bluuebunny/crossref_metadata_2025 huggingface dataset:
Perbedaan Jumlah Bakteri Orofaring Pada Tindakan Oral Hygiene Menggunakan Chlorhexidine Dan Povidone Iodine Pada Penderita Dengan Ventilator Mekanik
Authors: Helmi Mochamat , Arifin Johan , Pujo Jati Listiyanto
Published: December 2022

Latar belakang: Antiseptik oral hygiene merupakan salah satu cara yang dapat menurunkan insiden ventilator associated pneumonia (VAP). Chlorhexidine dan povidone iodine merupakan antiseptik yang mampu menurunkan jumlah bakteri pada proses dekontaminasi orofaring.Tujuan: Untuk mengetahui adanya perbedaan penurunan jumlah bakteri orofaring pada tindakan oral hygiene dengan chlorhexidine 0.2% dan povidone iodine 1% pada penderita dengan ventilator mekanik.Metode : Merupakan penelitian Randomized clinical control trial pada 30 penderita dengan ventilator mekanik. Penderita dibagi menjadi 2 kelompok (n=15), kelompok 1 menggunakan chlorhexidine 0,2% dan kelompok 2 menggunakan povidone iodine 1%. Masing-masing kelompok diberikan oral hygiene tiap 12 jam selama 48 jam. Tiap kelompok diambil sekret dari orofaring sebelum dan setelah perlakuan, untuk kemudian dilakukan pemeriksaan hitung jumlah dan jenis bakteri orofaring. Uji statistik menggunakan paired ttest, Wilcoxon, dan Mann Whitney (dengan derjat kemaknaan < 0,05).Hasil : Pada penelitian ini didapatkan penurunan jumlah bakteri orofaring pada kelompok chlorhexidine sebesar 140±76,625 (berbeda bermakna, p=0,000) sedangkan pada kelompok povidone iodine sebesar 100,80±97,209 (berbeda bermakna, /p=0,008). Sedangkan pada uji selisih komparatif kedua kelompok didapatkan hasil berbeda tidak bermakna(p=0,234).Kesimpulan : Penurunan jumlah bakteri orofaring pada tindakan oral hygiene dengan chlorhexidine 0,2% tidak berbeda bermakna dengan povidone iodine 1%.
Perkembangan Sirkuit Anestesi
Authors: Nugroho Taufik Eko , Sasongko Himawan , Soenarjo Soenarjo
Published: December 2022

Bagi seorang ahli anestesi, pemahaman terhadap fungsi dari sistem penghantaran anestesi ini sangatlah penting. Berdasarkan fakta dari data American Society of Anesthesiologists (ASA), Caplan menemukan bahwa meskipun tuntutan dari pasien terhadap kesalahan dari sistem penghantaran anestesi jarang terjadi, akan tetapi ketika itu terjadi maka akan menjadi suatu masalah yang besar, yang sering mengakibatkan kematian atau kerusakan otak yang menetap. Sirkuit anestesi atau dikenal dengan sistem pernafasan merupakan sistem yang berfungsi menghantarkan oksigen dan gas anestesi dari mesin anestesi kepada pasien yang dioperasi. Sirkuit anestesi merupakan suatu pipa/tabung yang merupakan perpanjangan dari saluran pernafasan atas pasien. Sirkuit anestesi diklasifikasikan sebagai rebreathing dan non-rebreathing berdasarkan ada tidaknya udara ekspirasi yang dihirup kembali. Sirkuit ini juga diklasifi kasikan sebagai open, semi open, semi closed dan closed berdasarkan ada tidaknya (1) reservoir bag, (2) udara ekspirasi yang dihirup kembali (rebreathing exhaled gas), (3) komponen untuk menyerap korbondioksia ekspirasi serta (CO2 absorber) (4) katup satu arah.
In vitro study of the antimitotic power and in vivo acute toxicity of aqueous and organic extracts of the aerial part of Haloxylon scoparium Pomel. and evaluation of the correlation between the chemical profile and their biological activities
Authors: Lachkar Nacima , Lamchouri Fatima , Bouabid Khadija , Senhaji Souad , Boulfia Mohamed , Akabli Taoufik , Zalaghi Abdelouahab , Toufik Hamid
Published: December 2022

The present study was conducted on the extracts from the aerial part of Haloxylon scoparium Pomel. The current research has focused on the evaluation of the antimitotic activity with the Lepidium sativum phytotest on aqueous (decocted, infused, macerated) and organic extracts (methanolic extract, methanolic macerated, ethyl acetate extract, chloroform extract and petroleum ether extract) extracts of the aerial portion of Haloxylon scoparium. In order to visualise the correlation between the content of chemical compounds in the aqueous and organic extracts with the results of the Lepidium sativum phytotest, we have used the principal component analysis (PCA). Then, we were interested in studying the acute in vivo toxicity of the methanolic extract and the decocted of Haloxylon scoparium. Antimitotic activity has shown that the methanolic extract exhibited high inhibition of Lepidium sativum germination (IC50=128.16±3.89 µg/mL) than colchicine (IC50=474.66±1.86 µg/mL). The decocted also showed high inhibition compared to the other aqueous extracts (IC50=1359.00±106.69 µg/mL). The correlation study showed that there is a strong correlation between Lepidium sativum phytotest and total polyphenol (r=0.9453) and flavonoid (r=0.9884) composition. In addition, the MLD50 of the methanolic extract and the decocted was estimated at 2000 mg/kg. The present study shows that Haloxylon scoparium could be a potential antimitotic of low toxicity.
New observations on the rarely reported tropical dinoflagellates Tripos lanceolatus and T. schroeteri from the Colombian Caribbean, South Pacific and Indian Oceans
Authors: Castro-Cera Luis , Vega-Díaz Darío , Eriksen Ruth S. , Leblanc Karine , Hallegraeff Gustaaf M.
Published: December 2022

We report the circumtropical dinoflagellate Tripos lanceolatus (Kofoid) F. Gómez from the Colombian Caribbean, provide a new record from the tropical western Pacific off Tonga, and the first record from the Australian sector of the Indian Ocean. We present the first scanning electron micrographs of thecal ornamentation and apical pore structure which show its morphological similarities to T. furca (Ehrenberg) F. Gómez within the subgenus Biceratium. We also report the more widely distributed tropical species T. schroeteri (B. Schröder) F. Gómez from the Colombian Caribbean, and compare it to the first scanning electron micrographs of the morphologically similar T. digitatus (F. Schütt) F. Gómez within the subgenus Archaeceratium.
Empowering quality data – the Gordian knot of bringing real innovation into healthcare system
Authors: Horgan Denis , Hamdi Yosr , Lal Jonathan A. , Nyawira Teresia , Meyer Salomé , Kondji Dominique , Francisco Ngiambudulu M. , De Guzman Roselle , Paul Anupriya , Nallamalla Krishna Reddy , Park Woong-Yang , Triapthi Vijay , Tripathi Ravikant , Johns Amber , Singh Mohan P. , Phipps Maude E. , Dube France , Abu Rasheed Hadi Mohamad , Kozaric Marta , Pinto Joseph A. , Stefani Stephen Doral , Aponte Rueda Maria Eugenia , Alarcon Ricardo Fujita , Barrera-Saldana Hugo A.
Published: December 2022

Objectives

The introduction of Personalised Medicine (PM) into healthcare systems could benefit from a clearer understanding of the distinct national and regional frameworks around the world. Recent engagement by international regulators on maximising the use of real-world evidence (RWE) has highlighted the scope for improving the exploitation of the treasure-trove of health data that is currently largely neglected in many countries. The European Alliance for Personalised Medicine (EAPM) led an international study aimed at identifying the current status of conditions.

Methods

A literature review examined how far such frameworks exist, with a view to identifying conducive factors – and crucial gaps. This extensive review of key factors across 22 countries and 5 regions revealed a wide variety of attitudes, approaches, provisions and conditions, and permitted the construction of a comprehensive overview of the current status of PM. Based on seven key pillars identified from the literature review and expert panels, the data was quantified, and on the basis of further analysis, an index was developed to allow comparison country by country and region by region.

Results

The results show that United States of America is leading according to overall outcome whereas Kenya scored the least in the overall outcome.

Conclusions

Still, common approaches exist that could help accelerate take-up of opportunities even in the less prosperous parts of the world.
Slope characteristics of urban construction land and its correlation with ground slope in China
Authors: Duan Junhao , Peng Qiuzhi , Huang Peiyi
Published: December 2022

Since the 21st century, China’s urban construction land has been growing rapidly, piquing academic interest. However, mountainous counties account for the majority in China, previous studies have concentrated on the horizontal expansion characteristics of construction land, leaving a gap in the vertical expansion. This study used datasets for urban construction land and digital elevation model to analyze the spatiotemporal evolution characteristics of construction land slope in 2670 China’s counties, by exploratory spatial data analysis. Furtherly, we explored the slope relationship between ground and construction land using regression analysis. The findings indicate what follows: (1) The average slope of construction land had a spatial pattern of “high in the south and low in the north,” with significant spatial agglomeration characteristics. And it had increased with the urban expansion, shifting the slope-weighted mean center toward the southeast while enhancing spatial agglomeration. (2) There was a significant and steadily rising linear association between the urban construction land slope and ground slope, due to spatial heterogeneity; the most affected counties were primarily located near the Sichuan basin. According to the results, we provided suggestions for the rational use and sustainable development of land in cities, especially for mountainous regions in a period of rapid urbanization.
Revisiting English written VP-ellipsis and VP-substitution: a dependency-based analysis
Authors: Dai Zheyuan , Liu Haitao , Yan Jianwei
Published: December 2022

The present study quantitatively investigates the structural features of English written VP-ellipsis (VPE) and VP-substitution (VPS) under the theoretical framework of dependency grammar. Results show that: (a) Both VPE and VPS are human language mechanisms that follow the least effort principle; (b) Dependency distance of segmental and discontinuous linguistic units under the influence of VPE and VPS conform to the right-truncated Zipf-Alekseev distribution; (c) Dependency-based indices are effective in distinguishing similar structures of VPE and VPS, especially the Do-Support in ellipsis and Do + X in substitution. The study not only explores the regularity of partial segments of human language under the mechanisms of VPE and VPS, but also offers quantitative evidence for distinguishing confusing structures in VPE and VPS, which may aid in raising the retrieving precision of similar linguistic structures in corpora.
Effects of UV stress on Shewanella azerbaijanica bioremediation response
Authors: Ghasemi Razieh , Talebloo Newsha , Parsa Parisa , Saffarian Parvaneh , Baradaran Samaneh , Zarei Mahsa , Fatemi Faezeh
Published: December 2022

Shewanella azerbaijanica roles as a live electrode, passing electrons from electron donors to electron acceptors, to gain energy from the extracellular electron transfer (EET) pathway. The present study, considered the quantitative expressions of the major EET reductase genes (mtr cluster), together with uranium removal, live-cell counting, and spectrophotometry in UV-C treated bacteria (0, 60, 120 and 180 s). The simultaneous decline in the uranium removal and cell counting, along with major mtr gene expression patterns (mtrABDEF), approved the negative effects of UV-C radiation on uranium bioreduction in S. azerbaijanica. Uranium removal and cell counting decreased to 25.49% and 0.45 × 109 cells/mL in the 180s UV-C treated sample, respectively at 2 mM uranium concentration, while no decline trend found in 0.5 mM for the counted cells and uranium removal tests. No considerable expression of omcA and omcB (mtrC) genes were traced due to spontaneous mutagenesis during the in vitro serial passages, proposing a novel alternative EET pathway in S. azerbaijanica during uranium bioreduction process. The results could pave the way for further researches to modify the bioremediation process through genetic manipulation.
Ankunft im Museum
Authors: Sagurna Stephan
Published: December 2022

Annelise Kretschmer (1903–1987) zählt zu den bedeutenden deutschen Fotografinnen des 20. Jahrhunderts. Bereits während der Frühphase ihres Schaffens in der Weimarer Republik hat sie internationale Anerkennung erfahren. Ihr fotografischer Nachlass wurde über 30 Jahre von ihrer Tochter bewahrt und konnte Ende 2019 durch das LWL-Museum für Kunst und Kultur in Münster erworben werden. Der Beitrag schildert Weg und Workflow zur Übernahme des Konvoluts in die Sammlung des Museums mit dem erklärten Ziel den Bestand zu sichern, zu bearbeiten, zu präsentieren und für zukünftige Nutzungen zugänglich zu machen. In der chronologischen Abfolge des Projektberichts werden entscheidende Arbeitsschritte, Strategien und Herausforderungen beschrieben. Große und kleine Fortschritte, Projektmeilensteine und kritische Situationen finden ebenso Berücksichtigung wie Ereignisse, die direkten und indirekten Bezug zu Leben und Werk von Annelise Kretschmer aufweisen. Als Arbeitsprotokoll bietet der Bericht Einblicke in ein fotohistorisches Erschließungs- und Präsentationsprojekt und soll Inspiration und Anleitung im Umgang mit weiteren fotohistorischen Sammlungen sein.
Why Tickle the Dragon’s Tail?
Authors: Yu Ching-hsin
Published: December 2022

The security situatsssion across the Taiwan Strait has recently deteriorated rapidly. Scholars and policymakers have attributed this development to the concurrence of an increasingly assertive Communist Party in China, a unilateralist Trump administration in the US, and a new DPP government in Taiwan since 2016. For the Taiwanese, the security concern is on their doorstep, but their attitudes are under-studied. I find that judgments of China’s animosity to Taiwan, China’s importance for Taiwan’s economy, (dis)agreement with the “one country, two systems” formula, concern regarding developments in Hong Kong, (dis)agreement with alliance with Japan and the US, (dis)belief in the US’s security commitment to Taiwan, and perception of the comparative strength of China versus the US are closely associated with respondents’ choice to ally with China or the US. These findings also shed light on Taiwanese (over)optimism regarding the US’s role in the wake of Chinese invasion of Taiwan.
Democratic Performance, Secular–Traditional Value Orientation, and Satisfaction with Democracy in India and Pakistan
Authors: Hassan Bilal
Published: December 2022

This paper examines the associations between democratic performance, secular–traditional value orientation, and satisfaction with democracy in India and Pakistan through the lens of democratic performance and modernization theory. In an analysis of data from the 2012 World Values Survey, respect for human rights (one of two measures of democratic performance) has a stronger effect on satisfaction with democracy in India than in Pakistan. Freedom of choice influenced satisfaction with democracy only in India. Rather than having a direct effect, secular–traditional value orientation moderates the relationship between freedom of choice and satisfaction with democracy.
Global Reproductive Governance after Dobbs
Authors: Morgan Lynn M.
Published: December 2022

The 2022 US Supreme Court decision Dobbs v. Jackson Women’s Health overturned the constitutional right to abortion, raising questions about the international implications of the ruling. The Dobbs decision reveals a growing rift in global reproductive governance between countries that rely on international human rights standards and those that do not. The global momentum is currently with the human rights contingent, but the Dobbs ruling reflects the logic of a global antiabortion coalition that would like each country to decide its own life and family laws, without interference from multilateral agencies, based on its own constitution, history, and traditions.
Global Chopin: The 1949 Centenary and Polish Internationalism during the Early Cold War
Authors: Pierce J. Mackenzie
Published: December 2022

The 1949 Chopin Year was a large-scale cultural mobilization whose purpose was to bring Chopin’s music to hundreds of thousands of Poles and to promote it around the world, all funded and overseen by Poland’s newly established Communist state. Among the most striking aspects of the Chopin Year was its extensive international programming: not only did Polish diplomatic missions convince around thirty countries to organize Chopin celebrations that paralleled those in Poland, but they targeted countries outside the Soviet-dominated Eastern Bloc, despite the strictures of Stalinist-era anti-Westernism then growing across Eastern Europe. This article draws on unstudied archival sources from Polish ministries, musical institutions, and diplomatic missions to explore the historical and political forces at play in Poland’s Chopin-centered internationalism during the early Cold War. I demonstrate that cultural officials, composers, diplomats, and performers—all with varying stakes in state socialism—competed over the meaning of Chopin and his accomplishments when planning the Chopin Year. These various factions often agreed, however, on a decades-old view of the composer as both a national and an international figure, whose legacy was uniquely capable of promoting Polish causes on the global stage. By showing how the Chopin Year drew on and perpetuated a longue durée of Polish transnational contacts and discourse about the global Chopin, the article places Cold War internationalism within a longer lineage of border-crossing that had been a central aspect of European musical culture since at least Chopin’s lifetime.
Liraglutide 3.0 (Saxenda) in bariatric patients: a retrospective real-world clinical evaluation of effectiveness
Authors: Simenacz Amelia , Wilmington Rebekah , Green Carol , Ardavani Arash , Idris Iskandar
Published: December 2022

Background: Glucagon-like peptide-1 analogues such as liraglutide 3.0 mg (Saxenda) have yielded signiﬁcant weight loss in clinical trials when combined with lifestyle interventions. Despite the recent approval of liraglutide 3.0 mg, its success among patients attending specialist bariatric units remains uncertain.
Objective: This study investigated the effectiveness of liraglutide 3.0 mg on weight, body mass index (BMI), treatment tolerability and its effects on glycated haemoglobin (HbA1c).
Methods: Clinical data were retrospectively obtained from medical records within Tier 3-4 bariatric weight management clinics. Wilcoxon signed rank tests were employed to establish the statistical signiﬁcance (p<0.05) of changes in weight and HbA1c.
Results: 33 patients were identiﬁed (72.7% female with mean baseline age, weight and BMI of 44.8 years, 156.6 kg and 55.0 kg/m2, respectively). Eighteen patients had completed 26 weeks of treatment. Of the 18 patients, the discontinuation rate due to side effects was 15.2%, indicating substantial treatment tolerance. After 26 weeks of treatment, BMI (±standard deviation) was signiﬁcantly reduced by 7.9±6.3% (p<0.05) and 72.2% of patients achieved at least 5% weight loss. Additionally, a signiﬁcant decrease in median HbA1c (4.5±4.5 mmol/mol) was observed (p<0.05), concurrent with increased remission from prediabetes.
Conclusion: This retrospective study revealed that liraglutide 3.0 mg, together with lifestyle management, reduced weight and improved glycaemic control. These results support liraglutide’s application in certain high-risk populations, including patients waiting for bariatric surgical intervention.
brief history of the UK Prospective Diabetes Study
Authors: Holman Rury
Published: December 2022

The UK Prospective Diabetes Study (UKPDS) epidemiological ﬁndings conﬁrmed that T2DM is not a “mild” disease, with roughly 50% of patients having clinically evident complica- tions at diagnosis, emphasising the need for its early detection and treatment. Hyperglycaemia was identiﬁed as an independent coronary heart disease risk factor, with progressive hyperglycaemia shown to be a major pathophysiological feature of T2DM, driven by declining beta-cell function. People with T2DM and hypertension were found to be at double jeopardy for any diabetes endpoint, and worsening kidney function was shown to increase the risk of death substantially.
The UKPDS 20-year trial results were the ﬁrst to demon- strate that diabetic complications are not inevitable but can be prevented by more intensive blood glucose control and by metformin therapy, changing T2DM management guide- lines worldwide. The UKPDS also showed that tighter blood pressure control prevents diabetic complications; the beneﬁts of the glucose and blood pressure interventions are additive. The UKPDS 10-year post-trial monitoring study was the ﬁrst to identify the T2DM glycaemic and metformin legacy effects, with early more intensive therapy having continuing beneﬁts long after the trial terminated. The trial demon- strated the need to achieve good glycaemic control as early as possible to minimise the risk of future complications.
origins of type 2 diabetes medications
Authors: Bailey Clifford J
Published: December 2022

The origins of diabetes medications provide an intriguing catalogue of clinical serendipity and scientiﬁc design. Use of insulin (beyond 1922) gave recognition to insulin resistance and the categorisation of type 2 diabetes (T2DM). The ﬁrst sulphonylurea (carbutamide, 1956) emerged from its use as an antibacterial sulphonamide prone to cause hypoglycaemia, and biguanides were ﬁrst used to treat diabetes in 1957 despite their glucose-lowering properties having been known since the 1920s. Alpha-glucosidase inhibitors arose from a screening programme for amylase inhibitors by Bayer in the 1970s and acarbose was introduced in 1990. The ﬁrst thiazolidinedione (ciglitazone; not developed) was identiﬁed in a screening programme for triglyceride-lowering compounds by Takeda in the late 1970s and gave rise to pioglitazone (approved 1999), although ﬁrst to market was troglitazone (from Warner Lambert 1997, withdrawn 2000). Exendin, an analogue of the incretin hormone glucagon-like peptide-1 (GLP-1), was identiﬁed in 1992 in the saliva of a lizard (Heloderma suspectum), and took until 2005 to be marketed as exenatide. To promote the efﬁcacy of endogenous GLP-1, its rapid inactivation by the enzyme dipeptidylpeptidase-4 (DPP4) was blocked by clever molecular design of the ﬁrst DPP4 inhibitors (vildagliptin and sitagliptin, approved in 2006). SGLT2 inhibitors are based on phlorizin, identiﬁed in apple tree bark (1835) and modiﬁed (2000) to avoid intestinal degradation: further modiﬁcations to increase selectivity against SGLT2 gave dapagliﬂozin and canagliﬂozin - approved 2012 and 2013, respectively, in Europe.
Modification of TSH-related genetic effects by indicators of socioeconomic position
Authors: Drogge Sophie-Charlotte , Frank Mirjam , Girschik Carolin , Jöckel Karl-Heinz , Führer-Sakel Dagmar , Schmidt Börge
Published: December 2022

Objective

Thyroid-stimulating hormone (TSH) is influenced by genetic and environmental factors such as socioeconomic position (SEP). However, interactions between TSH-related genetic factors and indicators of SEP have not been investigated to date. The aim of the study was to determine whether education and income as SEP indicators may interact with TSH-related genetic effect allele sum scores (GESTSH_2013 and GESTSH_2020) based on two different GWAS meta-analyses that affect TSH values in a population-based study.

Methods

In 4085 participants of the Heinz Nixdorf Recall Study associations between SEP indicators, GESTSH and TSH were quantified using sex- and age-adjusted linear regression models. Interactions between SEP indicators and GESTSH were assessed by GESTSH × SEP interaction terms, single reference joint effects and calculating genetic effects stratified by SEP group.

Results

Participants within the highest education group showed the strongest genetic effect with on average 1.109-fold (95% CI: 1.067–1.155) higher TSH values per GESTSH_2013 SD, while in the lowest education group, the genetic effect was less strong (1.061-fold (95% CI: 1.022–1.103)). In linear regression models including interaction terms, some weak indication for a positive GESTSH_2013 by education interaction was observed showing an interaction effect size estimate of 1.005 (95% CI: 1.000–1.010) per year of education and GESTSH_2013 SD. No indication for interaction was observed for using income as SEP indicator. Using the GESTSH_2020, similar results were observed.

Conclusion

Our results gave some indication that education may affect the expression of TSH-related genetic effects. Stronger genetic effects in high-education groups may be explained by environmental factors that have an impact on gene expression and are more prevalent in high SEP groups.
Metformin Improves Ovarian Function and Increases Egg Production in Broiler Breeder Hens
Authors: Weaver Evelyn A , Ramachandran Ramesh
Published: December 2022

Broiler breeder hens, the parent stock of commercial broiler chickens, have poor reproductive efficiency associated with aberrant and excessive recruitment of ovarian follicles which results in sub-optimal egg production, fertility, and hatchability. The reproductive dysfunction observed in these hens resembles polycystic ovary syndrome in women, a condition wherein metformin is prescribed as a treatment. The main objectives of this study were to determine the effect of metformin on body weight, abdominal fat pad weight, ovarian function, and plasma steroid hormone concentrations. Broiler breeder hens were treated with 0, 25, 50, or 75 mg/kg body weight of metformin mixed in the diet for 40 weeks (n= 45 hens/treatment; 25-65 weeks of age). At 65 weeks of age, hens that received the highest dose of metformin had significantly lower body and abdominal fat pad weights (p < 0.05) than the control. Metformin treatment, at all levels, normalized the preovulatory and prehierarchical ovarian follicular hierarchy. Metformin (50 or 75 mg/kg body weight) significantly increased the total number of eggs laid per hen during the entire production period and these hens had significantly greater fertility and hatchability at 65 weeks of age compared to the control (p < 0.05). Metformin treatment at all levels altered the plasma profile of reproductive hormones, with significantly lower plasma testosterone concentrations and a decreased testosterone to androstenedione ratio in hens that received metformin (p < 0.05). Future studies should focus on the mechanisms underlying the beneficial effects of metformin in improving the reproductive efficiency of broiler breeder hens.
Treating Complications of Extracorporeal Life Support in a Patient with COVID-19 (Case Report)
Authors: Rybalko A. S. , Galkina S. N. , Saryglar A. S. , Kolerov V. A. , Voronin A. V. , Perekhodov S. N. , Karpun N. A.
Published: December 2022

We present a case of mechanical hemolysis as a complication of extracorporeal membrane oxygenation (ECMO) occurring in a COVID-19 patient as a result of pump head thrombosis. After emergency extracorporeal circuit replacement, hemoadsorption was initiated to address the negative hemolysis effects and plasma free hemoglobin rise in the setting of rapid clinical deterioration and impaired renal function. During therapy hemolysis severity reduced, the lactate dehydrogenase (LDH) levels decreased, while the P/F ratio increased two-fold. The patient was discharged from hospital on day 54 without the need for either oxygen therapy or dialysis. In the discussion section we addressed frequent issues of choosing therapy for ECMO complications.

Conclusion.The timely, properly chosen, and clinically relevant use of hemoadsorption combined with advanced high-technology therapeutic procedures can have a positive impact on the patient's outcome.
Osman Nuri Demir. Mâtürîdî’de İnsan Tasavvuru, İstanbul: Türkiye Diyanet Vakfı Yayınları, 2020, 302 sayfa.
Authors: ÇINAR Muhammed
Published: December 2022

Modern Batı düşüncesinin kendi geleneğini eleştirel bir dille yorumladıktan sonra yeni bir bilgi ve varlık felsefesi inşa etmesi İslam coğrafyasında da yenilik arayışlarının başlamasına zemin teşkil etmiştir. Bu arayışlar İmam Mâtürîdî (ö. 333/944) ve Mâtürîdîlik eksenli yeni bir kelam dili ve anlayışı oluşturma teşebbüsünü gündeme getirmiş, bu durum da son dönemde hatırı sayılır bir literatürün ortaya çıkmasını sağlamıştır. Osman Nuri Demir’in 2019 yılında tamamladığı Mâtürîdî’de İnsan Tasavvuru başlıklı doktora tezinin gözden geçirilmiş ve kısmi tasarruflarda bulunularak 2020 yılında aynı adla yayımlanmış çalışması bu literatürün son örneklerinden biridir. Eser, Mâtürîdîlik üzerinden yeni bir kelami anlayış oluşturmayı denemesi hasebiyle incelenmeyi hak etmektedir. Burada, Demir’in eserinde belirlediği kapsam ve çerçeve, öne sürdüğü iddiaların tutarlılığı ve ulaşılan sonuçların yeterliliği değerlendirilecektir.
Activated carbon and cellulose-reinforced biodegradable chitosan foams
Authors: Ergun Mehmet Emin
Published: December 2022

Chitosan foams with promising mechanical properties, heat-insulating ability, and flame retardancy were produced through oven drying. The chitosan foams were reinforced with cellulose, boric acid, and different ratios of activated carbon. The foams showed desirable low density (80.2 to 109.8 kg/m3) and compression properties. The compression resistance and compression modulus of foams ranged between 53.6 and 98.5 KPa and 214 to 394 KPa, respectively. Thermal conductivity tests revealed that the foams endowed low thermal conductivity values (0.035 to 0.051 W/mK). The limiting oxygen index (LOI) of the foams was as high as 32.9% for activated carbon (20 g/L). The activated carbon reinforcement produced higher thermal properties and decreased the mass loss 48.1% at 600 °C. The produced foams exhibited good biodegradability (39% degradation in 15 days). The overall test results showed that the chitosan foams can be utilized as a promising environmentally friendly material in thermal insulation fields.
Perception Against
Authors: Abram Sandi , Bajič Blaž
Published: December 2022

The paper seeks to contribute to critical reflection on recent trends in cultural anthropology, the humanities more generally, and ongoing transformations of urban space. The first part of the paper explores the genealogy of two crucial anthropological approaches to “the life of the senses,” anthropology of the senses, and sensory anthropology, outlines their relationship to so-called walking methodologies, and relates them to the recent upsurge of research in atmospheres. The second part presents selected topics from the described fields in Ljubljana. More specifically, the paper deals with how, during sensobiographic walking through the historical city center, Ljubljančani and Ljubljančanke experienced what “atmospheric transformations” ushered in by Ljubljana’s annual December celebrations/festivities. The authors conclude that concepts and epistemological frameworks produced or implicated in the anthropology of the senses/sensory anthropology, as well as in walking methodologies and atmospheric studies, engender an examination of sensory dimensions of politics and economy in late capitalism but are appropriated in a reified form for purposes of capital accumulation.
Žena, majka, kraljica
Authors: Kupsjak Jelena
Published: December 2022

Kroz analizu reklamnih kampanja za dodatak prehrani koji obećava povratak sreće ovaj članak problematizira regulatorne učinke potrage za srećom u kontekstu tranzicije i popularizacije novih oblika ženskosti u Hrvatskoj. Članak ukazuje na rodne dimenzije “tranzicije” kroz analizu njezinih materijalizacija u kontekstu popularne kulture. S fokusom na orodnjeno mentalno zdravlje, analiza se oslanja prije svega na rad Sare Ahmed o afektivnosti društvenih normi i ideala kao i na rad Lilijane Burcar koji se bavi odnosom kapitalizma i patrijarhata u postjugoslavenskom prostoru.
Learning the single-dominant modal system on resonant sloshing in a rectangular tank
Authors: Milyaev A.O. , Timokha A.N.
Published: December 2022

A machine learning technique is proposed to derive the damping rate functions in the co-called single-dominant modal system describing the resonant liquid sloshing in a rectangular tank performing harmonic longitudinal motions. Its implementation is demonstrated for the steady-state (periodic) resonance waves when the modal system admits an analytical asymptotic solution depending on the introduced damping rate functions. Recent experiments by Bäuerlein & Avila (2021) are employed to show that the viscous damping of the higher natural sloshing modes matters, and the damping functions depend on the wave amplitude.
Синтез N-метил 3-алкіл-ізотіазолідин-1,1-діоксо-3-метилкарбоксилатів за внутрішньомолекулярною реакцією Міхаеля
Authors: Іжик В.В. , Добриднєв О.В. , Попова М.В. , Воловенко Ю.М.
Published: December 2022

Розроблено ефективний та простий у виконанні метод синтезу N-метил 3-алкіл-ізотіазолідин-1,1- діоксо-3-метилкарбоксилатів. Як вихідні реагенти використовуються легкодоступні гідрохлориди естерів 2-монозаміщених α-амінокислот та β-хлоретилсульфонілхлорид. Отримані на першій стадії метил 2-алкіл-2-(вінілсульфамідо)етаноати алкілуються за атомом нітрогену і перетворюються на метил 2-алкіл-2-(N-метилвінілсульфамідо)етаноати, які в умовах NaH-опосередкованої внутрішньомолекулярної реакції Міхаеля циклізуються в цільові N-метил 3-алкіл-ізотіазолідин-1,1-діоксо-3-метилкарбоксилати. Даний клас сполук розглядається як сульфамідний біоізостер природної піроглутамінової кислоти (pGlu) і може використовуватися в синтезі сполук з потенційною біологічною активністю.
Teoría y deificación del amor en Félix Grande: de «Las Rubáiyátas» a la narrativa breve
Authors: Gómez-Vaquero Alberto , Parratt-Fernández Sonia , Mera-Fernández Montse
Published: December 2022

El amor fue una de las grandes preocupaciones de Félix Grande durante más de tres décadas de trayectoria, desde el relato «Música para mi hijo» (1963) hasta Sobre el amor y la separación (1996). El objetivo de este artículo es analizar la temática amorosa tanto en el poemario Las Rubáiyátas de Horacio Martín como en la narrativa breve del autor publicada en libros, revistas y periódicos. Para ello se examinan la articulación de las relaciones entre los implicados en la trama amorosa y las ideas sobre el amor que expresan personajes y narradores. Se concluye que el amor forma parte del universo poético de Grande y por eso aparece en diferentes etapas y estilos del autor: de sus relatos emerge una teoría que se va haciendo más consciente y explícita, hasta devenir en un sistema cuasi religioso que pretende explicar el poder que el amor tiene sobre los individuos.
Tadeusz Czeżowski – obszary filozofowania
Authors:   Akademia Ekonomiczno-Humanistyczna w Warszawie, Polska, Słomski Wojciech
Published: December 2022

This article presents the views of Tadeusz Czeżowski, who was one of the most prominent representatives of the Lviv-Warsaw school. He formulated a number of rules defining the rules of conducting science. His most important conclusion is that also metaphysical theories have a specific logical structure, i.e. they are interpretations of logic, therefore there is nothing to prevent metaphysics from also being considered as a branch of science. According to Czeżowski, there are two types of ethical theories: empirical ethics, and deductive ethics. Czeżowski, however, did not attempt to create his own ethical system.
Pomiędzy tradycją a filozofią analityczną. Karola Frenkla (1891–1920) droga do etyki naukowej
Authors:   Uniwersytet Zielonogórski, Polska, Konstańczak Stefan
Published: December 2022

Karol Frenkel took as the object of his research the inner need to come to terms with the tradition in which he had been brought up. He developed an original conception of independent ethics. In his doctoral thesis, he analysed two competing ethical systems formulated by David Hume and Arthur Schopenhauer, which sought ethical determinants in the affective sphere. These proposals proved unsatisfactory to him, which is why he proposed his own solution, derived from his understanding of the concept of morality. From today’s perspective, it was the first attempt to formulate a concept of analytic ethics, which chronologically speaking preceded the analogous solutions proposed by George Moore in Principia Ethica.
Etyczny wymiar idei wychowawczych i inicjatyw społecznych w Galicji w dobie autonomii
Authors:   Uniwersytet Rzeszowski, Polska, Grzybek Grzegorz
Published: December 2022

The article analyses the educational ideas and social initiatives of the period of autonomy in Galicia, revealing several important elements. Two aspects should be pointed out by taking into account the rationale of the social principles of the Catholic Church, for which the impetus was provided by Leo XIII’s encyclical „Rerum novarum”, The focus on ‘catholicity’ shaping an identity for a reborn nation does not have a universalist dimension for a pluralistic society. The socio- -political situation only partially justifies this approach. The social work undertaken by the clergy and those associated with the Catholic Church has made it possible to rebuild trust in the Church.
ВИКОРИСТАННЯ ГІДРОДИНАМІЧНОЇ КАВІТАЦІЇ ДЛЯ ПІДВИЩЕННЯ ЕФЕКТИВНОСТІ ПРОЦЕСУ КРИСТАЛІЗАЦІЇ ЛАКТОЗИ В МОЛОЧНІЙ СИРОВАТЦІ
Authors: Іваницький Георгій Костянтинович , Целень Богдан Ярославович , Радченко Наталія Леонідівна
Published: December 2022

Проведено аналіз проблем у галузі переробки молочної сироватки. В ході якого встановлено перспективність даного напрямку, сформульовано мету і завдання досліджень. В рамках роботи розглянуто існуюче в Україні і світі обладнання, зокрема, його переваги і недоліки. На основі чого авторами було запропоновано використання роторно-пульсаційного апарата спеціальної конструкції типу ротор-статор-ротор. Проведені дослідження на запропонованому експериментальному обладнанні дозволили вивчити вплив гідродинамічної обробки на процес кристалізації молочної сироватки та досягти покращення перебігу процесу кристалізації лактози в сироватці. Зокрема, в роботі доведено, що обробка сироватки з використанням в комплексі вакуумної камери та роторно-пульсаційного апарата спеціальної конструкції типу ротор-статор-ротор перед стадією кристалізації лактози дозволяє отримувати кристали меншого розміру з вузьким дисперсним розподілом в діапазоні від 5,0 до 6,5мкм, у порівнянні, з традиційними технологіями, де розміри кристалів досягають 20мкм. Запропонована конструкція дозволяє підвищити продуктивність, забезпечити рівномірну обробку потоку рідини, а також збільшити швидкість обертання ротора для більш інтенсивного гідродинамічного впливу на рідину. У підсумку проведеної роботи авторами було рекомендовано використання даного обладнання в технологіях сушіння сироватки молока, з метою отримання продукту високої якості. Рекомендований режим рециркуляції протягом 2 хв. перед стадією кристалізації лактози.
RESEARCH OF THE KINETICS OF THE DRYING PROCESS OF COMBINED PLANT MATERIALS
Authors: Petrova Zhanna , Slobodianiuk Kateryna , Samoilenko Kateryna , Vishnevsky V. M. , Grakov Oleksii
Published: December 2022

The general trend of energy consumption, which leads to an increase in the amount of energy consumed in the world, has shown that its cost is constantly increasing, and the shortage of energy carriers is increasing. So, the problem of creating and large-scale implementation of modern energy-efficient heat-technologies, which ensure the reduction of energy consumption and the maximum preservation of the high quality of the dehydrated product, is relevant today.
In order to solve the above-mentioned problem, this work has developed an innovative pre-treatment of combined plant materials. A study of pH results for different ratios of red beetroot with rhubarb/tomato is presented. We managed to obtain the most optimal content of components in the red beetroot:rhubarb mixture as 2:1, with a pH value of 3.75, and betanin in the studied material after drying remains at the level of 96.5% for red beetroot:tomato - 3:1, in which pH is 3.9, and betanin is 94.7%. Also, with the preservation of earnings and increasing the functionality of the phytoestrogen properties of plant raw materials, the conditions for the stabilization of plant ingredients have been developed. Mixtures of plant materials with different ratios of initial components of plant origin were created and optimal drying modes were developed.
The kinetics of the drying process of combined plant materials with their preliminary preparation was experimentally investigated.
On the basis of the obtained data on the change in the nature of the Rebinder number depending on the humidity, the combined plant material and the temperature of the heat carrier, staged drying regimes were developed.
The theoretical processing of the obtained experimental data on the red beetroot:tomato mixture was performed according to the method of V.A. Danilov. The generalized drying kinetics curves of the red beetroot:tomato mixture coincide with the fast drying regimes.
The duration of the drying process of the soybean:spinach mixture on the experimental convective stand was calculated according to the method of V.V. Krasnikov. The generalized curve of the drying kinetics of the soybean:spinach mixture made it possible to apply the relative drying coefficients. And it became possible to calculate the total drying time of the soybean:spinach mixture. The deviation of the calculated value from the experimental duration of drying does not exceed 5%.
ДОСЛІДЖЕННЯ МЕХАНІЧНИХ ВЛАСТИВОСТЕЙ БІОКОМПОЗИТІВ НА ОСНОВІ КУКУРУДЗЯНОГО КРОХМАЛЮ
Authors: Шунькін Ігнат Сергійович , Сухий Костянтин Михайлович , Третьяков Артем Олегович , Черваков Денис Олегович , Бєляновська Олена Анатоліївна
Published: December 2022

Стаття присвячена створенню композитів на основі кукурудзяного крохмалю з синтетичним полімером. В роботі вирішуються задачі створення нових матеріалів, що здатні до біорозпаду та, які можна виготовляти з доступної рослинної сировини. В якості синтетичного полімеру застосовано сополімер етилену з вінілацетатом. В ході проведення роботи було досліджена можливість переробки композицій стандартними для полімерів методами, а саме екструзією та литтям під тиском. Було досліджено зміну механічних властивостей біокомпозиту від концентрації синтетичного полімеру. При цьому концентрація змінювалась від 0 до 40 масових відсотків синтетичного полімеру. Отримані результати дають можливість визначити мінімальну концентрацію синтетичного полімеру при якій біокомпозит має мінімально допустимі механічні властивості для його подальшого використання. Це значення складає 20 % синтетичного полімеру і 80% кукурудзяного крохмалю. Проведено порівняння механічних властивостей отриманих під час проведення дослідницької роботи матеріалів з тонажними синтетичними полімерами, такими як полістирол та поліетилен високого та низького тиску. Завдяки такому порівнянню показана можливість застосування отриманих композитів при виробництві упакування та одноразового посуду. Результати наукових досліджень дають можливість прогнозувати властивості біокомпозиту в залежності від співвідношення крохмаль-синтетичний полімер. Таким чином є можливість обирати склад композиції в залежності від вимог до конкретного виробу. Показана здатність композиту на основі крохмалю поглинати вологу. Висока здатність поглинати вологу пластифікованим крохмалем сильно обмежує можливість його використання в чистому вигляді без синтетичного полімеру. Досліджена кінетика процесу для ряда композитів. Досліджено залежність механічних властивостей біокомпозиту від їого вологості. Експериментально встановлено, що з підвищенням вологи в композиті підвищуються його механічні властивості. Також проведені випробування, які свідчать, що отримані композити, навіть ті, які містять максимальну концентрацію синтетичного полімеру проявляють властивості саме біокомпозитів, тобто здатні до біорозпаду у відносно короткий проміжок часу. Для цього був використаний метод Штурма. Досліджено зміну фізико-механічних властивостей в процесі біодеградації отриманих композицій. Це, безумовно є непрямим доказом того, що композити здатні до біорозкладу. Також, такого роду дослідження показують працездатність виробів з біокомпозитів в екстремальних умовах. Таким чином у роботі показані перспективи використання композитів з високим вмістом рослинної сировини – кукурудзяного крохмалю. Такі композиції здатні вирішувати як екологічні задачі, так і економічні, бо по суті вони є альтернативними синтетичним полімерам.
ІННОВАЦІЙНІ ЕНЕРГОТЕХНОЛОГІЇ ПЕРЕРОБКИ ХАРЧОВОЇ СИРОВИНИ
Authors: Щербич Максим Володимирович , Поян Олександр , Сиротюк Ілля Вадимович
Published: December 2022

Проведено критичний аналіз світового досвіду використання електромагнітного випромінювання з метою інтенсифікації тепломасообмінних процесів в ході переробки харчової сировини. Встановлено, що проблеми екстрагування та зневоднення є досить актуальними, вирішення яких призведе до максимально можливого використання енергетичного та сировинного потенціалу. Незважаючи на велике різноманіття проведених досліджень як вітчизняними, так і закордонними науковцями, отримані результати не розкривають реальні можливості мікрохвильових технологій. Відсутність вакууму, високі температури, довготривале термічне навантаження на сировину призводить до значного погіршення якостей кінцевого продукту не дивлячись на інноваційність організації процесу обробки. Для вирішення поставлених задач була запропонована гіпотеза, що використання електромагнітних технологій в процесах зневоднення дозволить організувати видалення вологи із капілярів харчової сировини не лише у вигляді парової фази, а й у вигляді рідини. В такому випадку з’являється можливість суттєво скоротити енерговитрати на процес та отримати абсолютно нові продукти. Результати досліджень показали, що вихід рідкої фази в 4 рази перевищує вихід парової. Даний ефект отримав назву «пародимамічний». Була запропонована технологія комплексної переробки вторинної сировини харчоконцентратних та олієжирових виробництв. В ході проведення експериментальних досліджень була доведена можливість додаткового вилучення цільових компонентів з олієвмісних відходів. Такий принцип утилізації вторинної сировини вирішує цілий ряд проблем харчової промисловості за рахунок різкого зниження втрат продукту, відновлення реагентів та зменшення екологічного навантаження на навколишнє середовище. Лабораторний аналіз отриманих зразків готового продукту свідчить про їх високу якість та безпечність до споживання.
The Early Bronze Age Bowls from Dagestan Coastal Area (Typology, Dйcor and Chronology Issues)
Authors:   Dagestan Federal Research Center of the Russian Academy of Sciences, Budaichiev Arsen
Published: December 2022

The article is devoted to the ceramic bowls study being one of the most exemplary earthenware categories presented in rather large numbers on the Early Bronze Age sites of Dagestan coastal area. The main goal of the study is to develop a typology of the bowls from the settlements (Gheme-tyube I, II, Kabaz-kutan I, II, Torpakh-kala, Ullu-Achi) and the burial grounds (Velikent I, catacomb 8, Velikent II, catacomb 1, Velikent III, catacomb 1, Karabudakhkent II, Kayakent VI) of the region as well as to examine the decor and chronology. According to the shape of the corpus, two main types of bowls are distinguished: type I – bowls in the form of an inverted truncated cone with straight or slightly oval sides at the top; type II – bowls with rounded sides and a slightly everted rim. Type I bowls in the shape of a rim are divided into four subtypes (A, B, C, D). Type II bowls do not have clear varieties. For each type and subtype of the bowls, analogies and parallels are given not only from the regions adjacent to Dagestan, but also from other areas (Eastern and Central Anatolia, Northwestern Iran, etc.), where the Kuro-Arak culture are also widespread. The article identifies common and rare types and subtypes of bowls based on typological analysis and statistical calculations. The paper also deals with the decoration of the bowls which is an episodic phenomenon for them (mortise ornament along the inner edge of the bowl, indented decor). An attempt was made to study the chronology of the bowls, the allocation of early and later types and subtypes on the basis of the monuments’ dating, stratigraphic observations and a series of radiocarbon dating.