bluuebunny/crossref_metadata_2025 huggingface dataset:
Association between TPH1 polymorphisms and the risk of suicide behavior: An updated meta-analysis of 18,398 individuals
Authors: Genis-Mendoza Alma Delia , Hernández-Díaz Yazmín , González-Castro Thelma Beatriz , Tovilla-Zárate Carlos Alfonso , Castillo-Avila Rosa Giannina , López-Narváez María Lilia , Ramos-Méndez Miguel Ángel , Nicolini Humberto
Published: July 2022

Objectives

We aimed to examine the association ofTPH1polymorphisms with the risk of suicide behavior (SB).

Design

Systematic review and meta-analysis.

Method

All relevant studies that evaluated the association between the A218C (rs1800532), A779C (rs1799913) and A6526G (rs4537731) polymorphisms and the susceptibility to SB published up to September 2021 were identified through a comprehensive systematic search in PubMed, Scopus, EBSCO and Science Direct electronic databases. The association betweenTPH1gene polymorphisms and SB was evaluated using inherence models by odds ratio (OR) and 95% confidence interval (CI). Subgroup analyses, heterogeneity analyses, and publication bias were also tested in this meta-analysis.

Results

The meta-analysis forTPH1A218C revealed an increased risk of SB in the dominant model (OR = 1.11, 95%CI 1.01–1.22). We also observed a positive association in the allelic (OR = 1.13, 95%CI 1.05–1.21), homozygous (OR = 1.22, 95%CI 1.06–1.40), heterozygous (OR = 1.21, 95%CI 1.08–1.37) and dominant (OR = 1.21, 95%CI 1.09–1.34) inherence models with the suicide attempt. Additionally, in the heterozygous (OR = 0.84, 95%CI 0.73–0.97) and dominant (OR = 0.79, 95%CI 0.68–0.91) inherence models we detected an association with completed suicide. Based on ethnicity, an association of SB in the European population also was observed (OR = 1.29, 95%CI 1.12–1.51). However, for both A779C and A6526G polymorphisms we did not find evidence of an association with SB.

Conclusion

This meta-analysis suggests that the A218C polymorphism ofTPH1gene could be a possible risk factor of SB. Future large-scale studies are required to analyze the molecular mechanisms by which affect the susceptibility of developing suicide behavior.
Mental health in individuals with self-reported psychiatric symptoms during the COVID-19 pandemic: Baseline data from a swedish longitudinal cohort study
Authors: Rozental Alexander , Sörman Karolina , Ojala Olivia , Jangard Simon , El Alaoui Samir , Månsson Kristoffer N. T. , Shahnavaz Shervin , Lundin Johan , Forsström David , Hedman-Lagerlöf Maria , Lundgren Tobias , Jayaram-Lindström Nitya
Published: July 2022

Objective

Individuals with psychiatric disorders may be both vulnerable and sensitive to rapid societal changes that have occurred during the COVID-19 pandemic. To fully understand these impacts, repeated measurements of these individuals are warranted. The current longitudinal study set out to perform monthly assessment of individuals with common psychiatric disorders using established questionnaires with a possibility for them to self- rate their symptoms, over time.

Methods

Recruitment of individuals who identified themselves as struggling with mental health problems, living in Sweden between July 2020 and June 2021 using an online survey. The individuals answered questions on demographics, psychiatric history, current psychiatric symptoms (e.g., Patient Health Questionnaire, PHQ-9; General Anxiety Disorder, GAD-7), somatic health, health-care contacts and any changes therein during the pandemic. Monthly, longitudinal assessments are still ongoing (consenting participants provide data for 1 year), and here we present descriptive statistics from the baseline measurement. All measurements from baseline (>400 items), and follow-ups are presented in detail.

Results

A total of 6.095 participants (average age 35 years) submitted complete baseline data. Marital status (43% single) and number of years of education (48% highest degree being high school) were evenly distributed in this population. The most common lifetime psychiatric disorder in the sample was depressive disorder (80.5%) and generalized anxiety disorder (45.9%), with a substantial proportion having severe symptoms of depression. (30.5%) and anxiety (37.1%). Lifetime suicidal ideation (75.0%) and non-suicidal self-harm (57.7%) were prevalent in the group and 14.5% reported drug use during the pandemic. Allergies (36.8%) were the most common somatic condition, followed by irritable bowel syndrome (18.7%). For those having experienced a traumatic event, 39% showed symptoms during the pandemic indicating PTSD. Regarding contact with mental health services during the pandemic, 22% had established a new contact, and 20% reported to have increased their psychiatric medication compared to before the pandemic.

Conclusion

Baseline data collected during the pandemic from individuals in Sweden with pre-existing psychiatric disorders demonstrate that this sample represents a population suitable for an investigation on the long-term impact of the pandemic, as intended by the longitudinal investigation that is ongoing. Follow-up questionnaires over a 12-month period are being collected and will indicate how the health and well-being of this population was impacted during the changes and uncertainties that have been characteristic of the past 2 years.
Communication Mechanisms and Implications of the COVID-19 Risk Event in Chinese Online Communities
Authors: Pengpeng Li , Fangqi Zhong , Qianru Zhuo
Published: July 2022

Based on the context of communication and use of online communities in China, this study explored the characteristics and defects of risk communication of the government and official media in the event of COVID-19, as well as the factors that affected people's perception of the risk and protective behavior. The following results were found: (1) The government and official (mainstream) media accounts suffered from information lag in the early stage of COVID-19, while self-media accounts played the role of risk sensors, which caused people to have less trust in the government and the authorities and turn to the truth on self-media accounts. However, the low accessibility of self-media accounts and the imperfect check mechanism provided a hotbed for rumors, which further led to more fear and worry about risks. (2) During the middle and later periods of COVID-19, the government and the official media began to pay attention to the influence of self-media on peoples' emotions and behavior, and gradually improved the supervision of online information and the operation of official media accounts. This is intended to achieve information consistently and link mechanisms between official media and self-media to prevent and correct mistakes, as well as to achieve effective risk communication of information transparency, opinion exchange, and public sentiment stabilization.
Self-reported side effects of the Oxford AstraZeneca COVID-19 vaccine among healthcare workers in Ethiopia, Africa: A cross-sectional study
Authors: Yesuf Elias Ali , Riad Abanoub , Sofi-Mahmudi Ahmad , Sudhakar Morankar , Mekonnen Addisalem , Endalkachew Selamawit , Mama Feyissa , Muhidin Semira , Ayele Bethelhem , Yahya Mohammed , Usman Abduselam , Abafita Jemal , Klugar Miloslav
Published: July 2022

Introduction

Ethiopia is the second most populous country in Africa. Ethiopia received most of its COVID-19 vaccines through donations. The Oxford AstraZeneca vaccine is the first to be donated to Ethiopia by the COVAX facility. Healthcare workers were the priority population that received the Oxford AstraZeneca COVID-19 vaccine. However, there was no nationwide study on the safety of the vaccine in Ethiopia. This study aimed to measure the prevalence and predictors of self-reported side effects of the Oxford AstraZeneca vaccine.

Materials and methods

The study employed a cross-sectional design. A sample of healthcare workers who took Oxford AstraZeneca COVID-19 vaccine was drawn from four regions of Ethiopia; namely, Amhara, Oromia, Somali, and Southwest. Data were collected on sociodemographic characteristics, medical anamnesis, COVID-19 related anamnesis, and COVID-19 vaccine anamnesis via telephone interview. Descriptive and inferential analyses were done. The software, IBM SPSS Statistics v21.0, was used for analyses of data.

Results

Out of 384 people, 346 responded (response rate: 90.1%). Female accounted for 34.1% of the respondents. The mean age of the respondents was 31.0 years (Standard Deviation (SD) = 7.4). Nurses accounted for 43.7% of the respondents. The prevalence of at least one local- and systemic-side effect was 50.6 and 44.5%, respectively. The most frequent local- and systemic- side effect were injection site pain and headache, respectively. Both types of side effects mostly subsided in the first 3 days. A third of healthcare workers with side effects took at least one medication. Paracetamol followed by diclofenac sodium were taken by healthcare workers to overcome side effects. There was no independent predictor of local side effect. After controlling for age and chronic diseases, the odds of healthcare workers with COVID-19 like symptoms to experience systemic side effects was 1.38 (Confidence Interval (CI): 1.04–1.82) times more than that of healthcare workers without COVID-19 like symptoms.

Conclusions

The prevalence of local- and systemic-side effects of the Oxford AstraZeneca COVID-19 vaccine was modest. As the symptoms were mostly common in the first 3 days, it is preferable to monitor healthcare workers at least in the first 3 days following the administration of the vaccine.
Spittlebugs (Hemiptera: Cercopidae): Integrated Pest Management on Gramineous Crops in the Neotropical Ecozone
Authors: Espitia Buitrago Paula Andrea , Manzano Maria R. , Hernández Luis M.
Published: July 2022

Spittlebug (Hemiptera: Cercopidae) species cause large economic losses on gramineous crops (Poaceae) in tropical and subtropical America. These insects are key pests of sugarcane and forages, crops that experienced a quick expansion in extensive monocultures in Brazil, Colombia, and Mexico. Mobilization toward sustainable crop and livestock systems to supply the growing demand of meat, milk, and sugar in Latin America and the Caribbean region implies developing sustainable and feasible strategies of integrated pest management to control spittlebugs. This review combines information on Cercopidae taxonomy, geographical distribution, insect biology, and control strategies to contribute to the development of integrated pest management in grasses and sugarcane in the Neotropics.
Use of Cytopoint in the Allergic Dog
Authors: Gober Margaret , Hillier Andrew , Vasquez-Hidalgo Manuel A. , Amodie Deborah , Mellencamp Martha A.
Published: July 2022

Allergic dermatitis is the most common type of skin disease in dogs. Of all dogs, 20 to 30% present with some type of allergic dermatitis. Pruritus is one of the most important signs of allergic dermatitis and is often the most challenging to control. Interleukin-31 (IL-31) has been found to be one of the main initiators of pruritus in dogs with allergic dermatitis. Cytopoint®, a caninized monoclonal anti-IL-31 antibody, has been shown to be effective for the treatment of dogs against allergic dermatitis and atopic dermatitis. US label indication. A recent retrospective study reported that Cytopoint achieved treatment success in 87.8% of the cases with allergic dermatitis. No prospective cohort studies have been performed investigating the effects of Cytopoint in dogs with allergic dermatitis using the dosing protocol prescribed on the product label in the United States. In this study, our objectives were to assess the efficacy of Cytopoint for treatment of canine allergic dermatitis of variable etiologies and management of the associated pruritus, and add to the body of evidence available to the veterinarian as they make treatment recommendations. Dogs included in this study had moderate to severe pruritus according to the Pruritus Visual Analog Scale (PVAS; ≥ 50 mm) and a history of likely continuation of pruritus at the time of presentation. On day 0, investigators recorded the initial body weight and every patient received one dose of Cytopoint (minimum 2 mg/kg SQ) and an isoxazoline product for parasite control. Treatment success for this study was defined as a ≥20 mm reduction in PVAS from Day 0. On Day 7, 94% of the dogs had achieved treatment success. On Day 28, 98% had achieved treatment success and cumulatively by day 56, 100% of the dogs achieved treatment success. This prospective study provides evidence that Cytopoint effectively treats dogs with allergic dermatitis of different types and the associated pruritus.
Steroid-Based Liquid Crystalline Polymers: Responsive and Biocompatible Materials of the Future
Authors: Czubak Bartlomiej , Warren Nicholas J. , Nagaraj Mamatha
Published: July 2022

Steroid-based liquid crystal polymers and co-polymers have come a long way, with new and significant advances being made every year. This paper reviews some of the recent key developments in steroid-based liquid crystal polymers and co-polymers. It covers the structure–property relationship between cholesterol and sterol-based compounds and their corresponding polymers, and the influence of chemical structure and synthesis conditions on the liquid crystalline behaviour. An overview of the nature of self-assembly of these materials in solvents and through polymerisation is given. The role of liquid crystalline properties in the applications of these materials, in the creation of nano-objects, drug delivery and biomedicine and photonic and electronic devices, is discussed.
Transarterial Treatment of Lung Cancer
Authors: Hori Atsushi , Dejima Ikuo , Hori Shinichi , Oka Shuto , Nakamura Tatsuya , Ueda Shota
Published: July 2022

Purpose: The treatment efficacy of the transarterial approach to lung cancer is evaluated. Materials and Methods: A total of 98 patients with advanced lung cancer or recurrent lung cancer after the standard therapies were enrolled retrospectively. The bronchial arteries and mediastinal branches from the subclavian artery were selected by a microcatheter. Immediately after the selective arterial infusion of anti-neoplastic agents, embolization with a spherical embolic material was carried out. Local tumor effects and overall survival were evaluated. Result: The mean reduction rate was 17.9%, with 24.2% for partial remission and with 2.1% for progression disease. The rate of stable disease was 72.6%. The response rate was 25.3%, and the disease control rate was 97.9%. The median survival time (MST) was 11.4 months, the 1-year survival rate was 45.2%, and the 2-year survival rate was 35.6%. Although it is insignificant, the MST for 51 adenocarcinomas was higher than that of 29 squamous cell carcinomas (18.6 months and 9.4 months, respectively). The local extension of tumors related to a better prognosis, though it was not significant. Lymph node metastases and distant metastases were poor prognostic factors. No major complications nor treatment-related mortalities were found in this study. Conclusion: The transarterial treatment for lung cancer should be considered as a treatment option when the other treatments were not indicated both in initial cases and in recurrent cases.
Value of Mineralogical Monitoring for the Mining and Minerals Industry
Authors: König Uwe , Pöllmann Herbert
Published: July 2022

The shift towards lower grade ore deposits, sustainable energy, CO2 reduction, volatile market conditions and digitalization has pushed the mining and minerals industry towards predictive, sustainable and agile analytical solutions to improve safety and increase operational efficiency [...]
Attitudes toward Immigrants Intertwined with Religion: Comparison of Croatia and Italy
Authors: Stipišić Teuta
Published: July 2022

This article seeks to contribute to the study of migration and religion in two EU countries, Croatia and Italy, by examining the impact of religiosity and cultural identification on negative attitudes toward immigrants. In many European societies, the increasing diversification within different levels of society stemming from recent migrations has turned immigrants’ reception and integration into a key issue, whereby migrants are often perceived as a threat to the dominant religion and culture, thus aggravating the process of migrant integration within society. Our article follows recent empirical research on migration and religion, which determined that higher levels of religiosity are positively correlated with negative out-group attitudes. Conducting quantitative research in Croatia (N = 603) and Italy (N = 714) and based on the analysis of primary data, firstly, we assess whether there is an association between negative attitudes towards immigrants depending on different degrees of religiosity and levels of cultural identification. Secondly, we examine the differences of the socio-religious contexts of Croatia and Italy, with a focus on the interplay between religion, national identity, and migration patterns. In line with this, our research shows that religiosity has the largest influence on negative attitudes toward immigrants, implying that higher levels of religiosity result in higher levels of negative attitudes toward immigrants. Furthermore, the results of our research show that Croatian participants have more negative attitudes toward immigrants than Italian participants, whereby Roman Catholic participants in both countries are more negative than non-religiously declared participants.
Theoretical and experimental investigations for noise reduction of clearance joints in vertical vibrations
Authors: Sadri Milad , Forouzan Mohammad Reza
Published: July 2022

Simple revolving clearance pin and bush joint is standard and is widely used in machines and mechanisms. Clearance is necessary for rotational mobility of the joint parts, but it may lead to contact loss, which produces noise. To avoid the contact loss, it is necessary to ensure equality
between the accelerations of the driver and the driven parts of the joint. In the case of a driver pin inside a bush as a free-driven part of the clearance joint, the acceleration of the bush in the vertical direction is limited to gravity. Therefore, if the exciting pin vibrates with downward
acceleration more than the gravity, the contact loss will occur. As a solution, the acceleration of the free part was increased by a symmetric set of springs and a wire. To predict the contact condition, a set of dynamic equilibrium equations was developed and used to obtain the minimum spring
stiffness and preload. Simulation and experimental results verified the concept of the contact loss and proved the effectiveness of using proper spring on noise reduction. Theoretical results show that with a sufficient spring preload, it is possible to use an arbitrary stiffness down to a
limit even at relatively large accelerations. According to the acoustic tests, the noise picks were attenuated considerably, and the noise level was reduced to the background noise level after using proper springs.
Case study: Analysis of acoustic-structure coupling noise characteristics of the exhaust muffler of an internal combustion engine
Authors: Hou Zhenhua , Si Tengfei , Zhang Shiqiang , Zhang Zhijun , Sun Jiyu
Published: July 2022

Exhaust noise produced by internal combustion engines is one of the main problems of vehicle noise, and exhaust mufflers can significantly improve this problem. In fact, the sound waves inside the exhaust muffler will cause the muffler shell to vibrate, causing the muffler to produce
shell radiation noise. Therefore, it is necessary to carry out the acoustic-structure coupling analysis of the muffler. This paper improved the design of a prototype straight-through perforated pipe-resistant muffler (design A) and designed a straight-through perforated pipe-resistant muffler
with a corrugated lining (design B). Structural modal analysis, acoustic modal analysis, and transmission loss analysis of the two mufflers were carried out. The coupling of the acoustic cavity and structure was considered, and the radiation noise of two kinds of resistant mufflers was comparatively
analyzed by the direct-boundary-element method. The acoustic radiation of two kinds of resistant mufflers was studied. The pressure loss of the two kinds of mufflers was studied by aerodynamic analysis. The results suggested that the design B muffler effectively improved the noise reduction
performance of the prototype muffler, reduced the vibration displacement amplitude of the shell, and reduced the sound power level of the design A muffler.
Efficient simulations for the democratization of duct transmission loss analysis
Authors: Hamiche Karim , Marvi Aamir
Published: July 2022

As in many industries, NVH reduction in the automotive market requires car manufacturers to adapt their designs and development methods. In particular duct system design necessitates accurate methods to capture the resonance frequencies and address noise phenomena. To do so, engineers
evaluate the quality of the components through numerical simulations and validate against real-life measurements. Two main challenges arise: the simulations are often ran by non-numerical experts, who might have difficulties with setting up the models. Secondly, the computation techniques,
together with the model preparation, need to be efficient to improve productivity. In this paper, an automated workflow is presented to democratize numerical techniques in duct design and sound transmission loss computation. It gives the possibility for non-experts to easily set up and solve
their models with few input parameters. Furthermore, effective numerical techniques based on high-order shape functions with a-priori error estimator are used to optimize performance and accuracy: FEMAO and BEMAO (Finite/Boundary Element Methods with Adaptive Order). Two models are exposed:
a simple duct line with three Helmholtz resonators, and a more complex intake system. The numerical results of the different methods are compared, as well as measurements.
Cryptocurrency mining noise: The cost of progress?
Authors: Thalheimer Erich
Published: July 2022

Love it or loathe it, Bitcoin and other cryptocurrencies are here to stay. Yet do you know how crypto is "manufactured"? It turns out to be a very noisy operation! Hundreds, if not thousands of powerful computer servers and processors are needed to solve the vexing Bitcoin
mining algorithms. And those computers generate heat, a lot of heat (!), that must be cooled and ventilated, thus creating noise. This paper will describe the noise assessment and control efforts performed on a major Bitcoin mining operation in Tennessee. Megawatts of power are needed to support
the operations, and the ventilation noise was causing significant community complaints that threatened to shut down the mining operation. Fortunately, application of some traditional and custom-made noise mitigation measures solved the noise problem and allowed the mining operation to proceed
around the clock. At the time of writing this abstract, 1 Bitcoin = $46,500.
Modeling acoustic impedance and atmospheric absorption around airports using high-fidelity weather data
Authors: Shaw Emma , Sparrow Victor
Published: July 2022

It is known that environmental factors have an impact on the propagation of noise and as such, the integration of high-fidelity meteorological data into noise modeling programs has given hope for improved predictions of outdoor noise level, particularly in the field of aircraft noise.
Through the use of these high-fidelity weather data sets taken over a specific region surrounding an airport, there is an ability to calculate adjusted coefficients for the acoustic impedance and atmospheric absorption of the environment in external programs. These new calculations offer insight
into whether more formal noise modeling programs will benefit from the use of these high-fidelity meteorological files and how the accuracy of future aircraft noise predictions will be affected. [This research was funded by the U.S. Federal Aviation Administration Office of Environment and
Energy through ASCENT, the FAA Center of Excellence for Alternative Jet Fuels and the Environment, project 62 through FAA Award Number 13-C-AJFE-PSU under the supervision of Chris Hobbs. Any opinions, findings, conclusions or recommendations expressed in this material are those of the authors
and do not necessarily reflect the views of the FAA.]
Large-scale anechoic characterization of small caliber firearm impulse noise
Authors: Campbell Steven , Wall Alan , Taylor Corey , Mobley Frank , Rasband Reese
Published: July 2022

Three-dimensional source characterization is crucial for determining noise metrics produced by operating a firearm in indoor environments. Anechoic measurements for sound power and directivity measurement are challenging for small caliber firearms. In order to create high fidelity source
models of an M4A1 firearm (firing blanks), a team from Ball Aerospace, Inc., the Air Force Research Laboratory, and Brigham Young University conducted an expansive characterization within an anechoic facility located at the Owens Corning Acoustic Research Complex using a two-meter spherical
microphone array centered on the muzzle of the weapon. The array consisted of a quarter sphere of over forty microphones at various elevation and azimuth angles. By rotating the weapon, an entire closed sphere of over one hundred points were sampled with multiple shots. Differences in directivity,
sound power level and shot to shot repeatability are examined for two weapon configurations. These differences reinforce the idea that accurate source characterizations are required for modelling small caliber firearm noise propagation. The views expressed are those of the author and do not
necessarily reflect the official policy or position of the Department of the Air Force, the Department of Defense, or the U.S. government.
Revitalising soundscape of 'holy cross' sacred grove - baradi, goa: acoustic environment's affective and metaphysical heritage
Authors: Tavares Menino Allan S.M. Peter
Published: July 2022

Pilgrims throng to the sacred grove of Holy Cross Baradi to be revitalised by the 'metaphysical' experience of this hill-top space. This study soundscapes 'Holy Cross' sacred grove as a 'Revitalising space' extrapolating and complementing ISO/TS 12913-1/2/3 methods to connect the auditory,
affective and meta-physical perceptions of the acoustic (natural/human/machine/live-performance) environment. 'Background noise levels' (LA90) ranged between 36dB-43dB. Amongst significant results, 'natural' sounds were found more loud, clear, tonal, intimate, pleasant and eventful and evoked
better 'heightened awareness', as compared with other 'incidental' sounds and were perceived as more intimate, less loud, less pleasant, less eventful as compared with 'live performance'; Amongst significant relationships for 'natural sounds' perceptions: acoustical 'heightened awareness'
and 'harmony' multiregressed with subjective impressions of loudness, clarity, tonality and intimacy; acoustical 'eventfulness' was predictable from 'clarity' and 'tonality'. Amongst significant relationships for 'live performance' perceptions: acoustical 'pleasantness', 'eventfulness' and
'inspiration' multiregressed with subjective impressions of loudness, clarity, tonality and intimacy; 'heightened awareness' was predictable from 'loudness'; 'stillness' was predictable from loudness, tonality and intimacy respectively; 'harmony' was predictable from loudness, clarity and
intimacy respectively. The 'context' was perceived as optimally 'revitalising' (mean=4.71 on a scale of '+1 to '+5').
Predicting and visualizing duct borne noise with building information modeling software
Authors: Underwood Samuel , Wang Lily
Published: July 2022

This paper presents a proposed workflow to expedite duct borne noise calculations using Building Information Modeling (BIM) software. Duct parameters for a user-specified path are automatically extracted from an Autodesk Revit model with a Dynamo script. Insertion loss values for individual
duct elements and resulting receiver sound pressure levels are predicted according to Chapter 49 of the ASHRAE Handbook - HVAC Applications. Expanding on the authors' previous work in this area, new ideas for visualizing calculation results are explored, and predicted receiver sound pressure
levels are compared to in situ measurements in a practical case study of this approach. Results from this project support the continued development of more accurate and user-friendly noise control prediction tools for consultants and educators.
Acoustic and structural damping properties of fibrogranular composites made of jute and crumb rubber
Authors: Mohanty Amiya , Kumar Raja
Published: July 2022

Synthetic materials are mostly used in sound absorption and structural damping that cause harm to the environment and living beings. Previous studies have shown that jute and jute-derived composites are excellent sound-absorbing fibrous materials. The recent study also shows that the
inclusion of granular particles like crumb rubber in the fiber enhances sound absorption. Fibrogranular material of natural and recycled material is an alternative to synthetic material. This study aims to characterize the effect of granular material, i.e., crumb rubber with the jute fiber,
to understand the effect of granular particles on the jute fiber for sound absorption and the structural damping properties. Further, the size of crumb rubber is varied to understand its effect on the sound-absorbing and structural damping properties. The impedance tube transfer function method
is used to measure the acoustic properties for normal incidence of sound. Then the measured acoustic properties are used to inverse characterize using the classical porous material model to evaluate the non-acoustic parameters, which is further used to characterize the structural damping properties
based on the existing methodologies. The study discusses the sound absorption and structural damping properties of jute and crumb rubber fibrogranular composite
Speedup of FTMM (finite-size transfer matrix method) calculations through machine learning techniques
Authors: Burns Tom
Published: July 2022

Current methods to calculate the random incidence absorption of a finite size porous sample require complicated numerical integrations. An effort was made to replicate the FTMM (Finite-Size Transfer Matrix Method) using machine learning algorithms. A script was developed to generate
5000 normal incidence and FTMM solver files of 1 or 2 layer composites ranging from 5 to 100 mm on a commercially available solver. The FTMM sample size was 8'x9', as is used in the ASTM C423 standard. Various machine learning algorithms were then trained on half the dataset. The frequency
and complex normal incidence impedance were used as inputs, and the FTMM C423 result was the output. The best result produced was a 7-layer neural network with a mean deviation of .03 from the full dataset after 1000 rounds of training, with significant faster computation compared to the commercial
FTMM solver.
Warmstarting the constrained optimal filter design problem for active noise control systems in conic formulation
Authors: Zhuang Yongjie , Mo Zhuang , Liu Yangfan
Published: July 2022

In practical active noise control (ANC) systems, constraints such as stability, need to be considered in the controller design process. The optimal control filters can be obtained by solving a constrained optimization problem, which requires a significant computational effort. Recently,
a convex formulation in conic form was proposed for ANC applications which was shown to result in a computational time reduction by several orders. It is desirable to further improve its efficiency so that the optimal filter design process can be continuously repeated to achieve adaptive control
for slow varying operating conditions. One potential way is to introduce a warmstart technique where the filter solution of a similar system or environment is used as the starting point of the optimization algorithm. However, the conic formulation should be solved by the interior-point method
which, in general, is challenging for applying warm start techniques. In the current work, modifications are proposed to the original ANC filter design formulation so that the warmstart techniques can be applicable. The performance of warmstarting technique is investigated. Results show that
an appropriate choice of warmstart strategy can significantly reduce the number of iterations required for solving the proposed conic formulation of ANC filter design problem.
The application of tuned mass dampers to the Tire Pavement Test Apparatus to minimize the impact of rig resonance
Authors: Choo Kyosung , Choi Won Hong , Bolton J. Stuart , Black Matthew , Woo Sangbeom
Published: July 2022

The 'Tire Pavement Test Apparatus (TPTA)' at Purdue University is a device that was originally developed to study a tire's air-borne noise radiation in the frequency range 300 Hz to 2 kHz. However, in recent years, the device has mainly been used to quantify a tire's contribution to
structure-borne noise by measuring the force and acceleration at the hub. Hence, the frequency range of interest has shifted to frequencies below 300 Hz. By comparing measurements and FE simulations, undesired vibration was observed around 160 Hz in the measurement data. It was speculated
that the rig supporting the tire exhibits resonant vibration in a frequency range that hinders the measurement of tire force in that range. To identify the cause and mechanism of the rig resonance, Experimental Modal Analysis (EMA) was performed. In addition, to mitigate the influence of rig
resonance, tuned mass dampers commonly used in vehicle suspension systems were applied to the connecting arms of the TPTA. Careful adjustments of their mass and stiffness were performed to maximize vibration suppression performance by matching the major natural frequency of the TPTA support
arms. As a result, significant vibration attenuation could be achieved, which has made it possible to highlight the pure tire effects in the measurement data.
Dynamic mechanical analysis of rubber based products in under ballast mat rail applications
Authors: Bradley Colin , Havin Josh , Musafere Faiz
Published: July 2022

Rubber has long been a material used for vibration isolation in railroad applications due to the attractive material performance and environmental stability. In addition to the inherent sustainability benefits relative to alternatives, rubber in particular offers the opportunity for
further material engineering by controlling particle size distribution, density, binder properties etc. at the manufacturing stage and has found widespread use globally in under ballast mat applications from tramway to heavy-haul/mainline track types. In this paper we explore in detail the
basic vibration isolation properties of a variety of rubber based ballast mats via dynamic mechanical analysis and connect fundamental properties such as dynamic modulus, natural frequency, degree of damping to the relevant design criteria defined in widely accepted industry standards DIN
45673-5 and the more recent EN 17282.
Application of stockbridge type tuned mass damper on the chillers for mitigating the Tonal structure-borne noise in Hotel Guest Room under the Chiller Plant Room
Authors: Cheung Neo , Law Jackel , Tang Yu Tin
Published: July 2022

A tonal structure-borne noise was generated in a hotel room due to the vibration transmitted from the chiller above. The tonal structural-borne noise was annoying to the hotel guest in particular during bedtime. To develop a simple and cost-effective solution to solve this noise problem
without interrupting the operation of the chillers and altering the structure of the area, the prototypes of Stockbridge type Tuned Mass Damper (TMD) were fabricated for the chillers. The tonal vibrational force on the chiller and the coincident tonal noise in the guestroom was significantly
reduced.
Highlights of aeroacoustic tests of a metal spacecraft cabin ventilation fan prototype
Authors: Stephens David , Goodman Jonathan , Buehrle Rebecca , Mirhashemi Arman , Koch Lisa , Shook Tony , Sutliff Daniel , Allen Christopher , Matty Christopher
Published: July 2022

A metal spacecraft cabin ventilation fan suitable for aerodynamic and acoustic ground tests was designed and tested in the NASA Glenn Research Center Acoustical Testing Laboratory. The fan design featured a low-noise blade-vane count that was chosen to reduce the rotor-stator interaction
tone noise. The fan was throttled through its operating range, and results indicated that the measured aerodynamic and acoustic performance was in good agreement with predictions. Recommendations for further research of quiet high-performance fans intended to support long duration human space
exploration missions are offered. This small fan aerodynamic and acoustic test rig and the NASA Glenn Acoustical Testing Laboratory are valuable resources available for supporting NASA's aeronautics research and space exploration missions.
A case study in building HVAC systems noise control for the air-conditioning retrofit of a historic theatre
Authors: Sevener Nathan
Published: July 2022

The art deco Egyptian Theatre in DeKalb, Illinois, is one of only 5 remaining 'Egyptian' theatres in the United States. This 1400-seat theatre opened in 1929 with a program that was part motion picture house and part vaudeville theatre. In the present day, the theatre is owned and operated
by a non-profit organization and hosts a full schedule of community events, national touring acts, and films. Until the recent renovation and installation of air-conditioning, these events were halted during the hot summer months. The constraints imposed by the existing constructions complicated
the heating ventilation and air-conditioning system design and presented challenges for the acoustical analysis. This paper describes the noise mitigation that was designed into the theatre's new heating ventilation and air-conditioning system. It presents the challenges of retrofitting the
historic building and the noise control analysis that was performed. It concludes with a presentation of the noise levels that were achieved.
Rooftop acoustic barrier design without the need for roof penetrations
Authors: Bolduc Michael , Rajasekaran Jagannath
Published: July 2022

Sound barriers are a common noise mitigation design solution to limit the emissions of rooftop equipment in noise sensitive locations. Adding a rooftop barrier, however, adds additional structural concerns including additional dead loads transferred to the roof that need to be considered.
The industry-accepted practice is to connect the rooftop screen via fixed connections to the supporting structure below the roof line. This process can result in additional cost risk and may require involvement from several parties/sub-contractors throughout the installation process. Notable
costs include scanning the existing roof structure for existing structural steel members/potential interferences, cutting holes at fixed member locations, properly levelling the fixed connections, and patching/roofing the holes. This paper investigates an application of rooftop sound barriers
that requires no roof penetrations. These barriers are customizable and come in modular sections. The methodology of applying these customizable barriers is discussed along with their benefits and limitations within industrial/commercial applications.
INNOVATION MANAGEMENT ENTREPRENEURIAL ACTIVITY
Authors: Kulakova L. , Popova O. , Matveev V.
Published: July 2022

The innovative activity of entrepreneurial structures in Russia does not meet the requirements of the modern level of scientific and technological progress. One of the reasons for this appearance is an unfavorable economic climate, characterized by the underdevelopment of the institutional and infrastructure environment, market conditions and business conditions, the need for knowledge and technology from the business community, and the creativity of the pre-resiners. At the same time, for modern domestic entrepreneurship, the characters are weak with the main contingent of its stakeholders, which is why the consideration of the requirements and capabilities of the main part of potential partners is difficult. The proposed al-city development of the strategy and tactics of innovation in entrepreneurship will eliminate identified flaws. The subject is the socio-economic processes and relations that arise in the process of managing innovation in entrepreneurial activity. The direction of the study is the definition and methodological justification of the approach to the development of an innovation management policy in entrepreneurial activity in the context of an unfavorable innovative climate based on a stakeholder approach. The purpose of the study is to justify the influence of the innovative climate and accounting for the interests of the main stakeholders on innovative activity and innovative policy of entrepreneurial structures. Development of an algorithm for the formation of an innovative strategy and tactics of the company. In the process of research, general scientific (analysis and synthesis, induction and deduction, analogy, generalization) and special (monographic, statistical-economic, abstract-logical) methods of scientific knowledge were used. Based on the analysis of the innovative climate formed in the conditions of the formation of Industry 4.0, the need to take into account its key parameters in the development of strategy and tactics for managing innovation in entrepreneurial activity is substantiated. The influence of relationships with internal and external stakeholders on the activity and success of innovative processes in business structures has been clarified. The algorithm for developing a strategy and tactics for managing innovations in entrepreneurship has been developed and substantiated. Promising mechanisms for the activation of innovative activity in internal development are substantiated. The results of the study can be used by the legislative and executive state authorities, the academic community in the development of areas of improving the innovative climate, as well as business entities for the development and development of internal policy of innovation management.
Self Decipline in Mudhumozhi Kanchi
Authors: M Jagathambal
Published: July 2022

Mudumozhikanchi, written by Madurai cuddalore, has distanced itself from the actions of all the pepoles of the world. In kurattalisai, the old languages in the cult are for the benefit of the people. Emphasizes the actions of the superiors and does not condemn the actions of the subordinates. But the human has best described every aspect of human life as a gift, home, education, material virute, friendship, morality, and physicality. Poverty of human life lies in the fact that if these are not consistent then poverty willensue Mudumolikanchi is the best life guide in the world, highlighting the virtues of life that are relevsant in all ten chapters, to all time.
Improvement of Molecular Genetic Diagnostics of Infections Caused by Mycoplasma Pneumoniae and Chlamydia Pneumoniae
Authors: Глинкина Т.В.
Published: July 2022

Цель. Усовершенствовать метод выявления ДНК Mycoplasma pneumoniae и Сhlamydia pneumoniae с использованием полимеразной цепной реакции в режиме реального времени на основе выбора оригинальных праймеров и проб для качественной, количественной и дифференциальной диагностики инфекций.Материалы и методы. Методологический подход включал выбор специфических последовательностей из геномов Mycoplasma pneumoniae и Сhlamydia pneumoniae для дизайна праймеров и проб, создание положительного контрольного образца, подбор условий амплификации; апробация метода проведена на образцах ДНК, выделенных из соскобов эпителиальных клеток из полости носа, ротоглотки и мокроты детей с бронхитами и пневмониями.Результаты. Усовершенствован метод на основе мультиплексной полимеразной цепной реакции в режиме реального времени, характеризующийся высокой аналитической чувствительностью – 10 копий ДНК Mycoplasma pneumoniae и Сhlamydia pneumoniae на реакцию, и специфичностью, составившей 100%.Выводы. Данный метод позволяет одновременно проводить выявление ДНК Mycoplasma pneumoniae и Сhlamydia pneumoniae и определять концентрацию ДНК Mycoplasma pneumoniae в мокроте.

Purpose. Optimize the detection of Mycoplasma pneumoniae and Сhlamydia pneumoniae by real-time polymerase chain reaction on the base of the choice of original primers and probes for qualitative, quantitative and differential diagnostics of infections.Materials and methods. The methodological approach included the development of primers and probes specific for genome sequences of Mycoplasma pneumoniae and Сhlamydia pneumoniae, positive control DNA template, polymerase chain reaction conditions; the method was tested on DNA samples isolated from nasopharyngeal swabs and sputum of children with bronchitis and pneumonia.Results. The optimized method is based on the real-time multiplex polymerase chain reaction, the method’s analytical sensitivity is 10 copies of each Mycoplasma pneumoniae and Chlamydia pneumoniae DNA per reaction, and specificity – 100%.Conclusions. The optimized method gives the possibility to detect simultaneously Mycoplasma pneumoniae and Chlamydia pneumoniae DNA and determine the concentration of Mycoplasma pneumoniae DNA in sputum.
Clinical Significance of the Study of the Association of Allelic Polymorphism of Genes as Predictors of the Development and Unfavorable Course of Sepsis (Analytical Review of the Literature)
Authors: Сергиенко Е.Н. , Романова О.Н. , Фомина Е.Г. , Григорьева Е.Е. , Зверко В.В.
Published: July 2022

Сепсис представляет собой осложненное развитием бактериальной инфекции проявление синдрома системного воспалительного ответа, течение которого сопровождается угрожающей жизни органной дисфункцией, вызванной особенностями реакции иммунного ответа на инфекцию. Несмотря на современные стратегии реанимации и достижения в медицине, сепсис и его последствия остаются частой причиной смерти пациентов с внебольничными и внутрибольничными инфекциями. Поэтому для его ранней диагностики и оказания своевременной лечебно-диагностической помощи пациентам требуется использование информативных диагностических маркеров с целью выявления пациентов с высоким риском заболевания. Все больше данных свидетельствуют о том, что генетические вариации, особенно однонуклеотидные полиморфизмы (SNP) в целом ряде генов, ответственных за врожденный иммунитет, могут влиять на риск развития у пациентов серьезной инфекции. Определение различий в генах и связанных с ними различий в реакции на сепсис может способствовать разработке новых генетически адаптированных диагностических и терапевтических вмешательств для улучшения результатов лечения пациентов с восприимчивостью к сепсису.

Sepsis is a pathological condition with the development of life-threatening organ dysfunction caused by a violation of the regulation of the immune response to infection. Despite modern resuscitation strategies and advances in medicine, sepsis and its consequences remain a common cause of death in patients with community-acquired and nosocomial infections. Therefore, for its early diagnosis and timely care, prognostic markers are needed to identify high-risk patients. More and more evidence suggests that genetic variations, especially single nucleotide polymorphisms (SNPs) in a number of genes responsible for innate immunity, may affect the risk of serious infection in patients. The identification of differences in genes and related differences in response to sepsis may contribute to the development of new genetically adapted diagnostic and therapeutic interventions to improve outcomes if treatment in patients with sepsis susceptibility.