bluuebunny/crossref_metadata_2025 huggingface dataset:
Nintedanib reduces corticosteroid resistance pulmonary fibrosis induced by bleomycin in mice by increasing the expression of β3 and β6 integrins
Authors: Alghamdi Doha , Kawy Hala , Damanhouri Zoheir
Published: May 2023

Background: Pulmonary fibrosis is a progressive lung disorder that occurs by lung injury and scarring of the lung tissue. This injury makes the lung thickened and stiff causing difficulty to breathe. Corticosteroid resistance pulmonary fibrosis is a major health problem. Bleomycin is an anti-cancer agent, it induces pulmonary fibrosis resistance to corticosteroid therapy, this study aimed to determine the effectiveness of nintedanib (NIN) a tyrosine kinase inhibitor on corticosteroid resistance pulmonary fibrosis induced by bleomycin in mice. Methods: Sixty albino male adult mice were used in this study. The mice were divided into five groups (n=12) at random. control group, the BLM group received a single dose of bleomycin (BLM); 2U/kg by endotracheal instillation, the BLM+MP group received bleomycin and methylprednisolone (MP) 10mg/kg/day by gastric gavage, BLM+NIN group received BLM and NIN, 60mg/kg/day by gastric gavage and the combined treatment group received BLM, NIN, and MP. All groups were sacrificed after the last dose of treatment on day 7 (acute stage) and day 28 (chronic stage). The lung tissues were obtained for biochemical analysis, gene expression, and histopathological examination at the end of the experiment. Results: After 7 days of treatments, BLM+NIN and BLM + NIN + MP groups showed a significant (P<0.05) decrease in the contents of interleukin-2, interleukin-4, interferon-gamma, tumor necrosis factor-alpha, Malondialdehyde with an increase in the glutathione content in lung tissue compared to MP group. Also, they showed a significant decrease in the lung water content compared to the BLM group treated with MP. After 28 days, both NIN groups showed a significant reduction in hydroxyproline, and transforming growth factor beta (β) contents in the lung tissues compared to the MP group, and they showed a positive effect on the expression of β3 and β6 integrins compared to the negative effect of the MP group. Upon histopathology examination, the BLM+NIN group and BLM + NIN + MP groups showed significant improvement compared to the MP group by hematoxylin and eosin (H and E) and Masson’s trichrome stains. Immunohistochemical staining revealed negative BCL-2 expression in the cytoplasm of bronchiolar epithelium in BLM+NIN and BLM + NIN + MP groups after 7 and 28 days of treatment. Morphometric studies of lung tissue showed significant improvement in pathological changes induced by BLM in the BLM+NIN group and BLM + NIN + MP groups. Conclusion: Altogether, our data indicate that NIN overcame corticosteroid resistance pulmonary fibrosis induced by bleomycin in mice mainly by decreasing TGF-β and improving the expression of β3 and β6 integrins.
Effectiveness of a Pilot Health Education Program on Knowledge and Attitude Toward Dealing with Diabetics
Authors: Alajlan Reyof , Alyahya Ruba , Alenzi Fotoun , Almouh Raghad , Bakry Huny
Published: May 2023

Background: This study aimed to measure the effectiveness of a pilot health education programme on Xxx University student’s knowledge and attitudes towards dealing with diabetic patients. Methods: A quasi-experimental study was conducted among 60 students at Xxx University through two groups, intervention and comparative, from January to April 2019. Results: There was a statistically significant difference between the pre-and post-test total knowledge of the intervention group. Moreover, there was no significant difference between the pre-and post-test total knowledge of the comparative group, and there was no significant difference between the pre-and post-test attitudes of the intervention and comparative groups. Conclusion: The health education programme was effective in improving the knowledge of the participants. It is recommended that family members and caregivers be involved in diabetes education sessions.
Urban energy systems in India :
Authors: Signh Naresh , Israni Poorva
Published: May 2023

The fossil fuel-based energy systems require accelerated transitioning towards renewable energy provisions in order to reduce carbon emissions. Urban energy systems are commonly called sociotechnological systems, that have interconnections with the political, environmental, and economic landscape of the urban areas. These inter-sectoral linkages, the constant evolution of stakeholder's priorities and relationships, and their conflicting objectives in the urban energy landscape make urban energy systems a complex system. Asserting the need to comprehend the challenges of transitioning towards sustainable energy systems, it appears desirable to view urban energy systems as complex systems. Based on recent literature on urban energy systems and complex systems thinking, the paper initially discusses the characteristics of urban energy systems. It aims to demonstrate the relationship of urban energy systems with social, technological, environmental, political, and economic aspects of urban areas. It further emphasizes the need and the approaches to recognise urban energy systems as complex systems due to the presence of factors, such as multiple stakeholders, the interconnectedness of the agents, changing dynamics, and adaptive processes in the systems. This paper takes the case study of the city setting of Bhopal, Madhya Pradesh, and considers its urban Solar City Master Plan to better understand the essence of complex energy systems. Against this background, the aim of the paper is to understand the application of complexity economics and systems thinking to the transition of urban energy systems from fossil fuels to renewables. In addition, the paper intends to explore how examining the urban energy systems through the lens of complexity economics and systems thinking can be valuable in formulating policy interventions towards sustainable urban energy transitions.
Faktor – Faktor Yang Berhubungan Dengan Kejadian Penyalahgunaan Narkoba Di Kecamatan Baturaja Timur Tahun 2022
Authors: Novitry Fera , Lilia Deli , Sarwoko Sabtian
Published: May 2023

According to data from the Ogan Komering Ulu Regency, the perpetrators of narcotics crimes committed in 2019 there were 75 cases of which 86% were grouped in the productive age of 18-40 years, in 2020 there were 82 cases and 90% were grouped in the productive age of 18-40 years, and In 2021 in the jurisdiction of the Ogan Komering Ulu Police, there were 95 cases of which 96% were grouped in the productive age of 18-40 years of narcotics abuse. The research design used is a quantitative research design with a case-control research approach. The population is all residents in East Baturaja sub-district, East Baturaja Police has 105,076 residents aged 18-40 years totaling 58 cases. The sample in this study is Cases are productive age 18-40 years who are really drug users as many as 58 people. While the controls are productive age 18-40 years who really do not use drugs as many as 58 people.It is known that the proportion of respondents who have bad social relationships and become drug abusers is 70.7% greater than the proportion of respondents who have good social relationships and become drug abusers as much as 12.2%. It is known that the proportion of respondents with heavy workloads becomes drug abuse as much as 67.7%, which is greater than the proportion of respondents with light workloads who become drug abusers as much as 22.2%. It is known that the proportion of respondents with severe stress who become drug abusers is 66.2% greater than the proportion of respondents with moderate stress who become drug abusers as much as 17.9%.The results of the chi square test get p value 0.000 < (0.5) which means there is a relationship between environmental association and drug abuse. The results of the chi square test get p value 0.000 < (0.5) which means there is a relationship between workload and abuse drugs. The results of the chi square test obtained p value 0.000 < (0.5) which means that there is a relationship between stress and drug abuse.
APPLICATION GIS IDENTIFY LAND AREA SUITABLE FOR RUBBER AND COFFEE TREES TO AGRICULTURE RESTRUCTURE GIA LAI PROVINCE
Authors: Bich Nguyen Thi , Phuong Hoang Xuan
Published: May 2023

Gia Lai has great potential for developing agricultural production, and it is home to a large crop industrial material area in Vietnam. It boasts nearly 100,000 hectares of coffee and nearly 90,000 hectares of rubber. The area has immense potential to develop its agricultural production due to its unique characteristics of soil and climate, which can support a rich diversity of plants and animal with high economic value. By creating areas for intensive agricultural production and concentrating on commodity products with a competitive advantage, Gia Lai can improve the efficiency of its agricultural restructuring. To achieve this goal, this research has utilized the Land Evaluation Method of the FAO method and GIS to identify suitable land areas for rubber and coffee trees to restructure agriculture in Gia Lai province. the results indicate that the land suitability for coffee trees is mainly moderately suitable (S2) with 86,163 hectares of land suitable for cultivation. Coffee trees are primarily grown in districts such as Chu Pah, Dak Doa, Chu Se and Ia Grai. On the other hand, the land suitability for rubber trees is mainly moderately suitable (S2) with 60,000 hectares of land suitable for cultivation. Rubber trees are primarily grown in districts such as Chu Pah, Dak Doa, Chu Se, Ia Grai and Chu Prong. These areas are characterized by the distribution of red basaltic soils, rainfall exceeding 2500 mm, and a favorable climate for the development of industrial plants.
USING PLANETSCOPE DATA TO ESTIMATE CARBON SEQUESTRATION OF MANGROVE FORESTS: A CASE STUDY IN TIEN YEN DISTRICT, QUANG NINH PROVINCE
Authors: Hoa Nguyen Hai , Son Ha Tri , Linh Nghiem Thi , Vicent Daniel Ojeda de , Linh Nguyen Ngoc
Published: May 2023

Mangrove forests, typically found along tropical and subtropical coastlines, have a crucial role in preventing coastal erosion, mitigating the effects of wave actions, and safeguarding coastal habitats. This study utilized PlanetScope mangrove forests and a Combined Mangrove Recognition Index (CMRI), which was suitable for detecting mangrove cover along the coast of Tien Yen district with an overall accuracy of over 93.0% and a Kappa coefficient greater than 0.90 for the selected years. The total area of coastal mangrove forests along the coast of Tien Yen, Quang Ninh province has increased by 137.7 ha in 2023 compared to 2020. The total AGB and AGC of mangrove forests were estimated at 241,730,970 tons and 114,822,211 tons in 2023, respectively. The total CO2 sequestration was estimated at 421,397,514 tons in 2023, which represents a decrease of 17,813,872.1 tons compared to 2020. The study highly suggests the adoption of blue carbon approach for sustainable mangrove management in Tien Yen district, including Payment for Ecosystem Services (PES) schemes. However, certain key factors, such as increasing awareness of the value of the mangrove ecosystem, promoting the involvement of local communities, and revising policy issues related to PES, need to be addressed to ensure the success of the mangrove blue carbon option in Tien Yen district.
DESIGN AND MANUFACTURE A BANANA FIBER EXTRACTION MACHINE FOR SMALL AND MEDIUM-SCALE HANDICRAFT PRODUCTION
Authors: Chi Tran Cong , Hoa Ta Thi Phuong , Dai Vu Huy , Tinh Pham Van
Published: May 2023

Currently, by-products from banana trees such as banana sheath and leaves are discarded, which is very wasteful and causes environmental pollution. However, in the world, these materials are considered a significant resource that can be used to produce natural fibers and create handicraft products that are aesthetically valuable, economically viable, and environmentally friendly. This article introduces the research results on designing and manufacturing a banana fiber extraction machine for the production of handicrafts on a small to medium scale in Vietnam. The machine was designed through calculations, model building, and software testing before being manufactured and assembled. After assembly and completion, the banana fiber extraction machine was tested under no load and under load to evaluate its fiber processing capability. Three different processing modes corresponding to different motor speeds of 750 rpm, 900 rpm, and 1,050 rpm were tested to evaluate the banana fiber extraction rate. The results showed that the machine functioned reliably across all three modes, with extraction rates of 10.1%, 11.2%, and 10.8% achieved at motor speeds of 750, 900, and 1050 rpm, respectively. Therefore, this banana fiber extraction machine can be used to extract banana fibers and meet the requirements of producing handicraft materials in Vietnam.
The Development of the Strategic Plan with Family, Community, and Buddhism to Build Social Protection Against Drugs in Thai Vulnerable Youth
Authors: Promsri Prasong , Khetjoi Sitthiporn , Chuachan Nathaorn , Chompromma Prasert , Worabuttara Thaworn , Deeod Pongmanut , Uthaphan Phattharachai , Neadpuckdee Radchaneeboon , Chachikul Prachan
Published: May 2023

The current study aims to investigate the effects of a strategic plan developed by the involvement of the family, community, and Buddhist institutions in Thai vulnerable youth knowledge, attitudes, and behavioral changes. The sample included 302 vulnerable adolescents from Khon Kaen, Thailand. The utilization of systematic sampling was observed based on income, marital status, and neighborhood. 10 governmental employees also took part in an interview designed to investigate the participants’ changes in behaviors of drug abuse. The instruments include a strategic plan for the drug prevention of vulnerable children, a test of drug prevention knowledge, a satisfaction survey, and a semi-structured interview. The data were obtained by a pre-post-test on the samples’ knowledge of drug prevention, an attitude survey, and an authorities’ interview. Frequency, percentage, mean score, SD, and t-test were used to examine the data. The content analysis assessed qualitative data. The findings reveal how a strategic plan designed by institutions concerned with human development led to the development of knowledge, attitudes, and positive behavioral changes among at-risk teenagers.
Land Financing-Led Urbanization in China: Evolution, Scale and Lessons
Authors: Liu Minquan , Cui Yuming
Published: May 2023

The role of land financing in China’s rapid urbanization and economic development in recent decades has been much debated. This paper reviews and discusses the emergence and evolution of land financing both as a source of revenue and as a financing vehicle for local governments in China, and the contribution it makes to rapid urbanization in the country through its impact on the real estate sector. Urbanization as a possible independent driver for a country’s economic development is also discussed, using China’s case as a concrete example. The paper further touches on the possible reference value of the Chinese case to other countries, taking into account both the preconditions for a successful land financing strategy, and inherent risks with such a strategy. The contribution of land financing to local governments’ debt burden in China, which has recently been an international concern, is also discussed.
Examination of data collection methods for pragmatic competence assessment of EFL learners
Authors: Pan Zhaoyi
Published: May 2023

This research examined whether three commonly used data collection methods, namely the discourse completion test, role-play tasks, and naturally occurring data, are appropriate data collection methods for the assessment of the pragmatic competence of English as a foreign language (EFL) learners. Moreover, the study used the three data collection methods to determine whether there was a significant correlation between the grammatical competence and the pragmatic competence of EFL learners. Participants included 100 Asian EFL learners at two English proficiency levels. This research found a significant difference in the speech act performance of the EFL learners between each pair of the three data collection methods. The results suggested that the naturally occurring data collection method revealed the speech act performance of the EFL learners at its optimal. Furthermore, a significant correlation was found between the grammatical competence and the pragmatic competence of the EFL learners by using the naturally occurring data collection method. Both results indicated that the naturally occurring data collection methods may be more appropriate for the assessment of the pragmatic competence of EFL learners. Further empirical experiments should be conducted to ascertain the correlation between grammatical competence and pragmatic competence.
EFFECT OF ELASTOMERIC SEPARATOR ON MICROBIAL COUNT IN GINGIVAL CREVICULAR FLUID
Authors: Sattar Khan Samia , Asad Saad , Hussain Umar
Published: May 2023

Background: The separators are a preliminary step for band insertion, but there is a potential risk of bacteraemia during their placement, particularly in susceptible patients. The objective of the study is to determine the effect of separators on the bacterial count in gingival crevicular fluid (GCF) and to assess the efficacy of chlorhexidine mouth rinse and saline irrigation in the reduction of the bacterial count. Methods: This randomized controlled trial was conducted on 51 participants who were divided into three equal groups randomly (brushing only/control, saline irrigation, and 2% chlorhexidine mouthwash rinse). The inclusion criteria were age between 18–25 years, good oral hygiene, gingival and plaque index <1, no previous orthodontic treatment, and healthy individuals. The bacterial count was obtained from GCF samples after two hours, on the third day, and on the seventh day. Kruskal Wallis test was used to compare the bacterial count among the three groups, and post hoc analysis was done using Dunn's test. Friedman test was applied to see the difference at three-time points in each group. Results: In both saline and chlorhexidine groups the mean bacterial count decreased significantly from baseline to 3rd day and 7th day after separator placement (p<0.001). For the third day, a significant difference was found in control versus saline and control versus chlorhexidine. No significant difference was found between saline and chlorhexidine on the third day. Similar results were found on the 7th day. For controls, the bacterial count increased with time and for both saline and chlorhexidine groups the bacterial count decreased. The highest decrease in the bacterial count was found for the chlorhexidine group. Conclusion: After the placement of separators, there was an increase in the bacterial count in GCF. Notably, chlorhexidine was found to be more effective than saline irrigation in reducing the bacterial count.
OPTIMIZING THE DAILY UNITS OF INSULIN; INSULIN DEGLUDEC ASPART VERSUS PREMIXED INSULIN ASPART IN THE STANDARD OF CARE REGIMEN FOR TYPE 2 DIABETICS
Authors: Malik Komal Mumtaz , Farhat Kulsoom , Ali Shabana , Noor Mudassar , Ahmad Bilal
Published: May 2023

B
Background: This study aimed to evaluate the impact of Insulin Degludec Aspart on daily insulin dose in comparison with premixed insulin aspart. Methods: It was a Quasi-Experimental study conducted in the Department of Pharmacology, Army Medical College, National University of Medical Sciences, Rawalpindi and the Department of Medicine, Pak Emirates Military Hospital, Rawalpindi. One hundred and twenty participants with documented type 2 diabetes, taking premixed insulin aspart therapy were enrolled in the study. Sixty participants were substituted with insulin degludec aspart from premixed insulin aspart. Daily units of insulin were recorded for 12 weeks and compared for both groups. SPSS version 26 was used for analysing the study results. Results: Participants of the insulin degludec aspart group showed a significant reduction in the daily insulin dose compared to the premixed insulin aspart group. Fifty-two units per day were administered in the participants of the premixed insulin aspart patients while insulin degludec aspart participants received 40 units of median daily insulin dose (p-value<0.001).
Conclusion: Insulin degludec aspart proved superior to premixed insulin aspart in a reduction in the daily dose of insulin with insulin degludec aspart
De gewijzigde ontslagbescherming van de klokkenluider
Authors: Hidajat-Engelsman Suzanne
Published: May 2023

De gewijzigde ontslagbescherming van de klokkenluider

De Europese klokkenluidersrichtlijn is in Nederland geïmplementeerd in de Wet bescherming klokkenluiders. Door deze implementatie is de ontslagbescherming van klokkenluiders veranderd. Dit artikel brengt die gewijzigde ontslagbescherming in kaart. Daarbij worden ook aandachtspunten en onduidelijkheden gesignaleerd.
Os jogos no ensino de funções: uma experiência vivenciada por licenciandos de matemática na educação básica
Authors: De Brito Leonardo Lira , De Abreu Jair Dias , Martins Fabíola da Cruz , Freitas Tiêgo dos Santos
Published: May 2023

No presente artigo objetivamos apresentar experiências desenvolvidas com a utilização de jogos no ensino de funções, vivenciadas por licenciandos em matemática na Educação Básica. O trabalho é fruto da disciplina Metodologia do Ensino de Matemática III, do curso de Licenciatura em Matemática de uma Universidade Federal localizada na Paraíba, que teve como proposta a elaboração de jogos para o ensino de funções, de modo que busquem atrair o aluno ao conteúdo a ser trabalhado e proporcionem um ensino com mais compreensão, interativo e dinamizado. Para tanto, foram exploradas as funções quadrática, exponencial e logarítmica. Observamos, no desenvolvimento das atividades e a partir das análises realizadas pelos alunos, a importância das vivências destes professores em formação na educação básica. Além disso, evidenciamos também a ausência na literatura de materiais disponíveis para a abordagem das funções trabalhadas, sobretudo, das funções exponencial e logarítmica, o que enaltece o nosso trabalho, não somente para os licenciandos participantes, mas para professores, futuros professores e a comunidade científica.
Uma abordagem de projetos de engenharia na educação básica utilizando simulação on-line
Authors: Anastácio Darlan da Silva , De Oliveira Flávia Camila Morais , Alcoforado Maria de Lourdes Melo Guedes
Published: May 2023

Este documento apresenta uma abordagem para imersão inicial de alunos da educação básica em aplicações de engenharias elétricas, enfatizando a contextualização entre teoria e prática das disciplinas estudadas em sala de aula. Elabora-se um projeto de automação para irrigação de um jardim em uma ferramenta on-line de simulações de circuitos elétricos a fim de estimular o interesse dos alunos a ingressar em cursos de engenharia.
Aplicação de essencial de tea tree (melaleuca alternifolia) e óleo bálsamo de copaíba (copaifera officinalis) no controle de staphylococcus aureus em carne de frango cozida
Authors: Gondim Renata Freire Alves , Da Silva Jaqueline Damos , De Sá Silva Claudileide
Published: May 2023

Introdução: A crescente industrialização de aves ressuscita o frequente cenário envolvendo doenças de origem alimentar, em especial, as toxi-infecções decorrentes de Staphylococcus aureus, reivindicando a necessária adesão e reestruturação de medidas profiláticas. Objetivos: Avaliar a efetividade do óleo bálsamo de copaíba (Copaifera officinalis) e essencial de tea tree (Melaleuca alternifólia) no controle de Staphylococcus aureus experimentalmente inoculado em carne de frango cozida. Metodologia: determinação da composição dos óleos, do teor antioxidante e da atividade antimicrobiana perante S. aureus inoculados em frangos cozidos Resultados: o óleo essencial de tea tree (Melaleuca alternifólia) apresentou em sua composição 43,1% de terpinen-4-ol, enquanto o óleo bálsamo de copaíba (Copaifera officinalis) 70% de β-cariofileno. O teor antioxidante necessário à inibição de 50% dos radicais livres é 2,59 µg/mL para C. officinalis e 15,9 µg/mL para M. alternifolia, o que corrobora a potencial eficiência antioxidante. Ambos os óleos foram eficazes em inibir o crescimento do Staphylococcus aureus sob inoculação in vitro, porém, quando inoculado no frango, o mesmo efeito antimicrobiano não foi observado. Conclusão: Embora a inibição de S. aureus a partir dos óleos essenciais não tenha sido alcançada após a aplicação na carne, considera-se que o pH e o substrato (matriz alimentar) tenham potencializado a proliferação microbiológica. Em contrapartida, a detecção do teor antioxidante corrobora para o aumento do tempo de vida da prateleira dos alimentos.
The Interaction of Shame and Urgency in Non-Suicidal Self-Injury and Suicide Attempts
Authors: Sandel-Fernandez Devon , Modavi Kiana , Swerdlow Benjamin , Tharp Jordan , Timpano Kiara , Johnson Sheri
Published: May 2023

Urgency, the trait-like tendency to respond to heightened emotion states with rash action, has been associated with both non-suicidal self-injury (NSSI) and suicide attempts (Lynam et al., 2011). Limited research has sought to identify specific emotions that may trigger NSSI or suicide attempts for those with high urgency. We examined shame as a candidate emotion. We hypothesized that greater shame-proneness, in combination with greater urgency, would explain unique variance in NSSI and suicide attempt history in two community samples (Ns = 192 and 225). Logistic and negative binomial regression analyses examined the effects of shame, urgency, and their interaction on the presence (vs. absence) and frequency of NSSI and suicide attempts. The proposed interaction of shame and urgency was related to greater risk and frequency of NSSI and suicide attempts when examining simple slopes, across the six models tested, particularly when urgency was high. Further research should examine shame as a trigger for self-harm in the context of heightened urgency using time series designs.
EDUCAÇÃO ALIMENTAR: UM RELATO DE EXPERIÊNCIA COM EFEITO PRÁTICO
Authors: Pinheiro Maria Hipólito Almeida , Fernandes Marcela de Melo
Published: May 2023

O termo saúde, pode ser definido por múltiplos aspectos, que combinados, auxiliam e beneficiam o bem-estar físico, mental, social e espiritual. Sob o ponto de vista do processo saúde-doença, as suas múltiplas dimensões e objetos de conhecimento envolvidos, aproximam a Educação Física Escolar, do tema transversal saúde, no currículo escolar. Portanto, o trabalho teve como objetivo proporcionar a conscientização e assimilação sobre alimentação, nutrição e das doenças relacionadas às deficiências nutricionais para promover autonomia e melhorar a qualidade de vida dos alunos. O presente relato de experiência, refere-se ao projeto educacional “Educação Alimentar: Um recurso didático para um efeito prático”, realizado durante três semanas. De maneira geral, os resultados se mostraram positivos quanto à adesão de um estilo de vida mais saudável, quanto à autonomia para tomar decisões sobre consumo de alimentos prejudiciais e benéficos para saúde, quanto à preocupação em relação às doenças relacionadas às deficiências nutricionais e principalmente quanto à participação e engajamento nas aulas. Em conclusão, a principal barreira que a Educação Física escolar tem esbarrado e encontrado dificuldades para transpassar é o fenômeno do sedentarismo, associado ao aumento da má alimentação. Portanto, medidas precisam ser tomadas para que os efeitos no futuro não sejam tão catastróficos.
Televizyon Yayıncılığında Dijitalleşme ile Değişen Yayıncılık
Authors: ÇAKIR Hilal Gamze , BOLAT Nursel
Published: May 2023

Hızla gelişen internet ve yeni medya teknolojileri toplumda köklü değişikliklere sebep olurken, iletişim pratiklerini de dönüştürmüştür. Yeni medyanın bireylere sunduğu en önemli özellik, etkileşimli iletişimdir. Geleneksel medyada tek taraflı bir iletişim söz konusuyken, yeni medya teknolojileri bu algıyı tamamen yıkmış, hatta izleyicilerin aktif olarak yayınlara katılıp, içerik belirlemesine olanak sağlamıştır. Çalışmada, Samsun’un internet televizyonlarının bir haftalık içerikleri incelenerek, giderek değişim gösteren teknolojiye uyum süreçleri anlamlandırılmaya çalışılmıştır. Değişen televizyon yayıncılığında izleyicinin etkisi, yayıncıların gözüyle değerlendirilmiştir. İnternet televizyonluğunun yoğun olduğu bu dönemde Samsun’da izleyicilerin en çok ne izlemek istediği, hem içerik analizi yöntemi ile ortaya çıkarılmış hem de yayıncılarla yapılan derinlemesine mülakat ile birlikte harmanlanarak okuyucuya sunulmuştur. Araştırmada nitel araştırma yöntemlerinden derinlemesine mülakat tekniği kullanılırken, sorular yarı yapılandırılmış olarak belirlenmiştir. Araştırmanın örneklemini, Samsun merkezde yayın yapan internet televizyonlarında çeşitli pozisyonlarda görev alan isimler oluşturmaktadır. Elde edilen bulgular söylem analizi yöntemi ile analiz edilerek, internet televizyonlarının bir haftalık yayınları da içerik analizi yöntemi ile analiz edilmiş ikisi birleştirilerek sonuca ulaşılmıştır.
Envejecimiento contemporáneo: ¿bonus o bonus?
Authors: Silva José Vitor da , Nascimento Rosa Maria do , Loiola Tatiana , Pereira Bruna da Graça Macêdo , Ramos Márcio Daniel Nicodemos
Published: May 2023

Verificar el estado de salud del anciano para actuar en el mundo del trabajo e identificar los prejuicios sociales que enfrenta en su cotidiano. Se realizó una encuesta sobre las condiciones de salud, capacidad e interés en el trabajo de los ancianos. Esta búsqueda se realizó utilizando las siguientes bases de datos: Scientific Electronic Library Online (Scielo); Biblioteca Nacional de Medicina (Pubmed); Literatura Latinoamericana y del Caribe en Ciencias de la Salud (LILACS); Biblioteca Virtual en Salud (MEDLINE/BIREME), utilizando los siguientes descriptores tanto en portugués como en inglés: “Anciano”; "trabajar"; “Prejuicio”, “Longevidad” y “Calidad de Vida”. Se constató que los ancianos contemporáneos, desde el punto de vista de la salud, están debidamente preparados para la inserción o reinserción en el mundo del trabajo. Sus prejuicios sociales son diversos, lo que dificulta su desempeño social.
Potencial de los análogos de dillapiol para su uso en enfermedades desatendidas, con énfasis en la leishmaniasis cutánea: una revisión de la literatura
Authors: Barros Angela Maria Comapa , Pinto Ana Cristina da Silva , Guilhon-Simplicio Fernanda , Chaves Francisco Celio Maia , Lima Emerson Silva , Franco Antonia Maria Ramos
Published: May 2023

Las Enfermedades Tropicales Desatendidas (NTD, por sus siglas en inglés) son un grupo de enfermedades que afectan principalmente a la población de países tropicales y en desarrollo de ingresos bajos a medios. En los últimos años, en el panorama internacional, ha habido debates sobre las formas de prevenir, combatir y erradicar las enfermedades tropicales desatendidas, así como investigaciones para desarrollar nuevos fármacos que ayuden en el tratamiento de estas enfermedades, donde a través de la literatura hemos obtenido numerosos estudios científicos que muestran moléculas bioactivas de plantas con actividades biológicas, entre ellas Piper aduncum, ya que su compuesto mayoritario, el dilapiol, tiene una estructura química natural que puede ser modificada mediante semisíntesis, una alternativa para la obtención de nuevas moléculas activas, estos análogos del dilapiol, probados en enfermedades desatendidas, principalmente contra la leishmaniasis cutánea, inhibiendo las formas promastigotes y amastigotes de Leishmania de varias especies.
Análisis del Diseño Geométrico y Desempeño de Seguridad del Tramo Curvo Ubicado en el Km. 448 de la Carretera BR – 101
Authors: Teixeira Niel Nascimento , Jesus Diana Santos de , Vieira João Ribeiro Santana
Published: May 2023

En vista de la alta tasa de accidentes ocurridos en el tramo curvo ubicado en la carretera BR 101, Km 448 - Bahía, conocida popularmente como la "curva del sacerdote", el presente estudio realizó un diagnóstico de las características geométricas a el compromiso de seguridad del segmento, a partir del análisis de los datos sobre accidentes de tránsito en los últimos seis años ocurridos en esta curva ubicada en la ciudad de Aurelino Leal. A través de los resultados obtenidos, se pudo concluir que el tramo es un segmento crítico, y que se encontraron altas inconsistencias en la geometría (en la superelevación, en el ancho del carril, en la rampa máxima y en la distancia de visibilidad de la parada) del tramo de la carretera federal, que combinadas, estaban directamente relacionadas con su bajo desempeño de seguridad.
La industria alimentaria y la manipulación de las masas a través de la publicidad
Authors: Santos Ingrid Aparecida Martins dos , Milani Cassia Ellen
Published: May 2023

La industria alimentaria surgió en el siglo XVII, después de la Revolución Industrial, y ganó fuerza con la globalización y el auge del capitalismo en los años 90. Esto se debió al nuevo formato de la sociedad, que pasó de ser principalmente agraria y pastoral, con un estilo de vida que seguía los patrones de la naturaleza, a casi completamente urbano, con la noción de tiempo modificada y mucho más acelerada. La creciente demanda de productividad, al principio en el trabajo en fábricas, y ahora en las grandes empresas, ha provocado que se realicen adaptaciones en la vida de las personas , y de esta manera también en los hábitos alimenticios. Cambiaron, volviéndose más prácticos y, en consecuencia, menos conscientes. La alienación, la falta de tiempo libre y el estrés forman el escenario perfecto para que la industria alimentaria venda sus productos, incluso perjudicando la salud de los consumidores. La empresa se haconvertido en el principal impulsor de los productos industrializados, vendiendo una imagen distorsionada que manipula la elección de los compradores. Las estrategias de neuromarketing, las escalas cromáticas , los eslóganes, la música y el packaging con imágenes de personajes famosos y artistas desvían la atención de ingredientes controvertidos, provocando que la persona no sabe lo que está consumiendo. El uso de sustancias con alto poder adictivo, como el azúcar, las grasas, el sodio y los aditivos químicos crean dependencia en el cuerpo, llevando al consumidor a buscar siempre ese alimento, en cantidades crecientes y con mayor frecuencia. Todo ello hace que la industria alimentaria cree su propio mercado de consumo, en un ciclo del que solo es posible escapar con concienciación, educación alimentaria y, sobre todo, sentido común. crítico, para que la población pueda elegir qué comer libre y conscientemente, conociendo los impactos de sus decisiones.
Evaluación del hongo Penicillium sclerotiorum UCP 1040 en la producción de biosurfactante usando aceite post fritura y licor de lavado de maíz
Authors: Freitas Elizandro Lima , Lima Sonally de Oliveira , Montero-Rodríguez Dayana , Andrade Rosileide Fontenele da Silva , Campos-Takaki Galba Maria de , Araújo Hélvia Walewska Casullo de
Published: May 2023

El presente trabajo evaluó el potencial biotecnológico del hongo Penicillium sclerotiorum UCP 1040, aislado del suelo del Estado de Pernambuco, para la produción de biosurfactante usando residuos agroindustriales como fuentes alternativas de carbono y nirógen. Las fermentaciones se realizaon durante 144 h, 28ºC y 150 rpm, en medios consistos por diferentes concentraciones de aceite post fritura y licor de lavado de maíz, de acuerdo a un diseño factorial 2 2. Los efectos de los sustratos en la producción del surfactante se evaluaron mediante análisis estadístico, utilizando la tensión superficial como variable de respuesta. Las propiedades emulsionantes y dispersantes del biosurfactante se investigaron mediante el índice de emulsificación (IE24) y el ensayo de dispersión, respectivamente. Los resultados obtenidos mostraron que P. sclerotiorum fue capaz de producir un compuesto surfactativo en presencia de sustratos renovables, observándose la mayor reducción de la tensión superficial (de 72,0 a 42,77 mN/m) en la condición 2 del diseño (medium compuesto por 3% aceite post fritura y 5% liquor de lavado de maíz). Aunque el biosurfactante producido en esta condición no mostró buenas propiedades emulsantes, demostró excelentes propiedades dispersantes, con un área de dispersión de aceite (ADA) de 44,18 cm2. El diagrama de Pareto demostró la influencia significativa de la interacción de los residuos en la producción del biossurfactante, constituyendo sustratos alternativos y de bajo costo, que hacen que el bioproceso sea económico y, por lo tanto, atractivo para diferentes industrias.
El ocaso de la democracia, el fenómeno de las masas y el ejemplo brasileño
Authors: Toledo Claudia , Vieira Nicolás , Barbosa Karine
Published: May 2023

El artículo presenta resultados y conclusiones parciales de investigaciones en desarrollo en la línea de investigación Control Judicial, Sistema de Pesos y Contrapesos, Principio de Separación de Poderes, miembro del Grupo de Investigación Judicial Actual – Activismo o Actitud: judicialización de la política y politización del poder judicial, certificado por el CNPq, bajo la coordinación de la Prof. Cláudia Toledo. Apuntando a la Estudio de la Control judicial de los actos y omisiones de los otros poderes públicos en cumplimiento del sistema de pesos y contrapesos vigente en un Estado Democrático de Derecho, este trabajo se centró en la crisis del modelo liberal de democracia que se vive actualmente en diferentes países, incluido Brasil, en particular, desde la elección de Jair Bolsonaro como presidente en 2018. Las conclusiones alcanzadas en este estudio siguen como premisas las investigaciones actualmente en curso en el referido Grupo de Investigación.
El valor de la “F de significación” de esta regresión espacial que analiza los conflictos socioambientales en la Bahía de Sepetiba (RJ)
Authors: Soares Débora Gaspar , Antelo Fernanda do Socorro Ferreira Senra , Mendes Gianne Cristina dos Reis Ferreira
Published: May 2023

Este artículo discute los conflictos socioambientales de la Bahía de Sepetiba (RJ) y reflexiona con mayor profundidad sobre el contexto social, histórico y geográfico de esta oscura realidad del territorio de Santa Cruz, ubicado en parte de la Zona Oeste de Río de Janeiro. En este sentido, el objetivo de este trabajo y a partir de la licencia ambiental del Complejo Industrial-Siderúrgico-Portuario de Companhia Siderúrgica do Atlântico (ThyssenKrupp - CSA), analizó el índice IGNI de los municipios de Río de Janeiro en función de la educación del IDHM y el ingreso del IDHM utilizando el modelo de regresión espacial CAR (Auto Regresivo Condicional) para relacionar este conflicto socioambiental de la Bahía de Sepetiba (RJ) con sus posibles generadores, con sus impactos y sus daños a la salud. Finalmente, el resultado de este estudio fue que el método del Modelo de Regresión Automática Condicional (CAR) fue relevante para este estudio porque su uso permitió la investigación y adecuación del modelo de regresión para analizar el grado de influencia del índice IGINI. Esposible observar el poder de influencia que algunos municipios ejercen sobre sus vecinos, ya sea positiva o negativamente a favor del índice IGINI estudiado, contemplando la contextualización histórica del área de vulnerabilidad geográfica de este conflicto socioambiental de la Bahía de Sepetiba (RJ).
Adaptación y validación del instrumento “las competencias y la tutoría en la práctica” (COMYUPRACH)
Authors: Tlalpan-Hernández Rosa María Teresa , Nájera-Gutiérrez Gudelia , Flores-Merlo Marcela , Amador-Gómez Rosario , López-García Cesar
Published: May 2023

Las demandas del mercado profesional así como la movilidad social, requieren que los egresados de las licenciaturas sean competentes, capaces de enfrentarse a nuevas situaciones laborales, como el de ser innovadores, creativos, resolutivos generadores de nuevas ideas, competentes y que sean capaces de resolver lo que la sociedad demande de ellos, el objetivo del estudio fue adaptar y validar el instrumento “Las competencias y la Tutoría en la Práctica” (COMYUPRACH) en el estudiante de la licenciatura de enfermería. El proceso de validación del instrumento consistió en un estudio documental e instrumental sobre el tema, se tomó en cuenta las competencias generales del Proyecto Tunning para enfermería las cuales fueron las Competencias Instrumentales, Interpersonales y Sistemáticas,análisis de expertos y aplicación de prueba piloto la cual se realizó a 28 estudiantes que se encontraban cursando las asignaturas de fundamental I y fundamental II. El análisis de expertos arrojo un indice de válidez de contenido de 8.91. El coeficiente de la consistencia interna el Alfa de Cronbach fue de .926 lo que se concluye que el instrumento posee válidez de constructo y es altamente confiable. El instrumento “Las Competencias y la Tutoría en la Práctica” (COMYUPRACH) es confiable para la aplicación en la práctica clínica de los estudiantes de licenciatura en enfermería en las diferentes instituciones de salud, para conocer las diferentes competencias que desarrollan y así conocer si los recursos humanos que se estan formado son necesarios y responden a las necesidades de la sociedad.
Internacionalización en los estudios de posgrado: nuevas miradas, adaptaciones y reinterpretaciones en el período de Pandemia COVID-19, 2020 – 2021 en el Doctorado en Educación Superior de la Facultad de Ciencias Sociales del Programa de Intercambio IESLA - Brasil y Universidad de Palermo - Argentina
Authors: Feitosa Celma Lopes , Marques Kelly Soraya , Oliveira Maria Clécia Bento de
Published: May 2023

Este estudio tiene como objetivo presentar una lectura crítica y dialógica, posibilitando reflexiones de carácter sociológico sobre la estructura sistémica de la sociedad, como la movilidad social y la cooperación internacional, la conducta ideológica y sus normas, instituciones destacando las universidades en el período de pandemia de COVID - 19, 2020 -2021. En cuanto a los impactos y confrontaciones educativas en la educación superior en este mismo período, destacamos las adaptaciones, adecuaciones y reajustes de la educación presencial a la virtual, con base en los marcos normativos de emergencia de la CONEAU – Comisión Nacional de Evaluación y Acreditación Universitaria (Argentina ), MEC – Ministerio de Educación y CAPES - Coordinación para el perfeccionamiento del personal de enseñanza superior (Brasil). Se relata la experiencia del curso de Doctorado en Educación Superior de la Facultad de Ciencias Sociales del IESLA-Brasil y del programa de intercambio Universidad de Palermo-Argentina, destacando todo el proceso de adecuación y reestructuración del curso y programas de cara al aprendizaje virtual. escenario con calidad y dando continuidad al rumbo en este atípico período mundial.
Leterasi Akuntansi UMKM Di Kelompok Sadar Wisata Manua Tirta Ponggok Polanharjo Klaten
Authors: Pardi Pardi
Published: May 2023

Leterasi Akuntansi Usaha Mikro Kecil dan Menengah di Kelompok Sadar Wisata Manua Tirta Ponggok Polanharjo Klaten bertujuan untuk memberikan pengetahuan dan pemahaman akuntansi sehingga mampu mengaplikasikan dalam pengelolaan usaha yang berdampak pada pengembangan Usaha Mikro Kecil dan Menengah, sementara itu pengembangan   usaha pada skala mikro untuk memberikan peningkatan pendapatan masyarakat berpendapatan rendah di perdesaan. Kegiatan pengabdian ini dilaksanakan secara offline yang diikuti oleh 22 peserta yang terdiri dari pelaku Usaha Mikro Kecil dan Menengah yang masuk kelompok sadar wisata Manua Tirta di desa Ponggok, Kecamatan Polanharjo, Kabupaten Klaten. Kegiatan pengabdian ini berjalan dengan lancar sesuai perencanaan. Metode yang digunakan dalam kegiatan pengabdian ini adalah dengan melakukan pelatihan dan diskusi yang berkaitan dengan materi akuntansi usaha kecil bagi pelaku Usaha Mikro Kecil dan Menengah. Hasil dari kegiatan ini adalah para peserta mengetahui dan memahami tentang akuntansi Usaha Mikro Kecil dan Menengah pengembangan usaha supaya dapat meningkatkan pendapatan masyarakat.
Pendampingan Penyusunan Laporan Keuangan kelompok Sadar Wisata Bumdes Makmur Desa Bendo, Kapas, Bojonegoro
Authors: Effasa Ahmad Saifurriza , Kuntardina Ari , Rochmayanti Dewi , Sari Ika Puspita , Murtini Murtini
Published: May 2023

Pokdarwis didesa bendo merupakan unsur penggerak mendukung terciptanya lingkungan wisata yang kondusif dan memelihara kebersihan dari lingkungan wisata waduk grobogan yang dibawah unit dari Bumdes Makmur desa Bendo. Dalam pengelolaanya akuntabilitas maupun transparasi keuangan sangat penting dilakukan sehingga dapat memberikan peran dan ruang lingkup kegiatanya secara optimal. Namun berdasarkan hasil observasi pencatatan laporan keuangan yang dilakukan masih bersifat manual dan sederhana, dikarenakan pengelola tidak mempunyai latar belakang pendidikan di bidang kompetensi akuntansi, sehingga belum mampu menyajikan laporan keuangan yang transparan dan akuntabel sesuai dengan standar yang berlaku. Oleh karena itu diperlukan pendampingan terkait penyusunan laporan keuangan. Metode yang dilakukan adalah melakukan survey lapangan, observasi dan analisis solusi, pelaksanaan pendampingan, dan monitoring dan evaluasi. Dan hasilnya adalah pengelola pokdarwis mampu memiliki pengetahuan dasar dalam menganalisis dan mencatat transaksi keuangan, serta menyajikanya dalam laporan keuangan sesuai dengan standar yang ditetapkan.
Evaluasi dan Pelatihan Akuntansi Organisasai Nirlaba Untuk Raudhatul Athfal IRMAS Sukoharjo
Authors: Triyanto Eko , Kurnianingsih Heny , Rachman Arif Nugroho
Published: May 2023

RA IRMAS Sukoharjo adalah Lembaga Pendidikan formal setingkat TK yang termasuk dalam kategori organisasi nirlaba. Pemahaman terhadap akuntansi organisasi nirlaba pada RA IRMAS masing sangat kurang. Oleh karena itu penting adanya evaluasi dan pendampingan terkait pembukuan akuntansi RA IRMAS. Metode yang dilakukan adalah dengan cara mengevaluasi SPI Dan pembukuan yang ada kemudian melakukan pendampingan. Adapun hasil dari pengabdian ini bahwa pihak struktural RA IRMAS Sukoharjo lebih mengerti dan paham mengenai penyusunan pembukuan akuntansi organisasi nirlaba yang baik. Dengan pembukuan akuntansi yang jelas, maka RA IRMAS Sukoharjo dapat terkendali dan berkembang lebih baik
Physiological intracytoplasmic sperm injection does not improve the quality of embryos: A cross-sectional investigation on sibling oocytes
Authors: Le Minh Tam , Nguyen Hiep Tuyet Thi , Van Nguyen Trung , Nguyen Thai Thanh Thi , Dang Hong Nhan Thi , Dang Thuan Cong , Nguyen Quoc Huy Vu
Published: May 2023

Objective: This study aimed to compare the efficacy of physiological intracytoplasmic sperm injection (PICSI) and intracytoplasmic sperm injection (ICSI) in terms of the fertilization rate and embryo quality using sibling oocyte cycles.Methods: This prospective, cross-sectional study collected data from 76 couples who underwent their first cycle at the Hue Center for Reproductive Endocrinology and Infertility, Vietnam, between May 2019 and November 2021. The inclusion criteria were cycles with at least eight oocytes and a sperm concentration of 5×106/mL. Sperm parameters, sperm DNA fragmentation (SDF), fertilization, and the quality of cleavage-stage embryos on day 2 and blastocysts on day 5 were examined.Results: From 76 ICSI cycles, 1,196 metaphase II (MII) oocytes were retrieved, half of which were randomly allocated to either the PICSI (n=592) or ICSI (n=604) treatment group. The results showed no significant difference between the two groups in terms of fertilization (72.80% vs. 75.33%, p=0.32), day 2 cleavage rate (95.13% vs. 96.04%, p=0.51), blastulation rate (52.68% vs. 57.89%), and high-quality blastocyst rate (26.10% vs. 31.13%, p=0.13). However, in cases where SDF was low, 59 cycles consisting of 913 MII oocytes produced a considerably higher blastulation rate with PICSI than with ICSI (50.49% vs. 35.65%, p=0.00). There were no significant differences between the pregnancy outcomes of the PICSI and ICSI embryo groups following embryo transfer.Conclusion: Using variable sperm quality provided no benefit for PICSI versus ICSI in terms of embryo outcomes. When SDF is low, PICSI appears to be able to produce more blastocysts.