bluuebunny/crossref_metadata_2025 huggingface dataset:
Modeling an urban highway: A statistical physics point of view for a nonphysical system
Authors: Castro González L. , Lárraga M.E. , Antonio del Rio And J.
Published: July 2019

Nowadays, methodologies coming from studying physical systems are being applied to the description of a wide variety of complex systems. In particular, one can study thermodynamical methods to describe the overall behavior of many systems, independent of the precise microscopic construction. In this paper, a real Mexican highway is studied as a cellular automata system using available official data released by the Mexican Government. The system studied is the Cuernavaca bypass which was modified in 2016. Official data allows to compare the highway before and after the modifications. As more complex thermodynamic variables such as entropy is difficult to define and measure in discrete traffic models, it is shown how other more simple variables such as the standard deviation can be enough to have a complete analysis of the system. More specifically, it is shown how standard deviation can be seen as a measure of order. Results from the study of the highway show how, taking a minimal measure such as ordering the transit of heavy trucks can reduce up to 30\% the travel time from one end to another. Otherwise, travel times stays practically constant with respect to the original system.
Teaching strategy for introducing beginners to Coherent States
Authors: Plastino A. , Rocca And M.C.
Published: July 2019

Handling coherent states by undergraduates students may be a hard task, as they have to deal with Glauber's series $e^{-\frac {|\alpha|^2} {2}}\sum\limits_{n=0}^\infty\frac {\alpha^n} {\sqrt{n!}}\phi_n(x)$. We show here that the task can be greatly simplified by introduction of a novel compact formula for Glauber coherent states employed in [ Int. J. Mod. Phys. B {\bf 31} (2017) 175051]. This expression is obtained by solving the basic differential equation associated to coherent states $a|\alpha>=\alpha|\alpha>$.
Mujeres fumadoras y su asociación con atipia del cérvix uterino en Las Tunas, Cuba
Authors: Pérez Castillo Raydel , Cordero González Yoanne , Del Río Boullón Tania
Published: July 2019

Introducción: Las atipias del cérvix uterino se definen como alteraciones  del tamaño, forma y núcleo de las células epiteliales. El tabaquismo se asocia a la persistencia de la infección del virus del papiloma humano y a la progresión al cáncer cervicouterino. El objetivo es identificar la correlación entre el tabaquismo y las atipias celulares de cérvix uterino. Métodos: Se realizó un estudio descriptivo, correlacional, retrospectivo en 235 mujeres con diagnósticos de atipias celulares  por test de Papanicolaou desde de enero de 2013 a marzo de 2019. Se analizaron las variables edad, primeras relaciones sexuales, resultados citológicos y consumo de tabaco. Se determinó la asociación estadística por la prueba de Chi cuadrado y Coeficiente de Spearman para un nivel de significación de (p<0,05). Resultados: La media de edades fue de 37,5 ±10,4 con primeras relaciones sexuales a los 16±1,9 años. Predominaron  las atipias de bajo grado NIC-1 (n=115; 48,94%) y NIC-2 (n=76; 32,34%). Las mujeres fumadoras (n=82; 34,89%) como promedio presentaron un consumo diario de 12,60 cigarrillos, con un historial de 11,3 años y  7,8 cajetillas anuales. La mayor correlación estuvo entre los tipos de lesiones y el índice tabáquico (Rho Spearman 0,84; p<0,0001). Conclusión: Mujeres en edad fértil con inicio precoz de sus relaciones sexuales son más propensas a presentar atipias del cérvix. En las mujeres ha aumentado la adicción al tabaco y el diagnóstico de las atipias del cérvix en los últimos años. En mujeres fumadoras existe un ciclo gradual con tendencia a lesiones de alto grado. La severidad de las lesiones presenta correlación y proporcionalidad directa ante el consumo anual de cigarrillos.
A Social Impact Bond (SIB) : A Shariah Appraisal
Authors: Ahmad Mahadi Umar , Bambale Yahaya Yunusa , Adam Zain Mahamad Ibrahim
Published: July 2019

Social Impact Bond (SIB) is a funding mechanism for social projects whereby the payment for the projects is anchored on meeting the outcome metrics, otherwise the investors risk losing their money. The mechanism emerged since 2010 in the United Kingdom and has quickly spread to other parts of the world. In the past, there has not been any popular fatwā on this mechanism from a Sharīʿah point of view.  Therefore, this article will examine the funding and payment arrangement and then conduct takyif fiqhi (jurisprudential adaptation) to ascertain the degree of Sharīʿah compliance and determine the most appropriate Islamic contract most suitable under the arrangement. The article adopts qualitative method of research by making in-depth analysis of Islamic contracts including the primary and secondary sources of Islamic law. It also relied on literature on SIB from conventional point of view and internet materials. Major findings of the research show that SIB, whilst its pay-for-success mechanism does not contain ribā, it contains excessive gharar. The excessive gharar, however, was found ineffective to void al-jaʿālah-based SIB and hibah li thawāb which is the second contract similar to SIB. This is because of hājah and element of gratuity respectively.
What Makes a Law “Islamic”? A Preliminary Study on the Islamicity of Laws in Malaysia
Authors: Wan Muhammad Ramizah
Published: July 2019

There exists a good deal of misunderstanding regarding laws in general. Some laws are categorised as civil or common laws even though their contents are Islamic while others are labelled Islamic but they fail to meet the standards required by Islamic law. This article discusses the characteristics, which make a law, “Islamic”. Based on a content analysis of the revealed sources, the opinion of the majority of Muslim scholars, and the relevant court cases, this study argues that a law does not become Islamic by merely claiming it to have been derived from or somehow related to the divine revelation. It is true that for any law to be Islamic, it must indeed be based upon the divine revelation, and supported by Muslim jurists. Nevertheless, it must also simultaneously be promoting justice for everyone, irrespective of race, religion, gender, social, economic or political status. The law must also be of benefit to all mankind and not only to the Muslims. Finally, the law must fulfil the requirements of MaqāÎid al-sharÊ‘ah (objectives of the law). Judged as such, most of the Malaysian laws may be considered  to be Islamic, by nature. These aspects have not been given due attention by many scholars, which leads either to the condemnation of all laws in Malaysia as secular or as un-Islamic. This fact alone justifies the need for a study to provide guidelines to judge the Islamicity of a certain law, which is done herein.
GAMBARAN PENGGUNAAN OBAT DAN TINGKAT KONTROL ASMA PADA PASIEN ASMA DEWASA RAWAT JALAN DI BKPM MAGELANG PERIODE FEBUARI-MARET 2016
Authors: Astuti Whiliani Indra , Hapsari Widarika , Lutfiyati Heni
Published: July 2019

Asma merupakan penyakit inflamasi kronik saluran pernapasan. Saat ini diperkirakan sekitar 100-150 juta penduduk di dunia menderita asma, jumlah ini diperkirakan akan terus bertambah hingga mencapai 180.000 orang setiap tahunnya. Tingginya prevalensi asma yang terjadi, maka dibutuhkan perhatian khusus dalam penggunaan obat untuk meningkatkan tingkat kontrol asma pada pasien asma. Penelitian ini bertujuan untuk mengetahui penggunaan obat dan tingkat kontrol asma pada pasien asma rawat jalan di Balai Kesehatan Paru Masyarakat Magelang.Penelitian ini merupakan penelitian deskriptif, pengambilan data dilakukan dengan resep pasien asma secara prospektif dan dilakukan pendekatan non eksperimental dengan pengamatan secara tidak langsung menggunakan kuesioner ACT untuk mengetahui tingkat kontrol asma. Sampel dalam penelitian ini berjumlah 46 responden, pengambilan sampel menggunakan tehnik purposive sampling. Hasil penelitian disajikan dalam bentuk tabel disertai pembahasan. Pasien asma yang paling banyak yaitu perempuan berjumlah 30 orang (65%), sedangkan laki-laki berjumlah 16 orang (35%). Distribusi pasien asma terbanyak pada kelompok umur 42-47 tahun (24%) dan umur 48-53 tahun (20%). jenis obat yang banyak digunakan di BKPM Magelang untuk pengobatan asma yaitu obat agonis β2 adrenergik (47,41%). Pasien asma yang tidak terkontrol sebanyak 24 orang (52%), dan yang terkontrol sebagian sebanyak 22 orang (48%).
EFEKTIFITAS ANTIBAKTERI Staphylococcus aureus EKSTRAK RIMPANG TEMU HITAM (CURCUMA AERUGINOSA ROXB) DARI KECAMATAN KENDAL
Authors: Ariyanti Ariyanti
Published: July 2019

ABSTRAK

Rimpang temu hitam merupakan tanaman dengan khasiat sebagai antibakteri.Penelitian ini bertujuan untuk mengetahui efektifitas antibakteri ekstrak rimpang temu hitam terhadap bakteri staphylococcus aureus.Metode yang digunakan dalam penelitian ini adalah metode kualitatif dan metode difusi sumuran. Uji efektifitas antibakteri terbentuk zona bening pada media yang diukur menggunakan jangka sorong.

            Hasil penelitian menunjukan bahwa temu hitam dapat menghambat bakteri staphylococcus aureus. Rata – rata zona bening yang diukur dengan jangka sorong pada konsentrasi 15% yaitu 7,10 mm, konsentrasi 20% yaitu 12,21 mm dan konsentrasi 25% yaitu 15,19 mm. Hasil analisa statistik uji mann whitney didapatkan nilai signifikasi antara masing – masing konsentrasi yaitu 0,000 dimana nilai tersebut < 0,05 maka H0 ditolak, artinya ada perbedaan rata – rata antara konsentrasi tersebut. Hasil analisa statistik uji t-test antara konsentrasi 20% dan konsentrasi 25% didapatkan nilai signifikasi 0,103 dimana nilai tersebut > 0,05, maka H0 diterima, artinya tidak ada perbedaan rata – rata antara konsentrasi tersebut. Hal tersebut menunjukan bahwa konsentrasi efektif yang memiliki efektifitas antibakteri adalah 20%.

 

Kata kunci :Ekstrak rimpang temu hitam, Efektifitas Antibakteri,Staphylococcus aureus

 

ABSTRACT

Curcuma aeruginosa is a plant with antibacterial properties. This research is to know the antibacterial efectifity of Curcuma aeruginosa extract against staphylococcus aureus bacteria. Method used in this research is qualitative method and diffusion method of wells. The antibacterial activity test is formed of clear zone on the medium measured using the sliding term.The results showed that the Curcuma aeruginosa can inhibit staphylococcus aureus bacteria. The average clear zone measured by the sliding term at 15% concentration is 7.10 mm, the concentration of 20% is 12.21 mm and the concentration of 25% is 15.19 mm. The result of statistical analysis of mann whitney test showed significance value between each concentration that is 0.000 where in <0.05 then H0 rejected, there is average difference between the concentration. Test statistic t test between concentration 20% and concentration of 25% got significance value 0,103 where with this> 0,05, then H0 accepted, there is no difference mean between the concentration. This suggests that an effective concentration having antibacterial efectifity is 20%. Keywords: Curcuma aeruginosa extract, Efectifity Antibacterial, Staphylococcus aureus
Вплив блокаторів рецепторів ангіотензину II на зміни артеріального тиску при добовому моніторуванні залежно від ранкового або вечірнього прийому
Authors: Rekovets O. L. , Sirenko Yu. M. , Torbas O. O. , Kushnir O. O. , Prymak G. F.
Published: July 2019

The aim – to evaluate the effect of angiotensin II receptor blockers olmesartan, azilsartan and telmisartan when administered in the morning or evening hours on blood pressure (BP) indices during daily monitoring in patients with arterial hypertension (AH).Materials and methods. The study involved 126 patients with mild to moderate hypertension who were selected to compare the effect of angiotensin II receptor blockers – olmesartan, azilsartan and telmisartan – in the morning and evening hours. They were divided into 6 groups: 20 patients taking olmesartan at a dose of 20–40 mg in the morning, 20 patients taking olmesartan at a dose of 20–40 mg in the evening, 21 patients taking azilsartan at a dose of 40–80 mg in the morning, 20 patients taking azilsartan at a dose of 40–80 mg in the evening, 22 patients taking telmisartan at a dose of 40–80 mg in the morning, 23 patients taking telmisartan at a dose of 40–80 mg in the evening. Patients underwent primary examination and repeated one – after 3 months of therapy.Results and discussion. Evening reception of olmesartan, compared with morning one, led to a more pronounced decrease in diurnal systolic blood pressure (SBT) – (11.09±2.30) vs (4.06±2.25) mm Hg (p<0.01). Changes in diurnal diastolic blood pressure (DBP) were statistically insignificant, although its decrease during evening reception was more significant compared to decrease during morning reception ((8.38±2.58) mm Hg versus (3.38±2.31) mm Hg). Changes in daily blood pressure against reception of azilsartan in the evening and morning hours were statistically significant, but did not differ from each other ((13.06±2.65)/(9.76±1.73) vs. (12.71±1.62)/(7.00±1.50) mm Hg). Reduction of diurnal blood pressure at the background of telmisartan administration was statistically significantly more pronounced in the morning than in the evening intake ((16.48±2.86)/(12.56±2.80) vs. (4.93±1.53)/(5.40±1.89) mm Hg, p<0.01). Thus, morning reception more significantly lowered the average daily blood pressure against the background of taking telmisartan, and the evening reception – against the background of taking olmesartan. Azilsartan equally reduced the blood pressure both at evening and morning admission. The rate of achievement of target BP at daily monitoring against the background of the administration of olmesartan, azilsartan and telmisartan was 71.80; 71.0 and 75.61 %, respectively.Conclusions. Admission of telmisartan more significantly reduced the average daily blood pressure in morning hours compared to evening hours, olmesartan better lowered the average daily blood pressure when taken in the evening, and the use of azilsartan equally affected the decrease in blood pressure regardless of the time of taking the drug.
Сердечная недостаточность, требующая госпитализации, у пациентов, перенесших кардиохирургическое вмешательство по поводу клапанной патологии сердца
Authors: Zhadan A. V.
Published: July 2019

The aim – to determine the factors associated with the frequency of hospitalizations for decompensation of heart failure (HF) after cardiac surgery in patients with valvular heart disease.Materials and methods. 235 patients who underwent cardiac surgery for valvular heart disease were examined. During the period from 2014 to 2017, a part of patients (129 people) had no hospitalizations, while 106 people were on inpatient treatment from 1 to 10 times, on average 2.78±1.95. The complex of examination of patients along with physical examination included electrocardiography, echocardiography.Results and discussion. During dynamic observation for 2 years in the group of patients without hospitalization, a progressive statistically significant decrease in the size of the left atrium (LA) and left ventricle (LV) as well as an increase in LV contractility were noted, while in the group of patients after hospitalization such changes were not observed. The dimensions of the chambers of the heart remained practically unchanged for 2 years. Thus, it can be concluded that the more severe course of heart failure after prosthetics of heart valves is accompanied by the absence of reverse remodeling of the heart chambers. Predictors of hospitalizations for HF are the presence of diabetes mellitus, hypertension and permanent form of atrial fibrillation.Conclusions. The probability of progression of heart failure in patients after cardiosurgical intervention for valvular heart pathology is not affected by sex, age, type of lesion of the valve, etiology of valve damage, indicators of echocardiography. Predictors of hospitalizations for heart faiure in the long-term postoperative period are the presence of diabetes, AF, and AH. The more severe course of heart failure after prosthetics of heart valves is accompanied by the absence of reverse remodeling of the heart chambers.
Regression mathematical model of two-stage combined electrical technology of high-temperature convective drying and ozone-air grain processing
Authors: Pahomov V. I , Gazalov V. S , Buhancov K. N
Published: July 2019

Large production of cereal crops in Russia in 2014-2018 (100-130 million tons) imply the need to dry 10-30 % of the crop collected annually in the country to ensure its quantitative and qualitative preser-vation. The main way to reduce the excess moisture of grain in the Russian Federation is high-temperature convective drying, but it refers to very energy-intensive technological operations and, therefore, is very expensive. In the context of the constant increase in energy prices in the Russian economy, the country's agricultural producers face the primary task of increasing the profitability of the grain industry, within which it is necessary to reduce material costs at all stages of production, including through the creation of new high-intensity energy-saving technologies and technical means for drying grain raw materials. The authors have developed a two-stage technology of high-temperature convective and ozone-air grain drying that meets these requirements. In the article, based on the analysis of the parametric scheme of the convective-ozone-air moisture removal method, compiled taking into account the conditions and possibilities of conducting experimental studies of the process at the industrial drying unit «ELEKTA-1» of small productivity, the optimization parameters of this process are defined, which are: reduction of the drying time and the total reduction in energy consumption, in addition, the main factors varied in the ex-periments are highlighted: the initial moisture content of the grain, the amount of ozone supply to 1 m3 of grain and time spent on moisture removal. Second-order regression mathematical models for the convec-tive-ozone-air drying of barley grain with different initial humidity (30, 25 and 20 %) have been developed and their statistical significance has been evaluated. An analysis of the experimental data of the combined drying options studied at 6 % moisture removal for one cycle of processing the grain material revealed the following parameters of the efficiency of the methods of convective ozone-air moisture removal: when drying grain with an initial humidity of 30 %, the process duration decreased by 28 % and the total energy consumption decreased amounted to 33-43 %; when drying grain with a moisture content of 25 %, the duration of the process is reduced by 19 %, energy consumption by 24-35 %; and when drying grain with a moisture content of 20 %, the duration of the process is reduced by 30-35 %, energy consumption by 35-40 %.
EXPERIMENTAL IDENTIFICATION OF PLASTICITY AND FAILURE LAWS OF ANISOTROPIC LOW-CARBON SHEET STEEL FOR COLD FORMING MODELING
Authors: Adamov A. A. , Keller I. E. , Petukhov D. S.
Published: July 2019

To formulate a mathematical model of cold sheet forming of thin-walled products, an experimental method is proposed for identifying defining relations of plastic yield of anisotropic sheet low-carbon steel DC04EK. The experimental studies were done on a Zwick Z100/SN5A multipurpose floor-mounted test stand with a maximal testing force of 100 kN at a temperature of 20°С. Longitudinal strain was registered with a Multisens long-run longitudinal strain gage. To measure transversal strain, a manual DMS strain gage was used, which was located between the test rods of a Multisens extensionmeter. To determine the elasticity modulus, yield strength, plastic anisotropy coefficient, to construct a deformational hardening curve and to determine points of a limiting deformation curve, specimens in the form of straps with parallel edges, cut out of a sheet at angles of 0, 45 and 90° relative to the rolling direction, were tested in uniaxial tension at room temperature. Based on the obtained data, parameters of Barlat's yield function Yld 2000-2d were determined. To describe a deformational hardening curve with a yield plateau, a six-parametric approximation is proposed. It is found that plastic anisotropy coefficients are practically independent of deformation up to elongation of 30%. The limiting strain curve is constructed using Martsinyak - Kudzinski method relating the limiting state with a critical growth of localization of deformation under biaxial tension; to this end, an experimentally certified model of plasticity was used, as well as experimental data on limiting strains in a specimen loaded in uniaxial tension.
ON AN APPROACH TO THE DERIVATION OF CONSTITUTIVE EQUATIONS OF PHOTOCHROMIC MATERIALS
Authors: Eremeev V. A.
Published: July 2019

The paper presents constitutive equations of deformed solids, the state parameters of which, apart from the displacement vector, include concentrations of photochromic compounds. Equilibrium equations are completed with chemical kinetic equations, which are a system of, in a general case, nonlinear ordinary differential equations or parabolic-type equations accounting for the diffusion of products of photochromic reactions. Coefficients of such equations (for example, quantum reaction yield, reaction rate) can be assumed to depend on the stressed state. Several versions of the dependence of coefficients of chemical kinetic equations on the stressed-strained state are introduced. Also, in the assumption of electrostatics, possible effects of electric fields are taken into account. In analogy with mechanics of semiconductors and conductors, related equations of state are proposed.
The introduced model of a coupled photo-electro-mechanical effect is a strongly nonlinear boundary-value problem, the equations of which contain a large number of material constants that must be determined experimentally. For conducting potential mechanical experiments, a simplified one-dimensional model is proposed, which is analogous to problems of tension-compression and bending in mechanics of bars and beams. In the framework thereof, solutions of related one-dimensional problems are constructed, which make it principally possible to define dimensionless complexes containing unknown material constants.
Pergeseran Konsep Pengelolaan Ziswaf Dalam Peraturan Perundang-Undangan Di Indonesia
Authors: Fitria Maylen
Published: July 2019

Abstract
Shari'at regarding zakat, infaq, and sadaqah, is a shari'ah which shows that in Islam, not only is the relationship between humans and God important, but the relationship between humans and humans is important. In the context of legislation in Indonesia, there are two laws that deal with zakat, u 38/99 and 11/23, whose focus is the management of zakat. in both of these laws, there is no significant difference between the two rules except for the centralized management aspect of u 38 38999 and is centralized on u 23/2011. The orientation is still the same, which is to realize the hope that zakat can be one solution in realizing equity and economic justice.
Keywords: zakat law, management of zakat, purpose of zakat.
A CRISE SOCIAL NO BRASIL: BREVE REFLEXÃO E APONTAMENTOS
Authors: Santos Gabrielle Diniz , Pereira Alynete Andriola
Published: July 2019

As políticas sociais se tornaram essenciais para a garantia de direitos de uma forma mais justa para a sociedade para um todo, seja ela periférica, ou sejam elas de classes sociais com poder aquisitivo maior, sendo a primeira de maior importância por sofrer exclusões sociais. Isso decorre do histórico brasileiro de injustiças sociais, bem como de sua divisão de classes desde seu processo de colonização exploratória, em sua maioria, decorrente das colônias portuguesas. Sendo assim, este trabalho tem como objetivo discutir as práticas das políticas públicas sociais, bem como sua importância para a sociedade e como estas têm evoluído. Para a obtenção dos dados necessários para a realização do trabalho foram realizadas pesquisas bibliográficas nas plataformas de busca do Google Acadêmico e em livros relacionados ao tema. Desta forma, é possível discorrer aqui que no decorrer dos anos pós colônia, o país foi se desenvolvendo e seu crescimento econômico garantiu além de melhoria na qualidade de vida dos brasileiros, a expansão das áreas periféricas fruto do tipo de crescimento de trabalho utilizado nas indústrias e na construção civil, somado ao baixo poder aquisitivo de parcela da população, que acabaram por se dar principalmente nas grandes cidades, estas marcadas pela expansão industrial e econômica. As cidades acabaram por se tornar espaços excludentes devido essa divisão social, a qual pode ser observada com maior veemência em cidades como São Paulo e Rio de Janeiro ainda nos dias atuais. Desta forma, é possível concluir que atualmente é necessária uma reforma política, onde sejam garantidos os direitos dos cidadãos de forma mais igualitária e assim, atenuar as diferenças sociais que tanto marcam nossa sociedade.
OUTBREAK OF BOTULISM IN CATTLE IN AN AREA OF THE NORTHEAST REGION OF BRAZIL
Authors: Silva Júnior Francisco Feliciano da , Teles José Andreey Almeida , Feliciano Fábio Denilson de Oliveira , Soares Catharina de Paula Oliveira Cavalcanti , Ferreira Marcos Antônio Leal , Furtado Gil Dutra
Published: July 2019

Botulism is an intoxication caused by the ingestion of a neurotoxin produced by Clostridium botulinum, an anaerobic, Gram-positive bacteria which can sporulate in adverse conditions. This work intends to report a surge of botulism in the city of União dos Palmares, Alagoas, Brazil, which occurred in an area of milk cows with 45 animals, 14 of which had died, showing signs of weakness of the hind limbs, and in 4 cases evolved over a period of 30 days, some with profuse, brownish-green, foul-smelling diarrhea, aside from progressive weight loss. An autopsy was performed on one of the sick animals, of which no significant lesions were observed. Samples of intestinal contents were collected and centrifuged to remove supernatant and later the biological test, inoculation of mice, was performed. This test confirmed the outbreak of the disease on the property studied. Clostridium botulinum was present on the property studied, causing the outbreak of botulism. The main factor initiating the appearance of the surge was the inadequate handling of carcasses and the presence of contaminated water reservoirs. The laboratory diagnosis was of great importance in verifying a clinical suspicion.
Assessment of HER-2/neu, с-MYC and CCNE1 gene copy number variations and protein expression in endometrial carcinomas
Authors: Buchynska L.G. , Brieiev O.V. , Iurchenko N.P.
Published: July 2019

Summary. Aim: To analyze copy number variations of HER-2/neu, c-MYC and CCNE1 oncogenes and their protein expression in endometrioid endometrial carcinomas in relation to the degree of tumor progression and presence of a family history of cancer in cancer patients. Materials and Methods: The study was conducted on endometrial cancer (EC) samples from 68 patients with I–II FIGO stages of disease. Copy number analysis of HER-2/neu, c-MYC and CCNE1 genes was performed by quantitative PCR. Protein expression was analyzed using immunohistochemistry. Results: Assessment of copy number variations of HER-2/neu, c-MYC and CCNE1 genes revealed their amplification in the tumors of 18.8, 25.0 and 14.3% of EC patients, respectively. High expression of corresponding proteins was detected in 14.6, 23.5 and 65.6% of patients, respectively. It was established that HER-2/neu gene amplification is more common in the group of tumors of low differentiation grade than in moderate grade EC (35.7 and 5.5% of cases, respectively, p < 0.05). Also, high expression of c-Myc protein was more frequently observed in low differentiated tumors compared to the moderately differentiated EC (36.6 and 13.2% of cases, respectively, p < 0.05). Expression of HER-2/neu and cyclin E proteins was found to be dependent on the depth of tumor invasion into the myometrium. High expression of HER-2/neu protein was observed in 25.0 and 4.1% of EC patients with tumor invasion > ½ and < ½ of the myometrium, respectively, and cyclin E — in 86.7 and 46.6% of cases, respectively, p < 0.05. It was shown that among patients with a family history of cancer, a larger proportion of cases with high expression of c-Myc protein was observed compared to the group of patients with sporadic tumors (43.8 and 17.3%, respectively; p < 0.05). Conclusions: Amplification of HER-2/neu gene, along with high expression of c-Myc, HER-2/neu and cyclin E proteins, are associated with such indices of tumor progression as a low differentiation grade and deep myometrial invasion, suggesting the potential possibility of including these markers in the panel for determining the molecular EC subtype associated with an aggressive course of the disease. In a certain category of EC patients, there is a relationship between a family history of cancer and high expression of c-Myc protein.
THE IMPACT OF NON PERFORMING FINANCE (NPF), CAPITAL ADEQUACY RATIO (CAR), AND FINANCING DEPOSIT RATIO (FDR) TO RETURN ON ASSET (ROA) WITH DEPOSITOR FUNDS AS A MODERATING VARIABLE IN ISLAMIC BANKS
Authors: Syifa Ahmad
Published: July 2019

Return On Asset (ROA) is one of the profitability indicators, this study aimed to know the effect of several internal factors; non performing financing (NPF), capital adequacy ratio (CAR) and financing to deposit ratio (FDR) and depositors funds to Return on Asset (ROA) in Islamic commercial bank in Indonesia. This study uses a sensus method from January 2009 to December 2015. Testing the hypothesis in this study is done by using multiple linier regression test analysis and test interaction moderated regression analysis (MRA) by using Statistical Package for the Social Sciences (SPSS) 23. Result of this research hypothesis show that in the model seen a significant influence on non performing financingand capital adequacy ratio to ROA with probability value (sig-t) 0,000 lowerthan 0,05, and the value of coefficient regression are -0,349 and -0,114 with negative score, it means that if NPF or CAR increase it can make ROAdecreasing. The result of third hypothesis shows that FDR has significantinfluence to ROA with probability value (sig-t) 0,019 lower than 0,05 and the value of coefficient regression is 0,028, it means that FDR has positive influence to ROA. This study also demonstrates the role of moderating variables that can be seen from the result of fourth until sixth hypothesis testing that significantly influence to ROA with probability value (sig-t) score 0,000, 0,022 and 0,003 lower than 0,05 and have coefficient regression value equal 1,029, 0,391 and 0,073 with positive score. Statistical of F test shows that Fcal equal to 24,053 while F table at 0,846, so that F cal > F table. It means that independent variablessuch as NPF, CAR, FDR, and DPK significantly influence to Return on Asset.
THE EFFECT OF GOVERNMENT ACCOUNTING STANDARDS BASED ON AKRUAL, USING INFORMATION TECHNOLOGY, INTERNAL GOVERNMENT CONTROL SYSTEM AND ORGANIZATION COMMITMENT TO QUALITY OF CENTRAL GOVERNMENT FINANCIAL REPORT
Authors: Tiurmaida Januarti
Published: July 2019

The purpose of this study is to determine the effect of the implementation of Accounting Standards Based on Accrual Government, Utilization of Information Technology, Government Internal Control System, and Organizational Commitment to the quality of Central Government Financial Report. Central Government Financial Report is an accountability report on budget execution by Ministry / Institution. The population of research is conducted on the Ministry / Institution, with data acquisition by distributing questionnaires to the compilers of financial statements. The use of method in this research is quantitative with causal relation which is research to know influence between one independent variable (Accrual Based Government Accounting Standards, Information Technology, Government Internal Control System and Organizational Commitment) to dependent variable (Quality of Central Government Financial Report). The results of the study prove that all independent variables positively affect the quality of the Central Government Financial Statements.
THE EFFECT OF ACCOUNTING PLANT ASSETS AND LEADING COMMITMENT TO GOOD CORPORATE GOVERNANCE AND EFFECT PERFORMANCE FINANCE IN PERUM PERHUTANI HOLDING : DRAFT A PROPOSAL
Authors: Lestari Retno Martanti Endah , Farida Ida
Published: July 2019

This paper discuss about PSAK 69 agriculture with specific focus on accounting of plant assets can effect performance finance in Perhutani holding, Indonesia. Biological asset are plants and animals undergoing biological transformations. Biological transformation consists of the process of growing, developing, producing and ready quotes that lead to changes both qualitatively and quantitatively. This raises the needs of various parties regarding the ability of the aplication of PSAK 69 in biological asset, especially on the use of present value of the model of cash inflows in the future to determine the fair value of biological asset certain categories. The results of the proposed study would hopefully assist in the development of an alternative fair value model in valuing plant assets supported by leading commitment and subsequently lead to good corporate governance specifically on the performance finance.
KEEFEKTIFAN PELAKSANAAN PENANGGULANGAN BENCANA DI KABUPATEN ACEH BARAT DALAM PERSPEKTIF HUKUM BENCANA
Authors: Handoyo Budi
Published: July 2019

Article 4 of West Aceh Qanun No.13 of 2011 about Disaster Management says that the implementation of disaster management aims to provide protection to the public from the threat of disaster, aligning the legislation that already exists, ensure the implementation of disaster management in a planned, integrated, coordinated, and comprehensive, appreciate the local culture, building and public participation. However, in practice the function structure, substance and legal culture in disaster management has not been effective because it is still faced with mIany obstacles that affect the effectiveness.

                        The implementation of disaster management in Aceh Barat District have not been fully implemented yet effective considering the functioning of the three elements of the legal system became a major element of disaster management.In fact, if all three elements of a functioning legal system with another implementation of disaster management can be effective as effective as can be seen in the alignment of the substance elements Qanun No.13 of 2012 on the disaster management with other legislation.Effective functioning legal culture provide an understanding of the legal community as integration through community participation and socialization legislation implemented through institutional legal authorities.Factors which become obstacles in the disaster relief efforts in Aceh Barat District include inadequate institutional performance and disaster management officials, the low awareness of disaster risk and low understanding of both the law and public administration officials to the disaster rules
DILEMATIKA HUKUM KEDUDUKAN ANAK SEBAGAI OUTSOURCING MENURUT HUKUM KETENAGAKERJAAN
Authors: Novi Quintena Rahayu
Published: July 2019

Perlindungan anak yang bekerja masih menjadi dilema tersendiri dalam setiap daerah. Pemenuhan hak anak yang diatur dalam berbagai regulasi justru menyulitkan pemerintah untuk merealisasikan pemenuhan hak anak. Terlepas adanya larangan maupun diperbolehkannya anak bekerja menurut peraturan perundang-undangan, permasalahan paling sering terjadi dalam kaitannya dengan pemenuhan hak anak salah satunya adalah terkait bobot kerja dan pengupahan yang tidak sesuai. Kajian ini hendak mendalami permasalahan kedudukan anak sebagai outsourcing dalam hukum ketenagakerjaan dan realisasi pemerintah dalam memenuhi hak anak yang bekerja. Metode yang dalam tulisan ini adalah metode yuridis normatif dengan pendekatan preskriptif. Guna memenuhi analisa dalam kajian ini maka digunakan data sekunder, setelah data dikumpulkan maka akan dianalisa secara kualitatif.
Mining Flickr: a method for expanding the known distribution of invasive species
Authors: Allain Steven
Published: July 2019

It is important to map invasive species in order to demonstrate their rate of spread and current distribution. Most recording schemes rely on opportunistic sightings and awareness to collect and gather data. Mining data from online social media and other data sharing platforms has become more prevalent in recent years as increasing numbers of users share more information. In this study, sightings from the image sharing platform Flickr were compared with the records submitted to the national recording scheme Record Pool. This study was completed to determine whether or not there was a significant difference between these two as sources for sightings of fresh water turtles across the UK.
Effects of environmental factors and conservation measures on a sand-dune population of the natterjack toad (Epidalea calamita) in north-west England: a 31-year study
Authors:   Philip Smith
Published: July 2019

A 31-year study monitored Britain’s largest natterjack toad population on the Sefton Coast sand-dune system in north-west England. Key objectives were to describe changes in numbers and breeding success, relate these to environmental variables and explore whether conservation efforts have been well targeted. Considerable variation was found in the number of water bodies used for spawning, the number of spawn strings laid and breeding success based on estimated toadlet production. There was a declining trend in annual totals of spawn strings and toadlets. Positive correlations were established between spring and April rainfall and both spawn count and toadlet production. April rainfall for the study area declined between 2000 and 2017. Premature desiccation of water bodies and associated poor breeding success were frequently observed, there being a positive relationship between water-table height and toadlet numbers. A long-term declining trend in the height of the water-table was established. The mean adult population of Sefton natterjacks was estimated at about 1200 individuals, with a peak around 3150. Successful breeding is increasingly reliant on management to excavate appropriately designed and managed “scrapes” that hold water long enough for metamorphosis to occur. Overgrowth of vegetation and loss of dynamism in the dune system threaten both the natural production of new breeding slacks and the natterjack’s open terrestrial habitat. Encouragement of dune dynamics by removing trees and scrub, increasing areas subject to livestock grazing and mechanical rejuvenation may offer the best hope of conserving this species in the future.
Dealing with hot rocky environments: Critical thermal maxima and locomotor performance in Leptodactylus lithonaetes (Anura: Leptodactylidae)
Authors: Beltran Ivan
Published: July 2019

Environmental temperature has fitness consequences on ectotherm development, ecology and behaviour. Amphibians are especially vulnerable because thermoregulation often trades with appropriate water balance. Although substantial research has evaluated the effect of temperature in amphibian locomotion and physiological limits, there is little information about amphibians living under extreme temperature conditions. Leptodactylus lithonaetes is a frog allegedly specialised to forage and breed on dark granitic outcrops and associated puddles, which reach environmental temperatures well above 40 ˚C. Adults can select thermally favourable microhabitats during the day while tadpoles are constrained to rock puddles and associated temperature fluctuations; we thus established microhabitat temperatures and tested whether the critical thermal maximum (CTmax) of L. lithonaetes is higher in tadpoles compared to adults. In addition, we evaluated the effect of water temperature on locomotor performance of tadpoles. Contrary to our expectations, puddle temperatures were comparable and even lower than those temperatures measured in the microhabitats used by adults in the daytime. Nonetheless, the CTmax was 42.3 ˚C for tadpoles and 39.7 ˚C for adults. Regarding locomotor performance, maximum speed and maximum distance travelled by tadpoles peaked around 34 ˚C, approximately 1 ˚C below the maximum puddle temperatures registered in the puddles. In conclusion, L. lithonaetes tadpoles have a higher CTmax compared to adults, suggesting a longer exposure to extreme temperatures that lead to maintain their physiological performance at high temperatures. We suggest that these conditions are adaptations to face the strong selection forces driven by this granitic habitat.
Phylogenetic relationships and origin of the rattlesnakes of the Gulf of California islands (Viperidae: Crotalinae: Crotalus)
Authors:   Francisco Javier Garcia-de Leon
Published: July 2019

The islands of the Gulf of California are divided into three categories – oceanic, continental, and landbridge – and were formed from the Middle Miocene to the Holocene. The species of the Crotalus genus are an important ecological element of the endemic fauna of these islands. This study is the first to include several island-endemic species in a phylogenetic framework. We seek to understand the phylogenetic relationships among these species, and in particular, whether these species are more related to the Baja California peninsula or continental Mexican species, and whether the divergence times for these relationships are consistent with the formation of the islands. We performed a phylogenetic analysis and estimated divergence times using Bayesian inference and two mitochondrial 12S and 16S genes. The analyses show a new relationship between Crotalus angelensis and C. pyrrhus. Crotalus lorenzoensis was nested with C. ruber individuals, making this species a
paraphyletic species. A novel relationship was also detected in that C. estebanensis was sister to C. basiliscus. The divergence time for all island-endemic Crotalus species is consistent with the formation of these islands. In addition, the insular species are related to their congeners in the Baja California peninsula or mainland Mexico.
Observations of threatened Asian box turtles (Cuora spp.)
on trade in Vietnam
Authors:   Luca Luiselli
Published: July 2019

Asian box turtles (genus Cuora; Geoemydidae) are among the most threatened Asian turtles. Here, we present (i) a field investigation from 2014-2018 on the Cuora individuals traded by high-level traders in six provinces of Vietnam and (ii) the estimated numbers of traded individuals determined through interviews with traders. In addition, we (iii) provide an analysis of the confiscated individuals that were carried out at the main wildlife rescue centre of the Socialist Republic of Vietnam. Overall, the number of traded individuals observed was relatively small (n = 481), with C. bourreti being by far the most frequently observed in trade. During the same period, the interviewed traders estimated that about 3,400 individuals
were traded through the period 2014-2018, most of them being C. bourreti. During 2010-2018, a total of 281 individuals were carried to the wildlife rescue centre, with over 60 % of the total rescued individuals being C. galbinifrons. Overall, the numbers of traded Cuora individuals recorded in the present study were very small compared to the huge estimates from
other Asian countries. However, this lower traded number does not imply that the status’ of the target species are not affected, as their population sizes are already catastrophically reduced in Vietnam.
Estrategias para el desarrollo sostenible y sustentable del Geoparque Imbabura, Ecuador.
Authors: La Serna Gómez Adelfa María , Rhea González Bertha Soraya , Vasallo Villalonga Yoarnelys
Published: July 2019

El objetivo de la investigación es realizar una propuesta de estrategias para el desarrollo sostenible y sustentable del Geoparque Imbabura, ubicado en la provincia del mismo nombre en la sierra norte ecuatoriana, y actualmente en fase de solicitud a la UNESCO. Los métodos utilizados fueron el histórico-lógico, inductivo-deductivo y el analítico - sintético para la revisión de documentos que establecen las estrategias vigentes en la zona. Asimismo, como elemento empírico, se consultó el criterio de expertos en estrategias para el desarrollo local, y se realizó el estudio comparativo de metodologías empleadas en investigaciones precedentes. Los resultados parciales de la investigación responden a los objetivos propuestos. Se comprobó el potencial que representa el desarrollo turístico para la puesta en valor del patrimonio natural, la necesidad de conciliar las estrategias existentes y de enfocar nuevas para la mayor incorporación de los sectores sociales implicados en los cambios económicos, la sostenibilidad y sustentabilidad del Geoparque.
Health-related quality of life following heart surgery
Authors: Ranjan Redoy , Adhikary Dipannita , Saha Sanjoy Kumar , Adhikary Asit Baran
Published: July 2019

This study evaluates the differences in preoperative and postoperative health-related quality of life of the patients following heart surgery and observed the factors that influence quality of life changes. This prospective observational study involved two parameters from the SF-36 questionnaire before and one year after heart surgery in a single surgeon’s practice. At the baseline assessment of the study observed 140 patients, predominantly were male in both study groups. The mean age was 56.8 ± 4.2 years, 64.7 ± 7.4 years in Group of patients age ≤ 60 years and age >60 year’s respectively. In elderly aged group, patients have greater risk of co-morbidity, operative complications, and low preoperative as well as postoperative quality of life score. There was an overall improvement in all majority health domains of the SF-36 questionnaire among study population. Statistical results from Logistic multivariate analysis demonstrates a greater value of preoperative mental component summary scores (p=0.08), and physical component summary scores (p=0.01) as potential risk factors for non-improvement following heart surgery. Although, elderly patients (age >60 year’s) with greater operative risk have low preoperative quality of life score, but demonstrate an equal improvement in most of the health domains following heart surgery as like as younger study population.
Nanohybrid and microfilled composite resin in Class II restoration of permanent molar teeth
Authors: Ali Hasan , Abdin Md. Joynal , Akhter Noor Jahan , Hossain Mozammal
Published: July 2019

The aim of this study was to compare the clinical performance of nanohybrid composite resin in Class II restorations placed with a one-step self-etch adhesive with that of microfilled composite resin of permanent posterior molar teeth. A total of 100 participants who received Class II restorations either with nanohybrid composite resin bonded with a single step self-etch adhesive or conventional microfilled composite bonded with a single step self-etch adhesive. All restorations were evaluated by using slightly modified USPHS criteria at baseline and after 3, 6 and 12 months. The results revealed that nanohybrid composite resin showed better clinical outcome than that of the conventional microfilled composite resin restorations in respect to retention and marginal adaptation at 12 months observation period. It can be concluded that nanohybrid is superior to conventional microfilled composite resin in respect to retention, and marginal adaptation of Class II restorations of permanent molar teeth.