bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluation of Supplementary Feeding (PMT) of Mung Bean Biscuits in Ced Pregnant Women
Authors: Baluntu Zulaeha , Ahmad Mardiana , Hadju Veni , Handayani Idrus Hasta
Published: February 2025

Introduction
The global prevalence of chronic energy deficiency (CED) in third trimester pregnancy is 35-75%..
Methode
The method of research was literature review based on national and international scientific journals on the evaluation of supplementary feeding of mung bean biscuits in pregnant women with chronic energy deficiency. Publications between 2019-2024 on PubMed, Google Scholar, and Semantic databases using Indonesian English keywords. “chronic energy deficiency” in pregnancy”,“mung beans”, “vigna radiata”, There were 105 articles identified. Furthermore, screening was carried out to get 68 articles, then selected abstracts, full text, open access and type of research obtained 40 eligibility articles. The final process is to read and select eligibility articles based on the criteria obtained 30 relevant articles consisting of 5 international articles and 25 national articles.
Result
The literature search results obtained thirty literature related to the evaluation of mung bean biscuit supplementation in chronic energy deficiency pregnant women. The result of the literature search found that the supplementary feeding programme for chronic energy deficiency pregnant women can overcome the problem of chronic energy deficiency by increasing the upper arm circumference. Mung beans can be used as a basic ingredient for making local food products. Mung bean biscuits for chronic energy deficient pregnant women on labour outcomes are still very limited in the research literature.
Conclusion
The mung bean has complete nutrients both macro and micro nutrients needed by pregnant women who experience chronic energy deficiency. Making supplementary food with mung beans is proven to help improve the nutritional status of chronic energy deficiency pregnant women.
Effectiveness of Mung Bean Biscuit Pmt on Arm Circumference, Weight Gain in Pregnant Women Chronic Energy Deficiency in Trimester III
Authors: Kurnianto Eka Indriani , Ahmad Mardiana , Handayani Idrus Hasta
Published: February 2025

INTRODUCTION
The World Health Organisation (WHO) states that the prevalence of Chronic Energy Deficiency (CED) in third trimester pregnant women is 35% to 75%, much greater than the incidence in the first and second trimester.
METHODS
Literature review research method based on national and international scientific journals related to the effectiveness of providing PMT green bean biscuits on Upper Arm Circumference and Weight gain of pregnant women with CED. Publications between 2019 -2024 on Pub-Med, Science Direct, Google Scholar, and Semantic databases with Indonesian and English keywords, '"additional food, green beans "green bean, biscuits "biscuits" Lila "upper arm circumference", 'weight gain" "pregnant women", and "CED". The search for articles as many as 140 articles, screened get 76 articles. then selected abstracts, full text, open access and type of research obtained 40 eligibilite articles. The final process is to read and select eligibility articles based on the criteria obtained 30 relevant articles consisting of 5 international articles and 25 national articles.
RESULTS
Mung bean formula given to pregnant women with CED for 21 days can increase body weight by 0.6 kg and Upper Arm Circumference (UAC) by 0.7 kg. Supplementary biscuits can increase the upper arm circumference and body weight of pregnant women with CED. Substitution of mung bean and other food ingredients can increase the nutritional value of supplementary food products so that they can fulfil the nutritional needs of pregnant women.
CONCLUSIONS
The use of mung beans in the preparation of supplementary food can help pregnant women with CED to increase UAC and body weight.
Harnessing Infographic Media to Improve Knowledge of Hypertension Management During Pregnancy
Authors: Aprilia Rizki , Ahmad Mardiana , Jumrah Jumrah , Handayani Idrus Hasta
Published: February 2025

Hypertension during pregnancy is a cause of morbidity and mortality in mothers and children worldwide. One of the other factors is that the level of knowledge of hypertensive pregnant women is not optimal due to the lack of information about controlling hypertension. Efforts made to improve the knowledge of pregnant women about hypertension in pregnancy are with various media health education. This research uses the literature review method by searching for sources through the Electronic Data Base. The electronic database used is google scholar which begins with determining topics and keywords for searching articles and journals. Search through PubMed, Google Scholar, and Web of Sciences, Sciences Direct. The research process includes a critical review and assessment of existing literature sources. As well as determining the topic and keywords ‘hypertension, pregnant women, infographic media, and knowledge’ for searching articles and journals in accordance with what the researcher reviewed that infographic media can provide an attractive, effective, and easily accepted form of information for pregnant women. The results show that the use of infographic media is easier to understand, fun because it does not all contain full text and then varied image colours. The findings of this literature show that infographic media can be used as a medium to increase knowledge related to the prevention of hypertension during pregnancy.
Bilateral Tuba Ovarian Tuberculosis Mimicking Ovarian Carcinoma in an 18 Year Old Woman
Authors: Iskandar Harun , Setiawati Dewi , Handayani Idrus Hasta
Published: February 2025

Background: Tuba-ovarian tuberculosis (TB) is a rare extrapulmonary form of tuberculosis that can closely mimic ovarian carcinoma, posing a diagnostic challenge due to similar clinical and imaging presentations. This case highlights the importance of considering TB in the differential diagnosis of adnexal masses, particularly in young women from TB-endemic areas.
Case Presentation: An 18-year-old woman presented with chronic pelvic pain, abdominal distension, low-grade fever, and significant weight loss over three months. Clinical examination revealed a palpable pelvic mass. Laboratory findings showed elevated CA-125 levels (420 U/mL), raising suspicion of ovarian carcinoma. Imaging studies, including pelvic MRI, demonstrated bilateral adnexal masses with ascites and omental thickening, findings suggestive of advanced ovarian malignancy. Exploratory laparotomy revealed bilateral tubo-ovarian masses, dense adhesions, and caseous material. Histopathological examination confirmed granulomatous inflammation, and Ziehl-Neelsen staining identified acid-fast bacilli. Molecular testing (GeneXpert) confirmed the presence of Mycobacterium tuberculosis. The patient was diagnosed with bilateral tuba-ovarian tuberculosis and initiated on anti-tubercular therapy (ATT). Follow-up after six months showed significant clinical improvement, resolution of masses, and normalization of CA-125 levels.
Discussion: This case underscores the difficulty in differentiating tuba-ovarian tuberculosis from ovarian carcinoma based solely on clinical, serological, and imaging findings. Early histopathological and microbiological evaluation is critical to avoid misdiagnosis and unnecessary extensive surgical interventions.
Conclusion: Tuba-ovarian tuberculosis, although rare, should be included in the differential diagnosis of adnexal masses in young women, particularly in TB-endemic regions. Timely recognition and treatment can lead to favorable outcomes, preventing undue morbidity.
Study of the physical and chemical properties and essential fatty acids of sunflower oil used for frying for a period of (1-5) hours
Authors: Alhadithi Hussein J.M. , Khashan Bilal A. , Morgab Mohammed Abd Hemed
Published: February 2025

A portion of edible sunflower oil obtained from the local market was obtained and split into six segments. One segment served as the control sample, while the other five segments were used for frying for a duration of five hours. At each hour, a sample was extracted for inspection. The study included conducting chemical and physical testing on all samples. Additionally, gas chromatography (GC) analysis was performed to track the concentrations of essential fatty acids (namely linoleic and linolenic acids) in four oil samples. The obtained findings are as follows: Following a duration of five hours of frying, the melting point experienced a reduction of 2°C, the specific weight underwent a change from 0.9178 to 0.9255, the viscosity exhibited a rise from 40.82 to 48.70 CBP, and the refractive index had a modest alteration, transitioning from 1.4722 to 1.4735. The chemical tests yielded the following results: the free fatty acid content did not exceed 0.6%, the smoking point was reduced from 285°C to 245°C, the peroxide number remained within the permitted range without any modification, and the acidity level met the required specifications. The levels of unsaturated fatty acids in the control sample were as follows: oleic acid decreased from 263 ppm to 0.173 ppm, linoleic acid decreased from 102 ppm to 8.784 ppm, and linolenic acid decreased from 339 ppm to 17.27 ppm. Unsaturated acids exhibit less stability throughout the course of frying. The stability of the oil is directly correlated with the duration of frying. In general, sunflower oil is considered one of the most suitable oils for frying and remains stable for up to 5 hours of frying. The oil's essential acid concentration drops as the frying time increases, in addition to its physical qualities.
Detection Analysis of Adolescent Girls with Unwanted Pregnancy Using the HEADSSS Approach. Study at Dr. Saiful Anwar Hospital, Malang
Authors: Priyo Utomo Rudi , Prasetyo Budi , Indrawan I Wayan Agung
Published: February 2025

Context
Teenagers are assets for the country's future, but they are also associated with a variety of difficulties. Unwanted pregnancy is one of the most common issues among young women..
Objectives
The study's goal is to use the HEADSSS Assessment to examine risk factors for unintended pregnancy and develop evidence-based recommendations to improve adolescent reproductive health.
Methods
The research is a case control study with two groups, cases and controls. Each group had a sample of 49 respondents. The inclusion criteria were young women aged 15 to 19, who were pregnant or postpartum and confessed that they did not desire the pregnancy. HEADSSS Assessment is used in data collection. The acquired data was then examined using an inferential test, logistic regression with an alpha value of 0.05.
Results
The results indicated that there were no differences between the two groups in their influence on unplanned pregnancy, as indicated by the p-values for age (p-value 0.798), education level (p-value 0.742), and marital status (p-value 0.192). After that, a logistic regression analysis of the overall HEADSSS score in connection with unintended pregnancy revealed a p-value of 0.001 for differences between the two groups. This indicates a difference between the case groups and the control group's HEADSS scores.
Conclusions
The HEADSSS evaluation has demonstrated efficacy in identifying, developing, and implementing suitable treatments for young women, ensuring that they are prepared and capable of embracing pregnancy, the postpartum phase, and the birth of their child.
Understanding The Relative Relationship Between Occupation and Investment Objectives Using Correspondence Analysis
Authors: S Veena. , Chitra Sivasubramanian R.
Published: February 2025

Purpose
The investments are being done by women of all walks of life, irrespective of age, marital status, education and occupational status. An attempt has been made to understand the relationship between the occupation and the reasons for which investments are made, namely the investment objectives. The investment objectives vary amongst the individuals and the study tries to understand those objectives preferred by women investors working in various occupations.
Methodology
For the purpose of study, women investors working in private organisation, government organisation, doing business and practising professionals have been identified. There are 12 investment objectives which have been identified for the study and responses were collected through a structured questionnaire circulated through google forms. To understand the relationship, Correspondence Analysis has been used to visualize the relationship through biplots.
Findings
The biplot has been discussed with respect to relationship between occupation and investment objectives and valuable interpretations have been made. It could be understood from the analysis, there are certain objectives preferred by women investors for their investment decisions and some objectives were not considered at all.
Practical Implications
The investment avenues offered by financial institutions should be designed and framed according to the preferred objectives of women investors and marketed accordingly.
Originality
The research article is first of its kind in understand the relative relationship between occupation and investment objectives of women investors in India and presenting the analysis through visual presentation for better understanding.
Long-Term Outcomes of Tissue versus Mesh Repair for Inguinal Hernia in India: A 45-Year Single-Surgeon, Single-Center Retrospective Analysis
Authors: K Reddy C M , Reddy K R , Reddy C J , Kishore C M , Nazeer Nabeel
Published: February 2025

This study presents a retrospective analysis of surgical interventions performed for inguinal hernia, aiming to elucidate the challenges associated with herniorrhaphy (tissue repair) and compare the overall outcomes with mesh hernioplasty (tension-free repair) in the Indian context. A survey revealed that approximately 80% of inguinal hernia repairs in India are still conducted using tissue approximation techniques, especially in rural and suburban healthcare settings, due to various underlying factors. The analysis evaluates the relative merits and drawbacks of these two surgical approaches, herniorrhaphy and mesh hernioplasty, in the management of inguinal hernias within the Indian healthcare landscape. The findings of this retrospective study provide valuable insights into the selection of appropriate surgical techniques and highlight the potential implications for patient outcomes, particularly in resource-limited settings.
Correlational Analysis of A Serve With Hand-Eye Laterality Profile Among Professional Tennis Players in Chennai
Authors: Easaki Subhashree , Mariyam Farzana S. F.
Published: February 2025

Background: Tennis serve is a crucial and complex technique. It demands a sense of timing to make precise ball-racket contact when the player tosses the ball in the air. Hand-eye laterality is one major factor that decides this contact's quality, if not the overall gameplay. Earlier studies have estimated that a contralateral hand-eye profile is seen more in professional athletes compared to the normal population. However, analysing the serve based on the players’ laterality profile is necessary to conclude if it plays a role in accuracy or not.
Objective: The analysis aims to determine the importance of hand-eye laterality profile in a tennis serve in case of accuracy among professional players.
Methodology: A group of professional tennis players was made to perform the Dominant Eye Test, according to which they were divided into two batches: A and B. Batch A comprised of players with ipsilateral profile (same side hand-eye profile), and batch B comprised of players with contralateral profile (opposite side hand-eye profile). The players were asked to demonstrate 4 types of serves based on the court markings: 1. A basic serve inside the serve box, 2. A serve towards the outer corner of the serve box (wide serve), 3. A serve towards the inner corner of the serve box (down the T) and 4. A serve towards the outer corner of the serve box with the player standing on the side where his/her dominant hand is placed opposite to the serve box (cross serve). Each serve was demonstrated 5 times by each player. Based on the number of serves placed correctly for each type out of 5 demonstrations, the accuracy of the serve was determined.
Result and Conclusion: The study concludes that hand-eye laterality plays a role in accuracy of a tennis serve in a cross, wide and down the T variation.
Evaluating Asymmetric Dimethylarginine (ADMA) as a Biomarker for Preeclampsia: A Meta-Analysis
Authors: Bansal Abhishek , P. Hadimani Chetana. , B Patil Sadanand , Zuki Bin Nik Lah Nik Ahmad
Published: February 2025

Background: Preeclampsia (PE) is a serious pregnancy-related disorder characterized by hypertension, endothelial dysfunction, and multi-organ involvement. Despite advances in understanding its pathophysiology, early diagnosis and reliable biomarkers remain critical challenges. Asymmetric dimethylarginine (ADMA) is a natural inhibitor of nitric oxide synthase (NOS) that has been implicated in endothelial dysfunction, a key feature of PE. This study aims to evaluate the potential of ADMA as an early biomarker for the detection and assessment of preeclampsia.
Methods: This systematic review and meta-analysis included 16 observational studies examining the association between serum ADMA levels and preeclampsia. Data from 767 women with PE and 896 healthy controls were analyzed to determine the mean difference in ADMA levels between the two groups. The analysis followed PRISMA guidelines, and heterogeneity was assessed using the I² statistic.
Results: The pooled analysis revealed that serum ADMA levels were significantly higher in women with preeclampsia compared to healthy pregnant controls (mean difference = 0.38 µmol/L, 95% CI: 0.11–0.65 µmol/L, p = 0.01). Significant heterogeneity (I² = 99.9%) was observed across studies. Funnel plots indicated no significant publication bias.
Conclusion: Elevated ADMA levels are associated with preeclampsia and may serve as a promising biomarker for early detection and disease severity evaluation. Despite significant heterogeneity across studies, the findings suggest ADMA's potential role in the pathophysiology of PE, particularly in endothelial dysfunction. Further prospective studies and standardization of measurement techniques are required to confirm ADMA’s clinical utility in preeclampsia diagnosis and management.
A Hybrid ML and Data Science Approach to Detect Online Fraud Transaction at Real Time
Authors: Lenka Swagatika , Tiwari Ravindra
Published: February 2025

To safeguard customers and financial institutions, the swift growth of online transactions calls for strong fraud detection systems. To identify online fraud in real time, this study suggests a mixed machine learning (ML) and data science strategy. Through the integration of many data mining methodologies, such as supervised and unsupervised learning algorithms, the research endeavours to detect trends and anomalies suggestive of fraudulent activity. A comprehensive knowledge of transaction behaviours is made possible by the methodology's emphasis on dynamic feature extraction and selection, which makes use of massive datasets made up of transactional records.
Using ensemble learning techniques reduces false positives and improves prediction accuracy. Results from experiments reveal that the hybrid model works well, outperforming conventional techniques in terms of processing speed and detection rates. Furthermore, the model's flexibility facilitates its implementation across multiple internet platforms, guaranteeing efficiency and scalability. The results highlight the value of a multidisciplinary strategy in the fight against online fraud, which will ultimately help create more secure online transaction environments. The foundation for future research targeted at improving fraud detection techniques in an increasingly digital economy is laid by this study.
Outcomes of Complex Gastroschisis
Authors: Ilhama Jafarli , Alexandra Richards , Allahverdi Musayev , Nigar Allahverdiyeva , Ines Castro-Moore , Homero Brum , Morcos Gobriel , Heydar Mammadli , Turan Mammadli
Published: February 2025

Background
Gastroschisis, an anterior abdominal wall defect, is associated with significant morbidity and mortality. This study aims to evaluate the early outcomes of neonates with complex gastroschisis and correlate outcomes with prevalent types of complications, such as a line infection and NEC. 
Methods
A retrospective review was performed at multiple pediatric surgical centers (January 2001 and December 2019). Statistical analysis of categorical variables between the cohorts of the primary closure versus silo placement was conducted and 95% confidence intervals (CI) for variables were calculated.
Results
Two hundred and thirty-four neonates with gastroschisis were identified. The cohort of neonates having undergone silo closure had a longer duration of total parenteral nutrition (TPN) (32.5 vs. 48.17; P = .006), prolonged hospitalization (40.18 vs. 54.15; P = .007) and higher incidence of concomitant of bowel atresia (0.12 vs.0.20; P= .004). There was no difference observed in survival. Multivariate logistic regression demonstrated that time to closure and number of surgeries were significantly related to LOS as an independent variable.
Conclusion
The time to silo closure is the most significant variable related to the duration of TPN and hospitalization in gastroschisis patients, determined by the number of surgeries and severity of the disease. Furthermore, NEC and line infection were high after primary closure.
Congenital Immature Orbital Teratoma with Sarcomatous Transformation Presenting as Exophthalmos: A case report
Authors: Andreassa Soares Gregório , Hamad Mehanna Samya , Costa Linhares Júlia
Published: February 2025

Background
Congenital immature orbital teratomas are rare neoplasms, with intraorbital cases presenting unique diagnostic and therapeutic challenges.
Case presentation
This report presents a patient that exhibited rapid-growing right exophthalmos since birth. Imaging studies revealed a progressively expanding lesion in the right orbital cavity and optic nerve. Following partial resection and subsequent orbital exenteration, histopathological and immunohistochemical analyses confirmed the diagnosis of immature teratoma with sarcomatous transformation. The patient underwent chemotherapy and remains under surveillance with no signs of disease recurrence.
Conclusion
This case highlights the complexities associated with diagnosis and treatment of rare orbital teratomas, contributing valuably to the existing literature.
Strangulated Left Inguinal Hernia with Jejunal Perforation Complication in Five-Day-Old Full-Term Neonate: A Case Report
Authors: Herzoni Muhammad Ilham , Ibrahim Ismar , Wahid Tb Odih Rhomdani
Published: February 2025

Background
Inguinal hernia in children is the foremost common surgical pathology and the biggest reason for referral to the pediatric surgeon. Strangulated inguinal hernia is the foremost important and dreaded complication due to strangulation of the sac contents. A rare complication of incarcerated inguinal hernia in neonates and infants is strangulation.
Case Presentation
A 5-day-old newborn male presented with a strangulated left inguinal hernia and was operated on emergently. At surgery, the hernia contained a loop of jejunal with perforation. The jejunal perforation was resected, and we performed an end-to-end anastomosis. No leakage was observed from the anastomosis. The hernia sac is then highly ligated with a non-absorbable suture.
Conclusion
Strangulated hernia in 5-day-old full-term neonates is rare. The longer the onset of the hernia, the greater the risk of complications will happen.
Machine Learning Applications in Retinopathy of Prematurity Diagnosis Using the ROP Retinal Image Dataset
Authors: Krishnan Anantha , Salman Sarkar Md. , Badavath Laxman
Published: February 2025

Purpose: Retinopathy of Prematurity (ROP) is a leading cause of childhood blindness, particularly in preterm infants. This study aims to evaluate the performance of machine learning (ML) models for ROP diagnosis using a publicly available retinal image dataset.
Methods: The study utilized the Retinal Image Dataset of Infants and Retinopathy of Prematurity (ROP) from the University Hospital Ostrava, Czech Republic. The dataset comprised 6,004 retinal images and clinical metadata, including gestational age, birth weight, and diagnosis codes. Two ML models, Random Forest and Subspace Discriminant, were implemented. Preprocessing included metadata normalization and stratified sampling into training and testing sets. Model evaluation metrics included accuracy, sensitivity, specificity, and area under the receiver operating characteristic curve (AUC).
Results: The Random Forest model achieved an accuracy of 78.62%, sensitivity of 100%, and specificity of 92.21%, indicating strong performance in predicting ROP diagnoses. In contrast, the Subspace Discriminant model underperformed, with an accuracy of 26.90% and no reliable predictions. Feature importance analysis identified gestational age and device type as key predictors.
Conclusion: The Random Forest model demonstrated significant potential for automated ROP diagnosis. Future research should explore multimodal data integration, larger balanced datasets, and advanced deep learning models to enhance predictive accuracy and clinical applicability.
Prognostic Appraisal of Sacrococcygeal Teratoma- Authors Experience and Review of literature
Authors: Gupta Rahul , Mathur Priyanshu , Agrawal Liladhar , Goyal Manisha , Gupta Arun Kumar , Babu Goyal Ram , Singh Shekhawat Narpat
Published: February 2025

Background: Sacrococcygeal teratoma is associated with malformations which may have a bearing on the outcomes of these patients. The study aimed to present its varied clinical presentation, management, and outcome analyses in our geographical region.
Methods: A prospective descriptive observational study was carried out on a cohort of paediatric patients with sacrococcygeal teratoma. All consecutive patients admitted and managed by the authors in a tertiary care teaching institute from 2011 to 2024 were studied. Patients were followed up for at least one year after surgical intervention.
Results: There were 53 patients (F: M=1:2.18). The median age at presentation was 12 days. Forty (74.47%) patients presented with swelling lower back. The patients were Altman I - 23/53 (43.39%), Altman II - 17/53 (32.08%), Altman III - 5/53 (9.43%), and Altman IV - 8/53 (15.09%). Associated major malformations were present in 9 (16.98%) patients; anorectal malformation- 4 (7.55%) patients; 3 (5.66%) were consistent with Currarino syndrome. Tumour excision and coccygectomy were performed in 52 (98.11%) patients. Histopathology revealed mature teratoma in 41/52 (78.85%), immature teratoma in 9/52 (17.31%), and malignant tumours in 2/52 (3.85%) patients. Early postoperative complications were seen in 11/52 (21.15%) patients, including 3 (5.77%) deaths. Early survival (within 3 months) was 48/53 (90.57%). Late complications (within 1 year) were seen in 8/35 (22.86%) patients.
Conclusion: Most of the sacrococcygeal teratomas are benign (mature); immature and especially malignant tumours are often seen around and beyond infancy. Mortality is due to associated major malformations, sepsis, sclerema, and tumour recurrence.
Association of Serum Calcium Levels with Menopausal Status and Risk of Health Outcomes Post-COVID-19 Vaccination: A Comparative Study
Authors: Tawfeeq Shaymaa , Jabbar Tauma Rusul , Mohammed Albobaqer Aseel Abdulameer , G. Yousif Maitham
Published: February 2025

The function of menopausal status and serum calcium level with different health outcomes has been taken into close consideration, but the influence on health after vaccination for covid-19 has been little discussed. The present research is aimed at the serum calcium levels across menopausal stages and offtakes the health problems that such vaccination can cause. The sample was female; 235 patients were aged 17–46 years with most of them domiciled in urban areas. The serum calcium levels measured in both groups of women, before and after the change in menstrual cycle were determined and the values were compared with each other. The area under the curve analysis was utilized in the study for the purpose of assessing for menopause the ability of serum calcium levels to determine the disease. The control group of premenopausal women was employed for instance what the normal levels are. The next step was the introduction of micronutrient-rich foods. In postmenopausal women, evidence from serum calcium levels indicates a significant lowering of levels compared to premenopausal women, which signifies a notable deficiency. As far as a direct response on calcium deficit is regarded, the value increase from the level of -15.05 was obvious for post-menopausal status, while pre-menopause offered protection. The calcium of serum test received the best scores for predicting menopause mechanism. It had a sensitivity percentage until 94% and a specificity percentage until 92%. On the other hand, women who barely had more than a score of 4 were at an 11.75 times risk of going through menopause. It can prove the existing correlation between serum calcium levels and menopausal status, as well as the effect on COVID-19 vaccination efficiency. The individualization of the action plan on the basis of determining species-specific needs in calcium levels revealed among women in the menopausal age by outlining the prevention strategies as well as identifying possible insufficiency and other aggravated cases among this group. The results of this study contribute to the already existing knowledge of post-vaccination health hazards. It also emphasizes the fact that the general perspective on healthcare whenever there is COVID-19 immunization becomes more balanced.
Deep Learning and AI in Detection of Oral Malignancy
Authors: Sapkal Rashmi , Supnekar Shraddha , Shete Anagha , Prakash Channe Pallavi , Desai Ashwini
Published: February 2025

Oral cancer, particularly oral squamous cell carcinoma (OSCC), remains one of the most prevalent and deadly cancers worldwide. Early detection is critical for improving prognosis and survival rates, but traditional diagnostic methods often face challenges in identifying malignancies at early stages. Recent advancements in artificial intelligence (AI) and deep learning (DL) offer promising solutions for revolutionizing oral cancer detection. This paper explores the application of AI, specifically deep convolutional neural networks (DCNNs), in detecting oral malignancies using medical imaging, histopathological data, and clinical parameters. We review existing literature, highlighting the performance of various AI models in comparison to traditional diagnostic techniques, and provide a detailed methodology for the development and evaluation of these models. The results demonstrate that AI-based approaches significantly improve diagnostic accuracy, sensitivity, and early-stage detection of oral cancers. However, challenges remain in the integration of AI systems into clinical workflows, addressing ethical concerns, and ensuring model generalizability. Future research should focus on overcoming these barriers, improving model transparency, and exploring the integration of multimodal data to enhance diagnostic performance. This study underscores the transformative potential of AI in enhancing oral cancer detection and offers directions for future clinical applications and research.
Evaluation of Mung Bean Supplementation for Anaemic Pregnant Women
Authors: Selpia Dina Riska , Ahmad Mardiana , Hadju Veni , Handayani Idrus Hasta
Published: February 2025

Background: The global prevalence of anaemia among pregnant women is 37%, which means that 4 out of 10 pregnant women experience anaemia during pregnancy, 70% of which is moderate and occurs during the third trimester of pregnancy.
Methods: Literature review research method based on national and international scientific journals on the evaluation of supplementary feeding of mung bean biscuits to anaemic pregnant women on delivery outcomes. Publications between 2019-2024 on Pub-Med, Science-Direct, Google Scholar, and Semantic databases using the keywords "anaemia in pregnancy", "mung beans", "vigna radiata", "birth outcome". 140 articles were identified then screened resulting in 87 articles, then selection was made regarding abstracts, full text, open access and type of research, 30 articles were obtained. The final process is to read and select eligible articles based on the criteria obtained 30 relevant articles consisting of 4 international articles and 26 national articles.
Result:The results of the literature search explain that anaemia in pregnancy is caused by increased iron requirements in pregnant women needed to support pregnancy, coupled with insufficient iron intake, can interfere with uteroplacental oxygenation, potentially inhibiting fetal growth and development. Providing additional food and a good diet for anaemic pregnant women can increase haemoglobin levels. Mung beans contain iron, vitamin C and zinc, and vitamin A which are necessary for the formation of haemoglobin. Giving mung beans can increase Hb levels
Conclusion: Mung beans can significantly increase blood Hb levels because they contain iron, vitamin C and zinc, and vitamin A which have many functions in the body, including the growth and differentiation of progenitor cellserythrocytes, the body's resistance to mobilisation of iron reserves throughout tissues and infections.
Uncommon Oral Manifestations and Growth Failure in A Pediatric Multisystem Langerhans Cell Histiocytosis: A Case Report
Authors: Janardhan Kavya , Khan Azmathulla , Das Mazumder Mithila , Pushpa Manjushree , Swaraj SL Akhila , S Asangi Santoshkumar
Published: February 2025

Langerhans cell histiocytosis (LCH) is a rare condition characterized by the clonal proliferation of Langerhans cells, leading to varying degrees of organ dysfunction. This report presents a challenging case of multisystem LCH in a 1-year-8-month-old female, exhibiting symptoms like gingival hypertrophy, cutaneous lesions, and failure to thrive. Diagnosis was confirmed by histopathology and immunohistochemistry, which revealed CD1a-positive Langerhans cells. The patient underwent chemotherapy, achieving significant clinical improvement. This report emphasizes the need for vigilance when evaluating pediatric patients with nonspecific symptoms and the importance of a multidisciplinary approach in diagnosing and managing this rare disorder.
Traumatic Tooth Avulsion in Adolescents: Examining Links to Aggressive Behavior, Parental Handling Expertise, and Accidental Injuries
Authors: Rajan KV Ranjeth , R Ramesh
Published: February 2025

Background
Tooth avulsion, a severe dental trauma in adolescents, results from physical aggression, road traffic accidents (RTAs), or falls. Effective management, including proper storage and prompt replantation, is vital but often hindered by inadequate parental knowledge.
Aim
This study explores associations between tooth avulsion, aggressive behavior, parental knowledge, and management practices among adolescents.
Materials and Methods
A cross-sectional study evaluated 99 adolescents (aged 9–14) presenting with traumatic dental injuries at a tertiary care hospital. Data collection included validated parental and adolescent questionnaires and clinical examinations. Descriptive statistics summarized demographic data. Chi-square tests assessed associations between aggression, socioeconomic status, and parental knowledge. Pearson and Spearman correlation analyses evaluated relationships between aggression dimensions and tooth avulsion. Statistical significance was set at p<0.05 to ensure robust conclusions.
Results
Tooth avulsion prevalence was 58.6%. Strong correlations were identified between physical aggression (r=0.896) and avulsion. Only 42% of parents demonstrated adequate emergency knowledge. Socioeconomic status (SES) influenced awareness (p<0.001). Poor outcomes (52.5%) were frequent due to delayed interventions.
Conclusion
Aggressive behaviors significantly increase the risk of dental trauma, while parental knowledge gaps hinder effective management. Educational programs targeting caregivers, schools, and communities are imperative to improve outcomes.
In Silico Molecular Docking Analysis of Diclofenac as an Inhibitor of Succinate Dehydrogenase (SDH)
Authors: Rohini P.
Published: February 2025

Succinate Dehydrogenase (SDH) plays a crucial role in cellular energy metabolism and redox signaling, making it a significant target for metabolic studies. This study aimed to investigate the inhibitory potential of Diclofenac on SDH using in silico molecular docking analysis. The crystal structure of human SDH (PDB ID: 6VAX) was retrieved and prepared by removing water molecules, adding hydrogen atoms, and assigning Kollman and Gasteiger charges using AutoDock. Diclofenac's 3D structure was retrieved from PubChem, optimized using OpenBabel, and prepared for docking by adjusting torsion angles and charges. Blind docking simulations were conducted to explore potential binding sites across the SDH structure using AutoDock with default parameters. The results revealed significant binding affinity between Diclofenac and SDH, with a binding energy of -8.18 kcal/mol. A hydrogen bond was observed with LYS498, while hydrophobic interactions with key residues, including ASN495, GLN569, and TYR543, contributed to the stability and specificity of the Diclofenac-SDH complex. These interactions demonstrated Diclofenac’s potential to inhibit SDH function by stabilizing within the enzyme’s active site. This study confirms Diclofenac’s inhibitory activity on SDH through molecular docking, aligning with prior in vivo evidence of its metabolic impact. The findings provide valuable insights into the molecular mechanism of SDH inhibition and its potential implications for metabolic disorders.
Exploring Urinary Heparin-Binding Protein as a Diagnostic Biomarker for Asymptomatic Bacteriuria in Gestational Diabetes Mellitus: Bridging Microbial Insights and Clinical Innovations
Authors: Adiga Sachidananda , Vasishta Sampara
Published: February 2025

Background: There is a high frequency of asymptomatic bacteriuria (ASB) during pregnancy among females. GDM is a strong risk factor for ASB development during the course of pregnancy because it leads to impairment of immune status and provides a favorable environment for the growth of bacteria. In this investigation, the aim was to determine the levels of urinary heparin-binding protein (UHBP) in GDM and non-GDM groups, examine the urinary heparin-binding protein levels in GDM pregnant women and the diagnostic value of UHBP for evaluation of ASB.
Methods: This was a case control study with a total of 160 participants including 80 pregnant women diagnosed with gestational diabetes mellitus and 80 healthy pregnant women. All participants were subjected to routine urine culture and microbiological tests, as well as assessment for UHBP levels. For continuous variables, Mann-Whitney U test was used and for categorical variables, Fisher’s exact test was conducted. The sensitivity and specificity of UHBP for diagnosis of culture proven cases of ASB was done using ROC curves.
Results: The levels of UHBP were notably diminished in the GDM mothers as compared to the controls (p=0.0116). During ROC curve evaluation, however, UHBP for ASB was found to be of limited diagnostic value since the area under the curve (AUC) was 0.370 for the GDM and 0.519 for the normal group. This indicates that UHBP is not a good single diagnostic marker.
Conclusion: This study underscores the potential impact of asymptomatic bacteriuria (ASB) in gestational diabetes mellitus (GDM) on neonatal health. Neonates born to mothers with GDM and ASB may face heightened risks of infections and other complications due to maternal immune dysregulation. The findings stress the importance of maternal screening to improve neonatal outcomes by mitigating risks of preterm birth and low birth weight associated with untreated ASB.
Efficacy of Sequential Lymphatic Drainage in General Medicine and Surgery: 8-Chamber Systems for Managing Early-Stage Lymphedema
Authors: Jeyaretnam cand. med Jeyatheepan
Published: February 2025

Purpose: Lymphatic drainage has best been associated with lymphedema treatment since the ancient civilization, although advanced techniques have boosted the success. The present paper aims at assessing the success of SLD, especially with reference to an 8-chamber system, in treating first and second degree lymphedema. This study, performed in Sechenov University and a network of collaborating clinics in Moscow, retained 1000 patients with a selective number of those entering a detailed quantitative dissection. The study was carried on limb size alterations, joint angles mobility and on the subjective experiences of patients after having received the MAI or instrument-based LD therapies.
Methodology: The assessment utilized kinesiological tests and measures, anthropometry, as well as data collected from surveys. Limb circumference measurements, joint mobility and overall quality of life also improved according to the patients.
Findings: The results highlight the utility of lymphatic drainage systems in a reduction of oedema, enhanced functionality of the limbs and support in the rehabilitation in the field of general medicine and surgery. This study enriched understanding of LD not limited to the medical treatment but including health improvement and post training& performing recovery.
Gastrointestinal side effects of Chemotherapy: Parent s’ Perception towards Children with Cancer
Authors: Hamzah AL-Shujairi Nariman
Published: February 2025

Background: Children before the age of 18 years are highly vulnerable to certain life-threatening diseases such as cancer, which is predicted from statistical evidence in the literature reviewed and in need of chemotherapy medications with side effects.
Objectives: This study aimed to assess parents’ perception of children with cancer complaining of gastrointestinal side effects of chemotherapy.
Materials and Methods: A cross-sectional study was conducted during the period (from October 4, 2023, to January 26, 2024) at Al-Furat Al-Awsat Oncology Hospital in Al-Najaf Al-Ashraf City using a questionnaire structured for objective achievement. The questionnaire consisted of a demographic and clinical data section and the parents’ perception of the gastrointestinal side effects of chemotherapy.Statistical and inferential analyses were performed to examine the data. Data were collected from (113) participants who selected nonprobability (convenience) by the interview researcher.
Results: The study specified that mothers comprised the majority of the sample and their ages were between (41 and 50), while the sickest children were male and female. Loss of appetite and taste changes were the most effective gastrointestinal side effects of chemotherapy, and the overall perception of the parents was good.
Conclusions: This study demonstrated that most patients suffer from loss of appetite and taste change, and they have a good perception of this side effect. This result emphasizes the importance of providing sufficient information to parents about any side effects that could appear in a child after a chemotherapy session.
Comparative Study of Physico-Chemical Parameters and Zooplankton Bio Diversity Between Twolakes (Pathipaka and Chinnakodepaka) at Jayashankar Bhupal Pally District
Authors: Veena Polasani , Sridevi Boddireddy , Swapna Padidela
Published: February 2025

Water is essential for living organisms especially like Flora and Fauna. The presented study deals with comparative study of the periodic and aperiodic variations of Physico-chemical status of two lakes belongs of Pathipaka Lake and chinnakodepakaLake of Bhupal pally Jayashnkar District,in Telangana. Both lakes having natural freshwater body. Different data are collected and observed through various field trips. A comparative study of the periodic and aperiodic variations of the Physico-chemical status of two lakes were studied in year 2023-2024. Both the lakes are biotically affected by various anthropogenic activities. In the present study water characteristics of two lakes have been compared the water quality. Different Parameters like Temperature, pH, conductivity, COD, BOD and also Zooplankton diversity. Both lakes are suitable for Fish culture and they are not polluted ponds
Studies of Various Genetic and Epigenetic Factors Influenced an Early Puberty in Females
Authors: Veena Polasani , Sridevi Boddireddy , Swapna Padidela
Published: February 2025

The age of female puberty appears to have decreased in  recently as child health and nutrition have improved and obesity has become more prevalent. Also, environmental contaminants, particularly endocrine disruptors, may also play a role in lowering the age of puberty. Puberty at an early age increases the risk of stress, poor school performance, teen pregnancy, eating disorders, substance abuse, and a variety of health issues which may appear later in life including breast cancer and heart disease. Risk factors related to early puberty include genetics, race, maternal weight gain, premature or low birth weight, fatherlessness, environmental contaminants, obesity, and race. Maintenance or achievement of healthy weight, regular exercise, and a fiber-rich diet may delay the onset of early puberty. As the number of girls entering premature puberty increases, there are numerous risks, both physical and emotional. Health educators need to explore ways to help reduce the incidence and prevalence of obesity and address other modifiable risk factors.
Androgen Receptors and Keloid Treatment in Children: Insights on Androgen Insensitivity Syndrome
Authors: Jafarli Ilhama , John Brejeetta , Syed Mobin , Huseynova Irada
Published: February 2025

Background: Keloids can form from an overgrowth of skin fibroblasts where the scar tissue extends beyond the initial boundaries of the injury; they are benign lesions. Studies indicated that androgens could influence these fibroblasts to cause excessive collagen deposition causing keloid formation (1). We aim to look at surgical and non-surgical management of keloids in children and to explore pain management during keloid treatment in children.
Methods: A systematic search was conducted using Medline, Embase, PubMed and Cochrane Library looking into the different keloid treatments used in children. As there were limited studies looking into pain management in children, an exclusion was made to investigate adult (age>18 years) studies. We hypothesized that the use of surgical and adjuvant therapy is better for steroid treatment.
Results: Out of the 33 abstracts, 21 articles fit the inclusion criteria.
Conclusion: Non-surgical treatments such as intralesional triamcinolone acetonide (TCA) and Botulinum toxin Type A reduced the volume of keloids up to around 80%. A combination therapy is safer with fewer side effects in the paediatric population. A study has also suggested the use of anti-androgenic treatment such as Finasteride or Combined Oral Contraceptives can help to reduce inflammation within the skin and provide ‘long-term’ health benefits to those predisposed to keloids. Surgical and non- surgical treatment
(including anti-androgenic treatment) may be used in those who develop keloids after
gender affirming surgeries in those with conditions such as Androgen Insensitivity Syndrome (2). Further studies are required to understand the multimodal therapy that can be used to treat keloids in children.