bluuebunny/crossref_metadata_2025 huggingface dataset:
Emulsion Structural Remodeling in Milk and Its Gelling Products: A Review
Authors: Yao Dexing , Sun Le-Chang , Zhang Ling-Jing , Chen Yu-Lei , Miao Song , Cao Ming-Jie , Lin Duanquan
Published: October 2024

The fat covered by fat globule membrane is scattered in a water phase rich in lactose and milky protein, forming the original emulsion structure of milk. In order to develop low-fat milk products with good performance or dairy products with nutritional reinforcement, the original emulsion structure of milk can be restructured. According to the type of lipid and emulsion structure in milk, the remolded emulsion structure can be divided into three types: restructured single emulsion structure, mixed emulsion structure, and double emulsion structure. The restructured single emulsion structure refers to the introduction of another kind of lipid to skim milk, and the mixed emulsion structure refers to adding another type of oil or oil-in-water (O/W) emulsion to milk containing certain levels of milk fat, whose final emulsion structure is still O/W emulsion. In contrast, the double emulsion structure of milk is a more complicated structural remodeling method, which is usually performed by introducing W/O emulsion into skim milk (W2) to obtain milk containing (water-in-oil-in-water) W1/O/W2 emulsion structure in order to encapsulate more diverse nutrients. Causal statistical analysis was used in this review, based on previous studies on remodeling the emulsion structures in milk and its gelling products. In addition, some common processing technologies (including heat treatment, high-pressure treatment, homogenization, ultrasonic treatment, micro-fluidization, freezing and membrane emulsification) may also have a certain impact on the microstructure and properties of milk and its gelling products with four different emulsion structures. These processing technologies can change the size of the dispersed phase of milk, the composition and structure of the interfacial layer, and the composition and morphology of the aqueous phase substance, so as to regulate the shelf-life, stability, and sensory properties of the final milk products. This research on the restructuring of the emulsion structure of milk is not only a cutting-edge topic in the field of food science, but also a powerful driving force in promoting the transformation and upgrading of the dairy industry to achieve high-quality and multi-functional dairy products, in order to meet the diversified needs of consumers for health and taste.
Research Progress on Genomic Regions and Candidate Genes Related to Milk Composition Traits of Dairy Goats Based on Functional Genomics: A Narrative Review
Authors: Yang Xu , Li Qing , Wang Yanyan , Wang Jianmin , Hu Jiaqing , Ji Zhibin , Chao Tianle
Published: October 2024

Background: Goat milk has gained global attention for its unique nutritional properties and potential health benefits. Advancements in functional genomic technologies have significantly progressed genetic research on milk composition traits in dairy goats. Results: This review summarizes various research methodologies applied in this field. Genome-wide association studies (GWAS) have identified genomic regions associated with major milk components, with the diacylglycerol acyltransferase 1 (DGAT1) gene and casein gene cluster consistently linked to milk composition traits. Transcriptomics has revealed gene expression patterns in mammary tissue across lactation stages, while the role of non-coding RNAs (such as miRNAs and circRNAs) in regulating milk composition has been confirmed. Proteomic and metabolomic studies have not only helped us gain a more comprehensive understanding of goat milk composition characteristics but have also provided crucial support for the functional validation of genes related to milk components. The integration of multi-omics data has emerged as an effective strategy for elucidating complex regulatory networks from a systems biology perspective. Conclusions: Despite progress, challenges remain, including refining reference genomes, collecting large-scale phenotypic data, and conducting functional validations. Future research should focus on improving reference genomes, expanding study populations, investigating functional milk components, exploring epigenetic regulation and non-coding RNAs, and studying microbiome–host genome interactions. These efforts will inform more precise genomic and marker-assisted selection strategies, advancing genetic improvements in milk composition traits in dairy goats.
Polymorphic Loci of Adaptively Significant Genes Selection for Determining Nucleotide Polymorphism of Pinus sylvestris L. Populations in the Urals
Authors: Chertov Nikita , Sboeva Yana , Nechaeva Yulia , Boronnikova Svetlana , Zhulanov Andrei , Pechenkina Victoria , Kalendar Ruslan
Published: October 2024

Background: Scots Pine is one of the main forest-forming species in boreal forests; it has great economic and ecological significance. This study aimed to develop and test primers for detecting nucleotide polymorphisms in genes that are promising for detecting adaptive genetic variability in populations of Pinus sylvestris in the Urals and adjacent territories. Objectives: The objects of the study were 13 populations of Scots Pine located in the Perm Territory, Chelyabinsk Region, and the Republic of Bashkortostan. Results: Sixteen pairs of primers to loci of potentially adaptively significant genes were developed, from which three pairs of primers were selected to detect the nucleotide diversity of the studied populations. The indicator of total haplotype diversity determined in the three studied loci varied from 0.620 (Pinus-12 locus) to 0.737 (Pinus-11 locus) and, on average, amounted to 0.662. The nucleotide diversity indicators in P. sylvestris in the study region were, on average, low (π = 0.004, θW = 0.013). Their highest values were found at the Pinus-12 locus (π = 0.005; θW = 0.032), and the lowest were found at the Pinus-15 locus (π = 0.003; θW = 0.002). This indicates that Pinus-15 is the most conserved of the three studied loci. In the three studied P. sylvestris loci associated with adaptation to environmental factors, 97 polymorphic positions were identified. The 13 populations of P. sylvestris are characterized by an average level of genetic diversity (Hd = 0.662; π = 0.004; θ = 0.013). Conclusions: The polymorphic loci of adaptively significant genes of P. sylvestris can help identify the adaptive potential of pine forests in conditions of increasing ambient temperatures.
FIG4-Related Parkinsonism and the Particularities of the I41T Mutation: A Review of the Literature
Authors: Boura Iro , Giannopoulou Irene Areti , Pavlaki Vasiliki , Xiromerisiou Georgia , Mitsias Panayiotis , Spanaki Cleanthe
Published: October 2024

Background/Objectives: The genetic underpinnings of Parkinson’s disease (PD) and parkinsonism have drawn increasing attention in recent years. Mutations in the Factor-Induced Gene 4 (FIG4) have been implicated in various neurological disorders, including Charcot-Marie-Tooth disease type 4J (CMT4J), amyotrophic lateral sclerosis (ALS), and Yunis-Varón syndrome. This review aims to explore the association between FIG4 mutations and parkinsonism, with a specific focus on the rare missense mutation p.Ile41Thr (I41T). Methods: We identified 12 cases from 10 different families in which parkinsonism was reported in conjunction with CMT4J polyneuropathy. All cases involved the I41T mutation in a compound heterozygous state, combined with a FIG4 loss-of-function mutation. Data from clinical observations, neuroimaging studies, and genetic analyses were evaluated to understand the characteristics of parkinsonism in these patients. Results: In all 12 cases, parkinsonism developed either concurrently or following the onset of CMT4J neuropathy, but was never observed in isolation. Cases of both early- and late-onset parkinsonism were identified, reflecting similarities to genetic forms of parkinsonism with autosomal recessive inheritance. Imaging studies, including Dopamine transporter Single Photon Emission Computed Tomography (DaTscan) and brain magnetic resonance imaging (MRI), revealed abnormalities indicative of neurodegeneration, consistent with findings in other neurodegenerative disorders. Conclusions: The co-occurrence of parkinsonism with CMT4J in patients carrying the I41T mutation suggests an expanded spectrum of FIG4-related disorders, potentially implicating the same molecular mechanisms seen in other neurodegenerative disorders. Further research into FIG4-mediated pathways may offer valuable insights into potential therapeutic targets for disorders of both the central and peripheral nervous systems.
Transcriptomic Analysis of Hippocampus abdominalis Larvae Under High Temperature Stress
Authors: Xiao Wenjie , Guo Baoying , Tan Jie , Liu Changlin , Jiang Da , Yu Hao , Geng Zhen
Published: October 2024

Objectives: Acute temperature stress was explored in Hippocampus abdominalis through a comprehensive RNA-seq analysis. Methods: RNA-seq was conducted on 20-day-old H. abdominalis after 24 h of temperature stress. Four experimental conditions were established: a control group (18 °C) and three temperature treatment groups (21, 24, and 27 °C). Results: Seahorse larvae were found to be unaffected by 21 °C and 24 °C and were able to survive for short periods of time during 24 h of incubation, whereas mortality approached 50% at 27 °C. The sequencing process produced 75.63 Gb of high-quality clean data, with Q20 and Q30 base percentages surpassing 98% and 96%, respectively. A total of 141, 333, and 1598 differentially expressed genes were identified in the 21, 24, and 27 °C groups vs. a control comparison group, respectively. Notably, the number of up-regulated genes was consistently higher than that of down-regulated genes across all comparisons. Gene Ontology functional annotation revealed that differentially expressed genes were predominantly associated with metabolic processes, redox reactions, and biosynthetic functions. In-depth KEGG pathway enrichment analysis demonstrated that down-regulated genes were significantly enriched in pathways related to steroid biosynthesis, terpenoid backbone biosynthesis, spliceosome function, and DNA replication. Up-regulated genes were enriched in pathways associated with the FoxO signaling pathway and mitophagy (animal). The results indicated that temperature stress induced extensive changes in gene expression in H. abdominalis, involving crucial biological processes such as growth, biosynthesis, and energy metabolism. Conclusions: This study provided key molecular mechanisms in the response of H. abdominalis to temperature stress, offering a strong basis for future research aimed at understanding and mitigating the effects of environmental stressors on marine species.
ILMCNet: A Deep Neural Network Model That Uses PLM to Process Features and Employs CRF to Predict Protein Secondary Structure
Authors: Dong Benzhi , Su Hui , Xu Dali , Hou Chang , Liu Zheng , Niu Na , Wang Guohua
Published: October 2024

Background: Protein secondary structure prediction (PSSP) is a critical task in computational biology, pivotal for understanding protein function and advancing medical diagnostics. Recently, approaches that integrate multiple amino acid sequence features have gained significant attention in PSSP research. Objectives: We aim to automatically extract additional features represented by evolutionary information from a large number of sequences while simultaneously incorporating positional information for more comprehensive sequence features. Additionally, we consider the interdependence between secondary structures during the prediction stage. Methods: To this end, we propose a deep neural network model, ILMCNet, which utilizes a language model and Conditional Random Field (CRF). Protein language models (PLMs) pre-trained on sequences from multiple large databases can provide sequence features that incorporate evolutionary information. ILMCNet uses positional encoding to ensure that the input features include positional information. To better utilize these features, we propose a hybrid network architecture that employs a Transformer Encoder to enhance features and integrates a feature extraction module combining a Convolutional Neural Network (CNN) with a Bidirectional Long Short-Term Memory Network (BiLSTM). This design enables deep extraction of localized features while capturing global bidirectional information. In the prediction stage, ILMCNet employs CRF to capture the interdependencies between secondary structures. Results: Experimental results on benchmark datasets such as CB513, TS115, NEW364, CASP11, and CASP12 demonstrate that the prediction performance of our method surpasses that of comparable approaches. Conclusions: This study proposes a new approach to PSSP research and is expected to play an important role in other protein-related research fields, such as protein tertiary structure prediction.
Ductile Versus Brittle Tectonics in the Anatolian–Aegean–Balkan System
Authors: Mantovani Enzo , Viti Marcello , Babbucci Daniele , Tamburelli Caterina , Baglione Massimo , D’Intinosante Vittorio
Published: October 2024

It is hypothesized that the present tectonic setting of the Anatolian, Aegean and Balkan regions has been deeply influenced by the different deformation styles of the inner and outer belts which constituted the Oligocene Tethyan system. Stressed by the Arabian indenter, this buoyant structure has undergone a westward escape and strong bending. The available evidence suggests that in the Plio–Pleistocene time frame, the inner metamorphic core mainly deformed without undergoing major fragmentations, whereas the orogenic belts which flanked that core (Pontides, Balkanides, Dinarides and Hellenides) behaved as mainly brittle structures, undergoing marked fractures and fragmentations. This view can plausibly explain the formation of the Eastern (Crete–Rhodes) and Western (Peloponnesus) Hellenic Arcs, the peculiar time-space features of the Cretan basins, the development of the Cyprus Arc, the North Aegean strike-slip fault system, the southward escapes of the Antalya and Peloponnesus wedges and the complex tectonic setting in the Balkan zone. These tectonic processes have mostly developed since the late Late Miocene, in response to the collision of the Tethyan belt with the Adriatic continental domain, which accelerated the southward bending of the Anatolian and Aegean sectors, at the expense of the Levantine and Ionian oceanic domains. The proposed interpretation may help us to understand the connection between the ongoing tectonic processes and the spatio-temporal distribution of major earthquakes, increasing the chances of estimating the long-term seismic hazard in the study area. In particular, it is suggested that seismic activity in the Serbo–Macedonian zone may be favored by the post-seismic relaxation that develops after seismic crises in the Epirus thrust front and inhibited/delayed by the activations of the North Anatolian fault system.
Identifying Potential Landslides in Low-Coherence Areas Using SBAS-InSAR: A Case Study of Ninghai County, China
Authors: Xu Jin , Ge Shijie , Zhuang Chunji , Bai Xixuan , Gu Jianfeng , Zhang Bingqiang
Published: October 2024

The southeastern coastal regions of China are characterized by typical hilly terrain with abundant rainfall throughout the year, leading to frequent geological hazards. To investigate the measurement accuracy of surface deformation and the effectiveness of error correction methods using the small baselines subset–interferometry synthetic aperture radar (SBAS-InSAR) method in identifying potential geological hazards in such areas, this study processes and analyzes 129 SAR images covering Ninghai County, China. By processing coherence coefficients using the Stacking technique, errors introduced by low-coherence images during phase unwrapping are mitigated. Subsequently, interferograms with high coherence are selected for time-series deformation analysis based on the statistical parameters of coherence coefficients. The results indicate that, after mitigating errors from low-coherence images, applying the SBAS-InSAR method to only high-coherence SAR datasets provides reliable surface deformation results. Additionally, when combined with field geological survey data, this method successfully identified landslide boundaries and potential landslides not accurately detected in previous geological surveys. This study demonstrates that using the SBAS-InSAR method and selecting high-coherence SAR images based on interferogram coherence statistical parameters significantly improves measurement accuracy and effectively identifies potential geological hazards.
Effects of CO2 on the Mechanical Properties of Hanna Sandstone
Authors: Dabbaghi Ehsan , Ng Kam
Published: October 2024

Possible deterioration of a rock’s structure and mechanical properties due to chemical reactions between the host rock, formation water, and CO2 requires due attention. In this study, cylindrical sandstone specimens obtained from the Hanna Formation, Wyoming, were prepared under three treatment conditions: dry, submerged in water, and treated with water + CO2 for one week at a pressure of 5 MPa and room temperature. Specimens were subjected to three effective confining pressures of 5, 15, and 25 MPa. The mechanical test results show that water + CO2 treatment, on average, decreases the peak strength and elastic modulus of the specimens by 36% and 20%, respectively, compared to dry specimens. For all three effective confining pressures, the dry specimens exhibited higher compressive strengths, larger Young’s moduli, and more brittle behavior. CO2-treated specimens showed significantly lower calcite contents.
Identifying Elements for a Cardiac Rehabilitation Program for Caregivers: An International Delphi Consensus
Authors: Loureiro Maria , Duarte João , Mendes Eugénia , Oliveira Isabel , Coutinho Gonçalo , Martins Maria Manuela , Novo André
Published: October 2024

Background/Objectives: Caregivers of patients with heart disease may often feel physically, emotionally, and psychologically overwhelmed by their role. The analysis of cardiac rehabilitation (CR) components and caregivers’ needs suggests that some interventions may benefit them. Therefore, this study aimed to identify a consensus on the CR components targeting caregivers of patients with heart disease. Methods: A three-round international e-Delphi study with experts on CR was conducted. In round 1, experts provided an electronic level of agreement on a set of initial recommendations originating from a previous scoping review. In round 2, experts were asked to re-rate the same items after feedback and summary data were provided from round 1. In round 3, the same experts were asked to re-rate items that did not reach a consensus from round 2. Results: A total of 57 experts were contacted via e-mail to participate in the Delphi panel, and 43 participated. The final version presents seven recommendations for caregivers of patients with heart disease in CR programs. Conclusions: These recommendations are an overview of the evidence and represent a tool for professionals to adapt to their context in the different stages of CR, integrating the caregiver as a care focus and as support for their sick family members. By identifying the components/interventions, there is potential to benchmark the development of a cardiac rehabilitation strategy to be used and tested by the healthcare team for optimizing the health and role of these caregivers.
Barriers and Willingness to Continue Using Telehealth Services Beyond the COVID-19 Pandemic from the Perspectives of Oral and Maxillofacial Surgeons in Australia: A Mixed-Method Study
Authors: Masongo Chipampe , Daire Judith , Estai Mohamed , Gebauer Dieter , Smith Leon , Chih HuiJun
Published: October 2024

Background: Patient demand for oral and maxillofacial telehealth services increased during COVID-19. To explore the potential for their continued use post-COVID-19, an assessment was conducted by examining the association between the clinical and socio-demographic characteristics of consultants and the perceived facilitators and barriers influencing their future intent. Methods: Practicing oral and maxillofacial consultants were recruited through purposive and snowball sampling methods. Data were collected through surveys and key informant interviews. Chi-square tests were used to determine whether consultants’ clinical and socio-demographic characteristics and perceptions were associated with a willingness to use telehealth in the future. Coded interview transcripts were analyzed thematically to identify the main themes influencing their willingness. Results: Among the 42 respondents, 82% expressed a willingness to continue using telehealth services with the majority having at least 2 to 3 years (p = 0.028) of experience utilizing these services. The four main themes impacting consultants willingness include the accessibility of oral and maxillofacial healthcare, challenges addressing patient needs, the uncertainty of diagnostic accuracy and effectiveness as a post-operation observation tool. Conclusion: Most oral and maxillofacial consultants favored the routine use of telehealth services beyond COVID-19. Concern for patients’ needs was a key determinant of their continued use. Co-designing strategies to eliminate barriers and unmet needs for consultants and patients may improve oral and maxillofacial telehealth uptake.
Training and Resources Related to the Administration of Sedation by Nurses During Digestive Endoscopy: A Cross-Sectional Study
Authors: Hidalgo-Cabanillas Miriam , Laredo-Aguilera José Alberto , López-Fernández-Roldán Ángel , Molina-Madueño Rosa María , Rodriguez-Muñoz Pedro Manuel , Navarrete-Tejero Carlos , López-González Ángel , Rabanales-Sotos Joseba , Carmona-Torres Juan Manuel
Published: October 2024

Background: The healthcare professional who performs sedation for digestive endoscopy procedures is usually the nurse. Therefore, knowledge and training on the part of the nurse is an important factor for the correct sedation of the patient and may affect, among other factors, the quality of health care and the recovery and well-being of the patient. Objective: To determine the training opportunities and resources available to the specialists involved in digestive endoscopy services in hospitals in Spain in which sedation is performed by the nursing staff. Methods: This was a descriptive cross-sectional study performed in the Digestive Endoscopy Service at Toledo University Hospital and nearby hospitals in central Spain. The sample consisted of 75 nurses who administer sedation in digestive endoscopic procedures. Results: Regarding the training of nurses, the vast majority were generalist nurses, and only a small percentage obtained specialized training through ongoing training. Most had been working in the service for more than two years, and very few had previous experience in sedation, although the vast majority currently applied sedation. Life support training was also critical. There were significant differences in the availability of resources between different hospitals. Conclusions: The training of nurses who perform sedation in digestive endoscopy services could be improved since there is a high proportion of personnel without specific training in sedation before starting to work in the service. It is crucial to implement targeted and ongoing training programs to improve competencies in this area, as they are essential to ensure the safety and effectiveness of the procedure. Given the variability in resources and personnel training that exists between different hospitals, it seems important to establish standards at the institutional level.
A Single-Center Analysis of Patient Characteristics and Overall Survival in Patients with Resectable Gallbladder Cancer
Authors: Öztürk N. Begüm , Dadamyan Artem , Jamil Laith H.
Published: October 2024

Introduction: Gallbladder cancer (GBC) is a rare and aggressive hepatobiliary malignancy with poor prognosis. The symptoms of GBC are insidious and non-specific in its early stages, and most patients are diagnosed at advanced or late stages. Surgical resection is the only potentially curative treatment for GBC for select patients. There is a lack of robust data for patients with GBC, leading to heterogenous practices in management strategies and outcomes. In this study, we aimed to identify patient characteristics and cumulative overall survival (OS) in patients with GBC who underwent surgical resection with curative intent. Methods: All adult patients (age ≥18 years) with localized or locoregionally advanced GBC who underwent definitive surgery with curative intent at our tertiary institution between 1/2013 and 12/2023 were retrospectively identified. Clinical, laboratory, radiology, histopathology, treatment, and survival data were collected from electronic medical records. Postoperative data included the use of adjuvant chemotherapy or radiotherapy, and patient survival mortality at a cut-off date of 1 February, 2024, calculated from the date of curative surgery. Continuous variables are reported as median and quartile 1 (Q1) and quartile 3 (Q3), while categorical variables are reported as counts and percentages. Results: A total of 94 patients with GBC were included in the study. Median age was 71 (62–77) years and 58 (61.7%) patients were female. Median tumor size was 3.3 (1.9–5.0) cm. Perineural invasion was seen in 48.9% and vascular invasion in 38.3% of patients. A positive surgical margin was present in 50% of the patients, and incidental GBC (IGBC) was seen in 48.9% of patients. Tumor grade was well differentiated in 7.6%, moderately differentiated in 53.3%, and poorly differentiated in 39.1% of the patients. Patients with stage T1a (2.1%) and T1b (11.7%) tumors comprised the minority, and the majority of the tumors were stage T2 (55.3%), followed by T3 (31.9%). A total of 60.6% of patients with GBC underwent adjuvant chemotherapy, and 17% underwent adjuvant radiotherapy after surgical resection. Overall, 62 (66.0%) patients died, and the median OS was 1.88 years. The 1-year OS was 68.7%, 3-year OS was 37.4%, and 5-year OS was 32.2%. A higher absolute median OS was seen in patients who had adjuvant chemotherapy (2.1 years) compared to no chemotherapy (1.9 years); however, this finding was not statistically significant (p = 0.36). The median survival was 2.3 years in IGBC compared to 1.6 years in non-IGBC (p = 0.63). Conclusions: GBC is an aggressive hepatobiliary malignancy that is often diagnosed at advanced stages. Our study showed high rates of local and systemic involvement and high mortality, and the need for prospective and randomized studies on adjuvant therapies to assess their survival benefit. Real-world patient data remain important to identify patients at risk of worse outcomes and to stratify risks prior to surgery.
Mapping Obesity Trends in Saudi Arabia: A Four-Year Description Study
Authors: Althumiri Nora A. , Bindhim Nasser F. , Al-Rayes Saja A. , Alumran Arwa
Published: October 2024

Objective: Our study aims to map the trends in obesity prevalence over the past four years and to describe the health, behavior, and psychological factors of people living with obesity in Saudi. Method: This is a secondary data analysis using the Sharik Health Indicators Surveillance System (SHISS) from 2020 to 2023. The SHISS dataset comprises cross-sectional telephone interviews carried out quarterly across all administrative regions of Saudi Arabia. Recruitment of participants was restricted to Saudi resident adults only. Results: The study analyzed data from 92,137 participants, with a balanced region and gender distribution. The average age of participants was 36.83 ± 13.68 years. The prevalence of obesity showed minor fluctuations over four years, with the highest at 22.2% in 2020 and lowest at 21.4% in 2023. This study showed that a slight decline in daily smoking rates was observed from 2020 to 2023 across all categories. Participants living with obesity reported a higher consumption of fruits and vegetables compared to their not with obesity counterparts. In addition, participants living with obesity engaged less frequently in physical activities compared to those without obesity. Moreover, people living with obesity have higher incidence rates of depression and anxiety, as well as various of chronic diseases. Conclusions: This study highlights the complex factors affecting obesity prevalence in Saudi Arabia. Despite progress, ongoing health promotion and disease prevention are crucial to address the persistent challenges driven by behavioral and socio-economic factors. Continued surveillance and longitudinal studies are essential to track trends in obesity, smoking, and physical activity, ensuring that health initiatives align with population needs.
Facilitating Family Carer Dementia Education: We All Need to Learn
Authors: Jack-Waugh Anna , Holland Susan , Macrae Rhoda , Mimnaugh Jane , Tolson Debbie
Published: October 2024

Background/Objectives: The importance of family carer dementia education is highlighted in research, practice guidance, and policy. Less attention is paid to how facilitators learn and prepare for their role. This research aimed to explore and describe facilitator learning experiences within a bespoke Scottish Carers’ Academy designed around a theory-guided approach called Care Empathia. A healthcare and university partnership ensured integration with services and the fusion of dementia higher education know-how with clinical practice expertise. Methods: Nineteen facilitator questionnaires were completed from two Carer Academy hubs; thirteen participated in online focus groups. Results: The questionnaire findings highlighted the learning gained from being a facilitator, observing expert facilitators in action, and listening to the testimonies of family carers. The framework analysis of the focus group data identified six themes, including safe learning approaches, the art of facilitation, emotional work, team learning, and leadership. These findings highlight the importance of facilitator preparation and the advantages of co-delivery models that combine clinical and practice education expertise. Conclusion: Facilitators need to understand how to walk the talk of theory-guided educational models, be open to reciprocity in learning, and be prepared for the emotional work of delivering trauma-informed practical dementia care education to family carers.
Morphology and Allometry of Juvenile Açaí Palms Under Cultivation Conditions in Central Amazonia
Authors: Delgado Jhon Paul Mathews , da Cunha Raimundo Nonato Vieira , de Morais Ronaldo Ribeiro , Lopes Maria Teresa Gomes , Ramos Santiago Linorio Ferreyra , Rodrigues Maria do Rosário Lobato , de Medeiros Nathalia Maíra Cabral , Meneses Carlos Henrique Salvino Gadelha , Barcelos Edson , Lopes Ricardo
Published: October 2024

Two Amazonian species of açaí palm trees (Euterpe oleracea and Euterpe precatoria) are exploited in the commercial production of açaí pulp or juice. While E. oleracea benefits from developed cultivation technologies, E. precatoria lacks such advancements. Studies on the morphology and development of açaí palms under cultivation conditions can contribute to increasing the productivity of the species. The aim of this study was to carry out morphological characterization, assess growth and development in the juvenile phase of the plants, and obtain allometric models for E. precatoria and E. oleracea. Evaluations were conducted between 44 and 48 months post-planting. Allometric equations were formulated to accurately estimate leaf area. The results showed that E. oleracea begins reproduction earlier and exhibits greater growth in stem dimensions and leaf areas compared to E. precatoria, indicating that E. precatoria can be cultivated at higher planting densities. Allometric models, based on leaf length and width, effectively predicted individual leaf areas for both species, demonstrating their utility in optimizing cultivation strategies.
MODIS Evapotranspiration Forecasting Using ARIMA and ANN Approach at a Water-Stressed Irrigation Scheme in South Africa
Authors: Phesa Mbulelo , Mbatha Nkanyiso , Ikudayisi Akinola
Published: October 2024

The forecasting of evapotranspiration (ET) in some water-stressed regions remains a major challenge due to the lack of reliable and sufficient historical datasets. For efficient water balance, ET remains the major component and its proper forecasting and quantifying is of the utmost importance. This study utilises the 18-year (2001 to 2018) MODIS ET obtained from a drought-affected irrigation scheme in the Eastern Cape Province of South Africa. This study conducts a teleconnection evaluation between the satellite-derived evapotranspiration (ET) time series and other related remotely sensed parameters such as the Normalised Difference Vegetation Index (NDVI), Normalised Difference Water Index (NDWI), Normalised Difference Drought Index (NDDI), and precipitation (P). This comparative analysis was performed by adopting the Mann–Kendall (MK) test, Sequential Mann–Kendall (SQ-MK) test, and Multiple Linear Regression methods. Additionally, the ET detailed time-series analysis with the Keiskamma River streamflow (SF) and monthly volumes of the Sandile Dam, which are water supply sources close to the study area, was performed using the Wavelet Analysis, Breaks for Additive Seasonal and Trend (BFAST), Theil–Sen statistic, and Correlation statistics. The MODIS-obtained ET was then forecasted using the Autoregressive Integrated Moving Average (ARIMA) and Artificial Neural Networks (ANNs) for a period of 5 years and four modelling performance evaluations such as the Root Mean Square Error (RMSE), Mean Absolute Percentage Error (MAPE), Mean Absolute Error (MAE), and the Pearson Correlation Coefficient (R) were used to evaluate the model performances. The results of this study proved that ET could be forecasted using these two time-series modeling tools; however, the ARIMA modelling technique achieved lesser values according to the four statistical modelling techniques employed with the RMSE for the ARIMA = 37.58, over the ANN = 44.18; the MAE for the ARIMA = 32.37, over the ANN = 35.88; the MAPE for the ARIMA = 17.26, over the ANN = 24.26; and for the R ARIMA = 0.94 with the ANN = 0.86. These results are interesting as they give hope to water managers at the irrigation scheme and equally serve as a tool to effectively manage the irrigation scheme.
A Scoping Review of Acute Sedentary Behaviour Studies of People with Spinal Cord Injury
Authors: Adams Nathan T. , Tong Bobo , Buren Robert , Ponzano Matteo , Jun Jane , Martin Ginis Kathleen A.
Published: October 2024

People with a spinal cord injury (SCI) report less physical activity than other populations and may engage in more sedentary behaviour (SB), especially sitting time. SB negatively impacts physiological and psychosocial outcomes in the general population, yet minimal research has explored the effects in people with SCI. The goal of this scoping review was to catalogue and describe the effects of acute SB among people with SCI. We searched four databases before February 2024 for studies in which people with any SCI sat, laid, or reclined for more than one hour in a day, and any physiological, psychological, or behavioural (i.e., SB time) outcome was measured. In total, 2021 abstracts were screened, and eight studies were included (n = 172 participants). The studies were characterized by varied definitions, manipulations, and measures of SB. Most measured outcomes were physiological (e.g., metabolic, blood pressure), followed by behavioural (e.g., SB time) and psychological (e.g., well-being, affect). When SB was interrupted, only postprandial glucose and affect improved. Based on two studies, participants engaged in 1.6 to 12.2 h of SB per day. Average uninterrupted wheelchair sitting bouts lasted 2.3 h. Based on the very limited body of research, it is impossible to draw any conclusions regarding the nature, extent, or impact of SB in people with SCI. There is much work to carry out to define SB, test its effects, and determine if and how people with SCI should reduce and interrupt SB.
Musculoskeletal, Pulmonary, and Cardiovascular COVID-19 Sequelae in the Context of Firefighter Occupational Health: A Narrative Review
Authors: Graham Elliot L. , D’Isabel Susanne , Lofrano-Porto Adriana , Smith Denise L.
Published: October 2024

For most individuals infected with SARS-CoV-2, the acute illness resolves completely. However, for millions of people, symptoms or sequelae from COVID-19 recur or persist for months to years after infection. Post-COVID-19 sequelae are wide-ranging, often affecting the musculoskeletal, pulmonary, and cardiovascular systems. All who experience post-COVID-19 sequelae face significant challenges navigating home and work life. Occupations such as firefighting, however, are of particular concern given the strenuous nature of a job that relies on a healthy musculoskeletal, pulmonary, and cardiovascular system. Research has documented significant musculoskeletal impairment (including muscle weakness, pain, and fatigue), respiratory dysfunction (including reduced lung function, interstitial disease, and diffusion abnormalities), cardiovascular conditions (including cardiac events, ischemic disease, dysrhythmias, and infectious diseases), and diminished cardiorespiratory fitness that continues for months to years in some individuals. These persistent post-COVID-19 conditions may affect a firefighter’s ability to return to work, function at full capacity while at work, and potentially compromise firefighter health and public safety. This review, therefore, explores musculoskeletal, pulmonary, and cardiovascular sequelae post-COVID-19 and the impact of these sequelae on firefighter health and occupational readiness.
Strategies for Confronting the COVID-19 Pandemic in the State of Piauí—Brazil: Contributions to Nursing
Authors: Oliveira Thais Alexandre de , Mori Flor Marlene Luna Victoria , Oviedo Aracely Diaz , Araújo Telma Maria Evangelista de , Freitas Daniela Reis Joaquim de , Valle Andréia Rodrigues Moura da Costa , Batista Odinéa Maria Amorim , Madeira Maria Zelia de Araujo , Pérez Neris Violeta González , Moura Maria Eliete Batista
Published: October 2024

The COVID-19 pandemic has led to the adoption of rapid, complex, and changeable measures. These measures allowed effective care planning and implementation of emergency management strategies to meet the needs of the population. Objective: To analyze the influence of the strategies to cope with the COVID-19 pandemic, implemented by the Public Health Network of the State of Piauí, Brazil, as contributions to nursing, on the outcome of cases and deaths. Method: This is a descriptive and documentary study with a qualitative approach, carried out in the state of Piauí—Brazil, whose data were processed at IRAMUTEC and analyzed by the Descending Hierarchical Classification (DHC). Results: Ninety-two normative acts were instituted as coping strategies, distributed in three classes: technical-operational protocols for preventing and combating COVID-19 in Piauí; Piauí strategic bases for social distancing against COVID-19; and management of services and economic activities in Piauí in the fight against COVID-19. Conclusions: The actions determined by and implemented in the normative acts were conducted according to the behavior of the epidemiological curve regarding the number of cases and deaths. The normative acts, which defined the technical-operational protocols for the prevention and control of COVID-19, were directly related to social distancing strategies and the use of protective equipment in the quality of life of the population.
People at Risk of, or with Cardiovascular Diseases’ Perspectives and Perceptions of Physiotherapist-Led Health Promotion in Cameroon: A Mixed-Methods Study
Authors: Ngeh Etienne Ngeh , McLean Sionnadh , Kuaban Christopher , Young Rachel , Strafford Ben W. , Lidster Joanne
Published: October 2024

Cardiovascular diseases (CVDs) and their risk factors are a major cause of illness and death worldwide, especially in low- and middle-income countries like Cameroon. Physiotherapist-led health promotion (PLHP) has proven effective in improving health and reducing CVD risks. Understanding patient perspectives is crucial for designing effective, context-specific PLHP interventions. This study explored patients’ views, experiences, perceived usefulness, acceptability, and preferred methods of PLHP, through a sequential explanatory mixed-methods approach. The quantitative data highlights a significant burden of CVD conditions and risk factors among patients seen in physiotherapy services. Qualitatively, three themes were identified and included: (1) perspectives and experiences of people at risk or with CVDs (pwCVDs) on PLHP; (2) perceived usefulness and acceptability of PLHP; (3) preferred delivery methods of PLHP. Participants reported positive feedback on PLHP and physiotherapy services. Barriers to effective PLHP included high workloads for physiotherapists, limited service access in rural areas, and prohibitive costs. Despite these challenges, participants expressed strong confidence in physiotherapists’ competence, though they also called for improved regulation and ongoing professional development. PLHP components, especially physical treatment and dietary advice, were deemed highly useful and acceptable. Patients suggested various delivery methods, including peer support groups, home visits, and mass media interventions. This study highlights the need to improve the scope of practice, competence of physiotherapists, and accessibility of physiotherapy services in Cameroon for pwCVDs. It is necessary to adopt multidisciplinary approaches to achieve better outcomes for risk factors like diabetes and hypertension in context.
Cultural Insiders and Graphic Stories to Promote Research Readiness Among the South Asian Community: A Focus on Purpose, Protection, and Participation
Authors: Patel Yatra N. , Patel Riya J. , Bates Lauren , Gertz Susan , Hershberger Susan , Butsch Kovacic Melinda
Published: October 2024

South Asians living in the United States are frequently underrepresented in health research. Their lack of participation limits the generalizability of research to them and keeps them from receiving the high-quality care and innovation that some studies may offer. “Research Ready” is a five-panel, community co-created graphic-style story that encourages discussion around the purpose of research, safety/protection while participating, and why diverse participation—including South Asians—improves study results and leads to more effective interventions/treatments. This study leveraged trained young adult “cultural insiders” to invite attendees of a Midwestern South Asian Cultural Festival to read the story aloud together as the characters in English or Hindi and used a decision guide to invite discussion. Post-discussion surveys (N = 104) were analyzed using descriptive statistics. Participants spanned from 10 to 79 years, with 42% < 18 years and more females (61%). Only 18.3% indicated having prior research participation. Adults 40+ years (60%) requested the story/discussion in Hindi, compared to 2.3% of adolescents and 6.7% of younger adults. After the discussion, participants indicated their willingness to consider participation, with most being open to participating in surveys/interviews (95.2%); only 52.9% would consider studies requiring the taking of medicines. Adolescents, females, and adults with higher education were more willing to participate in medication studies. Nearly all (97.1%) said they would feel safe participating in research, and 88.5% shared that the discussion would help them better decide about future participation. In conclusion, “Research Ready” discussions shared by cultural insiders effectively encourage South Asians to consider future research participation.
Towards ‘Formalising’ WhatsApp Teledermatology Practice in KZ-N District Hospitals: Key Informant Interviews
Authors: Morris Christopher , Scott Richard E. , Mars Maurice
Published: October 2024

Introduction: District hospitals in KwaZulu-Natal Province, South Africa, do not have onsite specialist dermatology services. Doctors at these hospitals use WhatsApp instant messaging to informally seek advice from dermatologists and colleagues before possible referral. They have expressed the need to formalise WhatsApp teledermatology. Aim: To determine the views and perspectives of clinicians on the feasibility and practicality of formalising the current WhatsApp-based teledermatology activities within the KwaZulu-Natal Department of Health Dermatology Service. Methods: Key informant interviews with 12 purposively selected doctors at district hospitals and all 14 dermatologists in the KwaZulu-Natal dermatology service. Their views and perspectives on formalising the current informal use of WhatsApp for teledermatology were recorded, transcribed, and thematically analysed. Results: Five primary themes (communication, usability, utility, process, and poor understanding of legal, regulatory, and ethical issues) and 22 sub-themes were identified. Clinicians wanted WhatsApp teledermatology to continue, be formalised, and be incorporated within the KwaZulu-Natal Department of Health, facilitated by the provision of practical guidelines addressing legal, regulatory, and ethical issues. Conclusions: These findings will be used to develop a policy brief, providing recommendations and proposed guidelines for formalising the teledermatology service. The findings and methods will be relevant to similar circumstances in other countries.
Spatiotemporal Information, Near-Field Perception, and Service for Tourists by Distributed Camera and BeiDou Positioning System in Mountainous Scenic Areas
Authors: Shi Kuntao , Zhu Changming , Li Junli , Zhang Xin , Yang Fan , Zhang Kun , Shen Qian
Published: October 2024

The collaborative use of camera near-field sensors for monitoring the number and status of tourists is a crucial aspect of smart scenic spot management. This paper proposes a near-field perception technical system that achieves dynamic and accurate detection of tourist targets in mountainous scenic areas, addressing the challenges of real-time passive perception and safety management of tourists. The technical framework involves the following steps: Firstly, real-time video stream signals are collected from multiple cameras to create a distributed perception network. Then, the YOLOX network model is enhanced with the CBAM module and ASFF method to improve the dynamic recognition of preliminary tourist targets in complex scenes. Additionally, the BYTE target dynamic tracking algorithm is employed to address the issue of target occlusion in mountainous scenic areas, thereby enhancing the accuracy of model detection. Finally, the video target monocular spatial positioning algorithm is utilized to determine the actual geographic location of tourists based on the image coordinates. The algorithm was deployed in the Tianmeng Scenic Area of Yimeng Mountain in Shandong Province, and the results demonstrate that this technical system effectively assists in accurately perceiving and spatially positioning tourists in mountainous scenic spots. The system demonstrates an overall accuracy in tourist perception of over 90%, with spatial positioning errors less than 1.0 m and a root mean square error (RMSE) of less than 1.14. This provides auxiliary technical support and effective data support for passive real-time dynamic precise perception and safety management of regional tourist targets in mountainous scenic areas with no/weak satellite navigation signals.