bluuebunny/crossref_metadata_2025 huggingface dataset:
Azadirachtin-Based Biopesticide Affects Fitness and Ovarian Development of the Natural Enemy Ceraeochrysa claveri (Neuroptera: Chrysopidae)
Authors: Gastelbondo-Pastrana Bertha , Santorum Marilucia , Scudeler Elton Luiz , Fernandes Fábio Henrique , Alvis Erasmo Manuel , Chams-Chams Linda , dos Santos Daniela Carvalho
Published: January 2025

Plant-derived biopesticides have gained attention in agriculture as a pest control method that minimizes the negative effects caused by conventional synthetic insecticides to natural enemies. Azamax™ is one of the most commercialized biopesticides in Brazil, but little is known about its effects on non-target insects such as Ceraeochrysa claveri, a non-target insect that is economically important as a pest predator, used in this study. To evaluate the toxic effects of azadirachtin on fitness and ovarian development, a total of 450 C. claveri larvae were exposed by ingestion to subdoses (36 mg/L (0.3%) and 60 mg/L (0.5%) of azadirachtin for 15 days and after that, biological parameters and ovarian development were analyzed. The doses tested corresponded to the minimum and maximum concentrations used in the field. The results demonstrated that both tested doses of the biopesticide significantly reduced survival rates, delayed and extended larval and pupal development times, caused malformations in the body, altered the ultrastructure of adult ovaries, and induced cell death in ovarian follicles. Azamax™, a biopesticide marketed as a reduced-risk insecticide, was shown to have detrimental effects on the lifespan and ovarian development of C. claveri.
Influence of Time of Weed Removal on Maize Yield and Yield Components Based on Different Planting Patterns, the Application of Pre-Emergence Herbicides and Weather Conditions
Authors: Nedeljković Dejan , Božić Dragana , Malidža Goran , Rajković Miloš , Knežević Stevan Z. , Vrbničanin Sava
Published: January 2025

The crop yield can be affected by many factors, including various levels of weed presence. Therefore, we conducted a study to evaluate the effect of time of weed removal in combination with planting pattern and pre-emergence-applied herbicides on maize yield and yield components in 2015, 2016 and 2017. The experiments were designed in a split–split plot arrangements with three replications, which consisted of the two main plots (standard/conventional and twin-row planting pattern), two subplots (with and without pre-emergence herbicide application) and seven sub-subplots (seven weed removal timings). In the dry season of 2015, maize yield was much lower (413–9045 kg ha−1) than in the wet 2016 seasons with yields of 5759–14,067 kg ha−1 across both planting patterns. Yield and yield components were inversely correlated with the time of weed removal. The application of pre-emergence herbicides delayed the critical time for weed removal (CTWR), which ranged from V4 to V10 and from V3 to V11 for standard and twin-row planting patterns, respectively. Herbicides also protected various yield components, including 1000 seeds weight and number of seeds per cob.
The Trinitarian Koinōnia and Its Socio-Economic Implications
Authors: Gobbo Wilbert Joseph
Published: January 2025

The Triune God is not indifferent to the human condition. This article, “The Trinitarian Koinōnia and Its Socio-Economic Implications,” intends to reflect on the inspiration and the critique of the Holy Trinity on human society. It aims at contributing to improving the socio-economic life of the last, the lost, and the least of society. Faith in the mystery of the Holy Trinity can influence human socio-economic relations. On the one hand, the theoretical framework used in this article is that of the classical Catholic method, which reflects on theological pillars (loci theologici). First, the article will reflect on the “theological pillar” (locus theologicus) of the Bible. It will discuss the biblical foundation of the Trinitarian koinōnia. It will then discuss another theological pillar (locus theologicus) of the human context concerning the Trinitarian koinōnia. On the other hand, another theoretical framework to be used is the deductive method. This article will examine whether there are particular socio-economic applications from the general Trinitarian koinōnia. The basic hypothesis is that there is a practical implication to the Christian faith in the Triune God. The Trinitarian oikonomia, when properly understood through, inter alia, Trinitarian koinōnia, can be the icon of the ideal human economics (oikonomia). In this article, we will privilege a systematic and systemic approach.
Template Watermarking Algorithm for Remote Sensing Images Based on Semantic Segmentation and Ellipse-Fitting
Authors: Cao Xuanyuan , Zhang Wei , Zhou Qifei , Zhu Changqing , Ren Na
Published: January 2025

This study presents a ring template watermarking method utilizing semantic segmentation and elliptical fitting to address the inadequate resilience of digital watermarking techniques for remote sensing images against geometric attacks and affine transformations. The approach employs a convolutional neural network to determine the coverage position of the annular template watermark automatically. Subsequently, it applies the least squares approach to align with the relevant elliptic curve of the annular watermark, facilitating the restoration of the watermark template post-deformation due to an attack. Ultimately, it acquires the watermark information by analyzing the binarized image according to the coordinates. The experimental results indicate that, despite various geometric and affine modification attacks, the NC mean value of watermark extraction exceeds 0.83, and the PSNR value surpasses 35, thereby ensuring substantial invisibility and enhanced robustness. In addition, the methods presented in this paper provide useful references for imaging data in other fields.
Multi-User MIMO Downlink Precoding with Dynamic User Selection for Limited Feedback
Authors: Bakulin Mikhail , Ben Rejeb Taoufik , Kreyndelin Vitaly , Pankratov Denis , Smirnov Aleksei
Published: January 2025

In modern (5G) and future Multi-User (MU) wireless communication systems Beyond 5G (B5G) using Multiple-Input Multiple-Output (MIMO) technology, base stations with a large number of antennas communicate with many mobile stations. This technology is becoming especially relevant in modern multi-user wireless sensor networks in various application scenarios. The problem of organizing an MU mode on the downlink has arisen, which can be solved by precoding at the Base Station (BS) without using additional channel frequency–time resources. In order to utilize an efficient precoding algorithm at the base station, full Channel State Information (CSI) is needed for each mobile station. Transmitting this information for massive MIMO systems normally requires the allocation of high-speed channel resources for the feedback. With limited feedback, reduced information (partial CSI) is used, for example, the codeword from the codebook that is closest to the estimated channel vector (or matrix). Incomplete (or inaccurate) CSI causes interference from the signals, transmitted to neighboring mobile stations, that ultimately results in a decrease in the number of active users served. In this paper, we propose a new downlink precoding approach for MU-MIMO systems that also uses codebooks to reduce the information transmitted over a feedback channel. A key aspect of the proposed approach, in contrast to the existing ones, is the transmission of new, uncorrelated information in each cycle, which allows for accumulating CSI with higher accuracy without increasing the feedback overhead. The proposed approach is most effective in systems with dynamic user selection. In such systems, increasing the accuracy of CSI leads to an increase in the number of active users served, which after a few cycles, can reach a maximum value determined by the number of transmit antennas at the BS side. This approach appears to be promising for addressing the challenges associated with current and future massive MIMO systems, as evidenced by our statistical simulation results. Various methods for extracting and transmitting such uncorrelated information over a feedback channel are considered. In many known publications, the precoder, codebooks, CSI estimation methods and other aspects of CSI transmission over a feedback channel are separately optimized, but a comprehensive approach to jointly solving these problems has not yet been developed. In our paper, we propose to fill this gap by combining a new approach of precoding and CSI estimation with CSI accumulation and transmission over a feedback channel.
Heterogeneous and Interactive Effects of Multi-Governmental Green Investment on Carbon Emission Reduction: Application of Hierarchical Linear Modeling
Authors: Zhang Yi-Xin , Zhang Yi-Shan
Published: January 2025

Although both prefectural governmental green investment (GGI_city) and provincial governmental green investment (GGI_prov) have potentially diverse impacts on prefectural cities’ carbon emission reduction (CER), previous studies have rarely examined the effects of governmental green investment (GGI) on different indicators of CER such as total carbon dioxide emissions (CE), carbon emissions intensity (CEI) and per capita carbon emissions (PCE) in the context of prefectural cities nested in provinces in China. In our research, six hierarchical linear models are established to investigate the impact of GGI_city and GGI_prov, as well as their interaction, on CER. These models consider eight control factors, including fractional vegetation coverage, nighttime light index (NTL), the proportion of built-up land (P_built), and so on. Furthermore, heterogeneous impacts across different groups based on provincial area, terrain, and economic development level are considered. Our findings reveal the following: (1) The three indicators of CER and GGI exhibit significant spatial and temporal variations. The coefficient of variation for CEI and PCE shows a fluctuating upward characteristic. (2) Both lnGGI_city and lnGGI_prov have promoted CER, but the impact strength of lnGGI_prov on lnCE and lnPCE is more pronounced than that of lnGGI_city. GGI_prov can strengthen the effect of GGI_city significantly for lnCE. Diverse control variables have exerted significant impacts on the three indicators of CER, albeit with considerable variation in their effects. (3) The effect of GGI on CER is significantly heterogeneous upon conducting grouped analysis by provincial area size, terrain complexity, and economic development level. The interaction term lnGGI_city:lnGGI_prov is stronger in the small provincial area group and simple terrain group. Among the control variables, economic Development Level (GDPpc), the logarithm of gross fixed assets investment (lnFAI), NTL, and P_built exhibit particularly pronounced differences across different groups. This study provides a robust understanding of the heterogeneous and interactive effects of GGI on CER, aiding in the promotion of sustainable development.
Enhancing Invoice Processing Automation Through the Integration of DevOps Methodologies and Machine Learning
Authors: Dragomirescu Oana-Alexandra , Crăciun Pavel-Cristian , Bologa Ana Ramona
Published: January 2025

In today’s rapidly evolving digital landscape, organizations are increasingly seeking systemic approaches to optimize their financial operations, particularly in invoice processing. Traditional methods of invoice management, which are heavily reliant on manual labor, not only incur significant costs but also contribute to inefficiencies, delays, and resource wastage. This article presents an integrated framework that combines DevOps methodologies and machine learning (ML) to transform invoice processing into a scalable and sustainable operation. By leveraging system dynamics and automation, the proposed Proof of Concept (PoC) addresses interconnected challenges, such as reducing labor dependency, enhancing operational intelligence, and minimizing environmental impact. The PoC framework includes dynamic model training, testing, deployment, and monitoring, enabling adaptive and resilient solutions aligned with evolving business needs. Findings from a survey highlight the potential of these integrated approaches to streamline processes, reduce errors, and optimize resource utilization while also identifying barriers to widespread adoption. By combining ML’s predictive power with DevOps’ agility, the framework not only advances automation but also provides a path toward sustainable financial operations in an interconnected and data-driven economy.
Fake news: signs and grounds for classification
Authors:   Financial University under the Government of the Russian Federation, Bartashevich D. A.
Published: January 2025

The article presents a study of fake news and various interpretations of this concept, as well as the classifications of Russian and foreign scientists regarding this phenomenon and the basis for these classifications. In addition, the author of the work has derived his own definition of fake news and provides the author's classification of the levels of fake news that we observe in the modern world, considers the concept of «post-truth», and the modern media field, which creates all the conditions for the emergence of this type of news.
The utopian dimension of the architectural projects of the Russian avant-garde
Authors:   Moscow Institute of Architecture and Civil Engineering, Savluchinskaya A. D. ,   Moscow Humanitarian and Technological University
Published: January 2025

The article is devoted to the study of utopian ideas realized in the form of urban planning projects of the avant-gardists of 1920-1930. Using the example of six conceptual projects, the author analyzes the general trends of objectification of ideas about a better future during the destruction of the old and the formation of a new world. Exploring the transformation of the archetype of the ideal city through the eyes of the architects of his time, the author makes an attempt to systematize ideas about the ideal structure of the developing Soviet world. In the course of the research, the special interest of architects in the household structure of life, the organization of collective work and recreation, the relationship of man with nature is noted. Attention is focused on the transformation of attitudes towards an ideal city, namely, the transition from fantasy to a task requiring a design solution.
Deep Learning for Predicting Biomolecular Binding Sites of Proteins
Authors: Mou Minjie , Zhang Zhichao , Pan Ziqi , Zhu Feng
Published: January 2025

The rapid evolution of deep learning has markedly enhanced protein–biomolecule binding site prediction, offering insights essential for drug discovery, mutation analysis, and molecular biology. Advancements in both sequence-based and structure-based methods demonstrate their distinct strengths and limitations. Sequence-based approaches offer efficiency and adaptability, while structure-based techniques provide spatial precision but require high-quality structural data. Emerging trends in hybrid models that combine multimodal data, such as integrating sequence and structural information, along with innovations in geometric deep learning, present promising directions for improving prediction accuracy. This perspective summarizes challenges such as computational demands and dynamic modeling and proposes strategies for future research. The ultimate goal is the development of computationally efficient and flexible models capable of capturing the complexity of real-world biomolecular interactions, thereby broadening the scope and applicability of binding site predictions across a wide range of biomedical contexts.
THE EFFECT OF PROVIDING HEALTH EDUCATION ABOUT MENSTRUATION ON READINESS OF STUDENTS TO FACE MENARCHE
Authors: Khairunnsa  , Ningsih Sri Ratna
Published: January 2025

Menarche is the onset of menstruation, typically occurring between the ages of 10 and 16. Adolescents who are unprepared to face menarche may develop feelings of rejection toward this physiological process, viewing menstruation as something harsh and threatening. Adequate education and information about menstruation are crucial for female students to be well-prepared for menarche. This study aims to assess the effect of health education on menstruation on female students' readiness to face menarche. The research employed a cross-sectional method with a pre-experimental design using a one-group pre-test and post-test approach. The sampling technique used was purposive sampling. The data analysis was conducted using the nonparametric Wilcoxon matched pairs test. The results showed a significant improvement in students' readiness after receiving health education, with a p-value of 0.000 (0.05). The study concludes that health education significantly enhances students' readiness to face menarche. It is recommended that schools collaborate with healthcare professionals to provide menstruation education, ensuring that students are better prepared for menarche.
THE INFLUENCE OF ATTACHMENT EDUCATION AND INFANT POSITIONING ON BREASTFEEDING SUCCESS
Authors: Purwaningsih Heni , Istiqomah Istiqomah
Published: January 2025

Background: Breastfeeding is essential for the physical and emotional health of both mother and baby. Proper breastfeeding techniques, including correct position and attachment, enhance bonding and provide optimal nutrition for the baby. Incorrect techniques can lead to issues like breast pain, sore nipples, and reduced milk production. Objective: to determine the effect of education on attachment and position of the baby on the success of breastfeeding. Method: The research used a pre-experimental approach with the One-Group Pretest-Posttest Design. The population of mothers who had just given birth at PKU Muhammadiyah Hospital Surakarta. The number of samples was 21 breastfeeding mothers using purposive sampling. The breastfeeding success instrument used the LATCH score checklist and educational media used props (phantoms and leaflets). Data Analysis used the Wilcoxon Signed Rank Test. Results: showed that most mothers were aged 26-35 years, had a high school education and were working mothers. Before being given education, most mothers after giving had a successful breastfeeding process that was less effective. After being given health education, it was known that most mothers had a successful breastfeeding process that was effective. That education on the position and attachment of the baby affected the success of the breastfeeding process p-value 0,000. Conclusion: There is an effect of education on the position and attachment on the success of breastfeeding.
Paradigms of Interpretation of Nishida Kitar?'s Teaching on Pure Experience in Foreign English-language Studies
Authors:   Pushkin Leningrad State University, Romanenko A.S.
Published: January 2025

Introduction. The article identifies research paradigms for interpretation of Nishida’s early philosophy, presented in English-language scholar studies. The doctrine of pure experience is characterized by: a) substantial proximity to the traditions of Far Eastern, Zen Buddhist thought; b) lack of sustained attention to the texts of Eastern philosophy; c) active assimilation of Western philosophical teachings concepts and principles. Content. Nishida's early philosophy is interpreted in foreign publications within the boundaries of three paradigms, two of them are marked by a particular character, one is of an intercultural nature. The first paradigm sees Nishida's early philosophy as a reception of Western philosophical concepts in Japan, the second one presents this philosophy as a form of development of the ideas of Buddhist Far Eastern philosophy, in the third paradigm the doctrine of pure experience is interpreted in the context of a dialogue between the West and the East philosophical traditions.

Conclusions. The first research paradigm brings Nishida's early philosophy closer to the Western intellectual tradition (empiricism, idealism, mysticism, etc.). The assessment is made on the basis of the Japanese thinker's steady practice of using the concepts and principles of Western philosophical culture. The central conclusion of the second group of studies is the position on the substantial closeness of the doctrine of pure experience and Zen Buddhist philosophy. The third approach focuses on the role of the philosophy of pure experience as a functional element mediating the dialogue between Western and Eastern traditions by creating a new philosophical language. The article emphasizes the relevance of the third paradigm due to the possibility of resolving the contradiction between the first two, as well as its correlation with Nishida's teachings.
The Simulation Phenomenon in Postmodern Society
Authors:   Voronezh State Technical University, Avdeenko E.V.
Published: January 2025

Introduction. The modern stage of society's development in the socio-humanitarian literature is often interpreted as a postmodern period. This characteristic, among other factors, is associated with a large role in the culture of the philosophy of postmodernism. The author of the article believes that the philosophy of postmodernism can be considered both an ideological and theoretical reflection of the modern society realities and an essential element of this social reality. One of the main concepts by which representatives of the philosophy of postmodernism explain modern social reality is the concept of simulation. The study of the simulation phenomenon and its impact on various aspects of public life is an urgent problem that allows us to explain many social processes and develop recommendations for countering the negative consequences of this phenomenon. Content. To achieve the purpose of the study, an attempt was made to reveal the specifics of postmodern society, focusing on simulation as its characteristic feature. It has been shown that simulacra are the main tool of manipulation in postmodern society. The position is substantiated that the simulacrum is a transformed form of movement of social and cultural information. The main forms and types of simulacra functioning in the system of interactions of postmodern society are revealed. The interpretation of the public consciousness manipulation and social behavior by postmodernists is analyzed, indicating not only the substitution of meanings, but also the creation of missing meanings of the sign system in order to form a social ersatz agreement. Simulation tools are simulacra, which are planted by mass media. The study also examines the essence and role of virtual reality, which is formed on the basis of digital technologies.

Conclusions. The basic methodological and ideological principles of postmodern society were laid down by the philosophy of postmodernism. The dominant characteristic of postmodern society is simulation, which functions through movement in the public consciousness of simulacra. In postmodern philosophy, the phenomenon of manipulation of social behavior is interpreted as the construction of a false picture based on purposeful simulation. The media, which play the role of a communication environment that creates the possibility of implementing a simulation mechanism, are essential in the manipulative process.
Theoretical Aspects of the Formation of Socio-cultural Identity of Modern Adolescents With Signs of Giftedness
Authors:   Chelyabinsk Institute for Education Development, Markina N.V. , . Kachuro I.L. ,   Chelyabinsk State University, Morozova M.I. ,   Pushkin Leningrad State University
Published: January 2025

Introduction. The relevance of the study is due to the need to substantiate the pedagogical conditions and mechanisms for creating an event-organized educational space that ensures the formation and development of social responsibility and socio-cultural, civic identity of modern adolescents. This problem is especially acute in relation to programs for the support and development of gifted schoolchildren, the implementation of their project activities and social initiatives. The article reveals the typology of the socio-cultural identity of modern gifted schoolchildren who have different experiences of immersion in the event-based educational space. The theoretical substantiation of this typology, the clarification of the concept of "socio-cultural identity", the analysis of the possibilities of collective creative activity in the context of its formation constitute the novelty of the study.

Materials and methods. The study involved 53 students of the tenth and eleventh grades. The organization of the study includes a logical and psychological analysis of the key concepts of the study, theoretical modeling, factor analysis. To empirically verify the typology of socio-cultural identity, the results of a study of socio-psychological factors of the personal dynamics of gifted adolescents and high school students who participated in shifts at the International Children's Center "Artek" were used.

Results. The concept of "sociocultural identity" of a person (SCI) is specified – it is "an integrative characteristic of a person, given by the conjugation of readiness for identity of a person with his culture (subculture) with his readiness for social-group identity, which reveals openness to personal self-determination and existential openness to constructive social interaction with significant others". Based on theoretical modeling and the relationship of vectors of readiness for cultural and social identity, a typology of sociocultural identity of a person is proposed (pronounced, false, immature, marginal, optimally open to psychological and pedagogical mechanism and conditions of education). The criteria of SCI are designated.

Discussion and conclusion. The results of the article will allow to verify the proposed typology of sociocultural identity of modern teenagers and the algorithm for determining the designated criteria of SCI. As a prospect, it is advisable to designate the study of the structure of sociocultural identity of modern teenagers, a comparison of the features of sociocultural identity of academically successful teenagers and teenagers demonstrating special success in the field of art
Organizational and Pedagogical Conditions of Choosing the Topic of Scientific Research by Students of Higher Education Institutions
Authors:   Chelyabinsk State University, Batina E.V. , Kozhukhova I.V. ,   Chelyabinsk State University
Published: January 2025

Introduction. Formation of qualities such as activity, independence, responsibility and readiness for choice in general and educational choice in particular in conditions of uncertainty (features of VUCA-world) is considered by the authors in the context of building educational relations between teacher and students. The study was conducted to identify and substantiate the organizational and pedagogical conditions of interaction between a supervisor and students that promote goal-setting and active, independent, conscious and responsible choice of the topic of scientific research by students. The authors model the space of educational relations and consider the organizational and pedagogical conditions that promote the manifestation of “self-governing” position of students in the choice of the topic of scientific research on the example of interaction between supervisor and students in the choice of research topic, which constituted the novelty of the study.

Materials and methods. The study uses theoretical methods - analysis and synthesis, comparison, concretization and generalization, pedagogical modeling, as well as empirical method of analysis of choice argumentation, the method of D. A. Leontiev, E. Y. Mandrikova “Subjective quality of choice”, based on the analysis of retrospective reflection of students.

Results. Based on the application of the modeling method, the coordinates of the space of educational relations in the system of supervisor-student in the choice of the topic of scientific research are set: normative-regulatory, perspective-orienting, activity-stimulating and communicative-informational. The authors consider in detail the organizational and pedagogical conditions of each coordinate of the space of educational relations between supervisor and students on the example of practical experience of Chelyabinsk State University. Discussion and conclusion. The implementation of organizational and pedagogical conditions in accordance with the chosen model of the space of educational relations of the supervisor and students will allow the latter to take and develop a “self-governing” position not only in the process of choosing a topic of scientific research, but also in general in the implementation of educational choice. Regular purposeful interaction on equal scientific supervisor and students on the basis of jointly defined rules also allows to reduce the emotional stress of students in the process of preparation of coursework, to stimulate them to further search and development in research activities.
The impact of pole acrobatics training on structural and functional changes in the muscles of female athletes
Authors: Antonova H.P.
Published: January 2025

Pole acrobatics is a physically demanding sport requiring a high level of coordination, reaction speed, and muscular endurance. In addition to influencing the functional state of the ner­vous system, intense training induces structural changes in muscle and adipose tissue. In this study, we used ElectroNeuroMyoGraphy (ENMG) to assess sensorimotor responses and body composition analysis using the Tanita analyzer (Tanita Europe GmbH, Japan) to identify changes in muscle mass, fat content, and electrical resistance. The study involved 20 women aged 23 to 40 who had been regularly practicing pole acrobatics for over 18 months. The participants were divided into age groups, but no statistically significant differences were found by age, allowing the entire cohort to be analyzed as a single group. ENMG was conducted to evaluate the muscle response of the arms to stimulation of the wrist and elbow, and to detect asymmetry between the right and left sides of the body. Body composition analysis included measurements of fat content, Fat-Free Mass (FFM), and electrical resistance for the arms, legs, and torso. The results showed the presence of asymmetry in the functional activity of the arm muscles, particularly in terms of nerve signal amplitude and reaction latency. It was found that the reaction latency of the right arm differed significantly from that of the left (p<0.05). Body composition analysis also revealed differences in resistance and fat content between the right and left limbs, indicating uneven distribution of physical load. Correlation analysis demonstrated an inverse relationship between fat tissue levels and functional muscle activity, sugges­ting that body composition affects the efficiency of the neuromuscular system. This study demonstrates that regular pole acrobatics training can induce adaptive changes in both the ner­vous and muscular systems.

Keywords: neural asymmetry, electroneuromyography, body composition.
Pregunta a un científic@. Estrés nucleolar en cáncer
Authors: Gómez Cabello Daniel , Aguilar Morante Diana , Bernal Bayard Joaquín , López Igual María Rocío
Published: January 2025

2º episodio de videos divulgativos de “Pregunta a un Cientific@”. Este episodio habla del estrés Nucleolar de las células, y su implicación en la formación del tumor.

Su función es el conocimiento de cómo funciona la biología molecular y celular del cáncer, de una forma muy sencilla y divulgativa. El recurso va dirigido a todos los públicos, siendo muy útil para el alumnado de carreras relacionadas con ciencia.

Es idóneo para explicar el estrés Nucleolar en cáncer que consiste en que las células tumorales son adictas a la producción de proteínas para mantener e incrementar el crecimiento celular. Este exceso de síntesis de proteínas genera un estrés del orgánulo principal para desarrollar los ribosomas, que son las “fábricas de proteínas”.

Se espera una mayor curiosidad y conocimiento de como existen diferentes estrategias para curar el cáncer, siempre partiendo de la investigación básica para llegar a poder ser utilizado en la medicina del futuro.
Rekonstruksi Penyelesaian Sengketa Perlindungan Konsumen pada Pihak Ketiga sebagai Upaya Transformasi Ekonomi Digital
Authors: Gumilar Egi Rivaldi , Sitanggang Matthew Jakaria , Ketaren Saher Remal Agungta , Everoes Muhammad Ezzat
Published: January 2025

Kehadiran e-commerce saat ini menawarkan kemudahan bagi pengguna, seperti kenyamanan, variasi pilihan, aksesibilitas, penelusuran, perbandingan harga, serta kemudahan bertransaksi dari mana saja dan kapan saja. Namun, e-commerce dinilai sangat rentan karena posisi pelaku usaha sedikit lebih diuntungkan daripada posisi konsumen yang dapat mengakibatkan konsumen menjadi lebih lemah daripada pelaku usaha sehingga menimbulkan ketidakpuasan dan kerugian. Belum lagi e-commerce juga membawa beberapa tantangan yang berkaitan dengan hak-hak konsumen, privasi data pribadi, sistem keamanan, kualitas produk, dan penyelesaian sengketa. Upaya untuk melindungi konsumen dan pelaku usaha di Indonesia telah diatur dalam Undang-Undang Nomor 8 Tahun 1999 tentang Perlindungan Konsumen (UUPK). Namun, UUPK kurang relevan dan membutuhkan rekonstruksi mengingat timbulnya masalah-masalah baru dalam e-commerce dan financial technology khususnya dalam menangani penyelesaian sengketa dan perlindungan konsumen pada pihak ketiga. Dalam penelitian ini, metode yang digunakan adalah pendekatan perundang-undangan (statute approach) dan pendekatan konseptual (conceptual approach). Hasil dari penelitian ini membuktikan bahwa penyelesaian sengketa konsumen di era digital menjadi tantangan besar sebab terdapat tumpang tindih kewenangan antarlembaga, khususnya BPSK dengan Kementerian Perdagangan RI. Hal ini dapat terjadi karena UUPK belum secara eksplisit mengatur tentang pembagian kewenangan antara BPSK dan Kementerian Perdagangan RI dalam penanganan sengketa konsumen dalam transaksi digital. Diperlukan penyempurnaan hak dan kewajiban serta tanggung jawab konsumen dan pelaku usaha sebagai langkah preventif dan memperjelas tanggung jawab pelaku usaha, juga mendorong penguatan kelembagaan yang berkorelasi dengan perlindungan konsumen.
Software educativo en el rendimiento académico de los estudiantes de la Universidad Estatal Amazónica, Ecuador
Authors: Zambrano-Vera David , Zambrano-Tapia Jennifer , Del Corral-Villarroel Víctor , Vinocunga-Pillajo Reni
Published: January 2025

Low performance in Mathematics I at the Amazonian State University (UEA) highlighted the need to implement technological solutions to optimize learning. The study aimed to evaluate the impact of educational software on the academic performance of first-semester students. Using a quasi-experimental design, a total of 121 participants were divided into an experimental group (EG) with 29 students and a control group (CG) with 31 students, which were used without modifications. Participants were assessed through questionnaires and written tests, alongside an initial interview with the program director. The analysis methods included Fisher-Snedecor and t-Student tests to compare the groups. The results showed that both groups had homogeneous levels in the initial Pretest (mean scores of 7.4140 and 7.0323, respectively), ensuring equitable conditions before the intervention. At the end of the study, the EG achieved a significantly higher mean score in the Postest (14.0690 versus 10.4194 for the CG), demonstrating a positive impact of the software on learning. Additionally, 86.21% of the students reported increased motivation, and 79.31% highlighted improvements in teacher-student interaction. These results suggest that educational software is effective in overcoming the limitations of traditional methods. To apply it in other contexts, it is essential to ensure adequate technological infrastructure, train teachers in digital competencies, and design content tailored to the specific needs of students, considering both their initial preparation level and learning styles.
DEVELOPMENT TRENDS OF STRATEGIC PARTNERSHIPS IN AGRIBUSINESS
Authors:   Kyiv National Economic University named after Vadym Hetman, DEMIANENKO Serhii
Published: January 2025

The work examines the problematic aspects of the development of strategic partnerships in the agricultural business of Ukraine. The research was conducted through the prism of strategic partnerships with high-commodity agro-industrial formations (agricultural holdings), as vertically integrated business structures, which operate in the production of agricultural products, including processing, storage, trading, including export to international markets, financing, relations with the state. For all these activities of agricultural holdings, there is a strategic partnership with landowners, from whom agricultural holdings lease land, farmers, as subcontractors of the production of various types of products, suppliers of material and technical resources, foreign business organizations in the process of exporting agricultural products and food, particularly on EU markets. The problematic aspects of our research are a correction of the directions of the strategic partnership in conditions of the post-war period. It includes renovation of agricultural land that suffered as a result of military operations, the destruction of the irrigation system as a result of the ruin of the Kakhovsky water reservoir, and the destruction of irrigation systems in other regions of Ukraine. It is also important to have a direct strategic partnership in agricultural business and the problematic aspects of rural areas development, where the interests of agricultural business, local communities and the state intersect. This level of partnership will directly contribute to the success of the post-war recovery, and not only in agricultural business, but also in the whole economy of the country.
PARTNER INTERACTION OF BUSINESS ORGANIZATIONS IN THE CONDITIONS OF THE NEW NORMALITY
Authors:   Kyiv National Economic University named after Vadym Hetman, SAHAIDAK Mykhailo , SEMENIUK Andrii ,   Kyiv National Economic University named after Vadym Hetman
Published: January 2025

The essence of the concepts of “interaction”, “partnership”, “partner interaction” that occurs between enterprises, institutions and organizations of the HoReCa market is defined. An author's approach to the formation of a trust funnel of partners in the HoReCa market based on key principles and elements of partnership interaction is proposed. The types of partnerships are systematized based on responsibility and participation in the activities of the business organization, coordination of its activities depending on the reason for the creation, implementation and development of partnership interaction. Forms of strategic partnership are distinguished according to the degree of deepening of interaction, cooperation and pooling of resources. Six principles of effective partnership have been established, with a focus on the creation and development of partnership interaction.
EUROPEAN STRATEGIC PARTNERSHIP: MODERN CHALLENGES AND OPPORTUNITIES
Authors:   Zaporizhzhia National University, METELENKO Natalya , VORONKOVA Valentyna ,   Zaporizhzhia National University, NIKITENKO Vìtalina ,   Zaporizhzhia National University, SILINA Irina ,   Zaporizhzhia National University
Published: January 2025

The paper analyses the European strategic partnership as a political and strategic association of countries focused on achieving common goals in various fields, such as security, economy, politics, culture and social issues. The author reveals the directions of the European integration vector of strategic partnership, among which a special place is occupied by the Eastern Partnership, launched by the European Union in cooperation with the countries of Eastern Europe and the South Caucasus. A special place is occupied by the EU-NATO strategic partnership, which has close relations and cooperates in many areas, including security and defence. It is proved that cooperation between the European Union (EU) and Ukraine is an important and comprehensive area of the European integration vector of the strategic partnership, which is based on the EU-Ukraine Association Agreement signed on 21 March 2014 and entered into force on 1 November 2017. The European partnership is studied in terms of advantages and disadvantages and it is determined that the effectiveness of the European Partnership may depend on many factors. Challenges to European integration, such as political disputes, corruption, social inequalities and others, and the need for countries to respond to these challenges, implement reforms and comply with their obligations to the EU are analysed. The author substantiates the security strategy of the European Union, which is based on the principles of common security and responsibility. The concept of the European Neighbourhood Policy (ENP), which is aimed at cooperation with neighbouring countries and aims to strengthen stability, security, prosperity and democracy in the regions, "privileged and differentiated partnership" is distinguished and analysed. It is concluded that the Euro-strategic partnership is aimed at enabling the parties to work together on economic, political, and social issues, and to effectively manage challenges, including political, economic, and geopolitical risks, in order to achieve common goals and promote sustainable development and cooperation.
Completude dos dados de tuberculose pulmonar em adultos notificados em Belo Horizonte, Minas Gerais, de 2001 a 2020
Authors: Freitas Giselle Lima de , Oliveira Beatriz do Carmo Veloso de , Spelta Larissa Solari , Quintero Lívia Cerf , Rabelo Juliana Veiga Costa , Gontijo Thiago Gomes , Arcêncio Ricardo Alexandre
Published: January 2025

Objetivo: analisar a completude das fichas de notificação e do acompanhamento mensal dos casos de TB pulmonar em adultos notificados em Belo Horizonte, entre 2001 e 2020. Métodos: trata-se de um estudo descritivo dos casos de tuberculose pulmonar em adultos, notificados no Sistema de Informação de Agravos e Notificação de Belo Horizonte, abrangendo o período de 2001 a 2020. A completude dos campos foi classificada em “excelente”, para valores iguais ou superiores a 90%; “regular”, para aqueles entre 70 e 89,9%; e “ruim”, para índices abaixo de 70%. Resultados: foram notificados 16.904 casos de tuberculose no período em questão. Observou-se que a completude das informações sociodemográficas foi classificada como regular ou ruim. Quanto à completude, os dados relacionados à situação clínica e ao encerramento dos casos foram classificados como regulares; já os dados referentes aos exames de diagnóstico, ao acompanhamento e ao tratamento diretamente observado foram classificados como ruins. Apenas as variáveis de preenchimento obrigatório alcançaram uma completude classificada como excelente. Conclusão: o não preenchimento ou o preenchimento inadequado das fichas de notificação gera uma falsa impressão de completude, situação essa que pode comprometer a identificação precisa da realidade da doença e das possíveis repercussões do tratamento.
Hospital universitário e gestão do sistema de saúde: uma trajetória positiva de integração
Authors: Carmo Maria do , Andrade Eli Iôla Gurgel , Mota Joaquim Antônio César
Published: January 2025

In Brazil, University Hospitals have had different forms of participation within the health system. Since the 1980´s they have become more relevant with the reduction of services provided by the philanthropic and private hospitals to the public health system. This work intends to describe and analyze how the University Hospital (Hospital das Clinicas) of the Federal University of Minas Gerais (HC-UFMG) joined the health system of the city of Belo Horizonte, in the period between 1996 and 2004, within the national context of both the National Public Health System (SUS, in Brazil) and the policies introduced to the UH. Bibliographical and documental research was carried out to learn more about the relationship of the UH with the health system throughout the years, as well as the specificities of the relationship between the UH and the health system. Through semi-structured interviews, we have identified factors that can either help or hinder integration in the eyes of the actors involved in the process. Despite the conflicts created by the confronting of powers and practices instituted in the UH, besides the new municipal management challenge brought by the management of a University andTeaching Hospital, the experience has been positive. There has been an enlargement and more service user's access equity, helping to reduce the difficulties of the health system. The teaching activities have been enlarged, and there have also been financial and organizational gains. Over a decade after its implementation, it is useful in the discussion about new and urgent changes in the UH sustainability and organizational structure of the UH within the Brazilian health system.
O significado de meio ambiente na visão dos atores sociais do município de Muzambinho-MG
Authors: Baroni Fabíola Carvalho de Almeida Lima , Lana Francisco Carlos Félix
Published: January 2025

The conception of environment may be responsible for how people deal with environmental problems. In general, in small towns these problems do not have big impact and thus, do not receive proper attention. This paper describes a case study with a qualitative approach that was carried out in Muzambinho, Minas Gerais. It aims to understand what the conception of environment is to the surveyed social actors. Since the city was considered to be a place of differences, all municipal secretaries, urban and rural associations, and institutions related to environmental and health areas participated in the study. The data was collected through focus groups and document analysis techniques. Six focus groups were formed and 43 representatives from 54 invited institutions participated. Documents collected from the speech of the participants and were related to the topic were considered for the analysis. All data underwent discourse analysis. Results show that most of the participants still see the environment in a fragmented way and emphasize the questions related to the natural resources rather than the social issues. It is also clear that these resources help the humanity, and that the relationship between men and nature is an interaction, although there is a human domain. The analysis of the discourses revealed not only the way society thinks but also the way it behaves. We consider that there is an urgent need to (re)define environment, since we will only propose significant changes once we understand its complexity.
O cuidado na Saúde da Família no Vale do Jequitinhonha
Authors: Viegas Selma Maria da Fonseca , Soares Sônia Maria
Published: January 2025

This research sought to understand healthcare in family health strategy through the contact of nurses with patients. It is an ethnographic study with nurses from family health teams in the valley of the Jequitinhonha river, state of Minas Gerais, Brazil. In the understanding of structural concepts, this work examines concepts and meanings attributed to care, with a look at the local population immersed in its beliefs, values and knowledge, in which nurses live a diversity of care, according to the bases of the National Health System and a new paradigm of care: integrality, the concept of coverage and territorial responsibility.