bluuebunny/crossref_metadata_2025 huggingface dataset:
In accordance with the laws of the genre: the peculiarities of using uppercase letters in Internet memes and postcards
Authors: Ding Qiang
Published: June 2021

Internet memes and postcards as the popular carriers of Internet communications, implement new, simplified in literary and aesthetic level forms of communication. The process of creating such genres entails departure from orthographic rules, among which is the use of uppercase letters. The subject of the research is the determination of peculiarities of practical use of uppercase letters in Internet memes and postcards. The goal is to follow the observance of orthographic rules in these genres regarding the use of uppercase letters, as well as to identify the stylistic peculiarities of these two genres and characteristic use of uppercase letters. The relevance and scientific novelty of this article consists in examination of content creation for Internet memes and postcards, rather than memes themselves. Extralinguistic roots of the problem of liberal use or inobservance of uppercase letters are detected on the linguistic basis. The research leans on the content from open sources. The conclusion is made that both linguistic genres represent the examples of mass communications addressed primarily to the users with lower aesthetic demand; different linguistic gradation lead to certain departure from orthographic rules in both genres; this may not be progressive from the perspective of language development, but rather be oriented towards primitivization of content.
Specificity of realization of linguoculturological peculiarities of the Chinese language in the Russian linguistic system (on the example of translation of Mo Yan's novel “Life and Death are Wearing Me Out”
Authors: Gao Xin
Published: June 2021

The relevance of this topic is substantiated by increasing cross-cultural, interlingual and interethnic ties between Russia and China, as well as the overall trend of modern Russian philology towards studying the aspects of implementation of certain linguoculturological peculiarities of the Chinese language in the Russian language system. The goal is to reveal the specificity of linguistic means used in conveying linguistic and cultural peculiarities in translation of texts into the Russian language. The article explores the specificity of linguistic means used in Chinese-Russian translation, as well as describes the methods of translating texts into the Russian language to convey linguoculturological peculiarities of the Chinese language. The scientific novelty consists in the fact that this article is first within the framework of linguoculturological approach to conduct comprehensive analysis of the specificity of using linguistic means in Chinese-Russian translation. As a result, it is proven that the proper understanding and perception of texts translated from the Chinese language into the Russian language is based on the accurate translation that ensures equivalence with the original text, conveyance of the semantic meanings and emotional connotations instilled by the author. It is worth noting that in translation into the Russian language, an important role is played by both linguistic and extralinguistic factors.
Effects of speaking style on the shape of fundamental frequency distributions
Authors: Arantes Pablo
Published: June 2021

The present study has two main goals. The first is to describe the effects of three speaking styles (spontaneous interview, sentence reading and word list reading) on statistical estimators of fundamental frequency (f0) variability (mean, standard deviation, skewness and kurtosis) in five female and five male speakers of Brazilian Portuguese (BP). Most f0 contours of word reading are bimodal. Analysis of their time-normalized contours suggests this is caused by the time-compressed realization of fast transitions from low to high or high to low tones aligned with stressed syllables. Considering only unimodal distributions, results show that there are no statistically significant effects in the male data for any of the four variability estimators. Effects show up in female data. Spontaneous style has statistically significant higher mean, SD and skewness than read speech. Findings in the previous literature indicate the reverse pattern, though, for languages other than BP. The second goal of the study is to characterize the statistical properties of f0 distributions beyond mean and SD. Results confirm previous observations that most f0 distributions have positive skewness, are left-tailed and have kurtosis values that deviate significantly from the normal because of large deviations from the central or modal value. A distribution fitting procedure tested six distributions. The asymmetric Burr type XII distribution emerges as the one that best fits the data in the corpus. Results show that two of the parameters that determine its shape correlate well with the empirical f0 distribution values of SD and skewness. Important effects of speaking style on f0 seen in female speakers can be reproduced by combinations of the Burr distributions’ parameters.
Assistência aos pacientes que desenvolveram miocardite pós-infecção do COVID-19
Authors: Guerra Maria Luíza Alves , Costa Camila Carvalho Rodrigues , Ferreira Daniela Ferrari Angelo , Bisi Davi Heringer Coelho , Rezende Elisa Almeida , Fagundes Ludmilla Isadora Mendes , Moreira Mariana Vanon , Ferreira Pauline Christina Campos Martins , Fernandes Tiago Picolo , Boy Humberto de Freitas
Published: June 2021

Objetivo: Investigar, interpretar e revisar os achados sobre o desenvolvimento do fenótipo de miocardite viral após infecção por SARS-CoV-2, bem como os mecanismos fisiopatológicos envolvidos, para que seja possível a formulação de estratégias terapêuticas para prevenir e atenuar a evolução do quadro clínico. Revisão bibliográfica: Observa-se que os pacientes com piores prognósticos são os idosos ou aqueles que apresentam hipertensão arterial sistêmica, diabetes mellitus, doença arterial coronariana e insuficiência cardíaca. Estudos mostram que cerca de 10% dos pacientes infectados por COVID-19 desenvolveram miocardite e que 59% dos doentes com acometimento cardiovascular evoluíram para óbito intra-hospitalar. Isso se deve porque a COVID-19 causa lesão miocárdica que se manifesta por elevação dos níveis de troponina relacionando-se com o aumento da mortalidade. Outros marcadores de inflamação podem ser encontrados, como DHL, dímero-D, IL-6 e ferritina. A interação entre SARS-CoV e os receptores ACE-2 pode colaborar com a inflamação aumentando o dano no miocárdio. Considerações finais: O manejo dos pacientes com miocardite, é realizado por meio da utilização de imunossupressor e antiviral a fim de suprimir as respostas inflamatórias e autoimunes.
Análise dos encaminhamentos de pacientes cardiopatas adultos segundo o protocolo do Ministério da Saúde
Authors: Cintra Bruno Lima , Costa Michela Macedo Lima , Leite Camila Vilasboas Oliveira Cardoso , Araújo João Victor Santana , Santos Enyo Arruda , Porto Andressa Lima , Matos Luísa Nery , Mota Luana Maria Liborio da , Corrêa Shesllen Mikaelly Cruz , Rezende Ricely Almeida
Published: June 2021

Objetivo: Analisar se há obediência aos critérios expostos no protocolo ao solicitar uma consulta com médico especialista em cardiologia. Métodos: Trata-se de uma análise documental, quantitativa e retrógrada das fichas de solicitação de encaminhamento e prontuários dos pacientes cardiopatas adultos que foram referenciados de uma Unidade de Saúde da Família (USF) para consulta com cardiologista no município de Vitória da Conquista – Bahia. Com base nos parâmetros do protocolo de encaminhamento em cardiologia (PEABEC) do Ministério da Saúde. Os dados colhidos foram digitalizados para planilha do software Microsoft Office Excel. O estudo foi aprovado por Comitê de Ética em Pesquisa.  Resultados: A média de tempo de espera na fila foi de 498,3 dias para obtenção de nova consulta com cardiologista. A USF avaliada recebe em média três vagas mensais para esta finalidade. Dezesseis pacientes foram selecionados para avaliação documental com média de idade de 60,56 anos de modo que 50% era do sexo feminino e 43,75% masculino. Conclusão: Evidenciou-se uma lacuna nos registros de informações nos documentos analisados e no impacto negativo direto na priorização do acesso e na formação de longas filas.
El obispo Diego Ramírez de Villaescusa y su relación con el arte flamenco
Authors: Sáez Olivares Alejandro
Published: June 2021

En el presente trabajo se analiza la figura del obispo Diego Ramírez de Villaescusa y su papel como consumidor y comitente de obras de arte flamencas. Estamos ante un personaje integrado en los círculos de poder políticos, cercano a las últimas tendencias humanísticas y culturales, cuya carrera profesional le permitió acercarse a los principales focos artísticos de su tiempo.Como capellán mayor de la capilla de Juana, tuvo la oportunidad de acompañarla en su periplo flamenco, accediendo así al lujo y sofisticación de la Corte de Felipe el Hermoso. Comprobaremos cómo, aprovechando los contactos que su posición le facilitaba, adquirió algunas piezas de gran calidad, como el libro de horas de Leonor de la Vega, el tapiz de la Crucifixión o tablas devocionales, utilizándolas como presentes para agasajar a distintas personalidades. No obstante, también adquiriría obras para sí mismo, ya fueran libros o tapices, demostrando interés por el arte que se practicaba en territorio brabanzón. Asimismo, analizaremos las obras artísticas documentadas y su relevancia para la comprensión de Villaescusa como patrono de las artes.
Los hermanos Estuardo y los Wautier. Retratos de una familia real en el exilio
Authors: Sanzsalazar Jahel
Published: June 2021

El presente artículo examina la relación de los hermanos pintores del siglo XVII, Michaelina (Mons, 1604–Bruselas, 1689) y Charles Wautier (Mons, 1609– Bruselas, 1703), con los tres hijos mayores de Carlos I de Inglaterra, en el contexto previo a la restauración de la soberanía de los Estuardo en Gran Bretaña, mientras estaban en Bruselas, en el exilio. Junto al ya conocido Retrato de James, duque de York (Londres, 1633–1701), por Charles Wautier, se somete a investigación un anónimo retrato de dama vestida de rojo que se identifica con Mary Stuart, Princesa Real de Inglaterra y Princesa de Orange (Londres, 1631–1660), quien habría posado para la hermana de Charles, Michaelina, a principios de 1660, cuando es posible localizarla en Bruselas, pocos meses antes de su temprana muerte. El significativo hallazgo refuerza la relación de los Wautier con los Estuardo y nos invita a considerar un retrato del hermano mayor y pronto rey, Carlos II (Londres, 1630–1685), realizado en las mismas circunstancias.
La elocuencia de la pintura. Las puertas del archivo de la Universidad de Salamanca
Authors: Lahoz Lucía
Published: June 2021

Las pinturas de Martín de Cervera en las puertas del archivo de la Universidad de Salamanca, ubicado en 1613 en la Casa del Bedel, conforman un rico mensaje intervisual, dispuesto en distintos registros modales: narrativo, emblemático, heráldico, alegórico y epigráfico. Testimonian audiencias y prácticas docentes en las cátedras de Leyes y Teología, normas y disputas universitarias, en una representación que modula el registro sigilar del Estudio del siglo XVI, reforzando su promoción monárquica. Traducido a modelo narrativo, este sello subraya el carácter secreto del archivo y advierte de la inviolabilidad de los documentos en el ceremonial aurático de apertura del mueble que, cuando se cierra, sella -real y metafóricamente- con esta impronta, el lugar donde se custodia la matriz. Un documento figurativo imprescindible en la construcción del relato institucional universitario.
ИССЛЕДОВАНИЕ СТРУКТУРЫ И СВОЙСТВ ВЫСОКОЭНТРОПИЙНОГО СПЛАВА AlCoCrFeNi ПОСЛЕ ЭЛЕКТРОННО-ПУЧКОВОЙ ОБРАБОТКИ
Authors: Иванов Ю.Ф. , Громов В.Е. , Коновалов С.В. , Рубанникова Ю.А. , Осинцев К.А. , Чень C.
Published: June 2021

С помощью технологии проволочно-дугового аддитивного производства (WAAM) изготовлены образцы высокоэнтропийного сплава (ВЭС) Al-Co-Cr-Fe-Ni. Размеры зерен сплава изменяются в пределах от 4 мкм до 15 мкм. Вдоль границ и в объеме зерен выявлены включения второй фазы. Приграничные объемы сплава (объемы, расположенные вдоль границ зерен) обогащены атомами хрома и железа, объем зерен обогащен атомами никеля и алюминия, кобальт распределен в сплаве квазиоднородно. Установлено, что включения протяженной формы обогащены атомами хрома, железа и кислорода и могут являться карбидами. Определены микротвердость, модуль упругости, трибологические свойства. Проанализированы кривые растяжения. Установлено, что облучение ВЭА импульсным электронным пучком сопровождается освобождением границ зерен от выделений второй фазы, что свидетельствует об гомогенизации материала. Показано, что высокоскоростная кристаллизация расплавленного поверхностного слоя образцов ВЭС сопровождается формированием столбчатой структуры, имеющей субмикро- нанокристаллическую структуру. Установлено, что электронно-пучковая обработка приводит к снижению микротвердости поверхностного слоя сплава толщиной до 90 мкм, что может быть обусловлено релаксацией внутренних полей напряжений, сформировавшихся в исходном материале при его изготовлении. Выявлено, что облучение высокоэнтропийного сплава интенсивным импульсным электронным пучком приводит к увеличению прочности и пластичности материала. Предел прочности на сжатие увеличился в (1,1-1,6) раз.
ЭФФЕКТ КИНЕТИЧЕСКОЙ ПЛАСТИЧНОСТИ И ЕГО ПРИМЕНЕНИЕ ПРИ ПЛАЗМЕННОЙ НАПЛАВКЕ ТЕПЛОСТОЙКИХ СПЛАВОВ С НИЗКОТЕМПЕРАТУРНЫМ ПОДОГРЕВОМ
Authors: Малушин Н.Н. , Громов В.Е. , Романов Д.А. , Бащенко Л.П. , Ковалев А.П.
Published: June 2021

Исследовано влияние эффекта кинетической пластичности на характер формирования временных и остаточных напряжений при охлаждении образцов из наплавленного металла типа сплава Р18Ю и стали 12X17 на установке тепловой микроскопии ИМАШ-20-75. Показано, что в наплавленном сплаве Р18Ю наблюдается эффект кинетической пластичности при мартенситном превращении. Установлено, что соответствующим легированием наплавленного металла Р18Ю кобальтом можно регулировать уровень остаточных напряжений и вероятность образования холодных трещин. Регулирование величины остаточных напряжений происходит путем смещения кривой формирования временных напряжений в область более низких температур. Временные напряжения, накопившиеся при охлаждении металла в аустенитной области, в основном релаксируются в интервале мартенситного превращения и не получают дальнейшего развития при охлаждении до комнатной температуры вследствие малой величины интервала Мкусл – Тк. Стойкость наплавленного металла против образования холодных трещин при этом повышается. Приведена характерная структура поверхности наплавленного сплава Р18Ю. Отсутствие дефектов наплавки (пор, трещин, шлаковых включений) благоприятно сказывается на стойкости наплавленных деталей. Твердость после наплавки порошковой проволокой ПП-Р18Ю составляет 52 – 57 HRC. Трех – четырехкратный высокотемпературный отпуск при температуре 560 – 580 оС увеличивает твердость до 62 – 64 HRC. Структура наплавки при этом близка по своему составу к структуре теплостойкой стали Р18Ю в закаленном состоянии. Эффект кинетической пластичности можно использовать для регулирования напряженного состояния и предотвращения образования холодных трещин в наплавленных теплостойкими сталями высокой твердости деталях горно-металлургического оборудования. Промышленные испытания в реальных заводских условиях показали, что изготовленные с применением плазменной наплавки активного слоя теплостойкими сталями высокой твердости с регулируемым термическим циклом наплавленные детали обладают повышенной (в 1,5 – 2,0 раза) стойкостью по сравнению со стойкостью серийных изделий.
МОРФОЛОГИЯ СЛОИСТЫХ МЕТАЛЛОКОМПОЗИТОВ, ПОЛУЧЕННЫХ РАЗЛИЧНЫМИ СПОСОБАМИ
Authors: Бердыченко А.А. , Гурьев А.М. , Иванов С.Г. , Гурьев М.А. , Ситников А.А.
Published: June 2021

В работе представлены результаты сравнительной металлографии металлических слоистых композиционных материалов, полученных различными способами: сваркой взрывом и путем механического легирования смеси соответствующих порошков в механоактиваторе. Анализ морфологических особенностей строения и микроструктуры слоистых металлокомпозитов, полученных механическим легированием и сваркой взрывом проведен для материалов в состоянии как «до», так и «после» термической обработки. Полноценного травления обоих составляющих металлокомпозитного пакета, получаемого путем сварки взрывом разнородных материалов как правило не удается – обычно травится более активный материал. В случае соединения «сталь AISI 306+титан ВТ-1,0» это титан, в случае соединения «алюминий АМг6+титан ВТ-1,0» более активно травится алюминий. Вторая составляющая соединения разнородных материалов как правило, остается нетравленой. Однако, зона соединения материалов во всех случаях травится достаточно контрастно, что позволяет с высокой детализацией рассмотреть морфологические особенности ее строения. Картины травления и морфология слоистых композиционных материалов, получаемых путем механического легирования, имеют более высокую контрастность. При последовательном травлении исходной смеси порошков титана и алюминия реактивом Кролла в течение 10 с, а затем – в реактиве Века в течение 30 с удается добиться практически полной травимости частиц как титана, так и алюминия. После обработки в механоактиваторе травимость частиц алюминия оказывается выше травимости частиц титана. Однако, дефекты частиц титана (трещины, границы частиц, скопления дислокаций и т.д.) травятся все еще достаточно контрастно.
Non-classical properties and generation schemes of superposition of multiple-photon-added two-mode squeezed vacuum state
Authors: Dat Tran Quang , Thang Truong Minh , Duc Truong Minh
Published: June 2021

In this paper, we study some non-classical properties and propose the generation schemes of the superposition of multiple-photon-added two-mode squeezed vacuum state (SMPA-TMSVS). Based on the   Wigner function, we clarify that this state is a non-Gaussian state, while the original two-mode squeezed vacuum state (TMSVS) is a Gaussian state. Besides, the SMPA-TMSVS is sum squeezing, as well as difference squeezing. In particular, the manifestation of the sum squeezing and the difference squeezing in the SMPA-TMSVS becomes more pronounced when increasing parameters r and e. In addition, by exploiting the schemes of photon-added superposition in the usual order, we give some schemes that the SMPA-TMSVS can be generated with the higher-order photon-added superposition by using some optical devices.
Magneto-optical absorption coefficients in monolayer MoSe2
Authors: Bich Tran N. , Phuc Huynh V. , Dinh Le
Published: June 2021

We study the linear, third-order nonlinear, and total absorption coefficients (OACs) caused by intra- and inter-band transitions in monolayer MoSe2 in the presence of a magnetic field by using the compact density matrix approach. The results show that the OACs display the blue-shift behaviour with an increase in the magnetic field. The Zeeman fields do not affect the peak positions but reduce peak intensities slightly. Besides, the strong spin-orbit coupling in monolayer MoSe2 causes the peaks to differ significantly due to spin-up and spin-down. The OACs due to intra-band transition display only one peak in the THz range, while the inter-band spectra show a series of peaks in the near-infrared optical range, making monolayer MoSe2 a promising candidate for novel optoelectronic applications.
Generation of plasmon-polaritons in epsilon-near-zero polaritonic metamaterial
Authors: Anh Nguyen Pham Quynh
Published: June 2021

In this paper, we study some non-classical properties and propose the generation schemes of the superposition of multiple-photon-added two-mode squeezed vacuum state (SMPA-TMSVS). Based on the   Wigner function, we clarify that this state is a non-Gaussian state, while the original two-mode squeezed vacuum state (TMSVS) is a Gaussian state. Besides, the SMPA-TMSVS is sum squeezing, as well as difference squeezing. In particular, the manifestation of the sum squeezing and the difference squeezing in the SMPA-TMSVS becomes more pronounced when increasing parameters r and e. In addition, by exploiting the schemes of photon-added superposition in the usual order, we give some schemes that the SMPA-TMSVS can be generated with the higher-order photon-added superposition by using some optical devices.
Implementation of Distance Learning and Assessment in Kindergarten in Emergency Circumtances
Authors: Purnamasari Nina , Heru Anggraeni , Herawati Fera
Published: June 2021

This study aims to get a clearer picture of distance learning (DL) in kindergarten and its assessment, to provide recommendations for policy options related to DL in kindergarten to optimizing students' development and abilities in the emergency. This study was randomly sampling subjects, which are principals, teachers, and parents who had kindergarten-age children. The data collection was through interviews, documentation, and questionnaires deployed by Google form. The results of this study showed that the best format of DL in kindergarten is blended. The assessment for this blended learning that can be done both by teacher and parents are by using communication forum and checklist sheets. Policy options for DL in kindergarten are the use of package modules/books, home visits, activity sheets, television and radio, and the coordination of the government at central and regional administration, and education stakeholders. These policy options become necessary because of the quality of DL based on the knowledge and skills of the teacher/parents that corresponds to the child's developmental stage. DL in kindergarten is the fulfillment of education rights to children in any circumstances. This effort optimizing the children's development of abilities and potential as expected
Negative correlation of single-cell PAX3:FOXO1 expression with tumorigenicity in rhabdomyosarcoma
Authors: Regina Carla , Hamed Ebrahem , Andrieux Geoffroy , Angenendt Sina , Schneider Michaela , Ku Manching , Follo Marie , Wachtel Marco , Ke Eugene , Kikuchi Ken , Henssen Anton G , Schäfer Beat W , Boerries Melanie , Wagers Amy J , Keller Charles , Hettmer Simone
Published: June 2021

Rhabdomyosarcomas (RMS) are phenotypically and functionally heterogeneous. Both primary human RMS cultures and low-passage Myf6Cre,Pax3:Foxo1,p53 mouse RMS cell lines, which express the fusion oncoprotein Pax3:Foxo1 and lack the tumor suppressor Tp53 (Myf6Cre,Pax3:Foxo1,p53), exhibit marked heterogeneity in PAX3:FOXO1 (P3F) expression at the single cell level. In mouse RMS cells, P3F expression is directed by the Pax3 promoter and coupled to eYFP. YFPlow/P3Flow mouse RMS cells included 87% G0/G1 cells and reorganized their actin cytoskeleton to produce a cellular phenotype characterized by more efficient adhesion and migration. This translated into higher tumor-propagating cell frequencies of YFPlow/P3Flow compared with YFPhigh/P3Fhigh cells. Both YFPlow/P3Flow and YFPhigh/P3Fhigh cells gave rise to mixed clones in vitro, consistent with fluctuations in P3F expression over time. Exposure to the anti-tropomyosin compound TR100 disrupted the cytoskeleton and reversed enhanced migration and adhesion of YFPlow/P3Flow RMS cells. Heterogeneous expression of PAX3:FOXO1 at the single cell level may provide a critical advantage during tumor progression.
CNKSR1 serves as a scaffold to activate an EGFR phosphatase via exclusive interaction with RhoB-GTP
Authors: Nishiyama Kanako , Maekawa Masashi , Nakagita Tomoya , Nakayama Jun , Kiyoi Takeshi , Chosei Mami , Murakami Akari , Kamei Yoshiaki , Takeda Hiroyuki , Takada Yasutsugu , Higashiyama Shigeki
Published: June 2021

Epidermal growth factor receptor (EGFR) and human EGFR 2 (HER2) phosphorylation drives HER2-positive breast cancer cell proliferation. Enforced activation of phosphatases for those receptors could be a therapeutic option for HER2-positive breast cancers. Here, we report that degradation of an endosomal small GTPase, RhoB, by the ubiquitin ligase complex cullin-3 (CUL3)/KCTD10 is essential for both EGFR and HER2 phosphorylation in HER2-positive breast cancer cells. Using human protein arrays produced in a wheat cell-free protein synthesis system, RhoB-GTP, and protein tyrosine phosphatase receptor type H (PTPRH) were identified as interacting proteins of connector enhancer of kinase suppressor of Ras1 (CNKSR1). Mechanistically, constitutive degradation of RhoB, which is mediated by the CUL3/KCTD10 E3 complex, enabled CNKSR1 to interact with PTPRH at the plasma membrane resulting in inactivation of EGFR phosphatase activity. Depletion of CUL3 or KCTD10 led to the accumulation of RhoB-GTP at the plasma membrane followed by its interaction with CNKSR1, which released activated PTPRH from CNKSR1. This study suggests a mechanism of PTPRH activation through the exclusive binding of RhoB-GTP to CNKSR1.
Analysis of Implementations Inclusive Education in Surabaya City
Authors: Sudarto Zaini , Sasongko Tri Budi
Published: June 2021

AbstrakImplementasi Pendidikan inklusif  di kota Surabaya telah di awali sejak tahun 2009 hingga saat ini tahun 2020, yaitu di 20 SD Kota Surabaya hingga sekarang berjumlah 50 SD Negeri dan 5 SD swasta, 20 SMP Negeri, 3 SMP Swasta, serta 2 SMA Negeri dan 2 SMK Negeri.  Pemkot Surabaya juga memberikan perhatian lebih untuk sekolah inklusi dan layanan khusus, dengan memberikan peralatan yang dibutuhkan, seperti guru pendamping, psikolog, fasilitas kursi roda, komputer braille, alat musik, dan lain sebagainya. Pelaksanaan Penelitian dalam Rangka analisis penyelenggaraan Pendidikan Inklusif di Sekolah SDN se Kota Surabaya sudah mencapai 75%, yaitu telah melaksanakan persiapan materi, persiapan instrumen, koordinasi dengan subyek penelitian yang telah ditentukan.Kata Kunci: Pendidikan, Inklusif, Surabaya AbstractThe implementation of inclusive education in the city of Surabaya has been initiated since 2009 until now in 2020, namely in 20 SD in the City of Surabaya until now there are 50 public SDs and 5 private SDs, 20 State SMPs, 3 Private SMPs, and 2 Public SMAs and 2 SMKs. Country. The Surabaya City Government also pays more attention to inclusive schools and special services, by providing the necessary equipment, such as accompanying teachers, psychologists, wheelchair facilities, braille computers, musical instruments, and so on. Research implementation in the framework of analyzing the implementation of Inclusive Education in SDN Schools throughout Surabaya has reached 75%, namely having carried out material preparation, instrument preparation, coordination with predetermined research subjects.Keyword: Education, Inclusive, Surabaya
Mentoring Children with Learning Difficulties in Inclusive Primary Schools
Authors: Nursaptini Nursaptini , Nzobonimpa Claver , Sobri Muhammad , Novitasari Setiani , Indraswati Dyah , Sutisna Deni
Published: June 2021

This study aims to determine the learning process for children learning difficulties in inclusive schools in elementary schools. This research is qualitative research with a case-study approach. The study was conducted at SDN 1 Sangkawana Batukliang District, Central Lombok Regency. Subjects in this study were the Principal, Low - grade teacher Data collection through non-participant observation, semi-structured interviews and documentation. Data analysis was performed using the Spiral Analysis model developed by Creswell. Research Findings that teacher competencies in the service of children with learning difficulties need to be possessed. The teacher is a determinant of the success of the learning process especially for children with learning difficulties who need more guidance in learning. In general, the learning process for children with learning difficulties in inclusive schools is the same as regular schools. The difference is in the provision of learning activities and services that are more remedial. This is done starting from the teacher doing adaptation in designing the Learning Implementation lesson plan by the circumstances of the students
The Rejuvenescimento da Mão com Hidroxiapatita de Cálcio Guiado por Ultrassom
Authors: Souza Hellen F. , C. Poggi Bárbara , C. Elias Mariana , Bravo Bruna S. F.
Published: June 2021

A volumização do dorso da mão é uma das regiões anatômicas mais frequentemente requisitadas durante a última década. A hidroxiapatita de cálcio é o material consagrado para esse procedimento desde o seu início, devido a seus diversos benefícios. Porém, apesar de consenso entre os médicos do preenchedor dérmico a ser aplicado, o mesmo não ocorre com a técnica a ser escolhida. Essa variação de métodos é devida à divergência entre os estudos anatômicos dessa região. Apresentamos dois casos tratados com hidroxiapatita de cálcio injetado pelo método ...... com controlo ultrassonográfico e, revisamos a literatura a fim de demonstrar o benefício do método de injeção confirmando o plano anatômico correto através de ultrassonografia.
Recalcitrant Palmoplantar Pustulosis: Have You Considered Allergic Contact Dermatitis?
Authors: Neves José , Brasileiro A. , Mendes-Bastos P.
Published: June 2021

Palmoplantar pustulosis (PPP) is a chronic and relapsing disease of the palms and soles, which tends to be difficult to treat. Classically it was described as a subtype of psoriasis. Nowadays it is regarded as a separate entity, although plaque-type psoriasis affects concomitantly many patients with PPP. A link between allergic contact dermatitis (ACD) and PPP has been described, and the former may encompass a potential to perpetuate the latter. Hereby we report two cases of difficult to treat plantar pustulosis. Underneath the dermatosis’s refractive nature was an allergic sensitization to potassium dichromate and cobalt chloride. Leather shoes and leather insoles were commonly worn, and both allergens are employed by the leather industry. Clinical remission was achieved in both cases with allergen eviction. Patch testing must be considered in cases of PPP without response to treatment. If relevant sensitization is found, allergen eviction measures are mandatory.
Perturbação Factícia Bolhosa Simulando Penfigoide Bolhoso: Relato de Caso e Revisão da Literatura
Authors: Ferraz Santino Mariana Franco , Conceição Fernandes Nurimar , Carvalho Quintella Danielle , Cuzzi Tullia
Published: June 2021

A perturbação factícia na dermatologia é uma dermatose que vem ocorrendo com maior frequência na população mundial. A prevalência em torno de 2% reportada nas clínicas dermatológicas é provavelmente é subdiagnosticada, já que o paciente não costuma estar ciente da sua natureza autoinfligida. Quando se manifesta por lesões bolhosas, pode ser confundida com doenças bolhosas autoimunes. Relata-se o caso de uma paciente de 59 anos acompanhada pela psiquiatria por depressão grave com sintomas psicóticos, amnésia dissociativa, síndrome de Munchausen e fibromialgia, que desenvolveu bolhas tensas no dorso do pé esquerdo. Os achados do primeiro exame histopatológico sugeriam penfigoide bolhoso, sendo realizado tratamento com prednisona. Devido à persistência e localização fixa das lesões, aos antecedentes psiquiátricos e à imunofluorescência direta negativa, novo exame histopatológico foi realizado e interpretado como um caso de perturbação factícia bolhosa.
Treatment of BRAF-Mutated Metastatic Melanoma: Immunotherapy or Target Therapy?
Authors: Rodrigues Ana Sofia , Brinca Ana
Published: June 2021

Metastatic melanoma has been associated with a poor prognosis, with overall survival rates at 5 years of 10%. Until 2011, the only treatments available for metastatic melanoma were chemotherapy and immunotherapy with interleukin-2. The more in-depth knowledge about the molecular biology of melanoma and the identification of BRAF mutations, which are the most frequently found, allowed us to find new therapeutic targets that came to modify the prognosis of these patients. Currently, the treatments available for metastatic melanoma with BRAF mutation are immunotherapy with immunological checkpoint inhibitors (anti-PD-1 to anti-CTLA-4) and targeted therapy with BRAF inhibitors and MEK inhibitors. However, the first-line therapy to be instituted in these patients remains unknown.
Confecção de Brincos de Borracha no Intraoperatório para Otimizar o Tratamento Cirúrgico de Quelóides no Lóbulo da Orelha: Série de Casos
Authors: Bacellar Nunes de Brito Juliana , Oliveira Silveira Samira , Oliveira das Neves Mota Alline , Silva Nascimento Mayara , Oliveira Carneiro Francisca Regina
Published: June 2021

Introdução: Quelóides são tumores benignos de pele causados por alterações no processo de cicatrização de feridas. As opções terapêuticas disponíveis são diversas e a associação entre as técnicas é comumente utilizada.

Métodos: Efetuámos a avaliação do tratamento combinado de ressecção cirúrgica de quelóide no lóbulo da orelha com posterior colocação de brinco de pressão utilizando êmbolos estéreis de seringas de 5 mL, que permaneceram no local durante 30 dias, combinado com injecção intralesional de corticoide aos 15 dias.

Resultados: Foram avaliados cinco pacientes (3M/2F) com média de 22 anos, com quelóides recidivantes dos lóbulos auriculares tratados no Hospital Jean Bitar, estado do Pará, no ano de 2019 a 2020. O procedimento decorreu sem incidentes e o resultado estético foi considerado muito bom, sem recidiva após 6 meses

Conclusão: Este procedimento cirúrgico combinado e a confecção do brinco foi considerada de baixo custo, fácil reprodutibilidade e com bom resultado estético final e boa tolerabilidade
Furuncular Myiasis of the Scalp, an Unexpected Diagnosis
Authors: Vale Gonçalo , Simões Mariana , Afonso Paula
Published: June 2021

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Biomarcadores na Urticária Crónica Espontânea
Authors: Pratas Nunes Inês , Gonçalo Margarida
Published: June 2021

Introdução: Atualmente, a compreensão sobre a etiopatogenia da urticária crónica espontânea é escassa. Devido à carência de dados sobre a sua etiologia, o tratamento disponível tem apenas como objetivo o controlo sintomático, com a maioria dos doentes a serem resistentes à primeira e segunda linha terapêutica (anti-H1 de segunda geração). Tendo em conta o seu impacto no doente e o difícil controlo sintomatológico, surgiu a necessidade de investigar marcadores de resposta ao tratamento da urticária crónica espontânea.
Métodos: Realizou-se uma revisão sobre biomarcadores que permitem guiar na prática clínica a escalada terapêutica destes doentes, permitindo um controlo mais eficaz e precoce da urticária.
Resultados: Na urticária crónica espontânea (UCE) têm sido investigados muitos biomarcadores, mas são ainda escassos e por vezes contraditórios os resultados sobre a sua capacidade de prever a resposta à terapêutica. A maioria dos estudos é concordante na menor reatividade aos anti-H1 perante níveis de PCR ou D-dímeros elevados e nas formas de UCE autoimunes. Neste último caso, se predominarem anticorpos IgG anti-FcεRI ou anti-IgE (autoimunidade tipo IIb), os doentes habitualmente têm o teste do soro autólogo e o teste de ativação dos basófilos positivos, basopenia, eosinopenia e IgE sérica total baixa ou muito baixa, e a resposta ao omalizumab costuma ser pobre e/ou lenta, mas tendencialmente favorável à ciclosporina. Se predominar a IgE anti-self (autoimundade tipo I ou autoalergia) a IgE sérica total é normal ou elevada, na ausência dos marcadores característicos da autoimunidade IIb, e a resposta à ciclosporina é pobre, mas bastante favorável e rápida ao omalizumb. A elevação dos D-dímeros prediz uma reposta desfavorável aos três fármacos.
Conclusão: Na UCE resistente aos anti-histamínicos de segunda geração, habitualmente com PCR e D-dímeros elevados, os doentes que respondem favoravelmente à ciclosporina e lentamente ao omalizumab têm normalmente uma autoimunidade tipo IIb subjacente e os doentes refratários à terapêutica com ciclosporina e que respondem rapidamente ao omalizumab têm subjacente uma autoimunidade tipo I ou autoalérgica. Estes subtipos podem ser indiretamente avaliados pelos níveis séricos de IgE total, pelos valores de basófilos e eosinófilos circulantes e pelos testes do soro autólogo e de ativação dos basófilos. Contudo, são ainda necessários mais estudos para estabelecer biomarcadores mais precisos que auxiliem na seleção da escalada terapêutica.
THE RELATIONSHIP BETWEEN THE PRICE OF PETROLEUM PRODUCTS AND THE COMPETITIVENESS OF TEXTILE ENTERPRISES IN RUSSIA
Authors:   Рeoples’ Friendship University of Russia (RUDN University), Glyuzitskiy K.К. , Korenevskaya A.V. ,   Рeoples’ Friendship University of Russia (RUDN University)
Published: June 2021

The article discusses trends in the textile industry, the pace and direction of use of synthetic fabric, key factors affecting the competitiveness of textile enterprises specializing in synthetic fibers. The necessary components are identified for the effective functioning and rapid entry into the world market of competitive enterprises in the textile industry of Russia. The paper addresses the problems of volatility of crude oil and the related instability in the price policy of synthetic fabric. The author concludes that it is necessary to actively stimulate and develop textile enterprises, considering the change in the oil market in 2020, as well as the current expansion of the use of synthetic fabrics.
DIRECTIONS FOR IMPROVING SOCIAL ACTIVITIES IN ORGANIZATION OF ENERGY HOLDING
Authors:   Financial University under the Government of the Russian Federation, Vasilieva T.B. , Sharkova A.V. ,   Financial University under the Government of the Russian Federation
Published: June 2021

The article discusses issues related to the efficiency of social activities of the organization of an energy holding. The social activity of the organization in relation to employees is assessed as one of the main components of the indicator of the effectiveness of the social activity of the organization and one of the priority areas of development.
MARKETING FACTORS THAT DETERMINE THE CONSUMER BEHAVIOR OF GENERATION Z
Authors:   State University of Management, Soldatova N.F , Kutnyuk I.V ,   Financial University under the Government of the Russian Federation
Published: June 2021

The concept of «Industry 4.0», which is actively developing in Russian companies, involves the end-to-end digitalization of assets and their integration into the digital ecosystem, developing the chain of creating the actual value of a product (service). As digital ecosystems develop, marketing, including strategic marketing, is also being modernized. SMM is being transformed from «page management in social networks» to one of the main marketing tools of our time. The choice of social platforms for the company’s presence is an important moment in the formation of the SMM-strategy. Companies implementing SMM should create optimal marketing content that will strengthen relationships with consumers and ensure not only long-term and favorable communications, but also create sustainable results in the activities of companies. Today, more than 25% of the working-age population of Russia is accounted for by generation Z, which has replaced millennials, which has its own characteristics and specifics of consumer behavior. For a deeper understanding of Generation Z consumers, the authors conducted a study of the factors that influence the model of consumer behavior in the B2C market.
METHODOLOGICAL APPROACHES TO ASSESSING THE STATE OF HUMAN CAPITAL IN THE REGIONS OF THE NORTH CAUCASUS FEDERAL DISTRICT
Authors:   Stavropol Institute of cooperation (branch) of ANO VO «Belgorod University of cooperation, economics and law», Berezhnoy V.I. , Berezhnaya E.V. ,   FGAOU VO «North Caucasus Federal University», Glaz V.N. ,   Stavropol Institute of Cooperation (branch) of ANO VO «Belgorod University of cooperation, economics and law», Taran I.L. ,   Pyatigorsk Institut (FILIAL) FGAOU VO «SeveroKavkazsky Federal University», Kutovoy S.I. ,   Pyatigorsk Institut (FILIAL) FGAOU VO «SeveroKavkazsky Federal University»
Published: June 2021

The article discusses the main existing methodological approaches to assessing the state of human capital in the regions, and provides a critical analysis by comparing the positive and negative sides. The article substantiates that in modern realities for the assessment of regional human capital should be used available indicators recorded by the Federal State Statistics Service of the Russian Federation in all regions, which will ensure the comparability of calculations between different subjects and give a certain universality to the methods of assessing the state of human capital in the region. Justifies the author’s position of assessing the state of human capital in the region based on the socalled representative approach of interregional comparison, the undoubted advantage of which is the comparability of the assessment indicators, which excludes the influence of the area and population of the region on the calculation of specific indicators. It is shown, in addition, that this approach is based on regional statistics available and universal for all regions. In the article, based on the methodology for assessing the human capital of the region justified by the authors, an assessment of the state of the human capital of the regions of the North Caucasus Federal District for 2019 is carried out, according to the results of which the corresponding conclusions are made, indicating a fairly strong differentiation of the regions of the North Caucasus Federal District by individual components of human capital. In this connection, it is proposed to consider the integral index of the human capital of the region in the context of the influence of indicators of the elements of regional human capital on it in order to obtain more weighty guidelines for the development strategies of regional human capital. The methodological approach proposed in the article and the results obtained can be useful for the regions of the North Caucasus Federal District to develop development strategies and adjust existing programs for the development of human capital.
Флористичні найменування в поетичній збірці Віктора Лазарука «Літораль»: функціонально-стилістичний аспект
Authors: Омельковець Руслана , Христіанінова Раїса
Published: June 2021

У статті наведено набір фітономенів у художньо-поетичному мовленні В. Лазарука на прикладі поезій збірки «Літораль», здійснено аналіз семантико-стилістичного потенціалу цих лексем, з’ясовано функціонально-стилістичні особливості флоронайменувань як одиниць поетичного мовлення. Фактичний матеріал засвідчує продуктивність використання флоролексем у ролі стилістем та ексресем широкого емоційно-оцінного плану. Образна природа флоролексем підпорядковується індивідуально-авторському осмисленню.
Номінація небезпечних метеорологічних явищ у діалектному мовленні (на матеріалі українських східностепових говірок)
Authors: Онищенко Юлія
Published: June 2021

У статті досліджено найменування метеорологічних явищ, небезпечних для людини, в українських східностепових говірках, зокрема проаналізовано назви тривалого дощу, зливи, завірюхи, снігопаду, сильного морозу, вітру, бурі, спеки та ін.  Спостережено широке використання сем, засвідчено особливості номінації деяких метеономенів у коментарях місцевих жителів. Зафіксовані назви найчастіше представлено однослівними, рідше – багатослівними словосполученнями. Здійснено аналіз частотності вживання досліджених маніфестантів. Переважна більшість із них – лексика народного вжитку, інші номени – варіанти, виявлені в говіркових континуумах.
Особливості репрезентації соціальної дійсності засобами фразеології в медійному дискурсі
Authors: Князь Тетяна
Published: June 2021

У статті проаналізовано особливості репрезентації соціальної дійсності засобами фразеології української мови в медійному дискурсі. Розглянуто види структурно-семантичних трансформацій фразеологізмів: контамінація, субституція, розширення компонентного складу. У медійному дискурсі узуальні й трансформовані фразеологізми влучно характеризують актуальні суспільно-політичні події сьогодення.  Прагматичний потенціал фразеологізмів як засіб мовленнєвого впливу на комуніканта, посилення емоційності мовлення реалізовано  індивідуально-авторськими трансформаціями.
Релігійна лексика у західноукраїнських ЗМІ в період Другої світової війни
Authors: Ковтун Альбіна
Published: June 2021

У статті з’ясовано специфіку функціонування релігійної лексики у ЗМІ українських націоналістів у період Другої світової війни на тлі її вихолощення в тогочасних радянських газетах. Автор дійшов висновку, що специфічною ознакою виходу релігійної лексики за межі традиційного у ЗМІ ОУН було формування з її участю іронійно-сатиричних перифразних одиниць, спрямованих проти сталінської політики. Друкований орган радянської влади відверто уникав релігійних тем, і лише 1945 року вийшла розлога замовна стаття «З хрестом чи з ножем?» В. Росовича (Я. Галана), у якій автор активно послуговувався біблійними алюзіями, дошкульними художніми засобами, фразеологізмами тощо із зарезервованими для релігійної сфери лексемами. Соціальне замовлення «словесного огиджування» образу А. Шептицького та всієї Української греко-католицької церкви працювало на «вивітрення» релігійної семантики.
Evaluation of the Addition Refractory Waste as Aggregates in Concrete for Impeller KR
Authors: Cavalcanti Leal Joao Filipe , Ferreiro Quevedo Nogueira Ricardo Emilio
Published: June 2021

Refractories, materials used in steel works, are directly or indirectly, associated with a very wide range of environmental problems. When discussing the influence of refractories on the environment, one should consider: aspects related to the global environment, local environment, work environment and the generation of waste. Refractory wastes are historically disposed of as waste in industrial landfills. However, some of the refractory materials used have the potential to be recycled, contributing to environmental and economic sustainability. The addition of recycled aggregates in refractory concrete used to molded Impeller KR was evaluated for the development of refractory recycling technology after use. In general, the results of the dynamic slag test and industrial test indicated the potential of the use of recycled aggregates slide gate.
Full-scale Models for the Study of Repair Techniques on Brick Masonry Surfaces
Authors: Binda Luigia , Baronio Giulia , Cantoni Francesco , Rocca Paolo
Published: June 2021

A systematic approach to the study of durability of wall surface treatments has been set up by the authors since some years. The study, previously based on accelerated aging tests and subsequent measurement of surface deterioration of treated and untreated specimens, has now been extended to full-scale facades. Three small constructions designed by the authors with modular facades made of sandstone and/or soft-mud facing bricks have been built in open field. A continuous content of water in the subsoil can be provided so that the capillary rise of water into the masonry is assured; soluble salts can also be provided from the soil. Some of the facades have been treated with protective materials, some others will be treated after deterioration. Besides collection of data concerning the environment and the moisture and salt movements in the walls, the deterioration of the external surfaces, the influence of mortar joints on moisture distribution and of the position and exposure of the material on the deterioration are being taken into account. Comparison between the in-situ and laboratory results are being carried out in order to adjust the aging tests to the natural environment.