bluuebunny/crossref_metadata_2025 huggingface dataset:
PURSUING HIGHER EDUCATION CAREERS AND THE PROCESS OF MIGRATION AMONG INDONESIAN FEMALE MIGRANT WORKERS IN TAIWAN
Authors: Bali Sandrotua , Chou Liu Ming , Hsuan Lin Huei
Published: December 2019

Remittance, labor migration and the significance of the female role in the process of labor migration have recently become entrenched in many developing countries, such as Indonesia. The influential role these female migrant workers play in supporting their own families and in their self-fulfillment is of significance and worthy of being fully expounded and discussed. As breadwinners, these female migrant workers strive to pursue higher education by working their way through college. Qualitative in-depth interviews and focus group discussions were used to obtain five Indonesian female migrant workers' opinion and experiences about their experience of being a worker and a student in Taiwan. The data in this study were analyzed and evaluated with thematic analysis. This study describes the factors which cause the Indonesian female workers to become migrant workers in Taiwan. This includes getting high-paid jobs, shouldering the responsibility for supporting their own families, and pursuing self-fulfillment overseas. Besides, this study has investigated the difficulties and challenges that female Indonesian migrant workers had encountered while working and studying at the same time. On the whole, as caregivers, most of them often fail to have a flexible schedule to study due to the temporary jobs assigned by their employers. Also, some employers are unwilling to allow them to pursue higher education for feat that they would not concentrate on their own work. Above all, it is these female migrant workers that can define what their lives truly mean as migrant workers on their own, and that can align their talents and ambitions with their pursuits of higher education. This study provides a new exploration of how the female migrant workers’ gained a sense of self-fulfillment by pursuing higher education with working and studying at the same time. Facing a variety of challenges and hindrances, their persistence and perseverance can be further examined for those who are interested in studying this field deeper.
 
Keywords: Female migrant workers, higher education, Indonesian migrant workers, labor migration, remittance
 
Cite as: Bali, S., Liu, M. C., & Lin, H. H. (2019). Pursuing higher education careers and the process of migration among Indonesian female migrant workers in Taiwan.  Journal of Nusantara Studies, 4(2), 302-317. http://dx.doi.org/10.24200/jonus.vol4iss2pp302-317
Efecto mediador de la motivación autónoma en el aprendizaje
Authors: Vergara-Morales Jorge , Del Valle Tapia Milenko , Díaz Mujica Alejandro , Matos Fernández Lennia , Pérez Villalobos María Victoria
Published: December 2019

Las investigaciones destacan la necesidad de indagar los mecanismos psicológicos que intervienen en el desarrollo de los aprendizajes en el aula. El objetivo del estudio fue evaluar el rol mediador de los tipos de regulación que componen la motivación autónoma, en la relación entre percepción de apoyo a la autonomía, satisfacción académica y desempeño académico percibido por estudiantes universitarios. Los participantes fueron 229 estudiantes de primer año de cuatro universidades chilenas. El efecto mediador se evaluó utilizando el macro PROCESS para SPSS. Los resultados indicaron que tanto la regulación intrínseca como la regulación identificada intervienen parcialmente el efecto de la percepción de apoyo a la autonomía sobre la satisfacción académica, pero sólo la regulación intrínseca interviene totalmente el efecto sobre el desempeño académico. Se concluye que los tipos de regulación autónoma constituyen mecanismos a través de los cuales se influye positivamente en el bienestar y logro académico de estudiantes universitarios.
Above and Below Ground Biomass and Carbon Stock in Permanent Grasslands of Slovakia
Authors: Kizeková Miriam , Kanianska Radoslava , Jančová Ľubica , Čunderlík Jozef , Dugátová Zuzana , Makovníková Jarmila
Published: December 2019

This paper aimed to monitory the dry matter biomass production and carbon stocks of above-and below-ground biomass in five types of grasslands in Slovakia: i) lowland oversowed pasture ii) lowland hay meadows, iii) mesophilous pasture, iv) mountain hay meadows, v) abandoned grassland. Averaged over two cropping seasons the total above-and below-ground biomass differed significantly across the monitored grasslands. It ranged respectively from 2.18 to 7.86 t/ha and from 9.64 to 22.67 t/ha dry matter depending on the pedoclimatic condition and the botanical composition of each grassland type. Consequently, this resulted also in the carbon stocks in above-and below-ground biomass. Generally, the mean carbon stocks were 1.56 t/ha for above-ground biomass (24%) and 4.83 t/ha for below-ground biomass (76%). The botanical composition for all the grassland types was also described. The highest number of plant species (55) was observed in lowland hay meadow located in Slovak Karst, the lowest one (23) for the oversowed grassland located in Eastern Slovak Upland. This monitoring paper showed that semi-natural grassland habitats and improved grasslands as well are an important carbon sink, and they can play a key role in global climate change mitigation.
Sorption Capacity of Sandy Soil Under Long-Term Fertilisation
Authors: Šimanský Vladimír , Jonczak Jerzy
Published: December 2019

In this paper, the results of an investigation of the effects of particle-size distribution, soil organic matter content and its parameters on soil sorption capacity are presented and their mutual relationships in sandy soils under long-term fertilisation experiments are determined. Soil samples were taken at the experimental station of Warsaw University of Life Sciences located in Skierniewice, (Poland) in spring 2017. The study included 94- and 41-year-old experiments with mineral fertilisation (no fertilisation, NPK, CaNPK) and 25-year-old experiment with mineral fertilisation + farmyard manure (FYM) in 4-year cycle: FYM, FYM+NPK and FYM+CaNPK. The results show that in the 94-year-old experiment in NPK and CaNPK treatments, hydrolytic acidity (Ha) decreased in comparison with the control by 30% and 88%, respectively, while in 25- and 41-year-old experiments only the application of NPK significantly increased Ha values. The sum of basic cations increased by a factor of 10 at the most in the CaNPK treatment in the 94-year-old experiment. The same effect was also observed in the 25-year-old experiment. On the one hand, the sorption complex gradually became fully saturated as a result of fertilisation in the 94-year-old experiment. On the other hand, in the 25- and 41-year-old experiments, base saturation was substantially reduced. A higher humus stability was an important agent for improving soil sorption capacity in 41- and 94-year old experiments.
Comparative Study of Stabilization Controls of a Forklift Vehicle
Authors: Widyotriatmo Augie
Published: December 2019

This paper presents the control designs for an autonomous forklift vehicle that drive the vehicle from an initial configuration to a final one. Three stabilization controls, which are chained-form time-varying control, sigma-transformed discontinuous control, and navigation-variables-based discontinuous control, for a forklift vehicle are compared by simulations. The sigma-transformed and navigation-variables-based discontinuous controls provide fast convergence motions from an initial to a final configuration, while the time-varying-based control provides oscillatory motion and slow convergence. The sigma-transformed discontinuous control has a set of discontinuous points in which, from a practical point of view, the control signals can blow up if a vehicle enters the set. The navigation-variables-based control, which also has a discontinuous point at the final configuration, does not produce blown up control signals since its boundedness nature. Discussion on the implementation of control algorithm is elucidated for the three stabilization controls for the forklift vehicle.
Attribute Selection for Stroke Prediction
Authors: Zdrodowska Małgorzata
Published: December 2019

Stroke is the third most common cause of death and the most common cause of long-term disability among adults around theworld. Therefore, stroke prediction and diagnosis is a very important issue. Data mining techniques come in handy to help determine the correlations between individual patient characterisation data, that is, extract from the medical information system the knowledge necessary to predict and treat various diseases. The study analysed the data of patients with stroke using eight known classification algorithms (J48 (C4.5), CART, PART, naive Bayes classifier, Random Forest, Supporting Vector Machine and neural networks Multilayer Perceptron), which allowed to build an exploration model given with an accuracy of over 88%. The potential features of patients, which may be factors that increase the risk of stroke, were also indicated.
Near-Surface Mass Defect in Models of Locally Heterogeneous Solid Mechanics
Authors: Nahirnyj Taras , Tchervinka Kostiantyn
Published: December 2019

This article deals with the model of the locally heterogeneous elastic body. The model accounts for long-range interaction and describes near-surface non-homogeneity and related size effects. The key systems of model equations are presented. From the viewpoint of the representative volume element, the boundary condition for density and the limits of applicability of the model are discussed. The difference of mass density in the near-surface body region from the reference value (near-surface mass defect) causes a non-zero stressed state. It is indicated on the strong dependence of the surface value of density from the curvature of the surface of thin fibres. The effect of the near-surface mass defect on the stressed state and the size effect of surface stresses have been investigated on an example of a hollow cylinder. Size effect of its strength has been studied as well.
Pick-and-Place Task Implementation Using Visual Open-Loop Control
Authors: Kołosowski Paweł , Wolniakowski Adam , Bogdan Mariusz
Published: December 2019

In the ever increasing number of robotic system applications in the industry, the robust and fast visual recognition and pose estimation of workpieces are of utmost importance. One of the ubiquitous tasks in industrial settings is the pick-and-place task where the object recognition is often important. In this paper, we present a new implementation of a work-piece sorting system using a template matching method for recognizing and estimating the position of planar workpieces with sparse visual features. The proposed framework is able to distinguish between the types of objects presented by the user and control a serial manipulator equipped with parallel finger gripper to grasp and sort them automatically. The system is furthermore enhanced with a feature that optimizes the visual processing time by automatically adjusting the template scales. We test the proposed system in a real-world setup equipped with a UR5 manipulator and provide experimental results documenting the performance of our approach.
Analyzing passing networks in association football based on the difficulty, risk, and potential of passes
Authors: Wiig A.S. , Håland E.M. , Stålhane M. , Hvattum L.M.
Published: December 2019

This paper investigates the use of network analysis to identify key players on teams, and patterns of passing within teams, in association football. Networks are constructed based on passes made between players, and several centrality measures are investigated in combination with three different methods for evaluating individual passes. Four seasons of data from the Norwegian top division are used to identify key players and analyze matches from a selected team. The networks examined in this work have weights based on three different aspects of the passes made: their probability of being completed, the probability that the team keeps possession after the completed pass, and the probability of the pass being part of a sequence leading to a shot. The results show that using different metrics and network weights leads to the identification of key passers in different phases of play and in different positions on the pitch.
Assessing the causal impact of the 3-point per victory scoring system in the competitive balance of LaLiga
Authors: Soto-Valero C , Pic M.
Published: December 2019

Competitive balance is a key concept in sport because it creates an uncertainty on the outcome that leads to increased interest and demand for these events. The Spanish Professional Football League (LaLiga) has been one of the top European leagues in the last decade, and it has given rise to a particular research interest regarding its characteristics and structure. Since season 1995/96, LaLiga changed the number of points given to the winning teams, by awarding three points per victory instead of two. In this paper, we assess the impact of such a change on the competitive balance of LaLiga. Our analysis focuses on teams with varying levels of performance and follows a three-step approach. First, we cluster the teams according to their historical performance using an adjusted measure based on their credible intervals of winning ratios. Second, we calculate Kendall’s tau coefficient (according to our adjusted measure) in order to obtain the overall ranking turnover of teams between consecutive seasons. Third, we assess the causal impact of the adoption of the new scoring system, based on Kendall’s tau coefficients, for each cluster of teams. Our results show that the overall competitive balance decreased after the adoption of the new scoring system. However, the impact was not the same for all teams, being more significant for top teams and less significant for bottom teams. Moreover, our predictions using adjusted ARIMA models indicate that this difference in the competitive balance will persist for future seasons.
The effects of age and body weight on powerlifters: An analysis model of powerlifting performance based on machine learning
Authors: Chau Vinh Huy , Vo Anh Thu , Le Ba Tuan
Published: December 2019

As a up and coming sport, powerlifting is gathering more and more attetion. Powerlifters vary in their strength levels and performances at different ages as well as differing in height and weight. Hence the questions arises on how to establish the relationship between age and weight. It is difficult to judge the performance of athletes by artificial expertise, as subjective factors affecting the performance of powerlifters often fail to achieve the desired results. In recent years, artificial intelligence has made groundbreaking strides. Therefore, using artificial intelligence to predict the performance of athletes is among one of many interesting topics in sports competitions. Based on the artificial intelligence algorithm, this research proposes an analysis model of powerlifters’ performance. The results show that the method proposed in this paper can predict the best performance of powerlifters. Coefficient of determination-R2=0.86 and root-mean-square error of prediction-RMSEP=20.98 demonstrate the effectiveness of our method.
Photoluminescence and piezoelectricity investigation of La1.98Nd0.02Ti2O7, Sm1.98Ce0.02Ti2O7 and Er1.98Gd0.02Ti2O7 multifunctional materials
Authors: Öztürk Esra , Sarilmaz Ebru
Published: December 2019

Nd3+ doped La2Ti2O7, Ce4+ doped Sm2Ti2O7 and Gd3+ doped Er2Ti2O7 have been synthesized at different reaction temperatures using solid state reaction method, and characterized using X-ray diffraction (XRD), scanning electron microscopy (SEM), differential thermal analysis (DTA), thermogravimetric analysis (TG). Excitation spectra, emission spectra and decay time curves of the samples were investigated by photoluminescence spectrophotometer (PL) and typical transitions of rare earth ions were observed. Dielectric properties, piezoelectric properties and Curie temperature of the obtained luminescent materials were measured for electrical characterization. The results showed that all materials have both photoluminescent and piezoelectric properties and show high Curie temperature.
Migration and wintering of Fieldfare (Turdus pilaris) in southeastern Hungary
Authors: Bozó László
Published: December 2019

The Fieldfare is a bird species widely distributed in the Palearctic region. In Hungary, the species is considered as a rare breeder and common, sometimes abundant migrant in autumn and spring, and also as winter visitor. It is prone to invasion, since northern breeding populations leave the breeding sites in large numbers only when the available food is inadequate or inaccessible to the birds. Most populations follow a southern-southwestern migration pattern, and in the course of their movement they also migrating through the Carpathian Basin. In this study, we examined the migration and wintering of the species in an area of southeast Hungary between 2004 and 2019. Data were collected between the beginning of October and the middle of April and during that period we saw Fieldfares a total of 416 times. In addition to the description of migration, the effect of weather on bird numbers was also investigated. According to our results, the species appears in the area in October and disappears in late March and the first half of April. The individuals that migrate in October are likely belonging to the Central European breeding population, while from November the Scandinavian birds can be seen. The maximum number of birds observed during the different years showed significant differences, as did the patterns of movements within the seasons. The relationship between the local weather and the number of birds has been demonstrated over several seasons, which is typical of species with an escape migration.
Leucistic Woodcock (Scolopax rusticola L.) occurrences in Hungary from the second half of the 19th century to the present day
Authors: Bende Attila , Király Angéla , lászló Richárd
Published: December 2019

Publications about curiosities are known in the Hungarian and international ornithological literature since the 1800s. Although studies explaining the processes of pigmentation dysfunctions have been known since the mid-nineteenth century, these specimens still appear only as curiosities in the professional press and the terminology used to specify them is generally incorrect. The analysed genetic abnormalities causing white colour varieties in Woodcock (albinism, leucism, Ino) are due to mutations. By briefly describing the biological background of the defects, this work helps detect colour changes. In this article, we provide a broad overview of partially or completely white Woodcocks (n = 23 expl.) found in international (8 countries) and Hungarian literature. We have supplemented the literature background with our own studies. The large-scale analysis of the variability of colours and patterns was made possible by the countrywide wing sample collection within the biometric module of Woodcock Monitoring, which has been running under the coordination of the Hungarian Hunting Conservation Association since 2010. Within this framework, 12,078 samples were analysed between 2010–2018. We found that pigment deficiency occurred in the sample set only with a proportion of 0.01%. Based on the Hungarian literature and our own samples, we presented the known occurrences on maps of the state territory with boundaries before and after 1921, indicating the causes of patterns of occurrence by migration and frequencies of occurrence.
Chemical and pharmacological characterization of triptans
Authors: Hajnal Kelemen , Bíborka-Erzsébet Filep , Attila Papp Lajos
Published: December 2019

Triptans are specific drugs for migraine attack, their use leads to selective vasoconstriction, while the inflammatory condition that usually occurs during migraine is reduced. The structurally indolamine derivatives are selective agonists of the serotonin 1B/1D receptor. This review presents the history, representatives, production, and physico-chemical properties of triptans, but also discusses their pharmacological properties and mechanism of action.
A first phylogenetic assessment of Dictyonema s.lat. in southeastern North America reveals three new basidiolichens, described in honor of James D. Lawrey
Authors: Forno Manuela Dal , Kaminsky Laurel , Rosentreter Roger , McMullin R. Troy , Aptroot André , Lücking Robert
Published: December 2019

Three species of lichenized basidiomycetes in the Dictyonema clade from southeastern North America are described as new to science: Cyphellostereum georgianum, C. jamesianum and Dictyonema lawreyi, all with a crustose-filamentous growth form. Based on ITS sequences, the species form well-supported monophyletic clades in a phylogeny and are represented by at least two specimens each. They are also distinguishable by morphological and anatomical characters. These new findings emphasize the importance of lichenological studies in North America, especially in historically understudied taxonomic groups, such as basidiolichens. This study is dedicated to James D. Lawrey on the occasion of his 70th birthday.
The Impact of Macro Factors on Apartment Prices in Polish Counties: A Two-Stage Quantile Spatial Regression Approach
Authors: Tomal Mateusz
Published: December 2019

The aim of this study is to identify the economic, demographic, environmental and spatial determinants of residential property prices in Polish counties. Two-stage quantile spatial regression (2SQSR) is the main method of analysis. Additionally, two-stage least squares regression (2SLS) is used.

The estimation results indicate that there are several significant determinants of residential property prices with observable quantile effects. In particular, the findings reveal a very interesting U-shaped pattern among quantile regression coefficients for variables describing unemployment rate, the standard of properties and county area. For the spatially lagged dependent variable, a linear pattern is observable.

Generally, the findings of this study have notable implications for developing housing policies, both at the national and local levels.
Application of AHP Method in Assessment of the Influence of Attributes on Value in the Process of Real Estate Valuation
Authors: Dmytrów Krzysztof , Gnat Sebastian
Published: December 2019

Property valuation in the comparative approach requires the determination of the impact of market characteristics on the formation of prices on the local real estate market. Valuers have a variety of methods for determining weights. Some of them require the collection of a sufficiently large database of information on transactions. However, this is not always possible. In the absence of sufficient data, alternative approaches, including an expert approach, may be used. The goal of the article is the proposal of an expert approach at the stage of assessing the influence of attributes on the value of the real estate. The AHP (Analytical Hierarchy Process) method will be used. On its basis, pairwise comparisons of the importance of attributes will be done by experts (valuers). By means of the AHP method, the weights of each attribute will be obtained and, subsequently, the influence of each attribute on the real estate value will be assessed. Research will be done on the basis of 318 real estates in Szczecin.
Hidden Public Value Identification of Real Estate Management Decisions
Authors: Kazak Jan K. , Simeunović Nataša , Hendricks Andreas
Published: December 2019

Seeing as how cities nowadays have to face many challenges (such as: urban traffic management, revitalization, and adaptation to climate change.), different kinds of urban policies and actions are undertaken. Many of these actions result in changes that influence real estate, mostly by improving the conditions of public services. However, implementation of such urban policies is connected with significant costs that have to be covered by public funds. Therefore, the question arises how we can analyze the assumed benefits from the increase of real estate value? Which tool could allow stakeholders to search for potential added value?

The aim of this paper is to present the methodological approach to improving the communication between stakeholders for the visualization of relations between public actions and potential benefits. The analyses cover benefits that can occur both in public and private budgets. The focal point of this paper is the presentation of causal loop diagrams as a tool that could be incorporated for public value identification on specific investments. The application of the suggested approach is visualized on two examples of urban redevelopment activities. Causal loop diagrams are prepared for the construction of a metro system and implementation of a water retention facility. The results show that both types of urban redevelopment actions have an impact on the creation of value, which can be observed both in public and private benefits. However, not all kinds of activities impact an increase in the market value of real estate and can be measured as incomes in budgets.
Eco-innovation and Economic Growth in the European Union
Authors: Andabaka Ana , Sertić Martina Basarac , Harc Martina
Published: December 2019

Eco-innovation, as a new concept, and green technologies are central to the Europe’s future and at the core of the European Union policies to boost competitiveness, create jobs, and generate sustainable growth for years to come. In this context, eco-innovation is a significant tool that combines decreased environmental impact with a positive socioeconomic impact. This paper highlights the prominent role of eco-innovation and investigates still scarcely explored impact assessment of GDP growth, quality of institutions, and recycling rates on the eco-innovation index in the 28 European Union member states. Specifically, the set of regression analyses that use panel estimation models was undertaken and the system GMM estimator with robust standard errors was used. Econometric analysis indicates that GDP growth rate, quality of institutions, and recycling rate of municipal waste had a statistically significant and positive effect on eco-innovation in the period 2010-2016.
Measuring Return and Volatility Spillovers among Sectoral Stocks in Nigeria
Authors: Fasanya Ismail Olaleke , Oyewole Oluwatomisin , Agbatogun Taofeek
Published: December 2019

This paper examines the return and volatility spillovers of different sectoral stock prices in Nigeria using monthly data from January 2007 to December 2016. We employ the Diebold and Yilmaz (2012) spillover approach and rolling sample analysis to capture the inherent secular and cyclical movements in the sector stocks market.We show that there is substantial difference between the behaviour of the sectoral stock return and volatility spillover indices over time. We find evidence of interdependence among sector stocks given the spillover indices. While the return spillover index reveals increased integration among the sectoral stocks, the volatility spillover index experiences significant bursts during major market crises. Interestingly, return and volatility spillovers exhibit both trends and bursts respectively.
Access to Primary Health Care Services for Youth Experiencing Homelessness: “You shouldn’t need a health card to be healthy.”
Authors: Pitcher Claire , Saewyc Elizabeth , Browne Annette , Rodney Paddy
Published: December 2019

On any given night, thousands of Canadian youth face homelessness in either absolute (living on the street) or relative (couch surfing, staying in emergency shelters) terms.  This study explores influences primary health care access among youth experiencing homelessness in a large Canadian urban centre.  Using a qualitative research design and convenience sampling, 8 youth participated in in-depth individual interviews and 4 clinicians with expertise in working with youth in primary care settings participated in a facilitated solutions-focused dialogue based on findings from the youth interviews.  Data collection occurred from January to November 2016.  Main findings included: (1) Youth experiencing homelessness feel powerless when interacting with health care providers, (2) Health care systems exist as rule-based bureaucracies and (3) Homeless youth are in survival mode when it comes to their health.  The authors offer recommendations to promote more equitable access to primary health care services for homeless youth.
PRIMEIRAS EXPERIÊNCIAS DA VIVÊNCIA NA PRÁTICA PROFISSIONAL: concepções e reflexões de Licenciandos em Ciências Biológicas
Authors: Leite Joici De Carvalho , Inada Paulo , Magalhães Júnior Carlos Alberto De Oliveira
Published: December 2019

O Estágio Supervisionado é o percurso inicial para a inserção de professores em formação no universo escolar.  Entretanto lacunas formativas nos cursos de licenciatura demandam cautela e reformulação. Investigando acerca da formação inicial no curso de Ciências Biológicas, este estudo visou promover um diálogo a respeito das concepções decorrentes das primeiras experiências de 12 licenciandos, enquanto professores estagiários da disciplina de Ciências. Neste viés, os dados foram angariados por meio de respostas a um questionário e analisados seguindo o embasamento teórico da Análise Textual Discursiva. As narrativas retrataram hiatos formativos e curriculares que refletiram o receio da responsabilidade docente, dificuldades em lidar com o desinteresse e indisciplina dos alunos e falhas na transposição didática. Todavia, também apontaram vivências construtivas da prática docente e amadurecimento de concepções. Assim, reestruturações curriculares carecem ser realizadas e, aliadas à disciplina de Estágio Supervisionado, podem promover um ambiente de reflexão e discussão a fim de ampliar conceitos, unir teoria e prática, oportunizando instrumentos fundamentais à ação docente.
Antibacterial therapy of vulgar acne
Authors: Snarskaya E. S.
Published: December 2019

Purpose:to evaluate the efficacy and safety of minocycline in the therapy of medium-heavy and severe forms of acne vulgaris according to modern ideas about pathogenesis of the disease.

Materials and methods. Long-term multi-purpose observation which included 28 patients with the established diagnosis of acne vulgaris, medium-weight and severe forms is made. Patients received monotherapy by Minoleksin® medicine, depending on severity — 50–100 mg a day. Prior to the research and after the end of treatment inspection of the patient with calculation the rash elements, clinical and biochemical blood analysis, a research of function of sebaceous glands, the laser scanning microscopy, a laser Doppler floumetry, definition of the dermatological index of quality of life, photography (was performed at the consent of the patient). In the course of therapy inspection of the patient and assessment of tolerance of drug was performed.

Results.The evidence of efficiency of minocycline in treatment of vulgar acnes of average and heavy severity is obtained that is confirmed by visual dermatological indicators, non-invasive methods of a research (results of a sebumetriya, the confocal laser scanning microscopy, a Doppler floumetriya), indicators of the dermatological index of quality of life. When studying clinical and laboratory indicators security concerns are not revealed. The undesirable phenomena in the course of the research are not registered.

Conclusion.Minolexin® (minocycline) is highly effective and safe drug for treatment of vulgar acnes of average and heavy severity and it can be recommended for practical application in out-patient practice.

Conflict of interest: the author states that there is no potential conflict of interest requiring disclosure in this article.
POLÍTICAS PÚBLICAS E OS DIREITOS REPRODUTIVOS POR REPRODUÇÃO HUMANA ASSISTIDA: PELA EFETIVAÇÃO DOS DIREITOS DA PERSONALIDADE
Authors: Moraes Carlos Alexandre , Amaro Mylene Manfrinato dos Reis
Published: December 2019

A presente pesquisa trata da problemática relacionada a falta de assistência por parte do Estado aos procedimentos de reprodução humana assistida as pessoas inférteis. A Constituição Federal de 1988 instituiu de forma expressa alguns princípios, entre eles o princípio da dignidade da pessoa humana, do planejamento familiar, da parentalidade responsável, bem como, de forma implícita, o direito à procriação, todos com aplicação nas relações familiares e inerentes ao direito de personalidade. É direito de qualquer cidadão o livre planejamento familiar, contudo, existem muitos casais que não possuem condições de arcar com o procedimento de reprodução humana na esfera da rede privada. Na discussão das técnicas permitidas, expõe-se a elaborada pelo Conselho Federal de Medicina, por meio da Resolução n. 2.168/2017, pois, no Brasil não existe uma legislação específica. Com fundamento na dignidade humana e no direito à procriação, o Estado deve proporcionar meios para que todos tenham acesso às técnicas artificiais vez que a lei assegura à igualdade entre todos os cidadãos. Só assim, será respeitado os direitos de personalidade inerentes a todos os seres humanos.
CONSIDERAÇÕES SOBRE RESOLUÇÃO DE CONFLITOS: A (IM)POSSIBILIDADE DE APLICAÇÃO DA MEDIAÇÃO AMBIENTAL EM SUA GESTÃO
Authors: Sell Cleiton Lixieski
Published: December 2019

Esse trabalho possui dois objetivos em relação ao tema da resolução de conflitos. O primeiro é realizar uma abordagem transversal sobre a complexidade dos conflitos ambientais, e em segundo plano situar alguns aspectos positivos e do mesmo modo abordar os desafios da utilização da mediação na gestão. A utilização de métodos como a mediação é percebido pela insuficiência de tutela jurídica sobre os conflitos ambientais.  Para alcançar esses objetivos se utilizou o método hipotético dedutivo. Com a utilização da mediação são caracterizados aspectos vantajosos como diálogo flexível, igualdade de partes, procedimento com menor rigor formal que o rito judicial tradicional, e maior agilidade. Restou evidenciado que a resolução dos conflitos ambientais se difere de outros âmbitos ao passo que são mais complexos e envolvem múltiplas partes. Do mesmo modo, barreiras surgem no contexto da gestão dos conflitos, uma vez que no âmbito ambiental os conflitos aproximam aspectos da Administração Pública que possuem legislação específica e inflexibilidade para acordos. Devido à questão de a aplicação nesse campo ser recente, há insuficiência na regulamentativa que reflete nos setores públicos ou privados em relação à formação de mediadores ambientais.
Nitrite-Phenol-NO Crosstalk: Phenol Oxidation and NO Generation from Nitrite at Copper(II) Sites
Authors: Sakhaei Zeinab , Kundu Subrata , Bertke Jeffery A. , Warren Timothy H.
Published: December 2019

Nitrite is involved in a plethora of biological phenomena that includes tyrosine nitration associated with neurodegenerative disorders and gastric phenol metabolism. Reaction of the b-diketiminato model complex [Cl2NNF6]Cu(k2-O2N) with phenols outlines the coupled generation of NO with phenol oxidation by nitrite at copper(II). Kinetic studies support nucleophilic attack of the hydroxyl group of phenols ArOH on the bound nitrite in [CuII](k2-O2N) to give the copper(II) hydroxide [CuII]-OH along with the O-nitrosated phenol ArONO that ultimately leads to the corresponding biphenol or o-nitrophenol. The especially electron-rich antioxidant a-tocapherol (vitamin E) quickly generates NO upon interaction with [CuII](k2-O2N). X-ray analysis of the oxidation products of the a-tocapherol analogue PMC reveal formation of an elusive O-quinone methide bound to [CuI], revealing two electron oxidation of PMC by [CuII](k2-O2N). These studies illustrate anaerobic pathways that generate NO from nitrite at copper(II) sites that result in phenol oxidation.
Double-Atom Catalysts Provide a Molecular Platform for Oxygen Evolution
Authors: Bai Lichen , Hsu Chia-Shuo , Alexander Duncan , Chen Hao Ming , Hu Xile
Published: December 2019

The oxygen evolution reaction (OER) is an essential anode reaction for the generation of solar and electric fuels through water splitting or CO2 electroreduction. Mixed metal oxides containing Co, Fe, or Ni prove to be the most promising OER electrocatalysts in alkaline medium. However, the active sites and reaction mechanisms of these catalysts are difficult to study due to their heterogeneous nature. Here we describe a general synthesis of Co, Fe, and Ni-containing double-atom catalysts from their single-atom precursors via in-situ electrochemical transformation. Atomic-resolution microscopy and operando X-ray absorption spectroscopy (XAS) reveal molecule-like bimetallic active sites for these supported catalysts. Based on electrokinetic and XAS data, we propose a complete catalytic cycle for each catalyst. These mechanisms follow a similar O-O bond forming step and all exhibit bimetallic cooperation. However, the mechanisms diverge in the site and source of OH- for O-O bond formation as well as the order of proton and electron transfer. Our work demonstrates double-atom catalysts as an attractive platform for fundamental studies of heterogeneous OER electrocatalysts.
Ru-Catalyzed Carbonylative Murai Reaction: Directed C3-Acylation of Biomass-Derived 2-Formyl Heteroaromatics
Authors: Sala Roberto , Roudesly Fares , Veiros Luis F. , Broggini Gianluigi , Oble Julie , Poli Giovanni
Published: December 2019

We describe here the carbonylative Murai reaction applied to 2-formylfurans, 2-formylpyrrols and 2-formylthiophenes. Thanks to the installation of removable imine directing groups, this acylation reaction takes place regioselectively at C3 position of the heterocyclopentadienes. It can be achieved by treating the two reaction partners with a catalytic amount of Ru3(CO)12, in toluene at 120-150 °C, after CO bubbling, at atmospheric pressure. DFT computations of the full catalytic cycle help in deciphering the mechanism of this transformation, and to rationalize the different behaviors depending on the nature of imine directing groups.
Water-Compatible Cycloadditions of Oligonucleotide-Conjugated Strained Allenes for DNA-Encoded Library Synthesis
Authors: Westphal Matthias V. , Hudson Liam , Mason Jeremy W. , Zécri Frédéric J. , Briner Karin , Schreiber Stuart L.
Published: December 2019

DNA-encoded libraries of small molecules are being explored extensively for the identification of binders in early drug-discovery efforts. Combinatorial syntheses of such libraries require water- and DNA-compatible reactions, and the paucity of these reactions currently limit the chemical features of resulting barcoded products. The present work introduces strain-promoted cycloadditions of cyclic allenes under mild conditions to DNA-encoded library synthesis. Owing to distinct cycloaddition modes of these reactive intermediates with activated olefins, 1,3-dipoles and dienes, the process generates diverse molecular architectures from a single precursor. The resulting DNA-barcoded compounds exhibit unprecedented ring and topographic features—related to elements found to be powerful in phenotypic screening.
Single Crystal Growth of High-Pressure Phases of Ice and Salt Hydrate Far Below the Original Melting Point by Mixing Alcohol: Crystal Structure Determination of Magnesium Chloride Heptahydrate
Authors: Yamashita Keishiro , Komatsu Kazuki , Kagi Hiroyuki
Published: December 2019

An crystal-growth technique for single crystal x-ray structure analysis of high-pressure forms of hydrogen-bonded crystals is proposed. We used alcohol mixture (methanol: ethanol = 4:1 in volumetric ratio), which is a widely used pressure transmitting medium, inhibiting the nucleation and growth of unwanted crystals. In this paper, two kinds of single crystals which have not been obtained using a conventional experimental technique were obtained using this technique: ice VI at 1.99 GPa and MgCl2·7H2O at 2.51 GPa at room temperature. Here we first report the crystal structure of MgCl2·7H2O. This technique simultaneously meets the requirement of hydrostaticity for high-pressure experiments and has feasibility for further in-situ measurements.
Ultrafast Formation of the Charge-Transfer State of Prodan Reveals Unique Aspects of the Chromophore Environment
Authors: Baral Swapnil , Phillips Matthew , Yan Han , Avenoso Joseph , Gundlach Lars , Baumeier Björn , Lyman Edward
Published: December 2019

Lipiophilic dyes such as Laurdan and Prodan are widely used in membrane biology due to a strong bathochromic shift in emission that reports structural parameters of the membrane such as area per molecule. Disentangling the factors which control the spectral shift is complicated by the stabilization of a charge-transfer-like excitation of the dye in polar environments. Predicting the emission therefore requires modeling both the relaxation of the environment and the corresponding evolution of the excited state. Here an approach is presented in which (i) the local environment is sampled by classical molecular dynamics (MD) simulation of the dye and solvent; (ii) the electronically excited state of Prodan upon light absorption is predicted by numerical quantum mechanics (QM); (iii) iterative relaxation of the environment around the excited dye by MD coupled with evolution of the excited state is performed; (iv) the emission properties are predicted by QM. The QM steps are computed using many-body Green's functions theory in the GW approximation and the Bethe-Salpeter Equation with the environment modeled as �fixed point charges, sampled in the MD simulation steps. Comparison to ultrafast time resolved transient absorption measurements demonstrates that the iterative MM/QM approach agrees quantitatively with both the polarity dependent shift in emission and the timescale over which the charge transfer state is stabilized. Together the simulations and experimental measurements suggest that evolution into the charge-transfer state is slower in amphiphilic solvents.
PROVISIONS CONCERNING THE ORGANIZATION OF EVENTS FOR THE PROMOTION OF PRODUCTS ON PHARMACEUTICAL MARKET IN ROMANIA
Authors: IOSIF Alina Natalia , GURGU Elena
Published: December 2019

For the purpose of writing this paper, we  were motivated to choose this subject as it is a core part of the pharmaceutical companies' business strategy of promoting medicines. Regarding the importance of the research theme and the business environment, it is crucial that anyone connected to this business should realize the importance of organization, details, good deployment and impact of each event. In this respect, marketing can be seen as a true system of economic activities related to the programming of products and services that have the role of satisfying the requirements of current and potential consumers considerably, but is also linked to prices, promotion and distribution products or services.               Having knowledges about how important is the marketing part of pharmaceutical market, taking in consideration the huge budgets that medical and pharmaceutical companies spend on the events organized in this domain, we consider that a company which is able to have a new approach and a new vision for the organization of events and sharing medical education to doctors and medical information to patients will have a big success.
The strategy of promoting and selling medicines on the Romanian market
Authors: GURGU Elena , STANESCU Ioan Aurelian
Published: December 2019

For the purpose of writing this paper, I was motivated to choose this subject as it is a core part of the pharmaceutical companies' business strategy of promoting medicines. Regarding the importance of the research theme and the business environment, it is crucial that anyone connected to this business should realize the importance of organization, details, good deployment and impact of each event. In this respect, marketing can be seen as a true system of economic activities related to the programming of products and services that have the role of satisfying the requirements of current and potential consumers considerably, but is also linked to prices, promotion and distribution products or services.               Having knowledges about how important is the marketing part of pharmaceutical market, taking in consideration the huge budgets that medical and pharmaceutical companies spend on the events organized in this domain, I consider that a company which is able to have a new approach and a new vision for the organization of events and sharing medical education to doctors and medical information to patients will have a big success.
PENGARUH WAKTU PENAMPUNGAN SEMEN TERHADAP GERAKAN MASSA SPERMATOZOA DAN TINGKAH LAKU KOPULASI PEJANTAN DOMBA GARUT
Authors: Herdis Herdis
Published: December 2019

The study was carried out to observe the influence of semen collectiontime toward the copulation behavior and the movement of massspermatozoa of garut rams. The semen of seven Garut rams wascollected twice a week. It indicates that the difference of semen collectiontime causes the difference of air temperature. The semen collected at6:00 am showed better mass sperm movement than at 12:00. Thesemen collected at 06:00 am; 9:00 am and 12.00 am did not show anyeffect toward the preejaculation copulation behavior. Otherwise thesemen collected at 06:00 am delivered longer intromisi period than at12:00 am.
Pengaruh Intensitas Naungan Dalam Aklimatisasi Pertumbuhan Planlet Gaharu (Aquilaria beccariana)
Authors: Mulyono Daru
Published: December 2019

The objective of this research is to know the optimal shading intensity in the acclimatization of Gaharu planlet growth (Aquilaria beccariana). The research was carried out in Agroindustry and Biotechnology Laboratory, Ciampea, Bogor, West Java from February to April 2007. The research used Complete Randomized Design in order to know the effect of shading net treatment: P1 (shading intensity 25 %), P2 (shading intensity 55 %), and P3 (shading intensity 75 %). The results of the research showed that after eight weeks of planting with the treatment of shading intensity 55 % was significantly better than shading intensity 25 % and shading intensity 75 % to the growth of Gaharu planlet in terms of plant heigh, sum of leaf, sum of root, and length of root.Penelitian ini bertujuan untuk mengetahui intensitas naungan yang optimal dalam aklimatisasi pertumbuhan planlet Gaharu (Aquilaria beccariana). Penelitian ini dilaksanakan di Laboratorium Agroindustri dan Bioteknologi, Ciampea, Bogor, Jawa Barat mulai Februari sampai April 2007. Penelitian ini menggunakan Rancangan Acak Lengkap untuk mengetahui pengaruh perlakuan naungan: P1 (intensitas naungan 25 %), P2 (intensitas naungan 55 %), dan P3 (intensitas naungan 75 %). Hasil penelitian menunjukkan bahwa setelah delapan minggu penanaman dengan perlakukan intensitas naungan 55 % memberikan hasil yang lebih baik dibandingkan dengan intensitas naungan 25 % dan intensitas naungan 75 % terhadap pertumbuhan planlet Gaharu dalam tinggi tanaman, jumlah daun, jumlah akar, dan panjang akar.Keywords: Gaharu, shading, acclimatization
Eksistensi Hukum Keluarga Islam di Indonesia dalam Kontestasi Politik Hukum dan Liberalisme Pemikiran Islam
Authors: Islamy Athoillah
Published: December 2019

This research aims to understand the existence of the Compilation of Islamic Law (KHI) and its status in the political perspective of the formation of law. In addition, it is also to understand the existence of KHI in the midst of the liberalism movement of Islamic legal thinking in Indonesia. This research is a qualitative research in the form of literature review. While the type of legal research in this study, namely historical normative legal research. There are two big conclusions from the results of this study. The First, the formation of KHI accommodates orthodox and responsive legal strategies. The second, the existence of KHI remains consistent even though there have been many thoughtful efforts and studies that have criticized it. This is due to the criticism only as the impact of the opening of the democratic climate for the liberal movement of Islamic thought in the public sphere.