bluuebunny/crossref_metadata_2025 huggingface dataset:
A Recommendation Approach Using Forwarding Graph to Analyze Mapping Algorithms for Virtual Network Functions
Authors: Bouali Lyes , Khebbache Selma , Bouzefrane Samia , Daoui Mehammed
Published: June 2019

Background:

Network Functions Virtualization (NFV) is a paradigm shift in the way network operators deploy and manage their services. The basic idea behind this new technology is the separation of network functions from the traditional dedicated hardware by implementing them as a software that is able to run on top of general-purpose hardware. Thus, the resulting pieces of software are called Virtual Network Functions (VNFs). NFV is expected, on one hand, to lead to increased deployment flexibility and agility of network services and, on the other hand, to reduce operating and capital expenditures. One of the major challenges in NFV adoption is the NFV Infrastructure's Resource Allocation (NFVI-RA) for the requested VNF-Forwarding Graph (VNF-FG). This problem is named VNF-forwarding graph mapping problem and is known to be an NP-hard problem.

Objective:

To address the VNF-FG mapping problem, the objective is to design a solution that uses a meta-heuristic method to minimize the mapping cost.

Methods:

To cope with this NP-Hard problem, this paper proposes an algorithm based on Greedy Randomized Adaptive Search Procedure (GRASP), a cost-efficient meta-heuristic algorithm, in which the main objective is to minimize the mapping cost. Another method named MARA (Most Available Resource Algorithm) was devised with the objective of reducing the Substrate Network’s resources use at the bottleneck clusters.

Results:

The Performance evaluation is conducted using real and random network topologies to confront the proposed version of GRASP with another heuristic, existing in the literature, based on the Viterbi algorithm. The results of these evaluations reveal the efficiency of the proposed GRASP ‘s version in terms of reducing the cost mapping and performs consistently well across all the evaluations and metrics.

Conclusion:

The problem of VNF-FG mapping is formalized, and a solution based on GRASP meta- heuristic is proposed. Performance analysis based on simulations are given to show the behavior and efficiency of this solution.
Picrorhiza kurrooa Royle ex Benth., an Endangered Himalayan Elixir- Medicinal Importance and Exploration of Biotechnological Approaches in Picroside Production
Authors: Barsain Bharati Lalhal , Yadav Sudesh Kumar
Published: June 2019

Although the history of P. kurrooa Royle ex Benth., popularly known as “Kutki
or Kadu” dates back to the Vedic era, it has only been about 69 years since research has focussed
on exploring its pharmacological properties. It is a small perennial medicinal herb
that belongs to the Scrophulariaceae family. Found primarily in the north-western alpine
Himalayan region at the altitudes of 3000-4300 meters (amsl), the plant has immense
therapeutic and medicinal properties. Uniquely gifted, the plant holds its reputation in the
modern system of medicine in the treatment of liver disorders. The species has earned an
endangered status lately due to various issues like unawareness on its conservation,
harvesting methods, and cultivation besides others. Therefore, various new scientific
methods are being developed for its propagation and conservation. This article provides an
overview of the therapeutic properties, various mode of propagation as well as the molecular
aspects of P. kurrooa. Also, the metabolic engineering strategies to modulate its secondary
metabolite picrosides are also discussed.
ОСОБЛИВОСТІ ТОЛЕРАНТНОСТІ ДО ФІЗИЧНИХ НАВАНТАЖЕНЬ В ПОСТІНФАРКТНОМУ ПЕРІОДІ В ЗАЛЕЖНОСТІ ВІД НАЯВНОСТІ ДЕКОМПЕНСАЦІЇ ХРОНІЧНОЇ СЕРЦЕВОЇ НЕДОСТАТНОСТІ
Authors: Вакалюк І. П. , Левандовська Х. В.
Published: June 2019

Резюме. Ціль. Оцінити фізичну активність та доцільність використання тесту шестихвилинної ходьби у хворих з декомпенсованою СН у ранньому та пізньому постінфарктному періоді на фоні показників натрійуретичного пропептиду типу В.

Матеріали і методи дослідження. Було обстежено 160 пацієнтів з перенесеним інфарктом міокарда. Хворих було рандомізовано в 2 групи, залежно від наявності ознак декомпенсованої хронічної СН. Досліджені групи були однорідними за віком, статтю, важкістю перебігу захворювання, тривалістю постінфарктного періоду, наявністю клінічних проявів декомпенсації.

Результати дослідження та їх обговорення. Впродовж вивчення клінічних та електрокардіологічних ознак виконання фізичних навантажень, таких як депресія сегменту ST, стенокардія, задишка, симптоми з боку центральної нервової системи, було виявлено значне погіршення стану пацієнтів з діагнозом Q-QS та не-Q ІМ, ускладненим декомпенсованою СН. У результаті аналізу ТШХ було з’ясовано, що наявність декомпенсованої СН значно погіршує показники цієї навантажувальної проби. В осіб з ознаками декомпенсованої СН мали місце вірогідно вищі рівні NT–proBNP у сироватці крові і склали (850,54±20,51)пг/мл (p≤0,05) в порівнянні з першою групою (428,5±6,81) пг/мл (p≤0,05).

Висновки. У ході роботи встановлено, що неадекватна відповідь на дозовані фізичні навантаження, високий рівень NT–proBNP можуть бути корисними не тільки для ранньої діагностики та прогнозування виникнення декомпенсованої СН в ранньому та пізньому постінфарктному періоді, але і для прийняття рішення про оптимальне подальше диспансерне лікування такого контингенту хворих та рішення про виписку після госпіталізації.
НАБРЯК ГОЛОВНОГО МОЗКУ ТА РЕАКТИВНИЙ ПСИХОЗ ПІСЛЯ ПРОВЕДЕННЯ КОРОНАРНОЇ АНГІОГРАФІЇ І СТЕНТУВАННЯ
Authors: Уляновська М. І.
Published: June 2019

За даними літератури, неврологічним ускладненням після проведення процедури коронарної ангіографії і стентування приділяється недостатньо уваги, оскільки вони є нечастими. У статті представлено клінічний випадок хворого 45р., який поступив у кардіологічне відділення із симптомами стенокардії, що виникла вперше, для проведення планової коронарографії. В результаті обстеження виявлено критичний стеноз лівої коронарної артерії і проведено стентування ураженого сегмента. Після процедури у хворого прогресувала неврологічна симптоматика: загальмованість, згодом – різке психомоторне збудження, порушення мови, орієнтації в просторі і часі, с-м Бабінського з обох сторін. Під час комп’ютерної томографії виявлено набряк головного мозку, арахноїдальну кісту правої лобної частки конвекситально. Через погіршення загального стану хворого переведено до реанімаційного відділення, де на фоні проведеної терапії неврологічна симптоматика регресувала, виписаний у задовільному стані. У даного хворого виникло доволі унікальне ускладнення, причиною чого міг стати токсичний вплив ангіоконтрасту через скомпрометований неврологічний анамнез.
Cinema, migrações e diversidade cultural: nota introdutória
Authors: Cabecinhas Rosa , Macedo Isabel , França Renné
Published: June 2019

A intensificação dos fluxos migratórios e a crescente interconectividade “global” têm tornado evidente que um maior nível de contacto entre pessoas de diferentes culturas não se traduz automaticamente num maior interconhecimento e diálogo intercultural...
PILOT STUDIES OF PROCESS OF VIBROACOUSTIC DYNAMICS AT LOCAL HARDENING OF DETAILS A SHARIKO-ROD UPROCHNITEL
Authors: Morozov S. A. , Chukarin A. N.
Published: June 2019

Objectives The most important problem of modern mechanical engineering is increase in durability of products, their efficiency and competitiveness in the world market. The equipment for machining creates the increased noise levels in a working zone of operators. Now regularities of formation of acoustic characteristics are studied generally for metal-cutting and woodworking machines of various types. Formation of the sound field at shariko-rod hardening is studied insufficiently. The purpose of researches which results are given in this article consisted in studying of regularities of spectral structure of noise and vibrations when processing ShSU of details with various ways of fixing. Method. In the course of pilot studies the known methods of measurement and processing of experimental data in relation to acoustic and vibration characteristics were used. Results. It is established that noise ranges at ShSU of details with various ways of fixing have identical regularities of a shumoobrazovaniye and are characterized by pronounced high-frequency character. It is proved that the dominating sources yaa-lyatsya the strengthened detail and an uprochnitel. Conclusion. Sizes of excesses of levels of sound pressure systems "up-rochnitel-detal2 in a high-frequency part of a range 500-8000gts are installed. The established regularities of formation of spectral structure are a basis for the choice of means of decrease in noise levels. Work is performed within initiative research work.
El voto electrónico en la construcción de un modelo de democracia electrónica
Authors: Hernández Trejo Ninfa Elizabeth
Published: June 2019

El objetivo de este trabajo es presentar una propuesta de modelo de democracia electrónica a partir del uso político de la tecnología, particularmente del voto electrónico. Para ello, se analiza el empleo del voto electrónico en mecanismos de participación ciudadana, con lo cual es posible contribuir a la democracia electrónica, pues a diferencia de cuando se utiliza en procesos electorales, en éstos el votante se involucra en decisiones más elaboradas, como el destino del gasto público o el proceso legislativo; y lo puede lograr apoyándose de la tecnología para
generar canales de información, deliberación y toma de decisión
Research of freezing kinetics of water drop on superhydrophobic coating surfaces
Authors: Loganina About the author: Valentina I.
Published: June 2019

Introduction. Anti-icing coatings are used to prevent icing of the building roofs and power transmission line poles. One of the characteristics of anti-icing properties of superhydrophobic surfaces is the delay in the crystallization of drops on such surfaces. A significant delay in the crystallization of water drops on superhydrophobic substrates is noted in the scientific and technical literature. However, it is recorded in a number of papers that the delay time of crystallization on hydrophilic substrates is longer than the corresponding values on superhydrophobic surfaces. In connection with the foregoing, the study of the freezing kinetics of a water drop on a superhydrophobic surface in order to assess its efficiency is a relevant scientific and technical problem. Materials and methods. To evaluate the kinetics of freezing a of water drop on a superhydrophobic surface, the following experiment is conducted. A drop of water is placed on the superhydrophobic surface of the mortar substrate, which is placed in a freezer at a temperature of –18 °C. Studies of the drop freezing dynamics on the surface are performed using a Testo 875-1 thermal imager. To create a superhydrophobic surface, an aerosil R 972 with density ρ = 2360 kg/m3, particle size of 16 nm and specific surface area Ssp = 12 000 m2/kg is used as a filler. A silicone resin SILRES® MSE 100 of 10 % concentration is used as a binder. The obtained solutions are deposited on the mortar substrates. The degree of hydrophobicity is assessed by the magnitude of the wetting angle (θ°). Results. Results of the studies of temperature distribution on the water drop surface indicate that the distribution is uneven. The process of drop freezing is multistage. In the initial period, there is a transfer of heat from the surface into the water drop. This stage is followed by the process of drop freezing which is manifested in the upward movement of the freezing front from the substrate. Conclusions. It is revealed that the temperature distribution on the surface of a water drop is uneven. When freezing, a water drop has a pointed top.
Research of the toolkit features for the evaluation and development of project-oriented management in a full cycle engineering company
Authors: Kudrevatykh Vladimir V.
Published: June 2019

Introduction. Analysis of existing foreign and Russian project management maturity models revealed the absence of tools for assessing the maturity of project management, which would take into account the specifics of the functioning of engineering companies and the implementation of engineering projects. The uniformity of such models limits the list of evaluated aspects of project management, which does not allow to fully cover the project management processes operating in engineering companies. Such processes should include engineering, management of intangible assets, control and acceptance of the results of engineering works, management of construction and installation works, and so on. To solve the problem, it is necessary to develop special tools for the assessment and development of project management, which will take into account engineering-specific processes. The toolkit will allow to quantify the degree of implementation of the project approach to the activities of an engineering company and to plan the continuous improvement of the processes and tools of project management in it. The subject of the research is the development of tools for assessing and developing project-oriented management in a full-cycle engineering company.

Materials and methods. Applied the method of comparative analysis, survey method and method of semi-structured interviews.

Results. The article formulates the features of project management in engineering companies. The main types of maturity models of project management are considered, their distinctive features are revealed. Tools for the evaluation and development of project management for the Russian engineering company full cycle are formulated. The assessment of the levels of formalization of project management processes was carried out, their current and target states were determined. Set of measures for the development of processes and tools of project management is planned.

Conclusions. The toolkit for project management evaluation and development proposed in the article allows to carry out structural analysis of project management processes and the level of their formalization, to implement improvements based on the results of evaluation not only in the engineering company under consideration, but also in project-oriented organizations implementing similar projects.
المدخل الاتصالي في تعليم اللغة العربية
Authors: Asy’ari Hasyim
Published: June 2019

Humans need language in order to interact with society. They express their thoughts and intentions with language. Language is a communication tool in society.  And learning a foreign language not only learns grammar, but the ability to communicate with other communities. The approach that fits this purpose is the communicative approach. Communicative is the process of conveying thoughts and perceived by speech methods that include meaningful writing and a clear subject of thought. This approach aims to develop language competence in general by directing learners to language functions. Communicative ability is one's ability to grammatical adjustment and its use for certain communicative functions with cra corresponding to a particular place.
Culicoides (Diptera: Ceratopogonidae) from Ceará State, northeastern Brazil: Diversity, new records and bionomic approaches.
Authors: Felippe-Bauer Maria Luiza , Gonzaga Gilmara Pereira , Cavalcante Robson , Gomes Ricristhi , Silva Rafaella
Published: June 2019

Introduction: little is known about the biodiversity of the genus Culicoides and the possible presence of vector species in Ceará State, Brazil. Objective: to improve the knowledge about the biodiversity and possible vectors presence in northeastern Brazil. Methods: with CDC light traps we surveyed Culicoides species in 18 municipalities from six mesoregions of Ceará State. Results: we collected 1 453 specimens (12 species). Culicoides guyanensis was the most abundant species, with 75,84% of the collected specimens. Culicoides venezuelensis is well distributed and is found in five Mesoregions. We recorded five species for the first time from Ceará State and seven from the surveyed municipalities; the presence of species with sanitary importance is discussed. Conclusion: with the addition of new species records, there are now 12 species known from Ceará State. The presence of species with medical and/or veterinary importance in the studied Mesoregions is indicative of the need of epidemiological surveillance in this state.
Salute to Cleveland
Authors: Dykema Peter W.
Published: June 2019

THIS is a significant occasion for the 8,000 members of the Music Educators National Conference. We are now enjoying the generous hospitality of Cleveland. We are participating in the 150th anniversary of a prosperous, high-minded city; in the 100th birthday of organized teaching of music in the public schools of Cleveland; and, in our own fourth visit during the thirty-nine years of our organization, we are here to examine and applaud the outstanding efforts of the musicians of the local schools and those in the rest of the state. We were here first in 1908, just after we were organized, and have come three times since, because our present capable host, Russell V. Morgan, made us want to come again. One of the reasons for meeting here in 1923, 1932, and 1946 was to enjoy the benefits of the remarkable effects of the Cleveland Orchestra on the music education of the community. The founding of this fine orchestra in 1918 resulted from the engagement by The Musical Arts Association of Nikolai Sokoloff to come to Cleveland and make a survey of instrumental music teaching in the schools. For five years, The Musical Arts Association financed the salaries paid to the orchestra and made possible Saturday morning instrumental classes in the schools. It promises well for the music in our country that thirty-eight members of the Cleveland Orchestra had their early instrumental education in the public schools of their own city. Cleveland's program of audience education for children, young people, and adults is a joint enterprise of the Board of Education, the Public library, and the Cleveland Orchestra. Our Conference has gained much from your leaders, including Mrs. Adella Prentiss Hughes, Miss Lillian L. Baldwin and the great conductors and educators associated with this enterprise. It is a source of inspiration to know that the annual attendance of children at your orchestral concerts is 50,000 and that these concerts are but a portion of your well-organized and well-attended yearly musical events. Cleveland has demonstrated that the health and strength of a city flow from a wise combination of industry and art. The Music Educators National Conference salutes you! At the biennial convention in Cleveland, members of the MENC were guests of the Cleveland Orchestra on the occasion of the weekly broadcast concert at Severance Hall, March 30, 1946. During the concert, Peter W. Dykema was introduced and spoke to the assembled audience and the radio listeners. Because of the significance of his remarks, the full text of the script is reproduced here.
Sağlık İşletmelerinde Performans Değerlendirme ve Ölçme Yöntemleri Hakkında Bir Derleme Çalışması
Authors: KARAMAN Mesut , KUŞCU KARATEPE Hilal , KUŞCU Fatma Nuray
Published: June 2019

Sağlık
hizmetine olan talep her geçen gün artış gösterdiği gibi sağlık hizmeti veren
kuruluşların sayısı da bu doğrultuda artmaktadır. Yeni kurulan veya daha da
büyümeyi hedefleyen bir sağlık kurumu istenilen seviyeye gelebilmesi için etkin
bir performans yönetimini sağlaması gerekmektedir. Sağlık kurumlarında
belirlenen amaçlar ve hedefler doğrultusunda gerçekleştirilen faaliyetlerin
sonuçlarının tanımlanabilmesi, ölçülmesi, yapılan planlarla karşılaştırılması,
sonuçların değerlendirilmesi, geleceğe yönelik karar alma yönüyle birer kaynak
olması sebebiyle performans değerlendirmesi büyük önem taşımaktadır. Performans
yönetiminin kurumda etkin bir biçimde uygulanabilmesi için çalışanların
algılayabileceği düzeyde olmalı ve herkesin katılımı sağlanmalıdır. Sağlık kuruluşlarında
hizmet türünden dolayı standart bir performans değerlendirme sistemi ve yöntemi
yoktur. Sağlık kurumunun sunduğu hizmetin niteliğine göre performans
değerlendirme yöntemini seçmesi gerekmektedir. Bu çalışmada performans
değerlendirme yöntemlerinin literatürdeki çalışmalarla birlikte bir özeti
sunulmaktadır.
Analisis Kemampuan Komunikasi Matematis Ditinjau dari Tipe Kepribadian Guardian dan Idealist
Authors: Melya Lekok , Supriadi Nanang
Published: June 2019

The purpose of this study is to describe the mathematical communication skills of high school students in terms of guardian and idealist personality types. Subjects in this study were taken using a purposive random sampling technique of two students from class X senior high school in Bandar Lampung with different personality types, that is one student with guardian personality type and one student with a idealist personality type based on David Keirsey's personality dimensions, with personality type initial guardian (NAP) and initial idealist personality type (DBD). Mathematical communication skills are analyzed based on the following criteria : (1) the ability to write down what is known and asked about the questions; (2) the ability to write answers according to the purpose of the questions; (3) the ability to write down reasons for answering questions; (4) the ability to make mathematical terms and symbols; (5) the ability to make images that are relevant to the questions; (6) the ability to make conclusions in their own language. The results showed that subjects with guardian personality type were only able to master the five criteria of mathematical communication ability. The subject was unable to conclude with his own language. The results showed that subjects with idealist personality type were only able to master the five criteria of mathematical communication ability but the subject does not master the third criterian, the subject is unable to write down the reasons for answering the question.
Penerapan Taksonomi Bloom Revisi untuk Meningkatkan Kemampuan Pemahaman Konsep Matematis
Authors: Netriwati Netriwati
Published: June 2019

The ability to understand students' concepts is important. But the ability to understand the concept of students does not grow without just passing on an action from a serious educator in dealing with this problem. Developing learning objectives in general is one of the right steps taken by educators in learning. Bloom Revision Taxonomy that researchers will use in developing learning objectives in this study. so this study aims to describe students' abilities in understanding concepts through Bloom Revision's taxonomy. This type of research uses a qualitative descriptive method to see students' understanding of concepts in the implementation of microteaching in accordance with taxonomic steps of the revised bloom on the Education of Mathematics students at UIN Raden Intan in the sixth semester. Data collection techniques are tests on the implementation of microteaching and interviews. Based on the results of the assessment seen in the results of the observation sheet on the implementation of the learning that the steps of Bloom's Taxonomy can be applied in accordance with the selected indicators and in general students have been able to understand mathematical concepts well. So it can be concluded that the application of Bloom Revised Taxonomy in learning can improve students' ability to understand concepts
Analisis Kemampuan Pemecahan Masalah Matematis : Dampak Metode Drill ditinjau dari Gaya Belajar
Authors: Fransiska Cici , Masykur Ruhban , Putra Fredi Ganda
Published: June 2019

This study aims to determine the differences in the Drill method of mathematical problem solving abilities of participants, differences in students with visual, auditory or kinesthetic learning styles on problem solving abilities and interactions between learning methods and learners' learning styles on mathematical problem solving abilities. The method used is the Quasy Experiment method, this study uses analysis of variance (ANAVA) two ways with unequal cells. Data collection techniques are carried out by observation, interviews, documentation and questionnaire methods. The results showed that there were differences in the Drill Method towards students 'mathematical problem solving abilities, there was no difference in visual, auditory and kinesthetic learning styles towards mathematical problem solving abilities and there was no interaction between learning methods and learners' learning styles towards mathematical problem solving abilities, p. this is because learning methods (Drill methods and direct learning) and learning styles of students have the same effect on mathematical problem solving abilities.
Diseño e implementación de un sistema de visión artificial para análisis de datos NDVI en imágenes espectrales de cultivos de brócoli obtenidos mediante una aeronave pilotada remotamente
Authors: Bautista Rodrigo , Constante Patricia , Gordon Andrés , Mendoza Dario
Published: June 2019

El Índice de Vegetación de Diferencia Normalizada NDVI, se viene utilizando en el campo de la agricultura como indicador de la salud de las plantas, permitiendo diferenciar las zonas vegetadas de otras coberturas; y diferenciar la vegetación sana de aquella senescente o que se encuentra bajo algún tipo de estrés (ej. plagas, cambio de uso de suelo, etc.). Se presenta una técnica de visión artificial aplicada a la detección de características en el desarrollo de cultivos de brócoli, mediante la aplicación de un sistema de visión por computador, basado en imágenes espectrales adquiridas por medio de una cámara Survey 2 NDVI Red + NIR, adaptada a una plataforma aérea (drone) y procesadas en el lenguaje de programación Matlab para posteriormente a ello tener como resultado el NDVI de mencionados cultivos.
Post-Soviet Russia: Characteristics and Social and Political Contradictions
Authors:   Voronezh State Medical University, Ruzhentsev Sergey Evgenievich , Smirnov Aleksey Valentinovich ,   Voronezh State Medical University
Published: June 2019

The paper deals with the establishment of the social and political system of the post-Soviet Russia as an ambiguous process with many divergent develop-ment trends. At the same time, the authors assume that the post-Soviet Russia has developed in the context of the contradictory and dynamic interaction of the various social and political forces pursuing their interests and fulfilling their goals and ideas. The logic of the country’s evolution becomes clear to some extent in a historical retrospective. The main purpose of the study is to understand this logic as a certain sequence and interdependence of events and facts, political processes and trends, as a common development line of the post-Soviet Russian society. An attempt is made to iden-tify and explain the trends in the country’s evo-lution in the critical period of liberal market reforms. Using political science and philosophical tools, the authors analyze the direction and nature of changes in Russian social and political institutions and rela-tions in the 1990s, consider the opportunities and conditions of further country’s development scenar-ios in the post-Soviet period, and learn the les-sons from fundamental social transfor-mations. In their opinion, moderate authoritari-anism with the elements of illiberal democracy on the social and economic basis of state capitalism is the possible development scenario for Russia in the near future.
Reform of the UN Human Settlements Programme
Authors:   St. Petersburg State University, Simakov Mikhail Dmitrievich
Published: June 2019

The study focuses on the implementation of the United Nations Human Settlements Programme (UN-Habitat), the leading sustainable development pro-gramme, that is in crisis. In the author’s opinion, it has limitations in terms of credibility, efficiency, transparency, and accountability. It is obvious that UN-Habitat and the overall urban issues have low significance to the UN system. However, the importance of urbanization issues is extremely high in the context of sustainable development. This was acknowledged in the report of the High-level Independent Panel to Assess and Enhance the Effectiveness of UN-Habitat submitted to the UN General Assembly in 2017. The report stated the urgent measures should be taken to reform UN-Habitat’s governance structure and enhance its normative mandate. The transformation process was launched by the new executive director of the programme in 2018. The study proposes possible solutions to the above-mentioned problems and presents the first-year reform results. The author concludes that it is necessary to enhance the nor-mative mandate of UN-Habitat and establish the credibility of the programme’s assessment to im-prove the situation in settlements around the world and provide their sustainable development.
Prenylated Flavonols from the Leaves of Macaranga gigantea (Rchb.f. & Zoll.)
Authors: Mohd Johari Muhammad Sulaiman , Ahmat Norizan , Kamarozaman Aisyah Salihah , Mohd Isa Mohamad Hamizan
Published: June 2019

The genus Macaranga comes from the family of Euphorbiaceae and it is the only genus in the subtribe Macaranginae that have a large genus with 300 species of which 27 species were found in Peninsular Malaysia. This plant grows as shrubs or trees that can grow up to 15 m tall and known for their mutual associations with ants. Fresh or dried leaves of some Macaranga species were used by traditional healers to treat swellings, cuts, sores, boils, and bruises. The isolation of chemical constituent from this genus has been shown to produce numerous results of phenolic compounds, such as flavonoids and stilbenoids. In this paper, we report the isolation of a prenylated flavonol, glyasperin A (1), together with a simple flavone apigenin (2) from the methanolic extract of the leaves of Macaranga gigantea. The structure of both compounds has been elucidated based on its spectroscopic data, including mass spectroscopy (MS), infrared (IR), ultraviolet-visible (UV-Vis), 1D and 2D nuclear magnetic resonance (NMR) spectra and comparison with the previous literature.
PERILAKU KOMUNIKASI PENGGUNA AKTIF INSTAGRAM
Authors: Nugraha Bayu , Akbar M. Fakhrudi
Published: June 2019

Tujuan penelitian ini adalah untuk mengetahui faktor-faktor yang melatarbelakangi terjadinya perilaku komunikasi  pengguna aktif Instagram dan mengetahui perilaku komunikasi antar sesama pengguna aktif Instagram. Penelitian ini menggunakan metode kualitatif studi kasus. Teknik pengumpulan data menggunakan wawancara berulang kepada delapan orang informan, observasi, studi pustaka serta analisis dokumen yang berkaitan dengan penelitian ini.  Hasil dari penelitian ini mengungkapkan bawah faktor-faktor yang melatarbelakangi terjadinya perilaku komunikasi pengguna aktif instagram adalah fasilitas pendukung, keinginan untuk menghasilkan karya yang lebih baik, frekuensi mengakses yang tinggi serta dorongan kerabat. Perilaku komunikasi antar sesama pengguna aktif instagram yaitu mengunggah foto, melakukan following dan unfollow, memberikan like dan komentar, membubuhi informasi pada foto yang diunggah serta menghadiri kegiatan gathering dan photowalk.
Selebriti dalam Digital Activism Tentang KekerasanTerhadap Perempuan di YouTube
Authors: Maryani Eni , Astari Sarah
Published: June 2019

Penelitian ini membahas keterlibatan para selebriti dalam film ’16 days of Activism’ terkait isu kekerasan terhadap perempuan yang diunggah dalam you tube. Isu kekerasan terhadap perempuan masih perlu disebarluaskan ke masyarakat akan tetapi kuatnya nilai-nilai patriarki menjadikan isu ini cenderung terpinggirkan. Merujuk pada fenomena tersebut maka penggunaan beragam media dan aktor menjadikan sangat penting bagi proses advokasi untuk melawan tindak kekerasan terhadap perempuan. Metode yang digunakan studi kasus dengan pengumpulan data melalui wawancara mendalam, observasi dan studi dokumentasi. Penelitian mengungkapkan bahwa sinergi sebagai survivor, selebriti dan juga aktivis menjadi kekuatan bagi Hannah Ar Rashid untuk mengangkat wacana tentang kekerasan terhadap perempuan dan melibatkan selebriti lain dalam produksi filmnya untuk advokasi, You tube adalah salah satu media digital yang mampu mempermudah advokasi melalui film. Film ‘16 Days of Activism’ di you tube merupakan salah satu bentuk digital activism yang dilakukan para selebriti. Film advokasi yang melibatkan para selebriti mampu menjadi daya tarik bagi khalayak untuk menerima dan memahami isu kekerasan terhadap perempuan
PERSPEKTIF PEREMPUAN (BARAT) TENTANG PERKAWINAN CAMPURAN, POLIGAMI, DAN ISLAM, DALAM NOVEL DEUXIÈME FEMME KARYA CAROLINE POCHON
Authors: Intan Tania
Published: June 2019

The purpose of this study is to examine the perspective of the narrator, French female character, about the phenomenon of mixed marriage, polygamy, and Islam, which is contained in the Deuxième Femme novel 'Second Woman' by Caroline Pochon. To examine these matters, this study uses descriptive analysis methods with criticisms of feminist literature and theories of narratology, cross-culture, and identity. A structural approach is used to analyze the narrative structure that builds the narrator's frame of mind. The results of the study show that as a narrator who truly lives a mixed marriage, experiences polygamy, and has embraced Islam, Caroline Pochon realizes that mixed marriages are not easy to live by because she must try to maintain her identity as a French woman. He also found that polygamy was a cultural practice that had long existed in Senegal so that it was difficult to change, especially because local women themselves did not intend to fight it and men practiced it as a form of obedience to religion (Islam
Renewal Paradigm of the Ldii Community in Kediri
Authors: Muhammadiyah Hilmi
Published: June 2019

This article attempts to explore the dynamics of the Lembaga Dakwah Islam Indonesia (LDII) or Indonesian Islamic Da'wah Institution community in Kediri of East Java, Indonesia in maintaining its existence, transforming and seeing the processes, patterns, and strategies that developed by the LDII. The article elaborates how social actors of the LDII carry out social practices continuously so that LDII can continue to survive, develop, and reform the doctrine and religious identity paradigm and its organizational identity thus being accepted by people in the region. The role of the actors as the agent in changing the character of the movement is discussed in this work. They have made strategies including building closeness to the authorities, building attitudes of openness, changing the image of the organization, strengthening identity, establishing dialogue and public cooperation with the Indonesian Ulema Council (MUI – Majelis Ulama Indonesia) that positioning LDII as a heretical and splinter organization, and establishing cooperation with Religious Community Organizations (Ormas) that are considered mainstream, such as NU (Nahdatul Ulama) and Muhammadiyah. This work attempts to provide materials and considerations in dealing with the issue of raising between the flow of splinters and established groups.
Being Minority in Papua: Religious and Political Identity Struggle of the Dani Muslims
Authors: Yamin Ade , Abdullah Irwan , Nurmandi Achmad , Jubba Hasse , Qodir Zuli
Published: June 2019

The issue of religious and political identity of the Dani Muslims in Papua has been associated to social construction of the ethnic and religious aspects as the basis of political policies by the local government. The local government present in the form of Undang-Undang Otonomi Khusus Papua (UU OTSUS Papua) or the Law Number 21 of 2001 concerning Special Autonomy for Papua has been understood to become one of the keys playing roles in constructing the identity of people in modern Papua. This work attempts to review the process of becoming minority of the Dani Muslims within the context of the Papua society. They live in the central mountains with limited infrastructure and access to modern life. The work suggests that the Dani Muslim has become minority in terms of political representation as well as religious identity due to three conditions. First, the practice and implementation of the Law Number 21 of 2001 concerning Special Autonomy for Papua has significantly influenced the live of the Dani Muslims with regards to their political representation as well as religious identity. Second, they embrace Islam as a way of life and have to deal with the cultural conditions of the Dani community in general that are very consistent in maintaining their local tradition. Third, the domination of religious symbols used in public spaces has been found to have much influence to the identity of minority groups. The Christian Papuans later made further claims of Papua as the Land of Christ has had a broad impact not only on the access to public services for the Dani Muslims but has also presented them with new pressure and marginalized in terms of political position and religious group existence.
Effect of a two-base insertion mutation of the TP53 gene on expression of p53 protein in canine histiocytic sarcoma cells
Authors: Asada Hajime , Tomiyasu Hirotaka , Goto-Koshino Yuko , Ohno Koichi , Tsujimoto Hajime
Published: June 2019

OBJECTIVE

To examine effects of a common mutation (2-base insertion in exon 5) of the TP53 gene on biological function of p53 protein in canine histiocytic sarcoma cells.

SAMPLE

Canine histiocytic tumor cell lines DH82 with deletion of TP53 and CHS-3 with the wild-type TP53 and canine wild-type and mutant TP53 fragments.

PROCEDURES

Wild-type or mutant TP53 with a polyprotein peptide tag at the N-terminus was transduced into DH82 and CHS-3 cells. Expression of p53 protein, changes in function as a transcription factor, and susceptibility to doxorubicin and nimustine were compared.

RESULTS

Transduced p53 protein was detected in wild-type TP53–transduced DH82 and CHS-3 cells, whereas expression was not detected in mutant TP53–transduced cells. There were significant increases in expression of target genes of p53 protein, including p21 and MDM2, in wild-type TP53–transduced cells, compared with results for native and mock-transfected cells, but not in mutant TP53–transduced cells. There was no significant difference in drug susceptibilities among native and derivative cells of CHS-3. However, cell viabilities of wild-type TP53–transduced DH82 cells incubated with doxorubicin were significantly lower than viabilities of native, mock-transfected, and AT insertion mutation–TP53–transduced DH82 cells; susceptibility to nimustine did not differ significantly among cells.

CONCLUSIONS AND CLINICAL RELEVANCE

Expression of p53 protein and its function as a transcription factor were lost after addition of a 2-base insertion in the TP53 gene in canine histiocytic tumor cells. Additional studies are needed to investigate the clinical relevance of this mutation in histiocytic sarcomas of dogs.
AKR1D1*36 C>T (rs1872930) allelic variant is associated with variability of the CYP2C9 genotype predicted pharmacokinetics of ibuprofen enantiomers – a pilot study in healthy volunteers
Authors: Kapedanovska Nestorovska Aleksandra , Jakjovski Krume , Naumovska Zorica , Sterjev Zoran , Geskovska Nadica Matevska , Mladenovska Kristina , Suturkova Ljubica , Dimovski Aleksandar
Published: June 2019

The relative contribution of CYP2C9 allelic variants to the pharmacokinetics (PK) of ibuprofen (IBP) enantiomers has been studied extensively, but the potential clinical benefit of pharmacogenetically guided IBP treatment is not evident yet. The role of AKR1D1*36C>T (rs 1872930) allelic variant in interindividual variability of CYP450 mediated drug metabolism was recently elucidated. A total of 27 healthy male subjects, volunteers in IBP single-dose two-way cross-over bioequivalence studies were genotyped for CYP2C9*2, CYP2C9*3 and AKR1D1*36 polymorphisms. The correlation between CYP2C9 and AKR1D1 genetic profile and the PK parameters for S-(+) and R-(−)-IBP was evaluated. Remarkable changes in the PK values pointing to reduced CYP2C9 enzyme activity were detected only in the CYP2C9*2 allelic variant carriers. Statistically significant association between the AKR1D1*36 allele and the increased IBP metabolism (low AUC
0-t and 0–∞, high Cl
tot and short t
max values for both enantiomers) was observed in subjects carrying the CYP2C9 *1/*3 or CYP2C9*1/*1 genotype. The clinical value of concomitant CYP2C9 and AKR1D1 genotyping has to be further verified.
Dual skew Heyting almost distributive lattices
Authors: Assaye Berhanu , Alamneh Mihret , Mishra Lakshmi Narayan , Mebrat Yeshiwas
Published: June 2019

In this paper, we introduce the concept of dual skew Heyting almost distributive lattices (dual skew HADLs) and characterise it in terms of dual HADL. We define an equivalence relation θ on a dual skew HADL L and prove that θ is a congruence relation on the equivalence class [x]θ so that each congruence class is a maximal rectangular subalgebra and the quotient [y]θ/θ is a maximal lattice image of [x]θ for any y ∈ [x]θ. Moreover, we show that if the set PI (L) of all the principal ideals of an ADL L with 0 is a dual skew Heyting algebra then L becomes a dual skew HADL. Further we present different conditions on which an ADL with 0 becomes a dual skew HADL.
Multiplicative topological descriptors of Silicon carbide
Authors: Virk Abaid ur Rehman , Abbas Tanveer , Khalid Wasim
Published: June 2019

Topological indices helps us to collect information about algebraic graphs and gives us mathematical approach to understand the properties of chemical structures. In this paper, we aim to compute multiplicative degree-based topological indices of Silicon-Carbon Si
2
C
3
−III[p,q] and SiC
3
−III[p,q] .
Finding Hidden Structures, Hierarchies, and Cores in Networks via Isospectral Reduction
Authors: Bunimovich Leonid , Smith Dallas , Webb Benjamin
Published: June 2019

The method of isospectral network reduction allows one the ability to reduce a network while preserving the network’s spectral structure. In this paper we describe a number of recent applications of the theory of isospectral reductions. This includes finding hidden structures, specifically latent symmetries, in networks, uncovering different network hierarchies, and simultaneously determining different network cores. We also specify how such reductions can be interpreted as dynamical systems and describe the type of dynamics such systems have. Additionally, we show how the recent theory of equitable decompositions can be paired with the method of isospectral reductions to decompose networks.
Steady flow of a power law fluid through a tapered non-symmetric stenotic tube
Authors: Ahmad Riaz , Farooqi Asma , Zhang Jiazhong , Ali Nasir
Published: June 2019

A steady flow of a power law fluid through an artery with a stenosis has been analyzed. The equation governing the flow is derived under the assumption of mild stenosis. An exact solution of the governing equation is obtained, which is then used to study the effects of various parameters of interest on axial velocity, resistance to flow and shear stress distribution. It is found that axial velocity increases while resistance to flow decreases when going from shear-thinning to shear-thickening fluid. Moreover, the magnitude of shear stress decreases by increasing the tapering parameter. This problem was already addressed by Nadeem et al. [14], but the results presented by them were erroneous due to a mistake in the derivation of the governing equation of the flow. This mistake is highlighted in the "Formulation of the Problem" section.
EU Project of Life Programme “Algae Service for Life” Creates Tools for Ecological Service to Mitigate Cyanobacteria and Macroalgae Blooms in Freshwater Ecosystems
Authors: Koreivienė Judita , Karosienė Jūratė , Kasperovičienė Jūratė , Paškauskas Ričardas , Messyasz Beata , Łęska Bogusława , Pankiewicz Radosław , Gulbinas Zenonas , Valskys Vaidotas , Walusiak Edward , Krzton Wojciech , Kustosz Dominika , Wilk-Woźniak Elźbieta
Published: June 2019

EU international project of LIFE programme “Algae Service for LIFE” seeks to promote best practices in ecological service and development of circular economy. The goal of the project is to demonstrate integrated efficient management of nutrients and nuisance algal blooms at the catchment scale by harvesting cyanobacteria scums and macroalgae mats in various types of water bodies (rivers, lakes and estuarine lagoon). Also, it seeks to raise awareness of the national and local authorities, business community and society on the environmental, water quality and health hazard issues. The paper provides the idea of applying ecological measures to control algal blooms. Thus, issues related to the causes and mechanisms of eutrophication in inland freshwaters as well as to consequences such as algal blooms are highlighted. The measures proposed in the project are briefly discussed in the light of European Union directives.
Hybrid Time-Base Device for Coherent Sampling Oscilloscope
Authors: Tankeliun Tomas , Zaytsev Oleg , Urbanavicius Vytautas
Published: June 2019

In this paper, a hybrid time-base (HTB) device for the coherent sampling oscilloscope is presented. The HTB device makes it possible to reduce the uncertainty of determining the time position of the sample in the horizontal channel of the sampling oscilloscope. For its functioning, the proposed HTB device requires that the system-under-test, in addition to the test signal, also has a synchronous reference clock – harmonic oscillation. It should be noted that both the test signal and the harmonic reference clock are sampled simultaneously. The harmonic reference clock is connected to one of the oscilloscope channels and a special algorithm processes the clock samples and adjusts the coherent sampling mode. Two techniques of determining the position of the sample on the time axis are combined in the HTB device – the “trigonometric”, when the position is calculated by the arccosine or arcsine formula of the reference clock sampling value, and the interpolation method, according to which the time position of the sample is found by averaging the positions of two adjacent samples, obtained using said “trigonometric” technique. Primary experimental studies have shown that using the HTB device can reduce jitter of the sampling oscilloscope by several times and the drift with constant time distortion components is practically absent in this device.
Media disruption and the public interest
Authors: Syvertsen Trine , Donders Karen , Enli Gunn , Raats Tim
Published: June 2019

Digitization, new entrants and the disruption of business models prompt concern about the media’s societal mission. The article investigates how media managers conceptualize societal responsibility in an era of turmoil. Based on 20 semi-structured interviews with executive managers of private media companies in Norway and Flanders, the study reveals important differences in the definition of the public interest. While Flemish media managers emphasize brand value, Norwegian managers emphasize societal values, such as educating the public. When comparing managers of traditional and newer companies, a third, more straightforward market logic is also elicited, illuminating the vulnerability of traditional values.
Disrupting video game distribution
Authors: Werning Stefan
Published: June 2019

This article analyses the disruptive potential of Valve’s game distribution platform, Steam, focusing specifically on how Steam has evolved into a de facto online social network and how Valve uses constant feature changes as part of its corporate rhetoric. Despite its profound influence on the video game industry, scholarly inquiry into Steam has focused on analyses of user or value creation. However, Steam arguably derives its long-term disruptive potential from combining the gamification of digital distribution with the formation of ephemeral public spheres around the games that it distributes, thereby becoming a de facto online social network. To investigate this strategy, the article employs a historically comparative affordance analysis, drawing on a small data set of Steam blog posts and tech blog coverage from 2007 to 2018 to map patterns of affordance change.