bluuebunny/crossref_metadata_2025 huggingface dataset:
Therapeutic Drug Monitoring (TDM) Teofilin sebagai Antiasma di Indonesia
Authors: Elizabeth Maria , Rusdiana Taofik
Published: July 2023

Therapeutic Drug Monitoring (TDM) ini adalah salah satu pelayanan farmasi klinik yang ditujukan untuk meningkatkan efektivitas terapi dan meningkatkan keselamatan pasien. TDM ini banyak digunakan dalam penggunaan obat dengan indeks terapi sempit atau dapat menimbulkan efek toksik dalam perubahan kecil dosis, seperti teofilin. Teofilin adalah obat golongan xantin yang masih sering digunakan di Indonesia dan memiliki efek bronkodilatasi sehingga dapat digunakan dalam pengobatan asma atau penyakit paru obstruksi kronis (PPOK). Obat ini memiliki indeks terapi sempit dengan dosis terapeutiknya antara 10-20 mg/L, konsentrasi di atas 20 mg/L dapat menimbulkan efek samping berbahaya seperti mual, muntah, asidosis metabolik, perdarahan saluran cerna, bahkan kematian. Teofilin merupakan salah satu obat yang perlu dilakukan monitoring terkait perbaikan gejala dan kadar obat dalam plasma. Oleh karena itu, tujuan dari penulisan artikel ini adalah untuk melihat monitoring teofilin yang telah dilakukan di Indonesia dengan pendekatan studi literatur menggunakan kriteria inklusi dan eksklusi. Hasil yang didapatkan yaitu masih sedikit rumah sakit yang melakukan therapy drug monitoring terkait kadar teofilin dalam darah.
ANALISIS BAHAN KIMIA OBAT ASAM MEFENAMAT DALAM JAMU PEREDA NYERI YANG BEREDAR DI NGAWI DAN ONLINE SHOP SECARA KLT DAN SPEKTROFOTOMETRI UV-VIS
Authors: Harjanti Reslely , Pratiwi Intan , Sarimanah Jamilah
Published: July 2023

Salah satu bahan kimia obat yang sering disalahgunakan pada sediaan jamu pereda nyeri yaitu asam mefenamat. Asam mefenamat merupakan golongan obat antiinflmasi non steroid (OAINS). Penambahan asam mefenamat dalam jamu bertujuan meningkatkan efek anti nyeri, namun penggunaannya dapat menimbulkan efek berbahaya bagi tubuh di antaranya gangguan saluran cerna, anemia hemolitik, dan kejang. Tujuan penelitian ini adalah untuk mengetahui kandungan asam mefenamat dalam sediaan jamu pereda nyeri yang beredar di Ngawi dan online shop. Sampel yang digunakan pada penelitian ini yaitu beberapa merek jamu pereda nyeri dari 4 toko jamu (A,B,C,dan D). Pengambilan sampel dilakukan dengan metode purposive sampling berdasarkan kriteria inklusi yang ditetapkan. Sampel dianalisis kualitatif dengan metode kromatografi lapis tipis (KLT) dengan fase gerak sikloheksana : kloroform : metanol : asam asetat glasial (60:30:5:5) dan fase diam silika GF 254. Analisis kuantitatif dengan metode spektrofotometri UV-Vis. Hasil penelitian diperoleh 10 dari 16 sampel jamu pereda nyeri positif asam mefenamat dengan kadar berkisar 1,28%-7,30%. Metode analisis spektrofotometri UV-Vis sesuai untuk analisis asam mefenamat dalam jamu pereda nyeri berdasarkan hasil validasi memenuhi persyaratan meliputi linearitas dengan nilai r=0,99956, akurasi 8 ppm sebesar 100,32%, 10 ppm sebesar 100,84%, 12 ppm sebesar 100,61%,  presisi sebesar 1,33%,  LOD 0,8914299023 ppm, dan LOQ 2,701302734 ppm.
Pengaruh Pelarut N-Heksan, Etil Asetat, Dan Etanol 96% Terhadap Kadar Flavonoid dan Aktivitas Antioksidan Kulit Buah Lamtoro (Leucaena leucocephala)
Authors: Ina bulu Atalia tamo , Novembrina Metrikana
Published: July 2023

Limbah kulit buah lamtoro di Indonesia dihasilkan dalam jumlah banyak sehingga dapat menjadi masalah bagi lingkungan jika tidak di Kelola dengan baik. Ekstrak kulit buah lamtoro mengandung senyawa kimia seperti flavonoid, alkaloid, saponin, fenolik dan tannin. Senyawa Flavonoid sebagai salah satu golongan fenolik yang banyak terdapat pada jaringan tanaman dapat berperan sebagai antioksidan. Penelitian ini bertujuan untuk menguji pengaruh pelarut N-heksan, etil asetat, dan etanol 96% terhadap kadar flavonoid dan aktivitas antioksidan kulit buah lamtoro (Leucaena leucocephala).

 

Kulit buah lamtoro di buat simplisia dan diekstraksi dengan metode maserasi menggunakan pelarut N-heksan, etil asetat, dan etanol 96% secara terpisah selama 3x24 jam. Setiap ekstrak dianalisis untuk menentukan kadar flavonoid dengan metode spektrofotometri UV-Vis dan aktivitas antioksidan menggunakan metode DPPH (1,1-difenil-2-pikrilhidrazil).

 

Hasil analisis menunjukkan bahwa pelarut etanol 96% memberikan ekstrak dengan kadar flavonoid tertinggi, diikuti oleh etil asetat dan N-heksan berturut-turut sebesar 15,345 µg/g, 14,899 µg/g, dan 10,234 µg/g. Selain itu, aktivitas antioksidan ekstrak kulit buah lamtoro juga terbukti lebih tinggi pada ekstrak etanol 96% dibandingkan dengan ekstrak etil asetat dan ekstrak n-heksan dihitung dengan nilai IC50 berturut-turut adalah 39,914 ppm, 30,788 ppm, dan 164,304 ppm. Berdasarkan penelitian ini, dapat disimpulkan bahwa penggunaan pelarut etanol 96% menghasilkan ekstrak kulit buah lamtoro dengan kadar flavonoid yang lebih tinggi dan aktivitas antioksidan yang lebih kuat dibandingkan dengan penggunaan N-heksan atau etil asetat sebagai pelarut. Hasil ini menunjukkan bahwa kulit buah lamtoro memiliki potensi sebagai sumber flavonoid dan antioksidan yang bermanfaat.
PROFILE OF THE USE OF TRADITIONAL MEDICINE IN PEGANDON KENDAL VILLAGE COMMUNITIES
Authors: Suwarni Sri , Septiyana Ria , Fajaryanti Nita , Indrasari Ferika
Published: July 2023

Penelitian ini membahas tentang profil penggunaan obat tradisional di Desa Pegandon, dimana penelitian ini bertujuan untuk memperoleh gambaran produsen jamu tradisional yang ada di wilayah desa Pegandon dan gambaran penggunaan obat tradisional pada usaha jamu tradisional di wilayah desa Pegandon. Penelitian ini di lakukan menggunakan metode deskriptif dengan kuisioner sebagai pengumpul data. Responden dalam penelitian ini adalah masyarakat desa Pegandon. Hasil Penelitian menunjukkan bahwa penggunaan obat tradisional terbanyak di desa Pegandon merupakan wanita (100%), usia 31-40th (40%), pekerjaan IRT (92%), pendidikan terakhir SLTA (47,7%). Jenis Penyakit nya kebanyakan diare (30%) dan nyeri haid (30%) dengan jangka waktu menderita sakit paling banyak dialami kurang dari satu minggu (96%), tindakan  yang di lakukan ketika sakit oleh responden paling banyak periksa dokter, puskesmas atau rumah sakit (68%), kebanyakan tujuan menggunakan obat tradisional untuk menyembuhkan penyakit yang mendadak/ringan (34%) dengan membeli obat tradisional di penjual jamu tradisional (42%), bentuk sediaan yang paling banyak di pakai responden dalam bentuk jamu (46%) dengan rata-rata lama penggunaan 1 hari saja (46%), sumber informasi paling banyak di dapatkan dari keluarga (30%) dengan alasan terbuat dari bahan alami (90%), banyaknya pemakaian kebanyakan satu sendok makan (40%), obat tradisiona yang di gunakan paling banyak tidak memunculkan efek samping (92%), ketika muncul efek samping beberapa responden tetap melanjutkan obat tradisonal (2%), tetapi ada yang pergi ke dokter atau beralih ke obat modern (40%), dan ada yang menghentikan pemakaian obat tradisional (58%).

 

Kata kunci: Gambaran Penggunaan, Obat tradisional, Desa pegandon,
Contrast-agnostic deep learning–based registration pipeline: Validation in spinal cord multimodal MRI data
Authors:   NeuroPoly Lab, Institute of Biomedical Engineering, Polytechnique Montreal, Beal E. , Cohen-Adad J.
Published: July 2023

Medical image registration can be challenging, in that optimal solutions depend on the application domain (unimodal, multimodal, intra-subject and inter-subject), anatomical sites (e.g., brain, spinal cord (SC) and lungs), dimensionality of the data (2D, 3D and 4D), deformation constraints (rigid, affine and nonlinear) and computational time. Solutions that could accommodate a large variety of applications while producing satisfactory results are needed. SynthMorph was recently introduced as an unsupervised deep learning–based registration method. A particularly interesting feature is that training is performed on synthetic data so that registration becomes agnostic to image contrast and anatomy. However, SynthMorph is particularly sensitive to the initial closeness of the images. In this work, we extend the SynthMorph method by developing a cascaded pipeline of two models that can accommodate large and fine deformations, respectively. We also validate this pipeline for the registration of intra-subject multimodal and inter-subject uni/multimodal MRI data of the SC. This task is known to be particularly difficult due to the vicinity of multiple tissue types whose morphometrics can vary substantially across subjects and contrasts. Evaluation of the method was conducted on a publicly available dataset (spine-generic, 267 subjects) and was compared with a state-of-the-art benchmark: Spinal Cord Toolbox and Advanced Normalization Tools. Results demonstrate better registration accuracy compared with the benchmark and about 24–30 times faster on CPUs depending on the image size. This proposed pipeline provides an easy-to-use, accurate and fast solution for multimodal 3D registration. The code and trained models are freely available at https://github.com/ivadomed/multimodal-registration.
Prática pedagógica contextualizada na educação do âmbito da Escola do Campo José Bonifácio Barbosa de Andrade.
Authors:   , Francisco da Silva Irenildo
Published: July 2023

O solo é um dos recursos naturais mais importante oferecido pela natureza, responsável pela sobrevivência e manutenção da vida no planeta Terra. Por esse motivo se torna bastante importante os cuidados com a preservação e seu uso responsável de forma sustentável desse recurso tão precioso por parte dos seres humanos. Nessa perspectiva desenvolvemos a pesquisa intitulada “Prática pedagógica contextualizada na educação do solo no âmbito da Escola do campo José Bonifácio Barbosa de Andrade” que teve por objetivo geral apresentar a mediação realizada na sala de aula mostrando a importância da educação em solos no âmbito da educação contextualizada na Escola José Bonifácio Barbosa de Andrade, indicando as diversas possibilidades de trabalhar a temática de forma contextualizada através de atividades já realizadas no âmbito escolar. A mesma foi realizada através do pressuposto da pesquisa qualitativa no âmbito da pesquisa-ação e aplicação de questionários aos professores que atuam na referida escola. Verificamos que a pesquisa foi bastante satisfatória, a mesma, despertou nos alunos um grande interesse em participar e aprender um pouco mais sobre o solo, a importância de usar de maneira consciente e sustentável. Como também, identificamos que os professores trabalham o tema solo em suas práticas em sala de aula de forma contextualizada, mesmo trabalhando com disciplinas diversas, mostrando que a temática é de fato tratada de forma diferenciada com a devida importância no contexto do Semiárido Brasileiro.
“De noite a cerca anda”: a grilagem de terras no município de Sumé-PB e sua relação com o ensino de Ciências Humanas e Sociais de uma escola do campo.
Authors:   , Barbosa Carneiro Iris
Published: July 2023

O objetivo deste trabalho foi o de analisarmos de que maneira o tema grilagem de terras no município de Sumé-PB é abordado (ou não) no ensino de Ciências Humanas e Sociais de uma escola do campo. Foram nossos interesses específicos: problematizarmos, do ponto de vista histórico, como se conformou a questão agrária no Brasil, na Paraíba e no município de Sumé - PB; estudarmos os conflitos por terra ocorridos no Brasil, na Paraíba e no município de Sumé- PB, especificamente os que envolveram a grilagem de terras; e analisarmos de que maneira a grilagem de terras ocorrida no município de Sumé-PB é tomada no ensino de Ciências Humanas e Sociais de uma escola do campo. Como aporte teórico-metodológico para compreensão das problemáticas levantadas sobre a questão agrária faremos uso do Materialismo Histórico Dialético, onde iremos investigar as relações diretas entre as lutas de classes que de modo específico se expressam nos conflitos dos grandes proprietários/latifundiários com os camponeses que possuem, em sua grande maioria, pequenas propriedades/posses rurais. A coleta de dados se deu através de consulta a uma bibliografia geral e específica e a um conjunto de fontes diretas, tais como: sesmarias, dados do IBGE, do Sistema Nacional de Cadastro Rural (SNCR) e do Cadastro Ambiental Rural (CAR), Leis brasileiras, literatura de cordel, entrevistas e questionários semiestruturados e Planos de Cursos. Os estudos realizados permitiram compreendermos a realidade agrária no município de Sumé- PB, um tema que, até o presente momento, foi muito pouco estudado e analisado academicamente. Buscar entender a realidade deste município em que residimos, portanto, enquanto docente em formação, significa, também, se propor a intervir em suas contradições em favor das classes marginalizadas. As conclusões permitiram, por fim, entendermos que esta realidade agrária brasileira e local, particularmente, a grilagem de terras não é abordada como conteúdo didático no ensino das Ciências Humanas e Sociais da escola do campo UMEIF “José Bonifácio Barbosa de Andrade” do município de Sumé-PB que se propõe como referência de Educação do Campo.
A produção de recursos didáticos com grãos de sementes da paixão: uma abordagem contextualizada na compreensão do processo de regionalização do território brasileiro.
Authors:   , da Silva Carvalho Genilda
Published: July 2023

O ensino de Geografia nas escolas do campo de forma contextualizada é de suma importância para que os alunos compreendam os elementos que compõem o espaço geográfico. Ou seja, o mundo e suas problemáticas sociais e ambientais. Contudo, para que o ensino desse componente curricular seja proveitoso, devem-se considerar as necessidades dos alunos e os seus dia a dia, pois é fazendo a relação com o meio em que convivem que é possível se ter um ensino de qualidade na Geografia. Dessa forma, esta pesquisa, tem por objetivo relatar o processo de construção de recursos didáticos utilizando grãos das sementes da paixão, tendo por base a temática “O PROCESSO DE REGIONALIZAÇÃO DO TERRITÓRIO BRASILEIRO” no âmbito da pesquisa-ação, identificando sua contribuição no processo de ensino-aprendizagem de forma contextualizada no contexto escolar. Para execução dessa pesquisa, utilizamos os pressupostos da pesquisa qualitativa, através da Pesquisa-Ação, que foi dividida em momentos de capacitações/produções e experimentação nos contextos acadêmico e escolar. Verificamos que a produção e experimentação desse recurso didático foi de grande importância na compreensão da temática por parte dos alunos, a interação foi bastante positiva em relação aos conteúdos abordados, desde atenção com a intervenção, trazendo as sementes, até a confecção das figuras representando os mapas. Feito a avaliação, podemos observar que os alunos aprenderam a identificar cada critério de regionalização do Brasil e suas respectivas características, desta forma identificamos o quanto foi válido a oportunidade de produzir com os próprios alunos esse recurso didático na aprendizagem dos mesmos, contribuindo para um ensino de qualidade na disciplina de Geografia para as escolas do campo de forma contextualizada.
A aula de campo na educação infantil como estratégia didática para a contextualização da educação.
Authors:   , Clara da Silva Lima Maria
Published: July 2023

Este trabalho se insere na linha de pesquisa Processos de Ensino e Aprendizagem e Didática de Conteúdos Específicos na Educação Contextualizada, do Curso de Especialização em Educação Contextualizada para a Convivência com o Semiárido, do Centro de Desenvolvimento Sustentável do Semiárido, da Universidade Federal de Campina Grande. Seu objeto de estudo consistiu na percepção das professoras da Educação Infantil sobre a Aula de Campo como estratégia didática para contextualização do Ensino. Nesta perspectiva nos colocamos como objetivo geral: analisar como as professoras da Educação Infantil compreendem a aula de campo como estratégia didática para contextualização do conhecimento. Especificamente nossos objetivos foram: Identificar na proposta curricular do município se, e como, incorpora a contextualização da Educação como princípio e metodologia; identificar na percepção das professoras da Educação como a proposta curricular por campo de experiência possibilita a contextualização. Com base nestes objetivos nossas questões de pesquisa foram: a proposta Curricular da Educação Infantil do Município de São João do Tigre, incorpora a contextualização como princípio e fundamento? A proposta curricular por Campo de Experiência tem possibilitado está contextualização? As professoras compreendem a aula de campo como estratégia didática para contextualização? Assim, adotamos como conceitos centrais da pesquisa: Educação Infantil (KULMAN, 2003; LDB, 1996); Currículo por Campo de experiência (SACRISTAN, 1999; SILVA, 1996); Contextualização da Educação (REIS, 2010; MARTINS, 2006); Aula de Campo (ANASTASIOU E ALVES, 2004); Estratégia Didática (BARDIM, 2011). A abordagem qualitativa (MINAYO, 2010) orientou o estudo do tipo documental com a análise dos documentos da política da Educação Infantil e descritivo ao realizar a escuta da fala das professoras para identificar sua visão sobre a aula de campo, a contextualização da educação e o currículo por campo de experiências. A pesquisa teve como campo empírico o município de São João do Tigre no Cariri Paraibano e como sujeitos colaboradores as professoras da Educação Infantil da Rede Pública Municipal. Como resultados identificamos que: a proposta curricular do município possibilita a partir do estudo dos campos de experiência o uso de temáticas que favoreçam a contextualização na educação infantil usando como ferramenta a aula de campo. Contudo, essa prática não está incluída nos planejamentos rotineiros, estas só acontecem no desenvolvimento de projetos didáticos, ou seja, com eventualidade. Por fim, a pesquisa possibilitou descobertas e aprendizados e novas perspectivas para as professoras em relação ao trabalho interdisciplinar, evidenciando a relevante importância que tem a inserção de aulas não convencionais para o cotidiano escolar.
Tecnologias analíticas e de produção vegetal da aroeira (Myracrodruon urundeuva Allemão).
Authors:   , Paulo Pereira de Lima João
Published: July 2023

Myracrodruon urundeuva Allemão (Anacardiaceae) é uma espécie de ocorrência na região nordeste do Brasil, conhecida popularmente como aroeira-do-sertão, uma das plantas cujo uso medicinal é dos mais difundidos na região, especialmente por suas propriedades etnofarmalógicas, incluindo atividades antimicrobianas. De acordo com o conhecimento documentado sobre o uso fitoterápico da aroeira, a mesma foi incluída na lista oficial de Plantas ANVISA, mas devido ao extrativismo inadequado a espécie foi considerada na Lista Oficial das Espécies da Flora Brasileira Ameaçadas de Extinção elaborada pela Fundação Biodiversitas sob os auspícios do Ministério do Meio Ambiente. Este trabalho buscou desenvolver um modelo metodológico para avaliar a integridade da M. urundeuva considerando a caracterização biológica e térmica das sementes. As sementes foram estudadas em três diferentes estágios de maturação I verde, II intermediário e III maduro, utilizando diferentes métodos analíticos para sua caracterização. O material foi coletado nos municípios de Sumé e São João do Cariri na região semiárida da Paraíba, Brasil. Na caracterização biométrica determinou-se o diâmetro, a largura e a espessura de 100 sementes em cada estágio de maturação. Sementes em diferentes fases tiveram comprimento médio, respectivamente, da fase I (4,44 mm), fase II (4,42 mm) e fase III (3,33 mm). Na caracterização Termogravimétrica foi determinado teor de umidade pelo método de estufa com circulação a ar na qual a amostra S1, S2 e S3 apresentou 74%,56% e 8,8% respectivamente, para as amostras de SJ1, SJ2 e SJ3 apresentaram 69%, 9,3% e 3,4% da umidade presente nas sementes, e o teor de cinzas foi determinado pela metodologia 018/IV Resíduo por incineração – Cinzas (IAL, 2005). As amostras foram analisadas por técnicas termogravimetricas (TG) nas razões de aquecimento 5, 10, 20 e 40 °C.min-1 e análise térmica diferencial (DTA) 10°C.min-1. Nas curvas TG observaram-se seis eventos de degradação de massa, tanto na atmosfera inerte como oxidativa, indicando similaridade entre os perfis tendo como resultados da energia de ativação S1, S2 e S3 102,37, 94,41, 94,34 jmol-1 e SJ1, SJ2 e SJ3 97,66, 100,85 e 96,75 jmol-1. As curvas DTA mostraram dois eventos exotérmicos nas faixas de temperatura de 250°C a 380°C e 420°C a 510°C, e o pico variando entre 312 – 349 °C e 449 – 475°C. A pirólise acoplada a cromatografia gasosa / espectrometria de massa (PYR-GC / MS) apresentou fragmentos semelhantes ao diferentes estágios. Para a produção vegetal e acompanhamento do desenvolvimento dos brotos utilizou-se seis árvores matrizes e 20 baldes por matriz, sendo depositadas 4 sementes por balde e 80 sementes por matriz. Os resultados da produção vegetal de M. urundeuva foram apresentados por sua emergência, desenvolvimento e mortalidade.
The Intervention of Physiotherapy in the improvement of facial mimicry in a Peripheral Facial Palsy associated with a Preg-nancy: A Case Report
Authors: Felício João Carlos Martins
Published: July 2023

Peripheral Facial Palsy is a peripheral paralysis of the facial nerve that results in muscle weakness on one side of the face. Patients develop unilateral facial paralysis within one to three days with involvement of the facial musculature associated or not with neurological alterations, the best-known being Bell's Palsy. Symptoms usually peak in the first week and then gradually subside over three weeks to three months. In this context, a female patient with the clinical Diagnosis of Peripheral Facial Paralysis, was subjected to an intervention plan in Physiotherapy lasting 4 months (sessions of 45 minutes at a frequency of 3 times a week), with the particularity of be 28 weeks pregnant at the start of the sessions. After the end of the sessions, there was a considerable improvement in facial movements, translating into considerable functional changes. The patient acquired greater motor recruitment in flaccid muscles, greater facial symmetry, and consequently greater autonomy in eating, chewing, containing liquids and intraoral sensibility.
The Pseudonym which Turned into the Art
Authors:   Namangan State University, Qurbonov Abdulhamid
Published: July 2023

This article is devoted to the problem of the relation between Navoi and his pseudonym “Navo”. For the great poet, pseudonym (taxallus) was not only a poetic name, but also was a special opportunity for the manifestation of his talent. As Babur said, Navoi was a poet who wrote “more and better than others.” “Hamsa”, especially “Hazoyin ul Maoniy”, includes hundreds of perfect couplets. Due to these couplets are a new type of the art that can be called navo (melody) and Navoi art. On the basis of this lies Navoi’s original point of view about high poetic symmetry. Navoi confirmed that every poetic work or a separate couplet must be created according to the rules of high symmetry; all poetic elements of the work must be related between poetic content both forms and meaning. The article considers the literary and Sufic meanings of Navoi, navo (melody), benavo, Navoe, through an analysis of a number of couplets from poet’s work.
The Creative Works of Ahmad Tabibiy and his Divan’s Copies which was named “Munisu-l-ushshoq”
Authors:   Alisher Navo'i Tashkent State University of Uzbek Language and Literature, Amonov Shermuhammad
Published: July 2023

Ahmad Tabibiy is one of the most active representatives of Uzbek literature in the late XIX and early XX centuries. He is known as a natu-ral translator, dosonavis, tazkiranavis. He continued the classical literary tradition with dignity and composed five poetic Devonian works. At the moment, the sources of the poet’s works are stored in various libraries and funds of the republic.The poet’s contribution to the literary activities of his time, to the popularization of the literature of peoples and the literary works of fraternal peoples is especially important. Ahmad Tabibiy continued the traditions of classical artists and worked in almost all genres. Even in his works there are some of his own genres that other poets do not have. It is obvious that there has not been investigation in the literature history on Turkic devons of Ahmad Tabibiy who is bilingual poet of literal epoch of Khiva.This article deals with Ahmadjon Tabiby’s creativity his lyric works proceedings “Munis ul-ushshoq” and scientific descriptions litographic manuscripts of devon. It gives information about distnictions between lito-graphic and mannual manuscripts. Moreover, the paper presents founda-tions of creativity heritage of Tabiby, genres of lyrics of poet.
In the late nineteenth and early twentieth Centuries, the Progress of Lexicography and the Position of the Dictionary Titled “Lughati salos” in the Lexicography
Authors:   Institute of Oriental Studies named after Abu Rayhan Beruni of the Republic of Uzbekistan, Mahkamova Odina
Published: July 2023

Lexicography is one of the most important sections of linguistics the theme of this article aims to learn the book of “Lug‘ati salosi” which is an essential instruction for Arabian and Persian learners Exploring this book properly enables us to stady lexicography Turkic languages as wellas making out classic works and the history of lexicography. This article is devoted to obtain: general information about “Lug‘ati salos”, information about 19th century linguistics, brief information about Salokhiddin Toshkandi, to describe the literary aspects of the work, presentation of the introductory part of the work, information about the margin of the work, being familiar to its construction, analizing every section of the book.
The Comparison of the two Copies of Mahmud Zamakhshariy’s Work “Al qistos fi ilm al-aruz” Brought from Berlin and Istanbul
Authors:   Tashkent State University of Oriental Studies., Xujanova Dildora
Published: July 2023

This article deals with the scientific significance of the manuscript work on the theory of Arabic Aruz “Al-Kistas al-mustakim fi ilm al-aruz”, written by the great scholar from Mawarounnahr, Mahmoud Zamakhshari, who made a significant contribution to world culture. The article also examines the copies of this source stored in the collections of the state libraries of Istanbul, Ankara, Cairo, Berlin and other cities. In the article for the first time in textual and literary sources it was made a comparative analysis of the copy of the work “al-Kistas” stored in the “Tubinger” Foundation, Berlin, with other manuscript copies, in particular with the copy stored in the Fund “Rais al-Kuttab “ in the Suleymania library of Istanbul. As a result, it turns out that the copy of “Rais al-kuttab” is complete, well preserved, has no gaps and shortcomings, so it is suitable for compiling a critical text of the work “al-Kistas”. The copy of “Tubinger” differs from other copies by the structure and originality in the presentation of the material on on meters (buhur), as well as in the originality of the poems given in the Aruz circles. It should also be noted that the third part of this manuscript includes excerpts from the work on Aruz “Ar-Risala al-Andalusiya”, belonging to the scientist Abu al-Jaish al-Andalusi. The work with great skill uses the poetic examples given to illustrate meters, which were written by Abu al-Jaish al-Andalusi himself, and not found anywhere else. It was revealed in the process of research and comparative analysis that the examples for the illustrations of Aruz circles were written by Mahmoud Zamakhshari himself.
The Inscriptions on the Gravestones of Kultegin and Bilga khan: Reading and Interpretation of the Texts
Authors:   Alisher Navo'i Tashkent State University of Uzbek Language and Literature, Sodiqov Qosimjon
Published: July 2023

The inscriptions Kul Tigin and Bilga-kagan are one of the most ancient monuments of ancient Turkic historiography, as well as written literature and the literary language. The historian and writer Yollug Tigin used his knowledge and skills to write this monument. The structure of the epigraphic text is ideal and very complex.Most of these texts were spoken from the mouth of Bilga Kagan. The writer Yollug Tigin wrote the text of the stele that his father uttered. Three years later, after the death of Bilga Kagan, Yollug Tigin himself wrote this inscription. Kagan took the speech written for the previous monument and included it here. However, the next part is not a literal repetition of the previous text, but a revised, edited, finished version of the author. This is the first, but also a wonderful example of the art of text editing.From the texts of Kul Tigin and Bilga Kagan, you can find out what appeal to the people. This official appeal marks the beginning of the call, namely the name Täŋri-täg Täŋri yaratmïš türk Bilgä qaγan sabïm. Kagan began all international and diplomatic letters, appeals to the people with this title.The title of Bilga Kagan is the first, but also a classic example of medieval Turkic titles. All its components are completely compact and elegant. This indicates a high level of documentation of the ancient Turkic language.The title of Bilga Kagan was not only a model of the era of his time, but also served as a model and standard for all official medieval documentary labels. The traditions of the Kok-Turkic documentary tradition continued throughout the following centuries. The owners of the Turkic Kaganate and states began their labels with such titles.
Generative AI for Business Decision-Making: A Case of ChatGPT
Authors: Chuma Euclides Lourenco , De Oliveira Gabriel Gomes
Published: July 2023

ChatGPT (Generative Pretrained Transformer) is a chatbot using artificial intelligence (AI) launched by OpenAI, which is an AI research and deployment company. The ChatGPT has taken the technology world by storm. The ChatGPT is a trained AI model that can chat almost like a human. The dialog format allows the ChatGPT to answer follow-up questions, admit mistakes, challenge incorrect premises, and reject inappropriate requests. The ChatGPT can be utilized for compiling research, drafting marketing content, brainstorming ideas, delivering aftercare services, increasing customer engagement, and many others. The ChatGPT can provide enormous opportunities for companies leveraging this breakthrough technology strategically. Thus, we evaluate ChatGPT as a tool in common business decision-making cases in the current study. For example, the ChatGPT was asked about the impacts of a hypothetical merging of two supermarket chains in Sweden. In another example, the ChatGPT was asked about recommendations for investment in a Brazilian oil company. Finally, it was asked about the factors that influence online shopping behavior. The results are significant and demonstrate the tremendous potential of the ChatGPT in revolutionizing the corporate world.
Crystallisation and characterisation of muscle proteins: a mini-review
Authors: Govada Lata
Published: July 2023

The techniques of X-ray protein crystallography, NMR and high-resolution cryo-electron microscopy have all been used to determine the high-resolution structure of proteins. The most-commonly used method, however, remains X-ray diffraction but it does rely heavily on the production of suitable crystals. Indeed, the production of diffraction quality crystals remains the rate-limiting step for most protein systems. Crystallisation trials, initiated by John Squire with the assistance of the authors, used existing and newly developed crystallisation methods for two different muscle proteins - the actin binding domain (ABD) of α-actinin and the C0-C1 domain of human cardiac myosin binding protein C (cMyBP-C). Diffracting crystals of α-actinin ABD, with a resolution of 1.9Å, however, did not prove to be in a form suitable for diffraction methods. In contrast, when the C0-C1 domain of cMyBP-C underwent proteolysis during crystallogenesis very satisfactory crystals of the C1 domain were obtained. These employed a modified hanging drop vapour diffusion method and diffracted to high resolution (1.5Å). This has led to the determination of the structure of the C1 domain of cMyBP-C at atomic resolution and has thereby provided new insights into its function.
Progress, Interrupted: American Students of Theodor Leschetizky in Vienna
Authors: Tewinkel Christiane
Published: July 2023

Musical training, for the amount of time and the diligence it takes, has often been metaphorized as a long and arduous journey, with Johann Joseph Fux’s 1725 instructional book for piano players, Gradus ad Parnassum, being a case in point. For young US American pianists at the turn of the century, the idea of instrumental training as a gradual progress toward a goal blended in with the actual experience of crossing the ocean to study with European teachers. The Vienna-based pianist Theodor Leschetizky (1830–1915) counted among the most popular teachers for American students. While no musical expedition, whether figurative or real, comes without obstacles, Leschetizky introduced a particular barrier for those interested in making a career in music. He employed assistant teachers that prepared students before they were allowed to proceed and work with him directly. This strategy turned out to be rather rewarding financially, and it also catered to fundamental concepts about artistic achievement and transatlantic relations held by the classical music scene. In this article, I will address the special appeal that Leschetizky’s gatekeeping regimen had for pianists from the United States. I will describe organizational, financial, and aesthetic implications as well as the consequences that accepting or refusing this system had for American students. In doing this, I will draw on unpublished documents from the archive of the New York Leschetizky Association and on reports from Leschetizky students and assistants.
Reviews Outside the Usual Places: Daily Newspaper Reviews of Edith Wharton in Edwardian Britain
Authors: Palmer Stephanie
Published: July 2023

The accessibility of digitized newspapers creates an opportunity to trace middlebrow taste. This article does so by analyzing how the style and substance of newspaper reviews began to diverge from magazine reviews late in the nineteenth century. Newspaper reviews became short, chatty, personal, and targeted toward the leisured reader. Self-consciously, reviewers mourned unhappy endings, complained about long factual expositions, and criticized plots on the grounds of implausibility. This shift in critical discourse is seen when comparing British newspaper and magazine reviews from the mid-nineteenth century to reviews of Edith Wharton’s early short story collections, The House of Mirth, and Ethan Frome.
An Unpublished “Family Heirloom”: Frederick William Beecher’s 1855 Williams College Journal
Authors: Diller Christopher G.
Published: July 2023

This article contextualizes selected entries from Frederick William Beecher’s unpublished 1855 journal that records his time first on vacation in Boston during winter break and then back at Williams College during the winter term. The journal is significant for literary and cultural historians and biographers, as it gives an inside glimpse into the daily life of the Beecher family and the cultural and political ferment taking place in Boston in the mid-1850s. Second, unlike other mid-century accounts of college life that were made for publication, the journal offers an unvarnished day-by-day record of the intersection of curricular and extracurricular life that illustrates the surprising autonomy of student life in a prominent liberal arts college in the years just before the Civil War. And finally, as Beecher’s journal increasingly became an intimate forum for spiritual doubt, reflection, and conversion, it provides evidence of a hitherto-undocumented religious revival at Williams in the spring of 1855.
Kritisches politisches Bewusstsein in der SEK I
Authors: Rabl Martina , Katschnig Tamara , Liegl Daniela , Schuh Sebastian
Published: July 2023

Im Lehrplan für Geschichte und Sozialkunde/Politische Bildung (GSPB) der Sekundarstufe I 2016 ist Politische Bildung erstmals in Form von Modulen verankert. Bis dahin war Politische Bil­dung für die Zielgruppe der Sekundarstufe I vor allem als fächerübergreifendes Unterrichts­prin­zip auf allen Schulstufen in Form eines Grundsatzerlasses definiert. Im Vorfeld (2008) wur­den zwar politische Kompetenzen genannt, allerdings ohne konkrete Inhalte. Aufgrund des zu­vor gültigen Lehrplans wurde ein dreijähriges Forschungsprojekt (2019–2022) an der KPH Wien/Krems mit Schwerpunkt auf den Erfahrungen der Beteiligten zur Umsetzung der Neue­run­gen zu Politischer Bildung auf der Sekundarstufe I begonnen. Im quantitativen Teil wurden das vermittelte Wissen und die Interessenslage bei Schüler*innen zu politischen Sach­ver­hal­ten erforscht. Hierfür wurden im Jahr 2019 und 2020 zwei Erhebungen durchge­führt, wo ins­ge­samt 2268 Schüler*innen an 24 Schulen in Niederösterreich mittels Fragebo­gen (paper-pen­cil) teilnahmen. Hauptkategorien waren Fachwissen anhand ausgewählter Fra­gen aus dem Be­reich der politischen Bildung, Interesse an politischem Geschehen und Einstel­lungen zu po­li­tischen Statements. Im qualitativen Teil wurden in beiden Jahren insgesamt 44 Interviews mit Lehrer*innen für GSPB geführt und die Ergebnisse Kategorien zugeordnet. Da­bei stellte sich heraus, dass sowohl bei Schüler*innen als auch bei Lehrer*innen ein stark ausgeprägtes kri­tisches politisches Bewusstsein gegeben ist, jedoch zeigen sich bei beiden Gruppen Prob­le­me bei der Umsetzung. Dies spiegelt sich auch im SDG 4 wider, wo die Forderung nach der Aus­bildung eines kritischen Bewusstseins als übergeordnetes Bildungsziel verankert ist und noch Handlungsbedarf besteht.
Mehrsprachliche Bildung als Schlüssel eines erfolgreichen Fachunterrichts am Beispiel von sprachsensiblen Aufgaben im Mathematikunterricht in der Sekundarstufe
Authors: Gilak Golriz , Müller Martina
Published: July 2023

Das Konzept der mehrsprachlichen Bildung unterstützt Lehrpersonen in der Umsetzung eines bil­dungsgerechten Unterrichts, denn Sprachförderung wird hier nicht nur auf Deutsch und den Sprachunterricht reduziert. Dieser Beitrag gewährt einen theoretischen Einblick in das Kon­zept der mehrsprachlichen Bildung am Beispiel von sprachsensiblen Aufgabenstellungen im Mathematikunterricht mit Bezug zur Mehrsprachigkeit in der Sekundarstufe. Das Ziel liegt in der Sichtbarmachung der Thematik, insbesondere für den Fachunterricht Mathematik in der Sekundarstufe. Die Erläuterungen leisten einen Beitrag zur Bedeutung von sprachfördernden Haltungen im Sinne einer schulischen Diversität, die als Normalität gelebt wird. Ebenso bieten sie eine Grundlage für neue, bedarfsgerechte Fort- und Weiterbildungen und fließen in die Ziele des SDG 4 „Hochwertige Bildung: Inklusive, gleichberechtigte und hochwertige Bildung für alle gewährleisten“ ein.
Pathways of Young Migrants in the Educational System of Lower Austria: Identifying what Works
Authors: Bachinger Almut , Braunsteiner Maria-Luise , Zarhuber Karl Johannes
Published: July 2023

This article presents the results of a study conducted at the University College of Teacher Edu­ca­tion Lower Austria in cooperation with Long Island University New York investigating the fac­tors contributing to successful educational and social integration of young migrants in schools in Lower Austria. The study seeks to explore key criteria for successful integration and in­clusion of migrants. Following a qualitative research design, data were collected in nine group discussions with migrant and non-migrant students with diverse educational back­grounds, alumni, parents, and pedagogical experts in Lower Austria. The data were analyzed the­matically. Findings of this study indicate the important role of school as educational ins­ti­tu­tion and social live world in general, the attitude of teachers in facilitating migrant youth's cul­tural integration, social capital acquisition through friendship between and within cultural groups of youth, and biculturalism and retaining own cultural identity as the most salient fac­tors for integration and successful school careers in migrant and refugee youth.
Digitalisierung als Treiber von Bildungs(un-)gerechtigkeit
Authors: Gabriel Sonja , Liebhart-Gundacker Michaela , Pecher Helmut , Römisch Barbara , Überacker Gudrun , Wallner Jasmin
Published: July 2023

Die Digitalisierung ist einerseits ein Faktor für Ungleichheiten in Bezug auf Bildung, anderer­seits aber gleichzeitig auch eine Möglichkeit der Inklusion. Diklusion – eine Kombination aus Di­gi­talisierung und Inklusion – geht genau darauf ein, wie digitale Medien den Unterricht selbst, aber auch die Schule als Organisation verändern. Ausgehend von Modellen, die den di­gital-inklusiven Unterricht ins Zentrum stellen, wird das österreichische Schulsystem be-trach­tet und jene Faktoren analysiert, die als Treiber für die Digitalisierung gelten können. Da­zu gehört vor allem der 8-Punkte-Plan, der vor allem in der Sekundarstufe I für einen in­fra¬strukturellen Schub sorgt. Allerdings sind noch weitere Faktoren für ein Gelingen der Di­klu­sion an einem Schulstandort von Bedeutung, und zwar auf der Mikro-, Meso- und Ma­kro­ebe­ne. Eine besondere Rolle kommt dabei der Schulleitung zu, die Kulturen, Strukturen und Prak­tiken der Diklusion fördern soll.
Bildungsformate für Regionalentwickler*innen
Authors: Hainfellner Elisabeth
Published: July 2023

Ein institutionenübergreifendes kompaktes Ausbildungs- oder Weiterbildungsangebot für Re­gionalentwickler*innen existiert derzeit in Österreich nicht. Die Zielsetzungen der regionalen Institutionen sind verschieden, doch sind allen das Arbeiten mit regionalen Akteur*innen in Wirtschaft und Politik sowie mit Bürger*innen gemein. Auf Basis einer Stakeholderanalyse wurden eine Gruppendiskussion mit Expert*innen auf Österreichebene sowie leitfadenge­stützte Interviews mit dreizehn Praktiker*innen aus diversen Regionen durchgeführt, um zu erheben, ob Bedarf an einem akkordierten Fortbildungsangebot besteht und wie dieses orga­nisiert sein soll. Als Ergebnis kann festgehalten werden, dass vor allem für Einsteiger*innen in dieses Berufsfeld dieser Bedarf gesehen wird. Die Konzipierung und spätere Durchführung ei­nes Bildungsangebots für Mitarbeiter*innen unterschiedlicher regionaler Institutionen wird empfohlen, ersetzt aber nicht institutionenspezifische Programme und weitere Lernformate, wie beispielsweise das Implementieren von Mentor*innen. Die Vernetzung für Regionalent­wickler*innen von unterschiedlichen Institutionen wird ebenfalls als bedeutsam erachtet, för­dert das soziale Miteinander und legt über die Grenzen von Regionen hinweg den Grundstein für eine etwaige zukünftige Zusammenarbeit.
Conservative surgical management of a heterotopic scar pregnancy: A case report
Authors: Desai Neela , Mutatkar Mukul
Published: July 2023

Introduction: The cesarean scar pregnancy is on rise and the objective of this case study is to highlight a different, bold but conservative approach to an unusual challenging case of eight weeks heterotopic cesarean scar pregnancy, which was threatening to rupture.

Case Report: A 31-year-old G3P2L1 previous two cesarean sections presented with lower abdominal pain and bleeding. She was hemodynamically stable, and ultrasonography (USG) and magnetic resonance imaging (MRI) revealed heterotopic pregnancy, eight weeks (gestational sacs > 32 mm) intrauterine and caesarean scar pregnancy, which was threatening to rupture. Since the scar pregnancy was large, BHcG was > 200,000 iu, there was evidence of imminent scar dehiscence; and she was stable and had good blood parameters. The authors decided to take cautious but bold decision of suction evacuation under USG guidance, following the uterine artery embolism. The procedure was smooth and lower segment scar sacculus bleeding was controlled by compression with help of Foley’s balloons inside uterine cavity as well as in bladder. There was no evidence of extrauterine bleeding. She made a good post-operative recovery. Follow-ups consisted of serial BHcG and USG to monitor the regress.

Conclusion: This case study implies that cesarean scar pregnancy, even with imminent scar dehiscence can be managed by USG-guided suction evacuation by experienced hands. Prior uterine artery embolization (UAE) added the safety of bleeding control. This case also emphasizes the importance of a patient monitoring and relying on failing BHcG, and a symptom free patient; and not on mass in CS scar alone which was slow to resolve.
Nefrectomía Laparoscópica Pediátrica en Honduras: Informe de los primeros 25 casos
Authors: Lizardo Barahona José R. , Godoy Murillo José Gerardo , Lizardo Wildt José Edmundo
Published: July 2023

Antecedentes: La primera nefrectomía laparoscópica en pediatría fue realizada por el Dr. Martin Koyle en un niño de 8 meses con displasia renal multiquística. En la actualidad este procedimiento es aceptado como estándar de oro para realizar cualquier nefrectomía en patología renal benigna en adultos o niños, ya que permite una mejor exposición anatómica y mejor control vascular con una estancia mas corta, menor uso de analgésicos y mejor resultado estético. Descripción de los casos clínicos: se presenta una serie de casos de nefrectomía laparoscópica comprendidas desde agosto 2001 a agosto de 2019 realizadas en el Hospital de Especialidades del Instituto Hondureño del Seguro Social localizado en el Barrio La Granja de Tegucigalpa, incluyendo en forma consecutiva todos los pacientes que ameritaron una nefrectomía programada en riñón no funcional por patología renal benigna. Durante ese periodo se diagnostican 12 displasias renales, 9 hidronefrosis obstructivas, 2 nefropatías por reflujo y 2 riñones ectópicos, de los cuales 23 fueron diagnósticos prenatales y 2 posnatales, una infección urinaria y una hipertensión. Se realizaron un total de 25 nefrectomías laparoscópicas de forma segura y exitosa sin ninguna conversión a cirugía abierta ni morbilidades. Todos los pacientes iniciaron la vía oral a las 6 horas postoperatorias y fueron dados de alta antes de completar las 24 horas intrahospitalarias. Conclusiones: La nefrectomía laparoscópica es un procedimiento seguro y exitoso en pediatría, aun cuando el tiempo operatorio es mas prolongado, permite en forma mas temprana el inicio de la vía oral alta precoz con resultados estéticos superiores.
Análisis bibliométrico de la producción científica del Dr. Antonio Vidal Mayorga (1895-1968), Revista Médica Hondureña
Authors: Alger Jackeline , Fernández Jorge A. , Javier Zepeda Carlos A.
Published: July 2023

Antecedentes: El Instituto de Enfermedades Infecciosas y Parasitología Antonio Vidal conmemora el trigésimo aniversario de su creación (1993-2023). Objetivo: Realizar un análisis bibliométrico de la producción científica del Dr. Antonio Vidal Mayorga en la Revista Médica Hondureña (RMH). Métodos: Análisis bibliométrico y revisión de alcance mediante búsquedas digitales en la Biblioteca Virtual en Salud de Honduras (https:// honduras.bvsalud.org/) y la RMH (https://revistamedicahondurena.hn/), y archivos físicos del Instituto Antonio Vidal. Los artículos fueron clasificados por tipo, año de publicación, tema específico (enfermedades transmisibles, agentes etiológicos y vectoriales, enfermedades crónicas no transmisibles, otros) y tema general (especialidades médicas, enfermedades, reseñas biográficas, actividades asistenciales y de salud pública, otros). Resultados: En los primeros 18 años de la RMH (1930-1947), el Dr. Vidal publicó 79 artículos: caso clínico 19, opinión 18, original 17, revisiones bibliográficas 11, reseñas de revistas 7 y libros 2, editoriales 5. Los años con mayor número de publicaciones fueron 1934 (10) y 1945 (16). Los temas generales con el mayor número de publicaciones fueron malaria (22) y deficiencias nutricionales (9). Se destacan sus observaciones originales con caracterizaciones clínicas, resultados de laboratorio y observaciones epidemiológicas en el campo, incluyendo observaciones entomológicas, y los artículos de opinión con propuestas sobre la organización y administración de la salud pública del país. Discusión: El Dr. Antonio Vidal Mayorga, médico y maestro ejemplar, se distingue en el contexto de la época en que vivió. Su obra fue impulsada por su capacidad de conjuntar la clínica, la epidemiología, el laboratorio, la salud pública, la investigación, la docencia y la proyección social.