bluuebunny/crossref_metadata_2025 huggingface dataset:
A Study on Knowledge of Health Workers on Vaccine Storage, Distribution, and Cold Chain Management in Yemen
Authors: Sule Victor
Published: March 2023

The success of the Expanded Programme on Immunization (EPI) over the years is attributed to the immunization supply chain, effective logistics systems, and the health professionals who run them. Gaps in knowledge and practices still exist in developing countries and countries with conflict. Due to the paucity of information regarding the subject in humanitarian settings, this study was carried out. This descriptive cross-sectional study was carried out among health workers at the four levels of the healthcare system in 6 governorates in Yemen. A total of 536 health workers provided responses to the online questionnaire between February and May 2022. The study showed that 515(96.1%) and 521(97.2%) of the respondents, respectively, knew the recommended temperature range for storage of Rota and pentavalent vaccines at the health facility. Most respondents, 415(77.4%) and 413(77.0%) knew the recommended storage temperature for measles and BCG, respectively, and 466(86.9%) knew they could be stored at a negative temperature when the need arises. Over two-thirds of respondents only receive vaccines 411(76.7%), and 124(23.1%) receive and distribute vaccines. Vaccine distribution included the use of refrigerated vehicles (15.2%), cold boxes (32.8%), and vaccine carriers (41.6%), both with conditioned ice packs. Despite the protracted and complex humanitarian situation in Yemen, Health workers demonstrated good knowledge and practices of vaccine storage, distribution, and cold chain management, which contributed to the sustenance of immunization services. There is a need for required investment in a cost-effective and sustainable last-mile vaccine distribution approach to ensure equitable availability of vaccines at health facilities and prevent any missed opportunity. Keywords: Cold chain, Distribution, Vaccine storage, Knowledge.
Pictorial Representation on Non-Steroidal Anti-Inflammatory Drugs Product Package and its Influence on Self Medication among Adults in Alimosho LGA, Lagos State, Nigeria
Authors: Afam Dunoi Onwuemezie
Published: March 2023

The purpose of this study is to determine the influence of pictorial representation on product packs of NSAIDs on their self-medication among adults in Alimosho Local Government Area (LGA) of Lagos State. The study is a descriptive inferential cross-sectional study that involved the collection of data from adults and secondary data from a regulatory authority. The data collected from questionnaires administered to adults who were randomly selected across the LGA was analyzed to evaluate the association between pictorial representation on product packs and the practice of self-medication. A time series analysis was conducted with secondary data obtained from the National Agency for Food and Drug Administration and Control (NAFDAC), Nigeria’s medicine regulatory agency, to determine the possible changes or trends that may have occurred with the availability of NSAIDs with pictorial representation. The respondents who participated in the research were adults who were 18 years and above. Of the 652 respondents, 50.8% were males, and 49.2% were females. Demographic profiles, Information sources, and pictorial influence on product packs of NSAID were tested for association with self-medication. Among respondents, 80.6% admitted that they are self-medicated, and 50.6% of them responded that pictorial representation influenced their decision to purchase NSAIDs. A binary logistic regression was performed to ascertain the association between demographic profile and the influence of pictorial representation on product packs of NSAIDs. The overall model was statistically significant, χ2 (9) = 33.097, p< 0.005. The model explained 1.05% (Nagelkerke R2) of the variance in a pictorial representation and correctly classified 62.3% of cases. Keywords: Alimosho, Attitude, Knowledge, NSAID, Perception, Self-medication.
Application of Stem Cells in Pediatric Dentistry
Authors: Maganur Prabhadevi C
Published: March 2023

A stem cell is a master of all cells in the body, which can divide and regrow with regeneration and vascularization. The deciduous teeth, which are not infected and vital with pulp stem cells, help in the formation of adult stem cells. The extracted stem cells from human exfoliated deciduous teeth (SHED) and immature dental pulp stem cells can be harvested as stem cells that form dental tissue regeneration SHED, osteogenic potential 40%, and neurogenic potential either by in vivo or in vitro method. The article here focuses mainly on the stem cell classification of dental stem cells, their characterization, therapeutic application, application in the deciduous tooth procedure, banking of SHED, and recent innovative methods for banking SHED. This review was done to highlight the integral role of pedodontists in educating patients about stem cell banking services and must become a part of such services. Keywords: Human exfoliated deciduous teeth, Immature dental pulp stem cells, Pedodontist, Pediatric dentistry, Stem cells.
Que fatores socioeconômicos influenciam a dinâmica da Ecologia Humana nos saberes etnobotânicos de comunidades circunscritas no Semiárido Mineiro?
Authors: Alves Silva Wesley , Alberto Batista dos Santos Carlos , Martins de Andrade Wbaneide
Published: March 2023

O estudo apresenta uma revisão bibliográfica sistemática dos fatores socioeconômicos que influenciam a dinâmica da Ecologia Humana nos saberes do conhecimento tradicional e dos usos de recursos vegetais por comunidades locais ocorrentes no Semiárido Mineiro. Como metodologia, utilizou-se a Revisão Bibliográfica Sistemática realizada no período de outubro/2021 a janeiro/2022, e norteada pela seguinte pergunta: “Quais fatores socioeconômicos influenciam o conhecimento e os usos dos recursos vegetais utilizados pelas comunidades locais no Norte de Minas Gerais? Para isso, utilizou-se os bancos de dados do Scielo, Scopus, Science Direct, Google Acadêmico e a Biblioteca Digital Brasileira de Teses e Dissertações (BDTD). Foram analisados um total de dezessete trabalhos científicos, realizados em onze cidades do Sertão mineiro. Foi constatado que a utilização dos recursos vegetais é realizada predominantemente pelas mulheres (58,82%), fato pode estar relacionado ao papel delas no cuidar de suas famílias, casas e quintais. Quanto aos aspectos socioeconômicos os dados apontaram que: 1) as pessoas com maior idade detêm mais saberes etnobotânico quando comparada as pessoas mais jovens; 2) os indivíduos com menor renda tendem a apresentar maior conhecimento sobre os vegetais; 3) os entrevistados com menor escolaridade tem mais conhecimentos e manejam melhor os recursos vegetais. Entretanto dados apontam existir várias lacunas desses conhecimentos nas localidades do Norte de Minas Gerais, por isso recomenda-se avançar em estudos mais aprofundados por parte de instituições de ensino e pesquisa com relação a influência desses fatores socioeconômicos sobre os usos, manejo e conservação dos recursos vegetais e das expressões de culturas locais.
Validity of Land Rights Transfer Based on Debt with Collateral of Land Certificate under Indonesian Law
Authors: Setoaji Bima , . Sulistyandari , Kunarti Siti
Published: March 2023

Debt agreement with land certificate guarantee, the accesoir agreement is a guarantee agreement by way of installation of Mortgage which then for repayment if there is negligence / default, an auction is carried out as regulated in Law Number 4 of 1996 concerning Mortgage but in this case it is actually used as a sale and purchase between debtors and creditors. This may cancel the registration of the transfer of land rights that has been carried out by the Purchaser who was previously the Creditor Party. This study uses a normative juridical research method and uses a statutory approach, a conceptual approach, and a case approach. The data sources used are secondary data sources with primary legal sources, secondary legal sources, and tertiary legal sources. Data analysis in this study is a qualitative analysis method with deductive reasoning logic.The results obtained are that the Deed of Sale and Purchase of land rights based on debts and receivables is considered invalid because it is a form of simulation agreement, which is a continuation of accounts payable which if the collateral is a plot of land then it should be the installation of Mortgage Rights. This is based on Article 1131 of the Indonesian Civil Code and the rules contained in Law Number 4 of 1996 concerning Mortgage Rights. Another thing that happened was that the making of the Sale and Purchase Deed was based on the Sale and Purchase Agreement Deed and the Power of Attorney to Sell which contained legal defects so that it affected its validity. The cancellation of land rights can be carried out by means of an application through the Head of the Regency/City Land Office which is then forwarded to the Head of the Provincial Regional Office as described in Article 125-130 of the Regulation of the State Minister of Agrarian Affairs/Head of the National Land Agency Number 9 of 1999 concerning Procedures for Granting and Cancellation of State Land Rights and Management Rights which are the Implementing Regulations of Government Regulations Number 24 of 1997 concerning Land Registration.
Peculiarities of Аpplication of the Institution of Exemption from Liability to Administrative Offenses in the Field of Road Safety, Recorded Automatically
Authors: Georgiievskyi Iurii , Spasenko Viktoriia , Bielikova Maryna
Published: March 2023

The article analyzes the current state of administrative and legal regulation of the institute of exemption from liability for minor administrative offenses. The author notes that there are a number of problematic aspects of application of the Code of Ukraine on Administrative Offenses (hereinafter – CUAO) in the area under study, which is explained by the uncertainty of the legal nature of minority of an administrative offense. The lack of legislative definition of the term "minority offense", the criteria for distinguishing such an act from others, and the lack of regulation of misdemeanors which fall under the signs of minority cause problems of a law enforcement nature. The purpose of the article is to determine the shortcomings of the legal regulation of the procedure for exempting a person from responsibility for committing an administrative offense recorded in the automatic mode, due to the insignificance of the offense and formulating proposals for improving the current legislation in this area. In order to achieve the specified goal, the authors  analyzes the legislation which regulates the procedure for dismissal of offenders referred to in Art. 14-2 of the CUAO in the field of road traffic safety. As a result, it has been established that despite the additional enshrinement of exceptional grounds for exemption from liability in Article 279-3 of the CUAO, the above category of persons is in a more unfavorable position than other subjects of administrative offenses. Although the general ground for exemption from administrative liability set out in Article 22 of the CUAO, which is the insignificance of an act, does not contain any restrictions on its application to automatically recorded offenses, the impossibility of its implementation is due to the specifics of the provisions of Articles 33, 268, 280 of the CUAO. The author formulates proposals for improving the legal regulation of application of Article 22 of the CUAO to offenses in this area, which will form the basis for further developments.
Equality of the Unborn Child and Women in Rights: A Constitutional Dilemma of Liberal Societies
Authors: Horbachevska Tamara
Published: March 2023

The article examines the problem of determining the constitutional status of an unborn child (human embryo) and the possibility of implementing his or her legal protection equal to that provided for a person after birth.The main object of analysis is the decision K 1\20 of the Constitutional Tribunal of the Polish Republic, adopted in October 2020, which recognized the unconstitutionality of legislative provisions on the possibility of terminating pregnancy (conducting abortion) in case of detection of severe andirreversible lesions of the fetus, or incurable disease of the embryo.The author carries out a legal analysis of the decision and attempts to outline the philosophy of law and constitutional issues regarding the determination of the legal status of the embryo, the volume of rights, and their relation with the right of a woman to private life in situations when they intersectand protection of one right excludes the protection of another.The author appeals to Herbert Hart’s concept of “positive morality” and his opinion that society cannot strive for a single moral goal or value that makes compromises necessary. Within this article, three subsections are presented that are important for the establishment of issues in responding to the questions. The first part offers the analysis of the decision of the Tribunal and the main legal provisions that influenced its formation. The second part represents a view of whether the prohibition to terminate pregnancy on the grounds of detection of severe and irreversible lesions of the fetus, or incurable disease of the embryo is permissible. The third part involves understanding the general philosophical issues of attributing abortions to so-called “complex cases” and basic views on how to solve such cases in the legal field.
COMPARANDO A EFICIÊNCIA ANALÍTICA DAS TÉCNICAS FTIR, UV-VIS, CLAE-DAD E ESI(+)MS NO ESTUDO DE CORANTES ALIMENTARES
Authors: Lyrio Marcos , Debona Danieli , Conceição Nathália , Gomes Francisco , Pereira Alan , Frizzera Henrique , Reis Jessica , Grecco Taila , Pires Bruna , Lacerda Jr. Valdemar , Castro Eustaquio , Isidoro Marsele , Filgueiras Paulo , Romão Wanderson
Published: March 2023

COMPARING THE ANALYTICAL EFFICIENCY OF FTIR, UV-VIS, CLAE-DAD AND ESI(+)MS TECHNIQUES IN THE STUDY OF FOOD DYES. Food additives are chemical substances added to improve organoleptic characteristics, in this context, there are several synthetic dyes, such as sunset yellow, tartrazine, erioglaucine, allura red, indigo carmine, and new coccine, that can also be identified through different analytical techniques such as infrared spectroscopy, UV-Vis spectrophotometry, high performance liquid chromatography with diode array detector and mass spectrometry. Therefore, the objective of this work was to compare methods developed for different analytical techniques, in order to identify the one that presents greater efficiency in certain applications. For this, the patterns of the dyes were analyzed, as well as their mixtures and foods that had them. As a result, the CLAE-DAD presents excellent selectivity and linearity of the calibration curves, but it presents higher LD and LQ values when compared to the UV-Vis, in turn the infrared provides information regarding functional groups and bonds. Mass spectrometry showed great capabilities in identifying the molecular formula and better selectivity in the absence of the erioglaucine dye. It is not feasible to indicate the best or worst analytical approach, but it is possible to point out which one is more suitable for each application. Regarding the quantification capacity, chromatography and UV-Vis are good alternatives, but in mixtures containing more than one dye, CLAE-DAD is more suitable due to the better selectivity. Regarding the identification capacity, mass spectrometry, especially FT-ICR MS, is the most appropriate technique to propose molecular formulas due to its high resolution and mass accuracy. The advantage of FTIR was the easier sample preparation, being able to analyze the dyes in the solid state.
Reseña de Sevilla Vallejo, S. (Coord) (2021) El proceso de Enseñanza y Aprendizaje. Hacia Una Vinculación Entre Tecnología Y Pedagogía. Reseña de Sevilla Vallejo, S.
Authors: Fidalgo-Suárez Natalia
Published: March 2023

La reseña trata de ofrecer una visión objetiva sobre los diferentes estudios de varios autores, quienes valoran la realidad edorte fundamental para el proceso de enseñanza y aprendizaje, basado en una unión eterna entre las dos corrientes, válidas en la medida que pueden favorecer a la comunidad educativa en su conjunto.tiva de una manera innovadora e inspiradora que puede aumentar la calidad de vida de la enseñanza, de docentes y alumnos.
Este trabajo enfoca su tarea en el análisis de estos estudios desde una visión también innovadora y basada en la unión entre lo mejor que ha dejado la enseñanza tradicional y los nuevos aportes de las investigaciones actuales.
El objetivo reside en crear un vínculo que permita percibir nuevas formas de aplicar los conocimientos, sin desdeñar todo aquello que ha sido un aporte fundamental para el proceso de enseñanza y aprendizaje, basado en una unión eterna entre las dos corrientes, válidas en la medida que pueden favorecer a la comunidad educativa en su conjunto.
Inhibition of Neuromyelitis Optica Immunoglobulin G Binding to Aquaporin-4
by the Small Molecule Blocker Melanthioidine
Authors: Xu Huijing , Gong Yushuang , Jiao Yang , Guo Jian , Zhao Ling , Yang Juechen , Tong Haibin , Sun Meiyan , Li Miao
Published: March 2023

Background:

Neuromyelitis optica (NMO) is a severe neurological demyelinating autoimmune disease
affecting the optic nerves and spinal cord. The binding of neuromyelitis optica immunoglobulin G (NMO-
IgG) and aquaporin-4 (AQP4) on the surface of astrocytes in the serum and cerebrospinal fluid is the main
pathogenesis of NMO. Currently, therapeutic strategies for NMO include a reduction of the secondary inflammation
response and the number of NMO-IgG, which can only alleviate clinical symptoms rather than fundamentally
preventing a series of pathological processes caused by NMO-IgG binding to AQP4.

Objective:

The purpose of this study was to investigate the blocking effect of melanthioidine on the binding of
NMO-IgG to AQP4 and its potential cytotoxicity.

Methods:

The current study developed a cell-based high-throughput screening approach to identify a molecular
blocker of NMO-IgG binding to AQP4 using the Chinese hamster lung fibroblast (V79) cells expressing M23-
AQP4. By screening ~400 small molecules, we identified melanthioidine with blocking effects without affecting
AQP4 expression or its water permeability.

Results:

Melanthioidine effectively blocked the binding of NMO-IgG to AQP4 in immunofluorescence assays
and reduced complement-dependent cytotoxicity against both NMO-IgG/complement-treated Fischer rat thyroid-
AQP4 cells and primary astrocytes. The docking computations identified the putative sites of blocker binding
at the extracellular surface of AQP4.

Conclusion:

This study serves as proof of a potential NMO therapy by using a small-molecule blocker to target
NMO pathogenesis.
Clinical Usefulness of Ultrasound Elastography in Colonic Diseases: A Narrative
Review
Authors: Qiu Zhongxian , Zheng Ruoting , Lin Jiawei , Li Jiafan , Zhai Yuxia
Published: March 2023

Ultrasound elastography is an innovation of ultrasound technology that has developed since the 1990s. It has been successfully applied for many organs, such as the thyroid, breast, liver, prostate, and muscle systems, providing qualitative and quantitative information about tissue stiffness for clinical diagnoses. For colorectal tumors, ultrasound elastography can distinguish colon adenoma from colon adenocarcinoma and predict the chemotherapeutic effects of colon cancer by monitoring the stiffness changes of cancer tissue. In Crohn’s disease, ultrasound elastography helps assess the stages of the course and guides further treatment strategies. Compared with colonoscopy, ultrasound elastography frees patients from the fears of uncomfortable procedures and enables operators to comprehensively observe the bowel wall and the surrounding structures. In this review, we introduced the principles and the pathological basis of ultrasound elastography and compared the diagnostic efficacies of colonoscopy with colonic ultrasound elastography. Meanwhile, we summarized the ultrasonography of colonic diseases and reviewed the clinical usefulness of ultrasound elastography in colonic diseases.
Current Landscape on Development of Phenylalanine and Toxicity of its
Metabolites - A Review
Authors: Bose Samrat , Mandal Shirsendu , Khan Rajesh , Maji Himangshu Sekhar , Ashique Sumel
Published: March 2023

Phenylalanine, an essential amino acid, is the "building block" of protein. It has a tremendous
role in different aspects of metabolic events. The tyrosine pathway is the prime one and is typically used
to degrade dietary phenylalanine. Phenylalanine exceeds its limit in bodily fluids and the brain when the
enzyme, phenylalanine decarboxylase, phenylalanine transaminase, phenylalanine hydroxylase (PAH) or
its cofactor tetrahydrobiopterin (BH4) is deficient causes phenylketonuria, schizophrenia, attentiondeficit/
hyperactivity disorder and another neuronal effect. Tyrosine, an amino acid necessary for synthesizing
the pigments in melanin, is produced by its primary metabolic pathway. Deficiency/abnormality in
metabolic enzymes responsible for the catabolism pathway of Phenylalanine causes an accumulation of
the active intermediate metabolite, resulting in several abnormalities, such as developmental delay, tyrosinemias,
alkaptonuria, albinism, hypotension and several other undesirable conditions. Dietary restriction
of the amino acid(s) can be a therapeutic approach to avoid such undesirable conditions when
the level of metabolic enzyme is unpredictable. After properly identifying the enzymatic level, specific
pathophysiological conditions can be managed more efficiently.
The Zebrafish Model as a New Discovery Path for Medicinal Plants in the Treatment of Parkinson’s Disease
Authors: Chahardehi Amir Modarresi , Hosseini Yasaman , Mahdavi Seyed Mohammad , Naseh Iman
Published: March 2023

Parkinson's disease (PD) is one of the most frequent degenerative central nervous system
disorders affecting older adults. Dopaminergic neuron failure in the substantia nigra is a pathological
sign connected with the motor shortfall of PD. Due to their low teratogenic and adverse effect potential,
medicinal herbs have emerged as a promising therapy option for preventing and curing PD and
other neurodegenerative disorders. However, the mechanism through which natural compounds provide
neuroprotection against PD remains unknown. While testing compounds in vertebrates such as
mice is prohibitively expensive and time-consuming, zebrafish (Danio rerio) may offer an appealing
alternative because they are vertebrates and share many of the same characteristics as humans.
Zebrafish are commonly used as animal models for studying many human diseases, and their molecular
history and bioimaging properties are appropriate for the study of PD. However, a literature review
indicated that only six plants, including Alpinia oxyhylla, Bacopa monnieri, Canavalia gladiate, Centella
asiatica, Paeonia suffruticosa, and Stachytarpheta indica had been investigated as potential PD
treatments using the zebrafish model. Only C. asiatica and B. monnieri were found to have potential
anti-PD activity. In addition to reviewing the current state of research in this field, these plants' putative
mechanisms of action against PD are explored, and accessible assays for investigation are made.
Molar Incisor Hypoplasia (MIH)
Authors: Bhaje Priyanka , Iyer Vidya , Jetpurwala Abdulkadeer
Published: March 2023

Developmental defects of enamel a commonly encountered condition in
both primary and permanent teeth enamel. Ameloblasts being highly specialized cells
are highly sensitive to a host of environmental factors. As a result, a large number of
factors can cause hypomineralization. Of the various hypoplastic and
hypomineralization defects affecting the enamel, this chapter focuses on a distinct
condition of hypomineralization involving mainly the molar and incisor teeth. 
The Benefit of Counselling to Pregnant Women with a History of Spontaneous Abortion: A Case Report
Authors:   Department of Midwifery Medicine Faculty, University of Brawijaya, Malang, Indonesia, Khusmitha Qatrunnada
Published: March 2023

Background: Abortion becomes a complication that can occur in pregnancy and cause psychological and physical distress. Spontaneous abortion can become trigger anxiety and depression during pregnancy. Midwifery who helps patients in perifer or rural areas need to concern about how to do early detection and counseling to reduce risk of psychological risk which can be elevated. Objective: This report aimed to evaluate the anxiety and depression state with a history of spontaneous abortion in their first pregnancy. Methods: This paper was a case report reporting a patient with a second pregnant condition. This patient has a history of spontaneous abortion in her first pregnancy. Evaluating process with Hamilton Anxiety Rating Scale (HAM-A) dan Hamilton Depression Rating Scale (HDRS) and follow-up after parturition period. Results: Decreasing scores on HAM-A and HAM-D after counseling helped the patient to release her anxiety and depression during pregnancy. The patient is more prepared about signs and symptoms when she feels uneasy and overwhelmed and protects herself from another distortion cognition from spontaneous abortion. Conclusion: Counselling had benefits to decrease anxiety and depression in pregnant women with a history of spontaneous abortion. Keywords: anxiety, depression, spontaneous abortion.
PERENCANAAN KAWASAN HUNIAN KOMUNAL SEMENTARA DENGAN KONSEP MULTI-FUNGSI DALAM PERSPEKTIF PENGEMBANGAN WILAYAH KOTA PALU
Authors: Anisa  , Saputra Ashar , Satyarno Iman
Published: March 2023

Gempa bumi 2018 di Kota Palu menyebabkan kerusakan fasilitas umum dan aset masyarakat, hal ini mengharuskan para korban mengungsi ke hunian sementara hingga rumah mereka selesai direkonstruksi atau memperoleh hunian baru. Problematika masyarakat menolak relokasi, masyarakat tidak nyaman tinggal di hunian sementara, hingga pembangunan fasilitas hunian sementara yang meningkatkan biaya pembangunan. Hal ini memecah fokus rehabilitasi dan rekonstruksi. Berdasarkan fenomena tersebut dapat disimpulkan bahwa dalam situasi darurat regulasi tidak lagi diprioritaskan, sehingga fasilitas penting seperti hunian sementara perlu dipersiapkan secara matang. Penelitian ini bertujuan merencanakan sistem fasilitas hunian sementara dengan konsep multi-fungsi. Pengumpulan data dilakukan dengan survey instansional, pengisian kuesioner, dan mengkaji pustaka. Penelitian ini dilakukan secara kuantitatif dengan menggunakan metode Analisis Hirarki Proses (AHP), dimana peneliti menggunakan kriteria dari 4 Stakeholder untuk menentukan lokasi alternatif yang cocok dikembangkan menjadi kawasan hunian komunal sementara. Penelitian ini juga mengkolaborasikan analisis klasifikasi tingkat bahaya dan klasifikasi kepadatan penduduk. Hasil dari penelitian ini menunjukkan bahwa kawasan hunian komunal sementara terdiri atas tiga hirarki yaitu Kecamatan Mantikulore sebagai Pusat hunian komunal sementara. Kecamatan Palu selatan, Kecamatan Tatanga dan Kecamatan Ulujadi, Kecamatan Palu Utara, dan Kecamatan Tawaeli akan menjadi Sub-pusat pelayanan hunian komunal sementara.  adapun Kecamatan Palu Barat dan Kecamatan Palu Timur menjadi kawasan terlayani.
Kata Kunci : huntara, hirarki pelayanan, multifungsi, Kota Palu
IDENTIFIKASI JEJARING EKOLOGI RUANG TERBUKA HIJAU KOTA BANDUNG
Authors: Nabilla Dina Adharina  , Triagung Aulia
Published: March 2023

Kota Bandung merupakan kota terbesar ke tiga di Indonesia. Pesatnya pembangunan menyebabkan tingginya kompetisi antara kebutuhan ruang untuk produktivitas dan ruang hijau yang memiliki peran dalam memberikan jasa ekosistem. Penyediaan RTH pada suatu kota telah ditetapkan oleh peraturan yang mana diturunkan ke dalam rencana tata ruang, yaitu 30% dari luas wilayah. Meskipun begitu, agar RTH mampu secara maksimal berperan memberikan jasa ekosistem dan berkontribusi dalam mewujudkan kota berkelanjutan, kuantitas RTH bukanlah hal utama. Terbentuknya jejaring ekologi RTH kini telah menjadi indikator penting dalam pengembangan RTH. Konsep ini menekankan terbentuknya jejaring dari keterkaitan satu RTH dengan RTH lainnya yang terhubung melalui jalur hijau. Berdasarkan hal tersebut, penelitian ini akan mengidentifikasi seberapa jauh jejaring ekologi RTH di Kota Bandung sudah terbentuk. Hasil analisis menunjukkan bahwa jejaring ekologi RTH belum terbentuk di Kota Bandung, analisis spasial menunjukkan hanya 13% RTH yang sudah terhubung. Hasil dari penelitian ini menekankan bahwa dalam penyediaan RTH tidak cukup hanya dengan melihat distribusi RTH secara kuantitas saja. Bagaimana satu RTH dan RTH lainnya terhubung dengan baik melalui jalur hijau seharusnya menjadi arahan kebijakan yang perlu ditekankan dalam penataan ruang perkotaan agar RTH dapat berperan maksimal dalam mewujudkan kota berkelanjutan.
Kata Kunci : Bandung, jejaring ekologi, kota berkelanjutan, ruang terbuka hijau.
Molecular Identification of Medicinal Plant, Polygonum posumbu from Manipur, India
Authors: Pukhrambam Premi Devi
Published: March 2023

Polygonum is an important genus of Polygonaceae and Polygonum posumbu is underutilized traditional medicinal plant whose leaves are extensively used as an antipyretic and dyspepsia agent in Manipur, India as well as a spice in India, Japan, Nepal, China, South Korea, Philippines and Thailand. P. posumbu is commonly known as Phak-pai in Manipur. DNA barcode based molecular characterization technology for species identification has been recognized as a reliable tool for plants but the selection of suitable universal marker is still under discussion. The main aim of the study is to identify the Polygonum posumbu sample from Manipur, India using DNA barcode method. In the present study, Polygonum posumbu samples were collected from a local farmer in Awang khunou, Imphal West, Manipur, India which was taxonomically identified. To assess the molecular species identification, Internal Transcribed spacer (ITS) marker system was employed and the primer’s pair used were covered the internal transcribed spacer 1, 5.8S ribosomal RNA gene and internal transcribed spacer 2 complete sequence. Phylogenetic tree was constructed for the studied sample with the sequences of the 9 species retrieved from the GenBank in order to show the relationships among the samples. The result shows that the ITS marker-based DNA identification method successfully characterized the Polygonum posumbu species. The information of ITS marker-based identification of Polygonum posumbu from Manipur, India, will enhance our knowledge in better understanding the medicinal properties of this plant.
Potential Application of the Objective Regression Regressive Methodology
Authors: Duarte Rigoberto Fimia
Published: March 2023

The possibility of having a methodology that allows the modeling and prediction, in the short, medium and long term, of biological, social and natural disaster processes and/or phenomena is something great. The objective of the research consisted in demonstrating the potentialities and real capacity of application of the methodology of the Regressive Objective Regression (ROR) in the different fields and branches of scientific research. In the ORR methodology, in a first step, dichotomous variables DS, DI and NoC are created. Then, the module corresponding to the Regression analysis of the SPSS statistical package (ENTER method) is executed, where the predicted variable and the ERROR are obtained; subsequently, the autocorrelograms of the ERROR variable are obtained, paying attention to the maximum of the significant partial autocorrelations, and the new variables are calculated according to the significant Lag of the PACF. Finally, these regressed variables are included in the new regression in a process of successive approximations until a white noise is obtained. Wide possibilities of modeling and forecasting in the short, medium and long term, which go beyond the modeling of infectious entities of parasitic and viral etiology, Acute Respiratory Infections, Acute Bronchial Asthma crises, forecasting of extreme meteorological disturbances, prediction of latitude and longitude of earthquakes, modeling of climatic variables, and even the own electric consumption of a municipality, province and nation. The ROR methodology has demonstrated potential and real capabilities of application in dissimilar fields and branches of science, so it is a novel contribution to the science of modeling and forecasting of variables to know the future, as well as the impact that different variables contribute to an event or phenomenon, and being universal, it can be applied anywhere in the universe.
Изменение параметров МДП-структур с соединениями редкоземельных элементов в условиях повышенной влажности
Authors: Шалимова М.Б. , Белянина И.В.
Published: March 2023

The properties of MIS structures with yttrium, neodymium, samarium fluorides on germanium, neodymium and samarium fluorides on n and p silicon substrates, as well as Al-Y2O3-nSi, Al-Y2O3-pSi structures under conditions of high ambient humidity were studied. Additionally, the structures were exposed to an electric field of ~ 0.5 – 4 MV/cm. For MIS structures with films of yttrium, neodymium, and samarium fluoride on germanium, as well as neodymium and samarium fluoride on n and p silicon substrates, a clear increase in the maximum specific capacitance with increasing relative humidity of the medium is observed. It has been found that the incorporation of water into the structure of the REE film fluorides studied in this work is sorption and does not cause irreversible changes in the dielectric film at the studied temperatures.
Whole genome sequence analyses of Indonesian isolates SARS‐CoV‐2 variants and their clinical manifestations
Authors: Lie Elnora Listianto , Hermawan Tedi Dwi Fauzi , Audah Kholis Abdurachim
Published: March 2023

The SARS‐CoV‐2 virus has been the cause of the global pandemic since the end of 2019. Since then, the virus has mutated to create different types of variants with numerous effects on those infected. This has complicated human intervention for prevention. Indonesia was heavily affected by the pandemic, specifically from May to August 2021, and as a country has recorded many distinct isolates. Thus, characterization of the virus strains from Indonesia is important. GISAID, NCBI BLAST, and MAFFT version 7 were used. There were 9,488 isolates in Indonesia as of November 2021, with the majority including the Delta variant. While most of the isolates have mutations common to those from other countries, there are some atypical ones, such as mutation V1264L in the Delta variant that was suspected to play a role in worsening the pandemic. The Delta variant had the most mutations in the spike protein when compared to the Alpha and Beta variants, giving it important roles in infectivity and vigorous entry into cells, with some general clinical manifestations like fever and sore throat; however, the severity of the Delta variant is attributable to its rapid growth. This is why, from May to November 2021 in Indonesia, cases of the Delta variant rocketed, unlike the other variants.
Unity in Diversity: Religion Cum Language Argument for African Multiculturalism
Authors: Ukpong (Ph.D) Dominica E. , Nyah (Ph.D) Peter
Published: March 2023

Multiculturalism is a relatively new and engaging area of scholarship, and has been viewed variously from an interdisciplinary point of view especially as having more problems than it can resolve. Africa is also known as a hub for multiculturalism with a handful of ethnic and tribal groups. Despite the problems associated with multiculturalism such as diversity in language and cultural beliefs, this work attempts to x-ray the concept of “unity in diversity” from a religious cum language basis that supports the argument that multiculturalism from a traditional African point of view, is very beneficial, important and helpful rather than its negative perception. The method employed in the study is critical analysis.
En villkorad gemenskap. Hbtq, sexualitet och kristen frikyrklighet
Authors: Carlström Charlotta
Published: March 2023

Homosexuality, bisexuality, transgender and queer have long been a sensitive topic in Christian churches. As society has changed, some denominations have become increasingly affirming, while others see the changes as incompatible with Christian values. A Conditional Community is based on in-depth interviews with 29 lgbtq Christians and is the first Swedish scientific study on the subject. Using a phenomenological approach, the author investigate how sexuality, intimacy and faith are experienced by the interviewees and how their Christian identity interacts with their identity as lgbtq people. A Conditional Community is aimed at teachers, researchers and students in fields such as religious studies, sexology, gender studies and psychology. The book is also of interest to professionals who require knowledge on the subject, such as pastors and therapists. Furthermore, it can serve as a basis for discussions and reflection on faith, sexuality and lgbtq in the Free Church contexts.
PROFISSIONAIS DE APOIO NA CONCEPÇÃO DE PROFESSORAS DA SALA REGULAR
Authors: Batista Estabile Carolina , Fusca Machado Cordeiro Aliciene
Published: March 2023

A educação especial e inclusiva vem sendo discutida no Brasil e no mundo há muitos anos. Foram criados diversos documentos a fim de promover a inclusão aos alunos público-alvo da educação especial. Atualmente, com base em leis, declarações e diretrizes, os estudantes que não realizam as atividades de alimentação, higiene e locomoção de forma independente possuem o direito de ter um profissional de apoio para auxiliá-los. Dessa forma, a presente pesquisa teve como objetivo compreender a concepção de professoras da sala regular sobre o trabalho dos profissionais de apoio. Assim, ocorreu a análise de dados de entrevistas, realizadas de forma online e individual, com seis professoras que trabalham e/ou já trabalharam com profissionais de apoio a partir do ano de 2019 até o momento da pesquisa. Trata-se de uma pesquisa de cunho qualitativo e exploratório cujos dados obtidos foram transcritos e analisados com base na metodologia da Análise de Conteúdo de Bardin (2016) e Franco (2008). Os resultados mostraram que, independentemente do tempo em que as professoras estão atuando na educação, a concepção referente ao trabalho dos profissionais de apoio foi semelhante, compreendendo que os profissionais de apoio, além de realizarem atividades de vida diária, também auxiliam em questões pedagógicas dos alunos público-alvo da educação especial.
CONCEPÇÕES E VIVÊNCIAS DA GESTÃO EM ESCOLA CONFESSIONAL
Authors: Degrandis Fernando
Published: March 2023

Entre os conceitos expressos nos documentos da instituição escolar, aquilo que o gestor compreende e o que de fato acontece na escola confessional, há dinâmicas complexas. Estes processos são coerentes e colaboram para a aprendizagem dos discentes? Este é o questionamento central deste estudo, que visa analisar como a prática de gestores de escolas confessionais influenciam nas aprendizagens de estudantes. Este texto é parte integrante da tese do mesmo autor. A pesquisa qualitativa, de caráter explicativo, foi realizada ao longo de três anos (2015 – 2017) em duas escolas do Rio Grande do Sul, através de aplicação de questionários a estudantes, professores e gestores. Ainda compondo a pesquisa, foram realizadas leituras de documentos da rede de colégios e outros aportes bibliográficos. Os dados dos questionários foram categorizados através de um software. A compreensão de gestão, que supera e engloba a perspectiva administrativa, é fundamental para acompanhar procedimentos, estudantes e educadores. As compreensões dos gestores e dos documentos indicam uma coerência no que tange a uma aproximação maior do conceito de gestão, bem como um olhar sistêmico e integral, tanto das pessoas como dos processos. Contudo, isto está presente na intencionalidade dos gestores e pouco em suas estratégias, o que também revela uma cultura e um ambiente educativos.
O USO DA METODOLOGIA STEAM EM SALA DE AULA NA DIMENSÃO DA EDUCAÇÃO AMBIENTAL NO CURRÍCULO: reflexões iniciais
Authors: Lemos Bergamaschi Christyan , A. C. Lima Gonçalves Mariana , Pires Campos Carlos Roberto , Lyra Silva Passos Marize
Published: March 2023

A educação na sociedade contemporânea se apresenta com inúmeros desafios, intensificados durante a pandemia do COVID-19, com a inserção emergencial das tecnologias digitais. É neste contexto que este estudo analisa a proposta do uso da metodologia STEAM (acrônimo em inglês para as disciplinas Ciência, Tecnologia, Engenharia, Artes e Matemática) vinculado ao design thinking, de modo contextualizado, ao contemplar a dimensão da educação ambiental no currículo, propondo-se a responder: como a aplicação do STEAM vinculado ao design thinking pode contribuir para a abordagem interdisciplinar na sala de aula a partir de um tema socioambiental? As atividades desta pesquisa foram realizadas em cinco fases, com duas turmas dos sétimos anos do Ensino Fundamental e uma turma do doutorado em Educação em Ciências e Matemática, a partir de um problema socioambiental: o desaparecimento das abelhas no mundo. Para análise dos dados, utilizou-se a análise textual discursiva, que permitiu reconhecer o STEAM e o design thinking como processos que ampliam o interesse e a participação dos envolvidos, conduzindo-os para a discussão do problema, identificando caminhos possíveis. Também foram reveladas as fragilidades do currículo fragmentado da educação básica, o qual se distancia de um princípio básico da educação ambiental: a concepção da totalidade. Desse modo, a pesquisa problematiza a formação dos sujeitos no coletivo para uma transformação cultural no ambiente escolar e na sociedade contemporânea.
GESTÃO ESCOLAR E DESEMPENHO DOS ALUNOS: uma revisão de literatura em periódicos brasileiros (2001-2021)
Authors: Gino João Carlos , Paes de Carvalho Cynthia , Lopes Karina Carrasqueira
Published: March 2023

O presente artigo tem por objetivo estabelecer uma revisão de literatura em periódicos nacionais sobre as relações entre a gestão escolar e os resultados acadêmicos dos alunos nas últimas duas décadas. A metodologia da pesquisa adotou a abordagem qualitativa, utilizando os procedimentos de levantamento bibliográfico e revisão de literatura, tendo em vista mapear o atual estado do conhecimento sobre o tema, assim como levantar as abordagens metodológicas utilizadas pelos autores nos estudos. O estudo revelou a ainda carente produção acadêmica brasileira acerca da relação entre a gestão escolar e os resultados acadêmicos dos alunos, em contraste com o cenário internacional de pesquisas sobre o tema. Observamos que temas como a liderança escolar e o clima escolar ainda são mais recorrentes em autores estrangeiros e de fora da área da Educação, mesmo em periódicos nacionais. Os artigos nacionais trouxeram alguns resultados em comum com relação a fatores intraescolares que fazem diferença no desempenho acadêmico dos alunos: a liderança pedagógica da gestão escolar, a complexidade da gestão escolar, a percepção do clima escolar, a adequação da infraestrutura física e pedagógica, e a apropriação dos resultados das avaliações externas pelas escolas.
APRESENTAÇÃO DO DOSSIÊ "GESTÃO NA EDUCAÇÃO: POLÍTICAS E PRÁTICAS"
Authors: De Souza Waldhelm Andrea Paula , Pedrosa de Camargo Flávia , Da Conceição de Lima Carla
Published: March 2023

Apresentação
¿Existen injusticias hermenéuticas en el derecho?
Authors: Herdy Rachel , Castelliano Carolina
Published: March 2023

Este artículo discute la aplicación del concepto de injusticia hermenéutica (Miranda Fricker, 2007) en contextos judiciales. Se argumenta que la aplicación de este concepto para capturar los problemas de la ininteligibilidad judicial de experiencias marginadas no es tan claramente discernible. Hay un obstáculo para su aplicación al derecho cuando se analizan los elementos que, según Fricker, componen la definición de injusticia hermenéutica. Más específicamente, su carácter puramente estructural no encaja muy bien con una perspectiva realista de la actividad de interpretación judicial. Desde esa perspectiva, los intérpretes judiciales tienen un papel decisivo en la evitación o creación de lagunas hermenéuticas. Más allá del componente agencial de la injusticia hermenéutica judicial, se argumenta que la intencionalidad del intérprete judicial es, en cierto sentido, peculiar –lo que es particularmente evidente en los casos penales–. La conclusión de este artículo es que la injusticia hermenéutica judicial desdibuja la línea entre las dimensiones estructural y agencial de la injusticia hermenéutica, de modo que la definición de Fricker es solo parcialmente útil para el derecho.
An Overview on the Worlds Dead Liest Poison (Palytoxin and its Analogs)
Authors: Abuaziz Suliman S S , Pavani Suraboyina , Singh Kanchan
Published: March 2023

Abstract: Palytoxin is a marine toxin found originally in soft corals Palythoa species of the Pacific Ocean. It is a thermostable, non-protein, coronary vasoconstrictor that leads to death by diminishing the supply of O2 to the Myocardium. Several analogs of PTX or PTLX such as Ostreocin-D, Ovatoxin are found in several dinoflagellates and other marine species such as Crabs (Demania reynaudii) and Smoked Fishes (Decapterus macrosoma) found in same ecological regions. Toxicological studies of PTX showed low lethal dose values in different mammals revealing the acute toxicity due to different routes of exposure. On exposure to PTX, symptoms such as Rhabdomyolysis (high dose), Na+- K+ pump and heart failure & other symptoms including abdominal cramps, vomiting, bradycardia, etc. are seen in Pescatarians. There is no particular antidote for the PTX compounds, but these compounds can be neutralized by the household bleach solution. Activated Carbon absorbed 99.7% of palytoxin in aquarium waters. In this paper, we review the current knowledge on Palytoxin & its analogs. In recent years, many methodologies have been described for the development of new techniques for the detection of palytoxin based on LC-MS/MS and a bio-technique Immunoassay.
Network Security Key Areas of IoT and IIOT- with Connected Devices Privacy and Security
Authors: Kotaiah Dharavath , Kiran Chitti Ravi
Published: March 2023

Abstract: With the accelerating pace of technological advancement, demand for IoT app development is at an all-time high. Statistic predicts that $1.1 trillion will be spent globally on IoT. (approx.).Modern IoT apps and solutions will unquestionably become more popular as a result of this. Who will get the newest item into consumers' hands first among manufacturers is still a point of contention. Companies can profit much from IoT app development, but one of the key considerations is security. This post focused on IoT security issues and solutions. IoT solutions can be implemented by businesses of any size and in any industry to boost productivity and customer satisfaction. This article all about the security of IoT and IIoT how to overcome them. Organizations regardless of industry and size can make IoT solutions a part of their business to increase customer satisfaction and efficiency.
A Review of the Catalysts Used in Propane Ammoxidation Reaction to Produce Acrylonitrile
Authors: Garg Pulkit
Published: March 2023

Abstract: Background: Various catalysts were studied to synthesize acrylonitrile via propane ammoxidation. The catalysts used for this process can be categorized as antimony-based catalysts, molybdenum-based catalysts, zeolites, nitride material catalysts, and other catalysts. The catalyst which was proved to be an efficient catalyst among all other catalysts is the mixed metal oxide catalyst MoVNbTe due to its high selectivity and yield.