bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Table 1 from Inhibitors Targeting Mitosis: Tales of How Great Drugs against a Promising Target Were Brought Down by a Flawed Rationale
Authors: Komlodi-Pasztor Edina , Sackett Dan L. , Fojo Antonio Tito
Published: April 2023

PDF file, 91KB, Polo-like Kinase Inhibitors in Clinical Trials.
Supplementary Figure 1 from Ras-Driven Transcriptome Analysis Identifies Aurora Kinase A as a Potential Malignant Peripheral Nerve Sheath Tumor Therapeutic Target
Authors: Patel Ami V. , Eaves David , Jessen Walter J. , Rizvi Tilat A. , Ecsedy Jeffrey A. , Qian Mark G. , Aronow Bruce J. , Perentesis John P. , Serra Eduard , Cripe Timothy P. , Miller Shyra J. , Ratner Nancy
Published: April 2023

XLS file, 636K, 339 Ras-Driven Genes Differentially Expressed in Mouse or Human Neurofibromas or MPNSTs.
Supplementary Table 1 from Functional Profiling of Receptor Tyrosine Kinases and Downstream Signaling in Human Chondrosarcomas Identifies Pathways for Rational Targeted Therapy
Authors: Zhang Yi-Xiang , van Oosterwijk Jolieke G. , Sicinska Ewa , Moss Samuel , Remillard Stephen P. , van Wezel Tom , Bühnemann Claudia , Hassan Andrew B. , Demetri George D. , Bovée Judith V.M.G. , Wagner Andrew J.
Published: April 2023

Supplementary Table 1 - XLS file 48K, Oligos for gene mutation detection
Supplementary Figure 5 from Functional Profiling of Receptor Tyrosine Kinases and Downstream Signaling in Human Chondrosarcomas Identifies Pathways for Rational Targeted Therapy
Authors: Zhang Yi-Xiang , van Oosterwijk Jolieke G. , Sicinska Ewa , Moss Samuel , Remillard Stephen P. , van Wezel Tom , Bühnemann Claudia , Hassan Andrew B. , Demetri George D. , Bovée Judith V.M.G. , Wagner Andrew J.
Published: April 2023

Supplementary Figure 5 - PDF file 324K, Feedback effects on phosphorylation of RTKs following 24 hr treatment of BEZ235 in chondrosarcoma cells
Supplementary Figure 4 from Functional Profiling of Receptor Tyrosine Kinases and Downstream Signaling in Human Chondrosarcomas Identifies Pathways for Rational Targeted Therapy
Authors: Zhang Yi-Xiang , van Oosterwijk Jolieke G. , Sicinska Ewa , Moss Samuel , Remillard Stephen P. , van Wezel Tom , Bühnemann Claudia , Hassan Andrew B. , Demetri George D. , Bovée Judith V.M.G. , Wagner Andrew J.
Published: April 2023

Supplementary Figure 4 - PDF file 240K, Time-dependent effects of PI3K/mTOR pathway inhibitors on the activation of AKT and MAPK signaling pathways
Supplementary Figure 3 from Functional Profiling of Receptor Tyrosine Kinases and Downstream Signaling in Human Chondrosarcomas Identifies Pathways for Rational Targeted Therapy
Authors: Zhang Yi-Xiang , van Oosterwijk Jolieke G. , Sicinska Ewa , Moss Samuel , Remillard Stephen P. , van Wezel Tom , Bühnemann Claudia , Hassan Andrew B. , Demetri George D. , Bovée Judith V.M.G. , Wagner Andrew J.
Published: April 2023

Supplementary Figure 3 - PDF file 230K, Effects of PI3K/mTOR pathway inhibitor in chondrosarcoma cells
Supplementary Figure 4 from Use of [11C]Choline PET-CT as a Noninvasive Method for Detecting Pelvic Lymph Node Status from Prostate Cancer and Relationship with Choline Kinase Expression
Authors: Contractor Kaiyumars , Challapalli Amarnath , Barwick Tara , Winkler Mathias , Hellawell Giles , Hazell Steve , Tomasi Giampaolo , Al-Nahhas Adil , Mapelli Paola , Kenny Laura M. , Tadrous Paul , Coombes R. Charles , Aboagye Eric O. , Mangar Stephen
Published: April 2023

PDF file - 509K
Supplementary Figure 2 from Use of [11C]Choline PET-CT as a Noninvasive Method for Detecting Pelvic Lymph Node Status from Prostate Cancer and Relationship with Choline Kinase Expression
Authors: Contractor Kaiyumars , Challapalli Amarnath , Barwick Tara , Winkler Mathias , Hellawell Giles , Hazell Steve , Tomasi Giampaolo , Al-Nahhas Adil , Mapelli Paola , Kenny Laura M. , Tadrous Paul , Coombes R. Charles , Aboagye Eric O. , Mangar Stephen
Published: April 2023

PDF file - 126K
Supplementary Methods from Biomarker and Pharmacologic Evaluation of the γ-Secretase Inhibitor PF-03084014 in Breast Cancer Models
Authors: Zhang Cathy C. , Pavlicek Adam , Zhang Qin , Lira Maruja E. , Painter Cory L. , Yan Zhengming , Zheng Xianxian , Lee Nathan V. , Ozeck Mark , Qiu Ming , Zong Qing , Lappin Patrick B. , Wong Anthony , Rejto Paul A. , Smeal Tod , Christensen James G.
Published: April 2023

PDF file, 208K, Methods for NanoString gene analysis.
Supplementary Table 1 from Antiviral and Antitumor T-cell Immunity in Patients Treated with GM-CSF–Coding Oncolytic Adenovirus
Authors: Kanerva Anna , Nokisalmi Petri , Diaconu Iulia , Koski Anniina , Cerullo Vincenzo , Liikanen Ilkka , Tähtinen Siri , Oksanen Minna , Heiskanen Raita , Pesonen Saila , Joensuu Timo , Alanko Tuomo , Partanen Kaarina , Laasonen Leena , Kairemo Kalevi , Pesonen Sari , Kangasniemi Lotta , Hemminki Akseli
Published: April 2023

PDF file - 71K, Characteristics of patients na�ve to oncolytic adenovirus.
CCR Translation for This Article from Rapid Angiogenesis Onset after Discontinuation of Sunitinib Treatment of Renal Cell Carcinoma Patients
Authors: Griffioen Arjan W. , Mans Laurie A. , de Graaf Annemarie M.A. , Nowak-Sliwinska Patrycja , de Hoog Céline L.M.M. , de Jong Trees A.M. , Vyth-Dreese Florry A. , van Beijnum Judy R. , Bex Axel , Jonasch Eric
Published: April 2023

CCR Translation for This Article from Rapid Angiogenesis Onset after Discontinuation of Sunitinib Treatment of Renal Cell Carcinoma Patients
Supplementary Figure Legend from Development of an Fc-Enhanced Anti–B7-H3 Monoclonal Antibody with Potent Antitumor Activity
Authors: Loo Deryk , Alderson Ralph F. , Chen Francine Z. , Huang Ling , Zhang Wenjun , Gorlatov Sergey , Burke Steve , Ciccarone Valentina , Li Hua , Yang Yinhua , Son Tom , Chen Yan , Easton Ann N. , Li Jonathan C. , Rillema Jill R. , Licea Monica , Fieger Claudia , Liang Tony W. , Mather Jennie P. , Koenig Scott , Stewart Stanford J. , Johnson Syd , Bonvini Ezio , Moore Paul A.
Published: April 2023

PDF file, 78KB.
Supplemental Table 1 from Anticancer Effects of Niclosamide in Human Glioblastoma
Authors: Wieland Anja , Trageser Daniel , Gogolok Sabine , Reinartz Roman , Höfer Heike , Keller Mihaela , Leinhaas Anke , Schelle Ramona , Normann Sabine , Klaas Lil , Waha Andreas , Koch Philipp , Fimmers Rolf , Pietsch Torsten , Yachnis Anthony T. , Pincus David W. , Steindler Dennis A. , Brüstle Oliver , Simon Matthias , Glas Martin , Scheffler Björn
Published: April 2023

Patient data.
CCR Translation for This Article from Influence of Smoking on the Pharmacokinetics and Toxicity Profiles of Taxane Therapy
Authors: de Graan Anne-Joy M. , Loos Walter J. , Friberg Lena E. , Baker Sharyn D. , van der Bol Jessica M. , van Doorn Leni , Wiemer Erik A.C. , van der Holt Bronno , Verweij Jaap , Mathijssen Ron H.J.
Published: April 2023

CCR Translation for This Article from Influence of Smoking on the Pharmacokinetics and Toxicity Profiles of Taxane Therapy
Supplementary Table 4 from Biomarker Discovery in Non–Small Cell Lung Cancer: Integrating Gene Expression Profiling, Meta-analysis, and Tissue Microarray Validation
Authors: Botling Johan , Edlund Karolina , Lohr Miriam , Hellwig Birte , Holmberg Lars , Lambe Mats , Berglund Anders , Ekman Simon , Bergqvist Michael , Pontén Fredrik , König André , Fernandes Oswaldo , Karlsson Mats , Helenius Gisela , Karlsson Christina , Rahnenführer Jörg , Hengstler Jan G , Micke Patrick
Published: April 2023

XLSX file - 24K, Excel file including uni- and multivariate analysis of the top 17 prognostic probe sets
Supplementary Figure 4 from Biomarker Discovery in Non–Small Cell Lung Cancer: Integrating Gene Expression Profiling, Meta-analysis, and Tissue Microarray Validation
Authors: Botling Johan , Edlund Karolina , Lohr Miriam , Hellwig Birte , Holmberg Lars , Lambe Mats , Berglund Anders , Ekman Simon , Bergqvist Michael , Pontén Fredrik , König André , Fernandes Oswaldo , Karlsson Mats , Helenius Gisela , Karlsson Christina , Rahnenführer Jörg , Hengstler Jan G , Micke Patrick
Published: April 2023

PDF file - 39K, Kaplan-Meier suvival plot of stage I adenocarcinoma patients according to protein expression
Supplementary Figure 3 from Biomarker Discovery in Non–Small Cell Lung Cancer: Integrating Gene Expression Profiling, Meta-analysis, and Tissue Microarray Validation
Authors: Botling Johan , Edlund Karolina , Lohr Miriam , Hellwig Birte , Holmberg Lars , Lambe Mats , Berglund Anders , Ekman Simon , Bergqvist Michael , Pontén Fredrik , König André , Fernandes Oswaldo , Karlsson Mats , Helenius Gisela , Karlsson Christina , Rahnenführer Jörg , Hengstler Jan G , Micke Patrick
Published: April 2023

PDF file - 41K, Kaplan-Meier plots of recurrence free survival according CADM1 gene expression
Supplementary Discussion from Biomarker Discovery in Non–Small Cell Lung Cancer: Integrating Gene Expression Profiling, Meta-analysis, and Tissue Microarray Validation
Authors: Botling Johan , Edlund Karolina , Lohr Miriam , Hellwig Birte , Holmberg Lars , Lambe Mats , Berglund Anders , Ekman Simon , Bergqvist Michael , Pontén Fredrik , König André , Fernandes Oswaldo , Karlsson Mats , Helenius Gisela , Karlsson Christina , Rahnenführer Jörg , Hengstler Jan G , Micke Patrick
Published: April 2023

PDF file - 117K, Analysis of the 14 gene sinature risk score of Kratz et al., 2012
Supplementary Table 2 from Phase I Trial of a Glypican-3–Derived Peptide Vaccine for Advanced Hepatocellular Carcinoma: Immunologic Evidence and Potential for Improving Overall Survival
Authors: Sawada Yu , Yoshikawa Toshiaki , Nobuoka Daisuke , Shirakawa Hirofumi , Kuronuma Toshimitsu , Motomura Yutaka , Mizuno Shoichi , Ishii Hiroshi , Nakachi Kohei , Konishi Masaru , Nakagohri Toshio , Takahashi Shinichiro , Gotohda Naoto , Takayama Tadatoshi , Yamao Kenji , Uesaka Katsuhiko , Furuse Junji , Kinoshita Taira , Nakatsura Tetsuya
Published: April 2023

PDF file, 47KB, There was no significant difference in the clinical background of patients with GPC3-specific CTL frequencies ≥ 50 and those with < 50. A peptide dose of greater than 1.0 mg was required for adequate induction of GPC3-specific CTL frequences ≥ 50.
Supplementary Figure 2 from In Vivo Positron Emission Tomography Imaging of Protease Activity by Generation of a Hydrophobic Product from a Noninhibitory Protease Substrate
Authors: Chuang Chih-Hung , Chuang Kuo-Hsiang , Wang Hsin-Ell , Roffler Steve R. , Shiea Jen-taie , Tzou Shey-Cherng , Cheng Ta-Chun , Kao Chien-Han , Wu Shih-Yen , Tseng Wei-Lung , Cheng Chiu-Min , Hou Ming-Feng , Wang Ju-Ming , Cheng Tian-Lu
Published: April 2023

PDF file - 1.9MB
Supplementary Figure 1 from Phase I Dose-Escalation Study of Intravenous Aflibercept in Combination with Docetaxel in Patients with Advanced Solid Tumors
Authors: Isambert Nicolas , Freyer Gilles , Zanetta Sylvie , You Benoît , Fumoleau Pierre , Falandry Claire , Favier Laure , Assadourian Sylvie , Soussan-Lazard Karen , Ziti-Ljajic Samira , Trillet-Lenoir Veronique
Published: April 2023

PDF file - 68K, Individual median of free to VEGF-bound aflibercept Ctrough ratio observed from cycle.
Supplementary Figures 1 - 9 from Biomarker Analyses from a Placebo-Controlled Phase II Study Evaluating Erlotinib ± Onartuzumab in Advanced Non–Small Cell Lung Cancer: MET Expression Levels Are Predictive of Patient Benefit
Authors: Koeppen Hartmut , Yu Wei , Zha Jiping , Pandita Ajay , Penuel Elicia , Rangell Linda , Raja Rajiv , Mohan Sankar , Patel Rajesh , Desai Rupal , Fu Ling , Do An , Parab Vaishali , Xia Xiaoling , Januario Tom , Louie Sharianne G. , Filvaroff Ellen , Shames David S. , Wistuba Ignacio , Lipkind Marina , Huang Jenny , Lazarov Mirella , Ramakrishnan Vanitha , Amler Lukas , Phan See-Chun , Patel Premal , Peterson Amy , Yauch Robert L.
Published: April 2023

Figure S1. Characterization of SP44 specificity; Figure S2. Relationship of IHC intensity with FACS; Figure S3. Relationship of IHC intensity with mRNA; Figure S4. Representative IHC images; Figure S5 and S6. MET IHC H-scores; Figure S7. Relationship of IHC clinical score with MET copy number; Figure S8. Kaplan-Meier curves of OS according to MET copy number; Figure S9. Relationship of plasma HGF with MET Dx positivity.
Supplementary Figure 3 from The Pivotal Role of Integrin β1 in Metastasis of Head and Neck Squamous Cell Carcinoma
Authors: Wang Dongsheng , Müller Susan , Amin A.R.M. Ruhul , Huang Donghai , Su Ling , Hu Zhongliang , Rahman Mohammad Aminur , Nannapaneni Sreenivas , Koenig Lydia , Chen Zhengjia , Tighiouart Mourad , Shin Dong M. , Chen Zhuo G.
Published: April 2023

PDF file, 897K, IHC analyses on xenograft tumor tissues.
Supplementary Table 1 from Novel Role of MDA-9/Syntenin in Regulating Urothelial Cell Proliferation by Modulating EGFR Signaling
Authors: Dasgupta Santanu , Menezes Mitchell E. , Das Swadesh K. , Emdad Luni , Janjic Aleksandar , Bhatia Shilpa , Mukhopadhyay Nitai D. , Shao Chunbo , Sarkar Devanand , Fisher Paul B.
Published: April 2023

PDF file - 133K, Table S1. Clinical characteristics and expression level of MDA-9/Syntenin in primary UCC tumors
Supplementary Tables 1 - 2 from Molecular Testing for Lymph Node Metastases as a Determinant of Colon Cancer Recurrence: Results from a Retrospective Multicenter Study
Authors: Sargent Daniel J. , Shi Qian , Gill Sharlene , Louvet Christophe , Everson Richard B. , Kellner Udo , Clancy Thomas E. , Pipas J. Marc , Resnick Murray B. , Meyers Michael O. , Wu Tsung-Teh , Huntsman David , Validire Pierre , Farooq Umar , Pavey Emily S. , Beaudry Guillaume , Haince Jean-Francois , Fradet Yves
Published: April 2023

PDF file - 90K, Supplementary Table 1: Adjusted Association between LNR Status and Outcomes in Untreated T3N0 Colon Cancer Undergoing Molecular Staging; Supplementary Table 2: Unadjusted and adjusted association between LNR status and TTR, OS, and DFS within pMMR subgroup (N = 262).
Supplementary Methods and Figure Legend from Combination Small Molecule MEK and PI3K Inhibition Enhances Uveal Melanoma Cell Death in a Mutant GNAQ- and GNA11-Dependent Manner
Authors: Khalili Jahan S. , Yu Xiaoxing , Wang Ji , Hayes Brendan C. , Davies Michael A. , Lizee Gregory , Esmaeli Bita , Woodman Scott E.
Published: April 2023

PDF file, 63K.
Supplementary Tables S9-17 from Functional Kinomics Identifies Candidate Therapeutic Targets in Head and Neck Cancer
Authors: Moser Russell , Xu Chang , Kao Michael , Annis James , Lerma Luisa Angelica , Schaupp Christopher M. , Gurley Kay E. , Jang In Sock , Biktasova Asel , Yarbrough Wendell G. , Margolin Adam A. , Grandori Carla , Kemp Christopher J. , Méndez Eduardo
Published: April 2023

Tables S9-17: Table S9. HT RNAi primary validation screen with siRNA pool deconvolution Table S10. Differential analysis of primary validation screen (CTG) N=12 Table S11. Differential analysis of primary validation screen (CTG) N=3 Pooled Table S12. Statistical analysis summary of differential viability (CTG) Table S13. Statistical analysis (absolute viability) of primary validation screen (CTG) Table S14. HT RNAi primary validation screen summary of hits (CTG) Table S15. HT caspase 3/7-dependent apoptosis AUC analysis (Apotox) N=12 Table S16. HT caspase 3/7-dependent apoptosis AUC analysis (Apotox) N=3 pooled Table S17. Statistical analysis summary caspase 3/7 dependent apoptosis (Apotox)
Supplementary Figure 2 from Antibody-Dependent Cell-Mediated Cytotoxicity Overcomes NK Cell Resistance in MLL-Rearranged Leukemia Expressing Inhibitory KIR Ligands but Not Activating Ligands
Authors: Chan Wing Keung , Kung Sutherland May , Li Ying , Zalevsky Jonathan , Schell Sarah , Leung Wing
Published: April 2023

PDF file - 100K, Characterization of luciferase+ mutant SEM cells. The susceptibility of luciferase+ mutant cell-line to ADCC induced by (A) XmAb5574 or (B) lintuzumab was not changed. (C) Determination of linear range of bioluminescence from mice with luciferase+ mutant SEM. 5�106 SEM cells were injected intravenously and then imaged for bioluminescence over time. The regression coefficients are shown for the ventral and dorsal sides of the mice
Supplementary Figure 3 from BRAF Fusions Define a Distinct Molecular Subset of Melanomas with Potential Sensitivity to MEK Inhibition
Authors: Hutchinson Katherine E. , Lipson Doron , Stephens Philip J. , Otto Geoff , Lehmann Brian D. , Lyle Pamela L. , Vnencak-Jones Cindy L. , Ross Jeffrey S. , Pietenpol Jennifer A. , Sosman Jeffrey A. , Puzanov Igor , Miller Vincent A. , Pao William
Published: April 2023

PDF file - 96K, Supplementary Figure S3. Signaling and inhibition of TRIM24-BRAF.
Supplementary Table 2 from The Zinc Finger Gene ZIC2 Has Features of an Oncogene and Its Overexpression Correlates Strongly with the Clinical Course of Epithelial Ovarian Cancer
Authors: Marchini Sergio , Poynor Elizabeth , Barakat Richard R. , Clivio Luca , Cinquini Michela , Fruscio Robert , Porcu Luca , Bussani Cecilia , D’Incalci Maurizio , Erba Eugenio , Romano Michela , Cattoretti Giorgio , Katsaros Dionyssios , Koff Andrew , Luzzatto Lucio
Published: April 2023

PDF file, 62K, A. List of primer pair sequences used for RT-qPCR analysis and respective annealing temperatures. B. List of siRNA sequences used. C. Details of deletion constructs (see Fig. 4A).
Supplementary Figure 1 from The Zinc Finger Gene ZIC2 Has Features of an Oncogene and Its Overexpression Correlates Strongly with the Clinical Course of Epithelial Ovarian Cancer
Authors: Marchini Sergio , Poynor Elizabeth , Barakat Richard R. , Clivio Luca , Cinquini Michela , Fruscio Robert , Porcu Luca , Bussani Cecilia , D’Incalci Maurizio , Erba Eugenio , Romano Michela , Cattoretti Giorgio , Katsaros Dionyssios , Koff Andrew , Luzzatto Lucio
Published: April 2023

PDF file, 198K, Forced over-expression of ZIC2 in NIH-3T3 cells produces increased cell proliferation and knockdown of ZIC2 protein inhibits proliferation of ovarian cancer cell lines.
Supplementary Table 1 from Transcriptional Characterization of a Prospective Series of Primary Plasma Cell Leukemia Revealed Signatures Associated with Tumor Progression and Poorer Outcome
Authors: Todoerti Katia , Agnelli Luca , Fabris Sonia , Lionetti Marta , Tuana Giacomo , Mosca Laura , Lombardi Luigia , Grieco Vitina , Bianchino Gabriella , D'Auria Fiorella , Statuto Teodora , Mazzoccoli Carmela , De Luca Luciana , Petrucci Maria Teresa , Morabito Fortunato , Offidani Massimo , Di Raimondo Francesco , Falcone Antonietta , Omede' Paola , Tassone Pierfrancesco , Boccadoro Mario , Palumbo Antonio , Neri Antonino , Musto Pellegrino
Published: April 2023

PDF file - 59K, Forty-seven genes differentially expressed in t(11;14), t(4;14) and MAF-associated translocations group.
Supplementary Figure 3 from hVps37A Status Affects Prognosis and Cetuximab Sensitivity in Ovarian Cancer
Authors: Wittinger Michael , Vanhara Petr , El-Gazzar Ahmed , Savarese-Brenner Bettina , Pils Dietmar , Anees Mariam , Grunt Thomas W. , Sibilia Maria , Holcmann Martin , Horvat Reinhard , Schemper Michael , Zeillinger Robert , Schöfer Christian , Dolznig Helmut , Horak Peter , Krainer Michael
Published: April 2023

PDF file - 229K
Supplementary Table 1 from Clinical Significance of the Genetic Landscape of Pancreatic Cancer and Implications for Identification of Potential Long-term Survivors
Authors: Yachida Shinichi , White Catherine M. , Naito Yoshiki , Zhong Yi , Brosnan Jacqueline A. , Macgregor-Das Anne M. , Morgan Richard A. , Saunders Tyler , Laheru Daniel A. , Herman Joseph M. , Hruban Ralph H. , Klein Alison P. , Jones Siân , Velculescu Victor , Wolfgang Christopher L. , Iacobuzio-Donahue Christine A.
Published: April 2023

PDF file - 77K, Primers used for amplification and sequencing of pancreatic cancer driver genes
Supplementary Table 4 from Targeted Therapy for BRAFV600E Malignant Astrocytoma
Authors: Nicolaides Theodore P. , Li Huifang , Solomon David A. , Hariono Sujatmi , Hashizume Rintaro , Barkovich Krister , Baker Suzanne J. , Paugh Barbara S. , Jones Chris , Forshew Tim , Hindley Guy F. , Hodgson J. Graeme , Kim Jung-Sik , Rowitch David H. , Weiss William A. , Waldman Todd A. , James C. David
Published: April 2023

PDF file - 49K
Supplementary Table 2 from Targeted Therapy for BRAFV600E Malignant Astrocytoma
Authors: Nicolaides Theodore P. , Li Huifang , Solomon David A. , Hariono Sujatmi , Hashizume Rintaro , Barkovich Krister , Baker Suzanne J. , Paugh Barbara S. , Jones Chris , Forshew Tim , Hindley Guy F. , Hodgson J. Graeme , Kim Jung-Sik , Rowitch David H. , Weiss William A. , Waldman Todd A. , James C. David
Published: April 2023

PDF file - 42K
Supplementary Table 1 from Targeted Therapy for BRAFV600E Malignant Astrocytoma
Authors: Nicolaides Theodore P. , Li Huifang , Solomon David A. , Hariono Sujatmi , Hashizume Rintaro , Barkovich Krister , Baker Suzanne J. , Paugh Barbara S. , Jones Chris , Forshew Tim , Hindley Guy F. , Hodgson J. Graeme , Kim Jung-Sik , Rowitch David H. , Weiss William A. , Waldman Todd A. , James C. David
Published: April 2023

PDF file - 42K
Supplementary Figure 2. from Mutual Regulation between Raf/MEK/ERK Signaling and Y-Box–Binding Protein-1 Promotes Prostate Cancer Progression
Authors: Imada Kenjiro , Shiota Masaki , Kohashi Kenichi , Kuroiwa Kentaro , Song YooHyun , Sugimoto Masaaki , Naito Seiji , Oda Yoshinao
Published: April 2023

Supplementary Figure 2 - Supplementary Figure 2. Densitometric analyses of Figure 2B - PDF file 94K, (A) Protein expression level of p-EGFR, p-Raf-1, p-MEK, p-ERK1, p-ERK2, p-RSK, p-YB-1 and p-Akt in LNCaP (A) and PC-3 (B) cells transfected with control siRNA and not treated with EGF was defined as 1. Boxes, mean; bars, plus-minus s.d.; *P < 0.05 versus cells with transfected with control siRNA
Supplementary Figure 5 from Targeted Therapy for BRAFV600E Malignant Astrocytoma
Authors: Nicolaides Theodore P. , Li Huifang , Solomon David A. , Hariono Sujatmi , Hashizume Rintaro , Barkovich Krister , Baker Suzanne J. , Paugh Barbara S. , Jones Chris , Forshew Tim , Hindley Guy F. , Hodgson J. Graeme , Kim Jung-Sik , Rowitch David H. , Weiss William A. , Waldman Todd A. , James C. David
Published: April 2023

PDF file - 154K
Supplementary figures 1 to 3 from Genotype-Specific Abnormalities in Mitochondrial Function Associate with Distinct Profiles of Energy Metabolism and Catecholamine Content in Pheochromocytoma and Paraganglioma
Authors: Rao Jyotsna U. , Engelke Udo F.H. , Rodenburg Richard J.T. , Wevers Ron A. , Pacak Karel , Eisenhofer Graeme , Qin Nan , Kusters Benno , Goudswaard Angelina G. , Lenders Jacques W.M. , Hermus Ad R.M.M. , Mensenkamp Arjen R. , Kunst Henricus P.M. , Sweep Fred C.G.J. , Timmers Henri J.L.M.
Published: April 2023

Supplementary Figure 1 Examples of 1H NMR spectra for different genotypes A. Example of NMR spectrum of a sporadic tumor depicting the peak positions of lactic acid, acetic acid and catecholamines. B. Example of NMR spectrum of a SDHB tumor depicting peak position of succinic acid. C. Example of NMR spectrum of a RET tumor depicting ATP/ADP/AMP and adrenaline specific peaks. Supplementary Figure 2 Comparison of epinephrine and norepinephrine content in tumor tissues as determined by HPLC and 1H-NMR spectroscopy. Passing - Bablok regression plot to compare measurement of epinephrine and norepinephrine content in PGL tumor tissues by HPLC and 1HNMR spectroscopy expressed as μg per mg tissue in Log10 scale. Supplementary Figure 3: Activities of respiratory chain complex II and tumor tissue succinate content in SDH related tumors. Black bars represent complex II activity expressed in mU/mg protein and grey bars represent tumor tissue succinate content in mmol/mg tissue for each individual tumor. Represented on X axis is the hereditary mutation in the patient from whom the tumor was resected.
Supplementary Figure 2 from Targeted Therapy for BRAFV600E Malignant Astrocytoma
Authors: Nicolaides Theodore P. , Li Huifang , Solomon David A. , Hariono Sujatmi , Hashizume Rintaro , Barkovich Krister , Baker Suzanne J. , Paugh Barbara S. , Jones Chris , Forshew Tim , Hindley Guy F. , Hodgson J. Graeme , Kim Jung-Sik , Rowitch David H. , Weiss William A. , Waldman Todd A. , James C. David
Published: April 2023

PDF file - 86K
Supplementary Figure 4 from Randomized Phase Ib/II Trial of Rilotumumab or Ganitumab with Panitumumab versus Panitumumab Alone in Patients with Wild-type KRAS Metastatic Colorectal Cancer
Authors: Van Cutsem Eric , Eng Cathy , Nowara Elzbieta , Świeboda-Sadlej Anna , Tebbutt Niall C. , Mitchell Edith , Davidenko Irina , Stephenson Joe , Elez Elena , Prenen Hans , Deng Hongjie , Tang Rui , McCaffery Ian , Oliner Kelly S. , Chen Lisa , Gansert Jennifer , Loh Elwyn , Smethurst Dominic , Tabernero Josep
Published: April 2023

PDF file - 37K, Supplemental Fig. S4. The effect of baseline IGF and IGF-related protein expression on overall survival.
Supplementary Figure 2 from Elevation of c-FLIP in Castrate-Resistant Prostate Cancer Antagonizes Therapeutic Response to Androgen Receptor–Targeted Therapy
Authors: McCourt Clare , Maxwell Pamela , Mazzucchelli Roberta , Montironi Rodolfo , Scarpelli Marina , Salto-Tellez Manuel , O'Sullivan Joe M. , Longley Daniel B. , Waugh David J.J.
Published: April 2023

PDF file, 252KB, The HDAC inhibitor Droxinostat down-regulates c-FLIP expression in androgen-dependent CaP cells and potentiates bicalutamide-induced apoptosis.
Supplementary Figure 2 from Analysis of Receptor Tyrosine Kinase ROS1-Positive Tumors in Non–Small Cell Lung Cancer: Identification of a FIG-ROS1 Fusion
Authors: Rimkunas Victoria M. , Crosby Katherine E. , Li Daiqiang , Hu Yerong , Kelly Meghan E. , Gu Ting-Lei , Mack Jennifer S. , Silver Matthew R. , Zhou Xinmin , Haack Herbert
Published: April 2023

PDF file, 5111KB, (A) A representative image of ALK break apart FISH (yellow arrows point to break apart). Images of ALK /L858R positive lung adenocarcinoma stained with (B) ALK D5F3, (C) total EGFR, (D) EGFR A746-E750del and (E) EGFR L858R antibodies.
Supplementary Figure 1 from Resistance to TRAIL Is Mediated by DARPP-32 in Gastric Cancer
Authors: Belkhiri Abbes , Zhu Shoumin , Chen Zheng , Soutto Mohammed , El-Rifai Wael
Published: April 2023

PDF file, 144KB, DARPP-32 has no significant effect on NF-kB activation in MKN-28 cells.
Supplementary Table 4 from Using Pharmacokinetic and Pharmacodynamic Data in Early Decision Making Regarding Drug Development: A Phase I Clinical Trial Evaluating Tyrosine Kinase Inhibitor, AEE788
Authors: Baselga José , Mita Alain C. , Schöffski Patrick , Dumez Herlinde , Rojo Frederico , Tabernero Josep , DiLea Clifford , Mietlowski William , Low Christie , Huang Jerry , Dugan Margaret , Parker Kathryn , Walk Eric , van Oosterom Allan , Martinelli Erika , Takimoto Chris H.
Published: April 2023

PDF file - 59K, Pharmacodynamic Parameters
Supplementary Table 3 from Using Pharmacokinetic and Pharmacodynamic Data in Early Decision Making Regarding Drug Development: A Phase I Clinical Trial Evaluating Tyrosine Kinase Inhibitor, AEE788
Authors: Baselga José , Mita Alain C. , Schöffski Patrick , Dumez Herlinde , Rojo Frederico , Tabernero Josep , DiLea Clifford , Mietlowski William , Low Christie , Huang Jerry , Dugan Margaret , Parker Kathryn , Walk Eric , van Oosterom Allan , Martinelli Erika , Takimoto Chris H.
Published: April 2023

PDF file - 56K, Mean Pharmacokinetic Parameters
Supplementary Figure 1 from IL-17–Mediated M1/M2 Macrophage Alteration Contributes to Pathogenesis of Bisphosphonate-Related Osteonecrosis of the Jaws
Authors: Zhang Qunzhou , Atsuta Ikiru , Liu Shiyu , Chen Chider , Shi Shihong , Shi Songtao , Le Anh D.
Published: April 2023

PDF file - 348K, Examination of M1 and M2 macrophages in smeared socket tissues of BRONJ patients.
Supplementary Methods and Figure 1 from Challenges in the Enumeration and Phenotyping of CTC
Authors: Coumans Frank A.W. , Ligthart Sjoerd T. , Uhr Jonathan W. , Terstappen Leon W.M.M.
Published: April 2023

PDF file, 120K, Supplemental with detailed information regarding patient inclusion/exclusion criteria for all studies. Reasons for exclusion whenever available and a summary of study characteristics and patient demographics.
Supplementary Figures 1 - 3 from Cap-Translation Inhibitor, 4EGI-1, Restores Sensitivity to ABT-737 Apoptosis through Cap-Dependent and -Independent Mechanisms in Chronic Lymphocytic Leukemia
Authors: Willimott Shaun , Beck Daniel , Ahearne Matthew J. , Adams Victoria C. , Wagner Simon D.
Published: April 2023

PDF file - 665K, Supplemental Figure 1 Trace from a sucrose density gradient separation of lysates made from the MCF7 cell line. Supplemental Figure 2 BCL2 family protein expression in response to 4EGI-1 Supplemental Figure 3 Relative expression of pro-survival proteins and synergy between 4EGI-1 and ABT-737 across a range of expression levels.
Supplementary Table 6 from Research-Based PAM50 Subtype Predictor Identifies Higher Responses and Improved Survival Outcomes in HER2-Positive Breast Cancer in the NOAH Study
Authors: Prat Aleix , Bianchini Giampaolo , Thomas Marlene , Belousov Anton , Cheang Maggie C.U. , Koehler Astrid , Gómez Patricia , Semiglazov Vladimir , Eiermann Wolfgang , Tjulandin Sergei , Byakhow Mikhail , Bermejo Begoña , Zambetti Milvia , Vazquez Federico , Gianni Luca , Baselga José
Published: April 2023

PDF file - 104K, Ability of the HER2-E subtype to predict pCR in 91 patients with clinically HER2-positive disease treated with trastuzumab-based chemotherapy in the ISPY-1, MDACC and XeNA studies.
Supplementary Figure 2 from Regulation of Colorectal Carcinoma Stemness, Growth, and Metastasis by an miR-200c-Sox2–Negative Feedback Loop Mechanism
Authors: Lu Yan-Xia , Yuan Li , Xue Xiao-Lei , Zhou Min , Liu Yan , Zhang Chao , Li Jing-Ping , Zheng Lin , Hong Min , Li Xue-Nong
Published: April 2023

PDF file - 223KB, Showed that down-regulation of miR-200c promoted tumour growth and metastasis of CRC in vitro.
Related Article from Intratumoral Anti-CTLA-4 Therapy: Enhancing Efficacy While Avoiding Toxicity
Authors: Marabelle Aurélien , Kohrt Holbrook , Levy Ronald
Published: April 2023

Related Article from Intratumoral Anti-CTLA-4 Therapy: Enhancing Efficacy While Avoiding Toxicity
Related Article from Targeting Metabolic Scavenging in Pancreatic Cancer
Authors: Lyssiotis Costas A. , Cantley Lewis C.
Published: April 2023

Related Article from Targeting Metabolic Scavenging in Pancreatic Cancer
Supplementary Figure 7 from Targeting Epithelial-to-Mesenchymal Transition with Met Inhibitors Reverts Chemoresistance in Small Cell Lung Cancer
Authors: Cañadas Israel , Rojo Federico , Taus Álvaro , Arpí Oriol , Arumí-Uría Montserrat , Pijuan Lara , Menéndez Silvia , Zazo Sandra , Dómine Manuel , Salido Marta , Mojal Sergi , García de Herreros Antonio , Rovira Ana , Albanell Joan , Arriola Edurne
Published: April 2023

PDF file - 40K, Kaplan-Meier curves for overall survival univariate analysis according to biomarker status.
Supplementary Figure 6 from Targeting Epithelial-to-Mesenchymal Transition with Met Inhibitors Reverts Chemoresistance in Small Cell Lung Cancer
Authors: Cañadas Israel , Rojo Federico , Taus Álvaro , Arpí Oriol , Arumí-Uría Montserrat , Pijuan Lara , Menéndez Silvia , Zazo Sandra , Dómine Manuel , Salido Marta , Mojal Sergi , García de Herreros Antonio , Rovira Ana , Albanell Joan , Arriola Edurne
Published: April 2023

PDF file - 354K, PF-2341066 sensitizes H841-derived xenografts cells to chemotherapy.
Supplementary Tables S1-7 and S9-10 from A Poor Prognosis Subtype of HNSCC Is Consistently Observed across Methylome, Transcriptome, and miRNome Analysis
Authors: Jung Alain C. , Job Sylvie , Ledrappier Sonia , Macabre Christine , Abecassis Joseph , de Reyniès Aurélien , Wasylyk Bohdan
Published: April 2023

Supplementary Tables S1-7 and S9-10 - PDF file 187K, This file contains the Supplementary Tables S1-7 and S9-10 together with their titles and legends. The contents are: Table S1: Examples from the literature of genome-wide profiling efforts of HNSCC. Table S2: Details of the available data for each of the 100 patient tumors. Table S3: Contingency tables to compare the C1-4 clusters identified in Rickman et al., (2008) and the T.1-3 clusters and R1/non-R1 groups described in the current study. Table S4: Survival analysis. Table S5: Characteristics of patients for the methylome validation. Table S6: p-values of the Fisher exact tests between the subgroup R1 and clinical criteria. Table S7: Pathways differentially regulated in R1 with methylome, transcriptome and miRNome data. Table S9: T-test of differential expression and fold change (FC) of expression in the R1 subgroup of genes located in the 13q14.2-3 cytoband. Table S10: Q-values of the differential expression of selected miRNAs between R1 and non-R1 samples.
Supplementary Figure 1 from Phase I Safety, Pharmacokinetic, and Pharmacodynamic Study of SAR245408 (XL147), an Oral Pan-Class I PI3K Inhibitor, in Patients with Advanced Solid Tumors
Authors: Shapiro Geoffrey I. , Rodon Jordi , Bedell Cynthia , Kwak Eunice L. , Baselga Jose , Braña Irene , Pandya Shuchi S. , Scheffold Christian , Laird A. Douglas , Nguyen Linh T. , Xu Yi , Egile Coumaran , Edelman Gerald
Published: April 2023

PDF file - 458K, Individual and mean SAR245408 pharmacokinetic parameters.
Supplementary Figure 7 from TP53 Mutation Spectrum in Breast Cancer Is Subtype Specific and Has Distinct Prognostic Relevance
Authors: Silwal-Pandit Laxmi , Vollan Hans Kristian Moen , Chin Suet-Feung , Rueda Oscar M. , McKinney Steven , Osako Tomo , Quigley David A. , Kristensen Vessela N. , Aparicio Samuel , Børresen-Dale Anne-Lise , Caldas Carlos , Langerød Anita
Published: April 2023

PDF file - 38KB, Figure S7. Kaplan-Meier survival curves showing BCSS of TP53 mutations status in ICs. Numbers at risk are listed below each chart (e = no. of Breast Cancer specific deaths).
Supplementary Tables 1-2 from A Pharmacokinetic/Pharmacodynamic Model of Tumor Lysis Syndrome in Chronic Lymphocytic Leukemia Patients Treated with Flavopiridol
Authors: Ji Jia , Mould Diane R. , Blum Kristie A. , Ruppert Amy S. , Poi Ming , Zhao Yuan , Johnson Amy J. , Byrd John C. , Grever Michael R. , Phelps Mitch A.
Published: April 2023

PDF file - 79 KB, Supplementary Table 1. Patient Characteristics Supplementary Table 2. Summary of drop-outs in Cycle 1
Supplementary Figure 2 from Reverse-Phase Protein Array Profiling of Oropharyngeal Cancer and Significance of PIK3CA Mutations in HPV-Associated Head and Neck Cancer
Authors: Sewell Andrew , Brown Brandee , Biktasova Asel , Mills Gordon B. , Lu Yiling , Tyson Darren R. , Issaeva Natalia , Yarbrough Wendell G.
Published: April 2023

PDF file - 200KB, Immunoblotting of HPV(+) SCC090 cells stably transfected with either wild type or E545K mutant PIK3CA vectors with pS6, pS6K and pAKT antibodies. Actin antibody was used as a loading control.
Supplementary Figure 3 from A Tumorigenic Factor Interactome Connected through Tumor Suppressor MicroRNA-198 in Human Pancreatic Cancer
Authors: Marin-Muller Christian , Li Dali , Bharadwaj Uddalak , Li Min , Chen Changyi , Hodges Sally E. , Fisher William E. , Mo Qianxing , Hung Mien-Chie , Yao Qizhi
Published: April 2023

Supplementary Figure 3 - PDF file 142K, miR-198 modulation in stable cell lines
Supplementary Figure Legend from Mesothelin Overexpression Is a Marker of Tumor Aggressiveness and Is Associated with Reduced Recurrence-Free and Overall Survival in Early-Stage Lung Adenocarcinoma
Authors: Kachala Stefan S. , Bograd Adam J. , Villena-Vargas Jonathan , Suzuki Kei , Servais Elliot L. , Kadota Kyuichi , Chou Joanne , Sima Camelia S. , Vertes Eva , Rusch Valerie W. , Travis William D. , Sadelain Michel , Adusumilli Prasad S.
Published: April 2023

PDF file - 96K
Supplementary Figure Legend from SHP2 Is Overexpressed and Inhibits pSTAT1-Mediated APM Component Expression, T-cell Attracting Chemokine Secretion, and CTL Recognition in Head and Neck Cancer Cells
Authors: Leibowitz Michael S. , Srivastava Raghvendra M. , Andrade Filho Pedro A. , Egloff Ann Marie , Wang Lin , Seethala Raja R. , Ferrone Soldano , Ferris Robert L.
Published: April 2023

PDF file - 62K
Supplementary Figure 2 from SHP2 Is Overexpressed and Inhibits pSTAT1-Mediated APM Component Expression, T-cell Attracting Chemokine Secretion, and CTL Recognition in Head and Neck Cancer Cells
Authors: Leibowitz Michael S. , Srivastava Raghvendra M. , Andrade Filho Pedro A. , Egloff Ann Marie , Wang Lin , Seethala Raja R. , Ferrone Soldano , Ferris Robert L.
Published: April 2023

PDF file - 44K, SHP2 depletion does not upregulate pSTAT3
Supplementary Table 9 from Identification of Campath-1 (CD52) as Novel Drug Target in Neoplastic Stem Cells in 5q-Patients with MDS and AML
Authors: Blatt Katharina , Herrmann Harald , Hoermann Gregor , Willmann Michael , Cerny-Reiterer Sabine , Sadovnik Irina , Herndlhofer Susanne , Streubel Berthold , Rabitsch Werner , Sperr Wolfgang R. , Mayerhofer Matthias , Rülicke Thomas , Valent Peter
Published: April 2023

PDF file - 61K, Supplementary Table S9: Detection of del(5q) in sorted cells of MDS patients by FISH.
Supplementary Figure 3 from Identification of Campath-1 (CD52) as Novel Drug Target in Neoplastic Stem Cells in 5q-Patients with MDS and AML
Authors: Blatt Katharina , Herrmann Harald , Hoermann Gregor , Willmann Michael , Cerny-Reiterer Sabine , Sadovnik Irina , Herndlhofer Susanne , Streubel Berthold , Rabitsch Werner , Sperr Wolfgang R. , Mayerhofer Matthias , Rülicke Thomas , Valent Peter
Published: April 2023

PDF file - 103K, Supplementary Figure S3: Expression of CD52 on CD34+/CD38− cells in different WHO subtypes of MDS and AML.
Supplementary Figure 4 from In Situ Tumor PD-L1 mRNA Expression Is Associated with Increased TILs and Better Outcome in Breast Carcinomas
Authors: Schalper Kurt A. , Velcheti Vamsidhar , Carvajal Daniel , Wimberly Hallie , Brown Jason , Pusztai Lajos , Rimm David L.
Published: April 2023

PDF file - 10619K, Figure S4. Characterization of TILs subtypes in breast carcinomas with low and high PD-L1 mRNA.
Supplementary Table S5 from The Activation of the WNT Signaling Pathway Is a Hallmark in Neurofibromatosis Type 1 Tumorigenesis
Authors: Luscan Armelle , Shackleford Ghjuvan'Ghjacumu , Masliah-Planchon Julien , Laurendeau Ingrid , Ortonne Nicolas , Varin Jennifer , Lallemand François , Leroy Karen , Dumaine Valérie , Hivelin Mikael , Borderie Didier , De Raedt Thomas , Valeyrie-Allanore Laurence , Larousserie Frédérique , Terris Benoît , Lantieri Laurent , Vidaud Michel , Vidaud Dominique , Wolkenstein Pierre , Parfait Béatrice , Bièche Ivan , Massaad Charbel , Pasmant Eric
Published: April 2023

PDF file 71K, mRNA expression of 24 identified genes in four sporadic MPNSTs
Supplementary Figure 3 from In Situ Tumor PD-L1 mRNA Expression Is Associated with Increased TILs and Better Outcome in Breast Carcinomas
Authors: Schalper Kurt A. , Velcheti Vamsidhar , Carvajal Daniel , Wimberly Hallie , Brown Jason , Pusztai Lajos , Rimm David L.
Published: April 2023

PDF file - 6598K, Figure S3. Association between PD-L1 protein and mRNA expression in breast cancer.
Supplementary Figures from Inhibition of RET Increases the Efficacy of Antiestrogen and Is a Novel Treatment Strategy for Luminal Breast Cancer
Authors: Spanheimer Philip M. , Park Jung-Min , Askeland Ryan W. , Kulak Mikhail V. , Woodfield George W. , De Andrade James P. , Cyr Anthony R. , Sugg Sonia L. , Thomas Alexandra , Weigel Ronald J.
Published: April 2023

PDF file 70K, Supplementary Figure 1. RET expression with Drug Treatment; Supplementary Figure 2. RET Protein Expression in a Subset of Primary Cancers
Supplementary Figure Legends from Anti-PD-1 Antibody Therapy Potently Enhances the Eradication of Established Tumors By Gene-Modified T Cells
Authors: John Liza B. , Devaud Christel , Duong Connie P.M. , Yong Carmen S. , Beavis Paul A. , Haynes Nicole M. , Chow Melvyn T. , Smyth Mark J. , Kershaw Michael H. , Darcy Phillip K.
Published: April 2023

Supplementary Figure Legends - PDF file 66K, Supplementary Figure legends
Supplementary Figure 2 from Downregulation of miR-138 Sustains NF-κB Activation and Promotes Lipid Raft Formation in Esophageal Squamous Cell Carcinoma
Authors: Gong Hui , Song Libing , Lin Chuyong , Liu Aibin , Lin Xi , Wu Jueheng , Li Mengfeng , Li Jun
Published: April 2023

PDF file - 234 KB, Downregulation of miR-138 promotes the aggressiveness of ESCC cells in vitro.
Supplementary Figs 1, 2 from CD137 Accurately Identifies and Enriches for Naturally Occurring Tumor-Reactive T Cells in Tumor
Authors: Ye Qunrui , Song De-Gang , Poussin Mathilde , Yamamoto Tori , Best Andrew , Li Chunsheng , Coukos George , Powell Daniel J.
Published: April 2023

CD137 Supplementary Figs 1, 2 - PDF file 169K, Supplementary Figure 1. Ovarian cancer containing tumor specific reactive T cells. Supplementary Figure 2. CD137-enriched ovarian cancer TILs slow tumor growth in vivo.
Supplementary Figure Legends from CD62L as a Therapeutic Target in Chronic Lymphocytic Leukemia
Authors: Burgess Melinda , Gill Devinder , Singhania Richa , Cheung Catherine , Chambers Lynne , Renyolds Brent A. , Smith Louise , Mollee Peter , Saunders Nicholas , McMillan Nigel AJ
Published: April 2023

Supplementary Figure Legends - PDF files 57K, Figure Legends
Supplementary Figure 2 from CD62L as a Therapeutic Target in Chronic Lymphocytic Leukemia
Authors: Burgess Melinda , Gill Devinder , Singhania Richa , Cheung Catherine , Chambers Lynne , Renyolds Brent A. , Smith Louise , Mollee Peter , Saunders Nicholas , McMillan Nigel AJ
Published: April 2023

Supplementary Figure 2 - PDF files 805K, Correlation of CD62L antibody responses and clinical parameters
Supplementary Figure 2 from CTLA4 Blockade Broadens the Peripheral T-Cell Receptor Repertoire
Authors: Robert Lidia , Tsoi Jennifer , Wang Xiaoyan , Emerson Ryan , Homet Blanca , Chodon Thinle , Mok Stephen , Huang Rong Rong , Cochran Alistair J. , Comin-Anduix Begoña , Koya Richard C. , Graeber Thomas G. , Robins Harlan , Ribas Antoni
Published: April 2023

PDF file - 48KB, Lack of correlations between changes in ALC (x axis) and changes in the unique productive sequences (y axis) expressed in % of change both. Each dot corresponds to a GA patient.
Supplementary Figure 3 from The Histone Deacetylase Inhibitor Abexinostat Induces Cancer Stem Cells Differentiation in Breast Cancer with Low Xist Expression
Authors: Salvador Marion A. , Wicinski Julien , Cabaud Olivier , Toiron Yves , Finetti Pascal , Josselin Emmanuelle , Lelièvre Hélène , Kraus-Berthier Laurence , Depil Stéphane , Bertucci François , Collette Yves , Birnbaum Daniel , Charafe-Jauffret Emmanuelle , Ginestier Christophe
Published: April 2023

PDF file 109K, Conventional molecular parameters do not predict drug-response to abexinostat
Supplementary Table S2 from Inhibition of Tumor Growth and Metastasis in Non–Small Cell Lung Cancer by LY2801653, an Inhibitor of Several Oncokinases, Including MET
Authors: Wu Wenjuan , Bi Chen , Credille Kelly M. , Manro Jason R. , Peek Victoria L. , Donoho Gregory P. , Yan Lei , Wijsman John A. , Yan S. Betty , Walgren Richard A.
Published: April 2023

Supplementary Table S2 - PDF file 88K, Inhibition of tumor growth
Supplementary Figure 3 from Prespecified Candidate Biomarkers Identify Follicular Lymphoma Patients Who Achieved Longer Progression-Free Survival with Bortezomib–Rituximab Versus Rituximab
Authors: Coiffier Bertrand , Li Weimin , Henitz Erin D. , Karkera Jayaprakash D. , Favis Reyna , Gaffney Dana , Shapiro Alice , Theocharous Panteli , Elsayed Yusri A. , van de Velde Helgi , Schaffer Michael E. , Osmanov Evgenii A. , Hong Xiaonan , Scheliga Adriana , Mayer Jiri , Offner Fritz , Rule Simon , Teixeira Adriana , Romejko-Jarosinska Joanna , de Vos Sven , Crump Michael , Shpilberg Ofer , Zinzani Pier Luigi , Cakana Andrew , Esseltine Dixie-Lee , Mulligan George , Ricci Deborah
Published: April 2023

Supplementary Figure 3 PDF file 78K, Kaplan-Meier distributions of A) PFS and B) OS under the G-dominant genetic model for PSMB1 P11A among all patients evaluable for the biomarker pair of PSMB1 P11A genotype and CD68 expression who had low (≤50 CD68-positive cells) CD68 expression
Supplementary Tables 1 - 3 from Zoledronic Acid Has Differential Antitumor Activity in the Pre- and Postmenopausal Bone Microenvironment In Vivo
Authors: Ottewell Penelope D. , Wang Ning , Brown Hannah K. , Reeves Kimberly J. , Fowles C. Anne , Croucher Peter I. , Eaton Colby L. , Holen Ingunn
Published: April 2023

PDF file - 182KB, Effects of ovariectomy and zoledronic acid treatment on serum bone turnover markers and gene expression in mouse long bones.
Fig. S7 from The Disparate Twins: A Comparative Study of CXCR4 and CXCR7 in SDF-1α–Induced Gene Expression, Invasion and Chemosensitivity of Colon Cancer
Authors: Heckmann Doreen , Maier Patrick , Laufs Stephanie , Li Li , Sleeman Jonathan P. , Trunk Marcus J. , Leupold Jörg H. , Wenz Frederik , Zeller W. Jens , Fruehauf Stefan , Allgayer Heike
Published: April 2023

PDF file 154K, S7: Correlation analysis of expression of miR-217, miR-218 and their respective targets RIN2, EFNB2, and DUSP5 in tumor tissue with various clinicopathological features
Supplementary Figure Legends, Table 1 from Prognostic and Therapeutic Implications of Aromatase Expression in Lung Adenocarcinomas with EGFR Mutations
Authors: Kohno Mikihiro , Okamoto Tatsuro , Suda Kenichi , Shimokawa Mototsugu , Kitahara Hirokazu , Shimamatsu Shinichiro , Konishi Hideyuki , Yoshida Tsukihisa , Takenoyama Mitsuhiro , Yano Tokujiro , Maehara Yoshihiko
Published: April 2023

PDF file - 69KB, Supplementary Table S1. Multivariate analysis of predictive factors for high aromatase expression (n = 110).
Supplementary Figure 1 from The Ubiquitin–CXCR4 Axis Plays an Important Role in Acute Lung Infection–Enhanced Lung Tumor Metastasis
Authors: Yan Libo , Cai Qingchun , Xu Yan
Published: April 2023

PDF file - 164K, The combination of the bacterial pneumonia model and the experimental lung metastasis model.
Supplementary Table 2 from Phase II Results of Dovitinib (TKI258) in Patients with Metastatic Renal Cell Cancer
Authors: Escudier Bernard , Grünwald Viktor , Ravaud Alain , Ou Yen-Chuan , Castellano Daniel , Lin Chia-Chi , Gschwend Jürgen E. , Harzstark Andrea , Beall Sarah , Pirotta Nicoletta , Squires Matthew , Shi Michael , Angevin Eric
Published: April 2023

PDF file - 25KB, Supplemental Table 2 contains a summary of the newly occurring qualitative ECG abnormalities.
Supplementary Table 1 from Phase II Results of Dovitinib (TKI258) in Patients with Metastatic Renal Cell Cancer
Authors: Escudier Bernard , Grünwald Viktor , Ravaud Alain , Ou Yen-Chuan , Castellano Daniel , Lin Chia-Chi , Gschwend Jürgen E. , Harzstark Andrea , Beall Sarah , Pirotta Nicoletta , Squires Matthew , Shi Michael , Angevin Eric
Published: April 2023

PDF file - 22KB, Supplemental Table 1 contains the pharmacokinetic results from the study.
Supplementary Figure 2 from Frequent Overexpression of HMGA2 in Human Atypical Teratoid/Rhabdoid Tumor and Its Correlation with let-7a3/let-7b miRNA
Authors: Zhang Keqiang , Gao Hanlin , Wu Xiwei , Wang Jinhui , Zhou Wendi , Sun Guihua , Wang Jinghan , Wang Yafan , Mu Bing , Kim Charles , Chu Peiguo , Ho Donald M. , Ann David K. , Wong Tai-Tong , Yen Yun
Published: April 2023

PDF file - 382K, Figure S2.The relative whole exome copy number of genomic DNA from FFPE AT/RT tissue (normalized to genomic DNA extracted from saliva).
Supplementary Fig S2 from Novel Methylation Biomarker Panel for the Early Detection of Pancreatic Cancer
Authors: Yi Joo Mi , Guzzetta Angela A. , Bailey Vasudev J. , Downing Stephanie R. , Van Neste Leander , Chiappinelli Katherine B. , Keeley Brian P. , Stark Alejandro , Herrera Alexander , Wolfgang Christopher , Pappou Emmanouil P. , Iacobuzio-Donahue Christine A. , Goggins Michael G. , Herman James G. , Wang Tza-Huei , Baylin Stephen B. , Ahuja Nita
Published: April 2023

- PDF file 108K, Supplementary Figure S2. mRNA and Protein Expression in BNC1 Overexpression System
Supplemental Table 1 from Influence of Human OATP1B1, OATP1B3, and OATP1A2 on the Pharmacokinetics of Methotrexate and Paclitaxel in Humanized Transgenic Mice
Authors: van de Steeg Evita , van Esch Anita , Wagenaar Els , Kenworthy Kathryn E. , Schinkel Alfred H.
Published: April 2023

PDF file - 101K, Tabular RT-PCR analysis results about the expression of other transporter proteins in livers of knockout and humanized transgenic OATP mice