bluuebunny/crossref_metadata_2025 huggingface dataset:
Memory modulation: Dominance of negative visual context over neutral verbal memory
Authors: Kozak Stas , Herz Noa , Tocker Maya , Bar-Haim Yair , Censor Nitzan
Published: October 2024

Neutral memories can be modulated via intentional memory control paradigms such as directed forgetting. In addition, previous studies have shown that neutral visual memories can be modulated indirectly, via remember and forget instructions towards competing verbal memories. Here we show that direct modulation of neutral verbal memory strength is impaired by negative visual context, and that negative visual context is resistant to indirect memory modulation. Participants were directly instructed to intentionally remember or forget newly encoded neutral verbal information. Importantly, this verbal information was interleaved with embedded negative visual context. Results showed that negative visual context eliminated the well-documented effect of direct instructions to intentionally remember verbal content. Furthermore, negative visual memory was highly persistent, overcoming its sensitivity to indirect modulation shown in previous studies. Finally, these memory effects persisted to the following day. These results demonstrate the dominance of negative visual context over neutral content, highlighting the challenges associated with memory modulation in psychopathologies involving maladaptive processing of negative visual memories.
Periodontitis and pre-eclampsia among pregnant women in Rwanda: A case-control study
Authors: Gatarayiha Agnes , Ntaganira Joseph , Brookes Zoe , Mutesa Léon , Gustafsson Anders , Rulisa Stephen
Published: October 2024

Introduction

Several studies have indicated that the presence of periodontitis during pregnancy could increase the risk of developing pre-eclampsia, thereby negatively influencing pregnancy outcomes for both the mother and child. Notably, despite the high prevalence of both periodontitis and adverse pregnancy outcomes in Rwanda, there exists a crucial evidence gap concerning the precise relationship between periodontitis and pre-eclampsia.

Objectives

The aim of this study was to assess the association between periodontitis and pre-eclampsia amongst pregnant women in Rwanda.

Methods and materials

Employing an unmatched 1:2 case-control design, we studied 52 pre-eclamptic and 104 non-pre-eclamptic pregnant women aged ≥18 years at two referral hospitals in Rwanda. Pre-eclampsia was defined as a systolic blood pressure ≥ 140 and diastolic blood pressure ≥ 90 mm Hg, diagnosed after 20 weeks of gestation and proteinuria of ≥300mL in 24 hours of urine collection. Periodontitis was defined as the presence of two or more teeth with one or more sites with a pocket depth ≥ 4mm and clinical attachment loss >3 mm at the same site, assessed through clinical attachment loss measurement. Bivariate analysis and logistic regression were used to estimate Odds ratio (ORs) and 95% confidence interval.

Results

The prevalence of periodontitis was significantly higher among women with pre-eclampsia, compared to pregnant women without pre-eclampsia, at 90.4% and 55.8%, respectively (p< 0.001). Pregnant Women with periodontitis were 3.85 times more likely to develop pre-eclampsia after controlling for relevant confounders (adjusted Odds Ratio [aOR] = 3.85, 95%CI = 1.14–12.97, p<0.05).

Conclusion

This study results indicates that periodontitis is significantly associated with pre-eclampsia among pregnant women in Rwanda. These findings suggest that future research should explore whether enhancing periodontal health during pregnancy could contribute to reducing pre-eclampsia in this specific population.
Isotretinoin promotes elimination of translation-competent HIV latent reservoirs in CD4T cells
Authors: Howard J. Natalie , Levinger Callie , Deletsu Selase , Fromentin Rémi , Chomont Nicolas , Bosque Alberto ,   for the AIDS Clinical Trials Group (ACTG) A5325 Team
Published: October 2024

Development of novel therapeutic strategies that reactivate latent HIV and sensitize reactivated cells to apoptosis is crucial towards elimination of the latent viral reservoir. Among the clinically relevant latency reversing agents (LRA) under investigation, the γc-cytokine IL-15 and the superagonist N-803 have been shown to reactivate latent HIV ex vivo and in vivo. However, their clinical benefit can be hindered by IL-15 promoting survival of infected cells. We previously identified a small molecule, HODHBt, that sensitizes latently infected cells to death upon reactivation with γc-cytokines through a STAT-dependent pathway. In here, we aimed to identify and evaluate FDA-approved compounds that could also sensitize HIV-infected cells to apoptosis. Using the Connectivity Map (CMap), we identified the retinol derivative 13-cis-retinoic acid (Isotretinoin) causes similar transcriptional changes as HODHBt. Isotretinoin enhances IL-15-mediated latency reversal without inducing proliferation of memory CD4 T cells. Ex vivo analysis of PBMCs from ACTG A5325, where Isotretinoin was administered to ART-suppressed people with HIV, showed that Isotretinoin treatment enhances IL-15-mediated latency reversal. Furthermore, we showed that a combination of IL-15 with Isotretinoin promotes the reduction of translation-competent reservoirs ex vivo. Mechanistically, combination of IL-15 and Isotretinoin increases caspase-3 activation specifically in HIV-infected cells but not uninfected cells. Our results suggest that Isotretinoin can be a novel approach to target and eliminate translation-competent HIV reservoirs.
ReShaping Worlds: Thinking with and through positionality for thriving futures
Authors: Nguyen Thao , Leong Jacina , Sharp Kristen
Published: October 2024

Art theory as taught in Australian higher education still predominantly focuses on Eurocentric artistic practices, methodologies and histories, with practices by First Nations artists and artists of colour often relegated to tokenistic one-off lectures. This approach to syllabus fails to reflect the depth and breadth of contemporary art and creates an inherently imbalanced perspective disconnected from the diverse experiences of students. Simultaneously, students are expressing their own expectations for an empowered and critically reflexive art education. Using the undergraduate art theory course, ReShaping Worlds, as a case study, this collaborative article discusses the importance of developing curriculum that provides students with an expanded perspective on artistic and curatorial practices by decentring hegemonic Eurocentric art narratives and reflecting on positionality. In doing so, we also highlight our roles as arts educators in facilitating and supporting reflexive and critical practice amid climates of political, social and ecological uncertainty.
Boundary obsessions
Authors: Ugazio Renée , Humphries Clare
Published: October 2024

Boundaries in contemporary art practice and education contexts are often conceived as distinctions between disciplines, inscribed through material conventions and discursive traditions. In art, a field that continually touts trans-disciplinarity and post-medium approaches, it is considered productive to occupy multiple disciplinary positions and effectively enlarge or re-draw the territory of possible creative action. This obsession with disciplinary limits reveals a language of spatial metaphors (fields, frontiers and domains) and breaching actions (breaking boundaries, expansion). In this article we highlight how the language of disciplinarity today is spatialized, and premised on notions of imperialist territoriality which are at odds with efforts to decolonize art. We speculate on other ways to approach disciplinarity without theorizing boundaries and their rupture, and re-consider discipline through: ecologies of teaching and learning, an imaginative burrowing under the surface, and working with discipline as an agential material.
Proceso de elaboración de un cuestionario de autoinforme sobre problemas clínicos coocurrentes al autismo sin discapacidad intelectual asociada
Authors: Danés Henríquez Marta , Belinchón Carmona Mercedes , Sotillo Méndez María
Published: October 2024

La alta prevalencia de problemas clínicos de salud mental que presentan las personas diagnosticadas de Trastorno del Espectro del Autismo sin Discapacidad Intelectual asociada (TEA-noDI) evidencia la necesidad de dotar, a estas personas y a los profesionales que trabajan en este ámbito, de instrumentos de detección fáciles de administrar. La elaboración de instrumentos así exige cautelas específicas dadas las características cognitivas y lingüísticas de estas personas. En este artículo se detallan las primeras fases de elaboración de un cuestionario de autoinforme para detectar posibles problemas clínicos asociados para ejemplificar un posible método a seguir en estos casos. Se espera así facilitar que otros investigadores y profesionales puedan desarrollar instrumentos de este tipo que, con bajo coste, faciliten la atención profesional a unos problemas que, como expresa el propio colectivo de personas diagnosticadas de TEA-noDI, pueden limitar su calidad de vida más que el TEA en sí.
Development and Validation of a Pediatric Celiac Disease-Specific Quality of Life Measure
Authors: Coburn Shayna , Trojanowski Paige J. , Vagadori Jack , Hinds Pamela , Germone Monique , Liu Edwin , Streisand Randi , Bost James
Published: October 2024

INTRODUCTION:

Quality of life (QOL) is critical in screening and management of chronic medical conditions, including celiac disease (CD). The aim of this project was to develop a CD-specific pediatric QOL measure (Celiac Disease Life Inventory of Family Experiences [CDLIFE]) with parallel self-report and parent-report forms by generating items through concept elicitation interviews, iterative refinement using cognitive debriefing interviews, and evaluating its psychometric properties and validity.

METHODS:

Concept elicitation interviews were conducted to develop items (9 youth ages 8–19 years with CD; 10 parents of youth with CD), followed by cognitive interviews with additional stakeholders (3 youth with CD, 3 parents, and 8 clinicians) and item administration (parent/youth reports: n = 103/102). Analyses included response frequencies, internal consistency reliability, exploratory factor analyses, and correlations with related measures (Patient-Reported Outcomes Measurement Information System, Pediatric Quality of Life Inventory, and Gluten-Free Diet-Visual Analog Scale).

RESULTS:

From concept elicitation interviews, 42 youth and 45 parent items were developed. Cognitive debriefing interviews yielded 36 refined items. Psychometric analyses identified 15 items to remove due to ceiling/floor effects, poor item-to-test correlations, and youth-parent mismatch or conceptual mismatch. Total score internal consistency was high (αs = 0.89–0.90). A 4-factor model solution had the best fit (Social Impact, External Support, Adaptive Vigilance, Eating Behaviors/Adjustment) with a fifth single-item domain (Financial Resources). The final CDLIFE (21 items) total scores correlated with most related measures in expected directions for parent and youth forms.

DISCUSSION:

The CDLIFE may facilitate insight into CD-specific QOL for youth ages 2–18 years, capturing important dimensions of physical and socioemotional health. Administering the CDLIFE will help identify and track families needing support.
Ospravedlnění subverze: Proč Nussbaumová neporozuměla (lepší interpretaci) Butlerové
Authors: Herstein Ori J.
Published: October 2024

Czech translation of O. J. Herstein’s Justifying Subversion: Why Nussbaum Got (the Better Interpretation of) Butler Wrong.
Latvian Research Libraries from the 1980s to the Present
Authors: Vilks Andris , Dreimane Jana
Published: October 2024

This article explores the evolution of Latvia’s leading research libraries from the final decade of Soviet occupation to the present day. After the Soviet time, libraries have undergone great changes and have become modern, multifunctional cultural, educational, and research centres responding to the needs and expectations of society. The article focuses on the National Library of Latvia, centre of the Latvian library system since its foundation in 1919. The State Unified Library Information System has modernised the entire network of publicly accessible libraries. Twelve major libraries have been involved in developing the electronic catalogue. Work on the Latvian National Digital Library has been ongoing since 2006. The Latvian Government’s decision in 2002 to build a new National Library (opened in 2014) has also spurred on the renovation or construction of many other libraries in Latvia.
Clostebol and sport: about controversies involving contamination vs. doping offence
Authors: Kintz Pascal , Gheddar Laurie , Pichini Simona , Plebani Mario , Salomone Alberto
Published: October 2024

Clostebol, the 4-chloro derivative of testosterone, available as Over The Counter product in pharmacies and drugstores in several countries, is mostly commercialized as a cream or spray in the form of acetate ester. As other anabolic steroids, clostebol is listed as a prohibited substance by the World Anti-Doping Agency (WADA). Controlled transdermal application of clostebol acetate has been reported to produce detectable amounts of its metabolites in urine, even after a single exposure. Indeed, a low urine concentration can be interpreted as the tail of a drug voluntarily used to enhance performance or a direct consequence of a contamination. The increased number of adverse analytical findings (AAFs) involving clostebol reported in the last years should lead to highlight the need for athletes to be warned against personal and /or accidental use/exposure of dermal preparation containing this doping agent. Further discussion on possible threshold limits and laboratory testing on different matrices (e.g. hair) to better clarify the origin of minimal amounts of clostebol in urines is advisable.
Monosodium glutamate induces hypothalamic–pituitary–adrenal axis hyperactivation, glucocorticoid receptors down-regulation, and systemic inflammatory response in young male rats: Impact on miR-155 and miR-218
Authors: Atteia Hebatallah Husseini , Gharib Amal F. , Asker Mervat El-Sayed , Arafa Manar Hamed , Sakr Amr Tawfik
Published: October 2024

Young children are attracted to flavored foods with enhancers, particularly monosodium glutamate (MSG). Experimental studies have proven that MSG can alter the hypothalamic–pituitary–adrenal (HPA) axis response in neonates. We, therefore, investigated the modulation of microRNAs (miRNAs) by dietary MSG and its association with the stimulation of the HPA axis and inflammatory response in young male rats. One-month-old male rats were fed chow enriched with MSG (3 g/kg) for 16 weeks. Feeding MSG to rats markedly up-regulated hypothalamic miR-218, Toll-like receptors-4, and nuclear factor-kB but down-regulated miR-155 and glucocorticoid receptors (GR). In addition, it triggered a remarkable elevation in adrenocortical lipid peroxidation and depletion of antioxidants. These changes were coupled with increased plasma levels of the HPA axis hormones, comprising corticotropin-releasing hormone, adrenocorticotropic hormone, corticosterone levels, and serum pro-inflammatory cytokines. Taken together, current findings indicated that MSG caused an activation of the HPA axis, a down-regulation of GRs, and a systemic inflammatory response. These disturbances were associated with modulating hypothalamic miRNAs, encompassing miR-218 and 155.
Hardfacing of GX40CrNiSi25-20 cast stainless steel with an austenitic manganese steel electrode
Authors: Mitelea Ion , Cosma Daniela , Karancsi Olimpiu , Burcă Mircea , Crăciunescu Corneliu Marius , Uțu Ion-Dragoş
Published: October 2024

To enhance the wear and corrosion resistance of engineering components, various surface modification techniques have been devised. Among these, arc welding processes employing specialized electrodes offer relatively straightforward methods with low production costs for hardfacing applications. This paper focuses on the hardfacing process using pulsed current arc welding to reinforce cast austenitic steel structural components, aiming to prolong their lifespan. Typically, hardfacing coatings utilize Fe, Ni, and Co-based alloys. Among these, Fe-based alloys, such as manganese austenitic alloys employed in our experiments, are favored for their robust mechanical work hardening capacity, resulting in significant hardness enhancements (from 186–219 HV5 in the as-deposited layer to 468–492 HV5 after mechanical work hardening) under intense wear and impact conditions. The innovation of the hardfacing process developed in this study lies in utilizing a universal TIG source adapted for manual welding with a covered electrode in pulsed current mode. This hardfacing technique can be applied to both worn components in operation and new ones before being put into service, thereby ensuring long-term durability and reducing maintenance costs.
THE ISSUE OF THE UK’S PAKISTANI COMMUNITY ACCULTURATION
Authors:   Patrice Lumumba Peoples’ Friendship University of Russia, Klimenko Ulyana
Published: October 2024

The article is dedicated to the analysis of a number of features inherent in the UK’s Pakistani community, which manifest in the social and cultural life of the country, based on the research conducted by British sociologists in the time span from 2010 to 2024. The article examines the approaches British Pakistani people take in respect to their identity, emphasizes the importance of personal contacts and the creation of their own self in spaces which are used to exchange experience and which are not directly related to the home and business environment. The emphasis is placed on the complexity and mosaicism of the UK’s Pakistani diaspora members’ identity, as well as on the importance of using art as an instrument of intercultural dialogue. There is a prospect of even greater divergence of British Pakistanis’ points of view in the future, however, the general trend of their acculturation is positive, and at the moment their activity both in the media (television, radio) and in everyday life has slightly increased compared to previous decades.
EU – UKRAINE NEGOTIATIONS: UNDERWATER STONES
Authors:   Institute of Europe, Russian Academy of Sciences, Mironenko Viktor
Published: October 2024

The article discusses the circumstances of the decision to start negotiations between the EU and Ukraine on membership in the union, the prospects and difficulties of the new and, as it is commonly believed, the final stage of Ukraine’s accession to this interstate union. The proposed and adopted framework of negotiations does not provide a clear answer to the main question of interest to Ukraine about the timing of accession and the EU’s readiness for it. The author believes that despite the fact that accession for the first time in an official EU document is named as the ultimate goal of the relevant policy, the proposed path to it does not differ much from those offered to the candidate countries earlier. The EU statement and the negotiating framework do not adequately reflect the size and importance of the country in question, as well as the changed context in which the negotiations are to be conducted. Although the main focus of the parties is on the legal aspects of the problem, the pace and, most importantly, the outcome of the negotiations will largely depend on economic and political circumstances. In the author’s opinion, this implies a rethinking and adjustment of the EU enlargement processes in general and Ukraine’s accession in particular.
Race-ing Masculinity
Authors: Calderón-Sandoval Orianna , Rivera-Izquierdo Ángela , Sánchez-Espinosa Adelina
Published: October 2024

Studies about representations of Latinidad in US and European media have identified stereotypes like criminalization and hypersexualization. Furthermore, it has been argued that comedy operates as a double-edged sword in exposing racism, as humor can be deployed to simultaneously mask/justify and show/denounce racial discrimination and monolithic representations of Latinidad. Using a feminist intersectional perspective that foregrounds constructions of masculinities and racialization/migration as exclusionary factors, this essay discusses how RTVE Playz, the digital platform of the Spanish public television aimed at young audiences, represents Latinidad in its series Riders (2021). Situated within the dynamics of racialization in Spain, Riders stands out as an example of dark humor that both complicates and reinforces stereotypes. Through a close reading of the series, we assess its response to current social, political and cultural citizenship challenges.
Documentary as Memory Archive and Feminist Practice
Authors: Llanos M. Bernardita
Published: October 2024

This essay reflects on the significance of documentary filmmaking in the context of Latin American documentaries, in general, and Chilean films, in particular. It also reflects on how Latinas’ diasporic memories of place affect identity and how we think of the past through language and images. Feminist film activism is a way to build an archive of women’s lives and voices revealing how gender shapes them. The short documentary La chispa en la pradera (Spark in the Meadow, 2023) displays feminist activism and feminist memories that cut across different generations of women fighting for equality and justice in contemporary Chile.
Jayaera
Authors: Rivera-Velázquez Celiany
Published: October 2024

The article reflects on the evolution of the Afro-Caribbean neologism “jayaera”—a deeply internal feeling of joy when one can freely be oneself, coined by performer Macha Colón. By conducting a close reading of how, since 2008, Macha popularized “Jayá” (adj.), and by studying D’Chamacas party as a catalyst for “jayaera” (n.), this article analyzes the collectivization of “cuir bliss” and examines its multimedia origins. It also explores how, in 2019, there was a marked shift toward “combative jayaera” (n. with adj. modifier) that escalates “cuir bliss” into “cuir irreverence” through #8M Slut Walks, the Perreo Combativo during #RickyRenuncia protests, and development of the Caribbean kiki scene. The article argues that “jayaera” has gradually separated from its creator through reinterpretations and adaptations, notably through performer Ana Macho’s song “Jayau,” alternative Pride celebrations, and as a strategy for political parties to present themselves as open to LGBTQIA+ issues. Lastly, the article revisits Macha's latest exploration of this Afro-Caribbean multimedia neologism through the Templo de la Jayaera (est. 2021), where participants identify and develop spaces for contemplative experiences, further engaging with the slippery and transient nature of decolonial joy and cuir bliss for Puerto Ricans.
“I Am a Meme”
Authors: Blanco Martínez Miguel Ángel , Yola Gad
Published: October 2024

Founder of the collectives Casa Drag Latina and House of Gad, Gad Yola is an Afro-Peruvian multidisciplinary artivist based in the city of Madrid. As part of a trans-Atlantic Latinx queer media history, Gad Yola’s career allows us to inquire about what can be described as transvestite, antiracist, and transfeminist drag “positioning” against injustices happening on both sides of the Atlantic. Be this their rejection of state violence in Peru, their support for the massive regularization of migrants in Spain, their critique of the racist gaze, or their celebration of brown bodies, Gad Yola’s interventions significantly contribute to the cultural articulation of antiracism in Spain. The following interview will consider the digital and feminist interrelation by focusing on Gad Yola’s identification with antiracism, transfeminism, and their references, as well as on the use of social networks as identity and community resources.
Radios y Cacerolas
Authors: González Luisa
Published: October 2024

This article elaborates a feminist digital activist perspective on the Colombian national strike of 2021 through the work of two women-led collectives (colectivas) in which I participated from afar, as part of the Colombian diaspora. Radio Lila is a collective of women living in Cali’s oriente, and Cacerola Collective is formed by Colombians in the diaspora, mostly people working in the creative industries. Through the study of these colectivas’s praxis, this article argues that women-led collectives use digital tools and the internet not only to set up political actions but also to create online places for care and mourning. This argument makes conspicuous how there is a gap in the research on digital activism, concerning the emotional tools activists seek to transit political uprisals and their aftermaths. In other words, we see here how feminist research on social media can also focus on retreating, going offline, as a way of personal and communal care.
A cluster approach to matching the competences of data specialists with skills in demand on the labour market
Authors: Kobets Vitaliy M. , Gulin Oleksii V. , Nosov Pavlo S.
Published: October 2024

This paper addresses the challenge of aligning the competences of data specialists with skills in demand on the labour market in the rapidly evolving field of data science. Using an open dataset of 3,744 IT job postings, the study applies K-means clustering to identify key skill groupings for data specialist positions. The optimal number of clusters is determined using the elbow method, resulting in four distinct clusters: Data Analyst & Engineer, Data Platform Engineer, Data Science & Engineering Specialist, and Cloud Data Engineer. The research methodology employs unsupervised learning techniques, specifically K-means clustering, to analyze the distribution of skills across job postings. The clusters are visualized using t-distributed Stochastic Neighbor Embedding (t-SNE), providing insights into the relationships between different skill sets. The study reveals that job titles do not always unambiguously define the required skills, emphasizing the importance of focusing on specific skill sets rather than job titles alone. To bridge the gap between specific subject competences academic programs and industry requirements, the paper proposes a novel approach for comparing the proportion of skills in job clusters with the proportion of professional competencies in academic programs. This method is demonstrated using the Information Systems and Technologies Master's program at Kherson State University as a case study. The chi-square test is applied to confirm the statistical similarity between the skill structure of the Data Science & Engineering Specialist cluster and the competency structure of the academic program. The findings highlight the importance of continuous adaptation of profile of academic program to meet evolving industry needs. The proposed approach provides a data-driven framework for universities to align their programs with labor market demands, potentially improving graduate employability in the data science field. The study also underscores the need for personalized learning paths that can be tailored to individual career goals and skill gaps. Future research directions include the development of an artificial intelligence system to form individualized educational trajectories based on the skills required for specific job clusters. This could further enhance the alignment between education and industry needs, preparing students more effectively for the dynamic data science job market.
An expert system of recommendations for combating cyber threats using CVSS metrics and game theory
Authors: Mishchenko Maksym V. , Dorosh Mariia S.
Published: October 2024

This study is focused on the creation of an expert system for generating recommendations on cyber security. The developed expert system uses a game-theoretic model as a inference engine to transform expert knowledge into recommendations for end-users, who may be chief IT security officers (CISOs), system administrators, or cyber security engineers. Expert knowledge is presented in the form of an estimate of the base group of CVSS metrics - Common Vulnerability Score System, for each type of attack and adjusted values of CVSS in the case that the counterattack strategy is applied. Given a set of attacks and a base of expert attack knowledge, the system generates a game matrix of zero-sum game with a cybercriminal and a cyberdefense expert as players. The inference engine of the expert system is a game-theoretic model responsible for solving the game using the Brown-Robinson iterative method and generating cyber protection recommendations. An experiment was conducted on the convergence of the BrownRobinson algorithm on the 2022 vulnerability dataset from the Cybersecurity and Infrastructure Security Agency database, as a result of which it was determined that the convergence of the algorithm for solving the matrix game is achieved at a number of iterations of 1000. As a result of the work, expert system was designed and implemented along with the Web interface, which provides input by experts of CVSS level assessments of collected threats, threats countermeasures and output of recommendations for combating cyber threats
Quality control of functioning of the structure “object-thermoelectric cooler-heat sink” of the system of providing thermal modes
Authors: Zaykov Vladimir P. , Mescheryakov Vladimir I. , Ustenko Andriy S. , Troynina Anastasiya S.
Published: October 2024

The analysis of the mathematical model of the system of providing thermal modes with the use of thermoelectric cooling to assess the influence of the conditions of heat exchange of the heat sink with the medium on the main parameters, reliability indicators and dynamic characteristics of a single-cascade thermoelectric cooler at a given temperature level of cooling, medium temperature, geometry of branches of thermoelements for different current operating modes is considered. The results of calculations of the main significant parameters, reliability indicators, dynamic and energy characteristics of a single-cascade cooler and heat sink of the selected design at a given temperature level of cooling, medium temperature, thermal load, geometry of branches of thermoelements for various characteristic current operating modes are given, when the conditions of heat exchange on the heat sink of the given design under variation of the heat transfer coefficient. It is shown that with the increase of air flow velocity on the heat sink the heat transfer coefficient increases and thus the temperature drop on the heat sink of the thermoelectric cooler with the medium decreases, which allows to significantly reduce the relative failure rate of the cooler and thus increase the probability of failure-free operation of the whole device. When operating a system for providing thermal modes comprising a cooling device, a heat sink, and an electric fan used for dissipating heat output to the environment, different modes of operation of the electric fan (air flow rate) can be used. With the increase in air flow rate of the electric fan increases the velocity of air flow in the live section of the heat sink of a given design, which leads to an increase in the heat transfer coefficient. This, in turn, makes it possible to reduce the temperature drop at a given design of the system for ensuring thermal modes. The possibility of control of reliability indicators, namely, relative intensity of failures and probability of failure-free operation of thermal mode systems of different designs (current modes, number of thermocouples, surface area of the heat sink) at a given cooling level (medium temperature, thermal load, geometry of thermocouples) under changing conditions of heat exchange of the heat sink with the medium is considered.
Development of a software service for stock price forecasting based on sentiment analysis and autoregressive models
Authors: Kobets Vitaliy M. , Stang Nikita D.
Published: October 2024

This paper addresses the critical need for efficient market analysis tools in the era of big data and artificial intelligence. We present a novel software service that integrates real-time news sentiment analysis with stock market prediction, enhancing the accuracy and speed of trading decisions. The system employs APIs for data collection, FinBERT for sentiment analysis, and MongoDB for data storage, overcoming limitations of existing platforms like Investing.com and MarketWatch. Our methodology combines sentiment analysis with autoregressive models to forecast stock prices for 11 major companies. The experiment utilized 141 observations, applying multiple regression and binary outcome models. Results demonstrate that investor sentiment significantly affects stock prices for 2 out of 11 companies, with Meta showing a 70 % determination coefficient in price direction changes based on sentiment. The study reveals that incorporating both quantitative (previous stock prices) and qualitative (sentiment) data improves forecast accuracy for certain stocks. This research contributes to the field of financial analytics by providing a more comprehensive approach to stock price prediction, integrating ML models and data analytics to support informed decision-making in dynamic financial markets.
Effects of iodine contrast media on thyroid function – a prospective study
Authors: Carlqvist Jeanette , Nyman Ulf , Brandberg John , Nyström Helena Filipsson , Hellström Mikael
Published: October 2024

Objectives

When exposed to iodine contrast medium (ICM), thyroid dysfunction may develop, due to excess amounts of iodide. The incidence of contrast-induced thyroid dysfunction has been difficult to interpret, because of the observational and retrospective designs of most previous studies. With the Swedish CArdioPulmonary bioImage Study (SCAPIS), where randomly selected individuals aged 50–65 years, underwent contrast-enhanced coronary CT angiography (CCTA), we were able to prospectively assess the incidence, magnitude and clinical impact of contrast-induced thyroid dysfunction.

Methods

In 422 individuals, thyroid hormone levels were analysed before and 4–12 weeks after CCTA. Thyroid-related patient-reported outcome questionnaires (ThyPRO) at the time of pre and post-CCTA blood samplings were provided by 368 of those individuals. Thyroid peroxidase antibodies (TPOab) were analysed and an ultrasound of the thyroid gland was performed to detect any thyroid nodules.

Results

There was a small statistically significant effect on thyroid hormone levels but no cases of overt hypo- or hyperthyroidism after ICM. Subclinical hypo- or hyperthyroidism or isolated low/high levels of free thyroxine (fT4) developed in 3.5% of the population with normal hormone levels pre-CCTA but without any increased thyroid-related symptoms compared to the remaining cohort. Elevated TPOab and being born outside Sweden were risk factors for developing subclinical hypothyroidism. The presence of thyroid nodules was not associated with ICM-induced thyroid dysfunction.

Conclusion

The results of this prospective study support the notion that in iodine-sufficient countries, ICM-associated thyroid dysfunction is rare, usually mild, self-limiting and oligo/asymptomatic in subjects aged 50–65 years.
Dissipativity of dynamical systems on time scales and the relationship between dissipative differential and dynamical systems
Authors: Tsan V.B. , Stanzhytskyi O.M. , Kapustian O.A.
Published: October 2024

This work is devoted to study the dissipativity property of dynamical systems on time scales and relationship between the dissipativity of systems of dynamic equations on time scales and the corresponding systems of ordinary differential equations. It is established that the dissipativity property is preserved when transitioning from equations on time scales $\mathbb{T}_\lambda$ to the corresponding ordinary differential equations and vice versa, provided that the graininess function $\mu_\lambda$ converges to zero as $\lambda\to0$.
Sesgos y barreras que enfrentan las mujeres en la ciencia
Authors: Hernández Pinzón Aura Melissa
Published: October 2024

Las universidades de la Orinoquía se han convertido progresivamente en una plataforma de desarrollo de la región. Sin embargo, es necesario continuar fortaleciendo las redes académicas que permitan el acceso a una “educación inclusiva y equitativa de calidad [que promueva] oportunidades de aprendizaje permanente para todos en América Latina y el Caribe”[1], éstas constituyen aportes para la comprensión de los problemas del territorio y sus oportunidades. Para tales efectos se busca la consolidación de la red de humanidades de la Orinoquía en la modalidad de Coloquio permanente de ciencias sociales y humanas como respuesta a la necesidad de la región y de la agenda 2030. El Coloquio Permanente de Ciencias Sociales y Humanas es un evento organizado por el Departamento de Humanidades y Formación Integral de la Universidad Santo Tomás seccional Villavicencio con el liderazgo del Grupo de investigación Humanidades digitales, formación y construcción de paz territorial (ÁBA). La presente versión es realizada en alianza con la Universidad de San Buenaventura Bogotá. Un evento dirigido a investigadores, docentes y toda la comunidad académica Nacional e internacional que busca lograr el intercambio de conocimiento y experiencias útiles a los temas propios de las Ciencias Sociales y Humanas, los proyectos de investigación y sus diferentes modalidades.
La persona jurídica: la teoría tridimensional en el sujeto de derecho colectivo
Authors: Agurto Gonzáles Carlos Antonio
Published: October 2024

In this present study, the legal person is analyzed, through the various approaches that have tried to explain its nature, to subsequently study the Three-Dimensional Theory of Law in the legal person and the company, as subjects of law, who are charged with subjective legal situations, rights and duties. Likewise, the three-dimensional approach of the institution of “lifting the veil” as a consequence of illegal acts carried out by this subject of law is studied. Finally, as a result of the work, it is considered that the three-dimensional theory of Law is adequate to understand the legal entity.
Aproximaciones al test de ponderación en la jurisprudencia nacional peruana
Authors: Callañaupa Escobar Nerio Jorge
Published: October 2024

In this article we examine how the Peruvian Constitutional Court has imported the theoretical categories of German jurisprudence and then applied them to its cases, precisely the logic of the weighing test, its structure and its solvency format in the face of a case of collision of rights. fundamental. Along these lines, an examination is made of the main jurisprudence that the Constitutional Court has issued, to break into the semantic field of the proportionality test, thus installing a new element to the hegemonic legal culture of our country, finally adopting the test of proportionality. weighting against the ranking test.
Implicancias jurídicas de la neurotecnología omnipresente e inteligencia artificial en la Cuarta Revolución Industrial: los neuroderechos emergentes
Authors: Charaja Bejar Wilder Luis
Published: October 2024

The Fourth Industrial Revolution is giving rise to legal implications of various kinds, however the one generated by the combination of ubiquitous neurotechnology and artificial intelligence is more transcendental, since this neurorevolution by enabling the extraclinical exploitation of brain data poses challenges for human rights, since that expose individuals to intrusion into the most intimate aspects of their private lives, the risk of having their data hacked, interference with confidentiality and digital surveillance. Therefore, in the context of Industry 4.0 or Industrial Revolution Stage Four, the need to guarantee emerging neurorights related to cognitive freedom, mental privacy, mental integrity and psychological continuity through specific regulations is evident. Furthermore, the consolidation of such neurospecific rights or rights of the mind is a recommendation of specialized academia and a concern of human rights organizations, which must be addressed before it is too late.
Tratamiento tributario de las criptomonedas en el Perú
Authors: Manrique Cervantes José Antonio
Published: October 2024

Cryptocurrencies are digital intangibles, whose use has become widespread and their value has increased exponentially in recent years. However, despite more than a decade having passed since its creation, there is little regulation around cryptocurrencies; and, in particular, with regard to tax law, it is practically nil.Now, although in Peru there are still no specific tax regulations on cryptocurrencies, it is possible that some taxes, due to their general nature, are levied on some types of operations carried out with cryptocurrencies. This article seeks to identify the nature of cryptocurrencies and, based on this, verify whether the operations carried out with these assets fit into the income tax and general sales tax regulations. , in order to determine if some cryptocurrency operations are taxed in Peru.
Violencia familiar en el Perú por agresión física e incompatibilidad de caracteres
Authors: Páez Advíncula Rafael Roosell , Cano Gamero Mirko Dino
Published: October 2024

The research allows analyzing trends, differences and patterns in these cases to strengthen measures to prevent, protect and address family violence in the country. To analyze and understand the incidence of complaints of family violence due to physical aggression and incompatibility of characters in Peru, between 2011 and 2022. A quantitative approach was established to address awareness of this social problem and promote effective measures through statistical and inferential analysis. The findings highlight the importance of strengthening protection measures, promoting education and improving reporting systems. It highlights the need for an integrated and coordinated approach to family violence to prevent and address this serious social problem. Statistical analysis shows significant trends in physical aggression, emphasizing the need for preventive and protective measures. The data collected allows for the identification of patterns and variations in reporting, helping to understand the impact of family violence in Peru. The study emphasizes the importance of strengthening protective measures, promoting education and effectively addressing this social problem. This allows the implementation of public policies and programs that address the root causes of family violence, promoting safe and healthy environments.
Konsep Mar’atun Salihah dan Implementasinya pada Mahasantri Ma’had al-Jami’ah
Authors: Alami Syifaul , Zalida Wardhia , Najwa Alilah
Published: October 2024

Being a woman is a natural thing that must be appreciated, because Islam highly upholds the rights and dignity of women. However, being a woman can be a disaster or a blessing, because women can be the key to heaven but can also be an extraordinary trial if we ignore our obligations as women in Islam. The purpose of this study is to explain the concept of mar'ah sholihah in Islam and find its implementation in students in the current era. To become a pious woman requires knowledge and a strategy and deep sincerity. Women in Islam have special virtues and positions. Position as a creation of Allah, child, wife, and even a mother. The method used is descriptive qualitative, namely describing the concept of mar'ah salihah and analyzing its implementation in students of the Ma'had al-Jami'ah. This study produces findings regarding the main concept of mar'ah sholihah, namely loyalty, obedience, and responsibility of women in carrying out religious orders
Pentingnya Kecerdasan Emosional Untuk Kesiapan Bermoderasi
Authors: Afifah Lia Nur , Shalikhah Putri Ramadhani
Published: October 2024

Tujuan penelitian ini adalah untuk menjelaskan pentingnya kecerdasan emosional dalam kesiapan menerapkan moderasi beragama. Kecerdasan emosional adalah salah satu kecerdasan di samping kecerdasan intelektual dan kecerdasan spiritual yang harus dikembangkan oleh setiap individu. Terlebih dalam penerapan dan pembiasaan moderasi beragama yang beberapa waktu terakhir ini gencar digaungkan oleh Kementerian Agama Republik Indonesia. Moderat identik dengan selalu berusaha mengambil jalan tengah (wasathiyah) dan tidak bersikap ekstrem. Metode yang digunakan adalah kualitatif analisis deskriptif. Dengan adanya kecerdasan emosional yang matang maka seorang individu akan mampu mengadakan hubungan sosial yang harmonis dan dinamis karena ia mampu bere pati dan memiliki ketrampilan sosial yang baik. Hubungan sosial yang harmonis menjadi modal utama dalam membiasakan dan menumbuhkan praktik moderasi di masyarakat Indonesia yang beragam ini sehingga akar-akar konflik yang biasanya dimulai dari perbedaan dapat diminimaoisasi bahkan dihapuskan. Hasil penelitian ini menemukan bahwa kecerdasan emosional berupa kemampuan mengendalikan diri, menyelesaikan masalah, beradaptasi, berkomunikasi dengan baik, berdampak positif terhadap kesiapan seseorang dalam menjalankan moderasi beragama.
Analisis Manfaat dari zingiber officinale Sebagai Pengobatan Alternatif dan Sebagai Tanaman Obat di Dalam Al-Qur’an dan Hadist
Authors: Rohaedi Edi , Majidi Fathul , Mahtama Reza Resky
Published: October 2024

: Jahe telah lama dikenal memiliki berbagai manfaat bagi kesehatan dan telah digunakan dalam berbagai praktik pengobatan tradisional di seluruh dunia. Artikel ini menyajikan pandangan jahe dari berbagai sudut pandang, termasuk kegunaan agama, ilmiah, dan pengobatan alternatif. Dari sudut pandang agama, Al-Qur'an mengakui jahe sebagai salah satu tanaman obat alami yang disebutkan dalam ayat-ayat Al-Qur'an. Hadits tersebut juga menggarisbawahi manfaat jahe sebagai obat yang mujarab, terutama dalam memperkuat lambung dan mengatasi gangguan pencernaan. Dalam pengobatan tradisional, jahe digunakan untuk meringankan berbagai penyakit seperti gerd, radang sendi, rematik, dan nyeri otot. Senyawa aktif dalam jahe seperti gingerol dan shogaol terbukti memiliki sifat antiinflamasi, antioksidan, bahkan antikanker. Dari segi ilmiah, jahe diketahui mengandung berbagai senyawa aktif seperti minyak atsiri, gingerol, dan shogaol yang memiliki efek farmakologis yang bermanfaat bagi kesehatan. Senyawa inilah yang memberikan manfaat pada jahe seperti antiradang, analgesik, dan penambah sistem kekebalan tubuh. Penggunaan jahe sebagai imunomodulator juga telah diteliti dan hasilnya menunjukkan bahwa jahe dapat meningkatkan sistem kekebalan tubuh dan membantu melawan infeksi. Namun konsumsi jahe sebaiknya seimbang dan dalam jumlah yang tepat untuk menghindari efek samping negatif. Secara keseluruhan jahe mempunyai potensi besar sebagai obat yang dapat membantu dalam pengobatan berbagai penyakit dan menjaga kesehatan secara holistik. Dengan pemahaman menyeluruh mengenai manfaat dan risiko penggunaannya, jahe dapat menjadi tambahan yang berharga untuk layanan kesehatan berkelanjutan