bluuebunny/crossref_metadata_2025 huggingface dataset:
Assessing the Relationship Between Gravidity and Placental Malaria Among Pregnant Women in a High Transmission Area in Ghana
Authors: Akinnawo Ayodele , Seyram Kaali , Kaali Ellen Boamah , Harrison Samuel , Dosoo David , Cairns Matthew , Asante Kwaku Poku
Published: December 2021

Background

Malaria infection during pregnancy can cause significant morbidity and mortality to a pregnant woman, her foetus and newborn. In areas of high endemic transmission, gravidity is an important risk factor for infection, but there is a complex relationship with other exposure-related factors, and use of protective measures. This study investigated the association between gravidity and placental malaria (PM), among pregnant women aged 14-49 in Kintampo, a high transmission area of Ghana.
Methods

Between 2008-2011, as part of a study investigating the association between PM and malaria in infancy, pregnant women attending antenatal care (ANC) clinics in the study area were enrolled and followed up until delivery. The outcome of PM was assessed at delivery by placental histopathology. Multivariable logistic regression analyses were used to investigate the association between gravidity and PM, identify other key risk factors, and control for potential confounders. Pre-specified effect modifiers including area of residence, socio-economic score (SES), ITN use and IPTp-SP use were explored.
Results

The prevalence of PM was 65.9% in primigravidae, and 26.5% in multigravidae. After adjusting for age, SES and relationship status, primigravidae were shown to have over three times the odds of PM compared to multigravidae, defined as women with 2 or more previous pregnancies (adjusted OR=3.36 (95% CI 2.39-4.71), N=1808, P<0.001). The association appeared stronger in rural areas (OR for PG vs. MG was 3.79 (95% CI: 3.61-5.51) in rural areas; 2.09 (95% CI: 1.17- 3.71) in urban areas; P for interaction =0.07), and among women with lower socio-economic scores (OR for PG vs. MG was 4.73 (95% CI 3.08-7.25) amongst women with lower SES; OR=2.14 (95% CI 1.38-3.35) among women with higher SES; P for interaction =0.008. There was also evidence of lower risk among primigravidae with better use of the current preventive measures IPTp and LLIN.
Conclusions

The burden of PM is most heavily focused on primigravidae of low SES living in rural areas of high transmission. Programmes should prioritize primigravidae and young women of child-bearing age for interventions such as LLIN distribution, educational initiatives and treatment to reduce the burden of malaria in first pregnancy.
Clinical Audit of Two Standard Surgical Site Treatments Following Dental Extractions and The Impact on Incidence of Alveolar Osteitis Within a Specialist Dental Clinic
Authors: Dakin Myles , Aspinall Richard , Kenny Thomas
Published: December 2021

Background

Alveolar osteitis is a painful condition following dental extraction associated with absence of blood clot and consequent exposure of underlying alveolar bone. It is a condition whose exact aetiology is unresolved and a known complication in up to 30-40% of dental extractions. The following report details a retrospective evaluation of two approved, long-standing wound care treatments used, post-extraction, within our clinic to assess for relationship with alveolar osteitis incidence.
Methods

Patients undergoing non-acute dental extraction at a dental out-patient clinic in the UK had received two different standard treatments for a period from 2000 to 2014. The treatments were mouth rinse with physiologic saline or surgical site irrigation and mouth rinse with physiologic saline-low dose aqueous chlorine used in wound and burn-site care. Retrospective, post-operative outcome analysis suggested improved outcomes with one of the standard treatments versus the other. A full retrospective audit of consecutive treatment outcomes was implemented to test the hypothesis. The audit data-collection was blinded to the treatment administered and to the identity of the treating clinician. Statistical analysis was carried out independently and blinded to the treatment modality.
Results

All patients were routinely reviewed within seven days and a determination of un-complicated healing vs alveolar osteitis (requiring further intervention) was made. Our results show that treatment with of aqueous chlorine in physiological saline significantly reduced the incidence of alveolar osteitis versus the control group who received physiologic saline without socket irrigation and chlorhexidine oral rinse home-care. (Odds Ratio 0.0146 Relative Risk 0.029 (95%CI 0.0093 to 0.0928) significance (p<0.001).
Conclusions

This is the first report to show an extremely significant reduction in the incidence of alveolar osteitis following treatment with low dose aqueous chlorine in physiological saline compared with those receiving the physiologic saline and saline mouth rinse or Corsodyl mouth rinse. This shows an approach to surgical site care is superior to the most common, reported, standard of care treatment. The impact of this has led to improved antibiotic stewardship within the clinic for dental extraction or elective oral surgery, including third molars.
Potential Role of CTNNA3 and FRMPD4 in Vascular Thrombosis of Colon Adenocarcinoma
Authors: Liu Bin , Xiang Yu , Guo Weihua
Published: December 2021

Background: Vascular tumor thrombus is an important pathological feature of malignant tumors, closely related to lymph node metastasis, and considered to be tumor micrometastasis. Two down-regulated genes, Catenin Alpha 3 (CTNNA3) and FERM And PDZ Domain Containing 4 (FRMPD4) were selected via analyzing the differential expression of vascular tumor thrombus in colon adenocarcinoma and paracancerous tissues. Furthermore, we observed the potential role of them in vascular thrombosis of colon adenocarcinoma.Method: Candidate genes for vascular thrombosis of colon adenocarcinoma were screened by GSE127069, and then pan-cancer verification and immune infiltration analysis were performed. The relationship between gene and vascular thrombosis was analyzed from the level of gene mutation by cBioPortal. Finally, the clinical samples collected were used for expression verification.Results: CTNNA3 and FRMPD4 were low-expressed in vascular tumor thrombus of colon adenocarcinoma, which were positively correlated with microsatellite instability (MSI). They were also closely related to immune microenvironment and immune cell subtype infiltration. According to the analysis of gene mutation, their gene deletion was related to the vascular invasion indicator. Finally, the protein and mRNA expression of CTNNA3 and FRMPD4 were down-regulated in the samples of vascular thrombosis of colon adenocarcinoma, compared with the normal glands which from paracancerous tissues.Conclusion: Our study demonstrates that CTNNA3 and FRMPD4 may be potential biomarkers of vascular thrombosis in colon adenocarcinoma. These results may provide a new strategy to identify the micrometastasis in colon adenocarcinoma.
MiR-146a-5p and miR-191-5p are the Candidates for Novel Diagnostic Markers of Ovarian Clear Cell Carcinoma
Authors: Takamizawa Shigeatsu , Kojima Junya , Umezu Tomohiro , Kuroda Masahiko , Hayashi Shigehiro , Maruta Takenori , Okamoto Aikou , Nishi Hirotaka
Published: December 2021

Background: Ovarian cancer is a malignant gynecologic disease rarely diagnosed in the early stages. Among ovarian cancers, clear cell carcinoma has a poor prognosis due to its malignant potential. MicroRNAs (miRNAs) regulate gene expression in cells by suppressing the translation of the target gene or by degrading the target mRNA. They are also secreted from the cells in the blood, binding to the proteins or included in extracellular vesicles lipids and assisting in cell-cell communication. Hence, the serum miRNAs can also be diagnostic biomarkers for ovarian cancer. This study investigated and identified specific miRNAs for ovarian cancer clear cell carcinoma and compared them to those of the ovarian endometrioma in healthy controlpatients. Results: CA125, an ovarian tumor marker, did not differ between ovarian clear cell carcinoma, endometriosis, and healthy controlsthe three groups. Four miRNAs (miR-146a-5p, miR-191-5p, miR-484, and miR-574-3p) were analyzed. The miR-146a-5p and miR-191-5p expression levels were significantly increased in the serum samples from the ovarian clear cell carcinoma subjects compared to the healthy controlscontrols, but not in the subjects with endometriosis (P < 0.05). Furthermore, the bioinformatics analysis showed that CCND2 and NOTCH2 were the candidate target genes of miR‑146a-5p and miR-191-5p.Conclusions: Our results showed that miR‑146a-5p and miR-191-5p might be useful as an early and non-invasive diagnostic tool in ovarian clear cell carcinoma. These miRNAs can help in distinguishing between ovarian clear cell carcinoma and ovarian endometrioma. To the best of our knowledge, no studies have screened any candidates specifically for clear cell carcinoma.
Does Conventional Morphological Evaluation Still Play a Role in Predicting Blastocyst Formation?
Authors: Jiang Xiaoming , Cai Jiali , Liu Lanlan , Liu Zhenfang , Wang Wenjie , Chen Jinhua , Yang Chao , Geng Jie , Ma Caihui , Ren Jianzhi
Published: December 2021

BackgroundAdvanced models including time-lapse imaging and artificial intelligence technologies have been used to predict blastocyst formation. However, the conventional morphological evaluation of embryos is still widely used. The purpose of the present study was to evaluate the predictive power of conventional morphological evaluation regarding blastocyst formation.MethodsRetrospective evaluation of data from 15613 patients receiving blastocyst culture from January 2013 through December 2020 in our institution were reviewed. Generalized estimating equations (GEE) were used to establish the morphology-based model. To estimate whether including more features regarding patient characteristics and cycle parameters improve the predicting power, we also establish models including 27 more features with either LASSO regression or XGbosst. The predicted number of blastocyst were associated with the observed number of the blastocyst and were used to predict the blastocyst transfer cancellation either in fresh or frozen cycles. ResultsBased on early cleavage and routine observed morphological parameters (cell number, fragmentation, and symmetry), the GEE model predicted blastocyst formation with an AUC of 0.779(95%CI: 0.77-0.787) and an accuracy of 74.7%(95%CI: 73.9%-75.5%) in the validation set. LASSO regression model and XGboost model based on the combination of cycle characteristics and embryo morphology yielded similar predicting power with AUCs of 0.78(95%CI: 0.771-0.789) and 0.754(95%CI: 0.745-0.763), respectively. For per-cycle blastocyst yield, the predicted number of blastocysts using morphological parameters alone strongly correlated with observed blastocyst number (r=0.897, P<0.0001) and predicted blastocyst transfer cancel with an AUC of 0.926((95%CI: 0.911-0.94). ConclusionThe data suggested that routine morphology observation remained a feasible tool to support an informed decision regarding the day of transfer. However, models based on the combination of cycle characteristics and embryo morphology do not increase the predicting power significantly.
Acceptance and hesitancy to receive COVID-19 vaccine among university students in Egypt: a nationwide survey
Authors: Tharwat Samar , Saad Ahmed Mohammed , Nassar Mohammed Kamal , Nassar Dalia Kamal
Published: December 2021

Background: The public's willingness to be vaccinated will determine the success of the COVID-19 vaccination programme. The aim of this study was to identify acceptance and hesitancy to receive COVID-19 vaccine among university students in Egypt, assess their level of knowledge about COVID-19 vaccine and identify barriers for hesitancy to uptake of COVID-19 vaccine.Methods: This cross-sectional survey study included 1071 university students. A standardized and self-administered questionnaire was constructed by the authors and distributed to university students allover Egypt.Results: Of the 1071 respondents, 739 (69%) were willing to get vaccinated against COVID-19 while 223 (20.8%) reported vaccine hesitancy. Median knowledge score of participants about COVID-19 vaccine was 4 out of 8 (IQR=8). While fear of getting infected (53.6%) and desire to get back to normal life (51%) were the main motives for intention to get vaccinated, fear of serious side effects (100%) and doubting the efficacy of COVID-19 vaccine (60.5%) were the main reasons for vaccine hesitancy and resistance. About 21% of students (n=225) reported voluntary uptake of COVID-19 vaccine. Conclusion: We identified rates of COVID-19 vaccine acceptance and hesitancy and detected poor knowledge scores among university students which may hinder vaccine acceptance. We also detected poor translation of vaccination intention into actual vaccine uptake. Educational campaigns and efforts aiming to raise awareness about safety and efficacy of COVID-19 vaccines need to be directed to this important population.
Crop Field Classification using Data Fusion of Unmanned Aerial Vehicle (UAV) and Sentinel 2A satellite: the case of Oda Dhawata Kebele Cluster farmland, Oromia Region, Ethiopia
Authors: Demelash Melkamu , Tesfaw Binyam , Tibebe Degefie
Published: December 2021

Accurate crop classification using remote sensing based satellite imageries approach remains challenging due to mix in spectral signatures. Employing Unmanned Aerial Vehicle (UAV) together with satellite imageries is believed in improving crop classification at field. Accordingly, this study aims to evaluate the potential of UAV images by blending with Sentinel 2A satellite images for crop field classification in Ethiopian agricultural context. The main purpose of the blending is to upgrade and or improve the lower resolution of the data source that is the sentinel 2A data which was 10m resolution. In the study, UAV data was used and preprocessed. The preprocessing includes camera calibration, photo alignment, dense point cloud generation based on the estimated camera positioning of scouting crop types. Then, orthomosaic UAV image was generated from single dense point cloud. Then, the processed UAV data was fused with Sentinel 2A (medium resolution) satellite data using Gram Schmidt pan sharpening method.this method is the most approach that it can run large data sets of spatial resultions. For crop classification, the Random forest (RF) machine-learning algorithm and Maximum likelihood methods were applied. Apart from the UAV and S2A data, field data was collected for training the crop classification. The point field data was collected from Teff, Wheat, Faba bean, Barley and Sorghum crop fields The results show that RF classifier algorithm classifies the crop types with 94% overall accuracy whereas the Maximum likelihood classifier with 90% overall accuracy. This implies that fused image has a potential to be used for crop type classification together with relatively better classification technique with high accuracy level
The association between female reproductive tract microbiota and recurrent pregnancy loss: a nested case-control study
Authors: Peuranpää Pirkko
Published: December 2021

Objective
To study the associations of endometrial and vaginal microbiota with recurrent pregnancy loss (RPL).
Design
A nested case-control study.
Setting
Helsinki University Hospital, Finland.
Population
Women with two or more consecutive pregnancy losses (n=47) and healthy control women without a history of pregnancy loss (n=39).
Methods
The endometrial and vaginal microbiota compositions, analysed using 16S rRNA gene amplicon sequencing, were compared between RPL women and controls, and between individual vaginal and endometrial samples. The mycobiota composition was analysed using internal transcribed spacer 1 amplicon sequencing for a descriptive summary. The models were adjusted for confounding variables BMI, age, and parity, and FDR-corrected P-values (q-values) were used to define nominal statistical significance at q < 0.05.
Main outcome measures
Mean relative microbial abundances.
Results
Lactobacillus crispatus was less abundant in the RPL endometrial samples compared to controls (mean relative abundance 17.2% vs. 45.6%, q = 0.04). Gardnerella vaginalis was more abundant in RPL women than in controls in both endometrial (12.4% vs. 5.8%, q < 0.001) and vaginal samples (8.7% vs. 5.7%, q < 0.01). The individual vaginal and endometrial microbial composition correlated strongly (R = 0.85, P < 0.001). Fungi were detected in 22% of the endometrial and 36% of the vaginal samples.
Conclusions
Unfavourable reproductive tract microbiota was associated with RPL and may represent a novel risk factor for pregnancy losses.
Saving Species in a Snap: On the Feasibility and Efficacy of Augmented Reality-based Wildlife Interactions for Biodiversity Conservation
Authors: Pimentel Daniel
Published: December 2021

Interactions with wildlife can contribute to biodiversity conservation outcomes, though safety and accessibility considerations limit animal encounters from being a viable strategy. This investigation explores the feasibility of mobile augmented reality to facilitate interactions with wildlife and encourage biodversity conservation. A mobile augmented reality experience (Snapchat lens), titled “Penguin Rescue!”, was created to allow users to rehabilitate an oil-slicked virtual penguin. Study 1 distributed the lens globally to Snapchat users (N=63,605) who spent an average of 47 seconds rehabilitating the penguin; psychographic data showed pro-environmental interests were not associated with the lens’ use. Study 2 employed a within-subjects experimental design (N=80) to examine the effects of Penguin Rescue! on conservation outcomes. Results showed that the interaction increased connectedness with the species. Moreover, social presence and plausibility served as key mechanisms contributing to environmental concern and behavioral intentions. Overall, results clarify how biophilic interactions via augmented reality can benefit biodiversity conservation.
Family Sports Interventions for the Treatment of Obesity in Childhood: A Meta- A Nalysis
Authors: Hong YANG li , xu Tang li , Na Yu Yao , Qian Xiao , mao Xi mao
Published: December 2021

Background Obesity in children has become one of the key concerns of the World Health Organization (WHO), and the incidence of related non-communicable diseases is also rising.Objective This study evaluates the effect of family sports participation on the treatment and prevention of obesity in children aged 0–14 years old by systematic analysis.Study Design Systematic analysis;Level of Evidence,4.Date Extration according to PRISMA-IPD (Preferred Reporting Items for MetaAnalyses of individual participant data) guidelines.The two researchers independently assessed the risk and bias of the articles, obtained a comprehensive, high-quality result,and extracted the data based on the Cochrane intervention system review manual.Data Sources The databases used to search for literature are Google Scholar,CNKI, VIP, Scopus, Embase, SpringerLink, Sciencedirect, Cochrane Library, Wanfang, PubMed, and Web of Science. The last document search date was November 6, 2020.Study Selection Selection criteria following:Randomized controlled trials (RCTs) were selected from the searches that used family sports interventions or family sports combined with dietary adjustments and behavioral habits change. Only studies targeting overweight or obese children aged 0–14 years were included.Main Results The search resulted in a total of 16 studies. Across all 16 studies, there were a total of 1,680 participants in the experimental groups and 1,701 participants in the control groups. The results are as follows:body mass index (BMI)(SMD-RE = -4.10, 95% CI (-0.84 ~ 0.02), Z = 1.88, P = 0.06); Body weight (SMD-RE = -0.77, 95% CI (-1.53 ~ -0.01), Z = 2.00, P = 0.05); Waist circumference (SMD-RE = -0.45, 95% CI (-1.36 ~ 0.47), Z = 0.96, P = 0.34); Body fat rate (SMD-FE = -0.06, 95% CI (-0.22 ~ 0.11), Z = 0.69, P = 0.49). Hence, through family sports intervention among obese children, juvenile and obese body composition—BMI, body weight, waist circumference, and body fat rate—are all reduced.Conclusions Compared with the samples without family sports, the weight, BMI, body fat rate and waist circumference of obese children participating in family sports decreased
Intraseasonal variability of global land monsoon precipitation and recent change
Authors: Liu Fei , Wang Bin , Ouyang Yu , Wang Hui , Qiao Shaobo , Chen Guosen , Dong Wenjie
Published: December 2021

Accurate prediction of global land monsoon rainfall on a subseasonal (2-8 weeks) time scale has become a worldwide demand. Current forecasts of weekly-mean rainfall in most monsoon regions, however, have limited skills beyond two weeks. Given that two-thirds of the world’s population lives in the monsoon regions, this challenge calls for a more profound understanding of monsoon intraseasonal variability (ISVs). Our comparison of individual land monsoons shows that the high-frequency (HF; 8-20 days) ISV, crucial for the Week 2 and Week 3 predictions, accounts for about 53-70% of the total (8-70 days) ISV in various monsoons, and the low-frequency (LF; 20-70 days) ISV has a relatively high contribution over Australia (AU; 47%), South Asia (SA; 43%), and South America (SAM; 40%) monsoons. The leading modes of HFISVs in Northern Hemisphere (NH) monsoons primarily originate from convectively coupled equatorial Rossby waves (Asia), mixed Rossby-gravity waves (North America, NAM), and Kelvin waves (northern Africa, NAF), while from mid-latitude wave trains for Southern Hemisphere (SH) monsoons and East Asian (EA) monsoon. The Madden-Julian Oscillation (MJO) directly regulates LFISVs in the Asian-Australian monsoon while affecting the American and African monsoons by exciting Kelvin waves and mid-latitude teleconnections. During the past four decades, the HF (LF) ISVs have considerably intensified over the Asian (Asian-Australian) monsoon but weakened over the American (SAM) monsoon. Subseasonal-to-seasonal (S2S) prediction models do exhibit higher subseasonal (Weekly 2-Weekly 4) prediction skills over SA, AU, and SAM monsoons that have larger LFISV contributions than the other monsoons. The results suggest an urgent need to improve the simulation of convectively coupled equatorial waves and two-way interactions between regional monsoon ISVs and mid-latitude processes and between MJO and regional monsoons, especially under the global warming scenarios.
Timing and Rates of Two Products Using Hydrogen Peroxide (H2O2) to Control Algae in Ebb and Flow Hydroponic Systems
Authors: Thakulla Dharti , Dunn Bruce L. , Goad Carla , Hu Bizhen
Published: December 2021

Algae is not desirable in hydroponics and creates problems such as reduced yield and decreased dissolved oxygen, and affects the physiology of plants and, thus, needs to be controlled. An experiment was conducted in Ebb and Flow hydroponic systems to investigate the application timing and rates of two hydrogen peroxide products (Zerotol and PERpose Plus). Treatments included 35 mL weekly, 35 mL biweekly, 70 mL weekly, 70 mL biweekly, and a control with no application of hydrogen peroxide using a 40-gallon reservoir of water. Pepper ‘Early Jalapeno’ and ‘Lunchbox Red’ and tomato ‘Geronimo’ and ‘Little Sicily’ were used. The study was conducted in a split-plot design with two replications over time. Plant growth parameters, including plant height, flower number, net CO2 assimilation, fresh weight, and dry weight were recorded. Algae data, including dry weight, algae cell counts, and chl a were also measured. Results indicated that with increasing rate and timing of either product decreased algae counts, dry weight, and chl a values. However, weekly and biweekly application of 70 mL of both products were not different for algae quantification. In pepper, plant height, shoot fresh and dry weight, and root fresh and dry weight were found to be significantly greater with Zerotol 35 mL biweekly, Zerotol 70 mL weekly, PERpose Plus 35 mL biweekly, and PERpose Plus 70 mL weekly compared with the control. ‘Lunchbox Red’ was significantly greater than ‘Early Jalapeno’ in all growth parameters, except soil plant analysis development (SPAD). ‘Lunchbox Red’ had the greatest flower number, with weekly application of 70 mL PERpose Plus. In tomato, greatest flower number and SPAD were observed in ‘Geronimo’ with a weekly application of 70 mL PERpose Plus and 70 mL Zerotol, respectively. Greater shoot and root fresh and dry weight for both tomato cultivars were recorded with 35 mL biweekly or 70 mL weekly application with either product. The results from both plants as well as algae analysis suggest that weekly application of 70 mL of either Zerotol or PERpose Plus produced the best results in terms of controlling algae and improving the growth of pepper and tomato plants.
A STUDY TO ASSESS THE EFFECTIVENESS OF PLANNED TEACHING PROGRAMME REGARDING STEM CELLS AMONG ELIGIBLE COUPLES IN SELECTED AREAS OF AHMEDABAD
Authors:   Principal, Apollo Institute of Nursing, Gandhinagar, Gujarat, India., Mohan Singh Hari , Patel Hina ,   Assistant Professor, Apollo Institute of Nursing, Gandhinagar, Gujarat, India., Chaudhari Hemangi ,   Assistant Lecturer, Apollo Institute of Nursing, Gandhinagar, Gujarat, India., D Group ,   Students, Apollo Institute of Nursing, Gandhinagar, Gujarat, India.
Published: December 2021

Introduction: Stem cells have tremendous promise to helping us to understand and treat a range of various diseases, injuries and other health related conditions. Their potential is evident in the use of cord blood stem cells to treat diseases of the blood, A cord blood stem cells therapy has saved the lives of thousands of children with leukemia and can be seen in the use of stem cells for tissue grafts to treat diseases or injury to the bone, skin and surface of the eye. Materials and Methods: This pre-experimental study was conducted on eligible couples with sample size of age between 15-45 years, willingness to participate in study in selected areas of Ahmedabad. The investigator adopted purposive technique to select sample. Data was collected using 4 demographic variables & 20 questionnaires regarding stem cells, its uses, diseases treated by stem cells & stem cell banking were included. A pre-test was conducted on 40 samples after which the planned teaching programme was implemented followed by the post test. Result: Data gathered was analyzed and interpreted using both experimental and inferential statistics. The mean and SD of pre-test was 5.725 and 1.3957, whereas the mean and SD of post- test was 16.25 and 1.1036, the calculated t value was greater than tabulated t value. Hence the null hypothesis was rejected and the research hypothesis was accepted. The result shows that when planned teaching program was given to eligible couples age group people, they achieve the best scores. Conclusion: This Study intends to assess the effectiveness on plan teaching program regarding stem cells among eligible couple in selected areas of Ahmedabad. This Study reveals that the post-test knowledge score is higher than the pre-test knowledge score regarding stem cells storage, stem cells banking among the eligible couple.
EXPERIMENTAL STUDY OF THE ENERGY PERFORMANCE OF NANSU STOVE WITH A MODIFIED GRID BY THE CONTROLLED COOKING TEST
Authors:   National University of Science, Technology, Engineering and Mathematics (UNSTIM)., C. Wilfrid Adihou , Christophe Awanto ,   University of Abomey - Calavi (UAC)., G. Gladys Milohin ,   University of Abomey - Calavi (UAC)., C. Aristide Houngan ,   National University of Science, Technology, Engineering and Mathematics (UNSTIM)., Malahimi Anjorin ,   University of Abomey - Calavi (UAC).
Published: December 2021

The present work concerns the modification of the grid of the Nansu stove, used in many households in Africa and in particular in Benin. The performance of the stove obtained (modified Nansu) was estimated and compared on the one hand with that of the corresponding reference stove and on the other hand with that of the ordinary Nansu stove. To do this, the Controlled Cooking Test (CCT) was used to determine the specific fuel consumption and cooking time for three dishes, namely rice, beans and voandzou. The results of these tests show that the modified Nansu fireplace is significantly more economical, in terms of fuel consumption and cooking time, compared to the ordinary Nansu fireplace. The savings made by the modified Nansu stove compared to the ordinary Nansu stove are 34.57% to 64.31% in specific consumption and 9.42% to 37.81% in cooking time depending on the type of dish.
MARKETING BEHAVIOUR OF JASMINE GROWERS IN DINDIGUL DISTRICT OF TAMIL NADU
Authors:   Assistant Professor (Agricultural Extension), Horticultural College and Research Institute, Periyakulam-625604., Vanetha K.P.
Published: December 2021

Jasmine flower is used for various purposes viz. making garlands, bouquets, decorating hair of women, religious offerings etc. Scientific cultivation of jasmine is one of the important prerequisites for increasing the production and productivity among the jasmine growers. Since the crop requires huge manpower for harvesting and other operations, only small farmers are cultivating the crop. In general, it is felt that studies on marketing behaviour of jasmine growers is neceessary. Hence, the present study was undertaken with the objective to study the marketing behaviour of Jasmine growers in Nilakottai block of Dindigul district. The respondents were selected based on proportionate random sampling method. The data were collected from respondents through pre-tested interview schedule. The results of the study revealed that majority of the respondents received full payment and it is seen that 76.60 per cent of the respondents sold their produce in the markets. More than two-fifths of the respondents considered the immediate payment as the main criteria for the selection of market followed by receipt in advance (10.00%). 53.30 % growers sell their produce with middle man involvement. Majority of the respondents reported that existing marketing facilities were not sufficient and the rest 40.00% and 60.00% were satisfied with the existing market facilities.
APPRAISAL OF ENERGY CONSUMPTION AND CARBON DIOXIDE EMISSIONS ON FIXED CAPITAL FORMATION IN NIGERIA
Authors:   Department of Banking and Finance, University of Nigeria, Nigeria., Igoni Suoye , Anthony Nwadioha Nnaemeka ,   Department of Banking and Finance, University of Nigeria, Nigeria., R. Odi Ebi ,   Department of Finance and Banking, University of Port Harcourt, Nigeria.
Published: December 2021

There is growing interest for the use of renewable energy and carbon dioxide emission in Nigeria, and the world over.Despite the volume of consumption, and the enabling oil and gas laws to protect the environment and improve the well-being of citizens over the years, the gross fixed capital formation have not received a remarkable growth in Nigeria which motivated for this study. The gross fixed capital formation was the dependent variable against energy consumption, and carbon dioxide emission that represented the explanatory variables were sourced from the World Bank and the Central Bank of Nigeria Statistical Bulletin between 1985-2014. The study adopted the Augmented Dickey-Fuller and the Autoregressive Distributive Lag model for the analysis. The data were integrated at levels and first order differenced. The Johansen cointegration test indicated co-integrating equations in long run. Furthermore, the error correction found energy consumption to be positive, while carbon dioxide emission had a negative but insignificant impact on the Nigerian fixed capital formation. The study recommended the ministry of environment to enforce the existing oil and gas laws, and advocate for the use of modern energy in rural areas of Nigeria.
PHYTOCHEMICAL SCREENING, TOTAL POLYPHENOLS AND FLAVONOIDS CONTENT AND ANTIRADICAL ACTIVITY OF METHANOLIC EXTRACT OF ANNICKIA CHLORANTHA FROM GABON
Authors:   Departement de Pharmacologie. Universite des Sciences de la Sante (USS), BP : 4009 Libreville (Gabon)., Grace Ombouma Joanna , Abogo Mebale Aime-Jhustelin ,   Laboratoire Pluridisciplinaire des Sciences (LAPLUS), Ecole Normale Superieure (ENS), BP :17009, Libreville (Gabon)., Mefouet Abessolo Daniel-Datch ,   Laboratoire Pluridisciplinaire des Sciences (LAPLUS), Ecole Normale Superieure (ENS), BP :17009, Libreville (Gabon)., Abessolo Mve Ornella ,   Laboratoire Pluridisciplinaire des Sciences (LAPLUS), Ecole Normale Superieure (ENS), BP :17009, Libreville (Gabon)., Mboma Raymonde ,   Departement de Biologie et dEcologie Vegetale. Institut de Recherche en Ecologie Tropicale (IRET), BP : 13354, Libreville (Gabon).
Published: December 2021

In traditional medicine, Annnickia chlorantha (Annonaceae)is used in many parts of Africa to treat several pathologies. It is used for the management of stomach problems, for the treatment of jaundice, tuberculosis, urinary tract infections, malaria, hepatitis and ulcers forms, for gallstones or even diarrhea. The phytochemical analysis and determination of the antiradical activity of the methanolic extract of the trunk bark from Annickia chlorantha from Gabon was the subject of this study. Phytochemical screening revealed the abundance of alkaloids, polyphenols and catechics tannins.The total polyphenol content released by the Folin-Ciocalteu method was 309.17 Â± 38.05 g of gallic acid equivalent per 100 mg of dry matterand the total flavonoids content performed with AlCl3 was 155.16 Â± 21.06 g of quercetin equivalent per 100 mg of dry matter. The antiradical activity was limited to 81.58% Â± 1.25 without disappearance of the ABTSâ€¢+ radical after 6 minutes of incubation. These results confirm the correlation between the polyphenol content and the antiradical activity.
CONTEMPT OF COURT IN THE PERSPECTIVE TO DO NOT IMPLEMENT DECISION OF ADMINISTRATIVE
Authors: Soplanit Miracle , D. Bakarbessy Andress , S. Alfons Saartje
Published: December 2021

The purpose of research is to knowing how the construction of contempt of court on the action that is not implementing the court ruling of administrative court. The method of research is yuriction normative which is using the approach of legal norm and conceptual approach . This Research done with analyzing the primarily and secondary of legal material. Result of research is showing that contempt of court consists of the aspect of criminal insult and civil insult . Civil insult cover all activities that is not implementing the court ruling , so its not implementing court decision of administrative which has been have the power of permanent law is also categorized as action of contempt of court.
ANTI-PYRETIC AND ANTI-INFLAMMATORY ACTIVITY OF AQUEOUS EXTRACT OFSOLANUM XANTHOCARPUM BERRIES IN SUITABLE ANIMAL MODELS
Authors:   Department of Pharmacology, Regional Institute of Medical Sciences, Imphal, Manipur, Pin code: 795004, India., Tarinita Devi Leisangthem , Medhabati Devi Mayanglambam ,   Department of Pharmacology, Regional Institute of Medical Sciences, Imphal, Manipur, Pin code: 795004, India., Lalvarmawi Florence ,   Department of Physiology, Regional Institute of Medical Sciences, Imphal, Manipur, Pin code: 795004, India., Datta Swagata ,   Department of Pharmacology, Regional Institute of Medical Sciences, Imphal, Manipur, Pin code: 795004, India.
Published: December 2021

Background: Use of traditional medicines for treating various diseases have become a topic of global importance because of their safety, less side effects and cost-effectiveness. The present study was undertaken to evaluate the anti-pyretic and anti-inflammatory activity of aqueous extract of Solanum xanthocarpum berries (SXB) in suitable animal models. Methods: Anti-pyretic activity was assessed by dried yeast induced pyrexia in rats. Anti-inflammatory activity was evaluated using carrageenan induced paw oedema in rats. Three doses of the plant extract (500, 1000 and 1500 mg/kg) prepared by dissolving the drugs in 2% gum acacia were used. Paracetamol 33 mg/kg and aspirin 100 mg/kg were used as standard drugs for anti-pyretic and anti-inflammatory activity respectively. Vehicle served as a control drug. Results: Acute toxicity study results demonstrated no mortality of animals after 24 hours. The aqueous extract of the plant significantly decreased the rectal temperature of the rats and significantly prevented increase in volume of paw oedema. Conclusion: The aqueous extract of Solanum xanthocarpum berries exerts its anti-pyretic and anti-inflammatory activity activity. However, further studies with the plant are required to evaluate the dose dependent activity and also to determine the active principle responsible for exact mechanism for both antipyretic and anti-inflammatory activity.
SEVERE COMBINED IMMUNODEFICIENCY SCREENING AND STEM CELL TRANSPLANT-AN ECONOMIC EVALUATION SCHEME
Authors:   Consultant of Family Medicine & Public Health, Ministry of Health, Jeddah, Saudi Arabia., Ahmed Alzobaidi Husain , Rhman Alghamdi Abdul ,   Associated Professor of Family Medicine, Taif University, Taif, Saudi Arabia., Eid Mahfouz Mohammad ,   Laparoscopic and Thoracic Surgeon, Taif University, Taif, Saudi Arabia., Dakeel Allah Alsubhi Rawan ,   General Practitioner, King Abdullah Medical Complex, Ministry of Health, Jeddah, Saudi Arabia.
Published: December 2021

Background: Severe Combined Immunodeficiency (SCID) is a rare genetic disease that affects newborn immune system and costs healthcare system a substantial amount of money. Screening and stem cell transplant may offer a cost-effective alternative to the current medical practice. Objective: To determine the cost-effectiveness of screening newborn for SCID with subsequent stem cell transplant versus standard of care. Materials and Methods: An economic evaluation was proposed, using Treeage software on a set of evidence-based propabilities and variables. Outcomes: as shown on the tree, we count the death from SCID. Its given the payoff 1, while the survival is payoff 0. The outcome of interest is death averted by screening live birth and implementing subsequent stem cell transplant for those who tested +ve.
MUGHALKINGDOM IN INDIA ACCORDING TO HAMKAS SEJARAH UMAT ISLAM
Authors:   Research Centre for Arabic Language and Islamic Civilization, Faculty of Islamic Studies, Universiti Kebangsaan Malaysia, 43600 UKM Bangi, Selangor, Malaysia., Zulfazdlee Abul Hassan Ashari Mohamad , Roslan Mohd Nor Mohd ,   Department of Islamic History and Civilization, Academy of Islamic Studies, Universiti Malaya, 50603Kuala Lumpur, Malaysia., Lubis Safian Nursafira ,   Department of Arabic Language and Literature, KIRKHS, International Islamic University of Malaysia, Jalan Gombak, 53100 Kuala Lumpur, Malaysia., Hafiz Safiai Mohd ,   Research Centre for Sharia, Faculty of Islamic Studies& Institute of Islam Hadhari, Universiti Kebangsaan Malaysia, 43600 UKM Bangi, Selangor, Malaysia., Zainal Hakim ,   Research Centre for Arabic Language and Islamic Civilization, Faculty of Islamic Studies, Universiti Kebangsaan Malaysia, 43600 UKM Bangi, Selangor, Malaysia., Azraai Jamsari Ezad ,   Research Centre for Arabic Language and Islamic Civilization, Faculty of Islamic Studies, Universiti Kebangsaan Malaysia, 43600 UKM Bangi, Selangor, Malaysia.
Published: December 2021

India is important in the study of Islamic history and civilization research as it was one of the earliest territories that received Islamic preaching and was the site for various Islamic kingdoms until the year 1857. The achievements of Islamic civilization in India, particularly during the Mughal era, added sparkle to the glory of Islamic history. For this reason, the facts relating the Mughal Kingdom in India have been discussed in writings on Islamic history and civilization, including the book, Sejarah Umat Islam, by Hamka. The purpose of this article is to study Hamkas work on the history of the Mughal Kingdom in India and analyse the narration and discussion he submitted. This research adopts a qualitative approach using historial study and content analysis to gather and analyse data. Research results find that Hamka had the interest and knowledge in writing Islamic history by describing Muslim societies and Islamic states from their inception to their end, including the Mughal Kingdom in India. In his narrative of Mughal history, Hamka inserted the element of teaching or ibrah (lesson), particularly when discussing the time of Mughal decline. The narrative approach is consistent with the philosophy of Islamic history that stresses on the ibrah concept, which was meaningful to Hamkas own personality as a missionary. Hence, his work, SejarahUmatIslam, proved Hamkas ability to discuss Islamic history, and simultaneously resonated with readers interested in issues of Islamic history.
Creative accounting and its influence on corporate performance and financial reporting: A case study of Kosovo
Authors: Abdurrahmani Enis , Doğan Zeki
Published: December 2021

As it is known, Kosovo is a newly established and developing country. Naturally, creative accounting practices in Kosovo are becoming more frequent due to gaps and weaknesses in management and audit quality. This study aims to examine the relationship between creative accounting and corporate performance and management, as well as the impact of managers’ ethics including audit period on financial reporting and creative accounting limitation. The study adopted a survey-based approach. The questionnaires were distributed among 159 managers, auditors, and head accountants. Linear regression was used to analyze the hypotheses. The research results confirmed the rejection of the first hypothesis, as the mean is less than 3 (the average on a five-point Likert scale). The results confirmed that creative accounting has a significant impact on corporate performance. The results also confirmed the second hypothesis as the mean is greater than 3.5 (the average on a five-point Likert scale). Thus, managers’ ethics have a significant effect on the reliability of financial statements. In addition, the research results confirmed the acceptance of the third hypothesis, as the mean is greater than 3 (the average on a five-point Likert scale), thus there is a positive influence of the audit period on creative accounting limitation. The study found a negative impact of creative accounting on corporate performance. Furthermore, a significant effect of managers’ ethics on financial statements’ reliability was concluded; and finally, the findings concluded that audit period and quality could significantly contribute to the creative accounting limitation.
Cardioprotective effects of fetal kidney-derived mesenchymal stem cells on doxorubicin-induced cardiotoxicity in rats
Authors: YAVUZ ORHAN , ÖZGERMEN BAŞAK BOZTOK , HAYDARDEDEOĞLU ALI EVREN , DINÇEL GÜNGÖR ÇAĞDAŞ
Published: December 2021

Cardiotoxicity is one of the most common side effects of doxorubicin (DOX), a chemotherapy drug used in the treatment of many carcinomas. In recent years, stem-cell therapies have been successfully used to prevent cardiotoxicity. This study investigated the efficacy of intraperitoneally administered fetal kidney-derived mesenchymal stem cells (FKD-MSCs) in preventing DOX-induced cardiotoxicity in rats. For this purpose, thirty rats were randomly divided into three groups: control, DOX and mesenchymal stem cell (MSC) groups. Adriamycin was injected as a single dose via the tail vein in the DOX and MSC groups in order to induce cardiotoxicity. FKD-MSC was applied to the MSC group by the intraperitoneal route after cardiotoxicity had been established. Then the rats were euthanized, and routine histological procedures were performed on their hearts. H&E and Masson’s stains were used for histopathology. Cardiac Troponin-T and I (cTnT, cTnI), Caspase-3 and BCL-XL antibodies were used for immunohistochemistry. Vacuoles, edema, degeneration and necrosis were observed histopathologically mostly in the DOX group. Lesions in the control and MSC groups were less severe. Fibrosis in the control and MSC groups was milder. cTnT and cTnI immunopositive staining was most commonly seen in the control group, followed by the MSC group. Immunohistochemical staining by Caspase-3 and BCL-XL showed that their expressions in the MSC group were statistically similar to those in the control group. Accordingly, it was concluded that the intraperitoneal application of MSC had a positive effect on histopathological findings, fibrosis, immunohistochemistry, especially apoptosis, neovascularization, and anti-apoptotic development, whereas troponin levels were not found to be therapeutic.
Effectiveness of Bacillus subtilis (Vitafort) probiotic used for raising broiler chickens
Authors: FAIRUSHIN RIFKAT , SHAKIROVA SVETLANA , GANIEVA RIMMA , SHAKIROVA GALIYA
Published: December 2021

Unbalanced nutrition as well as diseases of infectious and non-infectious etiology lead to a decrease in production and a significant loss of farm animals and birds. To mitigate these problems, various probiotic drugs (probiotics) are introduced into the diets of birds and animals for preventive purposes. The aim of the research was to study the effect of the Vitafort probiotic, containing antagonistic bacteria of the endophytic strain Bacillus subtilis B11, on the body of broiler chickens. The effect of Vitafort was assessed by measuring the live weight and average daily growth of birds. In addition, a morphological study of blood was carried out and the content of Bacillus subtilis in the small intestine was determined. It was found that the endophytic strain Bacillus subtilis B11 improved the intestinal microflora. Thus, on day 5 of its use, the number of microorganisms varied from 4.1 × 104 to 8.2 × 104 CFU/g, and on day 42 the same number varied from 4 × 108 to 5.8 × 108 CFU/g on day 42, the contents of red blood cells, haemoglobin, and white blood cells in the blood of chickens from the experimental group were higher by 6.44%, 3.44%, and 2.11%, respectively, than they were in the control group. Considering the above facts, it can be assumed that the absorption of nutrients in the intestine improved, and metabolic processes were activated due to an increase in the transport abilities of red blood cells.
Application of high throughput sequencing in veterinary science
Authors: GIZA ALEKSANDRA , IWAN EWELINA , WASYL DARIUSZ
Published: December 2021

High throughput sequencing (HTS) creates an opportunity for comprehensive genomic studies. It can be applied in veterinary science, bacteriology and virology, diagnostics of animal diseases, food safety, examinations of the composition of environmental samples, and even in veterinary vaccinology. Thus HTS a wide-ranging method that can be applied in different areas of the One Health approach. In particular, the whole genome sequencing (WGS) of bacteria is routinely used in food hygiene and outbreak investigations for phylogenetic analysis of pathogenic bacteria isolated from various sources across timeline, molecular characterisation of bacteria, plasmids, antibiotic resistance and identification of virulence factors. Metagenomics can be used to characterize the composition of microbiota in environmental samples. It makes it possible to obtain a taxonomic identification of bacteria, fungi or plants present in a metasample. It can also be used for the monitoring and epidemiological tracing of viruses, such as SARS-CoV-2. The transcriptomic approach makes it possible to study the expression of genes associated with various infections and diseases. HTS is a highly versatile method, but the selection of the proper application is crucial to obtain expected outcomes. The paper presents some HTS approaches and examples of research in veterinary science.