bluuebunny/crossref_metadata_2025 huggingface dataset:
Fractional order generalized thermoelastic response in a half space due to a periodically varying heat source
Authors: Tripathi Jitesh , Warbhe Shrikant , Deshmukh K.C. , Verma Jyoti
Published: December 2017

Purpose

The present work is concerned with the solution of a fractional-order thermoelastic problem of a two-dimensional infinite half space under axisymmetric distributions in which lower surface is traction free and subjected to a periodically varying heat source. The thermoelastic displacement, stresses and temperature are determined within the context of fractional-order thermoelastic theory. To observe the variations of displacement, temperature and stress inside the half space, the authors compute the numerical values of the field variables for copper material by utilizing Gaver-Stehfast algorithm for numerical inversion of Laplace transform. The effects of fractional-order parameter on the variations of field variables inside the medium are analyzed graphically. The paper aims to discuss these issues.

Design/methodology/approach

Integral transform technique and Gaver-Stehfast algorithm are applied to prepare the mathematical model by considering the periodically varying heat source in cylindrical co-ordinates.

Findings

This paper studies a problem on thermoelastic interactions in an isotropic and homogeneous elastic medium under fractional-order theory of thermoelasticity proposed by Sherief (Ezzat and El-Karamany, 2011b). The analytic solutions are found in Laplace transform domain. Gaver-Stehfast algorithm (Ezzat and El-Karamany, 2011d; Ezzat, 2012; Ezzat, El Karamany, Ezzat, 2012) is used for numerical inversion of the Laplace transform. All the integrals were evaluated using Romberg’s integration technique (El-Karamany et al., 2011) with variable step size. A mathematical model is prepared for copper material and the results are presented graphically with the discussion on the effects of fractional-order parameter.

Research limitations/implications

Constructed purely on theoretical mathematical model by considering different parameters and the functions.

Practical implications

The system of equations in this paper may prove to be useful in studying the thermal characteristics of various bodies in real-life engineering problems by considering the time fractional derivative in the field equations.

Originality/value

In this problem, the authors have used the time fractional-order theory of thermoelasticity to solve the problem for a half space with a periodically varying heat source to control the speed of wave propagation in terms of heat and elastic waves for different conductivity like weak conductivity, moderate conductivity and super conductivity which is a new and novel contribution.
The Curtin Materials Availability Survey 2017
Authors: Wells David
Published: December 2017

Purpose

The purpose of this paper is to extend the principles of earlier print-based availability surveys to the context of today’s electronic library, and explores the question of an appropriate methodology. The ability of clients to find what they want remains a central question, as does the library’s ability to identify and address the reasons that clients fail to find what they are looking for.

Design/methodology/approach

Catalogue users at Curtin University Library were invited to complete an online survey indicating whether they had found the electronic item they were looking for, and if not to nominate the reason why. Responses were then verified and analysed by library staff.

Findings

The survey attracted a low number of usable responses, though the proportion of respondents who stated they were able to find what they were looking for was consistent with the findings of earlier studies. It was possible to identify a small number of cases where the library did not hold the item required, though most failures were either due to technical reasons or could not be fully investigated because not enough information was provided by the respondent.

Research limitations/implications

The survey conducted was inconclusive, partly because the delivery method used was quite cumbersome, and also because it focussed on known item searches rather than topic searches. The paper includes suggestions on how the survey could be broadened and technically improved.

Originality/value

The paper shows the value and limitations of conducting a materials availability survey in the electronic library, and makes suggestions on how the effectiveness of such a survey can be maximised.
Introduction: Labour migration in Europe: Changing policies – changing organizations – changing people
Authors: Laubenthal Barbara
Published: December 2017

Under which circumstances do labour migration policies change? When do organizations become agents of change? And what triggers significant transformation in labour migration flows? We start from the assumption that, during the last years, change in the field of labour migration has intensified. In some countries, paradigmatic changes towards more liberal immigration regimes have taken place; new organizations have emerged; and the profile of intra‐European workers’ mobility has changed. The articles assembled in this volume shed light on developments in the field of labour migration by using the notion of change as their conceptual lens. They show that changes can best be captured with a multi‐level model and an interdisciplinary approach that connects labour migration issues to broader political science and sociological theories. Such an analysis shows that recent changes are paradigmatic, multi‐layered and ambiguous with regard to a further liberalization of the European labour migration regime.
Uptake kinetics and storage capacity of dissolved inorganic phosphorus and corresponding N:P dynamics in Ulva lactuca (Chlorophyta)
Authors: Lubsch Alexander , Timmermans Klaas
Published: December 2017

Dissolved inorganic phosphorus (DIP) is an essential macronutrient for maintaining metabolism and growth in autotrophs. Little is known about DIP uptake kinetics and internal P‐storage capacity in seaweeds, such as Ulva lactuca (Chlorophyta). Ulva lactuca is a promising candidate for biofiltration purposes and mass commercial cultivation. We exposed U. lactuca to a wide range of DIP concentrations (1–50 μmol · L−1) and a nonlimiting concentration of dissolved inorganic nitrogen (DIN; 5,000 μmol · L−1) under fully controlled laboratory conditions in a “pulse‐and‐chase” assay over 10 d. Uptake kinetics were standardized per surface area of U. lactuca fronds. Two phases of responses to DIP‐pulses were measured: (i) a surge uptake (VS) of 0.67 ± 0.10 μmol · cm−2 · d−1 and (ii) a steady state uptake (VM) of 0.07 ± 0.03 μmol · cm−2 · d−1. Mean internal storage capacity (ISCP) of 0.73 ± 0.13 μmol · cm−2 was calculated for DIP. DIP uptake did not affect DIN uptake. Parameters of DIN uptake were also calculated: VS = 12.54 ± 1.90 μmol · cm−2 · d−1, VM = 2.26 ± 0.86 μmol · cm−2 · d−1, and ISCN = 22.90 ± 6.99 μmol · cm−2. Combining ISC and VM values of P and N, nutrient storage capacity of U. lactuca was estimated to be sufficient for ~10 d. Both P and N storage capacities were filled within 2 d when exposed to saturating nutrient concentrations, and uptake rates declined thereafter at 90% for DIP and at 80% for DIN. Our results contribute to understanding the ecological aspects of nutrient uptake kinetics in U. lactuca and quantitatively evaluating its potential for bioremediation and/or biomass production for food, feed, and energy.
Molecular classification of autofluorescence excision margins in oral potentially malignant disorders
Authors: Farah C S , Kordbacheh F , John K , Bennett N , Fox S A
Published: December 2017

Objective

To define molecular differences between autofluorescence and white light defined excision margins in oral potentially malignant disorders (OPMD) using transcriptome expression profiles.

Materials and methods

Excisional biopsy specimens were taken from 11 patients at three different sites for each lesion: centre, white light margin and autofluorescence margin. The lesions were diagnosed histopathologically as oral epithelial dysplasia, oral lichenoid dysplasia, oral lichen planus or other. Transcriptome analysis was performed by RNA sequencing, hierarchical clustering, differential expression and biological pathway analysis.

Results

For hierarchical clustering, the samples broadly clustered according to histology rather than the margins with lichenoid samples clustering together. Differential expression analysis showed that independent of histology, there was greater molecular dysregulation between the lesion centre and autofluorescence margin compared to the lesion centre and white light margin. Furthermore, the autofluorescence and white light margins were molecularly distinct, indicating the white light margins harboured abnormality.

Conclusion

Our results indicate that the molecular profile of OPMD changes with divergence away from the centre of the lesion, and that autofluorescence determined margins are superior to the white light margin in achieving a clear molecular margin when excising an OPMD.
¿Agua sí, oro no? Anclajes del extractivismo y el ambientalismo en el páramo de Santurbán
Authors: Osejo Alejandra , Ungar Paula
Published: December 2017

En los últimos años, los páramos han adquirido protagonismo en el escenario público colombiano como territorios disputados entre diferentes intereses, visiblemente entre aquellos alineados en torno al cuidado del agua y los vinculados al extractivismo minero. A través de un estudio de caso en el páramo de Santurbán, una zona clave para la provisión de agua para más de un millón de habitantes urbanos y rurales de sus alrededores, que alberga importantes reservas de oro y actividad agrícola intensiva, este trabajo aporta a la comprensión de los páramos como territorios cuyas transformaciones resultan de complejas interacciones históricas e interescalares, visibles tanto en torno al extractivismo como al ambientalismo. Apoyándonos en una perspectiva relacional y en el concepto de fricción propuesto por Anna Tsing, pretendemos aportar a la comprensión de esta complejidad y llamar la atención sobre la necesidad de tener en cuenta la multiescalaridad en las políticas de Estado con objetivos conservacionistas.
Empresas, recursos económicos y gobiernos indígenas: una aproximación al estudio de las redes clientelares en un resguardo indígena en la Altillanura colombiana
Authors: Calle Alzate Laura
Published: December 2017

A partir de los datos construidos como resultado de mi trabajo de campo etnográfico en el Resguardo Wacoyo, este artículo pretende ilustrar algunos de los efectos de la presencia de empresas nacionales e internacionales, dedicadas a la extracción de materias primas y la agroindustria, sobre las relaciones políticas internas del Resguardo. La presencia de estas empresas ha tenido impactos significativos en las dinámicas políticas internas de los pueblos indígenas asentados en el municipio, debilitando y fragmentando a las comunidades y sus gobiernos. En particular, argumentaré que estos recursos se han convertido en la nueva base económica que alimenta las redes clientelares comunitarias indígenas, y en la causa de tensiones y disputas políticas entre líderes y comuneros indígenas. Empezaré por describir cómo se impuso un nuevo modelo de desarrollo en la región, para luego explicar el funcionamiento de las redes clientelares a nivel regional y comunitario.
Ecoturismo, gubernamentalidad neoliberal y despojos en la Amazonia colombiana
Authors: Montenegro Perini Iván Emilio
Published: December 2017

Este artículo analiza hasta qué punto los campesinos de una zona del departamento del Guaviare (Amazonia colombiana) fueron sujetados por los principios del ecoturismo neoliberal, y examina los efectos sociopolíticos asociados a la disposición de los conocimientos ambientales-empresariales en sus vidas. Exploro las adaptaciones y límites de la medioambientalidad neoliberal, en el marco del ecoturismo, y los efectos socioecológicos de sus tecnologías de gobierno sobre poblaciones campesinas. Me concentro particularmente en cómo estas tecnologías se adaptan a intereses de grupos particulares de la región, y en cómo, a través de diversos mecanismos i/legales, el ecoturismo se vuelve funcional a estrategias sofisticadas de despojo que los campesinos deben sortear. Por un lado, examino los despojos en nombre de la conservación a través de la culpabilización de los campesinos, y, por el otro, abordo la configuración de otras modalidades de despojo más sutiles que he llamado despojos político-ontológicos.
A Phenomenological Model for Turbulent Heat Flux in High-Speed Flows With Shock-Induced Flow Separation
Authors: Pathak Utkarsh , Roy Subhajit , Sinha Krishnendu
Published: December 2017

High-speed flows with shock waves impinging on turbulent boundary layers pose severe challenge to current computational methods and models. Specifically, the peak wall heat flux is grossly overpredicted by Reynolds-averaged Navier–Stokes (RANS) simulations using conventional turbulence models. This is because of the constant Prandtl number assumption, which fails in the presence of strong adverse pressure gradient (APG) of the shock waves. Experimental data suggest a reduction of the turbulent Prandtl number in boundary layers subjected to APG. We use a phenomenological approach to develop an algebraic model based on the available data and cast it in a form that can be used in high-speed flows with shock-induced flow separation. The shock-unsteadiness (SU) k–ω model is used as the baseline, since it gives good prediction of flow separation and the regions of APG. The new model gives marked improvement in the peak heat flux prediction near the reattachment point. The formulation is applicable to both attached and separated flows. Additionally, the simplicity of the formulation makes it easily implementable in existing numerical codes.
Rayleigh scattering of a cylindrical sound wave by an infinite cylinder
Authors: Baynes Alexander B. , Godin Oleg A.
Published: December 2017

Rayleigh scattering, in which the wavelength is large compared to the scattering object, is usually studied assuming plane incident waves. However, full Green's functions are required in a number of problems, e.g., when a scatterer is located close to the ocean surface or the seafloor. This paper considers the Green's function of the two-dimensional problem that corresponds to scattering of a cylindrical wave by an infinite cylinder embedded in a homogeneous fluid. Soft, hard, and impedance cylinders are considered. Exact solutions of the problem involve infinite series of products of Bessel functions. Here, simple, closed-form asymptotic solutions are derived, which are valid for arbitrary source and receiver locations outside the cylinder as long as its diameter is small relative to the wavelength. The scattered wave is given by the sum of fields of three linear image sources. The viability of the image source method was anticipated from known solutions of classical electrostatic problems involving a conducting cylinder. The asymptotic acoustic Green's functions are employed to investigate reception of low-frequency sound by sensors mounted on cylindrical bodies.
Intravenous versus oral paracetamol for acute pain in adults in the emergency department setting: a prospective, double-blind, double-dummy, randomised controlled trial
Authors: Furyk Jeremy , Levas Deahnne , Close Benjamin , Laspina Kathryn , Fitzpatrick Meghan , Robinson Kelvin , Vangaveti Venkat N , Ray Robin
Published: December 2017

Objective

To determine if intravenous paracetamol was superior to oral paracetamol as an adjunct to opioids in the management of moderate to severe pain in the ED setting.

Methods

A prospective, randomised, double-blind, double-dummy, controlled trial was conducted at a single academic tertiary care ED. Adult patients with moderate to severe pain were randomly assigned to receive either the intravenous paracetamol or oral paracetamol. The primary outcome was Visual Analogue Scale (VAS) pain reduction at 30 min. A clinically significant change in pain was defined as 13 mm.

Results

87 participants were included in the final analysis, with a median age of 43.5 years and 59.8% were female. Overall mean baseline VAS pain score was 67.9 mm (±16.0). Both formulations achieved a clinically significant mean pain score reduction at 30 min, with no significant difference between the groups with 16.0 mm (SD 19.1 mm) in the intravenous group and 14.6 mm (SD 26.4) in the oral group; difference −1.4 mm (95% CI −11.6 to 8.8, P=0.79). Secondary outcomes, including postintervention intravenous opioid administration, patient satisfaction, side effects and length of stay, did not differ between groups.

Conclusions

Overall, there was a small but clinically significant decrease in pain in each group. No superiority was demonstrated in this trial with intravenous paracetamol compared with oral paracetamol in terms of efficacy of analgesia and no difference in length of stay, patient satisfaction, need for rescue analgesia or side effects.
Sebaceous tumours: more than skin deep
Authors: Jockenhöfer Finja , Schimming Tobias T , Schaller Jörg , Moege Jürgen , Livingstone Elisabeth , Salva Katrin A , Zimmer Lisa , Schadendorf Dirk , Rösch Alexander
Published: December 2017

Clinical presentation

A 77-year-old man presented to our skin cancer centre with various cutaneous tumours occurring in 2006–2017. Histopathology showed a ‘hidradenocarcinoma’ on the left upper back (2006) and a sebaceous adenoma (figure 1) on the left shoulder (2011). In 2017, he developed a sebaceous carcinoma on the middle upper back, which manifested as a slowly enlarging, asymptomatic nodule. Medical history was significant for curative resection of colorectal cancer in 1988.

Figure 1

Clinical appearance of the sebaceous adenoma on the patient’s left shoulder in 2011.

The most recent lesion was subjected to extensive immunohistochemical assessment. The neoplastic cells were positive for cytokeratin 5/6, cytokeratin 7, cluster of differentiation antigen 10, adipophilin, androgen receptor, epithelial membrane antigen, KI67 antigen, MLH1 and PMS2, but stained negative for gross cystic disease fluid protein 15, prostate-specific antigen, carbohydrate antigen 19/9, CDX2 protein, hepatocyte-specific antigen, carcinoembryonic antigen, cluster of differentiation antigen 117 and cytokeratin 19. Given the variety of histological manifestations of the patient’s skin neoplasms, further studies were performed. They revealed positive nuclear expression signals for MLH1, MSH6 and PMS2, whereas MSH2 expression was absent in almost all tumour cells (figure 2). Positron emission tomography (PET)/CT and colonoscopy did not detect any pathological findings. However, molecular genetic analysis of peripheral blood showed a heterozygous deletion of exon 7 of the MSH2 gene. Subsequently, several family members tested positive for MSH2 mutations and underwent genetic counselling.

Figure 2

(A–D) Histopathological images of the patient’s most recent lesion (diaminobenzidine, original magnification, ×100). The tumour cells demonstrated strong nuclear positivity for MLH1 (A) and PMS2 (B), but were essentially negative for MSH6 (C) and MSH2 (D).

Question

What is your diagnosis?

Diagnosis: Muir-Torre syndrome (MTS).
Fourier transform of hydrogen-type atomic orbitals
Authors: Yükçü N. , Yükçü S.A.
Published: December 2017

Hydrogen-type atomic orbitals (HTOs) are an important type of exponential-type orbital. These orbitals have some mathematical properties and they are used usually in the theoretical atomic and molecular investigations as special functions to figure out analytical expressions. The Fourier transform method is a great way to convert basis functions into the momentum space, because their Fourier transforms are easier to use in mathematical calculations. In this paper, we obtain new and useful mathematical representations for the Fourier transform of HTOs related with Gegenbauer polynomials and hypergeometric functions, by using recurrence relations of Laguerre polynomials, Rayleigh expansion and some properties of normalized HTOs.
The Degree of Irreversibility in Deterministic Finite Automata
Authors: Axelsen Holger Bock , Holzer Markus , Kutrib Martin
Published: December 2017

Recently, a method to decide the NL-complete problem of whether the language accepted by a given deterministic finite automaton (DFA) can also be accepted by some reversible deterministic finite automaton (REV-DFA) has been derived. Here, we show that the corresponding problem for nondeterministic finite automata (NFA) is PSPACE-complete. The recent DFA method essentially works by minimizing the DFA and inspecting it for a forbidden pattern. We here study the degree of irreversibility for a regular language, the minimal number of such forbidden patterns necessary in any DFA accepting the language, and show that the degree induces a strict infinite hierarchy of language families. We examine how the degree of irreversibility behaves under the usual language operations union, intersection, complement, concatenation, and Kleene star, showing tight bounds (some asymptotically) on the degree.
Complexity of Matching Sets of Two-Dimensional Patterns by Two-Dimensional On-Line Tessellation Automaton
Authors: Průša Daniel
Published: December 2017

We study the two-dimensional pattern matching implemented using the deterministic two-dimensional on-line tessellation automaton. This restricted two-dimensional cellular automaton is able to simulate the Baker–Bird algorithm, which was proposed as the first algorithm for the two-dimensional pattern matching. We explore capabilities of this automaton to carry out the matching task against an arbitrary set of equal-sized patterns. To measure amount of resources needed to accomplish it, we introduce the pattern complexity of a picture language. We show that this complexity ranges from a constant to exponential one. All of these are illustrated by giving examples of two-dimensional on-line tessellation automata matching sets of patterns, describing general techniques of how to construct them and proving lower bounds on the pattern complexity of some picture languages as well as operations over them.
Propagation of chaos for aggregation equations with no-flux boundary conditions and sharp sensing zones
Authors: Choi Young-Pil , Salem Samir
Published: December 2017

We consider an interacting [Formula: see text]-particle system with the vision geometrical constraints and reflected noises, proposed as a model for collective behavior of individuals. We rigorously derive a continuity-type of mean-field equation with discontinuous kernels and the normal reflecting boundary conditions from that stochastic particle system as the number of particles [Formula: see text] goes to infinity. More precisely, we provide a quantitative estimate of the convergence in law of the empirical measure associated to the particle system to a probability measure which possesses a density which is a weak solution to the continuity equation. This extends previous results on an interacting particle system with bounded and Lipschitz continuous drift terms and normal reflecting boundary conditions by Sznitman [J. Funct. Anal. 56 (1984) 311–336] to that one with discontinuous kernels.
Context Weighting for Ubiquitous Learning Situation Description: Approach Based on Combination of Weighted Experts’ Opinions
Authors: Souabni Raoudha , Saâdi Ines Bayoudh , Kinshuk  , Ghezala Henda Ben
Published: December 2017

Situation awareness is an emerging concept in ubiquitous environments, particularly the learning ones. Situation identification techniques developed in literature aim to infer the user’s situation from the detected context. Most of the studies to date in ubiquitous learning (u-learning) field give equal importance for detected context elements to describe learner’s situation and therefore allow irrelevant context elements to have as much effect on situation description as relevant ones. Therefore, different weights need to be associated to context elements with reference to their importance to the inference process. In this paper, a new proposal for weighting u-learning context elements is detailed. The solution aims to merge different expert opinions about context elements weighting for situation description. Evidence theory is applied in order to handle uncertain and conflicting expert opinions. Experimental results are given to illustrate the applicability of the proposed solution in selecting characteristic context elements appropriate for each u-learning situation pattern and distinguishing them from others.
Proteomic Mapping of Dental Enamel Matrix from Inbred Mouse Strains: Unraveling Potential New Players in Enamel
Authors: Lima Leite Aline , Silva Fernandes Mileni , Charone Senda , Whitford Gary Milton , Everett Eric T. , Buzalaf Marília Afonso Rabelo
Published: December 2017

Enamel formation is a complex 2-step process by which proteins are secreted to form an extracellular matrix, followed by massive protein degradation and subsequent mineralization. Excessive systemic exposure to fluoride can disrupt this process and lead to a condition known as dental fluorosis. The genetic background influences the responses of mineralized tissues to fluoride, such as dental fluorosis, observed in A/J and 129P3/J mice. The aim of the present study was to map the protein profile of enamel matrix from A/J and 129P3/J strains. Enamel matrix samples were obtained from A/J and 129P3/J mice and analyzed by 2-dimensional electrophoresis and liquid chromatography coupled with mass spectrometry. A total of 120 proteins were identified, and 7 of them were classified as putative uncharacterized proteins and analyzed in silico for structural and functional characterization. An interesting finding was the possibility of the uncharacterized sequence Q8BIS2 being an enzyme involved in the degradation of matrix proteins. Thus, the results provide a comprehensive view of the structure and function for putative uncharacterized proteins found in the enamel matrix that could help to elucidate the mechanisms involved in enamel biomineralization and genetic susceptibility to dental fluorosis.
The Challenging Acute Buried Bumper Syndrome: A Case Report
Authors: Pinho Juliana , Libânio Diogo , Pimentel-Nunes Pedro , Dinis-Ribeiro Mário
Published: December 2017

Percutaneous endoscopic gastrostomy (PEG) is the preferred route of feeding and nutritional support in patients requiring long-term enteral nutrition. Major complications related to the procedure are rare. Buried bumper syndrome is a late major complication, occurring in 0.3-2.4% of patients. Although considered a late complication, it can rarely occur in an acute setting early after the procedure. We present the case of an early buried bumper syndrome, presenting 1 week after PEG tube placement, with local stoma infection associated with an infected cavity within the abdominal wall with feeding content, successfully managed with antibiotic therapy and PEG tube repositioning through the original track.
Evaluation of Hair Density in Different Ethnicities in a Healthy American Population Using Quantitative Trichoscopic Analysis
Authors: Birnbaum Mathew R. , McLellan Beth N. , Shapiro Jerry , Ye Kenny , Reid Sophia D.
Published: December 2017

Background: There is limited research into normative hair density values in individuals of Hispanic descent. Methods: In order to help establish baseline density values in these individuals, we evaluated the hair density in 99 Americans of Hispanic descent and compared them with the values in 44 individuals of African descent and 23 Caucasians. Participants were recruited from a New York City medical center and self-identified their ethnicity. Biracial individuals were excluded from the study. Results: The hair density means ± SD ranged from 169 ± 31 to 178 ± 33/cm2 in Americans of Hispanic descent, from 148 ± 25 to 160 ± 27/cm2 in individuals of African descent, and from 214 ± 28 to 230 ± 33/cm2 in Caucasian individuals. All differences in hair densities between the ethnicities were statistically significant (p values ranging from 3.03 × 10-14 to 0.0249). Conclusion: While trichoscopy is not as accurate as invasive histological assessment of hair density or phototrichogram, it is still a reliable and fast method for assessing hair density. Increased awareness of ethnic variances in hair density can help clinicians and researchers diagnose hair disorders, monitor response to therapy, and conduct hair-related research in these patients.
Sesamin Protects Against Cardiac Remodeling Via Sirt3/ROS Pathway
Authors: Fan Di , Yang Zheng , Liu Fang-yuan , Jin Ya-Ge , Zhang Ning , Ni Jian , Yuan Yuan , Liao Hai-Han , Wu Qing-Qing , Xu Man , Deng Wei , Tang Qi-Zhu
Published: December 2017

Background/Aims: Cardiac remodeling is associated with oxidative stress. Sesamin, a well-known antioxidant from sesamin seeds, have been used extensively as traditional health foods. However, there is little known about the effect of sesamin on cardiac remodeling. Therefore, the present study aimed to determine whether sesamin could protect against cardiac remodeling and to clarify potential molecular mechanisms. Methods: The mice were subjected to either transverse aortic constriction (TAC) or sham surgery (control group). Beginning one week after surgery, the mice were oral gavage treated with sesamin (100mg·kg-1·day-1) or vehicle for 3 weeks. Cardiac hypertrophy was assessed by echocardiographic parameters, histological analyses and hypertrophic markers. Results: Sesamin alleviated cardiac hypertrophy, inhibited fibrosis and attenuated the inflammatory response. The increased production of reactive oxygen species, the activation of ERK1/2-dependent nuclear factor-κB and the increased level of Smad2 phosphorylation were observed in cardiac remolding model that were treated with sesamin. Furthermore, TAC induced alteration of Sirt3 and SOD2 was normalized by sesamin treatment. Finally, a selective Sirt3 inhibitor 3-TYP blocks all the protective role of sesamin, suggesting that a Sirt3-dependent effect of sesamin on cardiac remodeling. Conclusion: Sesamin improves cardiac function and prevents the development of cardiac hypertrophy via Sirt3/ROS pathway. Our results suggest the protective effect of sesamin on cardiac remolding.
Georges Canguilhem and psychiatry: norm, health and mental pathology
Authors: Franco Fábio Luís Ferreira Nóbrega
Published: December 2017

Para o epistemólogo e médico francês Georges Canguilhem existe uma diferença qualitativa entre a saúde e a doença. Segundo ele, os estados patológicos revelam uma estrutura individual modifi cada qualitativamente distinta do estado normal, cuja singularidade apenas pode ser apreciada na relação do organismo com o seu meio. A partir da proximidade entre a dimensão do orgânico e do psíquico em Canguilhem, o presente artigo objetiva analisar a concepção canguilhemeana de norma, saúde e patologia mental
Necessary propositions, grammatical propositions
Authors: Silva Giovane Rodrigues
Published: December 2017

Inicialmente, pretende-se apresentar o conceito de gramática nas Investigações Filosóficas de Wittgenstein, para em seguida examinar a função que as chamadas proposições gramaticais desempenham no que Wittgenstein chamou de determinação do sentido, em contraste com o emprego do sentido. Na medida em que este trabalho se insere num projeto sobre a arbitrariedade da gramática, esperamos apontar, à guisa de conclusão, para o fato de que aquilo que em geral a filosofia chama de proposição necessária é a mera expressão de uma regra gramatical que, entre outros elementos, compõe o ensino do uso de expressões da uma língua
The Whisper of an Elegy: musical sublime and the aesthetic-political gesture
Authors: Ferreira Rodney
Published: December 2017

Situando-se fundamentalmente em leituras de Rancière e Lyotard, este trabalho propõe-se avaliar, através da relação de conceitos como “sublime” e “estado estético” com a Música, a possibilidade de formação de uma sensibilidade política, e talvez mesmo de um sujeito político, a partir do desencanto e luto próprios ao contexto estético-político da modernidade. Ou seja, encontrar uma consciência referenciada à angústia das ruínas utópicas e formais cujo ato político não se refira à consciência social, e sim à noção de “gesto sublime”, em diálogo com a música, como acontecimento do indeterminado e irrepresentável
Da cognição incorporada a uma ontologia da percepção: o corpo e o mundo na Fenomenologia da percepção de Merleau-Ponty
Authors: Quirino André Gomes
Published: December 2017

Neste artigo, apresenta-se a modificação operada pela Fenomenologia da Percepção de Maurice Merleau-Ponty no estatuto metafísico do sujeito do conhecimento – segundo certa apropriação da obra pelo movimento da cognição incorporada –, e procura-se entender por que essa mesma transformação foi alterada no pensamento posterior de Merleau-Ponty. Nossa intenção é propor um tipo de reflexão que habilitaria a filosofia da mente contemporânea a preservar a descoberta da cognição incorporada sem estar sujeita aos contornos assumidos tardiamente pela fenomenologia merleau-pontyana
Dating archaeological pottery through optically stimulated thermoluminescence (OSL) and electron paramagnetic resonance (ESR)
Authors: Watanabe Shigueo , Sengupta Debashish
Published: December 2017

São descritas as propriedades de luminescência térmica ou óticamente estimulada em cristais iónicos, particularmente nos grãos de quartzo, visando suas aplicações na datação de vasos cerâmicos, terras queimadas, telhas e tijolos antigos. Essa luminescência é induzida pelas radiações provenientes de radioatividade natural do subsolo, onde as cerâmicas arqueológicas são coletadas
Southern Jê earthworks and burial mounds
Authors: Souza Jonas Gregorio de
Published: December 2017

Neste artigo comparo diferentes sítios de aterros e montículos funerários Jê escavados em Pinhal da Serra, Rio Grande do Sul. O primeiro tipo consiste em dois pequenos aterros circulares cercando montículos com sepultamentos cremados. O segundo apresenta um grande aterro circular unido a um muro retangular e cercando três montículos. A arquitetura dos sítios, o dispêndio de energia em sua construção e as atividades realizadas nos mesmos sugerem distinções hierárquicas entre os vários cemitérios
D ichotom y or com plem entarity: the eternal debates about the concepts o f style and function
Authors: Mageste Leandro Elias Canaan , Oliveira Ana Paula De Paula Loures
Published: December 2017

Os debates envolvendo as definições de estilo e função vêm sendo conduzidos na Arqueologia por mais de um século. Uma das questões que continua a configurar como um impasse é a pertinência de uma dicotomia entre o que poderia ser considerado estilístico e/ou funcional no estudo da cultura material. Frente a este cenário, o presente trabalho se propõe a discutir a pertinência de tais proposições no estudo da cerâmica do sítio Córrego do Maranhão, Carangola-MG
Archaeology in the water mirrors: the systematic inventory of underwater archaeological heritage of the Lower São Francisco River - Sergipe, Alagoas
Authors: Santos Luis Felipe Freire Dantas
Published: December 2017

Este artigo apresenta o projeto de pesquisa que pretende realizar o levantamento, em diferentes fontes, do patrimônio arqueológico subaquático existente na região do Baixo Rio São Francisco, expor os meios de aplicabilidade de um estudo sistemático in situ desses sítios submersos e, também, o seu inventário. Tal projeto possibilitará, assim, a produção de conhecimento sobre os sítios arqueológicos submersos na região, bem com o a divulgação dos resultados da pesquisa para todas as esferas da sociedade
Expanding frontiers: visiting archaeological sites on Sicily and South Italy
Authors: Rezende Regina Helena
Published: December 2017

Esta comunicação tem por objetivo apresentar como são organizados os sítios arqueológicos em uma realidade diversa da brasileira, a partir da experiência vivenciada por nós na Itália no ano de 2010. Nesta ocasião, visitam os 13 sítios arqueológicos na Sicília e no Sul da Itália, com o parte da pesquisa de campo que foi realizada para o desenvolvimento de nossa tese de doutorado. Esperamos, com esta apresentação, colocar em debate a forma com o o patrimônio cultural é vivenciado naquele país
Khóra and ásty in the Greek Western póleis
Authors: Custodio Christiane Teodoro
Published: December 2017

Na perspectiva dos espaços construídos, a pólis das colônias gregas localizadas no que atualmente denominam os Itália do Sul e Sicilia é com preendida como uma com unidade de cidadãos assentada em um território com posto pela ásty - uma área de maior urbanização, abrigando edifícios cívicos, religiosos e habitações - e a khóra - compreendendo áreas de cultivo, pastoreio, bosques e santuários. Desta forma, discutiremos a integração da khóra e da ásty a partir da observação de suas configurações espaciais e políticas. Analisarem os tanto elementos arqueológicamente identificáveis, como a articulação dos quadriculamentos intra muros e extra muros, quanto o sentido político da khóra colonial, tal quando ela própria adquire o sentido de fronteira ou quando das disposições da partilha de terras, caracterizadas pela desigualdade que constitui uma marca da estrutura fundiária da Grécia Arcaica. Com isso, buscam os configurar um quadro onde khóra e ásty constituem, ao mesmo tempo, uma unidade territorial e a ortogonalidade observada na organização das póleis coloniais corresponde às necessidades de uma nova realidade social e política dos assentamentos gregos do Ocidente
Wine and stone: Dionysus and the material expression of the theater on the urbanism of archaic and classical Greece
Authors: Argos João Esteiam De
Published: December 2017

O objetivo desta pesquisa é buscar uma melhor compreensão do papel desempenhado pelo culto de Dioniso na cidade grega da época arcaica e clássica. Partimos do princípio de que o teatro como instituição grega expressa a presença do culto de Dioniso na pólis e de que o ambiente construído expressa elementos organizacionais da sociedade e interage com ela. Nossa intenção é, a partir de uma amostragem definida, estudar o teatro grego em seus aspectos físicos/materiais, focalizando sua inserção no disciplinamento do espaço na cidade-estado grega. Ainda que seja impossível ignorar a documentação escrita e a bibliografia existente sobre o teatro grego na Atica, pretendemos ampliar a nossa perspectiva, lidando com material arqueológico proveniente de outras pólis. Nosso recorte cronológico estará constituído pelos séculos VI ao III a.C
Syracuse, Ancient City
Authors: Cordeiro Silvio L.
Published: December 2017

Uma das maiores cidades gregas na Antiguidade, Siracusa situa-se na maior ilha do Mar Mediterrâneo - a Sicília - no cruzamento de vias marítimas milenares, freqüentada por povos diversos na história. A partir de um relato de viagem da equipe do Laboratório de Estudos sobre a Cidade Antiga (LABECA MAE USP) à Sicília, em 2007, o documentário dirigido por Silvio Luiz Cordeiro mostra as impressões de seis siracusanos sobre a sua cidade: entre os tempos de um mesmo lugar, do passado remoto à vivência do presente, a memória de uma cidade viva.
‘Massilia, Phocaean city: myth or reality?’ Observations from the harbourcity relationship
Authors: Tacla Adriene Baron
Published: December 2017

Em 1973, Roland Martin definiu Massália com o a cidade foceia por excelência. Desde então muito tem-se especulado a respeito das relações dessa apoikía com sua cidade-mãe, Foceia, e a conseqüente manutenção de sua rede comercial e cultural no Mediterrâneo ocidental. Nesse sentido, os estudos acerca da identidade massaliota têm seguido rumo à definição de seu caráter singular, da mesm a forma que análises das cidades foceias no ocidente têm questionado a existência de um modelo foceu de cidade. Com esse cenário em mente, propomos, nesse trabalho, retomar a discussão da questão do caráter foceu em Massália. Tendo por base os achados arqueológicos, em particular aqueles do antigo Lacydon, bem como a documentação textual acerca dessa fundação colonial, discutiremos como porto e cidade se articulam na construção do “ideal” de cidade foceia e da identidade dos massaliotas em particular
Espelho, espelho meu: a literatura árabe
Authors: Gonalves Gláucia Renate
Published: December 2017

Num primeiro momento, o presente artigo discute a contribuição dos Estudos Culturais e do multiculturalismo para o estudo da literatura de imigrantes nos Estados Unidos. Em seguida, o ensaio problematiza termos como identidade, diferença e diversidade, buscando dessa forma questionar a classificação da produção literária norte
A Diglossia nas Comunidades Árabes
Authors: Nogueira Cléris Regina
Published: December 2017

Uma importante questão no estudo da língua árabe é a chamada “diglossia”. Devido à sua natureza diglóssica, o Árabe representa um dos casos mais extremos de coexistência entre duas normas claramente diferenciadas para a fala (dialetos) e para a escrita/leitura (Árabe Padrão). De fato, foi com base nas maiores diferenças entre o Árabe Padrão e os vários dialetos falados atualmente que a noção de diglossia foi inicialmente concebida. O objetivo deste artigo é dar um panorama de tais diferenças e da situação lingüística atual nos países árabes, com foco nas recentes discussões sobre a conexão entre a diglossia e outras normas lingüísticas emergentes nessas comunidades.
Livro das mil e uma noites
Authors: Codenhoto Christiane Damien
Published: December 2017

Livro das mil e uma noites. Tradução de Mamede Mustafa Jarouche, São Paulo: Globo, 2005, 2v.
As Metamorfoses da Universidade
Authors: Butor Michel
Published: December 2017

Conferência proferida na USP, em 1984, por ocasião das comemorações do Cinqüentenário
Cíntia, a musa de Propércio
Authors: Rangel Maria Lúcia Silveira
Published: December 2017

Estudo da personagem Cíntia, através da poesia elegíaca de Propércio: 1) personagem real ou fictícia? 2) paixão do Poeta - realidade ou recurso estilístico? Rápida menção de opiniões divergentes. Descrição da personagem pelo Poeta. Composição de um retrato: beleza física, habilidades (dança, música), tendências morais e psicológicas. Visão do amor properciano: dignificação e eternização da heroína
A Construção do sentido: um exemplo fotográfico persuasivo
Authors: Brait Beth
Published: December 2017

Ainda que os estudos sobre a argumentação e a persuasão estejam mais amplamente desenvolvidos no que diz respeito à linguagem verbal, o discurso visual pode também oferecer excelentes exemplos de construção ambígua do sentido, graças a processos específicos de produ­ ção enunciativa. Neste artigo, o objetivo é mostrar alguns aspectos enunciativos-discursivos que possibilitam transformar uma fotografia, aparentemente objetiva, em texto, em discurso fotográfico persuasivo
A Lira esfacelada do poeta (Uma interpretação dos desdobramentos do tema da viola quebrada na obra de Mário de Andrade)
Authors: Rufmoni Simone Rossinetti
Published: December 2017

O tema da canção “viola quebrada” de Mário de Andrade remete à metáfora de sua lira e de seu processo de criação poética. A Lira esfacelada na figura da Viola quebrada é um tema reincidente em sua obra cujas alterações implicam a correlação com o percurso do poeta às voltas com a questão da cultura popular e dos rumos da arte erudita no país. A viola adquire proporções de emblema; ela é os sofrimentos do poeta, suas desilusões e o aprofundamento da consci­ ência de crise, confluindo na crescente angústia que permeia a intenção sacrificial de sua obra
Palavra de Jornal - A Linguagem Intermediária
Authors: Chinellato Thais Montenegro
Published: December 2017

Procura-se identificar o nível médio de linguagem no jomal Folha de S. Paulo, a partir de diferentes exemplos de suas editorias
A Literatura como visão do Novo Mundo
Authors: Brandão Roberto De Oliveira
Published: December 2017

A presente análise procura mostrar corno os primeiros colonizadores que escreveram sobre o Brasil viram-no a partir das suas próprias experiências, projetos e valores. Se no início também os nossos poetas assumiram a identidade cultural e literária da Metrópole, com o tempo desenvolveriam eles uma nova sensibilidade, associada a novos modos de ver e sentir suas relações com o meio cujas conseqüências se refletiriam na poesia aqui produzida
O Silêncio, a palavra e o Sábio
Authors: Szpiczkowski Ana
Published: December 2017

A comunicação pode se dar tanto pela palavra como pelo süéncio. O silêncio, como meio de comunicação, tem significados especiais, que variam em relação ao contexto no qual se insere, e implica o saber escutar a mensagem do sábio, seja ela implícita ou explícita. Conceituar e explicar o papel do sábio e suas implicações no processo de ensinar e se fa zer escutar, de acordo com o texto do tratado de Pirkei Avot é, portanto, a proposta deste estudo
A Praça, o Povo e o Poeta
Authors: Aguiar Flávio
Published: December 2017

O autor apresenta a trajetória da poesia de Castro Alves e sua ligação com o contexto sócio-político da época
O Proletário aparece
Authors: Ceschin Osvaldo Humberto L.
Published: December 2017

O trabalho, depois de considerar alguns elementos históricos da palavra p ro le tá rio , examina algumas de sua principais ocorrências em textos da literatura brasileira do século XIX especialmente, e comenta seu emprego num dos Cromos” publicados por B. Lopes em 1881.
A Mulher e o silêncio nas peças de Shakespeare
Authors: Guedes Peonia Viana
Published: December 2017

A dialética entre o silêncio e a linguagem é frequentemente utilizada para definir a relação drámatica entre as personagens de uma peça O silêncio das personagens femininas em algumas das obras de Shakespeare reflete as expectativas sociais do século XIV sobre o papel e comportamento dos gêneros. O silêncio de Ofélia em Hamlet e de Cordélia em O Rei Lear ilustram a falta de alternativas positivas para as mulheres na sociedade patriarcal e as conseqüências dos valores opressivos e repressivos que caracterizam o universo das tragédias de Shakespeare.
A busca da integração humana do índio na primeira gramática da Língua Quêchua
Authors: Navarro Eduardo De Almeida
Published: December 2017

Os debates acerca da condição humana do índio, que no século XVI dividiram os pensadores europeus, fora m muito enriquecidos com a publicação das primeiras gramáticas das línguas indígenas, que revelaram que essa s línguas não tinham um estatuto d e inferioridade em relação ao latim ou às línguas européias modernas. Notável, n esse particular, foi a obra de Frei Domingos de Santo Thomas, autor da primeira gramática da língua Quêchua, do antigo império inca
Uma chave para o conhecimento geográfico
Authors: Moraes Gabino Ribeiro
Published: December 2017

Este artigo caracteriza-se por uma proposta de instrumentalização do ensino de Geografia na perspectiva da interdisciplinaridade. Uma experiência de simbiose entre Geografia e Literatura para alunos do terceiro ciclo do Ensino Fundamental. Os dados levantados sugerem a viabilização da obra A chave do tamanho, de Monteiro Lobato, como recurso didático na prática do ensino de Geografia. Além de facilitar o entendimento da noção de escala geográfica, esta proposta oferece, também, novas oportunidades para facilitar a compreensão da realidade local e global.
Salgado, o inesperado: o Brasil nos quatro romances de Plínio Salgado
Authors: Aguiar Flávio
Published: December 2017

Este artigo situa, em primeiro lugar, a trajetória biográfica e política de Plínio Salgado, o líder do Integralismo brasileiro. A seguir, descreve e analisa seus quatro romances, caracterizando-os dentro do panorama da década de 30 no Brasil e seu papel no projeto político do autor. A análise também aborda a crítica social que o autor faz à sociedade brasileira do tempo