bluuebunny/crossref_metadata_2025 huggingface dataset:
How Indonesia media deal with Sustainable Development Goals
Authors: Irwansyah Irwansyah
Published: December 2018

After millennium development goals end it terms in 2015, members of United Nation agree to create new sustainable development goals (SDGs). The media are endorsed and needed to involve in the implementation of SDGs. Moreover, media in all its forms has a crucial role to play in the development agenda to ensure that citizens are well informed. The media has important roles to play, to inform, to educate, and to provide a platform for public debate and discussion. The media could serve as catalyst for citizens’ empowerment and help to hold government and authorities to account. This study focuses on how media deal with its agenda setting in order to spread the information of SDGs to wider public. Based on theoretical assumption of the study, this study examines the media coverage of SDGs in 2017/2018; how SDGs has been understood and framed by media. By using a sequential mixed-method, this study applies quantitative approach to analyze all articles on SDGs. The qualitative approach is conducted to explore deeper insight of SDGs understanding from news management. This study found that not all SDGs are informed well. Only several SDGs are framed based on the concern of public policy.
Why should we save water? Education on water conservation for villagers of Tianyar, Bali
Authors: Adhariani Desi
Published: December 2018

This study examined the household water conservation program for villagers of Tianyar, Bali who experienced water scarcity in arid regions. The educational program consists of several activities followed by three focus group discussions to develop community awareness on the methods to save water for household consumption. The results indicate the rising awareness among villagers on the importance of water conservation and methods to save water while maintaining the healthy living standard.
Analysis on the management of waste domestic system in populous neighborhoods
Authors: Zahra Shabrina Arika
Published: December 2018

Population growth increases the disposal of domestic wastewater generated by the community. Residents who live in neighborhoods and slums have become one of the factors of domestic wastewater issues. These communities urinate and defecate in inappropriate locations without any post-processing, including simple processing through septic tanks. These issues can be resolved by improving the domestic wastewater management. The centralized domestic wastewater management system is one of the solutions for the management of alternative settlements and slums in RT 09, Bidara Cina. This research aims at planning domestic waste management model that fits into the community. This research will use descriptive analysis methods with quantitative approach. Data are obtained through field surveys and resident interviews. The data then are presented in a table. My contribution will provide a suitable model for domestic wastewater management planning. The findings of this study refer to six (6) SDGs, namely clean water and sanitation to ensure domestic wastewater management and sustainable sanitation.
Shade-grown coffee under fruit trees in highland forests as part of an environmental village restoration
Authors: Sudaryanto  , Variasa Thomas Oni
Published: December 2018

Highland forest areas upstream of the Ciliwung watershed are part of the Bogor Regency. Land use change is a serious issue which needs to be addressed. Community Based Forest Management was initiated by the Forestry State Enterprise to benefit highland agroforestry. The program aims to reduce forest degradation and provide economic opportunities for communities around the forest to be involved in the management system. The program was implemented in Kampung Cibulao, Tugu Utara Village, Bogor Regency. It has involved the management of village forests by forest farmer groups since 2009. This study aims to determine the impacts of the program on improvement of the local economy and land productivity. Field observations and interviews with forest farmer groups were conducted to collect primary data. The aspects analysed were : 1) the economic impact ; and 2) the positive impact of the shade-grown coffee in supporting forest restoration and land conservation. The study indicates that there has been a significant revenue increase of between 63.0% from cherry production (IDR630,000/hectare/month) to 127.5% from green bean production (IDR 1,275,000/hectare/month) through shade-grown coffee management. Furthermore, the direct benefits of forest management can aid community understanding and encourage collective action in forest restoration and land conservation.
Does water and sanitation effects on children’s physical development? Evidence from Indonesia Family life Survey (IFLS) 2014
Authors: Hasanah Israul , Susanti Hera
Published: December 2018

Chronic malnutrition (Stunting) is one of the most serious health problems in Indonesia. Almost 8.9 million or 37.2 % of all Indonesian children under 5 were stunted in 2013. The negative impact as a result of stunting in early of life associated with high mortality, decrease cognitive development, poor school performance, and reduce productivity as adults. Stunting associated with long-term nutrition intake and the burden of diseases. Around 56 % of malnutrition is associated with inadequate water, sanitation and hygiene. Conversely Investing to increase safe drinking water and proper sanitation provides many benefits for eliminating stunting. This paper analyzes how a poor water and sanitation affect a child’s stunting in Indonesia. Using logistic regression methods and large-scale data from the Indonesia Family Life Survey (IFLS) 2014, we selected 2835 children aged 0-5 years old in 2014 who considered stunting. The study finds that they are significantly associated between proper sanitation and number of stunting under 5. Children who live in a household with lack sanitation have the possibility of stunted 0.645 times higher than children living in the household with proper sanitation. While children living in unprotected water more likely to being stunted 0.874 times but statistically significant.
The analysis of the implementation of the program of development of community empowerment around the coal mining sites
Authors: Utami Marikha Ulfah , Saria Lana
Published: December 2018

Along with the significant increase of world coal price reaching US$ 100.69/ton, it can be affects the increase of coal production in Indonesia. On the other hand, coal mining activities cause a number of social and environmental conflicts.. This study examines the implementation of community-based environmental development and empowerment programs and synergies between the Central Government, Regional Governments, Entrepreneurs, and Communities around the mine and and also Community Development costs. The results of interviews and analysis of primary data, the implementation of Community Development carried out by the Company is guided by the Mineral and Coal Law and its implementing regulations such as Government Regulation Number 23 of 2010 concerning the Implementation of Mineral and Coal Mining Business Activities. The results regression statistic showed relationship between variable (R2=67%), and also equation formula Community Development Costs = 979.296.927,41 + 0 (Operational Costs) + 858,95 (Coal Productions). Coal Production influences the Community Development Cost variable and the effect is positive. Because the regression coefficient on coal production is positive, which means that if the coal production increases, the Community Development costs will increase.The implementation model of community empowerment programs includes increasing infrastructure and infrastructure, Increased real income, and increased economic independence.
S-LCA applications: a case studies analysis
Authors: Lucchetti Maria C. , Arcese Gabriella , Traverso Marzia , Montauti Chiara
Published: December 2018

S-LCA is defined by the guidelines established by the 2009 UNEP/SETAC, as "a technique for assessing social (real or potential) impacts with the aim of evaluating the socio-economic aspects of the products and their potential impacts, positive and negative, along their life cycle, including the extraction and processing of raw materials, production, distribution, use, reuse, maintenance, recycling and final disposal"[1]. In addition, the S-LCA follows the same structure presented in the ISO 14040-14044 (2006) standards for the Life cycle assessment method[2][3]. The number of case studies that emerge from the literature show that this tool is a significant success among the scientific community and industrial sector. Based on a systematic review of the literature conducted on the case studies reported in the literature between 2013-2017 based on 48 case studies, we have been carried out and mapped some productive sectors such as the agri-food sector, automotive, metal and textile. This analysis has made it possible to highlight how, especially in the last 2 years, the application to the practical cases of the S-LCA methodology has been increased, as well as the number of integrated use of the two environmental LCA and S-LCA instruments, allowing so the application also to SMEs.
Using life cycle inventory to improve the sustainability of traditional market management: a case study in Pandansari Market Balikpapan and Ibuh Market Payakumbuh
Authors: Mangkara Sessario Bayu , Hasibuan Hayati Sari , Chairani Ellyna
Published: December 2018

Indonesia has 13,450 traditional market with 12.6 million traders in 2016. This type of markets has significant role and contribution for the national economic, the traders and the consumers. This research aims to investigate the sustainability of business model in traditional market. Study area are Pasar Pandansari in Balikpapan and Pasar Ibuh, Payakumbuh. Using the LCA methods, this study adopts some phases of International Standard Organization (ISO) 14040 consisting of setting up the goal and scope, and data inventory. Identified inputs include electrical energy, water, and materials/goods to sale. In addition, this study also investigates the economic aspect through the identification of the retribution income to the local government or management and environmental impacts. This study found that Pandansari Market has more extravagant inputs, especially in the consumption of electrical energy 78.5 kW/month (market stall) and 1,217 kW/month (kiosk) and this has an impact on environmental pollution through the exploitation of electrical energy in traditional market environments. The policy of using lights and electronic devices that have low kW and applying the concept of reward and punishment to traders can improve the sustainability of traditional market management.
Developing a characterization factor framework for microbial contamination
Authors: Wardani Ira
Published: December 2018

Life Cycle Impact Assessment (LCIA) can be used as a method to assess environmental impact of pathogen contamination in several stages. This paper attempts to determine the characterization factor (CF) for microbial contamination from livestock emission in surface water on a global scale. CF was defined as the change in Disability Adjusted Life Years (dDALY in yr) due to a marginal change in emission of a pathogen (dOocyst/day). This CF consists of intake fraction, effect factor and damage factor. The average intake fraction per river basin specific is 0.003, meaning that 0.3% of the emitted oocysts is emitted by the human population via drinking water and swimming. The effect factor value has a range from 0.0022-0736 case/oocyst, with the average 0.29 case/oocyst. The final characterization factor has a range between 0 to 1.2 x 10-5 DALY/oocyst in a river basin scale. In this study, CFs was determined for pathogen contamination for the first time. It was shown how these can be derived for Cryptosporidium and other pathogen with similar cause-impact pathways.
Aléa vibratoire dans les sols : indicateurs pertinents et classification simplifiée
Authors: Jamal-Eddine Abdul-Karim , Lenti Luca , Semblat Jean-François
Published: December 2018

La caractérisation de l’aléa sismique constitue un enjeu majeur dans le domaine du génie civil. En ingénierie des vibrations, il n’existe pas de domaine d’étude similaire bien que cette question soit décisive pour la prédiction de l’impact et de la gêne occasionnée (population, environnement, ouvrages, industrie de pointe). Cette caractérisation passe nécessairement par la connaissance des diverses sources de vibrations : exploitation des infrastructures (ferrées et routières), travaux de construction ou de rénovation (vibrofonçage, battages). Elle dépend fortement du mode de propagation des ondes mécaniques entre la source et le récepteur selon les sols (sites) et leur stratification. La nocivité des vibrations (i.e. capacité à occasionner des dégâts) dépendra donc du type de source, de la propagation, mais également de la réponse dynamique du récepteur exprimée en fonction de ses propriétés modales. Dans cet article, des simulations numériques sont combinées à des enregistrements de vibrations, liées à l’exploitation d’infrastructures ou engendrées par des chantiers. Dans l’hypothèse de sols à comportement viscoélastique et pour une configuration stratigraphique donnée, les niveaux de vibrations envisageables à la surface libre s’estiment en fonction de la distance à la source. Les enregistrements considérés permettent d’identifier des indicateurs pertinents et de proposer une classification simplifiée des sources et des sites. On combine ainsi les caractéristiques spectrales des sources (représentées par leur Transformée de Fourier) et la propagation entre la source et le récepteur au moyen d’une fonction de transfert (rapport spectral entre vibration à une distance donnée et celle au niveau de la source). La correspondance entre les propriétés spectrales des sources et celles d’un site donné est quantifiée par le facteur d’immunité (IMF) indépendamment du récepteur à considérer. Cette quantification représente l’ « aléa vibratoire » qui indique le niveau vibratoire attendu en entrée au niveau du récepteur. Ceci est similaire à la définition de l’aléa sismique utilisée dans l’Eurocode 8 pour les études de dimensionnement et renforcement sismique. En utilisant les paramètres comme le gradient de vitesse et le contenu spectral des enregistrements, les effets induits ont été analysés pour de multiples sources. Des indicateurs pertinents (vitesse moyenne à faible profondeur et gradient de vitesse) sont introduits afin de proposer une classification simplifiée de l’aléa vibratoire pour les différentes sources considérées. En cas d’absence de mesure pour une source et un site donnés, cette classification empirique pourra être utilisée afin d’estimer le niveau vibratoire attendu en entrée d’un récepteur.
Physical and Mechanical Properties of Lightweight Expanded Clay Aggregate (LECA)
Authors: Zukri Azhani , Nazir Ramli , Said Khairun Nissa Mat , Moayedi Hossein
Published: December 2018

Lightweight aggregate is the generic name of a group of aggregates having a relative density lower than normal aggregates (natural sand, gravel, and crushed stone), sometimes is referred to as low density aggregate. Depending on the source and the method of production, lightweight aggregates exhibit considerable differences in particle shape, texture and properties. Lightweight expanded clay aggregate (LECA) is among the common lightweight materials that have been applied successfully in civil engineering works. Many studies have been conducted to investigate the performances of LECA used in structural and geotechnical applications. They are favourable materials used in projects where weight is an issue because the materials can help reduce dead loads and lateral forces by more than half in installations over structures and those with soft soils. LECA is an eco-friendly nature-based waste product that combines the same benefits as brick tiles. LECA is indestructible, non-combustible, and impervious to attack by dry-rot, wet-rot and insects. This paper focused on the properties of LECA aggregates supplied by LEXCA Sdn. Bhd. through laboratory tests in accordance to the standard specifications. The properties of several LECA produced from different country and production plants are also reviewed for comparative purpose. In addition, the material properties evaluated from previously conducted research also was discussed. It was found that, even though LECA was produced from the same raw materials, it has certain range of property values. The properties of LECA shows their suitability and potential for replacing natural aggregates in many civil engineering works. It is hoped that, the properties presented in this paper could help others who conduct study especially numerical analysis using LECA as geotechnical materials.
Finite element analysis of high strength reinforced concrete beams
Authors: Oh CL , Lee SW , Mohd Raizamzamani MZ , Azerai AR , Norrul Azmi Y
Published: December 2018

Development of high strength concrete as a new ecological construction material to sustain the gradually expanding construction industry has arisen. This paper presents nonlinear finite element analysis of three-dimensional high strength reinforced concrete beams using ABAQUS. The uniaxial compressive strength for the beam models were taken from the existing experimatal data on high strength concrete cubes. Eurocode 2 was also used to establish material parameters for the constitutive models for concrete and reinforcing bars. In this study, two 150mm x 200mm x 1200mm simply supported rectangular concrete beam models subjected to loads at different shear span to effective depth ratios (a/d = 1.0 and 2.0) were analysed. Numerical results were validated with the existing experimental data specifically on the load-deflection responses and von mises stresses. It was found that the finite element results show greater than 70% agreement with the experimental results.
Impact of forest conversion to agricultural plantation on soil erosion
Authors: Mohamad Nur Athirah , Jamal Mohamad Hidayat , Annammala Kogila Vani , Yusop Zulkifli , Alias Nor Eliza , Sugumaran Dhinesh
Published: December 2018

Agriculture in Malaysia makes up to twelve percent of the nation’s GDP and is supplying one-third of the world rubber export. Ambitious agriculture demand increases the intensity of forest conversion which is driven to the soil erosion. Thus, this study is to measure and analyse the impact of forest conversion on soil erosion relate to some manipulated variables such as slope, bulk density, soil moisture, canopy openness and ground cover, where rainfall and soil type are constant within the sites. Two different land-uses of High Conservation Value Forest (HCVF) and Mature Rubber Plantation of Timber Latex Clone (MRP) were selected around Kelantan state, due to the high land conversion compared to the other states of West Malaysia. Ground height change was monitored by using Modified Laser Erosion Bridge (MLEB) in between 17 to 48 transects. The result found that the annual soil erosion rate was 76.12 t.ha-1.yr-1 for HCVF is higher compared to the MRP was 6.37 t.ha-1.yr-1. Terrace soil conservation technique is practiced for MRP helps in reducing soil movement resulted significant low erosion rate compared to the HCVF. The results indicate that even a relatively limited forest conversion can be assumed to have a significant effect on regional soil erosion rate.
The use of human hair in green technology to reduce human-wild hog conflict from the agricultural perspective
Authors: Kamsano Nur Suraya , Sohaili Johan , Supian Nur Sumaiyyah , Kumari Muniyandi Shantha , Md Din Mohd. Fadhil
Published: December 2018

Human scalp hair (HSH) waste has often dumped without undergoing any proper treatment or even being reused. Past studies related to this waste in Malaysia is still not as wide as in others countries. However, in some rural areas, this waste is still used by farmers as pest controller to protect plantation from wild hog attacks. Unfortunately, the past practices does not expose their effectiveness as repellent. This study briefly discuss on the human-wild hog conflict, current practices used to control the invasive activity and to share the result of using HSH as repellent to help farmer of small orchid in Muar, Johor. In this pilot study, HSH were washed using the non-ionic detergent-acetone method as prior treatment to remove all impurities that might stick on them. In order to increase the probability of visitation, fermented corn bait has been used to lure the wild hog into the target area. Four (4) samples (A) 5kg whole corn; (B) 5kg whole corn mixed with 20g HSH; (C) 5kg whole corn mixed with 40g HSH; and (D) 5kg whole corn mixed with 60g HSH have been set on the private orchid and observed. The 5-day test indicates the potential of HSH as temporary wild hog repellent.
Klinischer Verlauf nach stationärer psychosomatischer Behandlung – Ergebnisse einer naturalistischen Einjahreskatamnese
Authors: Valdés-Stauber Juan , Krämer Sabine , Bachthaler Susanne
Published: December 2018

Die Effektivität der stationären psychosomatischen Behandlung wurde in verschiedenen Settings belegt. Die Frage der Nachhaltigkeit der erreichten Besserung und der prognostischen Faktoren ist von versorgungsmedizinischer Bedeutung.

Untersucht wird primär, inwieweit sich der klinische Zustand von Patienten ein Jahr nach ihrer Entlassung aus der stationär-psychosomatischen Behandlung im Vergleich mit dem Status zum Entlasszeitpunkt verändert hat. Sekundär, inwiefern sich versorgungsbezogene Variablen im Vergleich zum Jahr vor der Indexaufnahme verändern.

Einjahreskatamnese des naturalistischen Verlaufs einer Stichprobe. Die Daten werden anhand von 5 klinischen, 3 ressourcenbezogenen, 1 verlaufseinschätzenden und 3 versorgungsbezogenen Variablen erhoben. Dabei werden 4 Messzeitpunkte berücksichtigt: Aufnahme mit Einwilligung in die Untersuchung (N = 262), Entlasszeitpunkt (N = 249) sowie 6 Monate (N = 148) und 12 Monate (N = 114) nach der Entlassung. Prä-post-Unterschiede wurden mit t-Tests und Assoziationen mittels multivariater linearer und logistischer Regressionen untersucht.

Die Patienten, die Angaben zum Katamnesezeitpunkt machten, unterschieden sich in den stationär erhobenen Daten nicht von denen, die nicht antworteten. Ein Jahr nach der Entlassung bestanden weiterhin hochsignifikante Unterschiede zum Aufnahmezeitpunkt und keine statistische Verschlechterung verglichen mit dem Entlasszeitpunkt. Die subjektive globale Einschätzung des Verlaufs war bei 76 % positiv; anders bei den einzelnen Tests. Die weitere Behandlung erfolgte vorwiegend durch Psychotherapeuten (78 %), Hausärzte (63 %) und Psychiater (44 %). Zwischen Psychotherapie(dichte) und klinischen Variablen bestehen relevante Zusammenhänge.

Ein Jahr nach der Entlassung hält die stationär erreichte klinische Besserung durchschnittlich an. Dies könnte ein Hinweis für die mittelfristige Effektivität stationärer psychosomatischer Krankenhausbehandlung sein. Die subjektive globale Einschätzung des Verlaufs fällt positiver aus, als es die detaillierten Ergebnisse anhand standardisierter Fragebögen abbilden, weshalb beide Erfassungsmethoden zu berücksichtigen sind. Es ergeben sich Hinweise, dass psychotherapeutische Weiterbehandlung zu günstigeren Verläufen führen könnte.
Utility of “liquid biopsy” using pancreatic juice for early detection of pancreatic cancer
Authors: Okada Tetsuhiro , Iwano Hirotoshi , Ono Yusuke , Karasaki Hidenori , Sato Takayuki , Yamada Masataka , Omori Yuko , Sato Hiroki , Hayashi Akihiro , Kawabata Hidemasa , Goto Takuma , Sasajima Junpei , Takauji Shuhei , Nagashima Kazuo , Mizukami Yusuke , Okumura Toshikatsu
Published: December 2018

Background Despite advances in the diagnosis of pancreatic ductal adenocarcinoma (PDA), histological evaluation of small and poorly defined masses in the pancreas is uncomfortable and unsafe.

Methods We herein report a case of early stage PDA, in which multiple KRAS mutations were detected in the pancreatic juice preoperatively. A small hypoechoic area adjacent to the portal vein was detected through endoscopic ultrasound in the pancreatic body. KRAS mutations were evaluated using plasma, and the pancreatic juice by digital PCR.

Results Pancreatic duct biopsy and pancreatic juice cytology were performed with no evidence of malignancy; however, KRAS mutations, KRAS G12V and G12D, were detected in the pancreatic juice. Histological assessment of the resected specimen demonstrated a solid tumor with desmoplastic reaction accompanied by carcinoma in situ in the main pancreatic duct where KRAS G12V mutation was identified. More detailed analysis demonstrated KRAS G12D mutation in the cluster of low grade pancreatic intraepithelial neoplasia, implying that the lesion developed independently.

Conclusions Our study indicates the potential of “endoscopic liquid biopsy” to capture the driver gene for PDA diagnosis.
From Bioactive Pyrrolidino[3,4-c]pyrrolidines to more Bioactive Pyrrolidino[3,4-b]pyrrolidines via Ring-Opening/Ring-Closing Promoted by Sodium Methoxide
Authors: Dondas H. , Sansano José , Belveren Samet , Larrañaga Olatz , Poyraz Samet , Ülger Mahmut , Şahin Ertan , Ferrándiz-Saperas Marcos , de Gracia Retamosa M. , de Cózar Abel
Published: December 2018

The process involving a rearrangement of pyrrolidino[3,4-c]pyrrolidine to another pyrrolidino[3,4-b]pyrrolidine using sodium methoxide as base is fully studied. The effects of the substituents are analyzed during the ring-opening/ring-closing sequence. Computational studies are also performed to explain the importance of susbstituents and quaternary carbons, especially when the (3-indolyl)methyl is present in the starting material. Finally, all the samples are evaluated as potential candidates for antibacterial and antimycobacterial activities.
Enantioselective Synthesis of Tertiary Trifluoromethyl Carbinols by Vinylogous Aldol Reaction of 3-Methylcyclohex-2-en-1-one with (Het)aryl Trifluoromethyl Ketones
Authors: Han Xiaoyu , Chen Fenfen , Chang Zhixin , Paidamoyo Chigumbu , Zeng Xiaofei , Wang Yongjiang
Published: December 2018

A direct enantioselective vinylogous aldol reaction of trifluoromethyl ketones with 3-methylcyclohex-2-en-1-one through hydrogen-bond-directing dienamine catalysis by a diamine–sulfonamide catalyst has been demonstrated. A range of trifluoromethylated tertiary alcohols were efficiently produced in yields of up to 86% and with 93% enantioselectivity.
Comparative Histomorphology of the Ovary and the Oviduct in Rabbits and Pigeons
Authors: Ishaya Helga , Omaga Imelda , Dibal Nathan , Attah Martha
Published: December 2018

Introduction Knowledge of the evolutionary relationship between different classes of vertebrates can be obtained through a comparative study of their structures, forms, functions, and of the mode of development of the structures. Birds and mammals are vertebrates with different modes of reproduction, that is, oviparity in birds and viviparity in mammals. The aim of the present study is to compare the histomorphology of the ovaries and of the oviducts/uterine tubes in rabbits and pigeons. The present study highlights the histological and morphological differences that bring about the production of eggs in birds and the production of fully developed fetuses in mammals.

Materials and Methods Five rabbits and five domestic pigeons were anesthetized with chloroform and sacrificed. The ovaries and the oviducts/uterine tubes were dissected and fixed in Bouin fluid and processed for a light microscopic study.

Results The result showed paired ovaries and uterine tubes in rabbits that unite at the isthmus to form a single uterus that opens into the vagina, with only the left ovary and oviduct appearing as a compact body with distinct infundibulum, magnum, isthmus, uterus and vagina in pigeons. Photomicrographs of the ovaries of rabbits showed parenchyma cells with primary follicles, while the ovaries of pigeons showed developing follicles and yolk granules. Both the oviducts of rabbits and of pigeons showed a highly folded mucosa with a thick muscular wall.

Conclusion The differences observed in the structures of the ovaries and of the oviducts of rabbits and pigeons might be due to their different reproductive functions in parturition (viviparity and oviparity, respectively).
Imaging Description of Extragenital Müllerian Adenosarcoma: A Case Report
Authors: Mone Annalisa , Iannone Piergiorgio
Published: December 2018

Müllerian adenosarcoma is a very rare gynecological disease, comprising 5% of uterine sarcomas. Extragenital localizations are even rarer. We report a very interesting case of a 27-year-old woman complaining of pelvic pain, with a subsequent diagnosis of extragenital Müllerian adenosarcoma. This is the first case reported in the literature with a complete and wide imaging description. Even if rare, Müllerian adenosarcoma should be hypothesized in case of young female patients presenting with suspicious pelvic mass.
Communicating with Vulnerable Patient Populations: A Randomized Intervention to Teach Inpatients to Use the Electronic Patient Portal
Authors: Stein Jacob , Klein Jared , Payne Thomas , Jackson Sara , Peacock Sue , Oster Natalia , Carpenter Trinell , Elmore Joann
Published: December 2018

Background Patient portals are expanding as a means to engage patients and have evidence for benefit in the outpatient setting. However, few studies have evaluated their use in the inpatient setting, or with vulnerable patient populations.

Objective This article assesses an intervention to teach hospitalized vulnerable patients to access their discharge summaries using electronic patient portals.

Methods Patients at a safety net hospital were randomly assigned to portal use education or usual care. Surveys assessed perceptions of discharge paperwork and the electronic portal.

Results Of the 202 prescreened eligible patients (e.g., deemed mentally competent, spoke English, and had a telephone), only 43% had working emails. Forty-four percent of participants did not remember receiving or reading discharge paperwork. Patients trained in portal use (n = 47) or receiving usual care (n = 23) preferred hospitals with online record access (85 and 83%, respectively), and felt that online access would increase their trust in doctors (85 and 87%) and satisfaction with care (91% each). Those who received training in portal use were more likely to register for the portal (48% vs. 11%; p < 0.01).

Conclusion Patients had positive perceptions of portals, and education increased portal use. Lack of email access is a notable barrier to electronic communication with vulnerable patients.
Laparoscopic Resection of Retroperitoneal Presacral Schwannoma: A Case Report
Authors: Ruoso Melina , Feranti Luiza , Andriguetto Paulo , Andriguetto Leonardo , Fidalski Solena , Aguiar Luiz
Published: December 2018

Retroperitoneal presacral schwannomas are uncommon and are usually diagnosed accidentally. We present here the case of a 23-year-old woman diagnosed with an expansive pelvic lesion during a routine gynecological examination. The precise location of the tumor, as well as its relation to adjacent structures, was determined through magnetic resonance imaging (MRI). The patient underwent laparoscopic lesion resection and the diagnosis was confirmed by immunohistochemistry. An MRI performed 2 months after surgery confirmed complete lesion resection.
Foramen Magnum Meningioma Presenting with Cough Syncope (Case Report and Review of the Literature)
Authors: Kaplan Metin , Hepgunsel Omer , Kok Selman , Gonen Murat
Published: December 2018

Foramen magnum meningiomas cause different symptoms based on the size and the location of the tumor. They often present with involvement of the long tracts and of the lower cranial nerves. Ataxia and occipitocervical headache are other common symptoms. In the present study, we report a case of foramen magnum meningioma presenting with cough syncope. A mass lesion located anterolateral to the foramen magnum was detected in a 38-year-old man during a magnetic resonance imaging (MRI) exam; the lesion extended from the inferior clivus to the level of the C2 vertebra. The neural axis has pushed towards posterior and contralateral side by the mass. We think that syncope occurred due to the encasement of the vertebral arteries by the tumor in addition to the compression of the neural axis. The posterolateral approach without condylar resection provides a safe surgical plane for total excision of these tumors. In our case, the tumor was totally removed and the syncope episodes were resolved.
Syndromale Formen der Adipositas
Authors: Vilser C. , Weihrauch-Blüher S.
Published: December 2018

Genetische Mechanismen der Adipositas sind komplex und umfassen das Zusammenspiel verschiedener genetischer Faktoren mit der Umwelt. Der Einfluss genetischer Faktoren wird dabei aktuell auf 40–70 % geschätzt. Es gibt jedoch auch verschiedene syndromale Adipositasformen, die sowohl monogen als auch oligogen auftreten können. Diese syndromalen Adipositasformen haben bisher maßgeblich zu unserem Verständnis molekularer Mechanismen des Energiehaushaltes und des Sättigungsverhaltens zur Kontrolle des Körpergewichts beigetragen. Es sind bisher mehr als 50 solcher Adipositas-Syndrome beschrieben. Meist bestehen weitere spezifische klinische Merkmale wie mentale Retardierung, Dysmorphien, Störungen endokriner Achsen oder organspezifische Entwicklungsstörungen, die oft ein typisches Präsentationsalter aufweisen. Bezüglich der assoziierten klinischen Symptome besteht im Hinblick auf Häufigkeit oder Ausprägungsgrad eine erhebliche Varianz. Die Adipositas tritt oft stammbetont auf und ist so gut wie nie ein isoliertes Merkmal. Eine aktuelle Übersicht über die häufigsten Adipositas-assoziierten Syndrome sowie zur differentialdiagnostischen Vorgehensweise ist nachfolgend dargestellt.
Metastabile Epiallele – beeinflussen epigenetische Varianten das individuelle Adipositasrisiko?
Authors: Krude H. , Kühnen P.
Published: December 2018

Epigenetische Modifikationen der DNA stellen einen sehr konservierten Regulationsmechanismus bei Pflanzen, Tieren und Menschen dar. Veränderungen beispielsweise der DNA Methylierung können zu der Entwicklung von Tumoren führen und spielen bei der Entstehung von sogenannten Imprinting Erkrankungen eine Rolle. Unklar ist jedoch die Bedeutung dieser Modifikationen für die Entstehung von chronischen Erkrankungen wie beispielsweise Adipositas. Gewebespezifität, genetischer Einfluss und Variabilität der DNA Methylierung stellen eine große Herausforderung für die Untersuchung dieser Zusammenhänge dar. Ergebisse aus epigenom-weiten Assoziationsstudien (EWAS) sowie die Identifikation von sogenannten metastabilen Epiallelen weisen jedoch darauf hin, dass es Unterschiede in der DNA Methylierung gibt, die das individuelle Risiko für die Entwicklung von Adipositas beeinflussen. Es werden zukünftige Studien zeigen, inwieweit Epigenetik im einzelnen von Bedeutung für die Adipositasentwicklung ist und ob dieses Wissen auch therapeutisch von Nutzen sein könnte.
Edge computing for space applications: Field programmable gate array-based implementation of multiscale probability distribution functions
Authors: Deak Norbert , Creţ Octavian , Echim Marius , Teodorescu Eliza , Negrea Cătălin , Văcariu Lucia , Munteanu Costel , Hângan Anca
Published: December 2018

Data processing is a challenging problem in space applications. The limited bandwidth available for communication between satellites and the ground and the increasing resolution of scientific instruments make it virtually impossible to transfer all the data recorded on board. Although various mitigation strategies were developed, large amounts of on-board data are still lost. This paper presents a Field Programmable Gate Array (FPGA)-based architecture which is able to perform on-board nonlinear analysis of data and compute probability distribution functions of fluctuations. We propose two implementations for our solution, which can be used for space applications and also other computational contexts. On a spacecraft, the logic resources of the FPGA will typically be shared by several designs running various digital signal processing algorithms. That is why each algorithm should be designed in variants, optimized for different criteria, so that the entire group of algorithms makes an efficient usage of the FPGA resources. The proposed solution focuses on two major optimization criteria, area and speed, such that the FPGA resources are efficiently used. Also, the power consumption is at least two orders of magnitude less in comparison with classical software implementations. The solution was tested with both synthetic and real data and shows excellent results paving the way towards an application that can be ported on a space-grade FPGA.
Realization of two-stage crossed beam cooling and the comparison with Delta-kick cooling in experiment
Authors: Luan Tian , Li Yufan , Zhang Xuesong , Chen Xuzong
Published: December 2018

We report the first experimental realization of the two-stage crossed beam cooling (TSCBC) method that we proposed in 2013 [L. Wang et al., J. Phys. B: At., Mol. Opt. Phys. 46, 195302 (2013)]. With the 87Rb Bose-Einstein condensation apparatus and electromagnet coils providing the magnetic levitation to counteract the gravitation, we simulated the micro-gravity environment and realized the TSCBC with 4 × 104 87Rb atoms. We estimated that the lowest temperature of atoms can be at 3.56 nK with a new method and verified that the cooling process is adiabatic enough with time-of-flight images. According to analysis, we believed that the noise of magnetic field was the main obstacle that hinders the further cooling of the atomic ensemble. Under the same experimental conditions, we carried out the Delta-kick cooling method and got a lowest temperature of 23.3 nK also with 4 × 104 87Rb atoms. According to the results of comparing experiments, we can see that the TSCBC method is more effective.
Second harmonic generation in strained transition metal dichalcogenide monolayers: MoS2, MoSe2, WS2, and WSe2
Authors: Mennel Lukas , Paur Matthias , Mueller Thomas
Published: December 2018

Second-harmonic generation (SHG) is a powerful measurement technique to analyze the symmetry properties of crystals. Mechanical strain can reduce the symmetry of a crystal and even weak strain can have a considerable impact on the SHG intensity along different polarization directions. The impact of strain on the SHG can be modeled with a second-order nonlinear photoelastic tensor. In this work, we determined the photoelastic tensors at a fundamental wavelength of 800 nm for four different transition metal dichalcogenide (TMD) monolayers: MoS2, MoSe2, WS2, and WSe2. Strain is applied using a three-point bending scheme, and the polarization-resolved SHG pattern is measured in backscattering geometry. Furthermore, we connected the strain dependent SHG with the strain dependence of the A-exciton energy. With the second-order nonlinear photoelastic tensor, full strain information can be accurately extracted from polarization-resolved SHG measurements. Accordingly, uniaxial strain, induced by polydimethylsiloxan (PDMS) exfoliation and transfer, is measured. We find that TMD monolayers fabricated with PDMS are strained by ∼0.2%. With the experimentally determined nonlinear photoelastic tensors, it will be possible to optically probe arbitrary strain fields in TMD monolayers.
Multi-pulse fitting of transition edge sensor signals from a near-infrared continuous-wave source
Authors: Lee Jianwei , Shen Lijiong , Cerè Alessandro , Gerrits Thomas , Lita Adriana E. , Nam Sae Woo , Kurtsiefer Christian
Published: December 2018

Transition-edge sensors (TESs) are photon-number resolving calorimetric spectrometers with near unit efficiency. Their recovery time, which is on the order of microseconds, limits the number resolving ability and timing accuracy in high photon-flux conditions. This is usually addressed by pulsing the light source or discarding overlapping signals, thereby limiting its applicability. We present an approach to assign detection times to overlapping detection events in the regime of low signal-to-noise ratio, as in the case of TES detection of near-infrared radiation. We use a two-level discriminator, inherently robust against noise, to coarsely locate pulses in time and timestamp individual photoevents by fitting to a heuristic model. As an example, we measure the second-order time correlation of a coherent source in a single spatial mode using a single TES detector.
Apparatus and method for efficient sampling of critical parameters demonstrated by monitoring an Overhauser geomagnetic sensor
Authors: Liu Huan , Dong Haobin , Ge Jian , Liu Zheng , Yuan Zhiwen , Zhu Jun , Zhang Haiyang
Published: December 2018

The polarization frequency of free radical solution in Overhauser geomagnetic sensor determines the quality of the Larmor precession signal generated by the sensor. To obtain the polarization frequency accurately, a test apparatus was designed in this paper, which can overcome existing problems in the presently used apparatuses, such as lower resolution, complex operation, etc. The proposed apparatus adopts a high-resolution direct digital synthesis as the controllable radio frequency (RF) signal source. Meanwhile, an analog-to-digital converter synchronization acquisition technology combined with a normalization approach is proposed, which effectively solves the problem of the uneven amplitude-frequency characteristic in the range of 50 MHz–100 MHz. Moreover, the apparatus is integrated by adopting the RF power and applying the weak signal amplifier as an auxiliary measurement channel. The equivalent circuit of the sensors resonant cavity was simulated, and the efficiency curve of the adjustable capacitors to the resonant frequency and the quality factor were obtained. The simulated results were further verified by testing the resonance cavity characteristics of a commercial Overhauser geomagnetic sensor under different conditions. Furthermore, the relationship between the polarization degree of the free radical solution and RF excitation power and time were also obtained. The testing methods and results were given, and the experimental data were analyzed. Finally, the experimental results demonstrate that the proposed apparatus can measure the polarization frequency of the free radical solution, the bandwidth, and the quality factor, accurately. Furthermore, it can be used for the determination of the polarization power and time during the design process for an Overhauser magnetometer.
Characterization of fast electron divergence and energy spectrum from modeling of angularly resolved bremsstrahlung measurements
Authors: Daykin T. S. , Sawada H. , Sentoku Y. , Beg F. N. , Chen H. , McLean H. S. , Link A. J. , Patel P. K. , Ping Y.
Published: December 2018

Characteristics of fast electrons generated in an intense laser-solid target interaction are studied by modeling angularly resolved bremsstrahlung measurements with a hybrid Particle-In-Cell code, Large Scale Plasmas. The experiment was performed using the 50 TW Leopard laser at the Nevada Terawatt Facility. A 100 μm thick Cu foil was irradiated by the 15 J, 0.35 ps laser at a peak laser intensity of 2 × 1019 W/cm2. Bremsstrahlung produced by transport and recirculation of the fast electrons in the foil was measured with two differential filter-stack x-ray spectrometers at 22° and 40° from the laser axis. The two-spectrometer signals simultaneously fit by varying single slope temperatures (Thot) and divergence angles (θ) enable for determining Thot and θ to be 1.1 ± 0.3 MeV and 15° ± 8°, respectively. The Thot inferred from the bremsstrahlung signals agrees with that from an escaped electron measurement, suggesting that that the bremsstrahlung is predominantly produced by the transport of the high energy fast electrons in the first pass.
Experimental and theoretical threshold photoelectron spectra of methylene
Authors: Coudert L. H. , Gans B. , Holzmeier F. , Loison J.-C. , Garcia G. A. , Alcaraz C. , Lopes A. , Röder A.
Published: December 2018

The threshold photoelectron spectrum of methylene (CH2), produced by consecutive H atom abstractions on methane, has been recorded using synchrotron radiation. The experimental spectrum spans the region of the X+ 2Πu ← X 3B1 ionizing transition. It is modeled starting from ab initio bending potentials and using the bending approach introduced by Coudert et al. [J. Chem. Phys. 148, 054302 (2018)] accounting for the quasilinearity of CH2 and the strong Renner-Teller interaction in CH2+. This first calculation yields a theoretical threshold photoelectron spectrum which is in moderate agreement with the experimental one. A more accurate approach treating the three vibrational modes is developed for computing the threshold photoelectron spectrum of triatomic C2v molecules. This new treatment is tested modeling the already measured threshold photoelectron spectrum of the X+ 2Πu ← X 1A1 ionizing transition of the water molecule. The threshold photoelectron spectrum of CH2 computed with the new approach compares more favorably with the experimental spectrum and yields an adiabatic ionization potential of 10.386(6) eV.
Bulk structural information from density functionals for patchy particles
Authors: Stopper Daniel , Hirschmann Frank , Oettel Martin , Roth Roland
Published: December 2018

We investigate bulk structural properties of tetravalent associating particles within the framework of classical density functional theory, building upon Wertheim’s thermodynamic perturbation theory. To this end, we calculate density profiles within an effective test-particle geometry and compare to radial distribution functions obtained from computer simulations. We demonstrate that a modified version of the functional proposed by Yu and Wu [J. Chem. Phys. 116, 7094 (2002)] based on fundamental measure theory for hard spheres produces accurate results, although the functional does not satisfy the exactly known low-density limit. In addition, at low temperatures where particles start to form an amorphous tetrahedral network, quantitative differences between simulations and theory emerge due to the absence of geometrical information regarding the patch arrangement in the latter. Indeed, here we find that the theory fits better to simulations of the floating-bond model [E. Zaccarelli et al., J. Chem. Phys. 127, 174501 (2007)], which exhibits a weaker tetrahedral order due to more flexible bonds between particles. We also demonstrate that another common density functional approach by Segura et al. [Mol. Phys. 90, 759 (1997)] fails to capture fundamental structural properties.
Heat transfer statistics in mixed quantum-classical systems
Authors: Liu Junjie , Hsieh Chang-Yu , Segal Dvira , Hanna Gabriel
Published: December 2018

The modelling of quantum heat transfer processes at the nanoscale is crucial for the development of energy harvesting and molecular electronic devices. Herein, we adopt a mixed quantum-classical description of a device, in which the open subsystem of interest is treated quantum mechanically and the surrounding heat baths are treated in a classical-like fashion. By introducing such a mixed quantum-classical description of the composite system, one is able to study the heat transfer between the subsystem and bath from a closed system point of view, thereby avoiding simplifying assumptions related to the bath time scale and subsystem-bath coupling strength. In particular, we adopt the full counting statistics approach to derive a general expression for the moment generating function of heat in systems whose dynamics are described by the quantum-classical Liouville equation (QCLE). From this expression, one can deduce expressions for the dynamics of the average heat and heat current, which may be evaluated using numerical simulations. Due to the approximate nature of the QCLE, we also find that the steady state fluctuation symmetry holds up to order ℏ for systems whose subsystem-bath couplings and baths go beyond bilinear and harmonic, respectively. To demonstrate the approach, we consider the nonequilibrium spin boson model and simulate its time-dependent average heat and heat current under various conditions.