bluuebunny/crossref_metadata_2025 huggingface dataset:
Multifunctional twelve port frequency agile diversity antenna for indoor wireless applications
Authors: Thangarasu Deepa , Palaniswamy Sandeep Kumar , Thipparaju Rama Rao , Alzaidi Mohammed S. , Kumar Sachin , Elkamchouchi Dalia H.
Published: May 2023

The recent resurgence of new-generation reconfigurable technologies delivers a plethora of various applications in all public, private and enterprise solutions over the globe. In this paper, a frequency reconfigurable polarization and pattern diverse Multiple-Input-Multiple-Output (MIMO) antenna is presented for indoor scenarios. The MIMO antenna is comprised of twelve radiating elements, and polarization and pattern diversity is obtained by arranging them in three different planes: Horizontal Plane (HP), Vertical Plane-I (VP-I), and Vertical Plane-II (VP-II). The proposed antenna operates in mode I (wideband) and mode II (multiband), by combining two different radiators using PIN diodes. The antenna dynamically switches between Mode I (wideband) and mode II (multiband). Mode, I cover the ultra-wideband (UWB) range from 2.3 to 12 GHz, while mode II covers GSM (1.85–1.9 GHz), Wi-Fi and LTE-7 (2.419–2.96 GHz), 5G (3.15–3.28 GHz and 3.45–3.57 GHz), public safety WLAN (4.817–4.94 GHz), and WLAN (5.11–5.4 GHz) frequency bands. The peak gain and efficiency of the MIMO antenna are 5.2 dBi and 80%, respectively.
Spirulina platensis improves growth, oil content, and antioxidant activitiy of rosemary plant under cadmium and lead stress
Authors: Gharib Fatma Abd El Lateef , Ahmed Eman Zakaria
Published: May 2023

In the present study, a pot experiment was conducted to investigate the response of rosemary (Rosmarinus officinalis L.) plants to foliar application of Spirulina platensis at 0.0, 0.1, 0.2, and 0.4%; soil irrigation with heavy metals (Cd nitrate, Pb acetate, and Cd + Pb, each at 100 ppm), and Spirulina platensis at 0.1% + heavy metals. Spirulina platensis significantly improved growth parameters, oil yield/fed, photosynthetic pigments, and activity of superoxide dismutase (SOD), glutathione reductase (GR), catalase (CAT), and polyphenol oxidase (PPO) with a maximum promoting effect at 0.2% algal extract. On the other hand, heavy metal stress reduced growth criteria, photosynthetic pigments, and oil yield, while, significantly increased levels of antioxidant enzymes (SOD, CAT, GR) and corresponding non-enzymatic antioxidants (ascorbic acid, total antioxidant capacity, phenolics and flavonoids). Bioaccumulation factor (BF) and translocation factor (TF) indicated that Cd and Pb accumulated largely in the roots, with little transfer to the shoots. Nevertheless, compared with heavy metal treatments, S. platensis at 0.1% significantly increasing growth parameters, oil content, photosynthetic pigments, and the activity of non-enzymatic and enzymatic antioxidants, while, slightly reduced TF of Cd and Pb, alleviated membrane lipid peroxidation, and significantly lowered the content of malondialdehyde, hydrogen peroxide, and indole acetic acid oxidase (IAAO) activity in heavy metal (Cd, Pb, and Cd + Pb)-treated rosemary plants.
NT-proBNP as a surrogate for unknown heart failure and its predictive power for peripheral artery disease outcome and phenotype
Authors: Zierfuss Bernhard , Feldscher Anna , Höbaus Clemens , Hannes Antonia , Koppensteiner Renate , Schernthaner Gerit-Holger
Published: May 2023

Patients with peripheral artery disease (PAD) are at high risk of excess mortality despite major improvements in multimodal pharmacotherapy for cardiovascular disease. However, little is known about co-prevalences and implications for the combination of heart failure (HF) and PAD. Thus, NT-proBNP as a suggested surrogate for HF was evaluated in symptomatic PAD regarding long-term mortality. After approval by the institutional ethics committee a total of 1028 patients with PAD, both with intermittent claudication or critical limb ischemia were included after admission for endovascular repair and were followed up for a median of 4.6 years. Survival information was obtained from central death database queries. During the observation period a total of 336 patients died (calculated annual death rate of 7.1%). NT-proBNP (per one standard deviation increase) was highly associated with outcome in the general cohort in crude (HR 1.86, 95%CI 1.73–2.01) and multivariable-adjusted Cox-regression analyses with all-cause mortality (HR 1.71, 95%CI 1.56–1.89) and CV mortality (HR 1.86, 95% CI 1.55–2.15). Similar HR’s were found in patients with previously documented HF (HR 1.90, 95% CI 1.54–2.38) and without (HR 1.88, 95%CI 1.72–2.05). NT-proBNP levels were independently associated with below-the-knee lesions or multisite target lesions (OR 1.14, 95% CI 1.01–1.30). Our data indicate that increasing NT-proBNP levels are independently associated with long-term mortality in symptomatic PAD patients irrespective of a previously documented HF diagnosis. HF might thus be highly underreported in PAD, especially in patients with the need for below-the-knee revascularization.
Structural integrity assessment of Inconel 617/P92 steel dissimilar welds for different groove geometry
Authors: Kumar Amit , Pandey Chandan
Published: May 2023

The work is focused on examining the effect of the weld groove geometry on microstructure, mechanical behaviour, residual stresses and distortion of Alloy 617/P92 steel dissimilar metal weld (DMW) joints. Manual multi-pass tungsten inert gas welding with ERNiCrCoMo-1 filler was employed to fabricate the DMW for two different groove designs: Narrow V groove (NVG) and Double V groove (NVG). The microstructural examination suggested a heterogeneous microstructure evolution at the interface of the P92 steel and ERNiCrCoMo-1 weld, including the macrosegregation and element diffusion near the interface. The interface structure included the beach parallel to the fusion boundary at the P92 steel side, the peninsula connected to the fusion boundary and the island within the weld metal and partially melted zone along Alloy 617 fusion boundary. An uneven distribution of beach, peninsula and island structures along the fusion boundary of P92 steel was confirmed from optical and SEM images of interfaces. The major diffusion of the Fe from P92 steel to ERNiCrCoMo-1 weld and Cr, Co, Mo, and Ni from ERNiCrCoMo-1 weld to P92 steel were witnessed from SEM/EDS and EMPA map. The Mo-rich M6C and Cr-rich M23C6 phases were detected in inter-dendritic areas of the weld metal using the weld’s SEM/EDS, XRD and EPMA study, which formed due to the rejection of Mo from the core to inter-dendritic locations during solidification. The other phases detected in the ERNiCrCoMo-1 weld were Ni3(Al, Ti), Ti(C, N), Cr7C3 and Mo2C. A variation in the microstructure of weld metal from top to root and also along the transverse direction in terms of composition and dendritic structure and also due to the composition gradient between dendrite core and inter-dendritic areas, a significant variation in hardness of weld metal was observed from both top to root and also in the transverse direction. The peak hardness was measured in CGHAZ of P92 while the minimum was in ICHAZ of P92 steel. Tensile test studies of both NVG and DVG welds joint demonstrated that failure occurred at P92 steel in both, room-temperature and high-temperature tensile tests and ensured the welded joint’s applicability for advanced ultra-supercritical applications. However, the strength of the welded joint for both types of joints was measured as lower than the strength of the base metals. In Charpy impact testing of NVG and DVG welded joints, specimens failed in two parts with a small amount of plastic deformation and impact energy of 99 ± 4 J for the NVG welds joint and 91 ± 3 J for the DVG welded joint. The welded joint met the criteria for boiler applications in terms of impact energy (minimum 42 J as per European Standard EN ISO15614-1:2017 and 80 J as per fast breeder reactor application). In terms of microstructural and mechanical properties, both welded joints are acceptable. However, the DVG welded joint showed minimum distortion and residual stresses compared to the NVG welded joint.
Monitoring and analysis of ground subsidence in Shanghai based on PS-InSAR and SBAS-InSAR technologies
Authors: Zhang Zhihua , Hu Changtao , Wu Zhihui , Zhang Zhen , Yang Shuwen , Yang Wang
Published: May 2023

Shanghai is susceptible to land subsidence due to its unique geological environment and frequent human activities. Traditional leveling techniques are not sufficient for monitoring large areas of land subsidence due to the time-consuming, labor-intensive, and expensive nature of the process. Furthermore, the results of conventional methods may not be timely, rendering them ineffective for monitoring purposes. Interferometric Synthetic Aperture Radar (InSAR) technology is a widely used method for monitoring ground subsidence due to its low cost, high efficiency, and ability to cover large areas. To monitor the surface sink condition of Shanghai over the past 2 years, monitoring data were obtained through the technical processing of 24 images from Sentinel-1A data covering Shanghai from 2019 to 2020 using the Persistent Scatterer (PS-InSAR) and Small Baseline Subset (SBAS-InSAR) technique. The ground subsidence (GS) results were extracted via PS and SBAS interferometry processing, while Shuttle Radar Topography Mission data were used to correct the residual phase. According to PS and SBAS methods, the maximum ground subsidence in the study area reached 99.8 mm and 47.2 mm, respectively. The subsidence rate and the accumulated amount of subsidence derived from the monitoring results revealed the urban area in Shanghai to be principally characterized by uneven GS, with multiple settlement funnels being found to be distributed across the main urban area. Moreover, when compared with the historical subsidence data, geological data, and urban construction distribution data, the individual settlement funnels were observed to correspond to those data concerning the historical surface settlement funnel in Shanghai. By randomly selecting GS time-series data regarding three feature points, it was determined that the morphological variables of the GS remained largely consistent at all time points and that their change trends exhibited a high degree of consistency, which verified the reliability of the PS-InSAR and SBAS-InSAR monitoring method. The results can provide data support for decision making in terms of geological disaster prevention and control in Shanghai.
Essential oil yield and compositions of Dracocephalum moldavica L. in intercropping with fenugreek, inoculation with mycorrhizal fungi and bacteria
Authors: Amiriyan Chelan Zahra , Amini Rouhollah , Dabbagh Mohammadi Nasab Adel
Published: May 2023

Intercropping is one of the most important components of sustainable agriculture. The effects of chemical fertilizer (CF), arbuscular mycorrhizal fungi (AMF) (Glomus sp.) and AMF + nitrogen-fixing bacteria (NFB) including Azospirillum and Azotobacter (AMF + NFB) was studied on essential oil yield and compositions of Moldavian balm (Mb) (Dracocephalum moldavica L.) in sole cropping and intercropping with fenugreek (F) (Trigonella foenum-graecum L.). The experiment was conducted during 2020 and 2021 growing seasons in East Azarbayhan, Iran. The highest dry herbage yield (6132 kg ha−1) was obtained in Mb:F(4:2) and CF treatment. After sole Moldavian balm, the highest essential oil yield (15.28 kg ha−1) was obtained in Mb:F (4:2) and AMF + NFB treatment. Geranial, geranyl acetate, geraniol, neral, and nerol were the main chemical constituents of essential oil. In AMF + NFB treatments the geranial contents in intercropping patterns of Mb:F (1:1), (2:2) and (100:50), increased by 25.1, 15.5 and 34.6% compared with sole Moldavian balm. The highest LERT values were observed in Mb:F (100:50) cropping pattern in 2021 (1.70 and 1.63 for CF and AMF + NFB treatments). Generally, it can be concluded that Mb:F (100:50) intercropping and use of AMF + NFB bio-fertilizer could be recommended to medicinal plant growers in sustainable production systems.
Novel stereological method for estimation of cell counts in 3D collagen scaffolds
Authors: Zavadakova Anna , Vistejnova Lucie , Belinova Tereza , Tichanek Filip , Bilikova Dagmar , Mouton Peter R.
Published: May 2023

Current methods for assessing cell proliferation in 3D scaffolds rely on changes in metabolic activity or total DNA, however, direct quantification of cell number in 3D scaffolds remains a challenge. To address this issue, we developed an unbiased stereology approach that uses systematic-random sampling and thin focal-plane optical sectioning of the scaffolds followed by estimation of total cell number (StereoCount). This approach was validated against an indirect method for measuring the total DNA (DNA content); and the Bürker counting chamber, the current reference method for quantifying cell number. We assessed the total cell number for cell seeding density (cells per unit volume) across four values and compared the methods in terms of accuracy, ease-of-use and time demands. The accuracy of StereoCount markedly outperformed the DNA content for cases with ~ 10,000 and ~ 125,000 cells/scaffold. For cases with ~ 250,000 and ~ 375,000 cells/scaffold both StereoCount and DNA content showed lower accuracy than the Bürker but did not differ from each other. In terms of ease-of-use, there was a strong advantage for the StereoCount due to output in terms of absolute cell numbers along with the possibility for an overview of cell distribution and future use of automation for high throughput analysis. Taking together, the StereoCount method is an efficient approach for direct cell quantification in 3D collagen scaffolds. Its major benefit is that automated StereoCount could accelerate research using 3D scaffolds focused on drug discovery for a wide variety of human diseases.
A holistic and proactive approach to forecasting cyber threats
Authors: Almahmoud Zaid , Yoo Paul D. , Alhussein Omar , Farhat Ilyas , Damiani Ernesto
Published: May 2023

Traditionally, cyber-attack detection relies on reactive, assistive techniques, where pattern-matching algorithms help human experts to scan system logs and network traffic for known virus or malware signatures. Recent research has introduced effective Machine Learning (ML) models for cyber-attack detection, promising to automate the task of detecting, tracking and blocking malware and intruders. Much less effort has been devoted to cyber-attack prediction, especially beyond the short-term time scale of hours and days. Approaches that can forecast attacks likely to happen in the longer term are desirable, as this gives defenders more time to develop and share defensive actions and tools. Today, long-term predictions of attack waves are mostly based on the subjective perceptiveness of experienced human experts, which can be impaired by the scarcity of cyber-security expertise. This paper introduces a novel ML-based approach that leverages unstructured big data and logs to forecast the trend of cyber-attacks at a large scale, years in advance. To this end, we put forward a framework that utilises a monthly dataset of major cyber incidents in 36 countries over the past 11 years, with new features extracted from three major categories of big data sources, namely the scientific research literature, news, blogs, and tweets. Our framework not only identifies future attack trends in an automated fashion, but also generates a threat cycle that drills down into five key phases that constitute the life cycle of all 42 known cyber threats.
Circulating miR-146b and miR-27b are efficient biomarkers for early diagnosis of Equidae osteoarthritis
Authors: Yassin Aya M. , AbuBakr Huda O. , Abdelgalil Ahmed I. , Farid Omar A. , El-Behairy Adel M. , Gouda Eman M.
Published: May 2023

One of the most orthopedic problems seen in the equine is osteoarthritis (OA). The present study tracks some biochemical, epigenetic, and transcriptomic factors along different stages of monoiodoacetate (MIA) induced OA in donkeys in serum and synovial fluid. The aim of the study was the detection of sensitive noninvasive early biomarkers. OA was induced by a single intra-articular injection of 25 mg of MIA into the left radiocarpal joint of nine donkeys. Serum and synovial samples were taken at zero-day and different intervals for assessment of total GAGs and CS levels as well as miR-146b, miR-27b, TRAF-6, and COL10A1 gene expression. The results showed that the total GAGs and CS levels increased in different stages of OA. The level of expression of both miR-146b and miR-27b were upregulated as OA progressed and then downregulated at late stages. TRAF-6 gene was upregulated at the late stage while synovial fluid COL10A1 was over-expressed at the early stage of OA and then decreased at the late stages (P < 0.05). In conclusion, both miR-146b and miR-27b together with COL10A1 could be used as promising noninvasive biomarkers for the very early diagnosis of OA.
General anesthesia with propofol during oocyte retrieval and in vitro fertilization outcomes: retrospective cohort study
Authors: Haikin Herzberger Einat , Levy Omri , Sun Bei , Miller Netanella , Rahav Roni , Dana Elad , Raviv Shaul , Hershko-Klement Anat , Wiser Amir
Published: May 2023

General anesthesia is frequently administered during oocyte retrieval. Its effects on the outcomes of IVF cycles are uncertain. This study investigated whether administration of general anesthesia (specifically propofol) during oocyte retrieval affects IVF outcomes. A total of 245 women undergoing IVF cycles were included in this retrospective cohort study. IVF outcomes of 129 women who underwent oocyte retrieval under propofol anesthesia and 116 without anesthesia were compared. Data were adjusted for age, BMI, estradiol on triggering day and total gonadotropin dose. The primary outcomes were fertilization, pregnancy and live birth rates. A secondary outcome was the efficiency of follicle retrieval associated with the use of anesthesia. Fertilization rate was lower in retrievals under anesthesia compared to without (53.4% ± 34.8 vs. 63.7% ± 33.6, respectively; p = 0.02). There was no significant difference in the ratio of expected to retrieved oocytes between retrievals with and without anesthesia (0.8 ± 0.4 vs. 0.8 ± 0.8, respectively, p = 0.96). The differences in pregnancy and live birth rates between the groups were not statistically significant. General anesthesia administered during oocyte retrieval may have adverse effects on the fertilization potential of oocytes. This impact on the developmental potential of oocytes may lead to negative IVF outcomes and should be investigated further.
Integrating metabolomics and network pharmacology to assess the effects of quercetin on lung inflammatory injury induced by human respiratory syncytial virus
Authors: Sun Ya-Lei , Zhao Pei-Pei , Zhu Cheng-Bi , Jiang Ming-Chen , Li Xin-Min , Tao Jia-Lei , Hu Chan-Chan , Yuan Bin
Published: May 2023

Quercetin (QR) has significant anti-respiratory syncytial virus (RSV) effects. However, its therapeutic mechanism has not been thoroughly explored. In this study, a lung inflammatory injury model caused by RSV was established in mice. Untargeted lung tissue metabolomics was used to identify differential metabolites and metabolic pathways. Network pharmacology was used to predict potential therapeutic targets of QR and analyze biological functions and pathways modulated by QR. By overlapping the results of the metabolomics and the network pharmacology analyses, the common targets of QR that were likely to be involved in the amelioration of RSV-induced lung inflammatory injury by QR were identified. Metabolomics analysis identified 52 differential metabolites and 244 corresponding targets, while network pharmacology analysis identified 126 potential targets of QR. By intersecting these 244 targets with the 126 targets, hypoxanthine–guanine phosphoribosyltransferase (HPRT1), thymidine phosphorylase (TYMP), lactoperoxidase (LPO), myeloperoxidase (MPO), and cytochrome P450 19A1 (CYP19A1) were identified as the common targets. The key targets, HPRT1, TYMP, LPO, and MPO, were components of purine metabolic pathways. The present study demonstrated that QR effectively ameliorated RSV-induced lung inflammatory injury in the established mouse model. Combining metabolomics and network pharmacology showed that the anti-RSV effect of QR was closely associated with purine metabolism pathways.
Role of decomposition products in the oxidation of cyclohexene using a manganese(III) complex
Authors: Zand Zahra , Mousazade Younes , Arevalo Ryan Lacdao , Bagheri Robabeh , Mohammadi Mohammad Reza , Bikas Rahman , Chernev Petko , Aleshkevych Pavlo , Vandichel Matthias , Song Zhenlun , Dau Holger , Najafpour Mohammad Mahdi
Published: May 2023

Metal complexes are extensively explored as catalysts for oxidation reactions; molecular-based mechanisms are usually proposed for such reactions. However, the roles of the decomposition products of these materials in the catalytic process have yet to be considered for these reactions. Herein, the cyclohexene oxidation in the presence of manganese(III) 5,10,15,20-tetra(4-pyridyl)-21H,23H-porphine chloride tetrakis(methochloride) (1) in a heterogeneous system via loading the complex on an SBA-15 substrate is performed as a study case. A molecular-based mechanism is usually suggested for such a metal complex. Herein, 1 was selected and investigated under the oxidation reaction by iodosylbenzene or (diacetoxyiodo)benzene (PhI(OAc)2). In addition to 1, at least one of the decomposition products of 1 formed during the oxidation reaction could be considered a candidate to catalyze the reaction. First-principles calculations show that Mn dissolution is energetically feasible in the presence of iodosylbenzene and trace amounts of water.
Salvage of ribose from uridine or RNA supports glycolysis in nutrient-limited conditions
Authors: Skinner Owen S. , Blanco-Fernández Joan , Goodman Russell P. , Kawakami Akinori , Shen Hongying , Kemény Lajos V. , Joesch-Cohen Lena , Rees Matthew G. , Roth Jennifer A. , Fisher David E. , Mootha Vamsi K. , Jourdain Alexis A.
Published: May 2023

Glucose is vital for life, serving as both a source of energy and carbon building block for growth. When glucose is limiting, alternative nutrients must be harnessed. To identify mechanisms by which cells can tolerate complete loss of glucose, we performed nutrient-sensitized genome-wide genetic screens and a PRISM growth assay across 482 cancer cell lines. We report that catabolism of uridine from the medium enables the growth of cells in the complete absence of glucose. While previous studies have shown that uridine can be salvaged to support pyrimidine synthesis in the setting of mitochondrial oxidative phosphorylation deficiency1, our work demonstrates that the ribose moiety of uridine or RNA can be salvaged to fulfil energy requirements via a pathway based on: (1) the phosphorylytic cleavage of uridine by uridine phosphorylase UPP1/UPP2 into uracil and ribose-1-phosphate (R1P), (2) the conversion of uridine-derived R1P into fructose-6-P and glyceraldehyde-3-P by the non-oxidative branch of the pentose phosphate pathway and (3) their glycolytic utilization to fuel ATP production, biosynthesis and gluconeogenesis. Capacity for glycolysis from uridine-derived ribose appears widespread, and we confirm its activity in cancer lineages, primary macrophages and mice in vivo. An interesting property of this pathway is that R1P enters downstream of the initial, highly regulated steps of glucose transport and upper glycolysis. We anticipate that ‘uridine bypass’ of upper glycolysis could be important in the context of disease and even exploited for therapeutic purposes.
Biochar nanoparticles alleviate salt stress in tomato (Solanum lycopersicum) seedlings
Authors: Tao Ran , Zhang Yinlong , Yang Jing , Yang Tianxi , White Jason C. , Shen Yu
Published: May 2023

With the root application of biochar nanoparticles, the crops can present higher resistance to the salt stress in the environment.
Highly efficient determination of Mn2+ in Chinese liquor by using a novel electrochemical sensor based on TiO2-NH2@covalent organic framework nanocomposites
Authors: Yu Liangyun , Sun Liangju , Zhang Qi , Zhang Jingjing , Yang Bairen , Huang Mingquan , Zhou Yawen , Xu Baocai , Hu Xiaoya
Published: May 2023

This study developed an electrochemical sensor for Mn2+ assay in Baijiu based on TiO2-NH2@COFDPTB nanocomposite, which was synthesized via the controllable growth of COFDPTB onto the surface of TiO2-NH2 using the Schiff-base condensation reaction.
Injectable biomaterial induces regeneration of the intervertebral disc in a caprine loaded disc culture model
Authors: Snuggs Joseph W. , Emanuel Kaj S. , Rustenburg Christine , Janani Ronak , Partridge Simon , Sammon Christopher , Smit Theo H. , Le Maitre Christine L.
Published: May 2023

Here, the efficacy of an injectable hydrogel system (NPgel), either alone or together with progenitor cells, was investigated within a degenerate loaded disc model. NPgel inhibited cellular catabolism and promoted anabolism, supporting regeneration.
Bortezomib-loaded mixed micelles realize a “three-in-one” effect for enhanced breast cancer treatment
Authors: Liu Jianhao , Xu Xiaoman , Li Yanying , Xu Jingxia , Zhao Ruogang , Liu Siwei , Wu Jingliang , Zhang Li , Zhang Bo
Published: May 2023

BTZ-LGs can achieve a “three-dimensional synergistic” effect in terms of killing tumor cells, suppressing CAFs, and improving immune responses.
Designed ankyrin repeat proteins for detecting prostate-specific antigen expression in vivo
Authors: Gut Melanie , Dreier Birgit , Furler Sven , Sobek Jens , Plückthun Andreas , Holland Jason P.
Published: May 2023

Prostate specific antigen binding Designed Ankyrin Repeat Proteins (DARPins) were selected and C-terminally conjugated for Gallium-68 radiolabelling. Two of the developed tracers showed specific uptake in mouse prostate tumour models.
Enhanced electrochemical CO2reduction performance of cobalt phthalocyanine with precise regulation of electronic states
Authors: Yao Tong , Zhang Lu-Hua , Zhan Jiayu , Zhou Zhixiang , You Yang , Zhang Zisheng , Yu Fengshou
Published: May 2023

CoPc/R-GQD was synthesized by a simple strategy. Benefiting from the high density of functional groups that can be provided by GQDs and the strong electron-donation property of –NH2, the examined CoPc/NH2-GQDs achieved a 100% FECO.
Multilayer directionally arranged silver nanowire networks for flexible transparent conductive films
Authors: Guo Zhijiang , Li Xiaoli , Li Ning , Liu Xuanji , Li Haojie , Li Xuezhi , Wang Yuxuan , Liang Jianguo , Chen Zhanchun
Published: May 2023

Silver nanowire (AgNW) networks have excellent optoelectronic properties and have important applications in various optoelectronic devices.
Improved photoelectrocatalytic performances over electrochemically reduced WO3: implications of oxygen vacancies
Authors: Liu Yunni , Yao Wang , Lin Jun
Published: May 2023

The raised Fermi level achieves a substantial electron trap effect of the oxygen vacancies and bends upward the band at the WO3/electrolyte interface, contributing to the transfer and separation of photoinduced charges for enhanced PEC performances.
Enhanced thermal assisted photocatalysis reduction of carbon dioxide over a Fe2−xGaxO3 solid solution
Authors: Lin Lingtong , Xing Danning , Zhang Caiyun , Liu Yuanyuan , Wang Zeyan , Wang Peng , Zheng Zhaoke , Cheng Hefeng , Dai Ying , Huang Baibiao
Published: May 2023

The CO evolution rate of Fe1.96Ga0.04O3 is about 2.4 times that of pure Fe2O3. The introduction of Ga changes the electron spin state in CB, from spin up for Fe2O3 to spin down for Fe2−xGaxO3, resulting in the suppression of electron decay in VB.
Modeling molecular ensembles with gradient-domain machine learning force fields
Authors: Maldonado Alex M. , Poltavsky Igor , Vassilev-Galindo Valentin , Tkatchenko Alexandre , Keith John A.
Published: May 2023

Gradient-domain machine learning (GDML) force fields show excellent accuracy, data efficiency, and applicability for molecules, and a many-body approach opens the possibility of increased transferability to molecular ensembles.
Tentacle-like core–shell CoNi2S4/C3N4 bifunctional electrocatalysts for efficient overall alkaline water splitting
Authors: Li Qingfei , Li Nan , Wu Mianmian , Sun Guifang , Shen Wenjing , Shi Minghao , Ma Jiangquan
Published: May 2023

Stable and efficient bifunctional electrocatalysts are of great significance for sustainable energy conversion and human society sustainability.
Titanium dioxide and table sugar enhance the leaching of silver out of nanosilver packaging
Authors: Yang Tianxi , Adhikari Laxmi , Paulose Teena , Bleher Reiner , Duncan Timothy V.
Published: May 2023

TiO2 and sugar cooperatively enhance the quantity and alter the form of silver that migrates out of nanosilver-enabled plastic food packaging under intended use conditions.
Singlet oxygen formation in non-aqueous oxygen redox chemistry: direct spectroscopic evidence for formation pathways and reliability of chemical probes
Authors: Mondal Soumyadip , Jethwa Rajesh B. , Pant Bhargavi , Hauschild Robert , Freunberger Stefan A.
Published: May 2023

We have shown direct spectroscopic evidence of the previously identified pathways for singlet oxygen (1O2) formation in non-aqueous oxygen redox chemistry.
Extra virgin coconut oil (Cocos nucifera L.) intake shows neurobehavioural and intestinal health effects in obesity-induced rats
Authors: Araújo de Vasconcelos Maria Helena , Tavares Renata Leite , Dutra Maria Letícia da Veiga , Batista Kamila Sabino , D'Oliveira Aline Barbosa , Pinheiro Rafael Oliveira , Pereira Ramon de Alencar , Lima Marcos dos Santos , Salvadori Mirian Graciela da Silva Stiebbe , de Souza Evandro Leite , Magnani Marciane , Alves Adriano Francisco , Aquino Jailane de Souza
Published: May 2023

The present study aimed to evaluate the effect of E-VCO on neurobehaviour and intestinal health parameters of obesity-induced rats.
The development and validation of a non-invasive prediction model of hyperuricemia based on modifiable risk factors: baseline findings of a health examination population cohort
Authors: Chen Shuo , Han Wei , Kong Linrun , Li Qiang , Yu Chengdong , Zhang Jingbo , He Huijing
Published: May 2023

This study aims to establish a simple and non-invasive risk prediction model for hyperuricemia in Chinese adults based on modifiable risk factors.
Identification of macrocyclic peptides which activate bacterial cylindrical proteases
Authors: Walther Raoul , Westermann Linda M. , Carmali Sheiliza , Jackson Sophie E. , Brötz-Oesterhelt Heike , Spring David R.
Published: May 2023

This work reports a divergent peptide stapling strategy to identify macrocyclic peptides which increase the proteolytic activity of the proteolytic core of the caseinolytic protease.
Anti-proliferative activity of nitroquinolone fused acylhydrazones as non-small cell human lung cancer agents
Authors: Nandakumar Vandana , Sundarasamy Amsaveni , Adhigaman Kaviyarasu , Ramasamy Sentamil Selvi , Paulpandi Manickam , Kodiveri Muthukaliannan Gothandam , Narayanasamy Arul , Thangaraj Suresh
Published: May 2023

Reporting anti-cancer active 8-nitroquinolone fused acyl hydrazones towards A549 cell lines using fluorescence apoptotic detection and cell cycle analysis.
Microneedle system with light trigger for precise and programmable penetration
Authors: Yu Weijiang , Shen Jieze , Ji Chong , Zhang Peng , Chang Hao , Wang Youxiang , Ji Jian
Published: May 2023

Light-triggerd microneedle system for controllable insertion.
Giant enhancement of the initial SERS activity for plasmonic nanostructures via pyroelectric PMN-PT
Authors: Shao Mingrui , Liu Di , Lu Jinxuan , Zhao Xiaofei , Yu Jing , Zhang Chao , Man Baoyuan , Pan Hui , Li Zhen
Published: May 2023

This paper presents a pyroelectric PMN-PT composite plasmonic Ag NP SERS substrate, whose initial SERS signal is further greatly enhanced under the action of a pyroelectric potential, with a dominant chemical mechanism.
Design, synthesis, molecular docking and biological evaluation of 1,2,4-triazole derivatives possessing a hydrazone moiety as anti-breast cancer agents
Authors: Tapera Michael , Kekeçmuhammed Hüseyin , Tunc Cansu Umran , Kutlu Aybuke Ulku , Çelik İsmail , Zorlu Yunus , Aydin Omer , Sarıpınar Emin
Published: May 2023

A set of 1,2,4-triazoles containing a hydrazone moiety was synthesized by oxidative cyclization utilizing molecular iodine under mild conditions. These compounds were evaluated as anticancer agents and their binding mechanism was investigated.
Multifunctional nanomicelles constructedviaan aggregation and de-aggregation strategy for magnetic resonance/NIR II fluorescence imaging-guided type I photodynamic therapy
Authors: Wang Lirong , Qi Ji , Zhang Ke , Zhuang Zeyan , Ding Keke , Chen Xu , Shan Hong , Ding Dan , Qin Anjun , Tang Ben Zhong
Published: May 2023

This work demonstrated that the aggregation and de-aggregation strategy of AIEgens in nanomicelles is very attractive for constructing multifunctional theranostic probes.
A reductive Sandmeyer-type reaction for the synthesis of sulfoxides from anilines under photocatalysis
Authors: Peng Gangqi , Cheng Hao , Cheng Xiya , He Yang , An Yuanyuan , Wu Jie , Zheng Danqing
Published: May 2023

A reductive Sandmeyer-type sulfinylation reaction of aryldiazonium salts with sodium sulfinates is reported, affording a range of valuable sulfoxides in a radical substitution pathway.
Iron-catalyzed cross-electrophile coupling of bromostyrenes and chlorosilanes
Authors: Lin Ying , Zou Liang , Bai Renren , Ye Xiang-Yang , Xie Tian , Ye Yang
Published: May 2023

An efficient Fe-catalyzed cross-electrophile vinyl silylation protocol is reported for the first time. A set of 1,4-diene silanes are conveniently synthesized from simple vinyl chlorosilanes and alkenyl bromides under mild reductive conditions.
Red, green, and blue radio-luminescent polymer dots doped with heteroleptic tris-cyclometalated iridium complexes
Authors: Liu Zouyue , Nguyen Hieu Thi Minh , Asanuma Daiki , Tojo Sachiko , Yamaji Minoru , Kawai Kiyohiko , Pratx Guillem , Fujitsuka Mamoru , Osakada Yasuko
Published: May 2023

In this study, we synthesized radioexcitable luminescent polymer dots (P-dots) doped with heteroleptic tris-cyclometalated iridium complexes that emit red, green, and blue light.
Renewable synthesis of γ-butyrolactone from biomass-derived 2-furanone using palladium supported on humin-derived activated carbon (Pd/HAC) as a heterogeneous catalyst
Authors: Vinod Nivedha , Dutta Saikat
Published: May 2023

A palladium catalyst supported on humin-derived activated carbon produced γ-butyrolactone and γ-valerolactone from 2-furanone and angelica lactone, respectively, in excellent yields.
Optimizing dissolved gas composition in a double-bath-type sonoreactor for efficient production of ultrasonic-activated water with stable oxygen and nitrogen reactive species
Authors: Le Bao-Ngoc T. , Nguyen Nguyen-Phuong , Duong Thanh-Linh H. , Nguyen Tri , Hoang Tien-Cuong , Nguyen Hong-Ha T. , Vo Dai-Viet N. , Nguyen Hoang-Duy P. , Pham Thuy-Phuong T.
Published: May 2023

Plasma-activated water (PAW), which mainly contains reactive oxygen and nitrogen species, has recently gained considerable attention due to its potential applications in disinfection of food and sustainable agriculture.
Unprecedented energy storage in metal–organic complexes via constitutional isomerism
Authors: Kottaichamy Alagar Raja , Deebansok Siraprapha , Deng Jie , Nazrulla Mohammed Azeezulla , Zhu Yachao , Bhat Zahid Manzoor , Devendrachari Mruthyunjayachari Chattanahalli , Vinod Chathakudath Prabhakaran , Nimbegondi Kotresh Harish Makri , Fontaine Olivier , Thotiyl Musthafa Ottakam
Published: May 2023

Non-covalent interaction governed supercapacitive energy storage in metal–organic complexes.
Bioethanol, internal combustion engines and the development of zero-waste biorefineries: an approach towards sustainable motor spirit
Authors: Barua Shaswat , Sahu Debojeet , Sultana Firdous , Baruah Swagata , Mahapatra Sadhan
Published: May 2023

This review article describes the generations of bioethanol and their sustainability. Furthermore, the compatibility of bioethanol blended fuels with motor engines is described. Also, approaches towards zero-waste biorefineries are highlighted.
Construction of p-nitropyrazole-1,3,4-triazole framework energetic compounds: towards a series of high-performance heat-resistant explosives
Authors: Li Chengchuang , Zhu Teng , Lei Caijin , Cheng Guangbin , Xiao Chuan , Yang Hongwei
Published: May 2023

In this study, a series of explosives based on the DPT framework were synthesized. Among all the compounds, DPTO, DPPT, DPBT and PBPT exhibit excellent thermal stabilities with the Td over 300 °C, while their detonation velocity exceeds 8700 m s−1.
An interfacial covalent bonding coupled ultrafine CuS-nanocrystals/MXene heterostructure for efficient and durable magnesium storage
Authors: Cheng Zhi , Xu Yanan , Zhang Xudong , Peng Qifan , Wang Kai , Zhang Xiong , Sun Xianzhong , An Qinyou , Mai Liqiang , Ma Yanwei
Published: May 2023

A robust CuS/d-Ti3C2Tx heterojunction was constructed through a confined in situ growth strategy, which significantly improved its magnesium storage performances.
A highly stretchable and sensitive strain sensor for lip-reading extraction and speech recognition
Authors: Cheng Lin , Ruan Diqing , He Yongwei , Yang Jiayao , Qian Wei , Zhu Longwei , Zhu Pindie , Wu Huaping , Liu Aiping
Published: May 2023

CuNWs-rGO/PDMS strain sensors attached around the lips can be used for lip-reading extraction and recognition, helping people with speech impairment to live a happy life.
Regulating charge carrier extraction and transport with dual-interface modification for efficient perovskite solar cells
Authors: Ye Weitao , Du Zhentao , Ou Deliu , Tu Jielei , Shang Ming-Hui , Zhou Jiahui , Wang Lin , Yang Weiyou , Yang Zuobao
Published: May 2023

We report an efficient dual-interface modification strategy to improve the charge carrier management with GABr and NH4F. As a result, the target perovskite solar cells attain a decent PCE of 19.61% with a remarkably enhanced fill factor of 78.34%.
Controlled phase-separation effect for enhanced optical refrigeration in yttrium-aluminosilicate glasses
Authors: Meyneng Thomas , Thomas Jyothis , Grégoire Nicolas , Leelapornpisit Weawkamol , Valdez Jesus , Kashyap Raman , Messaddeq Younès
Published: May 2023

This study reports the demonstration of optical refrigeration in Yb doped yttrium-aluminosilicate glasses, showing near-unity quantum efficiencies anti-Stokes fluorescence, allowing net optical refrigeration up to −2.4 K under atmospheric pressure.
Maternal immune activation and role of placenta in the prenatal programming of neurodevelopmental disorders
Authors: Woods Rebecca M. , Lorusso Jarred M. , Fletcher Jennifer , ElTaher Heidi , McEwan Francesca , Harris Isabella , Kowash Hager M. , D'Souza Stephen W. , Harte Michael , Hager Reinmar , Glazier Jocelyn D.
Published: May 2023

Maternal infection during pregnancy, leading to maternal immune activation (mIA) and cytokine release, increases the offspring risk of developing a variety of neurodevelopmental disorders (NDDs), including schizophrenia. Animal models have provided evidence to support these mechanistic links, with placental inflammatory responses and dysregulation of placental function implicated. This leads to changes in fetal brain cytokine balance and altered epigenetic regulation of key neurodevelopmental pathways. The prenatal timing of such mIA-evoked changes, and the accompanying fetal developmental responses to an altered in utero environment, will determine the scope of the impacts on neurodevelopmental processes. Such dysregulation can impart enduring neuropathological changes, which manifest subsequently in the postnatal period as altered neurodevelopmental behaviours in the offspring. Hence, elucidation of the functional changes that occur at the molecular level in the placenta is vital in improving our understanding of the mechanisms that underlie the pathogenesis of NDDs. This has notable relevance to the recent COVID-19 pandemic, where inflammatory responses in the placenta to SARS-CoV-2 infection during pregnancy and NDDs in early childhood have been reported. This review presents an integrated overview of these collective topics and describes the possible contribution of prenatal programming through placental effects as an underlying mechanism that links to NDD risk, underpinned by altered epigenetic regulation of neurodevelopmental pathways.
Providing Mindful and Informed Health Care for Patients Who Are LGBTQ+: Perspectives for Clinical Audiology
Authors: Kirjava Shade Avery , Sladen Douglas P. , DeBacker J. Riley
Published: May 2023

Purpose:

More than 7% of the U.S. population identifies as LGBTQ+ (lesbian, gay, bisexual, transgender, queer, and other identities), meaning clinical audiologists in all settings are likely to encounter LGBTQ+ patients seeking audiological services. This conceptual clinical focus article (a) introduces contemporary LGBTQ+ terms, definitions, and pertinent issues; (b) summarizes the current state of knowledge on barriers to equitable hearing health care access and utilization for people who identify as LGBTQ+; (c) explores the legal, ethical, and moral obligations for audiologists to provide equitable care to people who identify as LGBTQ+; and (d) provides resources to continue to learn about salient LGBTQ+ issues.

Conclusions:

This clinical focus article provides actionable guidance to clinical audiologists on providing inclusive equitable care to LGBTQ+ patients. Practical actionable guidance on how clinical audiologists can make their clinical practice more inclusive for their patients who identify as LGBTQ+ is provided.
Screening for Auditory Processing Disorder in French-Speaking School-Age Children: A Pilot Study
Authors: Duquette-Laplante Fauve , Duval Jérémie , Pelletier Marie-Pier , Darche Patricia , Fuente Adrian , Jutras Benoît
Published: May 2023

Objectives:

A few clinical screening tools for auditory processing disorder (APD) are currently available. However, most of these tools are in English and cannot be used to screen individuals with a first language other than English. This study aimed to develop an APD screening test battery in French and to assess its psychometric properties in detecting school-age children at risk of APD.

Method:

Prior to their complete audiological APD assessment, 53 children (7–12 years old) were recruited from an audiology clinic. The APD assessment lasted between 2 and 3 hr, including 15–20 min for the screening test battery. The screening test battery was composed of four behavioral subtests and two questionnaires (parent and teacher).

Results:

When combined, two among the four behavioral subtests showed a sensitivity of 100% and a specificity of 80%.

Conclusion:

The newly developed screening tool could help reduce the number of unnecessary APD assessments, therefore allowing early diagnosis in children with APD and increasing their chances of receiving adequate intervention.
Perceptions of Racism and White Privilege Among White Graduate Students in Audiology and Speech-Language Pathology
Authors: Williams Liliana , Ebert Kerry Danahy
Published: May 2023

Purpose:

In the White-dominated fields of audiology and speech-language pathology, graduate students should demonstrate awareness of racism and racial privilege to begin developing cultural humility. A 2013 survey of graduate students in audiology and speech-language pathology indicated that White students demonstrated minimal awareness of White privilege (Ebert, 2013). This study builds on Ebert (2013) by investigating changes in White students' perceptions of White privilege over time and by adding characterization of their perceptions of systemic racism.

Method:

A web-based survey was distributed to graduate students in audiology and speech-language pathology programs across the country. The survey combined repeat questions from the work of Ebert (2013) with novel questions on systemic racism within the fields. For this study, only responses from White students were analyzed.

Results:

The majority of White respondents (
n
= 104) acknowledged White privilege and systemic racism, though colorblindness and denial were still present among student responses. Significant increases in acknowledgment of White privilege from the Ebert (2013) results were observed across all questions. In qualitative analyses, the most common themes were the impact of White privilege and systemic racism on quality of services, access and opportunities, and clinician–client mismatch.

Conclusions:

Among White audiology and speech-language pathology graduate students, awareness of White privilege has increased over the past decade and most students acknowledge this privilege, as well as systemic racism. However, additional steps should be taken by students, graduate training programs, and practicing clinicians to continue confronting racial inequities in the fields.

Supplemental Material:

https://doi.org/10.23641/asha.22714222
Acoustic and Perceptual Categorization of Sibilants for Mandarin Children With Ankyloglossia
Authors: Luo Shan , Min Ye , Meng Zhibing , Ji Rui
Published: May 2023

Purpose:

To deepen our understanding of the effects of ankyloglossia on articulation, the purpose of this study is to examine consonant production and the perceived accuracy of Mandarin-speaking children with ankyloglossia.

Method:

Ten tongue-tie (TT) and 10 typically developing (TD) children produced nine Mandarin sibilants that contrast in three places of articulation. Their speech productions were analyzed from six acoustic measurements. To further examine the perceptual consequences, an auditory transcription task (
N
= 21) was conducted.

Results:

The acoustic analyses discovered that the TT children failed to distinguish the three-way place contrast and produced significant acoustic deviations compared with the TD peers. The perceptual transcription results found that TT children's production was significantly misidentified, suggesting severely affected intelligibility.

Conclusions:

The preliminary findings provide strong support for a correlation between ankyloglossia and distorted speech signals and suggest important interactions between sound errors and linguistic experience. We also propose that ankyloglossia should not be a purely appearance-based diagnosis and that speech production is a crucial index of tongue function in clinical decision making and monitoring.
The Contribution of Phonological Processing to Reading and Spelling in Students With Cochlear Implants
Authors: Werfel Krystal L. , Hendricks Alison Eisel
Published: May 2023

Purpose:

Children with cochlear implants (CIs) have difficulty with literacy, and although it is established that phonological processing underlies literacy skills in children with typical hearing (TH), the relation of phonological processing and literacy in children with CIs is not fully understood. This study evaluated the contributions of phonological processing to word-level reading and spelling skills of children with CIs.

Method:

Thirty children with CIs and 31 children with TH in Grades 3 through 6 completed measures of word reading, spelling, and phonological processing. The contributions of phonological processing (phonological awareness, phonological memory, and phonological recoding) to reading and spelling were evaluated.

Results:

Children with CIs scored lower across measures of reading, spelling, phonological awareness, and phonological memory, but not phonological recoding, than children with TH. Phonological processing components were significant predictors of reading and spelling for children with CIs but not for children with TH.

Conclusions:

This study underscores the important contribution of phonological processing, particularly phonological awareness and phonological memory, in literacy development for children who use CIs. These results suggest an urgent need for research into not only the underlying mechanisms that predict literacy outcomes but also evidence-based interventions to support these students' literacy.