bluuebunny/crossref_metadata_2025 huggingface dataset:
SURGICAL TREATMENT OF SCARS OF THE HEAD AND NECK BY THE METHOD OF EXCISION USING ROTARY FLAPS
Authors: Shaprynskyi V. O. , Mikhurinskyi D. V. , Kobiakov O. V.
Published: January 2024

Abstract. Soft tissue injuries of the head and neck are a fairly common pathology that has a number of negative consequences - both psycho-emotional and functional in nature. As a result, scars are formed, which can provoke a number of functional complications, such as limitation of mobility, discomfort during movements, paresthesia, contracture, loss of sensitivity. The article presents the optimal method of surgical treatment of hypertrophic scars on the flexural surfaces of the head and neck.

Goal. To improve the results of surgical treatment of patients with scars on the flexural surfaces of the head and neck by using rotary flaps.

Conclusions. The method of sharp excision of the scar with rotational flaps is quite effective for existing hypertrophic scars in the flexural areas of the neck. Moving the scar to a more natural anatomical plane - horizontal, makes it possible to avoid tension during rotational movements. The use of a natural furrow of the skin - provides a masking and aesthetic effect.
The New Partnership for African Development (NEPAD), Profits and Poverty: Historicizing A Persisting Dilemma
Authors: Okoko Charles Okeke , Mgbowaji Benson Romokere
Published: January 2024

This paper surveyed the New Partnership for African Development (NEPAD), its agenda, strength and weaknesses vis-à-vis the raison d’etre for its establishment. It appraised the gains accruing to Africa in contradistinction to that of the developed world which discerned a yearning disparity. For Tony Blair (a former British Prime Minister), this partnership was not just about aid in its totality, it was not only about what we give, Africa needed our support and we needed Africa to succeed. It was how altruistic the likes of Tony Blair were that necessitated the review of the activities of NEPAD and its effect on Africa that claimed its patent. This was against the background of a persisting underdevelopment, especially the economic, of African countries and the poverty of their citizens. The manipulative operations of International Financial Institutions (IMF, World Bank-IBRD, among others) opened up African economies to exploitation with the unarguable connivance of rich multinational corporations and consultancy firms who maximized their profits from Africa’s misery and helplessness. The paper concluded that Western corporate power in Africa was a monster with a thousand stomachs, insatiable for profits. For Africans, this was a hard stuff to swallow - but corporate greed knew no limits. The comparative and the analytical were adopted.
ALBERT CAMUS: O ESTRANGEIRO NA FILOSOFIA ABSURDA DA EXISTÊNCIA
Authors: Araújo Antônio Carlos , Araújo Sebastiana Luciana Ferreira
Published: January 2024

Objetivo: Este capítulo visa explorar as ideias filosóficas de Albert Camus, focando especialmente em sua obra seminal "O Estrangeiro". Buscamos compreender como Camus aborda a existência humana, destacando seu conceito de absurdo e a revolta como resposta. Método: Adotamos uma abordagem analítica, começando por contextualizar as origens das ideias de Camus, moldadas por sua vivência na Argélia colonial. Em seguida, mergulhamos na narrativa de "O Estrangeiro", explorando as personificações do absurdo através do protagonista Meursault. Além disso, examinamos outras obras-chave, como "O Mito de Sísifo", para enriquecer a compreensão da filosofia camusiana. Resultados: Nossos resultados destacam a visão camusiana do absurdo como uma tensão entre a busca humana por significado e um universo aparentemente indiferente. A figura de Meursault em "O Estrangeiro" é explorada como uma metáfora viva desse absurdo, enquanto a revolta é apresentada como a resposta autêntica de Camus à condição absurda da existência. Conclusão: Encerramos o capítulo ressaltando a ousadia de Camus em confrontar diretamente o absurdo da existência humana. Salientamos que, para Camus, a busca por significado não reside em respostas definitivas, mas na coragem de viver plenamente consciente do paradoxo da vida. Convidamos o leitor a aprofundar-se na complexidade do pensamento camusiano, desafiando as convenções filosóficas tradicionais ao encontrar significado na própria revolta contra o absurdo.
Álbum Familiar de Madrigueras
Authors:   Madrigueras y sus raíces
Published: January 2024

La pasión por las fotos antiguas y el cariño a nuestro pueblo fue el catalizador que unió a Enrique Cabañero Hernández, Isabel Fuentes Paños (in memoriam), José María García García, Pilar Garrido Paños, Antonio Gómez Paños, María Ibáñez Milla, Paquita Martínez García y Teodora Monsalve Catalán, para iniciar en Facebook el proyecto “Madrigueras y sus raíces”. Cuando creamos la página de fotos antiguas en octubre de 2018, no imaginábamos la enorme repercusión que iba a tener en nuestros paisanos. Cada día nuevos vecinos solicitaban unirse a la página. Viendo la gran acogida, nos atrevimos a ir llamando a las puertas para buscar desde las fotos más antiguas y emblemáticas hasta los tiempos no tan lejanos de los 90. Ahora contamos con más de 400 fotos.
Investigation of Two-Way Fluid-Structure Interaction of Blood Flow at Different Temperature using CFD
Authors: Mohsen Jweeg  , Emad Qasem Hussein  , Farhan Lafta Rashid  , Ali Basem
Published: January 2024

At this work, fluid-structure interaction was used to biomechanical challenges relating to blood flow in artery bifurcation to investigate potential solutions. The purpose of this study was to evaluate the influence that artery geometry has under constant flow, pulsatile flow, and varied blood temperatures. In this study, the flow of blood through the artery was simulated using a non-Newtonian fluid model, and the finite element technique was utilized to analyse the data. For the purpose of analysing the differences between pulsatile flow and steady flow, a user-defined function, or UDF, was developed as part of the suggested input velocity model. In order to accurately estimate the pressure distribution, velocity flow, wall shear stress, and wall deformation, a simulation called ANSYS 17.2 is used to model the fluid-structure interaction that occurs when blood flow is superimposed on an arterial wall. According to the findings, the pressure amplitude steadily increases in the artery zone for high temperatures, demonstrating that the projected pressure is 15% greater than it was when the temperature was low. This is in contrast to the low temperature, for which the predicted pressure was 15% lower. In addition, the area close to the apex has the highest levels of shear stress, which then drop down precipitously farther along the wall until they reach an almost constant level. In general, the location of maximum total deformation is shown at peak systole for the artery when the temperature is high. This is the location where the pressure is high, particularly at the artery bifurcation, and where there is a maximum wall deformation of 0.447 mm. In addition, this is the location where the maximum total deformation occurs. These findings are of great use in the design of arterial bifurcation as well as the assessment of recurrent mechanical loads, both of which contribute to the prediction of life.
The Effect of Overconfidence and ESG level on Investment Efficiency
Authors:   Academic Society of Global Business Administration, Sim Jae Woo
Published: January 2024

I would like to examine how management and overconfidence caused by ESG activities, which are issues among recent management techniques, affect investment decisions made by managers with strong overconfidence tendencies. This study analyzed whether CEO overconfidence affects investment efficiency according to ESG ratings. Overconfidence was measured based on the research of Schrand and Zechman(2012) and Ahmed and Duellman(2013), and investment efficiency was measured based on the research of Biddle et al.(2009). The study period is from 2013 to 2022, and the total number of samples is 6,298, and the results are as follows.
First, overconfidence has a positive effect on investment efficiency, which means that the stronger the overconfidence tendency, the more inefficient it appears in investment efficiency.
Second, ESG ratings have a negative effect on investment efficiency, which means that the higher the ESG rating, the more efficient the company's investment appears.
Third, it was confirmed that overconfidence is alleviating investment inefficiency caused by overinvestment due to the high ESG rating. Companies with high ESG ratings have found that investment inefficiencies are mitigated even though managers have a strong tendency to over-line.
This study is expected to contribute to prior research by analyzing the impact of overconfidence propensity on investment efficiency according to ESG ratings and providing evidence that it may vary depending on detailed grades.
Influencer marketing kao izvrstan način promocije poljoprivrednog proizvoda
Authors: Mandušić Dubravka , Katalinić Veronika , Blašković Lucija
Published: January 2024

Influenceri ili utjecajnici su osobe koje na raznim društvenim mrežama poput Instagrama, Facebooka, Twittera, svojim životnim stilom, ponašanjem i stavom snažno utječu na osobe koje ih prate. Influenceri su osobe sveprisutne u svakodnevnim životima osoba koje ih prate, često djeluju kao dio marketinških kampanja čime mogu utjecati na ponašanje pratitelja koji u njih imaju povjerenje. Infiltrirani su danas u sve djelatnosti pa tako i u poljoprivredu. U poljoprivrednom sektoru mogu uspješno promovirati razne brendove te tako pomoći u promidžbi i prodaji proizvoda. Influencer marketing bi trebao poznavati svaki vlasnik malog ili velikog gospodarstva i stjecanjem tog znanja odrediti koji influencer bi bio idealan za suradnju i kako bi suradnja trebala izgledati. Promocija na internetskim blogovima i društvenim mrežama u kratkom roku može privući velik broj kupaca i klijenata koji donose profit. Cilj ovog rada je pokazati koliko je danas reklamiranje čak i poljoprivrednih proizvoda, preko javih osoba putem društvenih mreža popularno u cjelokupnom proizvodnom procesu, kako u svijetu tako i u Hrvatskoj.
ASSESSMENT OF GROUNDWATER QUALITY FOR IRRIGATION PURPOSE USING IRRIGATION WATER QUALITY INDEX (IWQI)
Authors: Al-Aizari Hefdhallah S. , Aslaou Fatima , Mohsen Osan , Al-Aizari Ali R. , Al-Odayni Abdel-Basit , Abduh Naaser A. Y. , Al-Aizari Abdul-Jaleel M. , Abo Taleb Eman
Published: January 2024

Groundwater represents an important natural resource for sustaining life. This study was conducted to evaluate groundwater in the Doukkala region in Morocco, using the Irrigation Water Quality Index (IWQI) and uses Inverse Distance Weighting (IDW) in GIS was to show the spatial distribution of water quality parameters. It collected 97 of samples from groundwater and were estimated the sodium concentration (Na%), and sodium absorption rate (SAR), Also, Residual sodium carbonate (RSC), Kelly index (KI), magnesium content (MR), salinity potential (PS), and permeability index (PI). According to the distribution map of the Irrigation Water Quality Index (IWQI) for the study area, about 22.7% of samples fall into the severe restriction (SR) category, which can be used to irrigate plants with high salinity tolerance, 34.02 of samples fall under the high restriction (HR) category, 23.7% of samples fall into the moderate restrictions (MR) category, 17.52% of samples fall under the low restriction (LR) category, and 2.06% of samples fall under the no restriction (NR) category. The results of (IWQI) indicated that the groundwater quality in the study area is mostly suitable for irrigation purposes.
Molecular docking screening, dynamics simulations, ADMET, and semi-synthesis prediction of flavones and flavonols from the COCONUT database as potent bifunctional neuraminidase inhibitors
Authors: Ha Thi-Kim-Quy , Pham-Khanh Nguyen-Huan , Nguyen Thanh-Khiet
Published: January 2024

Finding new neuraminidase (N) inhibitors to improve anti-influenza treatment is necessary because of the high mutation rates of N protein. Over 3,000 flavones/flavonols and their synthesized products from the COCONUT database were performed in silico docking screening with N1-H274Y-oseltamivir protein (PDB ID: 3CL0). Several derivatives containing nitrogen heterocyclic groups or aromatic rings showed higher anti-neuraminidase potential than that of laninamivir. Especially, the linker groups between the flavone aglycone and nitrogen heterocyclic group created the interactions with the triad of arginine residues Arg118-Arg292-Arg371, which suggested these compounds could become bifunctional inhibitors against the influenza virus strains at the sialic acid binding site and the adjacent 430-cavity position through triad of arginine residues binding. ADMET indicators and the synthesis design strategy of the most suitable compound, ethyl 4-{2-[(5-hydroxy-4-oxo-2-phenyl-4H-chromen-7-yl)oxy]acetyl}piperazine-1-carboxylate, were also successfully predicted and it could be a concerned candidate for further wet-lab synthesis, in vivo and clinical study.
Assessing Associations Between Health Information Technology Maturity and Nursing Home Survey Deficiencies
Authors: Alexander Gregory L. , Liu Jianfang
Published: January 2024

One in three nursing home (NH) residents experience adverse events. One strategy for safer NH care is health information technology (HIT). Two national NH surveys measuring HIT maturity were administered in 2020 (
N
= 719) and 2021 (
N
= 312). Quarterly NH survey deficiencies from the same years were linked to HIT maturity surveys. Descriptive statistics and logistic regression were used in analysis. NHs were of similar size and location, with more for-profit facilities. Most (67.5% and 61.9%, respectively) NH administrators reported having capabilities to share data internally within their facility, and not externally. Mean HIT maturity scores increased from Year 1 to Year 2. Over 2 years, 5,406 deficiencies were reported, mostly (31.3%) for nutrition and dietary deficiencies. There were negative associations between HIT maturity and deficiency scope. With a 1-unit increase in HIT maturity, relative risk of widespread scope decreased by 14%. Among covariates, bed size, staffing, and year were significant factors associated with deficiency scope. [
Journal of Gerontological Nursing, 50
(1), 8–14.]
QoS-driven resource allocation in fog radio access network: A VR service perspective
Authors: Lv Wenjing , Chen Jue , Cheng Songlin , Qiu Xihe , Li Dongmei
Published: January 2024

While immersive media services represented by virtual reality (VR) are booming, They are facing fundamental challenges, i.e., soaring multimedia applications, large operation costs and scarce spectrum resources. It is difficult to simultaneously address these service challenges in a conventional radio access network (RAN) system. These problems motivated us to explore a quality-of-service (QoS)-driven resource allocation framework from VR service perspective based on the fog radio access network (F-RAN) architecture. We elaborated details of deployment on the caching allocation, dynamic base station (BS) clustering, statistical beamforming and cost strategy under the QoS constraints in the F-RAN architecture. The key solutions aimed to break through the bottleneck of the network design and to deep integrate the network-computing resources from different perspectives of cloud, network, edge, terminal and use of collaboration and integration. Accordingly, we provided a tailored algorithm to solve the corresponding formulation problem. This is the first design of VR services based on caching and statistical beamforming under the F-RAN. A case study provided to demonstrate the advantage of our proposed framework compared with existing schemes. Finally, we concluded the article and discussed possible open research problems.
Anoikis-related mRNA-lncRNA and DNA methylation profiles for overall survival prediction in breast cancer patients
Authors: Yang Huili , Qiu Wangren , Liu Zi
Published: January 2024

As a type of programmed cell death, anoikis resistance plays an essential role in tumor metastasis, allowing cancer cells to survive in the systemic circulation and as a key pathway for regulating critical biological processes. We conducted an exploratory analysis to improve risk stratification and optimize adjuvant treatment choices for patients with breast cancer, and identify multigene features in mRNA and lncRNA transcriptome profiles associated with anoikis. First, the variance selection method filters low information content genes in RNA sequence and then extracts the mRNA and lncRNA expression data base on annotation files. Then, the top ten key mRNAs are screened out through the PPI network. Pearson analysis has been employed to identify lncRNAs related to anoikis, and the prognosis-related lncRNAs are selected using Univariate Cox regression and machine learning. Finally, we identified a group of RNAs (including ten mRNAs and six lncRNAs) and integrated the expression data of 16 genes to construct a risk-scoring system for BRCA prognosis and drug sensitivity analysis. The risk score's validity has been evaluated with the ROC curve, Kaplan-Meier survival curve analysis and decision curve analysis (DCA). For the methylation data, we have obtained 169 anoikis-related prognostic methylation sites, integrated these sites with 16 RNA features and further used the deep learning model to evaluate and predict the survival risk of patients. The developed anoikis feature is demonstrated a consistency index (C-index) of 0.778, indicating its potential to predict the survival probability of breast cancer patients using deep learning methods.
Urban Heat Islands in Tirana, Albania - Analysis and Potential Solutions
Authors: Aimar Fabrizio , Xhexhi Klodjan
Published: January 2024

Cities and towns are expanding and thriving as a result of urbanization, which also significantly changes the local climate. One of the most significant phenomena associated with urbanization is the Urban Heat Island (UHI) effect. This phenomenon is increasingly being studied worldwide. The paper aims to investigate the UHI phenomenon in the metropolitan area of Tirana, Albania. It analyses the impact of the UHI on four specific locations in Tirana, its causes and mitigation measures, as well as variations in surface temperature, CO2 emissions, and relative humidity. The regions are measured and observed using a specific instrument such as the Testo 435. Considering the mean surface temperature variations between urban and rural regions ranging from 28.4°C to 33.7 °C, CO2 emissions from 302.9 ppm to 416.2 ppm, and relative humidity from 34.1% to 41.2%, it is found that the UHI impact in Tirana is significant. The lack of green spaces, high building density, urban patterns, building materials used, transport, and energy use are the main contributors to the UHI in central Tirana. Increasing green spaces, using reflective materials, and promoting sustainable urban design are some of the mitigation techniques suggested to reduce the UHI effect in Tirana.
Financial Literacy and its Determinants: A Case of Professionals in Colombo District Sri Lanka
Authors: Madhushani P. W. G. , Rajapakse R. P. C. R.
Published: January 2024

This observation intends to examine the financial literacy level of professionals working in the professions of Medicine (Doctors), Engineering (Engineers), Management (Managers), Law (Lawyers) inclusive Aviation and Navigation (Captains and Pilots), and its determinants. The methodology was a quantitative survey approach involving a sample of 300 respondents from the Colombo district. The analysis revealed that Basic and Advanced financial literacy among professionals is at a medium level. However, the level of financial literacy was not at a satisfactory level among non-management professionals, particularly doctors and lawyers. The results of the Regression analysis revealed that Economic and financial education, self-analytical skills, the field of employment, and monthly income level as influential determinants of financial literacy. The professions with less exposure to economic and financial education have low financial literacy. Findings demonstrate the growing importance of implementing a national strategy to improve financial and economic educational programmes, particularly for individuals who are not working in the professions related to management.
Newspaper depiction of mental illness in Nigeria
Authors: Erubami Joshua , Bebenimibo Paul , Ezeah Gregory , Muobike Omanwa
Published: January 2024

Mental illness is fast becoming a leading cause of global disease burden, yet this aspect of public health remains highly neglected in Nigeria. The public relies on newspapers for diverse information needs and the way newspapers portray mental illness‑related issues tends to sway public perception of such ailments. This study examined the level of media attention and prime discursive resources utilized by newspapers to depict mental illness‑related issues from 2015 to 2019. Using a qualita‑ tive approach and ethnographic design, the study analyzed the manifest contents of three major Nigerian national newspapers selected through a multistage sampling technique. Data collec‑ tion was done using a coding spreadsheet that reflected relevant content categories and units of analysis. Of the 920 health articles analyzed, only 79 (8.6%) articles discussed mental illness. Also, 84.8% of all mental illness‑related articles were tucked in the inside pages of the newspapers and 58.2% of the stories were reported using the conventional straight news. The negative themes of suicide (36.7%) and substance abuse (32.9%) were the prime discursive resources that echoed in many of the analyzed articles. Overall, mental illness‑related issues were grossly under‑reported by Nigerian newspapers when compared to other health issues, and wrong media depiction of the problem remains a risk factor. Hence, Nigerian newspapers must strive toward setting better agenda that will actuate necessary policy actions from health stakeholders by providing adequate coverage and positive representation of mental illness‑related issues.
Expectations and experiences of urban and rural in‑school adolescents of adolescent reproductive health services in Oyo State
Authors: Ilori Oluwatosin R. , Olarewaju Sunday O. , Awodutire Phillip O. , Ilori Oluwatosin S. , Bamidele James O.
Published: January 2024

Reproductive health information and services are fundamental to health, well‑being and opportunities for women and young people, yet throughout the world, women and youths do not have access to quality reproductive health care thereby exposing them to unplanned pregnancy, teen birth, induced abortion as well as increased exposure to sexually transmitted diseases, HIV inclusive. This study is meant to explore the expectation of adolescents of an adolescent reproductive health services as well as to assess the experiences of those who had visited an ARHS at the centers. It was a descriptive cross‑sectional prospective study, analytic in design using a multistage sampling technique where 452 secondary school pupils in both rural and urban communities were interviewed using a pretested validated questionnaire. Data was analyzed using SPSS version 21. Chi square was used to test for association between both rural and urban adolescents in issues relating to their expectation and experiences, with P‑value of 0.05. More of the respondents in the urban communities (73,32.4%) have the expectation that Adolescent Reproductive Health Services (ARHS) should be provided in an existing health service with special attention to adolescents while a larger percentage of those who preferred a special adolescent health institution were from the rural communities (122, 54.2%) which was statistically significant with a P‑value of 0.001. More of respondents from the rural communities also expect that contraception services should be provided in an ARHS center while life skill services are expected by more of the respondents from the urban communities (122, 55.6%). More of the rural community respondents (57,25.3%) expect that fee at the ARHS centers should be provided at a subsidized rate while more of the urban dwellers have the expectation that services provided should be free of charge. For respondents who had been to an ARHS center, more of the urban respondents were attended to by a Medical doctor and a large percentage (34,94.4%) of those who had visited ARHS center before professed to be satisfied with the services rendered there. Expectations from adolescents from ARHS are very high. However, most of them prefer a free of charge service as well as a service area nearer to residential area. Confidentiality and having a young health professional at the service centers cannot be overempha‑sized in the provision of quality ARHS.
SARS‑CoV‑2 IgG antibody status in unvaccinated and 2‑dose vaccinated Indonesians by Astra Zeneca
Authors: Yamani Laura , Juniastuti Juniastuti , Megasari Ni L.A. , Utsumi Takako , Sahila Nur , Pangestika Alifia S. , Putri Serius M.D. , Yi Li Chung , Martini Santi , Isfandiari Muhammad A. , Lusida Maria I.
Published: January 2024

Indonesia began deploying a COVID‑19 vaccine in January 2021, prioritising vaccination for high‑risk groups such as healthcare workers, the elderly and those with comorbidi‑ ties, and ending with the general public due to limited vaccine availability. Our study aimed to evaluate antibody response in Indonesians who had received two doses of the vaccine vs. those who had not. The study design was a cohort study involving 46 unvaccinated people and 23 people who had received the second dose of the AstraZeneca vaccine in three months. Methods used for the qualitative and quantitative detection of IgG antibodies included rapid RI‑GHA and ELISA tests. Findings showed that positive IgG antibodies qualitatively detected by the rapid RI‑GHA test were significantly higher in those vaccinated (60.9%) than in unvaccinated people (26.1%). Using the ELISA assay, all vaccinated individuals qualitatively showed positive antibodies (cut‑off ≥4.33 BAU/ml), and the average quantitative titer of anti‑SARS‑CoV‑2 s‑RBD IgG was significantly higher in vaccinated (157.06±238.68 BAU/ml) than in unvaccinated (51.90±87.60 BAU/ml) individuals. Some unvaccinated individuals with no history of infection were found to have anti‑SARS‑CoV‑2 antibodies that may have been previously asymptomatic, although their mean antibody titers were certainly lower than those in the 2‑dose group. Approximately 56% of vaccinated individuals had antibody titers above 60 BAU/ml as a cut‑off for protective threshold, a significantly higher proportion than unvaccinated individuals. In conclusion, vaccination with two doses AstraZeneca increased anti‑SARS‑CoV‑2 antibodies which resulted in enhanced immunity against symptomatic COVID‑19.
Mapping the pandemic: a review of Geographical Information Systems‑based spatial modeling of Covid‑19
Authors: Aboalyem Mustafa S. , Ismail Mohd T.
Published: January 2024

According to the World Health Organization (WHO), COVID‑19 has caused more than 6.5 million deaths, while over 600 million people are infected. With regard to the tools and techniques of disease analysis, spatial analysis is increasingly being used to analyze the impact of COVID‑19. The present review offers an assessment of research that used regional data systems to study the COVID‑19 epidemic published between 2020 and 2022. The research focuses on: categories of the area, authors, methods, and procedures used by the authors and the results of their findings. This input will enable the contrast of different spatial models used for regional data systems with COVID‑19. Our outcomes showed increased use of geographically weighted regression and Moran I spatial statistical tools applied to better spatial and time‑based gauges. We have also found an increase in the use of local models compared to other spatial statistics models/methods.
The health benefits of rooibos tea in humans (aspalathus linearis)‑a scoping review
Authors: Afrifa Daniel , Engelbrecht Louise , Op't Eijnde Bert , Terblanche Elmarie
Published: January 2024

Natural remedies in the treatment of health condi‑ tions are an appealing option for many individuals. Previous studies reported that fermented and unfermented rooibos tea have considerable anti‑inflammatory and antioxidative properties. Most of this knowledge, however, originates from animal and cell culture studies. The aims of this review are to evaluate the existing, but limited, body of knowledge regarding rooibos tea interventions in humans and to iden‑ tify the gaps in the literature. The PRISMA extension for Scoping Reviews (PRISMA‑ScR) guidelines were followed in the collation of this scoping review. Among the databases searched were Google Scholar, PubMed, Cochrane Library, Scopus, and Web of Science. This review comprised 18 publications, with half (50%) of the studies being conducted in South Africa. There were 488 participants in all, ranging in age from six to 83 years, in the investigations. Rooibos tea was either fermented, unfermented, or black in 62% of the studies. Doses ranging from 200 to 1,200 ml were employed. In both healthy and at‑risk individuals, rooibos has been shown to enhance lipid profiles, boost antioxidant status, and lower blood glucose levels. The existing findings suggests that rooibos consumption demonstrated to improve lipid profiles, boost antioxidant status, and lower blood glucose levels in both apparently healthy, and individual at‑risk individuals or diagnosed of chronic conditions. Thus, it can be presumed that rooibos tea provides some health benefits, yet these findings are based on a limited number of human intervention studies and a small total sample size. Additionally, a variety of rooibos dosages and types of tea in the experiments had inconsistent results that were probably impacted by the amount consumed. Future studies should include a dose‑response study in humans, as well as large scaled clinical trials to evaluate the health effects of Rooibos.
Drug Repositioning of Pioglitazone in Management and Improving the Cognitive Function among the Patients with Mild to Moderate Alzheimer's Disease
Authors: Basutkar Roopa S. , Sudarsan Pooja , Robin Sandra M. , Bhaskar Vahini , Viswanathan Balasubramaniam , Sivasankaran Ponnusankar
Published: January 2024

Background:

Disease-modifying agents like Pioglitazone have shown promising effects on neuroinflammation and homeostasis of amyloid plaques, but there is a lack of research papers providing conclusive evidence.

Objectives:

This study is aimed to determine the safety and efficacy of Pioglitazone in improving cognitive function in patients with mild-moderate Alzheimer's disease (AD).

Materials and Methods:

Trials published in the last 12 years were identified from PubMed, Scopus, Cochrane Central, and other trial registries. Five hundred twenty-five records were obtained, from which five studies were included for quantitative analysis. Studies comparing Pioglitazone with a suitable placebo or other oral hypoglycemic agent were considered for review. Data was extracted using a pretested form, which was followed by a risk of bias assessment (ROB) with Cochrane's ROB assessment tool.

Results:

This meta-analysis included studies where Pioglitazone (15–30 mg) was compared to other oral hypoglycemic agents, placebo, or diabetic diet for a minimum duration of 6 months. Pioglitazone did not show a statistically significant improvement in Alzheimer's Disease Assessment Scale-Cognitive Subscale (ADAS-Cog) scores [mean difference (MD): −1.16; 95% confidence interval (CI): −4.14–1.81]. By conducting sensitivity analysis with the removal of one study, significant efficacy was obtained [MD: −2.75; 95% CI: −4.84–−0.66]. The Wechsler Memory Scale-Revised logical memory I (WMS-R) scores had a significant improvement in the Pioglitazone group [MD: 2.02; 95% CI: 0.09–3.95].

Conclusion:

Pioglitazone is a safe medication that has a promising effect in slowing the advancement of AD.
Systems involving mean value formulas on trees
Authors: Miranda Alfredo , Mosquera Carolina A. , Rossi Julio D.
Published: January 2024

In this paper, we study the Dirichlet problem for systems of mean value equations on a regular tree. We deal both with the directed case (the equations verified by the components of the system at a node in the tree only involve values of the unknowns at the successors of the node in the tree) and the undirected case (now the equations also involve the predecessor in the tree). We find necessary and sufficient conditions on the coefficients in order to have existence and uniqueness of solutions for continuous boundary data. In a particular case, we also include an interpretation of such solutions as a limit of value functions of suitable two-players zero-sum games.
Italo Calvino et Jacques Probst : nourriture comme propulseur textuel (déploiement structurel et déploiement diffus d’un thème littéraire)
Authors: Wołowski Witold
Published: January 2024

Italo Calvino and Jacques Probst: food as a textual propulsor (structural deployment and diffuse deployment of a literary theme)

This article analizes the theme (motif) of food in Un navire chargé de..., a folk tale rewritten by Italo Calvino and Lise, l’île by Jacques Probst. The Italian tale and the Suiss monologue actually represent two different ways of using food elements in the construction of a text. The first uses the thematic elements in a punctual way, in the crucial moments of the action which correspond to the strong points of the fable; this strategy is called structural deployment of the thematic cluster. The second text, exploiting the absence of food, involves food elements over its entire extent and at different levels of its structure, what we call diffuse deployment (of the thematic cluster).
Natura(lnie) w Zabrzu – dobre ekopraktyki projektowe
Authors: Foltyn-Simka Anna , Koenigshaus Anna , Kot Sylwia , Krulicka Katarzyna
Published: January 2024

Projekt ekologiczny „Natura(lnie) w Zabrzu” stanowi odpowiedź na pogłębiający się kryzys klimatyczny i wciąż rodzącą się edukację ekologiczną w szkole. Prowadzony przez cztery nauczycielki z Zabrza projekt wpisuje się w edukację interdyscyplinarną i włączającą, kształtuje aktywne postawy prospołeczne i daje uczestnikom poczucie sprawczości. Inicjatywy z im związane obejmują współpracę między szkołami oraz instytucjami miejskimi i ośrodkami naukowymi, dzięki czemu projekt zyskuje coraz większy zasięg. Podejmowane działania pozwalają na poszerzanie wiedzy w zakresie problemów ekologiczno-klimatycznych oraz wypracować prośrodowiskowe nawyki. W artykule przedstawione są praktyczne rozwiązania metodyczne i dydaktyczne, które organizatorki stosują w ramach projektu „Natura(lnie) w Zabrzu”.
Społeczeństwo obywatelskie w rozumieniu uczniów krakowskich szkół średnich
Authors: Trzópek- Paszkiewicz Joanna , Ulatowska Roksana
Published: January 2024

The main objective of the present study is to learn about the understanding of civil society among the students of Kraków’s econdary schools. A school is an institution that, apart from teaching and creating space for students’ learning, performs other social functions, including socialisation and development of subjectivity. School is the first community in one’s social life that can be a space for the development of social, democratic and civic competences. The starting point is learning about students’ mental models regarding the construct of civil society. Qualitative research was conducted among 308 secondary school students from the city and Commune of Kraków. The young generation understands civil society as con-sisting of active citizens who create an engaged, independent, goal-oriented community. However, our research shows that this concept is understood differently and that this understanding needs to be debated and constructively discussed among young citizens. The authors also set a practical goal of developing recommendations for schools on how to support students’ civic articipation.
Regulation on the Utilization of Carbon Service as a Forest Protection Effort in Indonesia
Authors: Walid Siagian Abdhy , Syofiarti  , Rosari Anton
Published: January 2024

Reducing Emissions from Deforestation and Forest Degradation (REDD+) is a strategy to reduce greenhouse gas emissions from deforestation and forest degradation. Through this scheme, Indonesia is vital in implementing ratified commitments through national legislation. The methodology used in the research employed normative juridical techniques characterized by descriptive research parameters and underwent analysis through comprehensive literature exploration. The results found that Indonesia has supported sustainable development by issuing REDD+ arrangements to realize climate change mitigation. Through the REDD+ scheme, Indonesia is expected to provide answers to global warming problems that occur throughout the world by providing protection, preventing degradation, and providing an increase in the quality of forest cover and carbon stocks.
Exploring Sustainable Economic Growth: Promoting Green Development Productivity through Decentralized Environmental Policy and Regional Competitiveness
Authors: Fajri Moh Najikhul , Munawaroh Siti
Published: January 2024

The freedom of regions in regulating territories is now being promoted with the decentralization of environmental policies. This policy serves as the forerunner in empowering regions to function autonomously, thereby playing a role in practical politics. Therefore, this research aimed to analyze the role of decentralization of environmental policy and local government competition in navigating green development productivity in Indonesia. The slack base model and dynamic panel regression were used to generalize the method of the moment. The results showed that the decentralization of environmental policies and local government competition negatively affected the productivity of green development. Meanwhile, budget allocations for research and development, along with strategic initiatives in economic sectors such as agriculture and mining, showed a substantial positive effect.
Hibridez transcultural en la poesía neomística en lengua española. Una perspectiva a partir de casos recientes
Authors: Helgueta Manso Javier
Published: January 2024

Uno de los argumentos para poder hablar de un contexto postsecular es el mantenimiento de la religiosidad profana en sus manifestaciones estéticas. Como otros fenómenos culturales, la espiritualidad occidental se ha transformado por la digitalización, el transhumanismo y la aceleración de los intercambios transnacionales. Si Néstor García Canclini habla de ‘culturas híbridas’, creo que se debe utilizar el término ‘espiritualidades híbridas’; dentro de estas, se pueden apreciar neomisticismos híbridos en la poesía contemporánea. De hecho, considero que el sincretismo de esta poesía es una prueba para su resignificación como nueva mística. Aunque existen diferentes tipos de hibridación, en este trabajo voy a tratar la hibridez transcultural. Para ello, he establecido una clasificación dividida en cuatro tipos: 1. hibridez transcultural por razones de migración y reminiscencias del origen religioso; 2. hibridez transcultural y transtemporal: el rescate de sistemas perdidos; 3. hibridez transcultural a partir de tradiciones no originarias; 4. hibridez multitranscultural. Cada una de estas se ha estudiado, respectivamente, en poetas de hasta seis países de lengua española: David Rosenmann-Taub (Chile); Jorge Eduardo Eielson (Perú) y Eduardo Scala (España); Elsa Cross (México) y Vicente Gerbasi (Venezuela); Gloria Gervitz (México) y Ernesto Cardenal (Nicaragua). Se espera así demostrar la hipótesis inicial y presentar un método para el análisis de los neomisticismos híbridos de tipo transcultural en la poesía hispánica de nuestro tiempo, método que pueda ser mejorado en siguientes trabajos, así como refutado o sofisticado por la comunidad académica.
Institución y derecho en el giro normativo político deleuzeano: una lectura de la jurisprudencia como variación
Authors: Castro Serrano Borja , Fernández Ramírez Cristian
Published: January 2024

El esfuerzo moderno por articular Soberanía y Ley tiene por horizonte el tratamiento de lo institucional confinado a la estructura de la representación, desde la aplicación del derecho y la ley hasta la configuración de lo estatal. Se problematiza el plano representacional del Derecho y su implementación de leyes y derechos, para ampliar sus fronteras y cuestionar la operación de estas clásicas asociaciones. Se abre un camino fructífero para pensar una concepción del derecho y la jurisprudencia en relación con la teoría de la institución deleuzeana y su vínculo con lo social, tensionando al máximo el binomio ley-representación. La filosofía del derecho propuesta por Deleuze establece una base, en tanto práctica de casos singulares, que puede encarnarse en la propia idea de filosofía inmanente del francés. Hay un mundo a desenvolver en esta perspectiva del derecho como crítica a la Ley abriendo otra práctica legal que resuena en la actualidad. Dicho esto, el artículo propone desentrañar, desde una lectura crítica deleuzeana, un modo de normatividad política de los derechos que señala la relevancia de la jurisprudencia como variación, dando cuenta de la interacción deformante de la experiencia social respecto al derecho y, a su vez, de posibles nuevas dimensiones de la institución.
PERANCANGAN APLIKASI REPOSITORY JURNAL ONLINE Studi Kasus Mahasiswa Kwik Kian Gie Berbasis Android
Authors: Birowo Sigit , Budi Wasito
Published: January 2024

The system design is an important aspect in the development of information systems. The purpose of this research is to design and implement a system that will be created. And will help final year students who are looking to implement the final project can use this study as an efficient way to see the references required. This study uses the waterfall as a method to design the system. The new application is expected to handle the problems faced by students in finding reference journals. The results from this study is the online journal of information system applications that can provide ease in finding the journal. The conclusion of this study is a new information system that provide ease in searching and input journal in mobile and online within Kwik Kian Gie Campus.Keywords: internet, android, online journal, smartphone , referential studies
UNICORN OLMA YOLUNDA GİRİŞİMCİLER: DİJİTAL SAĞLIK TEKNOLOJİLERİ
Authors: KORKMAZ H. Ufuk
Published: January 2024

Teknoloji uzun yıllardır hayatımızın her alanında yoğun olarak yer almaktadır. Özellikle 2000’li yıllardan sonra sağlık alanında teknolojinin kullanımı ile dijital tedavi kavramı gelişmeye başlamıştır. Giyilebilir cihazlar ve akıllı telefonlar gibi dijital cihazların kullanılmaya başlanması ve mobil uygulamalar ve sanal gerçeklik gibi çeşitli teknolojiler ile verilerin toplanarak gerçek zamanlı olarak analiz edilmesi sağlık teknolojilerinin dijitalleşmesine katkı sağlamıştır. Dijital sağlık teknolojileri hem ulusal hem de uluslararası yatırım platformlarının finansal destek sağladığı önemli alanlardan biri olarak da karşımıza çıkmaktadır. Çalışmada doküman incelemesi araştırma yaklaşımından yararlanılmış olup girişimcilik ekosisteminde yer alan uluslararası unicornlara ve Türkiye’deki bazı sağlık teknolojisi şirketlerine yer verilmiştir. Sağlık teknolojisi alanında Türkiye’de faaliyet gösteren ve unicorn olabilmek amacıyla odaklanabilecekleri iş fikri fırsat alanlarının neler olduğunun belirlenmesi araştırmanın amacını oluşturmaktadır. “Sağlık teknolojileri alanında Türkiye’den bir unicorn çıkması için fırsatlar nelerdir?” araştırma sorusu olarak belirlenmiştir. Türkiye’de sağlık teknolojileri alanında ürün ya da hizmet geliştirmek isteyen girişimciler için fırsat ve önerilere yer verilmiştir. Yenidoğan, çocuk, yetişkin ve yaşlı bireylere yönelik özel olarak sınıflandırılmış ürün ve hizmetlerin tasarlanması önerilmektedir. Girişimcilerin değerlendirebileceği fırsat alanlarında ürün ve hizmetlerin tasarlanmasının temelini; yapay zekâ, nesnelerin interneti, makine öğrenmesi, blokzincir, sanal gerçeklik, artırılmış gerçeklik, robotik vb. teknolojiler oluşturmaktadır. Bu teknolojiler ile desteklenen dijital eczane, klinik araştırma teknolojisi, gelir döngüsü yönetimi, dijital tedavi, klinik zekâ, iş akışı otomasyon ve zindelik konularına yönelik alanlarda çalışmalar yapılması önerilmektedir. Günümüzde teknolojideki hızlı değişim ve dijital sağlık hizmetleri alanındaki gelişmeler göz önüne alındığında; girişimciliği bir kariyer olarak gören, fırsatları fark edebilen, fırsatları değerlendiren ve şirketleşen birçok yeni girişimcinin ortaya çıkması, aynı zamanda halihazırda şirketleşmiş olan projelerine yatırım almış ve yeni projelerle yeni ortaklıkların önünü açma potansiyeli olan ulusal şirketlerin unicorn unvanı elde ederek uluslararası girişimcilik ekosisteminde yer alabilmesi mümkün görünmektedir.
Inclusive Education: Necessity, Prospective Trend
Authors: Jahangir Abdullayev , Shonazar Botirov
Published: January 2024

This article describes the introduction of inclusive education, what it is, about children with disabilities, as well as the positive and negative aspects of inclusive education. Employing a thorough research methodology that involves a systematic literature review and analysis of empirical studies, the study synthesizes existing knowledge on inclusive education. The results illuminate the positive outcomes, such as enhanced social integration and academic achievement, as well as the challenges, including potential resource constraints and the need for tailored support systems. The discussion delves into the nuanced dynamics of inclusive education, weighing its merits and demerits while addressing the broader implications for educational policies and practices. Through this comprehensive approach, the article contributes to a deeper understanding of the complex interplay between inclusive education, disability, and the broader educational landscape.
Professional Information Technology Teacher Content and Essence of Competence Development
Authors: Bahriddinovich Avloqulov Jamoliddin
Published: January 2024

This study investigates the role of technological education in cultivating students' knowledge, skills, and personal qualities for future professions. Emphasis is placed on teachers' crucial role in imparting information acquisition competence to align educational content with evolving societal demands. The research methodology involves analyzing current technology education practices in general secondary schools. Results underscore the challenges faced and motivations for technology education reform. Additionally, the study reveals key elements essential for the professional growth of technology education teachers. Overall, the findings highlight the critical role of these educators in shaping an informed and skilled workforce for the demands of the modern era.
ADVANCEMENTS IN HEALTHCARE THROUGH DESIGN AND DEVELOPMENT OF AN INTELLIGENT INTRAVENOUS BAG MONITORING AND ALERT SYSTEM
Authors:   Department of Electrical Engineering, Politeknik Sultan Mizan Zainal Abidin, 23000 Dungun, Terengganu, Bin Ab Ghani Mohd Khairul Akli , Abdul Rahim Mohd Zain Bin ,   Department of Electrical Engineering, Politeknik Sultan Mizan Zainal Abidin, 23000 Dungun, Terengganu, Bin Mohd Khairul Azli Muhammad Hanis ,   Department of Electrical Engineering, Politeknik Sultan Mizan Zainal Abidin, 23000 Dungun, Terengganu
Published: January 2024

The Intelligent Intravenous Bag Monitoring and Alert System is a device designed for nighttime patient monitoring, allowing nurses to focus on other duties and prevent air bubbles from entering the patient's bloodstream. The device uses an S-type load cell to measure IV bag contents, and the Blynk app to display readings on a smartphone. The device's CPU, a NodeMCU, operates on a voltage range of 5V to 12V. The device's goal is to monitor the current IV content level, which can be checked using a smartphone and the LCD display. This innovative solution is particularly useful for intravenous (IV) treatment, which allows patients to receive fluids, medications, and nutrients directly into their veins. The device's effectiveness is further enhanced by the Blynk app.