bluuebunny/crossref_metadata_2025 huggingface dataset:
Meta-analysis of Correlation between Peripheral Serum MIC-1 level and Lung Cancer
Authors: Dai Lei , Wang Yongyong , Chen Mingwu
Published: December 2021

Lung cancer (LC) is a common malignant tumor with high morbidity and mortality. The development of new molecular markers and the early diagnosis of LC and the exploration of emerging targeted therapies are of great significance. Therefore, this study systematically evaluates the
correlation between peripheral serum MIC-1 levels and LC. Search PubMed, Web of Science, Medline and other databases, the search time is from the establishment of the database to July 2021. The LC group included LC patients, the Non-cancer group included patients with benign lung diseases
(BLD), and the control group included healthy people. The serum MIC-1 levels of LC group and control group, LC group and Non-cancer group were compared respectively, and the correlation between serum MIC-1 and clinical characteristics of LC patients was evaluated and analyzed, and the ROC
curve of MIC-1 in prediction of LC. Finally, 5 articles were included, including 1179 patients with LC, 109 patients with BLD, and 1020 healthy people. Meta-analysis results: the level of MIC-1 in LC group was overtop that in healthy group, and the difference was obvious [SMD=1.97, 95%CI (1.35,
2.59), PC0.00001]. The level of MIC-1 in LC group was overtop that in Non-cancer group, and the difference was obvious [SMD=382.97,95%CI (313.74, 452.19), PC0.00001]. The descriptive evaluation analyzes the correlation between MIC-1 and the clinical characteristics of LC group, and the results
show that MIC-1 has a certain correlation with the stage of LC group. The AUC of serum MIC-1 in the identification of LC group and the control group was greater than 0.5. The AUC value of MIC-1 in the diagnosis of LC was 0.851-0.906, and the best sensitivity range was 63.50%-99.00%. The best
specificity is in the range of 70.4%-95.80%. The Meta-analysis indicated that the serum MIC-1 level in LC group is overtop that in BLD and healthy people, and has a obvious correlation with LC stage staging; and the ROC curve shows that it has important significance in the diagnosis and prognosis
of LC.
Effect of Meticulous Nursing Combined with Evidence-Based Nursing on Life Quality and Psychological Status of Medical Oncology Patients after Chemotherapy
Authors: Zhang Yan , Wang Fen , Zhang JingJuan , Zhou Cheng , Huang Huimin , Yan Lanping , Wang Lihua
Published: December 2021

Objective. The purpose was to study the effect of meticulous nursing combined with evidence-based nursing on life quality and psychological status of medical oncology patients after chemotherapy. Methods. 148 medical oncology patients treated in our hospital (January 2019-December
2019) were chosen as the research objects of this study, and randomly split into control group and experimental group, with 74 patients in each group. The control group received routine nursing mode for the diseases while the experimental group received meticulous nursing combined with evidence-based
nursing mode to compare and analyze effect of the two nursing models on life quality and psychological status of medical oncology patients after chemotherapy. Results. The incidence of complications, SAS and SDS scores after interventionin experimental group were obviously lower compared with
control group (P<0.05). The KPS scores of both groups after chemotherapy were obviously higher than those before chemotherapy, and the KPS score in the experimental group after chemotherapy was obviously higher than that in the control group.The life quality scores in experimental group
were obviously higher compared with control group in generally good and good aspects, and obviously lower compared the control group in middle and bad aspects (P<0.05). Conclusion. For medical oncology patients, meticulous nursing combined with evidence-based nursing after chemotherapy
can obviously reduce complications, improve life quality and enhance recovery of physical function. Compared with routine nursing mode, this nursing mode pays more attention to the changes of psychological status, which can obviously improve the psychological status, improve their enthusiasm
and initiative to cure the diseases, improve their nursing satisfaction and facilitate the harmonious development of doctor-patient relationship.
Theoretical Logic of the Cultivation of New Professional Farmers in Tobacco Planting Industry in the New Era
Authors: Hong Lin , Yi Jia , Xujun Zhai
Published: December 2021

In the new era, new professional farmers are the new force to realize the modernization of rural agriculture, innovating the theoretical logic of cultivating new professional farmers is the inherent requirement to improve the quality and efficiency of cultivating new professional
farmers. Due to the particularity of tobacco planting methods, On the basis of explaining the connotation of the cultivation of new professional farmers in tobacco planting industry and based on three theoretical foundations, this paper probes into the internal logic of the cultivation of
new professional farmers, and constructs the theoretical framework of the cultivation of new professional farmers in tobacco planting industry. This will have important theoretical significance and practical value for speeding up the process of cultivating new professional farmers in tobacco
planting industry, ensuring the quality of cultivating new professional farmers, and promoting the increase of farmers’ income and the development of modern agriculture.
Evaluating The Connection of Behavioral Biases and Investment Decisions of Equity Market Investors Using SEM Approach
Authors: Jain Nidhi , Kesari Bikrant
Published: December 2021

Objective: The key objective of the paper is to study the magnitude of the disparity in actions between stock holders for short-term and long-term. Methods: Investor traits and how the judgement on investments and behavioral bias are interconnected are contrasted by using a systemic
model, as well as to compare relative behavioral bias variations including Framing Bias, Endowment Bias, Representative Bias, Cognitive Dissonance Bias, Self-Control Bias and Overconfidence Bias. Distinguishing evidence of behavioral characteristics that are normally related to investment
venture helps to provide assessments and confine trading techniques. Results: Between July 2020 and August 2020, the cognitive effect of investor decision-making is contrasted via test review of 300 substantive responders from deliberate Indian stock market investors. Taking into account the
structural equation modelling (SEM), a route study is carried out of the manner in which stock investment and proposed behavioral inclinations are concomitant. Conclusions: Observational outcomes suggest that the systemic path model deliberately correlates with the survey content, demonstrating
the influence of behavioral discrimination in decision-making for individual investments. Our results also indicate that short-term and long-term investors’ behavioral patterns vary substantially.
Theoretical Basis and Level Evaluation of Tobacco Planting and Green Agriculture: a Case Study in Henan Province, China
Authors: Qiqi Chen , Jinghua Wang , Yufeng Su
Published: December 2021

Objectives: As an important and traditional cash crop, tobacco plays an important role in promoting economic development. With the attention of the government, scholars and people from all walks of life to environmental protection, modern agriculture needs to be transformed. Under
the current multiple pressures of resources, market, economy and other factors, how to find a high-efficiency, product safety, resource saving, environment-friendly agricultural modernization road is very important for the development of modern agriculture. Of course, tobacco planting is no
exception. In view of this, this paper took China’ s Henan Province as an example to study its agricultural green development level and influenced factors from two angles at home and abroad. The results were showed as follows. Firstly, the green development of agriculture in Henan Province
was still at the lower middle level in China. Secondly, there were some problems in the green development of agriculture in China’ s Henan Province. Finally, the green development of agriculture in Henan Province needs to promote the construction of laws and regulations and supervision
system, increase the investment in agricultural human capital, accelerate the innovation of agricultural green science and technology, optimize industrial development and strengthen infrastructure construction according to local conditions. Further, based on the development experience of green
agriculture, on the one hand, it can provide a good green agricultural production environment for the development of tobacco industry. On the other hand, it is conducive to inspire and promote the transformation and development of all links of tobacco planting, threshing and redrying, cigarette
manufacturing, monopoly circulation and retail circulation, highlighting the characteristics of greening, technology, economy, health and safety.
The Measurement of Logistics Industry Efficiency Based on the Construction of Tobacco Transport Logistics Infrastructure
Authors: Jian Li , Lu Zhang
Published: December 2021

With the increasingly fierce market competition, China’s tobacco industry has been severely tested. At the same time, according to the latest report of global Logistics Performance Index (LPI), there is a significant difference between China’s LPI and other developed
countries, indicating that China’s logistics has low efficiency, high input and low output. How to improve the service level and operation efficiency of tobacco enterprises by strengthening the construction of logistics infrastructure network is an urgent problem for tobacco enterprises
to solve. Therefore, DEA model and Malmquist index model are adopted in this paper to measure the logistics efficiency of Chinese tobacco enterprises from the aspect of logistics infrastructure network construction. This paper analyzes the state of logistics efficiency and the reasons of low
efficiency in some economic regions and puts forward countermeasures and suggestions to improve the logistics efficiency of tobacco enterprises based on the construction of logistics infrastructure network.
Research on Risk Aversion Strategy in Financial Management of Wholesale and Retail Type Listed Companies
Authors: Hou Linfang
Published: December 2021

Objectives: In recent years, with the establishment of the socialist market economy, China has set up a number of listed companies, the development of the national economy has played an important role in promoting. However, due to the short time of listing of listed companies, it
can not form a scientific system management system like western developed countries. Methods: In the process of management, there are still some shortcomings, among which the most important is financial risk management. Financial risk management for listed companies has a very important role,
not only to ensure that its financial work reasonable system of operation, but also to promote the expansion of listed companies an important means, therefore, it must be taken seriously. Results: Based on the present situation of financial risk management of listed companies in China, this
paper expatiates on financial risk management and analyzes the shortcomings of financial risk management of listed companies in China’s wholesale and retail types, analyzes their causes in detail. Conclusion: And finally, the corporate financial risk management defects of the governance
strategy put forward the corresponding recommendations.
The Dilemma and Countermeasures of Legal Control of Atmospheric Haze and Smoke Dust Pollution
Authors: Chunling Zhang , Yumei Xu
Published: December 2021

Smoke dust is an important factor leading to haze pollution. There is no doubt about the serious impact of smoke dust pollution on public health, life and economic development. A consensus has been reached on the use of legal means to control smoke dust pollution. However, the existing
laws still have too many problems to deal with the increasingly complex smoke dust pollution. It is a must to change the regulatory objects of the current “Air Pollution Prevention and Control Law (APPC Law)”, speed up the establishment of a regional joint prevention and control
legal system, and establish local characteristic legislation in accordance with local conditions. We need establish a “three-in-one” legal system for the prevention and control of atmospheric haze and smoke dust pollution with “APPC Law” at the top, local legislations
at the bottom and regional joint prevention and control law in the middle.
Influencing Factors of School Physical Education Policy Implementation Based on AHP
Authors: Liu Xia
Published: December 2021

Objectives: AHP (Analytic Hierarchy Process) is used to analyze the influencing factors of school physical education policy implementation. Methods: Based on the established hierarchical structure model of influencing factors of school physical education policy implementation, the
importance of indicators in each level is compared in pairs, the judgment matrix is established step by step, the relative importance order weight of each level element is calculated, and the consistency test is carried out, and then the ranking of each level and the general ranking are obtained.
Results: The results show that the principal, as the first responsible person for the implementation of school sports policy, plays a directional decisive role in the implementation of school sports policy. Organizational mechanism and funding guarantee factors are necessary conditions for
the implementation of school sports policy, and school sports policy factors are a powerful driving force for the implementation of school sports policy. Conclusion: AHP provides theoretical reference for better understanding the influencing factors of school physical education policy implementation
and putting forward corresponding intervention measures.
Analysis of Manpower Capability Needs in Business Process Outsourcing (BPO) for Tobacco Industry: A Case study on BPO industry in Clark Pampanga, Philippines.
Authors: Shuo Feng , Yao Qi , Magdaraog Gualberto A.
Published: December 2021

Objectives: The study focus on the capability needs of Business Process Outsourcing (BPO) employees for tobacco industry.The study is a quantitative and qualitative research study. It used a survey questionnaire to gather data needed for analysis. The respondents of the study were
50 employees of BPO companies in Clark Pampanga Philippines,where BPO industry is a trend. The findings show an up-to-date picture of BPO industries in Clark Pampanga and an insight into BPO human resources capabilities needs for tobacco industry. It may let Tobacco companies analyze own employee
management system with increased precision. They still enabled us to define employment perspective and the challenges tobacco companies are facing, to identify the current BPO human resources capability issues and the long-term human resources trends for Tobacco industry. Together, they provide
an exact depiction for the Tobacco industry and valuable foresights to both its employees and employers.
The Efficacy of Endoscopic Treatment of Gastric Stromal Tumors and Its Prognostic Factors
Authors: Xiao Hong , Fang Xingguo , Yuan Yu
Published: December 2021

Objective: To explore the actual effect of endoscopic treatment of gastric stromal tumors and its prognostic factors. Methods: A total of 60 patients with gastric stromal tumors who were admitted to our hospital from January 2018 to January 2019 were selected. They were divided into
2 groups according to the admission order, 30 cases each. The control group underwent conventional laparotomy, and the observation group underwent endoscopic treatment. The surgical indicators, recovery time, clinical efficacy, and complications were compared between the two groups. Result:
All the surgical indicators in the observation group were better than those in the control group (P <0.05), and the recovery time of the observation group was better than the control group (P <0.05). The total incidence of complications in the group was lower than that in the control
group (P <0.05). Conclusion: Endoscopic treatment of gastric stromal tumors does have exact results, and the patients have good prognosis, fewer complications, high safety, and high clinical value.
Inspiration from the History of Chinese and Hungarian Building Ceramics Manufacturing Technology to Industrial Smoke Control
Authors: Qiang Gu , Hutter Akós
Published: December 2021

Chinese and Hungarian architectural ceramics manufacturing technology is of the same origin, and both have certain influence in the world. In particular, Zsolnay, a Hungarian architectural ceramics brand, has made breakthroughs and innovations in the production process of products
in the inheritance of more than 100 years, forming a unique architectural ceramics manufacturing technology. It can effectively reduce the concentration of flue gas particulate matter and sulfur dioxide produced in production. The historical experience of the development of building ceramic
manufacturing technology in China and Hungary is of enlightenment to the current industrial smoke control.
Mechanism of action of Yupingfeng capsule for combined allergic rhinitis and asthma syndrome via the TLR4/NF-KB pathway
Authors: Hu Xin , Deng Yongjun , Li Wenping , Zhang Zhipeng
Published: December 2021

We aimed to investigate the mechanism of action of Yupingfeng capsule for combined allergic rhinitis and asthma syndrome (CARAS) via the TLR4/NF-KB pathway. Rats were divided into normal, model, experimental and control groups. CARAS model was established through sensitization with
ovalbumin (OVA) and Al(OH)3, and intranasal instillation and atomization of OVA. Then experimental and control groups were given Yupingfeng capsules and dexamethasone at 2 mg/kg by gavage once a day for 14 consecutive days, while normal and model groups were intraperitoneally injected
with an equal dose of normal saline. Their nasal symptoms were scored, and cell apoptosis in lung tissues was observed by TUNEL staining. Serum levels of interleukin-5 (IL-5) and IL-13 were detected by ELISA, and TLR4 and NF-κB expressions in lung and nasal mucosa tissues were measured
by Western blotting. The score of nasal symptoms, levels of IL-5 and IL-13, cell apoptosis rate in lung tissues, and expressions of TLR4 and NF-KB were significantly lower in experimental and control groups than in model group (P<0.05). Yupingfeng capsule can obviously suppress the release
of inflammatory factors and the apoptosis of cells as well as relieve the symptoms of CARAS rats probably by inhibiting the TLR4/NF-κB pathway.
Resveratrol affects Proliferation, Migration, Invasion and Apoptosis of Oral Squamous Cell Carcinoma Cells by Inhibiting the WNT Pathway
Authors: He Jianfang , Chen Weixing , Liang Bing , Shen Xiaoting
Published: December 2021

Objective: To explore the mechanism by which resveratrol (RES) affects the proliferation, migration, invasion and apoptosis of oral squamous cell carcinoma (OSCC) cells through inhibiting the Wnt pathway.

Methods: Ki-67, matrix metalloproteinase-9 (MMP-9) and B-cell lymphoma-2
(Bcl-2) protein expression levels were detected by immunohistochemical staining. Tca8113 cells were treated with different concentrations of RES (0, 50, 100 and 200 μmol/L) and divided into control, low-dose RES, medium-dose RES and high-dose RES groups. EdU staining,Transwell migration
and invasion assays and Annexin V-FITC/PI double-staining were employed to determine cell proliferation, migration, invasion and apoptosis, respectively. E-cadherin and N-cadherin mRNA expression levels in cells were analyzed by RT-qPCR. Wnt1,β-catenin and glycogen synthase kinase-3β
(GSK-3β) protein expression levels were detected by Western blotting.

Results: Ki-67, MMP-9 and Bcl-2 were positively expressed in OSCC tissues, with higher rates than those in normal oral mucosal tissues. RES significantly inhibited the proliferation, migration and invasion
ability of Tca8113 cells, down-regulated the expression levels of N-cadherin mRNA and Wntl, β-catenin and GSK-3β proteins, promoted apoptosis, and up-regulated E-cadherin mRNA expression level dose-dependently (P<0.05).

Conclusion: RES can inhibit the proliferation,
migration and invasion of OSCC cells and promote apoptosis possibly by inhibiting the Wnt signaling pathway, providing a potential target for targeted therapy of OSCC.
An Empirical Study on the Impact of Team Entrepreneurship Passion on the Tobacco Products Entrepreneurial Performance of New Ventures: Mediating Effect Test Based on Bootstrap Model
Authors: Yuyan Shen , Limin Ke , Qian Yan
Published: December 2021

In this paper, following the research logic of Emotion/Feature-Behavior-Result, the focus is put on how the entrepreneurial passion of interactive-oriented teams in the tobacco products entrepreneurial can improve corporate performance by affecting entrepreneurial learning. The multiple
regression method is used to test 238 valid questionnaires of new ventures, and the Bootstrap model is used to verify the mediating effect of entrepreneurial learning according to the multiple mediating effect analysis method proposed by scholars. The results show that: (1) The entrepreneurial
passion of the team will affect the tobacco products entrepreneurial process of the new venture team, and the team with high passion atmosphere is more likely to improve the performance of the new enterprise. As a strong positive emotion experienced by the entrepreneurial team in their entrepreneurial
activities, can not only influence the entrepreneurial team to identify with their entrepreneurial identity sharing, but also promote the growth of enterprises. (2) There is a significant mediating effect of exploratory learning and exploitative learning in the process of the impact of team
entrepreneurial passion on the performance of the innovator but no significant difference in the mediating effects of the two. Entrepreneurial passion drives the tobacco products entrepreneurs to make a strong emotional commitment to the new innovator and invest much effort, and entrepreneurial
learning is an effective way to help solve the problem of the new innovator. The research results can help to further interpret the mechanism of the role of the tobacco products entrepreneurial enthusiasm on the performance of innovators, expand the mediating factors between the two from psychological
to behavioral factors, enrich the research on the performance promotion mechanism of new innovators, promote the organization learning behavior combined with entrepreneurship research, and also provide references and suggestions for the tobacco products entrepreneurs to improve their entrepreneurial
performance through learning behaviors.
Effect Of Comprehensive Assessment of Nursing Mode on The Care Ability of Family Members and Quality of Life of Patients with Acute Heart Failure
Authors: Wang Lei , Ye Chen , Liu DongMei , Xu ZhenZhen
Published: December 2021

Objective To explore the effect of comprehensive assessment of nursing mode on the care ability of family members and quality of life of patients with acute heart failure. Methods 118 patients with acute heart failure treated in our hospital were randomly divided into two groups:
control group (n = 59) treated with routine nursing intervention and study group (n = 59) treated with comprehensive nursing mode intervention. Care was initiated at the time of admission until discharge. Family care, changes in cardiac function, quality of life, compliance, satisfaction,
and self-management, 6-minute walk test (6MWT), and New York Heart Association (NYHA) classification were compared between the two groups. Results The scores of family care ability in the study group were lower than those in the control group (P=0.000). After nursing intervention, the levels
of CO and LVEF in the study group and the control group were higher than those before intervention (P<0.05), and the levels of LVEDD and HR in the study group were lower than those in the control group (P=0.000). The scores of qualities of life in the study group were higher than those
in the control group (P=0.000). The compliance rate in the study group was higher than that in the control group (P=0.002). The satisfaction degree in the study group was higher than that in the control group (P<0.05). The score of self-management in study group was higher than that in
control group (P=0.000). The 6MWT level at discharge in the study group was higher than that in the control group after intervention. The odds of NYHA functional class II in the study group were higher than that in the control group. The odds of classes III and IV were lower than that in the
control group, but the difference had no statistical significance (P=0.087). Conclusion: Comprehensive assessment of nursing mode intervention in patients with acute heart failure is beneficial to the improvement of the patient’s family’s nursing ability and quality of life, as
well as the improvement of cardiac function, the improvement of the patient’s compliance, satisfaction, the level of 6MWT and NYHA functional classification.
Analysis of quality control group of departments on improving effect of PICC maintenance quality in outpatient children with tumor
Authors: Yi Qingmei , Li Xi , Cheng Tingtin , Hou Xiaofen , Li ZhiGuo , Xiao Pin
Published: December 2021

To explore the clinical effect of quality control group of departments on improving PICC maintenance quality in outpatient children with tumor. Methods: A total of 4100 children with tumor who were treated in our outpatient department of intravenous therapy from January to December
2020 were divided into observation group (July to December 2020: after the establishment of quality control department) and control group (January to June 2020: before the establishment of quality control group of departments). In the control group, conventional PICC treatment management and
maintenance measures were used. In the observation group, quality control group was used to manage, and moreover, the PICC maintenance quality, the incidence rate of PICC-related risk events and the level of PICC maintenance knowledge and satisfaction evaluation were compared between the two
groups. Results: (1) Comparing the PICC maintenance quality between the two groups, the rate of absence of PICC maintenance during the course of tumor management in the observation group (1.14%) was significantly lower than that in the control group (4.00%), and there was significant difference
in the PICC maintenance quality between the two groups (P<0.05). (2) Comparing the relative indexes of children with tumor: Before intervention, there was no significant difference in the relative indexes of children with tumor (PICC maintenance knowledge level) between the two groups (P>0.05),
but after intervention, the relative indexes of children with tumor (PICC maintenance knowledge level, and service evaluation recognition degree) in the observation group were significantly higher than that in the control group (P<0.05). (3) Comparing the probability of PICC-related risk
events between the two groups: In the course of tumor management, PICC-related complications were observed in the observation group (3.59%, 3.18%), which were significantly lower than those in the control group (11.95%, 11.37%) (P<0.05). Conclusion: The application of quality control group
of departments in the management of PICC in outpatient children with tumor has obvious clinical effect. It can effectively improve the level of maintenance knowledge and service satisfaction of family members, optimize the quality of maintenance, reduce the rate of lack of maintenance and
risk related to PICC, and is worthy of being popularized in clinical practice.
Research on Online Scene Teaching Mode of Tobacco Picking Decision Tree Construction Process Integrating Deep Learning
Authors: Shuili Zhang , Yi Zhao , Kexin Zheng , Jun Zhang , Fuchun Zheng
Published: December 2021

Objectives: In view of the characteristics of online teaching during the coronavirus pandemic and the importance of practical teaching in training students’ skills in the process of graduate education, this paper proposes an online scene teaching mode that takes projects as
the carrier and integrates with deep learning. In order to meet the demand for information and communication engineering professionals in the big data context, the whole teaching process is divided into four stages: Topic selection, Teaching project setting, online teaching interaction and
teaching evaluation. In the teaching process of Python Data Analysis Foundations, the project “establishment process of tobacco picking decision tree based on information gain” is taken as the teaching case. Prior knowledge and references are pushed through the cloud platform before
class, and The scene of tobacco picking affected by the weather is set in the online classroom to guide students to seek solutions to problems, and the results are presented with graphics to assist students to summarize, and then reset the scene to promote knowledge transfer, so as to integrate
deep learning into the teaching process, and modify the corresponding stages according to the teaching evaluation results. The content of the scene is gradually increased from easy to difficult, from simple to complex, and from least to most, gradually increasing the difficulty, which enhances
students’ learning interest and sense of achievement. Meanwhile, students’ initiative to participate in curriculum research further strengthens the effectiveness of the course in serving scientific research, which has a certain value of popularization and application.
Relationship between Lactase Activity and Intestinal Flora Structure
Authors: Zhang Ying , Huang Mingjian , Chen Jianfeng , Wang Shuyuan , Xu Jian
Published: December 2021

To analyze and explore the relationship between lactase activity and the structure of intestinal flora in infants under 1 year old. Method: Our hospital selected 60 infants and young children in the Haizhu Maternity and Child Health Hospital from August 2019 to September 2020 as
the research objects. The infants in the experimental group were diagnosed as lactose intolerant infants, the control group were normal infants, and the experimental group and control group had 30 cases each. The relationship between lactase activity and intestinal flora structure. Result:
The experimental group had fewer beneficial bacteria in the intestinal tract than the control group, but improved lactase activity by correcting the structure of the intestinal flora and alleviating symptoms of lactose intolerance. Conclusion: Infants and young children are prone to non-infectious
diarrhea, and the causes are more complicated, but most of them are related to lactose intolerance. When infants and young children develop lactose intolerance, it is necessary to pay attention to the lack of beneficial bacteria in the intestinal tract. Targeted supplementation of probiotics
(such as Lactobacillus reuteri, Clostridium butyricum, etc.) can correct the intestinal flora, improve lactase activity, and relieve symptoms of lactose intolerance.
Effect of Granulocyte Colony-Stimulating Factor Combined with Erythropoietin on Chronic Granulocytic Leukemia with Anemia and Its Effect on Nutritional Status
Authors: Tong GeLe , Xu Liusha , Leng Yanqi , Wu Pang
Published: December 2021

Objective: To investigate the clinical effect of granulocyte colony-stimulating factor combined with erythropoietin on chronic granulocytic leukemia with anemia and its effect on nutritional status. Methods: 60 patients of chronic granulocytic leukemia of our hospital with anemia
induced by maintenance chemotherapy were randomly divided into two groups. Patients in the control group received routine treatment, while patients in the observation group received basal treatment with granulocyte colony-stimulating factor and erythropoietin. The nutritional status before
and after treatment as well as the immune function and the incidence of blood transfusion and adverse events were compared between the two groups. Results: There was no significant difference in hemoglobin, hematocrit, nutritional status and immune function between the two groups before treatment
(P>0.05). Those after treatment were significantly higher than that before treatment (P<0.05). After treatment, the percentage of CD4* cells in the control group was significantly higher than that before treatment (P<0.05), but the percentage of CD8* cells and CD47/CD8* cells did
not change significantly (P>0.05). After treatment, the concentrations of IgA, IgM and IgG in the observation group were significantly higher than those before treatment (P<0.05), but only the concentrations of IgA and IgM in the control group were significantly higher than those in
the observation group after treatment (P<0.05). The incidence of adverse reactions in the observation group was significantly lower than that in the control group. Conclusion: Granulocyte colony-stimulating factor combined with erythropoietin can effectively correct anemia, improve nutritional
status and improve immune function in patients with chronic myelogenous leukemia.
Aplikasi Perancang Abstraksi Verilog Mesin Keadaan Terbatas Otomatis
Authors: Azmi Fairuz
Published: December 2021

Saat ini, hampir semua perangkat elektronik menggunakan prosesor di dalamnya. Dalam sebuah prosesor, terdapat bagian control unit yang berfungsi mengatur operasi dari komponen-komponen di dalam prosesor. Control unit merupakan sebuah mesin keadaan terbatas atau disebut finite state machine (FSM). Rangkaian FSM dapat disintesis secara manual ataupun secara otomatis menggunakan bahasa abstraksi Verilog. Dalam penelitian ini, dibuat sebuah aplikasi yang dapat membantu pengguna merancang FSM dan selanjutnya menyimpannya dalam format Verilog. Aplikasi yang dibuat secara fungsional dapat berjalan dengan kesesuaian 100% dan mampu untuk membuat rancangan Verilog untuk FSM dengan berbagai model dan teknik pengkodean state. Simulasi modul Verilog yang dihasilkan juga sesuai dengan spesifikasi rangkaian FSM yang dirancang.
Clinico-pathological correlation of linear dermatoses along the lines of Blaschko: An observational study
Authors: Pise Gajanan A , Dastikop Shilpa V , S Manjunath , Manohar Naveen , Patil Malteshgauda N
Published: December 2021

Several epidemiological studies have described linear dermatoses; however, only few studies have correlated linear dermatoses along Blaschko’s lines with the histopathological findings. The aims of this study were to investigate the clinical patterns of various linear dermatological lesions along Blaschko’s lines and investigate the correlations between these dermatological lesions and their histopathological features.

Patients who attended our dermatology out-patient department with linear dermatoses along the Blaschko’s lines were included in the study. Detailed history was obtained, clinical examination was performed, and a final provisional clinical diagnosis was noted. Subsequently, biopsy of the lesions was performed for histopathological examination. Of 62 patients who presented with linear lesions along the Blaschko’s lines, 45 patients underwent biopsy and histopathological examination.

Of 45 patients who underwent biopsy, clinico-pathological correlation was observed in 100% of those diagnosed with lichen striatus and linear morphea, 89% of those diagnosed with hypomelanosis of Ito, 80% of those diagnosed with linear epidermal nevus, 75% of those diagnosed with lichen planus, and 67% of those diagnosed with nevus depigmentosus.

The importance of correlation of linear lesions with their histopathological features in dermatology cannot be over emphasized. However, 100% correlation may be wishful thinking, and a correlation can help choose the appropriate line of management. Our results highlight this discrepancy and add to the knowledge on linear dermatosis.
Capillaroscopic nail fold changes in collagen vascular diseases: A prospective observational study from a tertiary care teaching hospital in Western India
Authors: Shukla Ratnakar , Kapoor Sheena , Patil Sharmila , Patil Anant
Published: December 2021

: To examine nail changes with capillaroscopy in patients with collagen vascular diseases.

In this prospective observational study, patients with collagen vascular diseases presented to dermatology outpatient department of a tertiary care center were subjected to capillaroscopy. Structural and morphological abnormalities in these patients were noted.

Fifty patients (Mean age 38.2 years; 86% females) with mean disease duration of 1.96 years were included. Patients with systemic sclerosis and systemic lupus erythematosus constituted 34% and 32% patients respectively. Twenty two (44%) patients had presence of dilated nail fold capillary loops. Out of 17 patients with systemic sclerosis, 15(88.23%) and 14(87.5%) showed dilated nail fold capillary loops and capillary drop-pouts respectively. Capillary dropouts were observed in 14(82.35%) patients. Raynaud’s phenomenon, splinter hemorrhage and fingertip scarring was observed in 11(64.71%), six (35.29%) and 33(17.65%) patients respectively. Ragged cuticle was observed in four (25%) patients with systemic lupus erythematosus.

In our study, systemic sclerosis and systemic lupus erythematosus were two most common disorders. Dilated nail fold capillary loops/giant capillaries were the most common observation in overall population. Dilated nail fold capillary loops, capillary dropouts, Raynaud’s phenomenon, splinter hemorrhage and fingertip scarring were common in patients with systemic sclerosis.
Analisis Sidik Jari Kromatografi Lapis Tipis Tanaman Anting-Anting (Acalypha indica L.)
Authors: Laksono Muhammad Teguh , Hayati Elok Kamilah
Published: December 2021

Anting-anting plant (Acalypha indica L.) is a plant that the community has used as raw material for herbal medicine. Anting-anting plants contain chemical compounds, so it is difficult to ensure these plants' safety and quality control. The research objective was to validate the method by knowing the stability, specificity, precision, and rigidity of the chromatographic profile of alkaloid compounds in the TLC analysis of the anting-anting extract. Extraction was carried out using ethyl acetate solvent for 20 minutes with a frequency of 42 kHz. The eluent used is cyclohexane: toluene: diethylamine (75:15:10) with Dragendorff reagent. The method of validation was acceptable according to the criteria except for the stability test of the analyte during chromatography. The instability of the analyte is indicated that not all spots form a straight diagonal line. The specificity of the method was carried out by comparing the fingerprint patterns of the leaves of the anting-anting with ekor kucing (Acalypha hibsida Farm.) and teh-tehan plants (Acalypha siamensis). The fingerprint profile showed a yellow stain (Rf = 0.39) on the leaves of the anting-anting, which did not appear in the fingerprint profiles of the two comparison samples. Keywords: anting-anting, fingerprint analysis, thin layer chromatography, method validation Anting-anting (Acalypha indica L.) merupakan tanaman yang telah dimanfaatkan masyarakat sebagai bahan baku obat herbal. Anting-anting mengandung banyak senyawa kimia sehingga sulit menjamin keamanan dan pengendalian mutu dari tanaman tersebut. Penelitian ini dilakukan untuk validasi metode dengan mengetahui kestabilan, spesifitas, presisi, dan ketegaran profil kromatografi senyawa alkaloid pada analisis KLT ekstrak anting-anting. Ekstraksi dilakukan menggunakan pelarut etil asetat selama 20 menit dengan frekuensi 42 kHz. Eluen yang digunakan adalah sikloheksana : toluena : dietilamin (75:15:10) dengan reagen Dragendorff. Validasi metode dapat diterima sesuai kriteria kecuali uji stabilitas analit selama kromatografi. Ketidakstabilan analit ditunjukkan dengan seluruh noda yang dihasilkan tidak membentuk garis diagonal yang lurus. Spesifitas pada metode dilakukan dengan membandingkan pola sidik jari daun anting-anting dengan daun ekor kucing (Acalypha hibsida Farm) dan daun teh-tehan (Acalypha siamensis). Profil sidik jari menunjukkan bahwa terdapat noda berwarna kuning kehijauan (Rf = 0,39) pada daun anting-anting yang tidak muncul pada profil sidik jari kedua sampel pembanding tersebut. Kata kunci: anting-anting, analisis sidik jari, kromatografi lapis tipis, validasi metode
To live but Die Inside: A Lamentable State of Montressor in “The Cask of Amontillado”
Authors: C. Francisco Jesusa
Published: December 2021

The enduring quality of "The Cask of Amontillado" makes it a timeless classic in which researchers from different generations offer a variety of subjective interpretations. This study aims to look closer to the story of "The Cask of Amontillado" to reveal other underlying themes. The themes were identified using content/textual analysis and a humanistic literary approach in interpreting meanings. The themes discovered involve excessive self-esteem, a penchant for prestige, lusting for another's good fortune (envy), and love deprivation. These themes, in a way, express the psychological needs of humans reflected in Maslow's Hierarchy of Needs. Left unsatisfied, these basic human needs (self-esteem, prestige, and love) led to the characters' downfall because their thoughts and actions were inconsistent with ethical conduct. Findings of the study may add to the existing interpretations of the story, which primarily discuss and look into the various facets of its overarching theme of revenge along with Montressor’s mental condition.
‘Tilik’: A Study of Power Among Javanese Women Through Gossip
Authors: Kinasih Putri Rindu
Published: December 2021

Gossip plays a crucial part in our communicative and social behavior as it is thought to be a manifestation of any ‘ordinary’ everyday life. Interestingly, the portrayal of gossip in Javanese culture can be found in the recent viral short movie Tilik (The Ladies on Top). Unfortunately, contemporary interpretations and discussions about Bu Tejo often focus only on what gossip is about and its negative effect on the image of women. None of them observed the relation between gossip and power. Thus, the study aims to analyze gossip in Tilik movie by using the concept of power among Javanese women. The writer used the qualitative method. The writer focused on the theory of gossip and power; and used the concept of power among Javanese women proposed by Handayani and Novianto. This research revealed that gossip in Tilik becomes the weapon of choice in the female arsenal due to the rivalry between Bu Tejo and Dian. Bu Tejo’s negative attitude towards Dian can be seen as a political tactic for Javanese women, and the personal is political. Lastly, the acts of gossiping in the movie match with the concept of how Javanese women play the game of power through ­srawung (socialization).
La paz del vacío y la bola de la Revolución: aproximaciones a El samurái de la Graflex
Authors:   Universidad Nacional Autónoma de México, Centro Regional de Investigaciones Multidisciplinarias, Mexico, Saldaña Moncada David Issai
Published: December 2021

This paper deals with El samurái de la Graflex, by Daniel Salinas Basave. The analysis focuses on the representation of a historical character of Japanese origin: Kingo Nonaka, whose figure represents the irruption of a culture that contrasts with the attitudes and ideosyncrasy of revolutionary Mexico. Nonaka concentrates elements that form the image of a Japan in transition towards modernity. Between meditation as a method for diving and fluency with a camera, Salinas Basave follows Nonaka in his wanderings and allows the reader to appreciate details of the history of the first half of the twentieth century from a perspective “alien” to the Mexican one, while building a space for reflection on writing and memory.
Emulación pictórica y experiencia ilusoria: pictorialismo en El biombo y los frutos de Jesús Gardea
Authors:   Universidad Autónoma Metropolitana-Azcapotzalco, Mexico, Samperio Jiménez Daniel
Published: December 2021

Belonging to the last stage of Jesús Gardea, El biombo y los frutos is one of his most enigmatic and perplexing novels. This article examines the relationship with painting in this work under the notion of pictorialism as a textual phenomenon that creates pictorial effects in the narrative. In particular, the dialogue between painting and gaze is analyzed, where the narration plays with both the vivid and illusory experience of representation in the story. With this, it sets out to elucidate one of the most suggestive elements of Gardea’s writing, especially manifested in this novel, not without seeking to contribute to a greater understanding of the author’s latest creative stage and aesthetic proposal.
Cuerpos abiertos, cuerpos insaciables. Modelos narratológicos y una vieja maldición en El Sinaloa, de Guillermo Rubio y de Vizcarrondo
Authors:   Universidad Autónoma de la Ciudad de México, Mexico, Vilchis Fraustro José Carlos
Published: December 2021

Luis Manuel Salcido Arispuro, whose alias gives its name to the novel El Sinaloa, is a policeman with a dual personality: an agent in the service of the Mexican State, which in turn serves the interests of the Sinaloa drug cartel mafia of the late 1990s. Hand in hand with Guillermo Rubio’s narrative, the reader will be introduced to the world of the mafia, with its impunity and self-confidence, where amid parties, excesses and violence, we will discover a charismatic character, with an insatiable hunger and of an exacerbated voracity. Given this, it is valid to ask ourselves if it is a normal condition of a character of its type, or if it is a curse of unsuspected, as well as ancestral dyes.
Reflexiones sobre la escritura cinematográfica en México: Apuntes para una historia (1965-2013)
Authors:   Universidad Nacional Autónoma de México, Instituto de Investigaciones Filológicas, Mexico, Sheinbaum Lerner Diego
Published: December 2021

The reflections on screenwriting in Mexico constitute a tradition that has not been critically reviewed. This article recovers fundamental texts of Mexican writers and teachers in order to analyze their attempts to articulate this practice. The texts oscillate between the poetics, the essay and the didactic manual. A stimulating dialogue arises from interweaving their ideas about the nature of the screenplay, its narrative and dramatic dimensions, the specificity of this type of writing and the creative process. The review begins with El conocimiento cinematográfico y sus problemas (1965), written by José Revueltas and ends with the unpublished book by Beatriz Novaro, El roce de los lenguajes (2013).
O mundo natural da Idade Média: aproximações conceituais
Authors:   Universidade Federal de Goiás, Brazil, Louzada Fonseca Pedro Carlos
Published: December 2021

Este artículo se centra en un comprensivo análisis crítico-interpretativo del complejo concepto de naturaleza cultivado durante el devenir de los siglos medievales. Investiga los diferentes matices de este concepto dentro de sus diversas condicionantes socioculturales. Principalmente en el terreno religioso letrado, el estudio desarrolla un abordaje representativo y comparatista de los principales pensadores de la Antigüedad Clásica que influenciaron directa o indirectamente en la política ideológica de tradición judeocristiana (dominante en el pensamiento cultural de la Edad Media sobre la naturaleza). El artículo hace un fuerte enfoque social en su contemporaneidad temática.