bluuebunny/crossref_metadata_2025 huggingface dataset:
Posicionamientos intersubjetivos entre investigadores en el contexto de la publicación académica como práctica social
Authors: Canto Reyes Ana Silvia
Published: February 2025

Este trabajo analiza las formas en que investigadores se posicionan en relación con sus pares según sus prácticas y concepciones de publicación académica. Desde un enfoque crítico se revisa un corpus de entrevistas a profesores-investigadores de universidades públicas mexicanas.
Se emplea el sistema de valoración de Martin y White para examinar los recursos dialógicos y evaluaciones positivas o negativas que los entrevistados emplean al representarse a sí mismos y a otros. El análisis permitió identificar dos perfiles construidos de manera prosódica en la caracterización del comportamiento propio y ajeno: el perfil no íntegro y el perfil discriminador. Estos son representativos de algunas de las consecuencias no deseadas de los mecanismos de evaluación del mérito académico con base en la productividad, y los posicionamientos que los entrevistados asumen al representarlos son indicativos de algunas de las formas en que este sistema se ha visto perpetuado a pesar del descontento que genera.
IA en el mundo de las artes: un análisis crítico de las comunidades creativas que trabajan con Machine Learning y los efectos de la tecnología en la producción artística
Authors: Alonso Martínez Hector , Jarquín-Ramírez Mauro , Díez-Gutiérrez Enrique Javier
Published: February 2025

Este artículo explora la intersección entre la inteligencia artificial (IA) y el arte contemporáneo, analizando cómo la IA redefine la creatividad, la autoría y las dinámicas sociales en la producción artística, así como sus implicaciones éticas y estéticas. Se realiza una revisión crítica de la literatura sobre la incorporación de la IA en el arte, abordando tres niveles de análisis: la comunidad técnica, el mundo del arte y las ciencias cognitivas, para entender sus interacciones y sus efectos en la creatividad. Se identifican tensiones entre la creatividad humana y la actividad de las máquinas. De allí se destaca cómo la IA puede democratizar el acceso a herramientas artísticas, pero también se plantean desafíos sobre la autenticidad y el valor del arte producido por humanos frente al de las máquinas. El estudio concluye que es esencial incluir diversas voces en el desarrollo de IA para mitigar sesgos y redefinir conceptos de creatividad y autoría en un contexto posthumanista.
História Transviada e suas comunidades de intelectuais – uma paisagem historiográfica a partir da Análise de Redes Sociais
Authors: Canabarro Ronald , Affanador-Llach Maria José
Published: February 2025

No presente artigo, apresentamos uma paisagem historiográfica utilizando a Análise de Redes Sociais (ARS) como metodologia, destacando a formação de redes de intelectuais através das bancas de avaliação de teses e dissertações da pós-graduação em História no Brasil, no período de 1994 a 2022, em pesquisas que tratam dasdissidências sexuais e desobediências de gênero. Para este estudo, utilizamos os dados disponibilizados pelo projeto História Transviada.Partimos do pressuposto de que, no contexto da profissionalização da carreira de historiador no Brasil, esses profissionais são responsáveis por conferir validade às pesquisas na pós-graduação,bem como pelo reconhecimento da pessoa avaliada como pesquisadora profissional. A aplicação da ARS permite observar que a formação dessas redes é marcada tanto por laços fortes, oriundos de relações de orientação formal, quanto por laços fracos, resultantes de interações mais transitórias, como as participações em bancas de avaliação.
As infâncias na plataforma de videojogos Roblox: transformações e permanências nas formas de jogar e de ser criança
Authors: Josiowicz Alejandra , Rommel Silva Michele Passos
Published: February 2025

O artigo de pesquisa articula as perspectivas teórico-metodológicas dos estudos culturais da infância na América Latina, as humanidades digitais e os estudos de plataformas digitais, com o intuito de examinar formações tecnodiscursivas em ambientes digitais em que se constroem e se reconstroem sentidos sobre as infâncias nos videogames. Para isso, por meio de uma breve introdução aos estudos ulturais da infância na América Latina, as humanidades digitais, a análise do discurso digital e os estudos de plataforma, introduzimos o estudo dos videogames e dos tecnodiscursos em torno da infância neles. Tendo como objetivo estudar as experiências de crianças e adolescentes no âmbito digital, a partir de uma seleção de vídeos e posts em plataformas como TikTok e Youtube, analisamos os discursos em torno da infância e sua presença na plataforma de jogos Roblox, como espaço que oferece possibilidades para estudar a participação das infâncias na construção de sentidos sobre o ser criança no entorno digital, e rastreamos as transformações e permanências nas formas de conceber as culturas infantis que ali emergem.
Aplicación de la confianza legítima como principio, valor y regla en el campo del derecho constitucional colombiano y administrativo
Authors: Rodríguez Forero Nicolás David
Published: February 2025

El presente artículo identifica el radio de acción y de aplicación de la confianza legítima, como un elemento vinculante y de interpretación hacia la construcción jurídica y constitucional, adoptada en el escenario social colombiano, bajo las fases de principio, valor y regla, a fin de establecer un alcance hacia la consolidación de las relaciones de voluntariedad que existen entre los particulares, la administración y las autoridades, permitiendo un acto de interacción hacia los grupos poblacionales, catalogados como sujetos de protección constitucional a partir de las visiones jurisprudenciales contempladas por la Corte Constitucional y el Consejo de Estado.
Explorando la diversidad cultural: vivencias de comunidades indígenas
Authors: Diaz Ducuara Ana Milena , Ortiz Quevedo Jenny Patricia
Published: February 2025

La universidad es escenario de diversidad cultural y, por lo tanto, de construcción de tejido social, es así como permite el encuentro de corporalidades en el sentido característico de aquellos rasgos que la hacen perteneciente a un grupo poblacional o una comunidad específica, entendido ello, si bien el espectro universitario requiere cambios que den respuesta a los retos actuales, comprendiendo la diversidad cultural y poblacional que allí confluye.
En consecuencia, el objetivo se basa en comprender la experiencia de estudiantes de comunidades indígenas, identificando sus vivencias y posibles barreras que enfrentan en su proceso de educación superior, lo cual permitió recoger testimonios y relatos de los propios estudiantes, desde un enfoque y metodología cualitativa. A partir de lo cual, se resalta la importancia de los pares estudiantiles como construcción colectiva y de apoyo emocional, asimismo, se sugirió el desarrollo de ejercicios interculturales que demanden la confluencia de todos los agentes educativos, se resaltó el interés por asociar su perfil profesional a las situaciones que viven en su comunidad y también se consideró de vital importancia reconocer la diversidad que componen los ambientes educativos, de tal manera que promuevan la interculturalidad como valor enriquecedor para la sociedad.
Derechos humanos: Utopía de la pobreza. Aproximación teórica a la pobreza, como factor que vulnera los derechos humanos
Authors: Becerra Niño Diana Carolina , Borja Viasus Linson Andrés
Published: February 2025

Este artículo es un análisis de tipo teórico, el cual reflexiona acerca de la pobreza y su incidencia en la vulneración de los derechos humanos, razón por la cual estos representan más una utopía que una realidad concreta o puntual para las personas que viven en esta situación. En este sentido, el abordaje de los elementos conceptuales implicó un análisis subjetivo, considerando que no se pueden relativizar, pues responden a interpretaciones no deterministas y a lecturas de realidades diversas. Además, se hizo hincapié en la necesidad de establecer un punto en común entre ellos, como punto de partida para desarrollar los objetivos propuestos.
Por consiguiente, se llevó a cabo una reflexión teórica sobre cinco categorías conceptuales para respaldar este trabajo de investigación: pobreza, utopía, derechos humanos, dignidad y exclusión social. En lo que respecta al concepto de pobreza, se estableció como un factor principal de vulneración de los derechos humanos, pues reduce las posibilidades y el desarrollo de las capacidades sociales, económicas y culturales de las personas, impidiéndoles vivir con dignidad.
La seguridad ciudadana como derecho esencial. El cambio de paradigma
Authors: Toledo Jerez Gustavo Ernesto
Published: February 2025

Colombia tiene problemas de seguridad, desbordados en todas las modalidades existentes: un conflicto armado interno, delincuencia de cuello blanco, además de organizaciones criminales que operan desde las esferas cibernéticas, otras con fines de narcotráfico y control territorial, pero además delincuencia común, se encuentra que los gobiernos han mantenido una política criminal sin sustento, basados en la represión y la prevención general como símbolo y sustentados en la doctrina del enemigo interno (Suescún, 2014), y el devenir del conflicto armado.  Actualmente, el país pasa por una transición del modelo político y económico que promete dar un enfoque distinto del manejo de la política criminal.
El presente trabajo pretende demostrar que la política de seguridad del Estado ha fracasado. Sostiene también que la criminología aplicada es la herramienta de tratamiento del crimen, el cual, permite explicar y establecer las causas, pero también los controles y tratamientos efectivos a los fenómenos criminógeno colombiano, del delincuente, de la víctima y del control social, para atender, de manera integral, los fines de la pena, y así el Estado pueda sustentar sus decisiones en materia de política y consecuente instrumentalización a través del Derecho Penal.
Para comenzar, se abordará el fenómeno de la seguridad desde una perspectiva histórica, con el objeto de exponer circunstancias y consecuentes acciones que han tomado los gobiernos colombianos. Acto seguido, se abordará el estado del arte de la política de seguridad, atendiendo a las conclusiones, opiniones y recomendaciones de los diferentes informes y estudios de las diferentes agencias privadas y públicas. Luego, con una mirada comparada entre la legislación de la unión europea y el colombiano, se evidenciaron las diferentes tendencias socio-políticas, con el objeto de concluir sobre la necesidad de la implementación de la criminología en el ordenamiento jurídico colombiano, como herramienta de fundamentación de la política criminal para atender la garantía de la seguridad ciudadana del Estado Colombiano.
El posacuerdo y Paz Total. Entre la guerra y la violencia criminal
Authors: Medina Gallego Carlos
Published: February 2025

Este artículo surge en el contexto del desarrollo del proyecto de investigación, el cual busca dar razón por la transformación del conflicto en el desarrollo del posacuerdo del año 2016 y el surgimiento de la política de Paz Total, a través de la Ley 272 del 2022, que tiene como objeto definir la política de paz como una política de Estado.
El concepto de Paz Total convoca una reflexión que está mucho más allá de las estrategias y los procedimientos que deben seguirse, para poner fin a los ciclos de violencia y guerra que ha vivido el país; es un concepto que toma en consideración lo anterior, pero se extiende a una concepción integral de paz, la cual se fija como propósito las posibilidades de establecer una sociedad que se erija sobre un modelo de construcción social e institucional de bienestar general, ejercicio pleno de derechos, democracia efectiva y convivencia pacífica. El artículo busca hacer las precisiones conceptuales básicas para el entendimiento del concepto y aborda las dinámicas de diálogo y conversaciones derivadas de él.
Les sécrétions d'arbres (1ère partie)
Authors: Serier Jean-Baptiste
Published: February 2025

Beaucoup d'arbres et de plantes « pleurent ». Ces larmes, produits d'excrétion ou exsudats d'origine soit naturelle, soit pathologique, se présentent sous forme liquide, molle et élastique ou dure. Mais, en fait, que sont ces gommes, ces résines, cette gutta-percha, ce balata, cette gomme à mâcher ou chicle, ces laques, ces baumes ? L'article aborde les thèmes suivants : caoutchouc naturel, gutta-percha et balata, chewing-gum, gommes, résines naturelles (térébenthine de Bordeaux, mastic, le copal, les ambres, la dammar et les laques).
Matériel de carbonisation. Four de carbonisation type Magnien
Authors: Rédacteur de la revue Bois et Forêts des Tropiques
Published: February 2025

Le four à carbonisation inventé en 1922 par M. Magnien a connu une large diffusion. Il est simple de conception et mobile. Cet équipement reste de nos jours très compétitif. L’article présente ses caractéristiques, la méthode de construction, la mise en œuvre et la conduite d’une carbonisation, les améliorations techniques envisageables, et les résultats de carbonisation.
SKPNet: snake KAN perceive bridge cracks through semantic segmentation
Authors: Ruan Yudi , Wang Di , Yuan Yijing , Jiang Shixin , Yang Xianyi
Published: February 2025

As the demands for ensuring bridge safety continue to rise, crack detection technology has become more crucial than ever. In this context, deep learning methods have been widely applied in the field of intelligent crack detection for bridges. However, existing methods are often constrained by complex backgrounds and computational limitations, struggling with issues such as weak crack continuity and insufficient detail representation. Inspired by biological mechanisms, a dynamic snake convolution (DSC) with tubular offsets is incorporated to tackle these challenges effectively. Additionally, a channel-wise self-attention (CWSA) mechanism is introduced to efficiently fuse multi-scale features in U-Net, significantly enhancing the ability of the model to capture fine details. In the classification head, the traditional linear layer is replaced with a Kolmogorov-Arnold network (KAN) structure, which strengthens the robustness and generalization capacity of the model. Experimental results demonstrate that the proposed model improves detection accuracy, achieving a mean intersection over union (mIoU) of 0.877, while maintaining almost the same number of parameters, showcasing exceptional performance and practical applicability. Our project is released at https://github.com/ruanyudi/KanSeg-Bi .
Impact of Nonlinear Diffusion and Heterogeneity on Competing Populations Dynamics
Authors:   Don State Technical University, Budyansky A. V. ,   Southern Federal University, Tsybulin V. G.
Published: February 2025

The impact of migration effects on the formation of population distributions is studied. We consider the model of interplay between two species (resident and invader), and apply the theory of cosymmetry to classify different population scenarios. The system of reaction – diffusion – advection equations is used to describe the nonlinear diffusion and taxis because of nonuniform distribution of the resource. The logistic law of growth is taken to model local interaction between species. We consider a one-dimensional habitat with no-flux boundary conditions. Finite-difference discretization with a staggered grid is used for the spatial coordinate and Runge – Kutta integrator to solve the resulting system of ordinary differential equations of large order. A computer experiment is applied to analyze the dynamics of populations and migration fluxes. We numerically build the maps of migration parameters for description scenarios of invasion and competition. It is found that nonlinear diffusion has an influence on invasion because intraspecific taxis compensates nonoptimal migration to resource. Negative coefficients of intraspecific taxis stimulate diffusion for both species and prevent excessive concentration of populations. This aids the coexistence of species as stationary distributions. Different coefficient signs imply the implementation of corresponding stable semipositive solutions. Direct numerical experiments show that the coexistence of species occurs at large positive coefficients of intraspecific taxis. The dependence of the scenario on the initial distributions is established.
Developing Rahmatan lil 'Alamin-Based Islamic Religious Education in Indonesian Higher Education
Authors: Setiawan Rahmadi Agus
Published: February 2025

This article examines approaches for advancing Islamic Religious Education (IRE) in higher education, centered on the principle of rahmatan lil 'alamin (mercy to all creation). It underscores the critical role of embedding values such as moderation, tolerance, social justice, and compassion within a curricular framework. Employing a qualitative literature review methodology, the study elucidates the foundational tenets of rahmatan lil 'alamin, identifies systemic barriers to its application, and advances actionable approaches for its pedagogical integration. Findings reveal that systematically incorporating these values into IRE can foster inclusive, moderate, and globally conscious students. Nevertheless, persisting challenges impede progress, including institutional resistance to curricular reform, educators’ limited grasp of the concept’s nuances, and sociopolitical pressures shaping policy. To mitigate these issues, the article recommends modernizing curricula to align with evolving societal demands, enhancing educators’ pedagogical capacities through targeted professional development, and fortifying institutional frameworks to reinforce value-based education. By pursuing these approaches, Islamic education can address contemporary global challenges and nurture a generation dedicated to peace and universal welfare, thereby enriching academic discourse on reimagining religious education for the modern era.
Manuskrip Mushaf Al-Qur`an Kertas Kuno (MMKK-A) Koleksi Museum Jenang dan Gusjigang Kudus Jawa Tengah Kajian Kodikologi dan Rasm Berkaidah Hamzah
Authors: Humam Abdul Wadud Kasful , Najihah Vina Tsuroyya
Published: February 2025

Penelitian ini mengkaji Manuskrip Mushaf al-Qur`an Kertas Kuno A (MMKK-A) koleksi dari Museum Jenang dan Gusjigang Kudus. Tujuan dari penelitian ini untuk mendeskripsikan bentuk fisik naskah melalui aspek kodikologi, dan analisis teks dengan mengambil fokus kajian pada rasm berkaidah hamzah dengan klasifikasi ittīfāq dan ikhtilāf baina al-syaikhaini. Klsifikasi ini digunakan untuk menganalisis pola penulisan yang digunakan oleh penulis manuskrip MMKK-A dengan sampel surah dan ayat secara random. Kajian manuskrip penting dilakukan, sebagai upaya untuk menelaah cara penyajian penulisan al-Qur`an masa lampau serta membuka wawasan bagi masyarakat luas agar mengenal dan memahami mushaf-mushaf klasik Nusantara. Kajian ini menggunakan teori tekstologi dan kaidah rasm rumusan Abū Amr al-Dāni dan Abū Dawūd Sulaimān al-Najāh yang kemudian populer dengan sebutan shaikhāni fī al-rasm. Hasil dari peneitian ini mengungkapkan bahwa Manuskrip Mushaf al-Qur`an Kertas Kuno A (MMKK-A) ditulis sekitar abad ke 18-19 M menggunakan kertas Eropa dengan model penulisan berupa khat naskhi. Naskah ini terdiri dari 30 Juz yang dijilid menggunakan benang, dengan ukuran panjang 33 cm x lebar 22,5 cm. Sedangkan pada analisis teks, analisis rasm berkaidah hamzah secara umum sesuai (ittīfaq) dengan kaidah yang dirumuskan oleh shaikhāni fī al-rasm, dan beberapa kata menyalahi rumusan salah satunya (ikhtilaf baina aḥadhihima).
Legitimasi Penafsiran DI/TII Sensen Komara tentang Perubahan Arah Kiblat: Analisis Penafsiran QS. Al-Baqarah 142-144
Authors: Muhammad Hafid Nur , Sekardila Tasya , Dahtiana Tia
Published: February 2025

Interpretations with pragmatic and ideological approaches to Qur'anic verses have the potential to trigger deviations in people's understanding. Sensen Komara uses this interpretation to strengthen the ideology and legitimacy of his movement, which has the potential to cause division among Muslims. This study aims to analyze the methods and approaches used by Sensen Komara to examine the legitimacy of Sensen Komara's interpretation of the change in Qibla direction contained in QS. Al-Baqarah verse 142-144, as well as comparing it with authoritative interpretations from leading scholars. The research conducted is library research, namely by collecting library data. This research uses a qualitative-descriptive-analytical method by explaining or describing through clear words and detailing systematically, factually and accurately based on existing data. The interpretation of QS. Al-Baqarah 142-144 by DI/TII Sensen Komara reflects an attempt to use the Qur'an as a means of legitimizing the ideology of their movement. This pragmatic and ideological approach shows the courage to adapt the sacred text according to the context of their struggle. Interpretations that tend to be partial and contextually limited risk ignoring the universal and inclusive dimensions of Qur'ānic verses. As a consequence, the deep spiritual message of changing the Qibla direction as a symbol of Muslim obedience and unity can be reduced to a mere political tool. This interpretation shows the importance of a balance between understanding the historical context and the universal message of the Qur'an.
Inteligencia emocional como mediadora de la ansiedad y el bienestar psicológico en el proceso de duelo
Authors: Delhom Peris Iriada , Mateu-Mollá Joaquín , Donio-Bellegarde Mônica , Lacomba-Trejo Laura
Published: February 2025

Introduction. The loss of a loved one can lead to anxiety symptoms, which negatively affect people's well-being. However, appropriate emotional management plays a protective role against psychopathology and can increase psychological well-being (PWB). This study explores the mediating relationship of emotional attention, clarity and repair on the impact of anxiety on the PWB of people who have recently lost a relative.
Method. Validated scales were used to assess anxious symptomatology (DASS-21), emotional intelligence (TMMS-24), and PWB (Ryff) in a sample of 97 people with a mean age of 40.71 years (SD = 12.58), 79.40% of whom were women. Descriptive statistics, Pearson's bivariate correlations, and mediation analyses were performed.
Results. Moderate negative correlations were found between anxiety and PWB, and negative and moderate associations between anxiety and clarity and between anxiety and repair. Attention was positively related to anxiety. Full or partial mediating effects of components of emotional intelligence were found in the inverse relationships between anxiety and most dimensions of PWB.
Conclusions. These results reinforce the key role of emotional skills in alleviating the psychological pain of people who have experienced the death of a relative.
Archaeal LOV domains from Lake Diamante: first functional characterization of a halo-adapted photoreceptor
Authors: Valle Lorena , Coronel Yonathan J. , Bravo Guillermina E. , Díaz Joaquín A. , Albarracín Virginia H. , Farías María E. , Abatedaga Inés
Published: February 2025

High-altitude Andean lakes (HAALs) represent polyextreme environments where diverse photoinduced processes have been documented. In this study, we investigated Light-Oxygen-Voltage (LOV) photoreceptors and identified 28 archaeal sequences from Lake Diamante, which were classified into two major groups (A and B), with three outliers showing unique structural features. Analysis of these sequences and their 3D models revealed hallmark adaptations to halophilic environments, including an abundance of surface acidic residues, an increased prevalence of arginine over lysine, and a greater density of salt bridges. The heterologous expression of a representative LOV domain, ALovD-1, demonstrated conserved photophysics between its dark- and light-adapted states, which was consistent with the slow cycling type. Importantly, ALovD-1 exhibited remarkable halophilic characteristics, maintaining photocycling functionality at salt concentrations as high as 3 M monovalent salts. This ability can be attributed to discrete structural changes, allowing adjustments in flavin interactions within its cavity under varying ionic strengths. Mutational studies of key residues (Y30F and Y48F) highlighted their roles in modulating flavin photophysic and revealed a stabilizing function for Y48 at low salt concentrations. These findings mark the first functional characterization of a canonical archaeal LOV domain, expanding our understanding of light sensing and protein adaptation in extremophiles.
Artificial Intelligence and Machine Learning-Based Prediction of Cardiovascular Disease Risk in Rural Elderly Women in North-East India: Insights into Women's Health, HDL, Metabolic Syndrome, and Key Biomarkers
Authors: Ghosh Joyeta , Chaudhuri Tinni , Taneja Jyoti , Kant Ravi
Published: February 2025

Background: This study aimed to leverage artificial intelligence and machine learning approaches to predict cardiovascular disease (CVD) risk among rural postmenopausal women in North-East India. The objectives included identifying critical risk factors and evaluating the performance of various machine learning models to enhance CVD prediction accuracy in rural populations.
Methods: The research was conducted in Singur Block (West Bengal) and Amdanga Block (North 24 Parganas District) over a span of four years, from March 2014 to August 2018. Key risk factors, including waist circumference, blood pressure, fasting blood glucose, and HDL cholesterol, were collected and analyzed. A correlation matrix was employed to assess the associations between these variables and CVD risk. Additionally, eight machine learning models were deployed to predict CVD risk, with performance comparisons to identify the most effective algorithm.
Results: The correlation analysis revealed strong associations between CVD risk and factors such as waist circumference, blood pressure, and fasting blood glucose, with HDL cholesterol playing a lesser yet relevant role. Among the machine learning models tested, the Random Forest algorithm achieved the highest accuracy of 98.91%, followed by Decision Tree and Support Vector Classifier (SVC), both of which achieved accuracies exceeding 95%. Feature important analysis highlighted waist circumference as the most significant predictor, with blood pressure and fasting blood glucose also contributing substantially to the prediction of CVD risk, while HDL cholesterol had a comparatively lower but still notable impact.
Conclusion: Machine learning techniques, particularly the Random Forest model, demonstrated remarkable efficacy in predicting CVD risk among rural postmenopausal women. This study identifies waist circumference, blood pressure, and fasting blood glucose as key predictors, emphasizing the potential of machine learning-based approaches as cost-effective, scalable solutions for early CVD detection. These findings provide a foundation for targeted preventive measures and improved health outcomes in underserved rural settings.
Impact of Living Arrangements on Burnout, Loneliness and Substance Use among Kazakhstan University Students
Authors: Mynbayeva Aigerim , Stelmakh Svetlana , Satkangulova Gulnara , Sarkisyan Liliya , Reznik Alexander , Isralowitz Richard
Published: February 2025

Kazakhstan is a large Central Asian country of the former Soviet republic with a population of 19 million, the majority being Muslim with moderate religious practices. Despite considerable economic growth, most university students remain pressed to address higher education and living costs. This cross-sectional study of 2,065 students examined living conditions and its association with burnout, loneliness and substance use. Female students, and those using harmful substances, were more likely to report burnout and loneliness. Gender status did not differentiate student substance use. However, students who live on or off campus evidence more substance use including alcohol binge drinking. Regardless of gender status and living conditions, religious students reported less substance use. Study findings contribute to usable information for promoting university student psychological well-being through policy and prevention practices associated with substance use over time and across locations in the country.
Molecular Docking Studies for the Evaluation of Cannabinoids as Multi-Target Inhibitors of Type 2 Diabetes
Authors: Takuissu Guy Roussel , Ambamba Dupon Bruno , Iqbal Shabnor , Olofinsan Kolowole , Tchinda Cedric Fossi , Ella Fils Armand , Ngnameko Corinne Raissa , Ngoumen Dany Joel , Motlalepula Matsabisa Gilbert
Published: February 2025

Type 2 Diabetes is due to dysregulation of glycemic control through multiple mechanisms. Cannabinoids from Cannabis sativa L. show promise as anti-diabetic agents, though currently their molecular mechanisms are unclear. This study carried out in silico molecular docking of cannabinoids (cannabidiol (CBD), tetrahydrocannabivarin (THCV), cannabichromene (CBC), cannabigerol (CBG), cannabinol (CBN), Δ9-tetrahydrocannabinol (THC)) against key diabetes drug targets namely: dipeptidyl peptidase-4 (DPP-4), α-glucosidase, α-amylase and invertase. Enzyme structures were obtained from the RCSB Protein Data Bank, while ligand structures were generated and optimized using ChemDraw. AutoDockTools-1.5.7 determined docking parameters, and Biovia Discovery Studio visualized interaction profiles. Normal mode analysis was performed for molecular dynamics simulations. Cannabinoids used in this study showed higher binding affinities (-5.02 to -7.85 kcal/mol) than reference drugs for the targets, with the exception of DPP-4. For DPP-4, CBN (-7.85 kcal/mol) showed best affinity followed by THC (-6.64 kcal/mol). All cannabinoids interacted with catalytic residues except cannabichromene. For α-amylase, THC (-7.14 kcal/mol) was strongest, with residues Asp197, Glu233, Asp300 involved. Against invertase, THC (-7.27 kcal/mol) had highest affinity interacting with Glu230. For α-glucosidase, THC (-7.86 kcal/mol) again dominated via key residues. Normal mode analysis revealed THC binding modulated complex dynamics differently for each enzyme. This study provides insights into cannabinoids' multi-target binding profiles against important T2D drug targets, supporting their potential as natural anti-diabetic agents requiring further research.
Unlocking Australia’s AI usage in Law enforcement from Human involvement perspective: A Systematic Literature Review
Authors: Dasgupta Rumpa , Mekala Sri Harsha , Jaigirdar Fariha Tasnim , Anwar Adnan , Chang Lennon
Published: February 2025

Exploring human trust in Artificial Intelligence (AI) in Law Enforcement domain is paramount for its ethical and effective deployment. As AI systems become increasingly integrated into society, trust ensures transparency, accountability, and fairness in their deployment. Despite the rapid increase in discussion about AI usage in law enforcement in various sectors globally, no secondary research explores that for OCEANIA, specifically in Australia. Moreover, how humans are considered in AI law enforcement is an uninvestigated area in this region. This paper aims to investigate this gap by systematically exploring various applications used in this region and analysing how human perspectives are used, and to what extent. We conducted a systematic literature review (SLR) based on 56 qualitatively selected studies to i) classify the types, frequency, and demography of published research; ii) explore how AI is leveraged; iii) identify how and to what extent humans are considered in development and applications of AI in law enforcement; iv) understand the challenges and solutions reported in this domain and worldwide. In summary, our findings point to the need for solutions to address operational and ethical issues in integrating AI into law enforcement and for unified legislation or regulations to effectively design and utilize AI in this domain. Based on the findings that highlight the important concerns in this domain, we recommend a list of future research directions.
Effects of pulse period and frequency content of ground motion records on fragility curves of BRBFs
Authors: Yaghmaei-Sabegh Saman , Ranjbari Maryam
Published: February 2025

This study aims to estimate the fragility curves of buckling-restrained braced frames (BRBFs) subjected to pulse-like excitations at collapse prevention (CP) and immediate occupancy (IO) performance levels. To this end, 4, 8, 12, and 15-storey steel frames with mega configuration BRBs were modeled using a finite element approach, and fragility analyses were carried out for the records classified based on pulse period (TP) and the ratio of PGA/PGV (peak ground acceleration to peak ground velocity) as the indicator of frequency content. The result showed that for high-rise BRBFs, collapse probability differences between the records with TP<2s and TP>2s are at least 45% and 25% at the MCE and DBE levels, respectively, in which records with larger TP lead to severe damage. Also, analyses indicated that by increasing PGA/PGV ratio in TP<2s records, collapse probabilities for shorter BRBFs decrease where the highest collapse probabilities could be related to records with PGA/PGV<1g.s/cm.
Polymeric nanomicelles for piperine delivery: Preparation, characterization and evaluation of antioxidant and in-vivo anti-inflammatory properties
Authors: Zare Mahboobeh , Gavzan Hakime , Sarkati Malihe Noruzi , Mobaraki Mohammad Ali
Published: February 2025

Purpose Piperine, one of the bioactive alkaloids, exhibits restricted therapeutic effectiveness owing to its inadequate solubility and bioavailability. Nanomicelles hold great potential as drug delivery systems for drugs with low water solubility. This study aimed to create micelles that contain tragacanth gum, vitamin D, and folic acid to encapsulate piperine.Methods Piperine was isolated from black pepper and subsequently loaded on synthesized polymeric micelles. The antioxidant activity of piperine-loaded micelles was tested by DPPH⋅ radical method. Moreover, the peripheral anti-inflammatory activity of nanomicelles was assessed using the formalin-induced paw edema method.Results According to the results obtained from this investigation, the utilization of nanomicelles demonstrated an enhancement in the radical scavenging activity of piperine, consequently leading to a notable reduction in the required dosage of piperine for its anti-inflammatory effects.Conclusion The findings indicate that the utilization of synthesized micelle as an innovative targeted delivery system could potentially augment the therapeutic characteristics of piperine.
Exploring the anticancer potential of Vitex negundo L.: Cytotoxicity and gene regulation in PA1 ovarian cancer cells
Authors: Govindasamy Manivannan , Anbazhagan Ganesh Kumar , NCJ Packia Lekshmi , R Premkumar , Hirad Abdurahman Hajinur , Karuppiah Ponmurugan
Published: February 2025

Background Ovarian cancer is a commonly occurring and significant health concern among women worldwide. There is an ongoing search for effective and natural therapeutic agents to combat this disease.Objective The study aimed to analyze the cytotoxic effect and gene expression in ovarian cancer (PA1) cell lines treated with methanolic leaf extract of Vitex negundo.Methods The cytotoxic effect of the methanolic leaf extract of Vitex negundo on the ovarian cancer cell line (PA1) was determined using the MTT assay. The IC50 value was calculated to assess the concentration required to inhibit 50% of cell growth. Gene expression analysis was performed using RT-qPCR to evaluate the mRNA levels of significant targets including PLEKHH3, STIP1, and ATP5F1A.Results The IC50 value of the methanolic leaf extract of Vitex negundo on PA1 cells was determined as 53.332 ± 1.449 µg/mL compared to vehicle control cells. RT-qPCR analysis revealed that among the three target genes analyzed, two targets (PLEKHH3 and ATP5F1A) were downregulated, while STIP1 was upregulated upon treatment with the plant extract compared with untreated control cells.Conclusion This study indicates that the methanolic leaf extract of Vitex negundo exhibits cytotoxic effects against ovarian cancer cells and modulates gene expression of key targets involved in cellular processes. These findings suggest potential therapeutic applications of Vitex negundo in the treatment of ovarian cancer.
Comparison of the effectiveness of the common bean fly (Ophiomya spp.) control methods: Implications for resistance breeding: A meta-analysis
Authors: Tsekenedza Shylet , Shimelis Hussein , Nkhata Wilson , Mukankusi Clare M. , Dossa Emeline N.
Published: February 2025

The bean fly (Ophiomya spp.) is one of the most destructive field pests of the common bean (Phaseolus vulgaris L.), notably in Eastern and Southern Africa. Several studies have recommended a range of methods for bean fly control. Nevertheless, the effectiveness of management practices and their impact on grain yield is not fully understood to help prioritize and guide integrated management of the pest spearheaded by host plant resistance. A meta-analysis was conducted involving 18 studies on bean fly control methods. The highest achieved grain yield was 3761.00 kg/ha from the chemical control, and the lowest was 14.10 kg/ha from the genetic control, indicating a low level of bean fly-resistant lines in the current breeding stocks. The control methods had effect sizes ranging from small (0.19) to large (1.38). The chemical and integrated control methods had the highest ES values of 1.21 and 1.38, respectively, but had wide 95% confidence intervals. The metadata suggests variable efficacy of the control methods, and breeding for host resistance is yet to be up-scaled to control the bean fly and bolster grain yield effectively. No studies have reported the effectiveness of biological control against bean fly based on the grain yield of candidate common bean genotypes. Overall, the genetic control method with an ES (0.19) contributed to a relatively small effect, with CIs of -0.8 and 0.56 overlapping the null effect. This suggests that the level of bean fly resistance in the available genetic pool is still low, resulting in low yield potential, which requires concerted breeding.
Exploring the Therapeutic Potential of Momordica charantia in Targeting Protein Kinase C Delta (PRKCD) for Type 2 Diabetes Mellitus: Insights from Network Pharmacology, Molecular Docking, and Molecular Dynamics Simulations
Authors: Yadav Ruchi , Nambiar Nidhi , Shah Manushi , Patel Bhumika
Published: February 2025

Type 2 diabetes mellitus (T2DM) is a chronic condition caused by decreased insulin production and increased insulin resistance, and its prevalence has increased by 49% since 1990. Current treatments for T2DM include pharmacological agents and lifestyle modifications, but they are limited by their side effects and cost. Herbal remedies and natural products have become popular alternative treatments for T2DM as they are associated with fewer side effects. Momordica charantia Linn. (bitter melon) is a member of the Cucurbitaceae family and has been used as a traditional anti-diabetic remedy in various countries for many years. The plant contains several biologically active compounds, including glycosides, saponins, alkaloids, triterpenes, proteins, and steroids. The hypoglycemic activity of Momordica charantia is primarily attributed to its saponins, which are collectively known as charantins, and alkaloids. Through network pharmacology, Molecular docking and MD simulation we found underlying, mechanism of karela in the treatment of T2DM. Through network pharmacology from 49 targets we found the Protein kinase C delta (PRKCD) as a hub gene. Various studies have also indicated the pathophysiological role of PRKCD in the development of T2DM. Gene expression analysis in 24 patients revealed an overexpression of PRKCD in both prediabetic and diabetic patients. Molecular docking data identified the top three active constituents of karela as Momordicoside C, Momorcharaside B, and Momordin I, with docking scores of -8.0 kcal/mol, -7.9 kcal/mol, and − 7.9 kcal/mol, respectively. Additionally,MD simulation was performed using the GROMACS software and we found that Momordicoside C and Momorcharaside B has good stability and also formed the H-bond at end of the 100ns of simulation. This study revelled new mechanism action of a well-known plant karela in the treatment of T2DM.
The Chain Mediation Effects Of Automatic Thoughts And Impulse Control On Growth Mindset And Cognitive Fusion Among Junior High School Students
Authors: Tao WeiDong , Wang BangCheng , Tao XiaoLi
Published: February 2025

Previous research has shown that having a growth mindset can directly or indirectly affect cognitive fusion in college students. Using the Cognitive Behavior Therapy (CBT) framework, this study explores the relationship between growth mindset and cognitive fusion in junior high school students, as well as how impulse control and automatic negative thoughts mediate this relationship.Participants were 520 junior high school students who completed a Growth Mindset scale, Cognitive Fusion questionnaire, self-control scale, and automatic-thought scale. We tested the mediation and chain-mediated models using PROCESS. The results revealed (1) a significant negative correlation between growth mindset and cognitive fusion, and (2) both impulse control and automatic negative thoughts were found to play a chain-mediating role in the relationship between growth mindset and cognitive fusion.These findings highlight the importance of supporting the development of a growth mindset in students while simultaneously addressing their impulse control abilities and patterns of automatic thinking.
Nervous memories and caste trouble
Authors: Barbosa Thiago P.
Published: February 2025

Caste has been a central concept in anthropological theorizations about Indian society. It has been used to explain the cultural diversity and biological variation in the subcontinent as well as the structure that gives India a functioning, cohesive society. But caste has also been looked at through the critical lenses of inequality, as a marker of hierarchy that has justified segregation and cements historical injustices. These different approaches to caste and (anti-)casteism are often in tension in the space of Indian anthropology, a tension that is analogous to the friction between the different approaches to race and (anti-)racism. This paper examines how such tension emerges in the remembrance and commemoration of two central historical figures in Indian anthropology, namely Bhimrao Ramji Ambedkar and Irawati Karve. By tracing the transnational genealogy of these two scholars, I show how their own work on caste was affected by two German figures who represent both sides in a key debate in anthropology, namely the cultural anthropologist Franz Boas (a prominent figure in the school where Ambedkar was trained) and the racial anthropologist Eugen Fischer (Karve’s PhD supervisor). This transnational 'history of the present' of anthropological approaches to caste(ism) aims to contribute to understanding a key question in anthropology, in India as elsewhere: how to deal with the trouble of classifying and conceptualizing human differences and social inequalities.
Constant K. Sarè: Afrikanische Dinge in der deutschsprachigen Literatur. Bielefeld 2023
Authors: Hahn Hans P.
Published: February 2025

Buchbesprechung
Manfred Stoppok: The household energy transition from global and local perspectives. Leipzig 2023
Authors: Streck Bernhard
Published: February 2025

Buchbesprechung
Josef Franz Thiel (1932–2024)
Authors: Raabe Eva
Published: February 2025

Nekrolog
Ute Röschenthaler (1960–2024)
Authors: Diawara Mamadou
Published: February 2025

Nekrolog
Eulogie für Fritz Kramer
Authors: Halfmann Jasper
Published: February 2025

Nekrolog
Fritz Kramer, fremd und freundlich
Authors: Hauschild Thomas
Published: February 2025

Nekrolog
Adressen der Autoren
Authors: Jebens Holger
Published: February 2025

Adressen der Autoren
Veröffentlichungen des Frobenius-Institutes
Authors: Jebens Holger
Published: February 2025

Veröffentlichungen des Frobenius-Institutes
Information for Authors
Authors: Jebens Holger
Published: February 2025

Information for Authors
Overview of instrumental methods used in the field of food analysis
Authors: Rozhdestvenskaya L. N. , Romanenko S. P. , Lomovsky I. O. , Lachugin A. P.
Published: February 2025

The emergence of new technologies for food production and current trends in the use of alternative sources of raw materials require improved approaches to the analysis of the chemical composition of food products. In the course of planning work to carry out analytical research, a number of challenges arise: identification of the research objects themselves; selection of research methods and tools; ensuring the representativeness and validity of the results obtained. When choosing and justifying research methods, it is necessary to rely on a large number of factors, which include both confirmation of the actual composition of food products, including the determination of unintentionally present substances, and the reliability of the data obtained, taking into account the selected instrumental methods. The purpose of this work is to generalize and systematize the essence and characteristics of the main methods of food analysis and evaluate existing approaches to the justification and application of instrumental methods of analysis in relation to new types of food products. This paper reviews the literature on instrumental research methods used to obtain values in the most representative international databases on the composition of food products (FAO/INFOODS Food Composition Databases, USDA NDL, Fineli, Frida), as well as databases of the chemical composition of food products in Russia, Japan and Australia. To search for descriptions and features of the use of analytical equipment and analytical methods, electronic library systems Web of Science, Scopus, Elibrary, ResearchGate, Google Scholar, Microsoft Academic, Science Direct were used. This review highlights the role of various research methods: photometric and electrophoretic, titrimetric, extraction, chromatographic, spectroscopic, immunoenzymatic, as well as those based on the polymerase chain reaction and the use of nuclear magnetic resonance, lateral flow and electropheresis.