bluuebunny/crossref_metadata_2025 huggingface dataset:
EFEITOS DA EXTRAÇÃO VERDE ASSISTIDA POR ULTRASSOM COMO PRÉ-TRATAMENTO NA OBTENÇÃO DO ÓLEO ESSENCIAL E HIDROLATO DE AROEIRA VERMELHA (Schinus terebinthifolius RADDI)
Authors: Oliveira Fabricia Alessandra Garcia Mello de , Bueno Carla Cristina , Dyna Fabíola Adriana Garcia Mello , Lembi Michelle Karine dos Santos , Silva Thainá Aparecida Rafael , Silva Creir Da , Moritz Cristiane Mengue Feniman , Sakai Otávio Akira
Published: February 2022

A aroeira vermelha, conhecida como pimenta rosa, natural de alguns estados do Brasil, é uma planta medicinal que apresenta atividades biológicas como anti-inflamatório, antipirético e analgésico. O objetivo do estudo foi verificar a influência do pré-tratamento por ultrassom no rendimento da extração do óleo essencial e hidrolato. A extração do óleo essencial foi realizada pelo método Clevenger com pré-tratamento de ultrassom com 30, 50 e 70% de potência. Observou-se que na potência de 70% obteve um maior rendimento. Em relação ao hidrolato, não se teve diferença significativa na extração sem e com o tratamento do ultrassom. Também foi realizada a caracterização por meio da espectroscopia do infravermelho por transformada de Fourier – reflectância total atenuada (FTIR-ATR), sendo uma técnica de enorme aplicabilidade para diversos tipos de amostras. É visto que o método da extração verde tem contribuído amplamente na redução de resíduos e na inovação de técnicas mais sustentáveis.
INFLUÊNCIA DA ADIÇÃO DE GOMA DE ALFARROBA NAS PROPRIEDADES DE FILMES À BASE DE PROTEÍNA DE SOJA
Authors: Medeiros Kayque Antonio Santos , Amado Laís Ravazzi , Silva Keila De Souza
Published: February 2022

A proteína de soja é o mais importante representante da proteína de leguminosa e tem apresentado alto potencial para a fabricação de filmes. As misturas entre proteínas e polissacarídeos podem melhorar o desempenho, estabilidade, funcionalidade e resistência de filmes de biopolímero em comparação com filmes simples. Este trabalho tem como objetivo desenvolver filmes compostos com isolado protéico de soja (SPI) e concentrado protéico de soja (SPC) e diferentes concentrações de goma de alfarroba (LBG), bem como, avaliar o efeito da adição de polissacarídeo nas propriedades óticas e mecânicas. barreira, cor, microestrutura, solubilidade e umidade dos filmes SPI e SPC. Para tanto, foram elaborados filmes compostos variando a concentração de LBG (0; 0,05; 0,1; 0,2; 0,3; 0,4%) e fixando a concentração de SPI e SPC (5%) em solução. O glicerol foi utilizado em todas as formulações como plastificante. Foram avaliadas a microestrutura, solubilidade, umidade, permeabilidade ao vapor de água, propriedades ópticas e mecânicas dos filmes simples e compostos. A solubilidade e barreira do filme à luz foram aumentadas em filmes SPI com adição de LBG, mas não foram alteradas em filmes SPC com adição de goma.Todos os filmes compostos apresentaram valores de resistência à tração mais elevados do que os filmes simples. A leveza dos filmes compostos foi menor do que os filmes simples, porém a barreira de vapor de água foi semelhante.
Diffamation, dénigrement, procédure bâillon ?
Authors: Raffray Ronan
Published: February 2022

Consécutivement à cette décision, la justice a parfois été accusée dans la presse d’avoir fait droit à une demande dite « bâillon », protectrice des intérêts de la filière, représentée à l’instance par le Conseil interprofessionnel du vin de bordeaux (CIVB). Il est donc nécessaire et instructif d’observer le détail de la motivation de ce jugement du tribunal de Libourne, largement diffusé, en situant cette affaire dans le contexte environnemental propre au vignoble bordelais, de sorte que chacun puisse s’appuyer sur des éléments tangibles pour forger son opinion.
Comprehensive characterization of CRC with germline mutations reveals a distinct somatic mutational landscape and elevated cancer risk in the Chinese population
Authors: Yao Jianfei , Zhen Yunhuan , Fan Jing , Gong Yuan , Ye Yumeng , Guo Shaohua , Liu Hongyi , Li Xiaoyun , Li Guosheng , Yang Pan , Wang Xiaohui , Liu Danni , Huang Tanxiao , Cao Huiya , Suo Peisu , Li Yuemin , Yu Jingbo , Song Lele
Published: February 2022

Objective: Hereditary colorectal cancer (CRC) accounts for approximately 5%–10% of all CRC cases. The full profile of CRC-related germline mutations and the corresponding somatic mutational profile have not been fully determined in the Chinese population. Methods: We performed the first population study investigating the germline mutation status in more than 1,000 (n = 1,923) Chinese patients with CRC and examined their relationship with the somatic mutational landscape. Germline alterations were examined with a 58-gene next-generation sequencing panel, and somatic alterations were examined with a 605-gene panel. Results: A total of 92 pathogenic (P) mutations were identified in 85 patients, and 81 likely pathogenic (LP) germline mutations were identified in 62 patients, accounting for 7.6% (147/1,923) of all patients. MSH2 and APC was the most mutated gene in the Lynch syndrome and non-Lynch syndrome groups, respectively. Patients with P/LP mutations had a significantly higher ratio of microsatellite instability, highly deficient mismatch repair, family history of CRC, and lower age. The somatic mutational landscape revealed a significantly higher mutational frequency in the P group and a trend toward higher copy number variations in the non-P group. The Lynch syndrome group had a significantly higher mutational frequency and tumor mutational burden than the non-Lynch syndrome group. Clustering analysis revealed that the Notch signaling pathway was uniquely clustered in the Lynch syndrome group, and the MAPK and cAMP signaling pathways were uniquely clustered in the non-Lynch syndrome group. Population risk analysis indicated that the overall odds ratio was 11.13 (95% CI: 8.289–15.44) for the P group and 20.68 (95% CI: 12.89–33.18) for the LP group. Conclusions: Distinct features were revealed in Chinese patients with CRC with germline mutations. The Notch signaling pathway was uniquely clustered in the Lynch syndrome group, and the MAPK and cAMP signaling pathways were uniquely clustered in the non-Lynch syndrome group. Patients with P/LP germline mutations exhibited higher CRC risk.
Information Dark Energy can resolve Hubble tension  and is falsifiable by experiment.
Authors: Gough Michael Paul
Published: February 2022

We consider the role information energy can play as a source of dark energy. Firstly, we note that, if stars and structure had not formed in the universe, elemental bits of information describing the attributes of particles would have exhibited properties similar to the cosmological constant. The Landauer equivalent energy of such elemental bits would be defined identical in form and value to the characteristic energy of the cosmological constant. But, with the formation of stars and structure, stellar heated gas and dust now provides the dominant contribution to information energy with the characteristics of a dynamic, transitional, dark energy. At low redshift, z<~1.35, this dark energy emulates the cosmological constant with a near constant energy density, w=−1.03±0.05, and an energy total similar to the mc2 of the universe's ∼1053 kg of baryons. At earlier times, z>~1.35, information energy was phantom, differing from the cosmological constant, Λ, by a CPL parameter difference of ∆wo=−0.03±0.05 and ∆wa=−0.79±0.08, values sufficient to account for the H0 Tension. Information dark energy agrees with most phenomena as well as Λ, while exhibiting characteristics that resolve many tensions and problems of ΛCDM: the cosmological constant problem; the cosmological coincidence problem; the H0 and σ8 tensions. As this proposed dark energy source is not usually considered, we identify the expected signature in H(a) that will enable the role of information dark energy to be falsified by experimental observation.
Integrated Analysis of microRNA-mRNA Network Predicts Potential Regulators of Atrial Fibrillation in Human
Authors: Wang Rong , Bektik Emre , Sakon Phraew , Wang Xiaowei , Huang Shanying , Meng Xiangbin , Chen Mo , Han Wenqiang , Chen Jie , Wang Yanhong , Zhong Jingquan
Published: February 2022

Atrial fibrillation (AF) is a form of sustained cardiac arrhythmia and microRNAs (miRs) play crucial roles in pathophysiology of AF. To identify novel miR-mRNA pairs, we performed RNAseq from atrial biopsies of AF and non-AF patients. Differentially expressed miRs (11-down and 9-up) and mRNAs (95-up and 82-down) were identified and hierarchically clustered in a heat-map. Subsequently, GO, KEGG, and GSEA analyses were run to identify deregulated pathways. Then, miR targets were predicted in miRDB database, and a regulatory network of negatively correlated miR-mRNA pairs was constructed using Cytoscape. To select potential candidate genes from GSEA analysis, top-50 enriched genes in GSEA were overlaid with predicted targets of differentially deregulated miRs. Besides, protein-protein-interaction (PPI) network of enriched genes in GSEA was constructed, and subsequently GO and canonical pathway analyses were run for genes in PPI network. Our analyses showed that TNF-α, p53, EMT, and SYDECAN1 signaling were among the highly affected pathways in AF samples. SDC-1 (syndecan-1) was the top-enriched gene in p53, EMT, and SYDECAN1 signaling. Consistently, SDC-1 mRNA and protein levels were significantly higher in atrial samples of AF patients. Among negatively correlated miRs, miR-302b-3p was experimentally validated to suppress SDC-1 transcript levels. Overall, our results suggested that miR-302b-3p/SDC-1 axis may involve in pathogenesis of AF.
Impact of Forest Fires in Sumatra and Kalimantan to Atmospheric Pollution During Period Of 2010-2015
Authors: Gusnita Dessy
Published: February 2022

contribute significantly. Pollutant emissions caused by forest fires comprising CO, SO2 and dust (PM10). This paper will be analyzed estimates of pollutant emissions in both Kalimantan and Sumatra using the estimation method based on the amount of material burned. Estimates of the emissions and dispersion of pollutants such as particulates, sulfur dioxide, carbon monoxide were investigated. Distribution and concentration of pollutants used time series of monthly data and spatial map based on satellite data. Extensive data from the 2010-2014 forest fires data from the ministry of the environment and forestry (KLHK) and forest fire data period 2015 from LAPAN. Pollutant concentration data used AIRS on satellite data, OMI satellite and MERRA during 2010-2011 and in 2014-2015, adjusted to the data in situ vast wildfires for both regions. The results of estimation of pollutant emissions in Sumatra shows emissions from forest fires for the period of 2010 greater than in 2011, reaching 9 tons of CO per year, while emissions from fires and plantations during 2011 were higher than in 2010 with a very high value of 150 Tons/year for pollutants CO. In Kalimantan, emissions from forest fires during 2010-2011 CO emissions highest in West Kalimantan 11.13 tons/year and South Kalimantan 12.14 tons of CO per year. Emissions from fires and plantations in South Kalimantan reached 32.11 tons/year.  
Nitrate Adsorption capacity of Activated Gamalama Volcanic Ash
Authors: Zam Zam Zulkifli , Limatahu Nur Asbirayani , Baturante Nur Jannah
Published: February 2022

The adsorption process of nitrate from an aqueous solution by using activated Gamalama volcanic ash was investigated. Gamalama volcanic ash (VA) was activated with HNO3 2M. The effect of adsorbent mass and initial nitrate concentration on nitrate adsorption were observed in this study. The adsorption process was conducted using a various mass of adsorbent (1 g, 2 g, 4 g, 6 g, and 8 g), various initial concentrations of nitrate (20 mg/L, 30 mg/L,40 mg/L, 50 mg/L, and 60 mg/L). The increasing of adsorbent mass decreased the adsorption capacity was observed. It was also found that the increase in initial concentration increased the adsorption capacity. The highest nitrate adsorption capacity showed by 1 gram adsorbent for 0.167 mg/g, and at nitrate initial concentration 80 mg/L, for 1.831 mg/g. Adsorption isotherm of nitrate on activated VA was determined and figured. These isotherms were modelled according to Freundlich and Langmuir adsorption isotherm.
Rash Model Approach for Analysis of Misconception on Chemistry Learning with Distractor Analysis
Authors: Mulyani Sri , Haniza Nur , Ramadhani Dimas Gilang , Mahardiani Lina
Published: February 2022

Multiple-choice questions can be used to identify misconceptions through distractor analysis. Distractor analysis for identifying misconceptions using Rasch modelling to find out how students choose options and whether they have any misconceptions. The test instrument uses questions from the teacher association in Indonesia to assess students’ ability to master chemical contexts. The number of question items used is 35 and has been validated and tested for reliability to be feasible to use. Questions were given to 462 first-year high school students. The fit item analysis results show that there are several questions related to clothing that indicate misconceptions. This is supported by the distractor analysis value, which found that misconceptions indicate questions related to electrolysis, the incidence of colligative properties in daily life and the factors that affect corrosion. The distractor’s value and the option probability curve are used to see how students know the ideas offered. The analysis results found that the material in the form of concepts and their application showed a large misconception, in which students would find it difficult to combine concepts and their applications.
El Sistema de Calificación Lineal de CAPRIGRAN Evidencia los Signos de Selección para la Aptitud Lechera en Cabras y Machos Cabríos de Raza Murciano-Granadina
Authors: Fernández Álvarez J. , León Jurado J.M. , Navas González F.J. , Iglesias Pastrana C. , Delgado Bermejo J.V.
Published: February 2022

La selección para la zoometría define la longevidad productiva, la resistencia, las capacidades productivas mejoradas de los individuos y, en consecuencia, su rentabilidad a largo plazo. Cuando el análisis zoométrico está dirigido a grandes poblaciones seleccionadas o en vías de selección, los sistemas de calificación lineal (LAS) brindan una respuesta oportuna. El análisis particular de cada variable permite determinar estrategias específicas para cada rasgo y servir de modelo para otras razas. Entre las estrategias propuestas la reducción/reajuste de los niveles en la escala como ocurre con los rasgos relacionados con las extremidades, la ampliación de la escala como ocurre en la estatura de los machos, o la subdivisión de la escala utilizada en los machos en dos categorías, machos menores de dos años y machos de dos años en adelante. Murciano-Granadina ha derivado hacia mejores rasgos morfológicos ligados a la aptitud lechera pero sin perder el fundamento de la base zoométrica que le confiere una mayor adaptabilidad al medio. Por lo tanto, tales estrategias pueden ayudar a lograr una mejor comprensión del impulso de selección de caracteres zoométricos ligados a la aptitud lechera en la población murciano-granadina y su evolución futura para mejorar la rentabilidad y eficiencia de los planes de mejora.
Typologie des systèmes d’élevage caprin en milieu rural au Bénin en vue d’une étude ultérieure de leur durabilité
Authors: Houessou S.O. , Vanvanhossou S.F.U. , Yassegoungbe F.P. , Adenile A.D. , Dahouda M. , Guimaraes V.P. , Dossa L.H.
Published: February 2022

Cette étude a été entreprise afin de caractériser la diversité des systèmes d’élevage caprin et identifier les principales contraintes et opportunités pour leur durabilité dans les différentes zones agro-écologiques du Bénin. Les données collectées sur 478 troupeaux caprins ruraux élevés dans quatre communes du Bénin ont été soumises à une analyse en composantes principales catégorielles et à l’algorithme de classification “two-step” du logiciel statistique IBM®-SPSS®. Quatre différents types d’élevages caprins ont été identifiés en utilisant le mode de logement pratiqué, le nombre de femelles reproductrices dans le troupeau et la disponibilité en ressources des producteurs comme variables discriminantes. La claustration saisonnière comprend l’attache des caprins au piquet (groupe 1, n = 203, 47%) ou la mise en enclos (groupe 4, n = 29, 5%) durant la journée pendant la saison des pluies. Dans le système de divagation totale, les caprins erraient toute l’année en de petits troupeaux (groupe 2, n = 222, 47%) ou de grands troupeaux (groupe 3, n = 24, 5%). La relation entre les caractéristiques socio-économiques des agriculteurs, les contraintes du milieu et les pratiques de gestion dans chaque type d’exploitation met en évidence l’impact du faible investissement des producteurs, du manque de ressources alimentaires, d’accès à l’éducation et à la formation principalement par les femmes sur la mauvaise gestion des élevages de caprins. En outre, une meilleure gestion du logement et de l’alimentation des caprins ainsi que le développement de marchés de caprins sont essentiels pour le développement de l’élevage caprin villageois.
Havayolu Sektörü Çalışanları Bakış Açısından Havalimanlarının Çok Kriterli Karar Verme Yöntemleriyle Değerlendirilmesi
Authors: ÖZDAĞOĞLU Aşkın , IŞILDAK Barış , KELEŞ Murat Kemal
Published: February 2022

Havalimanlarında verilen hizmetler, havalimanlarının fiziksel ve çevresel yapıları, coğrafi konumları gerek yolcular açısından gerekse de havayolu sektörü çalışanları açısından oldukça önemlidir. Bu çalışmada Batı Akdeniz ve Ege Bölgesinde faaliyet gösteren birbirine yakın üç havalimanının karşılaştırmalı analizi yapılmıştır. Çalışma kapsamındaki havalimanları, havalimanı yer hizmetleri ekibi ve uçuş mürettebatı olmak üzere iki farklı havayolu çalışan ekibi gözüyle değerlendirilmiştir. Çalışmada yapılan analizlerde çok kriterli karar verme yöntemleri kullanılmıştır. Değerlendirme kriterlerinin ağırlığı Bulanık SWARA ile bulunmuş, üç havalimanının sıralamaları da COPRAS ve SAW yöntemleriyle ayrı ayrı yapılmıştır. Çalışma sonucunda havalimanı yer hizmetleri ekibi ve uçuş ekibi görüşlerine göre her iki çok kriterli karar verme yöntemi kullanılarak yapılan analiz sonuçları karşılaştırılmıştır. Analiz sonuçlarına göre; en önemli üç kriter sırayla, “pist uzunluğu”, “taksirutlar” ve “yükseklik-rakım”, en önemsiz kriterin ise “terminal alanı büyüklüğü” olduğu tespit edilmiştir. Havalimanı yer hizmetleri ekibi ve uçuş ekibi görüşlerine göre kriter sıralamaları aynı olmasına rağmen, kriterlerin önem dereceleri ve havalimanlarının sıralamalarının farklı çıktığı görülmüştür. Bunun nedeni, havalimanlarında çalışan yer hizmetleri personeli ile uçuş ekibi personelinin yaptıkları işler ve görev tanımları farklı olduğu için havalimanından beklentilerine bağlı olarak değerlendirme kriterlerinin önem dereceleri de farklılık arz etmiştir. Çalışmanın havalimanları yöneticilerine, havayolu sektörü çalışanlarına ve havalimanlarını kullanan yolculara faydalı olacağı düşünülmektedir.
Türkiye İçin Uluslararası Sağlık Turizmi Talebinin Kantitatif Çerçevede Değerlendirilmesi
Authors: ÖZTÜRK Yunus Emre , ÖZCAN Mehmet
Published: February 2022

Sağlık Turizmi kavramı, turizm araştırmaları literatüründe önemli bir konu olarak gündeme gelmektedir. Sağlık turizmi insanların tedavi amacıyla yaşadıkları bölge dışında bir yere seyahatlerini içerir. Sağlık turizmi sağlık amaçlı uluslararası hareketlilik potansiyelini kullanarak sağlık kurumlarının gelişmesine ve büyümesine imkân veren bir sektördür. Doğal imkânlarından ve göreli düşük seyahat maliyetlerinden ötürü Türkiye küresel sağlık turizmi pazarında önemli bir oyuncu olabilir. Bu nedenle son yıllarda çeşitli kurumlar Türkiye’nin sağlık turizmi potansiyelini araştırmaya başlamıştır. Bu çabalara katkı sağlamak amacı ile çalışma Türkiye’ye yönelen sağlık turizmi talebini ampirik olarak modellemeye odaklanmıştır. Çalışmanın amacına ulaşmak için üç adet model kurulmuş ve tahmin edilmiştir. Sonuçlar iki önemli hususa dikkat çekmektedir. Öncelikle Türkiye’nin sağlık turizmi için kullanılabilir verileri yetersiz ve zayıftır. İkinci önemli sonuç olarak, sağlık turistlerinin geçmiş ziyaretlerden edindiği tecrübe ve deneyimin Türkiye’nin sağlık turizmi ziyaretçi sayısı üzerindeki etkisinin zayıf olduğu bulunmuştur.
PERAN WAKAF UANG DALAM MEMBERDAYAKAN PENDIDIKAN
Authors: Syamsuri Syamsuri , Al Mananaanu Yusuf
Published: February 2022

Tujuan penelitian ini untuk mengetahui peran wakaf uang dalam memberdayakan pendidikan yang sudah teralisasikan di beberapa lembaga wakaf. Hasil penelitian menunjukkan bahwa peran wakaf uang sangat penting dalam memberdayakan pendidikan. Wakaf uang memberi peran terhadap beberapa lembaga wakaf dalam mendukung dan meningkatkan pendidikan secara materil. Peneliti memilih wakaf uang karena perlunya pendayagunaan wakaf uang yang memberi implikasi pada perkembangan pendidikan serta kurangnya sosialisasi pada masyarakat terhadap wakaf uang di Indonesia. Di sisi lain, peneliti ingin mendapat gambaran potensi wakaf uang dan gambaran strategi dalam upaya pengembangan ekonomi umat khususnya dalam bidang pendidikan. Metode yang digunakan dalam penelitian ini adalah metode kualitatif dengan pendekatan analisis deskriptif untuk menjelaskan pelaksanaan wakaf uang dalam memberdayakan pendidikan. Ruang lingkup kegiatan penelitian, keterpaduan terbatas pada Lembaga Wakaf yang memaksimalkan wakaf uang dalam memberdayakan pendidikan di Indonesia, serta bagaimana menyusun model pemberdayaan wakaf uang tunai yang bersinergi dalam bidang pendidikan oleh lembaga wakaf. Selain itu juga untuk mendapatkan penelitian lebih mendalam tentang wakaf uang dan juga mengoptimalkan ke bidang lainnya guna memberdayakan umat. [The purpose of this study was to determine the role of cash waqf in empowering education that has been realized in several waqf institutions. The results showed that the role of cash waqf is very important in empowering education. It gives a role to several waqf institutions in supporting and improving education. Researchers chose cash waqf to utilize cash waqf which implicate the development of education when there is a lack of socialization of it in the community in Indonesia. On the other hand, the researcher wants to get an overview of the potential of cash waqf and a description of the strategy to develop the economy, especially in education. The method used in this research is a qualitative method with a descriptive analysis approach to explaining the implementation of cash waqf in empowering education. The scope of the research was limited on the integration of waqf institutions that maximize cash waqf in empowering education in Indonesia, as well as how to develop a model for empowering cash waqf that synergizes in education by waqf institutions. Also to get more in-depth research on cash waqf and optimize it into other fields to empower people.]
SPIN OFF PERBANKAN SYARIAH DI INDONESIA: PROYEKSI PERHITUNGAN DAN STUDI KRITIS PERATURAN
Authors: Pratiwi Angrum , Rizal Fitra , Mainata Dedy
Published: February 2022

Undang-undang Perbankan Syariah No. 21 Tahun 2008 menyebutkan bagi Bank Umum Konvensional (BUK) yang memiliki Unit Usaha Syariah (UUS) dengan nilai aset telah mencapai paling sedikit 50% dari total nilai aset bank induknya atau 15 (lima belas) tahun sejak berlakunya Undang-undang wajib menjadi Bank Umum Syariah (BUS). Dalam Roadmap Pengembangan Perbankan Syariah Tahun 2020-2025 terkait Perizinan, Pengaturan dan Pengawasan, OJK tidak menjelaskan kesiapan UUS untuk spin off dari Bank Induk Konvensional menjadi BUS. Penelitian ini bertujuan mengkritisi kebijakan pemerintah terkait perubahan UUS menjadi BUS, serta memberi masukan untuk merevisi Undang-undang Perbankan Syariah terkait perubahan UUS menjadi BUS. Penelitian ini menggunakan metodologi penelitian kuantitatif dengan pendekatan deskriptif. Hasil Penelitian menunjukkan bahwa Unit Usaha Syariah (UUS) bisa berubah menjadi Bank Umum Syariah (BUS) pada tahun 2034 bukan pada tahun 2023. Peraturan dan regulasi terkait teknis operasional persiapan transmisi pemisahan UUS menjadi BUS, perlu diperkuat kembali dan dipertegas dengan peraturan yang baru. [Sharia Banking Law No. 21 of 2008 states that Conventional Commercial Banks (BUK) that have Sharia Business Units (UUS) with asset values have reached at least 50% of the total asset value of their parent bank or 15 (fifteen) years since the enactment of the Law are obliged to become Commercial Banks. Sharia (BUS). In the 2020-2025 Sharia Banking Development Roadmap related to Licensing, Regulation and Supervision, OJK did not explain the readiness of UUS to spin off from a Conventional Parent Bank to become a BUS. This study aims to criticize government policies regarding the change of UUS to BUS, as well as to provide input for revising the Sharia Banking Law regarding the change from UUS to BUS. This research is a quantitative research with a descriptive approach. The results showed that the Sharia Business Unit (UUS) could turn into a Sharia Commercial Bank (BUS) in 2034 instead of 2023. Regulations and regulations related to the technical operational preparation for the transmission of separation of UUS into BUS, need to be strengthened and reinforced with new regulations.]
THE RELATIONS OF SOCIAL ACTION AND RELIGIOUS DISCOURSES IN THE PHENOMENON OF TOLAK BALA "DISASTER PREVENTION" OF COVID-19 IN TINGGIRAN VILLAGE, BATOLA
Authors: Saputra Riza
Published: February 2022

Artikel ini membahas fenomena kegiatan pencegahan bencana atau “tolak bala” Covid-19 yang dilakukan oleh masyarakat Desa Tinggiran Baru, Barito Kuala. Kegiatan ini diasumsikan oleh masyarakat sekitar dapat menghentikan dan menangkal virus Corona. Namun, hasil sebenarnya yang diperoleh dari kegiatan ini masih belum pasti. Oleh karena itu, menarik untuk mengetahui mengapa masyarakat di Desa Tinggiran melakukan ritual tolak bala untuk mencegah bencana covid-19. Untuk menjawab pertanyaan ini, kami menggunakan teori tindakan sosial yang disandingkan dengan wacana keagamaan dalam pandangan Max Weber dan mengumpulkan data dengan observasi, wawancara, dan dokumentasi. Dengan menggunakan metode kualitatif dan pendekatan fenomenologi, hasil penelitian ini mengarah pada beberapa poin: Pertama, peran narasi sejarah-tradisional, pandangan masyarakat desa terhadap kegiatan tolak bala terbentuk dari peristiwa sejarah yang berurutan bahwa tolak bala adalah hal yang biasa. aktivitas dan selalu menjadi alternatif untuk menghadapi situasi tersebut. Kedua, peran emosional-afeksi, dalam kegiatan tolak bala emosi merupakan salah satu faktor penentu yang mendukung keinginan masyarakat untuk melakukan kegiatan ini, Ketiga, peran tokoh agama dan kharismanya dalam struktur sosial desa Tinggiran Baru telah memperkuat narasi keagamaan dan mendorong masyarakat untuk mematuhi seruan kegiatan tolak bala. [This study discusses the phenomenon of disaster prevention activity or "tolak bala" of Covid-19 practiced by the villagers of Tinggiran Baru, Barito Kuala. The local people assume this activity can stop and ward off Coronavirus. However, the actual result obtained from this activity is still uncertain. Thus, it is exciting to know why people in Tinggiran village practice a tolak bala to prevent the covid-19 disaster. We use social action theory juxtaposed with religious discourse in Max Weber's view and collect the data with observation, interview, and documentation to answer this question. The results of this study lead to several points: First, the role of traditional-historical narrative, the view of villagers on tolak bala activity formed by the successive historical events that tolak bala is a common activity always becomes an alternative to deal with such situation. Second, the role of emotional-affectional in tolak bala activity is one of the determining factors that support the community's desire to do this activity. Third, the role of religious leaders and their charisma in the social structure of the village Tinggiran Baru has strengthened the sacred narrative and encouraged people to obey the call of tolak bala activity.]
Sex-Specific Association of Body Mass Index And Fatty Liver Index With Prevalence of Renal Hyperfiltration: A Cross Sectional Study Using Japanese Health Check-Up Data
Authors: Kitazawa Atsushi , Fukuda Yoshiharu
Published: February 2022

Background: The relationship between obesity and nonalcoholic fatty liver disease and renal hyperfiltration is controversial. This study aimed to assess the correlations of body mass index and fatty liver index, respectively, with renal hyperfiltration in non-diabetic subjects, considering age, sex, and body surface area.Methods: This cross-sectional study assessed the Japanese health check-up data (FY2018) of 62,379 non-diabetic individuals from a health insurance database. Renal hyperfiltration is the ≥95th percentile of estimated glomerular filtration rate (derived by Chronic Kidney Disease Epidemiology Collaboration formula) by gender and age in healthy subjects. After adjusting for potential confounders, multiple logistic regression models were applied to evaluate the correlation of renal hyperfiltration with body mass index categories and fatty liver index (10 equal parts).Results: A negative and positive correlation, respectively, were noted when the body mass index was<21 and ≥30 in women; however, a positive correlation was noted for BMI <18.5 and ≥30 in men. Renal hyperfiltration prevalence increased when fatty liver index increased for both sexes; the cutoff value for fatty liver index was 14.7 for women and 30.4 for men.Conclusions: Body mass index and renal hyperfiltration correlated linearly in women; however, in men, the correlation was U-shaped; therefore, differing by sex. However, fatty liver index correlated linearly with renal hyperfiltration in both sexes. Non-alcoholic fatty liver disease might be associated with renal hyperfiltration; Fatty liver index is a simple marker that can be obtained from health check-ups. Since a high fatty liver index correlated with renal hyperfiltration, it may be beneficial to monitor the renal function in such a population.
Saliva Tgfβ1 Level in Patients with Type 2 Diabetes Mellitus and Primary Hypertension on Dental Caries
Authors: - Masriadi , Idrus Hasta Handayani , Anas Risnayanti , Wijaya Muhammad Fajrin , Aldilawati Sari , Umniyati Helwiah , Alawiyah Tuti , Tasyah Nur Najma
Published: February 2022

Background: The purpose of this study is to analyze the relationship and differences in salivary Tgfβ1 levels in patients with type 2 diabetes mellitus (T2DM) and primary hypertension (PH) with dental caries patients.Methods: The research design used is a clinical experimental approach. Salivary examination of T2DM and PH patients was carried out by laboratory staff at the Matakali Health Center and assisted by the research team, then continued with the examination of TGFβ1 levels at the microbiology laboratory of Hasanuddin University, Indonesia, which became a research partner. Saliva TGFβ1 levels were measured with a commercial Human TGFβ1 kit ELISA Assaygenie. Sampling using purposive sampling technique. Test analysis with Chi Square and independent sample T-test. The sample size in this study was 60 samples, namely 30 T2DM patients, 30 PH patients aged 18-40 years. Analysis is Chi Square and independent T-test. Results: The results of this study when viewed from the distribution of tooth brushing habits in T2DM patients, namely the frequency of brushing teeth is not good (1x a day) and dental caries is 56.7%, while PH patients are 63.4%. This shows that the frequency of tooth brushing affects the occurrence of dental caries in T2DM and PH patients. Likewise, when viewed from the sex distribution of TD2M in males 60% and females the lowest 40%. Gender distribution in patients with PH & dental caries with the largest proportion of male 53.3% and the lowest female 46.7%. Salivary TGFβ1 levels of patients with T2DM & Caries, PH with dental caries were 577.85 pg/ml (0.042) and 386.3894 pg/ml (0.024). Then continued with testing the effect of TGFβ1 on T2DM and PH patients with dental caries, namely T2DM patients (p. 0.042) and PH patients (p. 0.024). This shows that there is a significant effect between salivary TGFβ1 levels of T2DM and PH patients on dental caries. Likewise, it was found that there was a significant difference between T2DM and PH in dental caries by looking at the average value of salivary TGFβ1 on PH was 386,3894pg/mL while salivary TGFβ1 on T2D was 577,8546pg/mL. It can also be seen from the standard deviation value of T2DM deviation is 173.04621, while HTP is 95.93092.Conclusion: There is associated and difference of Salivary TGFβ1 levels of patients with T2DM and PH at the age of 18-40 years with dental caries. The higher the salivary TGFβ1 level, the higher the risk of dental caries.
Development of a Deep Learning Technique to Analyze Air Quality from Social Media Response
Authors: Kumbalaparambil Thushara Sudheish , Menon Ratish , Radhakrishnan Vishnu P , Nair Vinod P
Published: February 2022

One of the prominent new-age methods used by today’s population in spreading awareness or drawing attention on an issue or concern is through social media platforms. In this study, the responses of general public to air quality that they share on a popular social media platform – Twitter, was taken as a virtual quantity that helps in measuring and analyzing the prevalent air quality. Machine learning technique based on self attention network was used to sort, clean and classify large amount of air pollution related Twitter responses extracted during 2019-2020 at Delhi in India. The temporal correlation of tweet response volumes with the ground monitored concentrations of air pollution and word cloud analysis were used to analyze the attitude of the public towards urban air quality. These analyses lead to the development of an air quality prediction model using ‘spaCy’ – similarity analysis method which attempts to predict the ground concentration range of pollutant PM2.5 from tweets received on a particular day.
WITHDRAWN: Determination of Trabecular Bone Changes in Smokers Using Fractal Analysis: A Case-Control Study
Authors: Azman Duygu , Tassoker Melek
Published: February 2022

Objectives
Fractal analysis is a mathematical method that enables to assess irregular and complex body structures expressed by fractal dimension (FD). Detection of the changes was aimed on trabecular structure of the mandibles in smoker individuals through fractal analysis method via digital panoramic images.
Study design:
The fractal analysis was conducted on panoramic images of 110 patients (36 females, 74 males) between 20 and 35 years of age through fractal analysis method by determination of two regions of interest (ROI) (the right toothed and right gonial regions) through box counting method. The case and control groups each of which included 55 individuals were comparable for age and gender. Spearman's rho analysis was implemented in order to analyze the correlation between FD measurements and package/year values of the smokers. The FD measurements of the case groups and control groups were matched through Mann-Whitney U Test. Any p value below 0.05 (p<0.05) were assessed as significant.
Results
FD analysis was conducted on 220 (110x2) ROIs of 110 individuals. There was not any statistically significant difference detected between FDs of the case and control groups. The correlation analysis of package/year values of the smoker individuals and FD measurements revealed a negative correlation which was not statistically significant (p>0.05).
Conclusion
Smoking does not cause a FD change in trabecular bone formation of the mandible. Since passive smoking, nutritional habits and unilateral chewing characteristics of the individuals may affect the trabecular formation, inclusion of such parameters in further studies would be useful.
Perception of mHealth Intervention for Psychoeducational Support Among Nigerian Women Receiving Chemotherapy for Breast Cancer: A Qualitative Study
Authors: Akingbade Oluwadamilare , Adediran Victoria , Somoye Ibironke Elizabeth , Alade Adetutu Sefinat , Chow Ka Ming
Published: February 2022

Background Women diagnosed with BC receiving chemotherapy have reported various side effects, which adversely affect their psychological state. Evidence suggests that psychoeducational interventions (PEIs) delivered through mobile phones might effectively provide psychosocial support for this population. However, there is a lack of evidence on Nigerian women's perception of mHealth PEI, which prompted this study.MethodA multi-centre exploratory qualitative study was conducted among women with BC who had completed chemotherapy at two tertiary hospitals in Nigeria. Face-to-face focus group interviews were conducted at the oncology clinics. Data were collected using a semi-structured interview guide until data saturation was reached. Data were analysed using thematic analysis. Results Thirty-two women were recruited, with seven focus group interviews conducted. The participants were between 22 and 75 years old and mostly diagnosed with Stage III BC. Four main themes emerged from the data analysis, including experiences of BC diagnosis and treatment phase, patients’ needs during chemotherapy, coping with chemotherapy and perception of mHealth intervention for psychoeducational support. The participants found that mHealth intervention is acceptable, and the suggested contents include information on chemotherapy, how to deal with the fear of chemotherapy, nutritious diet locally available and information on exercise.Conclusion BC diagnosis was devastating, and psychological disturbances were experienced while receiving chemotherapy, but the participants perceived that mHealth intervention could provide psychological and informational support. This study will help design a culturally appropriate mHealth PEI for this population.
Effect of Folic Acid Conjugated Silver Nanoparticles in Treatment of RA like Adjuvant Arthritis in Rats
Authors: Ahmed Hajar K. , Elbeialy Adel A. , Mansour Ahmad M. , Elzomor Hala , Abosaif Amany I.
Published: February 2022

Objective: Nanomedicine has become one of the promising research areas, opening new horizons in disease diagnosis and treatment. Recent years have witnessed a surge in the development of nanomedicine for combating rheumatoid arthritis (RA), the most common autoimmune arthritis. RA is characterized by progressive inflammation and persistent synovitis, leading to joint destruction, functional incapability, and ultimately disability. Although there has been a tremendous evolution in disease assess¬ment and treatment, many patients still fail to attain remission. Therefore, developing new drugs that specifically target inflamed joints and simultaneously attenuate other possible damages to healthy tissues is indispensable. This study was done to evaluate the potential of folic acid conjugated silver nanoparticles (FA-AgNPs) as RA therapy.Methods: In the CFA-arthritic rat model, FA-AgNPs & methotrexate were administered for 8 consecutive weeks. Therapeutic efficacy was evaluated by measuring paw volume, ESR, CRP, TNF-α, and IL-6 levels. For safety concerns, CBC, liver, and renal function tests were evaluated. Joints histological assessment was also carried out.Results: FA-AgNPs significantly reduced paw volume, paw weight, ESR, CRP, RF, TNF-α, and IL-6 levels compared with arthritic non-treated rats, demonstrating good anti-inflammatory activity. Likewise, histology of tarsal joints depicted comparatively lesser inflammatory cellular infiltration and diminished cartilage erosions. Methotrexate displayed comparable results. In contrast to methotrexate, FA-AgNPs showed normal CBC & significantly improved liver and renal function tests. Conclusion: FA-AgNPs exhibited substantial anti-arthritic activity. This notable anti-arthritic potential of FA-AgNPs was as good as the current standard treatment of MTX with higher biosafety.
Evaluation of General and Specific Combining Ability for Doubled Haploid Lines in Sweet Pepper (Capsicum Annuum L.)
Authors: Bayati Azam Zare , Shariatpanahi Mehran E. , Mostafavi Khodadad , Miri Seied Mehdi
Published: February 2022

Hybrid cultivars are commercially and economically important; hence, too much effort needed to improve the quality and quantity of hybrids. In this research project, general (GCA) and specific (SCA) combining ability of 32 doubled haploid (DH) lines of sweet pepper produced via microspore embryogenesis were evaluated. The DH lines were crossed with the top cross parent as the tester to evaluate general combining ability (GCA). Traits including morphological and yield-related characteristics to assess the general combining ability of lines were recorded and analyzed. The half-diallel mating crosses were performed using GCA based on the selected seven DH lines for SCA evaluation. Mean squares of GCA and SCA values were highly significant for most of the characters. DH55 line indicated the highest positive GCA for average yield per plant, moreover, the highest positive SCA was obtained for 55×64 hybrid. The ratio of \(\frac{MS \left(GCA\right)}{MS \left(SCA\right)}\) showed the non-additive gene actions in controlling all traits except fruit width and length and seed fresh weight. According to the results of specific combining ability of DH lines, four F1 hybrids were selected for new cultivar registration. The results obtained in the present study are applicable to release new F1- hybrids, which can be more reliable than those hybrids introduced by conventional selfing programs in sweet pepper due to 100% genetic purity of DH lines.
A novel missense mutation in the SLC26A4 gene in a chinese family with enlarged vestibular aqueducts
Authors: He Xiaohui , Zhao Shaozhi , Shi Lin , Lu Yitong , Yang Yintong , Zhang Xinwen
Published: February 2022

Background: SLC26A4 gene is closely related to enlarged vestibular aqueducts. Its homozygous mutation or compound heterozygous mutation may cause deafness and seriously affect the patient's life. As far as we know, this is the first reported pathogenic or probable pathogenic for the missense mutation. Our studies expand the mutation site of SLC26A4 gene and provide genetic counseling for the patient's family.Methods: The patients who came to our hospital for hearing test and accompanied by bilateral hearing abnormalities were collected for 15 genetic tests for hereditary deafness. Those who are positive on chip screening will be verified by first-generation sequencing, combined with family history, hearing test, and computerized tomography (CT) of the temporal bone to diagnose the enlarged vestibular aqueducts. If necessary, perform second-generation sequencing.Results: The patient failed the two hearing screenings on both sides, computerized tomography diagnosed enlarged vestibular aqueduct (>1.5 mm). Two pathogenic mutations, c.1174A>T and c.2069T>A were detected in SLC26A4. The heterozygous c.2069T>A mutation of SLC26A4 gene is a novel missense mutation that has been submitted to the clinvar website, Variation ID：1048780.Conclusion: Our findings enriched SLC26A4 gene spectrum and support previous studies that the enlarged vestibular aqueducts can be caused by a compound heterozygous mutation in SLC26A4.
Optimizing plant density and balancing NPK inputs in combination with innovative fertilizer product for sustainable maize production in North China Plain.
Authors: Zhao Shuaixiang , Feyissa Tesema , Hailong Ma , Zhiping Duan , Zhang Weifeng
Published: February 2022

Excessive NPK inputs but low grain yield and high environmental impact are common in maize production in North China Plain (NCP). The objective of our study was to test whether a combined strategy of optimizing plant density, balancing NPK input, and innovating one-time fertilizer products could achieve a more sustainable maize production in NCP. Thus, a field experiment was conducted at Luanna County NCP with the treatments of unfertilized control (CK), farmer practice (FP, conventional plant density and NPK input), conventional one-time urea-based coated fertilizer (CF, optimized plant density and NPK input), and five newly designed innovative one-time NPK fertilizers of ammonium sulphate and urea synergy (IF, optimized plant density and NPK input), innovative fertilizer with various additives of urea inhibitors (IF+UI), double inhibitors (IF+DI), micro-organisms (IF+MI), and trace elements (IF+TE). The grain yield, nitrogen sustainability indicators (nitrogen use efficiency NUE, partial factor productivity of nitrogen PFPN, and nitrogen surplus), and cost-benefits analysis were measured and calculated over the maize growing season of 2020. Results had shown that on average the five innovative fertilizers (IF, IF+UI, IF+DI, IF+MI, and IF+TE) and CF that had optimized plant density and NPK input achieved 13.5%, 98.6%, 105.9%, 37.4% higher yield, PFPN, NUE, net-benefits as well as 67.5% lower N surplus compared with FP respectively. Notably, the innovative fertilizer with various effective additives (IF+UI, IF+DI, IF+MI, and IF+TE) which can be commonly found in the fertilizer market hadn’t resulted in an improvement in yield and NUE rather a greater cost and small net benefits in comparison to IF. In summary, our study highlighted the effectiveness of the combined strategy of optimized plant density, balancing NPK input, and innovative NPK products on sustainable maize production in NCP, however, the innovative fertilizers with effective additives should be properly selected for better economic benefits.
Predicting personal risk of developing breast and prostate cancer from routine check-up data using survival analysis trees
Authors: Coster Dan , Fisher Eyal , Shenhar-Tsarfaty Shani , Menes Tehillah , Berliner Shlomo , Rogowski Ori , Zeltser David , Shapira Itzhak , Halperin Eran , Rosset Saharon , Gorfine Malka , Shamir Ron
Published: February 2022

The challenge of survival prediction is ubiquitous in industry and medicine. Few methods are available for survival prediction of time varying data. Here we propose a novel method for this problem, using a random forest of survival trees for left truncated and right-censored data. We demonstrated the advantage of our method on prediction of breast cancer and prostate gland cancer risk among healthy individuals by analyzing routine laboratory measurements, vital signs and age. We analyzed electronic medical records of 20,317 healthy individuals who underwent routine checkups and identified those who later developed cancer. In cross-validation, our method predicted future prostate and breast cancers six months before diagnosis with an area under the ROC curve of 0.62±0.05 and 0.6±0.03 respectively, outperforming standard random forest, Cox-regression model and a single survival tree. Our results suggest that computational analysis of data on healthy individuals can improve the detection of those at risk of future cancer development.