bluuebunny/crossref_metadata_2025 huggingface dataset:
Improvement and Recovery of Intestinal Flora Disorder Caused by Ciprofloxacin Using Lactic Acid Bacteria
Authors: Su Xiumin , Su Li , Cao Mengyuan , Sun Yulu , Dai Jinghan , He Yuanjie , Li Wei , Ge Wupeng , Lv Xin , Zhang Qiang , Cui Shenghui , Chen Jia , Yang Baowei
Published: September 2024

In this study, four lactic acid bacteria (LAB) strains demonstrating ciprofloxacin, bile salt, gastric fluid and intestinal fluid tolerance; as well as adhesion ability to Caco-2 and HT-29 cells were used to improve and recover the intestinal flora disorders caused by ciprofloxacin. Among which, Lactobacillus brevis 505 exhibited excellent adhesion ability to two kinds of cells and colonization ability to mouse intestinal. After ciprofloxacin treatment, certain recovery effect on cecum caused by ciprofloxacin in the mice was found during natural recovery (group 5C2), but it was challenging to fully restore the intestinal integrity to the initial level. After L. brevis 505 intervention (group 5C5), the intestinal damage to the colon and ileum caused by ciprofloxacin in mice was significantly alleviated, the recovery effect was better than that of natural recovery. Additionally, L. brevis 505 could effectively regulate INF-γ, sIgA and RegⅢγ increase induced by ciprofloxacin. Shannon and Simpson index of the intestinal flora of mice in 5C5 group were higher than those in other group, the relative abundance of Bifidobacterium and Lactobacillus in the mice in 5C5 group was increased, indicating that LAB can better restore the structure and abundance of intestinal microflora. Consequently, L. brevis 505 shows promise as a probiotic for gut microbiota restoration and rebuilding during antibiotic therapy.
Investigation of electrical properties at ambient and high temperature of Al 2 O 3 based Schottky barrier diodes structure using I-V, C-V and G/ω-V measurements
Authors: Hlali Slah , Bourguiba F. , Hizem Neila , Kalboussi Adel , Dhahri R. , Al-Syadi A. M. , Elkenany Elkenany Brens , Kossi S.
Published: September 2024

The study on the temperature effect on the electrical properties of aluminum in metal-insulator-semiconductor TiN/Al2O3/p-Si diodes found that temperature has a significant influence on its electrical properties. Temperature changes led to alterations in the interface states and series resistance, as well as affected the current-voltage (I-V), capacitance-voltage (C-V), and conductance-voltage (G/ω-V) characteristics of the diodes. Higher temperatures resulted in a decrease in interface states and a lower leakage current, indicating improved performance. These findings can contribute crucial information for optimizing the performance and reliability of semiconductor devices that utilize aluminum oxide as a gate dielectric in high-temperature applications.
Butyrate modulates the epigenetic landscape of human natural killer cells and affects their regulatory function
Authors: Laroni Alice , Carlini Federico , Squillario Margherita , Casella Valentina , Capaia Matteo , Lusi Valeria , Bagnara Davide , Colombo Monica , Palmeri Serena , Ivaldi Federico , Loiacono Fabrizio , Uccelli Antonio , Piana Michele , Laroni Alice
Published: September 2024

Gut bacteria-derived metabolites, such as butyrate (BUT), shape the function of T cells through inhibition of histone deacetylases (HDAC). Natural killer (NK) cells are innate lymphocytes with important effector and regulatory functions; little is known on the effect of BUT on NK cells. Here we aimed at evaluating whether BUT affects the epigenetic landscape of human NK cells. We found that BUT inhibits HDAC on human NK cells. Through ATAC sequencing, we demonstrated that BUT affects the chromatin accessibility of human NK cells, influencing, among others, genetic pathways related to immune regulation and response to viruses, and genes encoding for micro-RNAs. We identified, through analysis of published transcriptomic data, genes specific for NK-cell functional clusters, and we overlapped results of ATAC-sequencing, finding that BUT activates genes specific for CD56bright and CD56dim NK cells, and represses genes specific for non-classical NK cells. Through flow cytometry, we observed that BUT induces CD69 + NK cells and decreases CD56bright NK cells. Finally, we found that the suppressor function of CD56bright NK cells towards autologous CD4 + T cells was decreased by BUT. In conclusion, we show that BUT affects the epigenetic landscape of human NK cells, their phenotype and regulatory function.
Preparation of lead-coated sweet sorghum stalk-based carbon material and its electrochemical performance
Authors: Liang Qiuqun , Lan Xiaoqi , Liu Zheng , Ma Junjie , Han Guo-Cheng , Wang Hao
Published: September 2024

Sweet sorghum stalk can be used to prepare carbon materials and used in lead carbon battery negative materials. In this work, the sweet sorghum stalk was pretreated with 5 wt.% H3PO4, after heated at 550℃ for 105 min, lead-coated sweet sorghum stalk-based carbon materials were prepared by the solvent method, and their electrochemical performance were measured by cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS), as well as BET test, scanning electron microscope (SEM), energy dispersive spectroscopy (EDS) and X-ray powder diffraction spectrum (XRD) methods. The negative electrode materials contained lead-coated sweet sorghum stalk-based carbon material and physical grinding compared material were assembled into simulated lead-carbon batteries, the charge-discharge tester was used to test their first charge-discharge curves and cycle life curves, the first discharge specific capacity of two kinds materials were 73.0 mAh/g and 57.24 mAh/h, with 71.8% and 57.5% of capacity retention ratios after 150 cycles, respectively, shown that the simulated lead-carbon battery with new prepared carbon material exhibits better electrochemical performance.
Exploring the therapeutic potential of demethoxycurcumin in periodontitis
Authors: Reddy Saravanan Sampoornam Pape , Francis Delfin Lovelina , Thirumoorthi Harshini , Srivast Devendra , Katti Neelima , Chopra Sukhbir Singh
Published: September 2024

Objectives
This computational analysis investigated the potential benefits of Demethoxycurcumin (DMC) and studied the antimicrobial ligand binding sites of DMC specifically in the key endotoxin, Lipid A of P.gingivalis and host modulation with chemokine receptor of oral fibroblasts (CCR3/CCR4).
Materials and Methods
Protein structure preparation was performed using CHARMM force fields and protein-ligand docking was performed using Discovery Studio 2.0 software. DMC was docked with lipid A of P.gingivalis using the UCSF Chimaera program and the interactions in binding pockets of the resulting poses were analyzed using the VMD program.
Results
The results were promising, indicating a strong affinity between DMC and the active sites on the targeted proteins of P.gingivalis, suggesting a potential for DMC to interrupt the pathogenic mechanisms. The study identified several amino acid residues that are potentially capable of forming bonds with DMC, which may elucidate its mechanisms as an antimicrobial agent.
Conclusion
This study provides important data on the molecular efficacy of DMC, offering potential new approach for local drug delivery in combination with host modulation for management of periodontitis, which, if further developed and validated through clinical studies, could revolutionize periodontal therapy.
Clinical Relevance
Demethoxycurcumin is known for its anti-inflammatory and antimicrobial properties. Molecular docking showed that DMC can serve as a potential local drug delivery agent for periodontitis management. In addition to antimicrobial action against P.gingivalis, DMC also exhibits host modulating property on oral fibroblasts in molecular dynamic simulation.
Evaluation and modulation of bactericidal potential of different antibacterial agents against bacterial pathogens from conjunctivitis infections
Authors: arshad Saman , Ali Nazish Mazhar , Munir Sidra , Dar Mariam , Chaudhry Maham , Mazhar Bushra , Raza Muhammad Ahsan
Published: September 2024

Conjunctivitis is one of the most common disorders seen in hospitals. Youngsters under the age of seven are most likely to be diagnosed. The second highest point in the distribution is reached by women at age 22 and men at age 28. The goal of the current study was to identify and characterize the pathogens that cause conjunctivitis and determine their sensitivity against various antibiotics (such as metronidazole, ciprofloxacin, azithromycin, and levofloxacin), as well as aqueous plant extracts (Ficus religiosa, Syzygium cumini, Azadirachta indica, Allium cepa, Eucalyptus camaldulensis, Syzygium aromaticum, Aloe barbadensis, and Citrus limon) and their green synthetic silver nanoparticles. The samples were taken at Fatima Memorial Hospital, Lahore. The blood agar test was used for screening of pathogenic bacteria after samples were isolated. Types of hemolysis that the bacteria displayed were observed in order to assess the pathogenicity of the bacterial isolates. To monitor the antibacterial activity of particular pathogenic strains, the well diffusion method was employed. The outcomes demonstrated that every antibiotic was considerably more effective against isolated bacteria. Significant antibacterial activity against bacterial strains was demonstrated by E. camaldulensis, S. cumini, and C. limon (13.66±1.20 to 9±0.57, 15.5±0.76 to 10.33±1.45, and 21.33±0.88 to 12.66±0.33 respectively) out of all aqueous plant extracts. Green synthesized silver nanoparticles from A. barbadensis, S. aromaticum, C. limon, A. indica, F. religiosa and A. cepa displayed more noteworthy outcomes, with the zones of inhibition measuring 11.66±0.66 to 8.83±0.72; 12.5±0.62 to 9.83±0.72; 16.16±1.09 to 10.83±1.01; 13.33±1.20 to 8.83±0.72; 12.16±1.16 to 7.33±0.66, and 13.16±0.59 to 8.33±0.88 respectively. Bacterial strains were identified as Bacillus thuringiensis, Bacillus cereus, Bacillus paramycoides, Bacillus coahuilensis and Pseudomonas aeruginosa. This study showed that due to the rise in bacterial resistance to drugs, antibiotic medication may be replaced by biological antibacterial tools such as plant extracts and green synthesized silver nanoparticle formulations.
Efficient GNN-based Social Recommender Systems through Social Graph Refinement
Authors: Ga Sangmin , Cho Paul Hyunbin , Moon Gordon Euhyun , Jung Sungwon
Published: September 2024

Precisely recommending relevant items to users is a challenging task because the user’s rating can be influenced by various features. Therefore, social recommender systems have recently been introduced to leverage both the user-item interaction graph and the user-user social relation graph for more accurate rating predictions. Moreover, as Graph Neural Networks (GNN) have demonstrated superior performance in graph representation learning, several algorithms have been developed to incorporate GNN into social recommender systems. However, when the sizes of the social graph and user-item graph are very large, the computational complexity of existing GNN-based social recommender systems for aggregating user and item nodes becomes the primary bottleneck. In this paper, we develop a novel lightweight GNN-based social recommender systems (called LiteGSR) that mitigates the model complexity associated with aggregation operations while maintaining the quality of convergence. In order to efficiently reduce computational complexity, our proposed model refines the social graph by utilizing PageRank-based centrality scores of users and adapts representative virtual users on the user-item graph. Experimental results demonstrate that our new social recommender systems outperform existing state-of-the-art recommender systems in both convergence and training time.
Exploring Probiotic Potential: Lactic Acid Bacteria from traditional foods of Southern India
Authors: Madhankumar Mrithula Mahalakshmi , Xavier Janifer Raj , M Pal Murugan , Chauhan Om Prakash
Published: September 2024

Probiotics are highly essential for a healthy gut in order to maintain optimum microbial balance, fight pathogenic bacteria, improve digestion and maintain overall intestinal health. Southern India is characterized by an abundance of fermented traditional foods based on rice (Oryza sativa) with a diverse array of flavors and textures deeply rooted in its culinary practices. The present investigation was carried out to explore the probiotic potential in terms of acid tolerance, bile tolerance, tolerance to the gastrointestinal tract, antibacterial activity, and antibiotic susceptibility, of lactic acid bacteria (LAB) isolated from foods of Southern India. Analysis of variance (ANOVA) indicated that Limosilactobacillus fermentum DFRM9 had significantly (p<0.05) higher probiotic effects among the tested isolates and was used as a starting culture for sauerkraut preparation. The results obtained in the present investigation support the use of lacto-fermentation for the production of functional foods for improvement of human health and well being.
Impact of Grazing and Silvopastoral Systems on Carbon and Nitrogen in Sodic Soils of the Dry Chaco
Authors: Banegas Natalia , Santos Daniel Dos , Viruel Emilce , Gasparri Néstor Ignacio
Published: September 2024

Grazing and silvopastoral systems represent effective strategies for enhancing soil organic carbon (SOC) and total nitrogen (TN) availability in sodic soils. This study conducted a comprehensive assessment over a 6-year period to evaluate alternative cattle production methods aimed at increasing SOC and TN levels across various soil depths. Mineral-associated organic carbon (AOC) and particulate organic carbon (POC) fractions were analyzed to elucidate the dynamics of SOC. The experimental plots, totaling 9 hectares each, included pure pasture (PP), silvopastoral systems under tree canopy (SPS-UC), and silvopastoral systems between tree canopies (SPS-BC), all cultivated with Chloris gayana cv Epica INTA-Pemán. Trees of Neltuma alba (syn. Prosopis alba) were planted in the silvopastoral area in 1998. Statistical analyses focused on evaluating the impacts of these treatments, temporal effects, and their interactions on SOC, POC, AOC, and TN across four measurement points. Significant differences were observed in the distribution of SOC, POC, AOC, and TN between PP and SPS systems. Notably, SPS-BC exhibited the lowest SOC and TN values. Both PP and SPS-UC showed increases in SOC within the top 50 cm of soil depth, primarily attributed to elevated AOC levels. These findings underscore the potential of grazing and silvopastoral systems in increase soil fertility by increments in soil organic matter to mitigate sodic soil limitations. Moreover, the study highlights the necessity for further research in silvopastoral systems, with a high possibility in implementation for livestock production in Dry Chaco, to investigate how different tree configurations influence SOC and TN dynamics in these soils.
What Makes Them Well?: Examining First-Year College Students’ Quality of Life Using Latent Profile Analysis
Authors: Koo Katie , Kim Sohee
Published: September 2024

Analyzing data from 957 first-year college students, this study used latent profile analysis to distinguish subgroups of students based on their perceived quality of life and examined predictors of quality of life. We explored quality of life patterns and how demographic information, self-esteem, suicidal ideation, academic satisfaction, and social support impacted students classified by those patterns. We identified four patterns, focusing on dimensions of wellness based on the Holistic Wellness Model: psychological wellness, physical wellness, social wellness, and environmental wellness. We found that self-esteem, suicidal ideation, academic satisfaction, and social support significantly predicted first-year students’ quality of life. Implications for research and practice related to first year students’ quality of life are discussed.
Application of Taguchi Method to Determine Geomechanical Parameters of Jointed Rock Mass Based on Monitoring Results - Case Study: Siah bisheh Power Plant Cavern
Authors: Majnooni Alireza , Afrazi Mohammad , Yazdani Mahmoud
Published: September 2024

Evaluating rock mass parameters is a critical and complex aspect of rock mechanics. Although methods such as the Geological Strength Index (GSI) and conventional back analysis exist, their reliability can be compromised by potential errors. Integrating instrumentation results with back analysis for structures under construction, like caverns and tunnels, offers an efficient and accurate means of determining rock mass parameters. However, due to the numerous factors influencing rock mass behavior, conventional back analysis methods often fall short of delivering accurate results. In this research, we estimated the actual values of rock mass parameters using the Taguchi method, a systematic approach that minimizes the number of numerical analyses required. The Taguchi method was selected for its effectiveness in addressing the complex geometry, variable geological formations, and diverse geotechnical properties of the rocks at the Siah bisheh pumped storage project. Located on the Chalous River in northern Iran, the project comprises a dam and powerhouse, with the underground complex featuring three main caverns in close proximity. The powerhouse cavern measures 131.4 meters in length, 46 meters in height, and 24.5 meters in width. Various types of instrumentation, including extensometers, load cells, and convergence meters, are utilized in this project. Moreover, considering the favorable outcomes of the small strain model (HSS) in real-world projects where unloading plays a significant role, this study determines the parameters of this model and the stress ratio for the selected case using continuum numerical modeling with Plaxis 2D software. The displacements obtained from numerical modeling showed good agreement with the measured displacements, validating the accuracy of both the numerical modeling and the results obtained through the Taguchi method.
Food production diversity based on food groups is associated with minimum dietary diversity and dietary diversity among lactating mothers residing in subsistence farming households in rural Kyankwanzi district, Uganda
Authors: Buzigi Edward , Pillay Kirthee , Siwela Muthulisi , Mkhwanazi Blessing , Ngidi Mjabuliseni
Published: September 2024

Background
Consumsing a variety of food groups is a proxy indicator of micronutrient adequacy among women of reproductive age (WRA). This study examined the association between minimum food group production diversity (MFGPD) and minimum dietary diversity for women (MDD-W); and the correlation between food group production diversity (FGPD) and women's dietary diversity (WDD) among lactating mothers in rural Kyankwanzi district, central Uganda.
Method
Lactating mothers residing in subsistence farming households (HH) were recruited by systematic sampling. The outcome variables were WDD and MDD-W. A respondent scored either “1” or “0” if she consumed or did not consume the food group in the previous 24 hours, respectively. The WDD was calculated as the total of all food group scores. The respondent was considered to have achieved MDD-W if she consumed ≥ 5 out of the 10 food groups. The exposure variables were MFGPD and FGPD. The food groups used to classify foods on the farm were the same as the 10 food group classifications used in the MDD-W. The FGPD was calculated as the total of all food group scores. The MFGPD was achieved if the farm had ≥ 5 of the 10 food groups. The association between exposure and outcome variables was tested by logistic and linear regression models, where adjusted odds ratios (AORs) and adjusted correlation coefficient (β) were reported, respectively.
Results
Lactating mothers who achieved MFGPD were more likely to achieve MDD-W, AOR 8.6 (95% CI: 5.6–13.0, P < 0.0001); There was a positive correlation between WDD and FGPD, adjusted β:0.6 (95%CI 0.5–0.7, P < 0.0001).
Conclusion
The MFGPD is associated with MDD-W, while WDD increases as FGPD increases among lactating mothers in the study area. Promoting food production diversity based on food groups has the potential to improve WDD and achieve MDD-W among lactating mothers in the study area.
Robust Adaptive Generalized Correntropy-based Smoothed Graph Signal Recovery with a Kernel Width Learning
Authors: Torkamani Razieh , Zayyani Hadi , Korki Mehdi , Marvasti Farokh
Published: September 2024

This paper proposes a robust adaptive algorithm for smooth graph signal recovery which is based on generalized correntropy. A proper cost function is defined, which takes the smoothness and generalized correntropy into account. The generalized correntropy used in this paper employs the generalized Gaussian density (GGD) function as the kernel. The proposed adaptive algorithm is derived and a kernel width learning-based version of the algorithm is suggested. The simulation results confirm the performance of the proposed algorithm for learning the kernel-width to the fixed correntropy kernel version of the algorithm. Moreover, some theoretical analyses of the proposed algorithm are provided. In this regard, firstly, the convexity analysis of the cost function is discussed. Secondly, the uniform stability of the algorithm is investigated. Thirdly, the mean convergence analysis is also added. Finally, the computational complexity analysis of the algorithm is incorporated. In addition, some synthetic and real-world experiments show the efficiency of the proposed algorithm in comparison to some other adaptive algorithms in the literature of adaptive graph signal recovery.
Topological relations between crystal structures: a route to predicting inorganic materials
Authors: Kabanova Natalia A. , Grishina Ekaterina A. , Osipov Vladislav T. , Pavlova Valeria E. , Solodovnikova Maria A. , Kabanov Artem A. , Blatov Vladislav A.
Published: September 2024

We review topological approaches to the analysis of crystal structures of intermetallic compounds and to searching for structural relations between them as the relations between their underlying atomic nets. We introduce the concept of skeletal net to find the simplest system of interatomic contacts in intermetallic compounds, which supports the three-periodic crystal architecture. Using the observed approaches we have revealed topological relations between crystal structures of binary MeX compounds (Me = Re, Ti or Rh; X = B, C, N or Si) and found a key role of the body-centered cubic net in their topological hierarchy. We have explored the configuration space of the corresponding crystalline systems by generating all possible ‘subnet-supernet’ topological transformations, optimized the resulting topological motifs with DFT methods and found a new phase of RhB to be stable above 22 GPa. We discuss the role of topological representations in the prediction of new crystalline chemical substances.
Understanding the Morphogenesis of Hierarchically Porous Graphitic Aerogels Produced from Protein Precursors
Authors: Arnold Craig , Wani M. Shaharyar , Denzer Bridget , Caggiano Nick , Prudhomme Robert
Published: September 2024

Hierarchically porous graphitic sheet-based aerogels with high surface area and ultra-low density have drawn massive attention for applications in catalysis, energy storage/conversion, water purification, and beyond. Single-step pyrolysis of protein precursors for creating hierarchically porous monolithic graphitic aerogels with exceptional electrical, electrochemical, and mechanical properties has emerged as a sustainable and green approach. However, the formation mechanisms underlying the transformation of proteins into these aerogel structures remain to be understood. Herein, we demonstrate a self-foaming mechanism for the green and scalable synthesis of hierarchically porous monolithic sheet and fiber-structured graphitic aerogels using protein as a precursor. Rather than creating a solid phase and then exchanging the sacrificial component for a gas phase, we create a gas phase and then convert the liquid into a solid phase. The controlled heating of the protein precursors induces an intrinsic foaming action via initial softening followed by gas evolution and graphitization, resulting in a hierarchically porous graphitic aerogel composed of an integrated sheet and fiber framework. Our systematic exploration into the processing-structure-property relationships that govern aerogel optimization elucidates the interplay between tunable synthesis variables and resultant aerogel properties and structure, enabling deliberate control over microstructural features.
In situ spatial transcriptomic analysis of human skeletal muscle using the Xenium platform
Authors: Umek Nejc , Meznarič Marija , Šink Žiga , Cokan Kaja Blagotinšek , Zmrzljak Uršula Prosenc , Horvat Simon
Published: September 2024

Background: Traditional transcriptomic studies struggle to capture this heterogeneity of skeletal muscle, particularly at the fibre type-specific level. This study aimed to evaluate capability of the recently developed Xenium platform for conducting detailed spatial transcriptomic analysis of skeletal muscle histological sections.
Methods: Human vastus lateralis muscle samples from two individuals were analysed using the Xenium platform and Human Multi-Tissue and Cancer Panel which targets 377 genes. Successive tissue sections were additionally stained for specific Myosin Heavy Chain isoforms to differentiate between type-1 and type-2 muscle fibres. Muscle fibres were manually segmented which allowed for the comparison of transcript density between muscle fibre types and specific subcellular regions.
Results: Manual segmentation was crucial for accurate analysis as the automatic algorithms in the Xenium platform were inadequate for the precise segmentation of muscle fibres. The analysis revealed that transcript density was higher in type-1 compared to type-2 fibres, particularly in the nuclear and perinuclear regions where it was higher than in cytosolic region. Additionally, 191 out of 377 genes were differentially expressed between muscle fibres and the perimysium. Comparing the fibre types, specific genes such as PROX1, S100A1, LGR5, ACTA2 and LPL exhibited higher expression in type-1 fibres, while PEBP4, CAVIN1, GATM andPVALB showed higher expression in type-2 fibres.
Conclusions: We demonstrated that the Xenium platform is capable of high-resolution spatial in situ transcriptomic analysis of skeletal muscle histological sections. Manual segmentation of muscle fibres, although very labour-intensive, is currently required for successful differentiation of transcriptomic profiles between fibre types.
POLA PENDAMPINGAN DAN PEMBINAAN SISWA DALAM MENUMBUHKAN BUDAYA KEISLAMAN DI SMP AL IRSYAD SURAKARTA
Authors: Putri May Salma Magistra , Mustofa Triono Ali
Published: September 2024

Budaya keislaman ialah kultur, kebiasaan, atau aktivitas sehari-hari yang dilakukan oleh masyarakat dengan mengaitkan nilai-nilai Islam dalam kehidupan sehari-hari. Pendampingan dan pembinaan siswa menjadi salah satu solusi dalam melestarikan budaya keislaman terutama di lingkup sekolah. Pendampingan dan pembinaan siswa   berupaya untuk memberikan bimbingan, dukungan, maupun mempersiapkan peserta didik agar menjadi individu yang berkualitas dan terhindar dari dampak negatif.  Didasarkan dengan latar belakang tersebut, penelitian ini memiliki tujuan berikut, yaitu: (1) menggambarkan budaya keislaman dari aktivitas dan aturan yang berlaku di SMP Al Irsyad Surakarta sebagai tempat dimana peserta didik dapat melestarikan tradisi yang ada dalam agama Islam dan (2) mengulas peranan pendampingan dan pembinaan siswa melalui pola bina prestasi dalam bidang cerdas cermat Islami sejak program tersebut dicetuskan. Metode penelitian yang digunakan yaitu deskriptif kualitatif. Sumber data yang digunakan adalah kepala sekolah, guru pamong, guru dibidang kesiswaan, siswa kelas VII-XI, dan buku panduan dari SMP Al Irsyad Surakarta. Selanjutnya teknik pengumpulan data penelitian ini diperoleh dari observasi lapangan, pengumpulan informasi dengan narasumber yang terkait berupa hasil wawancara, serta dokumentasi rekaman dan gambar sebagai bahan pendukung penelitian. Kemudian data analisis dilakukan melalui tahapan yaitu pengumpulan data, reduksi data, penyajian data, dan penarikan kesimpulan. Sedangkan uji validitas bersifat triangulasi sumber guna mendapatkan keselarasan antara fenomena dengan beberapa narasumber. Hasil penelitian ini berupa bentuk budaya Islam dari upaya-upaya yang dilakukan SMP Al Irsyad Surakarta. Adapun wujud implementasi program bina prestasi secara umum dan spesifik di bidang cerdas cermat Islami. Program bina prestasi menjadi salah satu terobosan dua tahun terakhir sebagai sekolah Quran.
Pengaruh Model Project Based Learning (PjBL) dan Disiplin Belajar terhadap Hasil Belajar Qur’an Hadits melalui Penggunaan Unit Kegiatan Belajar Mandiri (UKBM) Siswa MAN 1 Medan
Authors: Sinaga Mahmud Qazzan Zaki , Daulay Afrahul Fadhila , Dahlan Zaini
Published: September 2024

Rendahnya hasil belajar mata pelajaran Pendidikan Agama Islam membutuhkan inovasi baru dalam pembelajaran di kelas. Hal ini menjadikan peneliti tertarik mengkaji rendahnya hasil belajar di MAN 1 Medan, dengan menggunakan inovasi baru dalam pembelajaran di kelas yaitu model pembelajaran Project Based Learning. Penelitian ini dilaksanakan di MAN 1 Medan.Populasi berjumlah 250 orang. Pengambilan sampel dilakukan dengan cluster random sampling berjumlah 70 siswa. Yaitu 35 siswa pada kelas XI IPA 7 yang akan di ajar dengan menggunakan model pembelajaran Project Based Learning (PjBL) dan 35 orang pada siswa kelas XI IPA 10 yang akan di ajar menggunakan Model pembelajaran Example non exampl. Tes konsep diri dilakukan untuk mengelompokkan siswa yang memiliki konsep diri tinggi dan siswa yang memiliki konsep diri rendah. Metode penelitian yang digunakan adalah kuasi eksperimen dengan desain faktorial 2 x 2. Uji statistik yang digunakan adalah statistik deskriptif untuk menyajikan data dan dilanjutkan dengan statistik inferensial dengan menggunakan ANAVA dua jalur dengan taraf signifikansi α = 0,05 yang dilanjutkan dengan uji Scheffe. Sebelumnya dilakukan uji analisis berupa uji normalitas dan uji homogenitas. Hasil Penelitian Menunjukkan: (1) Terdapat pengaruh pembelajaran Model Pembelajaran Project based learning (PjBL) terhadap hasil belajar Al-Qur’an Hadis siswa kelas XI IPA MAN Medan.  Dalam hal ini hasil belajar Al-Qur’an Hadis dengan pembelajaran Model Pembelajaran Project based learning (PjBL) lebih tinggi dari hasil Al-Qur’an Hadis siswa kelas XI IPA MAN 1 Medan yang di ajarakan dengan example non example. Hal ini juga terlihat dari rata-rata Disiplin Belajar pada kelas dengan perlakuan pembelajaran Model Pembelajaran Project based learning (PjBL) ( =86,7429) lebih tinggi dari rata-rata perlakuan pembelajaran siswa Kelas XI IPA MAN 1 Medan yang diajarkan dengan perlakuan Pembelajaran Example non example ( =81,2286). (2) Terdapat pengaruh Disiplin belajar Terhadap Hasil Belajar Qur’an Hadits Melalui Penggunaan Unit Kegiatan Belajar Mandiri (UKBM) Siswa MAN 1 Medan.  Dalam hal ini dapat dilihat dari rata-rata hasil belajar Al-Qur’an Hadis siswa kelas XI dengan motivasi belajar tinggi ( =87,60) lebih tinggi dari rata-rata hasil belajar Al-Qur’an Hadis siswa kelas XI IPA MAN 1 Medan dengan motivasi belajar rendah  ( = 85,60). (3) Terdapat interaksi antara  pembelajaran dan disiplin belajar Al-Qur’an Hadis siswa XI IPA MAN 1 Medan. Berdasarkan Interaksi nilai Berdasarkan Interaksi nilai F = 0, 376  di dapat nilai signifikan. (2-tailed) sebesar 0,002 berarti lebih kecil dari α 0,05, maka Ho di tolak. Berarti ada interaksi antara  penggunaan perlakuan pembelajaran dan Disiplin belajar.
Transformasi Kurikulum dan Sistem Pembelajaran di Pondok Pesantren Salaf pada Era Disrupsi
Authors: Marwiji Muh Hasan
Published: September 2024

Era disrupsi, yang ditandai dengan perubahan cepat dalam teknologi, budaya, dan sosial, juga memiliki dampak signifikan pada pondok pesantren. meskipun berbasis pada tradisi, pesantren memiliki potensi untuk bertahan dan bahkan berkembang pada era disrupsi salahsatunya adalah dengan melakukan transformasi kurikulum dan sistem pembelajaran. Penelitian ini bertujuan untuk menemukan pondok pesantren yang melakukan tranformasi kurikulum dan sistem pembelajaran di era disrupsi. Metode penelitian menggunakan deskriptif kualitatif untuk memahami dan menjelaskan fenomena sosial, budaya, atau perilaku dari perspektif yang mendalam dan komprehensif. Metode ini fokus pada menggambarkan dan memahami makna di balik data yang dikumpulkan, tanpa berusaha untuk mengukur atau menguji hipotesis secara statistik. Hasil penelitian menunjukan bahwa transformasi yang dilakukan pondok pesantren salaf dianaranya penyusunan visi dan misi serta standar lulusan, penyusunan program dan standar lulusan, menambah muatan materi pembelajaran yang disesuaikan dengan kebutuhan zaman, dan menyusun jadwal harian dan kegiatan secara rinci dan teratur.
Analisis Kecerdasan Emosional dan Intelektual terhadap Akhlak Remaja dengan Kegiatan Keagaman sebagai Variabel Intervening
Authors: Rosadi Adi
Published: September 2024

Masalah penelitian ini adalah rendahnya akhlak di kalangan siswa. Hal ini terlihat dari meningkatnya kasus tawuran, kekerasan, dan tindak kriminalitas di kalangan remaja. Metode yang digunakan yaitu deskritif dengan pendekatan kuantitatif. Sampel yang digunakan yaitu 100 siswa. Teknik pengumpulan data menggunakan angket. Analisis menggunakan Teknik SEM dengan SmartPLS versi 4 adalah metode untuk menguji hubungan antara variabel dalam model kompleks. SmartPLS versi 4 memfasilitasi analisis dengan fitur untuk model struktural, validitas, reliabilitas, dan pengujian hipotesis, terutama ketika data tidak normal atau sampel kecil. Berdasarkan hasil penelitian dapat disimpulkan bahwa Pertama, Kecerdasan Emosional berhubungan signifikan dengan Akhlak Remaja, dengan pengaruh sebesar 17,9%. Kedua, Kecerdasan Emosional memiliki hubungan yang signifikan dengan Kegiatan Keagamaan, dengan pengaruh sebesar 37,1%. Ketiga, Kecerdasan Intelektual memengaruhi Akhlak Remaja, dengan pengaruh sebesar 21,1%. Keempat, Kecerdasan Intelektual berhubungan signifikan dengan Kecerdasan Emosional, dengan pengaruh sebesar 50,2%. Kelima, Kecerdasan Intelektual memengaruhi Kegiatan Keagamaan, dengan pengaruh sebesar 47,5%. Keenam, Kegiatan Keagamaan berhubungan signifikan dengan Akhlak Remaja, dengan pengaruh sebesar 50,7%. Hasil uji ini menggambarkan kompleksitas hubungan antara variabel dalam penelitian, yang melibatkan faktor-faktor yang beragam.
Flux-tunable hybridization in a double quantum dot interferometer
Authors: Prosko Christian , Kulesh Ivan , Chan Michael , Han Lin , Xiao Di , Thomas Candice , Manfra Michael , Goswami Srijit , Malinowski Filip K.
Published: September 2024

Quantum interference of electron tunneling occurs in any system where multiple tunneling paths connect states. This unavoidably arises in two-dimensional semiconducting qubit arrays, and must be controlled as a prerequisite for the manipulation and readout of hybrid topological and parity qubits. Studying a loop formed by two quantum dots, we demonstrate a magnetic-flux-tunable hybridization between two electronic levels, an irreducibly simple system where quantum interference is expected to occur. Using radio-frequency reflectometry of the dots’ gate electrodes we extract an interdot coupling exhibiting oscillations with a periodicity of one flux quantum. In different tunneling regimes we benchmark the oscillations’ contrast, and find their amplitude varies with the charge state of the quantum dots. These results establish the feasibility and limitations of parity readout of qubits with tunnel couplings tuned by flux.
Higher Education – Digital Transformation: Strategies and Solutions to Developing Human Resources With Skills and Talents in 4.0 Industrial Revolution – Theory and Orientation
Authors: Xuan Dung Nghiem
Published: September 2024

The tendency of digital transformation has been apparent in almost all aspects of socio-economic life, of which tertiary education never stands an exception. Tertiary education holds the proper transformation strategies and orientations and catches up with the general trend, contributing to the development of the digital society and forming a digital nation in the future, which all require strategic and flexible solutions from the present time. The article analyzes some basic contents of digital transformation in higher education, factors guaranteeing successful digital transformation, assesses the current situation, and surveys regional, international, and domestic universities as well as the results and remainings, thereby proposing several strategies and theoretically oriented solutions to meet the requirements of developing skilled and talented human resources in the context of the Industrial Revolution 4.0 of Vietnam in the coming period.
El derecho de defensa y el principio de no autoincriminación de la persona jurídica: un análisis de derecho comparado
Authors: Cardenas Gonzales José Rolando , Yupton Vásquez Jhonatan Milton , Castañeda Méndez Juan Alberto
Published: September 2024

El derecho de no autoinculparse, parte del derecho de defensa, está reconocido en los tratados jurídicos internacionales. Su aplicación en el proceso penal y en las sanciones administrativas es indiscutible. Sin embargo, existe una tensión entre este principio y el procedimiento abreviado que lo exige. En este sentido, el objetivo del estudio fue realizar un análisis sobre el derecho de defensa y el principio de no autoincriminación de la persona jurídica en la legislación latinoamericana, a la luz de la jurisprudencia del Tribunal de Justicia de la Unión Europea (TJUE). Investigación cuantitativa, descriptiva, basada en la revisión de la literatura y el metaanálisis, que consintió el acopio de 10 artículos científicos entre los años 2019 y 2023, teniendo como tema central el derecho a la defensa y el principio de no autoincriminación de la persona jurídica como garantías fundamentales que impiden que se les obligue a declarar contra sí mismas o a confesarse culpables. En conclusión, la dignidad, la presunción de inocencia y el debido proceso de las personas que se enfrentan a una investigación o a una acusación penal se encuentran salvaguardadas por el derecho de defensa y el principio de no autoincriminación.
La regulación de la partería tradicional afrocolombiana del Pacífico: entre la exclusión y la inclusión
Authors: Moreno Potes Jhon Fredy , Hurtado Martínez José Estanislado , Hinestroza Cuesta Lisneider
Published: September 2024

A través del Ministerio de Cultura Colombia expidió la Resolución 1077 de 2017 declarando patrimonio cultural inmaterial de la nación la partería afro del Pacífico; sin embargo, aún la desconoce como práctica médica de un sistema de salud propio. Así las cosas, este artículo presenta una revisión de la normatividad expedida a partir de las Constituciones de 1886 y de 1991 con incidencia en este saber para determinar si el tratamiento jurídico otorgado, no solo como expresión cultural, sino también como práctica médica, se ajusta a los postulados de diversidad étnica, pluralismo y multiculturalidad. Para ello se empleó un diseño metodológico de corte cualitativo-descriptivo en aplicación del método deductivo a partir de un análisis de información legal y otros documentos, y se encontró que, a pesar de la apertura e inclusión constitucional vigente, persiste la exclusión legal de la partería afrocolombiana y la desprotección de las parteras afrodescendientes en el sistema de salud oficial
Instrumentos para la evaluación del apego adulto en población española: revisión sistemática
Authors: Bárez Palomo Nerea Betisa , Saúl Gutiérrez Luis Angel , Corbella Santoma Sergi
Published: September 2024

Este estudio tiene como objetivo identificar los instrumentos para la evaluación del apego adulto diseñados o adaptados para población española, describir sus propiedades psicométricas y determinar cuáles de ellos presentan mejores indicadores de validez, así como extraer otros criterios de utilidad para su utilización como medida del apego adulto en dicha población. Para tal efecto, se llevó a cabo una revisión sistemática de publicaciones que recogieran estudios de diseño, validación, adaptación o análisis psicométricos de instrumentos de medida del apego adulto en muestras españolas. Se realizó una búsqueda en diferentes bases de datos (PSICODOC, APA PsycArticles, APA PsycInfo, Psychology and Behavioral Sciences Collection, MEDLINE, Scielo Direct, SCOPUS y Dialnet), y se identificaron 12 investigaciones que cumplieron con los criterios de selección, las cuales presentan ocho instrumentos para la evaluación del apego adulto en población española. Se analizaron las propiedades de cada uno de los instrumentos atendiendo a la calidad metodológica y aspectos concretos sobre el apego evaluados. Se concluye que existen pocos instrumentos traducidos o validados con muestra española, y la mayoría de los existentes presentan buenas propiedades psicométricas para la evaluación del apego adulto. Con esta revisión se proporcionan claves para la selección de la herramienta más oportuna tanto en el contexto clínico como investigativo.
Factores protectores y de riesgo asociados a síntomas de ansiedad y de depresión: análisis de perfiles latentes y de predictores
Authors: Vizioli Nicolás Alejandro , Grasso Jimena Eliana
Published: September 2024

En la actualidad, la prevalencia de síntomas de ansiedad y depresión en la población general representa un problema para los sistemas de salud. Estos cuadros comparten síntomas, factores etiológicos y de mantenimiento. La presente investigación buscó identificar perfiles latentes de sintomatología ansiosa y depresiva, y posibles factores de riesgo y protección (variables sociodemográficas y estrategias de regulación emocional (RE)) en una muestra de 632 participantes con edades entre los 18 y los 65 años (M= 31,04; DE= 10,14), residentes en la Ciudad de Buenos Aires y el conurbano bonaerense (Argentina), a quienes se administró un cuestionario sociodemográfico, el Inventario de Ansiedad de Beck, el Inventario de Depresión de Beck y el Cuestionario de Regulación Emocional. Se identificaron tres perfiles caracterizados por su severidad sintomática. Mediante una regresión logística multinomial se halló que recurrir en mayor medida a la estrategia de RE reevaluación cognitiva, tener entre 40 y 49 años y niveles de ingresos medio-bajos, medios o medio-altos se constituyen como factores protectores; mientras que pertenecer al género femenino y la mayor utilización de la estrategia de RE supresión expresiva se presentan como factores de riesgo de sintomatología ansiosa y depresiva. Estos resultados ponen de manifiesto la importancia de considerar los factores protectores y de riesgo en el diseño de intervenciones con miras a reducir la severidad de los síntomas de ansiedad y de depresión, y mejorar la salud mental de las personas.
„Powiadam ci: «Dziś będziesz ze mną w raju»” (Łk 23,43)
Authors: Piwowar Andrzej
Published: September 2024

Słowa Jezusa skierowane do dobrego złoczyńcy z krzyża, przekazane w Łk 23,43, można przetłumaczyć z języka greckiego na dwa różne sposoby w zależności od tego, do której formy czasownikowej zostanie odniesiony przysłówek czasu σήμερον („dziś”). W zdecydowanej większości tłumaczeń na języki nowożytne zostały one oddane w sposób, który można określić jako tradycyjny: „Powiadam ci: «Zaprawdę dziś będziesz ze mną w raju»”. Można je przetłumaczyć także w inny sposób, który istotnie wpływa na teologiczny wydźwięk słów Jezusa: „Powiadam ci dziś: «Zaprawdę będziesz ze mną w raju»” (tłumaczenie alternatywne). Pierwsza część artykułu zawiera analizę użycia przysłówka σήμερον w Septuagincie, Nowym Testamencie oraz dziele Łukaszowym. W drugiej części artykułu próba rozstrzygnięcia badanego problemu została oparta na przesłankach teologicznych. Choć obie drogi analizy nie dają ostatecznego rozstrzygnięcia problemu, to interpretacja alternatywna lepiej wpisuje się w nauczanie Kościoła dotyczące zbawienia, które ostatecznie dokona się na końcu czasów.
Safer Senior Citizens Online
Authors: Racka Katarzyna
Published: September 2024

The dynamic development of digital technologies has significantly changed the way people communicate and work. Rapid technological expansion and a more widespread access to the Internet mean that traditional services are increasingly being abandoned in favour of online services. However, as technology advances, so do the risks associated with cyber threats. Hacking attacks, phishing or identity theft threaten the privacy and security of online users.This paper focuses on the situation of senior citizens in Poland in the context of the development of new technologies and cybersecurity. In the first part, the author analyses the latest reports on cybersecurity and cyber threats to seniors. In the second part, the author presents the results of her own research obtained from surveys conducted among people aged 60 and older.
Intercultural Competences and the Challenges of Teachers in Education for Peace
Authors: Mróz Anna , Kawula Anna
Published: September 2024

The article addresses the issues of the acquisition of intercultural competence by teachers in a dynamically changing multicultural context. The acquisition of multicultural competence is understood as a creative effort of each teacher in the process of self-development and, consequently, in the process of shaping a culture of peace, which is directly related to the quality of intercultural education, education for peace. The authors present the competences and challenges governing intercultural education in a multicultural context, analysing the ideas and attitudes stemming from the spirit of tolerance and the values attributed to the dialogue conducted both in the domestic and foreign spheres. Such an attitude allows for the acquisition of so-called multicultural competence and the rejection of stigmatisation, xenophobia or extremist attitudes.