bluuebunny/crossref_metadata_2025 huggingface dataset:
Hypoglycemic states and coma in diabetes mellitus
Authors: Sultanova L. M. , Khasanov E. N.
Published: March 2022

Hypoglycemic conditions are not so rare in the work of a practicing physician, primarily an emergency physician. Of particular importance are hypoglycemia in patients with diabetes mellitus, developing against the background of insulin therapy, less often - during treatment with sugar-lowering sulfonamide drugs (chlorpropamide, glibenclamide). Diagnostic errors and difficulties are observed in the emergency care setting. Hypoglycemic conditions associated with insulin therapy of diabetes occur in 35-55% of patients.
Treatment of purulent wounds in diabetic patients with low-frequency ultrasound combined with helium-neon laser
Authors: Khurshudyan A. G.
Published: March 2022

Acute surgical infection in diabetes mellitus is still one of the difficult problems of practical medicine and requires more in-depth research.

The aim of this work was to determine the effectiveness of treatment of acute pyo-inflammatory diseases of soft tissues in diabetic patients with ultrasound treatment of wounds with low-frequency ultrasound and subsequent stimulation of reparative processes in them by radiation of low-intensity helium-neon-based laser.
Clinical significance of renal cytomembrane condition in pediatric diabetes mellitus
Authors: Mrasova V. K. , Sultanova L. M.
Published: March 2022

Renal failure associated with diabetic angionephropathy is the immediate cause of death in approximately 50% of patients with type I diabetes in childhood. It is important for the physician to identify preclinical signs of kidney damage, because the clinical symptoms of diabetic angioedema are indicative of the unfolding pattern of vascular complications.
Current views on the X-ray diagnosis of birth injuries of the spine and spinal cord in children
Authors: Mikhailov M. K.
Published: March 2022

The progress of health care today depends to a large extent on the progress in pediatrics, the level of infant mortality and health indicators of children, especially in the first year of life. Therefore, it is no coincidence that the problems of perinatal pathology are among the highest priorities in modern medicine. Pediatric neurologists have been able to show and prove that a huge place in perinatology is occupied by birth injuries of the nervous system. Even minimal trauma, depending on which structures are damaged, can lead to irreversible changes up to and including death.
Experience in rehabilitation of orthopedic and traumatologic patients at the production association
Authors: Evseev V. I. , Martynyuk L. Ya. , Saifullin Sh. M.
Published: March 2022

This paper summarizes the experience of industrial rehabilitation of patients with orthopedic-traumatologic profile in the department of rehabilitation treatment of medical unit of "Izhmash" production association, which has been functioning since December 1983 as a part of a polyclinic and has an industrial rehabilitation section. The department includes water and mud baths, physical therapy, electrotherapy, mechanotherapy and massage therapy rooms. The industrial rehabilitation section includes three classrooms for assembling "Moskvich" car parts.
Therapeutic exercise in the complex treatment of victims of femur fractures
Authors: Prokopiev N. Ya. , Bakhtiozin V. F.
Published: March 2022

We have accumulated experience in the surgical treatment of diaphyseal fractures of the femur in 256 patients; closed intramedullary osteosynthesis was performed in 56 of them. Like a number of other authors, we performed this operation under the control of an electron-optical converter with bone marrow canal dissection. When the femoral canal is drilled out, part of the bone chips and bone marrow elements are embedded between the bone fragments, which improves the reparative process. This operation, which we perform usually on the 14th day after injury, does not damage the soft tissues in the fracture area, the periosteum and the femur itself. Fixation of bone fragments of the femur is performed using a powerful hollow metal nail with a slit, which, in our opinion, ensures stability of the fracture for the entire period of regeneration and saves the patient from additional external immobilization with a plaster cast with all its inherent drawbacks.
Extrafocal compression osteosynthesis of mandibular fractures and its biomechanical justification
Authors: Khamitov F. S. , Sabirov R. S. , Evseev V. I.
Published: March 2022

We studied the biomechanical features of mandibular fractures by mathematical modeling methods taking into account the data of direct and inverse gnathodinamometry. The forces of the masticatory muscles were measured strainsometrically. The following values of gnathodinamometry were taken for analysis of mathematical models of maxillofacial region: direct in central part - 21,28-28,28 kgf, in lateral parts - 37, 52-48,02 kgf; reverse - 7.26-11,16 kgf. Vectors of masticatory muscles and muscles of hyoid bone were studied mathematically.
Diagnosis of recurrent rheumatic heart disease and its gradation in severity
Authors: Starkova N. V.
Published: March 2022

The aim of the work was to develop diagnostic criteria for recurrent rheumatic heart disease and its variants differing in severity. To solve this question we used a complex of clinical, laboratory, instrumental data, as well as the results of pathological anatomical examination. WHO criteria with determination of streptococcal antibody titers were used during examination of soles. Besides routine methods of laboratory study, the state of body's immune system was evaluated: reaction of inhibition of leukocyte migration (RTML), titer of anti-streptococcal antibodies, measures of completed and incomplete phagocytosis, activity of blood serum acid phosphatase. The type and group of streptococcus were determined in nasopharyngeal smears. ECG and Echo-CG were recorded. The state of central hemodynamics was studied with mechanocardiography according to N.N. Savitsky.
Drug prophylaxis for the progression of myopia of mild to moderate degree
Authors: Nesterov A. P. , Svirin A. V. , Lapochkin V. I. , Batmanov Yu. E.
Published: March 2022

The prophylactic method developed by us (application for invention "Method of medication prophylaxis of myopia progression" No. 4171900/14-467 of 04.01.1987) is simple and not connected with any restrictions in everyday life, studies or work. Its implementation does not require significant labor and time from both medical personnel and the patient. Let us briefly describe the essence and substantiation of our method.
Radiological evaluation of laryngeal stenosis stage in acute laryngotracheitis in children
Authors: Batyrshin R. U.
Published: March 2022

The study was conducted in 228 children in whom pneumonia was suspected during clinical examination, complicating the course of acute laryngotracheitis. There were 46 children aged 8 months to 1 year, 113 from 1 to 2 years, and 69 from 2 to 3 years. Clinically, acute respiratory failure in 111 children corresponded to stage I laryngeal stenosis, in 104 to stage II, and in 13 to stage III. A group of 10 children suffering from pneumonia without combination with acute laryngotracheitis was taken for comparison.
On the mixed form of pathology in chronic alcoholism and cervical osteochondrosis
Authors: Enikeev D. G. , Bohan N. A.
Published: March 2022

It is known that biological background influences the course of the disease, causing the appearance of complex, mixed forms of pathology. The system-structural analysis of alcoholic pathology highlights neurological aggravation as a significant predisposing factor for unfavorable development of alcoholism. In studies of alcoholism clinical features in patients with neurological aggravation, predominantly traumatic, less often vascular brain lesions are considered, and premorbid brain impairment is assessed summarily, without taking into account the topics of the existing lesions and correlation of alcoholism syndrome-taxis to them.
Treatment of peptic ulcer of the stomach and duodenum with helium laser
Authors: Murzanov M. M. , Sakhautdinov G. V. , Khasanov A. G. , Urazbakhtin I. M.
Published: March 2022

We treated 160 patients (141 men and 19 women, the age of patients was from 18 to 67 years) with gastric and duodenal ulcers using a helium-neon laser LG-75 with an output power range from 15 to 35 mW. Laser radiation was injected into a quartz monofilament 4 mm in diameter and 3 m in length using a transient focusing device. The power of radiation at the output of the fiber was 85% of the initial one. In 127 patients the ulcer (size - 0,80,2 cm) was localized in the bulb of duodenum, in 33 patients - in the stomach (0,70,1 cm). The efficacy of treatment was judged by the dynamics of clinical, radiological, endoscopic and morphological parameters. Acid-producing function of the stomach was investigated by intragastric pH-metry, motor function - by electro gastrography. The therapeutic manipulations were performed daily or every other day for 5 min at a power density at the end of the glass fiber of 1.5-2X103 wt-m-2. In all cases laser therapy was started after histological and cytological examination of biopsy material.
Experience of polymeric film application for abdominal cavity drainage
Authors: Voitsekhovich V. N. , Chuprin V. G. , Dobrokvashin S. V.
Published: March 2022

In the Emergency Surgery Clinic of Kazan Emergency Medical Care Hospital since July 1986, for drainage of abdominal cavity after operations for various purulent processes, drains prepared from 10-50 microns thick elastic hydratecellulose film are used. A sheet of film is folded in the form of an accordion into a package with a rib width of 0.5-1 cm and a length of 10-30 cm; such a package usually has 10-15 planes. The draining effect of the hydrate cellulose film drainage is maintained throughout its stay in the abdominal cavity. However, such drainage also has certain disadvantages.
On the colonic mucosal barrier in patients with nonspecific ulcerative colitis
Authors: Kashkina E. I. , Rabinovich P. D.
Published: March 2022

Despite numerous studies, the etiology and pathonemesis of nonspecific ulcerative colitis have not yet been definitively elucidated. The main hypothesis explaining the occurrence of this disease is considered to be immunological. However, it has been repeatedly suggested that the state of protective mucosal barrier plays a certain role in its pathogenesis.
Study of natural focal diseases in island and shallow water ecosystems of Tataria reservoirs
Authors: Boyko V. A. , Goncharova M. I. , Yahod D. B. , Smirnova M. I. , Gavrilovskaya I. N. , Potapov V. S. , Abashev V. A. , Yarullova R. A.
Published: March 2022

Creation of Kuibyshev and Nizhnekamsk reservoirs radically changed the structure and functional activity of historically developed ecosystems of former floodplains of Volga and Kama rivers. Due to the abrupt change of hydrological regime, there were significant disturbances in parasitocenosis of some natural focal infections and invasions, epidemiological significance of which in the regional pathology of the republic's population was quite pronounced. Thus, flooding of typical habitats of water vole (floodplain lakes, marshes) led to a significant reduction in the number of the species in reservoirs and thereby weakened epizootic tension of natural foci of floodplain type tularemia.
Modified method for determining skin capillary resistance
Authors: Kondrashkin G. I.
Published: March 2022

Study of skin capillary resistance is of great importance when the reactivity of the body is changed under the influence of various physical and chemical factors. In this case predisposing factors may be a lack of UV radiation, lack of ascorbic acid and vitamin P in the body.
Significance of risk factors for autonomic dysfunction in childhood and adolescence for physical examination
Authors: Ismagilov M. F.
Published: March 2022

Autonomic nervous system dysfunction is a common and extremely diverse clinical phenomenon. Most of these disorders are designated by the term "autonomic dysfunction", or "vegetovascular dystonia", which has no nosological independence. This universal syndrome of homeostasis shifts often manifests itself during critical periods of ontogenesis and serves as a signal of incomplete well-being. One of such periods is pubertal age, a time of intense growth and morphofunctional restructuring of the body. Functional disorders of autonomic regulation during puberty may be the initial, reversible stage of diseases of various organs and systems that arose in early childhood.
The value of additional research methods in the diagnosis of cerebral infarction with a hemorrhagic component
Authors: Ashman A. A.
Published: March 2022

In the acute period of stroke, the study of cerebrospinal fluid composition and the results of one-dimensional echoencephaloscopy remain the most informative among the available additional methods. Some authors believe that in the absence of contraindications, analysis of cerebrospinal fluid should be performed in all patients, and refusal of the study should be considered a methodological error.
New tranquilizer Signopam in the complex treatment of prolonged neurosis
Authors: Enikeev D. G. , Zimakova I. E. , Semenikhin D. G.
Published: March 2022

Currently, there is a high incidence of neuroses in various countries. Patients with acute neuroses are successfully treated by therapists and neurologists. Qualified exclusion of somatic and other diseases that the patient suggests he has, convincing him of it, medication, including the use of tranquilizers, relieves the person of neurosis.
Hyperbaric oxygenation in the complex treatment of psychiatric disorders in inhalation toxicomania
Authors: Chudin A. S. , Epifanova N. M.
Published: March 2022

Recently, the problem of inhalation poisonings, observed as a rule, among children and adolescents who use substances used in household chemicals in order to achieve a euphoric state, has become increasingly important. Such substances have a selective toxic effect and cause tissue changes accompanied by organ and general hypoxia. This is the basis for the use of hyperbaric oxygenation, which has a powerful antihypoxic and disintoxicating effect as a means of pathogenetic therapy in this pathology, as well as psychoenergizing effect in various asthenic disorders.

The aim of the work is to find out the effect of hyperbaric oxygenation on the clinical course of acute period of intoxication in patients suffering from inhalation toxicomania.
Electromyographic analysis of motor units in patients with post-stroke hemiparesis
Authors: Bogdanov E. I. , Faskhutdinov R. R. , Galyamov D. L.
Published: March 2022

Among the mechanisms of motor disorders in central motor neuron lesions, along with changes in descending impulses to motoneurons, segmental disorders are also assumed. In 1879, Charcot proposed the hypothesis of transsynaptic degeneration of motoneurons in lesions of central motor neurons. Subsequently, changes in motoneurons in experimental and clinical lesions of the pyramidal tract were observed by many, though not all researchers. Charcot's theory received as if a new confirmation in electromyographic studies, which showed a decrease in the number of motor units and increase in the territories of the preserved motor units in the muscles of the affected side in patients with hemiplegia.
On the issue of uroflowmetry in children
Authors: Akhunzyanov A. A. , Asadullin Sh. G.
Published: March 2022

In the present work we consider uroflowmetry as a promising method of functional diagnostics in pediatric urological practice. Uroflowmetry is a method based on the measurement of volume urinary flow rate (VUR). The following parameters are recorded graphically: duration of urination, average urine flow rate, urine flow rate in the first second, time of reaching maximum urine flow rate, maximum urine flow rate and bladder volume.
Determination of the side of traumatic intracranial hematomas
Authors: Troshin V. M. , Lebedev A. V. , Frolova S. M.
Published: March 2022

It is crucial for the neurosurgeon to recognize the side of intracranial hematoma formation in patients with craniocerebral trauma. This task is no less difficult than determining its presence. In addition to the neurological picture, the nature and localization of injuries to the scalp and skull bones should be taken into account. Meanwhile, such a traditional symptom of intracranial hematoma, as pupil dilation, occurs in 15-20% of patients on the side opposite the hematoma. Homolateral pyramidal syndrome is not uncommon (about 20% of the victims). The existing clinical dissociations are usually due to either severe concomitant contusion of the cerebral hemisphere opposite to the side with the hematoma or to the developed dislocation of the stem formations.
Treatment of combined hand injuries
Authors: Nettov G. G.
Published: March 2022

Combined hand trauma is observed in 85.5% of cases in persons under 50 years of age and leads to loss of professional ability to work in 41.8% of cases and to disability in 19-43% of cases. Therefore, treatment of concomitant hand injuries remains an urgent problem at the present time. Due to diagnostic errors, 61.3% of patients with median and ulnar nerve injuries refer to specialists only 3 months after injury. Simple diagnostic tests have been suggested: inability to oppose the I finger, inability to grasp a cylindrical object with the I finger, which is typical for median nerve injury. If a patient cannot cross II and IV fingers over or under III finger, it indicates ulnar nerve damage, and if he is unable to strike the table with half-bent fingers (II-V), it means the median and ulnar nerves are injured.
Case of patellar arthroplasty
Authors: Osipenko N. E.
Published: March 2022

Knee fractures account for 1.5-2.2% of all skeletal injuries. While fractures of the patella without displacement are treated conservatively by applying a deep posterior plaster cast with a "drying" cast placed on the anterior surface of the joint, displaced fractures require surgical intervention. In the case of multiple comminuted and fractured patellar fractures with displacement, in which it is impossible to bring all fragments together using P-shaped lavsan or sutures, the best outcomes can be achieved by endoprosthesis, that is, removal of the entire fractured patella and replacing it with an endoprosthesis. In this report, we would like to share our experience with patellar endoprosthesis according to G.S. Samoilov performed for a multiaxial fracture in the hospital.
Development of babies delivered by cesarean section
Authors: Akhmadeeva E. N.
Published: March 2022

In order to prevent maternal and perinatal mortality, there has been a clear trend in the last decade to expand the indications for abdominal delivery. The frequency of cesarean section, according to different authors, ranges from 3-6.5 to 21.6%. At the same time, the immediate, short-term, and long-term results of cesarean section for a baby are insufficiently covered in the literature, and methodological approaches to nursing this group of children are not developed accordingly. Doctors often do not distinguish between abdominally and naturally delivered babies, and in some cases they consider cesarean section to be the optimal method of delivery for the fetus and the newborn. The first results of physiological studies of children born by cesarean section indicate that this operation is not indifferent to the newborn.
Laser reflexotherapy in the treatment of tobacco smoking
Authors: Yusupov A. S. , Vakhitova S. Kh. , Vasyuk S. P.
Published: March 2022

Tobacco smoking is the most common substance abuse problem of our time and one of the causes of many serious diseases, especially in developed countries. According to WHO data, total death rate among smokers in different countries exceeds death rate among non-smokers by 30-80%, and the most significant part of smokers dies at the age of 45-54 years, which is especially valuable in terms of professional experience. Every year there is a growing danger of harmful influence of tobacco smoking on reproduction of population, deterioration of younger generation health. All this makes treatment of tobacco smoking very urgent task of medicine.
A case of in vivo diagnosis of generalized idiopathic amyloidosis
Authors: Valimukhametova D. A. , Leonova V. N. , Reznikova F. A. , Khamzina S. K.
Published: March 2022

Idiopathic amyloidosis, unlike secondary amyloidosis, develops in the absence of previous disease. Its clinical presentation is multifaceted, determined by the lesion of certain organs and highly variable during the course of the disease. All manifestations of the disease are nonspecific. In contrast to secondary amyloidosis, idiopathic amyloidosis more often involves cardiovascular, respiratory, digestive and urinary systems. In vivo diagnosis of idiopathic amyloidosis is difficult due to its imitation of many diseases; in practice, it is recognized less often than it occurs.
Three cases of old uterine rupture
Authors: Fatkullin I. F. , Ershov A. T. , Diaz E. S.
Published: March 2022

It is known that uterine ruptures are the most serious obstetric pathology; without timely surgical care they usually lead to death due to hemorrhagic and painful shock or sepsis. Life expectancy of such patients is usually a few hours, less often - a few days. There are single reports in the special literature about uterine ruptures, which ended with spontaneous "cure" - favorable outcome for a woman.
Treatment of hypertension depending on the effect of beta-adrenoblockers on blood serum lipids and lipoproteins
Authors: Tikhonov V. P. , Umurzakov E. U. , Statsenko M. E. , Nemchuk F. A.
Published: March 2022

Beta-adrenergic receptor blockers are widely used in the treatment of hypertension. However, in recent years, there have been reports of their adverse effects on lipid metabolism - an increase in triglycerides, to a lesser extent in cholesterol and low-density lipoproteins, a decrease in high-density lipoproteins. At the same time, a number of authors did not note such results. Discrepancy in the data is primarily due to the heterogeneity of hypertensive patients, although analysis of the literature suggests that in some hypertensive patients the level of lipids and atherogenic lipoproteins may increase with prolonged treatment with propranolol.
Current features of diagnosis and treatment of Beck's sarcoidosis
Authors: Slepova R. I. , Galiaskarova E. R. , Domracheva O. V.
Published: March 2022

Despite the long history of studying sarcoidosis, many questions of etiology and pathogenesis, diagnosis and treatment of this disease have not yet been clarified. In recent years, the incidence of sarcoidosis has increased markedly. According to the data of diagnostic department of the Republican anti-TB Dispensary in 1970-1975 there were registered only 6 cases of sarcoidosis, but in 1976-1980 and 1981-1987 their number increased 6-8 times. An important factor in the inflow of sarcoidosis patients to TB dispensaries is the detection of such persons mainly during prophylactic fluorography. Doctors of various profiles - therapists, phthisiatricians, radiologists, oncologists and other specialists, who in their practical work experience certain difficulties in differential diagnosis, treatment and registration of these patients, have to deal with sarcoidosis patients.
Energy-frequency electroencephalogram parameters of diabetic patients depending on morphotype
Authors: Nasyrova E. G. , Lukina M. V. , Nizamutdinov S. I. , Smirnova M. V.
Published: March 2022

In diabetic patients the physique is characterized by android distribution of subcutaneous fat, i.e. excess in the neck, chin, back, abdomen and decrease in the extremities. Obviously, the characteristic morphotype is a particular manifestation of the general constitution.
Experience of extracorporeal detoxification in children with toxicosis of various etiologies
Authors: Gizatulin R. B. , Novikov N. I. , Andreev A. V. , Nasyrov R. F. , Shutov A. V. , Arkhipova E. E. , Shcheblanova E. E.
Published: March 2022

We summarized the experience of treatment of patients who were in the department of intensive care and intensive care of childhood (1983-1987), in which methods of extracorporeal detoxification were used in the complex of intensive care.
Medical ethics and deontology in disasters and catastrophes
Authors: Karatay Sh. S.
Published: March 2022

All mass lesions are characterized by such a basic common feature as a mismatch between the number of victims and the possibilities of rendering medical aid. It should be emphasized that the provision of medical care in disasters is significantly different from that which is possible in normal conditions. The decisive tasks and the organizational tactics change; the severity of the conditions with the time factor increases. The peculiarities of medical and tactical situation in disasters require further scientific and practical development of ethical and deontological principles, connected with the doctor's activity.
Application of helium-neon laser for arrhythmic shock management
Authors: Korobov V. V. , Mukhin G. B.
Published: March 2022

We observed several patients with arrhythmic shock in whom a favorable therapeutic effect was obtained using HeNe laser radiation in the complex therapy of arrhythmic shock. We present the following two observations.
Peculiarities of functional state of pituitary-adrenal system in patients with hypertension
Authors: Kryukov N. N.
Published: March 2022

We studied functional state of adenohypophyseal-adrenal system in hypertensive patients. 127 patients with hypertension of I and II stages according to WHO classification (59 men and 68 women) aged 17-60 years (mean age 48,7 years) were investigated. Patients with Stage I hypertension (Group I) had systolic and diastolic BP of 22.61.1 and 13.00.6 kPa, respectively (mean duration of disease: 4 years). Arterial hypertension in stage II patients (group 2) was stable, 25.41.3 and 14.71.1 kPa (mean duration of illness - 11 years). The control group included 32 healthy individuals.
Changes in nervous system function in women with subclinical forms of late gestosis of pregnant women
Authors: Atamanov A. G. , Novoshinova T. N.
Published: March 2022

We determined the functional state of the sympathetic-adrenal system (SAD) and electroencephalography data in women with subclinical forms of late gestosis in pregnant women.

32 women aged 20 to 35 years at 20 to 26 weeks' gestation underwent comprehensive examination. Twenty of them were first-pregnant and 12 were second-pregnant. Depending on the predicted form of late gestosis, the pregnant women were divided into two groups.
Republican conference "Topical issues of organization of outpatient and polyclinic care".
Authors: Nizamov I. G.
Published: March 2022

The conference was held within the framework of the implementation of the target comprehensive program "Health" for strengthening the prevention of diseases and strengthening the health of the population of the Tatar ASSR for 1986-1990. It focused on the issues of continuous improvement of labor conditions, sanitary and health measures, prevention of general and professional morbidity, traumatism, creation of good living and rest conditions for people. The conference was attended by the management of the TASSR Ministry of Health and the Republican Clinical Hospital, professors and lecturers of universities in Kazan, heads of Party and Soviet bodies of Bavly district, responsible employees of medical equipment department, pharmacy department, chief physicians of hospitals, polyclinics and their deputies.
Toxoplasmosis in clinical pathology
Authors: Moroz B. V. , Nikiforov V. N. , Tryakina I. P.
Published: March 2022

The significance of toxoplasmosis in clinical pathology has not yet been fully clarified. On the one hand, T. gondii is an opportunistic microorganism with low pathogenicity and evolutionarily adapted to long-term asymptomatic existence in the immune organism of its host, in particular humans; on the other hand, this parasite can activate up to life-threatening for the host if the latter has weakened or damaged immune defense mechanisms. In this context, it should be borne in mind the probability of increasing sporadic morbidity of toxoplasmosis against the background of widespread asymptomatic carriage (endemicity) due to the increasing use of corticosteroids, cytostatics, radiotherapy, leading to immunosuppression.
Lung surgery in children
Authors: Rokytsky M. R. , Akinfiev A. V. , Grebnev P. N. , Khabibullina R. V. , Poryvaeva V. N. , Molchanov N. N. , Volkova N. V. , Mikheev S. A. , Fattykhov Yu. I. , Zakomyrdin A. I. , Shagiakhmetova D. S.
Published: March 2022

The present report is the result of twenty years of research in the field of pediatric surgical pulmonology. During this period, over 3000 children with acute and chronic surgical lung diseases were treated in the hospital, 9785 bronchoscopies and over 2000 bronchographies were performed, 1473 radical lung operations and over 500 temporary bronchial occlusions were performed.
Phenolemia in diabetes mellitus
Authors: Talantov V. V. , Sultanova L. M. , Soldatov V. Yu.
Published: March 2022

We examined 96 patients (38 men and 58 women) with diabetes mellitus aged 16 to 54 years. 45 patients with type II diabetes did not receive insulin therapy, 52 patients with type I diabetes were treated with insulin. Patients underwent comprehensive clinical and laboratory examination in the period of compensation, subcompensation, decompensation and in the state of ketosis. Phenol in blood serum was determined by coulometric method.
Cholesterol loading test for diagnosing atherosclerosis with normolipoproteinemia
Authors: Guzachev A. A. , Rabinovich P. D.
Published: March 2022

Clinical observations suggest that coronary atherosclerosis may develop against the background of normal blood lipid content - normolipoproteinemia. As a diagnostic method of atherosclerosis with normolipoproteinemia the authors suggest using fat load and determination of the activity of hydrolytic liver enzymes using antipyrine test. They revealed in such patients reduced fat tolerance and decreased activity of liver hydroxylases. However, these tests are insufficiently selective, since fat load cannot reflect cholesterol metabolism abnormalities, and the antipyrine test cannot determine cholesterol hydroxylase (CH) activity, since the latter are highly specific for the substrate.
About treatment of chronic paraproctitis
Authors: Salikhov I. A. , Bolshakov A. I. , Kolomensky S. N. , Arzhanov Yu. V. , Gilmutdinov A. A. , Karpov A. V. , Starkov N. K.
Published: March 2022

Chronic paraproctitis is a consequence of poorly treated acute paraproctitis and is characterized by an internal rectal opening, a fistulous passage with perifocal inflammatory and scarring changes in the intestinal wall and pelvic cage spaces, and an external opening on the perineal skin. It is a rather common disease and occurs, according to literature sources and our data, in 15% of patients with rectal pathology. In our experience, there is no downward trend in the incidence of the disease.
Circulatory changes in the extra-orginal vessels of the ovaries after removal of the uterus without appendages
Authors: Kapeliushnik N. L. , Volodin S. K.
Published: March 2022

Disorders of hemodynamics as a result of damage or disconnection of vessels supplying the glands have a dramatic effect on their condition. Disorders of ovarian blood supply can also occur after surgical interventions. After amputation of the uterus without appendages some patients often have severe postoperative complications in the form of menopausal syndromes, while others do not. These changes are associated not only with the removal of the hormone, the endometrium, but also with a lack of local circulation, requiring preservation of the anastomosis between the uterine and ovarian arteries.
Immunoglobulin content in the blood of pregnant women and the fetus, breast milk during the adaptation of women to the adverse factors of the working environment
Authors: Pigalov A. P. , Dobronetsky V. S.
Published: March 2022

We aimed to specify the effect of the duration of a woman's industrial contact with the complex of saturated and unsaturated hydrocarbons at the level of their maximum permissible concentrations on the content of immunoglobulins A, M, G in the blood serum in early pregnancy, in the umbilical cord blood and breast milk in the first week after delivery.
Study of antiacidotic activity of dimefosfon
Authors: Studentova I. A. , Zaikonnikova I. V. , Vizel A. O. , Garaev R. S.
Published: March 2022

Acidotic shift of acid-base status is an important pathogenetic link in many diseases. Its urgent correction in urgent patients is usually carried out by intravenous administration of sodium bicarbonate or trisamine, chemically neutralizing excess acidic blood metabolites. However, these drugs do not eliminate intracellular pH shifts, do not affect the metabolic processes in the tissues that caused acidosis. They can be used only under hospital conditions under constant monitoring of acid-base status, requiring the use of special equipment.
Cationic proteins of leukocytes in peripheral blood of patients with brucellosis
Authors: Bukin V. N. , Tolokonskaya N. P.
Published: March 2022

According to a number of authors, a highly informative way to assess the state of non-specific resistance is to determine the content of non-enzymatic cationic proteins (NPCs) of neutrophil granulocytes of peripheral blood. Non-enzyme cationic proteins, in addition to their participation in the preparation of bacteria for phagocytosis, also serve as mediators of the inflammatory reaction.We set a goal to identify the possibility of using the indices of non-enzymatic cationic proteins of leukocytes in patients with brucellosis to assess the severity of the disease and to predict its outcomes.
Gastric secretory function in patients with hemorrhagic fever with renal syndrome
Authors: Shirapova M. S.
Published: March 2022

The aim of this work was to study secretory (acid-forming and proteolytic) functions of the stomach in patients and recovering patients with hemorrhagic fever with renal syndrome (HFRS).Seventy-six relapsed HFRS patients under 50 years of age without concomitant or past gastrointestinal diseases were examined. Dynamic follow-up was performed in the same patients. Diagnosis in all patients was confirmed serologically (4-fold increase of antibody titers by MFA method in dynamic examination of sera). The control group consisted of 26 healthy individuals.
Enterobiasis in children
Authors: Rizvanova M. A.
Published: March 2022

In 1987, 4171 children were examined for possible enterobiasis. Children referred by polyclinic physicians had the following signs of suspected disease: 42.5% had abdominal pain, 20% had anal itching, 12.5% had vascular dystonia, 1% had eosinophilia, and 1% had vulvovaginitis; 23% of the children had no complaints. The method of tape scraping from the perianal folds, which provides more complete detection of infestation, detected pinworm eggs in 346 (8.3%) children. In the family centers of enterobiasis 623 adults were examined; 4.9% of them were diagnosed with enterobiasis, 348 children were contacted, among them 8.6% of the children were infected.
Stromal morphogenesis and metastasis of malignant tumors
Authors: Petrov V. B.
Published: March 2022

The influence of the volume and character of stroma, microcirculatory channel and lymphoid infiltration on the metastasis of cancerous tumors was studied. We studied 340 cancerous tumors of the stomach, breast, lung and colon; morphostereometric analysis was carried out; histological, histochemical, histoenzymological and ultrastructural methods were used.
Research by the Department of Otorhinolaryngology on the problem of hearing loss
Authors: Svatko L. G.
Published: March 2022

The struggle for the prevention of hearing lesions, early detection and treatment of ear diseases are urgent problems of both domestic otorhinolaryngology and medicine in general. The introduction of new diagnostic methods and effective treatments have led to a significant decrease in the frequency of inflammatory ear diseases. At the same time, a number of factors contribute to the prevalence and growth of hearing loss among the population - influenza epidemics, the increasing impact of noise and vibration due to the mechanization of industrial and agricultural production, transport, the use of aminoglycoside antibiotics, etc. The increase in life expectancy also increases the number of hearing loss due to the development of presbyacusis in old age. The results of mass examinations of the population showed that 6% of the population has a hearing organ pathology. These circumstances dictate the need for further development and improvement of surdological care.
Epidemic mumps among students
Authors: Zayats N. A. , Drankin D. I. , Krylov B. A.
Published: March 2022

The purpose of this work was to study the spread of epidemic parotitis among students of 9-10th grades of secondary schools and vocational schools. Analysis of data on morbidity in Saratov from 1979 to 1983 showed a relatively high morbidity of epidemic mumps among the general population and students of schools and vocational schools in particular. The situation changed dramatically after 1984, when the morbidity rate among the general population decreased sharply, and cases of parotitis among students of vocational schools and senior high schools became sporadic, in some years not observed at all. There is reason to believe that these changes in the morbidity rate were the result of mass immunization against mumps in the most susceptible age groups of the population.
Non-specific and specific neutrophil adhesion in the pathogenesis and clinic of rheumatoid arthritis
Authors: Fomina L. L. , Salikhov I. G. , Mayansky A. N. , Chebotar I. V.
Published: March 2022

We set out to study the specific adhesion of polymorphonuclear leukocytes (PMNL) mediated by immunoglobulin G and complement СЗ-component (as the most frequent components of tissue immune deposits in rheumatoid arthritis), To specify clinical informativity of the test of non-specific adhesion of neutrophils and to clarify the character of the influence of circulating immune complexes (CIC) and rheumatoid factor (RF) on the course of adhesive reactions.
Differential X-ray Diagnosis of Bone and Joint Diseases. 1988. Tatar Book Publishing House. Circulation 3000 copies. 170 p.
Authors: Fastykovskaya E. D.
Published: March 2022

The monograph is written on a topical topic. Practical radiologists experience great difficulties in diagnosing diseases of bones and joints. This can be explained by the complexity of the perception of X-ray semiotics of diseases and therefore there is a great need for this kind of monographs. X-ray diagnosis of diseases of bones and joints needs to be generalized and popularized. The book is written for radiologists, oncologists, traumatologists, and orthopedists and consists of five chapters addressing private pathology.
Paradontal nidus and consequences of its elimination
Authors: Goryachev N. A.
Published: March 2022

The role of dental foci of chronic infection is well known. The majority of works are devoted to tonsillar and dental (periapical) foci. Although the focus of chronic inflammation in the periodontium is considered to be well-drained, modern periodontologists believe that it has exceptional pathogenicity. Currently, the connection between the pathogenic action of periodontal disease and periodontal pockets has been revealed, and, as confirmed by us, regardless of the nosological affiliation of periodontal disease. Thus, comparing the indices of immunobiological state of the body (the activity of lysozyme of mixed and parotid saliva, blood serum, the concentration in blood of serum immunoglobulins G, A and M, the level of circulating immune complexes (CIC) and the frequency of microbial sensitization) in patients with chronic gingivitis, periodontitis and periodontitis we found significant changes in these indicators only in patients burdened with periodontal pockets.
Absorptive function of the colon in diphyllobothriosis
Authors: Babichenko O. E.
Published: March 2022

Absorption in the gastrointestinal tract is a very important biological process by which the body is provided with the necessary nutrients. Absorption reflects the specificity of metabolism, depends on the course of physiological processes and is regulated by neurohumoral factors. Digestion occurs mainly in the small intestine. It is carried out with the participation of a number of enzymes produced by the pancreas, intestine, and liver.
To the problem of carcinogenicity in the oil and petrochemical industry
Authors: Gimadeev M. M.
Published: March 2022

Under the conditions of the modern scientific and technological revolution, the rapid development of industry, transport, agriculture, growth and development of cities is often accompanied by changes in the natural environment towards its deterioration. This is evidenced by the data characterizing the state of the environment in many cities of our country. In some industrial centers and cities, despite the measures taken in recent years, the environment continues to be polluted by emissions from various enterprises, thermal power plants, transport. Of particular concern is the harmful effect of various environmental factors on the health of the population and their living conditions.
Development of clinical gastroenterology in Kazan Medical Institute
Authors: Bilich I. L. , Shigabutdinova F. G.
Published: March 2022

The range of traditional problems of the oldest university of our country - Kazan Medical Institute - includes problems of physiology and pathology of digestive organs. The founders of clinical gastroenterology are widely known in our country Professors S. S. Zimnitsky (the pupil of S. P. Botkin and I. P. Pavlov), M. N. Cheboksarov, A. L. Luria. In 1936 Prof. S.S. Zimnitsky published a monograph "On disorders of secretory activity of gastric glands in terms of functional diagnostics" (clinical lectures for students and doctors). In another work he expounded the original acid "sour" theory of the pathogenesis of gastric ulcers. At about the same time Prof. M. N. Cheboksarov published a work on pyloroduodenitis ("On peptic ulcer without ulcer") and A. L. Luria described irritable stomach syndrome (preulcer phase of the disease).
Assessment of life satisfaction and impact of work on personal life among heads of clinical departments
Authors: Yarotsky S. Yu. , Sandakov Ya. P. , Kochubey A. V. , Kochubey V. V.
Published: March 2022

Objective. To study life satisfaction and the impact of work on personal life among heads of clinical departments.

Materials and methods. A correspondence survey of 216 heads of clinical departments was conducted using standardized questionnaires with the calculation of the life satisfaction index and the indices of interaction between work and personal life. The average age of the respondents was 47.9 8.08 years; the average length of service was 23.1 8.60 years.

Results. The average life satisfaction index is 6.0 0.951. There is a weak inverse correlation of the index with age r = 0.2; p = 0.004 and length of service r = 0.2; p = 0.001. The values of the life satisfaction index do not depend on gender (t = 0.23, p = 0.818), place of work (t = 0.14; p = 0.886), availability of qualification category (t = 0.36; p = 0.722), academic degree (t = 1.8; p = 0.073), second higher education (t = 1.67; p = 0.097), work in "red zone" (t˂0,001; p = 1,000). The average index of negative interference of work in personal life is 1.59 0.474 and personal life in work is 1.04 0.123, positive influence of work on personal life is 2.64 0.897 and personal life on work is 3.35 0.882. There is a significant difference in the index of negative interference of personal life in work by respondents of different sexes (t = 3.24; p = 0.001) who worked in hospitals (t = 3.14; p = 0.002) and in the "red zone" (t = 3.29; p = 0.01). There is a negative weak correlation between the life satisfaction index and the index of the positive impact of personal life on work (r = 0.34; p˂0,001) and work on personal life (r = 0.37; p˂0,001).

Conclusions. The life satisfaction index of department heads is high 6.0 out of 7. However, a decrease in the ratings of the positive interaction of work and personal life with an increase in the satisfaction index dictates the need to continue research.
Formulasi Kapa dan Iota Karagenan dalam Pembuatan Produk Kosmetik Pelembap Bibir
Authors: Sujuliyani Sujuliyani , Pebriyanti Puspa , H. Sipahutar Yuliati
Published: March 2022

Kapa dan iota karagenan memiliki sifat fungsional sebagai humektan yang dapat mempertahankan kelembapan bibir pada produk kosmetik pelembap bibir (lip balm). Karagenan digunakan sebagai bahan alami yang lebih aman dan mengurangi komposisi bahan kimia dalam formulasi pelembap bibir. Tujuan penelitian ini untuk menentukan formulasi yang terbaik dari kombinasi kapa dan iota karagenan dalam menghasilkan pelembap bibir yang sesuai standar. Perlakuan penambahan kapa dan iota karagenan pada produk pelembap bibir terdiri dari produk tanpa penambahan kapa dan iota karagenan, 1:1, 1:2, 2:1 dan 1:3. Data sensori menggunakan uji Kruskal-Wallis dilanjutkan dengan pembandingan ganda. Parameter mutu yang diuji yaitu pH dan LoD. Hasil penelitian menunjukkan pH produk pelembap bibir dengan perlakuan 1:1, 1:2, 2:1 dan 1:3 secara berurutan sebesar 5,70; 5,65; 5,55; 5,75 dan pengujian LoD (%) dengan perlakuan 1:1, 1:2, 2:1 dan 1:3 secara berurutan sebesar 2,09; 1,05; 0,98: 1,01; 0,96. Perbandingan kapa dan iota karagenan terbaik adalah 1:3. Berdasarkan hasil data sensori dan karakteristik mutu, pelembap bibir 1:3 memiliki kenampakan, warna, dan tekstur yang menarik bagi panelis, serta memiliki berat penyusutan yang paling rendah dan mampu menahan kelembapan dalam jangka waktu yang paling lama.
Integrasi Sentrifugasi Suhu Rendah dengan Optimasi Ekstraksi Enzimatis Minyak Mata Tuna menggunakan Response Surface Methodology
Authors: Trilaksani Wini , Riyanto Bambang , Nurhayati Tati , Santoso Joko , Kurniawan Ikram Abi Hamzah
Published: March 2022

Mata tuna yang kaya akan asam lemak omega-3 eicosapentaenoic acid dan docosahexaenoic acid dapat diperoleh dengan ekstraksi suhu rendah tetapi rendemen yang diperoleh belum maksimal. Nilai rendemen minyak mata tuna dapat ditingkatkan dengan hidrolisis enzimatis. Response surface methodology (RSM) dapat membantu menganalisis pengaruh faktor-faktor terhadap respon untuk mengoptimalkan kondisi hidrolisis enzimatis. Tujuan penelitian ini adalah maksimalisasi rendemen minyak, menentukan kondisi optimum ekstraksi enzimatis minyak mata tuna dengan faktor konsentrasi papain dan waktu hidrolisis yang berbeda menggunakan permodelan central composite design-face centered (CCDFC) pada RSM, dan determinasi karakteristik minyak. Kondisi hasil validasi optimum hidrolisis enzimatis minyak mata tuna menghasilkan nilai rendemen 11,24±0,09% pada konsentrasi 1,02% enzim papain selama 3 jam. Kandungan EPA dan DHA minyak mata tuna pada kondisi optimum tergolong sangat tinggi yaitu 6,02% EPA dan 30,30% DHA dari 99,90% total asam lemak yang teridentifikasi.