bluuebunny/crossref_metadata_2025 huggingface dataset:
Using SITAR (SuperImposition by Translation and Rotation) to estimate age at peak height velocity in Avon Longitudinal Study of Parents and Children
Authors: Frysz Monika , Howe Laura D. , Tobias Jonathan H. , Paternoster Lavinia
Published: July 2018

Puberty is a time of substantial biological and psychological changes. One of the hallmarks of puberty is a rapid growth spurt, however its timing varies between individuals. The impact of pubertal timing on later health outcomes has been of interest in life course epidemiology, however its measurement can be challenging. Age at peak height velocity (aPHV) offers an objective measure of pubertal timing without having to rely on physical examination or self-report. We describe the derivation of aPHV estimates in Avon Longitudinal Study of Parents and Children (ALSPAC) offspring, using Superimposition by Translation And Rotation (SITAR) mixed effects growth curve analysis. ALSPAC is a rich source of phenotypic and genotypic data and given the importance of pubertal timing for later health outcomes, these data offer an opportunity to explore the determinants and consequences of aPHV.
Improving Quality of Preparation of Projects of Regional Development for Example of Kamchatsky Region
Authors: Баталов Дмитрий , Batalov Dmitry
Published: July 2018

The article is devoted to the problem of poor quality preparation of projects for the development of territories in Russia, in particular the Kamchatka region. We consider the current approach to the preparation of projects - Early planning of the project. The article presents the results of the conceptual analysis of the state front-end systems in Norway, the Netherlands, and options for preparing projects / programs that are applied by Russian public authorities. The author formulates problems and conceptual inconsistencies in the preparation of Russian projects / programs. The article compares the approaches to the preparation of business projects by foreign companies with an approach to project preparation by Russian business in cooperation with the public authorities. The article presents the study results, which confirm the low awareness of participants in the project activity on frontend project planning and the initiating document. The results of the survey confirm the hypothesis that there is no phase of project planning in the activities of public authorities and business. The author emphasizes the importance of the application of the initiating document "Business Case", and formulates recommendations for improving the quality of the preparation of territorial projects.
Management of a Shared-Spectrum Network in Wireless Communications
Authors: Wu Shining , Zhang Jiheng , Zhang Rachel Q.
Published: July 2018

We consider a band of the electromagnetic spectrum with a finite number of identical channels shared by both licensed and unlicensed users. Such a network differs from most many-server, two-class queues in service systems, including call centers, because of the restrictions imposed on the unlicensed users to limit interference to the licensed users. We first approximate the key performance indicators—namely the throughput rate of the system and the delay probability of the licensed users under the asymptotic regime, which requires the analysis of both scaled and unscaled processes simultaneously using the averaging principle. Our analysis reveals a number of distinctive properties of the system. For example, sharing does not affect the level of service provided to the licensed users in an asymptotic sense even when the system is critically loaded. We then study the optimal sharing decisions of the system to maximize the system throughput rate while maintaining the delay probability of the licensed users below a certain level when the system is overloaded. Finally, we extend our study to systems with time-varying arrival rates and propose a diffusion approximation to complement our fluid one.

The e-companion is available at https://doi.org/10.1287/opre.2017.1707 .
DIAGNÓSTICO E ANÁLISE-CRÍTICA DA DÍVIDA ATIVA DO MUNICÍPIO DE SALVADOR, E PROPOSTAS PARA O SEU SANEAMENTO
Authors: Portella André Alves , Borges Mário Andrade
Published: July 2018

O presente trabalho objetiva a análise crítica do instituto da Dívida Ativa, a partir do diagnóstico da situação em que a mesma se encontra no Município de Salvador. Por meio do estudo de fontes teóricas especializadas e da verificação de dados empíricos disponibilizados pela Secretaria da Fazenda e pela Procuradoria do Município, será considerada a relevância jurídica e financeira do instituto e realizada a análise da sua situação atual, da sua evolução histórica, do baixo desempenho da recuperação dos créditos inscritos e das razões da formação do seu enorme estoque. Finalmente, serão ponderadas algumas alternativas de saneamento e recuperação, o que inclui tanto a revisão de toda a estrutura e dinâmica da Administração Fazendária, até a adoção dos chamados meios alternativos de soluções de conflitos no âmbito fiscal.
DIREITO URBANÍSTICO E REGULARIZAÇÃO FUNDIÁRIA
Authors: Santin Janaína Rigo , Comiran Rafaela
Published: July 2018

A pesquisa aborda a temática da regularização fundiária no Brasil, tendo como base o Estatuto da Cidade (Lei 10.257/2001), o Estatuto das Metrópoles (Lei 13.089/2015) e a Lei do Minha Casa Minha Vida (Lei 11.977/09). No estudo, pelo método dedutivo, percebe-se como a ocupação desenfreada das cidades, somada à falta de planejamento do governo para a questão da moradia, causam graves problemas de ocupação do solo urbano brasileiro. A preocupação do artigo está na possibilidade de trazer para regularidade as propriedades consideradas “informais” segundo a legislação vigente, tendo em vista que o direito de propriedade é também um direito fundamental, corolário do direito da moradia, ambos imprescindíveis para uma vida digna.
Benvenuti danni punitivi....o forse no!
Authors: Benatti Francesca
Published: July 2018

Questo articolo tratta della importanza della recente sentenza n 16601/2017 delle Sezioni Unite della Cassazione sta nell’aver affrontato il tema della riconoscibilità in Italia di sentenze che liquidano i danni punitivi, superando l’orientamento tradizionale  e fornendo indicazioni utili al legislatore per un suo eventuale intervento. L'articolo, dopo varie considerazioni, conclude, che la decisione delle Sezioni Unite costituisce un momento fondamentale di un percorso che è probabilmente solo all’inizio, chiarisce il dibattito e apre a possibili interventi del legislatore. E’ apprezzabile per equilibrio, moderazione e si pone come una delle migliori sentenze in materia non solo nel nostro ordinamento.  E’ condivisibile la soluzione di circoscrivere l’ambito del riconoscimento dei danni punitivi ed escluderne l’ingresso effettivo. Essa dimostra che solo quando il giudice non vuole essere “sovrano” , ma applica le leggi con puntuale adesione a al sistema si ha una vera e consapevole evoluzione del diritto. E allora diventa “sovrano”.
Who with Whom in Biofuel Policy? Coalitions in the Media Discourse on Liquid Biofuels in Germany
Authors: Puttkammer Judith , Grethe Harald
Published: July 2018

Politically driven, Germany’s biofuel sector has developed extremely fast in the last two decades. This development was favoured by a very successful presence of the beneficiaries of that support policy ‐ namely, the biofuel industry, German farmers and the agribusiness
‐ in the media.Amongst renewable energies, the use of biomass for fuel production is certainly one of the most controversially discussed forms. Although biofuels have been criticized for years, the EU and its member states persistently support this alternative fuel. The politically-driven
development of biofuels has, especially in Germany, grown very fast in the years 1995 to 2012. This study is interested in the discursive environment that contributed to this growth. By applying a media discourse analysis, we investigated the perception of biofuels, discourse coaltions, and
why some actors managed to dominate the public debate on biofuels.As our results show, biofuel supporters were most successful as  they found several advocates across different policy areas, made
use of the most significant frame within the debate, and used a variety of arguments in a broad, but still incorporated set of frames. 
Konfliktfeld ,,neue Gentechnik“: Regulierung landwirtschaftlicher Biotechnologien zwischen Innovation und Vorsorge
Authors: Friedrich Beate , Hackfort Sarah K.
Published: July 2018

Auf europäischer Ebene wird derzeit die Regulierung neuer molekularbiologischer Verfahren für die Landwirtschaft verhandelt. Mit diesen Biotechnologien können gezielt Mutationen herbeigeführt, Genabschnitte ausgeschnitten und Gene umgeschrieben werden. Die neuen
Techniken wecken Hoffnungen ‐ doch aufgrund der vielen offenen Fragen sollte die Regulierung landwirtschaftlicher Biotechnologien auf Vorsorge und Kennzeichnung setzen.
A 5-Year Experience of a Minimally Invasive Technique for Correction of Pectus Excavatum in Croatia
Authors: Žganjer Mirko , Župančić Božidar , Popović Ljiljana
Published: July 2018

The aim of this study was to assess the results of 5-year experience with minimally invasive operation without medial incision and resection cartilages for correction of pectum excavatum. From 2000 we made in our Hospital minimally invasive technique for the correction of pectus excavatum. 75 patients were treated by minimally invasive technique. A convex steel bar is inserted under the sternumtrough small bilateral Incisions. The steel bar is inserted with the convexity facing posteriorly, and when it is in position, the bar is turned over. After 2 years the bar is removed when permanent remolding has occurred. Initial excelent results were maintained in 54 patients (normal chest), good results in 16 (mild residual pectus) and poor in 5 (severe recurrence requiring further treatment). The mean follow-up since surgery were 3 months to 3 years. Average blood loss was 25 ml. Average length of hospital stay was 8 days. Patients returned to full activity after 2 month. Complications were pneumothorax in 12 patients, pneumonia in 6 patients and displacement of the steel barr requiring revision in 2 patients. Poor results occurred because steel bar was too soft in 3 patients, and soft sternum in 2 patients with Marfan’s syndrome. The minimally invesive technique is effective without cartilage incision and resection or sternal osteotomy.
Safety implications of plasma-induced effects in living cells – a review of in vitro and in vivo findings
Authors: Boehm Daniela , Bourke Paula
Published: July 2018

Cold atmospheric plasma is a versatile new tool in the biomedical field with applications ranging from disinfection, wound healing and tissue regeneration to blood coagulation, and cancer treatment. Along with improved insights into the underlying physical, chemical and biological principles, plasma medicine has also made important advances in the introduction into the clinic. However, in the absence of a standard plasma ‘dose’ definition, the diversity of the field poses certain difficulties in terms of comparability of plasma devices, treatment parameters and resulting biological effects, particularly with regards to the question of what constitutes a safe plasma application. Data from various in vitro cytotoxic and genotoxic studies along with in vivo findings from animal and human trials are reviewed to provide an overview of the current state of knowledge on the safety of plasma for biological applications. Treatment parameters employed in clinical studies were well tolerated but intense treatment conditions can also induce tissue damage or genotoxicity. There is a need identified to establish both guidelines and safety limits that ensure an absence of (long-term) side effects and to define treatments as safe for applications, where cell stimulation is desired, e.g. in wound healing, or those aimed at inducing cell death in the treatment of cancer.
Correlation between Travel Speed, Microstructure, Mechanical Properties and Wear Characteristics of Ni-Based Hardfaced Deposits over 316LN Austenitic Stainless Steel
Authors: Gnanasekaran S. , Padmanaban G. , Balasubramanian V. , Kumar Hemant , Albert Shaju K.
Published: July 2018

Laser hardfacing were produced using a high power Disk laser of 4 kW maximum power as a heat source to melt and bond the Colmonoy-5 powder on to AISI 316 LN stainless steel substrate. Significant difference in melting points between the austenitic stainless steel (ASS) substrate and Ni-based Colmonoy alloy results in substantial dilution of the hardfaced deposit from the substrate. In this present study, the effect of travel speed (TS) on microstructure, microhardness and wear characteristics laser hardfaced deposits were investigated. The phase constitution, microstructure and hardness of laser hardfaced deposits were examined by optical microscope, scanning electron microscope, energy dispersion spectroscopy, x-ray diffraction and Vickers hardness tester. The TS was varied between 300 and 500 mm/min. The other parameters such as, laser power, powder feed rate, and defocusing distance were kept constant. From this investigation, it is found that the deposit hardness increased from 750 HV to 800 HV with decreasing in TS. The TS increases, bead height decreased and dilution and depth of penetration increased. Due to higher TS the faster cooling rate takes place, it causes the cracking and porosity. Microhardness and wear resistance are slightly improved in the TS of 400 mm/min. The microstructures of deposit layer are composed of Ni-rich carbide, boride and silicide, this are the responsible for higher hardness and better wear resistance.
Minimization of Nonlinear Impairments and Its Impact on Transmission Performances of High-Capacity Long-Haul Optical Networks
Authors: Ali Farman , Khan Yousaf , Ali Amjad , Ahmad Gulzar
Published: July 2018

High-capacity and long-haul transmission gained great significance in modern communication networks. Optical fiber communication system is good enough to face the high demand of current telecom terrific. This paper will propound the theoretical model showing nonlinear factors which degrade the transmission performances of high-capacity long-haul network. The postulatory model will be validated using simulation of key nonlinear factors such as effective area, launch power, refractive index and fiber length. The transmission performance of the high-capacity long-haul optical network would be analyzed on the basis of some key parameters such as bit error rate and signal-to-noise ratio. Mitigation of nonlinear impairments shows significant impact on transmission performances of high-capacity long-haul optical networks.
Refractory hypoglycemia in a pediatric patient with desmoplastic small round cell tumor
Authors: Almaghraby Abdullah , Brickman Wendy J. , Goldstein Jeffery A. , Habiby Reema L.
Published: July 2018

Background

Tumor-induced hypoglycemia is a rare and serious complication that is usually a consequence of either excessive insulin secretion (insulinoma) or because of non-islet cell tumor hypoglycemia (NICTH). NICTH is a rare phenomenon seen most often in adult patients. It is associated with different tumor types. Here, we report the first case to the best of our knowledge in the literature of a pediatric patient with NICTH associated with desmoplastic small round cell tumor (DSRT).

Case presentation

This is a 15-year-old girl who presented with symptomatic hypoglycemia and abdominal mass. She required an intravenous glucose infusion rate as high as 9 mg/kg/min in addition to glucose containing oral supplements in order to maintain her blood glucose above 60 mg/dL. Computed tomography (CT) scan of the chest, abdomen and pelvis showed multiple hepatic lesions with an intraperitoneal soft tissue mass which subsequently was diagnosed as DSRT. When the blood glucose was 45 mg/dL, the insulin, growth hormone (GH) and insulin-like growth factor-1 (IGF-1) levels were suppressed with an appropriate elevation of cortisol. Subsequently, an insulin-like growth factor-2 (IGF-2) level was sent and the IGF-2:IGF-1 ratio was found to be elevated >10 consistent with NICTH. After the first dose of chemotherapy, hypoglycemia improved, and she was weaned off glucose containing fluids.

Conclusions

NICTH should be considered in all cancer patients regardless of their age with refractory hypoglycemia.
From nanoscopic to macroscopic photo-driven motion in azobenzene-containing materials
Authors: Oscurato Stefano L. , Salvatore Marcella , Maddalena Pasqualino , Ambrosio Antonio
Published: July 2018

The illumination of azobenzene molecules with UV/visible light efficiently converts the molecules between trans and cis isomerization states. Isomerization is accompanied by a large photo-induced molecular motion, which is able to significantly affect the physical and chemical properties of the materials in which they are incorporated. In some material systems, the nanoscopic structural movement of the isomerizing azobenzene molecules can be even propagated at macroscopic spatial scales. Reversible large-scale superficial photo-patterning and mechanical photo-actuation are efficiently achieved in azobenzene-containing glassy materials and liquid crystalline elastomers, respectively. This review covers several aspects related to the phenomenology and the applications of the light-driven macroscopic effects observed in these two classes of azomaterials, highlighting many of the possibilities they offer in different fields of science, like photonics, biology, surface engineering and robotics.
Nanoimmunotherapy – cloaked defenders to breach the cancer fortress
Authors: Kandasamy Gayathri , Annenkov Vadim , Krishnan Uma Maheswari
Published: July 2018

Cancer continues to be ranked among the top causes of mortality in the world despite the advances made in science and technology. The sub-par performance of cancer therapeutic strategies is due to the transformation of the cancer from a proliferating mass of cells into an impregnable fortress that manipulates and controls the microenvironment to prevent access to any potential cytotoxic factor as well as circumvent the innate immune surveillance processes. Recruitment of the native immune cells to selectively recognize and kill cancer cells can serve to augment the cytotoxic effects of conventional cancer therapeutic approaches. In addition to annihilation of the cancer cells, the induction of memory in the immune cells prevents the possibility of cancer recurrence. However, despite the apparent benefits of cancer immunotherapy, there are several pitfalls that need to be addressed in order to extend these benefits to the clinic. In this context, engineered nanostructured carrier systems can be effectively employed for an activation and priming of the host immune system selectively against the target cancer cells. This has led to the emergence of “nanoimmunotherapy” as an important therapeutic approach against cancer. The use of multi-functional nanomaterials in combination with immunotherapy offers possible solutions to overcome the current limitations in cancer therapy and represents the next generation of “smart therapeutics,” which forms the prime focus of discussion in this review.
La inclusión deportiva en Colombia: Una mirada desde los actores. Estudio de caso
Authors: Camargo Rojas Diana Alexandra , Forero Cárdenas Carmen Victoria
Published: July 2018

Las políticas públicas en Colombia presentan avances en su diseño e implementación en relación con discapacidad, específicamente las relacionadas con el derecho a la salud, la educación y el trabajo, en términos de inclusión. No obstante, en relación con la actividad física y el deporte se presentan deficiencias en su implementación. Por tanto, se hace necesario reconocer cuales son las percepciones de los deportistas con discapacidad, acerca del proceso de inclusión deportiva, los facilitadores, las barreras y las políticas públicas que se han diseñado e implementado. Desde el paradigma de las ciencias sociales, basado en la sociología del deporte y las políticas públicas,se realizó una revisión documental y entrevistas a profundidad a deportistas con discapacidad física de la Liga de la ciudad de Bogotá. Se identificó la presencia de políticas públicas a nivel nacional que permiten desarrollar acciones para la inclusión deportiva desde Coldeportes y el sistema paralímpico colombiano; sin embargo, para los deportistas, estas no son claras. La red de apoyo primaria para la inclusión deportiva continúa siendo la familia y las barreras están relacionadas con los imaginarios de la discapacidad, que generan barreras actitudinales desde la sociedad. En el deporte la exclusión por género y el poco apoyo de los medios de comunicación al deporte paralimpico, siguen estando presentes el país.
Accurate Genotype Imputation in Multiparental Populations from Low-Coverage Sequence
Authors: Zheng Chaozhi , Boer Martin P , van Eeuwijk Fred A
Published: July 2018

Many different types of multiparental populations have recently been produced to increase genetic diversity and resolution in QTL mapping. Low-coverage, genotyping-by-sequencing (GBS) technology has become a cost-effective tool in these populations, despite large amounts of missing data in offspring and founders. In this work, we present a general statistical framework for genotype imputation in such experimental crosses from low-coverage GBS data. Generalizing a previously developed hidden Markov model for calculating ancestral origins of offspring DNA, we present an imputation algorithm that does not require parental data and that is applicable to bi- and multiparental populations. Our imputation algorithm allows heterozygosity of parents and offspring as well as error correction in observed genotypes. Further, our approach can combine imputation and genotype calling from sequencing reads, and it also applies to called genotypes from SNP array data. We evaluate our imputation algorithm by simulated and real data sets in four different types of populations: the F2, the advanced intercross recombinant inbred lines, the multiparent advanced generation intercross, and the cross-pollinated population. Because our approach uses marker data and population design information efficiently, the comparisons with previous approaches show that our imputation is accurate at even very low (<1×) sequencing depth, in addition to having accurate genotype phasing and error detection.
Natural Variation in the Multidrug Efflux Pump SGE1 Underlies Ionic Liquid Tolerance in Yeast
Authors: Higgins Douglas A , Young Megan K M , Tremaine Mary , Sardi Maria , Fletcher Jenna M , Agnew Margaret , Liu Lisa , Dickinson Quinn , Peris David , Wrobel Russell L , Hittinger Chris Todd , Gasch Audrey P , Singer Steven W , Simmons Blake A , Landick Robert , Thelen Michael P , Sato Trey K
Published: July 2018

Imidazolium ionic liquids (IILs) have a range of biotechnological applications, including as pretreatment solvents that extract cellulose from plant biomass for microbial fermentation into sustainable bioenergy. However, residual levels of IILs, such as 1-ethyl-3-methylimidazolium chloride ([C2C1im]Cl), are toxic to biofuel-producing microbes, including the yeast Saccharomyces cerevisiae. S. cerevisiae strains isolated from diverse ecological niches differ in genomic sequence and in phenotypes potentially beneficial for industrial applications, including tolerance to inhibitory compounds present in hydrolyzed plant feedstocks. We evaluated >100 genome-sequenced S. cerevisiae strains for tolerance to [C2C1im]Cl and identified one strain with exceptional tolerance. By screening a library of genomic DNA fragments from the [C2C1im]Cl-tolerant strain for improved IIL tolerance, we identified SGE1, which encodes a plasma membrane multidrug efflux pump, and a previously uncharacterized gene that we named ionic liquid tolerance 1 (ILT1), which encodes a predicted membrane protein. Analyses of SGE1 sequences from our panel of S. cerevisiae strains together with growth phenotypes implicated two single nucleotide polymorphisms (SNPs) that associated with IIL tolerance and sensitivity. We confirmed these phenotypic effects by transferring the SGE1 SNPs into a [C2C1im]Cl-sensitive yeast strain using CRISPR/Cas9 genome editing. Further studies indicated that these SNPs affect Sge1 protein stability and cell surface localization, influencing the amount of toxic IILs that cells can pump out of the cytoplasm. Our results highlight the general potential for discovering useful biotechnological functions from untapped natural sequence variation and provide functional insight into emergent SGE1 alleles with reduced capacities to protect against IIL toxicity.
The Effects Of Self Esteem, Social Support, And Religious Orientation Toward Cyberbullying Intention On Adolescents At Senior High School
Authors: Kinanti Diah Roro , Hartati Netty
Published: July 2018

Cyberbullying intention has penetrated into adolescence and even in the school environment. Moreover, coupled with the widespread use of smartphones among adolescents. Number of Internet users in 2014 in Banten province and 3.3 million users in the age of 10-24 years of as much as 75.5%. Subjects of this study are 210 high school students in the area of Triguna Utama School. This study showed various results of cyberbullying intention variance proportion that affected by self-esteem, emotional support, instrumental support, informational support, companionship support, intrinsic orientation and ekstrinsic orientation which is 17,9% with the significant contribution variable as follows: companionship support, intrinsic orientation, and ekstrinsic orientation. DOI: 10.15408/tazkiya.v22i2.8400
Educational Recommender Systems: An Overview and Guidelines for Further Research and Development / Obrazovni sustavi preporučivanja: pregled stanja sa smjernicama za daljnja istraživanja i razvoj
Authors: Đurović Gordan , Holenko Dlab Martina , Hoić-Božić Nataša
Published: July 2018

AbstractEducational Recommender Systems (ERS) are increasingly used as tools to help students and teachers during the implementation of the learning process. The main difference between ERS and their commercial counterparts is in the pedagogical principles appropriate for the learning and teaching process. The differences in the educational methods used in a variety of educational situations, and their dependence on the field of study, set initial guidelines for ERS design. This paper reviews the evolution of ERS up to the currently achieved level of development and presents the basic techniques used in ERS design and the common problems they encounter in their work. Examples of classification of different ERS, according to their specific characteristics and basic approaches in their work, are presented. Based on this analysis, along with the training and upgrading of the existing algorithms, five specific areas in which future research and development can be expected are defined: construction of universal ERS, ERS intended primarily for teachers, ERS that links student achievements across different courses, ERS which take into account physical distance between students and use of ERS to motivate students to work continuously.Key words: educational environment; e-learning; learning outcomes; Web 2.0 tools---SažetakObrazovni sustavi preporučivanja (ERS) sve se više koriste kao alati za pomoć studentima i nastavnicima tijekom implementacije procesa učenja. Najvažnija razlika između ERS-ova i komercijalnih inačica sustava preporučivanja u pedagoškim je principima koji odgovaraju procesima učenja i poučavanja. Razlike u obrazovnim metodama koje se koriste u različitim obrazovnim situacijama, kao i njihova povezanost s područjem koje se uči, postavljaju polazne parametre za dizajniranje ERS-a. U ovom je članku dan pregled evolucije ERS-ova do trenutno postignutog nivoa razvoja, prikazane su osnovne metode na kojima su ERS-ovi dizajnirani, kao i uobičajeni problemi s kojima se ERS-ovi susreću u svojem radu. Na primjerima danas korištenih ERS-ova raspravljano je o klasifikaciji ERS-ova po njihovim posebnostima i osnovnim pristupima na kojima počiva njihov rad. Na temelju provedene analize, uz usavršavanje i nadograđivanje postojećih algoritama, određeno je pet područja u kojima se može očekivati buduće istraživanje i razvoj: izgradnja univerzalnog ERS-a, ERS-ovi namijenjeni primarno nastavnicima, ERS-ovi koji povezuju studentske uspjehe u različitim kolegijima, ERS-ovi koji uvažavaju fizičku udaljenost studenata i primjena ERS-ova za motiviranje studenata na kontinuirani rad. Ključne riječi: e-učenje; ishodi učenja; obrazovno okruženje; alati Weba 2.0.
Áreas de inundação no trecho paulista da bacia do Rio Paraíba do Sul e nascentes do Cadastro Ambiental Rural
Authors: Coutinho Marcos Pellegrini , Gonçalves Demerval Aparecido , Caram Rochane de Oliveira , Soares Paulo Valladares
Published: July 2018

Resumo A partir do conhecimento das áreas de risco de inundação urbana e do banco de dados do cadastro ambiental rural, que permite conhecer a localização das nascentes de cursos d’água, o artigo associa e avalia as áreas de risco e nascentes, propondo ações no âmbito das informações geradas. O estudo abrangeu 10 municípios da região do Vale do Paraíba, mapeados pelo Instituto de Pesquisas Tecnológicas (IPT), com risco de inundação e a situação das nascentes (áreas preservadas, consolidadas e a serem recompostas). Os resultados revelaram, para os municípios avaliados, que 10.324 nascentes foram cadastradas e, para todos os municípios, a quantidade de áreas preservadas é superior em relação às consolidadas. Além disso, há carência de projeto de recomposição da vegetação em nascentes de cursos d’água causadores de inundação nos municípios estudados, mesmo após alterações no Código Florestal. Tais informações podem ser utilizadas para subsidiar instituições locais, que atuam na revegetação de áreas desmatadas, e iniciativas que visem à mitigação de risco de inundação das áreas avaliadas.
Fire behaviour of non-welded concrete-filled-tube columns with strip connectors
Authors: Kang Hyun , Lee Jungmin , Kim Minsu , Heo In-Wook , Oh Jae Yuel , Kim Kang Su
Published: July 2018

Conventional concrete-filled-tube columns may have welding defects when welders of limited skill have been involved in their production; such defects could cause a rapid degradation of the columns’ strength during a fire. In the study reported in this paper, non-welded columns with mechanical strip connections were developed. Their structural performance, plus that of a typical welded column, was evaluated under both ambient and elevated temperatures. Axial loads were applied to all specimens; for fire resistance the axial load ratio was 40% and an ISO 834 standard fire curve was applied without fire protection. The non-welded columns with mechanical strip connections showed 15% higher strength under ambient temperature and resisted 40 min longer under elevated temperature compared to the typical welded column. Also, local buckling by compression was barely observed in the non-welded columns, whereas a large buckling was shown in the typical welded column under both ambient and elevated temperatures. It is concluded that non-welded columns with mechanical strip connections provide a viable way to avoid the welding problems of typical concrete-filled-tube columns, providing good performance under fire without fire protection.
Why We Can't Have Our Facts Back
Authors: Marres Noortje
Published: July 2018

How do we make the case for “knowledge democracy” in the face of the growing influence of right-wing figures and movements that denounce experts and expertise? While the threats to knowledge posed by these movements are real, it would be a mistake to return to a classic intellectual strategy––the politics of demarcation––in the face of this danger. Examining practical proposals for combatting fake news and opinion manipulation on the Internet, namely so-called "fact-checking" tools and services, I argue that they threaten to enroll us in a problematic normative project, one that aims to re-establish a hierarchy between knowledge and its presumed opposite, non-knowledge, or anti-knowledge. I list a number of shortcomings of this strategy. Most importantly, it distracts us from the role of technology in the crisis of public evidence in today's computationally-intensive societies. Social media are a truth-less public sphere by design. A politics of demarcation also puts us at risk of forgetting a key insight from the previous century that remains valid today: knowledge democracy is a re-constructive practice and an ideal. Instead of consolidating hierarchies of knowledge through facts that derive their authority form outside the public sphere, we need to recover the central role in public life of experimental facts: statements whose truth value is unstable. The experimental validation of public knowledge must happen in the public domain.
12% SDS-PAGE Western Blot v1
Authors: Basa Grace
Published: July 2018

This is the protocol for making and running a 12% SDS-PAGE Western blot. Protocol starts from pouring gels all the way to readingthe membrane.
Surgical treatment of advanced congenital kyphoscoliosis: A case report
Authors: Kosulin Artem V. , Elyakin Dmitriy V. , Dmitrieva Nadezhda N. , Abzalieva Alina D. , Blazhenko Aleksandra A. , Volchenko Lyubov V.
Published: July 2018

Clinical case of surgical treatment of advanced congenital kyphoscoliosis in 12 years old child is reported. Radiographs and CT at presentation failed to reveal the entire anomaly. By analysis of priorly made radiographs hemivertebra L1 was recognized. At genitourinary assessment L-shaped kidney was detected. A full-size 3D-printed model was used for surgical planning. Vertebral column resection as treatment option was discussed, but due to high neurologic complication rate this approach was refused. After preoperative 35 days halo-femoral traction anterior instrumented fusion was performed. Right ureter was stented for intraoperative urologic injury prevention. Scoliosis correction of 32% and kyphosis of 14% was achieved. 5 months later definitive posterior uninstrumented fusion was performed. Spinal deformities caused by vertebral malformations progress dramatically unless they are treated early. An advanced case is a clinical challenge because of technical difficulties and poor result. Vertebral column resection is a treatment option for severe kyphoscoliosis, but it’s indications should be strictly individualized. Preoperative halo-femoral traction is the most safe correction method in spinal deformity due to prolonged and gradual action. 3d-printed models are practical for surgical planning. The model may be used intraoperatively as a 3D-reference. In congenital scoliosis genitourinary system should be assessed meticulously, and urologist advice in relevant case is necessary.
Impact of Internal Factors on the Profitability of Banks: A Case of Commercial Banks in Bangladesh
Authors: Siddiqua Ayesha , Chowdhury A. N. M. Minhajul Haque , Chowdhury Abu Sayed Md. Mahmudul Haque , Mainuddin Md. , Rahman Md. Latifur
Published: July 2018

The internal factors of the bank have a great influence on the profitability of the banks. This study is an effort to disclose the effect of bank’s internal factors on return on equity (ROE), return on asset (ROA), and net interest margin (NIM) of ten selected commercial banks in Bangladesh for the period of 2011-2015. Researchers used descriptive statistics, correlation and regression analysis as statistics tools to find out the results. The findings from descriptive statistics indicate that Eastern Bank Limited was ranked first regarding profitability. The correlation test found that total equity to total asset ratio (TETA) and cost to income ratio (CIR) significantly affects the ROA whereas loan to deposit ratio had significant positive effect on the NIM of the banks. The regression analysis revealed that the independent variables of the banks were significant enough to explain the variation of the dependent variables (ROA, ROE, and NIM) of the study. 
JEL Classifications: G 21
MANAGERIAL ANALYSIS AS AN INSTRUMENT OF CRISIS MANAGEMENT
Authors: Alferov V. N.
Published: July 2018

Purpose: the main purpose of this article is to explore the possibility of applying management analysis as a mechanism for anti-crisis management and expanding tools for implementing crisis management in making effective management decisions. To achieve this goal, the following problems are solved in the article: determination of the place and content of management analysis in the system of economic analysis; identification of distinctive features, shortcomings and advantages in the conduct of financial and management analysis; generalization of features of application of methods of the administrative analysis; proposal and assessment of the place and functions of management analysis in the activities of the controlling service within the framework of crisis management in an economic entity.

Methods: this article is based on an interdisciplinary approach to the organization of crisis management in relation to the specifics of management accounting and analysis.

Results: currently, in the period of the constant appearance of external and internal factors of the crisis, the most important direction of stabilizing the financial situation of business structures is the development and effective use of anti-crisis management. This allows us to protect the vital interests of economic entities, the key element of which is stable activity and economic sustainable development. Ensuring the economic development of economic entities begins with the proper organization of crisis management and the effective use of its tools. One of the tools in conducting anti-crisis management is a financial analysis that has certain characteristics and disadvantages. The use of management analysis along with financial analysis will allow us to assess and prevent the emerging crisis phenomena in advance, stabilize the financial situation, identify factors and reserves for the anti-crisis development and subsequent economic sustainable development of economic entities.

 Conclusions and Relevance: the materials outlined in the article show the special role and importance of management analysis in the development of anti-crisis management in an economic entity, stabilization of its financial position and enhancement of its efficiency. To manage economic activity, management must investigate and monitor changes that occur not only in the external, but also in the internal environment of the organization. The possibility of using managerial analysis for managing economic activity, studying the results of financial and economic activities and controlling their changes, identifying negative internal factors, determining the advantages and disadvantages in order to ensure the adoption of sound and effective management decisions is analyzed.
Los acuerdos de refinanciación en las cooperativas
Authors: Torrubia Chalmeta Blanca
Published: July 2018

Las últimas reformas de la Ley concursal se han sucedido sin tiempo de valorar los efectos de las anteriores. Resulta así difícil extraer conclusiones fiables cuando se observa un determinado fenómeno, como es el caso del que analizaremos en este trabajo: las cooperativas han comenzado a acudir a la figura del acuerdo de refinanciación, como vía para superar su crisis, en el momento en que las sociedades capitalistas están abandonando su empleo. En el presente artículo, partiendo del marco normativo de los acuerdos de refinanciación, de sus efectos y del comportamiento de las cooperativas ante la crisis, se quiere hacer una valoración de este fenómeno. Para ello, se tendrá en cuenta el contenido de los acuerdos que las cooperativas han realizado y se han homologado judicialmente.Recibido: 5 marzo 2018Aceptado: 22 mayo 2018Publicación en línea: 24 julio 2018
Estimulação cerebral não invasiva excitatória sobre a atenção de adultos com sintomas do transtorno de déficit de atenção e hiperatividade
Authors: Dutra Tarcisio , Foerster Águida , Baltar Adriana , Gurgel Maria Lucia , Monte-Silva Katia
Published: July 2018

Objetivos: avaliar a atenção de adultos com sintomas de transtorno de déficit de atenção e hiperatividade (TDAH), quando submetidos a técnicas de estimulação cerebral não invasiva (ECNI) excitatória. Métodos: nesse estudo crossover 20 voluntários foram submetidos a uma sessão real e uma sham de Estimulação Magnética Transcraniana Repetitiva (EMTr) ou Estimulação Transcraniana por Corrente Contínua (ETCC). A EMTr (10Hz) foi aplicada no córtex dorsolateral esquerdo. A ETCC foi aplicada colocando-se o ânodo no mesmo local e cátodo na região supraorbital contralateral (1mA e 20 minutos). A avaliação foi realizada através de testes neuropsicológicos, considerando os desfechos: atenção focada e sustentada; amplitude atencional, manipulação mental e resistência à interferência. Resultados: observou-se que a ECNI excitatória exerceu efeito distinto entre os grupos, prejudicando o desempenho atencional dos adultos saudáveis e beneficiando os pacientes com TDAH. Destaca-se que em relação à estimulação sham o grupo controle aumentou o desempenho atencional de forma significativa, possivelmente decorrente do efeito de aprendizagem, enquanto o grupo com TDAH só obteve aumento no desempenho após a aplicação da estimulação real. Conclusão: os achados ratificam a compreensão que a ECNI excitatória pode contribuir para melhora cognitiva em adultos com TDAH e sugerem que processo inverso pode acontecer em relação aos saudáveis.
Por um diálogo plural e fecundo
Authors: Nunes César
Published: July 2018

Abrir uma edição inaugural de uma Revista eletrônica é, para todo professor, uma tarefa por demais honrosa. Pois significa socializar para dimensões inusitadas a produção criteriosa e fecunda de um determinado lugar, grupo ou conjunto de pesquisadores, colegas de ofício e companheiros e companheiras de ensino, pesquisa, atuação institucional e política no campo em questão. No presente caso, tenho a alegria e a honra de anunciar o número especial da Revista Digital PAIDEIA, concebida para tornar pública a dinâmica institucional e a fecunda produção do Grupo de Estudos e Pesquisas em Filosofia e Educação PAIDEIA, um dos destacados grupos de pesquisa do Programa de Pós-Graduação da Faculdade de Educação da Universidade Estadual de Campinas (UNICAMP).
A implantação oficial da Pedagogia Histórico-Crítica na rede pública do Paraná
Authors: Baczinski Alexandra Vanessa
Published: July 2018

O texto é resultado de estudo feito para a elaboração da dissertação de mestrado em educação, a qual partiu da problemática de como se deu a implantação oficial da pedagogia histórico-crítica no estado do Paraná, no períodode 1983 a 1994. O trabalho teve como ponto de partida o contexto político e econômico paranaense, contextualizando historicamente a organização da política educacional notadamente na esfera estadual, subsumida na dimensão nacional, no período de 1983 a 1996.
Uma leitura deleuziana da Estética Transcendental
Authors: Silva Vagner
Published: July 2018

Analisa-se o conceito de conceito, proposto por Deleuze/Guatarri e seus correlatos, averiguando-se a compatibilidade entre a proposta dos filósofos franceses a respeito do que é filosofia com a Estética Transcendental, parte da obra Crítica da razão pura, de Kant. Constata-se que, de acordo com os critérios propostos pelos pensadores franceses, é possível considerar o texto kantiano como o mais legítimo texto filosófico.
Las marcas de la formación virtual en la configuración de las identidades docentes
Authors: Marotias Ana Silvia , Marotias Laura Valeria , Finocchio Silvia
Published: July 2018

El propósito de este artículo es presentar y analizar los modos de construcción y reconstrucción de las subjetividades y las identidades docentes en espacios virtuales de formación, atendiendo a relatos e interacciones tanto formales como informales.
A educação e o prólogo da Genealogia da Moral de Nietzsche
Authors: Oliveira Fernando Bonadia de
Published: July 2018

Analisando-se a estrutura do “Prólogo” da Genealogia da Moral de Friederich Nietzsche, pretende-se compreender como este filósofo concebe a forma pela qual ele mesmo esteve, desde a infância, diante dos questionamentos sobre a origem dos valores morais. Trata-se de entender em que medida é possível aproveitar essa experiência de Nietzsche para definirmos uma tarefa para a Pedagogia, qual seja, a de questionar os valores morais existentes em seu interior. Todavia, menos do que definir propriamente tal tarefa, este trabalho consiste – em função de suas pequenas ambições – em um esboço inicial da questão.
Sensitivity of Airport Metal Detectors to Orthopaedic Implants
Authors: Kuczmarski Alexander S. , Harris Andrew P. , Gil Joseph A. , Owens Brett D.
Published: July 2018

* Patients frequently ask their orthopaedic surgeon if their implanted device will set off the metal detectors at the airport, but rarely get an evidence-based answer.

* Total shoulder, hip, and knee arthroplasty implants composed of cobalt-chromium alloys or titanium are the most likely implants to be detected.

* Stainless-steel implants in the foot and ankle, stainless-steel plates and screws in the upper extremity, and isolated stainless-steel nails, wires, and screws are the least likely implants to be detected.

* Contrary to previous findings, body mass index does not seem to impact the rate of detection.

* We recommend that surgeons provide their patients with medical documentation that can be presented to screeners and with evidence-based education based on the findings of this review and suggest that they avoid unnecessary alarm activation by non-orthopaedic metal (e.g. coins).
Pre-breeding in Passiflora subrotunda Mast.: Morphological and Reproductive Characterization at Different Light Levels
Authors: Souza Viviane de Oliveira , Souza Margarete Magalhães , Almeida Alex-Alan Furtado de , Barroso Joedson Pinto , Viana Alexandre Pio , Melo Cláusio Antônio Ferreira de
Published: July 2018

Passiflora are ornamental plants that are appreciated as part of outdoor decor, composing pergolas and gardens, as well as in interior ornamentation where species tolerant to environments with less light availability are used. The objective of this study was to evaluate the influence of different levels of light and pot types on morphological and reproductive characteristics in Passiflora subrotunda and to support genetic breeding programs of ornamental passifloras. The conditions of 75% and 100% light favored vegetative morphological characteristics through the time (105 days). Floral characteristics also presented higher values along increasing light levels. All qualitative characters related to flower and plant coloration did not vary among genotypes. The species possesses diurnal anthesis and flowers throughout the year. Plants cultivated in concrete pots showed greater growth and flower production. Pollen grains (PGs) are large, with an isopolar form, a small polar area, and a long aperture, and amylaceous. Percentage of viable PG was high: above 97% using Alexander solution and reaching up to 91% with fluorescein diacetate. Stigmas were partially receptive during the flower’s opening period. Percentage of self-compatibility was lower, based on the higher fertilization rate through cross-pollination. These information will be used in planning of ornamental Passiflora-breeding programs, assisting in the selection of characteristics and breeding methods.