bluuebunny/crossref_metadata_2025 huggingface dataset:
Be Sustainable to Be Innovative: An Analysis of Their Mutual Reinforcement
Authors: Behnam Sarah , Cagliano Raffaella
Published: December 2016

Sustainable development has attracted the increasing attention of both researchers and practitioners. While academicians and practitioners’ focus towards sustainability has shifted to innovation, there is a need to understand how sustainability and innovation are interlinked. Thus, this paper attempts to analyze, first, the bidirectional impact of the firms’ pursuit of sustainability and innovation as the priority, second, the bidirectional impact of the adoption of sustainability innovation action programs and, third, to discern the bidirectional influence of sustainability and innovation performances. The evidence is drawn from a sample of 860 manufacturing plants in 22 countries from the sixth edition of the International Manufacturing Strategy Survey 2013. The survey was conducted using a self-administered questionnaire. Structural equation modelling has been employed to test the model. The results show that sustainability and innovation positively and significantly impact each other in terms of the adoption of their relevant action programs and performance. However, the pursuit of sustainability priority acts as an antecedent of innovation priority.
Bouncing Cosmologies with Dark Matter and Dark Energy
Authors: Cai Yi-Fu , Marcianò Antonino , Wang Dong-Gang , Wilson-Ewing Edward
Published: December 2016

We review matter bounce scenarios where the matter content is dark matter and dark energy. These cosmologies predict a nearly scale-invariant power spectrum with a slightly red tilt for scalar perturbations and a small tensor-to-scalar ratio. Importantly, these models predict a positive running of the scalar index, contrary to the predictions of the simplest inflationary and ekpyrotic models, and hence, could potentially be falsified by future observations. We also review how bouncing cosmological space-times can arise in theories where either the Einstein equations are modified or where matter fields that violate the null energy condition are included.
Effect of Minor Populations of NS5A and NS5B Resistance-Associated Variants on HCV Genotype-3 Response to Daclatasvir plus Sofosbuvir, with or without Ribavirin
Authors: McPhee Fiona , Hernandez Dennis , Zhou Nannan
Published: December 2016

Background

Treatment of hepatitis C virus (HCV) genotype 3 (GT3) is a medical priority. All-oral treatment of HCV GT3 with daclatasvir (DCV) and sofosbuvir (SOF), with or without ribavirin (RBV), is recommended by several treatment guidelines. The impact of HCV minority populations at amino acid positions in NS5A and NS5B associated with drug resistance on response to DCV+SOF±RBV was assessed in SOF-naive and SOF-experienced HCV patients.

Methods

The presence of baseline NS5A or NS5B polymorphisms was assessed in 227 and 167 HCV-GT3-infected patients, respectively, from four clinical studies of DCV+SOF±RBV. Polymorphisms were identified at a sequencing detection threshold of ≥10%, and at ≥1% by next-generation sequencing (NGS) for a subset.

Results

No SOF resistance-associated polymorphisms were detected at baseline. Among 58 patients with prospective baseline sequencing data at ≥10% and ≥1%, detectable NS5A substitutions at A30 (A30K/R/S/T/V), S62 (S62A/F/K/L/T) or Y93H were 38% more prevalent at ≥1% compared with ≥10% (55% [32/58] versus 41% [24/58] of patients), although sustained virological response (SVR) in patients with these substitutions remained the same at both sequencing thresholds (88%). Only one additional Y93H was detected at ≥1%; the patient achieved SVR. In two virological failures with baseline Y93H, a minority S62L substitution at baseline was enriched from <20% to ≥95% at failure. Treatment-emergent minority populations (at A30, L31, P32, P58 and E92) observed by NGS in four virological failures became undetectable by week 24 post-treatment.

Conclusions

Sequencing at a depth of ≥10% appears to be sufficient to predict HCV GT3 response to DCV+SOF±RBV.
Le Prince d’Albert Memmi, une tentative théâtrale sur le pouvoir et la domination
Authors: Sanson Hervé
Published: December 2016

Le Prince d’Albert Memmi est la seule tentative d’écriture théâtrale jamais tentée par l’écrivain et sociologue franco-tunisien à ce jour, et encore inédite. Dans cette ébauche, les principales problématiques ayant nourri l’œuvre de Memmi sont présentes : les rapports de domination, tout d’abord, ceux de classe, mais aussi les rapports de genres, et donc l’oppression féminine. Cet essai théâtral offre également une réflexion sur la nature du pouvoir, thématique centrale dans le roman Le Désert qui lui est contemporain. L’étude du dossier génétique propose enfin une perspective fort intéressante sur ce que doit être l’œuvre théâtrale, et sa dimension visuelle, première selon Memmi.
Copy Editing of the Journal Articles
Authors: Mahaliyanaarachchi Rohana P
Published: December 2016

Here I would like make your attention to the importance of copy editing of articles before publishing in a journal. Copy editing can be done by author himself or by the editorial office of the journal for accepted articles for publication. Copy editing is a process that guarantees that the text of the article is correct in terms of grammar, spelling, punctuations, terminology, and formatting. It is also a role of copy editors to ensure the flow of the article and make sure it is sensible and readable. They are also responsible for adding headers, headlines, banners, footnotes and other improvements for the article wherever necessary.Copy editors require a number of skills such as excellent command of the language, ability to identify inconsistencies of the article and should be able to identify factual errors. Sometimes, even though the quality of study is high, language deficiencies occur due to language barriers of non-native writers.  Standard copy-editing of an article helps international researchers to eliminate language barriers and accept their work and publish in prestigious international journals. Therefore, it is an important requirement in today’s publishing business to copy edit ensure the quality of the article, book or any other piece of writing.From this volume, the Journal of Agricultural Sciences seriously consider of copy editing and all the papers published in this issue are copy edited by a professional copy editor. Our effort is to produce the highest quality journal in the field of agricultural sciences by ensuring all the quality aspects of a prestigious journal. While we are not looking towards gaining any financial benefit via the publishing of this journal, we must appreciate the support given by the top administration of the Sabaragamuwa University of Sri Lanka in publishing this journal by providing substantial funds.At present, the JAS has been included in more than 35 journal databases including AGRICOLA, AGORA, Cabi Abstracts, TEEL and DOAJ. It depicts the wider acceptance of JAS by international citations and journal databases. This is an indicator for our progress in the quality of our journal during past years. There were many personages behind this success. Accordingly, the honour of this success effort must go to Dr. Chandrika Dissanayake - Coordinating Editor of JAS, Mr Prasad C. Iddamalgoda, Mr. Udesh Gayan Kumara, Ms Suiox Cummings and Andy Nobes of SLJOL, all the authors, reviewers and also the members of the Editorial Committee.
HTLV-1 Tax-Specific CTL Epitope–Pulsed Dendritic Cell Therapy Reduces Proviral Load in Infected Rats with Immune Tolerance against Tax
Authors: Ando Satomi , Hasegawa Atsuhiko , Murakami Yuji , Zeng Na , Takatsuka Natsuko , Maeda Yasuhiro , Masuda Takao , Suehiro Youko , Kannagi Mari
Published: December 2016

Adult T cell leukemia/lymphoma (ATL), a CD4+ T cell malignancy with a poor prognosis, is caused by human T cell leukemia virus type 1 (HTLV-1) infection. High proviral load (PVL) is a risk factor for the progression to ATL. We previously reported that some asymptomatic carriers had severely reduced functions of CTLs against HTLV-1 Tax, the major target Ag. Furthermore, the CTL responses tended to be inversely correlated with PVL, suggesting that weak HTLV-1–specific CTL responses may be involved in the elevation of PVL. Our previous animal studies indicated that oral HTLV-1 infection, the major route of infection, caused persistent infection with higher PVL in rats compared with other routes. In this study, we found that Tax-specific CD8+ T cells were present, but not functional, in orally infected rats as observed in some human asymptomatic carriers. Even in the infected rats with immune unresponsiveness against Tax, Tax-specific CTL epitope–pulsed dendritic cell (DC) therapy reduced the PVL and induced Tax-specific CD8+ T cells capable of proliferating and producing IFN-γ. Furthermore, we found that monocyte-derived DCs from most infected individuals still had the capacity to stimulate CMV-specific autologous CTLs in vitro, indicating that DC therapy may be applicable to most infected individuals. These data suggest that peptide-pulsed DC immunotherapy will be useful to induce functional HTLV-1–specific CTLs and decrease PVL in infected individuals with high PVL and impaired HTLV-1–specific CTL responses, thereby reducing the risk of the development of ATL.
Multicentre Evaluation of the Naída CI Q70 Sound Processor: Feedback from Cochlear Implant Users and Professionals
Authors: Martin Jeanette , Poncet-Wallet Christine , Illg Angelika , Perrin-Webb Sarah , Henderson Lise , Noël-Petroff Nathalie , Auletta Gennaro , Barezzani Maria Grazia , Houri Karim , Indian Research Group  , Bagus Heike , Hoppe Ulrich , Humphries Jane , van Treeck Wiebke , Briaire Jeroen J. , Brendel Martina , Mathias Nathalie
Published: December 2016

The aim of this survey was to gather data from both implant recipients and professionals on the ease of use of the Naída CI Q70 (Naída CI) sound processor from Advanced Bionics and on the usefulness of the new functions and features available. A secondary objective was to investigate fitting practices with the new processor. A comprehensive user satisfaction survey was conducted in a total of 186 subjects from 24 centres. In parallel, 23 professional questionnaires were collected from 11 centres. Overall, there was high satisfaction with the Naída CI processor from adults, children, experienced and new CI users as well as from professionals. The Naída CI processor was shown as being easy to use by all ages of recipients and by professionals. The majority of experienced CI users rated the Naída CI processor as being similar or better than their previous processor in all areas surveyed. The Naída CI was recommended by the professionals for fitting in all populations. Features like UltraZoom, ZoomControl and DuoPhone would not be fitted to very young children in contrast to adults. Positive ratings were obtained for ease of use, comfort and usefulness of the new functions and features of the Naída CI sound processor. Seventy-seven percent of the experienced CI users rated the new processor as being better than their previous sound processor from a general point of view. The survey also showed that fitting practices were influenced by the age of the user.
What influences treatment satisfaction in patients with personality disorders? A naturalistic investigation in a hospitalization setting
Authors: Gebhardt Stefan , Huber Martin Tobias
Published: December 2016

Treatment satisfaction of different mental disorders is still poorly understood, but of high clinical interest. Inpatients of a general psychiatric care hospital were asked to fill out questionnaires on satisfaction at discharge and clinical variables at admission and discharge were assessed. On the basis of an exploratory approach, differences in treatment satisfaction among diagnostic groups were examined by means of one-way analysis of variance. Potential associated clinical and socio-demographic variables were studied using multi/univariate tests. Patients with personality disorders (n=18) showed a significantly lower treatment satisfaction (ZUF-8, Zurich Satisfaction Questionnaire) and a slightly lower improvement of symptoms (CGI, Clinical Global Impression) and global functioning (GAF, Global Assessment of Functioning scale) than that of other diagnostic groups (n=95). Satisfaction in patients with personality disorders correlated much stronger with the symptom improvement and slightly with the functioning level than in patients without personality disorders. Interestingly, in patients with personality disorders psychopharmacological treatment in general (present versus not present) was independent from satisfaction. This exploratory investigation suggests that a lower satisfaction of patients with personality disorders in a general psychiatric hospital is mainly based on a reduced improvement of the symptoms and of the global functioning level.
Anatomicosurgical References for Endoscopic Localization of Sphenopalatine Foramen: A Cadaveric Study
Authors: Gupta Ashok , Sahni Daisy , Gupta Tulika , Aggarwal Anjali
Published: December 2016

Introduction

In patients with posterior epistaxis, generally the source of bleeding is branches of sphenopalatine artery (SPA), which enter the nasal cavity through the sphenopalatine foramen (SPF). Cases of intractable massive bleeding may require endonasal endoscopic occlusion of these vessels.

Materials and methods

A total of 32 hemisections of formalinfixed cadaveric heads were used. The anatomic variations of SPF, its distance from anatomical landmarks, and angle of elevation of endoscope were studied so as to facilitate accurate localization of the foramen and endoscopic arterial ligation.

Results

The SPF was generally single; however, multiple exits in the form of accessory foramina were found in 36.75% hemisections. The transition of superior and middle meatuses was the most common location of SPF, followed by the superior meatus, and middle meatus was the least common site. The accessory foramina were commonly present in the superior meatus. Ethmoid crest was distinctly visible in all but two cases. In majority of the cases, the SPF was located within a range of 55 to 65 mm from the anterior nasal spine (ANS); 60 to 70 mm from piriform aperture, 50 to 60 mm from limen nasi, 20.1 to 25 mm vertically above the floor of nasal cavity, and 8 to 15 mm from the inferior turbinate (IT). The angulation of SPF from the floor of nasal cavity was 20 to 30°.

Conclusion

Exploration of lateral nasal wall (LNW) up to middle meatus would minimize the risk of missing any arterial branch, and the data of distance from the anatomical references would assist in more precise localization of SPF during endoscopic ligation or cauterization of the branches of the SPA.

How to cite this article

Aggarwal A, Gupta T, Sahni D, Gupta A. Anatomicosurgical References for Endoscopic Localization of Sphenopalatine Foramen: A Cadaveric Study. Clin Rhinol An Int J 2016;9(3):109-114.
Isolated Abducens Nerve Palsy Secondary to Isolated Sphenoid Sinus Disease: Case Series
Authors: Harugop Anilkumar Suryadev , Mudhol Ramesh S , Bellad Shama A , Hajare Priti S , Kaku Dharmishtha R , Hiremath Basavaraj
Published: December 2016

Isolated sphenoid sinusitis is a rare entity. Due to noncharacteristic primary manifestations, most of the patients present with ophthalmic complications, most commonly proptosis and diplopia. We report here the case series of two patients who presented with diplopia, blurred vision, and headache. Diagnosis of isolated abducens nerve palsy secondary to isolated sphenoid sinus disease was made, and both the patients underwent endoscopic sinus surgery (ESS). We hereby propose that prompt diagnosis and treatment of isolated sphenoidal sinusitis is very important, and abducens nerve (CN6) palsy could be attributed to the disease condition as both the patients’ condition improved after surgery.

How to cite this article

Harugop AS, Mudhol RS, Bellad SA, Hajare PS, Kaku DR, Hiremath B. Isolated Abducens Nerve Palsy Secondary to Isolated Sphenoid Sinus Disease: Case Series. Clin Rhinol An Int J 2016;9(3):137-140.
Pleomorphic Adenoma of the Lateral Nasal Wall: An Unusual Entity
Authors: Bhardwaj Aparna , Rathi Sonam
Published: December 2016

Pleomorphic adenomas occurring in the nasal cavity are rarely encountered; nevertheless, there is abundance of minor seromucinous glands in that region. Most cases present with a painless, slowly progressing unilateral nasal obstruction, a nasal mass, and epistaxis. Herewith, we present an unusual case of pleomorphic adenoma arising from the lateral wall of the right nasal cavity in a 41-year-old male who complained of right nasal obstruction with no history of epistaxis. Rigid nasal endoscopy revealed a swelling continuous with right inferior concha. Computed tomography showed a well-defined, soft tissue mass in the right nasal cavity. The lesion was completely excised endoscopically. Histopathology confirmed a pleomorphic adenoma consisting of epithelial and mesenchymal elements. Wide exposure is crucial for complete excision with negative margins to achieve positive outcome and to prevent recurrence.

How to cite this article

Pandey AK, Bhardwaj A, Maithani T, Rathi S. Pleomorphic Adenoma of the Lateral Nasal Wall: An Unusual Entity. Clin Rhinol An Int J 2016;9(3):146-148.
An Unusual ENT Presentation of Retinoblastoma: A Diagnostic Dilemma
Authors: Saha Subhasis , Das Saumik , Jana Tamoghna , Sengupta Moushumi , Saha Asok K
Published: December 2016

Retinoblastoma is the most common intraocular tumor of childhood. These tumors, though they respond to treatment, are prone to develop secondary malignancy, recurrence, and metastasis, which may present as sinonasal mass. We are presenting a rare case of metastatic retinoblastoma of sinonasal region in a 3-year-old male child. The mode of presentation and management of the case is presented along with a review of the literature.

How to cite this article

Jana T, Sengupta M, Das S, Saha AK, Saha S. An Unusual ENT Presentation of Retinoblastoma: A Diagnostic Dilemma. Clin Rhinol An Int J 2016;9(3):149-152.
Touching Greater Horizons in the Management of Diabetic Neuropathy: Epalrestat in Advanced Role
Authors: Maladkar Manish , Tekchandani Chitra , Siddhanti Aakash
Published: December 2016

The major factor contributing to the pathogenesis of type 2 diabetes and its various complications is insulin resistance (IR). The lesser known and interesting element that has been unfolding is about the existence of IR in neurons associated with disrupted phosphatidylinositol 3-kinase/protein kinase B (PI3k/Akt) pathway with subsequent adverse effect on nerve function. Hyperactivity of polyol pathway is identified as the prime convincing mechanism elucidating the metabolic link between hyperglycemia and nerve dysfunction. Additionally, in the polyol trail, reduction in glutathione leads to redox imbalance and eventually neuropathy.

Epalrestat, the aldose reductase inhibitor (ARI), has been extensively evaluated for its efficacy and safety in the treatment of diabetic neuropathy. Addition of methylcobalamin to Epalrestat therapy has shown faster and better resolution of neuropathy. Epalrestat-induced activation of PI3k/Akt signaling pathway promotes proliferation and migration of endothelial cells, with potential benefits of improved blood supply to damaged nerves. Further evidences reveal upregulation of nerve growth factor (NGF) by Epalrestat that has resulted in wound healing in diabetic patients. Increase in nerve fiber length is the other compatible finding with Epalrestat therapy in patients suffering from diabetic neuropathy. Moreover, Epalrestat has demonstrated significant protection against oxidative stress via induction of glutathione biosynthesis.

How to cite this article

Maladkar M, Tekchandani C, Siddhanti A. Touching Greater Horizons in the Management of Diabetic Neuropathy: Epalrestat in Advanced Role. J Med Sci 2016;2(1):9-14.
Money Demand in Rwanda: A Cointegration Analysis 2008Q3-2015Q4
Authors: Nkurunziza Fabrice
Published: December 2016

This paper estimates the demand for money in Rwanda over the 2008Q3 to 2015Q4 period via unit root and cointegration methods. Utilizing the Johansen cointegration methodology, it establishes that a long-term relationship exists among the included variables. The paper also estimates an error correction model (ECM) as well as a vector error correction model (VECM), extending previous analyses by testing for Granger causality among the variables. It finds that the narrow definition of money, M1, serves as a relatively better measure of the money aggregate than M2, and M3. The long-term interest rate (LKRR) also seems to provide relatively better results than the short-term rate (LRR, and LTR) when we use broad money definition, M2. Both the ECM and VECM for M1, narrow definition of money estimates showed the expected signs, in the ECM model as expected LM1 and LGDP were positively related while LM1 and LKRR, LRR, and LTR were negatively related. The adjustment coefficient in the ECM showed that about 79.75 % of disequilibrium is corrected in each quarter. Impulse response functions suggest that the traditional money demand function, which places LM1 as its ‘dependent’ variable while including income and interest rates as its regressors, was stable with little responses in the specific case of Rwanda over the period under review.
Reviewer Acknowledgements for International Journal of Culture and History, Vol. 3, No. 2
Authors: Johnson Bill
Published: December 2016

Reviewer Acknowledgements for International Journal of Culture and History, Vol. 3, No. 2, 2016
Assessing Local Cultural Heritage through a Walking Trail: The Case Study of the Theodoros Papagiannis’ Museum of Contemporary Art
Authors: Merantzas Christos
Published: December 2016

The paper focuses on the cultural components of a walking trail axed upon the ‘Theodoros Papagiannis’ collection of sculpture. The latter is hosted in the Museum of Contemporary Art of Helliniko, a village tucked within the Municipality of Northern Tzoumerka, Epirus, Greece. While the artist’s sculptures are also found in the Museum’s courtyard are they also admired along a walking trail that begins at the village’s entry point and ends at the Post-Byzantine Monastery of Tsouka. The research is carried out from the perspective of a walking trail’s cultural value. Our trail of interest joins two locations, the one being secular and the other sacred, thus defining an itinerary which unfolds along these two different attraction sites. As a result, the walker/traveler moves from one established location to the other, all the while objectifying the two and defining space under his/her own terms. He/She makes connections between both sites in order to restore the unity of space and thus becomes a travelling witness to the creation of a single narrative. He/She enjoys the privilege of the travelled route, as well as all that exists along this route.
Position Paper of the Italian Association of Medical Oncology on Early Palliative Care in Oncology Practice (Simultaneous Care)
Authors: Zagonel Vittorina , Franciosi Vittorio , Brunello Antonella , Biasco Guido , Broglia Chiara , Cattaneo Daniela , Cavanna Luigi , Corsi Domenico , Farina Gabriella , Fioretto Luisa , Gamucci Teresa , Lanzetta Gaetano , Magarotto Roberto , Maltoni Marco , Marchetti Paolo , Massa Elena , Mastromauro Cataldo , Melotti Barbara , Meriggi Fausto , Nacci Angelo , Pavese Ida , Piva Erico , Quirino Michela , Roselli Mario , Sacco Cosimo , Tonini Giuseppe , Trentin Leonardo , Ucci Giovanni , Labianca Roberto , Gori Stefania , Pinto Carmine , Cascinu Stefano ,   AIOM Simultaneous & Continuous Care (SCC), Task Force: ESMO Italian DCs
Published: December 2016

One of the priorities of personalized medicine regards the role of early integration of palliative care with cancer-directed treatments, called simultaneous care. This article, written by the Italian Association of Medical Oncology (AIOM) Simultaneous and Continuous Care Task Force, represents the position of Italian medical oncologists about simultaneous care, and is the result of a 2-step project: a Web-based survey among medical oncologists and a consensus conference. We present the opinion of more than 600 oncologists who helped formulate these recommendations. This document covers 4 main aspects of simultaneous care: 1) ethical, cultural, and relational aspects of cancer and implications for patient communication; 2) training of medical oncologists in palliative medicine; 3) research on the integration between cancer treatments and palliative care; and 4) organizational and management models for the realization of simultaneous care. The resulting recommendations highlight the role of skills and competence in palliative care along with implementation of adequate organizational models to accomplish simultaneous care, which is considered a high priority of AIOM in order to grant the best quality of life for cancer patients and their families.
Target Values in the History Course Curricula during the Republican Period
Authors: Ulusoy Kadir
Published: December 2016

No matter what the era is, history lesson is one of the leading of the courses that will provide the nations to comprehend the awareness of being a nation. For that reason, history education and teaching is permanently essential. History is the lesson that provide the nations to adapt the values they have, sustain these values through the awareness of protection and provide nations not to lose these, and help people understand the past and present. History has constantly protected its significance due to providing people to make inferences from the experiences, obtain some values, transfer the human values, and proving the negative behaviors such as injustice, malignancy, and wrong and positive behaviors such as justice, honesty, correct and goodness. For that reason, in this study, history lesson curriculums in Turkey were investigated in terms of the values, and the values required to be provided to the students in these programs were determined. Although the history lesson was taught through a program understanding without a specific purpose until 1971, some of these values were noticed to be provided during this period. Since 1971, it could be noticed that the values expected for the students to acquire have been included in purposes section of the history lesson in all history curriculums and program changes. National unity and solidarity is the leading of the values required to be provided, and the values related to a human model constitutional order aims to be raised has also been noticed to be included in all these curriculums.
¿Los alumnos quieren aprender con videojuegos? Lo que opinan sus usuarios del potencial educativo de este medio
Authors: Gómez-García Salvador , Planells de la Maza Antonio José , Chicharro-Merayo Mar
Published: December 2016

Los videojuegos han revelado su capacidad interactiva y su proximidad a los públicos juveniles. De ahí que se hayan convertido en una herramienta metodológica válida para vehicular contenidos docentes y muy valorada por expertos y educadores. Ahora bien, ¿qué opinan los alumnos de los videojuegos? ¿Qué relación mantienen con estos? ¿Qué capacidad educativa les conceden?En esta investigación realizamos, en primer lugar, un acercamiento a los principales argumentos académicos sobre el potencial educativo del videojuego. En segundo lugar, partiremos de la hipótesis de que los universitarios realizan un consumo lúdico y hedonista que se aleja de esta pretendida función docente. Desde ahí utilizaremos una metodología cualitativa (entrevista en profundidad) que aplicaremos a una muestra vinculada a la cultura audiovisual: estudiantes del grado de Comunicación Audiovisual, Medios Audiovisuales y Periodismo.Se pretende recoger los modelos discursivos del alumno que definen su relación extracurricular con el juego. En este sentido, la información recogida permite analizar variables como la «valoración del videojuego como recurso de aprendizaje», su «utilidad para el desarrollo de habilidades manuales e intelectuales» o «su rol en la motivación pedagógica», con un especial interés en las manifestaciones en función del género.
Horizontes educativos de los videojuegos. Propuestas y reflexiones de futuros maestros y educadores sociales
Authors: Correa García Ramon Ignacio , Duarte Hueros Ana , Guzmán Franco Mª Dolores
Published: December 2016

El videojuego concebido como juego electrónico en el que interactuar una o varias personas, y además hacerlo de forma tanto en línea como fuera de línea, es un instrumento que incluye diversos tipos de lenguajes, no solo el visual, sino también el sonoro, el literario, el gestual… todos ellos a elección del creador del mismo y de los usuarios. El carácter multilenguaje, junto con otras características como la interactividad, la digitalización, etc., los configura como una atractiva herramienta educativa con innumerables posibilidades formativas.Partiendo de la premisa de que la educación y la formación no pueden dar la espalda a la cultura y tecnología de su época, realizamos un estudio basado en una encuesta sobre los usos que hacen los futuros maestros, maestras y educadores sociales en formación de los videojuegos, su capacidad para integrarlos en el contexto educativo y la formación autopercibida para hacer un uso crítico y reflexivo de los mismos. De los resultados obtenidos se desprende que la mayoría de los participantes muestran una actitud muy favorable a la incorporación de los videojuegos en el ámbito educativo, si bien manifiestan presentar deficiencias en cuanto a su formación en competencias mediáticas para llevar a cabo una correcta integración curricular de los videojuegos.
Presentación
Authors: Marín-Díaz Verónica
Published: December 2016

Presentación del volumen 53/1.
Appendix to Sheehy article
Authors: Sheehy Helen M.
Published: December 2016

SyllabusLibrary Studies 397A: Introduction to Research in International Relations
Rare and Endangered Government Publications: Capturing the Moment
Authors: Quinn Aimée C. , Laster Shari
Published: December 2016

What are rare and endangered government publications? In short, they are the materials representing that which is valued most in our collections. Each depository library collects documents that are important to its community: some arrive through a depository program, some come through direct solicitation from agencies, some come through traditional means of acquisition, and some come through emerging models of building digital collections. Managing these resources to ensure their availability for long-term access is a critical part of government documents librarianship. Put another way, rare and endangered government publications are the pieces of the public output of government that are most likely to go missing.
125 Years: Serving the Government Information Needs of South Dakota
Authors: Mix Vickie
Published: December 2016

The year 1889 marked a territorial turning point for the nation. With the passage of the Enabling Act on February 22, 1889, territories in the wild, wild, west took to the statehood trail.
Review: The Indispensable Force: The Post-Cold War Operational Army Reserve, 1990-2010
Authors: Higbee Julie A.
Published: December 2016

The Indispensable Force, by Katherine Coker, offers a narrative history of the US Army Reserve in the 1990s and 2000s, when the Reserve transitioned from being a “strategic reserve,” deployed after the active duty army, to an “operational reserve,” frequently deployed along with the active army.
Editor's Corner
Authors: Psyck Elizabeth
Published: December 2016

THIS IS YOUR LAST PRINT ISSUE OF DOCUMENTS TO THE PEOPLE.Hopefully you’ve heard about this before now, but just in case you haven’t, rest assured that we have had a LOT of serious conversations about this change and the impact it will have on GODORT’s membership and DttP’s readership.
Editor’s Corner
Authors: Psyck Elizabeth
Published: December 2016

Hello, and welcome to our first online issue of DttP: Documents to the People!I’m writing this editor’s corner before the website is live, but I think it’s safe to say that we’re probably still working out the kinks and finding all the bugs in our new online home, so if you have any feedback, the publications committee and I would welcome it. (You can send me an email at psycke@gvsu.edu or dttp.editor@gmail.com—you know the drill.)
E-Book Cataloging Workflows at Oregon State University
Authors: Sapon-White Richard
Published: December 2016

Among the many issues associated with integrating e-books into library collections and services, the revision of existing workflows in cataloging units has received little attention. The experience designing new workflows for e-books at Oregon State University Libraries since 2008 is described in detail from the perspective of three different sources of e-books. These descriptions highlight where the workflows applied to each vendor’s stream differ. A workflow was developed for each vendor, based on the quality and source of available bibliographic records and the staff member performing the task. Involving cataloging staff as early as possible in the process of purchasing e-books from a new vendor ensures that a suitable workflow can be designed and implemented as soon as possible. This ensures that the representation of e-books in the library catalog is not delayed, increasing the likelihood that users will readily find and use these resources that the library has purchased.
Concepções e práticas no ensino de leitura em inglês no ensino médio
Authors: O'Connell Daniel Mateus , Monteiro Dirce Charara
Published: December 2016

Tendo em vista os resultados insatisfatórios no ensino de leitura em língua inglesa bem como a escassez de investigações sobre o tema no ensino médio, esta pesquisa tem como objetivo identificar as concepções teórico-metodológicas de duas professoras de Inglês desse nível de ensino sobre as diferentes abordagens de leitura e como essas concepções se fazem presentes em sua prática. Nesta pesquisa de natureza qualitativa os dados foram obtidos por meio da observação da prática docente e da realização de entrevistas com as professoras participantes. Os resultados da pesquisa poderão oferecer indicadores para ações voltadas para a melhoria do ensino da leitura em inglês como língua estrangeira
When and by whom are apologies considered? The effects of relationship and victim/observer standing on Japanese people’s forgiveness
Authors: Hashimoto Takaaki , Karasawa Kaori
Published: December 2016

Existing studies report on tendencies for first-party victims of a transgression to be less considerate of apologies compared to third-party observers when deciding on forgiveness. The present research investigated the conditions in which such discrepancies arise, focusing exclusively on the factor of one’s relational involvement with the transgressor. We presented Japanese participants (N = 116) with hypothetical cases of transgression, while varying on victim/observer standing, involvement with the transgressor, and the sincerity of presented apologies. As a result, the victim/observer discrepancy—where people who took the victim’s perspective rather than the observer’s perspective indicated decreased discrimination of the apology’s sincerity—emerged under high relational involvement. We further examined the role of trait evaluation of the transgressor as a mediator of the effect of apology on forgiveness. The test revealed that high involvement strengthens the mediation effect among the observers, while weakening the mediation among the victims. Based on the obtained findings, we discussed insights into how the relational factor facilitates different motives in victims and observers, leading to discrepancies in their reactions.
Scholarly Knowledge: At an Inflection Point?
Authors: Prewitt Kenneth
Published: December 2016

In the rapidly expanding sector of higher education worldwide, high quality research is disproportionately produced by a small number of research-intensive universities, probably no more than 400 worldwide. These universities are experiencing major changes, spurred by new technologies and data sources from those technologies, by the commercialization in the “knowledge economy” and competition from the for-profit private sector, and of course by opportunities and pressures of globalization itself. The phase we are in is further shaped by changes in how the state and the market set research priorities, partly by creating an accountability regime tied to timely and measurable contributions of products, services, and policies.Where does Africa fit in? It does not have competitive research-intensive universities. It does have high quality individual researchers. The author argues that its strength lies in robust regional research collaborations, coupled with serious engagement with stakeholder platforms including government, commerce, and NGOs.---Dans le secteur de l’enseignement supérieur mondial à l’expansion rapide, la recherche de grande qualité est produite disproportionnellement par un nombre restreint d’universités fortement axées sur la recherche, dont le nombre ne s’élève probablement pas à plus de 400 dans le monde entier. Ces universités sont en train de connaître des changements majeurs, déclenchés par les nouvelles technologies et les sources de données émanant de ces technologies, par la commer-cialisation dans l’ « économie du savoir » et la compétition provenant du secteur privé lucratif, et bien entendu, par des opportunités et des pressions créées par la mondialisation elle-même. La phase que nous traversons est, qui plus est, caractérisée par le changement de la manière dont l’état et le marché établissent les priorités de la recherche, partiellement en créant un régime où les instituions doivent rendre des comptes, un régime lié aux contributions opportunes et mesurables de produits, de services et de politiques.Dans ce contexte, où l’Afrique trouve-t-elle sa place ? Elle n’a pas d’universités compétitives axées fortement sur la recherche. Elle possède, néanmoins, des chercheurs individuels de grande qualité. L’auteur estime que sa force repose sur des partenariats de recherche régionaux solides, couplés à des engagements sérieux pris envers des parties prenantes comme le gouvernement, le milieu du commerce et les ONG.
Er ’klart sprog’ lettere at forstå? En undersøgelse af forståelsen af to versioner af et brev fra SKAT
Authors: Kjærgaard Anne , Jensen Torben Juel
Published: December 2016

I Danmark, såvel som i andre lande, har man i årtier forsøgt at gøre tekster fra offentlige myndigheder til almindelige borgere lettere at forstå for modtageren. Der mangler imidlertid empirisk belæg for at dette arbejde faktisk virker efter hensigten. I artiklen præsenteres en kvantitativ, eksperimentel undersøgelse af hvor godt læsere forstår to forskellige versioner af det samme brev fra SKAT – en oprindelig version som sprogmedarbejdere fra SKAT mente, var vanskelig at forstå, og en version der var omskrevet med henblik på at gøre brevet lettere at forstå. Det undersøges om den omskrevne version er lettere at forstå end den oprindelige, og hvordan faktorer som respondenternes uddannelse, alder, køn og læsefærdigheder påvirker forståelsen af teksterne. Analysen viser at den omskrevne version gennemsnitligt set er lettere at forstå end den oprindelige, og at uddannelse, læsefærdigheder, førstesprog og alder har betydning for forståelsen. Svage læsere har en betydeligt bedre forståelse af den omskrevne version end af den oprindelige, mens det for de bedste læsere i bedste fald ingen forskel gør for forståelsen hvilken version de læser. Artiklen afsluttes med en diskussion af hvilke elementer i den omskrevne version der tilsyneladende gør den lettere at forstå end den oprindelige.
Groundwater and civil protection, what the Italian for “hydrogeological risk” should mean
Authors: La Vigna Francesco
Published: December 2016

Not available.
Teleconnection between the South Atlantic convergence zone and the southern Indian Ocean: Implications for tropical cyclone activity
Authors: DeBlander Evan , Shaman Jeffrey
Published: December 2016

A link between anomalous austral summer convection over the South Atlantic convergence zone (SACZ) and atmospheric conditions over the South Indian Ocean is investigated. Interannual north‐south shifts in the SACZ produce a dipole of anomalous convection and precipitation over South America. The South Atlantic convergence zone index (SACZI) capturing this variability is presented and associated with a midlatitude Rossby wave train that propagates from South America eastward and south of Africa before curving north into the tropical Indian Ocean. This wave train is reproduced using Rossby wave ray tracing and simulations with a linearized barotropic vorticity equation model forced with divergence and convergence consistent with the observed dipole of anomalous convection. The wave train acts to excite anomalies in wind shear and relative humidity over the tropical south Indian Ocean, which in turn impact tropical cyclone (TC) genesis and distribution over this region. We find that changes in the wind shear and relative humidity associated with the SACZI effect changes in TC genesis, which result in a change in observed TC days over portions of the South Indian Ocean.
Nitrososphaera
Authors: Kerou Melina , Schleper Christa
Published: December 2016

Ni.tro.so.sphae'ra. N.L. adj.
nitrosus
full of natron; here intended to mean nitrous; L. fem. n.
sphaera
a ball, sphere; N.L. fem. n.
Nitrososphaera
the sphere producing nitrite.

Thaumarchaeota / Nitrososphaeria / Nitrososphaerales / Nitrososphaeraceae / Nitrososphaera

Characterized species of the genus
Nitrososphaera
are aerobic, neutrophilic and exhibit a chemolithoautotrophic metabolism, gaining energy by oxidizing ammonia to nitrite. Some species require supplementation with small organic acids (specifically α‐keto acids) for growth. Representatives of this genus are predominantly found in terrestrial ecosystems. The type species,
Nitrososphaera viennensis
, was the first pure isolate from a soil environment and the first described species of the class
Nitrososphaeria
. It is used as a model organism for physiological investigations of terrestrial ammonia oxidizers.

DNA G
+
C content (mol%)
: 48.4–52.7.

Type species
:
Nitrososphaera viennensis
Stieglmeier, Klingl, Alves, Rittmann, Melcher, Leisch and Schleper 2014b, 2746
VP
.
Pure erythroid leukemia
Authors: Wang Wei , Wang Sa A. , Medeiros L. Jeffrey , Khoury Joseph D.
Published: December 2016

The category of acute erythroid leukemia was significantly revised in the recently published 2016 revision to the World Health Organization (WHO) classification of myeloid neoplasms. In the previous 2008 WHO classification, acute erythroid leukemia was categorized into two subtypes: erythroleukemia and pure erythroid leukemia (PEL), whereas in the 2016 WHO update, erythroleukemia was merged into myelodysplastic syndrome, and PEL becomes the only type of acute erythroid leukemia. PEL is a rare and aggressive form of acute leukemia whose biology remains poorly characterized. In this review, we discuss the clinicopathologic features, diagnosis, putative pathogenesis, and molecular biology of PEL, with an overview of novel concepts and future directions in this area.
Lesions causing freezing of gait localize to a cerebellar functional network
Authors: Fasano Alfonso , Laganiere Simon E. , Lam Susy , Fox Michael D.
Published: December 2016

Objective

Freezing of gait is a disabling symptom in Parkinson disease and related disorders, but the brain regions involved in symptom generation remain unclear. Here we analyze brain lesions causing acute onset freezing of gait to identify regions causally involved in symptom generation.

Methods

Fourteen cases of lesion‐induced freezing of gait were identified from the literature, and lesions were mapped to a common brain atlas. Because lesion‐induced symptoms can come from sites connected to the lesion location, not just the lesion location itself, we also identified brain regions functionally connected to each lesion location. This technique, termed lesion network mapping, has been recently shown to identify regions involved in symptom generation across a variety of lesion‐induced disorders.

Results

Lesion location was heterogeneous, and no single region could be considered necessary for symptom generation. However, > 90% (13 of 14) of lesions were functionally connected to a focal area in the dorsal medial cerebellum. This cerebellar area overlapped previously recognized regions that are activated by locomotor tasks, termed the cerebellar locomotor region. Connectivity to this region was specific to lesions causing freezing of gait compared to lesions causing other movement disorders (hemichorea or asterixis).

Interpretation

Lesions causing freezing of gait are located within a common functional network characterized by connectivity to the cerebellar locomotor region. These results based on causal brain lesions complement prior neuroimaging studies in Parkinson disease patients, advancing our understanding of the brain regions involved in freezing of gait. ANN NEUROL 2017;81:129–141
An Optimal Control Approach to Linear Systems Controlled by Multiple Controllers
Authors: Yang Guoqing , Gao Zhenyu , Liu Zhongchang
Published: December 2016

This paper investigates the optimal control design methodology for linear systems which are collaboratively manipulated by multiple agents based on choices such that certain team targets are achieved. By minimizing the average energy cost subject to the set of specified target‐state constraints based on modern variation theory and the Lagrange method, a series of optimal control solutions are established for linear scalar and vector systems jointly controlled by two agents. In addition, a set of sub‐optimal controls are derived, which can lead to a tight upper bound on the average energy cost.
Tenocytic extract and mechanical stimulation in a tissue‐engineered tendon construct increases cellular proliferation and ECM deposition
Authors: Engebretson Brandon , Mussett Zachary R. , Sikavitsas Vassilios I.
Published: December 2016

Chemical and mechanical stimulation, when properly utilized, positively influence both the differentiation of in vitro cultured stem cells and the quality of the deposited extracellular matrix (ECM). This study aimed to find if cell‐free extract from primary tenocytes can positively affect the development of a tissue‐engineered tendon construct, consisting of a human umbilical vein (HUV) seeded with mesenchymal stem cells (MSCs) subjected to cyclical mechanical stimulation. The tenocytic cell‐free extract possesses biological material from tendon cells that could potentially influence MSC tenocytic differentiation and construct development. We demonstrate that the addition of tenocytic extract in statically cultured tendon constructs increases ECM deposition and tendon‐related gene expression of MSCs. The incorporation of mechanical stimulation (2% strain for 30 min/day at 0.5 cycles/min) with tenocytic extract further improved the MSC seeded HUV constructs by increasing cellularity of the construct by 37% and the ultimate tensile strength by 33% compared to the constructs with only mechanical stimulation after 14 days. Furthermore, the addition of mechanical stimulation to the extract supplementation produced longitudinal ECM fibril alignment along with dense connective tissue, reminiscent of natural tendon.