bluuebunny/crossref_metadata_2025 huggingface dataset:
In dogs with snakebites does the use of antimicrobials compared to no antimicrobials reduce incidence of wound infection?
Authors: Ballman Megan , Messina Davide
Published: July 2023

PICO question
In dogs with snakebites does the use of antimicrobials compared to no antimicrobials reduce incidence of wound infection?
 
Clinical bottom line
Category of research
Treatment.
Number and type of study designs reviewed
Seven case series.
Strength of evidence
Weak.
Outcomes reported
Three studies looked at the incidence of wound infection in envenomated dogs, three compared antimicrobial use to mortality and one compared other outcomes, such as time in hospital. The incidence of wound infection was low in the studies and overall antimicrobials seemed to have no significant effect on outcomes such as survival or wound infection. Therefore, the routine use of antimicrobials for snakebite treatment is not supported by the results, however further studies are required to provide conclusive evidence.
Conclusion
There is currently insufficient evidence from literature to either support or reject the use of antimicrobials in the treatment of snakebites.
 
How to apply this evidence in practice
The application of evidence into practice should take into account multiple factors, not limited to: individual clinical expertise, patient’s circumstances and owners’ values, country, location or clinic where you work, the individual case in front of you, the availability of therapies and resources.
Knowledge Summaries are a resource to help reinforce or inform decision making. They do not override the responsibility or judgement of the practitioner to do what is best for the animal in their care.
"Essential oil Composition, Antioxidant and Antibacterial Activities of Jatropha tanjorensis (Euphorbiaceae)"
Authors: Okpala Ejike Onwudiegwu
Published: July 2023

Background: Jatropha tanjorensis (Euphorbiaceae) leaves are traditionally used for the treatment of diabetes and also, possess antibacterial potential. The chemical composition, antioxidant and antibacterial activities of the oil were investigated. The essential oil (EO) was obtained by hydro-distillation method and characterised using gas chromatography-mass spectrometry (GC-MS). The antioxidant activity was investigated using 2, 2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging technique and antibacterial activity of the volatile oil was evaluated against 6 strains of bacteria: Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumonia, Staphylococcus aureus, Bacillus subtilis and Salmonella typhi, using broth dilution method.
Robot Path Estimation from Odometry Measurements: Loop Closure Based on Autocorrelation
Authors: Dermatas Evangelos
Published: July 2023

The problem of estimating the Robot path when covering closed trajectories using only the wheels odometry information is met in indoor low-cost robotic applications. Random and systematic errors related to the measured angle accuracy, deviations from the desired path and wheel radius in robot turns, introduced significant errors in the process of estimating the actual path. In this paper the autocorrelation function is used for accurate estimation of the path periodicity and to reconstruct the robot path. Real-life experiments using a real robot showed minor differences between the estimated and the predicted path.
INDEKS KEPUASAN MASYARAKAT TERHADAP PROGRAM CSR BUJUR BERSTAMINA: BUDIDAYA JAHE MERAH
Authors: Yuliani Rahma , Mubarak Zaki , Arifah Arifah , Norlena Norlena
Published: July 2023

Corporate social responsibility (CSR) as a community empowerment program that can improve the community's economic level. PT. DPPU Pertamina Syamsudin Noor is implementing a CSR program that focuses on red ginger nuns. This study aims to measure the community satisfaction index (IKM) for the CSR programs that have been implemented. This research is a quantitative research using 10 elements of question indicators. The research population is all the people in Sidomulyo Village 1 RT. 02 and RT. 03, Guntung Payung Village, Banjarbaru City. The sample in this study was taken using a simple random sampling technique. The results showed that the IKM score was 3.39, with a conversion value of 84.75. Based on this value, it was concluded that the IKM from the implemented CSR program was in the very good category.
Validitas Virtual Lab Biologi Berbasis Pendekatan Saintifik pada Materi Struktur dan Fungsi Jaringan Tumbuhan
Authors: Fitriani Dessy Rahmadita , Amintarti Sri , Riefani Maulana Khalid
Published: July 2023

The pandemic that has occurred around the world has affected various areas of life, including education. Learning in schools has been directed at distance learning, including biology practicum activities in the laboratory. Teachers are required to innovate and create interactive media. One of the interactive learning media that can connect the subject and object of learning is a virtual lab. Learning media must be suitable for use in the learning process. This study aims to describe the feasibility of a virtual lab based on a scientific approach on the structure and function of plant tissue. Research and development carried out using the Borg & Gall (1983) model, until the main product revision stage. The feasibility of learning media resulted from expert validation and user readability tests. Expert validation shows that the virtual biology lab based on a scientific approach is a very valid category. The readability test in a virtual biology lab based on a scientific approach showed a very good category. The virtual lab learning media based on a scientific approach to the material on the structure and function of plant tissue can be used independently or guided in distance learning.
Kepraktisan E-handout “Lingkungan Lahan Basah Sekitar” dalam Melatihkan Keterampilan Berpikir Kritis
Authors: Wahyunah Wahyunah , Winarti Atiek , Badruzsaufari Badruzsaufari
Published: July 2023

Critical attitude is born from critical thinking skills in the neighborhood (surrounding environment) and the daily life of the individual. Critical thinking skills can be trained in the learning process by using appropriate learning strategies and resources. One of the learning resources that can be used to practice critical thinking skills is a contextual electronic handout (e-handout). This study aims to describe the practicality of the e-handout “Surrounding Wetlands Environment” to practice critical thinking skills. Assessment of the practicality of the e-handout through one-on-one evaluation and small group evaluation. The research subjects were 5 students of Biology Education at Universitas Lambung Mangkurat (one-on-one evaluation) and 5 other students (small group evaluation). The data collection instruments used were readability test questionnaires, implementation test questionnaires, student response questionnaires, and critical thinking skills measurement activity sheets. The results showed that the e-handout "Surrounding Wetlands Environment" is very practical to practice critical thinking skills.
Validitas Soal pada Asesmen Kompetensi Minimum Materi Ekologi SMA Kelas X
Authors: Sensus Marsi , Arifin Kasman , Munir Asmawati
Published: July 2023

Minimum Competency Assessment is an assessment of the basic competencies needed by students in developing their own capacity and positive participation in society. The assessment components measured are reading literacy and numeracy literacy. Most students in SMA and SMK are not ready with the Minimum Competency Assessment. Students assume that the questions tested are not in accordance with the learning material. Teachers must be able to familiarize students with literacy and make literacy questions correctly. This study aims to analyze the product of the Minimum Competency Assessment instrument developed. This type of research is research and development using 4D models. Validation was carried out on reading literacy questions, numeration related to high school ecology material for Class X. The results show that the number of items in the reading literacy question, numeracy question, choice question, and matchmaking question include the category of quite suitable to very suitable in terms of the number of question items. The number of questions in the complex multiple-choice section including the appropriate category (100%). Based on the validator's assessment, the Minimum Competency Assessment items developed are sufficient in accordance with the Basic Competencies of Class X High School Ecology Materials.
Sintasan dan Pertumbuhan Larva Ikan Gabus (Channa striata) Diberi Artemia yang Diperkaya Vitamin A
Authors: Akbar Junius
Published: July 2023

The survival rate of snakehead fish (Channa striata) is low. Provision of natural food during the survival phase and growth of snakehead fish larvae is very important. Artemia is a natural food for freshwater and marine fish larvae which has high nutritional value, but lacks vitamin A. Enrichment techniques are needed to increase the nutritional value of Artemia. The aim of this study was to compare survival rates, growth rates of snakehead fish larvae fed Artemia feed enriched with vitamin A. Snakehead fish were reared for 16 days and given Artemia enriched with vitamin A (with 1,000 IU/L, 2,000 IU/L, and 3,000 IU/l. The results showed that treatment had no significant effect on survival rate (58.33-98.33%), but had a significant effect (P>0.05) on total weight growth and feed conversion ratio (1.062-4.23 gram and 3.581- 5.100 grams), and had a very significant effect (P>0.01) on total length growth (1.036-1.256 cm). The best dose for maintenance of snakehead fish larvae is Artemia enriched with vitamin A with 3,000 IU/L.
Respon Pertumbuhan Setek Batang Rosmarinus officinalis L. Terhadap Variasi Media Tanam Dan Konsentrasi Air Kelapa Sebagai Zat Pengatur Tumbuh Alami
Authors: Naufal Zulfikar Alvin , Dewanti Felicitas Deru , Sutini Sutini
Published: July 2023

Rosemary is one of the aromatic herb plants that is known to challenges in its seed production because the propagation of rosemary still relies on seed germination with low germination rates. To overcome this. This research aims to determine the growth response of rosemary stem cuttings to the application of Plant Growth Regulator (PGR) in the form of coconut water, variations in growing media, and their interaction. The study was conducted using a Completely Randomized Design with the variation of growing media and different concentrations of coconut water PGR solution. The experiment was conducted in a greenhouse, with a total of 15 treatment combinations repeated 3 times. The observed parameters included root length, number of roots, and number of shoots, with observations made every two weeks. The results showed that the combination of coconut water concentration and variation in growing media significantly interacted with the growth parameters, namely root length and number of roots. Additionally, individual factors such as the mixed soil and rice husk charcoal growing medium and 75% coconut water concentration separately had a significant effect on the number of sprouts at 42 and 56 days after planting.
Inventarisasi Tanaman Bernilai Ekonomi Sebagai Obat Tradisional Suku Bugis di Kabupaten Bone Sulawesi Selatan
Authors: Syamsuri Syamsuri , Yusal Muh. Sri , Alang Hasria
Published: July 2023

Ethnoeconomics is a branch of ethnobotany that studies the role of plants that have economic value, one of which is as traditional medicine by an ethnic group or ethnomedicine. The purpose of this study was to inventory traditional medicinal plants of the Bugis tribe in South Sulawesi as ethnomedicines. The research was conducted from November 2022 to January 2023 in Pallae Village, Cenrana District, Bone Regency, South Sulawesi. This type of the research  was qualitative descriptive, to describe the use of plants as traditional medicine. Data collection techniques through interviews, observation, and literature studies. Respondents were selected by purposive sampling. Research data were analyzed descriptively and compared with scientific data or scientific data. Based on the results of the study, the types of plants used as traditional medicine by the Bugis tribe in the research location were noni, belimbing wuluh, sidaguri, areca nut, moringa, broken glass, cat's whiskers, ginger, bangle, turmeric, lemongrass, aloe vera, betel, tobacco, soursop and bagore. Plant organs used as medicine are fruit, leaves, rhizomes, and mucus
Kepadatan Populasi Cacing Tanah (Haplotaxida: Lumbricina) Sebagai Bioindikator Kesuburan Tanah Di Kebun Nusantara PT. Cinquer Agro Nusantara
Authors: Imaniar Lisana Husna , Arseliana Lily , Maretta Gres , Darmawan Andy , Nurhayu Winati , Sari Dian Anggria , Nanda Muhammad Zulhiyadi
Published: July 2023

Earthworms (Haplotaxida: Lumbricina) are bioindicators of soil fertility. Agricultural systems applied to an agricultural area can affect the presence of earthworms there. This study aims to determine the density of earthworms in plantations owned by PT. Cinquer Agro Nusantara with Agroforestry-Organic, Monoculture-Semiorganic, Polyculture-Organic, Monoculture-Organic, and farmer-owned plantations with Monoculture-Inorganic system. The plot is determined with line transect method and samples of earthworms are taken with hand sorting method. Data analysis was carried out with ANOVA and Post Hoc T-Test with Bonferroni correction. The results showed that the density of earthworms in pepper plantations with Agroforestry-Organic, Monoculture-Semi-organic, Polyculture-Organic, and Monoculture-Organic farming systems is significantly greater than pepper plantations with Monoculture-Inorganic farming system.
Parental Involvement in STEM Education: A Systematic Literature Review
Authors: Gülhan Filiz
Published: July 2023

STEM education has been a significant subject in the world and it has been studied by researchers. But parental involvement to STEM education hasn’t been on the agenda enough. In this study, findings were reached by examining 24 studies determined by literature review and PRISMA criteria. When analysis on the studies; it was concluded that there was an increase in 2021, the most in article type were written, they were mostly made in the USA, mostly primary school students were the subject, and the studies were mainly conducted in the survey model. It has seen that the subject of family participation in the STEM program (parent-child activities) is and their positively results frequently pointed. The positive effects of family career and their emotional characteristics on STEM success are frequently studied topics. In the theme of STEM activities at home, it was concluded that studies were conducted in which parents support STEM education mostly in terms of technology. Suggestions were made for performing STEM activities with the participation of families and investigating their effects.
Scaled Shaking Table Tests Simulating the Damage of the School Gymnasium in the 2016 Kumamoto Earthquake
Authors: Fujiwara Jun , Terazawa Yuki , Kishida Akiko , Nishimura Koshiro , Yamashita Tetsuo , Kumagai Tomohiko , Takeuchi Toru
Published: July 2023

The transverse out-of-plane response of the RC moment frame on the arena floor damaged a school gymnasium that was expected to function as a natural disaster shelter. It was composed of heavy RC substructure and a light steel roof, which partially collapsed, resulting in the facility's
permanent destruction in the 2016 Kumamoto earthquake. This study describes scaled shaking table tests that simulate out-of-plane response-induced damage to the RC moment frame of the school gymnasium during the 2016 Kumamoto earthquake and verifies the damage mechanism proposed by the previous
numerical simulation and the efficiency of a response control by the friction damper support. Furthermore, the study validates two methods for evaluating the response of the RC moment frame and the overall buckling strength of the roof truss member with semi-rigid joints.
Research on the Method of Simplifying Concrete Substructures of Suspen-Dome Prototype Structure in Shaking Table Test Scale Model
Authors: Zhao Zetao , Xue Suduo , Li Xiongyan
Published: July 2023

This paper proposed and studied the method of simplifying concrete substructures of the suspen-dome prototype structure in shaking table test scale model. Firstly, a method that replaces complex concrete substructures of the suspen-dome prototype structure with steel substructures in
shaking table test scale model was proposed. And then, a dynamic integral scale model considering substructures was established. After that, the natural frequencies of the model were obtained by conducting white noise sweep test. Finally, the numerical scaled model was established by ABAQUS
software, and the numerical model of the prototype structure was established by Midas/Gen software. The natural frequency, mode shape, and seismic response of the scale model were compared with the prototype structure. It is observed that the natural frequencies of the test scale model were
very close to that of the prototype structure after considering the scale ratio, and the scaled model's first five modes were basically consistent with that of the prototype structure. Besides, the difference in acceleration response between the two modes is also small. It is proved that in
shaking table test, the method of designing the integral scale model of replacing complex concrete substructures of the prototype structure with steel substructures is accurate and effective. The analysis results provides a reference for researchers and designers to more conveniently establish
scaled models of suspen-dome structures in shaking table tests.
Vibration Control of Metal Spatial Structures With Tuned Mass Dampers
Authors: Yoshinaka Susumu , Kawaguchi Ken'ichi , Fujiwara Jun , Kishida Akiko , Yamakawa Makoto
Published: July 2023

additional-mass-type vibration-control devices, especially TMDs, and confirm their control performance under seismic loadings by both analytical and experimental methods. Firstly, to effectively control spatial structures that have different vibration properties than multi-story frame
structures, we propose a spatially distributed MTMD method. This method is characterized by controlling plural modes with closely spaced natural frequencies based on the robust property of the MTMD against variation of natural frequencies. Next, we propose a TMD-with-initial-displacement method
to improve transient response. Then, we describe a shaking table test using TMD models and compare test results and analytical results. Lastly, we describe a method of applying a Houde damper system through a real construction project; the Eye of the Yellow Sea Pedestrian Bridge.
The Gridshells for the San Francisco Salesforce Transit Center
Authors: Stutzki Christian , Knowles John
Published: July 2023

The century project TRANSBAY TRANSIT CENTER in San Francisco, designed by the architects Pelli Clark Pelli, has a spacious park on the roof level, with several skylights, for the purpose to funnel daylight into the lower floors of the building. Three of those skylights are grid shells,
each consisting of a filigree grid of steel members, cables, and a double-curved, glazed surface. This paper is about the design, detailing, and construction of these grid shells. These grid shells are not extreme in span or shape; they are of a mature building type, but still innovative for
most designers and engineers. The design is resulting in three structurally robust buildings, consisting of components with many varied materials, from different manufacturers, with different tolerances, brought together successfully through a holistic planning process from the beginning.
Seismic Design of Sports Arena for Tokyo Olympic 2020 Using Energy-Dissipation Devices
Authors: Sugiura Yoshikazu , Nishikawa Daisuke , Hitomi Yasuyoshi
Published: July 2023

This facility was used for the Tokyo 2020 Olympic and Paralympic Games. It is a multi-purpose arena with up to 11,000 seats, and the roof covers the large space of the auditorium and stadium column-free. In this paper, the structural design of the main arena is introduced. The roof
frame is structured by steel pipe trusses with simple planar trusses as a basic unit. Each planar truss is designed in accordance with the bending moment distribution which occurs in the various span each frame has. By arranging these planar trusses with various shapes, a free roof form is
possible to be realized rationally. Oil dampers are installed at the joint of the truss girder and the truss columns, giving the damping effect of earthquake and wind. The dampers are effective at reducing vibrations not only horizontally but also vertically. With respect to unexpected earthquakes,
this design is based on the concept of fail-safe, so as to ensure safety. Based on the idea above, large space structure with higher safety is realized using a simple structural system.
Stability Analysis of Free-Form Reticulated Shells With Semi-Rigid Joints
Authors: San Bingbing , Zhao Wenhui , Qiu Ye , Han Shiwen
Published: July 2023

Focusing on the free-form reticulated shells with semi-rigid joints, a stability study is conducted in this paper. Firstly, the gradient-based optimization and genetic optimization are conducted respectively, by which the local optimal shell and the global shell are obtained. A parametrical
non-linear stability analysis is performed on the local and global optimal reticulated shells using ANSYS. Then, the ultimate bearing capacity and instability modes of both shells are obtained. The semi-rigid joints are modelled by non-linear spring element, named COMBIN39. The effects of
bending stiffness, torsional stiffness, initial geometrical imperfection and load cases are investigated.
The Impact of Human Capital Readiness on Business Performance : The Mediating Role of Innovation Capability
Authors: Linda Sutanto  , Bambang Tjahjadi  , Fiona Niska Dinda Nadia
Published: July 2023

This study investigates the role of innovation capabilities in mediating the link between human capital readiness and business performance. This study's essential contribution is empirically examining the resource-based theory using a structural equation model. This study is a quantitative investigation at the explanatory level that employs structural equation modelling. In Indonesia, 258 owners or managers from MSME’s. The following are the findings: Human capital readiness impacts business performance. Second, innovation capability impact on business performance. Third, innovation capability mediate the relationship between human capital readiness and business performance. This study concludes the strategic roles of innovation capability in Indonesian MSMEs.
Minimalist Sofa Redesign Using the Kano Method
Authors: Yusuffa Depry , Jakaria Ribangun Bamban
Published: July 2023

UKM Mebel Berkah Raya is a company engaged in the field of furniture, one of the products produced is Sofa products. The large number of competitors who are the company's competitors, makes it difficult for the products produced to compete with similar products on the market, therefore, the company conducts a preliminary survey involving loyal customers owned by UKM Mebel Berkah Raya, in order to find out the desires of customers for sofa products, especially sofa products that are produced by the UKM furniture, Berkah Raya. The data obtained shows that the problem that is owned by the product sofa produced by UKM Mebel Berkah Raya lies in the product design attributes, so that with the problems that are owned, further research is carried out which aims to find out in detail the problems that are owned, to then carry out re-design of the sofa product, so that it will produce a sofa product that is in accordance with the customer's wishes. This study uses the Kano method to determine the level of customer satisfaction with a product by paying attention to the attributes attached to the product. so that the level of urgency of each Voice of Customers, so that action can be taken according to the priority level of the results obtained. The results of this study are that the attributes that will be developed with the provisions of Attractive that produce customer satisfaction. attributes Indiffrent that can generate positive feedback with customers.attribute One-Dimantion can increase customer satisfaction. So that the resulting design in the form of an existing sofa design is representative of the measurements that have been carried out with the method used.
Integration of Economic Order Quantity (EOQ) Method and Min-Max Stock Method in Controlling Raw Material Inventory in The Furniture Industry
Authors: Hakiki Gema Fajar , Jakaria Ribangun Bamban
Published: July 2023

Indonesia is a country with a very rapidly developing economy in the manufacturing sector that produces furniture products. The existence of fierce competition between companies and the limited supply of raw materials makes the need for raw materials in the production process uncontrollable so that the desired goals of the company cannot be achieved. One of the factors that greatly influences is regarding the problem of raw material inventory levels. The issue of raw materials is very important for an enterprise because it has a great influence on the profit obtained.Economic Order Quantity (EOQ) and Min-Max Stock methods are carried out to control raw material inventories resulting in savings with optimal purchases by not experiencing inventory shortages.This research is expected so that waste and inventory that are too small can be known at intervals of time to be more effective and efficient in the production process.From the results of analysis and data processing, it can be seen that the number of orders for sonokeling wood raw materials needs is 17.670 m3 and amara wood raw materials are 4.325 m3 with an order frequency of 1 time and an ordering cycle distance of 33 days. So the delay in raw material inventory is influenced by several factors, namely the purchase price of wood raw materials, estimates in using raw materials, purchasing policies from companies and government policies related to regulations with the Multistakeholder Timber Verification and Legality System (SLVK) for inventory control are still lacking.
Afyon Ovası Kuzeybatı Bölümü Yeraltısularının Hidrojeokimyası, İçme ve Sulama Suyu Özelliklerinin Belirlenmesi
Authors: BAŞARAN Can , MANAP Hüseyin
Published: July 2023

Afyon Ovası kuzeybatı bölümünde yer alan yeraltısuları, yaklaşık 8000 kişi tarafından şebeke suyu olarak kullanılmakta ve bölgeden üretilen sularla yaklaşık 56km2 tarımsal alan sulanmaktadır. Su kaynaklarının etkin ve verimli bir şekilde kullanılması için suların fiziksel, kimyasal özelliklerinin ve su kalitelerinin çok iyi bilinmesi gerekmektedir. Bu amaçla, çalışma kapsamında 12 adet yeraltısuyu örneklenerek suların güncel kompozisyonlarını kazandıran hidrojeokimyasal süreçler belirlenmiş, analiz sonuçları içme suyu standardı ile karşılaştırılmış, sulama suyu kaliteleri Elektriksel iletkenlik (EC), Schoeller ve Wilcox Diyagramı, Sodyum Tehlikesi (%Na ve SAR), Kalıntı Sodyum Karbonat (RSC), Magnezyum Oranı (MR), Potansiyel Tuzluluk (PS) ve Kelley indeksi (KI) gibi parametreler kullanılarak yorumlanmıştır. Elde edilen analiz sonuçlarına göre suların majör katyonlarının Ca, Mg ve Na, majör anyonun ise HCO3 olduğu belirlenmiştir. Bölgede yüzeyleyen şistler ve karbonatlı kayaçlar suların güncel bileşimini etkilemektedir. Bununla birlikte bazı su noktalarında tespit edilen ve sınır değeri aşan nitrat, arsenik, flor ve bor gibi elementler evsel-tarımsal atıklardan ve gübrelerden kaynaklanabilir. İncelenen su örneklerinin içilebilirlik ve sulama suyu özellikleri bakımından her türlü kullanımında dikkatli olunması ve gerekli tedbirlerin alınması gerekmektedir.
Günebakan (Erzincan) Seli Örneği ile Esence Dağları’nın Güney-Güneybatı Aklanında Oluşan Moloz Yüklü Eski ve Yeni Selleri Denetleyen Morfometrik Faktörler
Authors: POLAT Pınar , KOPAR İbrahim , YALÇIN Fatih
Published: July 2023

Çalışma alanı Erzincan Ovası’nı kuzeyden, kuzeybatı (KB)-güneydoğu (GD) doğrultusunda sınırlayan Keşiş (Esence) Dağları’nın (Keşiş Tepe, 3549 m) ovaya bakan güney-güneybatı aklanında yer alan, birbirinden subölümü hatları ile ayrılmış, paralel drenajlı çok sayıda akarsu havzasını temsil eden Günebakan Dere, Allahmedet Dere ve Çadırtepe Dere havzalarını kapsamaktadır. Bu çalışmada ilk olarak Günebakan Dere Havzası’nda 17/07/2011, diğeri ise 03/07/2020 tarihinde olmak üzere iki kez afet boyutunda meydana gelen ve önemli mal kayıplarıyla sonuçlanan sel-taşkın olayının oluşum ve gelişim süreciyle doğal ve beşeri çevre üzerindeki etkileri incelenmiştir. İkinci olarak Erzincan Ovası’nı kuzeyden kuşatan Esence Dağları’nın güney-güneybatı aklanında birbirine komşu olan Günebakan, Çadırtepe ve Allahmedet Dere havzalarının morfometrik özellikleri ortaya konularak sel-taşkın üretme potansiyelleri araştırılmıştır. Bu kapsamda Günebakan Dere Havzası’nda oluşan sel-taşkın olayını önceleyen bir yaklaşımla mevcut akarsular üzerinde oluşan/oluşması muhtemel olan sel-taşkın olaylarında havza morfometrisinin etki düzeylerini belirlemek amacıyla alansal, çizgisel ve relief morfometrik indislerden yararlanılmıştır. Çalışma kapsamında yapılan analizlerde havzaların uzunluğu, genişliği, şekli, engebelilik derecesi, drenaj yoğunluğu, akarsu sıklığı ve uzunluğu, akarsuyun çatallanma oranı, yüzeysel akış uzunluğu ve akım toplanma zamanı gibi parametreler değerlendirilmiştir. Analiz sonuçlarına göre havzaların morfometrik yapısıyla moloz akmaları arasında yakın bir ilişki olduğu belirlenmiştir. Elde edilen sonuçlara göre aynı aklandaki Günebakan Dere Havzası’nın gerek yatak eğimi ve genişliği, gerekse çatallanma oranı ve uzunluk değerleri gibi parametreler ölçeğinde komşu havzalara göre sel ve taşkın üretme potansiyeli daha yüksek olan havza olduğu sonucuna ulaşılmıştır.
QGIS-Qproto yazılımı ile Konik Temelli 3 Boyutlu Kaya Düşme Modellemesi: Mazı Köyü Örneği-Nevşehir (Ürgüp)
Authors: UTLU Mustafa , AKGÜMÜŞ Mehmet Fatih
Published: July 2023

Bu çalışma, kaya düşme olaylarının yoğun olarak meydana geldiği Nevşehir ili’nde Derinkuyu ve Ürgüp ilçelerine yakın Mazı Köyü kuzeyinde ve Güneyce Köyü yolu’na 1,34 km mesafede bulunan sahanın yüksek çözünürlükte İHA-SAM verisi kullanılarak bir QGIS eklentisi olan Qproto kullanarak üç boyutlu (3B) konik temelli kaya düşme modellemesini kapsamaktadır. Çalışma sahasında kaynak zonlara karşılık gelen volkanik kökenli ignimbiritler, özellikle kornişlere karşılık gelen yüksek eğimli dik bir yamaç profiline sahiptir. Bu bakımdan, düşeye yakın süreksizliklerin oluştuğu ignimbiritlerde yoğun olarak görülen soğuma çatlaklarına (düşey süreksizlikler) sahip yapıdaki kaya kütlesi içerisinde 16 adet düşme ihtimali olan kaya bloğu tespit edilmiş, bunlara ait kaya düşme modellemesi gerçekleştirilmiştir. Modelleme sonuçlarına göre, maksimum 142 kJ kinetik enerji ve 16.8 m/s ötelenme hızına sahip kaya düşmeleri belirlenmiştir. Bu sonuçlara göre, saha sınırları içerisinde yer alan düşme modelinin maksimum değerlere, genel olarak yüksek eğim değerlerinin olduğu alanlarda ulaşılmış olup, mevcut gravitasyonel durumun, özellikle eğimin azaldığı noktalarda kaya bloklarının enerjilerinin ve hızlarının sönümlendiği gözlemlenmiştir. 5 sınıfta kaya düşme duyarlılık derecesi oluşturulmuş, özellikle kaya düşmeleri sonucunda düşen blokların saçıldığı ve yayılış gösterdiği yörüngelerin daha çok orta- yüksek ve çok yüksek duyarlılıkta sınıflara karşılık geldiği gözlemlenmiştir.
Keşif Kuraklık İndeksi ve Standartlaştırılmış Yağış İndeksi Kullanılarak Kırklareli İlinde Kuraklığın Eğilimi ve Zamansal Değişkenliği
Authors: YILMAZ Mustafa Utku
Published: July 2023

Bu çalışma, ekonomisi büyük ölçüde tarıma dayalı olan Kırklareli ili için kapsamlı bir kuraklık analizi sunmayı amaçlamıştır. Kuraklığın eğilimi ve zamansal değişkenliği, Standartlaştırılmış Yağış İndeksi (SYİ) ve Keşif Kuraklık İndeksi (KKİ) kullanılarak 1, 3, 6, 9 ve 12 aylık zaman ölçeklerinde incelenmiştir. SYİ ve KKİ’yi hesaplamak için Kırklareli meteoroloji istasyonunun 1960-2021 su yılları arasındaki aylık yağış ve sıcaklık verileri kullanılmıştır. Farklı zaman ölçekleri için SYİ ve KKİ serilerinin eğilimlerini belirlemek için Mann-Kendall ve modifiye Mann-Kendall testleri, serilerdeki eğilimlerin büyüklüğünü belirlemek için Sen’in eğimi ve serilerin değişim noktasını tespit etmek için Pettitt testi kullanılmıştır. Sonuçlar, SYİ ve KKİ'nin tüm zaman ölçekleri için benzer şekilde davrandığını ve her iki indeksin de neredeyse aynı kuraklık olaylarını yakalayabildiğini ortaya koymuştur. Bununla birlikte, SYİ'nin aynı zaman ölçeğindeki KKİ ile güçlü bir doğrusal ilişkiye sahip olduğu gözlenmiştir (r=0.99). KKİ’nin çoğunlukla SYİ'den biraz daha yüksek değerlere sahip olduğu ve şiddetli ve aşırı kuraklık olaylarının tespitinde daha hassas olduğu sonucuna varılmıştır. Farklı zaman ölçeklerinde kuraklık olaylarının oluşum yüzdeleri, SYİ’ler için %46.9 ile %51.3 arasında ve KKİ’ler için %47.2 ile %50.6 arasında değişmiştir. Her iki indeks için 12 aylık zaman ölçeğinde, 1989 yılı Şubat ayı ile 1995 yılı Mayıs ayı arasındaki 76 ay hem en uzun hem de en şiddetli kurak dönem olarak belirlenmiştir. Zaman ölçeği arttıkça kuraklık olaylarının sayısı azalmış ve kuraklık süresi artmıştır. Tüm zaman ölçeklerinde SYİ ve KKİ değerleri için istatistiksel olarak anlamlı bir eğilim bulunmamıştır (p>0.05). Her iki indeks için de 1 aylık zaman ölçeğinde değişim noktası bulunmazken, 3, 6, 9 ve 12 aylık zaman ölçeklerinde değişim noktası tespit edilmiştir.
Investigation of In Vitro antiproliferative activity properties of Spartium junceum L. (Spanish broom) against MDA-MB-231 and HepG2 cancer cell lines
Authors: GÜRAĞAÇ DERELİ Fatma Tuğçe , AKKOÇ Senem
Published: July 2023

Cancer is among the top global public health burdens leading to millions of deaths each year. The study aims to investigate the antiproliferative effect of Spartium junceum L. flowers on different cancer cell lines. The ethanolic extract of the flowers was prepared in the present study. Phytochemical analysis of the plant extract revealed the presence of several phenolic compounds such as cinnamic acid and its derivatives (chlorogenic, p-coumaric, ferulic acids), protocatechuic acid, epicatechin and luteolin. This extract was tested against human breast (MDA-MB-231) and liver (HepG2) cancer cell lines to find out its antiproliferative activity. It was determined that the extract was effective against both cell lines with IC50 values of 2.37 ± 0.47 and 0.98 ± 0.01 µL/mL for MDA-MB-231 and HepG2, respectively. Particularly, the extract was found to be more effective in the liver cancer cell line than the breast cancer cell line. All these obtained findings led us to believe that this medicinal plant could be a promising antiproliferative agent candidate for the treatment of human liver and breast cancers.
In-vitro anti-diabetic, anti-Alzheimer, anti-tyrosinase, antioxidant activities of selected coumarin and dihydroisocoumarin derivatives
Authors: ŞAHİN Hasan
Published: July 2023

Benzo-α-pyrone structured coumarin derivatives are secondary metabolites first obtained from Coumarouna odorata in 1822. Coumarin and its structural isomer dihydroisocoumarin derivatives are found in many different sources in nature. Several different bioactivities of these compounds have been reported. In this study, preliminary activity screening and comparison of four purchased coumarin derivatives (esculetin, esculin monohydrate, umbelliferon, scoparone) and four previously isolated 3-phenyl-3,4-dihydroisocoumarin derivatives (thunberginol C, scorzocreticoside I, scorzocreticoside II, scorzopygmaecoside) from a medicinal plant were carried out by in-vitro methods. α-Glucosidase, acetylcholinesterase, butyrylcholinesterase, tyrosinase inhibitor activities and antioxidant potentials of the compounds were evaluated. Consequently, thunberginol C (free – not glycosylated form of 3,4-dihydroisocoumarin structure) showed better potential in all enzyme inhibitory activities compared to coumarin structure. Particularly, α-glucosidase inhibitory activity of this compound with a very low IC50 value (94.76±2.98 µM) compared to standard acarbose (1036.2±2.70 µM) should be noted. Glycosylation and/or methoxy substitution of 3,4-dihydroisocoumarin structure resulted a significant decrease in all tested enzyme inhibitory activities. The structures of esculin MH, umbelliferone, scoparone, scorzocreticoside I, and scorzopygmaeceoside might be considered in further synthetic studies as selective acetylcholinesterase inhibitors. Thunberginol C has a promising potential in tyrosinase inhibitory activity. Esculetin and thunberginol C showed the best results with high potentials in antioxidant activity via 2,2-diphenyl-1-picryl-hydrazyl-hydrate free radical scavenging, 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid cation radical decolorization, and cupric ion reducing antioxidant capacity assays compared to the standards.
Effects of Grayanotoxin-III on different cell lines: in vitro ischemia model
Authors: AKBAY ÇETİN Esin , ÖZENİRLER Çiğdem
Published: July 2023

Grayanotoxins (GTXs) are natural products and are mostly found in plants of the Ericaceae family, especially in the Rhododendron. With their ability to bind to voltage-gated sodium channels, they keep these channels constantly active and cause tissue damage. However, despite this feature, the use of Rhododendron leaves or its secondary products as an alternative product is especially common in Turkey. This study aims to evaluate the possible dose-related effects of GTX-III in ischemia-induced in vitro cell models. Within the scope of the study, an ischemia model was established in two different cell lines (H9c2 and Cos-7) and treated with various concentrations of GTX-III. In this context, cell viability, cytotoxicity, apoptosis and necrosis were examined. In the results of MTT, a significant decrease (+p < 0.05) in cell viability was observed in all GTX-III concentrations in H9c2 cells compared to the control, while a significant difference (+p < 0.05) was observed in Cos-7 cells, especially at the 24th hour. LDH cytotoxicity was increased in a dose-dependent manner in both cell models. It was concluded that GTX-III caused apoptosis, and reduced cell viability in ischemia models; however, promoted cell proliferation in healthy cells. Based on the literature review, this study is the first to document the cytotoxic properties and apoptotic potential of GTX-III in an in vitro cell culture ischemia model. Our findings support the usage of GTX-III, however it should be remembered that the dose needs to be verified before being used medically.
Mineralogy of the unified soil classes of Wadi As Suqah: A sustainable engineering geology approach
Authors: Alotabi Musaad A. , Alghamdi Mohammed A. M.
Published: July 2023

This research endeavors to enhance soil classification methodologies in alignment with sustainability goals for mining and construction activities. The study focuses on the evaluation, classification, and mapping of quaternary surface deposits in Wadi As Suqah. To achieve this objective, an integration of mineral analyses and unified soil classes was employed. Various research methods were utilized, including Geographic Information Systems (GIS), sieve analysis, Atterberg limits, and X-ray diffraction. Additionally, principal component analysis (PCA) on variance was employed to identify the most influential minerals within the deposits. Consequently, a sophisticated engineering geological map of the deposited category was created, resulting in the categorization of Wadi As Suqah into 13 groups (A, B, C, …, L) based on similar lithofacies. These groups further represented 7 clusters of mineral-based classes, such as quartz-anorthite or quartz-albite, leading to the formation of 5 unified soil classes, namely SP, SP-SM, SM, SC-SM, and SC. Among the classified groups, group C, characterized by rich sandy quartz with some albite content, emerged as the largest group, occupying 20.3% of the total area. Conversely, group M, consisting of rich fine anorthite with a trace of quartz, constituted the minor group, representing only 0.5% of the entire area. The study acknowledges the limitations of being confined to surface investigations and, therefore, strongly recommends further subsurface investigations for a more comprehensive geotechnical understanding. The findings of this research hold significant implications for sustainable mining and construction practices by enabling a refined soil classification approach based on mineral composition and unified soil classes.
Exploration of Digital Media Integration and Development Path under Internet + Environment
Authors: Tang Haoqi
Published: July 2023

With the continuous popularization of the Internet and the ongoing development of digital technology, the application of digital media in the environmental field is becoming increasingly widespread. This article explores the development path of digital media integration in the Internet Plus environment and proposes future trends and challenges for digital media in the environmental field. Through research and analysis, this article believes that the development of digital media integration in the environmental field should focus on the following aspects: strengthening technological research and development to enhance the application level of digital media in environmental monitoring, early warning, and governance; strengthening information construction to enhance the role of digital media in environmental information sharing, dissemination, and communication; strengthening talent training to cultivate interdisciplinary talents with backgrounds in environmental science and digital technology, and promote innovation and application of digital media in the environmental field. This article aims to provide references and insights for the development of digital media in the environmental field, promote the deep integration of digital media and environmental science, and make greater contributions to the cause of environmental protection.
The Evaluation of Land Use Evolution and Ecological Sensitivity of Guangzhou Based on GIS and RS
Authors: Lin Tong , Wang Ruei-Yuan
Published: July 2023

The dynamic stability of the local ecological environment is related to changes in land use patterns and ecological sensitivity. The study aims to identify the land use characteristics and dynamic change features in Guangzhou City using RS and GIS technology. We choose six ecological sensitivity factors, such as land use type, elevation, watershed buffer, vegetation cover, slope, and slope direction, and use the analytical hierarchy process (AHP) to obtain the results of single-factor and comprehensive ecological sensitivity. The findings indicate that, in terms of land use, the area of four types—forest land, grassland, arable land, and unused land—decreased from 2000 to 2020, while the area of water bodies and construction land rose, with a minimal overall change. According to total ecological sensitivity, very sensitive areas make up the majority of the total area and are primarily found along the northern township boundary; very low-sensitive and mildly sensitive areas are mostly found in the south and center. In order to encourage the development of an ecological civilization in the city, Guangzhou City must establish the idea of harmony between people and the land and increase the ecological conservation function.
A Thermal Insulation and UV-Resistant System based on Aerogel for Settlements on the Moon and Mars
Authors: Veer Kautilya , Mohite Akshat
Published: July 2023

Abstract: This paper presents a novel design for a habitable outpost on both the Moon and Mars that leverages the exceptional properties of aerogel - a material composed of 99% air, offering outstanding thermal insulation and UV protection. The outpost is engineered to withstand extreme temperature variations on Mars (-153°C to 20°C) and the Moon (-173°C to 127°C) using a single material. Protection against harmful UV rays is crucial for sustaining human life as prolonged exposure can lead to DNA damage and cancer. To safeguard the aerogel layer from meteoroids, Martian soil is utilized on Mars, and lunar soil on the Moon. The interior features a fiber composite layer, supported by a mechanical structure made from Martian concrete (ice, calcium oxide, and Martian aggregate) or lunar concrete (ice, calcium oxide, and lunar aggregate). The composite can be assembled on Earth with an inflatable system or sent to Mars in multiple missions for on-site assembly. Light transmission with radiation resistance is achieved using translucent silica aerogel filters for glass windows. The paper also includes heat transfer calculations between the internal and external environments of the habitat, as well as strength assessments of the habitat, taking into account the insulation and UV resistance provided by the protective soil layer.
Covid-19 Pandemisi Sürecinde Birinci Basamak Sağlık Çalışanlarının Kişilik Özellikleri ve Stres Düzeyleri Arasındaki İlişki
Authors: SALBUR Tuğçe , ALTINEL Büşra
Published: July 2023

Amaç: Bu çalışma Covid-19 pandemi sürecinde birinci basamak sağlık çalışanlarının kişilik özellikleri ile stres düzeyleri arasındaki ilişkiyi incelemek amacıyla yapılmıştır.
Materyal-Metot: Tanımlayıcı ilişki arayıcı tipteki bu araştırma Haziran 2021-Eylül 2021 tarihleri arasında, Konya il ve ilçelerinde çalışan 256 birinci basamak sağlık çalışanı ile yürütülmüştür. Veriler “Tanıtıcı Bilgi Formu”, “Algılanan Stres Ölçeği” ve “Büyük Beş Kişilik Testi-50” ile online ortamda toplanmıştır. Veriler sayı, yüzde, ortalama, t testi, ANOVA ve pearson korelasyon testi ile değerlendirilmiştir.
Bulgular: Bu çalışmada sağlık çalışanlarının Büyük Beş Kişilik Testi-50 Dışa Dönüklük alt boyutu puan ortalaması 32,93±7,13; Uyumluluk-Yumuşak Başlılık alt boyutu puan ortalaması 39,77±4,51; Sorumluluk-Özdenetim alt boyutu puan ortalaması 41,35±5,45; Duygusal Dengelilik alt boyut puan ortalaması 30,33±7,51 ve Zeka/Hayal Gücü alt boyut puan ortalaması 39,00±4,66, Algılanan Stres Ölçeği puan ortalaması ise 27,97±6,95 olarak bulunmuştur. Çalışmaya katılan birinci basamak sağlık çalışanlarının cinsiyeti, eğitim durumu ve Covid-19 pozitif hastayla teması ile Algılanan Stres Ölçeği puan ortalaması arasında istatistiksel açıdan anlamlı bir fark bulunmuştur (p<0,05). Algılanan Stres Ölçeği puan ortalaması ile Büyük Beş Kişilik Testi-50 alt boyutlarından Uyumluluk-Yumuşak Başlılık alt boyut puan ortalaması ile negatif yönde zayıf düzeyde ve Duygusal Dengelilik alt boyut puan ortalaması ile negatif yönde orta düzeyde bir ilişki olduğu belirlenmiştir (p<0,001).
Sonuçlar: Sağlık çalışanlarının desteklenmesinin, motive edici aktivitelerin ve stresle baş etme eğitimlerinin düzenlenmesi pandemi gibi süreçlerde faydalı olacağı düşünülmektedir.
Do Estatuto da Criança e do Adolescente ao regimento escolar
Authors: Real Giselle Cristina Martins , Chaves Fernanda Severino
Published: July 2023

Objetiva-se identificar, no Regimento Escolar, os nexos com a construção do direito educacional, previsto no Estatuto da Criança e do Adolescente (ECA). Para tanto, adotou-se como metodologia a análise documental, que teve como corpus o ECA e o Regimento de uma escola da rede estadual de Mato Grosso do Sul. Foi possível inferir que a escola imprime, na norma institucional, as concepções emanadas do ECA, apresentando avanços na direção de apreensão da concepção do direito à educação como um princípio de desenvolvimento integral do cidadão. Por outro lado, observa-se que os profissionais da educação, a partir das definições do Regimento Escolar, são responsabilizados pelo desenvolvimento das ações, bem como das articulações com outros órgãos para o acompanhamento da aplicação das sanções previstas, o que pode representar uma sobrecarga para esses profissionais.