bluuebunny/crossref_metadata_2025 huggingface dataset:
The problem of cognitive significance - a solution and a critique
Authors: Cukljevic Filip
Published: June 2018

In this paper I will deal with the solution to the problem of cognitive
significance offered by the so-called new theorists of reference, as well as
with the critique of that solution given by Howard Wettstein. I will claim
that the answer to this critique provided by John Perry is not sufficiently
convincing. First, I will clarify some relevant concepts in order to present
the problem of cognitive significance in a clear manner. Then I will expose
the solution to the problem offered by Perry and David Kaplan. After that, I
will present Wettstein?s critique of that solution. Subsequently, I will
also analyze Perry?s attempt to defend against this critique. Finally, I
will discuss the extent to which Perry?s attempt is successful. It will be
shown that it is significantly not so.
Insulin Regulates Lipolysis and Fat Mass by Upregulating Growth/Differentiation Factor 3 in Adipose Tissue Macrophages
Authors: Bu Yun , Okunishi Katsuhide , Yogosawa Satomi , Mizuno Kouichi , Irudayam Maria Johnson , Brown Chester W. , Izumi Tetsuro
Published: June 2018

Previous genetic studies in mice have shown that functional loss of activin receptor–like kinase 7 (ALK7), a type I transforming growth factor-β receptor, increases lipolysis to resist fat accumulation in adipocytes. Although growth/differentiation factor 3 (GDF3) has been suggested to function as a ligand of ALK7 under nutrient-excess conditions, it is unknown how GDF3 production is regulated. Here, we show that a physiologically low level of insulin converts CD11c− adipose tissue macrophages (ATMs) into GDF3-producing CD11c+ macrophages ex vivo and directs ALK7-dependent accumulation of fat in vivo. Depletion of ATMs by clodronate upregulates adipose lipases and reduces fat mass in ALK7-intact obese mice, but not in their ALK7-deficient counterparts. Furthermore, depletion of ATMs or transplantation of GDF3-deficient bone marrow negates the in vivo effects of insulin on both lipolysis and fat accumulation in ALK7-intact mice. The GDF3-ALK7 axis between ATMs and adipocytes represents a previously unrecognized mechanism by which insulin regulates both fat metabolism and mass.
High Diabetes Distress Among Ethnic Minorities Is Not Explained by Metabolic, Cardiovascular, or Lifestyle Factors: Findings From the Dutch Diabetes Pearl Cohort
Authors: Özcan Behiye , Rutters Femke , Snoek Frank J. , Roosendaal Mandy , Sijbrands Eric J. , Elders Petra J.M. , Holleman Frits , Pijl Hanno , Tack Cees J. , Abbink Evertine J. , de Valk Harold W. , Wolffenbuttel Bruce H.R. , Stehouwer Coen D.A. , Schaper Nicholas C. , Dekker Jacqueline M. , Schram Miranda T.
Published: June 2018

OBJECTIVE

Diabetes distress among patients from ethnic minorities is still poorly understood. We investigated the association between ethnicity and diabetes distress among ethnic minority groups of people with type 2 diabetes in the Netherlands, focusing on the possible effects of glycemic control, lifestyle factors, cardiovascular risk factors, and diabetes complications.

RESEARCH DESIGN AND METHODS

Cross-sectional data from the Dutch Diabetes Pearl cohort included people with type 2 diabetes from primary, secondary, and tertiary diabetes care programs. We used the 20-item Problem Areas in Diabetes Survey (PAID) scale to assess diabetes distress; a score ≥40 is considered to represent high distress. Ethnicity was estimated on the basis of country of birth. Sociodemographic and lifestyle data were self-reported; cardiovascular and metabolic data were retrieved from medical charts. Logistic regression analysis determined the association between ethnicity and diabetes distress, with Caucasians as the reference group.

RESULTS

Diabetes distress scores and ethnicity were available for 4,191 people with type 2 diabetes: 3,684 were Caucasian, 83 were Asian, 51 were Moroccan, 92 were African, 134 were Latin American, 46 were Turkish, and 101 were Hindustani-Surinamese. Overall, participants in minority groups had worse health outcomes than those of Caucasian descent, and diabetes distress was more prevalent (ranging from 9.6 to 31.7%, compared with 5.8% among Caucasians), even after adjusting for age, sex, education level, alcohol use, smoking, BMI, lipid profile, HbA1c, medication use, and the presence of diabetes complications.

CONCLUSIONS

Among people with type 2 diabetes in the Netherlands, ethnicity is independently associated with high diabetes distress. Further research is warranted to explain the higher prevalence of diabetes distress in minority groups and to develop effective interventions.
Public Preferences regarding Data Linkage for Health Research: A Discrete Choice Experiment
Authors: Aitken Mhairi , McAteer Gareth , Davidson Sara , Frostick Clive , Cunningham-Burley Sarah
Published: June 2018

The potential for data collected in the public and private sector to be linked and used in research has led to increasing interest in public acceptability of data sharing and data linkage. The literature has identified a range of factors that are important for shaping public responses and in particular has noted that public support for research conducted through data linkage or data sharing is contingent on a number of conditions being met. In order to examine the relative importance of these conditions a Discrete Choice Experiment (DCE) was conducted via an online questionnaire among members of Ipsos MORI’s online panel in Scotland. The survey was completed by 1,004 respondents. Overall the two most influential factors shaping respondents’ preferences are: the type of data being linked; and, how profits are managed and shared. The type of data being linked is roughly twice as important as who the researchers are. There were slight differences across age groups and between genders and slight differences when comparing respondents with and without long term health conditions. The most notable differences between respondents were found when comparing respondents according to employment and working sector. This study provides much needed evidence regarding the relative importance of various conditions which may be essential for securing and sustaining public support for data-linkage in health research. This may be useful for indicating which factors to focus on in future public engagement and has important implications for the design and delivery of research and public engagement activities. The continuously evolving nature of the field means it will be necessary to revisit the key conditions for public support on an ongoing basis and to examine the contexts and circumstances in which these might change.

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Propuesta de estrategias de aprendizaje acorde a los estilos de aprendizaje de los estudiantes de Ingeniería de la ESCOM del IPN / Instruments to evaluate the competences of the professors who teach the COE Learning Unit in the ESCOM of the IPN
Authors: Pérez Vera Monserrat Gabriela , Leyva López Hermelinda Patricia , Ocampo Botello Fabiola , De Luna Caballero Roberto
Published: June 2018

Los profesores tenemos presente que nuestros estudiantes son muy diversos en cuanto a sus gustos, preferencias, situación socioeconómica, cultura, así como la forma de recibir la información y procesarla, lo que nos permite reflexionar sobre la forma de llevar a cabo las actividades de enseñanza y aprendizaje en el salón de clases. Es por ello por lo que este trabajo describe una experiencia en donde se identifican los estilos de aprendizaje, de acuerdo al modelo de Richard Felder, de las cinco categorías polares, en los estudiantes del cuarto nivel del mapa curricular, lo cual equivale al séptimo y octavo semestre, que cursan la unidad de aprendizaje Liderazgo y Desarrollo Profesional de la carrera de Ingeniería en Sistemas Computacionales que se ofrece en la Escuela Superior de Cómputo (ESCOM) del Instituto Politécnico Nacional (IPN).Para realizar la presente investigación se realizó un estudio descriptivo, de corte cuantitativo, con una muestra intencional de alumnos; y para conocer los estilos de aprendizaje de los estudiantes, fue aplicado, mediante la técnica de recuperación de información de campo, el instrumento de la entrevista, el cual se realizó a los tres grupos.Los resultados obtenidos con mayor porcentaje fueron el activo, el intuitivo, visuales y secuenciales, sugiriendo a cada estilo algunas estrategias de aprendizaje.
A FORMAÇÃO DO PROFESSOR COMO EDUCADOR DE JOVENS E ADULTOS: UMA INVESTIGAÇÃO NOS PROJETOS PEDAGÓGICOS DE CURSOS PRESENCIAIS DE LICENCIATURA EM MATEMÁTICA DE INSTITUIÇÕES DE ENSINO SUPERIOR PÚBLICAS DA REGIÃO AMAZÔNICA
Authors: Cristiano Belmar Cesar , Denise Wielewski Gladys
Published: June 2018

A Educação de Jovens e Adultos (EJA) é um dos possíveis espaços de atuação do professor. Os estudantes que frequentam as salas de aula da EJA apresentam características ímpares que os diferenciam daqueles pertencentes a outras modalidades de ensino. Diante dessa realidade, é de fundamental importância que no decorrer da licenciatura o futuro professor tenha acesso a conhecimentos referentes ao contexto dessa modalidade de ensino. Esta pesquisa é de abordagem qualitativa e se caracteriza como um estudo exploratório cujo objetivo foi analisar se os projetos pedagógicos de cursos presenciais de licenciatura em Matemática de instituições públicas da região amazônica contemplam a temática da EJA. Para obtenção dos dados foram analisados 23 projetos pedagógicos de cursos presenciais de licenciatura em Matemática de instituições de ensino superior públicas da região amazônica (Acre, Amapá, Amazonas, Maranhão, Mato Grosso, Pará, Rondônia, Roraima e Tocantins), obtidos nos sites dessas instituições e/ou via e-mail. Para interpretação e análise dos dados utilizou-se o método da análise de conteúdo. Os resultados indicam que tal temática ainda é incipiente nas propostas de formação dos professores nos cursos investigados.
SABERES DOCENTES E RECURSOS EDUCACIONAIS ABERTOS: UMA ANÁLISE DA PRESENÇA DESSAS TEMÁTICAS NOS ENCONTROS DE DEBATES SOBRE O ENSINO DE QUÍMICA (2015 E 2016)
Authors: Eismann de Castro Ronaldo , Rocio Fontoura Teixeira Maria do
Published: June 2018

A partir das importantes contribuições das produções científicas originadas dos Encontros de Debates de Ensino de Química (EDEQs) dos anos de 2015 e 2016, entende-se a relevância da realização de um trabalho com cunho bibliográfico a seu respeito. Para atender a essa demanda, foi realizada uma investigação exploratória dos conteúdos e dos temas dessas produções. Sendo assim, este artigo visa apresentar os resultados do mapeamento e da análise de dados dos trabalhos submetidos nesses dois encontros, a fim de sistematizar os saberes docentes e os recursos educacionais abertos abordados dentro das temáticas apresentadas. O resultado da análise permitiu concluir que os temas relacionados ao saber docente e aos recursos educacionais abertos estão inseridos na grande maioria dos trabalhos, sobressaindo-se, no período verificado, os assuntos relacionados ao saber docente.
LETRAMENTO DIGITAL: UMA INVESTIGAÇÃO DA TEORIA À PRÁTICA DOCENTE DE PROFESSORES DO ESTADO DE MATO GROSSO
Authors: Aparecida Reis Maria , Sheuer Nantes Eliza Adriana , Lima Antunes Maciel Cilene Maria
Published: June 2018

O presente estudo é parte de uma pesquisa realizada com 39 professores da educação pública de Mato Grosso e possui como objetivo analisar e verificar se os projetos de formação continuada do Centro de Formação e Atualização dos Profissionais da Educação Básica (CEFAPRO), do município de Cuiabá, estado de Mato Grosso, contemplaram o letramento digital dos professores, caso contemple, em que medida contribuem para a prática pedagógica no contexto tecnológico vigente. A pesquisa foi construída em uma abordagem qualitativa e os instrumentos de coleta de dados foram o questionário e os documentos oficiais da Secretaria de Estado de Educação, Esporte e Lazer (SEDUC). A ancoragem epistemológica baseou-se nos estudos de Moran (2017), Rojo (2012), Soares (2009), dentre outros pesquisadores que versam sobre tecnologia, letramento digital e ensino. Os dados foram categorizados tendo os fragmentos dos discursos dos professores organizados seguindo orientações básicas da Análise de Conteúdo proposta por Bardin (2011). Os resultados indicaram que a formação recebida contribuiu com a prática pedagógica e que a maioria dos entrevistados considera-se apta para trabalhar com os recursos tecnológicos como ferramenta pedagógica, contudo ainda há necessidade de formação, sobretudo na área de letramento digital.
SENTIDOS DE JOVENS VIVENDO COM HIV FRENTE AOS ESTIGMAS, PRECONCEITOS E VULNERABILIDADES EM AMBIENTE EDUCACIONAL
Authors: Francisco dos Anjos Degmar , Monteiro da Fonseca José Henrique , Ostelony da Silva Jessika Karoliny
Published: June 2018

No presente artigo se objetiva analisar as vivências, no ambiente educacional, de jovens com diagnóstico positivo para HIV, debatendo a presença dos estigmas e preconceitos diante do HIV/Aids, apontando seus traços históricos presentes no ambiente educacional. Perante tal fenômeno realizou-se estudo com 12 jovens na faixa etária entre 15 a 24 anos no município de Cuiabá - MT. A pesquisa, de cunho qualitativo, investigou os sentidos desses jovens vivendo com HIV no ambiente educacional. Com especial atenção ao processo ensino-aprendizagem e às relações de poder – estigmas e preconceitos – diante de seus pares. Trabalhou-se enquanto olhar teórico-metodológico com o Construcionismo Social por meio da análise de repertórios linguísticos investigando a produção de sentidos enunciados por práticas discursivas. Observaram-se nos resultados, relatos de sujeitos que foram vítimas de estigmas, preconceitos e/ou - como aparece unânime em meio às vozes - que provavelmente seriam vítimas de preconceitos e isolamento caso alguém soubesse de sua condição soropositiva, relatando o medo de se expor para colegas e professores. Aparecem consonâncias, também, nas constatações acerca do silenciamento escolar diante de temáticas como HIV/AIDS/Preconceitos, haja vista que nas poucas vezes que houve algum trabalho relacionado a essa questão, limitaram-se epidemiologicamente às aulas de biologia. Tais ambientes mostram-se vulneráveis, carentes de respaldo - enquanto formação docente - para lidar com essas realidades de nossa contemporaneidade, bem como para abarcar assuntos tão importantes para atenuação das vulnerabilidades sexuais de nossa juventude.
PRÁTICA DOCENTE E BUROCRACIA DE NÍVEL DE RUA: UM DIÁLOGO INTERDISCIPLINAR PROMISSOR
Authors: Costa Filho José Vinícius da , Gonçalves-Costa Lyssa , Vinícius da Costa José
Published: June 2018

Este artigo propõe examinar a prática docente mediante a teoria dos burocratas de nível de rua. Logo, o presente estudo é um esforço para dialogar pressupostos da área de educação com a área de políticas públicas visando contribuir com a agenda de pesquisa que trata da prática docente. Metodologicamente, se perfaz em uma pesquisa descritiva norteada pela revisão da literatura que coloca em um mesmo plano epistemológico a prática docente e a burocracia de nível de rua. Esta pesquisa resultou em uma proposta de abordagem para análise dos fenômenos da educação atinentes à prática docente conectando-a com seu viés de política pública; para tal desiderato, foca-se nos funcionários que trabalham diariamente nesse contexto em seu nível operacional.
EDUCAÇÃO BÁSICA E A PRÁTICA DOCENTE NA CONCEPÇÃO DE FREIRE E STEINER: FUNDAMENTOS DA LDB E DO PPP DA ESCOLA LIVRE PORTO CUIABÁ
Authors: Paula Martins Cálita Fernanda de , Aparecida Romanelli Rosely
Published: June 2018

As discussões apresentadas neste estudo tratam das primeiras aproximações em relação à pesquisa desenvolvida no âmbito do mestrado. Todavia, o presente artigo tem como principal objetivo discutir acerca da educação básica e da prática docente na concepção de Freire e Steiner, tendo por base os princípios da Lei de Diretrizes e Bases da Educação Nacional (LDB) - 9394/96 e sua aplicação no Projeto Político e Pedagógico (PPP) da Escola Livre Porto Cuiabá. Para o desenvolvimento deste estudo foi realizado uma pesquisa de abordagem qualitativa. Quanto aos procedimentos, uma pesquisa bibliográfica e documental. Por se tratar de uma pesquisa documental foi feita análise do PPP de uma instituição Waldorf. Quanto ao procedimento bibliográfico foi utilizado enquanto referencial teórico: Santos e Romanelli para discutir acerca dos princípios da Pedagogia e da Antroposofia; Freire e Steiner para fundamentar a discussão quanto à concepção da prática docente; Oliveira para discutir os fundamentos da LDB, Lanz na intenção de apresentar o perfil e qualidades do professor Waldorf, entre outros autores. Todavia, buscamos na Pedagogia saberes que poderão contribuir para a educação em uma perspectiva humanizadora, tendo como princípio auxiliar na formação de seres humanos, promovendo o desenvolvimento saudável e harmônico do querer, sentir e pensar.
O OLHAR CUIDADOSO DO EDUCADOR: CAMINHOS PERCORRIDOS
Authors: Oestreich Laura , Costa Daniela , Goldschmidt Andréa Inês
Published: June 2018

O estágio curricular supervisionado é parte essencial na formação inicial do educador. Ao passar por essa etapa o futuro docente vivencia o cotidiano escolar, explorando sua realidade. Trata-se de um momento de angústias, alegrias, encontros e desilusões e no decorrer desse processo ocorre o afloramento da identidade docente. Nesse sentido, as boas relações entre educador e educando são essenciais e tendem a auxiliar nos processos de ensino-aprendizagem. Diante disso, o artigo tem como objetivo relatar as vivências do estágio em licenciatura e, a partir desse, discutir e provocar reflexões de como as relações afetivas influenciam no aprendizado dos educandos. Busca ainda sinalizar para a importância dessas relações, da empatia e do olhar cuidadoso do educador perante os educandos e suas infinitas inquietações, contribuindo para a construção docente de outros estagiários de licenciatura. Por meio de espaços de discussão e aulas contextualizadas com a realidade dos educandos, aponta-se que a construção de um ambiente de confiança entre os atores envolvidos nos processos educativos facilita o aprendizado dos educandos. A percepção de elementos que estejam atrapalhando esse processo fortalece a ideia de que a função docente não é meramente de ensinar, mas também de auxiliar o educando a se descobrir enquanto ser humano.
O ESTÁGIO CURRICULAR SUPERVISIONADO NO CURSO DE LICENCIATURA EM MATEMÁTICA: RELAÇÕES ENTRE SABERES E IDENTIDADE DOCENTE
Authors: Quadros Vera Cristina de , Kochhann Maria Elizabete Rambo
Published: June 2018

No ano de 2016, foi realizada uma pesquisa de mestrado, na área de Ensino, que analisou a contribuição do estágio curricular supervisionado no processo de construção dos saberes docentes dos estagiários. Dessa pesquisa, o presente artigo propõe-se um recorte do trabalho analítico, a fim de socializar as relações entre os saberes docentes e a construção da identidade docente que foram reveladas nos discursos dos estagiários. A pesquisa, de natureza qualitativa, foi realizada com os sete estagiários do curso de Licenciatura em Matemática do Instituto Federal de Educação, Ciência e Tecnologia de Mato Grosso Campus Campo Novo do Parecis, no decorrer do ano de 2016. Os dados foram produzidos em entrevistas semiestruturadas, submetidas aos procedimentos analíticos da Análise Textual Discursiva, proposta por Moraes e Galiazzi (2016). Analisou-se que os estágios permitiram aos estagiários a primeira vivência da prática da profissão de professor e, com isso, assumiram um novo lugar, experimentando um novo olhar, o de ver-se professor. Puderam conhecer, sentir e ver-se em um novo lugar social e subjetivo, saindo do lugar de alunos para o lugar de professores. Ainda que de forma incipiente, mediatizados pelo outro (professores regentes, alunos, familiares, instituições de ensino), cada estagiário iniciou seu processo identitário, sua construção de maneiras de ser e de estar na profissão.
Influence of Crosslinking Agent Concentration on The Microencapsulation Parameters of Collagen Hydrolysate-Walled Microcapsules
Authors: Aslan Ahmet , Ocak Bugra
Published: June 2018

Despite being a lot of discussion, a large amount of chrome tanned leather is still being tanned in the world. After tanning with chrome, chrome solid leather wastes occurred. These chrome wastes arise during mechanical processes such as trimming, shaving, buffing and splitting. These solid wastes containing trivalent chromium and may be oxidized to hexavalent chromium by the appropriate conditions in the landfill areas. Increasing environmental awareness and regulations have been making great pressure on the leather industry. Nowadays, solid leather wastes tanned with chromium are assessed by hydrolysis with the enzyme in high alkaline media and can subsequently be used for several applications. However, there is still no definitive solution to these chromed solid leather wastes. In this study, microcapsules of collagen hydrolysate cross-linked with glutaraldehyde containing Lavender essential oil were prepared by coacervation method. The influence of crosslinking agent concentration on the oil load (%), oil content (%) and encapsulation efficiency (%) of lavender oil microcapsules were investigated. As the crosslinking agent concentration increased, the oil load (%) decreased but oil content (%) and encapsulation efficiency (%) of microcapsules increased. The best result obtained by using 5 g of collagen hydrolysate, 7 ml of glutaraldehyde and 7 ml of lavender oil.
Competence-Oriented Task as Means of Quality Improvement of Mathematical Education
Authors: Aigul Dauletkulova , Nurgul Kurmanbekkyzy
Published: June 2018

Integration of Kazakhstan into the world educational space makes it necessary to align with the requirements of the state and society to orient the education of the younger generation on the development of competencies that promote the concept of "education through life". Significant changes in the priorities in school education in the world in recent years require a reorientation to a competence approach, continuous self-education, mastering new information technologies, the ability to cooperate and work in groups.

The purpose of our research is to improve the quality of school mathematics education with the help of competence-oriented assignments.

For the analysis of the analyzed targets, the analysis of the native and chemical methapods is analyzed; the systematic analysis of the mathematical encounters and the reconstruction of the infectious information with the help of hypotheses and analgesia, comparison and hypnotism, analysis and synthesis, modeling and mental ex- periment; Diagnostic methods with the goal of designing the formation of coarse mnogoapektnyh central design of the person; the isolation of the criteria for the design of a diagonal quality - a system of colors that characterize the structure of the complex of personalities in the world; methods of observation, caution, a systematic analysis of the results.

When solving competency-oriented tasks, students are able to use and notice the general in the private, to reveal the significance of established facts and patterns, to form and develop the basic mental operations.

The methods for solving competence-oriented tasks should not only promote the development of skills and skills that meet the program requirements, but also the development of creative cognitive activities. These include tasks that familiarize schoolchildren with non-standard methods of reasoning, but do not require the extension of the curriculum material.

The nature of the representation of competence-oriented tasks takes into account the psychological characteristics of students' perception of information. In particular, it is desirable that the conditions of the problems allow rather simple graphic or "subject" illustrations.

In conclusion, we note that competence-oriented tasks should include entertaining tasks that are diverse in terms of the story, in the formulation of questions, in the methods of solutions. It is desirable to include in the system tasks, the solution of which is divided in time and whose purpose is the development of certain skills and abilities, the consolidation of methods of reasoning, methods of solving problems, the development of spatial representations, the formation and development of mental operations, such as: analysis, synthesis, comparison, classification, etc.
A Theoretical Framework for a Dynamic Team Learning and Adaptation System
Authors: Sexe Frederick S.
Published: June 2018

This paper will discuss a model for team learning and adaptation by applying sociotechnical and cognitive systems concepts to a model previously developed by [1] to facilitate double-loop learning in teams and organizations. Organizational knowledge assets will be explained relative to team learning followed by an explanation of the sociotechnical system that the model is based upon. An overview of the team cognitive systems model will be provided as a precursor to explaining the learning and adaptation system. The team learning and adaptation model combines sociotechnical and cognitive systems elements to provide a model explaining how team learning at the tactical level can be aligned with other organizational resources while aligning these efforts towards organizational strategy. The proposed model also provides a holistic means for implementing a problem-solving methodology within the sociotechnical and cognitive systems contexts.

The aim of this paper is to aid practitioners seeking to improve how his or her team learns, collaborates, and innovates at all levels of the organization. The paper is geared mainly towards practitioners interested in improving his or her team's performance. Academics interested in team learning and knowledge sharing may also find the model of interest in academic pursuits related to team learning and adaptation. Practitioners can use this model to identify shortcomings in team learning and adaptation performance relative to specific work requirements. Academicians can use the model to explain sociotechnical and environmental interactions relative to how teams perform learning and adapting behaviors.
Deslocativización y abstracción diacrónica de frases preposicionales con a. Efecto dominó en un cambio léxico-semántico
Authors: Flores Dávila Rodrigo
Published: June 2018

En este artículo se analiza, desde una perspectiva diacrónica, la relación entre dos procesos de cambio léxico-semántico experimentados por frases con la pauta a +frase nominal: deslocativización y abstracción. El principal hallazgo de esta investigación es que, a lo largo de la historia, el signi- ficado básico locativo de esta clase de frases disminuyó en beneficio del no locativo; este hecho propició el incremento de frases nominales con carácter abstracto, en perjuicio de las frases nominales con carácter concreto. El interés de estos cambios léxico-semánticos radica en que se cumplieron a modo de “efecto dominó” una primera deslocativización y una subsecuente abstracción.
La descripción de las partes de la oración en las artes del cachiquel. Métodos y fuentes.
Authors: García Aranda María de los Ángeles
Published: June 2018

Este artículo tiene como propósito mostrar y analizar las descripciones de las partes de la oración (nombre, pronombre y partes indeclina- bles de la oración) que se realizaron sobre el cachiquel en la época colonial (1523-1821) gracias a los textos de Domingo Basseta, Francisco de la Parra, Benito de Villacañas, Francisco Ximénez, Carlos José Rosales, José Ildefonso Flores y Esteban Torresano, así como presentar y examinar el entorno en que fueron compuestas y las fuentes que las inspiraron, con el fin de contribuir a la lingüística misionera, sus circunstancias, sus métodos y sus tradiciones.
Ars memorativa, abejas y miel en La Celestina
Authors: Vázquez Cruz Adam Alberto
Published: June 2018

En este artículo se analiza el texto celestinesco desde la perspectiva del arte de la memoria. Gracias a la caracterización de la alcahueta como abeja y de los amantes como flores, se abre una posibilidad interpretativa que echa mano de una analogía ampliamente usada para describir los pro- cesos intelectivos. Ésta descansa en una comparación entre los procesos para elaborar miel y para generar discurso. Celestina, por medio de la palabra, manipulará a los personajes, pero su falta de prudencia la llevará a la muerte. Este artículo pretende ampliar nuestro entendimiento de La Celestina al explorar una de las tradiciones que evoca.
Institvt d´Estvdis Catalans, Diccionari Descriptiu de la Llengua Catalana, disponible en http://dcc.iec.cat/ddlc/index.asp
Authors: Battaner Arias María Paz
Published: June 2018

La total puesta a punto en consulta pública del Diccionari descriptiu de la llengua catalana (DDLC) del Institut d’Estudis Catalans a finales de 2016 representa una novedad digna de señalarse en la lexicografía de las lenguas occidentales y, muy en concreto, en las lenguas románicas...
Danaé Torres de la Rosa, Avatares editoriales de un “género”: tres décadas de la novela de la Revolución mexicana. Bonilla Artigas-Instituto Tecnológico Autónomo de México, 2015; 352 pp. (Pública-Ensayo, 7).
Authors: Arranz Conrado J.
Published: June 2018

En 1933, cuando el modelo literario de la “novela de la Revolución mexicana” comenzaba a generalizarse, de tal forma que muchos autores probaban suerte dentro de él, José Vasconcelos publicó La sonata mágica...
Yanna Hadatty Mora, Prensa y literatura para la Revolución. La Novela Semanal de “El Universal Ilustrado” (1922-1925). Universidad Nacional Autónoma de México-Ediciones de El Universal, México, 2016; 268 pp.
Authors: López Durand Mariana
Published: June 2018

La Novela Semanal es una colección fundada por Carlos Noriega Hope que de 1922 a 1925 se incluía, sin costo adicional, junto con El Universal Ilustrado, el semanario del periódico El Universal...
Dawkins’ Unrebuttable Refutation
Authors: HANKOVSZKY Tamás
Published: June 2018

In the whole fourth chapter of The God Delusion Richard Dawkins in a long and complicated argumentation attempts to prove that God’s existence is improbable and we have no reason to believe in Him. In my paper I am going to examine the basic structure of his train of thought first so that I present the detailed reconstruction of the single steps later on. Having scrutinized the reconstructed reasoning in the last section I am going to show that his main argument for atheism is unsuccessful.
Strength Characteristics of Concrete with Indian Mettakaolin and Rice Husk Ash
Authors: Swaminathen A.N. , Ravi S.Robert
Published: June 2018

Â Concrete is the most extensively used construction material around the world and its properties have been undergoing changes through technological advancements. Varieties of concrete have been developed to enhance the different properties of concrete. An investigation in to the potential use of partial replacement of mineral admixture in high performance concrete (HPC) has carried out. The engineering properties of fresh and hardenedconcrete are obtained by conducting test on slump, vee-bee, compaction factor and compressive strength, flexural strength, spilt tensile strength and modulus of elasticity, in this project partial replacement of cement bymetakaolin and rice husk ash been used for varying replacement of 0+0%, 5+105, 7.5+10%,10+10%,5+12.5%, 10+12.5%, 5+15%, 7.5+15%,Â  and 10+15%for high strength, workability and also an eco-friendly by less emission of co2. It has been concluded that strength development of concrete blended with metakaolin and rice hush ash was enhanced. It was found that in 7.5% replacement of metakaolin and 12.5% replacement of rice husk ash appear to be the optimum replacement which exhibited more strength. This investigation has proved that the MK and RHA concrete can be used as structural concrete at suitable replacement percentage.Â
Evaluation of self-injurious behavior, thermal sensitivity, food intake, fecal output, and pica after injection of three buprenorphine formulations in rats (Rattus norvegicus)
Authors: Allen Molly , Johnson Rebecca A.
Published: June 2018

OBJECTIVE To assess effects of buprenorphine hydrochloride (BH), sustained-release buprenorphine (SRB), and high-concentration buprenorphine (HCB) formulations in healthy rats.

ANIMALS 8 Sprague-Dawley rats.

PROCEDURES In a crossover-design study, rats received BH (0.05 mg/kg), SRB (1.2 mg/kg), HCB (0.30 mg/kg), or 5% dextrose solution (0.2 mL/kg), SC, once. Self-injurious behavior and thermal sensitivity (hind limb withdrawal latencies) were assessed prior to injection (time 0) and 1, 4, 8, 12, and 24 hours after injection. Food intake, kaolin intake, and fecal output were measured over 12-hour light and dark periods before and after each treatment. Values were compared among treatments and time points.

RESULTS Self-injurious behavior was detected with all buprenorphine treatments; scores were greater at all time points during the 12 hours after HCB and 24 hours after SRB administration than at time 0. Percentage change in hind limb withdrawal latencies from time 0 was higher with BH and HCB 1 hour after injection than at other time points. Postinjection light-period food intake was higher (BH and HCB) and dark-period food intake was lower (BH, HCB, and SRB), compared with preinjection values for the same treatments. For SRB, postinjection light-period kaolin intake was greater than the preinjection value, and postinjection light- and dark-period kaolin intake was greater than that for other treatments.

CONCLUSIONS AND CLINICAL RELEVANCE Hypoalgesic effects were briefly observed after administration of BH or HCB in healthy rats; adverse effects were detected in some rats with all buprenorphine formulations. Studies comparing effects of BH, SRB, and HCB in rats undergoing surgery or other noxious stimuli are indicated to determine clinical benefits in this species.
Effects of a nutrient-enriched water on water intake and indices of hydration in healthy domestic cats fed a dry kibble diet
Authors: Zanghi Brian M. , Gerheart Lynn , Gardner Cari L.
Published: June 2018

OBJECTIVE To evaluate the effects of drinking nutrient-enriched water (NW) on water intake and indices of hydration in healthy domestic cats fed a dry kibble diet ad libitum.

ANIMALS 18 domestic shorthair cats.

PROCEDURES Group-housed cats were assigned to tap water (TW; n = 9) or NW (9) groups. All cats received TW at baseline (days −7 to −1). No changes were made to the food-water regimen for the TW group. The NW group received NW instead of TW from days 0 through 10, then received TW and NW in separate bowls (days 11 through 56). Food intake was measured through day 10; liquid consumed by drinking was measured throughout the study. Blood and urine samples were collected at predetermined times for analyses; 48-hour urine collection (days 28 through 30 or 31 through 33) was performed to assess output volume and aid endogenous creatinine-based glomerular filtration rate (GFR) determination. Data were analyzed with linear mixed-effects models.

RESULTS Baseline TW and calorie intake were similar between groups. The NW treatment was significantly associated with increased liquid consumption during the treatment phase. Mean urine output was significantly higher in the NW group (15.2 mL/kg/d) than in the TW group (10.3 mL/kg/d). Mean GFR (1.75 vs 1.87 mL/min/kg, respectively) did not differ between groups. Effects of treatment and time were each significant for urine specific gravity and osmolality and urine creatinine, phosphate, and urea nitrogen concentrations, with lower values for the NW group.

CONCLUSIONS AND CLINICAL RELEVANCE Results suggested that consumption of the NW can increase liquid intake and improve measures of hydration in healthy cats. These effects may offer health benefits to some cats in need of greater water consumption.
Evaluation of a fluorescence resonance energy transfer quantitative polymerase chain reaction assay for identification of gyrA mutations conferring enrofloxacin resistance in canine urinary Escherichia coli isolates and canine urine specimens
Authors: Behringer Megan G. , Boothe Dawn M. , Thungrat Kamoltip
Published: June 2018

OBJECTIVE To evaluate a fluorescence resonance energy transfer quantitative PCR (FRET-qPCR) assay for detection of gyrA mutations conferring fluoroquinolone resistance in canine urinary Escherichia coli isolates and canine urine specimens.

SAMPLE 264 canine urinary E coli isolates and 283 clinical canine urine specimens.

PROCEDURES The E coli isolates were used to validate the FRET-qPCR assay. Urine specimens were evaluated by bacterial culture and identification, isolate enrofloxacin susceptibility testing, and FRET-qPCR assay. Sensitivity and specificity of the FRET-qPCR assay for detection of gyrA mutations in urine specimens and in E coli isolated from urine specimens were computed, with results of enrofloxacin susceptibility testing used as the reference standard.

RESULTS The validated FRET-qPCR assay discriminated between enrofloxacin-resistant and enrofloxacin-susceptible E coli isolates with an area under the receiver operating characteristic curve of 0.92. The assay accurately identified 25 of 40 urine specimens as containing enrofloxacin-resistant isolates (sensitivity, 62.5%) and 226 of 243 urine specimens as containing enrofloxacin-susceptible isolates (specificity, 93.0%). When the same assay was performed on E coli isolates recovered from these specimens, sensitivity (77.8%) and specificity (94.8%) increased. Moderate agreement was achieved between results of the FRET-qPCR assay and enrofloxacin susceptibility testing for E coli isolates recovered from urine specimens.

CONCLUSIONS AND CLINICAL RELEVANCE The FRET-qPCR assay was able to rapidly distinguish between enrofloxacin-resistant and enrofloxacin-susceptible E coli in canine clinical urine specimens through detection of gyrA mutations. Therefore, the assay may be useful in clinical settings to screen such specimens for enrofloxacin-resistant E coli to avoid inappropriate use of enrofloxacin and contributing to antimicrobial resistance.
Amount of skin shrinkage affecting tumor versus grossly normal marginal skin of dogs for cutaneous mast cell tumors excised with curative intent
Authors: Upchurch David A. , Klocke Emily E. , Henningson Jamie N.
Published: June 2018

OBJECTIVE To assess differences in skin shrinkage between grossly visible tumor and grossly normal marginal skin of dogs for cutaneous mast cell tumors (MCTs) excised with curative intent and to determine an equation to estimate postexcisional gross tumor margins from preexcisional measurements and vice versa.

SAMPLE 19 cytologically confirmed and surgically excised cutaneous MCTs obtained from dogs.

PROCEDURES Tumors were measured in craniocaudal and dorsoventral directions before excision, immediately after excision, and after fixation in formalin. Both grossly visible tumor and surrounding grossly normal skin that comprised the surgical margin were measured at each time point. Percentage of shrinkage was compared among time points and between the tumor and surrounding grossly normal skin. Patient and histopathologic variables were correlated to skin shrinkage.

RESULTS Overall shrinkage was 17.70%. The amount of shrinkage within the grossly visible tumor (4.45%) was less than that within the surrounding grossly normal skin (24.42%). Most of the shrinkage occurred immediately after excision. There was no effect of age, sex, completeness of excision, or degree of edema. Accuracy of an equation to estimate postexcisional margins from preexcisional measurements was only 18.4%.

CONCLUSIONS AND CLINICAL RELEVANCE Grossly evident MCTs of dogs shrunk less than did the grossly normal surrounding skin. Although an equation to estimate postexcisional margins from preexcisional measurements could be derived, it likely would need to contain additional variables not included in the study reported here. Until such an equation exists, care must be used when extrapolating surgical margins from histologic margins and vice versa.
Antalya İli Tarıma Dayalı Sanayinin Yapısal Analizi
Authors: Karkacier Osman
Published: June 2018

Bu çalışmada Antalya ili tarıma dayalı sanayi sektörünün Input-Output Analizi ile yapısal ilişkileri incelemiştir. Bu amaçla Antalya ilinde faaliyet gösteren tarıma dayalı sanayi işletmeleri ile anket yapılmıştır. Anketlerden elde edilen veriler yardımıyla endüstriyel işlemler tablosu oluşturulmuştur. Bu tablo üzerinden input-output katsayılar matrisine ulaşılmış ve leontief matrisi işlemleri ile sektörler üzerinde üretim çoğaltanları hesaplanmıştır. Çalışmada tarıma dayalı sanayi sektörleri toplulaştırılarak 9 sektöre indirgenmiştir. Elde edilen sonuçlara göre üretim çoğaltanları açısından en yüksek katkıyı sağlayan sektör bitkisel üretimdir. Bu sektörün Leontief Ters Matrisi sütun toplamları 3,26904 olup bu şu anlama gelmektedir; bitkisel üretim sektöründe 1 birimlik bir üretim artışına karşılık diğer dokuz sektörde yaratacağı üretim artışı 3,26904 kat olacaktır. Bu sektörü 3,07305 katsayı bitkisel yağlar ve 2,736016 ile de ile meyve-sebze işleme sanayi izlemektedir. Şekerli ürünler sanayi alanında 1,767583 katsayı hesaplanmıştır. Bu katsayılarla bu alt sektörlerin önemli katkılar sağladığı söylenebilir. İncelenen sektörlerin tümünde birde üretimin bir birim artırılması halinde ilgili satırdaki sektörün üretiminde ortaya çıkacak üretim artışını veren bir başka çoğaltanda söz konusudur. Buna göre unlu mamuller sektörü katsayısı 2,660875 olup en yüksektir. Bu rakama göre incelenen diğer sekiz sektörün üretimlerini bir birim artırmaları halinde unlu mamuller sanayi sekiz sektöre verdiği girdi düzeyini 2,66 kat artırmak durumunda kalacağı söylenebilir.
The Investigation of Antidiabetic Effects of Leontice leontopetalum Extract on Human Pancreatic β Cell Lines (1.1B4) Treated with Streptozotocin
Authors: Güven Celal , Taşkın Eylem , Yumrutaş Önder , Türker Şener Leyla , Dal Fulya , Ahbab Mufide , Bozgeyik İbrahim , Albeniz Işıl , Bağış Haydar , Pehlivan Mustafa , Üçkardeşler Fatih , Akçakaya Handan
Published: June 2018

One of the alternative therapeutic methods is herbal medicine. Leontice leontopetalum belongs to Berberidaceae family. The aim of study was investigated the extract of LL on human pancreatic beta cell-treated with STZ. Materials and methods: The human pancreatic beta cell (1.1B4) line was used the current study. LL‘s extracts (1, 10, 100, and 1000 ug/ml) were supplemented in media for twenty-four hours and/or after STZ treatment (10 and 20 mM). Cells survivals (MTT), cells proliferation were shown by using xCelligence. Insulin content and releasing were measured at 1.1, 8.4 and 16.7 mM glucose concentrations. Results: The result of MTT was shown that cell survival was decreased, based on dose-dependent. When looked at xCelligence results, cell proliferation in STZ groups and the lowest and highest concentrations of LL were attenuated in a dose-dependent manner. Also, cotreatments of LL and STZ were decreased as well. The result of insulin-releasing on glucose induction was shown that STZ concentration gave rise to reduce insulin content at low and high glucose levels. Also, co-treatment of LL and STZ attenuated insulin content based on dose. Conclusion: It was considered that LL treatment led to increased insulin realizing, resulting from decreasing insulin content in diabetic beta cells, but decrease cell survival.
Development of living floor spaces on the basis of ecological economic and social programs
Authors:   Research Centre ", Bryndin Evgeniy ,   NATURE INFORMATIC",   , Technological Platform Future Medicine, Novosibirsk, Russia
Published: June 2018

The mankind the activity moves to an ecological disaster. The technocratic approach to the organization of activity breaking environment ecology forces to defend the Nature accidents. The mankind crossed line of technological development when the Planet became vulnerable. Will help to rescue mankind from an ecological disaster, ecological thinking and behavior of people, and their ecological responsibility, the moral relation to the nature; harmonization of vital system by waste-free industrial cycles of the combined productions; eco-world formation. The problem of global ecological stabilization can be solved by implementation of social and economic interdisciplinary programs, such as, first, the ecological program “Clean Air, Clear Water, Pure Food, Net Energy, Pure Cities and Villages, Pure Nature”, secondly, the program of development ecological and health the preserving with the filled economy resources, thirdly, the “Development Health of the Preserving Medicine and Health System” program, fourthly, the program of the ecological focused interdisciplinary education, fifthly, the program of peaceful, humane environmental policy, sixthly, the program of civil education of harmonious life for a sustainable development, seventhly, the program of formation of fair democracy as way of life of society. Social and economic programs for stabilization of ecology need to be realized under the competent direction and control of the institutionalized infrastructure of scientific and educational society and on the basis of ecological thinking and behavior of all segments ofthe population. World community will have to undertake decisive measures to stabilize the environmental ecological processes in order to keep modern and future generations supplied with a harmony between the meeting of their reasonable needs, social and economic problems decision, with the life on the Earth being preserved.
EL PAISAJE AGRÍCOLA COMO PATRIMONIO CULTURAL: BASES LEGALES PARA UN ANÁLSIS CRÍTICO
Authors: Moreno-Trujillo Eulalia
Published: June 2018

Desde finales del S.XX se introduce del paisaje como elemento del patrimonio cultural, como expresión de la interacción hombre-naturaleza, y una de las manifestaciones más antiguas y trascendentes de esa interacción es la agricultura. Se analiza el concepto de paisaje agrícola como paisaje cultural y su regulación legal, desde un punto de vista crítico, destacando sus carencias y dificultades, tanto como elemento natural, etnográfico y mixto y marcando las líneas de injerencia con el régimen jurídico general de la propiedad privada.
PROFILE OF ORGANIC ACIDS AND BIOACTIVE COMPOUNDS IN THE SENSORY QUALITY DISCRIMINATION OF ARABICA COFFEE
Authors: Ribeiro Diego Egídio , Borém Flávio Meira , Nunes Cleiton Antônio , Alves Ana Paula De Carvalho , Dos Santos Claudia Mendes , Taveira José Henrique Da Silva , Dias Laryanne Lopes de Carvalho
Published: June 2018

O presente estudo foi desenvolvido para investigar o potencial dos ácidos orgânicos e bioativos presentes no grão cru para discriminar a qualidade sensorial do café proveniente de diferentes genótipos e métodos de processamento. Durante as safras 2010, 2011 e 2012, foram analisadas a qualidade da bebida do café e o perfil de ácidos orgânicos e dos bioativos, cafeína, trigonelina e ácidos clorogênicos (3,4 e 5-CQA) do grão cru de amostras representativas dos genótipos Bourbon Amarelo e Acaiá. As amostras foram coletadas em lavouras comerciais com altitudes variando entre 932 a 1391 m, no município de Carmo de Minas, MG, Brasil. Os métodos de processamento adotados foram: via seca (café natural) e via úmida com descascamento e desmucilamento mecânico do fruto. Todos os procedimentos de colheita e pós-colheita foram realizados conforme as principais tecnologias para produção de cafés especiais. A análise sensorial foi realizada utilizando-se a metodologia proposta pela Associação Americana de Cafés Especiais (SCAA). As análises químicas foram realizadas por HPLC. Os dados foram investigados aplicando-se a Análise de Componentes Principais (ACP). As variações nos teores de ácidos orgânicos e dos bioativos analisados ocorreram em razão do método de processamento do café. Para os genótipos Bourbon Amarelo e Acaiá, as diferenças existentes no perfil de ácidos orgânicos associado com os bioativos, cafeína, trigonelina e ácidos clorogênicos (3,4 e 5-CQA) foram determinantes para discriminar a qualidade do café descascado e desmucilado mecanicamente.