bluuebunny/crossref_metadata_2025 huggingface dataset:
Produção leiteira de vacas primíparas de acordo com o sexo da cria
Authors: Nunes Sabrina Maria , Moraes Gilson Passos de , Rocha Júnior José Maurício da , Pratas Alice  Glycerio de Freitas
Published: August 2023

Milk production in Brazil occupies the fourth position in the world ranking, with milk corresponding to one of the six essential products for Brazilian agriculture. The present study aimed to analyze the influence of the calf's sex at first calving on milk production (kg/milk/lactation) of cows. Using data from 43 bovine females, in which they were divided into two groups: Group I (male calving primiparous cows – MCPC) and Group II (female calving primiparous cows – FCPC). Subsequently, the data collected regarding milk production (kg of milk/lactation) were subjected to the normality test and analysis of variance, using the Tukey test. And the statistical analyses were performed using the public domain SISVAR 5.6 software. Dairy production of female calving primiparous cows (8,635.5) showed higher milk production (P < 0.05) than male calving primiparous cows (7,415.5), demonstrating in general aspects the existence of a positive effect of the sex of the calf in the milk production of primiparous cows. In conclusion, the sex of the calf creates an influence on milk production in the first lactation, where female calving primiparous cows tend to produce more milk.
Diabetes mellitus secundário a piometra de coto: Relato de caso
Authors: Lima Juliana Pereira , Da Silva Marcio Correia , Chaves Marcio da Silva , Dos Santos Maria Eduarda Cerqueira Alcântara , Novaes Mariana Antunes Siqueira , De Carvalho Mariana Peterson Félix , Carneiro Rodrigo Lima
Published: August 2023

Diabetes mellitus is a disease with moderate incidence in dogs, characterized as a disorder in the endocrine pancreas with a decrease in serum insulin levels, its main symptoms being polyuria, polydipsia, polyphagia and glycosuria. This report addresses the care of a ten-year-old, spayed, mongrel, female dog, weighing 16.7 kg. Blood count and serum biochemical profile tests were collected, requested for an inpatient procedure, and showed alterations in total glycemia, alkaline phosphatase, alanine aminotransferase and total platelets, revealing a clinical picture of diabetes mellitus. Complementary tests were performed to confirm the diagnosis, such as urinalysis and blood glucose tests during fasting. Upon ultrasound, a stump pyometra was identified and surgical intervention was chosen. After surgery and drug treatment with insulin, the patient showed improvement and remains stable to date. However, she became insulin-dependent, having suffered permanent blindness due to diabetic cataracts.
Correção de hérnia umbilical em potra por meio da técnica aberta
Authors: Almeida Daniel Sérgio de Faria , De Sousa Junior Pedro Ferreira , Cardoso Davi Soares Serra , Sedrim Filho Aldmizio Pereira , Ohashi Gabriel Satoru , Lima Dayanne Anunciação Silva Dantas , Henrique Fernanda Vieira , Lima Wagner Costa , Porfírio Kenney de Paiva , Da Silva Filho Manoel Lopes da Silva Filho
Published: August 2023

Umbilical hernia is a common condition in equids, characterized by a protrusion of organs or structures from the abdominal cavity through an umbilical ring that did not undergo involution, which can lead to colic episodes, loop strangulation, and impact the animal's aesthetics. Its causes can be congenital or acquired. Diagnosis is made through palpation and identification of the hernial ring, along with an ultrasound examination to detect the hernial contents. Treatment consists of manual or surgical reduction of the hernia. The reported case involves a 7-month-old Quarter Horse filly, diagnosed with a 5 cm umbilical hernia, without incarceration or discomfort. Diagnosis was made through palpation, and the treatment involved open herniorrhaphy, with good recovery and post-operative healing.
Efektifitas Penggunaan Metode Problem Solving dalam Meningkatkan Hasil Belajar Siswa Di SMP Negeri 5 Parepare
Authors: Asrinan Asrinan , Dollo Asdar
Published: August 2023

Abstrak

Penelitian ini merupakan penelitian eksperimen (eksperimental) dengan pendekatan kuantitatif. Tujuan utama dalam penelitian ini adalah untuk mendeskripsikan efektifitas penggunaan metode problem solving efektif dalam meningkatkan hasil belajar siswa kelas VII SMP Negeri 5 Parepare. Populasi dalam penelitian ini adalah seluruh Siswa Kelas VII SMP Negeri 5 Parepare yang tersebar dalam 6 kelas parallel. Sedangkan sampel pada penelitian ini diambil dengan menggunakan teknik claster random sampling. Sampel yang digunakan dalam penelitian ini adalah siswa kelas VII A yang berjumlah 23 siswa dan VII B yang berjumlah 23 siswa tahun ajaran 2021/2022. Instrumen dalam penelitian ini berupa tes hasil belajar matematika. Data dianalisis dengan uji Prasyarat yang terdiri atas uji normalitas dan uji homogenitas data. Sedangkan pengujian hipotesisnya menggunakan uji T Independent Sample T-test. Hasil penelitian yang diperoleh adalah: 1) hasil pretest untuk kelas eksperimen diperoleh nilai rata-rata yaitu 47,82 dan pada posttest diperoleh nilai rata-rata 78,43; 2) hasil pretest untuk kelas kontrol diperoleh nilai rata-rata yaitu 42,82 dan pada posttest diperoleh nilai rata-rata yaitu 77,56; 3) Dari hasil uji hipotesis dengan menggunakan uji t di peroleh thitung = 1,96 dan diperoleh nilai signifikansi 0,01< 0,05 sehingga H0 ditolak dan H1 diterima. Oleh karena itu disimpulkan bahwa penggunaan metode problem solving efektif dalam meningkatkan hasil belajar matematika siswa kelas VII SMP Negeri 5 Parepare.

Abstract

The experimental design is used in this research with a quantitative approach. The research aimed to describe the Effectiveness of problem-solving methods that effective to improve the learning outcomes of the 7-grade students in SMP Negeri 5 Parepare. The population were all VII grade students of SMP neg 5 Parepare in six parallel classes. Cluster random sampling is used to determine the sample. The samples were 23 students of VII A and 23 students of VII classes in the academic year 2021/2022. the research instrument was a mathematics achievement test. Furthermore, T independent Sample T-Test is used to test the hypothesis. The data is analyzed with normality and homogeneity test. The research found out that 1) the average experimental class pretest score was 47,82 and the post-test was 78,43; 2) the average controlled class pretest score was 42.82 and the post-test was 77,56; 3) based on the hypotheses testing by T-Test, 1,96 score is found, and the significant score was 0,01 < 0.05 which mean the Ho is rejected, and the H1 is accepted which is problem-solving method was effective to improve the learning outcomes of the 7-grade students in SMP Negeri 5 Parepare.
Efektivitas Kahoot Pada Pembelajaran Bunpou Nouryoku Shiken Level 5
Authors: Putri Rahayuningtyas
Published: August 2023

Abstrak

 

Pembelajaran bunpou (tata bahasa) masih sangat jarang lakukan dengan memanfaatkan media pembelajaran yang menyenangkan dan berbasis teknologi. Tujuan penelitian ini mengetahui efektivitas penggunaan media pembelajaran online berupa kahoot terhadap penguasaan bunpou (tata bahasa)  pada mata kuliah nihongo kentei 1. Penelitian ini merupakan penelitian eksperimen. Jenis penelitian menggunakan metode kuantitatif. Populasi penelitian yakni mahasiswa berjumlah 26 orang terbagi dalam dua kelompok yakni kontrol dan eksperimen. Hasil penelitian merupakan nilai kuis materi bunpo (tata bahasa) dengan menggunakan aplikasi kahoot dan tanpa aplikasi kahoot. Nilai rata-rata yang diperoleh kontrol sebanyak 69,8. Kelas eksperimen memperoleh nilai 85,6. Hasil akhir yang didapatkan kahoot efektif digunakan pada kelas eksperimen. Sehingga kesimpulan akhir yang diperoleh adalah kahoot efektif digunakan dalam pembelajaran bunpou (tata bahasa) mata kuliah nihongo kentei 1 pada mahasiswa semester IV. Penelitian lanjutan yang dapat dilakukan pada pembelajaran bahasa Jepang, materi membaca dan mendengarkan dengan  menggunakan media pembelajaran online yang menarik.
Inovasi Pembelajaran pada Pendidikan Anak Usia Dini di Masa Pandemi Covid-19
Authors: Maswati Maswati , Rosmiati Ramli  , Kalbi Jafar  , Sumadin
Published: August 2023

Pandemi COVID-19 saat ini berdampak pada banyak bidang, termasuk ekonomi, kesehatan, masyarakat, dan keamanan, termasuk pendidikan. Dampaknya pada bidang pendidikan adalah penerapan pembelajaran jarak jauh dengan menggunakan media online. Hal ini membutuhkan pemikiran kreatif dan inovatif dari pihak guru ketika memutuskan sistem pembelajaran mana yang akan diterapkan. Tujuan penelitian ini  untuk mendeskripsikan inovasi pembelajaran pada masa pandemi COVID-19 di PAUD Islam Terpadu Parepare. Metode survei yang digunakan adalah  kualitatif yang menggambarkan lokasi survei di PAUD Islam Terpadu Parepare. Pengumpulan data menggunakan teknik observasi, wawancara, dan dokumentasi pelaksanaan inovasi pembelajaran di masa pandemi Covid-19, serta menggunakan teknik triangulasi sumber untuk validasi keabsahan data. Hasil penelitian ini menggambarkan bahwa inovasi pembelajaran di PAUD Islam Terpadu Parepare bertujuan untuk menopang kualitas pembelajaran dan perkembangan siswa. Inovasi yang diterapkan adalah: 1) Inovasi Perencanaan Pembelajaran, 2) Pembelajaran daring via Whatsapp Grup, 3) Pembelajaran daring via Google Classroom atau google kelas, 4) Home visit, 5) Pembelajaran luring dengan system rolling, 6) Evaluasi Perkembangan anak via google form.
Treatment and outcomes of IDH1-mutant gliomas in elderly patients
Authors: Giantini-Larsen Alexandra M. , Abou-Mrad Zaki , Yu Kenny K. , Reiner Anne S. , Bale Tejus A. , Tabar Viviane , Bander Evan D.
Published: August 2023

OBJECTIVE

Isocitrate dehydrogenase (IDH) mutations in both high- and low-grade gliomas are associated with an increase in survival compared with IDH–wild-type (IDHwt) tumors. A rare and understudied population is elderly individuals, ≥ 65 years of age, who have IDH1-R132H–mutant (IDHmt) gliomas. The objective of this paper was to characterize the institutions’ experience with IDHmt gliomas in a patient population ≥ 65 years of age over the last 10 years.

METHODS

A retrospective study of individuals ≥ 65 years of age with IDHmt gliomas treated between 2010 and 2020 at Memorial Sloan Kettering was performed.

RESULTS

Twenty-five patients ≥ 65 years of age underwent resection or biopsy with a diagnosis of IDHmt glioma (52% WHO grade II, 32% WHO grade III, and 16% WHO grade IV). The most common presenting symptoms were seizure (28%) and motor or sensory deficits (24%). On preoperative MRI, 56% of tumors demonstrated contrast enhancement and 44% had no enhancement. Most patients underwent craniotomy for resection (n = 23, 92%), with subtotal resection achieved in the majority (16/23, 69.6%). Postoperative discharge location included home (64%), acute rehabilitation (16%), subacute rehabilitation (8%), and unknown (12%). Most patients received postoperative chemotherapy (72%) and radiation therapy (68%). The 2- and 5-year survival rates for the overall cohort were 83.1% (95% CI 69.3%–99.7%) and 69.7% (95% CI 53.2%–91.3%), respectively, with gross-total resection or near-total resection, contrast enhancement, and WHO grade significantly associated with survival. From the clinical sequencing data, no significant differences were identified between younger and older IDHmt cohorts.

CONCLUSIONS

While IDH mutation in elderly patients may be rare, these patients have favorable survival relative to their IDHwt counterparts. Age at diagnosis should not be used in isolation to suggest a molecular IDHwt status or poor prognosis when guiding patient treatment decisions.
Angiographic cross-filling between inferior petrosal sinuses and alteration of adrenocorticotropic hormone sampling results for tumor localization in Cushing disease
Authors: Martini Michael L. , Ransom R. Chase , Rechberger Julian S. , O’Keeffe Derek , Young William , Atkinson John L. D. , Meyer Fredric B. , Rinaldo Lorenzo , Carlstrom Lucas , Cloft Harry J. , Van Gompel Jamie
Published: August 2023

OBJECTIVE

Inferior petrosal sinus (IPS) sampling (IPSS) is a diagnostic procedure used to guide diagnostic localization of imaging-negative adrenocorticotropic hormone (ACTH)–secreting pituitary microadenomas. However, the efficacy of IPSS has been suboptimal at accurately lateralizing the adenoma, reducing surgical cure rates and leading to unintended pituitary dysfunction due to the added exploration. One rationale for the occasional imprecision is the existence of additional petrosal sinus collateral channels that connect the IPS bilaterally, which may lead to false localization results during sampling. The aim of this study was to explore a potential connection between normal anatomical variation in the angioarchitecture of the IPSs and the ACTH results obtained in subsequent IPSS tests.

METHODS

A retrospective review was performed on all cases between 1998 and 2013 involving patients at a single institution who underwent IPSS for radiographically equivocal pituitary microadenomas. Cases were reviewed for tumor laterality noted on either operative or pathology reports, as well as the presence of angiographic evidence of cross-filling between the sinuses. In addition, ACTH levels from the right and left IPSs were documented at baseline and at 2, 5, and 10 minutes after corticotropin-releasing hormone (CRH) administration. A ratio of the change in ACTH levels measured at the time of maximal response (10 minutes) versus the levels measured at the initial response (2 minutes) was computed for each patient and compared between patients by their angiographic cross-filling status.

RESULTS

There were 41 patients with a histopathologically confirmed right- or left-sided ACTH-secreting pituitary microadenoma who underwent preoperative IPSS. Among these patients, 28 (68%) showed angiographic evidence of cross-filling between the IPSs, and 13 showed no cross-filling. On average, ACTH levels increased by a factor of 3.91 ± 0.77 in the contralateral IPS in patients with angiographic cross-filling, compared with a factor increase of only 1.80 ± 0.27 in patients without cross-filling (p = 0.014). In comparison, ACTH levels increased by a factor of 2.01 ± 0.57 in the ipsilateral IPS in patients with cross-filling, and by 8.78 ± 7.30 in those without cross-filling (p = 0.373).

CONCLUSIONS

The presence of angiographic cross-filling, suggestive of a greater degree of vascular channel networking between the right and left IPS, is a significant factor influencing the measured rates of change of ACTH in IPSS and may impact the specificity of this test to accurately determine microadenoma laterality in the preoperative setting.
Management and outcome predictors of patients with ruptured deep-seated brain arteriovenous malformations
Authors: Sattari Shahab Aldin , Yang Wuyang , Feghali James , Hung Alice , Xu Risheng , Tamargo Rafael J. , Huang Judy
Published: August 2023

OBJECTIVE

Decision-making for the management of ruptured deep-seated brain arteriovenous malformations (bAVMs) is controversial. This study aimed to shed light on the treatment outcomes of patients with ruptured deep-seated bAVMs.

METHODS

Data on bAVM patients were retrieved from the authors’ institutional database, spanning 1990–2021. The outcomes were annual hemorrhage risk (before and after intervention), number of follow-up hemorrhages, bAVM obliteration, poor modified Rankin Scale (mRS) score (i.e., mRS score > 2), worsened mRS score, and mortality. Multivariable Cox and logistic regression analyses were conducted to determine predictors of time-to-event and categorical outcomes, respectively.

RESULTS

Of the 1066 patients in the database with brain bAVM, 177 patients harboring ruptured deep-seated bAVMs were included. The pretreatment annual hemorrhage risk was 8.24%, and the posttreatment risk was lowered to 1.65%. In multivariable Cox regression analysis, a prenidal aneurysm (HR 2.388, 95% CI 1.057–5.398; p = 0.036) was associated with a higher risk of follow-up hemorrhage, while definitive treatment (i.e., either surgery or radiosurgery vs endovascular embolization or conservative management) (HR 0.267, 95% CI 0.118–0.602; p = 0.001) was associated with a lower risk of follow-up hemorrhage. In multivariable logistic regression analysis, Spetzler-Martin grades IV and V (OR 0.404, 95% CI 0.171–0.917; p = 0.033) and brainstem arteriovenous malformation (AVM) (OR 0.325, 95% CI 0.128–0.778; p = 0.014) were associated with lower odds of obliteration, while definitive treatment (OR 8.864, 95% CI 3.604–25.399; p = 0.008) was associated with higher obliteration odds. Controlling for baseline mRS score, cerebellar AVM (OR 0.286, 95% CI 0.098–0.731; p = 0.013) and definitive treatment (OR 0.361, 95% CI 0.160–0.807; p = 0.013) were associated with lower odds of a poor mRS score, and definitive treatment (OR 0.208, 95% CI 0.076–0.553; p = 0.001) was associated with lower odds of a worsened mRS score. Furthermore, smoking (OR 6.068, 95% CI 1.531–25.581; p = 0.01) and definitive treatment (OR 0.101, 95% CI 0.024–0.361; p = 0.007) were associated with higher and lower mortality odds, respectively.

CONCLUSIONS

A definitive treatment strategy seems to be beneficial in achieving higher obliteration and lower hemorrhage rates while decreasing the odds of a poor mRS score, worsened mRS score, and mortality. In this category of patients, prenidal aneurysms warrant treatment, and smoking cessation should be encouraged.
Grade 3 meningioma survival and recurrence outcomes in an international multicenter cohort
Authors: Tosefsky Kira , Rebchuk Alexander D. , Wang Justin Z. , Ellenbogen Yosef , Drexler Richard , Ricklefs Franz L. , Sauvigny Thomas , Schüller Ulrich , Cutler Christopher B. , Lucke-Wold Brandon , Mehkri Yusuf , Lama Sanju , Sutherland Garnette R. , Karsy Michael , Hoh Brian L. , Westphal Manfred , Zadeh Gelareh , Yip Stephen , Makarenko Serge
Published: August 2023

OBJECTIVE

Grade 3 meningioma represents a rare meningioma subtype, for which limited natural history data are available. The objective of this study was to identify demographics and pathologic characteristics, clinical and functional status outcomes, and prognostic factors in an international cohort of grade 3 meningioma patients.

METHODS

Clinical and histopathological data were collected for patients treated at 7 sites across North America and Europe between 1991 and 2022.

RESULTS

A total of 103 patients (54% female, median age 65 [IQR 52, 72] years) were included. Sixty-seven (65%) patients had de novo grade 3 lesions, whereas 29 (28%) had malignant transformations of lower-grade meningiomas. All patients underwent initial resection of their tumor. Patients were followed for a median of 46 (IQR 24, 108) months, during which time there were 65 (73%) recurrences and 50 (49%) deaths. The 5-year overall survival (OS) and progression-free survival (PFS) rates were 66% (95% CI 56%–77%) and 37% (95% CI 28%–48%), respectively. Age ≥ 65 years and male sex were independent predictors of worse OS and PFS in multivariate regression analysis, while postoperative radiotherapy was independently associated with improved OS. Karnofsky Performance Status (KPS) remained stable relative to baseline over 5 years postdiagnosis among participants who were alive at the end of the follow-up period.

CONCLUSIONS

This large multicenter study provides insight into the longitudinal outcomes of grade 3 meningioma, with respect to recurrence, survival, and functional status. This study affirms the survival benefit conferred by radiotherapy in this population and suggests good functional status outcomes for patients surviving to 5 years postoperatively.
The impact of skull thickness on pediatric stereoencephalography electrode implantation and technical considerations
Authors: Desai Ansh , Sharma Akshay , Sundar Swetha J. , Hsieh Jason K. , Kondylis Efstathios , Patel Arpan , Bulacio Juan , Gupta Ajay , Jehi Lara , Bingaman William
Published: August 2023

OBJECTIVE

One consideration in pediatric stereoencephalography (SEEG) is decreased skull thicknesses compared with adults, which may limit traditional bolt-based anchoring of electrodes. The authors aimed to investigate the safety profile, complication rates, and technical adaptations of placing SEEG electrodes in pediatric patients.

METHODS

The authors retrospectively reviewed all patients aged 12 years or younger at the time of SEEG implantation at their institution. Postimplantation CT scans were used to measure skull thickness at the entry point of each SEEG lead. Postimplantation lead accuracy was also assessed.

RESULTS

Fifty-three patients were reviewed. The median skull thickness was 4.1 (interquartile range [IQR] 3.15–5.2) mm. There were 5 total complications: 1 retained bolt fragment, 3 asymptomatic subdural hematomas, and 1 asymptomatic intracranial hemorrhage. Median radial error from the lead target was 3.5 (IQR 2.24–5.25) mm. Linear regression analysis revealed that increasing skull thickness decreased the deviation from the intended target, implying an improved accuracy to target at thicker skull entry points; this trended towards improved accuracy, but did not achieve statistical significance (p = 0.54).

CONCLUSIONS

This study found a 1.9% hardware complication rate and a 9.4% asymptomatic hemorrhage rate. Suturing electrodes to the scalp may represent a reasonable option if there are concerns of young age or a thin skull. These data indicate that invasive SEEG evaluation is safe among patients 12 years old or younger.
Impact of preoperative spinal injections within 30 days of lumbar decompression on surgical outcomes: a matched institutional study
Authors: Flanigan Patrick , Nathani Karim R. , Martini Michael , Michalopoulos Giorgos D. , Chen Selby , Kalani Maziyar , Bydon Mohamad
Published: August 2023

OBJECTIVE

The authors sought to determine how the temporal proximity of lumbar epidural spinal injection prior to surgery impacts clinical outcomes (e.g., 30-day readmission, postoperative complications, CSF leak) in patients undergoing lumbar decompression without fusion.

METHODS

The authors queried their institutional registry to identify patients who underwent elective lumbar decompression for spondylotic pathology between January 2019 and March 2022 at multiple centers within the same hospital network. Patients were divided into groups based on the time between their surgical date and the most recent preoperative spinal injection: group 1, patients with duration < 1 month; group 2, 1–3 months; and group 3, no spinal injection within 3 months. Primary outcomes of interest were the length of hospital stay, postoperative complications, rate of intraoperative CSF leak, and rates of reoperation and hospital readmission. For patients in groups 1 and 2, the authors also recorded the number of injections within 12 months prior to surgery to better understand the effect of multiple recent injections. The independent Student t-test and Pearson’s chi-square test were mainly performed for univariate analyses of the continuous and categorical variables, respectively.

RESULTS

A total of 121 and 283 patients received a spinal injection at < 1 month and 1–3 months prior to surgery, respectively, and were separately matched in a 3:1 ratio with 2562 patients with no history of preoperative spinal injection within 3 months before surgery. Among the matched cohorts, patients who received spinal injections < 1 month before lumbar decompression had significantly higher risks of 30-day complication (7.4% vs 0.8%, OR 9.6, p < 0.001), 30-day readmission (5.8% vs 2.2%, OR 3.5, p = 0.049), and 90-day readmission (9.1% vs 2.8%, OR 3.5, p = 0.003) than patients with no history of spinal injection. However, compared with patients with no history of spinal injection, the patients who received spinal injections 1–3 months before surgery were not at higher risk for postoperative complications or readmission. The CSF leak rates were significantly different between the three patient cohorts (10.7% vs 6.7% vs 4.9% for the < 1 month, 1–3 months, and no injection cohorts, respectively; p = 0.02).

CONCLUSIONS

Lumbar decompression within 1 month of preoperative spinal injection was associated with higher risks of readmission and postoperative complications, including CSF leak. However, with the exception of CSF leak, these risks were no longer observed when spinal injection occurred 1–3 months prior to lumbar decompression.
Selective thoracolumbar fusion in adult spinal deformity double curves with circumferential minimally invasive surgery: 2-year minimum follow-up
Authors: Anand Neel , Robinson Jerry , Chung Andrew , Gendelberg David , Jiménez-Almonte José H. , Kahwaty Sheila , Khandehroo Babak , Walker Corey
Published: August 2023

OBJECTIVE

Selection of the upper instrumented vertebra (UIV) level for adult spinal deformity (ASD) remains controversial. Although selective fusion attempts have been described for fractional curves or adolescent curves, no authors have described selective thoracolumbar fusion performance for ASD with double curves. This study evaluated the clinical impact of selective fusion constructs within the lower thoracic and/or lumbar spine on ASD with double curves.

METHODS

A retrospective review was performed on an ASD (Cobb angle > 20°, sagittal vertical axis [SVA] > 50 mm, and pelvic incidence minus lumbar lordosis mismatch [PI-LL] > 10°) database consisting of 438 patients who underwent correction with circumferential minimally invasive surgery (CMIS) between 2007 and 2020. The inclusion criteria were ASD double curves (lumbar Cobb angle > 35° and thoracic Cobb angle > 30°), 4 or more levels fused, and minimum 2-year follow-up. Analyses were performed on spinopelvic data and clinical outcome scores. Complications were recorded, specifically the need for revision surgery and hardware-related complications.

RESULTS

Twenty-one ASD double curve patients underwent selective correction with a mean ± SD (range) follow-up of 91 ± 43 (24–174) months. A total of 141 levels were fused with a mean of 6.7 ± 1.3 (4–8) levels. T10 was the most proximal and most common UIV (10/21 [48%]). Pelvic fixation was performed in 12 patients (57%). Significant improvements in lumbar Cobb angle, thoracic Cobb angle, coronal balance, lumbar lordosis, thoracic kyphosis, SVA, and PI-LL were achieved. The uninstrumented thoracic spine demonstrated 14.5° of mean coronal correction and a mean increase of 9.4° in kyphosis. Significant improvements in visual analog scale (VAS) and Oswestry Disability Index (ODI) scores were observed. Four patients required revision for the following reasons: 1) superficial wound infection requiring irrigation and debridement; 2) bilateral L5 pars fractures requiring L5–S1 anterior lumbar interbody fusion and pelvic fixation; 3) adjacent-segment degeneration at L5–S1 requiring anterior lumbar interbody fusion and pelvic fixation; and 4) proximal junctional kyphosis requiring revision fusion to include the entire thoracic curve. There were no instances of hardware failure such as rod breakage or screw loosening.

CONCLUSIONS

Selective thoracolumbar fusion with CMIS for ASD double curves can provide significant clinical improvements. Despite limiting fusion constructs to within the lower thoracic and/or lumbar spine, significant correction can be observed in the uninstrumented thoracic curve. The rate of mechanical complications was low, and the 2-year follow-up results suggested that limited fusion constructs are viable options for ASD double curve patients.
Characterization of the influence of spinopelvic parameters on thoracolumbar trauma
Authors: Withrow Joseph S. , Monterey Michael D. , Narro Analisa , Haley Lauren , Martinez Cruz Marco , Budde Bradley , Trimble Duncan , Sheinberg Dallas , Zaragoza Jennifer , Li Wen , Li Zhouxuan , Caridi John , Quinn John C.
Published: August 2023

OBJECTIVE

The current Roussouly classification identifies four groups of “normal” sagittal spine morphology, which has greatly expanded the understanding of normal heterogeneity of the spine. While there has been extensive characterization of the influence of spinopelvic parameters on outcomes after degenerative spine surgery, the influence of spinopelvic parameters on thoracolumbar trauma has yet to be described. The goal of this study was to determine if spinopelvic parameters and global spine morphology influence fracture location, fracture morphology, and rate of neurological deficit in the setting of thoracolumbar trauma.

METHODS

Of 2896 patients reviewed in the authors’ institutional spine database between January 2014 and April 2020 with an ICD-9/10 diagnosis of thoracolumbar trauma, 514 met the inclusion criteria of acute thoracolumbar fracture on CT and visible femoral heads on sagittal CT. Pelvic incidence (PI) was calculated on sagittal CT. Demographic and clinical data including age, sex, BMI, smoking status, concomitant cervical fracture, mechanism of injury, major fracture location, neurological deficit, AO Spine thoracolumbar injury classification, and management type (operative vs nonoperative) were collected. Patients were stratified into high-PI (≥ 50°) and low-PI (< 50°) groups.

RESULTS

Patients with high PI had a lower incidence of fractures in the lower lumbar spine (below L2) compared with patients with low PI (16% vs 8%, p < 0.01). The last lordotic vertebrae were observed between T10 and L4, and of fractures that occurred at these levels, 75% were at the last lordotic vertebrae. Fall from height was the most common cause of neurological deficit, accounting for 47%. Of the patients presenting with a fall from height, AO Spine type B distraction injuries were more common in the high-PI group (41% vs 18%, p = 0.01). Similarly, within the same subgroup, AO Spine type A compression injuries were more common in the low-PI group (73% vs 53%, p = 0.01).

CONCLUSIONS

Spinopelvic parameters and sagittal balance influence the location and morphology of thoracolumbar fractures. Fractures of the thoracolumbar junction are strongly associated with the inflection point, which is defined by sagittal alignment. While the importance of considering sagittal balance is known for decision-making in degenerative spinal pathology, further studies are required to determine if spinopelvic parameters and sagittal balance should play a role in the decision-making for management of thoracolumbar fractures.
Potensi Perluasan Kemitraan Internasional Universitas Hasanuddin dengan Universitas dalam Lingkungan ASEAN
Authors: Perosyah Nasly
Published: August 2023

This study aims to determine the form and effect of partnerships conducted by Hasanuddin University with universities in Southeast Asia. The research method used is a qualitative method where data collection is carried out by conducting in-depth interviews.

The results of this study indicate that the partnership between Hasanuddin University and the University of Malaysia and the University of Thailand includes student and staff exchanges; Symposium; exchange of scientific works; research funding; cooperation in the honey bee industry to cooperation in the fields of marine and fisheries and biotechnology. So far, this collaboration has shown a significant positive impact. What needs to be improved is that in this partnership it is related to the development of human resources both at Hasanuddin University and partner universities in Southeast Asia.

 

 

Penelitian ini bertujuan untuk mengetahui bentuk dan pengaruh kerjasama kemitraan yang dilakukan oleh Universitas Hasanuddin dengan universitas dalam lingkup Asia Tenggara. Metode penelitian yang digunakan adalah metode kulitatif dimana pengumpulan data dilakukan dengan melakukan wawancara mendalam.

Hasil penelitian ini menujukkan bahwa kerjasama kemitraan antara Universitas Hasanuddin dengan Universitas Malaysia dan Universitas Thailand mencakup pertukaran pelajar dan staf; Symposia; pertukaran karya ilmiah; pendanaan penelitian; kerjasama industri lebah madu hingga pada kerjasama dalam bidang kelautan dan perikanan serta bioteknologi. Sejauh ini kerjasama tersebut menunjukkan dampak positif yang signifikan. Adapun yang perlu ditingkatkan adalah dalam kemitraan ini adalah terkait dengan pengembangan sumber daya manusia baik di Universitas Hasanuddin maupun universitas mitra di lingkup Asia Tenggara
Pengaruh Sanksi Uni Eropa Terhadap Rusia Atas Krisis Ukraina
Authors: Massaguni Mahfud , Badu Muhammad Nasir , Sallatu Muhammad Ashry
Published: August 2023

The crisis of Ukraine is one of the hot topics in the international world talks. The cancellation of the signing of the Association Agreement, which is a stage of integration of Ukraine into the EU, resulted in a wave of massive protests from citizens of Ukraine. Representatives of the EU mediating between the Ukrainian government and the protesting parties ultimately resulted in an agreement to oust President Viktor Yanukovych. The deposition of President Viktor Yanukovych, called pro-Russian, resulted in anger on the part of Russia, on the grounds that the elected president of Viktor Yanukovych's successor was a pro-European party. After the election, unarmed armed forces took over the Crimea territory and held a referendum for the territory to join Russia. Russian involvement in this conflict led to the EU sanctioning Russia. This prolonged sanction not only affects Russia, but also against Europe, because basically each side is one of the largest trading partners.

 

 

Krisis Ukraina merupakan salah satu topik hangat dalam perbincangan dunia internasional. Pembatalan penandatanganan Association Agreement, yaitu sebuah tahapan integrasi Ukraina kedalam Uni Eropa, mengakibatkan gelombang protes besar-besaran dari warga Ukraina. Perwakilan Uni Eropa yang menjadi penengah antara pemerintah Ukraina dan para pihak yang melakukan protes, akhirnya menghasilkan kesepakatan untuk melengserkan presiden Viktor Yanukovych. Dilengserkannya Presiden Viktor Yanukovych yang disebut sebagai pro-Rusia, mengakibatkan kemarahan dari pihak Rusia, dengan alasan presiden terpilih pengganti Viktor Yanukovych merupakan pihak yang pro-Eropa. Setelah pemilihan, pasukan bersenjata tanpa identitas mengambil alih wilayah Krimea dan mengadakan referendum agar wilayah tersebut bergabung dengan Rusia. Keterlibatan Rusia dalam konflik ini menyebabkan Uni Eropa memberi sanksi terhadap Rusia. Sanksi berkepanjangan ini tidak hanya berdampak pada Rusia, namun juga terhadap Eropa, karena pada dasarnya masing-masing pihak merupakan salah satu mitra dagang paling besar.
Strategi Preventif Pemerintah Nusa Tenggara Barat dalam Mewujudkan Zero Unprocedural PMI
Authors: Hariani Septi , Rijal Najamuddin Khairur
Published: August 2023

Indonesian migrant workers are the second largest contributor to the country and play a role in several economic sectors. Unfortunately, this is followed by the emergence of cases that harm migrant workers, which are often caused by lack of knowledge, sources of information and the emergence of brokers who end up in cases of sending illegal migrant workers or often called PMI Unprocedural. The emergence of various modes under the pretext of traveling, visiting and worshiping Umrah in order to escape the surveillance and screening of immigration officers. It is known that West Nusa Tenggara Province is the 3rd largest province that sends PMI abroad. This study uses a descriptive type of research. Based on the results of the study, it is known that preventive efforts have been continuously issued by the West Nusa Tenggara regional government to protect the rights and safety of migrant workers from various threats such as human trafficking syndicates, accidents while traveling, violence at work, and protecting workers from non-payment of salaries by employers. , etc. In addition, it is known that the NTB Provincial Government continues to develop in the formation of Desmigratif and Zero Cos to be able to guarantee the rights of CPMI, PMI, and their families.
 
 
Pekerja migran indonesia menjadi penyumbang terbesar kedua negara dan memaninkan peran pada beberapa sektor ekonomi. Namun sayangnya hal ini diikuti oleh munculnya kasus-kasus yang merugikan para pekerja migran, yang sering kali disesbabkan oleh kurangnya pengetahuan, sumber informasi serta munculnya para calo yang berakhir pada kasus pengiriman pekerja migran ilegal atau sering disebut PMI Unprocedural. Munculnya berbagai modus dengan dalih berwisata, berkunjung, dan beribadah umroh untuk dapat lolos dari pengawasan dan penjaringan petugas keimigrasian. Diketahui bahwasanya Provinsi Nusa Tenggara Barat menjadi Provinsi terbesar ke-3 yang mengirimkan PMI ke luar Negeri. Penelitian ini menggunakan jenis penelitian deskriptif. Berdasarkan hasil penelitian, diketahui bahwa Upaya-upaya preventif terus menerus dikeluarkan pemerintah daerah Nusa Tenggara Barat untuk melindungi hak dan keselamatan pekerja migran dari berbagai ancaman seperti sindikat penjualan manusia, kecelakaan saat diperjalanan, kekerasaan saat bekerja, dan melindungi pekerja dari tidak dibayarkannya gaji oleh majikan, dll. Selain diketahui bahwa Pemerintah Provindi NTB terus melakukan pengembangan dalam pembentukan Desmigratif dan Zero Cos untuk dapat menjamin hak para CPMI, PMI, dan keluarganya.
Peran Nasional Rusia Terhadap Konflik Suriah (2015-2020)
Authors: Riezky Riezky Poetra , Purnama Chandra , Dermawan Windy
Published: August 2023

The ongoing conflict in Syria has led Russia to become more deeply involved in supporting the regime of Bashar Al-Assad. Russia has been the main supporter of the Assad regime since the beginning of the conflict. Russia's participation in the Syrian conflict has prevented Assad from the threat of regime collapse. This research aims to recognize the Russia's national role conceptions in the Syrian conflict. In analyzing, the researcher uses Kalevi J. Holsti's national role conceptions to identify the Russia's national roles. The method used in this research is descriptive qualitative. This research indicates that Russia has the role of faithful ally in the Syrian conflict. It was identified through the decisions, commitments, rules and actions implemented by Russia during the Syrian conflict. Russia's general policy behavior indicates that the historical relationship between the two nations is an important part of Russia's foreign policy. As a faithful ally, Russia has considered Syria as one of its foreign policy concerns, especially in the Middle East.
 
Konflik berkepanjangan yang terjadi di Suriah telah mendorong Rusia untuk terlibat lebih jauh dalam mendukung eksistensi rezim Bashar Al-Assad. Sejak mulai pecahnya konflik, Rusia telah menjadi pendukung utama dari rezim Assad. Partisipasi aktif Rusia dalam konflik Suriah telah menghindarkan Assad dari ancaman kejatuhan rezim. Penelitian ini bertujuan untuk mengidentifikasi konsepsi peran nasional Rusia dalam keterlibatannya terhadap konflik di Suriah. Dalam menganalisis, peneliti menggunakan konsepsi peran nasional Kalevi J. Holsti untuk mengidentifikasi tipe peran nasional yang dijalankan Rusia. Adapun metode yang digunakan dalam penelitian ini adalah kualitatif deskriptif. Penelitian ini menunjukkan  bahwa konsepsi peran nasional yang dijalankan oleh Rusia terhadap konflik di Suriah adalah konsepsi peran nasional dengan tipe sekutu setia. Hal ini terindentifikasi dari keputusan, komitmen, aturan dan tindakan yang dijalankan oleh Rusia selama konflik Suriah berlangsung. Perilaku Rusia secara umum menunjukkan bahwa sejarah panjang hubungan kedua negara tidak dapat dilepaskan dari kebijakan luar negeri Rusia. Sebagai sekutu setia Rusia menjadikan Suriah salah satu pertimbangan dalam menjalankan kebijakan luar negerinya, khususnya di kawasan Timur-Tengah.
Plant What You Eat: Politik Keseharian Komunitas Urban Farming Makassar dalam Merespon Permasalahan Global Terkait Krisis Pangan
Authors: Baharuddin Aswin , Rahmatia Rahmatia , Rusmin Julia Hardianti , Islami Femi Nur
Published: August 2023

The food crisis is a global issue that is increasingly concerning and requires more attention from various countries. One solution to this problem is to apply the concept of Urban Farming in urban areas. The food crisis that occurred was inseparable from the decreasing available agricultural land as a result of the conversion of land functions into residential areas. The city of Makassar is one of the cities with an agricultural area that continues to decrease so that to meet the food needs of the Makassar city population, it is necessary to distribute food from villages to cities which of course causes a decrease in food quality. Responding to this issue, the Urban Farming community in the city of Makassar is trying to invite the community to be involved in Urban Farming activities. The Makassar Gardening Community is one of the active communities in addressing this issue by implementing the Plant What You Eat concept. This study analyzes the activities carried out by the Makassar Gardening Community using the Daily Politics approach. This study found that the daily politics of the Makassar Gardening Community were implemented through forming collective action, encouraging public political participation and building local, national and international networks.
 
Krisis pangan merupakan isu global yang semakin memprihatinkan dan memerlukan perhatian lebih dari berbagai negara. Salah satu solusi dari masalah ini yaitu dengan menerapkan konsep Urban Farming di wilayah perkotaan. Krisis pangan yang terjadi tidak terlepas dari semakin berkurangnya lahan pertanian yang tersedia akibat dari peralihan fungsi lahan menjadi daerah pemukimanan. Kota Makassar merupakan salah satu kota dengan luas wilayah pertanian yang terus mengalami penurunan sehingga untuk memenuhi kebutuhan pangan penduduk kota Makassar, perlu dilakukan distribusi bahan pangan dari desa ke kota yang tentunya menyebabkan turunnya kualitas pangan. Menyikapi isu ini, komunitas Urban Farming yang ada di kota Makassar berupaya untuk mengajak masyarakat untuk terlibat dalam aktivitas Urban Farming. Komunitas Makassar Berkebun merupakan salah satu komunitas yang aktif dalam menyikapi isu ini dengan menerapkan konsep Plant What You Eat. Penelitian ini menganalisis aktivitas yang dilakukan oleh Komunitas Makassar Berkebun dengan menggunakan pendekatan Politik Keseharian. Penelitian ini menemukan bahwa politik keseharian Komunitas Makassar Berkebun diimplementasikan melalui membentuk aksi kolektif, mendorong partisipasi politik public dan membangun jejaring lokal, nasional dan internasional
Critical Discourse Analysis on Islam Nusantara in Indonesia's Foreign Policy
Authors: Nursita Rizki Dian
Published: August 2023

The concept of Islam Nusantara is a concept and perspective of Islam that Nahdlatul Ulama promoted at the NU Congress in 2015. It is used to mention the indigenization of Islamic practice in Indonesia, often contrasted with Arabization. The discourse of Islam Nusantara which is developing well among the government, Islamic organizations, and the community is aging several pros and cons for Indonesia's domestic politics. Furthermore, Islam Nusantara is also often used as the trademark of Indonesia's foreign policy with countries in the Middle East. This study tries to explain how Islam Nusantara Islam as a discourse has been applied in Indonesia's foreign policy towards countries in the Middle East. The study primarily relies on a critical discourse analysis method.
SISTEM INFORMASI PENGGAJIAN PEGAWAI BERBASIS WEBSITE DI APOTEK EMILIA JAKARTA
Authors: Muliani Indah , Islami Nisa Salma , Widiyawati Ratu , Heriyanto
Published: August 2023

Permasalahan yang timbul di Apotek Emilia Jakarta adalah masalah penggajian pegawai, hal ini dikarenakan adanya keragaman perhitungan gaji yang berbeda pada setiap pegawai. Absensi yang dilakukan masih terhitung manual dengan cara foto ditempat lalu dikirimkan via whatsapp kepada admin sehingga admin harus merekap absensi foto karyawan setiap harinya selama satu bulan periode gaji, hal ini tidak efektif karena menyulitkan admin dalam proses perekapan data sehingga memungkinkan terjadinya human error atau kesalahan penulisan dan duplikasi data. Melihat kesulitan yang dihadapi Apotek Emilia Jakarta, membuat penulis menginisiasi program pembuatan sistem informasi penggajian pegawai yang terintegrasi dengan absen online via website. Dimana pada program ini admin tidak perlu lagi repot merekap daftar absensi harian karena dengan absen online pegawai akan melakukan absensi secara mandiri dengan mobile via website kemudian data akan terekam secara otomatis oleh sistem sehingga memudahkan admin dalam merekapitulasi data daftar hadir pegawai dan data perhitungan gaji pegawai dapat dilakukan dengan cepat dan tepat.
Development of the composition and technology of an orodispersible film with melatonin and magnesium citrate
Authors: Butkevych Tetiana , Polova Zhanna , Savchenko Sofia
Published: August 2023

sleep disorders are one of the most common problems among the population today. Numerous scientific publications indicate the effectiveness and safety of melatonin and magnesium use as active ingredients in medicinal products in older adults with sleep disorders. The technological development of an oromucosal preparation – an orodispersible film with melatonin and magnesium citrate is relevant in view of the possibility of increasing the patients’ compliance, those who find it difficult to take oral dosage forms (tablets, capsules) due to possible hand tremors and swallowing disorders. The aim of the study was to develop orodispersible films’ with melatonin and magnesium citrate formulations of various compositions, to conduct a comparative study of their technological parameters in order to select the optimal composition of excipients. The orodispersible films were made by solvent casting method. Melatonin and magnesium citrate were combined with representatives of 6 excipients groups (hydrophilic polymers: agar-agar, xanthan gum, sodium alginate, carboxymethyl cellulose, hydroxypropyl methyl cellulose E3, plasticisers: macrogol 400, glycerol and propylene glycol, saliva stimulants: ascorbic, lactic and citric acids, disintegrant: sodium croscarmellose, sweeteners: sorbitol, erythrol and sucralose, solvent: purified water). Formulations of 9 experimental samples were formed. The prepared solutions were filled into appropriate Petri dishes and dried in several steps. The technological parameters of the dried and cut into 2×3.5 cm orodispersible films were determined: appearance and surface characteristics, average weight and it`s uniformity, area and film thickness, folding endurance, in-vitro disintegration time, and physico-chemical parameter: surface pH value. Formulation No. 5, when dried at 60 ⁰C for 3 hours and 60 ⁰C for 3 hours / 40 ⁰C for 2 hours, and left for congealing for 24 hours at 25±2 ⁰C, formed dry to the touch, durable elastic transparent orodispersible film with very close stable values of parameters (average weight 0.40±0.01 g, area 7 cm2, thickness 0.32±0.05 mm and 0.32±0.03 mm, respectively, folding endurance ˃ 300, pH 6.70±0.04 and 6.74±0.05, respectively, in-vitro disintegration time 32.00±0.67 s and 31.00±0.67 s, respectively). The technology is suitable and it is possible to obtain dry to the touch, durable, elastic transparent films with satisfactory values of the studied parameters under the specified drying conditions.