bluuebunny/crossref_metadata_2025 huggingface dataset:
GEOPROCESSAMENTO E GESTÃO PÚBLICA: UMA ANÁLISE SOCIOAMBIENTAL DOS CASOS DE DENGUE EM BELÉM (PA)
Authors: Sampaio da Silva Brenda Caroline , Rosa Gabriel Pompeu , De Paula Souza e Guimarães Ricardo José , Tork da Silva Laryssa De Cássia , Catete Clistenes Pamplona
Published: February 2021

A dengue é a arbovirose mais difundida no mundo com alto potencial de desenvolvimento em regiões de clima tropical. Este trabalho objetivou analisar a distribuição espacial e ambiental dos casos de dengue, nos anos de 2015 e 2016 em Belém (PA). Para isso, foi realizada uma pesquisa documental, bibliográfica, de cunho exploratório, descritivo e abordagem quantitativa. Neste contexto, a área de estudo correspondeu ao município de Belém, estado do Pará. Vale destacar que os dados secundários foram obtidos do SINAN, do Ministério da Saúde, IBGE e USGS; já os dados primários foram adquiridos mediante a realização do georreferenciamento em lote pelo Batchcoordinatese Google Maps. Os dados foram depurados no Microsoft Excel e importados para o Banco de Dados Geográfico (BDGeo), em seguida, os mapas foram produzidos no software ArcGis Desktop 10.3. Foram georreferenciados 1440 casos de dengue. Notou-se que esses casos são pertinentes as áreas urbanizadas e estão intimamente relacionados à precariedade das habitações e do saneamento ambiental existente em Belém. Através de análise espacial (técnica de Kernel), observou-se que as aglomerações dos casos estão evidenciadas nos distritos DABEL, DAGUA e DASAC. A população mais atingida foi referente às faixas de escolaridade com níveis mais elevados e pertencentes ao sexo feminino. Dessa forma, a aplicação das ferramentas de geoprocessamento foram fundamentais para as análises associadas à epidemiologia da dengue no município, pois foi possível identificar as áreas de risco e realizar a distribuição espacial do agravo, permitindo assim mecanismos de controle e monitoramento da doença.
GOVERNANÇA DA GESTÃO DE RISCO DE DESASTRES: MÉTODO DE ANÁLISE COM BASE NA REFLEXÃO TEÓRICO-CONCEITUAL
Authors: Jansen Giane Roberta , Vieira Rafaela , Henkes Jairo Afonso
Published: February 2021

O aumento mundial no número de registros de desastres refletiu internacionalmente nos marcos de Yokohama (1994), Hyogo (2005-2014) e Sendai (2015-2030). Considerando que a discussão da temática é considerada relativamente recente, mas cujos movimentos e resultados são contínuos em sua reflexão teórico-conceitual; o estudo objetiva desenvolver um método de análise da governança da gestão de risco de desastres. Trata-se de uma pesquisa teórico-metodológica de abordagem sistêmica. O estudo aponta que a capacidade da gestão de risco de desastres pode ser analisada com base na compreensão da estrutura da rede de cooperação entre seus diferentes stakeholders; dos diferentes níveis espaciais envolvidos nesta rede e do grau de consolidação das políticas de GRD.
MAPEAMENTO E AVALIAÇÃO DE IMPACTO AMBIENTAL UTILIZANDO AERONAVE REMOTAMENTE PILOTADA NO PARQUE NACIONAL SERRA DE ITABAIANA (BRASIL)
Authors: Rodrigues Jônatas Lemos , Fernandes Milton Marques , Fernandes Márcia Rodrigues de Moura
Published: February 2021

Com recursos insuficientes o Parque Nacional Serra de Itabaiana (PARNASI), localizado no estado de Sergipe (Região Nordeste do Brasil) apresenta dificuldades de gestão e os maiores problemas estão associados à situação fundiária em que diversos estudos científicos indicam impactos que comprometem seus ecossistemas. O objetivo desse estudo foi realizar um mapeamento de baixo custo sobre o uso e cobertura da terra na área do PARNASI e avaliar o nível de impacto ambiental uma vez que os recursos escassos, a extensão da área do parque e sua topografia representam um desafio para a gestão. Utilizou-se da técnica de fotogrametria aérea com imagens de alta resolução coletadas por meio de um pequeno drone e utilizando um modelo multicritério para a análise de dados, em que as variáveis foram hierarquizadas e ponderadas atribuindo-se um peso para cada classe de uso e cobertura da terra mapeada. Os resultados demonstram que 82,2% da área mapeada possui níveis de declividade considerados entre muito fraco a médio e não possui níveis significativos considerados alto e muito alto de declividade. Todavia, a área em que o nível de impacto foi considerado alto e muito alto está representada pela soma das classes Cultivo e Desmatamento (7,51%), e representa uma área de 5.944 ha.  Concluiu-se que a integração das tecnologias utilizadas pode aumentar a escala temporal e espacial sobre o estudo dos padrões e processos de uso e cobertura da terra e pode ser considerada uma estratégia de conservação eficaz para o monitoramento de áreas protegidas.
ANTAGONISMO E CONTRASTE NA APLICAÇÃO DO ORDENAMENTO JURÍDICO COM RELAÇÃO A DELIMITAÇÃO DE TOPOS DE MORRO
Authors: Teixeira Schier Daiane , Rafaeli Lemos Mayara , Henkes Jairo Afonso , Becegato Valter Antonio
Published: February 2021

O novo Código Florestal Brasileiro, Lei 12.651/2012, alterou alguns parâmetros que definem as áreas de preservação permanente (APPs), em especial, a classe de topo de morros. Em decorrência dessa nova definição tais áreas passaram a ser extintas, já que dificilmente são encontradas na natureza, concomitantemente a variação altimétrica maior que 100 e declividade média maior que 25º. Além disso, tem-se dificuldades quanto a interpretação da referida legislação, que apresenta conceitos subjetivamente. Sabendo que a redução do nível de exigência preservacionista dessas áreas pode vir a trazer graves prejuízos ao patrimônio biológico e genético brasileiro, buscou-se realizar uma pesquisa bibliográfica quanto aos métodos utilizados para delimitação de APPs em topos de morro, correlacionando dados obtidos em outras pesquisas e verificando quais obtiveram êxito ou não. A metodologia que mais vem ganhando espaço na delimitação dessas áreas diz respeito às geotecnologias, as quais são viáveis principalmente por dispenderem de pouco tempo para a realização do mapeamento, o que agiliza o processo de fiscalização.
Effect of whitening mouth rinses on the chemical and physical properties of a nanofilled composite
Authors: Kepler Laura Carolina , Rodrigues Ana Paula Morona , Dall Agnol Mauro Antonio , Rodrigues-Junior Sinval Adalberto
Published: February 2021

Aim: This study analyzed the effect of whitening mouth rinses on water sorption (WS), solubility (SL), color change, and surface roughness of a nanofilled composite. Whitening perceptibility and acceptability (WID) were also studied. Methods: Forty specimens of Filtek Z350XT, shade EA2 were produced and randomly distributed (n=8) to AS – artificial saliva (control); LWE – Listerine Whitening Extreme; CLW – Colgate Luminous White; LCM – Listerine Cool Mint; and CP – Colgate Plax. They were immersed in the mouth rinses 2x/day, for one minute, during 28 days. The color was assessed using an Easyshade spectrophotometer (CIE-L*a*b* system). Surface roughness (Ra-μm) was measured with three parallel measures, using an RP-200 roughness meter. The WS and SL (μg/mm-3) were analyzed based on the ISO 4049 recommendations. The data were analyzed using one- and two-way ANOVA/Tukey tests (α=0.05). Results: Surface roughness significantly increased after immersion in AS and LCM, with no significant differences between the groups either before or after immersion. The ΔE* was not significantly different between the groups. All substances produced a ΔWID higher than the 50%:50% perceptibility and acceptability thresholds. The WS and SL were not significantly affected by the mouth rinses. Conclusion: Whitening mouth rinses did not affect WS, SL, surface roughness, and color stability of a nanofilled composite, regardless of the presence of ethanol in the composition.
Are stress and symptoms of depression associated with halitosis?
Authors: Chisini Luiz Alexandre , Gonzales Cademartori Mariana , Collares Kauê , Costa Francine dos Santos , Azevedo Marina , Demarco Flávio Fernando , Correa Marcos Britto
Published: February 2021

Mood disorders such as stress and depression can promote alterations of several hormones Aim: The present study aimed to evaluate if symptoms of depression and stress are associated with halitosis. The hypothesis is that halitosis is associated with stress and depression symptoms. Methods: All university students’ entrants in the Federal University of Pelotas (UFPel) were invited to participate. Self-reported halitosis was measured using a visual analog scale. Students were also asked about the presence of halitosis perceived by close individuals. The stress level was measured using a modified version of the Perceived Stress Scale and symptoms of depression were screened by Patient Health Questionnaire-2. Poisson Regression Models were performed. Results: Of a total of 2,058 students who participated in the study, only 16% of them have reported not having any degree of halitosis and 17.6% were informed of closed individuals having halitosis. After adjustments, stress and depression symptoms remained associated with halitosis selfreported. Individuals from the higher stressed quartile presented higher scores of halitosis (RR 1.37 CI95% [1.24–1.53]). Students who presented depressive symptoms showed higher scores of self-perceived halitosis (RR 1.20 CI95% [1.10–1.32]). When the association of stress and halitosis reported by close individuals was tested, symptoms of depression lost the association in the adjusted model, while individuals from the highest quartile from stress remained associated (PR 1.36 CI95% [1.02–1.81]). Conclusion: Halitosis was associated with stress even after control for oral health and socioeconomic variables.
Prevalence of tumours of the maxillomandibular complex diagnosed in a reference center in Brazil
Authors: Valente Pires Alessandra Laís Pinho , Nascimento Izana Santos Borges , Assis Ana Letícia  Marques de Souza , Hassam Sheinaz Farias , Farias Jener Gonçalves de
Published: February 2021

Tumors of the maxillomandibular complex are a heterogeneous group of lesions with a wide spectrum of clinical and histopathological characteristics. Aim: To evaluate the prevalence of odontogenic and non-odontogenic tumors associated with maxillary bones in a Reference Center for Oral Lesions. Methods: A cross-sectional study based on the medical records of a Reference Center for Oral Lesions at the State University of Feira de Santana, from 2006 to 2018. The data was initially analyzed in a descriptive manner. For bivariate analysis, Pearson’s chi-square test was applied. The level of significance was set at 5%, where p≤ 0.05 is considered significant. Results: The prevalence of tumors was 2.27%. The average age of the individuals was 22.2 (± 15.1) years, the majority being up to 39 years (79.59%) and female (69.40%). A statistically significant difference was observed in relation to age (p = 0.00), as well as regarding the location of tumors in the anterior or posterior region (p = 0.02). Odontogenic tumors were benign, with odontoma being most frequent (46.90%), followed by ameloblastoma (16.30%). As for the non-odontogenic, neurofibroma (4.10%) and osteoma (4.10%) were the most common across the benign, while osteosarcoma accounted for 6.10% of cases. Conclusion: Odontogenic tumors were the most frequent in women, with age up to 39 years, odontoma being most common in the posterior region of the mandible. Among nonodontogenic tumors, central neurofibroma and osteoma were the most common. Osteosarcoma was more frequent in men over 40 years old and in the mandible region.
Diabetes, Hypertension, Obesity, and Smoking as Risk Factors for Chronic Kidney Disease in Productive Age
Authors: Sinusi Rahmawati , Hargono Arief
Published: February 2021

Background: Based on the Indonesia basic health research report in 2018, the prevalence of chronic kidney disease (CKD) in the productive age group in Indonesia had increased from the previous year, to 1.97%. This condition can cause various complications that contribute to the high morbidity, which affects quality of life and productivity, so risk factors for CKD need to be understood to prevent the occurrence of the disease. Purpose: This study aimed to analyze the risk factors associated with CKD in the Indonesian productive-age population. Method: This study used data sourced from Indonesian Family Life Survey 5 (IFLS-5) with a cross-sectional research design. The study population was composed of all Indonesian residents who were respondents of IFLS-5. The research sample was made up of respondents aged 15–64 for whom complete information was available. The sample size was 29,120 respondents. The variables analyzed in this study were diabetes, hypertension, obesity, smoking, and CKD. The analysis method used was the chi-square test. Results: Bivariate analysis showed a significant relationship between CKD and diabetes (p = 0.01; prevalence ratio [PR] = 2.71; 95% CI = 1.74–4.22), hypertension (p = 0.01; PR = 2.62; 95% CI = 2.08–3.30), obesity (p = 0.01; PR = 1.67; 95% CI = 1.25–2.23), and smoking (p = 0.01; PR = 1.43; 95% CI = 1.17–1.75) in the productive age group in Indonesia. Conclusion: Diabetes, hypertension, obesity, and smoking have a significant relationship with CKD in the productive age group in Indonesia.
İSMAİL TUNALI'NIN SANAT ELEŞTİRİSİ ANLAYIŞI
Authors: GEZGİN Ümit
Published: February 2021

Makalede; sanat ve sanat eleştirisi alanında ortaya koyduğu çalışmalar üzerine yargı-yorum geliştirilmeye çalışıldı. İsmail Tunalı, sanat eleştirisi alanında birçok kitap yazmış, teorik alanda sanatın düşünsel gelişimi için büyük gayretler göstermiş bir düşünürdür.
Prof. Dr. İsmail Tunalı, plastik sanatlar kültürü alanında getirdiği yorum ve değerlendirmeler, kattığı kültürel zenginliklerle önemli açılımlar, bilgi donanımsal aydınlatmalar sağlamış ve hem ortaya koyduğu literatürle, hem de geliştirdiği yorumlar ve eleştirilerle derinlikli, özgün bilgilendirmeler sağlamıştır.
CUMHURİYET MODERNLEŞMESİNİN PERİFERİDEKİ TANIKLARI; GİRESUN KAMU YAPILARI
Authors: KARAİBRAHİMOĞLU Selin , DEMİRKAN Özgür
Published: February 2021

Cumhuriyet modernleşmesi, modern ve ulusal bir devlet sisteminin temsili olarak; Anadolu’nun sahip olduğu içsel bileşenlerin, toplumsal yapının, topoğrafik özelliklerin ve en önemlisi zamansal bileşenlerin belirlediği yeniden inşa sürecinin ideolojik temelini oluşturur. Bu kapsamda merkezin ardından sınırlı bir içerikle ve ardıl zamanlarda periferi kentlerinde; farklı anlamlarla varlık bulan, yerellikleri ile harmanladıkları kendi modern oluşlarını ortaya koyan bu uygulamalar, Cumhuriyet ideolojisinin evrimini anlatırken modern mimarlık ve planlama tarihinin de tanıklığını yapmışlardır. Bugün, Anadolu’nun periferisine bakarak merkezi anlamak ya da zamansal ardıllıkları bağlamında tersine bir okuma gerçekleştirmek mümkündür. Bu nedenlerle çalışmanın amacı; homojen, ölçülebilir, genellenebilir kabuller içeren merkez odaklı mimarlık yazımının dışında; çelişkileri, karmaşıklıkları, bilinmezleri ile periferideki yerel odaklı modernleşme deneyimini açığa çıkarmak ve modern mimarlık tarihine katkı sağlamaktır. Anadolu’nun periferisindeki Giresun çalışmanın odağına yerleştirilmiş, 1930- 1980 aralığında inşa edilmiş kamu yapıları ve kentsel düzenlemeler Cumhuriyet modernleşmesinin uygulamaları olarak merkez-periferi paradigması ekseninde değerlendirilmiştir. Bu kapsamla kentte halen varlığını sürdüren yapılara odaklanan çalışmada yapılar; modernleşme sürecini tanımlayan olguların yereldeki temsili üzerinden “ideoloji”, “ideal” ve “kalkınma” olarak belirlenen üç kavramla ilişkili gruplanmış, her grubun benzeşen ya da farklılaşan yönleri dönemsel gelişmeler bağlamında irdelenmiştir. Böylece, merkezin periferiye müdahalesi ve periferi kentlerde izlenen modernleşmenin yerel açılımları; Giresun odağında tartışılabilmiş, kendine modern mimarlık tarihi araştırmalarında yer bulamayan bir kent ve yapıları literatüre kazandırılmıştır.
International Security, Strategic Stability and Information Technologies
Authors:   Primakov National Research Institute of World Economy and International Relations, Russian Academy of Sciences (IMEMO), 23, Profsoyuznaya Str., Moscow, 117997, Russian Federation, Romashkina N. , Markov A. ,   Primakov National Research Institute of World Economy and International Relations, Russian Academy of Sciences (IMEMO), 23, Profsoyuznaya Str., Moscow, 117997, Russian Federation, Stefanovich D. ,   Primakov National Research Institute of World Economy and International Relations, Russian Academy of Sciences (IMEMO), 23, Profsoyuznaya Str., Moscow, 117997, Russian Federation
Published: February 2021

The monograph is devoted to topical issues of international security and strategic stability in the context of accelerated development of information and communication technologies. It justifies the importance of ensuring international information security. The monograph examines the possibility of establishing an ITarms control regime under the UN auspices. Different aspects of regulation of software security systems and of the use of supercomputers in the context of the international information security are examined. The impact of information and communication technologies on strategic stability is analyzed. This monograph is addressed to specialists in the field of information and communication technologies and international security, university lecturers, students and graduate students of universities, as well as a wide range of readers.
PENINGKATAN LITERASI MASYARAKAT TERHADAP ORANG DENGAN SKIZOFRENIA (ODS) DI DESA SINDUMARTANI YOGYAKARTA
Authors:   Fakultas Ekonomi, Universitas Islam Indonesia, Rafik Abdur , Febrianti Yosi , Lusiyana Novyan
Published: February 2021

The Results of Basic Health Research from Ministry of Health of the Republic in Indonesia places Yogyakarta as one of the provinces with the highest prevalence of schizophrenia after Bali, and Sindumartani Village is one of the villages with the highest number of People with Schizophrenia (PWS) in Yogyakarta. The presence of negative stigma from the community and even family members of PWS is one of the crucial obstacles to the PWS healing process. The stigma and low social awareness towards PWS are thought to hamper the process of enriching ODS’ social cognition. Our activities try to provide counseling and education to non-PWS members groups and PWS’ family members so that they can be well literated for schizophrenia with all the characteristics and handling. In addition to the counseling, we educate them by forming a healthy mental alert cadre within the community. In the period after the implementation of the activities, the results showed an increase in communities’ literacy in schizophrenia and a decrease in the prevalence of recurrence in PWS. To improve the sustainability of results, further therapy such as vocational therapy is recommended.
OPTIMALISASI FUNGSI BUMDES MELALUI INOVASI DAN MANAJEMEN ORGANISASI SEBAGAI UPAYA MENINGKATKAN KEMANDIRIAN DESA
Authors:   Fakultas Ekonomi, Universitas Islam Indonesia, Wibisono Arif Fajar
Published: February 2021

Pendirian BUMDes merupakan salah satu upaya pemerintah untuk menjadikan lembaga ekonomi sekaligus lembaga sosial yang bertujuan untuk meningkatkan kesejahteraan masyarakat Desa dan memupuk modal sosial masyarakat Desa. Namun hingga saat ini masih banyak fungsi dan peran BUMDes yang belum dirasakan manfaatnya oleh masyarakat. Hal ini diakibatkan berbagai macam kondisi, diantaranya masih rendahnya pengetahuan pengelolaan organisasi dan sedikitnya inovasi usaha yang dikembangkan oleh BUMDes. Dikarenakan keadaaan tersebut maka BUMDes belum mampu menjadi sumber ekonomi bagi organisasinya apalagi bagi masyarakat secara keseluruhan. Masih banyak usaha BUMDes yang belum menghasilkan keuntungan bahkan masih harus di subsidi oleh pemerintah Desa. Maka tidak heran jika masih banyak BUMDes yang hanya tinggal nama saja tidak memiliki kegiatan ekonomi sama sekali. Tidak terkecuali 8 BUMDes dari 16 Desa di Kecamatan Ngablak Jawa Tengah, dari jumlah tersebut hanya 4 yang memiliki kegiatan ekonomi namun belum optimal menghasilkan keuntungan bagi organisasi maupun bagi masyarakat. Dengan adanya kondisi tersebut maka pengabdian ini dilaksanakan dengan berbagai strategi agar fungsi dan peran BUMDes yang ada di kecamatan Ngablak menjadi lebih optimal dan harapannya dapat memberikan manfaat bagi organisasi dan masyarakat secara keseluruhan. Strategi yang digunakan yaitu penguatan pengelola organisasi, manajemen organisasi dan pengembangan inovasi
PEMBERDAYAAN PEREMPUAN/IBU TUNGGAL MELALUI PELATIHAN PEMBUATAN PRODUK INDUSTRI RUMAH TANGGA HALAL DAN SEHAT SEBAGAI USAHA PENINGKATAN SELF EFIKASI DIRI DALAM BERWIRAUSAHA
Authors:   Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Islam Indonesia, Fitri Noor , Sulistyarini Rr. Indahria , Windarti Yuni
Published: February 2021

Pengabdian ini fokus kepada pemberdayaan perempuan/ibu tunggal melalu pelatihan pembuatann produk industri rumah tangga yang halal dan sehat sebagai usaha peningkatan self efikasi diri dalam berwira usaha. Produk industri rumah tangga yang dikembangkan adalah sosis dan keju. Program pemberdayaan yang dilakukan meliputi (1) Support Group Therapy dan Motivasi Edukasi Perempuan dalam Ikhtiar dan Tawakkal; (2) Pangan Halal Sehat dan Komposisi Kimiawi dalam Makanan; (3) pembuatan sosis; dan (4) pembuatan keju. Peserta pelatihan adalah perempuan/Ibu Tunggal maupun Ibu rumah tangga yang menjadi tulang punggung keluarga. Mitra kegiatan ini adalah Yayasan Rumpun Nurani, yaitu sebuah lembaga nirlaba yang berfokus pada pengembangan, penguatan Sumber Daya Manusia melalui bidang pendidikan, sosial, dakwah dan ekonomi. Sinergi Pengabdi UII dan mitra Yayasan Rumpun Nurani bertujuan untuk pemberdayaan perempuan/Ibu Tunggal menjadi ibu tangguh, peningkatan keterampilan usaha, serta penyediaan sosis dan keju halal, sehat dan bergisi bagi umat. Program ini dapat direkomendasikan menjadi program wilayah pemerintah Yogyakarta maupun nasional dalam pemberdayaan ibu tunggal menjadi ibu yang tangguh dan produktif dalam rangka penguatan ketahanan keluarga bangsa Indonesia.
PEMODELAN TEMPAT PEMBERIAN ASI EKSLUSIF DI LINGKUNGAN PEKERJAAN
Authors:   Fakultas Kedokteran,  Universitas Sriwijaya, Jaji Jaji , Idriasari Antarini , Fikri M Zainal
Published: February 2021

The low coverage of breastfeeding is a threat to the growth and development of children. Some of the things that hinder exclusive breastfeeding include the low level of knowledge of mothers and families about the benefits of breastfeeding, and how to breastfeed properly. In addition, the lack of lactation counseling services and support from health workers, socio-cultural factors, the incessant marketing of formula milk, and factors of working mothers. Some things that can facilitate breastfeeding for working mothers are support from the office environment, support from superiors, coworkers, flexible work schedules, rest periods, positive work colleagues 'attitudes towards breastfeeding, working mothers' attitudes. While some things that can hinder breastfeeding are psychological stress caused by tight work time and discomfort at the time of breastfeeding. Lack of time and location of breastfeeding rooms is also recognized as one of the obstacles in breastfeeding during working hours. The counseling and assistance activities of exclusive breastfeeding are a real form of triad prevention that must be carried out by health workers, especially nurses at the community Health centers. Expressing milk is one of the solutions to keep breastfeeding at work. 5 facilities that can be provided by the workplace to keep breastfeeding, namely: a breast milk pump, a room for milking or a room for breastfeeding, rest periods for milking or for breastfeeding, there is a refrigerator for storing milk and there is support from the workplace. Mothers are committed to giving exclusive breastfeeding to their children, and for workplace institutions to provide opportunities for mothers who have children aged 0-6 months, continue to give their milk by relaxing time for the management of dairy milk.
Approaches to Monitor ATP Levels in Living Cells: Where Do We Stand?
Authors: Ley-Ngardigal Seyta , Bertolin Giulia
Published: February 2021

ATP is the most universal and essential energy molecule in the eukaryotic cell. This is due to its ability to store energy in form of high energy phosphate bonds, which are extremely stable and readily usable by the cell. This energy is key for a variety of biological functions such as cell growth and division, metabolism, signalling, and for the turnover of biomolecules. Understanding how ATP is produced and hydrolysed with a spatiotemporal resolution is necessary to understand its functions both in physiological and pathological contexts. In this review, we will first describe the ATP synthase, the main molecular motor for ATP production in mitochondria. Second, we will review the biochemical assays currently available to estimate ATP quantities in cells, and we will compare their readouts, strengths and weaknesses. Then, we will explore the palette of genetically-encoded biosensors designed for microscope-based approaches and show how their spatiotemporal resolution opened up the possibility to follow ATP levels and production in living cells. Finally, we will comment on how ATP monitoring is used in preclinical practices, and to what extent genetically-encoded sensors could be used as a promising tool to elucidate pathologies in which ATP is implicated.
Tracheal Aspirate miRNA Signatures in Preterm Infants with Severe Bronchopulmonary Dysplasia
Authors: Siddaiah Roopa , Oji-Mmuo Christiana , Montes Deborah , Fuentes Nathalie , Donnelly Ann , Spear Debra , Silveyra Patricia
Published: February 2021

Bronchopulmonary dysplasia (BPD) is a form of chronic lung disease that develops in neonates as a consequence of preterm birth and arrested fetal lung development. The incidence of BPD remains on the rise, as a result of increasing survival of extremely preterm infants. Severe BPD contributes to significant health care costs and is associated with prolonged hospitalizations, respiratory infections, and neurodevelopmental deficits. In this study, we aimed to detect novel biomarkers of severe BPD. We collected tracheal aspirates (TA) from preterm babies with mild/moderate (n = 8) and severe (n = 17) BPD, and we profiled the expression of 1048 miRNAs using a PCR array. Associations with biological pathways were determined with the Ingenuity Pathway Analysis (IPA) software. We found 31 miRNAs differentially expressed between the two disease groups (2-fold change, FDR < 0.05). Of these, 4 miRNAs displayed significantly higher expression levels, and 27 miRNAs had significantly lower expression levels in the severe BPD vs. the mild/moderate BPD group. IPA identified cell signaling and inflammation pathways associated with miRNA signatures. We conclude that TAs of extreme premature infants contain miRNA signatures associated with severe BPD. These signatures may serve as biomarkers of disease severity in infants with BPD.
Compliance with NPIs and Possible Deleterious Effects on Mitigation of an Epidemic Outbreak
Authors: Barbarossa Maria Vittoria , Fuhrmann Jan
Published: February 2021

The first attempt to control and mitigate an epidemic outbreak caused by a previously unknown virus occurs primarily via non-pharmaceutical interventions (NPIs). In case of the SARS-CoV-2 virus, which since the early days of 2020 caused the COVID-19 pandemic, NPIs aimed at reducing transmission enabling contacts between individuals. The effectiveness of contact reduction measures directly correlates with the number of individuals adhering to such measures. Here, we illustrate by means of a very simple compartmental model how partial noncompliance with NPIs can prevent these from stopping the spread of an epidemic.
The Atmospheric Aerosol Over Western Greece - Six Years of Aerosol Observations at the Navarino Environmental Observatory
Authors: Hansson Hans-Christen , Tunved Peter , Krejci Radovan , Freud Eyal , Kalivitis Nikos , Hennig Tabea , Maneas Giorgos , Gerasopoulos Evangelos
Published: February 2021

The Eastern Mediterranean is a highly populated area with air quality problems as well where climate change already is noticed by higher temperatures and changing precipitation pattern. The anthropogenic aerosol affects health and changing concentra-tions and properties of the atmospheric aerosol affect radiation balance and clouds. Continuous long-term observations are essential in assessing the influence of anthro-pogenic aerosols on climate and health. We present 6 years of observations from Navarino Environmental Observatory (NEO), a new station located at the south west tip of Pelo-ponnese, Greece. The two sites at NEO, were evaluated to show the influence of the local meteorology but also to assess the general background aerosol possible. It was found that the background aerosol was originated from aged European aerosols and was strongly influenced by biomass burning, fossil fuel combustion, and industry. When subsiding into the boundary layer, local sources contributed in the air masses moving south. Mesoscale meteorology determined the diurnal variation of aerosol properties such as mass and number by means of typical sea breeze circulation, giving rise to pronounced morning and evening peaks in pollutant levels. While synoptic scale meteorology, mainly large-scale air mass transport and precipitation, strongly influenced the season-ality of the aerosol properties.
Socio-Economic Patterns of COVID-19 During the Pandemic in Italy
Authors: Mateo-Urdiales Alberto , Fabiani Massimo , Rosano Aldo , Vescio Maria Fenicia , Del Manso Martina , Bella Antonino , Riccardo Flavia , Pezzotti Patrizio , Regidor Enrique , Andrianou Xanthi
Published: February 2021

Objective: To investigate the association between deprivation and COVID-19 outcomes in Italy during pre-lockdown, lockdown and post-lockdown periods.Design: Retrospective cohort study.Setting: All municipalities in Italy with less than 50,000 population.Participants: 38,534,169 citizens and 222,875 COVID-19 cases reported to the Italian epidemiological surveillance were assigned to quintiles based on the deprivation index of their municipality of residence.Interventions: The COVID-19 pandemic during pre-lockdown, lockdown and post-lockdown from the 20th of February to the 15th of October of 2020.Main outcome measures: Multilevel negative binomial regression models, adjusting for age, sex, population-density and region of residence were conducted to evaluate the association between deprivation and COVID-19 incidence, case-hospitalisation rate and case-fatality. The association measure was the rate ratio.Results: During pre-lockdown, lockdown and post-lockdown, the incidence rate ratios (IRR) with 95% confidence interval (CI) in the most deprived quintile with respect to the least deprived quintile were 1.17 (95% CI 0.98 to 1.41), 1.14 (1.03 to 1.27) and 1.47 (1.32 to 1.63), respectively. In those three periods, the case-hospitalization IRR were 0.68 (0.51 to 0.92), 0.89 (0.72 to 1.11) and 0.99 (0.81 to 1.22) and the case-fatality IRR were 0.92 (0.75 to 1.13), 0.95 (0.85 to 1.07) and 1.02 (0.73 to 1.41), respectively.Conclusions: During lockdown and post-lockdown, but not during pre-lockdown, a higher incidence of cases was observed in the most deprived municipalities compared with the least deprived ones. No differences in case-hospitalisation and case-fatality according to deprivation were observed in any period under study.
Bio-Gasoline and Bio-Kerosene Production by Fractional Distillation of Pyrolysis Bio-Oil Açaí Seeds
Authors: Rocha de Castro Douglas Alberto , da Silva Ribeiro Haroldo Jorge , Hamoy Guerreiro Lauro Henrique , Pinto Bernar Lucas , S. J. Bremer Sami Jonatan , da Silva Almeida Hélio , Costa Santos Marcelo , Duvoisin Jr. Sergio , Pizarro Borges Luiz Eduardo , Teixeira Machado Nélio
Published: February 2021

The bio-oil obtained by pyrolysis of Açaí (Euterpe oleracea Mart.) seeds at 450 ºC, 1.0 atmosphere, in technical scale, submitted to fractional distillation to produce biofuels-like fractions. The distillation of bio-oil carried out in a laboratory distillation column (Vigreux) of 30 cm. The physical-chemistry properties (density, kinematic viscosity, acid value and refractive index) determined by official methods. The chemical functions present in distillation fractions determined by FT-IR and the chemical composition by GC-MS. The distillation of bio-oil yielded gasoline, light kerosene, and kerosene-like fuel fractions of 16.16, 19.56, and 41.89% (wt.), respectively. All the physical-chemistry properties (density, kinematic viscosity, acid value and refractive index) increase with boiling temperature. The gasoline-like fraction is composed by 64.0% (area.) hydrocarbons and 36.0% (area.) oxygenates, while light kerosene-like fraction by 66.67% (area.) hydrocarbons and 33.33% (area.) oxygenates, and kerosene-like fraction by 19.87% (area.) hydrocarbons and 81.13% (area.) oxygenates.
Stability and Stabilization of Ecosystem for Epidemic Virus Transmission Under Neumann Boundary Value Via Impulse Control
Authors: Rao Ruofeng
Published: February 2021

In this paper, by using the variational method, a sufficient condition for the unique existence of the stationary solution of the reaction-diffusion ecosystem is obtained, which directly leads to the global asymptotic stability of the unique equilibrium point. Besides, employing impulse control technique derives the globally exponential stability criterion of delayed feedback ecosystem.And numerical examples illuminate the effectiveness of impulse control, which has a certain enlightening effect on the actual epidemic prevention work . That is, in the face of the epidemic situation, taking a certain frequency of positive and effective epidemic prevention measures is conducive to the stability and control of the epidemic situation. particularly, the newly-obtained theorems quantifies this feasible step.
Sub-Millisecond Integrated Mix-and-Inject Microfluidic Sample Delivery Devices
Authors: Hejazian Majid , Balaur Eugeniu , Abbey Brian
Published: February 2021

Microfluidic devices which integrate both rapid mixing and liquid jetting for sample delivery are an emerging solution for studying molecular dynamics via X-ray diffraction. Here we use finite element modelling to investigate the efficiency and time-resolution achievable using microfluidic mixers within the parameter range required for producing stable liquid jets. Three-dimensional simulations, validated by experimental data, are used to determine the velocity and concentration distribution within these devices. The results show that by adopting a serpentine geometry, it is possible to induce chaotic mixing, which effectively reduces the time required to achieve a homogeneous mixture for sample delivery. Further, we investigate the effect of flow rate and the mixer microchannel size on the mixing efficiency and minimum time required for complete mixing of the two solutions whilst maintaining a stable jet. In general, we find that the smaller the cross-sectional area of the mixer microchannel, the shorter the time needed to achieve homogeneous mixing for a given flow rate. The results of these simulations will form the basis for optimised designs enabling the study of molecular dynamics occurring on millisecond timescales using integrated mix-and-inject microfluidic devices.
Generalized Geometry for Second Order Tangent Groups & Affine Configuration Complexes
Authors: Iqbal Azhar , Ali Gohar , Khan Javed
Published: February 2021

In this work, generalized geometry of second-order tangent groups and affine configuration complexes is proposed. Initially, geometry for higher weights n=4 and weights n=5 is presented through some interesting and suitable homomorphisms, finally, this geometry is extended and generalized for any weight n.
Evaluating the Stressors Impacting Rescued Reptilian Wildlife
Authors: Pahuja Harsh , Narayan Edward
Published: February 2021

Direct and indirect anthropogenic factors play a massive role in driving wildlife species towards extinction. Longitudinal retrospective studies identify key ‘factors’ responsible for the decline in numbers of wildlife, however, lack the reasoning behind the events leading to mortality. The overarching aim of this study was to categorize these ‘factors’ into different stressor categories faced by reptiles to understand its impact on an individual, and to compare how each stressor category influences the survival of an individual. The results from this study indicated that almost half of the number of reptiles being hospitalized were due to exposure to preliminary stressors such as lawn mowing incidents and pet attack. Primary and secondary admissions were fairly equal in number, however the mortality rate for secondary admissions was drastically high (~80%). The discussion integrates species’ ecology and stress physiology which can prove to have multi-faceted benefits across the fields of ecology and animal welfare. Ecologists can use the results from this study to comprehend species’ activity patterns to better plan reptilian conservation programs, whereas, for wildlife clinicians and rehabilitators, assignment of stressor categories could be a beneficial tool for bolstering the welfare monitoring program for small native reptiles in clinical settings.
Analisis penanganan konflik antar organisasi kemasyarakatan di Kabupaten Karawang
Authors: Susanto Erwin , Maftuh Bunyamin , Malihah Elly , Budimansyah Dasim
Published: February 2021

Kebebasan untuk berpendapat dan berserikat merupakan landasan fundamental demokrasi dan dilindungi oleh negara. Dalam perkembangannya, kebebasan berserikat tersebut termanifestasikan pada pembentukan kelompok dan organisasi kemasyarakatan. Fungsi positif dari terbentuknya organisasi kemasyarakatan ini yaitu terjaminnya kebebasan individu, namun di sisi lain berdampak negatif bagi ketertiban masyarakat dengan dalih kebebasan bertindak, berpendapat dan berserikat dilindungi oleh negara. Tujuan penelitian ini adalah untuk melihat apakah faktor penyebab terjadinya konflik antar lembaga swadaya masyarakat di Karawang dan bagaimana kebijakan pemerintah daerah dalam menangani konflik tersebut. Penelitian ini dilakukan di Kabupaten Karawang, dengan menggunakan pendekatan kualitatif dengan metode studi kepustakaan. Hasil penelitian menunjukkan bahwa pemicu konflik yang paling dominan adalah faktor ekonomi, yakni perebutan limbah yang bernilai ekonomis. Konflik yang terjadi sifatnya destruktif, memberikan dampak yang tidak baik ke masyarakat. Penanganan konflik yang telah dilakukan dari pihak terkait adalah tindakan tegas seperti menjatuhkan pidana kepada pelaku kerusuhan. Kemudian Pemerintah Kabupaten Karawang mengeluarkan Peraturan Daerah tentang Ormas sebagai upaya pencegahan konflik di masa yang akan datang.
Editorial
Authors: Japar Muhammad , Abdillah Fauzi
Published: February 2021

Editorial
Desain dan Uji Coba E-Book Berbasis POE (Prediction-Observation-Explanation) Pada Materi Laju Reaksi
Authors: Afrianis Neti , Permata Bunda Intan
Published: February 2021

This research was instigated by the importance of learning facility technology based for students on Chemistry Subject.  It was aimed at knowing the validity and practicality of media that was designed. This research was conducted to the eleventh-grade students of MIPA 6 at State Senior High School 1 Pekanbaru in the Academic Year 2019/2020, and they were 12.  It was Research and Development with Borg and Gall modified model.  The techniques of collecting the data were observation, interview, questionnaire, and documentation.  The final product was in the form of instructional media that was valid.  POE (Prediction, Observation and Explanation) based Electronic Book on Reaction Rate lesson had been tested valid by experts of media and material with 90.13% mean percentage (very valid), and practical by 2 Chemistry subject teachers and 12 students with 91.41% mean percentage (very valid).  Based on the result, it could be concluded that POE based Electronic Book on Reaction Rate lesson was valid and practical, so the next phase could be tested.

Keywords: Chemistry Instructional Model, Electronic Book, POE (Prediction, Observation and Explanation), Reaction Rate.
Calculation of the Capacity for the Operation of a Mini-Energy Complex Based on an Inde-pendently Operating Asynchronous Generator
Authors: Konstantinova S. V. , Kapustinskii A. Yu. , Yaroshevich T. M.
Published: February 2021

The article present the analysis of the operation of the mini-energy complex (MEC) based on alternative energy sources. An asynchronous generator (AG) was taken as energy source. The IEC operates independently with standard power parameters without the use of a frequency converter. To operate independently, AG needs a source of reactive excitation current. Based on the calculations carried out and the results obtained with the use of the experimental facility,the operating conditions of the MEC with standard parameters of electricity under varying load have been analyzed. A characteristic feature of the autonomous MEC is the commensurate capacity of the generating device and consumers. Therefore, any power consumer on/off leads both to significant changes of local electric system parameters and affects the operation of the generator itself. In this article, the main attention is paid to the influence of three-phase motor load on stable AG operation. When the MEC operates independently, reliable self-excitation of the asynchronous generator and the start-up of consumers whose power is commensurate with the generating unit must be ensured. It is also necessary to ensure the maintenance of voltage stability, the possibility of automatic operation of the generating unit, and the preservation of its integrity in emergency modes. Thus, for stable MEC-based AG operation the nature of the load should be taken take into account, the parameters of the of the local grid should be known as well as the exact availability of consumers and their characteristics, and also equivalent circuit parameters of asynchronous motors. In addition, it is necessary to accurately calculate the capacity when changing the parameters of the electrical system, so as not to lose the self-excitation of the asynchronous generator, which is equivalent to disconnecting the entire load of the generator and causes a sharp increase in speed. To solve these problems, it is necessary to create a high-speed MEC control system.
INFLUÊNCIA DO SILÍCIO NO CULTIVO E NO PÓS-COLHEITA DA CEBOLA (Allium Cepa)
Authors: Natália Laurindo  , Rafael da Rosa Couto
Published: February 2021

A cebola (Allium cepa) é a terceira hortaliça com maior importância no Brasil. No entanto, enfrenta problemas relacionados á sua qualidade durante o período de armazenamento, podendo haver perdas de até 45%. Nesse sentido, a aplicação de silício (Si) pode aumentar a produtividade e o tempo de armazenamento da cebola. A aplicação de Si vem sendo incentivada na cultura da cebola por empresas e associações, devido a processos fisiológicos benéficos que causa em algumas hortaliças. No entanto, pouco se sabe sobre as vantagens dessa estratégia para a cultura da cebola. Desta forma, este trabalho objetivou avaliar a eficiência de aplicações de Si na cultura da cebola, verificando o efeito de diferentes doses, fontes e formas de aplicação de Si na produtividade e armazenamento da cultua em sistema deplantio convencional. O trabalho foi realizado no município de Ituporanga, e foram testados 5 doses de silício: 1-200 g m-2 de Si, proveniente da casca de arroz carbonizada; 2- 200 g m-2 de Si proveniente de dióxido de silício via solo; 3- 2,52 g L-1 de Si proveniente de dióxido de silício via foliar; 4- 1,68 g L-1 de Si proveniente de dióxido de silício via foliar; 5-Testemunha sem aplicação de Si, sobre duas cultivares de cebola, Super Precoce e Bola Precoce, totalizando 10 tratamentos, com 3 repetições. Os tratamentos foliares foram aplicados a cada vinte e um dias, iniciando uma semana após o transplantio até a data do estalo da cebola, totalizando 5 aplicações. Já os tratamentos via solo foram realizados em uma única aplicação, uma semana após o transplantio. Após a colheita os bulbos foram armazenados por 180 diasem ambiente não controlado, pesadas a cada 30 dias em balança digital, avaliando as perdas por desidratação, apodrecimento e brotação. Análises de pH, sólidos solúveis totais e acidez total titulável foram realizados logo após a colheita, e após os 180 dias de armazenamento. Os resultados demonstraram não haver diferença significativa entre os tratamentos, evidenciando que a nutrição da cebola com este nutriente nestas dosagens não interfere na qualidade póscolheita da cebola. Portanto, para uma melhor acurácia dos dados encontrados, o experimento em questão está sendo repetido, nas mesmas condições de pesquisa.
OBTENÇÃO DE NOVAS CULTIVARES DE PESSEGUEIRO A PARTIR DA HIBRIDAÇÃO ADAPTADAS AS CONDIÇÕES DO ALTO VALE DO ITAJAÍ-SC
Authors: Guilherme F. de Souza  , Gislaine Novak  , Cláudio Keske  , Gilmar S. Rocha
Published: February 2021

O Alto Vale do Itajaí apresenta características climáticas propícias para a produção comercial de frutíferas temperadas como o pessegueiro, sendo porém necessário a procura de cultivares adaptadas as condições da região. Este trabalho visou obter novas cultivares de pessegueiro, avaliar a efetividade de hibridação entre as cultivares e verificar o percentual de germinação das sementes obtidas.O experimento foi realizado em pomar experimental, na sede doInstituto Federal Catarinense – Campus Rio do Sul. Foram utilizados para cruzamento as cultivares de pessegueiro Douradão, Aurora e Fascínio, DellaNona e BRS Citrino. Foram realizados cerca de 100 cruzamentos para cada dupla de cultivares.Pólen colhido de flores recém-abertas dos parentais masculinos foi utilizado na polinização de flores dos parentais femininos; estas últimas foram emasculadas antes da antese. A emasculação foi realizada em botões florais próximo da abertura (estádio de balão), eliminando-se cuidadosamente as pétalas e anteras com auxílio de pinça e bisturi, e evitando-se o contato com o estigma. Em todos os casos a polinização foi imediatamente após a emasculação, estando o estigma receptivo(úmido). As flores polinizadas foram deixadas abertas e os frutos que vingaram foram fechados com saco de papel manteiga cristal, permanecendo fechadas até a colheita. Os frutos foram colhidos após quatro a cinco meses e as sementes serão cuidadosamente separadas, retirando-se as mal formadas. Após foi realizada a quebra de dormência das amêndoas, sendo colocadas envoltas em papel toalha, umedecidas e depositadas em Câmara fria a 50 C por 40 dias. Após foram semeadas em vasos contendo substrato comercial para verificar o percentual de germinação. Estas plantas serão avaliadas posteriormente. Foram acompanhados o vingamento da polinização e posterior percentual número de frutos resultantes. Tivemos o vingamento de 29 frutos polinizados, resultando no final em apenas sete frutos devido a perdas por animais silvestres. Estão sendo aguardados a germinação das sementes e repetido as hibridações em novo ciclo da cultura.
AVALIAÇÕES EDUCACIONAIS
Authors: Ayessa Regina de Borba  , Jaqueline Samara Reis  , Letícia Santos da Silva Saraiva  , Luana Tayná Borba dos Santos  , Araceli Gonçalves
Published: February 2021

O presente relato de experiência, expõe atividades avaliativas realizadas com duasturmas de ensino médio e uma de ensino fundamental II, entre setembro de 2018 ejunho de 2019, no Programa Residência Pedagógica. Tem como objetivoproblematizar/discutir o termo “avaliação” e suas aplicações, por meio das atividadesaqui propostas. Os educandos evidenciam seus saberes e comprovam suaaprendizagem com foco no raciocínio lógico, dando autonomia ao aluno para escolherum método ou artifício para apresentação do mesmo. Através disso, afirmamos queas metodologias diferenciadas agregam ao aluno e ao professor, sem deixar decaminhar unidas aos métodos tradicionais.