bluuebunny/crossref_metadata_2025 huggingface dataset:
Metabolic infant nephropathies: a systematic review
Authors: Burlutskaya A. V. , Kovalenko N. S. , Statova A. V.
Published: April 2021

Background. Metabolic diseases are growing, also in paediatric practice. Metabolic nephropathy is becoming more prevalent comprising 27–64% total paediatric nephrological cases, according to various published evidence. In this concern, the correct diagnosis, dietary and drug therapy acquire particular importance.

Objectives. An overview of current methods for laboratory and instrumental diagnosis and treatment of metabolic nephropathies in children.

Methods. National and foreign literature sources were mined in the RSCI, VAK, Scopus, Web of Science, PubMed, Cochrane Library and eLibrary databases at a search depth limited to seven years. The query keywords were: metabolic nephropathy [обменная нефропатия], children [дети], calcium oxalate crystalluria [оксалатно-кальциевая кристаллурия], therapy [терапия]. Content and descriptive analyses were used as research tools.

Results. The review surveyed 74 literature sources, with 50 selected for further analysis.

Discussion. Modern views on metabolic nephropathies are highlighted in terms of classification, clinical progression, methods of diagnosis, treatment and prevention. A current trend in these diseases is earlier-age morbidity. The most studied metabolic nephropathy is calcium oxalate crystalluria. The article also discusses the role of Oxalobacter formigenes bacteria in secondary oxalate nephropathy.

Conclusion. Therapies for metabolic nephropathies as polyaetiologic diseases are multicomponent to target both a causal factor and lithogenesis-contributing mechanisms. Current treatment approaches to metabolic nephropathies in children are highlighted in the light of published knowledge.
Dorsal epidural “Spindle Cell Lipoma” in a pregnant female
Authors: di Norcia Valerio , Berra Luigi Valentino , D’Angelo Luca , Santoro Antonio
Published: April 2021

Background:

Spindle cell lipoma (SCL) constitutes just 1.5% of all lipomatous tumors. They typically occur in the upper back and shoulders. Here, we report a 37-year-old female presenting with a SCL in the dorsal epidural thoracic spine, during her 9th month of pregnancy.

Case Description:

A 37-year-old female presented with a subacute (2 months) progressive paraparesis during her 9th month of pregnancy. The MR showed a dorsal epidural mass at the D8 level. Following a cesarean section, the patient underwent a laminectomy for tumor excision. Microscopically, the lesion proved to be a SCL. At 5-year follow-up, there was no tumor recurrence.

Conclusion:

SCL represents a variant of benign lipomas that may occur in the dorsal thoracic spine. Gross total excision may be followed by a benign clinical course without recurrence or malignant degeneration. Very atypical SCLs need closer follow-up to avoid the misdiagnosis of liposarcoma.
Pemanfaatan Tenaga Surya Untuk Lampu Jalan Solar Cell di Kawasan Lab.Terpadu UNIPMA Sebagai Penerapan Matakuliah EBT Berbasis Proyek
Authors: Juliana Iman Rizky , Sunaryantiningsih Ina
Published: April 2021

Artikel ini disusun berdasarkan pembelajaran berbasis proyek pada mata kuliah Energi terbarukan yang diaplikasikan pada Lampu Penerangan Solar Cell pada kawasan Lab.terpadu UNIPMA. Pembelajaran berbasis proyek selaian sebagai cara belajar memcahkan masalah yang timbul juga merupakan cara  memotivasi mahasiswa untuk meningkatkan rasa percaya diri, berkolaborasi dengan tim serta dapat bertanggung jawab untuk menyelesaikan suatu proyek secara kelompok atau tim. Pemanfaatan lampu jalan solar cell sebagai penerangan kawasan Lab.terpadu dengan menggunakan komponen lampu dc 40 watt input dengan tegangan Vdc, dengan viewing engle 120o  dengan panel surya Monocrystalline 60 watt. Dengan sistem penerangan otomatis menggunakan sensor microwave dan dimer.
Home dialysis in french speaking countries in 2020 (RDPLF database)
Authors: Verger Christian , Veniez Ghislaine , Padernoz Marie-Christine , Fabre Emmanuel
Published: April 2021

The RDPLF collects the main peritoneal dialysis data from centers in French-speaking countires and, since 2012, home hemodialysis (HHD) data. This article presents a summary of the main results in the RDPLF in 2020. It highlights important differences in the practices and patient profiles between French-speaking countries. Mortality in patients with clinical symptoms of COVID-19 varied from 15 to 63% depending on the country. A slight drop in the incidence rate for peritoneal dialysis in 2020 was observed when the Covid-19 pandemic should have favored a dialysis treatment at home. In patients with HHD, daily hemodialysis five days a week, at a low flow rate of dialysate, is predominant in the new centers and sometimes begins to appear as a mode of transition which allows to maintain at home patients who cannot anymore be treated by PD. In HHD, the use of a central catheter is frequent in Belgium while this is exceptional in France. Likewise, in France, puncture of an arteriovenous fistula remains classic, while in Belgium the Buttonhole technique is widely preferred. We did not observe COVID-19 mortality in HHD in 2020 but only 47% of HDD patients are included in the RDPLF while 98% of PD patients are included.
Mechanism of the Arene-Limited Nondirected C–H Activation of Arenes with Palladium
Authors: Wedi Philipp , Farizyan Mirxan , Bergander Klaus , Mück-Lichtenfeld Christian , van Gemmeren Manuel
Published: April 2021

Recently palladium catalysts have been discovered that enable the directing group-free C–H activation of arenes without requiring an excess of the arene substrate, thereby enabling methods for the late-stage modification of complex organic molecules. The key to success has been the use of two complementary ligands, an N-acyl amino acid and an N-heterocycle. Detailed experimental and computational mechanistic studies on the dual ligand-enabled C–H activation of arenes have led us to identify the catalytically active species and a transition state model that explains the exceptional activity and selectivity of these catalysts. These findings are expected to be highly useful for further method development using this powerful class of catalysts.
Origin of Enantioselectivity Reversal in Lewis Acid-Catalysed Michael Additions Relying on the Same Chiral Source
Authors: Riehl Paul S. , Richardson Alistair D. , Sakamoto Tatsuhiro , Reid Jolene P. , Schindler Corinna
Published: April 2021

Enantiodivergence is an important concept in asymmetric catalysis that enables access to both enantiomers of a product relying on the same chiral source as reagent. This strategy is particularly appealing as an alternate approach when only one enantiomer of the required chiral ligand is readily accessible but both enantiomers of the product are desired. Despite the potential significance, general catalytic methods to effectively reverse enantioselectivity by changing an achiral reaction parameter remain underdeveloped. Herein we report our studies focused on elucidating the origin of metal-controlled enantioselectivity reversal in Lewis acid-catalysed Michael additions. Rigorous experimental and computational investigations reveal that specific interactions between the substrate and ligand depending on the choice of metal catalyst are a key factor responsible for the observed enantiodivergence. This holds potential to further our understanding of and facilitate the design of future enantiodivergent transformations.
Rational Design and Identification of Harmine-Inspired, N-Heterocyclic DYRK1A Inhibitors Employing a Functional Genomic in vivo Drosophila Model System
Authors: Ashfeld Brandon , Huizar Francisco , Hill Harrison , Zartman Jeremiah , Bacher Emily , Eckert Kaitlyn , Gulotty Eva , Tucker Zachary , Wiest Olaf , Rodriguez Kevin X.
Published: April 2021

Deregulation of dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) plays a significant role in developmental brain defects, early-onset neurodegeneration, neuronal cell loss, and dementia. Herein, we report the discovery of three new classes of N-heterocyclic DYRK1A inhibitors based on the potent, yet toxic kinase inhibitors, harmine and harmol. An initial in vitro evaluation of the small molecule collection assembled revealed that the core heterocyclic motifs benzofuranones, oxindoles, and pyrrolones, showed statistically significant DYRK1A inhibition. Further, the utilization of a low cost, high-throughput functional genomic in vivo model system to identify small molecule inhibitors that normalize DYRK1A overexpression phenotypes is described. This in vivo assay confirmed the in vitro results, and the resulting correspondence validates generated classes as architectural motifs that serve as potential DYRK1A inhibitors. Further expansion and analysis of these core compound structures will allow discovery of safe, more effective chemical inhibitors of DYRK1A to ameliorate phenotypes caused by DYRK1A overexpression.
Uncertainty-Informed Deep Transfer Learning of PFAS Toxicity
Authors: Feinstein Jeremy , sivaraman ganesh , Picel Kurt , Peters Brian , Vazquez-Mayagoitia Alvaro , Ramanathan Arvind , MacDonell Margaret , Foster Ian , Yan Eugene
Published: April 2021

In this article, we present our recent study on computational methodology for predicting the toxicity of PFAS known as “forever chemicals” based on chemical structures through evaluation of multiple machine learning methods. To address the scarcity of PFAS toxicity data, a deep “transfer learning” method has been investigated by leveraging toxicity information over the entire organic chemical domain and an uncertainty-informed workflow by incorporating SelectiveNet architecture, which can support future guidance of high throughput screening with knowledge of chemical structures, has been developed.
Fluorescent Nanodiamonds Encapsulated by Cowpea Chlorotic Mottle Virus (CCMV) Proteins for Intracellular 3D-Trajectory Analysis
Authors: Wu Yingke , Cao Shuqin , Alam Md Noor A , Raabe Marco , Michel-Souzy Sandra , Wang Zuyuan , Wagner Manfred , Ermakova Anna , Cornelissen Jeroen J. L. M. , Weil Tanja
Published: April 2021

Long-term tracking of nanoparticles to resolve intracellular structures and motions is essential to elucidate fundamental parameters as well as transport processes within living cells. Fluorescent nanodiamond (ND) emitters provide cell compatibility and very high photostability. However, high stability, biocompatibility, and cellular uptake of these fluorescent NDs under physiological conditions are required for intracellular applications. Herein, highly stable NDs encapsulated with Cowpea chlorotic mottle virus capsid proteins (ND-CP) are prepared. A thin capsid protein layer is obtained around the NDs, which imparts reactive groups and high colloidal stability, while retaining the opto-magnetic properties of the coated NDs as well as the secondary structure of CPs adsorbed on the surface of NDs. In addition, the ND-CP shows excellent biocompatibility both in vitro and in vivo. Long-term 3D trajectories of the ND-CP with fine spatiotemporal resolutions are recorded; their intracellular motions are analyzed by different models, and the diffusion coefficient are calculated. The ND-CP with its brilliant optical properties and stability under physiological conditions provides us with a new tool to advance the understanding of cell biology, e.g., endocytosis, exocytosis, and active transport processes in living cells as well as intracellular dynamic parameters.
Diversification of 4ʹ-Methylated Nucleosides by Nucleoside Phosphorylases
Authors: Kaspar Felix , Seeger Margarita , Westarp Sarah , Köllmann Christoph , Lehmann Anna P. , Pausch Patrick , Kemper Sebastian , Neubauer Peter , Bange Gert , Schallmey Anett , Werz Daniel , Kurreck Anke
Published: April 2021

The growing demand for 4'-modified nucleoside analogs in medicinal and biological chemistry is contrasted by the challenging synthetic access to these molecules and the lack of efficient diversification strategies. Herein, we report the development of a biocatalytic diversification approach based on nucleoside phosphorylases, which allows the straightforward installation of a variety of pyrimidine and purine nucleobases on a 4'-alkylated sugar scaffold. Following the identification of a suitable biocatalyst as well as its characterization with kinetic experiments and docking studies, we systematically explored the equilibrium thermodynamics of this reaction system to enable rational yield prediction in transglycosylation reactions via principles of thermodynamic control.
On the Mechanism of Electrochemical Generation and Decomposition of Phthalimide N-oxyl (PINO)
Authors: Yang Cheng , Farmer Luke , Pratt Derek , Maldonado Stephen , Stephenson Corey
Published: April 2021

Phthalimide N-oxyl (PINO) is a potent hydrogen atom transfer (HAT) catalyst that can be generated electrochemically from N-hydroxyphthalimide (NHPI). However, catalyst decomposition has limited its application. This paper details mechanistic studies of the generation and decomposition of PINO under electrochemical conditions. Voltammetric data, observations from bulk electrolysis, and computational studies suggest two primary aspects. First, base-promoted formation of PINO from NHPI occurs via multiple-site concerted proton-electron transfer (MS-CPET). Second, PINO decomposition occurs by at least two second-order paths, one of which is greatly enhanced by base. Optimal catalytic efficiency in PINO-catalyzed oxidations occurs in the presence of bases whose corresponding conjugate acids have pKas in the range of 12-15, which strike a balance between promoting PINO formation and minimizing its decay.
Preparation of a Rigid and nearly Coplanar Bis-Tetracene Dimer through Application of the CANAL Reaction
Authors: Miller Ethan G. , Singh Madhu , Parkin Sean R. , Sammakia Tarek , Damrauer Niels
Published: April 2021

A rigid tetracene dimer with a substantial interchromophore distance has been prepared through the application of the recently developed catalytic arene-norbornene annulation (CANAL) reaction. An iterative cycloaddition route was found to be unsuccessful, and so a shorter route was adopted whereby fragments were coupled in the penultimate step to form 13 : 1 mixture of two diastereomers, the major of which was isolated and crystallized. Constituent tetracene moieties are linked with a rigid, well-defined bridge, and feature a near co-planar mutual orientation of the acenes.
Tracking Structure and Composition Changes in Oxide Derived Cu-Sn Catalysts During CO2 Electroreduction Using X-Ray Spectroscopy
Authors: Pardo Pérez Laura C. , Arndt Alexander , Stojkovikj Sasho , Ahmet Ibbi Y. , Davies Veronica , Höflich Katja , Köhnen Eike , Tockhorn Philipp , Golnak Ronny , Xiao Jie , Schuck Götz , Mayer Matthew
Published: April 2021

In the field of electrochemical CO2 conversion, the development of earth-abundant catalysts which are selective for a single product is a central challenge. Cu-Sn bimetallic catalysts have been reported to yield selective CO2 reduction towards either carbon monoxide or formate. To advance the understanding of possible synergetic effects between Cu and Sn which direct product selectivity, a thorough investigation of the catalyst structure and composition in its active state is desired. We present an X-ray spectroscopy investigation of oxide-derived Cu-Sn catalysts prepared by functionalization of Cu(OH)2 nanowire arrays with ultrathin SnO2 overlayers. This method allows precisely tunable Sn composition, which enables synthesis of composite catalysts with high selectivity toward either CO or formate. Under CO2 reduction conditions, the materials undergo significant transformations before reaching their catalytically active forms. Complementary information on the electrocatalysts’ dynamic bulk and surface structure was revealed via correlating observations from multiple X-ray spectroscopy methods. In situ investigations of Cu K-edge revealed that in the bulk Cu is fully reduced from Cu2+ to Cu° after a pre reduction step. Quasi in situ XPS demonstrated that, at the catalyst surface, Cu is also present exclusively as Cu°, whereas significant differences in Sn quantification and speciation were observed between the CO- and formate-selective catalysts. After CO2 electrolysis, CO-selective catalysts exhibited a surface Sn content of 13 at. % predominantly present as Sn oxide, while the formate-selective catalysts had a Sn content of ~70 at. % consisting of both metallic Sn° and Sn oxide species. Our study reveals the complex dependence of catalyst structure, composition, and speciation with applied electrochemical bias in Sn-functionalized nanostructured Cu catalysts.
Labeling and Probing the Silica Surface Using Mechanochemistry and 17O NMR Spectroscopy
Authors: Chen Chia-Hsin , Mentink-Vigier Frederic , Trébosc Julien , Goldberga Ieva , Gaveau Philippe , Thomassot Emilie , Iuga Dinu , Smith Mark E. , Chen Kuizhi , Gan Zhehong , Fabrègue Nicolas , Métro Thomas-Xavier , Alonso Bruno , Laurencin Danielle
Published: April 2021

In recent years, there has been increasing interest in developing cost-efficient, fast, and user-friendly 17O enrichment protocols to help understand the structure and reactivity of materials using 17O NMR. Here, we show for the first time how ball milling (BM) can be used to selectively and efficiently enrich the surface of fumed silica, which is widely used at the industrial scale. Short milling times (up to 15 min) allowed modulation of the enrichment level (up to ca. 5%) without significantly changing the nature of the material. High-precision 17O-compositions were measured at different milling times using LG-SIMS. High-resolution 17O NMR analyses (including at 35.2 T) allowed clear identification of the signals from siloxane (Si-O-Si) and silanols (Si-OH), while DNP analyses, performed using direct 17O polarization and indirect 17O{1H} CP excitation, agreed with selective labeling of the surface. Information on the distribution of Si-OH environments at the surface was obtained from 2D 1H-17O D-HMQC correlations. Finally, the surface-labeled silica was reacted with titania and using 17O DNP, their common interface was probed and Si-O-Ti bonds identified.
Run-and-Halt Behavior of Motile Droplets in Response to Light
Authors: Ryabchun Alexander , Babu Dhanya , Movilli Jacopo , Plamont Rémi , Katsonis Nathalie
Published: April 2021

We report the run-and-halt behavior of motile droplets immersed in an aqueous solution of amphiphilic molecular switch. These oil droplets move autonomously as the switch solubilizes the oil into the water. Droplet movement stops in response to UV light, and picks up again in response to visible light. This motile behavior is a consequence of the reversible trans-to-cis photo-conversion of the switch in water, because the trans photo-isomer stabilizes the oil droplets better than the cis photo-isomer, and therefore it also solubilizes the droplet more effectively. Notably, the droplets also evolve positive photokinesis under illumination with visible light, and, in patchy light environments, their complex motility pattern directs the droplets at the periphery of the illuminated areas.
Thermoelectric Properties of the As/P-Based Zintl Compounds EuIn2As2−xPx (X = 0 to 2) and SrSn2As2
Authors: Shinozaki Keisuke , Goto Yosuke , Hoshi Kazuhisa , Kiyama Ryosuke , Nakamura Naoto , miura akira , Moriyoshi Chikako , Kuroiwa Yoshihiro , Usui Hidetomo , Mizuguchi Yoshikazu
Published: April 2021

Zintl compounds containing Sb have been studied extensively because of their promising thermoelectric properties. In this study, we prepared As/P-based Zintl compounds, EuIn2As2-xPx (x = 0 to 2) and SrSn2As2, and examined their potential for use as thermoelectric materials. These compounds show hole carrier concentrations of ~10^19 /cm3 for EuIn2As2-xPx and ~10^21 /cm3 for SrSn2As2 at 300 K. The high carrier concentration of SrSn2As2 is likely owing to self-doping by hole-donating Sn vacancies. The electrical power factor reaches ~1 mW/mK2 at ~600 K for EuIn2As2-xPx with x = 0.1 and 0.2. The lattice thermal conductivity is determined to be 1.6–2.0 W/mK for EuIn2As2 and SrSn2As2, and 2.8 W/mK for EuIn2P2 at 673 K. The dimensionless figure of merit reaches ZT = 0.29 at 773 K for EuIn2As2-xPx with x = 0.2. First-principles calculations show that EuIn2As2 and SrSn2As2 are topologically nontrivial materials with band inversion, while EuIn2P2 is a conventional semiconductor with a bandgap. The present study demonstrates that As/P-based Zintl compounds can also show promising thermoelectric properties, thus expanding the frontier for efficient thermoelectric materials.
Computational Study of the C-H∙∙∙H-C Contacts in Valine-Methane Complexes.
Authors: Mohan Neetha , Varela-Álvarez Adrián , Ramana Chintalapalle V. , sirimulla suman
Published: April 2021

A series of complexes between neutral Valine and methane that feature potential homopolar C-H∙∙∙H-C contacts were located on the MP2/aug-cc-pVTZ potential energy hypersurface. In order to better estimate the strength of this contacts, the interaction energies were improve by single-point calculations at different levels of theory (MP2, CCSD(T), SAPT2, SAPT2+3) together with Dunning’s basis sets (aug-cc-pVXZ; X=T,Q,5). Topological analysis of the electron density within the QTAIM framework, NCI plots and energy decomposition within the SAPT framework were used to discuss the nature of this interactions. The complexes whose monomers only interact though C-H∙∙∙H-C contacts indicate that these interactions are entirely due to dispersion forces, are not directional and are much stronger than expected (the interaction energies of the complexes range from -0.7 to -1.0 kcal/mol). This large value is remarkable considering the small size of the interacting groups herein considered (methane, and one or two Valine’s methyl groups), and indicates that in biological systems, where those interactions can be very numerous in the presence of multiple aliphatic amino acids, if those interactions are not properly model, magnitudes as ligand-receptor affinities, protein-protein interaction energies and protein stabilities might be grossly misestimated. Finally, since some of the computed complexes also include stronger interactions than homopolar C-H∙∙∙H-C contacts, we analyzed if the potential C-H∙∙∙H-C contacts in these complexes are really contributing to stabilize the complexes or are just a geometrical artifact arising from the maximization of stronger interactions.
The influence of leadership behaviors on employee performance in Beijing, China hotel industry
Authors:   SEGI University, Malaysia
Published: April 2021

China has successfully held the 29th Olympic Games in Beijing. China’s hotel industry also got really booming in 2008. Variety of foreign hotel brands came into the China’s market. Developing of hotel industry need deluge of labors to support. However, many hotels have low service quality of employees, even there was occurring in high proportion of turnover. Result in one of the main reasons of poor employees’ performance is leadership behaviors; the way of leadership behaviors may directly influence employees’ performance. This study researched employees ‘performance in five stars hotels in Beijing, China, through the way of collect questionnaires to obtain original data. Collecting data adapt to questionnaire method the unit of analysis by SPSS system. This research finds that between employees’ performance, and leadership behaviors have significant relationship, because the positive of leadership behaviors are able to employees feels happy and satisfaction. Active leadership behaviors can help employees to enhance productivity, service quality, and even creation. In this research underlined affect the most reason of employee’s performance.
The study of electricity-saving behavior of personnel at Phranakhon Rajabhat University
Authors:   Phranakhon Rajabhat University, Thailand, Boonruang Rachadaporn
Published: April 2021

This research aimed to study the electricity-saving behavior of personnel at Phranakorn Rajabhat University. The samples consisted of 276 Phranakorn Rajabhat University’s personnel who worked during the academic year 2019. Multi-staged sampling techniques were used for samples selection. Data were collected by a questionnaire. Statistics employed were percentage, arithmetic mean, standard deviation, pearson product-moment correlation The research found that; information reception, attitude, and electricity-saving behavior were at high levels, whereas knowledge was at median. Relationship studies revealed that information reception, attitude, and electricity saving behavior of personnel at Phranakorn Rajabhat university were positively related in the same direction at significant level of .01.
​Investigating Knowledge Creation Processes Among The Royal Malaysian Navy (RMN) Fleet Personnel
Authors:   University of Malaya, Malaysia
Published: April 2021

This study was conducted to gauge the extent of knowledge creation within the Royal Malaysian Navy (RMN) fleet. It was due to rotational of personnel serving on board for their career progressions and personnel retired that may bring with them substantial amount of knowledge. Thus, quantitative study was conducted, taking into account of descriptive data analyzed by SPSS software with 234 respondents utilizing SECI model as the theoretical platform. Items analysis was conducted to gauge the extent. Apart from that, level and type of knowledge, mechanisms and venues for knowledge creation were identified. The results showed the extent of knowledge creation processes varied in every mode of SECI. Operational knowledge and knowledge from experiences are common within the fleet. Social media identified as the common mechanism utilized. Seminar, workshop and meeting were identified as the venues for most of the knowledge creation processes took place. Besides identifying the extent of knowledge creation processes, this study could be the platform for the fleet to identify suitable recommendation to create and capture more knowledge, to retain and to disseminate knowledge in order to improve fleet operations.
Current Research in Zakat Accounting Research
Authors:   Politeknik Sultan Abdul Halim Muadzam Shah (POLIMAS), Uyob Roslee
Published: April 2021

Zakat Accounting is part of accounting which concerned with determination and valuation of wealth and income according to the rules set by Islamic Shariah law. In Zakat Accounting it also involves recording, interpreting, presentation and disclosure of accounting information. This study presents an analysis regarding the current research in the area of Zakat Accounting using two database system which is Scopus and Google scholar. The objective of this study is to provide the current trend in Zakat Accounting using bibliometric analysis. 35 Articles has been extracted from Scopus and Google database and exported to Mendelay software to conduct bibliometric analysis. The results shows that the research in zakat accounting has been increasing and constantly publish in the number of articles since 2011 onwards. However, they are still lacks of research that has been conducted in the area of Zakat accounting. By conducting this study, we hope it will give a general picture of a research in Zakat Accounting, which is very useful in identifying the main trends, future gaps and direction of the research in the area of Zakat Accounting in the future.
​Investigating Success Factors on Employee Performance of Accommodation and Food Service Industry in Penang, Malaysia
Authors:   Universiti Malaysia Perlis, Malaysia
Published: April 2021

The accommodation and food service market in Malaysia is very active. However, inconsistent with the rapid development of the accommodation and food service industry, accommodation and food service industry generally face problems such as shortage and loss of talent, poor service quality and competition in industry. The purpose of this paper was to investigate the successful factors that affected the employee performance of accommodation and food service industry in Penang, Malaysia. The factors that examine in this paper were training, working environment, reward and leadership. Data was gathered from the employee from accommodation and food service industry in Penang, Malaysia. The research was a quantitative research method. The researcher used a sample size determination table and used cluster sampling technique to select samples to make the samples more representative. The questionnaire was consisted of two section. The five-Likert scale was used to collect the primary data and 201 responses were properly filled and returned. SPSS was used to analyze the data collected through the questionnaire. The frequency, reliability and descriptive were calculated and explained. The results showed that there was a positive correlation between all independent variables and dependent variable. It was found that the effect of the independent variables on dependent variable was 52.9%, while the remaining 47.1 were affected by factors that were not covered by this study. In this study, it also found that training and working environment have a significantly impact on employee performance, however, reward and leadership have no significant impact on employee performance. Based on the findings, the research results were discussed and recommendations are provided for managers and future research.
Green Management Strategy – An Initiative Towards Sustainable Practices
Authors:   University of Malaya, Malaysia, Abu Bakar Raida
Published: April 2021

The current efforts put on sustenance and sustainability has driven many organizations around the world to adopt environmental management practices which include all extents of green solution. While certain common tools and knowledge can be used to control, track and evaluate these green components in an interconnected element, they are generally managed on a piecemeal basis and under various management standards; and most frequently, as ad-hoc initiatives as opposed to programs. To date, pressure to practice sustainability efforts comes mainly from two main stakeholders - the management and the customers. This concept paper looks at the implementation of green management and sustainable green practices of one organization as a case study. It proposes that management has a role to play in helping to reduce negative sustainability impact. Two theories were proposed as the theoretical lens to give meaning to the research, but further research is required to support the findings of this paper.
واقع وآفاق حماية التراث الثقافي في المنطقة العربية
Authors: Belbish Fadel
Published: April 2021

حيال ثراء المخزون التراثي للمنطقة العربية، وجد أصحاب القرار بالدول المعنيّة أنفسهم أمام خيارات عديدة للحوكمة أثّر فيها عديد الإكراهات، حيث تباينت النظرة إلى التراث الثقافي بين من يرى فيه ثروة يجدر تثمينها ومن يراه تركة ثقيلة تشكّل عبئًا ماديًّا؛ لما يتطلبه من مصاريف صيانة وحماية أمنية، ومن يرى فيه عائقًا في وجه الحداثة والتدريب، كما أن كثيرًا من الممتلكات الثقافية في طريقه إلى الاندثار؛ نتيجة اصطدامه بالزحف العمراني الذي تريده السلطات أو ذلك الذي يفرضه المضاربون العقاريون المتنفذون أو الفئات الاجتماعية محدودة الدخل بإقامتها لبنايات عشوائية؛ يضاف إلى كل هذا إشكالية نهب التراث سواء أكان من قبل الأفراد أم من قبل العصابات المنظمة على المستوى الوطني أو ذات الامتداد على المستوى الدولي؛ فمسألة التراث الثقافي توجد في قلب السياسات الأمنية والثقافية والتنموية لأغلب الدول العربية، كما أنها تطرح عند قيام النزاعات المسلحة وعلاقة ذلك بأنشطة الجماعات الإرهابية، وما ينشأ عنها من مأساة تدمير أو نهب عناصر من التراث الثقافي. وتبدو محدودية الإمكانات المادية وتهميش مسألة التراث في خضم تزاحم الأولويات والتحديات التي تجابه السلطات من الأمور التي حدت من قدرتها على حمايته وعلى اقتناص الفرص التي تخولها تثمينه لغاية تحقيق تنمية مستدامة. ومن هنا نوصي أساسًا بالزيادة المهمة في الاعتمادات المالية المخصصة لحماية التراث ودعم التعاون الإقليمي والدولي في المجالات المتصلة به، مع منظمات متنوعة مثل: الشرطة الأوربية والإنتربول ومكتب الأمم المتحدة المعني بالمخدرات والجريمة؛ بالإضافة إلى التوظيف الأمثل للممتلكات الثقافية والسعي إلى إحياء مكونات التراث اللامادي التي أشرفت على الاندثار، لاسيما عن طريق الدعم المادي والتدريب وتكثيف المساعي لاسترداد التراث الثقافي المنهوب، وتولي المصادقة على الاتفاقيات الدولية التي تعنى بحماية التراث الثقافي.
الأمن البيئي
Authors: Abbas Wijdan
Published: April 2021

Environmental security is the field of interaction of environmental concerns and security strategies.
السلالات الجديدة لفيروس كورونا وانعكاساتها على الأمن الصحي
Authors: Amer Sayed
Published: April 2021

تم اكتشاف 172 سلالة جديدة نتجت عن تغيرات متنوعة في تسلسل مائة جينوم فيروسي لكوفيد-19، تمثلت في إضافة وحذف واستبدال الأحرف الوراثية للجينوم وقت انتقاله من شخص إلى آخر.
السلالات الجديدة نتجت بمعدل أعلى بمقدار150% من انتقال الفيروس بين الأفراد.
هناك احتمالان لانتقال الفيروس بين البشر أحدهما: اعتماده على التوزيع الجغرافي للتركيبة السكانية والآخر: اعتماده على مكان منشأ الفيروس، وهناك أدلة مقنعة حول المنشأ الصيني للفيروس.
أمن الحدود
Authors: Alshammari Aiyad
Published: April 2021

أمن الحدود هو المفهوم الذي يحتوى عى عدة أبعاد؛ المنع، الردع، والشبكة الاستخبارتية، وذلك للحد من التدفق غير النظامي عبر الحدود.
Security and Privacy Liability Policy in the Arab World
Authors: Kim Kyounggon
Published: April 2021

Focusing on Cooperation, Capability, and Assessment (ACC) approach performed in top-down, bottom-up, short-term, and long-term (TBSL).
Cooperation between countries is essential to proactively respond to various cyber threats such as cyber criminals and cyber terrorists and to show rapid recovery resilience.
Develop a cybersecurity evaluation model and a gap analysis model and spread them to the remaining Arab countries.
واقع سياسات الثقافة الأمنية في المؤسسات العربية في ظل جائحة «كورونا » وفرص تطويرها
Authors: Al-Mekaimi Haila
Published: April 2021

شكَّلت جائحة «كورونا » اختبارًا حقيقيًّا للمؤسسات في العالم بأسره، بما في ذلك الدول العربية؛ فقد مارست تلك الأزمة الصحية العالمية ضغطًا كبيرًا على جميع موارد الدول ومؤسساتها. وقد تباينت الدول العربية في إدارة الأزمة، حيث أبدت دول الخليج مزيدًا من القدرة والكفاءة بالمقارنة بالدول العربية الأخرى في إدارة الأزمة. وتج ذلك في سرعة التعامل مع الأزمة من حيث تأمين المخزون الغذائي والدوائي والسعي إلى الاستثمار المعرفي في الزراعة والتكنولوجيا وغيرهما الإدارة واتباع معايير الشفافية، والحوكمة، والاستقرار الاقتصادي ،والسياسي. وعلى الرغم من ذلك، تركز ورقة السياسات على فهم آليات تعزيز الثقافة الأمنية في جميع المؤسسات العربية الحكومية والخاصة عبر التعرُّف إلى مكوناتها ووضع الإستراتيجيات المتخصصة، الأمر الذي يُسهم في تعزيز قدرة الدولة على إدارة الأزمات والطوارئ، وتلك الحقيقة تؤكد أهمية الالتفات الى تعزيز الثقافة الأمنية من خلال فهم مكوناتها وعناصرها وعلاقتها بالمفاهيم الأمنية الأخرى ذات الصلة، وصولً الى وضع الأسس المهمة لتبنِّي إستراتيجيات الثقافة الأمنية الفاعلة والشاملة التي أصبحت ضمانة مهمة لأمن المجتمعات والشعوب وسلامتها.
آليات تعامل المؤسسات الإصلاحية مع انتشار الفيروسات والأوبئة
Authors: Mahmoud Sodfa
Published: April 2021

يُمثّل انتشار فيروس كورونا تحديًا خطيرًا لصحة المواطنين في مختلف أنحاء العالم، وتزداد خطورة هذا الفيروس على صحة السجناء داخل المؤسسات الإصلاحية؛ بسبب العوامل السياقية داخل تلك المؤسسات التي من بينها: الاكتظاظ، تأخر أو نقص التشخيص والعلاج، محدودية فرص الوصول إلى المياه النظيفة والهواء النقي، عدم كفاية الصرف الصحي، وهي تُسهم في زيادة خطر انتقال الفيروسات والأوبئة بين السجناء. وتزداد احتمالات انتشار الفيروسات والأوبئة داخل المؤسسات الإصلاحية أيضًا مع زيادة فرص انتقال العدوى عن طريق السجناء الوافدين، أو من خلال أسرهم وأصدقائهم وكذلك عن طريق الموظفين العاملين في تلك المؤسسات؛ بالإضافة إلى احتمال انتشارها من خلال عملية نقل السجناء من مؤسسة إصلاحية إلى أخرى. وفي ظل وجود أكثر من عشرة ملايين سجين حول العالم، يُصبح التصدي لانتشار فيروس كورونا داخل المؤسسات الإصلاحية مسألة أكثر إلحاحًا، ولذلك تسعى هذه الورقة إلى التعرف على الأسباب التي تجعل المؤسسات الإصلاحية بيئة خصبة لانتشار الأوبئة، ودراسة دوافع ضرورة العمل على منع انتشار الفيروس داخل المؤسسات الإصلاحية، واستعراض أبرز الجهود المبذولة دوليًّا وإقليميًّا للحد من انتشاره داخلها، وطرح بدائل الوقاية من الفيروس واحتواء انتشاره داخل المؤسسات الإصلاحية.
سياسات تمكين الشباب والمرأة في العالم العربي
Authors: Al Masmoudi Salim
Published: April 2021

يعدّ تمكين الشباب والمرأة  جوهر تحقيق الأمن في العالم عمومًا وفي العالم العربي خاصة، حيث إن تمكين الشباب وجعله قادرًا على أن يكون فاعلً في مجتمع القرن الحادي والعشري، ضمان لتوازن المجتمع وتطوره على مستويات عديدة، ووقاية له من الاضطرابات والانحرافات والجرائم وكل أصناف التهديدات الأمنية. وفي تمكين المرأة وجعلها قادرة على الاكتساب والكسب والمشاركة في صنع القرار، ضمان لتماسك المجتمع وتربية نشء فاعل في المجتمع وآمن من الأخطار، وضمان لقرارات، وسياسات ناجعة، ومتوازنة. ومن شأن سياسات التمكين أن تقلّص من هشاشة الشباب والمرأة ومن عوامل الأخطار لديهم، ومن شأن هذه السياسات أن تعزّز لديهم الصمود النفسي المرن وتجعلهم قادرين على مجابهة التحديات وإيجاد الحلول الملائمة  سرعة والإسهام بفاعلية في صمود المجتمع.

وتقدم هذه الورقة تحليلً لواقع الشباب والمرأة في الدول العربية حسب عدد من الأبعاد المرتبطة بتمكينهم وتتلخص في مكونات مؤشر تنمية الشباب ومؤشر الحراك الاجتماعي ومؤشرات العدالة والإنصاف بين الرجال والنساء والمؤشرات المتعلقة بالأسرة المنتجة والمنتعشة والمتعلقة بسياسات الرعاية. وعلى أساس قراءة تحليلية لهذا الواقع، تناقش الورقة الفرص والتحديات في تمكين الشباب والمرأة، وتقترح سياسات ناجحة وناجعة وممارسات جيدة توجّه السياسات العربية وتمنح صانع القرار أدوات تفكير وعمل تجعل سياساته فعّالة ومراعية لأهداف التنمية المستدامة والممارسات المثلى.
Efecto de biochar, micorrizas arbusculares y Guazuma ulmifolia, en la rehabilitación de suelos mineros
Authors: Quiroz-Mojica Laura Janeth , Daza-Mendoza María Margarita , Díaz-Muegue Luis Carlos , Melo-Rios Aslenis Emidia , Peñuela-Mesa Gustavo Antonio
Published: April 2021

La minería de carbón es una de las actividades predominantes en el departamento del Cesar, Colombia; esta impulsa el crecimiento económico del país. Después del proceso de extracción del mineral, suele utilizarse capas de suelos acopiados y material estéril para formar suelos artificiales, también llamados suelos mineros; estos, por sus condiciones edáficas poseen cierto grado de toxicidad e infertilidad, que restringe el crecimiento y la supervivencia de los organismos en el medio, dando lugar a la formación de áreas desérticas. La rehabilitación de suelos mineros fomenta el restablecimiento de las condiciones adecuadas, permitiéndole a este ofrecer nuevamente algunos bienes y servicios ambientales. El objetivo fue evaluar el efecto del biochar, los hongos formadores de micorrizas arbusculares (HMA) y NPK en la rehabilitación de suelos mineros, y en el crecimiento de la plántula Guazuma ulmifolia a partir de tres ensayos. Inicialmente se hizo un ensayo de germinación, utilizando semillas de Guazuma ulmifolia, suelos mineros y biochar en concentraciones del 0, 1, 5 y 10%; luego se estableció un ensayo a escala vivero en donde se aplicaron cuatro tratamientos que contenían a la plántula, biochar, HMA y NPK, posteriormente se realizó un ensayo a escala campo utilizando cuatro tratamientos con la plántula, biochar y HMA. Los resultados muestran que el biochar en concentraciones de 1 y 5% incrementó significativamente el porcentaje de germinación, la longitud foliar y biomasa de las plantas; además, se halló un porcentaje de infección del 60% en las raíces de la planta por HMA; así mismo, hubo un aumento importante de pH, fósforo, carbono orgánico, glomalina y actividad enzimática en los suelos, también una reducción significativa en la conductividad eléctrica. El uso de biochar y micorrizas mejoró las propiedades de los suelos y estimuló un mayor crecimiento en la plántula, promoviendo así el proceso de rehabilitación.
FAMILY MEDIATION IN COMPARATIVE KEY: ARGENTINA AND MEXICO
Authors: Franco-Castellanos Carlos , Sandoval-Salazar Rubinia Teresa
Published: April 2021

The following article, entitled: “Family Mediation in comparative key: Argentina and Mexico”, analyzed the juridical norms related to family mediation in the Chaco Province, Argentina and Nuevo Leon State, Mexico. It was used the qualitative approach, based on the study, analysis, critical view, and comparison between the legislations of both States and theoretical scientific investigations indexed in vLex, Dialnet and Scopus to ensure the accuracy of the information. It was found that the juridical design established for family mediation not only obstructs its conception as a method to access to daily justice, but also the lack of specific regulations makes difficult to work with. From the comparative study, it was concluded the necessity of introducing juridical proceedings and good practice in the familiar mediation professional activity in the Mexican juridical system, especially the conception of the mandatory prejudicial mediation in family conflicts with children involved.
CIUDAD DE CAMAGÜEY: UN DESAFÍO PARA EL USO DEL AGUA
Authors: González González Rosa
Published: April 2021

Las ciudades han tenido que afrontar múltiples retos en la búsqueda de la preservación de su patrimonio construido, al ser uno de los actuales la contaminación y el aumento de enfermedades por el mal manejo del agua. Dos son los principales desafíos en materia de agua que afectan su sostenibilidad: la falta de acceso al agua saludable y al saneamiento y el aumento de desastres relacionados con el agua como inundaciones y sequías. Estos problemas impactan negativamente en la salud y el bienestar humano, la seguridad, el medio ambiente, el crecimiento económico y el desarrollo. La falta de servicios adecuados de suministro y saneamiento, conducen a enfermedades como la diarrea o brotes de malaria y de cólera. Siendo el objetivo de la investigación valorar las causas que influyen negativamente en la contaminación de las aguas y su impacto en el bienestar de sus moradores a partir de un estudio integral que interrelacione salud y patrimonio construido, tomando como referencia la ciudad de Camagüey como caso de estudio.
Rancang Bangun Smart Trash Can Berbasis IOT (Internet Of Things) Untuk Petugas Sampah Perumahan
Authors: SAPUTRA MUH. ARDIAN , Wirarama Wedaswara I Gde Putu , Zubaidi Ariyan
Published: April 2021

Sampah merupakan hasil buangan/output dari segala aktivitas manusia. Setiap hari manusia menghasilkan sampah, baik sampah organik maupun anorganik yang memiliki berbagai bentuk dan jenis. Tidak heran permasalahan tersebut juga banyak ditemukan di lingkungan Perumahan. Salah satu perumahan yang ada di Kota Mataram adalah perumahan Babakan Permai yang terletak di kelurahan Babakan, kecamatan Sandubaya, Kota Mataram. Penanganan masalah sampah di Perumahan Babakan Permai ditangani dengan cara penjadwalan untuk pengambilan sampah pada masing-masing rumah. Sampah di ambil setiap 2 kali seminggu oleh petugas sampah perumahan. Hal ini memiliki kekurangan yaitu potensi penumpukan sampah pada tiap rumah meningkat. Penumpukan sampah sangat mengganggu warga di lingkungan sekitar baik dari segi kebersihan maupun kesehatan Dengan demikian, permasalahan tersebut dapat di atasi dengan membuat alat Smart Trash Can yang dapat mempermudah petugas sampah di perumahan. Tugas akhir ini berupa prototype tempat sampah pintar yang dapat memonitoring tempat sampah. Hal tersebut dapat dilakukan dengan menerapkan konsep IoT (Internet of Things) yang memanfaatkan internet. Protokol yang digunakan dalam IoT adalah MQTT (Message Queuing Telemetry Transport) yang bersifat lightweight message dan didesain untuk perangkat-perangkat dengan sumber daya terbatas. Dengan konsep IoT, monitoring tempat sampah dilakukan dengan menggunakan beberapa sensor seperti penggunaan sensor berat (load cell) sebagai deteksi berat sampah, modul HX711 sebagai konversi nilai berat load cell dan sensor magnetic switch untuk mengetahui bukaan/tutupan tempah sampah yang di rangkai dengan mikrokontroler.
SISTEM PENJADWALAN AIR CONDITIONER (AC) RUANGAN BERDASARKAN JADWAL MATAKULIAH MENGGUNAKAN ESP8266, PIR SENSOR DAN ANDROID
Authors: Saputra Muhammad Malik
Published: April 2021

Pada ruang lingkup Program Studi Teknik Informatika (PSTI) Universitas Mataram

(UNRAM), saat ini memiliki pengatur suhu ruangan atau biasa disebut dengan Air

Conditioner(AC) untuk menunjang kegiatan belajar mengajar namun seringkali

penggunaannya tidak terorganisir seperti membiarkan AC tetap menyala bahkan

setelah ruang kelas kosong atau tidak ada kegiatan yang menyebabkan tidak efisien

dalam menggunakan AC yang juga dapat menimbulkan kerusakan pada AC tersebut.

Oleh karena itu perlu adanya sistem yang mengontrol penjadwalan AC secara otomatis

yang lebih efisien. Hal ini dapat diwujudkan dengan teknologi Internet of Things(IoT).

Maka perlu dibangun sistem yang akan membuat AC otomatis menyala sesuai jadwal

kuliah menggunakan mikrokontroler(ESP8266 Wemos D1) dengan infrared

transmitter untuk mengendalikan AC dan deteksi gerak yang akan menggunakan

protokol MQTT sebagai broker. Sensor gerak Passive Infrared(PIR) Sensor akan

mendeteksi gerakan pada ruang kelas yang menjadi kondisi untuk mematikan AC jika

setelah 30 menit tidak ada pergerakan didalam ruangan. Untuk pengoperasiannya

menggunakan smartphone android sekaligus sebagai antara muka untuk memasukkan

jadwal perkelas hanya staf PSTI UNRAM yang akan mengoperasikan aplikasinya.

Dengan begitu AC bisa otomatis menyala sesuai jadwal mata kuliah dan bisa mati

secara otomatis setelah 30 menit tidak ada orang di dalam ruangan.
Dendrobine Suppresses Lipopolysaccharide‐induced Gut Inflammation in a Co‐culture of Intestinal Epithelial Caco‐2 Cells and RAW264.7 Macrophages
Authors: Liu Huifan , Liang Jiaxi , Xiao Gengsheng , Ma Lukai , Wang Qin
Published: April 2021

We evaluated dendrobine for its potential effect on Inflammatory Bowel Disease (IBD) progression using the intestinal epithelial Caco‐2/RAW264.7 macrophage co‐culture cell model. The results showed that dendrobine maintained the tight junction (TJ) proteins in co‐cultured Caco‐2 cells, suggesting its protective effect on intestinal integrity. Moreover, the findings indicated that the dendrobine group downregulated levels of tumor necrosis factor‐α(TNF‐α), proinflammatory Interleukin (IL)‐1βand IL‐6, and inflammatory markers such as cyclooxygenase‐2 (COX‐2) and inducible nitric oxide synthase (iNOS) in co‐cultured RAW264.7 cells. Additionally, dendrobine‐mediated anti‐inflammatory effects were observed based on the inhibition of LPS‐induced proinflammatory mediators of nuclear factor kappa B (NF‐κB)‐related signaling. These results demonstrated the protective effect of dendrobine at effectively ameliorating intestinal barrier disruption and inhibiting activation of the NF‐κB pathway in macrophages through the intestinal barrier.
Community Responses toward COVID-19 Pandemic: An Online Survey Study
Authors: Baeda Abd. Gani , Muhdar Muhdar , Tulak Grace Tedy , Naim Rosani , Rosmiati Rosmiati , Siagian Heriviyatno Julika
Published: April 2021

COVID-19 has become a frightening pandemic and has spread throughout theworld with an unprecedentedly high death rate. Community compliance withgovernment appeals must be accompanied by knowledge, attitudes, and practicesin dealing with this epidemic. This study aims to investigate the Knowledge,Attitude, and Practice of Kolaka residents against the COVID-19 outbreak. Thisresearch is descriptive-analytic with a Cross-Sectional approach. The sample usedin this study were 1,010 respondents aged 17 to 65 years, having gmail and y-mail accounts, mastering the internet became the criteria for respondentinclusion in this study. The questionnaire used was the adoption of previousstudies and modified according to conditions. Data were analyzed bivariate usingthe Chi-Square test with standard p-value<0.05. The results obtained showed thatthe Kolaka community had good knowledge (49.6%), a confident attitude ofcontrolling the plague (70.4%), and had a high level of vigilance (79.6%) towardsCOVID-19. There is a relationship between knowledge with practice p-value=0.000, while attitude has no relationship with practice with p-value=0.862.The massive dissemination of information through existing media has greatlyhelped the community increase their knowledge of COVID-19, which will furthersupport the formation of a confident attitude to control this disease and increasevigilance in their daily life practices during this pandemic.