bluuebunny/crossref_metadata_2025 huggingface dataset:
Patterns and prognosis of holding regimens for people living with HIV in Asian countries
Authors: Kim Jung Ho , Jiamsakul Awachana , Kiertiburanakul Sasisopin , Huy Bui Vu , Khusuwan Suwimon , Kumarasamy Nagalingeswaran , Ng Oon Tek , Ly Penh Sun , Lee Man-Po , Chan Yu-Jiun , Gani Yasmin Mohamed , Azwa Iskandar , Avihingsanon Anchalee , Merati Tuti Parwati , Pujari Sanjay , Chaiwarith Romanee , Zhang Fujie , Tanuma Junko , Do Cuong Duy , Ditangco Rossana , Yunihastuti Evy , Ross Jeremy , Choi Jun Yong ,   on behalf of IeDEA Asia-Pacific
Published: March 2022

The use of holding regimens for people living with HIV (PLWH) without effective antiretroviral options can have effects on outcomes and future treatment options. We aimed to investigate the use of holding regimens for PLWH in Asian countries. Data from adults enrolled in routine HIV care in IeDEA Asia-Pacific cohorts were included. Individuals were considered to be on holding regimen if they had been on combination antiretroviral therapy for at least 6 months, had two confirmed viral loads (VL) ≥1000 copies/mL, and had remained on the same medications for at least 6 months. Survival time was analyzed using Fine and Gray’s competing risk regression. Factors associated with CD4 changes and VL <1000 copies/mL were analyzed using linear regression and logistic regression, respectively. A total of 425 PLWH (72.9% male; 45.2% high-income and 54.8% low-to-middle-income country) met criteria for being on a holding regimen. From high-income countries, 63.0% were on protease inhibitors (PIs); from low-to-middle-income countries, 58.4% were on non-nucleoside reverse transcriptase inhibitors (NNRTIs); overall, 4.5% were on integrase inhibitors. The combination of lamivudine, zidovudine, and efavirenz was the most commonly used single regimen (n = 46, 10.8%), followed by lamivudine, zidovudine, and nevirapine (n = 37, 8.7%). Forty-one PLWH (9.7%) died during follow-up (mortality rate 2.0 per 100 person-years). Age >50 years compared to age 31–40 years (sub-hazard ratio [SHR] 3.29, 95% CI 1.45–7.43, p = 0.004), and VL ≥1000 copies/ml compared to VL <1000 copies/mL (SHR, 2.14, 95% CI 1.08–4.25, p = 0.029) were associated with increased mortality, while higher CD4 counts were protective. In our Asia regional cohort, there was a diversity of holding regimens, and the patterns of PI vs. NNRTI use differed by country income levels. Considering the high mortality rate of PLWH with holding regimen, efforts to extend accessibility to additional antiretroviral options are needed in our region.
Influence of the COVID-19 pandemic on running behaviors, motives, and running-related injury: A one-year follow-up survey
Authors: DeJong Lempke Alexandra F. , Hertel Jay
Published: March 2022

The purpose of this study was to compare running behaviors, motives, and injury during the first full year of the pandemic compared to the year prior, and month of eased restrictions. 466 runners responded to this follow-up survey. Paired t-tests were used to compare timepoints. Logistic regressions were used to assess demographic influences on behaviors. During the first full year of the pandemic, runners were more likely to increase their weekly runs (Mean Differences [MD]: 0.29±0.10, p < .001), yet had fewer motives (MD: -0.20±0.06, p = .02) compared to the month of eased restrictions. 18–25-year-olds were most likely to increase running volume (Odds Ratio [OR]: 2.79 [1.06, 7.32], p = .04) during the first full year of the pandemic compared to the year prior. Inexperienced runners reported fewer motives (OR: 3.00–4.41, p = .02-.04), and reduced sustained runs (OR: 2.36 [1.13, 4.96], p = .02) during the first full year of the pandemic compared to the year prior. Inexperienced runners and runners who lost access to preferred locations were at increased injury risk (OR: 1.98–2.63, p: .01-.04) during the first full year of the pandemic compared to the year prior. Our findings highlight pandemic-related changes among the running community that are likely to influence behaviors and injury risk.
Communication about vaccine efficacy and COVID-19 vaccine choice: Evidence from a survey experiment in the United States
Authors: Kreps Sarah , Kriner Douglas L.
Published: March 2022

While mass vaccination campaigns against COVID-19 have inoculated almost 200 million Americans and billions more worldwide, significant pockets of vaccine hesitancy remain. Research has firmly established that vaccine efficacy is an important driver of public vaccine acceptance and choice. However, current vaccines offer widely varying levels of protection against different adverse health outcomes of COVID-19. This study employs an experiment embedded on a survey of 1,194 US adults in June 2021 to examine how communications about vaccine efficacy affect vaccine choice. The experiment manipulated how vaccine efficacy was defined across four treatments: (1) protection against symptomatic infection; (2) protection against severe illness; (3) protection against hospitalization/death; (4) efficacy data on all three metrics. The control group received no efficacy information. Subjects were asked to choose between a pair of vaccines—a one-dose viral vector vaccine or two-dose mRNA vaccine—whose efficacy data varied across the four experimental treatment groups. Efficacy data for each vaccine on each dimension were adapted from clinical trial data on the Johnson & Johnson/Janssen and Pfizer/BioNTech vaccines. Among all respondents, only modest preference gaps between the two vaccines emerged in the control group and when the two vaccines’ roughly equivalent efficacy data against hospitalization and death were reported. Strong preferences for a two-dose mRNA vaccine emerged in treatments where its higher efficacy against symptomatic or severe illness was reported, as well as in the treatment where data on all three efficacy criteria were reported. Unvaccinated respondents preferred a one-dose viral vector vaccine when only efficacy data against hospitalization or death was presented. Black and Latino respondents were significantly more likely to choose the one-shot viral vector vaccine in the combined efficacy treatment than were whites. Results speak to the importance of understanding how communications about vaccine efficacy affect public preferences in an era of increasing uncertainty about efficacy against variants.
Odour enhances the sense of presence in a virtual reality environment
Authors: Archer Nicholas S. , Bluff Andrew , Eddy Andrew , Nikhil Chreshall K. , Hazell Nick , Frank Damian , Johnston Andrew
Published: March 2022

Virtual reality (VR) headsets provide immersive audio-visual experiences for users, but usually neglect to provide olfactory cues that can provide additional information about our environment in the real world. This paper examines whether the introduction of smells into the VR environment enhances users’ experience, including their sense of presence through collection of both psychological and physiological measures. Using precise odour administration with an olfactometer, study participants were exposed to smells while they were immersed in the popular PlayStation VR game “Resident Evil 7”. A within-subject study design was undertaken where participants (n = 22) walked-through the same VR environment twice, with or without the introduction of associated congruent odour stimuli. Directly after each gameplay, participants completed a questionnaire to determine their sense of presence from the overall gameplay and their sense of immersion in each of the virtual scenes. Additionally, physiological measurements (heart rate, body temperature and skin electrodermal activity) were collected from participants (n = 11) for each gameplay. The results showed the addition of odours significantly increased participants’ sense of spatial presence in the VR environment compared to VR with no odour. Participants also rated the realism of VR experience with odour higher compared to no odour, however odour addition did not result in change in emotional state of participants (arousal, pleasure, dominance). Further, the participants’ physiological responses were impacted by the addition of odour. Odour mediated physiological changes were dependent on whether the VR environment was novel, as the effect of odour on physiological response was lost when participants experienced the aroma on the second gameplay. Overall, the results indicate the addition of odours to a VR environment had a significant effect on both the psychological and physiological experience showing the addition of smell enhanced the VR environment. The incorporation of odours to VR environments presents an opportunity to create a more immersive experience to increase a person’s presence within a VR environment. In addition to gaming, the results have broader applications for virtual training environments and virtual reality exposure therapy.
Oral, genital and anal human papillomavirus infections among female sex workers in Ibadan, Nigeria
Authors: Morhason-Bello Imran O. , Baisley Kathy , Pavon Miquel A. , Adewole Isaac F. , Bakare Rasheed A. , de Sanjosé Silvia , Francis Suzanna C. , Watson-Jones Deborah
Published: March 2022

Background

There are limited data on the epidemiology of HPV in different anatomical sites of female sex workers (FSW). We investigated the prevalence and concordance of cervical, vulval, oral and anal HPV among FSW in Ibadan, Nigeria.

Methods

FSWs aged 18–45 years were enrolled in a cross-sectional survey. After interview and clinical examination, samples were collected from mouth, cervix, vulva and anus. HPV genotyping was done with Anyplex II 28HPV assay. Multivariable analyses were performed to explore associated risk factors and concordance of HPV infections across sites.

Results

In total, 315 FSWs participated in the study with a mean age of 30–6.5 years. The prevalence of any HPV infection was 88% in the vulva, 84% in the cervix, 75% in the anus and 24% in the oral cavity. HPV 35 was the most prevalent and concordant high-risk type in the four sites. The risk factors for HPV infection by anatomic site varied.

Conclusion

This large study showed a high prevalence and concordance of HPV infections of cervical, vulval, oral and anal HPV among FSWs in Nigeria. The potential to acquire and transmit HPV is high in this population, and we highlighted the urgency to protect young women through HPV vaccination.
De los tipos ideales a las realidades históricas. El fascismo italiano a la luz de la teoría ideacional del populismo
Authors: Llamazares Iván , Ramos-González Jorge
Published: March 2022

El fascismo ha sido escasamente analizado por la literatura académica centrada en el populismo. Los estudios que han combinado el interés por ambos fenómenos han adolecido bien de una escasa base teórica (en el caso de los estudios prioritariamente centrados en el fascismo), bien de una gran inconcreción empírica (en el caso de los estudios que partían de algún marco teórico sobre el populismo). En el presente trabajo intentamos superar estos dos tipos de limitaciones realizando un análisis del discurso fascista italiano a partir de la teoría ideacional, tomando este discurso tal y como aparece en los textos de su líder y fundador, Benito Mussolini. Nuestro análisis identifica los componentes populistas básicos del discurso fascista italiano y muestra también la existencia de algunos patrones generales que caracterizan a la retórica populista en distintas coyunturas históricas. Además, el análisis nos proporciona algunas perspectivas útiles para interpretar las características de actores políticos contemporáneos vinculados, directa o indirectamente, al fascismo. En último término, nuestro análisis muestra que los estudios históricos siguen resultando cruciales para testar y refinar las teorías desarrolladas por la ciencia política contemporánea.
Diagnostic and Prognostic Values of KRAS Mutations on EUS-FNA Specimens and Circulating Tumor DNA in Patients With Pancreatic Cancer
Authors: Wang Ronghua , Zhao Yuchong , Wang Yun , Zhao Zhenxiong , Chen Qian , Duan Yaqi , Xiong Si , Luan Zhou , Wang Jinlin , Cheng Bin
Published: March 2022

INTRODUCTION:

The ability of carbohydrate antigen 19-9 (CA19-9) to differentiate pancreatic cancer from other benign pancreatic lesions is unsatisfactory. This study explored the diagnostic value of KRAS gene mutations and plasma circulating tumor DNA (ctDNA) in patients with pancreatic cancer.

METHODS:

The prospective cohort study comprised 149 consecutive patients with solid pancreatic lesions who underwent endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA). KRAS subtype mutations were analyzed by digital droplet PCR (ddPCR) in EUS-FNA histopathology tissue samples, and blood samples were sent for plasma ctDNA analysis. The final diagnosis was based on surgical resection pathology or follow-up for at least 2 years.

RESULTS:

Adding KRAS mutation ddPCR increased the sensitivity and accuracy of EUS-FNA from 71.4% to 91.6% (P < 0.001) and 75.8% to 88.6% (P < 0.001), respectively. By comparison, the sensitivities of circulating biomarkers ctDNA and CA19-9 were only 35.2% and 71.2%. The area under the curve of the receiver operating characteristic curve (AUC) of EUS-FNA and KRAS ddPCR combination was >0.90 for distinguishing pancreatic cancer from benign lesions, whereas the AUC of EUS-FNA and CA19-9 combination was 0.83. The median survival time was significantly shorter in patients with G12D KRAS mutations than that in patients with other mutations (180 vs 240 days, P < 0.001).

DISCUSSION:

FNA tissue sample KRAS mutation analysis in tissues significantly improves the diagnostic accuracy of cyto/histopathological evaluation in EUS-FNA samples. The combination of EUS-FNA and tissue sample KRAS ddPCR provided a more accurate method for pancreatic cancer diagnosis, superior to the combination of EUS-FNA and CA19-9/ctDNA. G12D KRAS mutations in pancreatic cancer were independently associated with poor overall survival.
Radiation Monitoring in the Residential Environment: Time Dependencies of Air Dose Rate and 137Cs Inventory
Authors: Yoshimura Kazuya , Nakama Shigeo , Fujiwara Kenso
Published: March 2022

Background: Residential areas have some factors on the external exposure of residents, who usually spend a long time in these areas. Although various survey has been carried out by the government or the research institutions after the Fukushima Daiichi Nuclear Power Plant accident, the mechanism of radiocesium inventory in the terrestrial zone has not been cleared. To better evaluate the radiation environment, this study investigated the temporal changes in air dose rate and 137Cs inventories (Bq/m2) in residential areas and agricultural fields.Materials and Methods: Air dose rate and 137Cs inventories were investigated in residential areas located in an evacuation zone at 5–8 km from the Fukushima Daiichi Nuclear Power Plant. From December 2014 to September 2018, the air dose rate distribution was investigated through a walking survey (backpack survey), which was conducted by operators carrying a γ-ray detector on their backs. Additionally, from December 2014 to January 2021, the 137Cs inventories on paved and permeable grounds were also measured using a portable γ-ray detector.Results and Discussion: In the areas where decontamination was not performed, the air dose rate decreased faster in residential areas than in agricultural fields. Moreover, the 137Cs inventory on paved surfaces decreased with time owing to the horizontal wash-off, while the 137Cs inventory on permeable surfaces decreased dramatically owing to the decontamination activities.Conclusion: These findings suggest that the horizontal wash-off of 137Cs on paved surfaces facilitated the air dose rate decrease in residential areas to a greater extent compared with agricultural fields, in which the air dose rate decreased because of the vertical migration of 137Cs. Results of this study can explain the faster environmental restoration in a residential environment reported by previous studies.
Student Experiences on Emergency Synchronous Online Teaching in Higher Education
Authors: Acar Ciftci Yasemin
Published: March 2022

This research aims to reveal university students’ experiences, expectations, and suggestions regarding synchronous online teaching. For this purpose, the study was conducted in a qualitative research case study design. The study group of the research consists of 24 university students. The research data were collected using a semi-structured interview form and document review technique. The data obtained through the semi-structured interview form were analysed using the descriptive analysis technique through the MAXQDA qualitative data analysis program. Research findings show that students have problems accessing devices and the internet. Students and instructors are not competent in using technology and do not have pedagogical content knowledge. The findings reveal that students do not open their webcams and are unwilling to attend and participate in classes because the strategies used in the learning-teaching process are not suitable for classroom interaction. Additionally, students could easily cheat in online exams and had some problems about self-regulation skills. In line with these findings, it has been proposed self-regulated learning framework, formative and authentic assessments and the “community of inquiry” framework.
The Cheating Heart: Phenomenology in Women Who Decides to Have an Affair in Marriage
Authors: Shaleha Rinanda Rizky Amalia
Published: March 2022

Infidelity in marriage is a complex process. People have different reasons for deciding to have a relationship outside of marriage. This study aims to investigate the reasons of married women for having marital infidelity and explore the risk factors that cause it. This research was conducted using a qualitative approach with phenomenology as the method. Three women who have had marital infidelity are willing to be subjects in this study. Data was collected by using open interview and observation methods. As a result, failed conflict resolution, different communication styles, low-quality time, low intimacy, unfulfilled expectations from partners, and the absence of protective factors are factors that cause women to have an affair.
The Role of Peer Rejection in Adolescent Internalizing Problems
Authors: Syakarofath Nandy Agustin , Biorohmi Ananda Nabilah , Latipun Latipun
Published: March 2022

Emotional distress, such as symptoms of anxiety, depression, and withdrawal, is on the rise among teenagers today. These symptoms are generally grouped into internalizing problems. Based on research, a risk factor that contributes to internalizing problems is peer rejection. This study aims to determine the effect of peer rejection on adolescent internalizing problems. Research design is quantitative research with a multistage random sampling technique as a data collection technique. The subjects of this study were 252 adolescents aged 16-18 years who are currently studying in SMA in Bondowoso Regency, consisting of 103 boys (M = 40.068; SD = 13.283) and 149 girls (M = 40.893; SD =13.283). The instruments used were Social Peer Rejection Measure (21 items, α = .90) and Strengths and Difficulty Questionnaire (SDQ), just for internalizing problems (10 items, α = .72). The results of the analysis test using simple linear regression showed that there was a positive influence of peer rejection on internalizing problems in high school adolescents in Bondowoso Regency, adjusted R 2 = .278; F(4, 427) = 251, p = .000). This influence shows that the more often adolescents experience rejection from their peers, the higher the chances of experiencing internalizing problems.
Oczekiwania i doświadczenia wsparcia rodziców dzieci z niepełnosprawnością
Authors: Buchnat Marzena
Published: March 2022

Most parents of children with disabilities still do not know what support they can expect in the situation in which they have found themselves, and where and to whom they can turn for such support. Knowledge on this subject by medical, educational and local government employees is non-complex and does not create a coherent system, and therefore does not meet the expectations and needs of the parents. Assessment of the support obtained by individual groups, as well as access to suport systems and legal, financial and psychological assistance in the rehabilitation of a child in the organization of free time, is very diverse, which proves the ineffective functioning of information on such support and assistance systems. The aim of the conducted research was to what support was given to parents of children with disabilities and whether it is relevant to their needs and expectations. The research used a quantitative and qualitative strategy. The research used the method of diagnostic survey was used, in which a questionnaire and a focus group interview were conducted. The results show that according to the parents of children with disabilities still do not receive adequate support in Poland in the situation in which they have found themselves. A coherent system should be created for the management of an integrated package of services to support families raising a child (children) with disabilities. This system, based on medical, educational and territorial employees, should provide comprehensive and effective access to information about the forms of support and assistance available to such families.
Parenting an Autistic Child Is Not Associated With the Amount of Facial Emotion Information Needed to Perceive Happiness or Sadness From Faces
Authors: Lampi Andrew J. , Jaswal Vikram K.
Published: March 2022

One common feature of autism is “flat affect:” Many autistic people do not facially express emotion as intensely as non-autistic people. Although it can be difficult for a casual acquaintance or stranger to infer what someone with flat affect is feeling, some mothers of autistic children report learning to identify their children’s emotions from limited facial emotion information. We investigated whether this parenting experience is associated with the point at which mothers perceive happiness and sadness on faces of individuals other than their children. We used two tasks where faces of strangers morphed from a neutral expression to peak happiness and peak sadness; we measured the point at which mothers first perceived happiness and sadness in these morphs. In samples that were overwhelmingly North American, White, and highly educated, mothers of autistic children (n = 24), mothers of non-autistic children (n = 24) and age-matched non-mothers (n = 24) did not differ in the point at which they perceived happiness and sadness. The heightened sensitivity some mothers of autistic children report in perceiving emotion on their children’s faces may not play a role in how they perceive emotion on other people’s faces, at least in the case of happiness and sadness. Interestingly, however, the three groups of middle-aged women perceived happiness (but not sadness) at an earlier point than a group of young adult women attending a U.S. university (n = 151), a finding that is consistent with socio-emotional selectivity theory.
Novi prinosi Bokanićima u Trogiru
Authors: Babić Ivo
Published: March 2022

Radionici bračkih kamenara iz roda Bokanić pripisuje se više građevinskih zahvata u Trogiru: preinaka crkve Svih svetih, gradnja portala i zvonika nekadašnje samostanske crkve Sv. Mihovila, grbovi i reljefi na kuli, na zgradi mlinova zvanoj Mlinice. Analizira se posebno arhitektonska leksika trećeg kata zvonika katedrale za čije je projektiranje prvotno bio angažiran proto Anzolo iz Venecije.
Stambene palače kasnog 18. stoljeća u Rijeci
Authors: Puhmajer Petar
Published: March 2022

U ovom radu obrađuje se korpus reprezentativne stambene arhitekture Rijeke s kraja 18. i samog početka 19. stoljeća koji je velikim dijelom danas gotovo iščeznuo. Uz nekoliko poznatih građevina, ovom se prigodom neke prvi put identificiraju, utvrđuju se njihovi vlasnici te vrijeme izgradnje. Nastanak palača povezuje se s proširenjem grada i rušenjem gradskih zidina unutar kojih izostaje reprezentativna izgradnja, a tek s formiranjem blokova Novog grada omogućeno je podizanje većih i kvalitetnijih kuća za stanovanje. Središnja zona postaje Korzo, duž i oko kojega palače podižu imućni trgovci, brodovlasnici i činovnici. Prostorna organizacija palača razmatra se većinom na temelju arhivske dokumentacije iz vremena kada je još bila sačuvana, ili se barem mogla iščitati, a uočava se nekoliko karakterističnih prostornih obrazaca čiji se koncepti povezuju s položajem i nastankom u gradskom bloku te tipskim modelima iz regije. Pročelja kao relevantni parametar u definiranju građevina kao palača pokazuju znatnu uniformnost, ali i razlike, osobito oblikovanjem zabatnih zaključaka koja im daju vizualni identitet i reprezentativnost, a slijedom kojih se mogu odrediti njihova tipološka obilježja.
Damage to the Environment Arising From Pesticides: An Evaluation From The International Literature
Authors:   Nilva Lúcia Rech Stédile, Rech da Rosa Artur
Published: March 2022

Abstract: This paper aims to make an integrative review of the literature on scientific papers of an international database on the subject of pesticides, identifying those related to the degradation of the environment, analyzing its main objectives, results, year of publication and place of study. A period of 18 years, periodicals of levels A1 and A2 of free access were used, with Digital Object Identifier System and that they fit in the area of Engineering I of the Commission of Improvement of Personnel of the Superior Level. Afterwards, the abstracts were analyzed and classified by central object of study, producing figures and comparative tables for the interpretation of the data. Only 10 articles were found that fit the inclusion criteria, being 80% of exploratory research, 7 of the 10 papers were published after 2010, showing a growth of production from one decade to another of 234%, the focus is on water, with 50% of the papers and were carried out mainly in developed countries, corresponding to 70% of the publications. The results showed that exposure to the substances was higher than allowed by the countries where the analyzes were performed and that there were several adverse effects from exposure. Key words: pesticides, agrochemical, environment, environmental quality
Factors Influencing Dementia-Screening Behaviors of Community-Dwelling Adults Using the Korean Community Health Survey in 2018
Authors: Kim Sun-Hee , Lee Hyeonju , Son Youn-Jung , Kim Da-Young
Published: March 2022

Background: This study aimed to identify factors influencing dementia-screening behaviors among community-dwelling middle-aged and older adults using the Korean Community Health Survey data in 2018.Methods: This cross-sectional study included community-dwelling adults aged ≥50 years. We used data related to socio-demographic and health-related factors and subjective cognitive function. We conducted a chi-squared test and multiple logistic regression analysis with weighted analysis.Results: Of 108,050 participants (men, 46.6%; ≥65 years old, 41.5%), only 13.4% (20,404 participants) performed dementia-screening. Using multiple logistic regression, we found that advanced age, female, and unemployed, having a low level of education, low monthly family income, and rural residence, no alcohol intake, no-smoking, hypertension, cognitive dysfunction, and awareness of the dementia helpline service center were positively associated with dementia-screening behaviors.Conclusions: This study suggests the application of holistic approaches to improve dementia-screening behaviors among middle-aged and older adults considering their socioeconomic and health related conditions. Our findings highlight that government health programs should consider socio-economic status and awareness of dementia helpline services in designing dementia prevention programs.
Business Performance Evaluation Practice in Manufacturing Sector in Latvia
Authors: Kotane Inta , Mietule Iveta
Published: March 2022

The manufacturing sector plays an important role in promoting Latvia’s economic growth; this sector is one of the largest sectors of the Latvian economy. Performance can be described as one of the most important categories of economic analysis; however, there is no consensus among researchers on the business performance indicators, their measurement and evaluation methods. The research is based on the analysis of special literature and scientific publications, the evaluation of the financial ratios used in the financial analysis of companies by Latvian institutions, the results of an expert survey, and data from the Official Statistics Portal of Latvia. Literature analysis, expert surveys, correlations, multiple linear regression and forecasting methods were used in the research. The aim of the research is to identify and summarize the performance evaluation practices of manufacturing companies in Latvia. As a result of the research, the business performance evaluation practice in the manufacturing sector was analyzed, the significance of the financial ratios used in the financial analysis in the business performance evaluation in the manufacturing sector and the existence of statistically significant correlations between the financial analysis indicators of manufacturing companies and the key business indicators of manufacturing companies were identified and evaluated.
The Image of Lithuanian Public Prosecutors and Prosecutorial Offices
Authors: Valickas Gintautas , Vanagaitė Kristina
Published: March 2022

The article examines the character, similarities and differences of the image (or its separate components) of public prosecutors and prosecutorial offices perceived by the prosecutors (n = 322), police officers (n = 113), attorneys (n = 85), judges (n = 103) and the general public representing different age groups (n = 623), as well as the relations among the image of prosecutors and prosecutorial offices, experience accumulated by participants, and sociodemographic characteristics.
Short-term effects of fibrinolytic therapy on the hemodynamic parameters of patients with intermediate- and high-risk pulmonary embolism
Authors: Çıldır Hamza , Aksay Ersin , Şancı Emre , Bayram Başak , Çolak Neşe , Sevinç Can
Published: March 2022

Objective We aimed to determine the effect of fibrinolytic therapy on hemodynamic parameters at 4 hours after treatment and bleeding complications in patients with intermediate- and high-risk pulmonary embolism.Methods This single-center, retrospective, cohort study included patients with intermediate- and high-risk pulmonary embolism treated with fibrinolytics. Their demographic and clinical characteristics, complications, and vital signs at the initiation of and 4 hours after fibrinolytic therapy were evaluated. The primary outcome was the change in the patients’ vital signs at 4 hours after fibrinolytic therapy, compared by the Mann-Whitney U-test.Results Seventy-nine patients were included in this study. The systolic and diastolic blood pressures of the high-risk group at 4 hours after fibrinolytic therapy were higher than those at the initiation of fibrinolytic therapy (80 mmHg vs. 99 mmHg, P = 0.029; 49 mmHg vs. 67 mmHg, P = 0.011, respectively). In the intermediate-risk group, the oxygen saturation increased (94% vs. 96%, P = 0.004) and pulse rate decreased (104 beats/min vs. 91 beats/min, P < 0.001).Conclusion Blood pressure at 4 hours after fibrinolytic therapy increased in patients with high-risk pulmonary embolism. Also, oxygen saturation and pulse rate improved in intermediate-risk patients.
Stock de activos intangibles y rentabilidad empresarial. El caso de la industria hotelera española (2008-2019)
Authors: Ramón-Dangla Remedios , Bañón Calatrava Cristina
Published: March 2022

La literatura es prolija intentando establecer relaciones entre innovación y resultado empresarial, pero la diversidad de conclusiones procedentes de la definición o medición de la innovación motivó la elaboración de este trabajo. Nuestro objetivo fue comprobar si el stock de activos intangibles de las empresas hoteleras españolas mantiene una relación significativa con la rentabilidad (roa) y si esta es distinta dependiendo del tamaño y la edad. La importancia económica de la industria hotelera y su necesidad de mantener la competitividad internacional explican su elección. Como marco teórico, tomamos el enfoque basado en los recursos y capacidades de la empresa (ebr), porque resalta los recursos internos intangibles como clave para mantener las ventajas competitivas entre empresas del mismo sector. Así, construimos un panel de datos (2008-2019) y analizamos los activos intangibles de las 1.927 empresas hoteleras extraídos de la base de datos Sistema de Análisis de Balances Ibéricos (sabi). Construimos un índice de innovación (ii) de cada empresa y año, y buscamos su relación con la roa por tamaño y edad. Nuestros resultados revelaron que el ii estaba positivamente correlacionado con la roa, sobre todo para los hoteles más antiguos y de tamaño mediano-grande, pero los hoteles de tamaño muy grande tenían una relación significativa y negativa: conforme crecen las empresas, crece la innovación, pero solo hasta un límite.
Será a dinâmica Ichimoku eficiente? Uma evidência nos mercados de ações
Authors: Gomes Almeida Luís António
Published: March 2022

este artigo visa contribuir para o aumento do conhecimento do método de negociação Ichimoku, através de evidências teórico-empíricas sobre a capacidade preditiva dessa dinâmica de investimento. Apesar de essa dinâmica de investimento ter aparecido no Japão na década de 1930, só nos últimos anos começou a ganhar relevância para os investidores e académicos fora do Japão, existindo ainda uma lacuna na existência de trabalhos de investigação académica. Na persecução desse objetivo, estudaram-se cinco índices de mercados de capitais de diferentes zonas geográficas, tendo sido analisadas 26.295 cotações diárias, testando-se diferentes estratégias de negociação baseadas nas linhas Ichimoku. As estratégias de negociação produziram um conjunto de 22.083 sinais de negociação, possibilitando avaliar a capacidade preditiva e performance do sistema de negociação Ichimoku. O trabalho permitiu concluir que a dinâmica de negociação Ichimoku fornece sinais de tendências de negociação, sendo que as estratégias implementadas permitem criar valor para os investidores. Conclui-se também que a dinâmica Ichimoku apoia as decisões de investimento e possibilita que os investidores reajam rapidamente no mercado bearish, sendo útil para sinalizar tendências e revertê-las. A estratégia baseada na linha chikou span mostrou ser a mais rentável e a que propicia melhor remuneração por acréscimo de risco.
Las condiciones explicativas de la lealtad del cliente en las relaciones comerciales B2B
Authors: Granados-Payán Juan Carlos , Pedraza-Rodríguez José Antonio , Pérez Leonor M. , Gallarza Martina G.
Published: March 2022

El estudio del binomio rentabilidad-lealtad del cliente suscita el interés de académicos y empresarios por la influencia que tiene sobre el valor del cliente, la sostenibilidad y el crecimiento de la empresa. Este artículo explora el concepto de valor y la cadena de efectos del valor percibido, la satisfacción y otros vínculos intermedios como la confianza y el compromiso que conducen a la lealtad del cliente. Se utiliza el análisis cualitativo comparado (qca, por sus siglas en inglés) para estudiar esta cadena de efectos difíciles de observar debido a la ausencia de fuentes estandarizadas. El artículo realiza contribuciones de carácter metodológico para incrementar el grado de lealtad en los clientes. El análisis muestra los condicionantes que influyen en las relaciones comerciales B2B conducentes a la obtención de clientes leales. Las conclusiones resaltan las posibilidades de combinaciones “ganadoras” en la cadena de efectos para que las empresas evalúen su utilidad en la interacción con sus clientes cuando aplica estrategias para incrementar su lealtad en el proceso de compra. La aproximación cualitativa más útil evidencia la importancia de la satisfacción del cliente, enlazada con la confianza y el compromiso para captar y mantener a los clientes leales.
Visibilidade dos dados nos portais de dados governamentais abertos da América Latina
Authors: Conradi Barni Gabriel de Andrade , Moro Matheus Fernando , Bornia Antonio Cezar , Tezza Rafael
Published: March 2022

em portais de dados governamentais abertos (dga), não basta reunir uma grande quantidade de dados para alcançar transparência, engajamento, inovação e crescimento econômico. É preciso oferecer mecanismos para que o usuário encontre e utilize os dados, o que é conhecido como “visibilidade” em dga. Com o objetivo de avaliar a visibilidade dos portais de dga dos governos federais dos países da América Latina, tomou-se visibilidade como uma variável composta por 14 critérios desenvolvidos com base em uma revisão bibliográfica. A análise constatou que os portais precisam, principalmente, desenvolver recursos para serem visualizados em outro idioma, disponibilizar um campo de busca interativo e relacionar diferentes dados com conjuntos específicos. O portal do governo federal da Colômbia e do Paraguai se mostraram os de melhor desempenho, pois cumpriram com 11 critérios analisados.
Análisis de las condiciones laborales de la jefatura de familia en México: precariedad compartida, necesidades diferenciadas
Authors: Salas Durazo Iván Alejandro , Soria Romo Rigoberto , Rivas Jiménez Claudia Patricia
Published: March 2022

En el presente escrito se caracterizaron y contrastaron las condiciones laborales de mujeres y hombres jefes de familia mediante una tipología que consideró escolaridad, edad, tipo de empleo y estado civil. Con los grupos más representativos se analizaron las principales características laborales con la finalidad de valorar su precariedad laboral. Se empleó la metodología de análisis cualitativo comparado mediante la generación de tablas de verdad utilizando los microdatos de la Encuesta Nacional de Ocupación y Empleo al primer trimestre de 2019. Como resultados, se identificó una precariedad generalizada en las y los jefes de familia explicada por los bajos niveles de escolaridad, en contraste con las necesidades que suponen los roles de género. Asimismo, se identificaron tres grupos de jefas de familia: i) trabajos por cuenta propia, salarios bajos y nulo acceso a prestaciones; ii) trabajos subordinados con brechas de género adversas, y iii) trabajos subordinados con bajos niveles de precariedad. Una implicación de este escalonamiento está en la superposición de la ocupación con la etapa reproductiva y de crianza. Cabe destacar que este trabajo se centró únicamente en las condiciones laborales, dejando de lado aspectos de la dinámica familiar.
Eficacia de herbicidas preemergentes en el control de Oryza latifolia Desv. (arroz pato)
Authors: Picado-Arroyo Grettel , Herrera-Murillo Franklin
Published: March 2022

Introducción. Oryza latifolia es una especie silvestre en plantaciones de arroz comercial, su control es difícil dada la poca disponibilidad de herbicidas eficaces y selectivos al arroz cultivado. Objetivo. Identificar herbicidas preemergentes para controlar O. latifolia y estimar el tiempo de espera para sembrar arroz comercial. Materiales y métodos. De abril a octubre del 2019 se realizaron dos experimentos en la Estación Experimental Agrícola Fabio Baudrit Moreno, Alajuela, Costa Rica. Se utilizaron macetas plásticas de 3 L de capacidad, llenas con suelo arcilloso. En cada maceta se sembraron treinta semillas de O. latifolia. En el primer experimento se evaluó el oxifluorfen (480, 720 y 960 g i.a. ha-1), oxadiargil (300, 400 y 500 g i.a. ha-1), pretilaclor (1000, 1500 y 2000 g i.a. ha-1), atrazina (1500, 2000 y 2500 g i.a. ha-1), acetoclor (1500, 2000 y 2500 g i.a. ha-1) y un testigo sin herbicida. En el segundo experimento se evaluaron el oxifluorfen (480 g i.a. ha-1) y la atrazina (2000 g i.a. ha-1) aplicados a las 0, 1, 2, 3 y 4 semanas antes de sembrar la variedad de arroz Palmar 18. En ambos experimentos se utilizó un diseño irrestricto al azar con cinco repeticiones. Se evaluó el control y biomasa aérea seca de O. latifolia y la variedad Palmar 18. Resultados. El oxifluorfen en las dosis evaluadas mostró la mayor eficacia con 100 % de control de O. latifolia, seguido de la atrazina a 2000 g i.a. ha-1 con 80 %; sin embargo, ambos herbicidas causaron daños de leves a moderados en la variedad de arroz cuando se aplicaron entre 0 y 4 semanas antes de la siembra. Conclusión. El oxifluorfen fue el herbicida preemergente más eficaz para el control de O. latifolia, pero no se determinó con exactitud el tiempo de espera para sembrar la variedad Palmar 18.
Effect of donkey milk lactoferrin and lysozyme on yoghurt properties
Authors:   Ankara University, Faculty of Agriculture, Department of Dairy Technology, Turkey, Ceren Akal H.
Published: March 2022

Food industry has mostly focused on natural preservatives due to the undesirable effects of chemical additives on the human health. Among milk proteins, lactoferrin and lysozyme are the best-known for their antimicrobial. In this study, lactoferrin and lysozyme were extracted from donkey milk and applied on the yoghurt surface by spraying. The obtained yoghurt samples enriched with antimicrobial proteins were compared with the control sample produced without the addition of any preservatives as well as the samples treated with natamycin, a commercial preservative used in dairy products. Thereby physicochemical, microbiological and textural properties of the samples were investigated during the 30 days of storage. Yoghurt samples treated with antimicrobial agents had lower microbial load than control samples, which indicated that the donkey milk lactoferrin and lysozyme inhibit microbial activity in yoghurts. However, the addition of the mentioned preservatives did not change the gross composition and the textural properties of the yoghurt samples. Most importantly, the incorporation of lactoferrin or lysozyme did not adversely affect the sensory properties of yoghurt samples, but achieved higher appreciation points than the control sample on the 30th day of storage. In brief, lactoferrin and lysozyme extracted from donkey milk could be used to control the undesirable microbial growth, hence extending the shelf life of yoghurt.
Utilization of microalgae in probiotic white brined cheese
Authors:   Bursa Uludag University, Institute of Natural Sciences, Department of Food Engineering, Bursa, Turkey, Suna Gizem
Published: March 2022

In this study, the effects of Chlorella vulgaris and Arthrospira platensis fortification on the microbiological, physicochemical and antioxidative properties of probiotic white cheese during storage were investigated. Thereby six groups of white cheese samples were manufactured as follows WC (Control), LAC (Lactobacillus acidophilus LA-5), CWC (C. vulgaris), SWC (A. platensis), CLAC (C. vulgaris + Lb. acidophilus LA-5) and SLAC (A. platensis + Lb. acidophilus LA-5). The viability of Lb. acidophilus for SLAC sample remained almost constant during storage (>7 log cfu/g) while physicochemical properties of samples showed significant differences (P<0.01). The CLAC sample contained increased levels of protein, Ca, P, K, Mg and Zn while the highest Fe values were detected in the SLAC sample. Samples fortified with microalgae showed higher 1,1-diphenyl-2-picrylhydrazyl (DPPH)radical scavenging activity, cupric ion reducing antioxidant capacity (CUPRAC) and total phenolic content. Consequently, fortification with both microalgae improved the viability of probiotic, nutritional and antioxidative attributes of white cheese.
Modern aspects of cervical insufficiency etiology and pathogenesis
Authors:   Bogomolets National Medical University, Kyiv, Ukraine, Benyuk V.O. , Korniets N.G. ,   SE Lugansk State Medical University, Rubizhne, Ukraine, Oleshko V.F. ,   Bogomolets National Medical University, Kyiv, Ukraine,
Published: March 2022

The article deals with modern approaches to the etiology and pathogenesis of miscarriage in extremely early preterm labor. After all, newborns from such births are characterized by deep morphological and functional immaturity and form indicators of perinatal morbidity and mortality. The causes of miscarriage are varied and numerous. Cervical Insufficiency (CI) plays an important in the pathogenesis of premature birth, which is the result of the failure of the circular muscles of the internal orifice, isthmus and cervix. The existing types of CI are anatomical, functional and congenital. CI is a multifactorial complication of pregnancy. Genetic, hormonal, inflammatory-infectious, immunological, traumatic factors play a role in its development. A special role among the risk factors is played by Undifferentiated Connective Tissue Dysplasia, which is the result of violations of its development with defects of the main substance and fibers. The mechanisms of etiology and pathogenesis of asymptomatic cervical opening in preterm pregnancy are considered by analyzing the changes of hormonal and nutritive homeostasis, the state of collagen metabolism in Undifferentiated Connective Tissue Dysplasia. Key words: cervical insufficiency, extremely early premature birth, undifferentiated connective tissue dysplasia, hormonal imbalance, collagen metabolism disorder, nutritive disorders
Peculiarities of ultrasonic diagnostics in intrauterine growth retardation (IUGR)
Authors:   Danylo Halytskyy Lviv National Medical University, Ukraine, Markin L.B. , Matvienko O.O. ,   Danylo Halytskyy Lviv National Medical University, Ukraine
Published: March 2022

The article is dedicated to the peculiarities of ultrasonic diagnosis in intrauterine growth retardation (IUGR). Information on epidemiology, etiology and sonographic markers of this pathological condition is presented. Key words: intrauterine growth retardation, ultrasonic diagnostics.
Auxiliary (surrogate) motherhood as a medical and social problem
Authors:   Shupyk National Medical Academy of Postgraduate Education, Kуiv, Ukraine, Berestovoy O.O.
Published: March 2022

The problem of infertility is widespread all over the world, therefore, with the aim of solving it, the doctors developed the newest methods of treatment – assisted reproductive technologies (ART), among which the actual and widespread phenomenon of modernity is surrogate motherhood. According to this method, a woman, on the basis of mutual agreement with persons applying to her for providing this service, undergoes the procedure of implantation of an embryo created as a result of ART, nurtures a child in order to give birth and transfer it to these persons who will be legally considered the parents of this child. Ukraine is included in the category of countries where surrogate motherhood is allowed at the legislative level, but new legal relations generate new issues and a number of problems related to the realization of the right to motherhood and paternity. Key words: infertility, assisted reproductive technologies, assisted (surrogate) motherhood.