bluuebunny/crossref_metadata_2025 huggingface dataset:
The effects of resistance training on denervated myofibers, senescent cells, and associated protein markers in middle‐aged adults
Authors: Ruple Bradley A. , Mattingly Madison L. , Godwin Joshua S. , McIntosh Mason C. , Kontos Nicholas J. , Agyin‐Birikorang Anthony , Michel J. Max , Plotkin Daniel L. , Chen Shao‐Yung , Ziegenfuss Tim N. , Fruge Andrew D. , Gladden L. Bruce , Robinson Austin T. , Mobley C. Brooks , Mackey Abigail L. , Roberts Michael D.
Published: April 2024

Denervated myofibers and senescent cells are hallmarks of skeletal muscle aging. However, sparse research has examined how resistance training affects these outcomes. We investigated the effects of unilateral leg extensor resistance training (2 days/week for 8 weeks) on denervated myofibers, senescent cells, and associated protein markers in apparently healthy middle‐aged participants (MA, 55 ± 8 years old, 17 females, 9 males). We obtained dual‐leg vastus lateralis (VL) muscle cross‐sectional area (mCSA), VL biopsies, and strength assessments before and after training. Fiber cross‐sectional area (fCSA), satellite cells (Pax7+), denervated myofibers (NCAM+), senescent cells (p16+ or p21+), proteins associated with denervation and senescence, and senescence‐associated secretory phenotype (SASP) proteins were analyzed from biopsy specimens. Leg extensor peak torque increased after training (p < .001), while VL mCSA trended upward (interaction p = .082). No significant changes were observed for Type I/II fCSAs, NCAM+ myofibers, or senescent (p16+ or p21+) cells, albeit satellite cells increased after training (p = .037). While >90% satellite cells were not p16+ or p21+, most p16+ and p21+ cells were Pax7+ (>90% on average). Training altered 13 out of 46 proteins related to muscle–nerve communication (all upregulated, p < .05) and 10 out of 19 proteins related to cellular senescence (9 upregulated, p < .05). Only 1 out of 17 SASP protein increased with training (IGFBP‐3, p = .031). In conclusion, resistance training upregulates proteins associated with muscle–nerve communication in MA participants but does not alter NCAM+ myofibers. Moreover, while training increased senescence‐related proteins, this coincided with an increase in satellite cells but not alterations in senescent cell content or SASP proteins. These latter findings suggest shorter term resistance training is an unlikely inducer of cellular senescence in apparently healthy middle‐aged participants. However, similar study designs are needed in older and diseased populations before definitive conclusions can be drawn.
A Comparison of 2 Cage Sizes in Biportal Endoscopic Transforaminal Lumbar Interbody Fusion
Authors: Kim Ju-Eun , Kim Hyunwoo , Park Eugene J. , Park Daniel K.
Published: April 2024

Study Design:

Retrospective study.

Objective:

This study compared the fusion and subsidence rate and clinical outcomes when using different-sized static PEEK cages in BE-TLIF.

Summary of Background Data:

Biportal endoscopic techniques for transforaminal lumbar interbody fusion (BE-TLIF) have been shown to have similar clinical and fusion outcomes with faster clinical recovery in comparison to tubular surgery. Subsidence of the interbody, however, could be a complication.

Methods:

Patients who underwent 1 or 2 level BE-TLIF for degenerative and isthmic spondylolisthesis between January 2019 and January 2022 were included. A 32×10 mm cage (group A) and a 40×15 mm cage (group B) were compared. The visual analog scale (VAS) for back and leg symptoms, and Oswestry disability index (ODI) were collected. Plain radiographs and computed tomography assessed fusion and subsidence at a minimum of 12 months.

Results:

Of the 69 enrolled patients, 39 group A patients (51 levels) and 30 group B patients (32 levels) were compared. The operation time per level was 123 ± 15.8 and 138 ± 10.5 minutes per fusion level in groups A and B, respectively (P < 0.05). ODI improved from 64.8 ± 6.2 to 15.7 ± 7.1 in group A and from 65.3 ± 5.6 to 15.1 ± 6.3 in group B at the final follow-up (P < 0.05). VAS leg and back score improvement between the groups did not differ; however, the 3-month postoperative VAS back improvement was significantly higher in group B. The final fusion rate at the final follow-up did not significantly differ; however, the fusion ratio at 1 year was higher in group B (P < 0.05). Subsidence occurred in 5 cases (9.8%) in group A and none in group B (P < 0.05).

Conclusion:

BE-TLIF using a larger cage can be performed safely with similar patient-reported outcome measures with a faster fusion rate with less subsidence risk.

Level of Study:

III
Prior cocaine self-administration does not impair the ability to delay gratification in rats during diminishing returns
Authors: Pribut H.J. , Kang N. , Roesch Matthew R.
Published: April 2024

Previous exposure to drugs of abuse produces impairments in studies of reversal learning, delay discounting and response inhibition tasks. While these studies contribute to the understanding of normal decision-making and how it is impaired by drugs of abuse, they do not fully capture how decision-making impacts the ability to delay gratification for greater long-term benefit. To address this issue, we used a diminishing returns task to study decision-making in rats that had previously self-administered cocaine. This task was designed to test the ability of the rat to choose to delay gratification in the short-term to obtain more reward over the course of the entire behavioral session. Rats were presented with two choices. One choice had a fixed amount of time delay needed to obtain reward [i.e. fixed delay (FD)], while the other choice had a progressive delay (PD) that started at 0 s and progressively increased by 1 s each time the PD option was selected. During the ‘reset’ variation of the task, rats could choose the FD option to reset the time delay associated with the PD option. Consistent with previous results, we found that prior cocaine exposure reduced rats’ overall preference for the PD option in post-task reversal testing during ‘no-reset’ sessions, suggesting that cocaine exposure made rats more sensitive to the increasing delay of the PD option. Surprisingly, however, we found that rats that had self-administered cocaine 1-month prior, adapted behavior during ‘reset’ sessions by delaying gratification to obtain more reward in the long run similar to control rats.
Genetic aortopathies: a case-based approach to multidisciplinary program development
Authors: Jordan Christopher P. , Berthold Akos , Bonomo Jason
Published: April 2024

Purpose of review

The incorporation of genetic counseling and testing is essential to evaluation and management of thoracic aortic disease in patients under 60 years of age and those with family histories suspicious for heritable thoracic aortic disease and disorders associated with increased risk for acute type-A aortic dissection.

Recent findings

As many as 20% of individuals with thoracic aortic disease under the age of 60 years have autosomal dominant patterns of inheritance. A considerable number of heritability factors remain undefined for these families.

Genetic aortopathy programs require a collaborative approach including cardiovascular specialists and surgeons, medical geneticists, genetic counselors, and allied healthcare professionals. Comprehensive evaluation and management of these patients includes collection of detailed phenotypic data to inform the broader community and identify new associated and causative genes of interest, genetic modifiers, and other risk factors. These programs optimize outcomes and reduce the overall burden in the population of acute aortic dissection and related comorbidities.
Effect of Corneal and Lens Eccentricity Difference on Rigid Corneal Lens Treatment in Patients With Keratoconus
Authors: Kwon Younga , Han Sang Beom , Che Song-A , Koh Kyungmin , Han So Young , Choi Chul Young , Lee Yong Woo
Published: April 2024

Objective:

To evaluate the effects of rigid corneal lenses (RCL) in patients with keratoconus, based on eccentricity.

Methods:

Eighty-four eyes from 84 patients were included in this retrospective comparative study. Based on the median value of eccentricity difference between the cornea and back surface of the RCL, the patients were divided into groups 1 (<0.08) and 2 (≥0.08). Visual acuity, refractive index, and corneal topography indices were compared before and three months after lens use.

Results:

Visual acuity, astigmatism, refractive error, corneal curvature, and corneal thickness improved significantly in both groups. Apical power and anterior elevation improved significantly in group 1, with small differences in eccentricity, but not in group 2. Changes in apical power before and after lens use were significantly different between the two groups.

Conclusion:

The RCL was effective for the cornea of keratoconus, especially when the prescription was made with a small difference in eccentricity.
Outcomes of Referrals in Pediatric Patients With Peripheral Lymphadenopathy
Authors: Six Kathryn A. , Aban Inmaculada B. , Daniels Gabriel M. , Wolfson Julie , Beierle Elizabeth A. , Kutny Matthew A. , Lebensburger Jeffrey , Xavier Ana C.
Published: April 2024

Lymphadenopathy is a common reason for referral to a subspecialist, which may result in significant anxiety for parents. Understanding which patients require a subspecialty referral for lymphadenopathy is key to streamlining health care utilization for this common clinical entity. This is an IRB-approved retrospective study examining pediatric patients consecutively referred to pediatric hematology oncology, otolaryngology, or surgery for lymphadenopathy from 2012 to 2021 at a free-standing tertiary-care children’s hospital. Logistic regression was fitted to examine the association between the maximum size of the lymph nodes (LN) and a diagnosis of malignancy. The odds ratio, area under the receiver operator curve, sensitivity, and specificity were estimated. We found a significant association between LN size and cancer diagnosis. For every centimeter increase in the maximal dimension of LN, there was an estimated 2.3 times increase in the odds of malignancy (OR=2.3, 95% CI: 1.65-3.11; P<0.0001). The estimated area under the curve (0.84, 95% CI: 0.78-0.90) indicated that LN size correlated well with cancer diagnosis. A LN cut-off size of 2 cm resulted in an estimated sensitivity of 1.0 (95% CI: 0.87-1.00) and specificity of 0.54 (95% CI: 0.46-0.61). Maximum LN size may be a predictor of malignancy among pediatric patients with lymphadenopathy.
Balamuthia Amebic Encephalitis Cured and Discharged
Authors: Qin Benda , Jia Liyan , Chen Jian , Liu Wei
Published: April 2024

Intracerebral granulomatous infectious encephalitis caused by Baboon Balamuthia amoeba is a rare form of infectious granulomatous amoebic encephalitis. There are very limited case reports of cured discharges. The authors report a 59-year-old male patient who met the diagnostic criteria for granulomatous infection caused by Baboon Balamuthia amoeba. After treatment, the patient’s condition improved, and he was discharged from the hospital. The authors reviewed the data of this patient, analyzed relevant imaging information, and summarized our experience to enhance understanding of this condition.
Pilot evaluation of a digital approach to occupational therapy home assessments: acceptability and efficiency compared with usual practice in a hospital
Authors: Spalding Kaitlyn , Watson Kylie , Tornatore Giovanna , Laracy Sue , Doig Emmah
Published: April 2024

Introduction:

Pre-discharge home assessments by occupational therapists facilitate safe and timely discharge from hospital and are associated with better health outcomes. Digital technology offers the potential to reduce duplication of documentation and improve communication and sharing of home assessment findings.

Objective:

This quality improvement project evaluated time-cost; clinician satisfaction and confidence; and acceptability of the use of a digital approach to home assessments.

Methods:

A prospective, cross-sectional design was used to compare usual practice with the digital approach across two sub-acute wards in a large metropolitan hospital in Queensland, Australia. Time to document and conduct home assessments as well as clinician satisfaction and confidence were compared using descriptive statistics. Clinician perspectives about the home assessment approaches were collected through a survey and analyzed using content analysis.

Results:

Home assessment and documentation time were significantly lower for the home assessments conducted using the digital approach compared with usual practice assessments. Clinician satisfaction with using digital technology was higher.

Conclusions:

The introduction of this simple technology reduced clinicians’ time to conduct home assessments and document home assessment reports. The project was well received by occupational therapy clinicians.

Spanish abstract:

http://links.lww.com/IJEBH/A187
Comprehensive analysis across mammalian tissues and cells decipher the underlying mechanism of m6A specificity
Authors: Chai Guo-Shi , Chen Hong-Xuan , Ma Dong-Zhao , Ren Ze-Hui , Liu Xue-Hong , Luo Guan-Zheng
Published: April 2024

N6-methyladenine (m6A) stands out as the most prevalent internal chemical modification on mammalian mRNA, playing a vital role in diverse biological processes. Despite considerable advancements in individual cell line studies, the characteristics of m6A sites across distinct cell lines or tissues remain elusive. In this study, we have successfully identified approximately 1.5 million high-confidence m6A sites in human and mouse cell lines or tissues using published m6A-seq data. By categorizing m6A sites into different consistency levels, we observe that those of high consistency are notably enriched near the stop codon. Furthermore, they exhibit a higher likelihood of interaction with known m6A binding proteins such as YTHDF1-3, RBM15, YTHDC1, and IGF2BP1, thereby influencing gene expression homeostasis. Additionally, these sites display a higher CpG density in the promoter region of the genes they mark, with METTL3 demonstrating a preference for binding to the promoter region of its marked genes. m6A sites of low consistency levels, including unique m6A sites, show a significant enrichment near the start codon. These sites are more prone to binding by newly discovered m6A-binding proteins such as DDX3X, PRPF8, and EIF3G. The identification of these distinct features of m6A sites lays a foundational understanding for unraveling the functional roles of m6A.
Photon-photon correlation of condensed light in a microcavity
Authors: Tang Yijun , Dhar Himadri S. , Oulton Rupert F. , Nyman Robert A. , Mintert Florian
Published: April 2024

The study of temporal coherence in a Bose-Einstein condensate of photons can be challenging, especially in the presence of correlations between the photonic modes. In this work, we use a microscopic, multimode model of photonic condensation inside a dye-filled microcavity and the quantum regression theorem to derive an analytical expression for the equation of motion of the photon-photon correlation function. This allows us to derive the coherence time of the photonic modes and identify a nonmonotonic dependence of the temporal coherence of the condensed light with the cutoff frequency of the microcavity.

Published by the American Physical Society
2024
Out for Blood: Tyler Shultz and Theranos
Authors: Harris Jared D. , Slover Samuel L. , Agle Bradley R. , Romney George W. , Mead Jenny , Scoville Jimmy
Published: April 2024

In early 2014, recent Stanford University graduate Tyler Shultz was in a quandary. He had been working at Theranos, a blood-diagnostic company founded by Elizabeth Holmes, a Stanford-dropout wunderkind, for almost a year. Shultz had learned enough about the company to realize that its practices and the efficacy of its much-touted finger-prick blood-testing technology were questionable and that the company was going to great lengths to hide this fact from the public and from regulators.

Theranos and Holmes were Silicon Valley darlings, enjoying positive press and lavish attention from potential investors and technology titans alike. Just as companies like PayPal had revolutionized the stagnant payments industry and Uber had upended the for-hire transportation sector, Theranos had been positioned as the latest technology firm to substantially disrupt yet another mature sector: the medical laboratory business. By the start of 2014, the company had raised more than $400 million in funding, and had an estimated market valuation of $9 billion.

Shultz's situation was exacerbated by the fact that his grandfather, the highly respected former US Secretary of State George Shultz, was on the Theranos board and was one of Elizabeth Holmes's biggest supporters.

But Tyler Shultz worried about the customers he was convinced were receiving highly unreliable and often inaccurate blood-test results. With so much at stake, Shultz wondered how he should proceed. Should he raise his concerns with the firm's investors? Blow the whistle externally? Report to industry regulators? Go away quietly?

This case and its subsequent four brief follow-up cases are based largely on interviews with Tyler Shultz, and outline the dilemma he faced and the various steps he would take both to extricate himself from his unsavory position and let the public know the full extent of the deception at Theranos.

Five optional handouts are available to instructors to further discussion after the case has been debriefed. The handouts serve as additional decision points for the students if your class time permits.
OYO Hotels USA: Coming to America
Authors: Weiss Elliott N. , Wight Oliver , Maiden Stephen E.
Published: April 2024

This case studies the growth of OYO Hotels (OYO) to illustrate the operational processes necessary to succeed in the service sector. The case allows for a discussion of employee- and customer-management systems, tech-driven solutions, and profit drivers. The material unfolds OYO's growth and its solution for making economy hotels discoverable and bookable online.

The case raises a series of questions around OYO's business model, its ability to translate across global markets, and growth potential. It has been successfully taught in a second-year MBA class on the management of service operations.
The Panic of 2008 and Brexit: Regional Integration versus Nationalism
Authors: Bruner Robert F. , Emeritus Dean , Hare Kevin
Published: April 2024

In June 23, 2016, voters in the United Kingdom have just approved a referendum calling for leaving the European Union. The case describes the motives for European integration, the rise of separatist movements in the United Kingdom and elsewhere, and the referendum process itself.

The purpose of this case is to provide a contemporary counterpoint to a discussion of the economic and political motivations for the American Civil War. Dominant themes highlighted here are economic nationalism, political nationalism, cultural centrism and ethnocentrism, and populism.
Ratios Tell a Story—2019
Authors: Haskins Mark E.
Published: April 2024

This short case challenges students to review an array of corporate financial metrics and to match them to one of 13 listed industries. As such, students must use their intuition and common sense pertaining to the distinctive characteristics of, and the key differences between, the 13 named industries, and then identify the financial metrics that are most indicative of those traits.
Twitter's capacity to forecast tourism demand: the case of way of Saint James
Authors: Mendieta-Aragón Adrián , Navío-Marco Julio , Garín-Muñoz Teresa
Published: April 2024

Purpose

Radical changes in consumer habits induced by the coronavirus disease (COVID-19) pandemic suggest that the usual demand forecasting techniques based on historical series are questionable. This is particularly true for hospitality demand, which has been dramatically affected by the pandemic. Accordingly, we investigate the suitability of tourists’ activity on Twitter as a predictor of hospitality demand in the Way of Saint James – an important pilgrimage tourism destination.

Design/methodology/approach

This study compares the predictive performance of the seasonal autoregressive integrated moving average (SARIMA) time-series model with that of the SARIMA with an exogenous variables (SARIMAX) model to forecast hotel tourism demand. For this, 110,456 tweets posted on Twitter between January 2018 and September 2022 are used as exogenous variables.

Findings

The results confirm that the predictions of traditional time-series models for tourist demand can be significantly improved by including tourist activity on Twitter. Twitter data could be an effective tool for improving the forecasting accuracy of tourism demand in real-time, which has relevant implications for tourism management. This study also provides a better understanding of tourists’ digital footprints in pilgrimage tourism.

Originality/value

This study contributes to the scarce literature on the digitalisation of pilgrimage tourism and forecasting hotel demand using a new methodological framework based on Twitter user-generated content. This can enable hospitality industry practitioners to convert social media data into relevant information for hospitality management.
The rise of Indo-German collaborative research: 1990–2022
Authors: Mir Aasif Ahmad , Smirnova Nina , Jeyshankar Ramalingam , Mayr Phillip
Published: April 2024

Purpose

This study aims to highlight the growth and development of Indo-German collaborative research over the past three decades. Moreover, this study encompasses an in-depth examination of funding acknowledgements to gain valuable insights into the financial support that underpins these collaborative endeavours. Together with this paper, the authors provide an openly accessible data set of Indo-German research papers for further and reproducible research activities (the “Indo-German Literature Dataset”).

Design/methodology/approach

The data were retrieved from the Web of Science (WoS) database from the year 1990 till the 30th of November 2022. A total of 36,999 records were retrieved against the used query. Acknowledged entities were extracted using a named entity recognition (NER) model specifically trained for this task. Interrelations between the extracted entities and scientific domains, lengths of acknowledgement texts, number of authors and affiliations, number of citations and gender of the first author, as well as collaboration patterns between Indian and German funders were examined.

Findings

The study reveals a consistent and increasing growth in the publication trend over the years. The study brings to light that Physics, Chemistry, Materials Science, Astronomy and Astrophysics and Engineering prominently dominate the Indo-German collaborative research. The USA, followed by England and France, are the most active collaborators in Indian and German research. Largely, research was funded by major German and Indian funding agencies, international corporations and German and American universities. Associations between the first author’s gender and acknowledged entity were observed. Additionally, relations between entity, entity type and scientific domain were discovered.

Practical implications

The study paves the way for enhanced collaboration, optimized resource utilization and societal advantages by offering a profound comprehension of the intricacies inherent in research partnerships between India and Germany. Implementation of the insights gleaned from this study holds the promise of cultivating a more resilient and influential collaborative research ecosystem between the two nations.

Originality/value

The study highlights a deeper understanding of the composition of the Indo-German collaborative research landscape of the past 30 years and its significance in advancing scientific knowledge and fostering international partnerships. Furthermore, the authors provide an open version of the original WoS data set. The Indo-German Literature Data set consists of 22,844 papers from OpenAlex and is available for related studies like literature studies and scientometrics.
How does governance quality affect the shadow economy-sustainable development nexus? New insights from a dynamic threshold analysis
Authors: Assidi Nadia , Nouira Ridha , Saafi Sami , Abdelfattah Walid , Ben Mim Sami
Published: April 2024

Purpose

The purpose of this study is to assess the impact of the shadow economy on three sustainable development indicators while considering the moderating effect of the governance quality, and to highlight the non-linearity of the considered relationship.

Design/methodology/approach

A sample of 82 countries covering the period from 1996 to 2017. The dynamic first-differenced generalized method of moments (FD-GMM) panel threshold model is implemented to control for non-linearity.

Findings

The shadow economy hinders sustainable development in countries with low-governance quality, while the opposite result holds in countries with high-governance quality. The critical thresholds triggering the switch from one regime to another vary across the sustainable development indicators. Boosting growth requires enhancing the legal system and the economic dimension of governance, while promoting environmental quality requires the implementation and enforcement of specific environment-friendly regulations.

Originality/value

The study addresses non-linearity and the moderating effect of governance quality. The use of six governance indicators allows to gauge the ability of each governance dimension to curb the negative effects of the shadow economy. Considering the three objectives of sustainable development allows to identify specific policy recommendations for each of them.
Modelling the enablers of productivity of enterprise-level Agile software development process using modified TISM approach
Authors: Sathe Chaitanya Arun , Panse Chetan
Published: April 2024

Purpose

This study aims to examine the enablers of productivity of enterprise-level Agile development process using modified total interpretative structural modeling (TISM). The two main objectives of the current study are to determine the variables influencing enterprise-level agile development productivity and to develop modified TISM for the corresponding components.

Design/methodology/approach

To identify enablers of the productivity of enterprise-level agile software development process a literature review and opinions of domain experts were collected. A hierarchical relationship among variables that show direct and indirect influence is created using the modified TISM (M-TISM) technique with Cross Impact Matrix-Multiplication Applied to Classification analysis. This study examined and analyzed the relationships between the determinants within the enterprise using a M-TISM technique.

Findings

With the literature review, the study could identify ten enabling factors of the productivity of Agile development process at the enterprise level. Results depict that program increment (PI) planning and scalable backlog management, continuous integration and continuous delivery (CI/CD), agile release trains (ART), agile work culture, delivery excellence, lean and DevOps practices, value stream mapping (VMS), team skills and expertise, collaborative culture, agile coaching, customer engagement have an impact on the productivity of enterprise-level Agile development process. The results show that team collaboration, agile ways of working and customer engagement have a greater impact on productivity improvement for enterprise-level Agile development process.

Research limitations/implications

The developed model is useful for organizations employing scaled Agile development processes in software development. This study provides a recommended listing of key enablers, that may enable productivity improvements in the Agile development process at the enterprise level. Strategists should focus on team collaboration and Agile project management. This study offers a modified TISM model to academicians to help them understand the effects of numerous variables on maintaining the productivity of an enterprise-level Agile. The identified characteristics and their hierarchical structure can help project managers during the execution of Agile projects at the enterprise level, more effectively, increasing their success and productivity.

Originality/value

The study addresses the gap in the literature by interpretative relationships between the identified enabling factors. The model validation is carried out by a panel of nine experts from several information technology organizations deploying Agile software development at the enterprise level. This unique method broadens the knowledge base in Agile software development at scale and provides project managers and practitioners with a practical foundation.
The determinants of job satisfaction and auditors' performance in the Saudi context
Authors: Hakami Tahani Ali
Published: April 2024

Purpose

This study aims to examine the relationship between internal and external factors and job satisfaction, and between job satisfaction and auditors’ performance.

Design/methodology/approach

This research used deductive approach. Data was gathered from 83 auditors in the Saudi Organisation for Certified Public Accountants (SOCPA) database. By implementing the partial least squares-structural equation modelling (PLS-SEM) technique, the suggested hypotheses were examined.

Findings

The results show that internal factors, i.e., achievement, advancement, recognition and growth, significantly impact job satisfaction. Subsequently, the external factors, i.e., company policies, relationship with a peer and relationship with supervisor, significantly impact job satisfaction. In contrast, work security has no relationship with job satisfaction. Furthermore, job satisfaction is a significant driver for auditors' performance.

Research limitations/implications

This research sheds light on the relationships between internal and external factors, job satisfaction and auditors' performance in the Saudi context. It would be interesting to investigate these relationships in a different setting, such as a different country, time or industry. Future studies should broaden the sample frame to include different types of employees to obtain more generalisable results.

Practical implications

This study may help managers of auditing departments formulate appropriate strategies and design effective programs to increase the level of job satisfaction between auditors by enhancing such factors, which will lead to improving the auditors' performance.

Originality/value

This research provide an empirical evidence to support the theoretical assumptions of Herzberg's which is much needed.
Impact of community service on university performance and efficiency
Authors: Sondari Mery Citra , Hermanu Adhi Indra , Nurlaeli Leli , Artisheila Deis Savitri
Published: April 2024

Purpose

This study aims to analyze the effectiveness and efficiency of research-based community service programs in Indonesia that used government funds in 2017–2021.

Design/methodology/approach

The design of this research is a quantitative research method using a data envelopment analysis to evaluate 370 leading universities in Indonesia. Furthermore, six analytical models were considered to compare effectiveness and efficiency between universities. It involved two resource (budget and staff academic involved), three output (intellectual property, prototype and publication) and three outcome variables (economic impact, social impact and capacity building).

Findings

The findings showed that several universities are considered necessary, with great potential to increase output and outcome efficiency in community involvement. The study mapped and divided the position of 370 universities for additional information. The effectiveness aspect provides another perspective in assessing the performance of tertiary institutions in Indonesia and can be an option for evaluating research performance to improve the quality of output.

Originality/value

The authors use data from research and community service management information systems used, both the resources used and the results. Efficiency and effectiveness of 370 universities were compared in this study, including comparing their position on the previous assessment with the assessment of the results of this study. Approach to the concept of Mandl et al. (2008) regarding the relationship between input, output and outcome as the main component of the indicators, the authors apply to analyze efficiency and effectiveness.
A systematic literature review of crisis management in online public opinion: evolutionary path and implications for China
Authors: Zhang Lu , Dong Pu , Zhang Long , Mu Bojiao , Yang Ahui
Published: April 2024

Purpose

This study aims to explore the dissemination and evolutionary path of online public opinion from a crisis management perspective. By clarifying the influencing factors and dynamic mechanisms of online public opinion dissemination, this study provides insights into attenuating the negative impact of online public opinion and creating a favorable ecological space for online public opinion.

Design/methodology/approach

This research employs bibliometric analysis and CiteSpace software to analyze 302 Chinese articles published from 2006 to 2023 in the China National Knowledge Infrastructure (CNKI) database and 276 English articles published from 1994 to 2023 in the Web of Science core set database. Through literature keyword clustering, co-citation analysis and burst terms analysis, this paper summarizes the core scientific research institutions, scholars, hot topics and evolutionary paths of online public opinion crisis management research from both Chinese and international academic communities.

Findings

The results show that the study of online public opinion crisis management in China and internationally is centered on the life cycle theory, which integrates knowledge from information, computer and system sciences. Although there are differences in political interaction and stage evolution, the overall evolutionary path is similar, and it develops dynamically in the “benign conflict” between the expansion of the research perspective and the gradual refinement of research granularity.

Originality/value

This study summarizes the research results of online public opinion crisis management from China and the international academic community and identifies current research hotspots and theoretical evolution paths. Future research can focus on deepening the basic theories of public opinion crisis management under the influence of frontier technologies, exploring the subjectivity and emotionality of web users using fine algorithms and promoting the international development of network public opinion crisis management theory through transnational comparison and international cooperation.
A scoping review of green Internet of Things in construction and smart cities: current applications, adoption strategies and future directions
Authors: Ullah Fahim , Olatunji Oluwole , Qayyum Siddra
Published: April 2024

Purpose

Contemporary technological disruptions are espoused as though they stimulate sustainable growth in the built environment through the Green Internet of Things (G-IoT). Learning from discipline-specific experiences, this paper articulates recent advancements in the knowledge and concepts of G-IoT in relation to the construction and smart city sectors. It provides a scoping review for G-IoT as an overlooked dimension. Attention was paid to modern circularity, cleaner production and sustainability as key benefits of G-IoT adoption in line with the United Nations’ Sustainable Development Goals (UN-SDGs). In addition, this study also investigates the current application and adoption strategies of G-IoT.

Design/methodology/approach

This study uses the Preferred Reporting Items for Systematic and Meta-Analyses (PRISMA) review approach. Resources are drawn from Scopus and Web of Science repositories using apt search strings that reflect applications of G-IoT in the built environment in relation to construction management, urban planning, societies and infrastructure. Thematic analysis was used to analyze pertinent themes in the retrieved articles.

Findings

G-IoT is an overlooked dimension in construction and smart cities so far. Thirty-three scholarly articles were reviewed from a total of 82 articles retrieved, from which five themes were identified: G-IoT in buildings, computing, sustainability, waste management and tracking and monitoring. Among other applications, findings show that G-IoT is prominent in smart urban services, healthcare, traffic management, green computing, environmental protection, site safety and waste management. Applicable strategies to hasten adoption include raising awareness, financial incentives, dedicated work approaches, G-IoT technologies and purposeful capacity building among stakeholders. The future of G-IoT in construction and smart city research is in smart drones, building information modeling, digital twins, 3D printing, green computing, robotics and policies that incentivize adoption.

Originality/value

This study adds to the normative literature on envisioning potential strategies for adoption and the future of G-IoT in construction and smart cities as an overlooked dimension. No previous study to date has reviewed pertinent literature in this area, intending to investigate the current applications, adoption strategies and future direction of G-IoT in construction and smart cities. Researchers can expand on the current study by exploring the identified G-IoT applications and adoption strategies in detail, and practitioners can develop implementation policies, regulations and guidelines for holistic G-IoT adoption.
A comprehensive assessment of wind energy potential and wind farm design in a coastal industrial city
Authors: AlQahtani Ali M.
Published: April 2024

Purpose

Jubail Industrial City is one of the largest industrial centers in the Middle East, offering potential opportunities for renewable energy generation. This research paper presents a comprehensive analysis of the wind resources in Jubail Industrial City and proposes the design of a smart grid-connected wind farm for this strategic location.

Design/methodology/approach

The study used wind data collected at three different heights above ground level – 10, 50 and 90 m – over four years from 2017 to 2020. Key parameters, such as average wind speeds (WS), predominant wind direction, Weibull shape, scale parameters and wind power density (WPD), were analyzed. The study used Windographer, an exclusive software program designed to evaluate wind resources.

Findings

The average WS at the respective heights were 3.07, 4.29 and 4.58 m/s. The predominant wind direction was from the north-west. The Weibull shape parameter (k) at the three heights was 1.77, 2.15 and 2.01, while the scale parameter (c) was 3.36, 4.88 and 5.33 m/s. The WPD values at different heights were 17.9, 48.8 and 59.3 W/m2, respectively.

Originality/value

The findings suggest that Jubail Industrial City possesses favorable wind resources for wind energy generation. The proposed smart grid-connected wind farm design demonstrates the feasibility of harnessing wind power in the region, contributing to sustainable energy production and economic benefits.
A spontaneous hyperglycaemic cynomolgus monkey presents cognitive deficits, neurological dysfunction and cataract
Authors: Huang Hongdi , Pu Jianglin , Zhou Yufang , Fan Yang , Zhang Yali , Li Yanling , Chen Yangzhuo , Wang Yun , Yu Xiaomei , Dmitry Bulgin , Zhou Zhu , Wang Jianhong
Published: April 2024

Chronic hyperglycaemia is a chief feature of diabetes mellitus and complicates with many systematic anomalies. Non‐human primates (NHPs) are excellent for studying hyperglycaemia or diabetes and associated comorbidities, but lack behavioural observation. In the study, behavioural, brain imaging and histological analysis were performed in a case of spontaneously hyperglycaemic (HGM) Macaca fascicularis. The results were shown that the HGM monkey had persistent body weight loss, long‐term hyperglycaemia, insulin resistance, dyslipidemia, but normal concentrations of insulin, C‐peptide, insulin autoantibody, islet cell antibody and glutamic acid decarboxylase antibody. Importantly, an impaired working memory in a delayed response task and neurological dysfunctions were found in the HGM monkey. The tendency for atrophy in hippocampus was observed by magnetic resonance imaging. Lenticular opacification, lens fibres disruptions and vacuole formation also occurred to the HGM monkey. The data suggested that the spontaneous HGM monkey might present diabetes‐like characteristics and associated neurobehavioral anomalies in this case. This study first reported cognitive deficits in a spontaneous hyperglycaemia NHPs, which might provide evidence to use macaque as a promising model for translational research in diabetes and neurological complications.
Supporting equitable care of patients transferred from police watch‐houses to the emergency department: A qualitative study of the perspectives of emergency doctors
Authors: Brandenburg Caitlin , Thomas Stuart DM , Lincoln Cathy , Somerville Annabel , Heffernan Ed , Kinner Stuart A , Byrnes Joshua , Gardiner Paul , Davidson Peter , Daley Nathan , Green David , Crilly Julia
Published: April 2024

Objective

People detained in short‐term police custody often have complex health conditions that may necessitate emergency care, yet little is known about their management in EDs. The present study aimed to understand ED doctors' experiences and perceptions regarding the appropriateness and management of detainee transfers from police watch‐houses to the EDs.

Methods

A qualitative descriptive study, using semi‐structured interviews undertaken with ED doctors working in five purposively sampled EDs across Queensland, Australia. Data were analysed using inductive content analysis.

Results

Fifteen ED specialists and trainees participated. Participants reported that their overarching approach was to provide equitable care for watch‐house detainees, as they would for any patient. This equitable approach needed to be responsive to complicating factors common to this population, including presence of police guards; restraints; complexity (physical/mental/social) of presentation; reliance on police to transport; ED doctors' often limited understanding of the watch‐house environment; justice processes and uncertain legal disposition; communication with the watch‐house; and detainees misreporting symptoms. Thresholds for assessment and treatment of detainees were contextualised to the needs of the patient, ED environment, and imperatives of other relevant agencies (e.g. police). Participants often relied on existing strategies to deliver quality care despite challenges, but also identified a need for additional strategies, including education for ED staff; improved communication with watch‐houses; standardised paperwork; extended models of watch‐house healthcare; and integrated medical records.

Conclusions

Providing equitable healthcare to patients transported from watch‐houses to the EDs is challenging but essential. Numerous opportunities exist to enhance the delivery of optimal care for this underserved population.
Childhood obesity in the ED: A prospective Australian study
Authors: Marsh Rachel , Gill Stephen , Lowry Nicole , Hayden Georgina , Ryan Matthew , Gwini Stella‐May , Allender Steven , Stella Julian
Published: April 2024

Objective

To determine (i) the prevalence of overweight and obesity among children presenting to all EDs in a large regional Australian city and (ii) whether age, sex, socioeconomic status (SES) or hospital setting (public vs private) were associated with overweight and obesity.

Methods

This prospective observational study included children aged ≥2 and <18 years who presented to any of three EDs over an 18 month period who had their height and weight measured. Age, sex and residential postcode were collected. Weight category was determined by sex and age standardised body mass index (BMI) z‐score. Weight category was assessed by sex, age, SES and hospital setting with chi‐squared tests, and ordinal logistic regression with cluster sandwich error estimators. Results were reported using odds ratios (OR) with 95% confidence intervals (CI).

Results

Data were collected for 3827 children, of which 11.6% were obese and 19.8% overweight. The prevalence of obesity was highest in those aged 8–14 years and in those from lower SES postcodes. The likelihood of obesity was higher in the public than the private hospitals (OR 0.66, 95% CI 0.51–0.86), whereas the likelihood of overweight was similar (OR 1.00, 95% CI 0.83–1.22).

Conclusions

Almost one‐third of children who presented to EDs were overweight or obese. Obesity was particularly high in those aged 8–14 years and those from lower SES postcodes. In the evolving obesity crisis, the high proportion of children presenting to EDs above a healthy weight might represent an opportunity for EDs to identify and refer children for body weight and lifestyle management.
Massive peritoneal inclusion cyst with secondary abscessation
Authors: Pappas Christian P. , Xu Zhengchao , Hicks Gabrielle , Sarofim Mina , Wijayawardana Ruwanthi , Morris David L.
Published: April 2024

Peritoneal inclusion cysts are rare intra‐abdominal cystic lesions of controversial pathogenesis and nomenclature. Postulated to be of neoplastic or reactive origin, they are characterised by progressive expansion and variable symptomatology in classically reproductive‐aged females. Local recurrence is frequent while malignant transformation is plausible. Herein, we review a presentation of a massive peritoneal inclusion cyst with secondary abscessation and septic shock in a 58‐year‐old female, reviewing the available literature to highlight the potential acuity of this pathology, the standard of surgical care, and the need for caution by treating surgeons in its evaluation as an entirely benign process.
Modest effect of differential dietary vitamin A intake on the pathogenesis of alcohol‐associated liver disease
Authors: Ferdouse Afroza , Clugston Robin D.
Published: April 2024

Background

Chronic alcohol consumption is a major public health issue. The primary organ damaged by alcohol abuse is the liver, leading to alcohol‐associated liver disease (ALD). ALD begins with hepatic steatosis and can progress to fibrosis and cirrhosis; however, we have an incomplete understanding of ALD pathogenesis. Interestingly, the liver is also the major organ for vitamin A metabolism and storage, and ALD has previously been linked with altered hepatic vitamin A homeostasis. We hypothesize that alcohol‐induced vitamin A depletion disrupts its normal function in the liver, contributing to the pathogenesis of ALD. To test this hypothesis, we postulated that adding copious vitamin A to the diet might alleviate ALD, and conversely, that a vitamin A deficient diet would worsen ALD.

Methods

We conducted two dietary intervention studies in mice comparing deficient (0 IU/g diet) and copious (25 IU/g diet) dietary vitamin A intake versus control (4 IU/g diet), using the NIAAA chronic‐binge model of ALD. Hepatic steatosis was assessed using histopathological and biochemical approaches. Tissue Vitamin A levels were measured using high‐performance liquid chromatography. Markers of ALD, hepatic inflammation and lipid metabolism were analyzed by the quantitative polymerase chain reaction and western blotting.

Results

As expected, a 0 IU/g Vitamin A diet decreased, and a 25 IU/g Vitamin A diet increased hepatic Vitamin A stores. However, alcohol induced changes in hepatic triglyceride levels, markers of hepatic lipid metabolism, inflammation and fibrosis were not significantly different in mice consuming a copious or deficient vitamin A diet compared to control.

Conclusions

Altered vitamin A intake and hepatic vitamin A storage have a minor effect on the pathogenesis of ALD. Thus, given the known link between altered retinoic acid signaling and ALD, future studies that further explore this linkage are warranted.