bluuebunny/crossref_metadata_2025 huggingface dataset:
Efficient machine learning based surrogate models for surface kinetics by approximating the rates of the rate-determining steps
Authors: Döppel Felix , Votsmeier Martin
Published: March 2022

Machine learning based surrogate models that interpolate precomputed solutions of the rate equations can greatly accelerate simulations of catalytic systems. Established schemes for the construction of surrogate models depend on a logarithmic scaling of the source terms, which limits their application to cases where species are exclusively consumed or produced under all conditions of interest. We propose a new approach based on interpolating the forward- and reverse rates of the rate-determining reactions and thus overcoming this limitation. The new scheme is demonstrated using a surface reaction mechanism describing the oxidation of CO and H2 as well as the water gas shift reaction including 5 gas species, 9 surface species and 18 reversible reactions. Multivariate spline interpolation is used for a first evaluation of our approach. With the splines, the new method reproduces the source terms of CO with an error of 0.5 % which is 50 to 100 times more accurate than the established approaches of either mapping the source terms directly (49.9 % error) or mapping adsorption/desorption rates (23.7 % error). The true potential of the new approach develops in combination with machine learning techniques like neural networks. Even very small neural networks with a single hidden layer of 20 nodes yield an error of 0.35 %. This is about 200 times more accurate than the same neural networks used with the established approaches. Increasing the network size to still moderate 30 nodes in two hidden layers (2342 parameters in total) reduces the error to 0.0058 %. Besides the increased accuracy, the neural networks also outperform spline interpolation by at least an order of magnitude with respect to interpolation time, storage space and required amount of training data. Due to the extremely low errors achieved with moderate size neural networks and small training data sets, the proposed method based on mapping the rate-determining steps shows promise to scale to much larger and more complex reaction systems in catalysis and other fields like combustion, atmospheric chemistry or systems biology.
Generación de reglas de asociación para productos de retail utilizando el algoritmo FP-Growth paralelo
Authors: Pérez-Gómez Renato
Published: March 2022

Las organizaciones minoristas actuales tienen varias sucursales conectadas bajo el mismo sistema de gestión distribuido. Estos sistemas almacenan y registran la información de todas las transacciones dadas en las tiendas. Paralelamente, con el rápido crecimiento e implementación de las tecnologías de la información e Internet, la cantidad de datos generados en cada transacción o venta realizada es sustancial. Las técnicas de minería de datos tienen como objetivo identificar patrones y tendencias en una gran recopilación de datos. Su uso tiene un atractivo para los minoristas, ya que quieren convertir la gran cantidad de datos que tienen en información y conocimiento útiles. Una aplicación de minería de datos que atrae a los minoristas es el descubrimiento de reglas de asociación. El descubrimiento de estas reglas es la base de muchas decisiones comerciales, como el diseño de la canasta de productos, la elección de la estrategia de promoción y la combinación de productos. La intención de la investigación es la aplicación de las técnicas y metodologías de aprendizaje de asociación de reglas para la realidad de un comercio minorista con sucursales ubicadas en Lima. El conjunto de datos utilizado en esta investigación corresponderá a las transacciones realizadas con el tiempo para productos de consumo masivo.
What Can Innovation in Engineering Education Do for You as a Student and What can You Do as a Student for Innovation in Engineering Education?
Authors: Alario-Hoyos Carlos
Published: March 2022

Innovation in education in general and innovation in engineering education in particular must be supported by properly collected and analyzed data to guide decision-making processes. Today it is possible to collect data from many more stakeholders(not just students), and also to collect much more data from each stakeholder. Nevertheless, low-level data collected by monitoring the interactions of the multiple stakeholders with learning platforms and other computing systems must be transformed into meaningful high-level indicators and visualizations that guide decision-making processes. The aim of this paper is to discuss some notable trends in data-driven innovation in engineering education, including 1) improvement of educational content; 2) improvement of learners’ social interactions; 3) improvement of learners’ self-regulated learning skills; and 4) prediction of learners’ behavior. However, there are also significant risks associated with data collection and processing, such as privacy, transparency, biases, misinterpretations, etc., which must also be taken into account, and require creating specialized units and training the personnel in data management.
Red neuronal convolucional para la detección de aves exóticas en peligro de extinción
Authors: Narváez Guillermo Eduardo
Published: March 2022

En los últimos años, los índices de comercialización ilegal de animales se han incrementado debido a la falta de conciencia sobre el cuidado y la preservación de nuestro ecosistema. Entre los años 2000 y 2015, 67 749 animales silvestres fueron extraídos del Perú de manera ilegal. Entre ellos 29 591 eran aves exóticas (43 %), 26 951 anfibios (40 %), 8600 reptiles (13 %) y 2607 mamíferos (4 %); valorizados en mil dólares, aproximadamente. La propuesta para reducir significativamente estos actos ilícitos se basa en contar con un aplicativo que pueda identificar a las especies que se intentan comercializar ilegalmente. Dicho aplicativo hará uso de las arquitecturas de las redes neuronales convolucionales denominada VGGnet16, la cual permitirá identificar correctamente al animal. Se ha trabajado con una base de datos de animales reales obteniéndose una efectividad del 89 %.
Blockchain y smart contract para la trazabilidad de las donaciones
Authors: Espinoza Rossy , Ugaz Carlos
Published: March 2022

En la actualidad, una organización que administra donaciones tiene dificultades para controlar el flujo de ingreso y salida de donativos, dificultando la trazabilidad de estos. En esta investigación se propone un sistema basado en blockchain que garantice la trazabilidad de los donativos desde su origen hasta su destino, utilizando un protocolo de consenso proof of work y un contrato inteligente (smart contract) con funciones específicas.
Aplicación en realidad virtual para concientización del peligro de sobreexposición a la radiación UV
Authors: Vargas-Solís Edgard Javier Hernán
Published: March 2022

La presente investigación busca concientizar a la población acerca de la elevada radiación UV registrada en nuestro país, a partir del desarrollo de una aplicación en realidad virtual. Este estudio evaluará el desempeño de dicha aplicación a través de un cuestionario.
Ambulancia McQueen: optimización de rutas para ambulancias a partir de la distancia entre el accidente y el centro de salud
Authors: Ríos Alarcón Alexia Shariann , Mariños Ore Carlos Felipe , Nepo Gamero Andrea Isabel , Cárdenas Zúñiga Juan David Amado , Ayma Quirita Víctor Andrés
Published: March 2022

Actualmente el transporte prehospitalario, como el que brindan las ambulancias para la atención médica de emergencia o soporte para atención primaria, enfrenta un gran problema en Lima: el tráfico, el cual además se ve afectado por el tiempo que transcurre desde que ocurre la emergencia hasta que el centro de salud envía una ambulancia para su atención. En ese sentido, es de suma importancia optimizar el tiempo de respuesta de este proceso para que la atención médica se brinde lo más rápido posible, ya que, durante una emergencia, el tiempo de atención es crucial. Por ello, este trabajo propone una metodología para optimizar la ruta y el tiempo de envío de una ambulancia para la atención de la emergencia tomando en consideración la distancia entre el centro de salud y el lugar de ocurrencia de la emergencia, específicamente, centrando nuestro piloto en el distrito de San Borja. Por otro lado, desde el punto de vista del paciente, se busca que este pueda pedir y acceder a una ambulancia lo más pronto posible a través de una única plataforma. Para ello se ha diseñado un programa de código abierto, codificado en Python con las librerías OSMnx y Networks, el cual hace uso además del algoritmo de Dijkstra para la optimización de la ruta a seguir hasta el lugar de la emergencia. Las pruebas experimentales pudieron validar que mediante este proceso se logró optimizar el tiempo de acción requerido para la atención de estos casos al facilitar la logística necesaria para enviar las ambulancias, considerando, asimismo, que este tiempo ahorrado podría hacer posible salvar la vida de las personas involucradas en tales eventos.
The EU Trustworthy Artificial Intelligence: How the EU Wants to Regulate the Artificial Intelligence Practices
Authors: Rodríguez Cuadros Miguel Adolfo
Published: March 2022

The European Union (EU) recently proposed in April 2021 an Artificial Intelligence legal framework. The EU highlights the advantages of using Artificial Intelligence (AI) especially in prediction, optimizing operations, resource allocation and personalizing service delivery. Nevertheless, the EU considers that AI might bring new risks and negative consequences for individuals and society when an AI system violates the EU values and fundamental rights. This paper explains how the EU is proposing a legal framework for trustworthy AI. Tech or nontech companies and professionals should know what kind of AI applications and practices might be prohibited or restricted within the EU. More specifically, this paper focuses on what type of AI system can be considered unacceptable risk, high or low risk AI.
Comparación de técnicas de procesamiento de imágenes para la detección de fisuras en pinturas al óleo
Authors: Rucoba Calderón Carla Valeria
Published: March 2022

En el presente estudio se aplicaron tres técnicas de procesamiento de imágenes a pinturas al óleo digitalizadas con el objetivo de detectar el craquelado de estas y representarlo en mapas binarios, que posteriormente sean comparados. Las tres técnicas aplicadas fueron: filtro alargado orientado, filtro morfológico top-hat y algoritmo K-SVD. La primera técnica mostró la capacidad de detectar la continuidad de las fisuras, pero tuvo problemas en descartar píxeles aislados; la segunda técnica detectó continuidad y representó la anchura de las fisuras correctamente; sin embargo, no trabajó correctamente en zonas suavizadas y con una menor iluminación; y la tercera técnica identificó sin problema el craquelado en zonas oscuras y suavizadas. Es así que los resultados demostraron que las técnicas son complementarias entre sí.
Monitoreo basado en visión computacional de aves en peligro de extinción de la reserva Pantanos de Villa
Authors: Sánchez Huamán Luis Giancarlo
Published: March 2022

Los gobiernos, junto con numerosas organizaciones de conservación, trabajan para proteger las aves, en especial en las reservas naturales como los Pantanos de Villa, Perú. Sin embargo, sus poblaciones están descendiendo a escala global, fundamentalmente por causa de la contaminación. Por ello, es necesario realizar censos permanentes para monitorear la cantidad de aves, de manera ágil y a bajo costo, sin requerir la intervención de un experto humano. El presente trabajo propone un sistema de monitoreo formado por un modelo de detección utilizando Mask R-CNN con un dataset público Open Images Dataset V6 y un clasificador Deep Convolutional Neuronal Network con un dataset de cuatro especies de aves de la reserva de Pantanos de Villa. El sistema se basa en imágenes capturadas por los propios trabajadores, donde se realice la detección y clasificación. Tras varias evaluaciones diarias se determinará la población existente de aves y, cuando se presente una disminución, la reserva tomará acciones. El sistema propuesto logró detectar y clasificar las especies de aves para la realización del monitoreo con una exactitud de 82,49 % logrando mejorar los valores obtenidos previamente empleando únicamente el clasificador.
Potential of the Aarhus Convention for the Establishment of an International Legal Mechanosm for the Protection of Lake Baikal
Authors:   Irkutsk State University, Shornikov D.
Published: March 2022

As part of the project to build the concept of international legal protection, Lake Baikal, supported by the Russian Foundation for Basic Research, considered the key provisions of the 1998 United Nations Economic Commission for Europe Convention on Access to Information, Public Participation in Decision-making and Access to Justice in Environmental Matters, the so-called Aarhus Convention, and the Protocol on Pollutant Release and Transfer Registers (PRTRs) 2003, bearing in mind, above all, their potential for developing the mechanism of international legal protection of Lake Baikal. It was analyzed the experience of the Republic of Kazakhstan and the Republic of Belarus in implementing the provisions of these international instruments into national legislation, as well as the creation and development of the Aarhus Centers in these countries of the post-Soviet space. The experience and current position of the Russian Federation on the perception of the provisions and mechanisms of the Aarhus Convention in the national legal system and law enforcement practices are highlighted. The conclusion that the use of conventional mechanisms for access to information, public participation in decision-making and access to justice in environmental matters enshrined in these international instruments to preserve the unique ecosystem of the Lake Baikal World Heritage Site is justified.
Barriers to the use of mental health services by Syrian refugees in Jordan: a qualitative study
Authors: Bawadi Hala , Al-Hamdan Zaid , Khader Yousef , Aldalaykeh Mohammed
Published: March 2022

Background: More than 650 000 Syrian refugees are hosted in Jordan. Refugees are at high risk of mental health problems. Aims: To explore the perspectives of Syrian refugees and their host communities and community leaders in Jordan on barriers and facilitators to the use of mental health services by Syrian refugees. Methods: A qualitative descriptive design was used to collect data through individual, semistructured interviews conducted between May and December 2019 in Jordan. A purposive sample was recruited from different sites. Results: Twenty-four individual interviews were conducted: 16 for the clients and 8 for the community leaders. Three themes emerged as barriers to accessing mental health services: (1) lack of awareness of mental illness and available services; (2) availability, accessibility and affordability of mental health services; and (3) stigma and social discrimination. Findings show that respondents had low mental health literacy levels. Conclusion: Policy-makers, care providers and decision-makers should take the findings of this study into consideration by facilitating the use of mental health services through awareness-raising about mental illness and the provision of services at primary health care centres. Making the service available near to the people who require it and incorporating mental health services into a broad-based community environment such as schools, primary health centres, or case management system are recommended as a common strategy that could help address refugee needs.
Sigale-gale samosir: from the sacred to the secular | Sigale-gale samosir: dari yang sakral menjadi sekular
Authors:   Institut Seni Indonesia Padangpanjang, Sumatera Barat, Minawati Rosta , Alamo Enrico ,   Institut Seni Indonesia Padangpanjang, Sumatera Barat
Published: March 2022

Sigale-gale is a life-sized wooden puppet carved in the likeness of a human male. It is used during burial rituals and in modern Sigale-gale dance performances in the Toba Batak community, Samosir, North Sumatra. The traditional myth of sigale-gale has become folklore which depicts the making of a wooden statue in human form given to Raja Rahat who is ill because his favorite son Manggale died in the battle. The sigale-gale is used by the community as well in funeral ceremonies for the dead who have died childless. In contemporary practice sigale-gale has been reconceived as public performance mostly for tourists. The sigale-gale thus now functions differently socially and culturally, moving from the mythological towards the worldly. The sigale-gale dance was originally only accompanied by the music of sordam but mostly now by a mixed ensemble comprised of taganing, gong, and suling. A performance can include five to seven dancers (panortor). Sigale-gale also vary in size from human dimensions as well as smaller or even bigger. Sigale-gale in its new forms represents an effort to sustain the cultural values of the Toba Batak. Patung sigale-gale terbuat dari kayu yang dipahat menyerupai manusia (laki-laki) digunakan saat ritual pemakaman dan dalam pertunjukan tari sigale-gale baru di masyarakat Batak Toba, Samosir, Sumatera Utara. Mitos keberadaan sigale-gale menjadi folklore yang menceritakan pembuatan patung kayu menyerupai manusia dipersembahkan kepada Raja Rahat yang sakit karena anaknya tewas di medan pertempuran. Sigale-gale digunakan pada upacara kematian yang tidak memiliki keturunan. Dalam perkembangannya, sigale-gale menjadi seni pertunjukan untuk menghibur wisatawan. Fungsi sigale-gale secara sosial budaya menjadi berbeda, yakni dari sakral ke profan. Awalnya sigale-gale hanya diiringi musik Sordam dan Sabangunan, tetapi di masa kini pertunjukan sigale-gale diiringi musik gondang, gong dan suling. Pertunjukan sigale-gale terdapat panortor lima sampai tujuh orang. Ukuran patung sigale-gale bervariasi, ada yang tinggi seukuran manusia ada juga yang memiliki ukuran tubuh lebih kecil ataupun lebih besar. Unsur pertunjukan terdiri dari: Sigale-gale, musik dan tor-tor (tari). Sigale-gale dalam bentuk baru merupakan upaya pelestarian nilai-nilai budaya masyarakat Batak Toba.
Frankismo berantiarra eta lehenengo estatu demokratikoa jarduera armatuaren aurka (1968-1979): jarraipenak eta aldaketak
Authors: Uriarte Cuadrado Alexander
Published: March 2022

Frankismoaren ondoren, demokratikotzat hartu ziren lehenengo hauteskundeak egin ziren 1977ko ekainean. Eratutako lehenengo estatu demokratikoak kudeatu behar izan zuen frankismoak herentzian utzitako jarduera armatuaren arazoa. Emandako erantzuna enfrentamenduarena izan zen; hain zuzen, erregimen diktatorialak emandako berdintsua. Lan honetan, gainetik bada ere, frankismo berantiarraren diktadurak zein geroko estatu demokratikoak erabili zituzten zenbait jardunbide eta diskurtso argituko dira, baita horietan izandako jarraipenak eta aldaketak ere trantsizioaren garai hartan.
Hegoaldeko Haur eta Lehen Hezkuntzako irakasleen usteak eleaniztasunari buruz
Authors: Gartziarena San Policarpo Mikel , Altuna Jon
Published: March 2022

Eleaniztasuna garrantzi handiko gertakaria da gurean. Gizartearen eta bereziki hezkuntza-komunitatearen ardura nagusietakoa da, euskararen transmisioaz gaindi, gainerako curriculum-hizkuntzen kalitatezko irakaskuntza bermatzea. Ikerketa honen helbururik behinena da Hegoaldeko Haur eta Lehen Hezkuntzako irakasleen eleaniztasunari buruzko usteak ezagutzea. Izan ere, irakasleen usteetan sakontzeak hizkuntzei atxikitako juzguak eta irakas-jardunak hobeki ulertzea dakar. Uste horiek ezagutzea helburu, online galdetegia diseinatu eta Hegoaldeko lau lurraldeotako 418 irakasleren datu kuantitatiboak jaso dira. Emaitzek islatzen dute irakasleek uste positiboak dituztela eleaniztasunari buruz, eleaniztasuna onura gisa hautematen dutela eta euskararen garrantzia aintzatesten dutela. Ikerketa-emaitzek ondorioztatzen dute, oro har, irakasleek uste positiboak dituztela eleaniztasunari buruz eta ikasle eleaniztunak hizkuntza-ikasle hobeak kontsideratzen dituztela, bazterturik erabat eleaniztasuna arazo-iturri izan daitekeen ustea; edonola ere, Haur eta Lehen Hezkuntzako irakasleek sakon errotuta dute honako uste hau: hizkuntzak, zenbat eta lehenago, orduan eta hobeto.
Portaera berritzailearen koxka ETE-etan: berrikuntza-taldeak
Authors: Martínez Moreno Edurne , Mindeguia Petrirena Rosa , Díaz Gorriti Virginia , Da Costa Silvia , Larruskain Mandiola Olaia
Published: March 2022

Merkatu globalizatu batean gertatutako krisi ekonomikoen aurrean, enpresa txiki eta ertainen (ETE) berrikuntza funtsezkoa da haien biziraupenerako. Ikerketa honen helburu nagusia da ETE-etan jokabide berritzailea errazten eta zailtzen duten faktoreen eragina ikertzea, berrikuntza-taldeak eta haien ingurunea aztertuz. Hurbilketa metodologiko misto baten bidez, maila anitzeko eta luzetarako ikuspegiarekin, kultura berritzaile eta parte-hartzaileek, lidergo eraldatzaileek eta plangintzek jokabide berritzaileak sustatzen ote zituzten aztertu zen. Lagina, zerbitzuen eta ekoizpenaren sektoreetako jarduerak dituzten sektore publikoko zein pribatuko 8 erakundetako 14 taldek osatu zuten. Gure emaitzek iradokitzen dute kultura berritzailea funtsezkoa dela langileen jokabide berritzailea sustatzeko, betiere erabakietan parte hartzen badute. Lidergo eraldatzaileak hasierako faseko jardueren plangintzaren bidez sustatuko du soilik talde-testuinguruko jokabide berritzailea. Berrikuntza-ikuskera desberdina da zuzendarientzat eta langileentzat, baina berrikuntza-taldeen bidez konpon daiteke.
Ekintza kolektiboa euskal protesta-zikloan: «Lizarra-Garazi»ko kasuaren azterketa (1995-2000)
Authors: Sierra Zapirain Galder
Published: March 2022

Aldaketa-prozesuak protesta-mugimenduen ekintza kolektiboari lotuta agertu ohi dira. Gure aztergaiari dagokionez, 1990eko hamarkadaren bigarren erdialdean euskal protesta-zikloaren areagotze nabarmena gertatu zen, autoritateen eta lehiatzaileen arteko ekintza kolektiboa zabalduz. Artikulu honen helburua da areagotze horretan parte hartu zuten gertakariak eta haien ondorioak azaltzea. Horretarako, gatazka konplexuen ikerketetan Doug McAdamek, Sidney Tarrowek eta Charles Tillyk baliatutako mekanismo eta prozesuak erabiliko ditugu. Zentzu horretan, liskarraldi mota ezberdinetan parte hartzen duten bitarteko horiek Lizarra-Garaziko Akordioak ezaugarritu zuen epealdian (1995-2000) ere funtsezko papera jokatu zutela ikusi ahal izango dugu; bai ekintza kolektiboaren garapenean, bai politika instituzionaletan emandako aldaketetan. Aldaketa horiek, ordea, mugatuak izan ziren, eta inplikatutako eragileek eraldaketa-prozesuak ulertzeko baliatu zituzten paradigma ezberdinetan aurki dezakegu haien ezintasun nagusietako bat.
Changes in the biochemical parameters of soybeans depending on the growing conditions
Authors: Kozak D. K. , Ivachenko L. E. , Golokhvast K. S.
Published: March 2022

The results of the analysis of changes in biochemical parameters of soybeans depending on growing conditions are presented. The object of the study was samples of soybean (Glycine max (L.) Merr) of the Lydia variety and wild soybean (Glycine soja Sieb. & Zucc.) forms of KA-1344 grown on natural soils (control and with a high content of heavy metals). The analysis was carried out in leaves, stems, roots, flowers and seeds of cultivated and wild soybeans in the phase of the first triple leaf, flowering and fruiting. The content of malonic dialdehyde and the specific activity of acid phosphatase were determined by spectrophotometric method, the activity of peroxidase – by colorimetric method, the content of zinc, copper and lead – by atomic absorption. Electrophoretic spectra of acid phosphatase were detected by electrophoresis on columns of 7.5% polyacrylamide gel. Identification of zones with enzymatic activity on the gel was carried out by appropriate histochemical methods. It has been established that the cultivation of soybeans on soil with a high content of zinc, copper and lead leads to their accumulation in the organs of soybeans. The highest content of the studied metals is found in the roots. Growing soybeans on soil with a high content of zinc, copper and lead led to an increase in the specific activity of peroxidase in its organs. At the same time, the content of malonic dialdehyde in cultivated soybeans significantly increased only in stems during the phase of the first triple leaf and in roots during the flowering phase, and in wild soybeans in leaves, stems and roots during the phase of the first triple leaf and in stems during the flowering phase. It has been revealed that the flowers have the maximum specific activity of acid phosphatase. Cultivated soybeans, under conditions of increased zinc, copper and lead content in the soil, were characterized by an increase in the specific activity of acid phosphatase and the appearance of new multiple forms. For wild soybeans, in general, there was a decrease in the specific activity of acid phosphatase and an increase in the number of multiple forms of the enzyme.
Adaptación y validación de la prueba de detección de consumo de alcohol, tabaco y sustancias (ASSIST) en adolescentes mexicanos de una población semirrural
Authors: Casas Muñoz Abigail , Velasco Rojano Ángel Eduardo , Loredo Abdalá Arturo
Published: March 2022

Introduction: the onset of substance use in adolescence could generate negative consequences in the future; for this reason it is recommended to have internationally standardized surveillance systems in adolescents, especially the most vulnerable without easy access to health or protection services such as those in a semi-rural context. Objective: to adapt and validate the ASSIST (Detection of Alcohol, Tobacco and Substance Consumption) screening test and to determine the prevalence of consumption in a sample of Mexican adolescents from a semi-rural community. Method: cross-sectional study in two public schools of the municipality of Malinalco, Mexico, the adapted version of ASSIST was applied with 8 reagents that identifies 10 substances and the need for brief psychotherapy, to adolescents from 11 to 19 years. Results: 229 students participated, 61% women, 19.3% secondary, 76.8% high school and 3.9% out of school. The test had adequate reliability (Cronbach’s Alpha = .84) and a correctly adjusted factorial structure [X2(7) = 3.18, p = .86, CFI = 1, RMSEA = 0]. The prevalence of consumption were Tobacco 27%, Alcohol 50%, Cannabis 13%, Cocaine 8%, Stimulants 6%, Inhalants 2%, Tranquilizers 3%, Hallucinogens 4%, Opiates 2% and Others 2%; of these 30% were in high school and 17% required brief psychotherapy. Discussion and conclusions: the version adapted with culturally relevant content is reliable and valid, with a structure that coincides with the original, can be used in research, diagnosis and intervention to generate information that helps plan strategies to improve the health of the adolescent population.
“What Will It Be Next?”: The Process of ‘Dramatic Child’ in Edward Bond’s Eleven Vest
Authors: ADA Uğur , PARLAK Erdinç
Published: March 2022

In this study, the concept of ‘Dramatic Child’ will be examined within the framework of the play, Eleven Vests written by Edward Bond, one of the prominent playwrights of post-war British theatre. The concept put forward by the playwright comes to the fore as a process that reveals the conflicts experienced by children as individuals in society − structured by adults − with their environment. The process, which is fictionalized through the main character’s (Student) experiences during his training at school and in the army, scrutinizes the situations in which children are isolated, marginalized and eventually become perpetrators/victims of violence in today's world which does not allow them to realize themselves. Reflecting the insensitive and hypocritical attitudes of adults, the playwright criticizes the social order which converts children into passive individuals and thus makes them part of an order dominated by unilateral consensus. Despite the fact that adults failing to fulfill their responsibilities, the playwright avoids presenting a hopeless message for the future. At the end of the play, Student, now an adult, reflects the need to create a new language of his own and an order in which the meaning of humanity can be sustained. In this study, it is aimed to analyze this creation process within the framework of ‘Dramatic Child’ conceptualized by the playwright.
Nodular Melanoma: A Review of Pathogenesis, Presentation, Diagnosis, and Treatment
Authors: Hernandez Loren E , Frech Fabio Stefano , Mohsin Noreen , Dreyfuss Isabella , Nouri Keyvan
Published: March 2022

Nodular melanoma is the second most common subtype of melanoma. Unlike other subtypes, nodular melanoma is characterized by early vertical growth rather than the typical initial radial growth of most melanomas. As a result, nodular melanoma presents clinically in a more aggressive phenotype. Given its more aggressive nature and intrinsic ability to mimic benign lesions, a modified acronym has been developed to allow clinicians to better evaluate, diagnose and treat nodular melanoma in earlier stages. Surgical excision with wide margins is the gold standard of nodular melanoma therapy; however, an emphasis in early detection, diagnosis, staging, and treatment needs to be emphasized among clinicians due to its dismal prognosis in later stages, as compared to other subtypes. A better understanding of the molecular pathophysiology that allows nodular melanoma to act aggressively very early in diagnosis is necessary for the development of therapeutics that may effectively target lesions in more advanced stages.
Tendências Políticas em Puebla
Authors: Christo Alberto Libânio
Published: March 2022

Não é fácil falar das tendências políticas intrínsecas à reunião episcopal de Puebla. Além de certo tabu eclesial (ou eclesiástico) sobre o tema, muitos bispos têm a pretensão de não «fazerem política». É claro que, partidariamente, nossos pastores não fazem política. Porém, esta é uma regra com muitas exceções: por vezes, bispos apóiam publicamente determinados candidatos e o Papa Paulo VI não relutou em pedir votos para a Democracia Cristã quando pressentiu que a prefeitura de Roma cairia em mãos do Partido Comunista, o que veio a ocorrer...
Constitutionalisation and deconstitutionalisation of administrative law in view of Europeanisation and emancipation
Authors: Barbosa Jeferson Ferreira , Wollenschläger Ferdinand
Published: March 2022

A constitucionalização constitui um fenomeno comum das ordens jurídicas administrativas europeias, e também o direito administrativo da UE é cada vez mais influenciado pelo seu quadro constitucional, nomeadamente após a entrada em vigor da Carta dos Direitos Fundamentais da EU, que garante explicitamente o direito a uma boa administração. Com referência ao direito administrativo alemão, provavelmente o sistema de direito administrativo mais constitucionalizado, culminando no entendimento de Fritz Werner de "Verwaltungsrecht als konkretisiertes Verfassungsrecht" ("direito administrativo como direito constitucional concretizado"), o artigo, num primeiro passo, não só aprofunda o fenómeno da constitucionalização, mas também qualifica a tese de constitucionalização generalizada. Esta última foi além disso questionada por duas megatendências com impacto em todas as ordens jurídicas administrativas europeias, nomeadamente a sua europeização e a sua alegada emancipação da Constituição. Se isto significa uma desconstitucionalização do direito administrativo e como estas tendências podem ser conciliadas, será discutido em outras partes do artigo. Os conhecimentos gerados pela utilização, nomeadamente, do exemplo do direito administrativo alemão são de relevância pan-europeia e podem servir como instrumento de análise numa perspectiva comparativa e tendo em vista o futuro desenvolvimento do direito administrativo da EU.
Paternalismo no Direito Privado
Authors: Neuner Jörg
Published: March 2022

O paternalismo está profundamente arraigado em nosso ordenamento jurídico, em especial no Direito Privado. Ele restringe a autonomia privada de forma “branda”, “dura” e “mista” (junto com outros motivos) e, por isso, levanta constantemente, em diversos contextos, a tradicional questão da legitimidade.
Nota Editorial (Inglês)
Authors: Sartori Paola Mondardo
Published: March 2022

Nota Editorial (Inglês)
SISTEMA PENAL DO INIMIGO
Authors: Nadim de Lazari Rafael José , Andreus Gama Alison
Published: March 2022

O presente artigo realiza o papel de um diagnóstico jurídico-científico, pois busca identificar dentro do sistema penal brasileiro aproximações legislativas e práticas para com a teoria do direito penal do inimigo. Ao final, não será apresentada propriamente uma solução hipotética para resolver o problema oriundo desta aproximação entre os eixos apresentados no desenvolvimento, pois tal tarefa se mostra descabida para os fins de um simples artigo. O que se pretende, sim, é uma satisfatória identificação dos pontos em que o discurso do direito penal do inimigo se confunde com a realidade observada no sistema penal brasileiro, tendo como premissa geral a elaboração do diagnóstico ao final. Para possibilitar tal elaboração, será utilizado o método indutivo, tendo como fonte a doutrina penal brasileira e a própria teoria do direito penal do inimigo.
APPLICATION OF THE GENERALIZED ELECTROMECHANICAL CONVERTER THEORY TO ANALYSIS OF THE STATIC CHARACTERISTICS OF AN INDUCTION MOTOR
Authors:   Kryvyi Rih National University, Tytiuk V. , Mikhieiev D. ,   Kryvyi Rih National University, Tolmachov S. ,   Kryvyi Rih National University, Danyleiko O. ,   Kryvyi Rih National University
Published: March 2022

Purpose. The work is devoted to the development of a closed-loop control system of hydraulic transport system with pressure stabilization and its research on a mathematical model. Originality. The expediency of application of a closed-loop control system of electric water transport system with pressure stabilization as the most promising way of resource saving in the operation of pumping complexes is substantiated. The realization of the closed-loop pressure stabilization system using a discrete program regulator is proposed. The studies of parametric sensitivity of the closedloop pressure stabilization system have confirmed the high robustness of the proposed solution. Methodology. General methods of physics, hydraulics, mathematical analysis and computational mathematics were used to solve the tasks. Numerical solution of mathematical model equations and visualization of obtained results were performed in MATLAB®/Simulink environment. Results. The expediency of using closed-loop control systems of pumping units with pressure stabilization as the most promising way of resource saving in the operation of pumping complexes is substantiated. The impossibility of implementing the pressure stabilization system based on the classical PID controller is shown, which is caused by the influence of wave processes in the pipeline system with distributed parameters. The closed-loop pressure stabilization system with the use of a discrete program regulator is realized, its stability and robustness in a wide range of changes in the regulator parameters is shown. Practical value. The possibility of implementing a closed-loop pressure stabilization system of electric hydrotransport system has been substantiated; a method of calculating the discrete program pressure regulator based on the regression analysis of the results of mathematical modeling has been proposed. Figures 12, tables 2, references 9.
Influence of cold deformation and heat treatment on structure, texture and properties of titanium pseudo-β-alloy
Authors:   Moscow Aviation Institute (National Research University), Kollerov M. Yu. , Afonina M. B. ,   Moscow Aviation Institute (National Research University), Neiman A. P. Neiman ,   Moscow Aviation Institute (National Research University), Zainetdinova G. T. ,   Moscow Aviation Institute (National Research University)
Published: March 2022

The effect of cold plastic deformation and heat treatment on the phase composition, structure, texture, and mechanical properties of sheets of pseudo-β-titanium alloy VT35 has been studied. It has been established that after cold rolling of sheet semi-finished products, a multicomponent texture (111) + (112) + (100) is formed, which during subsequent heat treatment is transformed into a similar texture but with a lower degree of texturing. A generalized diagram of phase and structural transformations with temperature-time conditions for the onset of polygonization, recrystallization, and decay of the β-phase was constructed. It is shown that, subject to the sequence and kinetics of the processes occurring during heat treatment, it is possible to form a structure of various types in the alloy, which makes possible to change its technological and mechanical properties in a wide range.
Molecular Subtypes of High-Grade Neuroendocrine Carcinoma (HGNEC): What is YAP1-Positive HGNEC?
Authors: Kawai Hitomi , Matsuoka Ryouta , Ito Takeshi , Matsubara Daisuke
Published: March 2022

Small cell lung cancer (SCLC) subtype classification, based on high-level expression of key transcriptional regulators; ASCL1 (SCLC-A), NEUROD1 (SCLC-N), POU2F3 (SCLC-P), and YAP1 (SCLC-Y), has recently been proposed. YAP1 (and POU2F3) has attracted attention as an important factor for non-neuroendocrine (non-NE) phenotypic subtyping of SCLC. However, subsequent studies reported that YAP1 expression alone cannot define a single group in primary SCLC, which makes it difficult to understand what SCLC-Y is by focusing only on SCLC. In this review, we concluded that YAP1 is an essential anti-neuroendocrine factor in both SCLC and non-small cell lung cancer (NSCLC) based on previous studies, including our own analysis of the cell lines and primary tumors of SCLC and NSCLC. The classification of SCLC-Y is a concept mainly established from the analysis of cell lines, and SCLC-Y cell lines correspond to “variant type” SCLC cell lines. Primary SCLC and large cell neuroendocrine carcinoma (LCNEC) are typically heterogeneous tumors composed mostly of NE-type cells, but they contain a small number of non-NE-type cells. Importantly, individual cells with NE features exhibit YAP1 loss, whereas the non-NE-type cells exhibit YAP1 expression. Although rare in primary SCLC, some cases of primary LCNEC have many YAP1-positive cells, which is correlated with chemotherapy resistance. YAP1 staining may be useful in the exclusion diagnosis of SCLC or in the selection of treatment for LCNEC.
Efficacy and Safety of Catheter Ablation vs Antiarrhythmic Drugs as Initial Therapy for Management of Symptomatic Paroxysmal Atrial Fibrillation: A Meta-Analysis
Authors: Razzack Aminah Abdul , Lak Hassan Mehmood , Pothuru Suveenkrishna , Rahman Sajedur , Hassan Syed Adeel , Hussain Nabeel , Najeeb Hala , Reddy Krishna Theja , Syeda Humera , Yasmin Farah , Mustafa Ahmad , Chawla Sanchit , Munir Muhammad Bilal , Barakat Amr F , Saliba Walid , Wazni Oussama , Hussein Ayman A.
Published: March 2022

Background: Catheter ablation is an effective treatment for atrial fibrillation (AF), primarily performed in patients who fail antiarrhythmic drugs. Whether early catheter ablation, as first-line therapy, is associated with improved clinical outcomes remains unclear. Methods: Electronic databases (PubMed, Scopus, Embase) were searched until March 28th, 2021. Randomized controlled trials (RCTs) compared catheter ablation vs antiarrhythmic drug therapy as first-line therapy were included. The primary outcome of interest was the first documented recurrence of any atrial tachyarrhythmia (symptomatic or asymptomatic; AF, atrial flutter, and atrial tachycardia). Secondary outcomes included symptomatic atrial tachyarrhythmia (AF, atrial flutter, and atrial tachycardia) and serious adverse events. Unadjusted risk ratios (RR) were calculated from dichotomous data using Mantel Haenszel (M-H) random-effects with statistical significance considered if the confidence interval (CI) excludes one and p < 0.05. Results: A total of six RCTs with 1212 patients (Ablation n = 609; Antiarrhythmic n = 603) were included. Follow- up period ranged from 1–2 years. Patients who underwent ablation were less likely to experience any recurrent atrial tachyarrhythmia when compared to patients receiving antiarrhythmic drugs (RR 0.63; 95% CI 0.55–0.73; p < 0.00001). Symptomatic atrial tachyarrhythmia was also lower in the ablation arm (RR 0.53; 95% CI 0.32–0.87; p = 0.01). No statistically significant differences were noted for overall any type of adverse events (RR 0.93; 95% CI 0.68–1.27; p = 0.64) and cardiovascular adverse events (RR 0.90; 95% CI 0.56–1.44; p = 0.65) respectively. Conclusions: Catheter ablation, as first-line therapy, was associated with a significantly lower rate of tachyarrhythmia recurrence compared to conventional antiarrhythmic drugs, with a similar adverse effect risk profile. These findings support a catheter ablation strategy as first-line therapy among patients with symptomatic paroxysmal atrial fibrillation.
The Feasibility and Long-Term Outcomes of the Crossboss/Stingray for Treating Coronary Chronic Total Occlusions Lesions with Distal Diffuse Disease Landing Zone
Authors: Wang Rutao , Chen Genrui , Mou Fangjun , Liu Yi , Yin Zhiyong , Wang Bo , Gao Haokao , Gao Chao , Tao Ling , Li Chengxiang
Published: March 2022

Background: The feasibility and long-term outcomes of the CrossBoss/Stingray for treating coronary chronic total occlusions (CTO) with distal diffuse disease landing zone remain unclear. Methods: Consecutive CTO patients with distal diffuse lesions that underwent percutaneous coronary intervention by the CrossBoss/Stingray system at Xijing Hospital from April 2016 to October 2020, were included. Patients were analyzed by two groups according to the extent of stenosis in the distal landing zone: 50%–70% stenosis (moderate stenosis group) and >70% stenosis (severe stenosis group). The primary efficacy outcome was technical success, defined as the frequency of true lumen guidewire placement distal to the CTO. The composite endpoint of all-cause death, any stroke, or any revascularization was also explored. Results: A total of 91 consecutive patients were included, with 32 patients in the moderate stenosis group and 59 patients in the severe stenosis group. The mean J-CTO score was 2.5 ± 1.1. The technical success rate was 79.1% (72/91) in the overall population and was similar between the 2 groups: 78.1% (25/32) and 79.7% (47/59) (p = 0.608). No coronary perforation occurred. With a median follow-up of 29 months (IQR: 53–92), the estimated rate of the composite endpoint of all-cause death, any stroke, or any revascularization was 50.4% (all-cause death: 16.6%, any stroke: 1.1%, any revascularization: 36.5%) in the overall population. No significant difference was observed in the rate of the composite endpoint between the moderate stenosis group and the severe stenosis group (45.1% vs. 54.3%, respectively, p = 0.797). Conclusions: In CTO lesions with distal diffuse disease landing zone, the technical success rates of CrossBoss/Stingray and the long-term clinical outcomes were not significantly different between the moderate stenosis group (50%–70%) and the severe stenosis group (>70%). However, the relatively high rate of long-term clinical outcomes, especially any revascularization, warrants further investigations on this indication in future studies.
Resume ekonomi makro
Authors: Nurfadillah
Published: March 2022

Ekonomi islam adalah sebuah sistem ilmu pengetahuan yang menyoroti masalah perekonomian. Sama seperti konsep ekonomi konvensional lainnya . hanya dalam sistem ekonomi ini, nilai-nilai islam menjadi landasan dan dasar dalam setiap aktifitasnya.
Resume ekonomi makro
Authors: saputri Anggraeni Dwi
Published: March 2022

Ruang lingkup Ekonomi islam mencakup dua hal yaitu :Fokus kajian sementara ekonomi islam masih fokus pada pembahasan dibidang keuangan dan perbankanMasih sedikit kajian diluar topik tersebut
Farmed Black Soldier Fly, Hermetia illucens (Diptera: Stratiomyidae), Welfare Considerations: A Model for the Insects as Food and Feed Industry
Authors: Barrett Meghan , Chia Shaphan Yong , Fischer Bob , Tomberlin Jeffery
Published: March 2022

Over two hundred billion black soldier flies (BSF, Hermetia illucens (Diptera: Stratiomyidae)) are reared annually across the globe, with the industry projected to grow substantially in the coming decade. Black soldier flies are being actively explored across the globe for use as livestock feed; fishmeal replacements; biodiesel; human, animal, and food waste management; and even sustainable human protein. Despite the huge number of individual insects reared and interest in BSF welfare by numerous producers and academics, there is no paper that considers the species-specific welfare of BSF in farmed conditions. Based in the five freedoms model of animal welfare, we review factors that relate to BSF welfare in commercial rearing facilities, including: diseases/parasites, abiotic conditions (temperature, humidity/moisture, substrate aeration, light, pupation substrates, and adult spatial needs), adult and larval nutritional considerations, injury and crowding, handling-associated stress, selective breeding and genetic modification, environmental contaminants, and slaughter methods. We conclude with a discussion of the most pressing welfare concerns for the industry, recommendations for altering the conditions that give rise to them, and suggestions for future research directions that would lend valuable insights to BSF welfare. While this summary is BSF-centric, the core topic of animal welfare applies to all insect models currently, or in the future, produced as food and feed.
Coastal River Response to Transgression: A New Look at the Trinity Incised Valley Using Multi-Resolution Seismic Imaging
Authors: Swartz John , Standring Patricia , GOFF JOHN , Gulick Sean , Lowery Christopher
Published: March 2022

Modern lowland river systems show transitions in flow characteristics near coastlines that lead to systematic changes in sediment deposition and stratigraphic architecture. Sensitivity of fluvial morphodynamics to base-level has important implications for the prediction and interpretation of fluvial stratigraphy, particularly in deposits formed during periods of relative sea-level rise such as the early Holocene. Improving our understanding of how fluvial stratigraphy is created and preserved in such environments is crucial to paleoenvironmental reconstruction, sand resource estimation, and mapping subsurface facies distributions. A significant challenge has been capturing the spatiotemporal evolution of such systems on long timescales (centuries to millennia), often due to poor data coverage and resolution. Here we investigate the offshore stratigraphic architecture of the Trinity coastal river system, Texas. The paleo-valley is interpreted to have formed during the last lowstand and filled by backstepping fluvial-deltaic and estuarine sediments over the Holocene. However, the nature of this transition and resulting stratigraphy is unclear. We present unprecedented imaging of the incised valley and fluvial stratigraphy using a combination of over 500km2 of 3D seismic and nearly 700km of full waveform chirp data with 250m line spacing, combined with sediment cores and geotechnical borings. Our chirp processing technique creates images of strata on the decimeter scale, allowing for near outcrop scale mapping and interpretation. Archival industry 3D seismic data show that the basal valley fill is comprised of a highly-amalgamated fluvial channel belt with numerous avulsions and loop cutoffs. The chirp data show the transition of individual fluvial channels from sand rich, laterally migrating systems to muddy channels that depict high rates of vertical aggradation and little lateral movement. We observe the interaction of these channels with the paleo-floodplain and show that aggradation and infilling of the incised valley is dominated by fluvial processes before a transition to bay and estuarine conditions. Our work illustrates that traditional models of incised valley filling and fluvial response to transgression fail to fully capture the morphodynamics of coastal river systems.