bluuebunny/crossref_metadata_2025 huggingface dataset:
Eosinophil-specific deletion of IκBα in mice reveals a critical role of NF-κB–induced Bcl-xL for inhibition of apoptosis
Authors: Schwartz Christian , Willebrand Ralf , Huber Silke , Rupec Rudolf A. , Wu Davina , Locksley Richard , Voehringer David
Published: April 2015

Key Points

IL-3, IL-5, and GM-CSF promote eosinophil survival by NF-κB–induced upregulation of Bcl-xL, which can be blocked by specific inhibitors. Specific and constitutive deletion of the inhibitor of NF-κB (IκBα) in eosinophils in vivo reduced apoptosis during helminth infection.
MEF2 Cooperates With Forskolin/cAMP and GATA4 to Regulate Star Gene Expression in Mouse MA-10 Leydig Cells
Authors: Daems Caroline , Di-Luoffo Mickaël , Paradis Élise , Tremblay Jacques J.
Published: April 2015

In Leydig cells, steroidogenic acute regulatory protein (STAR) participates in cholesterol shuttling from the outer to the inner mitochondrial membrane, the rate-limiting step in steroidogenesis. Steroid hormone biosynthesis and steroidogenic gene expression are regulated by LH, which activates various signaling pathways and transcription factors, including cAMP/Ca2+/CAMK (Ca2+/calmodulin-dependent kinase)–myocyte enhancer factor 2 (MEF2). The 4 MEF2 transcription factors are essential regulators of cell differentiation and organogenesis in numerous tissues. Recently, MEF2 was identified in Sertoli and Leydig cells of the testis. Here, we report that MEF2 regulates steroidogenesis in mouse MA-10 Leydig cells by acting on the Star gene. In MA-10 cells depleted of MEF2 using siRNAs (small interfering RNAs), STAR protein levels, Star mRNA levels, and promoter activity were significantly decreased. On its own, MEF2 did not activate the mouse Star promoter but was found to cooperate with forskolin/cAMP. By chromatin immunoprecipitation and DNA precipitation assays, we confirmed MEF2 binding to a consensus element located at −232 bp of the Star promoter. Mutation or deletion of the MEF2 element reduced but did not abrogate the MEF2/cAMP cooperation, indicating that MEF2 cooperates with other DNA-bound transcription factor(s). We identified GATA4 (GATA binding protein 4) as a partner for MEF2 in Leydig cells, because mutation of the GATA element abrogated the MEF2/cAMP cooperation on a reporter lacking a MEF2 element. MEF2 and GATA4 interact as revealed by coimmunoprecipitation, and MEF2 and GATA4 transcriptionally cooperate on the Star promoter. Altogether, our results define MEF2 as a novel regulator of steroidogenesis and Star transcription in Leydig cells and identify GATA4 as a key partner for MEF2-mediated action.
oskar RNA plays multiple noncoding roles to support oogenesis and maintain integrity of the germline/soma distinction
Authors: Kanke Matt , Jambor Helena , Reich John , Marches Brittany , Gstir Ronald , Ryu Young Hee , Ephrussi Anne , Macdonald Paul M.
Published: April 2015

The Drosophila oskar (osk) mRNA is unusual in that it has both coding and noncoding functions. As an mRNA, osk encodes a protein required for embryonic patterning and germ cell formation. Independent of that function, the absence of osk mRNA disrupts formation of the karyosome and blocks progression through oogenesis. Here we show that loss of osk mRNA also affects the distribution of regulatory proteins, relaxing their association with large RNPs within the germline, and allowing them to accumulate in the somatic follicle cells. This and other noncoding functions of the osk mRNA are mediated by multiple sequence elements with distinct roles. One role, provided by numerous binding sites in two distinct regions of the osk 3′ UTR, is to sequester the translational regulator Bruno (Bru), which itself controls translation of osk mRNA. This defines a novel regulatory circuit, with Bru restricting the activity of osk, and osk in turn restricting the activity of Bru. Other functional elements, which do not bind Bru and are positioned close to the 3′ end of the RNA, act in the oocyte and are essential. Despite the different roles played by the different types of elements contributing to RNA function, mutation of any leads to accumulation of the germline regulatory factors in the follicle cells.
Fundraising for land-based initiatives
Authors: Craven Sophie
Published: April 2015

Sophie Craven explains how schools can access funding for land-based initiatives that support teaching and learning in their school.
Tips on getting ready for the budget squeeze
Authors: Bannister Nick
Published: April 2015

There may be trouble ahead for school budgets, so what can you do to prepare your school? Nick Bannister invites Simon Oxenham of NASBM to share some advice.
Thinking outside the box
Authors: Davis John
Published: April 2015

Help your pupils to understand the properties of 3D shapes with these games and puzzles that involve exploring cubes, cuboids, prisms, cylinders and pyramids.
Program in Kodu to bring 3D worlds to life
Authors: Rachel  , Bosley Mark
Published: April 2015

The sophisticated worlds of Kodu encourage imagination, creativity and problem solving skills, while also helping children learn to code on an intuitive level.
‘There was an old man…’
Authors: Murray John
Published: April 2015

Encourage pupils to engage with the life of the nonsense poet Edward Lear in this extract taken from Hopscotch Books' The Classics, A Voyage of Discovery Year 3.
Balancing the evidence
Authors: Fernandes Sarah-Anne
Published: April 2015

Challenged by assessing pupils in maths? Subject expert Sarah-Anne Fernandes provides advice on the best ways to test and record pupils' progress.
Give them a warm
Authors: Williams Kate
Published: April 2015

Want to get your children fired up about reading and writing? An author visit is always an exciting option but it will require careful thought and advance planning.
Diagnosis of acute myocardial infarction in patients with renal insufficiency using high-sensitivity troponin T
Authors: Huang Hualan , Zhu Shuai , Wang Weiqing , Yi Hong , Du Xiangyang , Nie Xin , He Yong , Song Haolan , Miao Qiang , Wang Lanlan , Li Guixing
Published: April 2015

The objective of this study was to examine the diagnostic accuracy of high-sensitivity cardiac troponin T (hs-cTnT) for acute myocardial infarction (AMI) in patients with renal insufficiency, since this population has a high incidence of non-AMI elevations of hs-cTnT.

In this prospective study, we enrolled 2249 consecutive patients presenting with chest pain in the emergency department (ED), of whom 19.5% had an estimated glomerular filtration rate (eGFR)

Of the patients, 1108 (49.3%) were diagnosed as having AMI [321 with non-ST segment elevation myocardial infarction (NSTEMI)]. In patients whose final diagnosis was not AMI, there was a low but significant correlation between hs-cTnT and renal function [eGFR

Using a higher hs-cTnT cut-off value based on eGFR level is necessary for accurate diagnosis of AMI or NSTEMI in patients with renal insufficiency.
Biological variation of high sensitivity cardiac troponin-T in stable dialysis patients: implications for clinical practice
Authors: Fahim Magid A. , Hayen Andrew D. , Horvath Andrea R. , Dimeski Goce , Coburn Amanda , Tan Ken-Soon , Johnson David W. , Craig Jonathan C. , Campbell Scott B. , Hawley Carmel M.
Published: April 2015

Changes in high sensitivity cardiac troponin-T (hs-cTnT) concentrations may reflect either acute myocardial injury or biological variation. Distinguishing between these entities is essential to accurate diagnosis, however, the biological variation of hs-cTnT in dialysis population is currently unknown. We sought to estimate the within- and between-person coefficients of variation of hs-cTnT in stable dialysis patients, and derive the critical difference between measurements needed to exclude biological variation with 99% confidence.

Fifty-five prevalent haemo- and peritoneal-dialysis patients attending two metropolitan hospitals were assessed on 10 consecutive occasions; weekly for 5 weeks then monthly for 4 months. Assessments were conducted at the same dialysis cycle time-point and entailed hs-cTnT testing, clinical review, electrocardiography, and bioimpedance spectroscopy. Patients were excluded if they developed clinical or physiological instability.

In total 137 weekly and 114 monthly hs-cTnT measurements from 42 stable patients were analysed. Respective between- and within-person coefficients of variation were 83% and 7.9% for weekly measurements, and 79% and 12.6% for monthly measurements. Within-person variation was unaffected by dialysis modality or cardiac co-morbidity. The bidirectional 99% reference change value was –25% and +33% for weekly measurements, and –37% and +58% for monthly measurements.

The between-person variation of hs-cTnT in the dialysis population is markedly greater than within-person variation indicating that hs-cTnT testing is best applied in this population using a relative change strategy. An increase of 33% or a reduction of 25% in serial hs-cTnT concentrations measured at weekly intervals excludes change due to analytical and biological variation alone with 99% confidence.
Politics at the Precipice: Fixing Social Security in 2033
Authors: Arnold R. Douglas
Published: April 2015

Social Security will be insolvent in 2033. If nothing is done, retirees will face an immediate 23% cut in their monthly benefits. The solvency cliff and its approximate date have been known for more than two decades. This paper examines why Congress has avoided fixing Social Security when the solutions were relatively affordable and when the baby-boom generation could have helped pay its share of the costs. It also examines what solutions will become politically feasible once the solvency cliff arrives. The surprise is that raising the wage base – in short, taxing the affluent – becomes the most politically appealing fix when insolvency arrives, despite the fact that this solution has no political appeal absent a crisis. Politics at the precipice is very different from ordinary politics.
On Martha Derthick
Authors: Davies Gareth
Published: April 2015

Martha Derthick, one of the nation’s foremost scholars of federalism and public administration, died on January 12. Gareth Davies, one of her former students, reflects here on her intellectual legacy, especially as reflected in her publications, but also, more briefly, on her approach to mentoring.
Not Such a CLASS Act: America’s Long-Term Care Problem
Authors: Saldin Robert P.
Published: April 2015

Long-term care is a serious but largely unrecognized problem in the US. The CLASS Act was a new program embedded within the Affordable Care Act that was supposed to bring relief to disabled individuals and Medicaid, the primary payer for long-term care. However, the program had an unworkable design, and it was eventually abandoned by the Obama administration. CLASS’ flaws were largely the product of a policy area in which ignorance and misinformation render any effective and fiscally sound program politically unfeasible. As such, the rise and fall of the CLASS Act highlights the profound challenges facing any attempt to pass serious long-term care reform and underscores the need to raise awareness of America’s long-term care challenge.
Romeo and Juliet: The Importance of a Name
Authors: Carpi Daniela
Published: April 2015

This paper focuses on the creative or de-creative function of names in Romeo and Juliet. The dialectics between name and existence (or non-existence) is constant in the text. Let us consider “What’s in a name?” uttered by Juliet in 2.2; or the repetition of “banished” (3.2) where Romeo declares that death is in that word; or “Art thou a man?” (Friar, 3.3) that expands the meaning of man from legal to illegal entity; or also, and foremost, when Capulet threatens Juliet “I’ll ne’er acknowledge thee” (3.5), thus depriving her of legal personhood. Names can create a human being into a social being or they can deprive him of social existence. In addition to this we have Capulet’s power over Juliet which entails the problem of patria potestas: in his wish to deprive Juliet of the family name he de-creates her as a social being but also prevents her from becoming an independent adult.
Unreliable Sources for Law: Dying Declarations in Shakespeare’s King John, Othello & King Lear
Authors: J. Majeske Andrew
Published: April 2015

This essay discusses the right of confrontation generally by contrasting its fundamental import to Anglo-American legal systems with its more recent rise in significance in Continental European ones, before focusing narrowly upon a particular exception to the right of confrontation called the dying declaration. This essay analyzes a highly unusual intersection of literature and law in which a renowned legal scholar errs in relying upon a passage in imaginative literature as the primary support for his argument for how the dying declaration exception to the hearsay rule should be interpreted and applied.
Voice, Authority and the Law in Peter Carey’s True History of the Kelly Gang
Authors: Antor Heinz
Published: April 2015

In
Impact of estrogen and progesterone receptor expression on the clinical and molecular features of papillary thyroid cancer
Authors: Vannucchi Guia , De Leo Simone , Perrino Michela , Rossi Stefania , Tosi Delfina , Cirello Valentina , Colombo Carla , Bulfamante Gaetano , Vicentini Leonardo , Fugazzola Laura
Published: April 2015

Background

Thyroid cancer is highly prevalent in women during the fertile age, which suggests a possible impact of hormonal and reproductive factors.

Methods

We studied the expression of estrogen receptor α (ERα or ESR1) and progesterone receptor (PR or PGR) in 182 female and male patients with papillary thyroid cancer and correlated it to clinical and molecular features.

Results

ERα and PR expression was found in 66.5 and 75.8% of patients respectively and was significantly correlated with larger tumor size and with a non-incidental diagnosis. Moreover, a trend toward a higher prevalence of local metastases was observed in ER- and PR-expressing tumors, which possibly indicates a more aggressive behavior. Interestingly, the occurrence of the ‘receptor conversion’ phenomenon, which has already been reported to have a negative prognostic effect in breast cancer, was demonstrated for the first time in thyroid tumors. Indeed, almost all of the ERα-positive primary tumors analyzed had ERα-negative metastatic lymph nodes. At the genetic analyses,BRAFV600Emutation was detected in 23.2% of the tumors and had a higher prevalence in larger tumors and in those with a stronger ERα or PR staining.

Conclusions

The whole of the findings reported in the present study argue for an association between ERα and PR sex hormone receptor expression and a more aggressive presentation. Although no impact on outcome was found, the evaluation of ERα and PR receptor expression could add insights into the biological behavior of tumors and could modify the follow-up, particularly in fertile women affected with persistent disease.
Phosphodiesterases in the rat ovary: effect of cAMP in primordial follicles
Authors: Petersen Tonny Studsgaard , Stahlhut Martin , Andersen Claus Yding
Published: April 2015

Phosphodiesterases (PDEs) are important regulators of the intracellular cAMP concentration, which is a central second messenger that affects a multitude of intracellular functions. In the ovaries, cAMP exerts diverse functions, including regulation of ovulation and it has been suggested that augmented cAMP levels stimulate primordial follicle growth. The present study examined the gene expression, enzyme activity and immunolocalization of the different cAMP hydrolysing PDEs families in the rat ovary. Further, the effect of PDE4 inhibition on primordial follicle activation in cultured neonatal rat ovaries was also evaluated. We found varied expression of all eight families in the ovary withPde7bandPde8ahaving the highest expression each accounting for more than 20% of the total PDE mRNA. PDE4 accounted for 15–26% of the total PDE activity. Immunoreactive PDE11A was found in the oocytes and PDE2A in the corpora lutea. Incubating neonatal rat ovaries with PDE4 inhibitors did not increase primordial follicle activation or change the expression of the developing follicle markersGdf9,Amh,Inha, the proliferation markerMki67or the primordial follicle markerTmeff2. In addition, the cAMP analogue 8-bromo-cAMP did not increase AKT1 or FOXO3A phosphorylation associated with follicle activation or increase the expression ofKitlgknown to be associated with follicle differentiation but did increase theTmeff2,Mki67andInhaexpression in a dose-dependent manner. In conclusion, this study shows that bothPde7bandPde8aare highly expressed in the rodent ovary and that PDE4 inhibition does not cause an increase in primordial follicle activation.
Two new localities of the endangered fish Systomus martenstyni (Kottelat & Pethiyagoda, 1991) (Teleostei: Cyprinidae) found in Sri Lanka
Authors: Rajakaruna Shalini Lalanthika , Ellepola Gajaba , Gunaratne Thilanka , Madawala Sumedha , Ranawana Kithsiri
Published: April 2015

Systomus martenstyni is an endemic and endangered fish of Sri Lanka. This species was earlier known to be restricted to the Amban Ganga River basin. Recently two populations of S. martenstyni were located in two major tributaries of River Mahaweli: Loggal Oya and Badulu Oya in the Uva province of Sri Lanka. These new populations are relatively small and are facing the threat of habitat quality degradation and habitat loss. Effective conservation actions should be undertaken to conserve this endangered fish species.
CRESCIMENTO E SOBREVIVÊNCIA DE ESPÉCIES ARBÓREAS EM DIFERENTES MODELOS DE PLANTIO NA RECUPERAÇÃO DE ÁREA DEGRADADA POR DISPOSIÇÃO DE RESÍDUOS SÓLIDOS URBANOS1
Authors: Resende Luana Auxiliadora de , Pinto Lilian Vilela Andrade , Santos Eder Clementino dos , Silva Sueila
Published: April 2015

Objetivou-se, neste trabalho, avaliar o desenvolvimento silvicultural e a sobrevivência das espécies em diferentes modelos de plantio de mudas para recuperação da área do lixão de Inconfidentes – Sul de Minas Gerais/Brasil, a qual se encontra com deficiência de vegetação, o que proporciona impactos visual e ambiental, com o intuito de indicar diferentes espécies vegetais que possam ser ideais para serem utilizadas na requalificação dos lixões. O experimento foi instalado no delineamento estatístico inteiramente casualizado com quatro modelos de plantio envolvendo mudas de 11 espécies arbóreas nativas e da gramínea Chrysopogon zizanioides (M1- Leguminosas; M2- Leguminosas + Chrysopogon zizanioides; M3- nativas e M4- Eremanthus erytropappus e Nectandra lanceolata) e três repetições. As parcelas de 3 x 5 m de cada tratamento foram compostas por 15 mudas arbóreas, sendo acrescidas em cada modelo de plantio M2 oito mudas da gramínea Vetiver (C. Zizanioides). Foram avaliados ao longo de 20 meses a altura das plantas, o diâmetro do caule ao nível do solo, a área de copa e a sobrevivência, em intervalos de 30 dias. Os dados do crescimento silvicultural e sobrevivência entre os tratamentos e entre as espécies foram submetidos à análise de variância e as médias, comparadas pelo teste de Scott Knott a 5% de probabilidade. A partir da análise dos resultados da recuperação da área do desativado Lixão de Inconfidentes – Sul de Minas Gerais/Brasil, conclui-se que o modelo de plantio M2 e as espécies Bauhinia forficata, Eritrina falcata, Senna multijuga, Schizolobium parahyba e Schinus terebinthifoliussão as mais indicadas para recuperação da área.
DIFFERENTIAL RESPONSE OF CLONES OF EUCALYPT TO GLYPHOSATE1
Authors: Carvalho Leonardo Bianco de , Alves Pedro Luis da Costa Aguiar , Costa Flávia Regina da
Published: April 2015

Weed control is commonly performed by the inter-row mechanical weeding associated to intrarow glyphosate directed spraying, causing a risk for drift or accidental herbicide application, that can affect the crop of interest. The objective was to evaluate the response of clones C219, GG100, I144, and I224 of eucalypt (Eucalyptus grandis x E. urophylla) to glyphosate doses of 0, 18, 36, 72, 180, 360, and 720 g of acid equivalent per hectare. The clones showed different growth patterns with regard to height, leaf number, stem dry weight, relative growth rate, net assimilation rate, and relative leaf growth rate. The clones I144 and GG100 were more susceptible to glyphosate, showing the doses required to reduce dry weight by 50% of 113.4 and 119.6 g acid equivalent per hectare, respectively. The clones C219 and I224 were less susceptible to glyphosate, showing the doses required to reduce dry weight by 50% of 237.5 and 313.5 g acid equivalent per hectare, respectively. Eucalyptus clones respond differently to glyphosate exposure, so that among I224, C219, GG100, and I144, the susceptibility to the herbicide is increasing.
ESTUDIOS SOBRE EL COMPORTAMIENTO DE FORRAJEO DE Acromyrmex lundi Guering (HYMENOPTERA, FORMICIDAE) Y SU EFECTO SOBRE EL CRECIMIENTO DE PROCEDENCIAS DE Eucalyptus globulus Labill. (Myrtaceae)
Authors: Martínez Carmen Lidia , Virgala María Begoña Riquelme , Santadino Marina Vilma , Haro Ana María de , Barañao Justo José
Published: April 2015

El ataque de las hormigas cortadoras es una de las principales razones de pérdida de plantas durante la etapa de establecimiento de un monte forestal. Los objetivos de este estudio fueron evaluar la intensidad de forrajeo de Acromyrmex lundi asociado a algunas condiciones ambientales y procedencias de Eucalyptus globulus y estimar el impacto de la herbivoría sobre el crecimiento inicial de estos árboles. Dos ensayos se llevaron a cabo durante dos temporadas estivo-otoñales consecutivas, en el Campo Experimental de la Universidad Nacional de Luján, Argentina. Los materiales de diferentes procedencias fueron dispuestos en bloques equidistantes a 5 m de un nido activo de A. lundi. Durante doce semanas se contabilizó el número de hojas cortadas por las hormigas y se registraron algunas variables meteorológicas. En el segundo año la mitad de las parcelas fue protegida de las hormigas y se midieron variables de crecimiento. Los materiales de todas las procedencias fueron atacadas por A. lundi, aunque el número de hojas cosechada fue significativamente diferente sólo entre los orígenes Flinders Island (52,5 hojas) y Nullo Mountain (28,5 hojas). El número de días lluviosos fue el único factor ambiental que se relacionó positivamente con la actividad de las hormigas.Todos los tratamientos redujeron significativamente la altura, el diámetro y el área foliar cuando fueron atacados por las hormigas. Las distintas procedencias compensaron diferencialemnte la herbivoría. Se discuten los resultados en función de los criterios a tener en cuenta para la selección de materiales genéticos como herramienta de manejo y control del ataque de A. lundi.
EFEITO DA ADIÇÃO DE RESÍDUOS DE PODA DA ERVA-MATE EM PAINÉIS AGLOMERADOS
Authors: Carvalho Amelia Guimarães , Andrade Bruno Geike de , Cabral Carla Priscilla Távora , Vital Benedito Rocha
Published: April 2015

O objetivo deste trabalho foi avaliar a viabilidade técnica da utilização de resíduos da poda de erva-mate na produção de painéis aglomerados. Foram produzidos painéis de aglomerados nas seguintes composições: 100% de pinus (T1), 100% de resíduos de erva-mate com casca (T2), 100% de resíduos de erva-mate sem casca (T3), 50% de pinus com 50% de resíduos de erva-mate com casca (T4) e 50% de pinus com 50% de resíduos de erva-mate sem casca (T5). Os painéis foram produzidos com o adesivo ureia-formaldeído a um teor de 8%, com ciclo de prensagem de 8 min, a 170 ºC e 30 kgf.cm-2. Os painéis produzidos com os resíduos de erva-mate apresentaram menor umidade de equilíbrio higroscópico (UEH), assim como menor absorção de água após 24 h de imersão (AA 24 h). Não houve diferença estatística entre os tratamentos quanto às propriedades de compressão, arrancamento de parafusos, dureza Janka e ligação interna. Os painéis produzidos com resíduos de erva-mate, assim como as misturas deles com partículas de pinus, apresentaram valores de módulo de ruptura à flexão estática inferiores aos estipulados pela norma brasileira NBR 14810-2 (ABNT, 2002). Como não atenderam a um dos requisitos mínimos, painéis produzidos com resíduos de erva-mate não devem ser utilizados em substituição aos painéis de madeira aglomerada.
Incompatibilidade de enxertia induz aumento da suscetibilidade de cultivares de pessegueiro à Xanthomonas arboricola pv. Pruni
Authors: Pereira Ivan dos Santos , Antunes Luis Eduardo Corrêa , Picolotto Luciano , Fachinello José Carlos
Published: April 2015

O objetivo deste trabalho foi avaliar a compatibilidade de enxertia, a suscetibilidade à bacteriose e a frutificação de oito combinações, assim como, a influência da compatibilidade sobre a severidade da doença e a frutificação do pessegueiro. O experimento foi realizado ao nível de campo, sob infecção natural da bactéria, no Centro Agropecuário da Palma, pertencente à FAEM/UFPel, em Capão do Leão-RS. Foram avaliadas as combinações entre as cultivares 'Chimarrita' e Maciel e os porta-enxertos 'Aldrighi', 'Capdeboscq', 'Tsukuba 1' e 'Umezeiro'. O pomar foi implantado em delineamento experimental de blocos casualizados com quatro repetições, sendo cada unidade experimental composta de cinco plantas. Foi avaliada, a compatibilidade de enxertia, o diâmetro do caule, a severidade de dano e o índice de doença, a área foliar e a frutificação. As combinações entre as cultivares 'Chimarrita' e 'Maciel' e o porta-enxerto 'Umezeiro', apresentaram menor compatibilidade de enxertia, maior severidade de dano e índice de bacteriose, além de menor frutificação que as demais. Os resultados obtidos possibilitaram concluir que as combinações 'Chimarrita'/'Umezeiro' e 'Maciel'/'Umezeiro' são incompatíveis, além de, mais suscetíveis à bacteriose e menos produtivas, comparadas às demais. Pode-se dizer também, que a incompatibilidade de enxertia induz maior suscetibilidade das plantas à infecção por bacteriose, resultando em maior severidade da doença e menor frutificação
Fears and concerns related to menstruation: a qualitative study from the perspective of gender
Authors: Botello-Hermosa Alicia , Casado-Mejia Rosa
Published: April 2015

The aim of this article is to analyze the fears about menstruation and health that have been passed down to us by oral transmission from a gender perspective. A qualitative study, whose design was the Grounded Theory, performed in Seville, Spain, with 24 rural and urban women from different generations, young (18-25, 26-35 years), middle aged (36-45, 46-55, 56-65 years) and elderly (> 65 years). The semi-structured interview was used as a data collection technique. The discourses were subjected to content analysis, following the steps of Grounded Theory. The results highlight the abundant fears related to use of water during menstruation, with very harmful effects to health. As a conclusion to highlight the lack of women's knowledge about reproductive health and that despite Health Education campaigns there are still ancient misconceptions present about menstruation.
Characteristics of antenatal care for adolescents from state capitals in Southern and Northeastern Brazil
Authors: Fernandes Rita Fernanda Monteiro , Meincke Sonia Maria Könzgen , Thumé Elaine , Soares Marilu Correa , Collet Neusa , Carraro Telma Elisa
Published: April 2015

Quantitative and descriptive study that intended to describe some aspects of antenatal care for adolescents at teaching hospitals in the South and Northeast of Brazil, based on the quality criteria established by the Humanization Program of Antenatal and Birth Care. This is an excerpt from the research "Social support networks for fatherhood during adolescence". The data collection occurred between December 2008 and December 2009. The sample consisted of 559 puerperal adolescents. The results showed that 98% of the interviewees received antenatal care, 67.2% attended six or more consultations and 62.5% started the care in the first pregnancy terms. As regards the routine exams, not all of them were done, and 41.8% denied having received any kind of information about labor and delivery during the antenatal consultations. In conclusion, most of the adolescents received antenatal care according to the criteria recommended in the Program. Nevertheless, educational actions and orientations are needed during the consultations.
Violence against women commited by intimate partners: (in)visibility of the problem
Authors: Acosta Daniele Ferreira , Gomes Vera Lúcia de Oliveira , Fonseca Adriana Dora da , Gomes Giovana Calcagno
Published: April 2015

The objective is to identify the reasons behind violence against women and describe the acts perpetrated by an intimate partner. Documentary study, qualitative conducted at the Special Police Service to Women. We analyzed 902 occurrences between August/2009 and December/2011, whose victims had at least eighteen years old. We collected the data of occurrences, transcribing literally, stories of the victims and treating it them through the content analysis. It was observed as triggers of violence: male supremacy as a generator of suffering and submission; problems arising from drug use, problems related to children and division of assets. The severity was scaled for the consequences to the victim and their family. The nursing staff as part of the support network , need to understand this phenomenon as a health problem and strive to break through the barriers that impede effective and efficient service , assisting in the strengthening of women's autonomy and including men in combat actions and prevention of violence against women.
Old age from the perspective of elderly individuals of different nationalities
Authors: Faller Jossiana Wilke , Teston Elen Ferraz , Marcon Sonia Silva
Published: April 2015

The study aimed to understand how elderly from several nationalities who reside in Brazil conceive the old age and experience the aging process. It was used the Symbolic Interactionism and the Grounded Theory as a theoretical and methodological strategy. The informants were 33 elderly people who reside in Foz do Iguaçu-PR. The results show an old age conception marked by chronological, physical, psychological, behavioral aspects and also by the presence of disease, dependence, inability to work and by situations experienced over the years in the Brazilian context. The way to experience the old age is influenced by the homeland culture, but is related to the quality and to the conditions of life (autonomy, physical and financial dependence), the work valorization, the religious precepts and the family ties/relationships. It was concluded that to conceive and experience the old age, besides the cultural aspects, it's focused on the experiences and singular interactions occurred over the years and that gain significant contours according to the context and the time of life.
Procedures after exposure to biological material in a specialized cancer hospital
Authors: Luize Paula Batista , Canini Silvia Rita Marin da Silva , Gir Elucir , Toffano Silmara Elaine Malaguti
Published: April 2015

Occupational accidents involving biological material are a concern for healthcare facilities due to the severe harm they may cause to healthcare workers. This cross-sectional study's aim was to identify the behavior reported by nursing professionals in response to biological material exposure in a cancer hospital located in São Paulo, Brazil. The population was composed of 441 professionals. The hospital's Institutional Review Board approved the project. Of the 441 interviewed subjects, 82 (18.6%) reported exposure in the last twelve months. Note that 47 (57.3%) workers officially reported the accident and sought specialized clinical care. The most frequently reported reason by those (72.1%) who did not follow the protocol was considering it unnecessary. Strategies intended to improve adherence of healthcare workers to the recommended protocol may improve occupational safety.
Nursing informatics: unveiling the computer use by nurses
Authors: Matsuda Laura Misue , Évora Yolanda Dora Martinez , Higarashi Ieda Harumi , Gabriel Carmen Silvia , Inoue Kelly Cristina
Published: April 2015

Study conducted with the objective of understanding the assistant nurses' perception of a philanthropic institution about the computer use at work. The data collection happened in January 2013, through interviews with 12 nurses who answered the question: tell me about the computer use at your work. The data were treated using the content analysis technique, in which emerged the following theme categories and subthemes: Realizing positive aspects on computer use (nine subthemes); Realizing negative aspects on computer use (four subthemes); Suggesting actions to improve computer use (six subthemes); and Evaluating the computerization at work (three sub-themes). It was possible to conclude that the nurses have the perception that the computer use is related to the easily; the agility and practicality in development of professional activities; but there are technical and operational aspects that still need to be improved.
Women victims of domestic violence: a phenomenological approach
Authors: Oliveira Patrícia Peres de , Viegas Selma Maria da Fonseca , Santos Walquíria Jesusmara dos , Silveira Edilene Aparecida Araújo da , Elias Sandra Cristina
Published: April 2015

The aim of this study was to understand the experiences of women victims of domestic violence. The study entailed phenomenological research based on the theoretical framework of Maurice Merleau-Ponty, developed with ten women who were victims of domestic violence treated at a women's healthcare center in a municipality in the interior of the Brazilian state of São Paulo. Nuclei of meanings emerged from the statements, based on the analysis of the phenomenon of violence from the interviews, and led to the following themes: living with fear; living with physical injuries; and the decision to file a report after the violence experienced. The results showed that the experience lived and contained in these women's bodies enabled each one of them to evaluate their own existence, arousing the desire to leave the situation in order to exercise their role in the world. Thus, their bodies instrumentalized their beings, and allowed them to break the cycle of domestic violence.
Health needs: the interface between the discourse of health professionals and victimized women
Authors: Oliveira Rebeca Nunes Guedes de , Fonseca Rosa Maria Godoy Serpa da
Published: April 2015

Objective: to understand the limits and the evaluative possibilities of the Family Health Strategy regarding the recognition of the health needs of women who experience violence. Method: a study with a qualitative approach, grounded in the perspective of gender, and which adopted health needs as the analytical category. The data were collected through interviews with health professionals and women who made use of a health service, and were analyzed using the method of discourse analysis. Results: the meeting between the discourses of women who use the services and the professionals of the health service revealed, as the interface, human needs, as in the example of autonomy and of bonds. The understanding regarding the needs was limited to the recognition of health problems of physical and psychological natures, just as the predominance of the recognition of needs for maintaining life in the light of essentially human needs was revealed in the professionals' discourses as an important limitation of the practices. Conclusion: emphasis is placed on the perspective of gender as a tool which must be aggregated to the routine of the professional practices in health so as to confirm or deny the transformative character of the care in place regarding the recognition and confronting of the women's health needs.
Blended learning e as mudanças no ensino superior: a proposta da sala de aula invertida
Authors: Valente José Armando
Published: April 2015

As tecnologias digitais de informação e comunicação (TDIC) proporcionaram importantes mudanças na educação a distância, que até o início dos anos 1980 era baseada no material impresso produzido e enviado aos alunos. Com as tecnologias foram criadas diversas modalidades de ensino a distância, inclusive o blended learning, que combina atividades presenciais e atividades educacionais a distância, realizadas por meio das TDIC. Há diferentes maneiras de combinar as atividades presenciais e a distância, sendo a sala de aula invertida ou flipped classroom uma delas. Segundo essa abordagem, o conteúdo e as instruções sobre um determinado assunto curricular não são transmitidos pelo professor em sala de aula. O aluno estuda o material antes de ele frequentar a sala de aula, que passa a ser o lugar de aprender ativamente, realizando atividades de resolução de problemas ou projetos, discussões, laboratórios etc., com o apoio do professor e colaborativamente dos colegas. O objetivo do artigo é discutir as diferentes modalidades do blended learning e da sala de aula invertida, como as TDIC são usadas em diferentes modelos de implantação dessa abordagem pedagógica, como a sala de aula invertida pode ser implantada e os pontos positivos e negativos sobre a sala de aula invertida apresentados por diferentes autores.
Os benefícios da utilização das TIC no Ensino Superior: a perspetiva docente na E-Learning
Authors: Trindade Rui
Published: April 2015

Este é um artigo através do qual se analisam os projetos que receberam o prémio Excelência E-Learning da Universidade do Porto (Portugal), atribuído entre 2004/2005 e 2010/2011, a partir dos benefícios que os docentes atribuíam à utilização das novas Tecnologias de Informação e Comunicação (TIC) como suportes de iniciativas pedagógicas em contextos de formação relacionados com o Ensino Superior. Trata-se de um estudo onde se conclui que estamos perante um campo marcado por tensões, equívocos e contradições diversos, o que tem mais a ver com os pressupostos concetuais e epistemológicos das abordagens pedagógicas que, hoje, têm lugar no Ensino Superior do que propriamente com a reflexão específica sobre a utilização das TIC num tal contexto, a qual é afetada pelo modo como aquelas abordagens são construídas.
A formação de jovens do campo e o vínculo entre conhecimento, trabalho e educação: um estudo do Colégio Estadual do Campo Iraci Salete Strozak
Authors: Janata Natacha Eugênia
Published: April 2015

O acesso ao conhecimento e a relação escola e vida tem sido uma temática presente nos estudos acerca da proposta educacional do Movimento dos Trabalhadores Rurais Sem Terra (MST). Neste texto abordamos a especificidade da formação de jovens do campo, considerando a relevância dessa conexão. Apresentamos dados de pesquisa de doutorado em educação que buscou compreender o entrecruzamento do trabalho, escolarização e militância de egressos de uma escola de assentamento do MST e sua relação com a formação dos jovens, sobretudo, os militantes. Para tanto, realizamos entrevistas semiestruturadas com 22 egressos, lideranças e equipe diretiva da escola, além de análise do Projeto Político Pedagógico. Caracterizamos a instituição investigada, destacando as problemáticas acerca do acesso ao conhecimento e a relação trabalho e educação na formação dos jovens. Concluímos identificando os limites da escola, compreendendo-a no interior das relações capitalistas de produção da vida, bem como ressaltando as possibilidades que o vínculo entre trabalho e educação no acesso ao conhecimento traz para a constituição de jovens do campo que compreendem as contradições e se comprometem com as lutas da classe trabalhadora, em especial a do MST.
The Landless Voices Database: A Trajectory from Cultural Studies to Pedagogical Impact
Authors: Vieira Else R. P.
Published: April 2015

This article initially addresses the conception of the web-enabled database Landless Voices (Vieira, 2003) as a contribution to Cultural Studies and, crucially, to the understanding of the relational workings of Brazil's complex and regionally diverse culture of landlessness, and to the validation of the cultural self-expression of the sem-terra/Sem Terra. Secondly, it analyzes speculative data obtained from prospective primary teachers being trained at the Federal University of Paraná, Brazil, on the contribution of the database to the pedagogical context. The main findings are that the three predominant types of impact, using Meagher's terminology (2013, p. 5) are conceptual (new knowledge), cultural (revising misconceptions) and instrumental (future development of pedagogic practices). It then moves to empirical research on social impact, understood as the contribution of academic research to non-academic users, more specifically to its presumably main beneficiaries - the Sem Terra learners themselves. The findings of these first exploratory workshops with learners in four rural schools in settlements in the states of Paraná and São Paulo, respectively in October and November 2013, are that the database broadens their educational resources and empowers a historically marginalized social segment. This article confirms, however, that impact is not a punctual activity (Meagher, 2013) and concludes on the need for continuous interaction with learners for the pedagogic impact of academic research to be generated1.
MODELOS HIPSOMÉTRICOS GENERALIZADOS MISTOS NA PREDIÇÃO DA ALTURA DE Eucalyptus sp.
Authors: Mendonça Adriano Ribeiro de , Carvalho Samuel de Pádua Chaves e , Calegario Natalino
Published: April 2015

Conduziu-se, este trabalho, com o objetivo de avaliar a teoria dos modelos generalizados mistos e a modelagem da heterogeneidade de variância no ajuste de dois modelos não lineares para a relação altura-diâmetro em Eucalyptus sp. Foram utilizados dados de árvores-amostras de diferentes materiais genéticos (clone e semente) e idades. De acordo com as análises, o modelo assintótico obteve os melhores resultados em relação ao modelo sigmoidal. A precisão dos modelos avaliados aumentou com a utilização da teoria dos efeitos mistos com adição de covariáveis e a modelagem da heterogeneidade da variância.
CONCENTRAÇÃO E ACÚMULO DE NUTRIENTES EM POVOAMENTOS DE TECA NO ESTADO DE MATO GROSSO, BRASIL
Authors: Rosa Tania de Fátima de Deus , Scaramuzza Walcylene Lacerda Matos Pereira , Silva Renata Gonçalves da
Published: April 2015

O conhecimento das necessidades nutricionais de uma cultura é essencial para a elaboração das recomendações de adubação. Assim, neste estudo, objetivou-se estimar a concentração e o acúmulo de nutrientes na serapilheira de teca com diferentes idades. A pesquisa foi realizada em Nossa Senhora do Livramento - MT, durante os meses de setembro de 2008 a agosto de 2009, em três talhões dos povoamentos de teca com idades de cinco, seis e sete anos, onde foram instalados 20 coletores de madeira suspensos a 30 cm de altura do solo, com 0,64 m2 de área. A cada 30 dias, os conteúdos dos coletores foram recolhidos e separados manualmente em folhas, galhos e miscelâneas (cascas, flores e frutos). Cada fração foi seca em estufa de circulação forçada de ar a 70° C até peso constante, em seguida foram pesadas, moídas e acondicionadas em sacos plásticos para posterior análise dos nutrientes. A ordem de magnitude na transferência de nutrientes pela serapilheira ao solo em função das frações ficou representada para as folhas Ca>N>Mg>K>P>S; galhos N>Ca>K>Mg>S>P; e miscelânea N>Ca>K>Mg>P>S. A magnitude de nutrientes nas frações correspondeu à folhas>galhos>miscelânea. A ordem de concentração dos nutrientes e de acúmulo nas plantas foi semelhante em todas as idades: Ca>N>K>Mg>P>S.
EQUAÇÕES ALOMÉTRICAS EM PLANTIOS MISTOS VISANDO À RESTAURAÇÃO DA FLORESTA ESTACIONAL SEMIDECIDUAL
Authors: Ré Danilo Scorzoni , Engel Vera Lex , Ota Liz Miyo Sousa , Jorge Luiz Alberto Blanco
Published: April 2015

Visando a suprir a lacuna do conhecimento existente sobre a estimação precisa do potencial de produção madeireira de sistemas de restauração florestal, com o presente trabalho, objetivou-se modelar as relações alométricas (hipsométricas e volumétricas) de nove espécies comuns a modelos alternativos de restauração da floresta estacional semidecidual. Os modelos se ajustaram bem aos dados coletados e a análise de resíduos indicou distribuição satisfatória, tanto para os modelos hipsométricos como volumétricos. O modelo hipsométricos de Stoeffels e o modelo volumétrico de Schumacher-Hall foram os mais flexíveis, ajustando melhor para várias espécies. Essas equações obtidas serão usadas em futuros estudos de manejo e conservação de áreas em restauração.
EFEITO DA VAPORIZAÇÃO NA SECAGEM DE TÁBUAS DE Eucalyptus grandis
Authors: Rezende Raphael Nogueira , Lima José Tarcísio , Paula Luana Elís de Ramos e , Silva José Reinaldo Moreira da
Published: April 2015

Neste trabalho, objetivou-se avaliar o efeito da vaporização na taxa de secagem e na qualidade da secagem de tábuas de Eucalyptus grandis. Para isso, utilizou-se uma madeira proveniente de um plantio da Universidade Federal de Lavras, MG, Brasil, com idade de 24 anos. Árvores foram abatidas e suas toras foram desdobradas por um sistema de corte tangencial. Dividiu-se a carga de tábuas à metade, sendo uma delas para secagem com vaporização e outra sem vaporização. Na secagem com vaporização, após a fase de aquecimento, houve um tratamento de 3 horas a 90ºC e 100% de umidade relativa. A secagem ocorreu em estufa de secagem convencional e foram realizadas medições de defeitos e determinação da taxa de secagem. Os resultados indicaram que a vaporização foi eficiente, aumentando a taxa de secagem em 15% e reduzindo defeitos de secagem de 20 a 52%.
Mixed adenoneuroendocrine carcinoma of the gastric stump following Billroth II gastrectomy: case report and review of the literature
Authors: Cazzo Everton , Saito Helena Paes de Almeida de
Published: April 2015

CONTEXT: Gastric stump cancer after gastric resection is a well-known disease. It may be a newly developed cancer after resection due to benign disease, or recurrent or residual disease after oncological surgery. The predominant histological type is usually adenocarcinoma. This study aimed to report on a rare occurrence of a mixed adenoneuroendocrine carcinoma (MANEC) on the gastric stump. CASE REPORT: The case of an 83-year-old female who presented a locally aggressive gastric stump MANEC, 35 years after Billroth II gastrectomy to treat a peptic ulcer, is reported. The patient underwent resection and adjuvant therapy. She has been followed up for one year without signs of recurrence. CONCLUSION: MANEC is a rare type of gastrointestinal neoplasm. The classification, histopathology, clinical features, treatment issues and prognosis are discussed along with a brief review of the literature.