bluuebunny/crossref_metadata_2025 huggingface dataset:
Shooting Simulator «Inhibitor»: Mathematical Support for Ballistics of 7.62 Caliber Weapons
Authors:   Udmurt Federal Research Center UB RAS, Egorov S. V. , Vdovin A. Y. ,   Kalashnikov ISTU, Korobeynikova I. V. ,   Kalashnikov ISTU, Petukhov K. Y. ,   Kalashnikov ISTU, Syakterev V. N. ,   Kalashnikov ISTU
Published: December 2021

The software for support of external ballistics calculation for weapons of 7.62 mm caliber is described taking into account external factors for the optical-electronic tactical exercise machine for small arms "Inhibitor" developed at the Institute of Mechanics UdmFRC UB RAS and at Computer facilities department of Kalashnikov ISTU jointly with JSC «Kalashnikov» Concern». A tactical and technical task is given for ballistic calculation of the trajectory up to 2 km of range of weapon simulators with a laser emitter of the targeting point taking into account external factors: types of sights, especially optical, ballistic scattering of bullets, deflection of the bullet from the side wind and derivation, which have a significant impact on the ballistic trajectory. The implemented differential mathematical model of external ballistics relying on the aiming angle of the weapon simulator depending on the sight readings, the initial speed and ballistic coefficient of various types of ammunition in real time builds a ballistic trajectory with adjustments for the air temperature and pressure and dependence on lateral wind and random dispersion of bullets to further solve the "problem of meeting" with obstacles. The given results of software tests for the error in calculating the coordinates of the ballistic trajectory showed full compliance with the requirements and adequacy of mathematical models. It was concluded that further research and development of electronic shooting simulators were promising thanks to the improvement of computing tools and the development of software libraries in order to increase the accuracy of simulating external ballistics of simulators taking into account many external factors, expand functional networks and reduce cost and, therefore, increase competitiveness.
Adaptation of the Risk Management System in an Industrial-Type Enterprise
Authors:   Kalashnikov ISTU, Vasilyeva N. N. , Svinov A. V. ,   IRZ TEK, Tkachuk O. V. ,   Kalashnikov ISTU
Published: December 2021

Today, little attention is paid to risks, with management focusing more on performance indicators and business results than on analyzing dangerous situations and finding new opportunities. The risk management system proposed in this paper will help to take risks under control and systematize the risk management process. Ideally, it should be integrated into the quality management system. The paper also provides a study on the development of methods for identifying, analyzing and assessing strategic risks. The risk management process is described in accordance with GOST R ISO 31000-2019; methods of risk management are considered. The risk management system included a register, a questionnaire, criteria for the severity of risk and the likelihood of occurrence, as well as a matrix of risks with a description of its zones and levels of risk. The paper provides a procedure for risk management, which describes the stages of the risk management process and their relationship with the approach proposed in GOST R ISO 31000. The standard questions of the questionnaire are formulated that will help simplify the process of identifying risks in the enterprise if the manager does not have a certain plan. A form of a risk register is proposed, which consists of successively filled columns: strategic goal, risk, qualitative risk analysis, quantitative risk assessment, risk reduction. It also describes how to fill it out and its main functions. Thus, the entire risk management system is described through its separate, but interconnected parts. With a competent approach and the integration of RMS into the QMS, risk management will give a tangible effect.
A Biometric Recognition Method Using Deep CNN
Authors: Rituraj Vishalakshi
Published: December 2021

Abstract: Face is perhaps the first biometric trait of a person that catches one’s eye and it remains in memory for a long due to its uniqueness created by almighty. Recognizing a person using his/her face, is very natural to us and we do not need any special training for identification. But computers are programmed for analyzing things and making predictions almost in similar fashion that our brain does. Then, the recognition takes place by using some techniques and trainings. The recognition system which uses biometric properties is itself a secure and trusted technique but use of neural networks make it highly accurate and add more worth to it. A CNN model works in a fully supervised or guided environment and performs all the tasks in a robotic manner. The convolutional layer which lies in CNN model performs the complex calculation and extracts all the unique and useful features without any human involvement. I preferred to adopt Transfer learning in my work, by importing a pre-trained CNN model and I found 97.5% accuracy in recognition when I tested the model with my test samples. Keywords: Biometrics, Convolution, AlexNet, Feature Extraction, Transfer Learning
A Research Paper on G-mart: The E-Commerce Website
Authors: Singh Gurpreet
Published: December 2021

Abstract: E-commerce is a boom in the modern business. E-commerce means electronic commerce. E- commerce (Electronic commerce) involves buying and selling of goods and services, or the transmitting of funds or data, over an electronic network, predominantly the Internet. E-commerce (Electronic commerce) is a paradigm shift influencing both marketers and the customers. Rather e-commerce is more than just another way to boost the existing business practices. It is leading a complete change in traditional way of doing business. This significant change in business model is witnessing a tremendous growth around the globe and India is not an exception. A massive internet penetration has added to growth of E-commerce and more particularly start-ups have been increasingly using this option as a differentiating business model. Moreover, E-Commerce has significant influences on the environment. Although the model is highly used in current business scenario but the option has not been explored at its fullest. The current research has been undertaken to describe the scenario of E-Commerce, analyze the trends of E-Commerce. The study further examines the key variables imperative for the success of E-commerce business models. Keywords: E-Commerce, Internet, Self-service, Technology, Internet banking.
AN IMPLEMENTATION OF E-LEARNING BASED MOODLE TO DEVELOP MATHEMATICAL COMMUNICATION SKILL AND SELF-EFFICACY
Authors: Astriani Linda , Setiyaningsih Dewi , Misriandi Misriandi , Yuliani Anggi
Published: December 2021

Mathematical communication skills are important, and education should facilitate students to improve their mathematical communication skills. The purpose of this study was to develop e-learning based on Moodle to improve students' mathematical communication and self-efficacy and student self-efficacy and describe how to students’ mathematic communication and student self-efficacy. This study used mixed-method research. The population in this study were Year 5 students at a private primary school. Data collection techniques used in this study are observation and tests. The implementation with Moodle was effective to the students’ mathematic communication and self-efficacy student. Overall, the students’ mathematical communication skills and self-efficacy of students using E-learning based Moodle is better than those using conventional learning. Also, self-efficacy positively affects students' communication skills with a very strong correlation coefficient, meaning that the higher students' self-efficacy, the higher students' communication skills.
Ações desenvolvidas por gerências de risco hospitalar na vigilância pós-comercialização
Authors:   Universidade Federal de Santa Catarina, Florianópolis, SC, Brasil, Danieli Schmitt Marcia , Regina de Andrade Selma ,   Universidade Federal de Santa Catarina, Florianópolis, SC, Brasil
Published: December 2021

Introdução: A qualidade insatisfatória e questionável de alguns produtos comercializados para a assistência à saúde constitui um dos problemas enfrentados pelas instituições hospitalares. Alguns hospitais contam com a gerência de risco e fazem parte da Rede Sentinela, implantada pela Agência Nacional de Vigilância Sanitária (Anvisa) para enfrentar esse problema. Objetivo: Analisar as ações desenvolvidas por gerências de risco hospitalares na vigilância pós-comercialização. Método: Estudo de casos múltiplos, com abordagem qualitativa, composto por quatro instituições hospitalares públicas integrantes da Rede Sentinela, em Florianópolis, Santa Catarina. Os dados foram coletados por meio de triangulação, com as técnicas de entrevista semiestruturada, observação direta não participante e pesquisa documental, no período de fevereiro a junho de 2017. A análise dos dados ocorreu por meio da síntese cruzada dos casos, da qual emergiram duas categorias: a estrutura organizacional da gerência de risco e as ações desenvolvidas pela gerência de risco. Resultados: Entre as similaridades nas ações realizadas pela gerência de risco hospitalar estavam o estímulo à notifcação, a investigação das notifcações, o feedback sobre a notifcação e a capacitação dos profssionais sobre a temática. Entre os principais contrastes encontrou-se a estrutura organizacional da gerência de risco em cada instituição e o processo de comunicação interna dos riscos. Conclusões: Entre as ações desenvolvidas, destaca-se o encaminhamento das notifcações para a Anvisa, via o sistema Notivisa. Essa ação é fundamental para que a agência realize a vigilância sanitária dos produtos utilizados na assistência à saúde na fase pós-comercialização.
Uma Avaliação das Notificações de Reações Adversas a Medicamentos em um Hospital Público de Minas Gerais
Authors:   Hospital Regional Antônio Dias, Fundação Hospitalar do Estado de Minas Gerais (Fhemig), Patos de Minas, MG, Brasil, Cristina de Lima Thaís , Portes de Almeida Priscila ,   Hospital Regional Antônio Dias, Fundação Hospitalar do Estado de Minas Gerais (Fhemig), Patos de Minas, MG, Brasil, Gontijo de Oliveira Rezende Dayana ,   Hospital Regional Antônio Dias, Fundação Hospitalar do Estado de Minas Gerais (Fhemig), Patos de Minas, MG, Brasil
Published: December 2021

Introdução: As reações adversas a medicamentos (RAM’s) são consideradas um grave problema de saúde pública, sendo responsáveis pelo aumento da morbimortalidade e dos custos com a saúde. Objetivo: Conhecer o perfil de ocorrência e descrever as características dos casos de RAM’s notificadas em um hospital sentinela de Minas Gerais. Método: Estudo observacional, descritivo e transversal, que utilizou como fonte a planilha de notificações de suspeita de RAM’s da gerência de risco do hospital no período de janeiro de 2015 a dezembro de 2019. Resultados: Foram analisadas 255 notificações, sendo a maioria provenientes de busca ativa (69,4%), envolvendo 269 medicamentos e 328 episódios de RAM’s. O setor com maior número de notificações foi a Clínica Médica (43,9%). A faixa etária dos pacientes mais acometidos situou-se entre 19-59 anos (54,5%), predominando o sexo masculino (50,6%) e a raça branca (54,1%). Grande parte das RAM’s manifestou-se através de distúrbios no sistema tegumentar (36,3%), com gravidade leve (63,9%), provindas principalmente do uso de anti-infecciosos sistêmicos (44,6%). Conclusão: Conclui-se que as notificações de RAM’s são recorrentes no âmbito hospitalar e o conhecimento destas permite traçar seu perfil clínico, auxiliando na prevenção das mesmas e contribuindo para maior segurança do paciente.
Alcohol abuse and the fight against it in Ufa Province in the late 19th and early 20th centuries
Authors: Migranova Elza V.
Published: December 2021

This article is a comprehensive study of issues and problems related to alcohol abuse among the population of Ufa province at the turn of the centuries. The study uses methods of statistical and comparative-historical analysis. An important source is a survey of 1913, next to archival and published sources. The questionnaire, prepared by the Commission for Combating Drunkenness at the Society for the Protection of Public Health, was distributed among the peasant population of the Ufa province. It included 30 questions and touched on various aspects related to alcohol consumption, the causes of drunkenness, and methods of combating this social evil. The analysis of the information contained in more than one and a half thousand questionnaires allowed us to conclude that the population of the agricultural villages of the Ufa province suffered from a fairly high level of alcoholization. This hypothesis is confirmed by other sources. Moreover, the Russian-speaking population was most affected by the harmful effects of alcohol; to a lesser extent, this process affected Muslim villages, including Bashkir villages. The article also describes activities to combat drunkenness on the part of the state and public organizations, which included economic, cultural, educational, sanitary, hygienic, medical and other measures, up to the declaration of the prohibition law in Russia at the beginning of World War I. The article draws conclusions about the causes of alcoholism in Ufa province in the late 19th and early 20th centuries, and attempts to give a comprehensive assessment of this phenomenon in the region at the time under consideration.
Repatriation of Polish refugees of World War I: the case of the Altai Province
Authors: Goncharov Yurii M. , Tishkina Ksenia A.
Published: December 2021

During World War I a large number of refugees evacuated to the Russian Empires periphery, such as the many Poles who were temporarily transported eastward to Siberia. This article studies their repatriation after the conflicts end, which bears some relevance to forced migration, refugees and repatriation in todays world. Based on archival and secondary sources, the authors endeavor to reconstruct the repatriation of Polish refugees from Altai province in southern Siberia. Beginning in earnest after the Soviet Unions war with Poland of 1918-21, their return was hampered by the difficult conditions of the past Civil War and the countrys economic crisis. Although an extensive network of organizations was set up to carry the repatriation out, poor communication with the center, insufficient staff and the absence of registration forms made its work extremely difficult. At the same time, many refugees returned on their own, which further complicated matters. Nevertheless, most Poles eventually made it back home. The Russian-Ukrainian-Polish Mixed Commission on Repatriation announced that its work was done in 1924, although in fact it lasted for another year.
Review of the monograph: Matiev T.Kh. The Mountain National Movement in Revolutions and the Civil War in the North Caucasus (1917–1921) (Nazran, 2020)
Authors:   Marjani Institute of History of Tatarstan Academy of Sciences, Gabdrafikova Liliya R.
Published: December 2021

This article focuses on the analysis of the monograph by T.Kh. Matiev ”Mountain national movement in revolutions and the Civil War in the North Caucasus (1917–1921)”, published in 2020 in Nazran. This study presents an original and comprehensive approach and addresses one of the most difficult cases in the history of the North Caucasus of the 20th century – the origins of the Mountain Republic. The driving force behind the idea of a federation and the protection of the rights of mountain peoples was the young intellectuals of the North Caucasus. In this regard, the reviewer sees parallels with Jadidism in the Volga-Ural region, the activity of the Tatar intellectual youth of the early 20th century, the ideas of national and cultural autonomy. The Muslim peoples of the North Caucasus and the Tatars had much in common: one religious culture, a desire for modernization from educated groups and contradictions in society. Monograph by T.Kh. Matiev shows the multiethnic world of the Russian Empire, at the same time it points to the commonality of many issues and the need for their further scientific study.
Ameloblastoma: relato de caso com recidiva extra-óssea após 32 anos
Authors: Wagner João Carlos B. , Wagner João Ephrain , Volkweis Maurício Roth , Gerhardt Eduardo , Ebling Hardy
Published: December 2021

Ameloblastoma is a benign odontogenic tumor with local, invasive growth and late recurrence. The aim of this paper is report a case with recurrence after 32 years. The patient was 52 year-old, female and presented to the Santa Casa Hospital Complex with a complain of oral swelling of 5 years duration, in the right mandibular body region. The area produced sleep apnea, mastigatory and speech problems. Microscopic exam reveled ameloblastoma with cystic degeneration and dystrophic calcification.
Considerações sobre reimplantes dentários: condutas clínicas e ortodônticas frente a estas situações
Authors: Rezende Daniela Soeiro de Souza , Ávila Márcia Delgado de , Ferreira Eduardo Silveira
Published: December 2021

Based on a literature review, the objective of this study is to establish the degree of dental analysis or root resorption that allows replanted teeth to be moved using orthodontic appliance. Some aspects of avulsion and replanted teeth such as etiology, clinical approach and prognosis are considered. It is also presented a literature review of orthodontic tooth movement. According to most authors, the replant is frequently followed by analysis that doesn't allow orthodontic movement. Nevertheless, the lack of resorption signs during a minimum period of one year allows orthodontic treatment when necessary.
Avaliação quantitativa da expressão da proteína PCNA e das AgNORs em ameloblastomas
Authors: Munerato Júlio César , Rados Pantelis Varvaki , Quadros Onofre Francisco de , Barbachan João Jorge Diniz , Filho Manoel Sant'Ana
Published: December 2021

In order to assess the proliferative behaviour of the ameloblastoma epithelium nine cases of this neoplasm were retrieved from the files of the Oral Pathology Service laboratory of Rio Grande do Sul Federal University School of Dentistry. Two proliferation marker techniques were employed: the AgNor - argyrophilic nucleolar organizer regions staining and the proliferation cell nuclear antigen (PCNA) immunohistochemical assessment technique. Each case was submitted to a quantitative and comparative statistical analysis of the results obtained for the two techniques. The conclusion arrived at shows ameloblastoma presenting benign behavior, an average AgNOR index of 1.612, and a PCNA proteindependent proliferative activity with average immunoreactivity of 51.61%. The histological patterns analyses of the neoplastic epithelial component demonstrates that cells resembling pre-ameloblasts have obtained figures statistically higher to those obtained for cells resembling the stellate reticulum of the enamel organ, in both techniques employed. Therefore, it might be inferred that cells resembling pre-ameloblasts hold the proliferative potential of ameloblastomas and are probably responsible for the growth characteristics and infiltrative ability of this tumour.
Reparo de feridas na língua de camundongos jovens e velhos
Authors: Padilha Dalva Maria Pereira , Sanfelice Júlio César , Rados Pantelis Varvaki , Bercini Francesca , Azambuja Tais Webber Furlaneto de
Published: December 2021

Ageing affects several biological structures and mechanisms. The present work studied wound healing in 2 months old and 17 months old mice. Experimental wound in the tongue of 70 mice were performed. Histological diferences or similarities in healing ofyoung and aged mice were search. The results have shown that there were no ignificative differences on wound healing between young and aged groups. It was concluded that wound healing processes at the same rate independently of group age.
Estudo comparativo de tratamento da estomatite protética pelo reembasamento ou substituição das próteses totais
Authors: Walber Luiz Fernando , Rados Pantelis Varvaki
Published: December 2021

This clinic survey aimed at comparing two different treatments for patients using full upper denture and having clinical Denture Stomatitis diagnosis. Thirty patients were selected and divided into two groups. Group I included 18 patients, whose dentures were replaced by new ones. Group II included 12 patients, whose full dentures currently used were relined. Patients were followed-up during 8 weeks. Patients of both groups were required to remove their dentures at night to be disinfected with Sodium Hypochlorite solution. The results observed show Denture Stomatitis was cured within 4 weeks in 90% the cases for both groups, showing no significant statistical differences. It may be concluded that both dentures replacement and their filling, associated to hygiene and disinfection show efficacy in Denture Stomatitis control.
Estudo comparativo entre diagnósticos radiográficos obtidos pelas técnicas interproximal e panorâmica
Authors: Dalla-Bona Reni Raymundo , Fontanella Vania , Gegler Aderson
Published: December 2021

Our pourpose was to compare the radiographic diagnostics observed in bitewing and panoramic techniques in a sample of 50 adult patients' x-rays, examined by the same observer. On the panoramic it was analyzed the area corresponding bitewings, looking for coincident diagnostics. Furthermore it was evaluated the additional information supplied by panoramic technique. The proportion of coincident diagnostics in panoramic and bitewings was significantly larger suggesting no differences between bitewings and panoramic as a diagnostic resource. When analyzing the area not inclued by bitewings on the panoramic it was found 3,72 diagnostics per patient that would request treatment or follow-up.
Efecto de un programa de educación virtual y pausas activas sobre los hábitos saludables en el personal del Recursos Humanos del Ministerio de Educación Pública durante la pandemia COVID-19
Authors: Vargas-Hernández Diana
Published: December 2021

Resumen: (1) Antecedentes: dado el contexto actual de pandemia COVID-19 y la realización de teletrabajo, se estableció como objetivo explorar la efectividad de un programa educativo sobre los hábitos de vida de las personas colaboradoras del área de Recursos Humanos (RH) del Ministerio de Educación Pública (MEP) con miras a la implementación de prácticas que lograran un mayor bienestar físico y mental. (2) Métodos: se utilizó un cuestionario elaborado con  la herramienta Google Forms. Compuesto por cinco preguntas basadas en el  Modelo Transteorético (MT) (Cabrera, 2000) y dos preguntas en el cuestionario PAR-Q & YOU (CSEP, 2002). Asimismo, se realizó una entrevista a la coordinadora de capacitaciones de recursos humanos para obtener información clave para el enfoque de la propuesta.; (3) Resultados: el género femenino fue el de mayor predominancia; cerca de esta población vive sola. Posterior a las sesiones virtuales se presentaron avances positivos en los primeros cuatro estadios de cambio del MT dado que por ejemplo, la población que estaba considerando realizar actividad física en los próximos días aumentó del 89% al 93.9%. Además, antes de la intervención, el 91.3% no presentaban complicaciones cardiovasculares y alrededor de un 40% tenían molestia articular o alguna lesión en la espalda. Resultados: esta intervención fue una oportunidad clave para motivar el cambio hacia un estilo de vida más activo y saludable en las personas colaboradoras del área de RH del MEP. (4) Conclusiones: fue oportuno realizar la intervención y mediar para un cambio positivo hacia la realización de actividad física. Además, el 72.29% confirmaron haber tenido una mejora en la salud tanto física como mental, esta última de gran relevancia en las condiciones de la pandemia actual.
Modelos de Competencias Digitales Docentes: análisis de las propuestas internacionales y nacionales más pertinentes
Authors: Castro-Granados Alejandra , Artavia-Díaz Karla Yanitzia
Published: December 2021

La creación y uso de modelos o estándares en competencias digitales docentes sucede desde hace varios años, a través de diferentes iniciativas las cuales buscan establecer criterios o normas que permitan contar con una puesta en práctica estratégica del uso de la tecnología en el ámbito pedagógico. Por lo tanto, se considera importante analizar lo desarrollado de manera reciente y que tiene un gran potencial de uso para mejorar la práctica docente en el ámbito nacional, de manera que se logre la identificación de aquellos elementos que conforman los modelos de competencias digitales existentes, que son factibles de ser considerados en la elaboración de una propuesta enfocada en el modelo educativo a distancia, abierta y en línea.
La democratización de los contratos de conservación y mantenimiento de la red vial nacional: Un caso fallido en Costa Rica
Authors: Vásquez-Rodríguez Jorge Alberto
Published: December 2021

El objetivo de esta investigación, en la que se utilizaron métodos cualitativos y cuantitativos de investigación, así como métodos cualitativos de análisis, fue determinar las causas por las cuales no fue posible, mediante la Licitación Pública No. 2014LN-000016-0CV00 MR-I: Mantenimiento Rutinario sin Maquinaria Especializada de la Red Vial Nacional Pavimentada, contratar únicamente a pequeñas y medianas empresas (Pymes) para la limpieza de hierbas y basura de la red vial nacional de Costa Rica, como pretendía la administración Chinchilla Miranda (2010-2014). El propósito del espíritu de la licitación se logró parcialmente, en tanto, las grandes empresas, dentro del marco de legalidad del país y aprovechando su infraestructura, participaron en el concurso, acaparando parte del contrato de mantenimiento vial sin maquinaria especializada de las 22 zonas en que se compone el país, para efectos de conservación y mantenimiento. Las causas principales de lo anterior fueron un marco institucional que no facilitó la contratación de las Mypmes y la licitación perdió su patrocinador en el Poder Ejecutivo. Con el cambio de gobierno, la burocracia encargada de la ejecución final de la contratación no se encontraba motivada para llevar a cabo la licitación y los micro, pequeños y medianos empresarios no contaban con los conocimientos ni la infraestructura adecuada para participar en el concurso público (licitación), aunado a los escasos recursos financieros; además de que los trabajadores que prestan el servicio directamente (peones) fueron invisibilizados de todo el proceso.
Áreas de recarga hídrica potencial en las microcuencas del distrito de Cachí, Cartago, Costa Rica
Authors: Álvarez Jiménez María , Ramírez Granados Pablo , Castro Solís José , Solís Torres Ligia
Published: December 2021

Introducción: La precipitación es la fuente más importante en las zonas recarga hídrica y para asegurar su disponibilidad y manejo es importante evaluar los cambios de uso de la tierra. Objetivo: Medir el potencial de recarga hídrica en seis microcuencas cartaginesas. Métodos: Determinamos unidades hidrogeológicas con galgas, y propiedades físicas e hidráulicas directamente en campo. Usamos curvas topográficas para generar un modelo de elevación digital y perfiles longitudinales. Además, produjimos un mapa de cambio de uso de la tierra y determinamos el balance hídrico del suelo. Resultados: El área presenta buenas condiciones hidrogeológicas en cuanto a manantiales, señalando la conexión hidráulica de las unidades, y el suelo favorece la recarga de agua en las partes altas. Arriba, donde se ubican los manantiales, la mitad del terreno tiene cobertura forestal, lo que facilita la infiltración. El resto sustenta actividades agrícolas (39% en la parte media y baja de las cuencas). Las áreas forestales presentan menores valores de recarga potencial (aprox. <611.4mm) que las áreas de cultivos y pastos (792.32-796.29mm). Conclusión: El sitio presenta buenas condiciones hidrogeológicas y las áreas de cultivos y pastos tienen valores de recarga potencial más altos que los bosques.
In vitro evaluation of BACtrack®'s smartphone-connected personal breath alcohol analyzers
Authors: Olson Aaron
Published: December 2021

This study assessed the in vitro accuracy, precision, specificity, and
measurement uncertainty of BACtrack®’s line of smartphone-connected
breath alcohol analyzers. At the 0.080 g/210L ethanol vapor
concentration the measurement uncertainty was determined to be ± 0.013,
0.004, and 0.006 g/210L for the Pro, C8, and C6 respectively at the 95%
coverage interval. The analyzers showed an apparent ethanol response to
isopropanol, and methanol, but not to acetone. BACtrack®’s
smartphone-connected breath alcohol analyzers showed the ability to
measure vaporous ethanol with confidence in the results.
Experimental study on fracture properties of dam concrete under post-peak cyclic loading based on DIC and acoustic emission techniques
Authors: Bu Jingwu , Xu Huiying , Wu Xinyu , Chen Xudong , Xu Bo
Published: December 2021

In order to study the fracture properties of dam concrete under
post-peak cyclic loading, wedge splitting tests with three loading rates
(0.001 mm/s, 0.01 mm/s, 0.1 mm/s) were performed on notched cubic dam
concrete specimens. Meanwhile, the acoustic emission (AE) and digital
image correlation (DIC) technologies were used to record the crack
propagation process of specimens. Test results show that the fracture of
dam concrete has a significant rate effect: with the loading rate
increases, the peak load increases, the slope of the post-peak P-CMOD
curve gradually decreases and the stiffness degradation of dam concrete
becomes more serious. The cumulative AE count shows a step increasing
trend and has a Kaiser effect. The Kaiser effect decreases with the
post-peak cyclic loading procedure, and with the loading rate increases,
the Kaiser effect increases. With the increasing of loading rate, AE
energy fluctuates violently and b value fluctuates frequently,
indicating the damage of dam concrete becomes more serious. As the
loading procedure, the damage of the specimen accumulates gradually, and
the strain recovery rate decreases gradually. With the loading rate
increases, the strain recovery rate decreases and the permanent crack
increases. Based on the fictitious crack model, the effective crack
length shows a gradual and steady rising trend. As the loading rate
increases, the growth rate of the effective crack length becomes large.
Fatigue damage and life evaluation of thick bi-material double strap joints for use in marine applications
Authors: Kumar Rahul Iyer , Jaiswal Pankaj , Waele Wim De
Published: December 2021

The present-day interest in the use of composite-steel joints in primary
marine applications requires an in-depth knowledge of the fatigue
performance of thick adhesive joints. This paper reports on experimental
tests, quasi-static and fatigue, performed on unaged and aged
bi-material double strap joints with thick adhesive bondlines. The
specimens are monitored by Digital Image Correlation and Infrared
Thermography techniques to evaluate the types and extent of damage that
occur in the joint during fatigue loading. The S-N curve of the aged
joint is evaluated along with it’s fatigue limit. It is found that the
unaged specimens fail due to cohesive damage, hackles and disbond at the
adhesive-adherend interface and the aged specimens failed due to
delamination within the composite. The specimens that survived fatigue
loading showed similar residual strength as specimens that were not
fatigue loaded.
Experience of Combined Procedure During Percutaneous Left Atrial Appendage Closure.
Authors: Domain Guillaume , Dognin Nicolas , O'Hara Gilles , Rodes-Cabau Josep , Paradis Jean-Michel , Strubé Camille , Bernier Mathieu , OConnor Kim , Beaudoin Jonathan , Philippon François , Salaun Erwan , Champagne Jean
Published: December 2021

Introduction: Percutaneous left atrial appendage closure (LAAC) is an
alternative to oral anticoagulant (OAC) in patients with non-valvular
atrial fibrillation (AF) and contraindication to long-term OAC. Combined
strategy with percutaneous LAAC at the same time of other cardiac
structural or electrophysiological procedure has emerged as an
alternative to staged strategy. Aim: To describe our experience of
combined LAAC procedures using Watchman™ devices. Method: All patients
with combined LAAC procedure using Watchman™ (WN) devices performed from
2016-2021 were included. The primary safety endpoint was a composite of
periprocedural complications and adverse events during follow-up. The
primary efficacy endpoint included strokes, systemic embolisms, major
bleeding, and cardiovascular death. Results: Since 2016, among the 157
patients who underwent LAAC using WN devices, 16 underwent a combined
strategy: 6 TEMVR (37%), 6 typical atrial flutter ablation (37%), 2 LP
implantation (13%) and 2 atrial fibrillation ablation (13%). The WN
device was successfully implanted in 98% and 100% for single and
combined LAAC respectively (p = 0.63). Median follow-up was 13 months
(IQR 25/75 3/24) in the whole cohort. Device related complications
occurred in 6 out of 141 patients (4%) who underwent single LAAC and in
no (0/16) patient in the combined LAAC procedure (p=ns). The procedural
related complications did not differ significantly between groups (5%
vs 12%, respectively in the single and combined group, p=0.1).
Conclusion: Combined procedure combining LAAC using the Watchman™
devices and one other structural or electrophysiological procedure is
safe and effective. Larger series are needed to confirm these results.
Computational modelling to predict mechanosensing of fibroblast cells in response to different material properties
Authors: Yang Wenjian , Luo Ma , Gao Yanfei , Chen Jinju
Published: December 2021

We present a computational model of the mechanosensing of a fibroblast
cell seeded on the materials with different stiffnesses and thicknesses.
The model can predict the critical thickness of a given biomaterial that
a cell can sense and the dynamic change of stress fibres and focal
adhesions through its incorporation of the dynamic characteristics of
stress fibre contraction and focal adhesion. We show that the cell-cell
communication via elastic substrate induces the orientation of stress
fibres. The cell-cell interaction through compliant substrate has a
small but significant effect on enhancing the cell depth sensing
capability in terms of interfacial displacement and stress fibre
concentration. The framework developed here is important for a thorough
understanding of processes where substrates are deformed such as in
wound healing process and the design of bioactive coatings for tissue
engineering.
Water table depth prediction based on Deep learning models in Electrical Power Transmission Lines area
Authors: Wang Shijun , Ping Chang , Wang Ning , Wen Jing , Zhang Ke , Yuan Kun , Yang Jun
Published: December 2021

Background: Predicting water table depth in Electrical Power
Transmission Lines area presents great importance and helps the decision
makers do the safety analysis during the project. The present study
predicts the water table depth with observed weather data and hydrologic
data. Method: The study first compared the results of LSTM, GRU,
LSTM-S2S, and FFNN models in daily data simulation. Moreover, two
scenarios (S1 and S2) were set to identify the effect of the water
component on water table depth simulation. In addition, in order to
analyze how data time scale influences the model simulation results, the
monthly scale data was simulated by LSTM, GRU, and LSTM-S2S models.
Result: The result indicated that LSTM-S2S was the best model for
predicting daily water table depth among the four models. By contrast,
FFNN performed the worst. LSTM and GRU model performed equally well both
in daily data and monthly data simulation. S1 performed better than S2
in the water table depth simulation. The average daily performance of R2
and NSE was both higher than that in the monthly results with LSTM, GRU,
and LSTM-S2S models. Conclusion: As a result, the method in the present
study can be used to simulate the water table depth in the future in
Electrical Power Transmission Lines area.
Just war theory in Njegos’s works
Authors: Stanar Dragan
Published: December 2021

Modern just war theory represents more of a tradition of thoughts on ethical
issues of war than a theory per se. However, philosophical attitudes on war
coming from authors from non-western cultures, including Serbian culture,
are often left outside of this tradition. Author aims to demonstrate that
there are clear ideas on ethical attributes of war and warring in Njegos?s
work. By analyzing Njegos?s views expressed in his most significant works,
through the prism of criteria of the classical elements of the modern just
war theory (Jus ad Bellum, Jus in Bello), author demonstrates the existence
of Serbian tradition of thought on ethics of war and warring. In this way,
modern just war theory is supplemented and enriched with the Serbian
historical perspective on justness of war and in war. Simultaneously, author
highlights the challenges and perils of interpretation of philosophical
ideas without considering the historical context, specific
political-culturological circumstances and personality of the idea author.
This is of a particular contemporary relevance, as misinterpretations of
Njegos?s ideas on war and justice in war are often used to further fuel
national antagonisms and destabilize the region.
Index60 Identifies Individuals at Appreciable Risk for Stage 3 Among an Autoantibody-Positive Population With Normal 2-Hour Glucose Levels: Implications for Current Staging Criteria of Type 1 Diabetes
Authors: Nathan Brandon M. , Redondo Maria J. , Ismail Heba , Jacobsen Laura , Sims Emily K. , Palmer Jerry , Skyler Jay , Bocchino Laura , Geyer Susan , Sosenko Jay M.
Published: December 2021

OBJECTIVE

We assessed whether Index60, a composite measure of fasting C-peptide, 60-min C-peptide, and 60-min glucose, could improve the metabolic staging of type 1 diabetes for progression to clinical disease (stage 3) among autoantibody-positive (Ab+) individuals with normal 2-h glucose values (<140 mg/dL).

RESEARCH DESIGN AND METHODS

We analyzed 3,058 Type 1 Diabetes TrialNet Pathway to Prevention participants with 2-h glucose <140 mg/dL and Index60 <1.00 values from baseline oral glucose tolerance tests. Characteristics associated with type 1 diabetes (younger age, greater Ab+, higher HLA DR3-DQ2/DR4-DQ8 prevalence, and lower C-peptide) were compared among four mutually exclusive groups: top 2-h glucose quartile only (HI-2HGLU), top Index60 quartile only (HI-IND60), both top quartiles (HI-BOTH), and neither top quartile (LO-BOTH). Additionally, within the 2-h glucose distribution of <140 mg/dL and separately within the Index60 <1.00 distribution, comparisons were made between those above or below the medians.

RESULTS

HI-IND60 and HI-BOTH were younger, with greater frequency of more than two Ab+, and lower C-peptide levels, than either HI-2HGLU or LO-BOTH (all P < 0.001). The cumulative incidence for stage 3 was greater for HI-IND60 and HI-BOTH than for either HI-2HGLU or LO-BOTH (all P < 0.001). Those with Index60 values above the median were younger and had higher frequency of two or more Ab+ (P < 0.001) and DR3-DQ2/DR4-DQ8 prevalence (P < 0.001) and lower area under the curve (AUC) C-peptide levels (P < 0.001) than those below. Those above the 2-h glucose median had higher AUC C-peptide levels (P < 0.001), but otherwise did not differ from those below.

CONCLUSIONS

Index60 identifies individuals with characteristics of type 1 diabetes at appreciable risk for progression who would otherwise be missed by 2-h glucose staging criteria.
Association Between the ACE Insertion/Deletion Polymorphism and Risk of Lower-Limb Amputation in Patients With Long-Standing Type 1 Diabetes
Authors: Mohammedi Kamel , Abouleka Yawa , Carpentier Charlyne , Potier Louis , Dubois Severine , Foussard Ninon , Rigalleau Vincent , Gautier Jean-François , Gourdy Pierre , Charpentier Guillaume , Roussel Ronan , Scheen André , Bauduceau Bernard , Hadjadj Samy , Alhenc-Gelas François , Marre Michel , Velho Gilberto
Published: December 2021

OBJECTIVE

The ACE insertion/deletion (I/D) polymorphism has been widely studied in people with diabetes, albeit not with regard to lower-limb amputation (LLA). We examined associations among this polymorphism, plasma ACE concentration, and LLA in people with type 1 diabetes.

RESEARCH DESIGN AND METHODS

ACE I/D genotype and plasma ACE were assessed in three prospective cohorts of participants with type 1 diabetes. LLA was defined as minor (below-the-ankle amputation consisting of at least one ray metatarsal resection) or major (transtibial or transfemoral) amputation. Linear, logistic, and Cox regression models were computed to evaluate the likelihood of prevalent and incident LLA by ACE genotype (XD [ID or ID] vs. II) and plasma ACE, after adjusting for confounders.

RESULTS

Among 1,301 participants (male 54%, age 41 ± 13 years), 90 (6.9%) had a baseline history of LLA. Baseline LLA was more prevalent in XD (7.4%) than in II genotype (4.5%, odds ratio [OR] 2.17 [95 %CI 1.03–4.60]). Incident LLA occurred in 53 individuals during the 14-year follow-up and was higher in XD versus II carriers (hazard ratio 3.26 [95% CI 1.16–13.67]). This association was driven by excess risk of minor, but not major, LLA. The D allele was associated with increased prevalent LLA at the end of follow-up (OR 2.48 [1.33–4.65]). LLA was associated with higher mean (95% CI) ACE levels in II (449 [360, 539] vs. 354 [286, 423] ng/mL), but not XD (512 [454, 570] vs. 537 [488, 586]), carriers.

CONCLUSIONS

This report is the first of an independent association between ACE D allele and excess LLA risk, mainly minor amputations, in patients with type 1 diabetes.
Association Between the ACE Insertion/Deletion Polymorphism and Risk of Lower-Limb Amputation in Patients With Long-Standing Type 1 Diabetes
Authors: Mohammedi Kamel , Abouleka Yawa , Carpentier Charlyne , Potier Louis , Dubois Severine , Foussard Ninon , Rigalleau Vincent , Gautier Jean-François , Gourdy Pierre , Charpentier Guillaume , Roussel Ronan , Scheen André , Bauduceau Bernard , Hadjadj Samy , Alhenc-Gelas François , Marre Michel , Velho Gilberto
Published: December 2021

OBJECTIVE. The ACE insertion/deletion
(I/D) polymorphism has been widely studied in people with diabetes, albeit not
regarding lower-limb amputation (LLA). We examined associations between this
polymorphism, plasma ACE concentration and LLA in people with type 1 diabetes.

RESEARCH DESIGN AND METHODS. ACE I/D genotype and plasma ACE were
assessed in three prospective cohorts of participants with type 1 diabetes. LLA
was defined as minor (below the ankle amputation consisting of at
least 1-ray metatarsal
resection) or major (transtibial or
transfemoral) amputation. Linear, logistic and Cox
regression models were computed to evaluate the likelihood of prevalent and
incident LLA by ACE genotype (XD [ID or ID] versus II) and plasma ACE,
after adjusting for confounders.

RESULTS. Among 1301 participants (male 54%, age 41±13 years), 90
(6.9%) participants had a baseline history of LLA. Baseline LLA was more
prevalent in XD (7.4%) than in II genotype (4.5%): OR 2.17 (95%CI, 1.03–4.60). Incident LLA occurred
in 53 individuals during 14-year follow-up. It was higher in XD versus II carriers: HR 3.26
(1.16–13.67).
This association was driven by excess risk of minor,
but not major, LLA. The D-allele was associated with increased prevalent LLA at the end of
follow-up (OR 2.48 [1.33–4.65]). LLA was associated with higher ACE levels in II (449 [360–539]
versus 354 [286–423] ng/ml), but not in XD carriers (512 [454–570] versus 537
[488–586]).

CONCLUSIONS. This is the first report of an independent
association between ACE D-allele and excess LLA risk, mainly minor amputations, in patients with type 1 diabetes.
Tecnologías biofloc y recirculación de agua en crianza de vieja azul (Andinoacara rivulatus)
Authors: Medina Villacís Marlene , Espinoza Guerra Italo , Varela Bravo Esperanza del Pilar
Published: December 2021

Objetivo: Determinar el efecto de tecnologías biofloc y recirculación de agua (RAS) aplicadas en crianza de Vieja azul (Andinoacara rivulatus), realizado en el Programa de Piscicultura del Campus Experimental “La María”, UTEQ. Tratamientos: Se aplicó un diseño completamente al azar (DCA), con arreglo bifactorial de 2x2 como factor A las tecnologías (Biofloc y RAS), factor B densidad (D1 y D2), con cuatro tratamientos y cinco repeticiones, en los tratamientos T1D1 se introdujeron (8) unidades experimentales y en los tratamientos T2D2 10 peces por repetición, total 180 alevines, con peso promedio inicial de 7,80 g. Los resultados fueron sometidos a prueba de Tukey (p<0,05), se midieron parámetros zootécnicos de ganancia de peso (g), conversión alimenticia, tasa de crecimiento absoluto (TCA), porcentaje de crecimiento (SUP), además de parámetros del agua como pH, oxígeno, temperatura y turbidez. Resultados:  Ganancia de peso fueron mayores para T1 Biofloc, con (17,51 g) y con respecto de RAS una ganancia de (17,44 g) no existiendo diferencia significativa, para conversión alimenticia no presentó diferencia estadística, pero si numérica,  siendo mayor para la tecnología  T1 (4,25 g), la mayor conversión alimenticia se obtuvo con D2 (4,06 g) y en la relación tecnología*densidad, presentó mayor conversión alimenticia el T1D2 (4,26 g), seguido por T1D1 (4,24 g), por el T2D2 (3,85 g) y por el  T2D1 (3,78 g) siendo esta relación de menor conversión alimenticia. En supervivencia se obtuvo para T2D1 (77,50%), por T1D2 (70,00%) y por T2D2 (68,00%) siendo esta última de menor tasa de crecimiento. Conclusiones: Las tecnologías y densidades no tienen efecto en el desempeño zootécnico.
Reservorio ileal resultados funcionales
Authors: Cedeño Ruíz Andrés Eduardo
Published: December 2021

Objetivo: Presentar la experiencia y resultados de corto plazo del Reservorio Ileal y Anastomosis Reservorio ileo-anal (RIARA) en “J” luego de proctocolectomía  en el  manejo de Colitis Ulcerosa (CU) y Poliposis Adenomatosa Familiar (PAF).Métodos: Revisión de los expedientes clínicos de una serie de casos manejados con RIARA reclutados entre 2014 y 2016.Resultados: Se incluyeron 11 casos  (8 hombres y 3 mujeres), de los cuales 8 casos tenían PAF y 3 CU. La edad media fue de 45 años. Se  encontró  absceso pélvico en tres casos y en uno  incontinencia anal a líquidos de manera temporal. Sólo 1 caso requirió  re-intervención quirúrgica. La media de estancia hospitalaria fue de 11.9 días con un número de 5  evacuaciones en 24 horas a los tres meses.  No hubo muertes en la serie.Conclusiones: Los resultados de esta serie demuestran adecuada calidad de vida y buenos resultados funcionales, morbilidad aceptable y sin mortalidad. Es necesario el seguimiento a largo plazo para identificar complicaciones tardías.