bluuebunny/crossref_metadata_2025 huggingface dataset:
KESEJAHTERAAN SPIRITUAL DAN MINDFULNESS PADA MAJELIS SAHABAT SHALAWAT
Authors: Fourianalistyawati Endang
Published: February 2018

Spiritual wellbeing in psychology is used to discuss the process of achieving the spiritual condition of individual. Spiritual wellbeing is a concept of innate state. It has an element of motivation or encouragement to find a goal in life that is dynamic and subjective, and it focuses on a certain uniqueness which then it is believed as a truth. One way to improve spiritual wellbeing is through dhikr activities, which is frequently used as one of the psychotherapy in Islam. In dhikr activities, individual is asked to perform activities such as realize the breath that come in and out of his body during the activities. That condition is fundamental in mindfulness practice. Mindfulness is defined as the ability to give attention to self the way it is without judgement, and receive all the thoughts that arise in the moment. Researcher was interested to know more about the correlation between spiritual wellbeing and mindfulness on an assembly of shalawat friends members, who regularly performed shalawat everyday. The data obtained 89 subjects that could be processed of 100 questionnaires that were filled. This research method was quantitative and the design of the study was correlational. Data analysis was performed using bivariate analysis using Pearson correlation. Based on the results of data analysis, it could be inferred that there was a relationship between the spiritual wellbeing and mindfulness on assembly of shalawat friends, with a value of R = 0.388. It was concluded that the high value of spiritual wellbeing was followed by the high value of mindfulness.
KHUSNUDZON DAN PSYCHOLOGICAL WELL BEING PADA ORANG DENGAN HIV/AIDS
Authors: Uyun Qurotul , Siddik Irman Nuryadin
Published: February 2018

The aims of this research is determine the relation between khusnudzon and psychological well being in people living with HIV / AIDS. The hypothesis in this research is there is positive relation between khusnudzon psychological well being in people living with HIV / AIDS. To test the hypothesis of the research, researchers collecting data using a scale of psychological well being adapted from a Ryff’s scale (1989) and adapted khusnudzon scale of Dewi’s scale (2015) is based on the theory from Rusydi (2012). The scale distributed to 55 people living with HIV/ AIDS who are the members of the VP foundation. Correlation analysis show the coefficient of r = 0.543 with significance (p) <0,01 so that hypothesis is accepted.
Uçucu madde bağımlısı bir gençte görülen atrial flutter
Authors: BOZABALI Sibel , ÜLGER Zülal , LEVENT Ertürk , ÖZYÜREK Arif Ruhi
Published: February 2018

İnhalan bağımlılığı, dünya genelinde özellikle genç jenerasyonu ilgilendiren önemli bir sosyal problemdir. Ucuz ve kolay erişilebilmeleri nedeniyle yapıştırıcı maddelerin keyif verici madde olarak inhale edilmelerine oldukça sık rastlanır. Daha önce sağlıklı olan 16 yaşındaki erkek çocuk, karın ve göğüs ağrısı nedeniyle acil servise başvurdu. İzlemi sırasında yoğun bakım ihtiyacı gerektiren semptomatik atriyal flutter gözlendi. Olgunun yoğun miktarda uçucu madde kullandığı öğrenildi. Yapıştırıcı madde bağımlılığının en korkulan sonucu özellikle ventriküler aritmilere bağlı olarak ortaya çıkan ani ölümdür. Burada yapıştırıcı madde inhalasyonuna bağlı olarak ortaya çıkan ve ilk kez yayınlandığı düşünülen atriyal flutterlı bir olgu sunulmuştur. Farklı aritmiler ve myokard hasarı gözlenen genç erişkinlerde inhalan madde kullanımı özellikle sorgulanmalıdır.
Enalapril ve essitalopram ile özkıyım girişimi sonrası gelişen rabdomiyoliz
Authors: Oğuz Sinan , Tuygun Nilden , Karacan Can Demir
Published: February 2018

Rabdomiyoliz, kas nekrozu sonucu kas içi içeriğin kan dolaşımına çıkması ile gelişen klinik bir sendromdur. En önemli komplikasyonu akut böbrek hasarıdır. Rabdomiyoliz çok değişik etiyolojik faktörlere bağlı olarak ortaya çıkabilir. En sık nedenler ise travma, aşırı egzersiz, inflamatuar kas hastalıkları, uzun süren hareketsizlik, elektrolit dengesizlikleri ve ilaç toksisitesidir. İlaç zehirlenmelerinde rabdomiyoliz ve olası komplikasyonları açısından dikkatli olunmalıdır. Enalapril elektrolit dengesizliğine neden olarak, essitalopram ise serotonin sendromuna yol açarak olarak rabdomiyolize neden olabilir. Bu yazıda elektrolit bozukluğu veya nöroleptik sendrom gelişmeden, özkıyım amacı ile enalapril ve essitalopram alımı sonrası ılımlı rabdomiyoliz gelişen, öncesinde sağlıklı on beş yaşındaki bir kız çocuğu sunulmuştur. İlaçlar farklı mekanizmalar ile rabdomiyolize neden olabilir. Bazı ilaçların önemli klinik değişliklere yol açmadan da rabdomiyolize neden olabileceği akılda tutulmalıdır.
İshal ile başvuran bir medüller tiroid kanseri olgusu: MEN 2B sendromu
Authors: Almuradova Elvina , Yıldırım Şimşir İlgın , Erdoğan Mehmet , Çetinkalp Şevki , Saygılı Füsun , Özgen Ahmet Gökhan
Published: February 2018

Multipl endokrin neoplazi tip 2B (MEN 2B) otozomal dominant geçişli, medüller tiroid kanseri, feokromositoma, marfanoid görünüm ve mukozal nöromlarla karakterize bir sendromdur. Hastalık zamanı esas semptomlar; hipertansiyon, aşırı terleme, ishal, cilt lezyonları, boyun kitlesine bağlı kompressiyon, hiperkalsemiye bağlı poliuri, polidipsi, depresyon, böbrek taşı ve gastroezofajial reflüdür. Bu yazıda, pek çok kez tek bir diyare şikayeti nedeniyle hospitalize edilse de tanısı konulamamış, kliniğimize başvurduğunda bilateral feokromositoma, medüller tiroid kanseri, marfanoid görünüm, mukozal nörinomlar, sırtta paragangliomlar nedeniyle MEN 2B sendromu tanısı alan bir olgu sunulmaktadır.
Different types of trochlear apparatus calcification: Evaluation with multidetector computed tomography (MDCT)
Authors: Bülbül Erdoğan , Yazıcı Alper , Yanık Bahar , Demirpolat Gülen
Published: February 2018

Aim: Trochlear apparatus calcification (TAC) can be an incidental finding in multidetector computed tomography (MDCT) scans. TAC may be misdiagnosed as a foreign body especially in trauma patients. In this study we aim to determine the incidence and types of TAC with cranial and paranasal MDCT scans.Materials and Methods: Consecutive 452 MDCT scans were evaluated retrospectively. Repeated exams and patients with orbital wall fracture history were excluded. CT scans were obtained by a 64-slice scanner with 0.5 mm slice thickness. Reformatted and three-dimension volume rendered images in bone window were used to assess the calcification presence and type.Results: Four hundred forty-one MDCT exams included to study. TACs detected in 31 (7.5%) subjects. TAC was unilateral in 24 (77.4%) and bilateral in seven (22.6%) subjects. There was no significant correlation with aging (p=0.681) and between genders (p=0.808). “Dot-like” TAC was the most common type (n=12, 31.6%). The other types were “inverted-U” (n=11, 28.9%), “linear” (n=8, 21%), “comma” (n=6, 15.6%), respectively. Eight (21%) of TACs were attaching the orbital wall, mostly in “comma” type.Conclusion: The TAC incidence in our study was compatible with literature. Four different types of TAC, including, “dot-like”, “inverted U”, “linear” and “comma” types detected. TACs were usually discrete from the orbital wall however they were occasionally attached. “Linear” type TAC and attachment to orbital wall described for the first time in this study. Knowledge of the TAC appearance may be helpful to differentiate TACs from foreign bodies.
Reaching High-Need Youth Populations With Evidence-Based Sexual Health Education in California
Authors: Campa Mary I. , Leff Sarah Z. , Tufts Margaret
Published: February 2018

Objectives. To explore the programmatic reach and experience of high-need adolescents who received sexual health education in 3 distinct implementation settings (targeted-prevention settings, traditional schools, and alternative schools) through a statewide sexual health education program.

Methods. Data are from youth surveys collected between September 2013 and December 2014 in the California Personal Responsibility Education Program. A sample of high-need participants (n = 747) provided data to examine the impact of implementation setting on reach and program experience.

Results. Implementation in targeted-prevention settings was equal to or more effective at providing a positive program experience for high-need participants. More than 5 times as many high-need participants were served in targeted-prevention settings compared with traditional schools. Reaching the same number of high-need participants served in targeted-prevention settings over 15 months would take nearly 7 years of programming in traditional schools.

Conclusions. To maximize the reach and experience of high-need youth populations receiving sexual health education, state and local agencies should consider the importance of implementation setting. Targeted resources and efforts should be directed toward high-need young people by expanding beyond traditional school settings.
Teknologi Penyimpanan Umbi Kentang (Solanum tuberosum L.) Var. GM-05 dengan Rekayasa Pencahayaan untuk mempertahankan Kesegarannya
Authors: Broto Wisnu , Setyabudi Dondy A , Sunarmani NFN , Qanytah NFN , Jamal Irpan Badrul
Published: February 2018

Kondisi penyimpanan menjadi kata kunci untuk meningkatkan daya simpan umbi kentang GM-05 dengan mutu segar yang terjaga.
Kentang segar GM-05 dalam penelitian ini diperoleh dari Kebun Percobaan Balai Penelitian Sayuran, Lembang dan dipanen pada umur
90 Hari Setelah Tanam (HST). Umbi kentang dengan bobot masing-masing 30 kg dikemas dalam karung rajut, disimpan pada kondisi
(1) ruangan gelap, (2) ruangan dengan pencahayaan 100-500 lux/lilin, dan (3) dihamparkan sebagai kontrol. Penyimpanan dilakukan
pada suhu ambient, 20, dan 10oC. Pengamatan dilakukan setiap 2 (dua) minggu sekali selama 3 bulan penyimpanan. Parameter yang
diamati meliputi: susut bobot, kadar air, kadar protein, kadar karbohidrat, kadar lemak, kadar amilosa, kadar abu, dan tekstur. Rancangan
percobaan menggunakan rancangan acak lengkap tersarang dengan ulangan tiga kali dan signifikansi beda nyata terkecil pada taraf
5%. Hasil penelitian menunjukkan bahwa penyimpanan dalam ruang gelap maupun yang dengan pencahayaan 100-500 lux/lilin suhu
10 oC memberikan susut bobot dan laju penurunan kadar air terendah dibandingkan perlakuan lainnya. Kadar karbohidrat, kadar abu,
dan tekstur tidak terpengaruh dengan semua perlakuan penyimpanan. Penurunan kadar lemak dan amilosa umbi kentang melambat
hingga masing-masing sebesar 0,14% dan 4,42% terjadi pada penyimpanan dalam ruang gelap maupun yang dengan pencahayaan pada
suhu 10 oC. Kadar protein meningkat hingga pada kisaran 1,51%. Penyimpanan suhu 10oC dengan kondisi gelap ataupun pencahayaan
100-500 lux/lilin merupakan metode penyimpanan kentang GM-05 terbaik karena mampu mempertahankan mutu dan kesegarannya.
Prevalence and Clinical Characteristics of the Restless Legs Syndrome (RLS) in Patients Diagnosed with Attention Deficit Hyperactivity Disorder (ADHD) in Antioquia
Authors: Sierra Montoya Ana Carolina , Mesa Restrepo Sandra Catalina , Cuartas Arias Jorge Mauricio , Cornejo Ochoa William
Published: February 2018

Introduction: Attention Deficit Hyperactivity Disorder (ADHD) is the most common behavioral issue for children. One of the sleeping disorders most frequently related to ADHD is the Restless Legs Syndrome (RLS), characterized by an irresistible urge to move the legs, something that is generally associated with paresthesias and motor restlessness. The prevalence rate of RLS in children diagnosed with ADHD is close to 18%, but in Colombia, these cases have been hardly studied. Objective: To determine the frequency of RLS, in children with ADHD. Methods: A cross-sectional study, filled out by parents of children diagnosed with ADHD, were analyzed. This questionnaire contained clinical criteria for classifying ADHD according to the DSM-IV, as well as diagnostic criteria for RLS by the National Institutes of Health (2003). Results: A predominance rate of 65.6% in combined ADHD was observed in children with RLS criteria. Upon carrying out an exploratory data analysis, it was found that having a family history of RLS and belonging to the middle or low socioeconomic strata are conditions associated with the presence of RLS in children with ADHD, with a significant p (p < 0.000) and a PR of 4.47 (3.16-6.32). Conclusions: The prevalence of RLS was similar to the findings of other clinical investigations. However, it highlights new prevalence values in relation to the comorbidity between ADHD and RLS, suggesting the need for new clinical and therapeutic alternatives amidst the presence of both syndromes.
Structure and profitability in the banking sector
Authors: Simatele Munacinga , Mishi Syden , Ngonyama Nomasomi
Published: February 2018

The relationship between profit and bank market structure continues to raise questions amongst both policy makers and researchers. While some evidence supports a positive relationship between market structure, competition and profitability, other evidence seems to support the fact that profitability and related market share result from efficiency. Moreover, extant literature on South Africa is conflicting and seems to contradict anecdotal evidence. While some studies point to a competitive environment despite concentration, others suggest that concentration in the banking sector is harmful. Prosecution of banks for uncompetitive behavior also casts doubt on the conclusion that the South African banking sector is competitive. This paper examines the relationship between structure and conduct in the South African banking sector. Using the Berger (1995) discriminating tests, the effect of industry concentration, market share and efficiency on three measures of profitability is estimated on a panel of 11 South African banks for data between 1994 and 2016. The results show that concentration affects conduct. The profit-structure relationship is dominantly explained by the structure conduct hypothesis and partly by the efficient scale hypothesis. These results suggest that policy which discourages concentration and promotes competition in the banking sector is socially beneficial.
The concept of distribution of powers among accounting entities considering modernization strategy in the public sector of Ukraine
Authors: Khorunzhak Nadiia , Karmaza Oleksandra , Kurylo Mykola , Javadov Hikmat
Published: February 2018

Reformation of accounting in the public sector of Ukraine, which was aimed at adapting to the international standard requirements, led to some inconsistencies related to the division of powers of its subjects. In this regard, it became relevant to study not only the methodology transformation, but also to optimize the powers of accounting subjects. Avoiding duplication of functions will harmonize the accounting system, simplify the mechanisms of data formation and increase the effectiveness of making managerial decisions. The application of the approaches for differentiating the powers of the subjects of accounting and the links between them will improve the quality and informational outgoing credentials, which are subsequently used in making managerial decisions. The study results can serve as the basis for developing a comprehensive information management system for public sector entities aimed at improving their performance.
Effects of morphological change on fluvial flood patterns evaluated by a hydro-geomorphological model
Authors: Hou Jingming , Han Hao , Li Zhanbin , Guo Kaihua , Qin Yi
Published: February 2018

High aggradation and degradation in a river induced by the last flood event will raise and decrease the risk of an upcoming flood event, respectively. To quantitatively investigate this effect, a two-dimensional (2D) hydrodynamic model coupled with a sediment transport the river-bed evolution models is developed. After being validated against two experimental benchmark tests, the model is applied to simulate the effects of the morphological change on flood patterns. It is found in two experimental scale tests that bed evolution may have substantial influence on water level, which is directly related to flood risk extent. In the application of the model computing a realistic flood event in Bayangaole Reach of Yellow River, the results show that the water surface level becomes lower for an upcoming flood event with the same hydrograph, indicating the flood risk considerably decreases in the next flood event. The effect of a perturbed bed therefore could be of significance for fluvial flood over a movable bed and therefore to flood risk management.
Algorytmiczność biologii
Authors: Uchmański Janusz
Published: February 2018

Matematyczność fizyki jest zjawiskiem, którego obecność jest dla nas zaskakująca, ale które pozwala nam na poznanie przyrody poprzez analizę matematycznych struktur ją opisujących. Dotyczy to jednak wyłącznie fizyki. Stopień matematyzacji biologii jest niewielki, a próby użycia języka matematyki sprowadzają się w istocie do stosowania w biologii metod matematycznych, których używa się do opisu układów fizycznych. Jest prawdopodobne, że popełniamy w ten sposób błąd przypisując układom biologicznym cechy, których nie posiadają. Pojawiają się głosy, że biologia wymaga nowych metod matematycznych dostosowanych do jej potrzeb, nie znanych z fizyki. Sądzę jednak, że z uwagi na specyfikę złożoności, którą reprezentują układy biologiczne, zamiast o matematyczności biologii należy mówić o jej algorytmiczności. Jako przykłady algorytmicznego podejścia można przywołać tak zwane modele osobnicze używane między innymi do opisu dynamik populacji lub metody modelowania fraktalnego stosowane do opisu złożoności geometrii i jej dynamiki skomplikowanych struktur biologicznych, takich jak na przykład drzewa.
Możliwość zastosowania teorii decyzji do zagadnień etycznych w ujęciu Klemensa Szaniawskiego
Authors: Majewska Lucyna
Published: February 2018

Klemens Szaniawski, mimo że kojarzony z filozofią nauki i logiką, w swoich rozważaniach zajmuje się również teorią decyzji i wskazuje na jej związek z zagadnieniami etycznymi. Wychodząc od pojęciowego i językowego powiązania między teorią decyzji a etyką, poszukuje dalszych ich relacji, które poddaje analizie.    W artykule pokazano przydatność twierdzeń teorii decyzji nie tylko do analizy zagadnień etycznych, ale także wyborów działania (podejmowania decyzji), które ściśle są związane z podmiotem etycznym. Po pierwsze, wskazano, że pojęcie racjonalności jest istotnym elementem wiążącym proces decyzyjny z etyką. Po drugie, pojęcie decyzji zawiera dwa elementy: wybór działania i postanowienie jego realizacji. Decyzja jest zrelatywizowana do celu, cel zaś determinuje działanie podmiotu, a sam wybór uwzględnia przekonania i wartościowanie decydenta. Po trzecie, rozumienie pojęcia decyzji wiąże się z podmiotem, który posiada pewien charakter i formuje go podczas podejmowania decyzji. Co więcej, w konkretnych decyzjach podmiotu, uwidoczniają się jego cele, środki i motywy. Dlatego włączenie teorii decyzji do analizy osobowości podmiotu i definiowania tożsamości pozwala na uzyskanie wielostronnej wiedzy na temat człowieka.    W nowym spojrzeniu na zagadnienie całego procesu decyzyjnego wskazano na możliwość pragmatycznego zastosowania pojęć teorii decyzji w etyce. By określić przydatność aparatury pojęciowej teorii decyzji w praktyce, posłużono się przykładami zaczerpniętymi z nauk prawnych i medycyny.
John Rawls: uzasadnienie praktyczne koncepcji sprawiedliwości i refleksyjna równowaga
Authors: Kędziora Krzysztof
Published: February 2018

W artykule autor podejmuje dwie istotne kwestie dla zrozumienia natury uzasadnienia praktycznego. Pierwsza z nich to wyjaśnienie natury uzasadnienia praktycznego jako porozumienia między obywatelami społeczeństwa demokratycznego co do warunków (zasad) działania politycznego. Druga z nich dotyczy wyjaśnienia tego, czym jest refleksyjna równowaga.
„Mieszkańcy gwiazd” według Karla Rahnera
Authors: Rodzeń Jacek
Published: February 2018

W swojej ogromnej spuściźnie piśmienniczej Karl Rahner (1904–1984) nie pominął zagadnienia istnienia rozumnych istot pozaziemskich. Są to jednak wypowiedzi nieliczne, fragmentaryczne i rozproszone. Pomimo tego dają one wyrazisty i oryginalny obraz filozoficzno-teologiczny tego zagadnienia. Kwestię potencjalnych inteligencji pozaziemskich Rahner przedstawia na tle metafizycznego ujęcia kosmosu jako nieustannie stającej się i autotranscendującej rzeczywistości. W jego opinii kosmos w swoich prawach fizycznych i zgodnie z celowym zamysłem jego Stwórcy zorientowany jest nie tyle w stronę człowieka (antropocentryzm), lecz podmiotów cielesno-duchowych (podmioto-centryzm). W tej perspektywie realna staje się możliwość powstania także innych, oprócz człowieka, istot rozumnych. Z punktu widzenia teologii są one według Rahnera tak samo otwarte na samoudzielającego się Boga-Trójcy w Logosie-Chrystusie-Zbawcy (chrystocentryzm) jak ludzie.
Lawrence M. Krauss o powstaniu Wszechświata z nicości. Czy współczesna fizyka rozwikłała zagadkę istnienia Wszechświata?
Authors: Mrozek Jarosław
Published: February 2018

Jak i dlaczego powstał Wszechświat? Problem z naukowym wyjaśnieniem istnienia Wszechświata polega na tym, że zakłada ono pewną fizyczną przyczynę jego istnienia. Ale jakakolwiek fizyczna przyczyna Wszechświata musi być częścią Wszechświata, którego zaistnienie ma wyjaśnić. Z tego powodu każde czysto naukowe wyjaśnienie istnienia Wszechświata jest skazane na zapętlenie. Być może żadna teoria naukowa nie może przerzucić mostu pomiędzy absolutną nicością a istniejącym już Wszechświatem.Okazuje się jednak, że gdy metafizyczne pytanie typu: dlaczego istnieje Wszechświat? zamienimy na „bardziej naukowe”: w jaki sposób powstał (mógł powstać) Wszechświat?, to mamy szansę na gruncie fizyki przedstawić współczesną wersję „historii” powstania Wszechświata. Kosmolog Lawrence M. Krauss twierdzi, że w tym celu wystarczy porzucić mętne – z punktu widzenia fizyki – pojęcie absolutnej nicości i za punkt wyjścia uznać fizyczną próżnię. Ponieważ – jak wynika z mechaniki kwantowej – kwantowa próżnia to dalece nie to samo co nicość metafizyczna (według mechaniki kwantowej czas i przestrzeń mogły powstać spontanicznie, a nawet, być może, spontanicznie powstały same prawa natury), możliwe jest – w świetle naszej współczesnej wiedzy – powstanie Wszechświata z „niczego”.
Macrophage Migration Inhibitory Factor - A Favorable Marker in Inflammatory Diseases?
Authors: Hertelendy Johannes , Reumuth Georg , Simons David , Stoppe Christian , Kim Bong-Sung , Stromps Jan-Philipp , Fuchs Paul C. , Bernhagen Jurgen , Pallua Norbert , Grieb Gerrit
Published: February 2018

Background:

Macrophage migration inhibitory factor (MIF) was firstly described in the
1960s as a pleiotropic cytokine affecting a variety of immune cells. Different physiological functions
mainly involving inflammatory reactions such as chemokine-like function and regulating systemic
stress responses have been reported.

Objective:

In several clinical studies the use of MIF as a biomarker has been investigated promising
support for diseases with an inflammatory aspect such as sepsis, systemic infections and autoimmune
diseases. This article in detail reviews clinical data and evaluates the function as biomarker focusing
on inflammatory and autoimmune diseases.

Conclusion:

Recent studies suggest MIF to be a marker for different inflammatory diseases and might
serve as therapeutic target in the future.
Peptides and their Metal Complexes in Neurodegenerative Diseases: from Structural Studies to Nanomedicine Prospects
Authors: Trapani Giuseppe , Satriano Cristina , La Mendola Diego
Published: February 2018

Background:

The metal ions dyshomeostasis is increasingly recognized to play a crucial role
in the development of aging-related neurodegenerative diseases. Metal trafficking in the brain is related
to proteins regulating both uptake and efflux of metals in neurons. Different pathways may occur, depending
on specific binding features of metallo-protein complexes. In particular, copper, zinc and iron
are recognized to influence the biochemistry of proteins involved in neurodegeneration (for instance Aβ
and α-synuclein), as well as those playing a crucial role in neuronal development and efficiency (neurotrophins).
Nowadays the application of peptide-based drugs is widespread for different pathologies,
but the short lifetime in vivo due to proteolysis and other shortcomings still limit their use.

Methods:

A structured search was performed about the state of the art on: i) peptidomimetic approaches
used to obtain peptides mimicking the metal binding activities of proteins involved in neurons
survival, ii) peptide-based nanostructures, as promising biomaterials in tissue engineering and substrates
for neurites outgrowth and synapses formation.

Results:

Recent developments on metal-binding peptides and peptide nanostructures for therapeutic
application in neurodegenerative diseases are reviewed, showing as metal ions interaction may affect
structural and biological properties of different proteins involved in neurodegenerative diseases.

Conclusion:

This review provides a survey on peptides able to mimic some biofunctional activities of
the whole protein, e.g., the binding features to metal ions, thus highlighting their promising potentialities
as new, more effective, therapeutics. The integration of such peptides into multifunctional nanoplatforms
can be a smart route for the development of biomaterials scaffolds and nanomedicine applications.
Antibacterial Strategies for Wound Dressing: Preventing Infection and Stimulating Healing
Authors: Li Zhengwen , Knetsch Menno
Published: February 2018

Wound management is an important and increasing global issue. Infection of a wound can cause a
delay in wound healing and pain, but also more serious complications like tissue necrosis or even sepsis, which
can lead to loss of tissue, limbs or life. Antibacterial agents have been introduced into wound infection care. In
this review, we provide an insight into the current antibacterial strategies of wound dressings, including wound
infection process, antibacterial agents, and controlled drug release systems. We also emphasize the development
of intelligent wound dressing and introduce a promising research direction.
Predictive and Descriptive CoMFA Models: The Effect of Variable Selection
Authors: Sepehri Bakhtyar , Omidikia Nematollah , Kompany-Zareh Mohsen , Ghavami Raouf
Published: February 2018

Aims & Scope: In this research, 8 variable selection approaches were used to investigate
the effect of variable selection on the predictive power and stability of CoMFA models.

Materials & Methods:

Three data sets including 36 EPAC antagonists, 79 CD38 inhibitors and 57
ATAD2 bromodomain inhibitors were modelled by CoMFA. First of all, for all three data sets,
CoMFA models with all CoMFA descriptors were created then by applying each variable selection
method a new CoMFA model was developed so for each data set, 9 CoMFA models were built.
Obtained results show noisy and uninformative variables affect CoMFA results. Based on created
models, applying 5 variable selection approaches including FFD, SRD-FFD, IVE-PLS, SRD-UVEPLS
and SPA-jackknife increases the predictive power and stability of CoMFA models significantly.

Result & Conclusion:

Among them, SPA-jackknife removes most of the variables while FFD retains
most of them. FFD and IVE-PLS are time consuming process while SRD-FFD and SRD-UVE-PLS
run need to few seconds. Also applying FFD, SRD-FFD, IVE-PLS, SRD-UVE-PLS protect CoMFA
countor maps information for both fields.
Importance of Improving Resilience in Teaching-Learning Process of Students with Disabilities
Authors: Macías Eleticia Isabel Pinargote , Cedeño Hernán Andrés Cedeño , Chávez Gabriela Monserrate Romero
Published: February 2018

The objective of the work focuses on determining the importance of resilience in the teaching-learning process of students with disabilities at the Technical University of Manabí, for this purpose an exploration is carried out to verify the criterion on this concept students group. The work deals with contemporary contextual aspects that may favor a psychosocial approach to resilience. The article is based on qualitative research based on the qualitative interpretative-hermeneutic paradigm. The theoretical referents were consigned from the bibliographic review, with the purpose of confronting them with the empirical phase that allowed to unravel the individual representations of the interviewees about the resilience. The results of the research show that resilience is widely known, although an important bias is maintained in its representation related to a more individual than the social view, which could limit its influence as a pedagogical factor.
Rutucharya - A Seasonal Regimen
Authors: Junjarwad Geeta J.
Published: February 2018

A healthy life is a wish of everybeing since antiquiety. Ayurveda is the science of life with the aim of attaining health and curing diseases of ill. Ayurveda describes seasonal regimen for maintainance of health. In every Ritu, climate is different so the condition of Dosha is also different. So to maintain the equation of Dosha, one should follow the regimen, which are explained in Ayurveda so that one can prevent disease. Hemanta Ritu is a very pleasant Ritu, coming in Dakshinayana, moon is very powerful than sun, sweet taste are predominant in Ritu, so the strength of person enhances during the period.
Management of Diabetic Foot Ulcer by Nishadi Yoga Avachoornana - A Case Study
Authors: Kumar R. Chiranth , Fathima Syeda Ather
Published: February 2018

Diabetes is considered as ‘ice burg’ of diseases as only 1/3rd of its manifestations can be made out clinically, though the exact cause is not known following are the theories put forth to explain diabetes mellitus - Genetic factor, Life style disorder, Autoimmune cause. Slight injury to glucose laden tissue will cause infection which is precipitated by an ulcer and it tends to a state of non - healing. Main stay of treatment includes antibiotics, debridement, local wound care. Inspite of these treatments there is less reduction in the statistics of diabetic foot complications and amputations. In Sushrutha Samhitha we get the most scientific approach for the management of Vrana, where Sushrutha has mentioned 60 Upakrama’s (modalities of treatment) of which Avachoornana (dusting) is one modality, seen to be effective in the management of diabetic non healing ulcers (Madhu Mehaja Dusta Vrana).
JAYANTI DALAL’S THE DARKNESS DESCENDS (JAGMOHANE SHU JOVU?): A DISTRESS OF BLINDNESS AND COMPROMISING THE SELF
Authors: Chaudhari Bhagvanhai H.
Published: February 2018

Jayanti Dalal was an eminent playwright, critic and prose writer of Gujarati literature. His sense of employing experiments with form and techniques made him somewhat distinct writer. All his literary works are thought-provoking manifesting unique characteristics through analysis of human perspective. The story The Darkness Descends (Jagmohane Shu Jovu?) focuses on the feelings of Jagmohan, the hero of the story who loses his eyesight. The writer seems to reveal the truth that one should live with rational honesty. He aims at understating the human mind. The writer constructs a story through psychological truth, which doesn’t seem mere a fancy tale. The writer has conducted an experiment of a ‘story within story’ by using comparable Japanese story. The writer applies here his sense of experimentation with a view to comparing and analyzing the self with the others.
VICTIM EMANCIPATION THROUGH COMPENSATION: A STUDY WITH SPECIAL REFERENCE TO SECTION 357 OF CRPC
Authors: Gagneja Shaveta
Published: February 2018

One area which is totally overlooked is the plight of the victims. It is a recent trend in the sentencing policy to listen to the wailings of the victims. Rehabilitation of the prisoner need not be by closing the eyes towards the suffering victims of the offence. A glimpse at the field of victimology reveals two types of victims. The first type consists of direct victims, i.e. those who are alive and suffering on account of harm inflicted by the prisoner while committing the crime. The second type comprises of indirect victims who are dependant of the direct victims of crime who undergo suffering due to deprivation of their bread winner.
Community Volunteer Support for Families With Young Children: Protocol for the Volunteer Family Connect Randomized Controlled Trial (Preprint)
Authors: Grace Rebekah , Kemp Lynn , Barnes Jacqueline , Elcombe Emma , Knight Jennifer , Baird Kelly , Webster Vana , Byrne Fiona
Published: February 2018

BACKGROUND

Use of community volunteers to support vulnerable families is a widely employed strategy with a long history. However, there has been minimal formal scientific investigation into the effectiveness of volunteer home visiting programs for families. There is also a need for research examining whether volunteer home visiting leads to improved outcomes for volunteers.

OBJECTIVE

The objective of this paper is to describe the research protocol for a pragmatic randomized controlled trial (RCT) of the Volunteer Family Connect intervention, a volunteer home visiting program designed to support families of young children who experience social isolation or a lack of parenting confidence and skills. The project is being conducted in partnership with 3 leading not-for-profit organizations, designed to contribute to the body of evidence that informs decisions about appropriate family support services according to the level of need. It is the first study to examine outcomes for both the families and the volunteers who deliver the service.

METHODS

The RCT is being conducted in 7 sites across Australia. We aim to recruit 300 families to the study: 150 control (services as usual) and 150 intervention (services as usual + volunteer home visiting) families. Intervention families will receive the service for 3-12 months according to their needs, and all participants will complete 6 data collection points over 15 months. A minimum of 80 volunteers will also be recruited, along with a matched community comparison group. The volunteers will complete 3 data collection points over 12 months. Primary outcomes include community connectedness and parenting competence. Secondary outcomes include parent physical and mental health; general parent well-being; parent empowerment; the child-parent relationship; sustainability of family routines; child immunization; child nutrition or breastfeeding; number of accidental injury reports; and volunteer health, well-being, and community connectedness.

RESULTS

This effectiveness trial was funded in 2016, and we aim to complete data collection by the end of 2018. The first results are expected to be submitted early in 2019.

CONCLUSIONS

There is a need to rigorously assess volunteer home visiting and whether it has a unique and important role on the service landscape, complementary to professional services. This research is the first trial of a volunteer home visiting program to be conducted in Australia and one of the largest of its kind worldwide.

CLINICALTRIAL

Australian New Zealand Clinical Trial Registry ACTRN12616000396426; https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=370304 (Archived by WebCite athttp://www.webcitation.org/70q42fU7V)

REGISTERED REPORT IDENTIFIER

RR1-10.2196/1000
Methodological Shortcomings of Wrist-Worn Heart Rate Monitors Validations (Preprint)
Authors: Sartor Francesco , Papini Gabriele , Cox Lieke Gertruda Elisabeth , Cleland John
Published: February 2018

UNSTRUCTURED

Wearable sensor technology could have an important role for clinical research and in delivering health care. Accordingly, such technology should undergo rigorous evaluation prior to market launch, and its performance should be supported by evidence-based marketing claims. Many studies have been published attempting to validate wrist-worn photoplethysmography (PPG)-based heart rate monitoring devices, but their contrasting results question the utility of this technology. The reason why many validations did not provide conclusive evidence of the validity of wrist-worn PPG-based heart rate monitoring devices is mostly methodological. The validation strategy should consider the nature of data provided by both the investigational and reference devices. There should be uniformity in the statistical approach to the analyses employed in these validation studies. The investigators should test the technology in the population of interest and in a setting appropriate for intended use. Device industries and the scientific community require robust standards for the validation of new wearable sensor technology.
The Generalizability of Randomized Controlled Trials of Self-Guided Internet-Based Cognitive Behavioral Therapy for Depressive Symptoms: Systematic Review and Meta-Regression Analysis (Preprint)
Authors: Lorenzo-Luaces Lorenzo , Johns Emily , Keefe John R
Published: February 2018

BACKGROUND

Self-guided internet-based cognitive behavioral therapies (iCBTs) for depressive symptoms may substantially increase accessibility to mental health treatment. Despite this, questions remain as to the generalizability of the research on self-guided iCBT.

OBJECTIVE

We sought to describe the clinical entry criteria used in studies of self-guided iCBT, explore the criteria’s effects on study outcomes, and compare the frequency of use of these criteria with their use in studies of face-to-face psychotherapy and antidepressant medications. We hypothesized that self-guided iCBT studies would use more stringent criteria that would bias the sample toward those with a less complex clinical profile, thus inflating treatment outcomes.

METHODS

We updated a recently published meta-analysis by conducting a systematic literature search in PubMed, MEDLINE, PsycINFO, and EMBASE. We conducted a meta-regression analysis to test the effect of the different commonly used psychiatric entry criteria on the treatment-control differences. We also compared the frequency with which exclusion criteria were used in the self-guided iCBT studies versus studies of face-to-face psychotherapy and antidepressants from a recently published review.

RESULTS

Our search yielded 5 additional studies, which we added to the 16 studies identified by Karyotaki and colleagues in 2017. Few self-guided iCBT studies excluded patients with severe depressive symptoms (6/21, 29%), but self-guided iCBT studies were more likely than antidepressant (14/170, 8.2%) studies to use this criterion. However, self-guided iCBT studies did not use this criterion more frequently than face-to-face psychotherapy studies (6/16, 38%). Beyond this, we found no evidence that self-guided iCBTs used more stringent entry criteria. Strong evidence suggested that they were actually less likely to use most entry criteria, especially exclusions on the basis of substance use or personality pathology. None of the entry criteria used had an effect on outcomes.

CONCLUSIONS

A conservative interpretation of our findings is that the patient population sampled in the literature on self-guided iCBT is relatively comparable with that of studies of antidepressants or face-to-face psychotherapy. Alternatively, studies of unguided cognitive behavioral therapy may sample from a more heterogeneous and representative patient population. Until evidence emerges to suggest otherwise, the patient population sampled in self-guided iCBT studies cannot be considered as less complex than the patient population from face-to-face psychotherapy or antidepressant studies.
Gelatin extraction from the indigenous Pangasius catfish bone using pineapple liquid waste
Authors: Atma Yoni , Ramdhani Hisworo
Published: February 2018

Gelatin extraction from fish bone has traditionally involved hydrogen chloride and/or sodium hydroxide during pre-treatment. However, these chemicals have begun to be abandoned because of their associated safety and environmental issues. Several studies have looked at the use of citric acid as a safer alternative in fish bone gelatin extraction. The aim of this research was to extract gelatin from the bone of Pangasius catfish with pineapple liquid waste. The extraction was performed in two steps: pre-treatment followed by main extraction at various times (24–56 h) and temperatures (45–75°C). Sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) was used as a confirmation test and showed a band for gelatin at ~120 kDa. Gelatin yields were calculated as the ratio of weight of dried gelatin to the total weight of fish ossein. The results indicated that pineapple liquid waste can be used for fish bone gelatin extraction. The recommended conditions for extraction of fish bone gelatin using pineapple liquid waste are 56 h of pre-treatment and 5 h of main extraction at a temperature of 75°C. The gelatin yield was 6.12% and the protein concentration 4.00 g/100 g.
Production Shifts and Upgrading in ASEAN Automotive Production Network: Case on Toyota-led Regional Value Chains
Authors: Arfani Riza Noer , Dewanta Awan Setya
Published: February 2018

The study aims at exploring the phenomenon of regional production network in ASEAN (Association of Southeast Asian Nations) automotive sector/industry by employing a firm as well as macro-level analysis of data gathered through combining techniques between desk-study and a series of fieldwork. It examines patterns of production and manufacturing activities of leading Japanese automotive firms and their upgrading strategies as showcased by Toyota in an endeavor to cast the much-aspired ASEAN regional value chains (RVCs). Production shifts have been apparent as indicated in the trade patterns and trends in value added of key automotive products traded between Japan and its ASEAN partners during the past 25 years. The shifts have resulted in deepened localization of production and manufacturing activities of Japanese automotive lead firms in ASEAN countries. Such dynamic shifts, as shown especially in passenger cars and automotive parts and accessories, have further prompted upgrading efforts by the lead firms (along with their suppliers, subsidiaries, and local partners) which suggest the functioning RVCs. The upgrading embraces areas of upstream (on research, development, and design or RD&D), midstream (on production, manufacturing, and assembly) as well as downstream (on sales, marketing, and after-market) activities. Future policy outlook lays on the ability of firms and other related stakeholders in the region’s automotive sector/industry to team up in the upgrading activities and hence capture the value-added. ASEAN-Japan long and strong historical relations facilitate the enhanced collaborative automotive industrial development, particularly in the areas of technical capacity formation and supporting industries.
THE ANALYSIS OF FACTORS AFFECT INCOME SMOOTHING ON MISCELLANEOUS INDUSTRY COMPANIES LISTED ON INDONESIA STOCK EXCHANGE
Authors: Anwar Arfianti Novita , Chandra Teddy
Published: February 2018

The objective of this research is to identify the factors which have influence on income smoothing at Miscellaneous Industry companies listed on Indonesian Stock Exchange period 2009-2013. Independent variables of this research include Return on Asset (ROA), Company Size, Dividend Payout Ratio (DPR), Debt to Equity Ratio (DER), and Financial Leverage while the dependent variable is income smoothing. The sample used in this study is 29 Miscellaneous Industry companies listed on the Indonesian Stock Exchange within a period of five years beginning in 2009 until 2013 with the selection method of purposive sampling. To identify the companies doing income smoothing, the Eckel Index was used. Statistical analysis used in this study uses descriptive statistics, multiple linear regressions and discriminant analysis. The results show that partially only company size and dividend payout ratio have significant impact on income smoothing meanwhile Return on Assets, Debt to Equity Ratio, Financial leverage did not show significant influence on income smoothing practices. The result of discriminant analysis shows there is significant difference of Return On Assets between income smoothing and non-smoothing company. 

Penelitian ini ditujukan untuk mengidentifikasi faktor-faktor yang mempengaruhi perataan laba pada perusahaan aneka industri yang terdaftar di Bursa Efek Indonesia pada periode 2009 – 2013. Variabel bebas yang digunakan dalam penelitian ini mencakup Return on Asset (ROA), Ukuran Perusahaan, Dividend Payout Ratio (DPR), Debt to Equity Ratio (DER) dan Financial Leverage, dengan variabel terikat perataan laba. Perusahaan yang menjadi sampel penelitian terdiri dari 29 perusahaan aneka industri yang dipilih dengan menggunakan metode purposive sampling. Untuk mengidentifikasi perusahaan-perusahaan yang melakukan praktik perataan laba dipergunakan indeks Eckel. Alat analisis yang dipergunakan untuk melakukan analisis deskriptif kuantitatif adalah analisis linear berganda dan analisis diskriminan. Hasil penelitian menunjukkan bahwa seluruh variabel bebas yang dipergunakan mampu menjelaskan proses perataan laba yang dilakukan oleh perusahaan dan yang memiliki pengaruh signifikan adalah ukuran perusahaan dan Dividend Payout Ratio. Sementara hasil dari analisis diksriminan menunjukkan bahwa terdapat perbedaan Return on Asset antara perusahaan yang melakukan praktik perataan laba dengan perusahaan yang tidak melakukan perataanlaba
PENGEMBANGAN MULTIMEDIA INTERAKTIF MENGGUNAKAN MICROSOFT POWER POINT DALAM PEMBELAJARAN MATEMATIKA KELAS X MA KM MUHAMMADIYAH PADANG PANJANG
Authors: Yusri Radhya , Husaini Al
Published: February 2018

Pemamfaatan media pembelajaran di MA KM Muhammadiyah Padangpanjang belum optimal, salah satu usaha yang dapat dilakukan untuk mengoptimalkan fasilitas yang ada adalah dengan mengembangkan suatu media pembelajaran berupa multimedia interaktif menggunakan Microsoft Power Point yang dikemas dalam CD (Compact Disc). Model pengembangan  menggunakan  model pengembangan 4-D yaitu define, design, develop dan disseminate. Hasil pengembangan menunjukkan bahwa media pembelajaran dengan multimedia interaktif menggunakan Microsoft Power Point dalam pembelajaran matematika kelas X MA KM Muhammadiyah Padangpanjang memenuhi kriteria media yang baik. Pada aspek kevalidan, kualitas isi dan tujuan pembelajaran media pembelajaran yang telah dibuat memperoleh penilaian 82 % dengan kategori sangat valid sedangkan dari sisi media itu sendiri memperoleh penilaian 82 % dengan kategori sangat valid. Sedangkan pada aspek kepraktisan media pembelajaran ini memperoleh penilaian 78 % dengan kategori praktis.
RANCANG BANGUN SISTEM E-RECRUITMENT BERBASIS ANDROID
Authors: Syastra Muhammad Taufik
Published: February 2018

Rancang bangun sistem e-recruitment ini bertujuan untuk mengakomodir kebutuhan perusahaan yang berkaitan dengan proses rekrutmen karyawan. Pada penelitian ini mengambil studi pada PT Mega Petro Synergy (PT MPS). PT. MPS merupakan perusahaan yang bergerak dibidang penyedia rekayasa konstruksi dan tenaga kerja industri berat. Kebutuhan PT MPS saat ini berkaitan dengan minimalisir biaya iklan, data yang real time dan juga kesalahan akibat proses penginputan data pelamar. Perancangan diarahkan pada pengembangan aplikasi berbasis android yang terintegrasi pada Man Power Information System (MPIS). Model SDLC yang digunakan adalah Waterfall. Perancangan aplikasi ini menggunakan pemodelan Unified Modelling Languange (UML) meliputi use case diagram, class diagram, activity diagram, dan sequence diagram. Selain UML, teknologi yang digunakan dalam proses perancangan adalah javascript, PHP, AngularJS, Laravel dan MySql. Penelitian ini menghasilkan aplikasi berbasis android yang dapat gunakan sebagai media iklan, penyedia data real time, serta mempermudah proses penginputan data pelamar.