bluuebunny/crossref_metadata_2025 huggingface dataset:
Delayed Bladder Perforation Related to Immediate Single Dose Intravesical Doxorubicin Instillation After TURBT: A Case Report and Literature Review
Authors: Alrabadi Adel , Abuhamad Mohannad , Mansi Hammam , Alhamss Sohaib , Bustami Nadwa , Al Demour Saddam , Al-Abbadi Mousa A
Published: January 2021

Introduction:

Intravesical chemotherapy instillation immediately after tumor resection is a well-known practice in the management of non-muscle invasive bladder cancer. Despite being largely well tolerated in most cases, it is not devoid of severe and life-threatening complications.

Case Presentation:

We present an unusual case of bladder perforation that happened 2 weeks after bladder tumor resection. The patient had received single dose intra-vesical instillation of doxorubicin after TUR-BT. Conservative managements failed to achieve bladder healing; as a result, open surgical repair was performed. To the best of our knowledge, this is the first reported case of bladder perforation after intra-vesical doxorubicin instillation.

Conclusion:

The occurrence of such a rare serious complication in a mostly safe intervention must be taken into consideration. A high index of suspicion, timely management, and proceeding to more invasive surgical treatments when necessary are cornerstones in the management and preserving the bladder.
Vascular comorbidity is associated with lower brain volumes and lower neuroperformance in a large multiple sclerosis cohort
Authors: Fitzgerald Kathryn C , Damian Anne , Conway Devon , Mowry Ellen M
Published: January 2021

Objective:

The objective of this study is to assess the association between vascular comorbidity burden with clinical and imaging features of disease burden in a large population of people with multiple sclerosis (MS).

Methods:

We included participants from the MS Partners Advancing Technology Health Solutions (MS PATHS) cohort. We evaluated if vascular comorbidities (diabetes, hypertension, and dyslipidemia) or a composite sum of comorbidities was associated with MS characteristics, including objective neurologic function assessments and quantitative brain magnetic resonance imaging (MRI) measurements in propensity score–weighted models.

Results:

In total, 11,506 participants (6409 (55%) with brain MRI) were included. Individuals with 2+ vascular comorbidities had slower walking speed (standard deviation (SD) = −0.49; 95% confidence interval (CI) = −0.78, −0.19; p = 0.001), slower manual dexterity (SD = −0.41; 95% CI = −0.57, −0.26; p < 0.0001), and fewer correct scores on cognitive processing speed (SD = −0.11; 95% CI = −0.20, −0.02; p = 0.02) versus those with no comorbidities. Those with 2+ had lower brain parenchymal (−0.41%, 95% CI = −0.64, −0.17) and gray matter fractions (−0.30%, 95% CI = −0.49, −0.10), including reduced cortical (−10.10 mL, 95% CI = −15.42, −4.78) and deep (−0.44 mL, 95% CI = −0.84, −0.04) gray matter volumes versus those with no comorbidity.

Conclusion:

Increased vascular comorbidity burden was associated with clinical and imaging markers of neurologic dysfunction and neurodegeneration in MS. Strategies to optimize comorbidity management in people with MS are warranted.
Situational selves of online identity and rationality in choosing – More examples of the college students’ online identity in China
Authors: Qin Yue , Lowe John
Published: January 2021

The Internet has provided a new context for the exploration of the concept of identity. Different identities were expressed on different online settings, which indicates the feature of ‘situational selves’ of online identities. By comparing the differences among WeChat identity, Weibo identity and offline identity, more examples were introduced not only to explain ‘situational selves’, but also the ‘rationality’ in choosing among different online identities.
Digital placemaking as survival tactics: Sub-Saharan migrants’ videos at the Moroccan–Spanish border
Authors: Labayen Miguel Fernández , Gutierrez Irene
Published: January 2021

This article examines the use of digital media by irregular migrants in their preparation to cross the Moroccan–Spanish border. Based on long-term exploratory research that includes active participation and in-depth interviews, we analyse the videos produced by sub-Saharan young males while they live in the settlements near Ceuta. By focusing on processes of self-representation and border crossing, we highlight the role of digital media as it embodies a liminal physical experience against the violence applied by the Moroccan border security forces and the surveillance systems implemented by the Spanish Guardia Civil. Departing from recent contributions to digital migration studies, this article develops the concept of digital placemaking as an assemblage of discourses and spatial practices that serve opposite interests and generate an extremely violent confrontation through the use and control of borderspace. Therefore, we claim that the migrants’ placemaking strategies can be understood as mobile counter-discourses against border control. In this sense, the physical and digital activities of the migrants in the settlements are examples of what we call tactical placemaking, insofar as they become ways to stay alive and link their persons and futures to discussions about access to place and its consequences. To examine the migrants’ spatial tactics and their social meaning, first we will offer a brief infrastructural and historiographical account of the Moroccan–Spanish border in Ceuta. Second, we will explain our methodological perspective to shed light on the modes that placemaking experiences are created and circulated among migrants during and after their stay at the settlements. Finally, we will study the self-recordings shot in the clandestine camps of the forest in Fnideq and the border of Ceuta and consider how these videos materialize legal, cultural and physical imaginaries on migration while they simultaneously disrupt official attempts at controlling placemaking.
A cost-minimisation analysis comparing alternative telemedicine screening approaches for retinopathy of prematurity
Authors: Kim Emmanuel , Nguyen Kim-Huong , Donovan Tim , Edirippulige Sisira , Armfield Nigel R
Published: January 2021

Introduction

Screening for retinopathy of prematurity (ROP) is an important procedure in the prevention of blindness in high-risk preterm infants. In the regionalised healthcare system of Queensland (Australia), outside of the major centres, some preterm infants are cared for in special care nurseries (SCNs). When necessary, infants in these nurseries who are at risk of ROP are transferred to a tertiary hospital for screening by paediatric ophthalmologists. The transport of preterm infants for eye examinations adds risk and incurs significant costs to the health system. Using a cost-minimisation approach, we aimed to compare the costs of the current ROP screening practice with two alternative telemedicine approaches.

Methods

We constructed a decision analytic model to estimate costs from a health service perspective with a five-year analysis horizon; activity data from a tertiary ROP screening service were used to inform the models. The three models assessed were: (a) a digital retinal photography (DRP)-equipped travelling nurse, (b) equipping SCNs with DRP, and providing training to local nurses, and (c) current practice of infant transfer. In all cases, the tertiary centre provides specialist ophthalmologic review.

Results

Of the three models, we estimated the most expensive option to be equipping SCNs with DRP and providing training to local nurses (AUD$4114/infant). We found that the current practice of transferring infants was the second most expensive (AUD$1021/infant). The most economical model was the specialist nurse travelling to each SCN with a portable DRP (AUD$363/infant). A sensitivity analysis, which assessed uncertainty and variability around the cost estimates, found that the ranking for the expected costs of the alternative models of care did not change.

Discussion

This is the first economic and cost-minimisation analysis in Australia to compare the costs of the current screening programme with two alternative telemedicine approaches for screening ROP. Telemedicine programmes that facilitate non-physician screening may improve the cost efficiency of the health system while maintaining the health outcomes for children, and reducing the risk associated with infant transport.
Home-based music therapy for children with developmental disorders during the COVID-19 pandemic
Authors: Bompard Sarah , Liuzzi Tommaso , Staccioli Susanna , D’Arienzo Fiammetta , Khosravi Sahereh , Giuliani Roberto , Castelli Enrico
Published: January 2021

Introduction

During the COVID-19 pandemic, children with neurodevelopmental disabilities could not attend their usual rehabilitation therapies, with a consequent reduced support of developmental process and risk of worsening of their clinical conditions.

Methods

We prospectively enrolled 14 children with developmental delay, who had already tried a personalised music therapy (Euterpe method). We included them in a 12-day programme of home-based music therapy. The children and their parents were investigated using the Sleep Disturbance Scale for Children and the Parent Stress Index-Short Form.

Results

Fourteen children started the intervention, while only 12 children completed all the planned home sessions and assessments. We observed a significant improvement in children’s sleep quality and a reduction of parental distress.

Discussion

The significant improvements in parental distress and sleep quality must be considered important achievements for the quality of life of a child and their family. Home-based music therapy can provide a feasible approach to improving sleep and parent’s stress for children with developmental disorders.
Internal carotid artery aneurysm presenting as diplopia via telemedicine during COVID-19
Authors: Baxter Sally L , Kuo David E , Robbins Shira L
Published: January 2021

A patient presented with acute onset of double vision during the start of the COVID-19 pandemic when elective medical care was restricted. Initially declining an in-person evaluation, she was examined using a telehealth video visit, incorporating multiple technological modalities to ascertain ophthalmic examination elements. Her findings prompted emergent neuroimaging, revealing a giant internal carotid artery aneurysm, which was successfully embolized to prevent debilitating and possibly fatal intracranial haemorrhage. This case report illustrates the successful use of telemedicine and remote patient data acquisition to make a life-saving diagnosis.
Stress, coping, and preventing contagion during the SARS-COV2 epidemic in a sample of Mexican adults
Authors: Javier Rosas-Santiago Francisco , Roberto Lagunes-Córdoba
Published: January 2021

Given the lack of an effective treatment for COVID-19, it is essential to explore the psychological variables involved in the development and maintenance of preventive behaviors during the current epidemic. In this study, we analyze the predictive value of perceived stress (measured with the Perceived Stress Scale) and coping styles (measured with the Extreme Risks Coping Scale) for adhering to infection prevention behavior in a sample of 1132 Mexican adults aged between 18 and 84. A logistic regression analysis showed that Active Coping and Cognition-Focused Coping, in addition to age and being a student, proved to be predictors of adhering to SARS COV2 preventive behaviors ( R2 = 0.282). The findings from this study can be used to design strategies to promote potentially effective epidemic mitigation behaviors.
‘You’re a populist! No, you are a populist!’: The rhetorical analysis of a popular insult in the United Kingdom, 1970–2018
Authors: Casiraghi Matteo CM
Published: January 2021

This article focuses on discourses on populism, presenting a case study on the United Kingdom. Analysing all references to populism in the British Parliament from 1970 to 2018, this article provides a framework to think about rhetoric and populism, a method to investigate political attitudes, and insights about the debate on populism in the United Kingdom. Results show that from the 1970s to the 1990s politicians interpret populism in demagogical terms and most often refer to the category of the political role of ‘the people’. More recently, negative references and personal attacks increase, and politicians refer to different categories. Moreover, the analysis shows how British politicians employ epideictic and forensic rhetorical strategies more often when debating about populism, whereas deliberative strategies rarely emerge. Finally, the investigation over the 2015–2018 period shows that government membership, a distant election, and a right-wing party membership increase the likelihood of rhetorical positive interpretations of populism.
A multi-layer moving plate method for dynamic analysis of viscoelastically connected double-plate systems subjected to moving loads
Authors: Cao Tan Ngoc Than , Reddy JN , Lieu Qui X , Nguyen Xuan Vu , Luong Van Hai
Published: January 2021

This article aims to firstly introduce a computational approach, named multi-layer moving plate method (MMPM), to dynamic analysis of viscoelastically connected infinitely long double-plate systems subjected to moving loads. The Reissner-Mindlin plate theory is utilized to describe the displacement field through the thickness of each plate, whilst quadratic serendipity shape functions are employed to represent unknown fields in finite element analyses (FEAs). The governing equations of motion of connected double-plate system are established in a moving coordinate system attached to the moving load. As a consequence, the paradigm can absolutely eradicate the update process of force vector since the applied load is taken into account as “stationary” in its coordinate system. First, several numerical examples for static, free vibration and dynamic analyses are exhibited to verify the accuracy of the proposed MMPM. Then, the influences of various parameters such as load’s velocity, damping coefficient, stiffness coefficient, and plate thickness on the dynamic responses of double-plate system are examined in great detail.
Health-system equity, egalitarian democracy and COVID-19 outcomes: An empirical analysis
Authors: Vadlamannati Krishna Chaitanya , Cooray Arusha , de Soysa Indra
Published: January 2021

Aims:

The COVID-19 pandemic has led to a spate of studies showing a close connection between inequitable access to health care, welfare services and adverse outcomes from the pandemic. Others have argued that democratic governments have generally failed relative to more autocratic ones, simply because autocrats can make the hard choices required for stemming the spread of viruses. We address this question by asking whether more ‘egalitarian’ forms of democracy matter, given that they contain more equitable health-care access and societal infrastructure, such as social capital and trust.

Methods:

We use standard regression techniques, including instrumental variables analysis addressing endogeneity on COVID-19 testing and deaths data as of the end of May and beginning of September. We use novel data from the Varieties of Democracy Project on health-system equity and egalitarian democracy.

Results:

Our results suggest that more equitable access to health care increases testing rates and lowers the death rate from COVID-19. Broader egalitarian governance, measured as egalitarian democracy, however, shows the opposite effect. Thus, factors associated with health-care capacity to reach and treat matter more than broader societal factors associated with social capital and trust. The results are robust to alternative testing procedures, including instrumental variable technique for addressing potential endogeneity.

Conclusions:

Despite a great deal of public health focus on how equitable governance helps fight the adverse effects of so-called neoliberal pandemics, we find that broadly egalitarian factors have had the opposite effect on fighting COVID-19, especially when an equitable health system has been taken into account. Fighting disease, thus, might be more about the capacity of health systems rather than societal factors, such as trust in government and social capital.
Admins, mods, and benevolent dictators for life: The implicit feudalism of online communities
Authors: Schneider Nathan
Published: January 2021

Online platforms train users to interact with each other through certain widespread interface designs. This article argues that an “implicit feudalism” informs the available options for community management on the dominant platforms for online communities. It is a pattern that grants user-administrators absolutist reign over their fiefdoms, with competition among them as the primary mechanism for quality control, typically under rules set by platform companies. Implicit feudalism emerged from technical conditions dating to early online networks. In light of alternative management mechanisms with more democratic features, it becomes all the more clear that implicit feudalism is not a necessary condition.
Safe operation of dual-fuel engines using constrained stochastic control
Authors: Guardiola Carlos , Pla Benjamín , Bares Pau , Barbier Alvin
Published: January 2021

Premixed combustion strategies have the potential to achieve high thermal efficiency and to lower the engine-out emissions such as NOx. However, the combustion is initiated at several kernels which create high pressure gradients inside the cylinder. Similarly to knock in spark ignition engines, these gradients might be responsible of important pressure oscillations with a harmful potential for the engine. This work aims to analyze the in-cylinder pressure oscillations in a dual-fuel combustion engine and to determine the feedback variables, control actuators, and control approach for a safe engine operation. Three combustion modes were examined: fully, highly, and partially premixed, and three indexes were analyzed to characterize the safe operation of the engine: the maximum pressure rise rate, the ringing intensity, and the maximum amplitude of pressure oscillations (MAPO). Results show that operation constraints exclusively based on indicators such as the pressure rise rate are not sufficient for a proper limitation of the in-cylinder pressure oscillations. This paper explores the use of a knock-like controller for maintaining the resonance index magnitude under a predefined limit where the gasoline fraction and the main injection timing were selected as control variables. The proposed strategy shows the ability to maintain the percentage of cycles exceeding the specified limit at a desired threshold at each combustion mode in all the cylinders.
Improved damage detection in Pelton turbines using optimized condition indicators and data-driven techniques
Authors: Zhao Weiqiang , Egusquiza Mònica , Estevez Aida , Presas Alexandre , Valero Carme , Valentín David , Egusquiza Eduard
Published: January 2021

The health condition of hydraulic turbines is one of the most critical factors for the operation safety and financial benefits of a hydro power plant. After the massive entrance of intermittent renewable energies, hydropower units have to regulate their output much more frequently for the balancing of the power grid. Under these conditions, the components of the machine have to withstand harsher excitation forces, which are more likely to produce damage and eventual failure in the turbines. To ensure the reliability of these machines, improved condition monitoring techniques are increasingly demanded.

In this article, the feasibility of upgrading condition monitoring of Pelton turbines using novel vibration indicators and data-driven techniques is discussed. The new indicators are selected after performing a detailed analysis of the dynamic behavior of the turbine using numerical models and field measurements. After that, factor analysis is carried out in order to assess which are the most informative indicators and to reduce the dimension of the input data.

For the validation of the proposed method, monitoring data from an actual Pelton turbine that suffered from an important fatigue failure due to a crack propagation on the buckets have been used. The novel condition indicators as well as classical indicators based on the spectrum and harmonics levels have been obtained while the machine was in good operation, during different stages of damage and after repair. All of these have been used to train an artificial neural network model in order to predict the evolution of the crack until failure occurs. The results show that using the improved monitoring methodology enhances the ability to predict the appearance of damage in comparison to typical condition indicators.
Apolipoprotein A1 and Low-Density Lipoprotein as Risk Factors for Intraocular Metastases in Postmenopausal Breast Cancer
Authors: Li Biao , Liu Yao , Yuan Qing , Lin Qi , Shi Wen-Qing , Zhu Pei-Wen , Min You-Lan , Ge Qian-Min , Shao Yi
Published: January 2021

Background:

The outcomes of patients with postmenopausal breast cancer(PBC) can be improved through the early detection of intraocular metastases(IOMs). In this study, we investigated patients with PBC, and compared those with IOMs with those with non-intraocular metastases(NIOMs) in terms of blood lipid levels, and then differentiated the risk factors associated with IOMs.

Methods:

Student’s t-test and a chi-square test were used to discriminate between the IOMs and NIOMs groups. After establishing a Poisson regression model to analyze risk factors, we plotted receiver operating characteristic curves(ROC) to assess the quality of risk factors predicting IOMs.

Results:

The incidence of IOMs in PBC was 1.16%. There was no significant difference in terms of histopathology between the 2 groups. The levels of total cholesterol (TC), apolipoprotein A1(APOA1) and low-density lipoprotein(LDL) in IOMs were significantly lower than in NIOMs groups. Poisson regression suggested that low levels of APOA1 and LDL were risk factors for IOMs (P = 0.002 and P < 0.001, respectively). ROC curve analysis demonstrated that the cut-off values of APOA1 and LDL were 1.025 g/L and 2.415 mmol/L. The highest prediction accuracy for IOMs involved the combination of APOA1 and LDL (AUC = 0.881, P < 0.001).

Conclusion:

Our research demonstrates that low levels of APOA1 and LDL efficiently predict IOMs in PBC as risk factors, and the combination of APOA1 and LDL was more predictive than single factors.
Work–Life Intersections in Peacebuilding, Development, and Humanitarian Aid
Authors: Van Duzer Nate
Published: January 2021

Through a literature review and a qualitative study, this essay examines how experienced professionals in the fields of peacebuilding, development, and humanitarian aid view their vocation and how they conduct themselves at the intersections of work and life. Combining reflections on work–life balance and literature specific to the three fields mentioned above, it offers a theoretical framework for considering how the management of these intersections affects both personal life satisfaction and work outcomes. Individuals in these fields face specific pressures that may contribute to negative spillover from work to nonwork life. These pressures can cause stress and adverse mental health, leading to decreased personal satisfaction and impaired reflective practice. These outcomes can be mitigated by several factors including organisational or social support, work–life enrichment practices, healthy boundaries, and/or strong nonwork identities. A qualitative study of 20 professionals in these fields helps illustrate some of these dynamics.
Constraint-Induced Movement Therapy Promotes Neural Remodeling and Functional Reorganization by Overcoming Nogo-A/NgR/RhoA/ROCK Signals in Hemiplegic Cerebral Palsy Mice
Authors: Liu Li-Ru , Wang Yu-Xin , He Lu , Xu Yun-Xian , Huang Jing-Yu , Peng Ting-Ting , Yang Xu-Bo , Pan Jing , Tang Hong-Mei , Xu Kai-Shou
Published: January 2021

Background. Little is known about the induction of functional and brain structural reorganization in hemiplegic cerebral palsy (HCP) by constraint-induced movement therapy (CIMT). Objective. We aimed to explore the specific molecular mechanism of functional and structural plasticity related to CIMT in HCP. Methods. The mice were divided into a control group and HCP groups with different interventions (unconstraint-induced movement therapy [UNCIMT], CIMT or siRNA-Nogo-A [SN] treatment): the HCP, HCP+UNCIMT, HCP+CIMT, HCP+SN, and HCP+SN+CIMT groups. Rotarod and front-limb suspension tests, immunohistochemistry, Golgi-Cox staining, transmission electron microscopy, and Western blot analyses were applied to measure motor function, neurons and neurofilament density, dendrites/axon areas, myelin integrity, and Nogo-A/NgR/RhoA/ROCK expression in the motor cortex. Results. The mice in the HCP+CIMT group had better motor function, greater neurons and neurofilament density, dendrites/axon areas, myelin integrity, and lower Nogo-A/NgR/RhoA/ROCK expression in the motor cortex than the HCP and HCP+UNCIMT groups ( P < .05). Moreover, the expression of Nogo-A/NgR/RhoA/ROCK, the improvement of neural remodeling and motor function of mice in the HCP+SN group were similar to those in the HCP+CIMT group ( P > .05). The neural remodeling and motor function of the HCP+SN+CIMT group were significantly greater than those in the HCP+SN and HCP+CIMT groups ( P < .05). Motor function were positively correlated with the density of neurons ( r = 0.450 and 0.309, respectively; P < .05) and neurofilament ( r = 0.717 and 0.567, respectively; P < .05). Conclusions. CIMT might promote the remodeling of neurons, neurofilament, dendrites/axon areas, and myelin in the motor cortex by partially inhibiting the Nogo-A/NgR/RhoA/ROCK pathway, thereby promoting the improvement of motor function in HCP mice.
Minimally Invasive Left Ventricular Assist Device Insertion Facilitates Subsequent Heart Transplant
Authors: Rabin Joseph , Ziegler Luke A. , Cipriano Sarah , Madathil Ronson J. , Feller Erika D. , Sorensen Erik N. , Griffith Bartley P. , Kaczorowski David J.
Published: January 2021

Objective

We have observed that minimally invasive left ventricular assist device (LVAD) insertion leads to more facile re-entry and easier cardiac transplantation. We hypothesize minimally invasive LVAD implantation results in improved outcomes at the time of subsequent heart transplant.

Methods

All adults undergoing cardiac transplantation between October 2015 and March 2019 at our institution were retrospectively reviewed. Those bridged to transplantation with a HeartWare HVAD were identified and divided into 2 cohorts based upon the surgical approach: those who underwent HVAD placement by conventional sternotomy versus minimally invasive insertion via lateral thoracotomy and hemisternotomy (LTHS). Patient demographics, as well as perioperative transplant outcomes, including survival, length of stay (LOS), blood utilization, ischemic time, bypass time, and postoperative extracorporeal membrane oxygenation (ECMO) were compared between cohorts.

Results

Forty-two patients were bridged to heart transplant with a HVAD implanted via either sternotomy ( n = 22) or LTHS technique ( n = 20). Demographics were similar between groups. There was 1 predischarge death in the sternotomy group and none in the LTHS group. Body surface area, cardiopulmonary bypass time, ischemic time, ECMO utilization, and reoperation for bleeding were similar. Red blood cell units transfused were significantly lower in the LTHS cohort (3.0 [1.0-5.0] vs 6.0 [2.5-10.0] P = 0.046). The LTHS cohort had a significantly shorter hospital LOS (12.0 [11.0-28.0] vs 22.5 [15.7-41.7] P = 0.022) with a trend toward shorter intensive care unit LOS (6.0 [5.0-10.5] vs 11.0 [6.0-21.5] days P = 0.057).

Conclusions

Minimally invasive HVAD implantation improves outcomes at subsequent heart transplantation, resulting in shorter LOS and less red cell transfusion. Larger multi-institutional studies are necessary to validate these findings.
Using National Data to Inform Our Understanding of Family and Intimate Partner Violence Victimization: A Review of a Decade of Innovation
Authors: Addington Lynn A. , Lauritsen Janet L.
Published: January 2021

This review summarizes developments over the past decade in national data sources that can further our understanding of intimate partner and family violence. Particular attention is given to recent improvements in the National Crime Victimization Survey and Uniform Crime Reporting Program’s National Incident-Based Reporting System as well as to features of the National Intimate Partner and Sexual Violence Survey. Over the past 10 years, these data sources have broadened their collection in areas such as victim demographics, disclosure and access to services. This information can support the research necessary to better respond to victims of intimate partner and family violence.
Age and discharge modified Rankin score are associated with 90-Day functional outcome after basilar artery occlusion treated with endovascular therapy
Authors: Karamchandani Rahul R , Strong Dale , Rhoten Jeremy B , Prasad Tanushree , Selig Jacob , Defilipp Gary , Asimos Andrew W
Published: January 2021

Introduction

Prognostic factors for functional outcome after basilar artery occlusion (BAO) treated with modern endovascular therapy (EVT) are sparse. We investigated the association between clinical characteristics, readily available imaging variables, and outcome in BAO patients treated with EVT.

Methods

Retrospective analysis from a large healthcare system’s prospectively collected code stroke registry of acute BAO patients treated with EVT between January 2017–January 2020. The primary outcome measure was a favorable 90-day modified Rankin score (mRS) of 0-2.

Results

65 patients (median age 67 years, 57% male, median NIHSS 16) met the study inclusion criteria. Thrombolysis in Cerebral Infarction (TICI) 2 b-3 revascularization was achieved in 57/65 patients (88%) with a median time to revascularization of 445 minutes [IQR 302-840]. Ninety-day good outcome was seen in 35% (23/65) of patients. In a univariate analysis, age, history of ischemic stroke, baseline NIHSS, BAO site, and discharge mRS were associated with significant differences between the good and poor outcome groups. A multivariable logistic regression analysis demonstrated an independent association with 90-day good outcome and younger age (per 1-year, OR 0.79, 95% CI 0.64, 0.98) and good discharge mRS (0-2) (OR > 999.99, 95% CI 13.26, > 999.99).

Conclusions

Patients presenting with an acute BAO treated with modern EVT have a good 90-day outcome in over one-third of cases. Age and discharge mRS are independently associated with good 90-day outcome. Additional studies may focus on factors that can enhance discharge function after BAO, a novel prognostic indicator for favorable 90-day outcome in our study.
Leading through COVID-19: New Zealand secondary principals describe their reality
Authors: Thornton Kate
Published: January 2021

School principals were required to engage in crisis leadership throughout New Zealand’s first seven-week COVID-19 lockdown in March 2020. Eighteen school principals from a range of secondary schools were interviewed about their experiences. The challenges they faced included preparing students and teachers for online teaching and learning for an unknown length of time, supporting student and staff wellbeing, and communicating clearly and compassionately to all stakeholder groups. Their opportunities related to strengthening digital teaching and learning, distributing leadership and resetting direction. This study identifies a number of implications for future crisis leadership practice including: preparing, attending to wellbeing, communicating effectively, leading collaboratively and taking opportunities.
So Useful as a Good Theory? The Practicality Crisis in (Social) Psychological Theory
Authors: Berkman Elliot T. , Wilson Sylas M.
Published: January 2021

Practicality was a valued attribute of academic psychological theory during its initial decades, but usefulness has since faded in importance to the field. Theories are now evaluated mainly on their ability to account for decontextualized laboratory data and not their ability to help solve societal problems. With laudable exceptions in the clinical, intergroup, and health domains, most psychological theories have little relevance to people’s everyday lives, poor accessibility to policymakers, or even applicability to the work of other academics who are better positioned to translate the theories to the practical realm. We refer to the lack of relevance, accessibility, and applicability of psychological theory to the rest of society as the practicality crisis. The practicality crisis harms the field in its ability to attract the next generation of scholars and maintain viability at the national level. We describe practical theory and illustrate its use in the field of self-regulation. Psychological theory is historically and scientifically well positioned to become useful should scholars in the field decide to value practicality. We offer a set of incentives to encourage the return of social psychology to the Lewinian vision of a useful science that speaks to pressing social issues.
Residential Mobility and Trust: The Moderating Role of Cognitive Need for Closure
Authors: Zhao Na , Xu Kaiqiang , Sun Ling
Published: January 2021

This study examined the link between residential mobility and interpersonal trust building. Study 1 revealed a negative association between residential mobility and trust by measuring personal residential-mobility history. Study 2 demonstrated that participants who were momentarily primed with mobility showed a lower investment than participants in the control group in a trust game. The results of Study 3 showed that need for closure moderated the link between residential mobility and trust-building intention. Specifically, lower need-for-closure people had a significantly lower trust tendency in the mobility group than in the stable group. These findings illuminate the underlying influence of need for closure in the link between residential mobility and trust.
An Atypical Case of Neurosyphilis in a Patient With HIV: A Case Report
Authors: Chernyak Elizabeth , Shi Hang , Theodore Deborah A. , Thakur Kiran T.
Published: January 2021

Epidemiological trends have demonstrated re-emergence of neurosyphilis in the twenty-first century. As prevalence rises in clinical practice, neurosyphilis must be considered in the differential diagnosis even if initial diagnostic workup is unrevealing, especially in patients with human immunodeficiency virus (HIV). Co-infection of neurosyphilis and HIV can result in atypical presentations. In this report, we discuss a challenging diagnosis of neurosyphilis in a man with HIV who presented with atypical imaging findings and initially negative cerebrospinal fluid (CSF) nontreponemal testing. Our patient underwent repeated CSF evaluation and a comprehensive diagnostic workup, including brain biopsy, to arrive at the appropriate diagnosis. He received antibiotic treatment with excellent outcome. We review typical imaging features of neurosyphilis and highlight other neurological diseases that may mimic these radiographic findings. We discuss CSF testing and interpretation in this high-risk patient population.
Osteochondral Lesions of the Talus: A Review on Talus Osteochondral Injuries, Including Osteochondritis Dissecans
Authors: Bruns Juergen , Habermann Christian , Werner Mathias
Published: January 2021

This is a review on talus osteochondritis dissecans and talus osteochondral lesions. A majority of the osteochondral lesions are associated with trauma while the cause of pure osteochondritis dissecans is still much discussed with a possible cause being repetitive microtraumas associated with vascular disturbances causing subchondral bone necrosis and disability. Symptomatic nondisplaced osteochondral lesions can often be treated conservatively in children and adolescents while such treatment is less successful in adults. Surgical treatment is indicated when there is an unstable cartilage fragment. There are a large number of different operative technique options with no number one technique to be recommended. Most techniques have been presented in level II to IV studies with a low number of patients with short follow ups and few randomized comparisons exist. The actual situation in treating osteochondral lesions in the ankle is presented and discussed.
Beyond geopoetics: For hybrid texts
Authors: Cresswell Tim
Published: January 2021

This commentary responds to Eric Magrane’s welcome focus on the possibilities of ‘climate geopoetics’ as a way of accessing and thinking environmental crisis differently. It explores the problem of approaching the general through the particular and the affordances that poetry provides in making this leap. In addition, it questions the particular veneration of the poet and poem and, building on the experiments of both poets and academics, argues for the embrace of hybrid forms that transcends the poetry/non-poetry divide.
Walking Through Twitter: Sampling a Language-Based Follow Network of Influential Twitter Accounts
Authors: Münch Felix Victor , Thies Ben , Puschmann Cornelius , Bruns Axel
Published: January 2021

Twitter continuously tightens the access to its data via the publicly accessible, cost-free standard APIs. This especially applies to the follow network. In light of this, we successfully modified a network sampling method to work efficiently with the Twitter standard API in order to retrieve the most central and influential accounts of a language-based Twitter follow network: the German Twittersphere. We provide evidence that the method is able to approximate a set of the top 1% to 10% of influential accounts in the German Twittersphere in terms of activity, follower numbers, coverage, and reach. Furthermore, we demonstrate the usefulness of these data by presenting the first overview of topical communities within the German Twittersphere and their network structure. The presented data mining method opens up further avenues of enquiry, such as the collection and comparison of language-based Twitterspheres other than the German one, its further development for the collection of follow networks around certain topics or accounts of interest, and its application to other online social networks and platforms in conjunction with concepts such as agenda setting and opinion leadership.
Stock Market Liquidity: A Literature Review
Authors: Naik Priyanka , Reddy Y. V.
Published: January 2021

The purpose of this study is to identify the key aspects that have been studied in the area of stock market liquidity, accumulate their important findings, and also provide a quantitative categorization of reviewed literature that will facilitate in conducting further research. The study analyzes relevant research papers published after the global financial crisis of 2008 and finds that measurement of liquidity, factors influencing liquidity, the relationship between market liquidity and expected return, and market liquidity risk and its relationship with expected returns have been explored in the context of the stock market liquidity. Among these, the factors influencing liquidity have been prominently researched in the reviewed studies. The study concludes that the identified areas can be potentially researched concerning the emerging markets by considering the multidimensional quality of market liquidity. Also, the inter-linkages between the liquidity of emerging markets with that of the global stock markets can be further evaluated.
Evidence of Inflated Prediction Performance: A Commentary on Machine Learning and Suicide Research
Authors: Jacobucci Ross , Littlefield Andrew K. , Millner Alexander J. , Kleiman Evan M. , Steinley Douglas
Published: January 2021

The use of machine learning is increasing in clinical psychology, yet it is unclear whether these approaches enhance the prediction of clinical outcomes. Several studies show that machine-learning algorithms outperform traditional linear models. However, many studies that have found such an advantage use the same algorithm, random forests with the optimism-corrected bootstrap, for internal validation. Through both a simulation and empirical example, we demonstrate that the pairing of nonlinear, flexible machine-learning approaches, such as random forests with the optimism-corrected bootstrap, provide highly inflated prediction estimates. We find no advantage for properly validated machine-learning models over linear models.
Low Rate of Return to Preinjury Tegner Activity Level Among Recreational Athletes: Results at 1 Year After Primary ACL Reconstruction
Authors: Kim Su-Hyun , Lee Ja-Woon , Kim Sang-Gyun , Cho Hyun-Woo , Bae Ji-Hoon
Published: January 2021

Background:

There is limited information about the functional recovery and rate of return to preinjury levels of sports among recreational athletes after anterior cruciate ligament reconstruction (ACLR).

Purpose:

To investigate the recovery of quadriceps or hamstring strength, assess functional performance, and determine the rate of return to preinjury sports levels among recreational athletes at 1 year after ACLR.

Study Design:

Cohort study; Level of evidence, 3.

Methods:

A total of 91 recreational-level athletes who underwent anatomic single-bundle ACLR were enrolled. We evaluated the limb symmetry index (LSI) of the quadriceps and hamstring peak torque strength at 60°, in addition to hop test performance (single-leg, triple, crossover, and 6-m timed), patient-reported outcomes, and pre- versus postoperative Tegner activity levels. Outcomes were compared between younger (age <25 years) and older patients (age ≥25 years).

Results:

There were 48 patients in the younger group and 43 patients in the older group. At 1-year follow-up, the overall LSIs for quadriceps strength and hamstring strength were 77% and 86%, respectively, and the LSIs of the hop tests were 79% for single-leg, 81% for triple, 84% for crossover, and 85% for 6-m timed hop. Overall, only 24% patients returned to their preinjury Tegner level, and only 8% of patients met the criteria for return to pivoting, cutting, and jumping sports. At 1-year follow-up, the younger group showed significantly more quadriceps strength than the older group (85% vs 64%; P = .0001), better single, triple, crossover, and 6-m timed hop test results (85% vs 69%, P = .003; 84% vs 75%, P = .046; 91% vs. 74%, P < .001; and 91% vs 76%, P = .003, respectively), higher Lysholm score (87 vs 74; P < 0.001) and International Knee Document Committee score (82 vs 66; P < .001), and a higher rate of return to preinjury Tegner level (35% vs 12%; P = .009).

Conclusion:

Only 24% of patients returned to the preinjury Tegner level at 1 year after ACLR (35% younger group vs 12% older group; P = .009). This information might be helpful in setting realistic expectations for recreational athletes after surgery.
Promoting Problem Solving About Health Management: A Mixed-Methods Pilot Evaluation of a Digital Health Intervention for Older Adults With Pre-Frailty and Frailty
Authors: Chen Annie T. , Chu Frances , Teng Andrew K. , Han Soojeong , Lin Shih-Yin , Demiris George , Zaslavsky Oleg
Published: January 2021

Background: There is a need for interventions to promote health management of older adults with pre-frailty and frailty. Technology poses promising solutions, but questions exist about effective delivery. Objectives: We present the results of a mixed-methods pilot evaluation of Virtual Online Communities for Older Adults (VOCALE), an 8-week intervention conducted in the northwestern United States, in which participants shared health-related experiences and applied problem solving skills in a Facebook group. Methods: We performed a mixed-methods process evaluation, integrating quantitative and qualitative data, to characterize the intervention and its effects. We focus on four areas: health-related measures (health literacy and self-efficacy), participation, problem solving skills enacted, and subjective feedback. Results: Eight older adults with pre-frailty and frailty (age = 82.7 ± 6.6 years) completed the study. There was an upward trend in health literacy and health self-efficacy post-intervention. Participants posted at least two times per week. Content analysis of 210 posts showed participants were able to apply the problem solving skills taught, and exit interviews showed participants’ increased awareness of the need to manage health, and enjoyment in learning about others. Conclusion: This mixed-methods evaluation provides insight into feasibility and design considerations for online interventions to promote health management among vulnerable older adults.
Myositis Ossificans Traumatica of the Temporal Muscle Treated by Bilateral Coronoidectomy and Aggressive Physiotherapy: A Case Report
Authors: Pereira Juliana Reuter , Bachesk Andressa Bolognesi , Pierri Ricardo Augusto Gonçalves , Iwaki Filho Liogi
Published: January 2021

Myositis Ossificans Traumatica (MOT) is a rare condition that affects soft tissues after a trauma and hardly affects the mastication muscles. The occurrence in the temporal muscle is uncommon, and trismus is the most prevalent symptom. The diagnosis of the pathology is sufficiently obtained through the collection of clinical history, physical and imaging exams. Differential diagnosis is important mainly to rule out more aggressive diseases, such as osteosarcoma. Treatment becomes more invasive as the ossification matures, and resection of structures adjacent to the tumor, such as coronoidectomy, is well indicated for promoting good results on the mouth opening amplitude. However, to maintain this amplitude, aggressive myofunctional therapy is required. Nevertheless, the literature has no well-defined protocol for this physiotherapy. Therefore, this article reports a rare case of MOT in the temporal muscle that was treated conservatively, with bilateral coronoidectomy and mouth opening physiotherapy, and obtained a satisfactory result. Consequently, it also presents a suggestion of a postoperative physiotherapy protocol.
The effect of soil nonlinearity on high-frequency spectral decay and implications for site response analysis
Authors: Xu Boqin , Rathje Ellen M
Published: January 2021

This study uses recorded ground motions at soil sites over a range of shaking intensities to investigate the effects of soil nonlinearity on the high-frequency spectral decay, as quantified by the parameter [Formula: see text]. Equivalent-linear site response analyses indicate that [Formula: see text] should increase significantly with increasing shear strain and ground motion intensity due to increases in soil damping. However, using more than 2500 motions from 32 sites, this study shows that [Formula: see text] does not vary systematically with the induced shear strain but instead remains at its small-strain value. This observation indicates that high-frequency components of motion are consistent with small-strain damping, rather than the strain-compatible damping used in site response analysis. It is demonstrated that equivalent-linear site response analyses for large strains can be modified to generate surface motions with more realistic high-frequency content by scaling the predicted surface motion to fit the small-strain [Formula: see text] or by employing frequency-dependent soil properties that account for the frequency dependence of the induced strains.
First-Trimester Diagnosis of Hypoplastic Left Heart Syndrome: A Case Report
Authors: Hildebrand Emily
Published: January 2021

Hypoplastic left heart syndrome (HLHS) comprises a spectrum of left-sided heart anomalies resulting from left outflow or inflow obstruction. Obstruction most often occurs at the levels of the aortic valve and/or mitral valve due to stenosis or atresia. HLHS is a lethal cardiac anomaly if not treated within the first week of life. Knowledge of sonographic features could aid in early detection, which results in better planning and management of pregnancy. This report presents a case in which HLHS was discovered during a routine dating and viability sonogram, performed at 12 weeks’ gestation.