bluuebunny/crossref_metadata_2025 huggingface dataset:
Optimization and Prediction of Sucker Rod Pump Performance on Well X-1 in Field X in the Future
Authors: Sabaruddin Mohammad Firdaus , Azmi Ilman Muhammad , Firdaus Callula Engrasia Fathoni , Shahrazade Muhamad Reza
Published: March 2020

The performance of the sucker rod pump is influenced by the characteristics of the well and reservoir such as pressure, well productivity, physical properties of the fluid, depth and diameter of the well. Therefore, pumping pumps need to be designed and optimized taking into account these conditions. As time goes on production changes in physical properties occur in the reservoir such as a decrease in reservoir pressure and a decrease in well productivity. Changes in the physical properties of the reservoir will affect the performance of the sucker rod pump. The purpose of this study is to design a sucker rod pump at X-1 well and forecast production in the future. The flow rate determination is obtained from the point of intersection between the pump intake pressure curve and IPR curves both in the present and in the future. In this study the pump speed is set at 10 SPM. Based on this method it was found that the well can produce with a flow rate of 1132 bpd with an oil flow rate of 27 bpd. The stroke length for this condition is 304 inch. Over time the production is estimated to cause the pressure to decrease to 1010 psi in 2040. The decrease in reservoir pressure causes the reduction in the flow rate of sucker rod pump to 1046 bpd with an oil flow rate of 14.6 bopd. So that the magnitude of the reduction in the flow rate of liquid between 2019 and 2040 was 7.6%, while the decrease in the oil flow rate was 45.9%. If the speed is set at 10 SPM, the stroke length needs to be reduced with time. The stroke length was designed to be 304 inches in 3019 and reduced to 281 inches in 2040.
Study of Polymer Flooding Behavior in Heterogeneous Two-Layered Porous Media
Authors: Fathaddin Muhammad Taufiq , Hartono Kartika Fajarwati , Kartoatmodjo Trijana
Published: March 2020

In this paper, a numerical study was conducted to investigate the effect of spatial heterogeneity of multiple porosity fields on oil recovery, residual oil saturation,   polymer retained, and polymer adsorption. The generated porosity fields were applied to UTCHEM for simulating polymer and water flooding in heterogeneous two-layered porous media. From the analysis, the increase of reservoir heterogeneity resulted in higher polymer retention and lower polymer adsorption. In general, polymer flooding results in more balance residual oil saturation in the upper and lower layer than water flooding. This indicated that the vertical sweep efficiency of polymer flooding was better than water flooding. Residual oil saturation ratio between layers after water or polymer flooding was about equal along with the increase of reservoir heterogeneity. Spatial heterogeneity of multiple porosity fields had only a small effect on recovery factor. The variation of the recovery factor of polymer and water flooding due to the reservoir heterogeneity was under 1%.
Bulk Fatigue Induced by Surface Reconstruction in Layered Ni-Rich Oxide Cathodes for Liion Batteries
Authors: Xu Chao , Marker Katharina , Lee Juhan , Mahadevegowda Amoghavarsha , Reeves Philip J. , Day Sarah , Groh Matthias F. , Emge Steffen , Ducati Caterina , Mehdi B. Layla , Tang Chiu C. , Grey Clare P.
Published: March 2020

Ni-rich layered cathode materials are among the most promising candidates for high energy density Li-ion batteries. However, the low cobalt containing materials suffer from rapid degradation, the underlying mechanism of which is still poorly understood. We herein report a novel structure-drive degradation mechanism for the NMC811(LiNi0.8Mn0.1Co0.1O2) cathode, in which a proportion of the material exhibits a lowered accessible state-of-charge (SoC) at the end of charge after repetitive cycling, i.e. becomes fatigued. Ex-situ and operando long- duration high-resolution X-ray diffraction enabled by a laser-thinned coin cell design clearly shows the emergence of the fatigued phase and the increase in its population as the cycling progresses. We show that the fatigue degradation is a structure-driven process rather than originating solely due to kinetic limitations or inter-granular cracking. No bulk phase transformations or increase in Li/Ni antisite mixing were observed by diffraction; no significant change in the local structure or Li-ion mobility of the bulk were observed by 7Li solid-state NMR spectroscopy. Instead, we propose that the fatigue process is a result of the high interfacial lattice strain between the reconstructed surface and the bulk layered structure when the latter is at SoCs above a distinct threshold of ~75 %. This mechanism is expected to be universal to Ni-rich layer cathodes, and our findings provide a fundamental guide for designing effective approaches to mitigate such deleterious processes.
Polinômios: Gráfico, multiplicidade e demonstração.
Authors: Da Silva Junior João Domingos Gomes , Cerveira da Costa Liliana Manuela Gaspar
Published: March 2020

Neste artigo é apresentada uma propriedade de polinômios utilizada para a resolução de um exercício em sala de aula por alunos do 3º ano do Ensino Médio. Apresenta-se também uma demonstração dessa propriedade que seja acessível aos alunos. Algumas definições e teoremas necessários para a demonstração dessa propriedade foram enunciados e alguns exemplos de aplicação foram apresentados. Procurou-se elucidar de forma clara nossa proposta pedagógica para que outros colegas a possam utilizar com seus respectivos alunos. Junto com a propriedade, inevitavelmente, é retomada a discussão sobre a utilização ou não de demonstrações matemáticas com os alunos dos Ensinos Fundamental e Médio.
Discussões entre professora e alunos em um ambiente de modelagem geométrica
Authors: Sant'Ana Alvino Alves , Sant'Ana Marilaine de Fraga , Serpa Paula Beatriz da Silva
Published: March 2020

Neste trabalho, tecemos reflexões a partir de uma experiência de modelagem geométrica de logotipos de marcas, classificada como intermediária entre o segundo e o terceiro casos, ao considerar-se a relação entre Modelagem Matemática e currículo segundo Barbosa (2001), que se desenvolve dentro da perspectiva educacional de acordo com Kaiser e Sriraman (2006). Observamos a dinâmica em uma sala de aula do Ensino Médio com foco nas atuações da professora e dos estudantes durante as discussões realizados neste ambiente de aprendizagem. Registramos evidências de que: as discussões foram matemática ou técnicas, com prioridades para a primeira categoria. A atuação da professora, em consonância com a Pedagogia da Pergunta, favoreceu a autonomia do grupo, que desenvolveu a tarefa com algum grau de independência, conectando conhecimentos prévios e novas experiências e, apesar de algumas dificuldades, saiu da zona de conforto de atividades fechadas e bem determinadas.
Reconfiguração curricular em química por meio de uma situação de estudo: a negociação coletiva de saberes
Authors: Lauxen Ademar Antonio , Segalin Camila , Zoch Alana Neto , Vaniel Ana Paula Härter , Ortiz Janaína Chaves , Tres Lairton
Published: March 2020

O presente artigo tem como objetivo apresentar os resultados da construção coletiva desenvolvida num projeto de extensão. O projeto é realizado no curso de Química licenciatura, da Universidade NOME. Neste texto, apresentam-se os resultados decorrentes da elaboração e da aplicação de uma Situação de Estudo (SE) em seis escolas de educação básica, com participação de 176 estudantes do primeiro ano do ensino médio. O tema proposto para a SE foi combustão, especialmente por sua ligação com a vivência dos estudantes. Essa SE possibilitou maior contextualização e aperfeiçoamento do processo de ensino e aprendizagem, bem como contribuiu para a formação continuada dos professores por meio da reflexão acerca da própria prática pedagógica, contribuindo, também para a formação inicial dos acadêmicos-bolsistas, integrantes do projeto e professores-formadores que puderam conhecer e refletir sobre a realidade da sala de aula e da escola.
Padrões e o trabalho com sequências recursivas: uma abordagem no desenvolvimento do pensamento algébrico
Authors: Theodorovski Ronaldo , Oliveira Fabiane
Published: March 2020

Este trabalho tem por objetivo apresentar propostas pedagógicas para o ensino da álgebra tendo em vista promover o desenvolvimento do pensamento algébrico dos alunos. Para tanto foi realizado um levantamento bibliográfico buscando trabalhos que demonstram que tal objetivo pode ser alcançado por meio de um ensino que prioriza o reconhecimento e a generalização de padrões matemáticos. Para contemplar o Ensino Médio, demos destaque às sequências definidas recursivamente, que se revelam como um bom ponto de partida para a generalização de padrões. Além disso, com o estudo de recorrências matemática, é possível propor uma abordagem alternativa para o ensino de progressões. Buscando trabalhar com regularidades numéricas para descrever e generalizar relações, sugerimos a utilização das questões da Olimpíada Brasileira de Matemática das Escolas Públicas (OBMEP), como proposta metodológica no ensino da álgebra.
Intervenção educativa sobre febre amarela com alunos de uma Escola Pública Federal em Floriano, Piauí, Brasil
Authors: Freitas Wanderson Lopes dos Santos , Pacheco Raíla Kely de Sousa , Santos Araújo Maurício , Leite Aracelli de Sousa
Published: March 2020

A Febre Amarela é uma doença infecciosa não contagiosa, transmitida ao homem pela picada de mosquitos hematófagos da família Culicidae. Contabiliza-se no mundo cerca de 200 mil casos por ano, e causando a morte de 30 mil pessoas principalmente em áreas de clima tropical. Sendo assim, este trabalho buscou compreender o nível de conhecimento dos alunos da 2ª série do Ensino Médio de uma Escola Federal de Floriano, Piauí, sobre a Febre Amarela, visando orientá-los sobre a temática, por meio de uma intervenção educativa com a utilização de uma revista informativa como material didático alternativo. Adotou-se uma pesquisa com abordagem quali-quantitativa. Aplicou-se um questionário pré-teste com perguntas fechadas antes da intervenção, e um pós-teste depois da aula. Verificou-se que os alunos não possuíam um conhecimento satisfatório sobre a doença, principalmente sobre o agente etiológico, vetor e espécies responsáveis pela transmissão da Febre Amarela no ciclo urbano e silvestre. A doença não é frequentemente abordada em sala de aula. Portanto, após a intervenção educativa com auxílio da revista foi possível verificar a construção de uma aprendizagem siginificativa sobre os pontos-chave da doença e sua profilaxia. Assim, essas metodologias alternativas no âmbito escolar podem promover a construção do conhecimento e consequentemente a promoção da saúde.
ÇATIŞMA YÖNETİMİ Mİ YOKSA ÇATIŞMA ÇÖZÜMÜ MÜ?: BARIŞ MÜZAKERE SÜRECİNE TEORİK OLARAK YAKLAŞMAK
Authors: KÖKSOY Fulya
Published: March 2020

Günlük hayatın doğal bir parçası olan ve tarafların

uyumlaştırılamayan çıkarları nedeniyle yaşadıkları mücadele olarak tanımlanan

çatışmaların, özellikle Soğuk Savaş sonrası dönemde artış gösteren iç silahlı

çatışmalara dönüştüğü görülmektedir. İçinde bulunduğumuz yüzyılda da Dünya’nın

farklı coğrafyalarında yaşanan iç silahlı çatışmalar ise çatışma ve barış

araştırmaları evrelerinin tümünü kapsayan çatışma yönetiminin bir alt evresi

olan çatışma çözümüne ve çatışma çözümünün aşamalarından biri olan barış müzakere

süreçlerine alan açmaktadır.

Bu

çalışmanın temel odak noktasına çatışma yönetimi ve çatışma çözümü kavramları

konularak barış müzakere süreçlerine teorik olarak yaklaşılmaktadır. Bu yönde

bir çalışma oluşturulmasının temel amacı ise hassas bir aşamayı temsil eden

barış müzakere süreçlerinin kavramsal ve teorik çerçevesini oluşturmaktır. Öte

yandan, iç silahlı çatışmalar özelinde çatışmayı sona erdirme amacıyla

tarafların etkileşimini ifade eden barış müzakere süreçlerinin, barış

araştırmaları literatürü çerçevesinde hangi üst başlık altında

kavramsallaştırıldığı analiz edilmektedir. Bu bağlamda çatışma analizi ve barış

araştırmaları literatüründe çatışma çözümü ve yönetimi kavramlarının bir üst

başlık olarak mı kullanılması gerektiği yoksa barış süreci ekseninde ayrı bir

süreci mi ifade ettiği hususu ele alınmaktadır.
REALİZM VE NEOREALİZM BAĞLAMINDA SOĞUK SAVAŞ SONRASI GÜVENLİK ANLAYIŞININ DEĞERLENDİRİLMESİ
Authors: ÖZDOĞAN Mücahit
Published: March 2020

Soğuk Savaş sonrası güvenlik alanı, birey güvenliğinin öne çıkması, ulus devletin zayıflaması ve askerî güvenliğin görece öneminin azalması itibarıyla köklü değişimlere uğramış olsa da bugün dünya çapında konuşulan konulara bakıldığında Realizm ve Neorealizmin öne sürdüğü fikirsel çerçevenin hâlâ devam ettiği çeşitli verilerle birlikte görülmektedir. Bu makale Realizm ve Neorealizm çerçevesinde mevcut güvenlik ortamını analiz etmeyi amaçlamaktadır. Terör ve sınır sorunları gibi problemlerden dolayı askerî seçeneklerin hâlâ güçlü bir koz olması, uluslararası ilişkiler teorileri bakımından değerlendirilecektir. Mevcut uluslararası ilişkiler ve uluslararası güvenlik ortamı analiz edilerek devletlerin hâlâ güçlü bir konumda yer aldıklarına dikkat çekilmiştir. Özellikle son yıllarda iç savaşların uluslararası gündemde daha fazla yer edinmesi ve insanları etkilemeye başlamasıyla birlikte askerî seçenekler ön plana çıkmaya başlamış, istikrarsız bölgelerde güçlü devletler çıkar yarışına girmişlerdir. Karşılıklı bağımlılığın gittikçe artmasının yanı sıra yeni ittifak yapılarının ve blokların oluştuğu, Suriye İç Savaşı gibi güncel konular izlendiğinde görülmektedir. İç savaşlar ve istikrarsızlıklar Realizm ve Neorealizmin tezlerini doğrulayabilecek özellikler taşımaktadır.
Assessing Protein-Drug Resistance Due to Mutations via a Rigidity Analysis in silico Approach
Authors: Carpenter Dylan , Thackray Tess , Kalthoff Cecilia , Jagodzinski Filip
Published: March 2020

A mutation to the amino acid sequence of a protein can cause a biomolecule to be resistant to the intended effects of a drug. Assessing the changes of a drug’s efficacy in response to mutations via mutagenesis wet-lab experiments is prohibitively time consuming for even a single point mutation, let alone for all possible mutations. Existing approaches for inferring mutation-induced drug resistance are available, but all of them reason about mutations of residues at or very near the protein-drug interface. However, there are examples of mutations far away from the region where the ligand binds, but which nonetheless render a protein resistant to the effects of the drug. We present a proof-of-concept computational pipeline that generates in silico the set of all possible single point mutations in a protein-ligand complex. We assess drug resistance using a graph theoretic rigidity analysis approach. Unlike existing methods, we are able to assess the impact of mutations far away from the protein-drug interface. We introduce several visualizations for exploring how amino acid substitutions both near and far away from where the ligand interacts with a protein target have a stabilizing or destabilizing effect on the protein-drug complex. We discuss our analytical approach in the context of experimental data from the literature about clinically known protein-drug interactions.
Mining approximate frequent dense modules from multiple gene expression datasets
Authors: Seo San Ha , Salem Saeed
Published: March 2020

Large amount of gene expression data has been collected for various environmental and biological conditions. Extracting co-expression networks that are recurrent in multiple co-expression networks has been shown promising in functional gene annotation and biomarkers discovery. Frequent subgraph mining reports a large number of subnetworks. In this work, we propose to mine approximate dense frequent subgraphs. Our proposed approach reports representative frequent subgraphs that are also dense. Our experiments on real gene coexpression networks show that frequent subgraphs are biologically interesting as evidenced by the large percentage of biologically enriched frequent dense subgraphs.
Exposure Measurements on Biomimetic Lobules Using Virtual Experiments to Help Improve IVIVE
Authors: Krishnan Preethi , Dutta Lopamudra , Smith Andrew , Ropella Glen , Kennedy Ryan , Hunt Anthony
Published: March 2020

The in vitro-in vivo extrapolation (IVIVE) methods used currently to predict the hepatic clearance of new chemical entities are plagued by poorly understood inaccuracies. To begin identifying plausible sources, we challenge two of core hypotheses. Hypothesis-1: the intralobular micro-anatomical organization of hepatocytes (HPCs) can be abstracted away. By accepting that hypothesis, one can assume that intrinsic clearance per HPC is essentially the same in vitro and in vivo, and thus an IVIVE method can employ a simplified liver model, typically the “well-stirred” liver model. Hypothesis-2: when the simplified liver model is the “parallel tube model,” drug concentration decreases exponentially from portal to central vein. When either simplified liver model is used, a core assumption is that intrinsic clearance is directly proportional to the unbound fraction of drug. A barrier to progress has been the fact that it is currently infeasible to challenge the two hypotheses using wet-lab experiments. In this work, we challenge virtual counterparts of the two hypotheses by experimenting on virtual mice in which hepatic disposition and clearance are consequences of concretized model mechanisms that have met several demanding requirements, including the following. The virtual liver’s structure and organization are strongly analogous to those of an actual liver, and the hepatic disposition and clearance of several virtual compounds have achieved quantitative validation targets. We study two virtual compounds. Compound-1 simulates the extreme of low-clearance, highly permeable compounds. Compound-2 simulates a highly permeable compound exhibiting maximum intrinsic clearance. We simulate changes in unbound fraction by changing the probability (pEnter) that a Compound-1 or -2 will enter an adjacent HPC during a simulation cycle. Compound-1 and -2 HPC exposure rates do not decrease from portal to central vein: they increase, and that contradicts both hypotheses. Further, the relationship between exposure rates and pEnter is nonlinear. The insights achieved help explain the frequently reported underprediction of in vivo hepatic clearance values. We suggest that IVIVE methods can be improved by utilizing a liver model that couples a biomimetic representation of intralobular HPC organization with biomimetic representations of intrahepatic disposition dynamics.
SAT, Computer Algebra, Multipliers
Authors: Kaufmann Daniela , Biere Armin , Kauers Manuel
Published: March 2020

Verifying multiplier circuits is an important problem which in practice still requires substantial manual effort. The currently most effective approach uses polynomial reasoning. However parts of a multiplier, i.e., complex final stage adders are hard to verify using computer algebra. In our approach we combine SAT and computer algebra to substantially improve automated verification of integer multipliers. In this paper we focus on the implementation details of our new dedicated reduction engine, which not only allows fully automated adder substitution, but also employs polynomial re- duction efficiently. Our tool is furthermore able to generate proof certificates in the practical algebraic calculus and we also investigate the size of these proofs for one specific multiplier architecture.
Classification of functional Near Infra Red Signals with Machine Learning for Prediction of Epilepsy
Authors: Rosas Romero Roberto , Guevara Edgar
Published: March 2020

This work presents the classification of functional near-infrared spectroscopy (fNIRS) signals as a tool for prediction of epileptic seizures. The implementation of epilepsy prediction is accomplished by using two classifiers, namely a Support Vector Machine (SVM) for EEG-based prediction and a Convolutional Neural Network (CNN) for fNIRS-based prediction. Performance was measured by computing the Positive Predictive Value (PPV) and the Accuracy of a classifier within a 5-minute window adjacent and previous to the start of the seizure. The objectives of this research are to show that fNIRS-based epileptic seizure prediction yields results that are superior to those based on EEG and to show how deep learning is applied to the solution of this problem.
Predicting Microvascular Invasion of Hepatocellular Carcinoma by texture analysis of multi-phase MR image
Authors: Yu Qin , Chen Geng , Li Jiaqi , Liu Xiaolong , Zhang Xuegong , Lu Haiming
Published: March 2020

Microvascular invasion (MVI) diagnosis is of vital importance in the curative treatment of hepatocellular carcinoma patients due to its close relationship with prognostic analysis. Currently, MVI detection often bases on surgical specimen, which is invasive for patients. This study, we extracted texture features of multi-phase MR image to predict the presence of MVI. Feature extraction employed neighboring gray level dependency emphasis (NGLDM) method, which is a common texture feature analysis method. Next, we built a SVM classifier to predict the presence of MVI using extracted features. Especially, multi-phase features were designed to enhance the precision of prediction. Enhanced MR images of pre-contrast phase and portal vein phase were used to extracting features. The method was tested by 5-fold cross- validation on the dataset. The precision of prediction was 91.31%, compared with the baseline method of 70.71%. To make the prediction more interpretable, the relationship between NGLDM texture features and the presence of MVI was discussed in the end.
Towards Word Sense Disambiguation by Reasoning
Authors: Álvez Javier , Gonzalez-Dios Itziar , Rigau German
Published: March 2020

In this paper, we describe a practical application of Vampire for Word Sense Disam- biguation (WSD), which is an important research area in the field of Natural Language Processing (NLP). Its objective is choosing the intended sense of a word in a given context. In particular, we propose a method for the automatic disambiguation of the semantic rela- tions in BLESS, which is a dataset designed to evaluate models of distributional semantics, by choosing the WordNet synset it belongs to. For this purpose, we use the knowledge in Adimen-SUMO, which is obtained by means of a suitable transformation of the knowledge in the core of SUMO1 into first-order logic (FOL) and enables its use by FOL automated theorem provers such as Vampire. By exploiting the semantic mapping between WordNet and SUMO, we apply a black-box testing method that enables the automatic creation a set of conjectures for each word pair by considering the semantic relations provided by BLESS. Then, these conjectures are evaluated using Vampire and, according to the outcomes, each word is disambiguated to a single synset. Finally, we compare the results provided by our proposal and different disambiguation systems that can be found in the literature.
Identification of Deregulated Transcription Factors Involved in Specific Bladder Cancer Subtypes
Authors: Champion Magali , Chiquet Julien , Neuvial Pierre , Elati Mohamed , Radvanyi François , Birmelé Etienne
Published: March 2020

Comparison between tumoral and healthy cells may reveal abnormal regulation behaviors between a transcription factor and the genes it regulates, without exhibiting differential expression of the former genes. We propose a methodology for the identification of transcription factors involved in the deregulation of genes in tumoral cells. This strategy is based on the inference of a reference gene regulatory network that connects transcription factors to their downstream targets using gene expression data. Gene expression levels in tumor samples are then carefully compared to this reference network to detect deregulated target genes. A linear model is finally used to measure the ability of each transcription factor to explain these deregulations. We assess the performance of our method by numerical experiments on a public bladder cancer data set derived from the Cancer Genome Atlas project. We identify genes known for their implication in the development of specific bladder cancer subtypes as well as new potential biomarkers.
Software libre: Incidencia en el proceso de enseñanza-aprendizaje de la educación básica
Authors: Rodríguez Juan Carlos Romero , Acurio Acurio Mónica Patricia , Alvarado Pazmiño Evelin Roxana
Published: March 2020

El presente trabajo de investigación pretende, hacer un diagnóstico acerca de cuáles son las estrategias metodológicas más utilizadas en el proceso de enseñanza-aprendizaje, las metodologías empleadas por los docentes y la manera cómo los alumnos procesan la información. Además de establecer si el tipo de evaluación realizada por el docente de Informática, participante en esta investigación, conduce a los alumnos al desarrollo lógico, de habilidades, y destrezas, en especial el uso de estrategia metodológica para la enseñanza-aprendizaje del software libre en la educación básica. En los antecedentes de la investigación, se describe el problema que tienen los estudiantes del Décimo año de Educación General Básica, en la Unidad Educativa “Emigdio Esparza Moreno”, en cuanto al proceso enseñanza-aprendizaje del software libre, constituyéndose esto en una base indispensable en la investigación y desarrollo. Con la aplicación de las técnicas de investigación estudiadas, se podrán dar las estadísticas reales, de la actual situación del sistema de enseñanza-aprendizaje.En las encuestas que se realizaron en la unidad educativa, especialmente a los estudiantes, docentes, rector; se puede apreciar en forma generalizada que a todas las personas encuestadas, el 80% no están de acuerdo con la enseñanza-aprendizaje del software libre en la educación básica, ni con la actitud de los docentes. En la propuesta se hace referencia del uso de estrategias metodológicas adecuadas que permiten un aprendizaje efectivo del software libre; cumpliendo coherentemente con las sugerencias que deberán tomarse para el proceso de enseñanza-aprendizaje.
Gobernanza democrática, descentralización y territorio: Análisis del plan Chiloé en Chile
Authors: Montecinos Egon , Neira Víctor , Díaz Guillermo , Park James
Published: March 2020

Este artículo analiza el desarrollo del plan Chiloé entre 2007 y 2009, a fin de identificar la existencia de elementos constitutivos de gobernanza territorial en contextos altamente centralizados como el caso chileno. La hipótesis que se sostiene es que las agendas territoriales en casos de centralismo político se activan y visibilizan a raíz de conflictos pero no logran transformarse en procesos permanentes de gobernanza y gestión territorial. Las respuestas del Estado se entregan bajo la misma lógica de funcionamiento del gobierno centralizado, no modifican su diseño institucional y terminan transformándose más en estrategias para legitimar al gobierno de turno, que para avanzar en descentralización o empoderar territorios locales con enfoque territorial. La metodología utilizada fue entrevista a actores clave y revisión de fuentes documentales.
Pergerakan Riset Dalam Pengembangan Teknologi Nano Di Indonesia
Authors: Putra Nurjaman Gunadi , Yuliar Sonny
Published: March 2020

Perkembangan riset terkait teknologi nano di negara-negara maju mempengaruhi riset teknologi nano di Indonesia. Oleh karena itu, penelitian ini dilakukan untuk mengetahui bagaimana pergerakan riset nano di Indonesia khususnya di lembaga penelitian dan pengembangan (litbang) dan perguruan tinggi serta melihat perkembangan kebijakan pemerintah Indonesia terkait dengan riset teknologi nano. Metodologi penelitian yang digunakan adalah kualitatif eksploratif dengan pendekatan teori jaringan-aktor (actor-network theory) untuk melihat relasi pada aktivitas riset teknologi nano di Institut Teknologi Bandung (ITB), Universitas Indonesia (UI) dan Nano Center Indonesia (NCI). Hasil penelitian ini menunjukkan bahwa terdapat pergerakan yang berbeda di Institut Teknologi Bandung dan Universitas Indonesia, dimana Institut Teknologi Bandung memilih pendekatan membuat satu pusat riset terkait ilmu nano dan teknologi nano, sedangkan Universitas Indonesia memilih pendekatan membuat beberapa pusat riset yang tersebar di beberapa fakultas. Lain halnya dengan pergerakan riset teknologi nano di Nano Center Indonesia yang fokus utamanya adalah menghasilkan produk.

Kata kunci : Teknologi nano, Kebijakan, Riset di perguruan tinggi, Riset di lembaga litbang
The Synthesis of PbZr0.52Ti0.48O3 and PbZr0.58Ti0.42O3 Ceramic Powder by Use Molten Salt Method and Its Intermediate Product Analysis
Authors: Ahda Syahfandi , Mardiyanto Mardiyanto , Taufiq Agus , Silalahi Marzuki
Published: March 2020

Lead zirconat titanate, Pb(Zr1-x,Tix)O3 is a material with high piezoelectric properties and many studies have been carried out in development, in order to improve the materials quality in various applications. Therefore,one of them is the development of synthesis with the molten salt method in this study. Choice of the molten salt method is simply and and not expensive. The salt ratio of NaCl / KCl at 1: 1 in moles as a solvent medium was carried out in synthesizing Pb(Zr1-x,Tix)O3. Likewise, the salt ratio with reactant/basic material was 1: 1 in weight percentages. An intermediate product is obtained if the dynamics of chemical reactions in the diffusion process occur indirectly or in stages. To identify intermediate products in this synthesis process, the sintering temperature has been varied to 575, 675 and 775 oC for samples A, B and C, respectively. The results of these syntheses have been identified and characterized using x-ray diffraction (XRD) methods. The Highscore program using the Rietveld method to identify the intermediate product content and each crystal structure has been applied in the rifenement process on the XRD intensity profile with a statistical error of less than 6%. Intermediate products have been obtained as follows, PbTiO3, PbZrO3 and Zr0.4Ti0.6O3. Whereas sample C has obtained two phases namely PbZr0.52Ti0.48O3 and PbZr0.58Ti0.42O3 with tetragonal (P4mm) and rhombohedral crystal structures (R3c).
An Effect Of Biodiesel (B20) On Life Time Locomotive Fuel Filter
Authors: Maruf Muhammad , Haryono Ihwan
Published: March 2020

The effect of using B20 palm oil biodiesel on rail locomotive fuel filters was evaluated in this study. The generator water separator filter, generator main filter and locomotive drive filter after being used along the filter replacement period were analyzed in laboratories and compared with new ones as reference. The analysis was using SEM/EDS, FTIR and GC. The FTIR and GC test results show that the fuel filter has a number of deposits from the components of biodiesel fuel, that are diesel and biodiesel. However, morphological test results using SEM show that the filter surface has not been completely covered by liquid and fuel deposits. The results of the tests and analysis indicated that the usage of 125 hours (for locomotive genset) and 3 months for locomotive drive engine with 20% palm biodiesel fuel can still guarantee the filtration to maintain the performance and prevent damage to fuel and engine system components.
Partisipasi Perempuan Tani Dalam Usaha Tani Stroberi di Desa Santong Kabupaten Lombok Utara
Authors: Syarif Iqbal Syarif
Published: March 2020

Penelitian ini bertujuan untuk: 1) Untuk mengetahui partisipasi perempuan tani dalam usahtani stroberi di Desa Santong Kabupaten Lombok Utara, 2) Untuk mengetahui Faktor-Faktor yang Memiliki Hubungan dengan Tingkat Partisipasi dalam Usahatani Stroberi di Desa Santong Kabupaten Lombok Utara. Hasil penelitian menunjukan bahwa tingkat partisipasi perempuan tani dalam usahatani stroberi di Desa Santong Kabupaten Lombok Utara termasik dalam kategori sedang dengan 27 dari 49 responden mendapatkan nilai interval skor 20-28. Dalam partisipasi ini terdiri dari tahap perencanaan dan tahap pelaksanaan dimana tahap perencanaan terdiri dari 4 kegiatatan yaitu menentukan jenis tanaman yang akan ditanam, pemanfaatan modal, menentukan jumlah tanaman yang ditanam dan pembagian kerja sedangkan pada tahap pelaksanaan ada 8 kegiatan diantaranya pembuatan media tanam, pembibitan, penanaman, penyiraman, penyulaman, pemupukan,pemangkasan, panen. Rendahnya partisipasi perempuan tani dalam tahap perencanaan disebabkan budaya masyarakat daerah santong yang masih mengharuskan perempuan harus lebih banyak berada di rumah untuk mengurus pekerjaan seperti memasak, bersih,bersih dan mengurus anak sedangkan pada tahap perencanaan pada pembinaan yang dilakukan dengan cara pendekatan kelompok tani dimana dominan dihdiri oleh laki-laki sehingga laki-laki lebih dominan dalam tahap perencanaan dan kegiatan pelaksanaan yang mudah dilakukan seperti penyiraman dan panen dilakukan dominan oleh perempuan yang lebih sering dirumah menguerus tanaman di lahan pekarangan. Menurut hasil uji spearman tidak terdapat faktor-faktor yang memiliki hubungan dengan partisipasi perempuan tani dalam usahatani stroberi di Desa Santong karena semua faktor memiliki nilai signifikan lebih dari 0,05.
De que se ocupa a Cristologia?: Pressupostos e relevância
Authors: Tavares Sinivaldo
Published: March 2020

Este estudo enfatiza a peculiaridade da Cristologia, concebida como reflexão feita em estreita relação com a concreta experiência de fé eclesial. É do húmus da fé que a Cristologia extrai a seiva necessária à sua sobrevivência. São muitos os desafios que emergem no seio das comunidades cristãs atuais, no tocante à fé em Jesus Cristo. O Autor prioriza dois fenômenos que estão na origem dos principais desafios: o "retorno do sagrado aliado à expansão vertiginosa do "movimento pentecostal ", e o "diálogo inter-religioso ". Com o intuito de robustecer a fé eclesial, propõe um confronto entre fé eclesial e Cristologia. Torna-se imprescindível, em tal caso, resgatar as atitudes e a mensagem do Jesus histórico — com base sobretudo no testemunho oferecido pelos evangelhos — como critério de verificação da autenticidade da fé em Jesus Cristo.Abstract: This study puts emphasis on the singularity of Christology, seen as a reflection in strict relationship with the concrete experience of eclesial faith. It is from the humus of faith that Christology extracts the sap necessary to its survival. The challenges are many which emerge in the heart of present-day Christian communities, in that which touches upon faith in Jesus Christ. The author singles out two phenomena which are at lhe base of the main challenges: the "return to the sacred", allied to the extraordinary expansion of the "charismatic movement", and the "inter-religious dialogue". With the finality of strangthening eclesial faith, a confrontation is proposed between ecclesial faith and Christology. It becomes unavoidable, in such a case, to rescue the attitudes and lhe message of the historical Jesus — above all based upon the testimony given within the Gospels — as criteria of verification of the authenticity of faith in Jesus Christ.
Dom Helder: um sopro progressista na Arquidiocese de Olinda e Recife
Authors: Silva Severino Vicente da
Published: March 2020

O trabalho se popõe a discutir e questionar afirmações que defendem ter a Arquidiocese de Olinda e Recife, os cristãos católicos, optado por uma linha progressista de atuação a partir dos anos sessenta. Queremos argumentar que o período de pastoreio de Dom Helder Câmara (1964-1985) à frente da Arquidiocese foi um interregno progressista, ocorrido em uma sociedade de caráter conservador e que não chegou a alcançar os fundamentos da prática dos católicos da Arquidiocese.Abstract: This study proposes to discuss and challenge some of the statements defending the hypothesis that the Archdiocese of Olinda and Recife – the Catholic Christians – opted for a progressive line of action from the 60s onwards. We wish to argue that the pastorship of Dom Helder Câmara (1964-1985) at the head of the Archdiocese was a progressive interregnum that occured in a society ofa conservative nature and did not succeed in reaching the foundations of the practice of the Archdiocese's Catholics.
Medición del valor económico agregado EVA de las empresas de Caldas en el periodo 2000-2008
Authors: Escobar Arias Gabriel Eduardo , Arango Álvarez Rubén Dario , Molina Osorio Alejandra , Arias Vargas Francisco Javier
Published: March 2020

Esta investigación está basada en el reporte de información de los estados financieros consignados de forma continúa por las empresas de Caldas durante el periodo 2000-2008 ante la Superintendencia de Sociedades que permitió calcular y obtener la variación de dicho índice.Para lograr este cometido, primero, se depuraron los estados financieros, luego, se extrajeron las cuentas contables necesarias para el cálculo de la rentabilidad operativa y el costo del capital promedio ponderado, y así obtener el Valor Económico Agregado en términos porcentuales.Por último, se presenta un análisis del comportamiento del EVA del sector industrial, comercial, agroindustrial y de actividades, debido a que son los más representativos en cuanto a agrupación de número de unidades de negocio.
Aportes del posestructuralismo y el posmodernismo al desarrollo del pensamiento contable La perspectiva de Norman Macintosh
Authors: Franco Ruiz Rafael
Published: March 2020

Este documento constituye una revisión de literatura contable desde perspectivas posestructuralistas y posmodernistas, a partir de la producción intelectual de Norman Macintosh. Se basó en la hermenéutica como recurso metodológico para desentrañar la realidad profunda de los planteamientos de Macintosh, sus fuentes filosóficas y los criterios de pensadores de su tiempo. La actividad interpretativa de Macintosh parte de la teoría literaria, avanza al estructuralismo y, luego, al posestructuralismo donde aborda la aplicación de la deconstrucción. El último escenario posestructuralista es la contabilidad heteroglósica, considerando que un texto tiene diferentes lecturas, que permiten diferentes interpretaciones para diversos usos.El siguiente nivel de análisis lo constituye el giro posmoderno, presentando interpretaciones de la contabilidad como dispositivo de poder, que permite controlar, a partir de la idea de pan� -ó� ptico, según la cual, se pueden vigilar las acciones de una población en un determinado espacio, sin ser observado, desarrollando una comunidad disciplinaria. Finalmente, Macintosh afirma que los informes perdieron sus referentes reales constituyendo un sistema de signos autorreferentes, presentándose la confusión de sujeto y objeto, sustanciando los conceptos. A partir de esto, se desarrollan argumentaciones sobre la verdad, que no es un valor absoluto, es diversa, un asunto de perspectiva, parcial e interesado.La obra de Macintosh explica problemas de teoría e información contable, pero deja dos asuntos en deuda. No devela los procesos de medición y valoración, los considera una acción unificada, dejando velos sobre la comprensión de problemas relacionados con la verdad, la riqueza y la propiedad; sus análisis de la contabilidad como dispositivo de poder sólo consideran la acción de vigilar y castigar en una dirección, del poderoso al subordinado, ignorando su potencia política que permite el control ciudadano sobre las empresas.
Un aporte de Richard Laughlin a la contabilidad: El pensamiento de Middle-Range
Authors: Jiménez Aguirre Rubiela
Published: March 2020

Presentar la metodología de Middle-Range, como uno de los aportes de Richard Lauglin a la contabilidad, se convierte en un reto para los investigadores en el sentido de la comprensión de esta metodología como una forma de investigación empírica en la corriente crítica de la contabilidad; es una forma de interrelacionar la teoría, la metodología y la postura del investigador; es decir, la elección de mantener el Statu-quo o del cambio depende de su actitud y de su comprensión.
Ventajas y oportunidades no aprovechadas para la formación integral de contadores públicos desde la perspectiva de Conocimiento e Interés
Authors: Rueda Delgado Gabriel
Published: March 2020

El proceso de convergencia contable que el país viene asumiendo desde la Ley 1314 de 2009, puede representar una posibilidad de ajuste sustantivo en el proceso de formación del profesional contable en Colombia, no sólo por su alto impacto en la transformación de las normas técnicas que el futuro profesio-nal debe manejar, sino, por la posibili-dad de acercarse a la comprensión de fenómenos que como la internacionali-zación, la globalización etc., requieren de ser problematizados. Igualmente, representan la posibilidad de aumentar las miradas críticas que tanto se le recla-man al profesional contable colombiano pero que poco se ven materializadas en su proceso de formación y estructura curricular.
Las dificultades de pensar por sí mismo en las facultades de economía
Authors: Ariza Ruiz Efrén Danilo
Published: March 2020

El presente artículo, busca enunciar una serie de problemas epistemológicos del paradigma dominante de la economía y cuestionables prácticas cotidianas en el aula, que dificultan la consolidación de un pensamiento propio en los estu-diantes. La pretensión de la economía de convertirse en la más dura de las ciencias sociales, la absolutización del método matemático, la crisis de perti-nencia, realismo y coherencia, el abuso del recurso al ceteris paribus, el uso excesivo de manuales y las tendencias mundiales de homogenización dificultan, en la práctica, en nuestras actividades cotidianas en el aula contribuir a ese proceso de construcción de alternativas de solución a los problemas concretos que enfrenta la economía, en este sen-tido, lo que se busca aquí es dinamizar el proceso de debate al interior de las facultades de economía con miras a consolidar epistemológicamente ese proceso.
Создание стабильной высокопродуктивной платформы на основе клеток CHO, адаптированных к химическому и механическому стрессам
Authors: Воронина Е. , Недилько П. , Лобанова Н. , Трусова И. , Холодова А. , Марыгин Р. , Серегин Ю.
Published: March 2020

Возрастающий спрос на получение рекомбинантных молекул требует создания не только стабильных, но и высокопроизводительных клеточных линий, пригодных для масштабного производства. В настоящей работе предложен дизайн вектора для эффективной и стабильной экспрессии рекомбинатных моноклональных антител в клетках CHO и схема адаптации линии CHO-S (реципиента) к высокой осмоляльности среды в условиях повышенного содержания хлорида натрия (до 100 мМ), лактата натрия (до 170 мМ) и скорости перемешивания в биореакторе до 240 об/мин. Показана эффективность полученной клеточной платформы на примере экспрессии моноклонального антитела IgG2/4k, позволяющей получать до 2,5 г/л продукта без амплификации гена интереса и оптимизации условий культивирования в режиме fed-batch.
Новое лекарственное средство «Пентафитон» и его адаптогенная активность
Authors: Корнопольцева Т. , Петунова А. , Ботоева Е. , Петров Е.
Published: March 2020

На основе тибетской рецептурной прописи «пять корней» разработан сухой экстракт, состоящий из корневищ купены душистой (Polygonatum odoratum (Mill) Druce), корней горичника Морисона (Peucedanum morisonii Bess.), корней пиона уклоняющегося (Paeonia anomala L.), корней спаржи лекарственной (Asparagus officinalis L.), плодов якорцев стелющихся (Tribulus terrestris L.), условно названный «Пентафитон». Установлено наличие 14 маркерных компонентов, сырьевым источником которых являются корни горичника Морисона, корни пиона уклоняющегося, корни спаржи лекарственной, плоды якорцев стелющихся (кверцетин-3-О-гентиобиозид, кемпферол-3-О-гентиобиозид, изокверцитрин). Доминирующими соединениями экстракта «Пентафитон» являются кумарины. Полученные фармакологические данные свидетельствуют, что растительное средство «Пентафитон» обладает широким спектром адаптогенной активности, что аргументирует перспективность его дальнейшего исследования и внедрения в клиническую практику в качестве средства, предназначенного для повышения неспецифической сопротивляемости организма, предупреждения утомления при физических и психических нагрузках, а также для повышения работоспособности.
THE NETWORK AND THE STRUCTURE OF COMPLEX, GEOLOGICAL AND HYDROLOGICAL MONUMENTS OF NON-LIVING NATURE OF LVIV OBLAST, UKRAINE
Authors: Brusak Vitaliy , Krychevska Diana
Published: March 2020

This article presents the current list and designed maps of monuments of non-living nature of Lviv region in Ukraine as well as some recommendations and suggestions for its improvement.
The list of monuments of non-living nature is the most numerous category in the structure of the nature reserve fund of Ukraine in general and Lviv region in particular. There are 199 monuments of non-living nature in the Lviv region up to 2019: 2 objects of national importance and 197 of local importance. Depending on the object of protection, the monuments of non-living nature of Lviv region can be divided into botanical (122), hydrological (34), complex (20), geological (19) and forest (4).
The majority of complex nature monuments cover specific forms of relief (individual hills, rocks, caves) with the complex nature conservation value and often historical and cultural importance. The large number of complex monuments of non-living nature is located in Skole and Zolochiv raions, a few in Brody and Yavoriv raions, and just a monument in each of Staryi Sambir, Turka, Drohobych, Kamianka-Buzka, Stryi and Mykolaiv raions.
Geological monuments of non-living nature are organized for the preserve caves, rocks, geological outcrops, erosion deposits, and glacial formations. These natural monuments are distributed in ten administrative raions and in Lviv, generally related to the mountains in Lviv region, the Precarpathian plain and the Podolian upland.
Hydrologic monuments of non-living nature include 29 springs and wells, 3 waterfalls, the peatland and the river outflow. The springs and wells of the mineral waters of the resorts of Morshyn (7), Truskavets (4), Schklo (6), Rozluch (4) and Velykyi Liubin (1) have a special reserved status. A majority of hydrological monuments are located in Stryi (7), Drohobych (6), Yavoriv (6) and Turka (5) raions.
It is proposed to add the following geological monuments of non-living nature such as complex of rocks with caves in Mykolaiv raion, the butte of Chervona Gora in the Zhovkva raion and the complex of rocks in Skole raion to the list of monuments of non-living nature. Further research in the region should include the following objects such as abandoned mining objects, wells and springs of Skhidnytsia resort, drainage of the river Styr.
Key words: monuments of non-living nature; geological monuments; hydrological monuments; Lviv oblast.