bluuebunny/crossref_metadata_2025 huggingface dataset:
Establishment of ELISA-comparable moderate and high thresholds for anticardiolipin and anti-β2 glycoprotein I chemiluminescent immunoassays according to the 2023 ACR/EULAR APS classification criteria and evaluation of their diagnostic performance
Authors: Žigon Polona , Boštic Nika , Ambrožič Aleš , Rotar Žiga , Blokar Elizabeta , Ogrič Manca , Čučnik Saša
Published: July 2024

Objectives

Recently published 2023 ACR/EULAR APS classification criteria emphasize the importance of quantifying single-, double-, and triple-antiphospholipid antibody positivity, distinguishing between IgG and IgM isotypes, and delineating moderate/high levels of anticardiolipin (aCL) and anti-β2 glycoprotein I (anti-β2GPI) antibodies. We aimed to establish clinically important moderate/high thresholds for aCL and anti-β2GPI IgG/IgM chemiluminescent immunoassays (CLIA), in particular QUANTA Flash, comparable to our in-house ELISAs used for over two decades, and to evaluate their diagnostic performance.

Methods

QUANTA Flash CLIA and in-house ELISAs were used to measure aCL and anti-β2GPI IgG/IgM. Moderate thresholds for QUANTA Flash CLIA were determined using a non-parametric approach, calculating a 99th percentile on serum samples from 139 blood donors, and by mirroring the diagnostic performance of in-house ELISA on 159 patient samples.

Results

Thresholds for QUANTA Flash CLIA achieving diagnostic performance equivalent to in-house ELISAs were 40 CU for moderate and 80 CU for high levels for aCL and anti-β2GPI IgG and IgM. The assays showed good qualitative agreement, ranging from 76.10 to 91.19 %. When considering in-house ELISA results, 14 out of 80 (17.5 %) patients did not fulfill the new ACR/EULAR laboratory classification criteria, while 27 out of 80 (33.8 %) did not when considering QUANTA Flash CLIA results.

Conclusions

We determined moderate and high thresholds for aCL and anti-β2GPI IgG and IgM detected with QUANTA Flash CLIA, aligning with long-established in-house ELISA thresholds. These thresholds are crucial for seamlessly integrating of the new 2023 ACR/EULAR classification criteria into future observational clinical studies and trials.
The experience of social (in)visibility in narratives about ostracism
Authors: Konieczna Agnieszka
Published: July 2024

This work involves a comprehensive review of qualitative research focused on analysing the experience of social ostracism. The voices of the ostracized are essential for uncovering that subtle, small, invisible, and silent practices of social exclusion, such as not paying attention, treating someone like air, lack of interest, or being left out, are sufficiently real and painful enough for those who have to deal with them. The term “social (in)visibility” allows us to openly name feelings that are an internal response to external ostracism, but which remain unexpressed in everyday interactions. The article focuses on understanding the role of social attention and social recognition in social encounters. As the social challenges described document a set of practices that prevent engagement in social interactions and reinforce cultural otherness, the construct of “social (in)visibility” may thus provide a framework for explaining how the lack of acknowledgment of someone’s presence in an appropriate manner in a given situation initiates the process of excluding those with so-called ‘spoiled identities’ and may help reveal mechanisms of escalating negativity. The work concludes with reflections on future research areas and the practical implications of social (in)visibility within the context of social relationships, co-presence, and social encounters.
Molecular pathogenesis of microsatellite instability-high early-stage colorectal adenocarcinoma in India
Authors: Ariyannur Prasanth , Menon Veena P. , Pavithran Keechilat , Paulose Roopa R. , Joy Reenu A. , Vasudevan Damodaran M.
Published: July 2024

Objectives

The prevalence of microsatellite instability (MSI) subtype among all colon cancers in India is about 30 %, approximately two times more than that of western population suggesting different molecular pathogeneses.

Methods

A NanoString analysis-based Pan cancer differential expression (DE) profile was determined in a primary cohort of early-stage CRC (tumor=10, normal=7), and correlated against MSI status. Using RT-PCR, tumor-specific DE genes were validated in another cohort of MSI-high CRC (n=15).

Results

Among the most differentially expressed genes, AXIN2, ETV4, and RNF43 were tumor cell-specific signals, while a set of genes including COL11A1, COMP, INHBA, SPP1, MMP3, TLR2, and others were immune cell-specific signals, that had a differential expression between MSI and MSS groups. When overlapped with The Cancer Genome Atlas (TCGA) studies using the Tumor immune estimation resource tool (TIMER), and protein-protein interaction analysis by STRING.db, these genes were segregated to representative tumor cells and immune cells. On validation, the tumor-specific gene signals were inversely associated with TLR4 expression.

Conclusions

The differential expression distribution of AXIN2, ETV4, and RNF43 among tumor and immune cells, suggests more than one pathological subset in the MSI-H subgroup of early-stage CRC in the Indian population.
“It Would be Helpful to Know Which Textbook Teaches the ‘Dialectic’ he Advocates.” Inserting Lukács into the Neurath–Horkheimer Debate
Authors: Tripodi Paolo
Published: July 2024

The present article aims at providing some clarification on the Horkheimer-Neurath 1937 debate, so as to make three main claims: (a) around 1937 (even though perhaps neither in the early 1930s, at the time of his review of Mannheim’s Ideology and Utopia, nor after the Second World War, at the time of Adorno’s disenchanted statement, “the whole is the false”), Horkheimer belonged to the Hegelian-Marxist tradition stemming from Lukács’s History and Class Conscioussness (1923); (b) notwithstanding Neurath’s semantic and epistemological holism, his fallibilism, his rejection of Wertfreiheit in the social sciences, his commitment to socialism, there is still a gulf between his position and Horkheimer’s, for Neurath did not accept the main methodological claim made by the latter, namely, the Lukács-inspired view that what “constitutes the decisive difference between Marxism and bourgeois thought” is the Hegelian “point of view of totality”; (c) highlighting the main differences between Neurath’s and Lukács’s versions of Marxism – one concerning the very idea of dialectic, and the other concerning the epistemic privilege of the proletariat – can throw some light on and help understand better the distinctive features of Lukács’s Hegelianization of Marxism.
Ahasvérus lakomája – Visky András: Kitelepítés
Authors: Borbély András
Published: July 2024

Borbély andrás kritikája Visky András Kitelepítés című regényéről.
TRANSFORMACIÓN GENÉRICA DE LA CRÓNICA PERIODÍSTICA EN SU PASO DE LAS PUBLICACIONES IMPRESAS A LOS MEDIOS DIGITALES EN AMÉRICA LATINA
Authors: Juárez Vázquez Gerardo
Published: July 2024

El artículo analiza el papel de la crónica dentro de la tradición periodística en América Latina desde su estabilización como género hasta su transformación provocada por las nuevas tecnologías de comunicación. El estudio se centra en indagar cómo las condiciones de producción han afectado la manera de escribir, producir y hacer circular crónicas en el contexto actual, así como las posibilidades que esta configuración mediática ha traído consigo.
ORSAI: UNA COMUNIDAD LITERARIA EN LA ERA DIGITAL
Authors: Sosa Cristina Patricia
Published: July 2024

Los lectores de Orsai constituyen una comunidad que se basa en una proximidad afectiva generada y promovida por su responsable principal, el escritor Hernán Casciari. Quienes realizan y quienes consumen la revista establecen un vínculo que trasciende la relación entre director y lector. Nos proponemos indagar tanto las particularidades de dicho vínculo como el modo en que las condiciones de un contexto digital dejan huellas en la publicación. Llevar adelante una revista en la era digital facilita algunos aspectos del proceso (como un circuito de circulación más fluido y económico), pero paradójicamente también trae aparejadas una serie de dificultades (el de la propiedad intelectual, por mencionar un ejemplo). Finalmente, nuestro objetivo es explorar los contenidos de la revista para acercarnos a la noción de literatura que presenta, una concepción que está en consonancia con la era de la posautonomía o de la inespecificidad.
OPINIÃO (1972-1977) E OS LIMITES DA FRENTE AMPLA
Authors: Candido Jeferson
Published: July 2024

O artigo busca resgatar a experiência do semanário Opinião como veículo de frente da oposição à ditadura civil-militar instalada no Brasil com o Golpe de 1964. Publicado no Rio de Janeiro, entre novembro de 1972 e abril de 1977, Opinião acabaria sendo atingido fatalmente, e paradoxalmente, pela abertura do regime iniciada em 1974 no Governo Geisel. As diferenças entre os diversos grupos de distintos matizes políticos – até então colocadas em segundo plano diante da luta comum – acabam por se mostrar incontornáveis em sua própria redação. A perspectiva da volta da disputa pelo poder acaba, por fim, esvaziando sua função antes mesmo de a redemocratização se consolidar.
MULHERES INTELECTUAIS EM REVISTAS CULTURAIS: A PROPÓSITO DE ALMANAQUE – CADERNOS DE LITERATURA E ENSAIO
Authors: Link Martins Mariana , Fonseca Claudia Lorena
Published: July 2024

Partindo do pressuposto de que as revistas culturais latino-americanas são objetos de investigação para compreender o contexto em que estão inseridas (CRESPO, 2011), este artigo tem como objetivo lançar um olhar sobre Almanaque – Cadernos de Literatura e Ensaio, com foco em seu décimo número, intitulado “Mulher Objeto… de Estudo”, publicado em 1979, identificando-a como um periódico que permitiu a atuação e colaboração feminina, e que abordou em suas páginas questões relacionadas às mulheres de forma coerente com as premissas feministas, contribuindo, assim, para a legitimação das mulheres brasileiras enquanto intelectuais, mesmo no contexto complexo do regime militar brasileiro e considerando a estigmatização dos estudos feministas à época. Para tanto, nos valemos das teorias de autoras feministas, como Silvia Federici e Marta Nunes da Costa, além de outros estudiosos, para refletir sobre a emergência das mulheres na cena intelectual.
RADICALISMO E INOVAÇÃO: AS CONTRIBUIÇÕES CRIATIVAS DE EMERSON ABREU NAS ESTRATÉGIAS NARRATIVAS DO UNIVERSO TURMA DA MÔNICA
Authors: Paiva Rodrigo Sérgio Ferreira de , Lins Aline Maria Grego , Ferreira Alexandre Figueirôa
Published: July 2024

O presente artigo busca verificar o impacto das contribuições criativas do roteirista Emerson Abreu na construção dos padrões estético-narrativos das Histórias em Quadrinhos da Mauricio de Sousa Produções (MSP). Identifica-se através de uma pesquisa exploratória e de caráter qualitativo que o desenvolvimento de personagens secundárias, o uso de temáticas e linguagens polêmicas e a construção de narrativas interligadas são exemplos de inovações estratégicas que moldam o atual contexto criativo e comercial do estúdio da MSP. A partir do referencial teórico de autores como Salles (2004), Maingueneau (2001), Ostrower (2001) e Shirky (2011), compreende-se como as peculiaridades do artista e suas marcas estilísticas resultam na construção de uma demanda específica advinda do público infanto-juvenil, que passa a reivindicar novos produtos editoriais de autoria exclusiva do quadrinista Emerson Abreu através do ciberativismo. Foi possível averiguar, ainda, os documentos de processo criativo que descrevem a evolução de valores estéticos e morais agregados pelo quadrinista nas distintas narrativas do universo Turma da Mônica, o que inclui dimensões de ordem linguística, cultural e sociológica.
Escrever, ler, ensinar: cruzamentos entre escrita criativa e formação de professores de literatura
Authors: Grando Diego
Published: July 2024

Se a área da Escrita Criativa, em seu atual estágio de desenvolvimento no Brasil, ainda está prioritariamente voltada para um público interessado em construir uma carreira de escritor – que procura formações desse tipo com o intuito de praticar, de forma mais sistemática e aprofundada, a escrita literária –, não significa que as experiências e reflexões produzidas em seu seio nada tenham a oferecer às licenciaturas em Letras, tanto aos estudantes – futuros professores de literatura – quanto aos docentes. Neste trabalho, busco justamente estabelecer relações entre a Escrita Criativa e a formação de professores de literatura, valendo-me da produção acadêmica de ambas as áreas. Parto da constatação do desinteresse pela prática da escrita no ensino universitário de literatura, associando tal desinteresse à concepção tradicional de ensino vigente nos cursos de Letras do país e refletindo sobre seus impactos no ensino escolar, com base em estudos de Bordini e Aguiar (1983), Castanho (2012), Cosson (2009), Dalla Bona e Martins (2016), Mazanatti (2007), Segabinazi (2011) e Segabinazi e Lucena (2016). Em seguida, discuto dois aspectos centrais para campo da Escrita Criativa: a metodologia da oficina, a partir de Ander-Egg (1991), e o caráter indissociável e solidário entre escrita e leitura que se estabelece em uma oficina de escrita, segundo Dawson (2005) e Houdart-Merot (2018b, 2019). Destaco, por fim, a relevância da prática da escrita literária durante o percurso formativo do futuro professor de literatura, conforme abordada por Sant’Anna (1977) e Antunes (2015), e assinalo a pertinência das contribuições da Escrita Criativa para se repensar o ensino de literatura na universidade.
POR UM QUADRO CONCEITUAL DOS PROCESSOS DE CONSTRUÇÃO DA IDENTIDADE RACIAL
Authors: Santos Camila Leopoldina Batista dos
Published: July 2024

Este artigo tem como objetivo apresentar e argumentar em favor de um quadro conceitual para a análise e interpretação dos processos de construção da identidade racial. Esse quadro se fundamenta na literatura sobre narrativas biográficas, refletindo sobre categorias teóricas como performatividade, iterabilidade e citacionalidade, contextualização e trajetórias textuais com forte potencial para compreensão das experiências pessoais com o racismo narradas que circulam pelo tempo e espaço. Esse quadro, além de permitir uma desnaturalização da identidade racial, possibilita uma compreensão dos processos de positivação da identidade negra que vem acontecendo ao longo dos anos e da responsabilidade dos falantes ao entextualizar determinados discursos e ao interpelar os sujeitos em suas subjetividades construídas por meio da linguagem.
Sintaxe e pandemia: uma experiência de afeto na linguagem
Authors: Diedrich Marlete Sandra , De Oliveira Marina
Published: July 2024

Aborda-se o tema do ato narrativo como ato enunciativo, na perspectiva benvenistiana, com enfoque na relação do falante com a língua-discurso em situação particular de ensino de língua no contexto de uma turma de licenciatura em Letras, durante o ano de 2020, em plena pandemia de Covid-19. A situação particular de ensino  desencadeou a produção da obra Sintaxe e Pandemia: uma experiência de afeto (2020). Pretende-se, com esse tema, refletir sobre a subjetividade no ato de narrar eventos particulares e os deslocamentos no universo da linguagem a partir desse modo de estar na língua. Estabelece-se, dessa forma, um diálogo entre os princípios enunciativos e a Linguística Aplicada, o qual permite afirmar que ato narrativo concebido como ato enunciativo revela dois deslocamentos importantes na linguagem: a relação entre o geral da língua e o particular do discurso; o poder significante da língua, capaz de fazer o mundo recomeçar ao representar o acontecimento através do ato narrativo.
LITERATURA, EDUCAÇÃO E RELAÇÕES ÉTNICO RACIAIS: UMA ANÁLISE DO CONTO O PECADO DE LIMA BARRETO
Authors: Campos Lillian Carlos , De Pinho Camila Maria Santos , Willms Elni Elisa
Published: July 2024

Literatura, questões raciais e educação são três potentes eixos de reflexão para uma equidade na educação brasileira. A lei 10.639/03 discute o ensino da cultura africana e afro-brasileira nas escolas. Para contribuir com esse processo o objetivo do texto é analisar o conto “O Pecado” de Lima Barreto, escrito em 1924, um texto literário que evidencia as violências raciais na construção do que é ser negro no Brasil e os enlaces que essas questões desencadeiam ainda hoje. Traça-se um paralelo entre a vida do autor do ponto de vista profissional e pessoal, com as discussões de sua narrativa vivida que foi transposta para a ficção. Empresta-se de Conceição Evaristo o conceito de “escrevivências” para debater a narrativa negra enquanto potência de discussão social e de mudança coletiva.  O conceito de epistemicídio para Sueli Carneiro, endossa a discussão do negro intelectual invalidado no ambiente intelectual e, Renato Noguera, auxilia na compreensão, por meio da epistemologia afroperspectivista, para pensar uma equidade na educação com potência para a libertação humana.  Enquanto resultado da análise observa-se que a obra de Lima Barreto apresenta-se ainda hoje como uma crítica social à condição do negro através de uma analogia religiosa presente no conto em análise. A literatura, por sua vez, é um importante instrumento que permite aferir os desafios da negritude em espaços de intelectualidade levando a discutir as disparidades destes. Por fim, considera-se que o negro-autor é também o objeto narrado e ficcionado na sua escrita em que escreve de um local em que a literatura rompe os limites da palavra texto, para pensar a palavra-viva: ainda ouvimos a sua voz e o seu clamor!
A FICÇÃO ESPECULATIVA COMO VISLUMBRE DO PÓS-HUMANISMO EM ORYX E CRAKE: PARALELOS QUE SE CRUZAM NAS OBRAS DE MARGARET ATWOOD E NIKOLAI LUTOHIN
Authors: Santos Luiza Prates dos
Published: July 2024

O intuito deste artigo é estabelecer as relações entre as narrativas de Margaret Atwood, na obra Oryx e Crake e as ilustrações do artista Nikolai Lutohin. A narrativa de ficção científica vem ganhando mais popularidade devido ao seu caráter especulativo, tendo subvertido suas noções de futurismo fantástico e aproximando-se da realidade cada vez mais. Pensaremos nas narrativas visual e textual como referências hodiernas, principalmente no âmbito da tecnologia, salientando o caráter de representação, tendo como eixo principal os elementos do pós-humanismo que conduzem e fundamentam a reflexão crítica de tais obras. Assim sendo, é através de passagens do livro que construiremos o olhar conjunto às imagens, realizando uma leitura atenta das obras e a relevância de pensarmos nas implicações do pós-humanismo.
LINGUAGEM, NARRATIVAS E SUBJETIVIDADES
Authors: Freitas Leticia Fonseca Richthofen de
Published: July 2024

Apresentação dossiê LInguagem, narrativas e subjetividades
CONSUMER ACCEPTANCE, ATTITUDE AND KNOWLEDGE STUDIES ON ALTERNATIVE PROTEIN SOURCES: INSIGHT REVIEW
Authors: Can Başak , Majoo Fuzail , Öztürkcan Arda
Published: July 2024

As the world's population grows and climatic conditions worsen, the world's current resources are rapidly depleting. Human behavior exacerbates this adverse situation. One of these behaviors is traditional eating habits. A traditional diet that consists of animal-based proteins consumes more resources and pollutes the environment to a greater extent. The traditional diet, which consists of mostly animal-based proteins, may turn towards plant-based proteins. In addition to plant-based proteins, in recent years scientists have focused on exploring alternative protein sources that do not pollute the environment and require fewer resources. Plant-based proteins, algae, insect-based proteins, and cultured meat have all been identified in the literature as alternative protein sources that may be consumed alone (in dry or concentrated form) or added to foods. While alternative protein sources are still being developed, the consumer's opinion on these sources is being assessed. So, in this review, consumers' knowledge, acceptance, and attitude to alternative protein sources are discussed. Data shows that plant-based protein sources, including algae, are now widely claimed to be more accepted than traditional protein sources. It has also been established that most individuals are prejudiced toward insect-based protein and cultured meat due to lack of sufficient information.
Mexican Catholic Women and Their Gendered Racial Politics
Authors: Álvarez-Pimentel Ricardo
Published: July 2024

This article examines pedagogical materials and Catholic youth magazines to uncover how, between 1926 and 1939, the Juventud Católica Femenina Mexicana (JCFM) pursued peasant moralization campaigns driven by young women’s shared distrust of Indigenous and mixed-race campesinas. It unearths the authoritarian dimensions of the group’s educational initiatives and exposes these efforts as fundamentally racial, gendered, and class-conscious political and religious projects. Moreover, this article traces how the JCFM, as an influential upper-class laywomen’s group, tried—and failed—to establish a nationwide educational curriculum grounded in Church doctrine to counter the influence of Protestant missions and Mexico’s nascent Secretariat of Public Education. It attributes these shortcomings to laywomen’s adherence to social hierarchy and their reluctance to offer meaningful solutions to peasant women’s economic hardships.
QUANTUM THEORY OF NONLINEAR PLASMONICS DEVELOPED BY S. G. RAUTIAN
Authors: ДРАЧЕВ В.П.
Published: July 2024

Рассмотрены резонансные свойства локального поля фрактальных кластеров металлов. Исследуются эффекты гигантского комбинационного рассеяния, усиления фотолюминесценции и нелинейных откликов. Демонстрируется, что модель Раутиана, основанная на квантовой теории нелинейности, предлагает более точное описание, чем предыдущие теории. Среди научных результатов теории Раутиана и его учеников можно выделить следующие: металлические наночастицы с диаметром <30 нм демонстрируют дискретные энергетические уровни в отличие от полупроводниковых квантовых точек; теория Раутиана предоставляет точное описание линейной части диэлектрической проницаемости, соответствующее классической модели Друде; кубическая нелинейная восприимчивость по модели Раутиана совпадает с экспериментом, указывая на вклад электронов проводимости.

Resonance properties of the local field of metal fractal clusters are considered. The effects of surface-enhanced Raman scattering, photoluminescence enhancement, and nonlinear responses are studied. It is demonstrated that the model developed by S. G. Rautian, based on the quantum theory of nonlinearity, offers a more accurate description than previous theories. Among the scientific results of the theory proposed by Rautian and his team, the following points can be highlighted: metal nanoparticles with a diameter < 30 nm exhibit discrete energy levels, in contrast to semiconductor quantum dots; Rautian’s theory provides an accurate description of the linear part of the dielectric function, corresponding to the classical Drude model; the cubic nonlinear susceptibility according to Rautian’s model is consistent with experiments, indicating the contribution of conduction electrons.
RESOLUTION ENHANCEMENT IN OPTICAL MICROSCOPY USING SUBPIXEL SHIFTS
Authors: ГУЖОВ В.И. , ИЛЬИНЫХ С.П. , АНДРЮЩЕНКО Е.В. , ХАЙДУКОВ Д.С.
Published: July 2024

В статье рассматривается новый метод повышения разрешения в оптической микроскопии методом пространственных субпиксельных сдвигов, т. е. сдвигов на некоторую величину, меньшую, чем разрешение, обеспечиваемое объективом. Разрешение оптических микроскопов определяется типом используемых объективов. Профессиональные микроскопы имеют набор микрообъективов с различным увеличением, которые монтируются на турели, содержащие несколько объективов. Иногда целесообразнее вместо набора микрообъективов использовать один объектив, если есть возможность обеспечить субпиксельные сдвиги. Повышение пространственного разрешения осуществляется с помощью аналитического выражения для спектра сгенерированных изображений. При этом спектр функции дополняется множителем, вид которого зависит от вида апертуры объектива. Для определения высокоразрешающих элементов необходимо разделить Фурье-спектр изображения, полученного из нескольких сдвинутых на субпиксельную величину изображений, на множитель, зависящий от выбранной апертуры. Этот множитель называется апертурной функцией. Апертурная функция определяется типом используемого объектива и может являться его паспортной величиной. В статье показан экспериментальный способ калибровки объектива (получение его апертурной функции) с низким разрешением (8×) на основе изображений, полученных с помощью объективов с большим разрешением (40×). Определив апертурную функцию, можно использовать один объектив с небольшим разрешением для получения изображений с любым разрешением менее разрешения выбранного объектива с большим разрешением (40×).

The paper deals with a new method of resolution enhancement in optical microscopy by the method of spatial subpixel shifts, i.e., shifts by some value smaller than the resolution provided by the objective lens. The resolution of optical microscopes is determined by the type of objective lens used. Professional microscopes have a set of microlenses with different magnifications, which are mounted on a turret containing several lenses. It is shown that a single objective lens can be used instead of a set of microlenses if subpixel shifts can be provided. An increase in spatial resolution is provided using the subpixel shift technique. In this case, the spectrum of the feature is augmented by a multiplier, whose type depends on the type of the lens aperture. To obtain high-resolution features, it is necessary to divide the Fourier spectrum of an image formed from several subpixel shifted images by a multiplier depending on the aperture type. This multiplier is called the aperture function. The aperture function is determined by the type of the lens used and can be its passport value. The paper illustrates an experimental method of obtaining the aperture function of a low-resolution (8×) lens calibration based on images obtained with high-resolution (40×) lenses. After determining the aperture function, one low-resolution lens can be used to acquire images with a resolution smaller than that of the selected high-resolution (40×) lens.
Demystifying the Stability and the Performance Aspects of CoCoSo Ranking Method under Uncertain Preferences
Authors: Dhruva Sundararajan , Krishankumar Raghunathan , Pamucar Dragan , Zavadskas Edmundas Kazimieras , Ravichandran Kattur Soundarapandian
Published: July 2024

This paper attempts to demystify the stability of CoCoSo ranking method via a comprehensive simulation experiment. In the experiment, matrices of different dimensions are generated via Python with fuzzy data. Stability is investigated via adequacy and partial adequacy tests. The test passes if the ranking order does not change even after changes are made to entities, and the partial pass signifies that the top ranked alternative remains intact. Results infer that CoCoSo method has better stability with respect to change of alternatives compared to criteria; and CoCoSo method shows better stability with respect to partial adequacy test for criteria.
Spatially structured beam formation for laser radiation control
Authors:   , Kontenis Gabrielius
Published: July 2024

Erdviškai struktūruotų pluoštų formavimas lazerio spinduliuotės valdymui
KELEA (Kinetic Energy Limiting Electrostatic Attraction) may explain electroculture and magnetoculture technologies in Horticulture
Authors: Martin W John
Published: July 2024

This article proposes that the mechanism of action of electroculture and magentoculture procedures is to increase the level of a specific form of energy in the groundwater termed KELEA, an abbreviation for Kinetic Energy Limiting Electrostatic Attraction. This energy is distinct from the energies obtained by plants from photosynthesis and food catabolism. Rather, KELEA supports what is referred to as the Alternative Cellular Energy (ACE) pathway in all forms of life. KELEA exists in conjunction with electrical charges with the probable fundamental purpose of preventing the fusion and annihilation of electrostatically attracted opposing electrical charges. It is presumed to be a radiating force that can lead to the quantitative loosening of the strength of hydrogen bonding of water molecules in its vicinity. This water is referred to be being KELEA activated. It can facilitate chemical reactions and engage in other cellular functions. Electroculture and magentoculture procedures can create oscillating electrical charges and, thereby, increase the local level of KELEA. These procedures can be compared with or used in conjunction with other means of increasing KELEA in horticultural and agricultural applications.
Significance of the Pledges of Tovste оf 1427 and 1444 in Politics of Gediminids and Jagiellonians
Authors: Ivashko Roman ,   Independent Researcher
Published: July 2024

The Tovste urban-type settlement is currently located in Chortkiv district of Ternopil region. This publication discusses the content of the relevant documents of 1427 and 1444 on donations of 100 marks in coins of that time each from Grand Duke of Lithuania Vytautas the Great and King of Poland Wladislaus III of Varna to members of the family of Hinkovyches. Both documents are stored in the Archive of the Radziwiłły family at the Main Archive of Ancient Acts in Warsaw. The grant of Duke Vytautas the Great was first published, obviously, by the medievalist, Prof Władysław Semkowicz. The latest generalizations about these donations belong to Dr. Janusz Kurtyka and Prof. Vitaliy Mykhaylovskiy. The document of 1427, given to Ivanko Hinkovych in Horodło, was apparently issued on October 2. The Grand Ducal seal is preserved. The provision was made in “grosses of Podolia”. But in fact, due to the fact that this is the common name of coins in circulation in Podolia at that time, it is difficult to determine the specific coin. The Lithuanian Duke did not directly indicate the merits for which the grant was awarded, so definition of the purpose of the donation is also based on assumptions. Apparently, in this way Duke Vytautas the Great sought to strengthen himself throughout Podolia, and perhaps this was part of his policy of establishing control even over all of Rus' and the Golden Horde. Simultaneously, the Lithuanian ruler had an obligation to establish the Church Union with Rome. The document of 1444, given to Bohdan Hinkovych in Orșova, was apparently issued on September 24. The royal seal is also preserved. The grant was probably made in the amount of 100 marks of Cracow, which was divided into 48 grosses. It was at that time that the anti-Ottoman Crusade was already underway under the general supervision of the Holy See in the person of the legate Julian Cesarini. Therefore, it makes sense to assume that the grant to Bohdan was made in the context of its organization. He could even be the direct participant of the campaign. The сrusaders felt an urgent need for recruits. In this case, the royal grants of this kind in Western Podolia and the royal domain of the Jagiellonians were important not only for Central and Eastern Europe, but for all Christians in general in the context of the rescue of Constantinople on the eve of 1453.
Arrhythmogenic Mitral Valve Prolapse: Can We Risk Stratify and Prevent Sudden Cardiac Death?
Authors: Cameron James N , Kadhim Kadhim I , Kamsani Suraya HB , Han Hui-Chen , Farouque Omar , Sanders Prashanthan , Lim Han S
Published: July 2024

Ventricular arrhythmias associated with mitral valve prolapse (MVP) and the capacity to cause sudden cardiac death (SCD), referred to as ‘malignant MVP’, are an increasingly recognised, albeit rare, phenomenon. SCD can occur without significant mitral regurgitation, implying an interaction between mechanical derangements affecting the mitral valve apparatus and left ventricle. Risk stratification of these arrhythmias is an important clinical and public health issue to provide precise and targeted management. Evaluation requires patient and family history, physical examination and electrophysiological and imaging-based modalities. We provide a review of arrhythmogenic MVP, exploring its epidemiology, demographics, clinical presentation, mechanisms linking MVP to SCD, markers of disease severity, testing modalities and management, and discuss the importance of risk stratification. Even with recently improved understanding, it remains challenging how best to weight the prognostic importance of clinical, imaging and electrophysiological data to determine a clear high-risk arrhythmogenic profile in which an ICD should be used for the primary prevention of SCD.
MI and Non-obstructive Coronary Arteries
Authors: Fatade Yetunde A , Newman Noah A , Patel Nidhi H , Mehta Puja K
Published: July 2024

MI and non-obstructive coronary arteries (MINOCA) is recognized as an important contributor to adverse cardiovascular outcomes in both men and women but is particularly prevalent in young women. Multiple coronary mechanisms such as coronary plaque disruption, coronary artery spasm, coronary microvascular dysfunction, spontaneous coronary artery dissection, and coronary thromboembolism can trigger MINOCA. Beyond routine left heart catheterization, invasive intracoronary imaging and cardiac MRI can help to clarify the cause of MINOCA. Conditions such as myocarditis, takotsubo syndrome, and cardiomyopathy are on the differential as alternate explanations in those suspected of MINOCA. Identification of the underlying cause in a case of MINOCA has therapeutic implications. While long-term management of MINOCA is not standardized, angiotensin converting enzyme inhibitors and statins appear to be of benefit. In this review, we discuss the prevalence and pathophysiology of MINOCA, diagnostic considerations, and current treatment approaches to manage this high-risk group of patients.
New Innovations to Address Sudden Cardiac Arrest
Authors: Shen Christine P , Bhavnani Sanjeev P , Rogers John D
Published: July 2024

Mortality from sudden cardiac arrest remains high despite increased awareness and advancements in emergency resuscitation efforts. Various gaps exist in bystander resuscitation, automated external defibrillators, and access. Significant racial, gender, and geographic disparities have also been found. A myriad of recent innovations in sudden cardiac arrest uses new machine learning algorithms with high levels of performance. These have been applied to a broad range of efforts to identify individuals at high risk, recognize emergencies, and diagnose high-risk cardiac arrhythmias. Such technological advancements must be coupled to novel public health approaches to best implement these innovations in an equitable way. The authors propose a data-driven, technology-enabled system of care within a public health system of care to ultimately improve sudden cardiac arrest outcomes.
Use of dynamic simulation and Forrester diagrams to describe the growth of lettuce (Lactuca sativa L.) under field conditions
Authors: Valery Alexis , Timaure Rossana , Darghan Contreras Aquiles Enrique , Gonzalez Sotomayor Nair Jose
Published: July 2024

The use of computational tools to describe some processes of crop growth has evolved in recent decades and remains an area of active research, where more and more applications are incorporated with the integration of a greater number of mathematical tools, statistics, and computational calculation efficiency, simplifying the tasks of modeling and visualizing the components of the system used. Current research proposes a dynamic growth model for lettuce cultivation using Forrester diagrams to evaluate different scenarios involving five growth functions and five lettuce cultivars in field conditions of the Bailadores region (Venezuelan Andes, 2550 m a.s.l.). The lettuce variety Coastal Star achieved the greatest accumulation of dry matter used as a response in each model. The logistics of growth function was properly adjusted to the experimental data compared to the other models. The proposed diagram model can be used as a basis for the construction of more complex models that incorporate other physiological variables of the crop and the growth environment.
French House, French Hype, French Touch
Authors: Vejmelka Marcel
Published: July 2024

Im Verlauf der 1990er Jahre findet in Frankreich im Bereich der elektronischen Musik eine Entwicklung statt, mit der das Land zu einem bedeutenden Standort auf der popmusikalischen Weltkarte wird. Das Etikett „French“ wird schnell zu einer Art Qualitätssiegel in der internationalen Wahrnehmung, die dazu geprägten Begriffe wie „French House“ werden fast umgehend auch im negativen Sinne eines „French Hype“ gedeutet und als Ausverkauf einer ursprünglich im „Underground“ angesie­delten Musik kritisiert. Zugleich aber wird dieser sehr heterogenen und vielseitigen Musik in ihrer Rezeption eine „französische Note“ zugeschrieben, die schwer greif­bar bleibt, aber kontinuierlich präsent ist. In diesem Sinne wirkt die Bezeichnung „French Touch“ im Rückblick sogar wie die Chiffre eines modernen Mythos im Sinne von Roland Barthes.
HIERGEIST, Teresa (ed.). 2024. „La crise est dans le pré. Négociations culturelles et esthétiques de l’agriculture dans le film français contemporain.“ Vistazo 4.
Authors: Lehnert Joris
Published: July 2024

Rezension
Die Vielfalt der „rumänischen Literaturen“ – entlassen aus der „Vormundschaft der Ideologie des Nationalstaates“
Authors: Baltag Ingrid
Published: July 2024

Rezension
Rectangular Stress Block and T-Section Behavior
Authors: Naaman Antoine
Published: July 2024

This is from the Open Forum - Problems and Solutions column.
Penggunaan Alat Peraga dalam Meningkatkan Minat Belajar Matematika Siswa
Authors: Sukandi Hasanuddin , Rahayu Yayu Nurhayati , Safitri Neng Risya , Zain Irfan Ahmad
Published: July 2024

Penelitian ini bertujuan untuk mengeksplorasi penggunaan alat peraga dalam meningkatkan minat belajar matematika siswa. Metode penelitian yang digunakan adalah penelitian kuantitatif dengan pengumpulan data melalui kuesioner. Penelitian ini dilakukan pada siswa-siswa sekolah menengah di SMPN 62 Bandung. Kuesioner digunakan sebagai instrumen pengumpulan data untuk mengukur minat belajar matematika siswa. Kuesioner terdiri dari pertanyaan yang dirancang untuk menggali minat belajar matematika siswa, termasuk aspek-aspek seperti ketertarikan terhadap materi matematika, kepercayaan diri dalam memecahkan masalah matematika, dan kepuasan terhadap pembelajaran matematika. Data yang dikumpulkan dari kuesioner kemudian dianalisis secara statistik. Hasil penelitian menunjukkan bahwa penggunaan alat peraga dalam pembelajaran matematika secara signifikan meningkatkan minat belajar siswa. Hal ini menunjukkan bahwa penggunaan alat peraga dalam pembelajaran matematika memiliki pengaruh yang positif terhadap minat belajar siswa. Oleh karena itu, disarankan agar sekolah dan guru-guru matematika mempertimbangkan penggunaan alat peraga sebagai strategi yang efektif dalam meningkatkan minat dan prestasi belajar matematika siswa.
Andrew Dalby and Maureen Dalby: The Shakespeare Cookbook
Authors: Thick Malcolm
Published: July 2024

Andrew Dalby and Maureen Dalby: The Shakespeare Cookbook: The British Museum Press, 2012: 144 pp., paperback, £10.99.
Reconsidering Late Medieval Architecture: Modernity, Reception and the Boundaries of the Gothic World
Authors: Foster Elisa
Published: July 2024

Review of Alice Isabella Sullivan and Kyle G. Sweeney, eds., Lateness and Modernity in Medieval Architecture, Leiden: Brill, 504 pages. ISBN 978-9004538436. This edited volume explores how medieval architecture from the thirteenth through seventeenth centuries has been described as both “late” in terms of the Gothic style and “modern” in its opposition to classical forms of the nascent Renaissance. Drawing from a wide array of architectural types as well as diverse examples from places ranging from Cyprus to the Dominican Republic, this volume provides a useful, insightful analysis of Gothic architecture that challenges traditional narratives and encourages a global perspective.
Análisis del conocimiento y uso de la resolución de problemas y la seguridad digital del profesorado extremeño
Authors: Cabanillas García José Luis
Published: July 2024

La presencia tecnológica está cada vez más presente en las instituciones educativas. Esto implica que el profesorado deba formarse y adquirir las competencias necesarias para un uso eficiente, destacando competencias que parecen no tener una clara importancia para el desempeño docente, tanto en la literatura científica, como para las administraciones públicas, como son la seguridad digital y la resolución de problemas. Este estudio plantea dar respuesta al objetivo general de investigación: Analizar el conocimiento y uso de la seguridad digital y la resolución de los problemas tecnológicos en los docentes de Extremadura. Para el desarrollo de la investigación, se ha utilizado una metodología cuantitativa, con un diseño de investigación no experimental transversal, donde se realizó un análisis de datos descriptivo e inferencial. A través de un muestreo aleatorio simple, se seleccionó una muestra representativa de 400 docentes que imparten docencia en Extremadura. Para la toma de datos, se ha utilizado un cuestionario ad-hoc para la evaluación diagnóstica de la competencia digital docente. Los resultados destacan la importancia actual de la seguridad digital debido a los avances tecnológicos y las amenazas cibernéticas, que pueden causar daños económicos, de privacidad y reputación. La resolución de problemas es esencial en la labor docente, permitiendo mejorar el desempeño y el aprendizaje de los estudiantes. Se observa que los docentes valoran el conocimiento y uso responsable de las tecnologías digitales, así como la gestión en la “nube” y el uso de herramientas digitales para la evaluación y seguimiento del alumnado. Se han encontrado diferencias en función del género, la titulación máxima y los habitantes del municipio en la seguridad digital y en función de la edad, experiencia docente y titulación máxima en la resolución de problemas.
Inteligencia artificial para potenciar la creatividad y la innovación educativa
Authors: Van Vaerenbergh Steven
Published: July 2024

La inteligencia artificial (IA) generativa ha emergido como una fuerza transformadora en la educación, ofreciendo nuevas posibilidades para la enseñanza y el aprendizaje. En este estudio, se exploran diversas aplicaciones de la IA generativa en el aula, destacando cómo estas tecnologías pueden mejorar la experiencia educativa y fomentar la creatividad y la innovación. Se examinan casos concretos de chatbots como ChatGPT y generadores de imágenes como DALL·E, evaluando tanto sus capacidades como sus limitaciones. A través de una revisión deexperiencias documentadas en la literatura académica, se analiza cómo la IA puede modificar y enriquecer las metodologías de enseñanza-aprendizaje, promoviendo un aprendizaje más dinámico y adaptado a las necesidades del siglo XXI. El objetivo es proporcionar una visión comprensiva de la IA generativa no solo como una herramienta de apoyo, sino como un elemento transformador en la educación contemporánea.
Género y estrés, ansiedad, depresión en estudiantes de psicología: un estudio postconfinamiento por covid-19
Authors: Campos Puente Alina de las Mercedes , Rico Chanamé Delia Gladys
Published: July 2024

Introducción: Una de las medidas más eficaces durante la pandemia de Covid-19 para disminuir los riesgos de contagio, fue el confinamiento en las casas, sin embargo, su repercusión ha sido negativa para la salud mental de la población; y los estudiantes universitarios no han quedado exentos de padecer estrés y sintomatologías ansiosas - depresivas. Objetivo: Conocer la relación existente entre género y estrés, ansiedad, depresión en estudiantes de Psicología. Todo ello con el fin de diseñar estrategias de intervención y tratamiento de la salud mental, en esta población. Método: Se realizó un estudio cuantitativo transversal, de corte inferencial correlacional, mediante muestreo intencional por conveniencia. Participaron 1069 estudiantes de Psicología, de la Universidad Privada San Juan Bautista, en Lima, el 77% (n=823) mujeres, 23% (n=246) hombres; edades entre 16 a 67 años (X=20.96, DS= 4,6). Utilizamos SPSSv26 para análisis de estadística descriptiva y comparaciones.Instrumentos utilizados: Cuestionario de datos sociodemográficos (ad hoc), Escalas de Depresión Ansiedad y Estrés (DASS-21) (Lovibond & Lovibond, 1995). Resultados: 1) En cuanto al estrés, no existen diferencias significativas entre hombres y mujeres. 2) Referente a la ansiedad, sí existen diferencias significativas, los hombres muestran mayor frecuencia de niveles normales de ansiedad, mientras que en las mujeres se evidencia mayor frecuencia de niveles moderados de ansiedad. 3) En lo concerniente a la depresión, la diferencia es ligeramente significativa entre hombres y mujeres,siendo mayor los niveles elevados, en ellas. Conclusiones: Durantelaetapa post-confinamiento por Covid-19, en los estudiantes de Psicología participantes, el género influye directamente en los niveles de ansiedad, siendo significativo que en las mujeres sea mayor la frecuencia de niveles moderados de ansiedad, que en los hombres.
Adolescentes interconectados. Evolución en los últimos años en alumnado de la ESO
Authors: Del Barrio Fernández Ángela , Portilla Ramos Carolina
Published: July 2024

Dado el entramado complejo de factores que influyen en la vida contemporánea de los jóvenes, consideramos esencial explorar el ámbito de las Tecnologías de la Información y la Comunicación (TIC) y su impacto en los estudiantes de la Educación Secundaria Obligatoria (ESO). La tecnología se ha integrado de manera contundente y significativa en el entretenimiento y el día a día de los adolescentes, destacando la necesidad de examinar y comprender cómo las TIC afectan sus vidas y cómo las manejan. Según Del Barrio (2017), los adolescentes ya no conciben sus vidas sociales o su tiempo de ocio sin una inmersión total en estas tecnologías. Sus modos de vida, predominantemente digitales, son extremadamente atractivos para ellos y a veces pueden resultar adictivos. Por lo tanto, nos propusimos como objetivos de este artículo identificar los patrones de uso de Internet y redes sociales por parte de los estudiantes de la ESO, evaluando cómo estos patrones han cambiado en un período de solo cuatro o cinco años y el efecto que estas tecnologías tienen en sus vidas. En cuanto a la metodología, hemos llevado a cabo una revisión bibliográfica centrada en los estudios de Andrade, B., Guadix, I., Rial, A., & Suárez, F. (2021) en su informe para UNICEF, y de Del Barrio (2017) en la Comunidad Autónoma de Cantabria. Además, hemos considerado ciertos indicadores del informe reciente de la OCDE (2024), titulado “Estudiantes, dispositivos digitales y éxito”, basado en los datos de PISA 2022. Este enfoque nos ha permitido generar una serie de reflexiones propias sobre los cambios observados en el intervalo entre estos estudios.