bluuebunny/crossref_metadata_2025 huggingface dataset:
Massive production of Hemileia vastatrix uredospores for infection of Coffea arabica seedlings
Authors: Hernández-Amasifuen Angel David , Rivadeneyra-Chisquipama Lenin , Padilla-Dominguez Amner , Paredes-Espinosa Richard , Guerrero-Abad Juan Carlos , Torres-Flores Elías , Peláez-Rivera Jorge Luis , Carvajal-Vallejos Fernando Marcelo , Gutiérrez-Reynoso Dina Lida , Corazon-Guivin Mike Anderson
Published: July 2023

Coffee leaf rust (Hemileia vastatrix) is the most important disease in coffee crops around the world. Currently, there is limited knowledge about mass production methodologies and ex-situ infection of H. vastatrix that lead to the development of different health characterization studies of Coffea or disease phenotyping. In this context, the aim of this research was to develop a simple protocol for the mass production of coffee rust uredospores under controlled conditions and to determine their infection in coffee seedlings. Uredospores of H. vastatrix were collected from infected plants in the “Chontal” coffee-growing area in San Martín, Peru. The viability of uredospore germination was evaluated, and a uredospores suspension (2 x 105 uredospores/mL) was prepared to inoculate coffee seedlings. Incidence and sporulation rates were evaluated after 43 days of inoculation. During the multiplication process of H. vastatrix uredospores, using controlled conditions (23±1 °C, ≈ 80% relative humidity and photoperiod of 16 hours of light) under an innovative system, the first symptoms of chlorosis were observed on coffee leaves 20 days after inoculation. Our findings show a 100% incidence of inoculated coffee plants with an average of 54 mg of H. vastatrix uredospores per plant and a 1.38 x 10-1 mg/cm2 sporulation rate. Finally, here we report a protocol that allows mass multiplication of H. vastatrix uredospores under controlled conditions, that would be useful in any time for coffee leaf rust bioassays.
Analysis of inventories through a statistical forecast model in a company Peruvian
Authors: Yanque Vara David , Rodríguez Meza Mari Carmen , Vásquez Campos Salomón Axel
Published: July 2023

The importance of the study falls on the main objective of analyzing inventories through statistical forecasts in a pharmaceutical company. The research approach was quantitative, cross-sectional, non-experimental design and descriptive level. The study population was the information from the inventory of the company for the year 2022, likewise the sample consisted of two products classified in item A. According to what was elaborated in the article, it is concluded that the products selected in group A, they have a 15% participation in the company's inventories, however, they represent 86.6% according to their unit cost and 45.3% of inventory valuation according to their value, also according to their profit contribution they have a 49.76% participation. And, according to the analysis of the forecasting methods, it was determined that the ideal for both products 002 and 005 is the seasonal index method, considering the MAPE (average absolute percentage error) lower, reaching 28.96% and 27.28% respectively. The economic order quantity was determined where it was seen that for product 002 it is 50392 and product 005 is 73217.
Investment Portfolio Management equities applying Markowitz Theory
Authors: Zavaleta Lamela Rainer Víctor
Published: July 2023

Investment Portfolio Management equities is based on the investor reasoning behavior minimizing risks and maximizing profits, benefits offered by Markowitz Portfolios Theory (TPM onwards). The goal is to manage investment Portfolios equities applying TPM to determine from this one if a financial assets Portfolios negotiated in Standard y Poor's 500 (SyP 500) deals with the maximizing investor profits considering a minimal variance. The population was made by 505 enterprises composed by 11 economic sectors SyP 500 rate. Some basic analysis filters were used in order to obtain the same and 34 enterprises our of the main economical sections of SyP 500 rate were identified to which TPM was applied to investment Portfolio Management equities and financial tools such as FINVIZ, Yahoo finance, Select Sector supported by Microsoft Excel were used. The research design was pre-experimental with a quantitative-qualitative approach. One of the conclusions was that the Investment Portfolio Management equities had a 52,379% performance producing a 3,086% and 5,892% monthly expected profits risk.
Validación de un método de aislamiento para Legionella pneumophila por medio de membrana de filtración
Authors: Garzón Marcela Gómez , Lara Sanabria Alejandra , Cufiño Cristian , Ortiz Jimenez Diana , Jimenez Rojas Adriana
Published: July 2023

El aislamiento y detección de Legionella pneumophila en agua potable puede ser un proceso difícil, debido a que algunas de las técnicas existentes no recuperan la cantidad establecida por normas internacionales y al ser un microorganismo exigente, se requiere de medios especiales para su crecimiento. El objetivo del estudio fue validar un método de concentración por medio de la implementación del equipo Celltrazone® para lograr la recuperación en agar BCYE, utilizando muestras de agua potable con diferentes concentraciones de la bacteria. Para lograr este objetivo, se ensayaron tres tipos de tratamiento para el filtro obtenido después de la filtración por el equipo Celltrazone®, el vortex, sonicado y agitación, sin embargo, al no aplicar ningún procedimiento al filtro y realizar su siembra directa se obtuvieron los mejores resultados. El análisis estadístico demostró que con el método seleccionado se puede concentrar hasta 1x102 UFC, se alcanzó una sensibilidad del 100%, una especificidad del 80% y un valor de exactitud del 87,5%. El método de filtración de membrana utilizando el equipo Celltrazone® permitió aumentar la concentración de L. pneumophila en agua potable, cumpliendo con los intervalos normalizados por ISO y la OMS, por lo tanto, el método es apto para su aplicación asegurando resultados confiables.
Hábitos lectores en Educación secundaria: Propuesta booktuber
Authors: De-Cecilia-Rodríguez Cristina , Rodríguez-Gallego Margarita R. , Ordóñez-Sierra Rosario , Domene-Martos Soledad J.
Published: July 2023

El objetivo de esta experiencia ha sido realizar una evaluación inicial, a través de un cuestionario, para detectar las necesidades y hábitos de lectura en estudiantes del tercer curso de la ESO de un centro de la provincia de Sevilla. Los resultados del cuestionario explicitan la falta de hábitos lectores, aunque los estudiantes plantean que cuando leen lo hacen por placer y que si tuvieran más tiempo libre leerían más; lo que nos ha llevado a diseñar, desarrollar y evaluar una práctica lectora denominada booktuber en la asignatura de Lengua Castellana y Literatura para fomentar los hábitos lectores. Los estudiantes han realizado una video-reseña como booktubers para analizar el libro Marianela de Pérez Galdós; permitiendo esta práctica lectora aumentar su motivación, capacidad de exposición y memoria ante la cámara, A través del cuestionario final de satisfacción se ha detectado que esta práctica les resulta más atractiva que el examen escrito que realizan de las lecturas obligatorias.
How Do Social Media Machines Affect Self-Concept Research?
Authors: Fehér Katalin , Katona Attila I.
Published: July 2023

Advanced digital technologies broadly penetrate self-activities, such as algorithms, machine learning, or artificial intelligence. This trend is most evident on social media, where contents, attitudes and evaluative judgments meet on technology-driven platforms. Moreover, human networks also started communicating with social bots or conversational interfaces. All these challenges can trigger a redesign of self-concept via technology. Therefore, the paper investigates how social media machines affect self-concept-related academic research. First, pioneers of the field are presented. Second, the self-concept research in digital technology and social media is summarised. Topic networks illustrate critical research fields with the latest trends and future implications. Last but not least, we also investigate how emerging media phenomena affect academic trends in the case of social bots or fake news. The study aims to support the connected research in psychology, business, management, education, political science, medicine and media studies with an understanding of the latest trends. The additional goal is to highlight the potential of market-based research cooperation with academia supporting significant developments and funding.
COGNITIVE DIMENSION OF WORD-FORMATION SEMANTICS IN INTRANUMERAL WORD FORMATION: EVENT-BASED CONTENT
Authors:   Vasyl Stefanyk Precarpathian National University, KOSTRYBA Оlha
Published: July 2023

The article proposes to consider the cognitive aspect of the word semantics of derivatives with a mutational type of derivation in the intra-numerical word formation. The analysis is implemented by involving a propositional-semantic frame method that promotes cognitive modeling of derivatives of seven word-forming meanings, taking into account the hierarchy of frame structures (frame→ subframe → slot → three-element propositional scheme → three-component specific proposition). The presence of a significant action as one of the three constituents of the deep level of language, namely its core, is justified. The central predicate is inherent in derivatives with a mutational type of derivation, which are based on an event proposition. The thematic filling of word meanings of cognitive content is established, as well as verbalized slots, by which we understand the motivational seme of each lexical-semantic variant of the non-derived vertex numeral. It has been found that word meanings can be grouped based on mental slots or function based on a common theme. Additionally, their verbal manifestations have been identified. The word semantics of derivatives with a mutational type of derivation can be characterized by semantic increments, which are set within each lexical meaning, as well as increments at the level of propositions, namely left and right-sided actors and the predicate component. For the first time in Ukrainian studies, the emphasis has shifted from the description of frame structures represented by word nests to a word value that is established according to the onomasiological principle (taking into account the distinction of the functional-semantic category of quantity from the word semantics). This approach will facilitate a comprehensive description of word semantics, complementing the achievements of derivatology with cognitive discovery. As a result of this work, the actant components of propositions, represented by quantitative content, have been typologized. This enables the establishment of the cognitive aspect of word-formation semantics in derivatives derived from numerals. The prospects of this research also include data computerization, which will facilitate searching for words based on queries such as “frame”, “cognitive slot”, “verbalized slot”, “propositional scheme”, “proposition”, and “word-forming meaning”.
Stent thrombosis: Prevention and management
Authors: P Rajendra Kumar Jain , Chitnis Nishad
Published: July 2023

Stent thrombosis (ST) is a persistent and important clinical problem. Stent thrombosis has been defined and classified by the Academic Research Consortium (ARC). We have reviewed the data available on the incidence of ST in various registries and trials. The incidence of ST is higher with DES compared to BMS. ST incidence is highest with first generation DES but reduces significantly with second and third generation DES. We have reviewed the factors which predict a higher incidence of ST. These can be divided into patient, lesion and procedure characteristics. The upcoming new technologies and their potential impact on ST have been discussed. Finally, the methods of minimising the incidence of ST in practice have been discussed. Keywords: Stent thrombosis; Coronary stent; Drug eluting stents
Management of traumatic enterocutaneous fistula
Authors: T Lakshmikanth , B Ramana Reddy
Published: July 2023

One of the most devastating complications to develop in the general surgical patient is an enterocutaneous fistula (ECF). Critically ill patients suffering trauma, thermal injury, and other acute intra abdominal pathology are at unique risk for this complication as well. This case report is to describe the epidemiology of ECF in the setting of trauma and critical illness, nutrition in injured/critically ill patients with ECF, wound care, surgical management of the ECF. Keywords: Enterocutaneous fistula; Trauma; Management.
Bipolar arthroplasty for unstable Intertrochanteric fractures of femur
Authors: IV Reddy
Published: July 2023

Intertrochanteric (IT) fractures of femur are common in elderly people with osteoporotic bones and often the result of minor domestic falls. Osteoporosis coupled with a tendency to fall is responsible for high incidence of hip fractures at this age. Life expectancy of Indian population is steadily increasing and this inturn, increases the geriatric population and the hip fractures.
Early detection of breast cancer - Finding an ‘Indian solution to an Indian problem
Authors: P Raghu Ram
Published: July 2023

More than one million women worldwide are newly diagnosed with breast cancer annually. Worldwide, a woman dies of breast cancer every minute. In India well over 100, 000 women are newly diagnosed with breast cancer every year; a staggering number that has overtaken cervical cancer to become the leading cause for cancer related death among women in metropolitan cities. The number of newly diagnosed breast cancers in India is expected to increase to 130, 000 per annum by 2020. This is only the tip of the iceberg, as many breast cancers are not reported to the Cancer Registry & many states do not have a robust Cancer Registry.
Quality assurance of modern image guided 3D-conformal radiotherapy treatments
Authors: K Krishnamurthy , A Anandagiri Babu , PBLD Prasad , K Kavi Arasu
Published: July 2023

Purpose: To describe the Quality Assurance (QA) methods of modern Three-dimensional conformal radiotherapy (3DCRT) treatments such as image guided Intensity-modulated radiation therapy (IMRT), RapidArc, Stereotactic radiosurgery (SRS)/ Stereotactic fractionated radiation (SRT) to ensure quality of treatments delivered to cancer patients. Materials and methods: 3D-RFA and Ionisation chambers were used for the machine specific QA. Imatrixx-2D array with locally fabricated phantom and another locally fabricated spherical phantom with ionization chambers is used for relative and absolute QA respectively. Electronic Portal Imaging Devices and Epiqa software is used for the QA with portal dosimetry. Varians Eclipse and Brainlab’s Iplan treatment planning systems were used for treatment plans and dose calculations. For relative dosimetry the planar dose matrices are analysed using global Gamma Index criteria of 3mm distance to agreement (DTA) and 3% dose difference. The QA of Machines and patient treatments were carried out using national and international protocols. Results: The maximum deviations of percentage of dose points in which γ>1 are 1.98 in relative dosimetric QA and 1.5 for absolute QA in the delivery of IMRT, RapidArc and SRS/SRT treatments. The mean deviations and Standard deviation (SD) values are less in portal dosimetry than that of phantom studies in relative dosimetry and all the absolute dose deviations are less than that of relative dose deviations. Conclusion: The results of machine specific QA as well as relative and absolute dosimetric QA of patient treatments are well within the acceptable limits of values mentioned in the national and international protocols. The study ensures the accuracy and quality of the treatments delivered to the patients at our oncology center. Keywords: Quality assurance, RapidArc, Portal dosimetry, Gamma index, Image guided radiotherapy
Screening and prevention of cervical cancers
Authors: GVVS Kanaka Bushanam , B Srinivasa Rao , M Sailaja , G Sakuntala Devi
Published: July 2023

Cervical cancer in India ranks as the 2nd most frequent cancer among women and the 2nd most frequent cancer among women between 15 and 44 years of age. As per National Cancer Registry, crude incidence and mortality rate due to cervical cancer in India is 134 per 1,000 and 74 per 1,000 women respectively. Age adjusted incidence rate of cervical cancer reported for six cities are - Bangalore 18.1, Bhopal 18.7, Chennai 24.8, Delhi 17.6 and Mumbai 13.0 per 100,000 (Indian Council of Medical Research, 2006). Several screening methods, both traditional and newer technologies, are available to screen women for cervical pre cancers and cancers. No screening test is perfect and hence the choice of screening test will depend on the setting where it is to be used. In this article, the recommendations for screening and prevention of cervical cancer are discussed. Keywords: Cervical cancer; Screening; Prevention; Recommendations
Adalimumab treatment in adult patients with refractory non-infectious uveitis
Authors: ESEN Ebru , IŞIK Püren , SIZMAZ Selçuk , DEMİRCAN Nihal
Published: July 2023

Purpose: To assess the efficacy of adalimumab treatment in patients with refractory non-infectious uveitis.

Materials and Methods: A retrospective analysis was carried out on patients with chronic non-infectious uveitis treated with adalimumab for longer than 12 months. All patients had active intraocular inflammation and were nonresponsive to other immunosuppressive agents before initiating adalimumab treatment.

Results: Twenty-one patients (39 eyes) were treated with adalimumab for a mean duration of 26.2 ± 13.2 months. Eleven patients (52.4%) remained relapse-free during the treatment. In only one patient (4.8%) adalimumab was switched to another drug due to insufficient response. Adalimumab treatment was discontinued in five patients (23.8%) after an attack-free period of at least 18 months.

Conclusion: Adalimumab is an effective and well-tolerated therapeutic option for patients with refractory non-infectious uveitis, to achieve and maintain disease quiescence.
COVID-19 and persistent inflammation, immunosuppression and catabolism syndrome
Authors: TATLISULUOĞLU Derya , TURAN Güldem
Published: July 2023

Purpose: Multiple organ failure (MOF) is a disease group that necessitates intensive care monitoring and carries a significant mortality rate. If these individuals are not dead as a result of early MOF, they will either quickly restore immunological balance or their immunological dysfunction may persist, resulting in chronic critical illness (CCI). Some of these patients have CCI, which is characterized by chronic inflammation, immunosuppression, and the syndrome of catabolism (PICS). With this study, we aimed to evaluate PICS cases in our intensive care unit, their effects on mortality, and their biomarkers.

Materials and Methods: This is a retrospective, observational study involving 190 patients diagnosed with acute respiratory distress syndrome (ARDS) due to SARS-CoV-2 and followed up in the ICU. Patients' laboratory data and body mass index (BMI) were compared between the first and twenty-first days of ICU admission. In addition, the patients were evaluated according to PICS utilizing the number of days they spent in the ICU, CRP, albumin, prealbumin, lymphocytes, and BMI data.

Results: The laboratory values of the patients on the 21st day were as follows, and the results obtained were statistically significant when compared with the values on the 1st day. Albumin 2.56±0.57 g/L, prealbumin 9±15 g/L, d-dimer 4.41±4.70 (interquartile range (IQR): 2.53-4.76) µgFEU/mL, fibrinogen 497±189,35 mg/dl, hemoglobin 10.15±1.82 g/dL, leukocytes 13.94±8.12 (IQR: 12.34-7.69) 109/L, immature granulocyte 1.16±2.13 (IQR: 0.46-1)109/L and BMI of 26.92±3.27 (IQR: 26.7-4.8). Again in these patients, lymphocyte values were 0.92±0.80 (IQR: 0.71-0.74)109/L, CRP was 101.42±99,96 mg/L, and platelet values were 214.24±128.08 109/L.

Conclusion: PICS is a significant condition affecting mortality and morbidity in critical care patients. In this group of patients, immature granulocytes may also serve as a useful biomarker. Due to the lack of studies regarding PICS, we are in the premature phase of understanding the pathogenesis and management of PICS and therefore need more comprehensive research regarding the topic.
Effects of herbal mixture on burned rat skin infected with Pseudomonas aeruginosa
Authors: YİĞİT Serdar , GEZER Arzu , BALKAN BOZLAK Çiğdem Eda , ÇELİK Seda , BİNGÖL Seyit Ali
Published: July 2023

Purpose: The purpose of this study is to investigate the healing impact of an ointment derived from the Alkanna tinctoria plant upon Pseudomonas aeruginosa-induced infections.

Material and Methods: In this study, 18 male adolescent rats (mean age 6 weeks) weighed an average of 180 g were used. Animals were divided into 3 groups. Group 1: Control group (consisting of burns, no treatment was done), Group 2 (P. aeruginosa): Burn was created and infected with P. aeruginosa, Group 3 (Cream): P. aeruginosa was used to infect the burns area and the herbal mixture was administered twice a day, once in the morning and once in the afternoon. Under anesthesia, the backs of the rats were shaved, and a specially produced steel bar with a diameter of 1*1 cm was immersed in boiling water for 15 seconds before being applied to their backs for 20 seconds. The burned area was subsequently infected with the ATCC Pseudomonas aeruginosa strain, and samples were collected 24 hours later. To detect bacterial growth in this area, the samples were inoculated on blood and EMB (Eosin Methylene Blue) media in a microbiology laboratory. After inoculation, the animals were placed in separate sterile cages and randomly divided into three groups. Once the growth was observed, the tissue and blood samples were harvested from the rats on the 2nd, 7th, 14th, and 21st days.

Results: Epithelial regeneration in this group was more prominent. Vascularization was remarkable on the 2nd day, especially in the group in where we induced a burn and applied the ointment. VEGF levels increased more in the ointment group than in that of others. On the 2nd day of the study, the average bacterial count was 105 in sample of both 2nd and 3rd groups. At the end of the study, while the average of bacterial count was increased in the 2nd group, the average of bacterial count was decreased in the 3rd group.

Conclusion: It was concluded that the ointment obtained from A. tinctorial successfully repaired the epithelial tissue and contributed to the healing of wounds by modifying increasing VEGF in the blood. However, further research is needed before this ointment can be highly recommended for therapeutic usage
Factors affecting the false negativity of fine-needle aspiration biopsy in thyroid nodules with indeterminate cytology
Authors: ÖZEMİR İbrahim Ali
Published: July 2023

Purpose: False negative results of fine needle aspiration biopsies (FNAB) remain one of the most important problems in the management of thyroid nodules. The aim of this study was to evaluate the factors affecting the false negative results of FNAB, especially in thyroid nodules with indeterminate cytology.

Materials and Methods: Patients with thyroid nodules who underwent FNAB and subsequent thyroidectomy between January 2017 and January 2020 were included in the study. FNAB was performed on suspicious nodules according to the TIRADS classification. Nodules with "atypia/follicular lesion of undetermined significance (AUS/FLUS)", "non-diagnostic (ND)" cytology or "follicular neoplasm/suspicious for follicular neoplasm (FN/SFN)" according to FNAB were defined as "indeterminate cytology (IC)". Nodules were analyzed in two groups. Nodules with false negative FNAB were included in Group-1, while nodules with true positive and true negative FNAB were included in Group-2. Demographic and clinical data, pathologic results and genetic profiles of the patients were statistically compared for all patients and IC group separately.

Results: The results of FNAB and final pathology were discordant in 94 patients (Group-1) and concordant in 233 patients (Group-2). In the IC subgroup, 56 of 95 patients were in IC/Group-1 and 39 patients were in IC/Group-2. The accuracy of FNAB was statistically significantly higher in the presence of extrathyroidal extension (71.4% vs. 30.8%), perineural/lymphovascular invasion (60.0% vs. 29.6%), classical variants (68.5% vs. 50.7%), non-encapsulated tumors (67.9% vs. 50.0%) and multicentricity (47.2% vs. 24.1%). In the IC group, the presence of thyroiditis (75.0% vs. 49.2%) and high serum Anti-TPO levels (60.0% vs. 30.7%) increased the rate of false negativity on FNAB. High serum Neutrophil to Lymphocyte Ratio (NLR) and small tumor size also increase the false negativity of FNAB, especially in IC group patients.

Conclusion: The diagnostic accuracy of FNAB is increased in classical variant tumors and in tumors expected to be aggressive due to presence of extra-thyroidal extension, perineural/lymphovascular invasion, non-encapsulated tumors and multicentricity. It should be kept in mind that the false negative results of FNAB increase in the presence of thyroiditis, high level of serum anti-TPO and high level of NLR.
Evaluation of demographic, clinical characteristics and cost of immigrant patients with end-stage renal failure
Authors: TELAFARLI Mehmet Ali , ÇAKIR Adem
Published: July 2023

Purpose: Due to wars and disasters, people migrate forcibly due to their need for safe housing and health care. In our study, we aimed to the demographic and clinical typical of immigrants with end-stage renal disease and to make a cost analysis.

Materials and Methods: Our study is single-center and retrospective. Migrant patients who have end-stage renal disease who met the study criteria were included in the study. Demographic data, clinical data, laboratory data and treatment cost data of the cases were added to the previously created form.

Results: Our study was conducted with 696 patients. 64.2% of the cases were female and the median age was 67 years. 65.5% of the cases were of Syrian nationality. Hemodialysis was applied to all of the cases, of which 47% were urgently. 55.2% of these cases were hospitalized and mortality was observed in 13.2% of all cases. Age was statistically higher in cases with mortality. Urea and creatinine in patients with mortality were significantly higher; pH, HCO3 and GFR were statistically lower. Mortality was statistically higher in cases requiring urgent hemodialysis and hospitalized in the ICU. The cost of health was statistically higher in surviving cases. Again, in patients who were hospitalized, both the time allocated for care and the cost of health were statistically higher than in outpatients.

Conclusion: Establishing routine dialysis programs by identifying immigrant cases with end-stage renal disease will both reduce mortality and morbidity for patients, reduce health costs in countries, and reduce emergency department densities.
Effect of serum adropin levels on circulating endothelial dysfunction biomarkers in COVID-19 patients
Authors: GÜNEŞAÇAR Ramazan , DEMİR EKŞİ Durkadın , ALPAY Ali Seydi , HANİKOĞLU Ferhat , ERDOĞAN Haluk
Published: July 2023

Purpose: Several studies show that the symptoms of severe COVID-19 infection reflect the clinical phenotype of endothelial dysfunction and share common pathophysiological mechanisms with endothelial dysfunction. Therefore, the aim of the study was to investigate the effect of serum adropin levels on endothelial dysfunction biomarkers and determine whether adropin could be a new biomarker for COVID-19.

Materials and Methods: The study included 40 patients with mild/moderate COVID-19, 48 patients with severe/critical COVID-19, and 37 controls. Serum adropin and circulating biomarkers of endothelial dysfunction including asymmetric dimethylarginine (ADMA), endothelin-1 (ET-1), endothelial nitric oxide synthase (eNOS), soluble intercellular adhesion molecule-1 (sICAM-1) and plasminogen activator inhibitor-1 (PAI-1) levels were determined by micro-ELISA.

Results: Serum adropin levels were found to be significantly higher in COVID-19 patients (165.2±11.49 pg/ml) than in controls (85.46±12.08 pg/ml). Serum adropin levels of patients with severe/critical symptoms (194±16.23 pg/ml) were significantly higher than the patients with mild/moderate symptoms (130.6 ±14.53). In addition, serum ADMA, eNOS, and, ET-1 levels were significantly higher in the COVID-19 subjects (150.5±8.67 ng/ml, 172.4±14.01 pg/ml, 159.3±10.19 pg/ml, respectively) than that those in the controls (104.5±9.182 ng/ml, 141.4±17.74 pg/ml, 100.1±11.37 pg/ml, respectively). Significant positive correlations were found between adropin and ADMA, eNOS, ET-1, sICAM-1, and PAI-1 levels in the patients.

Conclusion: We suggest that adropin may be a new potential biomarker for COVID-19 and an important molecule in restoring endothelial cell damage. Positive correlations between serum adropin levels and ADMA, eNOS, ET-1, sICAM-1 and PAI-1 levels in patients suggest that adropin may compensate for damage to endothelial cells.
Implementación de BITCOIN en El Salvador
Authors: Garay Rodríguez Andrya Miriam
Published: July 2023

Septiembre  7 de 2021 en El Salvador adopto el  BITCOIN está criptomoneda como moneda de curso legal con el fin de facilitar la inclusión financiera e impulsar el crecimiento económico, por lo que el presente articulo busca analizar el uso BITCOIN en las micro y pequeñas empresas en el desarrollo de sus transacciones comerciales ante el establecimiento de esta moneda. Para ello se realiza un estudio cualitativo mediante encuestas a 133 empresas definidas en un muestreo no probabilístico por conveniencia, a fin de obtener información acerca del uso del BITCOIN en su implementación como moneda de curso legal que permitiera identificar su posicionamiento de las empresas con esta estrategia. En las empresas encuestadas, se determina el bajo nivel de aceptación en el uso del BITCOIN, para cobrar o pagar en la realización de sus operaciones comerciales y aquellos empresarios que la aceptaban lo retenían en la billetera de Chivo emitida en el Gobierno en Dólares. La mayoría de los negocios manifiestan que no han percibido un beneficio como efecto en la implementación del BITCOIN. El BITCOIN como moneda de curso legal se estableció en El Salvador como una medida de inclusión financiera, donde 40,00% de las personas tienen acceso a una cuenta bancaria, pero el desconocimiento de funcionamiento de las criptomonedas ha llevado a que no la acepten en su uso, lo que presenta un reto de formación. La inclusión financiera no debe hacerse desvinculada de mecanismos de alfabetización financiera para que cumpla sus objetivos de uso, acceso, calidad y bienestar, donde el mostrar a las poblaciones vulnerables los beneficios y riesgos de los distintos productos entre ellos las Criptomonedas se vuelven relevantes para su implementación.
Comprometidos con la renovación de la acreditación del programa de Contaduría Pública de la Universidad Libre, seccional Barranquilla
Authors: Jiménez Castro Joaquin
Published: July 2023

En agosto de este año se recibirá la visita de los pares académicos del Consejo Nacional de Acreditación, CNA, con miras a la renovación de la acreditación del programa de Contaduría Pública. Simultáneamente, el programa de Administración de Negocios Internacionales se viene preparando para someterse a la acreditación de alta calidad. Este reto lo asumió un equipo de docentes, administrativos y directivos de la Facultad CEAC, comprometidos con altos niveles de exigencia para garantizar la calidad del programa, cuya fortaleza está en la formación de sus líderes, quienes guían los esfuerzos de la comunidad académica hacia las metas de los objetivos de desarrollo sostenible, respetando la identidad cultural de la región y el país.

Acorde a la visión de nuestra Alma Mater, el programa de Contaduría Pública busca fortalecer la solución pacifista del entorno en el que se encuentran inmersos los estudiantes y egresados, promoviendo su liderazgo y el mejoramiento continuo de los procesos contables, económicos y administrativos. Este programa cuenta con el marco legal de la International Federation of Accountants (IFAC) y del Institute Management Accountant, en el ámbito internacional, y con el marco Legal Nacional de la Junta Central de Contadores, el Consejo Técnico de la Contaduría y la Contaduría General de la Nación.

La Universidad pretende que sus Contadores Públicos estén capacitados para manejar las normas internacionales de información financiera y el aseguramiento de la información financiera (NIIF y NIIA, en su orden). Es decir, que no sólo se busca el desarrollo de las competencias cuantitativas de la formación contable, sino que se fortalece su interpretación. Se busca desarrollar las habilidades humanas del profesional contable ante el inminente reto que representa la inteligencia artificial.
СОПОСТАВИТЕЛЬНО-ТИПОЛОГИЧЕСКИЕ ИССЛЕДОВАНИЯ В ТРУДАХ ПРОФЕССОРА И. Д. БУХАЕВОЙ
Authors:   Бурятский государственный университет имени Доржи Банзарова, Д. Ш. Харанутова
Published: July 2023

В статье предпринята попытка открыть одну из граней удиви-тельного человека, большого ученого И. Д. Бухаевой, научные приоритеты которой связаны с фонологией. Работа посвящена ее фонологическим исследованиям, написанным в сопоставительно-типологическом аспекте. Раскрываются основные фонологические идеи профессора по проблемам фонетической бурятско-русской интерференции сегментного уровня. Особое внимание уделено сопоставительным исследованиям по звуковой системе бурятского и русского языков с позиций когнитивной лингвистики. Подчеркивается, что впервые исследуется синтагматическая фонология бурятского языка в аспекте порождения речи, ибо специфика фонетико-фонологической системы заключена в синтагматических отношениях составляющих ее единиц. По мнению И. Д. Бухаевой, сегментация речевого потока в бурятском языке представляет собой специфический способ реализации семантической информации, отличный в этом плане от русского языка.
КОМБИНАТОРИКА БУРЯТСКИХ ГЛАГОЛОВ ЭМОЦИИ И СИНТАКСИЧЕСКОЕ ВЫРАЖЕНИЕ СТИМУЛА
Authors:   Институт монголоведения, буддологии и тибетологии Сибирского отделения Российской академии наук (ИМБТ СО РАН), Н. Б. Даржаева
Published: July 2023

В статье впервые представляются результаты специального изучения комбинаторики бурятских глаголов эмоции и синтаксического выражения валентности стимула эмоциональной реакции. Целью исследования является выявление моделей управления у глаголов эмоции на уровне сложного предложения и их сочетаемости с развернутыми формами Стимула-события. Для достижения этой цели решались следующие задачи: на основе корпусных данных пронаблюдать комбинаторику основных семантических типов эмотивных глаголов, установить типы бипредикативных конструкций, главным предикатом в которых выступают эти глаголы, а так-же зависимость их комбинаторики от семантических свойств. Автор придерживается концепции, согласно которой стимулом эмоции выступает Событие, а не Каузатор. В ходе исследования применяются методы корпусного анализа, лингвистическое наблюдение, описание, методы контекстного и компонентного анализа. В результате исследования разграничены два типа Стимулов: событийного и информационного характера. Для групп глаголов положительной и отрицательной эмоции, а также страха описан предпочтительный круг бипредикативных конструкций, выполняющих роль Стимула-события. Предпочтительная комбинаторика обусловливается семантическими характеристиками как глагола эмоции, так и самих конструкций. Статистическая картина сочетаемости глаголов эмоции отражена в табличной форме. Предпринятое исследование послужит толчком как для дальнейшего изучения комбинаторных свойств у более широкого круга эмотивных глаголов, так и для включения в анализ свернутых форм Стимула-имени.
СЕМАНТИКА ЦВЕТОЛЕКСЕМЫ КАРА ‘ЧЕРНЫЙ' В ТУВИНСКОМ ЯЗЫКЕ
Authors:   Институт монголоведения, буддологии и тибетологии СО РАН, Ч. С. Цыбенова
Published: July 2023

В статье на основе данных лексикографических источников и материалов ассоциативного эксперимента рассматривается цветолексема кара ‘черный’ в со-временном тувинском языке. Основной целью статьи является анализ лексических значений данной цветолексемы в сопоставлении с его значениями, представленными в ассоциативном словаре-тезаурусе носителей тувинского языка. Проведенное исследование показывает, что семантика кара, эксплицированная в различных текстовых материалах и языковых употреблениях, многозначна. Всего по лексикографическим источникам определено четыре лексико-семантических варианта кара. Выявлено, что лексико-семантические варианты цветолексемы с психологически реальными значениями, представленными в ассоциативном тезаурусе тувинцев, совпадают не всегда. Некоторые ассоциативные значения, дополняя семантику указанной цветолексемы, тесно связаны с архетипическими образами, другие обусловлены спецификой тувинского языка. Материал показывает, что семантика данной цветолексемы разнообразна, отражает не только предметный, материальный мир, но и внутренний, передает эмоции и чувства.
АДМИНИСТРАТИВНАЯ ТЕРМИНОЛОГИЯ В ЗАБАЙКАЛЬСКОМ ДОКУМЕНТНОМ ДИСКУРСЕ XVII в.
Authors:   Институт русского языка им. В. В. Виноградова РАН, А. П. Майоров
Published: July 2023

Статья посвящена рассмотрению административных терминов князец, лутчие люди как инструментария документного дискурса XVII в., выполняющего функцию дискурса власти. Дискурсивный анализ терминологической лексики сферы государственного управления предполагает в первую очередь характеристику специфики государственного устройства Московской Руси данного периода. В этом случае методологически оправданным представляется применение положений кратологической теории М. Фуко. В рамках понятийного аппарата ученого власть русского царя XV‒XVII вв. интерпретируется как власть-господство, а ее олицетворением в период интенсивного освоения территорий Восточной Сибири и Дальнего Востока выступает эпистема колонизации. Рассмотренные автором дискурсивные практики, которые получили отражение в корпусе текстов забайкальской деловой письменности XVII в., свидетельствуют о своеобразном восприятии покорителями Сибири сложной социальной иерархии бурятского общества того времени. Освоение территорий, населенных коренными народами Циркумбайкальского региона, должно было неизбежно сопровождаться межэтническими и межъязыковыми контактами, результатом которых ожидалось бы употребление в русском документном дискурсе автохтонных заим-ствований, обозначающих административные должности в бурятском обществе того времени. Этого не происходит, и отсутствие должностных терминов даруга, зайсан, засул, тайша, шуленга объясняется тем, что все данные терминологические номинации заменяют русские термины князец, лутчие люди. В контексте упомянутой эпистемы колонизации и выстраивания жесткой вертикали власти-господства разграничение инородцев по социальному статусу оказывалось не нужным. Замещение автохтонных заимствований русскими терминами князец (с вариантами княжец, князек), лутчие люди связано с выполнением данными терминами функции дискурсем по упрочению имперского сознания у бывших и новых российских подданных, а также закреплением за термином представления о вассальной зависимости ясачных людей. Автор статьи счел необходимым отдельно охарактеризовать свое употребление слова термин в связи с неоднозначным толкованием историками языка его применения в диахронном аспекте.
Effect of matrix rhythm therapy on pain, disability, and quality of life among patient with frozen shoulder
Authors: Chamola Sunil Kumar , Kanuja  , Chamola Yogesh , Mohapatra S C
Published: July 2023

Frozen shoulder also known as adhesive capsulitis is a condition that causes pain and stiffness in the shoulder joint. It occurs when the tissues in the shoulder joint become thick and stiff and making it difficult to move the shoulder.

It is an experimental design conducted in SGT medical college amongst 40 to 60 years population in the department of physiotherapy collaborative to the department of community medicine.

To investigate the impact of Matrix Rhythm Therapy on shoulder joint discomfort, restricted ROM, and quality of life.

There were three scale used NPRS, SPADI and WHOQL. It was observed that in comparison of conventional group the experimental group was more significant with highly effective results.

Shoulder pain was common in today’s perspective due to cause of change in lifestyle and quality of life.
Increased preanalytical errors during Covid-19 Pandemic
Authors: Tyagi Surbhi
Published: July 2023

The clinical laboratories worldwide have faced numerous obstacles due to the COVID-19 pandemic. In the midst of this outbreak, mistakes that occur during the preanalytical phase of sample collection, transportation, and processing can result in unfavorable clinical outcomes. Therefore, the aim of this investigation was to ascertain and contrast the rate at which blood specimens are rejected by a clinical laboratory and to analyze and compare the types of preanalytical errors during the pre-pandemic and pandemic periods.

The present retrospective study was done in Chhatrapati Shivaji Subharti Hospital; India. Information was gathered from two distinct time periods - the pre-pandemic phase, which spanned from December 30th, 2019 to March 22, 2020, and the pandemic phase, which ran from March 23th to November 30, 2020. The rate of rejection for blood samples was established by determining the percentage of blood collection tubes containing preanalytical mistakes out of the total number of tubes received.

A total of 102,000 blood samples were examined, out of which 40,800 (40%) were collected during the pandemic. The pandemic phase witnessed a significantly higher rate of rejection of blood samples (4%) as compared to the pre-pandemic phase (1%) (P < 0.001). In both phases, the most common preanalytical error was the clotting of samples. There was a significant increase in improperly labeled samples during the pandemic, while there was a notable decrease in hemolyzed samples.

Given the prevailing situation of the Corona pandemic, altered logistics have led to a significant surge in preanalytical errors and consequent rejection of blood specimens in clinical laboratories. Therefore, it is imperative to take corrective measures at different levels to minimize preanalytical errors, which would ultimately enhance patient care and optimize the utilization of resources.
The dependence of the biodegradable ZX10 alloy corrosion process on the structural factors and local pH level
Authors:   Togliatti State University, Myagkikh P. N. , Merson E. D. ,   Togliatti State University, Poluyanov V. A. ,   Togliatti State University, Merson D. L. ,   Togliatti State University
Published: July 2023

Magnesium biodegradable alloys are a promising material for self-dissolving surgical implants. Magnesium is known to be sensitive to electrochemical corrosion due to the galvanic effect between the matrix and particles of secondary phases and inclusions. Another important factor is the pH level. The behavior of certain chemical reactions depends on the pH level, so one can assume that the pH level of a corrosive medium at the material surface is a factor determining what chemical reactions can occur there. Finally, there is evidence that variability of the crystallographic orientation of the grains may be a cause of anisotropy of corrosion properties. The purpose of this work is to reveal the influence of the electrode potential of the microstructural elements, the crystallographic orientation of the grains, and the pH level of the near-surface volume of the corrosion solution on the corrosion process. In the study, sections of 2×1.5 mm were marked on the ZX10 alloy samples, for which maps of the distribution of crystallographic orientations and chemical composition were drawn. To assess the influence of the electrode potential of the particles, the authors carried out a Kelvin probe mapping in the 90×90 µm area. Next, corrosion tests were carried out with video filming of the surface on the marked area. To determine the pH level influence, the solution circulation in the cell was varied. Upon completion of the tests, corrosion products and corrosion damage were examined in detail. According to the results, the pH level in the liquid near-surface micro-volumes has a greater influence than the electrode potential of the particles as it provokes the formation of corrosion products of a different composition, which leads to passivation of the surface areas around the particles. The authors identified two different types of filiform corrosion. For filiform corrosion, a correlation between the corrosion direction and the crystallographic orientation of the grains was established.
Religious and socio-cultural processes in the integration of modern societies (analytical review of the socio-cultural interaction of religious and non-religious Russians)
Authors:   Institute of Demographic Research, a separate subdivision of the Federal State Budgetary Institution of Science of the Federal Research Sociological Center of the Russian Academy of Sciences (IDI FNSC RAS), Kublitskaya Elena A. ,   Institute of Demographic Research, a separate subdivision of the Federal State Budgetary Institution of Science of the Federal Research Sociological Center of the Russian Academy of Sciences (IDI FNSC RAS), Pismanik Matvei G. ,   Perm State Institute of Culture (PGIK)
Published: July 2023

The editorial article presents some problems of mutual understanding be- tween religious and non-religious Russians in a complicated socio-cultural situation. The value foundations of mutual understanding and dialogue between representatives of different worldview positions are considered as the foundation of social consolida- tion in modern society; the interrelation of morality and religion as its "protective" institute is characterized; the principles of dialogue between believers and non-believ- ers are outlined, the most important of which is the scientifically and pedagogically equipped mutual understanding of believers and non-believers on decisive cultural, political and ethical categories and values; substantiated the most important stages of its development.
Проблемы религиозной идентичности кырызов: феномено- лого-социологический анализ прозелитизма
Authors:   UNESCO Department for the Study of World Cultures and Religions, Faculty of International Relations, First President of the Russian Federation, Khan Nadezhda R. , Atambaev Bektur ,   Boris Yeltsin Kyrgyz-Russian Slavic University
Published: July 2023

The article is devoted to the analysis of the religious identity of the Kyrgyz and the perception of Kyrgyz proselytes by the population of the Kyrgyz Republic on the example of the Kyrgyz who adopted the Christian faith in the context of an inter- religious conflict. In the understanding of the population, religious and ethnic identities are the same, which leads to a significant problem in inter-religious relations within the country. The escalation of conflicts arises on the basis of misunderstanding, stere- otypes, prejudice and labels, poor awareness of the population and government offi- cials in matters of religion, as well as the lack of humanity and religious tolerance among some representatives of the Islamic clergy. The attitude of Muslim Kyrgyz to- wards Kyrgyz proselytes is negative, the consequences of which are reflected in the lives of converted Kyrgyz. The growing trend of newly converted Kyrgyz Christians worries both “practicing” Muslims and Muslims who do not follow religious precepts and consider themselves Muslims by ethnicity. The presumption of the Islamization of the Kyrgyz people prevails in the worldview of the Muslim population and becomes the starting point in defending their positions regarding Islam in the life of the Kyrgyz. The study was conducted on the basis of a sociological research, taking into account the phenomenological approach. Not only believers of Islam were covered, but also the Kyrgyz who embraced the Christian faith at a conscious, i.e. at the adult age.