bluuebunny/crossref_metadata_2025 huggingface dataset:
Source estimation for wavefield-reconstruction inversion
Authors: Fang Zhilong , Wang Rongrong , Herrmann Felix J.
Published: March 2018

Source estimation is essential for all wave-equation-based seismic inversions, including full-waveform inversion (FWI) and the recently proposed wavefield-reconstruction inversion (WRI). When the source estimation is inaccurate, errors will propagate into the predicted data and introduce additional data misfit. As a consequence, inversion results that minimize this data misfit may become erroneous. To mitigate the errors introduced by the incorrect and preestimated sources, an embedded procedure that updates sources along with medium parameters is necessary for the inversion. So far, such a procedure is still missing in the context of WRI, a method that is, in many situations, less prone to local minima related to so-called cycle skipping, compared with FWI through exact data fitting. Although WRI indeed helps to mitigate issues related to cycle skipping by extending the search space with wavefields as auxiliary variables, it relies on having access to the correct source functions. To remove the requirement of having the accurate source functions, we have developed a source-estimation technique specifically designed for WRI. To achieve this task, we consider the source functions as unknown variables and arrive at an objective function that depends on the medium parameters, wavefields, and source functions. During each iteration, we apply the so-called variable projection method to simultaneously project out the source functions and wavefields. After the projection, we obtain a reduced objective function that only depends on the medium parameters and invert for the unknown medium parameters by minimizing this reduced objective. Numerical experiments illustrate that this approach can produce accurate estimates of the unknown medium parameters without any prior information of the source functions.
Microseismic monitoring of Vaca Muerta completions in the Neuquén Basin, Argentina
Authors: Curia David , Duncan Peter M. , Grealy Michael , McKenna Jon , Hill Andrew
Published: March 2018

The Vaca Muerta shale oil play in Argentina's Neuquén Basin is expected to make a large contribution to Argentina's hydrocarbon production in the future. In 2013, the U.S. Energy Information Administration estimated that the Vaca Muerta had technically recoverable reserves of 308 Tcf gas and 16 billion bbl of oil and condensate, making it the third largest shale oil reservoir in the world at that time. Wintershall Energia has been active in the Neuquén Basin since 1994. In 2014, it acquired a controlling interest in the Aguada Federal block with an intention to exploit the Vaca Muerta oil shale occurrence within that block. At the outset of its development program, Wintershall decided to incorporate microseismic monitoring to help understand completions in the Vaca Muerta. Monitoring of the completion of vertical well AF.x-1 was accomplished with a surface array. The goal of the monitoring was to inform later decisions on horizontal wellbore direction, wellbore and stage spacing, and landing depth. Results of the surface array monitoring were also used in the design of a permanent buried array intended to monitor subsequent development wells. The buried array was installed in September 2016 and consists of 126 stations spread at an interval distance of approximately 500 m over an area of roughly 5 by 7 km. Each station has geophones placed over a depth range of 20 to 50 m subsurface. The first two horizontal development wells in the project, AF.x-4h and AF.x-9h, were completed in late December 2016 and early January 2017. The second set of two wells, AF.x-3h and AF.x-7h, was completed from May to June 2017. The 4h and the 7h were landed in the upper Middle Vaca Muerta while the 9h and 3h were drilled about 100 m deeper, landing still in the Middle Vaca Muerta. The lateral length of each well was approximately 1000 m, and each was completed with 11 plug-and-perf stages. Stage length and interval were varied along the wells to test various completion strategies. The completions of all four wells were successfully monitored using the buried array. These microseismic data provide a detailed description of the fracture network created by the treatments. Focal mechanisms determined for the detected events have been used to understand the stress distribution in the reservoir and to further refine the completion parameters for future development wells.
Deepwater slope valley reservoir architecture and connectivity, Brazil
Authors: Fowler James Nathan , Novakovic Lydia
Published: March 2018

A detailed interpretation was undertaken to improve the description of connectivity and reservoir distribution for a field in the Campos Basin, Brazil. The Miocene reservoir was deposited in a deepwater, channelized turbidite fairway in a slope valley setting. Static pressure data acquired after production start-up indicated communication across the reservoir, but the values varied significantly, implying that the efficiency of communication varies. High-quality 3D seismic in combination with production and well data led to a hierarchical interpretation, from channel element to complex-set scale, which defined key stratigraphic and pressure surfaces. Integration of a high-repeatability 4D monitor survey showed that the 4D response changed at stratigraphic boundaries. The 4D data tied to production indicate that an aquifer is traveling along the base of the reservoir in discrete channels. The use of 4D depth shift data increased confidence in the waterfront interpretation in areas without production data. Aggradational channel complexes in the upper part of the reservoir show baffling at the margins of channel complexes down to the channel element scale. The channel elements are also likely baffled on the margins with greater connectivity downward into the lower, amalgamated unit. The lower unit shows greater lateral continuity in 4D signal, consistent with pressure data that indicate larger depletion over greater distances than the overlying aggradational complexes where producer wells are located. In summary, mapping of reservoir architecture and identification of key stratigraphic surfaces from 3D have reduced uncertainty in reservoir distribution and connectivity. Integration of 4D seismic and production data has provided confirmation of connectivity through the identification of waterfronts and unswept areas of the reservoir.
Translating In Vivo Metabolomic Analysis of Succinate Dehydrogenase–Deficient Tumors Into Clinical Utility
Authors: Casey Ruth T. , McLean Mary A. , Madhu Basetti , Challis Benjamin G. , ten Hoopen Rogier , Roberts Thomas , Clark Graeme R. , Pitfield Deborah , Simpson Helen L. , Bulusu Venkata R. , Allinson Kieren , Happerfield Lisa , Park Soo-Mi , Marker Alison , Giger Olivier , Maher Eamonn R. , Gallagher Ferdia A.
Published: March 2018

Purpose

Mutations in the mitochondrial enzyme succinate dehydrogenase (SDH) subunit genes are associated with a wide spectrum of tumors, including pheochromocytomas and paragangliomas, GI stromal tumors, renal cell carcinomas, and pituitary adenomas. SDH-related tumorigenesis is believed to be secondary to accumulation of the oncometabolite succinate. Our aim was to investigate the potential clinical applications of proton-1 magnetic resonance spectroscopy (1H-MRS) in a range of suspected SDH-related tumors.

Patients and Methods

Fifteen patients were recruited to this study. Respiratory-gated single-voxel 1H-MRS was performed at 3T to quantify the content of succinate at 2.4 ppm and choline at 3.22 ppm.

Results

A succinate peak was seen in six patients, all of whom had germ line SDHx mutations or loss of SDHB by immunohistochemistry. Succinate peaks were also detected in two patients with metastatic wild-type GI stromal tumors and no detectable germ line SDHx mutations but with somatic epimutations in SDHC. Three patients without tumor succinate peaks retained SDHB expression, consistent with SDH functionality. In six patients with borderline or absent peaks, technical difficulties such as motion artifact rendered 1H-MRS difficult to interpret. Sequential imaging in a patient with a metastatic abdominal paraganglioma demonstrated loss of the succinate peak after four cycles of [177Lu]DOTATATE, with a corresponding biochemical response in normetanephrine.

Conclusion

This study has demonstrated the translation into clinical practice of in vivo metabolomic analysis using 1H-MRS in patients with SDH-deficient tumors. Potential applications include noninvasive diagnosis and disease stratification, as well as monitoring of tumor response to targeted treatments.
The Impact of Postreperfusion Syndrome on Acute Kidney Injury in Living Donor Liver Transplantation: A Propensity Score Analysis
Authors: Jun In-Gu , Kwon Hye-Mee , Jung Kyeo-Woon , Moon Young-Jin , Shin Won-Jung , Song Jun-Gol , Hwang Gyu-Sam
Published: March 2018

BACKGROUND:

Postreperfusion syndrome (PRS) has been shown to be related to postoperative morbidity and graft failure in orthotopic liver transplantation. To date, little is known about the impact of PRS on the prevalence of postoperative acute kidney injury (AKI) and the postoperative outcomes after living donor liver transplantation (LDLT). The purpose of our study was to determine the impact of PRS on AKI and postoperative outcomes after LDLT surgery.

METHODS:

Between January 2008 and October 2015, we retrospectively collected and evaluated the records of 1865 patients who underwent LDLT surgery. We divided the patients into 2 groups according to the development of PRS: PRS group (n = 715) versus no PRS group (n = 1150). Risk factors for AKI and mortality were investigated by multivariable logistic and Cox proportional hazards regression model analysis. Propensity score (PS) analysis (PS matching and inverse probability of treatment weighting analysis) was designed to compare the outcomes between the 2 groups.

RESULTS:

The prevalence of PRS and the mortality rate were 38% and 7%, respectively. In unadjusted analyses, the PRS group showed more frequent development of AKI (P < .001), longer hospital stay (P = .010), and higher incidence of intensive care unit stay over 7 days (P < .001) than the no PRS group. After PS matching and inverse probability of treatment weighting analysis, the PRS group showed a higher prevalence of postoperative AKI (P = .023 and P = .017, respectively) and renal dysfunction 3 months after LDLT (P = .036 and P = .006, respectively), and a higher incidence of intensive care unit stay over 7 days (P = .014 and P = .032, respectively).

CONCLUSIONS:

We demonstrated that the magnitude and duration of hypotension caused by PRS is a factor contributing to the development of AKI and residual renal dysfunction 3 months after LDLT.
The Pursuit of Happiness
Authors: Williams Bianca C.
Published: March 2018

In The Pursuit of Happiness Bianca C. Williams traces the experiences of African American women as they travel to Jamaica, where they address the perils and disappointments of American racism by looking for intimacy, happiness, and a connection to their racial identities. Through their encounters with Jamaican online communities and their participation in trips organized by Girlfriend Tours International, the women construct notions of racial, sexual, and emotional belonging by forming relationships with Jamaican men and other "girlfriends." These relationships allow the women to exercise agency and find happiness in ways that resist the damaging intersections of racism and patriarchy in the United States. However, while the women require a spiritual and virtual connection to Jamaica in order to live happily in the United States, their notion of happiness relies on travel, which requires leveraging their national privilege as American citizens. Williams's theorization of "emotional transnationalism" and the construction of affect across diasporic distance attends to the connections between race, gender, and affect while highlighting how affective relationships mark nationalized and gendered power differentials within the African diaspora.
Robotics-inspired biology
Authors: Gravish Nick , Lauder George V.
Published: March 2018

For centuries, designers and engineers have looked to biology for inspiration. Biologically inspired robots are just one example of the application of knowledge of the natural world to engineering problems. However, recent work by biologists and interdisciplinary teams have flipped this approach, using robots and physical models to set the course for experiments on biological systems and to generate new hypotheses for biological research. We call this approach robotics-inspired biology; it involves performing experiments on robotic systems aimed at the discovery of new biological phenomena or generation of new hypotheses about how organisms function that can then be tested on living organisms. This new and exciting direction has emerged from the extensive use of physical models by biologists and is already making significant advances in the areas of biomechanics, locomotion, neuromechanics and sensorimotor control. Here, we provide an introduction and overview of robotics-inspired biology, describe two case studies and suggest several directions for the future of this exciting new research area.
NEW ADVANCED TYPES OF HETEROPTERA, PENTATOMIDAE IN THE KRASNODAR REGION
Authors: Пушня Марина , Pushnya Marina , Снесарева Екатерина , Snesareva Ekaterina , Родионова Елена , Rodionova Elena
Published: March 2018

Based on the analysis of literature data and own observations, the main features of the development of the adventive the brown marmorated stink bug (BMSB) Halyomorpha halys Stal. have been revealed. In order to find effective means of pest control, a number of biopreparations have been screened, as a result of which it has been established that bitoxybacillin, P, produced by Sibbiofarm LLC 82,9-88,3% of insects.
New narrow-beam neutron spectrometer in complex monitoring system
Authors: Михалко Евгения , Mikhalko Evgeniya , Балабин Юрий , Balabin Yuriy , Маурчев Евгений , Maurchev Evgeniy , Германенко Алексей , Germanenko Aleksey
Published: March 2018

In the interaction of cosmic rays (CRs) with Earth’s atmosphere, neutrons are formed in a wide range of energies: from thermal (E≈0.025 eV) to ultrarelativistic (E>1 GeV). To detect and study CRs, Polar Geophysical Institute (PGI) uses a complex monitoring system containing detectors of various configurations. The standard neutron monitor (NM) 18-NM-64 is sensitive to neutrons with energies E>50 MeV. The lead-free section of the neutron monitor (BSRM) detects neutrons with energies E≈(0.1÷1) MeV. Also, for sharing with standard detectors, the Apatity NM station has developed and installed a neutron spectrometer with three energy channels and a particle reception angle of 15 degrees. The configuration of the device makes it possible to study the degree of anisotropy of the particle flux from different directions. We have obtained characteristics of the detector (response function and particle reception angle), as well as geometric dimensions through numerical simulation using the GEANT4 toolkit [Agostinelli et al., 2003]. During operation of the device, we collected database of observations and received preliminary results.
Argentyńsko-amerykańska współpraca militarna w okresie dyktatury wojskowej w Argentynie w latach 1976-1983
Authors: Lisińska Magdalena
Published: March 2018

U.S.‑Argentine military cooperation during the Last Dictatorship, 1976‑1983 The article analyses U.S.‑Argentine military cooperation in the years 1976‑1983. At the time Argentina was ruled by the authoritarian military junta. The first part of the paper presents the broader context of the Argentine‑American cooperation: the circumstances of the seizure of power by the generals in Argentina, characteristics of the Argentine regime, the U.S. response to the 1976 Argentine coup d’état, and the U.S. changing attitude towards the military junta. The second part of the article focuses on the analysis of the U.S. military assistance to Argentina: loans for the purchase of arms, direct financial assistance and signed contracts. The third part of the article elaborates on the two countries’ shared commitment in Central America subregion.
The Offshoring Return Premium
Authors: Hoberg Gerard , Moon S. Katie
Published: March 2018

We use 10-K filings to construct novel text-based measures of the extent to which U.S. firms are exposed to three offshore activities: the sale of output, purchase of input, and ownership of producing assets. Our main result is that selling output abroad is associated with higher stock returns, especially when output is sold to more central nations in the real trade network. In contrast, offshore input serves as a hedge. Our findings are consistent with the conclusion that aggregate quantity shocks are the primary source of the return premium we document in the global trade network.

The online appendix is available at https://doi.org/10.1287/mnsc.2017.2929 .

This paper was accepted by Lauren Cohen, finance.
The Impact of E-book Distribution on Print Sales: Analysis of a Natural Experiment
Authors: Chen Hailiang , Hu Yu Jeffrey , Smith Michael D.
Published: March 2018

Digital distribution introduces many new strategic questions for the creative industries—notably, how the use of new digital channels will impact sales in established channels. We analyze this question in the context of e-book and hardcover sales by exploiting a natural experiment that exogenously delayed the release of a publisher’s new Kindle e-books in April and May 2010. Using new books released simultaneously in e-book and print formats in March and June 2010 as the control group, we find that delaying e-book availability results in a 43.8% decrease in e-book sales but no increase in print book sales on Amazon.com or among other online or offline retailers. We also find that the decrease in e-book sales is greater for books with less prerelease buzz. Together, we find no evidence of strong cannibalization between print books and e-books in the short term and no support for the sequential distribution of books in print versions followed by e-book versions.

This paper was accepted by Lorin Hitt, information systems.
Value Creation Through Employer Loans: Evidence of Informal Lending to Employees at Small, Labor-Intensive Firms
Authors: Hunt Richard A. , Hayward Mathew L. A.
Published: March 2018

At small and medium-sized enterprises (SMEs), cash-strapped employees frequently request loans from employers because they cannot obtain money on reasonable terms elsewhere for exigent needs. In turn, employers decide whether to lend the money through formal (i.e., written, contractual) loans or more informal “off-the-book” (OTB) loans. Our exploration of this understudied source of credit unearths important questions about the reasons employers lend money to employees, the manner in which they decide to make formal or informal loans, and the coveted benefits employers derive from lending to their workers. Considering the pervasiveness and significance of loan choices among small firms, and the absence of studies on the topic, we tackle these questions through an analysis of 459 informal and formal loans issued by 83 small business owners to their employees. The results show that the issuance of OTB loans is a key tactic for employers to manage resource dependencies with valued workers.
Outdoors is always the right place
Authors: Dubiel Jan
Published: March 2018

When it comes to learning opportunities and memorable experiences, there is every reason that the outdoor environment should be an integral part of children's experience in early childhood education.
A real voyage of discovery
Authors: Harries Judith
Published: March 2018

The third in our series exploring practical activities for introducing concepts that will help children in the Understanding the world area of learning – this month, we look at interactive discovery corners.
Impact of Gender and Conference Size on Conference Preferences – Employing Natural Language Processing
Authors: Eckhaus Eyal , Davidovitch Nitza
Published: March 2018

This pilot study focuses on the impact of academic conferences from a gender-based perspective. What motivates faculty members to attend conferences? Which conferences do they choose? Can differences be found between men and women in their attitude to the effect of the conference and its contribution to their academic work, in light of many studies on the significance women attach to the value of family and its prioritization over their career? The study dealt with a case study of one university in Israel. Ninety four academic faculty members from a variety of departments completed a questionnaire, including 60.9% women and 39.1% men. The main finding is that, among both men and women, academic conferences are perceived as contributing to their professional development. Faculty members addressed the contribution of conferences to their professional development. Findings showed that professional focusing during conferences results in publications and develops interest in the conference – and not vice versa, i.e., it is not interest in the conference that leads to publications. It was also found that the size of the conference predicts the significance of the focus on professional aspects. From a gender perspective, women prefer small conferences. In addition, for women, although they prefer small conferences they attach significance to collaborations that lead to professional focusing on their fields of research. Women appear to bring their "family-oriented patterns" to their work, explaining their inclination to small and more intimate conferences. The research findings might have an impact on the consideration given to planning academic conferences in order to reach the academic outcomes expected by faculty members who perceive conferences as an essential platform for their professional development.  
Hamstring autograft size importance in anterior cruciate ligament repair surgery
Authors: Figueroa Francisco , Figueroa David , Espregueira-Mendes João
Published: March 2018

Graft size in hamstring autograft anterior cruciate ligament (ACL) surgery is an important factor directly related to failure. Most of the evidence in the field suggests that the size of the graft in hamstring autograft ACL reconstruction matters when the surgeon is trying to avoid failures. The exact graft diameter needed to avoid failures is not absolutely clear and could depend on other factors, but newer studies suggest than even increases of 0.5 mm up to a graft size of 10 mm are beneficial for the patient. There is still no evidence to recommend the use of grafts > 10 mm. Several methods – e.g. folding the graft in more strands – that are simple and reproducible have been published lately to address the problem of having an insufficient graft size when performing an ACL reconstruction. Due to the evidence presented, we think it is necessary for the surgeon to have them in his or her arsenal before performing an ACL reconstruction. There are obviously other factors that should be considered, especially age. Therefore, a larger graft size should not be taken as the only goal in ACL reconstruction.

Cite this article: EFORT Open Rev 2018;3:93-97. DOI: 10.1302/2058-5241.3.170038
Potential Value of YAP Staining in Rhabdomyosarcoma
Authors: Ahmed Atif A. , Habeebu Sultan S. , Sherman Ashley K. , Ye Shui Q. , Wood Nicole , Chastain Katherine M. , Tsokos Maria G.
Published: March 2018

Rhabdomyosarcoma (RMS) is a common malignancy of soft tissue, subclassified as alveolar (ARMS), pleomorphic (PRMS), spindle cell/sclerosing (SRMS), and embryonal (ERMS) types. The Yes-associated protein (YAP) is a member of the Hippo pathway and a transcriptional regulator that controls cell proliferation. We have studied the immunohistochemical expression of YAP in different RMSs, arranged in tissue microarray (TMA) and whole slide formats. Pertinent clinical data including patient age, gender, tumor location, and clinical stage were collected. Out of 96 TMA cases, 30 cases (31%) were pleomorphic, 27 (28%) were embryonal, 24 (25%) alveolar, and 15 (16%) spindle cell. Positive nuclear YAP staining was seen in the PRMS (17/30, 56.7%), SRMS (7/15, 46.7%), ERMS (19/27 or 70%), and less in ARMS (37.5%). YAP nuclear staining was significantly more prevalent in ERMS than ARMS ( p=0.02). Of the 41 whole slide cases, nuclear staining was detected in all ARMS but was restricted in distribution to <30% of the cells, in contrast to ERMS and SRMS, which had diffuse or >30% staining. These results highlight the role of YAP in RMS tumorigenesis, a fact that can be useful in engineering targeted therapy. Restricted nuclear YAP staining (<30% of cells) may be of value in the diagnosis of ARMS.
Through the lens of a jewellery practice: An inquiry into photographic representation within a practice-based Ph.D.
Authors: Geremia Allison
Published: March 2018

In the context of a practice-based Ph.D. programme, photography plays an important role within the written thesis. Starting from the recognition that both photography and jewellery can be understood as having a dual nature, in that they can both function as subject and object, this article explores how photography can change the physical object. A practitioner of photography and jewellery can create a complex inquiry when engaging with both mediums. This article considers how each medium can be considered a form of practice in its own right and how each has the ability to change presentation and viewership.
A story about a drawing
Authors: Rankovic Katarina
Published: March 2018

This story about a drawing narrates the inner world of the page and its populace of lines, their struggles and their peace, and how all this internal drama hangs contingently on the vast physical and historical world that it is a part of. The story is extrapolated from video essays in which I film myself hurriedly attempting to verbalize fragments of the accelerated decision-making process accentuated by my flitting wrist while drawing. Talking Drawing is a method of historical restoration taking place at the site of the moving hand that questions what its choreographic inheritance has to say about the plethora of semantic decisions explicit in the drawing.

There turned out to be very little I could glean of my hand’s wisdom; it scarcely seems attached to me, so possessed is it by the gestures of other artists, those I have never met and many of whom were dead long before I was born. But just as sagas, which through a few stories retold by narrators excavate a genealogy of Nordic heroes and outlaws, the hand that draws is the hand that lives to tell the tale of those that came before it. The singular drawing as narrative, as history, is considered here as an iteration in an evolution concerning hands, eyes and lines spanning enormous timescales of innumerable individuals. This enormity is emphasized in order to appreciate the economy of a drawing, which contains all this history effortlessly, and whose ingenuity far surpasses my imagination. The following account, both technical and narrative, attempts to locate points at which the pragmatic approach in drawing appears inseparable from semantic concern and meditates on the relationship that these decisions have with the identities of the artist, her ghosts and readers of drawings.
An Approach of Vector Autoregression Model for Inflation Analysis in Indonesia
Authors: Zuhroh Idah , Kusuma Hendra , Kurniawati Syela
Published: March 2018

A control of the inflation rate caused by the fluctuations in foreign exchange reserves, money supply, and exchange rate is required to create the stability of the country's economy. This study aims to analyze the dynamic impact of disturbance factors contained in the variables of foreign exchange reserves, the money supply, and the exchange rate. This research used monthly data from June 2009 to November 2016. It used a method used of Vector Autoregression. The result shows that a foreign exchange reserve has a negative relationship nut not significant effect on inflation, money supply has positive relationship and significant effect on inflation, and exchange rate of rupiah to US dollar has negative relationship and significant effect on inflation. The responce of inflation from shocking occurs to supply, foreign exchange reserves and exchange rate tend to be convergent and the biggest contribution that influences inflation the most is exchange rate beside inflation itself.
Kesetimbangan Energi dan Manfaat dalam Aplikasi Produksi Bersih di Sistem Pengolahan Limbah Cair Industri Nanas Kaleng
Authors: Andarani Pertiwi , Sari Mega Mutiara , Siallagan Afni
Published: March 2018

Industri pengolahan buah umumnya memiliki kadar organik yang tinggi, Salah satunya adalah industri pengolahan nanas. PT Great Giant Pineapple, Lampung, (PT GGP) merupakan produsen nanas kaleng ekspor yang menghasilkan limbah yang berpotensi mencemari lingkungan apabila tidak dikelola dengan baik. Salah satu upaya pengelolaan lingkungan dan perbaikan berkelanjutan, PT GGP berupaya melaksanakan sistem produksi bersih. Produksi bersih merupakan suatu strategi pengelolaan lingkungan yang bersifat preventif dan terpadu yang perlu diterapkan secara terus menerus pada proses produksi dan daur hidup produk dengan tujuan megurangi resiko terhadap manusia dan lingkungan. Tujuan dari penelitian ini adalah untuk menganalisis kesetimbangan energi dan manfaat secara kuantitatif dalam penerapan sistem produksi bersih di sistem pengolahan limbah cair PT GGP. Kesetimbangan energi dianalisis dengan menggunakan indikator NER (Net Energy Ratio) dan NEP (Net Energy Production). Manfaat finansial dari penggunaan kembali sludge juga dievaluasi secara kuantitatif. Dalam produksi biogas jumlah energi input yang dibutuhkan sebesar 1,002 MJ/hari/m3 air limbah, menghasilkan jumlah energi output sebesar 108,587 MJ/hari/m3 air limbah. Sehingga Nilai NER = 108,37 dan NEP = 17,585 MJ/hari/m3 air limbah. Sementara itu, dengan pemanfaatan Sludge atas perusahaan memperoleh keuntungan sebesar Rp 3.326.687.65/hari dan pemanfaatan sludge bawah memperoleh keuntungan sebesar Rp 19.054.592 /hari pada tahun 2015.
Major Advances and Challenges in Heterogeneous Catalysis for Environmental Applications: A Review
Authors: Wacławek Stanisław , Padil Vinod V.T. , Černík Miroslav
Published: March 2018

Heterogeneous catalysis is one of the fastest developing branches of chemistry. Moreover, it is strongly connected to popular environment-related applications. Owing to the very fast changes in this field, for example, numerous discoveries in nanoscience and nanotechnologies, it is believed that an update of the literature on heterogeneous catalysis could be beneficial. This review not only covers the new developments of heterogeneous catalysis in environmental sciences but also touches its historical aspects. A short introduction to the mechanism of heterogeneous catalysis with a small section on advances in this field has also been elaborated. In the first part, recent innovations in the field of catalytic air, water, wastewater and soil treatment are presented, whereas in the second part, innovations in the use of heterogeneous catalysis for obtaining sustainable energy and chemicals are discussed. Catalytic processes are ubiquitous in all branches of chemistry and there are still many unsolved issues concerning them.
Disjunctive clauses with o. o ‘either. or’ in Spanish and clausal cosubordination
Authors: Conti Carmen
Published: March 2018

This paper examines disjunctive clauses marked witho… o‘either… or’ in Spanish with a view to demonstrating that, in contrast to conventional analyses,o… o-clauses are actually cosubordinate:o… o-clauses are [+dependent, ‒embedded], they generally share clausal operators and they often denote an episode or a sequence of events showing some sort of continuity in space as well as participants. To this end, this paper will describe subordinate and coordinate clauses in accordance with several tests and will go on to outline the properties ofo… o-clauses, focusing in particular on their similarities and differences with respect to coordinate and subordinate clauses. Finally, it will describe whyo… o-clauses would be better classified as examples of clausal cosubordination.
Minimizers in Azerbaijani from a comparative perspective
Authors: Suleymanova Venera , Hoeksema Jack
Published: March 2018

Azerbaijani, like many other languages, has a class of negative polarity items denoting minimal measures (along dimensions such as size, length, duration, value, weight etc.), called minimizers. This paper presents an overview of this group of expressions, compares them to minimizers in the western European languages, in particular English and Dutch, identifies the various domains in which these minimizers may be used, and discusses their distribution across polarity-sensitive contexts such as negation, conditional clauses, questions, etc. The distribution we found, on the basis of both corpus data and native speaker judgments, is very similar to that of minimizers in English or Dutch, especially when differences are factored out which are due to the fact that Azerbaijani has strict negative concord, whereas English and Dutch do not. To this end, we distinguish two types of minimizers for Azerbaijani, negated minimizers preceded byheç bir‘not one’, and minimizers preceded bybironly.
The impact of mild hypercholesterolemia on glycemic and hormonal profiles, menstrual characteristics and the ovarian morphology of women with polycystic ovarian syndrome
Authors: Pergialiotis Vasilios , Trakakis Eftihios , Chrelias Charalampos , Papantoniou Nikolaos , Hatziagelaki Erifili
Published: March 2018

Background

The severity of polycystic ovarian syndrome (PCOS) has been clearly associated with insulin resistance, obesity and metabolic syndrome. The purpose of the present cross-sectional study is to investigate whether mild hypercholesterolemia alters the biochemical and clinical profile of PCOS patients.

Methods

Our study is based on a prospectively collected population of women of reproductive age who were diagnosed with PCOS according to the definition of the Rotterdam European Society of Human Reproduction and Embryology/American Society for Reproductive Medicine (ASRM/ESHRE) criteria. For the correlation analysis we used the non-parametric Spearman’s rank correlation coefficient. Partial correlation was also performed to control for potential confounders observed in the univariate analysis.

Results

Overall, 235 patients were included. Their mean age ranged between 14 and 45 years old and the body mass index (BMI) between 17 and 54. Women with mild hypercholesterolemia had a higher BMI and their fasting insulin was increased as well as indices of insulin resistance [Homeostatic model assessment (HOMA), quantitative insulin sensitivity check index (QUICKI), Matsuda index] compared to women with PCOS with normal cholesterol levels. Correlation statistics suggested that the effect of serum lipids on the hormonal profile of patients was weak. Both low-density lipoprotein (LDL) and high-density lipoprotein (HDL) exerted a significant mild negative correlation to glucose and insulin. However, after controlling the results for BMI and age (the two variables that were found significantly different in the univariate analysis) we observed that this effect was non-significant.

Conclusion

Mild hypercholesterolemia does not affect the hormonal profile of patients with PCOS; hence, to date, there is no evidence to suggest its treatment for the correction of menstrual and hormonal abnormalities in PCOS women.
Visceral adipose tissue in patients with severe mental illness
Authors: Kahl Kai G. , Deuschle Michael , Stubbs Brendon , Schweiger Ulrich
Published: March 2018

Background

Severe mental illnesses (SMIs), i.e. major depression, schizophrenia and bipolar disorder, are associated with an elevated risk for the development of type-2 diabetes mellitus and cardiovascular disorders. Several factors have been associated with increased cardiometabolic morbidity and mortality in SMI, including lifestyle factors (smoking, inactivity, unhealthy diet), endocrine and immunologic alterations; however, the underlying mechanisms remain to be fully uncovered. It is now well accepted that visceral adipose tissue (VAT) promotes the development of cardiometabolic disorders, at least in part by inflammatory and metabolic functions.

Methods

This paper reviews studies concerning VAT, with special focus on intra-abdominal and pericardial adipose tissue, in SMI.

Results

In patients with SMI, several studies have been performed concerning VAT. Most of these studies reported alterations of VAT particularly in patients with major depression and schizophrenia, independent of body weight and body mass index. Some of the studies also reported an increased cardiometabolic risk.

Conclusion

Patients with SMI are at increased risk of developing cardiometabolic disorders, and display increased amounts of VAT. As studies so far were mainly performed on patients before the onset of cardiometabolic disorders, VAT may serve as a biomarker for patients with SMI to assess cardiometabolic risks beyond established risk scores. Further, interventions aiming at reducing VAT in SMI are highly recommended in long-term multimodal treatment plans.
Obesity associated disease risk: the role of inherent differences and location of adipose depots
Authors: Hill Jessica H. , Solt Claudia , Foster Michelle T.
Published: March 2018

Obesity and associated metabolic co-morbidities are a worldwide public health problem. Negative health outcomes associated with obesity, however, do not arise from excessive adiposity alone. Rather, deleterious outcomes of adipose tissue accumulation are a result of how adipocytes are distributed to individual regions in the body. Due to our increased understanding of the dynamic relationship that exists between specific adipose depots and disease risk, an accurate characterization of total body adiposity as well as location is required to properly evaluate a population’s disease risk. Specifically, distinctive tissue depots within the body include the lower body, upper body and abdominal (deep and superficial) subcutaneous regions, as well as visceral (mesenteric and omental) regions. Upper body and visceral adipose tissues are highly associated with metabolic dysfunction and chronic disease development, whereas lower body gluteofemoral subcutaneous adipose tissue imparts protection against diet-induced metabolic derangement. Each adipose depot functions distinctly as an endocrine organ hence it has a different level of impact on health outcomes. Effluent from adipose tissue can modulate the functions of other tissues, whilst receiving differential communication from the rest of the body via central nervous system innervation, metabolites and other signaling molecules. More so, adipose depots contain a diverse reservoir of tissue-resident immune cells that play an integral part in both maintaining tissue homeostasis, as well as propagating metabolically-induced inflammation. Overall, the conceptualization of obesity and associated risks needs updating to reflect the complexities of obesity. We review adipose tissue characteristics that are linked to deleterious or beneficial adipose tissue distributions.
Radiant Heat Transfer in Nitrogen-Free Combustion Environments
Authors: Osama A. Marzouk
Published: March 2018

When mathematically calculating the radiant heat flux during combustion, the radiant property of a gaseous mixture can be approximated as a weighted sum of the radiant properties of fictitious gases to give an equivalent effect of the actual gas mixture. This concept has been in use for many years. However, it was initially tailored to product gases in air-combustion environment. With the advent and progress in nitrogen-free combustion (particularly for environmental purposes), the chemical composition of the combustion gases is highly altered and existing models should be assessed for their suitability in these new environments. We carried out this task, which was motivated by our recent modeling work that revealed that a new model should be developed for nitrogen-free combustion environments. The model proposed here has four participating gases plus one transparent gas and its performance in predicting radiant heat transfer in 3D benchmark problems is evaluated in comparison with existing models, using the discrete-ordinate method for directional radiation domain combined with the finite-volume method of the spatial domain.
The relationship between diet quality and insulin resistance in obese children: adaptation of the Healthy Lifestyle-Diet Index in Turkey
Authors: Ertaş Öztürk Yasemin , Bozbulut Rukiye , Döğer Esra , Bideci Aysun , Köksal Eda
Published: March 2018

Background:

Childhood obesity and its complications are serious health problems and diet/lifestyle changes can be beneficial for the prevention of diseases. Adaptation of the Healthy Lifestyle-Diet (HLD) Index in accordance with the dietary guidelines for Turkey (TR) and determination of the relationship between metabolic syndrome risk factors in obese children were the aims of this study.

Methods:

This study was conducted on 164 overweight or obese children (87 male, 77 female) aged 9–13 years. For all participants, the HLD-TR Index and a 24-h dietary recall were performed and the mean adequacy ratio (MAR) was calculated. Anthropometric measurements and the body composition of the children were taken. Metabolic syndrome risk factors and insulin resistance were assessed.

Results:

The mean age of the male and female children was 11.2±1.49 and 11.0±1.40 years, respectively. The majority of the children were obese in both genders. There were no statistically significant differences in the HLD-TR scores between the genders. As the index scores increased, a decrease in the energy intake and an increase in the MAR were observed. Negative correlations between the index scores and body mass, waist circumference and body fat mass were observed. Furthermore, a one-unit increase in the index score decreases the insulin resistance risk by 0.91 times after adjustments for age and gender (odds ratio: 0.91 [0.85–0.97]).

Conclusions:

The HLD-TR Index is a valid tool that can give an idea about the quality of the diet in obese children. Furthermore, with the increase in the compliance with recommendations for diet/lifestyle changes, indicators of obesity and metabolic syndrome were decreased.
HbA1clevels in children with type 1 diabetes and correlation to diabetic retinopathy
Authors: Andreasson Rebecka , Ekelund Charlotte , Landin-Olsson Mona , Nilsson Charlotta
Published: March 2018

Background:

Type 1 diabetes mellitus (T1D) is a metabolic disease causing hyperglycemia due to β-cell destruction. Despite adequate treatment, complications such as diabetic retinopathy (DR) are common. The first aim was to investigate if acute onset of type 1 diabetes differed between those who had developed retinopathy and who had not after 15 years from diagnosis. The second aim was to investigate if mean glycosylated hemoglobin (HbA1c) levels affect the time to development of DR.

Methods:

The medical records of all children and adolescents diagnosed with type 1 diabetes during 1993–2001 in our area in Sweden were studied retrospectively and the mean HbA1ceach year until the development of retinopathy was investigated. In total 72 patients were included and the follow-up time was between 15 and 23 years. Gender, p-glucose, age and HbA1cat diagnosis were analyzed for possible correlations to years to retinopathy.

Results:

HbA1cwas significantly higher among those who had developed DR after 15 years from diagnosis, 98±9.2 (n=25) vs. 86±9.2 (n=46; p=0.025). A negative correlation was found between age at diagnosis and years to DR (rs=−0.376; p=0.026). Mean HbA1clevels at years 6–10 after diabetes diagnosis correlated significantly (rs=−0.354, p=0.037) to years until retinopathy. Mean HbA1clevels at years 1–15 after diabetes diagnosis were significantly higher at years 2–3 and years 5–8 for those who had developed retinopathy after 15 years from diagnosis.

Conclusions:

Higher HbA1clevels shortened the time to development of retinopathy. It is therefore important to keep HbA1cas close to normal as possible.
The De-globalized City
Authors: Haselmayer Sascha
Published: March 2018

Public procurement in cities is one of the most exciting and under-studied governmental processes, offering an interesting angle into the real state of globalization in cities, the political and bureaucratic battle for the identity of government in connected markets and provides an indication of the intention of city governments to work in a globalized or de-globalizing world.

557,000 city and municipal governments procure an estimated 10% of world GDP in goods and services annually to serve their communities. In a perfectly globalized world, we would expect a single market to develop around these needs with competitors differentiating on cost, effectiveness and strategic value.

Yet, after decades of globalizing trends and announcements by Mayors to collaborate on global challenges, we have few indications that this has happened. Instead of rational, standardized transactions to deploy what works best, each procurement carried out by city and municipal governments is a complex battleground of vested local interests, strategic goals and public messaging.

In place of policymaking and adopting proven practices, cities appear simply to muddle through, one transaction at a time. Despite more open governments and transparency, there is a universal lack of data as to how these battles are fought.
Research for the lichen Usnea barbata metabolites
Authors: Bazarnova Yulia , Politaeva Natalia , Lyskova Nadegda
Published: March 2018

This work presents investigations of biologically active metabolites of Usnea barbata lichen. Extraction conditions for usnic acid and other biologically active phytocomponents using various solvent systems were chosen. Modern analytical techniques were used to study composition of the obtained extracts; usnic acid and phenolic compound contents were estimated. Antioxidant activity and antimicrobial properties of lichen dry extract against bacteria Bacillus subtilis and Pseudomonas fluorescens were studied.