bluuebunny/crossref_metadata_2025 huggingface dataset:
Evolving Role of Risk Tailored Therapy in Early Stage HER2-Positive Breast Cancer: A Canadian Perspective
Authors: McGee Sharon F. , Clemons Mark , Savard Marie-France
Published: June 2022

The advent of HER2-targeted therapies has led to an important shift in the management of HER2-positive early breast cancer. However, initial treatment approaches apply uniform treatment regimens to all patients, with significant treatment-related and financial toxicities for both the patient and the health care system. Recent data demonstrates that for many patients, the chemotherapy backbone, duration and nature (mono- versus dual-targeted therapy) of the HER2 blockade can be better targeted to an individual patient’s risk of recurrence. We will provide a review of current data supporting risk tailored therapy in early stage HER2-positive breast cancer along with key completed and ongoing Canadian and international risk tailored trials. Neoadjuvant systemic therapy should now be considered for patients with clinical stage 2 disease, with greater use of non-anthracycline based chemotherapy regimens. Patients with residual disease following neoadjuvant therapy should be considered for escalated treatment with adjuvant T-DM1. Patients with stage I disease can often be managed with upfront surgery and evidence-based de-escalated adjuvant chemotherapy regimens. The modest benefit of 12- versus 6 months of adjuvant HER2 therapy and/or dual adjuvant HER2 therapy should be carefully weighed against the toxicities. All patients with HER2-positive breast cancer should be enrolled in ongoing risk tailored treatment trials whenever possible. Increasing data supports risk tailored therapy in early stage HER2-positive breast cancer in place of the routine application of aggressive and toxic systemic therapy regimens to all patients. While much progress has been made towards treatment de-escalation in appropriate patients, more is needed, as we highlight in this review. Indeed, Canadian-led clinical trials are helping to lead these efforts.
Statistical Dataset and Data Acquisition System for Monitoring the Voltage and Frequency of the Electrical Network in an Environment Based on Python and Grafana
Authors: Fernández-Morales Javier , González-de-la Rosa Juan-José González-de-la , Sierra-Fernández José-María , Espinosa-Gavira Manuel-Jesús , Florencias-Oliveros Olivia , Agüera-Pérez Agustín , Palomares-Salas José-Carlos , Remigio-Carmona Paula
Published: June 2022

This article presents a unique dataset, from a public building, of voltage data, acquired using a hybrid measurement solution that combines PythonTM for acquisition and GrafanaTM for results representation. This study aims to benefit communities, by demonstrating how to achieve more efficient energy management. The study outlines how to obtain a more realistic vision of the quality of the supply, that is oriented to the monitoring of the state of the network; this should allow for better understanding, which should in turn enable the optimization of the operation and maintenance of power systems. Our work focused on frequency and higher order statistical estimators which, combined with exploratory data analysis techniques, improved the characterization of the shape of the stress signal. These techniques and data, together with the acquisition and monitoring system, present a unique combination of low-cost measurement solutions, which have the underlying benefit of contributing to industrial benchmarking. Our study proposes an effective and versatile system, which can do acquisition, statistical analysis, database management and results representation in less than a second. The system offers a wide variety of graphs to present the results of the analysis, so that the user can observe them and identify, with relative ease, any anomalies in the supply which could damage the sensitive equipment of the correspondent installation. It is a system, therefore, that not only provides information about the power quality, but also significantly contributes to the safety and maintenance of the installation. This system can be practically realized, subject to the availability of internet access.
Hepcidin as a Sensitive and Treatment-Responsive Acute-Phase Marker in Patients with Bacteremia: A Pilot Study
Authors: Koukoulas Kreon , Lygoura Vasiliki , Kartalidis Philip , Gatselis Nikolaos K. , Petinaki Efthymia , Dalekos George N. , Simos George
Published: June 2022

Hepcidin regulates iron metabolism by inhibiting intestinal iron absorption and iron release from iron stores. In addition to iron overload, inflammatory conditions also up-regulate hepcidin synthesis, which may serve as an antimicrobial defense by reducing iron availability to the invading microbes. The purpose of this study is to test this hypothesis in human patients by determining serum hepcidin concentration by enzyme linked immunosorbent assay (ELISA) in healthy blood donors (n = 60) and patients hospitalized because of bacteremia (n = 50), before (day 0) and after seven days (day 7) of appropriate antibiotic treatment. Serum hepcidin was significantly increased in patients with bacteremia, both at day 0 and at day 7, compared to healthy controls. However, there was significant reduction of serum hepcidin after 7-day treatment, in concert with changes in serum C-reactive protein (CRP). The hepcidin changes were similar for both Gram-negative and Gram-positive single infection cases, while CRP was significantly reduced only in the former. In contrast to hepcidin, the levels of serum ferritin in the patients remained high after treatment, irrespective of infection type. These data confirm the stimulation of hepcidin secretion in human subjects upon different types of systemic microbial infection and suggest that hepcidin is a more sensitive and treatment-responsive acute-phase marker than ferritin in bacteremia, which needs to be explored with bigger-sized and better-matched patient cohorts.
Τhe Study of Square Periodic Perturbations as an Immunotherapy Process on a Tumor Growth Chaotic Model
Authors: Sourailidis Dionysios , Volos Christos , Moysis Lazaros , Meletlidou Efthymia , Stouboulos Ioannis
Published: June 2022

In the present study, the simulation of an immunotherapy effect for a known dynamical system, that describes the process for avascular, vascular, and metastasis tumor growth based on a chemical network model, has been presented. To this end, square signals of various amplitudes have been used, to model the effect of external therapy control, in order to affect the population of immune cells. The results of the simulations show that for certain values of the amplitude of the square signal, the populations of the proliferating tumor cells in the vascular and metastasis stages have been reduced.
Energy Consumption Estimation for Electric Buses Based on a Physical and Data-Driven Fusion Model
Authors: Li Xiaoyu , Wang Tengyuan , Li Jiaxu , Tian Yong , Tian Jindong
Published: June 2022

The energy consumption of electric vehicles is closely related to the problems of charging station planning and vehicle route optimization. However, due to various factors, such as vehicle performance, driving habits and environmental conditions, it is difficult to estimate vehicle energy consumption accurately. In this work, a physical and data-driven fusion model was designed for electric bus energy consumption estimation. The basic energy consumption of the electric bus was modeled by a simplified physical model. The effects of rolling drag, brake consumption and air-conditioning consumption are considered in the model. Taking into account the fluctuation in energy consumption caused by multiple factors, a CatBoost decision tree model was constructed. Finally, a fusion model was built. Based on the analysis of electric bus data on the big data platform, the performance of the energy consumption model was verified. The results show that the model has high accuracy with an average relative error of 6.1%. The fusion model provides a powerful tool for the optimization of the energy consumption of electric buses, vehicle scheduling and the rational layout of charging facilities.
Situational Awareness for Smart Distribution Systems
Authors: Ge Leijiao , Yan Jun , Sun Yonghui , Wang Zhongguan
Published: June 2022

In recent years, the accelerating climate change and intensifying natural disasters have called for more renewable, resilient, and reliable energy from more distributed sources to more diversified consumers, resulting in a pressing need for advanced situational awareness of modern smart distribution systems [...]
An Assessment Method for the Impact of Electric Vehicle Participation in V2G on the Voltage Quality of the Distribution Network
Authors: Chen Wei , Zheng Lei , Li Hengjie , Pei Xiping
Published: June 2022

In order to further evaluate the impact of vehicle-to-grid (V2G) on the distribution network, this paper studies a method to assess the influence of electric vehicles participating in charge and discharge on the voltage quality of the distribution network. First, considering the state of charge of the EV, the participation of the owner and other factors, the charging and discharging model is built. Then, the probabilistic power flow calculation based on Latin hypercube sampling is used to obtain the probability distribution of the voltage amplitude of the charge and discharge load connected to the distribution network, and finally the evaluation index is established to quantify and calculate the voltage quality of the distribution network participating in the V2G process of electric vehicles. Simulation results show that the evaluation method has the advantage of fast calculation speed while ensuring known accuracy, introduces the probability distribution of expected value and variance quantification of voltage amplitude, more intuitively understands the degree of influence on voltage quality before and after V2G, and can effectively assess the impact of electric vehicles accessing the distribution network in V2G mode on the power quality of low-voltage residential areas and industrial and commercial areas, and this evaluation method can provide useful reference for the formulation of future V2G control strategies and the planning of future urban power grids.
Neutrosophic Double Controlled Metric Spaces and Related Results with Application
Authors: Uddin Fahim , Ishtiaq Umar , Hussain Aftab , Javed Khalil , Al Sulami Hamed , Ahmed Khalil
Published: June 2022

In this paper, the authors introduce the notion of neutrosophic double controlled metric spaces as a generalization of neutrosophic metric spaces. For this purpose, two non-comparable functions, ξ and Γ, are used in triangle inequalities. The authors prove several interesting results for contraction mappings with non-trivial examples. At the end of the paper, the authors prove the existence, and the uniqueness, of the integral equation to support the main result.
“Peculiar” Snoring in a 40-Year-Old Patient: A Case Report and Review of Literature
Authors: Economou Nicholas-Tiberio , Cholidou Kyriaki , Kallianos Anastasios , Weiss Katja , Knechtle Beat , Nikolaidis Pantelis T. , Trakada Georgia
Published: June 2022

This is a case description of a patient with previously diagnosed rapid eye movement sleep behavior disorder (RBD) and nocturnal enuresis, who complained about a “peculiar sound” while sleeping and, occasionally, while awake during intensive exercise, for the last three months. A home audio recording, which his wife obtained while he was sleeping, showed a high-pitched sound identified as stridor. Full video polysomnography revealed no apneas or hypopneas. The flow-volume loop yielded an inspiratory plateau, indicating variable extrathoracic obstruction. The upper and lower respiratory system computed tomography did not show any anomalies or mechanical lesions (e.g., masses and scars). Fiberoptic laryngoscopy revealed an abnormal activity of the vocal cord abductor during quiet breathing and inspiration in a supine position, leading to partial obstruction. A positive dopamine transporter scan and the coexistence of stridor, RBD, and nocturnal enuresis were diagnostic for multiple system atrophy. The patient was treated with continuous positive airway pressure as a symptomatic therapy for stridor and levodopa.
WHODAS Assessment Feasibility and Mental Health Impact on Functional Disability in Systemic Lupus Erythematosus
Authors: Duca Liliana , Roman Nadinne Alexandra , Miron Aliana , Teodorescu Andreea , Dima Lorena , Ifteni Petru
Published: June 2022

Systemic lupus erythematosus (SLE), besides rheumatological dysfunction, manifests in neuropsychiatric disorders like depression and anxiety. Mental health illnesses in SLE patients have a high prevalence and a profound impact on quality of life, generating an increased disability and premature mortality. This study aimed to establish the degree of disability in patients with SLE and the impact of depression and anxiety on patients’ functioning. Additionally, the study aimed to verify whether World Health Organization-Disability Assessment Schedule (WHODAS) 2.0 is suitable for the evaluation of patients with SLE associating depression and/or anxiety symptoms. Cross-sectional research was performed, including adult patients, diagnosed with SLE. To evaluate depression, anxiety, and functioning, approved questionnaires Hamilton Anxiety Rating Scale, Hamilton Depression Rating Scale, and, World Health Organization-Disability Assessment Schedule (WHODAS) were applied. Confirmatory factor analysis was performed on WHODAS subscales. Sixty-two patients were included in the research, with a mean of SLE diagnosis of 12.48 years; 53 patients (85%) had depression (p < 0.001). Anxiety was found in 38 patients (61.29%, p < 0.05). WHODAS assessment results depicted that 39 patients (62.90%, p < 0.05) manifested disability, from which 26 (66.66%, p < 0.05) presented moderate and severe disability. A strong correlation between the severity of anxiety and the degree of disability (r > 0.6, p < 0.001) was found. The WHODAS scale assessment proved to be a valuable tool for SLE patient’s functioning assessment. This study suggests that depression and anxiety negatively impact WHODAS disability scores, decreasing the quality of life in SLE patients.
Association between Obesity and Anemia in a Nationally Representative Sample of South Korean Adolescents: A Cross-Sectional Study
Authors: Jeong Jaehoon , Cho Younghoon , Cho In-Young , Ahn Joonho
Published: June 2022

Anemia is associated with physical, cognitive, and developmental problems. Given that there are limited studies on anemia prevalence among obese Asian adolescents and that past evidence is controversial, this study investigated the relationship between obesity and anemia in a nationally representative sample of South Korean adolescents. Data were obtained from the 2007–2019 Korea National Health and Nutrition Examination Survey. Overall, 10,231 subjects were included in the analysis. Multiple logistic regression was performed to determine the relationship between obesity and anemia. Compared with the non-obesity group, the adjusted odds ratio (OR; 95% confidence interval [CI]) of anemia was 1.00 (0.66–1.50) in the obesity group. However, in the early adolescent subgroup of 10–13 years (adjusted OR, 2.88; 95% CI, 1.20–6.95), the risk of anemia was significantly higher in the obese group than in the non-obese group. Obesity was associated with an increased risk of anemia in early adolescents. Obese adolescents aged 10–13 require special care, especially through regular examination and management for anemia.
Advanced Nanostructured MXene-Based Materials for High Energy Density Lithium–Sulfur Batteries
Authors: Tian Jingkun , Ji Guangmin , Han Xue , Xing Fei , Gao Qiqian
Published: June 2022

Lithium–sulfur batteries (LSBs) are one of the most promising candidates for next-generation high-energy-density energy storage systems, but their commercialization is hindered by the poor cycling stability due to the insulativity of sulfur and the reaction end products, and the migration of lithium polysulfide. MXenes are a type of emerging two-dimensional material and have shown excellent electrochemical properties in LSBs due to their high conductivity and large specific surface area. Herein, several synthetic strategies developed for MXenes since their discovery are summarized alongside discussion of the excellent properties of MXenes for LSBs. Recent advances in MXene-based materials as cathodes for LSBs as well as interlayers are also reviewed. Finally, the future development strategy and prospect of MXene-based materials in high-energy-density LSBs are put forward.
A Review on the Role of Bicarbonate and Proton Transporters during Sperm Capacitation in Mammals
Authors: Delgado-Bermúdez Ariadna , Yeste Marc , Bonet Sergi , Pinart Elisabeth
Published: June 2022

Alkalinization of sperm cytosol is essential for plasma membrane hyperpolarization, hyperactivation of motility, and acrosomal exocytosis during sperm capacitation in mammals. The plasma membrane of sperm cells contains different ion channels implicated in the increase of internal pH (pHi) by favoring either bicarbonate entrance or proton efflux. Bicarbonate transporters belong to the solute carrier families 4 (SLC4) and 26 (SLC26) and are currently grouped into Na+/HCO3− transporters and Cl−/HCO3− exchangers. Na+/HCO3− transporters are reported to be essential for the initial and fast entrance of HCO3− that triggers sperm capacitation, whereas Cl−/HCO3− exchangers are responsible for the sustained HCO3− entrance which orchestrates the sequence of changes associated with sperm capacitation. Proton efflux is required for the fast alkalinization of capacitated sperm cells and the activation of pH-dependent proteins; according to the species, this transport can be mediated by Na+/H+ exchangers (NHE) belonging to the SLC9 family and/or voltage-gated proton channels (HVCN1). Herein, we discuss the involvement of each of these channels in sperm capacitation and the acrosome reaction.
Hyperelastic Properties of Bamboo Cellulosic Fibre–Reinforced Silicone Rubber Biocomposites via Compression Test
Authors: Bahrain Siti Humairah Kamarul , Rahim Nor Nabilah Che Abd , Mahmud Jamaluddin , Mohammed M. N. , Sapuan S. M. , Ilyas R. A. , Alkhatib Samah Elsayed , Asyraf M. R. M.
Published: June 2022

Materials that exhibit highly nonlinear behaviour are intricate to study. This is due to their physical properties, as they possess a very large deformation. Silicone rubber is among the materials that can be classified as possessing such characteristics, despite their being soft and frequently applied in medical applications. Due to their low mechanical properties, however, it is believed that a filler addition could enhance them. This study, therefore, aims to investigate the effect of the addition of bamboo cellulosic filler to silicone rubber in terms of its compressive properties in order to quantify its material constants using the hyperelastic theory, specifically the Neo-Hookean and Mooney–Rivlin models. The specimens’ compressive properties were also compared between specimens immersed in seawater and those not immersed in seawater. The findings showed that the compressive properties, stiffness, and compressive strength of the bamboo cellulosic fibre reinforced the silicone rubber biocomposites, improved with higher bamboo filler addition. Specimens immersed in seawater showed that they can withstand a compressive load of up to 83.16 kPa in comparison to specimens not immersed in seawater (up to 79.8 kPa). Using the hyperelastic constitutive models, the Mooney–Rivlin model displayed the most accurate performance curve fit with the experimental compression data with an R2 of up to 0.9999. The material constant values also revealed that the specimens immersed in seawater improved in stiffness property, as the C1 material constant values are higher than for the specimens not immersed in seawater. From these findings, this study has shown that bamboo cellulosic filler added into silicone rubber enhances the material’s compressive properties and that the rubber further improves with immersion in seawater. Thus, these findings contribute significantly towards knowledge of bamboo cellulosic fibre–reinforced silicone rubber biocomposite materials.
A Single-Component Blue Light-Induced System Based on EL222 in Yarrowia lipolytica
Authors: Wang Zhiqian , Yan Yunjun , Zhang Houjin
Published: June 2022

Optogenetics has the advantages of a fast response time, reversibility, and high spatial and temporal resolution, which make it desirable in the metabolic engineering of chassis cells. In this study, a light-induced expression system of Yarrowia lipolytica was constructed, which successfully achieved the synthesis and functional verification of Bleomycin resistance protein (BleoR). The core of the blue light-induced system, the light-responsive element (TF), is constructed based on the blue photosensitive protein EL222 and the transcription activator VP16. The results show that the light-induced sensor based on TF, upstream activation sequence (C120)5, and minimal promoter CYC102 can respond to blue light and initiate the expression of GFPMut3 report gene. With four copies of the responsive promoter and reporter gene assembled, they can produce a 128.5-fold higher fluorescent signal than that under dark conditions after 8 h of induction. The effects of light dose and periodicity on this system were investigated, which proved that the system has good spatial and temporal controllability. On this basis, the light-controlled system was used for the synthesis of BleoR to realize the expression and verification of functional protein. These results demonstrated that this system has the potential for the transcriptional regulation of target genes, construction of large-scale synthetic networks, and overproduction of the desired product.
Thermal Conductivity of Yttria-Gadolinia Solid Solution Optical Ceramics in the Temperature Range 50–300 K
Authors: Balabanov Stanislav , Evstropov Timofey , Permin Dmitry , Postnikova Olga , Praded Alexander , Popov Pavel
Published: June 2022

This study looked at the thermal conductivity of translucent (Y1−xGdx)2O3 (where 0 ≤ x ≤ 1) solid solution ceramics in the temperature range from 50 K to 300 K. The samples were obtained by hot pressing from high-purity nanopowders at 1600 °C, no sintering additives were used. Compositions with cubic syngony (x ≤ 0.7) and a monoclinic one (x ≥ 0.9) were investigated. Furthermore, a dense sample of cubic Gd2O3 with a LiF sintering additive was obtained and its thermal conductivity was determined (k = 11.7 W/(m K) at 300 K). It was shown that in the range of solid solution ceramic compositions 0.2 ≤ x ≤ 0.7, the thermal conductivity was practically unchanged and close to the value k ≈ 5 W/(m K) at 300 K.
Vegetation Disturbance and Recovery Dynamics of Different Surface Mining Sites via the LandTrendr Algorithm: Case Study in Inner Mongolia, China
Authors: Liu Yunxuan , Xie Miaomiao , Liu Jinying , Wang Huihui , Chen Bin
Published: June 2022

Mining sites are areas where mining and restoration coexist and are constantly changing. The vegetation condition can reflect the process of surface mining and restoration, while quantifying the impacts of different mining patterns and surrounding environments on vegetation is the key to balancing mining activities and ecological restoration. In this study, long-term monitoring from 1986 to 2020 was implemented by the LandTrendr algorithm to reveal the ecological impacts of two concentrated and contiguous surface mining sites with different mining patterns (scattered and aggregated mining) and surrounding environments in Inner Mongolia, China. The results show that it is reasonable to use the LandTrendr algorithm for long-term monitoring of surface mining sites, and that the ecological impacts of different surface mining sites in ecologically fragile areas have the same regularity. As the duration increases, the magnitude of disturbance decreases, and the magnitude of recovery first decreases and then reaches a natural fluctuation state after 20 years of recovery. Different mining patterns and surrounding environments bring different ecological impacts. Scattered mining areas are more likely to produce natural recovery while the restored ecosystem is more stable. The performance of mining development disturbance is more obvious in places with better ecological environment, while the effect of ecological restoration is also more significant. This study can provide guidance for the rational planning of mining and restoration activities in ecologically fragile areas.
Experimental Investigation of Two Switching States of an Active Foil Bearing during Start-Up
Authors: Schmiedeke Hannes , Sick Jan-Hinrich , Sinapius Michael
Published: June 2022

The next few years will be marked by major changes in the mobility sector in order to come closer to CO2 neutrality. Especially in the commercial vehicle sector, fuel cells can make an important contribution. In order to achieve this, the efficiency of all subcomponents of a vehicle has to be improved. This also includes the bearings in the electrical air compressors. The frequent start–stop cycles are critical, as they can lead to higher wear and thus a shorter service life. One solution is a prototype that can actively switch between a triangular profile and a round bearing shape. In this work, the two switching states are investigated experimentally. Instead of the thin bearing sleeve of the prototype, rigid sleeves are used for each switching shape. This allows the shape itself to be studied without the contribution of the stiffness of the thin bearing sleeve along with the actuators. The examination includes static load tests and run-out tests in the range of the lift-off speed. Alongside this, the difficulties of the bearing production and the improvement of the test rig used are pointed out.
Multiwalled Carbon Nanotube-Coated Poly-Methyl Methacrylate Dispersed Thermoplastic Polyurethane Composites for Pressure-Sensitive Applications
Authors: Muhammad Imran Syed , Go Gwang-Myeong , Hussain Manwar , Al-Harthi Mamdouh A.
Published: June 2022

Thermoplastic polyurethane (TPU) is a widely used polymer for a variety of pressure sensing applications because of its softness and shape memory. This work reports the synthesis of novel TPU-based three-dimensional structured (3D) pressure-sensitive composites via the melt mixing method. Poly-methyl methacrylate (PMMA) microbeads of different sizes (5, 10, and 20 µm) were first coated with multi-walled carbon nanotubes (MWCNT) and then incorporated into the TPU matrix for achieving an early electro conductive percolation threshold compared to without PMMA beads. The addition of MWCNT coated PMMA beads reduced the TPU insulated areas by creating a 3D conductive network that finally reflected the early percolation threshold during external pressure. Raman microscopy and XRD results confirmed the MWCNT coated nicely on the surface of PMMA beads. The pressure sensitivity results also confirmed the decrease in resistance of the composites with the increase in the applied external pressure. Composites with 10 µm PMMA bead size showed the most linear responses to the decrease in resistance with increasing pressure and showed a higher strain gauge factor value (3.15) as compared to other composites, which had values of 2.78 and 2.42 for 20 and 5 µm, respectively. Microstructure analysis of the composites by SEM, capacitance, permeability, and thermal conductivity measurements was also investigated to support the above evidence. The results support the suitability of this novel composite as a potential candidate for pressure sensing applications.
The Effect of COVID-19 on Hemoglobinopathy Patients’ Daily Lives While Quarantined: Four Greek Hospitals’ Experiences
Authors: Delicou Sophia , Xydaki Aikaterini , Manganas Konstantinos , Koullias Emmanouil , Evliati Loukia , Kalkana Chryssoula , Diamantidis Michael D. , Manafas Achilles , Katsatou Marianna , Roumpatis Leonidas , Aforozis Theodoros
Published: June 2022

During a pandemic, people are fearful of becoming infected with the virus, which causes anxiety, loss of purpose, and depression. This study aimed to evaluate the social and psychological impact, as well as the impact on homecare, of patients with hemoglobinopathies during the pandemic. Material and Methods: In total, 130 patients from four Thalassemia and Sickle Cell Disease Units of the National Health System of Greece Hospitals were examined via an anonymous questionnaire developed and distributed through stratified sampling. Results: Transfusion-dependent thalassemia, transfused sickle cell disease, and other hemoglobinopathies were represented by 130 patients. During the pandemic, the main concern of patients was the affordability of blood for transfusion. During the lockdown, patients’ moods varied, and their daily lives were disrupted by a lack of access to basic goods and communication with friends and family. Their eating habits, access to exercise, and, to a lesser extent, their financial situation have all been affected in their daily lives. It is crucial to highlight that while access to health services did not suffer in terms of medication and regular visits for their actual disease, it did suffer in terms of the systematic monitoring of complications.
Dukungan Organisasi, Keadilan Organisasi dan Komitmen Organisasi Terhadap Kinerja Karyawan Pada PT. Batanghari Barisan Padang
Authors: Karlinda Ai Elis , Nadilla Nia , Sopali Mardhatilla Fitri
Published: June 2022

Human resources are important for the company because they have a role as a potential driver of all company activities. Companies that have quality human resources can easily achieve the performance that has been set. Performance measurement is a very important thing as a whole in an organization. Every company will always try to improve employee performance for the company's success. Several factors that can affect employee performance include: organizational support, organizational justice, and organizational commitment. This study is intended to determine how much influence organizational support, organizational justice and organizational commitment have on employee performance at PT. Batanghari Barisan Padang. Methods of collecting data through surveys and distributing questionnaires, with a sample of 72 respondents PT. Batanghari Baris. The analytical method used is multiple linear regression using SPSS 22. The results obtained are Organizational Support partially has a positive and significant effect on employee performance where H0 is rejected and Ha is accepted, Organizational Justice partially has a positive and significant effect on Employee Performance where H0 is rejected and Ha is accepted, and organizational commitment has a positive and significant effect on employee performance where H0 is rejected and Ha is accepted. Organizational support, organizational justice and organizational commitment together have a positive and significant effect on employee performance. The value of the contribution of variables that affect organizational support, organizational justice, and organizational commitment is 70.2%. So this research is very appropriate and becomes a reference in improving employee performance in advancing the company.
El “sol del 24 de marzo”, un nuevo amanecer para la República
Authors: Fabris Mariano
Published: June 2022

Este artículo se presenta como un aporte a la reconstrucción de la trama de apoyos civiles que convocó el golpe de Estado del 24 de marzo de 1976. Analiza, en concreto, al grupo de dirigentes, académicos y periodistas que poco después del golpe comenzó a editar la revista Rumbo Social y que, desde sus páginas, no sólo dio la bienvenida al nuevo gobierno, sino que vislumbró en la coyuntura de 1976 la oportunidad para poner en marcha una transformación radical de la sociedad argentina. El abordaje pondera sus trayectorias en espacios de sociabilidad católica, identifica el lugar que le otorgaron a los valores religiosos y a la jerarquía eclesiástica en la nueva coyuntura y analiza sus representaciones sobre el golpe, la democracia y la sociedad a la luz de una identidad fuertemente antiperonista.
La historiografía argentina reciente: recorridos, logros y desafíos
Authors: Lobato Mirta Zaida , Solís Carnicer María del Mar , Wasserman Fabio
Published: June 2022

El texto presenta los trabajos que integran el dossier sobre el estado de la historiografía argentina, los cuales fueron elaborados a partir de las exposiciones realizadas en abril y mayo de 2021 en las Jornadas que conmemoraron los diez años de la Asociación Argentina de Investigadores en Historia (AsAIH). Para ello, se traza un breve panorama de la historiografía argentina desde la recuperación de la democracia en 1983, teniendo en cuenta tanto el contexto académico e institucional como el político, social y económico; repasa los principales hitos en la trayectoria de la AsAIH; destaca algunas innovaciones historiográficas producidas en las últimas décadas; y por último presenta una breve síntesis de los textos que forman parte del dossier.
La Federación Gimnástica Española y el “problema de la educación física” en la España de principios del siglo XX
Authors: Torrebadella-Flix Xavier
Published: June 2022

En el proceso de institucionalización de la educación física en España, la constitución de la Federación Gimnástica Española surgida en 1898 trató de fomentar la creación y unión federada de un asociacionismo gimnástico-deportivo. No obstante, esta institución sufrió las fragilidades políticas y culturales de una sociedad que todavía no había alcanzado un grado de cultura democrática. La falta de apoyo político y la inclinación a un nacionalismo castellano fueron parte del fracaso de esta federación, pero también, con él, fracasaba el proyecto político educativo de plantear una verdadera apuesta por la educación física del país.
El testimonio como “supervivencia” de un pasado “irrevocable”: historiografía, presente y temporalidad
Authors: Urteneche Gonzalo
Published: June 2022

Tradicionalmente, el testimonio fue entendido por la historiografía o bien como un vestigio del pasado, del que podía extraerse conocimiento por medios inferenciales o bien como una vía de acceso directo al mismo, en general marcado por la noción psicoanalítica de “trauma”. En este trabajo propongo una aproximación al testimonio como “supervivencia” de un “pasado irrevocable”. A través del concepto de “supervivencia”, tomado del historiador del arte Georges Didi-Huberman, intentaré desanclar al testimonio de sus usos marcados por la dicotomía temporal antes mencionada y valorar su carácter temporalmente impuro. La noción de “pasado irrevocable” me permitirá proponer que el tiempo histórico, en general, y el presente, en particular, no son algo dado y autoevidente sino construido y disputado.
Os estudos culturais na perspectiva pós-colonialista e interculturalista
Authors: MERÇON Aline , Dos SANTOS Kleber José
Published: June 2022

Nas últimas décadas os Estudos Culturais (EC) transformaram-se, na sua forma interdisciplinar, em um fenômeno de repercussão internacional, consolidando-se como um importante campo teórico e de investigação. O presente artigo reveste-se de um interesse sobretudo didático, podendo ser aplicado como leitura de enquadramento e introdução aos Estudos Culturais. Como objetivo principal pretende dar uma visão sucinta e clara, desde o contexto histórico e social de origem até os temas e tópicos de que se tem ocupado nos tempos atuais, procurando desenhar o seu estatuto disciplinar e acadêmico. Na primeira parte do texto apresenta-se os seus antecedentes, na segunda, terceira e quarta parte, uma incursão breve e delineada dos contornos e desdobramentos que este campo de estudos vem assumindo na contemporaneidade.
Brega, brega pop e tecnobrega
Authors: SOUSA Cerqueira Reginaldo
Published: June 2022

A cultura musical da Amazônia, em particular a do estado do Pará, é composta por uma variedade de ritmos, estilos e sonoridades. Essa pluralidade musical dialoga e se mescla a elementos da cultura cabocla e urbana, e é ressignificada como elemento de identidade pelas populações da periferia das cidades amazônicas. Um estilo musical que, no Pará, adquiriu um significado diferente daquele comum ao restante do Brasil é o brega. Este artigo analisa as transformações do brega paraense e os sentidos que adquiriu ao longo das décadas de 1980, 1990 e 2000. O objetivo é perceber, a partir do conceito de performatividade de gênero, como as pessoas que vivem e consomem as canções bregas criam modos de ser que subvertem as normas sociais que se fundamenta em na concepção de masculino e feminino.
Relações entre Maçonaria e Igreja Católica no sul de Mato Grosso
Authors: DE JESUS Pereira Rafael , SENA Divino Marcos
Published: June 2022

Neste artigo analisamos a relação entre Maçonaria e Igreja Católica em Corumbá, Sul de Mato Grosso, fronteira Brasil-Bolívia, no final do século XIX. Essa relação se constituiu de diferentes maneiras, intercalando períodos de maior proximidade com outros de embates intensos. As fontes de imprensa, breves históricos das lojas maçônicas existentes na região (Caridade e Silêncio e Pharol do Norte) fornecidos pelas instituições e por antigos membros, entre outras, embasaram a construção deste estudo.
Reflexões sobre o ensino de História local
Authors: Pontes de LIMA Ana Cláudia , Nascimento OLIVEIRA Ana Lúcia
Published: June 2022

Este artigo é parte de uma dissertação de mestrado sobre o ensino de história local.  Tem como objetivo investigar a aprendizagem histórica a partir da análise dos relatos  de professores e estudantes da Escola Municipal Instituto Presbiteriano de Heliópolis, Garanhuns –Pernambuco , na vivência do projeto pedagógico “Memórias de Garanhuns”.
Olivares e a universidade de Salamanca
Authors: CARVALHO Guilherme
Published: June 2022

Neste artigo, analisamos uma dedicatória a Gaspar de Guzmán, O Conde-duque de Olivares, contida em uma relação fúnebre acerca das pompas que a Universidade de Salamanca ofereceu em virtude da morte do Rei Filipe III de Espanha, em 1621. Tal obra foi escrita por Angel Manrique, catedrático da Universidade de Salamanca. A partir dessa dedicatória, propomos uma interpretação histórica com enfoque nas estratégias retóricas utilizadas por Manrique para angariar as boas graças de Guzmán em favor da universidade, a partir de uma lógica corporativa que propõe uma relação do tipo clientelar entre a universidade e o valido de Filipe IV.
Surface Wettability and Colour Change of Betung Bamboo Strands Treated with 1% NaOH under Various Immersing Times
Authors: Murda Rio Ardiansyah , Maulana Sena , Mangurai Silvia Uthari Nuzaverra Mayang , Julyatmojo Fajar Aditya , Suwanda Astri Aulia , Fadlan Muhammad Saeful
Published: June 2022

Bamboo was a material with enormous potential to be used as raw material for various purposes. This material has good properties for structural purposes such as buildings and furniture or converted to a composite product such as bamboo oriented strand board (BOSB). This study was aimed to determine the wettability properties and the colour change of Dendrocalamus asper bamboo strands after alkali immersing treatment with 1% NaOH solution. The treatments were carried out for 1, 2, and 3 hours, respectively. The wettability of surfaces is quantified by computing the value of the K parameter or the contact angle change rate constant. Meanwhile, the colour change parameter of bamboo strands was quantified by portable colour difference meter CDX – 105 to determine the brightness intensity of a combination of red–green and blue-yellow. The results show that the wettability properties of bamboo strands were getting better after the treatments. On the other hand, the bamboo strands' colour was darker due to the alkali immersion treatment. The optimum duration of alkali immersing treatment with 1% NaOH was 2 hours.
Actividades extracurriculares en inglés: su impacto en la motivación y el desarrollo de prácticas situadas en estudiantes universitarios
Authors:   , Cabrera Arias Sandra Mercedes
Published: June 2022

En las universidades públicas ecuatorianas no existen programas de actividades extracurriculares de refuerzo del aprendizaje del inglés como lengua extranjera. El presente estudio tuvo como principal objetivo determinar de qué manera las actividades extracurriculares (AE) pueden influir tanto en la motivación como en el desarrollo de las prácticas del lenguaje en el proceso del aprendizaje del inglés como lengua extranjera. Para ello se empleó un diseño de investigación explicativo mixto DEXPLIS. Se intervino en dos fases con una duración de 10 semanas cada una. Participaron 50 y 49 estudiantes, respectivamente, quienes cursaban segundo (A2-) y tercer nivel (A2) de inglés en el Instituto de Lenguas de la Universidad de Cuenca. Se planificaron cuatro actividades extracurriculares: club de conversación, grupo de interacción en WhatsApp, música en inglés y cine foro. La promoción boca a boca agotó inmediatamente todos los cupos disponibles para las actividades que se presentaron. La aplicación del proyecto permitió obtener resultados de la situación inicial y final tanto de los grupos intervenidos como de los grupos no intervenidos. En términos generales, se advirtió que las AE influyeron positivamente en la primera y segunda fase pues en ambas ocasiones el promedio de rendimiento mejoró significativamente. Ello no ocurrió con el grupo de control que únicamente mejoró en la primera fase y fue superado por el grupo intervenido en la segunda fase. Pese a que no se distingue un patrón constante en el aumento del nivel de las destrezas básicas, la diferencia más marcada que se observa en el grupo intervenido es en el uso de la lengua, mismo que aumentó en 0,35 puntos en cada fase. Además, de acuerdo al estudio cualitativo, tutores y estudiantes declararon que aumentó la motivación por aprender el inglés como lengua extranjera. La motivación se ve reforzada por el desarrollo de actividades que son del gusto personal de los estudiantes en la lengua meta.
Descomposición de agua sobre películas de cobalto puras un estudio mediante espectrometría de masa de desorción térmica
Authors:   , Amorebieta Valentín Tomás
Published: June 2022

El empleo de películas metálicas evaporadas en la realización de estudios contundentes a la caracterización y al conocimiento de la interfase metal/gas y de los procesos cinéticos que en éstas tienen lugar, debe estar precedido por la acumulación de información acerca de la estructura y de las propiedades de las superficies en su estado de máxima pureza. Una vez logrado esto, recién se pueden comenzar a investigar los cambios que se producen en sus propiedades características cuando se adsorben especies gaseosas sencillas criteriosamente seleccionadas y si ocurren, las reacciones superficiales con sus probables mecanismos. Dentro de este camino, en éste laboratorio, se han realizado estudios de las propiedades eléctricas y fotoeléctricas y sus cambios por la adsorción de agua de diferentes sustratos metálicos: hierro, oro, cobre, níquel, platino y cobalto. El cobalto y sus compuestos presentan una importante acción catalizadora. Por ejemplo: un catalizador constituido principalmente por cobalto hierro se emplea en la síntesis de FISCHER-TROPSOH. Además, es ampliamente empleado en la fabricación de aleaciones resistentes a la oxidación y corrosión. El agua por su parte, es un importante agente corrosivo, encontrándose presente como impureza o producto de reacción, deseado o no, en numerosos procesos químicos. En consecuencia, su interacción con superficies de cobalto puras merece ser estudiadas. A pesar de esto, en la literatura consultada se encontró un único trabajo publicado. En lo referente a su interacción con otros gases se ha encontrado un estudio con hidrógeno y otro con monóxido de carbono. En este laboratorio BORRAJO comenzó un estudio de esta naturaleza como complemento de su trabajo sobre "Propiedades eléctricas y fotoeléctricas de películas policristalinas de cobalto". El objeto del presente trabajo es el de continuar loa estudios sobre este tema en la medida de las posibilidades experimentales disponibles. Para tal fin se combinó la espectrometría de masa de desorción térmica (E.M.D.T.) con las mediciones de la función trabajo (F.T.), de la resistencia eléctrica (R.E.), así como de sus cambios.
Nano-Green Betel Leaf Extracts (Piper betle L.) Inhibits the Growth of Streptococcus mutans and Staphylococcus aureus
Authors: Florenly Florenly , Novelya Novelya , Janiar Mizeli , Miranda Miranda , Hai Le Quang Phan Dang , Quang Phang Minh
Published: June 2022

Abstract: Streptococcus mutans is a type of bacterium that initiates plaque formation on the tooth surface causing tooth decay, meanwhile, Staphylococcus aureus causes pyogenic infections such as abscesses to necrosis. Green betel leaf (Piper betle L.) contains secondary meta-bolites that have the potential as antibacterial. This study aimed to investigate the effectiveness of green betel leaf extract (Piper betle L.) in micro and nano sizes against Streptococcus mutans and Staphylococcus aureus. This was an experimental and laboratory study with a post-test-only design. The results showed that nano-green betel leaf extracts had antibacterial activity against Streptococcus mutans and Staphylococcus aureus. Green betel leaf extract had a much larger inhibition zone against Staphylococcus aureus rather than against Streptococcus mutans in all groups (p<0.05), with inhibitory diameters of 13,883±1.1496 mm (micro 10%), 16,767± 1.8779 mm (micro 30%), and 18.667±3.148 mm (nano), respectively. A stable increase in antibacterial activity was derived from micro-green betel leaf extracts (Piper betle L.) concentrations of 10%, 30%, and nanoparticle size. In conclusion, nano-green betel leaf extract (Piper betle L.) showed better antibacterial effectiveness than micro-sizes in inhibiting Streptococcus mutans and Staphylococcus aureus bacteria.Keywords: Piper betle L.; nanoparticles; antibacterial; Streptococcus mutans; Staphylococcus aureus
Enhancement of two-dimensional electron gas mobility using strain reduced AlGaN barriers grown by metalorganic vapor phase epitaxy under nitrogen atmosphere
Authors: Yamada Atsushi , Yaita Junya , Kotani Junji
Published: June 2022

We demonstrated high-electron-mobility transistors (HEMTs) with enhanced two-dimensional electron gas (2DEG) mobility using a low-strain AlGaN barrier grown by metalorganic vapor phase epitaxy under a nitrogen atmosphere. We investigated the effects of the growth temperature under a nitrogen atmosphere on the electrical properties of AlGaN-HEMT structures, focusing on 2DEG mobility. At growth temperatures below 855 °C, the 2DEG mobility decreased with decreasing growth temperature owing to an increase in the threading dislocation density. However, at growth temperatures above 855 °C, the 2DEG mobility decreased with increasing growth temperature. This finding was attributed to the compressive strain in the GaN channel, which increased with increasing growth temperature owing to the increased tensile strain in the AlGaN barriers. We concluded that temperatures around 855 °C are suitable for AlGaN barrier growth under nitrogen atmosphere. Finally, we achieved the highest 2DEG mobility of 2182 cm2 V−1 s−1 with a low sheet resistance of 406 Ω sq−1. using an Al0.41Ga0.59N barrier.