bluuebunny/crossref_metadata_2025 huggingface dataset:
SCN1A rs6732655A/T polymorphism: Diagnostic and therapeutic insights for drug-resistant epilepsy
Authors: Viswas Aroop , Dabla Pradeep K , Shrivastav Dharmsheel , Gupta Swapan , Yadav Manisha , Yadav Subhash , Koner Bidhan Chandra
Published: August 2024

BACKGROUND

A significant subset of individuals with epilepsy fails to respond to currently available antiepileptic drugs, resulting in heightened mortality rates, psychosocial challenges, and a diminished quality of life. Genetic factors, particularly within the SCN1A gene, and the pro-inflammatory cytokine response is important in intricating the drug resistance in idiopathic epilepsy cases. In this extended study, we determined the correlation of rs6732655A/T single nucleotide polymorphism to understand the causative association of SCN1A gene with epilepsy drug resistance and inflammatory response.

AIM

To find the correlation of SCN1A gene rs6732655A/T polymorphism with the drug-resistant epilepsy and inflammatory response.

METHODS

The study enrolled 100 age and sex-matched patients of both drug-resistant and drug-responsive epilepsy cases. We analysed the rs6732655A/T polymorphism to study its association and causative role in drug-resistant epilepsy cases using restriction fragment length polymorphism technique. The diagnostic performance of interleukin (IL)-1β, IL-6, and high mobility group box 1 (HMGB1) protein levels was evaluated in conjunction with genotypic outcome receiver operating characteristic analysis.

RESULTS

AT and AA genotypes of rs6732655 SCN1A gene polymorphism were associated with higher risk of drug resistance epilepsy. Serum biomarkers IL-6, IL1β and HMGB1 demonstrated diagnostic potential, with cutoff values of 4.63 pg/mL, 59.52 pg/mL and 7.99 ng/mL, respectively, offering valuable tools for epilepsy management. Moreover, specific genotypes (AA and AT) were found to be linked to the elevated levels of IL-1β and IL-6 and potentially reflecting increased oxidative stress and neuro-inflammation in drug-resistant cases supporting the previous reported outcome of high inflammatory markers response in drug resistance epilepsy.

CONCLUSION

SCN1A genotypes AA and AT are linked to higher drug-resistant epilepsy risk. These findings underscore the potential influence of inflammation and genetics on epilepsy treatment resistance.
Anti-aging based on stem cell therapy: A scoping review
Authors: El Assaad Nassar , Chebly Alain , Salame Rawad , Achkar Robert , Bou Atme Nour , Akouch Khalil , Rafoul Paul , Hanna Colette , Abou Zeid Samer , Ghosn Marwan , Khalil Charbel
Published: August 2024

Stem cells are present in the tissues and organs and remain in a quiescent and undifferentiated state until it is physiologically necessary to produce new descendant cells. Due to their multipotency property, mesenchymal stem cells have attracted considerable attention worldwide due to their immunomodulation and therapeutic function in tissue regeneration. Stem cells secrete components such as paracrine factors, extracellular vesicles, and exosomes which have been shown to have anti-inflammatory, anti-aging, reconstruction and wound healing potentials in many in vitro and in vivo models. The pluripotency and immunomodulatory features of stem cells could potentially be an effective tool in cell therapy and tissue repair. Aging affects the capacity for self-renewal and differentiation of stem cells, decreasing the potential for regeneration and the loss of optimal functions in organisms over time. Current progress in the field of cellular therapy and regenerative medicine has facilitated the evolution of particular guidelines and quality control approaches, which eventually lead to clinical trials. Cell therapy could potentially be one of the most promising therapies to control aging due to the fact that single stem cell transplantation can regenerate or substitute the injured tissue. To understand the involvement of stem cells not only in tissue maintenance and disease but also in the control of aging it is important to know and identify their properties, functions, and regulation in vivo , which are addressed in this review.
IMPACT OF THE RUSSIA-UKRAINE CONFLICT ON INDONESIAN COMMODITY STOCKS: A SYSTEMATIC LITERATURE REVIEW
Authors: Sanoyo Ario Menak , Hidayat Agus Maolana , Firmialy Sita Deliyana
Published: August 2024

The Russia-Ukraine conflict has significantly impacted Indonesian commodity stocks, as revealed by a comprehensive literature review. The conflict has introduced volatility in global markets, directly affecting Indonesian stock commodity-based prices, exchange rates, and investor sentiment. While initial commodity price rises benefited Indonesian stocks, persistent volatility and market interconnectedness pose challenges. This paper employs a systematic literature review methodology, collecting, synthesizing, and analyzing numerous papers published in the last decade on a variety of topics closely related to volatility transmission issues. Based on our review of twenty-seven articles, the result of this paper's analysis underscores the importance of diversifying investments and enhancing resilience against global disruptions. The GARCH models and the Geopolitical Risk Index further emphasize Indonesian commodity stocks' susceptibility to global price fluctuations and geopolitical risks. The research concludes that the Russia-Ukraine conflict has far-reaching consequences for Indonesian stock commodity-based markets, underscoring the need for risk mitigation strategies and enhanced resilience against future geopolitical shocks.
DIVERSITY OF FISH TYPES IN CIRAHAB SOURCE WATER AND WATER QUALITY FOR FISH ECOSYSTEMS IN CIRAHAB, CURUGGOONG VILLAGE PADARINCANG DISTRICT, SERANG-BANTEN
Authors: Hermawan Hermawan
Published: August 2024

The research was conducted at water sources in Cirahab, Curuggoong village, Padarincang District, Serang-Banten Regency, research was conducted in January 2024, this research was conducted to determine the diversity of fish in the water source water ecosystem in Cirahab. The results obtained in the research There are 11 types of fish obtained during the research, including tilapia, goldfish, wader, betook, eel, nilem, chana, tawes, sili-sili, kampala (paitan) and catfish. The fish that dominate the waters of Cirahab are the wader fish which are often found there. Fishing is found in 3 places, namely places number 1, 2 and number 3. The category obtained in the fish diversity index is the "low" category because the value is -1.7255. The water parameters in Cirahab waters are ideal because they have a pH of 7, clarity of 90, water temperature of 23°C and an average depth of only 1 meter.
INCREASING THE ACTIVITY AND OUTCOMES OF SCIENCE LEARNING THROUGH THE IMPLEMENTATION OF THE DISCOVERY LEARNING MODEL IN STUDENT X AT SMK AL KHAIRIYAH CIOMAS
Authors: Hermawan Hermawan , Saefurahman Asep
Published: August 2024

This action research aims to increase student activity and learning outcomes through the application of discovery learning models in class X students at SMK Al Khairiyah Ciomas. The subjects of this research were 30 students in class X. What is used is classroom action research with the Kemmis and Mc model. Taggart. Each cycle is carried out with stages: planning, action implementation, observation and reflection. The results of the analysis of descriptive data show that in cycle I student learning outcomes have not yet reached the minimum completeness criteria (KKM) applied because they have only achieved an average score of 67.60 from a KKM score of 75, and an absorption capacity of 50% which means that 15 students have fulfilled the KKM and 15 students have not reached KKM. This is due to the activeness of students in learning 61.60 while the ability of teachers in learning has only reached 75%. From these results it is necessary to proceed to cycle II. And as for the results of the actions in cycle II that the average student learning outcomes were 76.20, which meant that they had reached the KKM and the absorption was 76.67%, which meant that 23 students had exceeded the KKM. While the ability of teachers by 85%. Because this research had reached KKM, this research was not continued in the next cycle. The results of the study concluded that the application of the discovery learning model can increase the activity and learning outcomes of science.
Analysis of possibilities for stabilizing hydrocarbon production depending on the stage of development
Authors:   V. I. Shpilman Research and Analytical Centre for the Rational Use of the Subsoil, Khanty-Mansiysk, Russia, Pecherin T. N. , Kopytov A. G. ,   V. I. Shpilman Research and Analytical Centre for the Rational Use of the Subsoil, Khanty-Mansiysk, Russia, Levkovich S. V. ,   Industrial University of Tyumen, Tyumen, Russia
Published: August 2024

Of key importance for planning the sustainable development of territories is the potential for stable production of hydrocarbon reserves, which can be expressed by the time of its duration. In the practice of developing oil and gas fields, two methods are known to stabilize production: through geological and technological measures that increase the productivity of wells and by regulating their operating modes. The second method, on the contrary, involves limiting the growth of selections at the initial stage of development. Due to this, the further decline in production turns out to be slower. Accordingly, the need for geological and technological measures is also decreasing. To describe the quantitative characteristics of production stabilization in both cases, a mathematical apparatus has been developed, based on the equations of state of hydrocarbons, the laws of underground hydrodynamics, as well as the work of specialists in the field of analysis and forecasting of the production of hydrocarbon reserves. It has been established that the processes of development of recoverable reserves of both oil and gas are subject to the same laws, and therefore can be described by means of one generalizing equation. Based on the equation, formulas are derived for calculating the duration of a stable production period depending on both the efficiency of intensification technologies and the degree of capacity redundancy, as well as the availability of recoverable reserves and the degree of their production. Calculations of the duration of the stable production stage for specific geological and technological conditions are presented. Keywords: hydrocarbon production; geological and technological measures; operating mode; reserves development.
Pelatihan Perencanaan Pembangunan Desa Seruni Mumbul dalam Rangka Mendorong Pencapaian SDG’s di Lombok Timur
Authors: Anggara Jaka , Fadlli Muhammad Dzul , Singandaru Adhitya Bagus , Handalusia Vici , Wijimulawiani Baiq Saripta
Published: August 2024

Regulations on the use of the budget by the Village Government are constantly changing. These changing regulations require village officials and the community to understand the latest regulations in order to be able to make development budget priorities, including for preparing programs that support the achievement of Sustainable Development Goals (SDG’s). Community Service Activities aim as a forum to provide understanding and knowledge to village officials about (a) the Concept and Definition of SDG's; (b) The role of the village in realizing SDG's; (c) Development planning to realize SDG's. In order to achieve these goals, the solution is to carry out counseling to participants using the lecture method accompanied by discussion. This activity was said to have run well and was successful as assessed by several indicators, namely: (1) The participants who attended were village officials and community leaders had understood the material presented. (2) The village government has a superior development plan in order to encourage the achievement of SDG's. Suggestions regarding this activity are (1) Teams can carry out activities at the same location in the form of development planning technical assistance so that programs can be developed to achieve SDG's; (2) Public participation needs to be increased in development planning.
Meningkatkan Kepercayaan Diri Anak Menggunakan Metode Look and Do
Authors: Fajar Utama Ritonga  , Manda Veronica
Published: August 2024

Childhood is an essential period in human life. Because it is during this period that childrens have strong memories so that they can easily learn and develop from what childrends see and hear. Every human, who is going through growth and development, through various phase and stage in life. From infants, babies, toddlers, children, teenagers and adults. Crucial moments in growth and development lies on the stages of children and teenagers. In the stages of adolescence and adulthood, every child must be equipped. Debriefing children can be done in various ways and methods of learning. Before entering the public environment with peoples, every children must be equipped with a sense of self-confidence to make it easier for children to socialize with the surrounding environment. In hence to achieve,the needs of self-development of children at the Ora Et Labora Nusantara Orphanage, located at Jalan Perkutut No. 44, Central Helvetia, Kec. Medan Helvetia, Medan City, North Sumatra, learning activities are carried out with a system of mutual participation and interaction in each activity. The learning method is called the Look and Do Method. The goal is that every child is able to express himself so that in the development towards adolescence to adulthood each child is equipped with a sense of self-confidence.
Peningkatan Pelayanan Sosial Bidang Rehabilitasi Sosial Dinas Sosial Provinsi Sumatera Utara Secara Adaptif, Responsif, Terstruktur dan Sistematis
Authors: Payandro Doni Saputra Sitanggang  , Berlianti Berlianti , Fajar Utama Ritonga
Published: August 2024

Social services are the duties and responsibilities of a country for existing social welfare problems. Social Welfare Requirements (PPKS) who are individuals, families, groups and/or communities who, due to an obstacle, difficulty or disturbance, are unable to carry out their social functions, so they need social services to meet their needs both physically and spiritually as well as socially adequately and It is natural to have different root causes and problem solving according to the type. The process of re-functionalization and development to enable a person to be able to carry out his social function properly in the life of the community then requires accelerated steps to achieve social rehabilitation itself. Program methods that are adaptive, responsive, structured and systematic will always respond to developments and adjustments to social welfare issues themselves. The Provincial Social Service as the task-bearer to assist the Governor in carrying out government affairs in the social sector and assistance tasks assigned to the Regions are always expected to be able to present an influential and quality accelerated acceleration of social services.
Menumbuhkan Rasa Percaya Diri pada Anak Melalui Permainan Peran Bersama Mahasiswa Kesejahteraan Sosial Fisip USU
Authors: Neni Tresna Juliani Laia  , Tuti Atika
Published: August 2024

Children are the nation's golden generation who will become the cornerstone of a country to be successful or not. During the developmental period of children, it is important for them to gain self-confidence. Good self-confidence will bring children to be able to explore something without feeling ashamed, insecure, or afraid. During the implementation of PKL II conducted by the writer at the Yayasan Panti Asuhan Sosial Bina Mandiri, Medan, the writer found a problem in a group of orphanage children. Confidence is their main problem, this is based on the results of observations of researchers while carrying out work practices. The author hereby seeks to help children to be able to grow their self-confidence, by using the group work method as an approach and in handling it the author applies role playing to encourage children to have self-confidence. The author believes that role play is effective for exploring and bringing back children's self-confidence. The author hopes that this role play can be one of the things that can be done as a way of solving their problems.
Implementasi Permainan Edukasi dalam Meningkatkan Kedisiplinan Anak-Anak di Panti Asuhan
Authors: Nasir Muhidin , Wusqo Urwatil , Hidayat Ali Akbar , Hak Muhamad Bai'ul , Fadlli Muhammad Dzul
Published: August 2024

One of the problems faced by the younger generation today is the problem of discipline. The discipline attitude of children is still far from ideal, such as they do not care about waste, put the clothes in bad ways, often getting up late in the morning, and other problems. Discipline problems occur in almost all parenting conditions. Discipline problems occur in direct parenting by parents, also occur in day care, including in orphanage care. Based on these problems, we want to be actively involved in growing the discipline of children, especially in orphanages. We carry out an educational implementation pattern to develop the discipline attitude of the orphanage children. The method of playing while learning will make children more enthusiastic about participating in the learning process. Playing while learning activities also have the virtue of increasing children's interest as a first step in improving discipline. The stages in this service go through three stages, namely pre-service in the form of observations and interviews related to the problems that occur. The second stage is the implementation of community service in the form of counseling and the implementation of educational games that can improve children's discipline. Furthermore, the third stage is post-service by evaluating the level of discipline of the orphanage children. Based on the activities carried out at the orphanage, the children took part in the program well. As for the results of periodic evaluations conducted, educational activities in improving children's discipline are starting to show positive developments. This is reflected in the attitude of the orphanage children who have started caring to waste, put the clothes in the right place, and getting up early.
Penerapan Hasil Analisis Metode Pekerja Sosial pada Anak Rumah Yatim Medan
Authors: Lukman Nul Hakim Harahap  , Muhammad Farid Anbar  , Putri Gabriella Purba  , Karina Olivia Pricilia Harahap  , Keysha Mumtazah Silalahi
Published: August 2024

This article discusses the methods used by Rumah Yatim social workers in providing services to children in Medan Orphanage.The existence of social workers in an orphanage has a significant meaning for the process of solving problems faced by orphaned children. Social assistance is a strategy that determines the success of community empowerment. Mentoring is also an activity that means coaching, teaching, directing which connotes mastering, controlling, and controlling. The right method will be the initial stage of solving the problems complained by children and the level of efficiency of the method. Orphanage children need a social worker figure as a substitute for the role of parents who should be a place to share problems and a place to get advice as a solution to solve problems. The process of orphanage children in solving problems on their own takes quite a long time considering their immature age. The purpose of this writing is as a result of project base learning activities at the Medan Orphanage Institute. The methods used are observation and interviews in the process of collecting data related to social worker methods. Existing literature sources are also used to support the analysis of the discussion.
Meningkatkan Kesadaran Masyarakat Terhadap Hak-Hak Disabilitas Melalui Mini Project Ramah Disabilitas
Authors: Sinaga Binsar Martua Valentino , Sianturi Chintya Khasanah , Gunawan Danu , Tarigan Rachel Br , Panjaitan Sirana Mikelvania Baby
Published: August 2024

Humans are social beings who crave and desire a healthy and normal life. There are humans who are lucky and should be grateful for being born normally without having any physical or mental disabilities, but there are also humans who are born with both mental and physical disabilities. On the other hand, there are also humans who are born normally and do not have disabilities, but in the course of their lives, there are unintentional accidents that make these humans disabled or disabled. The state is present in protecting and fulfilling the needs of disabilities in various aspects of life. According to Number 8 of 2016 concerning Persons with Disabilities states that persons with disabilities are any person who experiences physical, intellectual, mental and/or sensory limitations for a long time in interacting with the environment may experience obstacles and difficulties to participate fully and effectively with other citizens based on equal rights. The disability-friendly Mini Project aims to increase public awareness and concern for insights about disability such as rights and various public facilities for persons with disabilities. The method used in the disability-friendly mini project includes the stages of preparation, intake and contact, assessment, planning, intervention and program formulation, evaluation and termination.
Meningkatkan Kualitas Belajar Siswa Sekolah Dasar dengan Menggunakan Metode Basik
Authors: Sianturi Lisbet Rizona Br , Ritonga Fajar Utama , Suriadi Agus
Published: August 2024

Education is one of the important aspects in Indonesia's national development. Since Indonesia's independence, the Indonesian government has been committed to expanding access and improving the quality of education throughout the region from Sabang to Merauke. This is done in order to improve the quality of human resources so that they are expected to be prospective successors of the nation. Can carry forward the ideals of the motherland. So it is necessary to further improve the quality of teaching to students. In a teaching system that tends to be monotonous and boring, it becomes a barrier to the development of students' knowledge and interest in learning. The purpose of this writing is to improve the quality of learning of elementary school students using the basik method. The practice location is on Jl. Polonia GG. B, Kec. Medan Polonia, Medan City, North Sumatra. With the focus of the research subject on grade 1 students as many as 12 students. With a period of practice for 4 months. The method used in this practice is the groupwork method proposed by Zastrow with stages consisting of: (1) Engangement, Intake and Contract, (2) assessment, (3) Planning, (4) Intervention, (5) Monitoring, (6) Evaluation, and (7) Termination. The results of this practice show an increase in interest in learning and confidence in students. This is an example of improving the quality of learning.
Optimalisasi Peran Masyarakat dalam Mencegah Kasus Pencemaran Lingkungan Hidup di DAS Meninting Desa Midang
Authors: Taufik Zahratul'ain , Raodah Putri , Handalusia Vici
Published: August 2024

The Meninting River Basin in Midang Village, located in West Lombok Regency, is one of the rivers that has been contaminated by microplastic waste. Therefore, it is deemed necessary to optimize public knowledge regarding the management of waste generated from daily life. This community engagement process goes through four steps. First, by conducting observations of the environmental issues at hand; the second step involves analyzing the problem-solving approach and it is found that there is a need to optimize the role of the community in preserving the environment. The third step is the preparation for the execution of the community engagement, encompassing planning and organizing the implementation of activities. The fourth step is the execution of the community engagement carried out through lectures and discussions, simultaneously disseminating regulations regarding environmental protection and management. This activity subsequently generates new knowledge for the community to be able to manage household waste wisely and economically. The goal of this activity is for residents to spread the acquired information or knowledge to others, in order to create business opportunities for the community and to maintain a cleaner environment.
Penerapan Metode Belajar Partisipatif dalam Meningkatkan Kemampuan Membaca Siswa di SDN 064960 Medan Polonia
Authors: Simanullang Jodis , Fajar Utama Ritonga  , Mia Aulina Lubis
Published: August 2024

In this era of increasingly rapid development and progress, there are so many learning resources and styles that can be applied by teaching staff to increase students' interest in learning and enthusiasm. However, even so, the current learning system still often finds cases where students will just sit listening to the teacher deliver learning material and only follow what is conveyed by the teacher without understanding what the teacher is conveying. Therefore, the teacher is expected to be able to foster students' interest in being directly involved in the learning process. Participatory learning can be interpreted as an effort by educators to involve students in learning activities. Participatory learning activities imply the participation of students in learning activities so that they can achieve the goals of the learning itself. The purpose of this study was to improve students' reading skills at UPT SDN 064960 using a participatory method. This activity is a field work practice in collaboration with campus programs teaching USU partners for approximately four months of assignment. The method used by researchers is a social work method at the mezzo intervention level with a groupwork approach. From the results of the implementation of participatory learning methods in improving students' reading skills, it was concluded that they could achieve predetermined goals in this program, namely increasing students' reading skills.
Analysing the Mathematical Critical and Creative Thinking Abilities in Problem Solving Introverted Students
Authors: Rahayu Nurwanti Adi , Aoyama Kazuhiro
Published: August 2024

This study aims to evaluate the critical and creative thinking abilities in the context of mathematics when solving problems related to arithmetic sequences and series among introverted students in the 11th grade at Xaverius 1 High School in Jambi City. This issue arises due to differences in thinking skills and cognitive processes among students based on personality types, where it was found that introverted students tend to have low mathematical critical and creative thinking abilities. The research method employed is a descriptive qualitative approach, collecting data through personality questionnaires, tests, and interviews. Research subjects were selected from introverted students based on personality questionnaire results and answer sheet analysis, with three students representing the various response groups. The results of this study indicate that introverted students demonstrate good mathematical critical thinking skills in understanding problems, planning, and implementing plans. However, they tend to overlook rechecking their solutions. The creative mathematical thinking abilities of introverted students mainly involve fluency and flexibility in understanding problems, planning, and implementing plans, although they lack in terms of originality and elaboration in problem-solving
Experimental Photography Study by Kurnia Ngayuga Wibowo “Memory Lane”
Authors: Hakim Abdul Aziz Al , A Raden Bima Sakti Arnanda , Andini Rizky Dwi , Imawan Khaerudin , Erawati Dedet
Published: August 2024

The work Experimental Photo Memory Lane by Kurnia Ngayuga Wibowo is a notable piece that has been featured in various prestigious exhibitions, such as "Permata Youth Photostory" organized by Permata Photojournalist Grant and Pannafoto Institute, Bandung Photography Triennale, Bandung Photography Month, and SEA Reading Photobookdummies in Taiwan. This work is considered a masterpiece by Kurnia Ngayuga Wibowo and serves as a compelling example of experimental photography. The appreciation of such a work is often conducted through art criticism, which plays a crucial role in interpreting and appreciating the underlying content of a photographic work. Understanding and interpreting each photograph can vary significantly, depending on the perspective of the critic or the photographer. The purpose of this research is to explore and analyze the artistic elements and intentions behind the Memory Lane series through the lens of art criticism, specifically using Feldman’s art criticism theory. This qualitative study utilizes Feldman’s four-step approach to art criticism-description, formal analysis, interpretation, and evaluation—to gain a deeper understanding of the photography series. The findings of this research reveal that Memory Lane represents a form of experimental photography, which navigates various challenges inherent to the medium, particularly in terms of storytelling through images. The study demonstrates how art criticism can provide diverse perspectives on a single work of art and how these perspectives can be integrated with other art forms to enrich the overall interpretation. The implications of this research extend to the broader field of art criticism and photography, highlighting the importance of critical analysis in understanding the multifaceted nature of photographic art and its capacity to convey complex narratives.
Analisis Tingginya Penjualan Album KPop Dalam Pertumbuhan Ekonomi di Indonesia
Authors: Yuliawan Rahmat , Sudarnice Asia , Windaputri Nessa , Aurelly Kyra Prudence
Published: August 2024

This study aims to determine the high sales of K-pop albums on economic growth, identify factors that contribute to high sales of K-pop albums, understand how the popularity of K-pop in Indonesia affects consumer spending patterns, explain the role of social media and online platforms in promoting K-pop album sales in Indonesia. The study uses a mixed method by combining quantitative and qualitative approaches. Quantitative data were obtained from official sources such as the Central Bureau of Statistics and reports on K-pop album sales in Indonesia. While qualitative data were collected through in-depth interviews with stakeholders in the music industry, such as distributors, music stores, and K-pop fans. The results of the study found several interesting things including The Courtship, The Relationship, The Marriage, Kpop Album Marketing Strategy Through Online Media and the Influence of Album Quality on the Interest in Buying Physical Kpop Music Albums Quality.
Pengaruh Pemasaran Online Terhadap Minat Beli Konsumen Pada Toko Jingga
Authors: Nini Nini
Published: August 2024

This research aims to determine whether or not there is an influence of online marketing strategies on consumer buying interest at Toko Jingga. This research uses quantitative methods and uses questionnaires as a tool to collect data. The number of respondents in this research was 100 respondents using purposive sampling technique. The data analysis technique used in this research is simple linear regression analysis using SPSS 25. The results show that online marketing strategies have a positive and significant influence on consumer buying interest at Toko Jingga. This research provides a theoretical impression as a reference for further research related to online marketing and consumer buying interest, especially in online stores. Managerial implications in the form of suggestions for the management of Toko Jingga and other marketplaces to improve product quality and the promotional system used in marketing products so as to increase consumer buying interest.
Pengaruh Harga, Kualitas Pelayanan Dan Kualitas Produk Terhadap Kepuasan Konsumen Berbelanja Pada Djaros Swalayan Jati Pariaman
Authors: Eldhani Gufran , Yanti Novi , Zaki Zaki
Published: August 2024

This study aims to determine the effect of price, service quality and product quality on consumer shopping satisfaction at Djaros Swalayan Jati Pariaman partially and simultaneously. This research was conducted in Kota Pariaman using primary and secondary data, with multiple linear analysis techniques. Based on the partial results (T test) the price variable (X1) is 0.005 <0.05, the service quality variable (X2) is 0.002 <0.05 and the product quality variable (X3) is 0.004 <0.5 which means it has a significant influence on satisfaction Consumer (Y) Shops at Djaros Swalayan Pariaman. Simultaneously (F test) Fcount value 3.408 > FT table 2.70 and Sig. 0.021 is less than <0.05 which means it has a significant effect simultaneously on shopping satisfaction (Y) at Djaros Supermarkets. The value of the coefficient of determination symbolized R2 (R-Square) is 0.584, in other words, the large percentage of variation in Consumer Satisfaction (Y) of Djaros Swalayan Pariaman can be explained by variations of the three independent variables, namely Price (X1) Service Quality (X2) and Product Quality (X3) of 58.40% while the remaining 41.60% is explained by other variables outside of this research.
The effectiveness of using visual communication in teaching vocabulary to non-English majors students at the Foreign Languages Center of Nguyen Tat Thanh University
Authors: Kien Tran Trung
Published: August 2024

Due to the essence of English vocabulary learning and its challenges, teachers tend to be in search of effective pedagogical techniques. The current case study aims to explore the usefulness of visual media in teaching vocabulary at Nguyen Tat Thanh University. A total of 240 non-English majors completed an online survey to express their opinions on using visual media in vocabulary class. Findings revealed the benefits, such as interesting learning conditions, stronger word memorization, improved learning strategies, high contexts for word practice, and convenient word meaning presentation. The perceived reasons were interesting, memorable content, different kinds of visualizations, interactive and extensive exercises, and the use of many senses. The results have a few applications to EFL vocabulary teaching and learning at the university. This study could make contributions to future studies as its findings delineated that visual media adapted from the coursebook can facilitate students’ vocabulary learning and foster their learning motivation.   
® 2024 Journal of Science and Technology - NTTU
Định lượng đồng thời các hợp chất axit ascorbic, acetaminophen, phenylephrin HCl, guaifenesin, dextromethorphan HBr trong thuốc viên bằng phương pháp sắc ký lỏng hiệu năng cao
Authors: Thảo Nguyễn Thị Thu , Nhàn Mai Thanh
Published: August 2024

Nghiên cứu thực hiện với hai mục tiêu: xây dựng và thẩm định quy trình định lượng đồng thời axit ascorbic, acetaminophen, phenylephrin HCl, guaifenesin, dextromethorphan HBr ở dạng thuốc viên bằng phương pháp sắc ký lỏng hiệu năng cao (HPLC), và ứng dụng quy trình đã thẩm định để định lượng một số mẫu trên thị trường có chứa các hợp chất trên. Việc phân tách sắc ký được thực hiện trên cột pha đảo C18 (250 mm × 4,6 mm, 5 μm), dùng kiểu rửa giải gradient với pha động A (đệm photphat pH = 3,0) và pha động B (acetonitril). Kết quả nghiên cứu thu được khoảng nồng độ tuyến tính lần lượt axit ascorbic, phenylephrin HCl, acetaminophen, guaifenesin và dextromethorphan HBr là (8-56, 16-104, 40-240, 16-80 và 24-146) μg∙mL−1. Độ đúng phương pháp được xác định bằng tỷ lệ phục hồi trong khoảng (98,80-101,27) %. Độ lặp lại có phần trăm độ lệch chuẩn tương đối (% RSD) là 0,64 % (< 2,0 %). Phương pháp đề xuất có thể áp dụng để định lượng sáu loại thuốc viên đang lưu hành trên thị trường, và cả sáu mẫu thuốc đều đạt hàm lượng theo quy định Dược điển Việt Nam V.
® 2024 Journal of Science and Technology - NTTU
Vai trò của trạng thái chánh niệm trong mối quan hệ giữa áp lực công việc và sự mệt mỏi cảm xúc - Nghiên cứu tại các doanh nghiệp ở TP.HCM
Authors: Tú Trần Hoàng Cẩm
Published: August 2024

Nghiên cứu này tập trung khảo sát vai trò trung gian của trạng thái chánh niệm trong mối quan hệ giữa hành vi gây áp lực tại nơi làm việc (hay còn gọi là bắt nạt nơi công sở) và sự mệt mỏi về mặt cảm xúc của nhân viên. Dựa trên lý thuyết bảo tồn nguồn lực, nghiên cứu đề xuất mô hình trong đó hành vi gây áp lực tác động tiêu cực đến trạng thái chánh niệm, làm suy giảm nguồn lực tinh thần của nhân viên. Thông qua khảo sát 300 nhân viên tại các doanh nghiệp trên địa bàn TP.HCM và phân tích bằng phần mềm PLS-SEM 4.0, kết quả nghiên cứu cho thấy trạng thái chánh niệm đóng vai trò trung gian quan trọng và hành vi gây áp lực tại công sở đã làm tăng đáng kể sự mệt mỏi về mặt cảm xúc đồng thời làm suy giảm trạng thái chánh niệm của nhân viên. Vì vậy, để nâng cao sức khỏe tinh thần và hiệu suất công việc của nhân viên, việc đạt trạng thái chánh niệm và sử dụng các biện pháp ngăn chặn hành vi gây áp lực tại nơi công sở trở thành vấn đề cấp thiết của mỗi đơn vị.
® 2024 Journal of Science and Technology - NTTU
The Implementation of Mind Mapping in Reading Narrative Text for Eight Graders
Authors: Rahmadina Indy , Kurniati Ruri Fadhilah
Published: August 2024

The purpose of this study is to describe the learning process using mind mapping on reading narrative text material and student's perceptions of the use of mind mapping. Data collection was carried out in July 2023 in class VIII-A of Al-Muayyad Middle School Wates Kedensari Tanggulangin and totalled 8 students. This study uses qualitative descriptive research. The instruments used in this study were observation, interviews, and documentation. Researchers used observation techniques to obtain data during the mind-mapping learning process on reading narrative text material in class. Students gave a positive response to the use of mind mapping in class. The results of the interview showed that most students thought that the use of mind mapping could have a positive impact because felt interested in learning and found it easier to understand the material.
Tujuan dari penelitian ini adalah mendeskripsikan proses pembelajaran menggunakan mind mapping pada materi reading narrative text dan presepsi siswa terhadap penggunaan mind mapping. Pengambilan data dilakukan pada bulan Juli 2023 di kelas VIII-A SMP Al-Muayyad Wates Kedensari Tanggulangin dan berjumlah 8 siswa. Penelitian ini menggunakan penelitian deskriptif kualitatif, Instrumen yang digunakan dalam penelitian ini adalah observasi, wawancara dan dokumentasi. Peneliti menggunakan teknik observasi untuk memperoleh data pada saat proses pembelajaran mind mapping pada materi reading narrative text dalam kelas. Siswa memberikan respon positif pada penggunaan mind mapping di kelas. Hasil wawancara menunjukan sebagian besar siswa beranggapan bahwa penggunaan mind mapping dapat memberikan dampak positif karena mereka merasa tertarik untuk belajar, dan lebih mudah memahami materi.
Avaliação de redes neurais deep learning para a classificação de Câncer de mama
Authors: Barros Maria Eduarda Santana da Silva , Lins Robson Cavalcanti , Rodrigues Iago Richard
Published: August 2024

A visão computacional trata da extração de informações das imagens e da identificação e classificação de objetos presentes nessa imagem. Dentre as áreas de aplicações da visão computacional podem-se citar: robótica, cidades inteligentes e medicina. Na medicina, diagnósticos médicos podem ser auxiliados com o uso de imagens capturadas por raios x, tomografia computadorizada, ressonância magnética e ultrassonografia. Vários campos da medicina têm se beneficiado com o aprimoramento de diagnósticos por meio de imagens, em particular, a oncologia. Com o crescimento da utilização do aprendizado de máquina para tomada de decisão em diversas aplicações reais, a forma de realização da análise de exames de imageamento com aplicações clínicas para o auxílio na tomada de decisões têm se tornado uma solução viável. As aplicações clínicas que utilizam uma abordagem baseada em redes neurais de aprendizado profundo podem determinar com alta precisão se o paciente está saudável, com tumor maligno ou benigno. Nesse contexto, este trabalho realiza uma avaliação modelos de redes neurais de aprendizagem profunda para classificação de câncer de mama utilizando exames de imageamento. Os resultados foram alcançados a partir da realização de avaliação de desempenho de diversas redes neurais, considerando ajustes na primeira arquitetura utilizada e modelos pré-definidos da biblioteca keras. As simulações mostram que o primeiro modelo construído e parte de suas variações, bem como os modelos resnet152v2 e inceptionresnetv2, adotados para a análise comparativa, atingiram a acurácia de 97,72% na classificação do câncer de mama.
Educação inclusiva e tecnologias emergentes: análise dos cursos EAD de licenciatura em letras libras sob as perspectivas de vantagens, desvantagens e futuro
Authors: Bezerra Erich Teles , Lima Isaac Felipe dos santos , Vieira Andréia Jacobina Fonseca , Gonçalves Silvana Aparecida Borges , Sousa Douglas Barbosa , Damacena Rosana , Lisboa Angélica de Oliveira Caçador , Lima Larissa Corsino , Silva Giselly Nascimento da , Freitas Romulo Goes , Pinheiro Juliana Monteiro , Monteiro Arlice Lopes , Abrantes Jucelino da Silva
Published: August 2024

Este estudo examina a eficácia dos cursos de Licenciatura em Letras Libras na modalidade Educação a Distância (EAD), enfocando a inclusão educacional de estudantes surdos no Brasil. A pesquisa justifica-se pela necessidade de adaptar a educação superior às especificidades linguísticas e culturais dos surdos, considerando as limitações e oportunidades oferecidas pelo ensino a distância. O objetivo é analisar o impacto das tecnologias digitais na aprendizagem de Libras e identificar os desafios enfrentados na adaptação dos conteúdos e na formação de professores. Adotou-se uma abordagem bibliográfica, revisando literatura acadêmica e documentos institucionais, com triangulação metodológica para garantir a consistência dos dados. Os resultados indicam que, apesar dos avanços significativos, os cursos EAD enfrentam desafios como a necessidade de adaptar recursos educacionais e a importância da formação contínua dos professores. As tecnologias digitais oferecem oportunidades valiosas para enriquecer a aprendizagem e promover a inclusão linguística. Conclui-se que é essencial investir em materiais didáticos acessíveis e na capacitação dos educadores para melhorar a educação inclusiva.
Fatores para a legitimidade de organização de título de capitalização na modalidade filantropia premiável
Authors: Oliveira Leonardo de , Seibert Rosane Maria , Brum Emanuelle Ferreira , Callegaro Ana Rita Catelan
Published: August 2024

O objetivo deste artigo foi identificar os fatores que contribuem para consolidar e expandir a legitimidade da organização que detém os direitos do título de capitalização da modalidade filantropia premiável Tri Legal Tchê. Para atingir o objetivo revisou-se a legitimidade organizacional, suas abordagens, seus tipos e desafios. Também se revisou a reputação e os públicos de interesse das organizações que são os responsáveis pela legitimação delas. Os métodos da pesquisa foram classificados quanto aos fins em pesquisas aplicada e descritiva; e quanto aos meios em pesquisa de campo, com aplicação de um questionário aos públicos de interesse e estudo de caso, por meio de observações não participante na organização Tri Legal Tchê. Pelos resultados foi possível elencar os fatores que podem contribuir com a manutenção e expansão da legitimidade organizacional. Observou-se que a organização já é conhecida nas cidades onde atua e conta com uma boa aceitação da população. Portanto, se considerou que a organização está legitimada pelos seus stakeholders podendo avançar para a ampliação desta legitimidade, com atitudes coerentes com o que se espera dela. Além de manter as atividades que desempenha com a mesma eficiência e eficácia, precisa atender aos interesses identificados na pesquisa, como, criar uma plataforma digital para negociações online, de divulgação do antes e depois dos premiados e da sua parceria com a Federação das APAEs. Organizações que destinam parte dos seus resultados para fins filantrópicos, precisam evidenciar para terem reconhecimento dos seus stakeholders, e consequentemente uma maior aceitação dos seus produtos.
Estudo das variações de temperatura de um laboratório universitário
Authors: Oliveira Amanda Fernandes de , Santos Gabrielly de Souza dos , Silva Syndel Flavia Lopes da , Oliveira Lucas Prado de Jesus , Jabur Andrea Sartori , Conte Viviane Cristhyne Bini
Published: August 2024

O artigo tem como objetivo, o estudo das oscilações de temperatura que ocorrem no Laboratório de Ambiental/Saneamento, localizado na Universidade Tecnológica Federal do Paraná – Campus Apucarana. Esta pesquisa foi realizada pelos alunos do curso de engenharia civil, a qual são usuários do laboratório, em projeto educacional. As medições ocorreram nos períodos das 8 horas da manhã às 16 horas, onde ocorre a utilização do local. A metodologia consistiu na instalação de dois termômetros digitais, com a medição da temperatura interna, um sensor de temperatura externa e a medição das paredes interna e externas, com o uso do termômetro infravermelho. Obteve-se temperaturas, umidades e temperaturas das paredes, e fez-se a análise gráfica durante os períodos estudados. Concluiu-se o quanto é necessário o estudo do conforto térmico pelos profissionais da área, pois é de muita importância para promover o conforto dos usuários e no laboratório estudado são necessárias soluções que possam adaptar o ambiente construído aos seus usuários, já que no período matutino as temperaturas chegam a níveis mais elevados em comparação os das temperaturas externa, causando desconforto, identificado por reclamações de usuários quanto à sensação térmica e a  geração de danos em equipamentos laboratoriais.
Importance of brassinosteroid in soybean yield
Authors: Amorim Víctor Alves , Furtado Brunno Nunes , Parreira Gabriel Sartin , Lima Gabriel Henrique Ferreira de , Valadão Weslley Ayres , Filho Lino Carlos Borges , Borges Larissa Pacheco , Matos Fábio Santos
Published: August 2024

The aim of the present study was identify the effects of brassinolide plant regulator in soybean plants yield. The work was carried out at Olhos d’água farm located in Ipameri, Goiás, Brazil. It was used the Pioneer TEC 7022 IPRO with six brassinolide concentrations (0, 0.025, 0.050, 0.075, 0.1 and 0.125 ml L-1) of a pre-prepared solution and pulverized with a 100 L ha-1 flow rate. The applications were executed in R3 and R6 stages. The experiment was carried out following the completely randomized design with five replications. Each experimental plot was set up with 18x222 meters, with 0.5 meters between lines and 11 plants per linear meter. The brassinolide applications in R3 and R6 stages with 0.072 ml L-1 concentration increased the yield in 25.1%. Brassinolide increase the grains sink-source relationship and change the assimilates partition to reproductive development (pods number, grain number, grain weight per plant and yield) instead of vegetative growth, without compromising absorption of soil solution.