bluuebunny/crossref_metadata_2025 huggingface dataset:
SOCIO CULTURAL PROFILE D0NGRIA KANDHA TRIBE OF ODISHA
Authors: Dr. Ashis Mohapatra
Published: October 2024

The Dongria Kandha, a section of the Kandha tribe of Odisha, live on the top of the Niyamgiris, a rugged mass of hill ranges situated on the borders of Rayagada and Gunupur sub-division of Rayagada district. In the case of the Dongria village the traditional panchayat is still effective and runs along democratic principles as before and serves the people well in the matters of maintaining social control and enforcing social sanctions. Every Dongria village had and still continues to have its own traditional council as part of the political organization. Considering the levels of economic development the Kandha tribe of Odisha are divided into several sub-sections such as- Kutia Kandha, Dongria Kandha, Jharia Kandha and Desia Kandha. Dongria section of the Kandha community. They are found in the Niyamgiri hill ranges, which comprise 3 Community Development blocks namely: Bissamcuttack, Kalyansingpur, Muniguda of Rayagada and Gunupur sub-division of Rayagada district.
1-D SEMICONDUCTING NANOWIRES AND THEIR ASSEMBLY
Authors: Selva Lakshman Murali
Published: October 2024

Nanowires, the one-dimensional(1D) semiconducting structures are one of the most potent and flexible classes of synthetically reconfigurable nanoscale basic elements widely used for examining the basic physical characteristics of nanomaterials and assembling a range of functional nanostructure systems. To design these functional nanostructure systems, it is critical to guarantee that the synthesis of these structures, as well as their assembly, are exceedingly exact and precise. The synthesis and assembly of these nanostructures is what defines the success of the nanostructure systems. Nanowire assembly is challenging because the required length scales prohibit direct interaction and increase the instability aspects of electrostatic forces and mass transfer. This paper focuses on the different core assembly methodologies of one-dimensional semiconductor nanowires into desired designs for functional nanostructure systems.
“IMPACT OF FAMILY ENVIRONMENT ON THE EDUCATIONAL INTEREST AMONG SECONDARY SCHOOL STUDENTS OF RAJASTHAN”
Authors: Dr. Vinod Kumar K. Satyapal  , Anju Pareek
Published: October 2024

A kid experiences a wide range of conditions from the moment of birth and continues to grow, gaining a wealth of knowledge in the process. This experience is what will teach him. John Locke asserted that humans develop via education and that plants grow via agriculture, acknowledging the significance of education in human existence. The foundation of a child's thinking and his mental development lies in his family, which is called his family environment. In today’s fast – paced and ever- changing world, high – quality education is becoming increasingly important. Student need to be trained not just for academic and professional success, but to be equipped with essential life skills and values needed to navigate through the various challenges  they may encounter in life. This is why human value education has become an important aspect of modern education. The impact of home environment on the scholastic interests of kids enrolled in private secondary schools in Rajasthan's Jaipur area has been investigated by the researcher.
This study used a survey approach to gather data from 200 children in the Jaipur  District , and the results showed that The analysis of the data obtained by the researcher proves that there is no significant difference in the family environment and educational interest of the secondary level students studying in the secondary schools of urban areas.
CLOUD ACCOUNTING UNVEILED: INVESTIGATING CHALLENGES AND PROSPECTS IN MODERN FINANCIAL MANAGEMENT
Authors: Dr. Rupam Mishra
Published: October 2024

Cloud accounting has emerged as a transformative force in modern financial management, offering businesses unprecedented opportunities to streamline processes, drive innovation, and achieve strategic objectives. This paper provides a comprehensive examination of cloud accounting, exploring its key features, benefits, challenges, and prospects in detail. The analysis begins by elucidating the fundamental concepts of cloud accounting, highlighting its accessibility, scalability, and cost efficiency compared to traditional accounting methods. It delves into the challenges faced by businesses in adopting cloud accounting, including security concerns, data privacy issues, integration complexities, and regulatory compliance requirements. Despite these challenges, the prospects for cloud accounting are bright, with numerous opportunities for businesses to leverage its benefits and drive growth. The paper identifies scalability, flexibility, cost efficiency, innovation, collaboration, security, and integration as key prospects in cloud accounting, highlighting their transformative potential in reshaping financial management practices. Furthermore, the paper underscores the importance of real-time collaboration, accessibility, and security in fostering a culture of transparency, accountability, and trust within organizations. It emphasizes the role of cloud accounting in creating interconnected ecosystems of applications and data sources, enabling better decision-making and operational efficiency across the organization.
URBANIZATION AND SOCIAL CRIME: A STUDY ON SOCIO-ECONOMIC DIMENSIONS OF THE MANIPUR CENTRAL VALLEY
Authors: Khwairakpam Shreeraj Singh  , Th. Nabakumar Singh
Published: October 2024

Geography is concerned to provide accurate, orderly, and rational description and interpretation of the earth's surface. The study of population dynamics and its impact on social crime is crucial for understanding regional development and planning. The present study examines the dynamics of population growth, urbanization, and social crime in Manipur's Central Valley. Utilizing, the data from the primary and secondary sources (such: NCRB, Superintendent of Police, Manipur central Valley, and Census of India). The research adopts technique, such as Decadal Growth method, Principal component Analysis. Over a 70-year period from 1951 to 2021, the region witnessed a consistent rise in population, growing from 3,87,523 to 18,77,416. Despite this growth, the pace has decelerated, reflecting a shift from high to moderate growth rates due to factors such as birth rates, mortality rates, and migration patterns. Urban population data from the 2011 Census reveals significant regional disparities, with Imphal West being the most urbanized and Bishnupur the least. Principal Component Analysis (PCA) of social crime data identifies three key patterns: "Anomie Violence," "Marginalized Deviance," and "Economic Strain Deviance," each associated with different regions and types of crime. A comparison of social crime patterns with urban population sizes highlights varying correlations, suggesting complex interactions between demographic changes and crime rates. This analysis underscores the need for targeted urban planning and crime prevention strategies in response to evolving socio-economic dimensions.
ASSESMENT OF ALIGNMENT OF EARLY CHILDHOOD CARE AND EDUCATION CENTRES WITH DEVELOPMENTALLY APPROPRIATE PRACTICE PRINCIPLES
Authors: Sandhya Rani Pal  , Dr. Sankar Prasad Mohanty
Published: October 2024

This study evaluates the alignment of 150 Anganwadi centres in Ganjam District, Odisha, with Developmentally Appropriate Practice (DAP) principles. Using an observation schedule, the research assesses infrastructure, resources, and teaching practices to identify challenges and opportunities in DAP implementation. Findings reveal significant infrastructure deficits, particularly the absence of dedicated buildings, which impede the creation of safe and stimulating learning environments. Despite these challenges, centres with adequate resources demonstrated effective DAP alignment, supported by strong parental and community involvement. The study underscores the need for continuous professional development for Anganwadi workers and policy reforms to increase funding and support for Early Childhood Care and Education (ECCE) programs. Cultural integration and tailored educational strategies emerge as essential for creating relevant and engaging learning experiences. The research concludes with recommendations to enhance DAP practices, aiming to improve holistic child development and educational outcomes in the region.
EFFECTS OF WARM, COOL, AND NEUTRAL COLORS ON SHORT TERM MEMORY IN YOUNG CHILDREN
Authors: Ms. Alvina Roy  , Ms. Jishi Thattil
Published: October 2024

This study investigates the impact of different color stimuli (neutral, warm, and cool) on short-term memory retention in children aged 9-10. A sample of 50 children was tested under varying color conditions, where participants viewed slides with different colored backgrounds (black for neutral, red for warm, and purple for cool) and recalled the words presented. The purpose of the research was to determine how these color conditions affect memory retention. Findings revealed that cool colors, particularly purple, significantly enhance memory retention more effectively than warm (red) and neutral (black) colors. These results suggest that incorporating cool colors into educational materials and environments can optimize learning by improving short-term memory retention. This study highlights the importance of considering environmental factors, such as color, in designing educational strategies and classroom settings to support cognitive development. The principal results indicate that specific color stimuli can positively influence cognitive functions in children, providing empirical insights for educators and curriculum developers. Major conclusions from this research include the potential benefits of using cool colors like purple in educational contexts to enhance memory performance and learning outcomes. Future research should explore the impact of various sensory stimuli on cognitive processes across different developmental stages to further refine educational practices. By understanding the relationship between color and memory, this study contributes to the development of targeted interventions aimed at improving cognitive performance and educational experiences for children.
A STUDY ON REPRODUCTIVE LIFE OF THE BENGALEE HINDU FEMALES: A COMPARATIVE ANALYSIS
Authors: Jayita Roy Tapadar
Published: October 2024

Reproduction is the process by which new individuals of a species are produced and the genetic materials are passed through generation after generation (Tortora, 2003). The existence of a species is maintained through the urge for the reproduction. Pearl (1939) accounted the urge for reproduction as basic attribute of all living organisms. The expressive form of this urge for the reproduction could be accounted as reproductivity or fertility. The urge for the reproduction in human could not be expressed in its full strength due to several restrictive factors work on it. Demographically observed fertility or infertility is the result of a well-defined number of both biological and behavioural factors, which serve to mediate the influence of culture, society, economic conditions, living standards, and other similar background determinants on individual reproductive behavior (Frank et al., 1994). The hedonistic attitude of human for the reduction of fertility would be described through the "Demographic Transition Model" (DTM) which defines the transition from high birth rates and high death rates to low birth rates and low death rates as part of the economic development of a country from a pre-industrial to an industrialized economy (Thompson, 1929). In the present study an attempt has been made to understand the current status of the reproductive life of the contemporary Bengalee females and the effect of demographic transition as well as fertility transition on the same. Materials of the present cross sectional study comprises with 200 adult married Bengalee females belonging to different caste group lived in a semi urban region of west Bengal. Mean age of the population was 32.63 ± 10.64. The result shows a remarkable decadal change in the reproductive life of the population. Age at menarche seems to follow the secular trend to being decreasing when comparing with a data (mean age 12.79 ± 41.37 and 13.41 ± 1.48 respectively). Comparison with a previous work revealed that the rate of literate women, employed women, the family income etc have been increased noticeable. The number of contraceptive used or adopt family planning families has also been increased remarkably in comparison with the earlier data (64.5 % and 56% respectively). Accordingly the rate of live birth has been decreased. The present study also differs from the age at marriage and marriage conception interval (MCI). Thus the present work revealed that the females (mothers) as well as the couples are more conscious about their reproductive life and adopt different family planning methods. Sharp decadal changes on their reproductive life could also be noticed which may be the ultimate result of the demographic transition.
EVALUATION OF PHYTOCHEMICALS, MOSQUITO LARVICIDAL AND ALLELOPATHIC POTENTIAL OF AGERATUM CONYZOIDES L.
Authors: Jyothy V J  , Ayisha Hiba
Published: October 2024

Ageratum conyzoides, commonly known as "Billygoat Weed" or "Whiteweed," is a medicinal plant with widespread distribution and recognized for its traditional uses. This study aims to investigate the allelopathic potential of A. conyzoides, assess its mosquito larvicidal activity, and conduct a preliminary phytochemical screening to identify bioactive compounds. The allelopathic impact will be evaluated through germination assays and seedling growth inhibition experiments, shedding light on the potential of A. conyzoides in natural weed control strategies. Simultaneously, the mosquito larvicidal activity will be examined by evaluating the efficacy of A. conyzoides extracts against mosquito larvae, contributing to the exploration of environmentally friendly mosquito control approaches. Preliminary phytochemical screening will involve the identification of primary and secondary metabolites present in A. conyzoides, providing a foundation for further isolation and characterization of potential pharmacologically active compounds. The comprehensive findings from this study will contribute to a better understanding of the multifaceted ecological roles of A. conyzoides and its potential applications in weed management and vector control.
EXPERIMENT TO DETECT THE ABSOLUTE VELOCITY OF EARTH IN THE UNIVERSE
Authors: Dharam Vir Singh
Published: October 2024

A number of experiments have been carried out to measure the velocity of earth in the space but absolute velocity of earth could not be detected. One of the most famous Michelson and Morley experiment was conducted in the year 1887 to detect the motion of earth with reference to luminiferous aether a supposed medium permeating space that was thought to be the carrier of light waves but unexpected results were obtained. The experiment has given negative results, MMX type experiments have been repeated so many times with steadily increasing sensitivity from 1902 to 1930 and more recently in the year 2009 by optical resonator but all the experiments confirmed the negative results of MMX. Albert Einstein submitted his special theory of relativity in the year 1905 and stated that there is no medium like aether for propagation of light waves and there is no absolute velocity in the universe, all the motions are relative. Relative velocity of earth has been measured by various methods and observations such as stellar parallax, position of stars and planets, satellite laser ranging, GPS and CMB radiation.
Second postulate of STR states that velocity of light is constant in all inertial frames of reference, there is no effect of motion of source of light or observer on the speed of light. As the velocity of light is a universal Constant hence any velocity with reference to speed of light will be absolute velocity. On the basis of second postulate of STR absolute velocity of earth in the universe can be determined by experiment based on the laser light beams. A laser beam may be directed on the fixed screen and movement of laser spot due to motion of earth may be observed. The displacement of laser spot with passage of time may be observed to determine the velocity of earth. In the present article it is explained how the velocity of earth may be detected by measuring displacement of laser spot. The displacement of laser spot from its normal position will determine the absolute velocity of earth in the universe.
METAMORPHOSIS: REACTIVATION IN DEVELOPMENT OF UNNAMED NARRATOR IN MARGARET ATWOOD'S SURFACING
Authors: Dr. Divya Verma
Published: October 2024

Margaret Atwood stands as a beacon of creative versatility in the realm of literature, boasting a distinguished and internationally renowned reputation. She holds a place among the most acclaimed authors of fiction in recent memory. Atwood's second published novel, "Surfacing," not only showcases her prowess in prose but also delves into thematic concerns reminiscent of her poetic works. In "Surfacing," Atwood masterfully crafts a narrative that follows a woman burdened by the toll of her past marital experiences. However, what sets this novel apart is the protagonist's transformative journey from a state of psychic and emotional paralysis to one of unified agency. This progression carries with it a potent mythic dimension, a depth that distinguishes it from her earlier works. Through evocative prose, Atwood paints a portrait of resilience and self-discovery that resonates profoundly with readers, cementing her status as a literary luminary.Top of Form Metamorphosis (Transformation) is widely used themes in literature and its situations are varied in different works. The cause for transformation is diverse and can be portrayed in numerous ways. The present research paper is present the role of Metamorphosis (transformation) in the context of Margaret Atwood’s Surfacing. The purpose of this research paper is to analyze the unnamed narrator’s the way of Metamorphosis. In 'Surfacing' the narrator undergoes both physical and psychological metamorphosis, navigating a complex terrain of self-discovery and identity. The return to her childhood home in the remote Canadian wilderness serves as a catalyst for her transformation, prompting a reconnection with her past and a confrontation with suppressed memories and emotions. This journey parallels an internal metamorphosis as she sheds societal expectations and embraces her true self. Additionally, the narrator’s interactions with the natural world play a crucial role in her transformation. Immersed in the wilderness, she becomes attuned to its rhythms, blurring the boundaries between herself and her environment. This fusion symbolizes a profound metamorphosis, as she transcends human constraints and embraces a more primal existence. ‘Surfacing’ offers a compelling exploration of Metamorphosis through the lens of the unnamed narrator's journey. Atwood's nuanced portrayal of transformation invites readers to reflect on their own experiences of identity and introspection, making 'Surfacing' a timeless and thought-provoking work of literature."
CYBER CRIME CYBERSTALKING THROUGH THE CYBER LAW FORENSIC SCIENCE AND CRIMINAL INVESTIGATION
Authors: Vyas Shivangi Anilkumar  , Dr. Prakashkumar Thakor
Published: October 2024

As it is well known, the usage of the internet and mobile phones has entirely turned this world into a virtual one. In this virtual setting, Pandemic 2020 offers a fresh viewpoint on human existence. IT now serves as a crucial organ for survival. Not only has information technology expanded the sphere of development, but it has also turned into an axis for global development. People may quickly and easily access a variety of information in the virtual world. However, everything has two sides, just like a coin, and the development of information technology has sped up the growth of cybercrime everywhere.
Cyber stalking is the act of following someone using a computer or other device connected to one, which can instil terror in the victim. A relatively modern form of cybercrime is cyber stalking.
The study focuses about the meaning, nature, typology and history of cyber stalking.. This thesis compares the law relating to cyber stalking in India with different foreign countries. This thesis also discussed about the reported cases of cyber stalking from 2017-2020 as per the data of NCRB. Reason and effect of cyber staling has also been discussed in this study. Scholar suggests that there is the need of amendment of current laws specifically for the gender neutral laws and law which add the issues of international jurisdiction. Study also suggest that self-awareness is also needed for safeguard ourselves from such crimes.
Digital technology is encompassing in all walks of life, all over the world and has brought the real meaning of globalization. At the one end cyber system provides opportunities to communicate and at the other end some individuals or community exploit its power for criminal purposes. Criminals exploit the Internet and other network communications which are international in scope.
Situation is alarming; Cybercrime is an upcoming and is talk of the town in every field of the society/system. Theoretically and practically this is a new subject for researchers and is growing exponentially. Lot of work has been done and endless has to be go because the invention or up gradation of new technology leads to the technical crime i.e. the digital or we can say the cybercrime or e-crime.
This is because every day a new technique is being developed for doing the cybercrime and many times, we are not having the proper investigating method/model/technique to tackle that newly cybercrime. Cybercrime is a criminal activity in which computers or computer networks are used as a tool, a target, or a place of criminal activity and includes everything from electronic cracking to denial of service attacks. It is also used to include traditional crimes in which computers or networks are used to enable the illicit activity.
UNDERSTANDING GROUNDWATER DEPLETION IN INDIA: ASSESSING RISK THRESHOLDS AND ANALYSING CAUSATIVE FACTORS
Authors: Vian Dhanda
Published: October 2024

Although hidden below the Earth’s surface, groundwater makes up 99% of Earth’s liquid fresh water and plays an important role in the water cycle. Rivers, lakes and wetlands are surface manifestations of groundwater, exchanging flow with the groundwater reservoir that feeds them when they need water and takes some of their flow when surface water is in excess. Groundwater also controls many features on the Earth’s surface. The depth of the water table is partly responsible for different plant species occupying different positions along the slopes from hill to valley, as only the drought-tolerant plants can live on dry hillsides and water-tolerant plants live near streams. Dissolution of carbonate rocks by flowing groundwater creates caves and sinkholes. In desert environments, groundwater discharge forms oases, which provide habitats for animals and plants. Groundwater provides drinking water entirely or in part for as much as 50% of the global population and accounts for 43% of all water used for irrigation. Worldwide, 2.5 billion people depend solely on groundwater resources to satisfy their basic daily water needs. The Earth’s population of nearly 8 billion in 2020 is expected to reach 11 billion by 2100. Humans will have to learn to produce sufficient food without destroying the soil, water and climate. This has been called the greatest challenge humanity has faced. Sustainable management of groundwater is at the heart of the solution. Scientific understanding and proper management of groundwater is essential because groundwater can alleviate the problem if we seek its responsible use and replenishment. Modern scientific measurements show that many of the major aquifers (groundwater reservoirs) of the world are being depleted. Such depletion can lead to a decrease in stream flow, drying of springs or wetlands, loss of vegetation, water-level declines in wells, and land subsidence. Yet another threat to groundwater is pollution resulting from human activity, generating chemicals and wastes that have leaked into the subsurface. Pollution degrades the quality of groundwater and poses a threat to human and ecological health. As the human population grows, more demand will be placed on groundwater, a vast, but finite, resource. The need for understanding our groundwater systems and thoughtfully managing them within the constraints of the hydrologic cycle is greater than ever. In this paper, our primary objective is to examine the history of the water crisis in India, critical risk tipping points and delve into the analysis of how we arrived at the current state of groundwater depletion, exploring the specific conditions and factors that have led us here. Furthermore, we will project the trajectory of this situation and assess where we are headed. Most importantly, we will outline the vision for the future that we aim to craft, considering the well-being of the next generations and the sustainability of India's groundwater resources.
OPTIMIZING INVENTORY MANAGEMENT: AMAZON’S STRATEGIES IN RURAL SUPPLY CHAINS
Authors: Arjun Budhiraja
Published: October 2024

The world's largest online retailer, Amazon, has invested heavily in infrastructure and technology to save costs and improve operations. Amazon has the most efficient supply chain in the world due to cutting-edge robotics and artificial intelligence (AI) technology that can improve productivity and worker safety. Amazon's regional distribution centers use advanced algorithms, route optimization technology, and mapping tools to effectively handle deliveries in rural areas. Artificial intelligence (AI) technologies, machine learning, and Amazon Prime membership are some initiatives that personalize recommendations and enhance the purchasing experience. To get around logistical challenges in rural locations, Amazon also collaborates with regional businesses and delivery services. To save expenses and wait times for last-mile deliveries in remote places, Amazon has made investments in micro-fulfillment centers to reduce last-mile delivery time and costs in rural areas.
COMMENTS ON THE EPIC: SHARANUBASAVA: THE SCION OF MAHADASOA
Authors: Dr. Chidambar Patil
Published: October 2024

COMMENTS ON THE EPIC: SHARANUBASAVA: THE SCION OF MAHADASOA
SKILLQUEST EDU: GAME-BASED EDUCATION FOR STUDENTS WITH DISABILITIES (DEAF)
Authors: Dr. Vijayalakshmi P.  , Vinish V.  , Santhosh Kumar B.  , Sunil Kumar A.  , Suryaprakash S.
Published: October 2024

Skill Quest Edu is an innovative platform empowering deaf individuals in mastering pronunciation and language skills with over 90% accuracy. In the current educational landscape, traditional approaches may not fully accommodate diverse learning needs, leading to limited resources and disparities. Our proposed system addresses these challenges by integrating game-based education, providing interactive learning experiences tailored to individual strengths and challenges. SkillQuest Edu aims to bridge communication barriers, fostering confidence and proficiency in language acquisition among deaf learners.
Integración de la tecnología y la pedagogía en los sistemas de tutoría inteligente
Authors: Ruiz Muñoz Geovanny Francisco
Published: October 2024

Los Sistemas de Tutoría Inteligente (STI) han demostrado su potencial para mejorar el proceso de enseñanza-aprendizaje al brindar instrucción personalizada y adaptativa. Sin embargo, la integración efectiva de la tecnología y la pedagogía en estos sistemas sigue siendo un desafío. Este estudio tuvo como objetivo analizar los enfoques y estrategias más efectivos para lograr esta integración. Se empleó una metodología mixta que combinó análisis bibliométricos, minería de textos, análisis de contenido y entrevistas a expertos. Los resultados destacan la importancia de utilizar modelos de estudiante precisos, incorporar enfoques constructivistas y de aprendizaje multimedia, aplicar retroalimentación adaptativa y andamiaje, y diseñar interfaces envolventes. También se identificaron desafíos relacionados con la accesibilidad, escalabilidad y consideraciones éticas. Se concluye que una combinación óptima de avances tecnológicos, principios pedagógicos sólidos y una comprensión profunda de las necesidades individuales de los estudiantes es crucial para el éxito de los STI.
Responsabilidad en salud y factores asociados en adultos de la Regional Norte de Santander, Colombia
Authors: Barajas-Lizarazo Mayra Alejandra , Carvajal-Suárez Lennys Soley
Published: October 2024

Introducción: los adultos son colectivos autónomos de las conductas que adoptan para asumir la responsabilidad sobre su salud. Sin embargo, diversos factores pueden influir en ese propósito. Objetivo: identificar las prácticas de responsabilidad en salud y los factores asociados en los adultos de la Regional Norte de Santander, Colombia. Método: se efectúo un estudio transversal, de correlación, en el que se incluyeron personas mediante un muestreo no probabilístico por conveniencia. Se utilizó un cuestionario estructurado respecto a la frecuencia con que asumen comportamientos de responsabilidad en salud y variables sociodemográficas. Resultados: participaron 547 adultos con edades comprendidas entre 18 a 84 años, en quienes se evidenció que sólo algunas veces, casi nunca o nunca, efectuaron las prácticas de responsabilidad en salud; se encontraron diferencias estadísticamente significativas con algunas de las características sociodemográficas evaluadas. Conclusiones: factores como el sexo, género, curso de vida, último nivel de escolaridad, la actividad laboral actual, y el régimen de afiliación al Sistema General de Seguridad Social en Salud, se relacionaron con las prácticas de responsabilidad en salud de los adultos de la regional de Norte de Santander Colombia participes de la investigación.
Probióticos para la prevención y tratamiento de la mucositis oral en quimioterapia y radioterapia: una meta-revisión
Authors: Plazas-Román Jaime , Guerrero-Román Mauricio , Gutiérrez-Ramírez Gennys , Torres-Osorio Lenin , Díaz-Caballero Antonio
Published: October 2024

Introducción: la mucositis oral es una complicación frecuente y dolorosa del tratamiento oncológico que afecta significativamente la calidad de vida de los pacientes. Objetivo: determinar la eficacia de los probióticos en la prevención y tratamiento de la mucositis oral en pacientes con cáncer sometidos a quimioterapia y/o radioterapia. Método: se realizó una meta-revisión siguiendo las directrices PRISMA. Se buscaron artículos publicados entre 2019 y 2024 en cuatro bases de datos. Resultados: los probióticos redujeron significativamente la incidencia de mucositis oral (RR = 0,84) y mucositis oral severa (RR = 0,65). Los probióticos multi-cepa fueron más efectivos que los de cepa única, con mayor eficacia observada en poblaciones asiáticas. Conclusiones: los probióticos son una estrategia prometedora para prevenir y tratar la mucositis oral en pacientes con cáncer, mostrando una reducción significativa en su incidencia y gravedad. Se necesitan más estudios para optimizar la selección de cepas, establecer dosis y duraciones óptimas, y entender los mecanismos de acción en diversas poblaciones y tipos de cáncer.
Factors associated with attitudes towards sexuality in Venezuelan migrants in Pamplona, Colombia
Authors: Escobar-Velásquez Katty Dayana , Barajas-Lizarazo Mayra Alejandra , Echávez José Luis , Rodríguez-Lizcano Claudia Milena
Published: October 2024

Introduction: Sexuality is an essential dimension in human beings. Migrants become a vulnerable population in situations that affect their sexual and reproductive rights. Objective: This study aimed to identify the factors associated with attitudes towards sexuality in Venezuelan migrants in Colombia. Method: A cross-sectional study was conducted with a sample of Venezuelan migrants over 18 years of age, selected at convenience. Sociodemographic characteristics were evaluated, and the Trueblood Sexual Attitudes Questionnaire (TSAQ) scale was applied, which evaluates attitudes towards one's sexuality (self) and others. Results: Participated 369 adults. The study group's average TASQ score was 5.81 ± 0.65. By subscale, the highest average occurred in homosexuality (8.39), followed by sexual variation (6.37), autoeroticism (4.93), commercial sex (4.70), and heterosexuality (4.27). Conclusions: Sociodemographic factors such as schooling, having children, occupation, level of study, social stratum, and sexual orientation influence attitudes toward sexuality in migrants.
Cuidado de enfermería a la persona adulta con fibromialgia: reporte de caso
Authors: Giraldo-Giraldo Yaison Dorney , Tejada-Pérez Indira Islem , Correa-López John Fredy
Published: October 2024

La fibromialgia es una enfermedad que causa dolor, rigidez y sensibilidad en músculos, tendones y articulaciones. Se presenta el caso de una mujer de 65 años con fibromialgia, el proceso de enfermería se elaboró con la teoría de los patrones funcionales de Marjory Gordon y las taxonomías NANDA, NIC y NOC. Se priorizó el deterioro de la movilidad física, insomnio y síndrome de dolor crónico. Se concluye que, debido al aumento de personas con fibromialgia, la demanda de atención y la inespecificidad de los síntomas, el cuidado a las personas con fibromialgia y sus familias constituye un reto para enfermería.
Día Mundial de la Salud Mental: “Es tiempo de priorizar la salud mental en el lugar de trabajo”
Authors: Herazo Edwin , Vargas-Betancourt Mónica Lorena , Campo-Arias Adalberto
Published: October 2024

La conmemoración del Día de la Salud Mental se enmarca en la estrategia de posicionar la salud mental en la agenda pública mundial mediante la promoción y la concientización. Esta conmemoración se inició en 1992 por iniciativa de la Federación Mundial de Salud Mental (FMSM), fundada en 1948 por sugerencia del entonces director general de la Organización Mundial de la Salud, psiquiatra canadiense George Brock Chisholm, como un organismo internacional no gubernamental que fortaleciera los lazos entre las organizaciones civiles de salud mental y las agencias de la Organización de las Naciones Unidas, como quiera que la FMSM, derivó del antiguo Comité Internacional de Higiene Mental que en 1919 constituyó el activista estadounidense Clifford Beers en la calidad de paciente de un hospital mental.
FORMY DZIAŁANIA ADMINISTRACJI NA CZAS KRYZYSU – UWAGI NA TLE ADMINISTROWANIA W CZASIE PANDEMII
Authors: Dąbek Dorota
Published: October 2024

Artykuł stanowi przyczynek do dyskusji nad dopuszczalnymi formami działania administracji i dopuszczalną granicą ingerencji administracji w wolność osobistą, polityczną i ekonomiczną jednostki w sytuacjach kryzysowych. Przedmiotem analizy są kontrowersyjne rozwiązania normatywne w zakresie form działania administracji obowiązujące w czasie pandemii COVID-19, w okresie od marca 2020 r. do czerwca 2023 r., zawartych w ustawie z 5 grudnia 2008 r. o zapobieganiu oraz zwalczaniu zakażeń i chorób zakaźnych u ludzi i wydanych na jej podstawie rozporządzeniach Rady Ministrów. Celem opracowania jest ocena tych regulacji i reﬂeksja nad pożądanym kierunkiem zmian dla stworzenia najbardziej optymalnych rozwiązań, będących kompromisem pomiędzy skutecznością działań – szczególnie potrzebną w kryzysowych sytuacjach – a ochroną podstawowych wartości i praw człowieka i obywatela.
POJMOWANIE ZASADY ‘SUPERFICIES SOLO CEDIT’ NA TLE KODEKSU CYWILNEGO
Authors: Kalisiak Damian
Published: October 2024

Asumptem do napisania artykułu była chęć przybliżenia czytelnikom regulacji prawnych obowiązujących w starożytnym Rzymie, a także przepisów kodeksu cywilnego wraz z orzecznictwem odnoszących się do nieruchomości i instytucji superficies. Celem niniejszej pracy jest przedstawienie pochodzenia rzymskiego prawa superficies. W artykule posłużono się metodą historyczną. Analiza poszczególnych przepisów aktów prawnych pozwala na określenie praw i obowiązków superficjusza i właściciela gruntu. W opracowaniu poruszono aktualne orzecznictwo dotyczące tego tematu. W artykule wskazano też istotne wyjątki od zasady superficies solo cedit, a także jak bardzo ważna jest obecnie.
SŁOWA TEGOŻ MESSALI DOWODZĄCEGO, ŻE CZYM INNYM JEST PRZEMAWIANIE DO LUDU, A CZYM INNYM ZWRACANIE SIĘ DO LUDU; ORAZ O TYM, KTÓRZY URZĘDNICY MOGĄ KTÓRYM ODBIĆ ZGROMADZENIE AULUS GELLIUS, ‘NOCE ATTYCKIE’ 13,16 TEKST – TŁUMACZENIE – KOMENTARZ
Authors: Tarwacka Anna
Published: October 2024

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Phenolic Glycoside Monomer from Reed Rhizome Inhibits Melanin Production via PI3K-Akt and Ras-Raf-MEK-ERK Pathways
Authors: Pang Meijun , Yao Hong , Bao Kechen , Xu Ruitian , Xi Rongjiao , Peng Rui , Zhi Hui , Zhang Kuo , He Runnan , Du Yunfei , Su Yanfang , Liu Xiuyun , Ming Dong
Published: October 2024

Introduction:

Melanogenesis, the process responsible for melanin production,
is a critical determinant of skin pigmentation. Dysregulation of this process can
lead to hyperpigmentation disorders.

Method:

In this study, we identified a novel Reed Rhizome extract, (1'S, 2'S)-syringyl
glycerol 3'-O-β-D-glucopyranoside (compound 5), and evaluated its anti-melanogenic
potential in zebrafish models and in vitro assays. Compound 5 inhibited melanin synthesis
by 36.66% ± 14.00% and tyrosinase in vivo by 48.26% ± 6.94%, surpassing the inhibitory
effects of arbutin. Network pharmacological analysis revealed key targets, including
HSP90AA1, HRAS, and PIK3R1, potentially involved in the anti-melanogenic
effects of compound 5.

Results:

Molecular docking studies supported the interactions between compound 5 and
these targets. Further, gene expression analysis in zebrafish indicated that compound 5
up-regulates hsp90aa1.1, hrasa, and pik3r1, and subsequently down-regulating mitfa,
tyr, and tyrp1, critical genes in melanogenesis.

Conclusion:

These findings suggest that compound 5 inhibits melanin production via
PI3K-Akt and Ras-Raf-MEK-ERK signaling pathways, positioning it as a promising candidate
for the treatment of hyperpigmentation.
Structural Prediction and Antigenic Analysis of ROP18, MIC4, and SAG1 Proteins to Improve Vaccine Design against Toxoplasma gondii: An In silico Approach
Authors: Nayeri Tooran , Sarvi Shahabeddin , Fasihi-Ramandi Mahdi , Asgarian-Omran Hossein , Ajami Abolghasem , Hosseininejad Zahra , Dodangeh Samira , Daryani Ahmad
Published: October 2024

Background:

Toxoplasmosis is a cosmopolitan infectious disease in warm-blooded mammals that poses a serious worldwide threat due to the lack of effective medications and vaccines.

Aims:

The purpose of this study was to design a multi-epitope vaccine using several bioinfor-matics approaches against the antigens of Toxoplasma gondii (T. gondii).

Methods:

Three proteins of T. gondii, including ROP18, MIC4, and SAG1, were analyzed to predict the most dominant B- and T-cell epitopes. Finally, we designed a chimeric immunogen RMS (ROP18, MIC4, and SAG1) using some domains of ROP18 (N377-E546), MIC4 (D302-G471), and SAG1 (T130-L299) linked by rigid linker A (EAAAK) A. Physicochemical prop-erties, secondary and tertiary structures, antigenicity, and allergenicity of RMS were predicted utilizing immunoinformatic tools and servers.

Results:

RMS protein had 545 amino acids with a molecular weight (MW) of 58,833.46 Da and a theoretical isoelectric point (IP) of 6.47. The secondary structure of RMS protein con-tained 21.28% alpha-helix, 24.59% extended strand, and 54.13% random coil. In addition, eval-uation of antigenicity and allergenicity showed the protein to be an immunogen and non-aller-gen. The results of the Ramachandran plot indicated that 76.4%, 12.9%, and 10.7% of amino acid residues were incorporated in the favored, allowed, and outlier regions, respectively. ΔG of the best-predicted mRNA secondary structure was −593.80 kcal/mol, which indicated that a stable loop was not formed at the 5′ end.

Conclusion:

Finally, the accuracy and precision of the in silico analysis must be confirmed by successful heterologous expression and experimental studies.
Hydroxylation of Phenol by an Azomethine Quinoxaline Schiff Base Copper (II) Complex
Authors: Arun Vasudevan
Published: October 2024

Introduction:

A binuclear azomethine quinoxaline Schiff base copper (II) complex, [Cu2LCl2], having square-planar environment around each copper (II), has been synthesized.

Method:

The coordination of the azomethine quinoxaline Schiff base with copper (II) and its structure was studied by various physicochemical and spectroscopic measurements.

Results:

Catalytic activity of this complex in phenol hydroxylation reaction has been examined using H2O2 as a green oxidant.

Conclusion:

Catalytic reaction conditions were optimized and under these conditions, 18.32 % conversion of phenol has been obtained for this catalyst
Munkaerő-piaci mutatók elemzése az Észak-Alföld régióban 2018 és 2022-es években
Authors: Csástyu Lilla
Published: October 2024

In my study, I analyze the labor market indicators of the North Great Plain statistical region for the years 2018 and 2022 in order to map the regional labour market characteristics based on the indicators. One method of the analysis is the Beveridge curve. This complex analysis method graphically illustrates the evolution of the relationship between the unemployment rate and the proportion of vacant positions typical of the region under investigation. The results of the analysis can draw attention to possible problems in the labour market in the region. I examine the secondary statistical data in parallel with the available related literature.
Ten years’ experience of vacuum systems in treatment of complicated postoperative wounds of various etiologies
Authors: Cherkasov M. F. , Galashokyan K. M. , Startsev Yu. M. , Cherkasov D. M. , Melikova S. G. , Rudkova K. E.
Published: October 2024

Objective: increase effectiveness of wounds treatment after various etiology by using VAC.Materials and methods: study included 128 patients with surgical infection. Specter of operations is presented: pilonidal cyst excision — 40 (31.2%), sternomediastinitis — 23 (18%), mesh hernioplasty — 16 (12.5%), laparotomy — 15 (11.7%), emergency laparotomy — 7 (5.5%), traumatology paraimplant complications — 7 (5.5%), abdominoplasty — 7 (5.5%), postoperative esophageal fistulas — 6 (4.7%), decubital ulcers — 4 (3.1%), mammoplasty — 3 (2.3%).Results: duration of VAC-therapy averaged 22.1±0.26 days. Systemic inflammatory reaction noted in 43 (33.6%) patients. Granulation tissue on 8th day of treatment noted in 98 (76.6%) cases. Microscopically, on day 8 of treatment, inflammatory-regenerative cytograms were detected in 104 (81.3%) patients. Over the course of 16 days, wounds decreased by 62.1±2.5% in all observations. In 47 (36.7%) cases, secondary sutures were applied, in 30  (23.4%) — grafting. A month later, healing was noted in 106 (82.8%) patients. Complications (wound bleeding) were noted in 7 (5.5%) patients. Reoperations were performed in 11 (8.5%) patients. Period of complete healing was 29.3±0.4 days.Conclusions: vacuum therapy is an effective way to treat wounds in purulent surgery. Time of complete reparative regeneration of wound and period of expensive inpatient treatment are reduced.
To study the features of vegetative homeostasis in patients with ankylosing spondylitis with anxiety-depressive spectrum disorders
Authors: Blaginina I. I.
Published: October 2024

Objective: study of indicators of vegetative homeostasis and psychosocial functioning in patients with ankylosing spondylitis (AS) with anxiety-depressive spectrum disorders (RTDS).Materials and methods: the study involved 112 patients with AS in whom the presence of RTDS was assessed according to the Taylor, Hamilton, Spielberger scales, autonomic disorders by testing according to the methods “Wayne-patient” (VP) and “Wayne-doctor” (BB), heart rate variability (HRV), quality of life (QOL) and clinical and laboratory activity of the disease.Results: the majority of patients with AS showed signs of RTDS, while this category of patients showed signs of autonomic dysfunction, lower indicators of vital activity, the ability to adapt social functioning and the level of mental health. The HRV indicators obtained in this category of patients indicate an imbalance of sympathetic and parasympathetic influences with the dominance of the sympathetic link of regulation, which confirms the correlation analysis.Conclusions: patients with AS with RTDS are characterized by low vital activity, reduced adaptation to social functioning, depletion of antioxidant potential. They are characterized by a deterioration in HRV indicators with a predominance of the sympathetic link of the ANS, low resistance to psychoemotional stress with a predominance of the defensive component in the structure of vegetative security.
Sodium Triphosphate Effect on Encapsulation of Vitamin B6 into Chitosan-Alginate Nanoparticles and Its In Vitro Drug Release Study
Authors: Rahman Aulia , Suherman Suherman , Suratman Adhitasari
Published: October 2024

The in-vitro drug release study of vitamin B6 encapsulated into sodium tripolyphosphate crosslinked chitosan-alginate (B6-TCA) nanoparticles aims to determine the effect of sodium tripolyphosphate on the encapsulation efficiency of vitamin B6 and effectiveness of the nanoparticles to release vitamin B6. The focus of this research is synthesizing and characterizing TCA nanoparticles to encapsulate vitamin B6 as an effective delivery system by studying the kinetics release of vitamin B6. The research resulted in the formation of coarse solid powder nanoparticles in yellowish-white color with a nanoparticle size of 22.55 nm. Sodium tripolyphosphate decreased the percentage of encapsulation efficiency in the B6-TCA nanoparticles as its concentration increased. However, the increasing sodium tripolyphosphate causes a slower release of vitamin B6 from nanoparticles. The encapsulation efficiency of vitamin B6 is 82.04%. The optimum composition of B6-TCA nanoparticles ratio is 2:1:1.5:2, where Korsmeyer-Peppas kinetics model suited its better with the Fickian diffusion mechanism of 0.989 and has the smallest reaction rate constant of 0.039 occurred within 6 h.
Preparation of Titanium Dioxide (TiO2) from Waste of Polymetallic Ore Processing via Sulfurization Treatment
Authors: Otgon-Uul Enkh-Uyanga , Baatar Munkhtsetseg , Nanzad Ulziijargal , Lkhamsuren Jargalsaikhan
Published: October 2024

Various experimental conditions were applied to extract titanium oxide from the waste of polymetallic ore. X-ray diffraction (XRD) analysis confirms that the waste of polymetallic ore contains including various minerals such as almandine (Fe,Mg,Ca)3Al2Si3O12, brownmillerite (FeAlO3(CaO)2), quartz (SiO2), magnetite (Fe3O4). Using H2SO4 acid with a concentration of 93% in the S/L mass ratio of 1:1.5 at 140 °C is suggested as an optimum reaction condition. Its hydrolysis subsequently leads to the formation of the titanyl sulfate (TiOSO4), and relatively pure titanium oxide is obtained through precipitation and calcination at 600 °C. The observed band gap value of 3.2 eV for the obtained TiO2 corresponds to the typical band gap value of anatase-type TiO2. We calculated the crystallite size of extracted anatase-type titanium oxide according to the Debye-Scherrer equation it was determined to be 96.35 nm. Fully reflecting X-ray fluorescence (XRF) determined that the purity of extracted TiO2 is 93.18%. This report presents a newly developed process that enables the production of relatively high-purity TiO2 (93.18%) from the waste of polymetallic ore (TiO2 5.39%) by a simple sulfurization process.