bluuebunny/crossref_metadata_2025 huggingface dataset:
A description of the first open-source community release of MISTRA-v9.0: a 0D/1D atmospheric boundary layer chemistry model
Authors: Bock Josué , Kaiser Jan , Thomas Max , Bott Andreas , von Glasow Roland
Published: July 2022

Abstract. We present MISTRA-v9.0, a one-dimensional (1D) and box (0D) atmospheric chemistry model. The model includes a detailed particle description with regards to the microphysics, gas–particle interactions, and liquid-phase chemistry within particles.
Version 9.0 (v9.0) is the first release of MISTRA as an open-source community model.
A major review of the code has been performed along with this public version release to improve the user friendliness and platform independence of the model. The purpose of this public release is to maximise the benefit of MISTRA to the community by making the model freely available and easier to use and develop.
This paper presents a thorough description of the model characteristics and components.
We show some examples of simulations reproducing previous studies with MISTRA, finding that v9.0 is consistent with previous versions.
SUHMO: an AMR SUbglacial Hydrology MOdel v1.0
Authors: Felden Anne M. , Martin Daniel F. , Ng Esmond G.
Published: July 2022

Abstract. Water ﬂowing under ice sheets and glaciers can have a strong inﬂuence on ice dynamics, particularly through pressure changes, suggesting that a comprehensive ice sheet model should include the effect of basal hydrology. Modeling subglacial hydrology remains a challenge however, mainly due to the range of spatial and temporal scales involved - from subglacial channels to vast subglacial lakes. Additionally, networks of subglacial drainage channels dynamically evolve over time. To address some of these challenges, we have developed an Adaptive Mesh Reﬁnement (AMR) model based on the Chombo software framework. We extend the model proposed by Sommers et al. (2018) with a few changes to accommodate the transition from unresolved to resolved ﬂow features. We handle the strong nonlinearities present in the equations by resorting to an efﬁcient nonlinear Full Approximation Scheme multigrid (FAS-MG) algorithm. We outline the details of the algorithm and present convergence analysis results demonstrating its effectiveness. Additionally, we present results validating our approach, using test cases from the Subglacial Hydrology Model Intercomparison Project (SHMIP) (de Fleurian et al., 2018). We ﬁnish by presenting a more complex AMR test case and discuss the effective pressure distribution as the spatial resolution increases.
Inter- and intra-event rainfall partitioning dynamics of two typical xerophytic shrubs in the Loess Plateau of China
Authors: An Jinxia , Gao Guangyao , Yuan Chuan , Pinos Juan , Fu Bojie
Published: July 2022

Abstract. Rainfall is known as the main water replenishment in
dryland ecosystems, and rainfall partitioning by vegetation reshapes the
spatial and temporal distribution patterns of rainwater entry into the soil.
The dynamics of rainfall partitioning have been extensively studied at the
inter-event scale, yet very few studies have explored its finer intra-event
dynamics and the relating driving factors for shrubs. Here, we conducted a
concurrent in-depth investigation of all rainfall partitioning components at inter- and intra-event scales for two typical xerophytic shrubs (Caragana korshinskii and Salix psammophila) in
the Liudaogou catchment of the Loess Plateau, China. The event throughfall
(TF), stemflow (SF), and interception loss (IC), and their temporal
variations within the rainfall event, as well as the meteorological factors
and vegetation characteristics, were systematically measured during the
2014–2015 rainy seasons. Our results showed that C. korshinskii had significantly higher
SF percentage (9.2 %) and lower IC percentage (21.4 %) compared to S. psammophila
(3.8 % and 29.5 %, respectively), but their TF percentages were not
significantly different (69.4 % vs. 66.7 %). At the intra-event scale,
TF and SF of S. psammophila were initiated (0.1 vs. 0.3 h and 0.7 vs. 0.8 h) and peaked
(1.8 vs. 2.0 h and 2.1 vs. 2.2 h) more quickly, and TF of S. psammophila lasted longer
(5.2 vs. 4.8 h) and delivered more intensely (4.3 vs. 3.8 mm h−1), whereas SF of C. korshinskii lasted longer (4.6 vs. 4.1 h) and delivered more
intensely (753.8 vs. 471.2 mm h−1). For both shrubs,
rainfall amount was the most significant factor influencing inter-event
rainfall partitioning, and rainfall intensity and duration controlled the
intra-event TF and SF variables. The C. korshinskii with larger branch angle, more small
branches, and smaller canopy area, has an advantage over S. psammophila to produce SF more
efficiently. The S. psammophila has lower canopy water storage capacity to generate
and peak TF and SF earlier, and it has larger aboveground
biomass and total canopy water storage of individual plants to produce higher
IC compared to C. korshinskii. These findings contribute to the fine
characterization of shrub-dominated ecohydrological processes, and improve
the accuracy of water balance estimation in dryland ecosystems.
The characteristics of the 2022 Tonga volcanic tsunami in the Pacific Ocean
Authors: Hu Gui , Li Linlin , Ren Zhiyuan , Zhang Kan
Published: July 2022

Abstract. On 15th January 2022, an exceptional eruption of Hunga Tonga–Hunga Ha’apai volcano generated atmospheric and tsunami waves that were widely observed at oceans globally, gaining a remarkable attention to scientists in related fields. The tsunamigenic mechanism of this rare event remains an enigmatic due to its complexity and lacking of direct underwater observations. Here, to explore the tsunamigenic mechanisms of this volcanic tsunami event and its hydrodynamic processes in the Pacific Ocean, we conduct tsunami waveform and spectral analyses of the waveform recordings at 116 coastal gauges and 38 deep-ocean buoys across the Pacific Ocean. Combined with the constraints of some representative barometers, we obtain the plausible tsunamigenic origins during the volcano activity. We identify four distinct tsunami wave components generated by air-sea coupling and seafloor crustal deformation. Those tsunami components are differentiated by their different propagating speeds or period bands. The first-arriving tsunami component with ~80–100 min period was from shock waves spreading at a velocity of ~1000 m/s in the vicinity of the eruption. The second component with extraordinary tsunami amplitude in deep sea was from Lamb waves. The Lamb wave with ~30–40 min period radically propagated outward from the eruption site with spatially decreasing propagation velocities from ~340 m/s to ~315m/s. The third component with ~10–30 min period was probably from some atmospheric gravity wave modes propagating faster than 200 m/s but slower than Lamb waves. The last component with ~3–5 min period originated from partial caldera collapse with dimension of ~0.8–1.8 km. Surprisingly, the 2022 Tonga volcanic tsunami produced long oscillation in the Pacific Ocean which is comparable with those of the 2011 Tohoku tsunami. We point out that the long oscillation is not only associated with the resonance effect with the atmospheric acoustic-gravity waves, but more importantly the interactions with local bathymetry. This rare event also calls for more attention to the tsunami hazards produced by atypical tsunamigenic source, e.g., volcanic eruption.
Augmentation of WRF-Hydro to simulate overland-flow- and streamflow-generated debris flow susceptibility in burn scars
Authors: Li Chuxuan , Handwerger Alexander L. , Wang Jiali , Yu Wei , Li Xiang , Finnegan Noah J. , Xie Yingying , Buscarnera Giuseppe , Horton Daniel E.
Published: July 2022

Abstract. In steep wildfire-burned terrains, intense rainfall can produce large runoff that can trigger highly destructive debris flows. However, the ability
to accurately characterize and forecast debris flow susceptibility in burned terrains using physics-based tools remains limited. Here, we augment
the Weather Research and Forecasting Hydrological modeling system (WRF-Hydro) to simulate both overland and channelized flows and assess postfire
debris flow susceptibility over a regional domain. We perform hindcast simulations using high-resolution weather-radar-derived precipitation and
reanalysis data to drive non-burned baseline and burn scar sensitivity experiments. Our simulations focus on January 2021 when an atmospheric river
triggered numerous debris flows within a wildfire burn scar in Big Sur – one of which destroyed California's famous Highway 1. Compared to the
baseline, our burn scar simulation yields dramatic increases in total and peak discharge and shorter lags between rainfall onset and peak
discharge, consistent with streamflow observations at nearby US Geological Survey (USGS) streamflow gage sites. For the 404 catchments located in
the simulated burn scar area, median catchment-area-normalized peak discharge increases by ∼ 450 % compared to the baseline. Catchments
with anomalously high catchment-area-normalized peak discharge correspond well with post-event field-based and remotely sensed debris flow
observations. We suggest that our regional postfire debris flow susceptibility analysis demonstrates WRF-Hydro as a compelling new physics-based
tool whose utility could be further extended via coupling to sediment erosion and transport models and/or ensemble-based operational weather
forecasts. Given the high-fidelity performance of our augmented version of WRF-Hydro, as well as its potential usage in probabilistic hazard
forecasts, we argue for its continued development and application in postfire hydrologic and natural hazard assessments.
High-resolution subglacial topography around Dome Fuji, Antarctica, based on ground-based radar surveys over 30 years
Authors: Tsutaki Shun , Fujita Shuji , Kawamura Kenji , Abe-Ouchi Ayako , Fukui Kotaro , Motoyama Hideaki , Hoshina Yu , Nakazawa Fumio , Obase Takashi , Ohno Hiroshi , Oyabu Ikumi , Saito Fuyuki , Sugiura Konosuke , Suzuki Toshitaka
Published: July 2022

Abstract. The retrieval of continuous ice core records of more than 1 Myr is an important challenge in palaeo-climatology. For identifying suitable sites for drilling such ice, knowledge of the subglacial topography and englacial layering is crucial. For this purpose, extensive ground-based ice radar surveys were carried out over Dome Fuji in the East Antarctic plateau during the 2017/18 and 2018/19 austral summers by the Japanese Antarctic Research Expedition, on the basis of ground-based radar surveys conducted over the previous ∼ 30 years. High-gain Yagi antennae were used to improve the antenna beam directivity, thereby significantly decreasing hyperbolic features of unfocused along-track diffraction hyperbolae in the echoes from mountainous ice–bedrock interfaces. We combined the new ice thickness data with the previous ground-based data, recorded since the 1980s, to generate an accurate high-spatial-resolution (up to 0.5 km between survey lines) ice thickness map. This map revealed a complex landscape composed of networks of subglacial valleys and highlands. Based on the new map, we examined the roughness of the ice–bed interface, the bed surface slope, the driving stress of ice and the subglacial hydrological condition. These new products and analyses set substantial constraints on identifying possible locations for new drilling. In addition, our map was compared with a few bed maps compiled by earlier independent efforts based on airborne radar data to examine the difference in features between datasets. Our analysis suggests that widely available bed topography products should be validated with in situ observations where possible.
Covid-19 salgını sürecindeki uzaktan eğitim modeline yönelik sosyal hizmet öğrencilerinin görüşleri
Authors: AYDEMİR İshak , ÜNAL Vehbi , GÖNÜLTAŞ Miraç Burak , ÖNGÖREN Bülent , KURUÇAY Nermin
Published: July 2022

Bu çalışmanın amacı, Covid-19 Pandemi sürecinde başlatılan zorunlu uzaktan eğitim modelinin işleyişi, uygunluğu, etkililiği, verimliliği ve uygulama temelli bir meslek olan sosyal hizmet derslerinin bu şekilde sunulmasının uygunluğu konusunda sosyal hizmet öğrencilerinin görüşlerinin belirlenmesidir. Bu çalışmada, genel tarama modeli esas alınmıştır. Çalışmaya 824 öğrenci katılım sağlamıştır. Covid-19 pandemisi nedeniyle katılımcılarla yüz yüze görüşme olanağı olmadığından e-anket yöntemi kullanılarak veriler toplanmıştır. Sosyal hizmet öğrencilerinin %77,5’i uzaktan eğitimin uygulamalı derslerinin etkili verilmesini olumsuz etkilediğini; %93,2’i örgün eğitimin uzaktan eğitim modelinden daha verimli olduğunu; %78,1’i uzaktan eğitimin yüz yüze eğitimin sağladığı olanakları sunamadığını; %80,6’sı uzaktan eğitimin uygulamalı dersleri öğrenmeyi kısıtladığını; %76,2’si uzaktan eğitimin yaşam stiline uygun bulmamakta; %92.3’ü uzaktan eğitimin öğrenciyi daha aktif hale getirmediğini; %74,8’i uzaktan eğitim ihtiyaç duyduğu eğitimler için uygun bir alternatif olarak görmediğini; %85’i eğitimimin en iyi şekilde gerçekleşmesi için yüz yüze etkileşimin gerekli olduğuna inanmakta; %28,2’i uzaktan eğitim gereksiz bulmakta, %50’si gerekli bulmakta; %41,7’si uzaktan eğitimi etkisiz bir eğitim modeli olarak görmekte, %21,8’i kararsız ve %36,4’ü ise etkili bir eğitim modeli olarak görmekte; %76,5’i uzaktan eğitim öğrencilerin sosyalleşme gereksinimlerini engellediğini; %75’i uzaktan eğitimde öğrencinin pasif kaldığını; %58,5’i uzaktan öğretimin gelecekte yüz yüze eğitimden daha çok tercih edileceğini düşünmemektedir.
Pandemi dönemi acil uzaktan eğitim uygulamalarında K12 düzeyinde öğrenme kayıplarının incelenmesi
Authors: ÖZGÜRDEN Selma , OKUR Muhammet Recep
Published: July 2022

Dünya çapında milyonlarca öğrenciyi etkileyen Covid-19 un, eğitim-öğretim üzerinde olumsuz etkileri olduğu gözlemlenmiştir. Bu nedenle Covid-19 pandemisi süresince uygulanan acil uzaktan eğitimin K12 düzeyinde öğrenme kayıplarını incelemek ve yaşanan öğrenme kayıplarına çözüm aramak bu araştırmanın amacını oluşturmaktadır. Böylece yapılan bu araştırma ile uzaktan eğitim sürecinin öğrenme üzerindeki olumlu etkilerini arttırmak hedeflenmiştir.

Bu hedef doğrultusunda öğrenme kayıplarını tespit etmek için nitel araştırma yöntemi olan case study deseninden yararlanılmıştır. Sınıf öğretmenleri ile yapılan görüşmelerde, pandemi dönemi K12 düzeyi acil uzaktan eğitim uygulamalarında daha çok sosyal öğrenme olmakla birlikte tüm dersler bazında kazanım eksikliği yaşandığı, teknoloji ve internet sorunu, ebeveyn desteğinin olmaması ve fiziksel uzaklığın öğrenme sürecini olumsuz etkilediği bulgular ile tespit edilmiştir. Ailelerin ve öğretmenlerin yaşanan öğrenme kaybının telafisi hususunda yapabilecekleri tartışılmış ve önerilerde bulunulmuştur.
THE RELATIONSHIP OF AGE AND OCCUPATION OF PREGNANT MOTHERS WITH COMPLIANCE IN DOING COVERAGE OF K4 ANTENATAL CARE AT BPM MARMINA FOUR LAWANG IN 2020
Authors: Joyce Angela Yunica  , Poppy Septiana
Published: July 2022

Antenatal care is a haelth service by a professional to a women during their pregnancydone according to the standart of antenatal care service. Pregnant women visit recommended to health service is once in first three semester, once in second three semester, and at least twice in third three semester. This research aimed to find out the relation of pregnant women’s age and jobs with the obedience of doing K4 antenatal care scope at BPM Marmina Empat Lawang in 2020. The population of this reseach was 146 third semester pregnant women doing antenatal care at BPM Marmina. Third semester pregnant women who obeyed were less (22,6%) than those who didnt (77,4%). Third semester pregnancy of low risky aged women were 74,7%, it was less than those who were in high risky pregnance (25,3%). Third semester pregnancy of working women (34,2%), it was less than those who didnt (65,8%). By the result of chi-square test gotten was the relation between pregnant women’s age and the obedience of doing K4 antenatal care scope at BPM Marmina Empat Lawang in 2020 was p-value 0,008. It showed that there was a meaningful relation betweenpregnant women’s age with the obedience of doing K4 antenatal care scope at BPM Marmina Empat Lawang in 2020. By chi-square test that the relation between pregnant women’s job and the obedience of doing K4 antenatal care scope at BPM Marmina Empat Lawang in 2020 was gotten p-value 0,001. It showed thar there was a meaningful relation between pregnant women’s job and tje obedience of doing K4 antenatal care scope at BPM Marmina Empat Lawang in 2020. BPM Marmina Empat Lawang was hoped to be active at ANC service in order pregnant women obey more to examine their pregnancy.
PENGARUH AROMATERAPI DAUN SEMANGGI TERHADAP INTENSITAS NYERI PUNGGUNG PENYADAP KARET DI DESA TANJUNG AUR
Authors: Mujahidin
Published: July 2022

Kegiatan menyadap getah karet merupakan suatu rutinitas yang telah lama dilakukan oleh warga Desa Tanjung Aur secara turun temurun. Aktivitas menyadap getah karet selama ini masih dilakukan secara manual dan bertumpu pada kekuatan tangan dan punggung dalam melakukannya. Permasalahan Kesehatan yang biasanya sering terjadi pada penyadap karet ini adalah permasalahan nyeri punggung. Penelitian ini bertujuan untuk melihat bagaimana pengaruh dari aromaterapi daun semanggi terhadap intensitas nyeri punggung penyadap karet. Sampel dalam penelitian ini adalah penyadap karet yang terdapat di Desa Tanjung Aur berjumlah 20 orang yang dipilih menggunakan tehnik purposive sampling serta memenuhi beberapa kriteria. Penelitian ini merupakan penelitian quasy eksperimental one grup pre test post test design. Penelitian ini dilaksanakan pada bulan April - Mei 2022 bertempat di Desa Tanjung Aur Kecamatan Jejawi Kabupaten Ogan Komering Ilir Sumatera Selatan. Hasil analisis dengan menggunakan uji wilcoxone didapatkan nilai p < 0.002 yang selanjutnya disimpulkan bahwa terdapat pengaruh yang cukup signifikan penggunaan aromaterapi daun semanggi terhadap intensitas nyeri punggung penyadap karet di Desa Tanjung Aur Kecamatan Jejawi Kabupaten Ogan Komering Ilir Provinsi Sumatera Selatan.
HUBUNGAN KARAKTERISTIK PERAWAT DENGAN RESTRAIN PASIEN GADUH GELISAH DI INSTALASI GAWAT DARURAT RUMAH SAKIT ERNALDI BAHAR PROVINSI SUMATERA SELATAN
Authors: Elma Henda  , Oscar Ari Wiryansyah
Published: July 2022

Banyak tantangan yang harus dihadapi perawat ketika harus menangani pasien gaduh gelisah dengan restrain, sebab sewaktu-waktu pasien bisa bertindak agresif dan bisa membahayakan lingkungannya. Usia, tingkat pendidikan dan masa kerja perawat diduga berhubungan dengan restrain pasien gaduh gelisah. Desain penelitian ini adalah kuantitatif menggunakan metode survey analitik secara cross sectional. Sampel penelitian ini adalah seluruh perawat yang bertugas di IGD Rumah Sakit Ernaldi Bahar sebanyak 30 orang. Analisis data penelitian ini dilakukan secara univariat dan bivariat. Disimpulkan bahwa ada hubungan antara usia perawat dengan restrain pasien gaduh gelisah, dengan p value = 0,028 ; ada hubungan antara pendidikan perawat dengan restrain pasien gaduh gelisah, dengan p value = 0,015 ; ada hubungan antara masa kerja perawat dengan restrain pasien gaduh gelisah, dengan p value = 0,023. Disarankan agar pihak manajemen Rumah Sakit Ernaldi Bahar memberikan pelatihan aplikasi dalam SOP, mengadakan seminar serta mengevaluasi tindakan pemasangan restrain.
Nobleza, respeto y horizontalidad como fundamentación moral de la comunidad en F. Nietzsche
Authors: Vázquez Manzano Francisco
Published: July 2022

En este trabajo llevaré a cabo una labor hermenéutica sobre el pensamiento político de Friedrich Nietzsche, ampliamente denostado en la recepción temprana de su obra, pero actualmente revitalizado a la luz de nuevos estudios que muestran la unión existente entre la reflexión moral del alemán y su propuesta para un modelo de comunidad. Nietzsche nos servirá de pretexto para alcanzar una caracterización de la comunidad como «comunidad agónica», sostenida sobre el litigio permanente y el reconocimiento recíprocamente afirmante del otro. La caracterización que propondremos de la comunidad busca alejar todo rasgo individualista de la misma mostrando toda obstinación individualista como signo de impotencia y resentimiento.
The unity of crime forms in national and foreign criminal doctrine: features and objections
Authors:   Moldova State University, Papanaga Cristina
Published: July 2022

The article analyzes the unity of crime forms, encountered in national and foreign criminal doctrine. These authors’ works explain in comparative plan the legislative formulation of unity crime, as well as to solve some collisions that appeared in practice, regarding the qualification of different unity crime forms: prolonged offense, continuous crime, complex crime, deviated crime, progressive crime, habit crime, so, using the deductive analysis in this sense. The purpose of this study is to improve the legislative framework of unity crime’s institution, together with the punishments, applicable to each unity of crime’s form.
Production of anthrax isolate, its registration and studу of biological properties in accordance with biological safety requirements
Authors: Artemeva E. A. , Melnikova L. A. , Rodionov A. P. , Hammadov N. I.
Published: July 2022

State collections of pathogenic microorganisms play an important role in ensuring the biological safety of Russian Federation. They carry out storage and comprehensive study of collection strains of microorganisms using modern methods. The collection fund is formed due to the deposition and receipt of strains upon request from other collections, also those isolated during the indication, diagnostic and monitoring studies of natural ecosystems, and in the course of experimental activities. The purpose of this work was to study the biological properties of the anthrax pathogen isolate obtained in the established manner, issue a passport for it and include it in the list of collection strains for further storage. An isolate of anthrax pathogen isolated during diagnostic studies from pigs in the city of Sengiley, Ulyanovsk region. The results of the study showed that the biological properties of the isolate are identical to the virulent strain “Ch-7” of the anthrax pathogen. As a result, the isolate was assigned to the genus Bacillus, species anthracis and designated as the strain “Sengiley”, with the introduction of these data necessary journals. The work carried out to study the biological properties of anthrax isolate showed a strict compliance with biological safety requirements with the execution of all necessary documents in accordance with regulatory documents.
The content of immunoglobulins in the blood serum of mother cows with genital mycoplasmosis and calves born from them
Authors: Vasiliev R. M.
Published: July 2022

The state of the immune system of newborn animals largely determines their further development, morbidity, and productive qualities. Various diseases of pregnant animals to a certain extent affect the body of the fetus, this is especially true if the disease is characterized by an erased clinical picture and it is difficult to diagnose it in a timely manner. One of these diseases is genital mycoplasmosis of cattle, which is widespread both in our country and abroad. Despite this, many aspects of the pathogenesis of genital mycoplasmosis remain poorly understood, especially the state of the immune system. A study was made of the content of immunoglobulin classes in healthy dry cows and cows with genital mycoplasmosis, as well as in calves born by them. The results showed a significant decrease in the level of immunoglobulins and a redistribution of their classes in cows with genital mycoplasmosis. Changes of a similar nature, but more pronounced, were also noted in calves born from these cows. Studies show that pregnant cows with genital mycoplasmosis develop an immunodeficiency state, characterized by a decrease in the total amount of immunoglobulins, a significant decrease in the level of Ig G and an increase in the concentration of Ig A. A similar immunodeficiency state was observed in calves obtained from these cows. The noted changes will be useful for the development of rational therapy for genital mycoplasmosis in cows.
Features of the growth and formation of the physique of nenets reindeer from birth to puberty
Authors: Yuzhakov A. A. , Laishev K. A.
Published: July 2022

In the Yamalo-Nenets Autonomous District were studied 169 heads of Nenets deer from birth to 18 months of age The maximum rate of weight gain of live weight of calves is observed in the first 6 months of postnatal development and has sexual differentiation: in males it was 52.5, in females – 46.5 kg. From 6 to 12 months of age, which falls during the wintering period, in the studied groups of deer there was a drop in absolute indicators of live weight gain to minus values: males -5.3 kg, females -1.7 kg. In the period from 12 to 18 months of age, the absolute growth rates of males and females turned out to be equal. The rate of linear growth and the formation of the physique of young deer in the period from birth to 6 months of age, no significant difference between males and females was found either visually or instrumentally.. During the first wintering period, an increase in absolute value was observed by measurements associated with the growth of the skeleton: height at the withers, height at the elbow, head length, chest depth, oblique length of the butt. The age period from 12 to 18 months is characterized by a significant increase in linear body sizes in the studied deer, but the difference in almost all measurements did not exceed 4%. A comparison of 10 indices of physique in animals showed that at 6 and 18 months of age, the main proportions of the physique are close, which indicates a high rate of formation of the physique in young domestic reindeer. A comparison of the physique indices revealed no signs of sexual dimorphism for any of them, except for the pelvic index, which was higher in females at all age periods and the broadbodied index at 18 months of age.
Correlative relations of malnutrition and redox homeostasis disorders in allergic enteropathy in dogs with severe gi syndrome
Authors: Ushakova T. M. , Derezina T. N.
Published: July 2022

Malnutrition syndrome is widespread in allergic enteropathy in dogs, causing a violation of absorption and transport of nutrient substrates in the intestinal mucosa, which serves as a trigger for subsequent metabolic changes in the gastrointestinal system, affecting hepatocytes through the activation of lipid peroxidation processes and the development of shifts in the redex system. homeostasis. As a result of biochemical and morphological studies of the blood of sick animals with allergic enteropathy with severe gastrointestinal syndrome, a violation of metabolic processes was established (T-Pro - 59.46±0.32 g/l and 63.34±0.53 g/l; ALB - 19.71±0.64 g/l and 18.56±0.50 g/l; GLB - 39.75±0.82 g/l and 44.78±0.96 g/l; A/G - 0.49±0.06 and 0.41±0.08; RBC - 5.85±0.17×1012/l and 5.67±0.16×1012/l; Na - 134.50±6.10 mmol/l and 130.80±5.97 mmol/l, K - 3.43±0.10 mmol/l and 3.40±0.09 mmol/l, Ca - 2.15±0.07 mmol/l and 2.13±0.06 mmol/l), redox homeostasis (ALT - 108.95±11.00 U/l and 115.73±9.39 U/l; AST - 62.90±6.05 U/l and 60.30±5.80 U/l; ALP - 196.05±19.20 U/l and 210.20±23.91U/l) due to activation of lipid peroxidation processes (MDA - 23.10±1.06 µmol/ml and 24.25±1.40 µmol/ml; DK - 1.08±0.15 uA/ml and 1.15±0.09 uA/ml) and antioxidant potential depletion (CT - 0.54±0.02 Bach units and 0.55±0.03 Bach units; SOD - 18.23±1.59 EU/mg protein per minute and 19.98±1.91 EU/mg protein per minute; GSH-Px - 26.69±2.46 µmol/ml and 28.31±3.02 µmol/ml; Vitamin A - 0.66±0.05 mcg/ml and 0.59±0.03 mcg/m; Vitamin E - 8.49±0.90 mcg/ml and 7.87±0.98 mcg/ml). The presence of direct correlations between the level of trophological disorders due to the development of intestinal malabsorption syndrome and the degree of redox homeostasis disorders was revealed.
Features of the histological organization of pancreatic tissues on the example of a domestic bull
Authors: Barteneva Yu. Yu. , Prusakov A. V. , Zelenevsky N. V.
Published: July 2022

The aim of the study was to establish the features of the histological organization of pancreatic tissues on the example of a domestic bull. For its implementation, pancreatic tissue samples of five sexually mature one-year-old cows of a black-and-white breed obtained by biopsy were used. The selected material was fixed in a 10.0% solution of neutral formalin for a day, after which it was poured into paraffin according to the generally accepted method. Histological sections were made from the obtained blocks, which were stained with hematoxylin and eosin, according to Van Gieson and trichrome according to Mosson. It has been established that the studied organ in the studied animals belongs to complex alveolartubular glands. From the outside, it is covered with a delicate connective tissue capsule, giving rise to connective tissue strands (trabeculae) passing between its lobules. Vascular elements, nerve trunks and excretory ducts are identified as part of these structures. The gland itself, in accordance with its function, includes two parts – endocrine and exocrine. The terminal sections of its exocrine part are represented by pancreatic acinuses. As part of the latter, two departments can be distinguished - secretory (formed by serous endocrinocytes) and ductal (formed by epithelial cells (centroacinous) of the initial sections of the insertion excretory ducts). The secretory department of the acinus includes from seven to eleven cells having a pyramidal shape. They contain one welldeveloped basophilic rounded nucleus, and two zones are revealed in their cytoplasm. The basal – homogeneous – zone has a basophilic color and is located in the basal part of the cell. The apical – zymogenic (apical) zone contains secret granules and is colored oxyphilically. The endocrine part of the gland is represented by pancreatic islets (islets of Langerhans) formed by strands of closely interconnected endocrine cells (isulocytes) surrounded by abundant capillary loops forming branched networks inside the islet. Insulocytes are small cells having a polygonal shape with a poorly defined border. In their composition, one rounded or oval nucleus is revealed, containing evenly distributed small-smiley chromatin.
Application of conjugate based on colloidal gold for express diagnostics of rabies in dot immunoanalysis
Authors: Akhmadeev R. M. , Galeeva A. G. , Arslanova A. F. , Efimova M. A. , Nasyrov Sh. M. , Kashevarov G. S. , Yarullin A. I. , Salnikov V. V.
Published: July 2022

The aim of the research was to develop a direct dot-immunoassay on a nitrocellulose membrane (NCM) using a conjugate based on colloidal gold for the qualitative determination of the presence of rabies virus antigen in pathological material. As the test samples, we used brain samples of various animal species, which were positive during the initial study by methods of fluorescent antibodies: foxes and mice. IFA and indirect ELISA carried out using diagnostic kits manufactured at the Federal Center for Toxicological, Radiation and Biological Safety. The materials present the results of primary laboratory tests of the test system for the indication of rabies antigen based on direct dotimmunoassay (DIA) 81 samples of pathological material, the brain of various animal species. It was shown that DIA has 100% specificity, and its optical signals correlate with the results of indirect ELISA. The proposed DIA method, in addition to independent application, can also serve as a basis for the design of test systems based on immunochemical analysis.
Influence of vaccination with the immunocomplex vaccine from the VNIVIP strain on IL-6 gene expression and representation of opportunitical microorganisms in the intestine of laying hen
Authors: Tarlavin N. V. , Veretennikov V. V. , Javadov E. D. , Kozyrenko O. V. , Kraskov D. A.
Published: July 2022

The immunocomplex vaccine against infectious bursal disease from the VNIVIP strain has strong immunogenic properties, including active expression of the IL-6 cytokine synthesis genes in the tissues of the bursa of Fabricius and cecum. This phenomenon stimulates a local non-specific immune response, resulting in a reduction in the representation of pathogenic and opportunistic microorganisms in the intestines of chickens. As a result of the studies, it was found that the relative expression in the tissues of the caecum of the intestines of chickens of the Loman White cross reached a 2.7-fold excess over the control level, and the relative expression in the tissues of the Fabricius bag - 15.6-fold excess over the control level. The relative content of bacteria of the Escherichia coli group, as sanitary indicative microorganisms, decreased by 4 times under the influence of the vaccine (from 0.253% in the control group to 0.064% in the vaccinated group). The variety of staphylococci under the influence of the vaccine was also reduced, and only unidentifiable representatives of the genus Staphylococcus were found in the vaccinated group.
Physiological status of the BLV-infected cows offspring under dyspeptic manifestations correction
Authors: Krasnikova E. S. , Radionov R. V. , Krasnikov A. V.
Published: July 2022

The BLV-infected cows’ offspring are at risk due to a decrease in their viability and productivity indicators. The purpose of the studies is a comparative analysis of hematological parameters and indicators of body weight gain in obtained from immunocompromised cows calves when correcting their clinical status using the composition we have developed (patent No 2646831) and a broadspectrum antibiotic. According to our data, calves from BLV-infected mothers were born with a body weight of 6-7% less than calves from intact cows. With the correction of dyspeptic manifestations in calves by the proposed method, the average daily gain in animals remained at the level with intact ones (630-660 g / day), and when using an antibiotic, it was 300-500 g per day. Hematological studies have shown that with clinical manifestations of dyspepsia in neonatal calves, hypovolemia and pronounced leukocytosis are noted in the blood, the signs of which decrease by the 12th day of life during therapy. The glucose of blood serum in calves with dyspeptic syndrome was slightly reduced on the first day. There was a change in the blood electrolytes ratio, a decrease in total blood protein and albumin content, compared to intact animals. Thus, our studies have shown that when correcting dyspepsia in neonatal calves from immunocompromised cows using the composition we have developed, the body weight gain retained, which was due to the rapid normalization of the homeostasis in animals.
The state of gluconeogenic liver function of white rats under the influence of a nanocomposite aqueous solution of fullerene С60
Authors: Alekseev A. A. , Pudovkin N. A. , Salautin V. V. , Klyukin S. D.
Published: July 2022

Biocompatible nanoparticles attract the attention of researchers as a means of correcting a wide range of diseases. The carbonbased nanostructure, fullerene C60, is one of the most promising compounds. However, the use of compounds based on fullerene nanoparticles remains limited. Therefore, the development of domestic innovative medicinal compounds based on fullerenecontaining nanoparticles is one of the priority areas of veterinary medicine. The research was carried out in the laboratory of the Department of "Morphology, Pathology of Animals and Biology" of the Saratov State Agrarian University named after N.I. Vavilov. The first group served as a control. An aqueous solution of fullerene C60 was administered at a dose of 1 ml per (DV 5 mg / kg) 1 kg of body weight (group 2 animals). A compound based on an aqueous solution of fullerene C60 was also introduced, including an aqueous solution of fullerene C60, Lcarnosine and succinic acid in the following ratio of components, wt. / mg: an aqueous solution of fullerene C60 stabilized with pluronic F-127– - 5 ml (5 mg by DV), Lcarnosine -50 mg, succinic acid - 50 mg per 1 kg of body weight (group 3). The studied compounds were administered intramuscularly, once. Glycerin loading was carried out 24 hours after the introduction of the studied compounds. It was found that aqueous solutions of fullerene C60 have a distinct effect on carbohydrate metabolism in the body of white rats. The initial blood glucose level in animals of all groups turned out to be approximately at the same level, but the highest rate of gluconeogenesis was found in animals of group 2. As for the gluconeogenic function of the liver, in animals after the introduction of aqueous solutions of fullerene C60, the increase in newly formed glucose and the rate of gluconeogenesis significantly exceeded the control values. The results obtained indicate a failure in glucose metabolism after the introduction of aqueous solutions of fullerenes.
Evaluation of therapeutic and prophylactic effectiveness of levofloxacin in experimental colibacillosis of chickens with regard to infecting dose
Authors: Mazur A. D. , Skvortsov V. N. , Yurin D. V. , Gorbaneva A. S.
Published: July 2022

The goal of the present research was to investigate therapeutic and prophylactic effectiveness of levofloxacin following experimental challenge of chickens with varying doses of Escherichia сoli namely 1 minimum lethal dose (DLM) and 4 minimum lethal doses (DLM). We conducted two experiments on two-day-old Hisex Brown chickens. For the first experiment we used 6 groups of chicks (n = 25, in each group). The drug was administered via drinking water (with free access) 24 hours before the challenge. Chicks of Groups 1 to 4 received levofloxacin via drinking water at concentrations 50 mg/L, 100 mg/L, 200 mg/L and 300 mg/L for 5 days. Group 5 was control, Group 6 was intact. The chicks were challenged with 1.5 х 108 E. сoli bacterial cells per 0.5 mL (1 minimum lethal dose (DLM)) intraperitoneally. The second experiment was conducted similarly but the infecting dose was increased by 4 times (4 minimum lethal doses (DLM)).Administration of levofloxacin at concentration 300 mg/L both in the first experiment, when the infecting dose was 1 minimum lethal dose, and in the second experiment, when the infecting dose was 4 minimum lethal doses, proved that the drug has the same high therapeutic and prophylactic effectiveness of 96 %. Administration of the drug at concentration 200 mg/L showed 100 % effectiveness in the first experiment. But in the second experiment levofloxacin at the same concentration ensured survival of only 88 % of the challenged chicks. When the drug was administered at concentration 100 mg/L we observed reliable change in indices. Accordingly in the first experiment 88 % of the chicks survived. In the second experiment, when the infecting dose increased to 4 minimum lethal doses, only 52 % of the chicks survived. Administration of levofloxacin at concentration 50 mg/L did not show significant therapeutic effect.
A comprehensive approach to the diagnosis of breast neoplasms in domestic unproductive animals
Authors: Gorinsky V. I. , Salautin V. V. , Pudovkin N. A. , Klyukin S. D. , Salautina S. E.
Published: July 2022

The spread of oncological diseases is currently one of the main problems in both humanitarian and veterinary medicine. Despite the high achievements of domestic and foreign scientists of modern veterinary medicine in the field of diagnosis, treatment and prevention of oncological processes, the number of cancer-affected animals is quite large and continues to grow steadily. Therefore, improving the complex of diagnostic studies for neoplasms among dogs and cats is one of the priority areas of veterinary medicine. The research was conducted on the basis of the veterinary clinic of the Center for Animal Beauty and Health "Zoostyle" IP Gorinsky V.I. (Volgograd) and the Department of "Morphology, Pathology of Animals and Biology" of the Saratov State Agrarian University. In the period from 2018 to 2021, 244 patients, including 127 dogs and 117 cats, were examined by an oncologist at the veterinary clinic of the Zoostyle Center for Animal Beauty and Health.All the animals belonged to residents of the city of Volgograd. When an animal was admitted to the clinic for an oncological appointment, animals with any visual signs of a neoplasm in the projection of the breast were selected for research. As a result of the physical examination, based on the results of laboratory, X-ray and ultrasound examinations, MR tomography, it was found that breast tumors (OMJ) are more common among dogs and cats. In the population of dogs, OMH accounted for 33.8% (n=43) and 62.4% (n=73) of all cases of oncological pathology in cats. Depending on the gender, breast neoplasia was observed in females - 100%, in cats, females accounted for 89%, and males - 11%. The results obtained indicate that the introduction of a complex of modern high-tech diagnostic methods into veterinary oncology practice is a key element that significantly affects the prospects for providing specialized care and prognosis.
The Boosting Effect of Covid-19 Breakthrough in Digital Broadcasting
Authors: ASLAN Özgür , SADIÇ Faruk , KANBUR Yavuz
Published: July 2022

Since the first trials of a series of inventions leading to the invention of television, the medium has undergone continuous development and transformation and has taken its current form. Television continues to change today, with user needs and new effects in different communication technologies. In the light of these developments, digital broadcasting by experiencing convergence between internet and television; It gave birth to concepts such as Web TV, IPTV and Mobile TV. Especially widespread internet-connected devices over The Top Television (OTT TV) have contributed to the emergence of broadcasting. In this study, the journey from the historical development of television to digital broadcasting was discussed and the growth experienced by Netflix, especially during Covid-19, was mentioned as an example of OTT TV, which is popular worldwide. Semi-structured interviews were conducted with 12 people with four different sociocultural structures. Visualization opportunities were used to better understand the data and some of the remarks of the participants were included. Looking at the data obtained after the interview, it was observed that the Netflix subscription increased during the Covid-19 period and the time spent on the screen increased.
The Therapeutic Action of Queen of Herb (Ocimum tenuiflorum)
Authors: B. Marathe Sagar , Naitik Mali , Z. Shaikh Azam
Published: July 2022

This review paper purpose is the ‘Queen of herb’’ means holy basil/Tulsi is how to showing it Antimicrobial activity by using different type of method. This paper also study the pharmaceutical used of Tulsi and its Pharmacological activity of Tulsi like. Antimicrobial activity, Antifungal activity, Anti-inflammatory and Analgesic activity. It is main symbol of the Hindu region tradition this is plant having unique odor found in the semitropical and tropical country. In the world. This is plant mainly used for reducing the cough. Holy basil is ancient Hindu scriptures, tulsi occupies the supreme position among the herb so that it referred to as “MOTHER”. It has been used Ayurveda and siddha practices for it’s supposed treatment of diseases. It having medicinal her that belong to the mint family and is found in 150 different worldwide. Tulsi has been used in thousands of years in Ayurveda for its diverse healing properties special about this plant is apart from being considered holy Tulsi is also reserved as great healer.
Compartment Syndrome Secondary to Vascular Transection from a Knee Dislocation
Authors: Mirajkar Amber , Morales-Cruz Martin , Fusco Nicholas , Dub Larissa , Ganti Latha
Published: July 2022

Acute knee dislocation is a rare orthopedic injury with an incidence of <0.02% annually. The authors discuss a case involving a vascular injury sustained from a mechanical fall at home causing compartment syndrome. The case illustrates known complications associated with knee dislocations: vascular injury and compartment syndrome as well as the high suspicion needed in certain patient populations, such as Down’s syndrome. It highlights the importance of rapid diagnosis, a complete physical exam, and the need to involve consultants in a timely fashion. A high index of suspicion for vascular injury following trauma to the knee, regardless of the mechanism is imperative.
The ability and factors related with floor sitting after total hip arthroplasty with a posterolateral approach
Authors: Nawatthakul Anuchit , Hongnaparak Theerawit , Iamthanaporn Khanin , Yuenyongviwat Varah
Published: July 2022

Background

Prosthesis dislocation following total hip arthroplasty (THA) is one complication that affects treatment outcome and increases the cost of treatment. Currently, many surgeons prohibit patients from performing floor-based activities; however, these prohibitions might affect the lifestyle of a number of patients.

Objective

This study aimed to evaluate the ability of floor sitting after THA, and factors associated with this ability

Methods

This study was a retrospective cohort study, evaluating 240 patients who underwent THA with a posterolateral approach, in a single tertiary hospital. Patient demographic data, preoperative clinical data, prostheses type, and postoperative radiographic were extracted from the electronic medical records. Postoperative ability to perform floor sitting was evaluated at 6 months postoperatively.

Results

There were 52 patients (21.66%) who were able to sit on the floor postoperatively. Multivariate logistic regression analysis showed independent association between three factors with ability to sit on the floor after surgery: pre-operative external rotation range of motion (OR 1.03; 95% CI, 1.01-1.06; P = 0.01), pre-operative Harris Hip Scores (OR 1.05; 95% CI, 1.01-1.10; P = < 0.01), pre-operative ability to sit on the floor (OR 10.2; 95% CI, 3.65-28.5; P = < 0.01).

Conclusion

There were a number of patients who could sit on the floor after THA. However, there were factors which were associated with this ability. Hence, these results could be useful for adjusted patient preoperative expectations, and did not preclude all patients to perform floor activities.
Age over 50 does not predict results in anterior cruciate ligament reconstruction.
Authors: Corona Katia , Cerciello Simone , Vasso Michele , Toro Giuseppe , D'Ambrosi Riccardo , Pola Enrico , Ciolli Gianluca , Mercurio Michele , Schiavone Panni Alfredo
Published: July 2022

Introduction

Grown in the worldwide population of over 50 of age individuals who remain in good health and continue to engage in sports has led to an increase of anterior cruciate ligament (ACL) tears in this aged population. ACL reconstruction was reserved for young and active athletes, but seems to produce good outcomes also in over 50s.

Purpose

To compare the patient-reported functional scores, arthrometric outcomes, and complications of primary ACL reconstruction between older (>50 years) and younger (<50 years) patients.

Methods

A systematic review was performed on Pubmed, Scopus, Google Scholar and Cochrane library regarding studies that compared the clinical outcomes of ACLR between patients aged > 50 years and those aged < 50 years. The outcomes evaluated were knee functional outcomes, antero-posterior laxity and complications rate.

Results

This study included 5 retrospective cohort studies with a total of 645 patients (357 in the older 50 group and 288 in the younger group). All included studies reported significant improvements in clinical outcomes in both groups after ACL reconstruction. No significant differences were noted in terms of International Knee Documentation Committee (IKDC), Lysholm, Tegner scores and anteroposterior instability between the two groups (p = n.s.). Over 50 cohort seem to have an increased risk for complication rate when compared with the younger cohort (p= 0.0005).

Conclusion

ACL reconstruction in patients older than 50 years is a safe procedure with good results that are comparable to those of younger patients.

Study design

Systematic review and meta-analysis; Level of evidence, 3