bluuebunny/crossref_metadata_2025 huggingface dataset:
ANALISIS TINDAK TUTUR DALAM FILM YANG TAK TERGANTIKAN KARYA HERWIN NOVIANTO
Authors: Samrina Titi , Nazriani Nazriani , Nurlaila Maryam
Published: June 2023

Tujuan penelitian ini adalah untuk mengetahui dan mendeskripsikan bentuk tindak tutur yang terdapat dalam film Yang Tak Tergantikan Karya Herwin Novianto. Penelitian ini menggunakan metode kualitatif yang bersifat deskriptif. Jenis penelitian yaitu kepustakaan. Sumber data dalam penelitian ini yaitu film Yang Tak Tergantikan. Teknik pengumpulan data dalam penelitian ini adalah teknik simak dan teknik catat. Hasil penelitian menunjukan bahwa penulis dapat memberikan kesimpulan dalam Film Yang Tak Tergantikan karya Herwin Novianto terdapat tiga macam jenis tindak tutur yaitu tindak tutur lokusi, ilokusi dan perlokusi. Tindak tutur lokusi yang terdata pada analisis ini berjumlah 3 data yang terbagi dalam bentuk tindak tutur deklaratif, imperatif dan interogratif. Tindak tutur ilokusi yang terdata pada analisis data berjumlah 14 data yang terbagi dalam 4 bentuk ilokusi yaitu ilokusi asertif sebanyak 3 data, ilokusi direktif sebanyak 3 data, ilokusi komitif sebanyak 3 data dan ilokusi ekspresif sebanyak 5 data. Tindak tutur perlokusi terdata berjumlah 3 data terbagi dalam bentuk tindak tutur perlokusi verbal 1 data, perlokusi non verbal 1 data dan perlokusi verbal non verbal 1 data.
La edición del Quijote en Argentina (1900-1983)
Authors:   , Calabrese Martín Ezequiel
Published: June 2023

El objetivo central de este trabajo es analizar en profundidad la totalidad de las ediciones locales de la obra cervantina, publicadas entre 1900 y 1983, abordando tanto los aspectos materiales de las mismas como su impacto en el contexto de edición. La delimitación temporal planteada está sujeta a las siguientes consideraciones. La fecha de 1900 se corresponde con la primera impresión de la empresa internacional Casa Maucci. Hemos decidido delimitar cronológicamente nuestro análisis en el año 1983, considerando la primera edición posterior a la última dictadura militar. La historia editorial latinoamericana se empareja con la historia editorial del Quijote. En la investigación se establecen puntos de contacto entre el desarrollo del ámbito editorial local y la historia editorial local de la obra cervantina, dado que los diversos adelantos tecnológicos llevados adelante por las empresas editoriales repercuten en los modos de publicar la obra y en el alcance (local e internacional) de la misma. El aporte de McKenzie en su obra Bibliografía y Sociología de los Textos (2005) ha permitido abordar el corpus de más de 60 ediciones analizadas, teniendo en cuenta diversos estudios sobre la Historia del Libro y de la Edición en habla hispana. A partir de Robert Darnton (2014) y su esquema del “Circuito de la Comunicación” que se conforma alrededor del objeto libro, se identifican una serie de agentes que participan en la publicación de una obra, a fin de poder analizarlos de manera concreta en el abordaje de cada edición del Quijote. Tomando como base la disciplina esbozada por Donald McKenzie, la Bibliografía y Sociología de los textos, se proponen en este apartado los lineamientos teóricos necesarios para poder analizar, de manera fundamentada, cada una de las ediciones locales de la obra como una propuesta de lectura. La obra delimita el objeto de análisis en tres grandes arcos temporales, que siguen los estudios precedentes del campo editorial realizados por De Diego (2016), dentro de los cuales se analiza detalladamente cada edición: - Primer arco temporal (1900-1919): las primeras ediciones conmemorativas y la organización del campo editorial; - Segundo arco temporal (1938-1955): la época de oro del campo editorial argentino; - Tercer arco temporal (1956-1983): la consolidación del mercado interno.
Dynamics of medium-deep seismicity parameters before large earthquakes in South Asian seismic focal zones
Authors: Mikheeva A.V.
Published: June 2023

The study was continued to reveal the spatio-temporal relationship between strong crustal shocks and the moderate, medium-deep seismicity that precedes them. In the area of preparation of these shocks, the following regularities were revealed: in space – the presence of a high creepex gradient (in particular, the boundary transition between its positive and negative anomalies), in time – a direct correlation of the graphs MS(t) and Cr(t), indicating the creation in the period of preparation of the source under the conditions of a strictly determined influence of the source-size on creepex. Since the proportional dependence of the creepex on the geometric size of the source is usually associated with an increased heterogeneity of the medium in the source, it can be assumed that the processes of brittle fracture of blocks of the undercutting crust coexist here with the processes of inflow of deep mantle material, which ensures the heterogeneity of the properties of the medium in the area of preparation of large earthquakes in the South Asian subduction zones. This conclusion is confirmed on the average creepex anomaly maps by the presence of their increased gradient in the deep region of the preparation of these events.
What Makes Problem-Solving Practice Effective? Comparing Paper and AI Tutoring
Authors: Borchers Conrad , Carvalho Paulo F. , Xia Meng , Liu Pinyang , Koedinger Kenneth R. , Aleven Vincent
Published: June 2023

In numerous studies, intelligent tutoring systems (ITSs) have proven effective in helping students learn mathematics. Prior work posits that their effectiveness derives from efficiently providing eventually-correct practice opportunities. Yet, there is little empirical evidence on how learning processes with ITSs compare to other forms of instruction. The current study compares problem-solving with an ITS versus solving the same problems on paper. We analyze the learning process and pre-post gain data from N = 97 middle school students practicing linear graphs in three curricular units. We find that (i) working with the ITS, students had more than twice the number of eventually-correct practice opportunities than when working on paper and (ii) omission errors on paper were associated with lower learning gains. Yet, contrary to our hypothesis, tutor practice did not yield greater learning gains, with tutor and paper comparing differently across curricular units. These findings align with tutoring allowing students to grapple with challenging steps through tutor assistance but not with eventually-correct opportunities driving learning gains. Gaming-the-system, lack of transfer to an unfamiliar test format, potentially ineffective tutor design, and learning affordances of paper can help explain this gap. This study provides first-of-its-kind quantitative evidence that ITSs yield more learning opportunities than equivalent paper-and-pencil practice and reveals that the relation between opportunities and learning gains emerges only when the instruction is effective.
Effect of Dalugha (Cyrtosperma merkusii) Debris Supplementation on Hemoglobin, Cholesterol and Blood Glucose Levels in Broiler Chickens
Authors: Rayer Debby J.J. , Moko Emma Mauren , Rahardiyan Dino , Tengker Anita C.C , Rompas Christny F. , Rawung Livana Dethris
Published: June 2023

Feed is an important factor that influences the chicken's development and growth. Meanwhile, dalugha debris is a by-product of dalugha processing which is expected to be a source of feed for the growth and development of broiler chickens. The good feed can optimize metabolic processes in the animal so that it can support the process of growth and development of the animal. This study aims to determine the levels of hemoglobin, cholesterol, and blood glucose in broiler chicken that is given dalugha debris supplementation. This study used a completely randomized design (CRD), where as many as 60 docs of unsex chicken used were divided into four treatments and three replications. Each replication consisted of five chickens. The treatment given was the concentration of dalugha debris at several doses: 0%, 0.065%, 0.13%, and 0.26%. The parameters observed were hemoglobin, cholesterol, and blood glucose levels. The results showed that the provision of dalugha debris in the feed significantly (p<0.05) affected the blood glucose level, but did not affect the cholesterol and hemoglobin levels (p>0.05) of the broiler chicken.
Keywords: Broiler chicken; blood biochemistry; Cyrtosperma merkusii
Pengaruh Suplementasi Debris Dalugha (Cyrtosperma merkusii) Terhadap Kadar Hemoglobin, Kolesterol dan Glukosa Darah Ayam Broiler
ABSTRAK
Pakan merupakan faktor penting yang mempengaruhi pertumbuhan dan perkembangan ayam. Debris dalugha adalah hasil samping pengolahan tepung dalugha yang sudah tidak digunakan lagi dan diperkirakan dapat menjadi sumber pakan untuk pertumbuhan dan perkembangan ayam daging. Pakan yang baik dapat mengoptimalkan proses metabolisme pada hewan sehingga akan mendukung proses pertumbuhan dan perkembangan hewan tersebut. Penelitian ini bertujuan untuk mengetahui kadar hemoglobin, kolesterol, dan glukosa darah pada ayam yang disuplementasikan debris dalugha dalam pakan.  Penelitian ini menggunakan rancangan acak lengkap (RAL), di mana sebanyak 60 ekor ayam dikelompokkan ke dalam empat perlakuan dengan tiga ulangan. Perlakuan suplementasi debris dalugha diberikan pada beberapa dosis yaitu; 0%, 0.065%, 0.13% and 0.26%.  Parameter yang diamati berupa kadar hemoglobin, kolesterol dan glukosa darah. Hasil penelitian menunjukkan bahwa pakan yang ditambahkan suplementasi debris dalugha secara signifikan (p<0.05) mempengaruhi kadar glukosa darah, tetapi tidak mempengaruhi (p>0.05) kadar hemoglobin dan kolesterol darah ayam daging. Hal ini menunjukkan bahwa debris dalugha memiliki potensi sebagai bahan penyususn pakan ayam broiler.
Kata kunci: Ayam daging; biokimia darah; Cyrtosperma merkusii
The Intelligibility of Korean-Accented English in the Lingua Franca Context
Authors:   The English Teathers Association in Korea, Chung Bohyon , Bong Hyun Kyung Miki
Published: June 2023

This study aimed to establish an empirical basis for prioritizing English as a Lingua Franca (ELF) instruction by evaluating the importance of “intelligibility” in communication with accented English speakers. It specifically examined the claims surrounding the Lingua Franca Core (LFC) features as the minimum requirements for intelligibility in ELF contexts. The experiment focused on the intelligibility of Korean-accented English (KoE) and general American English (AmE) to Korean-Speaking Learners (KSLs) and Japanese- Speaking Learners (JSLs). The findings indicated that AmE was more intelligible to both non-native English speaker groups. In contrast, KoE’s intelligibility was hindered by non- LFC features such as the pronunciation of the dark /l/ sound and specific vowel qualities. These results challenge the LFC proposal and suggest the need for a modified set of LFC features in ELF teaching and learning. The implications of this study are significant for English language education, highlighting the necessity of considering different accents and non-LFC features in ELF communication. By incorporating these aspects into instruction, teachers can better prepare learners for real-world interactions in diverse linguistic contexts. This approach enhances learners’ confidence and proficiency in understanding and being understood by individuals from various linguistic backgrounds, fostering successful intercultural exchanges.
An analysis of the inter-grade continuity of the reading passages of high school English mock CSAT tests using Coh-Metrix
Authors:   The English Teathers Association in Korea, Ryu Jisu , Jeon Moongee
Published: June 2023

The main objective of this study was to analyze the continuity of reading passages in high school English mock College Scholastic Ability Test (CAST) exams using Coh-Metrix, a multi-level text analysis tool. To achieve this, the study constructed a corpus of reading passages from the 2022 high school English mock exams and subjected them to a broad range of Coh-Metrix measures. These measures included basic measures (the number of words, the number of sentences, average word length, average sentence length), word frequencies (word frequencies for content words), word features (imageability, concreteness, age of acquisition, familiarity), lexical diversity measures (type-token ratios for content words), personal pronouns (first person pronouns, second person pronouns, third person pronouns), connectives, readability indices (Flesch Reading Ease, Flesch-Kincaid Grade Level), syntactic complexity (noun density scores, the number of words before main verbs), coreference cohesion measures, and semantic cohesion measures. The main results revealed that the continuity of high school English mock tests was well established for average word and sentence length measures, the average number of words, word frequencies, word familiarity, second person pronouns, standard readability indices, and syntactic complexity measures. These findings have implications for the development of reading passages in high school English mock exams.
Analisis Komunikasi Publik Dalam Mewujudkan Kesejahteraan Masyarakat
Authors: Mukoyimah Mukoyimah , Bariyah Choerul
Published: June 2023

Public communication is one of the efforts to provide information to the public in order to minimize public miscommunication. This study aims to find out how public communication is carried out by the government and investors, in this case, BPI (Bhimasena Power Indonesia) regarding the scope of the PLTU in the Batang region. The scope of PLTU development concerns how the raw materials are used and the safety and welfare of the surrounding community. Research using field research method with a descriptive approach. The main source of information is the results of interviews. While the data analysis technique that the author uses is data reduction then presenting the data and the last is concluding. The results of the author's research show that investors' efforts to socialize the establishment of PLTU are not easy. There are many objections from the community, both fighting for environmental health and land acquisition by the PLTU. The government and investors are trying to educate the public. Coal fuel is not without impact, but this impact can be minimized by having a good living culture and good management of coal waste by BPI. The efforts of the government and BPI in educating the public are carried out using an individual approach (presence at community forums) and also through the media, by providing information, complaints, and education services (in the form of comics). This aims to make it easier for the public to understand the intent and purpose of the establishment of the PLTU.
Seizing Public Digital Dominance; The Phenomenon Of Mainstream Islamic Media Digital Battle
Authors: Hamidah Kamilia
Published: June 2023

The authority of digital public discourse indirectly impacts one's religious point of view, the phenomenon of digital religion has caused mainstream Islamic websites to strive for the dominance of the public digital mass. This paper will examine the phenomenon of competition among mainstream Islamic websites and mainstream non-affiliated websites in seizing public digital dominance. Data Reportal on Digital Indonesia 2023 put Indonesia as the largest internet users in the world, with a population of around 277,7 million with a total active internet user of 212,9 million, internet penetration stood at 77,0 percent. Indonesia also home to 167,0 million social media users equating to 60,4 percent of the total population. Total of 352,8 million cellular mobile connections were active in Indonesia, this figure equivalent to 128,0 percent of the total population. The paper elaborates the prevalent competition between Islamic media using a phenomenological approach based on digital data and a variety of digital analysis tools. This study demonstrates how the intensity of contestation persists and has subsequently created digital communities with divergent religious viewpoints that have subconsciously created social segmentation that strengthens group exclusivism.
Analisis Konten Film “Mak Cepluk” Sebagai Pelestarian Permainan Tradisional Indonesia
Authors: Kurniawan Fajar Adhi , Safitri Tsania Firda Ayu
Published: June 2023

Children's interest in using modern games is very strong, making children less interested in traditional games. The way that can be done to preserve traditional games is to socialize traditional games. One of the effective socialization today is to disseminate it using communication media, namely films. The method used in this research is to use qualitative research methods. The results showed that the content of the movie "Mak Cepluk" contains cultural preservation content, especially in the game of pletokan. The two elements that make up the movie are narrative and cinematic elements, the narrative elements in the movie "Mak Cepluk" contain a coherent story and contain elements of traditional games clearly. From the cinematic elements, the efforts to preserve the traditional game of pletokan are well depicted from shooting techniques, composition, editing techniques, and movie continuity.
DForest: A Minimal Dimensionality-Aware Indexing for High-Dimensional Exact Similarity Search
Authors: Li Lingli , Sun Wenjing , Wu Baohua
Published: June 2023

The problem of similarity search in high-dimensional space is a fundamental problem with numerous applications in computer science, but remains challenging due to the curse of dimensionality. To address this challenge, in this paper, DForest, a novel indexing approach, is proposed for both range and kNN queries on high-dimensional data. Unlike the previous similarity search approaches, which perform a dimensionality reduction on all objects by the same fixed value, we discover the minimal dimensionality each object requires to be under a loss threshold and attempt to reduce the dimensionality for each object individually. Furthermore, the query performance is also optimized by deriving the upper and lower bounds of retrieved blocks and calculating distances in a low-embedding space preferentially. Theoretical analysis is provided to support our search strategy. Extensive experiments demonstrate that DForest significantly outperforms all the state-of-the-art competitors in terms of query time, and exhibits good scalability.
Gated Cross-Attention for Universal Speaker Extraction: Pay attention to the Speaker’s Presence
Authors: Zhang Yiru , Li Zeke , Liu Bijing , Fan Haiwei , Yang Yong , Yang Qun
Published: June 2023

Current speaker extraction models have achieved good performance in extracting target speech from highly overlapped multi-talker speech. But in real-world applications, the multi-talker speech is sparsely overlapped and the target speaker may be absent from the speech mixture, making it difficult for the model to extract desired speech in this situation. The universal speaker extraction is proposed to solve the problem by evaluating the quality of estimated speech signals and silence. However, the design of existing universal speaker extraction models does not take into account distinguishing the presence or absence of the target speaker. In this paper, we propose a gated cross-attention network for universal speaker extraction. In our model, the cross-attention mechanism learns the correlation between the target speaker and the speech to distinguish whether the target speaker presents or not. According to the correlation, the gate mechanism makes the model focus on extracting speech when the target is present, while filtering out the features when the target is absent. Meanwhile, we propose a joint loss function to optimize the network in both target present and absent scenarios. We conducted experiments on the LibriMix dataset with various scenarios and evaluated the performance in terms of speech quality and speaker extraction error rate. The experiment results show that our proposed method outperforms the baselines in all of the scenarios.
Lightweight Learning From Label Proportions On Satellite Imagery
Authors: Ramos-Pollan Raul , Gonzalez Fabio A.
Published: June 2023

This work addresses the challenge of producing chip level predictions on satellite imagery when only label proportions at a coarser spatial geometry are available, typically from statistical or aggregated data from administrative divisions (such as municipalities or communes). This kind of tabular data is usually widely available in many regions of the world and application areas and, thus, its exploitation may contribute to leverage the endemic scarcity of fine grained labelled data in Earth Observation (EO). This can be framed as a Learning from Label Proportions (LLP) problem setup. LLP applied to EO data is still an emerging field and performing comparative studies in applied scenarios remains a challenge due to the lack of standardized datasets. In this work, first, we show how simple deep learning and probabilistic methods generally perform better than standard more complex ones, providing a surprising level of finer grained spatial detail when trained with much coarser label proportions. Second, we provide a set of benchmarking datasets enabling comparative LLP applied to EO, providing both fine grained labels and aggregated data according to existing administrative divisions. Finally, we argue how this approach might be valuable when considering on-orbit inference and training. Source code is available at https://github.com/rramosp/llpeo.

[+] This work has been submitted to the IEEE for review and possible publication. Copyright might be transferred without notice, after which this version may no longer be accessible.
Safe Iterative Feedback Linearization Control Design for Collaborative Robots
Authors: Arab Aliasghar
Published: June 2023

Abstract— Intelligent autonomous robotic systems are not limited to industrial applications and are being used for professional service and household domains. The vast amount of these robots are designed to work alongside humans in close proximity which pushes the need for safety-guaranteed control systems. Assuring the safety of humans and the environment while maintaining the performance of the robot is still a challenging problem. We proposed a safe iterative feedback linearization control method for the safe operation of collaborative robots. This proposed approach combines feedback linearization with intelligent predictive algorithms to achieve stable and safe control of the robot’s motion. By using real-time feedback and monitoring user interactions, I demonstrate how to improve performance over time while maintaining safety. Our proposed method shows how to safely improve performance in collaborative robotics applications. Experimental results show our designed control system is a promising approach for achieving safe and efficient control of collaborative robots.
Bihar Tourism Management System
Authors: Pandey Vishal , kumar Ankesh , Sinha Ashish Kumar
Published: June 2023

The Bihar Tourism Management System (BTMS) is an online tool that was created to administer and promote tourism in the Indian state of Bihar. The system's goal is to make it easy for travelers to find information about travel options, accommodations, and other relevant businesses.Visitors to the BTMS portal can use it to plan and book their travel online. The system's user-friendly interface allows tourists to plan and book their vacations to a variety of tourist destinations in Bihar.The purpose of this document is to discuss ways to improve tourists' overall experiences and further promote tourism within the state. As information becomes more readily available, systems should offer helpful information about popular tourist spots in Bihar, including any cultural relevance.The system can be designed with the help of artificial intelligence to support multiple languages to cater to the needs of tourists who do not speak English or Hindi. The system can also have a feedback mechanism where tourists can rate their experience and provide feedback on how the system can be improved. This feedback can help to identify areas of improvement and make necessary changes. Additionally, marketing efforts should be improved to attract more tourists to Bihar.
Pengembangan Media OPER (Organ Pernapasan) Untuk Meningkatkan Motivasi Siswa Kelas V Sekolah Dasar
Authors: Widhi Resti Nugrahaning , Hidayat Otib Satibi , Hasanah Uswatun
Published: June 2023

Penelitian ini bertujuan untuk mengetahui dan menganalisis kebutuhan media pembelajaran pada materi Organ Pernapasan Manusia dan Hewan menggunakan media permaianan ular tangga untuk meningkatkan motivasi belajar siswa kelas V sekolah dasar. Jenis penelitian ini adalah Research and Development (R&D) dan hanya terfokus pada teknik analysis yang menjadi dasar untuk melakukan sebuah penelitian. Teknik pengumpulan data menggunakan non tes yaitu observasi yaitu dengan melakukan pengamatan secara langsung serta sebuah angket yang disebar dan ditujukan dijawab oleh guru wali kelas V serta siswa kelas V. Penelitian ini dilaksanakan pada tanggal 04 April 2023 di SDI Nurul Yaqin, Kelurahan Cipinang Besar Utara, Kecamatan Jatinegara, Jakarta Timur, dengan sampel 18 siswa serta 1 guru wali kelas V. Berdasarkan hasil analisis kebutuhan diperoleh hasil bahwa siswa merasa bosan dengan teknik mengajar guru yang masih menggunakan metode literasi dan ceramah, selanjutnya sekolah tersebut membutuhkan suatu media pembelajaran dalam pembelajaran IPA materi organ pernapasan manusia dan hewan untuk menunjang proses belajar agar anak didik termotivasi dan giat dalam proses pembelajaran.
IDENTIFIKASI PEMBENTUKAN KO-KRISTAL TRIKLABENDAZOL-ASAM OKSALAT DAN UJI KELARUTANNYA
Authors: Fikri Alatas , Sutarna Titta Hartyana , Asilla Alya Nur , Pratiwi Sintia Resni
Published: June 2023

Triklabendazol (TBZ) adalah suatu turunan benzimidazol yang direkomendasikan pada pengobatan fascioliasis dan memiliki kelarutan rendah di dalam air. Perbaikan sifat fisikokimia obat, termasuk kelarutan bisa dilakukan dengan cara mengubah bentuk padatannya menjadi ko-kristal. Penelitian ini bertujuan untuk mengidentifikasi pembentukan ko-kristal antara TBZ dengan asam oksalat (OXA) dan menguji kelarutannya di dalam air. Identifikasi awal terbentuknya ko-kristal TBZ-OXA dilakukan dengan membangun kurva kelarutan fasa TBZ di dalam larutan OXA (0,2-2M) dan mengamati perubahan morfologi kristal setelah campuran TBZ-OXA direkristalisasi di dalam metanol. Selanjutnya dilakukan penggilingan campuran ekimolar TBZ-OXA dengan penambahan beberapa tetes metanol. Untuk memastikan pembentukan ko-kristal, hasil penggilingan dikarakterisasi dengan difraktometer sinar-X serbuk. Prediksi rasio molar ko-kristal TBZ-OXA yang terbentuk dilakukan dengan menggunakan metode differential scanning calorimetry (DSC).  Kurva kelarutan fasa TBZ-OXA mengikuti jenis Bs, sementara habit kristal campuran ekimolar TBZ-OXA berbeda dengan habit kristal TBZ dan OXA murni setelah direkristalisasi dalam metanol. Hasil-hasil identifikasi awal ini mengindikasikan adanya interaksi antara TBZ dan OXA untuk membentuk ko-kristal. Pola difraksi sinar-X serbuk hasil penggilingan TBZ-OXA memperlihatkan adanya puncak-puncak baru yang tidak muncul pada TBZ dan OXA murni dan hilangnya puncak-puncak khas dari kedua komponen awalnya yang menegaskan terbentuknya ko-kristal TBZ-OXA. Berdasarkan termogram DSC diduga antara TBZ dan OXA membentuk ko-kristal dengan rasio molar 2:1 dengan titik lebur di 111,98°C. Ko-kristal TBZ-OXA memiliki kelarutan di dalam air 6,4 kali lipat daripada TBZ murni. Hasil-hasil penelitian ini telah mengidentifikasi pembentukan ko-kristal antara triklabendazol dan asam oksalat yang memiliki kelarutan lebih tinggi daripada triklabendazol murni.
AKTIVITAS ANTIOKSIDAN DAN INHIBISI ENZIM TIROSINASE EKSTRAK ETANOL BUAH GANDARIA (Bouea macrophylla Griff.) SECARA IN VITRO
Authors: Dhyneu Dwi Jayantie , Yunahara Farida , Shelly Taurhesia
Published: June 2023

Radikal bebas merupakan penyebab masalah kulit, salah satunya adalah hiperpigmentasi yaitu disebabkan oleh adanya peningkatan aktivitas enzim tirosinase. Ekstrak etanol 70% buah gandaria (Bouea macrophylla Griff.) memiliki senyawa fenolik, tanin, vitamin C, flavonoid, flavonol, serta antosianin yg bisa menangkal radikal bebas serta mengurangi risiko permasalahan kulit. Tujuan penelitian ini untuk mengetahui aktivitas antioksidan serta inhibisi enzim tirosinase ekstrak etanol buah B. macrophylla secara in vitro. Pada pembuatan ekstrak buah B. macrophylla, pelarut yang digunakan nya adalah etanol 70% dengan metode maserasi, skrining fitokimia, uji aktivitas antioksidan menggunakan metode DPPH, serta inhibisi enzim tirosinase memakai substrat L-DOPA. Aktivitas antioksidan ekstrak etanol buah B. macrophylla memiliki kategori sangat kuat dengan nilai IC50 47,064 µg/mL, serta inhibisi enzim tirosinase paling tinggi diperoleh dengan nilai 47,529%.
MOLECULAR DOCKING DAN UJI TOKSISITAS REMDESIVIR, LOPINAVIR, RITONAVIR DAN FAVIPIRAVIR TERHADAP M-PROTEASE SARS-CoV-2
Authors: Anna Yuliana , Oktaviani Ayu Saputri , Salsabila Adlina
Published: June 2023

Protease inhibitor Lopinavir, Ritonavir, Remdesivir yang bekerja pada RNA polimerase virus (Main Protease) diprediksi dapat memberikan aktivitas baik dalam pengikatan dengan reseptor secara in silico dan potensial sebagai penghambat COVID-19. Tujuan penelitian ini adalah untuk mengetahui toksisitas Remdesivir, Lopinavir, Ritonavir, dan Favipiravir dengan menggunakan software Toxtree dan mengetahui interaksi dan kestabilan obat Remdesivir, Lopinavir, Ritonavir, dan Favipiravir dengan resepetor M-Protease SARS-CoV-2 menggunakan metode Molecular Docking dan Molecular Dynamic. Senyawa obat uji dianalisis menggunakan lipinski rule's of five, uji toksisitas menggunakan program Toxtree, simulasi Molecular Docking menggunakan Autodock 1.5.6 dan simulasi Molecular Dynamic menggunakan MOE (Molecular Operating Environtment). Hasil Molecular Docking favipiravir dengan reseptor 5RF3 sebesar -6.32 kkal/mol, lopinavir dengan reseptor 5RL4 sebesar -17.86 kkal/mol, obat Ritonavir dengan reseptor 5RL5 sebesar -17.19 kkal/mol , dan obat Remdesivir dengan reseptor 5R83 sebesar -14.90 kkal/mol. Hasil Molecular Dynamic senyawa obat Favipiravir, Lopinavir, Remdesivir, dan Ritonavir dilihat dari hasil procheck ramachandran hasil persentase most favoured region 50% dan disallowed region 15% dan kecocokan hasil residu asam amino, uji toksisitas menggunakan Toxtree diperoleh kategori kelas III, tidak bersifat karsinogenik genotoksik dan non genotoksik. Senyawa obat uji memiliki interaksi yang kuat dan stabil sehingga dapat dijadikan sebagai kandidat yang berpotensi untuk pengobatan anti SARS-CoV-2.
HUBUNGAN TINGKAT PENGETAHUAN DAN PERILAKU PASIEN HIPERTENSI TERHADAP TATALAKSANA HIPERTENSI DI KLINIK DOKTER 24 JAM MELATI TASIKMALAYA
Authors: Kamiel Roesman Bachtiar , Eddy Suhardiana , Salsabila Adlina , Srie Rezeki Nur Endah , Ali Nofriyaldi , Ayu Rahmawati
Published: June 2023

Prevalensi penyakit hipertensi di kota Tasikmalaya masih tergolong tinggi. Salah satu penyebabnya adalah tingkat kesadaran penderita terhadap kesehatan masih rendah. Masih banyak pasien yang tidak menyadari dirinya menderita hipertensi dan tidak mematuhi pencegahan hipertensi. Hal tersebut terjadi karena kurangnya pengetahuan dan perilaku terhadap tatalaksana hipertensi. Tujuan penelitian ini adalah untuk mengetahui hubungan tingkat pengetahuan dan perilaku pasien hipertensi terhadap tatalaksana hipertensi di Klinik Dokter 24 Jam Melati Tasikmalaya. Desain penelitian menggunakan cross sectional study. Pengambilan sampel menggunakan accidental sampling berdasarkan kriteria inklusi sebanyak 100 responden. Variabel penelitan yaitu, tingkat pengetahuan hipertensi dan perilaku pasien terhadap tatalaksana hipertensi. Analisa data dengan analisis univariat (manual) dan analisis bivariat (uji chisquare) Hasil penelitian menunjukkan bahwa karakteristik responden penderita hipertensi di Klinik Dokter 24 Jam Melati Tasikmalaya, yaitu mayoritas responden berusia ≥ 50 tahun, pendidikan terakhir SD, berjenis kelamin perempuan, tingkatan hipertensi Stadium 1, obat yang digunakan amlodipin, dan tidak memiliki riwayat keluarga hipertensi. Pengetahuan pasien hipertensi terhadap tatalaksana hipertensi termasuk kategori baik dan perilaku pasien hipertensi terhadap tatalaksana hipertensi termasuk perilaku positif. Hal ini terlihat dari hasil uji bivariat terdapat hubungan yang signifikan tingkat pengetahuan pasien hipertensi dengan perilaku pasien hipertensi terhadap tatalaksana hipertensi nilai ρ = 0.000).
AKTIVITAS AFRODISIAK EKSTRAK ETANOL UMBI TUMBUHAN BUNGKUS (Smilax rotundifolia L.) TERHADAP FERTILITAS TIKUS PUTIH JANTAN
Authors: Ayu Wulandari , Kiki Rizki Handayani , Monica Sandra Makatang
Published: June 2023

Beberapa negara, termasuk Indonesia, khususnya di wilayah Papua, memakai tanaman bungkus (Smilax rotundifolia) sebagai penambah seksual, namun belum ada penelitian lebih lanjut mengenai pengaruh aksi afrodisiaknya terhadap fertilitas pada tikus putih jantan. Tujuan dari penelitian ini adalah untuk menentukan metabolit sekunder yang terdapat pada umbi tanaman Smilax rotundifolia, untuk menentukan efek afrodisiak ekstrak umbi tanaman Smilax rotundifolia terhadap parameter fertilitas tikus putih jantan (Rattus norvegicus). Penelitian ini memakai 45 tikus putih yang terbagi dengan rasio 1: 2 (tikus betina;tikus jantan) kedalam kelompok perlakuan kontrol normal, kontrol positif dan kelompok ekstrak dosis 200 mg/kgBB. Hasil penelitian dianalisis memakai uji statistik SPSS menunjukkan bahwa ekstrak akar tanaman bungkus mengandung metabolit sekunder flavonoid, saponin dan antioksidan kuat. Pemberian ekstrak umbi bungkus (Smilax rotundifolia L.) dengan dosis 200 mg/kgBB menunjukan perbedaan nilai persentase indeks kehamilan dan pengaruh yang signifikan pada nilai indeks fertilitas.
Ambientes de inclusión para el desarrollo del pensamiento numérico con población con síndrome de down
Authors: Escobar Buitrago Luisa Valeria , Torres Garzón Ingry Yuliana , Firigua Bejarano Juan David
Published: June 2023

La importancia de tratar sobre una educación inclusiva es hacer que la humanidad obtenga la aceptación hacia la diversidad, donde se encuentre un mundo lleno de posibilidades reconociendo todos los tipos de población entre ella las personas con Síndrome de Down, lo cual consiste en que la educación esté centrado en el respeto y la valoración de la diversidad, haciendo un enfoque general en las necesidades que esta población tiene, desarrollando habilidades para su desenvolvimiento tanto personal como laboral en determinada sociedad, por lo tanto el objetivo principal de este trabajo es desarrollar el pensamiento numérico de los estudiantes de los grados transición, primero y cuarto de la Institución Educativa Adolfo León Gómez, sede San Pedro, Pasca, incluyendo población con síndrome de Down a través de escuela nueva en la ruralidad.Para lograr el objetivo se trabajó un diseño metodológico con enfoque mixto, el cual se dividió en cuatro etapas, estas son: caracterizar la población y su entorno, identificando las barreras de inclusión que se presentan, luego crear una secuencia didáctica en base al DUA y el PIAR del estudiante con Síndrome de Down, aplicarla por sesiones y por último evidenciar el desarrollo numérico en los estudiantes, que se modificará por medio de la implementación de la secuencia didáctica, lo cual se puede demostrar a través de las pruebas de entrada y salida , y la documentación de los diarios de campo.luego crear una secuencia didáctica en base al DUA y el PIAR del estudiante con Síndrome de Down, aplicarla por sesiones y por última evidenciar el desarrollo numérico en los estudiantes, que se modificará por medio de la implementación de la secuencia didáctica, lo cual se puede demostrando a través de las pruebas de entrada y salida, y la documentación de los diarios de campo.luego crear una secuencia didáctica en base al DUA y el PIAR del estudiante con Síndrome de Down, aplicarla por sesiones y por última evidenciar el desarrollo numérico en los estudiantes, que se modificará por medio de la implementación de la secuencia didáctica, lo cual se puede demostrando a través de las pruebas de entrada y salida, y la documentación de los diarios de campo.
Arquétipo de governança para sistema de esgotamento sanitário adequado
Authors: Dusi Pereira Luciane , Bach Trevisan Alexandre , Heleno Sezerino Pablo
Published: June 2023

O Serviço de Esgotamento Sanitário (SES), para além da infraestrutura necessária, requer instituições capazes de garantir o fornecimento adequado dos serviços. Para tanto, o tema da governança vem ganhando notoriedade no sentido de ser capaz de trazer esse enfoque mais institucional e humano ao tema. Neste trabalho buscou-se desenvolver uma proposta de arquétipo para a governança do SES em quatro etapas: (i) a definição de governança utilizando o Decreto Federal 9.203/2017 e o Referencial para Avaliação de Governança em Políticas Públicas do Tribunal de Contas da União (TCU); (ii) a sistematização da Lei 11.445/2007 atualizada pela Lei 14.026/2020, visando identificar os mecanismos que regem a governança; (iii) a representação trina e multinível da governança; (iv) os atributos atrelados à governança. Trabalhar com a ideia de arquétipo para a governança do SES adequado simplifica a comunicação, tornando-a clara e compreensível aos atores interessados.
Palavras-chave: Governança. Serviço de Esgotamento Sanitário. Política Pública.
A redução da DBO na despoluição de córregos urbanos e sua percepção no cotidiano dos moradores: caso Curso d’água Tenente Rocha (2021)
Authors: Salgado Marcio , Negrão Mucci José Luiz
Published: June 2023

O Curso d’água Tenente Rocha, situado na Zona Norte da capital paulista, tem sido beneficiado pelo Programa Córrego Limpo (PCL) desde 2007, sendo considerado atualmente despoluído tanto pela Prefeitura de São Paulo como pela Sabesp. Entretanto, fatores locais associados à reincidência de cargas pontuais e difusas têm causado alterações significativas na qualidade de suas águas. Desenvolveu-se uma pesquisa exploratória de caráter qualitativo, com o objetivo de analisar a perspectiva dos moradores em relação à redução da Demanda Bioquímica de Oxigênio (DBO), efetivada no processo de despoluição do Córrego Tenente Rocha. Foi evidenciado que, após as ações iniciais do PCL no Curso d’água Tenente Rocha, houve uma redução no indicador DBO, o qual se manteve abaixo de 30mg/L; na média mensal, em contrapartida, os resultados da pesquisa apontaram que na opinião de 95% dos moradores entrevistados, a percepção é de que o referido curso d’água não se encontra despoluído.
Palavras-chave: Despoluição de córregos urbanos. Programa Córrego Limpo. Demanda Bioquímica de Oxigênio (DBO).
AN EFFORTS TO INCREASE STUDENT’S KNOWLEDGE ABOUT THE IMPORTANCE OF CHOOSING HEALTHY SNACKS AT KRAGAN ELEMENTARY SCHOOL, SIDOARJO
Authors: Rahmania Nima Eka Nur , Nanda Ratri Nurwanti  , Anastasya Hardyana Putri
Published: June 2023

An increasing students' knowledge through health promotion at Kragan Elementary School, Sidoarjo is a form of counseling and practice that aims to provide education about the importance of healthy snacks so that it is hoped that students can choose healthy snacks that are beneficial for growth and health. Inaccuracy in choosing snacks can result in negative impacts on health such as obesity, decreased intelligence and diarrhea. The activity was held on January 26th, 2023 at Kragan Elementary School, Sidoarjo. The target was students in grades 4th, 5th and 6th at Kragan Elementary School, Sidoarjo. Before the implementation of the activity, there is a preparation process for the activity for 1 month before the activies are carried out, starting from the selection of health education materials to submitting permits to related parties. As an evaluation of the activity attended by 90 students, the participants participated in the activity enthusiastically and conductively, the activity could be carried out smoothly and  on time.
CAPACITY BUILDING FOR FEMALE VOLUNTEERS: SRIKANDI OF EAST JAVA IN DISASTER PREPAREDNESS EFFORTS, CARDIAC ARREST FIRST AID WITH CPR
Authors: Wijayanti, S.Kep.Ns., M.Kep Dini Prastyo , Nisa Dewanti  , Tamara Nur Budiarti  , Kiki Widyasari  , Nurul Kusuma
Published: June 2023

The importance and influence of female volunteerism Srikandi East Java in disaster relief is widely recognized  to respond disaster preparedness. Cardiopulmonary resuscitation (CPR) performed by bystanders is an essential treatment for sudden cardiac arrest.  Cardiopulmonary Resuscitation  is an emergency lifesaving procedure performed when the heart stops beating. The aim of community service is to improving knowledge and skills of CPR to female volunteers Srikandi East Java confidence to help their families, communities and people in need during disasters and emergencies.  The method used in this community service activity is to provide training  CPR and councelling cardiac arrest . This activity was carried out may 2023 which was attended by 80  female volunteers  member of Srikandi East Java. The results show that the activity has achieved success according to the success indicators that have been set, namely as many as 80  female volunteers  member of Srikandi East Java attendance is 100%, participants participate in activities enthusiastically, knowledge of CPR after training and counseling increases significantly. CPR drills should be done regularly so that many female bystanders are trained.
APPLICATION OF PROBIOTIC ANTISEPSIS FOR PURULENT COMPLICATIONS IN PATIENTS WITH TYPE 2 DIABETES MELLITUS
Authors: Ioffe Oleksandr Yu. , Stetsenko Oleksandr P. , Kindzer Stepan L. , Kryvopustov Mykola S. , Tsiura Yuri P. , Prykhodko Yevhenii S.
Published: June 2023

The aim: To improve the results of surgical treatment of patients with type 2 diabetes and purulent-necrotic wounds by using probiotic antiseptics.
Materials and methods: 66 patients with type 2 diabetes and purulent-necrotic complications took part in this study. Probiotic antiseptics were used for local treatment in the experimental group (n=31), and traditional antiseptics were used in the control group (n=35). The levels of pro-inflammatory markers in the blood (IL-6, TNF-a, CRP) were studied; microscopic material was taken to study the type of cytogram during bandaging, before wound treatment with antiseptics or debridement on admission to the hospital (1st day), on the 3rd day and on the 7th day.
Results: Analysis of dynamic changes in pro-inflammatory markers between the first and seventh days proved that only in the experimental group there was a statistically significant difference (IL-6 (Р=0.004), TNF-a (Р=0.001), CRP (Р=0.018)). Detection of regenerative-inflammatory and regenerative cytogram types on the 7th day in the experimental group had a statistically significant difference compared to the control group (p=0.002 and p<0.001, respectively).
Conclusions: the use of probiotic antisepsis accelerates wound healing in patients with type 2 diabetes and purulent-necrotic complications.
INTERSECTORAL BALANCE AS A PLANNING TOOL IN THE ECONOMY
Authors:   Russian Presidential Academy of National Economy and Public Administration, Moscow, Russian Federation, Yarlykapov A. B.
Published: June 2023

The article is devoted to the application of the model of intersectoral balance in the planning of balanced and proportional development of the branches of the national economy of the country in order to achieve dynamic and progressive development of the Russian economy.
MECHANISMS OF FINANCIAL STABILITY AND SUSTAINABILITY OF ENTERPRISES
Authors:   North Caucasian Federal University Stavropol, Russia, Gorlov Sergei M. , Molchanova Regina V. ,   Saint-Petersburg State University of Aerospace Instrumentation, Saint-Petersburg, Russia
Published: June 2023

The article explores the importance of financial stability and resilience for businesses in the context of changing market conditions and volatility. The authors present a research approach aimed at identifying key variables and causes that determine the financial stability of enterprises, as well as developing risk management strategies. It summarizes external factors such as economic conditions, market trends, legal regulation and internal factors, including financial policy, asset and liability management, investment decisions, financial reporting, as important components of ensuring the financial stability and sustainability of enterprises. Particular attention is paid to financial planning, budgeting, working capital management, liquidity, debt management, credit risk, portfolio diversity and diversification, risk management and insurance, as well as the development of alternative sources of financing. The authors summarize the importance of cost optimization and operational risk management in ensuring the financial stability and competitiveness of an organization.
THE IMPROVEMENT OF ARTIFICIAL INTELLIGENCE SYSTEM TRAINING MECHANISM BASED ON X-RAY IMAGES
Authors:   Russian Customs Academy, L’yubertsy, Russia, Lonshakov Leonid M. ,   Federal Customs Service, Moscow, Russia
Published: June 2023

In this article, the main attention is paid to the problem of the quality of labeling of fluoroscopic images used in training artificial intelligence models used as part of the automatic analysis of inspection complex images in the Federal Customs Service, an improved mechanism for labeling fluoroscopic images has been developed, and an assessment of the current and useful effect from the introduction of an improved mechanism developed by the author. The analysis of the structural elements that form the quality of the inspection complex images marking and their ratio when marking the images is carried out. The results are presented visually on the matrix of the Boston Consulting Group. Guidelines have been developed for marking images of inspection complex by officials. The ways of overcoming the existing problematic issues are proposed.
HUBUNGAN STRATEGI BISNIS FASTFOOD MELALUI DIRECT MARKETING STUDI KASUS CALIFORNIA FRIED CHICKEN SUZUYA MALL RANTAUPRAPAT
Authors: Dalimunthe Ummi Nurzannah , Nasution Ade Parlaungan , Lubis Junita
Published: June 2023

The application of direct marketing can generally increase sales of products and services to consumers because these activities will directly obtain a response or feedback from consumers. The purpose of this study is partially independent variables Product Quality (X1), Product Attributes (X2), Service (X3) and Differentiation (X4) affect the dependent variable Direct Marketing (Y). The research design relevant to this research emphasizes descriptive research collaboration with a quantitative approach. The population and sample are customers who visit California Fried Chicken (CFC) Suzuya Mall Rantauprapat in the January-February 2023 period. The method of determining the population and sample generally uses Maximum Likehood Estimation (MLE), the number of samples in the survey ranges from 100-200 samples estimated based on the number of variable indicators as a whole 5 x 20 (indicators), so the sample set is 250 samples. The sampling technique uses purposive sampling (ie whoever the respondent is who kebutulan meets with the researcher at the California Fried Chicken (CFC) Suzuya Mall Rantauprapat). The scale technique used by the author chooses a Likert scale. As for data analysis techniques in solving problems with the Smart PLS v.4.0 application to predict the model tested in the study. From the results of the study it can be concluded that the variables of product quality (X1) and service (X3) have no significant effect on direct marketing and product attributes (X2) and differentiation (X4) have a significant effect on direct marketing. In addition, the findings of the research direct marketing variable has a good role as the dependent variable