bluuebunny/crossref_metadata_2025 huggingface dataset:
Structural Characteristics of Drug Intercalated Hydrotalcites Used in Dental Medicine
Authors: Zegan Georgeta , Cernei Eduard Radu , Carausu Elena Mihaela , Golovcencu Loredana , Anistoroaei Daniela
Published: January 2020

Metronidazole active molecules were intercalated in the inner space of MgAl layered double hydroxides by simple coprecipitation method. The new synthesized nanohybrid material and the pristine hydrotalcite were characterized by different techniques such as X-ray diffraction, infrared spectroscopy and UV-vis spectroscopy verifying thus the incorporation of the antibiotic into the lamellar gallery of hydrotalcite type anionic clay. Studies regarding metronidazole controlled release from synthetic nanocomposite showed that the organic-inorganic nanohybrid structure can serve as drug controlled release system for a wide variety of antibiotics and other molecules used in dental medicine in order to maintain good public health dentistry.
Factors Influencing the Evolution of Pulmonary Hypertension in Patients with Hyperthyroidism
Authors: Tudoran Cristina , Tudoran Mariana , Parv Florina , Pop Gheorghe Nicusor , Awwad Ahmed Abu , Vlad Mihaela , Balas Melania
Published: January 2020

The aim of this study is to document the impact of thyroid hormones on pulmonary hypertension (PH). In two groups of hyperthyroid patients, one with Graves� disease and other with non-autoimmune aetiology, we have determined, by means of echocardiography, the estimated systolic pulmonary artery pressure (PAPs). We have documented an increased incidence of PH and statistically significant correlations between PAPs levels and free thyroxine (FT4), thyroid stimulating hormone (TSH) and TSH receptor antibodies (TRAb) and with the duration of hyperthyroidism. The severity of PH correlates with the severity and duration of hyperthyroidism. PAPs levels declined gradually, under specific therapy.
The European Baseline Series in Romania: Results of Patch Testing in Contact Dermatitis and Determination of the Most Frequently Awareness in Adult Patients
Authors: Constantin Maria-Magdalena , Bucur Stefana , Matei Clara , Nita Iuliana Elena , Constantin Traian
Published: January 2020

In Romania, data on patch testing are lacking and the significance and applicability of the European baseline series (EBS) needs to be evaluated. The aim of the study was to examine the prevalence of contact allergy to the EBS and to determine the most common post-test sensitization occurred in the population of patients with suspected allergic contact dermatitis in Romania. Demographic data were collected from 252 patients with suspected allergic contact dermatitis. Pacients were patch tested with 28-allergen EBS.The positive patch test was observed in 80.16% patients. The most prevalent contact allergens were nickel sulphate (15.08%), fragrance mix I & II (13.10%) and potassium dichromate (9.52%). Differences in sensitization prevalences to some allergens of the EBS compared with other European countries were recognized. The current EBS is a suitable diagnostic tool for contact allergy in Romania.
Current Guidance for Postextractional Hemmoragic Prophylaxis and Treatment
Authors: Budacu Cristian Constantin , Raftu Gheorghe , Debita Mihaela , Ciurcanu Oana , Mihai Constantin
Published: January 2020

Post-operative bleeding is a topical issue in dental practice, fact reflected by the etiopathogenic, morpho pathological and therapeutic aspects; may occur at any time as a complication of dental extraction, due to local factors or general factors. The peculiarity of the dental extraction complication lies in the fact that the physician must immediately resort to firm measures leading to its solving in the shortest while, the most prolonged bleeding can put the patient�s life at risk. Therefore surgery must be justified and applied only when the noticing methods are not effective.Knowing the pathology of the patient and its medication are of major importance in order to prevent post-operative hemorrhage complications. Dental extraction is the most frequent intervention of oral surgery that is addressed to both the dentist and the dento-alveolar surgeon, and is performed almost daily in the surgery.One of the local complications of dental extraction is post-surgical hemorrhage. Establishing a therapeutic, prophylactic and curative plan for this complication by conducting a good history of the patient accompanied by paraclinical examinations, the use of a well-established surgical technique can prevent post- operative hemorrhagic complications. The statistical survey was conducted between 2015 -2017; performed on a group of 225 patients. Knowing the methods of prophylaxis and treatment for post-operative bleeding, as well as the correct diagnosis of its causes are mandatory for every practitioner. Post-operative hemorrhage is a complication that can be prevented by making a correct and complete anamnesis, having as its etiology local causes (the most common) or general causes.
Quantification of the Impact on the Environment of Romanian National Airlines
Authors: Pietreanu Casandra Venera , Zaharia Sorin Eugen , Dinu Cornel
Published: January 2020

Air quality is submitted to national and international standards and regulations, thus air traffic growth�s implications on the environment can be analyzed only in compliance with such norms. While achieving the requirements of environmental protection reflected by legal frameworks, airlines have to establish their own responsibility policy based on emission reduction options, which can be approached by market strategies and technological developments. In this context, the paper aims at analyzing this long-term challenge for the Romanian aeronautical industry and assesses airlines� strategies and targets. The research also aims to quantify the impact on the environment of domestic flights performed by two national airlines (i.e. Tarom and Blue Air) on a peak period in terms of air traffic, with accent on the emissions of and(which represents a linear function of fuel burn).
In Vitro Testing of Salicylanilide Derivatives Against Some Fungal and Bacterial Strains
Authors: Ienascu Ioana Maria Carmen , Obistioiu Diana , Popescu Iuliana Maria , Stefanut Mariana Nela , Gyongyi Osser , Jurca Claudia , Ciavoi Gabriela , Bechir Edwin Sever , Bechir Farah , Cata Adina
Published: January 2020

In the dental office, disinfection and sterilization are a matter of utmost importance for both the physician, the medical staff and the patient. Twelve N-(2-bromo-phenyl)-2-hydroxy-benzamide and N-(4-bromo-phenyl)-2-hydroxy-benzamide derivatives were synthesized and tested for antimicrobial activity against 6 bacterial and 2 fungal strains using the Disk diffusion method for susceptibility testing. The obtained results indicated that the N-(2-bromo-phenyl)-2-hydroxy-benzamide derivatives were more active against the tested microbes, inhibition zones of 6-12 mm being obtained, although the most effective compound against S. pyogenes proved to be N-(4-bromo-phenyl)-2-hydroxy-benzamide (14 mm inhibition zone). The tested compounds presented no effect against S. aureus, S. flexneri, S. typhimurium and C. parapsilopsis at the tested concentration.
Quantum Biological Thermodynamics with Finite Speed of the Cardio-Pulmonary SystemI- Fundamental concepts, equations and diagrams
Authors: Petrescu Stoian , Borcila Bogdan , Costea Monica , Petrescu Valeria , Bolohan Romi
Published: January 2020

The paper presents the Fundamental Concepts, Equations and Diagrams in a new domain which is the extension of Thermodynamics with Finite Speed (TFS), invented and called by us: Quantum Biological Thermodynamics with Finite Speed of the Cardio-Pulmonary System (QBTFSCPS). The new concepts are: Stationary States, parameters of Stationary States, Processes between Stationary States with or without Quantum Jump, Non-Stationary States. Essential parameters of the Stationary States are: Frequency of Heart Oscillations FH, Frequency of Lungs Oscillations FL and Quantum Number N - which characterize the Synergetic (ordered) Interaction between Heart and Lungs, in a Stationary State. We present also a Fundamental Equation discovered by us, based on experimental data, which describes any Stationary States and 4 Equations of the Processes between these States in the Cardio-Pulmonary System. Based on these new concepts and new equations we invented 6 Diagrams which describe graphically in synoptic images the Stationary States and Processes between them with or Without Quantum Jump, between Quantum levels represented by the Quantum Number N (an integer number = 0, 1, 2, 3, 4, 5, 6, � etc.).
Conceptual Replication of Canine Serum Oxytocin Increase Following a Positive Dog-human Interaction
Authors: Hritcu Luminita Diana , Horhogea Cristina , Ciobica Alin , Spataru Mihaela Claudia , Spataru Constatin , Kis Anna
Published: January 2020

The neurohormone oxytocin is known to exert a special function in the regulation of social relationships throughout vertebrate taxa. Recently it has been discovered that not only within-species, but in certain cases, between-species social bonds are also mediated by the same hormone, e.g. in case of the dog�human relationship. However, despite the exponential growth of findings at the behavioural level, there are still a lot of controversies on the biochemical assessment of oxytocin in canine samples. Thus, in the current study we replicate previous findings of canine serum oxytocin increase following a positive dog�human interaction. We provide a detailed description of both the immunoassay method used as well as the behavioural protocol (including crucial time-parameters). This will serve as a base for further studies that both our group as well as others in the field will conduct.
Study Regarding the Imaging and Functional Evaluation in the Rehabilitation of Balance in Patients with Ischaemic Stroke
Authors: Lucaci Paul , Neculaes Marius , Haba Danisia
Published: January 2020

The present study is based on the paraclinical and functional evaluation of a sample of 66 subjects with ischaemic stroke, to monitor the evolution of their functional parameters. The tests concerning the variation of barycentre speed within the support polygon and the curve length were conducted using the GPS 400 Posturograph, which provided us with information related to the balance of the subjects in an orthostatic stance with eyes open, with eyes closed, looking to the right, looking to the left, head tilted to the right, head tilted to the left, head in extension. Our findings highlight the balance re-education capacity of the subjects with ischaemic stroke through individualised physical therapy programs.
Rapid Chemical Tests in the Autopsy Room
Authors: Hanganu Bianca , Hlescu Andreea Alexandra , Manoilescu Irina Smaranda , Birlescu Andreea Elena , Ciudin Valentin Petre , Dimitriu Cristina , Buhas Camelia Liana , Somlea Mihaela Cristina , Ioan Beatrice Gabriela
Published: January 2020

From its beginning, the autopsy represented a useful instrument for the progression of medicine and continues to be a valuable tool in postmortem diagnosis of various diseases or traumatic injuries. Modern laboratory technology is an important aid in achieving autopsy goals but it is either not available or not permanently available in all the departments of Forensic Medicine and do not offer every time quick results, which might be necessary to guide the next steps of the forensic investigation. In this paper the authors present a set of rapid, sensitive and effective chemical reactions, described in the literature over the time and meant to support the forensic experts, as they can be easily performed in the autopsy room. Moreover, the application of these reactions may reduce the costs of laboratory analyzes in cases where the use of expensive laboratory technologies is no longer required or limited by the results of these reactions. Also, a brief description of the collection method for biological samples to be used is provided. At the end of the paper the authors suggest a minimum kit of chemical substances which are necessary in the autopsy room, in order for these analyses to be performed.
Dysgerminoma - A Case Presentation
Authors: Tomescu Aneta , Mocanu Liliana , Brezeanu Dragos , Stanciu Gabriela , Sirbu Rodica , Tomescu Cezar
Published: January 2020

Dysgerminomas are a type of ovarian tumour which are developed from the germinal tissue and have a frequency of approximately 2% of all ovarian cancers. We report a case of a 40 years old female, which was admitted with abdominal pain and pollakiuria installed approximately 2 months ago. The particularity of the case lies in the late onset of the disease, compared to epidemiologic data, as well as in the immunohistochemical reactions, especially the negative PLAP reaction and positive CD30 reaction.
The Correlation between Specific Biochemical Parameters, Radiological data and clinical sings for practicing laparoscopic cholecystectomy in the first 24 hours for acute cholecystitis. How safe it is?
Authors: Brebu Dan Alin , Vlad Cristian , Tarta Cristi , Dobrescu Amadeus , Mihail Iuliana , Nica Cristian , Fulger Lazar , Duta Ciprian
Published: January 2020

The best timing of cholecystectomy on patients with acute gallbladder pathology is still unclearly defined. Some studies have reported that cholecystectomy during the index acute admission presents an increased morbidity rate, extended duration of stay and increased costs. The study below is aiming at finding the most accurate moment to practice the surgery when acute cholecystitis is confirmed. Consequently, 368 patients admitted to hospital from January 2013 to December 2015 with the diagnosis of acute cholecystitis (AC) who underwent cholecystectomy in the 2nd Department of Surgery, Emergency County Hospital, Timi�oara, Romania constituted the two lots. The cases were retrospectively identified, introduced into the database and the data were subsequently analyzed according to various parameters. The study results reveal that laparoscopic cholecystectomy (LC) in the first 24 hours is safe procedure on the majority of the cases. Also, our findings sustain that emergency cholecystectomy can reduce the length of hospital stay, having similar rates of conversion to open surgery, complications and outcome compared with a delayed operation.
NAP Neuroprotective Peptide and its Analogs: Simultaneously Copper and Iron Binding and Reduction
Authors: Lupaescu Ancuta-Veronica , Sandu Ion , Petre Brindusa Alina , Ion Laura , Ciobanu Catalina-Ionica , Drochioiu Gabi
Published: January 2020

Neurodegenerative diseases, including Alzheimer disease, involve mechanisms such as protein aggregation, free radical generation and oxidative stress. Transition metals such as copper and iron were linked to neurodegenerative pathology. Their pathogenic role consists in generating different reactive oxygen species and damaging tissues or cells through the Fenton reaction. Abnormal metabolism of copper and iron can lead to several chronic pathogenesis. NAP is a small active fragment of activity-dependent neuroprotective protein essential for brain formation. NAP peptide showed neuroprotective proprieties against toxicity induced by the �-amyloid peptide, N-methyl-D-aspartate, electrical blockade, the envelope protein of the AIDS virus, dopamine, H2O2, and nutrient starvation in cell culture. Therefore, we investigated here the interaction of Cu2+ and Fe3+ ions with the NAP neuroprotective peptide and its analogs. With MALDI-ToF mass spectrometry, the formation of reduced metal-peptide complexes and the metal chelating properties of NAP-like neuroprotective peptides were highlighted.
Research Concerning the Optimization of the Mechanism of the Conventional Sucker Rod Pumping Units
Authors: Toma Georgeta
Published: January 2020

Finding optimal solutions to design the mechanism of the conventional sucker rod pumping units is always present due to many problems that involve. The study in this case involves both the cinematic and dynamic analysis of the mechanism of the conventional pumping units, making sure that the optimization solution maintain unchanged certain operating parameters of the pumping equipment such as the stroke of the sucker rod column. In the paper is presented a method of determining the optimal dimensions of the structural elements of the mechanism of the conventional pumping units in order to reduce the maximum values of the connection forces in the bearings in the conditions of maintaining unchanged the stroke of the sucker rod column. The simulations have been performed in the case of a C-640D-305-120 pumping unit.
Multimodality Approach to Treatment of Rhinosinusal Tumours
Authors: Palade Octavian Dragos , Anghelina Florin , Dabija Marius Gabriel , Hainarosie Razvan , Domuta Eugenia Maria , Hinganu Delia , Hinganu Marius Valeriu , Radeanu Doinel
Published: January 2020

The treatmentdecision for rhinosinusal tumours requires accurate knowledge of the therapeutic principles specific to each histological type and tumoral extension. Therapy strategies have been developed based on the pathophysiological knowledge and the history of these tumors. Postoperative assessment remains necessary, to establish patient-specific oncological management. The purpose of this study is the retrospective analysis of cases with rhinosinusalmalignancies, diagnosed and treated in the Otolaryngology Unit of the Spiridon Emergency Clinical Hospital in Iasi. We evaluated the characteristics of the patient group using a statistical analysis that highlights the therapeutical modalities used in multimodal treatment, surgical techniques, chemotherapy, radiotherapy, and the therapeutic protocols, all of these beeing adapted to each patient so that, their effectiveness to be maximal. Rinosinusal tumours show particular elements of severity through late diagnosis due to lack of symptomatology, thus limiting the therapeutic means and their curative potential.In order to ensure a correct and complete treatment of this disease, an interdisciplinary collaboration between the ENT surgeon, ophthalmologist, neurosurgeon, imagist, oncotherapist, anatomopathologist, OMF surgeon both preoperatively in the setting of a therapeutic and postoperative strategy is absolutely necessary.Surgery has its well-established place in multimodality complex treatment whether it is curative or palliative.
Evaluation of Dental Crowding in Mixes Dentition. Comparison between two methods
Authors: Festila Dana , Pacurar Mariana , Golovcencu Loredana , Nenovici Dorin , Zalana Alexandru , Ghergie Mircea , Muntean Alexandrina , Enache Magdalena
Published: January 2020

Assessment of dental crowding in mixed dentition from sixty-two study models, maxillary and mandibular, by two different methods was attempted. A single examiner compared the following methods: Nance that used brass wire for measuring the available space between the mesial surfaces of the first permanent molars and L�ndstrom that includes the first permanent molars and used digital calipers. The results showed L�ndstrom method to be more reliable, reproducible and less time consuming.
The role of Narrow-band Imaging Cystoscopy in Non-muscular Invasive Bladder Cancer Management
Authors: Scarneciu Ioan , Banuta Ionut-Alexandru , Scarneciu Camelia Cornelia , Brinza Adrian , Maxim Laurian , Laculiceanu Alexandru Georgian , Porav Hodade Daniel , Todea Moga Ciprian , Ghirca Veronica , Orsolya Martha
Published: January 2020

Cystoscopy is the most common assessment method for the lower urinary tract, with the primary goal of establishing pathology management that can occur at this level. The most used method of performing cystoscopy is with white light, but it can lead to omission of lesions, especially when considering millimetric tumor formations. New light source technologies are under development, such as narrow-band cystoscopy. Overall, we examined a total of 416 patients, known with tumoral lesions, in WLI followed by reassessment in NBI at the same time and transurethral resection of tumor biopsy specimens. In 37.5% of the cases, NBI highlighted 1 to 3 tumors in addition to WLI. In 178 cases, tumor formations were newly discovered, and in 238 patients these were recurrent. Histopathological diagnosis indicated the pTa stage in 67.3% of cases, in 27.64% patients presented with pT1 stage and in 5.04% of cases CIS was identified. In terms of grading, G1 was identified in 205 of the cases, 124 patients presenting G2 and G3 occurred in 87 of the cases.
Comparative Study of Different Optimization Algorithms Used for Obtaining Diesel-Biodiesel Blends
Authors: Sandru Stefan , Onutu Ion
Published: January 2020

The purpose of this paper is to compare two different optimization methods, used in acquiring diesel-biodiesel blends. There were used five types of samples in order to enable the optimization of the final blend: there were chosen two types of hydrofined diesel fuel and there were synthesized three original types of biodiesel. The first optimization method used, dual simplex, is a classical method being used in solving linear programming problems. The second optimization method, the genetic algorithms, falls in the type of artificial intelligence algorithms, being an evolutionary method used when the problem requires searching an optimal solution in a great variety of valid solutions.
Comparative Study Regarding the Surface Roughness of Highly Viscous Flowable Composites After Immersion in Acidic Drinks
Authors: Nica Irina , Stoleriu Simona , Pancu Galina , Munteanu Adriana , Topoliceanu Claudiu , Iovan Alexandru , Dimbu Emilia , Andrian Sorin
Published: January 2020

The aim of the present study was to assess, by profilometry, the effect of different immersion regimes in Coca-Cola drink on the surface roughness of two highly viscous flowable composite resins. The studied materials were Gradia Direct LoFlo (GC Corporation,Tokyo, Japan) and Micro Esthetic flow-viscous (Bisico, Germany). Fifteen cylindrical samples having the of 5 mm and the thickness of 2 mm were made from each material using plastic molds placed on glass plates. The samples were light-cured for 40s on both sides through the glass plates, to ensure complete polymerization of the material. They were divided into two groups as follows: Group I. Gradia Direct LoFlo and Group II. Micro Esthetic flow-viscous. Specimens of each group were then randomly divided into 5 subgroups. In subgroup A (control group) 4 samples were kept only in artificial saliva. In subgroups B-E (each having 4 samples) the samples were immersed in Coca-Cola drink according to 4 different protocols. The mean values of roughness parameters, Ra, were calculated. The Kolmogorov-Smirnov normality test was used to determine the distribution of data in groups. ANOVA and Tukey post hoc statistical tests were used to compare the results from the groups. For both materials, the highest surface roughness was determined for the samples that were submerged 7 times/day in Coca Cola. The assessment of surface microstructure of the samples, after immersion, revealed for both materials a statistically significant increase of Ra values.
Chemical Composition and Rheological Parametrs of Helianthus Tuberosus Flour Used as a Sources of Bioactive Compounds in Bakery
Authors: Apostol Livia , Belc Nastasia , Gaceu Liviu , Vladut Valentin , Oprea Oana Bianca
Published: January 2020

The main aim of this study was to establish the optimum dose of Jerusalem artichoke (Helianthus tuberosus L.) flour to be used as a functional ingredient in the bakery products industry, from both a nutritional and technological point of view. H. tuberosus has an important functional potential given by its high content of inulin, minerals, amino acids, and organic silicon. In this work, H. tuberosus flour was used for the enrichment of wheat flour with functional biocompounds. The experiments evaluated the functional potential of wheat flour enriched with H. tuberosus flour, in different proportions, by examining the chemical composition and rheological behaviour of the doughs. It was found that incorporation up to a 5% into the formulation of wheat flour yielded an acceptable product in terms of rheological parameters, with improved nutritional and functional properties.
Atorvastatin in the Treatment of Dyslipidemic Patients with Very High Cardiovascular Risk and Nonalcoholic Fatty Liver Disease
Authors: Costache Irina Iuliana , Garleanu Irina , Aursulesei Viviana , Namat Razan Al , Ion Adriana , Miftode Radu Stefan , Tesloianu Dan , Iliescu Dan , Petris Antoniu Octavian , Costache Alexandru Dan , Popa Delia Melania , Timpau Amalia Stefana
Published: January 2020

Nonalcoholic fatty liver disease (NAFLD) is defined as the presence of hepatic fat accumulation after ruling out other causes of hepatic steatosis. The aim of the study is to identify the role of statin therapy in dyslipidemic patients with very high cardiovascular risk and NAFLD in achieving low density lipoprotein (LDL) cholesterol targets while also evaluating the changes in liver enzymes levels. This prospective study included 140 patients with NAFLD, hyperlipidemia and elevated cardiovascular risk. Serum lipids were assessed and liver function tests were performed at baseline and at 6 months follow up in 10 mg/ 20 mg daily atorvastatin treatment schedule. The results showed that total cholesterol, LDL cholesterol and triglycerides were significantly reduced at 6 months follow-up, while high density lipoprotein (HDL) cholesterol has not undergone important changes. Statin treatment significantly improved alanine aminotransferase serum levels, whereas aspartate aminotransferase levels were not significantly reduced between baseline and follow-up. Although statin therapy appears to be safe and effective for use in patients with NAFLD, an insufficient treatment is commonly observed in clinical practice, in order to avoid liver damage . NAFLD is not only a major cause of liver related morbidity and mortality, but also an independent cardiovascular risk factor, with cardiovascular mortality being the most important cause of death. Therefore, detecting and modifying risk factors without impairing liver function is desirable.
Depressive Clinical Manifestations Associated with Professional Aluminum Exposure
Authors: Handra Claudia Mariana , Ghita Isabel , Ulmeanu Alexandru , Enache Adelina-Mihaela , Epureanu Florin , Coman Oana Andreia , Coman Laurentiu , Fulga Ion
Published: January 2020

The aim of this study was to analyse the relation between professional aluminum exposure and depression. The study was performed on a number of 99 subjects exposed to aluminum, during a professional activity of 8 to 38 years in the aluminum production industry. The control group was represented by 36 subjects from the administrative sector. Chronically exposure to aluminum determined: headache, insomnia, apathy, asthenia, and a decrease in libido. Moreover, depression was more frequent in subjects chronically exposed to aluminum.
Myeloperoxidase (MPO), Possible Biomarker in Heart Failure
Authors: Tudorache Sorin Ioan , Coculescu Bogdan Ioan , Manole Gheorghe , Harsovescu Tudor , Tone Magdalena Bianca , Dinca Alexandra-Ligia
Published: January 2020

The justification for choosing and this enzyme marker to investigate the variation in serum concentration is supported by at least two arguments: cytokine myeloperoxidase at the level of the hypocritical myocardium, with or without contractile deficiency, can be secreted by any type of component or resident in the myocardium In cardiac failure, one of the forms that responds to the oxidative stress existing in the disease is MPO secretion that occurs early after some authors even during Class I contractile myocardial deficiency (NYHA classification).
The Morphological Substrate of the Sensory Pathways - Anatomy, Neurotransmission, Neurochemistry in Intraosseous Anaesthesia
Authors: Abbadi Abdel Karim Al Oweidi Al , Constantin Iulian , Romila Aurelia , Calin Alina Mihaela , Frincu Laurian Lucian , Dinu Ciprian , Elisei Alina Mihaela
Published: January 2020

In order to apply the most accurate and efficient locoregional techniques, the knowledge of the anatomical characteristics of the oro-maxilo-facial territory becomes imperatively necessary, without which the installation and the effect of the locoregional anaesthetics may be poor. Due to the many advantages it presents, locoregional anaesthesia is considered as a current use method during routine dental care. A good local or locoregional anaesthetic must be harmless to the tissues, must have no local or general toxicity, must lead to a high quality and durable anaesthetic, must not cause lesions to nerve endings, to be subject to dental surgery or of oral surgery, can be satisfactorily solved by using locoregional anaesthesia techniques, which are used successfully in patients with balanced psychic, who are calm and cooperative. A good anaesthesia suppresses pain, prevents pain-induced shock, and allows the dentist to work in optimal conditions. Although modern anaesthesia techniques have greatly changed the working environment in dental surgeries or outpatient facilities of oral and maxillo-facial surgery, emotion and anxiety, fears continue to exist in patients who will have to undergo care treatments. In order to apply the most accurate and effective locoregional anaesthetic techniques, the knowledge of the anatomical characteristics of oro-maxilo-facial territory becomes imperatively necessary, without which the location and effect of locoregional anaesthetics may be poor. The study includes 114 patients studied in the period 2015-2017 on which we used Stabident system intraosseous anaesthesia of company Fairfax under two available systems: Stabident Regular and Stabident Alternative. Intraosseous anaesthesia reduces the amount of injected anaesthesia, thus reducing the toxicity of anaesthetic procedures; this technique allows the use of vasoconstrictors for the immediate delivery of anaesthesia to the teeth affected by pulpitis without the risk of necrosis. Intraosseous anaesthesia is an anaesthesia technique similar to the ideal anaesthesia technique.
The Effect of STH Hypersecretion on Neuro-psychic Function
Authors: Cotoi Bogdan Virgil , Mavritsakis Nikolaos , Ganescu Anca , Ionescu Elena
Published: January 2020

C: I: Parhon and his colleagues have drawn attention to the existence of psychic disorders, especially manic-depressive and delusional, in a range of endocrine disorders such as acromegaly, gigantism, adipose-genital dystrophy, highlighting the aggressiveness of patients with acromegaly. A number of clinical trials have shown that pituitary dysfunction can be associated with schizophrenia and even epilepsy. In this study, 19 patients were diagnosed with acromegaly following STH dosing, resulting in values higher than the upper limit (ie above 5 ng / mL in men or over 10 ng / mL in females). These patients had complete neurological examination, electroencephalogram, psychological examination, and the Hamilton depression scale.
The Evaluation of Oxidative Stress Levels in Obesity
Authors: Epingeac Mirela Elena , Gaman Mihnea Alexandru , Diaconu Camelia Cristina , Gad Mohamed , Gaman Amelia Maria
Published: January 2020

The association between elevated values of reactive oxygen species and a decreased antioxidant capacity defines oxidative stress. Oxidative stress involvement is blamed in many diseases, including obesity. We evaluated oxidative stress levels by FORT (Free Oxygen Radical Testing � reactive oxygen species levels) and FORD (Free Oxygen Radical Defence � antioxidant capacity value) assays in obese subjects vs. controls. FORT values were high and FORD values were low in obese patients vs. controls, notably in obese subjects with comorbidities (diabetes, hypertension, dyslipidaemia, coronary heart disease, anaemia, hepatic steatosis). We found positive correlations between FORT values and total cholesterol, uric acid, triglycerides, LDL, body mass index, HDL/total cholesterol ratio, and negative correlations between FORT and age, HDL. FORD levels correlated oppositely to FORT. Our results suggest that obesity and oxidative stress are linked.
Validation and Quality Assurance of Ascorbic Acid Determination in Agricultural Products
Authors: Hegedus Ondrej , Szarka Katarina , Hegedusova Alzbeta , Godany Zsuzsanna , Slosar Miroslav , Nechifor Aurelia Cristina , Tonk Szende
Published: January 2020

The study describes a method for the determination of ascorbic acid (AA) with the technique of high performance liquid chromatography with UV detection (UV-HPLC) modified for routine analysis of agricultural products. For successful use of the method in the test laboratory practice, the reliability of using this method has been confirmed by validation. The repeatability of method has been observed, which is 2.80 - 5.55% for the various crops. Relative combined standard uncertainty has a value of 6.2%. The accuracy of the method is 103.2% and calculated as recovery of the standard addition. The value of the LOQ computed from the upper limit of reliability is 26.7 mg kg-1, which ensures safe determination of AA in every major agricultural crop.
A Kinetic Study of Glycerol Esterification with Acetic Acid Over a Commercial Amberlyst-35 Ion Exchange Resin
Authors: Banu Ionut , Bozga Grigore , Bumbac Gheorghe , Vintila Alin , Velea Sanda , Galan Ana-Maria , Bombos Mihaela , Blajan Olimpiu , Crucean Augustin Constantin
Published: January 2020

The increased quantities of glycerol available on the market initiated research efforts oriented to new valorization technologies, particularly by its conversion into medium tonnage chemicals, replacing petroleum derivatives. In this work it was investigated the valorization of glycerol by its transformation in glycerol acetates, by direct esterification with acetic acid, over a commercial Amberlyst-35 resin. Experiments were carried out batch-wise, in an autoclave reactor under controlled working conditions, at temperatures between 95 and 112 oC and initial acetic acid to glycerol molar ratios between 4 and 9. The experimental data evidenced that the glycerol conversion to monoacetate is faster than the next esterification steps. A relatively simple kinetic model was proposed and its parameters were evaluated from the experimental measurements. It proved reasonable predicting capacity for products distribution dependencies on the reactants molar ratio and reaction temperature.
Practical Considerations Regarding the Electrodeposition of Ni-Cu Layers as Potential Supercapacitors Plates
Authors: Ciobotea-Barbu Oana Claudia , Ciobotaru Ioana-Alina , Cojocaru Anca , Benga Florin-Mihai , Vaireanu Danut-Ionel
Published: January 2020

In this paper the properties of some Ni-Cu layers deposited onto a steel substrate were discussed. One has investigated the influence of the electrodeposition process on the final properties of the Ni-Cu layers, in order to see if these electrodeposited layers could be used as supercapacitor plates. The structural characterization was investigated by scanning electron microscopy and their composition by dispersive energy spectrometry. One has built a number of functional supercapacitors using Ni-Cu layer plates inserting in between them a separation membrane and their capacitance values were determined.
Correlations Between Known Prognostic Markers and Tumor - infiltrating Lymphocytes in Breast Cancer
Authors: Zgura Anca , Gales Laurentia , Haineala Bogdan , Bratila Elvira , Mehedintu Claudia , Andreescu Cristina Veronica , Berceanu Costin , Petca Aida , Barac Ramona Ileana , Ionescu Alec , Anghe Rodica
Published: January 2020

The presence of tumor-infiltrating lymphocytes (TILs) is associated with a favorable long-term outcome in breast cancer. The main objective of this study was to show that there is a correlation between known prognostic and predictive factors and TILs. We retrospectively identified 56 patients with human epidermal growth factor receptor-2 (HER2 +, n = 22) and HER2 negative (HER2-, n = 34) breast cancer diagnosed between 2012 and 2018 at the Institute of Oncology Prof. Dr. Alexandru Trestioreanu, Bucharest. Hematoxylin-eosin-stained slides of these paired samples were evaluated for stromal TILs. The present study reports that TILs can be used as a clinically useful biomarker that has the ability to stratify HER2 negative and HER2 positive patients in prognostic function, bringing relevant information in addition to the established prognostic factors.
The Influence of Wastewater from Paper Mills on the Biological Process in the Municipal Wastewater Treatment Plant
Authors: Tociu Carmen , Maria Cristina , Marcu Ecaterina , Ciobotaru Irina-Elena
Published: January 2020

Wastewaters resulting from paper mills have high organic loading that in most cases exceeds the maximum limits allowed for their discharge in the aquatic environment. In the context of concerns regarding the sustainable development of water resources, the identification of solutions for the optimal management of effluent treatment is a challenge of the modern society. This paper depicts the biological treatability of wastewaters resulting from the manufacturing of recycled paper and discusses their effect on the biological process after their admission in the municipal wastewater treatment plant. The Symons criterion and the Zahn-Wellens method were employed in order to study the biodegradability of organic substances as they are useful tools for prefiguring the behaviour of wastewaters during the secondary treatment step.
Considerations on the Ethiopathogenesis of Algae from the Primary Form of BMD
Authors: Coculescu Bogdan Ioan , Manole Gheorghe , Dinca Valeriu-Gabi , Dinca Alexandra-Ligia , Coculescu Elena Claudia
Published: January 2020

The study is motivated by the existence of a still controversial etiopathogen on Burning Mouth Syndrome. The objective of the study, which is carried out on a group of 103 sick of both sexes, presenting the Burning Mouth Disorder - the primary form, is to identify the prevalence of the disease and establish possible correlations with coexistence of age, gender and dyslipidemia as factors that can be considered as favoring the installation non-specific oral allergy. The conclusions of the research constitute an argument for admitting the hypothesis of the existence of a neuronal irrigation deficiency, manifested both at the conductive sensory fibers of the influx and, more preferably, at the sensory-sensorial cortex for pain and taste, or only at one of these levels. According to the hypothesis, neuronal suffering consists in a deficiency of energy production and use, induced by excessively local reactive oxygen species, through irrigation, developed by the presence of arteriosclerosis.
Multidisciplinary Approach on the Corrosion Behavior of Welded Nickel-free and Nickel-containing Stainless Steel Orthodontic Wires
Authors: Porojan Liliana , Birdeanu Mihaela , Porojan Sorin
Published: January 2020

The oral environment is responsible to the degradation of metal wires, with consequent release of metal ions in the oral cavity during corrosion, and welded joints are known as areas that are particularly susceptible to corrosion. The aim of the study was to achieve the corrosion behavior of welded Ni-free and Ni-containing stainless steel (SS) orthodontic wires. The morphology and the topography of the laser welded samples were investigated by scanning electron microscopy and atomic force microscopy. The electrochemical measurements calculated the values for corrosion potential, corrosion current and corrosion rate, for different pH values. Immersion in acidic solution had minimal effect on the corrosion on the joint regions. Ni-free SS wires proved to have a better corrosion resistance, improved by laser welding. Ni-containing SS wires are positive influenced by laser welding, relative to the corrosion behavior.
Soil Quality in the Poganis, Ramnei and Doclin Hills Measures of improvment
Authors: Nita Lucian , Tarau Dorin , Nita Simona , Heghes Alina , Bertici Radu , Dicu Daniel
Published: January 2020

The purpose of current research is part of the current scientific work and practice regarding the accumulation of knowledge on the structure and characteristics of the edaphic envelope and its quality in order to establish measures for its improvement. The researched issue covers an area of 113940 ha (of which 77039 ha, 67.61% are agricultural land), located in the Poganis, Ramnei and Doclin hills, namely Barzavei Plain. The paper provides basic information and methodological elements regarding the classification and evaluation of soil resources, thus integrating itself in the broader field of complex studies of natural resources and their valorisation thus assuring the environmental protection. This research takes place at a time when there is a high demand of education in soil-related issues from its perspective as a basis for the existence of human communities, component and support of terrestrial ecosystems. From this perspective, the physico-geographic conditions of soil formation and evolution are briefly, but succinctly presented, mentioning the way in which the particularities of the area within the space taken into consideration, of only 113940 ha as a stretch, determine a great diversity of ecological conditions. They are generated by the variability of the factors (cosmic-atmospheric and telluric-edaphic), for which the main processes of formation and evolution have achieved a different development and intensity, the result of which are different genetic types of soils (related or totally different) in constant evolution and demanding specific improvement measures.
Quantum Biological Thermodynamics with Finite Speed of the Cardio-Pulmonary System III-Comparison between stationary states and processes with or without quantum jump for a family members
Authors: Borcila Bogdan , Petrescu Stoian , Costea Monica , Petrescu Valeria , Bolohan Romi
Published: January 2020

The paper presents studies based on measurements of the Fundamental State Parameters (FH, FL, Rf and N, the quantum interaction number between the Heart and the Lungs) of the Cardio-Pulmonary System by persons belonging to a family, based on established protocols, for a more complete knowledge of its functioning. Thus, the persons are different in terms of age, sex and physical characteristics (weight, height, and lifestyle), they have parental or cohabiting statuses (mother-son, father-son, husband-wife). They perform the same activities or have different concerns with a higher or lower Power consumption. The diagrams constructed using the Fundamental State Parameters in Quantum Biological Thermodynamics with Finite Speed (QBTFS) allow the study of Stationary Quantum States and the interaction Processes between them (with or without Quantum Jump), which provides very important data on the functional characteristics of the Cardio-Pulmonary System for each person. The information obtained within QBTFS of the Cardio-Pulmonary System is particularly useful for the personalized design of the Hearts and artificial Lungs according to the physical and physiological particularities of different patients.
Theoretical and Experimental Results on the Recovery of Potato Processing Residuals by Anaerobic Digestion
Authors: Dima Andreea D. , Mateescu Carmen , Parvulescu Oana C. , Lungulescu Eduard M. , Nicula Nicoleta O.
Published: January 2020

Anaerobic digestion of organic matter with high moisture content has proven to be a suitable method for disposal of wet organic residuals with several advantages compared to other treatment technologies. This paper aimed at evaluating the theoretical and experimental biomethane potential of food processing residuals that are responsible for negative environmental impact, with exemplification for the potato processing waste. The biomethane potential is a useful parameter to assess the economic efficiency of anaerobic digestion processes as it can considerably influence the efficiency and the economic feasibility of the energy recovery technologies. Both experimental and theoretical biomethane potentials of potato waste in mesophilic anaerobic digestion as well as biodegradability of the substrate were estimated. Moreover, effects of microalgal extract addition on the digestion of potato waste were examined in an attempt to stimulate the anaerobic digestion. Cone model and a modified Gompertz model were used to predict the dynamics of biomethane production.
Antimicrobial Activity of Biosynthesized Silver Nanoparticles Compared to Standard Antibiotics Used in ORL Infections
Authors: Tischer (Tucuina) Alina Andreea , Vaduva Delia Berceanu , Balica Nicolae , Heghes Alina , Cheveresan Adelina , Voicu Mirela , Horhat Delia , Manea Horatiu Cristian , Poenaru Marioara
Published: January 2020

In recent years, bacterial infections in hospitals have grown particularly due to the development of antibiotic resistance. Recent research targets the discovery of new antibiotics that exhibit broad spectrum of action without adverse effects or minimizing adverse effects. In this study, the activity of biosynthesized silver nanoparticles against three bacteria commonly found in infectious diseases in the ORL sphere was evaluated. The recorded data revealed an activity comparable to that of the standard antibiotics used in these types of infections, with the observation that the activity of the nanoparticles could also be observed in the particular cases of antibiotic resistance.
Information Design for “Weak Signal” detection and processing in Economic Intelligence: A case study on Health resources
Authors: Sidhom Sahbi , Lambert Philippe
Published: January 2020

The topics of this research cover all phases of “Information Design” applied to detect and profit from weak signals in economic intelligence (EI) or business intelligence (BI). The field of the information design (ID) applies to the process of translating complex, unorganized or unstructured data into valuable and meaningful information.  ID   practice     requires an interdisciplinary approach, which combines skills in graphic design (writing, analysis processing and editing), human performances technology and human factors. Applied in the context of information system, it allows end-users to easily detect implicit topics known as “weak signals” (WS). In our approach to implement the ID, the processes cover the development of a knowledge management (KM) process in the context of EI. A case study concerning information monitoring health resources is presented using ID processes to outline weak signals. Both French and American bibliographic databases were applied to make the connection to multilingual concepts in the health watch process.
Knowledge and social networks: New dimensions of economic interaction between firms
Authors: Steiner Michael , Ploder Michael
Published: January 2020

The paper explores the form and content of economic interaction of firms based on various concepts of agglomeration and social networks. It uses a case study of the machinery sector in the region of Styria as empirical background. Starting with types of clustering – the model of pure agglomeration, the industrial-complex model and the social-network model - the paper argues that certain geographical agglomerations allow different types of networks and different patterns of behaviour. Thus different forms of learning, knowledge sharing and knowledge creation. Some “stylized facts” in support of this perspective are derived from an analysis of a regional network. This network comprises individualistic open systems consisting of several areas which overlap. Physical linkages between these networks are weak, but intersections based on cooperative R&D and R&D infrastructure, qualification and informal exchanges are evident. From a regional perspective it can be seen to dominate. Despite evident sectoral concentrations direct links to the prevailing science base appear more significant as binding factors than long term supplier networks. These relationships are interpreted in terms of their need for proximity, their durability and above all their direction of knowledge dependency.