bluuebunny/crossref_metadata_2025 huggingface dataset:
Effect of far-red light on the production and diversity of ginsenosides in leaves of Panax ginseng Meyer
Authors: Mohanan Padmanaban , Yang Tae-Jin , Song Young Hun
Published: February 2023

Ginsenosides are the most valuable and pharmacologically active triterpenoid saponins found in Panax ginseng. Although light quality affects ginsenoside content, little is known about the underlying genetic and regulatory mechanisms. Additionally, the correlation between the adaptability of ginseng to shade and ginsenoside biosynthesis remains poorly understood. In the present study, transcriptome analysis of ginseng seedlings using RNA sequencing revealed that the expression of ginsenoside biosynthesis genes, including PgHMGR, PgFPS, PgSS, and PgUGT, was enhanced in shade conditions but downregulated by red light, indicating that far-red light might play an essential role in ginsenoside production. Further, gene expression analysis in adventitious roots and 2-year-old plants using qRT-PCR showed that the light quality-mediated expression patterns of ginsenoside genes varied with tissue and age. However, unlike the transcriptome, there was no difference in the total ginsenoside content in seedlings among various light conditions. Nevertheless, the amount of major protopanaxadiol-type ginsenosides increased under shade and red light conditions. Unlike seedlings and adventitious roots, there was a decrease in the expression of PgHMGR, PgFPS, PgSS, and PgDDS in 2-year-old plants, along with an increase in the ginsenoside content, under far-red light. Taken together, our findings suggest that far-red light is an important environmental factor for ginsenoside biosynthesis and diversification and provide information that can improve the quality of ginseng produced for medicinal purposes.
Hydro-climatic consequences on zooplankton diversity and abundance in perennial Vavuniya reservoir and seasonal Thandikulam reservoir in Vavuniya, Sri Lanka
Authors: Kottage Chamali Dinuka , Patrick Anton Emmanuel Selvakumar
Published: February 2023

Background

Zooplankton exhibit strong responses for minute changes in their habitat. Therefore, this study intended to investigate the impacts of hydro-climatic factors and related water quality variables on zooplankton abundance and diversity in the perennial Vavuniya reservoir (VR) and seasonal Thandikulam reservoir (TR), Vavuniya, Sri Lanka.

Results

Zooplankton diversity and abundance showed some peculiarities between seasonal and perennial reservoirs under varying hydro-climatic factors and water quality parameters during wet and dry seasons (July 2018–February 2019). There were 14 Rotifera, 4 Cladocera and 5 Copepod species in VR, and in TR, 12 Rotifera, 2 Cladocera and 5 Copepod species were identified. Although these reservoirs are located at proximity (2.48 km), the responses via zooplankton community structure toward environmental factors have been shown uniqueness to some extent. Significant negative correlation was observed for increasing $${\text{NO}}_{{3}}^{ - }$$

NO

3

-

 (p = 0.044) and $${\text{PO}}_{{4}}^{{{3} - }}$$

PO

4

3
-

 (p = 0.010) concentrations with zooplankton diversity in perennial VR; however, only $${\text{PO}}_{{4}}^{{{3} - }}$$

PO

4

3
-

concentration showed a significantly (p = 0.042) negative correlation in seasonal TR. Interestingly, total zooplankton abundance showed significant negative correlations with $${\text{NO}}_{{3}}^{ - }$$

NO

3

-

(p = 0.013) and $${\text{PO}}_{{4}}^{3 - }$$

PO

4

3
-

(p = 0.038) in perennial VR; however, insignificant negative correlation was observed in seasonal TR. Copepods make up the majority of total zooplankton abundance in both reservoirs and were significantly affected by increased atmospheric temperature. Cladocera abundance in VR was highly sensitive (p = 0.032; r = − 0.856) to changes in water level. Increasing water level significantly favors the total zooplankton abundance in the seasonal reservoir but not in perennial.

Conclusions

Sensitivity of zooplankton community structure varies between seasonal and perennial reservoirs in different magnitudes. This is due to the increasing temperatures, increasing phosphate levels and decreasing water levels with the combination of other factors resulting in specific responses of zooplankton diversity and abundance. Therefore, it would not be surprised to use zooplankton community structure to sense the vibrant responses of different freshwater habitats.
Potential protective effects of red grape seed extract in a rat model of malathion-induced neurotoxicity
Authors: Saadh Mohamed Jamal
Published: February 2023

Background and Aim: Exposure to pesticide mixtures used in agricultural practice poses a grave risk to non-target animals. This study aimed to determine whether red grape seed extract (RGSE, which is 95% bioflavonoids and equal to 12,000 mg of fresh red grape seed, and 150 mg of vitamin C) alleviated the changes in brain-derived neurotrophic factor (BDNF) level, acetylcholinesterase activity, oxidative stress, and apoptosis induced by orally administered malathion in a rat model of malathion-induced neurotoxicity.

Materials and Methods: Thirty-two adult male Wistar albino rats were divided into four groups and exposed to malathion with or without 4 weeks of RGSE treatment, treated with RGSE alone, or left untreated as controls. The animals were euthanized 24 h after last treatment. Brain samples were collected to measure acetylcholinesterase, superoxide dismutase (SOD), and caspase 3 activity, total antioxidant capacity (TAC), and BDNF levels.

Results: Malathion significantly reduced acetylcholinesterase and SOD activity and TAC and significantly increased caspase 3 activity. In comparison, acetylcholinesterase and SOC activity, BDNF level, and TAC were improved and caspase 3 activity was decreased in the malathion-RGSE group, indicating that RGSE corrected the alterations detected in these biochemical parameters.

Conclusion: Oxidative stress and apoptosis in the brains of rats exposed to oral malathion were substantially controlled by RGSE treatment.
Utilização do GRACE no cálculo da recarga das águas subterrâneas no Sistema Aquífero Bauru na Bacia do Rio São Jerônimo - Triângulo Mineiro
Authors: Campos José Claudio Viegas , Gastmans Didier , Santarosa Lucas Vituri
Published: February 2023

A cidade de Gurinhatã, no Triângulo Mineiro, localizada na bacia do rio São Jerônimo, afluente do rio Paranaíba, tem no Sistema Aquífero Bauru (SAB) a única fonte de abastecimento de água para os mais de 5 mil habitantes da área urbana. Embora o SAB seja um importante aquífero do centro sul do Brasil, poucos estudos na sua porção mineira têm sido desenvolvidos para embasar seu uso racional. Nesse quesito, a avaliação da recarga das águas subterrâneas é fundamental para uma gestão eficaz dos recursos hídricos subterrâneos. O presente artigo teve por objetivo utilizar dados do sistema de satélites Gravity Recovery and Climate Experiment (GRACE), para determinar a recarga média anual do SAB na bacia do rio São Jerônimo. Concomitantemente, foram aplicados os métodos de Variação do Nível d’Água (VNA), em um piezômetro da CPRM, e o de decomposição de hidrograma com dados de uma estação fluviométrica. A recarga média anual para o período 2012 a 2018, obtida pelo método VNA, para uma porosidade eficaz (Sy) de 0,15, foi de 429 mm, para o da decomposição de hidrograma foi de 176 mm e para o de sensoriamento remoto foi de 408 mm. O método de recarga baseado em dados da variável GWS do GRACE se mostrou bastante eficaz, tendo uma boa correspondência com o método VNA, servindo como método alternativo ou complementar nos estudos de recarga de águas subterrâneas.
SELF Tool Platform in SaaS Model for Automation and Standardization of Solutions Generatione
Authors: Kraszewska Marta , Kraszewski Wojciech , Wojtas Jadwiga
Published: February 2023

In the article the functionalities and possibilities of using the SELF tool platform (Soneta Elevation LifeCycle Framework) are presented. The four defined layers of the platform are discussed, the process of implementing the solution and the integration of individual layers is presented. The market of ERP systems in Poland and alternative solutions available on the market are also discussed. The presented SELF platform, created in the SaaS (Software as a Service) model, is one of the key technological tools introduced in Soneta to implement an effective method of work organization within the firm and with its network of authorized partners.
Uniform Design of Heading and Track Controllers for Ship Autopilot
Authors: Stec Andrzej , Świder Zbigniew , Trybus Leszek
Published: February 2023

Uniform approach to selection of PID settings for heading and path tracking controllers that create a cascade control system for ship autopilot is presented. Uniformity of the design follows from observation that for each of the controllers the controlled plant looks like an integrator with time constant. In case of the heading controller, the plant is represented by the known Nomoto model. Due to elimination of the plant time constant by the controller, each of the closed loop systems becomes of 2nd order. One assumes that such system should have a double time constant, different in a prescribed ratio from time constant of the controlled plant. It is shown that the heading controller designed in this way suppresses disturbances better than the controller with standard settings.
Problems and Implementation of Liquid Flows in Automated Microdispensing Stations
Authors: Woźniak Klaudia , Olszewski Mariusz
Published: February 2023

The aim of the project described in the article was to develop assumptions for the automatic management of liquid microdosing processes with a volume of 0.5 μl in biomedical engineering. The structure of typical, catalog dispensers selected for testing, which does not guarantee the achievement of the volume of the mentioned portion of liquid, is presented. A set of the most important dependencies, phenomena and coefficients characterizing liquid microflows and their record, used in the calculator of the processor controller for the automated microdosing process, was given. The construction of a micro-dosing process measuring station, allowing for experimental verification of the quality of micro-dosing of liquids with the use of typical dispensers, developed dependencies and a processor controller of this process, was described by tested dispenser heads and the results of automated microportioning, meeting all the given assumptions of this process.
Modelling the Optimal Electricity Mix for Togo by 2050 Using OSeMOSYS
Authors: Tchandao Esso-Wazam Honoré , Salami Akim Adekunlé , Kodjo Koffi Mawugno , Nabiliou Amy , Ouedraogo Seydou
Published: February 2023

This work uses bottom-up modeling to explore the future evolution trajectories of the electricity mix in Togo by 2050. The objective is to investigate the evolution of the mix and the future investments needed to achieve the sustainable energy and climate change goals. Three scenarios were developed using OSeMOSYS. The reference scenario, named Business As Usual, closely reflects the evolution of the Togolese electricity sector under a business-as-usual assumption and planned capacity increases up to 2030. The second scenario, Net Zero by 2050, is based on the first scenario while ensuring that CO2 emissions cancel out in 2050 by following the Weibull law. The third scenario called Emission Penalty aims not only at the integration of renewable energies like the second one but also at the least cost electricity mix if emission penalties are applied. The results of the cost optimization indicate that photovoltaic and importation are the optimal choices ahead of gas and hydropower. The renewable energy aspect of the electricity mix is more highlighted in the last scenario. At the same time, the model shows that greater energy independence is achievable at the cost of a transitory increase in the cost of the electricity system. A tenfold investment effort is needed in 2030 to ensure either continuity of the status quo or a shift in strategy.
The Effect of Microencapsulated Starter Cultures on the Formation of Biologically Active Peptides in Finished Meat Products
Authors:   Gorbatov Federal Center for Food Systems RAS, Afanasev Dmitry A. , Chernukha Irina M. ,   Gorbatov Federal Center for Food Systems RAS, Ganina Vera I. ,   Razumovsky Moscow State University of Technology and Management, Mashentseva Natalya G. ,   Moscow State University of Food Production, Kovalev Leonid I. ,   Federal Research Center "Fundamentals of Biotechnology" of the Russian Academy of Sciences, Kovrizhnykh Anna V. ,   Moscow State University of Food Production, Ahangaran Mahboobeh ,   Moscow State University of Food Production, Gharaviri Mahmud ,   Moscow State University of Food Production
Published: February 2023

Of particular importance in the production of fermented meat products are starter cultures with a proteolytic system that promotes the proteolysis of the protein components of meat raw materials. Numerous compounds, which may have biological activity, were formed as a result of the proteolysis, for example, biologically active peptides or bacteriocins. Nevertheless, there are some technological difficulties in the use of bacteria that contribute to the formation of biologically active peptides in raw meat. The solution to this problem can be microencapsulation. In this study, industrially valuable strains of starter cultures were selected, and proteolytic activity genes were identified. Thus, the proteolytic genes of the PRTB10/PRTB20 and P15C/P06C families were found in the P. acidilactici 38 and P. pentosaceus 28 strains, while the genes of the Jp23/Jp25 and prti2/IP6Xba families were found in the L. acidophilus AT-45 strain. The prti2/IP6Xba genes were also found in the S. carnosus 111-2 strain. A technology is proposed for incorporating microorganisms into alginate capsules with an alginate gel concentration of 5%, which makes it possible to form strong capsules capable of maintaining the viability of starter cultures in the production of boiled sausage: when incubating heat-treated capsules to 72 °С on chalk agar, the survival rate of microorganisms from 30 to 90% was recorded. The protein profile of the samples of boiled sausages produced using microencapsulated starter cultures was studied. A significant interaction of some strains with proteins of the actomyosin complex was shown, and the enzymes of energy metabolism from muscle tissue were subjected to destructive changes - muscle creatine phosphate kinase, enolase, and adenylate kinase 1. The paper contains 4 Figures, 4 Tables, and 27 References. The Authors declare no conflict of interest.
Language representation of the literary subconcept “childhood” in Charles Dickens’s books
Authors:   Kuban State University, Katermina Veronika V. , Ivanova Yulia V. ,   Financial University under the Government of the Russian Federation
Published: February 2023

The article highlights the peculiarities of understanding the categories “literary concept” and “literary text” at the modern stage of language science development. The authors clarify the choice of the approach towards the analysis of literary concepts - from the perspective of cognitive linguistics, present a brief description of factors that influence the inner world of characters of Dickens’s books -the reflection of the social policy of England of that time. Employing a “semantico-cognitive” approach towards language analysis, the authors explain the main characteristics of the approach, define “cognitive interpretation” as a unique component of the “semantico-cognitive” method, which makes the analysis different from other approaches towards language study and gives an opportunity to achieve the most reliable results. The authors also describe peculiarities of implementing the “semantico-cognitive” approach, list additional methods used for working with the literary concept, mainly corpus linguistics methods: compiling of the corpus of texts, contextual analysis, compiling of concordance, qualitative analysis, descriptive method. The practical part begins with the description of results received via the semantic analysis of the subconcept “childhood”. During the analysis, a variety of semes has been identified; their hierarchy and percentage ratio are described. Further, the variety of semes is compressed into several cognitive characterisics by means of cognitive interpretation. The cognitive characteristics are the following: kindness, happiness, basis for life, blemish, unhappiness, game and study. The cognitive characteristics are organized in the form of fields of the subconcet “childhood”, where the most frequently verbalized, or pre-nuclear, one is “kindness”, and it is, presumably, the most important one for the author. All other characteristics are described in descending order, where “game and study” is the least frequently verbalized characteristic, it is of a backgound nature and is used for describing children’s routine. The graphic model describing the results of the research and its decoding are presented. The conceptual analysis is followed by examples from Charles Dickens’s books. The examples describe the cases of verbalization of different cognitive characteristics of the subconcept “childhood” that are parts of the context of the books Oliver Twist, Hard Times, A Christmas Carol, A Walk in a Workhouse. Contribution of the authors: the authors contributed equally to this article.
Book review: Tatsumi, Y. & Tsurumi, T. (eds) (2020) Publishing in Tsarist Russia: A history of print media from Enlightenment to Revolution. London: Bloomsbury Academic. 280 р.
Authors:   Institute of Scientific Information for Social Sciences of the Russian Academy of Sciences, Bogomolov Igor K.
Published: February 2023

The monograph is dedicated to the broad topic of the development of printing and publishing in Russia in the 18th - early 20th centuries. The study is not generalizing: this task is too complex and multifaceted. The authors touched upon different and at the same time interrelated subjects, some of which were practically not previously investigated. The reviewer notes that the project is based on Japanese historians and literary critics, which once again shows the productive work of Japanese historiography of late imperial Russia. Nine chapters of the monograph are divided into three parts according to the key periods: XVIII-XIX, XIX-XX centuries. and the eve of the 1917 Revolution. At the same time, thematic blocks are visible in each part. The first focuses on the Russian language and literature during the period of their transformation into a part of world culture. Y. Toriyama highlights the activities of the Society Striving for the Translation of Foreign Books created by Catherine II. A.I. Reitblat draws attention to the formation of the very concept of Russian classical literature. H. Kaizawa makes an attempt to rethink the “reactionary” 1880s, noting the importance of this period for the development of Russian literature, recognition of its importance and influence in Russia and around the world. The second part focuses on the development of the press of the peoples of the empire and the role of foreigners. The importance of the latter is noted by Y. Tatsumi, who speaks about several immigrants from Poland and Germany who managed to create large publishing firms in Russia in the second half of the 19th century. T. Inoue analyzes in detail the influence of the Russian press on the national identity and representation of the Kalmyks. D. Ross tells about the development of newspapers and magazines in the Tatar language, and A. Sakurama about the publishing activities of the baptized Tatars. Finally, the third part focuses on the impact of the 1905 Revolution and World War I on print and publishing. M. Stockdale examines in detail the period of 1914-1918, noting the importance of the press in the interest of Russian society in the events on the fronts of the war. T. Tsurumi briefly describes the situation and development of the Zionist press in Siberia and Chinese Harbin on the eve and during the Revolution and the Russian Civil War. On the whole, the monograph leaves the impression of a thorough work, in which important and interesting plots, though often poorly covered in historiography, are raised. Perhaps, there is a lack of a more detailed analysis of the development of the press during the revolutionary period, but this does not reduce the merits of the book, a rare example in modern historiography of late imperial Russia. The author declares no conflicts of interests.
Educational periodicals in the “court pedagogy” of Mikhail Muravyov and Vasily Zhukovsky. Article Three
Authors:   Novosibirsk State University, Dolgushin Dmitriy V.
Published: February 2023

The article analyzes Vasily Zhukovsky’s magazine Muraveynik (Anthill) and proves that it combines features of both an educational and a “circle” magazine. The starting point for Muraveynik was the educational context. But, unlike Sobiratel ’, Muraveynik had its educational nature smoothed and supplemented with “circle” features. The concept of the magazine implied cooperation between adult, eminent teachers of literature (Zhukovsky, who actually took over the duties of the editor-inchief of Muraveynik, and Pletnev, who became his assistant) and their very young students. The status of Muraveynik as a “circle” magazine was emphasized by its subtitle. Traditionally, researchers see this subtitle as a reference to the Arzamas circle. However, Muraveynik took the ideal of moral brotherhood from the Arzamas heritage, rather than game. In this sense, the conceptions of Muraveynik were closer to the “serious” circles originating in boarding schools, which also strongly influenced Zhukovsky: the Assembly of Noble Pupils of University Boarding School, the Friendly Literary Society. The Moscow Noble Boarding School strongly encouraged students’ literary creative works, their compositions and translations were constantly published in the school’s editions. In fact, when conceiving Muraveynik, Zhukovsky turned to this experience. He hoped to form around the magazine a friendly community uniting teachers and students in the field of literature. These hopes were not realized. Too young an age, a specific social affiliation and life priorities associated with it, and, finally, personal inclinations and abilities did not allow Zhukovsky’s students to respond to his life-building message. The students perceived Muraveynik more as part of the school routine than as an exciting intellectual adventure. Most of the “children’s” texts published in Muraveynik were not related to free creativity, but to the educational process and were often exercises performed as homework or class assignments. But in his own materials Zhukovsky actively tried to involve the “circle” context and even the life-building context. In this, he follows Mikhail Muravyov, who used the same strategy in Obitatel’ predmestiya (Suburban Dweller). As part of this “circle” strategy, Zhukovsky filled his texts in Muraveynik with motifs and allusions that build up two leading themes - idyllic and chivalrous. They were connected to each other in the life-building ideal of the chivalrous idyll. The author declares no conflicts of interests.
Non-standard graphic realizations in modern printed texts
Authors:   South Ural State University, Khakimova Elena M.
Published: February 2023

The article deals with violations of the callitypical norms regulating the use of fonts and compositional-spatial signs in a printed text. Norms and deviations of this type are represented in the modern orthology field, despite fundamental technical and technological changes in the media sphere. The theoretical foundations of the work trace their origin to papers on the functional and aesthetic aspect of printed graphics (E. Adamov, V. Toots, E.V. Oleshko, J. Tschichold, R. Bringhurst) and to orthological studies of callitypical norms (J. Vachek, A.A. Reformatsky, B.S. Schwarzkopf). The empirical basis was publications in Argumenty i Fakty and Cosmopolitan Russia for 2019. The author has revealed the following types of nonstandard callitypical realizations using the method of a systemic-functional analysis: total font accentuation (20 units); graphic overprotection (2 units); incorrect use of graphic markers in the main part of the texts (7 units); graphic polysemy and homonymy (72 units); graphic synonymy (51 units); non-normative compositional-spatial variants (5 units). All of them are associated with violations of semiotic symmetry between the signifier and the signified, which is characteristic of rigid systems, including printed language. These non-standard uses differ in terms of motivation, representing creative techniques (total font accentuation, graphic overprotection, ideographic synonymy) or callitypical mistakes (other non-standard variants). Units of the first type, when used appropriately, increase the expressiveness of printed tests; units of the second type complicate the solution of communicative tasks and reduce the level of the speech culture. The author pays attention to the criteria of callitypical normativity and shows that here, as in other orthological areas, the systems principle is in complicated interactions with traditional prescriptions. The study of graphic deviations proves that the callitypical norm creates clear architectonics and provides functional navigation. Therefore, it is advisable to comply with these requirements both in the press and in other types of printing product. The author declares no conflicts of interests.
Old Believer comics: To the history of the emergence of creolized texts in Siberia
Authors:   Tomsk State University, Esipova Valeriya A.
Published: February 2023

The article aims to consider the history of the appearance of the creolized text (CT) on Siberian materials of the late 19th century. A comic book is considered as a special case of such a text. Previously this kind of materials have not been used to study the history of CT. The article lists and briefly characterizes a number of works, mainly by domestic authors, on the problem of CT. It also indicates the presence of studies of certain types of CT, in particular - comics. The source of the study is a manuscript containing “Fasting Words” by Isaac the Syrian. The manuscript is stored in the Research Library of Tomsk State University (B-5548). It was written in 1894-1895 on the territory of Tomsk Province and belonged to one of the local Old Believers. The records on the manuscript - a scriber’s record of the work done and a record of the transfer of the manuscript as a schismatic one to Tomsk Theological Seminary - allow reconstructing its history. The illustrations of the manuscript were examined. Among them, those that can be called comics were identified: they include several plot-related parts and show the development of the story. Two illustrations were found that can be called comics: about silence and about nutrition. Each of the illustrations consists of three parts; to indicate the movement of time, the artist used a different position of the sun over the heads of the characters. Also three illustrations were found that can be called proto-comics. They do not have plot development, but they are a case of CT: there are images with captions that are closely related to the content of the main text. An important feature of the discovered illustrations is literalism in the transfer of the author’s text. A similar technique is used in modern advertising. There are other similar cases described by researchers. For instance, G.V. Markelov describes “frieze” miniatures in one of the manuscripts from the Northern Dvina. These are images glued together from several sheets of paper and containing several sequentially unfolding scenes from the text. The article concludes that the phenomenon of CT, including comics, which currently attracts a lot of attention from researchers, has a very long history, partly already covered in studies. CT can be observed in the Russian provinces at the end of the 19th century. It is characteristic that CT is seen primarily not in official publications, but in works related to reader reception - in handwritten books in particular. Thus, CT in the form of a comics book was known to the Siberian reader and was used to illustrate, in particular, patristic texts. The author declares no conflicts of interests.
mcSCRB-seq2 protocol v1
Authors: Esteban Wange Lucas
Published: February 2023

mcSCRB-seq2 is the improved version of our published protocol molecular crowding SCRB-seq (mcSCRB-seq) (https://www.nature.com/articles/s41467-018-05347-6/). Following changes were introduced: re-evaluted the Lysis Buffer formulation, making it more robust against RNAses added additional dCTP in the Reverse Transcription leading to higher yield by enhanced Template switching updated the oligo dT primers to be compatible with 10x's three prime gene expression layout (see prime-seq for more information) changed to KapaHifi for PreAmplification as it produces less chimeric rerads compared to Tera Polymerase increased Primer concentration in PreAmp (SingV6) included an option for cheaper library prep with NEBNext
G-7 ÜLKELERİNDE İŞSİZLİK HİSTERİSİ İÇİN BİR ANALİZ
Authors: KESİCİ Hülya ÇALIŞKAN
Published: February 2023

Bu çalışmanın temel amacı, G7 ülkeleri için 1984-2019 dönemi için zaman serisi ekonometrisi teknikleri kullanılarak, G7 ülkelerinde toplam işsizlik oranı değişkeninde Histeri etkisinin olup olmadığı test etmektir. İşsizlik oranında histeri etkisinin olup olmadığı, işsizlik oranı değişkenin durağanlığı test edilerek ortaya konulmuştur. Birim kök test sonuçlarına göre G7 ülkelerinde işsizlikte histeri etkisinin var olduğu sonucuna ulaşılmıştır. Bu bağlamda, işsizlik oranı değişkeni için karşılaşılan şokların doğal işsizlik oranında kalıcı etkilere yol açtığı, işsizlik oranı değişkenin zamana göre değişen bir ortalama etrafında durağan olmayan bir seyir izlediği sonucuna ulaşılmaktadır.
ÇAĞRI MERKEZİ SEKTÖRÜNDE MOTİVASYON VE ÇALIŞANI MOTİVE EDEN FAKTÖRLER: BİR ALAN ARAŞTIRMASI
Authors: ÇAKMAK Faruk
Published: February 2023

Bu çalışmanın amacı, çağrı merkezi sektöründe çalışanların motivasyonları üzerinde etkili olan faktörleri belirleyip ana motivatörlerini tespit etmektir. Bu amaçla, Türkiye’de faaliyet gösteren bir çağrı merkezi işletmesinde görev yapan 721 çalışana anket uygulanmıştır. Anket sonucu elde edilen veriler SPSS programı kullanılarak analiz edilmiştir. Verilerin analiz aşamasında ana başlıklarda; tanımsal istatistik yöntemlerİ, korelasyon ve güvenilirlik analizleri, açımlayıcı faktör analizi ve parametrik analiz testlerinden yararlanılmıştır. Araştırmada elde edilen sonuçlara göre, çağrı merkezi sektöründe çalışanların motivasyonunu yüksek düzeyde etkileyen ana faktörler arasında; yeni ve zor görevlerde sorumluluk alma ve yeni şeyler öğrenebilecek fırsatlar yakalama konuları içsel motivasyon bağlamında, izin kullanılması gerektiğinde izin alınabilmesi ve çalışma arkadaşları ve yöneticileri tarafından gerekli desteğin alınması konuları ise; dışsal motivasyon kapsamında öne çıkmaktadır. Çalışmada ayrıca motivasyonun demografik özelliklere göre (cinsiyet, medeni durum, yaş, eğitim düzeyi, kıdem, pozisyon, çalışılan proje ve lokasyon) değişiklik gösterip göstermediği incelenerek, ortaya çıkan sonuçlar üzerinden karar vericilere ve gelecekteki çalışmalara önerilerde bulunulmuştur.
COVİD-19 DÖNEMİNDE TURİZM İLE İLGİLİ TWİTLERİN MAKİNE ÖĞRENMESİ YÖNTEMLERİYLE DUYGU ANALİZİ
Authors: KARAMAN Engin , ÇİLAN Çiğdem ARICIGİL
Published: February 2023

Tüm dünyada etkili olan ve küresel bir pandemi özelliği taşıyan COVİD-19 virüsü, Türkiye’de ki turizm tercihleri üzerinde de etkisini göstermiştir. Bu çalışmada, Nisan- Ağustos 2020 tarihleri arasında atılan turizm hahstagli (#turizm) Türkçe twitler üzerinden duygu analizi çalışması yapılmıştır. Veriler Twitter API uygulamasından elde edilmiştir. Bu süreçte toplanan 9678 adet ileti gerekli ön işleme ve dönüştürme süreçleri üzerinden yapılandırılarak 4202 adet olarak analize hazır hale getirilmiş ve iletiler anlamsal açıdan içerdikleri duygu ifadesine göre üç kategoride etiketlenmiştir. Duygu analizi çalışmalarında Makine Öğrenmesi’nin en çok kullanılan yöntemlerinden (algoritmalarından); Lojistik Regresyon Analizi, Karar Ağacı, Multinominal Naive Bayes Analizi, Kümeleme Analizi(k-En Yakın Komşu), Destek Vektör Makineleri ve Rassal Ormanlar kullanılarak sınıflandırma performansları karşılaştırılmış ve en başarılı model olarak 0.66 doğruluk skoruyla Lojistik Regresyon modeli olmuştur. Oluşturulan model geliştirilmeye açık olmakla birlikte tahminlime çalışmalarında kullanıma uygundur.
AN APPLICATION OF DATA ENVELOPMENT ANALYSIS TO DIGITAL MARKETING SECTOR
Authors: BAL Zeynep , DENİZ Eylem
Published: February 2023

Data Envelopment Analysis (DEA) is a special application of linear programming. It allows measuring the relative efficiency of companies through the outputs produced using many inputs. Efficiency analysis of decision-making units by evaluating many inputs and outputs can be done with this analysis. In recent years, DEA has been used in the evaluation of decision-making units in many areas.Within the scope of the study, advertising publications of a company that sells products of various brands were used and the maximization of the company's revenue was aimed in line with the decision-making units. For this purpose, Banker, Charnes and Cooper (BCC) output-oriented model was preferred. In this study on digital marketing, only the analysis results were included according to the confidentiality agreement.
İSTANBUL İLİNDE KIRMIZI ET VE ET ÜRÜNLERİ TÜKETİMİNİN MİKROBİYOLOJİK KİRLİLİĞE ETKİSİ
Authors: TARAKÇI Nadide Gizem , SEZGİN Funda H. , DÜMEN Emek , İSSA Ghassan
Published: February 2023

Et, insanlığın başlangıcından günümüze kadar temel bir besin maddesi olarak ilk sıralarda yer almıştır. Ülkemizde et talebini ve tüketimini etkileyen faktörler bulunmaktadır. Bunlardan bazıları tüketicinin gelir seviyesinin durumu, etin fiyatı ve tüketici tercihleri olarak sıralanabilir. Buna ek olarak tüketici alışkanlıklarında, bölgenin sosyal ve ekonomik yapısının da etkili olduğu söylenebilir. Et üretimini artırmaya yönelik çabaların yanında, tüketicilerin et tüketim alışkanlıklarının da belirlenmesi bü yük bir öneme sahiptir. Ülkemiz nüfusu hızlı bir şekilde artarken, beslenme için kullanılan kaynakların da aynı şekilde artırılması, verimli bir düzeye getirilmesi ve değerlendirilmesi zorunludur. Bu çalışmada, İstanbul ilinde 100 adet hanede et ve ürünler inin tüketim profillerinin belirlenmesi, tüketim alışkanlıklarının ve tercihlerinin et ve ürünlerinin mikrobiolojik kalitesini nasıl etkilediğinin ortaya konulması ve tüketici sağlığı açısından olası risk faktörlerinin araştırılmıştır. Çalışmamızdan elde e dilen sonuçlar eşliğinde tartışılan veriler, et ve ürünlerinin mikrobiyolojik kirlilik derecelerinin ve içerebileceği potansiyel risk faktörlerinin birincil derecede tüketicilerin tüketim profilleri, sosyo ekonomik durumları, tüketim ve satın alma alışkanl ıkları ile ilişkili olduğunu göstermiştir.
Análise etnobotânica de plantas tóxicas utilizadas na ornamentação urbana
Authors: F. A. Pimenta Aniele , A. Baldo Mateus
Published: February 2023

Introdução: As plantas são muito utilizadas em ornamentações devido à sua beleza característica, no entanto, existe uma diversidade muito grande de espécies na flora brasileira que produzem diversos metabólitos com potencial tóxico. Os vegetais são utilizados meramente por sua aparência física, sem que haja qualquer tipo de preocupação com a sua fisiologia, bioquímica, farmacologia e toxicologia. Um ponto muito comum nas cidades é a utilização de plantas que produzem metabólitos que causam problemas à saúde e podem levar até a morte de pessoas e animais. Elas são plantadas na frente das casas, jardins, praças, alpendres ou terraços, entre outros locais públicos de fácil acesso. Denominadas plantas tóxicas, esses vegetais podem até mesmo se tornar um problema de saúde pública devido ao mau uso e ao desconhecimento por parte da população. Objetivo: Esse trabalho teve como objetivo alertar sobre o perigo do uso de plantas tóxicas usadas para ornamentação, plantadas em locais públicos de fácil acesso e até mesmo dentro de residências. Métodos: Foi realizada uma pesquisa de campo na área central do município de Casa Branca – SP (latitude 21º46'26" sul e a uma longitude 47º05'11" oeste - altitude de 684 metros), na qual as plantas tóxicas foram fotografadas e posteriormente foi feita a identificação botânica baseada em análises de herbários virtuais. Resultados: Este trabalho apresentou diversas plantas tóxicas encontradas no centro da cidade de Casa Branca, cidade do interior do estado de São Paulo, descrevendo os metabólitos tóxicos, sintomas e características das espécies na tentativa de informar o público em geral do perigo dessas plantas. Conclusão: Conclui-se que é de extrema importância o conhecimento das plantas ornamentais tóxicas, pois somente com o alerta sobre a população as intoxicações poderão ser evitadas.
Síndrome da sela parcialmente vazia associada a deficiência do eixo gonadotrófico: relato de caso
Authors: Saade Tales C. H. , Silva Letícia L.G. Da , Sousa Raimundo C. De
Published: February 2023

A sela túrcica vazia é um diagnóstico realizado através do exame de Ressonância Magnética que a define como parcial quando menos de 50% da sela é preenchida com líquido cefalorraquidiano (LCR) e a glândula pituitária tem espessura ≥ 3 mm ou total quando mais do que 50% da sela é preenchida com LCR e a espessura da glândula tem ≤ 2 mm de diâmetro. Associada a essa condição, com prevalência de 8 a 35% na população geral, uma alta incidência de disfunção pituitária foi documentada. O presente trabalho tem como objetivo relatar o caso de um paciente masculino com hipogonadismo hipogonadotrófico associado à Sela parcialmente vazia. Proveniente do hospital Coronel Mota, Boa Vista/RR, em acompanhamento no ambulatório de Endocrinologia para controle de diabetes e seguimento de nódulos da tireoide, o paciente queixa-se de redução da libido e disfunção erétil. A Ressonância Magnética solicitada após identificados os baixos níveis hormonais nos exames laboratoriais, confirmando a suspeita clínica de hipogonadismo, evidenciou hipófise com altura de até 0,3 cm, caracterizando uma sela túrcica parcialmente vazia. Foi optado, então, pelo tratamento do paciente com reposição de testosterona. Conclusão: Apesar do diagnóstico dessa síndrome ser evidenciado incidentalmente na maioria das vezes, a associação com distúrbios hormonais torna necessário o rastreio rotineiro dessas alterações nos portadores assintomáticos para que o tratamento seja precoce, evitando-se complicações a curto e longo prazo.
Copaíba (Copaifera sp.): uma revisão bibliográfica sobre suas propriedades terapêuticas
Authors: Zambonin Fernanda , Lima Karen Ludimylla Bezerra , Maciel Jackeline da Costa , Dias Germana Bueno
Published: February 2023

Introdução: Ao longo do tempo, produtos de origem vegetal formaram o alicerce para o tratamento de doenças. A Copaifera sp é considerada uma das plantas medicinais mais estudadas em todo o mundo, destacando-se as pertencentes do gênero Copaifera sp. A Copaifera sp.tem uma extensa e tradicional aplicação como anti-inflamatório, antisséptico, cicatrizante, antimicrobiano e outras recomendações. Métodos: Trata-se de um estudo de revisão bibliográfica, realizado através de uma pesquisa nas bases de dados online. Para esse levantamento, utilizaram-se palavras-chaves e para a seleção, consideraram-se os títulos, os objetivos e os resultados dos artigos científicos. Desenvolvimento: Com relação ao levantamento bibliográfico, foram encontrados, no total, 153 artigos científicos publicados, sendo 57 para os descritores propriedade terapêutica e copaíba e 96 mediante propriedade terapêutica e Copaifera sp. A partir da pré-leitura para verificar se correspondiam aos critérios de inclusão e exclusão, obteve-se uma amostra de 15 artigos. Destes, destacam-se os artigos que apresentam alguma propriedade antimicrobiana, antineoplásico, ação no sistema gastrointestinal e com efeitos cutâneos. Conclusão: Com base na presente revisão de literatura foi possível identificar inúmeras propriedades terapêuticas do oleorresina de copaíba, ficando inegáveis seus benefícios. Entretanto, constatou-se uma quantidade limitada de pesquisas sobre suas propriedades medicinais nos últimos vinte anos e, a necessidade de pesquisas para averiguar os benefícios da sua aplicação em humanos.
Síndromes hipertensivas na gravidez: revisão integrativa
Authors: Casimiro Cintia Freitas , Oliveira Jadila Tainá Santos , Pereira Kelly Amanda Coelho , Bezerra Nayara Kalila Santos , Oliveira Sara Suerda Lopes
Published: February 2023

Introdução: A investigação das condutas profissionais realizadas no pré-natal e puerpério às mulheres que apresentam alguma patologia hipertensiva na gestação tem por finalidade minimizar os riscos de desfechos desfavoráveis, como complicações obstétricas e neonatais. Nesse contexto, objetivou-se investigar as evidências disponíveis na literatura acerca do conhecimento científico produzido sobre as condutas profissionais realizadas durante o pré-natal e puerpério às mulheres com alguma patologia hipertensiva diagnosticada na gestação. Métodos: Trata-se de uma revisão integrativa de literatura, que utilizou 8 artigos das bases de dados Medical Literature Analysis e Literatura Latino-Americana e do Caribe em Ciências da Saúde, publicados em português entre os anos de 2008 a 2018, ligados ao tema proposto. Desenvolvimento: Os resultados apontam que há evidências científicas relacionadas ao tratamento não medicamentoso, ao uso do sulfato de magnésio, ao uso da dexmedetomidina, e ao uso de hidralazina e metildopa. Conclusão: O levantamento dos estudos reforça a importância das orientações feitas pelo profissional de saúde na prevenção e controle das síndromes hipertensivas na gestação, além do seu conhecimento técnico-científico na utilização da terapia medicamentosa mais adequada para cada caso.
Síndrome da dor femoropatelar e tratamento conservador: uma revisão integrativa
Authors: Alecrim Joao Victor da Costa
Published: February 2023

Introdução: A síndrome da dor femoropatelar é um problema que atinge uma parcela significativa da população em especial jovens e adultos, seu sintoma principal é dor na parte anterior do joelho. O tratamento conservador é uma forma não cirúrgica de reabilitar o problema. Métodos: Foi feita uma revisão na base de dados MEDLINE e PUBMED com os seguintes descritores “Patellofemoral Pain Syndrome” AND “Treatment” OR “Rehabilitation”. Desenvolvimento: Observou-se que um programa de treinamento de fortalecimento do joelho somado a um programa de fortalecimento do quadril mostrou-se mais eficaz na redução de dor e aumento da autonomia, percebeu-se também que o uso de órteses é uma alternativa eficaz, principalmente quando se trata de correções biomecânicas. Conclusão: É necessário conhecer a causa do problema para que possa corrigi-lo da melhor maneira, então é de responsabilidade do profissional analisar e trabalhar com ferramentas baseadas em evidências a melhor forma de reabilitar o paciente
Efeitos fisiológicos e hormonais do treinamento concorrente na diminuição da sarcopenia em idosos – uma revisão de literatura
Authors: Sossai Mariana Ignácio , Conceição Luciana Renat , Canciglieri Paulo Henrique , Breda Leonardo
Published: February 2023

Introdução: A sarcopenia caracteriza-se pela diminuição gradativa de massa muscular pelo envelhecimento, alterando a funcionalidade musculoesquelética e desempenho físico relacionado ao movimento humano. Ademais, outros distúrbios são identificados: aumento do estresse oxidativo e adipócitos intramusculares, diminuição na síntese proteica, alterações sistêmicas e na integridade neuromuscular. A incidência no Brasil varia de 5 a 32% e essa doença se classifica em leve, moderada e severa. Objetivo: Nosso objetivo foi identificar os efeitos fisiológicos e hormonais advindos do treinamento concorrente nestes idosos e verificar a efetividade desse treinamento. Métodos: Todos os processos realizados acataram os princípios do Comitê de Ética em Pesquisa da FHO para pesquisa de revisão bibliográfica, inscrito sob o número CEP 047/2018 e foram desenvolvidos baseados em estudos encontrados nas plataformas Scielo, PubMed e Google Acadêmico, utilizando as seguintes nomenclaturas: “sarcopenia”, “idosos” e “treinamento concorrente”, “efeitos fisiológicos” e “hormônios” e depois selecionando apenas os estudos pertinentes ao tema da pesquisa. Desenvolvimento: O treinamento físico é essencial e atua como elemento coadjuvante ou principal no tratamento da sarcopenia, dependendo se há intervenção farmacológica ou não. Uma das metodologias de treinamento físico utilizadas nessa população é o treinamento concorrente – junção de exercícios resistidos e exercícios aeróbios, de caráter dinâmico e intervalado, promovendo várias adaptações fisiológicas positivas para este público. Conclusão: O treinamento concorrente é positivo no combate da sarcopenia e suas causas, possibilitando ao paciente um acervo de benefícios morfológicos, fisiológicos e hormonais que permitirão aumento da qualidade de vida e autoestima social.
Perfil clínico-epidemiológico de pacientes cirróticos internados em hospital público de referência do estado de Roraima
Authors: Oliveira Jérula K. L. de , Figueiredo Virgínia M. , Oliveira Karla C. L. de , Alkas Pedro G. de C. , González Yany L. L.
Published: February 2023

Introdução: A cirrose hepática é uma doença evitável multifatorial, considerada a principal doença crônica do fígado e associada a aumento da morbimortalidade e reduzida qualidade de vida. Objetivo: Caracterizar o perfil clínico-epidemiológico de pacientes internados com cirrose hepática no Hospital Geral de Roraima. Métodos: Estudo observacional, retrospectivo, de revisão de 37 prontuários de pacientes com diagnóstico de cirrose hepática que foram internados no Hospital Geral de Roraima - Boa Vista-RR no período de 01 de janeiro de 2017 a 31 de dezembro de 2017. Resultados: A idade média foi de 54,2 anos, sendo a amostra composta predominantemente por homens (68%) e etnia parda (78%). Etiologias mais comuns: álcool em 41%, vírus da hepatite C (VHC) em 14%, álcool + VHC em 5% e álcool + vírus da hepatite B (VHB) em 5% das internações. As hospitalizações ocorreram por hemorragia digestiva alta (HDA) em 33%; encefalopatia hepática (EH) em 32%; e ascite em 21%. A duração média das internações foi de 11,5 dias. Classificação Child-Pugh A em 2%, B em 14% e C em 54% dos casos. A taxa de mortalidade em 1 ano foi de 70%, decorrente em 38% dos casos de infecções (pulmonares, peritonite bacteriana espontânea, dentre outras). Dos 19 pacientes que sobreviveram à primeira internação, 74% reinternaram em 1 ano. Conclusão: A principal etiologia da cirrose foi o alcoolismo, seguido da infecção pelo VHC. As internações ocorreram por HDA, EH e ascite, com taxa de reinternação de 74% e mortalidade de 70% em 1 ano.