bluuebunny/crossref_metadata_2025 huggingface dataset:
Recent insights on principles of synaptic protein degradation
Authors: Cohen Laurie D. , Ziv Noam E.
Published: May 2017

Maintaining synaptic integrity and function depends on the continuous removal and degradation of aged or damaged proteins. Synaptic protein degradation has received considerable attention in the context of synaptic plasticity and growing interest in relation to neurodegenerative and other disorders. Conversely, less attention has been given to constitutive, ongoing synaptic protein degradation and the roles canonical degradation pathways play in these processes. Here we briefly review recent progress on this topic and new experimental approaches which have expedited such progress and highlight several emerging principles. These include the realization that synaptic proteins typically have unusually long lifetimes, as might be expected from the remote locations of most synaptic sites; the possibility that degradation pathways can change with time from synthesis, cellular context, and physiological input; and that degradation pathways, other than ubiquitin-proteasomal-mediated degradation, might play key roles in constitutive protein degradation at synaptic sites. Finally, we point to the importance of careful experimental design and sufficiently sensitive techniques for studying synaptic protein degradation, which bring into account their slow turnover rates and complex life cycles.
Pneumocystis jirovecii detection in asymptomatic patients: what does its natural history tell us?
Authors: Alanio Alexandre , Bretagne Stéphane
Published: May 2017

Pneumocystis jiroveciiis an unusual ascomycetous fungus that can be detected in the lungs of healthy individuals. Transmission from human to human is one of its main characteristics in comparison with other fungi responsible for invasive infections.P. jiroveciiis transmitted through the air between healthy individuals, who are considered to be the natural reservoir, at least transiently. In immunocompromised patients,P. jiroveciimultiplies, leading to subacute infections and acute life-threatening pneumonia, called Pneumocystis pneumonia [PCP]. PCP is caused by genotypically distinct mixtures of organisms in more than 90% of cases, reinforcing the hypothesis that there is constant inhalation ofP. jiroveciifrom different contacts over time, although reactivation of latent organisms from previous exposures may be possible. Detection ofP. jiroveciiDNA without any symptoms or related radiological signs has been called “colonization”. This situation could be considered as the result of recent exposure toP. jiroveciithat could evolve towards PCP, raising the issue of cotrimoxazole prophylaxis for at-risk quantitative polymerase chain reaction (qPCR)-positive immunocompromised patients. The more accurate way to diagnose PCP is the use of real-time quantitative PCR, which prevents amplicon contamination and allows determination of the fungal load that is mandatory to interpret the qPCR results and manage the patient appropriately. The detection ofP. jiroveciiin respiratory samples of immunocompromised patients should be considered for potential risk of developing PCP. Many challenges still need to be addressed, including a better description of transmission, characterization of organisms present at low level, and prevention of environmental exposure during immunodepression.
Harnessing the immune response to target tumors
Authors: Manning Luisa , Nemunaitis John
Published: May 2017

Development of “immune-based targeted therapy” in oncology has limited experience with signal pathway modulation. However, as we have become better versed in understanding immune function related to anticancer response, “hints” of specific targets associated with sensitivity and resistance have been identified with targeted immune therapy. This brief review summarizes the relationship of several targeted immune therapeutics and activity associated clinical responsiveness.
Yin and yang of interleukin-17 in host immunity to infection
Authors: Das Shibali , Khader Shabaana
Published: May 2017

The interleukin-17 (IL-17) family cytokines, such as IL-17A and IL-17F, play important protective roles in host immune response to a variety of infections such as bacterial, fungal, parasitic, and viral. The IL-17R signaling and downstream pathways mediate induction of proinflammatory molecules which participate in control of these pathogens. However, the production of IL-17 can also mediate pathology and inflammation associated with infections. In this review, we will discuss the yin-and-yang roles of IL-17 in host immunity to pathogens.
Parallel pathways in the biosynthesis of aminoglycoside antibiotics
Authors: Yu Yi , Zhang Qi , Deng Zixin
Published: May 2017

Despite their inherent toxicity and the global spread of bacterial resistance, aminoglycosides (AGs), an old class of microbial drugs, remain a valuable component of the antibiotic arsenal. Recent studies have continued to reveal the fascinating biochemistry of AG biosynthesis and the rich potential in their pathway engineering. In particular, parallel pathways have been shown to be common and widespread in AG biosynthesis, highlighting nature’s ingenuity in accessing diverse natural products from a limited set of genes. In this review, we discuss the parallel biosynthetic pathways of three representative AG antibiotics—kanamycin, gentamicin, and apramycin—as well as future directions towards the discovery and development of novel AGs.
Novel approaches to HIV therapy
Authors: Daar Eric S.
Published: May 2017

There are approximately 35 million people infected by human immunodeficiency virus (HIV), with an estimated 2 million incident infections annually across the globe. While HIV infection was initially associated with high rates of morbidity and mortality, advances in therapy have transformed it into a chronic and manageable disease. In addition, there is very strong evidence that those on antiretroviral therapy are much less likely to transmit infection to their partners. The success rates for maintaining viral suppression in treated patients has dramatically increased owing to the development of agents that are potent and well tolerated and can often be co-formulated into single pills for simplification. This review will outline advances in treatment over the last several years as well as new strategies that may shift the existing treatment paradigm in the near future.
Case Report: Multiple hemorrhagic metastases to the brain from primary lung choriocarcinoma
Authors: Munakomi Sunil
Published: May 2017

Herein we report a very rare entity of multiple hemorrhagic metastases to the brain from a primary lung choriocarcinoma in a young woman. The patient presented with recent onset of progressive headache, decreased level of consciousness and multiple episodes of vomiting. CT of the head revealed multiple hemorrhagic lesions within the brain. The patient’s serum B-human chorionic gonadotrophin was increased.  A chest X-ray revealed a right lung mass. The patient urgently underwent operative excision of the lesion in the posterior fossa, so as to prevent impending tonsillar herniation. The histology from the lesion provided the diagnosis of choriocarcinoma. After surgery, ultrasonography of the abdomen and pelvis was normal, and a chest CT revealed an enhanced and highly vascular right apical lung lesion, suggestive of lung primary choriocarcinoma, with regard to the clinical background. The patient was then started on chemotherapy, following which her serum B-HCG level decreased rapidly. This case highlights the importance of keeping this entity in the differential diagnosis of hemorrhagic lesions in any patients of a child bearing age. Early diagnosis and rapid initiation of multimodal therapy is prudent for ensuring a good outcome from an otherwise rapidly metastasizing and highly vascular lesion.
CONTRADICTION ASH-AND-SLAG OF TPP
Authors: Безгласный Кирил , Bezglasnyy Kiril , Скориков Роман , Skorikov Roman , Шаля Артем , Shalya Artem , Овчинников Р , Ovchinnikov R , Авакян Арсен , Avakyan Arsen , Потехин Алексей , Potekhin Aleksey
Published: May 2017

This article shows the obstacles of using thermal power plant’s ash waste on an industrial scale.

The results of determining the activity of fly ash and hydroremoval ash in a mixture with Portland cement are given.

Schemes of translation ash from the category of waste with heterogeneous characteristics in the raw material with stable properties are offered. The most rational ways of using ash from thermal power plants in building materials are presented
DEVELOPMENT OF CONSTRUCTIVE SOLUTIONS VERTICAL REINFORCED BASES OF SLAB FOUNDATION OF HIGH-RISE BUILDINGS IN SEISMIC AREAS
Authors: Мариничев Максим , Marinichev Maksim , Ткачев Игорь , Tkachev Igor
Published: May 2017

The article presents the results of a numerical simulation of the behavior of high-rise building on weak clay soils, during which the deformations of different variants of foundations were analyzed. The main variants of foundations were examined: slab, traditional pile-slab construction and pile foundation with an intermediate base. Series of numerical calculations in spatial statement determine the deformability of the "Base" - "Structures of the building"- system revealed a favorable response for the use of the intermediate base between the piles and foundation slab of the building. Variant of pile foundation with an intermediate base (vertical reinforced base of slab foundation) allowed not only reduce the absolute deformation of base of the building, but also reduce the effort in the pile elements compared to the traditional pile-slab foundation. Therefore, it was proposed as the most rational for this building
ABOUT THE MODE INFLUENCE OF APPLYING SHOCK LOADS ON THE INDICATORS OF COMPACTIBILITY OF CLAY LOAM
Authors: Монтаева Хасият , Montaeva Khasiyat , Байтемиров Мухан , Baytemirov Mukhan , Бекбасаров Исабай , Bekbasarov Isabay , Исаков Галым , Isakov Galym
Published: May 2017

The results of tests of samples of clay loam on the effects

of different modes of applying multiple shocks are presented. The

influence of shock loading conditions on the deformability of the samples, their density and power consumption of upcompaction are assessed. Revealed that the highest density is typical for samples compacted at a linearly increasing load conditions, and the lowest – at constant load conditions.
THE SHEAR RESISTANCE OF THE SOIL WHEN RE-LOADING THE SAMPLE
Authors: Гохаев Дмитрий , Gohaev Dmitriy , Шмидт О , Shmidt O
Published: May 2017

They briefly reviewed the information about the processes occurring in the microstructure of clay soil when reporting it shear deformations. They made monoplanar cuts of two groups of clay soil samples in the shift device by applying a compressive load.

The samplesofthe first group were tested on cutting by repeated application

of the vertical force. While testing the second group of samples the vertical compressive load was applied only once. As a result of the evaluation of test data, there was obtained a soil reinforcement by re-loaded samples as compared with single-loaded.

This received under repeated loading vertical force hardening, presumably, could be due to an increase in the total area of the sliding surfaces, along which there occurs the deformation of the samples. The resulting effect can be used in designing remodeling.
Magnetic resonance properties of nano granular magnetic films with carbon matrix
Authors: Вызулин  , Vyzulin Sergey , Кевралетин  , Kevraletin Aleksandr , Сырьев  , Syrev Nikolay
Published: May 2017

We investigated granular magnetic resonance characteristics nanocomposite magnet systems (CoFeB)m-С100-m and и (CoFeB)m-(SiO2)100-m. The ferromagnetic resonance spectrum of the samples (CoFeB)m-С100-m extra observed (compared with the system (CoFeB)m-(SiO2)100-m) of the absorption line. Analysis of experimental data shows that the dominant factor in determining the characteristics of the magnetic resonance system (CoFeB)m-С100-m, synthesized by the method of ion-plasma spraying is the formation for the synthesis of nanoparticles of iron carbide and/or cobalt.
Excitation of magnetostatic surface waves by symmetric coplanar line
Authors: Бабичев  , Babichev Rudolf , Левендорский  , Levendorskiy K. , Бабичева  , Babicheva G.
Published: May 2017

An excitation of magnetostatic surface waves (MSSW) with a symmetric coplanar transmission line was considered for the case, when coplanar line is placed at some distance from the ferrite film surface. The dependence of symmetric coplanar line impedance on the spacing between the line and ferrite film has been studied for the case of magnetostatic surface waves. It has been found that smaller values of this spacing cause increase the frequency range of effective MSSW excitation. Narrow bandwidth insertion loss filters can be achieved by use shorted one screen coplanar transducers.
Band-pass filter based on magnetostatic surface waves, exciting by a one screen coplanar line
Authors: Бабичев  , Babichev Rudolf , Левендорский  , Levendorskiy K. , Натхин  , Natkhin I. , Тахтамышьян  , Takhtamyshyan V.
Published: May 2017

An excitation of magnetostatic surface waves (MSSW) by a one screen coplanar transmission line was considered for the case, when coplanar line is placed at some distance from the ferrite film surface. The dependence of coplanar line impedance on the spacing between the line and ferrite film has been studied for design of band-pass filter. Approximate theoretical method of band-pass filter design is presented. Experimental frequency responses of band-pass filter which utilize a yttrium-iron-garnet (YIG) films with different thickness are presented and compared. Frequency dependences of a one screen coplanar line radiation resistance and insertion losses of band-pass filter are discussed.
Nano-magnetic materials for rotors of high-speed and of over-high-speed electromechanical energy converters
Authors: Останин  , Ostanin S. , Миляев  , Milyaev I.
Published: May 2017

The "Nano-magnetic materials for rotors of high-speed and of over-high-speed electromechanical energy converters" are developed issues of choice and of research of magnetically hard materials and alloys for rotors of the high-speed and of the ultra high-speed hysteretic electromechanical energy converters; impact of heat treatment modes, hot plastic deformation and sintering temperature on the magnetic, hysteretic properties and characteristics of the base class´s alloys.
Experimental investigation of magnetic field near strip conductors with rectangle cut-out
Authors: Муравьев  , Muravev A. , Поляков  , Polyakov Petr , Герасименко  , Gerasimenko T. , Касаткин  , Kasatkin S. , Русакова  , Rusakova N.
Published: May 2017

A theoretical distribution of magnetic field generated by strip conductors of different widths close to a rectangular cutout is derived. An experimental investigation of strip conductor magnetic field with magnetoresistive and Hall sensors based devices is presented. The experimental results fit the theoretical calculations. A method of conductor defect detection using appliances based on the sensors was developed.
Special aspects of electric charge distribution on conductor surface with shape transformation
Authors: Поляков  , Polyakov Petr , Самухина  , Samukhina Yuliya , Русаковка  , Rusakovka N.
Published: May 2017

Few analytical solutions of the electrostatic problem for charge distribution on a conducting body surface are known nowadays. In the paper several new non-trivial forms of conducting bodies that afford an exact analytical solutions were derived. 2D and 3D graphics were plotted as a result of analysis of the solutions. It was also shown that the method in the paper allows to derive infinite solution sets of the problem for charge distribution on a conductor surface within four classes.
Thermo-physical studies of porous structures for heat sink design.
Authors: Крахин  , Krakhin Oleg , Прокофьев  , Prokofev Mikhail , Радченко  , Radchenko V.
Published: May 2017

The variant of thermo-physical calculations of heat pipes and properties of the ceramic capacitors were performed. For optimal use of loop heat pipe the values of the required volume of fluid in the heat pipe and the influence of filling degree on the conditions of vaporization were defined. The calculations are performed using the known from literature correlations based on thermodynamic properties of working fluids, the parameters of porosity of the condenser and evaporator. The calculation results allowed us to formulate specific recommendations for the implementation of thermal cooling heat-loaded electronics. Formulated recommendations for the design of heat pipes based on ceramic materials and porous metals, according to which the use of ceramic capacitor with high porosity provides the possibility of increasing the steam against the forces of gravity, and metal-ceramic materials create the conditions to reduce the weight and size parameters of the heat pipe.
FUNDAMENTALS OF GEOTECHNICAL AND SOIL MECHANICS
Authors: Кулачкин Борис , Kulachkin Boris
Published: May 2017

The basic position (category) of the new soil mechanics

and geotechnical engineering, are set out in hierarchical order

and systematized. The article gives the fundamental differences

of new developments on existing, including the new classification

of the ground state (compaction — normalnouplotnenny — nedouplotnenny),

geotechnical model (geomassiv — the foundation —

building), weight of the soil (assessment γh in situ), the pore

pressure (education element and evolution of the lithosphere),

analogue-discrete soil model (frail body with an infinite elastic

modulus), Young’s modulus (modulus of elasticity), capillary soil

model (beaded capillaries and capillaries Zhomena), the effect

Kulachkina-Radkevich (pore pressure may be lower than atmospheric

pressure, load-bearing capacity (Gersevanov and acoustics

in the ground), the acoustics in geotechnics (continuity, integrity,

strength and geometry of the pile, and others). The analytical

and experimental data in various regions of Russia and abroad

are given.
Obtaining anisotropic hexagonal ferrites for substrates microstrip microwave devices of mm-range of radiation thermal sintering
Authors: Пашков  , Pashkov A. , Костишин  , Kostishin V. , Исаев  , Isaev I. , Читанов  , Chitanov D. , Комлев  , Komlev A. , Щербаков  , Shcherbakov S. , Налогин  , Nalogin A. , Алексеев  , Alekseev A. , Белоконь  , Belokon E. , Брязгин  , Bryazgin A. , Коробейников  , Korobeynikov M. , Михайленко  , Mikhaylenko M.
Published: May 2017

We obtain polycrystalline hexagonal ferrite substrate of subminiature devices microstrip ferrite decoupling short-wave part of the centimeter and millimeter wavelength radiation and thermal sintering. A feature of the manufacture of anisotropic hexagonal ferrite technology radiation-thermal sintering is pressing in a strong magnetic field applied in the direction of compression, which allows target particles and to obtain a material with a high degree of texture, and the use of various compounds and dopants in the manufacturing process, allows you to control electromagnetic and magnetic hexagonal ferrites.
Katkons in transformer schemes
Authors: Бутырин  , Butyrin P. , Шакирзянов  , Shakirzyanov F. , Гусев  , Gusev G. , Михеев  , Mikheev D. , Наумова  , Naumova A. , Кольцун  , Koltsun O.
Published: May 2017

Macromodels of transformers with different types of relationships (not only inductance but also capacitance) on the basis of circuits with quasi-distributed parameters simulation were proposed. The analysis of resonant modes and frequency characteristics of transformers on the basis of katkons with identical parameters at the open and closed secondary circuit were obtained. Results of the study will help to evaluate the effectiveness of the practical application of these transformers to improve power factor and efficiency of the transmission, distribution and conversion of electric energy. Using the correct transformers macromodels on the bases of katkons with strong and weak coupling makes possible to realize polyfunctional filter-compensative devices and current-limiting devices with reduced weight and dimensions.
FEATURES OF FORMATION AND MANAGEMENT OF STAFF QUALITY IN GERMANY AND RUSSIA
Authors: Кудайберген  , Kudaybergen Pirimkul
Published: May 2017

The article reveals peculiarities of the German and Russian staff, the tradition of quality of formation personnel in Germany and the Russian Federation. The impact reveals social protection, promotion, and the inevitability of punishment on the quality of the German staff. For example, compare the quality of the metro station and staff in Moscow and Dortmund, there is shown the differences in the activities of personnel in Germany and Russia. The origins and reasons for the relatively poor quality of Russian personnel are settled.
PLACE OF PERFORMANCE MEASUREMENT IN THE MANAGEMENT SYSTEM OF THE ORGANIZATION
Authors: Еремина  , Eremina G. , Соболь  , Sobol O.
Published: May 2017

The article analyzes the existing western approaches to the evaluation of performance indicators, which are now actively used in Russia: Management by Objectives, Balanced Scorecard, a system for assessing key performance indicators, etc. The work of domestic authors is also considered, dedicated to measuring financial performance and evaluation of staff. The article deals with the main concepts related to measuring performance: «key performance indicators» (KPIs), «key results indicators» (KRIs) and etc. The research showed that in most cases companies use existing methods to measure their performance, aimed at assessing financial indicators or qualifications, knowledge, skills of employees. In turn, the methods of measuring effectiveness and effectiveness, which allow to reflect the level of achievement of the set goals, the degree of effectiveness of the activities of personnel and the organization as a whole, provide feedback to employees on key areas of their actions are in demand less. The article also provides the basic rules for the application of the performance measurement system, which makes it possible to improve the efficiency of its application.
MANAGEMENT OF LABOR MOTIVATION: CURRENT PROBLEMS WITH REGARD TO THE HISTORICAL FOUNDATIONS
Authors: Смирнова  , Smirnova M.
Published: May 2017

Effective management is impossible without understanding motives and human needs. The author believes that the way to effective management of labor behavior of employees is through building a systematic approach to work motivation of employees, contributing to increase the staff interest in the results of their work. Depending on whether satisfied or not the motive is at work, the person formed a positive or negative assessment of the conditions and content that is, or that the degree of job satisfaction. Motive — an inner drive or impulse that causes a person to act a certain way. It is connected directly with satisfaction of human needs: physiological, spiritual, economic and other. Motivation is the main and effective lever for productivity growth in the organization.
EMPIRICAL ANALYSIS OF THE IMPACT OF ORGANIZATIONAL ENVIRONMENT ON POTENTIAL OF PROACTIVE EMPLOYEE
Authors: Семенова  , Semenova I.
Published: May 2017

The ability and willingness of the employee consciously manage the quality of their potential and to initiate positive changes in the organization, contributing to its success, it stands a real driving force for development and sustained competitiveness of contemporary companies. In this regard, topical focus of research is the study of institutional mechanisms that ensure maximum disclosure of the potential of proactive employee (PPE) for the organization. The research methodology is based on the provisions of self-leadership and individual initiative concepts, the concept of self-organizing self-developing systems (2C-systems). Methods of study: a survey of employees of an international network of stores implementing perfumes, cosmetics brands in the city of Perm. Data were analyzed using PLS-analysis using SmartPLS program. Results. It was found that the most significant positive impact on the PPE to provide organizational leadership as the driving force of the professional activity of employees; system development and training as an opportunity for the formation of the unique competencies of employees; organizational culture of the company as a «translator» of the idea of creativity and initiative of employees. The smallest impact on proactive behavior of employees providing the organization’s management structure and motivation system. The results of this research can be used to monitor the internal environment and to identify organizational barriers to enterprising behavior of workers in the general staff, and specific target groups of employees.
METHODS FOR EVALUATING THE EFFECTIVENESS OF THE MOTIVATION SYSTEM FOR THE PERSONNEL OF A TOURIST AND RECREATIONAL ENTERPRISE
Authors: Столяренко  , Stolyarenko Alyona
Published: May 2017

The article is devoted to the search for the most effective approach to the evaluation of the effectiveness of the motivation system of the personnel of a tourist and recreational enterprise. The main goal of the effective system of personnel motivation is defined in the work — formation of the correct interrelations of the elements of the system aimed at achieving the set goal of the enterprise. In the presented work approaches to the evaluation of the effectiveness of the staff motivation system through application of specific methods of personnel assessment, based on the implementation of the list of requirements for it, are investigated. The need for a correlation between the selection of a specific method of staff assessment, for the purpose of evaluation, was stressed. The main quantitative and qualitative indicators aimed at assessing the effectiveness of the system of motivation of the personnel of the enterprise, namely: length of service, education, age, turnover of staff, benefits and additional payments, encouragement and punishment, etc. In terms of identifying staff needs and determining the degree of satisfaction, the best Method — the construction of a motivational profile.
Advertizing
Authors: Музыкант  , Muzykant Valyeriy
Published: May 2017

The hand book deals with the different aspects of advertising. Advertising process is considered as an important part 4 P’s, and integral part of brand creativity. Advertising creates brand assets, based on the financial reserves and legal protection of the brand, its emotional / rational / functional capital, successful positioning and other key attributes. Advertising and promotion always influence the target audience in Pre-market as well as in the market era. The author, Professor V.L.Muzykant, a well-known Russian specialist in marketing, branding, advertising, thoroughly analyzed the advertising position during campaigning. Special focus is being made to a set of associations, creates in the minds of the target audience a concept based on the consumer's comparative evaluation of company's brand with competing trademarks.
Definition of causes of destruction of materials of a bricklaying on sites of facades of buildings under construction of the residential quarter in the residential district "October" of Novocherkassk of the Rostov region.
Authors: Субботин Анатолий , Subbotin Anatoliy , Субботин Виталий , Subbotin Vitaliy , Субботин Игнат , Subbotin Ignat
Published: May 2017

IThis article discusses the problem related to the appearance of defects in masonry cladding layer self-supporting walls of buildings with monolithic concrete frame for example inspection of buildings under construction of residential quarters in the October district of Novocherkassk. As a result of the survey by OOO "STC" identified and described the characteristic defects in the veneering layer self-supporting walls of buildings and identify their causes. Based on the experience of experts, instrumental studies of structural materials, conducted by a certified testing laboratory in materials survey gives an overview of the causes of defects are manifestations of research of other spe-cialists and organizations leading of which is CNIISK. VA Kucherenko. According to the results of the system analysis of detected defects and data instrumental studies, the authors proposed solutions to eliminate the defects and bring the building up to standard.
MODELING CONSTRUCTION OF MONOLITHIS CONCRETE FLOORS TAKING INTO ACCOUNT ORGANIZATIONAL - TECHNOLOGICAL RELIABILITY
Authors: Лебедев  , Lebedev Vladimir , Беликова  , Belikova Galina
Published: May 2017

Work out the organizational and technological models and carried out in-line construction complex engineering preparation of construction production construction of monolithic concrete floors, taking into account the organizational and technological reliability
EVOLUTION OF AMERICAN OPTION VALUE FUNCTION ON A DIVIDEND PAYING STOCK UNDER JUMP-DIFFUSION PROCESSES
Authors: Рехман  , Rekhman Nazir , Хуссейн  , Khusseyn Zakir , Али  , Ali Faykha , Бендерская  , Benderskaya Olga , Хуссейн  , Khusseyn Sultan , Зуев  , Zuev Sergey
Published: May 2017

This work is devoted to the analysis and evolution of the value function of American type options on a dividend paying stock under jump diffusion processes. An equivalent form of the value function is obtained and analyzed. Moreover, variational inequalities satisfied by this function are investigated. These results can be used to investigate the optimal hedging strategies and optimal exercise boundaries of the corresponding options.
The New on the Russian Financial Market
Authors: Смирнов  , Smirnov E.
Published: May 2017

In the current year, federal laws of July 3, 2016 № 262-FZ and June 23, 2016 № 215-FZ come into operation in full force, adopted last year in the interests of further increasing of the transparency of business and legal order in the financial market of Russia.
Tax Audit Features
Authors: Ерыгина  , Erygina L. , Золотарева  , Zolotareva G. , Денисенко  , Denisenko Galina
Published: May 2017

The article substantiates the demand for tax audit in Russia, reviews the scientific literature on the terminology and procedure for conducting tax audit, presents the results of analysis of tax audit techniques used in domestic practice, substantiates the need to use different methods when conducting inspections of specific types of taxes.
Antibribery Management: Anticorruption Compliance Controls in Organization
Authors: Черепанова  , Cherepanova Vera
Published: May 2017

In the article the author provides a review of the concept of bribe and its types in the context of Russian and international exterritorial anticorruption legislation. The article discusses the forms under which bribery may appear in day-to-day business operations of an organization.
Analysis of marital status in the Republic of Sakha (Yakutia) for 2015: program-project approach
Authors: Комаренко  , Komarenko Tat'yana
Published: May 2017

The analysis of marriage and family relations in the Republic of Sakha (Yakutia) shows that decreasing the number of marriages, in 2016 the number of registered marriages amounted to 6297. The number of divorces in 2016 was 4162. That is, in 6297 registered marriages in the country during the last three years in 2016 year account for 66% of divorces. In recent years, the number of acts of name change has a strong tendency to increase. Today, in the Republic of Sakha (Yakutia), the population amounted to 963 thousand. Man. Natural population growth in the January 1, 2016 amounted to 8180 people. In 8165 16,345 births account for the dead man.
METHODOLOGICAL BASES DEVELOPMENT OF SOCIO-ECONOMIC SYSTEMS MODELING IN THE CONTEXT OF DEVELOPMENT MANAGEMENT
Authors: Андриянов Сергей , Andriyanov Sergey
Published: May 2017

Complexity of economic systems modeling for ef-ficiency assessment of their functioning and elabora-tion of development forecasts can be explained by a number of factors. One of them is heterogeneity of economic systems, significant dependence of their structure and principles of key elements interaction on the management level, industry membership, the scope of system work. Vector and development dynamics of socio-economic system are determined, on the one hand, by internal potential of its elements , each im-plements its own development trajectory on the micro-level, and on the other hand – by opportunities of the external environment which is characterized by a com-plex mix of macroeconomic, political, social, technolo-gical and natural factors.

Analysis of the existing development

methods of economic systems models at different levels allows marking out several modeling technologies among which the most promising from the point of view of application in real management practice can be considered the technology of imitation modeling based, in turn, on three methodological approaches.

For the solution of a modeling problem of regional socio-economic system combined approach application appears to be the most effective within which external macroprocesses are modeled by means of system dynamics, and internal – socio-economic processes are formalized by agent-based modeling methods.
APPLICATION OF EDUCATIONAL SERVICES MARKETING IN EDUCATIONAL INSTITUTIONS
Authors: Горностаева Алла , Gornostayeva Alla
Published: May 2017

The purpose of the work is to consider problems of marketing application of educational services in the Russian educational institutions activity, to reveal pre-requisites of relevance strengthening of these problems on the market of educational services, especially the system of advanced training of heads and experts; to show that application of methodology of strategic and marketing management in practice is caused by the objective reasons which are defined by character of the changes, first of all in the organization environment.

In the course of research strategic marketing and management methods are used.

The studies show that the most important task of strategic management of the educational institution is establishment and maintenance of dynamic interaction of the organization with the environment surrounding it.

Conclusions: strategic management is intended to provide the organization long-term survival, competi-tive advantage is reached due to delivery of products or services to the consumer satisfying their requirements; cooperation problem of higher education institutions and industrial enterprises in which marketing takes a position of one of the leading functions of creating conditions for successful functioning and development of the organization, is especially urgent at present.
PROBLEMS OF INNOVATIVE STRATEGY FORMATION OF ECONOMIC ENTITIES TAKING INTO ACCOUNT MODERN REQUIREMENTS OF THE MARKET ENVIRONMENT
Authors: Козлова Евгения , Kozlova Evgenia
Published: May 2017

The formation mechanism of the innovative strat-egy of economic entity offered by the author includes the following stages: the analysis of macro- and micro-environment factors; the analysis of innovative poten-tial of the managing system; marketing and investment analysis of the innovative projects; working out innovative development strategy; drawing up the passport of innovative development and acceptance of administrative decisions on its basis; the analysis and control of the efficiency of implementing a chosen innovative strategy. Reasonable innovative strategy will allow the en-terprise to adapt quickly to the changing environmental conditions, to reduce the risk level of introducing innovative activity, to define the directions of the enterprise development in the innovative field competently and also to concentrate administrative efforts in order to achieve strategically important tasks.
APPLICATION OF LOGISTICS SYSTEMS IN MACHINE-BUILDING ENTERPRISES
Authors: Коченкова Наталья , Kochenkova Natalya
Published: May 2017

The use of logistic approach at machine-building enterprises has considerable results. The application of tools and methods "kaidzen" and lean production al-lows to achieve substantial efficiency increase of en-terprise activity, labor productivity, improvement of product quality and growth of competitiveness without considerable capital investments.

These logistic systems are implemented success-fully at the Russian machine-building enterprises. JSC Lyudinovsky Locomotive Works successfully realizes the quality system "5 S kaidzen", and SA "UK "BMZ" in April, 2016 has received certificate of compliance for the Quality management system of Economical production. These systems have allowed to reduce losses considerably and to increase product quality.

Thus, applying the logistic approach in the organi-zation of production processes at machine-building enterprises leads to improvement of product quality, increase in competitiveness both on internal and on international markets.
INNOVATIVE DEVELOPMENT IN THE CONDITIONS OF ENSURING ECONOMIC SECURITY OF THE REGION
Authors: Кулагина Наталья , Kulagina Natalya
Published: May 2017

In modern conditions of economy development and strengthening of globalization processes in the world space one of the most urgent problems of the Russian Federation is the national interests’ safety that assumes improvement of the managing mechanism of certain territorial subjects of the federation according to the Strategy of national security of the country. One of the leading roles in this case is assigned to innovative production by an industrial complex of economy which will provide competitiveness of national economy in accordance with the needs of world consumers. The integration of the efforts of regional authori-ties and business owners has to become the practical purpose of the management mechanism of the industrial potential of the Bryansk region. It is aimed at efficiency increase of industrial potential use due to implementation of "new" industrial policy, based on intensification of innovative activity, increase of science and production interaction, improvement of the state support mechanisms.
SOCIO-ECONOMIC MEASURES OF SOUTHWEST AREAS DEVELOPMENT OF THE BRYANSK REGION, MOST AFFECTED BY CHERNOBYL DISASTER
Authors: Ларичева Елена , Laricheva Elena
Published: May 2017

The population of southwest regions of the Bryansk region (Novozybkovsky, Krasnogorsk, Zlyn-kovsky, Gordeevsky, Klintsy, Klimovsk and Starodub regions) was most exposed to radiation from the Cher-nobyl accident.

For reducing social and economic consequences of the accident it is necessary to increase population welfare, to create a social and attractive business envi-ronment, to promote innovative development of the industry, increase of the birth rate, growth of life ex-pectancy of citizens, formation of civil society, and also to control the city and the region effectively.

The article distinguishes the main socio-economic

problems of southwest regions of the Bryansk region, such as poor production development, low level of the salary, low level of investment into the fixed capital, poor health care, leaving of youth, etc.

For development of southwest regions of the Bryansk region it is necessary to increase enterprise activity through creation of industrial and agro-industrial clusters. It is also recommended to create Centre of economic development of southwest regions of the Bryansk region and transport-logistical center.
STATISTICAL JUSTIFICATION OF SWOT ANALYSIS OF PERSONNEL PROCESSES IN A QUALITY MANAGEMENT SYSTEM OF THE ORGANIZATION
Authors: Можаева Татьяна , Mozhaeva Tatyana
Published: May 2017

According to requirements of the ISO 9000 new standards of 2015 version process management in a quality management system (QMS) of the organization provides interrelation of three factors: their planning, realization of PDCA cycle and the risk-focused thinking including the evaluation of environmental factors influence which can lead to the deviation from the planned results and also minimize negative consequences and maximize emerging opportunities. ISO 9001 standards : 2015 don't contain requirements for application of concrete techniques of the evaluation of environmental factors influence, and the organization can choose the tool which satisfies its requirements. The international ISO 31000 standards containing the general guidelines on the identification, management and the selection of the method of risk assessment are oriented at carrying out this task. SWOT analysis as a traditional tool for an assess-ment of organization context (environment) influence is included into the list of risk management methods recommended by the international ISO 31000 stan-dards. However the traditional technique of carrying out SWOT analysis has shortcomings as well, in par-ticular, there are practically no ways of formalization at the selection assessment of the strategy and QMS development that complicates, increases the labor input of their realization and reduces the objectivity of obtained data. The solution of this problem is possible on the basis of the application procedure of statistical SWOT analysis justification in a quality management system of the organization allowing to increase reliabil-ity of the obtained data as a result of a research and to identify perspective for functioning and QMS strategy development correctly. In the article the procedure of statistical SWOT analysis justification of the results on the example of personnel selection in a quality man-agement system of the organization is considered.
INCREASE OF ORDERS COMPETITIVENESS AT THE INDUSTRIAL ENTERPRISE
Authors: Сорокина Елена , Sorokina Elena
Published: May 2017

Competition growth, increase of requirements to production quality and services on the part of custom-ers and, being a consequence of it, growth of uncertain-ty in many markets force the increasing number of machine-building enterprises to focus their production and economic structure and a control system on work by consumer order.

The article formulates the main approaches to management of production systems. Actions for in-creasing competitiveness of enterprise orders on the basis of internal potential are worked out. The structure of transformational production is considered. Reserves of increasing technical and economic efficiency for the purpose of competitive orders portfolio formation are revealed.
EFFICIENCY INCREASE OF USING INDUSTRIAL RESOURCES: MAIN ASPECTS
Authors: Стрижакова Екатерина , Strizhakova Ekaterina
Published: May 2017

Economists are interested in problems of increas-ing the efficiency of resource use in industry for a long time. However in modern conditions at the stage of the transfer to innovative way of development in the situa-tion of sanctions it is one of the key problems. In the article the author's principles of industrial systems management are formulated: compliance; systemacity and integrity; safety; coordination. The author's principle is marked out: the principle of alloca-tive according to which it is necessary to accept admin-istrative efforts for maximum effectiveness resources use and the measures applied in management process have to consider heterogeneous nature of the industrial system, and, therefore, in various sectors they have to be various. The author shows a formula for the growth rate of allocation system effectiveness, classification of re-sources and factors is carried out, the directions for the choice of extensive and intensive type of industrial system growth are shown. Special attention is paid to the management of intangible assets. Methods of in-creasing the efficiency of their use at the microlevel (the industrial enterprise) and macrolevel (industrial system of the country) of management are considered. Using the recommendations presented in the article will give the chance to increase allocative efficiency of the used resources, adaptive efficiency of the industrial enterprises that finally will lead to growth of the overall system effectiveness.
INTEGRATED APPROACHES TO ASSESSMENT OF STRATEGIC MANAGEMENT EFFICIENCY
Authors: Бойко Надежда , Boyko Nadezhda
Published: May 2017

The article specifies the need for reorganization of the existing control concepts towards the strategic orientation.

The essence of strategic control is formalized, and the difficulties arising at the Russian enterprises fol-lowing such restructuring.

The necessity to develop a complex scorecard is justified It allows, on the one hand, to transfer the strategy to operational terms, and on the other hand to provide a possibility of back coupling and complex monitoring of implementation of this strategy.

The analysis of various modern concepts of strategic management is carried out, it has shown advantages of the balanced scorecard concept which allows to present the strategy of the enterprise in a system of clearly formulated goals and tasks, and also the indicators providing feedback and defining the achievement level of strategic goals in terms of following aspects: finance; marketing; internal business processes; per

sonnel, training and growth.

Criteria for the indicators selection characterizing each projection of the system are considered. The ob-servance of the principles testifies to systemacity of approach and interrelation of the selected indicators.

The algorithm of a complex system creation for an assessment of strategic management efficiency using key components of Balanced Scorecard (BSC)-model on the basis of the financial analysis of the company is offered.

The key indicators of the assessment system of strategic management efficiency are presented. They are selected according to the given algorithm.

Advantages of the complex system for an assess-ment of strategic management efficiency are defined; expediency of its application at Russian enterprises is proved.
French Identity in Dynamics of Culture Philosophical and Lingvocultural Conception
Authors: Крылова  , Krylova S.
Published: May 2017

The author has made an overview of scientific publications and Russian developments dedicated to the study of specific ethno-cultural, regional, and national identity. Main content of the article aims to identify the positive promises of the theory of French identity in particular, developed in the works of the French researchers F. Braudel, P. Nora, etc. showing how changes in the cultural policies of French government affect French society. Results of the analysis of comments on the websites of French online media are also introduced, with the focus on social and cultural codes of French identity.
Social Roles in the Context of Critical Review and Their Linguistic Realization
Authors: Кремер  , Kremer Inessa
Published: May 2017

The paper deals with the analysis of social roles and their linguistic realization in German critical review. The paper presents theoretical grounds of the role of personality in the process of text production and gives historical background of this problem. The author of the paper characterizes social roles of participants of academic communication and shows peculiarities of interpersonal interaction. The paper presents linguistic markers of relations “reviewer — author review — reader”. The paper focuses on systematization of the basic language means.
Wastewaters Pollution Control Using Two-Frequency Laser Sounding
Authors: Алексеев  , Alekseev V. , Усольцев  , Usol'cev V. , Юран  , Yuran S.
Published: May 2017

Optical methods for analysis of non-uniform liquid mediums have been considered, correlational and functional connections between the optical density and parameters characterizing industrial wastewaters’ type, content and pollution level have been investigated. Have been demonstrated main tendencies related to development of technology and equipment for optoelectronic control of industrial wastewaters’ pollution. Approximation of emission and absorption spectra for optical radiation’s emitter and receiver using the known Laplace function allows carry out calculations for a choice of optical couples’ coordinated parameters for two-frequency optical control, and as a result to increase reliability of identification for a type and degree of pollution for wastewaters and industrial effluents in comparison with use of one emission source. The method of pollution two-frequency laser sounding differs in improved control characteristics compared with the ones offered in patents, as well as in scientific and technical literature.