bluuebunny/crossref_metadata_2025 huggingface dataset:
Kewarganegaraan dan Kesehatan: Partisipasi Warga dalam Penanganan Pandemi COVID-19 di Indonesia
Authors: Rachman Fazli , Fitra Ilham
Published: October 2021

This article aims to parse and identify the participation of citizens in handling the coronavirus pandemic in Indonesia. This article tries to “unfold” an overview of the relationship between citizenship studies and health. This research was conducted by a qualitative approach and descriptive design. Collecting data were obtained by using observation, documents study, interview, and literature study technique that was held on during January until Mei 2020. The data obtained were then analyzed by an interactive model. The research result shows that citizen has a central rule for handling the spread of corona virus. Citizen participation for handling COVID-19 conducted by educating people about coronavirus and COVID-19, and preventive measures. Another participation form is direct philanthropy action. Citizen participation for handling COVID-19 in Indonesia. Categories Level of citizen participation in Indonesia is the degree of citizen power. Urgent to develop synergy between state and citizen to improve the highest standard, comprehensive, and sustainable health.
Perlindungan Hukum Terhadap Bank Pembayar Talangan Haji
Authors: Muhammad Ilyas , Winarno Bambang , Safaat Rachmad
Published: October 2021

This study discusses legal protection for banks with the status of BPS BPIH in curbing haj bailout financing that has passed the provisions of the Indonesian Ministry of Religion, in Article 12A paragraph (3) of the Regulation of the Minister of Religion Number 24 of 2016 which formulates “In the event that there are still haj bailout funds has not been resolved after the deadline as referred to in paragraph (2) the portion number for Pilgrims is still active ”. This study uses a normative juridical method with a statutory approach and a conceptual approach. The result is legal protection for BPS BPIH in obtaining its right to obtain certainty of repayment of funds for financing the status of the portion of the hajj is still active as regulated in Article 12A paragraph (3) of the Regulation of the Minister of Religion Number 24 of 2016. The formulation of the settlement of haj bailout financing through the fulfillment of formal requirements the formation of legislation by involving the financial services authority in the company, and the material requirements, namely by accommodating the rights of all stakeholders of haj bailout financing.
Beyond Civilizational Dilague, Nipponshi: Ruang Lingkup Identitas Nasional Bangsa Indonesia
Authors: Adha Muhammad Mona , Susanto Erwin
Published: October 2021

Japanese culture is highly respected and maintained by its citizens. This study aimed to discuss the existence of Japan between 1944 and 1985 and the national identity of the Japanese people. The study used a non-interactive qualitative approach. This study used a non-interactive qualitative research approach, identified and researched concepts, then analyzed data and information about the history and existence of the Japanese nation including its development globally in the midst of international life. Japan, between 1944 and 1985, had entered a new era after the human tragedy, namely the bombing of Hiroshima and Nagasaki. Since the tragedy, Japan had undergone significant changes, namely better infrastructure. Besides, the Japanese were increasingly realizing that they were actually part of Asia. On this basis, the Japanese were called the Neoppons or the New Japanese. Japan’s unique national identity was reflected in the wa-ism philosophy, which was a concept of harmony between individuals and members of society.
Pendekatan Kontekstual dalam Meningkatkan Pembelajaran Pendidikan Pancasila dan Kewarganegaraan di Sekolah Dasar
Authors: Parhan Muhamad , Sukaenah Sukaenah
Published: October 2021

This study aimed to offer an alternative reconstruction of the fifth-grade Pancasila and Civic Education learning process at SDN Cugenang. This was done on the basis of thefinding that the learning that has been held so far tends to be theoretical-abstract and difficult for students to understand. The method used was a classroom action research method with four stages of activity, namely: planning, action, observation, and reflection, which are carried out in three cycles. In general, it could be concluded that Pancasila and Civic Education learning held in elementary schools with a contextual approach could make the learning process and outcomes better and more improved.
Analisis Tanggung Jawab Syahbandar dalam Pelayaran pada Kantor Kesyahbandaran dan Otoritas Pelabuhan
Authors: Jasruddin Jasruddin , Putra Zulfikar , Butuni Syarif
Published: October 2021

The purpose of this study was to determine the responsibility of the harbormaster in shipping. This study used an empirical juridical approach. The responsibility of the class II Kendari Harbormaster was very important because of security and safety for matters related to shipping. The harbormaster in his duties had to ensure the awareness of sea transportation service users and had the authority to impose sanctions.
Kerjasama Pusat Kegiatan Belajar Masyarakat dengan Pemerintah Desa sebagai Upaya Meningkatkan Partisipasi Pendidikan Masyarakat
Authors: Widiyantoro Webri
Published: October 2021

This study aimed to analyze educational strategies and patterns of cooperation between community learning activity centers and village governments, and analyze the constraints and efforts made in the process of increasing community education participation. The study used a qualitative approach with a case study method. The cases were chosen were typical cases that be able to represent similar cases, namely a form of collaboration between the community learning activity center and the village government. The qualitative data analysis used was pattern matchmaking analysis, to answer big questions related to strategies, forms, constraints, and solutions in building cooperation between community learning activity centers and village governments. The obtained results indicated that the strategies used by the community learning activity center in the process of increasing community education participation were in the form of community identification strategies, programs, and partnerships. The pattern of cooperation between the community learning center and the village government was in the form of coaching and mentoring, with the form of cooperation in the form of support for policy regulations, legal protection, budget assistance, mentoring, coaching, and motivation. The obstacles faced by the community learning activity center were weak community commitment and less than optimal program socialization. Efforts to overcome these obstacles were carried out by implementing performance and performance strategies and increasing innovation in disseminating educational programs.
Wujud Perlindungan Hukum Bagi Wanita Akibat Pembatalan Perkawinan Klandestin
Authors: Fi'li Dimas Auliya Fikri Bil , Soekesi Titik Soeryati
Published: October 2021

This study analyzed the form of legal protection for women who experienced the annulment of clandestine marriages. This study used an approach in analyzing problems with the approach of legislation and case approach, namely by looking at cases stemming from court rulings and statutory provisions. The results showed that the form of legal protection for women who experienced the annulment of clandestine marriage could be obtained based on Article 136 of the Civil Code, Article 279 paragraph (1), and 263 paragraphs (1) of the article on the Criminal Code. The responsibility of the man who performed clandestine marriage could be in the form of compensation and refund of the circumstances as before by making a statement containing a prohibition to perform the clandestine marriage act in the future.
SPREADING NATIONALISM IN THE EARLY 1900S: MARCO KARTODIKROMO'S TYPICAL APPROACHES IN INDONESIA
Authors: Ratri Annisa Meutia
Published: October 2021

This writing aims to describe Marco Kartodikromo and his unique approach to spread an idea about nationalism in the early 1900s. By using historical research as a methodology, this paper consisted discussion about basic idea that led Marco to birth the writing, which is as strategy to influence the society. This writing also provided Marco’s expounded on nationalism and his several typical approaches to spread of nationalism such as bringing historical consciousness and using low Malay language.  Marco was successfully creating threaten to colonizer an expressing the pain and suffering of the colonized people within nationalist discourses by the literature work such as Student Hidjo, Azia boeat Orang Azia and others. Penelitian ini adalah tentang Marco Kartodikromo dan pendekatan khasnya dalam menyebarkan ide tentang nasionalisme pada awal tahun 1900 di Indonesia. Dengan menggunakan penelitian sejarah sebagai metodologi, penelitian ini mencakup diskusi tentang ide dasar Marco dalam menulis dan strategi untuk mempengaruhi masyarakat.  Pada penelitian ini juga memberikan penjelasan  tentang nasionalisme dan beberapa pendekatan Marco untuk penyebaran nasionalisme seperti membawa kesadaran sejarah dan menggunakan bahasa Melayu yang rendah. Marco tidak hanya berhasil menciptakan ancaman bagi colonial tetapi juga dapat mengekspresikan rasa sakit dan penderitaan orang-orang yang dijajah dalam wacana nasionalis melalui karya sastranya seperti Student Hidjo, Azia boeat Orang Azia, dan karya lainnya.
The Management of Natural Resources in 10 – 14 AD, The Hindu-Buddhist Era, based on Old Javanese Inscription in the Malang Highlands, East Java: Environmental Archeology Study
Authors: Suprapta Blasius
Published: October 2021

Abstract: Based on geological studies, the Malang Highlands, East Java, Indonesia is a former ancient lake that dried up and turned into a wide and fertile plateau. Such natural conditions allow the growth and development of Hindhu-Buddhist civilization in 10 - 14  AD, namely the socio-cultural life of a well-ordered community. This includes the structure of natural resource management by the state and society. Around 19 old Javanese Inscription certificates were issued by the king at that time. Some of these inscriptions contain the standard rules of the kingdom in relation to the management of natural resources, but so far there has not been an in-depth study of the rules of natural resource management in this region. In connection with this problem, the need to conduct a study of natural resource management based on Old Javanese Inscription through an environmental approach: Environmental Archeology. The study was conducted by literature study, toponymy analysis, geographical spatial analysis on topographical maps, and interpretation of natural resource management, through an environmental management approach. The results showed that there were rules for felling trees in primary forest areas, state forest management for the benefit of maintaining sacred buildings and there were rules for the sale and purchase of endemic plants, namely spices. Abstrak: Berdasarkan studi geologi, Dataran Tinggi Malang, Jawa Timur, Indonesia merupakan bekas danau purba yang mengering dan berubah menjadi dataran tinggi yang luas dan subur. Kondisi alam yang demikian memungkinkan tumbuh dan berkembangnya peradaban Hindhu-Budha pada 10 - 14 Masehi, yaitu kehidupan sosial budaya masyarakat yang tertata rapi. Ini termasuk struktur pengelolaan sumber daya alam oleh negara dan masyarakat. Sekitar 19 akte Prasasti Jawa kuno dikeluarkan oleh raja saat itu. Beberapa prasasti tersebut memuat aturan baku kerajaan dalam kaitannya dengan pengelolaan sumber daya alam, namun sejauh ini belum ada kajian yang mendalam tentang aturan pengelolaan sumber daya alam di wilayah ini. Sehubungan dengan masalah tersebut, perlu dilakukan kajian pengelolaan sumber daya alam berbasis Prasasti Jawa Kuno melalui pendekatan lingkungan: Arkeologi Lingkungan. Penelitian dilakukan dengan studi literatur, analisis toponimi, analisis spasial geografis pada peta topografi, dan interpretasi pengelolaan sumber daya alam, melalui pendekatan pengelolaan lingkungan. Hasil penelitian menunjukkan adanya aturan penebangan pohon di kawasan hutan primer, pengelolaan hutan negara untuk kepentingan pemeliharaan bangunan suci dan terdapat aturan jual beli tanaman endemik yaitu rempah-rempah.
NILAI-NILAI FILOSOFIS TRADISI DUEK PAKAT DI GAMPONG TUNONG PAYA KRUEP KECAMATAN DARUL FALAH KABUPATEN ACEH TIMUR
Authors: Hanafiah Hanafiah
Published: October 2021

Philosophical values in society and many social problems occur, as well as the customs that are owned by each Gampong, which has a custom in every social problem and its resolution, including in terms of marrying children (duuk pakat event meukawen), circumcision (sunah rasul ), farming (farming) and solving other problems. This article aims to examine the philosophical values of the tradition of Duek Pakat in Gampong Tunong Paya Kruep in depth, in detail and in full. The results of the study show that the tradition of Duek Pakat is based on a tradition that has been passed down for a long time, namely that Aceh had begun in the era of the kingdom, because the process of duat pakat was a deliberation carried out in the Tunong Paya Kruep Village, Duek pakat also had an impact on promoting deliberation in making decisions and overcoming problems shows that the community likes a peaceful life and tries to avoid conflict, so that the two groups have a very positive impact on the community. The philosophical values contained in the twelfth pakat include: Tradition Values, Cultural Preservation Values, Social Values and Philosophical Values. Masing-masing masyarakat mempunyai adat dalam menyelesaikan setiap permasalahan sosial, termasuk masyarakat gampong di Aceh, di antaranya dalam hal menikahkan anak (duek pakat acara meukawen), sunatan (sunah rasul), bercocok tanam (kenduri blang) dan penyelesaian masalah-masalah lainnya. Artikel ini bertujuan untuk mengkaji nilai-nilai tradisi duek pakat di Gampong Tunong Paya Kruep secara mendalam, rinci dan tuntas. Hasil studi menunjukkan, bahwa tradisi duek pakat didasari dari tradisi turun temurun sejak dari dulu yaitu sudah mulai ada di Aceh pada zaman kerajaan. Proses duek pakat merupakan musyawarah yang dilakukan di Gampong Tunong Paya Kruep. Duek pakat juga berdampak dalam upaya mengedepankan musyawarah dalam mengambil keputusan dan mengatasi masalah menunjukkan bahwa masyarakat menyukai kehidupan damai dan berusaha untuk menghindari konflik, sehingga duek pakat berdampak sangat positif terhadap masyarakat. Nilai-nilai tradisi yang terkandung dalam duek pakat, antara lain nilai tradisi, nilai pelestarian budaya, nilai sosial dan nilai agama.
Perilaku Pencarian Informasi Mengenai Kebijakan Sekolah Tatap Muka oleh Orang Tua Siswa di kota Malang
Authors: Ananda Kun Sila
Published: October 2021

Recently, the Ministry of Education and Culture has established a policy for implementing face-to-face schools. Regarding this policy, students’ parents become a key point in order to make decisions to allow children to attend face-to-face schooling. Before decision making, parents must first reduce uncertainties and lack of information related to the policy. This study discusses the information-seeking behavior of parents related to face-to-face school policies and the decision-making. The method used is descriptive survey. Data collected through online surveys and interviews. The results showed that parents did the active and passive behavior on information seeking. The school (teachers, homeroom teachers, principals, etc.) is the most frequently referred source of information by parents and is considered the most trusted source of information. The most important information needed by parents is regarding the readiness of the school in the implementation of face-to-face learning during the pandemic. In decision-making process, parents often use information sources through online media and discussions with other parents. The majority of parents will delay decision making if the information obtained is deemed insufficient, while on the other hand parents can also experience decision-making failure due to information overload. Belakangan ini Kemdikbud telah menetapkan kebijakan pelaksanaan sekolah tatap muka. Selain akademisi, orang tua menjadi pihak krusial dalam hal ini terutama berkaitan dengan pengambilan keputusan untuk mengizinkan anak mengikuti pelaksanaan sekolah tatap muka. Sebelum mengambil keputusan terlebih dahulu orang tua harus mereduksi berbagai ketidakpastian dan kurangnya informasi terkait kebijakan tersebut. Penelitian ini membahas mengenai perilaku pencarian informasi yang dilakukan orang tua terkait kebijakan sekolah tatap muka hingga proses pengambilan keputusan. Metode yang digunakan adalah survei deskriptif dengan teknik pengumpulan data melalui survei dan wawancara. Hasil penelitian menunjukkan bahwa orang tua melakukan pencarian informasi secara aktif dan pasif. Pihak sekolah (guru, wali kelas, kepala sekolah, dsb) menjadi sumber informasi yang paling sering dirujuk oleh orang tua siswa sekaligus dianggap sebagai sumber informasi yang paling terpercaya. Informasi yang dianggap paling penting oleh orang tua siswa adalah mengenai kesiapan sekolah dalam pelaksanaan pembelajaran tatap muka di masa pandemi. Adapun dalam pengambilan keputusan orang tua seringkali memanfaatkan sumber informasi melalui media daring dan diskusi bersama orang tua siswa lainnya. Mayoritas orang tua akan menunda pengambilan keputusan jika informasi yang didapatkan dirasa belum cukup, sementara di sisi lain orang tua juga dapat mengalami kegagalan pengambilan keputusan karena paparan informasi yang terlalu berlebihan.
Attitudes Towards Blended Learning : A Study of Leadership Training Education (Diklat PIM) IV Year 2018 Training Participants
Authors: Rachman Nadya Megawati , Simamora Caterin Magdalena , Hidayati Ratnaningsih
Published: October 2021

The advancement of information technology is one of the driving factors for implementing e-Government. Nevertheless, the learning process in government official capacity development is now conceivably conducted online. This research aims to discover government officials' attitudes towards blended learning in a population of 40 respondents of Leadership Training Education or   Diklat PIM IV in 2018. This research is conducted with a quantitative methodology approach. The T-test used to test the first research hypotheses. A one-way ANOVA was performed for examining the second and third hypotheses. The result shows there is a favorable attitude towards blended learning among the Diklat PIM IV 2018 training participants. There are significant differences in attitudes toward blended learning based on gender but there is no significant difference in attitudes towards blended learning based on age classification.
KERANGKA KONSEPTUAL UNTUK PENDIDIKAN MULTIKULTURAL DI INDONESIA
Authors: Mahardika Moch. Dimas Galuh
Published: October 2021

Abstrak: Keberagaman yang terintegrasi dalam bingkai Negara Kesatuan Republik Indonesia merupakan suatu hal yang harus menjadi fokus pengamatan dalam konteks pendidikan hari ini. Mengingat negara ini adalah negara yang dihuni oleh berbagai macam suku bangsa, ras dan agama, sedikit banyak menjadi salah satu faktor terjadinya konflik yang berbau SARA, seolah-olah mencederai toleransi atas keberagaman dan perbedaan itu sendiri. Maka pendidikan harus hadir dalam bingkai yang baru untuk mengakomodir pikiran dan pemahaman tentang keberagaman untuk kemudian dapat diajarkan kepada masyarakat. Pendidikan multikultural dapat menjadi salah satu alternatif untuk mengkampanyekan dan membelajarkan keberagaman dalam kerangka pemikiran dan praktik yang lebih konkrit, dengan memberikan pemahaman tentang bagaimana menjalani kehidupan di tengah lingkungan masyarakat yang serba beragam.
Accounting Students’ Academic Performance by Their Background Information
Authors: Sari Siti Antika , Suryani Ani Wilujeng
Published: October 2021

This study aims to determine differences in academic performance of accounting students by their background information. This study involved secondary data from 810 accounting students, analyzed by using Kruskal Wallis test to investigate differences on gender, living environment and funding source. The results show that the academic performance of female students who live at home and obtain scholarship are better than other groups. However, males who live at home and obtain scholarship have indifferent academic performance from other male groups. These findings indicate that gender, living environment and type of educational funding can be taken into consideration to differentiate students’ academic performance. The results of this study can be used by universities to make decisions in determining acceptance criteria, to identify potential students to increase academic performance, and to resolve problems of underperformed students. This research provides an evidence that females and males have different academic performance. Moreover, we found that females who obtained scholarship maintain their high performance, while males are indifferent in their academic performance irrespective of their source of funding
Primary multifocal cystic signet ring neuroendocrine tumor of liver: a case report
Authors: Bansal Nalini , Satapathy Brahmananda
Published: October 2021

Primary signet ring neuroendocrine tumors of the liver are extremely rare tumors. Morphologically, they mimic signet ring cell adenocarcinomas; however, the absence of mucin by special stains and the expression of neuroendocrine markers help to diagnose these tumors. We herein report a case of a 47-year-old female who presented with multiple solid and cystic lesions in both liver lobes, which were initially suggested to be biliary cystadenocarcinoma on imaging. Liver biopsy of the lesion revealed the presence of a signet ring neoplasm with diffuse expression of synaptophysin and pan-cytokeratin. The case was subsequently diagnosed as a primary hepatic signet ring neuroendocrine tumor. The patient was offered 3 cycles of chemotherapy and is well preserved after 14 months of diagnosis. Although this is an extremely rare entity, its possibility should be considered in the differential diagnosis of neoplasms characterized by signet ring cell morphology.
Systemic therapy for advanced hepatocellular carcinoma: consideration for selecting second-line treatment
Authors: Kim Bo Hyun , Park Joong-Won
Published: October 2021

Several molecular-targeted agents have been tested as first- or second-line therapies for hepatocellular carcinoma (HCC) but failed to improve clinical outcomes; sorafenib has been the only approved systemic agent for treating HCC for almost 10 years. Regorafenib resulted in a significant improvement in overall survival and thus was approved for HCC patients previously treated with sorafenib. Subsequently, cabozantinib and ramucirumab demonstrated superior overall survival compared with placebos in phase III clinical trials. Immune checkpoint inhibitors such as nivolumab with or without ipilimumab and pembrolizumab are also available in some countries for patients who are unresponsive to sorafenib. Some second-line agents are available for patients who are unresponsive to sorafenib; however, little is known about the considerations for selecting appropriate secondline systemic agents. Hence, this study aimed to review the current and future perspectives of second-line systemic agents.
Advances in immune checkpoint inhibitors for hepatocellular carcinoma
Authors: Han Ji Won , Park Su-Hyung
Published: October 2021

Hepatocellular carcinoma (HCC) is the fifth most common cancer, and the second leading cause of cancer-related death worldwide. Although recent advances in immune checkpoint inhibitor-based immunotherapy have initiated a new era for advanced HCC treatment, the majority of HCC patients receiving immune checkpoint blockades do not derive clinical benefit. Thus, there remains an urgent need for novel immunotherapeutic strategies with improved therapeutic efficacy. Here we review recent studies of immune checkpoint blockade in HCC, providing the necessary basis for the rational design of immunotherapy.
First Experience of Multifocal and Toric Extended Depth of Focus Intraocular Lenses Implantation (Short-Term Analysis)
Authors: Pershin К. B. , Pashinova N. F. , Tsygankov А. Yu. , Antonov E. A.
Published: October 2021

Aim. Analysis of the functional results of new IOL with an extended depth of focus implantation a in the short-term (6 months) follow-up period.

Patients and methods. The prospective study included 27 patients (40 eyes) after bilateral (n = 12) or monolateral (n = 15) implantation of EDOF IOL Tecnis Symfony with an average follow-up period of 6.5 ± 0.2 (6–7) months. In all cases, IOL implantation was preceded by cataract phacoemulsification or removal of the transparent lens for refractive purposes. The age range was from 39 to 78 (60.6 ± 10.1) years. EDOF IOL Tecnis Symfony ZXR00 was implanted in 30 eyes, and toric EDOF IOL Tecnis Symfony ZXT100, ZXT150, ZTX225, and ZXT300 were implanted in 10 eyes in the presence of clinically significant astigmatism.

Results. An increase in UCNVA from 0.18 ± 0.04 to 0.79 ± 0.11, UCIVA from 0.21 ± 0.07 to 0.89 ± 0.10, UCDVA from 0.24 ± 0.06 to 0.95 ± 0.16, BCNVA from 0.61 ± 0.05 to 0.80 ± 0.03, BCIVA from 0.58 ± 0.10 to 0.97 ± 0.19, and BCDVA from 0.65 ± 0.08 to 1.0 ± 0.06 (p < 0.05 in all cases). The spherical equivalent of refraction decreased from –4.5 ± 1.8 in the preoperative period to –0.18 ± 0.92 in the follow-up period of 6 months after implantation of the Tecnis Symfony ZXR00 IOL. In the group with toric IOLs, a decrease in the cylindrical component of refraction was shown from 1.33 ± 1.02 (modulo) to 0.61 ± 0.44 (modulo) during the maximum observation period. In all cases, the rotational stability of the implanted IOLs was noted. In 9 patients out of 24 (37.5 %), permanent or periodic optical phenomena were detected, of which 4 patients (16.7 %) had halos, 3 (12.5 %) had glare, and 2 (8.3 %) had difficulty driving in the dark. These side effects did not affect the overall patient satisfaction — 22 patients (91.7 %) rated the result of the operation as “excellent”, and 2 patients (8.3 %) — as “good”.

Conclusion. The paper presents an analysis of the first experience in the Russian Federation of implantation of new IOLs with extended depth of focus and their toric version in 27 patients. Data on the effectiveness of this IOL for vision correction at all distances, low frequency of side optical phenomena, and high patient satisfaction are presented. Further comparative studies with other multifocal IOLs are needed.
Tactics of Two-Stage IOL Implantation in Difficult Refractive Cases
Authors: Kasyanov A. A.
Published: October 2021

In a number of complex refractive cases, the achievement of an accurate refractive result cannot be guaranteed. Simultaneous implantation of a toric or multifocal IOL for the correction of complex ametropias may be accompanied by a significant deviation from the target refraction. The tactics of two-stage implantation with the usage of an additional Sulcoflex IOL for the final correction of astigmatism and possible residual spherical ametropia allows achieving emmetropia. In our study, this method was used in 15 patients with difficult refractive cases. Toric, multifocal, and multifocal toric Sulcoflex IOL were used. Implantation of all Sulcoflex modifications was performed through a 2.4 mm temporal incision using wound assisted technology. In cases of high degree hypermetropia, preventive iridectomy was performed using a 23G vitrectome. The target refraction was achieved in the entire observation group. In the postoperative period, no significant level of ophthalmic hypertension was registered. No cases of introlens opacification, iridocyclitis, or rotational instability were registered either.The method of two-stage IOL implantation allows achieving the target refraction in difficult refractive situations with almost guaranteed accuracy. The calculation method provides good predictability of the refractive result. This technology significantly expands the indications for intraocular correction using toric and multifocal IOL, as well as the limits of correction of high degree astigmatism. Our Sulcoflex IOL implantation experience has shown their high efficiency and safety.
Study of State of Interface “Intraocular Lens — Posterior Capsule” Depending on Size of Capsulorhexis in Senile Cataract Phacoemulsification
Authors: Bai Lina , Kolenko O. V. , Egorova A. V. , Vasiliev A. V.
Published: October 2021

Purpose. To study the state of interface “intraocular lens (IOL) — posterior capsule (PC)” depending on diameter of capsulorhexis in phacoemulsification of senile cataract.

Patients and methods. 227 patients (227 eyes) were examined after phacoemulsification of senile cataract at LenSx femtosecond laser (Alcon, USA). The study did not include patients with corneal opacities, signs of axial displacement of lens, with irido- and phacodonesis, glaucoma, axial length less than 22 mm and more than 26 mm. Depending on diameter of performed capsulorhexis, we formed 3 groups: 1st group — 76 eyes with diameter capsulorexis 5.5 mm; 2nd group — 73 eyes with 5.0 mm; 3rd group — 78 eyes with 4.5 mm. We studied type of interface “IOL — PC”, the maximum value of PC diastasis and the maximum depth of its folds using an RTVue-100 Optical Coherence Tomography (Optovue, USA) on the first day after the operation.

Results. The maximum number of eyes with absence of contact between IOL and PC was noted in the 3rd group (62.8 %), the largest number of eyes with full contact between IOL and PC (63.2 %) was in the 1st group. The minimum average depth of the PC folds (111.1 ± 32.7 μm) was noted in the 1st group, and the maximum (165 ± 75.4 μm) — in the 2nd group.

Conclusion. The analysis showed that type of interface “IOL — PC” in the first day after phacoemulsification of senile cataract depends on diameter of capsulorhexis. The largest number of eyes (64.6 %) with full contact between IOL and PC was observed in the group of patients with capsulorhexis 5.5 mm, and the smallest (6.4 %) — in eyes with diameter capsulorexis 4.5 mm. Presumably, the main reason for the absence or incomplete contact between IOL and PC is the presence of viscous dispersive between them. The deformation of PC in the form of folds does not directly depend on diameter of capsulorhexis and, obviously, is due to the uneven tension of the capsular bag by the IOL haptics.
Diabetic Retinopathy. Morphofunctional State of the Retina in Pancreas Recipients
Authors: Vorobyeva I. V. , Moshetova L. K. , Pinchuk A. V. , Bulava E. V. , Lazareva K. E. , Zhuravel N. S.
Published: October 2021

Diabetes mellitus (DM) is one of the most common and rapidly progressing diseases worldwide. Diabetic retinopathy (DR) is a common complication of diabetes and the main cause of vision loss in middle-aged and elderly people. The development and progression of DR is closely related to the duration of diabetes, hyperglycemia, and arterial hypertension. There is growing evidence that inflammation is one of the key links in the pathogenesis of diabetic retinal damage, but the exact molecular mechanisms remain to be known. Pancreas transplantation (PT) is currently the only effective treatment for diabetes that restores normal physiological glucose metabolism. Due to the limited number of PT surgeries associated with the severity of intra- and postoperative complications and the acute issue of organ donation, studies on the assessment of DR after PT are few and contradictory. There is a need for further studies of the DR state after PT with the study of the influence of risk factors, determination of the level of immunological markers and the use of modern instrumental research methods to create effective patient management regimens in the postoperative period.
Reduced Quality of Life in Elderly Patients with Glaucoma
Authors: Agarkov N. M. , Chukhraev A. M. , Fabrikantov O. L. , Yablokova N. V.
Published: October 2021

Glaucoma is the most severe eye disease that leads to irreversible blindness, and is a widespread pathology among the population of different countries and especially in the elderly. The urgency of the problem increases in connection with the demographic processes occurring in industrial countries, characterized by aging of the population. The development of glaucoma in the elderly exacerbates the image and quality of life of these patients, which must be taken into account in the implementation of medical and social and specialized ophthalmological care. However, the study of the quality of life in elderly glaucoma patients by a specific questionnaire was not carried out.

The purpose: to analyze the quality of life of elderly patients suffering from glaucoma for a long time.

Material and methods. The study of quality of life was carried out in the Tambov branch of the S. Fyodorov Eye Microsurgery Federal State Institution. In clinical conditions, a survey of 228 patients with glaucoma aged 60–75 years, who made up the main group. The survey was conducted on a special questionnaire-National Eye Institute Visual Functioning Questionnaire among patients of the above group by direct interviewing. The results were integrated into 122 scales for processing and analysis in accordance with the requirements of this questionnaire. Similarly, for comparison, the quality of life was studied in 178 patients of the same age with no history of glaucoma and at the present time. In assessing the quality of life, arithmetic averages and their errors were calculated, and the nonparametric t-white criterion was used to determine the reliability of the differences.

Results. It was found that the development of glaucoma in the elderly causes a significant decrease in the quality of life on all scales of the questionnaire, reflecting the specific manifestations due to visual impairment. At the same time, the most pronounced effect of glaucoma has on the reduction of distant vision — 19.5 ± 1.3 points against 69.5 ± 1.8 points (p < 0.001) in the control group. The defeat of glaucoma leads to a significant decrease in the quality of life of elderly patients and other indicators. In the main group, the overall score of vision (23.5 ± 1.5 points vs. 75.2 ± 1.9 points in the control), near vision (26.8 ± 1.6 points vs. 73.5 ± 2.0 points in the control), high dependence on outsiders in solving everyday problems (30.5 ± 1.6 points vs. 79.3 ± 1.8 points in the control) were significantly lower. To a lesser extent, with the development of glaucoma, color perception suffers.

Conclusion. The analysis of the quality of life in elderly patients with glaucoma is of practical importance for the organization of an individual treatment and prevention plan, since it takes into account the opinion of each patient about the perception of the disease.
Recurrent Keratoconus. Clinical Case
Authors: Konovalov M. E. , Burdel K. V. , Zenina M. L. , Reznikova A. B. , Konovalova M. M.
Published: October 2021

Purpose: To provide a clinical case of recurrent keratoconus from our practice.

Materials and method. A patient came to the clinic with a complaint of decreased visual acuity in the right eye. A series of standard instrumental examinations and Scheimpflug keratotopography were performed, and astigmatism of the right eye was diagnosed. Similar examinations were carried out during the patient’s attendance at follow-up examinations.

Results. Based on the results of scanning Scheimpflug keratotopography, the diagnosis of keratoconus (forme fruste) was made. On examination after 1 year, there were no complaints of decreased visual acuity and data from the same instrumental examinations indicating keratoconus. After this examination, the patient came 3.5 years later with complaints of a new decreased visual acuity in the right eye. During instrumental examinations and keratopography, data were obtained indicating the presence of posterior keratoconus. After 1 year, a follow-up examination took place without complaints. The data of instrumental studies are identical to the previous visit; keratotopography revealed a decrease in posterior elevation.

Discussion and conclusion. It was revealed that the patient was constantly taking the hydroxyurea drug against the background of systemic disease up to the 3rd visit, at the time of the 4th visit she had not taken it for 1 year. There are publications in the literature on the effect of this type of drugs on the collagen of the dermis of the skin, the type of which corresponds to the collagen of the cornea. We hypothesize that drugs may have an effect on the biomechanical properties of the cornea, which requires further in-depth study.
Implementation of an Oncofertility Program: Key Elements, Challenges, and Solutions of the Oncofertility Treadmill
Authors: Hussain Anisa , Sehring Jacqueline , Usmani Safina , Grimm Lauren , Abadi Ahmad , Beltsos Angeline , Jeelani Roohi
Published: October 2021

An overwhelming proportion of females of reproductive age are affected by cancer annually. As the efficacy of cancer treatments increases the number of cancer survivors, it is imperative to ensure that the fertility-related needs of cancer survivors are met. Given the gonadotoxic nature of many cancer treatments, fertility preservation for patients prior to cancer treatment, Oncofertility, is a critical area of reproductive care. The establishment of an Oncofertility program requires swift and effective patient care that relies heavily on collaboration between multiple specialties, patient education, and clear treatment protocol. This specific flow of patient care can be referred to as an “Oncofertility treadmill,” given the emphasis on efficiently completing ovarian hyperstimulation cycles so that the patient may proceed with cancer treatment. We began by identifying key steps in the establishment of an Oncofertility program at a private, multisite fertility clinic, then explored the challenges that providers and patients may face, and the outcomes of Oncofertility patients undergoing ovarian hyperstimulation with the intention of oocyte cryopreservation. Oncofertility care is complex and the establishment of concrete guidelines for this Oncofertility care will greatly benefit cancer survivors.
A Historical Perspective on Endocrine Disruption as an Emerging Multifaceted Medical Problem
Authors: Darbre Philippa
Published: October 2021

This historical perspective outlines how advances in endocrinology are uncovering mechanisms by which environmental chemicals may interfere in the synthesis and actions of hormones. Such chemicals have been termed endocrine disrupting chemicals (EDCs). Advances in understanding of receptor-mediated genomic and non-genomic actions of hormones have demonstrated the ability of EDCs to compete with hormone for binding to receptors in target cells and thereby to either mimic or antagonise hormone action. Advances in development of a range of assays for identifying endocrine activity of environmental chemicals have led to an appreciation of the wide distribution of EDCs to which the human population are now exposed in air, water, food and consumer products. Technological advances for measuring EDC concentrations in human tissues have demonstrated their widespread presence in human urine, blood, milk, adipose tissue, placenta and breast. Advances in understanding of the wide-ranging physiological effects of hormones and underlying defects in endocrine disorders have begun to reveal how EDCs may provide a new dimension to endocrine dysfunction. Evidence is accumulating for a role of EDCs in many male and female reproductive disorders, thyroid and adrenal disorders, immune system dysfunction and metabolic disorders including obesity, diabetes and cardiovascular disease. Deregulation of hormonally controlled cell growth may contribute to development of endocrine cancers. Adverse effects of EDCs on developmental processes, including neurodevelopment, have implications for child health and for appearance of disorders not only in later adult life but also into future generations.
The in vitro multiplication of anthurium cv. Eidibel
Authors: Barros de Lima Isabelly Maria , Campos Arlene Santisteban , Portugal Pinto de Carvalho Ana Cristina
Published: October 2021

Anthurium is one of the most marketed species in international floriculture. The availability of sufficient plants of phytosanitary quality is a limiting factor in their commercial cultivation. Micropropagation is the most common technique used in producing plantlets on a large scale. The aim of this study was to determine the most suitable relationship between growth medium, BAP concentration and photoperiod for increasing the in vitro multiplication rate of the ‘Eidibel’ cultivar. A completely randomised design was used in a 2 x 9 x 2 factorial scheme with 20 replications. The treatments comprised combinations of two types of growth medium (MS and Pierik), nine concentrations of BAP (0.0; 1.11; 2.22; 3.33; 4.44; 5.55; 6.66; 7.77 and 8.88 μM), and two photoperiods (12 and 16 h). The number of shoots per explant (NSE) and percentage of explants forming organogenic calli (FOC) and roots (FR) were evaluated after 60 days. The highest values for NSE, 3.66 and 4.69, were obtained in the MS and Pierik growth media, containing 8.88 μM and 4.85 μM BAP respectively. The NSE was higher under the 12-hour regime in the MS medium, and equal under the two photoperiods in the Pierik medium. The lower the BAP concentration, the greater the percentage of root formation and the smaller the percentage of organogenic calli. The Pierik medium is recommended for the production of micropropagated ‘Eidibel’ plantlets, with the addition of 4.85 μM BAP, under a photoperiod of 12 h.
Salinization at the mouth of the São Francisco River: impacts on the Potengi community, Alagoas, Brazil
Authors: Vital Filho João Luís , Santos Denise Souza , Correia Martins Carla Maria , Silva Ricardo Barros , Correia Martins Gleica Maria
Published: October 2021

The salinization process at the mouth of the São Francisco River has been caused serious damage to the ecosystem and the quality of life among riverine populations. This study aimed to assess the perception of the riverine populations regarding the effects of water salinization at the mouth of the São Francisco River, and also to analyze the quality of water that is provided to the Potengi community in Piaçabuçu, Alagoas, Brazil. For data collection, semi- tructured interviews were conducted with 22 riverine residents. The analyses of water samples were carried out at four places in the community, in which analyzes of pH, electrical conductivity, determination of salinity, and turbidity of the water were made. It was possible to identify, during the performance of this study, the inefficiency of the public authorities, both concerning the informative and mitigating actions, as the exposure of the population to high levels of sodium and turbid water, leading to changes in the parameters concerning data established by the World Health Organization (WHO). The results revealed that one of the samples analyzed presented a saline level 17 times higher than the limit established by the WHO, and a turbidity index was 15.6 times higher than the technical limit established. Therefore, these changes have affected the health of the community, directly compromising the use of water and the composition of the biota in the region.
Physiological seed quality in cultivars of the carioca bean produced in the North of São Paulo and kept under storage
Authors: Pinto Carolina Cipriano , Da Silva Juliano Costa , Do Amaral Camila Baptista , E Oliveira Carina Oliveira , Araújo Flôres Jordana De , Lemos Leandro Borges
Published: October 2021

New bean cultivars, in addition to having high productivity, should meet requirements regarding the physiological attributes of the seeds, maintaining them during storage, minimising their deterioration and guaranteeing the producer a crop that is quickly and uniformly established. The aim of this study was to evaluate the physiological attributes of the seeds of thirteen bean cultivars (Phaseolus vulgaris L.) from the carioca commercial group, produced during the winterspring harvest in the North of the state of São Paulo, at two different times: after harvest and during the eighth month of storage. The experimental design was completely randomised, in a 13 x 2 factorial scheme with four replications. The factors corresponded to the 13 carioca bean cultivars (Pérola, BRSMG Majestoso, BRS Estilo, BRSMG Madrepérola, IPR Campos Gerais, IPR Tangará, IPR Andorinha, IPR 139, IAC Imperador, IAC Formoso, IAC Alvorada, IAC Milênio and Bola Cheia) and two periods of evaluation (0: after harvest and 8: eight months after harvest). Each of the cultivars under study displayed physiological qualities that were within the required standards after harvest. The BRS Estilo, BRSMG Madrepérola, BRSMG Majestoso, IAC Imperador
and IPR Andorinha cultivars maintain germination within these standards after eight months of storage. The seeds of the IAC Imperador cultivar show greater vigour than those of the other cultivars when produced during the winter-spring harvest in the North of the state of São Paulo.
Phenotypic diversity of bacteria in root nodules of Dalbergia ecastaphyllum (L.) Taub. (Fabaceae)
Authors: Carmen Trujillo Pacheco Lidia Del , Costa Jônatas Oliveira , Barros Prado Moura Flávia De , Lima Bezerra José Jailson , Do Nascimento Prata Ana Paula
Published: October 2021

Many species belonging to family Fabaceae are able to establish symbiotic relationships with nitrogen-fixing bacteria. Studies developed with Dalbergia ecastaphyllum (L.) Taub., for example, have demonstrated the symbiotic potential of this species. In this sense, this study aimed to analyze the phenotypic characteristics of rhizobia isolated from D. ecastaphyllum and to identify whether these bacterial isolates are capable of establishing symbiotic relationships with Vigna unguiculata (L.) Walp. D. ecastaphyllum seeds were sown in soil samples collected in Japaratinga, Alagoas, Brazil, in three zones located at different distances from the high tide line. At 60 days after the emergence of the plants, nodulation in the roots of D. ecastaphyllum was analyzed and the bacteria were isolated. Subsequently, the phenotypic characterization of the bacteria was carried out based on some criteria (growth time, type of pH, colony color, type of mucus and amount of mucus). For the nodulation test, the species V. unguiculata was used. In total, 17 phenotypic types of bacterial isolates were identified, of which 8 are fast-growing and 9 are intermediate-growth. Regarding the type of pH, 7 phenotypes are acidic pH, 8 are neutral pH and 2 are alkaline pH. As for the coloring of the bacterial colonies, 5 are yellow, 7 white and 5 pink. It was also observed the presence of consistent and aqueous mucus in colonies from the three different areas. Only 7 bacterial phenotypic types and the commercial inoculant were efficient in the nodulation of V. unguiculata.
A study of psoas minor muscle morphology
Authors: Simhadri Deepthi , Navakalyani T , Suseelamma D
Published: October 2021

Psoas minor is long, slender skeletal muscle it lies anterior to psoas major. It is an inconstant muscle. It was absent in 40-70% of subjects.

To determine the frequency and morphometry of psoas minor muscle.

: 20 cadavers were dissected during routine dissection for undergraduate students at Ayaan institute of medical sciences, Moinabad, Hyderabad and Government medical college, Mahabubnagar.

Bilateral variations were observed in one specimen, unilateral variations were observed in two specimens.

: Out of forty specimens Psoas minor was present in three specimens. In one specimen bilateral variations observed, other two specimens unilateral. If it is present, clinical importance to radiologists, surgeons and physiotherapists as it can mimic certain abdominal emergencies.