bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluation of cognitive, emotional, and social trans-diagnostic structures in severe predictions in adolescents with and without sub-clinical symptoms of emotional disorders
Authors: Javadi Vahideh , Ahmadi Farzaneh , Salek Ebrahimi Leila , Fakoor Ehsan , Dadashi Mohsen , Mousavi Elnaz
Published: November 2022

Background. The purpose of this study was to compare the meta-diagnostic constructs of emotion regulation, negative repetitive thoughts, cognitive flexibility, and social adjustment in two groups of adolescents with and without preclinical symptoms of emotional disorders. Methods. The samples of this cross-sectional and comparative research includes included 140 teenagers who were divided into two groups. Adolescents were divided into two groups based on the diagnostic interview and DASS-21 questionnaire. Statistical analysis of the data was done using the Mann-Whitney and Chi- 2 square tests. Results. Cognitive flexibility and emotion regulation in the group of healthy adolescents was significantly higher than the group of adolescents with preclinical symptoms. However, the level of social adjustment was not significantly different between the two groups of adolescents with preclinical symptoms and healthy adolescents. Conclusion. The significant difference between the two groups of teenagers in meta-diagnostic structures shows the importance of these factors in the process of prevention, diagnosis, and treatment of emotional disorders and symptoms such as anxiety and depression. Practical Implications. Considering the existence of significant differences in the two groups of adolescents in meta-diagnostic cognitive and emotional structures, effective measures can be taken in order toto prevent the complete clinical manifestation of emotional disorders; . As a result of these measures, he took an important step can be taken in to reducing reduce the financial, psychological, and social costs caused by these disorders
Alpha-Amylase Immobilization: Methods and Challenges
Authors: Mafakher Ladan , Ahmadi Yasin , Khalili Fard Javad , Yazdansetad Sajjad , Gomari Sina Rezaei , Elyasi Far Babak
Published: November 2022

Alpha-amylase is one of the most widely used enzymes in the starch industry. However, industrial application of soluble alpha-amylase is hampered by changes in pH and temperature (adverse effects on enzyme stability) and activity loss, leading to higher costs. Immobilization of alpha-amylase is an efficient strategy to reduce the enzyme losing and subsequently reduces costs in this regard. Alpha-amylases are immobilized by adsorption, entrapment, covalent attachment, and cross-linking. A barrier in alpha-amylase immobilization is the large size of its substrate, namely amylose and amylopectin. Most of these immobilization methods decrease the affinity of the enzyme for its substrate as well as the maximum rate of reaction (Vmax). This review aims to study different aspects of alpha-amylase including enzyme activity, applications, structure, starch, immobilization methods, and immobilization’s obstacles to improve alpha-amylase efficiency in the industry and also lowering the costs related to providing this enzyme.
The Influence of β-Alanine Supplementation on Recovery Biomarkers in Adults: A Systematic Review and Meta-Analysis
Authors: Mahmoudinezhad Mahsa , Zarezadeh Meysam , Pourteymour Fard Tabrizi Fatemeh , Jamilian Parsa , Jamilian Parmida , Ostadrahimi Alireza
Published: November 2022

Background: Clinical studies, investigating the effect of β-Alanine (BA) supplementation on recovery biomarkers in physically active individuals, have generated inconsistent results. This systematic review and meta-analysis study aimed to clarify the clinically relevant dietary effects of BA supplementation. Methods: A comprehensive search was done in the electronic databases of Scopus, PubMed, ISI Web of Science and Embase from inception to 2022. Meta-analysis was done using the random-effects model. Pooled effect size was evaluated using standard mean difference (SMD) and 95% confidence intervals (CI). Heterogeneity of between-study was evaluated according to Cochran’s Q test and I2 . Subgroup analysis was conducted to identify the potential sources of heterogeneity. Results: Overall, 32 studies were included in the current study. The results suggested that BA supplementation increases carnosine level significantly (SMD: 0.22mmol/L, 95%CI: -0.17, 0.61, P=0.27) but no effect was shown about lactate, fatigue, VO2 , pH and bicarbonate (HCO3 - ) (P>0.05). Subgroup analysis revealed a significant association of VO2, carnosine and fatigue with supplementation dosage, gender and duration of administration respectively. Conclusion: BA supplementation emerged its beneficial effects on enhancing carnosine level which highlights its ergogenic effects. In contrast, no significant effects had been shown in term of fatigue delay and blood levels of lactate, HCO3 - , pH, and VO2 value. These results warrant more investigation in a prospective design to clarify the exact mechanism in this way.
Bio-sorption of Methylene Blue by Defatted Seed of Adansonia digitata
Authors: Gaye Aïssatou Alioune , Diouf Ramatoulaye , Fall Alioune
Published: November 2022

The study was carried to evaluate the ability of defatted seed of Adansonia digitata (DFSE) to remove methylene blue dye from contaminated water. The optimum parameters such as contact time, particle size, absorbent dose, initial dye concentration, and pH were investigated by performing batch experiments models. The kinetics and the isotherms adsorption were evaluated by varying the initial concentration and using the optimum parameters. The optimum of contact time is 90 min and the removal capacity is 99.34 %. A mass of 700 mg is sufficient to reach the maximum removal of methylene blue (99.44 %). The maximum adsorption is obtained with an initial methylene blue concentration of 75 ppm (98.53 %). The optimum particle size is 100 mm. The kinetics of the adsorption process are in accordance with the pseudo-second order model. Experimental values of the adsorption capacity are close proximity to the optimum values predicted by the pseudo-second order model. The Langmuir, Freundlich, Dubinin-Radushkevich and Tempkin isotherms are not suitable to explain the experimental isotherm.
Studi Eksperimental Pengaruh Konfigurasi Penampang Sekat Terhadap Kinerja Novel Cooling Tower Prototype
Authors: Afandi Dedi , Syuhada Ahmad , Sary Ratna , Zulfan Zulfan , Yufandi Asra
Published: November 2022

Cooling towers are widely applied in industries such as power plants and oil refineries, where the equipment produces excess heat that needs to be removed. The effect of baffles configuration on the performance of the novel cooling tower prototype was studied experimentally. The configuration of the baffles used is the baffle section without holes, the baffle section with 15 holes, the baffle section with 25 holes, and the baffle section with 35 holes. The water inlet temperature was varied, namely 55⁰C, 75⁰C, and 90⁰C. water is flowed from the main reservoir to the upper reservoir of the cooling tower using a pump, and water from the upper reservoir falls on the baffles of the cooling tower. Inlet water temperature, outlet water temperature, and water temperature at each baffle were measured using a thermocouple. The results showed that the cooling tower with a baffle of 35 holes produced the most optimal performance. The heat transfer rate produced by the cooling tower with a 35-hole baffle at an inlet temperature of 55⁰C is 624.64 Watts. At the water inlet temperature of 75⁰C, the average heat transfer rate produced by the cooling tower with a 35-hole baffle increased by 42.6%. The average heat transfer rate produced by a cooling tower with a 35-hole baffle at a water inlet temperature of 90⁰C increased by 62.6%. This is because the cooling tower with a baffle of 35 holes causes the water droplets that pass through the baffle to split into more and more so that the heat transfer rate is higher.
Kendala Pembelajaran Online Selama Pandemi Covid-19 Di Kampung Madurasa Bojong, Purwakarta
Authors: Malia Jamil , Imam Tabroni
Published: November 2022

Penelitian ini di lakukan bertujuan untuk mengetahui permasalahan yang ada pada masyarakat khususnya para pelajar mengenai kendala pembelajaran daring di kampung Madurasa selama pandemi Covid-19. Masih banyak para pelajar yang mengalami kendala dalam pembelajaran daring, salah satunya para pelajar kurang memahami materi pelajaran yang sudah disampaikan oleh guru/dosennya. Penelitian ini menggunakan metode kualitatif dengan pendekatan studi kasus melalui wawancara dan observasi. Hasil penelitian menunjukan bahwa kendala pembelajaran daring di kampung Madurasa (1) sulit dalam mengoperasikan gadget, (2) sulit dalam pembelian paket data internet, (3) sulit dalam jaringan, (4) sulit memahami materi pelajaran yang sudah dijelaskan oleh guru/dosen
Overview of Services and Characteristics of Pregnant Mothers in the Era of the Covid-19 Pandemic in Bpm Pera Clinic in 2022
Authors: Oktaviance R. Oktaviance , Risda Mariana Manik  , Bernadetta Ambarita  , Charolina Moriana Sipakkar  , Charolina Moriana Sipakkar
Published: November 2022

Based on the centeres for Disease Control and Prevention report, pregnant women who are positive for Covid-19 are at higher risk for premature birth (delivery od babies earlier than 37 weeks) and stillbirths. In addition, pregnant women who are positive for Covid-19 are also at a higher risk of developing other pregnancy complications. The problem of psychlogical disorders often occurs during the pregnancy proces, both in the first, second and third trimesters, Covid-19 causes various clinical manifestations, especially in pregnant women, because pregnant women are a high risk group for contracting the Covid-19 virus. The sampling technique is a accidental sampling. The sample in this study are 31 pregnant women. The results show that the characteristics based on the service of the respondents almost  all experienced a fairly good change in service (90.3%), the characteristics based on the respondent’s education most of them have high school education (70.9%), the characteristics based on the respondent’s exposure are mostly working (64.5%), the characteristics are based on age most respondent’s are aged 20-29 years (45.1%), the characteristics based on parity of respondent’s are mostly multiparous parity (45.2%).

Conclusion the level of education, type of work, gestasional age, and parity of pregnant women have a very important distribution in influencing services and characteristics of pregnant women in the future pandemic Covid-19.
Mobile Web Application Development in Administration Services in Nursing Department Laboratory
Authors: Putriningtyas Ivony FN , Lourdes L Situmorang
Published: November 2022

Many skills laboratories have been depending on various progress technology information for help and make it accessible in management administration in the skill laboratory, including using computers and software/ applications. Study this use type research and development. The development model in the build system uses SDLC (System Development Life Cycle) with the Waterfall model. This study is quasi-experimental research with one group pretest and posttest designs. Applications created containing loan tools and space laboratory, reporting inventory equipment laboratory, documentation activity practicum and system evaluation and reporting. The sample in a study consists of 40 selected respondents using a purposive sampling technique. Test convenience use application uses a questionnaire consisting of 12 questions with a choice very appropriate, appropriate, sufficient appropriate, no suitable, very no appropriate. Data analysis used paired sample t-test. This mobile website is named SiMAPiN based on nine items of need: user, item, category item, unit goods, officers, submissions loan, submission item, category application and borrowing. The analysis shows a change perception of convenience in using application loan tools and goods laboratory (p-value =<0.001). The average change perception is as much as 13.1 points (33.7 – 46.8). The effectiveness of the application of the results is -5.98, which is enormous (>2.0). We conclude that application loan tools and materials, as well as room, can make it easier for stakeholders and laboratories to do management laboratory. Moment conducted testing application, got results that occur enhancement perception to convenience use application. Future research could focus on integration applications this with procurement goods Required laboratory government.
Epoxy-Red Lead Oxide and Hybrid Composites Thermal Properties
Authors:   Department of Mechanical Engineering, VTU-RRC Belagavi (Karnataka), India., Dandapani  , K Dr. Devendra ,   Department of Mechanical Engineering, SKSVMACET-Laxmeshwar (Karnataka), India.
Published: November 2022

Epoxy resins are used as Lightweight Automotive components, hydrophobic coating, corrosive-resistant thermosetting linings, and other applications. To understand the effect of epoxy resin with Graphene(G)-red Lead oxide (Pb3O4) filler with the application of heat, the thermal behavior of the hybrid composite material is studied in detail. Microstructure characterization of the produced composites had performed employing EDX and SEM. Analyses of the epoxy matrix microstructure have confirmed a relatively uniform distribution of fillers. TGA, DSC, and Longitudinal heat flow methods, were used to determine the thermal behavior of prepared materials by ASTM standards. Heat resistivity and Thermal conductivity of the material increase by adding 0.5 wt% of G initially increase but decreases with an increase in the density of the composite. Specific heat capacity and CTE increase with density for hybrid material. A decrease in Diffusivity indicates a proven thermally insulating material. A simple method adopted for fabrication tends to reduce cost. Epoxy-based Graphene-red lead oxide with modified properties has proven to be a good insulating material.
METHOD DEVELOPMENT AND VALIDATION FOR THE SIMULTANEOUS ESTIMATION OF GRAZOPREVIR AND ELBASVIR IN BULK AND PHARMACEUTICAL DOSAGE FORM BY RP-HPLC
Authors: Gayathri Kudithi , Varri Gowthami , Latha P.V. Madhavi , Devi P. Uma
Published: November 2022

A simple, Accurate and precise method was developed for the simultaneous estimation of Grazoprevir and Elbasvir Tablets. Chromatogram was
run through Std Discovery C8 250 x 4.6 mm, 5m. Mobile phase containing Buffer 0.1% OPA: Acetonitrile taken in the ratio 45:55 was pumped
through column at a ow rate of 1 ml/min. Buffer used in this method was 0.1% OPA buffer. Temperature was maintained at 30°C. Optimized
wavelength selected was 260 nm. Retention time of Elbasvir and Grazoprevir and were found to be 2.503 min and 3.004. %RSD of the Elbasvir and
Grazoprevir were and found to be 0.3 and 0.4 respectively. %Recovery was obtained as 98.17% and 99.83% for Grazoprevir and Elbasvir
respectively. Obtained LOD, LOQ values from regression equations of Grazoprevir and Elbasvir were 0.24, 0.73 and 0.06, 0.19 respectively.
Regression equation of Grazoprevir is y = 24933.x + 37206 and that of Elbasvir is y = 21941x +756.6. Results show that the retention and run time
were decreased, so its evident that the method developed was simple and economical that can be adopted in regular Quality control test in
Industries.
A PROSPECTIVE STUDY TO KNOW THE TRENDS OF SCRUB TYPHUS INFECTION DURING THE SEASONAL OUTBREAK AT A TERTIARY CARE HOSPITAL IN SOUTH RAJASTHAN, INDIA
Authors: Kulshrestha Anjali , Bohra Shweta , Jani Manoj Vasudeo , Varania Neelima
Published: November 2022

Scrub typhus is a rickettsial disease caused by the organism Orientia tsutsugamushi. The overall mortality varies from 7% to 30%, next only to
malaria among infectious diseases5. This prospective study was conducted with an aim to know the prevalence of the disease, sex ratio signicance
and impact of seasons in the disease outcome in Rajsamand, Rajasthan. A total of 515 samples were received from different clinical departments at
Ananta Institute of Medical Sciences and research center, Rajsamand from December 2020-December 2021, in which 88 samples were IgM
Antibody reactive by Rapid card test and positivity is 16.7%. Scrub typhus infection was found comparatively more in female patients i.e., 48[55%]
than in male patients 40 [45%]. The female to male ratio was 1.2:1. In the present study, majority of the patients 29 (32%) were from the age group
of 31-45 yrs and about 19 (22%) were between 16-30 yrs. Maximum cases 31(35%) had occurred in the month of September followed by 27(31%)
in October, 21(24%) in November and 4(5%), 3(3%), 2(2%) in the month of August, July and December 2021 respectively and not a single case
reported in the month of December 2020 and from January 2021 to June 2021. So, scrub typhus should always be considered in the list of
differential diagnosis of a young febrile female patient of this region mainly during the end of rainy season. This will help in proper diagnosis,
timely and adequate treatment and avoidance of complications which are associated with high mortality
“COMPARISON OF HANDS OFF & HANDS ON TRAINING IN BASIC LIFE SUPPORT: A MANNEQUIN-BASED STUDY “
Authors: Ahirwar Arun , Jaiswal Chhavi , Gupta J.K. , Maheshwari Harsh
Published: November 2022

Background Cardiopulmonary Resuscitation (CPR) is a life-saving technique that can reduce the mortality in patients with cardiopulmonary
failure by upto 3 times. Its effectiveness relies on the correct knowledge, technique and most importantly skill of the performer which has been
found to be inadequate even among healthcare professionals. This may be improved by designing better training methods that aim at enhancing the
skills of the performer. Objective This study aims to compare the hands-on training method utilising mannequin (Mannequin Group) versus
training without use of mannequin (non-mannequin group or control group) in the Basic Life Support (BLS) training. We evaluated the effect and
utility of using mannequins to follow along with BLS training. Method This prospective experimental study was done on nal year medical
students and interns. Participants were randomly assigned to either mannequin group or non-mannequin (control group). Both groups were given 3
hours long BLS training but all participants of mannequin group were given a mannequin for follow along practice during the training while the
other group was kept as control. Both groups were analysed for knowledge via MCQ based test and skills were assessed on 3-point Likert scale
immediately after the training. Results Atotal of 179 participants enrolled for the study (randomly assigned 90 in mannequin group and 89 in nonmannequin group). Post-training knowledge scores were 17.20 ± 11.17 for the mannequin group versus 16.53 ± 2.28 for the control group (p>
0.05). Post-training skill scores were signicantly higher for mannequin group in 28 of the 30 skills tested when compared to control group
(p<0.05). Conclusion Use of mannequins to follow along with BLS training is an effective tool that signicantly improves the skills of participants
but has no effect on the knowledge levels of participants. Hence, mannequins hands-on training should be made mandatory in every BLS training as
it signicantly improves the skill level of healthcare professionals which may result in the reduction of patient mortality.
Adaptability Study of Yield and Yield Related Trait Performance of Improved Bread Wheat (Triticum aestivum L.) Varieties in North Shewa Zone Oromia, Ethiopia
Authors: Negash Geleta , Birr Alemayew
Published: November 2022

Bread Wheat (Triticum aestivum L.) is an important cereal crop, which receives the most attention of specialists in plant breeding and production as worldwide. The Knowledge of the interaction between genotypes and environment with yield and yield components is a key aspect of effective selection in crop improvement. Therefore, the objective of this study was: to identify Adaptable bread wheat variety/ies with high level of grain yield and yield stability across locations. The study used 16 bread wheat released varieties, against local check at Fitche Agricultural Research Center (FiARC) in 2020-2022 cropping season. Ten important agronomic traits data were evaluated. Analysis of variance noticed significant difference, among varieties in both separated and combined analysis of variance. The combined ANOVA and the additive main effects and multiplicative interactions (AMMI) analysis for grain yield across environments exhibited significantly affected by environments, which explained 76.6% of the total variation. The genotype and genotype environmental integration were significant and accounted for 8 and 13.1%, respectively. Principal component (PCA) 1 and 2 accounted for 6.5 and 3.5% of the GEI, respectively, with a total of 10% variation. Generally, Sanete and Dandaa varieties were identified for yielding ability and stability, and recommended for the study area and similar agro-ecologies.
Disc Space Involvement in Cervical Spondylotic Myelopathy: A Prospective Study
Authors: B. Miah M. , K. Ahsan M. , Y. Ali M. , U. Zaman S.
Published: November 2022

Introduction: Cervical spondylotic myelopathy (CSM) most frequently occur in old age because of degenerative change in the cervical vertebrate, intervertebral disc, and hypertrophy of ligamentum flava that create pressure on the spinal cord. Cervical spondylotic myelopathy manifests as long-tract clinical findings in the upper and lower extremities caused by spinal cord compression. Cervical myelopathy is a clinical syndrome that may result from cervical spondylosis. When cervical myelopathy is a result of spondylosis, it is referred to as cervical spondylotic myelopathy. The study aimed to analyze the involvement of the disc space of the vertebral column in cervical spondylotic myelopathy. Methods: This study was carried out at the department of orthopaedics, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh. The study was conducted on 30 participants from March 2012 to September 2014. Result: Among the 30 cases, 24 (80%) cases were male and 6 (20%) cases were female. The age range was from 31-60 years. 15(50%) were manual workers, 12(40%) were sedentary workers and 3(10%) were housewives. the majority of the patients 15(50%) had suffered from the symptoms for 10 to 12 months. The most common level of myelopathy was the C5/6 level 13 (44.44%). Among the 30 patients, 27 (90%) cases were presented with myelopathy and the other 3(10%) cases were presented with myeloradiculopathy. Conclusion: Cervical spondylotic myelopathy is a progressive neurological disease that requires surgical intervention in most cases. In terms of interspace disc involvement, C5 C6 was the most frequent space which is 66.7%. C4 C5 and C6 C7 had the same frequency of involvement which was 10% indicating the second most common spaces concurrently.
Update on Standard Radiography in the Management of Osteo-Articular Emergencies in the “Marie Curie” Medical Clinic
Authors: Ousmane Traoré , Oncoumba Diarra , Alassane Kouma , Djoumé Diakité , Lansenou Bagayoko Ousmane , Mamadou N’Diaye , Diallo Mahamadou , Siaka Sidibé , Diaman Keita Adama
Published: November 2022

Introduction: Bone and joint emergencies mainly include traumatic lesions and bone and joint infections. The aim of the work was to report the current place of standard radiography in the management of traumatic osteo-articular lesions in the Medical Clinic "Marie Curie" of Bamako. Materials and Methods: The study took place in the radiology department of the Medical Clinic ''Marie Curie'' in Bamako, Mali. The 1745 patients who underwent standard radiography during the 12-month period were studied. The parameters concerned were the socio-epidemiological aspects and the type of simple or complex trauma. Results: In our series, the male sex was dominant in 58% of cases. Public road accidents were the most accident-prone with 78%. 61.37% of radiographs were pathological. The lower limb was the most affected (40%). The most affected joint was the knee (24%), followed by the ankle/foot (17%), the shoulder (7%) and the elbow (6%). The skull and spine were affected in the order of 4% of cases and 2% of cases. There was associated soft tissue involvement in 68% of cases. Conclusion: The permanent availability of standard radiography and modern cross-sectional imaging methods such as the scanner in commune V in the city of Bamako is becoming more than ever a necessity because the diagnostic approach to osteo-articular trauma now calls on its imaging resources for appropriate treatment.
Anorectal Buschke-Löwenstein Tumor: A Case Report
Authors: Snoussi A. , Zouaoui M. , Boubakr F. Z. , Elmoutaouakil N. , Noubail S. , Boussouab M. , Boustani S. , Hnach Y. , Azouaoui M. , Aqodad N.
Published: November 2022

Giant condyloma acuminata (GCA) or Buschke Lowenstein tumour (BLT) is a rare clinical entity of viral origin, transmitted essentially by sexual transmission, and is common in immunocompromised patients. It develops in the genital or perianal area, creating a large, bulging lesion that may be ulcerated or fistulised in neighbouring organs. The search for other associated sexually transmitted infections is mandatory. A rigorous clinical examination and additional imaging allow a precise assessment of the lesion to be made. Treatment is essentially surgical and must be extensive because of the tumour's high recurrencepotential. Neo-adjuvant treatments such as chemotherapy or immunotherapy deserve to be better evaluated to limit the disabling nature of surgery.
Safety and Quality Assessment of Milk Before and After Pasteurization Collected from Different Regions of Punjab
Authors: Rimsha Rimsha , Munir Javeria , Fatima Ishrat , Ishfaq Naba , Shahid Haiqa , Murtaza Haneeza , Haroon Khursheed
Published: November 2022

Milk is an excellent source of proteins, fats and carbohydrates along with minerals and vitamins. It is the balanced diet for all age groups. In Pakistan consumption of milk is increasing day by day. Milk from different animal sources has quality and nutritional differences. Pasteurization found to be increased the milk quality and shelf-life stability by reducing microbial load. The objective of study is to evaluate the differences among the raw and pasteurized milk in terms of safety and microbial distribution. The proximate and quality analysis including moisture, crude protein, crude fat, total soluble solid, pH, acidity, lactose composition, solid-not-fat (SNF) and specific gravity were done for the milk samples. The microbial tests were performed for Total Plate Count and Total Coliform Count before and after pasteurization process. The collected data was analysed statistically to estimate the level of significance. Pasteurized milk of buffalo showed high value for pH 6.65, lactose composition 5.964, crude fat 7.974%, crude protein 6.453%, SNF 6.672%, Total solids 12.646% while pasteurized cow milk showed low value as compare to buffalo milk samples as pH 6.60, lactose composition 4.732, crude fat 4.744%, crude protein 4.353%, SNF 6.128%, Total solids 10.872%. Total Coliform count (TCC) for raw and pasteurized milk of cow was 3.320 CFU/ml and 1.2600 CFU/ml respectively, whereas for buffaloes it was 2.604 CFU/ml and 1.0900 CFU/ml respectively. In case of TPC it was 2.834CFU/ml and 1.132 CFU/ml for raw to pasteurized milk of cow while it was 2.0320 CFU/ml and 1.0720 CFU/ml in buffaloes. Result revealed that pasteurized milk is safer to use and pasteurized milk has low microbial count as well as authenticity in safety and quality when compared with unpasteurized milk.
Effect of Environmental Factors on Bunker Temperature and Pressure; A Study from Region with Harsh Tropical Weather
Authors: Ibrahim Hassan , Bello Usman
Published: November 2022

Background: Stabilization of weather factors especially temperature, pressure and humidity in bunkers that housed the Linear accelerators is necessary for safety of equipment and their efficient function for our patients. Daily variation of such factors can lessen the performance of Linear accelerators resulting to an error in their output and wrong dosimetry. Sokoto centre being located in the North-Western region of Nigeria with three unique seasons (Dry hot, Harmattan winter and Wet raining seasons) require a study of this kind to ascertain the influence of those harsh environmental factors on bunker's internal air condition. Methods: Daily records of Linac bunker temperature and pressure were measured using Precision mercury-in-glass thermometer and Opus barometer (OPUS 10 THI) from January 2019 to December 2021. Similarly, the corresponding daily external environmental temperature and pressure for the study period were obtained from Nigerian Meteorological Agency. The values were grouped according to the months of year, mean values of temperature and pressure for each month of the year were generated and graphs and bar-charts were plotted for both bunker and external environment. Similarly, an overall mean score for both temperature and pressure of each month of the three years period were generated and graphs were plotted with those values for bunker and external environment. Results: The overall mean external temperature for the study period was 35.7°C, ± 3.82 as standard deviation (SD) and with a range of 26.0 – 43.6 °C, while for the overall mean bunker temperature it was 27.1°C ±1.7 SD and a range of 23.1 - 31°C. For the external environmental pressure, the overall mean value was 78.1hpa ± 1.5 as SD and a range of 68.1– 83.1hpa, while for the bunker it was 977.2 hpa ± 2.55 as SD and a range of 966.9 – 988.7 hpa. Using the pearsons correlation, it indicate that there is a significant association between environmental and bunker temperature (p-value=0.002). Conclusion: External environmental temperature showed a significant influence on bunker temperature despite the presence of chillers. But for environmental and bunker pressure, the relationship is complex and non-significant. Similarly, the seasons of the year also influenced bunker temperature.
Abnormal Haematological Indices in Cirrhosis in a Tertiary Care Hospital
Authors: Rahman Dr. Mohammad Mizanur , Hossain Dr. Md. Liakat , Ali Dr. Md. Haidar , Ullah Dr. A. Z. M Ahsan , Hasan Dr. Md. Rashedul , Amit Dr. Muhammad Nafees Hussain , Talukder Dr. Kshitish Chandra
Published: November 2022

Background: The haematological changes are common in cirrhosis of liver the cause of which is multifactorial. It should be correlated by determining the underlying pathology accordingly. Objective: The objective of the study was to evaluate the pattern of change in Haematological indices in Cirrhosis of liver. Methods: This is a cross sectional prospective study conducted on purposely selected (non-probability) hospitalized patients admitted to Medicine, Gastroenterology and hepatology departments of Dhaka Medical College Hospital, Dhaka, Bangladesh. A total of 100 cases of cirrhosis were selected as per inclusion and exclusion criteria. After selection clinical history, meticulous physical examination and rational investigations were done. Data were collected as per a structured standard questionnaire and checklist. Data analysis was done using statistical software package SPSS 22.0 and was compared with other studies. Results: Anaemia was found in 81 cases out of 100 patients. Anaemia was morphologically normocytic in 46% patients which is the highest number in this study group. It was microcytic in 40% patients and macrocytic in 14%. Regarding Leukocyte count it was normal in 70(70%) patients, Leukopenia in 12(12%) and Leukocytosis in 18(18%) patients. Regarding platelet count it was normal in 46(46%), thrombocytopenia in 51(51%) but thrombocytosis in 3(3%) of cases. The average platelet count in thrombocytopenic patients was 90 X 1091 ± 23 X 109/L. Lastly, pancytopenia was present in 14(14%) patients. Among them, 10 patients (71%) had splenomegaly. Iron Profile was done in all patients of microcytic anaemia and it revealed 68% of them were iron deficiency anaemia. Prothrombin time was done in all patients and it was prolonged in 54 (54%) and its average value was 16.13±.2.9 seconds. Conclusion: Haematological changes are common in cirrhosis of liver, the cause of which is multifactorial. Iron deficiency anaemia is the common type (68%).Prolong prothrombin time (54%) and thrombocytopenia (51%) are the common features.
Formulation and Evaluation of Self-Micro Emulsifying Drug Delivery System (SMEDDS) of Ticagrelor
Authors: Vadapalli Ratna Sree , M Sunitha Reddy,
Published: November 2022

The present work mainly emphasized on the enhancement of solubility of Ticagrelor by developing Self- Micro emulsifying drug delivery system. Ticagrelor is a BCS class IV drug with poor aqueous solubility and permeability. The saturated solubility of Ticagrelor in various oils, surfactants and co-surfactants was determined by using UV-spectroscopy. The excipients were selected based on their maximum solubility and compatibility for Ticagrelor. SMEDDS formulations od Ticagrelor were developed using different oils, surfactants and co-surfactant combinations (4:1 and 3:1). Pseudo ternary phase diagrams were constructed and based on pseudo ternary phase diagrams, Nano emulsification area was evaluated .Formulations were designed based on the pseudo ternary phase diagram using various proportions of oil (Capmul MCM E8 EP), surfactant (Labrasol), co-surfactant (PEG-400). The prepared formulations were selected among them F1 was optimized and carried out for further evaluations like dispersibility test, self-emulsification time ,phase separation and stability test, thermodynamic stability studies, droplet size and zeta potential, invitro drug release studies. The results of present study demonstrate that Ticagrelor SMEDDS can be used as a potential means for improving the solubility of Ticagrelor.
Driver Stress Detection Based on IOT Motion Sensor Using Wearable Glove
Authors: S.M Revathi , R Srinivasan , C.R Balamurugan , H Kareemullah
Published: November 2022

Stress conditions experienced by the driver is a serious problem in road safety. Driver error is the most common cause of road accidents. In this paper skin conductance is taken for analysis of driver drowsiness fatigue and mental stress. In order to minimize human error while driving it monitors stress and fatigue by measuring physiological parameters like skin acting like a conductor gives a response also called as Galvanic skin response and the motion is continuously monitored over a period of time. Internet of Things (IOT) based sensor used in driver’s health care is novel approach from the classical ways that includes visiting hospitals for clinical procedure and constant supervision of the person. It connects the health care professionals with the driver through smart device to monitor vitals without affecting the freedom of movement of the driver. This chapter introduces a viewof IOT functionality and its application with the sensing and wireless technique for implementing the required stress monitoring system for drivers. Further the Captured data is sent to an IOT Cloud Where Machine learning algorithms were deployed for computing the percentage of alertness and stress if the stress levels go beyond the threshold levels, then alert signal is sent to the driver from buzzer.
Artificial Intelligence in Healthcare Analytics
Authors: Kumar Krishna Priya , Baskaran Padmashree , Thulasisingh Anitha
Published: November 2022

The evolution of lifestyle had eventually turned down the hale and health statement of humans. This led to the gradual upsurge of various diseases in humans irrespective of their age. On the other hand, innumerous healthcare data generated from the wide range of medical sectors challenged the human brains. To combat those human setbacks in data handling there arose the revolutionary solution through machines using mathematical algorithm entitled as Artificial Intelligence (AI). The employment of Artificial Intelligence is traced in medicine pipeline commencing from diagnosis of disease until treatment. AI registered its pivotal role in clinical section by processing (diagnosis, image processing, drug discovery, digital pathology, oncology, mutation identifications) such huge data using algorithm. One of the major subset of AI is Machine Learning (ML), which competes with the humans cognitive skills using higher order algorithms comprising of Artificial Neural Network (ANN). The complicated nature behind the diseases like cancer, diabetes, cardiology, neurological and psychological disorders can also be unveiled with the assist of AI. The processing of healthcare related database executed by AI provides data with high accuracy and clarity. Overall, human intelligence assess their vast health database requirements using the Artificial Intelligence.
Peranan Jaksa Pengacara Negara Dalam Penyelesaian Sengketa Perdata Nomor 10/Pdt.G/2017/Pn.Slk
Authors: Arianto Eri , Andri Andri
Published: November 2022

The duties and authorities of the prosecutor in the criminal field are regulated in Article 30 paragraph 1 of the Prosecutor's Law. Then the prosecutor's authority in the civil sector is regulated in Article 30 paragraph 2 of the Prosecutor's Law which is a civil relationship between members of the public which is usually based on an agreement, the prosecutor can play a role in civil cases if the State or government becomes one of the parties and the prosecutor is given the power to representing the state, hereinafter referred to as the state attorney. UUPA regulates land registration which aims to provide legal certainty. Provisions regarding the obligation for the government to carry out land registration throughout the territory of the Republic of Indonesia are regulated in Article 19 of the LoGA. To implement the provisions of the LoGA, the Government has issued Government Regulation Number 24 of 1997 concerning Land Registration. Problems regarding land registration often occur on ulayat land due to the absence of legal certainty over the ulayat land. One of the customary land disputes regarding ownership of land occurred in the Koto Panjang of Solok City, namely between the mamak head of the inheritance of the people and the local government of Solok City, namely regarding the land used as the office of the village head of Koto Long, said the head of the inheritance in her lawsuit against the local government of Solok City that the land belongs to her people but has only been certified by the local government with a usufructuary certificate. The local government of Solok City also explained that the land belongs to the Solok City government because the certificate of use rights owned by the government has been running for approximately 17 years. Solok for handling legal problems in the civil sector carried out by the State Attorney.
Inflation in the Time of Corona and War: The plight of the developing economies
Authors:   Delft University of Technology., Storm Servaas
Published: November 2022

Reliance on established macroeconomic thinking is not of much use in trying to understand what to do in response to the constellation of forces driving up inflation and slowing down growth in these times of COVID-19 and war. This paper attempts to reduce the heat and turn up the light in the debate on the return of high inflation and looming stagflation—by providing evidence-based answers to key (policy) questions concerning the return of high inflation: How close are the parallels between the current conjuncture and the 1970s? What are the differences? Does what is currently happening already amount to stagflation? Can central bankers engineer a ‘soft landing’ of their economies or are we already poised for a deep (global) recession? What are the likely spillover effects of monetary tightening in the US on the emerging economies? What, if anything, can we learn from the monetary and fiscal policy experiences and policy mistakes of the 1970s? And, finally, are there alternative, less socially costly, ways to bring inflation down?
Романтизм в польской и грузинской литературе. К вопросу сходства и отличия
Authors: Occheli Vera
Published: November 2022

The paper addresses the issue of similarities and differences in Polish and Georgian Romanticism. The analysis shows that Romanticism in Georgian literature, in contrast to Polish Romanticism, which developed in stark opposition to classicism and sentimentalism, was developed as a result of a quick and smooth process.At the early stage of Polish Romanticism, the leading genre of this literary trend was the ballad, whereas in Georgian Romanticism, it was the elegy. In Polish and Georgian Romanticism, an important genre is also the poetic novel, which is due to the socio-historical situation of Poland and Georgia: the loss of independence.
Yoga as Serious Leisure Activity: Socio-Demographic Differences in Mindfulness Levels Among Yoga Retreat Participants
Authors: Zafeiroudi Aglaia , Yfantidou Georgia , Kouthouris Charilaos , Zanna Aikaterini
Published: November 2022

Yoga retreats are an emerging component of international well-being tourism. This form of tourism focuses on groups with specific demographic characteristics and interests, highlights natural destinations of high tourism value, and supports the development of personal well-being through such practices as mindfulness. This study investigated the demographic characteristics of 203 Greek yoga retreat tourists in relation to their mindfulness levels. The study also investigated the effect of different yoga practices in asana, meditation, and philosophy courses on the formation of mindfulness. The 'Mindful Attention Awareness' scale (Mantzios, Wilson & Giannou, 2015), consisting of 15 items, was used to evaluate mindfulness and psychographics were successfully tested. The results show statistically significant differences in mindfulness between subgroups of participants of different marital status, financial profile, age, and number of years practicing yoga meditation and philosophy. The study concludes that yoga is a serious leisure activity with high personal and work life involvement. The findings enrich data regarding yoga retreats in Greece and establish the profile of yoga retreat participants according to mindfulness, asana, meditation, and philosophical practice participation. Tourism providers can give prominence to the concept of mindfulness as a dominant theme in the wellness tourism industry and, as a consequence, develop and improve the quality of yoga retreat services.

 

Received: 30 August 2022 / Accepted: 13 October 2022 / Published: 5 November 2022
Articulation Strategy for the Strengthening of the Management of Social Entrepreneurship Projects, South Region of Colombia Experience
Authors: Rincón-Guio Cristian , Quintero Jennifer Tovar , Losada Juan Carlos Salazar , Rincón Zaida Yonerica Cacua , Escobar-Molina David Felipe , Deño-Ramírez Juan Diego Ce , Torres Jose Eduardo Corredor
Published: November 2022

Social entrepreneurship has an increasingly important role in the solution of current social challenges. The aim of this document is to establish an articulation strategy to strengthen the management of social entrepreneurship projects in a region of southern Colombia. A mixed study was carried out by collecting and analyzing qualitative and quantitative data. Actors of the social entrepreneurship ecosystem was studied. Surveys were applied to social entrepreneurs, interviews and focus groups with experts in entrepreneurship from the academic, public and private sectors were carried out. The level of development of the social entrepreneurship ecosystem was identified through the collection of primary sources. Finally, strategies were designed to strengthen the projects of this ecosystem. The strategies focused on the ecosystem community, an enabling environment, the interconnection of the Ecosystem, Entrepreneurial Development Programs, Education, and a city-wide entrepreneurial strategy.

 

Received: 21 August 2022 / Accepted: 11 October 2022 / Published: 5 November 2022
Judicial Control Over Negative Administrative Decisions in the Saudi Legal System
Authors: Alanzi Awad Ali
Published: November 2022

In this study, we discuss the negative decision concept as the legal characterization approved by the Law for Administration's abstention or refusal to issue a decision, which is obligated to give in accordance with the laws and regulations. The study aims to determine the possibility of challenging its negative position and re-coursing if the Administrative Authority fails to perform its duty or Circumvent Law in a manner that prejudices individuals’ interests. We have clarified that every silence or abstention from Administration is not a negative decision. Rather, it is required that the Authority of Administration should be restricted upon its silence or refrain from doing as per legal requirements. Further, the negative administrative decision is a legal characterization that is not embodied in a material form, and its issuance is not subject to formal and statutory rules established for issuing explicit decisions. Therefore, it does not need to be announced to be effective in facing individuals. It is also characterized by several characteristics that distinguish it from other decisions. For example, a negative decision of the Administration may be appealed by an annulment suit after the grievance to the Administrative Authority and fulfilling the annulment lawsuit conditions. In addition, compensation for a negative decision could be obtained through a compensation claim if the damage results from Administration's failure to perform its legal duty.

 

Received: 8 August 2022 / Accepted: 12 October 2022 / Published: 5 November 2022
The Impact of Technology on Audiovisual Production in the Social Media Space
Authors: Jeljeli Riadh , Farhi Faycal , Hamdi Mohamed Elfateh  , Saidani Salami
Published: November 2022

This research is aimed at investigating the impact of technology on the production of audiovisual content within social media space. The researcher adopted a quantitative approach for investigating the relationship between the variables and a sample of 100 respondents was selected for the research. The literature review of the research found that the majority of the previous researchers have focused on the evolution of audiovisual media over the course of history while a major portion of the literature explores the social functions of social media. The researcher used a survey questionnaire for conducting the current research. The findings of the current research found that there is a significant impact of technology on the production of audiovisual content on social media space. Furthermore, the research findings also show that the social functions of social media play a pivotal role on the technological impact of audiovisual production within the social media space.

 

Received: 9 June 2022 / Accepted: 31 August 2022 / Published: 5 November 2022