bluuebunny/crossref_metadata_2025 huggingface dataset:
When the heart deceives: a case report of hyperthyroidism disguised as STEMI in female pregnant patient
Authors: Wibawa Kevin , Wiyono Lidia Debby , Dewangga Raditya , Sumarna Arief , Syamsuri Wizhar , Ariffudin Yandi , Suhendiwijaya Suhendiwijaya , Syah Pangeran Akbar
Published: January 2025

Background

Acute myocardial infarction during pregnancy is a rare condition with an incidence of 1 to 10 per 100,000 deliveries. ST-elevation myocardial infarction (STEMI) is dominating the clinical presentation. It is estimated that 29% of the patients had normal coronary arteries, and hyperthyroidism may be associated with coronary vasospasm.

Case Presentation: A 30-year-old pregnant woman was referred with inferior STEMI post-failed fibrinolytic therapy. Her hospitalization course was complicated by non-sustained ventricular tachycardia and cardiogenic shock. Coronary angiography revealed normal coronary arteries without intracoronary thrombus, coronary dissection, or coronary atherosclerotic lesion. Laboratory test showed high Free T4 2.71 ng/dL and low TSH < 0.05 mlU/mL. Patient’s condition and hospitalization course were significantly improved after the initiation of hyperthyroid therapy. We suspected a hyperthyroid-induced coronary vasospasm as a potential etiology of myocardial infarction with non-obstructive coronary artery (MINOCA) in this patient.

Conclusion

Although MINOCA due to hyperthyroidism is a rare finding among pregnant young woman, recognizing this etiology is a paramount of importance due to improved survival with appropriate and specific therapy.
Anthropomorphism in artificial intelligence: a game-changer for brand marketing
Authors: Gomes Sofia , Lopes João M. , Nogueira Elisabete
Published: January 2025

The expansion of brands adopting artificial intelligence services with human characteristics, such as chatbots, has revolutionized digital marketing strategies, transforming how companies reach and engage customers. This technological innovation is reshaping digital interactions between companies and consumers, offering a more personalized and efficient experience. This study explores the influence of chatbot anthropomorphism on customer engagement and purchasing decision-making with brands that use this artificial intelligence service. Data from a questionnaire with 1319 participants was analyzed using partial least squares method. Chatbot anthropomorphism has a more positive influence on purchasing decision-making when this relationship is mediated by customer engagement. In turn, customer involvement also has a positive influence on decision-making. The results emphasize that for a greater influence of the chatbot's anthropomorphism on purchasing decision-making, the customer must first be engaged with the chatbot. This research illuminates a new path in the domain of AI-enabled brand interactions, showing the distinct influence of anthropomorphism in chatbots on customer satisfaction, trust and loyalty, thus revolutionizing traditional paradigms of consumer-brand engagement and decision-making processes. By exploring the intricate dynamics between customer engagement with anthropomorphized chatbots and purchasing decisions, this study breaks new ground, offering unprecedented insight into the transformative potential of human-like chatbot interactions in shaping consumer behavior and brand relationships.
Intralesional steroid injection in keloid ear — a prospective observational study
Authors: Bangalore Narayanaswamy Vinod , H Tejaswini , H M Saritha , H N Udayabhanu , H K Nagarathna
Published: January 2025

Background

Keloid is a fibro-proliferative dermal benign growth affecting the Asian population. In India, ear keloids are common, often resulting from ear piercing, a prevalent cultural practice. The resultant ear keloids pose aesthetic concerns, leading to significant psychological distress, and necessitating effective treatment. While various treatment options are available, their outcomes and recurrence rates vary, highlighting the need for individualized and optimal management strategies. Our study aimed to observe the combined effect of intralesional triamcinolone with hyaluronidase on keloid regression.

Methods

This prospective observational study was conducted at our tertiary care institute over 1 and a half years. Fifty patients who met the inclusion criteria were enrolled and received intralesional triamcinolone injection with hyaluronidase. Keloid regression was assessed using the Vancouver Scar Scale (VSS), while the visual analogue score (VAS) and patient satisfaction score (PSS) provided subjective evaluations of symptom relief. All patients underwent compression therapy. Patients were evaluated at every visit and then at 1 year for symptom relief, keloid regression, and complications if any.

Results

Demographic data of all patients were recorded. Ear keloids were predominantly observed in females, with a male-to-female ratio of 18:32. The most common etiology was trauma following ear piercing, accounting for 46% of cases. All patients showed improvement in VSS, VAS, and PSS scores in the follow-up visits. A total of 98% of patients demonstrated a complete treatment response, with only a single instance of recurrence.

Conclusion

Intralesional triamcinolone with hyaluronidase provides satisfactory symptomatic relief and has lower recurrence rates. All patients showed improvement in the Vancouver Scar Scale and had enhanced VAS and PSS scores.
Coupling Fully Staggered Grids via Numerical Filtering for Wave Propagation Simulation
Authors: Jiang Luqian , Tian Jun , Lei Tao , Zhang Wei
Published: January 2025

The fully staggered grid (FSG) combines multiple standard staggered grids (SSGs) to simulate seismic wave propagation in anisotropic elastic media. However, its accuracy is contingent upon the wavefield’s consistency and continuity across multiple sets of SSGs. In isotropic or weakly anisotropic media, decoupling or weak coupling between the SSGs can lead to wavefield discontinuities at adjacent grid points in the diagonal direction. Issues such as inconsistent source activation, medium parameter discontinuities, and different numerical treatments of boundary conditions over multiple sets of SSGs can exacerbate these problems. While previous methods, such as FD-consistent point source technique and equivalent medium parameterization methods, have partially addressed these issues, they do not completely solve the problem. This study, drawing inspiration from numerical damping techniques used in collocated-grid finite-difference schemes to eliminate odd-even oscillations, introduces an explicit filter operator along the diagonal direction of the FSG. This approach ensures wavefield consistency and continuity across multiple SSGs, improving the accuracy of the FSG scheme. Although this method increases computational costs, it is essential for reliable seismic modeling in anisotropic media.
Reimagining psychosis prevention: responding to the accessibility issues of At-Risk Mental State (ARMS) services through a selective public health approach
Authors: Brown Luke , Griffiths Siân Lowri
Published: January 2025

At-Risk Mental State (ARMS) services aim to prevent the onset of first-episode psychosis (FEP) in those with specific clinical or genetic risk markers. In England, ARMS services are currently expanding, but the accessibility of this preventative approach remains questionable, especially for a subgroup of FEP patients and those from specific ethnic minority communities. This commentary outlines the key debates about why a complimentary approach to psychosis prevention is necessary, and gives details for an innovative public health strategy, drawing on existing research and health prevention theory.
The history of biomarkers in psychiatry: lessons learned, lessons forgotten, lessons rediscovered
Authors: Berk Michael , Forbes Malcolm , Narayanaswamy Janardhanan
Published: January 2025

A quirky truth is that the oldest biomarker findings are largely metabolic. These had minimal impact on contemporary thought and research and were largely ignored. They have been rediscovered and validated almost 100 years later, informing our understanding of neurobiology and medical comorbidity and spurring contemporary treatment discovery efforts.
Inter-event time power laws in heterogeneous systems
Authors: Ettori F. , Sluckin T. J. , Biscari P.
Published: January 2025

We investigate the dynamic behavior of spin reversal events in the dilute Ising model, focusing on the influence of static disorder introduced by pinned spins. Our Monte Carlo simulations reveal that in a homogeneous, defect-free system, the inter-event time (IET) between local spin flips follows an exponential distribution, characteristic of Poissonian processes. However, in heterogeneous systems where defects are present, we observe a significant departure from this behavior. At high temperatures, the IET exhibits a power-law distribution resulting from the interplay of spins located in varying potential environments, where defect density influences reversal probabilities. At low temperatures, all site classes converge to a unique power-law distribution, regardless of their potential, leading to distinct critical exponents for the high- and low-temperature regimes. This transition from exponential to power-law behavior underscores the critical response features of magnetic systems with defects, suggesting analogies to glassy dynamics. Our findings highlight the complex mechanisms governing spin dynamics in disordered systems, with implications for understanding the universal aspects of relaxation in glassy materials.
Changes in 90-Day Time in Range Among Youth With Type 1 Diabetes Initiating Different Automated Insulin Delivery Systems
Authors: Gera Sonia , Rearson Andrew , Baker Greyson , Douvas Julia L , Alicea-Trelles Nicole , Gallop Robert J , Meighan Seema , Marks Brynn E
Published: January 2025

Context

Glycemic outcomes in youth with type 1 diabetes (T1D) in the United States using the 2 most common automated insulin delivery (AID) systems, Insulet Omnipod 5 (OP5) and Tandem Control IQ (CIQ), have not been compared.

Objective

We performed the first head-to-head analysis of changes in glycemic metrics among youth initiating AID.

Methods

This single-center, retrospective study included youth < 21 years with T1D, who started OP5 or CIQ between January 2020 and December 2023, and had ≥ 70% continuous glucose monitoring (CGM) active time. We obtained 14-day baseline and 90-day CGM and AID data. A multiple linear regression model assessed for changes in 90-day time in range (TIR) according to AID system, adjusting for covariates. Subanalyses were conducted according to baseline TIR categories.

Results

Among the 428 included youth, there were 214 (50%) in each AID group. OP5 users had a shorter T1D duration (1.6 vs 5.5 years, P < .001) and were more likely to have transitioned from multiple daily injections (76.1% vs 20.1%, P < .001). Baseline TIR was similar between groups (OP5 51.6% vs CIQ 53.1%, P = .70). 90-day TIR increased in both groups (P < .001), rising by 11.8 percentage points (95% CI [10.4, 13.3]) in OP5 users and 9.8 percentage points (95% CI [8.3, 11.2]) in CIQ users, without any significant between-group differences (P = .08). There were no between-group differences in 90-day TIR according to categorical baseline TIR.

Conclusion

There are no clinically significant differences in 90-day TIR among youth with T1D initiating the 2 most commonly used AID systems. Patient preference and shared decision making should continue to guide the selection of AID systems.
Pros and Cons of Inpatient SGLT2i Use for Hyperglycemia and Heart Failure
Authors: Fried Hayley , Harris Yael Tobi , Schulman-Rosenbaum Rifka
Published: January 2025

Sodium-glucose cotransporter 2 inhibitors (SGLT2is), originally approved by the US Food and Drug Administration for glycemic control in type 2 diabetes mellitus (DM2), have shown substantial cardiovascular and renal benefits, leading to their expanded use in managing heart failure (HF) and chronic kidney disease in the outpatient setting. Despite these benefits, their use for inpatient hyperglycemia management is not universally endorsed due to safety concerns and inadequate data. However, emerging evidence suggests potential advantages of initiating SGLT2i treatment for patients during hospitalization in the setting of HF. While SGLT2is are not recommended for managing inpatient hyperglycemia, initiation during hospitalization for HF provides significant benefits. We review the current literature on the pros and cons of using SGLT2is in hospitalized DM2 and HF patients and provide guidance on careful patient selection and risk mitigation for inpatient use.
Horace Walpole, the Prince, and the Baron
Authors: Guthrie Neil
Published: January 2025

The precise nature of Horace Walpole's sexuality remains elusive, in spite of the extent of his surviving correspondence — which is vast but with notable and possibly strategic gaps. Walpole's reactions to two queer men he encountered in Italy, Cardinal Prince Henry Benedict and Baron Philipp von Stosch, nevertheless reveal some of his preoccupations and anxieties in relation to male-male sexual desire.
The Dynamics of Authorial Forgetting: The Case of James Robertson
Authors: Walker Robert G.
Published: January 2025

James Robertson (1713 – 95) was born in Dublin but spent most of his life in England. By profession a comic actor associated for two decades with the York Theatre, in 1770 he published anonymously a relatively large volume of poetry (239 pages), with the title Poems, Consisting of Tales, Fables, Epigrams, &c. &c. By Nobody. His attribution of his poetry to Nobody was playful, but, in an irony of history, it has turned out to be prophetic. Despite the relative success of this volume — it went through three additional editions in his lifetime — and despite a surprising amount of contemporary recognition both as a player and as a poet, he has now totally disappeared from literary history. I suggest how and why he lost his place in the canon and what value there is in reading his work today, especially as a signpost of the relative persistence of Augustan satire (Pope, Swift, and others) beyond the death of Pope in 1744.
The genome sequence of the Ruddy Darter, Sympetrum sanguineum (Müller, 1764)
Authors: Crowley Liam M. , Wawman Denise C. ,   University of Oxford and Wytham Woods Genome Acquisition Lab,   Darwin Tree of Life Barcoding collective,   Wellcome Sanger Institute Tree of Life Management, Samples and Laboratory team,   Wellcome Sanger Institute Scientific Operations: Sequencing Operations,   Wellcome Sanger Institute Tree of Life Core Informatics team,   Tree of Life Core Informatics collective,   Darwin Tree of Life Consortium
Published: January 2025

We present a genome assembly from a male specimen of Sympetrum sanguineum (Ruddy Darter; Arthropoda; Insecta; Odonata; Libellulidae). The haplotype-resolved assembly contains two haplotypes with total lengths of 1,500.53 megabases and 1,304.05 megabases. Most of haplotype 1 is scaffolded into 13 chromosomal pseudomolecules, including the X sex chromosome, while haplotype 2 is scaffolded into 12 autosomes.
Taxes and taxation
Authors: Sidorova Elena , Boboshko Diana
Published: January 2025

The textbook contains theoretical and practical material on the sections "General provisions of the functioning of the tax system in the Russian Federation" and "Tax administration in the Russian Federation". The material is presented logically, which will allow students to consistently master lectures on the discipline "Taxes and Taxation" and consolidate their knowledge on practical examples given in the text.
Meets the requirements of the latest generation of federal state educational standards for higher education.
For students studying in the enlarged group of specialties 38.03.00 "Economics and management".
Archivo (audio/visual) y memoria del colonialismo en Latinoamérica: Buscando a “Isla de Pascua”. La película perdida (2014) y Apenas el sol (2020).
Authors: Genschow Karen
Published: January 2025

Los documentales Buscando a “Isla de Pascua”. La película perdida (Chile, 2014)
y Apenas el sol (Paraguay, 2020) abordan historias coloniales situadas en el siglo
XX en dos regiones en la periferia latinoamericana, legibles ambas en términos
de colonialismo interno. Las respectivas historias se (re)construyen mediante el
recurso a archivos audio/visuales –precarios y frágiles–, producidos en un caso previamente, en el otro simultáneamente con la producción del documental. El artículo
analiza el uso del archivo que técnicamente aparece como remediación y políticamente
se revela como parte de un proyecto de descolonización.
Adjacency spectrum and Wiener index of essential ideal graph of a finite commutative ring
Authors: Jamsheena Panikkara , Chithra Velu , Subarsha Banerjee
Published: January 2025

Let R be a commutative ring with unity. The essential ideal graph ER of R, is a graph with a vertex set consisting of all nonzero proper ideals of R and two vertices I and K are adjacent if and only if I + K is an essential ideal. In this paper, we study the adjacency spectrum of the essential ideal graph of the finite commutative ring Zn, for n = {pm, pm1qm2}, where p, q are distinct primes, and m, m1 , m2 ε N.  We show that 0 is an eigenvalue of the adjacency matrix of EZn if and only if either n = p2 or n is not a product of distinct primes. We also determine all the eigenvalues of the adjacency matrix of EZn whenever n is a product of three or four distinct primes. Moreover, we calculate the topological indices, namely the Wiener index and hyper-Wiener index of the essential ideal graph of Zn, for different forms of n.
How Would Alfred Adler View America’s Loneliness Epidemic? Reflections by His Biographer
Authors: Hoffman Edward
Published: January 2025

ABSTRACT: U.S. Surgeon General Vivek Murthy (2023) has declared that America is experiencing an “epidemic” and “health-care crisis” related to loneliness. Although Alfred Adler is not alive to respond to this dismaying situation, his life and writings offer a vital direction for understanding the nature of this epidemic and reacting appropriately. As Adler’s biographer, I focus on four relevant causal factors concerning chronic loneliness among adolescents and young adults today: intrapsychic, familial, pedagogic, and wider societal forces. Relevant interventions are then discussed.
Modeling of chemo-radiotherapy targeting growing vascular tumors: A continuum-level approach
Authors: Lampropoulos Ioannis , Koutsi Marina , Kavousanakis Michail E.
Published: January 2025

The aim of this study is to demonstrate the enhanced efficiency of combined therapeutic strategies for the treatment of growing tumors, based on computational experiments of a continuous-level modeling framework. In particular, the tumor growth is simulated within a host tissue and treated as a multiphase fluid, with each cellular species considered as a distinct fluid phase. Our model integrates the impact of chemical species on tumor dynamics, and we model –through reaction-diffusion equations– the spatio-temporal evolution of oxygen, vascular endothelial growth factor (VEGF) and chemotherapeutic agents. Simulations of a growing tumor exposed to external radiation showcase the rapid impact of radiotherapy on tumor suppression, however this effect diminishes over time. To enhance the therapeutic efficiency of radiotherapy, we investigate the combination of external radiation with the anti-VEGF drug bevacizumab and the cytotoxic drug docetaxel. Our simulations demonstrate that this synergistic approach integrates the immediate effectiveness of radiation therapy with the enduring tumor-suppressive capabilities of chemotherapy.
Relationship between nocturnal blood pressure dip and β-parapapillary atrophy zone choroidal vessel density in normal-tension glaucoma patients
Authors: Park Jimin , Song Woo Keun , Baek Min Su , Yoon Jooyoung , Lee Anna , Kim Ko Eun , Kook Michael S.
Published: January 2025

Purpose

To investigate the relationship between nocturnal blood pressure (BP) dip and parapapillary choroidal vessel density (pCVD) in patients with normal-tension glaucoma (NTG)

Methods

This study analyzed 267 eyes of 267 untreated NTG patients who underwent 24-hour (h) intraocular pressure (IOP) and ambulatory BP monitoring in the habitual position. Patients were classified into 3 groups [non-dippers (nocturnal BP dip < 10%), dippers (nocturnal BP dip between 10% and 20%, and over-dippers (nocturnal BP dip > 20%)], and pCVDs were measured by using optical coherence tomography angiography (OCTA) images. Logistic regression analyses were performed to identify clinical factors associated with “over-dipper” cases. Linear regression analyses were conducted to determine the correlation between various clinical variables and pCVD.

Results

In clinical characteristics, over-dippers exhibited lower pCVD values compared to non-dippers or dippers (P = 0.004). High diurnal intraocular pressure (IOP) fluctuation (P = 0.031), high diurnal mean arterial pressure (MAP) fluctuation (P = 0.001), and low pCVD (P = 0.002) were identified as predictors of being “over-dipper” in multivariable logistic regression analyses. Moreover, peripapillary retinal vessel density (P = 0.040), presence of choroidal microvasculature dropout (P = 0.039), and nocturnal MAP dip % (P = 0.002) showed significant correlations with pCVD according to multivariable linear regression analyses.

Conclusion

Over-dippers presented with lower pCVD than non-dippers or dippers as measured by OCTA choroidal images. Low pCVD was a predictor of “over-dipper” cases and associated with a greater percentage of nocturnal MAP dip in NTG patients. 24-h ambulatory BP monitoring may provide further information for detecting low pCVD in NTG patients with nocturnal BP dip.
Biografia e identidade no Império Romano
Authors: Brandão José Luís , Teixeira Cláudia , Faversani Fábio , Rodrigues Ália Rosa C.
Published: January 2025

O presente volume inclui estudos teóricos sobre a Biografia, suas origens e desenvolvimentos na Grécia e em Roma, bem como a sua relação com a História Antiga, convergindo no tratamento biográfico do regime imperial romano dos séculos I a.C. a II d.C. Além da referência a diversos biógrafos, são objeto especial de análise biografias de Josefo, Plutarco, Suetónio, Quinto Cúrcio, Tácito e História Augusta e Vidas de governantes — Alexandre, Augusto, Tibério, Galba, Otão, Adriano e Cómodo —  e de políticos influentes, como Gemânico e Agrícola.
Etika, közgazdaságtan és verseny: Néhány tanulság az amerikai intézményi gazdaságtanból
Authors: Csontos Tamás
Published: January 2025

Az utóbbi évtizedekben domináns neoliberális közgazdasági gondolkodás a közgazdaság-
tant értéksemleges tudományként ábrázolta, amely csak korlátozott teret enged az érté-
kekről szóló vitáknak. Az etikus gazdaságtani kutatások újbóli előtérbe kerülésével viszont
ismét felmerült a kérdés: szükséges-e a közgazdászoknak etikával foglalkozniuk szakmájuk
helyes műveléséhez? Tanulmányunk az amerikai intézményi közgazdaságtani hagyomány
alapján vizsgálja, hogy az etikai kérdések beemelése hogyan gazdagíthatja a közgazdaság-
tant. Három jelentős amerikai intézményi közgazdász, Richard T. Ely, Simon N. Patten és
Frank H. Knight, munkáit elemezzük, akik kiemelkedő szerepet játszottak az etika és a köz-
gazdaságtan közötti kapcsolat erősítésében. Műveik alapján amellett érvelünk, hogy az eti-
kai kérdések nemcsak relevánsak, hanem nélkülözhetetlenek a közgazdaságtani gyakorlat
javítása szempontjából. Tanulmányunk rávilágít arra, hogy egy megalapozottabb közgaz-
daságtani elmélet kialakításához szükséges a normatív és a leíró megközelítés harmóniája,
valamint az értéktartalom felismerése a gazdasági fogalmak mögött. A vizsgált munkák azt
is hangsúlyozzák, hogy a gazdasági fejlődést a morális fejlődéssel összhangban érdemes
szemlélnünk.
Ki kezelje a kasszakulcsot? A kisvállalati szektor tulajdonosainak gazdasági ismerethiánya termeli újra a tartós versenyképességi hátrányt
Authors: Bodonyi Andrea
Published: January 2025

A kis- és középvállalkozások számára elengedhetetlen egy olyan átfogó gazdasági szem-
lélet, amely egyaránt figyelembe veszi a mikro- és makrogazdasági tényezőket. Az üzleti
kultúra és a vállalatvezetők gazdasági képzettségének hiánya gyakran korlátozza a vállal-
kozások lehetőségeit, különösen az optimális finanszírozási forma megválasztásában a tá-
mogatások elnyerésében és a rendelkezésre álló erőforrások stratégiai felhasználásában.
Kutatásom célja, hogy bemutassa, hogyan járulhat hozzá a gazdasági szempontok tudatos
integrálása a kis- és középvállalkozások fenntartható versenyelőnyének megteremtéséhez,
és ezáltal a szektor egészének növekedéséhez. A tanulmány több nézőpontból vizsgálja a
gazdasági szemlélet jelentőségét a vállalatvezetésben, és arra a következtetésre jut, hogy
a pénzügyi szaktudás integrálása kulcsfontosságú a hosszú távú siker érdekében. Ez meg-
valósítható belső erőforrásokkal, tanácsadással vagy továbbképzéssel is. Összességében a
pénzügyi szaktudás formája kevésbé lényeges, a legfontosabb annak hatékony és szakértői
kezelése, amelyhez a megfelelő támogatást biztosítani kell a vállalatok számára.
Nils Bruch, Michèle Knodt, Marc Ringel: A keményebb puha kormányzás szorgalmazása az Európai Zöld Megállapodásért: Az érintettek nézőpontjai az EU kormányzási rendeletének felülvizsgálatáról4
Authors: Auguszt Anna Apollónia
Published: January 2025

A cikk szerzői és célja
A cikk szerzői Nils Bruch és Michèle Knodt a Darmstadti Műszaki Egyetemről, valamint
Marc Ringel, aki a ludwigsburgi Német-Francia Intézetnél dolgozik és emellett a párizsi
Sciences Po-nál, ahol a Fenntartható Fejlődés és Klímaátmenet Európai Tanszék kutatója.
A tanulmány az Európai Parlament és a Tanács rendeletével (Regulation (EU) 2018/1999)
foglalkozik. A 2018-ban elfogadott, az EU energiával és klímavédelemmel kapcsolatos célki-
tűzéseinek elérését szolgáló központi irányítási eszköz. A rendelet felülvizsgálata esedékes,
mert a végrehajtás és az új uniós keretrendszerhez való illeszkedés terén hiányosságo-
kat mutat. Az Európai Zöld Megállapodás (European Green Deal), a Fit-for-55 csomag és
a REPowerEU terv (melyet az orosz-ukrán háború nyomán vezettek be) szigorúbb célokat
tűztek ki, amelyek felfedték a rendelet gyengeségeit a végrehajtási mechanizmusok terén.
A tanulmány célja megvizsgálni, hogy a rendelet miként integrálhatja a keményebb „puha
kormányzás” (soft governance) elemeit ezeknek a hiányosságoknak a kiküszöbölésére.
Daniel Goodwin, Fred Gale, Heather Lovell, Kim Beasy, Hannah Murphy, Marion Schoen: Fenntarthatósági tanúsítvány a megújuló hidrogénért: Nemzetközi felmérés energetikai szakemberek körében5
Authors: Piricz Mihály
Published: January 2025

Az elmúlt években a megújuló hidrogén a globális energiapolitikában rendkívül fontos té-
mává vált, mivel kulcsfontosságú szerepet játszhat a dekarbonizációs célok elérésében.
Daniel Goodwin és szerzőtársai (School of Social Sciences -, School of Geography, Planning,
and Spatial Sciences - and School of Education, University of Tasmania) arra vállalkoznak,
hogy feltárják a megújuló hidrogén fenntarthatósági tanúsítási rendszereinek jelenlegi álla-
potát, és értékeljék azok szerepét a fenntarthatósági célok elérésében. A szerzők nemzet-
közi felmérést végeztek energiaipari szakemberek körében, hogy jobban megértsék, mely
fenntarthatósági jellemzők fontosak a hidrogén tanúsítási rendszerekben, és hogy ezek
milyen kockázattal járhatnak.
Democracy that Delivers #408 – FEDN Global Conference – Democratic Challenges and Opportunities in Asia
Authors: Phayvanh Inthanon
Published: January 2025

According to the podcast article of Democracy that Delivers “FEDN Global Conference –
Democratic Challenges and Opportunities in Asia” (2024) [1], both host and guests from
the Center for International Private Enterprise were deeply discussing the chances and
challenges that Asian regions will face.
Németország szerepvállalása Latin-Amerika társadalmi fejlődésében
Authors: Fernandez Saralegui Clara
Published: January 2025

Németország döntő fontosságúnak tartja Latin-Amerikával való együttműködését.
Biocompatibility of electrospun PVA-based nanocomposite with chemical vapor deposition-derived graphene monolayer
Authors: Sasmazel Hilal Turkoglu , Alazzawi Marwa , Sadhu Verra , Gozutok Melike
Published: January 2025

The biocompatibility of electrospun PVA with monolayer graphene obtained by chemical vapor deposition (PVA/CVD-grown MLG) nanocomposite was investigated. The properties of PVA/CVD-grown MLG nanocomposite were compared with those of electrospun PVA mat. Raman analysis confirmed the presence of graphene monolayer on PVA. Although no significant changes in tensile properties were observed, the electrical conductivity increased from 0.1 (PVA mat) to 0.4 μS/cm (PVA/CVD-grown MLG). Thermal stability was also increased, as evidenced by the higher onset temperature and temperature of maximum decomposition rate determined by TGA. The contact angle decreased slightly, which resulted in higher PBS absorption and degradation of the nanocomposite. Water vapor transmission rate (WVTR) decreased from 40 (PVA mat) to 37 g/m2 h (PVA/CVD-grown MLG). Cell culture studies showed better cell viability, population, and growth in the case of PVA/CVD-grown MLG nanocomposite due to improved physical, chemical and mechanical properties.
Postprandial glycemic response to isocaloric carbohydrate load in men with different types of obesity
Authors: Pinkhasov B. B. , Sorokin M. Yu. , Selyatitskaya V. G.
Published: January 2025

BACKGROUND: Carbohydrates exert major impact on postprandial blood glucose levels. Diet therapy for obesity and diabetes mellitus usually implies dietary restrictions on the amount, type and daily distribution of carbohydrates, wherein the timing of meals and its composition play a significant role. However currently there is insufficient evidence-based data to guide how carbohydrates consumption should be distributed during a day in obese men.AIM: To investigate postprandial glucose levels in response to an isocaloric carbohydrate load at main meals (breakfast, lunch, dinner) in individuals with different types of obesity.MATERIALS AND METHODS: The study enrolled men aged 25 to 65 years. The total number of study participants was 43 men. Group 1 (n=17) consisted of obese men with subcutaneous type of fat distribution (SFD) while group 2 (n=16) was represented by obese men with abdominal type of fat distribution (AFD). Group 3 (comparators) consisted of 10 men with normal body weight (NBW). The duration of continuous glucose monitoring was 5–6 days. Observation period included 3 days of usual physical and work activity regimens. Glycemic response on carbohydrate isocaloric load was assessed on different days and mealtime. During first and fifth days men were instructed to eat as usual without any restrictions. Standard carbohydrate breakfast was introduced during the second day while standard carbohydrate lunch and dinner were performed at the third and fourth days respectively.RESULTS: Results of isocaloric carbohydrate load representing different standard meals (breakfast, lunch, dinner) showed that in NBW men the most intense utilization of glucose occurs in the morning during breakfast. Glucose tolerance was significantly lower at all meals in AFD men group comparing to men with NBW and SFD. In men with SFD glucose tolerance was relatively lower than in NBW men only during standard breakfast. At lunch and dinner time disposition of the glycemic curve in men with SFD and NBW didn’t significantly differ.CONCLUSION: Dividing men according to obesity phenotypes allows to identify features of regulation of carbohydrate metabolism and as a result to reveal different risk levels of type 2 diabetes and its’ complications. The combination of continuous glucose monitoring with dietary control can significantly increase the effectiveness of therapeutic interventions for obesity and offers a pathogenetic approach to personalized diet therapy
Insufficient attention to the problem of obesity using the example of low inclusion in TMC with a specialized scientific center.
Authors: Komshilova K. A. , Mazurina N. V. , Ershova E. V. , Sazonova D. V. , Vikulova O. K. , Gasymova I. R. K. , Nazarova A. S. , Troshina E. A.
Published: January 2025

Obesity is a complex multifactorial pathology associated with a complex of metabolic, cellular, cardiovascular factors leading to extremely negative health consequences, which determines the high social significance of this nosology. Telemedicine technologies are being widely implemented in practical healthcare, including can be used for many obese patients. Currently, the true prevalence of obesity is not reflected in the forms of statistical registration of diseases and, often, is not considered by doctors as the main cause of the development of cardiovascular diseases, carbohydrate metabolism disorders and diseases of the musculoskeletal system. The underestimation of the problem of obesity is also reflected in the structure of telemedicine consultations with a specialized endocrinological research center
Experience of surgical treatment of morbid obesity in a patient with hypercortisolism and primary hyperparathyroidism: prioritization
Authors: Komshilova K. A. , Cheredanova V. R. , Ershova E. V. , Mazurina N. V. , Platonova N. M. , Beltsevich D. G. , Yukina M. Yu. , Troshina E. A.
Published: January 2025

Morbid obesity is a pathology associated with a complex of metabolic disorders, type 2 diabetes mellitus, and cardiovascular diseases, leading to extremely negative health consequences, which necessitates a multidisciplinary approach. The presented clinical case is an example of a combination of primary (exogenous-constitutional) obesity with two other endocrine diseases, and it demonstrates the importance of determining the optimal treatment tactic for a patient with morbid obesity, taking into account his concomitant diseases. Step-by-step patient treatment was carried out by a team of therapeutic and surgical specialists
Innovative approaches to the treatment of obesity: from pharmacotherapy to nanomedicine
Authors: Romantsova T. I.
Published: January 2025

Currently, 879 million adults in the world are obese. Obesity and type 2 diabetes have common key pathophysiological mechanisms. Weight loss is an integral part of diabetes management. Advances in the study of the pathogenesis of obesity contribute to the development and introduction into clinical practice of innovative technologies to combat the epidemic of obesity and diabetes mellitus. New drugs take effect at the level of the central nervous system, gastrointestinal tract, adipose tissue, kidneys, liver, pancreas, and skeletal muscles. The safety of gene therapy is being evaluated, and the potential of special methods of drug delivery to target tissues is being studied. Randomized clinical studies show that the effectiveness of a number of new pharmacological drugs in weight loss and carbohydrate metabolism normalization is already almost comparable to that of bariatric surgery. This review summarizes the literature on the prospects for the treatment of obesity and type 2 diabetes based on developments primarily in the field of peptide drugs, monoclonal antibodies, and RNA therapy.
Clinical guidelines «Obesity in children»
Authors: Vasyukova O. V. , Okorokov P. L. , Malievskiy O. A. , Neimark A. E. , Zorin E. A. , Yashkov Y. I. , Burmitskaya Yu. V. , Kopytina D. A. , Bezlepkina O. B. , Peterkova V. A.
Published: January 2025

Childhood obesity is an urgent problem of pediatric endocrinology due to the widespread occurrence, the development of metabolic complications and their steady tracking into adulthood. The developed clinical guidelines are the main working tool of the practitioner. They briefly and structurally present the main information about the epidemiology and modern classification of obesity, methods of its diagnosis and treatment based on the principles of evidence-based medicine.
A rare case of a combination of metabolic and genetic changes in one patient (multiple endocrine neoplasia type 1 syndrome and Williams syndrome)
Authors: Filkina E. E. , Przhiyalkovskaya E. G. , Lazareva A. A. , Yukina M. Yu.
Published: January 2025

Asthma and obesity are diseases characterized by variability in the course and possible complications, the frequency of which is steadily increasing from year to year. The correlation between obesity and asthma is still an acute problem of the health care system. Representing very common diseases, they aggravate each other’s course and significantly worsen the quality of life. Polyphenols are a promising option to solve the existing problem. These low molecular weight compounds are biologically active substances capable of influencing on many metabolic processes in the body. This review demonstrates the multiple properties of these unique micronutrients, including antioxidant, anti-carcinogenic, anti-inflammatory, metabolic, neuroprotective and many others. The integration of polyphenols into the daily diet can contribute to strengthening public health, reducing the frequency and progression of socially significant diseases, and using these compounds in diseases such as asthma and obesity, according to numerous modern studies, it is possible to achieve a significant therapeutic effect at all. The purpose of this literature review is to trace the correlation between the effect of using polyphenols and changes in the course of the disease and quality of life in patients with asthma on the background of obesity, based on facts from advanced sources
Radiofrequency echographic multi-spectrometry and prolactinoma: case report
Authors: Shutova A. S. , Dzeranova L. K. , Pigarova E. A. , Vorotnikova S. Yu. , Buyvalenko U. V. , Perepelova M. A. , Kuzmin A. G.
Published: January 2025

In case of prolactin-secreting pituitary adenomas, the attention of patients and physicians is drawn to the clinical manifestations of pituitary adenoma, including associated metabolic disorders. The success of conservative methods of treating prolactinomas, the development and implementation of new approaches to the treatment of aggressive and resistant pituitary adenomas allow us to focus on non-obvious pathological conditions accompanying prolactin-secreting adenomas. These include secondary bone metabolism disorders with decreased bone mineral density (BMD), leading to osteoporosis and low-traumatic fractures. The key to effective prevention and treatment of osteoporosis is timely and accurate diagnostics, but not all methods for determining BMD developed to date can be characterized in this way. This paper highlights the use of new methods for diagnosing osteoporosis in the context of its high risk in hormonally active pituitary adenomas, in particular in prolactinomas, using a real clinical case as an example
Influence of social media on children's dietary habits
Authors: Kadhim Ashour Qasim
Published: January 2025

Introduction: Dietary habits refer to the consistent choices made by individuals or groups concerning their food consumption. It has a crucial influence in human health and reflects individual eating choices, which are often associated with culture, education, social background, and health status. Dietary habits may be influenced and altered by life stages and lifestyle factors, including physical activity and social interac-tion. Nutritional consumption significantly influences human health and well-being, particularly during childhood and adolescence, and directly impacts children's health due to their physical, mental, and cognitive development. Approaches: Data has been gathered from 100 children to evaluate the impact of social media on their dietary practices. The questionnaire was administered to professionals to establish its validity and subsequently its reliability. The total number of items in the questionnaire was 19. To evaluate children's behavior on social media about eating practices. The data was gathered by a simple random sampling process and analyzed using both descriptive and inferen-tial statistical techniques. Outcomes The results indicated that among 100 children, the mean age of participation was 15.66 years. The cur-rent study demonstrated a moderate impact of social media on children's food habits. The study demonstrated a substantial statistical link between children's age and hours spent on social media, as well as the impact of social media on children's food habits (p < 0.05). The re-sults indicated no statistically significant differences (p > 0.05) between social media usage and other demographic variables. Concludes The findings indicated that social media exerted a moderate influence on children's food habits. The study concluded that a substantial statistical link exists between children's age, hours of social media usage, and the impact of social media on children's food habits. The results indicat-ed no significant statistical differences between social media usage and other demographic variables.
Caracterización de la identidad cultural para el turismo de Sincelejo (Colombia)
Authors: Méndez Prada Martha Cecilia , Cardona Arce Yolanda Patricia , León Santiesteban Dr. Martín , Guerrero Mosquera Nelly , Mercado Covo Tatiana Margarita
Published: January 2025

El propósito de este artículo es describir los atributos de la identidad cultural de Sincelejo. Se utilizó una metodología cuantitativa descriptiva, la cual incluyó una encuesta realizada a 211 participantes. Los resultados se analizaron mediante el software SPSS versión 26, con el apoyo de Excel 2023. La información recopilada da cuenta de los elementos que reconocen tanto residentes como visitantes y empresarios sobre lo que distingue a esta ciudad región para potenciar el turismo, que incluye Morroa, Corozal y Sampúes. Entre los atributos reconocidos de la gastronomía se encuentran, el mote de queso y el sancocho; en cuanto a la música y el baile, el porro, el fandango y el vallenato. La religión es predominantemente católica. Las fiestas más representativas son el Dulce Nombre de Jesús, el Carnaval de Corozal y el Festival del Pito Atravesao. Se concluye que se requieren estrategias promocionales que afiancen la identidad cultural de este lugar, teniendo en cuenta que hay algunos que no son autóctonos, por lo que se considera que las tradiciones se están perdiendo y es necesario rescatarlas.
The Influence of Three Endothelin-1 Polymorphisms on the Progression of IgA Nephropathy
Authors: Maixnerová Dita , Merta M. , Reiterová J. , Štekrová J. , Ryšavá R. , Obeidová H. , Viklický O. , Potměšil P. , Tesař V.
Published: January 2025

The clinical course of chronic renal diseases and their progression to ESRF is highly variable. Different candidate gene polymorphisms have been advocated as possible modulators of ESRF progression. Moreover, ET-1 has been suggested as a major promoting factor in renal disease. However, limited data are available regarding an association of three ET-1 SNP K198N, T1370G and 3A/4A with the progression of IgAN to ESRF. We examined a group of 122 pts with histologically proved IgAN (91 pts with normal renal function, 31 pts with ESRF), as a control group we used 132 genetically unrelated healthy subjects. Patients’ DNAs were genotyped for three ET-1 SNP: K198N, T-1370G and 3A/4A by means of PCR. The frequencies of different genotypes and ET-1 gene haplotypes were compared among control group, IgAN pts with normal renal function and IgAN pts with ESRF. The ET-1 genotype distribution showed no differences among the groups of IgAN with normal renal function (1. K198N – 63.74% KK, 32.97% KN, 3.3% NN; 2. TT – 68.13% TT, 28.57% TG, 3.3% GG; 3. 3A/4A – 42.22% 3A/3A, 50.0% 3A/4A, 7.69% 4A/4A ), IgAN with ESRF (1. K198N – 74.19% KK, 25.81% KN, 0% NN; 2. TT – 77.42% TT, 22.58% TG, 0% GG, 3. 3A/4A – 56.25% 3A/3A, 37.5% 3A/4A, 6.25% 4A/4A ) and the control group (1. K198N – 66.67% KK, 31.82% KN, 1.52% NN, 2. TT – 76.51% TT, 22.72% TG, 0.76% GG, 3. 3A/4A – 43.94% 3A/3A, 44.70% 3A/4A, 11.36% 4A/4A). The analysis of haplotypes showed that the frequency of G-198, G-1370 and 4A allele combination was significantly higher in comparison with the control group (P = 0.0056). We excluded the effect of K198N, T-1370G and 3A/4A polymorphisms of the ET-1 gene in single-gene analysis on the progression of IgAN to ESRF. A significant association of the GG4A haplotype with IgAN, demonstrated by haplotype reconstruction of the ET-1 gene, could suggest a role in the pathogenesis of IgAN.
Polonistyka międzykulturowa
Authors: Zduniak Małgorzata
Published: January 2025

Artykuł przybliża koncepcję polonistyki międzykulturowej. Ta naukowo-dydaktyczna praktyka prezentowana jest w odniesieniu do umiędzynarodowienia szkolnictwa wyższego w Polsce, cudzoziemców studiujących polonistykę w kraju i za granicą, przemian tożsamości filologii narodowej, a także niezębnych kompetencji metodycznych wykładowców pracujących ze studentami z zagranicy oraz programów kształcenia (filologia polska jako obca).
Od nauki języka do świadomości metalingwistycznej. Seminarium językoznawcze dla chińskojęzycznych studentów filologii polskiej jako obcej
Authors: Gębka-Wolak Małgorzata , Kaproń-Charzyńska Iwona , Kamper-Warejko Joanna , Bojałkowska Krystyna
Published: January 2025

Celem artykułu jest przedstawienie koncepcji, przebiegu i efektów seminarium licencjackiego o profilu językoznawczo-glottodydaktycznym, prowadzonego na studiach polonistycznych adresowanych do studentów chińskojęzycznych. Jego istotnym zadaniem było rozwijanie świadomości metalingwistycznej studentów-obcokrajowców. W artykule staramy się wykazać, że dzięki podjęciu w ramach prac licencjackich problematyki łączącej teoretyczne aspekty słowotwórstwa i praktyczne jego zastosowanie w nauczaniu języka polskiego jako obcego możliwe stało się z jednej strony harmonijne rozwijanie: a) wiedzy o budowie i funkcjonowaniu systemu językowego oraz b) kompetencji dotyczących prowadzenia badań lingwistycznych i metod nauczania polszczyzny, z drugiej – kształcenie umiejętności językowych.
Działania i strategie mediacyjne w przygotowaniu językowym kandydatów na studia w Polsce
Authors: Jasińska Agnieszka
Published: January 2025

W 2018 roku ukazał się Common European Framework of Reference for Languages – Companion Volume, kluczowy dokument związany z polityką językową w Europie. Zawiera on poszerzony opis działań i strategii językowych związanych z mediacją. Mediacja w nauczaniu rozumiana jest w trzech aspektach: mediacji tekstowej, pojęciowej i komunikacyjnej. W artykule zawarto również opis strategii mediacyjnych umożliwiających przetwarzanie tekstu. Wspomniano także o mediacji pedagogicznej. Artykuł przedstawia rolę mediacji w językowej edukacji kandydatów na studia w Polsce.
Kim jest „polski Prešeren” i czy Kubuś Puchatek podbiłby serca słoweńskich dzieci? Wykorzystanie nazw własnych w nauczaniu języka polskiego jako nierodzimego
Authors: Graf Magdalena , Nowak Marta
Published: January 2025

Glottodydaktyka polonistyczna weszła w dojrzały etap rozwoju, a w konsekwencji na rynku jest coraz więcej materiałów edukacyjnych, także profilowanych. Istotnym elementem edukacji polonistycznej stała się wiedza kulturowa oraz realioznawstwo,ponieważ język jest nierozerwalnie związany ze światem, który opisuje. Mimo coraz większej liczby dostępnych materiałów edukacyjnych i ich różnorodności, wciąż brakuje w glottodydaktyce materiałów poświęconych kulturowym nazwom własnym. Z tejprzyczyny przeprowadzono badania pilotażowe na grupie słoweńskich studentów uczących się języka polskiego jako obcego, które miały sprawdzić ich znajomość tychże nazw. Okazało się, że nawet wśród studentów polonistyki jest to wiedza zdecydowanie wymagająca uzupełnienia. Zaprezentowane badania będą kontynuowane w ramach projektu NAWA, a ich efektem będzie podręcznik oraz dostępny dla uczących się języka polskiego jako obcego kurs multimedialny poświęcony nazwom własnym w glottodydaktyce.