bluuebunny/crossref_metadata_2025 huggingface dataset:
Exploring the inclusion of dental providers on interprofessional healthcare teams treating patients with chronic obstructive pulmonary disease: a rapid review
Authors: Novosel Navia I. , Fratarcangeli Greta J. , Randhawa Jasdip , Novosel Olivia M. , Sibbald Shannon L.
Published: November 2020

Chronic obstructive pulmonary disease (COPD) is the third leading cause of death in the world. Emerging concepts like One Health, integrated care models for COPD, and associations between oral and respiratory health are innovative ways to approach COPD treatment. This study explored contemporary evidence on the inclusion of dental providers on interprofessional healthcare teams treating patients with COPD. The first objective was to explore the current state of interprofessional care for COPD, and the second objective was to explore dentistry used in interprofessional care. A rapid review was conducted from January–June 2020 using Scopus and PubMed. Upon assessing for duplication and relevance, 85 articles were included for Objective 1, and 194 for Objective 2. The literature suggests that when dental providers are included on interprofessional healthcare teams, treatment outcomes for patients with multi-morbid, chronic disease such as COPD, are improved. The papers collected for review suggest that educational and clinical programs should implement interprofessional collaboration when treating chronic diseases. Healthcare teams can utilize the expertise of professionals outside the traditional medical field to better understand patients’ needs. Healthcare administration should consider a One Health approach when developing COPD treatment guidelines. We believe our results are transferable to the Canadian healthcare system. The collaborative nature and holistic philosophy of a One Health approach provides a novel way to develop policies and procedures that can effectively address the burden of COPD.
Analysis and study of the potential increase in energy output generated by prototype solar tracking, roof mounted solar panels
Authors: Harazin Jacek , Wróbel Andrzej
Published: November 2020

Roof mounted solar panels come in form of fixed panels, unable to adjust to sun’s position during day and throughout the year. As an effect, the efficiency of such solution is usually dependent on the roof slope and position of the building in relation to sun’s day arc during seasons. These problems can be bypassed in free standing solar installations by equipping solar panels with solar tracker installations. Thanks to solar tracking, solar panels can be dynamically positioned perpendicular to the sun position and gather energy more efficiently throughout the day. This article presents a possibility of creating a roof mounted solar tracking panel to increase its efficiency. A prototype of solar tracking panel with two axes of movement was designed with an intention of an easy adaptation to being mounted on sloped surfaces of building roofs. A reference stationary panel was used to compare the efficiency of both solutions. A 5-day study was carried out to determine if the proposed solution could provide any benefits. Based on the study, the authors made an attempt to draw a conclusion whether the design could considerably increase the solar energy output to be worth the extra spending associated with solar tracker installation.
What next after GDP-based cost-effectiveness thresholds?
Authors: Chi Y-Ling , Blecher Mark , Chalkidou Kalipso , Culyer Anthony , Claxton Karl , Edoka Ijeoma , Glassman Amanda , Kreif Noemi , Jones Iain , Mirelman Andrew J. , Nadjib Mardiati , Morton Alec , Norheim Ole Frithjof , Ochalek Jessica , Prinja Shankar , Ruiz Francis , Teerawattananon Yot , Vassall Anna , Winch Alexander
Published: November 2020

Public payers around the world are increasingly using cost-effectiveness thresholds (CETs) to assess the value-for-money of an intervention and make coverage decisions. However, there is still much confusion about the meaning and uses of the CET, how it should be calculated, and what constitutes an adequate evidence base for its formulation. One widely referenced and used threshold in the last decade has been the 1-3 GDP per capita, which is often attributed to the Commission on Macroeconomics and  WHO guidelines on Choosing Interventions that are Cost Effective (WHO-CHOICE). For many reasons, however, this threshold has been widely criticised; which has led experts across the world, including the WHO, to discourage its use. This has left a vacuum for policy-makers and technical staff at a time when countries are wanting to move towards Universal Health Coverage.

This article seeks to address this gap by offering five practical options for decision-makers in low- and middle-income countries that can be used instead of the 1-3 GDP rule, to combine existing evidence with fair decision-rules or develop locally relevant CETs. It builds on existing literature as well as an engagement with a group of experts and decision-makers working in low, middle and high income countries.
Big Five Personality Traits and Creativity
Authors: Jirásek Michal , Sudzina František
Published: November 2020

Purpose: Personality traits represent an important driver of creativity. Several studies linked individual personality traits and creativity, yet in most cases, the literature provides contradictory insights. In this study, we quasi-replicate prior studies using a new sample to assess the reliability of previous research. Furthermore, we explore the topic in greater detail, as we also study the relationship of creativity with personality facets, a more fine-grained alternative.Methodology/Approach: The study uses a survey-based sample of students from Denmark. To measure personality traits and facets, we asked respondents to fill 44 items Big Five Personality Inventory. We measured creativity using three items from the HEXACO-60 personality inventory. The data were analyzed using generalized least squares models with gender as a control.Findings: In line with the previous literature, our research showed that Openness to Experience is positively related to creativity. We found similar, yet statistically weaker evidence for the relationship of Extraversion and creativity. In contrast to most of the previous findings, we also reported a negative relationship between Conscientiousness and creativity.Research Limitation/Implication: Our research contributes to the topic of the relationship between personality traits and creativity. Some of the relationships fall into the area where the literature is not coherent. We propose that the explanation may stem from the too broad formulation of personality traits, and we partially show that using personality facets. For this reason, future research needs to go into detail of individual personality traits.Originality/Value of paper: The paper provides further insight into the relationship between personality and creativity.
Learning Needs Determination for Industry 4.0 Maturity Development in Automotive Organisations in Slovakia
Authors: Sütőová Andrea , Šooš Ľubomír , Kóča Ferdinand
Published: November 2020

Purpose: This paper aims to present the results of the study focused on the assessment of Industry 4.0 (I4.0) maturity level and adoption level of Quality 4.0 (Q4.0) intelligent technologies in organisations operating in the automotive industry in Slovakia (OEMs, Tier 1 and Tier 2 suppliers). The results serves as inputs for identification of learning and development needs.Methodology/Approach: The background of the study was a literature review and quantitative research. The I4.0 maturity model published by PwC (2016) was used in the study, while dimension elements were adjusted to the specifics of the automotive industry.Findings: Tier 1 and Tier 2 automotive suppliers are in the early stages of I4.0 maturity and adoption of Q4.0 intelligent technologies. OEMs achieve the level of horizontal collaborators in most of the dimensions. Q4.0 intelligent technologies are mostly adopted at an average level. Further development of OEMs to achieve the level of digital champions requires new disruptive business models and a fully integrated partner ecosystem.Research Limitation/Implication: The research is limited by the sample size and target levels of particular dimensions, related elements and Q4.0 intelligent technologies, which were not examined.Originality/Value of paper: The results bring more in-depth insight into the current state of I4.0 maturity and Q4.0 technology adoption level of the automotive organisations in Slovakia. There is no evidence of the study examining holistically the I4.0 maturity and Q4.0 technologies in the automotive.
EFECTO DE SCRATCH EN EL APRENDIZAJE DE CONCEPTOS GEOMÉTRICOS DE FUTUROS DOCENTES DE PRIMARIA
Authors: Martínez Zarzuelo Angélica , Rodríguez Mantilla Jesús Miguel , Roanes Lozano Eugenio , Fernández Díaz María José
Published: November 2020

El objetivo es evaluar el efecto de la Geometría de la Tortuga del lenguaje de programación Scratch 2 en el aprendizaje de conceptos geométricos de futuros profesores de Primaria. Se ha realizado un estudio cuasi-experimental en la Facultad de Educación de la Universidad Complutense de Madrid. Se han hecho análisis descriptivos, diferenciales y correlacionales sobre el rendimiento académico y la satisfacción de los estudiantes con una metodología con Scratch 2 y, además, análisis clúster para la identificación de tipologías de alumnado. Los resultados muestran que los estudiantes que han seguido esta metodología tienen niveles significativamente más altos en geometría. Se han identificado tres tipologías de alumnado, estando relacionado su rendimiento matemático y su actitud hacia la metodología. Así, esta metodología favorece el desarrollo de habilidades geométricas en futuros docentes de Primaria.
Barriers for the use of outdoor gyms in adults and elderly from a southern city of Brazil
Authors: Bergmann Gabriel Gustavo , Streb Anne Ribeiro , Ferrari Marcos , Alves Deivid Cristiano Cooper , Soares Bruna Adamar Castelhano , Ferreira Gustavo Dias , Pinheiro Eraldo dos Santos
Published: November 2020

The aim of this study was to identify barriers to use Outdoor Gyms (OGs) for physical activity (PA) practice and to examine their association with leisure-time PA, demographic and socioeconomic variables in adults and elderly. This cross-sectional population-based study enrolled 431 adults and elderly (66.8% women) aged 18 to 87 years living in the surroundings (up to 500 meters) of four OGs. Information about using OGs for PA practice, barriers to use OGs, leisure-time PA, demographic and socioeconomic variables were collected by domiciliary interview. Associations between barriers to use OGs with other included variables were analyzed using Chi-Square test. None barriers was reported for 29.2% (95%CI: 24.9-33.5) of the participants, being almost of then OGs’ users. The most reported barriers to use OGs were lack of time (21.6%; 95%CI: 17.7-25.5), lack of interest (16.5%; 95%CI: 13.0-20.0) and laziness (10.7%; 95%CI: 7.8-13.6). Intrapersonal barriers were more often among men, interpersonal among women and environmental among those with less educational level (p < 0.05). In conclusion, OGs’ users perceived fewer barriers than non-users, and most barriers to the use of OGs were intrapersonal with lack of time being the most prevalent.
Is the incorporation of primary care networks helpful?
Authors: Cumberlege Justin
Published: November 2020

Justin Cumberlege from specialist healthcare law firm Hempsons, provides some guidance on incorporating a primary care network
Treatment of acute idiopathic polyradiculoneuritis with intravenous human immunoglobulin therapy
Authors: Hooper Emily
Published: November 2020

The patient was presented to a veterinary hospital with acute progressive onset of non-ambulatory tetraparesis. An appropriate diagnosis of acute idiopathic polyradiculoneuritis was made and suitable supportive nursing care implemented. The patient was later diagnosed with pneumonia as a consequence of prolonged recumbency, requiring further nursing interventions. Treatment with intravenous human immunoglobulin therapy was subsequently initiated and the patient improved but was sadly later euthanased.
Venous thromboembolism in orthopaedic oncology
Authors: Lex Johnathan R. , Evans Scott , Cool Paul , Gregory Jonathan , Ashford Robert U. , Rankin Kenneth S. , Cosker Tom , Kumar Amit , Gerrand Craig , Stevenson Jonathan ,   On behalf of the British Orthopaedic Oncology Society VTE Committee
Published: November 2020

Aims

Malignancy and surgery are risk factors for venous thromboembolism (VTE). We undertook a systematic review of the literature concerning the prophylactic management of VTE in orthopaedic oncology patients.

Methods

MEDLINE (PubMed), EMBASE (Ovid), Cochrane, and CINAHL databases were searched focusing on VTE, deep vein thrombosis (DVT), pulmonary embolism (PE), bleeding, or wound complication rates.

Results

In all, 17 studies published from 1998 to 2018 met the inclusion criteria for the systematic review. The mean incidence of all VTE events in orthopaedic oncology patients was 10.7% (1.1% to 27.7%). The rate of PE was 2.4% (0.1% to 10.6%) while the rate of lethal PE was 0.6% (0.0% to 4.3%). The overall rate of DVT was 8.8% (1.1% to 22.3%) and the rate of symptomatic DVT was 2.9% (0.0% to 6.2%). From the studies that screened all patients prior to hospital discharge, the rate of asymptomatic DVT was 10.9% (2.0% to 20.2%). The most common risk factors identified for VTE were endoprosthetic replacements, hip and pelvic resections, presence of metastases, surgical procedures taking longer than three hours, and patients having chemotherapy. Mean incidence of VTE with and without chemical prophylaxis was 7.9% (1.1% to 21.8%) and 8.7% (2.0% to 23.4%; p = 0.11), respectively. No difference in the incidence of bleeding or wound complications between prophylaxis groups was reported.

Conclusion

Current evidence is limited to guide clinicians. It is our consensus opinion, based upon logic and deduction, that all patients be considered for both mechanical and chemical VTE prophylaxis, particularly in high-risk patients (pelvic or hip resections, prosthetic reconstruction, malignant diagnosis, presence of metastases, or surgical procedures longer than three hours). Additionally, the surgeon must determine, in each patient, if the risk of haemorrhage outweighs the risk of VTE. No individual pharmacological agent has been identified as being superior in the prevention of VTE events. Cite this article: Bone Joint J 2020;102-B(12)1743:–1751.
Treatment outcome of neonatal hip instability
Authors: Maikku Mari , Ohtonen Pasi , Valkama Marita , Leppilahti Juhana
Published: November 2020

Aims

We aimed to determine hip-related quality of life and clinical findings following treatment for neonatal hip instability (NHI) compared with age- and sex-matched controls. We hypothesized that NHI would predispose to hip discomfort in long-term follow-up.

Methods

We invited those born between 1995 and 2001 who were treated for NHI at our hospital to participate in this population-based study. We included those that had Von Rosen-like splinting treatment started before one month of age. A total of 96 patients treated for NHI (75.6 %) were enrolled. A further 94 age- and sex-matched controls were also recruited. The Copenhagen Hip and Groin Outcome Score (HAGOS) questionnaire was completed separately for both hips, and a physical examination was performed.

Results

The mean follow-up was 18.2 years (14.6 to 22.0). The HAGOS scores between groups were similar and met statistical and clinical significance only in the Symptoms subscale (mean difference 3.80, 95% confidence interval (CI) 0.31 to 7.29; p = 0.033). Those patients who had undergone treatment for NHI had a higher frequency of positive flexion-adduction-internal rotation test (odds ratio (OR) 2.6, 95% CI 1.2 to 5.6; p = 0.014), resisted straight leg rise test (OR 4.5, 95% CI 1.4 to 14.9; p = 0.014), and also experienced more pain in the groin during passive end range hip flexion (OR 2.5, 95% CI 1.2 to 5.3; p = 0.015) than controls.

Conclusion

NHI predisposes to hip discomfort in clinical tests, but no clinically relevant differences in experience of pain, physical function, and hip-related quality of life could be observed between the treated group and matched controls in 18 years of follow-up. Cite this article: Bone Joint J 2020;102-B(12):1767–1773.
Quality of patient-reported outcomes used for quality of life, physical function, and functional capacity in trials of childhood fractures
Authors: Marson Ben A. , Craxford Simon , Deshmukh Sandeep R. , Grindlay Douglas J. C. , Manning Joseph C. , Ollivere Benjamin J.
Published: November 2020

Aims

This study evaluates the quality of patient-reported outcome measures (PROMs) reported in childhood fracture trials and recommends outcome measures to assess and report physical function, functional capacity, and quality of life using the COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) standards.

Methods

A Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA)-compliant systematic review of OVID Medline, Embase, and Cochrane CENTRAL was performed to identify all PROMs reported in trials. A search of OVID Medline, Embase, and PsycINFO was performed to identify all PROMs with validation studies in childhood fractures. Development studies were identified through hand-searching. Data extraction was undertaken by two reviewers. Study quality and risk of bias was evaluated by COSMIN guidelines and recorded on standardized checklists.

Results

Searches yielded 13,672 studies, which were screened to identify 124 trials and two validation studies. Review of the 124 trials identified 16 reported PROMs, of which two had validation studies. The development papers were retrieved for all PROMs. The quality of the original development studies was adequate for Patient-Reported Outcomes Measurement Information System (PROMIS) Mobility and Upper Extremity and doubtful for the EuroQol Five Dimension Youth questionnaire (EQ-5D-Y). All other PROMs were found to have inadequate development studies. No content validity studies were identified. Reviewer-rated content validity was acceptable for six PROMs: Activity Scale for Kids (ASK), Childhood Health Assessment Questionnaire, PROMIS Upper Extremity, PROMIS Mobility, EQ-5D-Y, and Pediatric Quality of Life Inventory (PedsQL4.0). The Modified Disabilities of the Arm, Shoulder, and Hand (DASH) questionnaire was shown to have indeterminate reliability and convergence validity in one study and PROMIS Upper Extremity had insufficient convergence validity in one study.

Conclusion

There is insufficient evidence to recommend strongly the use of any single PROM to assess and report physical function or quality of life following childhood fractures. There is a need to conduct validation studies for PROMs. In the absence of these studies, we cautiously recommend the use of the PROMIS or ASK-P for physical function and the PedsQL4.0 or EQ-5D-Y for quality of life. Cite this article: Bone Joint J 2020;102-B(12):1599–1607.
Surgical treatment of the radial head is crucial for the outcome in terrible triad injuries of the elbow
Authors: Klug Alexander , Nagy Angela , Gramlich Yves , Hoffmann Reinhard
Published: November 2020

Aims

To evaluate the outcomes of terrible triad injuries (TTIs) in mid-term follow-up and determine whether surgical treatment of the radial head influences clinical and radiological outcomes.

Methods

Follow-up assessment of 88 patients with TTI (48 women, 40 men; mean age 57 years (18 to 82)) was performed after a mean of 4.5 years (2.0 to 9.4). The Mayo Elbow Performance Score (MEPS), Oxford Elbow Score (OES), and Disabilities of the Arm, Shoulder and Hand (DASH) score were evaluated. Radiographs of all patients were analyzed. Fracture types included 13 Mason type I, 16 type II, and 59 type III. Surgical treatment consisted of open reduction and internal fixation (ORIF) in all type II and reconstructable type III fractures, while radial head arthroplasty (RHA) was performed if reconstruction was not possible.

Results

At follow-up the mean MEPS was 87.1 (20 to 100); mean OES, 36.9 (6 to 48); and mean DASH score, 18.6 (0 to 90). Mean movement was 118° (30° to 150°) for extension to flexion and 162° (90° to 180°) for pronation to supination. The overall reoperation rate was 24%, with nine ORIF, ten RHA, and two patients without treatment to the radial head needing surgical revision. When treated with RHA, Mason type III fractures exhibited significantly inferior outcomes. Suboptimal results were also identified in patients with degenerative or heterotopic changes on their latest radiograph. In contrast, more favourable outcomes were detected in patients with successful radial head reconstruction after Mason type III fractures.

Conclusion

Using a standardized protocol, sufficient elbow stability and good outcomes can be achieved in most TTIs. Although some bias in treatment allocation, with more severe injuries assigned to RHA, cannot be completely omitted, treatment of radial head fractures may have an independent effect on outcome, as patients subjected to RHA showed significantly inferior results compared to those subjected to reconstruction, in terms of elbow function, incidence of arthrosis, and postoperative complications. As RHA showed no apparent advantage in Mason type III injuries between the two treatment groups, we recommend reconstruction, providing stable fixation can be achieved. Cite this article: Bone Joint J 2020;102-B(12):1620–1628.
Current actual success rate of the two-stage exchange arthroplasty strategy in chronic hip and knee periprosthetic joint infection
Authors: Corona Pablo S. , Vicente Matías , Carrera Lluís , Rodríguez-Pardo Dolors , Corró Sebastián
Published: November 2020

Aims

The success rates of two-stage revision arthroplasty for infection have evolved since their early description. The implementation of internationally accepted outcome criteria led to the readjustment of such rates. However, patients who do not undergo reimplantation are usually set aside from these calculations. The aim of this study was to investigate the outcomes of two-stage revision arthroplasty when considering those who do not undergo reimplantation, and to investigate the characteristics of this subgroup.

Methods

A retrospective cohort study was conducted. Patients with chronic hip or knee periprosthetic joint infection (PJI) treated with two-stage revision between January 2010 and October 2018, with a minimum follow-up of one year, were included. Variables including demography, morbidity, microbiology, and outcome were collected. The primary endpoint was the eradication of infection. Patients who did not undergo reimplantation were analyzed in order to characterize this subgroup better.

Results

A total of 162 chronic PJIs were included in the study. After a mean follow-up of 57.3 months (12.1 to 115.7), 18 patients (11.1%) did not undergo reimplantation, due either to medical issues (10), the patient’s choice (4), or death (4). When only considering those who underwent reimplantation, the success rate was 80.6%. However, when those who did not undergo reimplantation were included, the success rate dropped to 71.6%. Advanced age, American Society of Anesthesiologists grade ≥ III, McPherson’s C host, and Gram-negative related PJI were independent risk factors for retention of the spacer. The mortality was higher in the non-reimplanted group.

Conclusion

The real success rate of two-stage revision may not be as high as previously reported. The exclusion of patients who do not undergo reimplantation resulted in a 9% overestimation of the success rate in this series. Many comorbidity-related risk factors for retention of the spacer were identified, as well as higher death rates in this group. Efforts should be made to optimize these patients medically in order to increase reimplantation and success rates, while decreasing mortality. Cite this article: Bone Joint J 2020;102-B(12):1682–1688.
Analysis and identification of infrared radiation characteristics of different attitude targets
Authors: Gu Mu , Ren Qifeng , Zhou Jinmei , Liao Sheng
Published: November 2020

Today, a large number of targets operate in space, and there are mainly four kinds of attitude targets: triaxial stabilized targets, spin stabilized targets, triaxial stabilized targets on tumbling, and spin stabilized targets on tumbling. It is of great significance to classify and identify these targets. First, the infrared radiation characteristic model of the target is established, taking different attitude targets into account, which, to the best of our knowledge, has seldom been considered. Then, through the simulation of specific example targets, the differences in infrared characteristics of four kinds of attitude targets are analyzed and explained. Finally, according to the orbit distribution and typical geometry structure of space targets, the infrared characteristic data sets of four kinds of attitude targets are simulated, and a classifier is established to classify and recognize these targets. The results show that the infrared characteristics of different attitude targets are obviously different, and the classifier can successfully classify and recognize different attitude targets.
Visualization of volumetric defects and dynamic processes in crystals by digital IR-holography
Authors: Dyomin V. V. , Gribenyukov A. I. , Davydova A. Y. , Olshukov A. S. , Polovtsev I. G. , Podzyvalov S. N. , Yudin N. N. , Zinovev M. M.
Published: November 2020

The observation and study of defects of single-crystal multicomponent optical material is necessary to determine the qualitative characteristics and optical properties of a material and to diagnose its manufacturing procedures. This paper utilizes the digital IR-holography to measure the geometrical parameters, shape, and location of defects as well as to characterize them. The paper illustrates the examples of physical, chemical, and optical inhomogeneities. Also, the paper presents the results of the study of dynamic processes in optical elements under the influence of laser radiation with high power density. The possibility of using the digital holographic technology to determine the dynamics of optical breakdown in the

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single crystal is illustrated, namely, to estimate the speed and time of breakdown development, which can be used to interpret the mechanisms of breakdown development.
Pump and thermal impact on heavily erbium-doped fiber laser generation
Authors: Smirnov A. M. , Butov O. V.
Published: November 2020

A detailed comparative study of heavily erbium-doped fiber laser generation features was carried out in the case of 1490 nm and 976 nm wavelength pumping. The laser cavity was designed using point-by-point fiber Bragg grating inscription technology with femtosecond laser pulses. The CW and

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-switched lasing regimes were achieved depending on temperature and heat sink performance. It was found experimentally for the first time, to the best of our knowledge, that the frequency and pulse duration of

Q

-switched laser operations are primarily determined by the output laser power and do not depend on the pump wavelength. The pulse formation is caused by the lasing process itself and depends on the up-conversion rate at the generation wavelength. Additionally, the level of laser cavity heating at the

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-switched generation regime was defined.
Development of a sensitive molecular diagnostic assay for detecting Borrelia burgdorferi DNA from the blood of Lyme disease patients by digital PCR
Authors: Das Srirupa , Hammond-McKibben Denise , Guralski Donna , Lobo Sandra , Fiedler Paul N.
Published: November 2020

Lyme disease patients would greatly benefit from a timely, sensitive, and specific molecular diagnostic test that can detect the causal agent Borrelia burgdorferi at the onset of symptoms. Currently available diagnostic methods recommended by the Centers for Disease Control and Prevention for Lyme disease involve indirect serological tests that rely on the detection of a host-antibody response, which often takes more than three weeks to develop. With this process, many positive cases are not detected within a timely manner, preventing a complete cure. In this study, we have developed a digital polymerase chain reaction (PCR) assay that detects Lyme disease on clinical presentation with a sensitivity two-fold higher than that of the currently available diagnostic methods, using a cohort of patient samples collected from the Lyme disease endemic state of Connecticut, USA, in 2016–2018. Digital PCR technology was chosen as it is more advanced and sensitive than other PCR techniques in detecting rare targets. The analytical detection sensitivity of this diagnostic assay is approximately three genome copies of B. burgdorferi. The paucity of spirochetes in the bloodstream of Lyme disease patients has hindered the clinical adoption of PCR-based diagnostic tests. However, this drawback was overcome by using a comparatively larger sample volume, applying pre-analytical processing to the blood samples, and implementing a pre-amplification step to enrich for B. burgdorferi-specific gene targets before the patient samples are analyzed via digital PCR technology. Pre-analytical processing of blood samples from acute patients revealed that the best sample type for Lyme disease detection is platelet-rich plasma rather than whole blood. If detected in a timely manner, Lyme disease can be completely cured, thus limiting antibiotic overuse and associated morbidities.
A model of workflow in the hospital during a pandemic to assist management
Authors: Garbey Marc , Joerger Guillaume , Furr Shannon , Fikfak Vid
Published: November 2020

We present a computational model of workflow in the hospital during a pandemic. The objective is to assist management in anticipating the load of each care unit, such as the ICU, or ordering supplies, such as personal protective equipment, but also to retrieve key parameters that measure the performance of the health system facing a new crisis. The model was fitted with good accuracy to France’s data set that gives information on hospitalized patients and is provided online by the French government. The goal of this work is both practical in offering hospital management a tool to deal with the present crisis of COVID-19 and offering a conceptual illustration of the benefit of computational science during a pandemic.
Research on spatial characteristics of metropolis development using nighttime light data: NTL based spatial characteristics of Beijing
Authors: Yang Yuli , Ma Mingguo , Zhu Xiaobo , Ge Wei
Published: November 2020

As the capital and one of the metropolises in China, Beijing has met with a number of serious so-called "urban diseases" in the process of rapid urbanization such as blind expansion of urban areas, explosion of population and the increase of urban heat island effect. To treat these “urban diseases” and make the metropolis develop healthful and sustainable in Beijing in the future, the spatial characteristics of metropolis developments in Beijing are explored in this paper. The urban built-up areas in Beijing are extracted using the DMSP-OLS nighttime light data from 1992 to 2013. The characteristics of the urban developments of Beijing are studied, including spatial and temporal scales of urban developments, urban barycenter of Beijing and its transfer trajectory, variations of urban spatial forms and the differences of urban internal developments. The results have shown that the built-up areas had been increasing and circling extending from the central urban areas to the outer spaces in the last 21 years. The built-up area had expanded by 878km2 in 1992–2013, and the built-up area in 2013 had expanded to three times comparing to that of 1992. The expanding area of the built-up area in the northeast is the largest. The expansion of the urban had mainly occurred in 1996–2007, and the expanded area had accounted for 92% of the total research period. During the whole research period, the urban barycenter of Beijing had moved 5000.71 meters towards Northeast 28° of its original place from Dongcheng District to Chaoyang District. The development level of each municipal district had been increasing year by year, and the development differences among the municipal districts had been gradually reduced; the spatial forms of Beijing had been alternately changed between extensive and intensive expansion. The results of this study can help to plan urban land use and people migration of Beijing.
Forecasting COVID-19 in Pakistan
Authors: Ali Muhammad , Khan Dost Muhammad , Aamir Muhammad , Khalil Umair , Khan Zardad
Published: November 2020

Objectives

Forecasting epidemics like COVID-19 is of crucial importance, it will not only help the governments but also, the medical practitioners to know the future trajectory of the spread, which might help them with the best possible treatments, precautionary measures and protections. In this study, the popular autoregressive integrated moving average (ARIMA) will be used to forecast the cumulative number of confirmed, recovered cases, and the number of deaths in Pakistan from COVID-19 spanning June 25, 2020 to July 04, 2020 (10 days ahead forecast).

Methods

To meet the desire objectives, data for this study have been taken from the Ministry of National Health Service of Pakistan’s website from February 27, 2020 to June 24, 2020. Two different ARIMA models will be used to obtain the next 10 days ahead point and 95% interval forecast of the cumulative confirmed cases, recovered cases, and deaths. Statistical software, RStudio, with “forecast”, “ggplot2”, “tseries”, and “seasonal” packages have been used for data analysis.

Results

The forecasted cumulative confirmed cases, recovered, and the number of deaths up to July 04, 2020 are 231239 with a 95% prediction interval of (219648, 242832), 111616 with a prediction interval of (101063, 122168), and 5043 with a 95% prediction interval of (4791, 5295) respectively. Statistical measures i.e. root mean square error (RMSE) and mean absolute error (MAE) are used for model accuracy. It is evident from the analysis results that the ARIMA and seasonal ARIMA model is better than the other time series models in terms of forecasting accuracy and hence recommended to be used for forecasting epidemics like COVID-19.

Conclusion

It is concluded from this study that the forecasting accuracy of ARIMA models in terms of RMSE, and MAE are better than the other time series models, and therefore could be considered a good forecasting tool in forecasting the spread, recoveries, and deaths from the current outbreak of COVID-19. Besides, this study can also help the decision-makers in developing short-term strategies with regards to the current number of disease occurrences until an appropriate medication is developed.
Spissistilus festinus (Hemiptera: Membracidae) susceptibility to six generalist predators
Authors: Kron Cindy R. , Sisterson Mark S.
Published: November 2020

Spissistilus festinus (Say) (Hemiptera: Membracidae) was shown to transmit Grapevine red blotch virus (GRBV) in a greenhouse study. Grapevines infected with GRBV exhibit reduced sugar accumulation, altered secondary metabolite production and delayed berry maturation that negatively impacts wine quality and economics. Augmentative biocontrol may be a useful integrated pest management (IPM) tool for suppressing S. festinus populations in vineyards, but minimal research has been conducted on testing potential predators against the different life stages of S. festinus. The susceptibility of S. festinus adults and nymphs (1st through 5th instar) to predation by six commercially available biocontrol agents in petri dish and bell bean plant arenas was determined under greenhouse conditions. No significant mortality of S. festinus nymphs or adults occurred when exposed to Cryptolaemus montrouzieri adults, C. montrouzieri larvae and Sympherobius barberi adults in petri dish or bell bean plant arenas. Significant mortality of 1st and 2nd instar nymphs of S. festinus in the presence of Zelus renardii nymphs was observed in petri dish but not in bell bean arenas. Hippodamia convergens adults and Chrysoperla rufilabris larvae both consumed a significant number of S. festinus nymphs in petri dish and bell bean arenas. No significant predation of S. festinus adults was documented in this experiment. Results of this study aid in identifying predators that may be suitable candidates for additional field testing to determine their potential efficacy as biocontrol agents of S. festinus in a vineyard setting.
The role of structured reporting and structured operation planning in functional endoscopic sinus surgery
Authors: Ernst Benjamin Philipp , Reissig Manuel René , Strieth Sebastian , Eckrich Jonas , Hagemann Jan H. , Döge Julia , Matthias Christoph , Gouveris Haralampos , Rübenthaler Johannes , Weiss Roxanne , Sommer Wieland H. , Nörenberg Dominik , Huber Thomas , Gonser Phillipp , Becker Sven , Froelich Matthias F.
Published: November 2020

Computed tomography (CT) scans represent the gold standard in the planning of functional endoscopic sinus surgeries (FESS). Yet, radiologists and otolaryngologists have different perspectives on these scans. In general, residents often struggle with aspects involved in both reporting and operation planning. The aim of this study was to compare the completeness of structured reports (SR) of preoperative CT images and structured operation planning (SOP) to conventional reports (CR) and conventional operation planning (COP) to potentially improve future treatment decisions on an individual level. In total, 30 preoperative CT scans obtained for surgical planning of patients scheduled for FESS were evaluated using SR and CR by radiology residents. Subsequently, otolaryngology residents performed a COP using free texts and a SOP using a specific template. All radiology reports and operation plannings were evaluated by two experienced FESS surgeons regarding their completeness for surgical planning. User satisfaction of otolaryngology residents was assessed by using visual analogue scales. Overall radiology report completeness was significantly higher using SRs regarding surgically important structures compared to CRs (84.4 vs. 22.0%, p<0.001). SOPs produced significantly higher completeness ratings (97% vs. 39.4%, p<0.001) regarding pathologies and anatomical variances. Moreover, time efficiency was not significantly impaired by implementation of SR (148 s vs. 160 s, p = 0.61) and user satisfaction was significantly higher for SOP (VAS 8.1 vs. 4.1, p<0.001). Implementation of SR and SOP results in a significantly increased completeness of radiology reports and operation planning for FESS. Consequently, the combination of both facilitates surgical planning and may decrease potential risks during FESS.
The risk of stroke/systemic embolism and major bleeding in Asian patients with non-valvular atrial fibrillation treated with non-vitamin K oral anticoagulants compared to warfarin: Results from a real-world data analysis
Authors: Bang Oh Young , On Young Keun , Lee Myung-Yong , Jang Sung-Won , Han Seongwook , Han Sola , Won Mi-Mi , Park Yoo-Jung , Lee Ji-Min , Choi Hee-Youn , Kang Seongsik , Suh Hae Sun , Kim Young-Hoon
Published: November 2020

Background

Although randomized trials provide a high level of evidence regarding the efficacy of non-vitamin K oral anticoagulants (NOACs), the results of such trials may differ from those observed in day-to-day clinical practice.

Aims

To compare the risk of stroke/systemic embolism (S/SE) and major bleeding (MB) between NOAC and warfarin in clinical practice.

Methods

Patients with non-valvular atrial fibrillation (NVAF) who started warfarin/NOACs between January 2015 and November 2016 were retrospectively identified from Korea’s nationwide health insurance claims database. Using inpatient diagnosis and imaging records, the Cox models with inverse probability of treatment weighting using propensity scores were used to estimate hazard ratios (HRs) for NOACs relative to warfarin.

Results

Of the 48,389 patients, 10,548, 11,414, 17,779 and 8,648 were administered apixaban, dabigatran, rivaroxaban and warfarin, respectively. Many patients had suffered prior strokes (36.7%, 37.7%, 31.4%, and 32.2% in apixaban, dabigatran, rivaroxaban, and warfarin group, respectively), exhibited high CHA2DS2-VASc (4.8, 4.6, 4.6, and 4.1 in apixaban, dabigatran, rivaroxaban, and warfarin group, respectively) and HAS-BLED (3.7, 3.6, 3.6, and 3.3 in apixaban, dabigatran, rivaroxaban, and warfarin group, respectively) scores, had received antiplatelet therapy (75.4%, 75.7%, 76.8%, and 70.1% in apixaban, dabigatran, rivaroxaban, and warfarin group, respectively), or were administered reduced doses of NOACs (49.8%, 52.9%, and 42.8% in apixaban, dabigatran, and rivaroxaban group, respectively). Apixaban, dabigatran and rivaroxaban showed a significantly lower S/SE risk [HR, 95% confidence intervals (CI): 0.62, 0.54–0.71; 0.60, 0.53–0.69; and 0.71, 0.56–0.88, respectively] than warfarin. Apixaban and dabigatran (HR, 95% CI: 0.58, 0.51–0.66 and 0.75, 0.60–0.95, respectively), but not rivaroxaban (HR, 95% CI: 0.84, 0.69–1.04), showed a significantly lower MB risk than warfarin.

Conclusions

Among Asian patients who were associated with higher bleeding risk, low adherence, and receiving reduced NOAC dose than that provided in randomised controlled trials, all NOACs were associated with a significantly lower S/SE risk and apixaban and dabigatran with a significantly lower MB risk than warfarin.
Automation, workers’ skills and job satisfaction
Authors: Schwabe Henrik , Castellacci Fulvio
Published: November 2020

When industrial robots are adopted by firms in a local labor market, some workers are displaced and become unemployed. Other workers that are not directly affected by automation may however fear that these new technologies might replace their working tasks in the future. This fear of a possible future replacement is important because it negatively affects workers’ job satisfaction at present. This paper studies the extent to which automation affects workers’ job satisfaction, and whether this effect differs for high- versus low-skilled workers. The empirical analysis uses microdata for several thousand workers in Norway from the Working Life Barometer survey for the period 2016–2019, combined with information on the introduction of industrial robots in Norway from the International Federation of Robotics. Our identification strategy exploits variation in the pace of introduction of industrial robots in Norwegian regions and industries since 2007 to instrument workers’ fear of replacement. The results indicate that automation in industrial firms in recent years have induced 40% of the workers that are currently in employment to fear that their work might be replaced by a smart machine in the future. Such fear of future replacement does negatively affect workers’ job satisfaction at present. This negative effect is driven by low-skilled workers, which are those carrying out routine-based tasks, and who are therefore more exposed to the risks of automation.
La música Jazz en la Institución Educativa: un viaje de traslación de la periferia al corazón del canon de la música culta en occidente
Authors: Merchán Sánchez-Jara Javier , Navarro Cáceres María
Published: November 2020

El presente artículo pretende constituirse como una aproximación teórica en torno al proceso de inserción y traslación de la música de jazz en el canon de la música culta en Occidente, monopolizado de manera paradigmática por la música clásica europea. Partiendo de un sustrato teórico conformado en relación a la teoría de los polisistemas, postulada por el investigador Israelí Itamar Even-Zohar, se analizan las sinergias, coyunturas y condicionantes que subyacen a un movimiento de traslación que ha propiciado el cambio de consideración de un género musical como el jazz, desde una concepción como música marginal y minoritaria, asociada a un contexto sociocultural concreto, hasta su reconocimiento como una de las expresiones artísticas más vanguardistas, refinadas y valoradas de la cultura occidental.
A zöldbeszerzés motivációs háttere (The motivational background of green purchasing)
Authors: Vörösmarty Gyöngyi
Published: November 2020

A vállalatok zöldbeszerzési gyakorlatának különbözőségei számos kutatást indukáltak. Ezek a kutatások egyrészt motivációs, illetve gátló tényezők keresésével, másrészt racionális szakmai kritériumokkal magyarázzák a vállalati beszerzési gyakorlat eltéréseit. Ez a tanulmány a nemzetközi szakirodalmi háttér áttekintése után egy kérdőíves felmérés segítségével elemzi a zöldbeszerzési gyakorlat egyes tevékenységeit azzal a céllal, hogy a motivációs tényezők beszerzési tevékenységekre gyakorolt hatását mutassa. Eredménye, hogy kapcsolatot azonosít a válaszadó személyes motiváltsága és a vállalatának beszállítók kezelésére vonatkozó gyakorlata között. ____ Green purchasing practice of companies has indicated a number of research publications. These publications investigate drivers and barriers but rarely focus on how these motivational factors influence supplier management practice. The aim of this paper is to investigate this relationship. After presenting some literature results on motivation and identification of elements of green supplier management practice it will describe the research framework highlighting personal motivational attitudes. Survey results will be presented.
A felelős vállalatirányítás személyi tényezői: A CSR-központ felelős vállalatvezetők attitűdjének vizsgálata a kis- és középvállalatok körében
Authors: Benedek Andrea , Takácsné György Katalin
Published: November 2020

A vállalatok társadalmi felelősségvállalása és a felelős vállalatirányítás meghatározó tényező a hosszú távú vállalati stratégia megalapozása, a versenyképesség és a fogyasztói lojalitás megőrzése szempontjából. Az elmúlt időszakban kissé megfakult bizalmi környezetben (foglalkoztatáspolitikai, élelmiszer és egyéb botrányok, pénzpiaci dereguláció stb.) különösen meghatározó kérdéssé vált a CSR, melynek eszközrendszere számos lehetőséget biztosít a döntéshozók számára, hogy valamennyi érintett elégedett legyen. Ám a vállalatirányítás marsallbotja a vezető kezében van. A CSR-központú vállalatirányítás meghatározó eleme maga a vezető, s annak elkötelezettsége, habitusa, etikai tartása, hajlama, szocializációs tapasztalata. A kutatás egy olyan vizsgálati eredményt mutat be, mely a kis- és középvállalatok vezetőinek CSR-központú irányítási szemléletét, beállítódását vizsgálja. A vezetők, CSR-attitűdjüket tekintve, három, egymástól jól elhatárolható vállalatvezetői csoportba sorolhatók: a hagyományos, semleges és modern CSR-nézetet valló vállalatvezetői klaszterekbe. A vizsgálat során meghatározott vezetői szegmensek jól pozicionálható, jól célozható csoportokat képeznek, mely a jövő felelős vállalatirányításának szempontjából biztató, mert a kis- és középvállalkozók többsége, CSR-attitűdjüket tekintve már túllépett a kizárólag tulajdonosi érdeket szem előtt tartó, hagyományos nézeten.
Nexus efficiency of centralized and decentralized models for water management and food production in the region of Alentejo , Portugal
Authors: Guarín Cifuentes Diego Alexander
Published: November 2020

To stress the importance of sustainable water management through decentralized models such as water retention landscapeas a feasible alternative for regional self sufficiency and regenerative basis for autonomous water supply and food production