bluuebunny/crossref_metadata_2025 huggingface dataset:
Measurement and Analysis of the Half-Life of Some Viable Anti-Malaria and Analgesic Drugs
Authors: Aboyi A.B. , Tyowua S. T. , Iortyom E. T. , Hemen T. , Akosu D.D.
Published: October 2022

This paper is experimental research which focuses on the determination of the pharmaceutical half-life of some analgesic and anti-malaria drugs using the volume of distribution and clearance of the pharmacokinetic processes. Some analgesic and anti-malaria drugs were collected and administered to six healthy young men. Blood and urine samples were collected from each of them after one hour from the time of administration. All the samples for each drug were separated using a Gas chromatography machine to obtain the amount of drug remaining in the blood and the amount eliminated. The obtained values for the volume of distribution (Vd) from the blood samples and clearance (Cl) from the urine samples where mathematically evaluated with the elimination rate constant k=0.693 approximated to 0.7 to give a result with little or no error. The half-life for all samples were obtained and the pharmacokinetic properties and interactions of the drugs analysed. The various half-life obtained from this research certifies and correspond to the manufacturer's published half-life for the analysed drug samples. The high volume of distribution of Tramadol hydrochloride 70l/kg-painkiller, paracetamol 65l/kg-painkiller and artesunate 50l/kg-anti-malarial shows that they are highly absorbed into the body system and are very strong medications. They do not leave the system quickly and affects the physiological state for a long period while the low volume of distribution processes of diclofenac 1.4l/kg-painkiller, arthemeter 11.5l/kg-anti-malaria and quinine 28l/kg-anti-malaria shows a low distribution rate of these drugs, and implies they are less strong medications and does not last long in the body with their relative rates of elimination; Diclofenac 0.895l/kg/hr., arthemeter 2.6l/kg/hr. and quinine 2.4l/kg/hr.
Link of Blood in Urine with Exercise
Authors: Jameel Areej , Shaukat Hurain , Hussain Syed Bilal , Qadir Muhammad Imran
Published: October 2022

f someone is doing hard exercises after some pause, it is most probably, blood in urine. In this study was about linkage of blood in urine with exercise in which total 100 students participated studied in Bahauddin Zakariya University, Multan, Pakistan. Hematuria is basically blood in urine and it causes some sever infection in urinary tract and also the test is performed to check the blood in urine.
Seasonal Variation in Parasitic Prevalence of Oreochromis niloticus from Upper River Benue, Mutum Biu, Taraba State, Nigeria
Authors: S. Omeji , R.A. Obande , S.E Ogaba
Published: October 2022

Seasonal variation in parasitic prevalence of Oreochromis niloticus from Upper River Benue, Mutum Biu, Taraba State, Nigeria was conducted using standard parasitological methods. 400 samples of varied sizes of Oreochromis niloticus consisting of 200 samples each in dry and rainy seasons were bought from fishermen at the Upper River Benue, Mutum Biu, Taraba State for a period of ten months and transported fresh to the Parasitology Laboratory, College of Veterinary Medicine, Joseph Sarwuan Tarka University, Makurdi (formerly called University of Agriculture, Makurdi) where they were sorted out into different sizes and sexes. Out of the 400 samples comprising of 200 samples each of Oreochromis niloticus collected in dry and rainy seasons, 211 (52.75%) samples were infested with 605 parasites. Out of the 200 samples collected in dry season, while 105 (52.50%) were infested with 327 parasites, in rainy season, 106 (53.00%) samples were infested with 278 parasites out of the 200 samples. Prevalence of infection (53.00%) was higher in rainy season than dry season with prevalence of infection of 52.50% whereas, percentage parasite load (54.05%) was higher in dry season than rainy season with the percentage parasite load of 45.95%. Among the parasite species in dry season, while Camallanus spp. was the most prevalent (22.02%) Ichthyopthirius multifilis was the least (3.67%). In rainy season, while Diphillobothrium latum was the most prevalent (19.07%), Ichthyopthirius multifilis was the least (1.44%). Among the external parts, while the gill had the highest percentage parasite load in both seasons, the least was recorded for fin and skin, respectively. Percentage parasite load was higher in the intestine than the stomach in both seasons though, there was no significant difference (p>0.05) recorded for percentage parasite load of both external and internal parts of the fish samples in both seasons. Male Oreochromis niloticus had higher prevalence of infection and percentage parasite load than the female though, there was no significant difference (p>0.05) in the prevalence of infection and percentage parasite load and the sexes in both seasons. Samples of Oreochromis niloticus with longer lengths and greater weight had higher percentage parasite load than the samples with shorter lengths and smaller weight.
How Painting Associates with Blood in Urine?
Authors: Azhar Kashmala Kalsoom , Siddiqui Narmeen , Hussain Syed Bilal , Qadir Muhammad Imran
Published: October 2022

If someone is painting lover then there must be chances that he/she is standing most of the time and can have chances of blood in urine. Blood release through urine known as hematuria. Gross hematuria is a condition in which we see the release of blood with urine. Microscopic hematuria is a condition in which we can’t see the blood release in urine. Kidney infection, bladder stone, excess walk and cancer are the main cause of hematuria. Age and family history are the main risk factor. Building block of painting is the basic elements of painting. There are six basic elements of painting which are color, tone, line, shape, space and texture. The heart of painting is color. Every color has many shades and tones. By playing with texture painting is the best medium. Those who have blood in their urine have lowest percentage regarding to like painting and those who have no blood in their urine have highest percentage level towards likeliness of painting.
Canadian Rheumatology Association Recommendations for the Screening, Monitoring, and Treatment of Juvenile Idiopathic Arthritis-associated Uveitis
Authors: Berard Roberta , Ng Hon Yan , Human Andrea , Piskin David , Dhalla Muhammed , Gottlieb Chloe , Batthish Michelle , Chédeville Gaëlle , Forest Christina , Fortin Eric , Gardiner Jane , Gerhold Kerstin , Jastrzebski Andre , Lang Bianca , Miettunen Paivi M.H. , Morgenstern Sabrina , Morin Marie-Paule , Rosenberg Alan , Rumsey Dax G. , Solarte Carlos E. , Tehrani Nasrin , Watanabe Duffy Karen , Pardo Pardo Jordi , Hazlewood Glen S. , Levy Deborah M.
Published: October 2022

Objective

To develop Canadian recommendations for the screening, monitoring, and treatment of uveitis associated with juvenile idiopathic arthritis (JIA).

Methods

Recommendations were developed using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE)-ADOLOPMENT approach. A working group of 14 pediatric rheumatologists, 6 ophthalmologists, 2 methodologists, and 3 caregiver/patient representatives reviewed recent American College of Rheumatology (ACR)/Arthritis Foundation (AF) recommendations and worked in pairs to develop evidence-to-decision (EtD) tables. A survey to assess agreement and recommendations requiring group discussion was completed. EtD tables were presented, discussed, and voted upon at a virtual meeting, to produce the final recommendations. A health equity framework was applied to all aspects of the adolopment process including the EtD tables, survey responses, and virtual meeting discussion.

Results

The survey identified that 7 of the 19 recommendations required rigorous discussion. Seventy-five percent of working group members attended the virtual meeting to discuss controversial topics as they pertained to the Canadian environment, including timing to first eye exam, frequency of screening, escalation criteria for systemic and biologic therapy, and the role of nonbiologic therapies. Equity issues related to access to care and advanced therapeutics across Canadian provinces and territories were highlighted. Following the virtual meeting, 5 recommendations were adapted, 2 recommendations were removed, and 1 was developed de novo.

Conclusion

Recommendations for JIA-associated uveitis were adapted to the Canadian context by a working group of pediatric rheumatologists, ophthalmologists with expertise in the management of uveitis, and parent/patient input, taking into consideration cost, equity, and access.
Management of Peripheral Arthritis in Patients With Psoriatic Arthritis: An Updated Literature Review Informing the 2021 GRAPPA Treatment Recommendations
Authors: Leung Ying-Ying , Korotaeva Tatiana V. , Candia Liliana , Pedersen Susanne Juhl , Molano Wilson Bautista , Ruderman Eric M. , Bisoendial Radjesh , Perez-Alamino Rodolfo , Olsder Wendy , Möller Burkhard , Grazio Simeon , Gudu Tania , Mody Girish M. , Pineda Carlos , Raffayova Helena , Rohekar Sherry , Goldenstein-Schainberg Claudia , Gutierrez Urena Sergio R. , Casasola Vargas Julio César , Meghnathi Bhowmik , Prasad Roopa , Richette Pascal , Miranda Jose Roberto S. , Malliotis Nikolas , Lindqvist Ulla , Simon David , Ezeonyeji Amara , Soriano Enrique R. , FitzGerald Oliver
Published: October 2022

Objective

We aimed to compile evidence for the efficacy and safety of therapeutic options for the peripheral arthritis domain of psoriatic arthritis (PsA) for the revised 2021 Group in Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) treatment recommendations.

Methods

A working group consisting of clinicians and patient research partners was convened. We reviewed the evidence from new randomized controlled trials (RCTs) for PsA treatment from February 19, 2013, to August 28, 2020. We used the Grading of Recommendations Assessment, Development, and Evaluation (GRADE)-informed approach to derive evidence for the classes of therapeutic options for 3 patient groups: (1) naïve to treatment, (2) inadequate response to conventional synthetic disease-modifying antirheumatic drugs (csDMARDs), and (3) inadequate response to biologic DMARDs (bDMARDs). Recommendations were derived through consensus meetings.

Results

The evidence review included 69 RCTs. We derived GRADE evidence for each class of therapeutic options and achieved consensus for the recommendations. For patients naïve to treatment, the working group strongly recommends csDMARDs (methotrexate, sulfasalazine, leflunomide) and phosphodiesterase 4 inhibitors, and emphasizes regular assessment and early escalation to achieve treatment target. bDMARDs (tumor necrosis factor inhibitors [TNFi], interleukin 17 inhibitors [IL-17i], IL-12/23i, IL-23i) and Janus kinase inhibitors (JAKi) are also strongly recommended. For patients with inadequate response to csDMARDs, we strongly recommend TNFi, IL-17i, IL-12/23i, IL-23i, and JAKi. For those who had prior experience with bDMARDs, we strongly recommend a second TNFi, IL-17i, IL-23i, and JAKi. The evidence supporting nonpharmacological interventions was very low. An expert panel conditionally recommends adequate physical activity, smoking cessation, and diet to control weight gain.

Conclusion

Evidence supporting optimal therapy for the peripheral arthritis domain of PsA was compiled for the revised 2021 GRAPPA treatment recommendations.
Identifying Axial Spondyloarthritis in Patients With Inflammatory Bowel Disease Using Computed Tomography
Authors: Lim Chong S.E. , Hamilton Louise , Low Samantha B.L. , Toms Andoni , Macgregor Alexander , Gaffney Karl
Published: October 2022

Objective

The diagnosis of axial spondyloarthritis (axSpA) is hampered by diagnostic delay. Computed tomography (CT) undertaken for nonmusculoskeletal (non-MSK) indications in patients with inflammatory bowel disease (IBD) offers an opportunity to identify sacroiliitis for prompt rheumatology referral. This study aims to identify what proportion of patients with IBD who underwent abdominopelvic CT for non-MSK indications have axSpA and to explore the role of a standardized screening tool to prospectively identify axSpA on imaging.

Methods

Abdominopelvic CT scans of patients with verified IBD, aged 18 to 55 years, performed for non-MSK indications were reviewed by radiologists for the presence of CT-defined sacroiliitis (CTSI), using criteria from a validated CT screening tool. All patients identified were sent a screening questionnaire, and those with self-reported chronic back pain (CBP), CBP duration of greater than 3 months, and age of onset of less than 45 years were invited for rheumatology review.

Results

CTSI was identified in 60 out of 301 (19.9%) patients. Out of these 60 patients, 32 (53%) responded to an invitation to participate, and 27 out of 32 (84.3%) were enrolled. Of these, 8 had a preexisting axSpA diagnosis and 5 did not report CBP. In total, 14 patients underwent rheumatology assessment, and 3 out of 14 (21.4%, 95% CI 4.7-50.8) had undiagnosed axSpA. In total, 11 out of 27 (40.7%, 95% CI 22.4-61.2) patients had a rheumatologist-verified diagnosis of axSpA.

Conclusion

In this study, 5% (3/60) of patients with IBD undergoing abdominopelvic CT for non-MSK indications with CTSI were found to have undiagnosed axSpA and, overall, 18.3% (11/60) were found to have axSpA. This reveals a significant hidden population of axSpA and highlights the need for a streamlined pathway from sacroiliitis detection to rheumatology referral.
Sex-Specific Differences in Patients With Psoriatic Arthritis: A Systematic Review
Authors: Coates Laura C. , van der Horst-Bruinsma Irene E. , Lubrano Ennio , Beaver Steph , Drane Emma , Ufuktepe Baran , Ogdie Alexis R.
Published: October 2022

Objective

A systematic review of published literature was conducted to collate evidence on sex-specific differences in clinical characteristics, disease activity, and patient-reported outcomes (PROs) in psoriatic arthritis (PsA), including response to treatment.

Methods

Searches of MEDLINE, Embase, and the Cochrane Database of Systematic Reviews were performed in November 2020 for observational studies of adults with PsA reporting outcomes by sex (published from January 1, 2015, to November 13, 2020). In addition, hand searches of systematic literature reviews and (network) metaanalysis bibliographies were performed. Searches ofClinicalTrials.govand congress abstracts from the European Alliance of Associations for Rheumatology, the American College of Rheumatology (ACR), and the American Academy of Dermatology (2019-2020) were also carried out. Eligible studies with 100 or more patients prespecified a comparison by sex and reported clinical characteristics and/or disease activity. Data extracted included patient characteristics, study design, baseline clinical characteristics, and disease activity results, including PROs.

Results

Database searching yielded 3283 unique records; 31 publications of 27 unique studies were included. The review found generally higher rates of peripheral disease in women, including higher tender joint counts. There was some evidence of more axial disease in men, plus greater skin disease burden. There were consistently no differences in Dermatology Life Quality Index scores, though across other PROs, women had worse scores, including pain and fatigue. Women had poorer responses to treatment, indicated by outcome measures such as ACR responses and minimal disease activity.

Conclusion

This review indicates that important differences exist between the sexes in PsA. However, the limited evidence for this conclusion underlines the need for additional research in this area.
Sex-Based Differences in Sonographic and Clinical Findings Among Patients With Psoriatic Arthritis
Authors: Furer Victoria , Wollman Jonathan , Levartovsky David , Aloush Valerie , Elalouf Ofir , Sarbagil-Maman Hagit , Mendel Liran , Borok Sara , Paran Daphna , Elkayam Ori , Polachek Ari
Published: October 2022

Objective

To investigate sex-based sonographic differences in patients with psoriatic arthritis (PsA).

Methods

The study population included consecutive prospectively recruited patients with PsA, as determined by the CASPAR (Classification for Psoriatic Arthritis) criteria, who underwent clinical and physical examinations, followed by a detailed ultrasound (US) evaluation (greyscale and Doppler). US evaluation included 52 joints, 40 tendons, and 14 points of entheses (Modified Madrid Sonographic Enthesis Index [MASEI] plus lateral epicondyles) performed by an experienced sonographer blinded to the clinical data. The US score was based on the summation of a semiquantitative score for synovitis, tenosynovitis, and enthesitis. The US enthesitis score was categorized into inflammatory lesions (ie, hypoechogenicity, thickening, bursitis, and Doppler) and structural lesions (ie, enthesophytes/calcifications and erosions).

Results

The study population of 158 patients included 70 males and 88 females. The males had higher rates of employment (P= 0.01), Psoriasis Area and Severity Index scores (P= 0.04), and mean swollen joint counts (P= 0.04). The total US score and its subcategory scores—the synovitis and tenosynovitis scores—were similar for both sexes, whereas the total enthesitis score and its subcategory score—the inflammatory enthesitis score—were significantly higher for the males compared to the females (P= 0.01 andP= 0.005, respectively). Hypoechogenicity, thickening, and enthesophytes were more prevalent in males compared to females (P< 0.05). Multivariate ordinal logistic regression models showed that male sex was associated with a higher US inflammatory enthesitis score compared to female sex (odds ratio 1.96,P= 0.02).

Conclusion

Sonographic enthesitis was more prevalent in males compared to females with PsA. These differences were not reflected by enthesitis disease activity scores derived from clinical assessment.
Le “Kaddish” in-fini et ininterrompu d’André Schwarz-Bart : jusqu’à une pièce de théâtre et un roman en pièces
Authors: Kaufmann Francine
Published: October 2022

André Schwarz-Bart n’a jamais eu la plume facile. Même ses livres édités ont failli ne jamais voir le jour. Il a d’ailleurs cessé de publier son œuvre personnelle après 1972, alors qu’il n’a jamais cessé d’écrire jusqu’à la fin de sa vie, en septembre 2006. Mais il détruisait au fur et à mesure ses manuscrits, non sans se remettre ensuite au travail, parfois sur le même projet, parfois sur un projet similaire. Cette étude se propose de chercher les raisons, biographiques et esthétiques, de ses luttes avec l’écriture. Elle tente d’expliquer l’inachèvement, mais aussi les recommencements perpétuels de son dernier projet, Kaddish, une pièce de théâtre et un roman, dont on trouve des milliers de traces : plans, épisodes, dialogues, enfouis dans ses cahiers, ses carnets et les pages annotées de ses livres.
Petrolio de Pasolini, un livre-somme inachevé ou inachevable ?
Authors: Colomb Chantal
Published: October 2022

Pasolini n’a pas pu terminer Petrolio, qu’il écrivait lorsqu’il fut assassiné dans la nuit du 1er au 2 novembre 1975. Tantôt appelé Roman, tantôt dénommé Poème, Petrolio n’est pas subdivisé en chapitres mais en appunti (notes), ce qui révèle que, pour Pasolini, aucune section du livre n’était achevée. Plusieurs modèles d’œuvres très longues l’ont inspiré : La Divine Comédie de Dante, les contes des Mille et une nuits ou encore À la recherche du temps perdu de Proust. Pasolini considérait Petrolio comme une œuvre-somme, il avait même dit que ce serait son dernier livre. Nous nous interrogerons sur la faisabilité du livre. Pasolini pouvait-il achever le livre tel qu’il l’avait conçu ? Dès le début du roman, il semble indiquer qu’il n’aura ni début, ni fin. La pluralité des narrateurs, la diversité des lieux, des époques ou la référence à des mythes permettent à Pasolini d’élaborer toute une poétique de l’inachèvement. Mais reste la question du sens du livre. Il semble que Pasolini ait voulu entrelacer les significations politique, sexuelle et mystique de son livre, ce qui renforce sa complexité.
Le journal de René Depestre peut-il faire œuvre ?
Authors: Cauvin Gaëlle
Published: October 2022

Un démarrage difficile caractérise le journal cubain de René Depestre : l’écrivain se plaint de n’avoir pas commencé plus tôt à le tenir, doute de son entreprise et écrit sporadiquement. L’homme traverse une crise existentielle dont le journal peut témoigner. Cependant, les pages manuscrites montrent une certaine obstination, une volonté de faire œuvre, sans même parler de la version tapuscrite établie par ses soins. Et la morale de René Depestre ? Si elle fut un frein, c’est elle qui lui a permis de finir ce qu’il avait entamé, et de dénouer ses difficultés de vie.
Le monologue épistolaire, poétique de l’inachèvement dans Confiteor
Authors: Doig Katherine
Published: October 2022

« J’ai considéré ce roman comme définitivement inachevé le 27 janvier 2011 » : ainsi s’ouvre la postface du romancier catalan Jaume Cabré à son Confiteor (Jo confesso, 2011, traduit par E. Raillard en 2013). Cette formule qui pointe, au-delà de la totalité d’une oeuvre publiée, l’infini du possible, résonne dans les préoccupations esthétiques et éthiques du roman. Malgré l’assiduité du narrateur, Adrià, à chercher l’exhaustivité, l’aboutissement, le point final, dans la longue lettre qu’il écrit pour “tout” dire à sa bien-aimée, l’univers littéraire les lui refuse : par le destin que Cabré lui impose (non pas la mort, mais Alzheimer), par la forme du monologue épistolaire dont le destin lui échappe néecssairement, par la confusion qui hante la fin de la diégèse. Cette impossibilité à aboutir se révèle comme une valeur littéraire : valeur réaliste, soulignant la continuité de la vie malgré les fins narratives qu’on lui impose ; valeur humaine, car, comme le souligne la forme de la lettre, le roman est un appel à la réinvention permanente ; valeur éthique, car cette ouverture s’oppose aux systèmes totalisants et totalitaristes, aux solutions finales qui, chez Cabré, représentent le Mal.
En finir enfin avec l’in-fini ?
Authors: Dugas Guy
Published: October 2022

Comment suivre le cheminement d’un texte depuis ses premiers linéaments, au fil de ses errances, de ses erreurs et de ses repentirs, jusqu’à sa publication, quand toute notre éducation ne nous donne a lire et à étudier que des œuvres achevées ? Pour un de ces ouvrages admirés par des générations d’élèves ou d’étudiants, combien de textes du même auteur avortés, inachevés, inaboutis ? Le droit à la réécriture de ses textes, que Barthes reconnaît à tout écrivain, est-il illimité ? Sinon quelle limite peut-on lui donner – quel droit pour ceux que l’on nomme les ayants droit, précisément, détenteurs par voie légale de l’archive d’un écrivain ?Au bout du compte, toutes ces questions se limitent à une seule et même interrogation : comment analyser toute démarche créative, par essence in-finie, à l’aune de l’oeuvre achevée ?
Vers une esthétique du vivant en temps d’extinction  : le rôle de l’art ou l’art de faire connaissance
Authors: Paiva Joshua de
Published: October 2022

Interrogeant l’idée que seul un art anesthétique saurait jouer un rôle face aux urgences écologiques, l’enquête sur la rencontre sensible avec les vivants – et son potentiel de transformation de l’attention – chez Tomás Saraceno et Marguerite Humeau invite à réévaluer les enjeux possibles de l’art et, à l’horizon, d’une esthétique du vivant en temps d’extinction – à condition de prendre au sérieux la dimension expérientielle de la crise actuelle, et de repenser les rapports entre sensibilité et action.
Partages de l’écoute  : l’art écologique de Félix Blume
Authors: Dujardin Fanny
Published: October 2022

Que peut l’art sonore, à l’ère de la crise écologique  ? Le sonidista Félix Blume, preneur de son et artisan de l’écoute, répond ingénieusement à la question. En créant des situation de partage de l’écoute, il transforme nos manières de prêter attention à notre milieu et aux autres êtres qui le peuplent. Il permet ainsi de penser, avec Vinciane Despret, que l’anthropocène est aussi un «  phonocène  » propice à la redécouverte des sons de la terre et des chants des autres qu’humains.
La possibilité d’une nouvelle symbiose
Authors: Bessette Juliette
Published: October 2022

Cet article analyse comment la notion de symbiose, issue du domaine de la biologie, a été détournée de son premier champ d’application, notamment dans le contexte de la culture cybernétique aux États-Unis dans les années 1960. Il clarifie la portée historique de ce détournement métaphorique, puis s’arrête sur deux cas d’étude contemporains à travers lesquels designers et artistes s’approprient à leur tour le concept afin de questionner la pertinence de ces transpositions.
Des prototypes d’action pour le futur
Authors: Raffard Matthieu , Roussel Mathilde
Published: October 2022

L’urgence planétaire de notre situation écologique nous oblige à effectuer un changement radical de paradigme si nous voulons survivre aux crises qui se présentent devant nous. Pour cela nous n’aurons probablement pas le temps d’inventer intégralement les gestes, les outils, et les attitudes dont nous allons avoir besoin. Il nous semble que certains artistes à travers leur travail peuvent nous aider à repérer les «  prototypes d’actions  » qui nous serons nécessaires.
Zona da Mata
Authors: Magalhães Ana , Bogéa Marta , Alves Cauê
Published: October 2022

Dans cet article, nous présentons le projet de l’exposition Zona da Mata, organisée par le Musée d’Art Contemporain de l’Université de São Paulo (MAC USP) et le Musée d’Art Moderne de São Paulo (MAM), entre mai 2021 et mai 2022. Il s’agit d’une exposition d’art et d’architecture contemporaines qui a considéré des œuvres et des projets en reconnaissant la contribution des peuples autochtones et des communautés diasporiques de l’Afrique, au regard de la construction de l’idée de paysage et les rapports entre culture et nature au Brésil.
MICRO, SMALL AND MEDIUM ENTERPRISES ACCESS TO FINANCE CONSTRAINTS IN ETHIOPIA: DEMAND SIDE ANALYSIS
Authors:   Addis Ababa University, Addis Ababa, Ethiopia, Wajebo Temesgen Woldamanuel
Published: October 2022

Despite the immense importance of micro, small and medium enterprises (MSMEs) to job creation and the alleviation of abject poverty, significant numbers of MSMEs cannot realize their full potential because of limited access to finance and other factors, mostly in developing countries. The study investigates micro, small and medium enterprises' access to finance constraints in Ethiopia from a demand-side perspective. This study employed a descriptive analysis using survey data collected from 814 randomly selected sample enterprises. The results show that about 76% of the MSMEs were established by initial capital majorly generated from their own savings, family or friends, Equub, and saving and credit cooperatives among others. The remaining 24% accessed their initial capital from formal financial institutions. From the total, 39.4% of MSMEs did not apply for loans due to high collateral requirements, complex application procedures, unfavorable interest rates, insufficient loan size, maturity, and grace period, and lack of transparency. The study results also reveal that 22%, 46%, and 32% of the MSMEs are partially credit constrained, fully credit constrained, and non-credit constrained, respectively. The difference between the average demand and the loan supplied is estimated to be 3241, 11444, and 30949 USD for each micro, small, and medium-sized enterprise, respectively. The total estimated finance gap for all MSMEs is 31.7 billion USD. The findings of this study suggest the establishment of public credit guarantee schemes, cash flow-based lending, and psychometric testing for credit scoring and automating the MFIs' services to improve MSMEs' access to finance.
A Study on Success Motivation and Academic Engagement of Teenage Students Suffering from Test Anxiety
Authors: Mugundharajan E.
Published: October 2022

This study aims to study success motivation and academic engagement of teenage students suffering from test anxiety. Quantitative methods will be employed in his investigation, and broad research questions will be posed. Systematic random selection will be used to choose participants, and questionnaires will be used to collect data for the study. A sample of 500 young individuals who are now enrolled in educational institutions will be used as responders. The collected data will be analyzed using SPSS, the Statistical Package for the Social Sciences.
Docking Study of Altered Nelfinavir & Indinavir with Protease of Human Immunodeficiency Virus
Authors: Qadir Muhammad Imran , Fatima Kiran , Munir Ayesha , Hussain Syed Bilal
Published: October 2022

Nelfinavir and Indinavir are protease inhibitors that function against HIV-1 (HIV-1). Protease inhibitors act by preventing HIV's protease enzyme from functioning. Infectious HIV-1 protease enzyme is proteolytic enzyme in nature that transforms virus causing polyprotein precursors into particular functional proteins. Nelfinavir and Indinavir bind to the protease's active site and prevent it from working. This inhibitor prevents the breaking of virus causing polyproteins, preventing the growth of immature and the non-infectious virus causing particles. However, protease inhibitors are always utilized with at least two further drugs which are anti-HIV drugs. Using the pubchem database from NCBI, we used docking techniques to find the structures of Indinavir and nelfinavir. Then used ds4.1 to modify it then open in auto dock or pay mole to see their attachment after docking with protein.
To Evaluate the Link Between Ketones in Urine and Perfume Allergy
Authors: Rukh Mah , Naeem Aqsa , Hussain Syed Bilal , Qadir Muhammad Imran
Published: October 2022

This study presents the relation between perfume allergy and presence of ketones in urine. When glucose level is low in our body or we don’t have enough insulin to absorb glucose then our body compensate by start breaking fats to provide energy and ketone are produced as a byproduct. The normal value of ketone in urine is less than 0.06mmol/L. Ketones are normally present in blood and urine but an increased value shows acidosis that can be fatal. Some people love scents. Perfumes contain certain chemicals that can cause allergy. The most common one is contact allergic dermatitis. The most common symptoms of perfume allergy are headache, difficulty in breathing, wheezing, chest tightening, asthma and stuffy nose. The present study shows that 25% males have Ketones in urine and are also allergic to perfumes while 2.25% females have ketone in urine and also allergic to perfumes.
Influence of Lizard Fright on Urine Bilirubin Level
Authors: Tahir Ayesha , Aslam Rabbia , Hussain Syed Bilal , Imran Qadir Muhammad
Published: October 2022

The basic intention behind this study is to check any influence of lizard fright on the concentration of bilirubin within urine. Many subjects participated in this study. Many persons possessed lizard aversion but there is no possibility of any relation between both of them.
ANÁLISE TÉCNICA DA INTEGRAÇÃO DE SISTEMAS FOTOVOLTAICOS EM EDIFICAÇÕES DA UFMS
Authors: Pereira Priscila Martins Mateus de Oliveira , Neto Luiz Pereira da Silva , Marcio José Sorgato
Published: October 2022

O estudo tem o objetivo de analisar a viabilidade econômico-financeira da inserção de energia solar fotovoltaica como alternativa de investimento capaz de proporcionar a redução dos custos decorrentes do consumo de energia elétrica possibilitando uma residência ecologicamente mais sustentável. Para tal, foi realizado um estudo de caso com uma análise estatística utilizando o histórico de consumo do período de Janeiro de 2013 a Dezembro de 2017 para determinar o perfil de consumo de uma residência de classe média baixa localizada no município de Serra-ES onde foram avaliados os investimentos necessários e seus respectivos tempos de retorno de investimento. Os estudos demonstraram que a implantação de energia solar fotovoltaica, embora tenha um elevado investimento inicial, é uma alternativa viável tanto do ponto de vista de investimento quanto como redução de custos, além de ser uma alternativa sustentável que auxilia na preservação do meio ambiente. (Trabalho final de curso)
Cognizance of Color Blindness in University-Girls-Hostel Residents
Authors: Qadir Muhammad Imran , Rasheed Asma , Hussain Syed Bilal
Published: October 2022

The main purpose of the study was awareness about color blindness, its causes and impact on health in university-girls-hostel residents. Eighty students joined in this study. All the students of Bahauddin Zakariya University Multan Khadija hall girl’s hostel were involved in that study in which they were asked about color blindness it provides answers like is color blindness a viral infection or a bacterial disease, metabolic disease. Any one of you your family and friends have ever suffered from this disease? How can we treat it with the use of medicines or surgery? It is shifted genetically or by blood transfusion contact. Which they were asked about color blindness disease type and it’s diagnose and how it can be controlled either by surgery or medicines or no need of its treatment and how it spreads and family friends history of this disease. A survey was done by the awareness about color blindness its reasons and effect on health. A survey was done by the awareness about color blindness its reasons and effect on health. The statistical analysis was done by using MS word. Above study showed that majority of students said that AIDS is a bacterial disease rather than fungal disease. 67.5% of students claimed it as a bacterial disease but 36.25% said that it is not a genetically transferred disease. 53.75% of students had this disease.
Development of an Artificially Intelligent Advising System for Saudi Medical Transcription
Authors: Khan Nayyar Ahmed
Published: October 2022

In this world of IT related services and computer science, various new technologies are emerging. This technology is focused mainly on the ease of human being and their survival amid Covid 19. Medical Transcription is one of the highly professional IT related services. It involves highly skilled data processing job for medical field. The common system which prevails around the world nowadays is to visit the hospital and get the cure. However, once a patient which is a hospital and gets the medicine which is diagnosed by a doctor. He comes back to his house and take the medicine to get well. But in this complete process there is no guarantee of responding to a medicine in such a manner such that the problem, which had arisen will not happen in the future. Thus, it becomes very obvious that we don’t have a solution in which the healthcare benefits can be obtained from using IT and services. As per the old system. The records of the patient’s health are maintained in a file normally for a good hospital. The system maintains the medical records for each patient, however medical record helps in avoiding chances of omission of some of the important findings in the records. But in this scenario of globalization across the world, mobility of human being had been a very important part of its daily lifestyle. Thus, we can very well say that the system which prevails around the world nowadays is not very easy. Since the files that are written in the hospital for the medical health care services is not approachable at a very convenient rate. It is also not at all very sure that the disease that had been cured by the doctor shall never revert back again. When the disease comes back again, the patient needs a date to visit the doctor. This type of free visit to the doctor is required at every instance whenever a man feel some sick-ness. The sickness that has been encountered by the human being is not at all mortal. It can return back whenever it is required and there are certain symptoms in which the disease can be observed. This is a loss of time and effort. It is a very strong understanding method and the use of artificial intelligence can be done in order to observe the routine of the person and its healthcare. A system could be designed in which depending on the past histories of the medical ailments and the treatment of a person can be utilized in order to predict the nature of its human anatomy. A system which is artificially so intelligent that it can be able to give prediction for what might happen in the future for a particular man. Thus, this artificial intelligence system will be helpful enough to give warning to a human being at various times whenever he is happy, so that he will be saved from the problems that might arise in the future.
Construcción del concepto de desarrollo sostenible mediante el recurso didáctico: huerta escolar
Authors: Herrera Ortíz Katia Elena , Zarco Fabricio Rafael
Published: October 2022

El presente artículo emplea la huerta escolar como recurso didáctico con el objetivo de construir el concepto de desarrollo sostenible, en los estudiantes de grados 4°, 5° 6° de las escuelas rurales de la comuna educativa n° 3 de la ciudad de Santa Marta, Magdalena – Colombia. Para ello, se empleó un diseño metodológico de investigación acción participativa bajo el paradigma sociocrítico y el enfoque cualitativo y un muestreo no probabilístico intencional. La muestra estuvo integrada por 30 estudiantes y 15 docentes incluyendo a 3 directivos a los cuales se les aplicó: cuestionarios semi estructurados, entrevistas y análisis documental; los criterios de inclusión fueron: escuelas oficiales de la comuna educativa 3 del distrito de Santa Marta, en la cual, hubiesen desarrollado durante los últimos 5 años algún proyecto de huerta escolar o proyecto ambiental dentro de las inmediaciones de la institución; se excluyeron 1°, 2° y 3° de primaria; al igual que los estudiantes del nivel educativo de secundaria. Los principales resultados permitieron reconstruir el concepto de desarrollo sostenible mediante el recurso didáctico de huerta escolar a partir de las vivencias que experimentaron los investigados durante el abordaje del marco de acción de esta investigación. Entre las principales conclusiones destaca que la implementación del uso de las huertas escolares se percibe como una serie de actividades tangibles: sembrar, cuidar y cosechar verduras; no obstante, no se le da el histórico cultural para empoderar a los estudiantes en la construcción colectiva de la soberanía alimentaria y la nutrición de calidad.
Relationship Changes Between Parents and Children of Modern Family During Covid-19 Pandemic in Hukurila, South Leitimur District, Ambon City
Authors: Manuputty Feky , Litaay Simona Christina Henderika , Murwani Prapti , Ramdhan Rizki Muhammad
Published: October 2022

The nuclear family has an important meaning in modern society. In Hukurila, South Leitimur District, Ambon City, generally families live a modern lifestyle, in which the relationships between parents and children are no longer carried out properly. This can be seen from the reduced parental supervision of their children at home. Parents are busy with various activities and conversely the children are also busy with their own activities. The aim of this research is to find out and explain the forms of changes in the relationship between parents and children in modern families during the COVID-19 pandemic. The method used is a qualitative research method by means of in-depth interviews and observations and uses secondary and primary data sources. This study found changes in the relationship between parents and children, namely the reduced parental supervision of children, the more distant the relationship between parents and children due to the social environment and millennial subculture and parents are seen as passing on only a few values ??of life to their children.
Implementasi Q-Gis dalam Pembuatan Aplikasi Peta Ketahanan dan Kerentanan Pangan Kota Salatiga Berbasis Web
Authors: Khusnuliawati Hardika , Sukmanaji Sukmanaji , Hari Saputro Al Hari Firdhaus
Published: October 2022

Kota Salatiga merupakan salah satu wilayah di Indonesia yang memiliki potensi kerawanan pangan.  Untuk menghadapi kondisi tersebut, diperlukan kajian yang mendalam Salatiga terkait kondisi pangan di daerah-daerah yang termasuk wilayah Kota Salatiga sehingga dapat diberikan pemantauan dan penekanan pada daerah yang rawan pangan. Akan tetapi, saat ini Kota Salatiga belum memiliki aplikasi yang dapat diakses secara umum dalam rangka menyediakan informasi ketahanan pangan yang yang akurat dan komprehensif. Maka dari itu dibangun Aplikasi Peta Ketahanan dan Kerentanan Pangan sebagai instrumen untuk memantau ketahanan pangan di wilayah Kota Salatiga. Pembangunan Aplikasi Peta Ketahanan dan Kerentanan Pangan menggunakan Sistem Informasi Geografis Q-GIS. Sistem Informasi ini digunakan untuk membangun Peta Kota Salatiga yang berisi informasi seperti Luas Lahan, Jumlah Sarana dan Prasarana Penyedia Pangan, Jumlah Rumah Tangga Sejahtera, Akses Jalan, Akses Air Bersih, Jumlah Tenaga Kesehatan, dan Komposit. Peta yang dihasilkan ditampilkan dalam suatu website sehingga dapat menjadi sumber informasi mengenai daerah yang rentan akan pangan bagi masyarakat maupun Dinas di Kota Salatiga. Berdasarkan hasil evaluasi, Aplikasi Peta Ketahanan dan Kerentanan Pangan dapat dioperasikan dengan baik dan mampu menyediakan informasi yang akurat.
Validasi penggunaan Panel Half Slab Precast pada Perencanaan Ruko di Sumatera Utara
Authors: Rahmadia Nirma , Tarigan Johannes
Published: October 2022

Salah satu inovasi dalam perencanaan dan pelaksanaan pekerjaan kontruksi masa kini adalah penggunaan sistem beton precast diantaranya adalah pelat lantai precast. Penggunaan pelat  lantai pracetak yang cukup sering digunakan adalah half slab precast. Pada penelitian ini, akan dilakukan simulasi pemodelan produk pelat lantai dan pelat atap menggunakan sistem half slab precast dengan penulangan one way slab pada fungsi ruko sebagai rumah tinggal dan perkantoran difokuskan untuk wilayah Sumatera Utara dengan 6 jenis tipe pelat, yaitu HS-1, HS-2, HS-3, HS-5 dan HS-6. Dengan simulasi pemodelan ini diharapkan tercipta produk half slab precast generasi Sumatera Utara yang dapat dipasarkan dan memenuhi kebutuhan konstruksi di wilayah Sumatera. Hasil dari penelitian ini yaitu tebal pelat rencana yang mengacu pada nilai minimum diperoleh dari kondisi pelat pada setiap kemungkinan kondisi tumpuan yaitu sebesar 16 cm. Momen terbesar terjadi pada pelat lantai tipe HS-3 dengan nilai momen 1388,45 kgm yang terletak pada tumpuan arah x. HS-3 memiliki dimensi total 650 mm x 300 mm, dengan dimensi half slab perparsial 124 mm x 290 mm. Besarnya lendutan yang terjadi pada pelat lantai dan pelat atap berdasarkan hasil analisis menggunakan software ETABS, memperlihatkan nilai lendutan sebesar 11,633 mm pelat lantai ruko yang difungsikan sebagai rumah tinggal, dan 15,131 mm pada pelat lantai ruko yang difungsikan sebagai perkantoran, serta 15,424 mm pada pelat atap, menunjukkan bahwa tipe baik pelat lantai ataupun pelt atap memenuhi persyaratan lendutan maksimum, sehingga dapat meminimalisir defleksi atau deformasi yang dapat berpengaruh negatif pada kekuatan atau kemampuan layan suatu struktur.
Perbandingan Agregat Halus terhadap Kuat Tekan Mortar Antara Pasir Awang Bangkal dan Pasir Barito
Authors: Yanuar Khairil , Ihsani Abdul Hafizh , Arya Anugerah Muhammad , Ruspiansyah Ruspiansyah , Suwaji Suwaji
Published: October 2022

Kemajuan bangunan konstruksi yang berkembang di Negara kita mempengaruhi banyaknya fungsi-fungsi bangunan yang beragam sehingga mengakibatkan kuantitas bangunan, percepatan bangunan yang diinginkan dan tuntutan akan kualitas konstruksi semakin tinggi. Mortar adalah suatu campuran yang terdiri dari Semen, Agregat Halus dan Air. Bahan perekat pada mortar dapat berupa Tanah Liat, Kapur, maupun Semen. Agregat Halus (Pasir) pada campuran mortar berfungsi sebagai bahan pengisi (Bahan yang direkat) baik dalam keadaan dikeraskan ataupun tidak dikeraskan. Penelitian Tugas Akhir ini dilakukan di Laboratorium Struktur dan Bahan Politeknik Negeri Banjarmasin.Pengumpulan data dengan cara yang dipakai untuk menghimpun, menelaah dan pengumpulan data-data atau sumber-sumber yang berhubungan dengan topik yang diangkat dalam suatu penelitian. Studi bisa didapat dari berbagai sumber, seperti jurnal, makalah, laporan, buku dokumentasi, internet (browsing) dan pustaka. Hasil kuat tekan terhadap umur mortar Pada umur 3 hari Semen Gresik Pasir Barito 6,05 Mpa, Pada umur 7 hari Semen Gresik Pasir Barito 6,05 Mpa, Pada umur 14 hari Semen Gresik Pasir Awang Bangkal 8,66 Mpa, Pada umur 28 hari Semen Gresik pasir Awang Bangkal 10,68 Mpa. Dapat disimpulkan bahwa Pasir Barito termasuk dalam zona IV dan Pasir Awang Bangkal termasuk dalam zona II. Berdasarkan hasil rata – rata kuat tekan mortar didapatkan hasil : Pasir Barito pada umur 3 hari sebesar 6,05 Mpa, umur 7 hari 6,05 Mpa, umur 14 hari 7,68 Mpa, dan umur 28 hari 9,56 Mpa, Pasir Awang Bangkal pada umur 3 hari sebesar 4,14 Mpa, umur 7 hari 4,75 Mpa, umur 14 hari 8,66 Mpa, dan umur 28 hari 10,68 Mpa.
Upaya Meningkatkan Pemahaman Menuju Proses Dunia Kerja Melalui Layanan Karir Metode Mind Mapping Pada Siswa Kelas XII-S2 SMA Batik Surakarta Semester 1 Tahun Pelajaran 2022/2023
Authors: Wibana Ambang
Published: October 2022

Layanan Bimbingan dan Konseling (BK) merupakan bagian integral dari proses pendidikan di satuan pendidikan. Bimbingan dan konseling pada satuan pendidikan mencakup empat bidang layanan, yaitu layanan pengembangan pribadi, sosial, pembelajaran, dan profesional. Tujuan dari pelaksanaan penelitian ini adalah untuk meningkatkan pemahaman proses menuju dunia kerja pada siswa kelas XII-S 2 SMA Batik 1 Surakarta semester 1 Tahun Pelajaran 2022/2023 melalui layanan informasi karir metode Mind Mapping. Penelitian ini adalah Penelitian Tindakan kelas, Subjek penelitian tindakan kelas ini adalah seluruh siswa kelas XII-S 2 SMA Batik 1 Surakarta Tahun Pelajaran 2022/2023 yang berjumlah 43 siswa. Objek penelitian tindakan kelas ini adalah kematangan perencanaan karir, pemahaman proses menuju dunia kerja, dan metode Mind Mapping. Data yang dikumpulkan dalam penelitian ini yaitu data kuantitatif dan data kualitatif. hasil penelitian menunjukkan bahwa melalui layanan informasi karir metode Mind Mapping dapat meningkatkan kematangan perencanaan karir dari kondisi awal. Melalui layanan informasi karir metode Mind Mapping dapat menumbuhkan pemahaman proses menuju dunia kerja.
Perceptions of Tele-orthodontics Application during the COVID-19 Pandemic among University of North Sumatra Dental Student
Authors: Wijayanti Putri Novita
Published: October 2022

Orthodontics is a dentistry specialty that addresses the diagnosis, prevention, management, and correction of mal-positioned teeth and jaws, and misaligned bite patterns which treatment usually takes a long time. Restrictions on direct dental oral health services during the COVID-19 pandemic have encouraged the use of online oral health services via tele-orthodontics over the past few years. This study aimed to investigate tele-orthodontics perceptions among dental students. subjects from various sources of information, not only relying on knowledge in school. A total of 106 dental students who is in their fourth year participated in this cross-sectional descriptive survey. Data were collected using a validated self-reported questionnaire to measure knowledge, beliefs, and attitudes toward tele-orthodontics. It was observed 85.38% of students had knowledge regarding teledentistry, and tele-orthodontics. It showed that as many as 80.37% of University of North Sumatra Dental Student had a positive perception of the tele-orthodontics application during the COVID-19 pandemic. The overall beliefs and attitude of teledentistry were found to be 75.36%. Generally, dental students have positive perception towards tele-orthodontics application during the COVID-19 pandemic.