bluuebunny/crossref_metadata_2025 huggingface dataset:
Nationwide analysis of hospital-to-hospital transfer in patients with aneurysmal subarachnoid hemorrhage requiring aneurysm repair
Authors: Roark Christopher , Case David , Gritz Mark , Hosokawa Patrick , Kumpe David , Seinfeld Joshua , Williamson Craig A. , Libby Anne M.
Published: November 2018

OBJECTIVE

Aneurysmal subarachnoid hemorrhage (aSAH) has devastating consequences. The association between higher institutional volumes and improved outcomes for aSAH patients has been studied extensively. However, the literature exploring patterns of transfer in this context is sparse. Expansion of the endovascular workforce has raised concerns about the decentralization of care, reduced institutional volumes, and worsened patient outcomes. In this paper, the authors explored various patient and hospital factors associated with the transfer of aSAH patients by using a nationally representative database.

METHODS

The 2013 and 2014 years of the National Inpatient Sample (NIS) were used to define an observational cohort of patients with ruptured brain aneurysms. The initial search identified patients with SAH (ICD-9-CM 430). Those with concomitant codes suggesting trauma or other intracranial vascular abnormalities were excluded. Finally, the patients who had not undergone a subsequent procedure to repair an intracranial aneurysm were excluded. These criteria yielded a cohort of 4373 patients, 1379 of whom had undergone microsurgical clip ligation and 2994 of whom had undergone endovascular repair. The outcome of interest was transfer status, and the NIS data element TRAN_IN was used to define this state. Multiple explanatory variables were identified, including age, sex, primary payer, median household income by zip code, race, hospital size, hospital control, hospital teaching status, and hospital location. These variables were evaluated using descriptive statistics, bivariate correlation analysis, and multivariable logistic regression modeling to determine their relationship with transfer status.

RESULTS

Patients with aSAH who were treated in an urban teaching hospital had higher odds of being a transfer (OR 2.15, 95% CI 1.71–2.72) than the patients in urban nonteaching hospitals. White patients were more likely to be transfer patients than were any of the other racial groups (p < 0.0001). Moreover, patients who lived in the highest-income zip codes were less likely to be transferred than the patients in the lowest income quartile (OR 0.78, 95% CI 0.64–0.95). Repair type (clip vs coil) and primary payer were not associated with transfer status.

CONCLUSIONS

A relatively high percentage of patients with aSAH are transferred between acute care hospitals. Race and income were associated with transfer status. White patients are more likely to be transferred than other races. Patients from zip codes with the highest income transferred at lower rates than those from the lowest income quartile. Transfer patients were preferentially sent to urban teaching hospitals. The modality of aneurysm treatment was not associated with transfer status.
Transcortical insular glioma resection: clinical outcome and predictors
Authors: Hameed N. U. Farrukh , Qiu Tianming , Zhuang Dongxiao , Lu Junfeng , Yu Zhengda , Wu Shuai , Wu Bin , Zhu Fengping , Song Yanyan , Chen Hong , Wu Jinsong
Published: November 2018

OBJECTIVE

Insular lobe gliomas continue to challenge neurosurgeons due to their complex anatomical position. Transcortical and transsylvian corridors remain the primary approaches for reaching the insula, but the adoption of one technique over the other remains controversial. The authors analyzed the transcortical approach of resecting insular gliomas in the context of patient tumor location based on the Berger-Sinai classification, achievable extents of resection (EORs), overall survival (OS), and postsurgical neurological outcome.

METHODS

The authors studied 255 consecutive cases of insular gliomas that underwent transcortical tumor resection in their division. Tumor molecular pathology, location, EOR, postoperative neurological outcome for each insular zone, and the accompanying OS were incorporated into the analysis to determine the value of this surgical approach.

RESULTS

Lower-grade insular gliomas (LGGs) were more prevalent (63.14%). Regarding location, giant tumors (involving all insular zones) were most prevalent (58.82%) followed by zone I+IV (anterior) tumors (20.39%). In LGGs, tumor location was an independent predictor of survival (p = 0.003), with giant tumors demonstrating shortest patient survival (p = 0.003). Isocitrate dehydrogenase 1 (IDH1) mutation was more likely to be associated with giant tumors (p < 0.001) than focal tumors located in a regional zone. EOR correlated with survival in both LGG (p = 0.001) and higher-grade glioma (HGG) patients (p = 0.008). The highest EORs were achieved in anterior-zone LGGs (p = 0.024). In terms of developing postoperative neurological deficits, patients with giant tumors were more susceptible (p = 0.038). Postoperative transient neurological deficit was recorded in 12.79%, and permanent deficit in 15.70% of patients. Patients who developed either transient or permanent postsurgical neurological deficits exhibited poorer survival (p < 0.001).

CONCLUSIONS

The transcortical surgical approach can achieve maximal tumor resection in all insular zones. In addition, the incorporation of adjunct technologies such as multimodal brain imaging and mapping of cortical and subcortical eloquent brain regions into the transcortical approach favors postoperative neurological outcomes, and prolongs patient survival.
Changes in the gray and white matter of patients with ischemic-edematous insults after traumatic brain injury
Authors: Kim Hakseung , Kim Young-Tak , Song Eun-Suk , Yoon Byung C. , Choi Young Hun , Kim Keewon , Kim Dong-Joo
Published: November 2018

OBJECTIVE

Gray matter (GM) and white matter (WM) are vulnerable to ischemic-edematous insults after traumatic brain injury (TBI). The extent of secondary insult after brain injury is quantifiable using quantitative CT analysis. One conventional quantitative CT measure, the gray-white matter ratio (GWR), and a more recently proposed densitometric analysis are used to assess the extent of these insults. However, the prognostic capacity of the GWR in patients with TBI has not yet been validated. This study aims to test the prognostic value of the GWR and evaluate the alternative parameters derived from the densitometric analysis acquired during the acute phase of TBI. In addition, the prognostic ability of the conventional TBI prognostic models (i.e., IMPACT [International Mission for Prognosis and Analysis of Clinical Trials in TBI] and CRASH [Corticosteroid Randomisation After Significant Head Injury] models) were compared to that of the quantitative CT measures.

METHODS

Three hundred patients with TBI of varying ages (92 pediatric, 94 adult, and 114 geriatric patients) and admitted between 2008 and 2013 were included in this retrospective cohort study. The normality of the density of the deep GM and whole WM was evaluated as the proportion of CT pixels with Hounsfield unit values of 31–35 for GM and 26–30 for WM on CT images of the entire supratentorial brain. The outcome was evaluated using the Glasgow Outcome Scale (GOS) at discharge (GOS score ≤ 3, n = 100).

RESULTS

Lower proportions of normal densities in the deep GM and whole WM indicated worse outcomes. The proportion of normal WM exhibited a significant prognostic capacity (area under the curve [AUC] = 0.844). The association between the outcome and the normality of the WM density was significant in adult (AUC = 0.792), pediatric (AUC = 0.814), and geriatric (AUC = 0.885) patients. In pediatric patients, the normality of the overall density and the density of the GM were indicative of the outcome (AUC = 0.751). The average GWR was not associated with the outcome (AUC = 0.511). IMPACT and CRASH models showed adequate and reliable performance in the pediatric and geriatric groups but not in the adult group. The highest overall predictive performance was achieved by the densitometry-augmented IMPACT model (AUC = 0.881).

CONCLUSIONS

Both deep GM and WM are susceptible to ischemic-edematous insults during the early phase of TBI. The extent of the secondary injury was better evaluated by analyzing the normality of the deep GM and WM rather than by calculating the GWR.
Harvey Cushing’s craniopharyngioma treatment: Part 2. Surgical strategies and results of his pioneering series
Authors: Prieto Ruth , Pascual José María , Barrios Laura
Published: November 2018

OBJECTIVE

Harvey Cushing (1869–1939) developed pioneering surgical techniques for craniopharyngioma (CP) removal. This study exhaustively analyzes the pathological variables and surgical strategies that influenced Cushing’s results in his entire series of CP patients.

METHODS

The CP records from Cushing’s Brain Tumor Registry were carefully reviewed, as were his CP cases published in medical monographs and scientific reports.

RESULTS

One hundred twenty-four tumors with characteristics typical of CP comprise Cushing’s entire series (CP124). Cushing performed 198 surgical procedures in the patients in whom these tumors were treated, with a 23% mortality rate within the first 2 months after surgery. Three periods in Cushing’s CP surgical career can be differentiated: an early period (1901–1917, 39 patients) characterized by his use of the transsphenoidal approach and limited cyst drainage procedures, an intermediate period (1919–1925, 42 patients) in which the subfrontal approach was the standard procedure and maximal removal was attempted, and a late period (1926–1932, 43 patients) characterized by the use of air ventriculography for topographical diagnosis and limited resections via a transventricular approach. Among Cushing’s CP series were 92 cases that were pathologically verified (CP92). In this subcohort, the unilateral subfrontal approach was predominantly used (72% of cases), followed by the transsphenoidal (15%) and frontal transcortical-transventricular (8%) approaches. Drainage of the CP cystic component or partial excision of the solid component was achieved in 61% of the cases, subtotal removal in 23%, and macroscopic total removal in 10%. Satisfactory outcomes were obtained in 55% of the patients in CP92, whereas poor outcomes and/or death related to hypothalamic injury was observed in 28%. Postoperative symptoms related to hypothalamic dysfunction occurred 53% of the time. The subfrontal approach yielded the highest rates of radical removal (p < 0.001) and good outcomes (p = 0.01). Partial removals were associated with the highest rates of poor outcomes, including death (p = 0.009). Cushing’s removal of CPs with a primary infundibulo-tuberal topography or showing third ventricle invasion was associated with the highest rates of hypothalamic injury (p < 0.001) and the worst outcomes (p = 0.009).

CONCLUSIONS

Harvey Cushing’s techniques and surgical philosophy varied substantially throughout his career. The experience he gained with this large CP series made him aware of the importance of limiting the extent of tumor removal and leaving untouched the tumor portion strongly adhered to the hypothalamus.
Key anatomical landmarks for middle fossa surgery: a surgical anatomy study
Authors: Peris-Celda Maria , Perry Avital , Carlstrom Lucas P. , Graffeo Christopher S. , Driscoll Colin L. W. , Link Michael J.
Published: November 2018

OBJECTIVE

Middle fossa surgery is challenging, and reliable surgical landmarks are essential to perform accurate and safe surgery. Although many descriptions of the middle fossa components have been published, a clinically practical description of this very complex anatomical region is lacking. Small structure arrangements in this area are often not well visualized or accurately demarcated with neuronavigation systems. The objective is to describe a “roadmap” of key surgical reference points and landmarks during middle fossa surgery to help the surgeon predict where critical structures will be located.

METHODS

The authors studied 40 dry skulls (80 sides) obtained from the anatomical board at their institution. Measurements of anatomical structures in the middle fossa were made with a digital caliper and a protractor, taking as reference the middle point of the external auditory canal (MEAC). The results were statistically analyzed.

RESULTS

The petrous part of the temporal bone was found at a mean of 16 mm anterior and 24 mm posterior to the MEAC. In 87% and 99% of the sides, the foramen ovale and foramen spinosum, respectively, were encountered deep to the zygomatic root. The posterior aspect of the greater superficial petrosal nerve (GSPN) groove was a mean of 6 mm anterior and 25 mm medial to the MEAC, nearly parallel to the petrous ridge. The main axis of the IAC projected to the root of the zygoma in all cases. The internal auditory canal (IAC) porus was found 5.5 mm lateral and 4.5 mm deep to the lateral aspect of the trigeminal impression along the petrous ridge (mean measurement values). A projection from this point to the middle aspect of the root of the zygoma, being posterior to the GSPN groove, could estimate the orientation of the IAC.

CONCLUSIONS

In middle fossa approaches, the external acoustic canal is a reliable reference before skin incision, whereas the zygomatic root becomes important after the skin incision. Deep structures can be related to these 2 anatomical structures. An easy method to predict the location of the IAC in surgery is described. Careful study of the preoperative imaging is essential to adapt this knowledge to the individual anatomy of the patient.
Motor cortex neurovascular coupling: inputs from ultra–high-frequency ultrasound imaging in humans
Authors: Almairac Fabien , Fontaine Denys , Demarcy Thomas , Delingette Hervé , Beuil Stéphanie , Raffaelli Charles
Published: November 2018

OBJECTIVE

Neurovascular coupling reflects the link between neural activity and changes in cerebral blood flow. Despite many technical advances in functional exploration of the brain, including functional MRI, there are only a few reports of direct evidence of neurovascular coupling in humans. The authors aimed to explore, for the first time in humans, the local cerebral blood flow of the primary motor cortex using ultra–high-frequency ultrasound (UHF-US) Doppler imaging to detect low blood flow velocity (1 mm/sec).

METHODS

Four consecutive patients underwent awake craniotomy for glioma resection using cortical direct electrostimulation for brain mapping. The primary motor cortical area eliciting flexion of the contralateral forearm was identified. UHF-US color Doppler imaging of this cortical area was acquired at rest, during repeated spontaneous forearm flexion, and immediately after the movement’s termination. In each condition, the surface areas of the detectable vessels were measured after extraction of non–zero-velocity colored pixels and summed.

RESULTS

During movement, local cerebral blood flow increased significantly by 14.4% (range 5%–30%) compared with baseline. Immediately after the termination of movements, the local hyperemia decreased significantly by 8.6% (range 1.9%–15.7%).

CONCLUSIONS

To the authors’ knowledge, this study is the first to provide a real-time demonstration of the neurovascular coupling in the human cortex by ultrasound imaging. They assume that UHF-US may be used to gather original and advanced data on brain functioning, which could be used to help in the identification of functional cortical areas during brain surgery.

Clinical trial registration no.: NCT03179176 (clinicaltrials.gov)
The cost of hydrocephalus: a cost-effectiveness model for evaluating surgical techniques
Authors: Lim Jaims , Tang Alan R. , Liles Campbell , Hysong Alexander A. , Hale Andrew T. , Bonfield Christopher M. , Naftel Robert P. , Wellons John C. , Shannon Chevis N.
Published: November 2018

OBJECTIVE

Many studies have aimed to determine the most clinically effective surgical intervention for hydrocephalus. However, the costs associated with each treatment option are poorly understood. In this study, the authors conducted a cost-effectiveness analysis, calculating the incremental cost-effectiveness ratio (ICER) of ventriculoperitoneal shunting (VPS), endoscopic third ventriculostomy (ETV), and ETV with choroid plexus cauterization (ETV/CPC) in an effort to better understand the clinical effectiveness and costs associated with treating hydrocephalus.

METHODS

The study cohort includes patients under the age of 18 who were initially treated for hydrocephalus between January 2012 and January 2015 at the authors’ institution. Overall treatment costs were calculated using patient-level hospitalization costs and professional fees reimbursable to the hospital and directly related to the initial and follow-up (postoperative day 1 to 12 months) treatment of hydrocephalus. TreeAge Pro was used to conduct the cost-effectiveness analyses.

RESULTS

A total of 147 patients were identified. Based on the initial intervention for hydrocephalus, their cases were classified as follows: 113 VPS, 14 ETV, and 20 ETV/CPC. During the initial intervention, VPS patients required a longer length of stay at 5.6 days, compared to ETV/CPC (3.35 days) and ETV (2.36 days) patients. Failure rates for all treatment options ranged from 29% to 45%, leading to recurrent hydrocephalus and additional surgical intervention between postoperative day 1 and 12 months. Cost-effectiveness analyses found ETV to be less costly and more clinically effective, with an ICER of $94,797 compared to VPS ($130,839) and ETV/CPC ($126,394). However, when stratified by etiology, VPS was found to be more clinically effective and cost-effective in both the myelomeningocele and posthemorrhagic hydrocephalus patient groups with an incremental cost per clinical unit of effectiveness (success or failure of intervention) of $76,620 compared to ETV and ETV/CPC. However, when assessing cases categorized as “other etiologies,” ETV was found to be more cost-effective per clinical unit, with an ICER of $60,061 compared to ETV/CPC ($93,350) and VPS ($142,135).

CONCLUSIONS

This study is one of the first attempts at quantifying the patient-level hospitalization costs associated with surgical management of hydrocephalus in pediatric patients treated in the United States. The results indicate that the conversation regarding CSF diversion techniques must be patient-specific and consider etiology as well as any previous surgical intervention. Again, these findings are short-run observations, and a long-term follow-up study should be conducted to assess the cost of treating hydrocephalus over the lifetime of a patient.
The long-term outcomes of endoscopic third ventriculostomy in pediatric hydrocephalus, with an emphasis on future intellectual development and shunt dependency
Authors: Hong Sukwoo , Hirokawa Daisuke , Usami Kenichi , Ogiwara Hideki
Published: November 2018

OBJECTIVE

The goal of this study was to clarify the long-term outcome of endoscopic third ventriculostomy (ETV) in pediatric hydrocephalus in light of the ETV Success Score (ETVSS), shunt dependency, and intellectual development.

METHODS

The authors retrospectively analyzed pediatric patients with hydrocephalus who underwent ETV between 2002 and 2012 and who were followed for longer than 5 years as a single-center cohort. The data of the patients’ pre- and postoperative status were collected. The relationships between ETVSS and the full-scale IQ as well as shunt dependency were analyzed. The usefulness of ETVSS for repeat ETV and the change of radiological parameters of ventricle size before and after ETV were also analyzed. The success of ETV was defined as no requirement for further CSF diversion procedures.

RESULTS

Fifty ETVs were performed in 40 patients. The average ETVSS was 61 and the success rate at 6 months was 64%. The mean follow-up was 9.9 years (5.2–15.3 years), and the long-term success rate of ETV was 50%. The Kaplan-Meier survival curve continued to show a statistically significant difference among patients with a low, moderate, and high ETVSS, even after 6 months (p = 0.002). After 15 months from the initial ETV, no patients required additional CSF diversion surgery. There was no statistical significance between ETVSS and the long-term full-scale IQ or shunt dependency (p = 0.34 and 0.12, respectively). The radiological improvement in ventricle size was not associated with better future educational outcome.

CONCLUSIONS

The ETVSS was correlated with the long-term success rate. After 15 months from the initial ETV, no patients required an additional CSF diversion procedure. The ETVSS was not considered to be correlated with long-term intellectual status.
A familial syndrome of hypothalamic hamartomas, polydactyly, and SMO mutations: a clinical report of 2 cases
Authors: Rubino Sebastian , Qian Jiang , Pinheiro-Neto Carlos D. , Kenning Tyler J. , Adamo Matthew A.
Published: November 2018

Hypothalamic hamartomas are benign tumors known to cause gelastic or dacrystic seizures, precocious puberty, developmental delay, and medically refractory epilepsy. These tumors are most often sporadic but rarely can be associated with Pallister-Hall syndrome, an autosomal dominant familial syndrome caused by truncation of glioblastoma transcription factor 3, a downstream effector in the sonic hedgehog pathway. In this clinical report, the authors describe two brothers with a different familial syndrome. To the best of the authors’ knowledge, this is the first report in the literature describing a familial syndrome caused by germline mutations in the Smoothened (SMO) gene and the first familial syndrome associated with hypothalamic hamartomas other than Pallister-Hall syndrome. The authors discuss the endoscopic endonasal biopsy and subtotal resection of a large hypothalamic hamartoma in one of the patients as well as the histopathological findings encountered. Integral to this discussion is the understanding of the hedgehog pathway; therefore, the underpinnings of this pathway and its clinical associations to date are also reviewed.
Characterization of grass pea (Lathyrus sativus L.) germplasm collections for the beneficial agronomic traits
Authors: Sarker Ashutosh , Rajendran Karthika , Singh Murari , El-Moneim Ali M.Abd , Nakkoul Hani
Published: November 2018

At ICARDA, germplasm collections obtained from five countries namely, Bangladesh, Ethiopia, Syria, Nepal and Pakistan were grouped in to seven sets of trials (BANG1,
BANG2, ICARDA, ETH1, ETH2, NEP, PAK) and evaluated in two experimental locations, Tel Hadya and Breda over eight years. Characterization was done for the most desirable agronomic traits such as days to first flowering, days to 95 % maturity, biological yield, seed yield, hundred seed
weight and Harvest index. Significant genotypic and interaction effect were found for the expression of the traits. Substantial amount of variability was revealed in the germplasm collections for most of the traits. High broad sense heritability was observed for days to first flowering and hundred seed weight indicating early phenotypic selection of these two traits. The stability over years for the seed yield (in terms of the CV), identified promising accessions such as ILG2178 in BANG1 and ILG1721, ILG1632, ILG1624, ILG1540 and ILG1501 for future breeding.
The usage of social media in marketing
communication of Croatian institutions of higher education
Authors: Jadrić Ivana , Kovačević Sandra
Published: November 2018

The importance and frequency of social media in marketing communication is undeniable today, especially when the target of such communication are young people (and the puropse is advertising and overall improvement of internal communication). Social media are the
main source of information for youth as well as virtual space where they can express and present themselves in the best possible way. The significant role of using social media in everyday communication has been recognized by institutions of higher education and they have become
an essential part of their marketing mix. Ultimately, the students are the ones who have the main role in acquiring new communication technologies and their communication networks have tendency to be dense and layered (Quan-Haase, 2007). That is the reason why new technologies like social media are mostly accepted and used by high school and university students. In this paper authors analyse the meaning, influence and usage of social media in the context of institutions of higher education and present the findings of an online survey conducted among teachers in such institutions in Croatia. By analysing the results, authors got 104 replies who helped them to get an insight into activities of institutions of higher education on social media as well as the usage of certain social media by private institutions compared with the public ones. This research confirmed that private institutions of higher education are on the overall more active in the usage of social media. However, Chi-squared test showed almost no difference in usage of the most popular social media Facebook and Instagram in private and public institutions of higher education, whereas there is a difference in usage of other social
media. In this research, the intensity of certain social media usage in general in Croatia was also compared with the level of their usage in institutions of higher education.
Actores y acciones: el liberalismo político en Michoacán (1851-1861)
Authors: Mercado Villalobos Alejandro
Published: November 2018

El objetivo de este trabajo es el examen del proceso de imposición del proyecto liberal en Michoacán. En él se buscar mostrar la manera en que, desde los actores y sus acciones, en la entidad se siguió la política de transformación nacional encabezada por Benito Juárez y el grupo de los liberales. Se aborda la cuestión a partir de tres momentos. El primero inicia con la exploración de un proyecto de reforma a las obvenciones parroquiales, presentado en 1851. Se continúa con el estudio de las intenciones por erigir un marco legislativo liberal luego de la Revolución de Ayutla. Para terminar con el análisis de la época del liberalismo radical, encabezado en Michoacán, por el general Epitacio Huerta.
VARIAN KEPESANTRENAN PADA PONDOK PESANTREN SYAECHONA CHOLIL BANGKALAN MADURA
Authors: Ahmad Abd. Kadir
Published: November 2018

Pergelutan pondokpesantren dengan realitas lingkungan yang mengitarinya terutama
seletelah Indonesia merdeka memperlihatkan dinamika yang beragam. Program pemerintah
melakukan upaya konvergensi sistempendidikanpesantren dengan diintrodusirnya sistem
madrasah, misalnya, menimbulkan berbagai varian. Di samping pesantren yang menerima, ada
juga yang tetap bertahan dengan tradisi semula di samping dan yang paling banyak adalah
kombinasi antara keduanya. Penelitian dengan menggunakan metode kualitatif dan historis di
Pondok Pesantren Syaechona Cholil (selanjutnya disingkat SC) di Bangkalan Madura adalah
salah satu pesantren yang tetap kukuh dengan sistem kepesantrenan meski tidak menolak sama
sekali sistem madrasah. Sikap resistensi itu paling tidak didorong oleh faktor historis dengan
simbol nama besar pendirinya, Kyai Cholil, budaya "ngaji" orang Madura, dan tuntutan akan
penyemaian kader ulama yang tak pernah surut.
PANDANGAN KEAGAMAAN GERE JA BETHANY INDONESIA
Authors: Ismail Arifuddin
Published: November 2018

This writing is a conclusion of research, that was conducted in Palu,
Central Sulawesi. This writing aims to describe the religious perspective
ofGBI (Gereja Bethany Indonesia), that was considered as a part of
fundamentalism movement on Christ.
The result of study showed that (1) the basic of religious faith of GBI is
God Jesus Christ, and confession that Jesus is messiest, the living Son of
God. (2) Bible is never wrong. The truth of Bible works at anywhere and
anytime. Men have to believe and do what Bible said. (3) Confession to
Apostle Creed. (4) The church is God institution to realize God in the
world. Church not only means as construction but also means as people
united to live in same faith, hope, and love to Jesus Christ. (5) The
movement of GBI emphasis to morality and spirituality especially to
young generation; (6) their motto is Successful Bethany Family
PERAN PARA SULTAN DALAM PENYEBARAN ISLAM DI GORONTALO
Authors: Sirajuddin Sirajuddin
Published: November 2018

This study aims to describe the role of royales in Former Gorontalo
Kingdoms. This study was conducted in Gorontalo. Data was collected
using interview and observation. Interview was conducted with local
Islamic Historician.
This Study Indicates that Islamic come into Gorontalo in several ways,
such are marriage, education, and politic. The role of Former Gorontalo
Royales was very important to Islamic diaspora in Gorontalo society.
The Kings that have main role are Sultan Amai, Sultan Matolodulakiki,
and Sultan Jogugu Eyato. The kings succesed to integrate Islamic value
into local tradition
HASIL PENELITIAN TENTANG REALITAS KEHIDUPAN SOSIAL DAN KEAGAMAAN MASYARAKAT NELAYAN (KASUS DESA MOSSO KECAMATAN SENDANA KABUPATEN MAJENE)
Authors: Kawu Abdul Shodiq
Published: November 2018

Sejak beberapa tahun terakhir ini, kajian
tentang wilayah pantai mendapat perhatian dari
banyak kalangan. Perhatian yang meningkat
ini terutama disebabkan oleh beberapa faktor.
Pertama, Indonesia adalah negara maritim
dengan wilayah laut yang luas, terutama lagi
dengan disepakatinya Konvensi Hukum Laut
Inlernasional, yant telah semakin memperluas
wilayah laut Indonesia. Wilayah laut yang luas
ini telah menyebabkan bahwa banyak kegiatan
ekonomi penduduk, khususnya mereka
yang bermukim di wilayah pantai, secara
langsung atau tidak langsung berkaitan dengan
pemanfaatan sumber daya laut. Kedua,
ada kesan pada sementara kalangan bahwa
kebijaksanaan ekonomi dan pembangunan
yang telah dilaksanakan selama tiga Pelita,
yang diprioritaskan pada pembangunan sektor
pertanian, temyata lebih banyak meneyentuh
dan menguntungkan wilayah-wilayah pedalaman.
Hal ini, antara lain terbukti dari kenyataan
bahwa dari berbagai kelompok
masyarakat di Sulawesi Selatan, kaum nelayan
yang menghuni wilayah pantai ini merupakan
kelompok masyararakat dengan tingkat penghasilan
paling rendah (Basri Hasanuddin,
1985:106).
ISLAM DI PULO TENGAH
Authors: Kawu Abdul Shodiq
Published: November 2018

Keadaan Fisik.
Pulo Tengah, salah satu dusun yang tcrletak
dalam wilayah Desa Amassang Kecamaian
Polewali Polmas. Terlctak ditengah pulau kccil,
dan terpisah dari daratan Bajoe, dacrah pesisir
pantai sebelah timur kota Kecamaian Polewali.
Untuk mencapai lokasi ini, bisa ditempuh lcwat
Binyang, dengan menggunakan perahu bermotor.
Pada umumnya pengunjung yang bcrminal
ke Pulo Tengah lebih suka melintasi pesisir
perkampungan Bajoe, dan menyebcrang ke sana
dengan perahu - perahu nelayan yang digunakan
untuk menaagkap ikan. Dari pesisir Bajoe ini,
Pulo Tengah dapat di jankau hanya sekitar 15
Menit dengan perahu motor kecil.
Dusun ini luasnya 300 hektar, terdiri dari
satu buah Rukun kampung, tiga RT dengan
jumlah penduduk 456 jiwa, Mereka tersebar di
Pulo ini, dengan membangun rumah - rumah
sederhana, model panggung. Pada umumnya,
rumah tempat kediaman penduduk dibangun
dari kayu, beratap rumbia. Secara geografis,
dusun ini, terisolir dari pusat aktiftas Desa
Amassangan. Sentuhan - senluhan pembangunan
fisik, sebagaimana yang sering terjadi di daratan
Desa tidak banyak menyentuh kepentingan
masyarakat
PERANAN SYARA' DALAM PROSES ALIHPERAN KB MANDIRI DI KABUPATEN GOWA
Authors: Ahmad Abdul Kadir
Published: November 2018

Penelitian ini dilakukan di tiga kecamatan
dalam Kabupaten Gowa, masingmasing
Kecamatan Sombaopu, Pallangga
dan Bontonompo. Kecamatan yang disebutkan
pertama merupakan wilayah kota
sesuai dengan posisinya sebagai ibukota
kabupaten dan berbatasan langsung dengan
kotamadya Ujung Pandang; sementara dua
kecamatan lainnya termasuk wilayah pedesaan.
Namun demikian, polarisasi ini
tidaklah ekstrim secara kultural, sebab sulit
untuk memberikan pembatasan antara "kota"
dan "desa" ketika proses transfonnasi budaya
berjalan hampir secara masal di kawasan
manapun pada era moderen sekarang ini.
POLA PEMBINAAN KEAGAMAAN NARAPIDANA DI LEMBAGA PEMASYARAKATAN SULAWESI SELATAN
Authors: Badrun Pat
Published: November 2018

Tulisan ini diangkat dari laporan hasil penelitian tentang Pota Pembinaan Kehidupan
Beragama Terhadap Narapidana di Berbagai Lembaga Pemasyarakatan di Sulawesi Selatan.
Penelitian itu sendiri dilaksanakan oleh Balai Penelitian Lektur Keagamaan Ujungpandang
bekerjasama dengan Badan Perencanaan Pembangunan Daerah (BAPPEDA) Tingkat I Sulawesi
Selatan dalam tahun anggaran 1994/1995. Sesuai dengan tujuannya maka hasil penelitian
telah mengidentifikasikan pola pembinaan kehidupan keagamaan yang dianggap standar serta
berlaku pada semua Lembaga Pemasyarakatan yang diteliti, serta aspeknya meliputi materi dan
metode pembinaan, sarana dan tujuan serta pencapaiannya, dan hambatan yang dihadapi dalam
pelaksanaannya. Laporan hasil penelitian telah dipresentasikan dalam seminar yang diadakan
oleh BAPPEDA Tingkat I Sulawesi Selatan dan disampaikan oleh Pat. Baclrun (penulis naskah
ini).
Desert Dreams of Drinking the Sea, Consumed by the Cold War: Transnational Flows of Desalination and Energy from the Pacific to the Persian Gulf
Authors: Low Michael Christopher
Published: November 2018

During the Cold War, from the early 1950s through the 1970s, the US Office of Saline Water was instrumental in spearheading the basic research and development that incubated the desalting techniques we see today. American technical assistance programs were fundamental to the growth of desalination capacity in the Middle East and its eventual globalisation. However, the federal government's original target for desalination was southern California and the arid Southwest. Desalination was proposed as the emergency backstop in the event that California's unquenchable thirst would inevitably overtax the dams of the Colorado River. And yet, American desalination never fully came to fruition. Instead, the promise of domestic desalination was co-opted and cannibalised by Cold War foreign policy. This essay traces how the Office of Saline Water's domestic desalination plans were repackaged and exported to Israel and Saudi Arabia. This essay considers how and why the United States slipped from the vanguard of desalination research while the Middle East emerged as its global leader. By connecting and comparing the divergent experiences of the American West and the Middle East, it also sheds new light on the nexus between the production of desalinated water and its key ingredient, energy.
THE USE OF COPPER INDICATOR ELECTRODES IN VOLTAMMETRIC ANALYSIS
Authors: Martynov L. Yu. , Naumova O. A. , Zaytsev N. K. , Lovchinovsky I. Yu.
Published: November 2018

The review describes the application of solid electrodes based on copper for voltammetric analysis of major classes of organic and inorganic substances over the last fifty years. Despite the fact that there are many reviews of individual solid electrodes this review offers the first comprehensive report on all forms of copper electrodes. The advantages and disadvantages of copper electrodes in comparison with electrodes made of other metals are discussed. Varieties of copper electrodes, their basic physico-chemical properties and some specific characteristics of their surface are described. The electrochemical behavior of copper in aqueous solutions and electrocatalytic mechanisms of transformations of matter on its surface are reported. Examples of the use of electrochemical copper sensors for flow-injection analysis and liquid chromatography are given. Recent trends of the use of copper micro- and nanostructured electrodes in electrochemical analysis are reviewed. The prospects of using copper as a material for the creation of new electrochemical sensors are shown.
Study on technology characteristics materials based on polysulfone
Authors: Baranov A. B. , Peksimov O. E. , Prudskova T. N. , Andreeva T. A. , Simonov-Emelyanov I. D. , Shembel N. L.
Published: November 2018

The research covers rheological characteristics of melts of polysulfones of domestic brand PSF-190 and foreign brand Udel P-1700 at temperatures ranging from 290 to 360°C. The values of activation energy of viscous flow of polysulfone melts at different temperatures are presented. The flow behavior indexes of melts of polysulfones PSF-190 and Udel P-1700 were determined. For the first time thermal stability curves over a wide temperature range were obtained, and formulas for describing them were presented. Temperature modes for processing the studied polysulfones were suggested. The dependency of density and volume in the temperature range from 23 to 320°C were obtained by the dilatometric method. Besides, constants and coefficients of the state equation of linear thermal expansion were calculated.
PENGARUH NORMA SUBYEKTIF,DAN TAM TERHADAP NIAT MENGGUNAKAN SISTEM ERP
Authors: Susilaputri Rizki Endah
Published: November 2018

ERP is a system used by the company to integrate all business processes. This study aimed to determine the effect of Subjective Norm and Technology Acceptance Model (TAM) of the Intention to Use ERP Systems. TAM in this study was measured by two indicators: Perception Perceived Usefulness and Ease of Use.Respondents in this study were users of ERP systems on PT. Semen Gresik (Persero), Tbk. Questionnaires were the primary data used in this research and random sampling was used as data collection method. Questionnaires were distributed about 70 copies but only 63 were returned, and 3 of them were incomplete questionnaires. The data analysis technique used was Partial Least Square, with the help of Smart PLS 2.0 software.The results of this study are: 1) Subjective Norms have positive significant effect on Intention to Use ERP Systems. 2) Perceived Usefulness have positive significant effect on Intention to Use ERP Systems. 3) Perceived Ease of Use have positive significant effect on Intention to Use ERP Systems.

DOI 10.5281/zenodo.1214920
Transaksi Ekonomi Klasik Masyarakat Aceh (Analisis Kelayakan Taqnin Hukum Ekonomi Syariah)
Authors: Fahriansah Fahriansah
Published: November 2018

Aceh is one of provinces in Indonesia (NKRI) granted special freedom to regulate households independently (formal juridical) in accordance with Islamic Shari'a. Islamic syariat covers about the economy. Economic activity in Aceh has special characteristics that are not against Islamic law, such as mawah, gala, and peublo aqad. Therefore, formal regulation is required to protect the business people and to safeguard Acehnese culture.

DOI 10.5281/zenodo.1214938
ANALISA STANDAR WAKTU TERHADAP KINERJA KARYAWAN CV. BETON AGARA KUTACANE
Authors: Nasruddin Nasruddin , Bu’ulolo Deliman
Published: November 2018

Identify the problem in this research whether the leader sets the standard of Work Time, Employee Performance Assessment, and What form of employee standard work. This research is qualitative descriptive, data collecting method with field research by using method, observation and direct interview on research object to get description of research subject. From result of research, obtained data and information, that leader set standard work time 8 (Eight) hours per day , provided that the company does not work on religious holidays, especially Islamic holidays. The standard of assessment carried out for the workforce is the objective standard, in which the management of the company has determined the unit of outcome of the working time used. To produce the Culvert for the size of 80.60, and 40 Cm standard of production objectives set by the company as much as, 36 units employing 6 (people) Labor, while for the size of 30.20, and 15 Cm, ​​employed 4 people with labor standard 45 Goal Units. Furthermore For Production Pavin Blok has 3 (Three) production type, Rectangle, Six and Nuts. Standard destination 1.800 Units, with 4 Persons labor, and other production is the Hole of the Wind that is Utuk Pagas and Layang, the workforce can produce as many as 80 Units, labor used 2 Person.
Synthesis and study on mechanical properties of the polypropylene/TiO2 - nano Ag composite for antibacterial application
Authors: Huynh Luan Nguyen Thanh , Huynh Cuong Chi , Ha Nhan Thuc Chi , Lam Vinh Quang , Le Hieu Van
Published: November 2018

In this study, PP/TiO2 – nano Ag composite were successfully prepared by melt mixing method. The composites TiO2 – nano Ag and PP/TiO2 – nano Ag with different silver content were characterized by scanning electron microscopy (SEM), Transmission electron microscopy (TEM), Xray diffraction (XRD) and IR spectrum to investigate their morphology and chemical compositions. It was found that the silver nanoparticles in TiO2 matrix were uniformly distributed and strongly attached to the polypropylene matrix and the average particle size of TiO2 – nano Ag was from 30 to 60 nm. As the result, the antibacterial property was obtained via microorganism test by showing the elimination of more than 99 % of E. coli bacteria. And UV protection behavior was also observed by UV-Vis characterization. In the other hand, the mechanical properties of polypropyleneTiO2-nano Ag composite were noticeably improved as compared to the neat polypropylene.
Respuesta de novillas Brahman a la sincronización del estro con progestagenos; conducta sexual y tasa de gestación
Authors: Silva-Mena Carlos , Guzmán-Casas Roberto , Delgado-León Roger , Aké-López Ricardo
Published: November 2018

Introducción. La sincronización del estro es muy útil para implementar programas de inseminación artificial, facilitar el manejo de los animales y agruparlos para el servicio. La información acerca del uso de este procedimiento en razas cebuinas (Bos indicus) es relativamente escasa.
Objetivo. Evaluar el efecto del tratamiento con progestágenos sobre la presentación del estro, la conducta estral y la tasa de gestación en novillas Brahman servidas con monta natural.
Material y métodos. Se usaron 64 novillas distribuidas en cuatro grupos de 16 animales y cuatro toros de la misma raza. Se sincronizó el estro con Norgestomet y valerato de estradiol y se registró la actividad sexual observada durante 30 horas entre las novillas y entre ellas y el toro. La gestación se diagnosticó 50 a 60 días después.
Resultados. Entre el 81.2 y el 100% de las novillas presentaron estro en los cuatro grupos. A partir de las 40 horas de retirados los implantes, el estro tuvo una duración promedio (± E.E.) de entre 8 ± 1 y 18 ± 1.4 horas en los cuatro grupos. La tasa de preñez fue de 37.5 a 71.4% en los cuatro grupos.
Conclusión. Se puede sincronizar el estro hasta en un 90%, en promedio, en novillas Brahman tratadas con Norgestomet + valerato de estradiol, con una duración e intensidad del estro variables y una tasa de gestación comparable con las observadas en hembras Bos taurus con tratamientos similares.
La duplicación de artículos en revistas médicas
Authors: J Castro-Sansores Carlos
Published: November 2018

En el número 2 del volumen 13 de la Revista Biomédica (abril-junio de 2002) se publicó el trabajo Clínica del Asma: ¿En realidad es útil?. Este mismo trabajo se publicó en la revista Alergia, Asma e Inmunología Pediátricasz en el volumen 11 número 2 (mayo-agosto de 2002). El contenido de ambos trabajos, si bien con algunas diferencias de estilo o cambios propuestos por los revisores, es el mismo.
Detección de HBsAg en muestras de sangre seca sobre papel filtro empleando el UMELISA HBsAg PLUS
Authors: Delahanty-Fernández Aurora , Valdivia-Alvarez Irina , Ventura-Paz Julio , Trujillo-Brito Janette , Ortega-León Darién , Palenzuela-Díaz Ariel
Published: November 2018

Introducción. Los enzimoinmunoensayo han sido empleados en la deteción de HBsAg empleando muestras de sangre seca sobre papel de filtro debido a las ventajas de este tipo de muestras ya que disminuye la utilización de materiales de laboratorios, este tipo de muestras pueden ser utilizadas en aquellos países donde los recursos son limitados para realizar estudios epidemiológicos.
Material y métodos. En este trabajo establecimos las condiciones óptimas para la elución de las muestras de sangre seca sobre papel de filtro con el fin de realizar la detección de HBsAg empleando el UMELISA HBsAg PLUS. Se evaluaron 1053 muestras de suero y sangre seca sobre papel de filtro procedentes de donantes de sangre de la Ciudad de la Habana, Cuba.
Resultados. En las muestras de suero se encontraron 9 individuos reactivos, de ellos 8 fueron confirmados como positivos por el ensayo confirmatorio HBsAg CONFIRMATORY TEST para un 0,75% de positividad y en las de sangre seca sobre papel de filtro 6 de las confirmadas fueron reactivos lo que representa un 0,57% de positividad.
Conclusión. Los resultados para ambos tipos de muestras fueron comparados y el índice Kappa fue de 0,85%, para una buena concordancia.
Evaluación de una prueba de ensayo inmunoabsorbente ligado a enzimas de competencia (ELISA-C) para el diagnóstico serológico de la brucelosis bovina
Authors: Dájer-Abimerhi Alfredo , J Gutiérrez-Ruiz Edwin , De las M Zapata-Villalobos Delfina , M Sierra-Lira Eduardo , I Cámara-Gamboa Elsie
Published: November 2018

Introducción. La brucelosis es una zoonosis a nivel mundial que además causa severas pérdidas a la ganadería por lo que es necesario tener pruebas de laboratorio específicas, sensibles y sencillas para establecer medidas de prevención y control efectivas.
Material y Métodos. Se probaron 724 sueros de bovino del banco del Depto. de Inmunología de la FMVZ-UADY, con un kit experimental de ELISAC. El punto de corte se determinó mediante un análisis ROC y una gráfica de dispersión. La concordancia entre la ELISA-C y Fijación de complemento (FC) se determinó con la prueba de Kappa. La sensibilidad y la especificidad se determinaron usando un cuadro de contingencia.
Resultados. El punto de corte (PC) encontrado fue de 47% de inhibición. La concordancia de la CELISA con relación a la prueba de FC fue de 0.80 para el total de sueros, 0.84 para sueros de animales no vacunados y de 0.72 para los vacunados. La sensibilidad fue de 92.27% (95% IC. 88.51-96.03) para el total de los sueros, 93.86% (95% IC. 89.45-98.27) para sueros de animales no vacunados y 90% (95% IC. 83.43-96.57) para los vacunados. La especificidad fue de 91.89% (95% IC. 89.56-94.21) para el total de los sueros, 94.26% (95% IC. 92.03-96.49) para sueros de animales no vacunados y 83.04% (95% IC. 76.08-89.99) para los vacunados.
Discusión. El punto de corte encontrado difiere del obtenido (30%) por el fabricante del Kit. La concordancia de la ELISA-C y FC fue alta pero su especificidad y sensibilidad con el PC de ›47% de inhibición, no la hacen una mejor prueba que FC; sin embargo, moviendo este PC se puede mejorar la especificidad o sensibilidad dependiendo de los objetivos de la campaña para el control/erradicación de la brucelosis bovina.
El caso de las publicaciones pornográficas y su acceso a niños y adolescentes en México
Authors: Quintanilla-Osorio Jesús
Published: November 2018

Es innegable en cualquier legislación que se precie de serlo, la garantía de expresarse libremente y sin cortapisas no existiendo nada que pueda medrar este derecho.
En la legislación mexicana, el artículo séptimo de la Constitución Política, permite al ciudadano común, expresarse libremente y bajo la protección del estado, siempre y cuando no vulnere los derechos de terceros, porque entonces, si existe la probatoria de incurrir en un acto doloso que pueda afectar a un ciudadano, este puede esgrimir en su defensa, la denuncia por difamación de honor.