bluuebunny/crossref_metadata_2025 huggingface dataset:
Validity and Reliability of the Transcultural Arabic Adaptation of the Food-Mood Questionnaire Among College Students
Authors: Begdache Lina , Radwan Hadia , Abu Qiyas Salma , Abbas Nada , Naja Farah
Published: November 2024

A culturally adapted screening tool for mental health and dietary quality is needed to address the significant challenges in mental health and suboptimal diets among college students. The purpose of this study was to validate the Food-Mood Questionnaire (FMQ), originally developed in English, among Arab college students. Students attending the University of Sharjah were invited to complete the questionnaire (n = 224). Two weeks later, participants completed the same questionnaire again. An exploratory factor analysis revealed three main factors: mental distress, prudent and Western diets. Cronbach’s α was 0.86, 0.72, and 0.531 for the three factors, respectively. The Intra-Class-Correlation (ICC) for the test–retest reliability ranged from 0.67 to 0.87 (p < 0.001). The findings of this study showed that the Arabic version of the FMQ is a valid and reliable tool and could be used to screen for the mental distress and dietary intake of college students in the Arab world.
Select Endocrine Disorders and Exosomes in Early PDAC Diagnosis
Authors: Wlodarczyk Barbara , Durko Lukasz , Walczak Konrad , Talar-Wojnarowska Renata , Malecka-Wojciesko Ewa
Published: November 2024

Disturbances in carbohydrate metabolism are suggested to be the early symptoms of pancreatic ductal adenocarcinoma (PDAC). The accumulated data suggests that endocrine function-related biomarkers may represent a breakthrough in the early detection of PDAC. Factors which may predispose one to the development of PDAC are insulin resistance and hyperinsulinemia. Elevated insulin levels induce the onset of carcinogenesis by altering the differentiation and function of islet cells through stimulating growth factors, including insulin-like growth factors (IGFs). Impaired β cell function, along with the impact of PDAC-released factors (e.g., adrenomedullin (ADM), IGF-1, and macrophage inhibitory factor (MIF) on pancreatic islets, may contribute to the induction of diabetes associated with PDAC. Recently, exosomes have attracted worldwide attention due to their role in varied features of cell function, particularly in cancer progression. Exosomes comprise of small extracellular vesicles produced by almost all cells. These vesicles contain a vast array of biomolecules, including proteins and microRNAs. Exosomes participate in cancer growth and promote angiogenesis. They promote tumorigenesis and metastasis, and are associated with the acquisition of cancer cells resistant to chemotherapy. Data have been accumulating recently on the role of exosomes in the rapid recognition, prognosis and potential therapy of pancreatic cancer.
Arabidopsis GLYI4 Reveals Intriguing Insights into the JA Signaling Pathway and Plant Defense
Authors: Falconieri Gaia Salvatore , Bertini Laura , Fiaschetti Matteo , Bizzarri Elisabetta , Baccelli Ivan , Caruso Carla , Proietti Silvia
Published: November 2024

Plant hormones play a central role in various physiological functions and mediate defense responses against (a)biotic stresses. Jasmonic acid (JA) has emerged as one of the key phytohormones involved in the response to necrotrophic pathogens. Under stressful conditions, plants can also produce small molecules, such as methylglyoxal (MG), a cytotoxic aldehyde. The enzymes glyoxalase I (GLYI) and glyoxalase II primarily detoxify MG. In Arabidopsis thaliana, GLYI4 has been recently characterized as having a crucial role in MG detoxification and emerging involvement in the JA pathway. Here, we investigated the impact of a GLYI4 loss-of-function on the Arabidopsis JA pathway and how MG affects it. The results showed that the glyI4 mutant plant had stunted growth, a smaller rosette diameter, reduced leaf size, and an altered pigment concentration. A gene expression analysis of the JA marker genes showed significant changes in the JA biosynthetic and signaling pathway genes in the glyI4 mutant. Disease resistance bioassays against the necrotroph Botrytis cinerea revealed altered patterns in the glyI4 mutant, likely due to increased oxidative stress. The MG effect has a further negative impact on plant performance. Collectively, these results contribute to clarifying the intricate interconnections between the GLYI4, MG, and JA pathways, opening up new avenues for further explorations of the intricate molecular mechanisms controlling plant stress responses.
The HicAB System: Characteristics and Biological Roles of an Underappreciated Toxin-Antitoxin System
Authors: Encina-Robles Josefa , Pérez-Villalobos Valeria , Bustamante Paula
Published: November 2024

Small genetic elements known as toxin-antitoxin (TA) systems are abundant in bacterial genomes and involved in stress response, phage inhibition, mobile genetic elements maintenance and biofilm formation. Type II TA systems are the most abundant and diverse, and they are organized as bicistronic operons that code for proteins (toxin and antitoxin) able to interact through a nontoxic complex. However, HicAB is one of the type II TA systems that remains understudied. Here, we review the current knowledge of HicAB systems in different bacteria, their main characteristics and the existing evidence to associate them with some biological roles, are described. The accumulative evidence reviewed here, though modest, underscores that HicAB systems are underexplored TA systems with significant potential for future research.
Can Mammalian Reproductive Health Withstand Massive Exposure to Polystyrene Micro- and Nanoplastic Derivatives? A Systematic Review
Authors: Camerano Spelta Rapini Chiara , Di Berardino Chiara , Peserico Alessia , Capacchietti Giulia , Barboni Barbara
Published: November 2024

The widespread use of plastics has increased environmental pollution by micro- and nanoplastics (MNPs), especially polystyrene micro- and nanoplastics (PS-MNPs). These particles are persistent, bioaccumulative, and linked to endocrine-disrupting toxicity, posing risks to reproductive health. This review examines the effects of PS-MNPs on mammalian reproductive systems, focusing on oxidative stress, inflammation, and hormonal imbalances. A comprehensive search in the Web of Science Core Collection, following PRISMA 2020 guidelines, identified studies on the impact of PS-MNPs on mammalian fertility, including oogenesis, spermatogenesis, and folliculogenesis. An analysis of 194 publications revealed significant reproductive harm, such as reduced ovarian size, depleted follicular reserves, increased apoptosis in somatic cells, and disrupted estrous cycles in females, along with impaired sperm quality and hormonal imbalances in males. These effects were linked to endocrine disruption, oxidative stress, and inflammation, leading to cellular and molecular damage. Further research is urgently needed to understand PS-MNPs toxicity mechanisms, develop interventions, and assess long-term reproductive health impacts across generations, highlighting the need to address these challenges given the growing environmental exposure.
Nutraceuticals as Modulators of Molecular Placental Pathways: Their Potential to Prevent and Support the Treatment of Preeclampsia
Authors: Bukowska Patrycja , Bralewska Michalina , Pietrucha Tadeusz , Sakowicz Agata
Published: November 2024

Preeclampsia (PE) is a serious condition characterized by new-onset hypertension and proteinuria or organ dysfunction after the 20th week of gestation, making it a leading cause of maternal and fetal mortality worldwide. Despite extensive research, significant gaps remain in understanding the mechanisms underlying PE, contributing to the ineffectiveness of current prevention and treatment strategies. Consequently, premature cesarean sections often become the primary intervention to safeguard maternal and fetal health. Emerging evidence indicates that placental insufficiency, driven by molecular disturbances, plays a central role in the development of PE. Additionally, the maternal microbiome may be implicated in the pathomechanism of preeclampsia by secreting metabolites that influence maternal inflammation and oxidative stress, thereby affecting placental health. Given the limitations of pharmaceuticals during pregnancy due to potential risks to fetal development and concerns about teratogenic effects, nutraceuticals may provide safer alternatives. Nutraceuticals are food products or dietary supplements that offer health benefits beyond basic nutrition, including plant extracts or probiotics. Their historical use in traditional medicine has provided valuable insights into their safety and efficacy, including for pregnant women. This review will examine how the adoption of nutraceuticals can enhance dysregulated placental pathways, potentially offering benefits in the prevention and treatment of preeclampsia.
A Comparative Evaluation of the Genetic Variant Spectrum in the USH2A Gene in Russian Patients with Isolated and Syndromic Forms of Retinitis Pigmentosa
Authors: Ogorodova Natalya , Stepanova Anna , Kadyshev Vitaly , Kuznetsova Svetlana , Ismagilova Olga , Chukhrova Alena , Polyakov Aleksandr , Kutsev Sergey , Shchagina Olga
Published: November 2024

Pathogenic variants in the USH2A gene are the primary cause of both non-syndromic autosomal recessive inherited retinitis pigmentosa (RP) and the syndromic form, characterized by retinal degeneration and sensorineural hearing loss. This study presents a comparative assessment of the genetic variant spectrum in the USH2A gene among Russian patients in two clinical groups. A retrospective analysis was conducted on massive parallel panel sequencing data from 2415 blood samples of unrelated patients suspected of having hereditary retinal diseases. The copy number of USH2A exons was determined using the quantitative MLPA method with the MRC-Holland SALSA MLPA kit. Biallelic pathogenic and likely pathogenic variants in the USH2A gene were identified in 69 patients (8.7%). In the group of patients with isolated hereditary RP (55 patients), the most frequent pathogenic variants were p.(Glu4445_Ser4449delinsAspLeu) (20.9%), p.(Trp3955*) (15.5%), and p.(Cys934Trp) (5.5%). In patients with the syndromic form (14 patients), the most frequent variants were p.(Trp3955*) (35.7%) and c.8682-9A>G (17.9%). It was found that patients with isolated vision impairment rarely had two “null” variants (17.8%), whereas this was common among patients with both hearing and vision impairment (71.4%) (p ≤ 0.05), explaining the severity of the disease and the earlier onset of clinical symptoms in the syndromic form of RP. Ten previously undescribed loss-of-function variants were identified. The estimated prevalence of USH2A-associated retinal dystrophy in Russia was 1.9 per 100,000 individuals. The obtained data on the differences in the spectra of genetic variants in the USH2A gene in the two studied groups highlight the importance of establishing genotype–phenotype correlations and predicting disease severity, aiming at potential early cochlear implantation and selection of target therapy.
The Multifaceted Ubiquitination of BIK1 During Plant Immunity in Arabidopsis thaliana
Authors: Fu Junhong , Wang Huihui , Chen Yuling , Zhang Chunguang , Zou Yanmin
Published: November 2024

As sessile organisms, the plant immune system plays a vital role in protecting plants from the widespread pathogens in the environment. The Arabidopsis thaliana (Arabidopsis) receptor-like cytoplasmic kinase BOTRYTIS-INDUCED KINASE1 (BIK1) acts as a central regulator during plant immunity. As such, not only the BIK1 protein accumulation but also the attenuation is tightly regulated to ensure effective immune responses. Recent studies have highlighted the critical roles of ubiquitination in maintaining BIK1 homeostasis. Here, we review the latest advances in the ubiquitination of BIK1 in plant immunity, which is mediated by ubiquitin ligases PUB25/26, RHA3A/B, RGLG1/2, and PUB4. Additionally, we summarize and discuss the sites and types of BIK1 ubiquitination. Collectively, these analyses not only illustrate that the differential modifications on BIK1 by multiple ubiquitin ligases hold a crucial position in plant immunity but also provide a good example for future studies on ubiquitin-mediated modifications in plants.
Exploring Plant–Bacterial Symbiosis for Eco-Friendly Agriculture and Enhanced Resilience
Authors: Qadir Muhammad , Iqbal Amjad , Hussain Anwar , Hussain Adil , Shah Farooq , Yun Byung-Wook , Mun Bong-Gyu
Published: November 2024

This review explores the intricate relationship between plants and bacterial endophytes, revealing their multifaceted roles in promoting plant growth, resilience, and defense mechanisms. By selectively shaping their microbiome, plants harness diverse endophytic bacterial strains to enhance nutrient absorption, regulate hormones, mitigate damage, and contribute to overall plant health. The review underscores the potential of bacterial endophytes in self-sustaining agricultural systems, offering solutions to reduce reliance on fertilizers and pesticides. Additionally, the review highlights the importance of endophytes in enhancing plant tolerance to various environmental stresses, such as drought, salinity, extreme temperatures, and heavy metal toxicity. The review emphasizes the significance of understanding and harnessing the mutualistic relationship between plants and endophytes for maximizing agricultural yields and promoting sustainable farming practices.
Marine Geo-Polymer Cement Treated with Seawater, Alkaline Activators, Recycled Particles from Paste, and Recycled Particles from Glass
Authors: Chen Xiaoyang , Wang Yajun , Yang Tao , Bai Yang
Published: November 2024

This study aims to develop the marine geo-polymer cement that was produced with seawater, recycled particles from paste, recycled particles from glass, and alkaline activators, including NaOH or Na2O·3.3SiO2. The physicochemical properties and strength of MGPC were investigated with a Uniaxial Compression Test, Particle Size Analysis, Energy Dispersive Spectrometer, X-ray Diffraction, and Thermal-field Emission Scanning Electron Microscopy. The results indicated that the main hydration products in MGPC were calcium carbonate (CaCO3), silica (SiO2), sodium aluminosilicate hydrate (Na2O·Al2O3·xSiO2·2H2O, N-A-S-H), and aluminum calcium silicate hydrate (CaO·Al2O3·2SiO2·4H2O, C-A-S-H). The calcium carboaluminate (3CaO·Al2O3·CaCO3·32H2O, CO3-AFm) in MGPC was converted into CaCO3 and Friedel’s salt (3CaO·Al2O3·CaCl2·10H2O), which prompted the carbon sequestration. The microstructure of MGPC prepared using Na2O·3.3SiO2 was based on RPG as the matrix, with N-A-S-H, C-A-S-H, and fibrous AFt growing on the periphery. This structure reduces the impact of the alkali–silica reaction on the material and improves its compressive strength. Therefore, the MGPC developed in this study shows the exact benefits of freshwater and natural minerals saving, carbon sequestration, and damage resistance.
Effects of Thermal Demagnetization in Air on the Microstructure and Organic Contamination of NdFeB Magnets
Authors: Grau Laura , Moreno López Rosario , Kubelka Pierre , Burkhardt Fabian , Tomše Tomaž , Kobe Spomenka , Burkhardt Carlo
Published: November 2024

Demagnetization is an essential step for the demounting and safe handling of end-of-life NdFeB. Thermal demagnetization in air is a straightforward option to demount adhesive-fixed or segmented magnets. However, this process is suspected to increase the uptake of contaminants like O, C and Zn from coatings and adhesives, potentially degrading the recyclate quality. This study tests the effects of thermal demagnetization in air at 400 °C for 15 to 240 min on variously coated samples with different initial oxidation levels. Furthermore, the possible reversal of the contaminant uptake is explored. Samples with low previous oxidation levels showed significant uptake in oxygen with a minimal diffusion depth, while the uptake depended on the used coating. The best protectiveness was achieved with NiCuNi with an increase in oxygen of only around 30%. Epoxy (up to ~130% O uptake) and Zn coatings (up to ~80% O uptake) disintegrated during the treatment and offered less protection but still made a difference compared to uncoated samples (up to ~220% O uptake). Samples with high initial oxidation levels show no clear tendency towards further oxygen uptake and the carbon uptake is generally low, likely due to contemporary epoxy coatings featuring a passivation underneath as a barrier layer. Zn infiltration, which carried organic debris, was observed. Short demagnetization times proved to be favorable for limiting the depth of the diffusing contaminants. Mechanical coating removal after thermal demagnetization in air can mitigate the contaminant uptake, producing clean, recyclable end-of-life material.
Si Characterization on Thinning and Singulation Processes for 2.5/3D HBM Package Integration
Authors: Choi MiKyeong , Kim SeaHwan , Noh TaeJoon , Kang DongGil , Jung SeungBoo
Published: November 2024

As stacking technologies, such as 2.5D and 3D packages, continue to accelerate in advanced semiconductor components, the singulation and thinning of Si wafers are becoming increasingly critical. Despite their importance in producing thinner and more reliable Si chips, achieving high reliability remains a challenge, and comprehensive research on the effects of these processing techniques on Si chip integrity is lacking. In this study, the impacts of wafer thinning and singulation on the fracture strength of Si wafers were systematically compared. Three different grinding processes, namely fine grinding, poly-grinding, and polishing, were used for thinning, and the resulting surface morphology and roughness were analyzed using scanning electron microscopy and an interferometer. In addition, the residual mechanical stress on the wafer surface was measured using Raman spectroscopy. The fracture strength of Si wafers and chips was assessed through three-point bending tests. Singulation, including blade dicing, laser dicing, and stealth dicing, was evaluated for its impact on fracture strength. Among these processes, polishing for wafer thinning exhibited the lowest full-width half maximum and intensity ratio of Raman shifts (I480/I520), indicating minimal residual stress and surface defects. Consequently, Si wafers and chips processed through polishing demonstrated the highest fracture strength. Moreover, the 60 µm thick Si wafers and chips showed the highest fracture strength compared with those with thicknesses of 90 and 120 µm, possibly because of the increased flexibility, which mitigates stress. Among the singulation methods, stealth dicing yielded the highest fracture strength, outperforming blade and laser dicing. The combination of wafer thinning via polishing and singulation via stealth dicing presents an optimal solution for producing highly reliable Si chips for 2.5D and 3D packaging. These findings may be valuable in selecting optimal processing technologies for high-reliability Si chip production in industrial settings.
Polyurethanes Made with Blends of Polycarbonates with Different Molecular Weights Showing Adequate Mechanical and Adhesion Properties and Fast Self-Healing at Room Temperature
Authors: Paez-Amieva Yuliet , Mateo-Oliveras Noemí , Martín-Martínez José Miguel
Published: November 2024

Dynamic non-covalent interactions between polycarbonate soft segments have been proposed for explaining the intrinsic self-healing of polyurethanes synthesized with polycarbonate polyols (PUs) at 20 °C. However, these self-healing PUs showed insufficient mechanical properties, and their adhesion properties have not been explored yet. Different PUs with self-healing at 20 °C, acceptable mechanical properties, and high shear strengths (similar to the highest ones reported in the literature) were synthesized by using blends of polycarbonate polyols of molecular weights 1000 and 2000 Da (CD1000 + CD2000). Their structural, thermal, rheological, mechanical, and adhesion (single lap-shear tests) properties were assessed. PUs with higher CD1000 polyol contents exhibited shorter self-healing times and dominant viscous properties due to the higher amount of free carbonate groups, significant carbonate–carbonate interactions, and low micro-phase separation. As the CD2000 polyol content in the PUs increased, slower kinetics and longer self-healing times and higher mechanical and adhesion properties were obtained due to a dominant rheological elastic behavior, soft segments with higher crystallinities, and greater micro-phase separation. All PUs synthesized with CD1000 + CD2000 blends exhibited a mixed phase due to interactions between polycarbonate soft segments of different lengths which favored the self-healing and mobility of the polymer chains, resulting in increased mechanical properties.
Effect of the Sodium Silicate Inhibitor on the Corrosion Protection of AZ31 Magnesium Alloy
Authors: Li Jiawei , Lai Tao , Chen Yang , Yan Hong , Song Honggun , Luo Chao , Hu Zhi
Published: November 2024

The effect of the sodium silicate inhibitor on the corrosion protection of the AZ31 magnesium alloy at room temperature was investigated. The results of electrochemical measurement and weight loss experiments showed that incorporating the sodium silicate significantly enhanced the anti-corrosion property of the AZ31 alloy. When the alloy was immersed in the corrosive solution with the 0.1 M sodium silicate, the corrosion rate of the AZ31 alloy declined to 0.014 mm·y−1, and the inhibition efficiency reached 99.1%. The observation of the corrosion morphology indicated that the magnesium silicate precipitated to cover the corroded area with a thickness of 105 μm, while the silicate ion adsorbed on the uncorroded area. The calculation results of the adsorption energy based on the molecular dynamics indicated that the physical adsorption occurred when the samples were immersed in a sodium silicate solution. Combined with the schematic diagram, the protective mechanism of the adsorption and precipitation after the addition of the sodium silicate inhibitor was investigated.
Advancements in Binary Solvent-Assisted Hydrogel Composites for Wearable Sensing Applications
Authors: Choi Garam , Ali Fathilah , Kim Kyoungho , Kim Minsoo P.
Published: November 2024

The advancement of wearable sensing technologies has been pivotal in revolutionizing healthcare, environmental monitoring, and personal fitness. Among the diverse materials employed in these technologies, multifunctional hydrogel composites have emerged as critical components due to their unique properties, including high water content, flexibility, and biocompatibility. This review provides a comprehensive overview of the state-of-the-art in binary solvent-assisted hydrogel composites for wearable sensing applications. It begins by defining hydrogel composites and their essential attributes for wearable sensors, specifically focusing on binary solvent-assisted methods that enhance their performance and functionality. The review then delves into the applications of these composites in health monitoring, environmental detection, and sports and fitness, highlighting their role in advancing wearable technologies. Despite their promising features, there are significant challenges related to durability, sensitivity, and integration that need to be addressed to fully exploit these materials in wearable devices. This review discusses these challenges and presents potential solutions, including the development of new materials, improvement in fabrication processes, and strategies for achieving multifunctionality and sustainable design. Looking forward, the paper outlines future directions for research in this field, emphasizing the need for innovative materials and technologies that can lead to more effective, reliable, and eco-friendly wearable sensors. This review aims to inspire further research and development in the field of wearable sensing, paving the way for new applications and advancements in healthcare, environmental monitoring, and personal fitness technologies.
Influence of SS316L Nanoparticles on the Sintered Properties of Two-Component Micro-Powder Injection Moulded Bimodal SS316L/Zirconia Bi-Materials
Authors: Basir Al , Sulong Abu Bakar , Muhamad Norhamidi , Juri Afifah Z. , Jamadon Nashrah Hani , Foudzi Farhana Mohd , Radzuan Nabilah Afiqah Mohd , Rashidi Kambiz
Published: November 2024

Two-component micro-powder injection moulding (2C-μPIM) is a prospective approach for fabricating bi-material micro-components of stainless steel 316L (SS316L) and 3 mol% yttria-stabilised zirconia (3YSZ) at an appealing cost. However, the fundamental challenge lies in preventing the formation of large-scale cracks at the interface of two different materials during sintering. This study investigated how SS316L nanoparticles in bimodally configured SS316L powder that incorporated both nanoparticles and microparticles influenced the sintering of 2C-μPIM-processed miniature bi-materials made of bimodal SS316L and 3YSZ. In this study, feedstocks were developed by integrating monomodal (micro-sized) SS316L powder, three types of nano/micro-bimodal SS316L powders, and 3YSZ powder individually with palm stearin and low-density polyethylene binders. The results indicated that increasing the SS316L nanoparticle content to 45 vol.% caused a 19.5% increase in the critical powder loading in the bimodal SS316L powder as compared to that in the monomodal SS316L powder. The addition of SS316L nanoparticles increased the relative density and hardness of the sintered bi-materials, with the maximum values obtained being 96.8% and 1156.8 HV, respectively. Field emission scanning electron microscopy investigations revealed that adding 15 vol.% and 30 vol.% SS316L nanoparticle contents reduced interface cracks in bi-materials significantly, while 45 vol.% resulted in a crack-free interface.
Nanocrystalline Lanthanum Oxide Layers on Tubes Synthesized Using the Metalorganic Chemical Vapor Deposition Technique
Authors: Sawka Agata
Published: November 2024

Lanthanum oxide (La2O3) layers are widely used in electronics, optics, and optoelectronics due to their properties. Lanthanum oxide is also used as a dopant, modifying and improving the properties of other materials in the form of layers, as well as having a large volume. In this work, lanthanum oxide layers were obtained using MOCVD (Metalorganic Chemical Vapor Deposition) on the inner walls of tubular substrates at 600–750 °C. The basic reactant was La(tmhd)3 (tris(2,2,6,6-tetramethyl-3,5-heptanedionato)lanthanum(III)). The evaporation temperature of La(tmhd)3 amounted to 170–200 °C. Pure argon (99.9999%) and air were used as the carrier gases. The air was also intended to remove the carbon from the synthesized layers. Tubes of quartz glass were used as the substrates. La2O3 layers were found to be growing on their inner surfaces. The value of the extended Grx/Rex2 criterion, where Gr—Grashof’s number, Re—Reynolds’ number, x—the distance from the gas inflow point, was below 0.01. The microstructure of the deposited layers of lanthanum oxide was investigated using an electron scanning microscope (SEM). Their chemical composition was analyzed via energy-dispersive X-ray (EDS) analysis. Their phase composition was tested via X-ray diffraction. The transmittance of the layers of lanthanum oxide was determined with the use of UV-Vis spectroscopy. The obtained layers of lanthanum oxide were characterized by a nanocrystalline microstructure and stable cubic structure. They also exhibited good transparency in both ultraviolet (UV) and visible (Vis) light.
Two-Dimensional Pentagonal Materials with Parabolic Dispersion and High Carrier Mobility
Authors: Shao Xiaofei , Liu Xiaobiao , Ma Xikui
Published: November 2024

Materials with high carrier mobility, represented by graphene, have garnered significant interest. However, the zero band gap arising from linear dispersion cannot achieve an ideal on–off ratio in field-effect transistors (FETs), limiting practical applications in certain fields. In contrast, parabolic dispersion usually exhibits extremely high carrier mobility and an appropriate band gap. In this work, we predicted a planar pentagonal lattice composed entirely of pentagons (namely penta-MX2 monolayer), where M = Ni, Pd and Pt, X = group V elements. Using first-principles calculations, we demonstrated a parabolic dispersion within this framework, which results in intriguing phenomena, such as a direct band gap (0.551–1.105 eV) and extraordinary high carrier mobility. For penta-MX2 monolayer, the carrier mobility can attain ~1 × 108 cm2 V−1 s−1 (PBE), surpassing those of black phosphorene, graphene and 2D hexagonal materials. This monolayer also displays anisotropic mechanical properties and significant absorption peaks in the ultraviolet spectrum. Remarkably, 2D penta-MX2 monolayers are promising for successful experimental exfoliation, particularly when X is a nitrogen element, opening up new possibilities for designing two-dimensional semiconductor materials characterized by high carrier mobility.
Investigation of the Thermophysical Simulation and Material Removal Mechanism of the High-Volume-Fraction SiCp/Al Composite in Wire Electrical Discharge Machining
Authors: Chen Zhi , Hu Jiawen , Zhou Hongbing , Wei Yumeng , Zhang Guojun , Han Fenglin
Published: November 2024

SiC particle reinforced aluminum matrix composites (SiCp/Al) are widely used in aviation, weaponry, and automobiles because of their excellent service performance. Wire electrical discharge machining (WEDM) regardless of workpiece hardness has become an alternative method for processing SiCp/Al composites. In this paper, the temperature distribution and the discharge crater size of the SiCp/Al composite are simulated by a thermophysical model during a single-pulse discharge process (SPDP) based on the random distribution of SiC particles. The material removal mechanism of the SiCp/Al composite during the multi-pulse discharge process (MPDP) is revealed, and the surface roughness (Ra) of the SiCp/Al composite is predicted during the MPDP. The thermophysical model simulation results during the MPDP and experimental characterization data indicate that the removal mechanism of SiCp/Al composite material consists of the melting and vaporization of the aluminum matrix, as well as the heat decomposition and shedding of silicon carbide particles. Pulse-on time (Ton), pulse-off time (Toff), and servo voltage (SV) have a great influence on surface roughness. The Ra increases with an increase in Ton and SV, but decreases slightly with an increase in Toff. Moreover, compared with experimental data, the relative error of Ra calculated from the thermophysical model is 0.47–7.54%. This means that the developed thermophysical model has a good application and promotion value for the WEDM of metal matrix composite material.
Enhancement of the Electrical Conductivity and Mechanical Properties of Al-Mg-Si and Al-Mg-Zn Ternary Systems After a T8 Heat Treatment
Authors: Atanacio-Sánchez Xóchitl , Garay-Reyes Carlos Gamaliel , Martínez-García Alfredo , Estrada-Guel Ivanovich , Mendoza-Duarte José Manuel , Guerrero-Seañez Pedro , González-Sánchez Sergio , Rocha-Rangel Enrique , de Jesús Cruz-Rivera José , Gutiérrez-Castañeda Emmanuel José , Martínez-Sánchez Roberto
Published: November 2024

The present research focuses on enhancing the mechanical properties and the electrical conductivity of alloys corresponding to the Al-Mg-Zn (two different compositions) and Al-Mg-Si systems, compared with the commercial 6201-T8 and 1350-H16 alloys, by using a novel approach based on T8 tempering (solution heat treated, cold worked, then artificially aged). After T8 tempering, the Al-Mg-Zn and Al-Mg-Si alloy systems show a better combination of electrical and mechanical properties, with an enhancement of the electrical conductivity by about 2.8% compared to that of 1350 alloy and 13% higher than for the 6201 alloy series. All studied alloys exhibit better mechanical properties than 1350-H16 and are similar to those of 6201-T8.
Mineral Liberation and Concentration Characteristics of Apatite Comminuted by High-Pressure GRU
Authors: Fan Yongbo , Zhang Genghao , Li Shihai , Zhang Li , Guo Jianqiang , Feng Chun
Published: November 2024

Mineral liberation and concentration have always been the core issues in ore processing. The goal of multi-stage crushing and ball milling is liberation because mineral liberation is the foundation of beneficiation. High energy consumption and environmental pollution have always been unavoidable topics. We put forward the method of high-pressure gas rapid unloading (GRU). Particle size followed MR-R distribution. The scanning electron microscopy data showed that the liberation of apatite particles smaller than 4 mm was sufficient by high-pressure GRU methods, and high-grade apatite concentrated in the particle size range of 0.5 to 4 mm. The average grade of the preferred particle size interval was 3%–5% higher than the original ore. Liberation degrees of apatite less than 4 mm are above 88%, which was beneficial for mineral processing. Compared to the traditional crushing method, the GRU method had a higher liberation and concentration in the particle size range of 0.5 to 4 mm. The total energy consumption was about 1.76 kW·h/t, less than that of the traditional crushing method.
Induced Phytomanagement of Multi-Metal Polluted Soil with Conocarpus erectus Supported by Biochar, Lignin, and Citric Acid
Authors: Tauqeer Hafiz Muhammad , Lewińska Karolina , Umar Muhammad , Mahmood Faisal , Shahzad Tanvir , Sagheer Faiqa , Sajid Hina , Chaudhary Iqra , Iqbal Muhammad
Published: November 2024

Induced heavy metals (HMs) phytoextraction from heavily contaminated soils is challenging, as high HM bioavailability causes phytotoxicity and leaching. This study introduces a novel approach for HM immobilization with biochar (BC) and lignin (LN), and later their controlled mobilization with citric acid (CA) in soil. Conocarpus erectus was grown for 120 days in shooting-range soil (SS) polluted with Pb, Cr, Cd, Ni, and Cu. HM concentrations in parts of the plants, their percentage removal, and leaching from SS were measured. Moreover, plant biochemical parameters such as the contents of chlorophyll a (Chl-a), chlorophyll b (Chl-b), protein, ascorbic acid (AsA), amino acids, and total phenolics, along with biophysical parameters such as relative water content (RWC) and water uptake capacity (WUC), were also inspected. Adding BC, LN, and BC+LN to SS improved biomass, as well as the biophysical and biochemical parameters of plants, while efficiently reducing HM concentrations in plant parts, DTPA extract, and leachates compared to the control (CK). However, the greatest amplifications in plant height (82%), dry weight of root (RDW) (109%), and dry weight of shoot (SDW) (87%), plant health, and soil enzymes were noted with the BC+LN+CA treatment, compared with the CK. Moreover, this treatment resulted in Pb, Cr, Cd, Ni, and Cu removal by 68, 30, 69, 59, and 76% from the SS compared to the CK. Surprisingly, each HM concentration in the leachates with BC+LN+CA was below the critical limits for safer water reuse and agricultural purposes. Initial HM immobilization in HM-polluted soils, followed by their secured mobilization during enhanced phytoextraction, can enhance HM removal and reduce their leaching without compromising plant and soil health.
Recovery of Titanium from Red Mud Using Carbothermic Reduction and High Pressure Leaching of the Slag in an Autoclave
Authors: Stopic Srecko , Kostić Duško , Schneider Richard , Sievers Magnus , Wegmann Florian , Emil Kaya Elif , Perušić Mitar , Friedrich Bernd
Published: November 2024

Red mud is a by-product of alumina production, which is largely stored in landfills that can endanger the environment. Red mud, or bauxite residue, is a mixture of inorganic compounds of iron, aluminum, sodium, titanium, calcium and silicon mostly, as well as a large number of rare earth elements in small quantities. Although certain methods of using red mud already exist, none of them have been widely implemented on a large scale. This paper proposes a combination of two methods for the utilization of red mud, first by carbothermic reduction and then, by leaching under high pressure in an autoclave in order to extract useful components from it with a focus on titanium. In the first part of the work, the red mud was reduced with carbon at 1600 °C in an electric arc furnace, with the aim of removing as much iron as possible using magnetic separation. After separation, the slag is leached in an autoclave at different parameters in order to obtain the highest possible yield of titanium, aiming for the formation of titanium oxysulfate and avoiding silica gel formation. A maximal leaching efficiency of titanium of 95% was reached at 150 °C using 5 mol/L sulfuric acid with 9 bar oxygen in 2 h. We found that high-pressure conditions enabled avoiding the formation of silica gel during leaching of the slag using 5 mol/L sulfuric acid, which is a big problem at atmospheric pressure. Previously silica gel formation was prevented using the dry digestion process with 12 mol/L sulfuric acid under atmospheric pressure.
Application of Muscle Synergies for Gait Rehabilitation After Stroke: Implications for Future Research
Authors: Lee Jaehyuk , Kim Kimyung , Cho Youngchae , Kim Hyeongdong
Published: November 2024

Background/Objective: Muscle synergy analysis based on machine learning has significantly advanced our understanding of the mechanisms underlying the central nervous system motor control of gait and has identified abnormal gait synergies in stroke patients through various analytical approaches. However, discrepancies in experimental conditions and computational methods have limited the clinical application of these findings. This review seeks to integrate the results of existing studies on the features of muscle synergies in stroke-related gait abnormalities and provide clinical and research insights into gait rehabilitation. Methods: A systematic search of Web of Science, PubMed, and Scopus was conducted, yielding 10 full-text articles for inclusion. Results: By comprehensively reviewing the consistencies and differences in the study outcomes, we emphasize the need to segment the gait cycle into specific phases (e.g., weight acceptance, push-off, foot clearance, and leg deceleration) during the treatment process of gait rehabilitation and to develop rehabilitation protocols aimed at restoring normal synergy patterns in each gait phase and fractionating reduced synergies. Conclusions: Future research should focus on validating these protocols to improve clinical outcomes and introducing indicators to assess abnormalities in the temporal features of muscle synergies.
Safety and Effectiveness of a 4-Week Diet on Low-Carb Ready-to-Eat Ketogenic Products as Preoperative Care Treatment in Patients Scheduled for Metabolic and Bariatric Surgery
Authors: Santella Biagio , Mingo Monica , Papp Alexander , Rice Mark , Chiappetta Sonja , Calabrese Pietro , Calenda Fabrizia , Pilone Vincenzo , Schiavo Luigi
Published: November 2024

Before metabolic and bariatric surgery (MBS), moderate weight loss and liver left lateral section (LLLS) volume reduction are desirable. Low-carb ketogenic diet-induced weight loss before MBS has been shown to have beneficial effects on the reduction in body weight (BW) and LLLS. However, the nutritional protocol of low-carb ketogenic diet may be hard to keep for prolonged periods due to the lack of sweet taste. Furthermore, transitioning to a low-carb ketogenic diet can cause people to crave foods that are restricted in the ketogenic diet, such as cookies, bread, pasta, and bagels. Therefore, many ready-to-eat low-carb ketogenic products (RLCKP) that mimic carbohydrate-rich foods despite a low-carb composition have been provided to make it easier for the patients to adopt a low-carb lifestyle. To date, there are no studies describing the dietary protocol for efficient and safe use of pre-operative RLCKP in terms of weight and LLLS volume reduction in patients with obesity scheduled for MBS. Therefore, the aim of this study was to assess the safety and effectiveness of a 4-week diet using RLCKP in reducing BW and LLLS volume in patients with obesity scheduled for MBS. Patients with obesity (n = 42) with a mean body mass index (BMI) of 42.4 ± 9.2 kg/m2 scheduled for MBS underwent a 4-week preoperative RLCKP diet intervention. Their weight, LLLS volume, and biochemical and metabolic parameters were measured before and after the diet. Patient compliance was assessed by the presence of ketonuria and weight loss. Qualitative methods (5-point Likert questionnaire) were used to measure diet acceptability and side effects. All patients completed the study. We observed highly significant decreases in BW (−6.5%, p < 0.001), and LLLS volume (−22.3%, p < 0.001) and an amelioration of patient clinical status. All patients showed a high frequency of acceptability and compliance in following the diet. No adverse side effects were reported. Based on our findings, we were able to support the hypothesis that a 4-week preoperative RLCKP diet is safe and effective in reducing BW, and LLLS volume in patients with obesity scheduled for MBS.
Pectin Edible Films Filled with Ilex paraguariensis Concentrate Extract and Its Characterization
Authors: Amadeu Carolina Aparecida Antunes , Silva Francielli Brondani , Souza Clitor Júnior Fernandes , Koschevic Marivane Turim , Schoeninger Vanderleia , Falcão Evaristo Alexandre , Garcia Vitor Augusto Dos Santos , Cardoso Claudia Andrea Lima , Martelli Silvia Maria
Published: November 2024

Ilex paraguariensis (IP) extract was added to prepare edible films using a central rotational composite design (CCRD) 22 with IP extract and sorbitol concentrations as variables. The IP extract was characterized by color parameters, total phenolic content, caffeine, flavonoids, and chlorophyll content, and antioxidant activity and the edible films were assessed for the same analysis and thickness, water vapor permeability (WVP), solubility in water, fluorescence, photodegradation and UV/Vis light barrier, FT-IR, thermogravimetry, and differential exploratory colorimetry. Sorbitol increased thickness and WVP, while the extract influenced the concentration of phenolic compounds in the films. The optimum concentrations of extract and sorbitol were 10% and 15%, respectively. Films presented thermal resistance (until 230 °C) and an excellent barrier to UV light. Furthermore, these films could carry compounds originally in IP, showing good functional properties concerning the water vapor barrier (showing a great variation scale due to the possibility to increase sorbitol or not, between 3.33 and 5.27 g mm/m2 day KPa). The films showed great potential to replace conventional primary packaging, and if consumed with food, as a bullet paper, they can add nutritional value to the packaged product.
State-of-the-Art Review of Microcapsule Self-Repairing Concrete: Principles, Applications, Test Methods, Prospects
Authors: Jiang Lu , Wu Mingli , Du Fei , Chen Dongdong , Xiao Lihua , Chen Wei , Du Wei , Ding Qingjun
Published: November 2024

Cement-based materials are widely used in construction worldwide, but they are vulnerable to environmental stressors and thermal fluctuations, leading to the formation of internal cracks that compromise structural integrity and durability. Traditional repair methods such as surface coatings, grouting, and groove filling are often costly and labor-intensive. In response, self-repairing technologies for cement-based materials have emerged as an innovative and promising solution, offering the potential to significantly extend the lifespan of structures and reduce maintenance costs. A particularly novel approach is the development of microcapsule-based self-repairing concrete. In this system, repair agents are encapsulated within microcapsules and combined with curing agents in the concrete matrix. When cracks form, the microcapsules rupture, releasing the repair agents to autonomously heal the damage. This self-repairing mechanism is characterized by its high efficiency, durability, environmental sustainability, and versatility, making it a promising alternative to traditional repair methods. Recent research has focused on the development of microcapsules with various core materials, such as TDI (toluene diisocyanate), IPDI (isophorone diisocyanate), or epoxy resin, as well as composite shell materials including paraffin wax, PE (polyethylene) wax, nano-SiO2, and nano-CaCO3. A novel advancement in this area involves the enhancement of microcapsules through the incorporation of magnetic nanomaterials into the shell, providing new possibilities for self-repairing systems that address cracks in cement-based materials.
A Reparameterization Feature Redundancy Extract Network for Unmanned Aerial Vehicles Detection
Authors: Zhang Shijie , Yang Xu , Geng Chao , Li Xinyang
Published: November 2024

In unmanned aerial vehicles (UAVs) detection, challenges such as occlusion, complex backgrounds, motion blur, and inference time often lead to false detections and missed detections. General object detection frameworks encounter difficulties in adequately tackling these challenges, leading to substantial information loss during network downsampling, inadequate feature fusion, and being unable to meet real-time requirements. In this paper, we propose a Real-Time Small Object Detection YOLO (RTSOD-YOLO) model to tackle the various challenges faced in UAVs detection. We further enhance the adaptive nature of the Adown module by incorporating an adaptive spatial attention mechanism. This mechanism processes the downsampled feature maps, enabling the model to better focus on key regions. Secondly, to address the issue of insufficient feature fusion, we employ combined serial and parallel triple feature encoding (TFE). This approach fuses scale-sequence features from both shallow features and twice-encoded features, resulting in a new small-scale object detection layer. While enhancing the global context awareness of the existing detection layers, this also enriches the small-scale object detection layer with detailed information. Since rich redundant features often ensure a comprehensive understanding of the input, which is a key characteristic of deep neural networks, we propose a more efficient redundant feature generation module. This module generates more feature maps with fewer parameters. Additionally, we introduce reparameterization techniques to compensate for potential feature loss while further improving the model’s inference speed. Experimental results demonstrate that our proposed RTSOD-YOLO achieves superior detection performance, with mAP50/mAP50:95 reaching 97.3%/51.7%, which represents improvement of 3%/3.5% over YOLOv8, and 2.6%/0.1% higher than YOLOv10. Additionally, it has the lowest parameter count and FLOPs, making it highly efficient in terms of computational resources.