bluuebunny/crossref_metadata_2025 huggingface dataset:
Laporan Kasus: Penanganan Efek Samping Pseudoefedrin pada Pasien ISPA Anak
Authors: Sari Agata Tika , Indriyanti Niken
Published: May 2022

Abstract

Flu with various symptoms can be caused by infection or allergies. This case report focuses on the management of pseudoephedrine side effects in pediatric ISPA patients receiving polypharmacy therapy. An 8-year-old female patient came to the doctor to practice coughing, colds and fever for 2 days. The patient was then given Puyer containing amoxicillin 200 mg and Puyer for symptomatic symptoms containing paracetamol 200 mg, mebhydrolin napadisylate 50 mg 1/3 tablet, amboroxol 6 mg, dexamethasone 0.5 mg 1/3 tablet, pseudoephedrine HCL 60 mg and triprolidine. HCL 2.5 mg 1/4 tablet with the use of 3×1 for 15 powders. After drinking the powder, the patient complained of heart palpitations.

 

abstrak

flu dengan berbagai gejalanya dapat disebabkan oleh infeksi ataupun alergi. Laporan kasus ini berfokus pada penanganan efek samping pseudoefedrin pada pasien ISPA anak yang mendapatkan terapi polifarmasi. Pasien anak perembuan umur 8 tahun datang ke dokter praktek mengeluhkan batuk, pilek, dan demam sudah 2 hari. Pasien tersebut kemudian diresepkan puyer dengan kandungan amoxicillin 200 mg dan puyer untuk gejala simptomatis  dengan kandungan parasetaml 200 mg, mebhydrolin napadisylate 50 mg 1/3 tablet, ambroxol 6 mg, dexamethasone 0.,5 mg 1/3 tablet, pseudoefedrin HCL 60 mg dan triprolidine HCL 2,5 mg 1/4 tablet dengan aturan pemakaian 3×1 untuk 15 puyer. Setelah minum puyer tersebut pasien mengeluhkan jantung berdebar-debar.
Polimorfisme Gen DRD2 rs1799732 (-141c) Terhadap Terapi Aripiprazole pada Pasien Skizofrenia
Authors: Fitri Fitri , Saleh Irsan , Theodorus Theodorus
Published: May 2022

The polymorphism rs1799732 (-141C) is located in the 5 'promoter region of DRD2, where these SNPs can influence modulation of transcription activity and D2 receptor density. This study aims to provide a literature review of the polymorphism rs1799732 (-141C) because this gene polymorphism is the most common gene polymorphism in the world related to schizophrenia. This gene polymorphism is known to play a role in the variability of response to aripiprazole antipsychotic therapy in schizophrenic patients. The type of review used in this article is in the form of a literature review of 38 literature from various journals and textbooks. Schizophrenia is a disease that can affect the brain. In the brain there is a chemical delivery of messages that will forward messages around the brain. In schizophrenic patients, dopamine is excessive, while dopamine levels play an important role in feelings of pleasure and experiences of different moods. If dopamine levels are imbalanced, sufferers can experience both positive and negative symptoms. The hypothesis states that excessive dopaminergic activity can lead to schizophrenia. The dopaminergic system plays an important role as a modulator of affective and cognitive functions. Dopamine D2 receptor polymorphism is known to be a risk factor for schizophrenia. Polymorphisms are determinants of clinical symptoms and can play a role in the effectiveness and side effects of antipsychotics, including aripiprazole. Aripiprazole is a second-generation antipsychotic, an antipsychotic with partial agonist activity against dopamine D2.
Distribusi Ameloblastoma Berdasarkan Usia, Jenis Kelamin, Lokasi dan Subtipe Histopatologi di RSUD A.W. Sjahranie Samarinda Tahun 2015-2020
Authors: Prinadira Sarah , Pramasari Cristiani Nadya , Samad Syahril
Published: May 2022

Ameloblastoma is one of the most common benign tumors of the oral cavity originating from odontogenic epithelium. This tumor is slow-growing but aggressive, locally invasive, has a high potential for recurrence, transforms into malignant and metastasizes. Risk factors such as tumor location, tumor size, patient age, radiographic appearance, a histopathology subtype, and selection of appropriate treatment correlate with recurrence in ameloblastoma. This study aimed to determine the distribution of ameloblastoma based on age, gender, location, and histopathology subtype. This research is quantitative research with a descriptive method using medical record data subjects and paraffin slides/blocks based on predetermined inclusion criteria. Data were grouped by age, gender, location and histopathology subtype. The results are presented in the form of tables and narratives. Based on the data obtained from 27 samples in this study, the age range category of 45-54 years was the age group with the most ameloblastoma found in 11 patients (40.74%). The number of males patients was 13 patients (48.15%) and 14 patients (51.95%) found on females. Most ameloblastomas were found in the mandible, with a total of 26 patients (96.30%). The most common histopathology subtypes were follicular and plexiform histopathology subtypes with 8 patients (29.63%) each.
Hubungan Kadar Hemoglobin Sebelum Operasi dengan Kebutuhan Transfusi Sel Darah Merah Intra Operasi pada Pasien Bedah Pintas Arteri Koroner di RSUD Abdul Wahab Sjahranie Samarinda
Authors: Rusydi Muhammad Akbar Rizqullah , Tua Ivan Joalsen Manggara , Magdaleni Agustina Rahayu
Published: May 2022

Coronary Artery Bypass Graft (CABG) is a surgical procedure used to create bypass around the blocked coronary artery). Packed Red Cell (PRC) is required during CABG to balance hemoglobin level and the amount of red blood cell tranfused is basically estimated by observing preoperative hemoglobin level. Based on these reasons, the researcher aims to find the correlation between preoperative hemoglobin level and intraoperative red blood cell transfusion. The observational analytical design using cross sectional method was applied.  The purposive non-probability sampling was used to select the research samples. Thirty-five samples fulfilling the inclusive and exclusive criteria were obtained. The findings revealed that patients’ preoperative hemoglobin level was normally transfused with 0 – 249 cc red blood cell for 18 intraoperative patients (51.4%). Patients’ preoperative hemoglobin level  normally transfused with 250 – 500 cc red blood cell was only five patients (14.3%). The abnormally preoperative hemoglobin level transfused with 250 – 500 cc red blood cell was for 10 intraoperative patients (28.6%), whereas the abnormally preopreative hemoglobin level transfused with 0 – 249 cc red blood cell was only two patients (5.7%). It can be concluded that there is a correlation between preoperative hemoglobin level and intraoperative red blood cell transfusion with p value = 0.000 (p <0,05).
Sustainability of early childhood education inspired by the Reggio Emilia Approach during the emergency times: A phenomenographic research
Authors: İNAN Hatice
Published: May 2022

Distance/online education has been an important solution to ensure the continuity of education during the pandemic. The current research utilized the phenomenographic analysis to explore experiences of 260 Reggio Emilia-inspired early childhood educators in Turkey on their online/distance educational practices during the lockdown. The findings showed that only %35 of the educators was able to do either synchronous online education or distance education inspired by Reggio Emilia philosophy. Some of them tried to do distance education more similar to the Reggio Emilia preschools in Italy while some could not do anything at all. While they were asked about what online/distance education inspired by Reggio Emilia should include, they stated the following features: Hands-on, inquiry-based, parent-involved, rich home environment, nature/outdoor-involved, small group work, interactive, interest-based, need-based, and homework-based. However, it is understood from their experiences that they do more synchronized online education instead of other ways of distance education or distance learning, which is emphasized more in Reggio Emilia's philosophy. The results show how dramatic the situation is for the sustainability of early childhood education inspired by Reggio Emilia during the pandemic, as only 91 participants out of 260 Reggio Emilia-inspired educators remained inspired by Reggio Emilia during the closure. They stated on which subject they should receive in-service training.
Adaptation of new variants: A game changer in the evolution of SARS-CoV-2
Authors: Paneri Manita , Saini Ram Gopal
Published: May 2022

The World Health Organization classified Omicron and Delta variants as “variants of concern” because these variants stand as a warning that the epidemic is far from ended. Because of the pandemic’s vast population size, long incubation period, and the diversity of environment, novel variants have been introduced into SARS-CoV-2 genome all over the world. The ability of virus to develop under selection pressure is aided by protective immune system of the host body. The environment of host body shapes its genetic fitness, dispersion, and evolution. Emerging viruses have used recombination and reassortment to create novel antigenic combinations that may enhance the process of cross-species dispersion. The tracking of SARS-CoV-2 genetic variants over time may aid in our knowledge of viral evolution, behavior, and infection trajectory.
The Design and Synthesis of Versatile Molecular Building Blocks: Working Towards the Controlled Self-Assembly of Novel Functional Materials
Authors: Pilkington Melanie , Decurtins Silvio
Published: May 2022

Our research goals are focused on the preparation of novel molecule-based materials that possess specifically designed properties in solution or in the solid state e.g. self-assembly, magnetism, conductivity and spin crossover phenomena. Most of our systems incorporate paramagnetic
transition metal ions and the search for new molecule-based magnetic materials is a prominent theme. Specific areas of research include the preparation and study of oxalate based 2D and 3D magnets, probing the versatility of octacyanometalate building blocks as precursors for new molecular
magnets, and the preparation of new tetrathiafulvalene (TIF) derivatives for applications in molecular and supramolecular chemistry.
Crystal Chemistry and Crystal Growth of Optical Materials
Authors: Hulliger Jürg
Published: May 2022

Crystal chemistry and crystal growth are prior to any detailed investigation of a material that is expected to show interesting linear and nonlinear optical properties. Here, we report on (i) the possibility of exploring the luminescence and optical hole burning properties of Sm2+ in oxide lattices, and (ii) laser frequency shifting crystals showing stimulated Raman scattering (SRS) effects.
Electronic and Molecular Structure of Transition Metal Complexes
Authors: Tregenna-Piggott Philip L.W.
Published: May 2022

The work of the group is centred on the interplay between the electronic and molecular structure of transition metal complexes. Current projects address the role of Jahn-Teller coupling in determining the structural and magnetic properties of complexes with anisotropic ligands such
as water and imidazole. We seek to demonstrate that in order to obtain a satisfactory understanding of metal–water and metal–imidazole interactions, which are central to the functionality of the majority of biological systems, both the electronic and vibrational co-ordinates of
the system must be considered.
On DNA
Authors: Hunziker Jürg
Published: May 2022

The study of oligonucleotide analogs today is mainly targeted at therapeutic or diagnostic applications. However, the detailed knowledge of the structural features of such analogs in comparison to natural DNA may in the future also lead to novel structural design principles in supramolecular
chemistry and materials research.
Arts and Sciences. A Personal Perspective of Tibetan Painting
Authors: Ernst Richard R.
Published: May 2022

The relationship between the arts and the sciences is discussed from the standpoint of a scientist and passionate art lover. The two playgrounds of human creativity have much in common and have cross-fertilized each other over centuries. An active involvement in an artistic discipline
can stimulate scientific creativity by direct analogy and by emotional and intellectual experience. The excitement of a scientist for the arts is exemplified by the author's adventures in Tibetan painting. The scientific study of Tibetan thangkas is discussed by examples from the author's
collection. The analysis of pigments and the dating of the paintings are covered. In addition, some background information on the historical and iconographic context is given.
Archaeometry – Analyzing the Cultural Heritage
Authors: Stern Willem B.
Published: May 2022

Archaeometry is an interdisciplinary field of research, where the studied object stems from archaeological, cultural or historical domains whereas the approach of investigation is based on (natural) science. In the present overview the main focus is on case studies and non-destructive
techniques. X-ray fluorescence and diffraction studies on ceramics, coin alloys, glass, man-made and natural gemstones, and objects of fine art prove that material analysis may contribute to insights in questions of authenticity and origin, but also in ancient technologies e.g. of coinage.
An Odyssey Through Time at EMPA
Authors: Senn Marianne , Devos Wim , Fasnacht Walter , Geiger Thomas , Michel Françoise , Ritter Axel , Fortunato Giuseppino
Published: May 2022

For years EMPA has made many contributions to research on historical materials and their manufacture and conservation in archaeology, restoration and the preservation of historical monuments; areas that are somewhat exotic for a materials testing and research institute. This involves
complex, preferably non-destructive investigations on objects that are often very valuable by means of organic and inorganic analysis methods. The emphasis is on investigations of paints and varnishes on paintings and metals such as gold, silver, copper, bronze and iron. The analysis of various
materials and the associated problems are illustrated by a range of examples.
Ancient Man-made Copper Silicate Pigments Studied by Raman Microscopy
Authors: Bouherour Soraya , Berke Heinz , Wiedemann Hans-Georg
Published: May 2022

This article describes the application of Raman microscopy (micro-Raman spectroscopy) to the characterization and identification of alkaline earth copper silicates, which were used in ancient times as blue and purple pigments and were man-made. Thus, Egyptian Blue (CaCuSi4O10), Chinese Blue (BaCuSi4O10) and Chinese Purple (BaCuSi2O6) give rise to well-defined Raman spectra (excitation 514 nm), which allowed the identification of Egyptian Blue in 11 original Egyptian samples from the VIth Dynasty to Roman times and that of Chinese Purple in six ancient Chinese samples dated from the Warring States period to the Han Dynasty (479 BC to 220 AD). One greenish-blue Egyptian sample turned out not to contain Egyptian Blue but rather a mixture of cupro-wollastonite and libethenite. Some of the Egyptian Blue samples showed only minor admixtures of CaSO4 or silica. Four of the Chinese samples were colour sticks. In one original Chinese stick sample Chinese Blue was recognized as an additional pigment component. One colour stick was revealed to be highly contaminated with Sa-silicates, BaCO3, CaCO3, PbSO4, BaSO4, PbO, and SiO2. The investigated two pigment layer samples of the Terracotta Army, Xi'an, China were analysed by Raman spectroscopy and were found to contain, in addition to Chinese Purple, azurite, vermilion, iron oxide red, PbCO3, PbO, and BaSO4, Chinese Blue was not found.
Konservieren und Restaurieren - ein spurenloser Vorgang?
Authors: Marty Christian
Published: May 2022

Thanks to impulses from the humanities and the natural sciences, the profession of art conservation and restoration has emancipated itself over the past century from its origins as an artisan's craft and established itself as a discipline in its own right. Preserving art and cultural
monuments has ceased to refer only to preserving mere substance. Instead, through these activities, signs and traces of age have for the first time become quite consciously an integral part of an independent, completely new form of value for an object–the value of patina or simply 'the
value of age'. Central to this process was the idea of 'reversibility', a concept employed by experts and laypersons alike as the ultima ratio for preserving an artwork effectively and without damage for future generations utilizing suitable methods and materials. In daily practice,
reversibility has proven to be the ideal rather than the reality. With the realization that any intervention into the substance of an artwork is irreversible, the term 'retreatability' began to be developed in the 1980s. The intention here follows the line of reasoning that restoration measures
on an artwork may no longer be reversible once carried out, but further treatment should be neither hampered nor rendered impossible. However, the contradiction between intervention and preservation is in effect insurmountable because not undertaking an intervention is a decision linked to
a specific time and puts a further historical stamp on a monument or artwork. This means that conservation/restoration itself becomes a new factor in the historical change an artwork undergoes.
Reasoning in ELH w.r.t. General Concept Inclusion Axioms
Authors:   Institut für Theoretische Informatik TU Dresden, Brandt Sebastian
Published: May 2022

In the area of Description Logic (DL) based knowledge representation, research on reasoning w.r.t. general terminologies has mainly focused on very expressive DLs. Recently, though, it was shown for the DL EL, providing only the constructors conjunction and existential restriction, that the subsumption problem w.r.t. cyclic terminologies can be decided in polynomial time, a surprisingly low upper bound. In this paper, we show that even admitting general concept inclusion (GCI) axioms and role hierarchies in EL terminologies preserves the polynomial time upper bound for subsumption. We also show that subsumption becomes co-NP hard when adding one of the constructors number restriction, disjunction, and `allsome', an operator used in the DL k-rep. An interesting implication of the first result is that reasoning over the widely used medical terminology snomed is possible in polynomial time.
A Tableau Algorithm for DLs with Concrete Domains and GCIs
Authors:   Institut für Theoretische Informatik TU Dresden, Lutz Carsten , Miličić Maja ,   Institut für Theoretische Informatik TU Dresden
Published: May 2022

We identify a general property of concrete domains that is sufficient for proving decidability of DLs equipped with them and GCIs. We show that some useful concrete domains, such as temporal one based on the Allen relations and a spatial one based on the RCC-8 relations, have this property. Then, we present a tableau algorithm for reasoning in DLs equipped with such concrete domains.
Improved Methods to Aid Unsupervised Evidence-Based Fact Checking for Online Heath News
Authors: Deka Pritam , Jurek-Loughrey Anna , P. Deepak
Published: May 2022

False information in the domain of online health related articles is of great concern, which has been witnessed abundantly in the current pandemic situation of Covid-19. Recent advancements in the field of Machine Learning and Natural Language Processing can be leveraged to aid people in distinguishing false information from the truth in the domain of online health articles. Whilst there has been substantial progress in this space over the years, research in this area has mainly focused on the sphere of political news. Health fake news is markedly different from fake news in the political context as health information should be evaluated against the most recent and reliable medical resources such as scholarly repositories. However, one of the challenges with such an approach is the retrieval of the pertinent resources. In this work, we formulate two techniques for the retrieval of the most relevant authoritative and reliable medical content from scholarly repositories which can be used to assess veracity of an online health article. The first technique is an unsupervised method of generating queries from claims which are extracted from an online health article. We propose a three-step approach for it and illustrate that our method is able to generate effective queries which can be used for retrieval of information from medical knowledge databases. The second method involves a filtering approach for extracting the most relevant information for the claims. We show how this can be achieved with the help of state of the art transformer models and illustrate it's effectiveness over other methods.
Symmetric states and dynamics of three quantum bits
Authors: Albertini Francesca , D'Alessandro Domenico
Published: May 2022

The unitary group acting on the Hilbert space ${\cal H}:=(C^2)^{\otimes 3}$ of three quantum bits admits a Lie subgroup, $U^{S_3}(8)$, of elements which permute with the symmetric group of permutations of three objects. Under the action of such a Lie subgroup, the Hilbert space ${\cal H}$ splits into three invariant subspaces of dimensions $4$, $2$ and $2$ respectively, each corresponding to an irreducible representation of $su(2)$. The subspace of dimension $4$ is uniquely determined and corresponds to states that are themselves invariant under the action of the symmetric group. This is the so called {\it symmetric sector.} The subspaces of dimension two are not uniquely determined and we parametrize them all. We provide an analysis of pure states that are in the subspaces invariant under $U^{S_3}(8)$. This concerns their entanglement properties, separability criteria and dynamics under the Lie subgroup $U^{S_3}(8)$. As a physical motivation for the states and dynamics we study, we propose a physical set-up which consists of a symmetric network of three spin $\frac{1}{2}$ particles under a common driving electro-magnetic field. {For such system, we solve the control theoretic problem of driving a separable state to a state with maximal distributed entanglement.
On the continuous Zauner conjecture
Authors: Yakymenko Danylo
Published: May 2022

In a recent paper by S. Pandey, V. Paulsen, J. Prakash, and M. Rahaman, the authors studied the entanglement breaking quantum channels $\Phi_t:\mbb{C}^{d\times d} \to \mbb{C}^{d \times d}$ for $t \in [-\frac{1}{d^2-1}, \frac{1}{d+1}]$ defined by $\Phi_t(X) = tX+ (1-t)\tr(X) \frac{1}{d}I$. They proved that Zauner's conjecture is equivalent to the statement that entanglement breaking rank of $\Phi_{\frac{1}{d+1}}$ is $d^2$. The authors made the extended conjecture that $\ebr(\Phi_t)=d^2$ for every $t \in [0, \frac{1}{d+1}]$ and proved it in dimensions 2 and 3. In this paper we prove that for any $t \in [-\frac{1}{d^2-1}, \frac{1}{d+1}] \setminus\{0\}$ the equality $\ebr(\Phi_t)=d^2$ is equivalent to the existence of a pair of informationally-complete unit-norm tight frames $\{|x_i\ra\}_{i=1}^{d^2}, \{|y_i\ra\}_{i=1}^{d^2}$ in $\mbb{C}^d $ which are mutually unbiased in the following sense: for any $i\neq j$ it holds that $|\la x_i|y_j\ra|^2 = \frac{1-t}{d}$ and $|\la x_i|y_i\ra|^2 = \frac{t(d^2-1)+1}{d}$. Moreover, it follows that $|\la x_i|x_j\ra\la y_i|y_j\ra|=|t|$ for $i\neq j$. However, our numerical searches for solutions were not successful in dimensions 4 and 5 for values of $t$ other than $0$ or $\frac{1}{d+1}$.
A thermalized electrokinetics model including stochastic reactions suitable for multiscale simulations of reaction-advection-diffusion systems
Authors: Tischler Ingo , Weik Florian , Kaufmann Robert , Kuron Michael , Weeber Rudolf , Holm Christian
Published: May 2022

We introduce a scheme to simulate the spatial and temporal evolution of the densities of charged species, taking into account diffusion, thermal fluctuations, coupling to a carrier fluid, and chemical reactions. To this end, the diffusive fluxes in the electrokinetic model by Capuani et al. [1] are supplemented with thermal fluctuations. Chemical reactions are included via an additional source term in the mass balance equation. The diffusion-reaction model is then coupled to a solver for fluctuating hydrodynamics based on the lattice Boltzmann method. This combination is particularly useful for soft matter simulations, due to the ability to couple particles to the lattice-Boltzmann fluid. These could, e.g., be charged colloids or polymers, which then interact with an ion distribution. We describe one implementations based on the automatic code generation tools pystencils and lbmpy, and another one that is contained in the molecular dynamics package ESPResSo and that allows for an easy coupling of particles to the density fields. We validate our implementations by comparing to several known analytic results. Our method can be applied to coarse-grained catalysis problems as well as to many other multi-scale problems that require the coupling of explicit-particle simulations to flow fields, diffusion, and reaction problems in arbitrary geometries.
Bypassing Backmapping: Coarse-Grained Electronic Property Distributions Using Heteroscedastic Gaussian Processes
Authors: Maier Charlie , Jackson Nicholas
Published: May 2022

We employ deep kernel learning electronic coarse-graining (DKL-ECG) with approximate Gaussian Processes as a flexible and scalable framework for learning heteroscedastic electronic property distributions as a smooth function of coarse-grained (CG) configuration. The appropriateness of the Gaussian prior on the predictive CG property distributions is justified as a function of CG model resolution by examining the statistics of the target distributions. The certainties of the predictive CG distributions are shown to be limited by CG model resolution, with DKL-ECG predictive noise converging to the intrinsic physical noise induced by the CG mapping operator for multiple chemistries. Further analysis of the resolution dependence of the learned CG property distributions allows for the identification of CG mapping operators that capture CG degrees of freedom with strong electron-phonon coupling. We further demonstrate the ability to construct the exact quantum chemical valence electronic density of states (EDOS), including behavior in the tails of the EDOS, from an entirely CG model by combining iterative boltzmann inversion and DKL-ECG. DKL-ECG provides a means of learning CG distributions of all-atom properties that are traditionally ``lost" in CG model development, introducing a robust methodological alternative to backmapping algorithms commonly employed to recover all-atom property distributions from CG simulations.
Cobalt anti-MXenes as Promising Anode Materials for Sodium-ion Batteries
Authors: Banerjee Subhadeep , Ghosh Kalpak , Reddy Sandeep K , Yamijala Sharma S. R. K. C.
Published: May 2022

The current electric vehicle market is entirely dominated by lithium-ion batteries (LIBs). However, due to the limited and unequal distribution of LIB raw materials on earth, there is a continuous effort to design alternate storage devices. Among the alternatives to LIBs, sodium-ion batteries (NIBs) are at the forefront because sodium resources are ubiquitous worldwide and virtually inexhaustible. However, one of the major drawbacks of the NIBs is their low specific charge capacity. Since the specific charge capacity of a cell can be improved by increasing the specific charge capacity of the anode material, there is a constant effort to find suitable anode materials. Recent studies suggested that cobalt-boride (CoB) anti-MXene material (a newly discovered two-dimensional material) can yield superior specific charge capacities for LIBs than traditional graphite-based anodes. Inspired by these findings, in this work, we considered six cobalt-based anti-MXene materials (Co-anti-MXenes), namely, CoAs, CoB, CoP, CoS, CoSe, and CoSi, and examined their competency as anode materials for NIBs. Our findings suggest that Co-anti-MXenes possess superior specific charge capacities (~ 390–590 mAh/g) than many well-studied anode materials like MoS2 (146 mAh/g), Cr2C (276 mAh/g), expanded graphite (284 mAh/g), etc. Moreover, their greater affinity (-0.55 to -1.16 eV) to Na atoms, along with reasonably small diffusion energy barriers (0.32 to 0.59 eV) and low average sodiation voltages (0.2 to 0.64 V), suggest that these Co-anti-MXenes can serve as excellent anode materials for NIBs.
Direct alpha-Amination of Amides and Lactams Enabled by the (3+2) Vinyl Azide-Enolate Cycloaddition Manifold
Authors: Bell-Tyrer Joseph , Hume Paul , Grant Phillip , Brimble Margaret , Furkert Daniel
Published: May 2022

Direct alpha-amination of carbonyl compounds remains an important yet synthetically challenging transformation. Here we report a solution for direct alpha-amination of amides and lactams, identified through fundamental exploration of (3+2) vinyl azide-enolate cycloaddition chemistry. Initial cycloadducts undergo rearrangement via 1,2-N-migration to afford imine intermediates that are readily converted to the target alpha-amino amides or lactams. The sequence requires no pre-functionalisation, can be performed on a range of substrates, including compound classes unsuccessful using reported methods, and delivers primary or secondary alpha-amines. This work highlights the diversity and synthetic potential of the rapidly expanding (3+2) azide-enolate cycloaddition manifold.
Ene-gamma-lactam synthesis via (3+2) vinyl azide-enolate cycloaddition: Enolate addition to vinyl triazolinone intermediates
Authors: Bell-Tyrer Joseph , Hume Paul , Brimble Margaret , Furkert Daniel
Published: May 2022

Vinyl azides have undergone a recent renaissance as versatile synthetic reagents, however their reactivity as 1,3-dipoles in (3+2) cycloadditions remains underexplored. Here the synthesis of ene-gamma-lactam scaffolds via (3+2) cycloaddition of alpha-substituted vinyl azides with ester enolates is established. Mechanistic investigations, including isolation of reaction intermediates and density functional theory calculations, implicate an unprecedented conjugate-type addition to the exocyclic alkene of an N-vinyl triazolinone intermediate generated in the cycloaddition step. Determination of the reaction scope and application to synthesis of the natural product sargassumlactam is reported.
La informática educativa
Authors: Becerra Oscar
Published: May 2022

El tema que vamos a tratar es la informática educativa, cómo la tecnología puede ayudarnos a crear un nuevo ambiente de aprendizaje.
La Cooperación Técnica Internacional.
Authors: Bernuy Morales Soledad
Published: May 2022

No presenta resumen.
Importancia de la informática en la gestión del ingeniero industrial
Authors: Núñez Ponce Roxana
Published: May 2022

La Ing. Núñez nos expone de manera muy clara el por qué un Ingeniero Industrial debe estar capacitado para utilizar la informática para el logro de beneficios a favor de la empresa.
Círculos de Calidad Total
Authors: Palacios  C. José
Published: May 2022

La iniciativa que expone el autor del artículo, de formar los "Círculos de Calidad" integrados por los trabajadores de la empresa, es muy importante  pues permite la participación directa del personal que trabaja en la producción y que tiene la oportunidad de observar el proceso total  de elaboración y de la calidad del producto terminado.
El rol de la fermentación en la producción de galletas tipo soda
Authors: Villanueva Flores Rafael
Published: May 2022

El lector descubrirá en el presente artículo, varios secretos sumamente interesantes, en la elaboración de las galletas de soda.
Energización : una alternativa para el desarrollo rural
Authors: Oliveros D. Alfredo
Published: May 2022

En este trabajo se presenta un procedimiento alternativo a la práctica tradicional que utilizan las empresas para la electrificación rural en nuestro país.
La patente como instrumento de información tecnológica
Authors: Combe de Vertiz Olga
Published: May 2022

No presenta resumen.
Física nuclear & de partículas : "Modelos nucleares"
Authors: Ordonez Ortiz Manuel J.
Published: May 2022

El presente trabajo trata sobre los modelos nucleares que fueron ideados en sus comienzos para poder analizar el comportamiento y la estructura del núcleo.
Ingeniería industrial ¿Total?
Authors: Barcelli G. Guillermo
Published: May 2022

No presenta resumen.
Las nuevas realidades y la ingeniería industrial
Authors: Jarufe Zedán Benjamín
Published: May 2022

No presenta resumen.
Administración de la energía
Authors: Fernández Baca Marco
Published: May 2022

No presenta resumen.
Cómo administrar un proyecto de código de barras
Authors: De Las Casas Sommerkamp Javier
Published: May 2022

No presenta resumen.
La producción y los Sistemas de Información
Authors: Wong Campos Pedro
Published: May 2022

No presenta resumen.
El gerente de abastecimiento y su campo de acción en la empresa
Authors: Salas Schwarz Jorge A.
Published: May 2022

No presenta resumen.
El radón y el saneamiento ambiental
Authors: Niezen Menaut Eduardo z.
Published: May 2022

No presenta resumen.
Dirección por objetivos. Aplicaciones en la pequeña empresa
Authors: Gómez Delgado Yolanda
Published: May 2022

No presenta resumen.
Axonal transport of Hrs is activity dependent and facilitates synaptic vesicle protein degradation
Authors: Birdsall Veronica , Kirwan Konner , Zhu Mei , Imoto Yuuta , Wilson Scott M , Watanabe Shigeki , Waites Clarissa L
Published: May 2022

Turnover of synaptic vesicle (SV) proteins is vital for the maintenance of healthy and functional synapses. SV protein turnover is driven by neuronal activity in an endosomal sorting complex required for transport (ESCRT)-dependent manner. Here, we characterize a critical step in this process: axonal transport of ESCRT-0 component Hrs, necessary for sorting proteins into the ESCRT pathway and recruiting downstream ESCRT machinery to catalyze multivesicular body (MVB) formation. We find that neuronal activity stimulates the formation of presynaptic endosomes and MVBs, as well as the motility of Hrs+ vesicles in axons and their delivery to SV pools. Hrs+ vesicles co-transport ESCRT-0 component STAM1 and comprise a subset of Rab5+ vesicles, likely representing pro-degradative early endosomes. Furthermore, we identify kinesin motor protein KIF13A as essential for the activity-dependent transport of Hrs to SV pools and the degradation of SV membrane proteins. Together, these data demonstrate a novel activity- and KIF13A-dependent mechanism for mobilizing axonal transport of ESCRT machinery to facilitate the degradation of SV membrane proteins.
ВЛАСТИВОСТІ І ХАРАКТЕРИСТИКИ ПСИХОЛОГІЧНИХ МЕЖ ОСОБИСТОСТІ В РІЗНІ ПЕРІОДИ ПІДЛІТКОВОГО ВІКУ
Authors: Дорожкін В. Р. , Савченко О. В.
Published: May 2022

Стаття присвячена дослідженню властивостей і характеристик психологічних меж у підлітків. Автори розглядають концепцію, згідно з якою підлітковий вік є сенситивним з точки зору розвитку внутрішніх і зовнішніх Я-відмежуваннь. У тексті аналізуються основні психічні утворення підліткового віку, вивчається їх вплив на зміну психологічних меж підлітків. Стаття складається з теоретичної та емпіричної частин. Емпіричне дослідження підлітків молодшого і старшого віку дозволило уточнити, як зміни функцій і відмежувань Я пов'язані з розвитком особистості підлітків і як цей розвиток, зі свого боку, обумовлює трансформацію й підтримує низку психічних новоутворень підліткового віку. Зокрема, доведено, що в підлітків молодшого і старшого віку відрізняються окремі параметри психологічних меж, їх функції та Я-відмежування. Показано, як за допомогою рефлексії й самосвідомості підлітки вчаться керувати функціями психологічних меж, що призводить до перегляду ціх меж і їх руху. Виявлено, що більший розвиток Я-відмежуваннь у старших підлітків свідчить на користь внутрішньої диференціації психіки, дає змогу утримувати відрефлексовані частини себе й забезпечує підтримку цілої низки новоутворень підліткового віку, таких як становлення самосвідомості та формування стійкої самооцінки. Крім того показано, що функції психологічних меж працюють у підлітків в екстремально протилежних режимах: то в конструктивному, то в дефіцітарному. Саме це пояснює подвійну природу відносин, які створює підліток. На основі виявлених відмінностей можна стверджувати, що підлітковий період розвитку є сенситивним для формування низки функцій психологічних меж, а також зовнішніх і внутрішніх Я-відмежувань. Зміни функцій і відмежувань Я є наслідком розвитку особистості підлітків, але, зі свого боку, вони обумовлюють її трансформацію й підтримують низку психічних новоутворень підліткового віку.
Siyaseti ve Kamuyu Yönetmeye Talip Olmayan Cinsiyet: Bir Çıkarsama
Authors: DEMİREL  DEĞİRMENCİ Songül
Published: May 2022

Toplumsal cinsiyetle ilgili çalışmaların amacı, erkeğe göre dezavantajlı konumda bulunan kadının bu durumunun ortadan kaldırılmasıdır. Bu hedefe ulaşabilmek için devletin desteği gerekmektedir. Günümüz modern demokrasilerinde, karar verenler kimlerdir? Sorunlara vakıf kimselerin temsil edilebilmesi, çözümde kilit noktadır. Bunlar da yönetimin her kademesinde özellikle de karar alma mekanizmalarında kadınların bulunmasından geçmektedir. Oysa kadın ve erkek her iki cinsin meslek tercihlerinde; toplumsal kültürün etkisini bulmak mümkündür. Siyasetçi ve kamu yöneticisi olmanın eğitimle elde edilemeyecek bir liderlik yeteneğini gerektirdiği bir yana; acaba eğitim alarak bu meslekleri edinmek isteyen kişilerin cinsiyetleri nedir? Nitekim karar alma mekanizmalarında kadınların en az erkekler kadar temsil edilmesi tabii bir sonuç olmalıdır. Ancak siyasette ve kamu yönetiminde kadınların temsiline yönelik geçmiş araştırmaların yeterince olmadıklarını kanıtlamaktadır. Cinsiyet ve meslek seçimi arasındaki ilişkinin gözden geçirildiği bu araştırmada, siyaset bilimi ve kamu yönetimi bölümleri öğrenci sayıları üzerinde yapılan incelemeyle söz konusu ilişki doğrulanmaktadır. Böylelikle araştırmanın varsayımı, mesleki ve bilimsel boyutuyla ele alınmaktadır.
Analysis of Energy Consumption in Wireless Body Area Network Usingmac Protocols (baseline And Smac)
Authors: Hussein Rezheen , Ali Ismail
Published: May 2022

Abstract A Wireless Body Area Network (WBAN) is a short-range network that consists of a coordinator and a gathering of low-power sensors that can be embedded in, or attached to the human body. A WBAN can be used for a diversity of new uses which including online health control, home/health care, pharmacy, multimedia, and sports, among many more, all of which take advantage of the unrestricted mobility that WBANs can provide. In the medical industry, for example, a patient may be fitted with a WBAN of sensors that continuously track basic biological functions including temperature, blood pressure, heart rate, electrocardiogram (ECG), breathing, and so on. The patient does not have to lie in bed and can move around freely in the room or even leave the hospital for a short period of time. This increases the patient's feature of life while further lowering treatment costs. Furthermore, evidence gathered over a prolonged period of time and in the patient's natural habitat provides more useful knowledge, allowing for a more definitive and, in some cases, quicker diagnosis. Sensors connected to the human body are normally battery-powered devices with brief lifetimes. Institute of Electrical and Electronics Engineers (IEEE) 802.15.6 standard is the typical choice for low power ingestion and reliable short-range communication for Wireless Body Sensor Networks (WBSNs). The effects are demonstrated using the Omnet++ simulator and its Castalia extension for WBANs
Research on the Fusion Course System Based on Improving Employability Under the Background of Application-Orientated Undergraduate
Authors: Wang Xue , Ma Tiemin , Liu Ling , Yang Yushu , Li Aichuan , Yang Dongfeng , Lin Lihong
Published: May 2022

Facing the development of “Internet +” and the demand of diversified talents in the market, excellent talents with computer operation ability are increasingly needed by all trades and professions. This “ability” added to professional skills will enhance the employment competitiveness to a great extent. Therefore, the traditional employment mode and talent training mode need to be transformed by various integrated means to adapt to the change in employment status. By analyzing the current situation and employment of agricultural application-oriented universities, the fusion course is put forward in this paper, taking the construction of the Office Automation course, a platform course of Heilongjiang Bayi Agricultural University, as an example.
EFL Learners’ Attitude Towards Culture and Cultural Learning
Authors: Yan Mengjiao
Published: May 2022

Language and culture are complementary, helpful, and inspiring to one another. Especially for foreign language learners, culture is extremely important to understand the social and cultural background of the target language. This study aims to explore foreign language learners’ perception towards cultural learning. In order to come to a conclusion, a quantitative method was adopted by distributing questionnaires to 31 Chinese EFL students. From the perspective of Chinese students, culture and cultural learning are crucial in the second language acquisition process.
Studying the Two New Convolutions of Fractional Fourier Transform by Using Dirac Notation
Authors: Cai Ying , Lv Cuihong , Huang Nan , Jin Nan
Published: May 2022

Based on quantum mechanical representation and operator theory, this paper restates the two new convolutions of fractional Fourier transform (FrFT) by making full use of the conversion relationship between two mutual conjugates: coordinate representation and momentum representation. This paper gives full play to the efficiency of Dirac notation and proves the convolutions of fractional Fourier transform from the perspective of quantum optics, a field that has been developing rapidly. These two new convolution methods have potential value in signal processing.
Research on the Optimal Strategy of “Working Together with One Heart” Project
Authors: Cong Jing
Published: May 2022

The “Working Together with One Heart” project, also known as the “One Heart Drum” project, is a collaboration skill development project, which assesses the collaboration skills of its team members. In this paper, the method of combining actual problems with physical model analysis is used to determine the influence of different factors in the project operation, and a geometric analysis model is also established. Through MATLAB simulation and assignment operation, the optimal strategy of the project is finally obtained.
Design and Control Scheme of the Mooring System
Authors: Cong Jing
Published: May 2022

In this paper, by analyzing the design and control scheme of the mooring system based on theoretical mechanics, force analysis is conducted on the buoy, steel pipe, steel drum, and anchor chain, and a reasonable mathematical model is constructed to solve the problems of the inclination angle of the steel drum and each section of the steel pipe, the shape of the anchor chain, the draft of the buoy, and the swimming area under different wind speeds, thus providing a reliable basis for the design of the system.
Three Novel Mutations of APC Gene Found in A Chinese Family with Familial Adenomatous Polyposis
Authors: Gao Shujuan , Lin Min , Jin Yan , Wang Zhuona , Zhu Yunqing , Liu Guisheng , Guo Xueyan
Published: May 2022

Objective: To identify the causative adenomatous polyposis coli (APC) gene defects associated with a pedigree of familial adenomatous polyposis (FAP). Methods: FAP was diagnosed based on clinical manifestations, family history, as well as endoscopic and pathological examinations. The blood samples of the FAP pedigree members, colonic polyp patients, and normal individuals were collected. Genomic DNA was then extracted from those samples.  APC mutation analysis was conducted via direct polymerase chain reaction (PCR) sequencing. Results: Three synonymous mutations and a missense mutation were found: c.5034G>A (p.Gly1678Gly), c.5465T>A (p.Val1822Asp), c.5880G>A (p.Pro1960Pro), and c.5274T>G (p.Ser1758Ser). Among them, the homozygous mutation on APC gene c.5034G>A has been reported, while the other three mutations have not been reported in the Chinese Han population. Individuals with c.5465T>A (p.Val1822ASP) missense mutation eventually suffer from colon cancer and have poor prognosis. We found no mutation in patients with simple intestinal polyp and in normal individuals. In addition, there were homozygous and heterozygous mutations in different patients from the same family. Conclusion: Three new mutations of APC gene were firstly reported in Han population. The missense mutation of c.5465T>A (p.Val1822Asp) may be the cause of carcinogenesis in this FAP pedigree with poor prognosis.
Research on the Application of Computer Network Technology in Electronic Information Engineering
Authors: Cui Zhiwu
Published: May 2022

Computer network technology has a very important role in electronic information engineering. The application of this technology not only enriches the traditional information engineering functions, but also effectively guarantees the efficiency and quality. At present, due to the wide variety of external information that Chinese citizens are exposed to, in addition to the variegated and mixed content, it is easy for information to be leaked or stolen. In order to avoid similar situations, it is necessary for people to pay more attention to network system security, so as to ensure that the quality of life of citizens can be guaranteed. In view of that, this paper discusses and analyzes the application of computer network technology in electronic information engineering.
Application of Green Design Concept in Interior Design Practice
Authors: Han Xiao
Published: May 2022

Parallel with the increasing development of China’s social economy, many people are paying attention to the high-level design quality of interior design and the aesthetics and environmental protection of interior design. Therefore, the concept of integrating green design has become the focus of designers in the works of interior design. Based on the overview of green interior design concept, the author introduces the role and principles of green design concept in interior design, and discusses in detail the key applications of green design concept in interior design, hoping to provide reference and guidance for interior design practitioners.
Research on the Integration of Structural Design and Material Parameters of Long-life Asphalt Pavement
Authors: Shen Yongjun
Published: May 2022

In order to reduce the disease risk stemming from asphalt concrete pavement and ensure the safety of road operation, we should pay attention to the structural design of long-life asphalt pavement, strengthen the selection of long-term pavement materials, scientifically set the pavement mechanical performance indexes based on the calculation results of pavement structure thickness combination and modulus combination, and ensure the stability and durability of road pavement structure through the real-time establishment of three-dimensional finite element calculation model, as well as the integrated design that takes into consideration the aspects of road subgrade, semi-rigid base and asphalt layer.
Research Progress of Traditional Chinese and Western Medicine in Hyperthyroid Heart Disease
Authors: Li Shuyu , Zhao Mingjun
Published: May 2022

In recent years, hyperthyroid heart disease has become a condition with high incidence rate and high mortality rate. This paper discusses the pathogenesis, treatment, and influencing factors of hyperthyroid heart disease from two different angles – traditional Chinese medicine and western medicine – in hope to provide a reference basis for the treatment of hyperthyroid heart disease.