bluuebunny/crossref_metadata_2025 huggingface dataset:
Recent Developments in Nonsteroidal Antiinflammatory Drugs in Cats
Authors: Carroll Gwendolyn L. , Simonson Stephanie M.
Published: September 2014

Pain, particularly chronic pain, is an underestimated ailment in cats. Veterinarians tend to under-diagnose and under-treat pain in this aloof and stoic species. Until recently, there was only one analgesic (i.e., butorphanol) approved in the United States for use in cats; but many analgesics, particularly opioids, have been used extra-label for this purpose. Nonsteroidal antiinflammatory drugs (NSAIDs) have been used sparingly in cats because of safety concerns, which are less of an issue with the newer agents. Meloxicam is the only NSAID labeled for use in cats in the United States, but other agents are available in this country and are labeled for use in cats in other countries.
Use of Compounded Adrenocorticotropic Hormone (ACTH) for Adrenal Function Testing in Dogs
Authors: Kemppainen Robert J. , Behrend Ellen N. , Busch Katherine A.
Published: September 2014

Serum cortisol concentrations were measured in five healthy dogs in response to five adrenocorticotropic hormone (ACTH) preparations. Cortisol concentrations were similar at time 0 (pre-ACTH) and at 30 and 60 minutes after injection of all forms of ACTH. However, at 90 and 120 minutes post-ACTH, serum cortisol concentrations were significantly lower following injection of two compounded forms of ACTH. The data showed that injection of four compounded forms of ACTH caused elevations in serum cortisol concentrations of a similar magnitude as cosyntropin in samples collected 60 minutes after administration; but concentrations at later times varied, depending on the type of ACTH used.
The Effect of Ingredients in Dry Dog Foods on the Risk of Gastric Dilatation-Volvulus in Dogs
Authors: Raghavan Malathi , Glickman Nita W. , Glickman Lawrence T.
Published: September 2014

Using dry dog food label information, the hypothesis was tested that the risk of gastric dilatation-volvulus (GDV) increases with an increasing number of soy and cereal ingredients and a decreasing number of animal-protein ingredients among the first four ingredients. A nested case-control study was conducted with 85 GDV cases and 194 controls consuming a single brand and variety of dry food. Neither an increasing number of animal-protein ingredients (P=0.79) nor an increasing number of soy and cereal ingredients (P=0.83) among the first four ingredients significantly influenced GDV risk. An unexpected finding was that dry foods containing an oil or fat ingredient (e.g., sunflower oil, animal fat) among the first four ingredients were associated with a significant (P=0.01), 2.4-fold increased risk of GDV. These findings suggest that the feeding of dry dog foods that list oils or fats among the first four label ingredients predispose a high-risk dog to GDV.
Comparison of Complications of Percutaneous Endoscopic Versus Surgically Placed Gastrostomy Tubes in 42 Dogs and 52 Cats
Authors: Salinardi Brenda Jo , Harkin Kenneth R. , Bulmer Barret J. , Roush James K.
Published: September 2014

Dogs and cats that had a percutaneous endoscopic gastrostomy (PEG) tube or surgically placed gastrostomy (SPG) tube inserted were retrospectively analyzed to compare complication rates and the severity of complications. Complication rates and severity scores were not significantly different when the PEG tube group was compared to the SPG tube group in either dogs or cats. Only when data from dogs and cats were combined did PEG tubes have a significantly higher complication rate and significantly greater complication severity scores.
Dietary-Related Skeletal Changes in a Shetland Sheepdog Puppy
Authors: McMillan Chantal J. , Griffon Dominique J. , Marks Steven L. , Mauldin Glenna E.
Published: September 2014

A commercially available, renal failure diet was used to manage suspected renal failure in a 10-week-old Shetland sheepdog puppy. Rickets subsequently developed, possibly from low phosphorous intake and an increased calcium to phosphorus ratio. Decreased dietary calcium in addition to decreased phosphorus may have played a role in decreasing bone mineral density. Lethargy, decreased long bone growth, angular limb deformity, and osteopenia occurred, but these signs resolved within 3 months with nutritional management.
Canine Oral Malodor
Authors: Eubanks Diana L.
Published: September 2014

Canine oral malodor may be the first indication that a serious disease process is occurring in the oral cavity. Various methods for detecting oral malodor have been used in humans, and some of these are suitable for collecting data in the dog. Oral malodor often responds favorably to improved oral hygiene, administered first by a trained professional and followed with adequate home care.
Bone and Lean Tissue Changes Following Cranial Cruciate Ligament Transection and Stifle Stabilization
Authors: Francis David A. , Millis Darryl L. , Head Laurie L.
Published: September 2014

Following cranial cruciate ligament transection and extracapsular stabilization, dual-energy X-ray absorptiometry was used to analyze bone mineral content and lean tissue mass in the surgical and nonsurgical legs (n=14) at 0, 2, 4, and 8 weeks, and to evaluate bone mineral content and bone mineral density (BMD) of the proximal, mid-, and distal tibia of both the surgical and nonsurgical legs (n=15) at 0, 5, and 10 weeks. There was significant loss of bone mineral content and lean tissue in the surgical leg compared to the nonsurgical leg. Significant loss in bone mineral content and BMD was detected in the tibia of the surgical leg and was most pronounced in the metaphyseal region.
Recurrence of Gastric Dilatation-Volvulus After Incisional Gastropexy in a Rottweiler
Authors: Hammel Scott P. , Novo Roberto E.
Published: September 2014

An adult, castrated male rottweiler with a history of gastric dilatation-volvulus (GDV), which was treated 4 months previously by surgical gastric resection and incisional gastropexy, had a recurrence of clinical signs. Abdominal exploratory surgery revealed a 180°-clockwise GDV, with a stretched adhesion at the original gastropexy site. The stomach was repositioned, and additional gastropexies were performed adjacent to the original gastropexy site and at the gastric fundus. The recurrence of GDV in this dog with an intact gastropexy suggested that a risk for volvulus remains after therapeutic incisional gastropexy.
Chromobacterium violaceum Infection in Two Dogs
Authors: Crosse Patricia A. , Soares Karen , Wheeler Jason L. , Cooke Kirsten L. , Adin Chris A. , O’Kelley Jeffrey J. , Levy Julie Kay
Published: September 2014

Chromobacterium violaceum is a saprophyte of soil and water in tropical and subtropical environments that is associated with rare but highly fatal infections in animals and humans. Systemic infection was diagnosed in two critically ill dogs from Florida. Fever was absent in both dogs. Both dogs were treated surgically and provided with intensive care, but only one survived. The identification of characteristic, violet-pigmented bacterial colonies on routine microbial cultures should alert microbiologists and clinicians to the likelihood of this dangerous pathogen. Because of the rapidly progressive nature of this infection, empirical antibiotic administration with fluoroquinolones should be employed pending susceptibility testing.
Use of Inhaled Medications to Treat Respiratory Diseases in Dogs and Cats
Authors: Padrid Philip
Published: September 2014

Noninfectious disorders of the respiratory tract, including laryngitis, tracheitis, bronchitis, and asthma are common problems in dogs and cats. Traditional therapies have often included corticosteroids and bronchodilators given by mouth or injection. Side effects of this form of treatment can be severe and can result in cessation of therapy. Inhaled corticosteroid drugs are not as absorbed into the systemic circulation, do not result in significant side effects, and are now the standard of care for dogs and cats with respiratory diseases that would otherwise be treated with systemic medications.
Surgical Revision of the Urethral Stoma Following Perineal Urethrostomy in 11 Cats: (1998–2004)
Authors: Phillips Heidi , Holt David E.
Published: September 2014

Eleven cats required urethral stoma revision because of urethral stricture following perineal urethrostomy. At surgery, eight cats had evidence of inadequate dissection to the bulbourethral glands, and three cats had evidence of urine extravasation into the subcutaneous tissues. Following revision of the stoma, long-term follow-up was obtained in nine cases. For eight cats, owners reported no complications after the revision. Failure to dissect beyond the bulbourethral glands and inadequate mucosa-to-skin apposition resulted in postoperative stricture formation. Stoma revisions were performed a median of 71 days following the initial perineal urethrostomy, indicating that long-term evaluation of cases is necessary.
Intestinal Choristoma in the Midcervical Region of a Dog
Authors: Bentley Adrienne M. , Goldschmidt Michael H. , Bennett R. Avery
Published: September 2014

A 5-year-old, neutered male, mixed-breed dog was evaluated for a fluctuant mass in the right midcervical region. The mass recurred following aspiration of its contents and after removal of the right sublingual and mandibular salivary glands. The lateral midcervical location of the mass and the serous nature of the fluid within the mass were inconsistent with a salivary mucocele. Excisional biopsy was curative and revealed an intestinal choristoma.
Fibrocartilaginous Embolic Myelopathy in Five Cats
Authors: Mikszewski Jessica S. , Van Winkle Thomas J. , Troxel Mark T.
Published: September 2014

Five cats had clinical signs, radiographic findings, and cerebrospinal fluid analyses consistent with fibrocartilaginous embolic myelopathy. All cats had an acute onset of nonpainful, asymmetrical spinal cord signs (paresis or paralysis of one or more limbs). Magnetic resonance imaging was performed in three cats. On T2-weighted images, an intramedullary lesion was revealed that was hyperintense to normal spinal cord gray matter. On T1-weighted images, the lesion was isointense. Three of the cats were euthanized, and postmortem examination confirmed myelomalacia with intralesional fibrocartilaginous emboli. Two cats survived and were clinically improved within 3 weeks.
Severe Cholestatic Liver Disease Secondary to Liver Fluke (Platynosomum concinnum) Infection in Three Cats
Authors: Haney Davida Rachel , Christiansen Jeffrey S. , Toll Jeffrey
Published: September 2014

Three middle-aged domestic cats were presented for vomiting, lethargy, anorexia, and jaundice. Complete blood counts, serum biochemical profiles, and abdominal ultrasounds were suggestive of extrahepatic biliary obstruction in all of the cats. Infection with the liver fluke Platynosomum concinnum was confirmed by intraoperative bile cytology in three cases and by histopathology in two cases. All three cats were euthanized in the postoperative period because of complications. These cases illustrate the severity of signs and complications that can occur with liver fluke infection in cats.
Stenotic Nasopharyngeal Dysgenesis in the Dachshund: Seven Cases (2002–2004)
Authors: Kirberger Robert M. , Steenkamp Gerhard , Spotswood Timothy C. , Boy Sonja C. , Miller David B. , van Zyl Malan
Published: September 2014

Medical records of seven dachshunds with congenital nasopharyngeal stenosis from abnormally thickened palatopharyngeal muscles were reviewed. The intrapharyngeal ostium in all cases consisted of only a narrow slit. Dogs were presented with various clinical signs—the most common being dyspnea, expiratory cheek puff, salivation, pharyngeal dysphagia, oral dysphagia (to a lesser extent), and macroglossia. Diagnostic procedures included direct pharyngeal inspection, pharyngeal and thoracic radiography, fluoroscopy, lingual ultrasonography, biopsies in two dogs, and a postmortem examination in one dog. Diagnoses were readily made with radiographs and visual examinations. Macroglossia was confirmed with transcutaneous ultrasonography or a transmandibular finger test.
A Combination of Oral Cabergoline and Double Cloprostenol Injections to Produce Third-Quarter Gestation Termination in the Bitch
Authors: Corrada Yanina , Rodríguez Raúl , Tortora Mariana , Arias Daniel , Gobello Cristina
Published: September 2014

To assess the efficacy and safety of a combined cabergoline and cloprostenol protocol to terminate third-quarter pregnancy, 22 pregnant bitches that ranged from 35 to 45 days after mating were randomly assigned to a treatment group (n=13) or to an untreated control group (n=9). The animals were monitored for 12 days, and pregnancy termination was confirmed by ultrasound examination. Twelve of the 13 treated bitches aborted within 9 days of the initiation of treatment (mean 4.6 days). Only mild side effects were observed. The control animals had normal gestational courses, as did the bitch that did not respond to the therapy. This combination of drugs appeared to be a practical, safe, and efficient abortifacient when used in third-quarter pregnancies.
Subtotal Ear Canal Ablation in 18 Dogs and One Cat With Minimal Distal Ear Canal Pathology
Authors: Mathews Kyle G. , Hardie Elizabeth M. , Murphy K. Marcia
Published: September 2014

A modified technique for performing total ear canal ablations is described. This technique requires less dissection than the standard technique and maintains a portion of the distal vertical ear canal. Subtotal ear canal ablations were performed in 18 dogs and one cat for the treatment of otitis externa or masses of the horizontal ear canal. Animals with otitis externa had minimal involvement of the distal ear canal. Dermatological problems associated with the remaining ear canal and pinnae occurred in eight animals and resolved with medical management. Normal ear carriage was maintained in all animals with erect ears. Further investigation is required before the procedure can be recommended as a treatment for otitis externa not caused by masses or anatomical abnormalities of the horizontal ear canal in dogs with pendulous ears.
Left Lateral and Left Middle Liver Lobe Torsion in a Saint Bernard Puppy
Authors: von Pfeil Dirsko J.F. , Jutkowitz L. Ari , Hauptman Joe
Published: September 2014

A 5-month-old, male Saint Bernard was presented for acute collapse and abdominal discomfort. Significant findings were a cranial abdominal mass, hemorrhagic abdominal effusion, anemia, and disseminated intravascular coagulation. An exploratory surgery revealed torsion of both the left lateral and middle liver lobes, a condition that has not been previously described in the veterinary literature. Torsion of one or more hepatic lobes is a rare condition but should be considered as a differential diagnosis for acute abdomen syndrome in both young and mature dogs. Early diagnosis and prompt surgical intervention may be curative.
Ectopic Ureterocele in a Male Dog: A Case Report and Review of Surgical Management
Authors: Tattersall James A. , Welsh Elizabeth
Published: September 2014

A 16-week-old, male border terrier was presented for urinary incontinence. Intravenous urography demonstrated a right-sided, extravesical ectopic ureterocele. Neoureterocystostomy and ureterocele omentalization were performed. Urinary incontinence persisted after surgery. Retrograde urethrography revealed communication between the ureterocele and urethra. Urinary incontinence resolved following partial ureterocelectomy and reconstruction of the proximal urethra.
Care and Use of Feeding Tubes in Dogs and Cats
Authors: Wortinger Ann
Published: September 2014

Feeding tubes are an accepted way of providing nutritional support for animals unable or unwilling to consume adequate calories on their own. This article provides information on the indications for the use of feeding tubes in small animals, the types of tubes available, and ways to initiate nutritional support once the tubes are in place. The pros and cons of the various tubes are discussed, as well as potential complications.
Iatrogenic Hyperadrenocorticism in 12 Cats
Authors: Lien Yu-Hsin , Huang Hui-Pi , Chang Pen-Heng
Published: September 2014

Iatrogenic hyperadrenocorticism is an extremely rare condition in cats. Twelve cats with a medical history of progressive skin lesions and long-term treatment with corticosteroids were retrospectively studied. Noncutaneous signs in the cats were variable and included anorexia, lethargy, polydipsia, polyuria, and atrophy of the thigh muscles. Laboratory abnormalities included leukocytosis, elevated alanine aminotransferase levels, and hyperglycemia. Transient diabetes mellitus was a secondary complication in four cats, and transient hypothyroidism was suspected in four cats. The mean time for regression of signs was 4.9 months after corticosteroid withdrawal.
Noninvasive Correction of a Fractured Endoluminal Nitinol Tracheal Stent in a Dog
Authors: Ouellet Mathieu , Dunn Marilyn E. , Lussier Bertrand , Chailleux Nadège , Hélie Pierre
Published: September 2014

An 11-year-old, castrated male Pomeranian was presented for intractable cough and dyspnea secondary to severe tracheal collapse. An endoluminal nitinol tracheal stent was placed with good results. Five months following placement of the prosthesis, clinical signs acutely recurred and failure of the implant was noted. A second stent was superimposed over the fractured stent and resulted in resolution of all clinical signs. The dog died several months later from progression of the tracheal collapse to the carina and mainstem bronchi.
Effects of Diazepam or Lidocaine Premedication on Propofol Induction and Cardiovascular Parameters in Dogs
Authors: Braun Christina , Hofmeister Erik H. , Lockwood Abigail A. , Parfitt Shannon L.
Published: September 2014

The effects of diazepam or lidocaine on the propofol induction dose and certain cardiovascular parameters were documented in this randomized, blinded study. Dogs received 0.9% saline (0.1 mL/kg intravenously [IV]), lidocaine (2 mg/kg IV), or diazepam (0.25 mg/kg IV) prior to propofol IV until loss of jaw tone was achieved (up to a maximum of 8 mg/kg). Propofol was followed by 0.3 mg/kg atracurium IV. Direct arterial blood pressures and heart rates were recorded before premedication, induction, and intubation. No statistically significant differences were found among the groups for cardiovascular measurements or for the propofol dose required for intubation.
Phase II Clinical Trial of Combination Chemotherapy With Dexamethasone for Lymphoma in Dogs
Authors: Greenberg Chelsea B. , Boria Pedro A. , Borgatti-Jeffreys Antonella , Raskin Rose E. , Lucroy Michael D.
Published: September 2014

Dogs with histologically confirmed lymphoma were treated with a 14-week induction chemotherapy protocol that included dexamethasone. A phase II clinical trial was done using a standard two-stage design. Complete remission occurred in 21 (88%) dogs, with a median initial progression-free interval of 186 days. Toxicity was mild and self-limiting in the majority of dogs.
A Histopathological Comparison of Two Techniques for Soft Palate Resection in Normal Dogs
Authors: Brdecka David , Rawlings Clarence , Howerth Elizabeth , Cornell Karen , Stiffler Kevin
Published: September 2014

Eighteen dogs were used to compare histopathological findings following excision of the soft palate using either a bipolar sealing device or a carbon dioxide laser. Histopathological comparisons were done at 48 and 96 hours after soft palate resection. Mean depths of tissue injury at 96 hours were 3.5 and 3.33 mm for bipolar sealing device and carbon dioxide laser, respectively. Control of hemorrhage was excellent in all dogs, and none of the dogs developed signs of respiratory compromise after soft palate resection. Using the bipolar sealing device for soft palate resection was significantly faster than using the carbon dioxide laser, although both techniques were fast.
Parotid Duct Sialolithiasis in a Dog
Authors: Trumpatori Brian J. , Geissler Kyleigh , Mathews Kyle G.
Published: September 2014

Computed tomography was used to evaluate a 7-year-old English bulldog with a history of facial swelling and to aid in the diagnosis of parotid duct sialolithiasis. Removal of the sialolith with repair of the duct was not possible because of ductal fibrosis. Histological evaluation revealed glandular atrophy and fibrosis with lymphoplasmacytic inflammation. The parotid duct was ulcerated and fibrotic, with a mixed inflammatory infiltrate. Surgical excision of the parotid duct and salivary gland was curative.
Ultrasonographic Visualization of the Adrenal Glands of Healthy Ferrets and Ferrets With Hyperadrenocorticism
Authors: Kuijten Andrea Maria , Schoemaker Nico J. , Voorhout George
Published: September 2014

A protocol was developed to compare the ultrasonographic characteristics of the adrenal glands of 21 healthy ferrets and 37 ferrets with hyperadrenocorticism. By using specific landmarks, the adrenal glands were imaged in 97% of the cases. The adrenal glands of ferrets with hyperadrenocorticism had a significantly increased thickness, with changes in shape, structure, and echogenicity compared to the adrenal glands of healthy ferrets. Based on the findings of the study, adrenal glands may be classified as abnormal when they have a rounded appearance, increased size of the cranial/caudal pole (thickness >3.9 mm), a heterogeneous structure, increased echogenicity, and/or signs of mineralization.
Reevaluation of the University of Wisconsin 2-Year Protocol for Treating Canine Lymphosarcoma
Authors: Kaiser Claire Inderbinen , Fidel Janean L. , Roos Malgorzata , Kaser-Hotz Barbara
Published: September 2014

This retrospective study investigated a population of 96 dogs with newly diagnosed malignant lymphosarcoma that were treated with the commonly used University of Wisconsin-Madison (UW-M) chemotherapy protocol. Pretreatment characteristics were analyzed to determine prognostic factors. Dogs with higher World Health Organization (WHO) stages (including stage IV) and dogs with hypercalcemia were at significantly higher risk of relapse (P=0.018 and P=0.016, respectively). Dose reduction, treatment delays, and prior therapy with cortico-steroids were not associated with clinical outcome. First remission duration of 270 days was similar to historically reported data. Overall survival time of 218 days was much shorter than historical data.
Tibial Plateau Symmetry and the Effect of Osteophytosis on Tibial Plateau Angle Measurements
Authors: Ritter Matthew John , Perry Ruby L. , Olivier N. Bari , Kim Sun Young , Dejardin Loic M.
Published: September 2014

A novel technique was developed to estimate the caudal medial tibial plateau landmark in the face of osteophytosis to improve accuracy in tibial plateau angle measurements. Using this technique, tibial plateau angles were evaluated in 31 normal dogs before and 8 months after right cranial cruciate ligament transection. There was no significant difference in mean tibial plateau angle before or after induction of osteophytosis. Additionally, it was determined that 90% of dogs had a difference of =2° between right and left tibial plateau angles, which was considered symmetrical.
Ultrasound-Assisted Drainage and Alcoholization of Hepatic and Renal Cysts: 22 Cases
Authors: Zatelli Andrea , D’Ippolito Paola , Bonfanti Ugo , Zini Eric
Published: September 2014

Twenty-two dogs and cats with symptomatic renal or hepatic cysts that had undergone ultrasound-assisted drainage and alcoholization were retrospectively evaluated. Common presenting complaints were anorexia, reluctance to move, and vomiting. Abdominal pain was observed in all cases. Systemic hypertension was identified in four dogs and four cats with renal cysts. Cyst drainage and alcoholization were achieved without complications in 19 animals, and all clinical signs resolved after the procedure. In three cases, transient bleeding was observed during alcoholization, and the procedure was interrupted. Blood pressure normalized in the four dogs with renal cysts, but it remained elevated in the four cats.
Treatment of Feline Hypertension With Transdermal Amlodipine: A Pilot Study
Authors: Helms Scott Roderick
Published: September 2014

This prospective study evaluated transdermal amlodipine for the control of hypertension in six cats. Cats were treated with oral amlodipine until blood pressures decreased to <180 mm Hg. They were maintained on this dose for 7 days and then administered identical doses of transdermal amlodipine for 7 days. Oral amlodipine decreased pressure by a median of 73 mm Hg, which subsequently increased by 20 mm Hg after 7 days of transdermal amlodipine. Plasma concentrations of amlodipine were measured after oral and transdermal dosing. Additional studies are needed to determine dosing, pharmacokinetics, and efficacy.
Mucinous Cholangiocarcinoma in a Cat
Authors: Jacobs Terry M. , Snyder Paul W.
Published: September 2014

Mucinous cholangiocarcinoma was diagnosed in a 14-year-old, castrated male, domestic shorthaired cat with marked peritoneal effusion. Cytological confirmation of malignancy by fluid analysis and fine-needle, ultrasound-guided aspiration of the liver was followed by histological examination of tissue samples obtained at surgery and necropsy. No observed response followed chemotherapy with doxorubicin and carboplatin. Electron microscopy and immunohistochemistry helped to further characterize this unusual tumor.
Effects of Palliative Radiation Therapy on Nonsplenic Hemangiosarcoma in Dogs
Authors: Hillers Kim R. , Lana Susan E. , Fuller Chana R. , LaRue Susan M.
Published: September 2014

Medical records for 20 dogs with histologically confirmed nonsplenic hemangiosarcomas treated with palliative radiation therapy were reviewed to evaluate factors influencing tumor response and survival time. The Kaplan-Meier median survival time of dogs that received palliative radiation therapy was 95 days (range 6 to 500 days). Subjective reduction in tumor size was seen in 14 dogs, with four complete responses. Tumor location was a significant univariate prognostic factor for survival, and dogs with retroperitoneal masses had longer survival times.
Multiple Meningiomas in Three Dogs
Authors: McDonnell John J. , Kalbko Kerrianne , Keating John H. , Sato Amy F. , Faissler Dominik
Published: September 2014

Three dogs with seizures were diagnosed with multiple intracranial meningiomas. Two of the three dogs were golden retrievers, and ages ranged from 9 to 11 years. Treatment consisted of surgery and radiation (n=2) or chemotherapy (n=1). In all three cases, the masses were two distinct tumors as determined by imaging, surgery, or necropsy. In two dogs, the meningiomas had the same histological pattern, while in one dog the histological subtypes were different.
Adrenalectomy and Caval Thrombectomy in a Cat With Primary Hyperaldosteronism
Authors: Rose Scott A. , Kyles Andrew E. , Labelle Philippe , Pypendop Bruno H. , Mattu Jas S. , Foreman Oded , Rodriguez Carlos O. , Nelson Richard W.
Published: September 2014

A 13-year-old, castrated male, domestic longhaired cat was diagnosed with primary hyperaldosteronism from an adrenal gland tumor and a thrombus in the caudal vena cava. Clinical signs included cervical ventriflexion, lethargy, weakness, inappetence, and diarrhea. Laboratory tests revealed hypokalemia, normonatremia, hyperglycemia, hypophosphatemia, and elevated creatine kinase activity. Hypokalemia worsened despite oral potassium supplementation. An adrenalectomy and caval thrombectomy were successfully performed utilizing deliberate hypothermia followed by progressive rewarming.
Incomplete Atrioventricular Canal Complicated by Cardiac Tamponade and Bidirectional Shunting in an Adult Dog
Authors: Ohad Dan G. , Baruch Shahar , Perl Samuel
Published: September 2014

An incomplete atrioventricular (AV) canal with bidirectional shunting and cardiac tamponade in a 6-year-old dog was initially diagnosed echocardiographically as a common atrium. The dog failed to respond to medical therapy and was euthanized. Upon necropsy, the defect was confirmed as an incomplete AV canal. A mechanism for the potential sequence of clinical events demonstrated in this dog is proposed.
Comparison of the Results of Abdominal Ultrasonography and Exploratory Laparotomy in the Dog and Cat
Authors: Pastore Gina E. , Lamb Christopher R. , Lipscomb Victoria
Published: September 2014

Results of preoperative ultrasonography and exploratory laparotomy were reviewed retrospectively in a series of 100 small animals to assess the agreement between ultrasonographic and surgical findings and to identify abdominal lesions likely to be missed by ultrasonography. Good agreement occurred between ultrasound reports and surgical reports in 64% of the animals, which supported the use of ultrasonography in potential surgical candidates. A major discrepancy was observed between the ultrasound report and surgical findings in 25% of the animals. Of the various types of pathology encountered in the study, gastrointestinal ulceration or perforation was the most likely lesion to be missed by ultrasonography.
Metastatic Pericardial Tumors in a Dog With Equivocal Pericardial Cytological Findings
Authors: Guglielmini Carlo , Civitella Carla , Malatesta Daniela , Palmieri Chiara
Published: September 2014

A metastatic tumor associated with pericardial effusion was diagnosed in a 6-year-old, female, mixed-breed dog. Echocardiography identified multiple echogenic masses adherent to both visceral and parietal pericardium, while results of pericardial fluid cytology were non-diagnostic. The distribution pattern of the masses is remarkable in that they protruded from both pericardial surfaces, rather than one, and demonstrated an oscillatory motion during the cardiac cycle. Pathological examination confirmed the diagnosis of multiple metastatic tumors of the pericardium, with the primary tumor being an anaplastic gastric adenocarcinoma.
Reconstruction of a Nonhealing Lick Granuloma in a Dog Using a Phalangeal Fillet Technique
Authors: Demetriou Jackie L. , Shales Christopher J. , Hamilton Michael H. , Sissener Thomas R.
Published: September 2014

A 6.5-year-old, castrated male Dalmatian was presented with a 3-month history of a chronic, nonhealing wound related to a previously excised lick granuloma. Reconstruction of the wound on the lateral metatarsal region was achieved using a phalangeal fillet technique, without digital pad transposition. The skin flap healed successfully with very good cosmetic and functional results.
Administering Dental Nerve Blocks
Authors: Reuss-Lamky Heidi
Published: September 2014

Dental nerve blocks provide excellent pain management for many oral procedures. They are easy and inexpensive to perform, provide a rapid onset of action, and work in concert with anesthetic and other analgesic modalities. This article explains how to administer various dental nerve blocks and discusses the indications and precautions associated with their use.
Antimicrobial Testing of Selected Fluoroquinolones Against Pseudomonas aeruginosa Isolated From Canine Otitis
Authors: McKay Lindsay , Rose Crystal D. Schuman , Matousek Jennifer L. , Schmeitzel Lynn S. , Gibson Nicole M. , Gaskin Jack M.
Published: September 2014

A total of 100 Pseudomonas aeruginosa (P. aeruginosa) isolates were collected over a 1.5- year period from cases of canine otitis. Sensitivities to enrofloxacin, marbofloxacin, and orbifloxacin were determined using minimum inhibitory concentration testing (MICT). Isolates were also tested for sensitivities to enrofloxacin and marbofloxacin using disk-diffusion susceptibility testing (DDST). Isolates were significantly more sensitive to marbofloxacin than to enrofloxacin (z = −4.57; P<0.05) or orbifloxacin (z = −5.02; P<0.05). Agreement was 87% between MICT and DDST for marbofloxacin, with approximately equal numbers of overestimation and underestimation errors. Agreement was 74% between MICT and DDST for enrofloxacin, but DDST tended to overestimate the number of enrofloxacin-susceptible strains. These results suggest that marbofloxacin is more effective against P. aeruginosa than either enrofloxacin or orbifloxacin and that relying on DDST may lead to ineffective enrofloxacin treatment.
Susceptibility of Pseudomonas Isolates From the Ears and Skin of Dogs to Enrofloxacin, Marbofloxacin, and Ciprofloxacin
Authors: Wildermuth Brett Everett , Griffin Craig E. , Rosenkrantz Wayne S. , Boord Mona J.
Published: September 2014

The purpose of this study was to compare susceptibilities of ear and skin Pseudomonas spp. isolates to enrofloxacin, marbofloxacin, and ciprofloxacin. Specimens were obtained from dogs examined in a veterinary dermatology referral hospital. Susceptibilities of ear isolates to enrofloxacin, marbofloxacin, and ciprofloxacin were 46.9%, 66.7%, and 75.0%, respectively. Susceptibilities of skin isolates to the same drugs were 76.2%, 81.0%, and 80.0%, respectively. Ear isolates were significantly less susceptible to enrofloxacin than to ciprofloxacin (P=0.021), and ear isolates were significantly less susceptible to enrofloxacin than were skin isolates (P=0.034). When fluoroquinolone resistance was present, ear isolates were significantly less susceptible to enrofloxacin than to ciprofloxacin (P<0.001) and marbofloxacin (P=0.014).
Chronic Vaginitis Associated With Vaginal Foreign Bodies in a Cat
Authors: Nicastro Andrea , Walshaw Richard
Published: September 2014

A 2-year-old, spayed female, domestic shorthaired cat was presented for evaluation of a chronic, purulent vulvar discharge. Survey radiographs of the abdomen and pelvis revealed bone fragments in the pelvic canal. A vaginoscopy was performed, and five bony foreign bodies were removed from the vaginal lumen. Using anatomical landmarks, the bones were identified as remnants of a fetal kitten.
Aerobic Bacterial Culture of Used Intravenous Fluid Bags Intended for Use as Urine Collection Reservoirs
Authors: Barrett Masuma , Campbell Vicki L.
Published: September 2014

Numerous studies have shown a relationship between indwelling urinary catheters and bacterial urinary tract infection. Some veterinary hospitals utilize stored, used intravenous (IV) fluid bags as part of the urine collection system. The authors cultured 95 such bags to see if they were potential sources of bacterial contamination. Forty-two unused IV bags were emptied of their contents for use as controls. Results indicated no aerobic bacterial growth in either group. The authors conclude that properly stored, used IV bags are unlikely sources of aerobic bacterial contamination when used in a urine collection system.
Disease Association and Clinical Assessment of Feline Pericardial Effusion
Authors: Davidson Benjamin J. , Paling Anna C. , Lahmers Sunshine L. , Nelson O. Lynne
Published: September 2014

Records were reviewed from 83 cases to determine the main causes and clinical significance of feline pericardial effusion. The most common causes included hypertrophic cardiomyopathy with congestive heart failure, neoplasia, and systemic infection. Most cases had concurrent or secondary pleural effusion or pulmonary edema, with clinical signs of respiratory disease. However, several cases appeared to be affected solely by pericardial effusion rather than pulmonary pathology. Feline pericardial effusion remains an infrequent diagnosis, but its clinical relevance and association with severe cardiac and extracardiac disease warrant diagnostic evaluation.
Spontaneous Reduction of Intestinal Intussusception in Five Young Dogs
Authors: Patsikas Michail N. , Papazoglou Lyssimachos G. , Adamama-Moraitou Katerina K.
Published: September 2014

Five, 3- to 8-month-old dogs had clinical and ultrasonographic findings consistent with intestinal intussusception, but findings were negative on exploratory celiotomy. Ultrasonography had revealed a target-like mass (median maximal diameter 25 mm) on transverse section and multiple hyperechoic or hypoechoic parallel lines (median length 36.8 mm) on longitudinal section. Blood flow in the intussuscepted bowel was detected in most of the cases. In dogs with similar findings, the authors recommend ultrasonographic reexamination of the abdomen after general anesthesia (but before surgery) to exclude spontaneous reduction of the intussusception.
Long-term Survival of Dogs After Cholecystoenterostomy: A Retrospective Study of 15 Cases (1981–2005)
Authors: Papazoglou Lysimachos G. , Mann F.A. , Wagner-Mann Colette , Song Kug Ju Eddie
Published: September 2014

Fifteen dogs with extrahepatic biliary tract disease underwent cholecystoenterostomy. Long-term survivors were significantly older at presentation (mean age 140.5 months) than dogs that survived the first 20 days after surgery but subsequently died from causes related to the surgery or hepatobiliary disease (mean age 72 months). Dogs that died during the first 20 days had significantly more complications in the hospital than dogs that survived this period. The type of underlying hepatobiliary disease (i.e., benign or malignant) was not associated with either short-term outcome or long-term survival. Eight dogs died from causes related to surgery or hepatobiliary disease. Long-term complications included hepatic abscesses, acquired portosystemic shunts, pancreatitis, and vomiting.
Technique and Outcome of Nares Amputation (Trader’s Technique) in Immature Shih Tzus
Authors: Huck Jennifer L. , Stanley Bryden J. , Hauptman Joseph G.
Published: September 2014

Dogs with brachycephalic conformation frequently suffer from stenotic nares. This study investigated the clinical effects of stenotic nares resection in shih tzu puppies using an amputation technique first described in 1949. The authors hypothesized that surgical correction of the stenotic nares would result in improvement of nasal discharge/noise, breathing difficulty (dyspnea), and exercise limitations (exercise intolerance), and that the technique would provide a cosmetic result. Based on the results of this study, the authors recommend early surgical correction (amputation) of stenotic nares in shih tzu puppies as an effective and cosmetic technique.
Lumbosacral Intervertebral Disk Disease in Six Cats
Authors: Harris Jennipher E. , Dhupa Sarit
Published: September 2014

Medical records of six cats diagnosed with lumbosacral intervertebral disk disease were reviewed. Clinical signs included reluctance to jump, low tail carriage, elimination outside the litter box, reluctance to ambulate, pelvic-limb paresis, urinary incontinence, and constipation. All cats had lumbosacral hyperpathia on palpation. Computed tomography in four cats revealed evidence of extradural spinal cord compression at the seventh lumbar (L7) to first sacral (S1) vertebral interspace. Compression was confirmed via myelography in three of these four cats, with confirmation in the fourth cat at the time of decompressive laminectomy. Each of the six cats underwent dorsal decompressive laminectomy at the L7 to S1 interspace. Postoperative clinical follow-up lasted 3 to 35 months, with most cats having excellent outcomes.
Utility of Serum Cystatin C as a Clinical Measure of Renal Function in Dogs
Authors: Wehner Astrid , Hartmann Katrin , Hirschberger Johannes
Published: September 2014

A human kit for cystatin C determination was evaluated for use with canine sera. A reference range was also established. The association between cystatin C and glomerular filtration rate (GFR) was evaluated in 60 dogs with various diseases, by using exogenous creatinine plasma clearance (ECPC) as a measure of GFR. The correlation between cystatin C and ECPC (correlation coefficient [r] = −0.630; P<0.001) was stronger than the correlation between serum creatinine and ECPC (r = −0.572; P<0.001). Nonrenal diseases (e.g., neoplasia, infection) did not influence serum cystatin C concentration. Test sensitivity was significantly better (P<0.001) for cystatin C (76%) than for creatinine (65%). Specificities for the two tests were 87% and 91%, respectively.
Primary Tracheal Collapse in a Cat
Authors: Mims Holly L. , Hancock Robert B. , Leib Michael S. , Waldron Don R.
Published: September 2014

A 7-year-old, neutered male, domestic shorthair cat was presented for severe inspiratory dyspnea of 2 to 3 days’ duration. Radiography and tracheobronchoscopy confirmed the diagnosis of primary extrathoracic tracheal collapse. The cat was treated with oxygen, dexamethasone, and terbutaline, but no improvement was seen. Surgical correction was performed using nine prosthetic tracheal ring implants. Clinical signs improved after surgery, and the cat continued to do well 11 months after surgery, despite development of unilateral laryngeal paralysis.
A Review of Lameness Attributable to the Shoulder in the Dog: Part Two
Authors: Kunkel Kevin A. , Rochat Mark C.
Published: September 2014

The scapulohumeral joint is a common site of forelimb lameness in the dog. Establishing a definitive diagnosis may be difficult because of the limitations of orthopedic examination and radiographs and the inherent elusiveness of the associated conditions.

The intent of this review is to present, in a single reference, the pathophysiology, diagnosis, and treatment of reported causes of lameness intrinsically associated with the shoulder. Part One of this series discusses conditions associated with cartilage and bone maturation disorders and joint instability, while Part Two reviews tendon diseases, muscle disorders, synovial diseases, and soft-tissue mineralization disorders.
Management of Humeral and Femoral Fractures in Dogs and Cats With Linear- Circular Hybrid External Skeletal Fixators
Authors: Kirkby Kristin A. , Lewis Daniel D. , Lafuente M. Pilar , Radasch Robert M. , Fitzpatrick Noel , Farese James P. , Wheeler Jason L. , Hernandez Jorge A.
Published: September 2014

Linear-circular hybrid fixators were used to stabilize humeral and femoral fractures in 21 dogs and five cats. Twenty-two of 24 fractures with sufficient follow-up radiographic evaluation obtained union. Time to radiographic union ranged from 25 to 280 days (mean ± standard deviation [SD] 110±69 days; median 98 days). Eleven animals developed minor and two dogs developed major pin and/or wire tract inflammation. Functional outcome was rated as excellent (n=16), good (n=5), and fair (n=3) at the time of final long-term assessment (range 4.5 to 60.0 months; mean ± SD 28.4±15.4 months; median 28.5 months). Follow-up information was unavailable for two animals. Hybrid fixators were useful constructs for stabilization of humeral and femoral fractures, particularly fractures with short, juxta-articular fracture segments.
Granulocytopenia Associated With Thymoma in a Domestic Shorthaired Cat
Authors: Fidel Janean L. , Pargass Indira S. , Dark Michael J. , Holmes Shannon P.
Published: September 2014

A 5-year-old, spayed female cat was referred because of a mass in the cranial mediastinum noted on thoracic radiographs. A thymoma was diagnosed following ultrasound and biopsy of the mass. Treatment was initiated with coarse-fraction radiation therapy using external-beam therapy (four fractions of 5 Gy). The mass responded, but granulocytopenia developed. Bone marrow examination showed a myeloid to erythroid ratio of approximately 1:1, with a left shift within the myeloid line. These findings, as well as the lack of toxic changes within the peripheral blood neutrophils, suggested immune-mediated destruction of peripheral granulocytes. Immune suppression with prednisone and cyclosporine was instituted. After 7 weeks, the neutrophil count returned to normal. The tumor was removed, and cyclosporine was reduced and eventually discontinued 3 weeks postsurgery.
Surgical Treatment of an Elbow Hygroma Utilizing Microvascular Free Muscle Transfer in a Newfoundland
Authors: Green Michael L. , Miller Jonathan M. , Lanz Otto I.
Published: September 2014

Microvascular free muscle transfer utilizing the rectus abdominis muscle, in combination with a mesh skin graft and transarticular external fixator, were used following the surgical excision of an elbow hygroma in a Newfoundland dog. Postoperatively, the dog did well with minimal complications and has yet to have a recurrence 10 months following surgery. This report describes the utility and successful use of the rectus abdominis free tissue transfer in the surgical correction of a difficult elbow hygroma in the dog.
Coccidioidomycosis in Dogs and Cats: A Review
Authors: Graupmann-Kuzma Angela , Valentine Beth A. , Shubitz Lisa F. , Dial Sharon M. , Watrous Barbara , Tornquist Susan J.
Published: September 2014

The dimorphic fungi Coccidioides immitis and Coccidioides posadasii are the causative agents of coccidioidomycosis. Dogs and cats residing in and visiting endemic areas are at risk of exposure to infectious arthrospores. The primary infection is pulmonary and frequently results in chronic cough. Disseminated disease is common and causes cutaneous, osseous, cardiac, ocular, nervous system, or other organ disease. Radiographic changes include a variable degree of interstitial pulmonary infiltration, hilar lymphadenopathy, and osseous lesions. Serological titers support the diagnosis, but definitive diagnosis relies on identification of Coccidioides in cytological or tissue samples. Coccidioidomycosis should be considered in any dog or cat that has been potentially exposed during the previous 3 years and is presented with chronic illness, respiratory signs, lameness, lymphadenopathy, nonhealing cutaneous lesions, or neurological, ocular, or cardiac abnormalities.
Nasopharyngeal Turbinates in Brachycephalic Dogs and Cats
Authors: Ginn Jennifer A. , Kumar M.S.A. , McKiernan Brendan C. , Powers Barbara E.
Published: September 2014

This retrospective study reports the presence and incidence of nasal turbinates in the nasopharynx (nasopharyngeal turbinates) in a population of brachycephalic dogs and cats exhibiting signs of upper respiratory disease. Medical records were reviewed for 53 brachycephalic dogs and 10 brachycephalic cats undergoing upper airway endoscopy. Nasopharyngeal turbinates were identified in 21% of brachycephalic animals, including 21% of dogs and 20% of cats. Pugs accounted for 32% of all dogs in the study population and 82% of dogs with nasopharyngeal turbinates. The presence of nasopharyngeal turbinates may play a role in upper airway obstruction in the brachycephalic airway syndrome.
Primary Immune-mediated Thrombocytopenia in 30 Dogs (1997–2003)
Authors: Putsche Jutta C. , Kohn Barbara
Published: September 2014

During a 6-year period, primary (idiopathic) immune-mediated thrombocytopenia was retrospectively evaluated in 30 dogs. Ages of the dogs ranged from 3 months to 10 years (median 4 years); female dogs were markedly overrepresented with 73%. Clinical examination revealed hemorrhages in 70% of the dogs. Platelet counts ranged from 0 to 111,000/μL (median 8000/μL); 77% of the dogs had platelet counts <30,000/μL. Seventeen dogs were anemic (hematocrit 9% to 36%; median 31%). Immunosuppressive therapy was performed in all but one dog. The recurrence rate of 19 dogs that were followed over an extended period (112 to 1684 days; median 340 days) was 26%. Twenty-nine (97%) dogs survived 14 days after initial presentation, and 27 (93%) dogs survived at least the following 15 to 1684 days (median 220 days).
Delayed Primary Surgical Treatment in a Dog With a Persistent Right Aortic Arch
Authors: Loughin Catherine A. , Marino Dominic J.
Published: September 2014

A 5-year-old, 1.36-kg, neutered male Yorkshire terrier was referred for evaluation of a persistent right aortic arch with concurrent megaesophagus. The dog was 3 months old when clinical signs were first noted, 2 years of age when diagnosed with megaesophagus, and 4 years of age when diagnosed with vascular ring anomaly (VRA). Surgical correction of the VRA was performed when the dog was 5 years of age, after gastrostomy tube feeding for 1 year to maintain nutritional requirements and mitigate the degree and duration of the esophageal distention. Thirteen months after surgery, the dog was eating soft dog food with no vomiting or regurgitation.