bluuebunny/crossref_metadata_2025 huggingface dataset:
Scythian Burials: The Problem of Localization of the Royal Mounds
Authors:   L. N. Gumilyov Eurasian National University, Gulnar T. Kazhenova , Lubomir S. Dobrovolskiy ,   L. N. Gumilyov Eurasian National University
Published: July 2021

The localization of the Scythian Gerros is still completely uncertain. The problems associated with it cover a wide range of currently unresolved topical issues due to both the state of preservation of rich burials and the lack of clear criteria for their definition, in particular, social ranking, i. e. issues related to the identification, number and location of the royal mounds. The study is based on the logic of the general scientific inductive and deductive method as the conceptual core of obtaining the initial and inferred knowledge about the object of our research – the localization of the mounds of the Scythian kings, the subject of which is the general cultural and archaeological signs of the Scythian kings’ mounds. We have come to the conclusion that the use of craniological studies of anthropological material from burial monuments located within the Scythian “square” of Herodotus, for their proximity to the Tuvan Okunevians will firstly allow us to identify and select the royal Scythians from the entire massif of Scythian material, then subsequent mapping of the data will make it possible to determine the area of their settlement. Secondly, with the help of craniological analysis, it will be possible to determine the burials of the Scythian kings, which should contain homogeneous anthropological material within the same burial room. Thirdly, in the process of searching for Scythian burials outside the steppe, we will also be helped by craniological studies of material that was not initially classified as “Scythian” due to the lack of clear criteria for its selection. Fourthly, the mapping of the burials of the royal Scythians and the systematization of all the signs of groups located in the same vector of their closest ties will bring us closer to solving an even more extensive problem – the definition of the concepts of “Scythian”, “Scythian culture” and “Scythian archaeological culture”. Keywords: Gerros, mound, localization, Scythian kings’ mounds, royal Scythians
Forms of Legitimization in the Russian Empire
Authors:   Transbaikal State University, Inna N. Mamkina
Published: July 2021

The article is devoted to a comprehensive study of the legitimization forms in the Russian Empire. It also presents the idea of inextricable connection between the understanding of a historical event or phenomenon and the socio-political processes reflected in law. Therefore, the understanding of the Imperial law system, the insight into the peculiarities and processes of its legitimization formation is the basis of historical studies of the Russian Empire period. The purpose of this paper is to summarize and to give the comparative analysis of the legitimization forms existing on the territory of the Russian Empire and its outskirts in the period of the 18th ‒ early 20th centuries. The methodological basis of the study is a set of historical and legal methods used in the state-legal phenomena study. The study uses the comparative-historical, terminological analysis and comparative law methods. The paper is interdisciplinary, it is written at the intersection of jurisprudence and historical science. The study found a variety of legitimization forms enshrined in Russian Law, which are difficult to classify. It was noted that the classification and hierarchy of Russian Legislation depended on the extent of the monarch’s involvement in the legislative process. The author draws attention to the fact that the legitimization within the spatial and personal scope has some features that are most pronounced toward Siberia. When analyzing the content of a number of Charters and Provisions, specific standards or exemptions regarding this act enactment on the Empire outskirts are often found. The organization of power on the national Empire outskirts was regulated by special acts. The author concludes that despite the variety of legislative forms the Emperor’s will remained above the law and the law-making mechanism provided for its legal confirmation forms. Indeed, from a legal standpoint, such acts weakened the strong arm and the rule of the law, on the other hand, they speed up some decision-making processes. Keywords: the Russian Empire, Siberia, System of Law, sources of Law, form of Law, legislation, autocracy
The NKVD of the Far East in the Fight Against Child Homelessness and Neglect (1941–1945)
Authors:   Vladivostok Branch of the Far Eastern Law Institute of the Ministry of Internal Affairs of Russia, Alexander V. Zhadan
Published: July 2021

The problem of child homelessness and neglect in the USSR became one of the grave socio-economic consequences of the Great Patriotic war. These phenomena, instilling in children the skills of antisocial behavior, contribute to the criminalization of the younger generation, the degradation of future labor resources. This publication, based on documentary sources, a significant part of which is introduced into scientific circulation for the first time, aims to analyze and summarize the historical experience of the NKVD of the Far Eastern region in the fight against homelessness and neglect in wartime conditions. The author solves the following problems: analysis of factors contributing to the sharp increase in the phenomena under consideration during the war in the Far East; characteristics of organizational forms and methods used by the NKVD in order to combat child homelessness and neglect; research of the reasons that negatively affected the effectiveness of the internal affairs bodies in this direction. The research uses the principles of historicism, objectivity and consistency, as well as general scientific and special methods of historical science. As a result of the study, it is concluded that the Far Eastern NKVD bodies were able to achieve significant success by the end of 1945 in countering homelessness, neglect and child crime, however, for a number of objective reasons, they were not able to completely neutralize the negative impact of these phenomena on the Far Eastern society, which affected the level of its criminalization in subsequent years. Organizational forms and methods of combating child homelessness and neglect evolved during the war years, responding to the aggravation of the nature of the problem. In the organizational structure of the NKVD bodies, such elements as departments for combating child homelessness and neglect, children’s rooms of the police, labor educational colonies for minors appeared; interaction with the active public of the region was intensified. Keywords: Far East; children’s police rooms, NKVD receivers and distributors; NKVD bodies, World War II; homelessness and neglect
Artistic Work of Polish Exiles in the Trans-Baikal Region of Russia in the Second Half of the 19th Century
Authors:   East-Siberian State Institute of Culture, Evgeniy V. Semenov
Published: July 2021

Polish political exiles to Siberia of the latter half of the 1800s were involved in many aspects of the social and cultural life of the time in the Trans-Baikal Region of Russia. However, in contrast to their scholarly research conducted while in exile, their artistic activities have never been a topic of independent studies. The objective of this paper is to study artistic work of Polish exiles in the context of penal labor and penal settlements. When developing the topic of this study, the author relied on fundamental research principles and methods. Using a broad range of archive materials and private sources, the author describes the artistic journeys of the most famous Polish artists in exile who left a prominent legacy in the Trans-Baikal artistic life of the time. When working on the topic of the article, the author used the following methods of historical research: analysis of written sources, bibliographic method, historical and genetic method. While being formally convicted to penal labor in the mines and factories of Nerchinsk mining region, some Polish exiles were not actually required to engage in hard labor. The most artistically minded among them were looking for the opportunities to selfeducate themselves and engage in artistic activities. The author identified several previously unknown facts associated with the artistic legacy of Polish exiles. Against the backdrop of Polish deportation in the 1800s, the author reconstructed the artistic work of Jozef Baerkman and Stanislaw Wronski. During their time in the Siberian penal system, Polish artists created paintings, taxidermic works, and illustrations to the scholarly works of Benedykt Dybowski. However, their most active creative period began when they were released from hard labor and settled in penal colonies. Today, some works of Polish artists in exile created during the second half of the 19th century are part of collections of regional museums. Keywords: Polish exiles, Polish artists, artistic activity, Trans-Baikal region, Stanislaw Wronski, Jozef Baerkman
Journey from Krasnoyarsk to Moscow in 1923
Authors:   Krasnoyarsk State Agrarian University, Svetlana V. Bershadskaia
Published: July 2021

By examining the personal journal of Marfa Solov’eva, one of the staff of Krasnoyarsk Local History Museum (Yenissei Province), the article aims to analyze some changes of everyday life at the beginning of the 1920s. Aged 33, Ms. Solov’eva found herself among the members of the Yenissei Province delegation sent to participate in the First All-Union Agriculture and Orchard Industry Exhibition in Moscow in 1923. She wrote down her personal experiences of travelling from Krasnoyarsk to Moscow. Given that anthropological shift has taken the lead in historical research, the materials of personal origin (like personal journals) provide an additional avenue to get firsthand information on how contemporaries interpreted the turning points in history. By focusing on the findings from the personal journal introduced for the first time the article investigates the transformations in early Soviet society at the grassroots level and from the point of view of a young representative of Siberian intelligentsia. The article demonstrates how day-to-day and leisure practices of those who took part in the trip were organized. Additionally, it considers the emotional sphere, which is missed to a greater extent by official sources. A mixture of interdisciplinary, systematic and sociocultural approaches and descriptive methods for interpreting sources has been adopted. Keywords: personal journal, everyday life, the intelligentsia, Siberia, the Yenissei province, the onset of NEP, the First All-Union Agriculture and Orchard Industry Exhibition in Moscow in 1923
Tver Zemstvo and Governor A. N. Somov: Features of Interaction
Authors:   Tver State University, Aleksei E. Andreev
Published: July 2021

The article analyzes the interaction of the Tver governor A. N. Somov with zemstvo institutions at the end of the 19th century. The issue of interaction between authorities and local self-government, independent from each other in accordance with the current legislation, is relevant for the work of both representative and executive authorities in the Russian Federation. The aim of the study is to determine the features of the interaction of the Tver zemstvo and the highest official of the province at the end of the 19th century. The author’s methodological approaches are traditionally determined by the principles of scientific objectivity, historicism and historical determinism. The study used both universal scientific methods and special methods of historical research, determined by the specifics of the problem posed and source material, namely: problem-chronological method, comparative analysis method, systemic method. The source base of the research is quite representative and included several groups of historical sources: legislation, office documentation, official directories, periodicals. In the course of the study, it was revealed that an employee exiled from the capital for anti-government activities worked in the provincial zemstvo statistical committee. With his help, the Zemstvo people provided the governor, and he, in turn, with the Ministry of Internal Affairs, inaccurate information in order to reduce the police apparatus. Another example of the governor’s benevolent attitude towards the anti-government-minded zemstvo is the submission to the Ministry of Internal Affairs of the dissenting opinion of the provincial zemstvo assembly on the shortcomings of state power and the need to reform the state apparatus. The facts of the reaction of the Governor of Tver A. N. Somov on the actions of the Tver zemstvo confirm the opinion about the anti-government activities of the zemstvo, which for more than 20 years was not suppressed in a timely manner by this governor, despite the latter’s significant powers. Keywords: zemstvo, governor A. N. Somov, provincial institutions, anti-government work
Perkembangan Dakwah Muhammadiyah di Tombolo Pao Kabupaten Gowa
Authors: Rifai Imran
Published: July 2021

Muhammadiyah sebagai salah satu organisasi masyarakat keagamaan memiliki misi melakukan perubahan dalam kehidupan umat Islam kepada kondisi yang lebih baik. Melalui strategi amar ma’ruf nahi munkar sebagai dasar gerakan, Muhammadiyah bertujuan untuk memurnikan kembali ajaran Islam yang banyak dipengaruhi oleh hal-hal mistis. Termasuk yang terjadi di Kecamatan Tombolo Pao, keadaan masyarakat masih dipengaruhi oleh kepercayaan animisme dan dinamisme dengan praktik-praktik ibadah yang penuh dengan bid’ah, khurafat, takhyul dan syirik. Seiring dengan berdirinya Muhammadiyah, perlahan tapi pasti selalu memberikan bimbingan dan pencerahan dengan metode dakwah berdasarkan Al quran dan Hadis. Jenis penelitian ini menggunakan metode kualitatif, teknik analisis data yakni pengumpulan data, reduksi data, penyajian data dan penarikan kesimpulan. Tulisan ini fokus pada sejarah berdirinya Muhammadiyah serta pengaruh pemikiran dakwah Muhammadiyah di Kecamatan Tombolo Pao Kabupaten Gowa.  Implikasinya, dakwah yang dilakukan Muhammadiyah melalui berbagai sektor dan sasaran dakwah bisa dianut oleh organisasi masyarakat keagamaan lainnya, supaya diterima kalangan masyarakat luas seperti halnya yang terjadi di Tombolo Pao.***Muhammadiyah as one of the religious community organizations has a mission to make changes in the lives of Muslims to a better condition. Through the strategy of amar ma'ruf nahi munkar as the basis of the movement, Muhammadiyah aims to purify the teachings of Islam which are heavily influenced by mystical things. Including what happened in Tombolo Pao District, the condition of the community is still influenced by animistic beliefs and dynamism with worship practices that are full of heresy, superstition and shirk. Along with the establishment of Muhammadiyah, slowly but surely always provide guidance and enlightenment with da'wah methods based on the Qur'an and Hadith. This type of research uses qualitative methods, data analysis techniques, namely data collection, data reduction, data presentation and drawing conclusions. This paper focuses on the history of the founding of Muhammadiyah and the influence of Muhammadiyah's da'wah thought in Tombolo Pao District, Gowa Regency. The implication is that the da'wah carried out by Muhammadiyah through various sectors and targets of da'wah can be embraced by other religious community organizations, so that it is accepted by the wider community as happened in Tombolo Pao.
Dakwah Aisyiyah melalui kader Tuberkulosis (Tb) care di Kabupaten Sinjai
Authors: Hasmiati Hasmiati , Rita Rita , Amiruddin Amiruddin
Published: July 2021

Islamic da'wah is carried out in all sectors, including health. Likewise, Tuberculosis (TB) Care Aisyiyah in Sinjai Regency. The purpose of the study was to determine the form of Aisyiyah preaching through TB Care cadres. This type of research, qualitative, data collection using the method of observation, interviews and documentation. Data analysis applied in this study started from data collection, data reduction, data presentation and drawing conclusions. The results showed that Aisyiyah preaching through TB Care cadres started from mentoring. Assistance of TB Care cadres is carried out periodically, the first visit is called sampling and becomes a discussion partner with patients, and patients' families starting from information on treatment, healing and health (starting from monitoring taking medication for a period of six months to the recovery stage). Furthermore, the form of da'wah carried out by TB Care cadres in broadcasting da'wah through three forms, namely da'wah by oral bill, da'wah bil hal and da'wah bil qalam. The implication of this research is that the delivery of da'wah for TB Care cadres should be optimized by providing knowledge related to da'wah for TB Care cadres.***Dakwah Islam dilakukan di semua sektor, termasuk kesehatan. Begitu juga yang dilakukan oleh Tuberculosis (TB) Care Aisyiyah di Kabupaten Sinjai. Tujuan penelitian untuk mengetahui bentuk dakwah Aisyiyah melalui kader TB Care. Jenis penelitian, kualitatif, pengumpulan data menggunakan metode observasi, wawancara dan dokumentasi. Analisis data yang diterapkan dalam penelitian ini mulai dari pengumpulan data, reduksi data, penyajian data dan penarikan kesimpulan. Hasil penelitian menunjukkan bahwa dakwah Aisyiyah melalui kader TB Care dimulai dari pendampingan. Pendampingan kader TB Care dilakukan secara berkala, kunjungan pertama disebut dengan pengambilan sampel serta menjadi mitra diskusi terhadap pasien, dan keluarga pasien mulai dari Informasi pengobatan, kesembuhan dan kesehatan (mulai dari pengawasan minum obat selama kurung waktu enam bulan sampai pada tahap kesembuhan). Selanjutnya bentuk dakwah yang dilakukan oleh kader TB Care dalam menyiarkan dakwah melalui tiga bentuk, yakni dakwah secara bil lisan, dakwah bil hal dan dakwah bil qalam. Implikasi penelitian ini bahwa  penyampaian dakwah kader TB Care hendaknya dioptimalkan dengan memberikan pengetahuan terkait dakwah terhadap kader TB Care.
AMINO ACID STATUS OF BOVINE MILK UNDER SEASONAL VARIATION AROUND SINGRAULI DISTRICT
Authors: PATEL RAJESH K. , SINGH P. K. , PANDEY RAJESH , PATEL BABBULAL , MISHRA SANDEEP
Published: July 2021

Objective: The present work deals with the concerned study to determine the influence of variable season on amino acid evaluation from 90 bovine milk collected (March 2018 to February 2019) samples belongs to four tehsils of Singrauli district.
Methods: An aliquot of hydrolysate of collected bovine milk samples were injected into the column (Shim-pack ISC-07/S1504 Na) of the higher performance liquid chromatography-based amino acid analyzer.
Results: Most abundant amino acids were glutamic acid followed by proline and leucine. Average amino acid content comparison, results, in the rainy season, maximum amino acid content was in Deosar and minimum in Singrauli, In winter amino acid is higher in Waidhan and minimum in Deosar and maximum amino acid content was recorded intended for Waidhan and minimum for Deosar in summer. Concentration of amino acid in cow milk was found to be in order of glycine<histidine<alanine<methionine<isoleucine<phenylalanine<threonine<tyrosine<serine<lysine<valine and aspartic acid<arginine<leucine<proline<glutamic acid. Amino acid status in buffalo milk sample was found in order Glycine<histidine<methionine<alanine<phenylalanine<isoleucine<threonine<arginine<tyrosine<serine and lysine<aspartic acid<valine<leucine<proline<glutamic acid. All the amino acids are evaluated as per the mean (n = 6) mean±SD.
Conclusion: It is concluded that cow and buffalo milk samples contained all the amino acids but differed in the contents of certain amino acids. Such variation is purely biological and genetic and is intended for the nourishment of the young. The current investigation would be valuable for the dairy processing industries to formulate nutritionally improved milk-based functional products for a vulnerable segment of the population.
Nutritional Assessment Stage 3 Chronic Kidney Disease
Authors: Adair Kathleen E. , Heileson Jeffery L. , Peterson Matthew N. , Bowden Rodney G. , Forsse Jeffrey S.
Published: July 2021

Objective: Dietary guidelines from the Kidney Disease Outcomes Quality Initiative (KDOQI) and the United States Department of Agriculture (USDA) are advised to individuals with mid-spectrum (stages G3a and G3b) chronic kidney disease (CKD), yet typical diets in individuals with CKD remain understudied. The purpose of this study is to assess the self-reported dietary pattern of subjects with diagnosed mid-spectrum CKD and compare the normal dietary intakes to the KDOQI and USDA recommendations.

Methods: A cross-sectional analysis of 20 participants with mid-spectrum CKD (n = 6 male [M]; n = 14 female [F]) was conducted to assess subjects’ self-reported dietary intakes for an average of 5 days. Micro and macronutrient analyses were compared to the KDOQI and USDA guidelines by sex to assess nutrition, and an exploratory stepwise multiple linear regression model was used to identify predictors of poor renal function;p-values were considered significant at the α = 0.05 level.

Results: All subjects met the recommended caloric intake, but the average consumptions of protein (F = 0.86 ± 0.29g/kg body weight/day, M = 1.18 ± 0.45g/kg body weight/day), saturated fat (F = 12.17 ± 2.28%, M = 13.86 ± 1.20%), and sodium (F = 3.78 ± 2.51g, M = 4.21 ± 0.39g) were high (p < 0.05 for all). The average fiber intakewas low (F = 13.64 ± 4.09g, M = 14.82 ± 7.28g) as well as folate, vitamins D and K, zinc, and calcium intakes compared with the recommendations (p < 0.05 for all). The only significant contributor to higher renal function in the exploratory regression analysis was male sex (p = 0.035).
Hemoperfusión con dispositivo CytoSorb en paciente con COVID-19
Authors: Mercado Ferrer César , Rey Vela Emilio , Rico Fontalvo Jorge , Daza Arnedo Rodrigo , Pájaro Galvis Nehomar Eduardo , González Greisy , Gómez Ayala Jaime , Leal Martínez Victor , Abuabara Franco Emilio , Pomares Lara Alonso , Pérez Calvo Christian , Raad Sarabia María
Published: July 2021

La enfermedad COVID-19 es una enfermedad infecciosa ocasionada por el virus SARS-CoV 2 cuya presentación clínica es muy heterogénea: puede ir desde personas asintomáticas hasta pacientes críticamente enfermos, con tormenta de citoquinas, distrés respiratorio agudo, disfunción de órganos e incluso la muerte. Las terapias actuales para su tratamiento van encaminadas a reducir el impacto de la cascada inflamatoria, y dentro de estas encontramos las tecnologías de hemoadsorción como la membrana CytoSorb. A continuación, presentamos un paciente masculino de 31 años de edad, quien consultó por sintomatología severa de COVID-19 y mostró una evidente mejoría clínica y bioquímica posterior al uso del dispositivo CytoSorb. Este es el único paciente documentado en Colombia al que se le haya realizado terapia de hemoperfusión con este dispositivo en conjunto con terapia de reemplazo renal intermitente prolongada y se hayanregistrado desenlaces clínicos favorables.
Enfermedad mano pie boca en adultos inmunocompetentes. Serie de casos
Authors: J R Brusa , M N Andrade , V E Rossello , V R López Gamboa , M S Gómez Zanni , A Guidi , M B Del Valle Papa
Published: July 2021

Resumen

La Enfermedad mano pie boca es una patología exantemática viral muy contagiosa, de predominio en la edad pediátrica. Sus agentes etiológicos más frecuentes son los virus Coxsackie y Enterovirus. Se caracteriza clínicamente por la presencia de fiebre, erosiones en mucosa bucal y exantema máculo vesicular en regiones acrales. Generalmente se autolimita, pero puede presentar complicaciones severas con compromiso neurológico, pulmonar y cardíaco. Se han observado brotes mundiales, por lo que actualmente es considerada un problema de salud pública emergente, tanto en poblaciones pediátricas como adultos. Se presentan casos de pacientes adultos inmunocompetentes con transmisión intrafamiliar de Coxsackie B, sin complicaciones severas. Estos casos muestran la importancia de la prevención para evitar brotes epidémicos, además de destacar la presentación infrecuente en adultos inmunocompetentes.
A novel predictive model of recurrence after surgical ablation of valvular atrial fibrillation
Authors: Wang Yali , Tang Xinlong , Ailiya Adili , Xu Can , Zhu Xiyu , Jiang Yi , Xue Yunxing , Fan Fudong , Cao Hailong , Pan Jun , Zhou Qing , Wang Dongjin
Published: July 2021

Background: Radiofrequency ablation(RFA) has emerged as a common
approach to treatment of atrial fibrillation(AF) coupled with valve
surgery. However, risk factors were rarely reported on recurrence after
RFA of valvular atrial fibrillation . Methods: Retrospective study of a
single-center database was performed in patients underwent valvular
surgery combined with radiofrequency ablation. Follow-up was conducted
from 3 months to 1 year after procedure. AF recurrence was defined as
any episode of atrial arrhythmia lasting more than 30 seconds. Risk
factors were analysis using Logistic regression and a predictive model
was established. Results: 3-month follow-up was completed in 319
patients, 195 patients (61.1%) had AF recurrence. During the 1-year
follow-up, 74 /166 patients(44.6%) had AF recurrence. Compared with
sinus rhythm maintenance group, overweight(p=0.022), high BMI(p=0.024),
large preoperative LAD(p<0.001), small MI area(p=0.019), large
MI diameter(p<0.001) and other liver function parameter like
low ALT level(p=0.023), high total bilirubin(p=0.013) and direct
bilirubin level(p=0.033) were significantly correlated with AF
recurrence after RF. In multivariate analysis, BMI(OR 1.12, 95% CI
1.04-1.21, p=0.003), LAD(OR 1.49, 95% CI 1.09-2.07, p=0.015), MI
area(OR 0.41, 95% CI 0.18-0.85, p=0.023), MI diameter(OR 2.45, 95% CI
1.16-5.34, p=0.021), ALT(OR 0.98, 95% CI 0.97-0.99, p=0.002) and
eGFR(OR 1.01, 95% CI 1.09-1.02, p=0.042) were significantly independent
risk predictors of AF early recurrence. A predictive model was created
with AUC of 0.720. Conclusions: BMI、LAD、MI area、MI diameter、ALT and
eGFR were risk predictors of AF early recurrence. We established a
predictive model and it devote to preoperative clinical health
management of individual with valvular AF.
Integrated pest management for Jatropha Carcus plant: An Impulsive control approach
Authors: Chowdhury Jahangir , Basir Fahad Al , Cao Xianbing , Roy Priti
Published: July 2021

In this research, an integrated pest management model using impulsive
differential equations has been investigated for Jatropha curcas
plantation to control its natural pests through relying on the release
of infective pest individuals and spraying of chemical pesticides. Using
Floquet’s theory and the small amplitude perturbation method, it is
obtained that there exists an asymptotically stable susceptible pest
eradication periodic solution when the release amount of infected pest
is larger than the critical maximum value (or strength of chemical
pesticide spraying is larger than some critical maximum value). Also, we
have established the permanence of the system. After comparison, it is
explored that integrated pest management is more effective than
biological control or chemical control. Finally, verify the analytical
results through numerical simulation.
A new Kunitz-type snake toxin family associated with an original mode of interaction with the vasopressin 2 receptor.
Authors: Droctové Laura , CioleK Justyna , Mendre Christiane , Chorfa Amélia , Huerta Paola , Carvalho Chrystelle , Gouin Charlotte , Lancien Manon , Blanchet Guillaume , Upert Gregory , Pauw Edwin De , Barbe Peggy , Keck Mathilde , Mourier Gilles , Mouillac Bernard , Servent Denis , Rodriguez-de-la-vega Ricardo , Quinton Loïc , Gilles Nicolas
Published: July 2021

Background and purpose. Venomous animals express numerous Kunitz-type
peptides. The mambaquaretin-1 (MQ1) recently identified from the
Dendroaspis angusticeps venom is the most selective antagonist of the
arginine-vasopressin V2 receptor (V2R) and the unique Kunitz-type
peptide active on a GPCR. We aimed to exploit other mamba venoms to
enlarge the V2R-Kunitz peptide family and get insight into the MQ1
molecular mode of action. Experimental approach. We used a bio-guided
screening assay to identify novel MQs and placed them phylogenetically.
Several newly identified MQs were produced by solid phase peptide
synthesis. They were characterized in vitro by binding and functional
tests andin vivo by diuresis measurement in rats. Key results. Eight
additional MQs were identified with nanomolar affinities for the V2R,
all antagonists. MQs form a new subgroup in the Kunitz family, close to
the V2R non-active dendrotoxins and to 2 V2R active cobra toxins.
Sequence comparison between active and non-active V2R Kunitz peptides
highlighted 5 specific V2R positions. Four of them are involved in V2R
activity and belong to the 2 large MQ1 loops. We finally determined that
8 positions, part of these 2 loops, interact with the V2R. The variant
MQ1-K39A showed specificity for the human versus the rat V2R .
Conclusions and implications. A third function and mode of action is now
associated with the Kunitz-peptides. The number of MQ1 residues involved
in V2R binding is large and may explain its absolute selectivity.
MQ1-K39A represents the first step in the improvement of the MQ1 design
for medicinal perspective.
METHODOLOGY OF COST RECORDING AND ACCOUNTING IN DAIRY COOPERATIVES
Authors: Ganc Marzena , Wasilewski Mirosław
Published: July 2021

The purpose of the research is to present the theoretical and practical aspects of determining the unit cost of producing dairy products in what is defined as a "typical" dairy cooperative. The Euclideanand urban distance method was used to determine a typical object with n = 88 dairy cooperatives – the following set of variables was defined, which are common to all cooperatives and reflect the sizeand specificity of cooperative units on the milk market in Poland. The selected cooperative provides a procedure for calculating the unit costs of dairy products on the basis of a detailed case study. Thefull cost account used in cooperatives does not provide cost information for management decisions.Indirect cost accounting using contractual factors does not provide reliable cost data. An important issue in determining the coefficients is the adoption of a measure which reflects the actualrelationship between cost and cost carrier, a product which, in the case of dairy products, may be difficult. It would be appropriate to attempt to introduce a variable cost account in dairy cooperativesin order to avoid the contractual assignment of indirect costs to products. The main problem highlighted by the authors is the lack of an adequate information system for the cost accounting indairy cooperatives. The implementation of such solutions would allow managers of a dairy cooperative to make appropriate (short-term) decisions in terms of developing an assortmentstructure based on data e.g. on profitability at the level of individual products.
On Subclass of Meromorphic Univalent Functions Defined by Multiplier Transformation
Authors: Kazem Mustafa Fawzy , Radhi Ahmed Khalaf
Published: July 2021

In this paper, we will investigate and discuss a new class of meromorphic univalent functions defined by multiplier transformation which is R(c, , y, ), as well as study the coefficient estimates and growth theorems, and then another line in this work, upon to get the close under the convex linear combination
Enhancement of SnO2 for gas sensing applications
Authors: Mahdi O. S. , Mohammed Nadheer Jassim
Published: July 2021

Thin films of SnO2 were deposited by reactive RF magnetron sputtering. It was shown that the films possess gas sensitivity to ethanol vapor at room temperature. XRD, SEM, and EDX measurements of thin films were investigated. Annealing of SnO2 thin films at 800 °С is polycrystalline and grain size of SnO2 in the range about 12 nm. The growth of SnO2 with annealing to 800 °C leads to the percolation nanorods structure. EDX clearly explains the rich of Sn reached 70% annealing. The conductivity of SnO2 nanorods has been increasing at room temperature for ethanol vapors.
Optical and Morphological Properties of Silver Nanoparticles Synthesis by Laser Induced Forward Transfer Technique
Authors: Khdr Noor Fakher , Ahmed Baida M. , Rasheed Bassam G.
Published: July 2021

Various methods could be employed to synthesize nanomaterials. In this work laser induced forward technology was used to synthesize silver nanoparticles. Silver nanomaterials were tested using different measuring instruments such as UV–vis diffuse (DRS), Atomic Force Microscopy (AFM), and optical Microscope to characterize features such as the optical and morphological properties of these nanoparticles. AFM results show that when the laser energy of the pulsed Nd: YAG laser increases, the diameter and roughness of produced AgNPs will be decreased for the same number of pulses and the air cavity between donner and acceptor. Also, results show that when laser energy is (300,400) mJ, the AgNPs diameters are (95.76,88.44) nm and the roughness are (7,6) nm respectively. While, results show that as laser pulses increase, structure to be rougher for different laser pulses and constant laser energy at 300 mJ the same behavior will be found when the laser energy becomes 400mJ.Finally, results show that the reflectance peaks of Ag NPs increase by decreasing the number of pulses to a maximum value of 467 at 2 pulses.
«I touch the future – I teach» – en nomadisk tidsreise om dramaturgi i didaktisk kontekst
Authors: Østern Anna-Lena
Published: July 2021

I denne studien spør forfatteren Hva bidrar en lærerutdanners modelltenkning med, knyttet til dramaturgi i didaktisk kontekst i perioden 1998 til 2021? I studien brukes performance writing innenfor et performativt forskningsparadigme som strukturerende tilnærming. Tre dramaturgiske analysemodeller utviklet som dramaturgididaktisk tenkning, utgjør det empiriske materialet i studien. Modellene bærer spor av den reisen forfatteren har gjort som lærerutdanner, og av de møtene med fenomener og mennesker som har vært og er del av reisen. En preliminær dramaturgisk analysemodell, en relasjonell dramaturgisk analysemodell og en animert nomadisk dramaturgisk analysemodell er konkrete nedslag som bidrar til teoriutvikling. Modellene bærer spor av den utviklingen som har skjedd i løpet av perioden når det gjelder synet på utdannelse, utdanningspolitikk, elevrolle og lærerrolle, fagteori og vitenskapsteori – både internasjonalt og nasjonalt.
Upaya Mitigasi Dampak Covid-19 melalui Kegiatan Pemberdayaan Masyarakat di Desa Banyuasin Kabupaten Bangka
Authors: Bahtera Novyandra Ilham
Published: July 2021

Pandemi Covid-19 telah melanda seluruh dunia pada beberapa bulan terakhir. Hal ini memberikan dampak negatif pada sektor ekonomi dan sosial bagi masyarakat. Walau bagaimanapun, kondisi ini tidak boleh dibiarkan terus berlarut-larut. Perlu ada kegiatan kemasayarakatan agar masalah yang ada dapat diselesaikan. Tujuan kegiatan pengabdian kepada masyarakat di Desa Banyuasin Kabupaten Bangka adalah untuk memberikan kontribusi dan turut berpartisipasi aktif dalam usaha memitigasi dampak dari wabah Covid-19. Kegiatan pemberdayaan masayarakat ini terdiri dari empat bidang yaitu: 1) bidang masyarakat; 2) bidang lingkungan; 3) bidang pendidikan; dan 4) bidang kesehatan. Sosialisasi, pendampingan, kegiatan penyuluhan dan demonstrasi merupakan metode yang dilakukan dengan tetap mengikuti protokol pencegahan Covid-19. Kegiatan ini mendapatkan hasil bahwa masayarakat memberikan umpan balik yang positif dan memiliki kemauan agar kegiatan ini ada keberlanjutannya. Masyarakat mendapatkan manfaat yang dapat dirasakan dari berbagai bidang pada program yang ditawarkan. Kegiatan ini dapat sangat berguna bagi masyarakat Desa Banyuasin menjadi desa wisata berbasis pertanian.
Pemberdayaan Usaha Kerajinan Anyaman Bambu Karya Kelompok Usaha Ibu-Ibu “Sari Murni” Desa Landih, Dusun Buayang-Bangli
Authors: P. Putra I Gst. B Ngr. , Jayawarsa Anak Agung Ketut , Maharani Ida Ayu Dinda Priyanka , Setiyawan Putu Ary
Published: July 2021

The geographical condition, which has a cool climate and abundant supply of bamboo, is used by the people of Landih Village as raw material for producing bamboo-based hand-woven handicrafts, such as sokasi. The business groups that are used as partners in the 2021 community service program come from among women called the “Sari Murni” Socation Craftsman Empowerment Group. The problems faced by partners are: 1) Limited capital, which causes partners to experience difficulties in fulfilling the need for bamboo raw materials and supporting materials 2) Limited skills in recording financial transactions 3) Distribution of products is carried out conventionally. The solutions offered are 1) Provision of Production Support Facilities and Infrastructure 2) Training on Recording of Financial Transactions and Provision of a Digitalized Financial Recording System 3) Provision of Websites as a Form of Marketing Strategy and Online Promotion Strategy Training.
PENDAMPINGAN PENCATATAN KEUANGAN DAN PEMASARAN SARATHI BANTEN DI DESA KAPAL BADUNG
Authors: Mariyatni Ni Putu Sri , Juniariani Ni Made Rai , Pratama Agus Darma Yoga
Published: July 2021

Tukang banten or also known as Sarathi banten is someone who has the obligation and responsibility to prepare offering facilities related to ceremonies performed by Hindus. Mrs. Dewa Ayu Astiti is one of the sellers of offerings as well as Sarathi or artisan offerings, which has been occupied since 2012 located in Ds. Kapal, Kec. Mengwi, Badung. There are several partner problems related to business management, namely not making financial records, not has a promotion system to market its products, and the layout for managing offerings is not yet regular. The types of activities undertaken to assist Sarathi are providing training and assistance in simple financial recording and assistance in product marketing as well as assisting in the procurement of the necessary infrastructure. The purpose of this service activity is to increase the understanding of partners regarding business financial records and marketing, as well as increase the production capacity of their businesses. The result of this activity is an increase in assets, business turnover, total production and an increase in the number of workers.
The Implication of Self-Relevant Value and Value of Travelling Consumption on Propensity to Share Electronic Word of Mouth of Traveler
Authors: Anggarawati Sularsih , Saputra Fachri Eka
Published: July 2021

This study aims to examine the effect of 3 dimensions of self-relevant value (Reflected Appraisal of Self, Conspicuous Value, and Self-Image Congruity) and 3 dimensions of value of traveling consumption (Desire for Experience Travel, Need for Uniqueness, and Social Esteem) on the tendency for someone to share their experiences on social media (e-WOM). To answer the research objectives, this study uses a quantitative research design using cross sectional time dimension of the study. The questionnaire was used as a sample data collection tool, in which the sampling was done purposively. The data collection method used in this study is by distributing online questionnaires by inserting questionnaires into Google Form, then online questionnaires are distributed through social media such as Facebook, Instagram, and WhatsApp. Appropriate respondents to fill out this questionnaire are people who have visited popular tours in Indonesia, especially young tourists. Data analysis method is planned using Multiple Regression Analysis. The results show that four of the six hypotheses are proven in this study. There are two hypotheses that are rejected, specifically the relationship between conspicuous value on propensity to share e-WOM, and the relationship between self-esteem on propensity to share e-WOM. This study gives a contribution to the body of knowledge on the relationship between self-relevant value and desire to experience travel concepts on propensity of travellers to share their experience on the electronic Word of Mouth (e-WOM).
The Influence Of Brand Image And Atmosphere Store On Purchase Decision For Samsung Brand Smartphone With Buying Intervention As Intervening Variables (Study on Samsung Experience Store Karawaci Customers)
Authors: Solihin Dede
Published: July 2021

This study analyses a brand image and store atmosphere on purchasing decisions with purchase intention as an intervening variable at the Samsung Experience Store Karawaci customers. This type of research is a quantitative descriptive study. This research is survey research. The number of samples in this study was 98 people who were determined using the accidental sampling technique. The data in this study were collected using an instrument in the form of a questionnaire. Data were analyzed using path analysis. The results showed that brand image has a significant effect on purchase intention with a path coefficient of (0.152), store atmosphere has a significant effect on purchase intention with a path coefficient of (0.769), purchase intention has a significant effect on purchasing decisions with a path coefficient of (0.305). ), brand image has a significant influence on purchasing decisions with a path coefficient of (0.140), store atmosphere has a significant influence on purchasing decisions with a path coefficient of (0.494), Purchase Interest cannot mediate the influence of the Brand Image variable on Purchasing Decisions This can be seen from a one-tailed probability 0.08417935> 0.05, the Purchase Interest variable can mediate the influence of the Store Atmosphere variable on Purchasing Decisions This can be seen from the one-tailed probability 0.00004590 <0.05
The Concept of Digitalization-based Performance Management In An Effort to Improve Employee Performance During the Covid-19 pandemic in Village-Owned Enterprises (BUMDES) throughout Buleleng Regency
Authors: Adnyana Putu Agus
Published: July 2021

The purpose of this study is to determine employee performance through the concept of work management and digitalization as the main keys to improving the performance of BUMDES employees in Buleleng Regency. The concept of performance management is the employee’s activities and work results in line with organizational goals. So that it contributes to improving the performance of BumDes employees. The study population was all active BumDes in Buleleng Regency. Sampling in this study using random sampling technique. The data analysis technique used in this research is the Component based SEM, Partial Least Square (PLS) analysis method. The results showed that the concept of work management has an effect on digitization and employee performance.
The Effect Of Product Promotion And Innovation On Purchase Decisions At Prices As Intervening Variables
Authors: Sujarwo Joe Eklesia Apostolos , Matruty Eko Suseno Hendro Riyadi
Published: July 2021

The development of digital marketing in the new normal era is currently very fast. Several online shops that use digital marketing techniques such as Shopee and Tokopedia. This study aims to analyzed the effect of promotion and product innovation on purchasing decisions with price as an intervening variable. The research method used purposive sampling technique where the data is examined using measurements by considering individual choices. The sample collection used a questionnaire, and the number of samples used is 100 respondents. The analysis technique used multiple linear regression and multiple test. The results showed that the first hypothesis did not have a significant influence between the promotional variables on purchasing decisions. While the second hypothesis there is a significant influence between product innovation variables on purchasing decisions. Furthermore, the third and fourth hypothesis of the price variable mediate the relationship between promotion and product innovation on purchasing decisions.
La vivienda sustentable para abatir el cambio climático. Caso Tepatitlán de Morelos
Authors: Navarro del Toro Guillermo José
Published: July 2021

Esta investigación se centró en la búsqueda de materiales y tecnologías para la construcción de viviendas de Tepatitlán de Morelos, Jalisco, México, municipio que se está convirtiendo en un polo de desarrollo de viviendas y servicios atractivo para todo tipo y tamaño de empresas. Aprovechando que la Universidad de Guadalajara cuenta con un campus en Tepatitlán, el Centro Universitario de los Altos (CUAltos), se les solicitó a alumnos allí inscritos que llenaran una encuesta que indagaba sobre los materiales con los que se construyeron las casas que habitaban en ese momento. Participaron 80 alumnos de cuatro grupos. Como parte de los resultados se obtuvo que si a las casas habitación se les provee de dispositivos ahorradores de energía, agua y gas se logrará una reducción importante en la huella ecológica, y por lo tanto, se hará una contribución a la sustentabilidad del medio ambiente.
Exploring the students’ adversity quotient in online mathematics learning during the Covid-19 pandemic
Authors: Anggraini Tiara Wahyu , Mahmudi Ali
Published: July 2021

Adversity Quotient (AQ) is a person's ability to overcome difficulties someone faces. It shows how students overcome their difficulties. This study aims to describe the students’ AQ in online mathematics learning during the Covid-19 pandemic era and see if there is an effect of the number of platforms used when learning on students' AQ. A survey method is used with 2093 respondents consisting of Senior High School, Islamic Senior High School, and Vocational High School students from 32 provinces in Indonesia. The instrument of the Adversity Response Profile (ARP) questionnaire consists of 30 statements with two questions each. However, two open-ended questions were given before proceeding to the ARP questionnaire. The ARP questionnaire was made in and distributed through Google Form. The results show that students’ AQ in online mathematics learning was Camper. This means that the respondents were sufficient in overcoming difficulties when learning mathematics online, but they were quickly satisfied with the results which led them not to develop themselves further. Furthermore, there is no effect of the number of platforms used when learning mathematics online on the students' AQ.
Viabilidade econômica e financeira de uma fábrica de argamassas em Mafra/SC
Authors: Sabatke Vinícius , Nunes Rodolfo Vieira , Sales George André Willrich
Published: July 2021

O mercado brasileiro de argamassas industrializadas está estimado em 120 milhões de toneladas, sendo no que o sul brasileiro concentra 15% da demanda nacional de produção de Argamassas. Grandes players fazem parte desse mercado, criando um grande desafio para os empreendedores que têm interesse em concorrer nesse segmento de mercado da construção civil. Entretanto com uma demanda avolumada como essa faz com que questiona-se qual a viabilidade econômica de uma indústria de argamassas em Mafra/SC?. Como metodologia para o desenvolvimento do estudo foi realizada pesquisa de levantamento por meio de dados primários e secundários, com questionários semiestruturados para fornecedores, e obtenção de informações mercadológicas e técnicas na internet, respectivamente. Foram considerados todos os insumos e infraestrutura para a elaboração dos resultados alcançados. Para a viabilidade deste empreendimento, foram avaliados, investimentos iniciais, Valor Presente Líquido (VPL), Taxa Interna de Retorno (TIR), Taxa Mínima de Atratividade (TMA), Índice de Lucratividade (IL) e Payback descontado. A Empresa mostrou-se economicamente viável tendo em um cenário realista o  VPL positivo em R$ 3.507.589,14, TIR de 81,34%, Payback Descontado de 1,6 anos e IL de 4,89.