bluuebunny/crossref_metadata_2025 huggingface dataset:
Understanding Consumer Behavior with the Use of the Technology Acceptance Model in Online Booking
Authors: Alamsyah Sutantio Raden , Komariyah Siti , Andi Sularso R. , Farid Afandi Mochammad
Published: March 2024

This study aimed to examine consumer buying intention using the Technology Acceptance Model (TAM). This study seeked to determine the direct effect of perceived usefulness, perceived ease of use, and perceived trust on buying intention through online booking applications. This type of research was explanatory, which explained the causal relationship between the variables and used a quantitative approach. The population used in this study was all people who had installed online booking applications. The sampling method of 450 respondents in this study was nonprobability sampling with a purposive sampling technique, whereby the questionnaire was distributed in the form of a survey through social media. Hypothesis testing was carried out using the t-test. Data analysis used multiple linear regression analysis, which was processed with SPSS software. From the results of testing the three hypotheses that had been carried out, it was concluded that the variables of perceived usefulness, perceived ease of use, and perceived trust had a significant and positive effect on the variable of buying intention through online booking applications.
Keywords: consumer behavior, Technology Acceptance Model, online booking
Increasing Employee Engagement through Quality of Internal Communication with a Hybrid Method in One of the Largest Trading Companies in Indonesia
Authors: Handajani Endang Tri , Baskoro Gembong
Published: March 2024

A study on employee engagement conducted by HR Exchange Network.com, sponsored by Workday, after more than a year of the pandemic, stated that there are many changes in work patterns, job opportunities and types of work that develop related to internal communication, employee motivation, organization relations, and industrial relations. This research aimed to determine the effect of hybrid internal communication and employee motivation on employee engagement, either directly or indirectly. The other purpose of this research was to see the effect of organization relations and industrial relations on employee engagement. This quantitative research involved 398 employees of PT XWZ as respondents, using SEM PLS as an instrument to test the hypothesis. The results indicated that the internal hybrid communication method has a positive effect on industrial relations (IR) and organization relations (OR). Employee motivation does not have a positive effect on industrial relationships and organizational relationships; however, OR and IR have a positive effect on employee engagement (EE). OR mediates the relationship between hybrid internal communication and EE while IR does not mediate the relationship between employee motivation and EE.
Keywords: hybrid internal communication, employee motivation, industrial relations, organization relations, employee engagement
Graduate Study with Online Education in the Post-Pandemic Era: An Experiential Case Study
Authors: Baskoro Gembong , Sarwono Edhie , Handajani Endang Tri , Hendriana Dena
Published: March 2024

It is important for the human resources industry to have the ability to overcome existing industrial challenges as well as to prepare for the coming challenges impacted by the changing strategic environment. This includes but is not limited to Industry 4.0, VUCA & BANI World, the COVID-19 pandemic, Society 5.0 and changing geopolitics. To be able to deal with more complex problems requires Higher-Order Thinking Skills (HOTS). Therefore, improving HOTS, especially in the human resources industry, requires a solid partnership between industry and academia. The academic partnership will be meaningful in improving HOTS’s ability through a tailored master’s program known as a multi-disciplinary master’s program (MDMP). MDMP improve the HOTS of industry human resources by combining the strengths of academics and industry. This is an action research developed together between industry and academia and performed in several academic projects towards a master’s degree in various fields. It was concluded, based on the results, that MDMP showed promising results toward the improvement of industry human resources, especially in the ability of HOTS.
Keywords: higher-order thinking skills, academic-industry partnership, multi disciplinary master’s program
Barriers to Knowledge Sharing: A Case Study of Construction Companies in Surabaya
Authors: Agraprana Andhika , Puspa Negara Kartika , Padma Devia Yatnanta
Published: March 2024

Knowledge-sharing (KS) barriers prevent organizations from capitalizing on their skills and knowledge assets. This research aimed to investigate the main barriers to knowledge-sharing and identify the commonly used practice of the knowledgesharing process in the construction company in Surabaya. Data was collected by sending questionnaires to the top management of large contractors (Qualification B) in Surabaya. Fifty-four questionnaires were collected and considered eligible for analysis. The Relative Importance Index (RII) method was used in this research. The results showed that internet/social media, e-mail, and face-to-face interaction are commonly used for knowledge-sharing. The results also showed that the top barrier to knowledge sharing was the lack of top management support and participation. Meanwhile, the top personal barrier was difficulties in generalizing knowledge from one project to another project. This study helped to understand the main barriers to the knowledge-sharing process in construction companies and provided some practical guidance for companies to deal with these barriers. Moreover, this study helped top management to provide strategies to alleviate the barriers to knowledgesharing within their organization in order to achieve the success of construction projects.
Keywords: knowledge-sharing barriers, construction industry, knowledge-sharing practices
The Constitutional Essence of Judicial Cassation in Criminal Cases
Authors:   Presiding Judge of the Second General Jurisdiction Court of Cassation, LL.D., Professor, Mateykovich Maksim S. , Sentyakova Ekaterina S. ,   Justice of the Peace of Judicial District No. 190 of Fili-Davydkovo District of Moscow
Published: March 2024

The article proves that cassation in criminal cases, thanks to the judicial reform carried out in 2018 and amendments to the Constitution of the Russian Federation introduced in 2020, has become a cross-cutting legal institution, including, first of all, the norms of constitutional law, which ensures real constitutional guarantees to ensure the legality of sentences and other decisions in criminal cases based on the principles of fairness, legal certainty, independence of courts and independence of judges.
Labor Function as a Labor-Law Element of Professional Activities of Judges
Authors:   Postgraduate Student of the National Research University Higher School of Economics, Lukhovskaya Yulia O.
Published: March 2024

The article covers the specifics of labor function as a key Labor Law element of the Judge’s professional activity, described as a conjunction of Public Law and Labor Law components. The Author determines compulsory as well as optional elements of labor function of the Judges as a special category employees endowed with special public authority. It is noted that Public Law and Labor Law components of the Judges’ labor function are interconnected, delivering justice as the main function is performed within Labor institutes field.
Produção de uma capital moderna
Authors: Cavalcante de Andrade Julia
Published: March 2024

Partindo de um olhar sobre Brasília, uma capital brasileira que se apresenta moderna desde sua concepção, este artigo visa à compreensão de uma cidade cujo urbanismo, arquitetura e arte resultam de uma série de ideias, valores, discursos e vontades determinadas por grupos dominantes. Tendo como base Mario Pedrosa e Ferreira Gullar como figuras centrais para a construção de uma historiografia crítica de Brasilia, busca-se rediscutir o processo de concepção e representação da capital no período de sua construção e inauguração no campo da arquitetura e das artes plásticas. Assim observamos o quanto e em que aspectos a concepção da capital foi manuseada à vista de se atender ao “gosto do freguês”. Neste caso, considerada as proporções, ao gosto de numerosos e variados fregueses, como as pretensões do júri da comissão julgadora, as predisposições de JK, e principalmente, o gosto do olhar internacional. Uma revisita deste percurso leva à identificação de ambiguidades, lacunas e razões de concessões e demandas atendidas; apresentando como em meio à qualidade estética e conceitual da cidade havia também um terreno fértil em contradições decorrentes dos agenciamentos que a envolveram, em parte não condizentes ao próprio projeto de modernidade almejada.
Cognitive Behavioral Therapy for Depression Integrating Malaysian Culture: A Case Illustration
Authors: Syasyila Kalaivanan , Gin Lim L. , Jamaludin Anne Noor Sri Juwaneeta
Published: March 2024

This clinical case assessed the efficacy of cognitive behavioral therapy (CBT) in treating major depressive disorder in a 26-year-old female, Sara, attributing her depression to pregnancy, financial constraints, parental duties, and emotional stress. Sara had eight sessions of CBT, during which her symptoms were measured using the Hamilton Depression Rating Scale (HAM-D) and the Beck Depression Inventory-Second Edition (BDI-II). Sara’s depressive symptoms dramatically decreased after the intervention, moving her HAM-D and BDI-II scores from moderate to mild depression and from clinically depressed to mild, respectively. The assessment showed improved interest, concentration, energy levels, and a more positive self-perception. Integrating Malaysian cultural elements into CBT, emphasizing family support, community engagement, and spirituality positively impacted Sara. This study emphasizes the value of culturally appropriate CBT for depression as it can help with symptom management, challenging negative thoughts, and bolstering self-esteem. This method identifies and addresses cultural impacts on mental health, recommending the incorporation of cultural aspects in therapy, enhancing relapse prevention and quality of life for Malaysians experiencing depression.
Self- and Proxy-Completion of Quality of Life Assessment in Dementia Care: A Review of Reviews
Authors: Beemer Autumn , Piplica Iva , Sawatzky Richard , Schick-Makaroff Kara
Published: March 2024

Background and Purpose:Quality of life (QOL) assessment invites the perspectives of people living with dementia to be shared with family caregivers and health care providers. A review of reviews was conducted to describe synthesized evidence (i.e., from other reviews) regarding self- and proxy-reports of QOL for this population.Methods:Searches were conducted in four databases. The 25 included articles addressed self- or proxy-rated patient-reported outcome measures, focused on any type of dementia, and were a review or synthesis published in English.Results:Individuals with dementia are largely able to self-report QOL. Proxy-reports are incongruent with self-reports due to various factors, including the proxy-patient relationship and perspective of measurement.Conclusion:When assessing QOL for people with dementia, self-reports are preferred to proxy-reports; however, a combination is recommended.
Psychometric Testing of a Composite Score for Job Satisfaction of Newly Licensed Registered Nurses
Authors: Kurkowski Julie , Dowdell Elizabeth B. , MacKenzie Greenle Meredith
Published: March 2024

Background and Purpose:Inconsistent scaling and inadequate psychometrics on job satisfaction, organizational commitment, and intent to leave among nurses have resulted in studies using a single question to measure these outcomes. Our aim was to psychometrically test a composite measure.Methods:The scales for these variables in the Newly Licensed Registered Nurse Survey (NLRNS) and National Sample Survey of Registered Nurses were re-coded into a composite measure. Utilizing the 2016 NLRNS, we examined reliability and validity indexes.Results:Good internal consistency was demonstrated for the composite measure (α = .93) and the subscales of organizational commitment (α = .86) and intent to leave (α = .88). Exploratory and confirmatory factor analyses resulted in a two-factor solution.Conclusions:Our new composite measure is psychometrically sound and can be utilized for future studies.
“MI AYAM ORA KUDU ANA AYAME”: PEMAKAIAN BAHASA DALAM WACANA HUMOR BOCAH NGAPA(K) YA, PELANGGARAN PRINSIP KERJA SAMA, DAN RELASI HUMORNYA
Authors: Wibowo Ridha Mashudi
Published: March 2024

In addition to serving as a medium of daily communication, the Banyumas dialect can also be used for entertainment, as seen in the television program Bocah Ngapa(k) Ya. This article seeks to identify linguistic quirks and pragmatic maxims that have the potential to be humorous. The data was collected from gathered information through the episode transcripts of the Bocah Ngapa(k) Ya video series, which were downloaded using YouTube Trans7 using the download-transcript-listen-record procedure from April to June 2019. The finding transcriptions were then described utilizing comparison, introspection, and pragmatic equivalent techniques. What linguistic components are crucial for producing the humour effect? How does the principle work? These are questions that the analysis is trying to address.
KATA SERAPAN DARI BAHASA HAKKA DALAM LEKSIKON BAHASA INDONESIA
Authors: Pontoh Manzhuur Daanisy Ahmad Thaahir , Kabul Assa Rahmawati
Published: March 2024

Indonesian language borrowed heavily from languages spoken inside Indonesian territory. The borrowing is caused by language contact between Malay (and now Indonesian) and other languages, including several Sinitic languages that have been spoken for centuries in Indonesia. Hakka Chinese is one of the largest Sinitic languages in Indonesia by the number of speakers, therefore borrowing from Hakka Chinese in Indonesian is bound to happen. The aim of this research is to find borrowings from Hakka Chinese in Indonesian lexicon, also to find semantic changes in those borrowings. Methods in finding the borrowings started from compiling all the possible Hakka loanwords from Hakka lexicons into a wordlist. The wordlist is verified by native Indonesian Hakka Chinese correspondent, and then compared to lemmas in the Kamus Besar Bahasa Indonesia (KBBI) to find any semantic changes. We found that there are 44 loanwords from Hakka Chinese in Indonesian, of which 15 words had semantic changes and 29 others have not any semantic changes.
WANITA “AHMADI” DALAM NOVEL MARYAM: KAJIAN PSIKOLOGI B.F. SKINNER
Authors: Hambali Muhammad , Saharudin Saharudin , Khairussibyan Muh.
Published: March 2024

This study aims to examine the psychology of the main character in the novel Maryam by Okky Madasari in order to determine the response stimulus experienced by the main character and other characters with the literary psychology approach of B.F. Skinner. The data source of this research is the novel Maryam by Okky Madasari. The results showed that the psychology of Maryam's character as a woman "Ahmadi" was closely related to the stimulus response she experienced. The response stimuli include; (1) operant conditioning, found 5 conditioning data, one of which was through the stimulus given by her family, (2) formation, found 8 shaping data, where it is said that the characters Fatimah, Jamil and Zulkhair helped shape Maryam, (3) reinforcement , found data with a total of 7 reinforcers including primary and secondary reinforcement, primary reinforcer responded by Mrs. Maryam and secondary reinforcer when Maryam helped Zulkhair, (4) generalization, found 6 generalization data, where the stimulus from Mr. and Mrs. Zul was then generalized by the character Maryam and (5) avertive stimulus, found 5 avertive stimulus data, one of which was when Maryam's character violated the rules given by her parents. Thus, the psychology of Maryam's character is formed or patterned through these five stages and the most influential in shaping Maryam's "Ahmadi" figure is the stimulus response from Maryam's character and other characters.
SEMIOTICS ANALYSIS OF GENDER STEREOTYPE IN “DOVE” SHAMPOO PRODUCT ADVERTISING: ROLAND BARTHES’ SEMIOTICS APPROACH
Authors: Salim Irfan Hanify
Published: March 2024

This study aims to analyze how stereotypes of women are represented in Dove shampoo advertisements and to analyze the semiotics of gender stereotypes in “Dove” shampoo product advertising using Roland Barthes’ semiotics approach. This study uses a qualitative method by taking primary data sourced from online media ‘YouTube’. The data source is in the form of advertisements for Dove shampoo products in 2022. The advertisement entitled “My Hair is My Crown (Rambutku Mahkotaku) - Dian Sastrowardoyo & Other Women’s Stories About HairBullying”. While the data analysis technique in this study was carried out by identifying signs according to the stages proposed by Roland Barthes (Roland Barthes’ semiotic theory) to determine the meaning of denotation and connotation of advertisements. The results of this study indicate that Dove shampoo advertisement analysis using the Barthes analysis model approach can be explained based on the analysis model by looking at the meaning of denotation and connotation. 5 hairstyles become the outline of the text that strengthens the purpose of depicting the ad including how the woman in the ad is depicted. In addition, each of the women with the 5 hairstyles had experienced hair-bullying because it did not fit the stereotypes of the society (Indonesian people). The five hairstyles are (1) straight hair (just straight), (2) short hair, (3) honeycomb hair, (4) colored hair, and (5) hijab. However, through the shampoo advertisement, Dove wanted to raise awareness about hair-bullying that women often face, through an anti-bullying song titled “My Hair is my Crown (Rambutku Mahkotaku)”. In more detail, Dove wanted to maintain women’s confidence in how to choose and express their hair and break down societal views and stereotypes about what is often considered “beautiful hair”.
JEJAK KOLONIAL CERPEN “BATAVIA YANG TAK SESUAI RENCANA LUCRETIA” KARYA SASTI GOTAMA
Authors: Abdullah Risen Dhawuh
Published: March 2024

This study aims to describe the colonial trace contained in the short story "Batavia yang Tak Sesuai Rencana Lucretia" by Sasti Gotama which was published in Harian Kompas on January 15, 2023 from the perspective of hybridity, mimicry, and ambivalence. The approach used is a postcolonial study developed by Homi K. Bhabha. The qualitative-descriptive method was chosen in this study. The findings in this study are: first, the character Lucretia van der Maas absorbs Eastern cultural values due to living in indigenous areas for quite a long time, namely practicality in dress and this is opposed by Bastiaan van der Maas; secondly, the character Lucretia van der Maas experiences ambivalence in the form of refusing that she is equal to the character Catia while at the same time accepting that on the basis of religion, the moral mimicry as mockery is carried out by the character Catia; and third, the mimicry of language used by the coachman when addressing the figure of Lucretia van der Maas and the response to it which represents a more respectable European nation.
A derivação da Teoria do Estado em Marx
Authors: Maksud Lucas Azevedo
Published: March 2024

A partir das escassas menções de Marx a uma Teoria do Estado, consagrou-se o debate derivacionista, dentre o qual se encontra Helmut Reichelt e outros autores que realizariam, assim, uma Teoria da derivação do Estado moderno. Este artigo recuperará a derivação que tem como base não as categorias políticas tout court, mas sim as categorias econômicas criticadas na obra marxiana; por isso a noção de derivação. Para isso, foi mobilizado uma investigação quanto à caracterização da forma e função do Estado moderno seguida, então, de uma explicitação e dedução do porquê da existência de um aparelho estatal que se desgarra da sociedade e que, ao mesmo tempo, opera a dominação de uma classe sobre a outra.
Tuberculid caused by atypical mycobacteria in an immunocompetent patient: a rare case report
Authors:   Government Medical Collage, Srinagar, India, Parrey A.H. , Koka M. ,   Government Medical Collage, Srinagar, India, Assad M. ,   Government Medical Collage, Srinagar, India, Ismail M. ,   Government Medical Collage, Srinagar, India
Published: March 2024

Tuberculid is defined as cutaneous hypersensitivity eruptions to M. tuberculosis that occur in patients with moderate or high levels of immunity against the microorganism. We report a rare case of long-lasting tuberculid of the nasal bridge caused by atypical mycobacteria. A 35-year-old male patient was diagnosed with pulmonary tuberculosis at the age of 19 years. He received anti-tuberculosis therapy (ATT) for 9 months, and 14 years ago (1 year after completing ATT), a nodular lesion appeared over his right cheek, which gradually spread to the nasal bridge and resulted in facial disfigurement. A biopsy was performed, and histopathology revealed features consistent with lupus vulgaris. PCR for atypical mycobacteria was positive. The patient was treated with clarithromycin, rifampin, and ethambutol. Key words: tuberculid, atypical mycobacteria, immunocompetent, lupus vulgaris
Comparative pharmacological activity of meglumine acridone acetate and lysine acridone acetate during a course of intramuscular administration to mice in a model of acute chlamydial infection
Authors:   S.N.Golikov Scientific and Clinical Center of Toxicology, Federal Medical-Biological Agency of Russia, Saint Petersburg, Russian Federation, Kovalenko A.L. , Alkhutova I.M. ,   LLC "Scientific and Technological Pharmaceutical Company "POLYSAN", Saint Petersburg, Russian Federation, Lycheva N.A. ,   LLC "Scientific and Technological Pharmaceutical Company "POLYSAN", Saint Petersburg, Russian Federation, Pershin V.I. ,   Privolzhsky Research Medical University, Nizhny Novgorod, Russian Federation, Lapshin R.D. ,   Privolzhsky Research Medical University, Nizhny Novgorod, Russian Federation, Mukhina I.V. ,   Privolzhsky Research Medical University, Nizhny Novgorod, Russian Federation
Published: March 2024

According to the World Health Organization, as of 2020, annual infection with C. trachomatis, as register, 129 million people, with the highest incidence observed in group under the age of 25 years. Objective. The study of the pharmacological activity of meglumine acridone acetate and lysine acridone acetate, in the form of a solution for intramuscular administration, in a model of acute chlamydial infection with C. trachomatis in mice. Materials and methods. The studies were performed on 80 mice (male and female) of the DBA/2 line. Modeling of acute chlamydia in mice was carried out by intravenous administration of a live culture of C. trachomatis serovar D. A course (10 days) intramuscular administration of meglumine acridone acetate and lysine acridone acetate began on the 10th day of the experiment. Results. The study found that the administration of meglumine acridone acetate and lysine acridone acetate at doses of 46.4 mg/kg for 10 days in the acute phase of infection caused by C. trachomatis leads to positive dynamics in the clinical picture of the infectious process, weight gain in animals, and a decrease in the number of PCR-positive animals, the concentration of pro-inflammatory cytokines IL-1α and IL-6 and the values of the index of positivity of antibodies to C. trachomatis – IgM. Conclusion. The data obtained indicate the effectiveness of the use of meglumine acridone acetate and lysine acridone acetate in the treatment of infections caused by C. trachomatis. Key words: meglumine acridonacetate, lysine acridonacetate, acute chlamydial infection
Aktivitas Pasar Tradisional Sebagai Inspirasi Motif Fashion Dengan Teknik Digital Printing
Authors: Ariesta Ghina , Kherid Zaitun Y.A , Mudjiati
Published: March 2024

Perancangan ini bertujuan untuk memvisualisasikan serta penyampaian pesan nilai-nilai positif seperti  gotong royong,  interaksi sosial, tekun dan gigih mencari nafkah, masyarakat yang multikultural  dan nilai positif lainnya di tengah meningkatnya pasar modern dan online yang minim lebih interaksi sosial ke dalam desain motif fashion dengan teknik digital print untuk segmentasi masyarakat perkotaan terutama dengan pergerakan mobilitas yang tinggi dan cepat menyerap informasi. Pesatnya pertumbuhan fashion di Indonesia terutama dengan teknik digital print yakni salah satu jenis desain permukaan dengan penambahan corak di atas kain polos (desain struktur). Berdasarkan tujuan tersebut, penciptaan karya tugas akhir ini menggunakan metode pengumpulan data kualitatif antara lain berdasarkan studi pustaka melalui sumber-sumber bacaan, angket atau kuesioner yang perupa bagikan kepada konsumen dengan segmentasi wanita dewasa awal usia 21-30 tahun yang berdomisili di Jakarta, Bogor, Depok, Tangerang, Bekasi, Bandung dan Yogyakarta, observasi jenis kain serta eksplorasi motif dan desain busana. Secara garis besar, penciptaan motif ini menitikberatkan pada eksplorasi pengembangan karakter, penyusunan tata letak elemen desain dan permainan warna yang diolah sehingga tercipta suatu desain yang harmonis sebagai media penyampaian pesan. Hasil akhir motif tersebut diaplikasikan kedalam empat buat karya busana wanita kasual yang masing-masing memiliki tata letak elemen desain dan warna yang berbeda.
Eksplorasi Mainan Seni Dengan Pendekatan Berbasis Praktik
Authors: Fadhillah Alam , Prayitno Eko Hadi
Published: March 2024

Mainan Seni Sebagai Media Representasi Emosi Diri, Skripsi Penciptaan Karya Seni Rupa, Jurusan Pendidikan Seni Rupa. Fakultas Bahasa dan Seni, Universitas Negeri Jakarta. Mainan seni atau mainan desainer merupakan sebuah produk yang dibuat oleh seniman dan desainer yang diproduksi sediri atau dibuat oleh perusahaan mainan kecil dan independen, yang biasanya dalam edisi yang sangat terbatas. Dilakukan pembuatan jurnal pribadi, dirancang dengan mengusung konsep bercerita dan mengekspresikan masing-masing emosi melalui gambar sketsa, menyimpulkan berbagai sketsa yang telah dibuat menjadi satu karakter yang mewakili emosi tersebut dalam masa berkarya, modelling 3D dan dicetak dengan alat cetak 3D. Merespon tren tentang budaya pop dengan ikut berkontribusi melalui karya Mainan Seni yang pada masa kini mulai banyak perancang mainan yang membuat karakter- karakternya sendiri menjadi sebuah mainan seni, produk bisa dinilai dengan gaya yang otentik sebagai produk mainan yang ditargetkan untuk usia dewasa. Produk dirancang bedasarkan survey dan masukan akan kebutuhan masyarakat dan telah teruji di kalangan menengah atas mulai dari usia dewasa awal di wilayah jakarta sebagai target pasar. Tentunya produk mainan seni ini akan menjadi pilihan dan juga jawaban dari tren budaya pop dan memberikan edukasi tentang kondisi psikologis khususnya pada gangguan emosi, sebagai karya seni atau benda koleksi produk mainan seni ini dapat bertahan untuk waktu yang tidak terbatas tergantung dengan teknik perawatannya
Two-Stage Model of Devonian Basic Magmatism in the Vilyui Paleorift (Siberian Platform)
Authors: Polyansky O.P. , Simonov V.A. , Koroleva O.V. , Prokopiev A.V. , Babichev A.V. , Kotlyarov A.V. , Semenov A.N.
Published: March 2024

—We report study results of basic intrusive bodies in the middle Paleozoic Vilyui paleorift (eastern Siberian Platform). Geochemical data for basic sills penetrated by boreholes in the rift’s dike swarms are presented, as well as our data on the time of formation of sills and dikes. We also studied mineral-hosted melt inclusions from a dolerite dike of the Vilyui–Markha dike swarm on the northwestern flank of the Vilyui paleorift. Data on the compositions of homogenous glasses of mineral-hosted melt inclusions yielded the P–T parameters of mantle sources of basic melts responsible for the formation of the Vilyui paleorift gabbro-dolerites. Two depth levels of basic melt generation have been established: 95–65 km at 1480–1400 °C and 55–45 km at 1360–1320 °C. Crystallization of the melts occurred at a shallow depth of 12–4 km with a decrease in temperature from 1185 to 1125 ºС. This occurrence of basic melt sources at two different depths, as well as the heterogeneity of the chemical composition of melt inclusions and their host minerals explains the presence of two pulses of Devonian basic magmatism. Our new numerical thermomechanical model of magma rise during melting of the lithospheric mantle above a mantle plume supports the existence of two chambers at the spinel–garnet peridotite boundary and under the base of the crust, as well as the two-stage nature of Devonian magmatism.
Inflicting Unprecedented Suffering and Destruction: Seven ways the government of Israel is deliberately blocking and/or undermining the international humanitarian response in the Gaza Strip
Authors:   Oxfam International
Published: March 2024

Over five months into the Israeli mass atrocities on the Gaza Strip, in response to the horrific 7 October 2023 attacks by Palestinian armed groups, a meaningful and safe humanitarian response is made impossible by the government of Israel. In this briefing we outline seven fundamental humanitarian access constraints.
Legal Approaches and Regulatory Methods for Fintech in the Guangdong – Hong Kong – Macao Greater Bay Area
Authors: Kuchina Y.
Published: March 2024

Objective: To look at the fintech regulatory policy and regulatory system in the Greater Bay Area through the lens of the Trilemma of Innovation doctrine in order to identify the applicability and extrapolation of existing legal models in the zone of accelerated economic and innovation development in Guangdong, Hong Kong and Macau.

Methods: The article is based on the comparative legal research of the regulation regarding models, existing within the regulatory framework for fintech. For that matter we conduct a generalization, introducing the classification of methods and systems that, in our opinion, can be recognized as the Lego-like systems of instruments.

Results: The research evaluates difficulties that may be faced by the participants within GBA on the way of legal harmonization regarding fintech. Special attention is paid to Hong Kong SAR, being one of the bestknown examples of successful fintech regulation, and to comparing fintech regulation in Mainland China and in SAR (Macau, in particular). The author states that the last amendments to the financial law of Macau SAR also add an element of uncertainty, even though they aim to develop the situation within the framework. The author compares a technocratic approach, according to which fintech regulation is completely national (created only for the domestic market and reflects its structure) and traditional approach to regulation, a part of which is the Trilemma of Innovation. The latter implies the possibility of over-national (international) standardization, including in the form of soft law, which may eliminate the difference in understanding the fintech characteristics, its concepts and scope. Besides, the author analyses the correlation between the concepts of financial regulatory system and financial system of fintech regulation, extrapolation of the existing regulatory framework to the developing market of innovative technological solutions and their various models. The author highlights the regulatory response method, changing during the fintech market evolution, and applied, as a rule, together with other approaches.

Scientific novelty: the article presents a comprehensive review of the different systems of fintech legal regulation in the Guangdong – Hong Kong – Macau Greater Bay Area, whose unique experience demonstrates various trajectories of the fintech market development in southern China within the “One Country – Two Systems” concept.

Practical significance: the main conclusions and proposals resulting from the study are of significant interest for further research, regulatory policy and fintech regulatory system, as Mainland China and the special administrative regions of the Greater Bay Area use different approaches and methods of legal response that have no analogues in the modern world.
Impact of New Technologies on Economic Behavior and Consumer Freedom of Choice: from Neuromarketing to Neuro-Rights
Authors: Sposini L.
Published: March 2024

Objective: to identify the possibilities for an adequate response of the existing legal regime to the various challenges posed to European law by artificial intelligence systems underlying neuromarketing techniques.

Methods: the study is based on the risk-oriented approach, formal-logical, formal-legal and comparative-legal methods, as well as on the method of legal forecasting, in order to identify the problems of legislation caused by the emerging technologies capable of recognizing human emotions and using them to control consumer behavior, and to propose ways to solve them.

Results: the conducted research provides a brief overview of the most widely used neuromarketing techniques used by algorithms and machine learning. These allow identifying points of cognitive and emotional vulnerability, collecting and processing data, and then building the most effective marketing techniques that push a consumer to choose a certain product or service. Ethical problems are analyzed which arise from the use of neuromarketing techniques in relation to some basic values such as individual independence, human dignity, and freedom of choice. The subtle line is shown between techniques that manipulate consumer behavior (manipulation technique) and those that, on the contrary, have a persuasive effect, which in itself does not make them illegal (persuasion technique). An overview of the existing legal framework is presented, as well as case law from both the European Court of Justice and national courts of member states with a particular focus on the Unfair Commercial Practices Directive, the EU General Regulation on the Protection of Personal Data (hard law), and codes of ethics (soft law).

Scientific novelty: the paper points out the transformation of traditional legal categories and important problem points of the existing regulation due to the growing recognition of the potential of neuromarketing as a tool capable of explaining and predicting consumer behavior, as well as influencing the economic behavior of the subjects of relations.

Practical significance: the obtained conclusions and proposals can be taken into account in improving the regulation of artificial intelligence in terms of its safety and reliability, increasing trust in the system, given the need to protect ethical principles and maintain fundamental values.
Funding and its impact on the administration and organisational efficiency of technical vocational education and training institutions
Authors: Mack Abede
Published: March 2024

In the present study, the author examines how the lack of funding can impact the administration and the organisational efficiency of technical vocational education and training (TVET) institutions (I). The research examines human capital development and TVET as instruments for propelling growth and development and contributing to Trinidad and Tobago’s (T&T) economic and social advancements. The study explored how TVETIs can be a central pillar in the progress of T&T’s development. The research material consists of 10 interviews with educational experts from four postsecondary TVETIs in T&T and the chief executive of T&T TVET’s regulatory body. Focus groups and individual interviews were conducted with the leading regulator, instructors, managers, and a curriculum expert. The author utilised thematic analysis in the research by adopting a deductive approach. The data revealed several challenges that engulf the administration and management of TVETI in T&T, mainly because of financial woes. Three themes emerged from the data: Funding for Administration, Funding for Human Capital Development and Funding for Organisational Efficiency. Insightful revelations were unearthed from the educational experts, which were generated from the data which provide an in-depth perspective on the administration and management of TVET in T&T. The results show that T&T’s education experts see funding as a significant challenge. Many argue that a lack of funding severely impacts their institutions, which erodes human capital development growth. The study concludes that a lack of funding can severely and has impacted TVET in several ways. An absence or a lack of funding brought the closure of top-notch schools used in the training and growth of teachers for the educational system. Human capital development and TVET were also highlighted as essential tools for economic and social deprivation. However, a better approach is needed to finance TVET moving forward.
A comparative whole genome comparison analysis of Helicobacter pylori from gastric cancer and gastritis in China setting
Authors: Kong Pengfei , Yan Yong-hao , Duan Yan-tao , Fang Yan-tian , Dou Yi , Xu Yong-hu , Xu Da-zhi
Published: March 2024

Background: This study aimed to explore and compare the differences in the genomics and pathogenicity of Helicobacter pylori (H. pylori) strains derived from the gastric cancer (GC) and gastritis (GI) in the Chinese population.
Methods: We sequenced 12 H. pylori from GC and GI patients in china by whole genome sequencing. 20 H. pylori sequencing data from other regions of the world were obtained from the public platform as reference genes. Then, the evolutionary tree was drawn based on multi-omics, and the differences of virulence factors (VF) and gene function were analyzed
Results: In GC stains, the 1544-1640 coding genes, with a total length of 1,549,790-1,605,249 bp, were predicted. In GI stains, the 1552-1668 coding genes, with a total length of 1,552,426-1,665,981 bp, were identified. In addition, the average length of coding genes in GC and GI strain, was approximately 1594 (90.91%) and 1589 genes (90.81%), respectively. We found that the VFs predicted by the two cohort strains had high consistency, but their cagA status was significantly different. Additionally, the clustering results indicated that there were significant differences in core Single Nucleotide Polymorphism (SNP) between GC and GI strains, but no significant differences in homologous proteins and gene island prediction between the two strains. Subsequently, the results of pan-genomic and Average Nucleotide Identity (ANI) analyses suggested that GC, GI and other reference H. pylori strains had high homology consistency. Furthermore, the gene function annotation results suggested that the H. pylori strains of GC and GI also had high similarity in gene function, and their specific gene functions were mainly concentrated in the process of metabolism, transcription and repair.
Conclusions: GC and GI patient-derived H. pylori have some differences in VF and SNP, but they also have high homologous consistency at other level of the genome in Chinese population.
Repetitive stability study of Remdesivir/Cyclodextrin complex on ISS
Authors: Dormán György , Buchholcz Balázs , Puskás István , Szabó Pál , Varga Erzsébet , Szente Lajos , Keserű György M. , Darvas Ferenc
Published: March 2024

Stability assessment of drugs in space is particularly important for future missions., In space there are multiple factors, such as the variability of the conditions (radiation, microgravity, vacuum etc.) that could affect the reliability and reproducibility of the data. Therefore, we investigated the stability of an anti-Covid drug formulation, Remdesivir (RDV) sulfobutylether-beta-cyclodextrin (SBECD) complex, in two separate flight experiments on the International Space Station (ISS). While HPLC/MS studies revealed no degradation of the cyclodextrin excipient in any of the samples investigated in both missions, RDV purity analysis of the RDV/SBECD complex after the first mission revealed different stabilities and altered degradation in space and on Earth. This latter interesting finding was not supported by the second mission, where no differences in the drug stabilities were identified. This anomaly highlighted the importance of standardization together with increased control of the variable parameters during the entire space missions and the terrestrial control experiments.
Estimation of water saturation based on optimized models in tight gas sandstone reservoirs: A case study of Triassic Xujiahe Formation in northwestern Sichuan Basin
Authors: Xia Xiaoyong , Han Bing , Xie Bing , Lai Qiang , Wang Yuexiang , Zhu Shaowu
Published: March 2024

Water saturation estimation faced a great challenge in tight gas sandstone reservoirs because of the effect of pore structure and strong heterogeneity to rock resistivity. The classic Archie’s equation cannot be always well used. To quantify the effect of pore structure to rock resistivity in tight gas sandstones, taking the Triassic Xujiahe Formation of northwestern Sichuan Basin as an example, 35 core samples were recovered and applied for resistivity experiments in laboratory under the simulated formation temperature and pressure environment, and 18 of them were simultaneously applied for nuclear magnetic resonance (NMR) and high-pressure mercury injection (HPMI) experimental measurements. Relationships between rock pore structure and resistivity parameters were analyzed. The results clearly illustrated that cementation exponent (m) and saturation exponent (n) were heavily affected by pore structure. Rocks with superior pore structure contained relative higher cementation exponent and lower saturation exponent, and vice versa. Afterwards, we raised a parameter of pore size index, which was defined as the ration of macropore and micropore percentage contents, to reflect rock pore structure, and established a model to calculate optimal saturation exponent from NMR data. Meanwhile, various cementation exponent prediction model was also raised by combining with porosity and irreducible water saturation (Swirr). By combining with calculated cementation exponent and saturation exponent, we optimized the Archie’s equation to predict water saturation in our target tight gas sands. Field examples illustrated that the predicted cementation exponent and saturation exponent matched well with core-derived results. The absolute errors between predicted cementation exponent and saturation exponent with core-derived results were lower than 0.05 and 0.07, separately. By using the optimized Archie’s equation, water saturations were precisely predicted from well logging data in our target tight gas sandstone reservoirs.
Prevalence and epidemic pattern of ecdemic multidrug-resistant tuberculosis during 2012- 2022 in Hangzhou, China: implication for public health strategies
Authors: Li Qingchun , Wu Yifei , Cheng Qinglin , Lu Min , Huang Yinyan , Bai Xuexin , Jia Qingjun , Fang Zijian , Ai Liyun , Jiang Nan , Lao QiuFeng , Xie Li , Chen Junfang
Published: March 2024

Background
To assess the prevalence and epidemic pattern of multidrug-resistant tuberculosis in Hangzhou City, Zhejiang Province, China during 2012–2022.
Methods
All the tuberculosis cases undergoing drug susceptibility testing during 2012–2022 were included in this study. De-identified information was extracted from the electronic database Tuberculosis Information Management System for analysis of drug resistance prevalence in Hangzhou and ecdemic multidrug-resistant tuberculosis which originated from other regions. Chi-square tests were used to compare drug resistance rates between different groups, while Chi-square tests for trend were used to evaluate the change of drug resistance rates over the years of 2012–2022. The sources and destinations of ecdemic multidrug-resistant tuberculosis were illustrated using a Sankey diagram.
Results
Of 21,127 cases included in this study, 1119 (5.3%) were multidrug-resistant tuberculosis. A significant decline in multidrug-resistant tuberculosis rates was observed during 2012–2022. There was a significant difference in multidrug-resistant tuberculosis rates among immigrant population and local residents in Hangzhou City. Of 1119 multidrug-resistant tuberculosis cases, 515(46%) were ecdemic multidrug-resistant tuberculosis cases, of which 277(53.8%) were from other parts of Zhejiang Province and 238(46.2%) were from other provinces in China. Anhui, Jiangxi and Sichuan were among top three provinces which were the source of ecdemic multidrug-resistant tuberculosis cases. Three districts including Xiaoshan, Shangcheng and Linping districts had the most cases in Hangzhou. The proportion of ecdemic multidrug-resistant tuberculosis cases in Binjiang, Xiaoshan, Qiantang and Linping districtalso exceeded 30% of total cases.
Conclusions
Multidrug-resistant tuberculosis prevalence has been declining in Hangzhou. Migrant population contributed to a significant potion of cases in Hangzhou. Interventions should be tailed to local and migrant residents.
Effects of walking on epigenetic age acceleration: a Mendelian randomization study
Authors: Chen Guanyi , Liu Chao , Xia Yu , Wang Pingxiao , Zhao Ziyue , Li Ao-yu , Zhou Chuqiao , Xiang Cheng , Zhang Jialin , Zeng Yi , Gu Peng , Li Hui
Published: March 2024

Introduction
: Walking stands as the most prevalent physical activity in the daily lives of individuals and is closely associated with physical functioning and the aging process. Nonetheless, the precise cause-and-effect connection between walking and aging remains unexplored. The epigenetic clock emerges as the most promising biological indicator of aging, capable of mirroring the biological age of the human body and facilitating an investigation into the association between walking and aging. Our primary objective is to investigate the causal impact of walking with epigenetic age acceleration (EAA).
Methods
We conducted a two-sample two-way Mendelian randomization (MR) study to investigate the causal relationship between walking and EAA. Walking and Leisure sedentary behaviour data were sourced from UK Biobank, while EAA data were gathered from a total of 28 cohorts. The MR analysis was carried out using several methods, including the inverse variance weighted (IVW), weighted median, MR-Egger, and Robust Adjusted Profile Score (RAPS). To ensure the robustness of our findings, we conducted sensitivity analyses, which involved the MR-Egger intercept test, Cochran’s Q test, and MR-PRESSO, to account for and mitigate potential pleiotropy.
Results
The IVW MR results indicate a significant impact of usual walking pace on GrimAge (BETA = -1.84, 95% CI (-2.94, -0.75)), PhenoAge (BETA = -1.57, 95% CI (-3.05, -0.08)), Horvath (BETA = -1.09 (-2.14, -0.04)), and Hannum (BETA = -1.63, 95% CI (-2.70, -0.56)). Usual walking pace is significantly associated with a delay in Epigenetic Aging Acceleration (EAA) (P < 0.05). Moreover, the direction of effect predicted by the gene remained consistent across RAPs outcomes and sensitivity MR Analyses. There is a lack of robust causal relationships between other walking conditions, such as walking duration and walking frequency, on EAA (P > 0.05).
Conclusion
Our evidence demonstrates that a higher usual walking pace is associated with a deceleration of the acceleration of all four classical epigenetic clocks acceleration.