management.

This was prospective study of 30 patients. Patients with age 50 and above and ones who had no relief/worsening of symptoms after 6 months of conservative management were included. Patients were categorised into 3 groups. Patients were either treated with Focal Decompression / Decompression and long instrumented fusion with correction of deformity /Decompression only. MODI and SF36 scores were compared at the end of 2 years.

11 patients were categorised into group A, 15 into group B and, 4 patients who had significant co-morbidities and had very high risk for surgery were categorised into group 3. There was significant (p <.001) improvement in average MODI scores in both group A and group B at the end of 2 years. Improvement was seen in average MODI scores of patients in group 3, but it was not statistically significant. SF-36 score showed significant improvement in Group A and group B at the end of 2 years (p <.001). Patients from group 3 also showed improvement in average scores, but that was not significant.

Not every case needs long stabilization, focal decompression only also gives satisfactory outcome in properly selected patients. In patients operated by Instrumented fusion, Sagittal balance also plays a crucial role in functional outcome.
Fixation of acetabular fractures with quadrilateral plate involvement using intrapelvic reduction and buttress plate via modified stoppa approach: A clinico-radiological and functional outcome evaluation
Authors: Das Ayon , Das Arijit , Bera Dhananjoy , Samanta Swarnendu
Published: March 2022

Acetabular fractures with quadrilateral plate involvement form a heterogeneous group of fractures which are not specifically defined by any current classification system. Surgical treatment of these fractures poses a challenge to Orthopaedic surgeons. The aim of this study was to evaluate the efficacy, safety and outcomes of the fixation technique by using IRBP for acetabular fractures with quadrilateral plate involvement via single modified Stoppa approach.

A total of 30 patients with acetabular quadrilateral plate fracture, selected between January 2016 to June 2019, were managed by IRBP via modified Stoppa approach. This was a prospective study and all patients were followed up to a minimum of 2 years. The primary outcome measures were reduction quality and functional outcome which were evaluated according to Matta’s radiological criteria and modified Merle d’Aubigné and Postel score respectively. Secondary outcomes were intra-operative conditions such as operative time and blood loss and post-operative complications.

Anatomic reduction was obtained in 22 (73.3%), Imperfect in 6 (20%), and Poor in 2 (6.7%) cases. The modified Merle d’Aubigné and Postel score outcomes were Excellent to Good in 25 (83.3%) patients, Fair in 3 (10%), and Poor in 2 (6.7%) with the mean score being 16.07 ± 2.68. 21 (70%) patients did not have any complications. None of the cases had quadrilateral screws entering the hip joint.

The use of IRBP system is an effective and safe choice for acetabular fractures with quadrilateral plate involvement done via modified Stoppa approach as it has low rate of complications, addresses multiple fractures of acetabulum through a single approach and provides good functional and radiological outcomes over long term.
Functional and radiological outcome of gartland type 2 and 3 supracondylar fracture humerus in children treated by percutaneous pinning
Authors: Rajput Shashwat Singh , Sharma Jayant , Mustafa S.A
Published: March 2022

Supracondylar fracture of Humerus is the commonest injury around the Elbow in children. It constitutes about 60% of all the fractures about the Elbow in children.

The aim of the present study is to evaluate the results of percutaneous pinning of unstable or irreducible Type II and III Supracondylar Humeral fractures in children.

A prospective study was conducted on 30 children, taking into consideration age, gender, affected side, mode of injury, type of fracture, Gartland classification of fractures, time duration between injury and surgery, postoperative complications and radiographic and clinic variables.

: The median loss of motion was 5 degrees and the median change in carrying angle was 4 degrees. All patients had satisfactory results in terms of Loss of Carrying angle, Limitation of Elbow flexion and Flynn’s grading. There were 19 patients that had excellent ratings, 9 patients had good ratings and lastly only 2 patients had fair Flynn’s ratings. There was only 01 patient suffering from neurological deficit and only 01 patient from pin track infection.

Percutaneous fixation with two crossed Kirschner wires leads to good functional and radiological outcome of Gartland type 2 and 3 supracondylar fracture humerus in children.
Treatment efficacy using occlusal splint for anterior disc displacement without reduction of temporomandibular joint
Authors: Divakar Nimisha , Vengal Manoj , Ahsan Auswaf
Published: March 2022

Management of TMDs with occlusal splint is a reversible, non- invasive modality which causes minimum damage to tissues, when compared to other irreversible treatment modalities. Objectives of this study is to assess the effectiveness of flat occlusal splint in patients with anterior disc displacement without reduction by evaluating reduction in pain and improvement in mouth opening.

35 participants with mean age 35 years who does not have any systemic diseases and not undergoing treatment for ADD without reduction were selected for study. After recording pain score on VAS scale and maximum mouth opening, flat occlusal splint was fabricated for maxillary arch. Patients were advised to wear the splint for all the time except on meal times. Maximum mouth opening and pain score were again evaluated after 3 weeks.

Statistical results showed that there is highly significant reduction in pain score and increase in maximum mouth opening. Mean VAS score before treatment was 7.26±0.88. After treatment with splint therapy, VAS score was reduced to 2.94±1.41. The mean value of maximum mouth opening before treatment was 23.09±4.25. After treatment with splint therapy, it was increased to 30.37±5.43. Both parameters had p value <0.001, which is highly significant statistically.

Significant reduction in pain score and improvement in mouth opening noted after using flat occlusal splint in patients having ADD without reduction. However, further studies are needed on a long term basis for better results.
Non-surgical management of a large periapical lesion using triple antibiotic paste: A case report
Authors: Kumar Dhirendra , Mohanty Ashok Kumar
Published: March 2022

Root canal infection is considered to be a polymicrobial infection, consisting of both aerobic and anaerobic bacteria. Because of the complexity of the root canal infection, it is unlikely that any single antibiotic could result in effective sterilization of the canal. A combination of antibiotic drugs (metronidazole, ciprofloxacin, and minocycline/doxycycline in this case) is used to eliminate bacteria, which are possible sources of endodontic lesions. Case report describes the nonsurgical endodontic treatment of maxillary right central and lateral incisor with large periapical lesion. A triple antibiotic paste was used for 4 months at monthly interval. After 4 months, teeth was asymptomatic and was obturated. Complete periapical healing was observed at the 24-month recall. This report confirms that for treatment of a large periapical lesion it is not always necessary to do surgical treatment and even cyst-like periapical lesions heal following conservative endodontic therapy. The results of the case show that when most commonly used medicaments fail in eliminating the symptoms, then a triple antibiotic paste can be used clinically in the treatment of teeth with large periapical lesion.
Noticias del BID: Vol. 12, no. 12, diciembre 1985
Authors:   Banco Interamericano de Desarrollo
Published: March 2022

Noticias del BID, publicación mensual que tiene por objetivo informar acerca de las actividades del Banco Interamericano de Desarrollo.
Paradoxes of the methodology of modern political science: possibilities and limits
Authors: Karadhe Tatiana V.
Published: March 2022

The article attempts to consider the reasons for limiting the analytical and predictive capabilities of the methodology of modern political science. On the basis of various approaches, the factors that hinder the objective analysis and forecasting of the political are analyzed. The ontological, epistemological and praxiological aspects of the analysis of this problem are presented. It is noted that the formation of a global system is accompanied by the emergence of new properties, including interdependence, increased turbulence and chaotic behavior, cascading effects of changes, the growth of fluctuations and emergent manifestations that increase uncertainty and instability. At the same time, the research apparatus of the methodology of political science does not reflect the complexity, dynamics and diversity of the new emerging interconnections of the open global system, which necessitates its revision, activation of its further development, transition to a new constructivist paradigm. The article examines the importance of interdisciplinarity in the formation of new areas of political science, as well as the role of transdisciplinarity in the formation of new research strategies. The impossibility of forecasting based on successful models and methods in the past, extrapolation of the system of causal relationships of local systems in a state of relative stability to the prediction of open unstable systems is noted. The praxeological analysis allowed us to consider the features of the process of interpreting the results of analytical and predictive activities, the importance of the interest of political actors in the implementation of the results of scientific activity in political practice.
Methods of Improving Technical and Functional Characteristics of Serial Budget Microprocessor Platforms
Authors: Lebediev Vladyslav A. , Laktionov Ivan S. , Vovna Oleksandr V. , Kabanets Maryna M. , Sahaida Pavlo I. , Dobrovolska Liudmyla O.
Published: March 2022

The relevance of the research is due to the fact that one of the prerequisites for the implementation of Internet of things and Wireless sensor network technologies is the reliable operation of the involved information and measurement systems as parts of the automation and digitalization systems on the rights of subsystems. Thus, the main purpose of the article is to substantiate scientific approaches to increasing the reliability of budget serial microcontroller boards as parts of information and measurement systems by developing methods of improving their technical and functional characteristics. Basic research methods are: methods of critical analysis and logical generalization; methods of computerized monitoring of electrical parameters; methods of experiment planning; methods of computer analysis of measurement results; approaches to experimental testing of information and measuring equipment. The main results of the article are as follows: the current state of scientific research and practical developments on ways to improve the technical and functional characteristics of microprocessor platforms has been analysed; the stabilization characteristics of the output voltage of the microprocessor platform have been investigated; the temperature dependences of the microcontroller at different denominations and types of load have been obtained; the priority areas for further research have been substantiated.
Interaction Model of the Cabin of Combined Sugarcane Harvesters
Authors: Liu Sha , Tan Yu , Wu Chunyang
Published: March 2022

Owing to visual blind spot areas and occasional negligence, combined sugarcane harvester drivers often make mistakes in field operation, some of which evolve into major accidents. To improve drivers’ perception of and response to warning information, this paper explores the optimal interaction mode of warning information for the cabin of combined sugarcane harvesters. A series of experiments were carried out on a stationary driving simulator to verify the driver experience and alarm efficiency of three modes of warning information, namely, text, audio, and image, as well as their dual-channel modes. The physiological data, such as electrodermal activity (EDA), photoplethysmography (PPG), and electroencephalogram (EEG), of eight subjects were collected through the experiments. On this basis, the cognitive load of drivers was analyzed under different modes of warning information. The motion feedback time was recorded to parse the driver’s recognition rate and reaction speed to the warning information, and the eye movement was captured to analyze the driver’s attention distribution. The results show that the recognition rate under the dual-channel mode of visual and audio is higher than that of the single-channel mode of text or image. The addition of the visual warning information (text or image) to the audio information reduces the attention distribution time, and the best reduction effect is achieved in the image plus voice mode. The EDA indices of latency, amp sum, and mean half decay time fully reflect the effect of alarm information modes on the subjects’ reaction speed and emotional stimulation. The image plus voice mode has the fastest response speed, smallest response to stimuli, and the best ability for emotional recovery than the other modes. The eye movement, some EDA indices, and EEG are more sensitive to stress reaction, while the HRV is not sensitive for analyzing drivers’ stress to the stimuli of warning information in a short time. The research results lay the basis for designing a more efficient and accurate reminder mode of warning information for combined sugarcane harvesters.
Ensemble Residual Network Features and Cubic-SVM Based Tomato Leaves Disease Classification System
Authors: Özyurt Fatih , Sert Eser , Avci Derya
Published: March 2022

The need for automatic disease detection applications that can help farmers in the detection of agricultural product diseases is increasing day by day. Convolutional Neural Network (CNN) is a very popular field in image processing, recognition, and classification. It is seen that CNN architectures are used in the determination of agricultural products. In this study, 3 different ResNet architectures of the features automatically are used in the detection of tomato diseases. The most efficient features obtained from these architectures have been obtained by the NCA algorithm again. The features obtained have been trained with the Cubic SVM machine learning algorithm. Tomato leaves belonging to a total of 10 classes have been trained at 80% and a test performance rate of 98.2% has been achieved.
A Rapid Advancing Image Segmentation Approach in Dental to Predict Cryst
Authors: Sivasankaran Prasath , Dhanaraj Karthigarani
Published: March 2022

A teeth X-rays image exhibits low intensity & irregular illumination, resulting in loss of solid distinction among distinct sections of the tooth, making tumor separation time-consuming. That isophote curvature is the line that connects pixels of the same brightness. Every isocenters is related to every isophotes curvature line. That Maximal IsoCenters (MIC) serves as the starting point for the rapid marches technique's model-based segmented. Its Fastly Marching Methodology (FMM) was similar to Dijkstra's algorithms in that it takes the quickest route from of the promoter regions, wherein data simply travels outwards. It operates in a methodical way to speed things up, and that's a one-pass approach although each spot is mostly just handled once. As a result, combining prototypes with the feature-based categorization of dentistry X-rays images offers a lot of promise in terms of diagnosing tooth disorders & helping to design electronic machines. This segmentation and classification technique computerizes or automates the testing process, allowing for the monitoring of a significant number of patients with much the same exactness. Rising machines aid in the production of fast and effective outcomes. Computer's systems make it feasible to expand patient safety to far places by allowing for speedier interaction.
Analysis on Chlorophyll Diagnosis of Wheat Leaves Based on Digital Image Processing and Feature Selection
Authors: Song Yufei , Li Shiwu , Liu Zhiguo , Zhang Yuekui , Shen Nan
Published: March 2022

Crop nutrition measurement is of great significance in agricultural practice, especially in variable rate fertilization. The chlorophyll content, an important indicator of nitrogen nutrition in crops, largely depends on crop growth and development, photosynthesis, and crop yield, and plays an important role in the monitoring of crop growth. This paper tries to detect the chlorophyll content of wheat quickly, using the digital image processing technology. Specifically, a feature selection method was developed based on wrapper and light gradient boosting machine (LGBM), and combined with logistic regression (LR) to predict the chlorophyll content of wheat. The results show that: the optimal model is the combination between the 17 image evaluation indices screened by LGBM and the LR prediction model; the optimal results were coefficient of determination (R2) of 0.728, and root mean square error (RMSE) of 4.979. The optimal model can predict the chlorophyll content of wheat accurately based on digital images in field prototype.
Purification of Tomato Bushy Stunt Virus Particles by One-Step Hydroxyapatite Column Chromatography
Authors: Tleukulova Zh. , Stamgaliyeva Z. , Dildabek A. , Mukiyanova G. , Omarov R.T.
Published: March 2022

The main aim of this work was to develop a time-saving and cost-effective purification method of infectious plant viral nanoparticles. Virions of Tomato bushy stunt virus (TBSV), which is a member of Tombusvirus genus, were purified by one-step Bio-gel HT Hydroxyapatite (HA) column chromatography. Extracts from Nicotiana benthamiana plants infected with TBSV were directly loaded onto the HA column and eluted by 10 mM sodium phosphate buffer (pH 6.8). A specificity of virions has been confirmed by immunoblotting and electron microscopy. Homogeneity of virions was tested by SDS-PAGE, where only 41 kDa polypeptide bands referring to the capsid protein of TBSV were detected by Coomassie staining. The biological infectious activity of a purified material was demonstrated by observing TBSV-specific symptoms observed in N. benthamiana plants at 7‒10 days of post-inoculation (dpi). Moreover, purified virions were used for immunization of the BALb/c mouse to raise primary antibodies against the TBSV virus. Our results show that in low concentrations of sodium phosphate buffer total proteins extracted from infected plants adsorb to HA sorbent, while viral particles do not adsorb to the HA matrix and flow throw column due to Ca2+ ions implicated in TBSV virions’ structure. This highly effective and simple virus purification protocol can also be used for the isolation of other plant virions.
A Comparative Study of the Probability and Statistics Curricula in the High School Mathematics Textbooks of Vietnam and Germany
Authors: Chi Nguyen Phuong
Published: March 2022

An international comparative study of mathematics textbooks is essential in identifying trends in international mathematics education, developing textbooks and improving the quality of teaching and learning in mathematics. This study analyses and compares the contents of the probability and statistics curricula in the high school textbooks of Vietnam and Germany. It highlights the similarities and differences in the contents and the way they are presented, consolidated and deepened in textbooks of the two countries. The probability and statistics curricula in Vietnamese textbooks are much less than that of German textbooks. The Vietnamese textbooks focus on the mathematical content whereas the German textbooks focus on applications of the content in real life. Vietnamese textbooks tend to force students to accept probability and statistics knowledge while German textbooks encourage students to explore knowledge. Because of this, contexts relating to the contents in German textbooks are more detailed and more natural. German textbooks mainly use an inductive approach to present the contents whereas Vietnamese textbooks often use a deductive approach. In addition, German textbooks unlike those of Vietnam, always take advantage of realistic situations in exploring the contents, encourage co-operative learning and promote statistical reasoning by implementing several project works and provide an opportunity for practical experience and experiment by using the simulations of probability and statistics situations. The comparison shows the strengths of probability and statistics contents in German textbooks that Vietnamese textbooks can learn for the development of textbooks in future.
WHOLE SORGHUM FLOUR PROCESSED AS COOKIES MAINTAINED BIOACTIVE COMPOUNDS AT STORAGE
Authors: PANSINI DÉBORA DAVID , PANSINI DÉBORA DAVID , NASCIMENTO ROSIANE COSME , QUEIROZ VALÉRIA APARECIDA VIEIRA , FIGUEIREDO JOSÉ EDSON FONTES , MOREIRA DA SILVA ÉRIKA MADEIRA , MORAES ÉRICA AGUIAR
Published: March 2022

O sorgo é um cereal em destaque devido aos seus compostos fenólicos bioativos com efeitos protetores da saúde dos consumidores. Este estudo teve como objetivo avaliar as características tecnológicas, sensoriais e compostos de biscoitos elaborados com farinhas de sorgo em diferentes proporções e o efeito do armazenamento dos biscoitos no teor de compostos fenólicos e na capacidade antioxidante. Os biscoitos foram preparados com farinha integral do genótipo de sorgo BRS 506 e amido de milho nas proporções de 50 (50 SF), 75 (75 SF) e 100 (100 SF) g de sorgo / 100g de farinha total. Medidas de biscoitos, análise sensorial e composição química foram determinadas. Os compostos fenólicos foram compensados durante 45 dias de armazenamento.A farinha de sorgo aumentou o fator de expansão dos biscoitos, especialmente para 75SF e 100 SF. Com exceção da textura e da intenção de compra, os biscoitos de sorgo têm índice de aceitação superior a 70%. A farinha de sorgo melhorou como propriedades nutricionais e dados maiores fenólicos totais, taninos, antocianinas e capacidade antioxidante em relação ao controle. Eles mantiveram o conteúdo fenólico total e aumentaram a capacidade antioxidante por 45 dias, principalmente devido a 50 g ou 75 g de farinha de sorgo. Esses resultados indicam que a farinha de sorgo integral é uma opção para a indústria de alimentos em busca de experimentar novos produtos com benefícios à saúde.
Benefits and Difficulties of Integrating Mobile Technologies in the Academic Learning
Authors: Mâţă Liliana , Dobrescu Tatiana
Published: March 2022

Exploring students' perceptions of the advantages and disadvantages of mobile technologies (MT) is necessary in the dynamic context of their increasing use in learning. The data obtained from 532 students from a state university were analyzed. The students mentioned three advantages and three disadvantages of using mobile technology in the learning activity. Based on the content analysis, the main categories referring to the benefits and difficulties of using MT were identified. The main categories in terms of benefits are: technological advantages, information using mobile technologies, efficient communication, opportunities for educational process, personal development, facilities at the economic and environmental level. Referring to the difficulties of MT, there was identified: negative influence on personal development, technological difficulties, damaged information, diminishing communication and socialization abilities, the negative effects on the educational process, economic, ecological and ethical disadvantages. The novelty of the study consists in highlighting the importance of MT integration in achieving academic learning activity.
Psychological-Pedagogical Components of the Children’s Speech Environment With Autistic Disorders of Senior Preschool Age
Authors: Bazyma Nataliia , Fihol Nataliia , Malyna Olena , Serheieva Valentyna , Lopatina Hanna , Koropatova Oksana
Published: March 2022

Education of initiative and desire for self-realization, in our opinion, is possible only if the emergence and constant reinforcement of interest. We offer when choosing tasks and games to focus on compliance with the following requirements: interesting topics for the child; bright props; compliance with the topic being studied; focus on the child's practical experience; emotional significance. In addition, the features of the mental and behavioral sphere of children with autistic disorders must be taken into account : lack of mental activity; unevenness, the partiality of intellectual development; violation of the interaction of mental functions; lack of lively curiosity, interest in the new; difficulties of voluntary learning, purposeful solution of really arising problems; violation of purposefulness, difficulty concentrating; quick exhaustion and oversaturation with any purposeful activity; negative reaction or no reaction at all when trying to draw attention to the objects of the surrounding reality; difficulties at understanding time, duration, determining the sequence of events, causes and consequences; difficulties in symbolization, transfer of skills from one situation to another, etc. Corrective work on the development of speech activity and communicative behavior is carried out in everyday life, during live communication with the child about his domestic, playful and cognitive interests, in the process of role-playing or theatrical games (if available), in drawing, modeling classes, design, manual labor, speech development, during the formation of elementary mathematical concepts, physical and musical education, during individual correctional work, etc.
Comparative Study of Resistance Training with Different Frequency on the Selected Machine Exercises Among University Males
Authors: Azeem Kaukab
Published: March 2022

The purpose of this study was to compare the resistance training groups with different frequency in a week on the selected machine exercises among university males. Method: Hundred participants selected randomly to join and part of this research study.
Participant’s ages were in the range of 18-24 years, forty minutes of training per session. These subjects separated into two groups such as; group-A (N=50, two days of training in a week for eleven weeks), group -B (N=50, four days of training in a week for 5 and half weeks). Both the groups had gone through 22 resistance-training sessions. The impact of resistance training protocols with different frequency in a week on the groups in the selected exercises i.e. (leg press, leg extension, leg curls, high pull downs, sitting shoulder press, rear delt, sitting extensions and arm curls) had shown significant improvement. Furthermore, interestingly the group-A had shown greater performance in all the selected resistance training exercises. Group-A performance with regard to the increase by percentages; Sitting leg press performance increased by percent (18.27%). Leg extension performance was increased by percent (15.12%). Leg curls (increased by 14.22%). Lat pull down (increased by 12.78%). Sitting shoulder press (25.16%). Rear delt (increased by 10.04%). Triceps extension (performance increased by 7.83%). Arm curls performance increased by (8.74%). These findings were consistent with the previous studies they are as follows; (M. S. Faigenbaum et al, 1997). In a previous research, study it was investigated with regard to the training frequency comparison for the parallel bench press exercise 03 sessions is profound to 1 or 2 sessions (ACSM 1998).
The Latest Trends in The Professional Training of Masters in the Field of Engineering and Technology
Authors: Kobernyk Oleksandr , Yashchuk Serhii , Yermakova Svitlana , Chmyr Victor , Bukina Tetiana , Romanenko Viktor
Published: March 2022

The article talks about the latest trends in the professional training of masters in the field of engineering and technology. Its goal is to highlight and summarize these trends, to find out the general and the excellent, which can be used for the further development of multistage of higher education. Mostly, we used theoretical methods - selection, analysis, generalization of the latest trends in modern scientific and methodological literature, as well as elements of a comparative typological analysis of educational systems. In the course of the study, the authors found out: a characteristic feature of master's programs in Western European countries and the United States is the profile specialization and duration of study, which is determined by the requirements of the state and the system of organizing training in a particular university. Education at this stage is created according to individual programs, where the student and the scientific adviser participate jointly. An analysis of the training of masters in the field of engineering and technology in foreign countries indicates that the master's level in differentiation is preliminarily acquired on the basis of the obtained bachelor's level: master-practitioner and master-scientist. When preparing masters, national traditions of countries are taken into account and special attention is paid to practice. International significance of the article: the article summarizes the latest changes in the professional training of masters in the field of engineering and technology, which can be used in reforming the educational systems of developing countries. Also, the article is of interest to historians of education and specialists in comparative typological education.
Analiza i charakterystyka tendencji rozwojowych oraz przemian w strukturze polskiego przemysłu w latach 1950–1970
Authors: Klimiuk Zbigniew
Published: March 2022

Koncepcja selektywnego rozwoju polskiego przemysłu w perspektywie lat 70. XX w. zakładała dokonanie istotnych przekształceń strukturalnych w przemyśle związanych z unowocześnieniem produkcji przemysłowej. Najbardziej intensywne przemiany strukturalne miały miejsce w pierwszym etapie uprzemysłowienia i związane były z budową podstaw względnie rozwiniętego kompleksu przemysłowego. Intensywność zmian strukturalnych w tym okresie, mierzona średnim współczynnikiem stosunkowych przekształceń strukturalnych, była niezwykle wysoka. W latach 1960–1970 intensywność przemian w gałęziowej strukturze produkcji była znacznie mniejsza niż w okresie poprzednim. W dalszym ciągu znaczny wzrost udziału w globalnej produkcji przemysłowej wykazywały branże przemysłu maszynowego i chemicznego, chociaż wskaźniki wyprzedzenia tempa wzrostu wymienionych gałęzi w stosunku do tempa wzrostu przemysłu ogółem były mniejsze niż w latach 1950–1960. W miarę przechodzenia do kolejnych faz rozwoju przemysłowego coraz większego znaczenia nabierały przemiany wewnątrzgałęziowej struktury produkcji w obrębie poszczególnych przemysłów, zwłaszcza w obrębie tzw. gałęzi wiodących. Strukturalne aspekty wzrostu gospodarczego i przemysłowego nie stanowiły przez długi okres przedmiotu szczegółowych badań ekonomicznych, zwłaszcza z punktu widzenia traktowania tych przemian jako samodzielnego czynnika współczesnego rozwoju gospodarczego. Wyspecjalizowany rozwój przemysłowy był traktowany jako warunek utrzymania produkcji na wysokim poziomie technicznym, a tym samym jako warunek rozwoju wymiany handlowej i współpracy w dziedzinie produkcji przemysłowej.
What prognostic information does flow cytometry provide in canine B-cell lymphoma?
Authors: Haythornthwaite Benjamin
Published: March 2022

PICO question

In dogs with B-cell lymphoma, does the use of flow cytometry provide useful prognostic information?

 

Clinical bottom line

Category of research question

Prognosis

The number and type of study designs reviewed

Twelve papers were critically reviewed. All were cohort studies

Strength of evidence

Moderate

Outcomes reported

There are multiple potential prognostic indicators in canine B-cell lymphoma that flow cytometry can be used to evaluate, including lymphoma stage, survival time and time to progression. There is promising evidence for the use of percentage expression of CD25 and Ki67 cellular markers in providing prognostic information in canine B-cell lymphoma and these should be assessed further in clinical practice. Flow cytometry has also been shown to be useful in assessing bone marrow infiltration and providing prognostic information relating to this. There is also evidence for the prognostic value of measuring expression of class II MHC and CTLA-4 cellular markers, peripheral lymphocyte / monocyte ratio, nodal regulatory T-cell populations and the ratio between T and B lymphocytes in extranodal locations. Peripheral regulatory T-cell populations and cellular size were also assessed, however further investigations are required before confirming their prognostic value

Conclusion

Flow cytometric analysis offers useful measures of prognosis in canine B-cell lymphoma, although further validation is required before introducing their routine use. Percentage expression of CD25 and Ki67 cellular markers from lymph node aspirates of dogs with B-cell lymphoma appear to be promising prognostic indicators in clinical investigations, however this needs to be translated into clinical practice. While there is evidence for the prognostic value of bone marrow infiltration measured flow cytometrically, expression of class II MHC and CTLA-4, peripheral lymphocyte / monocyte ratio, nodal regulatory T-cell populations and the ratio between T and B lymphocytes in extranodal locations, these need to be further investigated before introducing into clinical practice. As new antibodies against cellular targets in dogs become available, it is likely that flow cytometry will become even more useful in providing prognostic information

 

How to apply this evidence in practice

The application of evidence into practice should take into account multiple factors, not limited to: individual clinical expertise, patient’s circumstances and owners’ values, country, location or clinic where you work, the individual case in front of you, the availability of therapies and resources.

Knowledge Summaries are a resource to help reinforce or inform decision making. They do not override the responsibility or judgement of the practitioner to do what is best for the animal in their care.
EDUCATION 4.0: HYBRID LEARNING AND MICROLEARNING IN A SMART ENVIRONMENT
Authors:   Doctor of Natural Sciences, Electrical Engineering, and IT Department, SRH Vocational Training Center, Neckargemünd, Germany, Mekacher Leila
Published: March 2022

The term "4.0" refers here, as in all areas whether Industry 4.0, Work 4.0, or Society 4.0, to the paradigm of digitalization and support through new technologies. In the last few years, education and training are becoming more closely related to the labor market, and so the goal is to foster competent learners to meet the core skills for life and work in the 21st century. Building such a future-ready education system requires the design of curricula, that impart the necessary knowledge and skills for the modern workplace. The various pedagogical and technological innovations in recent years have created new concepts of learning environments, that optimize learners' ability to learn. They are commonly referred to as "smart learning environments". Innovative education based on advanced technologies should focus on stimulating thinking and creativity and address the individual differences of learners. The purpose of this paper is twofold. First, combines some educational concepts such as micro and hybrid learning with the support of immersive technologies to develop smart learning environments for a personalized and gamified seamless learning experience. Second, demonstrates how the concept of Micro-hybrid-immersive learning enables a seamless transition between school and the world of work and achieves educational inclusion.