bluuebunny/crossref_metadata_2025 huggingface dataset:
REMODELING OF THE AERO-HEMATIC LUNG BARRIER COMPONENTS UNDER HIGH ALTITUDES
Authors: Matvienko Viktor Vasil'evich , Abdumalikova Inobat Abdusattarovna , Shidakov Yusuf Khadzhi-Makhmudovich , Margaryan Artur Vanushovich , Zakharchuk Ol'ga Viktorovna , Istomina Ol'ga Fridrikhovna , Shidin Vladimir Aleksandrovich , Tulekeev Tokhtogazy Imanalievich
Published: March 2023

The aim of the study is to examine structural and ultrastructural aero-hematic barrier (AHB) changes in rats during adaptation to high-altitude hypoxia.
Materials and Methods. The experiments were carried out on 60 sexually mature outbred laboratory male rats weighing 140–160 g at high altitude (3200 m above sea level). The authors followed Mayer's hematoxylin and eosin staining protocol, and used transmission and scanning electron microscopy on the 7th, 15th and 30th days of the animals' life in the mountains. Statistical data processing was carried out using Statistica 6.0 (USA) and StatTech v. 2.8.4 (Russia) and Student's t-test. Differences were considered statistically significant at p<0.05.
Results. At early stages of high-altitude adaptation, dystrophic changes in the epithelial layer of lung capillaries, hypertrophy and hyperplasia of histiocytes, fibroblasts and lipofibroblasts were noted. The authors also revealed proliferation of type II alveolocytes, thickening of the interalveolar septa (IAS) and cytoplasmic processes of endotheliocytes, destruction of type II alveolocytes (apocrine method, with the release of surfactant into the alveoli lumen), multivesicular lamellar bodies in the cytoplasm of type II alveolocytes; interstitial edema with transudate in the alveoli lumen. In later periods, surfactant system activity decreases due to a reduced release of osmiophilic lamellated corpuscles (OLC) into the alveoli lumen. The main AHB components are next to control data, while the IAS thickness exceeds the norm. In the alveoli wall, the number of fibroblasts increases, causing an increase in the number of Kohn's pores and providing collateral breathing.
Conclusion. The study of AHD components in experimental animals at different periods of high-altitude adaptation revealed dystrophic processes of AHD in IAS, compensated by type I alveolocytes and proliferation of type II alveolocytes, confirming the adaptive mechanisms of ultrastructural alteration of all epithelial and endothelial components of the pulmonary alveoli.
INTERVAL HYPOXIC HYPEROXIC TREATMENT IN THE REHABILITATION OF POST-COVID-19 PATIENTS
Authors: Ivanov Anatoliy Betalovich , Borukaeva Irina Khasanbievna , Abazova Zalina Khasanovna , Misirova Indira Alievna , Bizhoeva Liana Kazbekovna , Ligidova Diana Ramazanovna
Published: March 2023

The aim of the study is to reveal the main pathogenetic mechanisms of the effectiveness of interval hypoxic hyperoxic treatment in the rehabilitation of post-COVID-19 patients.
Materials and Methods. Hypo-Oxy, hypoxic therapy device produced by Oxyterra (Russia) was used to generate a hypoxic mixture with different oxygen content. Hypoxic periods followed the hyperoxic ones (30 % O2). To determine individual sensitivity to hypoxia, patients underwent a hypoxic test, the results of which were used to select the optimal oxygen content in the hypoxic mixture, the duration of hypoxic effects and the number of sessions. The authors determined the parameters of the functional respiratory system, oxygen regimen, lipid peroxidation, antioxidant system, exhaled air condensate and coagulation system. Statistical processing was carried out in accordance with the rules of mathematical statistics using Microsoft Excel and Statistica 6.0 for Windows. When conducting parametric analysis, paired and unpaired Student's t-tests were used. All numerical data were presented as the arithmetic mean and standard error of the mean (M±m). Differences were considered statistically significant at p<0.05.
Results. Interval hypoxic hyperoxic treatment has proven to be an effective way to rehabilitate post-COVID-19 patients (medium severity). After hypoxic therapy, there was a decrease in respiratory, circulatory, hemic and tissue hypoxia, and an improvement in the parameters of the prooxidant and antioxidant systems. Hypoxic therapy had a normalizing effect on the hemostasis system: platelet count in the blood increased (p<0.05) (it was low before hypoxic therapy). Activated partial thromboplastin time, international normalized ratio, and antithrombin III content also increased. Prothrombin index, fibrinogen and D-dimer content in the blood serum showed a decreased risk of thrombosis.
Conclusion. The conducted studies have proven the high efficiency of interval hypoxic hyperoxic treatment in the rehabilitation of post-COVID-19 patients.
RENAL CONTINUUM: CLASSIFICATION PROBLEMS
Authors: Shutov Aleksandr Mikhaylovich , Efremova Elena Vladimirovna , Menzorov Maksim Vital'evich
Published: March 2023

Disease classification is one of the most serious challenges in modern medicine. New data on disease etiology, pathogenesis, diagnosis, treatment and prognosis lead to the revision of existing principles for the classification of pathological conditions. This is also true about kidney disease. In renal continuum, the first three months from the disease onset are defined as acute kidney injury or acute kidney disease. Chronic kidney disease implies renal structural or functional damage which is observed for more than three months, or markers of kidney damage, regardless of etiology. Despite the apparent simplicity of the renal continuum, there are difficulties in diagnosing and determining the event sequence. Currently, there is no consensus on the place of acute kidney disease in the renal continuum. Therefore, despite high prevalence acute kidney disease is rarely diagnosed, included in the diagnosis or taken into account while assessing the patient prognosis. The authors propose a new classification of renal continuum, which allows us to clarify the criteria for acute kidney disease and acute kidney injury. The suggested classification can be easily used in routine clinical practice. The introduction of biomarkers into wide clinical practice and the clarification of the criteria for acute kidney injury do not affect the proposed classification, but only clarify the criteria for diagnosing acute kidney injury, acute kidney disease, and chronic kidney disease.
LIPOSOMAL TECHNOLOGIES FOR SILYBIN DELIVERY TO THE LIVER IN PATIENTS WITH NON-ALCOHOLIC FATTY LIVER DISEASE
Authors: Pavlov Chavdar Savov , Turankova Taisiya Alekseevna , Varganova Dar'ya Leonidovna
Published: March 2023

The aim of the study is to evaluate the effectiveness and safety of liposomal technologies in the treatment of non-alcoholic fatty liver disease (NAFLD) using Silybin (Lipoliv) as an example.
Materials and Methods. The authors conducted a randomized placebo-controlled study approved by the ethics committee. The study included 111 subjects with NAFLD, aged 18–65. Lipoliv therapy (experimental group) or placebo therapy (control group) lasted for 12 weeks, the trial subjects received 1 capsule per day. The authors evaluated success rates, such as steatohepatitis activity (AST, ALT), severity of liver steatosis (transient elastography with controlled attenuation parameter), quality of life(SF-36 questionnaire); and safety profile: adverse events. Statistical analysis was carried out using the StatTech v. 1.2.0.
Results. The subjects of the experimental group demonstrated a significant decrease in ALT (p<0.001) and AST (p<0.001) levels as well as in steatosis (p<0.001) after treatment. There was a significant improvement in the parameters of physical and mental well-being in both groups (p<0.001). No adverse reactions or therapy interruption were noted.
Conclusion. When treating patients with NAFLD, the effectiveness of Silybin, synthesized with liposomal technologies (Lipoliv), was confirmed by a significant decrease in steatohepatitis activity, improved quality of life, and a decrease in steatosis severity. The drug demonstrated a high safety profile.
PATHOGENESIS OF AUTONOMIC AND PERIPHERAL NEUROPATHY IN PATIENTS WITH PSORIASIS
Authors: Mashina Mariya Vladimirovna , Nesterov Aleksey Sergeevich , Belova Lyudmila Anatol'evna
Published: March 2023

There is enough data confirming the common mechanisms of damage to the nervous system and skin in psoriasis. Cardiac autonomic denervation is a mechanism of cardiovascular pathology in psoriasis. Thus, a simultaneous disturbance of sympathetic and parasympathetic impact on vascular tone and heart rhythm has been established. When performing an active orthotest in trial subjects, heart rate centralization and decreased autonomous circuit activity were found. In psoriasis, vegetative-vascular dystonia develops due to metabolic disorders that occur in diabetes mellitus. Inflammatory cytokines Th-1, adhesion molecules, and angiogenic factors are involved in pathological processes in obesity, diabetes, metabolic syndrome, and thrombotic complications. Microangiopathy, which develops in psoriasis, reduces the response of blood vessels to autonomic innervation. Such negative influences eventually lead to a persistent alteration of the autonomic nervous control. The authors resent the results of a few studies on the peripheral nervous system in patients with psoriasis. There is evidence of a symmetrical alteration of vibration, tactile, pain and temperature sensitivity in the distal regions of all four limbs. There are some histological studies of the sural nerve in patients with psoriasis, which indicate demyelination of nerve fibers. In this regard, the study of neuropathy pathogenesis in psoriasis is necessary to improve the disease course and the effectiveness of psoriasis therapy.
Assessment of psoriatic lesion severity and timely detection of cardiac denervation will reduce the risk of fatal cardiovascular complications. Instrumental diagnostics of the peripheral nervous system will make it possible to differentiate damage to muscle and nerve fibers in psoriasis.
ENDOTHELIN-1 LEVEL IN BLOOD AND LUNG TISSUE IN POST-COVID-19 PATIENTS WITH NON-SMALL CELL LUNG CARCINOMA
Authors: Kit Oleg Ivanovich , Frantsiyants Elena Mikhaylovna , Kharagezov Dmitriy Akimovich , Surikova Ekaterina Igorevna , Goroshinskaya Irina Aleksandrovna , Bandovkina Valeriya Akhtyamovna , Cheryarina Natal'ya Dmitrievna , Shikhlyarova Alla Ivanovna , Pogorelova Yuliya Aleksandrovna , Ayrapetova Tamara Georgievna , Lazutin Yuriy Nikolaevich , Milakin Anton Grigor'evich , Leyman Igor' Aleksandrovich , Stateshnyy Oleg Nikolaevich
Published: March 2023

Long-term consequences of COVID-19 are associated with persistent endothelial dysfunction, so it is important to study both infectious and oncological processes.
The aim of the study was to examine endothelin-1 (ET-1) level in the blood and lung tissues of post-COVID-19 patients (men and women) with non-small cell lung carcinoma (NSCLC).
Materials and Methods. We examined 60 patients (59.1±3.9 years of age) with verified NSCLC, T1-3NxM0, hospitalized at the National Medical Research Center for Oncology in 2020–2021. All patients had a history of asymptomatic/mild COVID-19 (control group) or severe/moderate COVID-19 (main group). We also examined 15 healthy people (of the same age and sex) who did not suffer from COVID-19 at the time of blood sampling (donor group). The levels of endothelin-1 (ET-1-38, ET-1-21) were measured by ELISA in blood plasma of all trial subjects and in lung tissues these parameters were measured only in NSCLC patients before treatment.
Results. In NSCLC patients of the main group, ET-1-21 level in plasma was on average twice as high as that in the control group and in donors. In the tumor and the perifocal zone, ET-1-21 level was higher than that in the resection line tissue: by 1.4–2.7 times in the control group, by 1.6–7.6 times in the main group in men and women. At the same time, women of the main group had a significantly more pronounced increase in ET-1-21 level in the perifocal zone and a decrease in the tumor tissue compared to that in the control group. ET-1-38 level in the control group was 3 and 2.1 times as low as in the tumor and perifocal zone, and in the main group it was 2.8 times as high in the perifocal zone in women as that in the resection line tissue. Gender differences in ET-1 level in both groups of patients were revealed.
Conclusion. In NSCLC post-COVID-19 patients, changes in the endothelin-1 level were found, which could be caused not only by long-term endothelium dysfunction, but which also could modify NSCLC development.
Razvoj, kontinuitet i novosti crkvenog nauka o ratu i naoružanju. Od pravednog rata do teorije o nuklearnom odvraćanju
Authors: Singbo Odilon-Gbènoukpo
Published: March 2023

Katolička Crkva u svojem je moralnom nauku uvijek imalana umu humanitarne posljedice koje uzrokuje svaki rat neovisnoo tome iz kojeg je razloga vođen. Mnogi crkveni mislioci stoga surazvili razne teorije povezane s regulacijom ratnih akcija kao štoje pravedni rat, zakonita obrana i nuklearno odvraćanje. Te teorijeu okrilju crkvenog nauka valja shvatiti u povijesnom kontekstunjihova razvoja i geopolitičkih zbivanja trenutka. Suvremenieksponencijalni razvoj tehnologija primijenjen u industrijama zaproizvodnju oružja znatno otežava mogućnost ostvarenja mira zakojim čeznu svi narodi i svaki pojedinac. Koristeći se raznim teološko-filozofskim izvorima autor u radu obrazlaže teoriju pravednograta počevši od sv. Augustina, Tome Akvinskog do crkvenog učiteljstva.U fokusu je stavljena proizvodnja oružja, položaj kršćanau toj proizvodnji s propitkivanjem njezine etičnosti počevši od Drugogavatikanskog koncila do pape Franje. Posebna je pozornostposvećena tehnicističkomu mentalitetu koji izaziva razne mirovnei etičke izazove. Konkretnom primjenom nekih etičkih načela kaošto su izvori moralnosti ljudskog čina, čin s dvostrukim učinkom,načelo neprotuslovlja ističe se potreba za odgojem za nenasilje irazoružanjem ljudskih srca.
Nanomaterials for Fighting Multidrug-Resistant Biofilm Infections
Authors: Rotello Vincent M.
Published: March 2023

Multidrug-resistant bacterial infections represent a dire threat to global health. The development of antibiotic resistance in bacteria coupled with the lack of development of new antibiotics is creating infections requiring antibiotics of last resort, and even some infections for which we have no available treatment. Biofilm-based infections present some of the most challenging targets for treatment. The biofilm matrix provides a physical barrier that can impede access of antibiotics and antimicrobials to resident bacteria. The phenotypic diversity found in biofilms further exacerbates the difficulty of eliminating infections, with quiescent “persister” cells evading therapeutics and re-initiating infections after treatment. Nanomaterials provide a tool for combatting these refractory biofilm infections. The distinctive size regime and physical properties of nanomaterials provide them with the capability to penetrate and disrupt biofilms. Nanomaterials can also access antimicrobial pathways inaccessible to conventional antimicrobials, providing a synergistic strategy for treating biofilm infections. This review will summarize key challenges presented by antibiotic resistance and biofilms when treating infection and provide selected examples of how nanomaterials are being used to address these challenges.
Pengembangan Instrumen Kemampuan Pemecahan Masalah Matematika Peserta Didik Di SMA
Authors: Idrus Talib , Pomalato Sarson W. , Ismail Sumarno , Mohidin Abdul D.
Published: March 2023

When a teacher conducts an assessment of the ability of students to solve problems, a good test instrument is needed. However, in reality there are still many teachers who use test instrument without going through an expert assessment process, causing the assessment of student learning outcomes to be less than optimal. The purpose of this study was to produce a test instrument for high school students' mathematical problem solving abilities. The type of research used was Research and Development (RD). The sample used was students of SMA N 1 TAPA class XI IPA with a total of 100 people. The Thiagarajan, Semmel, and Semmel (4D) development model was used in this research. The research was divided into 3 stages of the development procedure (preliminary study stage, development stage, and testing stage). The results of the study show that the resulting instrument is valid, with CVR and CVI = 1 and has a high level of reliability (0.77). Based on the results of the implementation of the test instrument in the field trial class, it showed that the assessment of student learning outcomes was more optimal, which was obtained if students' mathematical solving abilities were quite optimal even though there were still indicators that were included in the less category. By developing this test instrument, it will optimize teacher assessment in assessing student learning outcomes, especially in solving math problems.
Konya’da Aile Sağlığı Merkezlerine Başvuran Yetişkinlerin Su Tasarrufu ile İlgili Bilgi, Tutum ve Davranışları
Authors: UYAR Mehmet , KASAPOĞLU Enes , DEMİR Gizem Sena
Published: March 2023

Bu çalışma, Konya ili merkez Meram ilçesindeki aile sağlığı merkezlerine başvuran yetişkin bireylerin su tasarrufu ile ilgili bilgi, tutum ve davranışlarını saptamayı amaçlamıştır. Çalışma; kesitsel tipte bir epidemiyolojik araştırma olarak planlandı ve basit rastgele yöntemle belirlenen beş aile sağlığı merkezinde yürütüldü. 230 kişi araştırma kapsamına alındı. Çalışmaya dahil edilen 230 katılımcının yaş ortalaması 38,28 bulundu. Katılımcıların %90,4’ü dünyadaki su kaynaklarının tükenebileceğini; %66,5’i ülkemizin su sıkıntısı çeken bir ülke olduğunu, %89,6’sı ülkemizin gelecekte su sıkıntısı çekebileceğini ve %70,0’ı su tasarrufu konusunda sorumluluğun bireylere ait olduğunu belirtti. Bahçeli evde yaşayanların aylık su faturası ortalaması anlamlı olarak yüksek bulundu. “Su ayak izi kavramını duyanların yaş ortalaması daha düşük ve eğitim düzeyleri daha yüksek bulundu. Evliler ile üniversite mezunu olanlar; ev aletleri alırken su tasarruflu olmasına daha fazla dikkat etmekteydi. Katılımcıların çoğunun ülkemizin halen su sıkıntısı çektiğini ve gelecekte de su sıkıntısı çekeceğini düşünüyor olmalarına rağmen su tasarrufu konusunda alabilecekleri önlemleri yeterince almıyor oldukları görüldü. Su tasarrufu konusunda alınabilecek önlemlerle ilgili halka eğitim verilmesi, halkın duyarlılığını artırıcı faaliyetler yapılması, gri su kullanımının ve su tasarrufu sağlayacak sistemlerin ve gereçlerin özendirilmesi önerilebilir.
Ebelik Bölümü Öğrencilerinin “Ebe” ve “Ebelik Mesleği” Kavramlarına Yönelik Metaforları
Authors: YEŞİL Yeşim , APAK Hıdır
Published: March 2023

Amaç: Ebelik, hayatın en kritik anlarında bilim, sanat ve etik değerleri bütünleştiren bir meslektir. Ebe ve ebelik mesleği kavramının geleceğin sağlık profesyonelleri tarafından nasıl anlaşıldığı önemlidir. Bu bağlamda, araştırmanın amacı ebelik bölümü öğrencilerinin ‘ebe’ ve ‘ebelik mesleği’ kavramına ilişkin sahip oldukları algıları ve anlam dünyasında nerede durduğunun metaforlar aracılığıyla ortaya çıkarmaktır.
Materyal ve metod: Araştırma nitel araştırma yöntemi ve olgu bilim deseninde yürütülmüştür. Araştırmanın çalışma grubunu 2021-2022 öğretim yılının bahar döneminde öğrenim gören Mardin Artuklu Üniversitesi Ebelik bölümü öğrencileri oluşturmuştur. Araştırmanın verileri her öğrencinin, “Ebe, Ebelik mesleği/ ... gibidir/benzemektedir. Çünkü,...” cümlesini tamamlamasıyla elde edilmiştir. Araştırmaya 89 gönüllü öğrenci katılmıştır. Veriler içerik analizi ile çözümlenmiştir.
Bulgular: Araştırmanın sonuçlarına göre öğrenciler ebe kavramına yönelik 39, ebe mesleğine yönelik 53 farklı metafor üretmişlerdir. Ebe metaforları “kutsal”, “ailenin bir üyesi”, “rehber”, “güçlü”, “yardımcı”, “çok yönlü” şeklinde altı kavramsal tema altında toplanmıştır. Ebelik mesleği ise “yol gösteren”, “spiritüel”, “ihtiyaç duyulan”, “kadim”, “çok yönlü” şeklinde beş tema altında açıklanmıştır.
Sonuç: Ebelik mesleği anne ve bebek sağlığını geliştirmede temel bir disiplin olduğu için öğrencilerin ebe ve ebelik mesleği algıları oldukça önemlidir.
Perceived Organizational Support, Job Insecurity, Organizational Trust toward Organizational Citizenship Behaviour in manufacturing industries of Malaysia
Authors: Hong Liang , Zainal Siti Rohaida Mohamad , Miaoling Zhang
Published: March 2023

Objective - The COVID-19 epidemic has significantly impacted organisational citizenship behaviour (OCB) among Malaysian industrial employees. This study investigates the influence of perceived organisational support (POS) on OCB using job insecurity and organisational trust as mediators.
Methodology/Technique - Adopt the cross-sectional design with the aid of a questionnaire to collect data from 189 selected employees of manufacturing industries in Malaysia. The PLS-SEM technique is used in this study to test the proposed hypotheses.
Findings – The results show that POS directly impacts OCB, and this relationship is also strongly mediated by job insecurity and organizational trust. The manufacturing industries are growing stable on a good workplace climate, including decreasing job insecurity and increasing organizational trust. Moreover, the prior study concentrated on good OCB behavioural results. However, there are also detrimental behavioural consequences that may be impacted by POS, such as unproductive behaviour; therefore, the current research focuses on new variables as mediators, such as job insecurity and organizational trust to fill the research gap.
Novelty - Therefore, Organisational trust and job insecurity further mediate the relationship between POS and OCB. Thus, this paper finds an answer to human resource management (HRM) practices, explaining how POS influences organisational trust and job insecurity towards OCB. The study can help management better understand the importance of OCB in introducing and implementing POS through the improvement of organisational trust and job insecurity in the organisation. Implications and future research directions are discussed.

Type of Paper: Empirical
JEL Classification: D2, E24.
Keywords: Perceived Organizational Support (POS); Organizational Citizenship Behaviour (OCB): Job Insecurity (JI); Organizational Trust (OT); Manufacturing Industry; Malaysia
Reference to this paper should be made as follows: Hong, L; Zainal, S.R.M; Miaoling, Z. (2023). Perceived Organizational Support, Job Insecurity, Organizational Trust toward Organizational Citizenship Behaviour in manufacturing industries of Malaysia, J. Mgt. Mkt. Review, 8(1), 01 – 08. https://doi.org/10.35609/jmmr.2023.8.1(1)
Managing Heutagogy during COVID-19 Pandemic via Virtual Learning and its impact on Academic Identity Status and Communities of Practice (COP)
Authors: Mumin Mas Ayu , Valdez Nena Padilla
Published: March 2023

Objective - The main objective is to examine the experience using a hauntological approach during an online learning phase on fresh undergraduates during the pandemic and to determine undergraduates’ Academic Identity Status (AIS) and awareness of Communities of practice (COP).
Methodology - The respondents are 34 first-year undergraduate students at the university via mixed methods that comprised of classroom observations, online questionnaires, and online interviews.
Findings –The results show that respondents were not ready to embrace heutagogy and virtual learning affected the respondents’ academic identity status and their awareness of their Community of Practice (COP)
Novelty - The paper addresses new findings in experiences of using a hauntological approach during the COVID-19 pandemic and its impact on academic identity status and COP awareness. The implication of this study suggests the need to develop a conceptual framework for a hauntological approach that could be accustomed to a large classroom and a virtual platform.

Type of Paper: Empirical
JEL Classification: I23, I29
Keywords: Pandemic; online learning; Academic Identity Status; Communities of Practice; Heutagogy.
Reference to this paper should be made as follows: Mumin, M.A; Valdez, N.P. (2023). Managing Heutagogy during COVID-19 Pandemic via Virtual Learning and its impact on Academic Identity Status and Communities of Practice (COP), J. Mgt. Mkt. Review, 8(1), 45 – 62. https://doi.org/10.35609/jmmr.2023.8.1(6)
EMPIRICAL ANALYSIS OF VALUE-MOTIVATIONAL ORIENTATIONS OF EMPLOYEES OF EDUCATIONAL ORGANIZATIONS UNDER CONDITIONS OF UNCERTAINTY
Authors: Obukhova N.I.
Published: March 2023

The presented article is an intermediate result of a study conducted in 2022 in the Udmurt Republic, which was aimed at studying the conditions that affect the value-motivational orientations of employees of educational organizations in conditions of uncertainty. Relevance. Modern conditions, characterized by the complex uncertainty of the political and socio-economic situation, make it obvious that there is a need to develop management issues and the possibility of influencing the value-motivational orientations of citizens, including those involved in the educational process. Difficult situations and complex circumstances affect the choice of life attitudes, which can be transformed under the influence of changes. In this regard, an attempt to determine the bottlenecks of the educational industry in the region for making managerial decisions seems relevant. Goal. To substantiate the influence of socio-economic and political conditions on the transformation of value-motivational orientations of employees of educational organizations of the general education system of the Udmurt Republic in conditions of uncertainty. Methodology. The theoretical and methodological basis of the study was the development of domestic and foreign researchers in the field of studying the value, semantic orientations of a person. A quantitative two-phase survey of employees of educational organizations was carried out. The sample size in the first phase of the study was 5220 people, in the second - 1332 people. The results of the research showed that the value-motivational guidelines of the teaching community of the Udmurt Republic are the regulator of group and individual behavior, and also represent life principles that determine goals, attitudes, quality and implementation of life plans. The attention of state and regional management to personal value-motivational orientations of employees of educational organizations is important and expedient for improving organizational policy. Programs for continuous monitoring of managerial decisions on the industry management, which should be taken on the basis of the results of sociological research, will help to solve many existing problems of educational practices and reduce management industry risks in the region.
THE PRACTICE OF “CANCEL CULTURE" IN THE SYSTEM OF INTERNATIONAL RELATIONS OF THE 1960s–1980s
Authors: Beloshapka N.V.
Published: March 2023

This article examines the facts and circumstances of the cancellation of various cultural events due to geopolitical events in the second half of the 1960s and the first half of the 1980s. Examples of the active application of the principle of "cultural boycott" during the Cold War are "Czechoslovak" and "Afghan" factors. There seems to be no need to dwell on the causes and dynamics of the political crises themselves. The paper examines their influence on the emergence of a kind of crisis of cultural diplomacy, expressed primarily in the emergency cancellation of tours, as well as refusal to participate in major international competitions and festivals. Since the cases used in the analysis relate primarily to the application of the "cultural boycott" in relation to the USSR, the article also examines the issue of actions on the part of the bodies responsible for the sphere of culture in the USSR to overcome the isolation of the country in the context of curtailing interstate cooperation with the United States and European countries. An analysis of the practice of canceling cultural events due to the deterioration of relations against the background of political and military crises showed that with a general decline in the level of cultural cooperation, not all countries resorted to a direct boycott of already planned cultural events. In addition, in the absence of official agreements on cultural cooperation, international contacts continued to be maintained at the level of agreements of the USSR Ministry of Culture with various informal and public organizations of foreign countries. Attempts by the Ministry of Culture, as well as leading creative unions to establish contacts bypassing the official authorities, often faced active resistance from the latter. The study of a number of documents shows that creative and public organizations in Western countries experienced significant pressure from their governments and other official structures. When studying the stated topic, a comparative approach was used, as well as such methods of scientific and political analysis as analogy, extrapolation and the case-study method.
Factors Affecting Digital Government Adoption: Empirical Study of Trust and Social Influences on Extended TAM
Authors: Liu Dawei
Published: March 2023

This research is conducted to propose a conceptual model for the adoption of digital government services based on an extended technology acceptance model. Through a survey of 359 users of digital government services, how to operationalize and test emerging variables is investigated to understand citizens' acceptance intentions. The results indicate that perceived social influence and trust are key factors in the acceptance of online government services and intention for adoption. Familiarity and ubiquitous connection have a substantial impact on social influence. Therefore, valuable insight into factors that practitioners prioritize when adjusting their approaches for better results is required. Thus, the adoption of digital government services needs to be related to the level of trust and social influence.
Thrash-streaming as a form of online aggression: a criminal law analysis
Authors: Rakhmanova Ekaterina , Berestovoy Andrey , Tsvetkov Pavel
Published: March 2023

Social networking is one of the most widespread forms of modern digital technologies today. Along with the undoubted advantages of interaction and communication between people on the Internet, the social network generates certain criminological risks, including those associated with the manifestation of various forms of deviant behavior and the creation of a new subculture. Socio-political tensions, economic problems, a decline in the general cultural level, media aggression, the Covid-19 pandemic, as well as the impersonality of the internet and its capabilities contributed to the emergence and rapid spread of online aggression. Netizens have transferred their values and personal problems to the virtual space. One of the manifestations of this deviant behavior is the trash streaming, which has not yet been legally defined. The media abounds with examples of violence, insults, humiliation of human dignity, harm to life and health committed during live broadcasts on the internet. The public and legislators have drafted a bill to amend and supplement the criminal law, proposing to criminalize the commission of such acts online. This article aims at exploring these legislative initiatives and proposals. The authors were therefore faced with the tasks of formulating a general concept of this phenomenon and analyzing the existing scientific literature and the bill criminalizing this negative phenomenon. The authors applied content analysis and general scientific methods, in particular, comparison, analysis and synthesis, statistical and deductive methods, which made it possible to formulate some general conclusions. The authors consider possible objective and subjective features of the act in question and make a conclusion about the need for additional work on the bill, taking into account, inter alia, the opinion of the scientific community.
Social and psychological climate in Internal Affairs bodies’ service teams: an approach to its conceptualisation
Authors: Sitnikov Valeriy , Dukhnovsky Sergey , Korzunin Vladimir
Published: March 2023

Analysis of the socio-psychological climate of the police teams of the internal affairs bodies of the Russian Federation is an important source of information to assess the readiness of employees to perform service tasks.

The problem that initiates the study is the discrepancy between the methods for measuring the climate and the specifics of interaction of employees, the nature and conditions of their work activities. In a domestic social psychology there are dozens of approaches to the understanding of the essence of this phenomenon, methods of its diagnosis and ensuring an optimal climate in the team, which significantly complicates the activities of heads and psychologists of departments of internal affairs. The article is devoted to reconceptualization of the phenomenon of social-psychological climate in law-enforcement bodies teams as in modern conditions the necessity of concrete definition of the phenomenon is evident, without which the tools and procedures used for its measurement cannot be defined and improved. The authors name the key reasons that require in-depth theoretical study of the climate of service teams.

The research methods are cognitive methods of information processing (generalization, systematization and classification), which allow to characterize and synthesize the specifics of the study of the sociopsychological climate.

Results. The article identifies the basic structural elements of the phenomenon under study and describes the main directions of understanding the phenomenon of social and psychological climate. Their specification allows us to adequately assess the modality and level of psycho-social climate, identify the causes of its deterioration in a particular unit and provide adequate psychological support.
The principle of inevitability of criminal responsibility and issues of its exemption
Authors: Zorina Elena
Published: March 2023

The article is devoted to the consideration of the implementation of the principle of the inevitability of criminal liability at the institute of exemption from criminal liability. The relevance of the topic is caused by the wide practice of applying norms on exemption from criminal liability and, as a result, the controversy that has been going on for several years in scientific area about the advisability of consolidating the above principle in the criminal legislation of Russia. The purpose of the work is to study the relationship between the principle of inevitability of criminal liability and the institution of its exemption, its implementation in the specified criminal law institute. In addition, using logical-legal, comparative-legal, structural and statistical research methods, the study analyzes various points of view of legal scholars on the

designated problem, indicates the relationship of this principle with some other principles of criminal law in this criminal law institute. The author concludes that the criminal law institute under consideration and the above principle do not contradict each other, the former principle being a continuation of the latter. The inevitability of responsibility should be taken precisely through the prism of solving a crime, which allows to combine harmoniously the principle under the study and the institution of exemption from criminal liability in the current criminal law. In order to improve the effectiveness of the exemption of criminal liability from criminal law norms in the context of its inevitability, the article gives the author’s proposals for improving criminal law norms.
Augmenting The Cloud Environment Security Through Blockchain Based Hash Algorithms
Authors: MOTUPALLI RAVI KANTH
Published: March 2023

Many techniques and algorithms are developed to enhance the security in the cloud environment. This helps the users to secure their server from malicious attacks. Hence the study and investigation of the performance enhanced security algorithms is a must demanded field in the research industry. When large number users using same server to store their information in cloud environment security is a must needed component to preserve the privacy and confidentiality of every individual user. This can be further strengthened by detecting the attacks in earlier stages and taking countermeasure to prevent the attack. Thus securing the data network without any leakage and loss of the information is a challenging task in the cloud environment. When the attacks or intrusion is detected after the occurrence there may be damage to the data in the form of data damage or theft. Hence it is necessary to predict and detect the attacks before the occurrence to protect the privacy and confidentiality of the user information.

Keywords: Cloud security; Data privacy; Data confidentiality; Hash Algorithm; Substitutional encryption
Comparison of an effectiveness of artificial neural networks for various activation functions
Authors: Florek Daniel , Miłosz Marek
Published: March 2023

Activation functions play an important role in artificial neural networks (ANNs) because they break the linearity in the data transformations that are performed by models. Thanks to the recent spike in interest around the topic of ANNs, new improvements to activation functions are emerging. The paper presents the results of research on the effectiveness of ANNs for ReLU, Leaky ReLU, ELU, and Swish activation functions. Four different data sets, and three different network architectures were used. Results show that Leaky ReLU, ELU and Swish functions work better in deep and more complex architectures which are to alleviate vanishing gradient and dead neurons problems but at the cost of prediction speed. Swish function seems to speed up training process considerably but neither of the three aforementioned functions comes ahead in accuracy in all used datasets.
Usability analysis of advertising websites interfaces with the use of the universal design principles
Authors: Marciniec Jan , Kondraciuk Dominik
Published: March 2023

The aim of the research was to observe how the usage of the universal design principles influences on the accessibility and usability of websites. As one of the analysis’ subjects there was chosen the popular advertising website. It has been confronted with a newly implemented application offering the same functions, but improved with the requirements resulting from the universal design. In order to compare those two services there was conducted the study with the use of eye-tracking, LUT checklists and WAVE Evaluation Tool. These methods made it possible to demonstrate the differences between websites caused by the contrasting implementation methods. The results showed that an application of universal design principles has a positive impact on the websites’ accessibility and usability.
The analysis of Blender open-source software cloth simulation capabilities
Authors: Kogut Wojciech
Published: March 2023

This article explores Blender open-source software capabilities in the area of cloth simulations. Simulation performance with different scene complexity and quality settings is tested with a script that automates the testing. System resource utilization is measured and the appearance of visual artifacts is taken into consideration. Cloth simulation features of Blender are compared to commercial software.
التحليل والتركيب في اعمال الخزافة روث داكورث
Authors: م. فاروق عبد الكاظم غانم
Published: March 2023

تبحث دراستنا واحدة من التحولات المهمة في فن الخزف قبيل وبعد الحربالعالمية الثانية متمثل بنتاج الخزافة ( روث داكورث ) والأثر الذي أحدثته في الخزفعلى مدى قارب السبعين عاماً من الأبداع و الإنتاج المتواصل ءوالمنجز الواسع هذا منفتحعلى العديد من الدراسات واحدها موضوع بحثنا الحالي في رصد وكشف كيفية اشتغالاليات التحليل والتراكيب في فنها ‏ و تناولت الدراسة في فصلها الأول هذه الإشكالية 9والحدود الزمانية والمكانية والموضوعية والتعريف الإجرائي للمصطلحات في البحثكما أسس الفصل الثاني البناء الفكري والمعرفي لمفهوم التحليل والتركيب وبنائيات العملالفني واهم المؤشرات الموضوعية التي اسفر عنها تناول هذه المفاهيم في المصادروالأدبيات كما شمل الفصل الثالث مجتمع البحث و اختيار عينات ممثله لتجارب ووضعفيها اليات التحليل و التراكيب وتحليلها على وفق مؤشرات الاطار النظري ؛ وأخيرااستعراض نتائج التحليل في الفصل الرابع ومناقشة نقاط الفعل المؤثر في توجيه الياتالتحليل والتركيب سواء في جانبه الذهني التخيلي أو جانبه الإظهاري
المسافة الجمالية في مسرح الطفل
Authors: أ.م.د.حبيب ظاهر حبيب
Published: March 2023

البحث في المسافة الجمالية في العرض المسرحي الموجه للطفل يعني بحثا فيعملية التفاعل بين العرض والمتلقي/الطفل. ويفضي بالنتيجة إلى معرفة أهمية المسافةالجمالية والتحكم بمداها. ويتحدد مدى الاندماج/ الانفصال في العرض المسرحي علىوفق أسلوب المخرج ومعالجته ورؤيته الطفولية للنص والإمكانات الإنتاجية المتاحة.البحث يسلط الضوء على كيفية الفصل بين الواقعي والخيالي في العرض المسرحيالموجه للطفل، وذلك لأن الطفل كمتلقي أكثر حاجة من الراشد لمسافة جمالية واضحةالأبعاد خلال تلقيه الفنون والآداب عموماء والعرض المسرحي بصورة خاصة لأنهعرض حي ومباشر.
بناء وحدة نعليمية نمطية في مادة المسرح المدرسي
Authors: د. رغد زكي غياض  , غسان كاظم العبودي
Published: March 2023

إن التطور العام للحياة يفرز عادة الحاجة إلى كثير من العلمية في إعداد جيل قادرعلى استيعاب مهمات الحياة الجديدة وكما شهد العراق تطوراً في كل مجالات الحياة ضشهد ميدان التربية والتعليم تطورا كبيرا وواضحاً في مؤسساته التعليمية إذ لم يعد التعليممحصورا بين جدران المدارس ولم يكن مقتصرا على أشكال التعليم الصفي بل توسعوأصبح للمتعلم دور بارز في العملية التعليمية . وصار لزاماً عليه الاعتماد على نفسه فياكتساب المعلومات والمهارات التي تساعده في حياته العملية .

والطرائق التدريسية التقليدية تحقق لها الثبات النسبي الذي أصبحت تتلقاه منالمؤسسات التعليمية والأوساط التربوية إلا أن ما يحدث من تغيير مستمر في البيئةالتربوية وما يتصل بها ويؤثر فيها كازدياد الطلب على التعلم والتطور المعرفي وغيرهايحتم على ذوي الاختصاص من التربويين إعادة النظر في الأساليب التدريسية على الرغممما تحقق لها من ثبات وأستقرار نسبيين وذلك للوقوف على مدى فاعلية هذه الأساليب فيظل تلك المتغيرات . (
Los medicamentos biosimilares como medicamentos esenciales: reflexiones éticas y legales
Authors: Noguera Peña Alfonso , Del Castillo Rodríguez Carlos
Published: March 2023

El presente artículo recapacita sobre las reformas normativas acontecidas en las últimas décadas respecto al uso racional de los medicamentos, y las medidas operadas en torno a la disminución del gasto farmacéutico. En este contexto, debe destacarse el elevado coste de las terapias biológicas y las dificultades de acceso a las mismas —especialmente en los países en vías de desarrollo—.
Los medicamentos biosimilares son poseedores de garantías sanitarias análogas —semejantes o equivalentes— a los medicamentos de referencia, pero no están sometidos a una protección por una patente y facilitan la accesibilidad a los pacientes, así como al reparto equitativo de los recursos terapéuticos. Además, algunos de ellos están incluido en la lista de medicamentos esenciales de la Organización Mundial de la Salud (OMS).Asimismo, se examina el papel de los medicamentos biosimilares como esenciales y la posibilidad de mejorar el acceso equitativo a estos recursos sanitarios a través de la prestación farmacéutica.
Mudanças históricas no papel social de substâncias entorpecentes e a construção do regime internacional criminalizante
Authors: Morales David , De Souza Gonçalves Higor
Published: March 2023

The current international regime of control over the commerce of psychotropic substances holds a strong criminal approach and has been target of debates regarding its feasibility due to the consequences it’s been causing on different social scopes. Having the objective of enhancing that debate, this article discusses the traditional uses of the term “drug” for then analyzing the different social roles attributed to those substances in different socio-political contexts, including the unfolding of conflicts related to their commerce and use. It is equally intended to understand how the criminal regime has been built, verifying the interests and factors which have helped its consolidation in the contemporary international system. The research demonstrates that the substances under control today have been implemented to execute a range of social roles and not only as being sources of crime. Therefore, the current criminal configuration is not the only one possible and thus there is a possibility of making room to discuss over its restructuring. Furthermore, it was observed that the international criminal regime has been developed supported by the views of only one state on the matter, the United States of America, views which have had their development surrounded by prejudice and religious morals from political elites. After the establishment of the UN and the gradual consolidation of the USA as the world's hegemonic power it was possible to solidify a regime with criminal character on international level ongoing currently.
O modelo de Guerra de 4ª Geração e Guerra Híbrida na Ucrânia do começo do século XXI
Authors: Costa Simões Antunes Thiago Henrique , Santos Lima Everton
Published: March 2023

When scanning the trajectory of the “evolution” of the hegemonic ways of waging war, it appears that in contemporary times, there is an aberrant shift in relation to proportional progress with regard to the previous model. The warlike technological repertoire available, coupled with political and economic agendas, have reached levels and disastrous proportions never seen before. In this way, this article aims to clarify in an express way the association between the terms "4th Generation War" and "Hybrid War", in order to compare the disposition of the movements that animated the turbulences of the Ukrainian political-social environment, in the events of the Orange Revolution, the Euromaidan and the annexation of Crimea by Russia, understood from these two models. The research procedures adopted consist of a bibliographic review of works related to the theme, articles published in scientific journals and registered academic productions. In the outcome of the investigation, it was possible to identify the central role played by governments of other countries and international organizations conducted, above all through social media vehicles in the impetus of the revolutionary process, which, however, despite imposing significant changes in the territory, remained resigned to the rays of domination outlined by the attacking hegemonic actors.
O poder parador da água no realismo ofensivo e o advento das Armas Hipersônicas
Authors: Alberto de França Luiz
Published: March 2023

Introduced by John J. Mearsheimer in The Tragedy of Great Power Politics, the concept of the Stopping Power of Water is a fundamental principle of what he calls Offensive Realism, a theory according to which the great powers of the International System of States seek to maximize their power in order to achieve an eventual hegemony, whether it be regional or global. The Stopping Power of Water represents an obstacle to the power projection of a given country when it employs conventional military forces. However, the argument presented here is that today's hypersonic weapons, especially hypersonic gliding vehicles, represent an apparent overcoming of such a concept. At the beginning of the nuclear age, for a brief window, the United States had a nuclear monopoly, an essential condition for global hegemony according to Offensive Realism. When the Soviet Union detonated its first atomic bomb, that strategic window began to close. This article argues that, within specific conditions of nuclear conflict, the Stopping Power of Water, as proposed by Mearsheimer, loses value. Even more, the Russian Federation today finds itself in a window of strategic advantage with its new classes of war equipment, mainly the HGV Avangard. This article analyzes the historical conditions that led to the development of these weapons as well as their potentialities. It also seeks to integrate the main principles of nuclear doctrine from the Cold War with the strategic implications that the introduction of hypersonic weapons on the battlefield brings to the political-military apparatus of the great powers.