bluuebunny/crossref_metadata_2025 huggingface dataset:
Tinjauan Awal Bangunan Rumah Tinggal Kolonial Kawasan Simpang Surabaya
Authors: Bayu Murti Delta
Published: July 2019

Tujuan studi ini membahas keberadaan bangunan rumah tinggal kolonial Belanda yang ada di kawasan Simpang Surabaya. Metode pengumpulan data dalam studi ini adalah survei arkeologis, melalui pengamatan, yang didokumentasi bergaya arsitektur sebelum 1900, arsitektur transisi, dan arsitektur modern. Selain itu didokumentasi pula kerusakan dan perubahan pada bangunan rumah tinggal kolonial yang ada, yang terindikasi berkaitan dengan statusnya sebagai bukan cagar budaya dan perkembangan kawasan Simpang sendiri.
Peraturan Presiden Nomor 58 Tahun 2014 tentang Rencana Tata Ruang Wilayah Kawasan Strategis Nasional Borobudur dan Sekitarnya sebagai Payung Hukum Konservasi Kawasan Cagar Budaya Borobudur
Authors: Sularsih Sri
Published: July 2019

Pemanfaatan ruang di Kawasan Borobudur membutuhkan perhatian lebih oleh Pemerintah maupun Pemerintah Daerah. Maraknya pembangunan tak berizin di sekitar kawasan terutama sepanjang Koridor Palbapang yang semakin lama semakin tidak terkendali, jika tidak dilakukan pemantauan dan evaluasi serta tindak lanjut maka akan semakin menjauhkan angan dalam rangka mewujudkan suatu kawasan cagar budaya yang lestari dan berkelanjutan. Masih lemahnya penegakan peraturan dan minimnya pemahaman masyarakat terkait Kawasan Borobudur menjadi faktor semakin meningkatnya pemanfaatan lahan yang perlu segera untuk dilakukan pengendalian. Diterbitkannya Peraturan Presiden Nomor 58 Tahun 2014 tentang Rencana Tata Ruang dan Wilayah Kawasan Strategis Nasional Borobudur dan Sekitarnya menjadi langkah nyata dalam pengendalian pemanfaatan ruang di Kawasan Borobudur. Kondisi pemanfaatan ruang yang ada saat ini perlu dikaji lebih lanjut dengan penegakan aturan yang semestinya.
Pengaruh Konsentrasi Larutan dan Durasi Perendaman terhadap Efektivitas Bahan Konservan Poly Etilen Glikol dalam Pelestarian Cagar Budaya Material Kayu
Authors: Suranto Yustinus
Published: July 2019

Indonesia memiliki kekayaan cagar budaya berbahan kayu maritim yang sangat besar. Upaya pelestarian dilakukan dengan secara murni dan diterapkan pada perahu kuna Punjulharjo. Keberadaan PEG yang terbatas dan harganya yang mahal mendorong pencarian bahan konservan lain yang banyak tersedia dan murah harganya. Penelitian ini bertujuan mengetahui pengaruh komposisi campuran urea dan PEG sebagai bahan konservan dan durasi perendaman terhadap efektivitas konservasi kayu waru gunung. Efektivitas konservasi diukur berdasarkan parameter stabilitas dimensi kayu. Penelitian dilakukan dengan prosedur berikut. Empat kelompok contoh uji disediakan, yakni satu kelompok kontrol dan tiga kelompok perlakuan. Disediakan tiga macam konservan campuran urea dan PEG 1000 dengan proporsi 10 dan 10 gram (larutan A1), 20 dan 10 gram (larutan A2), serta 30 dan 10 gram (larutan A3). Kelompok contoh uji direndam dalam larutan konservan dengan durasi perendaman masing-masing 1, 3 dan 5 hari. Penyusutan tangensial, radial, ASE tangensial, ASE radial, jumlah retak, dan panjang retak diukur. Data dianalisis dengan rancangan acak lengkap disusun faktorial dan analisis lanjutan dengan metode beda nyata terkecil. Hasil penelitian memperlihatkan bahwa proporsi bahan konservan mempengaruhi penyusutan tangensial, penyusutan radial, ASE tangensial dan ASE\ radial. Semakin tinggi proporsi urea dalam bahan konservan semakin rendah penyusutan tangensial dan penyusutan radial, dan semakin tinggi nilai ASE tangensial dan ASE radial. Lama perendaman kayu dalam konservan mempengaruhi penyusutan tangensial. Semakin lama durasi perendaman semakin rendah penyusutan tangensial. Interaksi antara proporsi bahan konservan dan durasi perendaman berpengaruh terhadap penyusutan radial dan nilai ASE radial.
Pengaruh Kecepatan Putar Terhadap Hasil Coran pada Metode Pengecoran Sentrifugal dalam Pembuatan Produk Pisau Pakan Ternak dengan Material Ni-Hard1
Authors: Kusnowo Roni , Hanaldi Kus
Published: July 2019

Animal feed knife is a tool that serves to cut and chop animal feed consisting of grass as the main ingredient with additives such as bran, herbs, centrate, cassava, tofu pulp and others. Therefore, as a cutting tool must have the properties of friction resistance, impact resistance, and have good sharpness, so that the material chosen is Ni-Hard 1. The use of centrifugal casting method was chosen because it has the advantage of being able to make castings with relatively thin thickness this is due to the influence of the centrifugal force on the distribution of metal liquids throughout the cavity in the mold. Case study in this study is the use of centrifugal casting methods as an alternative to gravity casting methods to overcome defects of misruns. This research was conducted to investigate the effect of speed on the formation of castings products. The method that was carried out began with a literature study on centrifugal casting, and continued by determining the material, the temperature of the cast is in the range 1250ºC - 1300ºC, and the type of mold. The next step is to do work drawings, pattern making, mold making, casting processes, fettling processes, and analysis. With variations in speed of 200 rpm, 300 rpm and 400 rpm, it can be seen the optimal speed for making this product. The results of this study obtained optimal speed at a speed of 300 rpm to make good quality of animal feed knife products.
PERANCANGAN MOBILE CATALOGUE KERAJINAN KHAS DAERAH SUMATERA SELATAN
Authors: Sahfitri Vivi
Published: July 2019

South Sumatera is one of the provinces in Indonesia that has its own distinctive characteristic especially in the local handicrafts that become an attraction for tourists who visit this region. South Sumatra consists of several district and city areas that have their own distinctive and cultural characteristics. South Sumatera area is quite spacious with a variety of different tourist attractions in each region, requiring a media information that can reach the community widely and as a medium of tourism promotion in the province of South Sumatera. One of the wealth owned by South Sumatera Province is a variety of typical handicrafts from various regions in South Sumatera. The research resulted in the design of the application catalog typical South Sumatera mobile based Android. Mobile Catalogue Typical Crafts South Sumatera will provide information about the share of South Sumatera handicrafts such as songket, batik, jumputan cloth, blongsong cloth, tanjung cloth, and crafts carving typical Palembang.
PENELITIAN TINDAKAN (Action Research) TENTANG KOMUNIKASI AGAMA DI GRIYA LOBUNTA LESTARI CIREBON
Authors: . Mahmudah
Published: July 2019

ABSTRAKDalam rangka menciptakan masyarakat yang sakinah, maka perlu adanyapembinaan-pembinaan pada masyarakatnya, melalui pendidikan dan pembinaankeluarga, baik yang menyasar pada bapak, ibu maupun anak-anaknya.Penelitianini memfokuskan pada tindakan tentang komunikasi agama dan efektifitas daritindakan tersebut. Untuk menjawabnya digunakan teori tindakan Max Weber.Purposive adalah teknik yang digunakan untuk menentukan informan. Penelitianini dilakukan dengan cara deskriptif kualitatif dan memilih lokasi di GriyaLobunta Lestari Cirebon. Teknik pengumpulan data dilakukan dengan wawancaramendalam yang kemudian dianalisis secara reduksi.Berdasarkan penelitianditemukan jawaban. Belajar membaca Al qur’an dengan benar dan memahamisekaligus mengamalkan agama Islam, dipahami sebagai suatu kewajiban bagisetiap muslim baik laki-laki maupun perempuan. Motif melakukan kegiatanmembaca Al qur’an sekaligus mengamalkan kandungannya, memberikankenyamanan batin, merasakan kedekatan kepada Allah, serta menumbuhkanikatan silaturarahmi terhadap sesama muslim. Prilaku informan setelah mengikutikegiatan tersebut semakin menunjukkan perubahan yang sangat signifikan dalamkehidupannya,yakni semakin membaik. Keefektifan kegiatan , baik yangberhubungan dengan kegiatan pemberantasan buta huruf Al qur’an maupun kajiankitab, sudah terbilang efektif, hanya saja perlu kiranya ditambah frekwensipertemuan dalam kegiatan tersebut.Kata Kunci : Penelitian Tindakan, Komunikasi Agama, Griya LobuntaAbstractIn order to create a sakinah community, it is necessary to provide guidance to thecommunity, through education and family development, both targeting the father,mother and children. This research focuses on actions on religious communicationand the effectiveness of the action. To answer it is used the theory of action MaxWeber. Purposive is a technique used to determine informants. This research wasconducted by qualitative descriptive method and chose the location at GriyaLobunta Lestari Cirebon. Technique of data collecting is done by depth interview40which then analyzed by reduction. Based on research found answer. Learning toread Al Quran correctly and understand as well as practice Islam, understood asan obligation for every Muslim both men and women. The motive to read AlQur'an activities at the same time mengamalkan content, providing comfort,feeling the closeness to God, and foster bonds to the fellow Muslim silaturarahmi.The behavior of informants after participating in these activities has shown a verysignificant change in their lives, which is getting better. The effectiveness ofactivities, both related to the illiteracy of Al Quran and the study of books, hasbeen effective, it is only necessary to increase the frequency of meetings in theactivity.Keywords: Action Research, Religious Communication, Griya Lobunta
PROSES WORD OF MOUTH COMMUNICATIONS SEBAGAI MEDIA PROMOSI UNIVERSITAS SWADAYA GUNUNG JATI CIREBON
Authors: Lestari Aghnia Dian , Erawati Dedet
Published: July 2019

ABSTRAK Isu-isu dibicarakan, dikendalikan dan diarahkan dan berputar cepat baik sengaja atau tidak untuk kepentingan kebutuhan intitusi atau lembaga. Tujuan penelitian ini untuk mengetahui proses word of mouth, hambatan ketika mempromosikan, dan peran media sosial sebagai media promosi UGJ dalam kegiatan penerimaan mahasiswa baru. Diperlukan kreativitas, fleksibilitas, dan sikap bijaksana menggunakan komunikasi ini agar masyarakat membicarakannya dengan jujur agar memiliki pengaruh positif, meski terkadang tidak terprediksinya informasi oleh pihak eksternal melalui media sosial dalam jejaring internet seperti Whatsapp, Instagram, Facebook, Website maupun secara langsung karena ada pihak yang merasa tidak puas dengan hasil yang dirasakan. Sesuai dengan hasil penelitian ini, menunjukkan bahwa lebih mudah menyerap informasi tentang UGJ dari apa yang didengarnya. Terlebih lagi informasi tersebut atas saran dari kerabat, keluarga, alumni bahkan sampai mahasiswa turut terlibat dalam penyebaran informasi penerimaan mahasiswa baru. Promosi UGJ yang dilakukan dengan word of mouth memang lebih efektif dibanding media sosial, seperti Website, Instagram, Facebook karena lebih mudah untuk menangkap respon lawan bicara dibandingkan informasi dari Website yang pesannya hanya satu arah. Lebih mudah untuk mengendalikan informasi negatif, berita simpang siur atau salah informasi pada saat face to face karena dapat dikendalikan secara langsung pada saat itu. Metode penelitian ini adalah metode kualitatif melalui studi deskriptif. Teknik pengumpulan data dengan observasi, studi kepustakaan, dan wawancara. Temuan penelitian ini menghasilkan model word of mouth UGJ sebagai media promosi khususnya dalam menggaet mahasiswa baru sehingga kelak bermanfaat untuk UGJ dalam menyusun strategi agar terhindar dari isu-isu buruk dan mempertahankan isu-isu yang baik. Kata Kunci: word of mouth communication, promosi, universitas swadaya gunung jati
ANALISIS SEMIOTIK TERHADAP IKLAN SAMPOERNA A MILD HIJAU EDISI DATENG KONDANGAN
Authors: Wicaksono Sony
Published: July 2019

AbstrakIklan adalah sarana komunikasi persuasif yang bertujuan mempengaruhi masyarakat untuk menggunakan jasaatau barang. Oleh karenanya, diperlukan sebuah iklan efektif untuk mampu meyakinkan dan mempersuasikhalayak. Peneliti memfokuskan pada iklan rokok Sampoerna A Mild Hijau karena merupakan salah satu produkyang terkenal dan terkemuka di Indonesia. Dalam iklan Sampoerna A Mild Hijau edisi Dateng Kondangan,terdapat beberapa simbol atau tanda yang disampaikan secara tersirat melalui teks, audio, maupun visualyang didalamnya sebenarnya melibatkan brand atau kompetitor lain. Tujuan dari penelitian ini adalah untukmelihat pemaknaan simbol-simbol iklan Sampoerna Hijau versi “Dateng Kondangan” dalam kajian semiotika.Penelitian ini menggunakan pendekatan kualitatif. Metode penelitian yang digunakan adalah metode analisis semiotik model Roland Barthes. Lewat model Roland Barthes, peneliti mampu mengungkap makna denotasi, konotasi, dan mitos. Penelitian ini menemukan data bahwa iklan tersebut menggambarkan persainganproduk rokok di Indonesia yang diwakili oleh brand kompetitor dimana asosiasi warna merah (Gudang GaramMerah), warna coklat (Djarum Coklat), dan hijau (Sampoerna Hijau).Kata Kunci : Semiotika, Iklan Sampoerna, IklanAbstractsAdvertising is the medium of  persuasive communication that aims to influence people to use services or goods. Therefore, an effective advertisement is required to be able to convince and persuade audiences.The researcher focused on Sampoerna A Mild Green cigarette advertisement because it is one of the famousand leading products in Indonesia. There are brand competitor’s symbols and signs that implicitly projectedthroughout the text, audio and visual contents.The aim of this research is to depict the symbols’s meanings ofthis advertisement. This research uses qualitative approach. The research method used is semiotic analysismethod of Roland Barthes model. Through the model Roland Barthes, researchers are able to uncover themeaning of denotation, connotation, and myth. This research finds the data that the advertisement describescompetition of cigarette product in Indonesia represented by competitor brand where red color association (Gudang Garam Merah), brown color (Djarum Coklat), and green (Sampoerna Hijau).Keywords: Semiotics, Sampoerna Advertisement, Advertisement
The Relation Between Infrastructure Quality and Government Effectiveness in Egypt.
Authors: Elnemr Mustafa
Published: July 2019

The article examines the relationship between infrastructure quality and government effectiveness in Egypt. The hypothesis is that public private partnership can help Egypt increase its infrastructure efficiency and lower burden in government budget.

The paper conclude that Egypt have a considerable opportunity to finance its infrastructure investment gap through private investment. Public-Private partnership could be adopted as it provides the fastest gains in efficiency.
Market Theory and Capitalist Axiomatics
Authors: Holland Eugene
Published: July 2019

Producing a properly philosophical theory of capitalism as an open axiomatic system requires adding intensive multiplicities to the mathematical account of set theory, which allows only extensive multiplicities. Doing so enables us to understand pricing as a process of transforming intensive quantities into metric quantities, and thereby develop a diagram of the dynamics of axiomatisation and of the market as the two-sided and asymmetrical recording surface of the capitalist socius whose slope represents the infinite debt owed to finance capital. The capitalist market axiomatises four kinds of flows – flows of liquid capital and abstract labour, of course, but also flows of raw materials and energy and of human populations. At the same time that axiomatisation conjugates these flows in denumerable sets to extract surplus-value, it connects flows in minor, non-denumerable sets that escape axiomatisation and may become revolutionary. Such minor connections would constitute the fabric of a post-capitalist axiomatics.
Reworking Testosterone as a Man's Hormone: Non-binary People using Testosterone within a Binary Gender System
Authors: Bolton Rillark M.
Published: July 2019

Testosterone, deemed the ‘male hormone’, is a central method used by transgender men to enact gendered bodily changes. Testosterone is framed as a means for transgender men to align their external ‘female’ bodies with their internal male genders because it is positioned by medical and social logics as a kind of distilled masculinity. While recognising both the ways that trans men always already subvert and usurp these logics, the coherence of these logics is further undercut when assigned female at birth non-binary people, who do not feel themselves to be men, are, in increasing numbers, using exogenous testosterone. Using qualitative interviews with seven non-binary people, this article grapples with the desire of these participants to use testosterone, without being tied to masculinity, maleness or men. In this article, I first focus on how these participants re-formed testosterone as a substance that can unmake, rather than confirm gender. Secondly, I look at how their use of testosterone rejects the centrality of an alignment between an internal gender and an external body. And finally, in turning to the process of ‘coming out as a testosterone user’ I explore how one participant asserted themselves not as a concrete and clear identity, but rather as a self in action. All three negotiations point to new logics of what testosterone is and could be, how it arises and moves with gender, and how these selves may begin to exist in new and novel ways.
Representing Transgender Embodiment in Film and Culture: Looking beyond the Transition Narrative in Amazon's Transparent
Authors: Seymour Natasha
Published: July 2019

In this article, I identify how the Amazon television series Transparent deploys narrative thematics of home, belonging and importantly, a journey to becoming, to stage a limited representation of transgender lives within a heterosexual economy. Transgender studies has long been preoccupied with the transition narrative as a primary tool of representation, it is a vehicle through which the disjointedness of gender transition can be reformed into a narrative that enables intelligibility and fosters a sense of belonging. I argue however that the transition narrative, which aims to make transgender lives visible (and consumable) to an audience of trans and non-trans folk, is limiting in its representational scope and may impede, rather than mobilise, this agenda. The transition narrative constructs transgender lives within normative frames of time and place, and in the codes of textual conventions that compulsively render transgender transition into narrative. In Transparent, the themes of home and belonging are used to lend a sense of cohesion to the experience of transition in ways that implicate the representation of its trans characters in a ‘universalising narrative of liberal democratic progress’ ( Keegan 2013 ). I will examine the various ways this text employs the conventions of narrative and in doing so, fails to confront its audience with the daily cultural and social transgressions that make up the lived experiences of transition.
Dört Tarafından Ankastre Mesnetli Berkitmesiz Dikdörtgen Narin Levhaların Farklı Kalınlık Ve Boyutlarda Karşılıklı Kenarlarından Düzgün Yayılı Yükle Yüklenmemesi Durumunda Taşıma Davranışının Belirlenmesi
Authors: Yelgin Ahmet Necati , Yelgin Hüseyin , Özmen Akın , Külekçi Uğur
Published: July 2019

Square sheet with outer edges clamped or simply supported are widely in use in aircraft engineering and ship industry. These types of supporting systems are applied as a body structure in airplanes. In case of loading these elements with distributed compressive load from opposite ends, an unstable buckling problem is faced. In this study, (1 mm, 3 mm, 4 mm) thickness sheets with 1 were experimental tested. The results showed the sensitivity of these systems to buckling problem.
Design and Development of Unmanned Hovercraft
Authors: Ganesan Surendar , Esakki Balasubramanian
Published: July 2019

The present study focuses on the development and performance analysis of unmanned hovercraft. The inherent characteristics of hovercraft such as hovering and gliding on diverse surfaces like water and land are intended for pollution control in remote water bodies. The vehicle is designed with bag skirt configuration for ease and smooth functioning on multiple terrains. Computer Aided Design (CAD) model with incorporation of spraying mechanism as a payload is conceptualized. Computational Fluid Dynamic (CFD) analysis at internal flow condition is performed and bag pressure of the skirt is assessed. The prototype model of vehicle to accommodate a payload of 0.8kg is fabricated from suitable lightweight materials and the experiments are conducted to explore the desired operation of hovering and forward thrust systems. The performance studies are made with velocity component in linear direction on land and water surfaces.
Geodesic Approach for an Efficient Trajectory Planning of Mobile Robot Manipulators
Authors: Sahu Pradip Kumar , Biswal Bibhuti Bhusan
Published: July 2019

In this paper, the geodesic approach has been employed for an effective, optimal, accurate and smooth trajectory planning of a mobile robot manipulator mechanism. Generally, geodesic can be described as the shortest curvature between two loci on a Riemannian manifold. In order to attain the planned end-effector motion, Riemannian metrics has been consigned to the forward kinematics of mobile robot wheel as well as the mobile robot manipulator workspace. The rotational angles of wheel and joint kinematic parameters are chosen as local coordinates of spaces to represent Cartesian trajectories for mobile wheel rotation trajectories and joint trajectories respectively. The geodesic equalities for a given set of boundary conditions are evaluated for the chosen Riemannian metrics and the computational results of the geodesic equations have been shown. So as to verify and validate the efficiency of the chosen geodesic scheme, the method has been implemented for the motion planning and optimization of a mobile robot with a simple 3R manipulator installed upon its platform.
Terapia de Reorientación Adaptativa: Un modelo adleriano para el tratamiento de trastornos emocionales
Authors: Rasmussen Paul R
Published: July 2019

Las emociones imperantes surgen en la vida de una persona como mecanismos adaptativos para ayudar al individuo a superar las tareas que presenta la vida. Cuando la orientación del Estilo de Vida propio se caracteriza por unas convicciones y una lógica privada sesgadas, esas emociones que nos empujan a la acción pueden predominar la vida y contribuyen a dificultades que se repiten y van empeorando, muchas de las cuales se diagnostican como trastornos clínicos reconocibles. El tratamiento adleriano, en lugar de centrarse específicamente en los síntomas, se centra en la orientación del Estilo de Vida que provoca esos síntomas. En estos casos se necesita una reorientación adaptativa hacia la vida más óptima. La Reorientación Adaptativa se centra en el estado deseado del individuo y lo ayuda a ajustar la orientación del Estilo de Vida de una manera más efectiva.
Clinical and Immunological Response in Dogs Naturally Infected by L. infantum Treated with a Nutritional Supplement
Authors: Lombardi Pietro , Palatucci Anna Teresa , Giovazzino Angela , Mastellone Vincenzo , Ruggiero Giuseppina , Rubino Valentina , Musco Nadia , Crupi Rosalia , Cutrignelli Monica Isabella , Britti Domenico , Vassalotti Giuseppe , Terrazzano Giuseppe , Cortese Laura
Published: July 2019

The use of nutraceuticals as immunomodulators in the treatment of visceral leishmaniasis has generated interest in the current approaches to treat the disease. In this clinical and immunological study, we investigated whether the administration of a nutritional supplement mediates the immune-modulatory response in canine leishmaniosis (CL) and improves the clinical outcome of the disease. With this purpose, we analysed T lymphocyte subsets in peripheral blood (PB) of 12 dogs naturally infected by Leishmania infantum, following treatment with a nutritional supplement. The regulatory T (Treg) cells and the T helper (Th) 1 population were specifically evaluated. The animals underwent complete clinical examination and blood sample collection for haematological, biochemical, serological and immunological analysis before treatment (T0), one month (T30) and 3 months (T90) after the onset of the nutraceutical supplementation. We observed that nutraceutical supplementation was associated with immunomodulation of Th1 response and significant clinical improvement of the animals. No side effects were observed. Therefore, a potential supportive role for the nutraceutical supplement during canine leishmaniasis is proposed.
Comparative Grain Yield, Straw Yield, Chemical Composition, Carbohydrate and Protein Fractions, In Vitro Digestibility and Rumen Degradability of Four Common Vetch Varieties Grown on the Qinghai-Tibetan Plateau
Authors: Huang Yafeng , Zhou Fangfang , Nan Zhibiao
Published: July 2019

Four varieties of common vetch, including three improved varieties (Lanjian No. 1, Lanjian No. 2, and Lanjian No. 3) and one local variety (333A), were evaluated for varietal variations in grain yield, straw yield and straw quality attributes on the Qinghai-Tibetan Plateau. Crops were harvested at pod maturity to determine grain yield, straw yield, harvest index, and potential utility index (PUI). Straw quality was determined by measuring chemical composition, carbohydrate and protein fractions, in vitro gas production and in situ ruminal degradability. Results showed a significant effect (p < 0.01) of variety on the grain yield [875.2–1255 kg dry matter (DM)/ha], straw yield (3154–5556 kg DM/ha), harvest index (15.6–28.7%) and PUI (53.3–63.2%). Variety also had a significant effect on chemical composition, carbohydrate and protein fractions (p < 0.05) except non-structural carbohydrates and rapidly degradable sugars. Significant differences (p < 0.05) were observed among the varieties in potential gas production [188–234 mL/g DM], in vitro organic matter (OM) digestibility (43.7–54.2% of OM), and metabolizable energy (6.40–7.92 MJ/kg DM) of straw. Significant differences (p < 0.001) were also observed among the varieties in rapidly degradable DM fraction and effective DM degradability of straw; however, no difference was observed in other DM degradation parameters and neutral detergent fiber degradation parameters. In conclusion, based on straw yield and quality, Lanjian No. 1 has the greatest potential among the tested varieties as a crop for supplementing ruminant diets for smallholder farmers on the Qinghai-Tibetan plateau.
Effects of Dietary Betaine on Growth Performance, Digestive Function, Carcass Traits, and Meat Quality in Indigenous Yellow-Feathered Broilers under Long-Term Heat Stress
Authors: Liu Wenchao , Yuan Yilin , Sun Chenyu , Balasubramanian Balamuralikrishnan , Zhao Zhihui , An Lilong
Published: July 2019

Heat stress has a profound effect on poultry health and productivity. The present study evaluated whether feeding betaine could ameliorate long-term heat stress-induced impairment of productive performance in indigenous yellow-feathered broilers. A total of 240 five-week-old male broilers were randomly allocated to five treatments with six replicates of eight broilers each. The five treatments included a thermoneutral zone control group (TN, fed basal diet), a heat stress control group (HS, fed basal diet), and an HS control group supplemented 500, 1000, 2000 mg/kg betaine, respectively. The TN group was raised at 26 ± 1 °C during the whole study, HS groups exposed to 32 ± 1 °C for 8 h/day from 9:00 am to 17:00 pm. The results showed that heat stress decreased the body weight gain (BWG) and feed intake of broilers during 1–5, 6–10, and 1–10 weeks (p < 0.05). Dietary betaine tended to improve the BWG and feed intake of broilers under 5 weeks of heat stress (linear, p < 0.10), and betaine supplementation linearly increased the BWG and feed intake during 6–10 and 1–10 weeks (p < 0.05). Additionally, nitrogen retention was reduced by 5 weeks and 10 weeks of heat stress (p < 0.05), whereas dietary betaine could improve nitrogen retention in heat stressed broilers after both 5 and 10 weeks of heat stress (linear, p < 0.05). Moreover, this study observed that the trypsin activity of jejunum was decreased by 5 weeks of heat stress (p < 0.05), whereas betaine supplementation had quadratic effects on trypsin activity of jejunum in heat stressed broilers (p < 0.05). Furthermore, 10 weeks of heat stress induced a reduction of villus height of the duodenum and jejunum (p < 0.05), and decreased the villus height to crypt depth ratio of the jejunum (p < 0.05). Supplementation with betaine ameliorated the adverse effects of heat stress on these parameters (p < 0.05). Compared with the TN group, 10 weeks of heat stress reduced carcass and breast yield (p < 0.05) and betaine supplementation improved carcass and breast yield of heat stressed broilers (linear, p < 0.05). In conclusion, dietary supplementation of betaine could reduce the detrimental effects of long-term heat stress on growth performance, digestive function, and carcass traits in indigenous yellow-feathered broilers.
Dog-Assisted Therapy and Dental Anxiety: A Pilot Study
Authors: Cruz-Fierro Norma , Vanegas-Farfano Minerva , González-Ramírez Mónica Teresa
Published: July 2019

Animal-assisted therapy aimed at improving individuals’ mental or physical health has been widely reported. However, the data on how a therapy dog could help control anxiety during dental procedures is scarce. The objective of this work was to evaluate the effect of dog-assisted therapy on people with a history of dental anxiety while receiving preventive dental treatment. Twelve adults participated (women: n = 11 (91.7%) and men: n = 1 (8.3%), mean age = 31.25 years, D.E. = 5.78). The Corah Dental Anxiety Scale was applied, the patient’s mood was assessed with a Likert scale before and after receiving the dental treatment, and their blood pressure was recorded for each of the three stages of treatment. A therapy dog accompanied the participants during the dental procedure. The main results indicated that a decrease in discomfort was perceived during the intervention, and there was also an improvement in the patient’s evaluation of the experience. The results are based on the decrease in patients’ blood pressure when taken in the middle of the dental treatment.
Revisiting Oral Fluoroquinolone and Multivalent Cation Drug-Drug Interactions: Are They Still Relevant?
Authors: Pitman Stuart K. , Hoang Uyen T. P. , Wi Caren H. , Alsheikh Mona , Hiner Dakota A. , Percival Kelly M.
Published: July 2019

Fluoroquinolones are a widely-prescribed, broad-spectrum class of antibiotics with several oral formulations notable for their high bioavailability. For certain infections, fluoroquinolones are the first line or only treatment choice. When administered orally, fluoroquinolones require proper administration to ensure adequate systemic absorption and, thereby, protect patients from treatment failure. Oral drug preparations that contain multivalent cations are well known to chelate with fluoroquinolones in the gastrointestinal tract; co-administration may lead to clinically significant decreases in oral fluoroquinolone bioavailability and an overall increase in fluoroquinolone-resistant bacteria. Based on a search and evaluation of the literature, this focused review describes oral fluoroquinolone-multivalent cation drug-drug interactions and their magnitude and offers several clinical management strategies for these potentially clinically significant interactions.
Protective Effects of Dendropanax morbifera against Cisplatin-Induced Nephrotoxicity without Altering Chemotherapeutic Efficacy
Authors: Kim Ji Su , Kim Kyeong Seok , Son Ji Yeon , Kim Hae Ri , Park Jae Hyeon , Lee Su Hyun , Lee Da Eun , Kim In Su , Lee Kwang Youl , Lee Byung Mu , Kwak Jong Hwan , Kim Hyung Sik
Published: July 2019

Use of the chemotherapeutic agent cisplatin (CDDP) in cancer patients is limited by the occurrence of acute kidney injury (AKI); however, no protective therapy is available. We aimed to investigate the renoprotective effects of Dendropanax morbifera water extract (DM) on CDDP-induced AKI. Male Sprague-Dawley rats (six animals/group) received: Vehicle (control); CDDP (6 mg/kg, intraperitoneally (i.p.); DM (25 mg/kg, oral); or DM + CDDP injection. CDDP treatment significantly increased blood urea nitrogen (BUN), serum creatinine (sCr), and pro-inflammatory cytokines (IL-6 and TNF-α), and severely damaged the kidney architecture. Urinary excretion of protein-based AKI biomarkers also increased in the CDDP-treated group. In contrast, DM ameliorated CDDP-induced AKI biomarkers. It markedly protected against CDDP-induced oxidative stress by increasing the activity of endogenous antioxidants and reducing the levels of pro-inflammatory cytokines (IL-6 and TNF-α). The protective effect of DM in the proximal tubules was evident upon histopathological examination. In a tumor xenograft model, administration of DM enhanced the chemotherapeutic activity of CDDP and exhibited renoprotective effects against CDDP-induced nephrotoxicity without altering chemotherapeutic efficacy. Our data demonstrate that DM may be an adjuvant therapy with CDDP in solid tumor patients to preserve renal function.
Do We Utilize Our Knowledge of the Skin Protective Effects of Carotenoids Enough?
Authors: Balić Anamaria , Mokos Mislav
Published: July 2019

Due to their potential health-promoting effects, carotenoids have drawn both scientific and public attention in recent years. The primary source of carotenoids in the human skin is diet, mainly fruits, vegetables, and marine product, but they may originate from supplementation and topical application, too. In the skin, they accumulate mostly in the epidermis and act as a protective barrier to various environmental influences. Namely, the skin is exposed to numerous environmental factors, including ultraviolet radiation (UVR), air pollution, and smoking, that cause oxidative stress within the skin with consequent premature (extrinsic) aging. UVR, as the most prominent environmental factor, may cause additional detrimental skin effects, such as sunburn, DNA damage, and skin cancer. Therefore, photoprotection is the first line intervention in the prevention of premature aging and skin cancer. Numerous studies have demonstrated that carotenoids, particularly β-carotene, lycopene, lutein, and astaxanthin, have photoprotective effects, not only through direct light-absorbing properties, but also through their antioxidant effects (scavenging reactive oxygen species), as well as by regulation of UV light-induced gene expression, modulation of stress-dependent signaling, and/or suppression of cellular and tissue responses like inflammation. Interventional studies in humans with carotenoid-rich diet have shown its photoprotective effects on the skin (mostly by decreasing the sensitivity to UVR-induced erythema) and its beneficial effects in prevention and improvement of skin aging (improved skin elasticity and hydration, skin texture, wrinkles, and age spots). Furthermore, carotenoids may be helpful in the prevention and treatment of some photodermatoses, including erythropoietic protoporphyria (EPP), porphyria cutanea tarda (PCT) and polymorphous light eruption (PMLE). Although UVR is recognized as the main etiopathogenetic factor in the development of non-melanoma skin cancer (NMSC) and melanoma, and the photoprotective effects of carotenoids are certain, available studies still could not undoubtedly confirm the protective role of carotenoids in skin photocarcinogenesis.
Implementation of an Attribute-Based Encryption Scheme Based on SM9
Authors: Shi Yang , Ma Zhiyuan , Qin Rufu , Wang Xiaoping , Wei Wujing , Fan Hongfei
Published: July 2019

In recent years, attribute-based encryption (ABE) has been widely applied in mobile computing, cloud computing, and the Internet of things, for supporting flexible and fine-grained access control of sensitive data. In this paper, we present a novel attribute-based encryption scheme that is based on bilinear pairing over Barreto and Naehrig curves (BN-curves). The identity-based encryption scheme SM9, which is a Chinese commercial cryptographic standard and a forthcoming part of ISO/IEC11770-3, has been used as the fundamental building block, and thus we first introduce SM9 and present our SM9 implementation in details. Subsequently, we propose the design and implementation of the ABE scheme. Moreover, we also develop a hybrid ABE for achieving lower ciphertext expansion rate when the size of access structure or plaintext is large. The performance and energy consumption of the implementation of the proposed ABE and its hybrid version are evaluated with a workstation, a PC, a smart phone, and an embedded device. The experimental results indicated that our schemes work well on various computing platforms. Moreover, the proposed schemes and their implementations would benefit developers in building applications that fulfill the regulatory compliance with the Chinese commercial cryptographic standard since there is no existing ABE scheme compatible with any Chinese cryptographic standard.
A Time Integration Method Based on Galerkin Weak Form for Nonlinear Structural Dynamics
Authors: Xing Qinyan , Yang Qinghao , Wang Weixuan
Published: July 2019

This paper presents a step-by-step time integration method for transient solutions of nonlinear structural dynamic problems. Taking the second-order nonlinear dynamic equations as the model problem, this self-starting one-step algorithm is constructed using the Galerkin finite element method (FEM) and Newton–Raphson iteration, in which it is recommended to adopt time elements of degree m = 1,2,3. Based on the mathematical and numerical analysis, it is found that the method can gain a convergence order of 2m for both displacement and velocity results when an ordinary Gauss integral is implemented. Meanwhile, with reduced Gauss integration, the method achieves unconditional stability. Furthermore, a feasible integration scheme with controllable numerical damping has been established by modifying the test function and introducing a special integral rule. Representative numerical examples show that the proposed method performs well in stability with controllable numerical dissipation, and its computational efficiency is superior as well.
Adsorption of Nitrate by a Novel Polyacrylic Anion Exchange Resin from Water with Dissolved Organic Matters: Batch and Column Study
Authors: Sun Yue , Zheng Weisheng , Ding Xinchun , Singh Rajendra Prasad
Published: July 2019

A novel anion exchange resin AEE-3 was synthesized by N-alkylation of a weakly basic polyacrylic anion exchanger D311 with 1-bromopropane to effectively remove nitrate (NO3−-N) from aqueous solution. The related finding revealed that its adsorption isotherm obeyed the Langmuir model well, and the second-order model was more validated for the NO3−-N adsorption kinetics study. Compared to commercially-available polystyrene-based nitrate specialty resin Purolite A 520E (A520E), AEE-3 resin has a higher adsorbed amount and better regeneration performance toward NO3−-N in the existence of dissolved organic matter (DOM) using static and dynamic methods. Notably, a real secondary treated wastewater (STWW) obtained from a local municipal wastewater treatment plant was also assessed for NO3−-N removal in fixed-bed columns. Observations from this study indicated that AEE-3 could effectively remove NO3−-N from contaminated surface water.
Friction Coefficient Compensation Control in Synchronizer Synchronization Process for Transmission
Authors: Yan Hao , Xu Zhaoping , Yuan Juntang , Liu Meiyan , Ge Wenqing
Published: July 2019

In the synchronization process of a synchronizer, the friction coefficient of the friction cone is changed because of friction heat. In this paper, the influence of a changing friction coefficient on shift quality was analyzed. The quantitative relationship between friction coefficient and its influencing factors was studied through a synchronizer synchronization process test bench. Based on the quantitative analysis and an optimal shift force control method, a compensation control strategy for friction coefficient was established. Moreover, the effectiveness of the compensation control was verified through simulation and experiment. The results showed that the friction coefficient was maintained near the expected value of 0.08 after the compensation control, the shifting speed difference the synchronous time was shortened by nearly 0.12 s, and the sliding friction was reduced by 4.64 J under the experimental conditions. The analysis and compensation of the friction coefficient provide a theoretical reference for improving shift quality.
Beige Fat, Adaptive Thermogenesis, and Its Regulation by Exercise and Thyroid Hormone
Authors: Phillips Kevin J.
Published: July 2019

While it is now understood that the proper expansion of adipose tissue is critically important for metabolic homeostasis, it is also appreciated that adipose tissues perform far more functions than simply maintaining energy balance. Adipose tissue performs endocrine functions, secreting hormones or adipokines that affect the regulation of extra-adipose tissues, and, under certain conditions, can also be major contributors to energy expenditure and the systemic metabolic rate via the activation of thermogenesis. Adipose thermogenesis takes place in brown and beige adipocytes. While brown adipocytes have been relatively well studied, the study of beige adipocytes has only recently become an area of considerable exploration. Numerous suggestions have been made that beige adipocytes can elicit beneficial metabolic effects on body weight, insulin sensitivity, and lipid levels. However, the potential impact of beige adipocyte thermogenesis on systemic metabolism is not yet clear and an understanding of beige adipocyte development and regulation is also limited. This review will highlight our current understanding of beige adipocytes and select factors that have been reported to elicit the development and activation of thermogenesis in beige cells, with a focus on factors that may represent a link between exercise and ‘beiging’, as well as the role that thyroid hormone signaling plays in beige adipocyte regulation.
Changes in Metabolisms of Antioxidant and Cell Wall in Three Pummelo Cultivars during Postharvest Storage
Authors: Liu Juan , Liang Lei , Jiang Yueming , Chen Junjia
Published: July 2019

The juice sacs of pummelo fruit is susceptible to softening during storage at 25 °C, which causes quality deterioration and flavor loss during postharvest pummelo storage. This study investigated the changes in metabolisms of antioxidant and cell wall in juice sacs of three pummelo cultivars—Hongroumiyou (HR), Bairoumiyou (BR) and Huangroumiyou (HuR)—during postharvest storage. The results revealed that, with the extension of storage, the juice sacs of three pummelo cultivars exhibited a decrease in total antioxidant capacity (TAC), DPPH and ABTS radical scavenging activity; a decline in total phenols (TP) content and an increase firstly then a decrease in total ascorbic acid (TAA) content; and a decrease in lipoxygenase (LOX) activity and a rise initially, but a decline in activities of ascorbate peroxidase (APX) and glutathione peroxidase (GPX). Additionally, increased water-soluble pectin (WSP), but declined propectin, ionic-soluble pectin (ISP) and chelator-soluble pectin (CSP); as well as an increase from 0 d to 60 d then followed by a decline in activities of pectinesterase (PE), polygalacturonase (PG) and pectate lyase (PL) were observed. These results suggested that the metabolisms of antioxidant and cell wall could result in softening and senescence of pummelo fruit.
Genome-Wide Association Study of Metabolic Syndrome Reveals Primary Genetic Variants at CETP Locus in Indians
Authors: Prasad Gauri , Bandesh Khushdeep , Giri Anil , Kauser Yasmeen , Chanda Prakriti , Parekatt Vaisak ,   INDICO, Mathur Sandeep , Madhu Sri , Venkatesh Pradeep , Bhansali Anil , Marwaha Raman , Basu Analabha , Tandon Nikhil , Bharadwaj Dwaipayan
Published: July 2019

Indians, a rapidly growing population, constitute vast genetic heterogeneity to that of Western population; however they have become a sedentary population in past decades due to rapid urbanization ensuing in the amplified prevalence of metabolic syndrome (MetS). We performed a genome-wide association study (GWAS) of MetS in 10,093 Indian individuals (6617 MetS and 3476 controls) of Indo-European origin, that belong to our previous biorepository of The Indian Diabetes Consortium (INDICO). The study was conducted in two stages—discovery phase (N = 2158) and replication phase (N = 7935). We discovered two variants within/near the CETP gene—rs1800775 and rs3816117—associated with MetS at genome-wide significance level during replication phase in Indians. Additional CETP loci rs7205804, rs1532624, rs3764261, rs247617, and rs173539 also cropped up as modest signals in Indians. Haplotype association analysis revealed GCCCAGC as the strongest haplotype within the CETP locus constituting all seven CETP signals. In combined analysis, we perceived a novel and functionally relevant sub-GWAS significant locus—rs16890462 in the vicinity of SFRP1 gene. Overlaying gene regulatory data from ENCODE database revealed that single nucleotide polymorphism (SNP) rs16890462 resides in repressive chromatin in human subcutaneous adipose tissue as characterized by the enrichment of H3K27me3 and CTCF marks (repressive gene marks) and diminished H3K36me3 marks (activation gene marks). The variant displayed active DNA methylation marks in adipose tissue, suggesting its likely regulatory activity. Further, the variant also disrupts a potential binding site of a key transcription factor, NRF2, which is known for involvement in obesity and metabolic syndrome.
The Presence of Polysaccharides, Glycerol, and Polyethyleneimine in Hydrogel Enhances the Performance of the Glucose Biosensor
Authors: Fois Marco , Arrigo Paola , Bacciu Andrea , Monti Patrizia , Marceddu Salvatore , Rocchitta Gaia , Serra Pier Andrea
Published: July 2019

The use of amperometric biosensors has attracted particular attention in recent years, both from researchers and from companies, as they have proven to be low-cost, reliable, and very sensitive devices, with a wide range of uses in different matrices. The continuous development of amperometric biosensors, since their use involves an enzyme, is specifically aimed at keeping and increasing the catalytic properties of the loaded protein, so as to be able to use the same device over time. The present study aimed to investigate the impact of glycerol and polysaccharides, in the presence of polycationic substances to constitute a hydrogel, in enhancing the enzymatic and analytic performance of a glucose biosensor. Initially, it was possible to verify how the deposition of the starch-based hydrogel, in addition to allowing the electropolymerization of the poly(p-phenylenediamine) polymer and the maintenance of its ability to shield the ascorbic acid, did not substantially limit the permeability towards hydrogen peroxide. Moreover, different biosensor designs, loading a mixture containing all the components (alone or in combination) and the enzyme, were tested in order to evaluate the changes of the apparent enzyme kinetic parameters, such as VMAX and KM, and analytical response in terms of Linear Region Slope, highlighting how the presence of all components (starch, glycerol, and polyethyleneimine) were able to substantially enhance the performance of the biosensors. The surface analysis of the biosensors was performed by scanning electron microscope (SEM). More, it was shown that the same performances were kept unchanged for seven days, proving the suitability of this biosensor design for short- and mid-term use.