bluuebunny/crossref_metadata_2025 huggingface dataset:
Design, Synthesis, Docking and Computational Pharmacokinetic Profiling of New Pyrazolinyl Thiazolinone Biheterocycles as Potent Antimicrobial Agents
Authors: Salian Vinutha Vittala , Narayana Badiadka , Sarojini Balladka Kunhanna , Kodandoor Sharath Chandra , Lobo Anupam Glorious
Published: June 2020

Background:

Development of potential antimicrobial agents is the main aim in the drug
discovery process to overcome the problem of drug resistance. Pyrazolines and thiazolinones are extensively
used as building blocks for the synthesis of diverse and medicinally important compounds.

Methods:

In this present work, a new series of functionalized pyrazolinyl-thiazolinone biheterocycles
is designed and synthesized from N-pyrazolinecarbothioamide. Antimicrobial screening is carried
out in order to discover their potential towards six bacterial and four fungal strains. The zone of
inhibition (ZI in mm) was determined by the disc diffusion method and minimum inhibitory concentration
(MIC in μg/mL) by macro dilution method. The druggability of these new entities is done
through in silico pharmacokinetic profiling using Maestro 2017-1 interface of Schrӧdinger software.

Results and Disscusion:

Compounds 4c and 4e with chloro and iodo substituents on Nphenylacetamide
ring displayed good inhibitory antibacterial activity against the tested bacterial
strains with minimum MIC values when compared to the reference drug tetracycline. Compound 3
with an acetic acid derivative showed high antifungal activity among all the tested derivatives.
Compound 3 not only showed antifungal activity but also qualified druggability test with no violation
of Lipinski rule of five.

Conclusion:

The capability of the synthesized pyrazolinyl-thiazolinone derivatives was performed
to efficiently inhibit the growth of microorganisms against selected bacterial and fungal strains. Further,
these compounds are found to be effectively bound to the active sites of attractive target Escherichia
coli FabH.
Relative Validity and Repeatability of a Zinc-FFQ for Estimating Intakes of Iron, Copper and Selenium in Saudi Adults
Authors: Alsufiani Hadeil M. , Albar Salwa A. , Al-Shehri Aishah D. , Al-Mufti Zain A. , Aldahri Rahaf S. , Omar Ulfat M.
Published: June 2020

Background:

In Saudi Arabia, few studies have addressed iron, selenium and copper intake and status. Most studies on iron have focused on iron deficiency anemia rather than the intake of iron.

Objective:

To assess the relative validity and repeatability of a Zinc-food Frequency Questionnaire (FFQ) for estimating the intakes of iron, copper and selenium in Saudi adults.

Methods:

Ninety-seven Saudi adults participated in this study. All participants completed the FFQ1 and a three-days (3d) Food Record (FR) to assess validity. After one month, the FFQ was administered again (FFQ2) to assess the repeatability.

Results:

Mean intakes of iron, copper and selenium estimated by FFQ1 were significantly higher than those from the 3d FR. Estimated intakes of iron and selenium by both methods were significantly correlated. The Bland-Altman analysis showed that the difference in iron intakes, as measured by the two methods, was similar across the range of intakes while the difference in copper and selenium intakes increased with an increase in the mean intake. No detectable differences were observed between FFQ1 and FFQ2 in estimating iron, copper and selenium intakes. For all nutrients, the intakes from both FFQs were highly correlated.

Conclusion:

The Zinc-FFQ showed reasonable relative validity and repeatability for estimating other micronutrients, such as iron, copper and selenium.
Determination of three Unsaturated Fatty Acids in Pressure Ulcer Rats Using A UPLC-MS/MS Method
Authors: Cai Fuman , Dong Yuwei , Lou Shaosheng , Ma Zeping , Wu Ting , Yang Liuqing , Wen Congcong , Wang Chenxiang
Published: June 2020

Background:

The serum levels of Docosahexaenoic Acid (DHA), Eicosapentaenoic Acid
(EPA) and Arachidonic Acid (AA) under the state of Pressure Ulcers (PUs) are still unclear.

Introduction:

In order to investigate serum levels of DHA, EPA, and AA in PUs rats, an ultraperformance
liquid chromatography-tandem mass spectrometry (UPLC-MS/ MS) method was developed
and validated.

Methods:

Chromatographic separation of DHA, EPA, AA was carried out on a BEH C18 column and
gradient elute consisted of 5 mM ammonium acetate-0.1% formic acid and acetonitrile. Subsequently,
fifty rats were divided into five groups (n=10), four PU groups (A-D) underwent various pressure and
release time protocols, with group E as the control. The concentrations of DHA, EPA, AA from five
groups were determined by using a validated method.

Results:

The results showed there was good linearity for DHA (327.3/283.4), EPA (301.2/257.0), and
AA (303.1/258.9) within 0.05-6.4 μg/mL. In control group, the levels of DHA, AA and EPA were
1.16±0.68, 0.59±0.19 and 0.78±0.21 μg/mL. At the end of modeling, concentrations of DHA, EPA and
AA were increased after long and persistent pressure (>8 h). Especially, the level of DHA was significantly
higher (P<0.01) than that of control group.

Conclusion:

A stable, rA stable, reliable and accurate UPLC-MS/MS for determination of DHA, EPA, AA in
blood was developed. Serum concentrations of DHA, EPA and AA were altered differently after long
and persistent pressure (>8 h), and DHA is a remarkable one.eliable and accurate UPLC-MS/MS for determination of DHA, EPA, AA in blood was developed.
Serum concentrations of DHA, EPA and AA were altered differently after long and persistent pressure (>8 h), and DHA is
a remarkable one.
Metabolic Changes in Mouse Plasma after Acute Diquat Poisoning by UPLC-MS/MS
Authors: Chen Lianguo , Zhong Zuoquan , Liu Jiawen , Wen Congcong , Jin Yongxi , Wang Xianqin
Published: June 2020

Introduction:

Diquat is a fast-acting contact herbicide and plant dehydrating agent. The oral lethal dose 50
(LD50) of diquat in mice is about 125 mg/kg. The purpose of this study is to research the metabolomics in mouse plasma
after acute diquat poisoning.

Method:

These mice were divided into two groups (the control group and acute diquat poisoning group). The control
group was given normal saline by gavage. The acute diquat poisoning group was given 50 mg/kg diquat. UPLC-MS/MS
was used to determinate the small molecule organic acid in mouse plasma.

Results:

Compare to the control group, the L-lysine, Adenine, L-Alanine, L-Valine, Lactic acid, Inosine, Adenosine, LTryptophan, L-Tyrosine, L-Arginine, L-Phenylalanine, L-Methionine, Citric acid, Fructose, L-Glutamine, Malic acid, LAspartic acid and Pyruvic acid increased in the acute diquat poisoning group (p<0.05); while the L-Histidine decreased
(p<0.05).

Conclusion:

The results of metabolites increased or decreased, indicating that acute diquat poisoning induced amino acid
metabolism and energy metabolism perturbations in mice.
Phloretin Ameliorates Acetic Acid Induced Colitis Through Modulation of Immune and Inflammatory Reactions in Rats
Authors: V.S. Arya , S.K. Kanthlal
Published: June 2020

Background:

Adverse effects associated with current therapy for Ulcerative colitis (UC)
over prolonged treatment periods and the high relapse rate limit their use. Incorporating fruits as regular
diet has beneficial role in the management of UC. Phloretin, a dihydrochalcone of apple is reported
for its anti-oxidant and anti-inflammatory effects. Our study aims to evaluate the effectiveness of phloretin
on experimentally induced ulcerative colitis in rats.

Methods:

In vitro study was performed using Raw 264.7 cells stimulated with LPS (1μg/mL) and in
in-vivo study, colitis was induced by intra rectal administration of 4% Acetic acid. Phloretin (50
mg/kg) was given orally for 3 days to Wistar rats after induction for the post-treatment group and 1 day
before induction to the pre-treatment group. Macroscopical, biochemical and histopathological evaluations
were performed to assess the effectiveness.

Results:

A concentration dependent inhibition of MPO and iNOS activity was obtained in LPS stimulated
neutrophil cells. Phloretin exerted ameliorative effect in both pre and post-treatment groups by
restoring plasma ALP and LDH level and reduce inflammatory markers like myeloperoxidase, nitric
oxide and eosinophil peroxidase level as well as downregulates colon ICAM-1 gene in acetic acid induced
ulcerative colitis in rats. Antioxidative potency was confirmed by restoring tissue GSH level.
Phloretin prevents mucosal damage and it was confirmed by histopathological analysis.

Conclusion:

Collectively, our findings provide evidence that phloretin might be useful as a natural
therapeutic agent in the management of UC as well as may pose a promising outcome for future clinical
usage.
Serum Thyroid Peroxidase Antibody Level and Incident Hypertension in Iranian Men: A Suggestion for the Role of Thyroid Autoimmunity
Authors: Tohidi Maryam , Baghbani-Oskouei Aidin , Amouzegar Atieh , Mehran Ladan , Azizi Fereidoun , Hadaegh Farzad
Published: June 2020

Background:

Dysfunction of the thyroid gland has profound effects on the cardiovascular
system.

Objective:

We aimed to explore the relation of serum thyroid peroxidase antibody (TPO-Ab), as a
marker of thyroid autoimmunity with incident hypertension among a euthyroid population.

Methods:

A total of 3681 participants (1647 men) entered the study. Multivariate Cox proportional
hazard models were conducted to estimate the association between TPO-Ab and incident hypertension.

Results:

The mean age (standard deviation) of the participants was 37.5 (12.8) years. During a median
follow-up of 12.2 years, 511 men and 519 women developed hypertension. The multivariable hazard
ratios (HRs) and related 95% confidence intervals (CIs) of 1-unit increase in natural logarithm (ln) of
TPO-Ab for incident hypertension were 1.09 (1.00-1.19), 1.03 (0.97-1.10), and 1.05 (1.00-1.11) for
men, women, and total population, respectively. Moreover, considering the TPO-Ab status as a categorical
variable (i.e. TPO-Ab positive or TPO-Ab negative), the multivariate-adjusted HRs (95% CIs)
of TPO-Ab positivity for incident hypertension, were 1.33 (0.95-1.85), 1.12 (0.86-1.45) and 1.19 (0.97-
1.46) for men, women, and total population, respectively.

Conclusion:

Elevated serum TPO-Ab level can contribute to the development of hypertension among
euthyroid men during a long follow-up; suggesting a role for thyroid autoimmunity.
Spotlight on Circadian Genes and Colorectal Cancer Crosstalk
Authors: Rajendran Senthilkumar , Barbon Silvia , Pucciarelli Salvatore
Published: June 2020

Mammalian physiology is regulated by circadian clock through oscillating feedback loops
controlling cellular processes and behaviors. Recent findings have led to an interesting connection
between circadian disruption and colorectal cancer progression and incidence through controlling the
hallmarks of cancer, namely cell cycle, cell metabolism and cell death. Deeper understanding of the
circadian mechanisms that define the colorectal cancer pathophysiology is the need of the hour to define
a chronotherapy for improving colorectal cancer patient survival. This review identifies the key
areas in which circadian genes interact with cellular pathways to modify the outcome with respect to
colorectal cancer incidence and progression.
A Survey on Low Power Design Approaches in Nanoscale Regime
Authors: Sharma Vijay Kumar
Published: June 2020

Background:

The increased demand for battery operated portable systems boost up the
field of low power VLSI design. Integrated circuits are enhancing the performance of the systems in
terms of lesser area requirement, higher functionality, and faster response at lower technology nodes.
The applied power supply and the threshold voltage of the individual device are scaled down at lower
technology node. Scaling of the threshold voltage of the devices raises the issue of leakage current.

Objective:

Leakage current should be made recessive with the continuous scaling of technology nodes.

Methods:

Various leakage current mitigation methods had been employed to reduce the leakage current
at different abstraction levels. This review paper demonstrates the survey of systematic arrangement
of device scaling, leakage power, its causes, and various methods to overcome the leakage current
at circuit level design.

Results:

3 input NAND (NAND3) gate is designed and simulated at 22 nm technology node on
HSPICE tool and analyzed for comparison of different leakage reduction techniques.

Conclusion:

INDEP approach is the most effective approach to reduce the leakage current and to improve
the reliability of the circuits followed by DTCMOS technique as compared to other available
techniques.
Intelligent Service and Metadata Management for Smart IoT Middleware
Authors: Park Jong-Hyun
Published: June 2020

Background:

In IoT (Internet of Things) environment, a number of sensors and networks
exist and they have various and heterogeneous characteristics. Applications, which provides a variety
of services based on the sensor networks, also have different service requirements. Therefore, a middleware
that is located between sensor networks and application systems is needed for integrating
two layers.

Objective:

This paper proposes a general-purpose middleware for providing intelligent services based
on heterogeneous sensors existing in the IoT environment.

Methods:

The proposed middleware acquires and manages sensing data in real-time. The middleware
stores and manages heterogeneous sensors, node, and network metadata. In addition, the middleware
infers the situation based on ontologies and rules and provides intelligent services.

Results:

The paper has proposed integrated metadata to describe heterogeneous sensor, node and
network information. The third is the intelligent service management system to provide sensor-based
intelligent service to users. The paper has proposed the SS ontology for describing sensors and services
and proposed a method for providing intelligent services using the SS ontology and rules. Of
course, the three systems operate independently, so they can be used selectively as needed. This paper
implemented a prototype system based on the proposed method.

Conclusion:

We expect that the proposed middleware can be used in various applications for sensorbased
intelligent service processing. In the future, we plan to expand the method to provide an intelligent
service by automatically gathering semantic data.
Evolution of Clinical Outcome During Adolescents’ Psychiatric Inpatient Care: A Prospective Multiple Informant Study
Authors: Cairó Marta Ruiz , Urben Sébastien , Terren Morgane , De Rocquigny Hélène , Courossé Swen , Bisio Cecilia , Caspani Vivien , Legoux Céline , Petraglia Géraldine , Guignet Boris , Plessen Kerstin Jessica , Holzer Laurent
Published: June 2020

Background:

Examining the effectiveness and adequacy of adolescents’ psychiatric
inpatient treatment through multiple perspectives is crucial to provide the best care.

Objectives:

The aims of the current study were to examine the consistencies and discrepancies
between patients and clinicians and to understand how each group considered
the timing of improvement of symptoms and psychosocial difficulties of adolescents
during a psychiatric inpatient stay.

Methods:

The Health of the Nation Outcome Scales for Children and Adolescents
(HoNOSCA, assessing symptoms and psychosocial difficulties) was rated on a weekly
basis by patients and clinicians during a psychiatric inpatient stay. Data were collected
from 297 patients, 58.2% females.

Results:

Both clinicians and patients reported a significant decrease of the HoNOSCA
scores from admission to discharge, revealing that inpatient treatment is perceived as
helping the adolescents to alleviate their symptoms and psychosocial difficulties. However,
the item-by-item analyses indicated that patients and clinicians reported difficulties
in different symptoms and psychosocial domains. Moreover, the week-by-week
analyses revealed discrepancies in the perception of the time-course of clinical outcome-
changes between clinicians and patients, as well as between males and females,
and between voluntarily and involuntarily admitted patients.

Conclusions:

By integrating perspectives of patients and clinicians and their respective
timelines, as well as by taking into account the mode of admission and the patient’s
gender, this study provides a deeper understanding of the evolution of clinical outcome
during adolescents’ hospitalizations, which allows to adapt their treatment and therewith,
to help patients more efficiently.
Critical Insight into the Attributes of Emerging Novel Coronavirus (COVID-19) in India and Across the World
Authors: Doshi Gaurav M. , Ved Hemen S. , Thakkar Ami P.
Published: June 2020

The World Health Organization (WHO) has recently announced the spread of novel coronavirus
(nCoV) globally and has declared it a pandemic. The probable source of transmission of the
virus, which is from animal to human and human to human contact, has been established. As
per the statistics reported by the WHO on 11th April 2020, data has shown that more than sixteen lakh
confirmed cases have been identified globally. The reported cases related to nCoV in India have
been rising substantially. The review article discusses the characteristics of nCoV in detail
with the probability of potentially effective old drugs that may inhibit the virus. The research
may further emphasize and draw the attention of the world towards the development of an effective
vaccine as well as alternative therapies. Moreover, the article will help to bridge the
gap between the new researchers since it’s the current thrust area of research.
COVID-19: An Opinion of Prevention and Dietary Based Management Hypothesis
Authors: Youssef Ashraf Talaat
Published: June 2020

Mentions the pandemic as starting in China, with a subsequent worldwide spread. The viral
infection can seriously affect multiple organs, mainly lungs, kidneys, heart, liver, and brain, and may
lead to respiratory, renal, cardiac, or hepatic failure. Vascular thrombosis of unexplained mechanism
may lead to widespread blood clots in multiple organs and cytokine storms that are a result of overstimulation
of the immune system subsequent to lung damage, may lead to sudden decompensation due
to hypotension and cause more damage to liver, kidney, brain or lungs. Until now, no drug has proved to
be efficient in getting rid of the problem and controlling the pandemic mainly depends on preventive
measures. Many measures can be considered to prevent the worldwide spread of the viral transmission.
Polyunsaturated long chain fatty acids (PUFAs), medium chain saturated fatty acids (MCSFAs), and
their corresponding monoglycerides have high antiviral activities against the enveloped viruses, which
reached more than 10,000 -fold reduction in the viral titers in vitro and in vivo after testing for gastric
aspirate, and can contribute to the systemic immunity against the enveloped viruses.
Teasing people into health? Sami cartoons, Indigenous humour, and provocative therapy
Authors: Egerer Juliane
Published: June 2020

Maren Uthaug's razor-sharp and self-deprecating cartoons reflect Sami people in a seemingly offensive way, addressing sensitive Indigenous issues such as cultural disorientation, racism, suicide, and addiction in an outspoken way. However, it was Sami people – Uthaug's relatives – who asked for and successfully published these cartoons. Why do Sami people request cartoons like these? Outlining some relevant aspects of highly divergent Western Comics Studies, the analysis and interpretation of selected cartoons is an opportunity to compare Uthaug's provocative strategies to the functions of humour in First Nations literature. Accordingly, the paper focuses on Indigenous humour as a means of emotional and social healing in the processes of decolonization and reconciliation and, additionally, adopts Frank Farrelly's concept of provocative therapy which is defined as a way of teasing people into health. Relying on Native American Terry Tafoya's (Taos Pueblo) description of Farrelly as a kind of medicine man, the paper asks whether also Uthaug acts as a cartoon-drawing Chiffoneti, a blend of priest, healer, and trickster regarding Indigenous and non-Indigenous readers.
Исследование влияния ионной проводимости на коэффициент оптического поглощения кристаллов трибората лития при воздействии высокоинтенсивного непрерывного лазерного излучения
Authors: Грищенко И.В. , Стирманов Ю.С. , Коняшкин А.В. , Рябушкин О.А.
Published: June 2020

We have introduced the results of investigation of influence of ionic conductivity of lithium triborate crystal (LBO) on the optical absorption and the heat transfer coefficients in incident of high-intensity laser radiation at wavelength 1070 nm.
Using Twitter to Surveil the Opioid Epidemic in North Carolina: An Exploratory Study (Preprint)
Authors: Anwar Mohd , Khoury Dalia , Aldridge Arnie P , Parker Stephanie J , Conway Kevin P
Published: June 2020

BACKGROUND

Over the last two decades, deaths associated with opioids have escalated in number and geographic spread, impacting more and more individuals, families, and communities. Reflecting on the shifting nature of the opioid overdose crisis, Dasgupta, Beletsky, and Ciccarone offer a triphasic framework to explain that opioid overdose deaths (OODs) shifted from prescription opioids for pain (beginning in 2000), to heroin (2010 to 2015), and then to synthetic opioids (beginning in 2013). Given the rapidly shifting nature of OODs, timelier surveillance data are critical to inform strategies that combat the opioid crisis. Using easily accessible and near real-time social media data to improve public health surveillance efforts related to the opioid crisis is a promising area of research.

OBJECTIVE

This study explored the potential of using Twitter data to monitor the opioid epidemic. Specifically, this study investigated the extent to which the content of opioid-related tweets corresponds with the triphasic nature of the opioid crisis and correlates with OODs in North Carolina between 2009 and 2017.

METHODS

Opioid-related Twitter posts were obtained using Crimson Hexagon, and were classified as relating to prescription opioids, heroin, and synthetic opioids using natural language processing. This process resulted in a corpus of 100,777 posts consisting of tweets, retweets, mentions, and replies. Using a random sample of 10,000 posts from the corpus, we identified opioid-related terms by analyzing word frequency for each year. OODs were obtained from the Multiple Cause of Death database from the Centers for Disease Control and Prevention Wide-ranging Online Data for Epidemiologic Research (CDC WONDER). Least squares regression and Granger tests compared patterns of opioid-related posts with OODs.

RESULTS

The pattern of tweets related to prescription opioids, heroin, and synthetic opioids resembled the triphasic nature of OODs. For prescription opioids, tweet counts and OODs were statistically unrelated. Tweets mentioning heroin and synthetic opioids were significantly associated with heroin OODs and synthetic OODs in the same year (P=.01 and P<.001, respectively), as well as in the following year (P=.03 and P=.01, respectively). Moreover, heroin tweets in a given year predicted heroin deaths better than lagged heroin OODs alone (P=.03).

CONCLUSIONS

Findings support using Twitter data as a timely indicator of opioid overdose mortality, especially for heroin.
COVID-19 Outbreak and Suicides in Nepal: Urgency of Immediate Action (Preprint)
Authors: Acharya Shiva Raj , Moon Deog Hwan , Shin Yong Chul
Published: June 2020

UNSTRUCTURED

Amid the COVID-19 pandemic, most of the people in the world are experiencing mental health problems. Nationwide lockdown had the negative consequences in many aspects of health of an individual in the community especially in mental health. This paper focuses on the suicides during the COVID-19 outbreak in Nepal. Current situation of COVID-19 pandemic is that cases are increasing in the high rate towards low income developing countries. With 9026 cases & 23 deaths due to COVID-19 in Nepal, suicide cases have shockingly high during corona outbreak. 875 cases of suicide have been reported till May 2020 relatively and will be increase in this COVID-19 pandemic period if no any effective & immediate response from the government and respective authorities. Long-term nationwide lockdown, fear & anxiety, economic crisis, weak corona outbreak control measures considered to be the factor beside the suicide. Mental health awareness program and modification on the nationwide lockdown based on the situation in the respective province should be addressed in order to promote the mental health of the citizens. All the health authorities, government, professionals & media need to come together to tackle suicide upsurge and prevention with effective management.
Effects of Web-Based Group Mindfulness Training on Stress and Sleep Quality in Singapore During the COVID-19 Pandemic: Retrospective Equivalence Analysis (Preprint)
Authors: Lim Julian , Leow Zaven , Ong Jason , Pang Ly-Shan , Lim Eric
Published: June 2020

BACKGROUND

The COVID-19 pandemic has negatively impacted psychological health. Mindfulness training, which helps individuals attend to the present moment with a nonjudgmental attitude, improves sleep and reduces stress during regular times. Mindfulness training may also be relevant to the mitigation of harmful health consequences during acute crises. However, certain restrictions may necessitate the web-based delivery of mindfulness training (ie, rather than in-person group training settings).

OBJECTIVE

The objective of our study was to examine the effects of mindfulness interventions during the COVID-19 pandemic and to evaluate the effectiveness of web-based interventions.

METHODS

Data from an ongoing study were used for this retrospective equivalence analysis. Recruited participants were enrollees from mindfulness courses at a local charity organization that promoted mental wellness. This study had no exclusion criteria. We created three groups; two groups received their training during the COVID-19 pandemic (in-person training group: n=36; videoconferencing group: n=38), and a second control group included participants who were trained before the pandemic (n=86). Our primary outcomes were self-reported stress and sleep quality. Baseline levels and changes in these variables due to mindfulness training were compared among the groups via an analysis of covariance test and two one-tailed t tests.

RESULTS

Baseline perceived stress (P=.50) and sleep quality (P=.22) did not differ significantly among the three groups. Mindfulness training significantly reduced stress in all three groups (P<.001), and this effect was statistically significant when comparing videoconferencing to in-person training (P=.002). Sleep quality improved significantly in the prepandemic training group (P<.001). However, sleep quality did not improve in the groups that received training during the pandemic. Participants reported that they required shorter times to initiate sleep following prepandemic mindfulness training (P<.001), but this was not true for those who received training during the pandemic. Course attendance was high and equivalent across the videoconferencing and comparison groups (P=.02), and participants in the videoconferencing group engaged in marginally more daily practice than the in-person training group.

CONCLUSIONS

Web-based mindfulness training via videoconferencing may be a useful intervention for reducing stress during times when traditional, in-person training is not feasible. However, it may not be useful for improving sleep quality.
Kajian evaluasi budaya organisasi Perpustakaan Nasional Republik Indonesia
Authors: Salahudin Salahudin , Nurmandi Achmad , Santoso Joko , Kusumawardhani Budi , Rusdianto Rusdianto , Agusta Rendra , Loilatu Mohammad  Jafar
Published: June 2020

Introduction. This study aims to determine the organizational culture in the National Library of Indonesia (NLI) based on several  aspects including clan (human resource management), adhocracy (innovation organization), market (adaptation and strategic organization), and hierarchy (coordination and organizational structure).

Research Methods. This study used a quantitative approach of Competing Values ​​Framework (CVF) developed by Cameron & Quinn (2011) to obtain data scores and the average of each aspect of organizational culture.

Data Analysis. Organizational Culture Assessment Instrument (OCAI) is an organizational culture assessment instrument by using statements/questions relating to the six subsystems, namely organizational culture dominant characters, leadership, human resource management, internal solidarity, strategic management and organizational success criteria. The data was analysed by using SPSS with Pearson Correlation formula.

Results and Discussion. We found that organizational culture of the National Library is cultural  hierarchy.

Conclusion and Recommendations. Organization culture of the (NLI) shows the cultural hierarchy. The cultural hierarchy is maintained as part of the working principles of the organization.
Perbandingan Pergerakan Titik Pantau Deformasi Kepulauan Sangihe Menggunakan Metode Perhitungan Periodik dan Simultan Berdasarkan Data GNSS Tahun 2014, 2015, dan 2016
Authors: Fauzi Muhammad Arsyad , Heliani Leni Sophia
Published: June 2020

The study of deformation monitoring point movement of Sangihe Islands was conducted using the GNSS measurement methods. One of the factor that determines the accuracy of the deformation monitoring is the utilized data processing methods. Therefore, this research analyze the comparison of deformation monitoring point movement of Sangihe Islands using periodic and simultaneous GNSS data processing methods. This research used three observations epochs of GNSS, i.e. 2014, 2015 and 2016. The observational data were processed using GAMIT/GLOBK software that tied to ITRF 2014 to produce coordinates and their accuracy. Based on the coordinate data and its accuracy, the velocity of movements calculation and their accuracy was done using the periodic and simultaneous methods. Based on the periodic method, the velocity of the SGH1 point on the N component is -1,11 ± 2,72 mm/year, on the E component is 9,21 ± 4,17 mm/year, and on the U component is -15,02 ± 50,64 mm/year, while the velocity of the SGH3 point on the N component is -4,93 ± 1,56 mm/year, on the E component is 16,50 ± 2,47 mm/year, and on the U component is -6,69 ± 19,42 mm/year. Based on the simultaneous method, the velocity of the SGH1 point on the N component is -1,56 ± 1,25 mm/year, on the E component is 9,40 ± 1,55 mm/year, and on the U component is -11,54 ± 5,83 mm/year, while the velocity of the SGH3 point on the N component is -5,18 ± 0,88 mm/year, on the E component is 16,91 ± 1,10 mm/year, and on the U component is -2,84 ± 3,49 mm/year. This research proves the hypothesis that the simultaneous GNSS data calculation results in higher accuracy than the periodic method.
Evaluasi Alih Fungsi Lahan Pertanian Menjadi Lahan Industri di Kabupaten Kendal Tahun 2014 - 2018
Authors: Adiyaksa Fitrian , Djojomartono, Ph.D. Prijono Nugroho
Published: June 2020

Kendal Regency is an agrarian area with a percentage of agricultural land 54.57% of the total land area of 1,002.23 km2. With the government programs of construction of the Kendal Industrial Park (Kendal Industrial Park) which was built on an area of 2,700 hectares. Most of the land used for development of the Kendal Industrial Area is agricultural land. The purpose of this study was evaluated about the suitability of land use change from agricultural land into industrial land in Kendal Regency in period of 2014 to 2018 with the Kendal Regency Regional Spatial Plan in 2011 - 2031. The research method was quantitative. The method of data collection in this study was census about industry location permit and land use change permit in Kendal Regency from 2014 to.d. 2018. The data collection technique in this research was documents review about secondary data from related institutions. Data analysis techniques in this study were divided into spatial analysis and statistical analysis. The spatial analysis technique used Geographic Information System (GIS) concept, and used overlay method on digital maps. Statistical analysis used to produce information in tables and graphs. The results of this study indicate about the growth in period 2014 to 2018, the number of land use permits increase to 134 permits devide by 34 industry location permit with covering area about 732,792 m2 and 100 land use change permit with covering area equal 690,303 m2. In addition, about 91.18% of industrial location permits and 62% of land use change permits from agriculture into industries in accordance with the Kendal Regional Spatial Plan between 2011 to 2031.
La noción de “fenómeno” en la fenomenología de Jean-Luc Marion
Authors: Roggero Jorge Luis
Published: June 2020

Me propongo aclarar la noción de “fenómeno” de Jean-Luc Marion y su relación con la categoría de “fenómeno saturado”. Para ello discutiré las interpretaciones de algunos comentaristas que advierten tensiones entre la primera y la segunda tópica del fenómeno.
Profil Tingkat Penalaran Ilmiah Siswa Sekolah Menengah Atas Pada Materi Ekosistem
Authors: Aulia Handayani Gina , Windyariani Sistiana , Yanuar Pauzi Rizqi
Published: June 2020

Scientific Reasoning is the systematic and logical thinking skills for problem solving. The purpose of this preliminary study is to find out the scientific reasoning profile of students in grade XI of Sukabumi City Public High School on Ecosystem material which was conducted in February in the 3rd week in one of the Sukabumi City State High Schools. This research uses descriptive method, the approach used is quantitative approach. Samples were taken using a purposive sampling technique of 30 students. This research instrument was in the form of a scientific reasoning test developed by Lawson namely the LCTSR (Lawson Classroom Test of Scientific Reasoning) type. The questions used consist of 35 multiple choice questions with LCTSR type with 6 indicators of scientific reasoning namely proportional, probabilistic, correlational, identification and control of variables, volume conservation and hypothetic-deductive. Data analysis with scoring technique is done in pairs which gives a description of the pattern and level of students' scientific reasoning abilities. From the results of the study showed that the scientific reasoning profile of class XI State Senior High School students in Sukabumi City in 2019/2020 had the highest reasoning pattern in the transitional operational category of 76.7% and had a level of scientific reasoning in the less-than-average category. average percentage of 30.05%. But these results must still be improved again by using methods, models and learning approaches that are able to train students' scientific reasoning.
Russian Military Capability in a Ten-Year Perspective – 2019
Authors: Hakvåg Una
Published: June 2020

Abstract: Russian Military Capability in a Ten-Year Perspective – 2019Una Hakvåg (Norwegian Defence Research Establishment (FFI)) reviews Russian Military Capability in a Ten-Year Perspective – 2019, an analysis of Russia’s Armed Forces and their fighting power, edited by Fredrik Westerlund & Susanne Oxenstierna.
Postponing Births – Comparing Reasons Among Women in St Petersburg, Estonia and Finland
Authors: Regushevskaya Elena , Hemminki Elina , Klemetti Reija , Rotkirch Anna , Karro Helle , Haavio-Mannila Elina , Miettinen Anneli
Published: June 2020

We compared the reasons for postponing first birth in the three neighbouring areas of St Petersburg (Russia), Estonia and Finland. Data from three population-based surveys among women aged 18–44 years in St Petersburg (response rate 67%); Estonia (54%) and Finland (63%) in the early 2000s were used and analysed with logistic regressions. Childbearing intentions and reasons for postponing parenthood differed between both study areas and age groups. The proportion of women aged 35–44 still planning to have children was highest in Estonia. In the two post-Soviet areas, job insecurity increased postponement intentions among women aged 18–34 years. Enrolment in education was an important reason for postponement among women below 35 years in Estonia and aged 25–34 years in St Petersburg. In Finland, poor economic situation in the youngest age group and desire to advance a career among all women were important reasons to postpone birth. The importance of prolonged education and job insecurity for the timing of births in St Petersburg and Estonia suggests that governments should improve family policy measures to encourage childbearing among the young. In Finland policies to support the reconciliation of family and career and to increase permanent employment could promote parenthood among well-educated women.
Ageing and Economic Performance: Dilemmas and Dichotomies
Authors: Rauhut Daniel
Published: June 2020

The process of ageing is not a new phenomenon. What implications ageing will haveon economic performance are unclear both in terms of magnitude and direction.Notwithstanding this however much that passes for research into the effects ofdemographic change is often highly partial and generally short-sighted oftenculminating in alarmist conclusions and providing a clarion call for significantpolicy changes based, ultimately, on rather thin scientific justification.The aim of this paper is to discuss the methodological and theoretical dilemmasand dichotomies concerning the interrelationship between ageing and economicperformance. There is actually little evidence that demographic changes per se willcause changes in the economic performance. By considering demography as destinyor the determinant for economic development, an artificial dichotomy is created.Furthermore, the spatial aspects are in general left outside the analysis. Ageing anddepopulation are not national problems, but local and in some cases regional.
Reproductive Health Services in Russia and CEE - a Review on Providers and Provider-Patient-Relations Research in English 1990-2010,
Authors: Larivaara Meri
Published: June 2020

Reproductive health services within Russia and Central Eastern European (CEE) postsocialistcountries received particular attention both internationally and nationallyin the early 1990s. There was a shared concern about access to proper services in thefield of family planning and antenatal care and about the knowledge, attitudes, andpractices of medical professionals. Yet comprehensive reviews of research literature onthe topic are difficult to find in English. This review was written to construct a generalview of the situation in Russia and CEE countries for the purposes of a research projecton reproductive health services in St. Petersburg. The review consists of empiricalreports and systematic reviews published in English. It is structured in two parts:(1) providers knowledge, attitudes and practices regarding family planning and (2)patient involvement in clinical decision-making and provider-patient relationships inreproductive health services.
Trends in Childbearing, Marriage and Divorce in Sweden: An Update with Data up to 2012
Authors: Andersson Gunnar , Kolk Martin
Published: June 2020

We present an update of the main and parity-specific trends in vital family-demographic behavior in Sweden presented in Finnish Yearbook of Population Research 2011. Based on Swedish register data, previous time series of relative risks of childbearing, marriage, and divorce by calendar year are updated with another five years of observation. We demonstrate that more than a decade of increasing fertility levels turned into moderate fertility declines in 2011. This trend reversal pertains to all main birth orders. Marriage propensities continued to increase for mothers but stagnated for the childless. Since the turn of the century, trends in divorce risks seem to have leveled off, altogether reflecting a more prevalent role of marriage in recent Swedish family dynamics.
Potential Hydrological Restrictions on Water Use in the Basins of Rivers Flowing into Russian Arctic Seas
Authors: Magritsky Dmitriy V. , Frolova Natalia L. , Pakhomova Olga M.
Published: June 2020

Water consumption has been evaluated for the basins of the rivers flowing into the Arctic seas of the Russian Federation and, separately, for the Arctic zone of Russia (AZR). Long-term dynamics of the major characteristics of water consumption are given for the period from the 1980s to 2017 along with data on its structure. The possible effect of the total water withdrawal and consumptive water use on river water inflow into the Arctic seas has been evaluated for the 1980s (a period of maximal anthropogenic load), for 2006–2017 and up to 2030. The volumes of water consumption in limits of AZR are relatively low. Moreover, the water withdrawal has dropped considerably compared with the situation in the 1980s, in particular, by about 30% in the Pechora, Lena river basins, and from the rivers of Murmansk oblast, and by 50% in the Northern Dvina, Yenisei, and Kolyma river basins. It has increased in the Nenets and Yamalo-Nenets AO because of the intense development of the local oil-and-gas complex. Nowadays, according to the authors’ estimates, 21.28 km3/year is being withdrawn in the drainage basins of RF Arctic seas and 2.58 km3/year, within the AZR, or 28.8 and 3.5% of the total volume in Russia. The largest contribution to this value is due to the water-management complexes in the basins of the Ob (14.7 km3/year), Yenisei (2.77), Northern Dvina (0.64), and Murmansk oblast (1.72 km3/year). The volumes of water discharges back into water bodies at the drainage basins of Russian Arctic seas are comparable with the volumes of freshwater withdrawal -71% of water intake. Even lesser is the difference within AZR. The major water users are the industry (with a high proportion of mining plants), thermal power engineering, and municipal economy. But considerable and diverse hydrological restrictions exist at the municipal level and for some water users in AZR. These local hydrological restrictions have been formulated and analyzed in detail, for the first time. They form three large groups. Original maps are given to illustrate the specific features and regularities in the present-day distribution of water-management characteristics over AZR.
Hazardous Ice Phenomena In Rivers Of The Russian Arctic Zone Under Current Climate Conditions And The Safety Of Water Use
Authors: Agafonova Svetlana A. , Vasilenko Alexander N.
Published: June 2020

The ice regime of the Russian Arctic rivers and its hazardous manifestations under current climate conditions are characterized. The ice phenomena in rivers in the region determine the conditions of navigation, water supply, hydropower station (HPS) operation, and the construction of temporary ice bridges and roads. Data of more than 100 hydrological gages over period from 1936 to 2016 were used to compile various cartographic materials and to analyze the spatial variations of the dates of ice phenomena, the duration of ice-free and ice cover periods, and the maximal ice thickness. Special attention is paid to the characteristics of level regime in periods with ice phenomena. Data on the frequency of floodplain inundation during spring ice run, the hazard of ice jams, and the seasonal features of the passage of maximal annual water level are generalized.

The observed changes in ice regime characteristics and ice hazard are analyzed. The years of the start of statistically significant shift of the periods of ice phenomena, caused by both climate changes and anthropogenic impact, are identified. The increase in the duration of the ice-free period was found to be not greater than 3–4 days for East Siberian rivers, 5–6 days for the Middle and West Siberian rivers, and up to 10–12 days for the rivers in the European part. A decrease in the maximal ice thickness is most pronounced in the rivers of the Northern European Russia, where it is 10–15 cm. The frequency of floodplain inundation during spring ice run remains constant.
DAMPAK SENSE, FEEL, THINK, ACT, RELATE DAN BRAND IMAGE TERHADAP KEPUASAN PELANGGAN CAFE DI SURABAYA
Authors: Indrawati Lilik , Amalia Devi Dian
Published: June 2020

ABSTRACT

This research was conducted on 150 respondens, through a questionnaire. The analysis used in this study uses the validity test, reliability test, classic assumption test, multiple linear regression test,determinant coefficient, and test. The results of data processing SPSS 22.0, namely: Sense has no effect on customer satisfaction PaperCup Coffee Surabaya because the value of t count < t table (1.030<1.977), then H0 is accepted and H1 is rejected. This means that there is no significant influence between sense and customer satisfaction at PaperCup Coffee Surabaya. Feel does not affect customer satisfaction PaperCup Coffee Surabaya because the value of t arithmetic < t table (0.953< 1.977) then H0 is accepted and H1 is rejected. This means that is no significant influence between feel and customer satisfaction at PaperCup Coffee Surabaya. Think does not affect customer satisfaction PaperCup Coffee Surabaya because the value of t arithmetic <t table ( 1.158 <1.977), then H0 is accepted and H1 is rejected. This means that there is no significant influence between think and customer satisfaction at PaperCup Coffee Surabaya.

Act affects customer satisfaction of paperCup Coffee Surabaya because the t value < t table (3.244> 1.977) with a significant level 0f 0.001< 0.050, then H0is rejected and H1 is accepted. This means that there is a significant influence between act and customer satisfaction at PaperCup Coffee Surabaya.Relate to customer satisfaction PaperCup Coffee Surabaya because t count value< t table (2.530> 1.977) with a significant level of 0.012 < 0.050, then H0 is rejected and H1 is accepted.This means that there is a significant influence between relate and customer satisfaction at PaperCup Coffee Surabaya. Brand Image has no effect customer satisfaction PaperCup Coffee Surabaya because the value of t arithmetic <t table (1.942<1.977), then H0 is accepted and H1 is rejected.This means that there is no significant influence between brand image and customer satisfaction at PaperCup Coffee Surabaya.Regression test result of multiple linear effect of the 6 independent variables that have the greatest contribution is act variable (X4) that is 0.328 or 32.8%. The result of the determinant coefficient show and adjusted R square of 0.441 (44.1%, meaning that the independent variables are sense (X1), feel (X2), Think (X3), Act (X4), Relate (X5) and Brand Image (X6) contributes moderately to the dependent variable, Customer Satisfaction (Y). The result of multiple linear regression:

Y= 3.078+0.075X1+0.095X2+0.107X3+0.328X4+0.253X5+0.176X6.

Based on the results of the study it can be concluded that the results of the adjusted R square of 0.441 0r 44.1%,which mreans, the independent variables are sense (X1), feel (X2), Think (X3), Act (X4), Relate (X5) and Brand Image (X6)contributes moderately to the dependent variable, Customer Satisfaction (Y).