bluuebunny/crossref_metadata_2025 huggingface dataset:
Nature of Interactions between Boron Clusters: Extended Delocalization and Retention of Aromaticity post Oxidation
Authors: DAR SOHAIL HAMID , Pancharatna Pattath D. , Balakrishnarajan Musiri M.
Published: March 2023

Polyhedral boron clusters are lauded as 3D-aromatic that frequently form interconnected periodic networks in boron-rich borides with metal and non-metals having high thermodynamic stability and hardness. This leads to the question of whether the spherical delocalization of electrons in these clusters is extended across the network as in organic aromatic networks. These borides also frequently show partial oxidation, having fewer electrons than that is mandated by electron counting rules, whose impact on their aromatic stability and geometry remains mysterious. Understanding the nature of electronic communication between polyhedra in polyhedral borides is largely unknown though it is crucial for the rational design of advanced materials with desirable mechanical, electronic and optical properties. Here we show that electronic delocalization across polyhedral clusters has a significant impact on their structure and stability. Our computational inquiry on closo borane dimers shows substantial variation in conjugation with the ideal electron count. Upon two-electron oxidation, instead of forming exohedral multiple bonding that disrupts the aromaticity, it undergoes subtle geometric transformations that conserve aromaticity. The nature of geometric transformation depends on the HOMO that is decided locally on the polyhedral degree of the interacting vertices. The prevalence of π-type interactions as HOMO in tetravalent vertices encourage conjugation across clusters and turn into a macropolyhedral system hosting a rhombic linkage between clusters upon oxidation. In contrast, the σ-type interactions dominate the HOMO of pentavalent vertices that prefers to confine aromaticity within the polyhedra by separating them with localized 3c-2e bonds. Our findings expose the fundamental bonding principles that govern the interaction between boron clusters and will provide chemical guidance for the design and analysis of polyhedral boride networks with desired properties.
Cytoplasmic accumulation and permeability of antibiotics in Gram positive and Gram negative bacteria visualized in real-time via a fluorogenic tagging strategy
Authors: Squire Scott , Sebghati Sepehr , Hammond Ming
Published: March 2023

In this study, we describe a real-time live cell assay for compound accumulation and permeability in both Gram positive and Gram negative bacteria. The assay utilizes a novel fluorogenic tagging strategy that permits direct visualization of compound accumulation dynamics in the cytoplasm of live cells, unobscured by washing or other processing steps. Quantitative differences could be reproducibly measured by flow cytometry at compound concentrations below the limit of detection for MS-based approaches. We establish the fluorogenic assay in E. coli and B. subtilis and compare the intracellular accumulation of two antibiotics, ciprofloxacin and ampicillin, with related pharmacophores in these model Gram negative and Gram positive bacteria.
Matrix of Orthogonalized Atomic Orbital Coefficients Representation for Radicals and Ions
Authors: Llenga Stiv , Gryn'ova Ganna
Published: March 2023

Chemical (molecular, quantum) machine learning relies on representing molecules in unique and informative ways. Here, we present matrix of orthogonalized atomic orbital coefficients (MAOC) as a quantum-inspired molecular and atomic representation containing both structural (composition and geometry) and electronic (charge and spin multiplicity) information. MAOC is based on a cost-effective localization scheme that represents localized orbitals via a predefined set of atomic orbitals. The latter can be constructed from such small atom-centered basis sets as pcseg-0 and STO-3G in conjunction with guess (non-optimized) electronic configuration of the molecule. Importantly, MAOC is suitable for representing monatomic, molecular, and periodic systems, and can distinguish compounds with identical compositions and geometries but distinct charges and spin multiplicities. Using principal component analysis, we constructed a more compact but equally powerful version of MAOC – PCX-MAOC. To test the performance of full and reduced MAOC and several other representations (CM, SOAP, SLATM, and SPAHM), we used a kernel ridge regression machine learning model to predict frontier molecular orbital energy levels and ground state single-point energies for chemically diverse neutral and charged, closed- and open-shell molecules from an extended QM7b dataset, as well as two new datasets, N-HPC-1 (N-heteropolycycles) and REDOX (nitroxyl and phenoxyl radicals, carbonyl and cyano compounds). MAOC affords accuracy that is either similar or superior to other representations for a range of chemical properties and systems.
Photophysical Study on the Effect of the External Potential on NiO-Based Photocathodes
Authors: Zhu Kaijian , Einhaus Lisanne , Mul Guido , Huijser Annemarie
Published: March 2023

In present study we investigate the effect of the external potential on a dye-sensitized NiO photocathode on the light-induced charge carrier dynamics by time-resolved photoluminescence and femtosecond transient absorption spectroscopy under operating conditions. Instead of the anticipated acceleration of photoinduced hole injection from dye into NiO at more negative applied potential, we observe that both hole injection and charge recombination are slowed down. We assign this effect to a variation in OH- ion concentration in the inner Helmholtz plane (IHP) of the electrochemical double layer with applied potential, showing that ion adsorption and desorption onto the NiO surface play an essential role as a relay in light-induced charge transfer and recombination. Our work highlights the key role of ions at the electrode surface and in the electrolyte in the realization of efficient solar to fuel devices.
Modulating Enzyme’s Activity and Specificity through Pre-Installed Posttranslational Modifications (PTMs) on Substrate: The Role of PTM-induced Substrate-Assisted Stimulation
Authors: Guo Hong , Qian Ping
Published: March 2023

Understanding the underlying principles for crosstalk involving posttranslational modifications (PTMs) is of fundamental importance. In this article, we review some of previous results which indicated that pre-installed PTMs on nucleosome substrates (or nucleosome peptides) may stimulate the activity and change the specificity of histone modifying enzymes for the next PTMs. Discussions are also made on the results showing that ubiquitin (Ub) within the M1-diUb substrate could remodel the active site of OTULIN, a human deubiquitinase (DUB), and stimulate its activity. We term such stimulation effects as PTM-induced substrate-assisted stimulation (PTM-induced SAS) and propose that it could be one of the general strategies in PTM crosstalk and may provide a unique way to relay signals. It is suggested that although PTM-induced SAS seems to offer an attractive mechanism, detailed studies are still necessary to fully understand how the stimulations are created and translated into the increased activities and how widely it may occur in biological systems.
Understanding Formation of the InPd3 Polymorphs: A DFT Study
Authors: ROY NILANJAN
Published: March 2023

The intriguing experimental results regarding the synthesis and structure types adopted by binary InPd3 have been fundamentally addressed using first-principles density functional theory calculations. Longer annealing time at higher temperature leads to stronger and more optimized heteroatomic In-Pd contacts that result in the extended ordering between them and leading to the ZrAl3-structure type; followed by another ordered derivative TiAl3-type and the metastable disordered AuCu-type when the annealing time and temperature were reduced. The thermodynamic stability order of these three polymorphs of InPd3; i.e. ZrAl3-type > TiAl3-type > AuCu-type is understood from the correlation between formation enthalpies, Madelung energies, and electronic structure, chemical bonding analysis.
G-quadruplex Hydrogel-based Stimuli-responsive High-internal-phase Emulsion Scaffold for Biocatalytic Cascades and Synergistic Antimicrobial Activity
Authors: Das Sourav , Solra Manju , Sahoo Jagabandhu , Srivastava Abhay , S Fathima , De Mrinmoy , Rana Subinoy
Published: March 2023

High internal phase emulsions (HIPEs) are non-equilibrium systems with distorted liquid droplet shapes consisting of high volume of internal phase (>74% v/v), enabling high loading of pharmaceutics and useful viscoelastic properties. Stability of the HIPEs is low and requires a high volume of surfactants in the continuous phase, which is environmentally unfriendly. Utilization of hydrogel as the continuous phase to stabilize HIPEs would offer a robust method to produce stable HIPE gels displaying reconfigurable and biocompatible properties, as well as access the huge repertoire of different biocompatible hydrogels. Herein, we introduce a new gel-immobilized HIPE (HIPEG) using chiral G-quadruplex (GQ) based hydrogel with external stimuli-responsive dual-drug release behavior, which is scarce for HIPEs. The hydrophilic and hydrophobic compartments of HIPEGs allow encapsulation of different drugs in both the compartments, with stimuli-responsive diffusion mediated release. Encapsulation of natural oils and antibiotics produces synergistic antimicrobial effects on both Gram positive (MRSA) and Gram negative (P. aeruginosa) bacterial strains. Moreover, we demonstrate biocatalytic reaction networks utilizing compartmentalized enzyme dyads. Notably, the ideal viscoelastic property of HIPEGs enables 3D bioprinting into different shapes, making the scaffold potential for tissue engineering applications. Altogether, our approach offers a one-step route to stimuli-responsive HIPE microcompartments immobilized in GQ hydrogels with endogenous reactivity and high viscoelasticity, and provides a viable step towards the development of biocompatible soft materials with tailorable functionality.
Development of electrochemical cells for spatially resolved analysis using a multi-technique approach: from conventional experiments to X-ray nanoprobe beamlines
Authors: Vicente Rafael , Raju Swathi , Gomes Heloisa , Neckel Itamar , Tolentino Hélio , Sebastián Fernández Pablo
Published: March 2023

Real (electro-)catalysts are often heterogeneous, and their activity and selectivity depend on the properties of specific active sites. Therefore, unveiling the so-called structure-activity relationship is essential for a rational search for better materials and, consequently, for the development of the field of (electro-)catalysts. Thus, spatially resolved techniques are powerful tools as they allow us to characterize and/or measure the activity and selectivity of different regions of heterogeneous catalysts. To take full advantage of that, we have developed spectroelectrochemical cells (SEC) to perform spatially resolved analysis using X-ray nanoprobe synchrotron beamlines, and conventional pieces of equipment. Here, we describe the techniques available at the Carnaúba beamline at Sirius-LNLS storage ring, then we show how our SECs enable obtaining X-ray (XRF, XRD, XAS, etc.) and vibrational spectroscopy (FTIR and Raman) contrast images. Through some proof-of-concept experiments, we demonstrate how using a multi-technique approach could render a complete and detailed analysis of an (electro-)catalyst overall performance.
Selective Chemical Substitution in Intermetallic Compounds: DFT Study of Two Representative Cases: Cu5Zn3Sb2 and InPd2Cu
Authors: ROY NILANJAN , Kuila Sandip Kumar
Published: March 2023

The unique site substitution of Zn in the structure of tetragonal Cu3Zn2Sb2 and the substitution of Cu in the binary InPd3, followed by the formation of Cu5Zn3Sb2 and InPd2Cu has been addressed from fundamental perspectives. First principles total energy calculations, and semi-empirical electronic structure calculations using both the density of states, crystal orbital Hamilton population, and Mulliken population analysis were performed to understand the observed compositional range for both the titled cases and to address the “coloring problem” for the experimentally observed site preferences.
Structure-based design and characterization of Parkin-activating mutations
Authors: Stevens Michael U , Croteau Nathalie , Eldeeb Mohamed A , Antico Odetta , Zeng Zhi Wei , Toth Rachel , Durcan Thomas M , Springer Wolfdieter , Fon Edward A , Muqit Miratul MK , Trempe Jean-François
Published: March 2023

Autosomal recessive mutations in the Parkin gene cause Parkinson’s disease. Parkin encodes an ubiquitin E3 ligase that functions together with the kinase PINK1 in a mitochondrial quality control pathway. Parkin exists in an inactive conformation mediated by autoinhibitory domain interfaces. Thus, Parkin has become a target for the development of therapeutics that activate its ligase activity. Yet, the extent to which different regions of Parkin can be targeted for activation remained unknown. Here, we have used a rational structure-based approach to design new activating mutations in both human and rat Parkin across interdomain interfaces. Out of 31 mutations tested, we identified 11 activating mutations that all cluster near the RING0:RING2 or REP:RING1 interfaces. The activity of these mutants correlates with reduced thermal stability. Furthermore, three mutations V393D, A401D, and W403A rescue a Parkin S65A mutant, defective in mitophagy, in cell-based studies. Overall our data extend previous analysis of Parkin activation mutants and suggests that small molecules that would mimic RING0:RING2 or REP:RING1 destabilisation offer therapeutic potential for Parkinson’s disease patients harbouring select Parkin mutations.
MicroRNAs in tear fluids predict underlying molecular changes associated with Alzheimer’s disease
Authors: Wijesinghe Printha , Xi Jeanne , Cui Jing , Campbell Matthew , Pham Wellington , Matsubara Joanne A
Published: March 2023

Extracellular circulating microRNAs (miRNAs) have been discussed as potential biomarkers for Alzheimer’s disease (AD) diagnosis. As the retina is a part of the CNS, we hypothesize that miRNAs expression levels in the brain, particularly neocortex–hippocampus, eye tissues, and tear fluids are similar at different stages of AD progression. Ten miRNA candidates were systematically investigated in transgenic APP-PS1 mice, noncarrier siblings, and C57BL/6J wild-type controls at young and old ages. Relative expression levels of tested miRNAs revealed a similar pattern in both APP-PS1 mice and noncarrier siblings when compared with age- and sex-matched wild-type controls. However, the differences seen in expression levels between APP-PS1 mice and noncarrier siblings could possibly have resulted from underlying molecular etiology of AD. Importantly, miRNAs associated with amyloid beta (Aβ) production (-101a, -15a, and -342) and proinflammation (-125b, -146a, and -34a) showed significant up-regulations in the tear fluids with disease progression, as tracked by cortical Aβ load and reactive astrogliosis. Overall, for the first time, the translational potential of up-regulated tear fluid miRNAs associated with AD pathogenesis was comprehensively demonstrated.
Potency assessment of IFNγ-producing SARS-CoV-2-specific T cells from COVID-19 convalescent subjects
Authors: Gil-Bescós Rubén , Ostiz Ainhoa , Zalba Saioa , Tamayo Ibai , Bandrés Eva , Rojas-de-Miguel Elvira , Redondo Margarita , Zabalza Amaya , Ramírez Natalia
Published: March 2023

The development of new therapies for COVID-19 high-risk patients remains necessary to prevent additional deaths. Here, we studied the phenotypical and functional characteristics of IFN-γ producing-SARS-CoV-2-specific T cells (SC2-STs), obtained from 12 COVID-19 convalescent donors, to determine their potency as an off-the-shelf T cell therapy product. We found that these cells present mainly an effector memory phenotype, characterized by the basal expression of cytotoxicity and activation markers, including granzyme B, perforin, CD38, and PD-1. We demonstrated that SC2-STs could be expanded and isolated in vitro, and they exhibited peptide-specific cytolytic and proliferative responses after antigenic re-challenge. Collectively, these data demonstrate that SC2-STs can be a suitable candidate for the manufacture of a T cell therapy product aimed to treat severe COVID-19.
Complex Historical Research about Formation Health Care Systems in Eastern Siberia in the 1920th
Authors:   Irkutsk State University, Kazarin V. N.
Published: March 2023

The review of the monograph by V. A. Shalamov is submitted. An integrated approach of the author to research of problems of formation and evolution of a health care system, its staffing, activity of authorities and the public in fight against epidemics and social diseases, features of sanitary and hygienic work, adaptation of pharmaceutical service to real conditions of Eastern Siberia in the 1920th, participation in public health care of the region of the Russian society of the Red Cross is noted. The analysis of an historical basis of the monograph and to definition by the author of degree of study of a problem is given. The conclusion is drawn on a contribution of the reviewed monograph to studying the Soviet health care system and to a historiography of social policy of the state to one of the most difficult periods of history of the 20th century.
The First in Siberia: From the History of the Dissertation Council in Historical Sciences at ISU. Part 3: Review of Dissertations on Domestic History
Authors:   Irkutsk State University, Ivanov A. A. , Kuznetsov S. I. ,   Irkutsk State University, Petrushin Yu. A. ,   Irkutsk State Transport University
Published: March 2023

The authors consistently consider the main problems of qualification studies, highlighting from the total number of works performed on the history of tsarist exile, the repressions of the Soviet state, the history of the court, as well as dissertations on various aspects of World War II.
Assessment and Treatment of Childhood-Onset Conduct Disorder: A Literature Review
Authors: Szorady Bryanna N.
Published: March 2023

Introduction: Conduct disorder (CD) is among the most highly represented diagnostic issues in child psychiatry. Current research suggests that early-onset CD is predictive of a worse prognosis and trajectory than other CD subtypes if not subsequently met with appropriate psychological assessment and symptom management. This paper aims to provide an overview of the literature from 2014 to 2021 in assessment and intervention protocols that target childhood-onset type specific CD, and appraise associated barriers implicated by the findings.
Methods: This review involved a thorough literature search in electronic databases to extract empirical studies directly related to childhood-onset CD. The review was performed on PsycINFO and PubMed using the following search words: “conduct disorder(s)” OR “CD” OR “conduct disordered”, AND “child(hood)-onset” OR “elementary-onset” OR “early-onset”, AND “assessment” OR “evaluation” OR “examination”, AND “intervention” OR “treatment” OR “symptom management”.
Results: Based on trends, articles were sorted into three common topics: assessment, treatment, and barriers to psychological services. The studies demonstrated the importance of sensitive and specific assessment tools, neural measures, behavioural markers, and the limited prosocial emotions (LPE) specifier. The results indicated that comorbidities, tailored school- and family-based intervention, parent-child conflict, and the LPE specifier in addition to the age-of-onset subtype is an area of research for clinicians.
Discussion: Research has shown that childhood-onset CD, compared to other age-of-onset subtypes, is associated with individual risk factors such as neurological and cognitive deficits, poor emotion regulation, familial maladaptive parenting styles, and evocative family instability. While research has focused on dispositional risk factors for this heterogenous disorder, it is important to shift the focus to evidence-based clinical assessment and treatment strategies tailored to the poor prognosis of this subtype. Future research should examine current assessment sensitivity and appraise key stakeholders in early identification and treatment.
Conclusion: Early detection and intervention will increase the chances of a positive outcome for all parties, which includes reducing emotional strain and internalizing thoughts of caregivers and teachers and preventing antisocial personality disorder in adulthood. Normative treatment options for childhood-onset CD coincides with individual risk factors, further research will have implications in identifying and providing early care to at-risk children.
تقرير المخاطر العالمية 2023: المعرفة من أجل دعم السياسات واتخاذ القرار
Authors: Kazem Aboudouh Khaled
Published: March 2023

الرسائل الرئيسة
 تعتبر "أزمات ارتفاع تكلفة المعيشة" من أشد المخاطر العالمية التي سوف يواجهها قطاع كبير من سكان العالم خلال العامين المقبلين، وستبلغ ذروتها على المدى القريب.
 أدت الآثار الاقتصادية لجائحة كورونا والحرب في أوكرانيا إلى ارتفاع معدلات التضخم، وبدأت حقبة من النمو المنخفض، وتدهور الاستثمار؛ لذلك من المحتمل أن تواجه الحكومات والبنوك المركزية ضغوطًا تضخمية على مدار العامين المقبلين.
 يُحْتمل أن تصبح الحرب الاقتصادية هي القاعدة، مع تزايد الاشتباكات بين القوى العالمية وتَدَخُّل الدولة في الأسواق على مدى العامين المقبلين.
 قد يحمل المستقبل تزايدًا في التقلبات والمخاطر في مجالات متعددة ومتوازية، وهو ما يهدد الأمن في العديد من مناطق العالم، فقد تؤدي الصدمات المتزامنة والمخاطر المترابطة بشدة وتآكل القدرة على الصمود إلى زيادة خطر حدوث أزمات متعددة.
DNA Barcode of Homalomena pexa inferred from Internal Transcribed Spacer Region
Authors: Aprilianingsih Risqi , Farhatul Wahidah Baiq , Hariri Muhammad Rifqi
Published: March 2023

Homalomena pexa, a tomentose haired-leaf aroid, was a newly discovered and described plant species in early 2020. This species has currently only been reported from South Tapanuli. A molecular study to provide DNA sequence is essential in this preliminary investigation. This research aimed to characterize the barcode sequence of H. pexa and estimate the species' position in an Araceae phylogenetic tree. This research used ITS sequence to perform DNA barcoding on H. pexa. The sequencing result revealed that 1040 bp nucleotides were effectively amplified. The phylogenetic tree generated using the Neighbor-Joining method and the Kimura 2-parameter revealed that H. pexa clustered with H. atrox and H. humilis, with a bootstrap value of 97%. This investigation provided and demonstrated that ITS sequences could be used to validate and support the proper identification of Araceae species.
An Additional Information of Tarenna (Rubiaceae) in Madura Island
Authors: Indah Novita , Bagus Setiawan Ashari
Published: March 2023

Tarenna is a genus of relatives of Ixora which is found in forests. Tarenna is different from Ixora which is known as an ornamental plant. The purpose of this study was to find the genus Tarenna in Madura natural habitat to preserved or conserved before this genus became extinct. Observations were made on morphological characters. The morphological characteristics observed included: stature, stems, leaves, inflorescences, flowers, fruits, and seeds. Ixora has a corolla of various flowers while Tarenna only has a white corolla but smells good. Recent exploration and collection of Tarenna in Madura Island indicated that two species are a new record for Java and Madura Island, namely T. costata and T. fragrans. Existence of T. costata in this area not only as a new record for Madura Island, but also as a new record for Java. Tarenna fragrans was firstly reported in Madura Island as a new distributional record for this area. An updated of identification key, several descriptions, and documentations, as well as a distributional map are provided.
A Robust Deep Learning Approach for Distribution System State Estimation with Distributed Generation. (c2023)
Authors:   ,   Lebanese American University, Kfouri Ronald
Published: March 2023

Distribution System State Estimation (DSSE) remains a challenging problem due to the nature of distribution grids. Conventional methods, which are used to solve state estimation on the transmission level, require the grid to be observable. This is not directly applicable to distribution grids. In addition, the high integration of renewable energy introduces uncertainty, which makes the DSSE problem more complex. This work proposes a deep neural network approach that solves the DSSE problem with and without distributed generation, without using highly inaccurate pseudo-measurements. Due to the lack of public frameworks, we create a dataset that emulates real-life scenarios to train and test the neural network. Also, to evaluate the robustness of the algorithms, we test the neural network, without retraining it, on multiple scenarios with noisier data and bad data. The algorithms are tested on three different networks. The proposed approach solves the DSSE problem with limited measurements as inputs, which cannot be solved using conventional state estimation methods. Our approach also achieves highly accurate results, despite the additional noise introduced to the measurements.
Study Of Seljuq Textile Patterns. (c2023)
Authors:   ,   Lebanese American University, Al Sayegh Samah
Published: March 2023

The Seljuqs lived a luxurious life reflected in their art and how they dressed. They built a great Empire from Mesopotamia to Iran from the eleventh to the thirteenth centuries. The Seljuqs art held a harmonical balance between ancient Persian culture, Sunni Islamic norms, and Turkish steppe tradition. Due to the scarcity of the surviving material, we have a problem in studying Seljuq textiles. However, a great wealth of visual information was left to us through the mina’i wares, since they include patterns and colors. In my research, I focused on the depiction of garment patterns in the mina’i figures, in order to reconstruct the textile patterns. The patterns were common in almost all mediums including extant textiles, architecture, metalwork, glass, and miniatures. The four main elements of Islamic art were contained in Seljuq textiles, which were illustrated in mina’i figures.
The Survival and Continuity of Islamic Boarding School in the Era of Changes
Authors: Royani Ahmad , Hepni Hepni
Published: March 2023

The fast change requires the ability of Islamic boarding school to respond fast, rightly and adaptively. Using qualitative phenomenology, this study tries to see the phenomenon of changes faced by Islamic Boarding School of Nurul Islam Jember. The result of this study is that the adaptation of changes is done by the model of safeguarding and conserving the positive local values (localities) and useful for the Islamic boarding school. As agent of change, the Islamic boarding school of Nurul Islam participates in the societies’ change actively. Besides that, the cancelling of personality is to prepare santri to have the religion and non-religion knowledge to be Islamic human who can apply their knowledge. The personality built by Islamic boarding school of Nurul Islam is able to face and respond the changes without ignoring the morals (Akhlaq). In fact, the Islamic boarding school of Nurul Islam tries to integrate the formal school system and Islamic boarding school system to build the capable generations. The Islamic boarding school with soft skill and the formal school with life skill will be the solution of adaptive education in the era of changes.
Mediating Wasathiyah Islamic with Da’wah in the Public Sphere
Authors: Islam Nurul
Published: March 2023

This article focuses on mediating da'wah content through YouTube, packaged in the Islamic concept of wasathiyah. The rampant phenomenon of da'wah content leads to radicals & fundamentals, and even terror on social media causes public unrest. The public space is a space for equality, the emergence of discussions of public issues, and turning public activities and points into inclusive cultural commodities. This study uses a qualitative research method through social semiotic analysis’ Halliday of the object of research on the Jedanulis (based on specific content YouTube) and content analysis of the audience's comments to determine the behavior of users using Netlytic. This is done to determine the audience’s response (as a social media user) to the communicator Husain Jafar Alhadar. The representation of wasathiyah da'wah concludes with a point, which is a source. Ustaz is an actor who conveys divine teachings and promotes a positive image of Islam through inclusive practice in the public sphere. What they get as a message becomes a mirror for the listener. Ustaz is the message itself. Whether faith is good or bad is determined mainly by them. That Ustaz, including Ulama, is not mocking the ummah but inviting the ummah.
The Nationalism of Educators: A Case Study of the Nationalistic Insights of Teachers of MAN Cirebon Regency
Authors: Maliki Noval , Auliya Hilyatul , Murai Badawi , Hakim Lukman , Karyono Karyono
Published: March 2023

In this piece, the nationality of the Madrasah Aliyah Negeri (MAN) instructors in the Cirebon district is attempted to be captured. It is believed that some people's understanding of the national outlook has been compromised by the rapid flow of information and the waning of nationalism as an ideology. Teachers have emerged as crucial circles for inquiry from many national viewpoints as educated circles and agents of knowledge and values to pupils. This study employed qualitative approaches as its methodology. The findings indicated that MAN teachers in the Cirebon district had a very high nationality insight. In contrast, a teacher revealed in an interview that he was unfamiliar with the idea of the caliphate, which had been used to criticize the democratic system.
Increasing the Effectiveness of Pedagogical Technologies in Education: Psychological Experience of Technological Change Management
Authors: Kosov Mikhail E. , Malashenko Gevorg T. , Frumina Svetlana V. , Grishina Olga A. , Polyakova Olga A. , Alandarov Roman A. , Ponkratov Vadim V. , Shmigol Nataliya S. , Dzusova Svetlana S. , Abbood Abbas Abd Ali
Published: March 2023

This paper investigates the psychology of change management involving a technological change in the educational organization and the administrative and teaching staff. In particular, the paper delineates the staff’s psychological experience regarding the incorporation of pedagogical and educational technologies. In this regard, this article provides theoretical support based on the stimulus-organism-response theory, technological self-efficacy, and technological acceptance model and develops a theoretical model. A quantitative approach was applied to test the model, and research assumptions were drawn from the aforementioned theories. Particularly, disruptive statistics and correlation analysis were employed to test the assumption empirically by collecting data from 500 staff members. The research results highlight that a psychological response serves as the antecedent of the effectiveness of pedagogical and educational technologies, whereby the positive psychological responses (happiness, inspiration, or drive) would increase the effectiveness, while the negative psychological responses (anxiety, stress, and discomfort) would decrease it. This psychological response depends on the perceived self-efficacy and perceived ease of use of the staff, whose lower levels of the two raise the negative psychological response. Generally, to increase the effectiveness of pedagogical and educational technologies, it is essential to effectively manage the psychological well-being of the staff by reducing their negative psychological responses and developing their technological competence (self-efficacy and ability to use with ease). Doi: 10.28991/ESJ-2023-SIED2-05 Full Text: PDF
NOTES ON THE CONCEPT OF THE STATE BY N.M. KORKUNOV
Authors:   University of Rome Tor Vergata, Guarino Francesco
Published: March 2023

The essay is focused on studying the concept of the State that emerges in the late nineteenth century in the writings by N.M. Korkunov. After a brief biographical introduction, where the life and works of the jurist are recalled, his thought on the State is shortly explained in the context with that of the contemporary German jurisprudence. N.M. Korkunov excluded both the existence of a legal personality of the State and that of a single State will, considering them rather as mere legal fictions, since they were not phenomena proper to social life. Realist approach brought him to the understanding that the only phenomenon of reality that could not in any way constitute a fiction or an expedient of a legal nature would have been, if anything, the state domination, as the only element of the state concretely perceivable by man. The provided conclusions confirm the originality of his thinking from a methodological point of view. His methodological approach could perhaps allow him to be considered one of the fathers of the Sociology of Law
THREE GENERATIONS IN THE HISTORIOGRAPHICAL UNDERSTANDING OF THE RUSSIAN СHURCH-POLITICAL PRESENCE IN THE HOLY LAND, THE END OF THE 19TH - 21ST CENTURIES
Authors:   Smolensk State University, Kail Maksim V.
Published: March 2023

The article analyzes the historiographical situation in the field of the study of the Holy Land (Palestine) and the Russian cultural, religious and political presence in the region. It traces the dynamics of the study of the Holy Land in the context of Russian politics in the region is traced, from the experiences of self-determination in the middle – second half of the 19th century to the present. The specificity of the region is associated with the saturation of its religious, value and cultural meanings. Neither its remoteness nor other factors became an obstacle to the realization and historical understanding of the special Christian kinship of the Russian consciousness with the locos of the Holy Land. Its study got to be one of the significant directions of the national humanitarian thought in the late 19th – early 20th centuries. The analysis of the key works, plot and thematic lines in historiography revealed three generations in the study of the Holy Land associated with certain epochs in the history of Russia and the history of international (church-diplomatic) relations. The imperial period was characterized by a powerful popularization vector, the first experiments in the field of Christian archeology of the region. The post-Soviet return to the study of the region was characterized by attention to the study of the structures and institutions of the Russian presence in the region (the Russian Spiritual Mission, the Imperial Orthodox Palestinian Society). The modern generation of researchers is characterized by an interest in studying the realities of modern history, the objectification of the church-diplomatic factor in international relations of the post-war world.
DENG XIAOPING’S FOREIGN POLICY STRATEGY DURING THE PERIOD OF ECONOMIC REFORMS AND OPENNESS (LATE 1970S - 1990S)
Authors:   Far Eastern Federal University, Boyarkina Anna V.
Published: March 2023

The study of the diplomatic art of Chinese leadership proceeds to attract more and more attention of Russian and foreign researchers. The paper analyzes the foreign policy strategies and concepts of the second leader of the People’s Republic of China Deng Xiaoping in the late 1970s – 1990s. Undoubtedly, the first China’s leader Mao Zedong and then Deng Xiaoping both had a significant impact on the evolution of Chinese foreign relations strategy. It was these leaders who set their own models in the spirit of the era, effectively dividing the history of China’s foreign policy into two periods. The famous concept “Taking low profile and trying not to show yourself in any way” strategy proposed by Deng Xiaoping leads to the formulation and development by Jiang Zemin, the Chinese leaders of the third generation, the concept of “peaceful rise”, which then became “peaceful development”, Hu Jintao’s “soft power” and “harmonious world” and other modern concepts of foreign policy. The leading approach to the study of the issue is the historical and comparative method. It appears that not all foreign policy strategies or theories of Deng Xiaoping have moved from simplistic generalizations, hypotheses to reliable analytical conclusions or solid concepts. Only Xi Jinping is beginning to shape holistic concepts in the full sense of the word. The main task of foreign policy concepts is to generalize and reveal the general patterns of international life and China’s foreign policy.
A Comprehensive Experimental Study on The Performance of Alcoholalkoxyl-Sulfate-Based Surfactant: A Case Study on Light Crude Oil Field A
Authors: Fauzi M.
Published: March 2023

An energy operator in Indonesia planned an exploration well that required two divergent hole opening sections: A 12 ¼” x 13 ½” hole section; and a 10 ⅜” x 12 ¼” hole section, to be able to add 11 ¾” liner between the 13 ⅜” and 9 ⅝” casing to address the subsurface uncertainties that are typical of an exploration well, and as such a new generation of Bi-Center bit was utilized. This project required the application of multiple innovative approaches: 1) The opening tool has to pass through the minimum or ID of the wellhead and casing; 2) Possess the capacity to be inserted into BHA design such as rotary or using mud motor; 3) The necessity to efficiently drill the cemented shoe track; 4) The minimization of rat hole needs to be eliminated to optimize and ensure cementing of the casing. Simultaneous drilling and hole enlargement were conducted in a way that achieved the intended objectives in a cost-efficient and effective manner. Before the project, a pre-job planning exercise was performed to ensure that the Bi-Center bit could pass through the maximum tool size allowance in conjunction with mud motor BHA. The 12 ¼” x 13 ½” Bi-Center bit was successfully drilled and enlarged to the programmed target depth, with a total interval length of 453 m and a satisfactory ROP. There were no issues while tripping the BHA through the wellhead wear bushing, the casing, and subsequently drilled the cement shoe track, float equipment, and casing shoe.The next section of the well experienced a successful run of the 10 ⅜” x 12 ¼” Bi-Center with a respectable ROP and the bit was graded in good dull condition after it was pulled out of the hole. Both the 11 ¾” liner and 9 ⅝” casing strings were successfully deployed to the bottom and demonstrated that the Bi-Center bits provided satisfactory hole quality.
Rig Hours Optimization Using Plug Modification on Fracturing Job in Sangasanga Field
Authors: Hidayat T.R.
Published: March 2023

Sangasanga Field is one of 22 fields in PT. Pertamina EP with oil production target of 5670 BOPD in 2019. The Field well work plan includes 32 wells workover and 77 well intervention which are expected to support the achievement of production targets in 2019. One of the jobs to support well intervention is to test tubing before cementing and fracturing process. In the tubing test process, there are activities that contribute to high loss time, namely circuit unplugging. Objective of this paper is to find an alternative solution to minimize the activity of running in and pulling out the circuit to open the plug by modifying the plug using a TH pump shoe (tubing pump) and a TH pump mandrel (tubing pump) and a series of fishing tools: on and off (fishing neck), pony rod 7/8” with guide sucker rod so that the circuit is in the middle of the fishing jar to help release both the plug and sinker bar. The working method is the shoe and pump mandrel that have been plugged in run together with run tubing, a pressure test is carried out per 20 joints to the depth according to the program, after the final pressure test is carried out, then the fishing tool circuit to the sandline is connected, then run sandline until plug peak. On-off combined with a pony rod and rod guide will ensure the fishing tool is in the middle of the inner diameter of tubing, then it will latch into the plug and conduct tension sandline so that the jar will work and the plug modification tool will release from shoe. Modification of these tools reduces the pull-in work and is tested on 4 wells, the result is that it can reduce the tubing pull-in time for 12 hours also generate efficiency in rig rental costs and diesel costs of $1,550/well. With this innovation, it can accelerate the operation of the rig work so that it can potentially increase the well production in the Sangasanga Field.
The First Successful Installation of Metal-to-Metal, Gas-Tight Casing Reconnect System to Reinstate Exploration Well to Production
Authors: Sudirman M.H.
Published: March 2023

The S-3 and S-4 exploration wells in S Field in indonesia, were drilled in 2015 and 2016, respectively, and subsequently permanently plugged and abandoned. Positive result from production analysis and the exploration program led to the decision to convert these exploration wells into production wells. The exploration phase was completed with 13 3/8-in and 9 5/8-in casing strings, which were left cut off on the seabed during the plug and abandonment program. The objective of the well construction program was to restore well integrity by reconnecting the cut-off casings to surface with full metal-to-metal seal integrity. In Aaddition, the new connection must withstand the high axial loading conditions presented by the application with no loss of internal diameter and ensuring future completion program flexibility. The metal-to-metal, gas-tight sealing and high axial load rating criteria would need to be addressed to follow local regulatory requirements as well as to meet full well operating parameters. Several options, such as a mudline suspension system, external casing patch, and the drilling of a new well, were provided for this well construction program. An innovative metal-to-metal, gas-tight casing reconnect system was found to be the most effective and efficient solution to address the challenge. The existing 13 3/8-in and 9 5/8-in casing in the wells was cut and dressed to ensure the casing reconnect receptacle could be placed over the casing stump. The setting tool was then deployed at a predetermined depth using a reliable method to ensure accurate placement inside the receptacle. The setting tool was used to perform hydraulic expansion of the existing casing inside the casing reconnect receptacle to create sealing points. This solution provided both wells with a fully anchored metal-to-metal seal that was tested and found to meet full well operating parameters. The completion strings were installed without any issues.
Draining The Last Challenging Shallow Resources By Redefining and Optimizing Barrier System in Deep Zone Wells
Authors: Abidiy I
Published: March 2023

The most optimum way to combat production decline is to open all possible reservoirs from existing wells. The same-layer reservoirs had been produced since long time ago as it is the easiest way, remaining the challenging across-layer zones, mostly shallower zones. However, most of existing wells do not fit for purpose in producing shallow zones, especially in well integrity point of view. Pilot test initially has been performed with full mitigation to produce the well without jeopardizing well integrity. However, the initial trial was too complex. This study develops fit-for-purpose mitigation in order to enable operation scalability and improve economic viability in order to perform large volume of operation and normal scope of budget. This study maintains key precautions while eliminating excessive mitigations. Key precautions to be maintained are good isolation assurance and routine well integrity monitoring. Lean mitigation applied consists of using fit-for-purpose well intervention vessel while maintaining readiness of heavy intervention barge with pressure bleed off and well killing capability. Annulus pressure anomaly will be investigated in the occurrence instead of implementing mitigations such as noise log and bleed off line installation as default operations. This lean procedure has been implemented in 4 wells. These wells could flow up to 2.6 million standard cubic feet per day (MMscfd) with total contribution at 0.4 billion standard cubic feet (BCF) and still continue flowing. No integrity issue observed after this new procedure implementation. This study showed that in order to open the possibility to produce shallow reservoirs, the method has to be validated first. Optimization only possible to be performed only if the trial has been successfully performed. On the other hand, the simple method is not possible to be performed in the first place since it will impose high risk and high uncertainty situation.
Successful Remedial of Collapsed Conductor Pipe With Collision Issue in Offshore Jack Up Operation
Authors: Feizal A.H.
Published: March 2023

In 2020-2021, a drilling campaign was planned in Santan Field as further development of the field. Five wells were proposed including Well-31 to drill from a crowded fixed-platform built in 138ft water depth. New slots was fabricated between the existing wells since platform extension or side track was not feasible at the time, resulting dense well spacing on the surface: 1meter form center-to-center and 0.7 meter between wall-to-wall. The 20”, X-56, and 0.625” WT conductor pipe (CP) was driven vertically by diesel hammer with construction barge prior to rig arrival on the platform. When drilling operations commenced, the 17.5 inch drilling BHA was held up during CP cleaning out. The pipe was suspected collapsed as metal cuttings return to surface. According to hammering job history and projection from actual survey, the hypothesis was that the CP was collapsed due to collision with adjacent wells during piling job. A remedial method was established to repair the collapsed CP with the objectives to open the CP to certain diameter without compromising the integrity of the collided well as the pipes were suspected in contact each other. The main risk of interrupting well integrity of producing well are loss of asset and more fundamentally well control event. A modifications was also required on top section by applying hole-enlargement technology and using flush-joint casing to achieve the same casing size on the production section as the original plan. This paper describes the key strategies in safe CP remedial in a unique collision situation. The methods prevent the company from wasting available well slot and from damaging a valuable asset in a risky job situation. From production and field development perspective, the successful remedial was valuable to keep the well delivered as per target.