bluuebunny/crossref_metadata_2025 huggingface dataset:
Multidimensional human wellbeing in periodic octopus closures
Authors: O'Neill Elizabeth Drury , Daw Tim M. , Lindkvist Emilie , MWAMBAO  , Martínez Jineth Berrío , Wamukota Andrew , Mwaipopo Rosemarie
Published: September 2023

This paper investigates multidimensional human wellbeing in periodic octopus closures, a common type of marine protected area (MPA) in the western Indian ocean. We trace the perceived flow of benefits, costs and trade-offs from closures at three sites in Zanzibar. We specifically explore how different types of fishers and traders perceive the impacts of closures on wellbeing from a personal, livelihood group and village or community level, as well as ecosystem effects. Our interpretive methods which prioritized participants' emic descriptions and understandings of closure impacts. We iteratively, qualitatively coded data using a three-dimensional (material, relational and subjective) social wellbeing approach. Despite different conditions and histories at the three sites, participants identified similar wellbeing attributes as affected by the closure. Themes included social conflict, non-compliance, income, education, food/nutrition, perceptions of inequity and communal benefits reflecting recent literature on MPAs and human wellbeing Gender was a strong dimension that emphasized procedural and distributional inequity between different types of livelihood groups e.g. small-scale traderwomen and male skindivers. Material wellbeing losses due to poor market environments highlighted how better alignment is needed between periodic closure activities and resulting trade and market dynamics. Opening events thoroughly impacted wellbeing across all dimensions, suggesting that these moments are critical for creating positive perceptions or losing support for closures.
Compliance, Complexity and Cephalopods- Disaggregated Responses to Participatory Marine Conservation & Management
Authors: O'Neill Elizabeth Drury , Daw Tim M. , Lindkvist Emilie , MWAMBAO  , Mwaipopo Rosemarie
Published: September 2023

Breaking of rules, whether formal regulations, or community agreed norms, remains one of the most widespread challenges to sustainable use of marine ecosystems. Non-compliance is especially difficult in small-scale fisheries as it can undermine the provision of nutrition and livelihoods to the many millions dependent worldwide. Although fishery compliance scholarship today is expanding beyond non-economic explanations of (non)-compliance behaviour, approaches and theory used fail to show the diversity of perceptions and dispositions that can underpin motivations. Thus a fuller understanding is lacking towards addressing the acute need for increased fisheries compliance. This paper takes a Zanzibari case of a rapidly spreading community-based intervention - periodic octopus closures - to explore compliance outcomes amongst a diverse range of participants. We take a qualitative approach aligning with an interpretive paradigm to carry out story circles, photo elicitation tasks and focus groups at three sites in 2019. Two sociological strands of theory were used to interpret how participants justify, are motivated by or dispositioned towards rules, rule-makers and rule-breakers. Generally the intervention was supported, signalling the potential for future compliance most commonly based on recognition of a degraded marine ecosystem in need of protection. However the diverse and dynamic responses by groups indicated on which basis and through which logics compliance behaviour was condoned or legitimated. This type of insight can aid managers gauge or anticipate the potential for non-compliance in participatory approaches that can impact the health of marine ecosystems.
Breaking the Code: An Investigation on The Vocal Registers of Malaysia’s National Songstress Puan Sri Saloma
Authors: Nur Fardilla Nadia Abu Bakar  , Mohd Fairuz Zamani
Published: September 2023

Investigations on vocal registers have been a great subject of debate. Early vocal pedagogues and scholars like Bacilly (1668–1690) and Behnke (1836–1892) paved the way for the modern-day investigation to take place through the categorisation of vocal registers across various music genres such as classical, jazz, and popular. However, an investigation on the vocal registers of Puan Sri Saloma (1935–1983) as a popular music icon of Malaysia has yet to be done. This paper intends to examine Saloma’s vocal registers through vocal analysis of five selected songs using case study as its research design. These songs are transcribed using music notation software (Sibelius) and analytical diagrams using similar software are produced to show the use of chest, middle, and head registers in each song. The finding shows the usage of the said registers and a diagram of Saloma’s vocal range is then produced, proving that Saloma was an alto. This study does not intend to limit Saloma’s vocal capability, but rather to celebrate her vocal prowess and encourage other scholars to conduct further investigations concerning Saloma as Malaysia’s national songstress.
Pera+Flora+Fauna: The Story of Indigenousness and the Ownership of History @ 59th Venice Biennale (23 April–27 November 2022)—An Exhibition Review
Authors: Nicole Chang Shu Fun
Published: September 2023

Commissioned by the People of Remarkable Talents (PORT), the Perak state’s creative and cultural agency, the exhibition, entitled Pera+Flora+Fauna: The Story of Indigenousness and the Ownership of History was curated as one of the official collateral events in the 59th International Art Exhibition of La Biennale di Venezia. It highlights the local inquiries and interpretations of indigenousness, ownership of history and nature through creative expressions of contemporary artists, towards further interrogating the inter-affecting relationships between inhabitants, culture, and nature in the context of Perak state (La Biennale di Venezia 2022; Nabila 2022; PORT 2022a). Through interviews with the stakeholders involved (i.e., organising and management team, curatorial team, and participating artists), this article reviews the curation, the exhibits, and the outreach of exhibition.
CAR T-клеточная терапия множественной миеломы по материалам конгрессов ASH-2021 и ASCO-2022
Authors: Семочкин Сергей Вячеславович
Published: September 2023

Current treatment of multiple myeloma (ММ) based on proteasome inhibitors, immunomodulating drugs, and monoclonal antibodies has, to a certain extent, reached the limit of its potential. Despite considerable clinical advance, ММ still remains a chronic incurable disease. Tumor-specific T-cell therapy with chimeric antigen receptor (CAR) is a new evolution step towards achieving MM cure. Today, B-cell maturation antigen (BCMA) is regarded as the primary target of CAR-T treatment of MM. This receptor is mainly expressed on the surface of tumor plasma cells in ММ as well as in B-cells of late differentiation stages and normal plasma cells. In 2021–2022, two CAR-T drugs, idecabtagene vicleucel (ide-cel) and ciltacabtagene autoleucel (cilta-cel), were approved for clinical use in the USA and the European Union for patients with relapsed/refractory MM. The studies of these drugs yielded encouraging clinical results. Other antigen (GPRC5D, SLAMF7) cell-based drugs are now in early stages of development. The present review is concerned with latest advances in CAR-T therapy for MM reported at the recent congresses ASH-2021 and ASCO-2022. The review comprehensively discusses the results of the KarMMa (ide-cel, stage II) and CARTITUDE-1 (cilta-cel, stage IB/II) studies. It also provides historical background of CAR-Т cell generation as well as preclinical and on-going clinical trial data on MM. It outlines potential failure causes and prospects of further improvement of the new technology.of its potential. Despite considerable clinical advance, ММstill remains a chronic incurable disease. Tumor-specific T-cell therapy with chimeric antigen receptor (CAR) isa new evolution step towards achieving MM cure. Today,B-cell maturation antigen (BCMA) is regarded as the primary target of CAR-T treatment of MM. This receptor is mainlyexpressed on the surface of tumor plasma cells in ММ aswell as in B-cells of late differentiation stages and normalplasma cells. In 2021–2022, two CAR-T drugs, idecabtagene vicleucel (ide-cel) and ciltacabtagene autoleucel(cilta-cel), were approved for clinical use in the USA andthe European Union for patients with relapsed/refractoryMM. The studies of these drugs yielded encouraging clinical results. Other antigen (GPRC5D, SLAMF7) cell-baseddrugs are now in early stages of development. The presentreview is concerned with latest advances in CAR-T therapyfor MM reported at the recent congresses ASH-2021 andASCO-2022. The review comprehensively discusses theresults of the KarMMa (ide-cel, stage II) and CARTITUDE-1(cilta-cel, stage IB/II) studies. It also provides historicalbackground of CAR-Т cell generation as well as preclinicaland on-going clinical trial data on MM. It outlines potentialfailure causes and prospects of further improvement of thenew technology.
Особенности течения новой коронавирусной инфекции COVID-19 у пациентов с онкогематологическими заболеваниями
Authors: Романенко Николай Александрович , Шилова Е. Р. , Стельмашенко Л. В. , Кайтанджан Е. И. , Кулешова А. В. , Стижак Н. П. , Чеботкевич В. Н. , Сидоркевич С. В. , Грицаев С. В. , Бессмельцев С. С.
Published: September 2023

Background. The novel coronavirus infection SARS-CoV-2 (COVID-19) is one of high-threat respiratory diseases, characterized by multiple organ disorders with primary respiratory failure and population mortality of 2–5 %. However, the mortality of oncohematological patients treated with chemotherapy is considerably higher.

Aim. To analyze the COVID-19 treatment outcomes in hematological malignancy patients who received drug chemotherapy.

Materials & Methods. The clinical course of COVID-19 was analyzed in 32 hematological malignancy patients aged 31–81 years (median 62 years). The disease onset was the date of the first positive COVID-19 PCR test. These patients were transferred to an infectious hospital specialized in the therapy of the novel coronavirus infection. Pneumonia was confirmed by standard radiography and CT. Blood oxygen saturation, body temperature, ECG, and respiratory rate were monitored. Moderate and severe COVID-19 was observed in 17 (53.1 %) of 32 patients. The condition of 15 (46.9 %) patients was described as good. For comparison, a control group was collected from 32- to 79-year-old (median 63 years) patients (n = 28) having hematological malignancies but no COVID-19.

Results. Nine (28.1 %) of 32 patients under analysis died upon increasing respiratory and multiple organ insufficiency on Day 3–17 (mean 8,6 ± 4,6 days) from the first positive COVID-19 PCR test. Death was predominantly reported in multiple myeloma patients (n = 5) as well as in a patient with Waldenstrom’s macroglobulinemia. In the control group (n = 28) with similar hematological tumors but without COVID-19, three (10.7 %) patients died throughout the 12-month follow-up period. The present paper contains a case report illustrating the clinical features of coronavirus infection in a patient with Waldenstrom’s macroglobulinemia, a monoclonal gammopathy with primary bone marrow lesions.

Conclusion. COVID-19 is a life-threatening viral disease with high mortality in patients with hematological malignancies, especially those with plasma cell dyscrasias.
Прогностические модели в медицине
Authors: Лучинин Александр Сергеевич
Published: September 2023

Medical prognostic (prediction) models (MPM) are essential in modern healthcare. They determine health and disease risks and are created to improve diagnosis and treatment outcomes. All MPMs fall into two categories. Diagnostic medical models (DMM) aim at assessing individual risk for a disease present, whereas predictive medical models (PMM) evaluate the risk for development of a disease and its complications in future. This review discusses DMM and PMM characteristics, conditions for their elaboration, criteria for medical application, also in hematology, as well as challenges of their creation and quality check.
Комбинация ибрутиниба и венетоклакса в терапии хронического лимфолейкоза: обзор последних данных клинических исследований
Authors: Петренко А. А. , Кислова Мария Игоревна , Дмитриева Е. А. , Никитин Е. А. , Птушкин В. В.
Published: September 2023

New Bruton’s tyrosine kinase (BTK) inhibitors caused drastic modifications in the therapy of chronic lymphocytic leukemia (CLL). Ibrutinib, the first in its class BTK inhibitor, showed high efficacy in many clinical studies. However, the treatment with BTK inhibitors as monotherapy must not be discontinued. Ibrutinib monotherapy inevitably leads to BTK inhibitor resistance and severe adverse events, which often results in treatment failure. Inhibitor BCL-2 venetoclax combined with BTK inhibitor can increase the therapy efficacy due to the synergetic effect of these agents on different CLL cell populations. Combined therapy potentially providing fixed-duration treatment can yield deeper responses. The present review focuses on ibrutinib and venetoclax combination, summarizes the latest data from clinical studies, and deals with feasibility of combined therapy in terms of its efficacy and safety profile.
Хронический гепатит С и онкогематологические заболевания
Authors: Антонова Тамара Васильевна , Ножкин М. С. , Лиознов Д. А.
Published: September 2023

This review focuses on HCV infection in oncohematological patients. High risk of hepatitis C virus (HCV) infection within this group of patients was proved by a significantly (2.0–2.5 times) higher HCV infection rate in non-Hodgkin’s lymphoma patients compared to population data. Besides, the review demonstrates the importance of HCV in the development and progression of B-cell non-Hodgkin’s lymphomas, which is confirmed by its tumorigenicity. The paper reviews the variant of seronegative (occult) hepatitis С, which is characterized by HCV RNA detected in liver tissue and peripheral blood mononuclear cells by highly sensitive reverse transcription PCR with the absence of serum HCV and HCV RNA antibodies. In this case, patients can present a source of infection. Seronegative hepatitis С is detected in donor blood in 2.2–3.4 % of cases. This infection variant is identified in 20–85 % of oncohematological patients, which needs to be further examined. Comorbid HCV infection is a potential prognostic factor in oncohematological diseases. Oncohematological patients with comorbid chronic hepatitis C (CHC) show considerably worse survival as compared with patients without it. HCV infection is associated with increased complication rates in both chemotherapy and hematopoietic stem cell transplantation (HSCT). Immunochemotherapy, on the other hand, affects CHC exacerbation and progression. High efficacy and good tolerability of direct-acting antiviral agents (DAA) in CHC therapy opened new prospects for their wide use in cases of comorbid diseases. HCV treatment in patients after HSCT still remains an issue. The guidelines for CHC treatment are predominantly formulated with a view to antiviral pre-HSCT therapy which is not always feasible in real-world clinical practice. The review contains examples of effective use of DAA drugs before or after HSCT and a case of antiviral treatment administered simultaneously with HSCT.
Определение соматических мутаций в гене EZH2 и оценка их прогностической значимости при фолликулярной лимфоме 1–3А цитологического типа
Authors: Нестерова Екатерина Сергеевна , Северина Н. А. , Бидерман Б. В. , Судариков А. Б. , Ковригина А. М. , Обухова Т. Н. , Мангасарова Я. К. , Куликов С. М. , Звонков E. E. , Паровичникова Е. Н. , Савченко В. Г.
Published: September 2023

Aim. To determine the incidence and prognostic value of mutations in exon 16 of EZH2 as well as those of polymorphism с.1582-21А>G (rs2072407) in EZH2 in patients with follicular lymphoma (FL) grades 1–3А in relation to morphologic and cytogenetic tumor characteristics.

Materials & Methods. The prospective cohort study conducted by the National Research Center for Hematology from January 2017 to April 2021 enrolled 80 patients with newly diagnosed FL grades 1/2 and 3А. The median follow-up was 53 months. Molecular and cytogenetic analyses were based on biopsy samples of lymph nodes obtained before chemotherapy. The mutation status of exon 16 in EZH2 and the presence of intronic polymorphism rs2072407 in EZH2 were examined by Sanger sequencing method. Translocation t(14;18)(q32;q21) was detected by karyotyping or FISH.

Results. Mutations in exon 16 of EZH2 (mutEZH2) were identified in 10/80 (13 %) patients. All patients showed missense mutation in codon 646 of EZH2. Translocation t(14;18) was detected in 45/80 (56 %) cases. Poor outcome in the cohort with no t(14;18) was observed 3 times more often than in the group of patients with t(14;18) (p = 0.0001). The presence of t(14;18) was associated with favorable prognosis irrespective of either the mutation status of exon 16 in EZH2 or the FL grade. The analysis of the polymorphism rs2072407 status yielded the following genotypes: AA in 24 % (n = 19), AG in 42 % (n = 34), and GG in 34 % (n = 27) of cases. The variants АА and AG were associated with higher risk of death (hazard ratio 2.9; 95% confidence interval 1.2–10.6; p = 0.01), whereas the genotype GG was associated with wtEZH2 (10 % vs. 37 %) and favorable prognosis (p = 0.065).

Conclusion. Significant biological markers for favorable prognosis in FL appeared to be the presence of t(14;18)(q32;q21) and GG genotype of polymorphism rs2072407 in EZH2. The previously identified prognostic factors (grade 3А, bulky tumor lesions > 6 cm, Ki-67 > 35 %, and a short interval between symptom onset and chemotherapy start) were incorporated into a new unified personalized predictive (index PPI) FL model by supplementing it with two additional biological markers: the presence of t(14;18)(q32;q21) and GG genotype of polymorphism rs2072407. This approach may increase the prognostic value of the new personalized design which will provide the basis for risk-adapted algorithms for FL treatment.
Субпопуляционный состав T-хелперов у больных острыми лейкозами после трансплантации аллогенных гемопоэтических стволовых клеток
Authors: Давыдова Юлия Олеговна , Капранов Н. М. , Никифорова К. А. , Караваева О. С. , Камельских Д. В. , Дроков М. Ю. , Кузьмина Л. А. , Гапонова Т. В. , Гальцева И. В. , Паровичникова Е. Н.
Published: September 2023

Aim. To identify the characteristics of T-helper subpopulations in healthy donors and to compare them with those reported in acute leukemia patients 6 months after allogeneic hematopoietic stem cell transplantation (allo-HSCT).

Materials & Methods. The study enrolled 41 blood donors and 49 patients after-HSCT. The median age of donors was 36 years (range 20–60 years), 29 of them were men and 12 were women. The median age of patients was 37 years (range 19–62 years), 18 of them were men and 31 were women. Acute myeloid leukemia was diagnosed in 27 (55 %) patients and acute lymphoblastic leukemia/lymphoma in 22 (45 %) patients. Myeloablative conditioning was administered to 4 (8 %) patients and reduced intensity conditioning to 45 (92 %) patients. T-helper subpopulations were studied in the blood of healthy donors vs. acute leukemia patients after allo-HSCT. The flow cytometry analysis was conducted to simultaneously assess the expression of markers CD3, CD4, CD8, CD25, CD45RA, CD197, CD28, CCR4, CCR6, CCR10, CXCR3, and CXCR5 in T-cells.

Results. The study demonstrated that the count of T-helpers at different stages of differentiation (regulatory, naive T-cells, memory cells, and effector cells) comprehensively distinguishes healthy donors from patients. Moreover, the functional structure of each of these populations differ in donors vs. patients even on Month +6 after allo-HSCT. Donors appeared to have more polarized cells among the central memory T-helpers. The proportion of T-helpers type 1 among the effector cells was higher is patients.

Conclusion. The results of the study indicate that the Т-cell parameter set can be analyzed to assess immunity and to describe its disorders in different pathologies or after drug chemotherapy.
The Impact of Creative Writing Activity on EFL Learners' Non-Core Vocabulary Acquisition
Authors: Jurado Antonio Moreno
Published: September 2023

In the context of ELT and EFL classrooms, creative writing has been underutilized in language learning and critical consciousness development (Stillar, 2013). This paper presents a quantitative approach that aims to explore the impact of a creative writing activity in terms of non-core vocabulary acquisition within B2-level EFL classrooms. By conveying a set of in-class and autonomous creative writing activities, the study deepens not only into vocabulary acquisition but also into second language acquisition (SLA) purposes. The investigation aims to discover the extent to which the instruction of creative writing activities fosters EFL learners’ acquisition of non-nuclear vocabulary. Following a quantitative methodology, a non-core vocabulary pre-test and post-test were administered to students. These tests included sections for analyzing students' knowledge of non-core vocabulary and the linguistic repertoire used in vignette descriptions (strip comics). Results from a paired samples t-test suggested that integrating creative writing activities in EFL environments not only enhanced lexical acquisition but also fostered detachment from cultural nuances and the influence of the students' mother tongue. All the scrutinized elements within the students’ linguistic repertoire were improved after the creative writing instruction. Within this analysis, the verbs and adjectives were the elements that were the most improved in terms of specificity and concreteness. Overall, the study sheds light on the potential benefits of integrating creative writing activities in EFL classrooms. The findings hold promising implications for EFL educators seeking innovative strategies to enhance language learning and intercultural competence.
Flood simulation using the hydrological model and the hydrological–hydrodynamic coupling model in a small watershed in semi-arid and sub-humid region, North China
Authors: Li Jianzhu , Wang Ziqi , Zhang Ting
Published: September 2023

Flood disasters occur frequently in semi-arid and sub-humid mountain watersheds, and their formation mechanism is affected by many factors, resulting in low simulation accuracy. The main purpose of this study is to evaluate the impact of adding actual river channel data on the accuracy of flood simulation. In order to obtain higher-resolution terrain data, an unmanned aerial vehicle (UAV) was used to survey the study area. Taking the Liulin Watershed in Xingtai City, Hebei Province as the research area, the HEC-HMS hydrological model and the HEC-HMS and HEC-RAS coupling model were constructed, respectively, to simulate 26 flood events during the period from 1982 to 2016. The results indicate that the coupled model can reflect the evolution process of river floods. When simulating certain major flood events, the percentage of flood peak error and Nash–Sutcliffe efficiency coefficient (NSE) have improved, such as the NSE of No. 160812 floods increasing from 0.9 to 0.95. However, the simulation accuracy of these two models for small floods in the watershed is relatively low. Future research should focus on how to accurately evaluate the parameter curve number (CN) of the watershed before rainfall and obtain more accurate runoff yield.
Aristóteles
Authors: Pacheco Gionatan Carlos
Published: September 2023

A presente tradução é do texto que John Burnet (1863-1928) leu para a Academia Britânica em 2 de julho de 1924. O texto foi publicado naquele mesmo ano nos Proceedings of the British Academy, e também integra a coletânea póstuma de escritos de Burnet, Essays and Addresses, publicada em 1929. O tema principal é acerca do estabelecimento de uma cronologia das obras de Aristóteles, cuja discussão é marcada pela, então, recente publicação de um livro de Werner Jaeger sobre Aristóteles.
O Mal da Morte e o Desafio do Tempo
Authors: Lima Cardoso André Luiz
Published: September 2023

Neste artigo, pretendemos explorar a tese comparativista sobre o mal da morte e como ela lida com o chamado Desafio do Tempo. De acordo com o comparativismo, a morte pode ser um mal na medida em que a pessoa estaria melhor, caso não tivesse falecido. No entanto, se ao morrer deixamos de existir, como a morte pode ser algo ruim? Mais especificamente, em que momento a morte prejudica o sujeito? Para responder a esta questão, primeiramente explicaremos no que consiste exatamente a tese comparativista, e como ela pode argumentar sobre algum valor prudencial da morte. Em seguida, explicaremos o que é o desafio do tempo e, por fim, analisaremos as respostas fornecidas pelos comparativistas ao problema. Buscaremos assim defender que o comparativismo pode não só dizer se uma morte é ruim, mas também o quão ruim pode ser para o indivíduo e, além disso, que essa abordagem propõe soluções plausíveis ao desafio do tempo.
A “metafísica silenciosa” no Tractatus Logico-Philosophicus
Authors: Guedes Paes Gabriel Gurae
Published: September 2023

Resumo: Lopes dos Santos, ao colocar o Tractatus Logico-Philosophicus no que denomina “tradição crítica”, mostra que Wittgenstein delimita o alcance da filosofia ao eliminar sua pretensão de ser um tipo de conhecimento que, como a ciência, possa formular proposições verificáveis sobre objetos. E Wittgenstein faz isso de modo distinto da crítica moderna à metafísica, pois elimina o sujeito do problema: não é preciso recorrer a faculdades subjetivas para fazer essa delimitação, mas apenas à linguagem na qual o pensamento se expressa. Por outro lado, na perspectiva da “tradição lógica”, há na mesma obra uma identificação entre a essência do “logos” que pode enunciar algo verdadeiro sobre o ser e do próprio ser do qual se fala nesse discurso. Nosso objetivo é destacar este vínculo com a “tradição lógica” para defender que, para além de uma “virada linguística”, há no Tractatus uma espécie de “metafísica silenciosa” que coloca problemas tais como o do sujeito e o da “essência” do mundo em seu correto lugar após passá-los pelo crivo da crítica.
DESENHOS DE UMA (QUASE) ARQUITETA E URBANISTA
Authors: Carvalho Ramon , Hammerschmitt da Veiga Alice
Published: September 2023

Este artigo é proveniente do Trabalho de Conclusão de Curso de uma estudante de Arquitetura e Urbanismo, escrito em primeira pessoa do singular. Traz inquietações e reflexões acerca do papel do desenho à mão livre para o ato de projetar e suas implicações na formação do/a arquiteto/a. Parte de um embasamento teórico-conceitual que aborda a questão do desenho como método de estudo e assimilação e apresenta, em formato de relato pessoal descritivo e imagético, um conjunto de experiências práticas de desenho realizadas ao longo do trabalho. Como resultado, identifica-se que: é preciso desenvolver uma expressividade própria para uma comunicação por meio do desenho; existe uma espécie de “diálogo interno do/com o desenhista” exteriorizado no papel; a notação gráfica pode ser considerada tanto uma forma de pensar como também um instrumento de apreensão do espaço e de suas características; as escolhas e intenções de cada pessoa/desenhista promovem diferentes modos de apreensão, que são demonstradas nos desenhos; e, por fim, que a realização deste trabalho gerou uma mudança significativa na compreensão e na postura da autora diante do “ser arquiteta”. Fundamentalmente, incorporou-se o desenho como meio de continuar aprendendo, apreendendo e desenvolvendo arquitetura.
Purchases as a Tool of Implementing State Policy
Authors: Berdnikov D. V.
Published: September 2023

The research deals with the system of state purchases, within which goals of state economic policy can be attained. The article studies and describes functions performed by the national system of state purchases. Special attention was paid to specific features of state purchases as a tool of influencing the macro-economic system controlled by government. Academic novelty of the research implies identification of various functional specificities of the process of planning and conducting state purchases, including their orientation to providing the state sector with necessary goods and services, influencing the macro-economic system of the country and document – administrative regulations of state purchase support. The author summarized the impact of state purchase realization on economic, legal, technological and innovation process in national economy and making-up the extended effective list of functions performed by state purchases. By analyzing statistic and report data of operators of the national system of state purchases and the Federal Service of State Statistics and figures of state purchase efficiency used by bodies of state authorities the author appraised the quality of the development of Russian economic policy in the field of state purchases.
Estimating Investment Project Revenue and Expenditure in Telecommunication Sector
Authors: Sysoev P. D.
Published: September 2023

The article studies the process of estimating investment project revenue and expenditure in telecommunication sector, illustrated by the public company ‘MTS’: key technologies of data transfer, their correlation with frequencies, structure of expenses on network building, approaches to estimation of project revenue. The author identified types of investment projects in view of different approaches to their evaluation: qualitative projects, which do not cause direct rise in profits and quantitative ones, whose estimation is possible by present value of cash flows. Advantages and drawbacks of the current approach to estimation of ‘MTS’ projects were formulated. The article shows technical and economic indices that can impact project efficiency and seriously change its recoupment. The author proposes to include costs of the network development not only of the access level but also of the level of aggregation and network core; to extend the horizon of planning network quality indices for the whole period of the project; to take into account costs of the future extension of network capacity during project implementation; to carry out modernization of the equipment in case of its technical support termination and output of components. With regard to discontinuity of network modernization steps it is necessary to account for the effect of growing quality of services above the target indicators.
Trends in Russian Logistics Development: Forecasts and Reality
Authors: Garnov A. P.
Published: September 2023

The goal of the article is to analyze forecasts and actual development of Russian logistics on the basis of concrete example, figures, quotations and references to research. Today Russian logistics is passing the stage of active development, however, there are a lot of challenges and problems that should be overcome. A key trend in Russian logistics development is digitalization and introduction of new technologies. According to the research conducted by the Committee on Logistics Development, in 2020 about 78% of logistical market participants in Russia supported introduction of digital innovation in their work. It can cut costs of transportation, raise process efficiency and improve the quality of customer service. However, Russian logistics has not reached its full potential in this field. Key problems are poor introduction of advanced information technologies and undeveloped digital infrastructure. According to the research published by the journal ‘Logistics and Managing Supply Chains’ in 2021 only 25% of logistic companies in Russia use systems of managing storehouses and transport on the basis of artificial transportation, which allows companies to cut delivery period and provide more efficient use of transport infrastructure. According to Rosgosstrakh research in 2020, the volume of multimodal transportation in Russia grew by 15% in comparison with the previous year. However, the Federal Agency on Air Service reports that the development of infrastructure for multimodal transportation is not sufficient. A lot of Russian regions face the absence of connections between various types of transport, which can cause delays and higher delivery cost. We should also point out that Russian logistics still encounters problems with logistical costs. According to the research of ‘The International Journal of Economics and Management’ in 2020 Russia takes the 92nd place by the index of logistical costs among 160 countries. The key reasons for high costs are inefficient use of resources and weak coordination among participants of the logistic chain. The development of Russian logistics supposes introduction of digital technologies, rise in the share of multimodal transportation and cutting logistic costs. Along with this it is necessary to overcome a number of problems, such as low level of digital infrastructure and weal coordination in the logistic chain. It will require joint efforts on the part of government, business and education institutions.
Non-Governmental Pension Support as an Element of Multitier Pension System
Authors: Balashova I. V. , Tereshchenko T. A.
Published: September 2023

Non-governmental pension funds (N-GPF) act as an important tool for resolving social problems in the field of pension support. Today 39 non-governmental pension funds work in Russia. All of them have got licenses for their operation. But before you transfer your money to non-governmental fund, you should study the list of acting organizations, identify the most stable ones and analyze their ratings. The article shows that top places in the rating by the volume of pension resources are taken by organizations, which store the biggest amounts of future pensioners’ money. Drivers of growth and N-GPF competitiveness support can become ecosystems. Amounts of such payments can testify to the efficiency of funds’ investment and thus to the quality of their work. Informing people about the system of non-governmental pension funds can cause a sharp rise in the number of their clients. According to the authors, in case employees of non-governmental pension funds visit large enterprises and provide their workers with necessary information about these funds, it could help attaint this goal. Employees of N-GPF should explain that the fund functions absolutely legally, all deposits are insured and information about fund profitability is open.
Diagnostic value of coronary flow acceleration measured by transesophageal echocardiography in coronary artery bypass graft surgery
Authors: Efremov S.M. , Novikov M.A. , Trofimov A.A. , Shmatov D.V. , Kamenskih M.S. , Zagatina A.V.
Published: September 2023

Background: Transesophageal echocardiography as a method of intraoperative coronary flow assessment is largely unstudied.Objective: To evaluate the potential of intraoperative transesophageal echocardiography in diagnosing proximal coronary artery stenoses, to reveal the correlation between stenoses found on coronary angiography and coronary flow velocity in the corresponding area measured by intraoperative transesophageal echocardiography, and to study how coronary flow velocity changes before and after coronary artery bypass graft surgery and how it is related to postoperative myocardial injury.Methods: Our prospective cohort study included 186 patients scheduled for coronary artery bypass graft surgery. All the patients underwent intraoperative transesophageal echocardiography: coronary flow velocity was measured in the area of its acceleration (proximal parts of the left coronary artery) before and after the surgery. Troponin I was measured on the first postoperative day.Results: The areas of accelerated coronary flow before the procedure were detected in the left main coronary artery (88 patients, 47.3%), left anterior descending artery (146 patients, 78.5%), and left circumflex artery (28 patients, 15.1%). ROC analysis showed that coronary flow velocity of >73 cm/s in the left main coronary artery and of >91 cm/s in the left circumflex artery was associated with a stenosis of 50% and 70% in the respective arteries measured by coronary angiography. Furthermore, an increase in coronary flow velocity in the left anterior descending artery or its decrease by 4 cm/s after coronary artery bypass graft surgery are predictors of a 10-fold increase in troponin I concentration in the postoperative period.Conclusion: Coronary flow velocity assessment during intraoperative transesophageal echocardiography can offer added value in detecting clinically significant coronary artery stenoses, while assessment of changes in velocity may predict perioperative myocardial injury.
Received 16 January 2023. Revised 16 May 2023. Accepted 31 August 2023.
Funding: The study did not have sponsorship.
Conflict of interest: The authors declare no conflict of interest.
Contribution of the authorsConception and study design: S.M. Efremov, M.A. Novikov, A.V. ZagatinaData collection and analysis: S.M. Efremov, M.A. Novikov, A.A. Trofimov, A.V. ZagatinaStatistical analysis: S.M. Efremov, A.A. TrofimovDrafting the article: S.M. Efremov, A.A. TrofimovCritical revision of the article: S.M. Efremov, M.A. Novikov, A.A. Trofimov, D.V. Shmatov, M.S. Kamenskih, A.V. ZagatinaFinal approval of the version to be published: S.M. Efremov, M.A. Novikov, A.A. Trofimov, D.V. Shmatov, M.S. Kamenskih, A.V. Zagatina
Three-dimensional (3D) land contour modeling using QGIS software on topography mapping in Buwit Village, Kediri District, Tabanan Regency, Bali
Authors: Yasada Gede , Setyono Evin Yudhi , Sutapa I Ketut
Published: September 2023

A topographical map is a map that contains information about the elevation of the land surface in a place to the mean sea level (Mean Sea Level), which is depicted by contour lines. Information from the coordinates and elevation of detailed land points as a result of land surveying can be used to create a three-dimensional model of the land surface on the map using the Quantum Geographic Information System (QGIS) software application. With a three-dimensional (3D) model, the objects on the map are seen more alive as they actually are in the field, so that analyzing a topographic map can be done more easily. To support these activities, three-dimensional (3D) land contour modeling was carried out with QGIS software on topographical mapping in Buwit Village, Kediri District, Tabanan Regency, Bali.
Az utánpótlás labdarúgással kapcsolatos szülői szerepek vizsgálata
Authors: Szalánczi Zoltán , Bácsné Bába Éva
Published: September 2023

Vizsgálatom alapját az adja, hogy a sport fejlődésének és a szektorba áramló tőkének köszönhetően az utánpótlássport immár nem csak a gyermekek szabadidejének hasznos eltöltését és az egészséges életmódra nevelés egy eszközét jelenti, hanem egy lehetőséget is a felnőttkori sportolói karrier megalapozására és ezzel együtt a későbbi biztos egzisztencia megteremtésére. Ahhoz, hogy a képzés hatásos és produktív legyen a sok összetevőből az egyik alapfeltétel a szülői támogatás megléte. A fiatalkori versenysport rengeteg kihívást jelent egy család számára és több aspektusból vizsgálva is befolyásolja az életüket. Kutatásom során megvizsgáltam, hogy bizonyos demográfiai változók tekintetében az utánpótlássport miként hat a szülőkre, milyen változásokat generál a családi életükben és arra is figyelmet fordítottam, hogy a családban milyen elvárások fogalmazódnak meg a sporttal szemben. A vizsgálat alapját egy online kérdőíves felmérésem adja, melyet több mint 700-an töltöttek ki a szülők közül országosan a labdarúgó utánpótlás nevelő egyesületek teljes vertikumában. Kutatásomból kiderült, hogy a korábbi témához köthető szakirodalmaknak megfelelően az általam vizsgált szülők életére is jelentős hatással van a gyermekük sportolása és különböző elvárásokat fogalmaznak meg azzal kapcsolatban, melyeket különböző szociális és demográfiai tényezők is befolyásolnak.
Kisvágóhíd szennyvízhasznosításának esővíz hasznosítással egybekötött lehetőségei
Authors: Hancz Gabriella
Published: September 2023

A tanulmány célja áttekinteni, hogy mobil kisvágóhídról származó szennyvíz milyen esetekben milyen mértékben, milyen céllal hasznosítható. A fenntarthatóság kritériumait szem előtt tartva azonosítom a lehetséges, egyben ésszerű kombinációit a technológiáknak, kiemelve és részletesebben bemutatva azokat, amelyek a szennyvíz hasznosítását és az esővíz hasznosítását is magukban foglalják. Ismertetem azokat a korlátozó tényezőket- helyszín adottságai, környezetvédelmi és egészségügyi szabályozás – amelyek meghatározóak abban, hogy egy konkrét telepítés során melyik alternatívára eshet a választás.
Substance use and sexual cognitive orientation as predictors of academic performance among pregnant adolescents in Nigeria
Authors: Otegbayo Bolajoko Elizabeth , Omar Noralina , Danaee Mahmoud , Atulomah Nnodimele O. , Aghamohamadi Nasrin
Published: September 2023

Despite extensive research on the subject, the persistent prevalence of unwanted pregnancies and school dropouts among teenage girls remains a significant concern. This study aims to elucidate the complex dynamics underlying substance use, adolescent psycho-cognitive predispositions, and academic achievement among pregnant teenagers in selected metropolitan areas of Nigeria. Using a cross-sectional study design, we enrolled 400 consenting pregnant teenagers from three chosen states in Nigeria (Niger state, Lagos, and Port Harcourt) between January and April 2021, employing the snowball sampling technique. Data were collected through a validated self-administered questionnaire and subjected to analysis using Structural Equation Modeling with Smart-Pls to illustrate path analysis representing the dynamics of the phenomenon. The findings revealed that substance use, including alcohol (β=-0.224, p<0.001) and psychoactive drugs (β=0.211, p<0.001), significantly influenced sexual-cognitive orientation, encompassing knowledge/perception (β=-0.229, p<0.001) and attitude (β=-0.171, p<0.001). Furthermore, sexual-cognitive orientation (β=0.443, p<0.001) and attitude (β=-0.168, p<0.001) significantly predicted academic performance. Substance use with abuse potential was found to impair the cognitive ability to make decisions regarding safe sex, and sexual activity negatively affected the academic performance of pregnant students. This study highlights the need for a multi-level approach, addressing individual and environmental factors, to facilitate positive lifestyle modifications related to sexual cognitive orientation and harm reduction, ultimately improving the academic performance of pregnant teenagers.
A QUALITATIVE STUDY ON THE DOCTRINE OF PRIVITY TO CIRCUMVENT ITS EFFECT ON SUBCONTRACTOR’S PAYMENT CLAIM
Authors: Yan See Zhi , Mohd-Danuri Mohd Suhaimi , Ismail Noorfajri , Mohamed Othman , Ismail Fadzida
Published: September 2023

In common law jurisdictions, the doctrine of privity has been criticised by the judiciary and academic commentators, particularly the second rule of doctrine, which states that a person who is not a party to the contract cannot sue on it to obtain promised performance, although the contract has been formed with the intention to benefit him. In certain circumstances, this rule may produce unfair and injustice result to the third party of a contract, as it prohibits the third party from enforcing the right to get benefits conferred on them. The doctrine of privity becomes relevant in the context of tendering procedures when subcontractors, who are not direct parties to the main construction contract, are involved. Hence, the aim of this paper is two-fold: to highlight the difficulties of the existing legal mechanism associated with privity rule and to suggest possible ways to circumvent the effect of the doctrine of privity on subcontractors’ payment claims in the Malaysian construction industry. By adopting the socio legal research approach, the impact of the doctrine of privity, the difficulties of the existing legal mechanisms, and the need for a possible law reform were examined. The findings were also validated by conducting semi-structured interviews with five construction law experts. Among others, the findings showed that enhancement to the existing legal mechanisms and statutory intervention can effectively circumvent the privity rule and protect the subcontractor’s right for the payment claim.
DETERMINANTS OF SPATIAL PLANNING FOR URBAN RESILIENCE IN THE ISLAMIC SOCIETY SETTING: A CASE STUDY OF BANDA ACEH, INDONESIA
Authors: Zuraidi Evalina , Zainol Rosilawati , Ahmad Yahaya , Achmad Ashfa
Published: September 2023

The paper identifies the determinants influencing spatial planning for urban resilience within the context of an Islamic society. Semi-structured interviews were conducted with relevant stakeholders in spatial planning and disaster management in the city of Banda Aceh, Indonesia to assess their attitudes, opinions and experiences in implementing spatial planning for urban resilience. Qualitative thematic analysis revealed dominant factors specific to the Islamic society in the city of Banda Aceh, which were then elaborated on and categorised into five major groups: spatial pattern, spatial structure, spatial culture, spatial-related non-physical factors and religious factors. The interviews affirmed the importance of religious and cultural factors in spatial planning for urban resilience within Islamic societies. The findings will provide an essential understanding of the need to enhance urban resilience against disasters in the urban planning process and incorporate aspects of local wisdom derived from religious and cultural values, as well as societal necessities, as a planning approach. Given the context-specific nature of this research, future researchers may consider doing a comparative case study in another city with similar characteristics.
THE IMPACT OF ONLINE SHOPPING ON SHOPPING CENTRES IN KLANG VALLEY, MALAYSIA
Authors: Mohd Adnan Yasmin , Liang Chin Kee , Razali Muhammad Najib
Published: September 2023

Real estate has been a spectator to technology disruption for the past few years as many activities that used to be mediated by physical spaces within buildings are presently being shifted to virtual space. Markedly, this is the case in shopping as brick-and-mortar retailers are being disrupted by e-commerce. This study’s premise is that it is not clear whether the emergence of online shopping would transform the physical retail property sector in Malaysia. To gauge the impact of the disruption on the physical space, this study conducted a survey among the shoppers in Klang Valley, Malaysia to determine the preference of shoppers to shop virtually or in the physical spaces at shopping centres. From the findings, it is found that the virtual space is not identified as an immediate and direct threat to physical space by shoppers. The synergies between the virtual space and physical space have to be explored so that the existing physical spaces can be designed to ensure sustainability with shoppers’ preferences.
Industry contributions to productivity growth in U.S. manufacturing: an application of alternative output concepts
Authors: Eldridge Lucy P. , Powers Susan G.
Published: September 2023

To understand the performance of the U.S. manufacturing sector, in this article, we explore the performance of individual industries. We first use the U.S. Bureau of Labor Statistics published data to look at the influence of industries on sector-level performance and total factor productivity (TFP) growth. The underlying dynamics of production in any given industry determine its influence on the sector as a whole. Both an industry’s share of output and its individual TFP growth vary over time, and these changes jointly determine the industry’s contribution to performance in the manufacturing sector. Next, we trace the contribution of industries to manufacturing sector TFP by using three alternative output concepts—value-added output, sectoral output, and gross output. We examine the differences in industry contributions that result from the use of the alternative output measures, over 2000–21 and three different business cycles (2000–07, 2007–19, and 2019–21). We show that one must carefully deliberate before selecting a value-added-output, sectoral-output, or gross-output framework for TFP and contribution analysis.