bluuebunny/crossref_metadata_2025 huggingface dataset:
The Study on the Effectiveness of Sustainable Customer Relationship Management: Evidence from the Online Shopping Industry
Authors: Li Jiling , Lin Zekai , Zhang Xiaheng
Published: March 2023

Sustainable development integrates business, environmental, and social objectives into a unified effort to achieve a common goal. Sustainable customer relationship management (CRM) combines company strategy, customer-focused business processes, and computer technologies. From the consumer’s perspective, it lowers psychological, energy, time, and other costs; from the company’s perspective, it offers a means of engaging with customers to build lasting and reliable relationships. The sustainable CRM program provides advantages to businesses in various industries, particularly online commerce. It alludes to a comprehensive strategy that promotes solid interactions between buyers and sellers of goods and services. Since current customer retention is less costly than new customer attraction in competitive markets, especially online shopping, identifying the factors affecting relationship management with stable customers is essential. This investigation intends to evaluate the effect of the use of management information systems (MIS), as well as insights on employee behavior and knowledge, and customer behavior (satisfaction and loyalty), on the effectiveness of sustainable CRM in online shopping. The model is validated using the PLS–SEM technique, and study sample of 293 employees and managers from private organizations. According to the results, the MIS, employee behavior and knowledge, customer satisfaction, and customer loyalty influence the effectiveness of sustainable CRM in online shopping. Furthermore, employee behavior and knowledge positively moderate the relationship between customer loyalty and the effectiveness of sustainable CRM. However, the moderating role of employee behavior and knowledge on customer satisfaction and the effectiveness of sustainable CRM is not confirmed. Overall, taking these characteristics into account might help organizations to take significant steps toward increasing the efficacy of sustainable CRM.
Enhancing Local Decisions in Agent-Based Cartesian Genetic Programming by CMA-ES
Authors: Bremer Jörg , Lehnhoff Sebastian
Published: March 2023

Cartesian genetic programming is a popular version of classical genetic programming, and it has now demonstrated a very good performance in solving various use cases. Originally, programs evolved by using a centralized optimization approach. Recently, an algorithmic level decomposition of program evolution has been introduced that can be solved by a multi-agent system in a fully distributed manner. A heuristic for distributed combinatorial problem-solving was adapted to evolve these programs. The applicability of the approach and the effectiveness of the used multi-agent protocol as well as of the evolved genetic programs for the case of full enumeration in local agent decisions has already been successfully demonstrated. Symbolic regression, n-parity, and classification problems were used for this purpose. As is typical of decentralized systems, agents have to solve local sub-problems for decision-making and for determining the best local contribution to solving program evolution. So far, only a full enumeration of the solution candidates has been used, which is not sufficient for larger problem sizes. We extend this approach by using CMA-ES as an algorithm for local decisions. The superior performance of CMA-ES is demonstrated using Koza’s computational effort statistic when compared with the original approach. In addition, the distributed modality of the local optimization is scrutinized by a fitness landscape analysis.
A Novel Approach to Service Design within the Tourism Industry: Creating a Travel Package with AHP-TRIZ Integration
Authors: Ruano Marvin , Huang Chien-Yi
Published: March 2023

Creating a suitable travel package has become increasingly difficult for businesses within the tourism industry because of various factors affecting tourists’ decision-making behavior and businesses’ desire to make profits. This paper proposes a novel approach to service design within the tourism industry by integrating the analytic hierarchy process (AHP) and the theory of inventive problem solving (TRIZ) to design a suitable travel package while taking into account both consumer and business perspectives. Through a case study application, we identify the most important consumer and business factors with AHP and the Delphi method and then solve the existing contradiction with TRIZ. We collect both qualitative and quantitative data from experts and visitors through a survey approach consisting of 56 fully completed responses for a target of only 35 responses as required by AHP. We analyze these data using Super Decisions software to obtain the necessary results. AHP helps weigh and rank the 4 criteria and 16 sub-criteria, whereas TRIZ provides recommendations to resolve the contradiction, based on the 40 inventive principles, to create a cost-effective travel package to Belize in Central America. The main contradiction was feasibility versus cost, and the most applicable corresponding principles were dynamization, self-service, local quality, and prior action. Overall, this paper gives vital insights into the tourism sector to anyone interested in this topic and provides a precise AHP-TRIZ application framework with clear procedures. The results and methodologies could also help scholars and academics with future AHP-TRIZ applications in other research fields or possible expansions of this new approach.
The Application of Reference Dose Prediction Model to Human Health Water Quality Criteria and Risk Assessment
Authors: Men Shu-Hui , Xie Xin , Zhao Xin , Zhou Quan , Chen Jing-Yi , Jiao Cong-Ying , Yan Zhen-Guang
Published: March 2023

Oral reference dose (RfD) is a key parameter for deriving the human health ambient water quality criteria (AWQC) for non-carcinogenic substances. In this study, a non-experimental approach was used to calculate the RfD values, which explore the potential correlation between toxicity and physicochemical characteristics and the chemical structure of pesticides. The molecular descriptors of contaminants were calculated using T.E.S.T software from EPA, and a prediction model was developed using a stepwise multiple linear regression (MLR) approaches. Approximately 95% and 85% of the data points differ by less than 10-fold and 5-fold between predicted values and true values, respectively, which improves the efficiency of RfD calculation. The model prediction values have certain reference values in the absence of experimental data, which is beneficial to the advancement of contaminant health risk assessment. In addition, using the prediction model constructed in this manuscript, the RfD values of two pesticide substances in the list of priority pollutants are calculated to derive human health water quality criteria. Furthermore, an initial assessment of the health risk was performed by the quotient value method based on the human health water quality criteria calculated by the prediction model.
Feasibility and Acceptability of a Strategy Deploying Multiple First-Line Artemisinin-Based Combination Therapies for Uncomplicated Malaria in the Health District of Kaya, Burkina Faso
Authors: Kaboré Jean Moïse Tanga , Siribié Mohamadou , Hien Denise , Soulama Issiaka , Barry Nouhoun , Baguiya Adama , Tiono Alfred B. , Burri Christian , Tchouatieu André-Marie , Sirima Sodiomon B.
Published: March 2023

(1) Background: Effective malaria case management relies on World Health Organization (WHO) recommended artemisinin-based combination therapies (ACTs), but partial resistance to artemisinin has emerged and is spreading, threatening malaria control and elimination efforts. The strategy of deploying multiple first-line therapies (MFT) may help mitigate this threat and extend the therapeutic life of current ACTs. (2) Methods: A district-wide pilot quasi-experimental study was conducted, deploying three different ACTs at the public health facility (PHF) level for uncomplicated malaria treatment from December 2019 to December 2020 in the health district (HD) of Kaya, Burkina Faso. Mixed methods, including household and health facility-based quantitative and qualitative surveys, were used to evaluate the pilot programme. (3) Results: A total of 2008 suspected malaria patients were surveyed at PHFs, of which 79.1% were tested by rapid diagnostic test (RDT) with 65.5% positivity rate. In total, 86.1% of the confirmed cases received the appropriate ACT according to the MFT strategy. The adherence level did not differ by study segment (p = 0.19). Overall, the compliance level of health workers (HWs) with MFT strategy was 72.7% (95% CI: 69.7–75.5). The odds of using PHF as the first source of care increased after the intervention (aOR = 1.6; 95% CI, 1.3–1.9), and the reported adherence to the 3-day treatment regimen was 82.1%; (95% CI: 79.6–84.3). Qualitative results showed a high acceptance of the MFT strategy with positive opinions from all stakeholders. (4) Conclusions: Implementing an MFT strategy is operationally feasible and acceptable by stakeholders in the health systems in Burkina Faso. This study provides evidence to support the simultaneous use of multiple first-line artemisinin combination therapies in malaria-endemic countries such as Burkina Faso.
Dichotomous Keys Based on Cytogenetic Data for Triatomines Reported in Brazilian Regions with Outbreaks of Orally Transmitted Chagas Disease (Pernambuco and Rio Grande Do Norte)
Authors: de Mello Denis Vinícius , Nhapulo Emercio Felisberto , Cesaretto Laura Poloto , Alevi Julia Junqueira , Cristal Daniel Cesaretto , Montanari Giulia , Galvão Cleber , Alevi Kaio Cesar Chaboli
Published: March 2023

Chagas disease (CD) affects about eight million people worldwide. Brazil has the highest number of estimated cases and the largest number of deaths due to CD. Considering the recent outbreaks of oral CD involving at least 27 cases of acute CD in Pernambuco (PE) as well as 18 cases and 2 deaths in the Rio Grande do Norte (RN), we developed dichotomous keys for the identification of triatomine species in these Brazilian states based on cytogenetic data. All triatomine species could be distinguished by cytogenetic characteristics, emphasizing the importance of the newly developed taxonomic keys for the correct identification of triatomes from PE and RN, particularly for species that exhibit morphological similarities, such as Triatoma brasilensis and T. petrocchiae (present in both states) and T. maculata and T. pseudomaculata (as T. pseudomaculata has been misidentified as T. maculata in PE and RN). These alternative keys are expected to provide a useful tool for the scientific community and, above all, health agents, aimed at preventing mistakes from occurring in the identification of the vectors present in PE and RN related to CD outbreaks caused by oral infection.
Modeling the Climatic Suitability of COVID-19 Cases in Brazil
Authors: Neves Jéssica Milena Moura , Belo Vinicius Silva , Catita Cristina Maria Souza , de Oliveira Beatriz Fátima Alves , Horta Marco Aurelio Pereira
Published: March 2023

Studies have shown that climate may affect the distribution of coronavirus disease (COVID-19) and its incidence and fatality rates. Here, we applied an ensemble niche modeling approach to project the climatic suitability of COVID-19 cases in Brazil. We estimated the cumulative incidence, mortality rate, and fatality rate of COVID-19 between 2020 and 2021. Seven statistical algorithms (MAXENT, MARS, RF, FDA, CTA, GAM, and GLM) were selected to model the climate suitability for COVID-19 cases from diverse climate data, including temperature, precipitation, and humidity. The annual temperature range and precipitation seasonality showed a relatively high contribution to the models, partially explaining the distribution of COVID-19 cases in Brazil based on the climatic suitability of the territory. We observed a high probability of climatic suitability for high incidence in the North and South regions and a high probability of mortality and fatality rates in the Midwest and Southeast regions. Despite the social, viral, and human aspects regulating COVID-19 cases and death distribution, we suggest that climate may play an important role as a co-factor in the spread of cases. In Brazil, there are regions with a high probability that climatic suitability will contribute to the high incidence and fatality rates of COVID-19 in 2020 and 2021.
SARS-CoV-2 ORF8: A Rapidly Evolving Immune and Viral Modulator in COVID-19
Authors: Arduini Ariana , Laprise Frederique , Liang Chen
Published: March 2023

The COVID-19 pandemic has resulted in upwards of 6.8 million deaths over the past three years, and the frequent emergence of variants continues to strain global health. Although vaccines have greatly helped mitigate disease severity, SARS-CoV-2 is likely to remain endemic, making it critical to understand its viral mechanisms contributing to pathogenesis and discover new antiviral therapeutics. To efficiently infect, this virus uses a diverse set of strategies to evade host immunity, accounting for its high pathogenicity and rapid spread throughout the COVID-19 pandemic. Behind some of these critical host evasion strategies is the accessory protein Open Reading Frame 8 (ORF8), which has gained recognition in SARS-CoV-2 pathogenesis due to its hypervariability, secretory property, and unique structure. This review discusses the current knowledge on SARS-CoV-2 ORF8 and proposes actualized functional models describing its pivotal roles in both viral replication and immune evasion. A better understanding of ORF8’s interactions with host and viral factors is expected to reveal essential pathogenic strategies utilized by SARS-CoV-2 and inspire the development of novel therapeutics to improve COVID-19 disease outcomes.
Formative Research on HPV Vaccine Acceptance among Health Workers, Teachers, Parents, and Social Influencers in Uzbekistan
Authors: Warsi Sahil Khan , Nielsen Siff Malue , Franklin Barbara A. K. , Abdullaev Shukhrat , Ruzmetova Dilfuza , Raimjanov Ravshan , Nagiyeva Khalida , Safaeva Kamola
Published: March 2023

Human papillomavirus (HPV) vaccines effectively prevent cervical cancer, most of which results from undetected long-term HPV infection. HPV vaccine introduction is particularly sensitive and complicated given widespread misinformation and vaccination of young girls before their sexual debut. Research has examined HPV vaccine introduction in lower- and middle-income countries (LMICs), but almost no studies attend to HPV vaccine attitudes in central Asian countries. This article describes the results of a qualitative formative research study to develop an HPV vaccine introduction communication plan in Uzbekistan. Data collection and analysis were designed using the Capability, Opportunity, and Motivation for Behaviour change (COM-B) mode for understanding health behaviours. This research was carried out with health workers, parents, grandparents, teachers, and other social influencers in urban, semi-urban, and rural sites. Information was collected using focus group discussions (FGDs) and semi-structured in-depth interviews (IDIs), and data in the form of participants’ words, statements, and ideas were thematically analysed to identify COM-B barriers and drivers for each target group’s HPV vaccine-related behaviour. Represented through exemplary quotations, findings were used to inform the development of the HPV vaccine introduction communication plan. Capability findings indicated that participants understood cervical cancer was a national health issue, but HPV and HPV vaccine knowledge was limited among non-health professionals, some nurses, and rural health workers. Results on an opportunity for accepting the HPV vaccine showed most participants would do so if they had access to credible information on vaccine safety and evidence. Regarding motivation, all participant groups voiced concern about the potential effects on young girls’ future fertility. Echoing global research, the study results highlighted that trust in health workers and the government as health-related information sources and collaboration among schools, municipalities, and polyclinics could support potential vaccine acceptance and uptake. Resource constraints precluded including vaccine target-aged girls in research and additional field sites. Participants represented diverse social and economic backgrounds reflective of the country context, and the communication plan developed using research insights contributed to the Ministry of Health (MoH) of the Republic of Uzbekistan HPV vaccine introduction efforts that saw high first dose uptake.
Transcriptomic Changes and satP Gene Function Analysis in Pasteurella multocida with Different Levels of Resistance to Enrofloxacin
Authors: Li Xue-Song , Qi Yu , Xue Jun-Ze , Xu Guan-Yi , Xu Yu-Xuan , Li Xuan-Yu , Muhammad Inam , Kong Ling-Cong , Ma Hong-Xia
Published: March 2023

Pasteurella multocida (Pm) is one of the major pathogens of bovine respiratory disease (BRD), which can develop drug resistance to many of the commonly used antibiotics. Our earlier research group found that with clinical use of enrofloxacin, Pm was more likely to develop drug resistance to enrofloxacin. In order to better understand the resistance mechanism of Pm to enrofloxacin, we isolated PmS and PmR strains with the same PFGE typing in vitro, and artificially induced PmR to obtain the highly resistant phenotype, PmHR. Then transcriptome sequencing of clinically isolated sensitive strains, resistant and highly drug-resistant strains, treated with enrofloxacin at sub-inhibitory concentrations, were performed. The satP gene, of which the expression changed significantly with the increase in drug resistance, was screened. In order to further confirm the function of this gene, we constructed a satP deletion (ΔPm) strain using suicide vector plasmid pRE112, and constructed the C-Pm strain using pBBR1-MCS, and further analyzed the function of the satP gene. Through a continuously induced resistance test, it was found that the resistance rate of ΔPm was obviously lower than that of Pm in vitro. MDK99, agar diffusion and mutation frequency experiments showed significantly lower tolerance of ΔPm than the wild-type strains. The pathogenicity of ΔPm and Pm was measured by an acute pathogenicity test in mice, and it was found that the pathogenicity of ΔPm was reduced by about 400 times. Therefore, this study found that the satP gene was related to the tolerance and pathogenicity of Pm, and may be used as a target of enrofloxacin synergistic effect.
Effects of New Mutations in BMPRIB, GDF9, BMP15, LEPR, and B4GALNT2 Genes on Litter Size in Sheep
Authors: Ji Xuewen , Cao Ziwei , Hao Qi , He Mei , Cang Ming , Yu Haiquan , Ma Qing , Li Xihe , Bao Siqin , Wang Jianguo , Tong Bin
Published: March 2023

Prolificacy is a crucial characteristic of livestock, particularly for species such as sheep that have many births. The objectives of this study were as follows: (1) to investigate the genetic diversity of the 13 new and 7 known variants in the BMPRIB, GDF9, BMP15, LEPR, and B4GALNT2 genes in Ujimqin (UM), the F1 population of Dorper × Ujimqin crossbred (DPU), the F1 population of Suffolk × Ujimqin crossbred (SFKU), Sonid sheep (SN), Tan sheep (Tan), Hu sheep (Hu), and Small-tailed Han sheep (STH) sheep breeds/populations; (2) to perform an association analysis of the above 20 variants with litter size in 325 UM, 304 DPU, and 66 SFKU sheep populations; (3) to compare the frequencies of the litter-size-related alleles of these 20 variants among 8 sheep breeds/populations (the above seven sheep breeds + Mongolia sheep breed). With the use of the Sequenom MassARRAY®SNP assay technology, these 20 mutations were genotyped. The association analysis results showed that the c.746A>G (FecB) mutation in BMPR1B was significantly associated with the litter size of UM and DPU, the c.994A>G (FecGA) in GDF9 was significantly associated with the litter size of SFKU, and the c.31_33CTTinsdel (B1) in BMP15 was significantly associated with the litter size of UM. Our findings might provide valuable genetic markers for expanding sheep litter sizes.
Heavy Metals in Sediments of Hulun Lake in Inner Mongolia: Spatial-Temporal Distributions, Contamination Assessment and Source Apportionment
Authors: Liu Tong , Zhang Dasheng , Yue Weifeng , Wang Boxin , Huo Litao , Liu Kuo , Zhang Bo-Tao
Published: March 2023

The spatial and temporal distributions, contamination evaluation, and source apportionment of Cu, Zn, As, Pb, Cd, and Cr in the sediments of Hulun Lake were explored in this work. The pollution characteristics of six heavy metals were assessed by single factor pollution index (PI) and geo-accumulation index (Igeo). The sources of heavy metals in the surface sediments were analyzed by the positive definite matrix factorization (PMF) and Pearson correlation analysis. The sedimentary records of heavy metals in core sediments were reproduced by radioisotopes. The average concentrations of 6 heavy metals except Cd were lower than the corresponding background values. The spatial distributions of Cu, Zn, Cr, Cd and As were generally similar and showed higher abundances in the southwestern part of the lake. With the use and import of heavy metals, the concentration of heavy metals in core sediments increased with the fluctuation of years. The peak of heavy metal concentration was related to the high growth rate of gross domestic product in 2003-2008. The single factor pollution index and geo accumulation index results showed that the surface sediment was mainly polluted by Cd, followed by Zn and As. Natural parent material, agricultural activities and industrial activities were the main sources of heavy metal pollution in the sediments, accounting for 17.03%, 26.34%, and 56.63% of the total heavy metal accumulation, respectively. Pb was derived mainly from natural parent material. Cd and As were closely associated with agricultural activities. Cu and Zn were mainly attributed to industrial mining activities. Source apportionment of the ecological risks of heavy metals illustrated that industrial sources were the primary ecosystem risk sources (66.1%), followed by agricultural sources (23.75%) and natural sources (10.15%). The results will also provide reference data for future studies of heavy metals pollution in sediments from Hulun Lake and other lakes.
Application and Automatic Monitoring and Analysis of Hybrid Support Structure in Ultra-DEEP Foundation Pit Engineering in the Lanzhou Area under Complex Environmental Conditions
Authors: Wu Jian , Ye Shuaihua , Wang Zhiquan , Yang Dong
Published: March 2023

This paper takes the deep foundation pit project of Lanzhou Hospital of Traditional Chinese Medicine as the background. The design and construction of the foundation pit is relatively difficult due to the complex environment around the pit, the dense surrounding buildings, the complex underground soil layer and the influence of groundwater on the pit. In order to detect problems in the construction process, the pit was monitored in real time through an automated monitoring system for the whole process of excavation and backfilling of the pit. The analysis of the actual monitoring data shows that: (i) the support scheme of bored pile + prestressed anchor cable support combined with concrete corner bracing can meet the design of this type of foundation pit without causing disturbance to the surrounding buildings; (ii) combined with the actual case of the influence of groundwater on the excavation process of the foundation pit, it proves that the real-time measurement by the robot can timely detect the safety hazards caused by external factors during the construction process of the foundation pit. The project is a very important one for deep pits and complex pits. This project provides a good reference case for deep foundation pits and foundation pit projects in complex environments.
Strategy to Improve Employees Performance by Implementing a Paternalistic Leadership Style and Enhancing Intrinsic Motivation
Authors:   Department of Marketing Management, Universitas Komputer Indonesia, Indonesia, Rizaldi Arjuna
Published: March 2023

This research aims to analyze the impact of paternalistic leadership style and intrinsic motivation on the improvement of employee’s performance. The research was conducted on agriculture company with the employees as the research subject. The data used in this research were both primary in form of questionnaire as well as secondary data obtained from various scientific literature such as academic journals, textbooks, and various documents from the company. The Multiple Linear Regression was used to analyze the respondent's answer, and the hypotheses were tested using the t-test and f-test. The result shows that the employee’s performance was significantly affected by paternalistic leadership style and intrinsic motivation of the employee, both partially and simultaneously. Which means that employee’s performance will improve by implementing paternalistic leadership style and enhancing intrinsic motivation of the employee. This research is expected to have impact on the improvement of employee’s performance by implementing a paternalistic leadership style in order to enhance the intrinsic motivation of the employee.
Composite Stock Price Index during Covid-19 Pandemic at the Indonesian Stock Exchange
Authors: Ismawati Linna
Published: March 2023

COVID-19 pandemic has affected economic conditions, especially markets and industries this year. Covid-19 pandemic resulted in reduced economic growth, decreased investment in the capital market, which was marked by the weakening of the Composite Stock Price Index on the Indonesia Stock Exchange. This study aims to analyze changes in the Composite Stock Price Index in covid-19 pandemic conditions. The research method used is descriptive and verification methods with a quantitative approach. The data used are secondary data including inflation data, Dow Jones Index and Composite Stock Price Index (IHSG), research analysis through multiple regression analysis, classical assumption test, Pearson correlation analysis, coefficient of determination analysis, and hypothesis testing. The results showed that during Covid-19 Pandemic, the Composite Stock Price Index decreased significantly. The relatively high inflation rate and the decline in the Dow Jones Index during Covid-19 pandemic had an impact on the decrease in the Composite Stock Price Index on the Indonesia Stock Exchange. Inflation partially has a significant negative effect on the Composite Stock Price Index (CSPI), while the partial Dow Jones Index has a significant positive effect to the Composite Stock Price Index (CSPI). The results of this study have an impact in determining investment policies for investors and also for making the right decisions by the issuer so as not to cause a decline in stock value.
Analysis of the Effectiveness of Social Media Marketing on Fashion Product Purchasing Decisions during the Covid-19 Pandemic
Authors:   Departemen Magister Manajemen, Universitas Komputer Indonesia, Indonesia, Prasetyo Alfian Singgih , Wahdiniwaty Rahma ,   Departemen Magister Manajemen, Universitas Komputer Indonesia, Indonesia
Published: March 2023

This research aims to analyze the effectiveness of a social media marketing strategy as an effort on fashion product purchasing decisions during a pandemic. Data collection was carried out by means of a qualitative methods approach, carried out by interviews and online data collection, the subjects of this research were users of fashion products in the city of Bandung. The results of this research are expected to provide a social media marketing strategy to increase effectiveness in the form of activation and online content in an effort to make purchasing decisions fashion product in the midst of a pandemic where everyone is stay at home and spends more time with social media. A social media marketing can have an effective impact on purchasing decision making, as evidenced by the increasing activity through social media, many people who are living at home have given new habits to longer with social media, they searched many information and make purchases online post pandemic, for that industry needs to develop creative ideas related and innovations in the development of communication social media marketing in global era through activation and digital content, so that it can further develop to increase purchasing decisions fashion product after pandemic.
Factors Affecting the Financial Performance of Local Governments
Authors:   Accounting Departement, Economic and Business Faculty, Universitas Komputer Indonesia, Indonesia, Widilestariningtyas Ony , Alifa Mia Nur ,   Accounting Departement, Economic and Business Faculty, Universitas Komputer Indonesia, Indonesia, Henny H ,   Engenering Industry, Engenering and Computer Science Faculty, Universitas Komputer Indonesia, Indonesia
Published: March 2023

Problem factors that affect the financial performance of local governments include local taxes and balancing funds. Increasing local tax sources and decreasing balancing funds in Tasikmalaya Regency were not accompanied by increased financial performance, but what happened was a decline in financial performance. The purpose of this study was to determine how much the factors that influence the financial performance of local governments in West Java Province. This research uses descriptive analysis method with verification approach. The secondary data source is 27 LHP (Audit Result Report) in the form of LKPD (Regional Government Performance Report). Descriptive analysis uses descriptive statistics and verification analysis uses multiple linear regression analysis. The results showed that the local tax factor has a positive effect on financial performance and the balancing fund factor has a negative effect on financial performance. So it can be concluded that the most important factor in regional financial performance is increasing local tax revenue as a major component of financial independence for local governments, so that the ability of local governments to develop their territories becomes more flexible in implementing equitable distribution of community welfare in West Java Province.
Mendesain Ulang Tampilan UI Website Desa Sukamukti Menggunakan Metode Design Thinking
Authors: Nurrohmah Siti , Andrian Rian
Published: March 2023

Saat ini website desa menjadi salah satu media informasi berbasis digital yang dapat  membantu pemerintah desa dalam melayani, menampilkan promosi dari seluruh potensi desa yang dimiliki serta menyampaikan berita secara luas. Website Desa ini nantinya akan digunakan untuk mempermudah kinerja serta komunikasi dua arah antara masyarakat dan pihak pemerintah desa. Sering sekali kita menemukan masalah dalam mengakses website desa salah satunya melalui tampilan desain yang kurang informatif dan terlalu kompleks. Hal ini dapat dimulai dari tata letak, jenis huruf, hingga navigasi yang ditampilkan tidak memenuhi aspek User Friendly. Diperlukannya rancangan desain website Desa agar dapat memberikan tampilan yang baik, informatif serta mudah digunakan ketika diakses banyak orang. Metode yang digunakan dalam penelitian ini yaitu metode design thinking yang dipadukan dengan metode pengumpulan data berupa obsevasi, wawancara dan studi literatur. Adapun hasil yang dimiliki setelah menerapkan metode design thinking dalam menyusun rancangan desain website desa yaitu adanya perubahan yang baik dalam tampilan website yang bisa memberikan kemudahan serta kesesuaian dengan kebutuhan user dalam mengakses nya. Penelitian ini dilakukan dengan tujuan untuk menghasilkan desain website desa yang informatif, menarik, mudah dibaca dan mudah diakses oleh masyarakat luas.
Anxiolytic effects of Leishmania braziliensis proteins in a zebrafish animal model
Authors: Sousa Natália Sousa de , Gurgel Rayssa Mirelle Campos , Souza Pedro de Freitas Santos Manzi de , Mesquita Dara da Silva , Nicolete Roberto , Honório Júnior José Eduardo Ribeiro
Published: March 2023

Introduction. Leishmaniasis is among the 22 most neglected diseases worldwide. Few information is related about the evidence of neurological involvement that leishmaniasis can cause due to the ulcerations formed in the skin along short and long term. However, some authors have cited that leishmaniasis can cause inflammation in the central nervous system, which can trigger neuropsychomotor processes such as anxiety. Objective. The present study focuses on the evaluation of the effects of total Leishmania proteins on the central nervous system in the Zebrafish model. Method. Leishmania was initially cultured to extract total proteins by Sonication and Bradford methods. After total protein extraction, the zebrafish were inoculated to observe the symptomatology caused by protein load, and after seven days of inoculation, we performed the behavioral tests (Open Field and Bright & Dark). Results. The fish treated with Leishmania protein showed several cutaneous alterations, as well as behavioral changes. The open field behavioral tests showed a high number of crosses compared to the control group. In the light and dark test, the zebra fish had a longer stay in the light field, and an anxiolytic action was observed in the animals that received the protein administration. Conclusion. The total Leishmania proteins may have an anxiolytic action in the zebrafish model.
Desafios e oportunidades da telessaúde em tempos de pandemia COVID-19
Authors: Andreza Marli Nascimento dos Santos , Rats Joselania Gonçalves Brito , Diniz Cicera Lais Ferreira , Cartaxo Natanael Lucena , Damasceno Maria Jossandra do Nascimento Santos , Ferreira Maria Thayná Nascimento , Dos Santos Vagner Sales , De Santana Willma José
Published: March 2023

A covid-19 interrompeu e desafiou a humanidade para uma vivência cotidiana diferente do seu costume atual. As pessoas tiveram que se reinventar e procurar novas oportunidades para exercer suas funções diárias. Esse conflito com o invisível covid-19 à comunidade da área da saúde precisou usar mecanismos tecnológicos, como a telessaúde para atender a necessidade da população, uma vez que o contágio comunitário acontecia de forma muito rápida e por conseqüência superlotava as unidades de saúde impossibilitando o atendimento mais rápido e seguro.O objetivo deste estudo, foi pesquisar na literatura vigente, os desafios e oportunidades da telessaúde em tempos de pandemia covid-19,trata-se de uma revisão integrativa da literatura, nas seguintes bases de dados: Scientific Eletronic Library Online (SCIELO); Medical Literature Analysis and Retrieval System Online (MEDLINE) e Literatura LatinoAmericana e do Caribe em Ciências da Saúde (LILACS), utilizando os descritores: SUS- Sistema Único de Saúde,telessaúde, covid-19, isolamento social e pandemia. A seleção respeitou critérios de inclusão/exclusão dos artigos disponíveis de forma completa e gratuita, entre os anos de 2018 a 2022, nos idiomas português, inglês e espanhol. Foram excluídos estudos que se mostravam inconclusos e/ou repetitivos. Foram encontrados 23 estudos dos quais 8 cumpriram os critérios previamente estabelecidos e foram incluídos na revisão.Todavia, em virtude dos grandes números de contágios e mortes, a telessaúde se tornou uma ferramenta de bastante utilidade na medicina e na educação. A telessaúde tornou-se um atendimento audiovisual que forneceu segurança e rapidez nos serviços ofertados à população. Portanto, a telessaúde potencializou a saúde sanitária em tempos pandêmicos caracterizando a importância das novas tecnologias para fins humanitários viabilizando a assistência à distância por prestação de serviços remotos aos indivíduos.
Фізична активність і спосіб життя викладачів вищих навачальних закладів у віці 50-65 років.
Authors: Bejga Przemek , Popel’ Sergii
Published: March 2023

Мета роботи – вивчити стиль життя викладачів університету віком 50-65 років в залежності від рівня фізичної активності та її зв’язок з їх поведінковими звичками. Матеріал і методи. Для опитування 150 респондентів була розроблена спеціальна анкета. Проводили антропометричне обстеження, за результатами якого для кожної статево-вікової групи вираховували індекс маси тіла за загальноприйнятою формулою. Всі результати оброблені методом параметричної статистики. Результати. Загальна тенденція всіх респондентів серед більшості опитаних вказує на те, що викладачі похилого віку проводять значну частину вільного часу за телевізором або читанням і дуже мало часу приділяють фізичній активності. Більшість опитаних займаються справами по квартирному господарству, але хочуть займатися громадськими справами. Спостерігається тенденція до некуріння, тільки незнача кількість опитаних курить, а решта ніколи не курила, або припинили курити понад 10 років тому. Велика кількість курців спостерігається серед партнерів опитаних. Більшість мають багато друзів та родичів, які можуть допомогти у досягненні вищого рівня фізичної активності, однак мало партнерів опитаних займаються спортом регулярно. Деякі звички, корисні для здоров’я спостерігаються у життєвих стилях всіх учасників опитування. Висновок. В цілому, отримані дані свідчать про доцільність пошуку ефективних шляхів залучення викладачів вузів передпенсійного віку в активну рекреаційну діяльність. Крім того, проведене дослідження доказало наявність необхідних для цього резервів вільного часу.
Образ жизни, питание, наличие вредных привычек и уровень физической подготовленности подростков 14-15 лет, проживающих в Сибири
Authors: Ivanova G. V. , Kolman O. Y. , Ivanova A.N. , Kudryavtsev M. D.
Published: March 2023

Цель работы – выявить особенности образа жизни, питания, наличия вредных привычек и уровня физической подготовленности подростков 14-15 лет, проживающих в Сибири.  Материал и методы. Методы исследования: анализ и обобщение данных научно-методической и специальной литературы, педагогические наблюдения, анкетный опрос учащихся гимназии № 9 г. Красноярска, методы математической статистики, исследование показателей выносливости учащихся гимназии № 9. Оценка выносливости школьников производилась по 6-минутному бегу (по Г.П. Богданову). Результаты. Выявлено, что в процентном отношении  девочек курит больше, чем мальчиков. Возраст начала курения у мальчиков составляет 5 лет, а у девочек 9 лет. Но при этом число курящих девочек возросло к 13 годам. К 15 годам число закуривших девочек превысило мужскую часть в 4 раза. А количество впервые закуривших мальчиков уменьшилось в 3 раза по сравнению с 13-ти летними. При ответе на вопрос «Пьете ли вы пиво?» 20 человек ответили, что такие напитки пьют «иногда». В результате анкетного опроса об особенностях питания учащихся 8-х классов было выявлено, что школьники реже всего употребляют в течение недели такие ценные продукты с точки зрения рационального питания, как яйцо, творог, крупы, рыбу, молоко и кефир. Большинство школьников предпочитают получать в школьной столовой пиццу, сосиску в тесте, гамбургеры, салаты, пирожки, беляши, соки, фрукты. Опрошенные школьники практически не хотят употреблять такие продукты как рыба, яйцо, бобовые, крупы, молоко. Подростки, профессионально занимающиеся спортом и нарушающие спортивный режим (курящие), хотя и показывают в процентном отношении  более высокие результаты по сравнению с «не спортсменами», но проигрывают в выносливости некурящим спортсменам. Вывод. Выявлены опасные тенденции у подростков Сибири относительно преобладания нездорового образа жизни, нерационального питания, наличия вредных привычек и низкого уровня развития выносливости.
Особливості фізичної підготовленості студентів музичних спеціальностей
Authors: Marynchuk Petro Igorovich
Published: March 2023

На основі аналізу науково методичної літератури та системного аналізу передового досвіду сформовано проблематику процесу фізичної підготовки студентів музичних спеціальностей. За основну мету роботи обрано дослідження рівня фізичної підготовленості майбутніх вчителів музичного мистецтва. Завдання дослідження відображають поступовість досягнення мети та передбачали визначення особливостей фізичної підготовленості студентів музичних спеціальностей та напрямів можливого вдосконалення організаційно-методичних умов здійснення фізичної підготовки студентів. Матеріал і методи: аналіз і узагальнення даних літературних джерел, систематизації, педагогічні методи дослідження (експеримент, тестування), методи математичної статистики. У педагогічному експерименті брали участь 154 студента першого та другого курсу Вінницького училища культури і мистецтв імені М. Д. Леонтовича. Результати. Проведення оцінки фізичної підготовленості студентів дозволило визначити загальну тенденцію погіршення показників за період навчання, за переважною кількістю показників це було статистично достовірне погіршення. За гендерною ознакою найбільших змін під час навчання отримує рівень фізичної підготовленості студенток. Визначено основні напрями вдосконалення процесу фізичного виховання студентів музичних спеціальностей. За результатами виконання рухових тестів спостерігається загальна тенденція погіршення результатів за період навчання. Висновки. Студентки першого курсу навчання мали статистично достовірно (р<0,05) кращі показники  у порівнянні зі студентками другого курсу під час виконання всіх зазначених тестів, окрім тесту, що характеризує рівень прояву швидкості (біг 100 м) та швидкісно-силові якості (стрибок в довжину з місця). На відміну від студенток, у учасників дослідження юнаків, статистично достовірні відмінності показників фізичної підготовленості студентів на різних курсах навчання спостерігались за всіма показниками, окрім тесту «біг 100 м».
Методика формування рухових навичок учнів початкової школи
Authors: Miroshnichenko V.I. , Nizhevskа T.V. , Protasenko A.V.
Published: March 2023

Мета дослідження – вдосконалити методику формування рухових навичок в учнів початкової школи. Завдання дослідження 1. Визначити вплив різних сполучень умов виконання вправ на процес формування рухових навичок в акробатиці (на прикладі перекиду вперед). 2. Визначити моделі залежності рівня навченості досліджуваної вправи від різних сполучень умов їх виконання. Матеріал і методи. В даному дослідженні взяли участь 218 дітей 7 років. З них 107 хлопчиків та 111 дівчаток. За умовами експерименту, окремо для хлопчиків і дівчаток, було створено по вісім дослідних груп, в кожній з яких  було по 12-14 школярів. Методи дослідження: аналіз та узагальнення науково-методичної літератури, педагогічні спостереження, бесіди, педагогічний експеримент, методи планування багатофакторних експериментів, методи математичної статистики. Вплив різних сполучень умов виконання вправ (кількості повторень вправ, тривалості перерви між уроками і повтореннями) на результат навчання перекиду вперед визначався за планом повного факторного експерименту (ПФЕ) типу 23. Результати. Встановлено, що процесу навчання руховим повинні передувати спеціальні завдання, спрямовані на підвищення загального рівня вмінь керувати рухами в просторі, за часом і за ступенем м’язових зусиль. Організація виконання цих завдань найбільш ефективна на основі раціонального сполучення часу їх виконання. В основі навчання цим вмінням є метод термінової і поточної інформації про точність виконуваних вправ. Як методичні прийоми використовуються зорові і слухові обмежувачі рухів. Показана можливість керування процесом формування рухових навичок у школярів 7 років на уроках фізичної культури на основі регресійних моделей. Визначені оптимальні варіанти умов формування рухової навички перекиду вперед  з урахуванням раціонального сполучення кількості повторень вправ, тривалістю перерви між уроками і повтореннями. Результати дослідження дають можливість вчителю фізичної культури оптимізувати процес навчання руховим діям, більш раціонально використовувати час уроку, підвищити його загальну та моторну щільність .
Методика інтегрального розвитку швидкісно-силових якостей та точності кидків у юних баскетболістів 12-13 років
Authors: Kozina Zh.L. , Sobko I.M. , Vilvitskii V.O. , Xiaofei Wang , Borovskii S.V. , Tymko Y.N. , Glyadya S.A. , Minak A.
Published: March 2023

Мета роботи: розробити та експериментально обґрунтувати методику поєднаного розвитку швидкісно-силових якостей та технічної підготовленості баскетболістів 12-13 років. Матеріал і методи. В експерименті брали участь 20 баскетболістів із ХОВУФКС №2, які були поділені на дві групи - експериментальну і контрольну, в кожній по 10 чоловік. В контрольній групі заняття проводились по традиційній методиці, а в експериментальній вводились додаткові вправи на стрибучість та техніку баскетболу. Педагогічні спостереження проводилися в процесі навчально-тренувальних занять. Спостереження велося за діями гравців для візуального визначення якості виконання техніки кидка, а саме - для визначення недоліків та технічних помилок під час кидка м’яча. Проводилися наступні тести: 1. Стрибок вгору по Абалакову. 2. Гравець веде м’яч, робить зупинку на дві ноги і виконує кидок у стрибку.  Фіксується кількість влучань із десяти кидків. 3. Гравець виконує з місця кидки у стрибку з підшагу.  Фіксується кількість влучать із десяти кидків. При математичній обробці первинних матеріалів даного дослідження крім обчислення первинних статистик проводився порівняльний аналіз середніх, котрий здійснювався по t - критерію Стьюдента, а також кореляційний аналіз. Обробка показників здійснювалася за допомогою сучасних комп'ютерних програм - "EXСEL" і "SPSS". Результати. Представлено методику комплексного розвитку швидкісно-силових якостей та технічної підготовленості юних баскетболістів різних ігрових амплуа. Показано, що застосована комплексна методика підготовки баскетболістів сприяла підвищенню практично всіх показників тестування спеціальної фізичної підготовленості, якості техніки виконання кидка.  Розроблена методика позитивно впливає на взаємозв’язок показників стрибучості та точності кидків в баскетболі. Висновок. Розроблена методика є адекватною для рішення завдань навчально-тренувального процесу  для баскетболістів  і може бути рекомендована в широку практику підготовки дитячих баскетбольних команд.
Влияние восстановительного масажа после соревнований на показатели функциональных возможностей квалифицированных волейболисток
Authors: Kozina Zh.L. , Sobko I.M. , Nazarenko D. , Glyadya S.A.
Published: March 2023

Цель: экспериментальное обоснование эффективности применения восстановительного массажа в процессе соревновательной деятельностиквалифицированных волейболисток. Материал. В исследовании приняли участие 24 волейболистки команды высшей лиги Украины "Новатор" г. Хмельницкий, из них 1 заслуженный мастер спорта, 3 мастера спорта, 8 кандидатов в мастера спорта, 12 спортсменок 1 разряда.Контрольная и экспериментальная группы тренировались по идентичным программам в течении сентябрь 2017 - апрель 2018 года.  Однако в экспериментальной группе после каждого соревновательного тура спортсменкам профессиональный массажист делал восстановительный массаж. Применялись следующие тесты: метод лабораторного тестирования по Новакки, методы определения физической работоспособности с помощью функциональных проб. Определялись межгрупповые и внутригрупповые различия по проведенным тестам. Результаты. Применение восстановительного массажа в волейболеоказало положительное воздействие на функциональное состояние и физическую работоспособность квалифицированныхволейболисток. У представительниц экспериментальной группы в тесте Новакки количество ступеней увеличилось на 1, в то время как в контрольной данное количество осталось прежним, что составило для экспериментальной группы 25% от исходного уровня и достоверно при р<0,05. Кроме того, в экспериментальной группе достоверно увеличился также общее время работы (р<0,05). В результате проведения специального теста на работоспособнотость, выявлено достоверные отличияпо показателям ЧСС на первой, второй, третей минуте восстановления в экспериментальной групе. Достоверноеулучшение результатов пробы Генча и Руф'е в контрольной и экспериментальной  группах сведетельствует о повышении общего уровня тренированости организма спортсменок. Выводы. Восстанавливительный массаж является эффективным, быстрым и простым способом качественного восстановления организма. Полученные данные свидетельствуют о целесообразности применения восстановительного массажа в процессе соревновательной деятельности квалифицированных волейболисток для оптимизации функционального состояния и повышения физической работоспособности.