bluuebunny/crossref_metadata_2025 huggingface dataset:
Rationalizing mineral gypsum through microbially enriched municipal solid waste compost for amelioration and regaining productivity potential of degraded sodic soils
Authors: Singh Yash Pal , Arora Sanjay , Mishra Vinay Kumar , Singh Atul Kumar
Published: January 2023

Reclamation of alkali soils to harness their productivity potential is more complex due to presence excessive sodium ions, poor hydraulic conductivity and infiltration rate, resulting in poor plant growth and crop productivity. Sodic soil reclamation using inorganic ameliorants like mineral gypsum or phosphogypsum is beyond the reach of small and marginal farmers having alkali soils because of their higher market prices and shortage of availability. Conjoint use of inorganic and organic amendments can be a pragmatic solution for improving soil physico-chemical and biological properties and sustaining crop productivity. Municipal solid waste compost (MSWC) available in abundant quantity if enriched with efficient halophilic microbial consortium and used in conjunction with reduced dose of gypsum can be a cost effective approach for sustainable reclamation of alkali soils and harnessing their productivity potential. Hence, a field experiment was conducted on a highly alkali soil (pH29.2 ± 0.10), electrical conductivity (EC) 114 µSm− 1±12.0, exchangeable sodium percentage 48 ± 2.50 and organic carbon (0.30%) was conducted during 2018-19 to 2020-21 to study the combined effect inorganic and organic (enriched municipal solid waste compost (EMSWC) amendments on amelioration of alkali soils and sustaining productivity of rice-wheat cropping system. Application of reduced dose of gypsum (25% GR) in conjunction with EMSWC @ 10 t ha− 1(T6) showed significant improvement in soil physico-chemical and biological properties over the sole application of organic (T3& T4), inorganic (T2) and control (T1). A significant improvement in soil fertility status in terms of available nitrogen and micronutrients as well as CO3,HCO3, Cl, Ca and Mg content were recorded with the combined application of organic and inorganic soil amendments (T5& T6) over the sole application of mineral gypsum. Soil microbial biomass carbon (MBC), nitrogen (MBN) and phosphorus (MBP) improved significantly due to application of EMSWC with gypsum over the application of gypsum only. Grain yield of rice and wheat increased significantly (P < 0.05) owing to the application of reduced dose of gypsum (25% GR) and EMSWC @10 t ha− 1(T6) with values of 5.55 and 3.83 t ha− 1, respectively over rest of the treatments. Three years economic analysis of the study revealed that the treatment T6and T5gave highest positive net return whereas it was lowest in treatment T1and negative in treatment T2. The highest benefit to cost ratio (B:C) were obtained in treatment T6and T5which were significantly higher compared to rest of the treatments.
Necroptosis Drives Major Adverse Cardiovascular Events During Severe COVID-19
Authors: Wiscovitch-Russo Rosana , Ibáñez-Prada Elsa D. , Serrano-Mayorga Cristian C. , Sievers Benjamin L. , Engelbride Maeve A. , Padmanabhan Surya , Tan Gene S. , Vashee Sanjay , Bustos Ingrid G. , Pachecho Carlos , Mendez Lina , Dube Peter H. , Singh Harinder , Reyes Luis Felipe , Gonzalez-Juarbe Norberto
Published: January 2023

Background

The mechanisms used by SARS-CoV-2 to induce major adverse cardiac events (MACE) are unknown. Thus, we aimed to determine if SARS-CoV-2 can infect the heart to kill cardiomyocytes and induce MACE in patients with severe COVID-19.

Methods

This observational prospective cohort study includes experiments with hamsters and human samples from patients with severe COVID-19. Cytokines and serum biomarkers were analyzed in human serum. Cardiac transcriptome analyses were performed in hamsters' hearts.

Results

From a cohort of 70 patients, MACE was documented in 26% (18/70). Those who developed MACE had higher Log copies/mL of SARS-CoV-2, troponin-I, and pro-BNP in serum. Also, the elevation of IP-10 and a major decrease in levels of IL-17ɑ, IL-6, and IL-1rɑ were observed. No differences were found in the ability of serum antibodies to neutralize viral spike proteins in pseudoviruses from variants of concern. In hamster models, we found a stark increase in viral titers in the hearts 4 days post-infection. The cardiac transcriptome evaluation resulted in the differential expression of ~ 9% of the total transcripts. Analysis of transcriptional changes of the effectors of necroptosis (mixed lineage kinase domain-like, MLKL) and pyroptosis (gasdermin D) showed necroptosis, but not pyroptosis, to be elevated. Active form of MLKL (phosphorylated MLKL, pMLKL) was elevated in hamster hearts and, most importantly, in the serum of MACE patients.

Conclusion

SARS-CoV-2 can reach the heart during severe COVID-19 and induce necroptosis in the heart of patients with MACE. Thus, pMLKL could be used as a biomarker of cardiac damage and a therapeutic target.

Trial registration: Not applicable.
Reduced urine pregnenolone concentration after clinical response in patients with depression: an open-label prospective longitudinal study
Authors: Pedraz-Petrozzi Bruno , Lamade Eva , Petry Rebekka , Scharnholz Barbara , Vítků Jana , Hill Martin , Stárka Ľuboslav , Gilles Maria , Deuschle Michael
Published: January 2023

Background
Identifying biological alterations in patients with depression, particularly those that differ between responders and non-responders, is of interest to clinical practice. Biomarker candidates involve neurosteroids, including pregnenolone (PREG) and allopregnanolone (ALLO). However, alterations in neurosteroids associated with treatment response are understudied. This study's main aim was to evaluate the effects of antidepressant treatment, clinical response, and treatment duration on neurosteroids PREG and ALLO in depression.
Materials and Methods
In a 4-week, open-label trial, participants were allocated randomly to the venlafaxine (n = 27) or mirtazapine (n = 30) group. Urine concentrations of PREG and ALLO were assessed through gas chromatography-mass spectrometry. Participants collected night urine between 10:30 p.m. and 8:00 a.m. The primary outcome was the effect of treatment (mirtazapine or venlafaxine), clinical response (operationalized through the Hamilton Depression Rating Scale), and time (baseline compared to 28 days) on the urine concentrations of PREG or ALLO in depression. Secondary outcomes were the effect of clinical response and time on the urine concentration of PREG or ALLO, independently of the antidepressant given (mirtazapine or venlafaxine). Linear mixed models were carried out.
Results
Regarding our primary outcome, there was no significant difference in PREG and ALLO concentrations between baseline and 28 days in responders and non-responders when investigating the venlafaxine or the mirtazapine group. However, concerning our secondary outcomes, we found a significant reduction of urine PREG concentration after 28 days of treatment in responders who received either venlafaxine or mirtazapine (estimate = -0.56; p = 0.016; 95CI [-1.003; -0.115]; Cohen’s d = -0.61).
Conclusions
Our main results indicate that responders in depression show reduced urinary PREG concentrations after 4-weeks of therapy, independently of the antidepressant used. More studies are needed to confirm these findings.
POTENTIAL OVERUSE OF CT IMAGING BY VARIOUS CLINICAL DEPARTMENTS OF A TERTIARY CARE TEACHING HOSPITAL
Authors:   Mahavir Institute of Medical Sciences, Vikarabad, Telangana, India, 501101., Shreya Mavoori , Krutika Nayak ,   University of Maryland, Baltimore Country, 1000 Hilltop Cir, Baltimore, MD 21250, United States.
Published: January 2023

Computerized Tomography, commonly called as the CT scan is an ionizingnon-invasive, modality which uses combination of series of X ray images taken from the different angles to create cross-sectional images of the body. Even after the advent of advanced imaging techniques such as MRI, CT is still holds an edge over it because of its cost-effectiveness, availability and faster results. But all these factors are also seen to cause an adverse impact leading to overuse or unethical use of the CT regardless of the radiation exposure.In tertiary care teaching hospital, 200 patients attending out-patients and in-patients from all the clinical departments were taken into the study. They were categorized based on their age and the indication of CT imaging (underlying medical condition).The study showed a gradual rise in the CT investigation with increasing age upto the age of 70 years. It was observed that, highest CT imaging were done for the middle-aged group of 50-70 years and least being extremes of below 18 age group. The leading causes for which CT was most requested, were found to be for pre-surgical screening during COVID19 pandemic, followed by COVID19 infection severity detection, head trauma, suspected cases of stroke, renal stones and rhinosinusitis being the fifth leading causes respectively.The present research concludes that, CT investigation is an important benchmark in the field of diagnostic medicine, but careful scrutiny is required while advising these modalities to avoid the unnecessary radiation exposure. Hospital authorities must be responsible to prepare strict guidelines and frequent workshops should be conducted for health professionals to acquaint them with the updated guidelines, for recommending radiation involved imaging to maintain a cost-benefit balance, where the benefit is the diagnostic advantage and the cost being the radiation exposure.
ELIMINATION OF MTCT OF HIV IN INDIA BY 2030: CURRENT STATUS AND THE WAY AHEAD
Authors: Nithin Deepak S. , Gayatri Jambukumar J.
Published: January 2023

Background:Considering the global public health priority of eliminating Mother-to-child transmission (MTCT) of HIV, World Health Organization (WHO) started the initiative of Global Plan Towards Eliminating New HIV Infections Among Children by 2015 and Keeping Their Mothers Alive. Owing to those efforts, the number of children aged between 0-14 years acquiring HIV has decreased since 2011, but not rapidly enough. India is one among the 23 focus countries and while Cuba, Maldives, Thailand and recently Sri Lanka have successfully eliminated MTCT of HIV, India is lagging behind in this ambitious goal despite sustained efforts. Methods: A systematic review of recent literature on MTCT of HIV, current global and Indian status regarding MTCT and the successful approach and methods of countries which were certified by WHO as to have eliminated MTCT of HIV was performed and analysed. Results: As MTCT of HIV has three distinct points â€“ during pregnancy, during delivery and during breastfeeding, the approaches to prevent MTCT also focus on these points chiefly. However, educating the adolescent girl and women of child bearing age would serve as the primordial prevention which also enormously reduces the burden among the three points mentioned above. Awareness also pave a way for volunteering in testing for HIV before planning for pregnancy and regularly checking if the mother found to be HIV positive, keeping the viral load under the desired level in addition to adherence to ART wherever necessary. Discussion: Focusing in all areas where there is possibility of MTCT, Promoting antiretroviral therapy adherence to mothers and children, Involving community level workers, Improved case detection and Strengthening of health system are the measures to be followed in order to achieve elimination of MTCT of HIV in India Conclusion: In the developing countries like India early diagnosis, awareness and the community participation and in collaboration with NGOs can help to achieve the target of elimination of MTCT of HIV.
STUDY OF LIPID PROFILE OF PATIENT WITH ACUTE MYOCARDIAL INFARCTION
Authors:   Department of General Medicine., Patidar Nihar ,   Sri Aurobindo Medical College & Postgraduate Institute-Indore (M.P.)-India., Kumar Kshitij ,   Department of General Medicine., Gupta B.B. ,   Sri Aurobindo Medical College & Postgraduate Institute-Indore (M.P.)-India., Jha R.K. ,   Sri Aurobindo Medical College & Postgraduate Institute-Indore (M.P.)-India.
Published: January 2023

Background- There is discussion over the biomarker potential of using different lipid fractions to predict the risk of acute myocardial infarction (AMI). In order to compare the lipid profiles of 67 AMI patients, we looked at serum total cholesterol (TC), low-density lipoprotein cholesterol (LDL), high-density lipoprotein cholesterol (HDL), and triglycerides (TG). Material And Method- A prospective, cross-sectional study was conducted in the SAIMS emergency/opd. Within 24hours of onset of chest pain. All patients admitted with AMI were included after providing informed consent. Results- Among 200 AMI Patients included 100 STEMI (ST- elevated myocardial infarction) patients, 100 NSTEMI (non-ST-elevated myocardial infarction) patients. The median age of STEMI patient was 57.7years while that of NSTEMI patients 60.3 years. BMI of STEMI 24.6 kg/m2 and NSTEMI 24.9 kg/m2. History of diabetes was present in 22% STEMI patient while that of NSTEMI patients 39%. History of hypertension is present in 52 % STEMI patient and 68% of NSTEMI patients. 49 % STEMI patients were currently smoking while only 36% among NSTEMI patients. Conclusion- The lipid paradox exists for STEMI patients LDL-C and TC levels and hospitalisation, 30-day, and 1-year mortality. NSTEMI patients have a lipid pseudo-paradox. HDL-C, myocardial infarction type, and hospital death are interrelated. These results need more study.
CONGENITAL SWAN NECK DEFORMITY: A CASE REPORT AND REVIEW OF LITERATURE
Authors: Ali Shash Hani , Abdulaziz Alghamdi Abdulrahman , Fahad Almarzouq Sawsan , Ali Shash Hayam
Published: January 2023

Many theories have been suggested for the etiology of congenital swan neck deformity. The one main theory is that there is a lack of anatomical balance of the extrinsic and intrinsic muscles of the finger that is affected. Also, due to the imbalance between the flexors and extensors, flexion at the proximal interphalangeal joint results. As the patient gets older, there is increased lag in the extensors leading to worse flexion deformity, and this is mainly an aesthetic rather than a purely functional problem.A seven-month-old female infant presented with a hand deformity (congenital swan neck deformity on the fifth finger) that started appearing spontaneously and insidiouslywhen the infant was six months old. Operations for this type of deformity can range from skin plasties, artholysis, tenotomies, tendon transfers, and osteotomies to arthrodesis.Postoperative care consists of a splint, in which the duration in which it is kept is based on the technique used.
Engagement With Gamification Elements in a Smoking Cessation App and Short-term Smoking Abstinence: Quantitative Assessment
Authors: Rajani Nikita B , Bustamante Luz , Weth Dominik , Romo Lucia , Mastellos Nikolaos , Filippidis Filippos T
Published: January 2023

Background

Gamification in smoking cessation apps has been found to improve cognitive outcomes associated with higher odds of quitting. Although some research has shown that gamification can also positively impact behavioral outcomes such as smoking cessation, studies have largely focused on physical activity and mental health. Only a few studies have explored the effects of gamification on smoking cessation outcomes, of which the majority have adopted qualitative methodologies and/or assessed engagement with apps using self-report.

Objective

This study aimed to explore levels of user engagement with gamification features in a smoking cessation app via in-app metrics. Specifically, the objective of this paper was to investigate whether higher engagement with gamification features is associated with the likelihood of quitting in the short term.

Methods

Data from a larger online study that recruited smokers seeking to quit were analyzed to address the objectives presented in this paper. The study took place between June 2019 and July 2020, and participants were primarily recruited via social media posts. Participants who met the eligibility criteria used 1 of 2 mobile apps for smoking cessation. In-app metrics shared by the developer of one of the smoking cessation apps, called Kwit, were used to assess engagement with gamification features. Out of 58 participants who used the Kwit app, 14 were excluded due to missing data or low engagement with the app (ie, not opening the app once a week). For the remaining 44 participants, mean (SD) values were calculated for engagement with the app using in-app metrics. A logistic regression model was used to investigate the association between engagement with gamification and 7-day smoking abstinence.

Results

In total, data from 44 participants who used the Kwit app were analyzed. The majority of participants were male, married, and employed. Almost 30% (n=13) of participants self-reported successful 7-day abstinence at the end of the study. On average, the Kwit app was opened almost 31 (SD 39) times during the 4-week study period, with the diary feature used the most often (mean 22.8, SD 49.3). Moreover, it was found that each additional level unlocked was associated with approximately 22% higher odds of achieving 7-day abstinence after controlling for other factors such as age and gender (odds ratio 1.22, 95% CI 1.01-1.47).

Conclusions

This study highlights the likely positive effects of certain gamification elements such as levels and achievements on short-term smoking abstinence. Although more robust research with a larger sample size is needed, this research highlights the important role that gamification features integrated into mobile apps can play in facilitating and supporting health behavior change.
The Determinant Factors of the Public Open Space Activity in Patukan Rail-Station Area, Sleman, Yogyakarta
Authors: Bekti Bekti Sulistya , Tarcicius Yoyok Wahyu Subroto
Published: January 2023

The phenomenon of public open space activity in Patukan railroad area is a spatial problem related to the behavior of its users. Residents around Patukan railway station use the railroad crossing area as a place to gather, culinary tours and recreation while watching train activities that pass in the afternoon. Activities that occur in the area raise concerns about the security and safety of visitors who are active there considering that the majority of visitors carry out these activities on railroad tracks. PT. Indonesian Railways (KAI) Daop VI Yogyakarta as the manager of Patukan railway station has banned any activity in the area, but the regulation is still not effective enough to prevent people from gathering in that area. This study aims to identify the phenomenon of activity that occurs in the Patukan railway station area and to determine the factors that cause the setting of public open space activities in that area by using a qualitative and quantitative method based on rationalism. Based on the results of the study it is known that there are factors that cause the setting of public open space activities in the area consisting of perception, time, environmental and spatial factors that support activity actors to carry out activities there.
Comparative Study of Prefabricated Temporary Shelters Based on The National Temporary Shelter of Republic Indonesia
Authors: Falza Fariz Muhammad , Hariyadi Agus
Published: January 2023

Penelitian ini merupakan studi perbandingan hunian sementara dengan pendekatan prefabrikasi. Penelitian ini dilakukan berdasarkan kebutuhan akan preseden desain hunian sementara dengan pendekatan prefabrikasi yang dapat tetap mendekati standar hunian sementara pemerintah (setidaknya mendekati spesifikasi dan anggaran). Penelitian ini akan membandingkan spesifikasi dan anggaran dari 9 model hunian sementara prefabrikasi berdasarkan standar hunian sementara Nasional Indonesia. Tujuannya adalah untuk menemukan preseden untuk hunian sementara prefabrikasi yang lebih mendekati standar hunian sementara di Indonesia. Metode dalam penelitian ini menggunakan beberapa metode yaitu kuantitatif dalam deskripsi data awal, kualitatif dalam penilaian akhir, yang dipadukan dengan perbandingan skor yang diberikan pada setiap shelter. Hasil dari penelitian ini adalah ditemukannya dua tipe hunian sementara prefabrikasi yang cukup mendekati standart hunian sementara Nasional Indonesia berupa sampel F 33 titik dan sampel E 30 titik. Hasil ini banyak dipengaruhi oleh dua faktor: pemilihan bahan dan penilaian poin di tempat penampungan.
Formulating Technical Policies Solution to Reduce Urban Heat Island in The City of Yogyakarta
Authors: Puspita Belinda , Wibisono Bambang Hari , Saleh Mohamed
Published: January 2023

UHIs are one of the challenges that has arisen from urbanization in Yogyakarta. These phenomena require the development of guidelines and planning policies which can manage the local climate. This research aims to formulate the spatial planning policies solution which use the concepts of urban sustainability and sustainable cooling to reduce UHI. Qualitative analysis was conducted through the analysis of the data from interviews on the multilevel governments based on spatial planning policies and the implementation. This spatial planning solution is divided in three solutions: technical policies, strategic policies, and partnership. The technical policies offer expanded vegetation area and living lab projects. Then the strategic policies consist of the cooling action plan and the incentive-disincentive mechanism. The last solution, partnership, is offered engagement with the public and collaboration with other cities or private parties. The spatial planning policies solutions which have high chance to reduce UHI, as determined from the interviews, is from technical policies and should be implemented by expanding green areas and forming urban living labs. The governments also offer three alternative solutions i.e. expanding green area combine with smart surface strategy, establishing cooling strategic plan, and penta-helix collaboration.
The Future of Design? Review of EveryRealm’s The Row, Impossible Architecture in the Metaverse
Authors: Barry Kristin M.
Published: January 2023

None
An Approach on the Development of a Smart Monitoring System of a Baby Cradle
Authors: Teotia Monu , Sharma Manu , Dubey Kuldeep , Shukla Amrendra Mohan , Vats Mayank , Saini Garima
Published: January 2023

Abstract: Baby care has grown increasingly vital and difficult for working women in recent years. Working mothers will not have enough time at home to regularly check their babies. They delegate responsibility for their baby to a baby sitter or send the baby to their grandparents' home. A smart cradle with an automatic baby monitoring system was designed in the proposed work. The necessary parameters of the infant, such as temperature, heartbeat rate, gas molecules, capture the movements, and position of the baby, were measured and monitored in the baby monitoring system. The infant monitoring system is connected to the cradle, creating an incubator-like environment for the baby. The infant monitoring device keeps an eye on the baby 24 hours a day, seven days a week. The mobile application will display the measured parameters concerning the baby's health, such as temperature, heartbeat rate, and wetness on the baby bed. The baby monitoring system prototype aids parents in time management while also making life easier for caregivers. This infant monitoring device has been shown to do the least amount of harm to the baby while providing the highest level of accuracy. Though several models are already available on the market, the primary goal of this research paper would be to propose an approach for recognizing a particular accent of an individual infant among a group of infants using advanced technologies like as Ai, NLP, or speech recognition.
Study on Population Variation and Phylogeography of Cherry in China（Cerasus conradinae）
Authors: Dong Jing-Jing , Yi Xian-Gui , Wang Xian-Rong , tong wu , Chen Jie , hong Yang , huajing zhou , shucheng Gao , xiangzhen chen , meng LI
Published: January 2023

Cerasus conradinae is an important germplasm resource of wild cherry in
China. In this work, sampling was expanded and genetic evidence was
added for further study. The current and future potential populations
were predicted by niche model. Based on three cpDNA sequences and one
nrDNA sequence, and combined with the phylogeographic evolution of 12
populations of 244 individuals in C.conradinae, the temporal and spatial
patterns of genetic variation in C.conradinae were investigated, and the
effects of genetic drift and differentiation as well as natural
environmental factors on the genetic variation and evolutionary
distribution of C.conradinae were elucidated. Finally, morphological
evidence combined with molecular evidence was used to discuss the
species definition of population variation and differentiation. The
results showed that Central China, East China and Southwest China were
the core regions for the conservation and utilization of germplasm
resources of C.conradinae. Support for variant Cerasus conradinae var.
ruburm is established. The genetic diversity of C.conradinae was high
(Hd = 0.830; Rd = 0.798). There was genetic variation among populations
of C.conradinae, and genealogical geographic structure existed among the
populations and three geographical groups, but the genetic
differentiation coefficient at each level was low. The gene exchange was
obvious in Southwest China, and the differentiation was obvious in
Central China. The population and three geographic groups do not reject
the expectation of expansion model. Two distinct lineages (three
geographic groups) were identified from the population of C.conradinae:
Central China+ East China lineage and East China+ (Central
China+Southwest China) lineage, two lineages of 4.38Mya occurred in the
early Pliocene based on geographical isolation. The southeastern part of
Eastern China near Mount Wuyi was the most likely refuge for
C.conradinae. The results provided a theoretical basis for the
classification and identification of C.conradinae and the protection and
utilization of germplasm resources.
Changes in health literacy assessment of Vidzeme statistical region in Latvia
Authors:   Latvia University, Kodrica Baiba , Grizane Tamara
Published: January 2023

The ability to find, understand, evaluate and use information about an individual’s health during the Covid-19 pandemic has become crucial. Therefore, health literacy (HL) skills development in Latvia, also in other OECD countries, is a priority area. Insufficient HL information base in Latvia is a fundamental basis for the research goal: to determine factors influencing HL and their changes among the population of Vidzeme statistical region (LV008) in Latvia. The study compares the authors’ 2020 study based on the European Health Literacy Questionnaire (HLS-EU-Q47). The study includes survey of respondents (n = 383) using pen-and-paper interviewing (PAPI) and telephone interview approach. Various methods and tests were used: Principal axis factor analysis (PFA) with varimax rotation, Confirmatory factor analysis (CFA), Compare means Independent-sample T-test, Anova, Kaiser-Mayer-Olkin (KMO), Bartlett’s test and Chi-squared test, Cronbach’s and Spearman-Brown methods, correlations (Pearson and Spearman’s) and Multiple linear regression (MLR) with Assumption Testing analysis, and Cronbach’s test. The study identified four factors influencing health literacy: access, understanding, evaluation, and use. Compared to the study conducted by the authors in 2020, which determined that education has a positive impact on factor – access, the HL has increased more strongly in the age groups 18-19, 20-29 and 30-39. However, among women the HL level has decreased compared to the previous study by authors and HLS-EU, the proportion of people with sufficient and excellent HL in the European Union has increased overall by 13.5%, while the proportion of people with limited HL decreased by 24.4%.
Importance of innovations for entrepreneurship development – views of entrepreneurs in Kurzeme region
Authors:   Ventspils University of Applied Sciences, Stefenberga Dace , Sloka Biruta ,   University of Latvia, Rivza Baiba ,   Latvia University of Life Sciences and Technology
Published: January 2023

Innovation is one of the most influential aspects for entrepreneurship development. Therefore, also academic researchers pay a lot of attention on different aspects related to innovations. Current research paper is devoted to evaluation of the views of entrepreneurs related to innovation practical applications and problems of introduction of innovations. Aim: evaluate the views of entrepreneurs related to innovation practical applications and problems of introduction of innovations. Research methods applied: previous conducted scientific research results analysis, analysis of statistical data, survey of entrepreneurs. Survey data are analysed by most used characteristics of descriptive statistics: indicators of central tendency or location (arithmetic mean, mode, median) and by indicators of variability or dispersion using standard deviation, standard error of mean and range. Most important results by views of entrepreneurs are: innovations support increase of expert and increase of share in realization of products or services.
European Union funding support to Latvian municipalities for degraded areas revitalization
Authors:   Latvia University of Life Sciences and Technologies, Stepina Mairita , Pelse Modrite ,   Latvia University of Life Sciences and Technologies
Published: January 2023

The formation and existence of degraded areas is one of the consequences of civilization, which has a negative impact on both the environment and economic development in the municipality. The problem of degraded areas has been faced by all countries worldwide, including Latvia, when as a result of the change of the state political system in the 1990s after the collapse of the Soviet system, a large number of inactive production companies appeared, resulting in a significant number of polluted / degraded areas. To solve the existing problem, local governments in Latvia use European Regional Development Fund (ERDF) funding under the Operational Program ‘Growth and Employment’ 5.6.2, specific support objective ‘Revitalization of territories by regenerating degraded areas in accordance with local government integrated development programs’ (SSO 5.6.2) to ensure the sustainable development of the territory by revitalizing degraded areas. In the implementation of projects, local governments must ensure the fulfilment of the indicators planned in the projects in the following groups of indicators: the area of degraded areas has been renewed, adapted for the location of new businesses or expansion of existing businesses in order to promote employment and economic activity in local governments; new jobs created in supported areas; non-financial investments made by businesses located in the supported territory in their own intangible investments and fixed assets. Therefore, it is necessary to evaluate the indicators of the implemented projects in order to be able to draw conclusions about the financial aspects of the project implementation and the progress of the project implementation.
Dual responsive hybrid hydrogels for controlled release of local anesthetic
Authors: Marković Maja D. , Šešlija Sanja I. , Panić Vesna V. , Spasojević Pavle M.
Published: January 2023

Inteligent hydrogels, such as pH sensitive hydrogels based on poly(methacrylic acid) (PMAA) are widely used for targeted drug delivery. Still, PMAA lack of good mechanical properties often limits its application. In order to overcome this limitation nanocellulose (NC) was extracted from wood waste material and then added to PMAA because NC is biocompatible, non-toxic and has excellent mechanical properties. Further, carboxymethyl cellulose (CMC) (cellulose derivate widely used for controlled release of drugs) was added. CMC can stabilize magnetite nanoparticles (MN) which is then also added. MN can significantly improve mechanical properties of hydrogels and also possess magnetic properties due to which MN can be used for targeted drug delivery. The as-prepared material can protect drug, deliver it to the site of action, control its release rate and enable in that way its efficient application with reduced side effects. Local anesthetic - lidocaine hydrochloride (LH) is often administrated by injection which can induce severe side effects. This problem is solved in present study by encapsulating LH into hydrogels based on PMAA, NC, CMC and MN (PMNC/MN-L). PMNC/MN-L hydrogels were characterized by FTIR and SEM spectroscopies and single compressive tests and then their swelling behavior and LH release were analyzed. Present study offers unique approach for green synthesis of dual responsive hydrogels with improves properties and their application for controlled release of local anesthetic with reduced side effects.
Rast indeksa troškova procesnih, energetskih i termotehničkih postrojenјa i opreme tokom 2021. i 2022.
Authors: Genić Srbislav , Stanković Vladislav , Gajić Branislav
Published: January 2023

Svetska ekonomska kriza iz 2008. godine, izazvana specifičnim poslovanjem banaka po pitanju kreditiranja i transakcija sa kreditima, je delimično suprimirana preko pomoći koju su obezbedile, pre svega, najmoćnije države sveta kroz svoje nacionalne banke. Pomoć se sastojala u emisiji novca uz minimiziranje uslova otplate kredita kroz niske kamate.  Nakon 2020. godine, koju je u svetu obeležila pandemija COVID19 virusa, vlade ekonomski najmoćnijih država sveta su pristupile sprovođenju različitih ekonomskih mera radi prevazilaženja ekonomske krize u kojoj se našla praktično čitava planeta. U oba krizna slučaja, skoro istovremeno ili sa manjim vremenskim pomakom, i vlade mnogih drugih zemalјa su donosile sopstvene ekonomske mere.
Ispitivanje otpornosti prema požaru požarno otpornih klapni
Authors: Kijanović Aleksandar , Mirković Marjanović Milica , Ilić Snežana
Published: January 2023

Passive fire protection is civil engineering discipline which is very popular for research and development of new construction products and test standards. The primary function of passive fire protection product is to achieve the declared fire resistance. Fire resistance of a construction product is expressed as a time interval (30 min, 60 min, 90 min, 120 min ...) in which certain properties of the tested product are preserved. In the given time intervals, it is necessary for the tested product to maintain the thermal insulation properties (I), integrity (E) and additional properties prescribed by the test standard related to the tested product.  The fire damper represents part of HVAC system installed on walls which are fire resistance barriers [2]. Additional properties related to fire-resistant service installations- fire dampers (hereinafter only fire dampers) are the leakage on the fire damper in the cold state and the leakage of fire damper (S) during the fire test. In order to determine the previous properties, a test installation for fire dampers was formed, which consists of: installed damper in the test wall, duct and pipeline system, system for measuring the volume flow, cooler and a fan. All the obtained results are graphically presented in the paper and serve for the purpose of determining the mentioned fire properties of dampers and for the purpose of fire resistance classification of construction products.
Magnesium and hypertension in the process industry
Authors:   University of Belgrade, Faculty of Medicine, Institute of Hygiene and Medical Ecology, Belgrade, Banjanin Nikolina
Published: January 2023

In the process industry there are many sources of noise. A systematic review and meta-analysis found that occupational noise exposure increases the risk of hypertension. Noise exposure is strongly associated with the prevalence of hypertension in steelworkers. It is shown that in workers in an automobile manufacturing company noise exposure may increase blood pressure. In workplaces where work is performed in which daily noise exposure varies considerably from one to another day the weekly noise exposure must not exceed 85 dB (A). Magnesium has significant role in blood pressure regulation. Magnesium can improve vasodilatation via the release of nitric oxide from the endothelium and has an impact on the inhibition of several vasoconstrictors, stimulation of vasodilatators in the endothelium, and directly or indirectly inhibition of aldosterone production causing decreased kidney reabsorption of sodium and fluid. In western diet the recommended magnesium intake may be hardly reached due to food processing and food refining. In Serbia, nutritive magnesium intake in patients with essential hypertension is significantly below the recommended values. In men aged ≤ 30 years magnesium intake is 2.4 times less than recommended, and in women of the same age it is 55.2 % compared to recommended. In men aged ≥ 31 years magnesium intake is 47,1 % compared to recommended, and in women of the same age it is 56,2% compared to recommended. A systematic-review and meta-analysis of prospective cohort studies found an inverse relationship between dietary magnesium intake and the hypertension risk.
Characterization and utilization of novel exopolysaccharide isolated from klebsiella oxytoca j7, in the biosorption studies of removal of Pb2+ and Ni2+ ions from wastewater
Authors:   University of Belgrade, Institute of Chemistry, Technology and Metallurgy, National Institute of Republic of Serbia, Belgrade, Ljubić Verica
Published: January 2023

Exopolysaccharides (EPS), as biopolymers, are very common in nature. These are high molecular weight biopolymers, which have applications in various industries, and as such have attracted the attention of researchers around the world in recent years. Considering this, the main advantages of biosorption are low cost, high efficiency of metal removal from dilute solution, minimization of chemical and / or biological sludge, no additional nutrients and regeneration of biosorbent, exopolysaccharides have found application in these processes. Therefore, in this study, a new biopolymer, exopolysaccharide was isolated from Klebsiella oxytoca J7 strain, and, was studied to remove nickel and lead from wastewater. After characterization by SEM, FTIR, TGA analysis, the obtained results showed that EPS was isolated from strain K. oxytoca J7, is stable, and obtain a good nickel removal efficiency, 98.9%, while the removal efficiency for lead was 89.2%. Therefore, this exopolysaccharide can find its application in the treatment of contaminated water with heavy metals.
Influence of ORC working fluids on the efficiency of a combined system integrated with fuel cell, gas turbine, organic Rankine cycle and steam turbine
Authors:   JP Elektroprivreda BiH, Termoelektrana Tuzla, Ćehajić Nurdin
Published: January 2023

The paper analyzes the influence of working fluids on the efficiency of the combined system integrated with solid oxide fuel cell (SOFC), gas turbine (GT), organic Rankine cycle (ORC) and steam turbine. Based on the mathematical model under the same heat source conditions and defined limit conditions, the analysis and comparison of the obtained values of efficiency and losses of individual cycles and the complete combined system for ORC working fluids m-xylene, toluene and MDM (OMTS) was performed. Pre-selected working fluids for the use of heat generated in SOFC and GT after the work is performed must meet environmental, safety and thermodynamic criteria. A comparative analysis of the obtained results of losses and efficiency will show which of the pre - selected working fluids under the same operating conditions has the greatest impact on the efficiency of the ORC and the combined system SOFC - GT - ORC - PT. The obtained results of individual efficiencies of SOFC, GT, ORC and PT will be the basis for determining the percentage increase in efficiency of quadruple combined system compared to stand-alone SOFC, hybrid SOFC-GT and triple combined system SOFC-GT-PT, for ORC with all three working fluid.
Analysis of the ISO 30405 standard for personnel recruitment and its importance in the business of organizations
Authors:   University of Belgrade, Faculty of organizational sciences, Belgrade, Đurić Mladen
Published: January 2023

This paper provides a detailed analysis of one of the standards in human resource management, ISO 30405. This standard provides specific guidelines for the recruitment process and, within this paper, highlights the importance of ISO 30405 for the recruitment process and the overall business. The successful business of any organization is based on quality and motivated staff, which is achieved through the recruitment process. From this, it is concluded that successful recruitment is one of the main prerequisites for the success of organizations in business, and when we take into account the fact that the ISO 30405 standard ensures the quality of the recruitment process, we come to a key dependence. importance for the business organization itself.All five points of the ISO 30405 standard are analyzed in this paper, including their sub-points. The first three points of this standard provide a detailed, informative introduction to the standard and its application. They highlight the subject, scope, and normative references related to the standard and basic terms and their definitions that are crucial for understanding the recruitment process itself, as well as the ISO 30405 standard itself. The fourth point is the core of this standard because Specific guidelines for the recruitment process are highlighted. The fifth point of this standard refers to the measurement, analysis, and improvement within the recruitment process, more precisely describing the measurement process and guidelines regarding the necessary measures and methods of analyzing the results of these measurements to improve it. The concluding part of the paper presents the sublimation of all guidelines of the ISO 30405 standard and emphasizes its importance, primarily in the recruitment process, and then with the help of a cause-and-effect relationship, its importance in the business of organizations.
Overview of standards for the food industry and related supply chains
Authors:   University of Belgrade, Faculty of organizational sciences, Belgrade, Đurić Mladen
Published: January 2023

In the business world, as well as in everyday life, there is an increasing number of needs, requirements, and expectations that need to be met to ensure mutual satisfaction. To achieve this, standards are increasingly taking place within the business of organizations, to make business simpler, safer, and more secure. By applying and introducing standards, companies achieve continuous improvement of their performance as well as a competitive advantage.The aim of this paper is to present the standards for companies from the food industry and their supply chain. Knowing that the food industry is very specific in terms of safety and quality, a number of standards have been developed to prevent possible inconsistencies on this issue, which may affect human and animal health. All actors in the supply chain, and especially end users, demand that the products that reach them be safe, which gains trust in the organization. Organizations are increasingly introducing standards and systems that will enable the safety and quality of their products, after which improvements in the performance of the organization are realized.
El ordenamiento jurídico como garantía de seguridad y confianza en el sistema tributario Colombiano
Authors: Cabrera Jaramillo Ruby Stella , Ortiz Sánchez Luz Mery , Pérez Arias Eliana Andrea , Orozco Cataño Yuranny Paola
Published: January 2023

El ordenamiento jurídico en un Estado social de derecho, como Colombia, proporciona seguridad, certeza y confianza en el sistema tributario, fuente principal de ingresos para financiar los fines esenciales del mismo.  Siendo así, la relación jurídica que se desprende de la obligación tributaria, más que una relación de poder entre las partes, las subordina a en igualdad de condiciones a la potestad e imperio de la Constitución y la ley, lo cual implica que, previamente los contribuyentes deben conocer la forma en que actuará la administración tributaria y las consecuencias presentes y futuras de su conducta. De esta forma, el sujeto pasivo podrá darle un manejo oportuno al riesgo fiscal sin comprometer la sostenibilidad financiera empresarial o personal. Se utiliza el método hermenéutico, a partir de la comprensión de supuestos teóricos, el análisis de categorías y conceptos a través de los cuales se concluye que, el orden jurídico tributario, no siempre garantiza seguridad, certeza y confianza jurídica, situación que subyace de la coyuntura política, económica y social en el contexto interno y externo.
Metodologías activas para la enseñanza del presupuesto público en los programas de Contaduría Pública en Colombia
Authors: Pinilla Sánchez Martha Patricia , Oviedo Elizabeth
Published: January 2023

El propósito de este trabajo es presentar los aspectos relevantes de las metodologías activas en la enseñanza del Presupuesto Público dirigido a la formación de contadores Públicos en Colombia. A partir de la revisión de la literatura se muestra como las metodologías activas permiten generar un aprendizaje significativo para la enseñanza del presupuesto público en estudiantes de Contaduría Pública. Se advierte la necesidad de los docentes de incluir dentro de su labor, las metodologías activas para formar profesionales con autonomía, pensamiento crítico, trabajo cooperativo, habilidades comunicativas y creatividad.
Auditorías fiscales a operaciones de arrendamiento de inmuebles entre partes relacionadas en México
Authors: Landa Fournais Luis Enrique
Published: January 2023

Este estudio se plantea con la finalidad de investigar los avances conceptuales, metodológicos y empíricos de la auditoría forense (AF) para prevenir el fraude contable. Para lograr la pretensión de este estudio se utilizará una metodología cualitativo documental, la cual se centrará en la identificación, análisis en interpretación de la información, entre las cuales se incluyen artículos científicos, tesis de grado, libros, entre otros. Los resultados indicaron que el concepto de auditoría forense es diverso a través de los años; así mismo, o existe una metodología concreta en lo que respecta la aplicación y desarrollo de la AF y las empresas no tienen un modelo establecido de auditoría forense. Finalmente se identificó que la responsabilidad del auditor está directamente vinculada a la prioridad que las empresas otorguen al proceso. En conclusión, debe seguirse desarrollando estudios que permitan generar una conceptualización integral frente a la AF, además, desarrollar una metodología que pueda ser aplicada por las empresas desde lo empírico y bajo el asesoramiento y responsabilidad del auditor forense.
The Interactions between Universes and its Effect on the Cosmological Constant in a Multiverse with Regularized Big Bangs
Authors: McGraw Jr. David
Published: January 2023

The total universe is made up of many universes like our own. These different universes can interact in many different ways. These collisions are essential for the development of each of the many universes. Because of this interaction, a process is started so that the landscape structure where the universes develop leads us to different practical values of the cosmological constant. So then, quantum tunneling plays a vital role in the rise of the new areas created by the Universal interacts. This leads to the values of their vacuum state. The interacting universes and the new areas that they create depend on just small regions of Spacetime. The quantum effects are significant only in this Spacetime. These new areas that develop help to develop different areas of a continuous process.