bluuebunny/crossref_metadata_2025 huggingface dataset:
Figure S5 from Androgen Receptor Signaling Reduces the Efficacy of Bacillus Calmette-Guérin Therapy for Bladder Cancer via Modulating Rab27b-Induced Exocytosis
Authors: Mizushima Taichi , Jiang Guiyang , Kawahara Takashi , Li Peng , Han Bin , Inoue Satoshi , Ide Hiroki , Kato Ikuma , Jalalizadeh Mehrsa , Miyagi Etsuko , Fukuda Mitsunori , Reis Leonardo O. , Miyamoto Hiroshi
Published: April 2023

Effects of Rab27b overexpression on BCG cytotoxicity in bladder cancer cells.
Figure S3 from Androgen Receptor Signaling Reduces the Efficacy of Bacillus Calmette-Guérin Therapy for Bladder Cancer via Modulating Rab27b-Induced Exocytosis
Authors: Mizushima Taichi , Jiang Guiyang , Kawahara Takashi , Li Peng , Han Bin , Inoue Satoshi , Ide Hiroki , Kato Ikuma , Jalalizadeh Mehrsa , Miyagi Etsuko , Fukuda Mitsunori , Reis Leonardo O. , Miyamoto Hiroshi
Published: April 2023

Effects of Rab27b knockdown or overexpression on BCG cytotoxicity in bladder cancer cells.
Table S1 from An Orally Available Tubulin Inhibitor, VERU-111, Suppresses Triple-Negative Breast Cancer Tumor Growth and Metastasis and Bypasses Taxane Resistance
Authors: Deng Shanshan , Krutilina Raisa I. , Wang Qinghui , Lin Zongtao , Parke Deanna N. , Playa Hilaire C. , Chen Hao , Miller Duane D. , Seagroves Tiffany N. , Li Wei
Published: April 2023

Table S1 shows anti-proliferating effects of VERU-111 against various human cancer cell lines (mean {plus minus} SEM, n = 4 biological replicate experiments).
Figure S1 from Androgen Receptor Signaling Reduces the Efficacy of Bacillus Calmette-Guérin Therapy for Bladder Cancer via Modulating Rab27b-Induced Exocytosis
Authors: Mizushima Taichi , Jiang Guiyang , Kawahara Takashi , Li Peng , Han Bin , Inoue Satoshi , Ide Hiroki , Kato Ikuma , Jalalizadeh Mehrsa , Miyagi Etsuko , Fukuda Mitsunori , Reis Leonardo O. , Miyamoto Hiroshi
Published: April 2023

Immunofluorescence of BCG in bladder cancer cells.
Supplementary Table 4 from The HPV and p63 Status in Penile Cancer Are Linked with the Infiltration and Therapeutic Availability of Neutrophils
Authors: Bernhard Muriel Charlotte , Zwick Anabel , Mohr Tobias , Gasparoni Gilles , Khalmurzaev Oybek , Matveev Vsevolod Borisovich , Loertzer Philine , Pryalukhin Alexey , Hartmann Arndt , Geppert Carol-Immanuel , Loertzer Hagen , Wunderlich Heiko , Naumann Carsten Maik , Kalthoff Holger , Junker Kerstin , Smola Sigrun , Lohse Stefan
Published: April 2023

Supplementary Table 4
Figure S2 from EMP2 Is a Novel Regulator of Stemness in Breast Cancer Cells
Authors: Dillard Christen , Kiyohara Meagan , Mah Vei , McDermott Sean P. , Bazzoun Dana , Tsui Jessica , Chan Ann M. , Haddad Ghassan , Pellegrini Matteo , Chang Yu-Ling , Elshimali Yahya , Wu Yanyuan , Vadgama Jaydutt V. , Kim Sara R. , Goodglick Lee , Law Samuel M. , Patel Deven D. , Dhawan Puneet , O'Brien Neil A. , Gordon Lynn K. , Braun Jonathan , Lazar Gary , Wicha Max S. , Wadehra Madhuri
Published: April 2023

EMP2 and ALDH1 staining in breast cancer
Supplementary Table 3 from The HPV and p63 Status in Penile Cancer Are Linked with the Infiltration and Therapeutic Availability of Neutrophils
Authors: Bernhard Muriel Charlotte , Zwick Anabel , Mohr Tobias , Gasparoni Gilles , Khalmurzaev Oybek , Matveev Vsevolod Borisovich , Loertzer Philine , Pryalukhin Alexey , Hartmann Arndt , Geppert Carol-Immanuel , Loertzer Hagen , Wunderlich Heiko , Naumann Carsten Maik , Kalthoff Holger , Junker Kerstin , Smola Sigrun , Lohse Stefan
Published: April 2023

Supplementary Table 3
Figure S1 from EMP2 Is a Novel Regulator of Stemness in Breast Cancer Cells
Authors: Dillard Christen , Kiyohara Meagan , Mah Vei , McDermott Sean P. , Bazzoun Dana , Tsui Jessica , Chan Ann M. , Haddad Ghassan , Pellegrini Matteo , Chang Yu-Ling , Elshimali Yahya , Wu Yanyuan , Vadgama Jaydutt V. , Kim Sara R. , Goodglick Lee , Law Samuel M. , Patel Deven D. , Dhawan Puneet , O'Brien Neil A. , Gordon Lynn K. , Braun Jonathan , Lazar Gary , Wicha Max S. , Wadehra Madhuri
Published: April 2023

Modulation of EMP2 produces transcriptomic changes in breast cancer.
Supplementary Table 2 from The HPV and p63 Status in Penile Cancer Are Linked with the Infiltration and Therapeutic Availability of Neutrophils
Authors: Bernhard Muriel Charlotte , Zwick Anabel , Mohr Tobias , Gasparoni Gilles , Khalmurzaev Oybek , Matveev Vsevolod Borisovich , Loertzer Philine , Pryalukhin Alexey , Hartmann Arndt , Geppert Carol-Immanuel , Loertzer Hagen , Wunderlich Heiko , Naumann Carsten Maik , Kalthoff Holger , Junker Kerstin , Smola Sigrun , Lohse Stefan
Published: April 2023

Supplementary Table 2
Supplementary materials and methods from AZD0364 Is a Potent and Selective ERK1/2 Inhibitor That Enhances Antitumor Activity in KRAS-Mutant Tumor Models when Combined with the MEK Inhibitor, Selumetinib
Authors: Flemington Vikki , Davies Emma J. , Robinson David , Sandin Linda C. , Delpuech Oona , Zhang Pei , Hanson Lyndsey , Farrington Paul , Bell Sigourney , Falenta Katarzyna , Gibbons Francis D. , Lindsay Nicola , Smith Aaron , Wilson Joanne , Roberts Karen , Tonge Michael , Hopcroft Philip , Willis Sophie E. , Roudier Martine P. , Rooney Claire , Coker Elizabeth A. , Jaaks Patricia , Garnett Mathew J. , Fawell Stephen E. , Jones Clifford D. , Ward Richard A. , Simpson Iain , Cosulich Sabina C. , Pease J. Elizabeth , Smith Paul D.
Published: April 2023

Supplementary materials and methods
Supplementary Figure 2 from The HPV and p63 Status in Penile Cancer Are Linked with the Infiltration and Therapeutic Availability of Neutrophils
Authors: Bernhard Muriel Charlotte , Zwick Anabel , Mohr Tobias , Gasparoni Gilles , Khalmurzaev Oybek , Matveev Vsevolod Borisovich , Loertzer Philine , Pryalukhin Alexey , Hartmann Arndt , Geppert Carol-Immanuel , Loertzer Hagen , Wunderlich Heiko , Naumann Carsten Maik , Kalthoff Holger , Junker Kerstin , Smola Sigrun , Lohse Stefan
Published: April 2023

Supplementary Figure 2
Supplementary Table 3 from AZD0364 Is a Potent and Selective ERK1/2 Inhibitor That Enhances Antitumor Activity in KRAS-Mutant Tumor Models when Combined with the MEK Inhibitor, Selumetinib
Authors: Flemington Vikki , Davies Emma J. , Robinson David , Sandin Linda C. , Delpuech Oona , Zhang Pei , Hanson Lyndsey , Farrington Paul , Bell Sigourney , Falenta Katarzyna , Gibbons Francis D. , Lindsay Nicola , Smith Aaron , Wilson Joanne , Roberts Karen , Tonge Michael , Hopcroft Philip , Willis Sophie E. , Roudier Martine P. , Rooney Claire , Coker Elizabeth A. , Jaaks Patricia , Garnett Mathew J. , Fawell Stephen E. , Jones Clifford D. , Ward Richard A. , Simpson Iain , Cosulich Sabina C. , Pease J. Elizabeth , Smith Paul D.
Published: April 2023

Cell lines defined as sensitive to AZD0364 from 747 cell panel screen
Supplementary Figure 1 from The HPV and p63 Status in Penile Cancer Are Linked with the Infiltration and Therapeutic Availability of Neutrophils
Authors: Bernhard Muriel Charlotte , Zwick Anabel , Mohr Tobias , Gasparoni Gilles , Khalmurzaev Oybek , Matveev Vsevolod Borisovich , Loertzer Philine , Pryalukhin Alexey , Hartmann Arndt , Geppert Carol-Immanuel , Loertzer Hagen , Wunderlich Heiko , Naumann Carsten Maik , Kalthoff Holger , Junker Kerstin , Smola Sigrun , Lohse Stefan
Published: April 2023

Supplementary Figure 1
Supplementary Table 1 and Supplementary Figures 1-3 from Combinatorial Inhibition of Focal Adhesion Kinase and BCL-2 Enhances Antileukemia Activity of Venetoclax in Acute Myeloid Leukemia
Authors: Wang Xiangmeng , Mak Po Yee , Mu Hong , Tao Wenjing , Rao Arvind , Visweswaran Ravikumar , Ruvolo Vivian , Pachter Jonathan A. , Weaver David T. , Andreeff Michael , Xu Bing , Carter Bing Z.
Published: April 2023

Supplemental Table 1. Characteristics of AML patient samples used for the study. Supplemental Figure 1. PDX cells (mixed cells of the bone marrow and spleen), cultured alone or co-cultured with MSCs, were treated with VS-4718, ABT-199, or both. Annexin V/7AAD positivity was determined in human CD45+ cells by flow cytometry. COCX, co-cultured with MSCs. Supplemental Figure 2. Spleen sizes of the first, second, and fourth mice that died in the combination treatment group.
Table S1 from Predicting Tumor Killing and T-Cell Activation by T-Cell Bispecific Antibodies as a Function of Target Expression: Combining In Vitro Experiments with Systems Modeling
Authors: Van De Vyver Arthur J. , Weinzierl Tina , Eigenmann Miro J. , Frances Nicolas , Herter Sylvia , Buser Regula B. , Somandin Jitka , Diggelmann Sarah , Limani Florian , Lehr Thorsten , Bacac Marina , Walz Antje-Christine
Published: April 2023

Parameter description and units
Section S1 from Predicting Tumor Killing and T-Cell Activation by T-Cell Bispecific Antibodies as a Function of Target Expression: Combining In Vitro Experiments with Systems Modeling
Authors: Van De Vyver Arthur J. , Weinzierl Tina , Eigenmann Miro J. , Frances Nicolas , Herter Sylvia , Buser Regula B. , Somandin Jitka , Diggelmann Sarah , Limani Florian , Lehr Thorsten , Bacac Marina , Walz Antje-Christine
Published: April 2023

Supplementary section S1 describes the compound properties of cibisatamab as well as details on data generation, model development and modeling strategy applied
Figure S3 from Predicting Tumor Killing and T-Cell Activation by T-Cell Bispecific Antibodies as a Function of Target Expression: Combining In Vitro Experiments with Systems Modeling
Authors: Van De Vyver Arthur J. , Weinzierl Tina , Eigenmann Miro J. , Frances Nicolas , Herter Sylvia , Buser Regula B. , Somandin Jitka , Diggelmann Sarah , Limani Florian , Lehr Thorsten , Bacac Marina , Walz Antje-Christine
Published: April 2023

Dose-response profiles over time of various cytokines and T cell markers from assays with MNK45 and CX1 cell lines
Figure S8 from Pharmacologic Properties and Preclinical Activity of Sasanlimab, A High-affinity Engineered Anti-Human PD-1 Antibody
Authors: Al-Khami Amir A. , Youssef Sawsan , Abdiche Yasmina , Nguyen HoangKim , Chou Joyce , Kimberlin Christopher R. , Chin Sherman M. , Kamperschroer Cris , Jessen Bart , Kern Brent , Budimir Natalija , Dillon Christopher P. , Xu Allison , Clark Jerry D. , Chou Jeffrey , Kraynov Eugenia , Rajpal Arvind , Lin John C. , Salek-Ardakani Shahram
Published: April 2023

Supplementary Figure 8 shows the solution binding affinity of sasanlimab to human and cynomolgus monkey PD-1 using the KinExA
Supplementary Data from Development of Novel Antibody–Camptothecin Conjugates
Authors: Lyski Ryan D. , Bou Lauren B. , Lau Uland Y. , Meyer David W. , Cochran Julia H. , Okeley Nicole M. , Emmerton Kim K. , Zapata Francisco , Simmons Jessica K. , Trueblood Esther S. , Ortiz David J. , Zaval Margo C. , Snead Katie M. , Jin Steven , Farr Lauren M. , Ryan Maureen C. , Senter Peter D. , Jeffrey Scott C.
Published: April 2023

Table S1, Table S2, Table S3, Figure S1, Figure S2, Figure S3, Figure S4, Figure S5, Figure S6, Figure S7
Figure S6 from Pharmacologic Properties and Preclinical Activity of Sasanlimab, A High-affinity Engineered Anti-Human PD-1 Antibody
Authors: Al-Khami Amir A. , Youssef Sawsan , Abdiche Yasmina , Nguyen HoangKim , Chou Joyce , Kimberlin Christopher R. , Chin Sherman M. , Kamperschroer Cris , Jessen Bart , Kern Brent , Budimir Natalija , Dillon Christopher P. , Xu Allison , Clark Jerry D. , Chou Jeffrey , Kraynov Eugenia , Rajpal Arvind , Lin John C. , Salek-Ardakani Shahram
Published: April 2023

Supplementary Figure 6 shows the rCGE profile for sasanlimab with two predominant peaks, consistent with L chain and H chain
Figure S5 from Pharmacologic Properties and Preclinical Activity of Sasanlimab, A High-affinity Engineered Anti-Human PD-1 Antibody
Authors: Al-Khami Amir A. , Youssef Sawsan , Abdiche Yasmina , Nguyen HoangKim , Chou Joyce , Kimberlin Christopher R. , Chin Sherman M. , Kamperschroer Cris , Jessen Bart , Kern Brent , Budimir Natalija , Dillon Christopher P. , Xu Allison , Clark Jerry D. , Chou Jeffrey , Kraynov Eugenia , Rajpal Arvind , Lin John C. , Salek-Ardakani Shahram
Published: April 2023

Supplementary Figure 5 shows the analysis of sasanlimab by SE-HPLC with UV detection at 280 nm
Figure S4 from Pharmacologic Properties and Preclinical Activity of Sasanlimab, A High-affinity Engineered Anti-Human PD-1 Antibody
Authors: Al-Khami Amir A. , Youssef Sawsan , Abdiche Yasmina , Nguyen HoangKim , Chou Joyce , Kimberlin Christopher R. , Chin Sherman M. , Kamperschroer Cris , Jessen Bart , Kern Brent , Budimir Natalija , Dillon Christopher P. , Xu Allison , Clark Jerry D. , Chou Jeffrey , Kraynov Eugenia , Rajpal Arvind , Lin John C. , Salek-Ardakani Shahram
Published: April 2023

Supplementary Figure 4 shows the evaluation of the charge isoform distribution of sasanlimab by imaged capillary isoelectric focusing (iCE).
Supplementary Table S1 from A Novel Sulforaphane-Regulated Gene Network in Suppression of Breast Cancer–Induced Osteolytic Bone Resorption
Authors: Pore Subrata K. , Hahm Eun-Ryeong , Kim Su-Hyeong , Singh Krishna B. , Nyiranshuti Lea , Latoche Joseph D. , Anderson Carolyn J. , Adamik Juraj , Galson Deborah L. , Weiss Kurt R. , Watters Rebecca J. , Lee Boeun , Kumta Prashant N. , Singh Shivendra V.
Published: April 2023

Correlation between genes altered by SFN treatment (TCGA BrCa dataset, n = 1097).
Figure S16 from Pharmacologic Properties and Preclinical Activity of Sasanlimab, A High-affinity Engineered Anti-Human PD-1 Antibody
Authors: Al-Khami Amir A. , Youssef Sawsan , Abdiche Yasmina , Nguyen HoangKim , Chou Joyce , Kimberlin Christopher R. , Chin Sherman M. , Kamperschroer Cris , Jessen Bart , Kern Brent , Budimir Natalija , Dillon Christopher P. , Xu Allison , Clark Jerry D. , Chou Jeffrey , Kraynov Eugenia , Rajpal Arvind , Lin John C. , Salek-Ardakani Shahram
Published: April 2023

Supplementary Figure 16 shows the functional blockade of PD-1 receptors in cynomolgus monkeys treated with sasanlimab.
Supplementary Figure S3 from A Novel Sulforaphane-Regulated Gene Network in Suppression of Breast Cancer–Induced Osteolytic Bone Resorption
Authors: Pore Subrata K. , Hahm Eun-Ryeong , Kim Su-Hyeong , Singh Krishna B. , Nyiranshuti Lea , Latoche Joseph D. , Anderson Carolyn J. , Adamik Juraj , Galson Deborah L. , Weiss Kurt R. , Watters Rebecca J. , Lee Boeun , Kumta Prashant N. , Singh Shivendra V.
Published: April 2023

Expression of runt-related transcription factor 2 (RUNX2) protein in luminal-type breast cancers and normal mammary tissues.
Figure S14 from Pharmacologic Properties and Preclinical Activity of Sasanlimab, A High-affinity Engineered Anti-Human PD-1 Antibody
Authors: Al-Khami Amir A. , Youssef Sawsan , Abdiche Yasmina , Nguyen HoangKim , Chou Joyce , Kimberlin Christopher R. , Chin Sherman M. , Kamperschroer Cris , Jessen Bart , Kern Brent , Budimir Natalija , Dillon Christopher P. , Xu Allison , Clark Jerry D. , Chou Jeffrey , Kraynov Eugenia , Rajpal Arvind , Lin John C. , Salek-Ardakani Shahram
Published: April 2023

Supplementary Figure 14 shows that sasanlimab blocks the binding of human PD-1 to its ligands, PD-L1 and PD-L2, by SPR analysis.
Figure S13 from Pharmacologic Properties and Preclinical Activity of Sasanlimab, A High-affinity Engineered Anti-Human PD-1 Antibody
Authors: Al-Khami Amir A. , Youssef Sawsan , Abdiche Yasmina , Nguyen HoangKim , Chou Joyce , Kimberlin Christopher R. , Chin Sherman M. , Kamperschroer Cris , Jessen Bart , Kern Brent , Budimir Natalija , Dillon Christopher P. , Xu Allison , Clark Jerry D. , Chou Jeffrey , Kraynov Eugenia , Rajpal Arvind , Lin John C. , Salek-Ardakani Shahram
Published: April 2023

Supplementary Figure 13 shows the structure of sasanlimab bound to human PD-1: Final data collection and refinement statistics and exemplar electron density shown for the reported structure displaying the interface between sasanlimab light chain and hu-PD-1.
Supplementary Figure 4 from V-ATPase Inhibition Decreases Mutant Androgen Receptor Activity in Castrate-resistant Prostate Cancer
Authors: Whitton Bradleigh , Okamoto Haruko , Rose-Zerilli Matthew , Packham Graham , Crabb Simon J.
Published: April 2023

Figure S4 shows effect of enzalutamide on AR-F877L activation
Supplementary Data from Identification of Genes Required for Enzalutamide Resistance in Castration-Resistant Prostate Cancer Cells In Vitro
Authors: Kohrt Sarah E. , Awadallah Wisam N. , Phillips Robert A. , Case Thomas C. , Jin Renjie , Nanda Jagpreet S. , Yu Xiuping , Clark Peter E. , Yi Yajun , Matusik Robert J. , Anderson Philip D. , Grabowska Magdalena M.
Published: April 2023

Supplemental Methods
Supplementrary Figure 2 from DCLK1-Isoform2 Alternative Splice Variant Promotes Pancreatic Tumor Immunosuppressive M2-Macrophage Polarization
Authors: Chandrakesan Parthasarathy , Panneerselvam Janani , May Randal , Weygant Nathaniel , Qu Dongfeng , Berry William R. , Pitts Kamille , Stanger Ben Z. , Rao Chinthalapally V. , Bronze Michael S. , Houchen Courtney W.
Published: April 2023

DCLK1-isoform2 expression increased in PDAC. A) TSVdb webtool were utilized to analyze TCGA-PAAD dataset to identify the expression of different isoforms of DCLK1 in human pancreatic adenocarcinoma. B) DCLK1-isoform2 mRNA is highly expressed in pancreatic adenocarcinoma compared to adjacent solid pancreatic normal tissue in the TCGA-PAAD dataset analyzed from TSVdb webtool. DCLK1-isoform1 showed a marginal increase in pancreatic adenocarcinoma, whereas DCLK1-isoform 3&4 were not altered.
Supplementary Figure 5 from DCLK1-Isoform2 Alternative Splice Variant Promotes Pancreatic Tumor Immunosuppressive M2-Macrophage Polarization
Authors: Chandrakesan Parthasarathy , Panneerselvam Janani , May Randal , Weygant Nathaniel , Qu Dongfeng , Berry William R. , Pitts Kamille , Stanger Ben Z. , Rao Chinthalapally V. , Bronze Michael S. , Houchen Courtney W.
Published: April 2023

Correlation between the average number of Dclk1+ cells and M2 macrophages in the Dclk1 high and low PDAC. A. Fixed tumor tissues with CD8+ T-cell high (Dclk1 low) and CD8+ T-cell low (Dclk1 high) from an autochthonous mouse model of pancreatic adenocarcinoma were stained for Dclk1 and Arginase 1. Bar graph representing the average number of Dclk1+ cells and M2 macrophages in Dclk1 low and Dclk1 high expressing PDAC. Number of cells were quantified using ImageJ. All quantitative data are expressed as means {plus minus} SD and P values of <0.05Ã¢â,¬â€°=Ã¢â,¬â€°*, <0.01Ã¢â,¬â€°=Ã¢â,¬â€°**, and 0.001Ã¢â,¬â€°=Ã¢â,¬â€°*** were considered statistically significant.
Supplementary Figure 1 from DCLK1-Isoform2 Alternative Splice Variant Promotes Pancreatic Tumor Immunosuppressive M2-Macrophage Polarization
Authors: Chandrakesan Parthasarathy , Panneerselvam Janani , May Randal , Weygant Nathaniel , Qu Dongfeng , Berry William R. , Pitts Kamille , Stanger Ben Z. , Rao Chinthalapally V. , Bronze Michael S. , Houchen Courtney W.
Published: April 2023

DCLK1-isoforms. Graphical illustration demonstrating the length of each isoforms and shared protein kinase domain between DCLK1 isoforms referenced in UniProt; www.uniprot.org/uniprot/O15075. DCX1=Doublecortin1; DCX2=Doublecortin2; P/S=Pro/Ser rich domain.
Table S1 from Selective Inhibition of the Second Bromodomain of BET Family Proteins Results in Robust Antitumor Activity in Preclinical Models of Acute Myeloid Leukemia
Authors: Zhang Lu , Cai Tianyu , Lin Xiaoyu , Huang Xiaoli , Bui Mai H. , Plotnik Joshua P. , Bellin Richard J. , Faivre Emily J. , Kuruvilla Vinitha M. , Lam Lloyd T. , Lu Xin , Zha Zheng , Feng Weiguo , Hessler Paul , Uziel Tamar , Zhang Qi , Cavazos Antonio , Han Lina , Ferguson Debra C. , Mehta Gaurav , Shanmugavelandy Sriram S. , Magoc Terrance J. , Rowe Jenny , Goodwin Neal C. , Dorritie Kathleen A. , Boyiadzis Michael , Albert Daniel H. , McDaniel Keith F. , Kati Warren M. , Konopleva Marina , Shen Yu
Published: April 2023

Primary patient sample information
Figure S5 from Selective Inhibition of the Second Bromodomain of BET Family Proteins Results in Robust Antitumor Activity in Preclinical Models of Acute Myeloid Leukemia
Authors: Zhang Lu , Cai Tianyu , Lin Xiaoyu , Huang Xiaoli , Bui Mai H. , Plotnik Joshua P. , Bellin Richard J. , Faivre Emily J. , Kuruvilla Vinitha M. , Lam Lloyd T. , Lu Xin , Zha Zheng , Feng Weiguo , Hessler Paul , Uziel Tamar , Zhang Qi , Cavazos Antonio , Han Lina , Ferguson Debra C. , Mehta Gaurav , Shanmugavelandy Sriram S. , Magoc Terrance J. , Rowe Jenny , Goodwin Neal C. , Dorritie Kathleen A. , Boyiadzis Michael , Albert Daniel H. , McDaniel Keith F. , Kati Warren M. , Konopleva Marina , Shen Yu
Published: April 2023

Figure S5.Antitumor activity of ABBV-744/venetoclax in AML xenograft model and AML primary samples
Figure S4 from Selective Inhibition of the Second Bromodomain of BET Family Proteins Results in Robust Antitumor Activity in Preclinical Models of Acute Myeloid Leukemia
Authors: Zhang Lu , Cai Tianyu , Lin Xiaoyu , Huang Xiaoli , Bui Mai H. , Plotnik Joshua P. , Bellin Richard J. , Faivre Emily J. , Kuruvilla Vinitha M. , Lam Lloyd T. , Lu Xin , Zha Zheng , Feng Weiguo , Hessler Paul , Uziel Tamar , Zhang Qi , Cavazos Antonio , Han Lina , Ferguson Debra C. , Mehta Gaurav , Shanmugavelandy Sriram S. , Magoc Terrance J. , Rowe Jenny , Goodwin Neal C. , Dorritie Kathleen A. , Boyiadzis Michael , Albert Daniel H. , McDaniel Keith F. , Kati Warren M. , Konopleva Marina , Shen Yu
Published: April 2023

Figure S4.ABBV-744 displaces BRD4 from regulatory regions of BCL2, BCL2L1 and RUNX1 in sensitive AML cells but not insensitive AML line.
Figure S3 from Selective Inhibition of the Second Bromodomain of BET Family Proteins Results in Robust Antitumor Activity in Preclinical Models of Acute Myeloid Leukemia
Authors: Zhang Lu , Cai Tianyu , Lin Xiaoyu , Huang Xiaoli , Bui Mai H. , Plotnik Joshua P. , Bellin Richard J. , Faivre Emily J. , Kuruvilla Vinitha M. , Lam Lloyd T. , Lu Xin , Zha Zheng , Feng Weiguo , Hessler Paul , Uziel Tamar , Zhang Qi , Cavazos Antonio , Han Lina , Ferguson Debra C. , Mehta Gaurav , Shanmugavelandy Sriram S. , Magoc Terrance J. , Rowe Jenny , Goodwin Neal C. , Dorritie Kathleen A. , Boyiadzis Michael , Albert Daniel H. , McDaniel Keith F. , Kati Warren M. , Konopleva Marina , Shen Yu
Published: April 2023

Figure S3.Comparison of ABBV-744 and GSK046 BD2 selective compounds.
Figure S2 from Selective Inhibition of the Second Bromodomain of BET Family Proteins Results in Robust Antitumor Activity in Preclinical Models of Acute Myeloid Leukemia
Authors: Zhang Lu , Cai Tianyu , Lin Xiaoyu , Huang Xiaoli , Bui Mai H. , Plotnik Joshua P. , Bellin Richard J. , Faivre Emily J. , Kuruvilla Vinitha M. , Lam Lloyd T. , Lu Xin , Zha Zheng , Feng Weiguo , Hessler Paul , Uziel Tamar , Zhang Qi , Cavazos Antonio , Han Lina , Ferguson Debra C. , Mehta Gaurav , Shanmugavelandy Sriram S. , Magoc Terrance J. , Rowe Jenny , Goodwin Neal C. , Dorritie Kathleen A. , Boyiadzis Michael , Albert Daniel H. , McDaniel Keith F. , Kati Warren M. , Konopleva Marina , Shen Yu
Published: April 2023

Figure S2. ABBV-744 retains strong transcription regulatory activities in AML cells and it did not alter the baseline expression of representative IFN-r or PMA responsive genes.
Figure S1 from Selective Inhibition of the Second Bromodomain of BET Family Proteins Results in Robust Antitumor Activity in Preclinical Models of Acute Myeloid Leukemia
Authors: Zhang Lu , Cai Tianyu , Lin Xiaoyu , Huang Xiaoli , Bui Mai H. , Plotnik Joshua P. , Bellin Richard J. , Faivre Emily J. , Kuruvilla Vinitha M. , Lam Lloyd T. , Lu Xin , Zha Zheng , Feng Weiguo , Hessler Paul , Uziel Tamar , Zhang Qi , Cavazos Antonio , Han Lina , Ferguson Debra C. , Mehta Gaurav , Shanmugavelandy Sriram S. , Magoc Terrance J. , Rowe Jenny , Goodwin Neal C. , Dorritie Kathleen A. , Boyiadzis Michael , Albert Daniel H. , McDaniel Keith F. , Kati Warren M. , Konopleva Marina , Shen Yu
Published: April 2023

Figure S1.ABBV-744 exhibits potent anti-proliferative activity against AML cells through cell cycle arrest and induction of apoptosis.
Supplementary File S1 from Targeting CDK4/6 Represents a Therapeutic Vulnerability in Acquired BRAF/MEK Inhibitor–Resistant Melanoma
Authors: Nassar Kelsey W. , Hintzsche Jennifer D. , Bagby Stacey M. , Espinoza Veronica , Langouët-Astrié Christophe , Amato Carol M. , Chimed Tugs-Saikhan , Fujita Mayumi , Robinson William , Tan Aik Choon , Schweppe Rebecca E.
Published: April 2023

WES MB1998 and MB2132
Supplementary Data from MP-Pt(IV): A MAOB-Sensitive Mitochondrial-Specific Prodrug for Treating Glioblastoma
Authors: Raghavan Sudhir , Baskin David S. , Sharpe Martyn A.
Published: April 2023

Supplementary Figures S1 to S5 Supplementary Table 1 Synthesis
Supplementary Data from Depatuxizumab Mafodotin (ABT-414)-induced Glioblastoma Cell Death Requires EGFR Overexpression, but not EGFRY1068 Phosphorylation
Authors: von Achenbach Caroline , Silginer Manuela , Blot Vincent , Weiss William A. , Weller Michael
Published: April 2023

Supplementary Material
Supplementary Figure S1 from A Novel Peptidylarginine Deiminase 4 (PAD4) Inhibitor BMS-P5 Blocks Formation of Neutrophil Extracellular Traps and Delays Progression of Multiple Myeloma
Authors: Li Marina , Lin Cindy , Deng Hui , Strnad Joann , Bernabei Luca , Vogl Dan T. , Burke James J. , Nefedova Yulia
Published: April 2023

Figure S1 shows that pharmacological inhibition of PAD4 prevents MM1.S cell-induced NETosis.
Supplementary Figure S4 from Statins Reduce Intratumor Cholesterol Affecting Adrenocortical Cancer Growth
Authors: Trotta Francesca , Avena Paola , Chimento Adele , Rago Vittoria , De Luca Arianna , Sculco Sara , Nocito Marta C. , Malivindi Rocco , Fallo Francesco , Pezzani Raffaele , Pilon Catia , Lasorsa Francesco M. , Barile Simona N. , Palmieri Luigi , Lerario Antonio M. , Pezzi Vincenzo , Casaburi Ivan , Sirianni Rosa
Published: April 2023

Supplementary Fig. S4 shows the apoptotic mechanism activated by statins in ACC cells
Supplementary Figure S3 from Statins Reduce Intratumor Cholesterol Affecting Adrenocortical Cancer Growth
Authors: Trotta Francesca , Avena Paola , Chimento Adele , Rago Vittoria , De Luca Arianna , Sculco Sara , Nocito Marta C. , Malivindi Rocco , Fallo Francesco , Pezzani Raffaele , Pilon Catia , Lasorsa Francesco M. , Barile Simona N. , Palmieri Luigi , Lerario Antonio M. , Pezzi Vincenzo , Casaburi Ivan , Sirianni Rosa
Published: April 2023

Supplementary Fig. S3 shows that mevalonate and estradiol prevent simvastatin inhibitory effects.
Supplementary Figure from (+)-JJ-74–138 is a Novel Noncompetitive Androgen Receptor Antagonist
Authors: Cole Ryan N. , Chen Wei , Pascal Laura E. , Nelson Joel B. , Wipf Peter , Wang Zhou
Published: April 2023

Supplementary Figure from (+)-JJ-74–138 is a Novel Noncompetitive Androgen Receptor Antagonist
Supplementary fig 2 from The Radiosensitizing Effect of AZD0530 in Glioblastoma and Glioblastoma Stem-Like Cells
Authors: Yun Hong Shik , Lee Jennifer , Kil Whoon Jong , Kramp Tamalee R. , Tofilon Philip J. , Camphausen Kevin
Published: April 2023

suppl fig 2
Supplementary Fig 1 from The Radiosensitizing Effect of AZD0530 in Glioblastoma and Glioblastoma Stem-Like Cells
Authors: Yun Hong Shik , Lee Jennifer , Kil Whoon Jong , Kramp Tamalee R. , Tofilon Philip J. , Camphausen Kevin
Published: April 2023

suppl fig 1
Supplementary Table from Individualized Prediction of Drug Response and Rational Combination Therapy in NSCLC Using Artificial Intelligence–Enabled Studies of Acute Phosphoproteomic Changes
Authors: Coker Elizabeth A. , Stewart Adam , Ozer Bugra , Minchom Anna , Pickard Lisa , Ruddle Ruth , Carreira Suzanne , Popat Sanjay , O'Brien Mary , Raynaud Florence , de Bono Johann , Al-Lazikani Bissan , Banerji Udai
Published: April 2023

Supplementary Table from Individualized Prediction of Drug Response and Rational Combination Therapy in NSCLC Using Artificial Intelligence–Enabled Studies of Acute Phosphoproteomic Changes
Fig. S2 from β-Catenin Attenuation Inhibits Tumor Growth and Promotes Differentiation in a BRAFV600E-Driven Thyroid Cancer Animal Model
Authors: Zou Minjing , BinEssa Huda A. , Al-Malki Yousif H. , Al-Yahya Suhad , Al-Alwan Monther , Al-Jammaz Ibrahim , Khabar Khalid S.A. , Almohanna Falah , Assiri Abdullah M. , Meyer Brian F. , Alzahrani Ali S. , Al-Mohanna Futwan A. , Shi Yufei
Published: April 2023

Fig. S2. Kdm4a expression in thyroid tumor samples and cell lines. Kdm4a expression was analyzed by RNA-Seq. in normal control thyroids, BVE-Ctnnb1wt (BVE) and BVE-Ctnnb1null thyroid tumors, and cell lines. * indicates statistically significant between normal and tumor samples or cell lines (p<0.01). Data are expressed as mean {plus minus} SEM.
Fig. S1 from β-Catenin Attenuation Inhibits Tumor Growth and Promotes Differentiation in a BRAFV600E-Driven Thyroid Cancer Animal Model
Authors: Zou Minjing , BinEssa Huda A. , Al-Malki Yousif H. , Al-Yahya Suhad , Al-Alwan Monther , Al-Jammaz Ibrahim , Khabar Khalid S.A. , Almohanna Falah , Assiri Abdullah M. , Meyer Brian F. , Alzahrani Ali S. , Al-Mohanna Futwan A. , Shi Yufei
Published: April 2023

Fig. S1. Up-regulation of thyroid hormone synthesis-related genes in the BVE-Ctnnb1null thyroid tumors. Data are expressed as fold changes between BVE-Ctnnb1null and BVE tumors.
Supplementary Figure from Individualized Prediction of Drug Response and Rational Combination Therapy in NSCLC Using Artificial Intelligence–Enabled Studies of Acute Phosphoproteomic Changes
Authors: Coker Elizabeth A. , Stewart Adam , Ozer Bugra , Minchom Anna , Pickard Lisa , Ruddle Ruth , Carreira Suzanne , Popat Sanjay , O'Brien Mary , Raynaud Florence , de Bono Johann , Al-Lazikani Bissan , Banerji Udai
Published: April 2023

Supplementary Figure from Individualized Prediction of Drug Response and Rational Combination Therapy in NSCLC Using Artificial Intelligence–Enabled Studies of Acute Phosphoproteomic Changes
Supplementary Data from Maximal Activation of Apoptosis Signaling by Cotargeting Antiapoptotic Proteins in BH3 Mimetic–Resistant AML and AML Stem Cells
Authors: Carter Bing Z. , Mak Po Yee , Tao Wenjing , Zhang Qi , Ruvolo Vivian , Kuruvilla Vinitha M. , Wang Xiangmeng , Mak Duncan H. , Battula Venkata L. , Konopleva Marina , Jabbour Elias J. , Hughes Paul E. , Chen Xiaoyue , Morrow Phuong K. , Andreeff Michael
Published: April 2023

Supplementary Data from Maximal Activation of Apoptosis Signaling by Cotargeting Antiapoptotic Proteins in BH3 Mimetic–Resistant AML and AML Stem Cells
Table S2 from PCA062, a P-cadherin Targeting Antibody–Drug Conjugate, Displays Potent Antitumor Activity Against P-cadherin–expressing Malignancies
Authors: Sheng Qing , D'Alessio Joseph A. , Menezes Daniel L. , Karim Christopher , Tang Yan , Tam Angela , Clark Suzanna , Ying Chi , Connor Anu , Mansfield Keith G. , Rondeau Jean-Michel , Ghoddusi Majid , Geyer Felipe C. , Gu Jane , McLaughlin Margaret E. , Newcombe Rick , Elliot GiNell , Tschantz William R. , Lehmann Sylvie , Fanton Christie P. , Miller Kathy , Huber Thomas , Rendahl Katherine G. , Jeffry Ursula , Pryer Nancy K. , Lees Emma , Kwon Paul , Abraham Judith A. , Damiano Jason S. , Abrams Tinya J.
Published: April 2023

Cell line sensitivity table
Supplementary Data from DS-7300a, a DNA Topoisomerase I Inhibitor, DXd-Based Antibody–Drug Conjugate Targeting B7-H3, Exerts Potent Antitumor Activities in Preclinical Models
Authors: Yamato Michiko , Hasegawa Jun , Maejima Takanori , Hattori Chiharu , Kumagai Kazuyoshi , Watanabe Akiko , Nishiya Yumi , Shibutani Tomoko , Aida Tetsuo , Hayakawa Ichiro , Nakada Takashi , Abe Yuki , Agatsuma Toshinori
Published: April 2023

Supplementary Data from DS-7300a, a DNA Topoisomerase I Inhibitor, DXd-Based Antibody–Drug Conjugate Targeting B7-H3, Exerts Potent Antitumor Activities in Preclinical Models
Supplementary Table 5 from Comparative Study on the Efficacy and Exposure of Molecular Target Agents in Non–small Cell Lung Cancer PDX Models with Driver Genetic Alterations
Authors: Jo Hitomi , Yagishita Shigehiro , Hayashi Yoshiharu , Ryu Shoraku , Suzuki Mikiko , Kohsaka Shinji , Ueno Toshihide , Matsumoto Yuji , Horinouchi Hidehito , Ohe Yuichiro , Watanabe Shun-ichi , Motoi Noriko , Yatabe Yasushi , Mano Hiroyuki , Takahashi Kazuhisa , Hamada Akinobu
Published: April 2023

Supplementary Table 5
Copy number alteration result
Supplementary Table 4 from Comparative Study on the Efficacy and Exposure of Molecular Target Agents in Non–small Cell Lung Cancer PDX Models with Driver Genetic Alterations
Authors: Jo Hitomi , Yagishita Shigehiro , Hayashi Yoshiharu , Ryu Shoraku , Suzuki Mikiko , Kohsaka Shinji , Ueno Toshihide , Matsumoto Yuji , Horinouchi Hidehito , Ohe Yuichiro , Watanabe Shun-ichi , Motoi Noriko , Yatabe Yasushi , Mano Hiroyuki , Takahashi Kazuhisa , Hamada Akinobu
Published: April 2023

Supplementary Table 4
Whole-exome sequencing result
Supplementary Tables from Combined Blockade of MEK and CDK4/6 Pathways Induces Senescence to Improve Survival in Pancreatic Ductal Adenocarcinoma
Authors: Willobee Brent A. , Gaidarski Alexander A. , Dosch Austin R. , Castellanos Jason A. , Dai Xizi , Mehra Siddharth , Messaggio Fanuel , Srinivasan Supriya , VanSaun Michael N. , Nagathihalli Nagaraj S. , Merchant Nipun B.
Published: April 2023

Supplementary Tables S1-S3
Supplementary Table 2 from Comparative Study on the Efficacy and Exposure of Molecular Target Agents in Non–small Cell Lung Cancer PDX Models with Driver Genetic Alterations
Authors: Jo Hitomi , Yagishita Shigehiro , Hayashi Yoshiharu , Ryu Shoraku , Suzuki Mikiko , Kohsaka Shinji , Ueno Toshihide , Matsumoto Yuji , Horinouchi Hidehito , Ohe Yuichiro , Watanabe Shun-ichi , Motoi Noriko , Yatabe Yasushi , Mano Hiroyuki , Takahashi Kazuhisa , Hamada Akinobu
Published: April 2023

Supplementary Table 2
Chromatograms of the testing drugs
Supplementary Data from Combined Blockade of MEK and CDK4/6 Pathways Induces Senescence to Improve Survival in Pancreatic Ductal Adenocarcinoma
Authors: Willobee Brent A. , Gaidarski Alexander A. , Dosch Austin R. , Castellanos Jason A. , Dai Xizi , Mehra Siddharth , Messaggio Fanuel , Srinivasan Supriya , VanSaun Michael N. , Nagathihalli Nagaraj S. , Merchant Nipun B.
Published: April 2023

Supplementary Figures
Supplementary Figure 2 from Comparative Study on the Efficacy and Exposure of Molecular Target Agents in Non–small Cell Lung Cancer PDX Models with Driver Genetic Alterations
Authors: Jo Hitomi , Yagishita Shigehiro , Hayashi Yoshiharu , Ryu Shoraku , Suzuki Mikiko , Kohsaka Shinji , Ueno Toshihide , Matsumoto Yuji , Horinouchi Hidehito , Ohe Yuichiro , Watanabe Shun-ichi , Motoi Noriko , Yatabe Yasushi , Mano Hiroyuki , Takahashi Kazuhisa , Hamada Akinobu
Published: April 2023

Supplementary Figure 2
Figure 2A shows HER2 immunostaining images of each passage of LC-005. The RNA expression levels of EGFR, ERBB2, ERBB3 and MET in each PDX are shown in Figure 2B.
Supplementary Figure from YM155 Induces DNA Damage and Cell Death in Anaplastic Thyroid Cancer Cells by Inhibiting DNA Topoisomerase IIα at the ATP-Binding Site
Authors: Mackay Ryan P. , Weinberger Paul M. , Copland John A. , Mahdavian Elahe , Xu Qinqin
Published: April 2023

Supplementary Figure from YM155 Induces DNA Damage and Cell Death in Anaplastic Thyroid Cancer Cells by Inhibiting DNA Topoisomerase IIα at the ATP-Binding Site
Supplementary Methods from Targeted Therapy to β3 Integrin Reduces Chemoresistance in Breast Cancer Bone Metastases
Authors: Fox Gregory C. , Su Xinming , Davis Jennifer L. , Xu Yalin , Kwakwa Kristin A. , Ross Michael H. , Fontana Francesca , Xiang Jingyu , Esser Alison K. , Cordell Elizabeth , Pagliai Kristen , Dang Ha X. , Sivapackiam Jothilingam , Stewart Sheila A. , Maher Christopher A. , Bakewell Suzanne J. , Fitzpatrick James A.J. , Sharma Vijay , Achilefu Samuel , Veis Deborah J. , Lanza Gregory M. , Weilbaecher Katherine N.
Published: April 2023

Additional details for methods and materials.
Supplementary Figure S6 from Targeted Therapy to β3 Integrin Reduces Chemoresistance in Breast Cancer Bone Metastases
Authors: Fox Gregory C. , Su Xinming , Davis Jennifer L. , Xu Yalin , Kwakwa Kristin A. , Ross Michael H. , Fontana Francesca , Xiang Jingyu , Esser Alison K. , Cordell Elizabeth , Pagliai Kristen , Dang Ha X. , Sivapackiam Jothilingam , Stewart Sheila A. , Maher Christopher A. , Bakewell Suzanne J. , Fitzpatrick James A.J. , Sharma Vijay , Achilefu Samuel , Veis Deborah J. , Lanza Gregory M. , Weilbaecher Katherine N.
Published: April 2023

Evaluation of cellular response to mTORC1 inhibition, BLI analysis of visceral metastases in PyMT-BO1 tumor-bearing mice receiving combination therapies, and αvβ3-NP-RAPA toxicity studies.
Supplementary Figure S2 from Targeted Therapy to β3 Integrin Reduces Chemoresistance in Breast Cancer Bone Metastases
Authors: Fox Gregory C. , Su Xinming , Davis Jennifer L. , Xu Yalin , Kwakwa Kristin A. , Ross Michael H. , Fontana Francesca , Xiang Jingyu , Esser Alison K. , Cordell Elizabeth , Pagliai Kristen , Dang Ha X. , Sivapackiam Jothilingam , Stewart Sheila A. , Maher Christopher A. , Bakewell Suzanne J. , Fitzpatrick James A.J. , Sharma Vijay , Achilefu Samuel , Veis Deborah J. , Lanza Gregory M. , Weilbaecher Katherine N.
Published: April 2023

Validation of Itgb3 CRISPR knockout in 4T1 and PyMT-BO1 cells and assessment of docetaxel sensitivity in vitro and in vivo.
Supplementary Figure S1 from Targeted Therapy to β3 Integrin Reduces Chemoresistance in Breast Cancer Bone Metastases
Authors: Fox Gregory C. , Su Xinming , Davis Jennifer L. , Xu Yalin , Kwakwa Kristin A. , Ross Michael H. , Fontana Francesca , Xiang Jingyu , Esser Alison K. , Cordell Elizabeth , Pagliai Kristen , Dang Ha X. , Sivapackiam Jothilingam , Stewart Sheila A. , Maher Christopher A. , Bakewell Suzanne J. , Fitzpatrick James A.J. , Sharma Vijay , Achilefu Samuel , Veis Deborah J. , Lanza Gregory M. , Weilbaecher Katherine N.
Published: April 2023

Flow cytometric analysis of integrin β3 staining on breast cancer cells.
Supplementary Table from Cyst(e)inase–Rapamycin Combination Induces Ferroptosis in Both In Vitro and In Vivo Models of Hereditary Leiomyomatosis and Renal Cell Cancer
Authors: Kerimoglu Baris , Lamb Candice , McPherson Ryan D. , Ergen Ergul , Stone Everett M. , Ooi Aikseng
Published: April 2023

Supplementary Table from Cyst(e)inase–Rapamycin Combination Induces Ferroptosis in Both In Vitro and In Vivo Models of Hereditary Leiomyomatosis and Renal Cell Cancer
Supplemental File 4 from EMT-Induced Gemcitabine Resistance in Pancreatic Cancer Involves the Functional Loss of Equilibrative Nucleoside Transporter 1
Authors: Weadick Brenna , Nayak Debasis , Persaud Avinash K. , Hung Sau Wai , Raj Radhika , Campbell Moray J. , Chen Wei , Li Junan , Williams Terence M. , Govindarajan Rajgopal
Published: April 2023

Video 4. E+/N- cells animation displays 3D reconstruction of ENT1 (red) and DAPI (blue)
Supplementary Data from Cyst(e)inase–Rapamycin Combination Induces Ferroptosis in Both In Vitro and In Vivo Models of Hereditary Leiomyomatosis and Renal Cell Cancer
Authors: Kerimoglu Baris , Lamb Candice , McPherson Ryan D. , Ergen Ergul , Stone Everett M. , Ooi Aikseng
Published: April 2023

Supplementary Data from Cyst(e)inase–Rapamycin Combination Induces Ferroptosis in Both In Vitro and In Vivo Models of Hereditary Leiomyomatosis and Renal Cell Cancer
Supplemental File 2 from EMT-Induced Gemcitabine Resistance in Pancreatic Cancer Involves the Functional Loss of Equilibrative Nucleoside Transporter 1
Authors: Weadick Brenna , Nayak Debasis , Persaud Avinash K. , Hung Sau Wai , Raj Radhika , Campbell Moray J. , Chen Wei , Li Junan , Williams Terence M. , Govindarajan Rajgopal
Published: April 2023

Video 2. Animation displays 3D reconstruction of PANC-1 cells grown in monolayer immunostained for ENT1 (red) and DAPI (blue)
Supplemental File 1 from EMT-Induced Gemcitabine Resistance in Pancreatic Cancer Involves the Functional Loss of Equilibrative Nucleoside Transporter 1
Authors: Weadick Brenna , Nayak Debasis , Persaud Avinash K. , Hung Sau Wai , Raj Radhika , Campbell Moray J. , Chen Wei , Li Junan , Williams Terence M. , Govindarajan Rajgopal
Published: April 2023

Video 1. PANC-1 cells stably overexpressing E-cadherin are shown in this animation of a 3D reconstruction of compiled z-stack images. ENT1 (red), E-cadherin (green), DAPI (blue).
Supplementary Table from A High-Throughput Screening Platform Identifies Novel Combination Treatments for Malignant Peripheral Nerve Sheath Tumors
Authors: Fernández-Rodríguez Juana , Creus-Bachiller Edgar , Zhang Xiaohu , Martínez-Iniesta Maria , Ortega-Bertran Sara , Guha Rajarshi , Thomas Craig J. , Wallace Margaret R. , Romagosa Cleofe , Salazar-Huayna Lourdes , Reilly Karlyne M. , Blakely Jaishri O. , Serra-Musach Jordi , Pujana Miguel Angel , Serra Eduard , Villanueva Alberto , Ferrer Marc , Lázaro Conxi
Published: April 2023

Supplementary Table from A High-Throughput Screening Platform Identifies Novel Combination Treatments for Malignant Peripheral Nerve Sheath Tumors
Supplementary Figure from Adoptive Transfer of Anti-Nucleolin T Cells Combined with PD-L1 Inhibition against Triple-Negative Breast Cancer
Authors: Thongchot Suyanee , Jirapongwattana Niphat , Luangwattananun Piriya , Chiraphapphaiboon Wannasiri , Chuangchot Nisa , Sa-nguanraksa Doonyapat , O-Charoenrat Pornchai , Thuwajit Peti , Yenchitsomanus Pa-thai , Thuwajit Chanitra
Published: April 2023

Supplementary Figure from Adoptive Transfer of Anti-Nucleolin T Cells Combined with PD-L1 Inhibition against Triple-Negative Breast Cancer
Supplementary Data from Growth Inhibition and Induction of Innate Immune Signaling of Chondrosarcomas with Epigenetic Inhibitors
Authors: Sheikh Tahir N. , Chen Xiao , Xu Xinjing , McGuire John T. , Ingham Matthew , Lu Chao , Schwartz Gary K.
Published: April 2023

Contains Figure S1-S6; Table S1-S2
Supplementary Data from Adoptive Transfer of Anti-Nucleolin T Cells Combined with PD-L1 Inhibition against Triple-Negative Breast Cancer
Authors: Thongchot Suyanee , Jirapongwattana Niphat , Luangwattananun Piriya , Chiraphapphaiboon Wannasiri , Chuangchot Nisa , Sa-nguanraksa Doonyapat , O-Charoenrat Pornchai , Thuwajit Peti , Yenchitsomanus Pa-thai , Thuwajit Chanitra
Published: April 2023

Supplementary Data from Adoptive Transfer of Anti-Nucleolin T Cells Combined with PD-L1 Inhibition against Triple-Negative Breast Cancer
Supplementary Data from 89Zr-ImmunoPET Shows Therapeutic Efficacy of Anti-CD20-IFNα Fusion Protein in a Murine B-cell Lymphoma Model
Authors: Zettlitz Kirstin A. , Salazar Felix B. , Yamada Reiko E. , Trinh K. Ryan , Vasuthasawat Alex , Timmerman John M. , Morrison Sherie L. , Wu Anna M.
Published: April 2023

Supplementary Data from 89Zr-ImmunoPET Shows Therapeutic Efficacy of Anti-CD20-IFNα Fusion Protein in a Murine B-cell Lymphoma Model
Video S2B from Harnessing the hERG1/β1 Integrin Complex via a Novel Bispecific Single-chain Antibody: An Effective Strategy against Solid Cancers
Authors: Duranti Claudia , Iorio Jessica , Lottini Tiziano , Lastraioli Elena , Crescioli Silvia , Bagni Giacomo , Lulli Matteo , Capitani Chiara , Bouazzi Rayhana , Stefanini Matteo , Carraresi Laura , Iamele Luisa , De Jonge Hugo , Arcangeli Annarosa
Published: April 2023

Non Linear Contrast Mode imaging of mouse kidneys 3 hours after the injection of 8mg/kg of scDb
Supplementary Data from Targeting TfR1 with the ch128.1/IgG1 Antibody Inhibits EBV-driven Lymphomagenesis in Immunosuppressed Mice Bearing EBV+ Human Primary B-cells
Authors: Martínez Laura E. , Daniels-Wells Tracy R. , Guo Yu , Magpantay Larry I. , Candelaria Pierre V. , Penichet Manuel L. , Martínez-Maza Otoniel , Epeldegui Marta
Published: April 2023

Figure S1 , Figure S2
Supplementary Tables from Radiosensitizing Pancreatic Cancer via Effective Autophagy Inhibition
Authors: Yazal Taha , Bailleul Justine , Ruan Yangjingyi , Sung David , Chu Fang-I , Palomera Daisy , Dao Amy , Sehgal Anahita , Gurunathan Vibha , Aryan Laila , Eghbali Mansoureh , Vlashi Erina
Published: April 2023

Supplementary Tables show supplementary tables 1 to 5.
Supplementary Fig. 6 from Radiosensitizing Pancreatic Cancer via Effective Autophagy Inhibition
Authors: Yazal Taha , Bailleul Justine , Ruan Yangjingyi , Sung David , Chu Fang-I , Palomera Daisy , Dao Amy , Sehgal Anahita , Gurunathan Vibha , Aryan Laila , Eghbali Mansoureh , Vlashi Erina
Published: April 2023

Supplementary Figure S6 shows mice weights, tumor volumes, statistical analysis, LC3 immunohistochemistry images and LC3 quantification in tumor sections.
Video S1D from Harnessing the hERG1/β1 Integrin Complex via a Novel Bispecific Single-chain Antibody: An Effective Strategy against Solid Cancers
Authors: Duranti Claudia , Iorio Jessica , Lottini Tiziano , Lastraioli Elena , Crescioli Silvia , Bagni Giacomo , Lulli Matteo , Capitani Chiara , Bouazzi Rayhana , Stefanini Matteo , Carraresi Laura , Iamele Luisa , De Jonge Hugo , Arcangeli Annarosa
Published: April 2023

Non Linear Contrast Mode imaging of mouse kidneys 3 hours after the injection of saline solution (CTRL)
Supplementary Fig. 3 from Radiosensitizing Pancreatic Cancer via Effective Autophagy Inhibition
Authors: Yazal Taha , Bailleul Justine , Ruan Yangjingyi , Sung David , Chu Fang-I , Palomera Daisy , Dao Amy , Sehgal Anahita , Gurunathan Vibha , Aryan Laila , Eghbali Mansoureh , Vlashi Erina
Published: April 2023

Supplementary Figure S3 shows ATP-lite assays and EC50 for HCQ and EAD1.
Supplementary Fig. 1 from Radiosensitizing Pancreatic Cancer via Effective Autophagy Inhibition
Authors: Yazal Taha , Bailleul Justine , Ruan Yangjingyi , Sung David , Chu Fang-I , Palomera Daisy , Dao Amy , Sehgal Anahita , Gurunathan Vibha , Aryan Laila , Eghbali Mansoureh , Vlashi Erina
Published: April 2023

Supplementary Figure S1 shows LC3/p62 flow histograms, confocal images of LC3 puncta and LC3 puncta quantification.
Supplementary Methods from A Benzenesulfonamide-Based Mitochondrial Uncoupler Induces Endoplasmic Reticulum Stress and Immunogenic Cell Death in Epithelial Ovarian Cancer
Authors: Bi Fangfang , Jiang Ziyan , Park Wonmin , Hartwich Tobias M.P. , Ge Zhiping , Chong Kay Y. , Yang Kevin , Morrison Madeline J. , Kim Dongin , Kim Jaeyeon , Zhang Wen , Kril Liliia M. , Watt David S. , Liu Chunming , Yang-Hartwich Yang
Published: April 2023

Supplementary Information
Supplementary Table T1 from F-aza-T-dCyd (NSC801845), a Novel Cytidine Analog, in Comparative Cell Culture and Xenograft Studies with the Clinical Candidates T-dCyd, F-T-dCyd, and Aza-T-dCyd
Authors: Morris Joel , Wishka Donn G. , Lopez Omar D. , Rudchenko Vladimir , Huang Guangfei , Hoffman Sierra N. , Borgel Suzanne , Georgius Kyle , Carter John , Stotler Howard , Kunkel Mark W. , Collins Jerry M. , Hollingshead Melinda G. , Teicher Beverly A.
Published: April 2023

Supplementary Table T1
Supplementary Figure S1 from F-aza-T-dCyd (NSC801845), a Novel Cytidine Analog, in Comparative Cell Culture and Xenograft Studies with the Clinical Candidates T-dCyd, F-T-dCyd, and Aza-T-dCyd
Authors: Morris Joel , Wishka Donn G. , Lopez Omar D. , Rudchenko Vladimir , Huang Guangfei , Hoffman Sierra N. , Borgel Suzanne , Georgius Kyle , Carter John , Stotler Howard , Kunkel Mark W. , Collins Jerry M. , Hollingshead Melinda G. , Teicher Beverly A.
Published: April 2023

Supplementary Figure S1
Video S1A from Harnessing the hERG1/β1 Integrin Complex via a Novel Bispecific Single-chain Antibody: An Effective Strategy against Solid Cancers
Authors: Duranti Claudia , Iorio Jessica , Lottini Tiziano , Lastraioli Elena , Crescioli Silvia , Bagni Giacomo , Lulli Matteo , Capitani Chiara , Bouazzi Rayhana , Stefanini Matteo , Carraresi Laura , Iamele Luisa , De Jonge Hugo , Arcangeli Annarosa
Published: April 2023

Non Linear Contrast Mode imaging of mouse kidneys 3 hours after the injection of saline solution (CTRL)