bluuebunny/crossref_metadata_2025 huggingface dataset:
A Randomized, Controlled Trial Comparing the Total Enteroscopy Rate and Diagnostic Efficacy of Novel Motorized Spiral Enteroscopy and Single-Balloon Enteroscopy in Patients With Small-Bowel Disorders: The Motor Trial (NCT 05548140)
Authors: Rughwani Hardik , Singh Aniruddha Pratap , Ramchandani Mohan , Jagtap Nitin , Pal Partha , Inavolu Pradev , Reddy P. Manohar , Januszewicz Wladyslaw , Sekaran Anuradha , Nabi Zaheer , Patel Rajendra , Lakhtakia Sundeep , Banerjee Rupa , Memon Sana Fathima , Balram Putta , Darishetty Santosh , Rao Guduru Venkat , Reddy D. Nageshwar
Published: July 2023

INTRODUCTION:

Device-assisted enteroscopy has revolutionized the management of small-bowel disorders (SBD). No study to date has compared both novel motorized spiral enteroscopy (NMSE) and single-balloon enteroscopy (SBE) as a randomized controlled trial. Hence, this study was planned to include patients having SBD with the primary aim to compare the total enteroscopy rate (TER).

METHODS:

This study was conducted at the Asian Institute of Gastroenterology (AIG Hospitals), Hyderabad, India, from September 20, 2022, to December 15, 2022. All consecutive patients, older than 18 years with suspected SBD, and planned for total enteroscopy were screened for inclusion. The primary outcome was to compare the TER, and secondary outcomes were to compare the technical success, time taken to reach the depth of maximal insertion, withdrawal time, total procedure time, diagnostic yield, therapeutic success, and adverse events (AE).

RESULTS:

Seventy-two patients of the 110 patients screened were randomized in either NMSE (n = 35) or SBE (n = 37) group. The most common indication for the procedures was obscure gastrointestinal bleed (48%), others being unexplained abdominal pain with indeterminate radiologic findings (32%) and chronic diarrhea (20%). In NMSE group, the TER was 71.4%, whereas in the SBE group, it was 10.8% (P < 0.0001). The total procedure time (minutes) was much lesser with NMSE (58.17 ± 21.5 minutes) vs SBE (114.2 ± 33.5 minutes) (P < 0.0001). The diagnostic yield of NMSE (80%) was comparatively higher than SBE (62.1%) (P = 0.096). Minor AE (grade I) were observed in both the groups: NMSE 8.5% (3/35) and SBE 5.4% (2/37).

DISCUSSION:

This randomized controlled trial shows that with NMSE higher TER can be achieved in shorter duration with minimal AE, compared with SBE.
Digital Ageism: Emerging Challenges and Best Practices of Age-Friendly Digital Urban Governance
Authors: Kolotouchkina Olga , Viñarás-Abad Monica , Mañas-Viniegra Luis
Published: July 2023

The ageing of urban populations poses serious challenges for policymakers and urban planners alike. While the number of people over 65 is increasing in urban areas, the digital transition in cities raises concerns about the persisting digital divide facing older citizens, as well as the digital inequality and ageism inherent to most digital domains. As ageing in place and place attachment play a significant role in the social engagement and well-being of older people, the purpose of this research is to shed light on the novel approaches taken by local governments to foster active participation among senior residents in the digital public sphere. Using semi-structured interviews with public officials from three age-friendly cities in Spain, we have explored innovative urban projects for digital inclusion, active ageing, and autonomy for older people. The findings of the study reveal the importance of coordinated multi-stakeholder initiatives in promoting digital literacy and overcoming barriers rooted in ageism in the digital world. True representation of older people in local governments, the promotion of co-creation initiatives led by seniors, and the standardisation of universal design and accessibility are some of the key contributions made by Spanish cities in their transition toward places that are digitally inclusive and age-friendly.
La gerencia de operaciones en las empresas de la costa norte colombiana 1900-1950: una perspectiva historiográfica
Authors: González-Díaz Jaime-Eduardo , Brito-Carrillo Clara-Judith , Peroza-Daza José-David
Published: July 2023

This work tries to characterize the operations management in the companies of the Colombian north coast between years 1900-1950. Methodologically, the study relied on secondary sources constituted by the life histories of the industrialists studied; data collection was carried out using research files, analysis rubrics and lexicometric tables (text mining); and for the data analysis, a triangulation was applied between content analysis, discourse analysis, and thematic analysis. The management of operations in the studied entrepreneurs was characterized by the development of products, the design of the production process, and the implementation of technology and machinery to carry out manufacturing; to a lesser extent due to plant distribution and installed capacity; and few allusions to quality and workmanship; This is congruent with the industrial administration of the time, which emphasized improving the tools and working methods.
La competencia de los comités en el mecanismo de queja. Una mirada desde los estados latinoamericanos
Authors: González-Serrano Andrés , Castro-Londoño Katherine
Published: July 2023

The main aim in this article is to describe the decisions on admisibility issued by the United Nations Comittees on cases related to Latinamerican States that have recognized its competence. The results are obtained through qualitative, basic and legal investigation, using the deductive and inductive analythic method, centering its analysis on the international practice performed by the Comittees, concluding that the admisibility has been centered in the competence on the person, the time, the issue and the place; using International Law principles such as locus standi, irretroactivity, voluntarism and jurisdiction, found within the clause and/or facultative disposition of the mandatory jurisdiction for each State Party. Decisions that incorporate homogeneity in the reason of its decision without putting at risk the adjective aspect of the International Law, that is to say, that a legal and segmented pluralism is evident, as well as a crossed, coherent and shared practice in the general matters, without holding contradiction o incompatibility, that would promote an absolute autonomy or risk on the fragmentation of the International Law.
Perspectivas investigativas sobre Lectura Literaria y Mediación Lectora en Contextos Escolares
Authors: Restrepo Álvarez María Camia , Alzate Alzate Natalia Andrea , Londoño Vásquez David Alberto
Published: July 2023

Objective: this review article is focused on the theoretical stakes that have been developed in publications from Spanish speaking countries regarding literary reading and reading mediation in school contexts, aiming to the comprehension of the topic from the relationship that it establishes with the National reading plans and the strategies to motivate the literary reading in the school. Method: for this, a qualitative bibliographic review was done from the perspective of hermeneutical analysis, with a descriptive scope. The consolidated corpus comes from research reports type publications available in Scielo, Scopus, and Ebsco, and Master and doctoral theses published in institutional repositories between 2014 and 2020. The texts found were systematized and analyzed by the means of a previously validated matrix. Conclusions and discussion:  the approaches and perspectives found put the emphasis on the importance of the reading of literature in school contexts, but at the same time they draw attention to the danger of reducing the strategies and mediations only to academic and curricular aspects.
Measurements of heat transfer coefficients from supercritical fluid flowing in vertical mini channels with constant wall temperature
Authors: JADDOA Ameer Abed
Published: July 2023

Currently, efficient heat transmission for compact electronic elements is an essential matter. It needs a heat sink with a liquid cooling scheme that meets these demands as much as feasible. The dimensions of 50.8 × 40.6 × 5.5 mm were adopted for features of heat transfer as well as
the fluid flow of supercritical CO2 in the heat sink in this study. The adopted pressures, tem-peratures, and mass velocity ranges were 7.5 to 12 MPa, 35 to 50oC, and 100 to 500 Kg/m2s,
respectively, wherein the CO2 cooled under these conditions. The factors of heat transfer, the pressure at levels of local as well as medium degree were determined under these conditions.
The medium temperature of CO2 in the adjacent significant point area increased, the pressure
decreased and the medium temperature movement factor augmented dramatically. It was also noted that the medium temperature movement factor peaked at the pseudo-critical tempera-ture. However, the maximum temperature movement factor declined increased pressure. Fur-thermore, in contrast to the pressure factor, it was revealed that mass velocity and temperature movement factor had a direct relationship. Using the obtained data, a novel correlation mech-
anism for limited convection of super-critical CO2 in regular multi-port micro tubes based on chilling conditions was constructed using the obtained coefficients in this study.
The Effectiveness of Different Types of Massages on Sleep Quality in Hemodialysis Patients: A Literature Study
Authors: Freeska Dwi Marta Ollyvia , Wahyu Mashfufa Erma , Setyowati Lilis , . Nur Aini , Mazidah Nur
Published: July 2023

Hemodialysis can cause disturbance in sleep. Sleep disorders cause immune system disorders and decreased sleep quality. Low sleep quality leads to poor quality of life resulting in premature death and negative impacts on the individual’s immune response which can lead to the development of cardiovascular diseases, which is the leading cause of death in patients with kidney disease. This study aimed to identify and describe the effectiveness of different types of massages in improving the sleep quality of hemodialysis patients. This was a literature study. We examined a journal that focused on massage therapy in patients undergoing hemodialysis. The observed variable was the sleep quality of hemodialysis patients. Data were analyzed using the qualitative descriptive analysis method. The results showed that hand massage therapy, foot massage therapy and back massage therapy were effective in improving the sleep quality of hemodialysis patients. However, massage therapy in the form of acupressure is less effective in improving sleep quality. Based on the results, aromatherapy massage therapy on the feet was the most effective. The most influential type of massage was massage using aromatherapy. Massages of the hands, feet, and back also affected the sleep of hemodialysis patients but only slightly affects the quality of sleep.
Keywords: massage, hemodialysis, accupressure, aromatherapy
The Role of Religiosity on Hijab Buying Intention on Premium Hijab of Muslim Consumers in Indonesia
Authors: Farid Najib Moh , Fauziah Tia , Djatnika Tjetjep , Saefulloh Dedy
Published: July 2023

Hijab is defined as a veil or a cover, which usually has cultural connotations in a country where the population is predominantly Muslim. Hijab serves to cover Muslim women’s hair with modest clothing. Hijab products are varied, not only used as a cover but also can increase the confidence of Muslim women because hijab fashion does not have to be left behind by non-hijab fashion. Therefore, the purpose of this study was to determine the role of religiosity on the purchase intention of Muslim consumers in Indonesia. The research method used is qualitative research with semi-structured in-depth interviews. The results showed that the interaction of religiosity in using hijab without being influenced by the premium hijab trend; buying hijab because of its functionality, quality, durability, and costs that reflect its utilitarian value using this premium hijab to experience the latest style experiences and ideas that describe its hedonic values; this premium hijab trend is positive, such as it creates more enthusiasm about wearing the hijab; and indeed liking premium hijab products that reflect their attitude.
Keywords: religiosity, utilitarian value, hedonic value, attitude, hijab premium
Leverage as Intervening Variable of Profitability Post-pandemic (Covid-19)
Authors: . Zulkifli , Saputra Fendi , Zulkifli Muhammad Mohd , Mareta Sigit , Meiwanto Doktoralina Caturida
Published: July 2023

Cement companies in Indonesia support the government’s role in the development of the property sector. However, the Covid-19 pandemic has caused problems in making a profit. Therefore, the main problem of this study is to find out and analyze how profitability affects leverage and market value with the variables price earnings ratio (PER) and price to book value (PBV) as proxies. Second, knowing and analyzing leverage as an intervening variable that relates the effect of profitability to market value. This study uses the documentation analysis method of social research for exploring the theoretical model and empirical results of how profitability affects market value through leverage. The results from various empirical results showed that there is still little research on the ability of leverage as a variable to analyze cement companies listed on the Indonesia Stock Exchange. The results of the study can be expected to contribute to further research and facilitate the government to approach the development of cement companies to encourage the economy. Meanwhile, investors can be informed about the company’s financial performance. This study will provide advanced research guidance and convenience to the companies in providing solutions on how to increase market value by increasing profitability through leverage factors.
Keywords: leverage, market value, profitability, Price Earnings Ratio (PER), Price to Book Value (PBV)
The Effect of Innovation Capability on Market Performance Mediated by External Collaboration on SMEs
Authors: Trio Febriyantoro Mohamad , . Zulkifli , Totok Suyoto Yohanes , Saputra Fendi , Suleman Dede
Published: July 2023

The functions and roles of SMEs in Indonesia are quite numerous both economically, politically, socially, culturally, and securely. Economic-social-political functions and roles, for example, are to increase people’s income, reduce unemployment, poverty, and urbanization flows. This study aims to determine the effect of innovation capability on market performance mediated by external collaboration in Batam SMEs. This study took a sample of 257 respondents, who are managers or owners of SMEs, selected using non-probability sampling method with purposive sampling technique. Data were analyzed using structural equation modeling with partial least square (SEM PLS) approach. The results showed that innovation capability has a significant effect on market performance in SMEs, a significant relationship was observed between innovation capability and external collaboration and between external collaboration on market performance, while the results of the indirect effect showed that external collaboration mediates the relationship between innovation capability and market performance. Suggestions for Batam City SMEs to continue to maximize innovation capabilities and collaborate with various parties to improve market performance.
Keywords: innovation capability, market performance, external collaboration, MSMEs
The Construction of Reality of Media Regarding Ustadz Abdul Somad's Refusal to Enter Singapore
Authors: Rustanta Agustinus , Novianty Soedjarwo Gabriella , Ciputri Berlianda , Alfani Hendra
Published: July 2023

Media shapes the reality perceived by the readers. The issue discussed by the reader is based on how the media report the case. In the case about Ustadz Abdul Somad’s (UAS’s) refusal to enter Singapore was framed differently by two big online news portal: kompas.com and detik.com. Those two media were chosen since they are considered as the big and most-read news portal. The objective of the study is to analyze how the media framed the reality of UAS’s refusal to enter Singapore. The data used in this study were the news published by kompas.com and detik.com during 16-23 May 2022. The news articles were analyzed using the framing analysis method by Pan and Kosicki. This study found out that those two media constructed the reality differently. Kompas.com reported the news in more balance manner in a sense that they took the source both from UAS’s and Singapore’s side. On the other hand, detik.com tended to construct this event on more provocative way: they took the source more on UAS’s side or those who were in the same side of him.
Keywords: constructing reality, framing, news
Why Do Millennials Perform Dysfunctional Behavior Toward an Organization? An Exploratory Study in an Urban Campus
Authors: Naibaho Hastuti , Pitaloka Endang , Totok Suyoto Yohanes
Published: July 2023

Organizations can determine what constitutes dysfunctional behavior in several ways, often by aligning with the shared social values of the local society in which the organization operates. In relation to this, urban environments pose a particular challenge to organizations as its higher degree of diversity compared to rural areas. This exploratory study aims to identify the causes of millennials’ dysfunctional behavior toward organizations. Further, the authors would explore the dimension characteristics of dysfunctional behavior of millennials toward an organization. This study was conducted on an urban campus, with 197 students from various study programs being the respondents. Data collection used open-ended questions distributed through online surveys, followed by focus group discussions to obtain more detailed answers. The results showed that the main targets of the students’ dysfunctional behavior were the college itself, the lecturing staff, and the student-led organizations. The most common reasons for this behavior were disappointment with the goal and being encouraged by other students. The study also found that despite being aware that their actions were deemed unethical by the target, students who committed dysfunctional behaviors did not feel guilty because they believed the target deserved it. The findings of this study are useful for organizational behavior research, particularly in the study of dysfunctional behavior, as it provides empirical data to support that retaliation is one of the antecedents of dysfunctional behavior.
Keywords: revenge behavior, perception of justice, service failure recovery, consumer ethical standards
Intercultural Communication Interaction of Multicultural Society in West Kalimantan Province: Ethnographic Studies
Authors: Fannia Theresi , Johana Kornelia , Awliya Firda , Rismawaty Fitria , Ameri Maya , Lianto Lau Sherly
Published: July 2023

Indonesia has a society with various cultures, due to which there are many ethnic groups with their respective cultural structures and living side by side, which is called multicultural. West Kalimantan Province is one of the regions in Indonesia where multicultural societies live side by side, known as TIDAYU, namely the Tionghua or Chinese, Dayaknese and Melayu or Malays, which are the three largest tribes in West Kalimantan and divided in various places in West Kalimantan. In fact, one of the cities in West Kalimantan, namely Singkawang City was rewarded as the number one most tolerant city in 2018 based on the assessment of the SETARA Institute in collaboration with the Indonesian Ministry of Home Affairs and the Pancasila Ideology Development Agency, and was again ranked number one in 2021. Based on the research results using ethnology-based qualitative method, people in West Kalimantan have been accustomed to cultural diversity from an early age; therefore, the life of the multicultural society in West Kalimantan has a high level of tolerance and intercultural communication in West Kalimantan runs in harmony and respects each other.
Keywords: intercultural communication, interaction, multicultural society, tolerance
The Effect of Brand Awareness, Price Perception and Electronic Word of Mouth (E-WOM) Toward Purchase Intention on Instagram
Authors: Al Faruq Abdullah Muhamad , Desty Febrian Wenny , Hikmah Perkasa Didin , Endah Retno Wuryandari Nur , H. Pangaribuan Yanthy , . Fathihani
Published: July 2023

The most popular social media promotion tool is Instagram. The main factor is that social networking tools enable users to exchange photographs and videos. Additionally, Instagram, which is open to all users and is free, is utilized as a promotional tool, particularly by business people who are trying to establish their own companies. The study aims to determine the effect of the relationship variables that affect purchase intention on Instagram, a social media platform whose popularity is growing at the present time. Primary data were collected through the use of questionnaires sent to a total of 120 respondents located in a variety of cities throughout Indonesia. The data were analyzed using the application of structural positive and equation model (SEM) partial least square (smartPLS 3.0), to determine all of the relationships that exist between the variables of price perception, electronic word of mouth (E-WOM), and brand awareness on purchase intention in the model. The structural model indicates that the model on the buying interest variable can be said to be strong because it has a value that is greater than 0.67. The model of the influence of the independent latent variables (price perception, electronic word of mouth, and brand awareness) on purchase intention has an R-Square value of 0.743, which can be interpreted to mean that the variability of price perception, E-WOM, and brand awareness is 74.3%.
Keywords: price perception, Electronic Word of Mouth (E-WOM), brand awareness, purchase intention
Discourses of Islamic Finance Supporting in Muslim-Friendly Tourism in the New Normal Era (Indonesia Cases)
Authors: Nugroho Lucky , Cetin Gurel , Meiwanto Doktoralina Caturida
Published: July 2023

This conceptual paper analyzes how to develop Muslim-friendly tourism in Indonesia in the new era to increase the number of Muslim tourists. Furthermore, the method is qualitatively based on research questions: (i) What is the government’s strategy to develop Islamic finance in Indonesia? (ii) What is Indonesia’s strategy for developing halal products and services? (iii) What is the strategy for developing Islamic finance to strengthen Muslim-friendly tourism and the creative economy?. The result showed that the existence of Islamic finance and digital ecosystems are very much needed. Therefore, the implication of this conceptual paper is to provide input and information to stakeholders who have the authority to develop Muslim-friendly tourism in Indonesia; and that there is a need for collaboration and synergy between parties, especially in the Islamic finance industry.
Keywords: digital era, finance, halal tourism, post-pandemic, supply chain
Inventing Freedom
Authors: Vanchugov V.V.
Published: July 2023

This work is a brief historical and philosophical essay that allows the author to convey some elements of the mindset formed in the conditions of the transformation of the system – the collapse of one socio-political, civilizational, structure and the formation of a new, intellectual formation in a situation of potentially productive uncertainty.
Slow Fashion and Sustainable Development
Authors: Švajdová Lenka , Mikolašova Jana
Published: July 2023

The garment industry is the second largest polluter of the environment. This sector is characterized by high consumption of water, chemicals, and greenhouse gas emissions. In addition, textiles make up a significant part of municipal production. In this context, the sector of so-called fast fashion, or fast fashion, producing much trend-based clothing, can be particularly problematic. This leads to frequent changes in clothing and the formation of large amounts of textile waste. Therefore, it seems crucial to increase consumer interest in sustainability issues and identify their attitudes to sustainable fashion, thus strengthening the trend of slow fashion. When buying clothes, factors such as quality, brand, price, whether the garment corresponds to current trends, and whether the clothing is made with respect for the environment can be considered. This article aims to identify the importance of the sustainable fashion factor in the consumer's purchasing decisions. The set goal will be achieved using questionnaire survey methods and secondary data analysis. The benefit of this article will be a well-arranged analysis of consumer attitudes towards sustainable fashion with a particular focus on fashion made from recycled materials.
Factors Influencing Entrepreneurs’ Decision-making Concerning SDGs
Authors: Csákné Filep Judit , Szennay Áron
Published: July 2023

Many studies highlight the importance of entrepreneurs in achieving SDGs. While their role is undeniable, mapping their motivations to act according to SDG principles is still in its infancy. The aim of this study is to examine whether the environment surrounding entrepreneurs, their characteristics, and their motivation for starting a business are related to whether SDGs are considered in business decisions. Following a review of the relevant literature, the paper provides empirical evidence for the existence of the hypothesized relationships. The 215-item database of the Hungarian Global Entrepreneurship Monitor Adult Population Survey 2022, restricted to business owner-managers, was used. Chi-Square test and correlation analysis were applied to analyse the relationship between sustainability decisions and the environment, personal characteristics, and start-up motivations of owner-managers. The research shows a relationship between entrepreneurial decisions made with sustainability in mind and the entrepreneur's environment, personality, and motivation to start a business.
Corruption in Public Private Partnerships as a Barrier to Sustainable Development: The Case of Albania
Authors: Teka Soana , Doçi Silvana
Published: July 2023

Public Private Partnerships (PPPs) are one of the forms used by governments to provide a better service for the benefit of the citizens. However, since these projects are of a large scale, the practices of corruption between the state and the private party undermine the value for money, influencing the economic development of the country and the distribution of public funds. In Albania, investments through Public Private Partnerships are highly discussed due to high corruption during the tendering phase, the selection of the winner, but also during the implementation of the project. Almost all PPP investments have been viewed as cases of corruption, and some have resulted in investigations by state authorities. Therefore, this paper aims to represent the potential scope and cost of corruption of PPPs in Albania and how they affect the sustainable development goals. The qualitative analysis reveals that PPPs and corruption have a positive relationship in Albania, implying the urgent need for an effective risk assessment and monitoring plan for PPPs to combat corruption and promote sustainable development.
Interaction Mechanisms and the Performance of Production Enterprises as Social Systems: The Truth of The Human Spirit
Authors: Espejo Raul
Published: July 2023

This contribution goes beyond viewing a system as a black box receiving inputs and producing well defined outputs to an external environment. Its purpose is to explain the complementarity between first and second order cybernetics as well as of economic and sustainable performance. It discusses a black box using the notion of eigenform as developed by Heinz von Foerster (2003) wherein a performing object is understood changing overtime with apparent stability. It contemplates the concepts of structural and linguistic recursions and highlights the values of second-order and ontological cybernetics. The outputs of a black box are fed back to its inputs, possibly in real time, in order to manage its performance towards the often-economic requirements of the system’s external environment, but showing signs of change and adaptation. The transformations the social systems perform are adaptive and change over time, making them non-trivial machines. Beyond producing technological transformations, the complexity of social systems emerges from the operational, moment-to-moment- interactions of its participants. Their outcomes are produced by changes in structure and ethical values, necessary for social sustainability and improved (policy) performance. These changes produce adjustments to the system’s outcomes which are the observer driven mechanism of second-order cybernetics.
International Trade in Waste: The Case of Croatia
Authors: Bašić Maja , Bošnjak Mile , Novak Ivan
Published: July 2023

The aim of this paper is to analyse Croatia’s international trade in waste, in terms of both export and import quantity, value, origin and destination. Data on trade in waste are available from Eurostat for the period 2004-2020. Results show that extra-EU trade in tonnes increased dramatically. Extra-EU export of waste increased for 3475% and extra-EU imports for 433% in the observed period. Intra-EU exports increased for 50% and intra-EU imports increased for 417%, especially after 2013. Intra-EU exports of waste are 3.45 times larger than extraEU exports. Intra-EU imports are on average 1.76 times larger than extra-EU imports. Croatia’s trade in waste is predominantly with other EU member states. In order to make national and global economy resilient to environmental changes and decrease material footprint, generation of waste followed by a trade in waste should be decreased by establishing and following responsible consumption and production patterns.
What are the Young People's Perceptions of the Circular Economy?
Authors: Szigeti Cecilia , Remsei Sándor , Bándy Katalin
Published: July 2023

The circular economy is often seen as a technical issue and focuses on the better organization of work processes. A more accurate and holistic approach to the cycle can help create a better and more inclusive future for all. The circular economy has been linked to several SDGs in previous research, of which our research focuses on SDG 12 (responsible consumption and production). Young people play a key role in achieving a circular future (as an organizing principle of the socio-economic system). In our research, we asked 1,442 university students (most born around 2000) about their awareness, understanding, and participation in the social cycle using a standardized questionnaire. Our research shows that those who consider themselves environmentally conscious are more likely to recycle and collect separately, but it is not clear that they are involved in extending the life of objects (exchange, second market, etc.). Our research found that students don’t use, but are typically unaware of, internet applications that promote circular living.
The Role of Zakat Community Development Program Institutions in Increasing Youth Creativity in Selat Village, West Lombok Regency
Authors: Siswandi Rudi , Fauzan Ahmad , Kurniawansyah Edy , Zubair Muh.
Published: July 2023

This study aims to determine the role of Zakat Community Development program institutions, the creativity of Youth in Selat village, West Lombok district, and the role of Zakat Community Development program institutions in increasing youth creativity in Selat village, West Lombok district. The research method used is a qualitative approach with a survey type. The subject of this research is the head of the program or commonly called a friend of zakat at the Zakat Community Development program institution in Selat village, West Lombok district. Informants in this study were youth and the people of Selat village who had involvement with Zakat Community Development. The informants for this study were determined with certain considerations so that the data from the informants were not arbitrary or commonly referred to as a purposive sampling technique. Data collection was carried out by observation, interview and documentation techniques. Data analysis was carried out using the Miles and Huberman model which took place in four cycles, namely data collection, data reduction, data presentation, and drawing conclusions. The results of the study show that the Zakat Community Development (ZCD) program institution has a very important role in increasing youth creativity in Selat village, West Lombok district, this can be seen from ZCD's commitment in facilitating financing, utilization of natural resources, training and coaching, can be seen also on creative products produced by youth.
Економска евалуација пословања специјалних библиотека: приступи и методолошки оквири
Authors: Дрманац Мирко
Published: July 2023

У времену када технологије вештачке интелигенције попут ChatGPT постају фундаментални концепт развоја семантичког веба, библиотеке се налазе пред све већим изазовом да на глобалном информационом тржишту потврде своју вредност – не само у апстрактном, филозофском смислу већ и у економском. Ово питање посебно се дотиче специјалних библиотека као информационог сервиса који стално мора да доказује свој допринос циљевима организације у оквиру које послује, а чији рад руководиоцима представља основу за планирање развоја и доношење стратешких одлука. У овом раду приказаће се евалуација пословања специјалних библиотека у историјском контексту, као све важнији чинилац не само развоја него и опстанка у националном библиотечко-информационом систему. Биће представљени CBA (cost-benefit analysis), ROI (return on investment) и CV (contingent valuation) као најважније методе које се могу користити за процену успешности специјалних библиотека, са примерима израчунавања.
Az árak emelkedése napjaink élelmiszer piacán
Authors: Szűcs Róbert Sándor , Kovács Krisztina
Published: July 2023

Az elmúlt néhány hónapban hihetetlen gazdasági változásoknak lehettünk tanúi és részesei. Az infláció rég nem látott méreteket öltött, és a közelben dúló háború hatásait mind az árakban, mind a termékhiányban és az ellátási lánc megszakításaiban érezzük. Ráadásul időközben az energiaárak emelkedésével is számolnunk kell, és még a koronavírusnak sem inthetünk búcsút. Ezeknek a változásoknak még messze nincs vége, így felmerül a kérdés, hogyan reagáljunk a vásárlásainkkal, mit változtassunk? Az árak szerepe a szokásosnál is jobban felértékelődni látszik. Kutatásunk fő célja, hogy megállapítsuk, hogyan változtak az élelmiszer-vásárlási szokások az emelkedő árak hatására, és hogyan próbálnak a fogyasztók védekezni a magasabb árak ellen. Ezért kutatásunkban tudatosan olyan személyeket kérdeztünk meg, akik aktívan részt vesznek az élelmiszerek beszerzésében. A lekérdezést online és offline módon is folytattuk. Összesen 1608 válaszadót értünk el. Eredményeink alapján elmondható, hogy a legtöbb háztartást érinti az emelkedő árak hatása. Azonban az élelmiszerárak emelkedése nem minden esetben változtatja meg a vásárlási és fogyasztási szokásokat. Vannak olyanok, akik annak ellenére is ragaszkodnak a régi szokásaikhoz és életmódjukhoz, hogy nem rendelkeznek kiemelkedő anyagi javakkal. Kutatási eredményeink alapján azt látjuk, hogy kezd kialakulni egy olyan alku/akció-vadász, alacsonyabb áron történő beszerzést célzó vásárlási magatartás, amely lehetővé teszi az alkalmazók számára az élelmiszerfogyasztás minőségének és lehetőségének olyan szinten való fenntartását, amelyekhez korábban hozzászoktak.JEL-Kódok: M11, M21, M31, M38, Q18
A csemegekukorica minőségének szerepe az egészséges táplálkozásban
Authors: Demeter Cintia
Published: July 2023

A csemegekukorica, mint egészséges élelmiszer jelentősége világszerte folyamatosan növekszik. A friss fogyasztásra és befőzésre alkalmas szuper csemegekukorica hibridek kutatása és összehasonlító elemzése kiemelt jelentőséggel bír az élelmiszeriparban. Vizsgálataink során három szupercsemegekukorica hibrid karotinoid tartalmát hasonlítottuk össze, hogy adatokat gyűjtsünk az egészséges állapotáról. Tesztjeink új eredménye, hogy a csemegekukorica tartalmazza a legtöbb luteint és zeaxantint. Azt találtuk, hogy a zeaxantin és a lutein mennyiségét a genotípus határozza meg. Megállapítottuk, hogy a karotinoidokat a környezeti feltételek befolyásolják. A lutein, zeaxantin, β-cryptoxanthin, β-karotin koncentrációja nem csökkent a termés növekedésével, ami megerősíti a csemegekukorica hibrid szelekció fontosságát az egészséges táplálkozás szempontjából. Vizsgálataink során a lutein és a zeaxantin mennyisége magasabb volt, mint a béta-kriptoxantin és a béta-karotin mennyisége. A karotin fogyasztása számos pozitív hatással van az emberi szervezetre, csökkentheti a rákos megbetegedések, az érrendszeri megbetegedések, vagy az A-vitamin hiányából adódó farkasvakságot.JEL-Kódok: I1, L15
Morphology and SSR markers-based genetic diversity analysis of sesame varieties released in China
Authors: Wang Zhen , Zhou Fang , Tang Xuehui , Yang Yuanxiao , Zhou Ting , Liu Hongyan
Published: July 2023

Background Sesame, one of the most important oil crops in the world, is rich in sesamol, sesamin, and other antioxidant substances, and can be consumed as oil, food, and vegetable. It has a high nutritional and economic value. To reveal the genetic diversity of the sesame varieties at the molecular and morphological levels, 25 pairs of simple sequence repeat (SSR) primers and 56 biological traits were applied to 101 Chinese sesame varieties released in recent decades, as well as 62 Chinese landraces and 20 alien accessions.
Results The results indicated that a total of 166 SSR bands were detected, with an average of 6.64 per marker; the total alleles were 40.35, with an average of 1.614 per primer pair. Among them, the marker LG141 detected a maximum of 1.85 alleles, and SB393 had a minimum of 1.23 alleles. Shannon’s information index ranged from 0.2732 to 0.6497 with an average value of 0.5292; the polymorphic information index ranged from 0.0859 to 0.6357, with an average value of 0.5254, and the average heterozygosity (He) was 0.3246, suggesting that these sesame accessions have a narrow genetic diversity. The results of the unweighted pair-group method with arithmetic averaging (UPGMA) clustering were consistent with those of the binary principal component analysis, and the 183 sesame lines were categorized into three UPGMA groups. The genetic diversity coefficient of sesame germplasm is generally small, and the genetic relativeness is close. The genetic diversity coefficient of Chinese accessions is not much different from that of foreign resources. Moreover, a DNA fingerprint database of 183 sesame accessions including varieties and germplasm resources was constructed, and a corresponding two-dimensional code was developed.
Conclusion The results of this study provide data reference for the breeding and promotion of new sesame varieties in China, the protection of new variety rights, the inquiry and identification of DNA genetic information of varieties, and the development and utilization of germplasm resources domestically and abroad.
Potential Drugs in COVID-19 Management
Authors: Gasmi Amin , Noor Sadaf , Menzel Alain , Khanyk Nataliia , Semenova Yuliya , Lysiuk Roman , Beley Nataliya , Bolibrukh Liliia , Gasmi Benahmed Asma , Storchylo Olha , Bjørklund Geir
Published: July 2023

The SARS-CoV-2 virus first emerged in China in December 2019 and quickly
spread worldwide. Despite the absence of a vaccination or authorized drug specifically
developed to combat this infection, certain medications recommended for other diseases
have shown potential effectiveness in treating COVID-19, although without definitive
confirmation. This review aims to evaluate the existing literature on the efficacy of these
medications against COVID-19. The review encompasses various potential treatments, including
antiviral medications, anti-malaria and anti-rheumatic drugs, vaccines, corticosteroids,
non-steroidal anti-inflammatory drugs (NSAIDs), antipyretic and analgesic
medicines, antiparasitic drugs, and statins. The analysis also addresses the potential benefits
and drawbacks of these medications, as well as their effects on hypertension and diabetes.
Although these therapies hold promise against COVID-19, further research, including
suitable product production or clinical testing, is needed to establish their therapeutic
efficacy.
Recent Updates on Peptide Molecules in Drug and Vaccine Development
Authors: Sarfaraz Mamoona , Anjum Faiqa , Zahra Duaa , Maqsood Ayesha , Ashfaq Usman Ali
Published: July 2023

Peptides are of great importance in the areas of science because they can act as drug carriers and
their therapeutic effect and their ability to generate an immune response. As culturing of viral agents for drugs
and vaccine development is harmful, therefore, peptide-based drugs and vaccines have achieved great importance.
Large immunoglobulins cannot pass the plasma membrane, so peptides are used to study this interaction
because of their small size. Peptides with substituted amino acid sequences are also stable in blood serum,
which makes them significant for drug development. Peptides with substituted amino acid sequences are stable
in blood serum hence, their stability, small size, easy screening, cost-effectiveness, ease of administration and
particularity (target specificity) make them effective to be used in pharmaceutical companies. Mostly branched
peptides are used for the development of drugs because they are not prone to be degraded by proteolytic enzymes.
In peptide-based vaccines, protein acts as the main constituent from which the main component that
causes the infection is deleted by recombinant DNA technology, and these peptides act as antigens to stimulate
the immune response. Self-assembled peptides have the main role in the delivery of drugs and vaccine
molecules inside the living cells because they may also assemble into nano technological structures to improve
their efficiency. This review focuses on the characteristics of peptides that make them effective to develop
drugs and vaccines. Different peptides like synthetic peptides, antimicrobial peptides, signal peptides, carrier
peptides, and their role against various viral, pathogenic, and microbial diseases and in cosmetics are described
briefly.
Protective Effects of Liriodendrin on Myocardial Infarction-Induced
Fibrosis in Rats via the PI3K/Akt Autophagy Pathway: A Network
Pharmacology Study
Authors: Zhang Ping , Liu Xuanming , Yu Xin , Zhuo Yuzhen , Li Dihua , Yang Lei , Lu Yanmin
Published: July 2023

Background:

Liriodendrin (LIR) has been reported to improve cardiac function in rats
following myocardial infarction. However, its role and mechanism in reparative myocardial fibrosis
remain unclear.

Methods:

In this study, a rat model of myocardial fibrosis was established via left anterior descending
artery ligation and randomly divided into three groups (n = 6 per group): sham-operated,
myocardial infarction, and LIR intervention (100 mg/kg/day) groups. The pharmacological effects
of LIR were assessed using echocardiography, hematoxylin, and eosin (H&E) staining, and Masson
staining. Network pharmacology and bioinformatics were utilized to identify potential mechanisms
of LIR, which were further validated via western blot analysis.

Results:

Our findings demonstrated that LIR improved cardiac function, histology scores, and col
lagen volume fraction. Moreover, LIR downregulated the expression of Beclin-1, LC3-II/LC3-I
while upregulating the expression of p62, indicating LIR-inhibited autophagy in the heart after
myocardial infarction. Further analysis revealed that the PI3K/Akt signaling pathway was significantly
enriched and validated by western blot. This analysis suggested that the ratios of p-
PI3K/PI3K, p-Akt/Akt, and p-mTOR/mTOR were significantly increased.

Conclusion:

LIR may attenuate myocardial infarction-induced fibrosis in rats by inhibiting excessive
myocardial autophagy, with the potential mechanism involving the activation of the
PI3K/Akt/mTOR pathway.
Impact of HLA Class I Antigen, Killer Inhibitory Receptor, and
FCGR3A Genotypes on Breast Cancer Susceptibility and Tumor
Stage
Authors: Canossi Angelica , Aureli Anna , Del Beato Tiziana , Novelli Giorgio , Buonomo Oreste , Rossi Piero , Venditti Adriano , Papola Franco , Sconocchia Giuseppe
Published: July 2023

Background:

The identification in breast cancer (BC) of novel genetic
biomarkers regulating natural killer (NK) cell function, including the HLA, KIR, and
CD16A (FCGR3A), may be still a challenge.

Objective:

We aimed to evaluate whether the combined effect of these polymorphisms
has an impact on BC susceptibility and progression.

Methods:

47 BC Italian patients and healthy individuals (39 females and 66 males/
females) were genotyped by Sanger sequencing (HLA-C exon 2-4 and FCGR3A-
158V/F, 48L/R/H) and PCR-SSP typing (KIR genes).

Results:

HLA-C gene allele analysis showed the group C1, with HLA-C*07:02:01 allele,
to be significantly associated with tumor progression (16.7% vs. 4.0%, p=0.04,
OR=4.867), and instead, group C2, with HLA-C*05:01:01, was protective against
disease susceptibility (0.0% vs. 7.2%, p=0.019, OR=0.087). In addition, we highlighted a
significant reduction of the KIR2DS4ins in BC patients (pcorr.=0.022) and an increased
combined presence of KIR2DL1 and KIR2DS1 genes in advanced BC patients
compared to earlier stages (66.7% vs. 19.2%, p=0.002). The concurrent lack of
KIR2DL2 and KIR2DS4 genes in the presence of HLA-C2 alleles was significantly
associated with increased susceptibility to BC (p=0.012, OR=5.020) or with lymph node
involvement (p=0.008, OR=6.375). Lastly, we identified different combinations of the
FCGR3A-48/158 variants and KIR genes in BC patients compared to controls.

Conclusion:

Our findings suggest that in the development of BC probably exists a
disorder of the NK innate immunity influenced by KIR/HLA-C gene content and
FCGR3A-158 polymorphisms and that the combined analysis of these biomarkers might
help predict genetic risk scores for tailored screening of BC patients in therapy.
Faktor-Faktor yang Mempengaruhi Kinerja Keuangan Pemerintah Daerah di Kabupaten Merangin
Authors: Nurarifah Rina , Afrizal Afrizal , L Tona Aurora
Published: July 2023

Penelitian ini merupakan studi  analisis dan menjelaskan hubungan variabel Akuntabilitas, Transparansi, Sistem Pengendalian, Budaya Organisasi, Kompetensi Aparat dan Pengenolaan Keuangan Daerah yang mempengaruhi Kinerja Keuangan Pemerintah Daerah di Kabupaten Merangin. Metode yang digunakan dalam penelitian ini adalah Survey Explanatory. Kriteria pemilihan sampel adalah aparat pengelola keuangan di intansi pemerintahan di Kabupaten Merangin. Sampel penelitian ini adalah 188 responden. Analisis data dilakukan dengan menggunakan analisis statistik deskriptif berupa  pencapaian kriteria indikator, dan analisis statistic inferensial menggunakan analisis kausalitas Structural Equation Modeling (SEM) berbasis component. Hasil penelitian menunjukkan bahwa Akuntabilitas tidak memiliki pengaruh positif terhadap kinerja keuangan pemerintah daerah. Transparansi tidak memiliki pengaruh positif terhadap kinerja keuangan pemerintah daerah Sistem Pengendalian internal tidak memiliki pengaruh positif terhadap kinerja keuangan pemerintah daerah. Budaya Organisasi tidak memiliki pengaruh positif terhadap kinerja keuangan pemerintah daerah. Kompetensi Aparat memiliki pengaruh positif terhadap kinerja keuangan pemerintah daerah. Pengelolaan Keuangan Daerah berpengaruh positif terhadap kinerja keuangan pemerintah daerah.