bluuebunny/crossref_metadata_2025 huggingface dataset:
Analisis Potensi Pajak Restoran dan Kontribusinya pada Pendapatan Asli Daerah Kabupaten Badung
Authors: Made Wulandewi Desak , Supadmi Ni Luh
Published: July 2020

The purpose of this study is to determine the potential and contribution of restaurant tax in Kuta district as a source of PAD in Badung Regency. This research was conducted in 73 restaurants, 11 restaurants and 4 bars in Kuta District with the method of determining the probability sampling method, namely simple random sampling. Data collection is done by non-participant observation and questionnaires. The analysis technique used is quantitative descriptive. Based on the results of the study, it is known that the potential for restaurant tax in Kuta District is in a very stable (optimistic) condition of 77,787,570,060 rupiahs. In a stable (moderate) economic condition the target was set at 29,429,630,673 rupiahs and in an economic condition that was less stable (pessimistic) at 25,929,190,020 rupiahs. The contribution of restaurant taxes in Kuta district from the number of samples that researchers used in this study amounted to 0.55 percent of the revenue of Badung Regency PAD.

Keywords: Potential; Contribution; Local Original Revenue.
Pengaruh Asset Growth, Leverage, dan Dividend Payout Ratio pada Volatilitas Harga Saham
Authors: Artikanaya I Kadek Rama , Gayatri Gayatri
Published: July 2020

This study aims to obtain empirical evidence about the effect of asset growth, leverage, and dividend payout ratio on stock price volatility. This research was conducted on companies listed in the LQ 45 index on the Indonesia Stock Exchange in 2014 - 2018. The number of samples used was 13 companies using the nonprobability sampling method with a purposive sampling technique, so the number of samples for 5 years became 65 samples. The data analysis technique used is multiple linear regression analysis. Based on the results of the analysis found that asset growth has a negative effect on stock price volatility. Leverage has a positive effect on stock price volatility. Dividend payout ratio has a negative effect on stock price volatility.

Keywords: Asset Growth; Leverage; Dividend; Volatility.
Determinan Keberhasilan Penerapan Sistem Akuntansi Instansi Berbasis Akrual Dalam Penyusunan Laporan Keuangan Pemerintah
Authors: Irfani Muhajir , Pituringsih Endar , Hamdani Husnan Lalu
Published: July 2020

The manifestation of the application of government accounting standards is the WTP opinion from BPK. This study aims to examine the effect of financial staff education, accounting training, the use of the SAIBA application, and organizational commitment to the successful application of an accrual-based accounting system. This research was conducted at the Land Office work unit within the scope of the NTB Province BPN Regional Office. Respondents numbered 63 people. Data analysis techniques used multiple linear regression analysis. The results showed that organizational commitment had a positive effect, the use of the SAIBA application had a negative effect, but financial staff education and accounting training had no effect on the successful application of the accrual-based agency accounting system.

Keywords: Financial Staff Education; Accounting Training; SAIBA; Organizational Commitment; Accrual Based Institution Accounting System.
Analisis Penetapan Harga Pokok Produksi pada Perusahaan Manufaktur di Provinsi Daerah Istimewa Yogyakarta
Authors: Nasution Dito Aditia Darma , Muda Iskandar
Published: July 2020

This study aims to analyze and describe how the determination of the cost of production in manufacturing companies in the Special Region of Yogyakarta Province. The method used in this study is a qualitative approach using instruments in the form of questionnaires and interviews as supporters addressed to the owners of several manufacturing companies in the Special Region of Yogyakarta Province. The research sample of 52 manufacturing companies consisting of 33 medium scale companies and 19 large scale companies. The results showed that the company has more than one goal in setting the cost of production. The most important finding is that the main factor affecting the cost of production is cost. It was also found that all of the samples tested believed that changes in the cost of production would not be effective in increasing sales volume.

Keywords: Implementation of Pricing; Market Based Pricing; Cost Based Pricing; Product Cost.
Peranan BUMDesa dalam Meningkatkan Kemandirian Ekonomi Desa
Authors: Gayatri Gayatri , Widhiyani Ni Luh Sari
Published: July 2020

BUMDesa is an elaboration of the vision of national development that is the realization of a sovereign, independent, and personality based on mutual cooperation. In the Province of Bali only 65% ??of the villages have BUMDesa. BUMDesa is expected to be a driving force for the village economy. The purpose of this study is to determine the role of BUMDesa in increasing the economic independence of the village. The population in this study are all village-owned enterprises in the Province of Bali. The location of the study was conducted in Gianyar Regency. The sample collection technique uses purposive sampling. Data collection techniques are carried out through questionnaires. Data analysis techniques using multiple linear regression. This research proves that partially, economic independence has a positive role in BUMDesa in Gianyar Regency. Intellectual independence has a positive role in BUMDesa in Gianyar Regency. And organizational independence has a positive role in BUMDesa in Gianyar Regency. Together economic independence, intellectual independence and organizational independence have a positive role in BUMDesa in Gianyar Regency.

Keywords: BUMDesa; Economic Independence.
MODEL PENGELOLAAN LINGKUNGAN DI KAWASAN PARIWISATA NUSA PENIDA, BALI
Authors: Sudipa Nyoman , Sudiana Mahendra Made , Sandi Adnyana Wayan , Pujaastawa Ida Bagus
Published: July 2020

As a regional income barn, the Nusa Penida Tourism Area needs to be managed comprehensively by involving all available resources, by encouraging new thinking about managing tourism that synergizes with environmental sustainability in the sustainable environment of the Nusa Penida Tourism Area. Tourism can increase economic growth but create a burden on the environment, so that Nusa Penida tourism becomes environmentally friendly tourism to support the development of green tourism. Progress in tourism impacts the environment, causes social and cultural changes in society and impacts the carrying capacity of land and water from the massive tourism development in Nusa Penida. For this reason, it is necessary to formulate a model of environmental management that is relevant and has been developed.This study uses a systems approach with the Interpretative Structural Modeling (ISM) method to formulate an environmental management model in the Nusa Penida Tourism Area. This method can be used to help a group, in identifying contextual relationships between sub elements of each element that forms a system based on ideas / structures or determinants in a complex problem (Saxena, 1992).The environmental management model in the Nusa Penida was formed based on government initiatives by involving all stakeholders as representatives of the Nusa Penida community and involving other elements such as non-government organizations and universities. In the management of the environment, institutional arrangements that specifically handle the environment and tourism of Nusa Penida must be formed with the government as the initiator and formed in a participatory manner. The recommended model of environmental management needs to be applied carefully and continued with the formation of institutions by involving the affected community sectors in Nusa Penida's environmental management and tourism.Keywords: tourism, model, management, environment, Nusa Penida
PRELEMINARY ANALYSIS OF CAUSE-EFFECT ON FOREST-PEATLAND FIRES PRIOR TO 2020 IN CENTRAL KALIMANTAN
Authors: Yulianti Nina , Kusin Kitso , Murni Elvi , Barbara Betrixia , Naito Daisuke , Kozan Osamu , Jagau Yusurum , Kulu Ici Piter , Adji Fengky Florante , Susetyo Kurniawan Eko
Published: July 2020

Central Kalimantan covers an area of 157,983 km2 with more than 2,000 km2 of tropical peatlands, which is one of the buffer regions of Indonesia's new capital government city. However, the sad story is the conversion of about one million hectares from peat swamp forests (PSF) to rice fields occurred in the mid-1990s, so called the Mega Rice Project (MRP). Since then, forest and peatland fires become an annual event due to high level of degradation under the climate change symptoms such the frequent of the El Niño event. In very strong El Niño of 2015, Indonesia has returned to the world spotlight in relation to the fires and the haze crisis. The most fire prone area was recorded in the iconic Tumbang Nusa, Pulang Pisau Regency and its adjecent areas. However, the thick haze had covered almost the entire province. There are the dis-adventages impact during more than two months. Therefore, this study was to investigate what are the causes and the impacts of this disaster at the site level. This research location was focuses on three regencies and one city namely Pulang Pisau, Kapuas, Katingan and Palangka City. The method was a Focus Group Discussion (FGD) with key figures representing eight clusters of village communities. This method is also supported by statistical, hotspots and spatial data for additional analysis. The result are only two villages with very high average of hotspot and eight with high average of hotspots in Pulang Pisau and Kapuas Regency. Further, the FGDs in seven villages showed that there were three main clusters that caused forest-land fires, namely natural factors, human factors and village policy / regulation factors. The villages study that were affected by the fire in 2015 showed there were three main impacts namely on people, environment and capital. This result is a foundation of cause-effect factor for further Root Cause Analysis to find out the options for fire prevention and management in climate change mitigation efforts.

Keywords: Climate Change; El-Niño; Fires; Focus Group Discussion; Peatland
Psikososial dan Beban Kerja Perawat – Sebuah Penelitian di Salah Satu RS Militer di Indonesia
Authors: Iridiastadi Hardianto , Septiawati Vera , Yuliani Euis Nina Saparina , Hernadewita Hernadewita
Published: July 2020

Penelitian ini bertujuan untuk mengetahui tingkat beban kerja mental dan faktor psikososial dari para perawat tingkat pelaksana di ruang rawat inap rumah sakit militer. Data diambil dari penyebaran kuesioner kepada 41 perawat tingkat pelaksana yang bertugas di ruang rawat inap. Pengukuran beban kerja mental dilakukan dengan menggunakan kuesioner National Aeronautics and Space Administration – Task-Load Index (Nasa–TLX). Pengukuran faktor psikososial dilakukan dengan menggunakan kuesioner The Copenhagen Psychosocial Questionnaire (COPSOQ II). Hasil penelitian menunjukkan bahwa nilai rerata keseluruhan beban kerja mental berada pada kategori tinggi. Nilai faktor psikososial lingkungan kerja menunjukkan hasil yang baik pada mayoritas skala penilaian. Akan tetapi, pihak rumah sakit perlu memperhatikan beberapa faktor seperti tuntutan emosi, persepsi kesehatan, kelelahan dan stres serta aspek tempo pekerjaan. Hasil penelitian ini juga menunjukkan adanya hubungan positif yang kuat dan signifikan antara dimensi kepercayaan manajemen dengan kinerja dengan r=0,545 (p=0,000). Dengan demikian, disarankan agar pihak manajemen rumah sakit tidak hanya melakukan penilaian terhadap kinerja para perawat tetapi dapat juga melakukan penilaian beban kerja mental dan faktor psikososial secara berkala agar tercipta lingkungan kerja yang kondusif
Hubungan Masa Kerja Dan Lama Kerja Dengan Nyeri Leher Pada Pembatik Di Sentra Batik Giriloyo
Authors: Yani Fitri , Anniza Meiza , Priyanka Krisnawan
Published: July 2020

Pembatik bekerja dengan sikap kerja duduk statis dan tidak ergonomis dalam waktu 8 jam. Apabila sikap kerja duduk statis dan tidak ergonomis berlangsung dalam jangka panjang, maka akan menimbulkan keluhan muskuloskeletal terutama pada bagian leher. Penelitian ini bertujuan untuk mengetahui hubungan masa dan lama kerja dengan nyeri leher pada pembatik di sentra batik Giriloyo. Metode penelitian adalah observasional dengan pendekatan cross sectional dan teknik pengumpulan data menggunakan kuesioner yang valid dan reliabel. Teknik pengambilan sampel purposive sampling. Sampel penelitian adalah pembatik di sentra batik Giriloyo yang berjumlah 89 pembatik. Hasil uji statistik korelasi Rank Spearman diperoleh adanya hubungan antara masa kerja dengan nyeri leher dengan nilai r=0,313 (p<0,05). Hubungan lama kerja dengan nyeri leher diperoleh nilai r=0,299 (p<0,005). Pengaruh lama kerja (exp. B=1,906) lebih dominan dibandingkan masa kerja terhadap nyeri leher. Disimpulkan ada hubungan masa kerja dan lama kerja dengan nyeri leher pada pembatik di sentra batik Giriloyo. Pengaruh lama kerja lebih dominan dibandingkan masa kerja terhadap terjadinya nyeri leher pada pembatik di sentra batik Giriloyo.
HOME BASED EXERCISE TRAINING (HBET) DAPAT MENINGKATKAN KAPASITAS FUNGSIONAL PASIEN GAGAL JANTUNG
Authors: Yuni Lestari Ni Kadek
Published: July 2020

Pendahuluan: Latihan fisik untuk meningkatkan kapasitas fungsional pada penderita gagal jantung masih belum mendapatkan perhatian khusus dari petugas kesehatan. Kapasitas fungsional yang menurun berdampak pada penurunan kemampuan pasien dalam melakukan aktivitas sehari-hari. Tujuan penelitian : menganalisis peningkatan kapasitas fungsional setelah diberikan home based exercise training pada pasien gagal jantung. Metode: desain penelitian pra-eksperimen yaitu one group pretest-posttest design. Teknik sampling yang digunakan adalah purposive sampling, didapatkan 10 responden. Peneliti menggunakan teknik 6MWT untuk mengumpulkan data kapasitas fungsional. Hasil : analisa data dilakukan dengan menggunakan uji paired t test. Hasil analisa dapat diperoleh nilai p = 0,001 (?=0,05). Berdasarkan hasil penelitian menunjukkan kapasitas fungsional sebelum diberikan latihan adalah 245m dan setelah perlakuan sebesar 255 m. Diskusi: latihan fisik secara bertahap menyebabkan peningkatan daya pompa ventrikel sehingga terjadi peningkatan kapasitas fungsional. HBET dapat digunakan sebagai terapi modalitas keperawatan untuk meningkatkan kapasitas fungsional pasien gagal jantung setelah perawatan di rumah sakit.
POPS case: A 30-year-old Filipino woman with fevers, lymphadenopathy, painful scalp lesions, and a neck mass
Authors: Daley Aparna S. , Naro Gillian R. , Craig Timothy J. , Hussein Rezhan H.A. , Banjade Rashmi , Jacobs Jennifer B. , Ross Ian R.
Published: July 2020

We described a case of a 30-year-old Filipino woman who presented with fevers, night sweats, left hip pain, painful scalp lesions, and a neck mass. Symptoms began 6 months earlier, with nasal drainage, fever, cough, and occasional hemoptysis, which did not resolve with outpatient antibiotics.
A further workup revealed lymphadenopathy and several lytic bone lesions. Her hospital course was later further complicated by the development of a tracheoesophageal fistula secondary to an esophageal mass and, then later, aseptic meningitis. Extensive diagnostic workup and immunologic tests
were performed and finally led to the diagnosis. Here, we discussed the diagnostic workup and pathophysiology of the underlying condition. This case illustrated the importance of appropriate immunologic workup to make the diagnosis of a rare condition that proves to be clinically significant
and presents challenges in management.
Artistas, trabajadores y emprendedores: disyuntivas y desafíos de la profesionalización del cine chileno
Authors: Peirano María Paz
Published: July 2020

Este artículo analiza el proceso de profesionalización del cine chileno reciente. A partir de una etnografía multisituada de larga duración, se da cuenta de los procesos de subjetivación artística y profesional de los y las cineastas chilenos durante la última década y se reflexiona sobre las fisuras de dicho proceso en la experiencia de la “comunidad” de realizadores, agentes clave del campo cinematográfico. El artículo plantea que las prácticas de profesionalización en escuelas y festivales de cine han impactado en los modos de hacer y pensar el cine chileno, tensionando sus marcos de sentido tradicionales y arrastrando una relación conflictiva entre el deber ser y las expectativas del mundo artístico, por un lado, y aquellas del emprendimiento económico del mundo industrial, por el otro. De esta manera, se busca explorar las disyuntivas de la experiencia creativa de estos artistas-profesionales en el marco de las orientaciones neoliberales del Chile contemporáneo.
Teoría marxista del Estado y sus usos en la antropología
Authors: Calderón Matías
Published: July 2020

Con el objetivo de robustecer las bases teóricas de la reflexión y movilización política del presente, en este escrito, hacemos una revisión de algunos autores claves de la teoría marxista del Estado, de sus usos en la antropología en general y la latinoamericana en específico. Sostenemos que el análisis y recuperación criteriosa de teorías que puedan apoyar la reflexión crítica, la elaboración de propuestas y la práctica política, es un aporte que las ciencias sociales y la antropología debemos realizar en la actualidad.
Ciclo de conversaciones Antropologías del Sur: Milka Castro Lucic
Authors: Espinoza Claudio , Campos Luis , Contreras Paula
Published: July 2020

En esta tercera entrevista del ciclo de conversaciones Antropologías del Sur, cuyo fin es revisar y pensar formas no hegemónicas de la disciplina, se presenta la trayectoria académica e intelectual de Milka Castro Lucic (Iquique, 1949), quien, desde sus inicios en la antropología, recorre un camino amplio para convertirse en experta en materias relacionadas con el derecho propio de los pueblos indígenas, la antropología jurídica, los derechos de agua y el estudio con poblaciones del norte grande y chico de Chile. La entrevista nos muestra sus inicios en el campo de la antropología que acompañan la institucionalización formal de la disciplina en la Universidad de Chile. En su relato aparecen hitos de gran importancia para la antropología chilena, como fueron el impacto en la naciente disciplina del golpe de estado de 1973, los intentos por mantener activa la carrera y las características de una escuela que debió acomodarse a un contexto dictatorial. También a lo largo de su vida se puede apreciar su participación directa en los primeros procesos de organización del Colegio de Antropólogos de Chile, de la organización de los primeros congresos de la disciplina en el país y también de otras instancias organizativas en el Ámbito latinoamericano y mundial, como la Asociación Latinoamericana de Antropología (ALA) y la Red Latinoamericana de Antropología Jurídica (RELAJU). Sus investigaciones sobre el agua en el norte de Chile como su amplio trabajo en toda esa zona muestran a una destacada antropóloga chilena que ha conseguido trascender las fronteras nacionales contribuyendo tanto a la difusión como a la valorización de la antropología chilena en Latinoamérica y el mundo.
Discurso gramatical y contextualización: descripciones interlingüísticas de docentes de francés en México
Authors: Blin Béatrice , Olmedo Yúdico Becerril Rodrigo , Martínez de Badereaux Víctor
Published: July 2020

Interesados en las particularidades del discurso gramatical del docente de francés en México, el objetivo de este artículo es analizar, explicitar y categorizar un conjunto de rasgos característicos de las descripciones interlingüísticas enunciadas por un grupo de profesores referentes a los determinantes posesivos. Nuestra metodología se basó en una serie de entrevistas en grupo focal con 13 profesores de la Universidad Nacional Autónoma de México. El análisis de contenido de las transcripciones nos permitió observar marcas importantes de contextualización en las descripciones, que categorizamos en cinco posicionamientos: oposición, diferenciación, acercamiento, equivalencia cruzada y equivalencia total. Estos mecanismos son la evidencia de la movilización de recursos estratégicos por parte de los docentes, que contribuyen en la elaboración de una gramática de la comprensión.
Secuencia didáctica metadiscursiva para el desarrollo del ensayo argumentativo escrito en inglés de estudiantes de Licenciatura en Lenguas Extranjeras
Authors: Galindo Angelmiro , Moreno Serna Lina María
Published: July 2020

El artículo da cuenta de una investigación-acción centrada en la implementación de una secuencia didáctica metadiscursiva y su impacto en la construcción de la superestructura, macroestructura y microestructura del ensayo argumentativo escrito en inglés/L2, en 24 estudiantes en formación bilingüe universitaria de 4º semestre de una licenciatura colombiana en lenguas extranjeras (inglés y francés). Los instrumentos de recolección de datos fueron: (1) Prueba de producción del ensayo argumentativo escrito en inglés/L2, (2) Rúbrica de evaluación del ensayo argumentativo escrito en inglés/L2, (3) Diario del docente y (4) Portafolio del estudiante. Los hallazgos revelaron que, por un lado, el diagnóstico justificó la intervención didáctica metadiscursiva en la producción del ensayo argumentativo y, por el otro, dicha intervención mejoró los desempeños en la superestructura y en ciertas medidas de la macroestructura y la microestructura argumentativa. Se concluyó que el impacto respectivo depende del aspecto focalizado de la estructura del ensayo y que hubo regulación consciente del proceso de escritura.
Procesos de legitimación discursiva entre la medicina alópata y la medicina tradicional: el caso del tlahuica en el Estado de México
Authors: Nava Gómez Guadalupe Nancy , Alemán Martínez Rosa María
Published: July 2020

El artículo contiene un abordaje sobre los procesos de legitimación discursiva entre las prácticas de medicina tradicional y las prácticas alópatas desde la antropología lingüística. El objetivo central consiste en identificar la racionalidad entre estos dos modos de la experiencia humana: la objetiva-intelectiva y la subjetiva-afectiva. Los objetivos específicos son:1) la revaloración de la medicina tradicional a través de la reconstrucción del proceso de legitimación, 2) la recuperación del saber asociado con la medicina tradicional en México.
La metodología corresponde a un análisis semiótico desde la teoría de la producción de los signos y se hace una comparación entre la estructura y los sistemas de relaciones de ambos códigos lógicos y sociales. Como resultados de la investigación se destacan: la documentación sobre los procesos de legitimación de la medicina tradicional, se visibilizan grupos en proceso de recuperación de prácticas ancestrales y se propone la revitalización y el mantenimiento de lenguas indígenas en México.
El español de Colombia. Nueva propuesta de división dialectal
Authors: Ruiz Vásquez Néstor Fabián
Published: July 2020

El presente estudio ofrece una nueva división dialectal del español de Colombia, que ajusta las propuestas previas mediante la incorporación de datos lingüísticos y dialectológicos recientes, la elaboración de un nuevo modelo espacial de la estructuración dialectal basado en el concepto de escala, y la consideración de todo el territorio colombiano continental para la propuesta. El estudio identifica y caracteriza cinco nuevas variedades diatópicas previamente no consideradas en la discusión sobre el español colombiano, integra de modo coherente el español de Colombia en el marco del español americano, y señala algunas de las necesidades de la investigación dialectológica actual en el país.
Literature Review : Analisis Fishbone Diagram dalam Pelaksanaan Early Warning Alert And Respon System (EWARS) pada Deteksi KLB
Authors: Wanodya Kartika Sari
Published: July 2020

Meningkatnya kejadian luar biasa (KLB) menyebabkan suatu negara harus waspada serta siap akan wabah penyakit menular karena merupakan salah satu penyebab kesakitan, kematian dan dapat mengganggu produktivitas sehingga berdampak pada aspek seperti ekonomi dan sosial. Di Indonesia sendiri terdapat Early Warning Alert And Respon System atau EWARS yang diperlukan guna deteksi dini KLB. EWARS akan menampilkan alert ketika pencatatan suatu kasus melebihi ambang batas suatu wilayah. EWARS yang berjalan baik dapat dilihat dari ketepatan dan kelengkapan laporannya sehingga akan menghasilkan informasi data yang akurat dan berkualitas. Tujuan dari penelitian ialah menganalisis pelaksanaan Early Warning Alert And Respon System (EWARS) dalam deteksi dini KLB dengan fishbone diagram. Penelitian ini menggunakan metode literature review yang dianalis dengan fishbone diagram.Dilihat dari lima tools manajemen maka hasilnya yaitu: (1) man : adanya rangkap tugas dan jabatan pada petugas, pelatihan yang belum merata terutama petugas yang baru; (2) methode: pengiriman laporan belum tepat waktu dibawah standart dan kelengkapan laporan tiap daerah tidak signifikan ; (3) material : sebagian petugas belum memiliki buku panduan salah satunya karena masih terbawa oleh petugas lama dan belum ada surat tugas untuk pendelegasian; (4) money : belum ada alokasi dana; (5) machine : petugas menggunakan handphone dan kendaraan pribadi. Pelaksanaan EWARS belum dapat dikatakan maksimal sehingga perlu adanya monitoring dan evaluasi rutin program di tiap fasyankes tingkat pertama, pendataan SDM untuk pelatihan, perhitungan beban kerja guna pemerataan pekerjaan, adanya SK atau surat tugas sebagai pendelegasian untuk komitmen petugas, adanya umpan balik untuk meningkatkan motivasi serta kesadaran petugas dan pengajuan alokasi dana.
Mapping the ‘home’: A literature review on Filipino migration and diaspora
Authors: Pacoma Marc Agon
Published: July 2020

This article aimed to present a comprehensive literature review on Philippine migration and diaspora. Diaspora is not a new concept for Filipinos; they have been constantly connected to migration, one of the interconnected aspects of the global workforce. Diaspora and migration as common household terms can be traced back from the first overseas Filipino farmworkers in Hawaii in the middle of 1900s to the presently relocated skilled workers and domestic helpers in the Middle East countries and various Asian countries. The author intended to provide a better understanding of existing researches and debates on the topic and evaluate their relationship with the current research study. More so, the essay was intended to identify the research gaps arising from previous scholarly writings, which was beneficial to the author as he embarks in research on Filipino migration and diaspora. Research gaps serve several purposes for the possible direction of future research projects. Most of the literature focused on the reasons of migration; migration narratives and experiences; homeland media consumption; the role of digital technologies and social media in fostering transnational families’ relationships and reinforcing migrant workers’ national and cultural identities. In terms of the approaches, participant observation, interview and digital ethnography were the employed research methodologies.
The role of ethnic culture in social regulation of regional economies
Authors: Madyukova Svetlana A.
Published: July 2020

Social regulation is considered as a soft way of influencing social actors, which presupposes an increase in the role of regional authorities. It has been recorded that using the potential of ethnic culture can be an effective strategy for regulating the economic development of a region. Using the example of the Tuvinian ethnoculture, the paper identifies its specific substantial components that have the potential to increase regional economic indicators. The negative consequences of using the Tuvinian ethnoculture, which are manifested in the value-ethical transformations of ethnic identity, are also recorded. It is concluded that in the region it is necessary to increase the prestige of applied ethnocultural education, intra-regional differentiation of the production of ethnic goods, support for a high quality standards of those components of ethnic culture that have already gained popularity in Russia and across the world.
A Computational and Literature-Based Evaluation for a Combination of Chiral Anti-CoV Drugs to Block and Eliminate SARS-CoV-2 Safely
Authors: Suhail Mohd.
Published: July 2020

It has been a great challenge for the scientists to develop an anti-covid drug/vaccine with fewer side effects, since the coronavirus began. Besides, the mechanism of action and the reason of causing side effects, has also become a great challenge for the scientists in the case of chiral drugs. The main reason behind it, is the prescription of chiral drugs in the racemic form. Another hurdle in front of the world, is the positive test of the patient recovered from coronavirus. Thispositive test of recovered person, shows the demand of such drugs whose mechanism is understandable, and which can block and eliminate SARS-CoV-2 or its material from the body completely, with fewer side effects. The presented computational study explains (i) the mechanism of action of drugs (chloroquine and hydroxychloroquine) that block SARS-CoV-2 (ii) the strength of mefloquine that may eliminate SARS-CoV-2. First, the binding affinities of main protease (Mpro) of JC virus for which mefloquine has already shown its strength to remove, were calculated. After that, same method was applied for SARS-CoV-2, and both the results were compared to know the strength of mefloquine against SARS-CoV-2. Till now, the experimental data found in the literature survey, was neither used in the interpretation nor evaluated computationally, in such a way, as I did for the first time to fight against the pandemicsituation. Hence, the current study includes the docking results and literature data for the prescription of a combination of only biologically active enantiomers to the patient fighting with coronavirus, with less side effect. Two enantiomers that could do it, are S-(+)hydroxychloroquineand (+) mefloquine. Of course, one of these two drugs, will block the coronavirus, while another one will eliminate it.
An Innovative Hydrogen Peroxide-Sensing Scaffold and Insights Towards its Potential as an ROS-Activated Persulfide Donor
Authors: Hankins Rynne , Suarez S. Israel , Kalk Madison , Green Nolan , Harty Megan , Lukesh John
Published: July 2020

Reactive sulfur species, such as hydrogen sulfide, persulfides, and polysulfides, have recently emerged as key signaling molecules and important physiological mediators within mammalian systems. To further assess the therapeutic potential of their exogenous administration, we report on the development of a unique hydrogen peroxide (H2O2)-sensing motif and its capacity for providing cellular protection against oxidative stress while serving as a reactive oxygen species (ROS)-activated persulfide donor. With the strategic implementation of a gem-dimethyl group that promotes both cyclization and stability, we found the initial rate of payload release from this newly derived scaffold to be directly proportional to the concentration of H2O2 and to proceed via an unprecedented pathway that avoids the production of electrophilic byproducts, a severe limitation that has plagued the physiological application of previous designs.
In Silico Exploration of Small-Molecule α-Helix Mimetics as Inhibitors of SARS-COV-2 Attachment to ACE2
Authors: Hakmi Mohammed , Bouricha El Mehdi , Akachar Jihane , Lmimouni Badreddine , EL Harti Jaouad , Belyamani Lahcen , Ibrahimi Azeddine
Published: July 2020

The novel coronavirus, SARS-CoV-2, has infected more than 10 million people and caused more than 502,539 deaths worldwide as of June 2020. The explosive spread of the virus and the rapid increase in the number of cases require the immediate development of effective therapies and vaccines as well as accurate diagnosis tools. The pathogenesis of the disease is triggered by the entry of SARS-CoV-2 via its spike protein into ACE2-bearing host cells, particularly pneumocytes, resulting in overactivation of the immune system, which attacks the infected cells and damages the lung tissue. The interaction of the SARS-CoV-2 receptor binding domain (RBD) with host cells is primarily mediated by the N-terminal helix of the ACE2; thus, inhibition of the spike-ACE2 interaction may be a promising therapeutic strategy for blocking the entry of the virus into host cells. In this paper, we used an in-silico approach to explore small-molecule α-helix mimetics as inhibitors that may disrupt the attachment of SARS-CoV-2 to ACE2. First, the RBD-ACE2 interface in the 6M0J structure was studied by the MM-GBSA decomposition module of the HawkDock server, which led to the identification of two critical target regions in the RBD. Next, two virtual screening experiments of 7236 α-helix mimetics from ASINEX were conducted on the above regions using the iDock tool, which resulted in 10 candidates with favorable binding affinities. Finally, the stability of RBD complexes with the top-two ranked compounds was further validated by 40 ns MD simulations using Desmond package of Schrodinger.
In Silico Investigation on the Binding of Organoselenium Compounds with Target Proteins of SARS-CoV-2 Infection Cycle
Authors: Singh Beena Gobind , Kunwar Amit
Published: July 2020

Since the outbreak of coronavirus disease 2019 (COVID-19), researchers have been investigating the potential of several low molecular weight compounds from both natural and synthetic origins to design anti-viral drugs against SARS-CoV-2. On similar lines, the present study is aimed to evaluate different organoselenium compounds and their sulfur analogues by using a molecular docking approach to inhibit viral proteins like spike (S) glycoprotein (PDB code: 6VXX) and main protease (Mpro) (PDB code: 6LU7) and a host protein, Furin (PDB code: 5MIM), all of which are known to play significant role in SARS-CoV-2 infection cycle. The organoselenium compounds used in the study are mostly in-house synthesized including simple selenium containing amino acids and their derivatives and selenopyridines and their derivatives. The docking calculations were performed using AutoDock Vina. In brief, organoselenium compounds showed stronger binding with the target proteins as compared to their sulfur analogue, except oxidized glutathione. Notably, the most potent docked ligands shared a common structural feature of aromatic amide moieties connected by diselenide bridge. Further, the compounds ebselen diselenide (EbSeSeEb) and nicotinamide diselenide (NictSeSeNict) exhibited the highest binding affinity (in range of ~105 µM-1) to all the above three proteins. Thus, the present investigation highlights the influence of structure and substitution of organoselenium compound on their binding with the SARS-CoV-2 proteins and proposes NictSeSeNict as a candidate molecule for evaluating anti-viral activity against SARS-CoV-2 using preclinical biological models.
A Portable Smartphone-Based Platform with an Offline Image Processing Tool for Rapid Paper-Based Colorimetric Detection of Glucose in Artificial Saliva
Authors: Golcez Tansu , Kilic Volkan , Sen Mustafa
Published: July 2020

Paper-based sensors have great potential for use in a variety of areas, from environmental monitoring to clinical and pointof-care testings. Here, a microfluidic paper-based analytical device (µPAD) was integrated with a smartphone app capable of offline (without internet access) image processing and analysis for rapid colorimetric detection of glucose. A self-inking stamp was used to form hydrophobic channels on a piece of paper-towel due to its superior water absorption efficiency. As demonstrated, the developed sensor was employed for colorimetric detection of glucose in artificial saliva in the linear scope of 0-1 mM with a calculated detection limit of 29.65 µM. In addition, experimental results show that quantitative analysis of glucose with the proposed smartphone platform could be completed in less than one minute. The app developed for the smartphone platform is capable of extracting the color changing area with an embedded image processing tool which could address the problem of color uniformity in detection zones of µPAD. The total cost of a µPAD is less than $0.2. By integrating µPAD with a smartphone and user-friendly app together, the proposed smartphone-based platform could be used for the quantitative analysis of glucose with advantages such as portability, simple operation, rapid response, ultra-low cost, field-deployable, selectivity and sensitivity. The results show that the integrated platform has great potential to be used for non-invasive measurement of glucose in body fluids like a tear, sweat and saliva.
Enhancing Water Sampling in Free Energy Calculations with Grand Canonical Monte Carlo
Authors: Ross Gregory , Russell Ellery , Deng Yuqing , Lu Chao , Harder Edward , Abel Robert , Wang Lingle
Published: July 2020

The prediction of protein-ligand binding affinities using free energy perturbation (FEP) is becoming increasingly routine in structure-based drug discovery. Most FEP packages use molecular dynamics (MD) to sample the configurations of proteins and ligands, as MD is well-suited to capturing coupled motion. However, MD can be prohibitively inefficient at sampling water molecules that are buried within binding sites, which has severely limited the domain of applicability of FEP and its prospective usage in drug discovery. In this paper, we present an advancement of FEP that augments MD with grand canonical Monte Carlo (GCMC), an enhanced sampling method, to overcome the problem of sampling water. We accomplished this without degrading computational performance. On both old and newly assembled data sets of proteinligand complexes, we show that the use of GCMC in FEP is essential for accurate and robust predictions for ligand perturbations that disrupt buried water.
Forcing or Forced Exertions in Amalgamation of Nanoparticles and Particles inside the Solution
Authors: Ali Mubarak , Lin I-Nan
Published: July 2020

The study of forcing or forced exertions in amalgamating or amalgamated nanoparticles and particles inside the solution is important for the scientific societies working in the fields of physical, chemical and mathematical sciences. Observing live dynamics of nanoparticles and particles inside the solution is a challenging task. Again, it is not an appropriate way to discuss amalgamating nanoparticles and particles based only on visualized dynamics. However, suitably captured microscopic images can identify different modes of forcing or forced exertions in amalgamated nanoparticles and particles. Nanoparticles and particles when just at resting positions amalgamate under resultant differences of exerting forces, which are not only related to poles of occupied quadrants, but also related to their own drawn poles. So, colloidal nanoparticles and particles amalgamate from sides experiencing a greater exertion of force. In amalgamation of nanoparticles and particles, the exerted force successively remains in mute, alert and functioning mode. Contrarily, the energy behavior successively remains in functioning, alert and mute mode. Amalgamation of nanoparticles and particles depends on their features and conceived focusing lengths. This is through the resultant differences of exerting forces for two frame of references. Particles of geometrical shapes experience the even exertions of force in their amalgamation, which is not the case for distorted particles. Nanoparticles and particles inside the solution are the best candidates to track nature of exerting forces, and so is the case with energy behaviors, too.
Evaluation of anti-pyretic activity of Dracaena sanderiana by Brewer’s yeast method
Authors: Pavani C H
Published: July 2020

These medicinal plants are used to develop a therapy for the disease. To improve the science, investigate the scientific proof and activities validation, therefore the use of various herbal remedies for their pain-relieving and anti-inflammatory action in these current days. includes influence, anti-inflammatory, anti effect, analgesia, effects and some beneficial effects on the GI system. show the potential value of pain relief, cancer prevention and weight loss. According to these plant effects, consider that this present study was mainly based on to investigate and likely to reduce the fever caused by the outdoor and indoor. potential of is evidenced in leave studies. The medicinal plant produces a variety of chemical substances which shows significant therapeutic properties with the standard drug paracetamol.
Phytochemistry, pharmacognosy and pharmacological profile of Abutilon indicum
Authors: Jubilee R  , Kaviarasu J  , Kishore I  , Keerthana S  , Karthikayan N  , Karthi S
Published: July 2020

Abutilon indicum belongs to the family Malvaceae is known as Indian mallow commonly. The plant was traditionally claimed to possess many medicinal properties and was used in folklore and traditional system s of medicine like Ayurveda. It contains various chemical constituents like flavonoids, phenols, sterols, tannins etc. and was scientifically investigated for many activities like an immune stimulant, dieresis, anti-epileptic, anti-ulcer and anti-parasitic activities. This article reviews the research work that was performed on the plant to publish its phytochemistry, Pharmacognosy and Pharmacological profile of the plant.
Primordial science and pioneering approaches of guggul for chronic ailments – A modernized review
Authors: Jamal Basha D  , Kumar P R  , Ranganayakulu D
Published: July 2020

An oleo gum resin guggulu is a product which obtained as a result of gummosis from the bark of Commiphora wightii (Arnott) Bhandari [syn. Commiphoramukul (Hook. Ex Stocks) Family, Burseraceae]. It has been known for its immense applicability in the Ayurveda since time immemorial for the treatment of variety of disorders such as inflammation, gout, rheumatism, impotence, leprosy, obesity, and disorders of lipids metabolism. It is a mixture of phytoconstituents like terpenoids, steroids, flavonoids, guggultetrols, lignans, sugars, and amino acids. This review is an effort to compile all the information available on all of its chemical constituents which are responsible for its therapeutic potential, limitation of guggul extracts and the necessity of novel principles for gum guggul. Nowadays, Guggul is available as the marketed formulation for curing numerous clinical conditions and is accessible in combination with various other ingredients. Though conventional dosage form shows the dominance as patient compliance and easy availability, yet it has found to pose the problems like dose fluctuation, peak-valley effect, non-adjustment of the administered drug, invasiveness etc. Guggul lacks its desired effect due to its low bioavailability and water solubility. This makes it a partial or a deficient therapy for remedy of many signs and symptoms. Novel drug delivery system (NDDS), a new approach and has excluded many of drawbacks exhibited by conventional dosage forms. Some of the novel dosage forms of guggul has been formed like nanoparticles, nanovesicles, gugglusomes and proniosomal gel. But still, the novel formulations for guggul has its less outspread in the market. Guggul can be executed as a profitable drug using NDDS. There is a need to highlight the unidentified and unexplained facts about guggul so as to make it more efficacious and effective in terms of bioavailability and aqueous insolubility.
Role of Chyavanprashas a Rasayana in combating an outbreak of COVID-19
Authors: Rajni Kamlakar Gurmule
Published: July 2020

Today the whole world is suffering from the most dreadful disease that is Covid 19. The Causative factor for COVID 19 is SARS-COV2. It was ϑirst noticed in Wuhan city of China. World Health Organisation declared the fatality of this disease as a pandemic. This disease has become a problem of great concern globally. This virus targets the respiratory system of human beings. There is a high incidence of person to person transmission of this disease through contact. However, there is also a signiϑicant role in innate immunity in pathogenesis and management of this disease. The whole world is seeking for ϑlawless control of this viral disease. Ayurveda is a holistic science. Its aim is not only on the cure of diseases but also on its prevention. It emphasises mainly on healthy life of an individual. There is a wide range of principles described in Ayurveda which are used to combat disease from its root. Rasayana Chikista is a useful principle of Ayurveda, beneϑicial for management and prevention of many diseases. It is always said that “prevention is better than cure”. Chyavanprash is one of the well known Rasayana. Contents of Chyavanprash shows a wide range of actions on respiratory diseases as well as on boosting immunity. These properties of it provoke us to review the role of Chyavanprash in the prevention of Covid 19, thereby increasing one’s immune response. This Chyavanaprash can be a boon in the prevention of Covid 19 by improving immunity against it.
The Influence of Non-Physical Environment and Performance Appraisal on the Performance Employee Through Work Stress as an Intervening Variable
Authors: Samudri Ayudini , Hamid Nurdjanah , Amar Muhammad Yunus
Published: July 2020

This study aims to determine the direct and indirect effects of the non-physical environment and performance appraisal on the employee performance through work stress as an intervening variable. This research was conducted at the Makassar Branch of Bank Negara Indonesia using a questionnaire fo 85 respondents. The analysis technique using SPSS version 20. The results show that the non-physical environment has a significant effect on work stress. Interestingly, the performance appraisal has no significant effect on work stress, while the work stress has a significant effect on performance. The non-physical environment  and the performance appraisal affects employee performance with work stress as an intervening variable.
Determinant Analysis of Entrepreneurial Orientation in Business Organisations.
Authors: Maharsa Bulky , Kadir Abdul Rahman , Baumassepe Andi Nur
Published: July 2020

The purpose of this study is to analyze the measurement of the entrepreneurial orientation (X) ​​derived from innovativeness, risk-taking, proactiveness, autonomy, and competitive aggressiveness factors. This research is explanatory research with quantitative methods. The population in this study were all food and beverage SME owners in Makassar City. The number of samples was determined as many as 99 respondents with a purposive sampling technique. The data collection method uses a questionnaire. The analytical tool used is partial Least Square (PLS). The results showed that entrepreneurial orientation was measured positively and significantly by Innovativeness. The best indicator for forming an innovativeness variable is X1.1 (focusing on product innovation rather than product/service marketing) because it has the highest loading value. Entrepreneurial orientation is measured positively and significantly by risk-taking. The best indicator forming the risk-taking variable is X2.1 (brave in taking new opportunities despite having a high risk) because it has the highest loading value. Entrepreneurial orientation is measured positively and significantly proactiveness. The best indicator forming the proactiveness variable is X3.2 (being the first compared to competitors in introducing new products and new services) because it has the highest loading value. Entrepreneurial orientation is measured autonomously positively and significantly. The best indicator [form the autonomy variable is X4.3 (has full power in determining the steps to run a business) because it has the highest loading value. Entrepreneurial orientation is measured by competitive aggressiveness in a positive and significant way. The best indicator forming the competitive aggressiveness variable is X5.2 (not afraid to face business competitors) because it has the highest loading value.