bluuebunny/crossref_metadata_2025 huggingface dataset:
Modeling Patterns of Land Use in Chinese Cities Using an Integrated Cellular Automata Model
Authors: Feng Yanlei , Qi Yi
Published: October 2018

This paper introduces an urban growth simulation model applied to the full scope of China. The model uses a multicriteria decision analysis to calculate the land conversion probability and then integrates it with a cellular automata model. A nonlinear relationship is incorporated in to the model to interpret the impacts of different Land Use and Cover Change driving forces. The Analytical Hierarchical Process is also implemented to compute the variance between weights of different factors. Multiple sizes of neighborhood and different urban ratios in the model rules are tested, and a 5 × 5 neighborhood and an urban threshold of 0.33 are chosen. The study demonstrates the importance of spatial analysis on socioeconomic factors, population, and Gross Domestic Product in land use change simulation modeling. The model fills the gap between the purely economic theory simulation model and the geographic simulation model. The nationwide urban simulation is an example that addresses the lack of urban simulation studies in China and among large-scale simulation models.
Overexpression of a Novel ROP Gene from the Banana (MaROP5g) Confers Increased Salt Stress Tolerance
Authors: Miao Hongxia , Sun Peiguang , Liu Juhua , Wang Jingyi , Xu Biyu , Jin Zhiqiang
Published: October 2018

Rho-like GTPases from plants (ROPs) are plant-specific molecular switches that are crucial for plant survival when subjected to abiotic stress. We identified and characterized 17 novel ROP proteins from Musa acuminata (MaROPs) using genomic techniques. The identified MaROPs fell into three of the four previously described ROP groups (Groups II–IV), with MaROPs in each group having similar genetic structures and conserved motifs. Our transcriptomic analysis showed that the two banana genotypes tested, Fen Jiao and BaXi Jiao, had similar responses to abiotic stress: Six genes (MaROP-3b, -5a, -5c, -5f, -5g, and -6) were highly expressed in response to cold, salt, and drought stress conditions in both genotypes. Of these, MaROP5g was most highly expressed in response to salt stress. Co-localization experiments showed that the MaROP5g protein was localized at the plasma membrane. When subjected to salt stress, transgenic Arabidopsis thaliana overexpressing MaROP5g had longer primary roots and increased survival rates compared to wild-type A. thaliana. The increased salt tolerance conferred by MaROP5g might be related to reduced membrane injury and the increased cytosolic K+/Na+ ratio and Ca2+ concentration in the transgenic plants as compared to wild-type. The increased expression of salt overly sensitive (SOS)-pathway genes and calcium-signaling pathway genes in MaROP5g-overexpressing A. thaliana reflected the enhanced tolerance to salt stress by the transgenic lines in comparison to wild-type. Collectively, our results suggested that abiotic stress tolerance in banana plants might be regulated by multiple MaROPs, and that MaROP5g might enhance salt tolerance by increasing root length, improving membrane injury and ion distribution.
CEACAM1 in Liver Injury, Metabolic and Immune Regulation
Authors: Horst Andrea Kristina , Najjar Sonia M. , Wagener Christoph , Tiegs Gisa
Published: October 2018

Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) is a transmembrane glycoprotein that is expressed on epithelial, endothelial and immune cells. CEACAM1 is a differentiation antigen involved in the maintenance of epithelial polarity that is induced during hepatocyte differentiation and liver regeneration. CEACAM1 regulates insulin sensitivity by promoting hepatic insulin clearance, and controls liver tolerance and mucosal immunity. Obese insulin-resistant humans with non-alcoholic fatty liver disease manifest loss of hepatic CEACAM1. In mice, deletion or functional inactivation of CEACAM1 impairs insulin clearance and compromises metabolic homeostasis which initiates the development of obesity and hepatic steatosis and fibrosis with other features of non-alcoholic steatohepatitis, and adipogenesis in white adipose depot. This is followed by inflammation and endothelial and cardiovascular dysfunctions. In obstructive and inflammatory liver diseases, soluble CEACAM1 is shed into human bile where it can serve as an indicator of liver disease. On immune cells, CEACAM1 acts as an immune checkpoint regulator, and deletion of Ceacam1 gene in mice causes exacerbation of inflammation and hyperactivation of myeloid cells and lymphocytes. Hence, hepatic CEACAM1 resides at the central hub of immune and metabolic homeostasis in both humans and mice. This review focuses on the regulatory role of CEACAM1 in liver and biliary tract architecture in health and disease, and on its metabolic role and function as an immune checkpoint regulator of hepatic inflammation.
Deprotonation Mechanism of Methyl Gallate: UV Spectroscopic and Computational Studies
Authors: Zhang Liangliang , Liu Yuchen , Wang Yongmei
Published: October 2018

In the present paper, methyl gallate (MeG), a simple polyphenol and also the monomer of hydrolysable tannins, was selected to study the deprotonation process for the hydroxyls of the galloyl group by the combined use of spectroscopic measurements and quantum chemical calculations. The results of quantum chemical calculations show that the deprotonated form of methyl gallate undergoes the para-quinoid localization in the benzene ring, compared with free methyl gallate. The predicted spectra obtained from the free and deprotonated methyl gallate models are in agreement with the experimental UV-visible (UV-vis) absorption spectra. In the same way, the vibrational spectra of the para-quinoid MeG models validate the proposed mechanism of the deprotonation of MeG molecule. The pH influence on the deprotonation reaction and oxidization of phenolic groups has been also investigated. The pKa values of MeG were evaluated using the chemometric modeling method. The first acid dissociation constant (pKa1) for MeG was evaluated to be 4.20 ± 0.01, and the second one (pKa2) was 10.78 ± 0.06.
Hydrophilic Astragalin Galactoside Induces T Helper Type 1-Mediated Immune Responses via Dendritic Cells
Authors: Jeon Jae Hyoung , Lee Byung-Cheol , Kim Doman , Cho Daeho , Kim Tae Sung
Published: October 2018

A flavonoid Astragalin (kaempferol-3-O-β-d-glucopyranoside, Ast) has several biological activities including anti-oxidant, anti-HIV, and anti-allergic effects. Nonetheless, its insolubility in hydrophilic solvents imposes restrictions on its therapeutic applications. In this study, we investigated the effects of water-soluble astragalin-galactoside (kaempferol-3-O-β-d-isomaltotrioside, Ast-Gal) on murine bone marrow-derived dendritic cell (DC) maturation and T helper (Th) cell-mediated immune responses. Ast-Gal significantly increased maturation and activation of DCs through the upregulation of surface markers, such as cluster of differentiation (CD)80, CD86, and Major histocompatibility complex (MHC) II in a dose-dependent manner, while Ast had little effects. Additionally, Ast-Gal-treated DCs markedly secreted immune-stimulating cytokines such as interleukin (IL)-1β, IL-6, and IL-12. Importantly, Ast-Gal strongly increased expression of IL-12, a polarizing cytokine of Th1 cells. In a co-culture system of DCs and CD4+ T cells, Ast-Gal-treated DCs preferentially differentiates naïve CD4+ T cells into Th1 cells. The addition of neutralizing IL-12 monoclonal antibody (mAb) to cultures of Ast-Gal-treated DCs and CD4+ T cells significantly decreased interferon (IFN)-γ production, thereby indicating that Ast-Gal-stimulated DCs enhance the Th1 response through IL-12 production by DCs. Injection with Ast-Gal-treated DCs in mice increased IFN-γ-secreting Th1 cell population. Collectively, these findings indicate that hydrophilically modified astragalin can enhance Th1-mediated immune responses via DCs and point to a possible application of water-soluble astragalin-galactoside as an immune adjuvant.
Sex-Dependent Effects of Bmal1-Deficiency on Mouse Cerebral Cortex Infarction in Response to Photothrombotic Stroke
Authors: Lembach Anne , Stahr Anna , Ali Amira A. H. , Ingenwerth Marc , Von Gall Charlotte
Published: October 2018

Stroke is a leading cause of disability and death worldwide. There is increasing evidence that occurrence of ischemic stroke is affected by circadian system and sex. However, little is known about the effect of these factors on structural recovery after ischemic stroke. Therefore, we studied infarction in cerebral neocortex of male and female mice with deletion of the clock gene Bmal1 (Bmal1−/−) after focal ischemia induced by photothrombosis (PT). The infarct core size was significantly smaller 14 days (d) as compared to seven days after PT, consistent with structural recovery during the sub-acute phase. However, when sexes were analyzed separately 14 days after PT, infarct core was significantly larger in wild-type (Bmal1+/+) female as compared to male Bmal1+/+ mice, and in female Bmal1+/+, as compared to female Bmal1−/− mice. Volumes of reactive astrogliosis and densely packed microglia closely mirrored the size of infarct core in respective groups. Estradiol levels were significantly higher in female Bmal1−/− as compared to Bmal1+/+ mice. Our data suggests a sex-dependent effect and an interaction between sex and genotype on infarct size, the recruitment of astrocytes and microglia, and a relationship of these cells with structural recovery probably due to positive effects of estradiol during the subacute phase.
Emodin Sensitizes Hepatocellular Carcinoma Cells to the Anti-Cancer Effect of Sorafenib through Suppression of Cholesterol Metabolism
Authors: Kim Young-Seon , Lee Yoon-Mi , Oh Taek-In , Shin Dong Hoon , Kim Geon-Hee , Kan Sang-Yeon , Kang Hyeji , Kim Ji Hyung , Kim Byeong Mo , Yim Woo Jong , Lim Ji-Hong
Published: October 2018

Reduced therapeutic efficacy of sorafenib, a first-generation multikinase inhibitor, is often observed during the treatment of advanced hepatocellular carcinoma (HCC). Emodin is an active component of Chinese herbs, and is effective against leukemia, lung cancer, colon cancer, pancreatic cancer, and HCC; however, the sensitizing effect of emodin on sorafenib-based HCC therapy has not been evaluated. Here, we demonstrate that emodin significantly improved the anti-cancer effect of sorafenib in HCC cells, such as HepG2, Hep3B, Huh7, SK-HEP-1, and PLC/PRF5. Mechanistically, emodin inhibits sterol regulatory element-binding protein-2 (SREBP-2) transcriptional activity, which suppresses cholesterol biosynthesis and oncogenic protein kinase B (AKT) signaling. Additionally, attenuated cholesterol synthesis and oncogenic AKT signaling inactivated signal transducer and activator of transcription 3 (STAT3), an oncogenic transcription factor. Furthermore, emodin synergistically increased cell cycle arrest in the G1 phase and apoptotic cells in the presence of sorafenib. Animal models xenografted with HepG2 or SK-HEP-1 cells also showed that the combination of emodin and sorafenib was sufficient to inhibit tumor growth. Overall, these results suggested that the combination of emodin and sorafenib may offer a potential therapy for patients with advanced HCC.
MiR-371a-3p Serum Levels Are Increased in Recurrence of Testicular Germ Cell Tumor Patients
Authors: Terbuch Angelika , Adiprasito Jan B. , Stiegelbauer Verena , Seles Maximilian , Klec Christiane , Pichler Georg P. , Resel Margit , Posch Florian , Lembeck Anna L. , Stöger Herbert , Szkandera Joanna , Pummer Karl , Bauernhofer Thomas , Hutterer Georg C. , Gerger Armin , Stotz Michael , Pichler Martin
Published: October 2018

Metastatic testicular germ cell tumors (TGCTs) are a potentially curable disease by administration of risk-adapted cytotoxic chemotherapy. Nevertheless, a disease-relapse after curative chemotherapy needs more intensive salvage chemotherapy and significantly worsens the prognosis of TGCT patients. Circulating tumor markers (β-subunit of human chorionic gonadotropin (β-HCG), alpha-Fetoprotein (AFP), and Lactate Dehydrogenase (LDH)) are frequently used for monitoring disease recurrence in TGCT patients, though they lack diagnostic sensitivity and specificity. Increasing evidence suggests that serum levels of stem cell-associated microRNAs (miR-371a-3p and miR-302/367 cluster) are outperforming the traditional tumor markers in terms of sensitivity to detect newly diagnosed TGCT patients. The aim of this study was to investigate whether these miRNAs are also informative in detection of disease recurrence in TGCT patients after curative first line therapy. For this purpose, we measured the serum levels of miR-371a-3p and miR-367 in 52 samples of ten TGCT patients at different time points during disease relapse and during salvage chemotherapy. In our study, miR-371a-3p levels in serum samples with proven disease recurrence were 13.65 fold higher than levels from the same patients without evidence of disease (p = 0.014). In contrast, miR-367 levels were not different in these patient groups (p = 0.985). In conclusion, miR-371a-3p is a sensitive and potentially novel biomarker for detecting disease relapse in TGCT patients. This promising biomarker should be investigated in further large prospective trials.
Relationship between Serum BDNF Levels and Depressive Mood in Subacute Stroke Patients: A Preliminary Study
Authors: Chang Won Hyuk , Shin Min A , Lee Ahee , Kim Heegoo , Kim Yun-Hee
Published: October 2018

The aim of this preliminary study was to investigate the potential of serum brain-derived neurotrophic factor (BDNF) as a biomarker in poststroke depressive mood in subacute stroke patients. Thirty-eight subacute stroke patients were recruited in this study. All participants underwent the standard rehabilitation program that included 2 h of physical therapy daily and 1 h of occupational therapy five days a week. The rehabilitation period lasted two weeks during the subacute stroke phase. We measured the serum BDNF, proBDNF, and matrix metalloproteinase-9 before and one and two weeks after the standard rehabilitation program. In addition, all participants were assessed using the Geriatric Depression Scale-Short Form (GDS-SF) for depressive mood at three time points. Pearson correlation analysis was performed to determine the relationship between serum BDNF levels and the GDS-SF. The GDS-SF showed significant improvement during the standard rehabilitation program period (p < 0.05). The GDS-SF was significantly correlated with serum BDNF levels at each time point (p < 0.05). These results suggest that serum BDNF may be used as a biomarker for depressive mood in subacute stroke patients. However, further studies with larger study populations are needed to clarify these results.
Transcriptome Profiling Reveals Transcriptional Regulation by DNA Methyltransferase Inhibitor 5-Aza-2′-Deoxycytidine Enhancing Red Pigmentation in Bagged “Granny Smith” Apples (Malus domestica)
Authors: Ma Changqing , Liang Bowen , Chang Bo , Liu Li , Yan Jiuying , Yang Yazhou , Zhao Zhengyang
Published: October 2018

The red color of apples (Malus domestica) is an attractive trait for consumers. The green skinned “Granny Smith” cultivar develops red pigmentation after bagging treatment. DNA methylation plays an important role in various developmental processes in plants. To explore the possible functions of DNA methylation in the pigmentation of bagged “Granny Smith” apples, we first analyzed the anthocyanin content of fruit skin following treatment with the DNA methyltransferase inhibitor 5-aza-2′-deoxycytidine (5-aza-dC). The results revealed an increase in anthocyanin content in bagged fruits following 5-aza-dC treatment, while no anthocyanins were detected in unbagged fruits. In addition, 8482 differentially expressed genes between 5-aza-dC-treated and control groups were identified in bagged fruits by RNA sequencing, including genes encoding transcription factors, enzymes related to anthocyanin accumulation, and methylases. Changes in the expression of these genes may be responsible for 5-aza-dC-induced red pigmentation in bagged fruits of “Granny Smith”. The findings provide novel evidence for the involvement of DNA methylation in the red pigmentation of non-red-skinned apples.
Ghrelin Restores the Disruption of the Circadian Clock in Steatotic Liver
Authors: Wang Qin , Yin Yue , Zhang Weizhen
Published: October 2018

Obese mice demonstrate disruption of the circadian clock and feeding cycle. Circulating ghrelin, a hormone secreted mainly by gastric X/Alike cells, is significantly reduced in obese humans and animals. Here, we examined whether ghrelin improves the disruption of the circadian rhythm in steatotic hepatocytes and liver. The effects of ghrelin on hepatic circadian clock genes were studied in steatotic hepatocytes and liver of mice fed a high-fat diet (HFD) for 12 weeks. The circadian clock of cultured hepatocytes was synchronized by treatment with 100 nM dexamethasone for 1 h. Ghrelin was administrated to the cultured hepatocytes (10−8 M) or to mice at a dose of 11 nmol/kg/d for two weeks via a subcutaneous minipump. The mRNA and protein levels of core clock genes were analyzed. Steatosis significantly blunted the circadian pattern of clock genes such as Bmal1, Clock, and Per in cultured hepatocytes and liver. Treatment with ghrelin markedly restored the daily rhythm of the clock genes, with a robust oscillation between peak and trough in cultured hepatocytes isolated from obese mice. It also increased the abundance and expression amplitude of clock genes in steatotic liver, causing the peak of Clock to shift to the dark period and the peak of Per2 to shift to the light period compared with the control groups. Deletion of GHSR1a further deteriorated the derangement of clock gene patterns in obese mice. Ghrelin significantly increased the oscillations of mTOR/S6 signaling. We demonstrate that ghrelin restored the derangement of the circadian rhythm in steatotic liver via mTOR signaling.
MicroRNAs in Autoimmunity and Hematological Malignancies
Authors: Marco Mirco Di , Ramassone Alice , Pagotto Sara , Anastasiadou Eleni , Veronese Angelo , Visone Rosa
Published: October 2018

Autoimmunity and hematological malignancies are often concomitant in patients. A causal bidirectional relationship exists between them. Loss of immunological tolerance with inappropriate activation of the immune system, likely due to environmental and genetic factors, can represent a breeding ground for the appearance of cancer cells and, on the other hand, blood cancers are characterized by imbalanced immune cell subsets that could support the development of the autoimmune clone. Considerable effort has been made for understanding the proteins that have a relevant role in both processes; however, literature advances demonstrate that microRNAs (miRNAs) surface as the epigenetic regulators of those proteins and control networks linked to both autoimmunity and hematological malignancies. Here we review the most up-to-date findings regarding the miRNA-based molecular mechanisms that underpin autoimmunity and hematological malignancies.
A High-Density EST-SSR-Based Genetic Map and QTL Analysis of Dwarf Trait in Cucurbita pepo L.
Authors: Xiang Chenggang , Duan Ying , Li Hongbo , Ma Wei , Huang Sanwen , Sui Xiaolei , Zhang Zhonghua , Wang Changlin
Published: October 2018

As one of the earliest domesticated species, Cucurbita pepo (including squash and pumpkin) is rich in phenotypic polymorphism and has huge economic value. In this research, using 1660 expressed sequence tags-simple sequence repeats (EST-SSRs) and 632 genomic simple sequence repeats (gSSRs), we constructed the highest-density EST-SSR-based genetic map in Cucurbita genus, which spanned 2199.1 cM in total and harbored 623 loci distributed in 20 linkage groups. Using this map as a bridge, the two previous gSSR maps were integrated by common gSSRs and the corresponding relationships around chromosomes in three sets of genomes were also collated. Meanwhile, one large segmental inversion that existed between our map and the C. pepo genome was detected. Furthermore, three Quantitative Trait Loci (QTLs) of the dwarf trait (gibberellin-sensitive dwarf type) in C. pepo were located, and the candidate region that covered the major QTL spanned 1.39 Mb, which harbored a predicted gibberellin 2-β-oxidase gene. Considering the rich phenotypic polymorphism, the important economic value in the Cucurbita genus species and several advantages of the SSR marker were identified; thus, this high-density EST-SSR-based genetic map will be useful in Pumpkin and Squash breeding work in the future.
Histone Hyperacetylation as a Response to Global Brain Ischemia Associated with Hyperhomocysteinemia in Rats
Authors: Tóthová Barbara , Kovalská Mária , Kalenská Dagmar , Tomašcová Anna , Lehotský Ján
Published: October 2018

Epigenetic regulations play an important role in both normal and pathological conditions of an organism, and are influenced by various exogenous and endogenous factors. Hyperhomocysteinemia (hHcy), as a risk factor for several pathological conditions affecting the central nervous system, is supposed to alter the epigenetic signature of the given tissue, which therefore worsens the subsequent damage. To investigate the effect of hHcy in combination with ischemia-reperfusion injury (IRI) and histone acetylation, we used the hHcy animal model of global forebrain ischemia in rats. Cresyl violet staining showed massive neural disintegration in the M1 (primary motor cortex) region as well as in the CA1 (cornu ammonis 1) area of the hippocampus induced by IRI. Neural loss was significantly higher in the group with induced hHcy. Moreover, immunohistochemistry and Western blot analysis of the brain cortex showed prominent changes in the acetylation of histones H3 and H4, at lysine 9 and 12, respectively, as a result of IRI and induced hHcy. It seems that the differences in histone acetylation patterns in the cortical region have a preferred role in pathological processes induced by IRI associated with hHcy and could be considered in therapeutic strategies.
What Smart Campuses Can Teach Us about Smart Cities: User Experiences and Open Data
Authors: Vasileva Roza , Rodrigues Lucelia , Hughes Nancy , Greenhalgh Chris , Goulden Murray , Tennison Jeni
Published: October 2018

Universities, like cities, have embraced novel technologies and data-based solutions to improve their campuses with ‘smart’ becoming a welcomed concept. Campuses in many ways are small-scale cities. They increasingly seek to address similar challenges and to deliver improved experiences to their users. How can data be used in making this vision a reality? What can we learn from smart campuses that can be scaled up to smart cities? A short research study was conducted over a three-month period at a public university in the United Kingdom, employing stakeholder interviews and user surveys, which aimed to gain insight into these questions. Based on the study, the authors suggest that making data publicly available could bring many benefits to different groups of stakeholders and campus users. These benefits come with risks and challenges, such as data privacy and protection and infrastructure hurdles. However, if these challenges can be overcome, then open data could contribute significantly to improving campuses and user experiences, and potentially set an example for smart cities.
Food Reward and Distance Influence the Foraging Pattern of Stingless Bee, Heterotrigona itama
Authors: Basari Norasmah , Ramli Sarah Najiah , Mohd Khairi Nur 'Aina Syakirah
Published: October 2018

Beekeeping with stingless bee provides new opportunities to improve the incomes of many households in Malaysia through the sale of honey and other bee products. While Heterotrigona itama is one of the most commonly cultured species of stingless bees, its behavior is not very well understood. Hence, we conducted this study to investigate the behavior of H. itama in exploiting food sources by ascertaining the nectar sugar concentration preferred by the bee. We also aimed to determine the preferred distance of food source from the beehive. Our results suggest that H. itama prefers high sugar concentrations of 35% and above, and most of the bees preferred to forage close to their hive to collect food. We discuss how nectar concentration, food distance, and abiotic factors influence the number of bees exploiting food sources and the overall foraging pattern of H. itama.
Multivariate Statistical Approach to Image Quality Tasks
Authors: Gupta Praful , Bampis Christos , Glover Jack , Paulter Nicholas , Bovik Alan
Published: October 2018

Many existing natural scene statistics-based no reference image quality assessment (NR IQA) algorithms employ univariate parametric distributions to capture the statistical inconsistencies of bandpass distorted image coefficients. Here, we propose a multivariate model of natural image coefficients expressed in the bandpass spatial domain that has the potential to capture higher order correlations that may be induced by the presence of distortions. We analyze how the parameters of the multivariate model are affected by different distortion types, and we show their ability to capture distortion-sensitive image quality information. We also demonstrate the violation of Gaussianity assumptions that occur when locally estimating the energies of distorted image coefficients. Thus, we propose a generalized Gaussian-based local contrast estimator as a way to implement non-linear local gain control, which facilitates the accurate modeling of both pristine and distorted images. We integrate the novel approach of generalized contrast normalization with multivariate modeling of bandpass image coefficients into a holistic NR IQA model, which we refer to as multivariate generalized contrast normalization (MVGCN). We demonstrate the improved performance of MVGCN on quality-relevant tasks on multiple imaging modalities, including visible light image quality prediction and task success prediction on distorted X-ray images.
Optimizing Surface Micro Grooving to Reduce the Checking and Cupping of Douglas Fir, Western Hemlock and White Spruce Decking Exposed to Natural Weathering
Authors: Heshmati Sina , Mazloomi Mohammad Sadegh , Evans Philip David
Published: October 2018

Machining grooves into the surface of pine and fir (Abies spp.) deckboards reduces undesirable checking that develops when “profiled” boards are exposed to the weather. We aim to develop improved profiles for Douglas fir, western hemlock and white spruce decking to reduce their susceptibility to checking, and understand how profile geometry influences the stresses that cause checking. We varied the width and depth of grooves in profiled deckboards, exposed deckboards to the weather, and measured checking and cupping of boards. A numerical model examined the effect of groove depth on the moisture-induced stresses in profiled spruce boards. Profiling significantly reduced checking, but increased cupping of deckboards made from all three species. Western hemlock checked more than the other two species. Profiles with narrow grooves (rib profiles) were better at restricting checking than profiles with wider grooves. A rib profile with deeper grooves developed smaller stresses than a rib profile with shallower grooves, and boards with the former profile checked less than boards with shallower grooves. We conclude that checking of profiled Douglas fir, western hemlock and white spruce decking is significantly reduced by changing profile geometry, and our results suggest the best profiles to reduce checking of all three species.
Tidal Datums with Spatially Varying Uncertainty in North-East Gulf of Mexico for VDatum Application
Authors: Tang Liujuan , Myers Edward , Shi Lei , Hess Kurt , Carisio Alison , Michalski Michael , White Stephen , Hoang Cuong
Published: October 2018

We conducted a VDatum-spatially varying uncertainty study for the North-East Gulf of Mexico. The newly developed tide model incorporated the latest available National Ocean Service (NOS) bathymetry survey data and National Geodetic Survey (NGS) shoreline data, and the datum products reflected the updated tidal datum data from the Center for Operational Oceanographic Products and Services (CO-OPS). A gridding technique based on the wavelength of long waves in the deep ocean was applied to improve model efficiency. In this study, we highlight the creation of the tidal datum products and associated spatially varying uncertainty, which was developed by blending the model results, observations, and measurement errors together using a spatially varying uncertainty method based on a variational approach. The study found that model errors, measurement errors, and lack of observations can contribute to large uncertainty in the tidal datum products. The need for high quality bathymetry data in coastal areas is essential for reducing model error. As for the large uncertainty due to lack of observations or large measurement error, this can be improved by placement of new observations with high precision. Compared to a single uncertainty value, the spatially varying uncertainty provides more accurate representation of the uncertainty for the tidal datum products in VDatum. The uncertainty results will be used to help with decision-making on placement of new tide gauges to further reduce the uncertainty in the VDatum products.
Main Development Problems of Vulnerability Mapping of Sea-Coastal Zones to Oil Spills
Authors: Shavykin Anatoly , Karnatov Andrey
Published: October 2018

Vulnerability mapping of sea-coastal zones is an important element of oil spill response plans, environmental support for offshore projects, and the integrated management of the marine environment. The creation of such maps is a complex scientific problem. In their development, it is necessary to take into account differences in the nature of biotic and abiotic components existing in the cartographic area, dissimilarities in their relative vulnerability and significance, the seasonal variability of ecosystem components, and other factors. The purpose of this paper is to briefly review the main elements of international and Russian methods of mapping the vulnerability of sea-coastal zones to oil spills, and the development problems of such maps, including problems of using rank (ordinal) values, and to note possible solutions. Based on the analysis of key existing international and Russian approaches to vulnerability mapping, it was concluded that almost all methods of map calculations use rank (ordinal) values. However, arithmetic operations cannot be performed with them, as they lead to incorrect results. The paper shortly describes the main problems of mapping the vulnerability of sea-coastal zones to oil (the choice of the map scales and season limits for them, differences in the units of biota abundance, the calculation of relative vulnerability coefficients for the considered biotic components, the summation of the vulnerability of objects of different types, etc.). For some problems, possible solutions are outlined.
Baroclinic Effect on Modeling Deep Flow in Brown Passage, BC, Canada
Authors: Lin Yuehua , Fissel David B. , Mudge Todd , Borg Keath
Published: October 2018

Brown Passage is a deep (up to 200 m) ocean channel connecting the western offshore waters of Hecate Strait and Dixon Entrance on the Pacific continental shelf with the eastern inland waters of Chatham Sound in Northern British Columbia, Canada. A high-resolution 3D finite difference hydrodynamic model, COastal CIRculation and SEDiment transport Model (COCIRM-SED), was developed in 2010 and 2013 to determine the tidal and wind-driven currents of this area. The barotropic model results for ocean currents were found to be in reasonably good agreement with the historical ocean current observations at near-surface and middle depth available for Brown Passage. Operated from October 2014 to April 2015, the first modern oceanographic measurement program in Brown Passage found surprisingly strong near-bottom currents (the 99th percentile current speed reaches 53 cm/s at 196 m). As a result, the COCIRM-SED model was modified and rerun, with the most important change incorporating water density/salinity fields as modeled variables. This change led to considerable improvements in the ability of the model to generate episodes of relatively strong currents in the bottom layers. The bottom intensification in ocean currents in Brown Passage is shown to be due to semi-diurnal internal tides, which were not previously included in the barotropic version of the 3D model. This finding for the near-bottom flow from the qualitative modeling study is important for applications of the potential sediment deposition and resuspension studies.
Market Reactions to Supply Chain Management Excellence
Authors: Shi Min , Yu Wei
Published: October 2018

A highly-respected public recognition of supply chain management (SCM) excellence is the Supply Chain Top 25 List, published annually by AMR Research. By employing event study method, this study extensively examined stock market reactions to annual announcements of the AMR Supply Chain Top 25 List, under various market scenarios. The results showed that SCM leading firms consistently outperform market portfolios around annual press-release dates. The mean abnormal returns observed in the event window (0, +1) were positive and statistically significant. In addition, the findings were robust across different estimation models and various market indexes adopted in the event study. At the same time, it is worth noting that the event effect on market performance was temporary and diminished within 5 trading days. This study makes contributions to the growing body of knowledge on the strategic values of firm reputation in general, and for SCM excellence in particular.
Combined Use of Optical and Synthetic Aperture Radar Data for REDD+ Applications in Malawi
Authors: Hirschmugl Manuela , Sobe Carina , Deutscher Janik , Schardt Mathias
Published: October 2018

Recent developments in satellite data availability allow tropical forest monitoring to expand in two ways: (1) dense time series foster the development of new methods for mapping and monitoring dry tropical forests and (2) the combination of optical data and synthetic aperture radar (SAR) data reduces the problems resulting from frequent cloud cover and yields additional information. This paper covers both issues by analyzing the possibilities of using optical (Sentinel-2) and SAR (Sentinel-1) time series data for forest and land cover mapping for REDD+ (Reducing Emissions from Deforestation and Forest Degradation) applications in Malawi. The challenge is to combine these different data sources in order to make optimal use of their complementary information content. We compare the results of using different input data sets as well as of two methods for data combination. Results show that time-series of optical data lead to better results than mono-temporal optical data (+8% overall accuracy for forest mapping). Combination of optical and SAR data leads to further improvements: +5% in overall accuracy for land cover and +1.5% for forest mapping. With respect to the tested combination methods, the data-based combination performs slightly better (+1% overall accuracy) than the result-based Bayesian combination.
Assessing Local Indigenous Knowledge and Information Sources on Biodiversity, Conservation and Protected Area Management at Khuvsgol Lake National Park, Mongolia
Authors: McCarthy Christopher , Shinjo Hitoshi , Hoshino Buho , Enkhjargal Erdenebuyan
Published: October 2018

Indigenous knowledge about biodiversity and conservation is valuable and can be used to sustainably manage protected areas; however, indigenous communities continue to be marginalized due to the belief that their values and behaviors do not align with the overarching mission of conservation. This paper explores the extent of local knowledge and awareness of biodiversity, conservation and protected area management of indigenous communities at Khuvsgol Lake National Park, Mongolia. We investigate current levels of biodiversity awareness and explore perceptions toward conservation values and park management governance. Most respondents had a high awareness of existing biodiversity and held positive attitudes toward nature conservation and protected areas; however, insufficient knowledge of park rules and low levels of trust between local residents and park authorities may undermine conservation objectives in the long run. We identify an unequal share of economic benefits from tourism and preferential treatment toward elite business owners as a source of conflict. Limited information channels and poor communication between local residents and park authorities are also a source for low-level participation in conservation activities. Leveraging the increasing use of information communication technology, such as mobile phones, can serve as a new mechanism for improved information sharing and transparent reporting between local communities, conservationists and protected area authorities.
Stable GaSe-Like Phosphorus Carbide Monolayer with Tunable Electronic and Optical Properties from Ab Initio Calculations
Authors: Cai Xiaolin , Zhu Zhili , Yu Weiyang , Niu Chunyao , Wang Jianjun , Wang Baoji , Li Xiaohua , Zhang Liwei , Zhao Ruiqi , Jia Yu
Published: October 2018

On the basis of density functional theory (DFT) calculations, we propose a stable two-dimensional (2D) monolayer phosphorus carbide (PC) with a GaSe-like structure, which has intriguing electronic and optical properties. Our calculated results show that this 2D monolayer structure is more stable than the other allotropes predicted by Tománek et al. [Nano Lett., 2016, 16, 3247–3252]. More importantly, this structure exhibits superb optical absorption, which can be mainly attributed to its direct band gap of 2.65 eV. The band edge alignments indicate that the 2D PC monolayer structure can be a promising candidate for photocatalytic water splitting. Furthermore, we found that strain is an effective method used to tune the electronic structures varying from direct to indirect band-gap semiconductor or even to metal. In addition, the introduction of one carbon vacancy in such a 2D PC structure can induce a magnetic moment of 1.22 µB. Our findings add a new member to the 2D material family and provide a promising candidate for optoelectronic devices in the future.
Strengthening Effects of Zn Addition on an Ultrahigh Ductility Mg-Gd-Zr Magnesium Alloy
Authors: Hu Yaobo , Zhang Chao , Zheng Tianxu , Pan Fusheng , Tang Aitao
Published: October 2018

A newly developed Mg-2Gd-0.5Zr-xZn (x = 0.5, 1.0, 2.0, 3.0 wt %) alloy system exhibits significant strengthening by doping with Zn. In order to understand the strengthening mechanism, the microstructure, texture evolution, and mechanical properties of ultrahigh ductility Mg-2Gd-0.5Zr alloys with a Zn addition were systematically investigated. The addition of Zn results in the formation of Mg-Gd-Zn intermetallic compounds along grain boundaries, which encourages grain refinement during hot extrusion via the particle stimulated nucleation (PSN) mechanism. Furthermore, during texture sharpening the pole changes from <20 2 ¯ 1> to <01 1 ¯ 0>, which also occurred in the extruded alloys with Zn addition, which is unfavorable for the basal slip and tensile twinning. Mg-2Gd-0.5Zr-3Zn shows well-balanced strength and ductility with a tensile yield strength (YS) and ultimate tensile strength (UTS) of 285 and 314 MPa, accompanied by a high tensile elongation of 24%. They are superior to those of commercial AZ31. The enhanced strength is attributed to grain refinement, precipitation strengthening, and texture sharpening induced by alloying with Zn. The research result is also of great value to the development of low rare-earth, high strength, and high room temperature ductility magnesium alloy.
A Rational Design of the Sintering-Resistant Au-CeO2 Nanoparticles Catalysts for CO Oxidation: The Influence of H2 Pretreatments
Authors: Sun Yuqi , Liu Wei , Tian Miao , Wang Liguo , Wang Zhongpeng
Published: October 2018

The redox pretreatment of samples is one of the crucial ways of altering the catalytic properties of the supported noble metal materials in many heterogeneous reactions. Here, H2-reducing pretreatment is reported to enhance the thermal stability of Au-CeO2 catalysts prepared by the deposition–precipitation method and calcination at 600 °C for CO oxidation. In order to understand the improved activity and thermal stability, a series of techniques were used to characterize the physico-chemical changes of the catalyst samples. H2 pretreatment may lead to: (i) a strong metal–support interaction (SMSI) between Au nanoparticles (NPs) and CeO2, evidenced by the particular coverage of Au NPs by CeO2, electronic interactions and CO adsorption changes. (ii) the production of surface bicarbonates which can accelerate CO oxidation. As a result, the H2 pretreatment makes the Au NPs more resistant to sintering at high temperature and enhances the CO oxidation activity. Furthermore, this reduction pretreatment strategy may provide a potential approach to enhance the thermal-stability of other supported noble metal catalysts.
Recent Progress in Magnetron Sputtering Technology Used on Fabrics
Authors: Tan Xue-Qiang , Liu Jian-Yong , Niu Jia-Rong , Liu Jia-Yin , Tian Jun-Ying
Published: October 2018

The applications of magnetron sputtering technology on the surface coating of fabrics have attracted more and more attention from researchers. Over the past 15 years, researches on magnetron sputtering coated fabrics have been mainly focused on electromagnetic shielding, bacterial resistance, hydrophilic and hydrophobic properties and structural color etc. In this review, recent progress of the technology is discussed in detail, and the common target materials, technologies and functions and characterization of coated fabrics are summarized and analyzed. Finally, the existing problems and future prospects of this developing field are briefly proposed and discussed.
Improving Pallet Mover Safety in the Manufacturing Industry: A Bow-Tie Analysis of Accident Scenarios
Authors: Van Nunen Karolien , Swuste Paul , Reniers Genserik , Paltrinieri Nicola , Aneziris Olga , Ponnet Koen
Published: October 2018

A Belgian manufacturing company uses pallet movers for internal transport. Despite the company’s efforts to improve occupational safety, accidents with pallet movers remain noteworthy. In order to control occupational accidents, it is crucial to have a clear view of the potential accident scenarios that are present in a company. The bow-tie method is a way to capture and visualize these accident processes in an integrative way. Included in the bow-tie are safety barriers (both technical as organizational and human) and management delivery systems that can intervene in these accident processes. Once bow-ties are composed, they are an excellent point of departure to assign indicators to the safety barriers and management delivery systems in order to control (i.e., prevent or mitigate) accident scenarios. Two types of indicators can be distinguished. Firstly, there are general indicators that are assigned to management delivery systems interrupting multiple accident scenarios, which can yield a higher safety gain (as they intervene in multiple accident scenarios). Secondly, there are scenario-specific indicators targeting one specific accident scenario, which can be valuable as they target a specific problem in the company. For the development of the bow-ties, a multi-method design with the inclusion of different data sources was used, leading to a comprehensive overview. This makes the bow-tie analysis of internal transport with pallet movers transferable to other settings where pallet movers are used for internal transport.
Biofabrication of Electrospun Scaffolds for the Regeneration of Tendons and Ligaments
Authors: Sensini Alberto , Cristofolini Luca
Published: October 2018

Tendon and ligament tissue regeneration and replacement are complex since scaffolds need to guarantee an adequate hierarchical structured morphology, and non-linear mechanical properties. Moreover, to guide the cells’ proliferation and tissue re-growth, scaffolds must provide a fibrous texture mimicking the typical of the arrangement of the collagen in the extracellular matrix of these tissues. Among the different techniques to produce scaffolds, electrospinning is one of the most promising, thanks to its ability to produce fibers of nanometric size. This manuscript aims to provide an overview to researchers approaching the field of repair and regeneration of tendons and ligaments. To clarify the general requirements of electrospun scaffolds, the first part of this manuscript presents a general overview concerning tendons’ and ligaments’ structure and mechanical properties. The different types of polymers, blends and particles most frequently used for tendon and ligament tissue engineering are summarized. Furthermore, the focus of the review is on describing the different possible electrospinning setups and processes to obtain different nanofibrous structures, such as mats, bundles, yarns and more complex hierarchical assemblies. Finally, an overview concerning how these technologies are exploited to produce electrospun scaffolds for tendon and ligament tissue applications is reported together with the main findings and outcomes.
Rheological Behavior of Rockmass Supported with Rockbolts Based on Viscoelastic Analysis Method
Authors: Wang Gang , Han Wei , Liu Chuanzheng , Wang Ke , Luan Hengjie
Published: October 2018

In this paper, we present the viscoelastic solutions for rockmass supported with discretely mechanically or frictionally coupled (DMFC) rockbolts to reveal the coupling rheological mechanisms. The analytical solutions are first acquired by applying the Laplace inverse transforms. The effect of different viscosity coefficients and supporting parameters on the coupling model rheological behavior are then investigated. It is concluded that the variation of the rockbolt axial force or rock mass stress and displacement have a close relationship with rheological parameters and support parameters. In addition, the variations of mechanical states of rockbolts and rock mass are closely related to the rheological model.
Synthesis of Novel Chitin Derivatives Bearing Amino Groups and Evaluation of Their Antifungal Activity
Authors: Zhang Jingjing , Luan Fang , Li Qing , Gu Guodong , Dong Fang , Guo Zhanyong
Published: October 2018

Chemical modification is one of the most effective methods to improve the biological activity of chitin. In the current study, we modified C3-OH and C6-OH of chitin (CT) and successfully synthesized 6-amino-chitin (NCT) and 3,6-diamino-chitin (DNCT) through a series of chemical reactions. The structure of NCT and DNCT were characterized by elemental analyses, FT-IR, 13C NMR, XRD, and SEM. The inhibitory effects of CT, NCT, and DNCT against six kinds of phytopathogen (F. oxysporum f. sp. cucumerium, B. cinerea, C. lagenarium, P. asparagi, F. oxysporum f. niveum, and G. zeae) were evaluated using disk diffusion method in vitro. Meanwhile, carbendazim and amphotericin B were used as positive controls. Results revealed that 6-amino-chitin (NCT) and 3,6-diamino-chitin (DNCT) showed improved antifungal properties compared with pristine chitin. Moreover, DNCT exhibited the better antifungal property than NCT. Especially, while the inhibition zone diameters of NCT are ranged from 11.2 to 16.3 mm, DNCT are about 11.4–20.4 mm. These data demonstrated that the introduction of amino group into chitin derivatives could be key to increasing the antifungal activity of such compounds, and the greater the number of amino groups in the chitin derivatives, the better their antifungal activity was.