bluuebunny/crossref_metadata_2025 huggingface dataset:
Clinical Guidelines and Implementation into Daily Dental Practice
Authors: Guncu Guliz Nigar , Karakoca Nemli Secil , Carrilho Eunice , Yamalık Nermin , Volodina Elena , Melo Paulo , Margvelashvili Vladimer , Rossi Alessandra
Published: January 2018

Introduction: The purpose of this study is to assess the extent of the familiarity, attitude and perceptions of dental professionals regarding clinical dental guidelines and their implementation into daily dental practice.Material and Methods: For this purpose, a questionnaire which was developed by the members of the World Dental Federation, European Regional Organization Working Group − ‘Relation Between Dental Practitioner and Universities’, was implemented by the National Dental Associations of six European Regional Organization-zone countries (Georgian Stomatological Association - Georgia, Associazione Nazionale Dentisti Italiani - Italy, Portuguese Dental Association - Portugal, Russian Dental Association - Russia, Swiss Dental Association - Switzerland, and Turkish Dental Association - Turkey. The questionnaire was filled by a total of 910 dental professionals who are members of one of these national dental associations and who voluntarily wanted to participate to this survey. Results: Most of the survey participants were familiar with clinical dental guidelines (68%), claimed that they implemented them into daily practice (61.7%), and generally acknowledged their benefits (81.8%). Many participants believed that clinical dental guidelines could help to improve the clinical treatment plan (50.6 %) and the accuracy of diagnosis (39.4%); which increased with age and years of practice (p < 0.05). The most frequently perceived barrier to the effective implementation of clinical dental guidelines was expressed as ‘lack of awareness’, while participants suggested a role for national dental associations in spreading clinical dental guidelines.Discussion: A better understanding of the perceptions and attitudes of dentists towards clinical dental guidelines and the potential impact of factors affecting such perceptions and attitudes may be of particular importance for attempts aiming at overcoming the barriers for effective implementation of clinical dental guidelines into daily practice.Conclusion: Despite a significant familiarity and a common positive attitude, dental professionals are likely to have different perceptions towards clinical dental guidelines, especially regarding their effective implementation into daily practice, benefits and barriers.
Mortality from Suicide in the Municipalities of Mainland Portugal: Spatio-Temporal Evolution between 1980 and 2015
Authors: Loureiro Adriana , Almendra Ricardo , Costa Cláudia , Santana Paula
Published: January 2018

Introduction: Suicide is considered a public health priority. It is a complex phenomenon resulting from the interaction of several factors, which do not depend solely on individual conditions. This study analyzes the spatio-temporal evolution of suicide mortality between 1980 and 2015, identifying areas of high risk, and their variation, in the 278 municipalities of Continental Portugal.Material and Methods: Based on the number of self-inflicted injuries and deaths from suicide and the resident population, the spatio-temporal evolution of the suicide mortality rate was assessed via: i) a Poisson joinpoint regression model, and ii) spatio-temporal clustering methods.Results: The suicide mortality rate evolution showed statistically significant increases over three periods (1980 - 1984; 1999 - 2002 and 2006 - 2015) and two statistically significant periods of decrease (1984 - 1995 and 1995 - 1999). The spatio-temporal analysis identified five clusters of high suicide risk (relative risk >1) and four clusters of low suicide risk (relative risk < 1).Discussion: The periods when suicide mortality increases seem to overlap with times of economic and financial instability. The geographical pattern of suicide risk has changed: presently, the suicide rates from the municipalities in the Center and North are showing more similarity with those seen in the South, thus increasing the ruralization of the phenomenon of suicide.Conclusion: Between 1980 and 2015 the spacio-temporal pattern of mortality from suicide has been changing and is a phenomenon that is currently experiencing a growing trend (since 2006) and is of higher risk in rural areas.
SOP Model Based on Employment Instruction from EMI Results to Improve the Satisfaction of Higher Education Service
Authors: Uchtiawati Sri
Published: January 2018

This study aim for analyze satisfaction Higher education service which is a form of servant performed by managers to stakeholders, based on Internal Quality Evaluation (EMI) result, from EMI achievement, set the Standard Operational Procedure and Work Instruction model, given the satisfaction of service is a very important part. The research method is correlation with the indicator consist of standard of Content, Process, Competence of graduates, Educator and educational staff, Facilities and infrastructure of Education, Management of Prodi, Financing, Assessment, Research and Community Service, then, from EMI standard, correlated with stakeholders' satisfaction, with satisfaction level determined by category (a) satisfactory, if Expected Service / ES = Perceived Service (PS), (b) is not satisfactory when perceived service is lower than expectation (ES ≥ PS) and (c) very satisfying/happy when the service is perceived to exceed expectations (PS≥ES), and then performed data analysis. To define the model using several stages of the 4-D model include stages, definitions, design, development, and use or application. The result of correlation on study program A and study program B and Islamic education are different, for study program A is Competency Standard of Graduates (X3) with regression coefficient b3 = 0,076 and correlation coefficient R3 = 0,186, while study program B is Graduate Competency Standard (X 3) with regression coefficient b 3 = 0,138 with correlation coefficient R 3 = 0,183, while indicator education according to government’s provision, which has correlation level at graduate level. The results of this research become the basis in determining SOP Model and Work Instruction, which then tested at universities studied, and in general the application of this model is in the category of Satisfactory.
Synthesis, X-ray Crystal Structures, Computational Studies and Catechol Oxidase Activity of New Acylhydrazone Derivatives
Authors: Karrouchi Khalid , Radi Smaail , El Bekkaye Yousfi , Sebbar Nada Kheira , Taoufik Jamal Taoufi , Ouzidan Younes , Ghabbour Hazem A. , Mabkhot Yahia , Al-Showiman Salim , Alterary Seham , Ansar M’hammed
Published: January 2018

To make low-cost catalytic materials that mimic the activity of tyrosinase enzymes (Catechol oxidase) is an exciting challenge of biochemical technology. Herein, we report the synthesis of a series of acylhydrazone-pyrazoles based biomolecule materials (L1-L7) with superior catecholase activity. These biomolecules were synthesized by a one pot chemical condensation between 5-methyl-1H-pyrazole-3-carbohydrazide and benzaldehyde derivatives. The X-ray single crystal diffraction (XRD) for two ligands L1 and L2 have been studied and the molecular structures were optimized and confirmed using the density functional theory (DFT/B3LYP) method. Copper (II) complexes of the biomolecules (L1-L7), generated in-situ, and were studied for their catalytic activities towards the oxidation reaction of catechol to ortho-quinone according to two parameters: the nature of the ligand and the nature of counter anion. The L7-CuSO4 was found to have an excellent catalytic activity (105.42 μmol·L−1·min−1) among the catalysts recently reported in the existing literature.
Circular Array of Magnetic Sensors for Current Measurement: Analysis for Error Caused by Position of Conductor
Authors: Yu Hao , Qian Zheng , Liu Huayi , Qu Jiaqi
Published: January 2018

This paper analyzes the measurement error, caused by the position of the current-carrying conductor, of circular array of magnetic sensors for current measurement. The circular array of magnetic sensors is an effective approach for AC or DC non-contact measurement, as its low cost, large linear range, wide bandwidth, light weight and low noise. Especially it has claimed that such structure has the excellent reduction ability for the errors caused by the position of the current-carrying conductor, crosstalk current interference, shape of the conduction cross section and the earth magnetic field. However, the positions of the current-carrying conductor, including un-center and un-perpendicularity, has not analyzed in detail until now. In this paper, the theoretical analysis has been proposed based on vector inner and exterior product. In the presented mathematical model of relative error, the un-center offset distance, the un-perpendicular angle, the radius of the circle and the number of the magnetic sensor are expressed in one equation. The comparison of the relative error caused by the position of the current-carrying conductor between four and eight sensors is conducted. The Tunnel Magnetoresistance (TMR) sensors are used in the experimental prototype to verify the mathematical model. The analysis results can be the reference to design the detail of circular array of magnetic sensors for current measurement in practical situation.
Community Consensus: Why the Fracturing Craze?
Authors: Spady Darcy
Published: January 2018

President's column

Moving technology at the same speed as economics.

Did you know that fracturing is not permitted in parts of the Middle East? And it has been that way for a long time. Hydraulic fracturing is not a global norm, although with the rise of unconventional resources, some jurisdictions are rewriting the legislation to allow fracturing.

I have watched hydraulic fracturing grow from the workover option of stimulating an old well and reducing the skin factor to the current state of being part of every field’s development from the new well construction stage. What I fear is that sometimes as technical people we have been guilty of “photocopy engineering.” We are all about efficiency, so if it worked once, it should work the same for the next 1,000 times. Right?

Fracturing has become all about repetition and iteration. It may not be the best option.

Now in all fairness, before some of you slam shut this magazine and tear up your SPE membership card, let me give a few disclaimers. First, I have spent about half of my career performing fracturing treatments on location and designing, selling, and paying for fracs through the authority for expenditure (AFE) process. In fact, in the 1990s when I was the engineer in charge of the data van during treatments, we had the best and freshest coffee on location.

Second, our industry is what it is today—and a large amount of hydrocarbon is being consumed on a global scale—because of the incredible technological gains developed in fracturing. Third, I have been featured and vilified as the bad guy on anti-fracking websites, and it does not feel very good. Fourth, it is incredibly satisfying to witness a pure economic driver such as new production from old fields cause the commodity markets to wobble and thus rewrite the norm. The story of my colleagues and me at Triana Energy in the Appalachians is even featured in Chapter 9 of the bestseller by Gregory Zuckerman, The Frackers.

Having now stated that I am part of the “they,” meaning those who help to develop and utilize hydraulic fracturing, including writing paper SPE 57435 about multizone stimulation using coiled tubing, I will get off my soapbox and make my point.

Over the last few months, two stories got my attention. My local paper had a headline from Bloomberg reading “All that new shale oil may not be enough as big discoveries drop.” And, over the holiday season, Weatherford announced the sale of its OneStim joint venture to Schlumberger. The moving and shaking in the North American fracturing market always makes me ponder the bigger picture, and these two articles made me think a little. Having been involved in fracturing and the unconventional high-efficiency plays for over half of my career, I tend to watch that space very carefully. It is part of a world that I understand well.
Drilling-Fluid Behavior During Reservoir-Formation Drilling and Completion
Authors: Carpenter Chris
Published: January 2018

This article, written by JPT Technology Editor Chris Carpenter, contains highlights of paper SPE 185889, “The Nature of Drilling-Fluid Invasion, Cleanup, and Retention During Reservoir-Formation Drilling and Completion,” by Justin Green, Ian Patey, and Leigh Wright, Corex; Luca Carazza, Aker BP; and Arild Saasen, University of Stavanger, prepared for the 2017 SPE Bergen One Day Seminar, Bergen, Norway, 5 April. The paper has not been peer reviewed.

A reservoir-conditions coreflood study was undertaken to assist with design of drilling and completion fluids for a Norwegian field. Multiple fluids were tested, and the lowest permeability alterations did not correlate with the lowest drilling-fluid-filtrate-loss volumes. This paper will examine the factors that contributed to alterations in the core samples.

Introduction

A range of measurements are made during reservoir-condition studies, with typical metrics of the performance of a fluid or sequence including the following:

Permeability measurements are made at initial reservoir conditions and then again at various points throughout the study.

Filtrate-loss volumes are used to compare the performance of various fluid types, including bridging design (drilling fluids), activation of crosslinked gels (kill pills), and breakthrough time/rate (treatment fluids).

Production/injection rates or differential pressures can give some broad indications of cleanup but are generally prone to artifacts or misinterpretation caused by multiple mechanisms occurring simultaneously within samples.

Visual observations can give an excellent overview of external features of the samples such as drilling-mudcake cleanup and sanding or sample failure or fracturing. However, they do not show what changes have occurred within samples and cannot visualize changes at a microscopic level, and both are generally key to understanding results.

These metrics are unfortunately subject to a number of factors that make interpretation difficult and therefore add risks to the decision-making process. In order to reduce these risks, a number of interpretive techniques are used. These include scanning electron microscopy (SEM), thin sections, and computed-tomography (CT) scanning.

In order to overcome some of the limitations posed by existing techniques, a micro-CT change-mapping technique was developed to show the distribution of alterations within samples at selected points in a study.

Do Filtrate Loss Volumes Tell Us How a Drilling Fluid Is Performing?

In terms of aiding operational decisions, the remaining mudcake attachment after a period of production or injection is most relevant in maximizing hydrocarbon recovery. The cleanup of drilling mudcakes will be influenced by a range of factors. An approach that allows a holistic view of the changes related to drilling fluid, taking into account as many relevant factors as possible, is therefore desirable.
Current trends in global demographic processes
Authors: Sardak Sergii , Korneyev Maxim , Dzhyndzhoian Vladimir , Fedotova Tatyana , Tryfonova Olha
Published: January 2018

Current local and national demographic trends have deepened the existing and formed new global demographic processes that have received a new historical reasoning that requires deep scientific research taking into account the influence of the multifactorial global dimension of the modern society development. The purpose of the article is to study the development of global demographic processes and to define the causes of their occurrence, manifestations, implications and prospects for implementation in the first half of the 21st century. The authors have identified and characterized four global demographic processes, namely population growth, migration, increase of tourism, and change in population structure. It is projected that in the 30’s of the 21st century, the number and growth rates of the world population will reach the objective growth and these dynamics over the next two decades will begin to change in the direction of reducing the growth rates, which will lead to gradual stabilization, and eventually reduce the size of the world population. By the middle of the 21st century, one can observe the preservation of the growth rates of international and domestic migration, the growth of international migration flows from the South to the North and from the East to the West, the strengthening of new economically developed centers of gravity (Canada, Australia and New Zealand), the increase in migration of rural population to cities, as well as urbanization and activation of the metropolises development. The share of international tourists in comparison with the world population will be constantly increasing, and the annual growth rate of the number of international tourists will significantly depend on the world economy and may vary at the several percent level. Permanent change will occur in the age, religious-cultural and socio-economic structure of the population.
Formation of the national tourism system of Ukraine
Authors: Mazaraki Anatoly , Boiko Margarita , Bosovska Myroslava , Vedmid Nadiia , Okhrimenko Alla
Published: January 2018

Tourism is an important factor in the development of the national economy. The share of tourism in the structure of Ukraine’s GDP is 7.8%. Ukraine, having a considerable tourist potential for the formation of tourist flows, is ranked 85th among 139 countries of the world in terms of tourism attractiveness. According to the findings of the World Tourism Organization (UNWTO), the concentration of natural and recreational resources, objects of the world cultural and historical heritage can provide an annual increase in tourist flows to Ukraine by 4-6%.Under the conditions of unstable external environment and unfavorable conditions of the tourism market, an actual scientific task is to develop the theoretical and applied basis for the formation of the national tourism system. Conceptually, this process must be consistent with the strategic understanding of the need to take into account the mental, institutional, cultural and informational influences on the economic interests of entities, which form a functional, sectoral, socio-economic, institutional and environmental subsystem of the national tourism system. This will make it possible to determine target priorities of such activity not only in accordance with the development of destinations, but also taking into account the possibility of obtaining socio-economic effects, in particular, synergistic, multiplicative and cumulative ones.The goal of the study is to substantiate the essence of the national tourism system (NTS) based on the comparative analysis of the definitions of “tourism”, “tourism system”, “economic system”, “national socio-economic system”, which became a scientific foundation for determining the scientific basis of the national tourism system, its subjects and objects, conditions, goals, and results of formation. For the science development it is also important to obtain results on the structure and evaluation of the national tourism system effectiveness.
The occurrence of albinism in roe deer: A case study
Authors: FLIS MARIAN , GRELA EUGENIUSZ R. , GUGAŁA DARIUSZ , RATAJ BOGUSŁAW
Published: January 2018

Two cases of albinism in roe deer were reported in the Lublin region in the spring of 2017. Both animals were females. One of them was a mature female roe deer with partial albinism. The other was a young roe deer (kid) born in the previous hunting season, which was a true albino, most probably descended from a female roe deer with pseudo-leukoderma. Since the eyes of these animals could not be examined, it was impossible to conclude about their leucism. No male roe deer in a group of 14 animals showed phenotypic features of albinism. This confirms that albinism in roe deer occurs very rarely, because it is conditioned by recessive alleles, and its phenotypic manifestations can take many forms..
Smallholder Organic Farming: An Entrepreneurial Strategy in Harmony with Nature
Authors: Magnaye Dina Cartagena
Published: January 2018

The paper examines the relationship between smallholder organic farming and entrepreneurship taking into account the environmental conservation approach of organic farming and the economic enhancement features of entrepreneurship. Further, it intends to determine through qualitative analysis using case studies how smallholder organic farming can be planned and the competencies needed by an organic farmer when venturing into an organic farm enterprise.
Spatio-temporal relational evaluation of the Beijing water crisis and planning implementation from 1949 to 2013
Authors: Fu Wei , Yu Kongjian , Li Dihua
Published: January 2018

Due to a lack of evaluation of the implementation of water planning policies, based on long-term spatio-temporal analysis, this research uses Beijing as an empirical case study to bridge this gap. We analyze the spatio-temporal evolution of water problems and water planning implementations. Content analysis, cluster analysis, and spatial interpolation analysis are used to illustrate the spatio-temporal evolution of water planning implementation. In addition, a grey relational model is developed to determine the impact of the most relevant implementation objects on each water issue. The results indicate that the Beijing water crisis evolves from the center outwards in a planar expansion. However, the water plan implementation shows linear and point characteristics. The majority of implementation categories consist of single-function infrastructure. The implemented categories ‘which show a significant implementation peak’ influence more than one water issue. The categories ‘that were implemented at a steady rate’ have a high relational grade with both surface and underground water shortage problems. Different implementation types from different planning categories may have simultaneous effects on one kind of water problem. Thus, improving water governance is the key to water security in Beijing. This study may serve as a reference for future water planning in other cities.
Sulphur-containing Amino Acids: Protective Role Against Free Radicals and Heavy Metals
Authors: Colovic Mirjana B. , Vasic Vesna M. , Djuric Dragan M. , Krstic Danijela Z.
Published: January 2018

Background:

Sulphur is an abundant element in biological systems, which plays an
important role in processes essential for life as a constituent of proteins, vitamins and other crucial
biomolecules. The major source of sulphur for humans is plants being able to use inorganic
sulphur in the purpose of sulphur-containing amino acids synthesis. Sulphur-containing amino
acids include methionine, cysteine, homocysteine, and taurine. Methionine and cysteine are classified
as proteinogenic, canonic amino acids incorporated in protein structure. Sulphur amino acids
are involved in the synthesis of intracellular antioxidants such as glutathione and N-acetyl
cysteine. Moreover, naturally occurring sulphur-containing ligands are effective and safe detoxifying
agents, often used in order to prevent toxic metal ions effects and their accumulation in
human body.

Methods:

Literature search for peer-reviewed articles was performed using PubMed and Scopus
databases, and utilizing appropriate keywords.

Results:

This review is focused on sulphur-containing amino acids – methionine, cysteine,
taurine, and their derivatives – glutathione and N-acetylcysteine, and their defense effects as antioxidant
agents against free radicals. Additionally, the protective effects of sulphur-containing
ligands against the toxic effects of heavy and transition metal ions, and their reactivation role towards
the enzyme inhibition are described.

Conclusion:

Sulphur-containing amino acids represent a powerful part of cell antioxidant system.
Thus, they are essential in the maintenance of normal cellular functions and health. In addition
to their worthy antioxidant action, sulphur-containing amino acids may offer a chelating site
for heavy metals. Accordingly, they may be supplemented during chelating therapy, providing
beneficial effects in eliminating toxic metals.
Attenuation of Diabetes-induced Cardiac and Subcellular Defects by Sulphur-containing Amino Acids
Authors: Tappia Paramjit S. , Adameova Adriana , Dhalla Naranjan S.
Published: January 2018

Background:

Patients with diabetes mellitus have an increased risk of mortality
due to cardiovascular complications. Supplementation with specific sulphur-containing
amino acids is rapidly emerging as a possible therapeutic adjuvant for diabetes
and associated cardiovascular complications.

Observations:

It is well-known that oxidative stress plays an important role in the pathogenesis
of diabetes-induced cardiovascular disease, which is invariably associated with
abnormal blood lipid profile, insulin resistance and other symptoms of metabolic syndrome.
Cysteine and taurine are among the most common sulphur-containing amino acids
and their cellular levels decline during diabetes that may contribute to the development of
the cardiomyopathy. Although sulphur-containing agents exert multiple actions on cellular
and subcellular functions in the heart, they also exhibit antioxidant properties and thus
may exert beneficial effects in different pathophysiological conditions.

Conclusion:

It is concluded that reduction of oxidative stress by cysteine and taurine may
serve as an important mechanism for the attenuation of diabetes-induced subcellular and
functional abnormalities in the heart.
Polyphenols: Potential Use in the Prevention and Treatment of Cardiovascular Diseases
Authors: Giglio Rosaria Vincenza , Patti Angelo Maria , Cicero Arrigo F.G. , Lippi Giuseppe , Rizzo Manfredi , Toth Peter P. , Banach Maciej
Published: January 2018

Background:

Polyphenols are bioactive compounds that can be found mostly in foods like fruits, cereals,
vegetables, dry legumes, chocolate and beverages such as coffee, tea and wine. They are extensively used in
the prevention and treatment of cardiovascular disease (CVD) providing protection against many chronic illnesses.
Their effects on human health depend on the amount consumed and on their bioavailability. Many studies
have demonstrated that polyphenols have also good effects on the vascular system by lowering blood pressure,
improving endothelial function, increasing antioxidant defences, inhibiting platelet aggregation and low-density
lipoprotein oxidation, and reducing inflammatory responses.

Methods:

This review is focused on some groups of polyphenols and their effects on several cardiovascular risk
factors such as hypertension, oxidative stress, atherogenesis, endothelial dysfunction, carotid artery intima-media
thickness, diabetes and lipid disorders.

Results:

It is proved that these compounds have many cardio protective functions: they alter hepatic cholesterol
absorption, triglyceride biosynthesis and lipoprotein secretion, the processing of lipoproteins in plasma, and inflammation.
In some cases, human long-term studies did not show conclusive results because they lacked in appropriate
controls and in an undefined polyphenol dosing regimen.

Conclusion:

Rigorous evidence is necessary to demonstrate whether or not polyphenols beneficially impact CVD
prevention and treatment.
Melatonin Differentially Modulates NF-кB Expression in Breast and Liver Cancer Cells
Authors: Colombo Jucimara , Jardim-Perassi Bruna V. , Ferreira João P.S. , Braga Cristine Z. , Sonehara Nathália M. , Júnior Rubens P. , Moschetta Marina G. , Girol Ana P. , Zuccari Debora A.P.C.
Published: January 2018

Background:

NF-kB (nuclear factor kappa B) is a transcription factor composed of two subunits, p50
and p65, which plays a key role in the inflammatory process. Melatonin has oncostatic, antiangiogenic and
antimetastatic properties, and some recent studies have indicated an inhibitory effect of melatonin on NF-kB in
some types of cancer. This work aims to investigate the effects of melatonin treatment on the expression of NFkB
in breast and liver cancer models.

Method:

The breast cancer xenographic model was performed using female Balb/c nude athymic mice injected
with MDA-MB-231 cells. The animals were treated with 40 mg/Kg of melatonin for 21 days. Volume of the
tumors was measured with a digital caliper. Hepatocarcinoma model was developed by using the HepG2 cells in
vitro, treated with 1 mM melatonin for 24 h. The expression of NF-kB protein was verified by immunohistochemistry
and immunocytochemistry and quantified by optical densitometry, in vivo study and in vitro study,
respectively. NF-kB gene expression was performed by quantitative RT-PCR.

Results:

The breast cancer xenografts nude mice treated with melatonin showed reduced tumor size (P=0.0022).
There was a decrease in NF-kB protein staining (P=0.0027) and gene expression (P=0.0185) in mice treated
with melatonin. The opposite results were observed for the hepatocarcinoma model. HepG2 cells treated with
melatonin showed an increase in the NF-kB immunostaining when compared to control cells (P=0.0042).

Conclusion:

Our results indicated that the treatment with melatonin was able to decrease both gene and protein
expressions of NF-kB in breast cancer cells and, conversely, increase the transcription factor protein expression
in hepatocarcinoma cells. These data highlighted a double role in the expression of NF-kB, depending on the
cell type. Further studies are needed to better elucidate the action of melatonin in NF-kB, since this transcription
factor acts on different signaling pathways that are fundamental for carcinogenesis.
Characterization of the Visual Disability and Its Relation with the Resilience
Authors: Cedeño María Leonila García , Rosado Inger Solange Maitta , Loor Karina Gissela Rivera
Published: January 2018

The objective of the work is to determine the characterization of the visual disability and its relation with the resilience in the students of the Technical University of Manabí. The work shows an analysis of the visual disability in students and its impact on the level of resilience. An analysis of resilience is addressed regarding the physical and mental state of the people, as well as the process of adapting to the problems and adversities of life. The results are shown in tables and graph on the analysis of the degree of visual disability of the students, as well as the application of the SV-RES test prepared by the researchers Saavedra & Villalta, 2008. Based on the evaluation of 12 dimensions, which allow verifying the situation according to three scales: high, average and low. Finally, the conclusions are offered where the objective stated in the investigation is verified.
In-vitro antioxidant and anti-inflammatory potential of Ethanol extracts (root and aerial parts) of Barleria noctiflora
Authors: M.S. Manjula , Ganthi Saravana
Published: January 2018

Barleria noctiflora L.f. (Acanthaceae) is widely used as folk medicine. In the present study ethanol extracts of root and aerial parts of Barleria noctiflora were prepared using soxhlet extractor. Anti-oxidant potential was evaluated by free radical scavenging activity on DPPH and in vitro anti- inflammation activity of the selected samples stood determined by inhibition of protein denaturation experiment and inhibition of α-amylase studies. Among the root and aerial parts of Barleria noctiflora samples root sample shows significantly high level of antioxidant and anti-inflammatory activity.
Use of Progress Testing in a UK Dental Therapy and Hygiene Educational Program
Authors: Ali Kamran , Zahra Daniel , Tredwin Christopher , McIlwaine Claire , Jones Gill
Published: January 2018

Progress testing provides a longitudinal assessment of the development and sustainability of students’ knowledge at regular intervals over the duration of an educational program. Comparisons of performance on successive tests are used to monitor growth in knowledge. The aim of this study was to evaluate the effects of progress testing in an undergraduate program for dental therapy and hygiene (DTH) students in the United Kingdom as the main tool for academic assessment. Data were collected for progress tests of all 38 DTH students from 2015 to 2017. Each test consisted of 100 single best answer multiple‐choice items with accompanying vignette. The students chose their answer from five options. A score of 1 was awarded for a correct answer, −0.25 for an incorrect answer, and 0 for don't know (DK). Three cohorts of DTH students were included in the study, and seven progress tests were conducted over a period of three years. Analysis of performance showed growth in knowledge across successive years, with the largest increase in knowledge in the transition from Year 1 to Year 2 and concomitant reduction in incorrect and DK responses. This was a pioneering study to report the establishment and use of progress testing among undergraduate DTH students. Notwithstanding the challenges involved, the study found merit in further exploring the use of progress testing for students in the DTH program.
Sulfur containing activated hydantions. Synthesis and screening some novel benzylidenehydantoins amino acids derivatives
Authors: El-Sayed Ragab
Published: January 2018

5-Benzylidenehydantoin reacts with chlorosulfonic acid to give the
corresponding p-sulfonyl chloride 1. Condensation with nucleophiles gives
amino acid derivatives 2-7. Coupling reactions of some amino acid
derivatives (2-6) with amino acid methyl ester hydrochloride in THF-Et3N
medium using the dicyclohexylcarbodiimide method (DCC) furnish the desired
dipeptidemethyl esters 8-12. The spectral data of the synthesized compounds
are briefly discussed.
Thin-layer chromatography of several antihypertensive drugs from the group of angiotensin converting enzyme inhibitors
Authors: Aleksic Mirjana , Agbaba Danica , Baosic Rada , Milojkovic-Opsenica Dusanka , Tesic Zivoslav
Published: January 2018

Arapid and simple method for the chromatographic separation of
pharmacologically active components contained in some antihypertensive drugs
has been developed employing thin-layers of silica gel and polyacrylonitrile
sorbent (PANS). The active compounds of Captopril -
(S)-1-(3-mercapto-2-methyl-1-oxopropyl)-L-proline, Enalapril - (S)-1- N-
1-(ethoxycarbonyl)-3-phenylpropyl -L-alanyl -L-proline, Lisinopril - (S)
-1- N2-(carboxy-3-phenylpropyl)-L-lysyl-L-proline, Quinapril -
3S-2R
The determination of the content of gold and silver in geological samples
Authors: Petrovic N. , Budjelan D. , Cokic S. , Nesic B.
Published: January 2018

Amethod has been elaborated for the determination of the content of gold and
silver in geological samples by atomic absorption spectrophotometry (AAS) in
combination with the fire assay method. The weight of sample used for
analysis was 10 g. Sulphur present as sulphide, which is an undesirable
element in smelting, was removed by the addition of iron to the charge. The
sample was smelted with fluxes and lead oxide to replace the silver and gold
by lead and to transfer non-precious elements to slag. Lead was separated
from precious metals by cupellation. The separated silver and gold alloy was
dissolved with aqua regia with addition of hydrochloric acid in excess.
Silver and gold were determined from the same solution. For determination of
the silver content, the AAS method with an air-acetylene flamewas used.
Goldwas determined in a graphite furnace with the addition of a matrix
modifier in an argon current, at an atomization temperature of t = 2200 ?C.
The lower determination limit for silver was 0.05 g/t and for gold 0.005
g/t. The results of the analysis for silver and gold obtained with the
proposed method showed good agreement with the results of the analysis of
the same samples with the fire assay method.
The effect of electrodeposition process parameters on the current density distribution in an electrochemical cell
Authors: Popov K.I. , Stevanovic R.M. , Zivkovic P.M.
Published: January 2018

Cell voltage - current density dependences for a model electrochemical cell
of fixed geometry were calculated for different electrolyte conductivities,
Tafel slopes and cathodic exchange current densities. The ratio between the
current density at the part of the cathode nearest to the anode and the one
furthest away were taken as a measure for the estimation of the current
density distribution. The calculations reveal that increasing the
conductivity of the electrolyte, as well as increasing the cathodic Tafel
slope should both improve the current density distribution. Also, the
distribution should be better under total activation control or total
diffusion control rather than at mixed activation- diffusion-Ohmic control
of the deposition process. On the contrary, changes in the exchange current
density should not affect it. These results, being in agreement with common
knowledge about the influence of different parameters on the current
distribution in an electrochemical cell, demonstrate that a quick estimation
of the current distribution can be performed by a simple comparison of the
current density at the point of the cathode closest to anode with that at
furthest point.
Application of the log k pair linearity rule and proportionality rule to the RPP mobile phase scales estimation on cyano-silica column
Authors: Janjic Tomislav , Vuckovic Gordana , Celap Milenko
Published: January 2018

On the basis of literature-reported log k values, the Log k pair linearity
rule and the Proportionality rule were found to be also valid in the case of
cyano-silica sorbent, whenmethanol, acetonitrile or propane-2-olwere used as
modifiers. The RPPscales, reflecting the solvent strength, are in good
linear relationship with the experimentally determined log k values.
Furthermore, in the case of methanol and acetonitrile, the linear
dependence: log k = f(mol%of modifier) was also established. In the function
obtained in a such way, the intercept and the slope exhibit an approximate
linear dependence. Finally, in the case of methanol, the experimentally
obtained log k values are in a satisfactory agreement with the values
calculated by the above equation.
The application of near infrared reflectance spectroscopy (NIRS) for the quantitative analysis of hydrocortisone in primary materials
Authors: Nikolich K. , Sergides C. , Pittas A.
Published: January 2018

Near Infrared Reflectance Spectroscopy (NIRS), coupled with fiber optic
probes, has been shown to be a quick and reliable analytical tool for
quality assurance and quality control in the pharmaceutical industry, both
for verifications of raw materials and quantification of the active
ingredients in final products. In this paper, a typical pharmaceutical
product, hydrocortisone sodium succinate, is used as an example for the
application of NIR spectroscopy for quality control. In order to develop an
NIRS method with higher precision and accuracy than the official UV/VIS
spectroscopic method (BP '99), 19 samples, taken from one year?s production
and several prepared in the laboratory, having a hydrocortisone sodium
succinate concentration in the range from 89.05%to 95.83 %, were analysed by
NIR and UV/VIS spectroscopy. Three frequency ranges: 5939.73-5627.32 cm-1;
4863.64 - 4574.36 cm-1; 4308.23-4200.24 cm-1, with the best positive
correlation between the changes in the spectral and concentration data, were
chosen. The validity of the developed NIRS chemometric method for the
determination of the hydrocortisone sodium succinate concentration,
constructed by the partial least squares (PLS) regression technique, is
discussed. A correlation coefficient of 0.9758 and a standard error of cross
validation (RMSECV)of 1.06%were found between theUV/VISand
theNIRspectroscopic results of the hydrocortisone sodium succinate
concentration in the samples.
Mixing rules for excess free energy models
Authors: Djordjevic Bojan , Kijevcanin Mirjana , Orlovic Jadranka , Serbanovic Slobodan
Published: January 2018

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Carbon monoxide oxidation on a Au(111) surface modified by spontaneously deposited Ru
Authors: Strbac Svetlana , Magnussen Olaf , Behm Rolf-Jürgen
Published: January 2018

The spontaneous deposition of Ru on Au(111) was performed in 10-3MRuCl3 +
0.5MH2SO4 solution. The obtained surface was characterized by STM under
potential control in 0.5MH2SO4 solution. The coverage of the Au(111)
terraces by deposited Ru was estimated by STM to be 0.02 ML. Step decoration
could be noticed in the STM images, which indicates that the steps, as lined
defects, are active sites for the nucleation of Ru monolayer islands, while
the random distribution of Ru nuclei, observed on the terraces indicates
point defects as active sites. The electrocatalytic activity of Au(111)
surface modified by spontaneously deposited Ru was studied towards CO
oxidation. The significant enhancement in the reaction rate compared to CO
oxidation on a pure Au(111) surface, indicated that the edges of the
deposited Ru islands were the active sites for the reaction.
Synthesis and characterization of a novel (glycinato-N,O) yttrium(III) complex
Authors: Hodzic I.M. , Niketic S.R.
Published: January 2018

A novel yttrium(III) complex with glycine has been synthesized starting from
tris(ethanedioato-O,O)yttrium(III) by the substitution of the
acetylacetonato chelate ligands with glycine. The reaction product was
purified by ion-exchange chromatography and characterized on the basis of
infrared spectroscopy. The structure of the productwas tentatively
established as tris(glycinato-N,O)yttrium(III) dihydrate.
Enhancing film cooling effectiveness in a gas turbine end-wall with a passive semi cylindrical trench
Authors: Ravi Duraisamy , Parammasivam Kanjikovil
Published: January 2018

Computational studies were carried out in the end-wall of a linear cascade, of chosen blade profile, which is provided with one row of cylindrical film cooling holes inclined at 30o to the end wall. The CO gas was used as the coolant supplied through the film holes, 2 maintaining a blowing ratio of 0.6. The film cooling hole row was positioned at the leading edge of the cascade. The mainstream fluid was air and based on its properties at the cascade inlet, the flow was found turbulent. A semi cylindrical trench was placed at two positions upstream of the cascade leading edge and three positions downstream of it. ANSYS FLUENT 15.0 was used to compute the film cooling effectiveness of the cascade endwall. Trench positioned at a distance of twice that of film hole diameter, was found to show a highest increase of area averaged effectiveness value by 30.4% over the baseline. Further to this, the influence of the trench diameter was carried out where the trench with diameter twice that of film hole diameter was found to show a 31.3% increase of cooling effectiveness over the baseline. Studies on the influence of blowing ratio showed a highest increment of cooling effectiveness value by 43.5% over the baseline a blowing ratio of 1.2.
Energy and thermal modeling of building façade integrated photovoltaics
Authors: Ordoumpozanis Konstantinos , Theodosiou Theodoros , Bouris Dimitrios , Tsikaloudaki Katerina
Published: January 2018

Electricity generation on site is a design challenge aiming at supporting the concept of energy-autonomous building. Many projects worldwide have promoted the installation of photovoltaic panels on urban buildings, aiming at utilizing a large area to produce electricity. In most cases, photovoltaics are considered strictly as electricity generators, neglecting their effect to the efficiency and to the thermal behaviour of the building envelope. The integrated performance of photovoltaic ventilated fa?ades, where the photovoltaics are regarded as part of a complicated envelope system, provides design challenges and problems that cannot be overlooked within the framework of the Nearly Zero Energy Building concept. In this study, a finite volume model for photovoltaic ventilated fa?ades is developed, experimentally validated and found to have a significant convergence to measured data.
Exact solution to non-linear biological population model with fractional order
Authors: Bushnaq Samia , Ali Sajjad , Shah Kamal , Arif Muhammad
Published: January 2018

In this paper, optimal homotopy asymptotic method has been extended to seek out the exact solution of fractional generalized biological population models. The time fractional derivatives are described in the Caputo sense. It optimal homotopy asymptotic method is a new approach for fractional models. The proposed approach presents a procedure by that we have transferred the model to a series of simpler problems which are solvable by hand work applying the Riemann-Liouville fractional integral operator and obtained exact solution of fractional the generalized biological population by adding the solutions of first three simple problems of the series of simpler problems. The new approach provides exact solution in the way of smoothly convergent series.
Acupuncture, autonomic nervous system and biophysical origin of acupuncture system
Authors: Matic Zoran , Bojic Tijana
Published: January 2018

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Brain arteriovenous malformations
Authors: Stojanovic Sanja , Spasic Aleksandar , Basta-Nikolic Marijana , Kostic Dejan , Karac Mirjana , Turkalj Ivan
Published: January 2018

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Da pronúncia das políticas à efetivação do direito: a condição humana em debate
Authors: Lima Paulo Gomes
Published: January 2018

O debate aberto no volume 4, número 1 de 2018 da Laplage em Laplage em Revista organizado pelos Professores doutores Viviane Melo de Mendonça e Márcio Antônio Gatti, ambos do Departamento de Ciências Humanas e Educação do campus Sorocaba da UFSCar, é atual e repleto de pontuações concernentes à condição humana que se autoproduz e produz suas convenções, a ideia de valor e direitos validados ou não em políticas públicas. O tema trabalhado nesse Dossiê por autores de distintas instituições do Brasil e “overseas” não trata somente das políticas já existentes, de sua operância ou o contrário,  não trata somente da necessidade do anúncio e consolidação de novas políticas ou a readequação das já existentes quanto ao(s) direito(s) das pessoas serem respeitadas em sua dignidade, mas e sobretudo de colocar em evidência as vozes e ressignificações de seres humanos historicamente ignorados ou rechaçados no contexto de sua diversidade e singularidade, sem que se tornem menos cidadãos como os demais.
Socio-economic and cultural aspects of migration in the light of contemporary problems
Authors: Majchrzak Magdalena , Nikołajew Jan , Urbas Michał , Wulbach Elżbieta
Published: January 2018

Migration as a social phenomenon is a subject of interest to many disciplines. The fundamental question is: in which categories do we perceive the current wave of immigration in Europe. Perhaps it is a permanent migration crisis, as well in the social as in the the economic dimension or perhaps it is only a conjunctural issue. Part of European countries calculates that along with immigrants new jobs will appear, it will result in economic revival. It means that immigrants can stimulate economic but also cultural development. Therefore, you should "take a look" at the process of the migration in the micro and the macro scale. Taking into account this point of view, you should also analyze the phenomenon of contemporary migration in the multicultural context and through the adaptation processes. In their new social environment they will have to function without triggering hostility and aggression. The process of socio-professional adaptation is long and therefore it will force curren monitoring of the social and economic sciences.