bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluation of Neutrophil Gelatinase-Associated Lipocalin and Cystatin C in Early Diagnosis of Chronic Kidney Disease in the Absence of the Gold Standard
Authors: Azizmohammad Looha Mehdi , Masaebi Fatemeh , Wang Zhuoyu , Zarean Elaheh , Nasiri Maliheh , Kazerouni Faranak , Gharishvandi Fatemeh , Zayeri Farid
Published: December 2023

Background: Glomerular filtration rate (GFR) is considered as a gold standard of kidney function. However, using GFR as the gold standard is not common in clinical practice, because its direct measurement is usually expensive, cumbersome, and invasive. In the present study, we assessed the predictive power of two other biomarkers, Cystatin-C (Cys-C) and Neutrophil Gelatinase-Associated Lipocalin (NGAL) for early detection of chronic kidney diseases (CKD) in the absence of a gold standard. Materials and Methods: In this study, 72 patients who referred to the Shohadaye Tajrish Hospital of Tehran, Iran, for measuring their kidney function were studied. The ELISA method was utilized for measuring plasma NGAL (PNGAL) and serum Cys-C (SCys-C). The Bayesian latent class modeling approach was applied to asses the predictive power of these biomarkers. Results: While both the biomarkers had rather high sensitivities (PNGAL=91%, SCys-C= 89%), the specificity of SCys-C biomarker was very lower than the one of PNGAL (SCys-C=56%, PNGAL=94%). The estimated area under the receiver operating characteristic (ROC) curve for SCys-C as the single biomarker for the diagnosis of CKD was about 0.76, while a similar estimate for PNGAL was 0.93. The added value of PNGAL to SCys-C for the diagnosis of CKD in terms of the ROC curve was about 0.19, while the added value of SCys-C to PNGAL was less than 0.02. Conclusion: In general, our findings suggest that PNGAL can be utilized as a single reliable biomarker for early detection of CKD. In addition, results showed that when a perfect gold standard is not available, Bayesian approaches to latent class models could lead to more precise sensitivity and specificity estimates of imperfect tests. [GMJ.2020;9:e1698]
Successful Removal of a Biliary Stent in the Jejunum Using Double-Balloon Enteroscopy
Authors: Saeedi Sandra , Dooghaie Moghadam Arash , Razavi-Khorasani Niloofar , Eslami Pegah , Farokhi Ermia , Moazzami Bobak , Mehrvar Azim , Iravani Shahrokh , Reza Hashemi Mahmood , Dooghaie Moghadam Masoud
Published: December 2023

Background: Plastic biliary stent placement has been widely used as a safe approach for the management of hilar neoplasms or the dilation of benign biliary obstruction. Despite the complexity of this procedure, this approach is followed by a few complications. The incidence rate of stent migration is about 10%. In a majority of cases, the migrated stents are retained within the gastrointestinal tract and pass through the intestine with no complication or need for medical intervention. Case Report: In this paper, we described the case of the migrated biliary stent with prolonged abdominal pain, which was removed successfully by using double-balloon. Conclusion: In the case of patient with prolonged abdominal pain and previous history of biliary stent placement, migration of stent should be considered as differential diagnosis and Double-Balloon Enteroscopy can be a safe approach in those cases.[GMJ.2020;9:e1809]
Evaluation of Impacts of Cellular Metabolism on the Migration of Ovarian Cancer Cells by Two in Vitro Assays: A Method Comparison Study
Authors: Salami Siamak , Ghahremani Hossein , Sirati-Sabet Majid
Published: December 2023

Background: Alteration of metabolic pathways in cancer cells can intensely modulate their migration as an important step in invasion and metastasis. Ketogenic diet showed some contradictory results in cancer patients. In this study the impact of metabolic reprogramming of A2780CP as a model of ovarian cancer stem-like cells on cell migration by two in vitro methods: wound healing and soft agar colony-forming assays. Materials and Methods: short term and long term metabolic reprogramming were done by restriction of glucose to 250mg/L with or without enrichment with beta-hydroxybutyrate (5 milimolar) for 48 hours and 30 days, respectively. Wound healing assay was done and the wound ratio was calculated for 24 and 48 hours. Soft agar colony formation assay was also done in treated and control cells. For method comparison, ten biological replicates were analyzed in triplicate. Results: Migration of A2780CP ovarian cancer stem-like cells were significantly alleviated by long term glucose restriction but no significant changes were observed in short term study. Beta-hydroxybutyrate enrichment did not produce significant impacts on glucose restriction in short or long term studies. Conclusion: The results of colony formation in soft agar and wound or scratch healing assay were in good correlation and convergence which could be used interchangeably in the investigation of metabolic reprogramming in cancer cells. [GMJ.2020;9:e1831]
Effect of 5-aza-2Ëˆ-deoxycytidine on p27Kip1, p21Cip1/Waf1/Sdi1, p57Kip2, and DNA methyltransferase 1 Genes Expression, Cell Growth Inhibition and Apoptosis Induction in Colon Cancer SW 480 and SW 948 Cell Lines
Authors: Kavoosi Fraidoon , Sanaei Masumeh , Nasiri Sedighe
Published: December 2023

Background: Dysregulation of the cell cycle has been reported in various cancers. Inactivation of the cyclin-dependent kinases inhibitors (CDKIs), CIP/KIP family, such as p21Cip1/Waf1/Sdi1, p27Kip1, and p57Kip2 genes because of hypermethylation has been shown in several cancers. Treatment with DNA demethylating agent 5-aza-2Ëˆ-deoxycytidine (5-Aza-CdR) has been indicated that affect genomic methylation and resulting in silenced genes reactivation in colon cancer. Previously, we evaluated the effect of 5-Aza-CdR on DNA methyltransferase 1 (DNMT1) gene expression in hepatocellular carcinoma (HCC) which encouraged us to design the current study. The present study aimed to evaluate the effect of 5-Aza-CdR on p21Cip1/Waf1/Sdi1, p27Kip1, p57Kip2, and DNAT1 genes expression, cell growth inhibition and apoptosis induction in colon cancer SW 480 and SW 948 cell lines. Materials and Methods: The effect of 5-aza-CdR on the SW 480 and SW 948 cells growth, apoptosis induction and genes expression were assessed by MTT assay, flow cytometry, and real-time quantitative reverse transcription-polymerase chain reaction (qRT-PCR) analysis respectively. Results: 5-aza-CdR inhibited cell growth as time- and dose-dependent manner significantly (P<0.001). The agent reactivated p15INK4, p16INK4, p18INK4, and p19INK4 genes expression and induced apoptosis at a concentration of 5 Î¼M significantly. Besides, 5-aza-CdR had a more significant effect on the SW 480 cell line in comparison to SW 948 cell line. Conclusion: 5-Aza-CdR plays a key role in the up-regulation of p21Cip1/Waf1/Sdi1, p27Kip1, and p57Kip2 and down-regulation of DNMT1 genes resulting in cell growth inhibition and apoptosis induction. [GMJ.2020;9:e1899]
An investigation of using elaborated and metacognitive feedback strategies in interactive instructional videos
Authors: DİRİ KOÇ Ezgi , ÖNER Diler
Published: December 2023

The purpose of this study is to compare the use of elaborated and metacognitive feedback strategies in interactive instructional videos in terms of undergraduate students’ engagement and metacognitive awareness levels. This study also aims to investigate undergraduate students’ evaluations of elaborated and metacognitive feedback in these instructional videos based on qualitative data. This study used a basic randomized post-test-only experimental design comparing two treatments supported by qualitative data. The participants were 52 preservice teachers who registered for an undergraduate educational technology course offered by a faculty of education. They were randomly assigned to the metacognitive and the elaborated feedback groups. The data were collected with the Short Form of the User Engagement Scale and the Metacognitive Awareness Inventory. In addition, qualitative data were collected through interviews and used to examine students’ evaluations of the elaborated and metacognitive feedback used in the interactive instructional videos. The results showed that there was no statistically significant difference between the two types of feedback in terms of students’ engagement and metacognitive awareness levels. The qualitative findings indicated that while the two types of feedback did not provide a significant superiority over each other, students viewed the two types of feedback as serving different purposes. Our findings suggest that customizing the type of feedback based on students' answers and subject mastery level, or a thoughtful integration of both types of feedback, could enhance the learning experience in interactive instructional videos.
ON SEKİZİNCİ YÜZYIL MAKAM TARİFLERİNDE NİM PERDELER
Authors: Budak Mehmet Alişan
Published: December 2023

Makam müziği teori tarihinde on sekizinci yüzyıl, Kantemir ile başlayıp Abdulbaki Nasır Dede tarafından farklı bir düzleme taşınan ve seyir odaklı makam tarifleri tercih edilen bir dönemi temsil etmektedir. Kantemir ile kurumsallaşan ‘tam perde’ ve ‘nim perde’ şeklindeki perde sınıflandırması; dönemin teorik yaklaşımının, ses malzemesini temelde ikiye böldüğüne işaret eder. Tam perdeler konusunda mutabakat sağlanmıştır, bununla birlikte ezgisel seyir içerisinde bu perdelerin hareket ettiklerine dair herhangi bir bilgi mevcut değildir. Diğer yandan ‘nim perdeler’ başlığı altındaki perdelerin hareketli olabildikleri belirtilirken; bu perdelerin nicelik, nitelik ve isimlendirme bakımından her kaynakta farklı bir yoruma tabi tutuldukları gözlemlenmektedir. Dahası Ali Ufkî ve Kantemir’in nota derlemelerinden görüldüğü kadarıyla, on yedinci yüzyıldan günümüze doğru gelindikçe nim perdelerin kullanım çeşitliliğinde ve makamsal geçki sıklığında belirgin bir artış söz konusudur. Bu durum, nim perdelerin süreç içerisinde makamsal ezgi üretiminin çeşitliliğini sağlamak adına fonksiyonel görev üstlendiklerinin somut bir göstergesidir. Bu çalışmada Kantemir, Nayi Osman Dede, Halaçoğlu, Marmarinos, Tanburi Artin, Kemani Hızır Ağa ve Abdülbaki Nasır Dede gibi on sekizinci yüzyıl teorisyenlerinin eserlerindeki nim perdelere ve bu perdelerin makam tarifleri içerisindeki kullanımlarına odaklanılmıştır. Tam perde aralarındaki ‘nim perde’ bölgelerinden edilen veriler birbirleriyle ilişkilendirilerek ele alınmıştır. Neticede nim perdeler vasıtasıyla dönem kaynaklarından günümüze gelinirken ‘sırf makamlar’ da konuya dahil ederek belirli çıkarımlarda bulunulmuştur.
GLOBAL WARMING AND SMALL CYCLE: RISKS AND PROSPECTS
Authors: Dent D. , Bai Zh.
Published: December 2023

Climate change is altering our understanding of ourselves, our society, the relationships between socio-economic and biophysical systems, and humanity's place on Earth. It is clear that the Earth is warming, but the scientific consensus for half a century has ignored the root cause of this threatening phenomenon, so the response has been ineffective and has not led to a consolidation of efforts. It is noted that the main reasons for the impact on the climate in the agro sector are the clearing of land for agriculture, the loss of year-round vegetation covering the soil, the reduction of forests, which expose the bare soil to solar radiation, creating tangible heat. The cooling effect of evaporation is limited or stopped by vegetation. This significantly changes formation and movement of moisture, stops rain from reaching deep into dry areas. In the article, the authors define the most important directions and some actions to solve the problem of bare soil surfaces.
The earth still behaves as if it is trying to preserve the most favorable environment for all living things. It follows that the safest and most sustainable land use should imitate natural vegetation. Farmers and other land users should avoid exposing bare soil to direct sunlight. For this purpose, it is proposed to minimize tillage (no tillage) leaving the plow; to implement various crop rotations, preferably with perennial crops; to form a motley, diverse landscape that promotes a small water cycle in agroecosystems. The present research identifies only some of the processes through which a bare or non-bare landscape affects weather and climate. The work confirms that the impact of soil stripping from vegetation on atmospheric processes should be taken into account in the policy of regional land management in agro landscapes around the world, and even where significant land clearing for agricultural purposes is impossible.
ФОРМУВАННЯ ПРОДУКТИВНОСТІ СОЇ (GLYCINE MAX (L.)) НА ДЕРНОВО-ПІДЗОЛИСТОМУ ҐРУНТІ ЗА РІЗНИХ ДОЗ УДОБРЕННЯ І МЕЛІОРАНТІВ
Authors: Польовий Володимир , Ященко Людмила , Ровна Галина
Published: December 2023

Соя займає провідне місце у світовому землеробстві. Серед низки агротехнічних заходів, що забезпечують реалізацію потенційних можливостей сортів важливе місце займає система удобрення. Враховуючи розширення площ її вирощування у зоні Західного Полісся проведено дослідження щодо формування індивідуальних показників продуктивності рослин сої як інтегрального показника дії різних доз добрив і меліорантів на дерново-підзолистому ґрунті. Методи дослідження: польовий, біометричний, статистичний. Дослідження проведені у стаціонарному досліді. Встановлено, що застосування добрив на фоні хімічних меліорантів стабілізує інтервал висоти рослин за коефіцієнта варіації V<5%. Виживання рослин у середньому склало 80,7–80,9% у варіантах N55P20К50 і N65P50K75 на фоні 1,0Нг та N45P60K60 на фоні 1,5 Нг CaMg(CO3)2, що більше контролю на 6,5–9,0%. Удобрення на фоні меліорантів сприяло підвищенню індивідуальної продуктивності рослин, найвищою вона була у варіанті N65P50K75 + S40 + мікродобриво (двічі) на фоні 1,0 дози Нг СaMg(CO3)2: кількість бобів 13,7шт., кількість зерен на рослині 30,1шт., маса 1000 зерен 166,6г, маса зерна з рослини 5,02г. Однак, дані величини не були значущими при р≤0,05 порівняно з дозою N55P20K50 за інших однакових умов. Регуляція показників структури сої за рахунок удобрення на фоні меліорантів зумовила вищу насіннєву продуктивність культури. У середньому за 2021-2022 р. найвищу 2,48 і 2,60т/га урожайність насіння забезпечили дози N55P20К50 і N65P50K75 із додаванням S40 + мікродобриво на фоні 1,0 Нг дози CaMg(CO3)2. Встановлено, що одностороннє внесення азотних добрив у дозі N55 із додаванням S40 + мікродобриво(двічі) на фоні 1,0 дози CaMg(CO3)2 підвищило урожайність на 58,9% до контролю і на 15,6% до фону, але значно поступалася варіантам повного мінерального живлення.
ЕФЕКТИВНІСТЬ ВИРОЩУВАННЯ ОСНОВНИХ СІЛЬСЬКОГОСПОДАРСЬКИХ КУЛЬТУР НА ЗВІЛЬНЕНИХ ВІД САДІВНИЦТВА ҐРУНТАХ ЗА ЇХНЬОГО ОПТИМІЗОВАНОГО УДОБРЕННЯ
Authors: Мельник В. , Разанов С. , Приймак Ю.
Published: December 2023

Одним із головних заходів щодо підвищення економічної ефективності виробництва основних сільськогосподарських культур після викорчовування саду є забезпечення рослин основними елементами живлення (азот, фосфор, калій), використання раціонального, науково обґрунтованого мінерального удобрення ґрунтів з огляду на наявність у них поживних речовин. Вивчено переведення ґрунтів після багаторічних насаджень у використання під польову сівозміну на сірих лісових ґрунтах для вирощування основних сільськогосподарських культур під заплановану врожайність за оптимізованого удобрення на прикладі господарства Вінницької області в умовах Лісостепу Правобережного України. Економічну ефективність елементів технології вирощування сільськогосподарських культур розраховували за середньозваженими реалізаційними цінами на вирощену продукцію та цінами на мінеральні добрива на 2021 рік. Норми внесення мінеральних добрив розраховано під заплановану врожайність пшениці озимої на рівні 7,0т/га, кукурудзи – 11,2т/га, та соняшнику – 3,5т/га, враховуючи наявні у ґрунті поживні речовини.
Встановлено, що у варіанті після інтенсивного садівництва ґрунт потребував більшої кількості добрив. Так, за вирощування пшениці озимої спостерігали збільшення виробничих витрат на вирощену продукцію на 1636 грн/га, для кукурудзи – на 2041,5 грн/га, та для соняшнику – на 2132 грн/га порівняно з варіантом після екстенсивного саду. Встановлено, що у варіанті за вирощування після екстенсивного садівництва пшениці озимої, кукурудзи та соняшнику відзначається зростання врожайності на 0,397; 0,497 та 0,107т/га відповідно. Виявлено, що після екстенсивного садівництва рівень рентабельності був більший на 27,9% за вирощування озимої пшениці, на 29,4% за вирощування кукурудзи та на 31,5% – соняшнику.
AMASYA YÖRESİ TÜRKÜLERİNDE ALEVİ-BEKTAŞİ UNSURLARI VE BU ESERLERİN MÜZİKAL ANALİZLERİ
Authors: YÜCEL Haluk
Published: December 2023

Türküler, Türk insanının dini ve dindışı tüm duygularına tercüman olmuştur. Kahramanlık, savaşlar, ölüm, aşk, sevda, ayrılık gibi konular her yörede âşıklar tarafından dile getirilirken kimi zamanda dini metinler, tasavvufi temalar ve Alevi-Bektaşi söylemleri türkülerde konu edilmektedir. Dini boyutu olduğu kadar toplum yaşamının biçimlendirilmesinde de önemli bir etken olan bu unsurlar Amasya türkülerinde kendine yer bulmuştur. Gerek yazılı gerekse sözel aktarımlar sayesinde olsun bir toplumun yaşayan hafızası kabul edilen türküler, konuları, içerikleri ve gelecek kuşaklara vereceği mesajlarıyla içinde yaşadığı yörenin en önemli tarihi ve sosyo-kültürel zenginliklerindendir. Amasya türküleri tematik olarak incelendiğinde ayrılık, aşk ve sevda konulu türküler ilk sırada yer almaktadır. Bununla birlikte ağıt temalı türküler ve semah karakterli eserler de mevcuttur. Sözlü kültürün aktarımında halk müziğinin, âşıkların, dinsel ve dilsel özelliklerin önemi tartışılmaz. Çünkü türküler tıpkı gelenek gibi kuşaktan kuşağa, kalpten kulağa intikal eder. Bu çalışmada Amasya türkülerinde geçen Alevi-Bektaşi unsurları incelenmekte aynı zamanda tespit edilen türkülerin müzikal analizleri de çalışmada yer almaktadır. Çalışmada kullan ana kaynaklar arasında TRT Türk Halk müziği arşivi, TRT Müzik Dairesince hazırlanan Amasya Türküleri CD’si ve Amasya Belediyesi tarafından basılmış olan “Amasya Türküleri” kitabıdır. Çalışmada yaklaşık 40 Amasya türküsü incelenmiş ve bu türkülerde geçen Alevi-Bektaşi unsurları bulgular kısmında ele alınmıştır.
Языковая личность писателя Яныбая Хамматова (на материале художественных текстов)
Authors:   Ордена Знак Почета Институт истории, языка и литературы Уфимского федерального исследовательского центра Российской академии наук, Ишегулова Алсыу Минифариевна
Published: December 2023

Монография посвящена анализу особенностей языковой личности Яныбая Хамматова – одного из ярких башкирских прозаиков второй половины XX века. В работе осуществлен лексический, стилистический, синтаксический анализ языковых единиц, выявлены и охарактеризованы ключевые слова-концепты, проанализированы значимые прецедентные феномены в структуре языковой личности писателя. Книга предназначена всем, кто интересуется проблемами формирования языковой личности.
Kesadaran Masyarakat Dalam Mengurangi Bencana Banjir Dilihat Dari Aspek Hukum Di Sumatera Selatan
Authors: Warsari Dwi , Iswan Joni
Published: December 2023

Indonesia is a country that is prone to disasters. Based on BNPB data, from 2018 to 2019 there were 3,999 disasters. The total potential area of ​​flood hazard in South Sumatra Province as a whole is 6,476,932.00 Ha and is in the High class. The extent of flood hazards is broken down into 3 hazard classes. In reality, the survey results show that knowledge of disasters in Indonesia is still not accessible to the general public. There is a gap between disaster knowledge and existing knowledge at the community level. This is proven by the community's lack of responsiveness in protecting the surrounding environment, their lack of response to natural phenomena and their tendency to wait for the government to handle disasters. The success of this strategy is expected to increase public awareness of disasters so that they actively participate in flood prevention. The data collection technique used is in the form of a questionnaire or questionnaire. The results show that children who have environmental awareness in Plaju District are only around 50.57%. The value of children's environmental awareness based on the results of the questionnaire is still low, namely 49.86%. And from the survey results, the government must raise environmental awareness among the people of Plaju sub-district, which must be done by the government, the managers (RT/RW), one of which is the need for support and motivation from related parties such as the government in the form of counseling and providing capital to encourage its citizens to process waste into something useful. useful so that it can convince residents by creating jobs and minimizing waste.
Non-Governmental Organizations in Contemporary China: political and legal aspect
Authors: Troshchinskiy Pavel
Published: December 2023

The article is devoted to the study of general issues of the non-governmental public organizations in China. The current legislation regulating their legal status is being considered, including law-making acts adopted since the beginning of the "policy of reform and openness". In the Soviet type countries, to which the People's Republic of China belongs, the work of non-governmental organizations cannot conflict with the course of the ruling party. In the PRC, public organizations act as an integral part of a United Front led by the CPC and consisting of various political forces striving for a common goal — the "great revival of the Chinese nation." The activities of opposition public organizations in China are prohibited, and their registration is impossible. The Chinese authorities believe that the interests of the collective are above the interests of the individual, therefore, individuals that do not obey the "mass line" do not have the right to exist. Western experts believe that the absence of oppositional, state-independent public organizations in China does not allow them to be classified as non-governmental. However, Chinese specifics are overlooked, which leads to an incorrect transfer of Western concepts and institutions to Chinese soil and, consequently, allegations of an insufficient degree of democratization of China. The study provides up-to-date statistics on the number of non-governmental public organizations in China in recent years.
Transformation of the Physician-patient Relationship: From Bioethics to Roboethics
Authors: Vvedenskaya Еlena.V.
Published: December 2023

In the context of the active development and implementation of artificial intelligence systems and robotics in healthcare, the physician-patient relationship is undergoing changes. The transformation of these relations caused by the problems of interrelation of the basic bioethical principles and new approaches to the diagnosis and treatment of diseases is considered. Using concrete examples, new opportunities and risks caused by the widespread use of automation in medicine are revealed. Conflict situations between human norms and algorithms are analyzed. The issues of responsibility for robot errors, as well as privacy and cybersecurity issues are considered. It is noted that by the beginning of the 21st century, there was a need for an ethical assessment of robotics, since technical decisions taken in the design of robots have the potential to directly and significantly affect people's lives. In this regard, roboethics arose, the concept of which is analyzed in the article. The laws of robotics were formulated by I. Asimov and F. Pasquale. At the same time, attention is drawn to the fact that in the field of healthcare, programs should be developed that rely on human strength. The necessity of finding a balance between the automation of medical practice and the maintenance of the humanistic essence of the physician-patient relationship is emphasized. A comparative analysis of the fundamental principles of bioethics and roboethics is carried out. Despite the fact that they have the same goals and values, in roboetics these principles are characterized by a number of features. The principle related only to roboethics — explainability — requires algorithm developers to explain the general rationale and methodology for solving artificial intelligence. In conclusion, it is concluded that medical robotics and artificial intelligence systems provide great prospects for improving diagnosis, treatment and the general level of medical care, but their use raises important ethical issues that need to be addressed. The basic principles of bioethics should be preserved, and roboethics can help to define the framework and standards for the use of robots in medical practice.
THEORETICAL BASIS OF INFORMATION AND COMMUNICATION SUPPORT OF HEALTHCARE ACTIVITIES
Authors: RUDNICHENKO YE. , HAVLOVSKA N. , KRYMCHAK L. , TOMASHCHUK M. , LISOVSKYI І. ,   Khmelnytskyi National University
Published: December 2023

The article investigates the theoretical essence of information and communication support of health care institutions, analyzes its components such as information and communication. The main approaches to the interpretation of the concept of “information” from the point of view of different branches of science are revealed. The paper identifies that health care facilities are in continuous communicative interaction with the target audience – government agencies, the public, the population, and schematically presents its process. It is determined that the health care sector is characterized by the presence of internal and external information environments, within which internal and external communication links are distinguished and implemented. It is noted that the management of information and communication support of health care institutions provides for the functioning of a single information system of the institution, which is part of the national medical information system. The article analyzes the functional components of information and communication support of medical institutions and presents their brief characteristics. The functional components of the work include: information support, communication, organizational, legal, financial, software, mathematical, technological and documentary support. It was found that the management of information and communication support of the health care institution involves the allocation of two subsystems: information and communication. Management of the information subsystem offers the organization of work from information arrays, management of the communicative system of connection to establishment of communicative communication with target auditors. The article establishes generalized principles of functioning and development of the system of information and communication support of health care institutions. It is determined that the management of health care facilities directly depends on the development and use of modern technologies, which contributes to the improvement of the management process.
The Effect of Extensive Reading Strategy on Students’ Reading Comprehension at Smp Dharma Wanita In The Academic Year Of 2023/2024
Authors: Prayuda Meikardo Samuel , Ginting Fiber Yun A , Dila Afrilia
Published: December 2023

The objectives of this study is to find out whether extensive reading give significant effect to the students’ reading comprehension. The method in this research was Experimental research. This research had been conducted at SMP Dharma Wanita. The Population of this research was the eighth grade students of SMP Dharma Wanita which consisted of 48 students into two classes, namely VIII-A and VIII-B. VIII-A as the experimental class and VIII-B as the control class. Both of classes consisted of 48 students with homogenous score. The experimental class treated by using extensive reading strategy, while the control class was using the conventional ways. The pre-test was given to the two groups before giving the treatment. The result of pre-test showed the mean score of experimental class was 40,16 and the control class was 36,35. After giving the treatment, post-test was given. The result of post-test showed the mean score of experimental class was 72,64 and the control class was 39,65. The value of t-test was higher than the ratio on t-table (11,424>1,678). Therefore, Ho was rejected and Ha was accepted. In conclusion, Extensive Reading Strategy can be effectively to be used to teach reading comprehension of eighth grade students of SMP Dharma Wanita.
O strukturi izbornika u Ličko-krbavskoj županiji uoči Prvoga svjetskog rata
Authors: Matković Stjepan
Published: December 2023

Autor se bavi popisima izbornika na području Ličko-krbavske županije. Analiza obuhvaća razdoblje izborne reforme iz svibnja 1910. godine kojom je u znatnijoj mjeri povećan broj građana s izbornim pravom. Ličko-krbavska županija sastojala se od deset izbornih jedinica, uključujući gradove Senj i Karlobag u Hrvatskom primorju te osam izbornih kotara u Lici. S obzirom na imovinsko-porezni cenzus, koji je bio temelj izbornoga prava, može se utvrditi da je ta županija bila prepoznatljiva po najmanjem broju izbornika u odnosu na ostale hrvatske županije. U uvodnom dijelu teksta donose se usto podatci o izbornim rezultatima do reforme 1910. s naglaskom na prethodne izbore iz 1908. te se ističu teme o kojima se najviše raspravljalo oko utjecaja izborne geometrije. Izneseni su brojidbeni pokazatelji o broju izbornika Ličko-krbavske županije i na kraju analizirani rezultati saborskih izbora iz listopada 1910. na tom području.
Impact of green technology on content of bioactive components in eggplant
Authors: Martirosyan Gayane , Sarikyan Karine , Adjemyan Gohar , Pahlevanyan Armenuhi , Kirakosyan Gohar , Zadayan Merujan , Avagyan Alvina
Published: December 2023

Background: Green manure fertilizers play a great role in increasing fertility, soil quality and nutrient supply of crops. Additionally, biofertilizers with various strains of fungi increase the availability of biologically active elements for plants. The combined use of green manure and biological fertilizers is of great interest for increasing the content of bioactive components and the functional activity of food.Objective: The main goal of the research was to evaluate the effectiveness of the combined use of various green manure plants and biological fertilizers on the content of bioactive components (total sugars, dry matter, ascorbic acid, B vitamins and macro and micronutrients) in eggplants in the context of increasing food functionality. Methods: Plants from the Fabaceae L. family (beans, peas, and soybeans) were used as green manure.  The experiment was set up by a block-randomized method in 4 replications. Biofertilizers were applied at the beginning of intensive growth and at the beginning of the fruiting stage.  Soil analysis and content of macro- and micronutrients (Potassium, Calcium, Magnesium, Phosphate, and Iron) in eggplant fruits were done with a spectrophotometry system. Results:  Green manure crops and their combination with biofertilizers contributed to an increase in content of vitamin C, Vitamin B1, macro-micronutrients (calcium, potassium, phosphorus, magnesium, and Iron) in all treatment options. The higher yield was recorded in variants with the use of Organit N’ and ‘Organit P’.Conclusion: The concurrent application of green manure and biofertilizers leads to an enhancement of the functional properties of eggplant fruits. This improvement is attributed to the enhanced soil quality and increased levels of nutrients and bioactive compounds, including vitamins C and B1.The positive effect of the applied technology on the eggplant fruits’ qualitative particularities, productivity and functionality creates a basis for recommending the use of tested fertilizers to producers and will serve as a starting point for evaluating the proposed green technology on other crops.Keywords: soya, bean, pea, vitamin C, vitamin B 1
FORMATION OF A MODERN MUSEUM IMAGE (ON THE EXAMPLE OF THE STATE ART MUSEUM OF THE ALTAI KRAI)
Authors:   Altai State Institute of Culture, Shakhovalova E. G. , Tsaregorodtseva D. M. ,   Altai State Institute of Culture
Published: December 2023

The formation and development of a positive image of a museum institution in modern socio-cultural conditions is a key aspect of the museum's development strategy. Using the example of the State Art Museum of the Altai Krai (SAMAK), the experience of forming and strengthening the positive image of a museum institution is considered. The authors identify current trends in the formation of the image of a modern museum, present the stages of its formation, such as: identification of the image of the museum; positioning of the museum, highlighting its strengths, from the point of view of the requirements of target groups; development, adoption of the project and implementation of an advertising strategy to create an informed image. The article discusses modern ways of promoting the image of the SAMAK: PR, advertising, mythodesign, branding. According to the authors, one of the effective tools for creating a positive image of the museum is the development and implementation of innovative projects. The paper describes the innovative project "Painting Aromatherapy", which involves the creation of perfumes for paintings by famous artists. The presentation of perfumes for paintings will become a new trend for the Museum, which will attract visitors and perceive the museum's exhibition space in a new way, will contribute to the successful promotion of the image at the regional level, contribute to the formation of a competitive identity of the institution, and ensure the effective development of the museum in the external environment.
EXPRESSIVE LOVE VOCABULARY IN THE LETTERS OF TATIANA AND ONEGIN
Authors:   University of Public Safety of the Republic of Uzbekistan, Ataeva Ranusha , Egamberdieva Guzal ,   University of Public Safety of the Republic of Uzbekistan
Published: December 2023

The crucial aspect of constructing a fictional text lies in identifying linguistic clichés and speech patterns that reflect the speaker’s thinking, behaviour, and cultural background. This is particularly important when exploring the love theme description in A.S. Pushkin’s novel “Eugene Onegin” and examining expressive and semantic speech mechanisms. The research aims to consider the techniques of using expressive language units of love context in the letters of the novel “Eugene Onegin”. The research offers novel insights into the extensive use of love vocabulary and illogical thematic organization in Onegin’s letter, providing a contrasting expressive context and character portrayal. It highlights the absence of letter etiquette and explores the significance of love letters in fiction. To achieve the research objectives, various methods, such as descriptive, content analysis, and comparative approaches, were employed. The research findings highlighted that comprehending linguistic clichés and speech standards, specifically their semantics and expressive nature, is essential for readers to grasp and fully immerse themselves in the depicted reality within the text. The love lexicon of the textual letters of the characters in A.S. Pushkin’s novel “Eugene Onegin” is no longer one of the elements reproduced and quoted in the text, but has become an important structural tool for describing the theme of love in the fiction text. The significance of the linguistic organization of the fragments representing the letters of Tatiana and Onegin is noted by Pushkin already at the level of the way they are included in the overall text. These ways include the introduction of the letters by a separate title, provided that neither chapters nor stanzas of the novel have titles, as well as the presence of special segments of text in the lyrical digressions, indicating a certain singularity of the letters. In addition, it has been determined that in the novel the synthesis of love vocabulary and expression has been developed in a linguistic-genre context of a higher level: the novel is permeated with the properties of lyrical poetry. In the composition of the text, such properties have found a clear form in the two most representative speech genres: in the love letter and the author’s multi-thematic and multidimensional reflections on love in the lyrical digressions. The practical significance lies in the use of the research results by scholars, as well as specialists in the field of linguistics and literary studies.
Analysis of studies of stationary tower cranes under wind loads
Authors: Gorbatyuk Ievgenii , Mishchuk Dmitry , Bulavka Oleg , Voliyanuk Volodymer
Published: December 2023

Loading and unloading operations are an integral part of the technological process of construction. Cranes of various types are mostly used to perform these works.

In modern industrial and civil construction, tower cranes of the stationary type are widely used, which are used in the construction of various types of structures and buildings.

Today, it is impossible to imagine a panorama of a city or a fairly large rural village without the upward, light openwork silhouettes of tower cranes. They are clearly visible against the background of new residential buildings, wherever progressive changes are taking place, where construction is underway. More than 200,000 tower cranes are used on construction sites in the country today.

But when using tower cranes, special attention must be paid to their operation in adverse conditions, because they are mechanisms of increased danger.

One of the important factors in the unfavorable conditions during the full-scale Russian invasion of Ukraine was the shock waves that arise as a result of missile strikes. These shock waves, in turn, cause air pressure and oscillations on the Earth's surface and cause certain seismicity.

To ensure trouble-free operation and increase the reliability of tower cranes, it is important to take into account dynamic loads, which are several times greater than static loads, when calculating structures and components of their working equipment.

Ensuring the stability of stationary tower cranes, especially in the conditions of martial law, is one of the important theoretical and practical tasks. The most important aspect of solving this problem is ensuring stability under the conditions of air shock waves, which cause the effect of dynamic loads on the metal structures of the crane.
Validación de la escala de comunicación materna sobre salud sexual
Authors: Rosales Piña Consuelo Rubi , Sánchez Medina Ricardo , Enríquez Negrete David Javier
Published: December 2023

La comunicación entre padres e hijos es fundamental y ha demostrado ser un predictor en conductas protectoras o de riesgo en diferentes ámbitos de la vida de los hijos, si bien existen instrumentos que la valoran, no se cuenta con instrumentos culturalmente válidos y confiables que permitan conocer qué hablan y cómo perciben la comunicación que tienen con su madre, hombres que tienen sexo con hombres sobre salud sexual. Por lo que el objetivo de la presente investigación fue validar la escala de comunicación sexual materna en hombres que tienen sexo con hombres. Participaron 219 jóvenes solteros con una edad promedio de 21 años, que acuden a una clínica especializa en atención de VIH, de los cuales el 64.7% reporta identificarse como homosexual, todos mencionaron vivir con su madre. Se aplicó de forma individual la escala de comunicación materna sobre salud sexual (ECM-SS) conformada por 14 reactivos en formato tipo Likert con cinco opciones de respuesta. Para cada uno de los reactivos se realizó un análisis descriptivo, además se obtuvo el análisis factorial exploratorio y confirmatorio, así como la consistencia interna (ω de McDonald). De acuerdo con el análisis factorial exploratorio, la escala quedo conformada por 14 reactivos agrupados en dos factores, el primero con ocho y el segundo con seis reactivos, con una varianza total explicada de 76.6. El análisis factorial confirmatorio se ajustó en el segundo modelo obteniendo los siguientes valores de ajuste x2=196, p<.001, CFI=0.9, RMSEA=.08, por último se obtuvo ω=.90 para cada factor. Las propiedades psicométricas de la escala son adecuadas, se sugiere ampliar la evidencia en muestras similares, que permitan utilizar dicha escala en la evaluación de la comunicación materna sobre salud sexual, para promover conductas sexuales protectoras.
The dynamic market for short-cycle higher education programs
Authors: Carranza Juan Esteban , Ferreyra María Marta , Gazmuri Ana Maria
Published: December 2023

We investigate the entry and exit of short-cycle higher education programs (SCPs), which last two or three years and can address local skill needs. Exploiting administrative data from Colombia, we study markets defined by geographic location and field of study. We find that institutions open new programs in response to local labor market demand, competition, and costs. Within markets, they often close and open programs simultaneously, possibly due to capacity constraints. SCPs are more responsive to local labor market demand than bachelor’s programs; private and non-university SCP providers are the most responsive. These findings have implications for workforce development.
Simulation modeling of the strategic development of the higher education system of the Russian Federation
Authors: Kuznetsova Yu. A.
Published: December 2023

Global trends and current problems of the Russian higher education system determine the relevance of the tasks of analyzing and forecasting the long-term development of the Russian higher education system and developing management decisions aimed at its improvement. These tasks can be solved with the help of computer models of the education system, which allow us to study the behavior of a complex system in dynamics, considering the interactions of its elements, lag effects, and feedback loops. Despite the ongoing research in this area, the issue of management decision support tools for the strategic development of the Russian higher education system has not been resolved.

The article discusses the issues of simulation modeling of the higher education system of the Russian Federation, considering its interaction with macroeconomic and demographic factors. The proposed set of simulation models of the higher education system is developed using agent-based modeling and system dynamics methods. The functioning of the education system is described at different levels in the proposed set of models: the individual level, the educational institutions level, and the macroeconomic level. The set of models can be used as the basis for tools to support strategic planning of the Russian Federation’s education system development.
Developing typical profiles of generation Z students to improve the quality of the educational process
Authors: Lerner I. M. , Baykov F. Yu. , Karelina E. A. , Grigoriev S. G. , Sychev A. S. , Dymkova S. S.
Published: December 2023

Global digital platforms that influence the development of local digital platforms (from national-level platforms to the platform of a particular enterprise), in order to be more effective, must take into account the informational requirements of users, including those determined by their emotional and psychological characteristics. For this purpose, their developers need to know the typical emotional and psychological profiles of users.

The construction of typical emotional and psychological profiles of Generation Z learners is necessary for correct and efficient operation of information and educational platforms, in particular, adaptive e-learning environments, which, among other things, implement gamification approaches.

To identify the above-mentioned profiles of Generation Z learners, we use R. Cattell’s multifactor testing methodology (form C) and subsequent processing of the obtained results using statistical methods (in the form of cluster analysis). To ensure the representativeness of the results, the study involved 994 students from various universities (the survey results were used in an impersonal form).

The analysis of clustering results makes it possible to identify the share of students who are able to independently form new knowledge and obtain original results of intellectual activity, to determine the share of students with a pragmatic attitude to life, as well as those who possess the qualities of business leadership, etc.

Based on these results, recommendations for improving the quality of the educational process as a special case of adaptive e-learning environment are formulated.
Smart dictionary application for learning foreign languages
Authors: Goncharova O. N. , Goncharov A. M.
Published: December 2023

The primary composition and the further enhancement of the vocabulary of a foreign language are essential constituents of learning techniques. This segment of language learning is quantitatively and qualitatively underrepresented by electronic services, thus, the development of a new contemporary vocabulary enhancement service is reasonable. The article aims to elaborate and describe a new architectural model of such an application, which will solve present issues and introduce several novel techniques.

To create the model, a comparative analysis of existing applications, their classification, and the study of the main pedagogical concepts applied in their construction were carried out. The model is based on the peculiarities of human approaches to memorizing linguistic constructions of foreign languages. An application based on the model was implemented.

The software product can be utilized in the process of teaching the discipline “Foreign Language” at all levels of general and professional education. To analyze the effectiveness of the new service, compliance with the requirements of a user-centered vocabulary app and assess the usability of the interface, a survey was conducted. Based on its results, it can be concluded that the built application provides a simple and effective tool to fill one of the gaps in the skills of foreign language learners.
Lessons learned in medical students’ remote social responsibility experiences during COVID-19 pandemic
Authors: Demirören Meral , Atılgan Bürge , Aslan Dilek
Published: December 2023

Background: With the declaration of the COVID-19 pandemic in March 2020, face-to-face medical education was interrupted. To make first-year students a part of the fight against the pandemic, “We, as well, are in the Fight Against Novel Coronavirus Disease (COVID-19)!” remote social responsibility project was implemented in May 2020.
Aim: The aim of the study was to evaluate the perceptions and opinions of medical students regarding their remote social responsibility experiences during the COVID-19 pandemic.
Methods: Thematic content analysis of short-written reflection data collected to provide a deep insight into the experiences of the medical students was carried out. Results: The meaning and achievements of the remote social responsibility project revealed seven themes: “perception of social responsibility”, “perception of being medical students”, “perception of being a physician”, “fight against the pandemic”, “affective achievements”, “acquisition of generic skills” and “corporate commitment”. The findings draw attention to understanding the meaning of social responsibility, medical students’ and physicians’ role and responsibility in protecting health during the pandemic.
Conclusion: Medical students providing social responsibility opportunities for their students during the pandemic enables them to be a part of the fight against the pandemic and ensure important gains. These gains also valuable in preparing them for pandemics and similar emergencies in their future professional lives. In addition, competencies such as communication in crisis environment, access to evidence-based information, informing the society that will prepare for crisis situations should be gained in the medical education.