bluuebunny/crossref_metadata_2025 huggingface dataset:
POLÍTICAS DE INCLUSÃO EM EDUCAÇÃO: DISCUTINDO A IMPORTÂNCIA DA FORMAÇÃO DE GESTORES PARA A DIVERSIDADE
Authors: Santos Mônica Pereira dos , Senna Manoella
Published: September 2020

Este artigo tem por objetivo apresentar e discutir, com base na perspectiva omnilética (SANTOS, 2013), os sentidos das legislações relativas ao tema da inclusão social, capturados por meio de levantamento exploratório no site do Senado Federal brasileiro, e, dentro disso, da inclusão em educação. Para tanto, apresenta uma pesquisa desenvolvida em parceria com uma Gerência de Educação no município do Rio de Janeiro entre os anos de 2014 e 2017, cuja metodologia foi qualitativa do tipo pesquisa-ação e que teve como foco a formação continuada de sua equipe de gestores e a autorrevisão de culturas, políticas e práticas de inclusão em educação. Discute os dados concernentes às concepções de inclusão em educação dos gestores participantes da pesquisa em um diálogo com os resultados do levantamento exploratório, que demonstrou uma concepção ainda estrita sobre o processo de inclusão, porque focalizada, majoritariamente, nos grupos de pessoas com deficiência. Sem deixar de reconhecer a importância desse movimento à emancipação das pessoas com deficiência brasileiras, o artigo argumenta acerca da importância do investimento em formação continuada de gestores da educação no que tange aos processos de inclusão/exclusão de todos na escola.
Government Policy, Factor Market Distortion and Structural Transformation
Authors: Liu Jianfang
Published: September 2020

Demand-driven economic structural transformation is mainly realized through the Engel Effect, and different consumption has different income elasticity. This article attempts to explain the effects of taxation, technological progress and factor price distortions on economic structure by introducing government policies and capital labor price distortions into the multi-sectorial model. The results showed that the share of agricultural labor decrease when the tax rate decreased or technological progress occurred and the share of service labor increased when the non-homothetic of utility function was stronger. Similarly, the distortion of capital and labor factor prices will also affect the structural transformation, and the relationship between the two is opposite. When the distortion of manufacturing sector factor prices increases, the structural transformation will be accelerated. However, the structural transformation slows down as the distortion of factor prices in service industry increases.
Psicoterapia racional emotiva
Authors: Amorós Víctor
Published: September 2020

En el presente artículo el autor realiza una síntesis didáctica sobre los orígenes, fundamentos, características y la técnica de la terapia racional emotiva de Albert Ellis. Se explica cómo las personas crean sus propios trastornos emocionales y conductuales por sus prejuicios y pensamientos equivocados. Se concluye afirmando que son las ideas irracionales las que originan en gran medida las neurosis. El trabajo se detiene en la actitud del terapeuta quien aplica una técnica directiva reforzando los componentes cognitivos del paciente.
Análisis evolutivo y diferenciativo de la percepción rorschach a través de los factores de localización
Authors: Jiménez Gómez Fernando , Sánchez Crespo Guadalupe
Published: September 2020

Este estudio versa sobre la evolución de diferentes factores de personalidad a través de los engramas aperceptivos del Psicodiagnóstico de Rorschach en diferentes grupos de edades de la adolescencia y de la madurez, desde los ll años hasta los 60 inclusive, en una población de su jetos españoles dentro de la amplia y variada geografía peninsular. La muestra está referida sobre 526 adolescentes y 300 adultos diferenciados y analizados por sexos, con 424 varones y 402 mujeres. La media de edad de los adolescentes es de 15 años y 6 meses y la de los adultos de 37 años y dos meses. De los diferentes factores del Psicodiagnóstico de Rorschach, hemos centrado nuestra investigación en los factores propios de la Categoría de Localización.
Investigación en psicoterapia
Authors: Villegas Orlando
Published: September 2020

El artículo reflexiona sobre la psicoterapia como ciencia y como arte, su definición, las consideraciones éticas y metodológicas de la investigación en psicoterapia, incluyendo variables del terapeuta, del paciente, del proceso y del diseño. Se presentan, además resultados de una revisión de investigaciones sobre el método terapéutico, sobre el paciente, sobre el terapeuta y sobre el tiempo como variables independientes, arribándose a una serie de conclusiones.
Dificultades en el proceso de identificación y bajo rendimiento escolar visto a través del psicodiagnóstico de Rorschach
Authors: Garrido-Lecca Magally , Figueroa Maritza
Published: September 2020

La presente investigación se refiere a un estudio de 71 niños (44 niños y 27 niñas) que presentaban un bajo rendimiento escolar. Utilizando el psicodiagnóstico de Rorschach, las autoras identifican signos que presentan estos niños y que son estadísticamente significativos como: bajo M, A%> íO%, bajo FM y shock kinéstesicos en las Láminas I, ll, III y IX. Asimismo se constató que estos niños muestran dificultades en la identificación sexual y bloqueos. Se concluye que el Psicodiagnóstico de Torschach es un buen instrumento para evaluar a niños con bajo rendimiento escolar.
Ciclo vital, crianza y educación del niño en la época incaica
Authors: Majluf Alegría
Published: September 2020

La autora basada en información proporcionada por los cronistas e historiadores describe el curso, del desarrollo, la crianza y educación del niño en la época Incaica.
Estilos fenomenológicos de evocación de recuerdos autobiográficos en individuos con depresión mayor
Authors: Lolich María , Azzollini Susana
Published: September 2020

La evocación de recuerdos autobiográficos se caracteriza por presentar distintos compo­ nentes fenomenológicos. Dada la ausencia de trabajos previos realizados en poblaciones hispanoparlantes, se realizaron 34 entrevistas en profundidad a individuos con y sin tras­ torno depresivo mayor de la ciudad de Buenos Aires (Argentina). Fueron explorados los componentes fenomenológicos presentes en la evocación de recuerdos autobiográficos significativos. Los datos fueron analizados cualitativamente por medio de la Teoría Fun­ damentada en los Hechos. Durante el análisis descriptivo, se detectaron siete categorías fenomenológicas emergentes del discurso. Del análisis axial y selectivo fueron identificados dos ejes discursivos: retórico-proposicional y especificidad-generalidad. Las implicancias, en la regulación afectiva, derivadas de la asunción de un estilo amodal o multimodal de proce­ samiento de información autobiográfica merecen mayor atención.
Desempeño de reactores empacados con marlo de maíz (Zea mays) en la remoción de hierro contenido en drenajes ácidos de mina
Authors: Hernández Angie Lorena , Vásquez-Ochoa Olga Yaneth , Roldan-García Fabio Augusto , Lobo Jairo Antonio Cubillos , Pineda Gerardo Andrés Caicedo
Published: September 2020

Se evaluó la capacidad del marlo de maíz (Zea mays) para remover hierro contenido en drenajes ácidos de mina (DAM) de carbón, en reactores de lecho empacado, a escala laboratorio. Los ensayos tuvieron una fase de filtrado de efluente, a través del lecho, a un caudal de 5 mL×min-1 y un lavado de columna, con agua destilada, a fin de remover lo débilmente retenido por la biomasa. Las variables evaluadas fueron: (i) modificación del marlo con hidróxido de sodio (NaOH) o ácido cítrico (C₆H₈O₇) y (ii) concentración de hierro en el DAM de 500 ppm, 1,000 ppm y 2,000 ppm. Simultáneamente, se hicieron ensayos, bajo las mismas condiciones, pero, con lavados de agua destilada al marlo, cada 400 mL de DAM filtrado, con el fin de evitar la saturación del sistema. El efluente tratado se monitoreó mediante mediciones de pH y hierro (espectroscopia de absorción atómica). Las biomasas se caracterizaron fisicoquímicamente, al iniciar y al finalizar el proceso, mediante espectroscopia infrarroja con transformada de Fourier (FTIR). En general, el pH del DAM jugó un papel muy importante en la capacidad de remoción del metal y se obtuvo mejores porcentajes de remoción de hierro utilizando marlo modificado con NaOH, incluyendo lavados esporádicos durante el proceso.
The maximum number of triangles in a graph of given maximum degree
Authors: Chase Zachary
Published: September 2020

Maximizing or minimizing the number of copies of a fixed graph in a large host graph is one of the most classical topics in extremal graph theory. Indeed, one of the most famous problems in extremal graph theory, the Erdős-Rademacher problem, which can be traced back to the 1940s, asks to determine the minimum number of triangles in a graph with a given number of vertices and edges. It was conjectured that the mnimum is attained by complete multipartite graphs with all parts but one of the same size whilst the remaining part may be smaller. The problem was widely open in the regime of four or more parts until Razborov resolved the problem asymptotically in 2008 as one of the first applications of his newly developed flag algebra method. This catalyzed a line of research on the structure of extremal graphs and extensions. In particular, Reiher asymptotically solved in 2016 the conjecture of Lovász and Simonovits from the 1970s that the same graphs are also minimizers for cliques of arbitrary size.

This paper deals with a problem concerning the opposite direction: _What is the maximum number of triangles in a graph with a given number $n$ of vertices and a given maximum degree $D$?_ Gan, Loh and Sudakov in 2015 conjectured that the graph maximizing the number of triangles is always a union of disjoint cliques of size $D+1$ and another clique that may be smaller, and showed that if such a graph maximizes the number of triangles, it also maximizes the number of cliques of any size $r\ge 4$. The author presents a remarkably simple and elegant argument that proves the conjecture exactly for all $n$ and $D$.
Evaluation of physical-mechanical properties of self-adhesive versus conventional resin cements
Authors: Borges Maria Helena Rossy , Dias Carmen Gilda Tavares , Alencar Cristiane de Melo , Silva Cecy Martins , Esteves Renata Antunes
Published: September 2020

Aim: The purpose of this study was to compare the microhardness, diametral tensile strength, compressive strength and the rheological properties of self-adhesive versus conventional resin cements. Methods: Specimens of a conventional (RelyX ARC) and 3 self-adhesive (RelyX U200, Maxcem Elite, Bifix SE) types of resin cements were prepared. The Knoop test was used to assess the microhardness, using a Microhardness Tester FM 700. For the diametral tensile strength test, a tensile strength was applied at a speed of 0.6 mm/minute. A universal testing machine was used for the analysis of compressive strength and a thermo-controlled oscillating rheometer was used for the Rheology test. One-way ANOVA and Tukey’s test (α=0.05) were used for data analysis. Results: According to microhardness analysis, all the cements were statistically similar (p>0.05), except for Maxcem that presented lower hardness compared with the other cements in relation to the top surface (p<0.05). In the diametral tensile strength test, Relyx U200 and RelyX ARC cements were statistically similar (p>0.05), presented higher value when compared to the Maxcem and Bifix cements (p<0.05). The compressive strength of RelyX ARC and Maxcem Elite cements was statistically higher than RelyX U200 and Bifix cements (p<0.05). Regarding the rheology test, Maxcem Elite and RelyX ARC cements showed a high modulus of elasticity. Conclusions: The self-adhesive cements presented poorer mechanical properties than conventional resin cement. Chemical structure and types of monomers employed interfere directly in the mechanical properties of resin cements.
Marginal staining of ultra-thin ceramic veneers
Authors: Zago Renata Ragagnin , Swarowsky Luciana Abitante , Teixeira Gabriela Simões , Marquezan Marcela , Susin Alexandre Henrique , Durand Letícia Brandão
Published: September 2020

The pigmentation of the resin cement at the tooth/ceramic interface compromises the esthetic and longevity of ultra-thin ceramic veneers. Aim: The aim of this study was to evaluate marginal staining of ultra-thin ceramic veneers cemented to intact enamel (non-prepared) and prepared enamel. Methods: Thirty-two (32) permanent central incisors were selected and randomly divided into two groups: intact enamel (IE) and prepared enamel (PE). The ceramic veneers of PE group were bonded to the prepared enamel and the ceramic veneers of IE group were cemented directly onto the intact enamel, with no preparation. Both preparation and cementation were standardized and performed by a single operator. Each group was subdivided into two subgroups (n = 8) with different immersion media - coffee and water. After an immersion period of 10 days, stereomicroscope images were made at 20X magnification of the mesial, distal, cervical and incisal surface of each specimen. Three blinded, trained and calibrated examiners evaluated the images of the resin cement interface of each surface. The data were subjected to Kruskal‑Wallis and Mann‑Whitney statistical analysis. Immersion media and enamel preparation influenced the marginal staining of the tooth/ceramic interface. Results: When immersed in coffee, prepared interfaces presented greater marginal staining than unprepared interfaces. When immersed in water, there was no statistically significant difference between the groups. Conclusion: The cementation of ultra-thin ceramic veneers onto intact enamel is associated with less marginal staining and, consequently, improved esthetics.
África e os africanos em textos e imagens da Revista Eu Sei Tudo (1917-1958)
Authors: Guimarães Ana Carolina de Carvalho , Salvadori Maria Angela Borges
Published: September 2020

O magazine ilustrado Eu Sei Tudo foi publicado no Brasil entre 1917 e 1958. Sua origem, entretanto, é francesa e parte significativa de seu conteúdo pertencia também àquela versão. Neste artigo, tomando como fontes históricas figuras e textos presentes na revista brasileira e adotando como referencial teórico os conceitos de representação e imaginário social, investigamos a produção e a circulação entre mundos de imagens relativas à África e aos africanos, inquirindo sobre seus significados. Nossa hipótese é a de que a Eu Sei Tudo promoveu a difusão de estereótipos e preconceitos raciais a partir de uma matriz europeia ligada ao contexto do imperialismo, reproduzida em várias de suas páginas, apesar dos cenários sociais radicalmente diferentes. Tais imagens e textos, expostos a partir de um discurso sobre a alteridade, repetiam no Brasil os supostos antagonismos entre modernidade e atraso, primitivismo e progresso, civilização e barbárie.
Professor cosmopolita
Authors: Pereira Pablo , Heinzle Marcia Regina Selpa
Published: September 2020

Esta pesquisa qualitativa, orientada pelo método compreensivo weberiano, objetivou compreender o papel do professor no processo de internacionalização nos Programas de Pós-Graduação stricto sensu de uma instituição pública municipal de ensino superior. Para isso, buscamos caracterizar as ações dos professores, bem como apreender suas razões, no processo de internacionalização. Em relação ao marco teórico, os estudos de Knight, Sanderson, entre outros, sustentaram a análise do material empírico. Quanto aos instrumentos para geração de dados e às fontes de pesquisa, realizamos análise de documentos de arquivos públicos e entrevista semiestruturada com quatro professores vinculados à instituição. Os resultados indicaram, na atuação dos professores, a produção intelectual, o intercâmbio acadêmico-científico, a gestão intercultural e a internacionalização do currículo, como tipos de ação racional em finalidade e em valores. À vista disso, compreendemos que o papel do professor da pós-graduação se configura por seu protagonismo cosmopolita no processo de internacionalização intrainstitucional.
Internationalizations in two loci of enunciation
Authors: Finardi Kyria Rebeca , Sembiante Sabrina , Amorim Gabriel , Veronez Thiago
Published: September 2020

This paper confronts epistemological myopia to decolonize academic knowledge by exposing scholars’ loci of enunciation to localize knowledge that are often taken as universal. In doing so, we reflect about the process of internationalization of higher education (IHE), from two different loci of enunciation--one in the Global South (UFES) and another in the Global North (FAU). Based on the claim that language policies are closely related to internationalization actions/plans, and in the description of internationalization models in terms of the Traditional International Cooperation (TIC) model, characterized by competitive relations, and the Horizontal International Cooperation (HIC) model based on solidarity and international awareness, we analyze language policies and international cooperation agreements at UFES and at FAU as a window for reflecting about the internationalization processes in these institutions. The analysis of language policies and international agreements at UFES suggests a reactive and colonial nature of the internationalization process there, expressed in the number of agreements with institutions from the Global North and in language policies and actions that privilege the use of English.  The analysis of international cooperation agreements and language policies at FAU suggest that internationalization strategies are largely designed based on the university’s privileged position as an English-speaking institution located in the Global North. Taken together, overall results of the study suggest that despite the pitfalls, the partnership between UFES and FAU shows potential to forge inroads for more horizontal internationalization models/relationships thus moving form a TIC to a HIC model of internationalization.
Desenvolvimentos da internacionalização da educação superior no Brasil
Authors: Knobel Marcelo , Lima Manolita Correia , Leal Fernanda Geremias , Prolo Ivor
Published: September 2020

O objetivo deste artigo é analisar os desenvolvimentos recentes da internacionalização da educação superior brasileira, a partir nos principais programas governamentais direcionados ao fomento do processo no período de 2011 a 2018. Especificamente, três programas são abordados, com maior ênfase no terceiro: o “Ciência sem Fronteiras (CsF)”, vigente de 2011 a 2015; o “Idiomas sem Fronteiras (IsF)”, iniciado em 2012; e o “Programa Institucional de Internacionalização (Capes-PrInt)”, iniciado em 2018. O texto se desenvolve com base na combinação de recursos bibliográficos e documentais e se sustenta nos seguintes argumentos: 1. No Brasil, o entendimento da internacionalização da educação superior tem evoluído de um sinônimo de mobilidade acadêmica internacional, centrada nos indivíduos, para uma concepção mais abrangente do fenômeno, focada na transformação da instituição universitária; 2. A despeito dos novos direcionamentos, no período em evidência a internacionalização permanece majoritariamente atrelada aos interesses desenvolvimentistas do Estado; 3. Tais direcionamentos sinalizam que esse processo se consolida no país de forma hegemônica, em consonância com a perspectiva mundialmente dominante. Após a análise dos três programas, conclui-se o artigo com reflexões suscitadas pela perspectiva de internacionalização recentemente proposta pelo governo federal às Instituições Federais de Ensino Superior (IFES) por meio do ‘Future-se’, com destaque para três aspectos: o comprometimento da autonomia administrativa da universidade, a interferência de órgãos estranhos à vida acadêmica da instituição, e a pressão pelo autofinanciamento decorrente da diversificação das fontes de financiamento.
Os limites de um currículo eurobrancocêntrico e as expectativas de uma formação crítica e antirracista em um curso de licenciatura em História
Authors: Da Silva José Bonifácio Alves
Published: September 2020

Discuto a formação pretendida por um curso de licenciatura em História pertencente a uma universidade pública do estado do Paraná, Brasil. Essa formação está pautada em uma perspectiva crítica da história e da educação, mas também no antirracismo. Apresento a tensão entre as expectativas de formar docentes críticos antirracistas e o eurobrancocentrismo no currículo dessa licenciatura por meio da análise de registros feitos, inspirados na etnografia, de aulas do curso assistidas, do projeto pedagógico do curso e de entrevistas feitas com estudantes e professores do curso. No currículo da licenciatura em História participante da pesquisa, de modo ambivalente, coexistem críticas e conivências com o eurobrancocentrismo. Embora a Europa e o branco, enquanto referenciais, sejam os eixos principais em torno dos quais o currículo do curso ainda se movimenta, também acontecem eventuais iniciativas de mostrar os protagonismos históricos dos indígenas e dos negros que servem para o combate às representações racistas.
Effect of Ethanol Extract of Date Palm Fruit (Phoenix dactylifera. L) on Spermatozoa Concentration of BALB/c Mice (Mus Musculus) Exposed to 2-Methoxyethanol
Authors: Yassin Tita Rudini , Yaudiwati Rina , I’tishom Reny
Published: September 2020

Antioxidants are important compounds for the human body because they function to capture free radicals causing degenerative diseases. Flavonoid and phenolic compounds in dates have antioxidant activity that can inhibit the increase in lipid peroxide and protein oxide. This study aims to prove the increase in the concentration of mice (Mus musculus) spermatozoa given ethanol extract dates and exposed to 2-methoxyethanol. Experimental animals used 35 mice (Mus musculus), divided into 5 groups (7 mice per group). The negative control group (K-) was the control group without administration of 2-methoxyethanol and date ethanol extract, the positive control group (K+) was given 200 mg/kg 2-methoxyethanol + CMC 0.5%, the treatment group 1 (P1) was given 200 mg/kg BW 2-methoxyethanol + 3.5 mg/gBW of ethanol extract dates, treatment group 2 (P2) were given 200 mg/kg BW 2-methoxyethanol + 7 mg/gBW of date palm ethanol extract, and treatment group 3 (P3) were given 200 mg/kg 2-methoxyethanol + 10.5 mg/gBW of ethanol extract dates. The results showed there were significant differences in spermatozoa concentrations between the positive control group (K+) and the negative control group (K-), treatment group 1 (P1) and treatment groups 2 and 3. mice (Mus musculus) exposed to 2-methoxyethanol.
Impact of Stone Size, Location, and Stone Composition on the Efficacy of Extracorporeal Shock Wave Lithotripsy for Residual Stone after Percutaneous Nephrolithotomy
Authors: Sawal Zuhri , Soebadi Doddy M
Published: September 2020

This study aimed to determine the impact of stone size, location and stone composition the efficacy of extracorporeal shock wave lithotripsy (ESWL) in the management of residual stone after percutaneous nephrolithotomy (PCNL). The design of this study was a retrospective that conducted between January 2012 until December 2016. The population in this study were all patients with residual stones post PCNL. Exclusion criteria were patients with multiple stones and patients with a history of previous treatment for residual stones such as nephroscopy, flexible ureterorenoscopy, ESWL or medical therapy). The variables studied in this study were stone size, stone location, and stone composition. Before ESWL was carried out, all patients underwent Kidney Ureter Bladder (KUB). After ESWL, all patients underwent ultrasonography (USG) and KUB to determine the stone clearance status. The sample of this study was 125 patients. The overall stone-free rate (SFR) of ESWL in managing post-PCNL residual stones is 72%. SFR based on stone size variable are 73.7% and 71.3% respectively for stones with a size = 5 mm and >5 mm (p = 0.78). SFR based on stone location variable was 67.1%, 75.8%, and 81.8% respectively for the residual stone located at the upper pole, middle pole and lower pole. There are no significant differences in the entire variable. This study concludes that ESWL can be used as effective additional management to treat post-PCNL residual stones with satisfactory SFR.
Effect of Adaptive Exercise on Body Temperature in Children with Motoric Disorder
Authors: Mulyadi Soffil Yudha , Rejeki Purwo Sri , Tinduh Darmayanti , Sari Gadis Meinar , Prasetya Rizka Eka
Published: September 2020

Motoric disorder in child increased every year, especially cerebral palsy. Children with motoric disorder which is majority experiencing long immobilization results in their general condition declining. One of this declining appears on body temperature in child, even lead to hypothermia. A simple exercise which applicatively performed at home can be a simple solution to maintain general condition, especially body temperature. The purpose of this study was to determine effect of adaptive exercise on body temperature change in children with motoric disorder. This study was an experimental study of one group pre and posttest. A total of 31 children (11 girls and 20 boys) aged 2-10 years old performed adaptive exercise consist of warming up 5 minutes, core movement 25 minutes, cooling down 5 minutes. Data were analyzed by paired T test. Body temperature in pretest was 36.12 ± 0.53oC, and body temperature in posttest was 36.63 ± 0.6oC, with p = 0.00. Adaptive exercise can increase body temperature but still in normal range.
Kombinasi Ekstender Larutan Sari Kurma (Phoenix Dactylifera) dan Ringer Laktat pada Kualitas Spermatozoa Beberapa Ikan Air Tawar
Authors: Fariedah Fani , Sri Widodo Maheno
Published: September 2020

Penelitian ini bertujuan untuk mengetahui pengaruh kombinasi larutan ekstender kurma dan ringer laktat terhadap kualitas spermatozoa beberapa ikan air tawar dalam proses pengawetan spermatozoa. Proses pengawetan sperma tergantung pada nutrisi yang disediakan oleh bahan ekstender. Ringer laktat telah digunakan sebagai ekstender dalam proses pengawetan sperma yang berguna sebagai penyedia energi. Energi lain dapat diperoleh dari bahan yang mengandung fruktosa atau glukosa. Sari kurma merupakan salah satu bahan yang memiliki kandungan fruktosa dan glukosa yang diharapkan dapat membantu memberikan energi bagi sperma selama proses pengawetan sperma. Penelitian ini melakukan percobaan pengawetan sperma dari beberapa ikan air tawar ikan mas (Carrasius auratus), ikan lele siam (Pangasius hypopthalmus), dan Koi (Cyprinus carpio) menggunakan extender yang dibuat dalam kombinasi dari ringer laktat dan larutan sari kurma. Penelitian ini menggunakan berbagai konsentrasi ekstrak kurma yaitu 0,5%, 1%, 2,5%, 2% menggunakan desain rancangan acak kelompok dengan ikan sebagai kelompok. Hasil penelitian menunjukkan bahwa rata-rata motilitas ikan patin mencapai nilai tertinggi (52,00%) sedangkan rata-rata laju fertilisasi tertinggi terjadi pada spermatozoa ikan mas dengan nilai 97,068%. Larutan sari kurma mampu memberikan nutrisi pada spermatozoa selama proses pengawetan karena kurma mengandung fruktosa dan glukosa sehingga spermatozoa yang diawetkan tetap dapat membuahi secara normal.
Perbaikan Kualitas Hidup pada Pasien Solitary Fibrous Tumor Mediastinum: Perspektif Kemoterapi Paliatif
Authors: Putra Aryo Dirgantara , Koesoemoprodjo Winarinani
Published: September 2020

Background: Mediastinal solitary fibrous tumor (SFT) is a rare spindle cell neoplasm. Approximately 1 to 8% of these intrathoracic tumors have been reported to occur in the mediastinum. The chief complaints of mediastinal SFT are cough, shortness of breath or chest pain, or may occur as asymptomatic incidental mass. The treatment of choice for SFT is extensive surgical resection. However, when the tumor cannot be removed surgically or when metastases occur, chemotherapy and or radiotherapy can be proposed as palliative treatments. Case: A 19-year-old man with chief complaint of left chest pain and referred to his left back. The complaint is accompanied by cough without sputum and hoarseness. In thoracic CT scan with contrast, we found giant cystic mass suspect malignancy around 17x12x18 cm in left hemithorax, a minimal pericardial effusion, and left pleural effusion. There were positive tumor cell cytoplasm results in vimentin, negative tumor cell cytoplasm in CK, positive tumor cell membrane in CD99, cytoplasm of focal positive tumor cells in EMA, and negative tumor cells in CD34 which supported a solitary fibrous tumor in the immunohistochemical staining analysis. Doxorubicin-Ifosfamide regimen was the choice of chemotherapy palliative treatment in the case report. In the CT scan evaluation of thorax with contrast, we found stable disease (RECIST criteria) with improve quality of life (QOL) according to EQ-5D-3L, 11111 indicated no problems in 5 dimensions, such as mobility, self-care, usual activities, pain or discomfort, and anxiety or depression. Conclusion: Mediastinal SFT is a rare spindle cell neoplasm, and the diagnosis requires pathological and immunohistochemical staining analysis. Doxorubicin-Ifosfamide regimen can be proposed as a palliative chemotherapy regimen, which has been shown to improve QOL patients in Mediastinal SFT. EQ-5D is a simple tool that can be used to measure QOL such as mobility, self-care, usual activities, pain or discomfort, and anxiety or depression.
Penggunaan Extrafine Beclometason Diproprionat/Formoterol Fumarat pada PPOK
Authors: Syarifah Sakinatus , Amin Muhammad
Published: September 2020

Chronic obstructive pulmonary disease (COPD) is a condition characterised by poorly reversible airflow limitation that is generally progressive and causes serious disability. Exacerbations and co-morbidities contribute to the overall severity in individual patients. A fixed-dose inhaled corticosteroid/long-acting β2-agonist (ICS/LABA) combination of extrafine beclometasone dipropionate and formoterol fumarate (BDP/FF) has been recently approved for use in COPD. Small airway inflammation and remodelling are cardinal features of COPD; therefore, the ability of this extrafine formulation to reach the small, as well as the large, airways is likely to be therapeutically important by enabling treatment of inflammatory processes in the whole bronchial tree. The clinical development of extrafine BDP/FF has demonstrated significant benefits over extrafine FF in terms of lung function improvement and reduction of the exacerbation rate, thus supporting the beneficial effect of an ICS combined to a LABA in COPD patients. Head-to-head comparison studies versus other ICS/LABA combinations have shown that extrafine formulation enables clinical benefits to be achieved with a lower dose of ICS. Extrafine BDP/FF showed lung function and dyspneea improvements comparable to other ICS/LABAs, and a significantly faster onset of action was observed when compared with a salmeterol-containing fixed-dose combination.
Sustainable synthesis of omega-3 fatty acid ethyl esters from monkfish liver oil
Authors: Aguilera-Oviedo Johanna , Yara-Varón Edinson , Torres Mercè , Canela-Garayoa Ramon , Balcells Mercè
Published: September 2020

The search for economical and sustainable sources of PUFAs within the framework of the circular economy is encouraged by their proven beneficial effects on health. The extraction of monkfish liver oil (MLO) for the synthesis of omega-3 ethyl esters was performed evaluating two blending systems and four green solvents. Moreover, the potential solubility of the MLO in green solvents was studied using the predictive simulation software COSMO-RS. The production of the ethyl esters was performed by one or two step reactions. Novozym 435, two resting cells (Aspergillus flavus and Rhizopus oryzae) obtained in our laboratory and mix of them were used as biocatalysts in a solvent-free system. The yields for Novozym 435, R. oryzae and A. flavus in the one-step esterification were 63%, 61% and 46%, respectively. The hydrolysis step in the two-step reaction led to 83%, 88% and 93% of free fatty acids (FFA) for Novozym 435, R. oryzae and A. flavus respectively. However, Novozym 435 showed the highest yield in the esterification step (85%) followed by R. oryzae (65%) and A. flavus (41%). Moreover, selectivity in front of polyunsaturated fatty acids of R. oryzae lipase was evidenced, since it did slightly esterified docosahexaenoic acid (DHA) in all the esterification reactions tested.
How the Lagged and Accumulated Effects of Stress, Coping and Task Affect Mood and Fatigue during Nurse’s Shifts
Authors: Martínez-Zaragoza Fermín , Fernández-Castro Jordi , Benavides-Gil Gemma , García-Sierra Rosa
Published: September 2020

Nurses experience significant stress and emotional exhaustion, leading to burnout and fatigue. This study assessed how the nurses’ mood and fatigue evolves during their shifts, and the lagged and accumulated factors that influence these phenomena. A two-level design with repeated measures was applied to a sample of 113 nurses, performing an ecological momentary assessment of different parameters and multilevel longitudinal two-level modelling of the data. Accordingly, mood appeared to be explained by effort, by the negative lagged effect of reward and by accumulated effort, each following a quadratic trend, and it was influenced by previously executing a direct care task. By contrast, fatigue was explained by the current and lagged effect of effort, by the lagged effect of reward and by accumulated effort, again following quadratic trends. Fatigue was also associated with direct care, and the prior effect of documentation and communication tasks. Mood was also explained by problem-focused and emotion-focused coping strategies, indicative of negative mood, and by support-seeking and refusal coping strategies. Hence, mood and fatigue do not depend on a single factor like workload but rather, on the evolution and distribution of tasks, as well as on the stress during a shift and how it is handled.
Kiai, Transformasi Pesantren dan Pencarian Model Gender Mainstreaming di Pesantren Subulussalam Tulungagung
Authors: Abidin Ahmad Zainal , Ahmadi Imam , Imamah Fardan Mahmudatul
Published: September 2020

Artikel ini berusaha mengungkap bagaimana peran kiai dapat dimaksimalkan untuk melakukan transformasi pesantren dengan menitikberatkan pada aspek keadilan gender di lingkungan pesantren. Teknik pengumpulan data melalui observasi, wawancara dan dokumentasi. Dengan metode deskriptif-partisipatoris, tulisan ini menunjukkan peran kiai sebagai sumber kebijakan yang memiliki implikasi langsung terhadap proses pengarusutamaan gender. Hal ini bertolakbelakang dengan pemahaman umum yang merujuk pada pandangan Geertz dimana Kiai sebagai penjaga tradisi dan konservatisme beragama, sulit untuk menerima perubahan. Namun saat ini, ditemukan berbagai upaya yang membuktikan argumentasi Dhofir terhadap Geertz, bahwa kiai dapat menjadi pusat inovasi di lingkungan pesantren yang secara signifikan. Melalui perencanaan dan pembiasaan, seluruh aktivitas yang melibatkan santri putra maupun putri di pesantren Subulussalam Tulungagung diupayakan untuk menunjukkan model gender mainstreaming, dimana keduanya memiliki hak dan kewajiban yang sama dalam menjalankan program pondok pesantren. Kerja sama tersebut untuk mengajarkan dengan santri bahwa kedudukan putra dan putri adalah setara baik dalam ruang publik maupun ruang domestik.
НОВАЯ КОРОНАВИРУСНАЯ ИНФЕКЦИЯ У ДЕТЕЙ В РОССИЙСКОЙ ФЕДЕРАЦИИ
Authors: Горелов Александр , Николаева Светлана , Акимкин Василий
Published: September 2020

В последние месяцы человечество столкнулось c вызванной новым штаммом коронавируса человека (SARS-CoV-2) инфекцией COVID-19, повсеместное распространение которой способствует развитию этой болезни не только у взрослых, но и у детей.

Цель: определить клинико-эпидемиологические особенности новой коронавирусной инфекции COVID-19 у детей.

Результаты. За 1 полугодие 2020 года в Российской Федерации было зарегистрировано 47712 случаев COVID-19 у детей, что составило 8,4% от общего числа заболевших. Болеют дети всех возрастов, при этом мальчики – несколько больше, чем девочки (52,2% против 47,8%, р>0,05). Среди госпитализированных пациентов преобладали дети раннего возраста – до 3 лет. У подавляющего большинства детей новая коронавирусная инфекция протекала в легкой форме (49,9%), у 32,3% пациентов подтверждено бессимптомное течение. Тяжелую форму болезни регистрировали крайне редко – в 0,2% всех случаев, что существенно ниже, чем у взрослых.

Заключение. Течение новой коронавирусной инфекции в детской популяции протекает, в целом, благоприятно.
The Biomaterials of Total Shoulder Arthroplasty
Authors: Mehta Nabil , Hall Deborah J. , Pourzal Robin , Garrigues Grant E.
Published: September 2020

» The materials that are used in total shoulder arthroplasty (TSA) implants have been carefully chosen in an attempt to minimize hardware-related complications.

» The 2 main metal alloys used in TSA implants are Ti-6Al-4V (titanium-aluminum-vanadium) and CoCrMo (cobalt-chromium-molybdenum). Ti alloys are softer than CoCr alloys, making them less wear-resistant and more susceptible to damage, but they have improved osseointegration and osteoconduction properties.

» Although controversial, metal allergy may be a concern in patients undergoing TSA and may lead to local tissue reaction and aseptic loosening.

» Numerous modifications to polyethylene, including cross-linking, minimizing oxidation, and vitamin E impregnation, have been developed to minimize wear and reduce complications.

» Alternative bearing surfaces such as ceramic and pyrolytic carbon, which have strong track records in other fields, represent promising possibilities to enhance the strength and the durability of TSA prostheses.
La “Londiga” de Burgos en el Setecientos
Authors: Sanz de la Higuera Francisco José Alejandro
Published: September 2020

Resumen: La alhóndiga de Burgos, edificada en el siglo XVI, precisó, a lo largo del XVIII, de varios reparos y actuaciones constructivas, de mayor o menor envergadura, que la hicieron totalmente operativa. El objetivo era que no se impidieran sus quehaceres esenciales. Como ocurriera con otros muchos inmuebles públicos, y privados, en el Burgos del Setecientos, se impuso la necesidad de efectuar un “Hermoseamiento” de sus edificios, calles y plazas, en una centuria, la de las Luces, que ilustraba las mentes a través de los ojos. Los distintos mayordomos del pósito y “lóndiga” exigieron del Concejo su constante revisión y mantenimiento, en aras de no sufrir cortapisas ni obstáculos en el cometido de comprar, vigilar y prestar trigo a los labradores necesitados de granos para sus sementeras y alimento. Las adversidades meteorológicas y climáticas castigaban los campos de cultivo y los edificios de las ciudades pre-industriales. Palabras clave: Alhóndiga, obras, mayordomo, Burgos, siglo XVIII.   THE "LONDIGA" IN BURGOS IN THE 18TH CENTURY Abstract: The alhóndiga in Burgos, built in the sixteenth century, required, throughout the eighteenth, several repairs and constructive actions, of greater or lesser importance, which made it fully operational. The goal was not to prevent their essential tasks. As it happened with many other public and private buildings, in Burgos in the seventeenth, the need to make an “embellishment”of its buildings, streets and squares, in a century, the Age of Enlightenment, which illustrated the minds through the eyes. The different “mayordomos of the pósito” and "lóndiga" demanded from the Council its constant revision and maintenance, so as not to undergo limitations or obstacles in the task of buying, monitoring and lending wheat to the farmers who needed grains for their seeding and food. The meteorological and climatic adversities punished the farming lands and the buildings of the pre-industrial cities. Keywords: Alhóndiga, works, mayordomo, Burgos, 18th century
Fernando de Torres y Portugal, conde de Villardompardo, y su intento frustrado de compra del lugar de Jamilena de la encomienda calatrava de Martos (1561)
Authors: Illana López Francisco Javier
Published: September 2020

Resumen: Este trabajo analiza la figura de Fernando de Torres y Portugal, I Conde de Villardompardo, atendiendo a su faceta señorial y nobiliaria, y profundizando en un caso concreto de la compra de jurisdicción: el lugar de Jamilena. Para ello se parte de fuentes localizadas en el Archivo Histórico Nacional y Archivo General de Simancas, con las que se pretende atender a un capítulo desconocido de la vida y obra de este aristócrata giennense de la segunda mitad del siglo XVI.Palabras clave: Fernando de Torres y Portugal, señorío, ventas jurisdiccionales, Villardompardo, Jamilena. Abstract: The aim of this paper is to study the figure of Fernando de Torres y Portugal, I Count of Villardompardo in the 16th Century. We pay attention to his noble image and analyze a specific event in his life: a jurisdiction sale in the village of Jamilena. We use documentary sources located in the National Historical Archive and General Archive of Simancas, in order to explain an unknown event in the life of this Spanish aristocrat.Keywords: Fernando de Torres y Portugal, estate, sales of jurisdictions, Villardompardo, Jamilena.
Castillos, palacios y un puente sobre el Genil: Proyección patrimonial del ascenso social. El caso de los Bernuy
Authors: Rivas de la Torre José Antonio
Published: September 2020

Durante la Edad Moderna asistimos a un proceso de renovación del estamento nobiliario, por el cual nuevos linajes, muchos de ellos de origen converso, se van a incorporar a la nobleza. Este fenómeno de promoción social y ennoblecimiento tiene un claro reflejo en el patrimonio, convertido este en un medio a través del cual expresar el poder, la riqueza y el nuevo estatus social del linaje. En este caso pretendemos estudiar una de estas familias, los Bernuy, un linaje que durante los siglos de la Modernidad experimentará un impresionante ascenso social que les llevará desde el patriciado urbano burgalés hasta la nobleza titulada, atendiendo a como este proceso se ve reflejado en el patrimonio artístico vinculado al linaje. Pretendemos con esto evidenciar la importancia del colectivo judeoconverso en la promoción artística durante la Edad Moderna y la necesidad de su estudio.
A TRADIÇÃO FÁUSTICA E A TRAGÉDIA SUBJETIVA NO FAUSTO DE FERNANDO PESSOA
Authors: Santos Rafael Rocca dos
Published: September 2020

A tradição fáustica, como mito do individualismo moderno, é um dos temas mais profícuos da literatura ocidental. Iniciada no século XVI, a temática de Fausto deu origem a centenas de narrativas e peças teatrais que continuam a ser escritas e encenadas. Tendo em vista a abrangência e a relevância da temática, este artigo traça um panorama histórico dos principais textos sobre Fausto desde o século XVI até o romantismo, construindo o que aqui se denomina tradição fáustica. Além da introdução da temática fáustica em Portugal, analisam-se as modificações operadas na tradição naquele que pode ser lido como o Fausto moderno por excelência, o Fausto de Fernando Pessoa, designado pelo autor como sua “tragédia subjetiva”.
Anti-inflammatory Effect of Ampelocissus Indica (L.) Planch (Chembravalli) in Wistar Rats
Authors: S Nithya V , C Indulekha V , Antony Helen
Published: September 2020

The authors have withdrawn this preprint due to author disagreement.
Transcription Factor KLF4: A Potential Biomarker of Non-small Cell Lung Cancertranscription Factor KLF4: A Potential Biomarker of Non-small Cell Lung Cancer
Authors: Zhang Jixin , Wu Yanping , Lin Lianjun , Liu Xinmin
Published: September 2020

Background Krüppel-like factor 4 (KLF4) is a member of the zinc finger transcription factor family and plays an important role in cell proliferation, differentiation, apoptosis, embryonic development, organ formation, and tumor invasion. There is little research on the clinicopathological characteristics and KLF4 expression in non-small cell lung cancer (NSCLC). Methods We conducted a retrospective study to further explore the correlation between KLF4 expression and clinicopathological features of NSCLC by immunohistochemical staining. Results This study included 81 males (52.3%), 74 females (47.7%), and 101 (65.2%) ages <65, 54 (34.8%) ages ≥65 years. A total number of 127 cases (81.9%) were adenocarcinoma, 26 cases (16.8%) were squamous cell carcinoma, and 2 cases (1.3%) were large cell carcinoma. There were 140 patients (89.7%) in T1-T2 phase and 15 patients in T3-T4 phase; 130 patients (83.9%) in N0 phase and 25 patients (16.1%) in N1-N3 phase. There were no distant metastases in 154 patients (99.4%), and only 1 patient (0.6%) was in M1 phase. In terms of clinical stage, 142 patients (91.6%) in stage I-II and 13 patients (8.4%) in stage III-IV. The number of patients with smoking history was 40 (25.8%). KLF4 expression in NSCLC tissues was significantly decreased compared with normal lung tissues (P<0.001); KLF4 expression in adenocarcinoma was lower than that in normal lung tissues (P<0.001), while there was no significant difference in quamous cell carcinoma (P=0.314). Higher KLF4 expression was significantly associated with clinicopathological features of NSCLC such as squamous cell carcinoma (P<0.001), later T stage (T3-T4 stage) (P=0.013), lymph node metastasis (P=0.011), later clinical stage (III-IV stage) (P=0.001). KLF4 expression was not associated with age (P=0.082); there was no significant difference in KLF4 expression between male and female patients with adenocarcinoma (P=0.709). It was also found that KLF4 was positively correlated with Ki-67 expression in patients with adenocarcinoma (r=0.272, P=0.002). Conclusions Aboval all, the tumor suppressor gene KLF4 might become a potential biomarker and a new therapeutic target for lung cancer patients.