bluuebunny/crossref_metadata_2025 huggingface dataset:
Isolation and Identification of Antioxidant Compounds from Stained Pyrus serotina Fruit Extract for alternative tea development
Authors:   Association for International Tea Culture, Jeon Hyeong-Ju , Lee Seung-ho
Published: November 2022

For alternative tea development, 2 kg of dried stained Pyrus serotina was extracted with 70 % MeOH aqueous solution, and the extract was solvent-fractionated with EtOAc, n-BuOH and Water. Two types of bioactive compounds were separated from the EtOAc fraction, by purification with silica gel and octadecyle silica gel (ODS) column chromatography. The chemical structure of the compounds were identified as quercetin (1) and geniposide (2) by analyzing spectral data with NMR, MS and IR. For the evaluation of antioxidant activity, DPPH inhibitory efficacy test and ROS production inhibitory efficacy test were performed. First, as a result of measuring the DPPH inhibitory efficacy of two samples up to the highest concentration of 50 ppm in the DPPH inhibition efficacy test, the IC50 values of NICS-1 and NICS-2 were measured to be 25.554 ppm and 22.943 ppm, respectively. In ROS production inhibitory efficacy test, the ROS production was reduced in a concentration-dependent manner in both samples, and statistically significantly inhibited ROS production compared to the UV irradiation group. According to recent reports, this study is expected to develop eco-friendly sustainable health drinks using pears and cheese and functional raw materials using pears and teeth through organic cosmetics.
A Study on Hanjae's 『Dabu(茶賦)』 Writing birth and Writings place
Authors:   Association for International Tea Culture, Kim Jang-hwan
Published: November 2022

The purpose of this study is to examine the writing date and journal of 『Dabu』 by Hanjae Lee Mok (寒齋 李穆, 1471-1498). Hanjae ended his short life at the age of 28 by being sentenced to death for being involved in the sacrificial affair. 『Dabu』 was published in 1585 by his grandson Cheol (鐵), who was the governor of Musong-hyeon, a print book called 『Lee Pyeongsajip(李評事集)』, and in 1981 by the Hanjae Clan Management Committee, a Korean translation 『Hanjaemunjip (寒齋文集)』 was published. became known in the tea world. However, errors are being discovered as his life and chronology are added 483 years after his death. Therefore, it is necessary to interpret and understand 『Dabu』 by examining the writing date and journal of 『Dabu』 by Hanjae. Therefore, after reviewing the previous studies, we intend to examine the writing date and journal of 『Dabu』 by comparatively analyzing the scenery of  and 『Dabu』 based on the new exile data.
Tourist destination competitiveness and ESG performance in the airline industry
Authors: Dempere Juan , Modugu Kennedy
Published: November 2022

The relevance of corporate environmental, social, and governance performance (ESG) has increased significantly during the last few years. The airline industry is susceptible to such environmental, social, and governance practices, which explains its selection for the analysis purposes in this study. This paper analyzes the influence of the Travel & Tourism Competitiveness Index and its constituent factors on environmental, social, and governance performance variables in a sample of leading airline companies worldwide with historical data available from 2013 to 2019. The study required analyzing panel data using a panel-corrected standard error model. The results suggest that airlines headquartered in countries with ideal conditions for operating businesses and outstanding information and communication technology readiness show excellent environmental, social, and governance performance. However, the findings also imply that airline companies headquartered in countries with heavy government influence on the airline industry sector measured by the government prioritization of the domestic travel and tourism sector have poor environmental, social, and governance performance. Similarly, the analysis provided evidence that countries well positioned to join national air service arrangements and subscribe to regional trade agreements have airline companies with excellent environmental, social, and governance performance metrics. The reported results can be priceless for policymakers designing national travel and tourism policies to enhance domestic airline firms’ environmental, social, and governance performance.
Mathematical Mapping Study of Synthetic Antioxidants Behavior in Biodiesel: Application of the Self-Organized Feature Map (SOFM) and Multilayer Perceptron (MLP)
Authors: Clemente Marco , Silva Heloisa , Campos Julia , Silva Nathan , Sousa Eduardo , Mantovani Ana , Angilelli Karina , Borsato Dionisio
Published: November 2022

The objective of the present work was to apply self-organizing feature maps (SOFM) and multilayer perceptron (MLP) to evaluate the protective capacity of tert-butylhydroquinone (TBHQ), butylhydroxyanisole (BHA), and butylhydroxytoluene (BHT) antioxidants against the biodiesel oxidation reaction. For this, the antioxidant concentration and the biodiesel compliance parameters were used as continuous input variables and the type of antioxidant as a categorical. The SOFM proved to be an adequate tool for the classification of biodiesel samples containing antioxidants. The performance of the 5 most active networks of the model ranged from 89 to 99% for training, testing, and validation with an error below 1.42 × 10-4. Statistical tests applied to validate the model showed no significant difference between predicted and experimental values. The global sensitivity analysis showed that the relative protection factor (RPF) contributed with 34.89%, the antioxidant with 31.49%, the induction period with 10.69%, the water content with 6.00%, and the others all together with 16.93% in the construction of the regression models by MLP.
Distribution Pattern of Refugia and Horticultural Plants in Three Areas of Pamekasan Regency
Authors: Sufiyanto Mohammad Imam , Hefni Mohammad , Aflahah Aflahah , Kamaroellah R. Agoes
Published: November 2022

This study aims to determine the types of refugia and horticulture plants in the Pakong, Pegantenan, Pasean areas in Pamekasan Regency, as well as the factors that influence the diversity of these barrier and horticultural plants. This research is descriptive in nature: Direct observations in three areas in Pamekasan Regency with the roaming method or exploring the area of the area. Descriptive qualitative analysis data found that barrier plant species were found in one class, namely: Dicotyledonae and order three, namely: Malvales, Fabaceae, Pedialiaceae, while for horticultural plants there were two classes namely Monocotyledone and dicotyledone and five orders namely Malvales, Arecaceae, Oleaceae, Sapindaceae, and Malphigiales. Abiotic factors in three areas, namely: Average temperature 6,5, air temperature around 31,7o C, humidity with an average range of 7.4% and the light intensity ranges from an average of 1120lux.
Elemental Composition of Tagar Copper-Bronze Sickle-Shaped Tools
Authors: Savel’eva A. S.
Published: November 2022

The article features the elemental composition of copper and bronze sickle-shaped tools of the Tagar culture. The structure and composition of metal sickles have been the focus of chemical and spectral quantitative analyses since the 1950s. The paper introduces new data obtained by X-ray fluorescence, energy dispersive, and atomic emission spectral methods. The chemical and chemical-metallurgical features of the alloys add to the external descriptions of the Tagar metal tools. The research objective was to identify the features of Tagar copper-bronze sickles based on the chemical-metallurgical profile of the alloys. The authors also analyzed the effect of the alloy formulations on the morphological and metric characteristics of the tools, compared the bronze formulations with surface patterns, and established the copper ore sources. The study revealed no relationships between the bronze formulations and the morphological and metric indicators. An attempt to search for correlations showed two types of sickle-shaped tools. By measuring the length of the base and the height of the blade, the authors restored the actual sickles and reaping knives. The second type tools came from the Mariinsk-Achinsk foreststeppe. An analysis of the geochemical impurities in high-concentration copper indicated that the ore used in the Tagar tools was similar to that mined in the Glafirinsk and Kharadzhul-Butrakhty mines in the eastern foothills of the Kuznetsk Alatau. The sickle-shaped tools might also have been used to harvest fodder for livestock.
Military Corps of the Kuznetsk District in the First Half of the XVIII Century: Staff, Manpower, and Occupation in the Context of Regional Administrative Processes
Authors: Bobrov D. S.
Published: November 2022

The article features the staff, manpower, occupation, and subordination issues in the military corps of the Kuznetsk district in the fi st half of the XVIII century. Th frontier exploration into the southern border regions of Western Siberia caused administrative transformations in the region. The research relied on management and accounting documentation from the Russian State Archive of Ancient Acts. Th author reviewed the structure of the service activities of the irregular military corps, which included both ordinary assignments to the border area for riverside patrol and extraordinary assignments for the construction of new fortifications. The Kuznetsk authorities did their best to reduce the administrative burden. The archival documents prove that the actual number of the military people in the district reduced as a result of the changes in the military, political, and management situation. By the mid 1740s, the local civil authorities had completely lost administrative control over the military staff, which passed into the hands of military departmental structures.
Provincial Budget and Agronomic Assistance in the Tomsk Province in the Late XIX – Early XX Centuries
Authors: Pocherevin E. V.
Published: November 2022

The article presents the history of planning, discussion, and approval of the Tomsk provincial budgets by the central departments in the early XX century. The analysis included documents on preparation and adoption of three-year estimates and revealed a high degree of interest in agrarian transformations, both on the part of the local population and the provincial administration. The appropriations approved and implemented in practice included the allocation of funds for dairy experts and experimental farms. However, the budgets drafted by the provincial administration faced significant restrictions from the central departments as a result of the poor legislative grounds. While planning the draft budget for 1915–1917, the Tomsk provincial agronomist put forward a large-scale project for agricultural development, which included a big experimental station. The proposals were discussed by the local committees and received a mixed assessment, e.g., the Biysk committee supported the plan, but the Zmeinogorsk committee was very skeptical about it. Despite the considerable preparatory work, the central department reduced the final version of the provincial budget by 53%.
Allegorical Images in The Gray House by Mariam Petrosyan
Authors: Sinegubova K. V.
Published: November 2022

This article discusses the strategies of visual representation and the status of visual images in Mariam Petrosyan's novel The Gray House, originally published in Russian as The House in Which... The novel is an excellent example of magical realism in contemporary literature. Dispersed throughout the text, visual images have an important role in understanding the fictional world. The characters of the novel sketch animals or fantastic creatures, which become their signatures. The pattern is similar to that of a magical ritual. These drawings and graffiti help the characters to communicate with the mystical House, where they all live. The drawings represent someone or something, while being themselves the subject of representation, which complicates the structure of the novel and requires readers’ reflection. The allegorical nature of the drawings creates the semantic continuity of the House because the characters share the same way of self-expression. The images created by Smoker are special because this character belongs to the House only partially. Smoker’s drawings clearly demonstrate his alienness in the world of the House, but they provide a metaphorical understanding of the House and offer its artistic interpretation. They serve as an alternative key to deciphering the mystical nature of the space. Smoker’s drawings reveal the concept of time distorted by the House
Geospatial assessment of early summer heatwaves, droughts, and their relationship with vegetation and soil moisture in the arid region of Southern Punjab, Pakistan
Authors: Arshad Sana , Kazmi Jamil Hasan , Shaikh Saima , Fatima Munazza , Faheem Zulqadar , Asif Muhammad , Arshad Waqar
Published: November 2022

This study focuses on the spatiotemporal analysis of early summer heatwaves, droughts, and their relationship with vegetation and soil moisture from 2013 to 2022 in South Punjab, Pakistan. The study uses a unique approach of utilizing a combination of meteorological-based maximum air temperature Tmax derived from Modern-Era Retrospective analysis for Research and Applications V.2 (MERRA-2) and remotely sensed land surface temperature (LST) to calculate heatwave metrics. Station-based precipitation (P) and remote sensing-based temperature condition index (TCI) are utilized to calculate droughts. The normalized difference vegetation index (NDVI) and the normalized difference water index (NDWI) are used to analyze the relationship between extreme events with vegetation and soil moisture. The results reveal a significant rise in the region's heatwave frequency, duration, and intensity. Spatiotemporal analysis of the SPI and TCI shows the occurrence of droughts in more heatwave years. Negative Pearson correlation R = 0.5–0.9 and coefficient of determination R2 of 0.76–0.86 of the NDVI and NDWI with drought and heatwave metrics represents a significant (<0.01) relationship and direct response of vegetation and soil moisture towards extreme events. The study affirms the hydrological vulnerability of arid regions due to extreme events and marks the attention to appropriate mitigation and adaptation strategies in the future.
OPTIMIZATION OF THE PLANT ILLUMINATION SYSTEM STABILIZING OXYGEN CONCENTRATION IN THE GAS MEDIUM WITHIN A PROTOTYPED BIOTECHNICAL CREW LIFE SUPPORT SYSTEM
Authors:   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Berkovich Yu.A. , Shalopanova О.А. ,   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Buriak А.А. ,   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow
Published: November 2022

We validated an approach to optimization of the higher plant illumination system within a biotechnical life support system (BTLSS) in order to reduce power consumption and equivalent harvest mass. The challenge was to stabilize oxygen concentration in the air of a pressurized compartment. To compare different approaches to power consumption optimization, we used publications on a study in which BTLSS with a 27 m2 cultivation area provided leaf vegetables (Chinese cabbage) to 2 human subjects. Time course of the daily energy and O2 consumption was divided into 5 periods according to specified levels of loading. In context of a Moon mission scenario, the optimal photon flux density and white-red light ratios were calculated using regression models for each day between vegetation days 8 and 14. Experimentally obtained models of photosynthetic productivity were used to calculate a daily lighting level required to produce oxygen in the amount sufficient for the crew. It was shown that this method of O2 stabilization makes possible, within 7 days, power consumption reduction by 68 % and increase of the coefficient of light energy consumption by harvest in 2.3 times as compared to the control growing under continuous invariable illumination. Moreover, equivalent mass of the illumination system reduced 30 % as compared to the control.
IMITATIVE VIRTUAL REALITY-BASED MODELING OF THE MODES OF PILOTED VEHICLE CONTROL ON A LUNAR STATION TO INVESTIGATE OPERATOR'S ACTIVITY IN ISOLATION STUDIES
Authors:   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Bubeev Yu.A. , Usov V.M. ,   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Polyakov A.V. ,   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Mikhaylyuk М.V. ,   Federal State Institution «Scientific Research Institute for System Analysis of the Russian Academy of Sciences», Moscow
Published: November 2022

The survey is focused on the applicability of virtual reality(VR) and 3D immersive technologies for isolation studies of the human-robot interaction during intravehicular activities (IVA) and scenarios of pilotless vehicles (PVs) operations on a lunar station. The investigation resulted in covering the prototyped multicopter drones for inspecting closed environments on Earth and future creation of appropriate VR models, and proposing off-line PVs analogous to the NASA Free-Flyers Units Astrobee, and VirSim system for use on the lunar station. The imitative VR models and suggested research tasks include the following: 1) PVs scenarios, routing and scheduling, 2) modeling autonomous navigation and control (local positioning and navigation) inside the station, 3) manual piloting, 4) virtual and real control panels, 5) comparison of displays representing PVs cameras stream, 2D-electronic maps and real-time 3D-image, 6) PVs scenarios for potential danger to the lunar station, and support of response to unexpected events. Knowledge from the isolation studies can substantiate guidelines on PVs operations aboard habitable lunar stations.
PERSPECTIVES OF PSYCHOLOGICAL SUPPORT IN FUTURE EXPLORATION MISSIONS
Authors:   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Gushchin V.I. , Ryumin O.O. ,   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Karpova О.I. ,   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Rozanov I.A. ,   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Shved D.M. ,   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Yusupova A.K. ,   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow
Published: November 2022

The paper summarizes the experience of providing the psychological support for orbital space crews, discusses current practices applicable in future exploration missions, and the psychological negative factors in autonomous missions including new promising technologies developed with these factors in mind.
ROLE OF AMP-ACTIVATED PROTEIN KINASE IN REGULATION OF CALCIUM-DEPENDENT AND UBIQUITIN/PROTEASOME SIGNALING PATHWAYS DURING MUSCLE FUNCTIONAL DISLOADING
Authors:   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Belova S.P. , Zaripova К.А. ,   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Sharlo К.А. ,   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Shenkman B.S. ,   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Nemirovskaya T.L. ,   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow
Published: November 2022

We tested the hypothesis that in unloaded skeletal muscles the calcium-dependent signaling pathways and E3-ligase expression are controlled by regulation of phosphorylation of AMP-activated protein kinase (AMPK). For a 3-d experiment 32 Wister male rats were divided into 4 groups: placebo control (С), metformin control (300 mg/kg of body, per oral, MC), suspension and placebo (SP), suspension and metformin (SM). Object of the investigation was m. soleus. In comparison to group C, rAMPK in group MC reduced 46 % and ATP increased 49 % (p < 0.05); pCaMK II showed an increase and expression of mRNA CaN, SERCA2a and Calpain 1 grew 483 %, 87 %, 41 % and 62 %, respectively; p < 0.05). In group SP, MuRF1, MAFbx E3-ligase expression and ubiquitin increased 167 %, 146 % and 191 %, respectively (p < 0.05). Per oral metformin prevented these changes in the suspended rats. During 3 days of suspension, metformin prevented changes in rAMK and ATP; also, it influenced regulation of the calcium-dependent signaling pathways through expression and phosphorylation of such markers as CaMK, CaN, SERCA2a and Calpain-1, and prevented to a degree growth in expression of key markers of ubuquitin-proteasome pathway – MuRF1, MAFbx, and uniquitin.
PARAFUNCTIONS OF THE MASTICATION MUSCLES IN AIRLINE PERSONNEL: FREQUENCY OF OCCURRENCE AND PATHOGENESIS (CLINICAL EXPERIMENTAL INVESTIGATION)
Authors:   International Academy of Sciences of Ecology, Human Safety and Nature (IASEHS), St.-Petersburg, Iordanishvili А.К.
Published: November 2022

The paper reports the results of a clinical experimental investigation into occurrence and pathogenesis of masseter parafunctions in several groups of airline personnel. Painless masseter parafunctions diagnosed in 12.4–20.5 % of the air personnel led to pathological dental abrasion or aggravation of chronic generalized parodentium. Parafunctions are often the case among helicopter pilots (20.5 %) and fighter pilots (18.9 %) and accountable to the effects of chronic vibration and hypergravity which are much stronger than in civil and military transport aviation. The investigation showed that pathogenesis of the masseter parafunctions arises from disorders in blood supply, muscular tissue hypoxia and transcapillary exchange. Changes in the intensity of fluorescence of the adrenergic nerve fibers and acetylcholinesterase activity due to repeated exposure to hypergravity and vibration may evidence pathogenetic developments in the mastication muscles and be the reason of increased fatigability among helicopter and fighter pilots.
Preliminary screening of a hexapeptide combinatorial library for glucosyltransferase (GTF-I) inhibition
Authors: Mooser Gregory , Devulapalle Kumari S.
Published: November 2022

Glucosyltransferases from oral bacteria are significant virulence factors in dental caries initiation. An L-aminoacid synthetic peptide combinatorial library was synthesized and screened for its ability to inhibit the glucosyltransferase activity. One inhibitory hexapeptide was identified to determine the dissociation constant.
Preliminary crystallographic study of two crystal forms of rubredoxin from sulfate­ reducing bacterium
Authors: Higuchil Yoshiki , Misaki Shintaro , Sugiyama Shigeru , Morimoto Yukio , Ogata Mari , Yagi Tatsuhiko , Yasuoka Noritake
Published: November 2022

Two crystal forms, Form I and Form II, of rubredoxin from Desulfovibrio vulgaris Miyazaki F have been obtained by microdialysis and vapor-diffusion methods. The Form I crystals are in space group of P3221 with a=b=43.7, c=50.7A, whereas the Form II in space group ofP2, with a=27.3, b=44.9, c=Sl.2A, and /3=90.6°. Crystals in both crystal forms diffract at least 2.0A resolution.
Posttransplant Diabetes Mellitus (PTDM) Following Solid Organ
Transplantation - Systematic Analysis of Prevalence and Total Mortality
and Meta-Analysis of Randomized Interventional Studies Aimed at Lowering
Blood Glucose
Authors: Almdal Kerstin , Hornum Mads , Almdal Thomas
Published: November 2022

Objective:

A systematic review of the prevalence and prognosis of posttransplant diabetes
mellitus (PTDM) following the transplantation of heart, lung, liver and kidney and a metaanalysis
of randomised studies of glucose-lowering treatment is reported.

Methods:

We searched for publications on solid organ transplants and PTDM in relation to the risk
and total mortality of PTDM and randomized controlled trials aiming at reducing glucose levels.

Results:

PTDM prevalence one year after transplantation was reported to be 9-40%. Ten years after
transplantation, 60-85% of people without PTDM and 30-76% of people with PTDM were
alive. Following kidney transplantation, we identified six randomized controlled trials on the
treatment of PTDM. Intervention ranged from 3 to 12 months. Four studies used intervention with
oral glucose-lowering drugs, one used dietician appointments and exercise, and one used insulin
treatment. Among the intermediate results reported, a reduction in HbA1c of 2.7 mmol/mol, and an
increase in the odds ratio of serious adverse events of 3.0 was significant.

Conclusion:

In conclusion, information on the prevalence and effect on survival of PTDM is heterogeneous,
and the randomized studies on the effect of treatment available are short and lack information
on clinically important endpoints, such as mortality or morbidity.
Recent Patent for Walking Device of Corn Harvester
Authors: Bao Yudong , Zhang Jianlong , Zhao Yafei
Published: November 2022

Background:

Corn harvesting is an important part of the entire corn production process.
Corn harvester power, turning radius and dehulling device will directly affect harvest efficiency and
the quality of harvested corn. Obtaining better performance peeling device with strong power and
minimum turning radius is the research direction in this field.

Objective:

This paper summarizes the patents of the walking system of corn harvesters at home and
abroad in recent years, and introduces the characteristics and development of knapsack harvesters,
trailed harvesters and self-propelled harvesters, such as power, turning radius and artificial intelligence.
summarize its development trend, and provide reference for the development of various aspects
of crop harvester.

Methods:

This paper reviewed the research status of the corn harvester walking system in recent
years, and discussed the structure types and applications of various harvester walking systems.

Results:

By summarizing the patents of the walking system of the corn harvester, this paper obtains
the current patent application status, analyzes the main problems in its development, and discusses
the problems existing in the walking system of the harvester and the future research direction.

Conclusion:

The running device of the existing harvester needs to be further improved in terms of
reliability, power system, turning radius, etc. The patent of the walking device of the harvester is yet
to be developed. With the application of GPS, sensing and detection, information processing, automatic
control and other technologies in the field of harvesting, the mechanized corn harvesting is
gradually developing towards intelligence and automation.
Errors of using Balinese in Awig-Awig
Authors: Sujaya Nyoman , Laksmi A. A. Rai Sita , Sukiani Ketut , Winaya Made Detrichyeni
Published: November 2022

This paper accounts for the errors of using Balinese in Awig-awig. It focuses on kinds and causes of errors found in the Awig-awig as regulations of the Balinese traditional villages. Using the data taken from the Awig-awigs of Munggu, Beringkit and Sobangan traditional villages, and applying the theory of error analysis by Richard as well as adopting the thought of linguistics knowledge from Van Valin and Randy (1999) and Warna (1983), it was found that there were three kinds of errors of using Balinese in the data. They involve: phonological, morphological and syntactical errors. The syntactical errors cover illogical sentences, ineffective sentences, addition, omission and errors in parallelism. The errors were mostly caused by the lack of language competence on linguistics of the writers.
Word-level spelling of children with dyslexia and developmental language disorder
Authors: De Bree Elise , Lammertink Imme , Van Witteloostuijn Merel , Rispens Judit
Published: November 2022

Veel kinderen met dyslexie en met een taalontwikkelingsstoornis (TOS) hebben moeite met spellen. Het is niet bekend of deze problemen hetzelfde zijn voor beide groepen,omdat er weinig directe spellingvergelijkingen tussen deze twee groepen kinderen zijn gemaakt. In deze studie vergeleken we de woorddictee-uitkomsten en foutenpatronen van kinderen (leeftijdsrange 8.2-10.4 jaar) met dyslexie (n=31), TOS (n=30) en een leeftijdsgematchtecontrolegroep (n=31). Daarnaast verdeelden we de TOS-groep in kinderen met TOS met leesproblemen (TOS+LP, n=18) en zonder leesproblemen (alleen-TOS, n=12). Tot slot voerden we regressieanalyses uit om te bepalen welke taal- en lees(gerelateerde) vaardigheden invloed hebben op spellingsuitkomsten.Zowel de dyslexie- als TOS-groep vertoonden spellingproblemen. Deze waren het meest uitgesproken voor de TOS+LP-groep. Wat betreft foutsoorten maakten de dyslexieenTOS-groepen meer fouten in alle categorieën dan de controlegroep. De dyslexie, alleen-TOS en TOS+LP-groepen lieten eenzelfde patroon zien wat betreft het spellen van woorden met foneem-grafeemassociaties die niet helemaal klankzuiver zijn (gauw als *gouw), met woorden waarin fonologie-orthografie-en morfologie moeten worden gecombineerd (pittig als *pitteg) en met regelwoorden (metro als *meetro). De dyslexieen TOS+LP-groepen lieten ook meer fouten zien in klankzuivere foneemgrafeemkoppelingen(boek als *beok) en met orthografische kennis (leenwoorden). De regressieanalyses lieten een sterke bijdrage zien van woordlezen en snelbenoemen aan woordspelling. Regressieanalyses zonder deze lees(gerelateerde) vaardigheden lieten een beperkte bijdrage van morfologie zien aan de spellingsuitkomsten.Deze resultaten bevestigen dat kinderen met dyslexie en TOS spellingprobemen hebben, zeker kinderen met TOS+LP. Ze wijzen naar de belangrijke bijdrage van woordleesvaardigheiden snelbenoemen voor spellen, en een beperktere bijdrage van morfologie.

Samen geven ze de noodzaak weer van systematisch spellingonderwijs en ondersteuning voor kinderen met dyslexie en TOS, alsook het belang van mondelinge taalondersteuning.Trefwoorden: Spelling, Dyslexie, Taalontwikkelingsstoornis, Lezen, Taal.
Influence of high pressures on the formation of new phase in the Al-=SUB=-86-=/SUB=-Ni-=SUB=-2-=/SUB=-Co-=SUB=-6-=/SUB=-Gd-=SUB=-6-=/SUB=- alloy
Authors: Menshikova S. G.  , Brazhkin V. V.
Published: November 2022

The structure, elemental and phase composition of the eutectic alloy Al86Ni2Co6Gd6 (hereinafter referred to as at.%) During the solidification of the melt from 1500oC at a rate of 1000oC/s under high pressure of 3 and 7 GPa have been investigated by X-ray diffraction analysis and electron microscopy. Solidification of the melt under high pressure leads to a change in the phase composition of the alloy and the formation of an anomalously supersaturated solid solution of α-Al(Gd). At a pressure of 7 GPa, new phases were synthesized: Al3Gd* (like Al3U) containing Co and Ni, with a primitive cube structure (cP4/2) with a lattice parameter a=4.285±0.002 Angstrem and Al8Co4Gd* (like Al8Cr4Gd) with a tetragonal structure (tI26/1) with parameters a=8.906±0.003 Angstrem and c=5.150±0.003 Angstrem. The structure of all the samples obtained is homogeneous, dense, finely dispersed, without shrinkage cavities and pores. The average microhardness of the samples is high due to solid solution and precipitation hardening. Keywords: high pressure, microstructure, phase, microhardness, melt.
New Heat and Moisture Exchangers for Laryngectomized Patients in Germany: Mixed Methods Study on the Expected Effectiveness
Authors: Ahmed Anam , Mewes Janne C , Boot Iris W A , Vrijhoef Hubertus J M
Published: November 2022

Background

Notwithstanding the benefits of heat and moisture exchangers (HMEs) in both clinical research and practice, a gap exists between the optimal physiological humidification created through the nasal function and the humidification capacity of HMEs for patients after total laryngectomy. In this study, 5 new HMEs (Provox Life) specialized for situational use with improved humidification capacities were evaluated.

Objective

This study aims to evaluate the effectiveness of the existing HMEs, assess the potential effectiveness of the new HMEs, and elicit expert judgments on the new HMEs’ expected effectiveness and impact on health care use.

Methods

First, a rapid literature review (RLR) was performed to identify evidence on the clinical outcomes, health outcomes, and complications of HMEs in patients who underwent laryngectomy. Second, semistructured interviews with German experts (n=4) were conducted to validate the findings of the RLR and identify reasonable expectations regarding the potential of the new HMEs. Third, a structured expert elicitation among German experts (n=19) was used to generate quantitative evidence on the expected effectiveness of the new HMEs in clinical and health outcomes.

Results

The RLR (n=10) demonstrated that HME use by patients has advantages compared with no HME use concerning breathing resistance, tracheal dryness and irritation, mucus production and plugging, frequency of cough and forced expectorations, sleep quality, voice quality, use of physiotherapy, tracheobronchitis or pneumonia episodes, quality of life, and patient satisfaction. From the expert interviews and structured expert elicitation, it was found that, on average, experts expect that compared with the second-generation HMEs, the new HMEs will lead to a decrease in tracheal dryness or irritation (51%, SD 24%, of patients), mucus plug events (33%, SD 32%, of patients), mucus production (53%, SD 22%, of patients), physiotherapy (0.74, SD 0.70, days) and pulmonary infections (34%, SD 32%) and an increase or improvement in speech quality (25%, SD 23%, of patients), social contacts (13%, SD 18%), quality of life (33%, SD 30%), and patient satisfaction (44%, SD 30%). An improvement in breathing (53%, SD 28%, of patients) and shortness of breath (48%, SD 25%, of patients) was expected. The average number of daily cough periods and forced expectorations was expected to be 2.95 (SD 1.61) and 2.46 (SD 1.42), respectively. Experts expect that, on average, less than half of the patients will experience sleeping problems (48%, SD 22%) and psychosocial problems (24%, SD 20%).

Conclusions

According to German experts, it is expected that the new HMEs with improved humidification levels will lead to additional (clinical) effectiveness on pulmonary health and an improved overall quality of life of patients compared with the currently available HMEs.
From Isolation to Inclusion: How the Charter Changed our Perceptions of Being and Belonging
Authors: Das Satya Brata
Published: November 2022

The Canadian Charter of Rights and Freedoms is an indispensable catalyst in shaping Canadian identity, forming a rich and diverse mainstream that integrates and intermingles many streams of human experience. The idea of Canada and what it means to be Canadian is dynamic and evolving, empowered by a Charter that arguably for the first time recognized and affirmed Indigenous peoples as the founding nations of Canada, and nurtured a sense of inclusion that promoted unity in diversity. Just as emergence from the Covid-19 pandemic has been a journey from isolation to inclusion, so has the forging of Canadian identity since the adoption of the Constitution Act, 1982. Drawing from stories shared in a circle aux batons-rampus, and from observations from a four-decade career as a public intellectual, I argue that Canadians’ evolving sense of being and belonging, brought into even sharper relief by the Covid-19 pandemic, is shaped by a Charter which embraced both individual and collective rights.
El tejido adiposo, ¿solo un almacén de energía?
Authors: Milán Chávez Rebeca , Morales-García Norma Liliana , Morales-López Sara , Rojas Lemus Marcela , Fortoul Teresa I.
Published: November 2022

Whenfoodmeetsenergyrequirements, thebodystores in theliver and in themuscletheexcessofcalories as glycogen and triacylglycerols in the adipose tissue. Morphologically and functionally, itisclassifiedintowhite and browntissues. Brown tissue has manylargemitochondria and storestriacylglycerols in vacuoles and dissipatesenergy as heat; whitetissuestoresenergy as lipiddropletsthatoccupymostoftheadipocyte’svolume. After foodintakeinsulinisreleased, which causesGLUT4 externalizationintothecellularmembranetoabsorbglucose. Chylomicronsor VLDL transporttriacylglycerolsto adipose tissuedepots. Duringfasting, bytheactionofglucagon, enzymes are releasedthatwill degrade tri-, di- and mono-glycerolstoreleasefattyacids. Adipose tissuereleases pro and anti-inflammatorycytokines, as well as leptin and adiponectinthatregulateappetite and satiety. AMPK isactivated in response to a decrease in thecell’senergy and helpsittomaintainitsenergetic balance. In theadipocyte, itpromotesthedegradationoftriacylglycerolsreleasingfattyacidsto be used as anenergysource. More studies are neededtolearn more aboutthefunctionof adipose tissue as a regulatorofthemetabolism and notonly as anenergystorage. Keywords: Adipocyte; brown adipose tissue; white adipose tissue; GLUT4; triacylglycerol; AMPK.
The meaning of work in agricultural education in Practical arts interpreted based on J.pieper's concept of ‘Schole’
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, GO IN GYU
Published: November 2022

Objectives This study was conducted with the aim of establishing the meaning and value of work in career education through the exploration of Schole's Philosophy. Methods In order to achieve the purpose of this study, literature analysis related to J.pieper's concept of ‘leisure’ was conducted, and based on this, a new concept of work was defined agricultural education in practical arts. Results The meaning and value of work in the career education established through this study are as follows. First, work in career education is at the point where Ratio and Intellectus are united, and can be called'self understanding as a product of practical conduct. Second, work in career education is a ‘existence and negotiation process’ that gives meaning in the course of work and grows in the process of change and adaptation. Third, work in career education can be said to be the “ideal stimulus of cultivation of mind” pursuing arts as an encounter between sensuous drive and formal drive. Fourth, work in career education is not a means to achieve external results or usefulness, but can be said to be ‘the highest good as leisure’, where work itself is the goal. Conclusions To experience work in agricultural education is not simply to learn agricultural-related skills, but to discover the holistic self in the process of work and to give value as an education that pioneers the future through various work experiences.
A study on the effect of creativity of youth who participated in arts and culture program on creative leadership
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Shin Yeonghwan
Published: November 2022

Objectives The purpose of this study is to analyze the effect of creativity of adolescents participating in arts and culture programs on creative leadership. Methods In order to achieve the purpose of this study, a survey was conducted targeting 700 second and third year high school students located in Daejeon Metropolitan City, Gyeonggi-do, Gangwon-do, Gyeongsangbuk-do, and Chungcheong-do. Among the non-probability sampling methods, the objective sampling method was applied. Five sub-factors of creativity were selected as curiosity, sensitivity, task obsession, humor, and independent adventure, and three sub-factors of creative leadership were problem-solving leadership, personal leadership, and social leadership. Results Through this study, the positive influence relationship between creativity and creative leadership, that is, problem-solving leadership, personal leadership, and social leadership, was confirmed among adolescents who had participated in arts and cultural education programs. Since the sub-factors of creativity according to the characteristics of participants have been identified, the results of this study are expected to contribute to the development of specific creativity. In addition, it will be useful as a basic data for the development, dissemination and education of customized arts and culture programs according to the characteristics of school-age adolescents. Conclusions Since the influence of the creativity of the youth who participated in the arts and culture program on creative leadership has been confirmed, it is necessary to develop an effective arts and culture program to promote the creativity of the youth and to strengthen the creative leadership competency.
A Study on the Exploration the Experiences of Professors and Learners in the Class Applied to Innovative Teaching Method: Focused on the Case of Flipped Learning and Problem-Based Learning in University A
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Jang Yeon-Ju , Kim Eun-Young
Published: November 2022

Objectives This study attempted to derive a strategy to revitalize flipped learning and problem-based learning subjects applying innovative teaching methods in university education through a case study at A University located in Gwangju City. Methods To this end, in-depth interviews were conducted with 6 professors and 11 students selected as excellent teachers in 2019 and 2020 among the subjects applying the innovation teaching method at A University. Ant the results were analyzed through qualitative research. In addition, the reflection log in the professors’ class result report was also collected and analyzed together. Results As a result, 11 topics were derived from three aspects as follows. In terms of learning experience, the topics of interaction between professors and students, among students, a regret as a non-face-to-face classes, and classes with a lot of load for professors and students were derived, and in terms of learning performance, active classes, classes cultivating social skills and cooperation skills, and fulfilling classes were derived. Finally, in terms of support from center for the teaching and learning, the topics of system improvement, learning environment support, case and information sharing, and program development timing and form minimization were derived. Conclusions Through this study, it is hoped that university education innovation officials and instructors related to innovative teaching methods will be able to find meaningful implications for finding ways to implement high-quality educational innovation classes.
Comparison of Elementary School Teachers and Elementary Higher Grade Students' Perceptions on Excellent Classes in the Post-Corona Era
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Kwak Byeong Jun , Sohn Eun Kyong , Hwang Ji Hyeon , Kim Dae Kwon
Published: November 2022

Objectives The purpose of this study is to derive the characteristics of excellent classes through comparing the opinions of elementary school teachers and higher grade of a elementary school students on excellent classes. Methods n-depth interviews were conducted with teachers with experience in class research and professional development and students with excellent academic achievement and classes attitude, and network comparison analysis was conducted on the results. Based on the network comparison analysis conducted, the opinions of teachers and students were compared, and commonalities and differences were derived. Results As a result of the study, in opinions on excellent classes, teachers show efforts and methods to develop self-directed learning skills and literacy of students who have fallen to COVID-19, and students show methods and efforts to participate in classes and actively interact with teachers and other students. Studies on excellent class before COVID-19 and this study commonly said that interaction in class is important for both teachers and students in opinions on good classes. Conclusions In this study, the teacher emphasized more student-centered classes, saying that excellent class in the post-COVID-19 era are classes that develop self-directed learning skills of students who have fallen due to COVID-19. In addition, it was emphasized that students' literacy skills, which are lower than before due to online lectures, should also be improved.
Method of Reading Kim Kwang-gyun's Poems to Expand Philosophical Perception of Death
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Oh Jeong Hun
Published: November 2022

Objectives The purposes of this study were to attempt as such is expected to help readers break away from the narrow-mindedness of appreciating Kim Kwang-gyun’s poems from the fixed viewpoint of modernists while securing the usefulness to overcome the restriction of appreciation to compress death-related poetry works into themes such as the frustration and anxiety of humans due to the finiteness or death of humans. Methods For this purpose, Kim Gwang-gyun's works were analyzed in terms of death poetics. The discussion was conducted in relation to the literature study on existing philosophical discussions, and the emotions of others, communication with others, and the paradox of overcoming anxiety were examined in order to suggest a method of appreciation and education based on a qualitative study. Results The purposes of this study were to the poetic educational attitude as such will become a momentum to expand the audience-centered diverse appreciations and interpretations and is expected to enable students to acquire emotion-centeredness that departs from reason, others-orientedness instead of subject-centered thoughts, and the expansion of perception of the meaning of human existence through spiritual overcoming of death. Conclusions Students can reflectively reflect on their subject-centered customs by indirectly experiencing death, which cannot be experienced by the subject, through the death of others and immersing in others’ emotions in the process and furthermore, they can implement the possibility of others-centered communication. In addition, it is regarded that by identifying the cause of anxiety due to death and exploring the meaning of human existence through the foregoing, they can improve their attitude toward real life.
“Snooker” Ruvinsky: World Champ from the YMHA
Authors: Sahker Harvey
Published: November 2022

Irving “Snooker” Ruvinsky was a much-travelled catcher. A product of Montreal’s sandlots, Ruvinskyplayed semipro ball in England for a few years during the 1930s. While there, he donned the “tools of ignorance”for the first world amateur champions: England, in 1938.
When Toronto Was A Two-Team City: 1914 and the Effects of the Federal League
Authors: Dunkle Jonathan
Published: November 2022

In 1914, Toronto was one of the largest cities in North America. Already home to the Toronto MapleLeafs baseball club of the International League operated by James McCa!ery, Toronto became a target for theplacement of a major league team by the newly formed Federal League. #is article examines the attempts ofthe Federal League to establish a franchise in Toronto, as well as McCa!ery’s making Toronto a two-team townby relocating a Canadian League team to Toronto to serve as a farm club for his Maple Leafs.
Optimization Sentimen Analysis using CRISP-DM and Naive Bayes Methods Implemented on Social Media
Authors: Kurniawan Denni , Yasir Muhammad
Published: November 2022

Freedom of expression on social media Twitter not always give positive value, because sometimes can contains negative things such as fake news, spreads hate speech, and racism, where these kinds of tweet can be categorized as an act of Cyberbullying. Where this cyberbullying tends to increase every time. The aim of this study is to use the Naïve Bayes method in classifying types of sentiment on Twitter. The keyword used is Saipul Jamil, and the tweet was taken in September 2021. A total of 18,067 tweets were collected and then they will be labelled with a positive or negative value. This study also uses the CRIPS-DM method which is consist of Business Understanding, Data Understanding, Data Preparation, Modeling, Evaluation, and Deployment stages. The results of this study obtained the value of Accuracy (85.6%), Negative Recall (82.1%), Positive Recall (90.23%), and Negative Precision (91.76%) Positive Precision (79.18%).