bluuebunny/crossref_metadata_2025 huggingface dataset:
Successful application of left radial access for stenting the right internal carotid artery in a patient with multifocal atherosclerosis: A case report
Authors: Khafizov R. , Khafizov T. , Idrisov I. , Abkhalikova E.
Published: October 2019

This article presents a successful clinical case of the endovascular treatment of stenosis of the right internal carotid artery through the left radial access in a patient with multifocal atherosclerosis with the occlusion of both iliac arteries and the right radial artery. Transfemoral access is the conventional access route for carotid stenting. However, this may be problematic because of peripheral vascular disease and numerous anatomical variations of the aortic arch and cervical arteries. Bleeding in the puncture area is the most common complication after carotid artery stenting (CAS) via transfemoral access. The elimination of such complications has been well demonstrated via transradial access in patients undergoing coronary interventions. Thus, transradial access has been evaluated as an alternative strategy for carotid stenting. Currently, the CAS procedure is a fairly routine practice in many centres involved in the treatment of this pathology; however, a small percentage of patients who are contraindicated in carotid endarterectomy who lack standard puncture access to the arteries and have a complex anatomy of the brachiocephalic arteries still remain. In such cases, the question regarding the feasibility of the CAS procedure using non-standard puncture approaches and various techniques for the catheterisation of the brachiocephalic arteries remains relevant. In this case, the left radial access and the Catheter Looping and Retrograde Engagement Technique were used for the catheterisation of the right common carotid artery because of the anatomical features, the patient’s refusal toward carotid endarterectomy, and the lack of standard access (femoral and right radial). A distal protection system was used for the brain.Received 18 July 2019. Revised 15 August 2019. Accepted 19 August 2019.Funding: The study did not have sponsorship.Conflict of interest: Authors declare no conflict of interest.Author contributionsOperator: R.R. Khafizov Collection and processing of material: R.R. Khafizov, I.A. IdrisovWriting original draft: R.R. KhafizovEditing: E.E. Abkhalikova, T.N. Khafizov
Microwave-assisted Single Step Cinnamic Acid Derivatization and Evaluation for Cytotoxic Potential
Authors: Mishra Sonali , Singh Shilpi , Ali Arif , Gupta Amit C. , Shanker Karuna , Bawankule Dnyaneshwar U. , Luqman Suaib
Published: October 2019

Background:

Phenylpropylene biosynthesis pathway plays a crucial role in the vanillin and
their derivative(s) production in the plants. The intermediate of vanillin synthesis i.e. cinnamic acid
(CA) is converted into 2-Hydroxy 4-MethoxyBenzaldehyde (HMB) in Decalepis arayalpathra having
a number of therapeutic value.

Objective :

Microwave-assisted modifications in cinnamic acid were planned for potential anticancer
properties with better yield and efficiency. The present study also confirms the presence of HMB and
its precursor i.e. cinnamic acid in D. arayalpathra tubers.

Methods:

We used a single step Microwave Assisted Synthesis (MAS) to modify cinnamic acid, and
then examined the synthetic and natural cinnamic acid derivatives anticancer potential against six human
cancer (K-562, WRL-68, A549, A431, MCF-7, and COLO-201) and two normal (L-132 and
HEK-293) cell lines at 2, 10 and 50 µg/ml concentrations.

Results:

β-bromostyrene and β -nitrostyrene have shown inhibition with IC50 values ranging 0.10-21
µM and 0.03-0.06 µM, respectively to the cancer cell lines. β-bromostyrene was the most potent anticancer
derivative of CA with better cellular safety and biocompatibility.

Conclusions:

The present study of microwave-assisted synthesis demonstrates a single-step modification
in cinnamic acid. MAS is a fast, reliable, and robust method. The resultant compounds have
shown in-vitro anticancer activity against human lung carcinoma and breast adenocarcinoma.
Phosphatidylinositol 3-kinase Glu545Lys and His1047Tyr Mutations are not Associated with T2D
Authors: Elfaki Imadeldin , Mir Rashid , Abu-Duhier Faisel M. , Khan Roaid , Sakran Mohammed
Published: October 2019

Background:

Insulin resistance initiated in peripheral tissues induces type 2 diabetes (T2D).
It occurs when insulin signaling is impaired.

Introduction:

Phosphatidylinositol 3-kinases (PI3K) are important for insulin signaling. Single nucleotide
polymorphisms of the PI3K gene have been associated with T2D.

Methods:

We have investigated the association of Glu545Lys and His1047Tyr mutations of phosphatidylinositol-
4,5-bisphosphate 3-kinase catalytic subunit alpha (PIK3CA) gene with T2D. We have
screened 103 T2D patients and 132 controls for Glu545Lys mutation, and 101 T2D patients and 103
controls for the His1047Tyr mutation from a Saudi cohort using AS-PCR.

Results:

Our results indicated that there is no association between the GA genotype of rs104886003
(Glu545Lys) and T2D, OR= 0.15 (95% CI: 0.007-3.28), RR= 0.29(0.02-3.72), P value= 0.23. The A
allele is also not associated with T2D diabetes, OR= 1.01(95% CI: 0.70-1.46), RR=1.00(0.85-1.18), P
value=0.91. Results showed that CT genotype of rs121913281 (His1047Tyr) was not associated with
T2D, OR=0.94(95% CI: 0.23-3.9), RR= 0.97(0.48-1.97), P-value = 0.94, and T allele was also not associated
with T2D, OR=1.06 (95% CI: 0.71-1.56), RR= 1.02(0.84-1.24), P-value =0.76.

Conclusion:

We conclude that the A allele of rs104886003 may not be associated with T2D. The T allele
of rs121913281 may also not associated with T2D. However, future studies with larger sample
sizes and in different populations are recommended.
In silico Designing of Novel Inhibitors for Triple Inhibition of Aldose Reductase, Aldose Reductase Like Protein 1, and Aldehyde Reductase
Authors: Devi Arpita
Published: October 2019

Background:

Cancer is a well-known and well-studied disease. There are environmental
as well as genetic factors that trigger cancer. All forms of cancer are associated with the deregulation
of genes and proteins. Aldose reductase, Aldose Reductase like protein 1 and Aldehyde Reductase
are homologous proteins that are overexpressed in different types of cancer. They are NADPHdependent
oxidoreductases. The active site is conserved, thus there is very less substrate specificity
among those proteins. In this study, novel molecules targeting the three proteins are designed.

Methods:

LigBuilder V2 software is used to design novel molecules. Molecular docking is performed
to study the binding affinity of each ligand towards the targets. Molecular Dynamics Simulation
was done to check the stability of protein-ligand complexes in an aqueous environment.

Results:

Six novel molecules have been designed. The six molecules studied are found to have better
in silico affinity than tolrestat (known inhibitor). The designed molecules are predicted to be orally
active. Finally, Molecular Dynamics Simulation showed that the protein-ligand complexes are stable
in an aqueous environment.

Conclusion:

New molecules targeting Aldose reductase, Aldose Reductase like protein 1 and Aldehyde
Reductase have been designed.
Interactions of Flavone and Steroid from A. subintegra as Potential Inhibitors for Porcine Pancreatic Lipase
Authors: Ibrahim Mastura , Abdul Azziz Saripah Salbiah Syed , Wong Chee Fah , Bakri Yuhanis Mhd , Abdullah Fauziah
Published: October 2019

Background:

Obesity is one serious health condition that contributes to various chronic diseases.
The inhibition of pancreatic lipase is a promising treatment for obesity.

Objective:

The present study was designed to investigate anti-porcine pancreatic lipase effect of isolated
compounds from Aquilaria subintegra and its mechanism.

Methods:

Compounds were isolated with serial column chromatography and their structure were identified
using spectroscopic methods. Isolated compounds were tested for anti-lipase potential activity using
colorimetric assay. The prediction of energy binding between isolated compounds and enzyme was
described using YASARA software.

Results:

Four compounds were successfully isolated from the bark of A. subintegra, namely, 5-
hydroxy-7,4’-dimethoxyflavone, luteolin-7,3’,4’-trimethyl ether, 5,3’-dihydroxy-7,4’-dimethoxyflavone
and β-sitosterol. The results indicated that all compounds displayed promising pancreatic lipase
inhibitory activity ranging between of 6% to 53% inhibition. Compound 5-hydroxy-7,4’-
dimethoxyflavone was a competitive inhibitor and decreases the enzyme catalysis. Meanwhile, β-
sitosterol was a non- competitive inhibitor since the latter was bind allosterically toward enzyme.

Conclusion:

This finding is significant for further investigation of bioactive compounds from A. subintegra
on animal study.
Prospects of Wedelolactone as a Chemotherapeutic Agent in Gynecological Cancers; Clue From its In Vitro and In Silico Investigation
Authors: Sarwar Sadia , Amed Tauqeer , Qazi Neelum Gul , Yu Jun Qing , Huq Fazlul
Published: October 2019

Background:

Identification and development of new drug candidates to be used singly or in combination therapy is critical in anticancer research. In recent years, accumulating evidence encouraged us to investigate the anti-proliferative effects of a small and emerging phytochemical Wedelolactone (WDL) in estrogen-dependent and independent multiple gynecological tumor models.

Objective:

The aim of this study was to investigate the growth inhibitory effect of WDL on estrogen- dependent and independent gynecological cell lines and to explore its inhibitory potential towards key targets through in silico study.

Methods:

Cytotoxicity of WDL was investigated in human breast and ovarian cancer cell lines (MCF-7 and SKOV3) through 3-(4,5-Dimethyl-2-thiazolyl)-2, 5-diphenyl-2H-tetrazolium bromide (MTT) reduction assay. Epigallocatechingallate (EGCG) was used as reference natural compound while cisplatin was taken as a standard clinical agent. Both WDL and EGCG in combination with cisplatin were also evaluated for their combined growth inhibitory potential in MCF-7 cells. WDL was also evaluated in silico against key factors including braf kinases, CDPK, ERα, aromatase, topoisomerase II and dihydrofolate reductase (DHFR) playing pivotal roles in driving multiple tumors.

Results and Discussion:

The IC50 value of WDL was 25.77 ± 4.82 μM and 33.64 ± 1.45 μM in MCF-7 and SKOV-3 respectively. The binding energy order was as follows; WDL: DHFR >Braf kinases > CDPK; aromatase > topoisomerase II> ERα > NFkB > alkaline phosphatase; EGCG dihydrofolatereductase (DHFR) > aromatase >CDPK > topoisomerase II > braf kinases > alkaline phosphatase > CDPK > ERα > NFkB.

Conclusion:

We identified WDL as a cytotoxic agent in breast and ovarian tumor models with the potential to inhibit multiple targets in the oncogenic pathway including estrogen receptor ERα, as depicted through its in silico study. Based on our own research findings and from literature evidence, we conclude that further research should be encouraged to investigate different aspects of wedelolactone as an additional agent to be combined with antiestrogen/endocrine therapy.
Health-Related Social Control Influences the Physical Activity of College Students
Authors: Cotter Kelly A. , Mendiola Jennifer A.
Published: October 2019

Objective:

To examine the impact of health-related social control tactics on the physical activity behavior of college students.

Participants:

110 undergraduates (74% women) recorded their naturalistic behavior across eight consecutive days between March and May of 2010.

Methods:

A short-term longitudinal daily diary survey examined daily self-reports of received health-related social control (the direct regulation of a target’s health behaviors by a social partner) and minutes engaged in physical activity.

Results:

Multilevel modeling according to a two-level structure in which observations (Level 1) were nested within individuals (Level 2) revealed that positive social control for exercise (e.g., encouragement) had a positive effect on physical activity participation, both within-persons (intra-individual level) and between-persons (inter-individual level). Negative social control (e.g., nagging) had no effect on physical activity participation.

Conclusion:

The present results suggest that individuals should employ positive social control tactics when attempting to enhance the physical activity behaviors of college students.
Learning through Play: Improving the Reading Skills through the Joyful Phonetics of Pre-School Children
Authors: Taufik Taufik , Suminto Suwarsi , Ibrahim Rahimah , Abdullah Haslinda
Published: October 2019

Objective:

This study examined the role of a joyful phonetic method to improve reading skills of pre-school children in Indonesia.

Materials and Methods:

Forty-seven pre-school children of age 4-5 years are involved in the study. Two criteria were used to select the participants of the study. Criteria included “they could not read” and “had never read”. The Solomon three groups design was used to test the effectiveness of the treatment. There were one intervention group and two control groups. One of the control groups received the treatment and another one did not. Treatment included joyful learning so that participants did not realise that they were actually learning.

Results:

According to data analysis, (1) joyful phonetic improved the reading skills of the experimental group more than the control group 1 and (2) the joyful phonetic improved the reading skills of the control group 2 more than the control group 1. Moreover, it was found that the phonetic, which had been given in the joyful condition, affects the improvement of the reading skills of pre-school children.

Conclusion:

The implication of the study is that the pre-school children would be more focused on the learning if the method has been conducted in a playing nature. Furthermore, pre-school children should be taught to read as they tend to begin their schooling.
Novel Study of Model-Based Clustering Time Series Gene Expression in Different Tissues: Applications to Aging Process
Authors: Ahmadi Farzane , Abadi Ali-Reza , Bazi Zahra , Movafagh Abolfazl
Published: October 2019

Background:

Aging is an organized biological process that is regulated by highly interconnected
pathways between different cells and tissues in the living organism. Identification of
similar genes between tissues in different ages may also help to discover the general mechanism of
aging or to discover more effective therapeutic decisions.

Objective:

Objective: According to the wide application of model-based clustering techniques, the aim is to
evaluate the performance of the Mixture of Multivariate Normal Distributions (MMNDs) as a valid
method for clustering time series gene expression data with the Mixture of Matrix-Variate Normal
Distributions (MMVNDs).

Methods:

In this study, the expression of aging data from NCBI’s Gene Expression Omnibus was
elaborated to utilize proper data. A set of common genes which were differentially expressed between
different tissues were selected and then clustered together through two methods. Finally, the
biological significance of clusters was evaluated, using their ability to find genes in the cell using
Enricher.

Results:

The MMVNDs is more efficient to find co-express genes. Six clusters of genes were observed
using the MMVNDs. According to the functional analysis, most genes in clusters 1-6 are
related to the B-cell receptors and IgG immunoglobulin complex, proliferating cell nuclear antigen
complex, the metabolic pathways of iron, fat, and body mass control, the defense against bacteria,
the cancer development incidence, and the chronic kidney failure, respectively.

Conclusion:

Results showed that most biological changes of aging between tissues are related to
the specific components of immune cells. Also, the application of MMVNDs can increase the ability
to find similar genes.
Assessment of Antibiotic Knowledge Among Final Year Pharmacy Students at Baghdad University
Authors: Mikhael Ehab Mudher , Hasan Mohammed Khudhair , Abdulridha Sama Zaid
Published: October 2019

Background:

Antibiotics are life-saving drugs that if misused lead to antibiotic resistance and consequently to a substantial public health issue. Pharmacists have a major role in ensuring the rational use of antibiotics to prevent antibiotic resistance. This study aimed to assess antibiotic knowledge among final year pharmacy students at Baghdad University.

Methods:

A cross sectional study using a newly developed and validated questionnaire was given for 148 final year (5thstage) students at Baghdad University – College of Pharmacy during November 2016. Only 140 students (response rate 93%) completed the questionnaire. The 10 items-questionnaire consisted of 5 major domains: Antibiotic effectiveness, side effects, resistance, use in specific cases (e.g., during pregnancy and septicemia), and the legal issues of antibiotic dispensing.

Results:

Only 20% of students have good overall antibiotic knowledge. The least knowledge for pharmacy student was in regard to antibiotic side effects and antibiotic resistance at which only 22% and 19% of pharmacists possessed good antibiotic knowledge respectively. Knowledge of student was the best in legal issues of antibiotic dispensing. There was a non-significant difference in antibiotic knowledge between male and female pharmacy students.

Conclusion:

Antibiotic knowledge among pharmacy students at Baghdad University was very poor and less than expected.
Contributing to a Tactile Language: Partners Communicative Accommodation to a Bodily/Tactile modality
Authors: Lindström Caroline
Published: October 2019

This article is based on the master thesis “Contributing to a Bodily/Tactile Language by Transforming Cultural Customs: - A case study of Partners Communicative Accommodations in Socialised Praxises based on a Bodily/Tactile Modality and its Influences on a Bodily/Tactile Culture” (Lindström, 2017). The study is an ethnographic case study, based on a theoretical framework of language and culture. The case study involves a person with congenital deafblindness and ten of his care workers.

A cultural perspective was used as a way to describe the transformation of customs the care workers have to do to accommodate from their seeing/hearing perspective into a shared bodily/tactile modality. The transformation revealed different bodily/tactile strategies that the caregivers used together with the person with congenital deafblindness.

The case study was conducted in a longitudinal perspective using ten video clips within the same case study. The video clips were transcribed and analysed using an applied theme-based analysis in the search for categories and themes that could help reveal the customs and accommodations.    

The results of this study indicated several strategies that the care workers used together with the person with congenital deafblindness to transform customs in visual sign language into a bodily/tactile communication. The strategies consisted of different body alignments, (hand-over-hand) positions, turn taking markers, the directing of hand and bodies in the conversation, touch and positions from the peripheral partner, the use of objects in the conversation, Martin’s body as an articulation place, haptic signals, back and forth articulation, different tempo and rhythm as well as repetitions.  

https://doi.org/10.21827/jdbsc.5.32574
Abbreviations/Acronyms and Neologisms in English and French WhatsApp Communication: A Comparative Study and Implications for Translation
Authors: Samoh Yong Marinus
Published: October 2019

Since the invention of the Internet in 1962 when J. C. R Licklider of MIT presented the first recorded description of the social interactions that could be enabled through networking in his Galactic Network concept, what has come to be known as social media has gained a lot of prominence and momentum in the dissemination of information. Prior to the dawn of the Internet age other communication tools like the telegraph, telephone, radio, and computer had served as precursors. A tool of immeasurable capabilities, the Internet is also a medium for collaboration and interaction between individuals and their computers without regard for geographic location. Other social media tools that have boarded this 20th Century information superhighway wagon include Yahoo co-founded by Jerry Yang and David Filo in 1994, Facebook co-founded mainly by Mark Zuckerbeg in 2004, Twitter by Jack Dorsey in 2006, WhatsApp by Jan Koum and Brian Acton in 2009 and Instagram by Kevin Systrom in 2010. Our focus in this paper is on the use of WhatsApp as a social media tool. Adjudged one of the fastest and easiest to use, people of all walks of life have taken full advantage of it. Our aim in this paper is to examine how it has impacted on the use of English and French by Anglophones and Francophones in Nigeria and Cameroon so far as neologisms and abbreviations are concerned. Our approach which is comparative in nature has as its principal tenet the implications for translation to and from the two languages involved in this study.
Los universales y la distinción lockeana entre las esencias nominales y reales
Authors: Silva Carmen
Published: October 2019

The objective of the paper is to describe the lockean perspective about the universals. The essences of this perspective is modern because it works mainly with two elements: 1) the nature of the language, and 2) the mechanicism. The lockean conjunction of these two elements in relation to the universals problem, became very original.
Dimensión simbólica de la Revolución mexicana vista a la luz de su centenario
Authors: Gutiérrez Castañeda Griselda
Published: October 2019

In this essay, the author studies the Mexican Revolution history and its principles of social justice and republican democracy, through an interesting idea that focus not just in the rational consciousness of the actors, but, primordially in a complex creation process of the reality. Difficult creation that has been showed clear in the revolutionary processes.
¿Cómo hacer de la vulnerabilidad una herramienta para el cambio? Apuntes para repensar la democracia y la vida común
Authors: Gil Silvia L.
Published: October 2019

The current mercanile logic fragiliza the life: while containing no limits for the extraction of profit, destroyed the social bow and produces disposable bodies. Thus, the violence displayed of the differential ways on bodies becomes a quality non-contingent, but structural of the capitalism. Opposite to it, it would be necessary to deny the vulnerability as part of the royal of the existence in favour of the power to defend the life. Nevertheless, we argue that the opposite happens: only admitting it as inherent part of the being - into the sense of his uncompletion and ontological opening - it is possible to sit the bases for the commun-life from other ethical-political criteria, directed to breaking with the inequality and the dispossession. Said differently: the vulnerability turns into a tool for the politics into the measurement into that provides the base to look for new forms of recognition from which to rethink the democracy.
Técnica y fetichismo. Apuntes sobre el primer libro de El Capital
Authors: Torres Gaxiola Andrea
Published: October 2019

This article shows how technology adopts a fetish nature in the capitalist society, in accordance with the argument presented by Marx in the first book of Capital. We pretend to answer the following issue: is the technology of capital neutral? In our view, this argument extends itself to the following elements that appear in capitalism: money, capital, and technology. Base upon the exposition of the fetish argument, we pretend to show the way technology not only enables the labor value law but also becomes its material form. Thus, in contrast to previous techniques, the technology of capital is not neutral, but, as a mediator between capital and labor, it becomes the material form of value, the technical law of value. In capitalism, following the analysis of Marx and Harry Braverman, technology doesn’t precede social relations, it doesn’t develop itself independently from capitalism, but, on the contrary, emerges as a consequence and it is always limited by the needs of capitalism.
A propósito de mundus est fabula: Descartes y la confección del mundo
Authors: Hernández Moreno Jesús Carlos
Published: October 2019

René Descartes’s philosophy has been considered by “philosophical modernity” as a watershed in the evolution of philosophy seen as a “historical entity”. This is because it implies a “re-creation” of “science” where science establishes itself as the reading (and writing) of the “world” which is driven by that “human impulse” is seen as the unmoved judge of knowledge: doubt. But this doubt gives a character of finiteness and limitation to knowledge acquired through natural light, that is, through the ability to compare and distinguish what is in accordance with the explicit or implicit assumptions that condition its action. Thus, given that certainty only makes sense in and for natural light, the “world” that is constructed in the science of Descartes will remain limited to natural light and this science to the fable in which it is told.
Deleuze: la potencia de la literatura
Authors: Grave Crescenciano
Published: October 2019

This essay explores the way Deleuze thinks the literature, in specific from the point of view of certain modern authors. The literature is an event that expresses the life becoming the language. In this becoming it composes an odd syntax that conserves in itself a block of sensations from where it promotes itself the life’s resistance against the control. That’s how, beyond the lived, the literature, proceed from life and its overtaken for it when it shows, from outside the language, the ideas which overflow itself from their formal expression.
La alteridad en María Zambrano
Authors: Rivara Kamaji Greta
Published: October 2019

The text discusses the notion of alterity present in María Zambrano’s El hombre y lo divino. This concept is linked to the notion of piety, that is, to know how to deal with the other and that the Spanish author links with the treatment that the Greek religion maintained with the gods, as the correct way to deal with the divine. Zambrano repositions the ordinary meaning of both concepts, away from their contemporary use, to build a new meaning. This repositioning takes place in the historical context of positivist rationalism, which seeks to be responded with the proposal of the Spanish philosopher of a thought open to the other.
La recepción de Althusser en México: el caso Carlos Pereyra
Authors: Vázquez Alfonso
Published: October 2019

The reception of the thought of Louis Althusser in Mexico took place between 1960 and 1970. The first to assimilate his theory and argue with her was the marxist thinker Adolfo Sánchez Vázquez, who dedicated several essays and a fundamental book: Science and Revolution (Marxism of Althusser) (1978), besides always be a benchmark of constant controversy in most of his books where poses a different interpretation of the marxism of Althusser. Also in the decade of the seventies and eighties, a brilliant student and disciple of Sánchez Vázquez: Carlos Pereyra, published several texts influenced by Althusser thought that led him to critically assimilate many of his thesis, but also to question them when considered insufficient. The aim of this paper is to assess the althusserian influence on the work of Pereyra, particularly in his essays: Politic and Violence (1974), Settings: Theory and History (1979) and The Subject of History (1984).
La globalización: el olvido del dolor del mundo
Authors: Marieta Iñaki
Published: October 2019

The globalization, economic and socio technological contemporaneous phenomenon has its onthological roots in Parmenides. Roots which make it become destiny of the Western world in its metaphysics and technological form, forgetting the essential grief which hides the triumph of the global connectivity. Only the poets’ word can name the fold of such destiny without being eliminated by the metaphysics: condition for Μνημοσύνη to activate the possibility of a new beginning.
La respuesta visual y textual de la Contrarreforma española a la Reforma protestante
Authors: Camarillo Gómez María Del Carmen
Published: October 2019

The protestant schism than to bend Europe in century xvi to implicate a profound political and religious crisis, the answer than Rome and Catholics kingdoms to offer was the Trento Concilium. After them Spain generate many works to know as genre contra reform. Our intention is a make a course between the visual and textual discourses to cross by proposal iconography and iconological to Spain baroque and discourse textual to be treaty the state of reason whose mission was alert to danger a political division and instability that to presented the Protestantism.
Convergencias y divergencias dialécticas en la Antigüedad griega: Platón y Aristóteles frente a los estoicos
Authors: Padilla Longoria María Teresa
Published: October 2019

For Plato, philosophy is essentially dialectical, that is, for the philosopher of Athens, philosophy and dialectic are interchangeable terms. Likewise, the dialectical activity implies in Plato a specific way of carrying on dialogue as a philosophical conversation which requires a method in order to be developed properly that is, scientifically. The Socratic-Platonic originality resides in the fact that with this idea of dialectic is made explicit the essence of the act of philosophizing as a dialogic act par excellence, that is, as a loving and unselfish search for truth which is made jointly and in a transpersonal way.Aristotle shows us a radically different idea of dialectic in relation to his master, because hereduces its importance and we can even say that he demotes it. For the Stagirite, dialectic will be, at the very best, a non-scientific procedure for searching the truth, with no demonstrativecharacter and it will have the purpose of providing general principles to sciences, but it will not be a synonymous with philosophy and therefore of the highest science anymore. Equally, dialogic interchanges based on questions and answers will not be essential at all, neither for particular sciences nor for philosophy itself.The Stoics have a Socratic-Platonic and Aristotelian influence in relation to their idea ofdialectic, but they have their own coinage and they will develop, on this matter, a properproject. For the Stoics, dialectic will be a virtue itself and one cannot become a wise manif one is not a dialectician. Even more: dialectic will play a pivotal and agglutinative rolein the Stoic system as a whole. Thus the central purpose of this article will be to show thesimilarities and differences that the Stoics have in relation to their Socratic-Platonic andAristotelian antecedents regarding the dialectical topic and where do their originality andproper deploys reside.
Los límites de la imagen: ¿representar lo irrepresentable?
Authors: González Valerio María Antonia , Rivara Kamaji Greta
Published: October 2019

This paper deals with the controversies and discussions that many important authors, particularly in France and Germany, have had concerning the question on existence in relation to the extermination of Jews during the National Socialism regime in Germany. The paper discusses and analyzes the possibility of representing what many authors consider to be unrepresentable, focusing on a deep reflecion about images and testimonies in so far as they seem to make possible the impossible, i.e., representing what seems to be unrepresentable.
Justificación, educación y libertad
Authors: Gómez Salazar Mónica
Published: October 2019

This paper argues the thesis that education should be understood as a guide that directs the young people towards reflexive and imaginative social practices that allow them to formulate new and varied hypotheses as well as alternative justifications. Based on Dewey, we will expose that a goal such as this is only applicable to members of a democratic society. Next, we present some features of onto-epistemological pluralism in relation to freedom and responsibility. It is concluded that there is no justification that is closer to truth or reality. The relevance of a justified belief with good reasons lies in its practical consequences for specific conditions of existence.
Bertrand Russell y el pragmatismo
Authors: Laguna Rogelio , Zurita Gonzalo
Published: October 2019

This paper analyzes the two stages of the relationship of the British philosopher Bertrand Russell withpragmatism. The first section reviews the criticisms that the author made to American pragmatists.The second exposes Russell’s pragmatic turn, exposing the causes of this turn and its consequences. This paper argues that both stages should be understood in the context of the discussions about truth that were observed in philosophy in the first decades of the 20th century.
Una posible respuesta de Ch. S. Peirce al problema tradicional de la inducción
Authors: Vázquez Gutiérrez Ricardo
Published: October 2019

Ch. S. Peirce recognizes induction as one of the three moments of the scientific method. This means that he thought that the induction was, in a way, justified. In this paper I intend to review what Peirce’s response might be to the traditional problem of induction, namely, the problem of justifying a general principle of inductive inferences. This principle is traditionally characterized as the Principle of uniformity of nature (PU). Particularly, then, I am interested in evaluating Peirce’s opinion regarding the justification of a PU version, namely, the Principle of regularity of nature (PR). The work is composed of three sections, the first will present a version of the argument that gives rise to the traditional problem of induction; in the second, a reconstruction of the characterization of Peirce’s PRwill be offered; and in the third, it will be reviewed in which way for Peirce the PR could be justified—which would seem to solve Hume’s problem; finally, in the fourth section, as a conclusion, a brief evaluation of this possible answer of Peirce to Hume’s problem will be offered.
“Third Party Funding”; su relevancia e influencia actual en el mundo del arbitraje internacional
Authors: Theoduloz Santiago
Published: October 2019

El presente trabajo tiene como objeto analizar el fenómeno de los Third Party Funding o terceros financistas y su influencia y desarrollo actual en el mundo del arbitraje internacional comercial y de inversión. En base a ello se analizan los principales aspectos y características del fenómeno y las distintas regulaciones existentes en el mundo actual. Asimismo, se estudia como el fenómeno puede influenciar en los estándares de independencia e imparcialidad de los árbitros y como consecuencia de ello en la eventual existencia de conflictos de intereses.
Binuclear copper(II) complexes: Synthesis, structural characterization, DNA binding and in silico studies
Authors: Kamran Abdul , Ali Saqib , Tahir Muhammad , Zahoor Muhammad , Wadood Abdul , Iqbal Muhammad
Published: October 2019

Two new binuclear Cu(II) complexes represented by the general formula {(dmso)Cu(?-L)4Cu(dmso)} (1) and {(Phen)(L)Cu(?-L)2Cu(L)(Phen)} (2) where dmso = dimethyl sulphoxide, L = 2-bromophenyl acetate and Phen = = 1,10-phenanthroline have been synthesized, isolated quantitatively and characterized by UV/Vis and FT-IR spectroscopic techniques, thermogravimetry/ /differential thermal analysis and X-ray single crystal XRD studies. Complex 1 is paddlewheel with 1,2-O,O-bridging while 2 has 1,1-O-bridging. The values of the intrinsic binding constants with DNA were found out to be 2.0?103 and 1.1?103 M-1, respectively for compound 1 and 2. The mode of interaction of complexes with DNA was also evaluated through computational study by molecular docking (in silico) study using molecular operating environment (MOE) software. The synthesized complexes are structurally as well as biologically important.
Frankel 2 appliance versus the Modified Twin Block appliance for Phase 1 treatment of Class II division 1 malocclusion in children and adolescents: A randomized clinical trial
Authors: Campbell Ciara , Millett Declan , Kelly Niamh , Cooke Marie , Cronin Michael
Published: October 2019

Objective:

To compare Phase 1 treatment, using the Frankel 2 (FR2) or the modified Twin Block (MTB), for Class II division 1 malocclusion in children and adolescents with respect to: treatment duration, number of appliance breakages, occlusal outcome, and patient and parent perspectives.

Materials and Methods:

Sixty participants with a Class II division 1 malocclusion were randomly assigned to either the FR2 or MTB appliance in a two-armed parallel randomized clinical trial with an allocation ratio of 1 to 1. Time to achieve a Class I incisor relationship was the primary outcome. The number of appliance breakages was recorded. The Peer Assessment Rating (PAR) index was used to evaluate pre- and post-treatment occlusal outcome on study models. Participants completed the child OHRQoL (oral health-related quality of life), Piers-Harris, Standard Continuum of Aesthetic Need (SCAN), and Oral Aesthetic Subjective Impact Score (OASIS) questionnaires pre- and post-treatment; parents completed a SCAN questionnaire.

Results:

Forty-two participants completed treatment (FR2: 20; MTB: 22). Multiple imputation was used to impute missing data for noncompleters. Mean treatment duration was similar for the two appliances (FR2: 376 days [SD 101]; MTB: 340 days [SD 102]; P = .41). There were no significant differences in mean number of appliance breakages (FR2: 0.3 SD 0.7; MTB: 0.4 SD 0.8; P = .67 or mean PAR score P = .48). Patient and parent perspectives did not differ between appliances (P > .05).

Conclusions:

Phase 1 treatment duration, number of appliance breakages, occlusal outcome, and patient and parent perspectives were similar in 11–14 year olds with Class II division 1 malocclusion treated using the FR2 or MTB appliance.
Assessing the accuracy of two posterior tooth-size discrepancy prediction methods based on virtual occlusal setups
Authors: Fallis Drew W.
Published: October 2019

Objective:

To assess accuracy of the Bolton and Johnson/Bailey (JB) analyses in identifying clinically significant posterior tooth-size discrepancies using virtually constructed occlusal setups.

Materials and Methods:

Virtual models and cone-beam computed tomography data sets from 30 patients were utilized to construct 60 (two per patient) virtual posterior occlusal setups. Observed discrepancies in cusp-embrasure relationships were compared to estimated posterior interarch tooth-size discrepancies (ITSDs) calculated via Bolton and JB posterior analyses. Clinical significance for discrepancies was established at >1 mm from ideal cusp-embrasure relationships in accordance with current American Board of Orthodontics methodology. Data within groups were normally distributed, thus comparisons were completed via paired t-tests. Paired nominal data were analyzed utilizing McNemar's test, and simple linear regression was used to model the relationship of predicted to observed discrepancies.

Results:

McNemar's test revealed significant differences (P ≤ .05) between the Bolton and JB groups' frequencies in matching the virtual setups correctly. JB predictions matched 100% (right) and 97% (left) setups; whereas, Bolton predictions matched only 23% (right and left) setups. A positive correlation was observed between JB predictions and cusp-embrasure discrepancies, demonstrating that average posterior discrepancy values increased 0.28 mm for every 1 mm predicted via the JB analysis.

Conclusions:

The JB analysis correctly characterized, but overestimated, the degree of posterior ITSDs corresponding to a clinically significant discrepancy in the virtual setups. Algebraically calculated posterior ITSDs based on the Overall and Anterior Bolton ratios were not accurate predictors of discrepancies observed in the virtual setups. Both Bolton and JB demonstrated weaknesses that limit precise identification of clinically significant ITSDs.
KAJIAN PSIKOLOGI BELAJAR: MENGUKIR PRESTASI MELALUI PENGENALAN DIRI DAN OPTIMALISASI POTENSI
Authors: Purwandari Eny
Published: October 2019

Self knowledge is a process which must be conceded by everyindividual. In this process, it is likely that an individual knows his strengthand weakness. The strength does not always cause benefit, on the otherhand the weakness does not always cause a misplace. However, if bothof them are managed well, it will cause something extraordinary. Thestudent has to know his self knowledge to get the best achievement.  Someof the things that should be considered are: style of learning, emotionand the ways of life orientation. For the students of MAN I Sragen, thelearning style tends to be auditory. They manage their emotion well enough,and their ways of life are focused on three things namely: spirit, familyharmony, and achievement. Based on the result of social service, thestudents and the teachers have to use and maximize it well so that theirpositive potential can be optimized and developed well either individuallyor collectively in the educational institution.
Pelatihan Pemanfaatan Web Bagi Pemuda Muhammadiyah Cabang Kartasura
Authors: Fatmawati Azizah
Published: October 2019

Web is one medium that can be used by many activists in communityorganizations to actualize themselves and communicate effectively. Web UtilizationTraining for Muhammadiyah Youth in Kartasura branch is expected to provideknowledge into the importance of mastering Information Technology and increasethe understanding of the web (Web Logs) as the more effective information tool (AmarMa’ruf Nahi Munkar). The result shows that the implementation of the training isquite successful. This can be seen from the enthusiasm of the participants in providingfeedback from the questionnaires delivered before and after the training. Furthermore,the training also shows an increasing knowledge in the use of the web as much as64%.
PENGEMBANGAN PRODUKSI PESTISIDA ALAMI DARI Beauveria bassianaDAN Trichoderma sp. MENUJU PERTANIAN ORGANIK
Authors: Purnama Herry , Hidayati Nur , Setyowati Eni
Published: October 2019

Recently the condition of agriculture in Indonesia needs to be addressed. Soil fertility getting damaged due to chemical fertilizer that is not impartial. In addition, the impact of excessive use of synthetic pesticides can cause damage to the ecosystem. Control of plant diseases using biological agents began getting attention because of public concerns due to the use of synthetic chemical pesticides. Biological agents are microorganisms,  both  naturally  occurring  such  as  bacteria,  fungi,  viruses  and protozoa, as well as the results of genetic engineering that are used to control plantpests. Madrasah Diniyah Jumapolo, Karanganyar, has pioneered the manufacture of biological agents to support organic farming although on a small scale. Community service activities undertaken to provide assistance in the improvement of the production process  and  management  improvements.  The  technology  developed  is  the  use  ofbiological pesticides agent isolated from Beauveria bassiana and Trichoderma sp. As a natural insecticide and fungicide. The activities received support from the madrasa and expressed successfully produce biological agents in the proper packaging. In addition to the consumption of madrasa and nearby farmers, pesticide product ofbiological agents is also sold to the public. The selling of products will increase the development of organic farming to produce healthy food also will gain additional income for the madrasa.
IbM PENGEMBANGAN KEPROFESIAN BERKELANJUTAN (PKB) GURU-GURU MIM WILAYAH NGAWEN DAN KLATEN UTARA BERBASIS KURIKULUM 2013
Authors: Rahmawati Laili Etika , Santosa Joko , Muhroji Muhroji
Published: October 2019

The society service has aimed at accompanying the teachers on understanding and conducting the program of sustainable professionalism development (PKB) based on curriculum 2013. When the society service program has finished conducted, it is expected to acquire the four goals as follow: (1) the emergence of a professional teacher group and acquire the teaching competence by implementing the active learning strategy with scientific approach based on curriculum 2013; (2) the learning devices based on curriculum 2013; (3) the research proposal is classroom action research; and (4) the scientific publication article. The method applied in the society service program was conducted with the same model as the PLPG program conducted but the program implementation was simpler or could be called as mini PLPG. The program activity was beginned by deepening of material activity which related to the concept of PKB and the concept of curriculum 2013. The concept of PKB emphasized on three points that should be developed by the teachers, they were the self development, scientific publication, and innovative work. The concept of curriculum 2013 has priority on the changing understanding of the paradigm and the basic concept of curriculum structure, the prominent were about the core and the basic competences. After the deepening materials which conducted in the first phase has finished, the activity then continued by the workshop of the learning devices which emphasized on the concept of scientific approach, the active learning, and the authentic assessment which followed by peer teaching activity. The worshop activity of learning devices was conducted by facilitating the teachers in arranging the learning scenario based on the materials determined. The peer teaching activity was conducted by divide the participants into some groups to conduct the teaching practice by turns and apply the scientific approach. The third phase was the arranging the academic writing, and it has the priority on the arranging of classroom action research (PTK). The teachers were assigned to propose the classroom action research title based on the problem emerged on their classroom. After the teachers have determined the title, the society service team divisible the job to accompany the teachers in arranging the classroom action research. The strategy used in conducting the third phase, the society servicec team acted as the consultant. By the strategies applied, it is expected that the teachers would be more directed in writing and arranging the classroom action research in order to produce the quality academic writing.
PAKOM PELATIHAN DAN PENDAMPINGAN PENYUSUNAN PERANGKAT PEMBELAJARAN MATEMATIKA BERBASIS LESSON STUDY
Authors: Khotimah Rita Pramujiyanti
Published: October 2019

Guru yang profesional adalah salah satu faktor penentu keberhasilan proses belajar mengajar di kelas. Kemampuan merancang perangkat pembelajaran yang berkualitas menunjukkan kesiapan guru dalam mengajar. Tujuan dari kegiatan ini untuk meningkatkan kemampuan guru matematika SMA/SMK Muhamamadiyah Klaten dalam mengembangkan Rencana Pelaksanaan Pembelajaran (RPP)  melalui pendekatan lesson study.Metode pelaksanaan melalui Sosialisasi, pelatihan dan pendampingan. Hasil pelaksanaan kegiatan: (1) ada peningkatan kemampuan guru-guru matematika di SMA/SMK Muhammadiyah Klaten dalam hal mengembangkan perangkat pembelajaran matematika berbasis lesson study(2) Respon peserta terhadap pelaksanaan kegiatan sangat baik.