bluuebunny/crossref_metadata_2025 huggingface dataset:
THE EFFECT OF PERSONAL PROTECTIVE EQUIPMENT USE ON NURSES’ PERCEIVED INDIVIDUALIZED CARE IN THE COVID-19 PANDEMIC
Authors: DOĞAN Aysel , ZENGİN AYDIN Leyla , YILMAZ Leyla
Published: October 2022

This research was conducted between January and March 2021 as a descriptive, cross-sectional and correlational study to determine the effect of personal protective equipment use on nurses' perceptions of individualized care during the COVID-19 pandemic. The population of the study consisted of 130 nurses working in the COVID-19 clinics of a university hospital in a province in the east of Turkey, and the sample consisted of 127 nurses who agreed to participate in the study. Data were collected using the personal information form and the Individualized Care Scale-Nurse version A. While there was a statistically significant relationship between nurses' gender, education level and the mean total score of the Individualized Care Perception Scale-Nurse A version (p
İleri Oksidasyon Proseslerinin Sızıntı Sularının Arıtımında Kullanımı
Authors: ATMACA Kasım , BEYAZIT Nevzat
Published: October 2022

Bu çalışmada, ileri oksidasyon prosesleri olarak bilinen, Fenton, elektro-Fenton ve foto-elektro-Fenton’un temel mekanizmaları ve sızıntı suyu arıtımında seçilen deneysel çalışma parametrelerinin bu proseslerin verimliliğine etkileri tartışılmıştır. Sızıntı suyu arıtımı ile ilgili deneysel çalışmalar, organik kirleticilerin hızlı oksidatif bozunmasını sağlamak için ileri oksidasyon proseslerinin kullanılabileceğini göstermiştir. Bu nedenle, sızıntı suyunun arıtımında, Fenton ve ilgili proseslerin kullanımı literatürde yaygın olarak tartışılmaktadır. Fenton reaksiyonu sırasında, asidik ortamda hidroksil radikalleri (OH●) üretmek için hidrojen peroksit (H2O2) demir tarafından aktive edilir ve oluşan OH● sızıntı suyundaki dirençli organik bileşikleri giderir. Ülkemizde yürürlükte olan Su Kirliliği ve Kontrolü Yönetmeliği'nde ifade edilen deşarj standartları çoğunlukla sağlanmasa da ileri oksidasyon proseslerinin çok yüksek çözünmüş kirletici konsantrasyonlarını azaltmada oldukça etkili olduğu anlaşılmaktadır. Bu nedenle sızıntı suyu arıtımında bu tür tekniklerin ön arıtma veya arıtma sonrası şeklinde başka bir arıtma ile birlikte kullanılması tavsiye edilir.
Direct and indirect pathways for environmental drivers of hatching success in the loggerhead sea turtle
Authors: Whitesell MJ , Hunter EA , Rostal DC , Carroll JM
Published: October 2022

Nest site selection has consequences for hatching success by mediating the temperature and moisture conditions that eggs experience during the incubation period. Understanding the potentially complex pathways by which nest placement influences these abiotic mediators, and therefore hatching success, is important for predicting which nests will be successful and which may require management action. We studied the effects of loggerhead sea turtle (Caretta caretta) nest site selection on hatching success by linking nest placement characteristics to hatching success through a structural equation model. We monitored 170 nests on Ossabaw Island, Georgia, during the summers of 2017 and 2018 and tracked nest conditions throughout the incubation period. Temperature had a complex effect on hatching success—nests had higher hatching rates if they were exposed to higher mean temperatures but also if they experienced both extremely high (>34°C) and extremely low (<26.5°C) temperatures, suggesting that temperature variability plays a role in determining nest outcomes beyond the mean temperature. Likewise, hatching success declined with a higher incidence of nests being inundated by tides. We found that nests placed at the highest elevations had the highest hatching success rates, likely because those nests had a much lower chance of being washed over by high tides and had higher mean temperatures. Nests were also more successful when placed in greater amounts of vegetation, again because vegetated nests were generally warmer and were associated with fewer washover events. These results shed light on the mechanisms behind selection for certain nest site characteristics and can guide the relocation of nests as a conservation action.
Defaunation by deoxygenation: efficacy and divergent responses of estuarine macroinvertebrates
Authors: Cronin-O’Reilly S , Wells NS , McCallum R , Hallett CS , Tweedley JR , Valesini FJ , Eyre BD
Published: October 2022

Understanding the influence of macroinvertebrates on ecosystem function often relies on experimental defaunation with methods that remove fauna through minimal sample disturbance. Defaunation is challenging and can lead to confounding effects and/or loss of empirical information when unsuccessful. We evaluated the ability of a deoxygenation treatment to remove macroinvertebrates from sediment cores collected in 2 regions of a microtidal estuary. Only 1 of 16 cores was fully defaunated following 3 deoxygenation cycles. To counteract confounding effects of partial defaunation, we quantified the biomass remaining in each core and used these data as a covariate in statistical models. The unremoved biomass had, in some cases, significant effects on alkalinity fluxes, with positive linear relationships evident, and net phosphate fluxes. The community in the upper estuary that regularly experiences hypoxia exhibited stronger sediment emergence responses (82-100%). The remaining fauna were spread equally among annelids, molluscs and arthropods in abundance, although arthropods dominated the biomass. In contrast, fewer macroinvertebrates emerged from sediments from the lower estuary (47-89%), with most of the remaining biomass and abundance being annelids and molluscs. These findings suggest that estuarine taxa have divergent responses to hypoxia and that regional communities are variably prone to eradication of sensitive taxa. Our study shows how the use of defaunation by deoxygenation can create systematic bias, particularly when comparing areas with disparate in situ oxygen regimes, and provides a way to quantitively account for partial defaunation without sacrificing statistical power or using overly destructive methods.
Change of ecological strategies in the phytoplankton community of the north-eastern part of the Black Sea during the annual cycle
Authors: Lifanchuk Anna V. , Fedorov Aleksey V.
Published: October 2022

The main ecological strategies of phytoplankton community structure of the north-eastern part of the Black Sea were revealed. In the spring period, small cell size of diatoms predominate, when the concentrations of elements of mineral nutrition are high, and the light fluxes are far below the maxima (R-strategists). At the end of the spring – early summer the main role is played by coccolithophores, which are tolerant to limited content of mineral nutrition elements in the environment (S-strategists). In summer prevail large cell species of diatom under high insolation conditions and periodic wind-wave mixing of the upper water layer (C'-strategists).
Why at the beginning of this century in the north-eastern part of the Black Sea kopepoda Oithona nana Giesbr. disappeared?
Authors: Lukasheva Taisia A. , Moskalenko Lydia V. , Pautova Larisa A. , Melnikov Vasily A. , Silkin Vladimir A.
Published: October 2022

A new hypothesis is proposed for the disappearance of copepod population Oithona nana from the plankton of the Blue Bay of the northeastern part of the Black Sea. This hypothesis is related to the influence of dynamic factor (wind) on the occurrence of this species. Not excluding the determining influence of the Mnemiopsis leidyi ctenophore predator press on Oithona dynamics, this hypothesis considers the dominant direction and wind speed as an additional factor affecting the growth rate. The population of Oithona occurred in zooplankton community during the period of predominance of the northeastern and southeastern types of atmospheric processes over the water area until 2002. The change in types of atmospheric processes in 2002 to the eastern and southern led to a catastrophic decrease in the population of this crustacean, until its complete disappearance. This factor can act directly by concentrating, or flushing out the population from the coastal zone, or changing the food resource through a decreasing of the total biomass of phytoplankton and an increasing in the portion of coccolithophores that replace more valuable in nutrition diatoms. The appearance of a new species with similar food preferences is associated with the inversion of atmospheric processes that lead to the former state of the hydrological structure and food resource – a return to the dominance of diatoms and an increase in the biomass of phytoplankton as a whole.
Introduction
Authors: Cachopo João Pedro , Nickleson Patrick , Stover Chris
Published: October 2022

The co-authors provide an overview of the absence and presence of music in Rancière’s thought, proposing a musicality present at all points even when music, in particular, may not be.
‘Rip it up and start again’: Reconfigurations of the Audible under the Aesthetic Regime of the Arts
Authors: Frappier Daniel
Published: October 2022

Rancière’s aesthetic regime, in clear opposition to the solidly established hierarchies of earlier regimes, is based on the blend, if not the identity, of contraries: the noble and the vulgar, the active and the passive, the conscious and the unconscious. Building on these reflections, Frappier proposes to retrace some of the debates and displacements that, since the nineteenth century, blur the lines between thought and non-thought, art and non-art, music and noise. He moves from Novalis’s “everything speaks” to John Cage’s “[t]here is no such thing as silence,” from Victor Hugo's “harmony of the contraries” to Richard Meltzer's rock “totality,” and from Gustave Courbet's “negation of the ideal” to the radical refusals of no wave music.
A Lesson in Low Music
Authors: Nickleson Patrick
Published: October 2022

In Althusser’s Lesson, Rancière disrupts his teacher’s language to introduce an uncommonly concrete musical concept: the “low music.” In this essay, Nickleson builds up this passing concept to draw attention to an unnoticed, slanted rhyme in Rancière’s work between the bruit of noise and the abrutir of stultification, arguing that a Rancièrian musicological method must refuse any form of listening or analysis that begins by stultifying audiences.
Rancière and Improvisation: Reading Contingency in Music and Politics
Authors: DiPiero Dan
Published: October 2022

Dan DiPiero interrogates the aporia between improvisation as a politically emancipatory practice and the essential impossibility of its being so. Beginning by working within music-improvisational practices, he projects outward to consider the contingent aspects of social and political interaction. Music, in this sense, becomes a ground for thinking through the social.
Altai earthquake (2003) fault zone velocity structure - case study
Authors: Dergach P. A. , Yaskevich S. V. , Yablokov A. V.
Published: October 2022

This paper presents the results of seismic surveys in the epicentral zone of the Alaty earthquake (2003), conducted in the summer of 2021. The object of research was a fractured zone, which on the surface manifests itself as a rupture of the earth's surface with a width of 3-5, a depth of up to 1 and a length of about 200 meters. The main objective of the 2021 research was to study changes in the structure of the velocity section in the rupture zone, presumably associated with the degradation of the permafrost. As a result of processing records of refracted waves, a seismotomographic model for P-waves was obtained, and a seismic boundary was identified by the GRM method. As a result of processing surface wave recordings by MASW, one-dimensional S-wave sections were obtained for the left and right parts of the section. Interpretation of the results showed the presence of a huge unfrozen zone with a thickness of about 30 meters, which indicates an active process of degradation of the permafrost in this area.
Mercury in soils of intermountain depressions in the Western Baikal region
Authors: Lyapina E. Е.
Published: October 2022

The article presents original data on the gross concentration of Hg in soils of various types in the territory of the southwestern Baikal region. Quantitative estimates of Hg distribution over the area of intermountain depressions and slopes of mountain ranges have been obtained. The features of the distribution of Hg concentrations in the surface component of soils depending on the type of soils, granulometric composition, hydrolytic acidity, the sum of exchangeable bases, the degree of saturation with bases, pH, humus, CO, N, and humic acids were revealed. The forms of Hg occurrence in soils of different types are determined: the largest proportion of Hg is in the forms associated with organic complexes and exchangeable bases. The calculated indicators indicate an increased natural geochemical background of mercury in soils, which is associated with the territorial belonging to the Baikal rift zone.
Petroleum potential of Jurassic regional reservoirs in the Yenisei-Khatanga and adjacent Gydan petroleum-bearing areas
Authors: Shemin G. G. , Pervukhina N. V. , Glazyrin P. A.
Published: October 2022

The paper discusses methods and results of the petroleum potential quantification in regional Jurassic reservoirs within the Yenisei-Khatanga petroleum-bearing area (PBA) and eastern Gydan PBA. The structure and distributions of initial in-place hydrocarbons in reservoirs, petroleum-bearing regions, and by categories of reserves and resources are presented. The petroleum potential was assessed by a geological method from specific densities of HC reserves per unit area, on the basis of comprehensive analysis of tectonic, lithologic-facies and geochemical criteria for determination of petroleum potential. According to the author's estimates, the prognosed initial hydrocarbon resources in Jurassic reservoirs within the Yenisei-Khatanga and eastern Gydan PBR amount to 12505 million tons total hydrocarbon equivalent, which includes 10935 billion m (87.5%) gas, and 1570 million tons (12.5%) condensate.
Application of discrete element method to estimation of strength properties of elastic media
Authors: Chepelenkova V. D. , Lisitsa V. V.
Published: October 2022

Discrete element method uses the representation of simulated material as a group of individual particles being rigid bodies with a given set of elastic constants. This approach makes it possible to simulate processes accompanied by large deformations and discontinuities of the medium more efficiently than when using continuum methods. However, the main drawback of discrete element method is the lack of a direct correlation between particle parameters and elastic properties of the system as a whole, which makes it necessary to calibrate the model to match the real material. In this paper we present an implementation of the algorithm using discrete element method to simulate the behavior of solid materials leading to their fracturing. For the obtained model the influence of particle parameters on Young’s modulus and strength in uniaxial compression test was examined.
Seismic Analysis of a Multiscale Discrete Fracture System
Authors: Kolyukhin D. R. , Protasov M. I.
Published: October 2022

The work is devoted to the development and study of a statistical model of a discrete network of cracks at different spatial scales. The distribution of fracture centers is a fractal set, which is determined by a given value of the correlation fractal dimension D 2 . The fracture lengths are described by a power-law probability distribution with the corresponding value of the exponent α . The possibility to estimate these model parameters based on the corresponding seismic images is investigated.
Event localization results obtained by various processors in downhole microseismic monitoring and their analysis
Authors: Yaskevich S. V. , Duchkov A. A.
Published: October 2022

The paper compares the processing results of four different companies for the same amount of data. The main focus of the work is related to assessing the quality of building a velocity model of the medium. It turned out that the performers used quite different models from each other, and, accordingly, received different results from each other on the example of one of the events. We analyzed the quality of localization of perforation events in these models and the quality of timing, both for perforations and for one of the microseismic events.
Numerical simulation of filtration in a fractured-porous oil-saturated reservoir drilled on overbalance for various types of development
Authors: Petrov M. N. , Yeltsov I. N. , Nesterova G. V.
Published: October 2022

Structural features of fractured-porous reservoirs lead to the need to apply dual porosity/permeability models to correctly describe filtration and other processes in such media. The paper presents a model of an oil-saturated fractured-porous reservoir penetrated by overbalance drilling and an example of numerical calculation of the most important parameters. The model is based on the Barenblatt approach, when the systems of fractures and blocks are presented as continuous media connected by fluid exchange. In addition, unlike the known models, it takes into account the influence of deformation processes associated with reservoir development on filtration characteristics. The model allows for various assessments of filtration, flow and other parameters in various well operation modes, such as production or drilling.
Puzzling magnetic anomaly in the Barun-Khal valley (Olkhon region, western Gisbaikalia)
Authors: Kozhevnikov N. O.
Published: October 2022

The Brun-Khal valley is in the Olkhon region, northwest of the village of Chernorud. Since the end of the 70s. the valley and its surroundings has been studied with geophysical methods. During magnetic survey in the central part of the valley, some round-shaped magnetic anomalies were mapped the nature of which remains unclear. Especially unusual is a negative magnetic anomaly with an amplitude of more than 1200 nT and a width of about 50m. According to the simulation, the anomaly is caused by a vertical, negatively magnetized rod or a thin cylinder, the upper and lower edges of which are located at a depth of 17m and 50m, respectively. Presumably, the anomaly is due to a stock of igneous rocks that intruded into host rocks when the polarity of the geomagnetic field was negative.
Mechanism of sulfide ore flotation activation by precipitated lead xanthates
Authors: Gavrilova T. G.
Published: October 2022

The authors justify feasibility of sphalerite flotation activation by physisorbed products of interaction of heavy metals and ion xanthates as a case-study of activation with lead ethyl xanthate. It is shown that the collecting agent derivatives can remove the kinetic constraint of the particle-bubble attachment, i.e. they remove water from the interlayer between a mineral particle and a gas bubble. The spreading rate of the collector derivatives governs the rate of the interlayer removal, the induction time and the collectability of this type of adsorption. The tests reveal that the increase in pH from 7 to 10 accelerates spreading of ethyl precipitates of lead xanthate over water surface from 8.5 to 15 cm/s, which correlates with the flotation performance. Based on the mechanism of physisorption, the suppression of sphalerite flotation at higher concentrations of salts of heavy metals is explained.
Criterion for the transition of the fan control system to the mode of dynamic performance control
Authors: Zedgenizov D. V.
Published: October 2022

An algorithm for the transition of the automatic control system from the fan performance stabilization mode to the dynamic control mode is presented. The algorithm makes it possible to use the change in the closing angle of the air distribution regulator flaps and the regulation of the fan shaft speed to reduce the power required for ventilation of the subway.
Кelationship of the parameters of physico-chemical and sorp-tion processes with the emission of coal beds. part II: on the influence of the stages of metamorphism of natural coals on their metanic capacity
Authors: Kiryaeva T. A.
Published: October 2022

In this part of the article, based on the technologies of intelligent data processing (Data Mining), it is shown that the dispersion of the experimental da-ta on the release of volatile substances in depth is associated with the peculiarities of the manifestation of regional thermo-metamorphism of coals. It has been established that the most powerful factors influencing the methane capacity of coal are the depth of coal seams and the release of volatile substances, which is consistent with classical concepts.
Role of a physisorbed collecting agent in flotation of pyrite
Authors: Konovalov I. A.
Published: October 2022

The article addresses the role of products of interaction between xanthate and iron ions in flotation of pyrite at different pH values. It is shown that derivatives of butyl xanthate and iron chloride feature a high spreading rate at the gas-liquid interface and can contribute to removal of the kinetic constraint of the particle-bubble attachment. The effect on the rate of water removal from the interlayer between a mineral particle and a gas bubble depends on the ratio of concentrations and on pH values of the solution. The mechanism of physisorption of a collecting agent is used to explain the suppression of pyrite flotation in a pH-neutral medium and the increased floatability of pyrite in the alkaline range of pH.
About the primary smoke of the subway tunnel when a burning train stops in it
Authors: Lugin I. V.
Published: October 2022

The article is devoted to the study of aerodynamic processes occurring in a subway tunnel when a burning train stops in it. The dynamics of the deceleration of the air flow accelerated by the piston action of a moving train is investigated by computational modeling using the finite volume method. When gorenje trains in the tunnel, this flow carries toxic combustion products through the tunnel, thereby creating the primary smoke tunnel. The influence of the length of the tunnel section with a train and aerodynamic drag on the dynamics of air flow braking is considered. To accelerate the deceleration of the air flow, the use of smoke-retaining devices on the train is proposed, the effectiveness of their use is determined.
Numerical simulation of the airflow in a mine axial fan in reverse mode
Authors: Pervukhin D. O. , Kosykh P. V.
Published: October 2022

The article considers the numerical calculations of the air flow flow in an asian fan operating in reverse mode. The calculation was carried out in the ANSYS CFX. Fan of the TsAGI OV-103 aerodynamic scheme was considered, for which experimental aerodynamic characteristics are known. K-ε and SST turbulence models were used in the calculation. The dependences of the total fan pressure on the flow rate are obtained. For a single-stage Rotor+OGV scheme, the closest to experimental results were calculated using the SST model. For a two-stage Rotor+OGV+Rotor+OGV dependence of the total pressure is determined using the k-ε model. For such a scheme, axial velocity distributions in the outlet are calculated for different performance values.
Development of a methodology to research the influence of liquid nitrogen exposure on carbon material
Authors: Rybalkin L. A. , Serdyuk I. M.
Published: October 2022

Recently, studies, which are dedicated to the effect of cryogenic substances on the structure of coal, are gaining popularity. The impact of liquid nitrogen on coal leads to micro- and macrostructural disturbances in the continuity of coal due to drastic cooling of the moisture in the microcracks and pore space of the coal, while the volume of ice microcrystals increases. This approach provides the opportunity to treat the massif without additional injection of liquid agents into seams to create pressure to disintegrate it, unlike traditional methods of increasing the filtration surface in coal. Research work, which are presented in this field, are aimed at studying the multiplicity of increase in porosity and fracturing of coal in the process of single or multiple exposure to portions of liquid nitrogen. A distinctive feature of the ongoing research is the evaluation of the results of cryotreatment of samples by non-destructive methods of measuring the pore space. Thus, the conclusion about the change in permeability is made without direct measurements of the gas filtration rates in the samples. Changes shown by CT scans show an increase in the total number of open pores and channels, however they do not illustrate the increase in gas permeability in general. As a part of this work, we carried out a number of studies on axial gas filtration in dense coal samples, which were under controlled all-round loading. Preparatory work was carried out to dry the samples and further saturate them with moisture to identical values in the entire batch. A scheme for conducting experiments to study the effect of cryotreatment on the internal structure of coal using the methods of stationary axial gas filtration and NMR relaxometry is proposed. The development of this technique contributes to obtaining reliable data on the increase in the gas permeability of coal samples. The data can be useful in designing methods and approaches to increase the degree of degassing by treating degassing wells at coal mining enterprises.
Investigations of permafrost rocks by the TEM method at the Research Station «Samoylov Island»
Authors: Potapov V. V. , Zaplavnova A. A. , Kartozia A. A.
Published: October 2022

In the period from 07/05/2021 to 08/07/2021, a field survey was carried out near the Scientific Station «Samoylov Island ». Within the framework of this trip, measurements were carried out by the TEM method. The purpose of the research was to determine the thickness of permafrost on the island using the TEM technique. We previously estimated the permafrost thickness of Samoylov Island and its environs as 400-1000 m by using the MTS technique. The size of the generator loop was 200×200 m. The electromagnetic field registration was carried out by a single-turn loop measuring 20*20 meters with different spacings: - 100, 0, 100 meters from the center of the generator loop along with two profiles. The apparent resistivity curves obtained in the study area are divided into two types: curves with a high influence of induced polarization (IP) processes and without such a significant influence. According to the interpreting sections analysis, the permafrost thickness is about 700 meters. This result is shown in both sections. Also can be noted, that the TEM technique makes it possible to determine the geoelectric properties of the upper part of the section up to 50 meters deep.
Composition and magnetic properties of rocks of Zarechenskaya and Nikolskaya magnetic anomalies (East coast of Lake Baikal)
Authors: Saylymby D. Yu. , Vishnevsky A. V. , Dyadkov P. G.
Published: October 2022

The mineral composition of rock samples of the Zarechenskaya and Nikolskaya magnetic anomalies was determined. The mineral composition was compared with the magnetic properties of rocks, such as inductive and remanent magnetization, Curie temperature, anisotropy of magnetic susceptibility, and the Koenigsberg factor. The influence of the mineral composition on the magnetic properties of rocks is considered. This, in turn, will further increase the reliability of the interpretation of the results of tectonomagnetic monitoring performed here.
Assessment of the ecological state of the composition of surface waters and bottom sediments in the Yamalo-Nenets Autonomous Okrug
Authors: Starostin S. A. , Yurkevich N. V. , Edelev A. V. , Kolesnikov R. A.
Published: October 2022

The article shows the results of analyzes of surface waters and bottom sediments of the Yamalo-Nenets Autonomous Okrug. The following rivers were selected as objects: the Ob, the Taz, the Pur, the Yuribei etc. Sampling was carried out near settlements Salekhard, Nadym, Salemal, Pitlyar etc. Water samples were analyzed for the content of: dissolved oxygen, chemical oxygen demand, concentrations of oil products, iron, copper, zinc, nickel, manganese, sulfate ions, bottom sediment samples - for pH values of water extract, content of oil products, sulfates, iron, nickel, chromium, manganese, copper, mercury, lead, zinc, cadmium. Excesses of concentrations of iron, manganese and copper (relative to standard values) were found in most water samples. Elevated levels of petroleum products, lead, chromium, zinc, nickel, iron, manganese and copper (compared to the approved background values) were detected in many bottom sediment samples.
Hubungan Pengetahuan tentang Covid-19 dengan Kepatuhan Protokol Kesehatan Mahasiswa
Authors: Christine Christine , Agustiany Dessy
Published: October 2022

Pendahuluan: Virus Corona atau Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) ialah virus yang menyerang sistem pernafasan manusia. Penyakit akibat infeksi virus ini disebut Covid-19. Tujuan: Penelitian ini bertujuan diketahuinya hubungan pengetahuan tentang Covid-19 dengan kepatuhan protokol kesehatan pada mahasiswa. Metode: Penelitian ini merupakan jenis penelitian Cross Sectional. Populasi penelitian ini adalah mahasiswa prodi D-III Sanitasi poltekkes Kemenkes Palu. Teknik pengambilan sampel adalah stratified random sampling dihitung dengan menggunakan rumus Lemeshow. Cara pengambilan sampel menggunakan rumus estimasi proporsi dengan besar sampel sebanyak 100 orang. Uji korelasi Spearman dilakukan untuk menganalisis hubungan pengetahuan tentang Covid-19 dan kepatuhan terhadap protokol kesehatan. pada mahasiswa Prodi D-III Sanitasi Poltekkes Kemenkes Palu. Hasil: Uji korelasi Spearman untuk menganalisis hubungan pengetahuan tentang Covid-19 dan kepatuhan terhadap protokol kesehatan pada mahasiswa Prodi D-III Sanitasi Poltekkes Kemenkes Palu menghasilkan nilai p=0,08. Kesimpulan: Tidak ada hubungan antara pengetahuan tentang Covid-19 dengan kepatuhan protokol kesehatan pada mahasiswa Prodi D-III Sanitasi Poltekkes Kemenkes Palu.
Clinical viability of magnetic bead implants in muscle
Authors: Taylor Cameron R. , Clark William H. , Clarrissimeaux Ellen G. , Yeon Seong Ho , Carty Matthew J. , Lipsitz Stuart R. , Bronson Roderick T. , Roberts Thomas J. , Herr Hugh M.
Published: October 2022

Human movement is accomplished through muscle contraction, yet there does not exist a portable system capable of monitoring muscle length changes in real time. To address this limitation, we previously introduced magnetomicrometry, a minimally-invasive tracking technique comprising two implanted magnetic beads in muscle and a magnetic field sensor array positioned on the body’s surface adjacent the implanted beads. The implant system comprises a pair of spherical magnetic beads, each with a first coating of nickel-copper-nickel and an outer coating of Parylene C. In parallel work, we demonstrate submillimeter accuracy of magnetic bead tracking for muscle contractions in an untethered freely-roaming avian model. Here, we address the clinical viability of magnetomicrometry. Using a specialized device to insert magnetic beads into muscle in avian and lagomorph models, we collect data to assess gait metrics, bead migration, and bead biocompatibility. For these animal models, we find no gait differences post-versus pre-implantation, and bead migration towards one another within muscle does not occur for initial bead separation distances greater than 3 cm. Further, using extensive biocompatibility testing, the implants are shown to be non-irritant, non-cytotoxic, non-allergenic, and non-irritating. Our cumulative results lend support for the viability of these magnetic bead implants for implantation in human muscle. We thus anticipate their imminent use in human-machine interfaces, such as in control of prostheses and exoskeletons and in closed-loop neuroprosthetics to aid recovery from neurological disorders.
Novel bio-catalytic degradation of endocrine disrupting compounds in wastewater
Authors: P Budeli , JO Unoufin , Moropeng Resoketswe Charlotte , Momba MNB
Published: October 2022

Against the backdrop of towering ecological health implications of estrogen pollution and the inefficacies associated with cost-intensive treatment techniques, this study recorded the earliest attempt of developing an inexpensive bacterial laccase-based biocatalysts for biodegradation of EDCs (Endocrine disrupting compounds), particularly estrogens. First, a central composite design was used to investigate the interactive effects of pH (6.0–8.0), inoculum size (100–500 U/mL), and copper (Cu) (25–75 mg/L) on laccase activity and estrogen degradation respectively. Thereafter, biocatalysts was synthesized comprising laccase and glass beads or silver impregnated clay granules (SICG), which was further used to treat estrogen infused aquatic matrices under different reaction conditions. Maximum laccase activities and estrogen removal for the two tested laccases were 620 U/mL (85.8–92.9%) and 689.8 U/mL (86.8–94.6%) for Lysinibacillus sp. BP1 and Lysinibacillus sp. BP2, respectively, within 72 h, under conditions of optimal inoculum size and/or Cu concentration. Apart from a higher estrogen removal rate compared to free laccased, the biocatalysts were more resistant to temperature, pH and other environmental perturbations, and had enhanced storage ability and reusability. In comparison to clay, beads had a higher potential for recyclability and were more stable under certain experimental factors such as pH, reuse, and temperature, as well as storage conditions. Immobilized enzymes were able to remove 100% of E2, as well as over 90% of E1 and EE2, in 24 h, indicating that they could be scaled up to benchtop bioreactor levels.
Initial characterization of gap phase introduction in every cell cycle of C. elegans embryogenesis
Authors: Wong Ming-Kin , Ho Vincy Wing Sze , Huang Xiaotai , Chan Lu-Yan , Xie Dongying , Li Runsheng , Ren Xiaoliang , Guan Guoye , Ma Yiming , Hu Boyi , Yan Hong , Zhao Zhongying
Published: October 2022

Early embryonic cell cycles usually alternate between S and M phases without any gap phase. When the gap phases are developmentally introduced in various cell types remains poorly defined especially during embryogenesis. To establish the cell-specific introduction of gap phases in embryo, we generate multiple fluorescence ubiquitin cell cycle indicators (FUCCI) in C. elegans. Time-lapse 3D imaging followed by lineal expression profiling reveals sharp and differential accumulation of the FUCCI reporters, allowing the systematic demarcation of cell cycle phases throughout embryogenesis. Accumulation of the reporters reliably identifies both G1 and G2 phases only in two embryonic cells with an extended cell cycle length, suggesting that the remaining cells divide either without a G1 phase, or with a brief G1 phase that is too short to be picked up by our reporters. In summary, we provide an initial picture of gap phase introduction in a metazoan embryo. The newly developed FUCCI reporters pave the way for further characterization of developmental control of cell cycle progression.
Cobalt chloride has beneficial effects across species through a hormetic mechanism
Authors: Schiavi Alfonso , Runci Alessandra , Maiorino Teresa , Naso Francesco Davide , Barenys Marta , Fritsche Ellen , Strappazzon Flavie , Ventura Natascia
Published: October 2022

Severe oxygen and iron deficiencies have evolutionarily conserved detrimental effects, leading to pathologies in mammals and developmental arrest as well as neuromuscular degeneration in the nematode Caenorhabditis elegans. Yet, similar to the beneficial effects of mild hypoxia, non-toxic levels of iron depletion, achieved with the iron chelator bipyridine or through frataxin silencing, extend C. elegans lifespan through hypoxia-like induction of mitophagy. While the positive health outcomes of hypoxia preconditioning are evident, its practical application is rather challenging. Here, we thus test the potential beneficial effects of non-toxic, preconditioning interventions acting on iron instead of oxygen availability. We find that limiting iron availability through the iron competing agent cobalt chloride has evolutionarily conserved dose-dependent beneficial effects: while high doses of cobalt chloride have toxic effects in mammalian cells, iPS-derived neurospheres, and in C. elegans, sub-lethal doses protect against hypoxia- or cobalt chloride-induced death in mammalian cells and extend lifespan and delay age-associated neuromuscular alterations in C. elegans. The beneficial effects of cobalt chloride are accompanied by the activation of protective mitochondrial stress response pathways.
Dynamic simulation of a compact sorption-enhanced water-gas shift reactor
Authors: Stadler Tabea J. , Bender Laila J. , Pfeifer Peter
Published: October 2022

This work presents the dynamic simulation of a novel sorption-enhanced water-gas shift reactor used for synthesis gas production from pure CO in an e-fuels synthesis process. Due to the intended decentralized plant installation associated with fluctuating feed, process intensification and a compact reactor system is required. An optimized operating procedure was obtained by simulation-driven process design to maximize the sorbent loading and operate the process as efficient as possible. The process simulation is based on a simplified heterogeneous packed bed reactor model. The model accounts for simultaneous water-gas shift (WGS) reaction on a Cu-based catalyst and CO2 adsorption on a K-impregnated hydrotalcite-derived mixed oxide as well as subsequent desorption. An empirical rate expression was chosen to describe the water-gas shift reaction according to experimental data at 250°C. Breakthrough experiments were performed and used to adapt kinetic adsorption (pressure: 8 bar) and desorption (pressure: 1 bar) parameters. The experimental CO2 sorption equilibrium isotherm was fitted with the Freundlich model. The reactor model was extended to a complex hybrid system scale model for the pilot plant reactor consisting of six individually accessible reaction chambers. Cyclic operation with automatized switching time adjustment was accomplished by a finite state machine. A case study exploited the benefits of a serial process configuration of reaction chambers. It could be shown that the sorbent loading can be remarkably increased through optimized operating strategies depending on the process conditions. Hence, the development of the hybrid model marks a crucial step towards the planned pilot plant operation and control.
Chemodivergent photocatalytic access to 1-pyrrolines and 1-tetralones involving switchable C(sp3)–H functionalization
Authors: Tu Shijing , Qi Zhongyu , Li Weicai , Zhang Shiqi , Zhang Zhijie , Wei Jun , Yang Lin , Wei Siping , Du Xi , Yi Dong
Published: October 2022

A chemodivergent photocatalytic approach to 1-pyrrolines and 1-tetralones from alkyl bromides and vinyl azides has been developed through chemoselectively controllable intermolecular [3 + 2] and [4 + 2] cyclization. This photoredox-neutral two-component protocol involves intermolecular radical addition and switchable distal C(sp3)–H functionalization enabled by iminyl radical-mediated 1,5-hydrogen atom transfer. Meanwhile, chemoselectivity between C(sp3)–N bond formation and C(sp3)–C(sp2) bond formation is precisely switched by photocatalysts (Ru(bpy)3(PF6)2 vs. fac-Ir(ppy)3) and additives (base vs. acid).
Riluzole use in presence of contraindications in adults affected by amyotrophic lateral sclerosis and its off-label use in other motor neuron diseases: Findings from an Italian multicentre study (the CAESAR project)
Authors: Crescioli Giada , Finocchietti Marco , Cascini Silvia , Paoletti Olga , Franchini David , Cappello Emiliano , Valdiserra Giulia , Sciancalepore Francesco , Celani Maria Grazia , Tuccori Marco , Vannacci Alfredo , Lombardi Niccolò , Kirchmayer Ursula ,   the CAESAR Study Group
Published: October 2022

Background: This analysis describes the use of riluzole in amyotrophic lateral sclerosis (ALS) individuals with contraindications and off-label use for subjects with other motor neuron diseases (o-MND) in the Italian regions of Latium, Tuscany and Umbria.

Methods: A cohort of adults with ALS prescribed with riluzole during the years 2016–2019 was enrolled from administrative healthcare databases, excluding subjects with o-MND in the preceding 5 years. Being affected by ALS for more than 5 years, presence of tracheostomy, renal or hepatic failure were considered as contraindications to the use of riluzole. A cohort of adults with o-MND was enrolled in 2016–2019 for whom off-label use of riluzole was retrieved up to 4 years, analysing over the time differences related to sex.

Results: Among 206 ALS individuals prescribed with riluzole in Latium, 336 in Tuscany and 60 in Umbria, less than 1% were diagnosed with ALS for more than 5 years. Less than 2% were tracheotomised or affected by hepatic failure. Renal failure was documented for 1.9%, 2.7%, and 5.0% of ALS individuals in Latium, Tuscany and Umbria. The o-MND cohort comprised 264 subjects in Latium, 222 in Tuscany, and 66 in Umbria. Non-negligible off-label riluzole use was observed: 8.5%, 33.0%, and 4.2% in females, and 19.9%, 26.5% and 2.4% in males in Latium, Tuscany and Umbria.

Discussion: Riluzole use in ALS individuals in the presence of contraindications is rare, with slightly higher numbers in presence of renal failure. Off-label use in o-MND was found to be non-negligible, with variations between sexes.
Biogeochemistry and timing of methane-derived carbonate formation at Leirdjupet fault complex, SW Barents sea
Authors: Argentino Claudio , Lee Amicia , Fallati Luca , Sahy Diana , Birgel Daniel , Peckmann Jörn , Bünz Stefan , Panieri Giuliana
Published: October 2022

The origin of modern seafloor methane emissions in the Barents Sea is tightly connected to the glacio-tectonic and oceanographic transformations following the last ice age. Those regional events induced geological structure re-activation and destabilization of gas hydrate reservoirs over large areas of the European continental margins, sustaining widespread fluid plumbing systems. Despite the increasing number of new active seep discoveries, their accurate geochronology and paleo-dynamic is still poorly resolved, thus hindering precise identification of triggering factors and mechanisms controlling past and future seafloor emissions. Here, we report the distribution, petrographic (thin section, electron backscatter diffraction), isotopic (δ13C, δ18O) and lipid biomarker composition of methane-derived carbonates collected from Leirdjupet Fault Complex, SW Barents Sea, at 300 m depth during an ROV survey in 2021. Carbonates are located inside a 120 x 220 m elongated pockmark and form <10 m2 bodies protruding for about 2 m above the adjacent seafloor. Microstructural analyses of vein-filling cements showed the occurrence of three–five generations of isopachous aragonitic cement separated by dissolution surfaces indicative of intermittent oxidizing conditions. The integration of phase-specific isotopic analysis and U/Th dating showed δ13C values between −28.6‰ to −10.1‰ and δ18O between 4.6‰ and 5.3‰, enabling us to track carbonate mineral precipitation over the last ∼8 ka. Lipid biomarkers and their compound-specific δ13C analysis in the bulk carbonate revealed the presence of anaerobic methanotrophic archaea of the ANME-2 clade associated with sulfate-reducing bacteria of the Seep-SRB1 clade, as well as traces of petroleum. Our results indicate that methane and petroleum seepage in this area followed a similar evolution as in other southernmost Barents Sea sites controlled by the asynchronous deglaciation of the Barents Sea shelf, and that methane-derived carbonate precipitation is still an active process at many Arctic locations.
Conceptualizing and measuring instructional quality in mathematics education: A systematic literature review
Authors: Mu Jin , Bayrak Aslihan , Ufer Stefan
Published: October 2022

Conceptualizing and measuring instructional quality is important to understand what can be understood as “good teaching” and develop approaches to improve instruction. There is a consensus in teaching effectiveness research that instructional quality should be considered multidimensional with at least three basic dimensions rather than a unitary construct: student support, cognitive activation, and classroom management. Many studies have used this or similar frameworks as a foundation for empirical research. The purpose of this paper is to investigate the relation between the conceptual indicators underlying the conceptual definitions of the quality dimensions in the literature, and the various operational indicators used to operationalize these factors in empirical studies. We examined (a) which conceptual indicators are used to conceptualize the basic dimensions theoretically, (b) to which extent the operational indicator in the literature cover these conceptual indicators, and (c) if which additional indicators are addressed by the measurement instruments, which are not part of the theoretical conceptualization. We conducted a systematic literature review on the conceptualization and operationalization of Instructional Quality in Primary and Secondary Mathematics Education based on PRISMA procedures. We describe the span of conceptual indicators connected to the three basic dimensions over all articles (a) and analyze to which extent the measurement instruments are in line with these conceptual indicators (b, c). For each measurement dimension, the identified quality dimensions identified are, taken together, largely representative of the conceptual indicators connected to the core factor, but also a number of critical misconceptions occurred. Our review provides a comprehensive overview of the three basic dimensions of instructional quality in mathematics based on theoretical conceptualizations and measurement instruments in the literature. Beyond this, we observed that the descriptions of a substantial amount of quality dimensions and their conceptualizations did not clearly specify if the intended measurement referred to the learning opportunities orchestrated by the teacher, or the utilization of these opportunities by students. It remains a challenge to differentiate measures of instructional quality (as orchestrated by the teacher) from (perceived) teacher competencies/knowledge, and students’ reactions to the instruction. Recommendations are made for measurement practice, as well as directions for future research.
Lipid droplet - mitochondria coupling: A novel lipid metabolism regulatory hub in diabetic nephropathy
Authors: Yang Ming , Luo Shilu , Yang Jinfei , Chen Wei , He Liyu , Liu Di , Zhao Li , Wang Xi
Published: October 2022

Diabetic nephropathy (DN) involves serious lipid metabolism disorder, and renal ectopic lipid deposition aggravates DN progression. However, the molecular mechanism of renal lipid deposition in DN remains unclear. Lipid droplets (LDs) are lipid pools in cells that change dynamically in response to the cellular energy needs. The LDs and mitochondria are connected through a part of the mitochondria known as the peridroplet mitochondria (PDM). In this review, we summarize the definition, detection methods, and function of the PDM. Finally, we discuss the research status of PDM in DN and the possibility of its use as a therapeutic target.