bluuebunny/crossref_metadata_2025 huggingface dataset:
P50 implies adverse clinical outcomes in pediatric acute respiratory distress syndrome by reflecting extrapulmonary organ dysfunction
Authors: Kim Yura , Jung Jae Hwa , Kim Ga Eun , Park Mireu , Lee Myeongjee , Kim Soo Yeon , Kim Min Jung , Kim Yoon Hee , Kim Kyung Won , Sohn Myung Hyun
Published: August 2022

Hypoxemia and multiple organ dysfunction are significant contributors to mortality in patients with pediatric acute respiratory distress syndrome (PARDS). P50, the oxygen tension at which hemoglobin is 50% saturated, is a measure of hemoglobin-oxygen affinity, and its alteration might have implications for tissue hypoxia and organ dysfunction. The purpose of this single-center, retrospective study was to evaluate P50 levels in PARDS and to determine the association between P50 and clinical outcomes. The study included 212 children diagnosed with PARDS according to the Pediatric Acute Lung Injury Consensus Conference definition who required invasive mechanical ventilation and had arterial blood gas results of hemoglobin oxygen saturation < 97% at the time of diagnosis. P50 levels were calculated using Doyle’s method, and organ dysfunction was assessed using the Pediatric Logistic Organ Dysfunction-2 score. Most patients exhibited more than one dysfunctional extrapulmonary organ at PARDS onset. P50 increased with increasing PARDS severity (mild (26.6 [24.9–29.6]), moderate (26.8 [25.0–29.5]), and severe PARDS (29.1 [26.1–32.4] mmHg; P = 0.025). Moreover, P50 demonstrated a significant positive association with extrapulmonary organ dysfunction score (β = 0.158, P = 0.007) and risk of mortality (adjusted hazard ratio, 1.056; 95% confidence interval, 1.015–1.098; P = 0.007), irrespective of initial PARDS severity. The relationship between P50 and mortality was largely mediated by extrapulmonary organ dysfunction. A high P50 value at the time of PARDS diagnosis may be associated with mortality via dysfunctional extrapulmonary organs. Future studies should consider P50 as a potential candidate index for risk stratification of PARDS patients.
Digital reconstruction of infraslow activity in human intracranial ictal recordings using a deconvolution-based inverse filter
Authors: Lee Somin , Henry Julia , Tryba Andrew K. , Esengul Yasar , Warnke Peter , Wu Shasha , van Drongelen Wim
Published: August 2022

Infraslow activity (ISA) is a biomarker that has recently become of interest in the characterization of seizure recordings. Recent data from a small number of studies have suggested that the epileptogenic zone may be identified by the presence of ISA. Investigation of low frequency activity in clinical seizure recordings, however, has been hampered by technical limitations. EEG systems necessarily include a high-pass filter early in the measurement chain to remove large artifactual drifts that can saturate recording elements such as the amplifier. This filter, unfortunately, attenuates legitimately seizure-related low frequencies, making ISA difficult to study in clinical EEG recordings. In this study, we present a deconvolution-based digital inverse filter that allows recovery of attenuated low frequency activity in intracranial recordings of temporal lobe epilepsy patients. First, we show that the unit impulse response (UIR) of an EEG system can be characterized by differentiation of the system’s step response. As proof of method, we present several examples that show that the low frequency component of a high-pass filtered signal can be restored by deconvolution with the UIR. We then demonstrate that this method can be applied to biologically relevant signals including clinical EEG recordings obtained from seizure patients. Finally, we discuss how this method can be applied to study ISA to identify and assess the seizure onset zone.
The methodology of design of satellite working mechanism of positive displacement machine
Authors: Sliwinski Pawel
Published: August 2022

In this paper is described a methodology of design of satellite mechanism consisting of two non-circular gears (externally toothed rotor and internally toothed curvature) and circular gears (satellites). In the presented methodology is assumed that the rotor pitch line is known, and the curvature pitch line is necessary to designate. The presented methodology applies to mechanisms for which the number of the curvature humps is at least one greater than the number of rotor humps. The selection of the number of gears and the number of teeth in gear and rotor and curvature is also presented. The methodology of calculating the position of the satellite center and the angle of its rotation in order to shape the teeth on the rotor and curvature is presented. The article is also showed different types of satellite mechanisms—satellite mechanisms with the different numbers of humps on the rotor and curvature. The technical parameters of the mechanism for the rotor pitch line described by the cosine function are also presented.
Upconversion photoluminescence excitation reveals exciton–trion and exciton–biexciton coupling in hBN/WS$$_{2}$$/hBN van der Waals heterostructures
Authors: Żuberek Ewa , Majak Martyna , Lubczyński Jakub , Debus Joerg , Watanabe Kenji , Taniguchi Takashi , Ho Ching-Hwa , Bryja Leszek , Jadczak Joanna
Published: August 2022

Monolayers of transition-metal dichalcogenides with direct band gap located at the binary $$K_{-}/K_{+}$$

K
-

/

K
+

points of the Brillouin zone are promising materials for applications in opto- and spin-electronics due to strongly enhanced Coulomb interactions and specific spin-valley properties. They furthermore represent a unique platform to study electron–electron and electron–phonon interactions in diverse exciton complexes. Here, we demonstrate processes in which the neutral biexciton and two negative trions, namely the spin-triplet and spin-singlet trions, upconvert light into a bright intravalley exciton in an hBN-encapsulated WS$$_{2}$$

2

monolayer. We propose that the energy gains required in the polarized upconversion photoluminescence originate from different interactions including resonant optical phonons, a cooling of resident electrons and a non-local and an anisotropic electron–hole exchange, respectively. The temperature dependence (7–120 K) of the excitonic upconversion intensity obtained at excitation energies corresponding to the biexciton and trions provides insight into an increasing phonon population as well as a thermally enhanced electron scattering. Our study sheds new light on the understanding of excitonic spin and valley properties of van der Waals heterostructures and improves the understanding of photonic upconversion mechanisms in two-dimensional quantum materials.
Antiviral activity of natural phenolic compounds in complex at an allosteric site of SARS-CoV-2 papain-like protease
Authors: Srinivasan Vasundara , Brognaro Hévila , Prabhu Prince R. , de Souza Edmarcia Elisa , Günther Sebastian , Reinke Patrick Y. A. , Lane Thomas J. , Ginn Helen , Han Huijong , Ewert Wiebke , Sprenger Janina , Koua Faisal H. M. , Falke Sven , Werner Nadine , Andaleeb Hina , Ullah Najeeb , Franca Bruno Alves , Wang Mengying , Barra Angélica Luana C. , Perbandt Markus , Schwinzer Martin , Schmidt Christina , Brings Lea , Lorenzen Kristina , Schubert Robin , Machado Rafael Rahal Guaragna , Candido Erika Donizette , Oliveira Danielle Bruna Leal , Durigon Edison Luiz , Niebling Stephan , Garcia Angelica Struve , Yefanov Oleksandr , Lieske Julia , Gelisio Luca , Domaracky Martin , Middendorf Philipp , Groessler Michael , Trost Fabian , Galchenkova Marina , Mashhour Aida Rahmani , Saouane Sofiane , Hakanpää Johanna , Wolf Markus , Alai Maria Garcia , Turk Dusan , Pearson Arwen R. , Chapman Henry N. , Hinrichs Winfried , Wrenger Carsten , Meents Alke , Betzel Christian
Published: August 2022

SARS-CoV-2 papain-like protease (PLpro) covers multiple functions. Beside the cysteine-protease activity, facilitating cleavage of the viral polypeptide chain, PLpro has the additional and vital function of removing ubiquitin and ISG15 (Interferon-stimulated gene 15) from host-cell proteins to support coronaviruses in evading the host’s innate immune responses. We identified three phenolic compounds bound to PLpro, preventing essential molecular interactions to ISG15 by screening a natural compound library. The compounds identified by X-ray screening and complexed to PLpro demonstrate clear inhibition of PLpro in a deISGylation activity assay. Two compounds exhibit distinct antiviral activity in Vero cell line assays and one inhibited a cytopathic effect in non-cytotoxic concentration ranges. In the context of increasing PLpro mutations in the evolving new variants of SARS-CoV-2, the natural compounds we identified may also reinstate the antiviral immune response processes of the host that are down-regulated in COVID-19 infections.
Application and development of 3D bioprinting in cartilage tissue engineering
Authors: Li Mingyang , Sun Daocen , Zhang Juan , Wang Yanmei , Wei Qinghua , Wang Yanen
Published: August 2022

Bioprinting technology can build complex tissue structures and has the potential to fabricate engineered cartilage with bionic structures for achieving cartilage defect repair/regeneration.
Hijacking the intrinsic vitamin B12 pathway for the oral delivery of nanoparticles, resulting in enhanced in vivo anti-leishmanial activity
Authors: Singh Aakriti , Yadagiri Ganesh , Javaid Aaqib , Sharma Krishna Kumar , Verma Anurag , Singh Om Prakash , Sundar Shyam , Mudavath Shyam Lal
Published: August 2022

VBS-AmB-SLN as a stable oral anti-leishmanial carrier.
Understanding the facet effects of heterogeneous Rh2P catalysts for styrene hydroformylation
Authors: Liu Boyang , Wang Yu , Liu Shaoxiong , Kang Zhenyu , Lan Xiaocheng , Wang Tiefeng
Published: August 2022

Rh2P (111) facets are much more active than the other facets for heterogeneous hydroformylation.
The effect of outer-sphere anions on the spectroscopic response of metal-binding chemosensors
Authors: Ihde Michael H. , Covey Gabrielle , Johnson Ashley D. G. , Fronczek Frank R. , Wallace Karl J. , Bonizzoni Marco
Published: August 2022

The competition for the metal between outer-sphere anions and a fluorescent single-site ligand leads to sensing ion pairs in solution.
Catalytic activity, water resistance and stability of hematite nanomaterials in oxidative removal of polychlorinated aromatic hydrocarbons can be simultaneously enhanced through facet engineering
Authors: Ma Xiaodong , Liu Xiaoyao , Guo Haiwei , Ren Gengbo , Wen Jiaxin , Chen Wei , Wang Guichang
Published: August 2022

Catalytic activity, water resistance and stability of hematite nanomaterials in oxidative removal of polychlorinated aromatic hydrocarbons can be simultaneously enhanced through facet engineering.
Evaluation of the effect of a cell penetrating peptide (TAT) towards tailoring the targeting efficacy and tumor uptake of porphyrin
Authors: Guleria Mohini , Suman Shishu K. , Kumar Naveen , Sharma Amit K. , Amirdhanayagam Jeyachitra , Sarma Haladhar D. , Satpati Drishty , Das Tapas
Published: August 2022

Demonstration of the effect of conjugation of a cell penetrating peptide towards enhancing the in vitro and in vivo tumor targeting potential of porphyrin derivatives.
Post-polymerisation approaches for the rapid modification of conjugated polymer properties
Authors: Rimmele Martina , Glöcklhofer Florian , Heeney Martin
Published: August 2022

We summarise chemical approaches to modify the properties of conjugated polymers by post-polymerisation functionalisation directly on the backbone.
Morphological transition and transformation of 2D nanosheets by controlling the balance of π–π stacking interaction and crystalline driving forces
Authors: Li Heng , Han Liang , Zhu Yulin , Zheng Nan , Lai Hanjian , Fernández-Trillo Paco , He Feng
Published: August 2022

A series of PPV-TIPS-b-P2VP BCPs have been designed and synthesized, and the morphology transition from 2D square to rectangular or rod-like micelles was achieved. Heterogenous co-assembly was also realized as new circle-like micelles.
A highly efficient polydopamine encapsulated clinical ICG theranostic nanoplatform for enhanced photothermal therapy of cervical cancer
Authors: Du Zhong , Ma Rong , Chen Shuang , Fan Huimin , Heng Youqiang , Yan Ting , Alimu Gulinigaer , Zhu Lijun , Zhang Xueliang , Alifu Nuernisha , Ma Cailing
Published: August 2022

Photothermal therapy (PTT) is a safe and efficient anti-tumor treatment.
Enhanced photovoltaic performance of donor polymers effected by asymmetric π-bridges
Authors: Zhong Tian , Xiao Cong , Xiao Biao , Hu Liwen , Li Zhiya , Guo Feng , Wang Xunchang , Zhang Mingrui , Lei Shiyun , Yang Renqiang
Published: August 2022

Asymmetric π-bridge-based donor polymers produced via a simple one-pot chemical synthesis method exhibit enhanced photovoltaic performance.
Catalytic asymmetric cyclopropanation of sulfoxonium ylides catalyzed by a chiral-at-metal rhodium complex
Authors: Ming Siliang , Yang Jian , Wu Shi , Yao Gang , Xiong Hongwei , Du Yu , Gong Jun
Published: August 2022

An efficient asymmetric cyclopropanation of sulfoxonium ylides with α,β-unsaturated 2-acyl imidazoles catalyzed by a chiral-at-metal rhodium complex has been developed.
Vibrational spectroscopy investigation of defects in Zr- and Hf-UiO-66
Authors: Yost Brandon T. , Gibbons Bradley , Wilson Addison , Morris Amanda J. , McNeil L. E.
Published: August 2022

Missing cluster defects in Hf-UiO-66 cause a redshift of a distinct peak in the Raman spectrum.
Correction: Highly selective acid-catalyzed olefin isomerization of limonene to terpinolene by kinetic suppression of overreactions in a confined space of porous metal–macrocycle frameworks
Authors: He Wei , Tashiro Shohei , Shionoya Mitsuhiko
Published: August 2022

Correction for ‘Highly selective acid-catalyzed olefin isomerization of limonene to terpinolene by kinetic suppression of overreactions in a confined space of porous metal–macrocycle frameworks’ by Wei He et al., Chem. Sci., 2022, 13, 8752–8758, https://doi.org/10.1039/d2sc01561g.
Correction: Enzyme-powered micro- and nano-motors: key parameters for an application-oriented design
Authors: Arqué Xavier , Patiño Tania , Sánchez Samuel
Published: August 2022

Correction for ‘Enzyme-powered micro- and nano-motors: key parameters for an application-oriented design’ by Xavier Arqué et al., Chem. Sci., 2022, https://doi.org/10.1039/d2sc01806c.
In situ thermal exclusion induced Sb and Sb-doped SnO2 nanoheterostructuring and its improvements in cycling stabilities and rate capacities for Na+ storage
Authors: Guo Liping , Jiang Zhong-Jie , Wang Yongjie , Jiang Zhongqing
Published: August 2022

An in situ thermal exclusion approach is reported for the synthesis of carbon coated Sb-ATO hetero-NPs deposited on MWCNTs. The specific structure endows it with superior rate capacities and excellent cycling stabilities towards Na+ storage.
Exploration of biomimetic poly(γ-benzyl-l-glutamate) fibrous scaffolds for corneal nerve regeneration
Authors: Ma Tien-Li , Yang Shang-Chih , Cheng Ting , Chen Mei-Yun , Wu Jo-Hsuan , Liao Shu-Lang , Chen Wei-Li , Su Wei-Fang
Published: August 2022

Poly(γ-benzyl-l-glutamate) (PBG) made biomimetic scaffold is explored as candidate material for corneal nerve regeneration and neurotrophic keratopathy treatment.
Copper halide anion engineering for p-channel electrolyte-gated transistors with superior operational reliability
Authors: Lee Da In , Kim Min Su , Cho Kyung Gook , Hong Kihyon , Lee Keun Hyung
Published: August 2022

An effective strategy for improving the operational stability of solution-processed inorganic p-channel transistors has been demonstrated by doping copper iodide (CuI) semiconductor with nonvolatile bromine (Br).
Effect of Video Augmentative and Alternative Communication Technology on Communication During Play With Peers for Children With Autism Spectrum Disorder
Authors: Laubscher Emily , Barwise Allison , Light Janice
Published: August 2022

Purpose:

Children with autism spectrum disorder (ASD) are at risk for exclusion from play with their peers due to difficulty with communication skills. Video augmentative and alternative communication (AAC) technology has the potential to support communication within the context of play using videos with integrated visual scene displays. This study investigated the effect of a video AAC intervention on the number of turns in which children with ASD demonstrated symbolic communication during interactions with a peer without disabilities. Maintenance of skills, generalization to untrained play scenarios, and stakeholder perceptions of the video AAC technology were also investigated.

Method:

This study used a single-case, multiple-probe design across participant dyads. It included baseline, intervention, maintenance, and generalization phases. Six children with ASD and six peers participated in the study.

Results and Conclusions:

All six participants with ASD demonstrated an increase in the number of turns in which they demonstrated at least one symbolic communication act following intervention, although one participant demonstrated variability in baseline performance, making it difficult to draw conclusions. Results provide preliminary evidence that instruction with video AAC technology can support communication for children with ASD during play interactions with peers.
Radio detection of chemically peculiar stars with LOFAR
Authors: Hajduk Marcin , Leto Paolo , Vedantham Harish , Trigilio Corrado , Haverkorn Marijke , Shimwell Timothy , Callingham Joseph R. , White Glenn J.
Published: August 2022

Context. Chemically peculiar stars are upper main sequence stars that show anomalies in their optical spectra. These anomalies suggest peculiar chemical abundances of certain elements. Some chemically peculiar stars possess strong magnetic fields. Electrons originating from the ionising stellar wind travel in the magnetosphere of the star and become the source of non-thermal radio and X-ray emission. Several chemically peculiar radio stars have been detected at GHz frequencies.

Aims. We used the Low-Frequency Array (LOFAR) to search for radio emission from chemically peculiar stars to constrain their emission in the frequency band 120–168 MHz. We aimed to use LOFAR observations to test the models for radio emission of chemically peculiar stars.

Methods. We performed a targeted search of known chemically peculiar stars in the fields of the LOFAR Two Metre Survey (LoTSS) Data Release 2 in Stokes I and V. We matched positions of radio sources in the LoTSS-DR2 catalogue with positions of chemically peculiar stars.

Results. We report non-thermal emission at 120–168 MHz from two chemically peculiar stars in Stokes I, BP Boo, and α2 CVn. The ensuing incidence rate at these frequencies is significantly lower than for higher frequencies. This results from the turnover at low frequencies which was predicted from the theory of radio emission from chemically peculiar stars. BP Boo is detected for the first time at radio wavelengths, while α2 CVn had already been detected at higher frequencies. The upper limit of V/I indicates a level of circular polarisation significantly below 60%. We combined data obtained at different frequencies to derive the radio spectrum of α2 CVn. The spectrum is nearly flat beyond turnover at low frequencies. We modelled radio emission for a large magnetosphere and small local magnetic field strength. The amplitude of variation in radio emission with the rotational phase of the system decreases at low frequencies.
Is ozone a reliable proxy for molecular oxygen?
Authors: Kozakis Thea , Mendonça João M. , Buchhave Lars A.
Published: August 2022

Molecular oxygen (O2) paired with a reducing gas is regarded as a promising biosignature pair for the atmospheric characterization of terrestrial exoplanets. In circumstances when O2 may not be detectable in a planetary atmosphere (e.g., at mid-IR wavelengths) it has been suggested that ozone (O3), the photochemical product of O2, could be used as a proxy to infer the presence of O2. However, O3 production has a nonlinear dependence on O2 and is strongly influenced by the UV spectrum of the host star. To evaluate the reliability of O3 as a proxy for O2, we used Atmos, a 1D coupled climate and photochemistry code, to study the O2–O3 relationship for “Earth-like” habitable zone planets around a variety of stellar hosts (G0V-M5V) and O2 abundances. Overall, we found that the O2–O3 relationship differed significantly with stellar hosts and resulted in different trends for hotter stars (G0V-K2V) versus cooler stars (K5V-M5V). Planets orbiting hotter host stars counter-intuitively experience an increase in O3 when O2 levels are initially decreased from 100% Earth’s present atmospheric level (PAL), with a maximum O3 abundance occurring at 25–55% PAL O2. As O2 abundance initially decreases, larger amounts of UV photons capable of O2 photolysis reach the lower (denser) regions of the atmosphere where O3 production is more efficient, thus resulting in these increased O3 levels. This effect does not occur for cooler host stars (K5V-M5V), since the weaker incident UV flux does not allow O3 formation to occur at dense enough regions of the atmosphere where the faster O3 production can outweigh a smaller source of O2 from which to create O3. Thus, planets experiencing higher amounts of incident UV possessed larger stratospheric temperature inversions, leading to shallower O3 features in planetary emission spectra. Overall it will be extremely difficult (or impossible) to infer precise O2 levels from an O3 measurement, however, with information about the UV spectrum of the host star and context clues, O3 will provide valuable information about potential surface habitability of an exoplanet.
La myologie en temps de guerre…
Authors: Andoni Urtizberea J.
Published: August 2022

Plusieurs spécialistes français en pathologie neuromusculaire ont établi des liens forts de coopération avec leurs homologues de Russie et d’Ukraine. Les Cahiers de Myologie s’en sont d’ailleurs fait l’écho à plusieurs reprises.
Zelltherapie in den Zeiten von SARS-CoV-2
Authors: Wiercinska Eliza , Bönig Halvard
Published: August 2022

Ein breites Spektrum von Disruptionen, aber auch blitzschnelle Innovationen, hat
die SARS-CoV-2 Pandemie gebracht. Dieser Übersichtsartikel betrachtet
die Pandemie aus der Warte der Zelltherapie; konkret werden vier Aspekte
untersucht: Wie unterscheiden sich die Risiken von Zelltherapie-Patienten mit
SARS-CoV-2 Infektion und COVID von denen der Allgemeinbevölkerung? Sind
Empfänger von Zelltherapien, hier speziell autologe und allogene
Stammzelltransplantationsempfänger sowie Empfänger von
CAR-T-Zell-Präparaten, klinisch relevant durch SARS-CoV-2 Vakzine
immunisierbar? Welche Auswirkungen hat die Pandemie mit Spenderausfallrisiko und
Zusammenbruch von Supply Chains auf die Versorgung mit Zelltherapeutika? Gibt es
Zelltherapeutika, die bei schwerem COVID therapeutisch nutzbringend eingesetzt
werden können? In aller Kürze, das erwartete massiv
erhöhte Risiko von Zelltherapie-Patienten, im Infektionsfall einen
schweren Verlauf zu erleiden oder zu sterben, wurde bestätigt. Die
Vakzine induziert jedoch bei vielen dieser Patienten humorale und
zelluläre Immunität, wenn auch weniger zuverlässig als
bei Gesunden. Dank kreativer Lösungen gelang es, die Versorgung mit
Zelltherapeutika im Wesentlichen uneingeschränkt aufrecht zu erhalten.
SARS-CoV-2-spezifische T-Zell-Präparate für den adoptiven
Immuntransfer wurden entwickelt, eine therapeutische Konstellation diese
anzuwenden ergab sich jedoch nicht. Therapiestudien mit mesenchymalen
Stromazellen beim schweren COVID laufen weltweit; die Frage der Wirksamkeit
bleibt zurzeit offen, bei jedoch substanziellem Optimismus in der Szene. Einige
der Erkenntnisse und Innovationen aus der SARS-CoV-2-Pandemie können
möglicherweise verallgemeinert werden und so auf die Zeit nach ihrem
Ende langfristig nachwirken.
Subepithelial tumors: How does endoscopic full-thickness resection & submucosal tunneling with endoscopic resection compare with laparoscopic endoscopic cooperative surgery?
Authors: Kahaleh Michel , Bhagat Vicky , Dellatore Peter , Tyberg Amy , Sarkar Avik , Shahid Haroon M. , Andalib Iman , Alkhiari Resheed , Gaidhane Monica , Kedia Prashant , Nieto Jose , Kumta Nikhil A. , Dixon Rebekah E. , Salameh Habeeb , Mavrogenis Georgios , Bassioukas Stefanos , Abe Seiichiro , Arentes Vitor N. , Morita Flavio H. , Sakai Paulo , de Moura Eduardo G.
Published: August 2022

Background and study aims Endoscopic techniques are rapidly emerging for resection of subepithelial tumors (SETs). Submucosal tunneling for endoscopic resection (STER), endoscopic full-thickness resection (EFTR) and laparoscopic endoscopic cooperative surgery (LECS) are current alternatives to open surgery. In this study, we aimed to compare the three endoscopic techniques.

Patients and methods Consecutive patients who underwent resection of a submucosal esophageal or gastric lesion at several tertiary care centers were included in a dedicated registry over 3 years. Demographics, size and location of resected lesion, histology of specimen, length of procedure, adverse events (AEs), duration of hospital stay, and follow-up data were collected.

Results Ninety-six patients were included (47.7 % male, mean age 62): STER n = 34, EFTR n = 34, LECS n = 280. The lesions included leiomyoma, gastrointestinal stromal tumors (GISTs) and other. The mean lesion size was 28 mm (STD 16, range 20–72 mm). The majority of lesions in the EFTR and laparoscopic-assisted resection group were GISTs. There was no significant difference in clear resection margins, post-procedure complication rates, recurrence rate and total follow-up duration between the groups. However, the LECS group had a procedure time at least 30 minutes longer than STER or EFTR (P < 0.01). Total hospital stay for the laparoscopic-assisted resection group was also longer when compared to STER (1.5) and EFTR (1.8) (P < 0.01).

Conclusions STER, EFTR, and laparoscopic-assisted resection are efficacious approaches for resection of SETs with similar R0 resection rates, complication rates, and AE rates. Laparoscopic assisted resection appears more time-consuming and is associated with a longer hospital stay.
Optimization of Methyl Anthranilate Synthesis Process by Response Surface Methodology and Its Reaction Mechanism
Authors: Du Lei , Wang Ben , Diao Yanwei , Yuan Jinqiu , Zhang Fuyue , Zhou Haoyu
Published: August 2022

In this paper, a unique process for the production of methyl anthranilate (MA) was investigated. The factors of the phthalimide/sodium hypochlorite/methanol molar ratio, reaction temperature, hydrolysis temperature, and water consumption on the yield and purity of MA were analyzed. Response surface methodology (RSM) was used to optimize conditions for the semi-batch synthesis process of MA. The best synthetic conditions for the formation of MA were reaction temperature 0.5 °C, hydrolysis temperature 70 °C and n(phthalimide)/n(sodium hypochlorite)/n(methanol) = 1:2.03:5.87, and water consumption m(H2O)/m(phthalimide) = 7.16:1. The yield of MA could reach 90% under the optimal conditions, which is more than 10% higher than that of the previous semi-batch process. Furthermore, the reaction mechanism was investigated by infrared spectroscopy analysis, and the mechanism of ester group formation and the structure of intermediate products are proposed. The byproduct of the reaction was studied by GC-MS analysis, a byproduct called 2-cyanobenzoic acid has been discovered. Therefore, an unprecedented reaction mechanism of the whole synthesis process is proposed.
The future of education utilizing artificial intelligence in Turkey
Authors: İçen Mustafa
Published: August 2022

This study examined the potential effects of artificial intelligence on Turkish education. A qualitative research approach was employed by posing an open-ended question to academics in order to attain this objective thanks to built-in capabilities for conducting complicated computer operations, cloud-based services, and conciliatory accession for agile network connections. This study emphasizes that Turkey is highly fragmented and consists of various business organizations at both the municipal and regional levels. The two main policy documents produced by the Turkish government suggest that colleges play a strong role in national and regional Artificial Intelligence (AI) strategies for workforce growth, with substantial consequences for AI adoption strategies. These documents include information on three well-known educational entities: The new oriental workgroups, recurrent neural networks, and classroom clustering. Significant aspects of Turkey’s educational AI growth include a strong private education industry and a growing international interest. The investigation results revealed a decline in the level of understanding regarding the methods of using artificial intelligence, indicating the necessity for additional awareness-raising in Turkey.
Breaking the electric field barrier in microelectronics
Authors: Lim Alane
Published: August 2022

Incorporating vacuum gaps in semiconductor devices enables the integration of extremely high electric fields.
Thermal transport in 3D printed shape memory polymer metamaterials
Authors: Farzinazar Shiva , Wang Yueping , Abdol-Hamid Owens Charles , Yang Chen , Lee Howon , Lee Jaeho
Published: August 2022

Shape memory polymers are gaining significant interest as one of the major constituent materials for the emerging field of 4D printing. While 3D-printed metamaterials with shape memory polymers show unique thermomechanical behaviors, their thermal transport properties have received relatively little attention. Here, we show that thermal transport in 3D-printed shape memory polymers strongly depends on the shape, solid volume fraction, and temperature and that thermal radiation plays a critical role. Our infrared thermography measurements reveal thermal transport mechanisms of shape memory polymers in varying shapes from bulk to octet-truss and Kelvin-foam microlattices with volume fractions of 4%–7% and over a temperature range of 30–130 °C. The thermal conductivity of bulk shape memory polymers increases from 0.24 to 0.31 W m−1 K−1 around the glass transition temperature, in which the primary mechanism is the phase-dependent change in thermal conduction. On the contrary, thermal radiation dominates heat transfer in microlattices and its contribution to the Kelvin-foam structure ranges from 68% to 83% and to the octet-truss structure ranges from 59% to 76% over the same temperature range. We attribute this significant role of thermal radiation to the unique combination of a high infrared emissivity and a high surface-to-volume ratio in the shape memory polymer microlattices. Our work also presents an effective medium approach to explain the experimental results and model thermal transport properties with varying shapes, volume fractions, and temperatures. These findings provide new insights into understanding thermal transport mechanisms in 4D-printed shape memory polymers and exploring the design space of thermomechanical metamaterials.
In transcription antitermination by Qλ, NusA induces refolding of Qλ to form a nozzle that extends the RNA polymerase RNA-exit channel
Authors: Yin Zhou , Bird Jeremy G. , Kaelber Jason T. , Nickels Bryce E. , Ebright Richard H.
Published: August 2022

Lambdoid bacteriophage Q proteins are transcription antipausing and antitermination factors that enable RNA polymerase (RNAP) to read through pause and termination sites. Q proteins load onto RNAP engaged in promoter-proximal pausing at a Q binding element (QBE) and adjacent sigma-dependent pause element to yield a Q-loading complex, and they translocate with RNAP as a pausing-deficient, termination-deficient Q-loaded complex. In previous work, we showed that the Q protein of bacteriophage 21 (Q21) functions by forming a nozzle that narrows and extends the RNAP RNA-exit channel, preventing formation of pause and termination RNA hairpins. Here, we report atomic structures of four states on the pathway of antitermination by the Q protein of bacteriophage λ (Qλ), a Q protein that shows no sequence similarity to Q21 and that, unlike Q21, requires the transcription elongation factor NusA for efficient antipausing and antitermination. We report structures of Qλ, the Qλ-QBE complex, the NusA-free pre-engaged Qλ-loading complex, and the NusA-containing engaged Qλ-loading complex. The results show that Qλ, like Q21, forms a nozzle that narrows and extends the RNAP RNA-exit channel, preventing formation of RNA hairpins. However, the results show that Qλ has no three-dimensional structural similarity to Q21, employs a different mechanism of QBE recognition than Q21, and employs a more complex process for loading onto RNAP than Q21, involving recruitment of Qλ to form a pre-engaged loading complex, followed by NusA-facilitated refolding of Qλ to form an engaged loading complex. The results establish that Qλ and Q21 are not structural homologs and are solely functional analogs.
The translator as rereader
Authors: Ray Sohomjit
Published: August 2022

A. K. Ramanujan’s complicated invocations of fidelity in the paratexts of his pioneering translations have invited analyses that focus on contradictions and paradoxes in his translation theory and practice. Providing a brief historical overview of translation in the South Asian context, this article contextualizes fidelity as a colonial remnant produced due to Ramanujan’s need to move between two disparate models of translation. Emphasizing Ramanujan’s identity as a poet-translator, I claim that his translation practice should be seen to have a poetics of its own; the impression of contradiction or paradox is resolved and the colonial remnant of fidelity decentralized if we consider this poetics to be a deeply hermeneutic act. I describe Ramanujan’s translation poetics to be defined by rereading, such that the translator is not just a reader nor fully a writer, but one who straddles both roles with ease to exist in community with other readers.
Pressure induced structural phase transition in Cr doped Mn2O3 multiferroics
Authors: Chandra Mohit , Yadav Satish , Srihari Velaga , Poswal Himanshu Kumar , Rawat Rajeev , Singh Kiran
Published: August 2022

The pressure dependent structural properties of polycrystalline Mn2−xCrxO3 (x = 0, 0.01, 0.05) multiferroics have been investigated using synchrotron x-ray diffraction (SXRD) measurements up to 41 GPa at room temperature (RT). Our results illustrate that irrespective of their RT crystal structure, all the studied samples undergo pressure induced structural phase transition to monoclinic phase. For pristine Mn2O3, the phase transition starts around 20.8 GPa and completely transformed to monoclinic phase around 37 GPa during compression. The co-existence of orthorhombic and monoclinic phase persists at wide pressure range i.e. 20.8 to 37 GPa. The Cr substitutions lower the required pressure for pressure induced phase transition i.e. for x = 0.01 and x = 0.05, Cr doped samples, the pressure induced phase transition occurs at 35 GPa and 33 GPa, respectively. These transitions are reversible (with hysteresis) during decompression and remained unquenchable under pressure. These results corroborate that Cr substitution modify the RT crystal structure and induces positive chemical pressure in Mn2O3.
Charmless two-body B meson decays in the perturbative QCD factorization approach*
Authors: Chai Jian , Cheng Shan , Ju Yao-hui , Yan Da-Cheng , Lü Cai-Dian , Xiao Zhen-Jun
Published: August 2022

The perturbative quantum chromodynamics (PQCD) approach based on

factorization has resulted in great achievements in the QCD calculation of hadronic B decays. By regulating the endpoint divergence by the transverse momentum of quarks in the propagators, one can perform the perturbation calculation for various diagrams, including annihilation type diagrams. In this paper, we review the current status of the PQCD factorization calculation of two-body charmless

U decays up to next-to-leading order (NLO) QCD corrections. Two new power suppressed terms in the decaying amplitudes are also considered. Using universal input (non-perturbative) parameters, we collect the branching ratios and

asymmetry parameters of all charmless two body B decays, which are calculated in the PQCD approach up to NLO. The results are compared with those of the QCD factorization approach, soft-collinear effective theory approach, and current experimental measurements. For most of the considered B meson decays, the PQCD results for branching ratios agree well with those of other approaches and experimental data. The PQCD predictions for the

asymmetry parameters of many of the decay channels do not agree with those of other approaches but have better agreement with experimental data. The longstanding

puzzle regarding the pattern of the direct CP asymmetries of penguin-dominated

decays can be understood after the inclusion of NLO contributions in PQCD. The NLO corrections and power suppressed terms play an important role in color suppressed and pure annihilation type B decay modes. These rare decays are more sensitive to different types of corrections, providing an opportunity to examine the factorization approach with more precise experimental measurements.
Smart Airport: Mobile Asset Information Modeling Management based on Gamificative VR Environment --- A Case Study of Ningbo Lishe International Airport Staff Restaurant
Authors: Kong Dezhou , Kapogiannis Georgios , Cheshmehzangi Ali
Published: August 2022

With the popularization of Virtual Reality (VR) technology, the application of the complementary advantages of BIM+VR collaboration in facility management (FM) and asset management (AM) is an emerging research field. This theory holds that BIM information generated and acquired in the life cycle of the facility can improve the management of the facility and asset based on the visual expression of VR technology. With this proposition as a starting point, based on the Ningbo Lishe International Airport’s staff restaurant project, the purpose of this paper is to investigate the value of BIM and VR and the challenges they pose in influencing their adoption in AM applications. By establishing a BIM model and a quantitative asset information model, and using the 720 cloud VR platform and related smart devices to complete the visual expression of asset information. The results demonstrated that that the value of BIM+VR in AM comes from the improvement of the existing manual information transfer process, which reduces the data delay to a large extent. Secondly, the accuracy and accessibility of AM data are improved, and the efficiency of the management is improved. The originality of this paper is to prove the great potential of BIM and VR in AM optimization and improvement through real case study, and to provide empirical evidence for the value and challenges of BIM+VR in AM application.
Effect of lemon juice as an eco-friendly additive on the microstructure and corrosion properties of anodized alumina layers
Authors: Hasanpour Jalal , Azadi Mahboobeh , Mohri Maryam
Published: August 2022

The challenge of anodizing processes is to decrease the chromate compounds or other poisonous materials from the anodizing bath in a way that the performance of oxide layers does not change. Therefore, in this study, a new anodizing bath was developed to create the alumina layers. The new bath contained an H2SO4solution with an eco-friendly additive. This additive was lemon juice (which contained natural citric acid) at various concentrations (0.3 to 2.5 vol%). Field-emission scanning electron microscopy (FESEM) was used to investigate the microstructural evaluations. Tafel polarization and electrochemical impedance spectroscopy (EIS) were also utilized to study the corrosion behavior of the alumina layers on aluminum substrates. The obtained results depicted that the presence of the bio-additive in the anodizing bath caused a reduction in corrosion rates of alumina layers by approximately 90.2 to 100% compared to the layer manufactured without additive. EIS measurements showed an increase in impedance of modified alumina layers by approximately 46%–71% in 0.6 M NaCl solution. Optimum corrosion properties were related to the modified alumina layer when the additive concentration in the anodizing bath was approximately 1.8 vol%. Since it contained low porosity with a value of 3.8% and a thick barrier layer with a thickness of 21 nm.
Ti3C2T
x
MXene anchoring semi-metallic selenium atoms: self-powered photoelectrochemical-type photodetector, hydrogen evolution, and gas-sensing applications
Authors: Azadmanjiri Jalal , Roy Pradip Kumar , Děkanovský Lukáš , Regner Jakub , Sofer Zdeněk
Published: August 2022

MXenes have demonstrated substantial promise as photocatalysts and electrocatalysts for a variety of applications such as self-powered photoelectrochemical (PEC)-type photodetector, hydrogen evolution reaction (HER), and vapor sensing applications. However, their mechanism is still poorly figured out. Currently, Ti3C2T
x
MXene suffers from low photoresponsivity, high overpotential, and low sensitivity in such important applications. In order to develop catalytic activity and performances of those devices, modifications must be made to the structure of MXenes to enhance the separation of photogenerated charges, rate of the H+/e− couplings, and surface-active sites. These manipulations of MXenes heavily depend on understanding the mechanism of devices, appropriate modification elements, and the method of modification. This study for the first time reveals a facile solid-state annealing strategy for doping semi-metallic selenium (Se) atoms on Ti3C2T
x
MXene for self-powered PEC-type photodetector, HER, and vapor sensor applications. The suitable characteristics of Ti3C2T
x
make it an appropriate substrate to accommodate Se atoms. The well-designed Se-doped Ti3C2 heterojunction including some TiO2 cuboids could exhibit unprecedented photoresponsivity (up to 90 mA W−1) and detectivity (up to 2.0 × 108 cm Hz1/2 W−1) for 420 nm light, HER (−0.7 V at 10 mA cm−2), and gas sensitivity (Z′ = 347 Ω and Z′′ = 150 Ω, for ethanol) in comparison with the pristine Ti3C2T
x
nanosheets. The acquired promising results can be promoted with some other elements and also be examined in other electrolytes. Then, bring inspiration to the applications involving charge transfer, H+/e− couplings, and surface-active sites.
Highly sensitive stretchable sensor combined with low-power memristor for demonstration of artificial mechanoreceptor properties
Authors: Papakonstantinopoulos Charalampos , Bousoulas Panagiotis , Aslanidis Evangelos , Skotadis Evangelos , Tsigkourakos Menelaos , Tsoukalas Dimitris
Published: August 2022

The development of high-performance sensors emulating the response of the human skin to external mechanical stimuli is of increasing importance in the era of artificial intelligence and robotics. To realize artificial skin, various parameters must be met, including flexibility, biocompatibility and low power consumption of the employed sensors. In parallel, a multisensory platform for both detection and storage is required for emulating the physical properties of human skin. With this in mind, in this work we demonstrate an extremely sensitive resistive stretchable sensor that can achieve a gauge factor of ∼107 based on the employment of a polydimethylsiloxane (PDMS) substrate decorated with Pt nanoparticles as the stretch-sensitive medium placed in between two Ag electrodes. A critical step to achieve such performance is the formation of a rippled surface of the PDMS substrate through the combined use of pre-stretch and the deposition of a thin Al2O3 film by atomic layer deposition that enables the fabrication of highly stretchable Ag electrodes. The wavelength of the ripples, as well as the peak-to-valley height between them, can be directly controlled by tuning the applied pre-stretch load on the PDMS. By taking advantage of the extreme sensor sensitivity achieved, emulation of the functionality of a biological mechanoreceptor was further demonstrated by connecting the sensor in a parallel circuit configuration with a SiO2-based conductive-bridge memory. Various synaptic properties of the above sensory system are demonstrated, including paired-pulse facilitation and long-term plasticity, indicating the capabilities of our system to perform neuromorphic computations at the edge.
Propagation of errors and quantitative quantum simulation with quantum advantage
Authors: Flannigan S , Pearson N , Low G H , Buyskikh A , Bloch I , Zoller P , Troyer M , Daley A J
Published: August 2022

The rapid development in hardware for quantum computing and simulation has led to much interest in problems where these devices can exceed the capabilities of existing classical computers and known methods. Approaching this for problems that go beyond testing the performance of a quantum device is an important step, and quantum simulation of many-body quench dynamics is one of the most promising candidates for early practical quantum advantage. We analyse the requirements for quantitatively reliable quantum simulation beyond the capabilities of existing classical methods for analogue quantum simulators with neutral atoms in optical lattices and trapped ions. Considering the primary sources of error in analogue devices and how they propagate after a quench in studies of the Hubbard or long-range transverse field Ising model, we identify the level of error expected in quantities we extract from experiments. We conclude for models that are directly implementable that regimes of practical quantum advantage are attained in current experiments with analogue simulators. We also identify the hardware requirements to reach the same level of accuracy with future fault-tolerant digital quantum simulation. Verification techniques are already available to test the assumptions we make here, and demonstrating these in experiments will be an important next step.
Reflected impedanceometry: a contact-free technique for measuring induced magnetic hysteresis and eddy current heating
Authors: Noble Jonathan P P , Hill Alfred K
Published: August 2022

Reflected Impedanceometry is a new technique that can remotely measure the power absorbed during radiofrequency induction heating. It measures the total system impedance from the phase difference between current and voltage in the electromagnetic field work coil and uses the characteristic impedance of the work coil circuit to infer the heating power transferred into a susceptor bed. Induction heating of susceptor materials within alternating magnetic fields occurs by magnetic hysteresis, eddy currents, Néel relaxation or Brownian relaxation. It shows potential for replacing fossil fuels with renewable electricity in carbon-intensive industrial applications but requires advances in measurement techniques. Previously developed methods for measuring heating power, such as pick-up coils, are limited to applications involving magnetic materials. Results presented here show that reflected impedanceometry accurately measures heating power for both magnetic hysteresis and eddy currents, fulfilling the requirement for measuring induction heating power.
Embedding ℚ into a finitely presented group
Authors: Belk James , Hyde James , Matucci Francesco
Published: August 2022

We observe that the group of all lifts of elements of Thompson’s group 

T
T

to the real line is finitely presented and contains the additive group 

Q

\mathbb {Q}

of the rational numbers. This gives an explicit realization of the Higman embedding theorem for 

Q

\mathbb {Q}

, answering a Kourovka notebook question of Martin Bridson and Pierre de la Harpe.