Assessment of the Nature of Dyslipoproteinemias and Correlations of Indicators of General Reactivity and Lipid Metabolism in Patients with Chronic Nonspecific Inflammation of the Reproductive System
Authors:   Zaporizhzhya State Medical University and Khorticky National Academy, Sokolovskaya Irina , Prybora Nataliia ,   National Pedagogical Dragomanov University, Nechyporenko Valentyna ,   Municipal Institution of Higher Education «Khortytsia National Educational and Rehabilitational Academy» of Zaporizhzhia Regional Council, Zaporizhzhia, Ukraine, Pozdniakova Olena ,   Municipal Institution of Higher Education «Khortytsia National Educational and Rehabilitational Academy» of Zaporizhzhia Regional Council, Zaporizhzhia, Ukraine, Hordiienko Nataliia ,   Municipal Institution of Higher Education «Khortytsia National Educational and Rehabilitational Academy» of Zaporizhzhia Regional Council, Zaporizhzhia, Ukraine, Antonenko Iryna ,   Municipal Institution of Higher Education «Khortytsia National Educational and Rehabilitational Academy» of Zaporizhzhia Regional Council, Zaporizhzhia, Ukraine, Nechyporenko Kostiantyn ,   Municipal Institution of Higher Education «Khortytsia National Educational and Rehabilitational Academy» of Zaporizhzhia Regional Council, Zaporizhzhia, Ukraine, Serhata Nataliia ,   Municipal Institution of Higher Education «Khortytsia National Educational and Rehabilitational Academy» of Zaporizhzhia Regional Council, Zaporizhzhia, Ukraine, Siliavina Yuliia ,   Municipal Institution of Higher Education «Khortytsia National Educational and Rehabilitational Academy» of Zaporizhzhia Regional Council, Zaporizhzhia, Ukraine, Zarytska Valentyna ,   Classical private university, Bielan Olha ,   University of Economics Department «Economics and Organisation of Tourism», Pokropyvnyi Oleksandr ,   KL "Feofania" DUS, Yunger Vitaliy ,   KL "Feofania" DUS, Yanitka Lesya ,   Bogomolets National Medical University, Galtseva Tetyana ,   Oles Honchar Dnipro National University, Kryachok Iryna ,   National Cancer Institute, Tytorenko Iryna ,   National Cancer Institute, Varakuta Maryna ,   Dnipro Humanitarian University, Mavrin Vitalii ,   Municipal Institution of Higher Education «Khortytsia National Educational and Rehabilitational Academy» of Zaporizhzhia Regional Council, Zaporizhzhia, Ukraine, Kmetyuk Yaroslav ,   KL "Feofania" DUS
Published: January 2024

Metabolic disorders can occur at all levels of biological organization - from molecular and cellular to the level of the organism as a whole. These changes may result from disruptions in hormonal mechanisms, actions of pathogenic factors, or infections. Primary metabolic disorders are the basis of many diseases, such as diabetes, obesity, and atherosclerosis, while secondary disorders accompany most pathological processes. Disruption of lipid metabolism leads to changes in their functions and the development of pathological processes, such as dyslipoproteinemia, and also contributes to the development of atherosclerosis. Various intracellular infectious agents play a significant role in the development of dyslipoproteinemias and atherosclerosis, for example, chlamydia can alter the lipid metabolism in macrophages under the influence of low-density lipoproteins, leading to the formation of 'foam-like' cells. This, in turn, contributes to the development of atheromatous plaques-a favorable environment for chlamydia, where it can survive for an extended period and trigger immunopathological mechanisms.