bluuebunny/crossref_metadata_2025 huggingface dataset:
Adaptación de sistemas naturales y sociales al cambio climático en el Ecuador: una revisión
Authors: Jiménez Torres Alexandra del Cisne , Castillo-Acaro Estefanía , Jiménez-Jiménez Lorena , Pucha-Cofrep Darwin
Published: July 2022

En los últimos años el cambio climático se ha convertido en un problema grave en ascenso, que ha llamado la atención de la comunidad científica y preocupación de gobiernos, cuyo reto principal es adoptar medidas que ayuden a reducir los impactos. Este artículo presenta una revisión bibliométrica de investigaciones en español realizadas durante el periodo 1991-2021 donde se analizaron los sitios estudio, metodologías, técnicas, la percepción de cambio de las variables climáticas, enfoques y estrategias de adaptación. Este estudio busca mostrar más información actual sobre la adaptación de los sistemas naturales y humanos al cambio climático en Ecuador. Para ello, se definieron criterios de selección, recuperación y evaluación de publicaciones. Los resultados revelaron que la investigación sobre la adaptación al cambio climático en Ecuador se incrementó durante el período 2011-2021, especialmente en la región Sierra. Las metodologías mixtas fueron las más utilizadas en este tipo de estudios, adicionalmente, los principales hallazgos evidenciaron que la población ecuatoriana percibe cambios de aumento, disminución y comportamiento variado de la precipitación, temperatura, y vientos. Finalmente, se evidenció que, para los impactos sobre los sistemas naturales y humanos, se han implementado estrategias en territorio bajo diferentes enfoques de adaptación, particularmente basado en comunidades humanas y ecosistemas.
Loja, referente en la conservación ecológica y cuidado ambiental nacional en Ecuador
Authors: Aguirre Mendoza Zhofre Huberto , Contento Cristian , Aguirre Luis
Published: July 2022

Conservar los recursos naturales es una tarea compleja, requiere la participación activa de la población. En la ciudad y provincia de Loja, gran parte de sus habitantes han entendido este aspecto, con cambios significativos en su cultura ecológica y ambiental. Este artículo tiene el propósito de analizar y sistematizar algunas experiencias y acciones ecológicas y ambientales desarrolladas en la ciudad y provincia de Loja, su impacto en la cultura ambiental de los lojanos y sus perspectivas futuras. Se revisó información secundaria de tesis de grado, reportajes periodísticos y observaciones de los autores en relacionados al manejo de la  ecológico y ambiental. Existen resultados y experiencias muy interesantes, así se puede mencionar: funcionamiento de la primera central hidroeléctrica del Ecuador, utilización de energía eólica y solar, manejo de los desechos sólidos, consolidación de parques y senderos  públicos para la interpretación y educación ambiental (Plan del Sistema Verde Urbano de Loja), proyectos de investigación y conservación impulsados por la academia y reconocimientos internacionales. De esta manera, Loja se ha convertido en el referente nacional e internacional en este campo, demostrando que es posible una transición progresiva hacia una cultura ecológica y sustentable, con la participación activa de los actores sociales.
The proportion of the divisor by the multiple In the Holy Quran from Surat Al-Saffat to Al-Adiyat
Authors: Alsaedy Monifah
Published: July 2022

The Qur’an is miraculous, and its miracle has many aspects, including the rhetorical miracle, which among its forms is the oath method, as the harmony of its pillars with each other is evidence and evidence of the greatness and consistency of the Qur’an. In addition to the problems that appeared about the oath, some called for an added, omitted appreciation, which is the name of God Almighty before the division of creatures to get out of this problem. So: Consider choosing one of the traits of the divider rather than others, which leads to the consistency of the systems in its best form. The significance of this research: It is to highlight the aspects of proportionality between the divisor with the multiple, whether the descriptions are united or different, and to reveal the reason for choosing one of the characteristics of the divider without others. The subject of the study in this research: mentioning the sayings of the scholars regarding the divide by it and highlighting the aspects of proportionality between them. The multiple divisions have been presented in it in twenty-one places, all of which are in the last quarter of the Qur’an. The subject of the study in this research: mentioning the sayings of scholars regarding the divide by it and highlighting the aspects of proportionality between them. I have concluded from the research with a set of results, including: that the attention to mentioning the proportionality between the divisor, although it appeared late, but its roots are rooted since the era o f the righteous ancestors, may God be pleased with them, and this shows: through their sayings in the interpretation of what is meant by the sworn, And taking into account that relationship, and one of the recommendations of the research: Draw the attention of researchers to the fact that the method of oath in the Noble Qur’an still contains a remnant of who willing.
Determinants of readability of financial statements in Kenya
Authors: N Ndegwa James
Published: July 2022

The current study set out to investigate the determinants of readability of financial statements of Kenyan-listed firms. A deductive approach was employed and data was collected from a sample of 59 companies listed in the NSE in a census study over 5 years between years 2014 to 2018.  Prais Winsten regression model was employed and the findings indicated that file size had a significant and negative effect on the readability of financial statements in Kenyan listed firms. The implication is that large-size financial statements are more difficult to read than smaller ones. This finding is consistent with reality since it will take less time to read small-sized financial statements than larger ones. Preparers of financial statements who are the firm managers should thus be careful about this finding. Regulatory authorities should develop policies that encourage the production of smaller volume financial statements to enhance their readability by the end-users. The current study is the first in East Africa since there has been no study on the readability of financial statements that have employed readability indices and that has regressed determinants against the readability of financial statements in this region.
An Analysis on Irony in Pride and Prejudice from the Perspective of Speech Act Theory
Authors: SUN YAJIE
Published: July 2022

Pride and Prejudice, as Jane Austen’s most representative novel, has high literary value and research significance.

The most notable feature of this novel is irony, which is employed to depict character images and highlight psychological activities and relationships among the characters. Irony is closely related to speech act theory, this article in the framework of speech act theory analyzes irony form the macro and micro perspective, thus proves the feasibility of application of theory of general linguistics to the analysis of fiction texts.
Research Review on Accessibility and Equalization of Public Cultural Services in Chinese Rural Areas
Authors: Zhang Juan , Wang Bo
Published: July 2022

Geographers have conducted a lot of research on the accessibility of public service facilities and the equalization of public services based on the perspective of human-land relationship. The common feature is to analyze the accessibility and equalization of a specific type of public service facilities, to understand the current spatial pattern of service facilities, to evaluate the spatial balance of facility distribution, to identify the scarcity areas of facility supply, and to optimize the overall deployment pattern by selecting sites for new facilities with other measurement methods. In terms of research area, there are more large-scale spatial accessibility studies in favor of urban areas, but few studies specifically focus on accessibility in rural areas; there is also a lack of research on the spatial pattern of equalization based on the rural perspective. From the perspective of public service facility types, medical and education are the main research objects, while cultural service facilities are less involved. Therefore, research on the spatial accessibility and equalization of public service facilities should be extended more to cultural facilities, especially the spatial equity of public cultural service facilities in rural areas. The focus should be on how to visually express the layout of public cultural services as well as comprehensively consider factors such as the location of rural settlements, distance to facility sites, transportation networks, travel modes, and choice preferences. It is suggested to introduce the analysis of multiple quantitative indicators of accessibility into the planning and construction of public service facilities to further strengthen the realism and scientificity of public service facility planning. Reasonable site selection and optimization of layout patterns for public cultural facilities is also a key factor to improve the construction of basic public service system in rural areas.
Crossing, Leaping and Transcendence：Analysis of Pakistani Film and TV dramas Released in China
Authors: Jun
Published: July 2022

Abstract: The friendship between Pakistan-China is deeply rooted in the hearts of people of the two countries. The exchanges and mutual learning through the film, television and drama playeda  significance role to strengthen the bond among the people of both countries. Since the establishment of diplomatic ties between the two countries, the exchange of film and television products have gone through ups and downs, and the dissemination of Pakistani film and television products have also experienced twists and turns. In 2020, the Pakistani film " Parwaaz Hai Junoon " was released in China, which aroused some response and gave impetus to cultural exchanges. It also open doors for Pakistani films and drama in China. Despite the improvement of the quantity and quality of Pakistani film and television products, these could not spread in China mainland at greater extent, with the advent of the era of "mixed war", the conflict of values has become a problem that should be addressed in film and television communication. The bilateral political trust, ideological security demand at present, ask for promotion of cross-cultural communication through film and television products. There should be mechanisms, which can help to overcome obstacles actively, expand new path, clever use of all kinds of social and short video platform.  Pakistani film in China should also ensure communication quality at all level and at the same time boost the cooperation between two countries field of film and television products. The in-depth exchanges and high-level mutual learning in the fields of film and television between China and Pakistan are worth looking forward to.
Three key genes expression profiling in Egyptian rheumatoid arthritis patients
Authors:   Department of Physical Medicine, Rheumatology & Rehabilitation, Faculty of Medicine, Suez Canal University, Ismailia, Egypt., Abdelnaby Mai , Badran Dahlia ,   Department of Medical Biochemistry & Molecular Biology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt., Anani Maha ,   Department of Clinical Pathology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt., Hashem Asmaa ,   Department of Medical Microbiology & Immunology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt., Moneim Nermeen ,   Department of Physical Medicine, Rheumatology & Rehabilitation, Faculty of Medicine, Suez Canal University, Ismailia, Egypt., Eldesouki Raghda ,   Medical Genetics Unit, Department of Histology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt., Elmedany Samah ,   Department of Physical Medicine, Rheumatology & Rehabilitation, Faculty of Medicine, Tanta University, Tanta, Egypt., Hosny Marwa ,   Department of Medical Biochemistry & Molecular Biology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.,   Oncology Diagnostic Unit lab, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.
Published: July 2022

Rheumatoid arthritis (RA) is a multi-system autoimmune disease with synovial joints involvement. The triad of autoimmunity, genetics, and environment is the key player in RA pathogenesis. We intended to investigate gene expression of C-C Chemokine Ligand 2 (CCL2), protein tyrosine phosphatase non-receptor type 22 (PTPN22), and Cytotoxic T-lymphocyte associated protein 4 (CTLA-4) in RA patients versus controls, and its correlation with the activity of the disease. The relative expression of PTPN22, CTLA-4, and CCL2 in the peripheral blood of 59 RA patients and 50 controls was determined using RT-PCR. There was a significantly higher median (inter-quartile range) expression of CTLA-4 and CCL2 in RA patients in comparison to controls (P<0.05). However, in RA patients, PTPN22 expression was significantly lower than in controls (P=0.0001). A weak significant correlation was detected between PTPN22 and either CTLA-4 or CCL2. Also, on comparing RA patients with moderate to severe disease activity versus those who have a mild disease activity, CCL2 was significantly over-expressed (P > 0.05). Thus, in Egyptian RA patients, there was a significant PTPN22 down-expression and greater expression of CTLA-4 and CCL2. Moreover, over-expression of CCL2 in RA patients with moderate-to-severe disease activity was significant. We conclude that these three key genes could become useful diagnostic markers for RA and CCL2 expression as a good prognostic tool for RA disease activity.
Neutralizing antibody responses in asymptomatic close contacts of COVID-19 patients and in asymptomatic healthcare workers
Authors:   Department of Clinical Pathology, Faculty of Medicine, Assiut University, Assiut, Egypt., Mahmoud Amal , Hussein Aliae ,   Department of Pulmonology, Assiut University, Assiut, Egypt., Makhlouf Nahed ,   Department of Tropical Medicine & Gastroenterology, Faculty of Medicine, Assiut University, Assiut, Egypt., Makhlouf Hoda ,   Department of Pulmonology, Assiut University, Assiut, Egypt., Yassa Heba ,   Forensic Medicine and Clinical Toxicology, Faculty of Medicine, Assiut University, Assiut, Egypt., EzzEldi Azza , Abdel Aal Amal ,   Department of Clinical Pathology, Faculty of Medicine, Assiut University, Assiut, Egypt.
Published: July 2022

The identification of novel antibodies that could neutralize SARS-CoV-2 is one of the novel approaches to use in combating COVID-19. This study aimed to explore the level of neutralizing antibodies (NAbs) in asymptomatic close contacts of COVID-19 patients and asymptomatic healthcare workers. In vitro qualitative detection of serum antibodies of participants from both populations was done using an anti-SARS-CoV-2 immunoassay. The study included 107 participants, of which 59.8% were healthcare workers and 40.2% were family contacts of confirmed COVID-19 cases. Their median age was 22 years. The percentage of positivity and median titer for NAbs were significantly higher among family contacts than mong healthcare workers (P = 0.013 and <0.001, respectively). We also measured C-reactive protein (CRP) levels and the median value of CRP was significantly higher in the family members who had been in contact with COVID-19 patients than in healthcare workers (P < 0.001). In the family contact group, there was a significant negative correlation between the absolute lymphocyte count and CRP (r = −0.409, P = 0.034). There was no significant correlation between neutralizing antibody titers and either CRP or absolute lymphocyte count (P > 0.05 for both). In conclusion, the indication of elevated NAb titers in asymptomatic family contacts could help lay the groundwork for further studies to explore the potential utility of these antibodies to provide future immunity from infection within a family as well as for potential use in general during passive antibody therapies for COVID-19 patients.
Disheveled EGL-10 and pleckstrin domain-containing 5 rs1012068 T/G gene polymorphism among Egyptian chronic HCV-infected patients: disease progression and related complications
Authors:   Department of Clinical & Chemical Pathology, Faculty of Medicine, Beni-Suef University, Beni-Suef, Egypt., Farhan Hanan , Abougabal Khadiga ,   Department of Clinical & Chemical Pathology, Faculty of Medicine, Beni-Suef University, Beni-Suef, Egypt., Gaber Heba ,   Department of Clinical & Chemical Pathology, Faculty of Medicine, Beni-Suef University, Beni-Suef, Egypt., Attia Dina ,   Department of Tropical Medicine, Faculty of Medicine, Beni-Suef University, Beni-Suef, Egypt.
Published: July 2022

Hepatitis C virus (HCV) infection related complications including fibrosis, cirrhosis and hepatocellular carcinoma (HCC) are influenced by host genetic factors. Identification of emerging host genetic variations is of promising value. Disheveled EGL-10 and pleckstrin domain-containing 5 (DEPDC5) rs1012068 T/G gene polymorphism has been implicated in liver disease. This study aimed to assess DEPDC5 rs1012068 T/G gene polymorphism with disease progression and related complications among Egyptian patients with chronic HCV infection. Sixty chronic HCV-infected patients and 60 apparently healthy controls were recruited in this study. Patients were classified into 20 with liver fibrosis, 20 with liver cirrhosis and 20 with HCC; all recruited from Outpatients Clinic and Tropical Medicine Inpatient Department, Faculty of Medicine, Beni-Suef University Hospital. DEPDC5 rs1012068 T/G gene polymorphism was assayed by real time-polymerase chain reaction (RT-PCR) TaqMan allelic discrimination. DEPDC5 rs1012068 GG genotype and G allele variants showed statistically significant higher frequency among patients with liver fibrosis when compared to controls (OR (95% CI) 10.500 (2.086 – 52.851), P= 0.004 and 0.388 (0.155 – 0.971), P= 0.011), respectively. DEPDC5 rs1012068G allele variant showed statistically significant higher frequency among patients with liver fibrosis when compared to HCC patients (OR (95% CI) 3.316 (1.286 – 8.550), P= 0.012) and to both HCC and cirrhosis patients (OR (95% CI) 2.579 (1.187-5.645), P= 0.016). In conclusion, our results suggest that DEPDC5 rs1012068 G allele could be considered genetic risk allele for liver fibrosis and disease progression among Egyptian patients with chronic HCV infection.
Inetrleukin-6 and C-reactive protein as predictors of mortality among critically ill COVID-19 patients in Assiut university hospitals (ICUs)
Authors:   Department of Clinical Pathology, Faculty of Medicine, Assiut University, Assiut, Egypt., Ahmed Asmaa , Rashed Hebat Allah ,   Department of Clinical Pathology, Faculty of Medicine, Assiut University, Assiut, Egypt., Solyman Alshymaa ,   Department of Clinical Pathology, Faculty of Medicine, Assiut University, Assiut, Egypt., Abd El-Kareem Doaa ,   Department of Clinical Pathology, Faculty of Medicine, Assiut University, Assiut, Egypt.
Published: July 2022

COVID-19 represents a serious global threat due to scarcity of definitive cure and its infectious nature. The death rate of COVID-19 patients admitted to hospitals was quite high, and cytokine storms could be the mechanism of severity. Interleukin-6 (IL6) and C-reactive protein (CRP) may predict severity and mortality. We attempted to determine the role of IL6 and CRP as predictors of death in intensive care unit (ICU) patients. This Cross-sectional hospital study included 100 patients admitted to ICUs at Assiut University Hospitals from October 2020 to October 2021. Data including age, sex and comorbidities were recorded, laboratory investigations included CRP, ferritin, and IL6. Data were collected and analyzed. Morality predictors in ICU patients with COVID-19 infection were older age (>60 years), presence of diabetes mellitus, chest diseases, CRP >49, IL-6 >70 pg/ml. In conclusion, early ranking and identification of people, who are at risk of death among ICU patients, by monitoring of CRP, IL6, early treatment of cytokine storm, and good management of pre-existing comorbidities would be a very useful approach to reduce the mortality among ICU patients.
Angiogenic activities of interleukin-8, vascular endothelial growth factor and matrix metalloproteinase-9 in breast cancer
Authors:   Department of Immunology & Allergy, Medical Research Institute, Alexandria University, Alexandria, Egypt., Abou Shousha Seham , Hussein Basma ,   Department of Immunology & Allergy, Medical Research Institute, Alexandria University, Alexandria, Egypt., Shahine Yasmine ,   Department of Microbiology & Immunology, Faculty of Pharmacy, Pharos University, Alexandria, Egypt., Fadali Geylan ,   Department of Pathology, Medical Research Institute, Alexandria University, Egypt., Zohir Malak ,   Department of Pathology, Medical Research Institute, Alexandria University, Egypt., Hamed Yasser ,   Department of Experimental and Clinical Surgery, Medical Research Institute, Alexandria University, Alexandria, Egypt., Baheeg Suzan ,   National Institute of Oceanography and Fisheries, Central Laboratories Unit, Alexandria Egypt, Ibrahim Ahmed ,   Department of Immunology & Allergy, Medical Research Institute, Alexandria University, Alexandria, Egypt., El Shannawy Mohammed ,   Department of Immunology & Allergy, Medical Research Institute, Alexandria University, Alexandria, Egypt., Osman Eman ,   Department of Immunology & Allergy, Medical Research Institute, Alexandria University, Alexandria, Egypt.
Published: July 2022

Angiogenesis is a major contributor to tumor growth and metastasis within breast cancer tumor microenvironment in which different proangiogenic factors have been identified and associated with tumor progression, metastasis and poor prognosis. The aim of the current study was to evaluate the angiogenesis among breast cancer patients through ex vivo assessment of the angiogenic factors interleukin 8 (IL-8) and vascular endothelial growth factor (VEGF)-A expressions in excised tumor tissues as well as matrix metalloproteinase 9 (MMP-9) serum levels as well as the prognostic value of MMP-9. Our study included 28 invasive ductal carcinoma female patients who were scheduled for modified radical mastectomy at Medical Research Institute, Alexandria University, Egypt and 10 control subjects. Both IL-8 and VEGF-A expressions were immunohistochemically detected in tumor tissues and serum MMP-9 was determined by ELISA. Although no significant correlations were found between each of IL-8, VEGF-A, MMP-9 levels, and patients’ clinicopathological parameters, a significant positive correlation was found between these angiogenic factors each other suggesting their synergistic roles in proceeding angiogenesis. Higher serum MMP-9 level was detected in breast cancer patients compared to the control group, indicating that it can be used as a prognostic biomarker in breast cancer patients.
Maternal serum perlecan and ischemia modified albumin levels as biomarkers of preeclampsia severity
Authors:   Department of Clinical Pathology, Faculty of Medicine for Girls, Al- Azhar University, Cairo, Egypt., Mokhtar Entsar , Abd El-hakam Faiza ,   Department of Obstetric & Gynecology, Faculty of Medicine for Girls, Al- Azhar University, Cairo, Egypt., Ebriheem Eman ,   Department of Medical Biochemistry, Faculty of Medicine for Girls, Al- Azhar University, Cairo, Egypt., El Attar Shahinaz ,   Department of Medical Biochemistry, Faculty of Medicine for Girls, Al- Azhar University, Cairo, Egypt., Hassan Marwa ,   Department of Internal Medicine, Faculty of Medicine for Girls, Al- Azhar University, Cairo, Egypt., Al Anany Mona ,   Department of Physiology, Faculty of Medicine for Girls, Al- Azhar University, Cairo, Egypt.
Published: July 2022

Preeclampsia (PE) is a pregnancy disorder characterized by hypertension and end-organ damage. Reliable biochemical markers for diagnosis and prediction of PE severity can improve maternal health, and several of these markers have been suggested till now. The goal of our study was to evaluate maternal serum levels of Perlecan and Ischemia modified albumin (IMA) in PE patients, and to investigate their relationship with the severity. This study included 45 pregnant women, who were divided into three groups: mild PE (n=15), severe PE (n=10), and normal pregnant females (n=20) as a control group. Maternal serum levels of Perlecan and IMA were determined by the enzyme linked immunosorbent assay (ELISA). Preeclamptic women with severe features have significantly higher serum Perlecan and IMA levels than women with mild PE and control (P<0.001 for both). Serum levels of Perlecan and IMA were significantly increased in patients with mild PE as compared with control (P<0.001 for both). Serum Perlecan levels were positively correlated with systolic blood pressure (SBP), diastolic blood pressure (DBP), ALT, AST, creatinine, urea, uric acid, and proteinuria, but negatively correlated with platelet count and fetal birth weight. Serum IMA level was positively correlated with SBP, DBP, but negatively correlated with Albumin, and fetal birth weight. The receiver operating characteristic (ROC) curve analysis was performed to evaluate the diagnostic performance of Perlecan and IMA in the prediction of PE severity. Serum Perlecan had greater sensitivity and lower specificity for severe PE than for mild PE. Serum IMA had greater sensitivity and lower specificity for severe PE than for mild PE. In conclusion, maternal serum Perlecan and IMA levels were biomarkers for monitoring PE and the increase in serum Perlecan levels was in accordance with the severity of PE. Also, Perlecan was superior to IMA as a predictor for PE severity.
Neutrophil Respiratory Burst: an immunological indicator of post stroke infection
Authors:   Department of Internal Medicine, Allergy & Clinical Immunology, Faculty of Medicine, Ain Shams University, Cairo, Egypt., Okba Ashraf , Farres Mohamed ,   Department of Internal Medicine, Allergy & Clinical Immunology, Faculty of Medicine, Ain Shams University, Cairo, Egypt., Shahin Rasha ,   Department of Internal Medicine, Allergy & Clinical Immunology, Faculty of Medicine, Ain Shams University, Cairo, Egypt., Mostafa Asmaa ,   Department of Internal Medicine, Allergy & Clinical Immunology, Faculty of Medicine, Ain Shams University, Cairo, Egypt., Elkady Hossam ,   Department of Internal Medicine, Allergy & Clinical Immunology, Faculty of Medicine, Ain Shams University, Cairo, Egypt., Sheha Dina ,   Department of Internal Medicine, Allergy & Clinical Immunology, Faculty of Medicine, Ain Shams University, Cairo, Egypt., Hossam Afify ,   Department of Neurology, Faculty of Medicine, Ain Shams University, Cairo, Egypt., Sheha Aliaa ,   Department of Radiodiagnosis, Faculty of Medicine, Ain Shams University, Cairo, Egypt., Rushdy Marwa ,   Department of Clinical Pathology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Published: July 2022

Stroke is long known to be followed by a series of immunosuppressive events, and infections might be a cause of death after an acute insult of stroke. The aim of our work was to assess the percentage of neutrophils showing spontaneous oxidative burst in patients with acute ischemic stroke. The study included 30 patients with acute cerebral infarction subjected to the following: magnetic resonance imaging of the brain immediately on admission, and blood sampling on day one of admission (baseline) and after 3 days of admission. Blood samples were used for the assessment of: differential leucocyte count and percentage of neutrophils showing spontaneous oxidative burst, performed by flow cytometry. Thirty age and gender matched controls were also recruited. Neutrophil respiratory burst percentage was significantly lower in stroke patients in comparison to controls (P<0.001), and stroke patients had significantly lower neutrophil respiratory burst percent on day 3 of admission compared to the baseline (P<0.001). Stroke-induced immune alterations including impairment of the first-line defense performed by neutrophils against bacteria. The hypothesis that these changes enhance susceptibility to acquired infections is supported by our observation that oxidative burst in neutrophils was more impaired in patients with stroke who exhibited subsequent stroke-associated infections.
IL-17A )rs2275913; G197A) gene polymorphism as predictor for disease severity and its correlation with IL-17 serum levels in COVID-19 patients
Authors:   Department of Clinical Pathology, Faculty of Medicine, Ain Shams University, Cairo, Egypt., Rushdy Marwa , Elsayed Marwa ,   Department of Medical Microbiology & Immunology, Faculty of Medicine, Ain Shams University, Cairo, Egypt., Ahmed Rasha ,   Department of Geriatric & Gerontology, Faculty of Medicine, Ain Shams University, Cairo, Egypt., Gaber Amr ,   Department of Anesthesia, ICU, & Pain Management, Faculty of Medicine, Ain Shams University, Cairo, Egypt., El-Asady Riham ,   Department of Medical Microbiology & Immunology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Published: July 2022

Severity of symptoms in COVID-19 has been shown to result from a cytokine storm. Interleukin (IL)-17 is one of these various cytokines, which results in a proinflammatory response, systemic inflammatory symptoms, inflammatory cell infiltration of lung tissue and thus leads to the massive lung pathology and multiorgan failure. Gene polymorphisms in the regulatory regions of cytokine-encoding genes affect the amounts of cytokines produced and possess a fundamental role in infectious diseases. This study aimed to investigate the role of IL-17A (rs2275913; G197A) gene polymorphism as predictor of disease severity and its correlation with IL-17 serum levels in COVID-19 patients. A group of 70 COVID-19 patients and 17 age and sex-matched control subjects were enrolled in the present work. Patients were classified into two groups moderate, severe and acute respiratory distress (ARDS) cases, defined according to the criteria established by the world health organization. Quantitative real time-polymerase chain reaction was done to detect IL-17A (rs2275913; G197A). Serum IL-17 levels were assessed by an enzyme-linked immunosorbent assay in both patients and controls. The distribution of different IL-17A G/A genotypes among COVID-19 patients were 44.3% for GG genotype, 44.3% for AG genotype and 11.4% for AA genotype. Genotypes among the control group were 43.8% for GG genotype, 50% for AG genotype and 6.3% for AA genotype. G allele distribution was 66.4%, 68.8% in patient and control group, respectively, and A allele was 33.6% and 31.3%, respectively. There was no association between the different genotypes, disease severity or IL-17 serum levels in the patient group. In conclusion, despite the possible role of IL-17 in the pathogenesis of inflammation, there was no association between IL-17 polymorphism and disease severity or IL-17 serum levels among Egyptian COVID-19 patients.
A Value Co-Creation Perspective on Faculty Staffing
Authors: Pavlov Oleg V. , Lofgren Joan , Hoy Frank
Published: July 2022

Colleges and universities increasingly employ temporary instructors. Researchers in higher education have voiced strong concerns about this trend because of its impact on educational outcomes, operations of academic institutions, and the composition of academic workforce. To enhance our understanding of this employment practice, this article makes three contributions to the research on the growing non-tenured employment in academia. First, we advance the theory by arguing that the value co-creation framework, also referred to as service science, is an appropriate theoretical lens for studying higher education, including faculty employment. Second, we use this framework to analyze operations of a selective undergraduate program in Finland that has been functioning for over 30 years without permanent teaching faculty. Housed at a premier business school, the program relies on an expansive international network of instructors who travel to teach on short-term contracts. Third, we demonstrate that the staffing model used by this Finnish program is distinct from other forms of temporary academic employment, and therefore we label it a networked faculty staffing model. To the best of our knowledge, this is the first time the value co-creation framework is used as a theoretical lens to study employment in higher education. Moreover, this is the first time a networked faculty staffing model is explicitly identified and described. Besides researchers, this article might be of interest to the diverse international audience who are involved in management and policy setting in higher education.
Forecasting Oil Prices: A Comparative Study
Authors: Hokayem Jihad El , Gemayel Joseph , Mezher Dany
Published: July 2022

Oil prices have been a major concern for many policy makers, businesses and individuals throughout the years. The spillover of inflation, which is at its highest level since several decades, due to the supply chain problems and spike in energy prices, following the war between Russia and Ukraine pushed oil and gas under the spotlight recognizing its crucial role. In turn, this has imposed many challenges on numerous countries across regions building up feelings of fear and anxiety amid serious concerns about energy and food security. Forecasting oil prices is still a major challenge as it is stimulated by various influencers. With the availability of numerous techniques to forecast oil prices, this study aims to compare the Vector Autoregression (VAR), Autoregressive Conditional Heteroskedasticity (ARCH) and Generalized Autoregressive Conditional Heteroskedasticity (GARCH) models in forecasting oil prices.
Penyewaan Hewan Pejantan Kambing Dalam Perspektif Kompilasi Hukum Ekonomi Syariah
Authors: Badrun
Published: July 2022

Ijarah termasuk perpindahan barang atau jasa dengan persewaan melalui pemiliknya. Di Kampung Banjar Negara dalam pelaksanaannya masyarakat biasanya menggunakan dua tahapan yaitu akad sewa dan akad meminjam didalam pelaksanaan sewa-menyewa nampak adanya unsur yang ketidak pastian hasil perkawinan yang belum bisa dipastikan hasilnya. sedangkan dalam penyewaan kambing pejantan yang diambil adalah air mani kambing. Hal ini menjadi permasalahan bagaimaan penyewaan hewan pejantan kambing di Kampung Banjar Negara Kec. Baradatu Kab. Way Kanan dalam perspektif Kompilasi Hukum Ekonomi Syariah.

Penelitian ini termasuk penelitian lapangan (field research) yaitu penelitian yang berdasarkan pada data dan informasi dari observasi pengamatan langsung dan wawancara kepada pemilik kambing. Sifat dari penelitian ini deskriptif analisis penggambaran pelaksanaan penyewaan hewan pejantan kambing di Kampung Banjar Negara dan dianalisis menurut Kompilasi Hukum Ekonomi Syariah.

Masyarakat melakukan penyewaan hewan pejantan ini karena sudah Saling percaya selain itu biayanya lebih murah dibandingkan dengan inseminasi buatan. Berdasarkan hasil penelitian, penyewaan hewan pejantan kambing menurut Kompilasi Hukum Ekonomi Syariah sudah memenuhi syarat dan rukun ijarah. Akan tetapi praktek penyewaan hewan pejantan Karena air mani hewan pejantan tidak dapat diukur dan diserah terimakan. Kegiatan ini sudah menjadi tradisi secara turun- menurun, masyarakat juga tidak begitu memahami tentang pelarangan yang ada. Namun Rasulullah Saw, memperbolehkan menerima hadiah tanpa adanya akad sewa.
Jangka Waktu Sewa-Menyewa (Ijarah) Dalam Kitab Undang-Undang Hukum Perdata Pasal 1579 Dan Hukum Islam
Authors: Lilik Erliani
Published: July 2022

Dalam praktik sewa-menyewa, yang dimaksud dengan “waktu tertentu” adalah jangka waktu yang dihitung menurut kelaziman, misalnya jumlah jam, hari, minggu, bulan, dan tahun. Waktu tertentu ini digunakan sebagai pedoman untuk menentukan lamanya sewa menyewa berlangsung, jumlah uang sewa, saat pembayaran uang sewa, dan berakhirnya waktu sewa.

Metode pengumpulan data dilakukan dengan menggunakan metode documenter yang berupa survey kepustakaan dan studi literature. Yakni mengumpukan data yang berupa sejumlah literature yang diperoleh dari perpustakaan dan tempat lain kemudian dipelajari dan telaah sehingga menghasilkan sebuah analisis yang menjadi jawaban dari permasalahan yang menjadi objek hukum.

Adapun teknik dalam analisa data menggunakan metode penelitian yang bersifat deskriptif, analisis, yakni penulis mencoba mendeskripsikan sewa-menyewa dalam dua hukum tersebut kemudian menganalisis kesesuaian Jangka Waktu Sewa-Menyewa (Ijarah) Dalam Kitab Undang-Undang Hukum Perdata Pasal 1579 dan Sewa-Menyewa Dalam Hukum Islam. Dengan menggunakan metode tersebut dapat ditemukan bahwa ada perbedaan konsep pada jangka waktu sewa-menyewa dalam KUHPdt Pasal 1579 dan Hukum Islam.

Berdasarkan hasil penelitian, mengenai jangka waktu sewa-menyewa dalam Kitab Undang-Undang Hukum Perdata Pasal 1579 dan menurut hukum islam, Berdasarkan Kitab Undang-Undang Hukum Perdata Pasal 1579 yang menjelaskan bahwa pihak yang menyewakan tidak dapat menghentikan sewa dengan menyatakan hendak memakai sendiri barang yang disewakan, kecuali jika telah diperjanjikan sebaliknya. Dalam islam, jangka waktu sewa-menyewa (ijarah) tidak ada batas waktunya maka perlu diadakan penagihan sewak-waktu
Tinjauan Hukum Islam Terhadap Upaya Wanita Karir Dalam Menjaga Keharmonisan Rumah Tangga
Authors: Titin Purwaningsih  , Opi Herda Mutiara  , Imam Sujono
Published: July 2022

Salah satu tujuan pernikahan adalah untuk mewujudkan rumah tangga yang harmonis termasuk dengan wanita karir. Salah satu faktor yang mempengaruhi keharmonisan rumah tangga yaitu faktor ekonomi, terkadang permasalahan ekonomi menjadi salah satu pemicu kurangnya keharmonisan dalam rumah tangga karena semakin tingginya kebutuhan yang harus dipenuhi sedangkan penghasilan suami tidak mencukupi. Hal seperti itulah yang mendorong wanita untuk bekerja, meskipun banyak sekali perdebatan terkait dampak positif dan negatifnya. Dampak negatif dari wanita yang bekerja inilah yang sering menjadi permasalahan dalam keharmonisan rumah tangga. Tujuan dari penelitian ini adalah untuk mengetahui bagaimana tinjauan hukum islam terhadap upaya yang dilakukan wanita karir di Dinas Kesehatan Kabupatenn Way Kanan dalam menjaga keharmonisan rumah tangga. Jenis penelitian ini adalah penelitian lapangan, data terdiri dari data primer dan data sekunder. Data primer dalam penelitian ini merupakan data yang diperoleh dari wawancara terhadap wanita karir di Dinas Kesehatan Kabupaten Way Kanan. Sedangkan data sekunder diperoleh dari literatur-literatur yang berhubungan langsung dengan pokok pembahasan. Analisis data menggunakan teknik analisis deskriptif kualitatif. Berdasarkan hasil analisis disimpulkan bahwa upaya yang dilakukan wanita karir di Dinas Kesehatan Kabupaten Way Kanan dalam menjaga keharmonisan rumah tangganya sudah sesuai dengan ketentuan hukum islam. Adapun upaya yang dilakukan yaitu dengan cara saling menghargai, saling mengerti satu sama lain, menjaga komunikasi dengan baik, selalu terbuka dan berdiskusi mengenai penyelesaian masalah-masalah yang dihadapi
Strategi Pemasaran Produk Mudharabah Baitul Maal Wattamwil (BMT) Mentari Kota Gajah
Authors: Asmuni
Published: July 2022

Baitul Maal Wattamwil (BMT) Mentari Kota Gajah merupakan lembaga keuangan syariah dimana didalamnya terdapat produk Mudharabah. Yang melatar belakangi penelitian ini adalah belum banyaknya masyarakat yang mengetahui produk Mudharabah pada BMT Mentari Kota Gajah. Dengan menggunakan rumusan masalah “bagaimana strategi pemasaran produk Mudharabah BMT Mentari Kota Gajah tahun 2021. Adapun tujuan penelitian ini ialah ingin mengetahui strategi pemasaran produk Mudharabah BMT Mentari Kota Gajah tahun 2021.

Dalam hal penelitian ini penulis menggunakan jenis penelitian lapangan yaitu mengenai fakta-fakta dan permasalahan yang ada dilapangan, dengan metode pengumpulan data melalui observasi, interview dan dokumentasi. Kemudian penulis menggunakan metode kualitatif dengan pendekatan deduktif yaitu suatu metode dengan menarik suatu kesimpulan dari hal-hal atau gejala bersifat umum yang kemudian disimpulkan yang bersifat khusus.

Analisis data yang diperoleh penulis dari BMT Mentari Kota Gajah pada tahun 2021 mengenai strategi pemasaran produk Mudharabah maka dapat dianalisa bahwasanya strategi yang digunakan pada BMT Mentari Kota Gajah adalah marketing mix atau bauran pemasaran.

Berdasarkan penelitian dan analisa yang penulis lakukan pada Baitul Maal Wattamwil (BMT) Mentari Kota Gajah pada produk Mudharabah maka diperoleh bahwa metode pemasaran yang dilakukan yaitu dengan melalui marketing mix yaitu: (1) Product mix, (2) Pleace mix, dan (3) Promotion mix. Kemudian strategi pemasaran produk Mudharabah BMT Mentari Kota Gajah sudah sesuai dengan syariah Islam.
Mekanisme Pembiayaan Mudharabah Pada Koperasi Jasa Keuangan Syariah (KJKS) Baitul Maal Wattamwil (BMT) STAI Al-Ma’arif Way Kanan
Authors: Totok Dwi Pambudi
Published: July 2022

Baitul Maal Wat Tamwil adalah lembaga usaha masyarakat yang mengembangkan aspek-aspek produksi dan investasi untuk meningkatkan kualitas kegiatan ekonomi dalam skala kecil dan menengah. Dalam fungsinya BMT selain harus mampu memberikan pelayanan yang baik tetapi juga harus tetap berhubungan secara baik dengan masyarakat sebagai nasabahnya. Hubungan ini dijalankan dengan tujuan agar BMT dapat mengetahui sejauh mana kepuasan nasabah terhadap pelayanan yang diberikan. Kepuasan nasabah ini merupakan bagian terpenting dari BMT. Oleh karena itu harus diberikan pelayanan dengan mutu terbaik, karena tanpa nasabah BMT tidak ada artinya. Kegiatan ni tidak lepas dari usaha BMT untuk memenuhi kebutuhan nasabah. Dari beberapa kebutuhan nasabah tersebut mendorong BMT untuk melakukan mekanisme pembiayaan yang efektif.

Tujuan penelitian ini adalah untuk mengetahui Mekanisme Pembiayaan Mudharabah pada Koperasi Jasa Keuangan Syariah (KJKS) Baitul Maal Wattamwil STAI Al-Ma’arif Way Kanan. Penelitian ini merupakan penelitian kualitatif dengan pendekatan deskriptif. Teknik pengumpul datanya yaitu dengan teknik observasi, interview dan dokumentasi. Sedangkan teknik analisa datanya yaitu dengan pola pikir deskriptif.

Berdasarkan hasil penelitian, diperoleh bahwa Pembiayaan Mudharabah digunakan sebagai salah satu prinsip operasional. Secara operasional, prinsip mudharabah di BMT STAI Al-Ma’arif Way Kanan diartikan sebagai perjanjian kesepakatan bersama antara pemilik modal dan pengusaha dengan ketentuan pihak BMT STAI Al-Ma’arif Way Kanan menyediakan dana dan pihak pengusaha memutar modal dengan dasar bagi hasil keuntungan. Dalam prinsip ini kedua belah pihak sama-sama menanggung resiko sesuai dengan kerugian dan keuntungannya. Perhitungan pendapatan BMT STAI Al-Ma’arif Way Kanan menggunakan pendekatan profit sharing yaitu pendapatan yang dibagikan adalah pendapatan bersih yang sudah dikurangi dengan biaya-biaya operasional. Nisbah bagi hasil dalam pembiayaan mudharabah harus ditetapkan pada akad, penandatanganan pembiayaan sesuai kesepakatan bersama BMT STAI Al-Ma’arif Way Kanan. BMT Fajar Metro dalam Mekanisme akad Mudharabah sudah sesuai dengan syari’at Islam hal ini didasarkan pada bentuk-bentuk implementasinya mulai dari syarat-syarat yang digunakan, prosedur dan ketentuan pengajuan serta prinsip-prinsip dalam implementasinya sudah sesuai dengan syari’at Islam.
Analisis Hukum Islam Tentang Praktik Sewa Menyewa Lahan Pertanian Jagung Tanpa Surat Perjanjian
Authors: Badrun
Published: July 2022

Dalam Islam hubungan antara manusia satu dengan yang lainnya disebut dengan istilah muamalah. Menurut istilah pengertian muamalah dapat dibagi menjadi dua macam yaitu muamalah dalam arti sempit dan pengertian muamalah dalam arti luas menurut munurut Muhammad Yusuf Musa muamalah adalah peraturan-peraturan Allah yang harus diikuti dan ditaati dalam hidup bermasyarakat untuk menjaga kepentingan manusia. Sedangkan muamalah dalam arti sempit menurut Idris Ahmad muamalah adalah aturan-aturan Allah yang mengatur hubungan manusia dengan manusia dalam usahanya untuk mendapatkan alat-alat keperluan jasmaninya. Salah satu bentuk kegiatan muamalah adalah sewa menyewa.

            Jenis penelitian ini adalah penelitian deskriptif. Adapun tujuan penelitian ini adalah untuk mengetahui tentang Analisis Hukum Islam tentang Praktek Sewa Menyewa Lahan Pertanian Jagung Tanpa Surat Perjanjian Studi Kampung Setia Negara Kecamatan Baradatu Kabupaten Way Kanan. Penelitian ini peneliti lakukan di kampung Setia Negara Kecamatan Baradatu Kabupaten Way Kanan. Teknik pengumpulan data yang peneliti gunakan adalah Observasi, Wawancara, dan Dokumentasi. Setelah data terkumpul, maka peneliti melakukan analisis dengan menggunakan Kualitatif yang bersifatdeskiptif.

            Berdasarkan hasil penelitian dapat disimpulkan bahwa pelaksanaan sewa menyewa lahan pertanian jagung tanpa surat perjanjian di Kampung Setia Negara Kecamatan Baradatu berdasarkan akad sewa menyewa lahan pertanian dimanfaatkan dan dikelola lahannya tersebut agar dapat diambil manfaatnya dan hasilnya. Dalam perjanjian sewa menyewa didasari sukarela dan tidak ada unsur paksaan. Perjanjian yang menggunakan akad saling percaya antara satu dan yang lainnya.

            Menurut pandangan hukum Islam, praktik sewa menyewa lahan pertanian jagung tanpa surat perjanjian yang dilakukan masyarakat Kampung Setia Negara Kecamatan Baradatu sudah  memenuhi hukum Islam tetapi didalam perjanjiannya masih belum cukup kuat untuk menjadi bukti apabila sewaktu-waktu terjadinya sengketa yang bisa merugikan para pihak sehingga akan menjadi pertentangan dengan dilakukannya suatu perjanjian sedangkan   ya agar dapat diambil manfaat atau hasilnya. Karena pada hakekatnya sewa menyewa dalam hukum Islam hanya boleh mengambil manfaat, bukan benda atau objeknya.
Implementasi Landasan Hermeneutika Dalam Studi Islam
Authors: Joni Putra  , Rima Yuni Saputri
Published: July 2022

Latar belakang penelitian ini ialah adanya persoalan dalam studi Islam yang di dalamnya mencakup studi teks dan sosial, yang tentunya harus terus dikembangkan sehingga memiliki kekayaan dan varian-varian temuan yang akan bermanfaat bagi eksistensi keilmuan dan memiliki manfaat pragmatis bagi masyarakat. Hasil dari penelitian ini adalah bahwa pendekatan hermenutika dalam studi Islam dipandang sebagai alat bantu dalam membaca, memahami, menjelaskan suatu fakta, teks sumber hukum ajaran Islam, baik al-Qur’an maupun al-Hadis maupun realitas perilaku sosial dan keagamaan masyarakat melalui sebuah interpretasi untuk mengungkapkan makna sesungguhnya dari teks atau realitas tersebut.
Kooperatif Tipe Team Game Tournament Untuk Meningkatkan Aktivitas Dan Hasil Belajar Siswa SDS Madang Jaya Kec. Rebang Tangkas
Authors: Lyna Yuni Artika
Published: July 2022

Hasil belajar siswa yang rendah merupakan wujud dari berbagai masalah yang muncul dari kegiatan pembelajaran. Proses pembelajaran yang tidak sesuai dengan metode pembelajaran akan sangan berdampak pada hasil belajar siswa. Oleh sebab itu penerapan metode pembelajaran oleh guru harus sesuai dengan materi pelajaran yang hekdak diajarkan agar hasil belajar yang dilakukan akan mendapat hasil yang maksimal.

Penelitian ini adalah Penelitian Tindakan Kelas (PTK), peneliti bertindak sebagai pendidik dan pendidik mata pelajaran sebagai observer. Pembelajaran dilakukan selama 2 siklus dengan 6 kali pertemuan. Metode pengumpulan data menggunakan tes tertulis, lembar observasi untuk mengamati aktivitas siswa dan metode dokumentasi, serta wawancara.

Berdasarkan hasil analisis dari penelitian dapat diketahui bahwa dengan penerapan metode Team Game Tournament hasil belajar siswa mengalami peningkatan dari siklus I sampai siklus II. Siklus I hasil belajar siswa mencapai ketuntasan 65% pada siklus II mencapai 80,75%. Berdasarkan hasil analisis dapat disimpulkan bahwa penerapan metode Team Game Tournament dapat meningkatkan hasil belajar siswa. Peningkatan ini merupakan implikasi dari peningkatan aktivitas belajar siswa. Pendidik merasa puas atas penerapan metode Team Game Tournament, dan siswa merasa lebih bersemangat dalam mengikuti Pembelajaran. Peneliti menyarankan untuk sekolah agar memberikan motivasi kepada para pendidik untuk dapat menerapkan Team Game Tournament, khususnya pada matapelajaran yang berhubungan dengan praktik pengalaman belajar