bluuebunny/crossref_metadata_2025 huggingface dataset:
Twin Peaks 2.0: Avoiding Influence Over an Australian Financial Regulator Assessment Authority
Authors: Schmulow Andrew , Mazzola Paul , de Zilva Daniel
Published: September 2021

Globally, financial system regulators are susceptible to deliberate and inadvertent influence by the industry that they oversee and, hence, are also susceptible to acting to benefit the industry rather than the public interest – a phenomenon known as ‘regulatory capture’. Australia, arguably, has an optimal model of financial system regulation (a ‘Twin Peaks’ model) comprising separate regulators for prudential soundness on the one hand, and market conduct and consumer protection on the other. However, the current design of the Twin Peaks model has not been sufficient to prevent and address prolonged and systemic misconduct that culminated in a public Royal Commission of Inquiry into misconduct in the industry. Subsequent to the Royal Commission and other inquiries, the Department of Treasury has proposed legislation to establish an Assessment Authority to assess the effectiveness of the Twin Peaks regulators. The proposal includes enquiries by an Assessment Authority into the regulators’ independence, so as to identify instances of, and thereby mitigate, their capture. As with all financial system regulators, the Assessment Authority itself may be susceptible to regulatory capture, either by the Twin Peaks regulators, or by the financial industry. Thus, this paper poses the question: how can the new Assessment Authority be optimally constituted by legislation, and operated, to effectively oversee the effectiveness of the regulators, but itself remain insulated from the influence of the regulators and industry? We analyse the primary sources of influence over financial system regulators that the Assessment Authority will likely face and recommend ways in which a robust design of the Assessment Authority can mitigate those sources of influence. In doing so, we adopt an inter-disciplinary approach, drawing upon not only regulatory theory but also for the first time in relation to this question, organisational psychology. Our findings address gaps in the proposed legislation currently before Federal Parliament and propose methods by which those gaps may be filled, in order to ensure that this important reform to Australia’s financial regulatory regime has the greatest chance of success.
The Interplay between Divine, Victim, and Self-forgiveness: The Relationship between Three Types of Forgiveness and Psychological Outcomes
Authors: Kim Jichan , Ragasajo Lemuel J. C. , Kolacz Rebekah L. , Painter Kinsey J. , Pritchard John D. , Wrobleski Ashlyn
Published: September 2021

It is conceivable that one’s level of self-forgiveness is likely to be influenced by the extent to which one feels forgiven by God. Also, self-forgiveness, especially when the self-offense involves wronging another, is likely to be influenced by the extent to which one feels forgiven by the victim. Therefore, this study was aimed at simultaneously examining the interplay between divine, victim, and self-forgiveness as well as their effects on psychological outcomes. In Study 1, we examined the relative strength of divine and victim forgiveness as predictors of self-forgiveness and found that divine and victim forgiveness predicted self-forgiveness independently from each other. In Study 2, we examined the unique effects of three types of forgiveness on psychological outcomes and found that while all three types of forgiveness are associated with each other, after controlling for the other two types of forgiveness, self-forgiveness alone predicted anger, anxiety, and depression. A further analysis showed that self-forgiveness mediated the relationship between divine and victim forgiveness and psychological outcomes. In other words, divine and victim forgiveness contribute to self-forgiveness, which in turn lead to better psychological outcomes.
Race-Based Stress Reactions and Recovery: Pilot Testing a Racial Trauma Meditation
Authors: Hargons Candice , Malone Natalie J. , Montique Chesmore S. , Dogan Jardin , Stuck Jennifer , Meiller Carolyn , Sullivan Queen-Ayanna , Sanchez Anyoliny , Bohmer Carrie , Curvey Rena M. G. , Tyler Kenneth M. , Stevens-Watkins Danelle
Published: September 2021

Twenty-six Black collegians were exposed to a vicarious racial harassment stimulus (VRHS) then randomized into a Black Lives Matter Meditation for Healing Racial Trauma condition or a silence control condition. Heart rate (HR) was recorded throughout the experiment. Semi-structured interviews were then conducted to elicit participants’ appraisal of the VRHS and meditation. Using a Qual:Quan mixed methods experimental design, this pilot study qualitatively categorized how participants (1) described their reactions to the VRHS and (2) appraised the meditation. Participants described three types of race-based stress reactions and reported mostly positive appraisal of the meditation, although some indicated that it would not be a preferred coping strategy. To triangulate the quantitative findings, we found a significant increase in HR during VRHS. The meditation group displayed statistically significant reductions in HR from stimulus to the end of meditation; however, there were no statistically significant differences between the control and meditation groups. Results have implications for understanding and facilitating race-based stress recovery.
Using platelet-rich fibrin scaffolds with diced cartilage graft in the treatment of empty nose syndrome
Authors: Chang Chin-Fang
Published: September 2021

Empty nose syndrome (ENS) is a rare entity in patients who undergo sinonasal surgery due to over-resection of the turbinate. This syndrome leads to debilitating symptoms that include dry nose, painful nasal breathing, paradoxical nasal obstruction, crusting, and sleep disorder. The goal of surgical treatment is to reestablish the volume of the turbinates to rehabilitate the nasal resistance. Endonasal microplasty with cartilage implants on the lateral wall of the nasal cavity is useful for creating the neoturbinate. Here, we present 2 cases that describe the management of empty nose syndrome by endonasal microplasty using platelet-rich fibrin (PRF) scaffolds embedded with a diced cartilage graft. The integration of the PRF scaffolds with diced cartilage efficiently facilitated the reestablishment of the neoturbinate. This autologous biomaterial is suitable for the treatment of ENS.
3D Real IR MR Findings in Acoustic Neuromas: Altered Perilymph Metabolism
Authors: Shi Suming , Guo Ping , Li Wenquan , Wang Wuqing
Published: September 2021

Objectives

This study aimed to investigate the perilymph metabolism by analyzing the 3D real IR MR findings in acoustic neuroma (AN) after intravenous administration of gadolinium (Gd).

Methods

Eleven patients (6 men and 5 women) diagnosed with AN were included, and 3D real IR MRI was performed 4 hours after intravenous Gd injection. The signal intensity and details of inner ear, tumor, and internal auditory canal (IAC) by MRI were analyzed.

Results

Four patients had tumors confined to the IAC, and 5 had tumors that extended to the cerebellopontine angle cistern. The signal intensity of the cochlea, vestibule, and IAC fundus was conspicuously enhanced in 3D real IR images than the control side. One patient had a tumor in the cochlea, in which the signal intensity of the semicircular canal and vestibule was increased. One patient had an intravestibular tumor in which the signal intensity of the semicircular canal was increased and the cochlea had endolymphatic hydrops in the affected ear.

Conclusions

The synchronously increased signal intensity in the inner ear and IAC may indicate that IAC may serve as a channel for removal of the perilymph in the inner ear; the blockage by the tumor may have changed the hydrodynamics of the perilymph to cause a longer retention of Gd in the inner ear.
Do Revenues Matter More Than Earnings for Initial Public Offerings?
Authors: Massel Norman , Park Jung Eun “JP” , Reichelt Kenneth J.
Published: September 2021

We demonstrate that investors in initial public offering (IPO) firms value revenues and that the number of U.S. Securities and Exchange Commission (SEC) revenue recognition comment letters issued on the S-1 registration statement are positively associated with reported revenues. We also find that IPO managers report revenues opportunistically in the fiscal year just prior to the offer. In additional analysis, we find that discretionary revenues are associated with significantly higher first day IPO stock returns but significantly lower 1 year stock returns. Our results are consistent with the incentives of managers to report revenues opportunistically outweighing the higher monitoring and regulatory scrutiny pre-IPO.
Blessing or Burden: Transitions Into Eldercare and Caregiver Mental Health
Authors: Reynolds Jeremy , James Katie
Published: September 2021

Caring for one’s parents can be good or bad for mental health. Guided by theories suggesting that caregiving work brings both demands and benefits, we examine if mental health outcomes depend on variations in caregiving arrangements. Using waves 5–17 from the Household Income and Labor Dynamics in Australia Survey (16,802 respondents; 115,176 person-years), we divide men and women caregivers into four groups based on their responsibility (main vs. secondary caregiver) and the location of the care recipient (inside or outside the caregiver’s household). We also examine how caregivers’ experiences are moderated by the social support they have. On average, caregivers experience no change in mental health. However, women with low social support who become main caregivers for resident parents experience declines in mental health. Men with low social support who become main caregivers for non-resident parents experience improved mental health. These results suggest that caregiver outcomes reflect different caregiving arrangements.
Toward a Better Understanding of the Associations Among Different Measures of Father Involvement and Parenting Alliance
Authors: Matte-Gagné Célia , Turgeon Nicolas R.- , Bernier Annie , Cyr Chantal
Published: September 2021

The variety of measurement methods used in fathering research to assess fathers’ involvement makes it difficult to summarize what we know about paternal involvement and its correlates and antecedents. Aiming to shed light on the potential consequences of using different measures of paternal involvement, this study examined: (a) the associations among three measures of father participation in parental activities, namely self- and mother-reported questionnaires and a father-completed time diary, and (b) their respective associations with a well-documented predictor of father involvement, i.e., parenting alliance. The sample included 80 parental couples with a 6-month-old child. Although moderate associations were found among measures of father involvement, only the maternal and paternal questionnaires were associated with parenting alliance. These results suggest that time diaries and questionnaires tap into different aspects of father involvement that can have distinct correlates and determinants. Better acknowledgment of the diverging results attributable to the use of different measurement approaches of father involvement is needed.
“Be free together rather than confined together”: A qualitative exploration of how relationships changed in the early COVID-19 pandemic
Authors: Vowels Laura M. , Francois-Walcott Rachel R. R. , Perks Rhia E. , Carnelley Katherine B.
Published: September 2021

Due to the COVID-19 pandemic, many couples are staying at home together for an extended period. This is likely to impact couples as they navigate their responsibilities while maintaining a healthy relationship during uncertain times. We conducted qualitative research to investigate participants’ perception on how relationships changed considering COVID-19 and social distancing measures. Data were collected through open-ended surveys ( n = 200) which were completed weekly for 5 weeks and by semi-structured interviews ( n = 48). Overall, 28.6% of relationships had gotten better, 28.6% worse, 29.9% stayed the same, and 8.0% were mixed. Both methods highlighted similar themes (communication, space, togetherness, sharing responsibilities, quality time, and support networks) including 15 sub-themes in the interviews. The study provides a unique insight into the impact of COVID-19 on relationships and provides techniques that have been identified by couples to increase relationship satisfaction for their own and others’ relationships.
Potential benefit of GnRH-agonist treatment before uterine artery embolization for large fibroids: MRI prediction of fibroid volume reduction
Authors: Lee Woo Jin , Kim Man-Deuk , Han Kyunghwa , Won Ye Ryung , Alqahtani Abdulrahman , Moon Sungmo , An Hyeongsu
Published: September 2021

Background

Signal intensity (SI) of predominant fibroid (F1) on T2-weighted (T2W) images is useful for predicting the volume reduction response after gonadotropin-releasing hormone (GnRH)-agonist treatment. Few studies have been published regarding when and how to use GnRH agonist before UAE.

Purpose

To investigate magnetic resonance imaging (MRI) prediction of volume reduction rate (VRR) of large fibroids after GnRH-agonist treatment before uterine artery embolization (UAE) as well as the efficacy of UAE based on MRI.

Material and Methods

Data from 30 patients with a large fibroid and MRI results both before and after GnRH-agonist treatment were retrospectively analyzed. Indications for GnRH-agonist treatment are fibroids with a maximum diameter ≥10 cm or pedunculated submucosal fibroids ≥8 cm. GnRH agonist (3.75 mg leuprolide acetate) was administered subcutaneously once per month 2–6 times. SI of F1 on T2W imaging was measured: the SI was referenced to the SI of the rectus abdominis muscle (F/R).

Results

Mean maximum fibroid diameter was 11.1 ± 1.9 cm (range = 8.0–15.5 cm). Mean number of GnRH-agonist injections before UAE was 2.8 (range = 2–6). For predicting VRR ≥50% and <30%, the optimal cut-off values of F/R were 2.58 (sensitivity 80%, specificity 80%) and 1.69 (sensitivity 100%, specificity 70%), respectively. Of the 30 patients, fibroid infarction was complete in 29 (96.7%).

Conclusion

SI of F1 on T2W imaging is useful for predicting the volume reduction response after GnRH-agonist treatment. After GnRH-agonist treatment for large fibroids, UAE is effective to achieve complete infarction of fibroids.
Nickel nanoparticles induce hepatotoxicity via oxidative and nitrative stress-mediated apoptosis and inflammation
Authors: Iqbal Shabnoor , Jabeen Farhat , Peng Cheng , Shah Muhammad Ajmal , Ijaz Muhammad Umar , Rasul Azhar , Ali Shujat , Rauf Abdur , Batiha Gaber ES , Kłodzińska Ewa
Published: September 2021

Nickel nanoparticles (Ni NPs) are utilized extensively in various industrial applications. However, there are increasing concerns about potential exposure to Ni NPs and consequent health effects. The aim of this study was to assess Ni NPs-induced liver toxicity in Sprague Dawley rats. Twenty-five rats were exposed to Ni NPs via intraperitoneal injection at doses of 15, 30, and 45 mg/kg per body weight for 28 days. Results from ICP-MS analysis showed an increase in the concentration of Ni NPs in a dose-dependent manner. The liver dysfunction was indicated by considerable production of ALT, AST, ALP, LDH, and TB in Ni NPs-treated rats. Histological examination demonstrated liver injuries (inflammatory cells, congestion, necrosis, and pyknosis) in exposed rats with dose-dependent severity of pathologies by semi-quantitative histograding system. To explore the toxicological pathways, we examined oxidative stress biomarkers and detected Ni NPs significantly elevated the levels of MDA and LPO while decreasing the levels of CAT and GSH. All the changes in biomarkers were recorded in a dose-dependent relationship. In addition, we found upregulated NF-kβ indicating activation of inflammatory cytokines. ELISA results of serum revealed a remarkable increase of nitrative stress markers (iNOS and NO), ATPase activity, inflammatory cytokine (IL-6, IL-1β, and TNF-α), and apoptotic mediators (caspase-3 and caspase-9) in Ni NPs-treated groups than the control. In summary, the result of this study provided evidence of hepatotoxicity of Ni NPs and insightful information about the involved toxic pathways, which will help in health risk assessment and management, related preventive measures for the use of Ni-NPs materials.
Work Values and Job Satisfaction: The Mediating Role of Basic Psychological Needs at Work
Authors: Busque-Carrier Mathieu , Ratelle Catherine F. , Le Corff Yann
Published: September 2021

This study investigated the mediating role of basic psychological needs at work in the association from work values to job satisfaction. Using a four-factor model of work values, we tested how each work value factor was related to basic psychological need satisfaction and frustration at work. The sample included 228 workers (72% female) surveyed twice over a 7-week interval. Results showed that need satisfaction at work was positively predicted by intrinsic and social work values and negatively predicted by extrinsic work values. Need frustration at work was positively predicted by extrinsic and status work values and negatively predicted by intrinsic work values. Also, need satisfaction fully mediated the relationship from intrinsic, extrinsic, and social work values to job satisfaction. These findings suggest that organizational and career development interventions aiming to enhance employees need satisfaction at work should aim to promote growth-oriented work values endorsement rather than instrumental work values.
Acrylamide impairs the developmental potential of germinal vesicle oocytes by inducing mitochondrial dysfunction and autophagy/apoptosis in mice
Authors: Gao Ji-Guang , Yang Jian-Ke , Zhu Lei , Xu Cheng , Nie Liu-Wang
Published: September 2021

Background: Acrylamide (ACR), an important endogenous contaminant in carbohydrate-rich foods, has been involved in various negative effects on multiple organ networks, including the reproductive system. Previous studies have reported that ACR affects oocyte quality and fertility. Purpose: This study aimed to explore the toxic effects and regulatory mechanisms of ACR on mouse germinal vesicle (GV) oocytes. Research Design: In this study, adult female mice were exposed to ACR at 10 mg/kg/day/body weight through their drinking water continuously for 4 weeks. Study Sample and Data Analysis: The mitochondrial function, autophagy/apoptosis, and development potential of GV oocytes were investigated. Results: The results showed that ACR reduced the oocyte diameter, sperm-binding ability, parthenogenetic activation and in vitro fertilization (IVF) rate, and development potential of pre-implantation embryos. We also found that ACR exposure disrupted chromatin configuration, mitochondrial distribution, and membrane potential (Δφm) of oocytes. Actin filament expression was significantly reduced in both the membrane and cytoplasm of mouse oocytes. Moreover, ACR exposure increased LC3-positive signals, early apoptosis rate, aberrant ATG3, ATG5, LC3, Beclin1, and mTOR mRNA expression. Conclusions: These results suggest that ACR exposure can affect the developmental potential of GV oocytes by inducing mitochondrial dysfunction, actin filament assembly, and autophagy/apoptosis.
How Does Bank Diversification Affect Efficiency? Insights of the Central Europe
Authors: Moudud-Ul-Huq Syed , Mateev Miroslav , Abbas Faisal , Hossain Mahmud , Sohail Hafiz M.
Published: September 2021

This study empirically aims to investigate the influence of diversification on cost efficiency in the context of 10 Central European countries’ (such as Hungary, Poland, Germany, Slovakia, Slovenia, Romania, Croatia, Serbia, Czech Republic and Switzerland) banks from 2011 to 2017 and employs two-stage least squares (2SLS) estimator as a methodological approach. It uses cost efficiency (EFF) and diversification (asset and income) as the main explanatory variables. Our baseline results show that asset and income diversification have a negative and significant effect on bank efficiency. Leverage (LEV) and the growth of gross domestic product (GDP) do not influence bank efficiency. From the bank control and macro-economic level variables, it is found that one-year lagged cost efficiency (EFFLAG), assets diversification (AD), income diversification (ID), assets growth (AG), return on assets (ROA), return on equity (ROE), net interest margin (NIM) and rate of inflation (INFR) have a significantly negative relationship with the bank efficiency in the Central European countries. More importantly, both ID and AD tend decreasing the efficiency in the region.
Improving Relationships and Student Outcomes Through Restorative Practices
Authors: Forsberg Malinda L. , Leko Melinda M.
Published: September 2021

Students who exhibit externalizing behaviors may impede learning in the classroom and lead to cycles of negative teacher–student interactions. Positive relationships among students, peers, and educators serve as a protective factor against childhood adversity and are a predictor of academic, social, and behavioral outcomes. By incorporating restorative practices into their daily routine, educators and school leaders can strengthen relationships and promote safety while ensuring students are learning prosocial skills needed for future success.
Signaling Democratic Progress through Electoral System Reform in Post-Communist States
Authors: O’Brochta William , Cunha Silva Patrick
Published: September 2021

The international community invests heavily in democracy promotion, but these efforts sometimes embolden leaders not interested in true democratic reform. We develop and test a formal model explaining why this occurs in the context of electoral system reform—one of the most important signals of democratic quality. Our formal model characterizes leaders as either truly reform minded or pseudo-reformers, those who increase electoral system proportionality in order to receive international community benefits while engaging in electoral fraud. We hypothesize that the international community will be more (less) likely to detect fraud when leaders decrease (increase) proportionality, regardless of whether there is evidence of numerical fraud. Using a mixed-methods approach with cross-national and case study data from post-Communist states, we find that the international community is generally less likely to detect fraud following an increase in proportionality and vice versa. We suggest that democracy promoters over-reward perceived democratic progress such that pseudo-reformers often benefit.
Modeling the Adverse Childhood Experiences Questionnaire–International Version
Authors: Gette Jordan A. , Gissandaner Tre D. , Littlefield Andrew K. , Simmons Chelsy S. , Schmidt Adam T.
Published: September 2021

Adverse childhood experiences (ACEs) are related to a host of deleterious physical and mental health outcomes. The ACE–International Questionnaire (ACE-IQ) was developed to assess categories of ACEs (e.g., sexual, emotional, and physical abuse) in internationally representative samples. Though the ACE-IQ has been used world-wide, little work has examined the structure of this measure. Further, much of the modeling techniques implemented lacked theoretical rationale. The present work used two principal components analyses (PCA) to evaluate the ACE-IQ structure using both the identified ACE categories as defined by the World Health Organization (WHO) and using the ACE-IQ items as individual indicators. Using the WHO method, a two-component structure was indicated. Alternatively, a PCA of the individual items yielded a six-component structure. Results highlight the importance of theoretically grounded measure evaluation and the potential distinctions amongst types of ACEs. Implications and future directions for research and practice are discussed.
Single dose of atezolizumab plus chemotherapy in active psoriasis with advanced non-small cell lung cancer
Authors: Wong Pui Yee , How Soon Hin , Ismail Irnani , Hassan Radhiana
Published: September 2021

Introduction

Immunotherapy has been recognized as the standard of care in addition to chemotherapy in the treatment of advanced non-small cell lung cancer. Most immunotherapy trials, however, exclude patients with autoimmune disease owing to concerns of disease exacerbation.

Case report

We report a case of a patient with advanced non-small cell lung cancer and underlying active psoriasis who experienced a remarkable response, without developing psoriasis flares, following treatment with a single dose of atezolizumab and first-line chemotherapy.

Management and outcome

The patient remained asymptomatic 10 months since treatment discontinuation, without disease progression, despite having received only a single dose of atezolizumab and six cycles of chemotherapy.

Discussion

Little is known about the optimum duration required to achieve a durable response with immunotherapy. Patients with autoimmune disease are commonly excluded from immunotherapy trials owing to a higher risk of autoimmune disease flares or immune-related adverse events. The remarkable outcome observed in this case offers some insights into the possible durable response with limited doses of immunotherapy and a safer approach for administering immunotherapy in patients with autoimmune disease. Initiating chemotherapy to induce remission in active autoimmune disease prior to administering immunotherapy could potentially be an ideal approach that facilitates the use of immunotherapy in this patient population.
Consumer Job Journeys
Authors: Bettencourt Lance A. , Harmeling Colleen , Bhagwat-Rana Yashoda , Houston Mark B.
Published: September 2021

This article introduces the consumer job journey as a more holistic perspective by which to understand consumption journeys undertaken to acquire and use goods and services. It aids scholars and managers by helping make evident some key consumer decisions and behaviors that otherwise would be invisible. Four tenets lay the foundation for the concept of a consumer job journey, establishing some key differences relative to a traditional perspective on consumption journeys. A consumer job journey involves a sequence of goal-directed steps (and associated evaluative criteria) in pursuit of an overall job and the consumer actions directed by these steps to acquire, assemble, and integrate market and nonmarket resources. Propositions highlight the consumer’s role as an active project manager who continually adapts their resource configuration given job journey goal priorities, psychological tensions, and disruptions. In combination, the tenets and propositions highlight both research gaps and unique managerial implications.
Tensile behavior of stud connectors in high strength concrete
Authors: Li Fuhai , Gao Hao , Jiang Yilin , Wen Tao , Zhan Yulin , Chen Zhao , Shen Dong
Published: September 2021

Stud connectors are commonly used in steel-concrete composite structures. As high strength concrete (HSC) will be applied in the construction of a composite structure, it is needed to study the performance of stud connectors in HSC. In this study, tension (pull-out) tests were conducted on the studs with different combinations of diameters- d(13, 16, and 19 mm) and effective embedment depths- h ef (40, 60, and 80 mm) in HSC with a 28-day compressive strength of 88 MPa. Based on the experimental results, the concrete breakout failure mode dominates and only the scenario with the smallest diameter and largest h ef is controlled by steel failure mode. Because of high strength, the steel failure occurs at smaller h ef/ d in HSC than normal concrete. In the concrete breakout failure mode, brittle load–displacement behaviors are presented and the angle of the breakout cone ranges from 30∼35°, which is close to the concrete capacity design (CCD) method. Also, the ultimate tensile strength ( N u), stiffness, and pre-peak ductility are dependent on h ef and diameter . The existing prediction models (CCD method and variable angle cone method) both overestimate the N u in HSC, which is due to its lower ratio tensile/compressive strength than normal concrete. Considering the mechanism of how the breakout cone is formed, a modified reduced_CCD method is proposed for predicting N u of studs in HSC.
Improving data quality and information utilization at Metema Primary Hospital, Amhara national regional state, Northwest Ethiopia 2018: Capstone project
Authors: Gonete Tajebew Z , Yazachew Lake , Endehabtu Berhanu F
Published: September 2021

Quality data for evidence-based decision making become a growing concern globally. Available information needs to be disseminated on time and used for decision making. Therefore, an effective Health Management Information System is essential to make evidence-based decision. This study aimed to measure the change in data quality and information utilization before and after intervention. Facility-based pre-post interventional study design was conducted at Metema hospital from September/2016 to December30/2018. A total of 384 individual medical-records, HMIS registration-books and reports were reviewed. Training, supportive supervision and feedback were intervention packages. About 309 (80.5%) of charts were from outpatient department. Data recording completeness increased from 69.0% to 96.0%, data consistency increased from 84.0% to 99.5% and report timeliness enhanced from 66.0% to 100%. There was a statistically significant difference for data recording completeness between pre and post-intervention results with mean difference of −0.246 (−0.412, −0.081). Also, after the intervention, gap-filling feedback and supportive supervision were given to all departments. In addition, four quality improvement projects were developed at post-intervention phase. The level of data quality and use was improved after the intervention. So, designing and implementing intervention strategies based on the root causes will help to improve data quality and use.
Good listening: A key element in establishing quality in qualitative research
Authors: Lavee Einat , Itzchakov Guy
Published: September 2021

What is “good” qualitative research? Considerable literature articulates criteria for quality in qualitative research. Common to all these criteria is the understanding that the data gathering process, often interviews, is central in assessing research quality. Studies have highlighted the preparation of the interview guide, appropriate ways to ask questions, and especially the interaction between interviewer and interviewee. To a lesser extent, qualitative scholars mention the importance of the interviewer’s listening abilities in obtaining the interviewee’s cooperation. Based on results of listening studies in the fields of psychology and organizational behavior, we argue that good listening is crucial for assessing the quality of qualitative research, yet remains a blind spot in qualitative data gathering. Drawing on our experience as qualitative researcher and listening researcher, we present practices for enhancing good listening in qualitative research, thereby enabling researchers to calibrate themselves as research instruments and obtain richer data.
A qualitative fallacy: Life trapped in interpretations and stories
Authors: Bøe Tore Dag , Bertelsen Bård , Larsen Inger Beate , Topor Alain
Published: September 2021

This paper points out some problematic aspects of qualitative research based on interviews and uses examples from mental health. The narrative approach is explored while inquiring if the reality of life here is forced into the formula of a chronological story. The hermeneutic approach, in general, is also examined, and we ask if the reality of life in this scenario becomes caught up in a web of interpretations. Inspired by ideas from Bakhtin and phenomenology, we argue for interview-based research that stays with unresolvedness and constantly question the web of interpretations and narratives that determine our experiences. This also chimes with certain dialogical practices in mental health in which tolerance of uncertainty is the guiding principle. Concludingly, we suggest that interview-based research could be a practice of ‘un-resolving’ in which researchers, together with the participants, look for cracks, contradictions, and complexities to prevent the qualitative fallacies of well-organized meanings and well-composed stories.
Participatory research in and against time
Authors: Rosen Rachel
Published: September 2021

The staccato rhythms of experiential time remain obscured in much of the literature on participatory research, where time is treated as a reassuring constant – a backdrop for human activity. This article addresses the discordances between lived temporalities and existing theorisations of participatory methodologies. It takes participatory research with lone child migrants as a particularly rich case to think with, given the proliferation of contradictory and often punitive applications of time these young people encounter in their interactions with migration and welfare regimes. The core argument developed is that unless temporality is given due theoretical and methodological attention, aims of contesting and unsettling inequities through participatory research will have limited success and can wind up reproducing exclusions and oppressions. In response to these critiques, the paper temporalizes participatory research through three reconstructions: working with and against time, de-centring shared time and collectivising the time of participatory research.
Comparison of the sensitivity of patient-reported outcomes for detecting the benefit of biologics in severe asthma
Authors: Hyland Michael E , Lanario Joseph W , Menzies-Gow Andrew , Mansur Adel H , Dodd James W , Fowler Stephen J , Hayes Gemma , Jones Rupert C , Masoli Matthew
Published: September 2021

Background

The sensitivity of patient-reported outcomes (PROs) to detect the effects of treatment change depends on the match between the change in items of the PRO and the change that takes place in a sample of people. The aim of this study is to compare the sensitivity of different PROs in detecting changes following the initiation of biologic treatment in asthma. Methods: Patients starting a biologic treatment as part of clinical care completed the Asthma Control Questionnaire (ACQ-6), the Severe Asthma Questionnaire (SAQ and SAQ-global scores) and the EQ5D (EQ-5D-5L and EQ5D-VAS) at baseline. They completed the ACQ-6, SAQ, SAQ-global and a retrospective global rating of change (GRoC) scale at weeks 4, 8 and 16 and completed the EQ-5D-5L and EQ5D-VAS at week 16. The SAQ-global and EQ5D-VAS differ but both are single item 100-point questions. Sensitivity was measured by Cohen’s D effect size at each of the three time points. Results: 110 patients were recruited. Depending on the time of assessment, effect size varied between 0.45 and 0.64 for the SAQ, between 0.50 and 0.77 for the SAQ-global; between 0.45 and 0.69 for ACQ-6; between 0.91 and 1.22 for GRoC; 0.32 for EQ-5D-5L and 0.49 for EQ5D-VAS. Conclusion: The sensitivity to change of a questionnaire varies with the time of measurement. The three asthma-specific prospective measures (SAQ, SAQ-global and ACQ-6) have similar sensitivity to change. The single-item EQ5D-VAS was less sensitive than the asthma specific measures and less sensitive than the single-item SAQ-global. The EQ-5D-5L was least sensitive.
Thermal protective performance of single-layer rib-knitted structure and its derivatives under radiant heat flux
Authors: Maurya Sandeep K , Uttamrao Somkuwar Viraj , Garg Hema , Das Apurba , Kumar Bipin
Published: September 2021

The compact construction of fire-resistant woven clothing designed for radiant heat flux protection limits the air permeability from the skin to the environment that risks thermal stress to the wearer. Knitted fabric is well known for its comfort and transmission properties. The inevitable porosity of the knitted fabric has restrained its application in fire-protective clothing. This study attempts to apply tuck and miss elements of a knitted structure to produce a compact yet comfortable flame-retardant fabric with maximum air permeability. The effect of radiant heat exposure at the intensity of 40 kW/m2 and 61 kW/m2 is analyzed for the designed sample. The tuck and miss stitches are used to modify rib-knitted structure and the second-degree burn time estimated using Stoll’s curve. The findings of this research show that a simple modification of rib structure with incorporation of miss stitch can enhance the second-degree burn time to 30 s at the radiant heat exposure of 40 kW/m2.
Cognitive and Central Vestibular Functions Correlate in People With Multiple Sclerosis
Authors: Cochrane Graham D. , Christy Jennifer B. , Sandroff Brian M. , Motl Robert W.
Published: September 2021

Background. Cognitive impairment is common, but poorly managed in people with multiple sclerosis (MS). Balance has been correlated with cognition in people with MS, potentially through shared utilization of central sensory integration pathways. Objective. This study characterized the relationship between central vestibular integration and cognition in people with MS through measurement of several clinical vestibular functions requiring central sensory integration and multiple cognitive domains. Methods. Forty people with MS and 20 controls completed a battery of vestibular and cognitive examinations targeting different central vestibular integration measures and different domains of cognition, respectively. Performance on these measures was compared between people with MS and controls, and then correlational analyses were undertaken between the vestibular and cognitive measures in the MS sample. Results. People with MS performed worse than controls on all vestibular and cognitive measures. There were consistent correlations between vestibular and cognitive measures in the MS sample. Factor analysis of vestibular functions yielded a single factor hypothesized to represent central vestibular integration that demonstrated a significant relationship with a composite cognitive measure in people with MS. Discussion. Our results suggest that vestibular and cognitive dysfunction may both arise from central sensory processing pathways in people with MS. This connection could be targeted through vestibular rehabilitation techniques that improve central sensory processing and both balance and cognition in people with MS.
A Taste of Virtual Culinary Medicine and Lifestyle Medicine—An Online Course for Medical Students
Authors: Poulton Ginger , Antono Amanda
Published: September 2021

As medical schools work to train the next generation of providers, including robust content in nutrition education is paramount. The National Academy of Sciences sets the benchmark for 25 hours of nutrition education in medical schools, though many schools do not meet this requirement. Usually, nutrition lectures in medical schools are given in the pre-clinical years and focus on biochemistry and micronutrients. During the COVID-19 pandemic, there was a unique opportunity to quickly develop and implement an elective course for 3rd and 4th year medical students at the University of North Carolina School of Medicine. A course was created in lifestyle medicine and culinary medicine, and all were delivered remotely through Zoom. This course would be simple to replicate at other institutions and was very well received. This article will describe more of the resources, methods, and reactions to this course.
Practical Considerations in Qualitative Health Research During the COVID-19 Pandemic
Authors: Varma Deepthi S. , Young Mary E. , Kreider Consuelo M. , Williams Katherine , Vaddiparti Krishna , Parisi Christina , Semeah Luz M.
Published: September 2021

The COVID-19 pandemic has forced both quantitative and qualitative health researchers to adapt and strategize data collection strategies without causing any harm to the participants or researchers. This has resulted in utilizing various types of strategies such as online surveys and synchronous virtual platforms such as Zoom and Webex. This transition from face-to-face to synchronous online platforms has helped in increasing coverage as well as reaching participants who are otherwise unreachable. While quantitative health researchers seem to have made a seamless transition to synchronous online platforms, qualitative health researchers who rely on studying participants in their “real-world-settings” are facing unique challenges with online data collection strategies. This article critically examines the benefits and challenges of implementing qualitative health research studies via synchronous online platforms and provides several practical considerations that can inform qualitative health researchers. It can also assist Institutional Review Board members in reviewing and implementing qualitative health research study protocols in a manner that preserves the integrity, richness, and iterative nature of qualitative research methodology.
Azerbaijani youth in transition: Is the state youth policy effective enough?
Authors: Valiyev Anar , Babayev Abbas
Published: September 2021

This article analyzes the role of the state youth policy of Azerbaijan in supporting young people through their transition from school to work, which is one of the stages when young people can be in particularly fragile situation if not provided with necessary opportunities. The reason for studying the case of Azerbaijan is a considerable share of youth Not in Employment, Education, or Training (NEET youth) among the country’s youth community. The NEET indicator is considered as a comprehensive indicator within the post-2015 Sustainable Development Agenda to measure youth exclusion and marginalization. The findings of this research demonstrate that while the government assumes a broad responsibility to provide youth with education and employment opportunities to support their transition, these intentions have not been translated into real actions. An alarming situation of the country’s youth population is at risk of further exacerbation due to poor understanding of local realities by such global advocates for youth development as United Nations. We discuss this considering the flaws in the operationalization and localization of the concept of the “youth participation” promoted by the United Nations to advance youth interests.
Intervariability in radiographic parameters and general evaluation of a low-dose fluoroscopic technique in patients with idiopathic scoliosis
Authors: Wong Christian , Adriansen Jens , Jeppsen Jytte , Balslev-Clausen Andreas
Published: September 2021

Background

Radiographic images in adolescent idiopathic scoliosis (AIS) have a potential radiation-induced oncogenic effect; thus lowering radiation dose by using fluoroscopic imaging technique of low-dose fluoroscopic technique (LFT) which might be relevant for clinical evaluation.

Purpose

To compare radiographs of LFT with gold standard radiographs for AIS ordinary radiographic technique (ORT).

Material and Methods

Image quality was evaluated for LTF and ORT of a child phantom and two 3D-printed models (3DPSs) of AIS. We measured the primary physical characteristics of noise, contrast, spatial resolution, signal-to-noise ratio, and contrast-to-noise ratio. Three independent evaluators assessed the radiographs by observer-based methods of image criteria (ICS) and visual grading analysis(VGAS). Radiation doses were evaluated by the dose-area-product (DAP) of the 25 phantom radiographs. Reliability and agreement of Cobb’s angle (CA) and other radiographic parameters were evaluated on the 3DPSs and reliability on 342 LFT.

Results

The average noise and contrast were approximately 15-fold higher for LFT. SNR and CNR were similar. Overall, ICS and VGAS were 3-fold higher for ORT than for LFT for L3 and similar for Th6. Reliability and agreement were good for the experimental LFT, and the interclass correlation coefficient for CA was 0.852 for the clinical LFT. The average DAP and effective dose for LFT were 8-fold lower than those for ORT.

Conclusion

In conclusion, LFT is reliable for CA measurements and is thus useful for clinical outpatient follow-up evaluation. Even though the image quality is lower for LFT than ORT, the merits are the substantially reduced radiation and a lowered malignancy risk without compromising the measurement of Cobb’s angle, thus following the principles of ALARA.
Drug-sensitivity test and analysis of drug-resistant mutations in Mycobacterium tuberculosis isolates from Kashgar, China
Authors: Ma Zhongchen , Sun Tianhao , Bai Xinyu , Ji Xiang , Zhang Qian , Wu Jiangdong , Wang Zhen , Chen Chuangfu
Published: September 2021

Introduction

In recent years, drug-resistant Mycobacterium tuberculosis strains have gradually become widespread. Most drug resistance is related to specific mutations. We investigated M. tuberculosis drug resistance in the Kashgar area, China.

Methods

The drug-susceptibility test was conducted to clinical isolates of M. tuberculosis. Genomic-sequencing technology was used for the drug-resistant strains and the significance of DNA sequencing as a rapid aid for drug-resistance detection and the diagnosis method was evaluated.

Results

The resistance rates of clinical isolates to rifampicin (RFP), isoniazid (INH), streptomycin (SM), ethambutol (EMB), and ofloxacin (OFX) were, respectively, 4.4%, 12.3%, 8.8%, 2.6%, and 3.5%. The single- and multi-drug resistance rates were, respectively, 80.0% and 20.0%. The resistance genes RopB, katG, InhA, RpsL, rrs, gyrA, and embB displayed codon mutations, while InhA was mutated in its promoter region. Kappa scores, evaluating the consistency between DNA sequencing and the resistance ratio methods for the detection of isolates’ resistance to RFP, INH, SM, OFX, and EMB, were 1, 0.955, 0.721, 0.796, and 1, respectively.

Conclusion

The resistance rate of INH and SM is relatively high in the Kashgar area. Detection of mutations in RopB, katG, InhA, RpsL, rrs, gyrA, and embB by DNA sequencing can predict drug resistance of M. tuberculosis strains with high sensitivity and specificity, and can be used for diagnosis.
Apelin: A new biomarker in fatty liver disease
Authors: Kalyon Semih , Altun Özgür , Pala Ayşe Selcen , Tükek Tufan
Published: September 2021

Apelin is a peptide known for its insulin-sensitizing effect. This study aimed to examine the relationship between apelin and fatty liver disease. Non-diabetic patients were evaluated by ultrasound in this prospective, single-center, case-control study between 1 April 2020 and 1 April 2021. Serum apelin levels were measured, and the relationship with ultrasonography results and degree of hepatosteatosis was examined. Statistical analysis was carried out using NCSS 2007. This study was conducted with 80 non-diabetic participants, 53 females and 27 males. The mean age of the cases was 40.55 ± 13.82 (interquartile range = 27–51) years, and their mean body mass index (BMI) was 29.34 ± 7.44 (interquartile range = 23.4–35.2) kg/m2. There was no hepatosteatosis according to ultrasound in 42% (n = 34) of the cases. When patients with or without hepatosteatosis were compared, there was no difference in terms of gender, alanine aminotransferase (ALT), and hemoglobin levels, whereas fasting blood glucose (FBG), HOMA-IR, triglycerides, LDL-cholesterol, BMI, creatinine, and age were higher in the group with hepatosteatosis. Apelin was found to be lower in patients with non-diabetic hepatosteatosis than in those without hepatosteatosis ( p = .001). As the degree of fatty liver increased, the apelin level decreased further. There was also a negative correlation between apelin and age. However, the relationship between apelin and hepatosteatosis was independent of age. In non-diabetic patients with fatty liver disease, compared to those without fatty liver disease, serum apelin level was lower and was negatively correlated with the degree of steatosis, independent of age.