bluuebunny/crossref_metadata_2025 huggingface dataset:
La inscontitucionalidad de las reformas efectuadas al COIP en el año 2023, en el ámbito de garantías penitenciarias
Authors: Moyano-Zapata Jose Luis , Vasconez-Fuentes Jose Luis
Published: October 2024

Las reformas efectuadas al Código Orgánico Integral Penal (COIP) en el año 2023 en Ecuador han suscitado preocupación debido a la posible inconstitucionalidad en el ámbito de garantías penitenciarias. Estas modificaciones legales han generado fallos contradictorios, ambigüedades en la ley y la percepción de que las instituciones están privilegiando prácticas arbitrarias sobre reglas claras. Como consecuencia inmediata, las personas privadas de su libertad han perdido varios beneficios penitenciarios, lo que sugiere una vulneración de derechos en el marco legal. El objetivo general del artículo es establecer cuáles son los principios y garantías constitucionales que se vulneran con la aplicación de las reformas del COIP en el año 2023, específicamente en lo que respecta a las garantías penitenciarias. La metodología utilizada en este estudio es de carácter cualitativo y se basa en un análisis doctrinal y jurisprudencial. El procedimiento de investigación incluye revisión bibliográfica y documental de la Constitución de la República del Ecuador de 2008 y del Código Orgánico Integral Penal (COIP) con sus reformas de 2023, el estudio de casos de fallos judiciales y situaciones prácticas que evidencian la aplicación de las reformas y sus consecuencias en los derechos de las personas privadas de su libertad y la evaluación comparativa entre la normativa reformada y los estándares constitucionales y de derechos humanos internacionales aplicables en Ecuador. La investigación se centra en responder la pregunta: ¿Las reformas al COIP en el año 2023 se contraponen con las garantías constitucionales enmarcadas en la carta magna ecuatoriana? A través de un enfoque integral que busca ofrecer un aporte científico sobre la situación jurídica de las personas privadas de libertad en relación con las garantías constitucionales y penitenciarias, proporcionando un análisis detallado y fundamentado sobre la posible inconstitucionalidad de las reformas del COIP en el ámbito de las garantías penitenciarias, mediante entrevistas a expertos en derecho constitucional que permitirá realizar una evaluación comparativa entre la normativa reformada y los estándares constitucionales y de derechos humanos internacionales aplicables en Ecuador, con el fin de contribuir a la protección de los derechos de las personas privadas de su libertad y el fortalecimiento del estado de derecho en Ecuador.
DIAGNÓSTICO TARDIO DE CARCINOMA ESPINOCELULAR ORAL: RELATO DE CASO
Authors: Andreiv Izadora , Moreira Giovana Bossi , Cortati Jamile Guimarães , Duran Natália , Oliveira Renato Victor de
Published: October 2024

O carcinoma espinocelular (CEC) é considerado uma das neoplasias malignas da cavidade oral com maior frequência de diagnóstico no mundo, representa 90% dessas neoplasias, sendo assim, considerado um problema de saúde pública. O seu desenvolvimento ocorre, na maioria das vezes, em lateral de língua, com bordas endurecidas e, no geral, assintomático. Há tendência a se desenvolver mais em homens, após a quarta década de vida, além de ter os pacientes tabagistas e etilistas como os mais afetados. O ideal é que o diagnóstico aconteça precocemente, levando em consideração que o estágio da doença em que o paciente é diagnosticado está diretamente ligado ao seu prognóstico, portanto, para que seja o mais favorável possível, deve ser feito nos estágios iniciais. Com base nisso, esse trabalho tem como objetivo apresentar um caso clínico, onde a paciente não se enquadra no perfil epidemiológico do CEC, porém, apresenta uma lesão característica do mesmo. O intuito é alertar sobre as consequências e abordagens iniciais, descrever os detalhes da anamnese, exame clínico, biópsia e diagnóstico.
EMAGRECIMENTO E HIPERTROFIA: COMPONENTES QUE ESTRUTURAM UMA BOA DIETA PARA INDIVÍDUOS COM SOBREPESO E OBESIDADE QUE BUSCAM HIPERTROFIA
Authors: Marinho Jady Cristiny Jean , Almeida Filho Stefano Guerra , Lima Lillian Tavares de
Published: October 2024

A junção de dieta e musculação pode ser uma ótima estratégia para potencializar o emagrecimento e a hipertrofia, visto que ambos podem causar impactos positivos em nossa saúde de diversas formas, sendo um deles a melhora na flexibilidade metabólica. É importante lembrar que um indivíduo só irá perder peso se estiver em uma dieta com déficit calórico, o que nunca vai ser o mesmo para todos dependendo da quantidade de gordura corporal e estado geral do indivíduo. Assim, sempre será necessário verificar o balanço calórico da dieta, distribuindo macro e micronutrientes de forma inteligente, visando otimizar tanto o emagrecimento, quanto a hipertrofia, causando uma recomposição corporal. Entretanto, cada pessoa possui determinadas necessidades nutricionais, individualidades e rotinas únicas, por isso que toda a dieta deve ser individualizada e aplicada de acordo com o contexto que o paciente vive. O que nos leva a esse estudo a passar os possíveis processos encontrados em cada indivíduo e aperfeiçoamento de dieta equilibrada. Como metodologia foi utilizado o método de revisão bibliográfica da leitura científica, no período entre 2012 a 2024. A combinação apresentada e uma estratégia dotada de planejamentos cuidadosos de dieta e de treinos acompanhados levando em consideração a prevenção e controle de patologias. Nesse âmbito a nutrição contribui para uma maior eficácia de melhoria do bem-estar e saúde.
Evaluación de la dispersión del glifosato en cultivos: enfoque ecológico y económico con papeles hidrosensibles y método enzimático
Authors: Aparicio Villanueva Milton Sael , Marrugo Negrete José Luis
Published: October 2024

Implementar un proceso experimental para el muestreo, cuantificación y deriva de glifosato en aspersiones manuales utilizando parches de algodón, el método de inmunoadsorción ligada a enzimas y papales hidrosensibles (WSP) en el municipio de Ciénaga de Oro, Córdoba, Colombia, utilizando papeles hidrosensibles (WSP) y el método de inmunoadsorción ligada a enzimas en muestras de algodón. Metodología: La aspersión se realizó manualmente con una bomba de fumigación de 18 L. Se ubicaron 132 estaciones de muestreo con WSP y parches de algodón en un terreno de 50 x 20 metros. Los papeles hidrosensibles se analizaron mediante el software “DepositScant” y las muestras de algodón con el método enzimático. El análisis estadístico se realizó con el software Statgraphics Centurion versión XVI aplicando análisis de varianza, de distribución y pruebas significativas (p<0.05). Resultados. Se reportaron concentraciones promedio de glifosato de 1,50 ± 0,16 µg/L para la aspersión; 0,65 ± 0,14 µg/L en la post aspersión diurna y 0,07 ± 0,02 µg/L para la post aspersión nocturna. De acuerdo con los WSP se descarta el efecto deriva que se produce por la acción del viento. Conclusión. Se detectó glifosato en el 48,4% de las muestras analizadas para los procesos de aspersión, post aspersión diurna y nocturna. Las concentraciones de glifosato en la zona variaron considerablemente evidenciando una persistencia en el ambiente.
Variación de las coberturas y usos del suelo del municipio de Pueblo Bello - Cesar en los años 2003, 2014 y 2024, a partir de la vocación y capacidad de uso del suelo y su relación con los conflictos de uso de suelo
Authors: Del Toro Pérez Andrés Felipe , Petro Rosario Beatriz Elena , López Cantillo Alejandra Vanessa , Pérez Osorio Isaías , Villadiego Lorduy Jorge Rafael
Published: October 2024

Los cambios en la cobertura terrestre son en gran medida el producto de la intensa actividad humana a lo largo de la historia, estos cambios de cobertura y uso del suelo derivan en procesos como la fragmentación del paisaje, que a su vez alteran los ciclos hidrológicos y degradan el suelo. En este estudio, se analizaron los cambios de cobertura y uso en el municipio de Pueblo Bello, Cesar en los años 2003, 2014 y 2024 y, específicamente, se identificaron, mediante sensores remotos los cambios en la cobertura y uso, también se especificó la capacidad y vocación del mismo y finalmente, se explicó cómo estos se relacionan con el conflicto de uso del suelo en la zona de estudio. En este municipio, los cambios se atribuyen a la deforestación y conflictos de uso principalmente, pues el porcentaje correspondiente a áreas abiertas, sin o con poca vegetación para el año 2003 fue de 8.8%, en el año 2014 aumentó hasta 15.7% y finalmente en el 2024 ascendió notoriamente hasta 22.3%, generando así una mayor superficie. En el transcurso de la investigación se analizan los cambios de cobertura y uso a partir de la interpretación de imágenes satelitales (Landsat 7 y 8) posteriormente clasificadas con el fin de obtener resultados cartográficos referentes a cobertura y uso de suelo. Con los cuales se demostró que la cobertura de bosque, se ha mantenido por encima del 70% del área total por lo que es la más predominante en el municipio.
THE CHALLENGES AND CONSEQUENCES OF THE (IN)VISIBILITY OF THE HOMOSEXUAL TEACHER IN THE ACADEMIC CONTEXT
Authors: da Costa Elvio Carlos , Osti Andréia
Published: October 2024

In the current context of education, the (in)visibility of the homosexual teacher continues to be a complex and often neglected issue. The general objective of this study is to survey the representations of teachers of Professional Education from a renowned institution in the State of São Paulo about the homosexuality of teachers within the academic environment. The design of this research was carried out through a bibliographic research. This is a qualitative and descriptive research. A questionnaire was used as an instrument for data collection, consisting of 03 open questions, applied through the Microsoft Forms form to teachers, structured in line with the theoretical framework and the objectives outlined for this investigation. To this end, 80 professionals working in professional education participated in this research, as follows: 80 teachers (called P01 to P80) in different hierarchical positions of 15 State Technical Schools contemplating two Regional Centers of the State of São Paulo. The first question asked to the participants was whether or not it is possible to identify a homosexual teacher who is not self-declared. For 36 (45%) of the participants, it is possible to identify a homosexual person, 23 (29%) say they cannot, 20 (25%) point out that they may be able to identify it, and only 1 (1%) say they do not know how to answer. The second question refers to the participants' representations of self-declared homosexual teachers in the school environment, in this sense, 58 participants defend that self-declared homosexual teachers are equal to heterosexual teachers in all senses, including deserving respect like any human being. The teacher's professional competence is considered the most important factor for nine people. When asked about the fact that a teacher is openly homosexual may cause some kind of discomfort, we found that the majority 67 (84%) say they do not cause any discomfort, 5 (6%) say they do, and 8 (10%) report that they maybe. In short, the main challenges and consequences of the (in)visibility of homosexual teachers in the academic context include veiled or explicit discrimination and prejudice on the part of colleagues, students, and even academic management, which can affect their emotional and professional well-being. In addition, invisibility can limit opportunities for career advancement for homosexual teachers, such as access to leadership positions, research funding, and academic recognition.
Transformative Physical Attribution of Mixed-use Project Development in Bangkok Metropolitan Area, Thailand
Authors: Klinmalai Siwaporn
Published: October 2024

Mixed-use developments encompass both large-scale and mega projects, strategically located in various zones including the inner city, central business district, as well as suburban and nearby areas. These projects serve as critical indicators of the prevailing direction of urban development in the region. While the underlying concept of mixed-use project development is grounded in the principles of sustainability and the enhancement of overall quality of life within the urban environment, it is essential to underscore that these projects do not operate in isolation. They exist within the broader context of the pre-existing urban landscape and are intertwined with the local communities in which they are situated. The aim of this study is to examine transformative changes of uses in mixed-use projects within the Bangkok Metropolitan area, Thailand. These changes involve the attributes and coordination among different uses within the projects. The chronological study undertaken in this research employs a methodological approach aimed at unveiling the historical evolution and prevailing trends in the development of mixed-use projects. The research findings indicate a discernible pattern wherein a majority of these projects have expanded from the city center towards suburban and outlying areas. These suburban areas are notably targeted for future urban development initiatives. Importantly, these areas continue to maintain medium to high population densities and include zones designated for residential and industrial purposes, which in turn have substantial implications for land pricing and investment strategies. Considering these findings, urban planners are presented with a valuable opportunity to proactively prepare and adapt city planning strategies to align with this transformational shift in urban development patterns. Such proactive measures are essential to ensure that the city’s growth and development remain sustainable, balanced, and responsive to the changing needs and dynamics of its residents and stakeholders.
Organized Catalytic Converter Theft: An Exploratory Social Network Analysis of a Nationwide Catalytic Converter Theft Network
Authors: Meaux James , Jones Nathan
Published: October 2024

This article provides a mixed methods social network analysis case study of a nationwide catalytic converter theft network. Catalytic converter theft is woefully understudied, and this article seeks to contribute an empirical case study and argues for the application of social network analysis as a law enforcement investigative strategy to better combat organized crime catalytic converter theft. The findings included actors with high levels of betweenness centrality, indicating they were in a brokerage position and that police targeting of them would be highly disruptive to these types of networks. Targeting these high betweenness centrality core buyers, despite network structures that attempt to insulate them, would also help to disrupt demand or raise the costs of these illicit markets; potentially weakening demand for catalytic converter theft.
Assessing the Knowledge Gap in Paediatric Emergency Management among Primary Healthcare Workers in Zaria, Nigeria
Authors: P. O. Suberu , K. O. Obohwemu , V. Y. Soyobi
Published: October 2024

Paediatric emergencies remain a significant cause of mortality in Nigeria, particularly in rural areas where primary healthcare centres (PHCs) often serve as the sole source of medical care. This study aimed to assess the knowledge gap among healthcare workers in PHCs in Zaria regarding the management of common paediatric emergencies.
A cross-sectional descriptive study was conducted among 139 randomly selected healthcare workers in Sabon Gari and Zaria Local Government Areas. A pre-tested questionnaire was used to collect data, which was analysed using SPSS version 21.
Results revealed a generally low level of knowledge among healthcare workers regarding both the causes and treatment of common paediatric emergencies. Only a small percentage of respondents demonstrated adequate knowledge in these areas. A statistically significant association was found between academic qualifications and knowledge levels.
These findings underscore the urgent need for targeted interventions to improve the skills and knowledge of healthcare workers in PHCs. Collaborations between academic institutions and local health departments can play a crucial role in organising regular training programs to address these deficiencies and enhance the quality of care provided to children in need.
Investigation of the Synergistic Anti-pyretic and Anti-inflammatory Activity of Sonchus wightianus DC, Paracetamol and Indomethacin Combination in Rat Models
Authors: Gurung Sushil , Sarkar Mayukh , Samanta Sairashmi , Chettri Rohit , Chhetri Royan , Mahato Ankit Kumar , D R Nishanth , Kumar Mahesh
Published: October 2024

Introduction: In conventional Indian medicine, several plants have long been utilized to treat various ailments. Among these herbal species, Sonchus wightianus DC is known for anti-inflammatory and antipyretic effects attributed to compound found in its leaves such as fatty acid methyl esters, sterol and triterpenoids. Induced pyrexia and inflammation in animal models serves to investigate the potential synergistic interactions between traditional herbal remedies and standard medication.
Aims and Objectves: Thus, this research aimed to evaluate the anti-pyretic and anti-inflammatory properties of methanolic extract obtained from Sonchus wightianus DC leaves tested alone and in combination with classic anti-inflammatory agents using the Carrageenan paw edema and anti-pyretic agent using yeast-induced pyrexia in Wistar rats.
Methods: Soxhlet extraction was used to obtain the methanolic extract. Inflammation was induced by a 1% (w/v) carrageenan injection, while 20% Brewer's yeast triggered pyrexia in male Wistar rat. The antipyretic activity was evaluated by taking the body temperature at various hours, while the anti-inflammatory activity was assessed by measuring the paw and cytokines (TNF-α, IL-6, IL-1β).
Results: The research investigation discovered that the extract of Sonchus wightianus DC along with varying doses of Indomethacin and Paracetamol, considerably reduced raised body temperature and avoided inflammation, exhibiting percentage inhibition. The study further revealed that at a dosage of 300 mg/kg of the plant extract, 300 mg/kg plant extract combined with Paracetamol (150 mg/kg), and 300 mg/kg plant extract combined with Indomethacin (10 mg/kg), there was a marked reduction in paw edema and pyrexia in the experimental models. Moreover, the extract was found to substantially lower serum levels of key inflammatory mediators, including IL-1β, IL-6, and TNF-α.
Conclusion: These findings indicates that Sonchus wightianus DC extract has potential therapeutic benefits in managing inflammation and fever, especially when combined with standard drugs like Paracetamol and Indomethacin.
Límites de la democratización municipal en Chihuahua: la incidencia de los cabildos en el proceso de democratización y el presupuesto participativo
Authors: Acosta Varela Nolberto
Published: October 2024

Estudiar el proceso de democratización municipal en Chihuahua México como parte de un proyecto nacional, nos permite comprender la situación que prevalece en los gobiernos municipales de una entidad federativa que ha experimentado alternancias político-electorales en un marco de transición y diferentes escenarios jurídicos constitucionales para una mayor democratización de los gobiernos municipales. Este trabajo, está focalizado en una de las 32 entidades federativas del país, pero comparte en lo general condiciones muy similares de funcionamiento. El objetivo es evidenciar cómo a través de cuarenta y un años, varias reformas políticas y alternancias entre partidos políticos, el gobierno municipal se continúa eligiendo bajo un formato del viejo régimen sin que haya una adecuada democracia representativa, menos aún, la democracia participativa que se promueve a nivel nacional. Para esta indagatoria se revisa el proceso histórico nacional y su relación con el funcionamiento del municipio, entendido éste, como la célula básica del gobierno. También se analizan las consecuencias de gobiernos emanados a partir de una reforma constitucional que posibilita la elección de gobiernos y representantes populares sin necesidad de pertenencia a un partido político. En Chihuahua, se eligieron varios ayuntamientos bajo esas nuevas reglas constitucionales, pero no tuvieron trascendencia, quedando totalmente fuera de las boletas electorales en 2024. Se elige a un alcalde y un número de regidores que no representan a una población específica, sino al conjunto de la ciudadanía. Para ello, revisé bases de datos generadas por los organismos electorales, tanto nacional, como local.
Valoración prenatal: evaluación de habilidades clínicas en alumnado universitario de Enfermería a través de lista de cotejo
Authors: Bernal Becerril Martha Lilia , Godínez Rodríguez María de los Ángeles , Sotomayor Sánchez Sandra Magdalena , Eisenring Marín Michelle
Published: October 2024

La enseñanza a través de la simulación constituye una herramienta indispensable para fortalecer habilidades en la aplicación de tecnologías de cuidado, y contar con instrumentos que permitan evaluar la adquisición de dichas habilidades clínicas es importante ya que esta herramienta de enseñanza aproxima al alumnado a situaciones lo cercanas a la realidad, permite la integración teoría-práctica y fomenta la capacidad de toma de decisiones, la seguridad para el paciente y mayor calidad en la atención. Por lo anterior, se planteó la presente investigación con el objetivo de diseñar y validar un instrumento de evaluación (lista de cotejo) para emplearse en entornos de aprendizaje simulado aplicables para la enseñanza de la valoración prenatal. Método: El estudio fue diseñado en dos fases, la primera consistió en un estudio psicométrico cuantitativo-descriptivo para validar la lista de cotejo a través de jueceo de expertos, y la segunda fase consistió en un estudio cuasiexperimental para implementar un escenario clínico simulado y evaluar conocimientos y habilidades adquiridas para la valoración prenatal en alumnado de 5º semestre de la licenciatura en enfermería y obstetricia. Resultados: se obtuvo un instrumento diseñado y validado estadísticamente, con un Alpha de Cronbach de 0.836 con lo que se considera como un instrumento válido para su aplicación en la práctica de la valoración del control prenatal. Conclusiones: el instrumento diseñado y validado es un recurso educativo útil para profesorado y alumnado de enfermería con posibilidad de mejora y ajuste acorde a las circunstancias que se quieran plantear.
Creencias de hombres y mujeres de la Universidad de Morelia, Michoacán, sobre el machismo en la vasectomí
Authors: Domínguez García Martha Dalia , Valenzuela Gandarilla Josefina , Pérez Guerreo Ruth Esperanza , Barragán López Ma. Guadalupe , Chávez Carbajal Gricelia
Published: October 2024

El uso de los métodos anticonceptivos tradicionalmente se ha atribuido a la mujer, limitando la participación del hombre debido a posturas machistas, temor a perder su virilidad, disminuir su hombría, a perder el deseo y potencia sexual, al desconocimiento de las ventajas de la anticoncepción para hombres, entre ellos la vasectomía. Objetivo. Evaluar las creencias sobre el machismo en la vasectomía en hombres y mujeres de una universidad de Morelia, Michoacán. Estudio con enfoque cuantitativo, diseño no experimental, descriptivo y transversal. Muestra no probabilística de 200 universitarios (hombres n = 114 y mujeres n = 77) seleccionados a conveniencia. Instrumento: cuestionario de creencias y actitudes hacia la vasectomía con 27 items y cuatro dimensiones, escala de respuesta de cinco opciones. Se empleó estadística descriptiva y programa SPSS. 88.5 % eran solteros, 28.4 % cursaron la carrera de enfermería, 53.5% estudian y trabajan, 74.5 % ya iniciaron vida sexual y 94.5 % no tienen hijos. Hubo bajo nivel de creencias sobre el machismo en la vasectomía en la escala total (60.5 %) y en todas las dimensiones, disminución de la virilidad (71.5 %), beneficios (50.5 %), valoración negativa a la cirugía (59.5 %) y percepción negativa (69 %). La participación del hombre en la anticoncepción es cada vez mayor, sin embargo, se requiere incidir en las nuevas generaciones para mitigar los mitos y creencias relacionadas con la vasectomía, considerando que la evidencia muestra que es un procedimiento sin riesgos, ni repercusiones negativas en la salud del hombre.
Current status of wastewater treatment through large-scale treatment wetlands in the State of Veracruz, Mexico
Authors: Martínez-Aguilar Karina Elizabeth , Marín-Muñiz José Luis , Álvarez-Hernández Luis Manuel , Delfín-Portela Elizabeth , Zamora-Castro Sergio A.
Published: October 2024

The use of treatment wetlands has increased globally in the last twenty years. In the State of Veracruz, Mexico, CONAGUA has only registered six wetland-based treatment plants. However, recent research has revealed the existence of additional wetland treatment systems in operation that were not listed in the CONAGUA inventory. The main objective of this study is to diagnose the current situation of wastewater treatment in the State of Veracruz, Mexico, and identify the large-scale treatment wetlands that exist in the region. The study will focus on the design and implementation characteristics of these wetlands. The research is qualitative and descriptive, based on publications between 2000 and 2023 from Google Scholar and databases published by CONAGUA. The information review process used a content analysis technique to identify the geographical location of the wetlands, their installation area, the type of wetland, the type and volume of treated water, the vegetation used, and the year of installation. The results identified 12 large-scale treatment wetlands currently in operation in the State of Veracruz, Mexico, which have different design characteristics. The main variations are in the type of plants used. Some of these wetlands have been in operation for periods ranging from 1 to 17 years, but there is no updated information regarding their current functioning. Thus, future research is suggested to focus on the situational diagnosis of these systems years after their installation.
Asymptotic behavior of SMOTE-generated samples using order statistics
Authors: Kamalov Firuz
Published: October 2024

Imbalanced datasets often lead to biased machine learning models that underperform on minority classes. The Synthetic Minority Over-sampling Technique (SMOTE) addresses this by generating synthetic samples for the minority class. Despite its empirical success, the theoretical properties of SMOTE remain underexplored. This paper investigates the asymptotic behavior of SMOTE-generated random variables using order statistics. We establish that, as the sample size n increases, the SMOTE-generated variable Z conditioned on the k-th order statistic X(k) converges in mean to X(k). Additionally, the expected value of Z converges to the expected value of the original random variable X as n approaches infinity. The results are derived under the assumption of left-bounded support for X. Our findings provide a theoretical foundation for SMOTE, demonstrating that it preserves key statistical properties of the original data distribution in large samples.
Pengaruh Media Sosial, Citra Destinasi Dan Persepsi Harga Terhadap Keputusan Berkunjung Di Dunia Fantasi (Dufan)
Authors: Sulistio Luna , Talumantak Ricky
Published: October 2024

Penelitian ini bertujuan untuk mengetahui pengaruh media sosial, citra destinasi dan persepsi harga terhadap Keputusan berkunjung di Dunia Fantasi. Populasi dalam penelitian ini adalah  pengunjung yang kebetulan ada atau tersedia ditempat penelitian. Dalam penelitian ini Teknik sampling yang digunakan yaitu accidental sampling dengan memperoleh responden sebanyak 100 reesponden. Metode  survei  untuk mengumpulkan  data  dalam  penelitian  menggunakan kuesioner terstruktur, untuk analisis  hubungan  hipotesis dalam model penelitian ini yaitu analisis regresi linier berganda serta bantuan software SPSS versi 20. Survei untuk penelitian ini dimulai pada bulan Febuari 2024 hingga maret 2024 di Dunia Fantasi. Hasil pada penelitian ini menunjukkan bahwa  media sosial, citra destinasi, persepsi harga secara partial berpengaruh signifikan positif terhadap Keputusan berkunjung di Dunia Fantasi dan media sosial, citra destinasi, persepsi harga secara simultan berpengaruh signifikan terhadap Keputusan berkunjung di Dunia Fantasi
Lineamientos para implementar la inteligencia artificial en el derecho privado
Authors: Perrilla Granados Juan Sebastián Alejandro
Published: October 2024

El derecho privado encuentra su fundamento en los derechos reales, los cuales están sujetos a procesos que se pueden sistematizar para ser gestionados a través de la inteligencia artificial. Para estos efectos se propone una estructura de cuatro pasos que vincule de manera dinámica las fuentes, los títulos, los modos y los derechos reales. Estos pasos pueden ser estructurados desde una programación tecnológica de flujo, condicional y, generalmente, silogística. Así, en este artículo se presenta una propuesta basada en el enfoque de estructuras de las disciplinas y que permite generar derivaciones tecnológicas en contextos específicos.
Ravulizumab for adults with generalized myasthenia gravis: a plain language summary of three studies
Authors: Aguirre Florencia , Andrade Renata
Published: October 2024

What is this summary about?

Generalized myasthenia gravis (often shortened to gMG) is a rare health condition that causes muscular weakness. This summary gives an overview of three published articles that report the results of research studies of a medicine called ravulizumab, a treatment approved for adults with gMG. These studies are:

The CHAMPION MG study.

The CHAMPION MG extension study.

A study of how the body processes and responds to ravulizumab (known as pharmacokinetics and pharmacodynamics).

These studies looked at how effective and safe ravulizumab is for people with gMG.

What were the results?

Overall, participants with gMG who received ravulizumab showed a significant and rapid improvement in their muscle strength and ability to do daily activities. These improvements were sustained for up to 60 weeks of treatment. Ravulizumab was well-tolerated overall, and no-one in the study had a meningococcal infection (a type of bacterial infection preventable with vaccination). Results from the pharmacokinetic and pharmacodynamic study support the use of ravulizumab every 8 weeks to maintain improvements in gMG.

What do the results of the study mean?

Ravulizumab can be considered as a treatment option for adults with gMG who are appropriately protected against meningococcal infection before starting treatment. The drug, administered every 8 weeks, improves muscle strength and daily performance. These positive effects have been observed to persist over a long period of time.
Redes Móveis e Veiculares em Cidades Inteligentes
Authors: Bittencourt Luiz F. , Madeira Edmundo R. M. , Villas Leandro
Published: October 2024

Redes móveis também podem interconectar veículos, facilitando o gerenciamento do tráfego e o atendimento de emergências. Nesse sentido, este artigo discute como o desenvolvimento de algoritmos e mecanismos de gerência de recursos para redes móveis e veiculares pode ajudar na melhoria da qualidade de vida em centros urbanos.
Ein weiterer Erdrutschsieg: Die britischen Parlamentswahlen vom 4. Juli 2024
Authors: Sturm Roland
Published: October 2024

After 14 years in opposition, Labour is back in power . A governing party in conflict with itself, big and unresolved economic problems, and a Scottish National Party that managed to steer itself in a political cul-de-sac made change possible . The size of change is not least the result of the first-past-the-post electoral system and its disproportionality effects . These allowed the Labour Party to take 63 .4 per cent of the seats in Parliament with only 33 .7 per cent of votes . The British party system is more divided than ever before . The Liberal Democrats experienced a political comeback as alternative to the Conservatives, and the Green party made progress as an alternative to Labour . Reform UK, the party of the right-wing populist Nigel Farage, came third in the electoral contest with regard to vote totals . The lower turnout is surprising given the broader and stronger competition among parties . It reflects widespread disillusion among voters concerning politics, and the distancing of a growing number of people from the political process .
Blinde Flecken in Einrichtungen der Sozialen Arbeit
Authors: Brizay Ulrike
Published: October 2024

Ausgehend von einer Studie zur psychosozialen Versorgung von Menschen mit Fluchterfahrung widmet sich der folgende Beitrag der institutionellen Diskriminierung in sozialen Einrichtungen. Diese betrifft nicht nur geflüchtete Menschen, die in Beratungsstellen an der Sprachbarriere scheitern, sondern auch queere Jugendliche in Jugendeinrichtungen, Menschen mit eingeschränkter Mobilität in Nachbarschaftshäusern oder nicht-traditionelle Familien in Familienzentren. Die Gefahr der institutionellen Diskriminierung in Einrichtungen der Sozialen Arbeit verweist auf die Bedeutung einer diversitätssensiblen und diskriminierungskritischen Organisationsentwicklung.
Проект по экстенсивному чтению как средство формирования иноязычной коммуникативной компетенции и правовой культуры студентов-юристов
Authors: Полякова С.В. , Полякова П.С.
Published: October 2024

в статье рассматривается проект по экстенсивному чтению как дидактическое средство формирования иноязычной коммуникативной компетенции (ИКК) студентов юридического факультета. Анализируются особенности организации проекта по экстенсивному чтению на примере адаптированных художественных произведений на занятиях по иностранному языку и самостоятельной работы студентов. Для проекта по ЭЧ характерна направленность на активизацию критического мышления, профессионального мышления, закладывания основ профессиональной культуры, укрепления профессионального самосознания студентов направления «Юриспруденция». Цель исследования – оценка эффективности проекта ЭЧ в качестве средства реализации стратегии развития иноязычной коммуникативной компетенции студентов. В ходе исследования анализируется система интерактивных заданий, разработанных на основе адаптированного романа «Адвокат» и ее реализация в проекте по экстенсивному чтению. В результате внедрения проекта ЭЧ и анализа обратной связи студентов-юристов выявляется общее положительное влияние на совершеннствование речевой, языковой, социокультурной и учебно-познавательной компетенций обучающихся, а также на формирование их правовой культуры.

the article considers the project on extensive reading as a didactic means of forming foreign language communicative competence (FLCC) of students of the Faculty of Law. The features of the organization of an extensive reading project are analyzed using the example of adapted works of art in foreign language classes and independent work of students. The ER project is characterized by a focus on activating critical thinking, professional thinking, laying the foundations of professional culture, and strengthening the professional self-awareness of students in the field of Jurisprudence. The purpose of the study is to evaluate the effectiveness of the ER project as a means of implementing a strategy for the development of students' foreign language communicative competence. The study analyzes a system of interactive tasks developed on the basis of the adapted novel “The Lawyer” and its implementation in an extensive reading project. As a result of the implementation of the ER project and the analysis of feedback from law students, the overall positive impact on the improvement of speech, language, socio-cultural and educational and cognitive competencies of students, as well as on the formation of their legal culture, is revealed.
Семантика форм именительного падежа в арабском и русском языках
Authors: Мухаммад А. , Аль Д.Д.
Published: October 2024

исследование было проведено с целью определения общих и отличительных черт использования именительного падежа в арабском и русском языках через анализ лингвистических значений. Эта статья актуальна, потому что впервые проводится столь глубокий анализ именительного падежа в арабском и русском языках, а также их сравнение. Теоретическая и практическая значимость данного исследования заключается в том, что оно способствует лучшему пониманию обоих языков и полезно для преподавания иностранных языков, перевода и культурного обмена. Были сравнены и проанализированы семантические функции именительного падежа в русском и арабском языках. Исследование охватывало различные функции именительного падежа в выражении грамматических отношений и смысловых значений существительных и прилагательных в обоих языках. Также включался анализ семантических ролей именительного падежа в различных грамматических контекстах, таких как подлежащее, сказуемое, обращение, атрибуция и сравнение. Это исследование предоставляет более глубокое понимание глобальных языковых механизмов и их роли в различных культурных и языковых контекстах. Полученные результаты способствуют улучшению преподавания иностранных языков, подготовке переводчиков и укреплению культурного взаимопонимания между носителями арабского и русского языков. Исследование помогает лингвистам, преподавателям и студентам понять тонкости использования именительного падежа, что позволяет лучше применять его в языковой и коммуникативной практике.

the study was conducted to determine the common and distinctive features of the use of the nominative case in Arabic and Russian through the analysis of linguistic meanings. This article is relevant because it is the first time such an in-depth analysis of the nominative case in Arabic and Russian has been conducted, as well as their comparison. The theoretical and practical significance of this study lies in its contribution to a better understanding of both languages and its usefulness for teaching foreign languages, translation, and cultural exchange. The semantic functions of the nominative case in Russian and Arabic were compared and analyzed. The study covered various functions of the nominative case in expressing grammatical relations and semantic meanings of nouns and adjectives in both languages. It also included an analysis of the semantic roles of the nominative case in various grammatical contexts, such as subject, predicate, address, attribution, and comparison. This study provides a deeper understanding of global linguistic mechanisms and their roles in different cultural and linguistic contexts. The results obtained contribute to the improvement of foreign language teaching, the preparation of translators, and the strengthening of cultural understanding between speakers of Arabic and Russian. The research helps linguists, teachers, and students understand the nuances of using the nominative case, allowing for better application in linguistic and communicative practice.
Прецедентные имена в афроамериканском и китайском хип-хоп дискурсе
Authors: Белёва Д.Г. , Гавриленко О.В.
Published: October 2024

в данной статье рассматриваются прецедентные феномены как актуальные в познавательном и эмотивном плане сигналы специфики определенной лингвокультуры. Прецедентные имена как результат эмотивно-образного восприятия единичных элементов окружающей действительности активно употребляются в своей фиксированной форме в песенном дискурсе в условиях афроамериканской и китайской лингвокультур. Цель данной статьи – выявить и рассмотреть прецедентные имена в афроамериканском и китайском современном хип-хоп дискурсе на родном языке. В двух лингвокультурах все выявленные имена формируют прецедентные поля, в составе которых могут быть выделены темы «успех», «религия», «социально-политические проблемы». В афроамериканском дискурсе добавляется тема «внешний вид», а в социально-политических проблемах своей объемностью выделяется блок «расизм». В китайском хип-хоп дискурсе обнаруживается тема «патриотизм». Прецедентные имена ввиду изменяющихся социокультурных условий оказываются подвижными феноменами. Тема расизма является самой активной в афроамериканском хип-хоп дискурсе, регулярно пополняясь новыми единицами – результатами столкновений в реальной действительности на почве расовой дискриминации и сегрегации. В Китае эта тема оказывается невостребованной, но здесь появляется «патриотический рэп», риторика которого направлена на восхваление своей страны, ее богатого культурного наследия и достижений.

the article is devoted to precedent phenomena as significant cognitive and emotive signals of peculiarity of some linguoculture. Precedent phenomena are the complex sings, they are the result of emotive and schematic perception of singular elements of the world, they are actively used in their fixed form in song discourse of African-American and Chinese cultures. The article is aimed to collect and analyze precedent phenomena of African-American and Chinese modern hip-hop discourse in the English and Chinese languages. Collected name of these two linguocultures are organized into precedent domains, which include the following topics: “success”, “religion”, “social and political issues”. In the African-American discourse the topic “appearance” is added and the group “racism” which is especially representative among the rest of social and political issues. The Chinese hip-hop discourse comprises the topic “patriotism”, which is not found in African-American, and the topic “religion” expands into “religion and philosophy”. Precedent names turn out to be flexible owing to changing social and cultural surrounding. The topic of racism is the most active and relevant in the African-American discourse, it is regularly supplied with new items which are the result of real conflicts owing to race discrimination and segregation taking place in the real world. In China this topic is irrelevant, but China has so called “patriotic rap”, which is aimed to glorify their own country, its rich cultural and historical heritage and achievements.
Restoring agricultural soils
Authors:   Parliamentary Office of Science and Technology, Tresise Megan , Wentworth Jonathan
Published: October 2024

Changes to the management of agricultural soil could contribute to improving the ability of soils to produce crops, as well as to wider benefits including mitigating future climate change. This POSTnote summarises the state of England's agricultural soils and evaluates soil stewardship opportunities. Soil indicators that could be used for monitoring in policy frameworks and incentives relating to soil restoration are explored.
Table 3: Some Drug Interactions with DAAs for HCV Infection
Authors:   Editors from The Medical Letter
Published: October 2024

Table 3: Some Drug Interactions with DAAs for HCV Infection
İÇ DENETİM DANIŞMANLIK FONKSİYONUNA BİR ÖRNEK: BİREYSEL PERFORMANS YÖNETİMİ
Authors: Başdemir Atak Ayşe
Published: October 2024

İç denetim, bilginin araştırılmasına, yayılmasına ve yönlendirilmesine odaklanan bir metodoloji aracılığıyla kurum ve paydaşların mevcut iş sürecinden elde edeceği faydayı en üst düzeye çıkaracak öneriler sunan bir danışmanlık rolüne sahiptir. Danışmanlık rolü sayesinde iç denetçiler kurumlarına önemli katkılar sunmaktadır. İç denetimin danışmanlık fonksiyonunun en temel başarısı ise, önerilen iyileştirmelerin uygulanması ile ölçülmektedir. Bu kapsamda bu araştırmanın amacı, örnek seçilen şirketin bireysel performans yönetim sürecine ilişkin gerçekleştirilen danışmanlık faaliyeti ile iç denetimin kurumlarına katkı sağlayabileceğini, bir uygulama pratiği olarak ortaya koymaktır. Araştırmada örnek seçilen şirketin iş yapma kültürü, süreçleri icra eden çalışanların bilgi seviyesi, deneyimi, yetkinlik düzeyi, şirketin içinde bulunduğu çevre gibi etmenler analiz kapsamına alınmış, gözlem, belge inceleme, mülakat gibi nitel araştırma yöntemleri kullanılmıştır. Ayrıca, örnek seçilen şirketin bireysel performans sürecinin, en iyi uygulamalara uygunluğuna yönelik bir benchmark çalışması yürütülmüştür. Öncelikle performans yönetimi ile ilgili kavramlar ve temel unsurlar tanımlanarak örnek uygulama çerçevesinde vakıf olunan bireysel performans yönetim sürecinin genel literatür içindeki yeri, uygulamanın zorlukları ve riskleri değerlendirilmiştir. Ardından, insan davranışını olumlu yönde etkileyen dünyadaki yeni yaklaşımlardan örnekler vermek suretiyle araştırmaya örnek seçilen şirket uygulamasında geliştirilmesi gereken hususlara ve pratikte fayda sağlayacak uygulanabilir önerilere yer verilmiştir.
Emerging pollution, antimicrobial resistance, and the applicability of biochar adsorbents: A comprehensive study in African water systems
Authors:   , Ripanda Asha
Published: October 2024

The impacts of antimicrobial resistance (AMR) extend far beyond clinical settings, permeating into agriculture and the economy, precipitating dire consequences such as compromised treatment efficacy, diminished agricultural productivity, and substantial economic burdens. This study aimed at investigating the occurrences, composition and distribution of antimicrobial pollutants and further study the remediation of lamivudine and ciprofloxacin from synthetic solutions onto JS biochar using a response surface methodology (RSM) based on optimal design. Results indicates identification of Klebsiella spp., Proteus spp., Pseudomonas aeruginosa, and Escherichia coli and were resistant to at least 1 of the tested antibiotics, indicating their presence in wastewater and urban receiving waters. Higher proportion of multi-drug resistance (MDR) in Escherichia coli,83%, than Klebsiella spp., 68.5% and Pseudomonas aeruginosa, 20%. All bacterial species highly resisted penicillin (P), while showed less resistance to gentamycin (CN). The isolates contained sulphonamide resistant genes (Sul 1 and Sul 2), tetracycline-resistant genes (Tet A, Tet B – 1, and Tet D) and β-lactamases (bla CTX-M and bla SHV), and Escherichia coli harboured more MDR genes (39%), followed by Klebsiella spp., 22%. JS biochar was amorphous, with porous, rough surface and potential functional groups for adsorption of contaminants. Further, results indicate increase in carbon content of JS biochar from 64.25-87.93 (wt.%) and nitrogen from 2-2.29 (wt.%) when calcination temperature increased from 400℃ to 600℃, with highest surface area of 261.2 m2/g and adsorption capacity of 555.55 mg/g for ciprofloxacin and 400 mg/g for lamivudine. Lamivudine removal had a model regression coefficient R2 , adjusted R2, and predicted R2 of 0.9934, 0.9761, and 0.8340, respectively. While for the ciprofloxacin model, the regression coefficient R2, adjusted R2,and projected R2 were 0.9968, 0.9891, and 0.8023, respectively. The maximum experimental removal efficiency of lamivudine and ciprofloxacin onto JS biochar reached 84.9% and 94.46%, respectively. Isotherm data indicated lamivudine and ciprofloxacin adsorption onto JS biochar followed the Freundlich isotherm. The study identified antimicrobial residues as well as the presence of antibiotic resistant bacteria in water. It also demonstrated the effectiveness of JS biochar adsorbent for remediation of lamivudine and ciprofloxacin from synthetic water, indicating future improvement and use in mitigating antimicrobial resistance.