bluuebunny/crossref_metadata_2025 huggingface dataset:
Quilombo Cafundá-Astrogilda: marcos da memória na busca do reconhecimento
Authors: Rodríguez Cáceres Luz Stella
Published: February 2024

No processo de reconstrução do passado e no marco da luta pela regularização fundiária quilombola, as famílias do quilombo Cafundá-Astrogilda organizam os fatos do passado para pensar o seu lugar e momento de luta pelo reconhecimento. Neste texto se exploram as narrativas que contam acontecimentos do passado e que têm significado para uma parte dos moradores do quilombo, localizado na Zona Oeste da cidade do Rio de Janeiro. De origem camponesa, essas famílias, afrodescendentes na sua maioria, compartilham uma história comum, cujas memórias permitem traçar uma periodização que entrecruza os tempos privados e geracionais das memórias familiares com o tempo público. As ditas narrativas compõem marcos de memória, como as compras de terras ao extinto Banco de Crédito Imobiliário e a resistência às ameaças de expropriação por parte dos administradores do Parque Estadual, às quais os habitantes do maciço da Pedra Branca foram expostos.
Exclusão do ICMS da base de cálculo do PIS e da COFINS: principais argumentos do RE Nº 574.706/PR
Authors:   , Oliveira Daiana Lopes de
Published: February 2024

Considerando a alta carga tributária das empresas privadas, a busca por validação de sistemática de cálculo, bem como da composição da base de cálculo à ser tributada, em 15/03/2017 o Tribunal Pleno do Supremo Tribunal Federal (STF) concluiu o julgamento Recurso Extraordinário (RE) n° 574.706/PR e fixou a tese de que o Imposto sobre Circulação de Mercadoria e Serviços (ICMS) não compõe a base de cálculo para a incidência do Programa de Integração Social (PIS) e da COFINS. A chamada Tese do Século, refletiu não só nos cofres públicos com uma diminuição significativa de arrecadação, como também a possibilidade de que o tema reflita na composição da base de cálculo de outros impostos e abertura de um precedente para o ajuizamento de ações de restituição das contribuições pagas em excesso. O presente artigo, procura demonstrar os impactos e o reflexo na carga tributária da exclusão do ICMS da base de cálculo do Pis e da COFINS, a inconstitucionalidade dessa cobrança nos períodos anteriores à pacificação do tema pelo STF, e a diferenciação entre Receita e Faturamento mediante interpretação sob o Ângulo da Constituição Federal e Código Tributário Nacional (CTN) e da tese dos Ministros.
Keragaman Gen Calpastatin pada Ayam Kampung
Authors: Saifullah Saifullah , Pakiding Wempie , Dagong Muh. Ihsan A. , Hikmawaty Hikmawaty
Published: February 2024

Gen calpastatin (CAST) berperan dalam mengontrol sifat kualitas daging. Penelitian ini bertujuan untuk mengetahui keragaman gen calpastatin tiga jenis ayam kampung yang berbeda. Penelitian ini menggunakan motode PCR-RFLP untuk mengamplifikasi fragmen DNA genom gen CAST. Penelitian ini dilaksanakan di Kandang Peternakan CV. Bittara Wanua di Kabupaten Soppeng dan Laboratorium Bioteknologi Terpadu Universitas Hasanuddin. Jumlah sampel yangg digunakan sebanyak 45 ekor dari tiga jenis ayam kampung yang berbeda, yaitu Ayam KUB, ayam Merawang, dan ayam kampung in ovo feeding. Hasil penelitian menunjukkan bahwa genotipe ayam kampung berupa AA dan AG, dengan frekuensi alel dominan A. Gen CAST pada ayam kampung in ovo feeding bersifat polimorfik (frekuensi alel A = 0,93; G = 0,07), sedangkan ayam KUB dan ayam Merawang bersifat monomorfik (frekuensi alel A = 0,97; G = 0,03 pada ayam KUB dan frekuensi alel A = 1,00; G = 0,00 pada ayam Merawang). Nilai Ho dan He ayam kampung in ovo feeding masing-masing sebesar 0,133 dan 0,1289. Ayam kampung in ovo feeding berada dalam keseimbangan Hukum Herdy-Weinberg dengan nilai X2 = 0,0370
Prevalence And Associated Factors Of Burnout Among Bule Hora University Teachers
Authors: Alemishet Ayichluhim
Published: February 2024

The present study intended to assess the prevalence of burnout and its associated factors among teachers at Bule Hora University teachers, South East Ethiopia. A cross-sectional survey design was employed to achieve the objective of the study. Using a simple random sampling technique, 220 volunteer teachers who were actively working at Bule Hora University during the study period were selected. Standardized instruments like the Maslach Burnout Inventory (MBI), General Self-efficacy Scale (GSE), Rosenberg Self-esteem Scale (RSE), and Life Orientation Test-Revised (LOT-R) were used to collect the data, whereas quantitative data analysis techniques such as frequency, percentage, and linear regression analysis were utilized to analyze the collected data. In this study, a high percentage of emotional exhaustion (EE) (42.73%) and depersonalization (DP) (45.45%) and a low percentage of personal accomplishment (PA) (56.36%) indicated a prevalence of burnout. The study also showed a significant positive correlation between PA and self-efficacy, whereas optimism had a negative correlation with EE and DP. While self-efficacy significantly predicted PA, optimism significantly predicted both EE and DP. From this result, we can conclude that the prevalence of burnout is attributed to self-efficacy and optimism. Therefore, concerned bodies ought to design appropriate interventions that incorporate self-efficacy and optimism to manage university teachers' burnout.
GOVERNMENT EXPENDITURES ON HOUSEHOLD CONSUMPTION – LEVEL, CHANGES, AND THEIR RELATIONSHIP WITH SOCIO- -ECONOMIC DEVELOPMENT INDICATORS IN EUROPEAN COUNTRIES
Authors: Piekut Marlena
Published: February 2024

Aim: The aim of this article is to examine changes in government expenditures on household consumption in European countries and the relationship of these expenditures with socio-economic indicators. Methods: The study is based on data analysis from 36 European countries, using the Eurostat database and various rankings such as the Happiness Index, Human Development Index, Sustainable Development Goals, and Social Progress Index. The analysis focused on the trends in government expenditures on household consumption and aimed to explore the association between these expenditures and socio-economic indicators. Results: Significant changes in the share of government expenditures on household consumption in the GDP were observed among the studied countries during the period from 2011 to 2022. Some countries increased their expenditures, while others decreased them. Cluster analysis revealed four groups of countries based on the share of government expenditures on household consumption in GDP. Conclusions: There was no direct correlation between the level of government expenditures on household consumption and socio-economic indicators among the studied countries. Instead, variations in socio-economic development were observed among different groups of countries, regardless of the level of government expenditures on household consumption.
Use of glucagon-like peptide-1-receptor-agonists and risk of serious renal events: Scandinavian cohort study
Authors: Pasternak Björn , Wintzell Viktor , Eliasson Björn , Svensson Ann-Marie , Franzén Stefan , Gudbjörnsdottir Soffia , Hveem Kristian , Jonasson Christian , Melbye Mads , Svanström Henrik , Ueda Peter
Published: February 2024

Objective

To
assess the association between use of GLP1-receptor-agonists and risk of
serious renal events in routine clinical practice.

Research Design and Methods

Cohort
study using an active-comparator new-user design and nationwide register data
from Sweden, Denmark and Norway, 2010-2016. The cohort included 38,731 new
users of GLP1-receptor-agonists (liraglutide 92.5%;
exenatide 6.2%; lixisenatide 0.7%; dulaglutide
0.6%), matched 1:1 on age, sex and propensity score to a
new user of the active comparator, dipeptidyl-peptidase-4 (DPP-4) inhibitors. The
main outcome was serious renal events, a composite including renal replacement
therapy, death from renal causes and hospitalization for renal events.
Secondary outcomes were the individual components of the main outcome. Hazard
ratios (HRs) were estimated using Cox models and an intention-to-treat exposure
definition. Mean (SD) follow-up time was 3.0 (1.7)
years.

Results

Mean
(SD) age of the study population was 59 (10) years and 18% had cardiovascular
disease. A serious
renal event occurred in 570 users of GLP1-receptor-agonists (incidence rate 4.8
events per 1000 person-years) and in 722 users of DPP4 inhibitors (6.3 events
per 1000 person-years; hazard ratio [HR] 0.76, 95% CI 0.68-0.85; absolute
difference -1.5 [-2.1 to -0.9] events per 1000 person-years). Use of
GLP1-receptor-agonists was associated with a significantly lower risk of renal
replacement therapy (HR 0.73 [0.62-0.87]) and hospitalization for renal events
(HR 0.73 [0.65-0.83]) but not death from renal causes (HR 0.72 [0.48-1.10]). When
using an as-treated exposure definition in which patients were censored at
treatment cessation or switch to the other study drug, the HR for the primary
outcome was 0.60 (0.49-0.74).

Conclusion

In this large cohort of
patients seen in routine clinical practice in three countries, use of
GLP1-receptor-agonists, as compared with DPP4 inhibitors, was associated with a
reduced risk of serious renal events.
Reisen mot kontinuerlig utvikling i offentlig sektor
Authors: Strømmen Jarle
Published: February 2024

Artikkelen «Reisen mot kontinuerlig utvikling i offentlig sektor» diskuterer hvordan utvikling i offentlig sektor i Norge har utviklet seg de siste årene gjennom økt vekt på produktorientering. Tidligere har det vært vanlig å bruke store programmer og prosjekter for å håndtere digital transformasjon og endring. Dette har vært viktig for å sørge for kontroll på investeringer og håndtere større og komplekse løft på vår digitaliseringsreise. Men nå ser flere på muligheten for å gå i retning av kontinuerlig utvikling av løsninger og prosesser, i stedet for periodisk oppgradering og modernisering gjennom programmer og prosjekter. Allerede nå er produktorientering på vei til å spre seg som den viktigste tilnærmingen til utvikling i offentlig sektor. Endringene i teknologi skjer så raskt at vi ofte ikke kan vite hva vi trenger av endringer i løsninger og prosesser bare ett eller to år frem i tid. For å kunne raskere tilpasse oss endringer og økt usikkerhet har vi behov for å finne nye måter å organisere utviklingen på. Dette er en spennende reise, men den innebærer også noen utfordringer.
Abstract in English
The article "The journey towards continuous development in the public sector" discusses how development in the public sector in Norway has evolved in recent years through an increased focus on product orientation. In the past, using large programs and projects to manage digital transformation and change was common. This was important to ensure control over investments and handle larger and complex lifts on our digitization journey. Now, however, more people are looking at the possibility of continuous development of solutions and processes, instead of periodic upgrading and modernization through programs and projects. Product orientation is already on its way to becoming the most important approach to development in the public sector. Changes in technology happen so quickly that we often cannot anticipate changes we may need in solutions and processes just one or two years in the future. In order to adapt to faster changes and increased uncertainty, we need to find new forms of organizing development. This is an exciting journey, but one that also comes with its own challenges.
Analysis of Nursing Professionals Criteria Regarding the Application of Ostomy Devices at Each Stage of the Care Process
Authors: Santana Casanova Kenlis Alejandra
Published: February 2024

Objective: To analyze the opinions and criteria of nursing professionals regarding the use of ostomy devices at each stage of the care process, considering both the characteristics of the ostomy and the patient. Method: A multicentered, cross-sectional descriptive study based on a national survey conducted among nursing professionals involved in the care of ostomy patients. Results: Despite the availability of various ostomy devices in most centers, patients are typically instructed in the use of twopiece devices upon hospitalization, which potentially explains their higher frequency of use. Discussion and Conclusion: Case presentations or industry-sponsored research have been identified where the use of specific devices is not justified, but rather their characteristics. Conducting a nationwide survey provides a comprehensive understanding of the criteria followed by nursing professionals in the care and management of ostomy patients, as well as in the selection and/or change of ostomy devices
Unraveling the Molecular Complexity of Eosinophil Dynamics in Sickle Cell Anemia: An Overview of the Literature
Authors: Ifeanyi Obeagu Emmanuel
Published: February 2024

Sickle Cell Anemia (SCA) is a genetic disorder characterized by abnormal hemoglobin, leading to distorted red blood cells and a myriad of clinical complications. Recent research has highlighted the role of eosinophils in the pathophysiology of SCA, emphasizing the need to explore their dynamics from a molecular perspective. This review synthesizes current knowledge on seven key aspects of eosinophil involvement in SCA, shedding light on the intricate molecular mechanisms driving their activation, recruitment, and impact on disease progression. We delve into the molecular crosstalk between eosinophils and cytokine signaling, their contribution to endothelial dysfunction, and their role in oxidative stress. Furthermore, the review examines the molecular basis of eosinophil-induced vaso-occlusive crises and the formation of eosinophil extracellular traps. Lastly, we discuss the therapeutic implications of understanding eosinophil dynamics in SCA and propose future research directions. This comprehensive exploration aims to enhance our understanding of the molecular intricacies underlying eosinophil involvement in SCA, paving the way for targeted therapeutic interventions to alleviate the burden of this debilitating disease.
Epidemic Mosaic: State-Wise Patterns and Impacts of Covid-19 in India
Authors: Hoper S Sheeba
Published: February 2024

After being discovered for the first time in Wuhan, China in December 2019, the extremely contagious coronavirus illness (COVID-19) quickly spread to 212 nations and territories worldwide, affecting millions of people. The sickness was discovered for the first time in India, a sizable nation of 1.3 billion people, on January 30, 2020, in a student who was returning from Wuhan. The extremely contagious coronavirus illness 2019 (COVID-19) was initially identified in Wuhan, China, in December 2019. Over two million people have been verified to have been infected by the disease, which has spread to 210 different nations and territories worldwide. The sickness was initially discovered in India on January 30, 2020, in Kerala in a student who had just returned from Wuhan. Thus far, 17615 individuals have been verified to be infected nationwide (19 April 2020). The majority of studies and press reports center on the total number of infected individuals in India. But considering the vastness and diversity of India, it could be wise to examine the disease's spread across each state independently, as well as the nation as a whole. The goal of this research is to present a thorough overview of the COVID-19 pandemic analysis in India, including state-by-state death rates and management strategies. We obtained articles from the official website that describe the COVID-19 management approach and the death rates in each state, as well as up-to-date data from 2022 and 2023. With 4.2 billion people, India is the nation with the biggest population. The nation's economy grew significantly as a result of this disaster. India saw the third-highest number of deaths worldwide and the second-highest number of confirmed positive cases. Nevertheless, considering the vastness and diversity of India, it is crucial to examine the disease's spread in each state independently, as conditions in each vary greatly. We analyses data on the number of infected individuals in each Indian state in this research (limited to those states with sufficient data for analysis). Our analysis is intended to assist state governments in more effectively allocating their little healthcare resources in anticipation of emerging health crises.
U.S. Foreign and Security Policy in the First Half of the Biden Administration
Authors: Novotný Antonín , Potočňák Adam
Published: February 2024

In an era of ongoing strategic confrontation between the world's major powers, the security and foreign policy of the United States, the still dominant global superpower, is also undergoing constant and turbulent changes personified particularly by the arrival of new presidential administrations. In this regard, the ascension of the administration of current President Joe Biden in January 2021 is another milestone for the analysis of U.S. security policy. The presented article thus analyses the foreign and security policy of the United States of America in the January 2021-January 2023 period, that is, in the first half of the Joe Biden administration's term. The authors use the foreign policy analysis method to critically analyse Biden's foreign and security policy in three distinctive geopolitical regions: the Indo-Pacific, Europe, and the Middle East. The authors utilise Biden's policy in these regions as a case study to test Pavel Hlaváček's theory from 2018, according to which the national mood of the U.S. foreign currently finds itself in an introverted phase. The authors conclude that the theory remains valid by analysing Biden's foreign and security policy. Based on the 2022 midterm elections result, they also support Hlaváček's assumption that another alteration in the national mood in the U.S. foreign policy should not be expected sooner than in the mid-2030s. Nonetheless, the validity of the applied theory and the conclusions we have drawn from it will be conclusively tested by all upcoming presidential or midterm elections, with the nearest ones as early as November 2024.
The Effectiveness of using Quizlet as digital learning to improve vocabulary mastery of junior high school students
Authors: Nur Serliah , Putri Nurhalisa Eka
Published: February 2024

The aim of this study is to determine the effectiveness of using Quizlet as a digital learning medium to improve the vocabulary mastery of junior high school students. This study applied a quasi-experimental design with pre-test and post-test. The population of this study consisted of the 8th-grade students of MTsN 1 Kota Makassar. Purposive sampling was utilized by the researchers to choose 80 students as a sample and divided them into two classes, experimental and controlled classes. This study used a vocabulary test as the instrument. The vocabulary test was used to determine whether the 'students' vocabulary mastery had improved following the treatment or not. The result of the study shows that there was improvement of 'students' vocabulary after using Quizlet as digital learning media. This is evidenced by the t-test significant value 0.000<0.05, which means that H1 is accepted and H0 is rejected. Therefore, using Quizlet as digital learning media is effective to improve 'students' vocabulary mastery. Quizlet is one of application that can be used as digital learning media with many features that can support the learning process in individuals and groups. Quizlet can also be used in online and offline situations.
The Phenomenon of Bandung Street Musicians: Interaction with Road Users and Legal Aspects
Authors: Rizal Hendra , Sukmayadi Yudi
Published: February 2024

The objective of this study is to investigate the phenomenon of street musicians at Bandung Traffic Lights from the perspective of traffic law and road transportation. The research method employed is a qualitative approach with a specific focus on the interaction between road users and aspects of traffic law and road transportation concerning street musicians at Bandung Traffic Lights. The research methodology includes observations, interviews, documentation, and in-depth analysis. The research findings reveal that the presence of street musicians at Bandung Traffic Lights has a diverse impact on commuters; some find it entertaining, while others feel distracted. From the standpoint of traffic and road transport law, the activities of street musicians on the sidewalk or roadway may be considered violations of Article 275, paragraph (1), and Article 28, paragraph (2), of Law No. 22 of 2009 on Traffic and Road Transport. The implications of this study underscore the significance of arts education in fostering a sense of discipline among street musicians. This research can help ensure that their artistic performances are more focused and orderly without causing disruption to road users.
Implementation of Indah Mayang Embroidery in Pariaman City to Increase Sales of the Creative Fashion Industry
Authors: Irja Irja , Rahmat Fadri , Febrianty Syielvi Dwi , Surya Wirma
Published: February 2024

The creative economy is a new era of economic concepts that prioritizes information and creativity and relies on human resources' ideas as the primary production factor in economic activities. Pariaman City's traditional embroidered cloth business is one of the creative industries of the fashion sub-sector. The Embroidery Naras fabric business in Kota Pariaman has seen a drastic decrease in sales turnover since the Covid-19 pandemic, so entrepreneurs are looking for alternative solutions to increase their sales again. This research aims to find solutions to the problems faced by embroidered fabric craftsmanship, specifically how to increase sales volume after the covid-19 pandemic by advancing the creative embroidered fashion industry through the role of increasing production, creativity, and innovation. There are two types of data used: primary data and secondary data. Data collection, data reduction, data presentation, and conclusions are the data analysis techniques used in this study. According to the findings, increasing production played only a 33% role. This demonstrates that craftsmen play a smaller role in increasing production to 100%. While the criteria for increasing creativity reaches 70%, it demonstrates that it plays an important role in increasing sales volume. It reaches 15% for the global marketing criteria, indicating that it does not play a role in global marketing, and it reaches only 3% for the use of technology, indicating that it does not play a role in the production process. Similarly, increasing revenue by 33%, As a result, it plays a smaller role in increasing revenue through direct and online sales.
Diseño de un sistema de valuación masiva de suelo urbano fundamentado en la teoría de la renta de la tierra. Aplicación al caso de Cuenca, Ecuador
Authors: Salazar-Guamán Ximena , Pauta-Calle Fernando , Peralta-Peñaloza Cristina , González-Llanos Mónica , Sinchi-Tenesaca Edison
Published: February 2024

Las municipalidades, frente a la obligatoriedad de generar avalúos prediales, predominantemente han empleado el método de comparación, caracterizado por someterse a las distorsiones del mercado de suelo, excluyendo la consideración explícita de factores que lo valorizan. En este artículo se expone un método de valuación masiva del suelo urbano basado en la generación de rentas de suelo que valorizan la propiedad y que, en su forma capitalizada, se expresan en su precio. A través de la aplicación en la ciudad de Cuenca, se establece un conjunto de procedimientos para la determinación del precio unitario base, identificando para ello el capital incorporado al suelo en infraestructuras y equipamientos, y cuantificando las rentas primarias y secundarias más relevantes a partir de las expresiones de la estructura espacial de los usos de suelo vinculadas a su generación. Los resultados obtenidos demuestran que la teoría de la renta de la tierra es aplicable a la valuación masiva del suelo urbano con fines catastrales, obteniendo un significativo grado de comprensión sobre la conformación de los precios del suelo en la ciudad asociados a sus dinámicas.
Um lagarto de Timor ou a poesia fraterna de Leonel Neves
Authors: Marques João Minhoto
Published: February 2024

Embora Leonel Neves seja sobretudo associado a obras para infância, ele é igualmente autor de um conjunto assinalável de livros de poesia. A atenção ao mundo, ao outro e à poesia são características da sua poética particularmente visíveis nas obras de maturidade, como Memória de Timor-Leste, embora estejam presentes ao longo do seu percurso literário. Este artigo estuda a poesia de Leonel Neves, ocupando-se das referidas características, da coerência da poética e do caso particular do memorial timorense.
Accounting data governance and its influence on financial report quality: Insights from commercial banks
Authors: Alshehadeh Abdul Razzak , Elrefae Ghaleb Awad , Yaseen Saad G. , Aljawarneh Nader Mohammad , Al-khawaja Haneen A.
Published: February 2024

This study aimed to measure the impact of implementing mechanisms of accounting data governance, represented by International Accounting Standards, internal auditing, external auditing, audit committees, disclosure and transparency, and performance evaluation, on the quality of financial reporting data for the commercial banks listed on the Amman Stock Exchange, totaling (15) banks. To achieve the objectives of this study, a descriptive-analytical approach was adopted by developing a questionnaire to collect the primary data measuring the study variables. The questionnaire was distributed to employees in the financial and control departments of these banks, with a total of (375) respondents from the total study population of (733) individuals. Appropriate statistical methods were used to analyze the data, test hypotheses, and the results of this study revealed a strong positive impact of five variables of accounting data governance mechanisms on achieving the quality of financial reporting data. These variables are ranked from highest to lowest in terms of the strength of impact and correlation with the quality of financial reports: disclosure and transparency, external auditing, International Accounting Standards, internal auditing, and audit committees. However, there was no impact of the performance evaluation governance variable on achieving the quality of financial reporting data. These results call on the management of commercial banks in the study to commit to the objective implementation of the requirements of accounting data governance mechanisms as stipulated by international professional assemblies.
Pulse-wave analysis during routine blood pressure measurement shows potential to distinguish between sinus and nonsinus rhythm
Authors: Yang Chung-Chun , Chan I-Ping , Hsueh Tung , Lin Shiun-Long
Published: February 2024

OBJECTIVE

To investigate whether pulse-wave analysis (PWA) performed by trained evaluators facilitates detection of nonsinus rhythm.

ANIMALS

Same-day, high-definition oscillometry pulse-wave data and ECG results of 155 animals (144 dogs and 11 cats) were analyzed.

METHODS

In this cross-sectional study, we enrolled 18 participants from various backgrounds, all of whom received PWA training. The ability to distinguish between sinus and nonsinus rhythms was assessed using receiver operating characteristic curve analysis. The pulse-wave datasets were divided into 5 ECG categories. Agreement between ECG diagnoses and PWA-based arrhythmia detection was evaluated using Cohen κ values, and the correlation between the academic year of veterinary students and their κ values was assessed.

RESULTS

All cardiology researchers demonstrated satisfactory accuracy in distinguishing pathological rhythms using PWA (area under the curve, 0.704 to 0.761), with the highest accuracy in detecting atrial fibrillation (area under the curve, 0.811 to 0.845). Fair agreement with ECG categorization was achieved by all 3 cardiology researchers, 2 of 5 general practitioners, and 3 of 10 veterinary undergraduates. The veterinary undergraduates' years of study were correlated with their diagnostic performance (Spearman ρ = 0.658; P = .019).

CLINICAL RELEVANCE

PWA during routine noninvasive blood pressure measurement showed significant potential for the detection of pathological arrhythmias, notably atrial fibrillation. This approach yielded improved effectiveness when it was used by veterinarians with cardiology experience. Thus, introducing hands-on training courses, particularly those focused on cardiology and interactive workshops, may enable frontline veterinarians to promptly identify arrhythmias using PWA, facilitating timely ECG examinations or referrals.
Intranasal booster vaccination of beef steers reduces clinical signs following experimental coinfection with BRSV and BHV-1 without reducing shedding of BRD-associated bacteria
Authors: Martínez David A. , Chamorro Manuel F. , Passler Thomas , Huber Laura , Falkenberg Shollie , Walz Paul H. , Thoresen Merrilee , Raithel Gage , Silvis Scott , Dimitrov Kiril M. , Stockler Ricardo , Woolums Amelia R.
Published: February 2024

OBJECTIVE

To determine the efficacy of primary or booster intranasal vaccination of beef steers on clinical protection and pathogen detection following simultaneous challenge with bovine respiratory syncytial virus and bovine herpes virus 1.

METHODS

30 beef steers were randomly allocated to 3 different treatment groups starting at 2 months of age. Group A (n = 10) was administered a single dose of a parenteral modified-live vaccine and was moved to a separate pasture. Groups B (n = 10) and C (10) remained unvaccinated. At 6 months of age, all steers were weaned and transported. Subsequently, groups A and B received a single dose of an intranasal modified-live vaccine vaccine while group C remained unvaccinated. Group C was housed separately until challenge. Two days following vaccination, all steers were challenged with bovine respiratory syncytial virus and bovine herpes virus 1 and housed in a single pen. Clinical and antibody response outcomes and the presence of nasal pathogens were evaluated.

RESULTS

The odds of clinical disease were lower in group A compared with group C on day 7 postchallenge; however, antibody responses and pathogen detection were not significantly different between groups before and following viral challenge. All calves remained negative for Histophilus somni and Mycoplasma bovis; however, significantly greater loads of Mannheimia haemolytica and Pasteurella multocida were detected on day 7 postchallenge compared with day −2 prechallenge.

CLINICAL RELEVANCE

Intranasal booster vaccination of beef steers at 6 months of age reduced clinical disease early after viral challenge. Weaning, transport, and viral infection promoted increased detection rates of M haemolytica and P multocida regardless of vaccination status.
MODIFIKASI RAK PENYIMPANAN FREON ERGONOMIS DENGAN MENGGUNANKAN METODE VDI 2221
Authors: Calvin  , Daywin Frans Jusuf , Andres
Published: February 2024

PT. Wijaya Anugerah Abadi adalah perusahaan yang bergerak di bidang jasa yang berhubungan dengan air conditioner baik dari segi pemasangan, pemindahan maupun maintenance. Perusahaan ini melayani dari aspek penjualan, instalasi, service, maupun repair untuk semua kebutuhan perorangan, perkantoran, pabrik, dll. Perusahaan membutuhkan banyak jenis tabung freon untuk menunjang pekerjaan mereka. Penyimpanan tabung freon bila disejajarkan dibawah sangat memakan ruang dan menyulitkan teknisi untuk mengidentifikasi jenis tabung freon karena beberapa tabung freon memiliki warna yang sama, oleh sebab itu dalam penelitian ini penulis berupaya untuk membuat sebuah rak penyimpanan tabung freon yang diharapkan dapat mempermudah teknisi dalam mengidentifikasi tipe tabung freon yang dibutuhkan, selain itu rak penyimpanan ini diharapkan bisa meningkatkan efisiensi ruang dari perusahaan. Pengumpulan dan pengolahan data meliputi beberapa hal yaitu data responden, pertanyaan prasyarat produk dan pertanyaan riset produk. Kuesioner ditujukan untuk memperoleh data responden dalam mengunakan alat yang ingin dirancang. Kemudian, penggunaan kuesioner Nordic Body Map yang bertujuan untuk mengetahui ketidaknyamanan kerja yang dirasakan oleh pekerja. Peneliti akan melanjutkan perancangan yang sesuai dengan kubutuhan perusahaan. menggunakan metode VDI 2221. Berdasarkan hasil pengamatan dan wawancara dengan pekerja, dapat disimpulkan bahwa masih banyak keluhan fisik yang dialami oleh pekerja, sehingga penelitian ini difokuskan untuk mengurangi keluhan fisik pekerja. Rancangan rak penyimpanan tabung freon yang dirancang pada penelitian ini ditujukan untuk mengurangi keluhan fisik para pekerja dalam mengambil dan menyimpan tabung freon.
Optimization of Welded Beam Design Problem Using Water Evaporation Optimization Algorithm
Authors: A. H. Alkurdi Ahmed
Published: February 2024

This paper introduces a novel approach to tackle the Welded Beam Design Problem through the application of the Water Evaporation Optimization Algorithm (WEOA), a nature-inspired metaheuristic. The problem involves finding the optimal dimensions of a welded beam that can support a given load while minimizing its weight. The Water Evaporation Optimization Algorithm draws inspiration from the evaporation process and water droplet movement in nature. The design is formulated as an optimization challenge with beam dimensions as variables and incorporate constraints such as allowable stress and geometric limitations. The fitness function is tailored to evaluate each candidate solution based on load-bearing capacity and weight. To demonstrate the efficacy of the proposed method, extensive experimental evaluations are conducted. Comparisons with traditional optimization techniques highlight the WEOA's superior convergence and global search capabilities. Real-world case studies further illustrate the practical applicability of the optimized welded beam designs, showcasing their cost-effectiveness and high-performance characteristics. The results underscore the potential of the Water Evaporation Optimization Algorithm as a robust and efficient tool for tackling the welded beam design problem. The approach provides engineers with valuable support in achieving optimized beam designs, leading to improved structural performance and material utilization.
Molecular characterization of diosgenin biosynthesis in different organs of Trigonella foenum-graecum L.
Authors: Kwon Do Yeon , Lim Jinsu , Sathasivam Ramaraj , Uddin Md. Romij , Kim Jae Kwang , Park Sang Un
Published: February 2024

Fenugreek, an annual herb, is a significant source of diosgenin, a triterpene with bioactive properties. This study aimed to molecularly characterize diosgenin biosynthesis in various organs of fenugreek, including flowers, immature leaves, developing leaves, mature leaves, stems, roots, and pods. The biosynthetic pathway involves vital enzymes such as squalene synthase, squalene monooxygenase, cycloartenol synthase, and Sterol-3-ß-glucosyl transferase. The study found that flowers and roots exhibited the highest gene expression levels, indicating their potential significance in diosgenin biosynthesis. Diosgenin content was quantified using high-performance liquid chromatography, with seeds being the primary source. The findings suggest that fenugreek offers a cost-effective and rapid alternative to yam for diosgenin production, and the differential accumulation of diosgenin in different plant organs underscores the importance of understanding organ-specific biosynthesis. This comprehensive analysis provides valuable insights into fenugreek’s potential as a bioresource for diosgenin and its diverse applications in medicine and agriculture.
Numerical investigation of combustion in a panela furnace using openfoam
Authors: García Sánchez Gabriel F. , Chacón Velasco Jorge L. , Fuentes Díaz David A.
Published: February 2024

To develop biomass combustion as a viable renewable energy source it is necessary to improve the furnace efficiency and investigate the potential of agricultural wastes as fuels. Computational Fluid Dynamics (CFD) modeling is a valuable tool to accomplish these objectives, OpenFOAM is a powerful open-source CFD software that has been little used in this type of application. This paper reports the study of combustion in a device of great importance for Colombia, the panela furnace, using a model developed in OpenFOAM. The combustion chamber of a Ward-Cimpa furnace, measuring 2.68 m in width and 3.32 m in height was modeled. This model was validated, by comparing the simulated values of CO and temperature at the furnace exit with data taken from literature, resulting in differences of 13.72 % and 12.23 % respectively. These discrepancies are slightly lower than those reported in other studies about the subject. The model was employed to analyze the effect of the air-flow rate on the combustion performance. The findings indicate that the increase in air-flow causes an increase in combustion activity manifested in higher temperature and CO2 emissions, which could indicate that in common operational conditions, the furnace operates under deficient air conditions and its performance could be improve by using higher air flow rates.
KUALITAS LAPORAN KEUANGAN: LATAR BELAKANG PENDIDIKAN DAN PENGALAMAN INTERNASIONAL CFO
Authors: Kaban Melania Berta Uli , Ferby Mutia Edwy
Published: February 2024

Quality financial reports are very necessary for the smooth running of company operations. Companies need competent managers to improve the quality of financial reports. Incompetent managers can result in poor-quality financial reports, causing information asymmetry, damage to the company's reputation, and decreased investor confidence which can hamper the company's operational activities. This research aims to determine the effect of the Chief Financial Officer (CFO) who is a graduate of a reputable university and has international experience in the field of finance on the quality of financial reports. This research was conducted on 563 companies listed on the IDX from 2010 to 2019. Through regression Generalized Least Square (GLS), research finds that CFOs who graduate from reputable universities tend to be able to improve the quality of financial reports, but not CFOs who have international experience in the financial sector. This research shows that the CFO's educational background is very important in supporting the improvement of the quality of financial reports. Therefore, companies must pay attention to the CFO's educational background to support the manager's performance in improving the quality of financial reports.
PENYELENGGARAAN PERIZINAN BERUSAHA MENURUT PERATURAN DAERAH KOTA BOGOR NOMOR 1 TAHUN 2023 (STUDI KASUS RESTORAN MIE GACOAN)
Authors: Muhammad Arkaansyah  , Ferry Edwar
Published: February 2024

There are businesses in Bogor City that violate Article 10 of the Bogor Municipal Regulation No. 1, 2021 and do not have a business license. Its location is Mie Gacoan, located on Jalan Yasmin West Bogor. Originally, this Gacoan Mie restaurant had only NIB (Business Identification Number), i.e. corporate identity or registration mark. The government makes policy to govern the procedural arrangements established in accordance with the activities of Gacoan Noodles Restaurant. The question is whether the actions of the local government will be legally justified if the Mie Gacoan restaurant violates regulations in the Bogor city area but is allowed to continue as long as the regulations remain unclear. The research method used is normative research, the nature of the study is descriptive, the data used are primary and secondary data, library research is used to collect data, data analysis is qualitative, the inferential method uses deductive methods. Preferably, regional regulations should include general principles of good governance, licensing requirements and compliance with product standards such as the Job Creation Act and provisions of regional regulations. It should be consistent at Freies Ermessen.
ISTILAH MENGUASAI TERHADAP UMKM DALAM HUBUNGAN KEMITRAAN DENGAN BENTUK INTI-PLASMA
Authors: Intan Purwanti  , Anna Maria Tri Anggraini
Published: February 2024

In the modern business landscape, large and small companies frequently form collaboration agreements with micro, small, and medium-sized enterprises (MSMEs), creating mutual benefits. This study investigates the interpretation of 'ownership' and/or 'control' of MSMEs as business partners in partnerships, examining the application of criteria in two KPPU decisions (Number 21/KPPU-K/2019 and Number 03/KPPU-K/2021). Using normative and descriptive research methods with primary and secondary data, the study finds that 'ownership' implies an unequal condition resulting in a loss for one party, while 'control' involves decision-taking. The decisions reveal instances of domination by large businesses over MSMEs, each with distinct criteria for control and/or ownership. The study recommends KPPU to formulate guidelines clarifying the terms 'owning' and/or 'controlling' concerning medium/large businesses towards MSMEs.
PEMUNGUTAN SUARA ULANG DALAM PEMILIHAN BUPATI KABUPATEN INDRAGIRI HULU PROVINSI RIAU (STUDI PUTUSAN MAHKAMAH KONSTITUSI NOMOR 93/PHP.BUP-XIX/2021)
Authors: Regina Zetia  , Wiratno
Published: February 2024

The Local Election in Indragiri Hulu Regency witnessed multiple infringements. Consequently, in line with Constitutional Court Decision No. 93/PHP.BUP-XIX/2021, a new election for regent and deputy regent is mandated. This study focuses on the grounds for requesting a recount in the election dispute for the Regent of Indragiri Hulu Regency and explores the legal implications of a re-vote as per Constitutional Decision No. 93/PHP.BUP-XIX/2021. Employing a normative legal research approach. Secondary data, gathered through a literature review, is qualitatively processed, and conclusions are drawn through deductive logic. Research findings reveal violations such as breaching PKPU provisions, manipulating the vote count recapitulation, failure to submit Model C notifications to the Election Supervisory Body, tampering with certain ballots, and the lack of neutrality by village heads violate Article 2 of Law No. 7 of 2017 concerning General Elections and Article 22E of the 1945 Constitution. This provides a substantial basis for implementing a recount in accordance with Constitutional Decision No. 93/PHP.BUP-XIX/2021.
Sudden sensorineural hearing loss
Authors: Niemczyk-Cieślak Elżbieta , Raczkowska Karolina , Zawadzka-Głos Lidia
Published: February 2024

Sudden sensorineural hearing loss (SSNHL), commonly known as sudden deafness, is an increase of bone and air conduction thresholds of greater than or equal to 30 decibeles affecting at least three consecutive frequencies within a 72-hour window. The loss of hearing is commonly accompanied by tinnitus and, rarely, vertigo. The vast majority of SSNHL is of unknown cause. Even 32 to 65% of cases of SSNHL may recover spontaneously. Treatment includes systemic and topical steroids and hyperbaric oxygen therapy (HBOT). Antivirals, thrombolytics, vasodilators, or vasoactive substances should not be routinely prescribed. Patients who have local neurologic findings require computed tomography scan of a head. A retrocochlear pathology should be excluded by obtaining magnetic resonance imaging or auditory brainstem response. The follow-up audiometric evaluation should be obtained at the conclusion of treatment and within 6 months of completion of treatment. The presentation of SSNHL in pediatric population is commonly delayed. Treatment options are similar to those of adults but the hearing recovery rate is higher.
Nasal glial heterotopia in a 5-month-old girl – a case report
Authors: Teo Jia Jia , Kwast Piotr , Nossier Razan , Zawadzka-Głos Lidia
Published: February 2024

Nasal glial heterotopia is a rare congenital mass that is more commonly noted in infants. We report a case of nasal glial heterotopia in a 5-month-old girl initially presenting with unilateral nasal obstruction. Diagnostic imaging showed a tissue mass in the nasal cavity. The mass was resected via endoscopic surgery. We present the approach to radiological examination and clinical course of the case. In cases of infant nasal glial heterotopia recurrence of the mass is possible if it is not completely excised, so it is essential to be careful during the procedure and perform routine follow-ups. Differential diagnosis includes mainly meningocele and encephalocele, polyps and nasal dermoid cyst. Although nasal glial heterotopia is a rare condition, it should be taken into consideration in diagnosis of infants with nasal obstruction.
Anal canal cancer – two case reports
Authors: Glinkowski Sławomir , Marcinkowska Daria
Published: February 2024

The paper presents two cases of female patients with anal canal cancer who were admitted to the Department of General Surgery in a regional hospital at various stages of diagnosis and treatment. The first patient was initially operated on for gastrointestinal obstruction caused by a sigmoid tumour. It was histopathologically found to be G2 invasive adenocarcinoma of the sigmoid colon. The patient had a history of previously diagnosed and untreated chronic lymphocytic leukaemia. One year after the first surgery, she was qualified for gastrointestinal continuity restoration. The pre- and intraoperative period were uneventful. Five years after her first surgery, the patient reported for a medical appointed due to a bleeding tumour of the anal margin. Histopathological findings confirmed a malignant lesion – G2 invasive keratinizing squamous cell carcinoma of the anal canal. Human papilloma virus (HPV) was also detected. The patient received radiotherapy, after which the treatment was considered completed. The second patient reported for a medical appointed due to a suspected haemorrhoidal disease. She was qualified for rectoscopy with biopsy. Histopathology showed G3 non-keratinized basaloid squamous cell carcinoma invading the anal canal. HPV was also detected. The patient received chemoradiotherapy, after which the treatment was considered complete.
Postpartum anal sphincter injury – overlap suturing. Case report
Authors: Głowacki Szymon , Krasińska Katarzyna , Venhura Alesia , Białczak Zbigniew
Published: February 2024

Injury to the anal sphincter is a challenging clinical problem that may be encountered by any doctor in their daily practice. The most common injuries are associated with complicated childbirth, traffic accidents and impalement-type injuries. Depending on their course, injuries with or without sphincter muscle disruption have been distinguished. We present a case of obstetric trauma in a primiparous woman aged 25 years with grade 3 perineal tear. The injury was repaired within 2 hours of delivery. The muscles were sutured using the overlap method with good functional and cosmetic outcomes. The patient reported no symptoms of incontinence in the following weeks after the injury, the anus was compact. A follow-up proctological examination showed normal sphincter tone and function. We would like to emphasise the importance of regular training in practical proctological knowledge. The ability to repair such a challenging injury requires continuous proctological practice. Grade 3-4 perineal injuries are relatively rare, most commonly managed by obstetric gynaecologists. Therefore, it is often impossible to acquire skills in this area as part of daily surgical practice.