bluuebunny/crossref_metadata_2025 huggingface dataset:
Test Analysis Of The Development Conversion And Recognition Prior Learning Models On Vocational Teachers’ Education
Authors:   Vocational Education S3 Doctoral Program, Yogyakarta State University Yogyakarta, Indonesia, Abdillah Fuad , PH Slamet ,   Faculty of Engineering, Yogyakarta State University,Yogyakarta, Indonesia, Sukardi  ,   Faculty of Engineering, Yogyakarta State University, Yogyakarta, Indonesia
Published: September 2019

This study aims to: (1) develop a conversion and recognition of prior learning (RPL) model on the vocational teachers’ education in the field of automotive engineering: (2) determine the software quality developed by the functional suitability, efficiency of performance, compatibility, usability, reliability aspects, maintainability, portability, and security testing based on ISO 25010. The method applied in this Research and Development (R & D) is the Brogg and Gall. The results of the study revealed that: (1) the conversion and prior learning recognition (RPL) models on vocational teachers’ education were in accordance with the requirements of the field (2) Test results on the functional suitability scored 10.5 and a mean of 3.45; the efficiency of performance had a score of 9.5 and a mean of 3.15; compatibility scored 8 with a mean of 4; the usability had a score of 19.5 and mean of 3.2; while the reliability aspect had a score of 13.5 and a mean score of 3,37. Furthermore, the conversion and prior learning recognition models are flexible in use and competent. Regarding the portability aspect, it is compatible with Mozilla Firefox, Google Chrome, and Internet Explorer browsers. It is free from XSS and SQL injection vulnerabilities seen from the security information system.
Multiplexers, Demultiplexers, Current Progress And Algorithms Of Wavelength Assignment In WDM Network
Authors:   Assist. Prof, Department of ECE, Siddhartha Institute of Technology & Sciences, Narapally, Ghatkesar, Hyderabad, Telangana, India, Prakash Immidisetty V , Vijayabhasker Valiki ,   Assist. Prof, Department of ECE, Siddhartha Institute of Technology & Sciences, Narapally, Ghatkesar, Hyderabad, Telangana, India, Gadari Srinivas ,   Assist. Prof, Department of ECE, Siddhartha Institute of Technology & Sciences, Narapally, Ghatkesar, Hyderabad, Telangana, India.
Published: September 2019

The backbone of modern telecommunication industry comprises of wavelength division multiplexed (WDM) framework. It is imagined that our reality will turn out to be progressively interconnected with mobile communications empowering us to play out an expanding scope of tasks. Future wireless networks will require optical network antenna base examinations with adequate data transmission to give singular clients a bigger transfer speed. It is normal that high capacity networks will utilize Wavelength Division Multiplexing (WDM) to build the complete transfer speed transmitted over the optical access network. A WDM framework transmits data by multiplexing number of free data conveying wavelengths on a single fiber and de-multiplexing at the receiver. The paper describes the Multiplexers, De-multiplexers, current progress of WDM and the algorithms of wavelength in WDM network. WDM includes transmission of no. of signs having distinctive wavelengths in parallel on a single optical fiber. Wavelength Division Multiplexed switching networks are critical for the future transport networks
Design Of Its Through IoT
Authors:   Department of Electronics and Communication Engineering, Siddhartha Institute of Technology & Sciences, Hyderabad, Telangana, India, Velmani R. , Reddy A. Srinivasa ,   Department of Electronics and Communication Engineering, Siddhartha Institute of Technology & Sciences, Hyderabad, Telangana, India., Reddy M. Ranjith ,   Department of Electronics and Communication Engineering, Siddhartha Institute of Technology & Sciences, Hyderabad, Telangana, India
Published: September 2019

Due to the population and economic growth, the vehicle population is increased in India and that creates a critical burden on traffic management in metropolitan cities (Hyderabad, Bangalore, Chennai, Mumbai, etc.) and towns of the country. This paper proposes Intelligent Transportation System (ITS) by using information and communication technologies like IoT and data analytics and that apply to transport operations. ITS aimed to create safe, efficient, reliable and environmentally sustainable smart transport systems. At every traffic signal the density of the traffic is detected with the help of IR sensors, then the traffic level is obtained. The IR sensors are connected to 8051 microcontroller. A mobile data service is connected to microcontroller to deliver the real time traffic information through IoT to the traveller, so that he can know the traffic level and can take an alternate. The information gathered from the traffic signals is processed with the help of Big Data Analytics and the data is to be sent to every traveller’s to make their journey safe and reach their destination in time.
Comparative Study on Seismic Responses of Multistorey Building Frame with Infills using Linear and Nonlinear Analysis
Authors:   Assistant Professor, Department of Civil Engineering, Siddhartha Institute of Technology and Sciences, Hyderabad, Telangana, India, Swapna S. , Venkatesh T. ,   Assistant Professor, Department of Civil Engineering, Siddhartha Institute of Technology and Sciences, Hyderabad, Telangana, India., Kavitha V. ,   Assistant Professor, Department of Civil Engineering, Siddhartha Institute of Technology and Sciences, Hyderabad, Telangana, India., Kumar K.Sanjay ,   Assistant Professor, Department of Civil Engineering, Siddhartha Institute of Technology and Sciences, Hyderabad, Telangana, India
Published: September 2019

In coming up with of RCC frames typically the result of infill walls is neglected however this wall contributes to the rigidity and firmness of the structure. within the gift study we'll compare the unstable responses of a building by coming up with a infill wall with the assistance of equivalent diagonal strut methodology victimisation linear and non linear analysis additionally victimisation E-tabs code
Pelatihan Komputer Dasar Bagi Kader PKK dan Posyandu Di Desa Patikraja
Authors: Wanti Linda Perdana , Tripustikasari Eka
Published: September 2019

Empowerment of Family Welfare or often abbreviated as PKK is a movement that has been built from the center to the village and its existence and benefits have been felt by the community. This PKK activity is reflected in the 10 PKK Principal Programs, one of which is focused on health and attention specifically aimed at maternal and child health. So that an Integrated Service Post (Posyandu) was formed consisting of trained Posyandu cadres. These trained Posyandu cadres are not only seen from the way they handle maternal and child health but also must be supported by their ability to use computers in the process of recording and data collection. However, not all PKK and Posyandu Cadres, especially in villages, are adept at using computers, for example, PKK Cadres and Patikraja Village Posyandu. In fact, many cadres are new to computers and cannot use standard programs such as Microsoft PowerPoint and Microsoft Word. The goal of this community service program is to improve the capabilities and competencies of PKK Cadres and Patikraja Village Posyandu in operating computers to support good and smooth performance in terms of administration and data collection. Based on the results of the evaluation it was seen that PKK cadres and the Patikraja Village Posyandu attended the training with great enthusiasm and they were able to practice the material very well.
Therapy Management of Metastatic Prostate Carcinoma in General Practice
Authors: Meisel Alexander
Published: September 2019

ABSTRACT
In general, advanced prostate cancer is initially treated with androgen deprivation therapy (ADT). Despite high response rates to this treatment, the response is not durable and most of the patients eventually develop metastatic castration-resistant prostate cancer (mCRPC). The treatment strategies for mCRPC usually include a combination of different approaches, such as hormone therapy, chemotherapy, or radiation. Here, we discuss the case of a 78-year old patient with advanced prostate cancer who developed mCRPC after 4 years of continuous therapy with ADT. The patient was subsequently treated with analgesic radiotherapy, followed by chemotherapy, including docetaxel and cabazitaxel. The patient responded well to the treatment, with acceptable treatment-related toxicity. Three years later, however, the disease progressed, and the patient received anti-hormonal therapy with enzalutamide. In conclusion, this case report discusses the different therapy selections and outcomes. Finally, a literature overview offers a comprehensive insight into the current systemic therapies for mCRPC.
CD19-Directed CAR T Cells Treatment in a Patient With Refractory DLBCL and CNS Involvement
Authors: Ring Alexander , Müller Antonia Maria
Published: September 2019

ABSTRACT
Introduction: Diffuse large B-cell lymphoma (DLBCL) is the most common neoplasm of the lymphatic system. Treatment and clinical management are difficult in the relapsed/refractory (R/R) setting. Chimeric antigen receptor (CAR) T cells are genetically engineered using autologous patient lymphocytes and have shown very promising results in the treatment of relapsed and refractory cases of DLBCL.

Methods: A 64-year-old male patient with refractory DLBCL and central nervous system (CNS) involvement after 9 lines of therapy was treated with CD19-specific CAR T cell therapy at the Department of medical oncology and hematology at the University Hospital of Zurich and followed-up for 10 weeks.

Results: Autologous lymphocytes were successfully harvested and transfected/expanded for CAR T cell production. Conditioning chemotherapy and CAR T infusion was well tolerated. Post-infusion side effects were mild (cytokine release syndrome [CRS] grade 1−2), with limited signs of neurotoxicity. Ten weeks after CAR T cell therapy, an excellent response could be documented via PET-CT. The CNS lesion disappeared as assessed via cranial MRI.

Conclusion: CD19-targeted CAR T cell therapy is a revolutionary treatment option for heavily pre-treated R/R DLBCL even in the setting of CNS involvement.
Esofagitis inducida por tetraciclinas
Authors: Royero-Gutiérrez Henry Alberto , Ahumada-Rodríguez Wendy Paola
Published: September 2019

Masculino de 16 años, consultó por dolor torácico retroesternal de 72 horas de evolución, exacerbado por ingesta de alimentos. El dolor fue gradual hasta percibirlo con intensidad de 9/10, se irradiaba a espalda y hombro derecho. Ingería Doxiciclina para el acné, acostándose la mayoría de las veces después de consumirlas. Se indicó endoscopia digestiva alta (EVDA), observándose lesiones ulceradas en tercio medio esofágico, con mucosa adyacente respetada (ver figura 1 y 2); se inició Acetaminofen más Tramadol como analgésico. Quince días después curso asintomático y la EVDA encontró el esófago sano (ver figura 3). El diagnóstico de esofagitis inducida por medicamentos puede ser hecho por la historia clínica, la EVDA debe indicarse en pacientes que presentan síntomas severos, signos de alarma o persistencia de éstos una semana después de suspender el medicamento. En la mayoría de casos la esofagitis por tetraciclinas mejora en pocos días sin ninguna intervención (1,2).
Pengaruh Fungsionalitas dan Likeability Jalur LRT Terhadap Citra Kawasan Kelapa Gading
Authors: Saputra Eka , Hartanti Nurhikmah Budi
Published: September 2019

Perkembangan jalur LRT di kawasan Kelapa Gading merupakan alternatif solusi terhadap pergerakan dan aktifitas yang semakin meningkat. Perkembangan suatu elemen baru akan berdampak pada perubahan kondisi visual suatu kawasan, yang selanjutnya akan mempengaruhi image yang terbentuk di masyarakat terhadap kawasan tersebut. Oleh karena itu dilakukan studi mengenai potensi perubahan citra kawasan Kelapa Gading dengan adanya jalur LRT sebagai elemen kawasan yang baru. Penelitian ini dilakukan dengan pendekatan mix methods untuk mengetahui sejauh mana potensi perubahan yang terjadi terhadap citra kawasan Kelapa Gading yang sudah terbentuk dengan kehadiran elemen baru yaitu jalur LRT. Fokus penelitian ini adalah pada aspek fungsional dan likeability terhadap elemen jalur LRT. Temuan yang diperoleh adalah bahwa potensi perubahan citra kawasan Kelapa Gading sangat terkait dengan aspek fungsional dan likability terhadap jalur LRT, sehingga apabila likability terhadap keberadaan jalur LRT kuat dan secara fungsional bernilai positif bagi masyarakat, maka elemen tersebut dapat merubah citra kawasan Kelapa Gading.Kata Kunci: Perubahan citra kawasan, elemen baru LRT, aspek likeability, aspek fungsional
The optimum tilt angle and orientation for Solar panels
Authors: Mohammed Eman
Published: September 2019

In this paper we present evaluated the performance of four small PV modules at different tilt angle and analyze the relationship of solar radiation power Production with the angle by using actual measurement data for all months of the year and in August specially. And then study the relationship between the solar radiation and output power. We installed these panels in four angles at 0°, 15°, 30°, 45°, and fixed solar panel all the month of the year and fixed in august especially to study the daily solar radiation in summer .The results indicate that the highest output power of the PV is obtain in July at the 35° tilt surface for all day’s year.
Hubungan Pengetahuan dengan Perilaku Kesehatannya pada Orangtua Anak dengan Penyakit Jantung Bawaan
Authors: Rahmi Nisa Alifia , Soetadji Anindita
Published: September 2019

Latar belakang : Setiap tahun di Indonesia diperkirakan akan lahir 40.000 bayi dengan Penyakit Jantung Bawaan (PJB). Jumlah tindakan bedah dan intervensi non bedah yang dilakukan pada anak PJB menunjukkan kenaikan, namun angka kematian masih tetap tinggi. Orangtua sebagai bagian yang paling dekat dengan anak diharapkan mempunyai pengetahuan yang cukup serta sikap yang mendukung sehingga akan terbentuk perilaku kesehatan yang menunjang perawatan anak dengan PJB. Tujuan penelitian ini adalah untuk mengetahui hubungan antara pengetahuan dan perilaku orangtua terhadap anak dengan penyakit jantung bawaan

Metode : Penelitian observasional dengan pendekatan cross sectional. Subyek penelitian adalah orangtua yang mempunyai anak dengan PJB yang datang ke Poliklinik RSUP Dr. Kariadi Semarang bulan Maret–Juni 2010. Pengambilan data dilakukan dengan pengisian kuesioner terpimpin yang telah diujicobakan. Data dianalisis dengan uji korelasi Spearman menggunakan SPSS ver 15 for Windows dengan nilai p<0,05.

Hasil : Jumlah responden pada penelitian ini sebanyak 30, terbanyak usia 31–40 tahun (53,33%). Pendidikan terbanyak SD (37%), pekerjaan ibu terbanyak adalah ibu rumah tangga (83%). Sumber biaya kesehatan yang banyak digunakan adalah asuransi (jamkesmas dan jamsostek) sebesar 93%. Sebanyak 86,7% responden mempunyai tingkat pengetahuan sedang dan 76,7% responden berperilaku baik. Tidak ada hubungan bermakna antara pengetahuan dengan perilaku orangtua terhadap anak dengan PJB, didapatkan r=0,216.

Simpulan : Pengetahuan tidak berhubungan bermakna dengan perilaku orangtua terhadap anak dengan PJB. Ada faktor-faktor lain yang lebih mempengaruhi perilaku orangtua sehingga diperlukan penelitian lebih lanjut mengenai faktor-faktor ini.

Kata kunci : Pengetahuan, perilaku, penyakit jantung bawaan
Real-time Tools in Classroom
Authors: Bakonyi Viktória , Illés Zoltán , Illés Zoltán
Published: September 2019

Today we are surrounded by IT devices and a lot of different applications from which more and more are usually work in real-time. These systems are mainly embedded systems but there are general operating systems which offers such possibilities too. Moreover, we can talk about real-time applications on the web as well. Therefore, it became very important for each informatician especially for future informatics teachers to know about the bases of this technology. Everybody knows the fact that each new technology appears sooner or later in education and finds its place in it. These new possibilities may give additional tools into teachers’ hands. The question is whether they can live with the opportunity or not.
PENGARUH E-SERVICE QUALITY TERHADAP PURCHASE INTENTION DENGAN E-WOM DAN PERCEIVED VALUE SEBAGAI VARIABEL INTERVENING
Authors: Wicaksono Ibnu Abdullah , Darmo Ika Suhartanti
Published: September 2019

Penelitian ini bertujuan untuk mengetahui pengaruh dari e-service quality terhadap purchase intention dengan e-word of mouth dan perceived value sebagai variabel intervening. Penelitian ini merupakan penelitian kuantitatif dengan jumlah sampel sebanyak 134 responden yang merupakan pengguna OLX.co.id yang sudah pernah melakukan pembelian melalui website OLX.co.id sampel ditentukan menggunakan teknik nonprobability purposive sampling. Hasil dari perhitungan SPSS memperlihatkan bahwa 5 hipotesis yang terdapat dalam penelitian ini diterima, yakni e-service quality mempengaruhi secara signifikan variabel e-word of mouth, eservice quality mempengaruhi secara signifikan variabel perceived value, E-word of mouth mempengaruhi secara signifikan variabel purchase intention, perceived value mempengaruhi secara signifkan variabel purchase intention, dan terakhir e-service quality berpengaruh terhadap purchase intention
PENGEMBANGAN USAHA RUMAHAN PEMBUAT ROTI MANIS ANGGOTA KOMUNITAS MEMASAK CHEF DEPOK
Authors: Wulandari Endang , Rahmawati Rahmawati
Published: September 2019

Komunitas memasak Chef Depok adalah kelompok wanita yang ingin meningkatkan kemampuan dan wawasan dalam bidang kuliner, dan ingin mendapatkan penghasilan tambahan dengan membuat berbagai masakan terutama roti manis. Kelompok ini masih memiliki masalah. Mitra belum bisa menentukan harga pokok produk dengan benar, belum mempunyai pembukuan, dan kondisi produk yang tidak konsisten. Pengembangan usaha rumahan pembuat roti manis anggota komunitas memasak Chef Depok telah dilakukan. Tujuan kegiatan ini adalah: 1) Perbaikan dan pendampingan manajemen usaha; dan 2) Standarisasi proses pembuatan roti manis sehingga produk yang dihasilkan konsisten dan sesuai dengan yang diinginkan. Tim abdimas bertindak sebagai fasilitator dan telah melakukan pendampingan untuk menentukan harga pokok produk dan pembukuan sederhana. Selain itu mitra telah mengetahui cara produksi pangan yang baik, standarisasi resep, dan penerapan higiene dan sanitasi yang baik sehingga dihasilkan produk roti manis yang konsisten. Pengetahuan dan kemampuan mitra terhadap materi yang diberikan meningkat rata-rata sebesar 57.75%
us 2019 190 IMPLEMENTASI PROGRAM KESEHATAN REPRODUKSI REMAJA DI PUSKESMAS BANCAK KABUPATEN SEMARANG
Authors: Messakh Sanfia Tesabela
Published: September 2019

Masa muda atau remaja adalah masa dimana pertumbuhan dan perkembangan berjalan dengan cepat
baik secara fisik maupun intelektual dikaitkan dengan mulai terjadinya pubertas. Oleh sebab itu masa
ini adalah masa transisi anak-anak menuju kedewasaan dengan demikian permasalahan kesehatan
reproduksi yang dihadapi remaja terus mengalami peningkatan. Oleh sebab itu kurangnya informasi
mengenai kesehatan reproduksi remaja dapat berdampak negatif pada perilaku menyimpang seperti
hubungan seksual diluar nikah, kehamilan yang tidak diinginkan yang berdampak bagi remaja untuk
melakukan tindakan aborsi, pernikahan dini serta terinfeksi penyakit menular contohnya HIV/AIDS.
Sebagai langkah awal mencegah terjadinya dampak-dampak negatif, maka pendidikan kesehatan
reproduksi bagi remaja sangat penting. Pusat Kesehatan Masyarakat (Puskesmas) sebagai layanan
kesehatan primer memiliki tanggung jawab untuk melakukan pembekalan pengetahuan bagi
remaja.Tujuan penelitian ini untuk mengetahui apakah implementasi program kesehatan reproduksi
remaja di Puskesmas Bancak sudah terlaksana dengan maksimal. penelitian saat ini metode yang
digunakan adalah kualitatif – deskritif agar mendapatkan data mendalam serta mengandung makna.
Teknik yang digunakan untuk pengumpulan data di lakukan dengan wawancara secara mendalam.
Subjek penelitian yaitu kepala Puskesmas dan pengelola program kesehatan remaja. Tempat penelitian
di Pukesmas Bancak. Berdasarkan penelitian yang telah dilakukan di Puskesmas Bancak terdapat 3
tema yang diperoleh yaitu pelayanan kesehatan remaja, jejaring program kesehatan peduli remaja dan
hambatan dalam memberikan pelayanan kesehatan kepada remaja.
EVALUASI SEDIAAN PATCH DAUN HANDEULEUM (Graptophyllum griff L) SEBAGAI PENURUN PANAS
Authors: Hermanto Fauzi Juniawan , Nurviana Vera
Published: September 2019

Daun handeuleum digunakan secara empiris oleh masyarakat Cibalong sebagai obat penurun
panas. Kandungan flavonoid dalam daun handeuleum dapat bekerja sebagai inhibitor cyclooxygenase
(COX) yang memicu pembentukan prostaglandin yang berperan dalam proses inflamasi dan
peningkatan suhu tubuh. Penelitian ini dilakukan untuk memanfaatkan aktivitas antipiretik dengan
membuat sediaan patch transdermal daun handeuleum sehingga diperoleh suatu sediaan yang efektif
dan efisien dalam penggunaannya. Proses pembuatan sediaan dibagi menjadi 3 formulasi dengan
perbandingan konsentrasi ekstrak daun handeuleum secara berturut-turut yaitu formula 1 (0,2 g),
formula 2 (0,6 g), dan formula 3 (1 g). Dosis 2 diperoleh berdasarakan konversi dari dosis empirisnya.
Evaluasi sediaan dilakukan untuk mengetahui formula yang memiliki kualitas patch daun handeueleum
yang paling baik. Evaluasi ini mencakup pengamatan organoleptik, uji keseragaman bobot, uji
ketahanan lipat, uji ketebalan, uji pH, dan uji daya serap kelembaban. Hasil evaluasi sediaan pach
transdermal daun handeuleum menunjukkan bahwa semua formula memenuhi persyaratan mutu
sediaan.
OLA KONSUMSI MAKANAN PADA ANAK AUTISME
Authors: Rukmasari Erna Arum
Published: September 2019

Saat ini prevalensi anak autisme meningkat dari tahun ke tahun. Tahun 1987 jumlah anak autisme
diperkirakan 1:5000. Jumlah ini meningkat dengan pesat, pada tahun 2005 menjadi 1:160, dan tahun
2014 WHO mengidentifikasi 1 dari 68 anak mengalami autisme (1 dari 42 anak laki-laki dan 1 dari
189 anak perempuan). Kondisi yang sering terjadi pada anak autisme adalah gangguan pencernaan dan
penyimpangan metabolisme yang menyebabkan gluten dan kasein tidak bisa dicerna dan berubah
menjadi peptida yang bisa meracuni otak dan memberi efek pada gangguan fungsi otak, sehingga anak
menjadi hiperaktif. Terapi diit merupakan salah satu terapi yang dapat dilakukan di rumah dengan cara
menghindari berbagai jenis makanan yang mengandung gluten, kasein, jamur, dan makanan yang
mengandung zat aditif, sehingga pengaturan pola makan perlu mendapat perhatian. Penelitian ini
bertujuan untuk mengetahui pola konsumsi makanan pada anak autisme di SLBN 1 Garut. Penelitian
ini menggunakan rancangan crossectional dengan sampel penelitian total populasi yaitu seluruh siswa
SLBN 1 Garut penyandang autisme. Pola konsumsi makanan dikumpulkan dengan metode food recall
dan food frekwensi yang diolah dengan program NutriSurvey dan dianalisis secara deskriptif. Hasil
penelitian menunjukkan rata-rata asupan energi sebanyak 1673,863 Kcal, asupan protein 63,113 gram,
asupan lemak 61,100 gram, dan asupan karbohidrat sebanyak 255,250 gram. Sepuluh jenis makanan
yang paling banyak dikonsumsi anak autisme di SLB N 1 Garut adalah susu, es krim, nugget, sosis,
biskuit, mie instan, roti, keju, youghurt, dan jus buah. Hasil penelitian dapat disimpulkan bahwa anak
autisme di SLB Negri 1 Garut memiliki rata-rata asupan protein, lemak dan karbohidrat di bawah
kebutuhan yang seharusnya, dan mengkonsumsi makanan yang mengandung gluten, kasein dan
jamur/fermentasi.
Disarankan orang tua untuk meningkatkan pemberian nutrisi dan membatasi pemberian makanan yang
mengandung gluten, kasein dan mengandung zat aditif, serta menggantinya dengan makanan yang
lebih sehat.
Antibacterial activity of Sargassum cristaefolium and Dictyota cervicornis against to bacteria
Authors: Pouladi Saide
Published: September 2019

ABSTRACTBACKGROUND Nowadays the treat infection of bacterial diseases faced limitations because of the harm of industrial artificial antibiotics for the digestive system and immune system. Consequently, the scientists seek to replace conventional anti-biotics whit natural ones.AIM OF STUDY The central thesis of this study is to identify potential antimicrobial properties of the Sargassum cristaefolium and Dictyota cervicornis extracts.MATERIAL AND METHOD Water-methanol, n-hexane, Ethyl acetat, methanol and water extracts of two marine macroalgae from chahbahar bay (Iran) were weighed up in terms of antimicrobial activity by Agar disk diffusion, MIC and MBC methods against (L.monocytogens as gram-positive bacteri, and (E.coli and P. aeruginosa as gram-negative bacteria).RESULTS According to the obtained results, the hot water extract in S. cristaefolium and D.cervicornis none of the strains examined is of antibiotic effects. Ethyl acetat extract in comparison with other extracts displayed better antibacterial activity (P<0.05). Highest zone of inhibition (14 mm) was recorded for Ethyl acetat extract of S. cristaefolium contrary to L. monocytogenes. Maceration method extracts did not display any effect towards the studied bacteria.CONCLUSION For extracting antimicrobial compounds, the ultrasound method was a successful method.
ANTIBACTERIAL ACTIVITY OF ETHANOL CRUDE EXTRACTS OF WHOLE PLANT OF THE UGANDAN PHYLLANTHUS AMARUS SCHUMACH. & THONN AGAINST SHIGELLA DYSENTERIAE
Authors: Arthur Magimbi , Aliero Adamu Almustapha , Odda John
Published: September 2019

Apart from being used for the treatment of malaria fevers, mono-herbal preparation of Ugandan Phyllanthus amarus is widely by local communities in central Uganda, for treatment of bacterial dysentery.  However, efficacy studies regarding the mono-herbal extracts of the Ugandan Phyllanthus amarus against Shigella dysenteriae is lacking. The present study was aimed at determined the antibacterial activity of aqueous ethanol crude extracts of whole plant of Phyllanthus amarus against Shigella dysenteriae. Whole plant of Phyllanthus amarus was collected from Wakiso district central of Uganda. Different concentrations (128µg/ml, 256µg/mL-1 and 512µg/ mL-1) of the ethanol crude extract of whole plant of Phyllanthus amarus were tested against Shigella dysenteriae using agar well diffusion method. Minimum inhibitory concentration (MIC) was determined using broth tube dilution method while Minimum bactericidal concentration (MBC) was determined by culture method. The results of this study showed that, Shigella dysenteriae was sensitive to different concentrations (128µg/ mL-1, 256µg/ mL-1and 512µg/ mL-1) of ethanol crude extract of whole plant of Phyllanthus amarus possessed antibacterial against Shigella dysenteriae with mean and standard error mean zone of inhibition ranging from 11.5±0.5 to 13.5±0.5mm, while the positive control had mean and standard error mean zone of inhibition 24.5±0.5mm. The MIC and MBC of the ethanol crude extract of whole plant of Phyllanthus amarus against Shigella dysenteriae was found to be 32µg/ml and 64µg/ml respectively. This study found that the whole plant of phyllanthus amarus of ethanol crude extract was active against Shigella dysenterie.  Further study should be carried out test whole plant Phyllanthus amarus crude extract on different microorganisms that cause dysentery to find out its activity against them and spectrum, determine lead compound in the whole plant Phyllanthus amarus crude extract responsible for the anti-microbial activity against Shigella dysenteriae and also determine the mechanism of action by which this plant crude extract inhibits Shigella dysenteriae.
OCCURRENCE OF Yersinia enterocolitica SEROTYPE O:9, AND Citrobacter freundii, TWO POTENTIAL HUMAN PATHOGENS IN THE THROATS OF TROPICAL PIGS OF GRENADA ORIGIN
Authors: Amadi Victor Anozie , Hariharan Harry , Matthew-Belmar Vanessa , Nicholas-Thomas Roxanne , DeAllie Claude , Sharma Ravindra
Published: September 2019

A study to determine the occurrence of Yersinia enterocolitica and Citrobacter freundii, two potential human pathogens in the throats of tropical pigs of Grenada origin and the antimicrobial pattern of the isolates was carried out. During a period of 30 days (15 September 2017 to 15 October 2017), throat swabs from a total of 97 weaned pigs were sampled to isolate and characterize Y. enterocolitica by serotyping and resistance testing, and to isolates C. freundii. Of the pigs tested, four (4.1%) pigs were positive for Y. enterocolitica. The four Yersinia-positive pigs included one (2.4%) of 41 male pigs and three (5.4%) of 56 female pigs. There were no significant differences between the proportions of Yersinia-positive male and female pigs (p = 0.8437). Of these four Yersinia-positive pigs, two were mixed with C. freundii, one had slight contamination, and the other was pure. All belonged to serotype 0:9.  There were 31 pigs positive for C. freundii, and all showed mixed growth. Antimicrobial susceptibility tests against 14 drugs indicated that all isolates of Y. enterocolitica were susceptible to third-generation cephalosporins and fluoroquinolones, two classes of antimicrobials recommended for the treatment of Y. enterocolitica infection in humans.
Testing heavy metals biomonitoring through birds of prey as top predators
Authors: Cumbo Valentina , Galluzzo Francesco , Cammilleri Gaetano , Vella Antonio , Macaluso Andrea , Rizzuto Ilaria , Pisano Antonino , Ferrrantelli Vincenzo , Seminara Salvatore
Published: September 2019

The Experimental Zooprophyilactic Institute of Sicily has great opportunities and validated methods (accreditated by the national control unit ACCREDIA) for biodiversity monitoring and analysis of fauna samples. The fauna recovery centers of Bosco di Ficuzza (Palermo) and Colli San Rizzo (Messina) routinely send dead specimens to the Institute to perform every category of analysis for both medical and veterinary purpose. Measuring heavy metals concentrations in top predators is a strong indicator for territory and biodiversity health monitoring to take management and conservation actions for natural systems. In this study, two specimens of the Common buzzard (Buteo buteo L., Accipitridae) were investigated for Cd, Fe and Pb content by an Inductively Coupled Plasma Mass Spectrometry (ICP-MS) method. Results show that in one sample only Pb levels exceed cut-off values in organs like the liver, kidney and muscle with a concentration of 0,005 mg/Kg. This is probably a cause of prey ingestion killed by lead pellets. In the other sample the only high level was for Fe with a concentration of 0,386 mg/Kg. According to literature (Scheuhammer 1987), Pb present in plumage is probably a reflection of external pollution and it not depends on diet, while its high concentration in internal organs is directly related to ingestion of lead pellets during consumption of preys killed by them.
Improving Participants' Experience in the Online Survey Process
Authors: Billingsley Luanne , Riddle Kristie
Published: September 2019

Health care professionals frequently participate in surveys. Increased technology supports low-budget online surveys as a common method for collecting information. Decreased interaction with the surveyor, a lack of trust in the survey process, and time constraints often reduce response rates. Improved communication and shared results can positively influence the participants' experience.

[
J Contin Educ Nurs.
2019;50(10):439–441].
QSEN Safety Competency: The Key Ingredient Is Just Culture
Authors: Armstrong Gail
Published: September 2019

Patient safety is a familiar and long-standing competency for nurses. Effective error gap analysis is necessary to improving patient safety. Recent updates in patient safety emphasize just culture as vital to improving patient safety. This article explores how just culture has expanded the understanding of patient safety and offers some take-away tips for nurses.

[
J Contin Educ Nurs.
2019;50(10):444–447.]
The Flipped Classroom Format and Nursing Professional Development
Authors: Pilcher Jobeth
Published: September 2019

The flipped classroom is increasingly described in the education literature. In the most basic terms, the phrase
flipped classroom
refers to learners doing some type of preparatory work prior to attending a class. Class time is then spent applying the content. This article includes an overview of evidence related to the flipped classroom, as well as examples of how the flipped format has been used in nursing professional development. Hints are included regarding planning and implementing a flipped classroom.

[
J Contin Educ Nurs.
2019;50(10):449–454.]
Visual and Refractive Outcomes of LASIK With the SCHWIND ESIRIS and WaveLight ALLEGRETTO WAVE Eye-Q Excimer Lasers: A Prospective, Contralateral Study
Authors: Mearza Ali A. , Muhtaseb Mohammed , Aslanides Ioannis M.
Published: September 2019

Purpose

To compare the safety, efficacy, and predictability of LASIK with the SCHWIND ESIRIS and WaveLight ALLEGRETTO WAVE Eye-Q excimer laser platforms.

Methods

This prospective study comprised 44 eyes of 22 consecutive patients who were treated with LASIK using the Moria M2 microkeratome. One eye was treated with the SCHWIND ESIRIS laser and the fellow eye treated with the WaveLight ALLEGRETTO WAVE Eye-Q laser. All eyes operated with the SCHWIND ESIRIS were treated with standard aspheric ablation, whereas the eyes operated with the WaveLight ALLEGRETTO WAVE Eye-Q received treatment with three different ablation types according to the common practice at our clinic. Outcome measures were uncorrected visual acuity (UCVA), best spectacle-corrected visual acuity (BSCVA), manifest refraction, and proximity to target refraction at 6-month follow-up.

Results

At 6 months postoperative, mean decimal UCVA was 0.96±0.22 (range: 0.3 to 1.2) for ESIRIS eyes and 0.98±0.17 (range: 0.6 to 1.2) for ALLEGRETTO eyes (
P
=.57). Mean postoperative spherical equivalent refraction was −0.02±0.28 diopters (D) (range: −0.75 to +0.75 D) for ESIRIS eyes and 0.11±0.91 D (range: ±1.00 to ±3.88 D) for ALLEGRETTO eyes (
P
=.49). Of the ESIRIS eyes, 20/22 (91%) were within ±1.00 D of target refraction and 20/22 (91%) were within ±0.50 D of target refraction. Of the ALLEGRETTO eyes, 20/22 (91%) and 19/22 (86%) were within ±1.00 D and ±0.50 D, respectively, of target refraction. No patient lost ⩾2 lines of BSCVA in either group.

Conclusions

No differences were seen in safety and efficacy outcome parameters between the SCHWIND ESIRIS and WaveLight ALLEGRETTO WAVE Eye-Q excimer lasers when used according to a previously established treatment algorithm at our clinic in the treatment of refractive error. [
J Refract Surg.
2008;24:885–890.]
Estimation of Posterior Corneal Power for IOL Calculation After Myopic LASIK
Authors: Srivannaboon Sabong , Rakpanichmanee Thanapat , Cheng Arthur C.K. , Fam Han-Bor
Published: September 2019

Purpose

To estimate the posterior corneal power for intraocular lens (IOL) calculation after myopic LASIK.

Methods

A retrospective study of 50 patients (92 eyes) who underwent uneventful myopic LASIK was conducted. Pre- and postoperative data (12 months) were collected including refraction and Orbscan II (Bausch & Lomb) for simulated keratometry (Sim K), central corneal thickness, and posterior corneal power. Statistical analysis was performed to determine the correlation between the postoperative posterior corneal power and other variables. An empirical formula was generated to predict the postoperative posterior corneal power. The net corneal power was calculated based on the new formula and Gaussian optics formula in an additional 31 eyes that underwent myopic LASIK and compared to the Orbscan total optical power map. The net corneal power was retrospectively applied to calculate the IOL power in an additional 10 patients who underwent cataract extraction after myopic LASIK. The back-calculation for emmetropic IOL power was performed and compared to the IOL power derived from the net corneal power.

Results

By using multiple linear regression, a formula to predict postoperative posterior corneal power can be computed from postoperative Sim K, central corneal thickness, and the amount of myopia treated with R
2
of 0.63 (standard error = 0.25) (
P
<.05). The net corneal power was highly correlated to the total optical power (R
2
=0.96); no statistically significant difference (paired
t
test) was noted (
P
>.05). The error of the IOL power derived from the net corneal power was −0.30±0.20 diopters.

Conclusions

Corneal power after myopic LASIK can be estimated using postoperative Sim K, central corneal thickness, and the amount of myopia treated, which can be used for the assessment of IOL power after myopic LASIK. [
J Refract Surg
. 2008;24:946–951.]
Adaptive Calibration of Dynamic Accommodation—Implications for Accommodating Intraocular Lenses
Authors: Schor Clifton M. , Bharadwaj Shrikant R.
Published: September 2019

Purpose

When the aging lens is replaced with prosthetic accommodating intraocular lenses (IOLs), with effective viscoelasticities different from those of the natural lens, mismatches could arise between the neural control of accommodation and the biomechanical properties of the new lens. These mismatches could lead to either unstable oscillations or sluggishness of dynamic accommodation. Using computer simulations, we investigated whether optimal accommodative responses could be restored through recalibration of the neural control of accommodation. Using human experiments, we also investigated whether the accommodative system has the capacity for adaptive recalibration in response to changes in lens biomechanics.

Methods

Dynamic performance of two accommodating IOL prototypes was simulated for a 45-year-old accommodative system, before and after neural recalibration, using a dynamic model of accommodation. Accommodating IOL I, a prototype for an injectable accommodating IOL, was less stiff and less viscous than the natural 45-year-old lens. Accommodating IOL II, a prototype for a translating accommodating IOL, was less stiff and more viscous than the natural 45-year-old lens. Short-term adaptive recalibration of dynamic accommodation was stimulated using a double-step adaptation paradigm that optically induced changes in neuromuscular effort mimicking responses to changes in lens biomechanics.

Results

Model simulations indicate that the unstable oscillations or sluggishness of dynamic accommodation resulting from mismatches between neural control and lens biomechanics might be restored through neural recalibration.

Conclusions

Empirical measures reveal that the accommodative system is capable of adaptive recalibration in response to optical loads that simulate effects of changing lens biomechanics. [
J Refract Surg
. 2008;24:984–990.]
Outcomes of Hyperopic LASIK With the NIDEK NAVEX Platform Centered on the Visual Axis or Line of Sight
Authors: Kermani Omid , Oberheide Uwe , Schmiedt Karl , Gerten Georg , Bains Harkaran S.
Published: September 2019

Purpose:

To report refractive outcomes of hyperopic LASIK with automated centration on the visual axis compared with centration on the line of sight (LOS).

Methods:

The NIDEK Advanced Vision Excimer Laser platform (NAVEX) was used to treat 181 hyperopic eyes with centration on the LOS (LOS group) and 64 hyperopic eyes with centration on the visual axis (visual axis group). The coordinates of the visual axis were digitally transferred to the excimer laser system based on the positional relationship between the LOS and the coaxially sighted corneal light reflex. All eyes were treated with a 6.5-mm optical zone and 9.0-mm transition zone. Three-month postoperative outcomes were retrospectively analyzed.

Results:

The preoperative manifest refraction spherical equivalent (MRSE) was +2.57±1.26 diopters (D) (range: 0.13 to 5.63 D) in the visual axis group and +2.46±1.32 D (range: 0.38 to 5.63 D) in the LOS group. The postoperative MRSE was +0.29±0.70 D (range: −1.00 to 1.75 D) in the visual axis group and +0.19±0.57 D (range: −0.75 to 1.75 D) in the LOS group. Postoperatively, 81% (38/47) of eyes in the visual axis group and 64% (74/116) of eyes in the LOS group were ±0.50 D. In the visual axis group, 91% (44/52) of eyes and 92% (102/109) of eyes in the LOS group maintained best spectacle-corrected visual acuity within one line compared with preoperatively.

Conclusions:

Initial experience with hyperopic LASIK centered on the visual axis indicated safe and predictable outcomes. [
J Refract Surg
. 2009;25:S98–S103.]
Steroid-induced Interface Fluid Syndrome After LASIK
Authors: Calleja Tomás Moya , Ferrer Yolanda Iribarne , Jorge Alicia Sanz , Fernández Sergio Sedó
Published: September 2019

Purpose:

To report ocular manifestations of eyes that developed interface fluid syndrome secondary to steroid-induced elevation of intraocular pressure (IOP) after LASIK. The patients presented with similiar characteristics of diffuse lamellar keratitis (DLK).

Methods:

Retrospective evaluation of four eyes of three patients with loss of vision, fluid in the lamellar interface, and IOP and topographic changes due to prolonged treatment with topical corticosteroids after LASIK.

Results:

Slit-lamp microscopy revealed an optically clear fluid-filled space between the flap and stromal bed. After early diagnosis, treatment with topical corticosteroids was stopped, resulting in quick and progressive cessation of symptoms.

Conclusions:

A steroid-induced rise in IOP after LASIK can cause transudation of aqueous fluid across the endothelium that collects in the flap interface. It is important to make an early differential diagnosis of interface fluid syndrome in DLK-suspected cases, as continued treatment with corticosteroids can produce serious visual loss. [
J Refract Surg.
2009;25:235–239.]
Multizone LASIK With Peripheral Near Zone for Correction of Presbyopia in Myopic and Hyperopic Eyes: 1-year Results
Authors: El Danasoury Alaa M. , Gamaly Tamer O. , Hantera Mohamed
Published: September 2019

Purpose:

To investigate the refractive outcomes of multifocal LASIK to create a center far, peripheral near zone in presbyopes.

Methods:

This prospective study using LASIK with a center far, peripheral near ablation algorithm comprised 68 eyes of 34 hyperopes and 78 eyes of 39 myopes. Mean patient age was 49±5.60 years for hyperopes and 46.0±3.80 years for myopes. Mean baseline manifest refraction spherical equivalent was +1.76±0.96 diopters (D) in hyperopes and −3.06±1.73 D in myopes. The mean baseline addition was +1.94±0.40 D in hyper-opes and +1.67±0.44 D in myopes. One-year postoperative outcomes are reported.

Results:

The mean postoperative spherical equivalent refraction was −0.10±0.55 D in hyperopes and −0.48±0.51 D in myopes. Two percent of eyes in each group lost two lines of best spectacle-corrected visual acuity. With the distance correction in place, 20/40 or better near uncorrected visual acuity (UCVA) (Sloan acuity) was achieved in 33% of hyperopes and 36% of myopes. A statistically significant difference was noted in postoperative near visual acuity measured by the Sloan and Rosenbaum charts (
P
<.05). Fifty-four percent of hyperopes and 48% of myopes were satisfied or very satisfied with their postoperative near UCVA.

Conclusions:

Multifocal LASIK to create a center far and peripheral near zone is safe and allows half of the patients to achieve spectacle independence. A peripheral near zone was only created in myopic treatments. [
J Refract Surg
. 2009;25:296–305.]
Faculty Professional Development in Creating Significant Teaching and Learning Experiences Online
Authors: Gülbahar Yasemin , Adnan Müge
Published: September 2019

With faculty members and instructors struggling with the massive transformational challenges stemming from technological innovation, the establishment of a digital teaching-learning culture to ensure that university graduates are ready to join the 21st-century workforce is of the utmost importance. At this juncture, the key players are those who lead the learning experience, namely faculty members and instructors. Being an experienced faculty member and possessing advanced skills of using technology does not necessarily lead to an instructor becoming an effective e-instructor. This chapter, therefore, discusses the changing nature of digital teaching and learning from the perspective of faculty members, within the framework of certain required competencies and skills that every faculty member should possess. The chapter also includes a brief overview of the literature regarding the professional development of faculty members, synchronized with reflections and experiences from an online e-Tutor course.
Enhancing Conceptual Thinking With Interactive Concept Discovery (INCOD)
Authors: Etkinda Masha , Shafrir Uri
Published: September 2019

Interactive concept discovery (InCoD), based on concept parsing algorithms (CPA), is a novel learning tool in the context of pedagogy for conceptual thinking. It supports semantic searches of key word in context (KWIC), an interactive procedure that use text analysis (concordance, collocation, co-occurrence, word frequency) and allows students to explore the course knowledge repository (KR) for discovery of conceptual contents. InCoD guides sequential teaching/learning episodes in an academic course by focusing learners' attention on conceptual meaning. InCoD is part of a pedagogical approach that is very different from the usual classroom scenario where students are given a problem-solving exercise and asked to solve it individually.
Using Concept Maps With Errors to Identify Misconceptions
Authors: Correia Paulo Rogério Miranda , Aguiar Joana , Moon Brian
Published: September 2019

Concept maps (Cmaps) have been successfully used to make knowledge structures visible. During Cmap task elaboration, novice students are likely to suffer cognitive overload, and they might avoid coping with difficult contents staying in his semantic safe territory. The authors have developed an innovative approach using Cmaps with embedded errors applied on Sero! – a cloud-based knowledge assessment platform. This chapter presents a case study involving the current use of Cmaps with errors as an assessment task capable of identifying misconceptions about the advances of molecular biology. Undergraduate students (n=86) were asked to find the errors hidden into the propositional network. The results confirmed the task challenged the students to go beyond their safe semantic territory. Misconceptions were readily identified from the students' answers providing good insights for the development of a bespoke feedback. The current data available is enough to foresee a broad range of research opportunities to readers interested in concept mapping, instruction and learning analytics.
MotherCare App for Expectant Mothers in Interior Parts of Pakistan
Authors: Khalil Muhammad Abdul Tawab , Jan Saifullah , Ali Wajid , Khan Adnan
Published: September 2019

Pregnancy, as a matter of fact, is always physically and emotionally challenging for women. Rapid physical changes with baby's growth in the womb exposes the mother to severe mood swings from short spell of merriment to long spells of anxiety and depression about upcoming child's health, its wellbeing, and so on. Most of the third world countries with their struggling economies have patriarchal social fabric, a fact that makes it worse for women of these societies to healthily tackle or seek help during gestation. The main goal of the proposed application, MothersCare, is to help the expecting mothers when they need it most. It will help them choose the right physician and request appointments from the comfort of homes, barring cumbersome wait for turn in long queues in rush hours for appointments with doctors at hospitals. This app is absolutely user-friendly in terms of simplicity of use and wide spectrum of maternal healthcare services it offers.