bluuebunny/crossref_metadata_2025 huggingface dataset:
PEPTIDES: A NEW THERAPEUTIC APPROACH
Authors: Preet Payal
Published: March 2018

Peptide therapeutics have played a notable role in medical practice since the advent of insulin therapy in the 1920s. Over 60 peptide drugs are approved in the United States and other major markets, and peptides continue to enter clinical development at a steady pace. Peptide drug discovery has diversified beyond its traditional focus on endogenous human peptides to include a broader range of structures identified from other natural sources or through medicinal chemistry efforts. Peptides are recognized for being highly selective and efficacious and, at the same time, relatively safe and well tolerated. Consequently, there is an increased interest in peptides in pharmaceutical research and development (R and D), and approximately 140 peptide therapeutics are currently being evaluated in clinical trials. Given that the low-hanging fruits in the form of obvious peptide targets have already been picked, it has now become necessary to explore new routes beyond traditional peptide design. Examples of such approaches are multifunctional and cell-penetrating peptides, as well as peptide drug conjugates. In regards to patient compliance for drug delivery, oral drug delivery is generally the preferred route of administration. However, parental injection of peptide drugs has always been the primary method of peptide drug administration. Nevertheless, oral delivery of peptide drug presents a significant challenge due to the enzymatic degradation by enzymes in the GI tract and the poor penetration of the peptides across gastro-intestinal epithelium membranes, particularly for adults. Therefore, a novel peptide drug analogue or pro-drug that both protect peptide drugs from degradation by the enzymes in the GI tract that also improves its penetration across the intestinal epithelium membrane would greatly advance the development of peptide drugs as effective candidates for the treatment of various diseases.
PHYTOCHEMICAL SCREENING, QUANTITATIVE ANALYSIS OF PRIMARY AND SECONDARY METABOLITES OF ACACIA ARABICA BARK
Authors: Deshmukh Mahendra A. , Theng Madhuri A.
Published: March 2018

The study includes phytochemical screening and quantification of primary and secondary metabolites like chlorophyll, carbohydrates, protein, lipids, phenol, tannin and flavonoids from Acacia arabica bark. For these purpose aqueous extract of bark was prepared by “Soxhlet extraction method”. The result of these study suggests that the Acacia arabica bark in which presence of primary and secondary metabolites.
SPECTROSCOPIC STUDIES ON POUZOLZIA WIGHTII BENN
Authors: M. Syed Ali Fathima , M Johnson
Published: March 2018

Objective: The present study was aimed to reveal the spectroscopic profile (UV-Vis and FT-IR) of Pouzolzia wightii Benn. Methods: To detect the UV-Vis spectroscopic profile of P. wightii crude extracts were examined under UV-Vis Shimadzu spectrophotometer with the wavelength ranged from 100 to 1100 nm. About 1 mg of different extracts of petroleum ether, chloroform, ethyl acetate and acetone, ethanolic extracts of P. wightii were separately made into thin discs with 10-100 mg of potassium bromide using a mould and pressed under anhydrous conditions. The pellets were measured in an automatic recording FT-IR Spectrophotometer (Shimadzu 8400S) in the range of 400 to 4000 cm-1Results: In UV-Vis analysis, P. wightii petroleum ether extracts showed more number of peaks in roots (15) than other studied parts. Chloroform and ethyl acetate extracts of P. wightii leaves observed 9 peaks and acetone extracts of P. wightii stem showed 10 peaks. Medicinal property of plant extracts are confirmed by the presence of secondary metabolites. FT-IR analysis of ethyl acetate extracts of P. wightii leaves, stem and root observed the highest number of (16, 12 and 16) functional compounds.Conclusion: These UV-Vis and FT-IR spectroscopic results may be used as a pharmacognostic marker in the pharmaceutical industries and can be used as a chemometric tool to distinguish the studied P. wightii leaves, stem and root. The present study used to find out the bioactive compounds which may be subjected to subsequent target isolation. Further research will be needed for the structural characterization of the isolated compound by the use of different analytical methods such as NMR and mass spectrophotometer.
NERIUM OLEANDER: IT’S APPLICATION IN BASIC AND APPLIED SCIENCE: A REVIEW
Authors: Farooqui Saabiya , Tyagi Tulika
Published: March 2018

Nerium oleander is an important medicinal plant in Indian folk medicine. It is a potentially lethal plant in many cases and poisoning is reported in tropical and subtropical parts of the world as well as a number of suicidal cases are also prevalent in South Asian countries, especially in India and Sri Lanka. All parts of the plant are toxic and contain a variety of cardiac glycosides which includes neriin, oleandrin, cardenolides, gentiobiosyl and odoroside. This plant species also produce secondary metabolites such as alkaloids, flavonoids and steroids which have pharmacological applications. The important pharmacological activities are antibacterial, anthelmintic, anti-inflammatory, hepatoprotective, immunopotential, anti-pyretic, antioxidant, antifungal, anticancer and anti-HIV activity. This review describes the evidence-based information regarding pharmacological activity as well as phytochemicals of this plant.
ANTI-OXIDATIVE, ANTI-INFLAMMATORY AND ANTI-ATHEROSCLEROTIC EFFECT OF TAURINE ON HYPERCHOLESTEROLEMIA INDUCED ATHEROSCLEROTIC RATS
Authors: Sharma Harsha , Joshi Ankita , Lad Harsha , Bhatnagar Deepak
Published: March 2018

Objective: The present study evaluates the antioxidant, anti-inflammatory and anti-atherosclerotic potency of taurine (2-amino ethane sulfonic acid) when administered orally to hypercholesterolemia induced atherosclerotic rats.Methods: The experimental atherosclerosis was induced by feeding rats with an atherogenic diet comprising of the normal rat chow supplemented with 4 % cholesterol, 1 % cholic acid and 0.5 % thiouracil (CCT diet) for 20 d. Treatment with atorvastatin (10 mg/kg body weight) and taurine (2 % in drinking water) was given to atherosclerotic rats to study antioxidant enzymes (superoxide dismutase, catalase, glutathione-S-transferase), lipid peroxidation in liver, glutathione reductase and protein carbonyl content, extent of DNA damage using the alkaline comet assay, assaying pro-inflammatory cytokines and quantifying atherosclerotic lesions.Results: Oral supplementation of 2 % taurine to hypercholesterolemic rats modulated antioxidant status and significantly reduced malondialdehyde (MDA) content (P<0.05). The extent of DNA damage was also significantly reduced as observed by a reduction in the comet tail index (P<0.05). Taurine exhibited anti-inflammatory activity by significantly inhibiting TNF-α (tumor necrosis factor) and IL-1α (inter leukine) and also inhibited atherosclerotic lesions by clearing lipid deposits on the intimal surface of the rat aorta.Conclusion: Oral administration of taurine to rats showed antioxidant and anti-inflammatory activity by modulating oxidants in favor of reducing oxidative stress and also showed anti-atherosclerotic activity in hypercholesterolemia-induced atherosclerosis.
Oil’s Rural Reach: Social Licence in Saskatchewan’s Oil-Producing Communities
Authors: Eaton Emily Marie , Enoch Simon
Published: March 2018

Background This article investigates the unusually robust social licence that the oil industry enjoys in Saskatchewan, where rural oil-producing communities exhibit what Thomson and Boutilier characterize as “psychological identification” with industry.

Analysis The authors explore what this psychological identification looks like on the ground by examining the corporate social responsibility practices of the oil industry. They probe the beliefs and perceptions of variously positioned individuals living in oil-producing communities through 25 interviews.

Conclusion and implications The research findings point to the need to understand social licence as much more than only the practice of garnering consent for local operations. Rather, the intense identification with industry in the communities studied clearly favoured the reproduction of industry discourses for understanding a wide array of energy issues.
In the Corporate Interest: Fossil Fuel Industry Input into Alberta and British Columbia’s Climate Leadership Plans
Authors: Blue Gwendolyn , Rajewicz Lise , Daub Shannon , Yunker Zoë
Published: March 2018

Background This article examines the narrative strategies used by fossil fuel industries in responding to and shaping Alberta and BC’s climate leadership plans.

Analysis This article makes inferences about fossil fuel industry influence by examining submissions of industry players to both regions’ public consultation processes.

Conclusions and implications Key themes include: a need to take a leadership stance, a balance between environmental protection and economic growth, an appeal to protect industry competitiveness, and an emphasis on demand-side policies. These themes align with a policy discourse of weak ecological modernization and are central to advisory panel recommendations and subsequent subnational climate policies that facilitate market expansion and increased oil and gas production at a time when strong greenhouse gas (GHG) mitigation efforts are urgently required.
Energy’s Citizens: The Making of a Canadian Petro-Public
Authors: Wood Tim
Published: March 2018

Background  Canada’s fossil fuel industry has recently put citizen outreach at the centre of its political strategy. This is manifest in a public outreach campaign known as Canada’s Energy Citizens (CEC), undertaken by the Canadian Association of Petroleum Producers (CAPP).Analysis  This article uses interviews with CEC organizers and members to demonstrate how participation subsidies are used to enlist members. While much scholarly literature assumes corporate grassroots campaigns will hide the use of professional public relations labour and industry ties, findings show instead that CEC foreground its members’ professional backgrounds and connections to the oil sector.  Conclusions and implications  Transparency does ideological work in the campaign, framing pro-oil advocacy as a licit social aim, and public relations labour as a normative model of citizen political participation.Contexte  L’industrie des combustibles fossiles au Canada a récemment centré sa stratégie politique sur la sensibilisation des citoyens. Par exemple, l’Association canadienne des producteurs pétroliers (ACPP) a mené une campagne de sensibilisation publique du nom de « Canada’s Energy Citizens » (CEC).Analyse  Cet article a recours à des entrevues avec des organisateurs et membres de CEC afin de démontrer dans quelle mesure cette campagne de sensibilisation utilise des subventions de participation afin de recruter ses membres. Plusieurs recherches savantes font la supposition que les campagnes locales menées par les entreprises ont tendance à cacher leurs liens avec l’industrie et leur recours aux services de relations publiques, mais les données de cette étude démontrent que CEC, au contraire, affiche les liens professionnels de ses membres au secteur pétrolier.Conclusions et implications  Cette transparence sert la campagne d’un point de vue idéologique, présentant l’appui à l’industrie pétrolière comme un objectif social légitime, et les relations publiques comme moyen d’encourager l’engagement politique des citoyens.
Framing the Pipeline Problem: Civic Claimsmakers and Social Media
Authors: Bakardjieva Maria , Felt Mylynn , Teruelle Rhon
Published: March 2018

Background  This article responds to the need for additional research into the role that social media play in the debate on energy transition in Canada.Analysis  Based on a qualitative case study of the most recent protests against the Kinder Morgan pipeline project, this article raises questions concerning the strengths and weaknesses of the contemporary communication opportunity structure for “claimsmaking” (as Joel Best defines it in Social Problems) and achieving public resonance by the civic grassroots in Canada.Conclusions and implications  This article investigates the ways in which social media have become a site for framing collective action by pipeline opponents. It documents how citizens and civic organizations combine online and offline tools and tactics to take part in the shaping of public understanding of pipeline projects in Canada and in the influencing of energy policy and decision-making.Contexte  Cet article répond au besoin de recherches additionnelles sur le rôle joué par les médias sociaux dans le débat sur la transition énergétique au Canada.Analyse  Cet article se base sur une étude de cas qualitative sur les manifestations les plus récentes contre le projet de pipeline Kinder Morgan afin de relever les forces et faiblesses de la structure d’opportunités communicationnelles contemporaines pour la formulation de demandes (telle que définie par Joel Best dans Social Problems) et la conscientisation du public par les mouvements populaires au Canada.Conclusions et implications  Cet article explore les manières dont les médias sociaux sont devenus un site important pour déterminer l’action collective que les opposants aux pipelines peuvent mener. Il documente comment les citoyens et les organismes civiques combinent des outils et tactiques en ligne et hors ligne afin d’influencer la perception publique à l’égard de projets de pipeline au Canada ainsi que les politiques et la prise de décisions sur l’énergie en général.This article responds to the need for additional research into the role that social media play in the debate on energy transition in Canada. Based on a qualitative case study of the most recent protests against the Kinder Morgan pipeline project, we raise questions concerning the strengths and weaknesses of the contemporary communication opportunity structure forclaimsmaking and achieving public resonance by the civic grassroots in Canada. We investigate the ways in which social media have become a site for framing collective action by pipeline opponents. We document how citizens and civic organizations combine online and offline tools and tactics to take part in the shaping of public understanding of pipeline projects in Canada and to influence energy policy and decision-making.
From Public Relations to Mob Rule: Media Framing of Social Licence in Canada
Authors: Gunster Shane , Neubauer Bob
Published: March 2018

Background  Social licence refers to the idea that corporations and governments require broad public support for resource development projects from affected communities, citizens, and stakeholders. Talk of social licence has become pervasive in media discussions of resource development in Canada and especially prominent in debates around oil pipelines. Analysis  This article explores changing Canadian newspaper coverage of social licence over the past two decades. It identifies and analyzes the formation of four distinct “logics” of social licence: corporate, regulatory, oppositional, and conservative attack.Conclusions and implications  This analysis provides a more robust framework for understanding how different groups have advanced competing visions of social licence within the public sphere, while illuminating the active role that news media have played in shaping the definition of social licence to fit their own editorial cultures.Contexte  « Permis social » se rapporte à l’idée que les sociétés commerciales et les gouvernements requièrent, pour le développement des ressources, l’appui des communautés, citoyens et parties prenantes concernés. Cette idée de permis social apparaît souvent dans les discours médiatiques sur le développement énergétique au Canada, surtout par rapport aux oléoducs.Analyse   Cet article explore les changements dans la manière dont les journaux canadiens ont traité du permis social au cours des deux dernières décennies. Par rapport à ce concept, il identifie et analyse la formation de quatre « logiques » différentes : corporative, règlementaire, oppositionnelle et conservatrice attaquante.Conclusion et implications  Cette analyse fournit un cadre plus robuste pour comprendre comment divers groupes ont mis l’accent dans la sphère publique sur des interprétations divergentes du permis social. D’autre part, elle élucide le rôle actif joué par les médias d’information dans la définition, selon leurs orientations éditoriales, de ce qu’est le permis social.
Tender puentes, entretejer esfuerzos y saberes para el logro de la movilidad profesional y estudiantil en la Universidad Estatal a Distancia de Costa Rica
Authors: Rivera-Turcios Grethel , Ovares-Garmendia Ingrid
Published: March 2018

La internacionalización y la movilidad académica y estudiantil representan la estrategia que la Universidad Estatal a Distancia (UNED) ha implementado para expandir las fronteras pedagógicas entre instituciones de educación superior a nivel mundial. El apoyo del Acuerdo para el Mejoramiento Institucional (AMI) y el Plan de Mejoramiento Institucional ha potenciado la participación de académicos y estudiantes en actividades académicas. En el caso específico de este documento se refiere a la experiencia llevada a cabo por la Cátedra de Educación Preescolar y la Universidad Pedagógica Nacional de Bogotá, Colombia, la cual, según se relata, resultó exitosa.
Application of ecodrainage system in reducing the potential for flooding in the District of Sampang
Authors: Andikha Fauzan , Yuniarto Adhi
Published: March 2018

Kamoning River watershed is one of the watersheds in Sampang. Sampang City experienced flooding almost every year caused by the overflow of the River Kamoning. One of the causes of flooding in that city is the high rainfall and a lack of rainwater catchment areas in the upper and middle Kamoning River watershed. To overcome these problems, it is necessary to use a system of flood discharge reduction eco drainage in the upstream and in the middle of Kamoning River watershed. This study used two scenarios of eco-drainage system: first is to change the land use in combination with the creation of retention ponds, the second scenario is to change the land use in combination with the creation of infiltration wells. From the analysis of large unknown, designed-flood discharge of 50 year-return period of Kamoning River basin is 289.361 m3/ sec. By using the first scenario, the designed-flood discharge can be reduced by 199.59 m3/s or 31.02%, while large designed-flood discharge can be reduced by 205.20 m3/s or 29.08% using second scenario. Efforts to reduce the discharge flood in Sampang can be effectively conducted by using the scenario 1.
Study of urban drainage system based on spatial structure plan
Authors: Irawan Rahmat , Pandebesie Ellina S. , Purwanti Ipung Fitri
Published: March 2018

The whole planning of urban infrastructure development should refer to the Detailed Spatial Planning that has been developed by the Regional Government. One of them is the drainage system planning which also needs to pay attention to the land use change plan. This change would cause an increase of run-off coefficient as a result of the increasing number of structure-covered land. Based on the land use planning of Spatial Structure Planning 2034, there was an increase in land cover with a total area of 75 hectares. Therefore, it is necessary to evaluate the urban drainage system in order to avoid problems in the future. Flood discharge was calculated using the rational formula applying run-off coefficient according to spatial structure plan. The analysis of the existing drainage system was carried out to find out whether it is still capable of accommodating the discharge according to Spatial Structure Planning 2034. Based on the drainage channel capacity analysis, 30 existing channels have to be repaired. They must be adjusted by widening the channel and increase the number of channels by 3191.36 m. Another effort to reduce the flood is by making 179 absorption wells in residential areas.
The strategy of domestic wastewater management in Kenjeran Surabaya
Authors: Wicaksono Daniel , Slamet Agus
Published: March 2018

Kenjeran is one of the districts in Surabaya with high-risk sanitation based on EHRA Surabaya 2012. Kenjeran has 4 (four) sub-districts that consists of Bulak Banteng, Tanah Kali Kedinding, Sidotopo Wetan, and Tambak Wedi. Bulak Banteng, Tanah Kali Kedinding, and Tambak Wedi have been identified as the areas in which open defecation still happened. The research is descriptive study by using field survey, interview, and comparison of existing condition with standards and regulations. The technical aspect study is conducted by analyzing the needs of wastewater infrastructure facilities based on the volume of domestic wastewater. 80 (eighty) Communal Sewage Treatment Plant (STP) were designed to solve domestic wastewater handling in 4 (four) sub-districts. Each of 80 (eighty) STP was designed to cover 75 â€“ 100 households. The domestic wastewater treatment used Anaerobic Baffled Reactor Technology. An example of STP design was conducted in Dukuh Bulak Banteng with the coverage of 100 households.
A high efficiency non-inverting multi device buck-boost DC-DC converter with reduced ripple current and wide bandwidth for fuel cell low voltage applications
Authors: Venkatesh Naik , Samuel Paulson
Published: March 2018

The voltage produced by the fuel cell (FC) device is unregulated and varies from 0.4 V to 0.8 V on full load to no-load respectively. When these devices are used in low voltage applications and output voltage lies between higher and lower values of input voltage range, it is required to connect a DCDC buck-boost converter to get a fixed output voltage. In this paper, a new noninverting multi device buck boost converter (MDBBC) is proposed, in which the multi device buck and boost converters are connected in cascade and operate individually either in buck or boost operating modes. The paper also includes the steady state analysis of MDDBC based on the state space averaging technique. A prototype model of proposed converter compatible with FCS-1000 Horizon FC model with rating of 270 W, 36 V is designed and developed. The proposed converter is experimentally validated with the results obtained from the prototype model, and results show the superiority of the converter with higher efficiency and lesser ripple current observed under steady state operation of the converter.
Castration as a consequence of the strengthening of the dynastic principle
Authors: Krsmanovic Bojana
Published: March 2018

The paper discusses examples of corporal mutilation that accompanied
intra-dynastic conflicts or clashes with real or potential pretenders to the
imperial throne. Castration was a known but rarely applied measure in the
political conflicts of the 7th and 8th century. Hence the two consecutive
cases of castration of all sons of the deposed emperor Michael I Rhangabe
(813) and the assassinated emperor Leo V the Armenian (820) deviated from the
previous Byzantine practice. The paper establishes that in these cases the
choice of castration as the most effective means of ensuring the future
political disqualification of the princes and their families was a result of
the strengthening dynastic principle, which was particularly noticeable in
the cases of the descendents of Constantine V from his third marriage. It
also highlights that castration was never used on the deposed emperor
autokrator, but only on the bearers of imperial dignities (co-emperors) or
simply princes with no imperial title. In examples where castration was used
to ensure political disqualification, it was not a sanction for an individual
wrongdoing (in other words, castration was not a penalty prescribed for a
specific transgression); if these cases were a matter of punishment at all,
the penalty was meant to sanction the entire bloodline (?????) rather than
the (innocent) individual. Castration was a milder form of punishment
compared to other forms of physical mutilation (severing of the nose, tongue
or ears; blinding). Due to the ambivalent attitude of the Byzantine society
towards eunuchs, castration did not necessarily lead to social
marginalization. Hence, it was applied more frequently during the reign of
the Macedonian dynasty, but prominent castrates were incorporated into the
official hierarchy as members of an order of eunuchs (?????? ??~? ????????).
Bilingual neume collections of the late middle ages - a new view at the well-known music sources
Authors: Peno Vesna
Published: March 2018

The long-term process of the byzantinization of Serbian culture and art,
intensified in the framework of complex political relations at the beginning
of the 15th century, is testified, among others, by the preserved bilingual
Greek-Slavonic musical manuscripts. As the primary sources in the
reconstruction of the Serbian church chanting art in the late Middle Ages,
but also the Byzantine-Serbian musical connections, the neum manuscripts
unambiguously confirm the existence of the bilingual worship practice at the
time of Despotovina Serbia. The long-held views on the dated two neum
anthologies from the Great Lavra (E 108) and the National Library of Greece
(EVE 928), their scribes, composers and songs in this paper are critically
examined for the first time.
The Balanced Scorecard beyond Adoption
Authors: Gupta Gaurav , Salter Stephen B.
Published: March 2018

Utilizing the theoretical underpinnings of the actor-network theory (ANT) and neo-institutional theory, we develop and test a model of the relationship between organizational culture and the use of the balanced scorecard (BSC). The data are collected from 1,126 top management and other employees in 48 manufacturing companies in India. After primary data collection and using path analysis, we find that the usage of the BSC is dependent on organizational culture. Organizations that are future and performance oriented with a high level of power distance have higher levels of BSC usage. This usage is found to be lower in organizations that are collectivist and uncertainty avoidant.
Efecto de la crisis financiera mundial en la creación de valor económico de los bancos de la comunidad andina en el periodo 2007-2014
Authors: Jácome Ortega Xavier Omar , Jácome Ortega Mariella
Published: March 2018

Esta investigación tiene el objetivo de analizar el efecto de la crisis del sistema financiero mundial en la creación de valor económico de la banca de la Comunidad Andina durante el período 2007–2014, a partir del método del Valor Económico Agregado, y el análisis de las variables que caracterizan la generación de valor de los bancos según el referido modelo. Se definió un estudio no experimental, descriptivo, y de tendencia longitudinal. Se tomaron los datos proporcionados por fuentes oficiales de la banca en Bolivia, Colombia, Ecuador y Perú. Se calcularon los indicadores que inciden en la creación de valor económico de cada país, y, según el modelo de Valor Económico Agregado, la posición de cada sistema bancario que conforma la Región Andina. Posterior al año 2008, se evidenció una reducción en el Retorno sobre Patrimonio Inicial medido según el modelo, con una tendencia de menores rendimientos para los años del 2009 en adelante. Se encontró que la crisis impactó en el crecimiento de los activos, provocó una reducción en el rendimiento de los activos productivos y en el rendimiento de la cartera de crédito, constituyéndose estas variables en las más relevantes para el análisis del valor de los bancos de la región.
El nacionalismo musical en el Ecuador. Enfoque en el compositor ecuatoriano Gerardo Guevara
Authors: Viteri Villamar Claudio Aquiles
Published: March 2018

El presente artículo relaciona dos conceptos importantes: nacionalismo y música.  El nacionalismo surgió en países que estaban colonizados o gobernados por un país extranjero y deseaban la autonomía o independencia. Por su parte, el concepto de  música es entendido como el arte de interrelacionar los sonidos a través del ritmo, la melodía y la armonía. La música es un medio a través del cual es posible  expresar el nacionalismo de un país. Diferentes recursos pueden ser la pintura, la escultura, la literatura, entre otros.  El concepto de nacionalismo no es nuevo, nace en Europa a partir del siglo XIX y más específicamente a partir de 1830 en que las artes fueron los principales medios para manifestar la identidad nacional. Coincidiendo este año además, con la independencia de la República del Ecuador, y su establecimiento como país libre e independiente.  Así como el nacionalismo tiene sus defensores, también tiene sus opositores, quienes manifiestan que dicho concepto impone criterios rígidos y no admite posturas intermedias. En este trabajo, se describe al Ecuador en dos momentos históricos: antes y después del descubrimiento de América por parte de los españoles. De igual forma, se describe y explica el concepto de nacionalismo musical en el Ecuador, con enfoque en el compositor ecuatoriano Gerardo Guevara y los géneros musicales por él utilizados en la mayoría de sus obras.
Cultura organizacional con relación a la interacción comunicativa en las web empresariales
Authors: Ulloa Ana Rosario
Published: March 2018

ResumenExisten diversos procesos de comunicación con el uso del internet, herramienta que permite establecer una comunicación en diversos entornos. Al considerar el entorno social, el internet permite establecer una comunicación mediática con diferentes personas con intereses afines. El objetivo de este artículo es analizar en esta misma línea de interés la comunicación en el entorno económico tomando en cuenta la interacción comunicativa que realizan las compañías con sus usuarios. Para abordar el tema se consideran cuatro ejes principales que nacen desde la cultura organizacional de comunicación de las empresas que tienen sitios web. Se inicia con el estudio de las definiciones, las estructuras y sus funciones, el  segundo eje abarca la gestión de comunicación empresarial, el tercero incluye la tecnología en la gestión de los procesos de comunicación y el cuarto analiza la interpretación del mensaje que es la base para potenciar la comunicación interactiva. En este estudio se utiliza una metodología de  análisis descriptivo aplicada al  problema observado. Se usa el  método cualitativo en el contexto macro social reflejado a través de los mensajes publicados en las web empresariales y el método cuantitativo en un nivel micro social con el análisis de los datos estadísticos presentados por Instituciones de Gobierno.
Percepciones de la protesta: una aproximación parcial a quienes no se movilizan
Authors: Urbina Cortés Gustavo Adolfo
Published: March 2018

En este avance de investigación se presenta la dimensión subjetiva de la acción colectiva entre individuos movilizados y los que no se involucran. Por la importancia de los espectadores como potencial “ejército de reserva” para engrosar la protesta, se decidió establecer una comparación exploratoria entre un grupo con antecedentes de movilización y otro sin involucramiento. El objetivo primordial consistía en extraer algunas hipótesis que ayudaran a problematizar en forma parcial el vínculo, poco estudiado en México, entre la percepción de la protesta social, su dimensionamiento moral y su importancia para convocar a la participación.
Igualdad de oportunidades: Un reto político en la teoría liberal
Authors: Postigo Asenjo Marta
Published: March 2018

RESUMENEs frecuente oír a políticos y a funcionarios hacer referencia a políticas de igualdad de oportunidades para hombres y mujeres, para inmigrantes o discapacitados. En las páginas que siguen, trataré de mostrar algunas de las características comunes del concepto de igualdad de oportunidades tal y como lo presentan algunos autores liberales. Abordaré cuestiones tales como el papel que juegan las responsabilidades individuales y las colectivas en nuestras elecciones y ambiciones, los valores del mérito y la importancia que tienen el influjo de las circunstancia en nuestras vidas, en nuestras oportunidades y proyectos.PALABRAS CLAVEIGUALDAD DE OPORTUNIDADES-LIBERTAD-LIBERALISMOABTRACTFrecuently we see how polititians and public servants make reference to equality of opportunity policies focuses on men and women, inmigrants or handicaped people. In the following pages I will try to show some of the common characteristics of the equality of opportunity concept as it is elaborated by some liberal authoirs. I will consider issues like the role of individual and collective responsibilities over our choices and ambitions, the value of merits, and the influence of circumstances on our lifes, chances and projects.KEYWORDSEQUALITY OF OPPORTUNITY-FREDDOM-LIBERALISM
Sobre el pensamiento político y social de Václav Havel. Subsidios bibliográficos
Authors: Navarro Martínez Felipe
Published: March 2018

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SIMULAÇÃO NA MOVIMENTAÇÃO DE FRUTAS - EXPORTAÇÃO NO TERMINAL DE CARGA AÉREA
Authors: Silva Aline Cauane Baptista , Silva Rafael Inácio , Maiellaro João Roberto
Published: March 2018

O objetivo do estudo é demonstrar a viabilidade da simulação para ilustrar uma proposta de melhoria, auxiliando as tomadas de decisão. Como ferramenta para simulação foi utilizado o software Arena versão acadêmica, onde alguns recursos são limitados. Nosso estudo engloba uma situação no processo de exportação de frutas em um terminal de carga aérea, que foi observada a partir de um cenário real, porém adaptado a um cenário fictício de tempo e variedade/quantidade de carga. Mesmo neste cenário, foi possível ilustrar e analisar com clareza os níveis de utilização dos recursos envolvidos, chegando à conclusão que é possível simular diversas situações e apresentar diferentes propostas. Sabendo que quanto mais próximo o modelo chegar da realidade, mais viáveis podem ser as melhorias propostas e mais confiáveis serão as tomadas de decisão baseadas em modelos simulados.
Left atrial volume index is critical for the diagnosis of heart failure with preserved ejection fraction
Authors: Almeida Pedro , Rodrigues João , Lourenço Patricia , Maciel Maria Julia , Bettencourt Paulo
Published: March 2018

Background

Heart failure with preserved ejection fraction (HFpEF) is now well recognized but the identification of patients with HFpEF can be challenging. We aimed to evaluate the performance of tissue Doppler imaging indexes and left atrial size in HFpEF diagnosis.

Methods and Results

We designed a case–control study in which cases are patients with acute heart failure and controls are age-matched and sex-matched patients with multiple cardiovascular risk factors admitted to hospital because of stroke. An echocardiogram was performed with tissue Doppler imaging evaluation. Receiver operating curves (ROC) were obtained to identify the best cut-off of BNP, global longitudinal strain (GLS), E/E′ and left atrial volume index (LAVI) for the identification of patients with HFpEF whenever compared with those without heart failure.

We analyze data from 195 age-matched and sex-matched patients: 65 patients with heart failure with reduced ejection fraction, 65 patients with HFpEF and 65 stroke patients. The best cut-offs for identification of HFpEF patients when compared with the nonheart failure control group of patients with stroke were 15 for GLS, 15 for E/E′ ratio and 34 ml/m2 for LAVI. The area under the curve (AUC) for GLS was 0.81 (CI 0.72–0.90); for the ratio E/E′, the AUC was 0.79 (CI 0.70–0.88) and for LAVI, it was 0.90 (CI 0.84–0.96).

Conclusion

We observed that ecochardiographic indices of diastolic and systolic function do identify patients with HFpEF. Our results point towards LAVI, E/E’ ratio and GLS as relevant indices to identify patients with HFpEF, especially LAVI.
CÔNG THỨC NÀO CHO BÀI PHÁT BIỂU THUYẾT PHỤC CỦA CỰU TỔNG THỐNG MỸ BARACK OBAMA TẠI HÀ NỘI?
Authors: Nga Nguyen Thi Hang
Published: March 2018

Chuyến thăm chính thức kéo dài ba ngày của tổng thống Mỹ tại Việt Nam cuối tháng 5 năm 2016 nhận được nhiều bàn luận của người dân cũng như của báo chí, đặc biệt là báo chí mạng. Nhiều bài viết về sự kiện này hoặc khen quá mức, hoặc phủ nhận những đóng góp của chuyến thăm quan trọng này. Chúng tôi đã tiến hành nghiên cứu trường hợp đối với bài diễn văn này, tiếp cận từ nhiều chiều kích bao gồm diễn thuyết, tâm lí học và quốc tế học để tìm ra công thức cho tính thuyết phục của bài diễn văn: người nói có quyền lực gì, người nói tác động tới cảm xúc người nghe như thế nào và người nói đưa ra lí lẽ ra sao. Kết quả nghiên cứu sẽ có có ý nghĩa không chỉ về nghệ thuật diễn thuyết đối với diễn giả mà còn về khả năng tiếp nhận thông tin của người nghe trong một thế giới thông tin đa chiều, không giới hạn như hiện nay. Sự ngưỡng mộ hay phê phán nên bớt cảm tính, trào lưu và tăng tính khách quan, khoa học.
VỊ TRÍ KHÔNG GIÁP BIỂN: THÁCH THỨC CHO PHÁT TRIỂN TRONG BỐI CẢNH TOÀN CẦU HÓA
Authors: Phuc Duong Truong , Chuyen Truong Thi Kim
Published: March 2018

Toàn cầu hóa chia sẻ cơ hội cho tất cả các quốc gia nhưng không phải quốc gia nào cũng có khả năng tiếp cận những cơ hội đó để vươn lên phát triển. Với vị trí địa lý thật đặc biệt, các quốc gia không giáp biển ở châu Á, châu Phi, và châu Mỹ Latin thật sự gặp khó khăn trong tiến trình hòa nhập vào xu thế phát triển chung của thế giới. Bài viết sử dụng phương pháp phân tích tổng hợp nguồn tài liệu thứ cấp phong phú từ các nghiên cứu của các học giả và các báo cáo chính thức của các tổ chức có liên quan. Kết quả nghiên cứu cho thấy, các quốc gia đang phát triển không giáp biển phải đối mặt với các thách thức như vận tải quá cảnh, chi phí vận chuyển và đầu tư nước ngoài. Từ đó, bài viết nhận diện một số vấn đề phát triển trong bối cảnh toàn cầu hóa và đề xuất một số hàm ý chính sách cho sự phát triển của những quốc gia này.
ĐƯỜNG HƯỚNG HÀNH ĐỘNG: MỘT ĐƯỜNG HƯỚNG LÝ THUYẾT MỚI HAY ĐƯỜNG HƯỚNG GIAO TIẾP PHÁT TRIỂN NÂNG CAO?
Authors: Thuan Nguyen Quang
Published: March 2018

Đường hướng hành động - một đường hướng giáo học pháp mới - ra đời thật sự là một đóng góp quan trọng vào dạy và học ngoại ngữ. Tuy nhiên, còn rất ít các công trình nghiên cứu làm rõ đóng góp to lớn này, đặc biệt là làm rõ sự khác nhau và giống nhau giữa đường hướng giao tiếp và đường hướng hànhđộng. Bài viết này phân tích những định hướng giáo học pháp mới của đường hướng hành động, một đường hướng giáo học pháp ngoại ngữ mới, cơ sở lý thuyết của Khung tham chiếu châu Âu. Đặc biệt, bài viết phân tích so sánh những điểm giống nhau và khác nhau giữa hai đường hướng giao tiếp và đường hướng hành động, và khả năng tích hợp của hai đường hướng này để có thể áp dụng hiệu quả đường hướng hành động nói chung và Khung tham chiếu châu Âu nói riêng vào dạy và học ngoại ngữ. Kết quả phân tích cho thấy đường hướng hành động có nhiều điểm khác với đường hướng giao tiếp, đặc biệt là đoạn tuyệt về mặt khoa học luận với đường hướng giao tiếp và là một đường hướng giáo học pháp mới chứ không phải là đường hướng giao tiếp phát triển ở mức độ cao hơn.
Desain Kapal Feeder Tol Laut Trayek T-5
Authors: Kurniawan Abdy , Pramita Dienda Rieski
Published: March 2018

Perbandingan PDB antara Kawasan Timur Indonesia dan Kawasan Barat Indonesia, yaitu 18,6% berbanding 81,4% menunjukkan pemerataan ekonomi yang masih timpang antara Kawasan Barat Indonesia (KBI) dan Kawasan Timur Indonesia (KTI) yang berdampak pada disparitas harga yang tinggi. Melalui program Tol Laut, pemerintah berupaya meningkatkan konektivitas antara KBI dan KTI sekaligus mengurangi disparitas harga melalui angkutan laut yang terjadwal dan bersubsidi. Trayek T-5 dengan Ternate sebagai salah satu pelabuhan singgahnya diharapkan menjadi sub-distributor lanjutan untuk daerah hinterlandnya yang berupa wilayah kepulauan yang ditunjang dengan kapal feeder. Kajian ini bertujuan untuk menghasilkan desain kapal feeder yang optimal sesuai dengan karakteristik beberapa pelabuhan singgah yang dilakukan dengan beberapa metode seperti analisa operasi dan pra rancangan menggunakan metode kapal pembanding. Hasil penelitian menunjukkan bahwa kapal feeder yang optimal memiliki payload 729 ton kecepatan dinas 8 knot dengan frekuensi pelayaran 32 voyage per tahun.
Perancangan Sistem Pengukuran Kinerja Otoritas Pelabuhan
Authors: Pana Otto Baka , Fahmi Idqan , Damar Ario
Published: March 2018

Otoritas Pelabuhan adalah lembaga pemerintah di pelabuhan sebagai otoritas yang melaksanakan fungsi pengaturan, pengendalian, dan pengawasan kegiatan kepelabuhanan yang diusahakan secara komersial. Oleh karena itu perlu sebuah metode pengukuran kinerja yang komprehensif yang menyeleraskan visi dan misi organiasasi ini dalam menjawab kebutuhan dunia kepelabuhanan yang sudah semakin berkembang dan kompleks. Balanced scorecard  menawarkan suatu peta jalan yang sistematis, obyektif, dan komprehensif untuk menerjemahkan pernyataan visi dan misi ke dalam sekumpulan ukuran kinerja yang saling berkaitan. Perancangan sistem pengukuran kinerja Otoritas Pelabuhan mengambil studi kasus pada Kantor Otoritas Pelabuhan Utama Tanjung Priok karena dianggap lebih kompleks dan mewakili Otoritas Pelabuhan yang ada di Indonesia. Perancangan pengukuran ini mengambil metode balanced scorecard yang dilakukan dengan melibatkan pihak manajemen Otoritas Pelabuhan Utama Tanjung Priok dangan beberapa ahli manajemen kepelabuhan. Metode analisis yang diterapkan untuk pengolahan data adalah AHP (analytical hierarchy process). Hasil AHP menunjukan urutan kepentingan tiap perspektif pada balanced scorecard pelabuhan. Hasil dari penyebaran kuesioner diperoleh nilai pembobotan dari keempat perspektif balanced scorecard, yaitu: responden memilih perspektif pelanggan sebagai perspektif yang paling penting yang ditandai dengan nilai tertinggi yaitu sebesar 37,5% terhadap visi Otoritas Pelabuhan, perspektif pembelajaran dan pertumbuhan sebesar 31,5%, kemudian diikuti oleh perspektif keuangan sebesar 17,6%, dan yang terakhir adalah perspektif proses bisnis internal 13,4%.
Faktor yang Mempengaruhi Pekerja Komuter di Jabodetabek Menggunakan Moda Transportasi Utama
Authors: Setyodhono Sapto
Published: March 2018

Permasalahan di kota besar dan megapolitan, seperti Jabodetabek antara lain masalah transportasi, terutama kemacetan yang dapat mengakibatkan tingkat produktivitas pekerja komuter rendah dan biaya ekonomi tinggi.Terjadinya kemacetan antara lain disebabkan oleh perilaku masyarakat dalam memilih mode transportasi. Penelitian ini bertujuan untuk mengetahui faktor-faktoryang mempengaruhi pekerja komuter di Jabodetabek menggunakan modatransportasi utama ke tempat kerjanya, dengan mengolah dan menganalisis row data Survei Komuter di Jabodetabek yang dilakukan oleh BPS pada tahun 2014 dan dilengkapi dengan data sekunder lainnya. Analisis data dilakukan dengan metoda tabel silang dan regresi logistik multinomial. Hasil penelitian menunjukan bahwa:umur, jenis kelamin, pendidikan, status pekerja, rata-rata penghasilan, jarak dan lama perjalanansertabiaya transpotasi berpengaruh terhadap pemilihan mode transportasi, kecuali bagipekerja komuter berstatus sebagai pekerjamandiri yang menggunakan moda transportasi APTB atau Transjakarta.
Perfil Psicológico de Prestação de Futebolistas Portugueses
Authors: Almeida Luís , Teixeira Carla M.
Published: March 2018

O objectivo do presente estudo foi comparar jogadores de futebol por nível competitivo, posição de jogo e experiência competitiva em autoconfiança, negatividade, atenção, imaginação, motivação, positivismo e atitude competitiva. A amostra foi composta por 424 jogadores de futebol com idades entre 18 e 36 anos. Os dados foram colectados por meio do questionário Perfil de Desempenho Psicológico. Os resultados sugeriram uma preparação psicológica não sistemática para a competição. Jogadores de alto nível mostraram melhores perfis psicológicos. Comparações por nível de competição mostraram melhores pontuações para competidores Regionais no nível de negatividade. Jogadores de nível nacional pontuaram mais alto na variável atenção / concentração. Comparações por posição mostraram que os guarda-redes apresentam níveis mais elevados de negatividade. Actuar em diferentes posições exige diferentes habilidades psicológicas. Comparações por idade e experiência competitiva mostram que quanto maior a experiência competitiva, melhor é o perfil psicológico. Influenciar o desenvolvimento de habilidades psicológicas. Também é possível inferir dos resultados que jogadores e dirigentes de equipes se beneficiariam muito com as habilidades psicológicas das intervenções de treinamento mental, promovendo o desenvolvimento de diferentes perfis psicológicos.
Confirmatory Factor Analysis of a Portuguese Version of the Pittsburgh Sleep Quality Index
Authors: Teixeira Carla M. , Caçador Andreia , Ferreira Tatiana M. , Vasconcelos-Raposo José
Published: March 2018

The purpose of the present study is to determine the reliability and factorial validity of a Portuguese version of the Pittsburgh Sleep Quality Index - PSQI (Buysse, Reynolds III, Monk, Berman, & Kupfer, 1989). Methods: A random sample of 252 children (113 girls; 139 boys) attending the secondary school, with an average age of 15.27 years (SD = 1.925) that completed the Portuguese PSQI (P-PSQI). The factor structure of the data was evaluated using confirmatory factor analysis. Results: Once the “use of sleep medication” component was removed from the model a good overall fit to the data was found (χ2/df = 1.194, GFI = .983, AGFI = .959, CFI = .980, RMSEA = .029 [.001- .076] AICsat = 42.0). These results confirm the theoretical strength of PSQI; however, we were unable to confirm the seven-factor structure proposed in the original version. Conclusions: The PSQI-P has good psychometric properties and is suitable for use in nomothetic research on sleep quality in Portuguese adolescents.
The 1st Annual McMaster Energy Week: Smart Energy City Competition
Authors: Joseph Damien , Chaudhari Hanu , Rogers Ryan
Published: March 2018

The following abstracts were selected as the top 3 finalists amongst the delegates chosen for the Smart Energy City Competition taking place during the 1st annual McMaster Energy Week. McMaster Energy Week is Canada's first student-led energy week that aims to take the complex and multi-faceted issue of climate change and present solutions towards building Canada's sustainable future. We are bringing together academia, industry, government, communities, and students to further the dialogue on Canadian environment and energy. For more information on this visit https://www.mcmasterenergyweek.com/ or email chair@mcmasterenergyweek.com.
PERFIL CLÍNICO-EPIDEMIOLÓGICO DE PACIENTES COM DOENÇA INFLAMATÓRIA INTESTINAL INTERNADOS NO HOSPITAL UNIVERSITÁRIO DA UNIVERSIDADE FEDERAL DO PIAUÍ.
Authors: Oliveira Tayná Cristinne Barros de , Lima Murilo Moura , Coelho Conceição de Maria De Sousa , Freitas Maria de Fátima De Alencar Bezerra , Silva Thaline Alves Elias da , Oliveira Jane Carneiro de , Borba Bárbara de Morais , Santos Priscila da Silveira , Parente José Miguel Luz
Published: March 2018

Doenças Inflamatórias Intestinais (DII) compreendem um grupo de enfermidades crônicas, das quais se sobressaem a Doença de Crohn (DC) e a Retocolite Ulcerativa (RCU). Estas doenças se caracterizam por períodos de recidiva e de remissão, por vezes necessitando de internações hospitalares. Determinar o perfil clínico-epidemiológico dos pacientes portadores de DII internados em hospital universitário de referência para DII, no Piauí, Brasil. Foram avaliadas 105 internações de 74 pacientes, no período de janeiro de 2015 a outubro de 2016. Foram analisadas variáveis demográficas, perfil clínico de acordo com a classificação de Montreal, tempo de internação hospitalar e ocorrência de cirurgia, infecção hospitalar e óbito. Foram incluídos 74 pacientes que foram submetidos a 105 internações hospitalares. Destas, 71 (67,6%) foram por DC e 34 (32,4%) por RCU. A média de idade foi de 36,5 anos para DC e 42,8 anos para RCU. Segundo a classificação de Montreal, as características clínicas mais comuns dos pacientes com DC foram a localização ileocolônica da doença (36,6%) e o comportamento não-estenosante e não penetrante (42,3%). A doença perianal ocorreu em 25,4% dos pacientes. O acometimento mais comum nos pacientes com RCU foi a retite (38,2%). O tempo médio de internação foi de 24,6 dias para DC e 17,9 dias para RCU. Intervenções cirúrgicas ocorreram em 39,4% das internações por DC e em 2,9% por RCU. Infecção hospitalar ocorreu em 14,1% das internações por DC e em 2,9% por RCU. Ocorreram 3 óbitos entre os pacientes com DC, sendo dois deles decorrentes de sepse. (Cont.)