bluuebunny/crossref_metadata_2025 huggingface dataset:
Applying Neutrosophic Iadov Technique for assessing an MDD-based approach to support software design
Authors:   Department of System Analysis and Telecommunications, Southern Federal University, Taganrog, Russia, Silega Nemury , Aguilar G. F. Castro ,   Facultad de Ingeniería, Universidad Católica de Santiago de Guayaquil, Guayaquil, Ecuador ; Facultad de Ciencias Matemáticas y Físicas, Universidad de Guayaquil, Guayaquil, Ecuador, Alcívar I. A. Martillo ,   Facultad de Ciencias Matemáticas y Físicas, Universidad de Guayaquil, Guayaquil, Ecuador, Colombo K. M. Faggioni ,   Facultad de Ciencias Matemáticas y Físicas, Universidad de Guayaquil, Guayaquil, Ecuador
Published: October 2022

Performing a correct architectural design is essential to satisfy the quality requirements of a software. In this phase, the high-level components that will compose the system, as well as their relationships, are defined. Since the architects must struggle with complex and challenging tasks in this phase, providing them with advanced and helpful tools and methods is suitable. For example, MDD-based approaches are a valuable means to deal with the complexity during the software development process, particularly during the architectural design stage. However, despite the notable benefits of this type of approaches, the architects are often sceptical about adopting new technologies. Hence, before formally adopting new methods or tools, it is suitable to consider the opinion of those using them. In that sense, this paper aims to describe the results of an assessment of an MDA-based approach to support the architectural design. This assessment was carried out applying the Iadov neutrosophic technique. This technique has been extensively applied in a wide variety of domains to analyze the satisfaction level of potential users of different proposals. The results indicate a high satisfaction level of potential users of the assessed approach.
Different Types of Operations on Neutrosophic Graphs
Authors:   School of Computer Science and Engineering (SCOPE), VIT-AP University, Inavolu, Beside AP Secretariat, Amaravati AP, India, Dey Arindam
Published: October 2022

The fuzzy graph theory uses a substantial and important role in modelling and structuring many optimization problems. DIfferent type of uncertainties exist in most of the optimization problems in real lIfe scenarios due to indeterminate and incomplete information and it is a challenging task for the expert to design those optimization problems applying fuzzy graph. To design the incomplete, uncertainty and vagueness in graphical optimization problems, several extensions of graph theoretical ideas are proposed. The idea of neutrosophic graph plays an important role to manage the uncertainty, linked with the indeterminate and incomplete data/information of any optimization problem. In this manuscript, we present the idea of regular neutrosophic graph, strong neutrosophic graph, bipartite neutrosophic graph, regular neutrosophic graph, and regular strong neutrosophic graph. We also introduce six different operations on neutrosophic graph, viz., cartesian product, composition, join, direct product, lexicographic and strong product.
An exploration of nursing students’ stress, coping, and quality of life
Authors: LeBlanc Caroline A. , Prude Susan B. , Bordelon Ashley M. , Mars Dell G.
Published: October 2022

Objective: The purpose of this phenomenological study was to identify stressors nursing students experience and examine the impact of stress on quality of life. A secondary aim was to identify coping mechanisms nursing students use to manage stress and to explore the effectiveness of these coping strategies.Methods: Purposive and snowball sampling were used to recruit eight students from a baccalaureate nursing program in the southeastern United States. One on one interviews were conducted using a semi-structured interview guide. Data were analyzed using Colaizzi’s method of data analysis.Results: Three themes emerged and were identified as (a) the Culture of Nursing School, (b) Nursing School Impacts Quality of Life, and (c) Emotion-Focused Coping. The sub-themes identified with Nursing School Impacts Quality of Life included Personal Lives Altered and Fear of Failure. Within Emotion-Focused Coping emerged two subthemes, Misery Loves Company and Light at the End of the Tunnel.Conclusions: The present study sheds light on the stressors nursing students experience Many students feel unprepared and become occupied with the fear of failure, which interferes with concentration and academic performance. Stressful situations in nursing school are unavoidable, therefore students must develop effective coping strategies. Faculty need to incorporate coping education into the curriculum to produce resilient, successful nurses. Fostering adaptive coping strategies may help decrease burnout and improve physical and mental wellbeing in nursing students.
Penerapan Metode Analythic Hierarchy Process untuk Pengambilan Keputusan Pemilihan Desain Jembatan Kereta Api
Authors: Wibowo Heriyanto , Nugroho Sinung Tri
Published: October 2022

Padalarang - Purwakarta line track is a very crowded but potential track since it connects Jakarta - Bandung. Argo Parahyangan train and freight train are passing through this track. Therefore, it is crucial to build double track lane. However, it is difficult to execute due to a wide and deep river which requires a new bridge with a complex high cost construction. That is the reason why, an in-depth evaluation of the bridge design is needed. In selecting the bridge design, the Analytical Hierarchy Process  was used as the selection method. The method would applied a four-level developed structure: the first level was the goal of choosing the Optimum Bridge Design, the second level was the people involved, the third level was the evaluation criteria, the last level was the alternative bridge to be built. The data was taken from the questionnaires filled by six respondents of the railway bridge's construction experts. The results show that the order of the bridge's design selection is as follows: 0.395 for concrete bridges; 0.213 for steel arch bridges; 0.199 for steel frame bridges; and 0.194 for cable bridges.
Evaluasi Kapasitas Eksisting Pelabuhan Bongkar Batubara Terhadap Peningkatan Ukuran Tonase Kapal
Authors: Naiborhu Maria Angelin
Published: October 2022

Coal unloading ports at a steam power plant (PLTU), the size of barge or ship is determined based on the needs of coal consumption each month and the safety factors that considers period of downtime due to weather factor. The percentage of downtime when the design is calculated to be distributed in a period of time can last for several weeks and cause a break in the supply of coal to the power plant in a long period of time. Regarding this condition, it is necessary to use bigger ship capacity. The size of ships served in some PLTU must be evaluated. This article discusses a case of port capacity evaluation in one of PLTU in Southern Coast of Java if it was able to serve a ship with bigger size. An evaluation to the capacity of pier pole structure was done by using SAP2000 software and the evaluation of pier dimension, fender and bollard capacity, as well as the depth and the area of existing turning basin that have been done by using port design standards. The result of the evaluation is an early indication for the size of ships which still can be served by the existing port PLTU.
Desain dan Konstruksi Pemecah Gelombang dengan Sisi Miring
Authors: Naiborhu Maria Angelin , Purnawanti Yani Nurita , Kumalasari Silvia Dewi
Published: October 2022

Sloping breakwater is the type of breakwater requires large volume of rock and protection armor. Material increase during construction is often occur due to several factors. The main influenced factor is wave condition during construction. The main purpose of this research is to investigate the increasement of the materials due to breakwater profile changes caused by wave action during construction stage based on literature study of real construction data of breakwater construction at one of the thermal power plant in South Java Sea. This research is expected to provide an overview for designers to determine the cross-profile of a breakwater which is constructible and select the appropriate construction method to reduce the risk of excessive material increase during construction, especially for breakwaters located in deep and rough sea.
Major approaches to melatonin and nutrients regulation in the bone regeneration process with exosomes and microRNAs: a systematic review
Authors: Leite Danillo Gomes
Published: October 2022

Introduction: Bone diseases comprise a large group of common diseases, including fractures, osteoporosis, and osteoarthritis that affect a large number of individuals. Without intervention, the prevalence of osteopenia is projected to increase to 64.3 million Americans and that of osteoporosis to 11.9 million by the year 2030. Melatonin exerts numerous physiological effects, including the induction of anti-inflammatory and antioxidants, resetting circadian rhythms, and promoting wound healing and tissue regeneration, participating in the maintenance and regenerative processes of bones and cartilage. Objective: A systematic review was carried out to present the state of the art of melatonin regulation, mesenchymal stem cells, exosomes, microRNAs, and nutrients in the bone regeneration process. Methods: The systematic review rules (PRISMA) were followed. The search was carried out from July to September 2022 in the Scopus, PubMed, Science Direct, Scielo, and Google Scholar databases, using scientific articles from 2019 to 2022. The quality of the studies was based on the GRADE instrument and the risk of bias was analyzed according to the Cochrane instrument. Results and Conclusion: A total of 126 articles were found. A total of 59 articles were fully evaluated and 46 were included in this systematic review. Considering the Cochrane tool for risk of bias, the overall assessment resulted in 9 studies at high risk of bias and 24 studies that did not meet the GRADE. Most studies showed homogeneity in their results, with I2 =97.8%>50%. The symmetrical funnel plot does not suggest a risk of bias between small sample-size studies. Based on the results, melatonin has important functions in regulating the regenerative activities of mesenchymal stem cells that modulate, together with nutrients, the activities of exosomes and microRNAs in the bone regeneration process.
Parental Attachment, Peer Influence and Adolescent Sexual Behavior at Vocational High School Trenggalek Regency
Authors: Meidy safitri Shafira , Faizah Zakiyatul , Dwilda Ferdinandus Euvanggelia
Published: October 2022

Introduction: Adolescence is a transitional phase from childhood to adulthood characterized by a heightened curiosity and courage to take risks. SDKI data from 2012 and 2017 showed an increase in cases of adolescents who had had premarital sexual intercourse, with the breakdown of cases in adolescent boys by 4.5% then increasing to 8% and in adolescent girls by 0.7% increasing to 2%. Objective: this study is to determine the relationship between parental attachment and peer influence with adolescent sexual behavior. Method: The type of research is correlational analytics with a cross-sectional approach. The study was conducted at SMKN 1 Pogalan, Trenggalek Regency in June 2022. The population used was grade 11 students of SMKN 1 Pogalan with a sample of 86 people. Sampling using simple random sampling. Data analysis used the spearman rho test with a 95% confidence level. Results and Discussion: Based on correlational tests, results were obtained that the variables of maternal attachment (p=0.002), father's attachment (p=0.001), and peer influence (p=0.000) had a value of p<0.05. Conclusion: this study shows there is a relationship between parental attachment and peer influence with adolescent sexual behavior in Trenggalek District Vocational High School
Comparative Study: Use Of 0.9% Normal Saline Irrigation Liquid and 10% Povidone-Iodine in The Process of Laparatomy Sectio Caesarea Operation in Hospital
Authors: Kurnia Dedi
Published: October 2022

Introduction: Operating Area Infections (IDO) is part of Healthcare-Associated Infections (HAIs) which is a global problem and reaches at least 9% (3%-21%) of 1.4 million clients worldwide. This figure was reported by the World Health Organization (WHO) from the results of a survey in 14 countries covering 28,861 clients in 47 hospitals. Based on the results of a survey every year, millions of people undergo surgical treatment so that surgical intervention covers about 13% of the total life or DALYs (Disability-Adjusted Life Years). Objective: irrigation fluids normal saline 0.9% and povidone-iodine with the wound healing process after laparotomy sectio caesarea. Methods: The design used in this study is an expost facto comparative, namely research that compares the presence of one or more variables in different samples with a retrospective approach. Results and Discussion: The results of the research analysis showed that there were significant differences between the two irrigation fluids, but according to several theories and research, the differences were due to differences in composition and characteristics of the irrigation fluids that had been used. However, the irrigation fluid can still be used for intraoperative irrigation. Conclusion: This study shows that there is a statistical difference between the two types of irrigation fluids, namely normal saline 0.9% and povidone iodine on the wound healing process by having different characteristics and fluid composition
Antimicrobial and antibiofilm activity of Ferula spp. growing in Erzurum
Authors: Topçu Şimal , Arslan Elif , Çobaoğlu Şeymanur , Yazıcı Ayşenur , İncekara Ümit
Published: October 2022

This study investigated the antimicrobial and antibiofilm activities of Ferula species (sp.) obtained from Erzurum province.
Antimicrobial activity against Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Enterococcus faecalis,
Candida albicans, and Candida tropicalis were determined by agar well diffusion assay. Ethyl acetate extract showed
antimicrobial activity against S. aureus, and methanol extract showed antimicrobial activity against E. coli and C. albicans with
a zone diameter of 21, 18, and 15 mm, respectively. The extract's minimum inhibitory concentrations (MIC) were 16, 32, and
32 μg/mL ml for S. aureus, E. coli, and C. albicans, respectively. Furthermore, it was determined for the first time that Ferula
sp. extracts were effective against biofilm formations of S. aureus and C. albicans. In the light of these results, we think that
extracts of Ferula sp. contain potential candidate molecules against biofilm-associated infections, and further characterization
studies are needed.
MINERAÇÃO DE TEXTOS ARTICULADA AO USO DO SISTEMA IRAMUTEQ: UMA INVESTIGAÇÃO DAS DISSERTAÇÕES DE MESTRADO APRESENTADAS AO PPGEFIS/IFES
Authors: Gagno Júnior Fernando , Duarte Marcelene Alves , Correa Iasmin Crespo , Gagno Maria Lúcia Neiva Bastos
Published: October 2022

O objetivo geral deste ensaio é investigar as dissertações de mestrado defendidas no Programa de Pós-Graduação no Ensino de Física (PPGEFIS), mestrado profissional, entre os anos de 2014 a 2020. O intuito é o de identificar o seu perfil pedagógico e classificar os métodos e metodologias mais utilizados, a fim de auxiliar o trabalho docente e, assim, fomentar futuros planejamentos para o ensino e pesquisa em Física. Desse modo, foram analisados 40 resumos de dissertações defendias e aprovadas. Como forma de auxiliar o trabalho investigativo do pesquisador, associou-se a análise textual artesanal ao uso de sistemas informáticos, referente à filosofia de sistemas livres embarcados pelo rigor técnico-científico. Este trabalho de pesquisa está fundamentado sob a ótica da Análise Textual Discursiva (ATD), conforme apontado por Galiazzi e Sousa (2019), em que as palavras têm significado e sentido, sempre passíveis de uma maior compreensão. Além disso, a fim de acompanhar o uso dos sistemas informáticos de grandes volumes em textos, foi utilizado o conceito de mineração de texto, proposto por Feldmam, que descreve a forma como se pode extrair informações a partir de uma seleção de textos, o corpus textual. A ideia principal é converter dados qualitativo em quantitativos, por meio de ferramentas matemáticas e estatísticas. Nesse sentido, foram utilizadas 3 lexicográficas básicas do sistema: Estatística Descritiva, Análise Fatorial Correspondente (AFC) e Nuvem de Palavras. Os resultados (AFC) indicaram proximidades e distanciamentos entre os orientadores. Tais indicações são fontes de recursos para desenvolver o trabalho investigativo; análise do gráfico de nuvem de palavras corroboram os resultados apontados pela AFC.
The Three Key Pillars That Support the Adult Learning Process
Authors: Parkin Elissa
Published: October 2022

This reflective essay was written within the context of tertiary study and scholarly practice, reflecting on the similarities noticed between what supports and encourages an adult’s capacity for learning, and the prerequisites, circumstances, and environments which facilitate individual therapeutic healing. In this essay the author reflects on three key pillars which have most supported her own learning process through an undergraduate subject studied at Ikon Institute, while also making connections to how these pillars served as foundational to the author’s capacity to be with her own growth and therapeutic healing process – a process which is hypothesised to be is deeply intertwined with the adult individual’s capacity to learn. The essay synthesises several key concepts and related themes (nervous system regulation, metacognition, and deep listening) within mental health fields and therapeutic practice and presents a coherent exploration of how these concepts intertwine to best support the learning process.
Assessment of anemia among rural children in Kaduna State, Nigeria by determining hemoglobin and serum ferritin levels
Authors: Yasmin Andrew Nuhu , Obazee Dorcas Yetunde , Dada Micheal Olugbamila , Oyewande Azeezat Abimbola , Alabi Bolanle Yemisi , Faith Ajani Olumide , Conteh Ishata , Sanni Felix Olaniyi , Abiodun Olaiya Paul , Bartholomew Ochonye Boniface , Adaran Tolu , Gwa Zachary Terna , Afelumo Olaide Lateef , Okwose Innocent
Published: October 2022

Background and objective: Children in the developing world are vulnerable to iron deficiency (ID) and iron deficiency anemia (IDA) because they grow fast and consume diets low in iron. Thus, this study assessed anemia in children aged 6 - 12 years in rural Nigeria, using hematological indices and serum ferritin as diagnostic tools.

Materials and methods: This cross-sectional study was carried out in two primary schools in Kumin Masara Kataf village in Kaduna state, Nigeria. School children aged 6 - 12 years were enrolled. Personal information and laboratory data were collected. Hemoglobin and serum ferritin concentration was estimated to determine anemia and iron status. Data analysis was done using IBM-SPSS Inc., Chicago, IL, USA, version-25.0.

Results: A total of 191 school-age children aged 6 - 12 years were enrolled in the study. The overall serum ferritin was 16.51±5.20 mg/L, but the children aged 6 - 9 years had significantly (p<0.05) higher serum ferritin (17.23±5.57 mg/L), compared to children aged 10-12 years (15.62±4.62). The mean hemoglobin concentration and serum ferritin were significantly (p<0.05) more elevated among males (11.17±2.53g/dl and 19.01±5.06 mg/L, respectively) than females (10.18±2.46 g/dl and 14.03±4.02 mg/L respectively).The overall rate of anemia was 51.3%, while IDA was 70.4% (69/98). Iron deficiency was present in 47.3% (44/93) children. Also, anemia was significantly (p<0.001) more prevalent among females (66.7%), than males (35.8%), and a higher proportion of females (87.5%) than males (26.2%) were iron deficient (p<0.05), but more males (44.1%) had IDA, p<0.05.

Conclusion: This study found a high prevalence of IDA and ID among rural school children in Nigeria. It is recommended that healthcare providers focus more on preventing IDA right before childhood.

IMC J Med Sci. 2023. 17(1): 006. DOI: https://doi.org/10.55010/imcjms.17.006

*Correspondence: Andrew Nuhu Yashim, Haematology and Blood Transfusion Department, National Hospital, Abuja, Nigeria. Email: yashimnuhuandrew@gmail.com
Resection of peripheral arteriovenous malformation in the arm with deltoid muscle and basilic vein
Authors: Salazar Carhuamaca Claudio
Published: October 2022

Las malformaciones arteriovenosas son potencialmente el tipo de malformación vascular más agresiva y difícil de tratar. Se reporta el caso de una paciente de 25 años que se interviene por presentar recidiva de malformación arteriovenosa en miembro superior derecho a nivel del brazo pulsatil que le ocasiona dolor al movimiento (estadio II de Schobinger) y estadio angiográfico IIIb de Cho-Do, con antecedente de resección de malformación arteriovenosa en la misma ubicación en los 6 años previos. Se resolvió con resección en bloque de angioma, del músculo deltoides y la vena basílica.
ANTIBACTERIAL AND ANTIBIOFILM ACTIVITIES OF Swietenia macrophylla King ETHANOLIC EXTRACT AGAINST FOODBORNE PATHOGENS
Authors: CHE MAN CHE AMIRA IZZATI , WAN ABDUL RAZAK WAN RAZARINAH , RAJA YAHYA MOHD FAKHARUL ZAMAN
Published: October 2022

Swietenia macrophylla is known to possess several medicinal uses, however, its antibacterial and antibiofilm activities against foodborne pathogens remain not well investigated. The present work was performed to examine the phytochemical compounds, antibacterial and antibiofilm activities of S. macrophylla ethanolic extract (SMEE) against four foodborne pathogens namely, Salmonella typhimurium ATCC 14028, Escherichia coli ATCC 25922, Shigella sonnei ATCC 33862 and Pseudomonas aeruginosa ATCC 10145. The phytochemical analysis of SMEE was performed using gas chromatography-mass spectrometry while the antibacterial activities of SMEE were determined by minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) assays. On the other hand, the antibiofilm and time-killing activities of SMME were evaluated using a crystal violet assay. The result demonstrated that SMEE contained major phytochemical compounds such as olean-12-ene (27.37%), resorcinol (16.45%), 24-noroleana-3,12-diene (13.4%), and germanicol (11.50%). The MIC values of SMEE ranged from 31.25 to 500 µg/mL, while all the MBC values were found to be greater than 1000 µg/mL. At the 12 h exposure to SMEE, all the biofilms were inhibited by 50% except E. coli. Biofilm inhibitory concentration (BIC50) values of SMEE ranged between 5.19 and 42.47 µg/mL. In conclusion, S. macrophylla is a promising source of natural antibacterial and antibiofilm agents to treat foodborne diseases.
SOYBEAN AS AN ALTERNATIVE NUTRIENT MEDIUM FOR Bacillus subtilis GROWTH
Authors: ABDUL MALIK NURUL HANISAH , SIMARANI KHANOM , AZIZ MUHAMAD AFIQ
Published: October 2022

Nutrient agar is a commonly used medium for the isolation and growth of a broad range of microorganisms. The feasibility of using soybean as a base medium in the development of alternative growth media was assessed in this study. Nutrient agar was used as a standard guide to evaluating the performance of the formulated soybean agar. Bacillus subtilis was inoculated and allowed to grow on nutrient agar and soybean agar. Their growth was compared within 24 h after inoculation based on the morphology of individual colonies formed on both media and the pattern of bacterial growth. Our results showed that soybean agar had comparable performance to nutrient agar as the morphological characteristics of B. subtilis colonies formed on both media are generally identical in terms of texture, margin, optical properties, colour, elevation, and shape. However, due to the similar appearance of the bacterial colonies and the soybean agar, the colonies formed on the soybean agar were slightly larger than those formed on nutrient agar. In addition, our findings also revealed that agar strips formed the best soybean agar compared to gelatin and agar powder. Ultimately, this study has shown that locally available soybeans and agar strips can be easily formulated as an alternative to commercial nutrient agar and have great potential for bacteriological research.
ANTIOXIDANT AND ANTIMICROBIAL ACTIVITY OF CUTTLEBONE CHITOSAN AGAINST Escherichia coli, Staphylococcus aureus AND Candida albicans
Authors: MD ZAHIR MASNITA FATIHAH , IBERAHIM RASHIDAH , IBRAHIM NAZLINA , SYED MOHAMAD SHARIFAH AMINAH , RUSMIN RUHAIDA , JAILANI NOOR ATIKAH , ZULKIFLI NURUL ILLIYA ZAFIRAH
Published: October 2022

The discovery of new antibiotics for infectious diseases has become challenging due to the rise of antimicrobial resistance.Meanwhile, chitosan has been considerably used in many branches of research. It has been discovered to have some good benefitsin medicals, pharmaceuticals, and food technologies. In this study, chitosan was prepared from the cuttlebone of Sepia sp. bychemical method and analyzed by using FT-IR spectrophotometer for the confirmed presence of its functional groups. Thereare three types of reactive functional groups in the chitosan which are the amino group and primary and secondary hydroxylgroup attached to the C-2, C-3, and C-6 positions respectively. Chitosan has a high cationic property due to the presence of itsamino group. The bacteriostatic activity of chitosan occurs due to its positive charge in acidic concentration that interacts withthe negatively charged residue of carbohydrates, lipids, and proteins located on the cell surface of bacteria. The antioxidantactivity was conducted using DPPH radical scavenging assay with a chitosan concentration ranging from 0.1 to 10 mg/mL anda hydrogen peroxide scavenging assay with a chitosan concentration ranging from 0.1 to 1.6 mg/mL. The antimicrobial activityof chitosan from cuttlebone was analyzed against two different bacterial strains (Escherichia coli & Staphylococcus aureus)and a fungal strain, Candida albicans by disc diffusion and minimum inhibitory concentration (MIC) method. The results showthat through the DPPH radical assay, the scavenging activity was 59.7% at the concentration of chitosan at 10mg/mL, whilethrough the hydrogen peroxide assay the scavenging activity was 56% at the concentration of chitosan at 1.6 mg/mL. Besides,this chitosan from Sepia sp. has concentration-dependent antimicrobial activity with higher antifungal activity compared toantibacterial activity against all tested organisms and may become a potential agent for antibiotic discovery
PURIFICATION AND PARTIAL CHARACTERISATION OF A PROTEASE INHIBITOR FROM Mimosa diplotricha
Authors: ALIAS ZAZALI , RAMLI NORA ASYIKIN
Published: October 2022

Search for inhibitors to insect proteases is one of many strategies to control pests. Previous work has demonstrated successful purification of effective inhibitors from plant origin. Thus, the current study attempted to purify protease inhibitors from locally available medicinal plants. The study demonstrated that the ethanolic extracts of Mimosa diplotricha leaves caused a significant 80% reduction in bovine trypsin activity. The inhibitory property of the proteinaceous nature of the extract was reconfirmed through qualitative analysis using the detection of trypsin inhibitors on the SDS-PAGE technique. The ammonium precipitated trypsin inhibitor was purified using Hi-Trap G25 and resolved into a single band with a molecular weight of approximately 20.8 kDa. By using the Dixon plot the competitive inhibitor has a Ki value of 2.16 × 10-4 mM. The purified protein inhibited the protease extract of Chrysomya megacephala at IC50 of 28 μg/mL. The results highlighted the presence of trypsin inhibitor in Mimosa diplotricha and its potential as a pest control agent.
CHARACTERIZATION AND IDENTIFICATION OF Xanthomonas spp. ISOLATED FROM INFECTED Brassicaceae AND SELECTION OF POTENTIAL XANTHAN GUM PRODUCER
Authors: SIMARANI KHANOM , BOKHARI NUR IZLIN SHAFINAZ , MOHD SALEH HAZIQAH
Published: October 2022

Xanthomonas spp. synthesize a complex exopolysaccharide called xanthan gum, which has significant commercial value. Xanthomonas-infected vegetables exhibiting typical spot symptoms were used in this study. Isolation was done by streaking the sample suspension on the Yeast Malt agar. A colony that resembled Xanthomonas spp. was purified before a simple phenotypic test and identified using BIOLOG and 16 rRNA sequencing. The screening was done based on their performance by fermentation in a shake flask, under controlled conditions. The yield and viscosity of xanthan gum produced from each bacterium were compared to Xanthomonas campestris PV. campestris strain ATCC33913. There were 411 wild types of Xanthomonas spp. successfully isolated and ten strains were selected for xanthan gum evaluation. The results showed, the xanthan production (g/L) varied from (1.57 - 8.24) with the yield of xanthan from 0.64 to 4.71 g/g biomass. Strain C206 produced the highest xanthan gum concentration (8.24±0.20 g/L) compared to others and the control strain, ATCC 33913 (2.27±0.10g/L).   The highest yield of xanthan 4.71±0.18 (g/g biomass) was produced by strain C298 followed by strain C279 with 3.88±0.04 (g/g biomass). From our investigation, the production and yield of xanthan gum and the viscosity of the polymers were significantly dependent on the bacterial strain. Based on the stable viscosity and yield of xanthan produced, X. campestris C279 was selected for further studies on product optimization.
Cooperative Group-Based Speech Writing Training Investigation on Student Class VI SD Pulibuah Districts Raya Kahean
Authors: Mery Chris Isabella Saragih
Published: October 2022

Speech is a activity speak in front general or give a speech for express his opinion, or give an idea about something. Speech usually brought by a which give orations and statement about something things/events that are important and worthy of discussion. Speech is one of the theories of lesson language indonesian . See condition child in time now, more consequence progress technology like smartphone, it is very rare that there is direct communication between one another In real life, everyone is busy with communicating in cyberspace. When again time for them to practice speaking face to face with the other person? Reflecting on In this case, we are motivated to do service to students in order to go through In this they practice speaking formally/officially as well as train critical thinking. Because from an early age, students trained so that they are able to communicate, convince listeners against argument delivered. Result student more brave communicate with good in life daily more on situation official because communicate is wrong one capital for reach success in time front.
PENGUATAN SISTEM BERPIKIR KRISTEN BAGI PEMUDA DI GMKI KABUPATEN MIMIKA
Authors: Rungkat Jimmy
Published: October 2022

GMKI in Mimika Regency is an extra-campus student organization and is a forum for Christian youths who certainly often face various challenges from outsiders regarding Christian teachings and at the same time demand that they offer various solutions to various problems of the community and the nation from within point of view of the Christian faith. Based on that, this community service aims to strengthen the Christian thinking system of Christian youth who are members of the GMKI organization in Mimika, to equip Christian youths who are members of the Mimika GMKI organization with the basic principles of the Christian Faith in responding to challenges to Christian doctrine, and to revive the commitment of Christian youth who are members of the GMKI Mimika organization to play an active role in the church and society, and to always be sensitive and wise in offering solutions to various social problems that occur. With the method of community service through four stages, namely the preparation, lecture, discussion, and evaluation stages, the results obtained are that in general they have been able to master the Logical-Theological Christian thinking system and can be a provision to be implemented in facing various challenges to Christian teachings. They also have awareness and commitment to practice their Christian faith in playing an active role in church and society, including in criticizing or offering solutions to various problems of the nation and society.
Characteristics of Pediatric Spinal Cord Injury in South Korea: A Single-Centered Study
Authors: Kim Wooyeung , Lee Bum-Suk , Kim Onyoo , Yun Hyeyeung , Han So-Ra
Published: October 2022

Objective To determine the characteristics of pediatric spinal cord injury (SCI) in South Korea from 1990 to 2019.Methods This single-centered retrospective study included pediatric SCIs. Individuals were divided into the following five groups according to onset age: ≤5, 6–12, 13–14, 15–17, and 18–19 years. The severity of complete injury was graded according to the American Spinal Injury Association impairment scale A (AIS A). Incomplete injury was graded according to AIS B, C, and D. Pearson chi-square test was used for statistical analysis.Results Of the 267 individuals included, 216 (80.9%) had traumatic SCIs (male-to-female ratio of 3.2:1), and 51 (19.1%) had non-traumatic SCIs (male-to-female ratio of 0.7:1). In the traumatic SCI group, 192 (88.9%) individuals were ≥15 years at the time of injury (males, 78.6%). The most common etiologies of traumatic SCIs, ranging from most to least common, were accidents related to motorcycles, falls, cars, and diving. In the non-traumatic SCI group, inflammatory (33.3%) and neoplastic (25.5%) etiologies were found to be the most common ones.Conclusion We found that traumatic SCIs incidence in the pediatric population was high, particularly in male individuals aged 15–19 years. The non-traumatic SCIs mostly cause paraplegia and incomplete injury. Therefore, it can be used as a basic data for the evaluation, treatment and prevention strategy of pediatric patients with SCI.
Depression among university students during Vietnam’s fourth wave of the COVID-19 pandemic
Authors:   School of Medicine and Pharmacy, The University of Danang, Danang, 50000, Vietnam., Hieu Le Tho Minh , Triet Bui Minh ,   School of Medicine and Pharmacy, The University of Danang, Danang, 50000, Vietnam., Thach Nguyen Tan ,   School of Medicine and Pharmacy, The University of Danang, Danang, 50000, Vietnam., Vi Nguyen Thi Tuong ,   School of Medicine and Pharmacy, The University of Danang, Danang, 50000, Vietnam., Truc Tran Thi Bach ,   School of Medicine and Pharmacy, The University of Danang, Danang, 50000, Vietnam., Giang Hoang Thi Nam ,   School of Medicine and Pharmacy, The University of Danang, Danang, 50000, Vietnam., Phan Le Minh Tu ,   School of Medicine and Pharmacy, The University of Danang, Danang, 50000, Vietnam.
Published: October 2022

The novel human coronavirus disease COVID-19 has been continuing to spread around the world, causing serve economic and social consequences worldwide. From the fourth wave of COVID-19 pandemic, thousands of Vietnamese people have been infected every day, making it the biggest outbreak of COVID-19 in Vietnam. Due to the most serve wave of COVID-19 in Vietnam, the concerns about a rising mental health burden have been grown. University students who are still suffering are one of the hardest-hit subjects of the pandemic. This study aims to determine the level of depression, attitudes, and behaviours of university students in Vietnam under these circumstances. A cross-sectional online survey was conducted on nationwide students from August to September 2021. The Patient Health Questionnaire-9 (PHQ-9) scale was used to evaluate the level of depression. The difference between the percentages of qualitative variables was tested using the Chi-square test. Out of a total of 302 university students, 46.0% had depression symptoms, 6.0% and 3.6% for moderately severe and severe, respectively. 80.5% of university students adhered to the Vietnamese 5K guideline. However, 33.4% of students did not wash their hands after coughing and sneezing. Additionally, 44.7% of university students increased physical activity at home; 36.8% used electronic devices over 8 hours/day for sedentary entertainment. The findings indicate a high risk of depression and decreased physical activity among university students during the COVID-19 pandemic. It is expected that the mental health problems of Vietnamese university students during and after the pandemic should be paid an intense attention from both the government and universities to eliminate the depression of university students.
A 12 Day- Old Female Infant Diagnosed with Pelvic Osteomyelitis in the Pediatric Emergency Department
Authors:   Gazi University, Faculty of Medicine, Ankara, Turkey, Oktay Mehmet Ali , Güleryüz Okşan Derinöz ,   Oksan Derinöz Güleryüz; Pediatric Emergency Department, Department of Child Health and Diseases, Gazi University Faculty of Medicine, Ankara, Turkey., Hirfanoğlu İbrahim Murat ,   İbrahim Murat Hirfanoğlu; Neonatology Department, Department of Child Health and Diseases, Gazi University Faculty of Medicine, Ankara, Turkey., Çolak Özlem ,   Özlem Çolak; Pediatric Emergency Department, Ankara, Turkey., Güneysu Songül Tomar ,   Songül Tomar Güneysu; Pediatric Emergency Department, Ankara, Turkey.
Published: October 2022

Osteomyelitis (OM) is a bacterial disease that is very rare in newborns and has devastating consequences. Neonatal OM is seen in 1-3 in 1000 babies. We presented a 12-day-old female baby who was brought to the Pediatric Emergency Department (PED). Because she could not move her leg. She did not have fever and septic appearance and had a history of hospitalization in Neonatal Intensive Care Unit; acute phase reactants were high and radiological imaging performed gradually was consistent with OM. Our patient is the youngest patient who was diagnosed with pelvic OM upon admission to the PED. Earlydiagnosis and treatment prevent complications and sequels.
Publications trends in major anesthesiology journals: A 20-year analysis of five top-ranked journals in the field
Authors:   Department of Anesthesiology, University Hospital Erfurt, Erfurt, Germany., Koppert Stefan , Weißenbacher Michael ,   Department of Anesthesiology, University Hospital Erfurt, Erfurt, Germany.,   Section of Anesthesia and Intensive care, Department of Neurosciences, University of Bologna Bologna, Italy., Wieser Andreas ,   Department of Cardiology, GRN Hospital Jena, Jena, Germany., Zelger Christoph ,   Department of Anesthesia and Intensive Care, Kreiskrankenhaus Günzburg, Günzburg, Germany, Hermann Markus ,   Department of Anesthesiology, University Hospital Erfurt, Erfurt, Germany., Köhler Till ,   Department of Anesthesiology, University Hospital Erfurt, Erfurt, Germany., Heudorfer Ralf ,   Department of Anesthesia and Intensive Care, Kreiskrankenhaus Günzburg, Günzburg, Germany
Published: October 2022

Background: With the intention to quantify the importance of a medical journal, the impact factor (IF) was introduced. It has become a de facto fictive rating instrument of the importance of medical journals. Also, it is often used to assess the value of the individual publications within the specific journal. The aim of the present study was to analyze publication trends over 20 years in five high-ranked anesthesiology journals. Methods: The Medline (NCBI) database PubMed was used for analysis which was restricted to the following journals: 1. Anesthesiology; 2. British Journal of Anaesthesia; 3. Journal of Neurosurgical Anesthesiology; 4. Anesthesia & Analgesia; and 5. Anaesthesia. Specific publication parameters (IFs, number of pages and authors, etc.) were retrieved using the PubMed download function and imported into Microsoft Excel for further analysis. Results: The mean IF of the five journals analyzed increased significantly within the study period (1991 vs. 2010; +61.81%). However, the absolute number of case reports decreased significantly by 54.7% since 1991. The journals Br J Anaesth (12.2%), J Neurosurg Anesthesiol (51.9%), and Anesth Analg (57.2%) showed significant increases in the number of publications per year. The mean number of authors increased significantly in all the journals from 1991 to 2010 (3.0 vs. 4.3; +43.3%). Conclusions: The IF, as well as the number of articles per year and the number of authors per article, increased significantly. In contrast, the number of pages per article remained comparable during the period analyzed.
Robotic surgical management for extremely high-risk prostate cancer: case report and overview of recent literature evidences in the setting
Authors:   Urology Unit, ASST Santi Paolo e Carlo, University of Milan, Italy., Rocco Bernardo , Assumma Simone ,   Urology Unit, ASST Santi Paolo e Carlo, University of Milan, Italy.,   Urology Unit, University of Modena, Italy., Sangalli Mattia ,   Urology Unit, ASST Santi Paolo e Carlo, University of Milan, Italy., Calcagnile Tommaso ,   Urology Unit, ASST Santi Paolo e Carlo, University of Milan, Italy.,   Urology Unit, University of Modena, Italy., Micali Salvatore ,   Urology Unit, University of Modena, Italy., Moro Alessia ,   Department of Pathology, ASST Santi Paolo e Carlo, University of Milan, Italy., Cigala Claudia ,   Department of Pathology, ASST Santi Paolo e Carlo, University of Milan, Italy., Sighinolfi Maria Chiara ,   Urology Unit, ASST Santi Paolo e Carlo, University of Milan, Italy.
Published: October 2022

Radical prostatectomy is recommended as a part of the multimodal treatment of high-risk or clinically advanced non-metastatic prostate cancer (PCa). In those cases, surgery could be challenging due to the possible cancerous invasion of peri-prostatic tissues that adversely affect the exposition and dissection. Moreover, a prior hormonal therapy may alter the plane between the rectum and prostate, likely resulting in an increased rate of local complications (ie rectal perforation) [1, 2]. According to the EAU Guidelines, the definition of high-risk cancer includes a PSA value exceeding 20 ng/ml. We describe the case of a young man presenting with a PSA value of 188 ng/ml, managed through robotic radical prostatectomy (RALP) at a referral center as a part of multimodal approach.
Making of MSME Website Design as a Means of Digital Marketing in Tangerang Regency
Authors: Putrinda Tisa , Widjanarko Satria Noer , Zahar Iwan
Published: October 2022

In the era of digital transformation, information and communication technology is increasingly advanced, therefore the role of the website in a Micro, Small and Medium Enterprises business is important. The existence of a quality website design in addition to increasing the reputation and trust of consumers is also an effective and efficient marketing tool methods. Based on interviews results that have been carried out at the Habbani Boutique in Tangerang Regency, a modern and professional website design is made to improve marketing and to attract consumers broadly. The observation method is used by visiting the Habbani boutique directly to find out the product to be marketed. The results of this activity are in the form of website design https://butikhabbani.com/.
Socialization of Multiculturalism: (Strengthening Understanding of the Concept of Multiculturalism in Students of SMPN 1 Botupingge, Bone Bolango Regency)
Authors: Lukum Roni , Djaafar Lucyane , Ngiu Zulaecha , Madina Abdul Haris M. , Butudoka Sintia Rahmayanti Y. , Damiti Sudarman M.
Published: October 2022

Community service activities in the student environment of SMP Negeri 1 Botupingge, Bone Bolango Regency are carried out with the aim of: (1) Increasing nationalism attitudes through community character who carry out the tradition of multiculturalism among students in Bone Bolango Regency. This socialization concern is carried out because in several regions in Indonesia there is often friction between ethnicities, both influenced by religious, racial and cultural issues that affect national resilience. So it is necessary to socialize early to the students to be able to minimize inter-ethnic conflicts in the Bone Bolango area. (2). In addition, the purpose of this socialization is to make students able to think creatively and innovatively in solving problems faced in society if there is friction caused by provocations aimed at clashing between one tribe and another. (3). Make a contributionpositif bagi para siswa  tentang pentingnya pemahaman membangun tradisi multiculturalism in maintaining the Unitary State of the Republic of Indonesia. With this awareness, it will have a positive impact on an area in anticipating the disintegration of the nation in the form of conflicts between tribes in the Bone Bolango Regency area of Gorontalo Province.
SWOT Analysis and Strengthening Socialization for BUMDes Tetus, Kuanheum Village, West Kupang
Authors: Kodi Paul Alfred Yamba , Nulle Delviana B. , Kwen Maria Stefania Conny , Manehat Vergilius , Lau Claudia Meilin Putri , Lima Ignasius Rendino , Galung Tarsisius Andriano , Tanggu Arsinius , Reis Auria Sandra Jelia Delima Ros , Usfal Andriana Evangida , Indriani Theresia Ekawati , Malon Klaudia , Triana Anna Monica , Raga Mathilde Camelia , Teku Johanes Serafim , Ke Lomi Aplonia Nelci
Published: October 2022

Village-Owned Enterprises (BUMDes) is one of the businesses that are expected to be able to revive the economy of villages in Indonesia. In supporting one of the Ministry of Village, Development, of Disadvantages Regions and Transmigration programs, the Community service team (KKNT-PPM) Widya Mandira Catholic University (UNWIRA) Kupang did the analysis and strengthening socialization for BUMDes in Kuanheum Village, West Kupang District, Kupang Regency. In the study, there were many weaknesses and threats that the management must know of BUMDes Tetus in Kuanheum Village. There are also advantages of the BUMDes and the village and opportunities that could be optimized for the village's progress. As a direct effort, the UNWIRA KKNT-PPM team carried out socialization, including facilitated discussions with various parties that could help the development of the village economy. This program is expected to be sustained and monitored to produce optimal results for the better development of Kuanheum Village
Implementation of Markov Chain on MSME Data for QRIS Users in Medan City
Authors: Hia Elisabet Desy Yulianawati , Sinaga Marlina Setia
Published: October 2022

QRIS (Quick Response Indonesian Standard) is a non-cash payment system innovation initiated by Bank Indonesia in collaboration with the Indonesian Payment System Association. This is one response to the era of digitalization and industry 4.0. Since January 2020, Bank Indonesia has required ( implemented) QRIS for non-cash payments, especially for micro, small and medium enterprises (SMEs), because it is a sector that contributes to Gross Domestic Product. Therefore, this study is intended to predict the number of SMEs using QRIS in Medan in the future based on the Markov Chain method. The data used is the number of MSMEs that use QRIS as a cashless payment in Medan City from Bank Indonesia North Sumatra in December 2019 to June 2022. The results show that there is a balance in October 2022 with a 52.2% chance percentage with declining conditions; 30.4% with an increasing condition, and 8.7% with a strongly increasing and decreasing condition. This good accuracy is checked with Mean Absolute Percentage Error (MAPE).