bluuebunny/crossref_metadata_2025 huggingface dataset:
AB INITIO NUCLEAR STRUCTURE CALCULATIONS OF p-SHELL NUCLEI WITH JISP16
Authors: MARIS PIETER , VARY JAMES P.
Published: June 2013

We review energies and magnetic moments of p-shell nuclei obtained with the ab initio No-Core Full Configuration (NCFC) approach using the JISP16 realistic nucleon–nucleon interaction. We present calculated ground state energies for all stable p-shell nuclei and selected unstable isotopes, as well as their magnetic moments. We also review excitation energies for narrow resonances of A = 6 to 9 nuclei. We compare our results with experimental data and with other ab initio calculations, where available. We illustrate how the decomposition of total angular momentum into intrinsic spin and orbital components provides insights into the structure of states and relationships among states. We illustrate the challenges of obtaining converged results for radii, quadrupole moments and B(E2) values.
STATISTICAL AND QUANTAL EFFECTS ON PAIRING PHASE TRANSITION IN THE CASE OF HOT EVEN–EVEN NEUTRON-RICH TIN ISOTOPES
Authors: KADI H. , HADDOUCHE A. , BENHAMOUDA N.
Published: June 2013

The thermal properties of Tin isotopes such as 68≤N≤78, are studied. The calculations are performed by means of the modified Lipkin–Nogami (MLN) approach that takes into account the thermal and quantal fluctuations. The obtained results are compared to the conventional finite-temperature Bardeen–Cooper–Schrieffer (FTBCS) approach and to the modified Bardeen–Cooper–Schrieffer (MBCS) method. The numerical results illustrate the effect of the statistical and quantal fluctuations on the description of the phenomenon of pairing phase transition.
ITÔ–WIENER CHAOS AND THE HODGE DECOMPOSITION ON AN ABSTRACT WIENER SPACE
Authors: YANG YUXIN
Published: June 2013

Using the structure of the Boson-Fermion Fock space and an argument taken from [P. Bieliavsky, M. Cahen, S. Gutt, J. Rawnsley and L. Schwachhofer, Symplectic connections, Int. J. Geom. Meth. Mod. Phys.3 (2006) 375–420], we give a new proof of the triviality of the L2 cohomology groups on an abstract Wiener space, alternative to that given by Shigekawa [De Rham–Hodge–Kodaira's decomposition on an abstract Wiener space, J. Math. Kyoto. Univ.26(2) (1986) 191–202]. We apply the representation theory of the symmetric group to characterize the spaces of exact and co-exact forms in their Boson-Fermion Fock space representation.
ON STOCHASTIC DOMINANCE OF NILPOTENT OPERATORS
Authors: MUDAKKAR SYEDA RABAB , UTEV SERGEY
Published: June 2013

In this paper, motivated by Nica and Speicher [Lectures on the Combinatorics of Free Probability, London Mathematical Society Lecture Note Series, Vol. 335 (Cambridge University Press, 2006)] and Kubo and Kuo [MRM-factors for the probability measures in the Meixner class, Infin. Dimens. Anal. Quantum Probab. Relat. Top.13 (2010) 525–550], we characterize a particular nilpotent case of a truncated forward shift operator by applying the technique of the random walks with repeated reflections and associated renewal equations. We also establish a stochastic order relationship by applying the crossing criteria.
ABUNDANCE OF THE SEMIGROUP OF ALL TRANSFORMATIONS OF A SET THAT REFLECT AN EQUIVALENCE RELATION
Authors: SUN LEI , WANG LIMIN
Published: June 2013

Let [Formula: see text] be the full transformation semigroup on a nonempty set X and E be an equivalence relation on X. We write [Formula: see text] Then T∃(X) is a subsemigroup of [Formula: see text]. In this paper, we proved that the semigroup T∃(X) is not abundant if X/E is infinite.
ON THOMPSON'S CONJECTURE FOR ALMOST SPORADIC SIMPLE GROUPS
Authors: WANG LINGLI , SHI WUJIE
Published: June 2013

Let G be a non-abelian group and N(G) be the set of conjugacy class sizes of G. In 1980s, Thompson posed the following conjecture: if M is a finite non-abelian simple group, G is a finite group with Z(G) = 1 and N(G) = N(M), then M ≅ G. Here, we prove Thompson's conjecture holds for all almost sporadic simple groups.
NONLOCAL SYMMETRIES, COMPACTON EQUATIONS, AND INTEGRABILITY
Authors: HERNÁNDEZ HEREDERO RAFAEL , REYES ENRIQUE G.
Published: June 2013

We review the theory of nonlocal symmetries of nonlinear partial differential equations and, as examples, we present infinite-dimensional Lie algebras of nonlocal symmetries of the Fokas–Qiao and Kaup–Kupershmidt equations. Then, we consider nonlocal symmetries of a family which contains the Korteweg–de Vries (KdV) and (a subclass of) the Rosenau–Hyman compacton-bearing K(m, n) equations. We find that the only member of the family which possesses nonlocal symmetries (of a kind specified in Sec. 3 below) is precisely the KdV equation. We take this fact as an indication that the K(m, n) equations are not integrable in general, and we use the formal symmetry approach of Shabat to check this claim: we prove that the only integrable cases of the full K(m, n) family are the KdV and modified KdV equations.
COMPLEXIFIER VERSUS FACTORIZATION AND DEFORMATION METHODS FOR GENERATION OF COHERENT STATES OF A 1D NLHO I: MATHEMATICAL CONSTRUCTION
Authors: ROKNIZADEH R. , HEYDARI H.
Published: June 2013

Three methods: complexifier, factorization and deformation, for construction of coherent states are presented for one-dimensional nonlinear harmonic oscillator (1D NLHO). Since by exploring the Jacobi polynomials [Formula: see text], bridging the difference between them is possible, we give here also the exact solution of Schrödinger equation of 1D NLHO in terms of Jacobi polynomials.
COMPLETENESS OF TRAJECTORIES OF RELATIVISTIC PARTICLES UNDER STATIONARY MAGNETIC FIELDS
Authors: CANDELA ANNA MARIA , ROMERO ALFONSO , SÁNCHEZ MIGUEL
Published: June 2013

The second-order differential equation [Formula: see text] on a Lorentzian manifold describes, in particular, the dynamics of particles under the action of an electromagnetic field F and a conservative force -∇V. We provide a first study on the extendability of its solutions, by imposing some natural assumptions.
OPEN VIRTUAL STRUCTURE CONSTANTS AND MIRROR COMPUTATION OF OPEN GROMOV–WITTEN INVARIANTS OF PROJECTIVE HYPERSURFACES
Authors: JINZENJI MASAO , SHIMIZU MASAHIDE
Published: June 2013

In this paper, we generalize Walcher's computation of the open Gromov–Witten invariants of the quintic hypersurface to Fano and Calabi–Yau projective hypersurfaces. Our main tool is the open virtual structure constants. We also propose the generalized mirror transformation for the open Gromov–Witten invariants, some parts of which are proven explicitly. We also discuss possible modification of the multiple covering formula for the case of higher-dimensional Calabi–Yau manifolds. The generalized disk invariants for some Calabi–Yau and Fano manifolds are shown and they are certainly integers after resummation by the modified multiple covering formula. This paper also contains the direct integration method of the period integrals for higher-dimensional Calabi–Yau hypersurfaces in the Appendix.
SIMPLE SYNTHESIS OF UNIFORM α-Fe2O3 MICROSPHERES WITH EXCELLENT PHOTOCATALYTIC PERFORMANCE USING POLY (N-VINYL-2-PYRROLIDONE)
Authors: ZHANG TING-TING , GUO TING-TING , WU ZHI-PING , YANG SI-WEI , WANG ZHOU-FENG , LIAO FANG
Published: June 2013

In this paper, a new simple approach has been developed for the preparation of α- Fe 2 O 3 microspheres by a facile hydrothermal method using PVP as a surfactant. Uniform α- Fe 2 O 3 microspheres could be routinely synthesized through solvothermal approach by controlling the PVP/ FeCl 3⋅6 H 2 O ratio. The as-obtained α- Fe 2 O 3 microspheres exhibit high efficiency on the decolorization of RhB aqueous solution in the presence of H 2 O 2 at room temperature.
FAST MULTIPOLE BOUNDARY ELEMENT METHOD FOR THREE DIMENSIONAL ELECTROMAGNETIC SCATTERING PROBLEM
Authors: WANG S. B. , ZHENG H. H. , XIAO J. J. , LIN Z. F. , CHAN C. T.
Published: June 2013

We developed a fast numerical algorithm for solving the three-dimensional vectorial Helmholtz equation that arises in electromagnetic scattering problems. The algorithm is based on electric field integral equations and is essentially a boundary element method. Nyström's quadrature rule with a triangular grid is employed to linearize the integral equations, which are then solved by using a right-preconditioned iterative method. We apply the fast multipole technique to accelerate the matrix-vector multiplications in the iterations. We demonstrate the broad applications and accuracy of this method with practical examples including dielectric, plasmonic and metallic objects. We then apply the method to investigate the plasmonic properties of a silver torus and a silver split-ring resonator under the incidence of an electromagnetic plane wave. We show the silver torus can be used as a trapping tool to bind small dielectric or metallic particles.
FACILE APPROACHES FOR CONSTRUCTING BLUE/DEEP-BLUE TPE-BASED SOLID EMITTERS
Authors: HUANG JING , LI QIANQIAN , LI ZHEN
Published: June 2013

The intriguing phenomenon of aggregation-induced emission (AIE), first reported by Tang et al. in 2001, has been demonstrated as an effective way to tackle the notorious aggregation-caused quenching (ACQ) effect and aroused a new research topic of AIE materials as promising candidates for OLEDs and bioprobes. Among the archetypal AIE molecules, tetraphenylethene (TPE) enjoys the advantages of facile synthesis and outstanding AIE effect. Although lots of TPE-based luminogens with excellent electroluminescence performance have been developed, blue AIE luminogens are still scarce for the intrinsic extension of intramolecular conjugation. In this paper, we mainly review our recent work on the construction of blue- or deep-blue TPE-based solid emitters for OLEDs. The facile synthetic approaches and the device performance of the resulting materials are well demonstrated.
Recycling Glass Cullet from Waste CRTs for the Production of High Strength Mortars
Authors: Maschio Stefano , Tonello Gabriele , Furlani Erika
Published: June 2013

The present paper reports on the results of some experiments dealing with the recycling of mixed cathode ray tube (CRT) glass waste in the production of high-strength mortars. Waste CRT glass cullet was previously milled, and sieved, and the only fine fraction was added to the fresh mortar in order to replace part of the natural aggregate. The addition of superplasticizer was also investigated. All hydrated materials displayed high compressive strength after curing. Samples containing CRT mixed glass showed a more rapid increase of strength with respect to the reference compositions, and materials with a superplasticizer content of 1% showed the best overall performance due to the favourable influence of the small glass particles which increase the amount of silicate hydrated produced. The induced coupled plasma (ICP) analysis made on the solutions, obtained from the leaching tests, confirmed the low elution of hazardous elements from the monolithic materials produced and consequently their possible environmental compatibility.
Controllability Criteria for Linear Fractional Differential Systems with State Delay and Impulses
Authors: Zhang Hai , Cao Jinde , Jiang Wei
Published: June 2013

This paper is concerned with the controllability of linear fractional differential systems with delay in state and impulses. The factors of such systems including fractional derivative, impulses, and delay are taken into account synchronously. The expression of state response for such systems is derived, and the sufficient and necessary conditions of controllability criteria are established. Both the proposed criteria and illustrative examples show that the controllability property of the linear systems is dependent neither on the order of fractional derivative, on delay nor on impulses.
Two Novel 30K Proteins Overexpressed in Baculovirus System and Their Antiapoptotic Effect in Insect and Mammalian Cells
Authors: Yu Wei , Li Qing , Yao Yuhua , Quan Yanping , Zhang Yaozhou
Published: June 2013

The 30K family of proteins is important in energy metabolism and may play a role in inhibiting cellular apoptosis in silkworms (Bombyx mori). Several 30K-family proteins have been identified. In this study, two new silkworm genes, referred to asSlp(NM 001126256) andLsp-t(NM 001043443), were analyzed by a bioinformatics approach according to the sequences of 30K proteins previously reported in the silkworm. Both Slp and Lsp-t shared more than 41% amino acid sequence homology with the reported 30K proteins and displayed a conserved domain consistent with that of lipoprotein-11. Additionally, the cDNA sequences of bothSlpandLsp-twere obtained from the fat bodies of silkworm larvae by reverse transcription polymerase chain reaction. Both genes were expressed in BmN cells using the Bac-to-Bac system. Purified Slp and Lsp-t were added to cultured BmN and human umbilical vein endothelial cells (HUVEC) that were treated with H2O2. Both Slp and Lsp-t significantly enhanced the viability and suppressed DNA fragmentation in H2O2treated BmN and HUVEC cells. This study suggested that Slp and Lsp-t exhibit similar biological activities as their known 30K-protein counterparts and mediate an inhibitory effect against H2O2-induced apoptosis.
Expression of SET Protein in the Ovaries of Patients with Polycystic Ovary Syndrome
Authors: Boqun Xu , Xiaonan Dai , YuGui Cui , Lingling Gao , Xue Dai , Gao Chao , Feiyang Diao , Jiayin Liu , Gao Li , Li Mei , Zhang Yuan , Ma Xiang
Published: June 2013

Background. We previously found that expression of SET gene was up-regulated in polycystic ovaries by using microarray. It suggested that SET may be an attractive candidate regulator involved in the pathophysiology of polycystic ovary syndrome (PCOS). In this study, expression and cellular localization of SET protein were investigated in human polycystic and normal ovaries.Method. Ovarian tissues, six normal ovaries and six polycystic ovaries, were collected during transsexual operation and surgical treatment with the signed consent form. The cellular localization of SET protein was observed by immunohistochemistry. The expression levels of SET protein were analyzed by Western Blot.Result. SET protein was expressed predominantly in the theca cells and oocytes of human ovarian follicles in both PCOS ovarian tissues and normal ovarian tissues. The level of SET protein expression in polycystic ovaries was triple higher than that in normal ovaries(P<0.05).Conclusion. SET was overexpressed in polycystic ovaries more than that in normal ovaries. Combined with its localization in theca cells, SET may participate in regulating ovarian androgen biosynthesis and the pathophysiology of hyperandrogenism in PCOS.
Alport's Syndrome in Pregnancy
Authors: Mehta Suchita , Saifan Chadi , Abdellah Marie , Choueiry Rita , Nasr Rabih , El-Sayegh Suzanne
Published: June 2013

Background. Alport's syndrome is an X-linked hereditary disorder affecting the glomerular basement membrane associated with ocular and hearing defects. In women, the disease is much less severe compared to that in men. However, women with Alport's syndrome can have an accelerated form of their disease during pregnancy with worsening of kidney function and can also develop preeclampsia. There are only four described cases of Alport's syndrome in pregnancy.Case Presentation. 20-year-old woman with a history of Alport's syndrome, which during pregnancy worsened resulting in hypertension, proteinuria, and acute kidney injury. Fortunately, there was complete resolution of the proteinuria and kidney injury with delivery, and the patient did not require any renal replacement therapy.Conclusion. One of the four reported cases had an accelerated form of the disease during pregnancy with rapid progression of kidney injury and end-stage renal disease. There are no definite guidelines to monitor these patients during pregnancy. Further studies are required to understand the exact pathophysiology of kidney damage that occurs in pregnant women with Alport's syndrome. This may give us some insight into the prognostic predictors, so that we can monitor these women more thoroughly and prevent adverse outcomes.
Cadmium Toxicity and Treatment
Authors: Bernhoft Robin A.
Published: June 2013

Cadmium is a heavy metal of considerable toxicity with destructive impact on most organ systems. It is widely distributed in humans, the chief sources of contamination being cigarette smoke, welding, and contaminated food and beverages. Toxic impacts are discussed and appear to be proportional to body burden of cadmium. Detoxification of cadmium with EDTA and other chelators is possible and has been shown to be therapeutically beneficial in humans and animals when done using established protocols.
Characterization of Antibiotic-Loaded Alginate-Osa Starch Microbeads Produced by Ionotropic Pregelation
Authors: Fontes Gizele Cardoso , Calado Verônica Maria Araújo , Rossi Alexandre Malta , Rocha-Leão Maria Helena Miguez da
Published: June 2013

The aim of this study was to characterize the penicillin-loaded microbeads composed of alginate and octenyl succinic anhydride (OSA) starch prepared by ionotropic pregelation with calcium chloride and to evaluate theirin vitrodrug delivery profile. The beads were characterized by size, scanning electron microscopy (SEM), zeta potential, swelling behavior, and degree of erosion. Also, the possible interaction between penicillin and biopolymers was investigated by differential scanning calorimetry (DSC), powder X-ray diffraction (XRD), and Fourier transform infrared (FTIR) analysis. The SEM micrograph results indicated a homogeneous drug distribution in the matrix. Also, based on thermal analyses (TGA/DSC), interactions were detected between microbead components. Although FTIR spectra of penicillin-loaded microbeads did not reveal the formation of new chemical entities, they confirmed the chemical drug stability. XRD patterns showed that the incorporated crystalline structure of penicillin did not significantly alter the primarily amorphous polymeric network. In addition, the results confirmed a prolonged penicillin delivery system profile. These results imply that alginate and OSA starch beads can be used as a suitable controlled-release carrier for penicillin.
Kinematic Analysis of a 3-Axis Parallel Manipulator: The P3
Authors: Chen Qiaohong , Chen Zhi , Chai Xinxue , Li Qinchuan
Published: June 2013

This paper presents kinematic analysis of a 3-axis parallel manipulator, called P3. The P3 parallel manipulator is developed based on a 3-PRRU parallel mechanism, where P denotes prismatic pair, R revolute pair, and U universal joint. The P3 parallel manipulator can undergo two rotations and one translation without parasitic motion. First, a brief description of the P3 is presented. Then, forward and inverse kinematic solutions of the P3 are derived. Parasitic motion is discussed. The Jacobian matrix is obtained based on the velocity equations. Further, singular configurations of the P3 are identified. A special configuration where the actuation fails is also detected based on screw theory. The workspace of P3 is investigated.
A History of the Development ofBrucellaVaccines
Authors: Avila-Calderón Eric Daniel , Lopez-Merino Ahidé , Sriranganathan Nammalwar , Boyle Stephen M. , Contreras-Rodríguez Araceli
Published: June 2013

Brucellosis is a worldwide zoonosis affecting animal and human health. In the last several decades, much research has been performed to develop saferBrucellavaccines to control the disease mainly in animals. Till now, no effective human vaccine is available. The aim of this paper is to review and discuss the importance of methodologies used to developBrucellavaccines in pursuing this challenge.
Tetrazolium/Formazan Test as an Efficient Method to Determine Fungal Chitosan Antimicrobial Activity
Authors: Moussa Shaaban H. , Tayel Ahmed A. , Al-Hassan Ahmed A. , Farouk A.
Published: June 2013

Fungal chitosan was extracted from Aspergillus niger mycelia. The produced chitosan was characterized with deacetylation degree of 89.2%, a molecular weight of 2.4 × 104 Da, and 96.0% solubility in 1% acetic acid solution. The antibacterial activity of fungal chitosan was evaluated against two foodborne pathogens, that is, Salmonella typhimurium and Staphylococcus aureus, using the established antibacterial assays, for example, zone of growth inhibition and agar plat count tests, and using 2,3,5,-triphenyltetrazolium chloride (TTC) as chromogenic marker for qualitative and quantitative determining of antibacterial potentiality. The TTC (0.5% w/v) was added, at concentration of 10%, to cultured broth, containing chitosan with different concentrations then the formed formazan was separated. The formation of red formazan could be considered as a qualitative indication for antibacterial activity, whereas the measurement of color intensity for the resuspended red formazan, using spectrophotometer at 480 nm, provided a quantitative evidence for the strength of the used antibacterial agent.
Regarding the rapidity, technical simplicity, and cost-effectiveness, TTC assay could be recommended as an efficient alternative method for qualitative and quantitative determination of chitosan antibacterial activity and could be suggested for general evaluation of antibacterial agents.
Antioxidant and Renoprotective Effects ofSpirogyra neglecta(Hassall) Kützing Extract in Experimental Type 2 Diabetic Rats
Authors: Ontawong Atcharaporn , Saowakon Naruwan , Vivithanaporn Pornpun , Pongchaidecha Anchalee , Lailerd Narissara , Amornlerdpison Doungporn , Lungkaphin Anusorn , Srimaroeng Chutima
Published: June 2013

Spirogyra neglectaextract (SNE) has shown antihyperglycemia and antihyperlipidemia in type 2 diabetic mellitus (T2DM) rats. This study investigated the antioxidant and renoprotective effects of SNE in T2DM rats induced by high-fat diet with low-single dose streptozotocin. T2DM rats were fed daily with SNE (0.25, 0.5, and 1 g/kg BW) for 12 weeks. Renal morphology, malondialdehyde levels, qPCR, and western blotting were analyzed. Renal cortical slices were used to determine renal transport of organic anions, which are estrone sulfate andpara-aminohippurate, mediated through organic anion transporter 3-Oat3. Insulin and PKCζwere known to activate Oat3 function while it was inhibited by PKCα. Compared to T2DM, plasma glucose, triglyceride, insulin resistance, renal morphology, and malondialdehyde levels were significantly improved by SNE supplementation. Reduced glutathione peroxidase and nuclear factorκB expressions were related to antioxidant effect of SNE. Oat3 mRNA and protein were not different among groups, but insulin-stimulated rOat3 followed by anion uptakes was abolished in T2DM. This was restored in the slices from SNE treatment. The mechanism of SNE-improved Oat3 was associated with PKCαand PKCζexpressions and activities. These findings indicate that SNE has beneficial effects on renal transport through antioxidant enzymes and PKCs in T2DM rats.
Classification of Ordered Type Soliton Metric Lie Algebras by a Computational Approach
Authors: Kadıoğlu Hülya
Published: June 2013

We classify some soliton nilpotent Lie algebras and possible candidates in dimensions 8 and 9 up toisomorphy.We focus on type of derivations, where is the dimension of the Lie algebras. We present algorithms to generate possible algebraic structures.
Diffusion in Replica Healthy and Emphysematous Alveolar Models Using Computational Fluid Dynamics
Authors: Harding Edward M. , Berg Emily J. , Robinson Risa J.
Published: June 2013

Deposition of nanosized particles in the pulmonary region has the potential of crossing the blood-gas barrier. Experimental in vivo studies have used micron-sized particles, and therefore nanoparticle deposition in the pulmonary region is not well understood. Furthermore, little attention has been paid to the emphysematous lungs, which have characteristics quite different from the healthy lung. Healthy and emphysematous replica acinus models were created from healthy and diseased human lung casts using three-dimensional reconstruction. Particle concentration and deposition were determined by solving the convective-diffusion equation numerically for steady and unsteady cases. Results showed decreased deposition efficiencies for emphysema compared to healthy lungs, consistent with the literature and attributed to significant airway remodeling in the diseased lung. Particle diffusion was found to be six times slower in emphysema compared to healthy model. The unsteady state simulation predicted deposition efficiencies of 96% in the healthy model for the 1 nm and 3 nm particles and 94% and 93% in the emphysema model for the 1 nm and 3 nm particles, respectively. Steady state was achieved in less than one second for both models. Comparisons between steady and unsteady predictions indicate that a steady-state simulation is reasonable for predicting particle transport under similar conditions.
Evidence-Based Chinese Medicine for Hypertension
Authors: Wang Jie , Xiong Xingjiang
Published: June 2013

Hypertension is an important worldwide public -health challenge with high mortality and disability. Due to the limitations and concerns with current available hypertension treatments, many hypertensive patients, especially in Asia, have turned to Chinese medicine (CM). Although hypertension is not a CM term, physicians who practice CM in China attempt to treat the disease using CM principles. A variety of approaches for treating hypertension have been taken in CM. For seeking the best evidence of CM in making decisions for hypertensive patients, a number of clinical studies have been conducted in China, which has paved the evidence-based way. After literature searching and analyzing, it appeared that CM was effective for hypertension in clinical use, such as Chinese herbal medicine, acupuncture, moxibustion, cupping, qigong, and Tai Chi. However, due to the poor quality of primary studies, clinical evidence is still weak. The potential benefits and safety of CM for hypertension still need to be confirmed in the future with well-designed RCTs of more persuasive primary endpoints and high-quality SRs. Evidence-based Chinese medicine for hypertension still has a long way to go.
Epitope Mapping of Metuximab on CD147 Using Phage Display and Molecular Docking
Authors: He Bifang , Mao Canquan , Ru Beibei , Han Hesong , Zhou Peng , Huang Jian
Published: June 2013

Metuximab is the generic name of Licartin, a new drug for radioimmunotherapy of hepatocellular carcinoma. Although it is known to be a mouse monoclonal antibody against CD147, the complete epitope mediating the binding of metuximab to CD147 remains unknown. We panned the Ph.D.-12 phage display peptide library against metuximab and got six mimotopes. The following bioinformatics analysis based on mimotopes suggested that metuximab recognizes a conformational epitope composed of more than 20 residues. The residues of its epitope may include T28, V30, K36, L38, K57, F74, D77, S78, D79, D80, Q81, G83, S86, N98, Q100, L101, H102, G103, P104, V131, P132, and K191. The homology modeling of metuximab and the docking of CD147 to metuximab were also performed. Based on the top one docking model, the epitope was predicted to contain 28 residues: AGTVFTTV (23–30), I37, D45, E84, V88, EPMGTANIQLH (92–102), VPP (131–133), Q164, and K191. Almost half of the residues predicted on the basis of mimotope analysis also appear in the docking result, indicating that both results are reliable. As the predicted epitopes of metuximab largely overlap with interfaces of CD147-CD147 interactions, a structural mechanism of metuximab is proposed as blocking the formation of CD147 dimer.
A Preliminary Investigation of Depression and Kidney Functioning in Patients with Chronic Kidney Disease
Authors: Cukor Daniel , Fruchter Yvette , Ver Halen Nisha , Naidoo Shivana , Patel Ankita , Saggi Subodh J.
Published: June 2013

Background: The incidence and prevalence of Chronic Kidney Disease (CKD) is growing rapidly. Understanding the factors associated with declining renal function is of clinical significance. The current study's main goal was to identify variables that could predict decline in glomerular filtration rate (GFR) over time in outpatients with varying stages of CKD. Methods: Seventy CKD patients completed psychological questionnaires and medical variables were extracted from the medical charts. Follow-up GFR was collected 6 months later. CKD patients with elevated depression scores were compared to patients with subclinical depression on medical and psychological variables. Results: Average Beck Depression Inventory (BDI) score was 10.0 ± 7.8, placing the mean below the cut-off for clinical elevation. GFR was significantly different for the two groups (nondepressed, 40.0 ± 11.3 vs. depressed 29.6 ± 8.9; p < 0.05). Similarly, patients with elevated depression scores reported lower quality of life (Short Form 36 Health Survey; p < 0.05) inferior social support (Interpersonal Support Evaluation List; p < 0.05), and worse community integration (Community Integration Questionnaire; p < 0.05). Utilizing a regression, with a model correcting for baseline GFR, the BDI explained 19% of the variance in GFR score (t = -2.0, p < 0.05) for subjects with decreased GFR. Conclusions: Increased levels of preexisting depression were associated with inferior quality of life, social support and kidney functioning. Depression scores explained a significant amount of variance in GFR scores at 6 months even when corrected for baseline variability. Elevated depression scores are prevalent in CKD populations and further research on the impact of depression interventions is warranted.
Does a Patent Foramen Ovale Influence Cognitive Function in Dialysis Patients?
Authors: George Sudhakar , Holt Stephen , Medford Nick , Hildick-Smith David
Published: June 2013

Background: Patients with chronic kidney disease on dialysis treatment have poorer cognitive function than age- and sex-matched controls. One proposed mechanism is cerebral microembolisation due to material from the dialysis circuit crossing a patent foramen ovale (PFO). Methods: Cognitive testing was carried out in haemodialysis (HD) patients and peritoneal dialysis (PD) patients. Transthoracic echocardiography was used to identify PFO. Follow-up testing 1 year later enabled comparison of cognitive decline between patients with and without a PFO, and between those undergoing different dialysis modalities. Results: 80 patients (aged 60.4 ± 15.0 years) were recruited (51 HD patients and 29 PD controls). A PFO was found in 21% of patients. 83% of dialysis patients suffered a decline in one or more cognitive function tests over 1 year. There was a significant difference in only one test between HD patients with or without a PFO. PD patients showed a more rapid cognitive decline than those on HD. Conclusions: Cognitive decline in dialysis patients is rapid and affects most patients. The presence of a PFO made only subtle differences to the rates of cognitive decline during 1 year of follow-up. Patients with a PFO should not be prevented from considering HD because of concerns of cerebral decline due to microembolisation.
Vision Loss following Intraocular Listeriosis Associated with Contaminated Cantaloupe
Authors: Ibraheem Mam , Vance Sushma , Jackson Kelly A. , Ettestad Paul , Smelser Chad , Silk Benjamin
Published: June 2013

Intraocular listeriosis, a rare manifestation of invasive listeriosis, has a poor visual prognosis. We report an intraocular listeriosis case related to a multistate outbreak associated with contaminated cantaloupe. Increasing awareness of rare listeriosis presentations might facilitate timely diagnosis and treatment, and case reporting can clarify medical and epidemiologic aspects of listeriosis.
In vivo Imaging of Sarcoptes scabiei Infestation Using Optical Coherence Tomography
Authors: Banzhaf Christina Alette , Themstrup Lotte , Ring Hans Christian , Welzel Julia , Mogensen Mette , Jemec Gregor Borut Ernst
Published: June 2013

Background:Sarcoptes scabiei can be visualized with different imaging tools. Optical coherence tomography (OCT) may have the potential to describe the changes in skin morphology due to scabies infestation and visualize the parasite. Methods: Five patients from the Departments of Dermatology, Augsburg, Germany, and Roskilde, Denmark, were OCT scanned (VivoSight®; Michelson Diagnostics Ltd., UK). Mites were identified by epiluminescence and light microscopy to confirm the diagnosis. Results: OCT identified S. scabiei mites in all patients in vivo. Mites and burrows were visualized, and some detail on burrow content was provided. Conclusion: OCT can visualize S. scabiei mites in vivo, suggesting that it may be used to study the biology of the mites in vivo and provide early assessment of scabicide therapy. OCT is able to visualize structures in the skin with an 8-µm resolution. Therefore, this technology could potentially allow rapid, non-invasive, in vivo diagnosis and analysis of infestations.
Income Polarization in Asia
Authors: Gochoco-Bautista Maria Socorro , Bautista Carlos C. , Maligalig Dalisay S. , Sotocinal Noli R.
Published: June 2013

The subject of this study is income polarization, an important but neglected dimension of income distribution. Estimates of two measures of income polarization are obtained for the population, rural, and urban sectors using household survey data on expenditures per capita for a sample of Asian countries. The findings include the following: Income polarization and inequality, the latter measured using the Gini coefficient, are highly positively correlated; in most countries, urban income polarization is higher than rural income polarization; and lastly, higher rates of growth in GDP and per capita GDP, higher levels of educational attainment of household heads, and high rates of employment in manufacturing may be important in keeping income polarization at low levels.
Predicting an Orchestral Conductor's Baton Movements Using Machine Learning
Authors: Dansereau Donald G. , Brock Nathan , Cooperstock Jeremy R.
Published: June 2013

Telematic musical performance, in which performers at two or more sites collaborate via networked audio and video, suffers significantly from latency. In the extreme case, performers at all sites slow to match their delayed counterparts, resulting in a steadily decreasing tempo. Introducing video of a conductor does not immediately solve the problem, as conductor video is also subjected to network latencies. This article lays the groundwork for an alternative approach to mitigating the effects of latency in distributed orchestral performances, based on generation of a predicted version of the conductor's baton trajectory. The prediction step is the most fundamental problem in this scheme, for which we propose the use of conventional machine learning techniques. Specifically, we demonstrate a particle filter and an extended Kalman filter that each track the location of the baton's tip and predict it multiple beats into the future; we compare these with a conventional feature-based method. We also describe a generic two-part framework that prescribes the incorporation of rehearsal data into a probabilistic model, which is then adapted during live performance. Finally, we suggest a framework and experimental methodology for establishing perceptually based metrics for predicted baton paths. Note that the perceptual efficacy of the presented methods requires experimental confirmation beyond the scope of this article.
Synchronizing Sequencing Software to a Live Drummer
Authors: Robertson Andrew , Plumbley Mark D.
Published: June 2013

This article presents a method of adjusting the tempo of a music software sequencer so that it remains synchronized with a drummer's musical pulse. This allows music sequencer technology to be integrated into a band scenario without the compromise of using click tracks or triggering loops with a fixed tempo. Our design implements real-time mechanisms for both underlying tempo and phase adjustment using adaptable parameters that control its behavior. The aim is to create a system that responds to timing variations in the drummer's playing but is also stable during passages of syncopation and fills. We present an evaluation of the system using a stochastic drum machine that incorporates a level of noise in the underlying tempo and phase of the beat. We measure synchronization error between the output of the system and the underlying pulse of the drum machine and contrast this with other real-time beat trackers. The software, B-Keeper, has been released as a Max for Live device, available online at www.b-keeper.org .
Towards Computer-Assisted Flamenco Transcription: An Experimental Comparison of Automatic Transcription Algorithms as Applied to A Cappella Singing
Authors: Gómez Emilia , Bonada Jordi
Published: June 2013

This article deals with automatic transcription of flamenco music recordings—more specifically, a cappella singing. We first study the specifics of flamenco singing and propose a transcription system based on fundamental frequency and energy estimation, which incorporates an iterative strategy for note segmentation and labeling. The proposed approach is evaluated on a music collection of 72 performances, including a variety of singers and recording conditions, and the presence or absence of percussion, background voices, and noise. We obtain satisfying results for the different approaches tested, and our system outperforms a state-of-the-art approach designed for other singing styles. In this study, we discuss the difficulties found in transcribing flamenco singing and in evaluating the obtained transcriptions, we analyze the influence of the different steps of the algorithm, and we state the main limitations of our approach and discuss challenges for future studies.
Ornithodoros guaporensis (Acari, Ixodida: Argasidae), a new tick species from the Guaporé River Basin in the Bolivian Amazon
Authors: VENZAL SANTIAGO NAVA, JOSÉ M. , TERASSINI FLAVIO A. , MANGOLD ATILIO J. , CAMARGO LUIS M. A. , CASÁS GUSTAVO , LABRUNA MARCELO B.
Published: June 2013

The soft tick Ornithodoros guaporensis n. sp. (Acari: Ixodida: Argasidae) is described from larvae and adults. Morpho-logical analysis and 16S rDNA sequences are provided. Adults were collected from a rocky fissure inhabited by bats lo-cated in the Amazonian forest in north-eastern Bolivia (Beni Department) close to the Guaporé River. Larvae were obtained from eggs laid by females collected in the field, and which were fed on rabbits in the laboratory. Larvae of O. guaporensis are morphologically closely related to Ornithodoros rioplatensis, Ornithodoros puertoricensis and Orni-thodoros talaje. Larvae of O. guaporensis and O. rioplatensis can be separated from O. puertoricensis and O. talaje by the number of pairs of dorsal setae (20 in O. guaporensis and O. rioplatensis, 18 in O. puertoricensis and 17 in O. talaje). Larvae of O. guaporensis and O. rioplatensis can be differentiated by the medial dental formula (2/2 in O. guaporensis and 3/3 in O. rioplatensis) and the apex of the hypostome, which is more pointed in O. rioplatensis than in O. guaporensis. The Principal Component Analysis performed with morphometric characters of larvae showed a clear separation among O. guaporensis, O. rioplatensis, O. puertoricensis and O. talaje. Significant morphological differences among adults of these four species were not found. The analysis of the 16S rDNA sequences allowed for the differentiation between O. guaporensis and the remaining Neotropical species of the family Argasidae.
The spider-like katydid Arachnoscelis (Orthoptera: Tettigoniidae: Listroscelidinae): anatomical study of the genus
Authors: MONTEALEGRE-Z FERNANDO , CADENA-CASTAÑEDA OSCAR J. , CHIVERS BENEDICT
Published: June 2013

This paper provides some observations on the anatomy of the neotropical katydid Arachnoscelis arachnoides Karny (In-secta: Orthoptera: Tettigoniidae). Arachnoscelis is a genus of predaceous katydids that comprise species that resemble spi-ders in their general body appearance. The type species, A. arachnoids, was described in 1891 from a single male collected in Colombia. Following the original description, these creatures were never found again, and were thought to have gone extinct or mistakenly assigned to the type locality. But between 1891 and 2012 four more species were described and in-correctly assigned to Arachnoscelis based on a similarity of body form. In this paper we present an anatomical comparai-son of Arachnoscelis and its relatives, and propose that Arachnoscelis should be treated as a monotypic genus. This implies that other species previously described in Arachnoscelis, should be placed in different genera.
Molecular analysis validates of some informal morphological groups of Pagurus (Fabricius, 1775) (Anomura: Paguridae) from South America
Authors: OLGUÍN NICOLE , MANTELATTO FERNANDO LUIS
Published: June 2013

The systematics of the hermit crab genus Pagurus is complex, with a long history of taxonomic rearrangements. This group, with worldwide distribution, encompasses a large number of morphologically heterogeneous species. A total of 173 currently recognized species have been morphologically organized into 11 informal groups, in attempts to establish internal stability. This arrangement and the relationships among species of each informal group have remained obscure and have never been evaluated from a molecular phylogenetic viewpoint. Attempts to resolve these high-level classifica-tion problems have been restricted to morphological studies, with no satisfactory results because of the extensive overlap of the characters used. We evaluated the phylogenetic position of some of these informal groups of species of Pagurus occurring along the Pacific and Atlantic coasts of South America, using partial fragments of two molecular markers (16S mtDNA and Histone 3 nDNA). Our results indicated a clear polyphyletic arrangement of Pagurus; at the same time, the internal clades fit perfectly with pre-established informal morphological groups from South America, which may warrant a formal taxonomic subdivision of the genus. Additionally, the species belonging to the “provenzanoi group” clearly fit within a different taxon and should be reviewed. Also, the presence of the genus Propagurus in the ingroup could be in-terpreted by non-exclusive hypotheses: from one point of view, the genus Propagurus is nested within Pagurus, and the-refore Pagurus is not valid as currently composed; or possibly, that more than one genus should be recognized among the South American species presently assigned to Pagurus. This latter perspective accords with the proposal to restrict Pagu-rus to only a few species.
A new subspecies of the subgenus Ecdyonurus Eaton, 1868 (Ephemeroptera: Heptageniidae) from the East of Ukraine
Authors: MARTYNOV ALEXANDER V. , GODUNKO ROMAN J.
Published: June 2013

Ecdyonurus dispar gratificus ssp. nov. is reported from several small streams and rivers within the Donetsk Ridge (East of Ukraine). The new subspecies is described and illustrated on larvae and reared adults of both sexes. SEM photographs of the egg structures are presented. Critical diagnostic characters distinguishing the new subspecies from other represen-tatives of the subgenus Ecdyonurus Eaton, 1868 and especially from the nominal subspecies are discussed. The data on the biology and distribution are presented.
Three new species of the genus Neophyllobius Berlese (Acari: Camerobiidae) from Southern and Southwestern Iran
Authors: KHANJANI MOHAMMAD
Published: June 2013

Three new species of the genus Neophyllobius Berlese, 1886 are described and illustrated from Iran: Neophyllobius ed-wardi sp. nov. and Neophyllobius seemani sp. nov. collected from soil under oak trees; and Neophyllobius dogani sp. nov. collected from soil under Astragalus bushes. A key to the species of Iran is provided.
Revision of the ant genus Myrmoteras of the Indo-Chiese Peninsula (Hymenoptera: Formicidae: Formicinae)
Authors: BUI VIET TUAN , EGUCHI KATSUYUKI , YAMANE SEIKI
Published: June 2013

The Indo-Chinese species of the genus Myrmoteras are revised. We recognise one species in the subgenus Myagroteras and six species in the subgenus Myrmoteras from Vietnam, Myanmar and Thailand. Five new species are described based on the worker caste: M. concolor, M. jaitrongi, M. namphuong, M. opalinum, and M. tomimasai, all belonging to the sub-genus Myrmoteras.
Syncope for phlebologists
Authors: Mowatt-Larssen Eric
Published: June 2013

Emergencies during phlebology procedures are rare. Nonetheless, a phlebologist needs to be prepared to manage such a situation (like syncope due to anaphylaxis) if it occurs, to distinguish a true emergency from a more benign scenario (like vasovagal syncope), and even to manage an emergency unrelated causally to the procedure itself (like a heart dysrhythmia which happens to occur during sclerotherapy). The focus of such preparations should be actions and information which affect patient outcomes. Physician mental and even medical team rehearsal of such scenarios can improve phlebologist and team responses. This article discusses the differential diagnosis and management of the patient with syncope in a phlebology practice, with emphasis on anaphylaxis.
Acute myeloid leukemia creates an arginase-dependent immunosuppressive microenvironment
Authors: Mussai Francis , De Santo Carmela , Abu-Dayyeh Issa , Booth Sarah , Quek Lynn , McEwen-Smith Rosanna M. , Qureshi Amrana , Dazzi Francesco , Vyas Paresh , Cerundolo Vincenzo
Published: June 2013

Key Points

AML blasts have an arginase-dependent ability to inhibit T-cell proliferation and hematopoietic stem cells. AML blasts have an arginase-dependent ability to modulate the polarization of monocytes.
Properties of solutions of fourth-order differential equations with boundary conditions
Authors: Saker Samir H , Agarwal Ravi P , O’Regan Donal
Published: June 2013

In this paper, we establish some sufficient conditions for(2,2)-disconjugacy and study the distribution of zeros of nontrivial solutions of fourth-order differential equations. The results are extended to cover some boundary value problems in bending of beams. The main results are proved by making use of a generalization of Hardy’s inequality and some Opial-type inequalities. Some examples are considered to illustrate the main results.

MSC:34K11, 34C10.