bluuebunny/crossref_metadata_2025 huggingface dataset:
inquietante presencia de la muerte. Su representación en el arte uruguayo en tiempos de la Segunda Guerra Mundial.
Authors: Rey Ashfield William , Kaplan Stein Daniela
Published: December 2023

El impacto de la Segunda Guerra Mundial en Uruguay ha sido tradicionalmente estudiado por la historiografía desde su costado socioeconómico, existiendo un gran vacío al respecto de su huella en el espacio cultural y artístico. El presente artículo se propone analizar, precisamente, aquellos cambios del corpus artístico uruguayo en relación con las representaciones de la muerte –en términos iconográficos, formales y expresivos– a partir de la Segunda Guerra Mundial. Por un lado, se estudian vertientes iconográficas relacionadas a la presencia explícita de la muerte, mientras que por otro se sugiere una serie de obras en las que se desarrollan tópicos y atmósferas que se vinculan de manera indirecta, aunque sin aludir llanamente a ella. Es en este caso donde destaca la presencia melancólica de una manera omnipresente.
Memento mori. Espacio urbano y conmemoración funeraria en los cementerios de Willem Dudok, Jože Plečnik y Francisco Salamone para Hilversum, Liubliana y Azul
Authors: García Carbonero Marta
Published: December 2023

Las políticas higienistas del siglo XVIII separaron al cementerio del templo, relegándolo a la periferia de la ciudad. Ya a principios del siglo XX, la ciudad funcional propuesta por los CIAM planteó una zonificación que ignoraba la conmemoración. Sin embargo, en los años 1930, una serie de proyectos funerarios encargados a arquitectos vinculados con localidades de tamaño moderado ofrecieron la oportunidad de elaborar una relación más estrecha entre la ciudad y el cementerio. Este artículo se propone comparar las propuestas de Jože Plečnik para Liubliana, Eslovenia, Willem Dudok para Hilversum, Holanda, y Francisco Salamone para Azul, Argentina, y examinar cómo sus cementerios fueron el punto de partida para configurar relaciones más estrechas con sus respectivos cascos urbanos y para dotar a esas localidades de una nueva identidad.
morada moderna y contemporánea de la memoria colectiva:
Authors: Lázaro Villaverde Fabricio , Cota Castillejos Edith
Published: December 2023

En el siglo XX dentro del proyecto de Modernidad, la muerte colectiva es una herida abierta en la psique humana, su posible cicatriz en el territorio simbólico son los memoriales como espacios de reflexión y catarsis, donde se ritualizan tragedias y subliman procesos de pérdida y duelo como instrumentos de terapia social que en ocasiones resultan más un olvido que una memoria activa.  
El texto estructura un recorrido a través de dos conceptos: promenade architecturale y memoria, circunscritos al mito griego de Mnemosyne, desde donde observar críticamente una selección de memoriales desde la segunda mitad del siglo XX como genealogía reverberada en memoriales contemporáneos de México y la discusión sobre la pertinencia de ellos como herramienta política de olvido en una sociedad lacerada por tragedias naturales, violencia de estado y delincuencia organizada.
cuerpo vestido que somos
Authors: Eskola Torres Gladys , Minchala Urgilés Rosa , Ortega Campoverde Libia , Patiño Villalba Gladis , Reino Díaz Gloria
Published: December 2023

Este trabajo centra el interés en el “cuerpo vestido” que somos, para acercarnos a los significados y sentidos que asignan los enfermos a la exposición de su cuerpo y a su identificación genérica al ser sometidos al uso de una “bata de hospital”. Es una aproximación a las experiencias que vive el “cuerpo doliente” a través de la interpretación del lenguaje corporal (expresiones motoras y verbales) de un grupo de varones y mujeres (adultos jóvenes, medios y mayores), en el momento de su admisión en un hospital de la Ciudad de Cuenca (Ecuador). Cuarenta enfermos admitidos fueron sujetos de observación participante y el mismo número de enfermeras, con experiencia en admisión y cuidado, ofrecieron testimonios acerca del tema. Las vivencias corresponden a un cuerpo incomodado físicamente, limitado en su movimiento, intimidad y pudor, e ignorado en su identidad.
KOMPARATIVNA ANALIZA FOTONAPONSKIH ELEKTRANA SA MONOFACIJALNIM JUŽNO ORIJENTISANIM I BIFACIJALNIM VERTIKALNIM FOTONAPONSKIM PANELIMA NA PEŠTERSKOJ VISORAVNI
Authors: Lekić Milena , Kuč Milorad , Đurišić Željko ,   University of Belgrade, School of Electrical Engineering, Serbia
Published: December 2023

Bifacial vertically mounted solar panels represent a technical solution that converts solar energy into electricity in a way that overcomes certain disadvantages of conventional monofacial south-facing solar panels, primarily in terms of daily and annual production diagrams, as well as the problem of soiling of panel surfaces. In this paper, the production of a monofacial south-oriented photovoltaic power plant and a bifacial photovoltaic power plant with surfaces oriented east-west were analysed, with reference to the north-south orientation. Also, their correlation with the consumption diagram and the electricity price diagram on the market was analysed. The analysis will include the impact of snowfall, temperature and soiling of the module. The effect of land occupation and the possibility of using it for agricultural purposes will also be considered. Analyses will be performed at a real location using real data on insolation and parameters of photovoltaic modules.
MOGUĆNOST SMANJENJA TRAJANJA VREMENA KVARA U DISTRIBUTIVNOM EES I SMANJENJE ANGAŽOVANJA EKIPA
Authors:   Electrodistibution of Serbia, Ostraćanin Vladimir
Published: December 2023

The paper presents one of the ways to reduce the duration of faults in the distribution power system (DEES). The installation of remotely controlled elements and their introduction into the remote control system also reduces the engagement of teams of on-call electricians and electrical fitters. It is especially important if these elements are on the medium voltage network and if they share leads whose length is several tens of kilometers, where finding the fault is difficult even in good weather. The installation of remotely controlled disconnectors described here is extremely important because a large part of overhead lines of medium voltage (10 and 35 kV) are made with cap porcelain insulators, which are the most inconvenient to find a fault.
JEDAN PRAKTIČNI PRISTUP POVEĆANJU RASPOLOŽIVOSTI VANJSKE SREDNJENAPONSKE NADZEMNE MREŽE
Authors:   HEP ODS ELEKTRA BJELOVAR, Croatia, Popović Josip , Popović Zvonimir ,   HEP ODS ELEKTRA BJELOVAR, Croatia
Published: December 2023

This paper presents a technically justified and easy approach for increasing availability of a middle-voltage overhead power network. It all comes down to the construction of new middle-voltage connections between nearby points of adjacent power lines. The condition for this is operational and technical justification. Experiences with already built link lines are satisfactory. The possibilities of remote control and monitoring of the middle-voltage network are increased. In most cases, unnecessary power interruptions are avoided. The medium voltage lines are no longer exclusively radial. Connection of more and more new distributed power sources in the middle-voltage network results in frequent power flow changes. The middle-voltage network now becomes active.
Needs Assessment for Equitable School Bus Electrification in U.S. School Districts
Authors: Brown Charles T. , Jackson Eleanor
Published: December 2023

The Electric School Bus (ESB) Initiative research team surveyed and spoke to school district staff to understand barriers and enablers for electric school bus adoption and how challenges may vary depending on a district’s diversity, income level, and exposure to air pollutants. This paper provides preliminary ideas about the main barriers faced by school districts, what motivates school districts to transition to electric school buses, what types of technical assistance might help school districts move forward, and how school districts are considering equity in their process. The survey size was non-representative and the findings should be taken only as preliminary hypotheses.
О РАЗРАБОТКЕ ТЕХНОЛОГИИ СНЕКОВОЙ ПРОДУКЦИИ ИЗ РЫБНОГО СЫРЬЯ КАЛИНИНГРАДСКОЙ ОБЛАСТИ
Authors: Федоренко Д. Д. , Халтурина А. А. , Сутугин М. А. , Лютова Е. В.
Published: December 2023

Исследованы ассортимент и стоимость рыбного сырья, снековой продукции из рыбы и кальмара. Разработана технология получения рыбных снеков из сырья Калининградской области – салаки (Clupea harengus membras) и трески (Gadus morhua callarias). Опытным путем установлены оптимальные параметры основных технологических операций. Определены органолептические и физико-химические показатели производственных образцов рыбных снеков и образцов, изготовленных на базе лаборатории кафедры пищевой биотехнологии.
O rosto de Deus na Epístola de Jeremias
Authors: Castro Acquaroli Armando Rafael
Published: December 2023

A Epístola de Jeremias (Br 6) contém uma crítica à idolatria, típica da mentalidade hebraica. Os deuses são ironizados pela sua inércia e incapacidade de agir para auxiliar quem os invoca. Neste artigo, o objetivo é partir do que os deuses não possuem e tentar evidenciar as características do Deus de Israel. Essa é a chamada teologia negativa. Assim, pode-se esboçar uma espécie de “credo” contendo o que é característico de Israel e de seu Deus. O Deus do povo se revela com um nome, “Senhor” e a teologia que lhe está ligada é a do Êxodo, do Deus que liberta o seu povo da escravidão e o conduz à terra prometida. Diante d’Ele todos se prostram, desde os primeiros e mais importantes soberanos até os últimos da terra. Seu domínio se estende do céu à terra, dado que Deus regula os ciclos dos quais a humanidade depende para sobreviver e estabelece governantes que agem por mandato divino.
“Physically this universe is one”: Universal Unity in Swami Vivekananda’s Raja Yoga
Authors: Agnew Éadaoin
Published: December 2023

Swami Vivekananda’s Raja Yoga (1896), the focus of this article, is usually credited with starting the yoga renaissance in the late nineteenth century. The text marks a watershed moment in yoga history when Vivekananda translated and popularised the ancient Indian Yoga Sutras by the sage Patanjali as part of anti-colonial intercultural exchanges between east and west in the fin de siècle. The book’s transnational discourse drew from contemporary new physics and neo-Vedantic philosophy as well as Indian nationalism, pre-Freudian psychology, Western occultism, and modern ideas about physical health, and it issued a radical alternative to the binary oppositions on which imperialist and materialist ideologies rely. Vivekananda elucidates Patanjali’s yogic philosophy but, significantly, he also outlines a practical methodology for achieving Raja yoga’s goal of universal unity. He sets out a praxis that gradually breaks down the boundaries between mind and body, matter and energy, subject and object, and thereby transforms the individual in powerful and positive ways. It was an idealistic goal that appealed to various groups of unconventional heterodox thinkers at the fin de siècle, and it arguably contributed to the spiritual and political revolution that spread in subcultural forms, across Europe and America from the second half of the nineteenth century onward (Gandhi 2006: 121).
Introduction: Religion and Victorian Popular Literature
Authors: Hetherington Naomi
Published: December 2023

The introduction to this special issue of the Victorian Popular Fictions Journal, “Religion and Victorian Popular Literature,” opens by using Mary Ward’s best-seller Robert Elsmere (1888) as a case study for considering how recent critical strategies for engaging with popular texts enable us to paint a different and more complex picture of the Victorian religious landscape. We then explain the different ways in which our international network of contributors reconceptualises the relationship of religion to popular literary genres including the transatlantic social gospel, science writing for children, and popular yoga texts. We identify how topics as diverse as astronomy, copyright, and disaster fiction, which have often been examined through a primarily secular lens, can be better understood by considering the role religion played in their formation and articulation within and through popular literature. Drawing together threads shared between the seven articles in the special issue, we outline its key thematic contributions in exploring the role of religion to the formation of new literary markets and genres, revising the “conflict thesis” between religion and science, and the importance of popular literary forms in constructing and communicating theological ideas, as well as responding to recent calls to decolonise Victorian Studies.
(Sex) Religion Sells! The Preacher, the Journalist and the Novel
Authors: Goodwyn Helena
Published: December 2023

The American minister Charles Monroe Sheldon published the “runaway bestseller” In His Steps “What Would Jesus Do?” in 1896. The initial, and stupendous, popularity of Sheldon’s social gospel novel has not yet been scrutinised in relation to its historical antecedents. By 1899 the weekly Outlook remarked on the transatlantic cross-over of the book, stating: “wherever one went in London, whether on trains or buses, in bookstores or shops, [one] found people talking about In His Steps.” In that same year W. T. Stead reissued his non-fiction book If Christ Came to Chicago, which had first been published in Chicago in 1894, two years before Sheldon’s sermon-story. The 1899 title page declared: “The Precursor of ‘In His Steps’/ If Christ came to Chicago!... /What Would Jesus Do?” Stead’s non-fiction book sold well on both sides of the Atlantic, before and after Sheldon’s novel was published. So, was this simply a marketing stunt designed to attract more readers? Or did Stead’s new title register deeper concerns about the relationship between fiction, journalism, and the social gospel movement? Investigating the somewhat vexed relationship between these two texts, this article traces the transatlantic roots of In His Steps. Comparing the afterlife of the novel with its immediate non-fiction ancestor, I explore the synergetic, if at times uncomfortable, relationship that developed between the social gospel movement and the periodical press at the end of the nineteenth century.
A Case Series of Sotalol-induced Torsade de Pointes in Patients with Atrial Fibrillation – A Tale with a Twist
Authors: Tan H H , Hsu L F , Kam R M L , Chua T , Teo W S
Published: December 2023

Introduction: Sotalol is a potent antiarrhythmic often used in patients with atrial fibrillation. However, it has been associated with a risk of provoking other potentially dangerous arrhythmias, especially if used in high doses and in patients with uncorrected electrolyte imbalance or impaired renal and cardiac function.

Clinical Picture: We present 4 patients with atrial fibrillation treated with sotalol who developed torsade de pointes due to marked prolongation of the QT interval. While 1 patient had renal failure, all had normal left ventricular function. One patient had been treated with sotalol for more than 10 months before developing torsade de pointes precipitated by hypokalaemia, while another had tolerated sotalol for a 3-month period before the drug was discontinued, and only developed torsade de pointes when the drug was restarted 2 years later. Significantly, the doses used in all patients were relatively low, in contrast to most other reported cases where higher doses were used.

Conclusion: As with all antiarrhythmic therapy, these cases illustrate the need for close follow-up of patients treated with sotalol, even if relatively low doses are used. In addition, patients who had previously tolerated the drug well are still susceptible to its proarrhythmic effects.
The Influence of Sales Promotion and Shopping Lifestyle on Impulsive Buying Behavior of Mr DIY in Palembang City
Authors: Manalu Anggriani Br , Changreani Evelyn
Published: December 2023

This research was conducted to analyze the influence of Sales Promotion and Shopping Lifestyle on Impulse Buying among Mr DIY consumers in Palembang City. The growth of the retail industry and changes in consumer lifestyles require a deeper understanding of the factors that influence impulse shopping behavior. This research tries to answer the problem regarding the influence of Sales Promotion and Shopping Lifestyle on the tendency to shop impulsively at stores like Mr DIY. The purpose of this research is to find out whether Sales Promotion and Shopping Lifestyle influence Impulse Buying in Mr DIY, Palembang City. This research aims to provide a clear and specific picture of the factors that influence consumers' impulsive shopping decisions. This research uses a quantitative approach with non-probability sampling techniques and a purposive sampling approach to select 100 respondents. Data analysis was carried out using statistical methods which included regression to test the influence of the Sales Promotion and Shopping Lifestyle variables on Impulse Buying. The population of this research is Mr DIY consumers in Palembang City. A sample of 100 respondents was selected purposively to achieve appropriate representation. The research results show that Sales Promotion has no significant effect on Impulse Buying, while Shopping Lifestyle has a positive effect on the impulsive shopping behavior of Mr DIY consumers in Palembang City. In this research it can be concluded that consumer shopping lifestyles influence impulsive shopping tendencies more than sales promotions. The implications of these findings can help design more effective marketing strategies. This research contributes to the understanding of consumer behavior and retail marketing strategies. Knowing that lifestyle shopping has a stronger influence can help stores like Mr DIY to devise promotional and sales strategies that better suit consumer preferences, enrich the literature on impulse shopping, and provide guidance for further research.
Dermatological Manifestations in Cirrhotic Patients: A Comprehensive Review
Authors:   Hospital de Especialidades Dr. Bernardo Sepúlveda Gutiérrez. Centro Médico Nacional Siglo XXI. Instituto Mexicano del Seguro Social., Jiménez Hiebda Sofía Martínez
Published: December 2023

Cirrhosis of the liver is a complex and debilitating condition characterized by the progressive deterioration of hepatic function due to chronic liver disease. While hepatic dysfunction remains central to its pathophysiology, cirrhosis often presents with a myriad of extrinsic manifestations that extend beyond the hepatobiliary system. Dermatological manifestations in cirrhotic patients are a frequently encountered yet underappreciated facet of this multisystem disorder. These cutaneous signs can serve as invaluable clinical indicators, aiding in both the early detection and management of cirrhosis. This comprehensive review article aims to elucidate the diverse dermatological presentations associated with cirrhosis, shedding light on their underlying mechanisms, clinical relevance, and diagnostic significance. We delve into the pathophysiological basis of these dermatological manifestations, encompassing conditions such as spider angiomas, palmar erythema, pruritus, and jaundice-associated changes, among others. Furthermore, we explore the intricate interplay between liver dysfunction, immune dysregulation, and the skin, providing a holistic perspective on the dermatological dimension of cirrhosis. Through this comprehensive analysis, we aspire to enhance clinicians' awareness and understanding of these dermatological cues, ultimately contributing to improved patient care, early intervention, and a deeper appreciation of the intricate relationship between the liver and the integumentary system.
Mindfulness and Training Discipline among Martial Arts Students in Beijing, China
Authors:   Emilio Aguinaldo College, Manila, Philippines, Longlong Shi
Published: December 2023

The study investigates the relationship between mindfulness and training discipline among martial arts athletes at a Beijing sports university. The research used a quantitative-correlational design. A researcher-made questionnaire was used as the primary instrument. The data was analyzed using descriptive and inferential statistics. The correlation coefficient between mindfulness level and training discipline was .703, with a significance level of .031. However, the significance level is less than the threshold of.05. Therefore, the null hypothesis is accepted, indicating that factors other than mindfulness level might influence martial arts athletes' training discipline.
Factors Affecting the Success of Tourism Village Development in Kampung Bandar, Pekanbaru City
Authors:   Graduate Student in the Master's Program of Regional and Rural Planning Postgraduate Program, University Riau Address: Jl. Pattimura No.09, Building I, Gobah, Pekanbaru, Cahyadi Ayat , Zulkarnaini Zulkarnaini ,   Faculty Member in the Master's Program of Regional and Rural Planning Postgraduate Program, University Riau Address: Jl. Pattimura No.09, Building I, Gobah, Pekanbaru, Zulkarnain Zulkarnain ,   Faculty Member in the Master's Program of Environmental SciencePostgraduate Program, University Riau Address: Jl. Pattimura No.09, Building I, Gobah, Pekanbaru
Published: December 2023

Research was conducted in Kampung Bandar, Pekanbaru City, to identify the factors influencing the success of Tourism Village development and to assess the economic impact of tourism activities. Data analysis was carried out using path analysis, involving 60 participants, including visitors, vendors, and government representatives. The research findings indicate that the factors influencing the success of tourism village development are accessibility, attractions, and the tourism market. There is a significant correlation between the success of tourism village development and the economic impact of Kampung Bandar Tourism Village in Pekanbaru City.
Professional Coaching and Sports Adaptability of Students in Dance Sports
Authors:   Emilio Aguinaldo College, Manila, Philippines, Fang Yin
Published: December 2023

This study aimed to shed light on the relationship between the level of sports coaching professionalism and sports adaptability among university students. This study employed a quantitative comparative correlational research design to investigate the relationship between sport coaching professionalism and sports adaptability among university students. The research included 80 Physical Education (PE) students from a chosen university in Xian, China, who were selected using a census sampling technique. The questionnaire was divided into three parts: demographic profile, assessment of sport coaching professionalism, and current level of sports adaptability. The data analysis included descriptive statistics and inferential statistical tests to determine the relationship in the assessment of sport coaching professionalism and sports adaptability among university students. It was evident that there was a negative correlation of -0.168 between the level of sport coaching professionalism and the current level of sports adaptability among the university students. However, the significance level (.137) indicated that this correlation was not statistically significant. It was implied that there was no strong linear relationship between the students' assessment of the level of sport coaching professionalism and their current sports adaptability.
The Power of Ethical Leadership in Advancing Social Justice and Equity in Physical Education Programs in Beijing, China
Authors:   Emilio Aguinaldo College, Manila, Philippines, Xuezeng Zheng
Published: December 2023

The study aimed to investigate the impact of the pandemic on physical education teachers and coaches in Beijing, China. A sample of 132 teachers was selected using random sampling. A survey questionnaire was developed to collect data on ethical leadership practices, social justice outcomes, and equity outcomes in physical education programs. The Likert-type scale measured the perceived role of program administrators in promoting ethical leadership. Data analysis used descriptive statistics, Pearson-R, the t-test, and ANOVA to test hypotheses. The study examined the correlation between ethical leadership and social justice in physical education programs. The results indicated that there was no significant correlation found between perceptions of ethical leadership and social justice promotion. This suggests that variations in individuals' perceptions of ethical leadership were not strongly linked to variations in their perceptions of social justice promotion.
Los libros de la nueva izquierda en tirajes masivos: la Serie Popular de Ediciones Era (1969-1989)
Authors: Bello Kenya
Published: December 2023

En estas páginas se analiza la colección Serie Popular publicada por Ediciones Era, entre 1969 y 1989, como parte de las iniciativas que tuvieron las izquierdas mexicanas del último tercio del siglo xx para difundir corrientes ligadas a la nueva izquierda, al tiempo que se perseguía a un público masivo para sus publicaciones. Desde la historia sociocultural de la edición, se busca contribuir a un mayor conocimiento de los usos políticos de las colecciones populares, así como de la circulación de corrientes intelectuales ligadas a la izquierda en el contexto de la guerra fría. En consecuencia, se reconstruyó el catálogo y se hizo énfasis en la perspectiva de los productores a partir de sus estrategias editoriales.
La revolución chilena vista desde los documentos del Partido Comunista de la Unión Soviética
Authors: Schelchkov Andrey
Published: December 2023

La experiencia de la Unidad Popular en Chile tuvo un fuerte impacto a escala internacional, sobre todo al interior del movimiento comunista y socialista. Un factor importante en el proceso chileno fueron las relaciones con los países del bloque socialista y, especialmente, con la URSS. Para ella, la experiencia chilena se convirtió en un nuevo desafío, en el marco de los paradigmas de la Guerra Fría. Pero, a pesar de las declaraciones públicas de apoyo a la “vía chilena al socialismo”, los países socialistas mantuvieron una posición cautelosa. En este sentido, el presente texto pretende exponer y analizar las pautas de la política soviética frente al Chile de la UP en materia ideológica, política y económica, basándose en la documentación del archivo del CC del Partido Comunista de la Unión Soviética y tratando de construir una narrativa del proceso histórico visto desde los gabinetes gubernamentales de Moscú.
“Nuestro internacionalismo” Nación, racialización, clase y anarquismo en Brasil (1890-1920)
Authors: Dos Santos Kauan Willian
Published: December 2023

Este artículo pretende abordar algunos aspectos de los debates anarquistas producidos en el contexto de la Primera República en Brasil, en el que se involucraron conceptos como el de nación, raza y clase en la construcción del anarquismo. Aunque construido y desarrollado de forma transnacional y bajo un programa internacionalista, el anarquismo no era ajeno a las transformaciones estructurales que forjaron prácticas y discursos nacionales. Así, el internacionalismo fue muchas veces utilizado solo de manera retórica, coexistiendo en tensión con redes transnacionales de inmigrantes de una misma nacionalidad. Si bien esto pudo obstaculizar el desarrollo de una clase obrera nacional y fortalecer discursos etnocéntricos, en ocasiones, anarquistas y sindicalistas revolucionarios aprovecharon dichos imaginarios nacionales para difundir sus ideas, uniendo esa tendencia a un internacionalismo práctico practicado entre brasileños e inmigrantes, lo que acabó combatiendo la discriminación racial. De este modo, el internacionalismo práctico permitió la construcción de grupos sindicales y editoriales que reunieron a trabajadores nativos e inmigrantes de distintos orígenes nacionales y étnicos, con redes de militantes y grupos anarquistas alrededor del mundo.
Sobre la inferioridad de la mujer. Conferencia inédita de Juana Rouco Buela
Authors: Rouco Buela Juana
Published: December 2023

Sobre la inferioridad de la mujer. Conferencia inédita de Juana Rouco Buela
De la invisibilidad al mundo
Authors: Aloise Ítalo
Published: December 2023

El núcleo central de este editorial es dar a conocer los logros alcanzados por nuestra Revista Dermatología Argentina durante este año. La misma inició su publicación en 1995 bajo la presidencia de la Prof. Dra Ana Kaminsky, y fue el Prof. Dr Alberto Woscoff su primer Director y actual Director Honorario.
Sin dudas los paradigmas de la medicina han cambiado, y mucho, desde sus comienzos. El trabajo ad honoren ha sido sepultado hace un par de años, lo que nos motivó a implementar ciertos cambios. Conociendo su existencia online desde 2002, decidimos disminuir el número de impresiones al mínimo, al igual que las ediciones anuales, pasando de cuatro-cinco a solo tres, además de impulsar que la mayor cantidad de miembros la lea online. Esto significó una reducción importante en los costos de edición y envío, lo que permitió conseguir una remuneración para la Directora y Secretaria de redacción. De esta forma, se reconoce el esfuerzo realizado e incentivamos a otros miembros de la Comisión a querer estar en ese lugar que otorga un enorme caudal honorífico y a partir de ahora, un monto económico.
Estudio retrospectivo de 10 pacientes adultos con enfermedad ampollar autoinmune por inmunoglobulina A lineal
Authors: Merenzon Sabrina , Di Milia Mónica Beatriz , Cabral Campana Luciana , Dickson Cinthia , Label Marcelo Gabriel
Published: December 2023

Antecedentes: la enfermedad ampollar autoinmune por IgA lineal (EIAL) es una afección adquirida, crónica, poco frecuente, que cursa con ampollas subepidérmicas y presencia de depósitos de IgA en un patrón lineal, en la zona de la membrana basal (ZMB), observados por inmunofluorescencia directa (IFD) o técnicas inmunohistoquímicas.

Objetivo: determinar las características epidemiológicas y clínicas, y la respuesta al tratamiento de los pacientes con EIAL.

Diseño: estudio descriptivo, observacional y retrospectivo.

Materiales y métodos: se evaluaron las historias clínicas de 648 pacientes que asistieron al sector de enfermedades ampollares autoinmunes del Servicio de Dermatología del Hospital General de Agudos Dr. José María Ramos Mejía entre noviembre de 1997 y diciembre de 2021. Se incluyeron pacientes de ambos sexos mayores de 18 años que presentaban síntomas clínicos y resultados de IFD compatibles con EIAL.

Resultados: se estudió la evolución de 10 pacientes con diagnóstico de EIAL (1,54% del total de los pacientes). El sexo más afectado fue el femenino. La edad promedio de presentación fue de 52,5 años. Solo el 20% tenían compromiso mucoso. Todos los pacientes presentaron en la IFD depósitos lineales de IgA en la ZMB. El 60% fueron tratados con dapsona en combinación con metilprednisona.

Conclusiones: destacamos la heterogeneidad del cuadro clínico y que la entidad se define por el hallazgo de depósitos de IgA en la IFD, con un patrón lineal siguiendo la ZMB. En este estudio, a diferencia de lo publicado en la literatura, la edad de presentación fue menor, el compromiso mucoso fue menos frecuente y se observó el estrés emocional como un factor desencadenante no mencionado en la bibliografía.
O Programa de Garantia Agropecuária (PROAGRO) como um instrumento de defesa sanitária vegetal no Brasil: o caso do milho no período 2015 a 2022
Authors:   , Rodrigues Marcelo da Silva
Published: December 2023

A agricultura é uma atividade que apresenta os maiores riscos de produção em comparação às outras atividades. Este setor não depende apenas do uso racional e eficiente de insumos como adubos e defensivos, mas também do comportamento do mercado, do uso adequado das tecnologias e das condições climáticas e bióticas, como o ataque de pragas e doença. No campo do seguro rural, os esforços de prevenção e mitigação visam reduzir a probabilidade de ocorrência de eventos adversos e/ou reduzir o impacto dos eventos. A transferência do risco é o processo de redistribuição dos efeitos econômicos negativos de um evento entre um grupo de atores. Esse processo é a razão da existência do seguro agrícola. Nesse contexto, o crédito rural governamental desempenha um papel fundamental no desenvolvimento e na sustentabilidade do setor agropecuário e está diretamente associado ao PROAGRO. Sendo assim, esta pesquisa teve como objetivo geral avaliar o uso do programa governamental de seguro rural chamado PROAGRO e seus benefícios e potencialidades como instrumento de defesa sanitária vegetal, uma vez que ele pode cobrir possíveis ocorrências associadas a ataque de pragas e doenças no Brasil. O foco foi na cultura do milho no período de 2015 a 2022. Trata-se de uma pesquisa com uma abordagem análise exploratória de dados. Foram utilizados revisão bibliográfica e acesso a banco de dados em meio impresso e eletrônico. A análise dos dados levantados revelou uma crescente importância dos eventos relacionados ao ataque de pragas e doenças a partir de 2015, mostrando que há um potencial importante de uso do PROAGRO como ferramenta de defesa sanitária vegetal na agricultura brasileira. Palavras-chave: PROAGRO. Defesa sanitária vegetal. Instrumento de defesa.
Preparação de nanoesfera magnética funcionalizada com L-histidina para o enriquecimento de proteínas de baixa abundância em amostra de soro sanguíneo: um foco em biomarcadores de doenças humanas
Authors:   , Vieira Edileuza Marcelo
Published: December 2023

No presente estudo, a eficiência da nanoesfera magnética (Fe 3O4) revestida com L- histidina (L-his) foi avaliada para enriquecer proteínas de baixa abundância no soro humano. A análise quimiométrica forneceu condições ótimas para concentrar proteínas de baixa abundância, reduzindo a faixa dinâmica dos níveis de proteína na amostra de soro. Três fatores independentes (temperatura, razão de massa e pH) foram testados. A condição ótima alcançada foi usando temperatura (42°C), proporção (3:1, nanomaterial/amostra) e pH (5,5). O estudo cinético revelou que a adsorção de proteínas na superfície da nanoesfera magnética monocamada segue um modelo de pseudo- segunda ordem com R2=0,9153. Experimentos de isoterma de adsorção revelaram alta capacidade de adsorção de proteínas na superfície da nanoesfera, indicando uma capacidade máxima teórica de adsorção (q max) de 123,45 mg g-1. A eficiência do enriquecimento de proteínas de baixa abundância na amostra de soro foi avaliada por eletroforese em gel (SDS-PAGE). Além disso, quando comparado ao método que utiliza solvente orgânico (acetonitrila), o Fe3O4@L-his apresentou eficiência adequada para simplificar a amostra de soro. Usando MALDI-TOF/TOF, aproximadamente 50 proteínas foram identificadas usando Fe3O4@L-his. Esses resultados mostram que Fe 3O4@L-his pode ser uma alternativa rápida, robusta e simples para enriquecer proteínas de baixa abundância no soro humano, surgindo como uma importante estratégia na busca por biomarcadores de doenças humanas. Palavras-chave: Proteômica, biomarcadores, preparo de amostra, nanomaterial, otimização multivariada.
Clinical outcomes of palliative 3-dimensional conformal external beam gastric radiotherapy: single center experience
Authors: ÖZTÜRK Hüseyin Furkan , ALTINIŞIK İNAN Gonca , ARAL İpek Pınar , AYTAÇ ARSLAN Suheyla , GÖKHAN AÇIKGÖZ Sedef , BEYAZ Havva , TEZCAN Yılmaz
Published: December 2023

Aim: Patients diagnosed with locally advanced and/or metastatic gastric cancer and who cannot undergo surgery may need palliative treatment during their follow-up. There is scarce data about outcomes of palliative gastric radiotherapy (RT). In this study, we aimed to investigate the effect of 3-D external beam RT on oncological outcomes, as a non-invasive method.Material and Method: From 2013 to 2017, sixteen gastric cancer patients treated with palliative external RT in our institutional clinic were evaluated. Only patients who received palliative gastric radiotherapy for obstruction, pain and bleeding were analyzed, and patients who had previously received RT to the abdomen or who were given RT for adjuvant purposes were not included in the analysis. Results: Seven patients (43%) were not able to finish the planned palliative course. Thirty Gray with 10 fractions was the most planned RT schedule. Almost half of the patients (%56) received chemotherapy before RT. Overall survival was found to be median 2 months. Median survival was better in patients who were able to receive 28 Gy bioequivalent dose (4 vs 0.3 months, p≤0.00). Purpose of palliation also found to be a significant factor on survival. Patients who were referred for pain have found to be better survival rather than bleeding and obstruction (13 vs 0.7 months, p=0.03).Conclusion: External radiotherapy is an easily applicable and effective method for palliation in gastric cancer patients. Early referral for radiotherapy in patients who need palliation may increase oncological outcomes. It has been observed that the prognosis is worse in patients who received palliative radiotherapy due to gastric bleeding and obstruction.
Prognostic factors for survival in pancreatic cancer patients received radiotherapy: a single-center experience
Authors: ALKIŞ Hilal
Published: December 2023

Aim: To investigate survival outcomes and factors affecting the prognosis of patients with pancreatic cancer (PC) who received radiotherapy (RT).Material and Method: A total of 73 patients with PC who received RT between 2013 and 2021 were included in the study. Clinical, demographic, and histopathological features of the patients, and the goal of RT (adjuvant, definitive, neoadjuvant, or palliative) were recorded. Results: Median age of the patients was 62 (37-78). Male to female ratio was 1.6. In patients treated with adjuvant (n=52), definitive (n=13), and palliative (n=7) RT, median overall survival (OS) was 25.7 (11.6-39.7), 16 (7-67), and 9 (5-52) months, respectively. Survival time of 1 patient who received neoadjuvant RT was 26.6 months. Lymph node ratio (LNR) was significantly associated with OS. Patients with LNR ≤0.4 had better survival compared to those with LNR >0.4 (p=0.003). Furthermore, patients with LNR ≤0.4 and received adjuvant RT survived longer than the rest of the patients (12.1 vs. 7.7 months, p=0.001). Larger tumors (p=0.04) and LNR (p=0.003) were associated with poorer survival in univariate analysis, however, in the multivariate analysis, OS was found significantly affected only by LNR (p=0.01). Other factors were not found associated with survival. Conclusion: LNR had a strong correlation with OS in PC patients treated with radiation. Smaller LNR was associated with better survival in patients who received RT in the adjuvant setting.
Is it possible to reduce treatment costs in distal radius torus fractures?
Authors: ALIÇ Taner
Published: December 2023

Aim: The aim of the study was to evaluate the effect of parental information on the number of radiological examinations, the number of orthopedics outpatient visits, the duration of early orthopedic outpatient admission, the fracture recovery scores of reduction, and the cost of treatment of torus fractures in children in in the emergency service.Material and Method: A total of 85 patients having stable torus fractures, aged between 0-16 years have been included to the longituidinal study during the period of first of April 1, 2020 and first of September, 2022. A total of 44 patients whose parents are not informed were evaluated in the emergency department and were transfered to the Orthopedics polyclinic (No Information group- No-INF), whereas 41 patients were evaluated by the Orthopedist in the emergency department and their parents were informed directly (Information group- INF). The groupd were compared in terms of the duration of the first admission to the orthopedic polyclinic, the number of applications to the orthopedic polyclinic, the number of radiological examinations performed, whether reduction has been performed, fracture healing scores and current treatment costs and correlation was analyzed. Results: The MAYO Wrist Score (p=0.80), age (p=0.712), gender (p=0.815), and complications (p=0.482) did not differ significantly between the No-INF and INF groups. Patients in the INF group whose parents have been directly informed in the emergency department had lower orthopedic polyclinic application rates (p<0.001), longer delay for the first orthopedic polyclinic admission (p<0.001) and a lower probability and/or less number of X-Ray evaluation(p<0.001). Correlation between the variables such as Patient’s Modified MAYO Wrist Scores, the number of orthopedic polyclinic visits, the first orthopedic polyclinic admission time, the reduction procedure and the number of X-Rays was not ststistically significant (p>0.05). Findings show that additional tests and procedures such as radiography has increased the costs of 6-41% in the present study. Conclusion: It can be concluded that adequate information in the emergency services for parents of children with stable torus fractures might provide a reduction in treatment costs due to lower orthopaedic polyclinic admission and reduced radiographic examination. Wrist MAYO scores have not been affected application of reduction, radiographic evaluation, polyclinic admission and time.
Association of serum uric acid/albumin ratio with completely occluded infarct-related artery in patients with non-ST-segment elevation myocardial infarction
Authors: KARAYİĞİT Orhan
Published: December 2023

Aim: Infarct-related artery (IRA) patency before primary percutaneous coronary intervention (pPCI) is linked to improved clinical outcomes and lower mortality in patients with acute coronary syndrome. The purpose of this research was to examine the association between serum uric acid/albumin ratio (UAR) and IRA patency in patients with non-ST-segment elevation myocardial infarction (NSTEMI).Material and Method: We evaluated 430 consecutive patients with NSTEMI in total retrospectively. The study population was divided into 2 groups according to the IRA patency as assessed by the degree of Thrombolysis in Myocardial Infarction (TIMI) flow before pPCI. As a result, completely occluded IRA was defined as TIMI grade 0-1, while patent IRA was defined as TIMI grade 2-3.Results: IRA was found to be occluded in 110 (25.5%) patients prior to the procedure. UAR level (p=<0.001) was found to be higher among the patients with IRA occlusion when compared to the patent group. Regression analysis revealed that UAR (OR:3.125; 95% CI:1.186-8.232, p<0.001), left ventricular ejection fraction (OR:0.917, 95% CI:0.885-0.951, p<0.001) and culprit artery diameter (OR:0.917, 95% CI:0.885-0.951, p<0.001) were independent predictors for an occluded IRA. An UAR cut-off value of >1.40 was detected to prognosticate the occluded IRA with 62.7% sensitivity and 63.8% specificity (AUC: 0.722, 95% CI: 0.671-0.773, p<0.001).Conclusion: UAR is an independent predictor of preprocedural IRA patency in patients with NSTEMI. Thus, UAR may be an easily accessible parameter to diagnose high-risk NSTEMI patients who would benefit from an immediate invasive strategy (<2 hours).
Retrospective analysis of clinical characteristics, diagnosis, treatment and complications of children with acute pancreatitis: single-center results
Authors: BAŞKOCAGİL Ersin , GÜMÜŞ Meltem , YORULMAZ Alaaddin , EMİROĞLU Halil Haldun
Published: December 2023

Aim: In the present study, the purpose was to evaluate the demographic and clinical data of pediatric patients, who had pancreatitis, who were followed up as outpatients or in the wards, and to evaluate the treatment modalities used along with nutritional status, length of hospital stays, and complications.

Methods: This study was carried out by retrospectively evaluating the files of 166 patients identified by INSPPIRE Criteria who were followed up at the Department of Pediatric Gastroenterology, Faculty of Medicine, at xx University between 2011 and 2021. The age, gender, height, weight, known disease, drugs used, follow-up periods by us, complaints on admission, the etiological reason for the diagnosis, type of pancreatitis, length of hospital stay, treatment modalities applied, and complications of the patients were recorded. The PAPPS Scores, Ranson Admission Scores, and Ranson 48th hour Scores of the patients were analyzed.

Results: A total of 120 patients (72.3%) had AP, 25 patients (15.1%) had CP, and 21 patient (12.7%) had ARP. According to the Atlanta Criteria, 82.5% were mild and 17.5% were moderate. The most common complaint was abdominal pain and the most common cause was found to be idiopathic. There was a weak and positive correlation between the PAPPS Score, Ranson Admission Score, and length of hospital stay.

Conclusion: In the diagnosis and follow-up of pancreatitis, it is important to determine the severity of the disease and to reveal the etiology. Establishing and applying standard approaches for early diagnosis and treatment of patients will lead to prognostic improvement and prevent related complications.
Comparative evaluation of retrograde intrarenal surgery using ureteral access sheath and fluoroscopy: a retrospective analysis on kidney stone treatment
Authors: DOĞAN Kazım
Published: December 2023

Aims: This study aimed to investigate the outcomes of retrograde intrarenal surgery (RIRS) with and without the utilization of ureteral access sheath (UAS) and fluoroscopy for treating kidney stones and its implications on postoperative complications.

Methods: Employing a retrospective design, we analyzed the records of 314 patients subjected to RIRS due to kidney stones. Patients were categorized into two groups based on the application of fluoroscopy and UAS (Group 1) versus non-application (Group 2). Various metrics, including stone-free rates, residual stone rates, and postoperative complications, were compared between the groups.

Results: The results showed no significant differences between the two groups regarding patient age, stone size, and several demographic parameters. However, there was a considerable reduction in operation duration in Group 2 (20.96±5.97 minutes) compared to Group 1 (26.15±5.41 minutes), where UAS and fluoroscopy were applied, with p=0.001. Furthermore, post-treatment results highlighted a decline in residual stone rates and an enhancement in stone-free rates, though differences between groups were not significant. The incidence of postoperative complications, like fever, urinary tract infections, and ureteral stenosis, was assessed, revealing no differences between the two groups.

Conclusion: The application of RIRS without UAS and fluoroscopy appears to be a promising approach to treating kidney stones, offering similar outcomes regarding stone removal efficacy and postoperative complications compared to the traditional method with UAS and fluoroscopy. This research emphasizes the potential of a less invasive method, warranting further studies to understand its broad implications.