bluuebunny/crossref_metadata_2025 huggingface dataset:
Middle-term cochlear implant use in case of asymmetric hearing loss and single-sided deafness: A retrospective single-centre cohort study
Authors: Louvel Rémy , Mosnier Isabelle , Lahlou Ghizlene , Nguyen Yann , Ferrary Evelyne , Torres Renato
Published: August 2022

Key points: (no abstract required) • Cochlear implant effectiveness in
asymmetric hearing loss and single-sided deafness is well established,
but rarely covered by health care systems. • Continuation of wearing the
implant beyond the first year could be considered as an indirect
indicator of subjective benefit. • Percentage of cochlear implant
abandon at 5-years post-implantation was very low in patients with
asymmetric hearing loss and single-sided deafness. • High education
level, low audibility and good unaided speech perceptions scores of the
contralateral acoustic-hearing ear were positive prognostic factors of
CI use. • The low percentage of non-users is an additional strong
argument to recommend cochlear implantation in patients with asymmetric
hearing loss and single-sided deafness, on the ear with a profound
hearing loss, especially in case of frail contralateral acoustic-hearing
ear.
Study on heat and moisture exchange characteristics of counter-flow wet seawater shower cooling tower
Authors: Zhu He-gang , Qi Xiao-ni , Qu Xiao-hang , Hou Xiao-chen , guo qianjin , Yu Yang
Published: August 2022

Cooling tower is an important part of circulating cooling water system.
This paper studies the counter-flow wet seawater shower cooling tower,
establishes and verifies the detailed thermal performance calculation
model. The influences of salinity, inlet velocity and droplet diameter
on cooling efficiency, heat dissipation, gas-phase thermal efficiency
and exergy efficiency were analyzed. The results showed that the cooling
efficiency, exergy efficiency, gas-phase thermal efficiency and heat
dissipation of the upper jet column were 15.59%, 4.89%, 8.62% and
34.58% higher than those of the lower jet column, respectively. With
the increase of droplet diameter, decreased by 38.76%, Q
decreased by 78.11%, decreased by 26.30% and decreased by 33.53%
under standard salinity conditions. Under high salinity conditions, is
reduced by 35.1%, is reduced by 17.16% and is reduced by 30.55%.With
the increase of air velocity, increased by 13.76%, Q increased
by 22.44%, decreased by 6.66%and decreased by less than 2% under the
standard salt condition.Under high salinity conditions, compared with
the standard salinity, the average reduction of is 2.96%, the average
reduction of is 1.63% and the average reduction of is 2.73%. Through
the optimization analysis of seawater cooling tower, it is obvious that
selecting the best operating conditions can improve the heat and
moisture exchange characteristics of seawater cooling tower.
Review of child abuse through 20-year autopsies in Jeju
Authors: Kim Su Wan , Kang Hyun Wook , Kim Hyeok
Published: August 2022

Child abuse is defined as any type of maltreatment and neglect by an adult, which is violent or threatening for a child, including physical violence directed to the child. Children could be abused not only by a parent or caregiver, but also by other adults on whom they are dependent, such as day nursery workers, teachers, and sports coaches. While doctors are the most responsible people for reporting any type of child abuse, their care and awareness seem to be very poor and weak. We reviewed 30 autopsy cases of child abuse, in particular during the past 20 years in Jeju Island. We expect that doctors will report any child abuse more actively after reading this review article.
Clinical outcomes and characteristics of acute myocardial infarction patients with developing fever after percutaneous coronary intervention
Authors: Lee Jae-Geun , Ko Yeekyoung , Choi Joon Hyouk , Yoo Jeong Rae , Kim Misun , Boo Ki Yung , Beom Jong Wook , Kim Song-Yi , Joo Seung-Jae
Published: August 2022

The incidence of fever complicating percutaneous coronary intervention (PCI) is rare. However, little is known regarding the cause of fever after PCI. Therefore, this study aimed to determine the clinical characteristics of patients with acute myocardial infarction (AMI), with or without fever, after PCI. We enrolled a total of 926 AMI patients who underwent PCI. Body temperature (BT) was measured every 4 hours or 8 hours for 5 days after PCI. Patients were divided into two groups according to BT as follows: BT<37.7°C (no-fever group) and BT ≥37.7°C (fever group). The 2 years clinical outcomes were compared subsequently. Fever after PCI was associated with higher incidence of major adverse cardiac events (MACE) (hazard ratio [HR], 1.56; 95% confidence interval [CI], 1.07-2.28; P=0.021), all-cause death (HR, 2.32; 95% CI, 1.18-4.45; P=0.014), cardiac death (CD) (HR, 2.57; 95% CI, 1.02-6.76; P=0.049), and any revascularization (HR, 1.69; 95% CI, 1.02-2.81; P=0.044) than without fever. In women, prior chronic kidney disease, lower left ventricular (LV) ejection fraction, higher LV wall motion score index, white blood cell count, peak creatine kinase-myocardial band level, and longer PCI duration were associated with fever after PCI. Procedures such as an intra-aortic balloon pump, extracorporeal membrane oxygenation, continuous renal replacement therapy, central and arterial line insertion, and cardiopulmonary resuscitation were related to fever after PCI. Fever after PCI in patients with AMI was associated with a higher incidence of MACE, all-cause death, CD, and any revascularization at the 2 years mark than in those without fever.
Ultrasound-assisted subarachnoid block in a patient with severe kyphosis
Authors: Park Sun Kyung , Choi Yun Suk , Kim Hyun Jung
Published: August 2022

Here, we report a case of ultrasound-assisted subarachnoid block in a patient with severe kyphosis. A 69-year-old man was scheduled for metal removal from hip screws. He had a previous experience with subarachnoid block using the landmark-guided technique, but it was very difficult due to severe kyphosis. However, we could easily determine the correct needle insertion point using ultrasound imaging and performed a successful dural puncture on the first attempt. This case demonstrates the clinical usefulness of ultrasound imaging for subarachnoid blocks in patients with severe kyphosis.
Corrigendum: Biomarkers of Skin Graft Healing in Venous Leg Ulcers
Authors: Kirketerp-Møller Klaus , Doerfler Petra , Schoefmann Nicole , Wolff-Winiski Barbara , Niazi Omid , Pless Vibeke , Karlsmark Tonny , Ågren Magnus S.
Published: August 2022

Abstract is missing (Corrigendum)
THE ROLE OF EDUCATION IN INTERNATIONAL INFORMATION-SHARING SYSTEMS
Authors: Abdullayeva Shahnaz
Published: August 2022

Social life has been in constant change throughout history. Economic, political, technological and cultural advances have affected all societies at different times. Journalism, too, is a profession that emerged in this change and was renewed within the framework of these changes, and it has a very important role in terms of democratization of society. Over time, factors such as the formation of the capitalist economy, the importance of public opinion and the press, the emergence of the press as a sector and its rapid growth, together with the practical education concern for the field, created the necessary social framework for the emergence of communication science and the establishment of journalism schools. Until today, the number of journalism schools in the world and in Azerbaijan has increased continuously in line with the development of the industry. This increase shows the high demand for journalism education. First, journalism is a social phenomenon and because of this feature, it is not static but in constant change. Society and journalism have developed in mutual relations. The newspaper and the journalist itself are a product of the process of social change and journalism practices are shaped within the framework of social change.
ORGANIZATION PRINCIPLES OF TOURIST ACTIVITIES IN EDUCATION INSTITUTIONS: ACTIVE APPROACH
Authors: Aleksіeіenko-Lemovska Lyudmila
Published: August 2022

The article identifies the specifics of the organization of tourist activities in the education institutions. Forms and types of tourist activity and groups of conditions that ensure the organization of the educational process in education institutions: environmental, psychological and pedagogical, organizational are mentioned in the article. The educational process is presented as a controlled dynamic system consisting of interconnected elements that provide purposeful, step-by-step and planned activities to organize educational interaction with participants in the educational process. The article analyzes the content the activity component of the in an of organization the tourist activities in an education institutions and noted that the activity approach provides the opportunity to develop holistic integration models as well as to identify basic functions, elements, components, their relationships and interconnections, system-forming factors and the functioning conditions in static and dynamic aspects. All of organization the tourist activities in an education institutions structural components are aimed at the practical activity, in particular, the capacity of tourism specialists for solving specific pedagogical situations. The activity approach is the basis of tourist activities and should ensure the formation of readiness of tourism specialists for modeling and construction of social environment for personal development in the education system, active cognitive activity.
SYNONYMY IN MEDICAL TERMINOLOGY: THE EVOLUTION OF THE TERM «LEPRA»
Authors: Bieliaieva Olena , Lysanets Yuliia , Havrylieva Ksenia
Published: August 2022

The article considers the theoretical aspects of synonymy in terminology and analyzes the Latin synonymous terms of leprosy in diachrony. It has been shown that in the conditions of the cognitive paradigm the views of scientists on such a phenomenon as terminological synonymy, which is a lexical reality and from which terminological practice cannot be abstracted, have changed. In the course of the research, the authors applied the methods of analysis, semantic-component in particular, sampling, classification, generalization, and historical approach. The material of the study is the corpus of synonymous terms for leprosy, listed in the IV volume of the thorough work Cyclopaedia of Practical Medicine, published in 1835 in London, as well as synonyms of the term «lepra», presented in the dictionary by D. Arnaudov. The authors conclude that the presence of a significant number of synonyms of the term under study, which were common in medical discourse as of the 19th century, demonstrates that medical terminology is an open system, some elements of which are integrated by this framework and others disappear. It is emphasized that the etiology and pathogenesis of leprosy were unknown almost until the last quarter of the nineteenth century, so the vast majority of names contained a toponymic component, which indicated the endemic nature of the disease, or metaphorical, zoomorphic, in particular. The processes of terminological evolution have led to the disappearance and archaization of these terms, most of which are currently incorrect, although they provide interesting historical information for a wide range of scientists – clinicians, specialists in the history of medicine, and terminologists. With the development of medical science and terminology, there was a specialization of most terms, therefore, now they denote other medical concepts.
THE TOOLKIT OF ORAL HISTORY IN THE FORMATION OF A MASS OF ORAL HISTORY SOURCES FOR THE HOLODOMOR IN UKRAINE IN 1932–1933
Authors: Boriak Tetiana
Published: August 2022

The aim of the paper is to apply theoretical framework elaborated in oral history for the research of the Holodomor. The first aspect is relation of the collective and the individual. Regarding the Holodomor, one can find absence of pressure of official historical memory over the individual; massive of Holodomor oral history is huge (thousands of units of narrative) that allows to solve the problem of verification and to generalize the experience of the respondents in many parameters. The author also shows how problems of the degree of censoring, reference points and regarding the harmonization of the public and the private can be solves with the oral history of the Holodomor. Specificity of gender’s recalling of the past is also proposed. The second component of analyzed framework is correlation between memory and time. The author illustrates that there are no obstacles to non-trusting of the narrative of the Holodomor survivors. Third component of the framework is trauma. Using oral history, the author illustrates how witnesses to the famine express signals of the traumatic event. The article also points at such important aspect of dealing with investigating the trauma, as absence of words to express surviving through the famine. The historical method, analysis and synthesis, and also the comparative-historical method were used.
MEDIA GENRE THEORY IN LINGUODIDACTICS OF UNIVERSITY EDUCATION
Authors: Dergach Dmytro
Published: August 2022

The article examines the nature of media genreology as a modern scientific direction and educational discipline in institutions of higher education. The principles of linguistic didactics regarding language teaching and communicative dominant genres of modern mass media in the student audience are being updated. The curriculum of the course “Media Genreology” for students of higher education specializing in “Media Linguistics” at Kyiv National Taras Shevchenko University is detailed. Forms of individual and group work of students in acquiring and practicing the skills of analysis, creation and editing of mass media genres in seminar classes are modeled (face-to-face and with the use of distance learning tools). Research attention is paid to the actual implementation of the functional and stylistic method of social communication analysis in the linguistic didactics of classical university education, particularly in the field of media. In turn, the author's most optimal methods of linguistic solution of professional problems of the evolution of the genre system of media communication, which are learned by students in various forms of classroom work or remotely, are offered. Prospects for the development of media genreology as a dynamic component of the educational episteme in syncretic interaction with other medialinguistic disciplines taught in modern universities oriented to the social demand for high-quality, promising, competitive education are determined.
DIASPORA CULTURE: THE MAIN METHODOLOGICAL AND TERMINOLOGICAL ASPECTS OF CULTURE LOGICAL COMPREHENSION
Authors: Haiuk Iryna
Published: August 2022

The purpose of this article is to justify the necessary of the complex approach to study of the diasporian culture. It is shows that the culture of diaspora usually don`t considered as the original autonomous phenomenon, but only as a small separate marginal part of the native culture. This point of view bases on the outdated ansystem inefficient paradigm of so-called "Island" anthropology. One of the most effective approaches to understanding the essence of culture is theory of dissipative systems. The fact that the theory of dissipative systems not only explains but also proves the naturalness and regularity of the appearance of various branches/ directions of any culture is one of its most important results. Study of the diaspora culture that has been existed during the centuries in another country, it should include research on the entire material sphere of its life, all the artifacts created by its representatives. It is proves the expedience to use iconological method, the approaches of the Actor-Network theory (ANT) and the “Philosophy from below” in this contex. The ANT considers artifacts as active units/ actors of social relations, which make up “sociality”, as well as the principles of "Philosophy from below".
HUMOR IN THE MUSICAL-DIDACTIC WORKS OF THE BAROQUE PERIOD
Authors: Kliuchynska Nataliia
Published: August 2022

Interest in musical treatises of past epochs is part of the interpretive process of performing early music according to the methodology of historically informed performance. We find in them information about performance practice and music theory of a certain historical time. The presentation of language in treatises also triggers our interest, especially in view of a comprehensive perception of aesthetics and worldview of artists of the baroque time. A feature of the baroque art is its division into high and low styles (high and low baroque). The expressive means of the lower baroque works contain elements of humour, irony and hyperbole. However, the same means can be seen in the works of high style. The object of coverage in the paper is a conscious use of elements of lower style by artists, in particular, the emphasis on the role of humour in musical-didactic treatises of the baroque period. This combination reflects the polarity and contrast of the baroque aesthetics. A take on music theory and performance practice through the prism of laughter and irony will help to identify another spectre of expressive means in the serious genres of baroque music and embody it in interpretation.
TRANSFORMATION OF MORAL VALUES IN MODERN INFORMATION SPACE
Authors: Lopuha Oresta
Published: August 2022

It is indicated that morality in the traditional national spiritual culture has always had priority in constructing an ontological image of the world. Morality is quite difficult to shape in the conditions of mass culture because it declares the identity of material and spiritual values that act as products of mass consumption. It is pointed out that traditional values have ceased to be traditional because they are unable to meet the contemporary spiritual needs of people. The content and essence of moral norms change with changes in the social life of society. The most important crisis moments in the life of contemporary youth are analyzed. In the 21st century, such manifestations as intolerance, conflict, aggression, terrorism, and war became a particular threat to the moral values of young people. Now morality becomes global as global problems take precedence over regional problems. These are problems like the survival of mankind. Such problems bring with them the need to create a new vision of the world, to create a new moral paradigm that will significantly reevaluate traditional moral values. Such a system should be based on the common interest of human with all their conflicts and contradictions. One of the aspects of shaping the spiritual culture of youth, both innovative and consistent with high moral values, should be considered the conceptual approach within the so-called “culture of peace” that should be pursued not only as the goal of certain shaping influences, but as a strategic resource.
ALBANIAN HISTORICAL AND ARCHITECTURAL MONUMENTS ILLEGALLY RESTORED AND FALSIFIED DURING THE OCCUPATION OF NAGORNO-KARABAKH
Authors: Vusala Mammadzade
Published: August 2022

The material and cultural monuments of Nagorno-Karabakh, which were condemned to destruction by the Armenians, are our irreplaceable national wealth as a stone memory of our history. These monuments are not only material and cultural, but also “archive” pages of our spiritual history. The destruction of historical monuments of Nagorno-Karabakh was faced with the threat of erasing the fossilized memory of our history of culture and morality. The article states that the Azerbaijani state not only carries out the restoration of churches and other historical and architectural monuments in the territory of Azerbaijan but also takes an active part in the restoration and conservation of historical monuments included to many World Cultural Heritage outside the country. The peoples of different faiths and their temples living in its territory of Azerbaijan as a tolerant country are evident with undeniable facts. The “Armenian church” can be seen in the center of Baku city, in which the state of Azerbaijan shows the care it shows to other religious monuments. As Azerbaijan is a multi-ethnic and tolerant country, just as aborigines respect the religious monuments, places of faith and cultural values of minority peoples, the same feeling of respect for the national-cultural values of the aborigines, that is, Azerbaijanis, should also be promoted. Thus, as the sense of respect for one's culture among peoples and nations increases, it will also increase the respect and esteem of one's another.
INTERNET COMMUNICATION IN MODERN INFORMATION SOCIETY
Authors: Petrovich Valentina , Charikova Iryna
Published: August 2022

Basing on the examination of sufficient amount of scientific literature, the article attempts to define the concept and highlight the characteristics of the information society. It is proved that the information society is a qualitatively new historical stage of civilizational development. It is argued that the information society is based on the global spread of information and communication technologies, the fundamental processes of mass generation, processing, transmission, and use of information. It is established that the information environment contributes to a significant increase in the impact of information and knowledge on all areas of human activity. The substantiation of the paradigm of communication in the information society and its implementation with the help of the newest information technologies of the Internet is given. The peculiarities of the functioning of Internet communication in the information society are studied. It is substantiated that such communication has specific features, provides some training, establishes unique implementation forms, and actualizes the dialogic nature of a society.
DEVELOPMENT OF JEWISH STATE THEATERS IN UKRAINE IN THE 1920S AND 1930S OF THE 20TH CENTURY
Authors: Vasylenko Kateryna
Published: August 2022

The article explores the history of state Jewish theaters in Ukraine in the period 20-30s of the twentieth century. Important, previously unknown facts of organizational and creative processes of Kharkiv, Kyiv, and Odesa GOSETs are highlighted. This article describes the stages of the Soviet policy of indigenization and its influence on the development of Jewish theaters in Ukraine. The publication clearly describes the ways of each of the state Jewish theaters of Soviet Ukraine from their creation to the beginning of the Second World War, when all Jewish theaters were evacuated from Ukraine. Based on the analysis repertoire and changes in the administrative and creative management of theaters, the influence of the Soviet totalitarian regime on the theatrical art of one of the largest national minorities in Ukraine is highlighted. The first reference is made to archival documents that regulated the repertoire of Jewish theaters at the state level. The article examines the influence of the Soviet government on staff changes in the management of GOSETs in Kharkiv, Kyiv and Odesa. The author concludes the article by encouraging the study of national minority theaters for a more detailed understanding of domestic theatrical processes of the first half of the twentieth century.
COMMUNICATIVE COMPETENCE’S FORMATION IN LAW ENFORCEMENT ACTIVITY IN THE PROCESS OF EXTRAMURAL MASTERS’ PROFESSIONAL TRAINING
Authors: Zinchenko Viktoriia , Udovichenko Hannah
Published: August 2022

The article analyzes the essence of the concept of "communicative competence", considers the concept of communicative competence as a condition of effective professional activity of law enforcement, identifies components of communicative competence and their role in law enforcement, reveals the main important aspects of communicative competence of future law enforcement officers the process of professional training. It is established that a holistic system of socio-psychological means of developing communication skills contributes to the professional identity of future law enforcement officers, psychological readiness for professional communication activities. Forms and methods of work aimed at the formation of this competence in the study of the course "Communicative competence in law enforcement" for extramural masters. It is emphasized that due to the small amount of time devoted to classroom activities (8 hours), it is necessary to focus on speech (communicative) exercises, use such forms and methods of work as debate, discussion, debate. Writing of creative work on topics related to the future profession of the student / cadet, preparation of project works, etc. take out for self-directed work.
CADETS’ PSYCHOLOGICAL WELL-BEING DURING TRAINING PERIOD AT MILITARY INSTITUTIONS OF HIGHER EDUCATION
Authors: Khraban Tetyana
Published: August 2022

This empirical study describes factors that facilitate/impede the psychological wellbeing of cadets studying at Ukrainian military institutions of higher education. The preference was given to the psycholinguistic method of research, namely the free associative experiment. We argue that the most important factor for cadets’ psychological well-being is self-acceptance. When cadets correlate their self-image with professional military activity they develop healthy self-esteem and they are characterized by positive emotional states. Cadets’ failure to identify themselves with professional military activity leads to the predominance of negative emotional states. Factors such as some opportunities for personal growth and the increases the probabilities of achievement of the vital purposes are characterized by their correlation with positive aspects of cadets’ psychological well-being. A favorable psychological atmosphere in collective is another factor of cadet’s psychological well-being. The exceptions are those cadets who have inflated demands and expectations, or cadets with victim mentality. Factors such as autonomy and environmental management are characterized by their correlation with negative aspects of cadets’ psychological well-being. The high-risk category is cadets who enter the military institutions having ideal vision about military service that does not accord with reality, cadets for whom the decision to study in some military institution is made by their parents against their will, and cadets who join the army under pressure of life circumstances. The lack of personal autonomy and the inability to independently control one’s life can result in health disorders, as indicated by cadet’s emotional states of weariness, despondency, melancholy, hopelessness.
SOCIAL AND PEDAGOGICAL ACTIVITY OF THE GROMADIVTSI COMMUNITY MEMBERS IN UKRAINE (THE 2ND HALF OF THE ХІХ CENTURY)
Authors: Lysokon Illia
Published: August 2022

The article identifies the leading ideas and motives of the Ukrainian Communities, which were determined by the period of social-political changes and the formation of the modern Ukrainian nation in the context of globalization challenges. The factors influencing the activities of the Ukrainian community members have been identified. The main ideas and principles of the Ukrainian civic movement are analysed, as well as love for people as a sociocultural phenomenon and the idea of the community members for national and cultural revival. The approaches to the pedagogical activity of the Ukrainian intellectuals were revealed; the own interpretation of the concept of a "Sunday school" was offered and the peculiarities of the organization of the educational process based on liberal approaches were established. In the conditions of today's geopolitical and military challenges, it is important to understand the original idea of the national revival and to identify the main ways to achieve it. An important factor in the nation-building in the second half of the nineteenth century was the activity of the Ukrainian intelligentsia, which tried to establish ideas for national identification and self-awareness as an independent nation through the enlightenment of the masses. The community members tried to involve the inexperienced peasantry in political life peacefully, through educational and scientific activities and helped them to socialize in the new social conditions, so their activities can be divided into the categories: social-pedagogical and social-political one.
STATE POLICY DIRECTIONS IN THE FACE OF WAR CHALLENGES
Authors: Tytarenko Liubov , Yatsenko Volodymyr
Published: August 2022

The article explores the process of directing representatives of public administration in the direction of humanitarian-oriented development of the state in an era of challenges and changes during martial law. The modern world order is in a state of intensive transformation, which involves the redistribution of leverage and control over planetary resources, a globalized financial and economic system, the energy sector, the acquisition of new territories, the regulation and dominance of high-tech communications, the acquisition of control over models and mechanisms of an effective international security system. Emphasizing the problems of the orientation of the national policy of the state in the face of the challenges of war, we realize that there is a war of civilization with anti-civilization, we think that it is a balanced, responsible and effective – functioning policy requires a humanitarian and ethical basis, taking into account the best world and European experience in solving these issues. Hence the main questions that determine the effectiveness of the state's use of objective potencies of human potential a) that and in what way society, the state, the authorities can and can give people of different age categories who have fallen into difficult life circumstances as a result of the loss of home, property, life losses of relatives and friends; b) how to develop the moral and ethical worldview of citizens, and especially the younger generation, which is actively involved in defending the independence of the country in order to motivate society to rebuild the country after victory, reduce tension and aggression in the public environment. The orientation of the state policy is considered in the direction of a successful life start of young people, their personal self-determination and the realization of professional potential for the benefit of society, the state as a whole. A comprehensive solution of these and other issues is possible under the condition of a holistic, clearly verified purposeful policy of the state, the purpose of which is to coordinate the activities of all subjects of the country, to create the most favorable conditions for social adaptation of people in conditions of challenges and threats with the prospect of civilizational development of the country, humanistic changes.
RESULTS OF SURGICAL TREATMENT OF RETINAL DETACHMENTS DUE TO BLUNT EYE INJURY
Authors: Dunaieva Milana
Published: August 2022

The article analyzes the surgical treatment of 96 patients who underwent surgery for retinal detachment. The cause of retinal detachment in all cases was an eye contusion. The author analyzed the age, gender, visual acuity before and after surgery, the cause of contusion, the time of onset of retinal detachment, concomitant pathology, type of retinal tear, surgical technique, results of ophthalmological examinations in the pre- and postoperative period, postoperative complications. The factors that affect visual functions in the early and late postoperative period were determined. Visual acuity after surgery depends on the initial visual acuity. Delaying the time of surgery leads to a decrease in visual functions in the postoperative period. Proliferative vitreoretinopathy and traumatic optic neuropathy were the most common complications that led to vision loss 6 months after surgery. Traumatic optic neuropathy is the result of trauma and is not associated with surgery. There are no effective treatments. Proliferative vitreoretinopathy is a complication of surgical treatment of retinal detachment. Repeated surgical treatment does not improve vision.
Prescribing Pattern of Antidiabetic Drugs Amongst Pre-Obese Diabetic Patients in a Tertiary Care Hospital- An Observational Study
Authors: Srivastava Vartika
Published: August 2022

Background: In order to improve the prescription quality and rational prescription pattern promotion there is an inevitable need to investigate the factors that affect doctors' prescription patterns. Diabetes is a common non communicable disease. It leads to high morbidity and mortality due to the disease itself and its diverse complications like CAD, hypertension, renal complication, retinal damage, neurological disorders, generalised infections etc. With such multifactorial background of high prevalence, progressive nature of the disease, availability of multiple therapeutic regimens prescribed on trial and error basis, the treatment is individualized and neither complete nor satisfactory. Objectives: This study was undertaken to analyse the current prescribing pattern in pre-obese patients of type 2 diabetes mellitus with regard to drug/drugs precription, dose, and duration of treatment and frequency of change of drugs. Methods: This is a prospective, parallel group, comparitive observational study. The enrolled pre-obese patients were divided as a) New diabetic b) Old diabetic (<3 years duration). Each category was further divided into four subgroups according to the treatment recieved a)Monotherapy-Metforminb)Combination therapy-Metformin+another antidiabetic groups, preferably sulfonylureas, alphaglucosidase inhibitors or DPP 4 inhibitors c)Triple therapy( Metformin+SU+Voglibose or Gliptins or Glitazones) d)Insulin with other oral hypoglycemic drugs. Results: In the study of prescribing pattern, it was observed that most prescriptions in this tertiary care hospital were found to be in compliance with the ADA guidelines. Metformin monotherapy was prescribed as initial treatment. Sulphonylureas/Gliptins/Alpha glucosidase inhibitors/thiazolidinediones were used as second line therapy mostly anyone, in addition to metformin or as monotherapy according to patient requirement, tolerability and cost.Conclusions: The antidiabetic medications prescribed in this hospital, were found to be in compliance with ADA guidelines
The Pro-Inflammatory and Anti-Inflammatory Cytokines as Key Tool for Infertility Linked PCOS Diagnosis and Treatment Efficacy
Authors: Ragheb Rafik
Published: August 2022

Polycystic Ovary Syndrome (PCOS) and PCOS related ovarian dysfunction are the main causes of anovulatory infertility. POCS is estimated to have prevalence as it represents 20%-33% in the general population
Intrauterine Programming of Diabetes Induced Cardiac Embryopathy
Authors: Lister Rolanda
Published: August 2022

Background: Maternal hyperglycemia is a well-recognized risk factor for fetal congenital heart disease. However, the underlying cellular and molecular mechanisms are not well characterized. We hypothesize that maternal hyperglycemia leading to congenital heart are linked to abnormal DNA methylation and mRNA expression at cardiac specific loci. Methods: Hyperglycemia was induced in normal 8-week old CD-1 female mice with a one-time intraperitoneal injection of 150 mg/kg of streptozotocin (STZ) 2 weeks prior to mating. Histological analysis of fetal cardiac morphology was evaluated for malformations on embryonic day (E) 16.5 of control pups and pups exposed to maternal hyperglycemia. We used a massively-parallel sequencing-based methylation sensitive restriction based assay to examine genome-wide cytosine methylation levels at >1.65 million loci in neonatal hearts on post-natal (P) day 0. Functional validation was performed with real time quantitative polymerase chain reaction (RT-qPCR). Results: Cardiac structural defects occurred in 28% of the pups (n=12/45) of hyperglycemic dams versus 7% (n=4/61) of controls. Notable phenotypes were hypoplastic left or right ventricle, double outlet right ventricle, ventricular septal defect, and left ventricular outflow tract obstruction. A 10-fold increase in DNA methylation of gene promoter regions was seen in many cardiac important genes in the experimental versus control P0 neonates and have corresponding decreases in gene expression in 21/32 genes functionally validated. Conclusion: Maternal hyperglycemia alters DNA methylation and mRNA expression of some cardiac genes during heart development. Quantitative, genome-wide assessment of cytosine methylation can be used as a discovery platform to gain insight into the mechanisms of hyperglycemia-induced cardiac anomalies.
Polycystic Ovary Syndrome and a Possible Role of DietResults from a Case Control Study in Kashmiri Women
Authors: Ganie Mohd Ashraf
Published: August 2022

Background: Polycystic ovary syndrome (PCOS) management with dietary interventions targeting underlying pathogenesis of obesity and insulin resistance has been challenging for decades. Various studies so far have reported that weight loss improves ovulation, testosterone levels and insulin resistance in women but the optimal diet composition has not been evaluated in detail. Hence, the current study was undertaken with the aim to explore the role of diet in management etiology of PCOS Kashmiri women. Materials and Methods: In this case-control observational study, we randomly selected 145 PCOS patients and 145 healthy age and BMI matched controls. Dietary history was taken in detail including intake of macronutrients (fats, protein and carbohydrates) assessed by food frequency questionnaires (FFQ). Anthropometric data including weight, height, waist circumference, hip circumference and blood pressure was recorded. Patients were evaluated in detail for hirsutism, menstrual irregularity, and clinical evidence of insulin resistance. Additionally, blood samples were also collected for evaluation of clinical parameters from all the participants in this study. Results: PCOS patients had higher waist circumference, systolic blood pressure and clinical evidence of hyperandrogenism (Ferriman Gallwey Score ≥8) in comparison of controls. Complete dietary evaluation of both cases and controls revealed that though overall intake of calories was nonsignificantly higher in PCOS case, major difference was in the macronutrient composition. PCOS cases had significantly higher dietary fat intake as compared to controls(90.38 + 8.79 vs 67.98+1.92gm/day; p<0.001). However, carbohydrate and protein intake could not attain any statistically significant difference among two groups. Conclusion: Our results showed that despite similar total calorie intake fat intake is higher among PCOS cases. Thus habitual dietary fat intake increases PCOS risk, whereas proteins and carbohydrates do not have significant effect. However, more studies with increased sample size are needed to better validate the effects of dietary carbohydrates, fats and proteins on PCOS.
Genetic Factors of Diabetes Mellitus
Authors: Iqbal Rana Khalid
Published: August 2022

Diabetes mellitus is a disease in which pancreas fail to perform its work. In this condition, insulin is not produced in the amount as required for the normal function of the body. This led to different complication. And the results of many different diseases like kidney failure, high blood pressure, urination, blindness, stroke, heart attack, muscle dysfunction. Diabetes mellitus has two types: first is known as type 1 diabetes or Insulin-dependent diabetes. Second is known as type 2 diabetes or Non-insulin dependent diabetes mellitus. Most important is genetics which plays an important role in the development of diabetes. Other is environmental factors which are responsible for causing of disease by changing the gene patterns. In genetics, different genes are responsible for the causing of diabetes and these genes are present at a different position on a chromosome. In type 1 diabetes chromosome 6 and HLA complex, viral infection, physiological factors, environmental factors, and 60 genes are identified for causing of this disease. In type 2 diabetes environmental factor, 120 genetic loci, E23K polymorphism in the KCNG11 gene, Glucokinase gene mutation, epigenetics, TCF722, ABCC8, CAPN10, GIUT2, genes are responsible for the causing of disease of type 2 diabetes.
Easy Ways to Improve Diabetes and/or Obesity
Authors: Okazaki Kimihiko
Published: August 2022

Although I have an idea concerning improvement of obesity and diabetes, the idea of mine is too simple to be demonstrated as an E-poster.
Prevalence of Dyslipidemia in Patients with Type 1 Diabetes
Authors: Marques Rosana de Morais Borges
Published: August 2022

Introduction: Patients with Type 1 Diabetes tend to present premature cardiovascular disease and dyslipidemia is a relevant risk factor in this cases. Objective: To determine the prevalence of dyslipidemia and its association with glycemic control, insulin therapy, nutritional therapy of carbohydrate counting, body mass index and physical activity level in children, adolescents and adults with Type 1 diabetes. Methodology: Cross-sectional study with 87 children, adolescents and adults with Type 1 Diabetes assisted in a public hospital in Brazil. The variables studied were: age, sex, education level, blood lipid levels, glycated hemoglobin, fasting glucose, body mass index, physical activity level, insulin therapy, and the nutrition therapy of carbohydrate counting. Data were collected from medical records and analyzed in their distribution, frequency, and association with the Person’s exct chi-squared test and Fisher’s exact test (p<0,05). Results: The patients of the study were mostly adults (54%), females (64%) and, 40% concluded high school. The predominant insulin therapy was based in multiple daily injections with basal and rapid-acting analogs of insulin. The minority followed the nutrition therapy of carbohydrate counting. The prevalence of elevated glycated hemoglobin and fasting glucose was high (80,5% and 73,3%, respectively). Obesity was observed in 4,6% of adults. Regarding the blood lipid levels, hypercholesterolemia and low levels of HDL-c were observed in all age categories. Dyslipidemia was not associated with the variables of the study. Conclusion: There was observed dyslipidemia in all age categories of the patients of the study. Most of them were not following the nutrition therapy of carbohydrate counting and presented poor glycemic control. These two last caracteristics are modifiable and more educational activities should be developed to encourage self-care and prevent premature diabetes complications like cardiovascular diseases.
Weight Loss through Vinyasa Flow Yoga - A Pilot Feasibility Study in Singapore
Authors: Palaniappan Kavitha
Published: August 2022

Obesity has become an increasing concern in the world and has also become a public health threat in many countries. Governments and private sectors are working hard to develop various strategies to assist people to have a better control over their health. Regular exercise, which is part of a healthy lifestyle help to improve cardiovascular health, leading to weight loss and hence prevention of certain potential illnesses. Yoga, being one of the physical exercises, promotes body’s natural harmony and functional balance, which in turn, helps individuals to live a better life. This paper outlines the pilot study conducted in Singapore to investigate the effects of Vinyasa Flow Yoga coupled with Pranayama on the weight-related outcomes in adults, in particular, reduction of body weight and body fat percentage. The results show that weekly Yoga practices impose positive results on the reduction of body weight and fat percentage, and hence can be considered essential for a healthy lifestyle.
Dual burden of Tuberculosis (TB) and Diabetes Mellitus (DM) as the major risk factor for wide range of population
Authors: Meena Laxman S
Published: August 2022

The bidirectional association between tuberculosis (TB) and diabetes mellitus (DM) creates a dual burden of these diseases globally. DM patients have chronic infections more often than those without DM and one of the possible causes is a compromised immune system that can lead to various persistent infections. This correlation creates special attention and thus the detailed study of the human immune system and needs to develop some good strategies for the prevention of diabetes in patients who are exposed to Mycobacterium tuberculosis (MTB). Both diseases are negatively affecting each other as patients taking diabetic drugs may interact with Anti TB drugs which may decrease the efficiency of drugs and on the other side patients having tuberculosis may be prone to hyperglycemic condition. In this mini-review, we tried to describe the bidirectional association of TB and DM’ and possible mechanisms by which a diabetic patient develops active TB and TB patients develop DM. Reducing diabetes could potentially reduce individual-level risks of TB and ultimately prevent increases in TB population incidences.
A Study on Death Prevalence due to Obesity in Nigeria from 1990 to 2017
Authors: Khanam Sabina
Published: August 2022

Obesity is a public health problem globally. There are several other communicable diseases such as malaria, measles, HIV etc. are prominent contributors to diseases burden in Africa, but now this disease burden transfer to other noncommunicable diseases such as obesity, respiratory diseases, cancer, cardiovascular diseases etc. This study was conducted to examine prevalence of deaths due to obesity in Nigeria from 1990 to 2017. The data of total population and total deaths reported from 1990 to 2017 were collected from various internet websites. Significant highest death prevalence rate was found in the year 2000 (0.0196%) in that year the total population of Nigeria were 12,22,83,850, and total deaths were 23,984. Significant lowest death prevalence rate was found in the year 2013 (0.0129%) in that year the total population of Nigeria were 17,45,07,539 and total deaths were 22,679.
Does Diabetes and Hypertension have Common Pathophysiology - A Study
Authors: Daivasikamani Premkumar
Published: August 2022

Diabetes and hypertension often occur together. Hence they may share some common causes. These causes may be obesity, inflammation, oxidative stress and insulin resistance. Type 2 diabetes may cause hypertension by atherosclerosis. It suggests the importance of keeping an optimal glycaemic profile in general populations. BP screening and monitoring, especially systolic BP, is essential in patients with type 2 diabetes. There are many theories and there is no confirmed mechanisms but, genetic predisposition, insulin resistance, inflammation, oxidative stress, endothelial dysfunction, and have been suggested to explain the link between higher hypertension and diabetes. In our study it was found that 51.8 percent had normal blood sugar and 19% are pre diabetic and 29% are diabetic. As the age increases the incidence of prediabetes and diabetes also increases. Incidence of Diabetes is more in males than in females. Similarly, the prediabetes is also more common in males. Among females 10.75% had normal blood sugar and normal BP and among Males only 3.7% had normal blood sugar and normal BP. Females are more in the prediabetes and elevated & Stage I BP and more males are diabetic and hypertensive.