bluuebunny/crossref_metadata_2025 huggingface dataset:
Precision in Action: The Role of Clustered Regularly Interspaced Short Palindromic Repeats/Cas in Gene Therapies
Authors: Banda Amrutha , Impomeni Olivia , Singh Aparana , Baloch Abdul Rasheed , Hu Wenhui , Jaijyan Dabbu Kumar
Published: June 2024

Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)-associated enzyme-CAS holds great promise for treating many uncured human diseases and illnesses by precisely correcting harmful point mutations and disrupting disease-causing genes. The recent Food and Drug Association (FDA) approval of the first CRISPR-based gene therapy for sickle cell anemia marks the beginning of a new era in gene editing. However, delivering CRISPR specifically into diseased cells in vivo is a significant challenge and an area of intense research. The identification of new CRISPR/Cas variants, particularly ultra-compact CAS systems with robust gene editing activities, paves the way for the low-capacity delivery vectors to be used in gene therapies. CRISPR/Cas technology has evolved beyond editing DNA to cover a wide spectrum of functionalities, including RNA targeting, disease diagnosis, transcriptional/epigenetic regulation, chromatin imaging, high-throughput screening, and new disease modeling. CRISPR/Cas can be used to engineer B-cells to produce potent antibodies for more effective vaccines and enhance CAR T-cells for the more precise and efficient targeting of tumor cells. However, CRISPR/Cas technology has challenges, including off-target effects, toxicity, immune responses, and inadequate tissue-specific delivery. Overcoming these challenges necessitates the development of a more effective and specific CRISPR/Cas delivery system. This entails strategically utilizing specific gRNAs in conjunction with robust CRISPR/Cas variants to mitigate off-target effects. This review seeks to delve into the intricacies of the CRISPR/Cas mechanism, explore progress in gene therapies, evaluate gene delivery systems, highlight limitations, outline necessary precautions, and scrutinize the ethical considerations associated with its application.
West Nile Virus Seroprevalence in Wild Birds and Equines in Madrid Province, Spain
Authors: Williams Richard A. J. , Criollo Valencia Hillary A. , López Márquez Irene , González González Fernando , Llorente Francisco , Jiménez-Clavero Miguel Ángel , Busquets Núria , Mateo Barrientos Marta , Ortiz-Díez Gustavo , Ayllón Santiago Tania
Published: June 2024

West Nile virus (WNV) is a re-emerging flavivirus, primarily circulating among avian hosts and mosquito vectors, causing periodic outbreaks in humans and horses, often leading to neuroinvasive disease and mortality. Spain has reported several outbreaks, most notably in 2020 with seventy-seven human cases and eight fatalities. WNV has been serologically detected in horses in the Community of Madrid, but to our knowledge, it has never been reported from wild birds in this region. To estimate the seroprevalence of WNV in wild birds and horses in the Community of Madrid, 159 wild birds at a wildlife rescue center and 25 privately owned equines were sampled. Serum from thirteen birds (8.2%) and one equine (4.0%) tested positive with a WNV competitive enzyme-linked immunosorbent assay (cELISA) designed for WNV antibody detection but sensitive to cross-reacting antibodies to other flaviviruses. Virus-neutralization test (VNT) confirmed WNV antibodies in four bird samples (2.5%), and antibodies to undetermined flavivirus in four additional samples. One equine sample (4.0%) tested positive for WNV by VNT, although this horse previously resided in a WN-endemic area. ELISA-positive birds included both migratory and resident species, juveniles and adults. Two seropositive juvenile birds suggest local flavivirus transmission within the Community of Madrid, while WNV seropositive adult birds may have been infected outside Madrid. The potential circulation of flaviviruses, including WNV, in birds in the Madrid Community raises concerns, although further surveillance of mosquitoes, wild birds, and horses in Madrid is necessary to establish the extent of transmission and the principal species involved.
Divergent Immune Responses to Minor Bovine Mastitis-Causing Pathogens
Authors: Srithanasuwan Anyaphat , Pangprasit Noppason , Mektrirat Raktham , Suriyasathaporn Witaya , Chuammitri Phongsakorn
Published: June 2024

Traditionally, non-aureus staphylococci and mammaliicocci (NASM) were not considered significant players in bovine mastitis. This study investigated the involvement of NASM (Staphylococcus hominis and Staphylococcus chromogenes) and lactic acid bacteria (LAB) strains (Weissella paramesenteroides) through bovine neutrophil responses. Bovine neutrophils displayed minimal apoptosis upon NASM and LAB challenge. Neutrophils expressed high TLR2 after challenge, but TLR6 expression varied and remained low in NASM pathogen recognition. Bovine neutrophils effectively engulfed and killed LAB, but their activity was significantly impaired against NASM. This was evident in S. chromogenes, where reduced TLR6 recognition and a weakened phagocytic response likely contributed to a lower bactericidal effect. Regardless of the bacteria encountered, intracellular ROS production remained high. S. chromogenes-challenged neutrophils displayed upregulation in genes for pathogen recognition (TLRs), ROS production, and both pro- and anti-apoptotic pathways. This response mirrored that of Weissella. except for CASP9 and BCL2, suggesting these bacteria have divergent roles in triggering cell death. Our findings suggest that S. chromogenes manipulates bovine neutrophil defenses through coordinated changes in functional responses and gene expression, while LAB strains have a weaker influence on apoptosis.
Hydrochemistry and Stable Isotopes for the Investigation of Water Movement in Bioretention Column Experiments
Authors: Yang Yifan , Zhang Xiang , Wang Chao , Chen Lei , Cai Jinhan , Wang Jingyi
Published: June 2024

Bioretention can be an efficient measure of stormwater treatment. The bioretention system has been globally adapted for controlling rainfall-runoff volume and removing pollutants. However, there is a lack of systematic analysis of some hydrological processes in the bioretention facility, such as the transportation of rainfall-runoff (event water) and soil water (pre-event water). This research uniquely applied stable isotope tracing to a bioretention system to investigate the transport of rainfall-runoff and the movement of soil water in a bioretention column. The stable isotope tracing method is helpful for determining the transport process of water and is expected to enhance our understanding of bioretention systems. The ratio of the event rainfall-runoff and the pre-event soil water in the bottom outflow of bioretention columns was calculated by the stable isotope bivariate mixing model based on the oxygen and hydrogen stable isotopic data from continuous testing in the discharge of bioretention column. The time-varying proportion of event water and pre-event water in the hydrographic curve reveals that the outflow process of soil water is divided into three stages. In the early stage, all the outflow was soil water, accounting for about 6–13% of the total outflow. In the middle stage, the proportion of soil water rapidly decreased from 100% to 20% within a few minutes. In the later stage, the soil water proportion decreased slowly from 20% to 0%. The outflow of soil water accounted for more than 36% of the total outflow and decreased with the extension of the drought period. Soil water is a critical part of the bottom outflow of bioretention columns, and the influence of soil water on the hydrological effect of bioretention columns cannot be ignored.
Employing Tank Constraints to Present Total Cost and Water Age Trade-Offs in Optimal Operation of Water Distribution Systems
Authors: Shmaya Tomer , Ostfeld Avi
Published: June 2024

Water distribution systems (WDSs) are massive infrastructure systems designed to supply water from sources to consumers. The optimal operation problem of WDSs is the problem of determining pump and tank operation to meet the consumers’ demands with minimal operating cost, under different constraints, which often include hydraulic feasibility, pressure boundaries, and water quality standards. The water quality aspect of WDSs’ operation poses significant challenges due to its complex mathematical nature. Determined by mixing in the systems’ nodes, it is affected by flow directions, which are subject to change based on the hydraulic state of the system and are therefore difficult to either predict, control, or be included in an analytical model used for optimization. Water age, which is defined as the time water travels in the system until reaching the consumer, is often used as a general water quality indicator—high values of water age imply low water quality, whereas low values of water age usually mean fresher, cleaner, and safer water. In this work, we present the effects that tank operation has on water age. As tanks contain large amounts of water for long periods of time, water tends to age there significantly, which translates into older water being supplied to consumers. By constraining the tank operation, we aim to present the trade-off between water age, tank operation, and operational cost in the WDS optimal operation problem and provide an operational tool that could assist system operators to decide how to operate their system, based on their budget and desired water age boundary. The analysis is applied to three case studies that vary in size and complexity, using MATLAB version R2021b and EPANET 2.2. The presented results show an ability to mitigate high water age in water networks through tank constraints, which varies in accordance with the system’s complexity and tank dominance in supply. The importance of a visual tool that serves as a guide for operators to tackle the complex problem of controlling water age is demonstrated as well.
Experimental Study on the Hydraulic Performance of the Horizontal Main Drain of Building Drainage Systems Affected by Surfactants Sodium Dodecyl Benzene Sulfonate and Alkyl Ethoxylate-9
Authors: Hu Shengjie , Xu Ping , Fu Bin
Published: June 2024

Surfactants play a pivotal role in daily life owing to their commendable performance. The outbreak of the COVID-19 pandemic notably escalated surfactant usage. Upon entering building drainage systems with wastewater, surfactants profoundly influence hydraulic performance, an aspect that has garnered limited scholarly attention. This study employs an equally proportioned drainage test device to meticulously examine the variances in physical properties between surfactants, such as sodium dodecyl benzene sulfonate (SDBS) and alkyl ethoxylate-9 (AEO-9), and their repercussions on the hydraulic dynamics of building drainage horizontal main drains. Our findings reveal that the introduction of surfactants leads to the following: (1) an augmentation in water velocity and deposition distances of the solid simulant in the building drainage horizontal main drain with concentrations exacerbating this effect. The deposition distance of the solid simulation surged by up to 527% under experimental conditions compared to no surfactant; (2) there was a suppression of hydraulic jump and full degree of the horizontal main drain, with the concentration amplifying this suppression; and (3) an exacerbation of positive pressure in the horizontal main drain was found with increasing concentration, reaching a staggering 235.3% elevation compared to no surfactant. Moreover, SBDS foam outperformed AEO-9, demonstrating a 17.70–36.04% higher positive pressure in the horizontal main pipes. SBDS exhibits lower starting and ultimate viscosity, along with smaller colloid particle sizes, resulting in a 0.9–2.0% reduction in hydraulic jump and full degree. However, its inferior drag-reduction capability leads to a 17.48–36.44% decrease in the final deposition distances of solid simulant in the building drainage horizontal main drain compared to AEO-9.
The role of the State land use planning register in establishing the boundaries of agricultural lands
Authors:   Land Management Department, State University of Land Use Planning, Moscow, Fedorinov A.V. , Fomkin I.V. ,   Land Management Department, State University of Land Use Planning, Moscow, Svirezhev K.A. ,   Land Management Department, State University of Land Use Planning, Moscow, Sorokin A.A. ,   Department for maintaining normative and reference information of the information and analytical support department of the Federal State Budgetary Institution "Roslesinforg"
Published: June 2024

The article provides a brief analysis of the materials from the State land use planning register obtained in a result of land management activities. The prospects of using these materials for the development of projects for the establishment of boundaries of agricultural lands and the restoration of abandoned agricultural lands are outlined in this paper.
Development of the Arctic zone of the Russian Federation. State program "Arctic hectare"
Authors:   Real Estate and Land Use Cadastre Department, State University of Land Use Planning, Moscow, Katalina L.A.
Published: June 2024

The article provides basic information about the Arctic zone of the Russian Federation, and about development and features of the implementation of the State Program “Arctic Hectare”.
Criterios para la valoración de prueba pericial médico legista como garantía al debido proceso
Authors: Reina Bravo Mariuxi Patricia , Zambrano López Narcisa Del Urbe , Martínez Pérez Odette
Published: June 2024

Los criterios de valoración de la prueba pericial médico-legal son los lineamientos que deben guiar a los jueces para analizar y otorgar el valor probatorio adecuado a los dictámenes periciales presentados en un proceso judicial. El objetivo de este artículo es describir los criterios de valoración de prueba pericial médico legista como garantía al debido proceso. Se desarrolló bajo el enfoque cualitativo, el paradigma fue interpretativo y el método hermenéutico. El diseño fue documental La técnica para recopilar la información se utilizaron las revistas Scielo, Readic, Scorpus, así mismo se analizó la Constitución de la República del Ecuador, el Código Penal de Ecuador y los textos legales de la medicina. Los resultados desde el enfoque doctrinal en la prueba pericial médico legista se caracteriza por el rol e imparcialidad del perito médico-legista, donde el perito médico-legista cumple un papel esencial al aportar información técnica y científica relevante. Se concluye que, estos enfoques facilitan la interpretación y aplicación de la prueba pericial, asegurando su efectividad como herramienta para la toma de decisiones judiciales.
La conciliación como presupuesto para la materialización del principio de mínima intervención penal en Ecuador
Authors: Ramiro Tigua Raúl , Pérez Cobo Gyomar Beatriz
Published: June 2024

En el contexto del sistema penal ecuatoriano, el principio de mínima intervención penal emerge como un pilar fundamental para garantizar el equilibrio entre la tutela de bienes jurídicos y el respeto a los derechos y libertades individuales. El objetivo del estudio es comprender la conciliación como presupuesto para la materialización del principio de mínima intervención penal en Ecuador. El enfoque es cualitativo, paradigma interpretativo, Orientado en el método fenomenológico-hermenéutico, de tipo dogmático-jurídica. Los resultados revelan el principio de mínima intervención penal se erige como un faro que guía hacia un sistema de justicia penal más justo, humano y eficaz, su objetivo es evitar la criminalización innecesaria y fomentar la resolución de conflictos de manera satisfactoria para todas las partes involucradas. En conclusión, se ha comprendido la importancia de la conciliación y otros mecanismos alternativos a la justicia convencional como herramientas para transformar el sistema penal hacia un enfoque más justo, efectivo y restaurativo
EFFECTIVENESS OF NIPPLE STIMULATION ON LABOR PROGRESS : EVIDENCE BASED CARE REPORT
Authors: Ayu Nurjannah Triastika , Ulfah Kurniaty , Sriyanti Chris
Published: June 2024

Introduction: Prolonged labor is labor that lasts more than 24 hours for primigravida and or 18 hours for multigravida. Prolonged labor is one of several causes of maternal and newborn mortality. As labor progresses, contractions become more frequent, longer and stronger in intensity. Adequate contractions are needed so that labor can take place normally. Nipple stimulation is one way that can be used in increasing uterine contractions. Nipple stimulation causes the breasts to become aroused which causes the intensity of uterine contractions due to the stimulation of the receptors to loosen. This action can be stopped if the contractions experienced have become strong and prolonged. This method is a cost beneficial and effective alternative to induction and augmentation of labor.
Objectives:To evaluate effectiveness of nipple stimulation on labor
Method: Electronic database literature searches, namely Pubmed and Google Scholar.
Result:  Two articles were selected from the literature search and then critically reviewed. Based on the study of Gulbahtiyar Demirel and Hanan Ibrahim et al, it was found that nipple stimulation is effective in reducing the induction of elective labor and there is an effect of nipple stimulation on the progress of labor in laboring women.
Conclusion: In this case, nipple stimulation was effective on the progress of labor in laboring mothers.
PENANGANAN SAMPAH DI TEMPAT WISATA PANTAI X TAHUN 2023
Authors: Puspita Lista , Karmini Mimin
Published: June 2024

Pantai X merupakan salah satu tempat wisata yang banyak diminati. Kegiatan wisata selain bisa bernilai ekomoni juga bisa menjadi penghasil sampah. Oleh karena itu, perlu penanganan yang baik agar tidak menimbulkan dampak buruk terutama untuk lingkungan dan kesehatan. Tujuan penelitian yaitu mengetahui timbulan sampah, tingkat pengetahuan pedagang dan petugas kebersihan, penanganan sampah tahap pemilahan, pewadahan, pengumpulan, pengangkutan, sarana prasarana dan pengurangan sampah dengan prinsip 3R. Populasinya seluruh pedagang berjumlah 30 orang dan petugas kebersihan 5 orang. Sampel pedagang dan petugas kebersihan diambil secara keseluruhan.Teknik pengumpulan data dengan cara penimbangan, wawancara dan observasi. Alat pengumpul data timbangan, kuesioner, lembar observasi, kamera. Analisa data univariat. Timbulan sampah selama 8 hari berturut-turut sebanyak 196.8 Kg/hari  dengan rata-rata 24.6 Kg/hari, Tingkat pengetahuan pedagang 40% kategori baik, petugas kebersihan 100% baik. Tahap pemilahan sampah 100% tidak memenuhi syarat. Tahap pewadahan oleh pedagang 90% memenuhi syarat dan oleh petugas kebersihan 100% tidak memenuhi syarat. Tahap pengumpulan sampah 100%  tidak memenuhi syarat. Tahap pengangkutan sampah 100% tidak memenuhi syarat. Sarana dan prasarana 100% tidak memenuhi syarat. Melakukan reduksi sampah dari sumbernya dengan membuat bank sampah untuk mendapatkan sampah yang bernilai ekonomis.
Analysis of Language Acquisition in Children Aged 0-5 Years in the Care of Career Mother: Behaviorism Theory-B.F Skinner
Authors: Napitupulu Lilis Handayani , Bako Evi Novalin
Published: June 2024

This research aims to reveal the language acquisition of children aged 0-5 years old in career-mother’s parenting by using behaviorism theory by B.F Skinner that is language acquisition formed by associative relationship between stimulus and repetitive responses to form reinforcement (habits). The influence of a career mother requires a child to be left at home with a babysitter, so it affects to the language acquisition of the child. This research uses qualitative method with the subject of research is five childrens aged 0-5 years old who the mothers are a ful-time worker and raised by a different babysitter substantially in language teaching for the children. The method that is used in this research is descriptive qualitative method. Directly observation and interview technique are used as data analysis technique. The result of the analysis shows that the pattern of children’s parenting is very influential on the language acquisition. The interaction between a mother and a child or a babysitter and a child is a form of stimulus to the children and repeated responses so that the reinforcement will determine the success of children’s language acquisition. Environtment plays a significant role in language development especially in vocabulary. Therefore, the children need to be involved in a dialogue or conversation, a question and interactive language.
Comportamiento del consumidor de Internet en las etapas de las compras en línea
Authors: Tinh Nguyen Huu , Banka Michal Sebastian , Tien Nguyen Hoang , Trai Doan Van
Published: June 2024

Las compras online no pueden considerarse una tendencia emergente porque se han convertido en una forma estándar de hacer negocios. El interés de los minoristas online debe centrarse en el comportamiento del cliente durante el proceso de compra. El objetivo de este trabajo es describir y analizar el uso de Internet en la etapa de precompra de los clientes en países seleccionados. Encontramos que existe una correlación negativa significativa entre los indicadores de desarrollo de las naciones y el uso de Internet en la etapa previa a la compra de compras. Además, existe una diferencia significativa entre los consumidores europeos y asiáticos que utilizan Internet durante la etapa previa a la compra en varias actividades observadas.
Filistin’de Finansal Gelişme - Ekonomik Büyüme İlişkisi
Authors: Arslan Erdal
Published: June 2024

Ekonomik literatürdeki finansal gelişme ile ekonomik büyüme arasındaki ilişki, finansal sistemin bir ülkeden diğerine farklılık göstermesi sebebiyle, her ülke için farklı büyüme oranlarına ve ekonomik gelişmeye yol açabilmektedir. Bu çalışmada, 2007:Q1-2020:Q1 zaman serisi verilerine dayanarak, otoregresif dağıtılmış zaman aralığı (ARDL) modelini kullanarak Filistin'deki finansal gelişme, ekonomik büyüme ve kısa vadeli finansal kalkınma dinamikleri arasında uzun vadeli denge bağlantılarının bulunması amaçlanmaktadır. Çalışma sonucunda, finansal derinlik endeksi (M2/RGDP) ile reel GSYH (Gayri Safi Yurt İçi Hasıla) tarafından temsil edilen ekonomik büyüme arasında uzun vadeli negatif bir ilişki olduğunu ve sonuçların uzun vadede Filistin'deki finansal gelişme ile ekonomik büyüme arasında ortak bir tamamlayıcılık gösterdiği ortaya konmaktadır.
II. Abdülhamid Döneminde Kudüs’te Alman Hıristiyan Hacılar için Kurulan Müesseseler
Authors: Gölpınar Asuman
Published: June 2024

Kudüs, günümüzde olduğu gibi tarih boyunca da Hıristiyanlar için en özel hac mekânı olmuştur. Özellikle 19. yüzyılın ikinci yarısı itibarıyla devrin emperyalist güçlerinin kendi aralarındaki artan rekabeti, Kudüs’e de “dini rekabet” görüntüsüyle yansımış ve bu rekabetin bir unsuru da bu şehre gelen Hıristiyan hacılar olmuştur. Almanlar bu sürece daha sonra katılmış olsalar da özellikle II. Abdülhamid döneminde Osmanlı Devleti ile kurdukları iyi ilişkiler neticesinde Kudüs’te, diğer dinî ve hayrî yapıların yanı sıra, hem Katolik hem de Protestan hacıları için oldukça önemli yapılar ve kurumlar inşa ederek bu rekabette öne çıkmışlardır. Bu makalede, devrin atmosferi kısaca özetlendikten sonra Osmanlı arşiv belgelerinden hareketle Alman hacılar ve onlar için yapılan müesseseler ele alınacaktır. Alman Katoliklerin inşa ettiği Dormisyon ve misafirhanesinin izin ve inşa süreçleri belgelerde anlatıldığı şekliyle aktarılmaya çalışılmıştır. Alman Protestanlar da diğer bir başlık olup, burada da ilk Alman Protestan misafirhanesi, Alman imparatoriçesi olan Augusta Victoria’nın adına Zeytin Dağı’nda inşa edilen kilise ve misafirhane mevzu bahis edilmiştir. Nihayetinde, Kudüs’ün siluetine bir “Alman” vurgusuyla damgasını vuran bu yapılar, Osmanlı Devleti ile olan iyi ilişkilerin önemli tezahürlerinden olmuştur. Diğer devlet/cemaatlerin, bu tür müessese inşalarındaki süreçleriyle kıyaslandığında, Almanlarınki oldukça farklı görünmektedir. Almanlar tüm yapmak istedikleri müesseseleri en üst mercilerin izin ve onayıyla yaparak, Osmanlı yasal zemininde hızla ilerlemişler ve Zeytin Dağı ve Cebel-i Sahyun gibi Kudüs’ün en önemli tepelerinde varlıklarını göstererek, bu şehirdeki Hıristiyan dünyanın rekabetinde önemli bir yer edinmişlerdir.
ANALISIS SISTEM INFORMASI MANAJEMEN DALAM PENYALURAN KREDIT USAHA RAKYAT (KUR) PADA PT. BANK RAKYAT INDONESIA (PERSEROAN) TBK. UNIT SUMBAWA BESAR
Authors: SUHANDARI HELDA , BAMBANG BAMBANG , NURABIAH NURABIAH
Published: June 2024

This research aims to analyze the management information system in KUR distribution at Bank Rakyat Indonesia Sumbawa Besar unit. The research method used was a qualitative descriptive approach with data collection techniques through interviews. The informants in this research were the head of the KUR section and staff at the Bank Rakyat Indonesia Sumbawa Besar Unit. The results of this research can be concluded that the use of management information systems in KUR distribution at BRI bank is based on several indicators, namely 1). Accuracy with a high level of truth so that the implementation of management information systems can reduce risks and obstacles when carrying out the data validation process 2). Information is also timely to convey information according to target 3). The information is also in accordance with what is provided to ensure that the information presented is in accordance with consumer needs and finally 4). Information must be complete because it will provide effective support for management in managing the organization efficiently and effectively which will have an impact on their attitude of acceptance of the technology and will have a huge impact on employee performance as well as updates or additions to features in the system that allow users to access information. additional or more detailed and ensure that the information presented by the system can be interpreted easily and is used effectively to design mechanisms or features in the KUR management information system in a format that is easy to understand
PENGARUH INDEKS PEMBANGUNAN MANUSIA DAN KEPADATAN PENDUDUK TERHADAP INDEKS KUALITAS LINGKUNGAN HIDUP DI PULAU JAWA TAHUN 2012-2021
Authors: AULIA RIZKA ELFINA , BUDI AGUNG SETIA , PUJIATI AMIN
Published: June 2024

The decline in environmental quality will be influenced by non-human influences and human influences. Increasing environmental aspects is inversely proportional to improving economic aspects. This research uses fixed model analysis techniques to see how human development and population density have an impact on the quality of the environment on the island of Java from 2012-2021. Calculations in this research state that the human development index has a significantly positive impact on environmental quality, while population density itself has a positive and insignificant impact on the environmental quality index.
PROSES PERJANJIAN BAGI HASIL ATAS TANAH PERTANIAN DI DESA LIMEHE BARAT KECAMATAN TABONGO KABUPATEN GORONTALO
Authors: MAHMUD SILVANA ADELIYA , THALIB MUTIA CHERAWATY , ABDUSSAMAD ZAMRONI , KADIR MUHAMAD KHAIRUN KURNIAWAN , MAMU KARLIN Z.
Published: June 2024

A production sharing agreement is one of the transactions for cultivating agricultural land. This agreement is based on the basis of mutual assistance and a feeling of kinship which is still very strong among the people whose implementation is still not in accordance with existing provisions. This research aims to find out how the agricultural land production sharing agreement process is in West Limehe Village, Kec. Tabongo, Gorontalo Regency. The approach that has been implemented in scientific research is the Sociological Research Approach, which actually progresses the study of science in an expert way by directly exploring its objects. The research results show that the implementation of production sharing agreements on agricultural land in West Limehe Village, Kec. Tabongo, Gorontalo Regency was made unwritten only in verbal form on the basis of trust and agreement between the land owner and the cultivator, it was not carried out in front of the Village Head and no written deed or contract was made from this legal act
ANALISIS PENGUKURAN KINERJA KEUANGAN BERDASARKAN RASIO PROFITABILITAS PADA PT. ASTRA AGRO LESTARI, TBK
Authors: SUMISUSILAWATI SUMISUSILAWATI , NURHAYATI NURHAYATI
Published: June 2024

This study is to determine the financial performance of PT Astra Agro Lestari, Tbk in terms of profitability ratios for the period 2013-2022. The type of research used in this research is descriptive quantitative. This research was conducted to determine and analyze the profitability ratio to assess the financial performance of PT Astra Agro Lestari, Tbk. In measuring the company's financial performance. The data analysis technique used is the profitability ratio which includes Net Profit Margin (NPM), Return On Asset (ROA), Return On Equity (ROE). By using the one sample T-test test with the help of SPSS Version 22. The sample used is purposive sampling with certain sampling with available data for the last 10 years, namely from 2013-2022. The results of the analysis show that the financial performance of Net Profit Margin (NPM) the company's financial performance is in the very good category because it is above the average standard of the company's industry and for Return On Asset (ROA) and Return On Equity (ROE) the company's financial performance is in the poor category because it is below the average standard of the company's industry
TUNTUTAN PIDANA DALAM PENYELESAIAN SENGKETA PERJANJIAN DI INDONESIA
Authors: UMAMI ALLAN MUSTAFA , SATRIAWAN HERA ALVINA
Published: June 2024

Agreement disputes in Indonesia occur due to non-fulfillment of the rights of one party in the agreement by the other party. The agreement is made to serve as strong evidence if a dispute arises in the future. An agreement is a material law that applies to the parties who make it in accordance with the principle of pacta sunt servanda in Article 1338 of the Civil Code (KUHPer). The nature of this material law regulates the parties, but formal law is needed which aims to enforce this material law, which is also known as procedural law. In the event that an agreement is not fulfilled and a dispute arises, it can be caused by a breach of contract, an unlawful act, a defect in the will known in the Civil Code which is resolved through formal civil law mechanisms. It is possible that other legal remedies could be taken by the injured party, namely through a formal criminal law approach. The criminal settlement approach is used with the intention that the party who is charged or sued immediately completes his obligations. Of course, criminal efforts cannot immediately interfere in civil cases without there being evidence that there is a criminal element or a legal basis for the dispute to be directed to criminal prosecution. The formulation of the problem in this research is what is the law of criminal prosecution in resolving contractual disputes in Indonesia? The purpose of this research is to determine the law of criminal prosecution in resolving contractual disputes in Indonesia. The research method used in this research is normative legal research. The results of the research state that criminal charges to resolve agreement disputes are very possible provided that one of the parties has been proven to have committed a criminal act in the pre-agreement, agreement and post-agreement stages and with the proven criminal act being the basis for the aggrieved party to add to the claim for an unlawful act. regulated in Article 1365 of the Civil Code
PRAKTIK PENYELESAIAN SENGKETA PERTANAHAN SECARA LITIGASI
Authors: RISDIANA RISDIANA
Published: June 2024

Article 33 paragraph (3) of the 1945 Constitution, which states that: "Earth and water and the wealth contained therein are controlled by the State and used for the greatest prosperity of the people." Epistemologically, this shows that there are at least two main things relating to the relationship between the State, the people and the region (agrarian). The agrarian problem starts from the very prominent inequality in land tenure structures. The control structure in this case is the distribution or distribution arrangement, both regarding ownership and control over agrarian resources, including the distribution of allocation or allocation. Many agrarian conflicts occur between communities, many land conflicts that occur within communities are resolved through mediation both at the village level and at the regional level with the existence of mediation halls that have been prepared by the government of each region, but if a deliberative settlement does not meet the results then the final step is The solution taken is settlement through litigation. Litigation is used by the community, bringing it to court (in the form of a dispute), to implement/enforce a certain right, through a judicial process (competition of evidence), to obtain a favorable decision
STUDI PUTUSAN KASUS ANGGOTA POLRI PELAKU PENELANTARAN ANAK DALAM RUMAH TANGGA
Authors: ASHADY SUHEFLIHUSNAINI , DUDY ARYADI ALMAU
Published: June 2024

This research was conducted to examine the accountability of a member of the Indonesian National Police who neglected a child in the household based on the Kupang district court decision Number 53/Pid.Sus/2019/PN. Kpg. In this case, there was a dissenting opinion from the judge who decided the case. This research is normative legal research so the approaches used are the statutory approach, conceptual approach and case approach. The results of the research show that the judge in his decision used law number 23 of 2004 concerning the elimination of domestic violence to judge child neglect committed by the perpetrator. The judge also continued to consider the perpetrator's profession as an aggravating element. Apart from that, judges not only prioritize aspects of legal certainty, but also aspects of justice and legal benefits. The judge handed down a lower sentence than the prosecutor's request because the judge during the trial discovered the fact that the victim also contributed to the mistake so that the victim and her child were abandoned by the perpetrator. In this case, the victim left the perpetrator's residence, even though he was not divorced
PENGGUNAAN KANTONG KAIN (TOTE BAGS) PENGGANTI KANTONG PLASTIK PADA REMAJA KOTA DENPASAR
Authors: WIDYASARI NI LUH , WEDAYANI NI MADE , GITAYANI NI NYOMAN TRI
Published: June 2024

The phenomenon of reducing the use of plastic bags is an important concern that still continues to be socialized nowadays since it is related to the issue of sustainable environmental pollution. In relation to that phenomenon, this study focused on the existence of tote bags as the substitute of plastic bags that are used by people while doing shopping. It aims to analyze the enthusiasm of teenagers in using the tote bag as the action to decrease the plastic usage in the environment. The data of this study were collected by fulfilling the questionnaire which involved 100 teenagers in the Denpasar City as respondents. The findings of this study indicate that the awareness, understanding, and influence of the social environment are important factors for Denpasar City teenagers in implementing plastic bag diet behavior. As many as 36% of teenagers in Denpasar City rarely receive plastic bags when shopping, and 53% of the respondents always provide tote bags as a substitute for plastic bags when do shopping. Based on the result of the likert scale, the data shows the effectiveness of the regulation in reducing the use of plastic bags in Denpasar City can be categorized as the effective ones
KARAKTERISTIK PENYIMPANAN LENGAS TANAH OPTIMUM PADA SISTEM JARINGAN IRIGASI TETES PIPA PVC DENGAN EMITTER 4LT/JAM
Authors: NEGARA I DEWA GEDE JAYA , SUPRIYADI ANID , AGASTYA DEWANDHA MAS , SULISTIYONO HERI , YASA I WAYAN
Published: June 2024

Soil moisture is the most important part of irrigation activities, because it is the result achieved by providing irrigation on a particular land. Likewise, with the application of drip irrigation, soil moisture is also the purpose of irrigation in the planting medium. In multilevel drip irrigation sistems, the potential for soil moisture produced by the irrigation sistem is very important to pay attention to, because the size of the moisture that can be provided will affect the scheduling of the drip irrigation provided. And therefore the ability of an irrigation sistem to provide optimum soil moisture in a particular medium deserves attention, before the sistem is applied to farming activities. For this reason, this test aims to determine the ability to provide soil moisture in a drip irrigation sistem that uses a 4 liter/hour emitter in a 4-tiered drip irrigation network, a polybag planting medium and an irrigation duration of 5 minutes to 20 minutes. The test data analyzed is irrigation and soil moisture distribution data, then the results of the analysis are presented in tabular form and discussed and conclusions are drawn. The test results show that the distribution of drip irrigation water occurs evenly with the optimal application of 41% moisture, and with the application of additional soil moisture of around 6% -7% for an irrigation duration of 20 minutes. The daily decrease in soil moisture that occurred during the three days of testing was found to be around 2% as a result of evaporation
MANAJEMEN PEMBELAJARAN BAHASA ARAB UNTUK MENINGKATKAN MOTIVASI BELAJAR SISWA DI MADRASAH ALIYAH AL-AZIZIYAH PUTRA GUNUNG SARI
Authors: IZOMI M. SYAHRUL
Published: June 2024

The aim of this research is to find out the management of Arabic language learning at Al-aziziyah high school son of Gunung Sari, to find out how students' learning motivation is in learning Arabic at Al-aziziyah high school son of Gunung Sari. The Research Method used is field research with a qualitative approach whose research (field research) is qualitative, therefore the journal that the author compiled uses a qualitative descriptive approach. Based on the results of the study, it shows that the management of Arabic language learning in Madrasah Aliyah Al-aziziyah putra Gunung sari is not optimal. Student learning motivation in Arabic language learning at Al-aziziyah high school  putra Gunung sari and have not been motivated in learning Arabic even though thoroughly, judging from the learning process of students in the classroom students listen to the teacher who is explaining in front of the class, there is still less motivation to learn Arabic for students in the Al-aziziyah high school putra Gunung sari.
GAMBARAN TINGKAT PENGETAHUAN MASYARAKAT TENTANG SWAMEDIKASI OBAT ANALGESIK DI DUSUN PONDOK BUAK
Authors: OKTAVIANI NUR
Published: June 2024

Self-medication is the behavior of self-administering drugs based on a diagnosis of experienced symptoms. As many as 103,860 or 35.2% out of 294,959 households store drugs for self-medication, and the most commonly experienced complaint leading to self-medication is pain. Pain can become a problem if it is not promptly treated, leading to prolonged illness and potential harm to the individual. The aim of this research is to describe the public's knowledge level regarding self-medication of analgesic drugs in Pondok Buak village. This research is quantitative descriptive. This study's sample comprises of 134 people from the community who had self-medicate with analgesic medicines and satisfied the inclusion and exclusion criteria. Purposive sampling was employed for sampling. Furthermore, the instrument used in this study was a questionnaire with 11 questions about the level of knowledge of analgesic drug self-medication, which was classified as good (75%-100%), sufficient (56%-75%), and insufficient (56%). Univariate analysis was used to analyse the data. According to the findings, 55% of respondents had a solid knowledge of self-medication, 19% had an adequate comprehension, and 26% showed an insufficient understanding. Finally, with 74 respondents (55%), the description of the public's awareness level regarding self-medication of analgesic medications in Pondok Buak Hamlet is in the good category
PENGARUH PEMBERIAN LARUTAN NaCl TERHADAP PERTUMBUHAN TANAMAN SELEDRI (APIUM GRAVEOLOENS L.)
Authors: SUKERTA I MADE , SUMANTRA I KETUT , RAMDHOANI RAMDHOANI , SUARSANA R. I WAYAN
Published: June 2024

This research is entitled "The Effect of Giving NaCl Solution on the Growth of Celery Plants (Apium Graveoloens L.)". The purpose of this research is to determine the response to the growth of celery plants with the application of NaCl solution and to determine the appropriate concentration of solution to provide the best response to the growth and yield of celery plants. This research was conducted for three months starting from October 2023 to December 2023. The method used in this research was the Randomized Group Design (RAK) method with six treatments, namely 0 g/1 L salt water treatment (NaCl 0), treatment salt 1.5 g/1 L water (NaCl 1), salt treatment 3 g/1 L water (NaCl 2), salt treatment 4.5 g/1 L water (NaCl 3), salt treatment 6 g/1 L air (NaCl 4), salt treatment 7.5 g/1 L water (NaCl 5) with four repetitions. The results of the research showed that the use of NaCl solution has a very real influence on the parameters of plant height, number of stalks, number of tillers, root length, plant fresh weight and oven dry weight. With other treatments shown by the average number of observation parameters, the highest results were shown in the fifth treatment (NaCl 4), namely the average plant height was 44.30/cm, number of leaves was 47.25/piece, number of stalks was 9, 75/stem, number of tillers 3.00/stem, root length 19.13/cm, total fresh weight of plant 32.25/g, oven dry weight of plant 14.50/g.
NEUROMARKETING Y MODA: UNA REVISIÓN SISTEMÁTICA SOBRE SUS IMPLICACIONES SENSORIALES
Authors: Cristófol- Rodríguez Carmen , Porras- Florido Carolina , Cerdá-Suárez Luis Manuel , Mocchi Beatriz
Published: June 2024

Introduction: Fashion is a sector that at all times appeals to the emotions and feelings of the individual, due to its social implications. In this sense, neuromarketing becomes a very valuable tool to study the different reactions of the public when exposed to it. Different tools applied in neuromarketing reveal how consumers feel when they buy, touch or look at a fashion product with which they relate. Methodology: The present research aims to make a systematic review of publications in academic journals on fashion and neuromarketing, as an integrative tool that allows the compilation of studies on the same topic, in order to establish a state of the art. This review is carried out in the Scopus and WOS databases, in Spanish and English, between 2000 and 2023. The objective is to study the neuromarketing tools that are best suited to this sector and to analyze how they have evolved, been used and integrated over the years. Results: Twenty-three results were found that matched the search, and for each one of them the authors studied the country where the research was carried out, the year of publication, the journal where the research was published, the neuromarketing tool applied, the results obtained, and where the manuscript focuses: on the company, on the consumer, on both or on neither of them. Discussion: Twenty-three results were found, of which only 12 were valid. The main cause of exclusion was the repetition of results in the two databases consulted. In these studies, not only the response of the consumer is observed, but fundamentally the response of the company and its perception. Conclusions: It is concluded that neuromarketing and consumer neuroscience tools, although scarce in the fashion industry, provide relevant and useful information and multidisciplinary groups are proposed to increase the scientific production applied to the case study.
Nutrient Status Of The Soil Layers Of Rice Fields In Taratara Satu District, West Tomohon District Tomohon City
Authors: Kamagi Kamagi , Kumolontang Wiesje Junnieke Nathsuo , Sinolungan Meldi Tieneke Magdalena , Rondonuwu Jenny Jeanette
Published: June 2024

Research in the field aims to determine the nutrient status condition in rice fields' soil layers. The things studied are N, P, K, C-organic, soil pH, and soil texture. The research is a survey method with a composite soil sampling technique at 0, 10, and 20 cm depth. Soil samples were taken at six different rice field points in the Taratara area. The nutrient status of N, P, K, and soil pH were analyzed using the Paddy Soil Test Kit (PUTS). C-organic using the Walkley and black method and for soil texture using the pipette method. The data from the analysis is then arranged in table form and explained descriptively. The research results from the six locations studied showed that: 1). N nutrient status is at low status; 2). P nutrient status is low, medium, and high; 3). K nutrient status is at medium and high status; 4). C – Organic nutrient status is at very low and low status and 5). Soil pH is slightly acidic and 6). Soil texture conditions are in the criteria of loam, silty loam, and silty clay loam.
Keywords: Nutrient Status, Paddy Soil Layers.
Abstrak
Penelitian dilakukan di lapangan bertujuan untuk mengetahui kondisi status hara yang ada di lapisan tanah sawah.  Hal-hal yang diteliti adalah: N, P, K, C-organik, pH tanah dan tekstur tanah.  Metode penelitian adalah metode survei dengan teknik pengambilan sampel tanah perlapisan tanah pada kedalaman 0, 10 dan 20 cm secara komposit. Sampel tanah diambil pada enam titik lahan sawah yang berbeda di wilayah Taratara. Status hara N, P, K dan pH tanah dianalisis menggunakan Perangkat Uji Tanah Sawah (PUTS). C-organik dengan metode Walkley and black dan untuk tekstur tanah dengan metode pipet. Data hasil analisis kemudian disusun dalam bentuk tabel kemudian dijelaskan secara deskriptif. Hasil penelitian dari enam lokasi yang diteliti diperoleh bahwa : 1). Status hara N berada pada status rendah; 2). Status hara P berada pada status rendah, sedang dan tinggi; 3). Status hara K berada pada status sedang dan  tinggi; 4). Status hara C – Organik berada pada status sangat rendah dan rendah dan 5). pH tanah berada pada kondisi agak asam serta 6). Kondisi tekstur tanah berada pada kriteria lempung, lempung berdebu dan lempung liat berdebu.

Kata kunci :  Status Hara, Lapisan Tanah Sawah
Non abbiamo (o non facciamo?) difficoltà a rispondervi!
Authors: Coletti Vittorio
Published: June 2024

Alcuni lettori ci hanno chiesto se nell’espressione fare difficoltà non sia preferibile, nei casi che ci sottopongono, sostituire il verbo con avere.
قوة التحمل النفسي وعلاقته ببعض المهارات النفسية لدى لاعبي كرة السلة
Authors: م. أية هيثم خزعل
Published: June 2024

هدفت دراسة البحث التعرف على العلاقة بين قوه التحمل نفسي وعلاقته ببعض مهارات النفسية لدى لاعبي منتخب كلية بكرة السلة ، واستخدمت الباحثة المنهج الوصفي لملائمة مع البحث، وهنا تركزت مشكلة البحث وجود تفاوت في مستوى المهارات النفسية لديهم اثناء الأداء المهاري ، حيث تم اختيار عينة البحث (16 لاعب) من لاعبي منتخب كلية التربية البدنية وعلوم الرياضة / الجامعة المستنصرية بكرة السلة ، وافترضت الباحثة وجود فروق معنوية بين قوة التحمل وبعض المهارات النفسية لدى لاعبي منتخب كلية كرة السلة ، واظهرت الباحثة الاستنتاج من البحث ان الجانب النفسي عامل مهم لديهم جدا في أداء المهارات كرة السلة وجود علاقة ارتباط معنوية بين قوة التحمل النفسي والدافعية وثقة بالنفس والقلق المنافسة الرياضية لدى افراد عينة البحث ، واوصت الباحثة على تقليل الصعوبات النفسية ومحاولة تخفيف حدتها وازالتها عن طريق الأداء الجيد الرياضي والتركيز على التدريب النفسي والبدني خلال تدريباتهم من اجل الوصول الى اعلى أداء في المنافسة.