bluuebunny/crossref_metadata_2025 huggingface dataset:
Organobase-catalyzed carboxyl-yne click polymerization
Authors: Si Han , Qin Anjun , Tang Ben Zhong
Published: February 2023

Unsaturated polyester can be directly chemically modified, which provides sufficient feasibility for further functionalization of polymeric polyester, so the simple synthesis of unsaturated polyester is of great significance. We have developed click polymerization of diynes and dicarboxylic acids with DABCO as catalyst. After the optimization of reaction conditions, the poly (carbonyl enol ester) with molecular weight of 24 200 was obtained, and the polymerization yield reached 96%. The synthesis of fat and aromatic poly (carbonyl enol ester) could be realized in different solvents. The polymerization reaction has excellent regioselectivity and stereoselectivity, and the obtained aliphatic unsaturated polycarbonyl enol esters are crystalline polymers. In addition, the polymerization reaction needs mild conditions, short reaction time, can be carried out in air atmosphere, and has low requirements on the purity and types of reaction reagents, and can realize gram-level polymer preparation, thus providing a convenient, efficient and rapid synthetic route for the preparation of enol ester materials.
FlowBO: A Flow Chemistry Bayesian Optimization Framework Benchmarked by Kinetic Models
Authors: Luo Guihua , Yang Xilin , Qi Tingting , Xu Qilin , Su Weike , Su An
Published: February 2023

The applications of flow chemistry (continuous flow reactions) in the synthesis of pharmaceuticals and fine chemicals require more advanced optimization algorithms to guide laboratory-scale and industry-scale optimization. Although several Bayesian Optimization (BO) frameworks have been developed, they are rarely equipped with state-of-the-art noise-handling acquisition functions and have not been benchmarked by multiple real-world continuous flow kinetic models. In this study, we developed FlowBO for flow chemistry, equipped with the recently-developed MOO algorithm qNEHVI that can better handle experimental noise and make parallel recommendations. Also, five kinetic models built from experimental results, including four series reactions, were used as benchmarks for FlowBO and two other recognized BO frameworks. The results show that FlowBO outperforms in all four series reaction cases with optimization results >99.9% for conversion and selectivity. At the same time, FlowBO offers a range of optimum advantages with a wide choice of temperature, residence time, and reactant concentration, facilitating process optimization for subsequent steps (i.e. separation).
A Rapid Dynamic Headspace Method for Authentication of Whiskies using Artificial Neural Networks
Authors: Swift James , Turner Matthew Arran , Reynolds James Christopher
Published: February 2023

A rapid headspace analysis method for the authenticity testing of whiskies of different brands and years was developed for a low cost, deployable atmospheric pressure ionisation mass spectrometer, which required minimal sample preparation. Principal component analysis was applied to the time-averaged mass spectra, the classification results for which were compared against artificial neural network methods. The artificial neural network was found to outperform PCA, achieving 95% accuracy for all sampling conditions, with only two misclassifications under the ideal conditions, while requiring less development time.
Structural elements that enable specificity for mutant EGFR kinase domains with next-generation small-molecule inhibitors.
Authors: Damghani Tahereh , Wittlinger Florian , Beyett Tyler S. , Eck Michael J. , Laufer Stefan A. , Heppner David E.
Published: February 2023

Specificity for a desired enzyme target is an essential property of small-molecule inhibitors. Molecules targeting oncogenic driver mutations in the epidermal growth factor receptor (EGFR) kinase domain have had a considerable clinical impact due to their selective binding to cancer-causing mutants compared to wild type. Despite the availability of clinically approved drugs for cancers driven by EGFR mutants, persistent challenges in drug resistance in the past decades have led to newer generations of drugs with divergent chemical structures. The present clinical complications are mainly due to acquired resistance to third-generation inhibitors by the acquisition of the C797S mutation. Diverse fourth-generation candidates and tool compounds with C797S selectivity have emerged and their structural characterization has allowed for understanding of the molecular factors that allow for EGFR mutant selective binding. Here, we have reviewed all known structurally-characterized EGFR TKIs targeting clinically-relevant mutations to identify consistent binding mode features that enable C797S inhibition. Newer generation EGFR inhibitors exhibit consistent and previously underutilized hydrogen bonding interactions with the conserved K745 and D855 residue side chains. We also consider binding modes and hydrogen bonding interactions of inhibitors targeting the classical ATP and the more unique allosteric sites.
Nano-impact single-entity electrochemistry enables plasmon-enhanced electrocatalysis
Authors: Ganguli Sagar , Zhao Ziwen , Parlak Onur , Hattori Yocefu , Sa Jacinto , Sekretareva Alina
Published: February 2023

Plasmon-enhanced electrocatalysis (PEEC) based on a combination of localized surface plasmon resonance excitation and electrochemical bias applied to plasmonic material can result in improved electrical-to-chemical energy conversion compared to conventional electrocatalysis. Here, we demonstrate the advantages of nano-impact single-entity electrochemistry (SEE) for investigating the intrinsic activity of plasmonic catalysts at the single-particle level using glucose electrooxidation on gold nanoparticles as a model reaction. We show that in conventional ensemble measurements, plasmonic effects have minimal impact on photocurrent because the Fermi level of the deposited gold nanoparticles continuously equilibrates with the working electrode potential, leading to fast neutralization of hot carriers by the measuring circuit. The photocurrents detected in these measurements are caused by photo-induced heating of carbon-based electrodes. In SEE, the Fermi level of diffused gold nanoparticles is unaffected by the working electrode potential. As a result, plasmonic effects are the dominant source of photocurrents in SEE.
Use of 1-Chlorovinyl p-Tolyl Sulfoxides as Alkynylmagnesium Chloride Sources
Authors: Sekiguchi Koto , Kimura Tsutomu
Published: February 2023

A method for generating alkynylmagnesium chlorides from 1-chlorovinyl p-tolyl sulfoxides and an isopropylmagnesium chloride-lithium chloride complex (turbo Grignard reagent) has been developed. The method consists of a sulfoxide/magnesium exchange reaction of 1-chlorovinyl p-tolyl sulfoxides and a turbo Grignard reagent, a FritschButtenbergWiechell rearrangement of the resulting magnesium alkylidene carbenoids, and a deprotonation of terminal alkynes with a turbo Grignard reagent. The resulting alkynylmagnesium chlorides are reacted with a variety of electrophiles to generate internal alkynes.
СТРУКТУРА БЛИЖНЕГО ОКРУЖЕНИЯ ИОНОВ В ВОДНЫХ РАСТВОРАХ НИТРАТА КАЛЬЦИЯ ПО ДАННЫМ РЕНТГЕНОСТРУКТУРНОГО АНАЛИЗА
Authors: Смирнов П.Р. , Гречин О.В.
Published: February 2023

Методом РСА определена координация ионов в водных растворах нитрата кальция в широком диапазоне концентраций. В насыщенном растворе катион координирует пять молекул воды и один нитрат-ион в монодентатном положении. С разбавлением число координируемых в первой оболочке иона Ca2+ молекул воды постепенно увеличивается до шести, а также начинают формироваться вторая координационная сфера катиона и гидратная сфера аниона. Ионные пары определяют структуру растворов во всем исследованном диапазоне концентраций.
Dizel yakıtı-bitkisel yağ-dietilen glikol dimetil eter karışım yakıtlarının bir dizel motorun performans, yanma ve emisyon karakteristiklerine etkilerinin incelenmesi
Authors: GÜLÜM Mert
Published: February 2023

Dizel yakıtı+bitkisel yağ+dietilen glikol dimetil eter karışımlarının tek silindirli bir dizel motorda tam gaz ve farklı devirlerde (1000-2200 devir/dakika) kullanılmasının performans, yanma ve emisyon karakteristiklerine etkileri incelenmiştir. Maksimum silindir sıcaklığı değerleri ile maksimum silindir sıcaklığının elde edildiği krank mili açısı değerleri interpolasyon ve ekstrapolasyon yöntemleriyle tahmin edilmiştir. Silindir sıcaklığının devir sayısı ve krank mili açısına göre değişimi için en küçük kareler regresyonu yardımıyla 3-boyutlu bir denklem elde edilmiştir. Dizel yakıtı kullanımına göre, karışım yakıtları kullanıldığında ortalama olarak tutuşma gecikmesi, maksimum silindir sıcaklığı, egzoz gazı sıcaklığı ve emisyonlar (karbonmonoksit, is ve hidrokarbon) azalmış, fakat özgül yakıt tüketimi artmıştır. Hacimsel olarak % 4 oranında dietilen glikol dimetil eter içeren karışım için efektif verim (% 1.4895), efektif güç (%2.5552), maksimum silindir basıncı (% 2.0448) ve maksimum ısı yayılımı oranı (% 7.6845) artmıştır. Elde edilen 3-boyutlu denklem yardımıyla farklı yakıtlar için hesaplanan silindir sıcaklığı değerlerinin hata oranları % 5’in altındadır.
Reaction of Carbon Dioxide Gas Absorption with Suspension of Calcium Hydroxide in Slurry Reactor
Authors: Mufrodi Zahrul , Shitophyta L. M. , Sulistyo Hary , Rochmadi . , Aziz Muhammad
Published: February 2023

Chemical phenomena involving three phases (solid, liquid, and gas) are often found in the industry. Carbonate (CaCO3) is widely used in industries as a powder-making material in the cosmetic industry, a pigment in the paint industry, and filler in the paper and rubber industry. This research aim to study the ordering process carbonate deposits (CaCO3) from the absorption process of CO2 gas with Ca(OH)2 suspension. The absorption reaction of CO2 gas with Ca(OH)2 suspension was carried out in a stirred slurry tank reactor. Initially, the reactor containing water was heated to a certain temperature, then Ca(OH)2 was added to the reactor. Furthermore, CO2 gas with a certain flow rate and temperature (according to the reactor temperature) is flown with the help of a gas distributor. Samples were taken every 1 min until the concentration of Ca(OH)2 could not be detected (completely reacted). The variables in this study were: stirrer rotation speed (5.66711.067 rps), CO2 gas flow rate (34.0127–60.5503 c/s), and temperature (30–50°C). The mass transfer coefficient and the reaction rate coefficient were determined by minimizing Sum of Squares of Errors (SSE). This experimental process follows a dynamic regime. A dimensionless number relationship for the gas-liquid mass transfer for the value range is Re1 = 18928.76-38217.20, Sh = 0.07928 Reg0.4383 Rel0.4399 Sc0.6415 with an error of 5.19%. The dimensionless number relationship for solid-liquid mass transfer is Sh = 0.0001179 Reg0.4674 Rel0.5403 Sc1.444 with an error of 7.31%. The relationship between the reaction rate constant and the temperature in the 30-50 °C range can be approximated by the Arrhenius equation, namely kr = 1771000 e-2321.4/T cm3/mgmol/s with an error of 3.63%. Doi: 10.28991/ESJ-2023-07-02-02 Full Text: PDF
Fear and Group Defense Effect of a Holling Type IV Predator-Prey System Intraspecific Competition
Authors: Pratama Rian Ade , Loupatty Martha , Hariyanto Hariyanto , Caesarendra Wahyu , Rahmaniar Wahyu
Published: February 2023

Field and experimental data on aquatic ecosystem species show the effect of fear on changing prey demographics. The fear effect has an impact on aquatic ecosystems, such as species migration to settled areas. In this paper, the type of research described is a literature study. The cost effect assigned to the reproductive system of the prey population and the predation function response are given as Holling Type IV for research purposes to model the fear effect. Some research novelties, the equilibrium points are all shown in the population dynamics system model with an analysis of positive equilibrium. Positive and biologically realistic equilibrium points were analyzed using the Routh-Hurwitz criterion which is mathematically a local asymptotically stable. A pair of imaginary eigenvalues with a negative real part can increase population growth. An equilibrium region showing equilibrium for several parameters such as extinction, no predators, and two populations coexisting in a sustainable manner. The correlation and fluctuation of fear and fear cost were investigated to obtain a better model. The results of the numerical simulations show that the prey population becomes more daring to fight or fighting power with significant prey growth rates or high predator mortality rates. Doi: 10.28991/ESJ-2023-07-02-06 Full Text: PDF
Fusion Landsat-8 Thermal TIRS and OLI Datasets for Superior Monitoring and Change Detection using Remote Sensing
Authors: Dibs Hayder , Ali Alaa Hussein , Al-Ansari Nadhir , Abed Salwan Ali
Published: February 2023

Currently, updating the change detection (CD) of land use/land cover (LU/LC) geospatial information with high accuracy outcomes is important and very confusing with the different classification methods, datasets, satellite images, and ancillary dataset types available. However, using just the low spatial resolution visible bands of the remotely sensed images will not provide good information with high accuracy. Remotely sensed thermal data contains very valuable information to monitor and investigate the CD of the LU/LC. So, it needs to involve the thermal datasets for better outcomes. Fusion plays a big role to map the CD. Therefore, this study aims to find out a refining method for estimating the accurate CD method of the LU/LC patterns by investigating the integration of the effectiveness of the thermal satellite data with visible datasets by (a) adopting a noise removal model, (b) satellite images resampling, (c) image fusion, combining and integrating between the visible and thermal images using the Grim Schmidt spectral (GS) method, (d) applying image classification using Mahalanobis distances (MH), Maximum likelihood (ML) and artificial neural network (ANN) classifiers on datasets captured from the Landsat-8 TIRS and OLI satellite system, these images were captured from operational land imager (OLI) and the thermal infrared (TIRS) sensors of 2015 and 2020 to generate about of twelve LC maps. (e) The comparison was made among all the twelve classifiers' results. The results reveal that adopting the ANN technique on the integrated images of the combined TIRS and OLI datasets has the highest accuracy compared to the rest of the applied image classification approaches. The obtained overall accuracy was 96.31% and 98.40%, and the kappa coefficients were (0.94) and (0.97) for the years 2015 and 2020, respectively. However, the ML classifier obtains better results compared to the MH approach. The image fusion and integration of the thermal images improve the accuracy results by 5%–6% from the proposed method better than using low spatial-resolution visible datasets alone. Doi: 10.28991/ESJ-2023-07-02-09 Full Text: PDF
THE STRUCTURE OF THE OTHER WORLD IN CHARLES KINGSLEY’S “THE WATER BABIES”
Authors:   Russian State University for the Humanities, Vainshtein Olga B.
Published: February 2023

The fairy tale “The Water-Babies” by the British novelist Charles Kingsley depicts the other world as water kingdom. The boy chimney sweeper Tom gets there having drowned in the river. The paper analyses how the other world is organized to provide the Victorian up-bringing and support the ideas of Darwinian evolution. Tom’s life in water is interpreted as the period of moral transformation and the study of nature. The topography of the other world is structured around the magic Isle of St. Brendan. The boundary between this world and the other world is crossed through mirrors, water surfaces and by looking in the eyes of fairies. “The Water-Babies” are interpreted as part of a specific literary tradition. The article compares different versions of the archetypal plot about a chimney sweeper in English literature. The analysis is focused around the poems about the chimney sweeper by William Blake in “Songs of Innocence” and “Songs of Experience”, narrating the tale of children getting into the other world and the following Redemption. “The Three Sleeping Boys of Warwickshire” by Walter de la Mare is the final text in this tradition. In conclusion we examine beliefs about chimney sweeper in folklore sources and in particular the connection between chimney sweeper and good luck.
Aspectos médico legales de heridas cortantes en cuello. Reporte de caso.
Authors: Choez Chiliquinga Edmundo Nicasio , Mar´´ia Zambrano P´´erez , Jos´´e Vizueta Rubio
Published: February 2023

Introducción: Las lesiones por trauma del cuello pueden ser abiertas o cerradas y a su vez se clasifican en superficiales y profundas. La decisión quirúrgica depende de la determinación del compromiso de órganos vitales.
Objetivo: Demostrar la importancia del conocimiento anatómico del cuello para establecer la trayectoria de la herida.
Presentación del caso: Se reporta el caso de un paciente masculino de 27 años, quien recibe herida cortante en el cuello. El  paciente exhibía una herida extensa de tipo superficial en la zona II del cuello, cuya gravedad corresponde al grado 1, por tanto, se suturó la herida, luego se envió al paciente a su domicilio y control posterior para retiro de puntos. Los aspectos médicos legales en el presente caso van encaminados a brindar información relevante respecto al compromiso o no de algún órgano vital o grandes vasos, dicha información facilita al señor fiscal para el establecimiento del  tipo penal.
Discusión: Es importante la presentación del caso ya que nos permite establecer el tratamiento médico que debe recibir el paciente en caso de heridas de cuello y su importancia médico legal para el establecimiento de un delito.
Conclusiones: Para la determinación de la intencionalidad del presunto agresor es fundamental la íntima colaboración entre el fiscal que investiga el caso y el médico perito.
IUS Constituendum of Suistainable Agricultural Policy: The Aftermath of Job Creation Act
Authors: Fahamsyah Ermanto , Chansrakaeo Ruetaitip
Published: February 2023

Agriculture is an important aspect of the life of the Indonesian people. Apart from being a commodity, agriculture is also a part of Indonesian peopleâ€™s lives. In this case, the state needs to enact legal policies related to sustainable agriculture. This study seeks to discuss legal issues in the form of legal disharmony related to sustainable agricultural legal policies. This research is normative legal research. The study results confirm that the disharmony of legal policies related to Sustainable Agriculture has only become a â€œpaper tiger,â€ which means that the rules exist but cannot be implemented because they do not have to implement regulations, so they are difficult to implement. That happens because the respective laws, particularly those related to sustainable agricultural cultivation systems and job creation, which substantially regulate sustainable agriculture, do not refer to each other. That impacts the lack of coordination and horizontal harmonization between fellow laws that substantially regulate sustainable agriculture. Harmonization is also not carried out vertically between Laws and Government Regulations. That occurs when Government Regulations relating to the administration of the agricultural sector do not refer to and harmonize vertically with the Law relating to sustainable agricultural cultivation systems. The results of this study also suggest that in the future, the government, in this case, needs to revise the Government Regulations relating to the implementation of the agricultural sector by incorporating the substance of the Sustainable Agriculture policy as well as being more thorough in harmonizing both vertically and horizontally in drafting legislation.
Interpretasi Dan Implikasi Yuridis Pengaturan Bentuk Badan Hukum Badan Usaha Milik Desa
Authors: Dewi Amelia Sri Kusuma
Published: February 2023

Pasal 78 Ayat (1) Undang-Undang Nomor 6 Tahun 2014 Tentang Desa mengatur bahwa Pembangunan Desa bertujuan meningkatkan kesejahteraan masyarakat Desa dan kualitas hidup manusia serta penanggulangan kemiskinan melalui pemenuhan kebutuhan dasar, pembangunan sarana dan prasarana Desa, pengembangan potensi ekonomi lokal, serta pemanfaatan sumber daya alam dan lingkungan secara berkelanjutan. Dalam rangka melaksanakan pembangunan Desa, Desa dapat mendirikan Badan Usaha Milik Desa. Pasca keberlakuan Undang-Undang Nomor 11 Tahun 2020 tentang Cipta Kerja yang telah menegaskan kedudukan BUM Desa sebagai badan hukum. Penulis selanjutnya melihat adanya isu hukum yaitu apakah Interpretasi Bentuk Badan Usaha Milik Desa Pada Undang-Undang Nomor 11 Tahun 2020 tentang Cipta Kerja peraturan pelaksanaannya, serta implikasi yuridis pengaturan tersebut. Berdasarkan isu hukum tersebut di atas, maka penelitian ini bersifat â€œnormatifâ€ (dogmatik), dengan menggunakan pendekatan yakni : statute approach (pendekatan perundang-undangan). Hasil pembahasan pada penelitian ini adalah bahwa Undang-Undang Nomor 11 Tahun 2020 tentang Cipta Kerja dan peraturan pelaksananya yaitu Peraturan Pemerintah Nomor 11 Tahun 2021 Tentang Badan Usaha Milik Desa telah menegaskan kedudukan BUM Desa sebagai badan hukum, tetapi mengenai apa bentuk badan hukumnya hal ini belum diatur secara jelas dan tegas. Undang-Undang Nomor 11 Tahun 2020 tentang Cipta Kerja justru memuat norma yang membuka ruang multi tafsir mengenai bentuk badan usaha dari BUM Desa dan mengaburkan status BUM Desa sebagai badan hukum publik.
Law Enforcement on Sharia Compliance: a Case Study on The Murabahah Consumptive Financing Agreement of Bank A Syariah
Authors: S Nurjannah , Setiaji Bambang
Published: February 2023

Sharia compliance is the basic basis for assessing whether Islamic banks have enforced sharia law. Law enforcement by Islamic banking must reach the element that the bank has implemented the rules of muamalah related to the prohibition of usury and dzolim. The factual phenomenon is fraud in the murabahah consumptive financing contract by Bank A Syariah. This is important to study and analyze considering that law enforcement on sharia compliance in bank A Syariah on contract and financing instruments has an impact on customer and public trust. This research uses normative legal research methods, with a critical legal study approach. The results of the study show that law enforcement is not directly proportional to sharia compliance. There is still a â€œlegal trickâ€ (Hilah) in the murabahah consumptive financing contract. Hilah is part of the legalization of taking usury. Bank A Syariah business activities have not been maximally carried out in the real or productive sector. Productive sectors, such as livestock, food crop agriculture, food and beverage processing industry, and others. Second, murabahah consumptive financing still relies on the pattern of consumptive lending in the form of a privileged civil servant decree as collateral. The object of the contract is money, not the real sector, so that the murabahah contract fraud by Sharia bank A also surfaced. The murabahah contract that is carried out between BA customers and Sharia bank A is one of the cases that justifies Islamic banks only have sharia labels, but their implementation has not been sharia.
Kepastian Hukum Pendaftaran Persekutuan Komanditer Melalui Sistem Administrasi Badan Usaha Pada Direktorat Administrasi Hukum Umum
Authors: Mustika Yon Surya Anggit Metha , Suryokumoro Herman , Susmayanti Riana
Published: February 2023

Penerapan e-government di Indonesia juga berdampak pada sistem perizinÐ°n, pendaftaran maupun pembubaran suatu Badan Usaha di IndonesiÐ° pun menjÐ°di berubÐ°h yÐ°ng mÐ°nÐ° perubÐ°hÐ°n tersebut sÐ°lÐ°h sÐ°tunyÐ° mengenÐ°i pendÐ°ftÐ°rÐ°n CV di IndonesiÐ°. PerubÐ°hÐ°n yÐ°ng dimÐ°ksud adalah mekÐ°nisme dÐ°ri Sistem ÐdministrÐ°si BÐ°dÐ°n UsÐ°hÐ° dalam Ditjen Adminstrasi Hukum Umum dÐ°lÐ°m melÐ°yÐ°ni pendÐ°ftÐ°rÐ°n badan Usaha salah satunya adalah CV di IndonesiÐ° yÐ°ng mÐ°nÐ° melÐ°lui Sistem ÐdministrÐ°si BÐ°dÐ°n UsÐ°hÐ° sesuai dengan Permenkumham Nomor 17 Tahun 2018. Artikel ini bertujuan untuk mengÐ°nÐ°lisis kedudukÐ°n PerÐ°turÐ°n Menteri Hukum dÐ°n HÐ°k ÐzÐ°si MÐ°nusiÐ° Nomor 17 TÐ°hun 2018 tentÐ°ng PendÐ°ftÐ°rÐ°n PersekutuÐ°n KomÐ°nditer, PersekutuÐ°n Firma, dÐ°n PersekutuÐ°n PerdÐ°tÐ° terhÐ°dÐ°p KitÐ°b UndÐ°ng-UndÐ°ng Hukum DÐ°gÐ°ng sesuÐ°i dengÐ°n hierÐ°rki Peraturan PerundÐ°ng-UndÐ°ngÐ°n di IndonesiÐ° , Ð°kibÐ°t hukum bÐ°gi pendÐ°ftÐ°r Ð°tÐ°u pemilik Persekutuan Komanditer yÐ°ng tidÐ°k mendÐ°ftÐ°rkÐ°n Persekutuan Komanditer nyÐ° pÐ°dÐ° Sistem ÐdministrÐ°si BÐ°dÐ°n UsÐ°hÐ° dÐ°lÐ°m jÐ°ngkÐ° wÐ°ktu yÐ°ng telÐ°h ditentukÐ°n. Serta kepastian hukum pendaftaran Persekutuan Komanditer Melalui Sistem Administrasi Hukum Umum dikaitkan dengan Undang-Undang Informasi dan Transaksi Elektronik. Artikel ini termasuk penelitian hukum normatif dengan Pendekatan Perundang-Undangan Dan Pendekatan Konseptual serta menggunakanTeknik Analisis Data Dengan Logika Deduktif. Hasil Penelitian ini menunjukan bahwa ketentuan didalam Permenkumham Nomor 17 Tahun 2018 bertentangan dengan ketentuan didalam KUHD, menimbulkan beberapa akibat hukum bagi pelaku usaha yang tidak mendaftarkan Persekutuan Komanditernya pada Sistem Administrsi Badan Usaha, serta adanya keterkaitan antara Pendaftaran dalam Sistem Administrasi Badan Usaha dan UUITE yaitu adanya pengakuan secara tegas didalam UUITE terutama mengenai adanya tanda tangan elektronik didalam Surat Keterangan Terdaftar.
Environmental Management and Protection Based on The Green Constitution Concept
Authors: Nur Amalia Ardina , Rahayu Rahayu
Published: February 2023

This study aimed to analyze the green constitution conceptÂ as the basis for environmental protection and management in Indonesia.Â Various problems that occur such asÂ natural disasters, ecosystem damage, and global warming raise concerns and ecological awareness.Â The problem discussed in this research was what is the importance of implementing the green constitution concept and how it is applied in Indonesia.Â This research was normative legal research using secondary data.Â Based on the results of the study, it was concluded that it requiresÂ sustainable development-basedÂ development for the sustainability of human life, as well as other living creatures on earth.Â The program is in line with theÂ concept of theÂ Green Constitution.Â ThisÂ conceptÂ has been embraced by several countries, including Indonesia,theÂ Green ConstitutionÂ concept isÂ adopted in Indonesia with recognition to the concept in the Constitution of the Republic of Indonesia, which is then relegated to laws and regulations under it.
Más allá del binarismo lingüí­stico: propuesta para la descolonización del lenguaje
Authors: Mejí­as Sandia Carlos
Published: February 2023

El presente artículo tiene como objetivo presentar una propuesta teórico-crítica acerca del problema del binarismo de la colonialidad occidental presente en el lenguaje español, a partir de la perspectiva de la descolonialidad lingüística como lectura de la literatura de lingüística (generativista), neurociencia (cognitiva) y del estudio del lenguaje como objeto natural. Se revisa la problemática del binarismo lingüístico y los principales factores involucrados, así como también se exploran las formaciones cognitivo-lingüísticas de la matriz colonial de ordenamiento epistémico y lingüístico para proponer una posible ruptura con este binarismo presente en el lenguaje y lengua, para la búsqueda de unas nuevas lingüísticas que se localicen en unos otros locus de enunciación, que devuelvan a las y los sujetos la ilusión de ser dueños de su decir.
inconstante corregido de Pablo de Olavide, primera bildungsroman hispana y americana conocida
Authors: Muñoz de Morales Galiana Javier
Published: February 2023

El inconstante corregido es la única novela publicada por el limeño Pablo de Olavide, cuya originalidad ha sido confirmada en una investigación reciente que abrió nuevas líneas de investigación a fin de acotar la relevancia exacta de este texto en la historia de la literatura. Con este propósito, y aunque su contenido y su trasfondo ya nos sean conocidos, resulta necesario un análisis de la novela desde el punto de vista formal, lo que la erigiría como pionera en un género sin antecedentes en español. Para ello, se ha utilizado la definición de bildungsroman ofrecida por Miguel Salmerón en su trabajo sobre ese género, y se ha comprobado si el texto de Olavide se adecua a las características de ese tipo de narraciones; a su vez, también ha sido comparado con otras novelas de aprendizaje extranjeras, y con otros textos españoles anteriores a los que se les había asignado ese marbete sin total exactitud. Tales comprobaciones nos permiten afirmar que, en efecto, se trata de la primera bildungsroman hispana —y a un mismo tiempo americana— conocida, y una, además, renovadora y novedosa en el panorama internacional.
The role of celebrity endorsement on purchase intention of ERIGO products
Authors: Siska Abianti  , Lilik Wahyudi
Published: February 2023

This research was conducted to see how celebrities as trusted endorsers can influence consumer purchase intentions and boost sales. In addition, to find out the involvement of celebrity endorsements in encouraging consumers of the Erigo brand which has become a well-known local brand in Indonesia. This study aims to determine the factors that influence purchase intentions for Erigo products. Data were analyzed using PLS-SEM and with a total of 377 respondents spread across Indonesia. The results of this study indicate that celebrity endorsement, brand attitude, and brand loyalty have a positive effect on purchase intention.
Construction project management monitoring system using s-curve
Authors: Joseph Dedy Irawan  , Munasih  , Maria Christina Endarwati  , Renaldi Primaswara Prasetya  , Cindia Rama Auliansyah
Published: February 2023

Every construction project generally has a specific implementation plan and implementation schedule: when to start the implementation of the project, when to complete the project, how to do the project, and how to provide resources. Making a plan for a construction project always refers to the estimates that exist when the scheduled development plan is made. Therefore, problems can arise if there is a mismatch between the plan that has been made and its implementation. With the limited resources in the company, thorough and good planning is needed as a guide in carrying out the project to use resources efficiently and organize work to be completed according to the time specified in the contract. To achieve this goal, the manager controls the project with an s-curve by comparing the actual curve graph with the plan curve graph. The method to be used in monitoring the progress of construction projects is the s-curve. The use of the s-curve method is very supportive because it is suitable for monitoring project progress in terms of performance, cost, and timeliness of project work. The results of this study show that the construction project management monitoring website using the s-curve can create a cost budget plan that follows the contract document, a schedule plan, a weekly project report, and a project report recapitulation. The output results are displayed in the form of a Gantt Chart, and S-curves are completed with plan curve lines and realization curve lines. This project management monitoring website has a multi-user feature so that more than one user can use it.
Studies on the antimicrobial potential of plant extract of banana (Genus Musa) in Indonesia
Authors: Mohammad Kanedi  , Kusuma Handayani  , Wawan Abdullah Setiawan
Published: February 2023

The positive impact of the discovery of antibiotics coupled with advances in the development of antimicrobial drugs has improved human health. Unfortunately, prolonged use of antibiotics has increased microbial resistance. That is why research to find natural ingredients that have the potential to be developed into plant-derived antimicrobial drugs continues to be carried out throughout the world. Among the plants that have been intensively studied for their antimicrobial properties are bananas of the Genus Musa (family Musaceae). In Indonesia, in the last decade there have been quite a lot of studies on the antimicrobial properties of banana plant extracts. Bananas are known to contain a variety of bioactive compounds that are antimicrobial, such as: lycopene, saponins, alkaloids, flavonoids, tannins, phenols, terpenoids, anthocyanins. Microbes that have been proven to be affected with crude extracts of banana plants are fungi such as Trichophyton rubrum, Candida albicans and Pityrosporum ovale and bacteria such as Enterococcus faecalis, Porphyromonas gingivalis, Staphylococcus aureus, Escherichia coli, Lactobacillus plantarum, Klebsiella pneumonia, and Enterococcus faecalis. Therefore it can be concluded that banana plants can be used as a source of plant-derived antimicrobial medicine.
Evaluation of the pre-analytical phase in the central laboratory at Mohammed VI University Hospital of Oujda
Authors: Issam Mokhtari  , Abderrazak Saddari  , Salwa Dahmani  , Imane Naji  , Jalal Abderrahmani  , Mohamed Amine Moumna  , Houcine Sebbar  , Mohammed Choukri
Published: February 2023

In addition to using the most up-to-date analytical technique, a thorough preparation phase must come first in order for the biological examination results to be reliable. The pre-analytical phase is this important step. We decided to conduct a prospective and descriptive study within central Laboratory department of the Mohammed VI University Hospital of Oujda with the goal of evaluating the pre-analytical phase in order to take action on the primary causes of pre-analytical nonconformity. In the course of observing 310 samples, we found 214 instances of pre-analytical nonconformities, of which 62 had to do with the prescription sheet, 62 with patient preparation, 31 with equipment preparation, 37 with the sampling procedure, 22 with waste management. Following the identification of these nonconformities in the hospital services under review, a multitude of corrective and preventive measures were taken in order to meet the standards of International Standard ISO15189 and to ensure the best possible patient care. Indeed, these key initiatives include audits, ongoing education, staff awareness and support.
Evaluation of haematinic activity of Kumara Veeriya Kaantha Chendhuram in phenyl hydrazine induced Anemia in experimental rats
Authors: Sasi Priya. T  , Visweswaran. S
Published: February 2023

The science of medicine is one of the fundamental requirements to well being of humans and their survival. Siddha system is one of the traditional systems of medicine. According to WHO, anaemia is one of the leading causes of death in worldwide. Anaemia is the most common blood disorder, affecting about one third of the global population. In classical Siddha literature, Kumara Veeriya Kaantha Chendhuram is one of the formulation mentioned in Anupoga Vaithiya Navaneetham – part I helps in overcoming iron deficiency anaemia. The ingredients of the formulation include Kaantham (magnetic oxide of iron) and Thara (Mollugo oppositifolia).The present study aims to evaluate haematinic activity by Phenyl hydrazine induced anaemia in animal models. The evaluation was carried out in Wistar albino rats. The effect of standard drug was comparable to those of the test drug. The blood parameters in animals treated with the test drug exhibited a highly statistical significant elevation when compared to control group.
Penyesuaian Perkawinan Pada perempuan yang Menjalani Pernikahan Dini Di Kabupaten Biak Numfor
Authors: Inarkombu Thiara Marthince , Kusumiati Ratriana Yuliastuti Endang
Published: February 2023

Abstract
This study aims to provide an overview of the process of marital adjustment in women who undergo early marriage and what factors influence it. This study used a qualitative research design. Sampling in this study used purposive sampling. The data collection technique was through observation and interviews involving 3 subjects of female sex ranging from 13-19 years of age and marriage age between 1-3 years who live in Biak Numfor district. The results showed that of the 12 marital adjustment tasks, the three subjects had undergone several marital adjustments very well, and there were also several marital adjustment tasks that the three subjects had not done well. The process of marital adjustment is influenced by supporting factors, inhibiting factors and age of marriage.
Keywords: early marriage, marital adjustment
Abstrak
Penelitian ini bertujuan untuk memberikan gambaran proses penyesuaian perkawinan pada perempuan yang menjalani pernikahan dini dan faktor-faktor apa saja yang mempengaruhinya. Penelitian ini menggunakan desain penelitian kualitatif. Pengambilan sampel dalam penelitian ini menggunakan purposive sampling. Teknik pengumpulan data melalui observasi dan wawancara yang melibatkan 3 subjek dengan jenis kelamin perempuan rentang usia 13-19 tahun dan usia perkawinan antara 1 – 3 tahun yang berdomisili di kabupaten Biak Numfor. Hasil penelitian menunjukkan dari 12 tugas penyesuaian perkawinan ketiga subjek sudah menjalani beberapa penyesuaian perkawinan dengan sangat baik, dan juga ada beberapa tugas penyesuaian perkawinan yang masih belum dijalani dengan baik oleh ketiga subjek. Adapun proses penyesuaian perkawinan dipengaruhi faktor pendukung, faktor penghambat dan usia perkawinan.
Kata kunci: pernikahan dini, penyesuaian perkawinan
Perbandingan Tingkat Kepercayaan Diri Ditinjau Dari Jenis Kelamin Pada Siswa SMA Negeri 1 Cerme
Authors: Trimayati Rizka Hadi , Sholichah Ima Fitri , Alfinuha Setyani
Published: February 2023

One of the problems that occurs in high school students today is lack of confidence in their abilities to continue their studies after graduating from high school. The purpose of this study was to find out whether there are differences in the level of self-confidence between male and female students in class XII at SMA Negeri 1 Cerme. The subject of this study was class XII students at SMA Negeri 1 Cerme. A total of 132 students were divided into 66 male students and 66 female students. The data collection technique used self-confidence questionnaire. The hypothesis testing was carried out by analyzing the median test analysis. The results of testing the hypothesis obtained Sig. (2-tailed) 0.001 <0.05, so the hypothesis in this study can be accepted, or it can be said that there is a significant difference in the difference in the level of self-confidence between male and female students.
Peningkatan Hasil Belajar IPA Peserta Didik Kelas VIII Materi Sistem Ekskresi melalui Pengaruh Model STEM
Authors: Herak Rikardus
Published: February 2023

Permasalahan penelitian ini berawal dari perolehan hasil belajar IPA Biologi siswa kelas VIII SMP Negeri 11 Kupang yang belum memuaskan.  Rerata hasil belajar IPA biologi berturut-turut baru mencapai 63,65 selama dua tahun ini. Rerata hasil belajar tersebut berdampak pada rendahnya pencapaian KKM berturut-turut baru mencapai 38%, 41%. Berdasarkan permasalahan ini akan dilakukan perbaikan pada proses pembelajaran agar hasil belajar dan capaian KKM dapat ditingkatkan. Penelitian ini merupakan penelitian kuantitatif dengan metode kuasi eksperimen. Penelitian ini dilakukan dua kelas yaitu kelas perlakuan dan kelas kontrol. Sampel penelitian ini peserta didik kelas VIII B sebagai kelas eksperimen sedangkan siswa kelas VIII D sebagai kelas kontrol. Instrumen penelitian yang digunakan adalah lembar tes hasil belajar, lembar pengamatan aktivitas peserta didik dan lembar pengamatan kemampuan guru dalam pengelolaan pembelajaran. Teknik pengumpulan data melalui observasi dan Tes. Teknik analisis data menggunakan analisis deskriptif dan inferensial. Hasil penelitian menujukkan rata-rata hasil belajar peserta didik terjadi peningkatan yaitu model STEM dari 54,52 menjadi 88,68 peningkatan sebesar 34,16, pembelajaran langsung dari 48,12 menjadi 70,33 peningkatan sebesar 22,21. Rata-rata reliabilitas aktivitas peserta didik model STEM adalah 83,68 %, dan model pembelajaran langsung 72,89%. Rata-rata reliabilitas pengelolaan model STEM adalah 96,42% dan pembelajaran langsung 81,58%.
Pembelajaran Sains Anak Usia Dini dengan Model Pembelajaran Children Learning In Science
Authors: Wijaya Komang Wisnu Budi , Dewi Putu Ayu Septiari
Published: February 2023

Sains memberikan manfaat besar dalam kehidupan manusia dan bahkan setiap hari manusia tidak luput dari fenomena sains. Oleh karena itu pembelajaran sains hendaknya diberikan sejak anak usia dini. Namun, fakta di lapangan menyatakan bahwa pembelajaran sains anak usia dini belum optimal karena guru hanya mengandalkan teks dan penugasan. Dengan demikian diperlukan sebuah model pembelajaran yang inovatif yaitu model pembelajaran Children Learning in Science. Penelitian ini mencoba mengkaji cara melaksanakan pembelajaran sains bagi anak usia dini menggunakan model Children Learning in Science. Penelitian ini termasuk dalam penelitian studi literature. Data didapatkan dari berbagai sumber berupa buku, jurnal dan karya ilmiah lainnya. Teknik analisis data menggunakan teknik analisis isi. Hasil penelitian menyatakan bahwa model pembelajaran Children Learning in Science layak digunakan dalam pembelajaran sains anak usia dini karena memungkinkan anak berinteraksi langsung dengan fenomena sains yang konkret dan belajar sains dengan menyenangkan. Model pembelajaran Children Learning in Science juga sesuai dengan ruang lingkup pembelajaran sains yaitu sebagai produk, proses dan sikap.
Pengaruh Likuiditas, Leverage, dan Konservatisme Akuntansi Terhadap Kualitas Laba
Authors: Ersa Amanda Maulida  , Dirvi Surya Abbas  , Imam Hidayat  , Hamdani Hamdani
Published: February 2023

Tujuan dari penelitian ini untuk menguji dan menganalisis pengaruh likuiditas, leverage dan konservatisme akuntansi terhadap kualitas laba. Populasi dalam penelitian ini adalah perusahaan pertambangan yang terdaftar di Bursa Efek Indonesia periode 2017-2021. Teknik pengambilan sampel dengan menggunakan teknik purposive sampling menghasilkan 45 observasi perusahaan. Teknik analisis yang digunakan yaitu analisis statistik deskriptif dan analisis statistik inferensial dengan uji interaksi moderated analysis regression sebagai analisis regresi moderasinya. Hasil pengujian hipotesis menunjukkan bahwa likuiditas dan konservatisme akuntansi tidak berpengaruh terhadap kualitas laba, serta leverage berpengaruh terhadap kualitas laba.
PENGARUH LIKUIDITAS, SALES GROWTH DAN UKURAN PERUSAHAAN TERHADAP FINANCIAL DISTRESS
Authors: Beby Ratna Sari  , Dirvi Surya Abbas  , Hesty Ervianni Zulaecha  , Imas Kismanah
Published: February 2023

Every company that stands and exists in the business world is to get profit, another important thing is to survive in the business world. Many things and obstacles are often faced by a company to maintain its existence. Therefore the researchers conducted this research with the aim to determine the effect of liquidity, sales growth and company size on financial distress. The method used in this research is panel data Regression data management, with Eviews 12 as a data processing tool. The data collection technique itself uses purposive sampling and the data used is secondary data. The population of this study are consumer industry companies listed on the IDX in 2017-2022. The results of this study are that liquidity and company size have an insignificant positive effect and sales growth has an insignificant negative effect on financial distress.
PENGARUH PENGALAMAN KERJA DAN TINGKAT PENDIDIKAN TERHADAP KINERJA GURU SMP NEGERI I AROSBAYA KABUPATEN BANGKALAN YANG DI MEDIASI OLEH KEMAMPUAN KERJA
Authors: Nurul Qomariyah  , Chamariyah Chamariyah  , Subijanto Subijanto
Published: February 2023

The results showed that: 1) Work experience had a significant positive effect on teacher performance with an original sample value of 0.244. 2) Work experience has a significant positive effect on work ability with the original sample value of 0.570. 3) Education level has a significant positive effect on work ability with the original sample value of 0.335. 4) Education level has a significant positive effect on teacher performance with the original sample value of 0.326. 5) Work ability has a significant positive effect on teacher performance with the original sample value of 0.417. 6) Work experience has a significant positive effect on teacher performance mediated by work ability with an original sample value of 0.238. 7) Education level has a significant positive effect on teacher performance mediated by work ability with the original sample value of 0.140.
Determinan Turnover Intention Karyawan Coffee Shop Di Semarang
Authors: Nihlatul Laeli  , Ana Kadarningsih
Published: February 2023

Penelitian ini memiliki tujuan untuk melihat pengaruh compensation, job satisfaction, dan motivation terhadap turnover intention. Objek dari penelitian ini adalah karyawan yang bekerja di 30 coffee shop Semarang. Pengumpulan data dilakukan dengan studi pustaka dan membagikan kuesioner ke karyawan coffee shop. Jawaban kuesioner dari responden sebanyak 182 jawaban, tetapi hanya 141 data yang dapat diolah dikarenakan normalitas data tidak mencapai batas normalitas 0.05. Metode analisis data dalam penelitian ini adalah analisis deskriptif, uji normalitas data, analisis regresi linier berganda, dan uji koefisien determinasi (R²). Alat atau aplikasi yang digunakan untuk menganalisis data dalam penelitian ini adalah software SPSS v.22. Hasil dari penelitian ini memperlihatkan bahwa variabel compensation tidak memiliki pengaruh signifikan terhadap turnover intention, variabel job satisfaction menunjukkan hasil yang signifikan positif terhadap turnover intention, sedangkan variabel motivation menunjukkan hasil yang signifikan negatif terhadap turnover intention.
PENGARUH PENGALAMAN KERJA, FASILITAS, KOMUNIKASI DAN KEPUASAN KERJA TERHADAP PRODUKTIVITAS KERJA KARYAWAN BAGIAN PRODUKSICV ANEKA SUKSES
Authors: Fitria Novitas Sari  , Aprilia Dian Eva Sari  , Edi Murdiayanto
Published: February 2023

Penelitian ini bertujuan untuk mengetahui pengaruh pengalaman kerja, fasilitas, komunikasi, kepuasan kerja terhadap produktivitas kerja di CV Aneka Sukses. Jenis penelitian ini adalah penelitian kuantitatif. Teknik pengumpulan data, data primer dan data sekunder. Pemilihan sampel menggunakan metode purposive sampling, diperoleh sebanyak 40 responden. Data diperoleh melalui kuesioner, wawancara, studi literatur. Teknik analisis yang digunakan adalah Uji Validitas, Uji Reliabilitas, Uji Asumsi Klasik, Analisis Regresi Linier Berganda, Uji t dan Uji Koefisien Determinasi. Hasil uji-t pengalaman kerja berpengaruh signifikan terhadap produktivitas. Fasilitas memiliki pengaruh yang signifikan terhadap produktivitas. Komunikasi memiliki pengaruh yang signifikan terhadap produktivitas. Kepuasan berpengaruh signifikan terhadap produktivitas. Hasil uji F dapat disimpulkan bahwa Pengalaman, Fasilitas, Komunikasi dan Kepuasan berpengaruh secara simultan dan signifikan terhadap produktivitas.
ANALISIS PENDAPATAN PG.XYZ DI JAWA TIMUR
Authors: Mohammad Ali Masruri  , Anita Handayani
Published: February 2023

This study purpose to know the company’s income PG. XYZ East Java company. Income analysis is used to know whether the business development is increasing or decreasing. Considering the income earned affects to the survival of the company. The type of research used is descriptive qualitative research. Data analysis method is used quantitative methods, namely descriptive analysis. The evaluation results show that the average net income earned by the East Java PG.XYZ sugar business is IDR 362,862,000/year or IDR. 30,238,500/month and the sugar business run by PG. XYZ East Java is profitable. It can be seen from the acquisition of a ratio analysis of more than 1, namely 1.21. Therefore, it is hoped that PG. XYZ East Java will continue to develop its sugar business and increase sales volume so that its income will also increase.