bluuebunny/crossref_metadata_2025 huggingface dataset:
Programmable microfluidic genotyping of plant DNA samples for marker-assisted selection
Authors: Zec Helena C. , Zheng Tony , Liu Lingshu , Hsieh Kuangwen , Rane Tushar D. , Pederson Todd , Wang Tza-Huei
Published: March 2018

As demands to maintain the global food production continue to mount, multinational seed companies are turning to new DNA marker technologies to accelerate the rate of plant breeding and crop improvement. The key to widespread adoption of molecular breeding is the availability of flexible and cost-effective tools that can perform combinatorial and high-throughput genotyping of single-nucleotide polymorphisms (SNPs) to guide the crop development process. Toward this end, we have developed a programmable, droplet-based microfluidic device for genotyping maize genomic DNA. A unique feature of the microfluidic platform is the nano sample processors (NSPs), which allow the device to sequentially load an unrestricted number of unique DNA samples using only two inlets, overcoming the current limitation to the number of sample inputs due to small device footprint. Direct and programmable droplet generation within the device allows each sample to be genotyped against a panel of markers on demand. Moreover, we have successfully implemented the Invader assay for SNP genotyping in flowing, 50-nL droplets, thus achieving significant reduction in consumption of reagents per reaction as compared with conventional genotyping platforms. As a demonstration, we performed 240 Invader reactions (testing 8 DNA samples against 10 SNP markers) and achieved greater than 93% accuracy in SNP calling of plant DNA samples in a single droplet-based experiment.
Correction: Publisher Correction: Wave energy budget analysis in the Earth’s radiation belts uncovers a missing energy
Authors: Artemyev A. V. , Agapitov O. V. , Mourenas D. , Krasnoselskikh V. V. , Mozer F. S.
Published: March 2018

Nature Communications 6: Article number: 7143 (2015); Published: 15 May 2015; Updated: 26 March 2018 The original HTML version of this Article had an incorrect article number of 8143; it should have been 7143. This has now been corrected in the HTML; the PDF version of the Article was correct from the time of publication.
Computational discovery of p-type transparent oxide semiconductors using hydrogen descriptor
Authors: Yim Kanghoon , Youn Yong , Lee Miso , Yoo Dongsun , Lee Joohee , Cho Sung Haeng , Han Seungwu
Published: March 2018

The ultimate transparent electronic devices require complementary and symmetrical pairs of n-type and p-type transparent semiconductors. While several n-type transparent oxide semiconductors like InGaZnO and ZnO are available and being used in consumer electronics, there are practically no p-type oxides that are comparable to the n-type counterpart in spite of tremendous efforts to discover them. Recently, high-throughput screening with the density functional theory calculations attempted to identify candidate p-type transparent oxides, but none of suggested materials was verified experimentally, implying need for a better theoretical predictor. Here, we propose a highly reliable and computationally efficient descriptor for p-type dopability—the hydrogen impurity energy. We show that the hydrogen descriptor can distinguish well-known p-type and n-type oxides. Using the hydrogen descriptor, we screen most binary oxides and a selected pool of ternary compounds that covers Sn2+-bearing and Cu1+-bearing oxides as well as oxychalcogenides. As a result, we suggest La2O2Te and CuLiO as promising p-type oxides.
Limitations in predicting the space radiation health risk for exploration astronauts
Authors: Chancellor Jeffery C. , Blue Rebecca S. , Cengel Keith A. , Auñón-Chancellor Serena M. , Rubins Kathleen H. , Katzgraber Helmut G. , Kennedy Ann R.
Published: March 2018

Despite years of research, understanding of the space radiation environment and the risk it poses to long-duration astronauts remains limited. There is a disparity between research results and observed empirical effects seen in human astronaut crews, likely due to the numerous factors that limit terrestrial simulation of the complex space environment and extrapolation of human clinical consequences from varied animal models. Given the intended future of human spaceflight, with efforts now to rapidly expand capabilities for human missions to the moon and Mars, there is a pressing need to improve upon the understanding of the space radiation risk, predict likely clinical outcomes of interplanetary radiation exposure, and develop appropriate and effective mitigation strategies for future missions. To achieve this goal, the space radiation and aerospace community must recognize the historical limitations of radiation research and how such limitations could be addressed in future research endeavors. We have sought to highlight the numerous factors that limit understanding of the risk of space radiation for human crews and to identify ways in which these limitations could be addressed for improved understanding and appropriate risk posture regarding future human spaceflight.
Asbestosis is prevalent in a variety of construction industry trades
Authors: Walters G. I. , Robertson A. S. , Bhomra P. S. , Burge P. S.
Published: March 2018

A diagnosis of asbestosis, which is a long-latency, fibrotic lung disease, has implications for the patient in terms of prognosis, treatment and compensation. Identifying and quantifying asbestos exposure is difficult without a detailed occupational history, and the threshold dose of asbestos required to cause asbestosis is not well understood. We reviewed all cases of asbestosis diagnosed between 2001 and 2016 at the Birmingham Regional NHS Occupational Lung Disease Service to determine the industries and occupations most frequently implicated in causation, in order to help clinicians identify where asbestosis might enter the differential diagnosis for a patient with chronic respiratory symptoms. A variety of construction trades were frequently reported including carpenters and joiners, pipe fitters, laggers, labourers, painters and shop fitters. Traditionally heavily exposed occupations such as shipbuilding were not commonly seen.
Enrichment of ODMR-active nitrogen-vacancy centres in five-nanometre-sized detonation-synthesized nanodiamonds: Nanoprobes for temperature, angle and position
Authors: Sotoma Shingo , Terada Daiki , Segawa Takuya F. , Igarashi Ryuji , Harada Yoshie , Shirakawa Masahiro
Published: March 2018

The development of sensors to estimate physical properties, and their temporal and spatial variation, has been a central driving force in scientific breakthroughs. In recent years, nanosensors based on quantum measurements, such as nitrogen-vacancy centres (NVCs) in nanodiamonds, have been attracting much attention as ultrastable, sensitive, accurate and versatile physical sensors for quantitative cellular measurements. However, the nanodiamonds currently available for use as sensors have diameters of several tens of nanometres, much larger than the usual size of a protein. Therefore, their actual applications remain limited. Here we show that NVCs in an aggregation of 5-nm-sized detonation-synthesized nanodiamond treated by Krüger’s surface reduction (termed DND-OH) retains the same characteristics as observed in larger diamonds. We show that the negative charge at the NVC are stabilized, have a relatively long T2 spin relaxation time of up to 4 μs, and are applicable to thermosensing, one-degree orientation determination and nanometric super-resolution imaging. Our results clearly demonstrate the significant potential of DND-OH as a physical sensor. Thus, DND-OH will raise new possibilities for spatiotemporal monitoring of live cells and dynamic biomolecules in individual cells at single-molecule resolution.
Non-neutralizing Antibody Responses against VP1 in Enterovirus A, B, C and Rhinovirus A species among Infants and Children in Shanghai
Authors: Ding Yingying , Rui Bing , Gao Caixia , Xu Menghua , Wang Lili , Zhao Chunyan , Bai Jie , Wang Jinhong , Xu Jin , Pan Wei
Published: March 2018

The overall non-neutralizing antibody responses against EV infections among infants and children remain unknown. The non-neutralizing antibody responses against VP1 of EV-A species (Enterovirus 71 (EV71), Coxsackievirus A16 (CA16)), EV-B species (Coxsackievirus B3 (CB3)), EV-C species (Poliovirus 1 (PV1)) and RV-A species (Rhinovirus A N13 (RV13)) were detected and analyzed using a novel evolved immunoglobulin-binding molecule (NEIBM)-based ELISA among infants and children aged 1 day to 6 years in Shanghai. The anti-VP1 reactivity against these EVs changed similarly in an age-related dynamic: being high level in the 1–28-day age group, declining to the lowest level in the 1–12-month age group, gradually increasing to the peak level in the 13–60-month age group, and remarkably declining in the 61–72-month age group, which reflects the conversion from maternally-derived to primary antibody responses. The anti-RV13 VP1 antibodies were demonstrated at the highest level, with anti-CB3 and PV1 VP1 antibodies at the second highest level and anti-CA16 and EV71 VP1 antibodies at the lowest level. These findings are the first to describe the overall non-neutralizing antibody responses against VP1 of the EV-A, B, C and RV-A viruses among the infants and children and could be helpful for further understanding the ubiquitous EV infections among children.
Protein-bound NAD(P)H Lifetime is Sensitive to Multiple Fates of Glucose Carbon
Authors: Sharick Joe T. , Favreau Peter F. , Gillette Amani A. , Sdao Sophia M. , Merrins Matthew J. , Skala Melissa C.
Published: March 2018

While NAD(P)H fluorescence lifetime imaging (FLIM) can detect changes in flux through the TCA cycle and electron transport chain (ETC), it remains unclear whether NAD(P)H FLIM is sensitive to other potential fates of glucose. Glucose carbon can be diverted from mitochondria by the pentose phosphate pathway (via glucose 6-phosphate dehydrogenase, G6PDH), lactate production (via lactate dehydrogenase, LDH), and rejection of carbon from the TCA cycle (via pyruvate dehydrogenase kinase, PDK), all of which can be upregulated in cancer cells. Here, we demonstrate that multiphoton NAD(P)H FLIM can be used to quantify the relative concentrations of recombinant LDH and malate dehydrogenase (MDH) in solution. In multiple epithelial cell lines, NAD(P)H FLIM was also sensitive to inhibition of LDH and PDK, as well as the directionality of LDH in cells forced to use pyruvate versus lactate as fuel sources. Among the parameters measurable by FLIM, only the lifetime of protein-bound NAD(P)H (τ2) was sensitive to these changes, in contrast to the optical redox ratio, mean NAD(P)H lifetime, free NAD(P)H lifetime, or the relative amount of free and protein-bound NAD(P)H. NAD(P)H τ2 offers the ability to non-invasively quantify diversions of carbon away from the TCA cycle/ETC, which may support mechanisms of drug resistance.
The p53-S100A2 Positive Feedback Loop Negatively Regulates Epithelialization in Cutaneous Wound Healing
Authors: Pan Shin-Chen , Li Che-Yu , Kuo Chia-Yi , Kuo Yi-Zih , Fang Wei-Yu , Huang Yu-Hsuan , Hsieh Tzu-Chin , Kao Hung-Ying , Kuo Yuan , Kang Ya-Rong , Tsai Wan-Chi , Tsai Sen-Tien , Wu Li-Wha
Published: March 2018

The S100A2 protein is an important regulator of keratinocyte differentiation, but its role in wound healing remains unknown. We establish epithelial-specificS100A2transgenic (TG) mice and study its role in wound repair using punch biopsy wounding assays. In line with the observed increase in proliferation and migration ofS100A2-depleted human keratinocytes, mice expressing humanS100A2exhibit delayed cutaneous wound repair. This was accompanied by the reduction of re-epithelialization as well as a slow, attenuated response ofMcp1,Il6,Il1β,Cox2, andTnfmRNA expression in the early phase. We also observed delayedVegfamRNA induction, a delayed enhancement of the Tgfβ1-mediated alpha smooth muscle actin (α-Sma) axis and a differential expression of collagen type 1 and 3. The stress-activated p53 tumor suppressor protein plays an important role in cutaneous wound healing and is anS100A2inducer. Notably, S100A2 complexes with p53, potentiates p53-mediated transcription and increases p53 expression both transcriptionally and posttranscriptionally. Consistent with a role of p53 in repressing NF-κB-mediated transcriptional activation, S100A2 enhanced p53-mediated promoter suppression ofCox2, an early inducible NF-κB target gene upon wound injury. Our study thus supports a model in which the p53-S100A2 positive feedback loop regulates wound repair process.
Insensitivity to atorvastatin is associated with increased accumulation of intracellular lipid droplets and fatty acid metabolism in breast cancer cells
Authors: Lettiero Barbara , Inasu Maria , Kimbung Siker , Borgquist Signe
Published: March 2018

Apart from the relevant lipid-lowering effects, statins have demonstrated significant, although heterogeneous, anti-tumor activities in preventing breast cancer (BC) progression. To characterize the critical pathways behind the diverse responses to therapy, we investigated statin-induced changes in regulation of lipid metabolism and abundance of neutral lipid-containing cytoplasmic lipid droplets (LDs) in BC cells displaying different sensitivity to atorvastatin. Following atorvastatin treatment, accumulated LD levels inversely mirrored the marginal anti-proliferative effects in a dose and time-dependent manner in the less-sensitive BC cells. Transcriptional profiling excluded dysregulation of lipid uptake and efflux as specific mechanisms associated with differences in LD accumulation and anti-proliferative effects of atorvastatin. Notably, significant upregulation of genes involved in unsaturated fatty acid metabolism [stearoyl-CoA desaturase (SCD)] and cholesterol biosynthesis [3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR)], were associated with atorvastatin insensitivity. Taken together, the increased ability to store neutral lipids in LDs as consequence of atorvastatin treatment likely confers a proliferative advantage to BC cells and may serve as potential biomarker of statin resistance in BC. Contributions of cholesterol biosynthesis and unsaturated fatty acid metabolism to LD formation should be thoroughly explored for better understanding of the molecular mechanisms underlying statin-induced effects against BC progression.
Synthesis of inverse ringwoodite sheds light on the subduction history of Tibetan ophiolites
Authors: Bindi Luca , Griffin William L. , Panero Wendy R. , Sirotkina Ekaterina , Bobrov Andrey , Irifune Tetsuo
Published: March 2018

Tibetan ophiolites are shallow mantle material and crustal slabs that were subducted as deep as the mantle transition zone, a conclusion supported by the discovery of high-pressure phases like inverse ringwoodite in these sequences. Ringwoodite, Mg2SiO4, exhibits the normal spinel structure, with Mg in the octahedral A site and Si in the tetrahedral B site. Through A and B site-disorder, the inverse spinel has four-coordinated A cations and the six-coordinated site hosts a mixture of A and B cations. This process affects the density and impedance contrasts across the boundaries in the transition zone and seismic-wave velocities in this portion of the Earth. We report the first synthesis at high pressure (20 GPa) and high temperature (1600 °C) of a Cr-bearing ringwoodite with a completely inverse-spinel structure. Chemical, structural, and computational analysis confirm the stability of inverse ringwoodite and add further constraints to the subduction history of the Luobusa peridotite of the Tibetan ophiolites.
mTORC1 impedes osteoclast differentiation via calcineurin and NFATc1
Authors: Huynh HoangDinh , Wan Yihong
Published: March 2018

Rapamycins are immunosuppressant and anti-cancer drugs that inhibit the kinase mTOR. Clinically, they often cause bone pain, bone necrosis, and high bone turnover, yet the mechanisms are unclear. Here we show that mTORC1 activity is high in osteoclast precursors but downregulated upon RANKL treatment. Loss-of-function genetic models reveal that while early Raptor deletion in hematopoietic stem cells blunts osteoclastogenesis due to compromised proliferation/survival, late Raptor deletion in osteoclast precursors instead augments osteoclastogenesis. Gain-of-function genetic models by TSC1 deletion in HSCs or osteoclast precursors cause constitutive mTORC1 activation, impairing osteoclastogenesis. Pharmacologically, rapamycin treatment at low but clinically relevant doses exacerbates osteoclast differentiation and bone resorption, leading to bone loss. Mechanistically, RANKL inactivates mTORC1 via calcineurin-mediated mTORC1 dephosphorylation, consequently activating NFATc1 by reducing mTORC1-mediated NFATc1 phosphorylation. These findings uncover biphasic roles of mTORC1 in osteoclastogenesis, dosage-dependent effects of rapamycin on bone, and a previously unrecognized calcineurin–mTORC1–NFATc1 phosphorylation-regulatory signaling cascade.
A phage display-based strategy for the de novo creation of disulfide-constrained and isomer-free bicyclic peptide affinity reagents
Authors: Zha Mirao , Lin Ping , Yao Hongwei , Zhao Yibing , Wu Chuanliu
Published: March 2018

We report a phage-screening strategy for the development of bicyclic peptide ligands constrained with two sterically different and isomerically forbidden noncanonical disulfide bridges without elaborate chemical modifications and recourses to genetic code reprogramming.
Rational construction of a 3D hierarchical NiCo2O4/PANI/MF composite foam as a high-performance electrode for asymmetric supercapacitors
Authors: Cui Fen , Huang Yunpeng , Xu Le , Zhao Yan , Lian Jiabiao , Bao Jian , Li Huaming
Published: March 2018

A 3D hierarchical NiCo2O4/PANI/MF composite foam with a macroporous 3D skeleton, a conductive PANI coating and electrochemically active NiCo2O4 delivers high electrochemical capacitance.
Emerging chemical strategies for imprinting magnetism in graphene and related 2D materials for spintronic and biomedical applications
Authors: Tuček Jiří , Błoński Piotr , Ugolotti Juri , Swain Akshaya Kumar , Enoki Toshiaki , Zbořil Radek
Published: March 2018

The review highlights recent theoretical and experimental advancements in imprinting and tuning magnetic properties in graphene and related 2D materials by various chemical approaches.
Recent advances in functionalized micro and mesoporous carbon materials: synthesis and applications
Authors: Benzigar Mercy R. , Talapaneni Siddulu Naidu , Joseph Stalin , Ramadass Kavitha , Singh Gurwinder , Scaranto Jessica , Ravon Ugo , Al-Bahily Khalid , Vinu Ajayan
Published: March 2018

This review provides the recent progress and advances in the design, synthesis and high throughput applications of functionalized micro and mesoporous carbon materials.
Intercalation of Bi nanoparticles into graphite results in an ultra-fast and ultra-stable anode material for sodium-ion batteries
Authors: Chen Ji , Fan Xiulin , Ji Xiao , Gao Tao , Hou Singyuk , Zhou Xiuquan , Wang Luning , Wang Fei , Yang Chongyin , Chen Long , Wang Chunsheng
Published: March 2018

Bi@Graphite was synthesized as an ultra-fast and ultra-stable anode material for SIBs with 70% capacity retention at 300C with respect to 1C.
Highly efficient photothermal sterilization of water mediated by Prussian blue nanocages
Authors: Jiang Tingting , He Jiaojie , Sun Lei , Wang Yuanlin , Li Zhenglin , Wang Qiao , Sun Ye , Wang Wei , Yu Miao
Published: March 2018

Photothermal sterilization based on PBNs has been demonstrated not only upon NIR irradiation but also most importantly under simulated solar light.
In vitro and environmental toxicity of reduced graphene oxide as an additive in automotive lubricants
Authors: Esquivel-Gaon Margarita , Nguyen Nhung H. A. , Sgroi Mauro F. , Pullini Daniele , Gili Flavia , Mangherini Davide , Pruna Alina Iuliana , Rosicka Petra , Sevcu Alena , Castagnola Valentina
Published: March 2018

A workflow for evaluation of human and environmental toxicity of nanosized bare graphene material intended as a motorcar lubricant nanoadditive.
Tuning ultrafast electron injection dynamics at organic-graphene/metal interfaces
Authors: Ravikumar Abhilash , Kladnik Gregor , Müller Moritz , Cossaro Albano , Bavdek Gregor , Patera Laerte L. , Sánchez-Portal Daniel , Venkataraman Latha , Morgante Alberto , Brivio Gian Paolo , Cvetko Dean , Fratesi Guido
Published: March 2018

We assess ultrafast charge transfer dynamics between molecules and epitaxial or bilayer graphene/Ni(111) interfaces by ab initio theory and X-ray spectroscopy.
Hierarchically porous, ultra-strong reduced graphene oxide-cellulose nanocrystal sponges for exceptional adsorption of water contaminants
Authors: Yousefi Nariman , Wong Kerwin K. W. , Hosseinidoust Zeinab , Sørensen Henning Osholm , Bruns Stefan , Zheng Yi , Tufenkji Nathalie
Published: March 2018

Self-assembly of graphene oxide (GO) nanosheets into strong and hierarchically porous 3D sponges is a promising approach to exploit their capacity to adsorb contaminants while facilitating the recovery of the nanosheets from treated water.
Pushing the limits of applicability of REBCO coated conductor films through fine chemical tuning and nanoengineering of inclusions
Authors: Rizzo F. , Augieri A. , Kursumovic A. , Bianchetti M. , Opherden L. , Sieger M. , Hühne R. , Hänisch J. , Meledin A. , Van Tendeloo G. , MacManus-Driscoll J. L. , Celentano G.
Published: March 2018

Tailoring of self-assembled nanoinclusions in the YBCO matrix improves in-temperature and in-field performances.
Packing of metalized polymer nanofibers for aneurysm embolization
Authors: Kim Min-Woo , An Seongpil , Kim Karam , Kim Tae-Gun , Jo Hong Seok , Park Dong-Hyuk , Yoon Sam S. , Yarin Alexander L.
Published: March 2018

Aneurysmal subarachnoid hemorrhage (SAH) is the extravasation of blood into the subarachnoid space and is fatal in most cases.
Cyclometalated gold(iii) complexes: noticeable differences between (N,C) and (P,C) ligands in migratory insertion
Authors: Serra Jordi , Font Pau , Sosa Carrizo E. Daiann , Mallet-Ladeira Sonia , Massou Stéphane , Parella Teodor , Miqueu Karinne , Amgoune Abderrahmane , Ribas Xavi , Bourissou Didier
Published: March 2018

Gold(iii) complexes are garnering increasing interest for opto-electronic, therapeutic and catalytic applications.
Towards a molecular understanding of cellulose dissolution in ionic liquids: anion/cation effect, synergistic mechanism and physicochemical aspects
Authors: Li Yao , Wang Jianji , Liu Xiaomin , Zhang Suojiang
Published: March 2018

This perspective summarizes mechanistic studies on cellulose dissolution in ionic liquids, highlighting the synergistic mechanism, physicochemical aspects and future research trends.
Capillary assembly as a tool for the heterogeneous integration of micro- and nanoscale objects
Authors: Ni Songbo , Isa Lucio , Wolf Heiko
Published: March 2018

Capillary assembly is a powerful method for the deposition of a broad range of colloidal objects with great flexibility regarding their composition and shape.
Metal–organic frameworks as affinity agents to enhance the microdialysis sampling efficiency of fatty acids
Authors: Yang Hui , Li Tuo , Liu Lu , Li Na , Guan Ming , Zhang Yangyang , Wang Zhenpeng , Zhao Zhenwen
Published: March 2018

MOFs as affinity agents were added into a perfusate to enhance the microdialysis sampling efficiency of fatty acids for the first time.
Selective trapping of CO2 gas and cage occupancy in CO2–N2 and CO2–CO mixed gas hydrates
Authors: Petuya Claire , Damay Françoise , Desplanche Sarah , Talaga David , Desmedt Arnaud
Published: March 2018

New carbon dioxide separation and capture technology, thanks to clathrate hydrate formation from pressurized ice with (carbon monoxide and nitrogen containing) gas mixtures.
Bright violet-to-aqua-emitting cadmium-free Ag-doped Zn–Ga–S quantum dots with high stability
Authors: Zhang Wen-Jin , Pan Chun-Yang , Cao Fan , Wang Haoran , Yang Xuyong
Published: March 2018

Herein, we report a new series of ultra-stable Cd-free Ag:Zn–Ga–S/ZnS quantum dots (QDs) with an overall short emission wavelength tunable from 370 to 540 nm via a facile one-pot non-injection method.
Making good on a promise: ionic liquids with genuinely high degrees of thermal stability
Authors: Rabideau Brooks D. , West Kevin N. , Davis James H.
Published: March 2018

Most ionic liquids are not, as frequently asserted, materials of unusual thermal stability. However, it is possible to create ionic liquids which are, through a combination of iterative ion design/synthesis, and thermochemical measurements, coupled with quantum and molecular dynamics calculations.
Copper-mediated regioselective C–H etherification of naphthylamides with arylboronic acids using water as an oxygen source
Authors: Roy Subhasish , Pradhan Sourav , Punniyamurthy Tharmalingam
Published: March 2018

Copper-mediated etherification of naphthylamides with arylboronic acid is presented. The H2O18 labelling experiment reveals the incorporation of the ether oxygen from water. The kinetic isotope study suggests that C–H activation is the rate determining step.
Lead-carboxylate/polyiodide hybrids constructed from halogen bonding and asymmetric viologen: structures, visible-light-driven photocatalytic properties and enhanced photocurrent responses
Authors: Zhao Li-Ming , Zhang Wen-Ting , Song Kai-Yue , Wu Qi-Qi , Li Yi , Li Hao-Hong , Chen Zhi-Rong
Published: March 2018

Two lead-carboxylate/polyiodide hybrids constructed from halogen bonding and asymmetric viologen have been synthesized, which exhibit efficient photocatalytic degeneration performances.
The impact of metal ions on photoinduced electron-transfer properties: four photochromic metal–organic frameworks based on a naphthalenediimide chromophore
Authors: Xu Hui-Ling , Zeng Xiao-Shan , Li Jie , Xu Yu-Ci , Qiu Hai-Jiang , Xiao Dong-Rong
Published: March 2018

Four photochromic MOFs show that electron-withdrawing capabilities of metal ions play a significant role in tuning the photosensitivity of photochromic MOFs.
Cellular uptake efficiency of nanoparticles investigated by three-dimensional imaging
Authors: Goh Yeongchang , Song Yo Han , Lee Gibok , Bae Hyeongyu , Mahata Manoj Kumar , Lee Kang Taek
Published: March 2018

Cellular uptake of upconversion nanoparticles is successfully demonstrated by a new, fast and background-free 3-D imaging technique.
Coexistence of distinct intramolecular electron transfer pathways in polyoxometalate based molecular triads
Authors: Luo Yusen , Wächtler Maria , Barthelmes Kevin , Winter Andreas , Schubert Ulrich S. , Dietzek Benjamin
Published: March 2018

Polyoxometalate (POM)-associated charge-separated states have attracted much attention due to the remarkable catalytic properties of the reduced POMs.
Ion pairing in 1-butyl-3-methylpyridinium halide ionic liquids studied using NMR and DFT calculations
Authors: Swamy Vincent P. , Thulasiram Hirekodathakallu V. , Rastrelli Federico , Saielli Giacomo
Published: March 2018

Experimental and calculated 1H, 13C and 15N NMR data of bulk 1-butyl-3-methylimidazolium halides ionic liquids provide key insights on their ion pairing.
Palladium islands on iron oxide nanoparticles for hydrodesulfurization catalysis
Authors: Mansouri Ali , Semagina Natalia
Published: March 2018

Deposition of thin Pd islands on iron oxide nanoparticles results in a 4-fold activity enhancement in HDS and suppresses cracking.
Direct cross-coupling between alkenes and tetrahydrofuran with a platinum-loaded titanium oxide photocatalyst
Authors: Tyagi Akanksha , Yamamoto Akira , Yamamoto Muneaki , Yoshida Tomoko , Yoshida Hisao
Published: March 2018

A Pt-loaded TiO2 photocatalyst successfully catalyzed the direct cross-coupling between various alkenes and tetrahydrofuran (THF) without any additional oxidizing agent.
Sr5Os3O13: a mixed valence osmium(v,vi) layered perovskite variant exhibiting temperature dependent charge distribution
Authors: Mohitkar Shrikant A. , Nuss Jürgen , Höppe Henning A. , Felser Claudia , Jansen Martin
Published: March 2018

New mixed-valent Sr5Os3O13 represents a particular cutout of the perovskite structure and features continuous charge ordering with temperature.
Sulfonated carbon-encapsulated iron nanoparticles as an efficient magnetic nanocatalyst for highly selective synthesis of benzimidazoles
Authors: Kasprzak Artur , Bystrzejewski Michał , Poplawska Magdalena
Published: March 2018

Various benzimidazoles were obtained by applying sulfonated carbon-encapsulated iron nanoparticles as the nanocatalyst.
The transformation behaviour of “alucones”, deposited by molecular layer deposition, in nanoporous Al2O3layers
Authors: Van de Kerckhove Kevin , Barr Maïssa K. S. , Santinacci Lionel , Vereecken Philippe M. , Dendooven Jolien , Detavernier Christophe
Published: March 2018

Wet and heat treatments of different alucones result in porous alumina with tuneable porosity and pore size.
Co3O4 nanowire@NiO nanosheet arrays for high performance asymmetric supercapacitors
Authors: Xing Lei , Dong Yidi , Hu Fang , Wu Xiang , Umar Ahmad
Published: March 2018

Herein, we report a simple and facile sequential hydrothermal process for the synthesis of Co3O4 nanowire@NiO nanosheet arrays (CNAs).
One-dimensional hierarchical MoO2–MoSxhybrids as highly active and durable catalysts in the hydrogen evolution reaction
Authors: Qiu Yu , Chai Liying , Su Yi , Li Ping , Yuan Wenyu , Li Hailong , Guo Xiaohui
Published: March 2018

A kind of 1D MoO2–MoSxhybrid structures was synthesizedviaa facilein-situsynthetic method. The obtained MoO2–MoSxcatalysts delivered high electrocatalytic activity and excellent cyclic durability in HER.
Biomimetic ion channels formation by emulsion based on chemically modified cyclodextrin nanotubes
Authors: Bacri Laurent , Mamad-Hemouch Hajar , Przybylski Cédric , Thiébot Bénédicte , Patriarche Gilles , Jarroux Nathalie , Pelta Juan
Published: March 2018

We present short cyclodextrin nanotubes that form ion channels in lipid bilayers.
The art in science of MicroTAS: 10 years of miniaturized art
Authors: Reyes Darwin R.
Published: March 2018

Maria Cristina Letizia (center) from EPFL, Switzerland, was the winner of the 2017 MicroTAS Art in Science competition. She received the award certificate from Maria Southall (right) from Lab on a Chip and Darwin Reyes (left) from NIST.
Understanding charge transfer and recombination by interface engineering for improving the efficiency of PbS quantum dot solar cells
Authors: Ding Chao , Zhang Yaohong , Liu Feng , Kitabatake Yukiko , Hayase Shuzi , Toyoda Taro , Wang Ruixiang , Yoshino Kenji , Minemoto Takashi , Shen Qing
Published: March 2018

In Mg-doped ZnO/PbS QDHSCs, a spike structure is formed between the QDs and the “electron acceptor”, which improved charge collection efficiency.
Complexes of phosphonate and phosphinate derivatives of dipicolylamine
Authors: Hlinová Veronika , Jaroš Adam , David Tomáš , Císařová Ivana , Kotek Jan , Kubíček Vojtěch , Hermann Petr
Published: March 2018

Phospho(i)nate derivatives of dipicolylamine show excellent selectivity for Zn(ii) over alkaline earth metal ions.
ZnxFe3−xO4 (0.01 ≤ x ≤ 0.8) nanoparticles for controlled magnetic hyperthermia application
Authors: Srivastava M. , Alla S. K. , Meena Sher Singh , Gupta Nidhi , Mandal R. K. , Prasad N. K.
Published: March 2018

Stable temperature was attained during magnetic hyperthermia by Zn substituted magnetite nanoparticles.
Facile one-pot hydrothermal synthesis of particle-based nitrogen-doped carbon spheres and their supercapacitor performance
Authors: Zhang Ang , Cao Shubo , Zhao Yongbin , Zhang Chen , Chen Aihua
Published: March 2018

Particle-based nitrogen-doped carbon spheres (PNCSs) were prepared via a hydrothermal and carbonization route and PNCSs-1.2 demonstrated an enhanced supercapacitor performance.
New strategy for the azido–ascorbic acid reaction: a convenient chemosensor and its imaging in garlic slice tissues
Authors: Zhang Dan , Li Na , Ma Yiming , Wang Ruixue , Wang Jinyi , Wang Junru
Published: March 2018

Three chemosensors with azide groups at different sites were designed for rapid detection of ascorbic acid in garlic slice tissues.
Confined metal Ge quantum dots in carbon nanofibers for stable rechargeable batteries
Authors: Wei Wei , Wang Hua , Tian Aihua , Wang Kefeng , Wang Junmei , Qu Peng , Zhang Shiying , Guo Lin
Published: March 2018

Ge quantum dots were uniformly confined in porous carbon nanofibers and this nanocomposite exhibits excellent Li storage performance.
Non-destructive characterization of extended crystalline defects in confined semiconductor device structures
Authors: Schulze Andreas , Strakos Libor , Vystavel Tomas , Loo Roger , Pacco Antoine , Collaert Nadine , Vandervorst Wilfried , Caymax Matty
Published: March 2018

Non-destructive and quantitative characterization of crystalline defects: understanding the formation and distribution of defects in nanoscale semiconductor device structures.
A facile method to functionalize gold nano-tripods with high suspension stability in an aqueous environment
Authors: Tang T.-Y. , Wang H.-L. , Yao C.-T. , Yang K.-C. , Ho R.-M. , Tsai D.-H.
Published: March 2018

A facile method for preparing and characterizing Au nano-tripods with high aqueous suspension stability.
Intra- and inter-nanocrystal charge transport in nanocrystal films
Authors: Aigner Willi , Bienek Oliver , Falcão Bruno P. , Ahmed Safwan U. , Wiggers Hartmut , Stutzmann Martin , Pereira Rui N.
Published: March 2018

The exploitation of semiconductor nanocrystal (NC) films in novel electronic and optoelectronic applications requires a better understanding of charge transport in these systems.
Ligand-mediated synthesis of compositionally related cesium lead halide CsPb2X5 nanowires with improved stability
Authors: Ruan Longfei , Lin Jin , Shen Wei , Deng Zhengtao
Published: March 2018

Compositionally related cesium lead halide materials, such as CsPb2X5, have attracted great interest due to their considerable optoelectronic/optical properties as well as improved stability.
Highly efficient hydroboration of carbonyl compounds catalyzed by tris(methylcyclopentadienyl)lanthanide complexes
Authors: Yan Dandan , Dai Ping , Chen Sufang , Xue Mingqiang , Yao Yingming , Shen Qi , Bao Xiaoguang
Published: March 2018

(MeCp)3Ln complexes are reported as highly efficient catalysts in promoting hydroboration and a plausible stepwise mechanism is proposed.
Ruthenium(ii)-catalyzed remote C–H addition of 8 aminoquinoline amide to activated aldehyde
Authors: Mondal Susmita , Hajra Alakananda
Published: March 2018

Remote C–H addition of 8-aminoquinoline amides at C-5 position to activated aldehydes have been developed using Ru(ii)-catalyst.
α-Methyl phenylglycines by asymmetric α-arylation of alanine and their effect on the conformational preference of helical Aib foldamers
Authors: Costil Romain , Fernández-Nieto Fernando , Atkinson Rachel C. , Clayden Jonathan
Published: March 2018

Asymmetric arylation of an alanine derivative provides (R)-α-methyl phenylglycine, which induces a right handed screw sense in an Aib oligomer.
Losing supramolecular orientational memory via self-organization of a misfolded secondary structure
Authors: Sahoo Dipankar , Peterca Mihai , Aqad Emad , Partridge Benjamin E. , Klein Michael L. , Percec Virgil
Published: March 2018

Comparing the self-organization of two dendronized perylene bisimides reveals how structurally defective primary structure eliminates memory function via hierarchical self-organization.
Stable copper acetylacetonate-based oxidizing agents in redox (NIR photoactivated) polymerization: an opportunity for the one pot grafting from approach and an example on a 3D printed object
Authors: Garra Patxi , Dumur Frédéric , Nechab Malek , Morlet-Savary Fabrice , Dietlin Céline , Graff Bernadette , Gigmes Didier , Fouassier Jean-Pierre , Lalevée Jacques
Published: March 2018

Stable Cu(ii) ox. agent for redox (graft) polymerization.
A 2D porous pentiptycene-based MOF for efficient detection of Ba2+ and selective adsorption of dyes from water
Authors: Zhang Minghui , Qi Ziqiang , Feng Yang , Guo Bingbing , Hao Yujian , Xu Zhuo , Zhang Liangliang , Sun Daofeng
Published: March 2018

The 2D MOF (UPC-28) as the water monitor can exhibit efficient detection of Ba2+ and perform selective adsorption of dyes from water.
Transition metal oxides for aqueous sodium-ion electrochemical energy storage
Authors: Boyd Shelby , Augustyn Veronica
Published: March 2018

This work illustrates the obstacles that must be overcome and the benefits offered by aqueous rechargeable Na+electrochemical energy storage.
Enhanced 5D0 → 7F4 transition and optical thermometry of garnet type Ca3Ga2Ge3O12:Eu3+ phosphors
Authors: Chi Fengfeng , Wei Xiantao , Zhou Shaoshuai , Chen Yonghu , Duan Changkui , Yin Min
Published: March 2018

Emission spectra of Ca3Ga2Ge3O12:Eu3+ phosphors at room temperature (a) and the temperature range of 160–360 K (b).
Photo-induced, Cu-catalyzed three component azidofluoroalkylation of alkenes with CF3I and RfI as fluoroalkylation reagents
Authors: Liu Hong , Guo Quanping , Chen Chao , Wang Mengran , Xu Zhaoqing
Published: March 2018

Under UV light irradiation, the Cu-catalyzed azidofluoroalkylation of alkenes was realized by directly using fluoroalkyl iodides as fluoroalkylation reagents.
Experimental measurements of the permeability characteristics of rare earth ore under the hydro-chemical coupling effect
Authors: Wang Xiaojun , Zhuo Yulong , Zhao Kui , Zhong Wen
Published: March 2018

Two coupling processes—solution seepage and chemical replacement—occur in the in situ leaching process of ion-absorbed-rare-earth ore.
Fatigue endurance enhancement of Sn-doped Pb(Lu1/2Nb1/2)O3–PbTiO3 ceramics
Authors: Wang Chenxi , He Chao , Wang Zujian , Li Xiuzhi , Yang Xiaoming , Liu Ying , Long Xifa
Published: March 2018

Fatigue endurance has been enhanced of Sn-doped Pb(Lu1/2Nb1/2)O3–PbTiO3 ceramics, exhibiting an abnormal self-rejuvenation of remnant polarization.
Mesoporous TiO2coating on carbon–sulfur cathode for high capacity Li–sulfur battery
Authors: Dharmasena Ruchira , Thapa Arjun Kumar , Hona Ram Krishna , Jasinski Jacek , Sunkara Mahendra K. , Sumanasekera Gamini U.
Published: March 2018

Mesoporous TiO2coating on carbon–sulfur cathode with simple electrical contact for high capacity Li–S battery.
Experiments indicating a second hydrogen ordered phase of ice VI
Authors: Gasser Tobias M. , Thoeny Alexander V. , Plaga Lucie J. , Köster Karsten W. , Etter Martin , Böhmer Roland , Loerting Thomas
Published: March 2018

We report on the discovery and characterization of ice β-XV, which represents the second hydrogen ordered polymorph related to ice VI.
Molecular mechanism of lytic polysaccharide monooxygenases
Authors: Hedegård Erik Donovan , Ryde Ulf
Published: March 2018

The lytic polysaccharide monooxygenases (LPMOs) are copper metalloenzymes that can enhance polysaccharide depolymerization through an oxidative mechanism and hence boost generation of biofuel from e.g. cellulose. By employing density functional theory in a combination of quantum mechanics and molecular mechanics (QM/MM), we report a complete description of the molecular mechanism of LPMOs.
Identification of Pt-based catalysts for propane dehydrogenation via a probability analysis
Authors: Zha Shenjun , Sun Guodong , Wu Tengfang , Zhao Jiubing , Zhao Zhi-Jian , Gong Jinlong
Published: March 2018

A probability-based computational screening study has successfully identified an optimal bimetallic alloy (Pt3In) for the propane dehydrogenation reaction.
Vapor-deposited organic glasses exhibit enhanced stability against photodegradation
Authors: Qiu Yue , Dalal Shakeel S. , Ediger M. D.
Published: March 2018

This work shows the first demonstration that amorphous packing arrangements can significantly modulate photodegradation in organic glasses.
Generation of 3-dimensional multi-patches on silica particles via printing with wrinkled stamps
Authors: John D. , Zimmermann M. , Böker A.
Published: March 2018

A simple route towards patchy particles with adjustable numbers as well as distances between patches is presented.
Nitrogen-rich hollow carbon spheres decorated with FeCo/fluorine-rich carbon for high performance symmetric supercapacitors
Authors: Karuppannan Mohanraju , Kim Youngkwang , Sung Yung-Eun , Kwon Oh Joong
Published: March 2018

A novel investigation was performed on fluorine-rich carbon shell formation on metal (Fe/Co/FeCo) surfaces and their contribution to capacitance enhancement was evaluated.
A high-performance SDC-infiltrated nanoporous silver cathode with superior thermal stability for low temperature solid oxide fuel cells
Authors: Lee Tsung-Han , Fan Liangdong , Yu Chen-Chiang , Wiria Florencia Edith , Su Pei-Chen
Published: March 2018

A simple and effective infiltration method is demonstrated to improve the thermal stability and electrochemical performance of a nanoporous silver cathode.
Stannate derived bimetallic nanoparticles for electrocatalytic CO2 reduction
Authors: Zhang Xiaolong , Li Fengwang , Zhang Ying , Bond Alan M. , Zhang Jie
Published: March 2018

Stannate derived bimetallic systems can achieve highly efficient electrocatalytic CO2 reduction to formate.
CLPFFD–PEG functionalized NIR-absorbing hollow gold nanospheres and gold nanorods inhibit β-amyloid aggregation
Authors: Ruff J. , Hassan N. , Morales-Zavala F. , Steitz J. , Araya E. , Kogan M. J. , Simon U.
Published: March 2018

Gold nanoparticles with specific optical properties in combination with the CLPFFD peptide that exhibits selectivity for β-amyloid (Aβ) aggregates are promising photothermal absorbers for application in Alzheimer's disease therapy.
The Complexity Approach to Phonological Treatment: How to Select Treatment Targets
Authors: Storkel Holly L.
Published: March 2018

Purpose

There are a number of evidence-based treatments for preschool children with phonological disorders (Baker & McLeod, 2011). However, a recent survey by Brumbaugh and Smit (2013) suggests that speech-language pathologists are not equally familiar with all evidence-based treatment alternatives, particularly the complexity approach. The goal of this clinical tutorial is to provide coaching on the implementation of the complexity approach in clinical practice, focusing on treatment target selection.

Method

Evidence related to selecting targets for treatment based on characteristics of the targets (i.e., developmental norms, implicational universals) and characteristics of children's knowledge of the targets (i.e., accuracy, stimulability) is reviewed. Free resources are provided to aid clinicians in assessing accuracy and stimulability of singletons and clusters. Use of treatment target selection and generalization prediction worksheets is illustrated with 3 preschool children.

Results

Clinicians can integrate multiple pieces of information to select complex targets and successfully apply the complexity approach to their own clinical practice.

Conclusion

Incorporating the complexity approach into clinical practice will expand the range of evidence-based treatment options that clinicians can use when treating preschool children with phonological disorders.

Supplemental Material S1

https://doi.org/10.23641/asha.6007562

KU ScholarWorks Supplemental Material

http://hdl.handle.net/1808/24767
Stellar populations of HII galaxies
Authors: Telles Eduardo , Melnick Jorge
Published: March 2018

Aims. We present a UV to mid-IR spectral energy distribution (SED) study of a large sample of SDSS DR13 HII galaxies. These galaxies are selected as starbursts (EW(Hα) > 50Å) and for their high-excitation locus in the upper left region of the BPT diagram. Their photometry was derived from the cross-matched GALEX, SDSS, UKDISS, and WISE catalogs.

Methods. We used CIGALE modeling and a SED fitting routine with the parametrization of a three-burst star formation history, and a comprehensive analysis of all other model parameters. We were able to estimate the contribution of the underlying old stellar population to the observed equivalent width of Hβ, and allow for more accurate burst age determination.

Results. We found that the star formation histories of HII Galaxies can be reproduced remarkably well by three major eras of star formation. In addition, the SED fitting results indicate that in all cases the current burst produces a small percent of the total stellar mass, i.e., the bulk of stellar mass in HII galaxies has been produced by the past episodes of star formation, and also indicate that at a given age the Hβ luminosity depends only on the mass of young stars favoring a universal IMF for massive stars. Most importantly, the current star formation episodes are maximum starbursts that produce stars at the highest possible rate.
Formation of close-in super-Earths in evolving protoplanetary disks due to disk winds
Authors: Ogihara Masahiro , Kokubo Eiichiro , Suzuki Takeru K. , Morbidelli Alessandro
Published: March 2018

Context. Planets with masses larger than about 0.1 M⊕ undergo rapid inward migration (type I migration) in a standard protoplanetary disk. Recent magnetohydrodynamical simulations revealed the presence of magnetically driven disk winds, which would alter the disk profile and the type I migration in the close-in region.

Aims. We investigate orbital evolution of planetary embryos in disks that viscously evolve under the effects of disk winds. The aim is to discuss effects of altered disk profiles on type I migration. In addition, we aim to examine whether observed distributions of close-in super-Earths can be reproduced by simulations that include effects of disk winds.

Methods. We perform N-body simulations of super-Earth formation from planetary embryos, in which a recent model for disk evolution is used. We explore a wide range of parameters and draw general trends. We also carry out N-body simulations of close-in super-Earth formation from embryos in such disks under various conditions.

Results. We find that the type I migration is significantly suppressed in many cases. Even in cases in which inward migration occurs, the migration timescale is lengthened to 1 Myr, which mitigates the type I migration problem. This is because the gas surface density is decreased and has a flatter profile in the close-in region due to disk winds. We find that when the type I migration is significantly suppressed, planets undergo late orbital instability during the gas depletion, leading to a non-resonant configuration. We also find that observed distributions of close-in super-Earths (e.g., period ratio, mass ratio) can be reproduced. In addition, we show that in some results of simulations, systems with a chain of resonant planets, like the TRAPPIST-1 system, form.
Investment Management of Agro-Ecological Farms
Authors: Borisova Victoria , Samoshkina Iryna
Published: March 2018

The effective development of farms requires the environmental and economic investing, which provides for investments in improving the soil quality that can be enhanced through a fresh look at the problem of degradation, given that agricultural land is considered to be produced, not primary resource, similar to all other kinds of resources accounted in agriculture. The degradation and restoration of land productivity are the problems of the analysis of investment updates, modified with the aim of establishing the relationship of the soil quality and relevant investments. The effective investing of additional capital is crucial for the successful investment activities of agro-ecological farms, while investment resources are subject to management. The stirring up of investment activities is possible on the basis of the environmental and economic planning of farms as the important link in the structure of the organizational and economic mechanism of farm operation, the efficient investment management. The article focuses on the directions of attracting investments in agro-ecological farms and agricultural enterprises to improve their business performance. The investment attractiveness of environmental agribusiness is justified. The features of management and trends in the development of the investment activities of agro-ecological farms are identified.