bluuebunny/crossref_metadata_2025 huggingface dataset:
Pharmaceutical Standardisation and Physicochemical Analysis of Krimighatini Vati
Authors: Manju Raj K  , T.D. Sreekumar
Published: April 2023

Standardization is the process for the establishment of standard for a particular or drug. Standardization in Ayurvedic formulation mainly deals with ensuring standards for the quality and purity of raw materials, quality control during the drug manufacturing process, production of a good quality finished product and storage and distribution to maintain the quality of the final product. Standard of an Ayurvedic product can be assessed only by analyzing the analytical parameters of raw drugs, drugs after preprocessing and the finished products. Krimighatini vati explained in Rasendra chintamani is an antihelminth preparation explained in Rasendra Chintamani krimirogadhikara. It contains Parada- 1part, Gandhaka- 2 parts, Ajamoda -3 parts, Vidanga bheeja- 4 parts, Palaasha bheeja- 5parts, and Kaarsakara beeja- 6 parts. It is similar to Krimimudgara rasa that is available in market but differs in proportion of Palaasha beeja and Karaskara beeja. Present study aims to standardize Krimighatini vati after preparing the medicine according to the method explained in Ayurveda samhithas. Preprocessing of the Gulika includes, Shodhana of Hingula, Gandhaka and Karaskara beeja according to the methods mentioned in Rasasastra books. Parada was extracted from Hingula by Ordhwapaathana vidhi. It was then triturated with Shuddha Gandhaka to get Kajjali. Fine powders of other drugs were mixed with Kajjali and rolled into pills with Honey. Study observed the physicochemical parameters of individual drugs and validated the Gulika by HPTLC method. Analysis of Kajjali was done using XRD so as to prove the complete formation of Kajjali. Pharmaceutical standardization helps in reproducibility of drug paving way for more studies on toxicity and efficacy of drug.
Yönetim Alanında Fenomenoloji Kavramının Görsel Haritalama Tekniğiyle Bibliyometrik Analizi
Authors: SAVAŞ Yasemin
Published: April 2023

Yönetim bilimi, insan odaklıdır ve yönetim alanını içeren birçok konu tıpkı insan hayatında olduğu gibi istatistiksel olarak irdelenemeyen oluşumları barındırır. Bu doğrultuda fenomenoloji kavramı yönetim alanında algısal bakış açısıyla anlamlandırmaya rehberlik eder. Fenomenoloji, bir felsefe, bir araştırma paradigması, bir metodoloji olarak tanımlanmış ve nitel araştırma ile eş tutulmuş bir terimdir. Araştırmanın amacı, fenomenolojiyi felsefi bir kavram olarak yönetim alanında yapılmış çalışmalar odağında yapılan bilimsel yayınların içerik analizini yaparak ilgili literatüre katkı sağlamaktır. Bu doğrultuda, araştırmada öncelikle Web of Science veri tabanı kullanılarak fenomenoloji konusunda yapılan 398 bilimsel yayın bibliyometrik analiz yöntemi ile irdelenmiş, ardından elde edilen veriler VOSviewer yazılım programı kullanılarak görselleştirilmiştir. Bilimsel yayınlar üzerinde atıf analizi, anahtar kelime, ortak yazar atıf analizi gibi bibliyometrik yöntemler kullanılmıştır. Bibliyometrik yöntemleri kullanarak, alanın dinamiklerine ilişkin kapsamlı bir görüş sunarak ve temel çalışmaları, ülkeleri, dergileri ve yazarları belirleyerek yönetim alanında fenomenoloji kavramına ilişkin literatürün gelişimi haritalandırılmıştır. Analiz sonucunda ulaşılan bulguların yönetim alanında fenomenoloji konusunda gelecekteki çalışmalara kaynak sağlayacağı düşünülmektedir.
Impeachment Procedures in Nigeria and the United States of America: A Comparative Analysis
Authors:   Department of Public Law, Faculty of Law, Ekiti State University, Ado-Ekiti, Nigeria., Akpambang, Ph.D Enobong Mbang , Ojo, Ph.D Aderonke Abimbola ,   Department of Private and Property Law, Faculty of Law, Ekiti State University, Ado-Ekiti, Nigeria.
Published: April 2023

Under a presidential system of government, executive powers are vested on the President at the federal level and the Governor at the state or sub-national level. Given the wide powers constitutionally conferred on the executive arm of government along with immunity from civil or criminal proceedings, the instrument of impeachment is incorporated into the Constitution to act as a check and balance against authoritarianism or misuse of official power. The foremost objective of this article is to comparatively scrutinise the modus operandi for impeachment of the President or Governor in Nigeria and the United States of America (USA); the USA impeachment mechanism would be limited to the federal impeachment process of the President and the Vice President. The article employed desk-based or doctrinal and comparative research methods by placing reliance on both primary and secondary sources of information. The sources of information were analysed and inferences obtained were presented descriptively. The article revealed inter alia, that though Nigeria and USA practice presidential system of government as well as operate a federal system, yet, there are some procedural parallels and dissimilarities in their respective impeachment procedures. A case in point is that in the USA, an impeached official cannot subsequently be granted pardon by the President whereas in Nigeria, there is no constitutional clause barring the President or the Governor from granting pardon to a convicted elected executive office holder. The authors therefore, recommended inter alia, that a constitutional amendment should be introduced to sections 175 and 212 of the 1999 Constitution of the Federal Republic of Nigeria (1999 CFRN) with the goal of outlawing the President or Governor from granting pardon to an impeached official, as obtainable in the USA.
The Medical Rehabilitation of Overactive Bladder after Transurethral Resection of the Prostate: A Case Report
Authors:   Department of Medical and Rehabilitation, Muhammadiyah Siti Aminah Hospital Brebes, Indonesia, Mulyani Nia Tri , Irmayanti Wiwiet ,   Department of Medical and Rehabilitation, Muhammadiyah Siti Aminah Hospital Brebes, Indonesia, Kurniasari Dian ,   Department of Urology, Muhammadiyah Siti Aminah Hospital Brebes, Indonesia
Published: April 2023

Introduction: Overactive bladder is a syndrome of increased urinary frequency and nocturia with or without incontinence in absence of obvious pathology. Transcutaneous Tibial Nerve Stimulation (TTNS) is one of the neuromodulation used to treat overactive bladder. We report the medical rehabilitation program in overactive bladder post-Transurethral Resection of The Prostate (TURP). The medical rehabilitation program consisted of pelvic floor muscle exercise and TTNS that may reduce the overactive bladder symptoms. This study aims to determine whether TTNS and pelvic floor muscle exercise will reduce overactive bladder symptoms after TURP. Case Presentation: a 40-year-old Asian man who developed overactive bladder symptoms after TURP had the medical rehabilitation program consisting of pelvic floor muscle exercise and TTNS. The pelvic floor exercise was given twice a day and TTNS was given twice a week for 12 cycles and repeated for 12 cycles. He was followed up by Over Active Bladder Symptoms Score (OABSS) to assess the severity of symptoms. Conclusion: The medical program rehabilitation that consisted of pelvic floor muscle exercise and TTNS reduced 50% in the severity of overactive bladder symptoms after TURP. No complications have been reported. Need further research to know the definitive result.
The Impact of Total Caloric and Macronutrient Consumption on Strength and Power During an Off-Season Training Program in Collegiate Volleyball Players
Authors: Figueroa Yvette , Perry Arlette
Published: April 2023

Adequate caloric and carbohydrate intakes are necessary for positive adaptations to exercise training, yet there is limited research examining dietary intake in relation to strength and power in female athletes. The purpose of this study was to determine 1) whether there were significant changes in weekly total caloric and macronutrient consumption, strength, and power, and 2) whether total caloric and macronutrient consumption significantly and positively contributed to changes in strength and power across a controlled eight-week, off-season resistance training program. Eleven collegiate-level female volleyball players were examined on macronutrient consumption, strength, and power at two-week intervals using three-day food logs, 3-repetition maximum bench press and back squat, and vertical jump, respectively. Five assessments were conducted on each subject. Alpha level was set at r < 0.05. Paired samples t-tests showed improvements in body mass index, lean body mass, percent body fat, and lower body strength and power following eight weeks of training (r < .05) despite no significant changes in total calories or macronutrients. Results of a weighted regression analysis indicated that both total caloric consumption and carbohydrate intake influenced lower body power after training (r < .05). However, nutrient intake did not impact strength or power at any of the two-week intervals. We believe these findings are related to the neuromuscular adaptations that occur early in training. A longer resistance training program resulting in gains in muscle cross-sectional area (CSA) may be necessary to further examine the contribution of calories and macronutrients to performance-related variables.
Autoimmune Hemolytic Anemia, Amoebic Dysentery, And Intracranial Hemorrhage as Rare Manifestations of Smoldering Multiple Myeloma: A Case Report
Authors:   Internal Medicine Resident - Dr. Soetomo Hospital – Medical Faculty of Airlangga University Surabaya Indonesia, Kusumawindani Dananti
Published: April 2023

Background: Smoldering multiple myeloma (SMM) is in asymptomatic stages before overt multiple myeloma (MM) but it also has an increased risk of thrombosis, infection, autoimmune, and hemorrhage. SMM is usually recognized coincidentally during the workup of a variety of symptoms.
COVID-19 and autoimmune rheumatic diseases
Authors:   Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia, Putri Ayu Arifta , Awalia Awalia , Rusli Musofa
Published: April 2023

Background: Coronavirus disease 2019 (COVID-19) was declared a pandemic since it rapidly spread worldwide. COVID-19 has various manifestations, ranging from asymptomatic to life-threatening conditions. During the pandemic, patients with autoimmune rheumatic diseases (ARD) were included in the population at risk. In addition, the use of immunosuppressants or disease-modifying antirheumatic drugs (DMARDs) was considered to increase the susceptibility to infection. Studies have reported that COVID-19 and ARD have similarities in their clinical findings and immune responses. This study aims to understand the profile of patients with ARD infected with COVID-19 at Dr. Soetomo Hospital in 2020–2022.
Análise de elementos transponíveis em Hemileia vastatrix e Coffea spp.
Authors:   , Silva Lucas Fagundes da
Published: April 2023

A ferrugem do cafeeiro é causada pelo fungo Hemileia vastatrix Berk. & Broome, um parasita obrigatório que infecta folhas de plantas do gênero botânico Coffea. Entre as espécies cultivadas deste gênero, Coffea arabica é a mais suscetível. A desfolha precoce pode levar à morte de ramos, seguido de perdas da produtividade no ano subsequente. Os danos podem alcançar índices de 50% quando as condições são favoráveis. Há um consenso que existe grande variabilidade genética na população de H. vastatrix e o surgimento de novas raças são um grande desafio para o manejo da doença. A raça II de H. vastatrix é a mais prevalente e a raça XXXIII suplantou a resistência de algumas cultivares comerciais de C. canephora no Brasil. No entanto, como o ciclo sexual ainda é parcialmente descrito, não são claros quais são mecanismos-chave de variabilidade genética ligados ao surgimento de raças em H. vastatrix. Nesse contexto, os elementos transponíveis (ETs) podem ser uma abordagem promissora, porém, pouco explorada nos estudos que visam a compreender a variabilidade genética em raças de H. vastatrix. Este trabalho teve como objetivo verificar o impacto de retrotransposons e elementos transponíveis de DNA nos genomas de H. vastatrix, C. arabica, C. canephora e C. eugenioides. Foram desenvolvidos scripts de bioinformáticas para identificação, caracterização e analise da divergência genética. No capitulo I, foram identificados ETs expressos nas interações de compatibilidade entre H. vastratrix e o cafeeiro. No capítulo II, as populações dos ETs foram estruturadas de acordo com as espécies de café analisadas. No capítulo III, genótipos de café arábica foram agrupadas em função do padrão de resistência às raças II e XXXIII de H. vastatrix. Este trabalho relata novos ETs e apresenta novas informações sobre seus os impactos na coevolução entre o H. vastatrix e cafeeiro. Palavras-chave: Transcriptoma. Hemileia. Coffea. Transposons.
Práticas de avaliação formativa no contexto do programa residência pedagógica
Authors:   , Barbosa Luís Rafael
Published: April 2023

Este trabalho de mestrado profissional surgiu como alinhamento entre a vivência do autor e a necessidade de se criar um produto educacional que auxiliasse educadores em sua prática pedagógica, com a intenção de promover transformações reais. Assim, se consolidou o tema Avaliação da Aprendizagem, nem sempre aprofundado na formação inicial de professores. E se questionou: “Como um módulo educativo sobre práticas formativas de avaliação no Programa Residência Pedagógica (PRP) impacta na formação de professores de Química e Física?” A ideia foi promover três encontros virtuais, ajustados devido a pandemia da COVID-19, com docentes em formação do PRP junto com entrevistas e questionários. O módulo foi planejado a partir da Taxonomia de Bloom, objetivando a construção de habilidades em uma ordem coerente de complexidade, partindo das mais simples cognitivamente, como lembrar e entender, por exemplo, até a mais avançada, de criar. Além disso, a pesquisa perseguiu confirmar a efetividade do módulo na perspectiva dos participantes (plano fenomenológico) em uma análise qualitativa aplicada. Na análise dos resultados, estes indicaram evolução positiva dos participantes quanto aos conhecimentos avaliativos tanto no campo teórico quanto empírico, sinalizando ainda visões mais profundas e reais sobre temas sensíveis como a utilização de notas, o papel da comunidade escolar e os índices de classificação educacional como o IDEB, por exemplo. Os participantes avaliaram a experiência do módulo como significativa, discorrendo mudanças comportamentais, apesar da restrição imposta pela pandemia. Os indicadores utilizados apontaram um alto grau de qualidade e também de importância para a formação docente. Em suma, os conhecimentos construídos e as significativas experiências vivenciadas serviram para a criação do produto educacional, uma cartilha intencionada no suporte aos professores que desejam implementar o processo formativo de avaliação em suas práticas de ensino-aprendizagem. Palavras-chave: Avaliação Formativa. Avaliação da Aprendizagem. Taxonomia de Bloom. Residência Pedagógica. Produto Educacional.
A Case of Neck Avm Supplied By Arteria Lusoria
Authors:   Department of Medicine, Shah Alam Hospital, Malaysia, M Shanthi , N Ruchi ,   Department of Clinical Research, Malaysia, A Saiful ,   Department of Medicine, Shah Alam Hospital, Malaysia
Published: April 2023

Classification of Vascular malformation is based on ISSVA classification. Here is a brief outline of vascular malformation classification.
Klebsiella Variicola: Bir Bakteriyemi Olgusu ile Literatürün Değerlendirmesi
Authors: KUVVETLİIŞIK Şeyma , KARACAER Zehra , BULUT Cemal
Published: April 2023

Bir üçüncü basamak hastanesine ateş ile başvuran hasta enfeksiyon kaynağı araştırılmak üzere takip edildi. Hastada toplum kaynaklı bir enfeksiyon kaynağı görüldü, bakteriyemide etken olarak Klebsiella variicola saptandı. K. variicola sporadik enfeksiyonlara ya da salgınlara yol açabilmektedir. Olguda sunduğumuz izolat duyarlı bir suş olmasına rağmen dirençli suşların gelişebildiği, bunun ilerleyen dönemlerde bir sorun teşkil edebileceği düşünülmektedir. Bu durumda etkenin sağlıklı tespit edilmesi ve tanımlanmasında kolay uygulanabilecek sistemlere ihtiyaç duyulmaktadır.
Üretrada Papillom Benzeri Görünümde Prostat Kanseri Düşünmeli miyiz?
Authors: KÜÇÜKYANGÖZ Mustafa , SOGUTDELEN Emrullah , ÜYETÜRK Uğur
Published: April 2023

Üretranın skuamöz hücreli papillomu; nadir görülen, dizüri gibi alt üriner septomlarla bulgu veren, benign proliferatif skuamöz lezyondur. Kesin tanı ve tedavi için cerrahi eksizyon ve patolojik inceleme gerekmektedir. Bu olgu sunumunda makroskopik hematüri nedeniyle başvuran 76 yaşında hastanın sistoüretroskopik incelemesinde üretrada boylu boyunca gözlenen birçok papillomun transüretral eksizyonu sonucu yapılan patolojik incelemesinde tümöral lezyonun prostat kanserine bağlı metastazlar olduğu saptandı. Literatürde malign üretral lezyonların sıklıkla mesane kanserine bağlı metastazlar olduğu görülmüştür. Bu nedenle nadir görülen bu vakayı sunmayı amaçladık.
PERAN KOMUNIKASI PEMERINTAH ACEH TIMUR MEMPERKENALKAN DESTINASI WISATA HALAL
Authors: Samsuar  , Mukhlis Muhammad , Maulana Sirajul
Published: April 2023

This article researches the East Aceh regency government's effort to give the concept and persuade society around tourism destination places related to the halal tourism concept raised by the government. This research uses a constructive paradigm and also a qualitative approach. Maximum variation technique is used in collecting data, consideration of large area and diversity of people to be involved; all of these are the key factor in this case. Data collection is sliced using the Diffusion Theory cutter by Gabriel Tarde. The result of this research shows that many communication available ways are used in making an effort by the East Aceh government, including by making an interpersonal approach with the informal leader and leading religious figures give impact toward implementing halal tourism in East Aceh regency.
DAKWAH PENANAMAN NILAI-NILAI KARAKTER DAN RELEVANSINYA TERHADAP PENANGKALAN RADIKALISME PADA KALANGAN SANTRI DI KABUPATEN ACEH JAYA
Authors: Paisal Jon , Mukhlizar
Published: April 2023

In this technological era, it is effortless to be exposed to radicalism and terrorism. Moreover, Aceh, a former conflict area, is considered very worthy of being declared violent by certain groups. Moreover, this understanding will enter the dayah environment, affecting the students. The research entitled Da'wah is about cultivating character values ​​and their relevance to preventing radicalism among students in Aceh Jaya Regency. Using qualitative research methods, data were collected through interviews, documentation and observations in several dayahs in Aceh Jaya District. The study results reveal that the views of the dayah ulama in Aceh Jaya reject radicalism and terrorism. To prevent the exposure of radicalism among the santri, the dayah ulama in Aceh Jaya district carried out da'wah to instill character values ​​in students through the exemplary attitude of the dayah ulama. Encourage students to get used to memorizing the Qur'an and recitation of the yellow book. Moreover, the cultivation of character values ​​through activities to commemorate significant holidays.
A Study on the Influence of Product Characteristics on Consumer’s Purchasing Intention: A Case Study of Mixue Ice Cream & Tea
Authors:   The East Asian Trade Association, Li Zesheng , Ni Na
Published: April 2023

Purpose - With the improvement of people’s quality of life, tea drinks have become increasingly integrated into consumers’ daily routines. However, due to the prevalence of commodity homogenization, various competitive brands have emerged in the leisure industry, such as Mixue Ice Cream & Tea, Coco, Auntie in Shanghai, Dieting, and others, which has resulted in mounting competitive pressure within the industry.
Design/Methodology/Approach - In order to enhance the competitiveness of Mixue Ice Cream & Tea and increase market sales by improving consumer repurchase frequency, this study conducts an in-depth analysis of the product characteristics of Mixue Ice Cream & Tea and examines their relationship with consumer behavior.
Findings - Based on the research objectives described above, this paper conducts a questionnaire survey on consumers and target Mixue Ice Cream & Tea consumers to analyze the relationship between product characteristics and consumer behavior. The current situation of the leisure beverage market is also analyzed, and statistical analysis is performed on the collected data. The results indicate that product characteristics positively impact customer satisfaction and purchase intention.
Research Implications - To improve the sales volume and market share of Mixue Ice Cream & Tea, this study incorporates the experimental results to provide marketing recommendations and corresponding strategies for Mixue Ice Cream & Tea enterprises. In addition, the findings will provide important guidance for developing Mixue Ice Cream & Tea enterprises in the leisure beverage market.
Evaluating the efficiency of public relations programs in the Administration
Authors: Rus Mihaela , Tasențe Tănase , Burcă Anca Alexandra
Published: April 2023

The trust capital of the population in public institutions can be gained by developing and implementing social responsibility campaigns with specialized NGOs or sponsors from the private sector. These campaigns are intended to take into account the interest of society, and their main purpose is to improve the quality of life of each citizen, as well as for the local community and society in general. The social responsibility campaign is one of the most current management strategies in which companies try to create a positive impact on society while carrying out their activity, and their evaluation is essential to measure the impact that these campaigns have generated among citizens, in particular, but also in society in general.
Institutional communication models and strategies adapted to New Media
Authors: Nicolae (Halep) Carmen-Georgiana , Rus Mihaela , Tasențe Tănase
Published: April 2023

New media has revolutionized the way that organizations communicate with their stakeholders. The traditional models of communication, such as mass communication, word of mouth, and direct mail, are no longer enough to reach today's audiences. In order to be successful in this new media environment, organizations must adapt their communication models and strategies to take advantage of the opportunities that new media provides. This paper will explore the various models and strategies that organizations can use to effectively communicate in the new media environment. The first step in adapting communication models to new media is to understand the various ways that people consume and interact with digital content. There are three main models for communicating with an audience online: broadcast, engagement, and relationships. Broadcast communication is a one-way communication model that is used to reach a large audience with a single message. This model is typically used when an organization has limited resources or time and needs to quickly disseminate information to a large group of people. Engagement communication is a two-way communication model that encourages people to interact with content by providing feedback, comments, and opinions. This model is best used when an organization wants to build relationships with its audience and create a dialogue. Finally, relationship communication is an ongoing communication model that focuses on building long-term relationships with stakeholders by providing timely, relevant, and personalized content. This model is best used when an organization wants to establish loyalty and trust with its target audience.
Social Media communication strategy within the municipalities of the Republic of Moldova
Authors: Carapascal Carolina , Tasențe Tănase
Published: April 2023

Communication through online social networks has become an essential part of the public administration in the Republic of Moldova. The public administration of the Republic of Moldova uses online social networks to promote development initiatives and inform the public about them. They have become an important tool for communicating with the public and for providing information about public services. They also allow the public administration to use social network platforms to launch information campaigns on other public development programs. These social networks are also used to monitor and respond to public comments and to answer questions about public services. This helps to build trust and transparency in the public administration. In addition, online social networks can help promote and develop partnerships with non-governmental organizations and other entities, so that better public services can be offered. The public administration of the Republic of Moldova uses social networks to support the decision-making process and to provide information about the implementation process. They can also be used to inform the public about development programs and to provide information about different programs aimed at people from vulnerable groups.
Urban Forestry: Growing a Fuller Canopy
Authors: Stern Ava , Elszasz Hayley
Published: April 2023

This paper reports on the discipline of urban forestry (UF), including an assessment of the current state of UF globally and in Oakland, California as the primary case study. It identifies and analyzes prominent international, national, state, and municipal bodies and presents an original framework for UF success. Oakland is assessed against this framework. The paper concludes with suggestions for how UF can progress in the future. The findings are informed by primary and secondary research, including interviews with government and community actors, analysis of papers written by established bodies like the United Nations, and the author’s personal experience participating in grassroots UF efforts in Oakland.

 

The paper asserts that urban forestry is at an inflection point. It is quickly gaining worldwide prominence for its potential to address climate change and improve a multitude of issues facing urban life. The case of Oakland reveals that the city is also hitting an exciting moment with the creation of an Urban Forest Master Plan that is set to dictate UF goals for the next fifty years. While there have been challenges in maintaining and expanding tree canopy in cities like Oakland, the prospect of a fuller canopy seems achievable and imperative.
Evaluating the Effectiveness of Life Without Parole as an Alternative to the Death Penalty
Authors: Tsai Justin , Chen Pei-Ching
Published: April 2023

Death penalty in the United States has been steadily replaced by life without the possibility of parole (LWOP) sentences since 2001. As of July 2021, the number of people on death row imprisoned in state, federal, or military prisons was down to a thirty-year low, which translated to a 33% decrease since its peak in July 2001. On the other hand, the number of people serving LWOP increased by 66% since 2003. This paper reviews current academic literature to compare the pros and cons of LWOP and death penalty from financial and psychological points of view in response to the question of whether LWOP is a more effective alternative to the death penalty in the United States. From a total cost perspective, LWOP is less costly to execute than that of a death sentence. Psychologically speaking, LWOP may be more satisfactory for both families of the victims and defendants. However, while LWOP has been regarded by many as more humane, its effectiveness has been degraded by harsh policies in the 1980s and 1990, which have resulted in prison overcrowding and the United States having the highest prison incarnation rate in the world. In addition, diminishing rights is a common issue experienced by LWOP prisoners. Therefore, the author concludes that while LWOP has strengths over the death penalty, its ultimate effectiveness remains in question.
Transcutaneous Electrical Nerve Stimulation (TENS) as an Alternative Perioperative Pain Treatment
Authors: Hong Shannon , Huang Yongmei
Published: April 2023

Perioperative pain is a significant medical issue affecting over 80% of surgical patients annually. Currently, perioperative pain is one of the leading causes of a decreased quality of life. The most common treatments for perioperative pain, such as opioids and non-steroidal anti-inflammatory drugs (NSAIDs), have many serious adverse effects, especially when used long-term. As a result, clinicians must find and assess some alternative treatments that will reduce the perioperative pain level and harm their patients the least. Recently, non-pharmacological treatments have been gaining popularity for their pain-relieving abilities with few side effects. Transcutaneous electrical nerve stimulation (TENS) has shown the potential to lower the number of analgesics consumed by surgical patients and to be an effective non-pharmacological treatment for perioperative pain with no severe side effects. However, previous studies show that there is not much knowledge of TENS and its consequences. Overall, the usage of transcutaneous electrical nerve stimulation during the perioperative experience is understudied and underrepresented. Thus, this report aims to explain further and explore the role of TENS as an alternative treatment for perioperative pain.
Probability of life on Mars utilizing biosignatures
Authors: Krishna Divya , Kethar Jothsna
Published: April 2023

Biosignatures are key pieces of evidence of life on other planets, in this research paper we will be focusing specifically on Mars. This paper compiles research from other papers and highlights probabilities and improbabilities of life from data on Mars and terrestrial analogs on Earth. Hydrated areas likely to have liquid water exhibit a correlation with life as liquid water is commonly thought to be the “key” to an organism's survival. Analogs on Earth may also simulate similar conditions to that of Mars and illustrate various life forms that have inhabited these areas. Sources of energy observed in these analogs as well as Mars can be conducive to life. However, just because an environment is habitable does not mean life inhabited it. The paper also compares false biosignatures which may be misleading about the presence of life. The importance of this paper is to address the ambiguity and presence of microbial life on Mars.
Modeling piezoelectricity’s impact on environmental parameters with real-life applications
Authors: Seshadri Sriram , Sayyad Armaan
Published: April 2023

With a rapid increase in the global human population in recent years, the Earth is in dire need of alternative energy sources. The objective of this paper is to assess the feasibility of implementing piezoelectricity as a primary source of renewable energy. Specifically, this paper looks at its consequent impact if introduced in 3 fundamental areas of implementation: bus tires, train tracks and railway stations. Each of these areas provide input elements at scale to generate electricity and are simple to implement, maintain and measure through government support.  This paper limits the data to the city of Cairo, Egypt. Being low cost as well, the three areas come close to an ideal situation from an economic standpoint. Predictive algorithms and existing data are used to evaluate the consequent change in global green-house emissions and other environmental parameters, had piezoelectricity been previously implemented. The results of the equations show that there would be improved environmental conditions - thus, a net positive impact - that switching to piezoelectricity would have had on the atmosphere and environment. The predictions stay true, provided that the efficiency of the piezoelectric crystal remains constant- an outcome which serves to boost output and lower greenhouse emissions
Early Testing of Alzheimer's using Biomarkers
Authors: Utal Kiranpreet , Kethar Jothsna
Published: April 2023

This paper covers the biomarkers that can be used to test for and diagnose Alzheimer’s Disease. This is important due to the large number of people globally who are suffering from this disease. Two types of biomarker origins were explored here: blood and cerebrospinal fluid. Currently, the standard for testing Alzheimer’s biomarkers is through the use of cerebrospinal fluid collection. These are the biomarkers that have been thoroughly tested and accepted as accurate and reliable, such as Aβ (1-42) and Tau-related proteins. There are also possible biomarkers found in blood. These include Aβ-related proteins, Tau-related enzymes, as well as inflammatory markers. It has been concluded that the most reliable source of biomarker testing is cerebrospinal fluid. However, there have been significant advancements in studies showing that the use of blood may one day become a very real possibility for routine testing. Until then, it is best to keep a healthy lifestyle that will aid in the prevention of this disease.
Sports Injuries and Their Lingering Long-Term Effects: Proposing the Addition of Injury Prevention Programs within Athletics
Authors: Theobald Abigail , Dennis Justin
Published: April 2023

The present review article analyzed the long term effects of sports injuries, whether adequate measures were already being taken to prevent serious injury within athletics, and what new methods could be implemented to reduce the high prevalence of such injuries. Athletes are faced with an increased pressure to perform due to the societal expectations of achieving success at an expedited rate. This pressure combined with the lack of preventative measures and education within athletics causes both acute and chronic injuries. This article examines how these injuries can not only have devastating short-term effects on the athlete, but can also cause long-term effects that impact the remainder of the athlete’s life. Some athletes are forced to drop out of participation, have to live with constant pain, and/or are unable to partake in physical activity later in life. Based upon the reviewed research, this is becoming a widespread issue within and beyond the public school system, with many institutions choosing not to implement preventative measures for their athletes.
Current Advancements in the Treatment of Alzheimer’s Disease
Authors: Ajith Varun , Kalam Ali
Published: April 2023

Alzheimer’s disease (AD) has been the most prevalent form of dementia since its initial discovery in the 20th century. Despite the technological innovation and groundbreaking research that has been developed and completed, there hasn’t been any reported fix that can cure its symptoms, presenting a need to find more effective therapeutic solutions. From targeting amyloid plaques to the tau regions of neurons in the brain, there have been several attractive targets that may hold the solution to curing AD. With many different experimental drugs and therapies being tested everyday, the purpose of this literature review is to summarize what some of the various treatments entail with regards to the neurobiology behind Alzheimer’s, how they affect those selected regions, as well as potential future therapeutic solutions for this disease.
Permanent Effect of SARS-CoV-2 on the Heart, Post Recovery
Authors: Tej Siraj , Appavu Rajagopal
Published: April 2023

COVID-19 is an infectious disease caused by the SARS-CoV-2 virus. Since December 2019, when the initial outbreak of COVID-19 occurred in China, a series of effective preventive control and medical treatment measures have been implemented, and have brought the pandemic under control to a certain extent. Most people infected with the virus will experience mild to moderate respiratory illness and recover without requiring special treatment. However, some will become seriously ill and require medical attention. A growing number of studies suggest many COVID-19 survivors experience some type of heart damage, even if they didn't have underlying heart disease and weren't sick enough to be hospitalized. Recent statistics estimate there being around 523.2 million cases of cardiovascular disease in the world, which represents the large population that this side effect or aftereffect potentially encompasses. According to research, there are structural changes in that take place when COVID enters a person’s body. In this case, the effect on the heart is relatively unknown or unproven. However, scientists and doctors have reported a couple of observations. First, the weight of the heart increased slightly after patients recovered from COVID. Second, Signs of cardiac enlargement and right ventricular dilatation were also noted. Under microscopic attention, scattered individual cardiomyocyte necrosis was visible as well. This paper will outline specific effects of COVID on the heart.
Using Machine Learning Regressors for the Discovery of Culex Mosquito Habitats and Breeding Patterns in Washington D.C.
Authors: Xia Iona , Singirikonda Neha , Hellman Landon , Watson Jasmine , Hanna Marvel , Low Russanne
Published: April 2023

Culex mosquitoes pose a significant threat to humans and other species due to their ability to carry deadly viruses such as the West Nile and Zika. Washington D.C., in particular, has a humid subtropical climate that is ideal as a habitat for mosquito breeding. Thus, tracking mosquitoes’ habitats and breeding patterns in Washington D.C. is crucial for addressing local public health concerns. Although fieldwork techniques have improved over the years, monitoring and analyzing mosquitoes is difficult, dangerous, and time-consuming. In this work, we propose a solution by creating a Culex mosquito abundance predictor using machine learning techniques to determine under which conditions Culex mosquitoes thrive and reproduce. We used four environmental variables to conduct this experiment: precipitation, specific humidity, enhanced vegetation index (EVI), and surface skin temperature. We obtained sample data of these variables in the Washington D.C. areas from the NASA Giovanni Earth Science Data system, as well as mosquito abundance data collected by the D.C. government. Using these data, we created and compared four machine learning regression models: Random Forest, Decision Tree, Support Vector Machine, and Multi-Layer Perceptron. We searched for the optimal configurations for each model to get the best fitting possible. Random Forest Regressor produced the most accurate prediction of mosquito abundance in an area with the four environment variables, achieving a mean average error of 3.3. EVI was the most significant factor in determining mosquito abundance. Models and findings from this research can be utilized by public health programs for mosquito-related disease observations and predictions.
Treatments of Alzheimer’s Disease: A Review
Authors: Zhu Alex , Sahai Sharifa
Published: April 2023

Alzheimer’s Disease (AD) affects about 24 million people worldwide and costs Americans billions of dollars every year.1 With the prevalence of AD, treatments are needed to combat the disease and reduce its effect. In the past, cholinesterase inhibitors were used to treat the symptoms of the disease. In recent years, however, a new type of drug, monoclonal antibody, has been used for the treatment of AD. The purpose of this paper is to review the old and new Alzheimer’s treatment through the lens of affordability and accessibility, and provide insight into the future of the treatment options. In the end, innovative treatments such as vaccines and targeting different mechanisms of action are the next step in Alzheimer’s treatment. Access to these treatments should be more readily available and affordable to low-income families. To support this, the FDA should modify its accelerated approval program to reward rigorous scientific research.
Connecting Hearing Loss: Causes, Treatments, and Prevention
Authors: Challa Bhavana , Kethar Jothsna
Published: April 2023

Everyone has five senses: touch, taste, smell, sight, and hearing. Each of these plays a vital role in one's life. But what happens when you don't have one of these and are forced to live with it?  Hearing loss is a condition that affects one of these five senses: hearing. Those affected by this condition lose their hearing. It may be a partial loss or complete loss but they cannot hear as one normally should. This condition is quickly growing to be common around the globe affecting a wide variety of people. What makes these conditions so unique is that there is a multitude of causes for them. This paper focuses on some of these causes to find a connection. It was found that one connection between all of these causes is that they are a result of some sort of physical damage or injury to the ear. But this injury’s location and specifications are different in each case yet the result is also hearing loss. Furthermore, this paper offers solutions and prevention for some of the different cases of hearing loss that can be encountered; thereby preparing persons to avoid this condition.
Machine Learning in Neuroimaging for Diagnosis of Major Depressive Disorder
Authors: Watanathawornwong Matchima
Published: April 2023

Is machine learning an effective diagnostic tool to identify the presence of major depressive disorder in a patient? Major depressive disorder (MDD) is a common mood disorder, distinguished by prolong emotional distress and dysfunction in normal activities, yet its current diagnosis still depends on subjective interpretation of clinical interviews and self-reported symptoms. Not only are these prevalent methods susceptible to inconsistent diagnoses, the lack of clear boundaries in present diagnostic criteria to evaluate MDD also further magnifies the need for objective diagnostic tools in clinical environment. One of those methods explored by psychologists is the application of machine learning in neuroimaging techniques. Due to its analytical prowess, machine learning has become popular in psychological research to understand and discover biomarkers in illnesses. This literature review aims to evaluate the effectiveness of different machine learning models and neuroimaging in classifying MDD patients before discussing some of the major setbacks faced by researchers and the suggested solutions for overcoming these barriers to clinical application.
Strategies Against Future Pandemics: An Analytical Overview of COVID-19 Response
Authors: Meng Zimiao , Asmis Reto , Crowder Mark
Published: April 2023

COVID-19, or Coronavirus Disease of 2019, is caused by the severe acute respiratory syndrome virus 2 (SARS-CoV-2). Due to its highly infectious nature and high mortality rate, the effects of COVID-19 have taken social and economic tolls on countries across the globe. The impactful and devastating pandemic led to more than 600 million cases and over 6.5 million deaths worldwide, according to the World Health Organization. The purpose of this proposal is to 1) address the weaknesses in COVID-19 policy responses and 2) propose additional measures to both prepare for and respond to the next COVID pandemic. When another pandemic occurs, the government should focus vast amounts of resources on developing an effective vaccine and test while arranging personnel to carry out testing and contact tracing. Mandates such as mask-wearing and physical distancing will be implemented to help slow down the infection. In addition, the government needs to ensure that the public is receiving reliable and credible information about the pandemic, as well as personal hygiene information to improve adherence to the policies. Then, if the healthcare system is overwhelmed and the spread is out of control, lockdown should be considered after evaluating all the potential negative effects. Although the COVID-19 pandemic’s severity has seemed to wane over time, staying cautious will help the country to be ready for similar situations.
ANALISIS FAKTOR- FAKTOR YANG MEMPENGARUHI KINERJA KARYAWAN PADA KSP SUMBER JAYA LAMONGAN
Authors: Ahmadi Edy Anas , Setiawan Edial Nanang
Published: April 2023

The aims of the study is determine how many factors that influence to the employe factor mainly factor of leadership, organizational culture, competence and motivation on employee performance in KSP Sumber Jaya Lamongan. The population in this study are employees at KSP Sumber Jaya Lamongan while the sample population were all employees of cooperatives totaling 30 people, sampling techniques is the saturation sampling because the entire population is used as a sample and also less than 30 people.To obtain the necessary data the authors used data collection techniques such as interviews and questionnaires, techniqueanalysis used in this research is descriptive method.

From the discussion concluded that KSP Sumber Jaya Lamongan is a savings and credit cooperatives in which variable competence and work motivation are effected significsnt partially on the performance of employees in KSP Sumber Jaya Lamongan while the leadership and organizational culture are not effected significant partially on performance employeer of at KSP Sumber Jaya Lamongan.

So the contribution of variable influence leadership competencies organizational culture and work motivation on employee performance in KSP Sumber Jaya Lamongan amounted to 88.3%, while the remaining 11.7% is influenced by other variables that not examined
PENERAPAN BAURAN PEMASARAN DALAM USAHA MENINGKATKAN VOLUME PENJUALAN PADA CV. SURYA GEMILANG MOTOR LAMONGAN
Authors: Ahmadi Edy Anas
Published: April 2023

Application Marketing Mix In The Business Volume Increase Sales By Surya Gemilang Motor Dealer Lamongan. In the business world, where human knowledge is increasingly pushing their increasingly sharp competition, that requires every company to more actively market their goods or their products in the market. Marketing management should be able to create a satisfactory service to customers and at the same time can also compete aktif.Tujuan study was to determine the role of marketing mix ie product, price, promotion, distribution in increasing the volume of motorcycle sales in CV.SuryaGemilang Motor this Lamongan.penelitian using multiple regression analysis and hypothesis testing (test T and F) with Likert scale. The population was 1,299 consumers with a sample of 93 responden.Berdasarkan methods nonpurposivesampling.Hasil simultaneous testing showed a variable product, price, promotion and distribution of jointly significant effect on the sales volume in CV.SuryaGemilang Motor Lamongan with Fhitung 89.839 .with using partial test shows the product variable (X1) of 1,489, the price (X2) is 2,626, promotions (X3) of 2,511 and distribution (X4) of 1.345. Variable price (X2) and promotion (X3) had a partial effect on the volume of sales, product variables (X1) and distribution (X4) does not have a partial effect on the volume penjualan.Dan price variable (X2) were dominant influence on the sales volume of bicycles motorcycle.