bluuebunny/crossref_metadata_2025 huggingface dataset:
A curcumin derivative, WZ35, suppresses hepatocellular cancer cell growthviadownregulating YAP-mediated autophagy
Authors: Wang Lihua , Zhu Zheng , Han Lei , Zhao Liqian , Weng Jialei , Yang Hongbao , Wu Shijia , Chen Kaiyuan , Wu Liang , Chen Tongke
Published: May 2019

HCC is a common cancer type in the world. Here, we found WZ35, a novel derivative of curcumin, could notably suppress HCC cell growthviainhibiting YAP controlled autophagy, highlighting the potent anti-tumor activity of WZ35 in liver cancer therapy.
Fight the flow: the role of shear in artificial rheotaxis for individual and collective motion
Authors: Baker Remmi , Kauffman Joshua E. , Laskar Abhrajit , Shklyaev Oleg E. , Potomkin Mykhailo , Dominguez-Rubio Leonardo , Shum Henry , Cruz-Rivera Yareslie , Aranson Igor S. , Balazs Anna C. , Sen Ayusman
Published: May 2019

To navigate in complex fluid environments, swimming organisms like fish or bacteria often reorient their bodies antiparallel or against the flow, more commonly known as rheotaxis.
Synthesis of spiroimidazopyridineoxindole, spiropyridopyrimidineoxindole and spiropyridodiazepineoxindole derivatives based on heterocyclic ketene aminals via a four-component reaction
Authors: Rahimi Fatemeh , Bayat Mohammad , Hosseini Hajar
Published: May 2019

A simple and efficient approach to the synthesis of three new classes of fused spiropyridineoxindoles using heterocyclic ketene aminals.
Efficient visible-light driven N2 fixation over two-dimensional Sb/TiO2 composites
Authors: Zhao Zhenqing , Hong Song , Yan Chao , Choi Changhyeok , Jung Yousung , Liu Yongchao , Liu Shizhen , Li Xin , Qiu Jieshan , Sun Zhenyu
Published: May 2019

Photochemical ammonia production under ambient conditions remains a grand challenge.
Transition metal complex dye-sensitized 3D iodoplumbates: syntheses, structures and photoelectric properties
Authors: Yue Cheng-Yang , Yue Yun-Di , Sun Hai-Xiao , Li Dong-Yang , Lin Na , Wang Xin-Ming , Jin Ying-Xue , Dong Yu-Han , Jing Zhi-Hong , Lei Xiao-Wu
Published: May 2019

The first types of transition metal complex cationic dye-sensitized 3D hybrid porous iodoplumbates exhibiting outstanding visible light-driven photoelectric properties.
Photo-accelerated “click” reaction between diarylsydnones and ring-strained alkynes for bioorthogonal ligation
Authors: Zhang Xiaocui , Wu Xueting , Jiang Shichao , Gao Jingshuo , Yao Zhuojun , Deng Jiajie , Zhang Linmeng , Yu Zhipeng
Published: May 2019

A novel photo-click ligation reaction between diarylsydnones and ring-strained alkynes, exhibiting decent bioorthogonality, was established under 405 nm light irradiation.
Efficient modulation of photoluminescence by hydrogen bonding interactions between inorganic [MnBr4]2− anions and organic cations
Authors: Gong Liao-Kuo , Hu Qian-Qian , Huang Fu-Quan , Zhang Zhi-Zhuan , Shen Nan-Nan , Hu Bing , Song Ying , Wang Ze-Ping , Du Ke-Zhao , Huang Xiao-Ying
Published: May 2019

The difference in the hydrogen bonding interactions originating from different organic cations brings photoluminescence with distinct quantum yields.
Sensitive discrimination of single nucleotide variants using a PDA microtube waveguide platform with heterogeneous CHA amplification and competitive inhibition strategy
Authors: Liu Funing , Cheng Junjie , Feng Xiaohui , Yang Kexin , Zhang Hongli , Hu Jingang , Wang Mengqiao , Yu Yue , Zhang Qijin , Zou Gang
Published: May 2019

The CHA system preferentially amplifies the target signal while the competitive system preferentially inhibits the SNV signal using PDA microtubes.
A highly conductive, transparent molecular charge-transfer salt with reversible lithiation
Authors: Guan Ying-Shi , Hu Yong , Zhang Hanguang , Wu Gang , Yan Hao , Ren Shenqiang
Published: May 2019

Here, we describe the high conductivity in a molecular charge-transfer hydrocarbon both as a bulk solid and films.
Visible light induced controlled cationic polymerization by in situ generated catalyst from manganese carbonyl
Authors: Li Jiajia , Zhang Mengmeng , Pan Xiangqiang , Zhang Zhengbiao , Perrier Sébastien , Zhu Jian , Zhu Xiulin
Published: May 2019

Controlled cationic polymerization of various vinyl ethers is achieved under light radiation, utilizing commercially available reagents, under mild conditions and the molecular weight distributions can be modulated by simply regulating the irradiation time.
A simple mix-and-read bacteria detection system based on a DNAzyme and a molecular beacon
Authors: Cao Ting , Wang Yongcheng , Zhao Ling-Li , Wang Ye , Tao Ye , Heyman John A. , Weitz David A. , Zhou Ying-Lin , Zhang Xin-Xiang
Published: May 2019

A simple improved mix-and-read method for the detection of bacteria is developed based on a DNAzyme and a molecular beacon.
Determining short-lived solid forms during phase transformations using molecular dynamics
Authors: Larsen Anders S. , Olsen Mark A. , Moustafa Hadeel , Larsen Flemming H. , Sauer Stephan P. A. , Rantanen Jukka , Madsen Anders Ø.
Published: May 2019

We demonstrate that elusive high-energy metastable crystal structures can be determined from molecular dynamics simulations.
A first attempt investigation on crystallization screening and crystal quality of lysozyme under different simulated gravities in a large-gradient magnetic field
Authors: Wu Zi-Qing , Liu Yong-Ming , Liu Chan , Chen Jing-Jie , Chen Liang-Liang , Zhang Tuo-Di , Zhou Ren-Bin , Yang Chang-Qing , Shang Peng , Yin Da-Chuan
Published: May 2019

A magnetic field has been proved useful in protein crystallization in that it can help to improve the crystal quality, which is essential for high-resolution diffraction using crystallography.
Energetics of exciton binding and dissociation in polythiophenes: a tight binding approach
Authors: Bombile Joel H. , Janik Michael J. , Milner Scott T.
Published: May 2019

A tight-binding exciton model that describes the continuum from the bound exciton to the free hole and electron polarons in conjugated polymer chains is introduced and applied to polythiophenes.
On the ligand–core interaction in ligand-protected gold superatoms. Insights from Au25(XR)18 (X = S, Se, Te) via relativistic DFT calculations
Authors: Muñoz-Castro Alvaro
Published: May 2019

Different chalcogen anchor atoms lead to changes in excited state properties in Au25(XR)18 clusters.
Oxygen transport and surface exchange mechanisms in LSCrF–ScCeSZ dual-phase ceramics
Authors: Shen Zonghao , Skinner Stephen J. , Kilner John A.
Published: May 2019

A schematic of the potential mechanism of the up-hill like behaviour in the LSCrF phase in the fused pellet.
BiOBr-photocatalyzedcis–transisomerization of 9-octadecenoic acids in different atmospheres
Authors: Zhang Xiaochao , Wei Jiabing , Ren Guangmin , Zhang Changming , Zheng Zhanfeng , Fan Caimei
Published: May 2019

Investigating systematically BiOBr photocatalyzed oleic acid isomerization in different (air, N2, and O2) atmospheres and thecis–transisomerization mechanism for the first time.
On isothermality in some commonly used plug flow reactors for X-ray based investigations of catalysts
Authors: Newton Mark A. , Checchia Stefano , Knorpp Amy J. , Stoian Dragos , van Beek Wouter , Emerich Hermann , Longo Alessandro , van Bokhoven Jeroen A.
Published: May 2019

We compare two reactor setups commonly used to make operando measurements of catalyst behavior using X-rays in terms of the degree to which they may be considered to yield radial and axial isothermality.
Reactivity of a gold(i)/platinum(0) frustrated Lewis pair with germanium and tin dihalides
Authors: Hidalgo Nereida , Bajo Sonia , Moreno Juan José , Navarro-Gilabert Carlos , Mercado Brandon Q. , Campos Jesús
Published: May 2019

The rich reactivity of tetrylene dihalides towards a metallic FLP: phosphine exchange reactions and formation of homo and heterobimetallic compounds.
Organic cation directed one-dimensional cuprous halide compounds: syntheses, crystal structures and photoluminescence properties
Authors: Yue Cheng-Yang , Lin Na , Gao Lu , Jin Ying-Xue , Liu Zhao-Yang , Cao Yao-Yao , Han Sha-Sha , Lian Xi-Kai , Hu Bing , Lei Xiao-Wu
Published: May 2019

One-dimensional organic–inorganic hybrid cuprous halides exhibit strong tunable photoluminescence from cyan to red emissions with large Stokes shifts.
A molecular electron density theory study of the insertion of CO into frustrated Lewis pair boron-amidines: a [4 + 1] cycloaddition reaction
Authors: Ríos-Gutiérrez Mar , Domingo Luis R. , Rojas René S. , Toro-Labbé Alejandro , Pérez Patricia
Published: May 2019

The insertion of CO into hydrogenated boron-amidine yielding five-membered diazaborolone has been studied within the molecular electron density theory (MEDT) at the DFT ωB97X-D/6-311G(d,p) level.
The synthesis and biological evaluation of novel gardenamide A derivatives as multifunctional neuroprotective agents
Authors: Zhang Zuzhi , Wang Yujun , Zhang Yanchun , Li Jiaming , Huang Weijun , Wang Lei
Published: May 2019

A novel series of gardenamide A derivatives was designed and synthesized as multifunctional neuroprotective agents with potential as anti-Alzheimer's disease agents.
Bionic synthesis of a magnetic calcite skeletal structure through living foraminifera
Authors: Magnabosco Giulia , Hauzer Hagar , Fermani Simona , Calvaresi Matteo , Corticelli Franco , Christian Meganne , Albonetti Cristiano , Morandi Vittorio , Erez Jonathan , Falini Giuseppe
Published: May 2019

This communication describes the bionic preparation of a composite material in which fluorescent magnetite nanoparticles are included within the calcitic skeletal structure of the foraminifer Amphistrigina lessoni.
From waste epoxy resins to efficient oil/water separation materialsviaa microwave assisted pore-forming strategy
Authors: Tian Fei , Yang Yang , Wang Xiong-Lei , An Wen-Li , Zhao Xu , Xu Shimei , Wang Yu-Zhong
Published: May 2019

Waste epoxy resins were converted directly into oil/water separation materialsviasimple microwave-assisted pore formation.
Effect of furan π-spacer and triethylene oxide methyl ether substituents on performance of phenothiazine sensitizers in dye-sensitized solar cells
Authors: Buene Audun Formo , Boholm Nanna , Hagfeldt Anders , Hoff Bård Helge
Published: May 2019

Synthesis and characterization of three phenothiazine dyes inspired by literature dye EO3 improving absorption properties and photovoltaic performance in DSSCs.
Theoretical investigation of the electronic structure and photophysical properties of a series of Ir(iii) complexes bearing pentafluorosulfanyl groups
Authors: Gao Jing , Li Xin , Han Deming , Li Jiawei , Shang Xiaohong
Published: May 2019

The electronic structure, absorption and emission spectra, charge injection/transport ability and phosphorescence quantum efficiency of a series of cyclometalated iridium(iii) complexes with different ancillary ligands are studied using density functional theory (DFT) and time-dependent density functional theory (TDDFT) methods.
Synthesis of high surface area transition metal sponges and their catalytic properties
Authors: Islam Md. Tariqul , Rosales Jose , Saenz-Arana Ricardo , Arrieta Roy , Kim Hoejin , Sultana Kazi Afroza , Lin Yirong , Villagran Dino , Noveron Juan C.
Published: May 2019

Facile synthesis of cobalt, nickel, and copper sponges and their catalytic properties for the reduction of 4-nitrophenol, methyl orange, and methylene blue.
Mechanisms and advanced photothermal modelling of laser-induced shape transformations of colloidal gold nanorods by nanosecond laser pulses
Authors: Mansour Yehia , Battie Yann , En Naciri Aotmane , Chaoui Nouari
Published: May 2019

We propose an advanced photothermal model based on a modified Takami model (MTM) to explain the mechanisms of shape changes of colloidal gold nanorods (NRs) induced by nanosecond laser pulses.
Hybrid vesicles as intracellular reactive oxygen species and nitric oxide generators
Authors: Zhang Yan , Gal Noga , Itel Fabian , Westensee Isabella N. , Brodszkij Edit , Mayer Daniel , Stenger Steffen , Castellote-Borrell Miquel , Boesen Thomas , Tabaei Seyed R. , Höök Fredrik , Städler Brigitte
Published: May 2019

Artificial organelles are envisioned as nanosized assemblies with intracellular biocatalytic activity to provide the host cells with non-native or missing/lost function.
Bidirectional ROMP of paracylophane-1,9-dienes to tri- and penta-block p-phenylenevinylene copolymers
Authors: Komanduri Venukrishnan , Kumar Dharam R. , Tate Daniel J. , Marcial-Hernandez Raymundo , Lidster Benjamin J. , Turner Michael L.
Published: May 2019

Dialkoxy and dialkyl substituted paracyclophane-1,9-dienes undergo bidirectional ring opening metathesis polymerisation (ROMP) on addition of bifunctional Hoveyda–Grubbs initiators.
Ultrathin 2D Cu-porphyrin MOF nanosheets as a heterogeneous catalyst for styrene oxidation
Authors: Xiao Yawen , Guo Wenxiao , Chen Huanhuan , Li Hongfeng , Xu Xiujie , Wu Peng , Shen Yu , Zheng Bing , Huo Fengwei , Wei Wei David
Published: May 2019

Cu-TCPP nanosheets exhibit a high density of active sites and low diffusion barriers for styrene epoxidation.
Carbon-nanotube-filled catalyst-free thermoset polyurea composites towards achieving recyclability, weldability and permanent shape reconfiguration
Authors: Jiang Liang , Liu Qinfeng , Lei Yuan , Wang Yi , Zhao Yuanyang , Lei Jingxin
Published: May 2019

The incorporation of carbon nanotubes into catalyst-free thermoset polyurea composites can achieve their excellent reprocessability by hot press or micro injection.
Hydrophobics of CnTAB in an aqueous DMSO–BSA nanoemulsion for the monodispersion of flavonoids
Authors: Sachin K. M. , Singh Man
Published: May 2019

The wavy zone of flavonoid in aq-DMSO <10% DMSO predicts the kinetic energy and resultant molecular dynamics.
Synthesis of (Bi1−xSbx)2S3solid solutionsviathermal decomposition of bismuth and antimony piperidinedithiocarbamates
Authors: Kun Walter N. , McNaughter Paul D. , Nyamen Linda D. , Spencer Ben F. , O'Brien Paul , Ndifon Peter T. , Revaprasadu Neerish
Published: May 2019

A full range of (Bi1−xSbx)2S3solid solutions from bismuth and antimony piperidine dithiocarbamate complexes is reported.
Cu(ii)/Ni(ii)–organic frameworks constructed from the homometallic clusters by 5-(2-carboxyphenoxy)isophthalic acid and N-ligand: synthesis, structures and visible light-driven photocatalytic properties
Authors: Xu Qi-Wei , Wang Qiu-Shuang , Li Shan-Shan , Li Xia
Published: May 2019

Four Cu(ii)/Ni(ii)-metal–organic frameworks were constructed from different homometallic clusters by O-cpia/N-ligands. Cu(ii)-complexes show highly efficient photocatalysts for the degradation of RhB under visible light irradiation.
Enhanced luminescence and tunable magnetic properties of lanthanide coordination polymers based on fluorine substitution and phenanthroline ligand
Authors: Feng Xun , Shang Yapei , Zhang Heng , Li Rongfang , Wang Weizhou , Zhang Daoming , Wang Liya , Li Zhongjun
Published: May 2019

Lanthanide coordination polymers with F-substituted carboxylate tectonics and phenanthroline ligands exhibit emission from the visible to near-infrared region with long lifetime. Dy(iii) compounds show temperature dependent and field induced single molecule magnetism.
Tailoring optical cross sections of gold nanorods at a target plasmonic resonance wavelength using bromosalicylic acid
Authors: Zou Weiwei , Xie Hao , Ye Yang , Ni Weihai
Published: May 2019

We demonstrate finely tailoring optical cross sections of AuNRs at a fixed target resonance wavelength, on the basis of AuNR overgrowth using a binary surfactant mixture consisting 5-bromosalicylic acid (BSA) and cetyltrimethylammonium bromide (CTAB).
A flexible Ti3C2Tx (MXene)/paper membrane for efficient oil/water separation
Authors: Saththasivam Jayaprakash , Wang Kui , Yiming Wubulikasimu , Liu Zhaoyang , Mahmoud Khaled A.
Published: May 2019

A highly hydrophilic and oleophobic membrane based on Ti3C2Tx (MXene) coated paper demonstrated high separation efficiency for oil/water emulsions with excellent antifouling properties.
Microbial synthesis of hollow porous Prussian blue@yeast microspheres and their synergistic enhancement of organic pollutant removal performance
Authors: Chen Si , Bai Bo , Xu Xiaohui , Hu Na , Wang Honglun , Suo Yourui
Published: May 2019

Prussian blue wasin situgrown onS. cerevisiaecells to obtain PB@yeast, which exhibited synergistically enhanced activity in dye wastewater treatment.
Enhanced efficiency and high temperature stability of hybrid quantum dot light-emitting diodes using molybdenum oxide doped hole transport layer
Authors: Yun Jinyoung , Kim Jaeyun , Jung Byung Jun , Kim Gyutae , Kwak Jeonghun
Published: May 2019

QLEDs introducing a p-doped HTL exhibit stable operation at high temperature up to 400 K.
Heteropoly acid-encapsulated metal–organic framework as a stable and highly efficient nanocatalyst for esterification reaction
Authors: Zhang Qiuyun , Yang Tingting , Liu Xiaofang , Yue Caiyan , Ao Liufang , Deng Taoli , Zhang Yutao
Published: May 2019

Silicotungstic acid (HSiW) encapsulated UiO-66 nanocatalyst have been successfully synthesized by one-pot synthesis strategy and used as a stable and highly efficient catalyst for esterification.
Multiple representations in the development of students’ cognitive structures about the saponification reaction
Authors: Baptista Mónica , Martins Iva , Conceição Teresa , Reis Pedro
Published: May 2019

The purpose of this study was to understand how the use of multiple representations (MR), during a sequence of lessons on the saponification reaction, can help students develop their cognitive structures. We examined (i) the effect of the teaching sequence with MR on the development of the students’ cognitive structures and (ii) how, according to the students, that sequence helped them to develop their cognitive structures. This study was conducted in three Grade 12 classes, including a total of 68 students. This study follows a pre-experimental one group pretest–posttest design, providing an intervention during the experiment. We used two data collection instruments: a Word Association Test (WAT) and a focus group interview. The results obtained from the WAT show that the students’ cognitive structures progressed from the pretest to posttest, with an increase in the number of response words and connections between words, and with a change in the nature of these connections. The results suggest that this development was influenced by the way students used MR, making use of the three MR functions proposed by Ainsworth (2006, 2008). The students recognized that the combination of the three MR functions allowed them to move across representation levels (macroscopic, symbolic and submicroscopic) and to develop a deeper and more structured understanding of the concepts related to the saponification reaction.
Snapshots of magnesium-centred diborane heterolysis by an outer sphere SN2 process
Authors: Pécharman Anne-Frédérique , Hill Michael S. , McMullon Grace , McMullin Claire L. , Mahon Mary F.
Published: May 2019

Reactions of a magnesium diboranate as a source of [Bpin]−anions are initiated by ‘outer sphere’ attack of CN bonded substrates.
Faradaic reactions in capacitive deionization for desalination and ion separation
Authors: Yu Fei , Wang Lei , Wang Ying , Shen Xiaojie , Cheng Yujuan , Ma Jie
Published: May 2019

The performance of faradaic electrode materials in desalination, the removal of heavy metals, and ion separation is presented.
Hydrophobic perovskites based on an alkylamine compound for high efficiency solar cells with improved environmental stability
Authors: Jung Mi-Hee
Published: May 2019

We used hexylamine (CH3(CH2)4CH2NH2, HA) for a quasi-2D HA(CH3NH3)n−1PbnI3n+1 (n = 1, 2, 3, and 4) perovskite, which had sufficient long alkyl chains to maintain the chemical stability of the perovskite and exhibited an appropriate band gap for application to solar cells as a light absorber.
A new paradigm of ultrathin 2D nanomaterial adsorbents in aqueous media: graphene and GO, MoS2, MXenes, and 2D MOFs
Authors: Zhao Pin , Jian Meipeng , Zhang Qi , Xu Rongming , Liu Ruiping , Zhang Xiwang , Liu Huijuan
Published: May 2019

Due to the high surface area, atomic-level thickness, and abundant exposed active sites, 2D nanomaterials are regarded potential high-performance adsorbents. We review four representative nanomaterials, graphene, MoS2, MXenes, and MOFs, for this application.
A CoP/CdS/WS2 p–n–n tandem heterostructure: a novel photocatalyst for hydrogen evolution without using sacrificial agents
Authors: Zhong Yueyao , Wu Yongzhong , Chang Bin , Ai Zizheng , Zhang Kang , Shao Yongliang , Zhang Lei , Hao Xiaopeng
Published: May 2019

Photocatalytic hydrogen evolution from pure water and bifunctional photocatalytic reaction are realized using a CoP/CdS/WS2 photocatalyst, which has a p–n–n tandem heterostructure.
The surface engineering of cobalt carbide spheres through N, B co-doping achieved by room-temperature in situ anchoring effects for active and durable multifunctional electrocatalysts
Authors: Ma Xinzhi , Li Kaiyue , Zhang Xiao , Wei Bo , Yang Huan , Liu Lina , Zhang Mingyi , Zhang Xitian , Chen Yujin
Published: May 2019

B doping and surface engineering of a N-containing Co3C alloy at room temperature are simultaneously achieved, endowing the resultant catalyst with excellent and stable multifunctional activities.
Flexible self-powered textile formed by bridging photoactive and electrochemically active fiber electrodes
Authors: Gao Zhen , Liu Peng , Fu Xuemei , Xu Limin , Zuo Yong , Zhang Bo , Sun Xuemei , Peng Huisheng
Published: May 2019

By bridging photoactive and electrochemically active fibers via warp yarns using an industrial loom, we realized desirable continuous and large-scale production of self-powered textiles, which have remained challenging in the past decade. This work possibly represents a new advancement for flexible integrated power systems via weaving.
Rational construction of MoS2/Mo2N/C hierarchical porous tubular nanostructures for enhanced lithium storage
Authors: Yang Song , Zhang Yunqiang , Wang Shulan , Shi Jian , Liu Xuan , Li Li
Published: May 2019

The fabrication of a unique heterostructure composed of MoS2/Mo2N with nitrogen doped carbon was synthesized by a stepwise cooperative assembly-directed strategy.
Controllable and large-scale supramolecular vesicle aggregation: orthogonal light-responsive host–guest and metal–ligand interactions
Authors: Du Guangyan , Lou Lingyun , Guan Shuwen , Peng Yuanyuan , Qiao Hongwei , Liu Pingli , Wu Dan
Published: May 2019

On the basis of the host–guest molecular recognition interaction between β-cyclodextrin and azobenzene, two kinds of supramolecular self-assemblies (Py-CD⊃Azo-C and Py-CD⊃Azo-C3) were constructed.
Cathode interlayer-free organic solar cells with enhanced device performance upon alcohol treatment
Authors: Chen Xuebin , Zhu Bei , Kan Bin , Gao Ke , Peng Xiaobin , Cao Yong
Published: May 2019

Solvent treatment was used to simplify the device structure and enhance the device performance of porphyrin-based small molecule solar cells.
Modulating charge transport characteristics of bis-azaisoindigo-based D–A conjugated polymers through energy level regulation and side chain optimization
Authors: Huang Kaiqiang , Zhao Xue , Du Yuchang , Kim Sanghyo , Wang Xiaohong , Lu Hongbo , Cho Kilwon , Zhang Guobing , Qiu Longzhen
Published: May 2019

Six donor–acceptor (D–A) conjugated polymers, P1–P6, based on the novel electron acceptors bis-isoindigo (BIID) and bis-azaisoindigo (BAID), were designed and synthesized for solution-processed organic field-effect transistors.
Advances in the molecular regulation of endothelial BMP9 signalling complexes and implications for cardiovascular disease
Authors: Wood Jennifer H. , Guo Jingxu , Morrell Nicholas W. , Li Wei
Published: May 2019

Bone morphogenetic protein 9 (BMP9), a member of the transforming growth factor β (TGFβ) superfamily, is a circulating vascular quiescence and endothelial protective factor, accounting for the majority of BMP activities in plasma. BMP9 and BMP10 bind preferentially to the high-affinity type I receptor activin receptor-like kinase 1 on vascular endothelial cells. Recently, many reports have highlighted the important roles of BMP9 in cardiovascular disease, particularly pulmonary arterial hypertension. In vivo, BMP9 activity and specificity are determined by tightly regulated protein–protein recognition with cognate receptors and a co-receptor, and may also be influenced by other proteins present on the endothelial cell surface (such as low-affinity receptors) and in circulation (such as TGFβ family ligands competing for the same receptors). In this review, we summarise recent findings on the role and therapeutic potential of BMP9 in cardiovascular disease and review the current understanding of how the extracellular protein–protein interaction milieu could play a role in regulating endothelial BMP9 signalling specificity and activity.
Biology is the root of variability: cautionary tales in Caenorhabditis elegans biology
Authors: Pho Kim B. , MacNeil Lesley T.
Published: May 2019

Reproducibility is critical for the standardization, interpretation, and progression of research. However, many factors increase variability and reduce reproducibility. In Caenorhabditis elegans research, there are many possible causes of variability that may explain why experimental outcomes sometimes differ between laboratories and between experiments. Factors contributing to experimental variability include the genetic background of both C. elegans and its bacterial diet, differences in media composition, intergenerational and transgenerational effects that may be carried over for generations, and the use of chemicals or reagents that may have unexpected consequences. This review summarizes sources of variability in C. elegans research and serves to identify laboratory practices that could influence reproducibility.
Working Memory Profiles of Children With Dyslexia, Developmental Language Disorder, or Both
Authors: Gray Shelley , Fox Annie B. , Green† Samuel , Alt Mary , Hogan Tiffany P. , Petscher Yaacov , Cowan Nelson
Published: May 2019

Purpose

Compared to children with typical development, children with dyslexia, developmental language disorder (DLD), or both often demonstrate working memory deficits. It is unclear how pervasive the deficits are or whether the deficits align with diagnostic category. The purpose of this study was to determine whether different working memory profiles would emerge on a comprehensive battery of central executive, phonological, visuospatial, and binding working memory tasks and whether these profiles were associated with group membership.

Method

Three hundred two 2nd graders with typical development, dyslexia, DLD, or dyslexia/DLD completed 13 tasks from the Comprehensive Assessment Battery for Children–Working Memory (
Gray, Alt, Hogan, Green, & Cowan, n.d.
) that assessed central executive, phonological, and visuospatial/attention components of working memory.

Results

Latent class analyses yielded 4 distinct latent classes: low overall (21%), average with high number updating (30%), average with low number updating (12%), and high overall (37%). Children from each disability group and children from the typically developing group were present in each class.

Discussion

Findings highlight the importance of knowing an individual child's working memory profile because working memory profiles are not synonymous with learning disabilities diagnosis. Thus, working memory assessments could contribute important information about children's cognitive function over and above typical psychoeducational measures.
Motor Imagery Practice and Increased Tongue Strength: A Case Series Feasibility Report
Authors: Szynkiewicz Sarah H. , Nobriga Christina V. , O'Donoghue Cynthia R. , Becerra Benjamin J. , LaForge Garret
Published: May 2019

Purpose

The aim of the study was to determine the effects of a 6-week progressive resistance tongue exercise protocol in mental practice form on tongue strength. Investigation begins in typically aging adults, a population susceptible to reduced tongue strength and dysphagia secondary to age-related changes in the swallowing mechanism. It was hypothesized that typically aging adults who perform a 6-week progressive resistance tongue exercise protocol in mental practice form would increase tongue strength.

Method

A prospective, case series intervention study was used. Six healthy women aged 53–78 years completed a 6-week mental practice tongue resistance exercise program utilizing motor imagery to imagine completion of tongue exercises. The main outcome was mean isometric maximum tongue pressures (tongue strength), which were collected at baseline and Weeks 2, 4, and 6 using the Iowa Oral Performance Instrument (
IOPI Medical, 2013
).

Results

By Week 6 of the study, all participants had significantly increased their tongue strength compared to baseline.

Conclusions

The findings indicate that mental practice using motor imagery for tongue exercise may improve tongue strength in healthy individuals at risk for dysphagia and may thus represent a promising direction warranting further investigation in typically aging individuals and patients with dysphagia and decreased tongue strength.
Predictive multi‐view content buffering applied to interactive streaming system
Authors: Costa T.S. , Andrade M.T. , Viana P.
Published: May 2019

This Letter discusses the benefits of introducing Machine Learning techniques in multi‐view streaming applications. Widespread use of machine learning techniques has contributed to significant gains in numerous scientific and industry fields. Nonetheless, these have not yet been specifically applied to adaptive interactive multimedia streaming systems where, typically, the encoding bit rate is adapted based on resources availability, targeting the efficient use of network resources whilst offering the best possible user quality of experience (QoE). Intrinsic user data could be coupled with such existing quality adaptation mechanisms to derive better results, driven also by the preferences of the user. Head‐tracking data, captured from camera feeds available at the user side, is an example of such data to which Recurrent Attention Models could be applied to accurately predict the focus of attention of users within videos frames. Information obtained from such models could be used to assist a preemptive buffering approach of specific viewing angles, contributing to the joint goal of maximising QoE. Based on these assumptions, a research line is presented, focusing on obtaining better QoE in an already existing multi‐view streaming system
300 GHz quadrature phase shift keying and QAM16 56 Gbps wireless data links using silicon photonics photodiodes
Authors: Belem‐Goncalves C. , Lacombe E. , Gidel V. , Durand C. , Gianesello F. , Gloria D. , Luxey C. , Ducournau G.
Published: May 2019

In this Letter, the authors report the achievement of terahertz transmissions using advanced quadrature amplitude modulation (QAM)16 signals using 300 GHz silicon photonics devices, developed in industrial foundry process PIC25G. Up to 56 Gbps is obtained using QAM16 single channel modulation and up to 50 Gbps in a dual‐channel configuration.
Wideband polarisation‐insensitive metasurface with tunable near‐field scattering focusing characteristic
Authors: Lv Yan‐He , Ding Xiao , Wang Bing‐Zhong , Wang Ren
Published: May 2019

A wideband polarisation‐insensitive metasurface (MS) has been proposed for tunable near‐field scattering focusing. The MS is composed of dual‐polarised unit cells with tunable reflection phases covering a range of 360°. Designed with the optical path method, the proposed MS demonstrates precise tunable and polarisation‐insensitive near‐field focusing in a wide band from 11 to 13 GHz in both simulation and experimental results.
Non‐isolated resonant quasi‐Z‐source network DC–DC converter
Authors: Adamowicz M.
Published: May 2019

A novel non‐isolated resonant quasi‐impedance (quasi‐Z)‐source network DC–DC converter is proposed. The resonant impedance source network is derived from the quasi‐Z‐source network by including the autotransformer‐based resonant cell instead of the second inductor of the quasi‐Z‐network. The leakage inductance of the autotransformer and two resonant capacitors connected in series with the autotransformer windings constitute a high‐frequency resonant tank. At the same time, the resonant capacitors block the DC‐bias current of the autotransformer. The resonant operation with a sinusoidal current of the main switch and diodes enables electromagnetic interference mitigation and improves the efficiency of the converter. Experimental results of a 100 W, 30 V/200 V prototype are presented to verify the analysis results of the proposed converter.
Low‐loss and ultra‐wide passband highpass filter using suspended integrated strip‐line technology
Authors: McDaniel J.W. , Sigmarsson H.H.
Published: May 2019

This Letter presents a low‐loss highpass filter (HPF) with an ultra‐wide passband using the suspended integrated strip‐line (SISL) technology. The HPF is an 11th‐order generalised Chebyshev design with a cutoff frequency of 2 GHz and a passband that extends up to 18 GHz. Measured results show of insertion loss across the 16 GHz passband and of suppression below 1.5 GHz. The proposed fully board embedded SISL HPF also has advantages of compact size, light‐weight, and low cost following the trend to reduce the size, weight, power, and cost.
Modelling of reduced electromechanical interaction system for aircraft applications
Authors: Ahumada Constanza , Wheeler Pat
Published: May 2019

Rotational systems such as aircraft engine drivetrains are subject to vibrations that can damage shafts. Torsional vibrations in drivetrains can be excited by the connection of loads to the generator due to electromechanical interaction. This problem is particularly relevant in new aircraft because the drivetrain is flexible and the electrical power system (EPS) load is high. To extend the lifespan of the aircraft engine, the electromechanical interaction must be considered. Since real‐time constants of the electrical and mechanical systems have very different magnitudes, the simulation time can be high. Furthermore, highly detailed models of the electrical system have unnecessary complexity for the study of electromechanical interactions. For these reasons, modelling using reduced order systems is fundamental. Past studies of electromechanical interaction in aircraft engines developed models that allow the analysis of the torsional vibration, but these are difficult to implement. In this study, a reduced order electromechanical interaction system for aircraft applications is proposed and validated using experimental results. The proposed system uses a reduced drivetrain, simplified EPS, and sensorless measurement of the vibrations. The excitation of torsional vibrations obtained is compared with past studies to prove that the reduced order system is valid for studying the electromechanical interactions.
Extension of the HCOOH and CO2 solid-state reaction network during the CO freeze-out stage: inclusion of H2CO
Authors: Qasim D. , Lamberts T. , He J. , Chuang K.-J. , Fedoseev G. , Ioppolo S. , Boogert A. C. A. , Linnartz H.
Published: May 2019

Context. Formic acid (HCOOH) and carbon dioxide (CO2) are simple species that have been detected in the interstellar medium. The solid-state formation pathways of these species under experimental conditions relevant to prestellar cores are primarily based off of weak infrared transitions of the HOCO complex and usually pertain to the H2O-rich ice phase, and therefore more experimental data are desired.

Aims. Here, we present a new and additional solid-state reaction pathway that can form HCOOH and CO2 ice at 10 K “non-energetically” in the laboratory under conditions related to the “heavy” CO freeze-out stage in dense interstellar clouds, i.e., by the hydrogenation of an H2CO:O2 ice mixture. This pathway is used to piece together the HCOOH and CO2 formation routes when H2CO or CO reacts with H and OH radicals.

Methods. Temperature programmed desorption – quadrupole mass spectrometry (TPD-QMS) is used to confirm the formation and pathways of newly synthesized ice species as well as to provide information on relative molecular abundances. Reflection absorption infrared spectroscopy (RAIRS) is additionally employed to characterize reaction products and determine relative molecular abundances.

Results. We find that for the conditions investigated in conjunction with theoretical results from the literature, H + HOCO and HCO + OH lead to the formation of HCOOH ice in our experiments. Which reaction is more dominant can be determined if the H + HOCO branching ratio is more constrained by computational simulations, as the HCOOH:CO2 abundance ratio is experimentally measured to be around 1.8:1. H + HOCO is more likely than OH + CO (without HOCO formation) to form CO2. Isotope experiments presented here further validate that H + HOCO is the dominant route for HCOOH ice formation in a CO-rich CO:O2 ice mixture that is hydrogenated. These data will help in the search and positive identification of HCOOH ice in prestellar cores.
Multiwavelength analysis of brightness variations of 3C 279: probing the relativistic jet structure and its evolution
Authors: Beaklini Pedro P. B. , Dominici Tânia P. , Abraham Zulema , Motter Juliana C.
Published: May 2019

Aims. We studied the correlation between brightness and polarization variations in 3C 279 at different wavelengths, over time intervals long enough to cover the time lags due to opacity effects. We used these correlations together with VLBI images to constrain the radio and high energy source position.

Methods. We made 7 mm radio continuum and R-band polarimetric observations of 3C 279 between 2009 and 2014. The radio observations were performed at the Itapetinga Radio Observatory, while the polarimetric data were obtained at Pico dos Dias Observatory, both in Brazil. We compared our observations with the γ-ray Fermi/LAT and R-band SMARTS light curves.

Results. We found a good correlation between 7 mm and R-band light curves, with a delay of 170 ± 30 days in radio, but no correlation with the γ rays. However, a group of several γ-ray flares in April 2011 could be associated with the start of the 7 mm strong activity observed at the end of 2011. We also detected an increase in R-band polarization degree and rotation of the polarization angle simultaneous with these flares. Contemporaneous VLBI images at the same radio frequency show two new strong components close to the core, ejected in directions very different from that of the jet.

Conclusions. The good correlation between radio and R-band variability suggests that their origin is synchrotron radiation. The lack of correlation with γ-rays produced by the Inverse Compton process on some occasions could be due to the lack of low energy photons in the jet direction or to absorption of the high energy photons by the broad line region clouds. The variability of the polarization parameters during flares can be easily explained by the combination of the jet polarization parameters and those of newly formed jet components.
A massive nebula around the luminous blue variable star RMC 143 revealed by ALMA
Authors: Agliozzo C. , Mehner A. , Phillips N. M. , Leto P. , Groh J. H. , Noriega-Crespo A. , Buemi C. , Cavallaro F. , Cerrigone L. , Ingallinera A. , Paladini R. , Pignata G. , Trigilio C. , Umana G.
Published: May 2019

The luminous blue variable (LBV) RMC 143 is located in the outskirts of the 30 Doradus complex, a region rich with interstellar material and hot luminous stars. We report the 3σ sub-millimetre detection of its circumstellar nebula with ALMA. The observed morphology in the sub-millimetre is different than previously observed with HST and ATCA in the optical and centimetre wavelength regimes. The spectral energy distribution (SED) of RMC 143 suggests that two emission mechanisms contribute to the sub-mm emission: optically thin bremsstrahlung and dust. Both the extinction map and the SED are consistent with a dusty massive nebula with a dust mass of 0.055 ± 0.018 M⊙ (assuming κ850 = 1.7 cm2 g−1). To date, RMC 143 has the most dusty LBV nebula observed in the Magellanic Clouds. We have also re-examined the LBV classification of RMC 143 based on VLT/X-shooter spectra obtained in 2015/16 and a review of the publication record. The radiative transfer code CMFGEN is used to derive its fundamental stellar parameters. We find an effective temperature of ∼8500 K, luminosity of log(L/L⊙) = 5.32, and a relatively high mass-loss rate of 1.0 × 10−5 M⊙ yr−1. The luminosity is much lower than previously thought, which implies that the current stellar mass of ∼8 M⊙ is comparable to its nebular mass of ∼5.5 M⊙ (from an assumed gas-to-dust ratio of 100), suggesting that the star has lost a large fraction of its initial mass in past LBV eruptions or binary interactions. While the star may have been hotter in the past, it is currently not hot enough to ionize its circumstellar nebula. We propose that the nebula is ionized externally by the hot stars in the 30 Doradus star-forming region.
Protective effect ofGlycyrrhiza glabraroots extract on bone mineral density of ovariectomized rats
Authors: Galanis Dimitrios , Soultanis Konstantinos , Lelovas Pavlos , Zervas Alexandros , Papadopoulos Panagiotis , Galanos Antonis , Argyropoulou Katerina , Makropoulou Maria , Patsaki Anastasia , Passali Christina , Tsingotjidou Anastasia , Kourkoulis Stavros , Mitakou Sofia , Dontas Ismene
Published: May 2019

Objective: The aim of this study was to evaluate the potential effect of the methanolic extract of plantGlycyrrhiza glabraroots on bone mineral density and femoral bone strength of ovariectomized rats.

Methods: Thirty 10-month-old Wistar rats were randomly separated into three groups of ten, Control, Ovariectomy and Ovariectomy-plus-Glycyrrhiza in their drinking water. Total and proximal tibial bone mineral density was measured in all groups before ovariectomy (baseline) and after 3 and 6 months post ovariectomy. Three-point-bending of the femurs and uterine weight and histology were examined at the end of the study.

Results: No significant difference was noted in bone density percentage change of total tibia from baseline to 3 months between Control and Ovariectomy-plus-Glycyrrhiza groups (+5.31% ± 4.75 and +3.30% ± 6.31 respectively,P = non significant), and of proximal tibia accordingly (+5.58% ± 6.92 and +2.61% ± 13.62,P = non significant) demonstrating a strong osteoprotective effect. There was notable difference in percentage change of total tibia from baseline to 6 months between groups Ovariectomy and Ovariectomy-plus-Glycyrrhiza (−13.03% ± 5.11 and −0.84% ± 7.63 respectively,P < 0.005), and of proximal tibia accordingly (−27.9% ± 3.69 and −0.81% ± 14.85 respectively,P < 0.001), confirming the protective effect ofGlycyrrhiza glabraextract in preserving bone density of the Ovariectomy-plus-Glycyrrhiza group. Three-point-bending did not reveal any statistically significant difference between Ovariectomy and Ovariectomy-plus-Glycyrrhiza groups. Uterine weights of the Ovariectomy-plus-Glycyrrhiza group ranged between the other two groups with no statistically significant difference to each.

Conclusions:Glycyrrhiza glabraroot extract notably protected tibial bone mineral density loss in Ovariectomy-plus-Glycyrrhiza rats in comparison with ovariectomized rats, but did not improve biomechanical strength.
Fermentation du poisson en Afrique de l’Ouest et défis sociétaux pour une amélioration qualitative des produits (adjuevan,guedjetlanhouin) : revue de la littérature
Authors: Fall Moussou , Diop Michel Bakar , Montet Didier , Maiga Amadou Seidou , Guiro Amadou Tidiane
Published: May 2019

Le poisson est la principale source de protéines animales dans les zones côtières de l’Afrique de l’Ouest, notamment au Bénin, en Côte d’Ivoire et au Sénégal. Le problème de la conservation des produits halieutiques débarqués est un défi sociétal majeur dans ces pays du fait de l’insuffisance d’infrastructures industrielles. La transformation alimentaire traditionnelle contribue à la réduction des pertes post-capture. Divers produits transformés locaux comme l’adjuevan(Côte d’Ivoire), lelanhouin(Bénin) et leguedj(Sénégal), dont les procédés incluent le salage, la fermentation et le séchage, sont proposés aux consommateurs. Ils sont généralement utilisés comme condiments ou parfois comme sources majeures de protéines animales pour enrichir les apports nutritionnels des aliments à base de céréales locales. Les technologies traditionnelles employées pour ces produits sont peu coûteuses, du fait des équipements rudimentaires utilisés. La non-standardisation des techniques de production, notamment la fermentation, généralement spontanée, contribue à une qualité très fluctuante. Cette synthèse présente les différentes approches de fermentation conduisant aux divers produits ciblés, les caractéristiques physico-chimiques et microbiologiques de ces produits, les initiatives d’amélioration essentiellement basées sur le recours à des ferments et les défis sociétaux (renforcement de la recherche, formation des acteurs locaux, appui à la commercialisation) pour la croissance économique de ce secteur.
Monitoring aquatic plants: An evaluation of hydroacoustic, on-site digitising and airborne remote sensing techniques
Authors: Stocks Jerom R. , Rodgers Michael P. , Pera Joe B. , Gilligan Dean M.
Published: May 2019

Aquatic macrophytes are often monitored to detect change in ecosystem function and state, as well as assessing the effectiveness of invasive aquatic plant management. This study compares seven methodologies to monitor the distribution and abundances of aquatic macrophytes. Four line transect methodologies and three spatial mapping techniques were employed in parallel over a broad turbidity gradient in two lentic habitats of south-eastern Australia. The methodologies examined included hydroacoustic surveys, on-site digitising, and digitisation of airborne remote sensing imagery. Variation in estimates of macrophyte coverage were observed between methodologies. Consistency in the collection and interpretation of data was greatest for the line transect methodologies and the digitisation of satellite imagery. Duel-frequency identification sonar proved to be an effective novel hydroacoustic technique to monitor macrophyte abundances over broad spatial scales. Single beam sonar transects was also an objective, repeatable and scalable methodology. Videography and on-site handheld PDA mapping were of limited utility due to restrictions imposed by turbidity. The utility of sidescan sonar could be improved when used in conjunction with on-site handheld PDA mapping. This study outlines important considerations when selecting a methodology to monitor macrophyte distribution and abundance. Results indicate that no one specific method can be employed across all macrophyte monitoring studies. The method or combination of methods employed during macrophyte monitoring studies is dependent upon the study objectives, budget and environmental conditions of the study site.
Indoor hazards management using digital technology
Authors: Wehbe Rania , Shahrour Isam
Published: May 2019

Management of indoor hazards constitutes a great challenge for buildings design, construction and operating. The question is how to reduce both buildings vulnerability to indoor hazards and the impact of the latter on occupants and buildings integrity. Indoor hazards could result from different source such as fire, air pollution, water and gas leak, domestic accidents, appliances hazards, intrusion and break-out. Standards are already established for safety buildings design. However, in the operating phase, both occupants and buildings managers are subjected to serious indoor hazards, which could lead to significant human and material damages. The development of the digital technology such as Internet of Things (IoT), communication technology, indoor smart monitoring and Building Information Modeling (BIM) offers a great opportunity to improve indoor safety. This paper presents the indoor hazards and how the smart technology could help in improving the indoor hazard management.