bluuebunny/crossref_metadata_2025 huggingface dataset:
Patrimonio-territorial arqueológico en el distrito de Yarusyacán, Pasco, Perú
Authors: Altamirano-Enciso Alfredo José , Batista da Costa Everaldo
Published: September 2024

Parcanga constituye un ejemplo de patrimonio-territorial y territorio de excepción latinoamericano, ubicado a 3.750 m s. n. m. en el distrito de Yarusyacán, Pasco, Perú. Es un complejo arqueológico con pinturas rupestres o quilcas de círculos concéntricos de la religión andina del wak´anismo, contemporánea con Chavín. El objetivo de este estudio es analizar las funciones que tuvo el sitio arqueológico de Parcanga y que permitan transformar al pueblo de Yarusyacán mediante la educación y el turismo, en la construcción de un centro de interpretación, de resistencia cultural y de la mirada del giro descolonizador. Para ello, se utilizó como metodología de campo la prospección, el levantamiento planimétrico del sitio y su registro fotográfico. Se concluyó que el lugar fue un centro religioso del período Formativo Medio (800-300 a.C.), relacionado con el culto a la Pachamama o al Imaymana Wiracocha, representados en forma de serpiente femenina repleta de círculos concéntricos, cuyos ojos simbolizan al mito etiológico de los yarusyacanes.
Evolução hominínia: o que revela o tamanho dos dentes posteriores?
Authors: Neves Walter , Valota Leticia
Published: September 2024

A dentição tem grande importância para o estudo da evolução humana devido ao seu alto grau de preservação no registro fóssil e a sua capacidade de fornecer informações acerca dos indivíduos. Este trabalho busca identificar aspectos taxonômicos e relações evolutivas entre as espécies da linhagem humana a partir de uma análise fenética baseada em dados métricos da dentição posterior maxilar e mandibular, comparando-a com as ideias prevalecentes na literatura. As espécies incluídas abrangem os sete milhões de anos da evolução hominínia (totalizando 498 espécimes) e foram estudadas por meio de Análise de Componentes Principais. Além de fornecerem informações sobre o tamanho comparativo dos dentes de cada espécie, os resultados obtidos permitem que sejam discutidos o status hominínio do Sahelanthropus tchadensis, a relação de ancestralidade-descendência entre Australopithecus anamensis e Australopithecus afarensis, e o status taxonômico das espécies Australopithecus garhi, Australopithecus sediba, Homo rudolfensis, Homo antecessor e Homo naledi.
Sítios Arqueológicos Históricos do Litoral Pernambucano: Uma busca pela continuidade das ações de preservação
Authors: Barthel Campello Cecília , Duarte Milena , Nogueira Rúbia , Lins Marcelo , Alves Jr. Domingos , Oliveira Alessandra , Lopes Gleyce , Serrão Marcelo , Soares Igor , Rocha Lucas , Ibson Rodrigo , Sial Vanessa , Monteiro Paula
Published: September 2024

Este artigo apresenta uma análise do processo de patrimonialização de bens arqueológicos do período colonial localizados no litoral do estado de Pernambuco. A questão central trata da aplicabilidade dos processos de gestão instituídos pela Política do Patrimônio Cultural Material (PPCM) de 19/09/2018, no contexto do patrimônio arqueológico. Consideramos o processo de patrimonialização com base em três momentos do patrimônio: a situação do sítio anterior às pesquisas arqueológicas; o sítio como objeto de pesquisas arqueológicas; e o sítio diante de medidas e ações implementadas após as pesquisas, observando-se a continuidade ou não das ações de preservação. A análise considerou a integração do sítio arqueológico na paisagem contemporânea com base na compreensão do tempo presente na abordagem desses bens, a leitura do território e das dinâmicas sociais presentes ou não, além do estímulo ao fortalecimento dos grupos sociais. Na esfera mais prática, considerou-se aspectos relativos a  acessibilidade, a proteção de sua estrutura física e construção de ações para a conservação integrada. Com base nos parâmetros estabelecidos pela PPCM e na proposta de método para análise adotado nesta pesquisa, parametrizamos os dados, através da síntese de  atributos que permeiam uma maior complexidade e contextualização de cada bem, que permitiu a compreensão do panorama geral da gestão dos sítios arqueológicos históricos localizados no Litoral Pernambucano.
Fogo na toca: Uso do fogo e antracologia na Toca do Sítio do Meio (Piauí, Brasil)
Authors: Mota Leidiana , Scheel-Ybert Rita
Published: September 2024

Este trabalho apresenta uma síntese das pesquisas arqueológicas desenvolvidas ao longo de mais de 40 anos na Toca do Sítio do Meio (Piauí, Brasil) e os resultados de análises antracológicas. Esse sítio, com uma rica cultura material, apresenta evidências de ocupação desde c. 29.000 anos cal BP até o período histórico. As estruturas de combustão (fogueiras e manchas de combustão) destacam-se entre os vestígios arqueológicos, demonstrando o importante papel que o fogo teve durante a ocupação. Portanto, com o objetivo de compreender os usos do fogo nesse local e o uso da flora implicada nesse processo, realizamos análises antracológicas preliminares sobre fragmentos de carvão coletados durante as escavações. Os resultados indicam que os grupos praticavam uma coleta de lenha oportunista nas formações vegetais de floresta semidecídua próxima do abrigo, no cerrado e na caatinga.
O Sítio Rio Platê I: Análise tecnológica de uma coleção cerâmica Jê Meridional do Alto Vale do Itajaí (SC)
Authors: Abrahao Gonzaga Francisco
Published: September 2024

O presente texto reúne parte dos resultados da minha pesquisa de mestrado (GONZAGA, 2022), cujo objetivo foi revisitar a tecnologia da cerâmica associada aos povos Jê Meridionais em Santa Catarina a partir de estratégias metodológicas diversificadas. Aqui, será dado destaque ao material cerâmico do Sítio Rio Platê I (SC-VI-19), situado dentro da Terra Indígena Laklãnõ Ibirama, no Alto Vale do Itajaí/SC, detalhando a metodologia de análise privilegiada para a coleção e os resultados obtidos, que permitiram refletir sobre aspectos fundamentais da cadeia operatória desse tipo de cerâmica no contexto catarinense.
SISTEM PARIWISATA MANCINGAN RICE TERRACE TAMPAKSIRING SEBAGAI DAYA TARIK WISATA BUATAN BERBASIS MASYARAKAT
Authors: I Nengah Alit Nuriawan  , I Made Sukandana  , Ni Kadek Ari Cahyani
Published: September 2024

Mancingan Rice Terrace holds potential as a community-based artificial tourist attraction that supports sustainable tourism through a Community-Based Tourism (CBT) approach. This study aims to evaluate the tourism system at Mancingan Rice Terrace, focusing on the role of local communities in management, the development of artificial attractions, and tourism's economic, social, and environmental impacts. A qualitative-descriptive approach was employed to analyze community involvement in destination development and their contribution to tourism sustainability. The findings reveal that artificial attractions, such as trekking paths, photo spots, and agricultural education programs, have enhanced the site’s appeal and boosted local economic growth. Active community participation has not only created jobs but also preserved environmental sustainability. However, challenges such as inadequate promotion and infrastructure remain obstacles to further tourism development in Mancingan Rice Terrace. Recommendations for strengthening promotion, community training, and infrastructure improvements are proposed to ensure more effective and sustainable tourism management. This research provides insights into the importance of community collaboration in developing sustainable artificial tourist attractions.
Perfil de intervenções farmacêuticas realizadas na clínica cirúrgica
Authors: Galvão Raquel da Silva , Carvalho Camila Maciel de , Lima Gedson Rodrigues de Morais , Silva Géssica Teixeira da , Cardoso Flávia Pessoa de Belmont Fonseca
Published: September 2024

Objetivos: Caracterizar e identificar os principais tipos de intervenções farmacêuticas (IF) na clínica cirúrgica, demonstrar o perfil das IF e elencar os principais medicamentos envolvidos. Métodos: Estudo observacional transversal, quantitativo, descritivo e retrospectivo, fundamentado na análise de dados secundários. A amostra foi composta por todas IF realizadas no período estabelecido. Não houve distinção de sexo, idade ou doença e nenhuma IF foi excluída. Os dados foram analisados pelo Microsoft Office Excel® 2021, sendo aplicadas técnicas de estatística descritiva, como frequência total e análise temporal da média, mediana e desvio padrão. Resultados: Houve 1.663 internações e foram constatadas 464 IF, das quais 95,3% foram aceitas e 4,7% não foram aceitas. As principais IF foram de tempo de infusão (28,4%), diluição (18,3%), conciliação medicamentosa (17,9%) e posologia (11%). A principal classe de medicamentos envolvida foi do sistema digestivo e metabolismo (31,5%), sistema nervoso (28,1%) e anti-infecciosos de uso sistêmico (17,9%). Conclusão: Diante dos resultados, pode-se observar uma compreensão sobre as IF de uma clínica cirúrgica, destacando o papel crucial do farmacêutico clínico na promoção da segurança do paciente e na otimização do tratamento medicamentoso.
Perfil das ocorrências de hemorragia pós-parto em puérperas assistidas em uma sala de parto de alto risco
Authors: Silva Nathalya Anastacio dos Santos , Araújo Viviane Maria Gomes , Silva Nivia Alves da , Moura Nívea Alane dos Santos , Moraes Camila Tayse de Lima Silva , Silva Heloísa Simões da , Lima Maria Andrelly Matos de , Santana Tuanny Caroline Pereira de , Corrêa Thaís Albuquerque , Santos Amuzza Aylla Pereira dos
Published: September 2024

Objetivo: Identificar o perfil dos casos de hemorragia pós-parto na maternidade descrever a assistência prestada. Métodos: Estudo transversal do tipo descritivo, exploratório com abordagem quantitativa. A pesquisa foi desenvolvida com mulheres que desenvolveram hemorragia pós-parto em uma instituição filantrópica referência no atendimento materno-infantil no âmbito do Sistema Único de Saúde (SUS). Resultados: Os dados encontrados foram: (53,94%) que a via de parto com maior prevalência de Hemorragia Pós-Parto (HPP) foi a via de parto cesáreo. A causa da HPP, em grande maioria foi por atonia uterina (88,23%), e em alguns casos não apenas um fato isolado, houveram atonia e trauma, atonia e trombina, trauma e tecido. A massagem uterina e a curagem foram os principais manejos utilizados na resolução da HPP com um percentual de (40,00%). As medicações mais utilizadas foram ácido tranexâmico, ocitocina e misoprostol (52,94%), e (51,76%) dos casos foram resolvidos e encaminhados a enfermaria. Conclusão: O perfil das ocorrências da hemorragia pós-parto foi o seguinte acontecem mais em partos cesáreos, porém o quantitativo de partos instrumentais que tiveram a HPP como desfecho também alto, a maioria das mulheres tiveram a intercorrência foram mulheres primigestas, e mulheres que tiveram gestações únicas.
Disfunção erétil secundária à COVID-19
Authors: Carvalho Clarissa Fachetti , Oliveira Daniel Lucca Caetano de , Bernardes Erick Martins , Melo Maria Luiza Arrais de Alcântara , Gonçalves Itamar Magalhães
Published: September 2024

Objetivo: Realizar uma análise epidemiológica com dados da disfunção erétil em decorrência da COVID-19. Métodos: Trata-se de uma revisão integrativa, realizada a partir de um levantamento bibliográfico nas bases de dados PubMed (U.S. National Library of Medicine) e SciElo (scientific electronic library online) com os seguintes descritores: ‘’Disfunção Erétil, Covid-19’’ e seu equivalente em inglês ‘’Erectile Dysfunction, Covid19’’, correspondentes ao período de 2021 a 2023. Para seleção dos estudos, foram lidos artigos grátis disponíveis nas plataformas publicados no período supracitado nos idiomas inglês e português. Além disso, foram excluídos artigos que estivessem dissonantes com os descritores, assim como estudos que não fossem grátis e os que foram publicados fora da data alvo. Resultados: Foram pleiteados 128 estudos com base nos descritores, entretanto, após aplicados os critérios de inclusão e exclusão, apenas 6 artigos foram selecionados para compor o corpo do presente estudo e, em seguida, submetidos à análise minuciosa para extração responsável e imparcial de informações. Conclusão: Os estudos analisados mostraram uma associação significativa entre a infecção prévia por COVID-19 e o risco aumentado de desenvolvimento de DE, especialmente após a recuperação. Além da importância de considerar os fatores psicológicos, como ansiedade e depressão, como contribuintes para essa condição.
Controle social na saúde pública: dinâmica de funcionamento do conselho de saúde em município piauiense
Authors: Eugênio Antônia Jaqueline da Silva , Sousa Lívia Karolynne Moura , Silva Júlio Araújo , Sousa Artemizia Francisca de , Carvalho Mailson Fontes de
Published: September 2024

Objetivo: Analisar a dinâmica de funcionamento do Conselho Municipal de Saúde de um município do centro-sul piauiense. Métodos: Pesquisa documental, de abordagem qualitativa, a partir dos documentos institucionais, utilizando análise categorial temática. Foram identificados documentos relacionados à criação, constituição e funcionamento do conselho, e analisadas a frequência e os temas discutidos em suas reuniões do período de 2013 a 2022. Resultados: Foram registradas 151 reuniões, abordando um total de 517 assuntos. Esses assuntos foram agrupados em sete categorias temáticas: prestação de contas financeiras, programas e projetos, fiscalização e acompanhamento de ações e serviços, organização administrativa, ações de informação, informes e outros. Os resultados indicam que conselho analisado está em conformidade com as normativas e apresentada queda no quantitativo de reuniões no período da pandemia, além de predominância de discussões relacionadas à aprovação de prestação de contas financeiras da Secretaria municipal de saúde, o que sugere um viés cartorial de seu funcionamento. Conclusão: Destaca-se a necessidade de ampliar as discussões no conselho sobre questões estratégicas e políticas para melhorar a atuação na formulação e execução das políticas de saúde. Essas limitações refletem uma crise no controle social da saúde pública, observada em vários municípios e estados do Brasil.
A expansão dos cigarros eletrônicos e suas implicações clínicas
Authors: Santos Gabriela Brito , Miranda Lais Trigo , Boy Larissa da Costa , Marçal Nayara Trigo , Laignier Renan Pinheiro
Published: September 2024

Objetivo: Reunir e descrever as principais repercussões clínicas que o consumo excessivo dos cigarros eletrônicos pode causar na saúde e qualidade de vida dos usuários. Revisão bibliográfica: O uso de Cigarros Eletrônicos (CE) gera impactos negativos importantes no organismo humano. Os seus compostos químicos acometem, principalmente, o sistema pulmonar através do mecanismo de aumento de citocinas pró-inflamatórias. Além disso, também repercute nos sistemas cardiovascular, gastrointestinal, neurológico e oftalmológico, na saúde bucal e mental, bem como acarreta prejuízos se utilizado durante o período gestacional. Esses aspectos serão discutidos ao longo deste trabalho. Apesar das proibições da ANVISA, esses dispositivos continuam sendo comercializados clandestinamente, o que levanta preocupações sobre a segurança desses produtos. Considerações finais: Embora tenha surgido como uma alternativa para reduzir o consumo de cigarros convencionais, esses aparelhos apresentam efeitos adversos à saúde a depender da substância que é inalada. Portanto, é crucial promover maior clareza na fabricação desses dispositivos para assegurar e conscientizar os consumidores.
Automedicação com descongestionantes nasais: frequência de uso e conhecimento dos riscos e possíveis complicações
Authors: Viana Anne Gabrielle Dias de Miranda , Siqueira Jackeline Adlung , Cecílio Samyra Giarola , Pereira Larissa Mirelle de Oliveira
Published: September 2024

Objetivo: Avaliar o conhecimento dos estudantes de medicina de uma cidade do interior de Minas Gerais acerca das complicações orgânicas e da propensão ao efeito rebote decorrentes do uso abusivo dessas medicações. Métodos: Trata-se de estudo transversal, com análise de dados e fundamentação bibliográfica. A coleta de dados foi realizada por questionários, após a aprovação do Comitê de Ética em Pesquisa. Resultados: Há uma grande taxa de automedicação de descongestionantes nasais (47,2%) além do desconhecimento de seus efeitos colaterais, mesmo entre os estudantes da área da saúde. O primeiro período possui a maior taxa de alunos que fizeram uso de descongestionantes nasais por indicação médica, mas, também é o período com a maior porcentagem de uso entre os alunos do curso. E, ainda, a rinite alérgica é a condição médica que mais frequentemente levou ao uso de descongestionantes nasais. Conclusão: Apenas 23,62% dos estudantes alegaram conhecer os efeitos adversos do uso dos descongestionantes nasais, sendo taquicardia e dependência os mais citados. Por ser uma condição médica sem acometimento grave, mesmos os alunos da área da saúde não buscam orientação médica nem procuram se informar com relação aos princípios ativos, facilitando o desenvolvimento de complicações devido a uso indiscriminado.
Cordyceps sinensis 30c and Achyranthes aspera ointment in the treatment of molluscum contagiosum: A case series investigation
Authors: Arul Vettrivel
Published: September 2024

This study explores the effectiveness of a novel approach using a combination of Cordyceps sinensis 30C and topical Achyranthes aspera ointment in treating Molluscum contagiosum. The ointment was formulated by blending Achyranthes aspera Q with petrolatum, following standardized procedures. Two cases of Molluscum contagiosum were treated internally with Cordyceps sinensis 30C and externally with the Achyranthes aspera ointment. Treatment progress was closely monitored, and the modified Naranjo criteria were applied to assess the causal relationship between the treatment and clinical outcomes. Both cases showed significant improvement, with lesions disappearing within three months. The Naranjo scores indicated a potential causal link between the treatment and the observed outcomes. This combined approach offers a promising alternative in homoeopathy for managing Molluscum contagiosum, though further research and larger clinical trials are necessary to confirm its efficacy and safety. The integration of external applications in homoeopathy remains a subject of debate, yet this approach aligns with evidence-based practices, potentially improving patient care.
On the institutionalization of Russian pulmonology: the second and third stages of its history
Authors: Borodulin Vladimir I. , Banzelyuk Egor N. , Topolyanskiy Aleksey V.
Published: September 2024

For the first time, the authors conducted a historical analysis of primary sources and identified 3 stages in the history of Russian pulmonology, naming 8 of its founders. The content is disclosed in two articles (the first one was published in No. 3 of our journal for 2024). This article tells about the second (pulmonology as an independent scientific and educational discipline within the clinic of internal diseases) and the third (as a new medical specialty) stages of the history of Russian pulmonology in the XX century.
Cytomegalovirus infection in gastroenterology
Authors: Maev Igor V. , Velikolug Konstantin A.
Published: September 2024

Aim. To highlight the relevance of gastrointestinal manifestations of cytomegalovirus infection (CMVI), to highlight the main risk factors for the development of this pathology, current trends in diagnosis and treatment.
Key points. CMVI is one of the most common opportunistic diseases, characterized by a variety of manifestations from asymptomatic to severe generalized forms affecting internal organs and body systems. The prevalence of CMVI worldwide ranges from 20 to 95%. Particular attention is paid to timely diagnosis, treatment and prevention of CMVI. The “gold standard” in the diagnosis of digestive diseases associated with CMVI is immunohistochemical examination and detection of cytomegalovirus (CMV) DNA in tissues using the polymerase chain reaction (PCR). Of undoubted interest in the diagnosis of CMV is the detection of CMV DNA in stool using digital PCR. Compared to quantitative PCR, digital PCR has higher accuracy and sensitivity. As first-line therapy, the drugs of choice are ganciclovir and valganciclovir. Maribavir has been successfully used to treat patients with CMV infection refractory to one or more previous therapies. One of the promising directions in the treatment of cytomegalovirus colitis in patients with ulcerative colitis is fecal microbiota transplantation.
Conclusion. Timely identification of risk factors for the development of CMV infection, the introduction of innovative methods and approaches in diagnosis, and the use of effective methods for treating diseases of the digestive system associated with CMV infection can improve the prognosis of the underlying disease and reduce the risk of developing urgent conditions in gastroenterology.
Personalized diagnosis of patients with gastroesophageal reflux disease using 24-hour pH-impedance testing and high-resolution esophageal manometry
Authors: Maev Igor V. , Yurenev Georgy L. , Barkalova Elena V. , Ovsepian Mariia A. , Andreev Dmitry N. , Shaburov Rafik I.
Published: September 2024

Aim. To determine the phenotypic variants of patients with symptoms of gastroesophageal reflux disease (GERD), non-erosive reflux disease (NERD), hypersensitive esophagus (HSE), functional heartburn (FH) using 24-hour pH-impedance testing and high-resolution esophageal manometry (HSEM).
Materials and methods. Fifty-five treatment-native symptomatic patients with newly diagnosed GERD and 48 control group subjects (CG) were examined. The mean age of the subjects was 45.0 years (95% confidence interval [CI] 41.0–48.9). Patients were grouped based on typical symptoms (heartburn, belching, regurgitation, odynophagy, dysphagia), medical history, endoscopy results, and 24-hour pH-impedance testing. Patients with typical symptoms of GERD and Grade B, C, D erosive esophagitis (EE) according to the Los Angeles Classification (LA) based on endoscopy were excluded from the further study. All patients without changes in the esophageal mucosa on endoscopy or with LA grade A EE (presumably NERD) underwent 24-hour pH-impedance testing and HSEM without proton pump inhibitors. Acid exposure, acid reflux count, symptom association with reflux (with symptom index and symptom association with reflux), mean nocturnal impedance, and post-reflux swallow-induced peristaltic wave index were assessed. The structure (presence or absence of a hiatal hernia) and function (presence or absence of the lower esophageal sphincter hypotonia) of the esophagogastric junction, as well as the motor function of the thoracic esophagus, were assessed using HSEM. The results of the HSEM were interpreted according to the Chicago Classification, 3rd edition (2015).
Results. The number of acid refluxes in patients with NERD was 71.0 (95% CI 58.4–83.7), in subjects with HSE – 38.5 (95% CI 28.3–49.0), with FH – 13.0 (95% CI 6.5–18.2), in CG – 16.5 (95% CI 9.0–21.0). The average nocturnal basal impedance was 1300 ohms (95% CI 1000–1986) in patients with NERD, 1725 ohms (95% CI 1338–2261) in patients with HSE, 2760 ohms (95% CI 2453–3499) in FH, 2515 ohms (95% CI 2283–2700) in CG. The index of post-reflux swallow-induced peristaltic wave in patients with NERD was 61% (95% CI 57–71), with HSE – 85% (95% CI 82–88), with FH – 71% (95% CI 64–78), in CG – 66% (95% CI 63–69). Hiatal hernia and/or hypotonia of the LES were more common in patients with NERD (23%) than in CG (13.3%). Ineffective motility was detected in 34% of patients with NERD, in 23% of subject with FH and in 66.7% of patients with HSE.
Conclusion. The results support the hypothesis that patients with GERD symptoms represent a heterogeneous population. 24-hour pH-impedance testing and HSEM helps to differentiate endoscopically negative patients with GERD symptoms and patients with Grade A EE by LA to NERD, HSE and FH.
Herbal extracts in hepatoprotection: antioxidant and immunomodulatory effects. A review
Authors: Shikh Evgenia V. , Khaytovich Evgeniy D. , Tsvetkov Dmitry N.
Published: September 2024

The global market for herbal medicines is valued at $83 billion and continues to expand rapidly. Plant extracts, widely used due to their safety and minimal side effects, play a significant role in supporting liver function. The treatment of liver diseases, including hepatitis of various etiologies, alcoholic and non-alcoholic fatty liver disease, and cirrhosis, involves the use of effective hepatoprotective drugs. Plant extracts provide antioxidant and immunomodulatory pharmacological effects that contribute to the maintenance of liver function. The aim of this review was to analyze the mechanisms underlying the hepatoprotective effects of various herbal extracts included in the formulation of DIPANA®, focusing on their antioxidant and immunomodulatory properties. Additionally, the review aimed to present clinical study results supporting their efficacy in treating of various liver diseases. The analysis was based on available literature data and clinical studies on the use of DIPANA®. The reviewed herbal extracts and their combination (DIPANA®) demonstrate efficacy in experimental models of liver damage and clinical studies involving patients with liver diseases, including alcoholic and non-alcoholic steatohepatitis, drug-induced liver injury, and functional disorders of the gallbladder. This drug exhibits hepatoprotective, choleretic, relaxing effects and is well-tolerated by patients.
Efficacy of rabeprazole for the treatment of gastroesophageal reflux disease in a 7-day non-interventional trial
Authors: Tsukanov Vladislav V. , Onuchina Elena V. , Vasyutin Alexander V. , Dambaeva Bairma B. , Tonkikh Julia L. , Pavlova Nadezhda V.
Published: September 2024

Aim. To evaluate the efficacy of seven-day treatment with rabeprazole (Razo®) 20 mg once daily in patients with NERD and esophagitis based on monitoring the results of pH-impedancemetry of the stomach and esophagus and assessment of clinical symptoms.
Materials and methods. Thirty patients with typical GERD manifestations were examined. The study included patients who underwent pH-impedancemetry, endoscopic examination, and were prescribed treatment with rabeprazole at a dose of 20 mg once a day. Clinical monitoring was performed during three visits: before treatment, after 3 days, and after 7 days of treatment. Control pH-impedancemetry was performed after 7 days of therapy. The third visit was the endpoint of the study.
Results. After 7 days of treatment, the response rate for heartburn was 86.7% in the overall group of patients with GERD, 94.4% in those with NERD, and 75.0% in patients with esophagitis stage A and B. After 7 days of therapy with rabeprazole, we registered a significant decrease in the total number of refluxes (from 88 to 54; p0.001), the number of acid refluxes (from 53 to 22; p0.001), the DeMeester index (from 23.81 to 7.62; p0.001), and AET (from 7.54 to 2.01; p0.001) in the esophagus and an increase in the median daily pH (from 1.8 to 5.4; p0.001) and the time with pH4 in the stomach (from 2.57 hours and 10.7% up to 12.3 hours and 51.3%; p0.001). 7-day therapy with rabeprazole was accompanied by a significant improvement in GERD patients in all parameters of quality of life. 100% of patients with GERD rated their satisfaction with therapy as “good” and “very good”.
Conclusion. As a result of 7-day therapy of patients with NERD and esophagitis with Razo® at a dose of 20 mg per day, an excellent clinical response was obtained, confirmed by a marked optimization of pH-impedancemetry parameters.
The reliability of insertion torque as an indicator for primary stability in immediate dental implant: A prospective clinical study
Authors: Dkheel Ikhlas A , Al-Quisi Ahmed F , AlOtaibi Noura
Published: September 2024

Background: The primary stability of the dental implant is a crucial factor determining the ability to initiate temporary implant-supported prosthesis and for subsequent successful osseointegration, especially in the maxillary non-molar sites. This study assessed the reliability of the insertion torque of dental implants by relating it to the implant stability quotient values measured by the Osstell device. Material and methods: This study included healthy, non-smoker patients with no history of diabetes or other metabolic, or debilitating diseases that may affect bone healing, having non-restorable fractured teeth and retained roots in the maxillary non-molar sites. Primary dental implant stability was evaluated using a torque ratchet from the dental implant kit and ISQ values generated from the Osstell device. Results: Twenty patients (13 female and 7 male) with an age range of 25-65 years received twenty immediate dental implants. The insertion torque value ranged from 15 to 50 N/cm with a mean of 28 N/cm. At the same time, the ISQ values ranged between 50 and 80 ISQ values, with a mean of 63 ISQ values. The results showed a statistically significant positive correlation between the insertion torque of the dental implant measured by torque rachet and ISQ values checked with Osstell. Conclusion: The insertion torque can be used as a reliable method to estimate the primary stability of the immediately inserted dental implants in the maxillary non-molar sites comparable to the Osstell device ISQ values. In addition, torque ratchet is readily available in the dental implant kit at no additional cost, making it a valuable choice over the Osstell device.
Evaluating the physical properties of microwave-cured and heat-cured acrylic denture base materials after the addition of ZrO2 nanoparticles.
Authors: Hasan Radhwan H , Aziz Rana R , Shehab Marwah M , Abduo Jaafar
Published: September 2024

Background: The structural, physical, and mechanical properties of denture-based acrylic resin are still compromised by water sorption, water solubility, and porosity. These issues have long called for improved techniques, and the use of nanoparticles is one of them. The main objective of the current investigation was to evaluate and contrast some physical parameters (water sorption, water solubility, and porosity) after the incorporation of ZrO2 nanoparticles (0%, 3% and 5%) into heat-cured acrylic denture base materials (Ivoclare, Major) and microwave-cured acrylic (Acron MC). Materials and methods: A total of 60 resin specimens were manufactured, including 5 specimens for each concentration of ZrO2 NP (30 for porosity and 30 for water sorption and solubility). Followed the manufacturer's directions for preparing the sample of each material. Results: The results were analysed with descriptive statistics, Analysis of Variance(ANOVA) test, Duncan multiple range test, and independent T test demonstrated that the addition of nanoparticles (3% and 5%) decreased water sorption, water solubility, and porosity of PMMA(polymethyl methacrylate) for both types(microwave-cured and heat-cured acrylic denture base materials). Where, at 3%, the ZrO2 nanoparticles showed the best values for all tests compared to the control group. Conclusions: ZrO2 (3% and 5%) nanoparticle reinforcement of acrylic resin can be a useful tactic for lowering water sorption, solubility and porosity, thereby enhancing the performance of the material in various applications for microwave-cured and heat-cured acrylic denture base materials.
Assessment of the salivary level of glutathione and the feeding pattern in molar incisor hypomineralization among 7-9 years of age: an analytical cross-sectional study
Authors: Salih Alaa H , Qasim Alhan A , Kolahi Jafar
Published: September 2024

Background: The study aimed to assess salivary glutathione levels and the pattern of feeding on molar incisor hypomineralization among healthy children aged 7-9 years. Materials and Methods: The study was a cross-sectional study. A total of 90 children sample was further sub classified into two groups: the study group, including 60 children with molar incisor hypomineralization, classified into two subgroups, 30 children with mild type and 30 children with severe type of molar incisor hypomineralization. In addition to the control group involving 30 children without incisor hypomineralization and free of caries. Examination and diagnostic criteria for hypominerlization of the molar incisor and assessment of severity were according to European Academy of Pediatric Dentistry (EAPD) guidelines in 2003. The salivary glutathione ELISA kit was used to assess the amount of glutathione in unstimulated saliva samples. After an oral examination, the parents of each child completed a self-administered questionnaire that included information on the child's feeding pattern during the first year of life. The questionnaires were returned to the researcher the following day. The child who received a mixed feeding pattern was excluded from the study. Results: The ordinal logistic regression model (Overall model test: p < 0.001) presented that salivary glutathione (p < 0.001), saliva pH (p = 0.014) and saliva flow rate (p = 0.009) were significant predictors of hypomineralization of the molar incisor. The feeding pattern (p = 0.625) and gender (p = 0.394) were not significant predicators for hypomineralization of the molar incisor hypomineralization. Conclusion: In children aged 7 to 9 years, salivary glutathione level is a negative predicator for the degree of hypomineralization of the molar incisor. Moreover, child feeding pattern, and gender, are not significant predicators of hypomineralization of the incisor hypomineralization.
Evaluation of titanium dioxide and tantalum pentoxide nanoparticles for coating NiTi archwires in orthodontics: An in vitro study
Authors: Mahmood Abeer B , Alhuwaizi Akram F , Khalaf Mohammed K , Zaher Abbas R
Published: September 2024

Background: This study aims to enhance the biocompatibility of Nickel–Titanium (NiTi) alloy by developing a new coating using titanium dioxide (TiO2) and titanium pentoxide (Ta2O5) through direct current (DC) reactive sputtering technology. Materials and methods: Two distinct coating materials, namely, TiO2 and Ta2O5, were used to fabricate NiTi orthodontic archwires with improved surface properties. TiO2 nanoparticles, with thickness ranging from 21.90 nm to 31.93 nm, were deposited onto NiTi alloy substrates through DC reactive sputtering deposition under different power conditions. Results: X-ray diffraction and field emission scanning electron microscopy validated the uniformity and morphology of the coatings. Immersion tests in simulated body fluid (SBF) revealed significant hydroxyapatite layer growth on TiO2-coated NiTi, especially at a sputtering power of 240 W. Reduced nickel ion release was observed on TiO2 nanoparticles with a thickness of 21.90 nm at 50 W sputtering power compared with 31.93 nm-thick nanoparticles at 240 W. Ta2O5 thin films were deposited on NiTi substrates through DC magnetron reactive sputtering at ~100 °C with a deposition power of 50 W. Structural and morphological analyses through optical microscopy and X-ray diffraction, atomic force microscopy, and scanning electron microscopy revealed the homogeneity and low roughness of the coatings. Biocompatibility assessments in artificial saliva and SBF solutions established that Ta2O5-coated NiTi alloys exhibited superior electrochemical behavior, enhanced corrosion resistance, and diminished Ni ion release compared with uncoated specimens. Conclusion: TiO2 and Ta2O5 coatings not only improved the biocompatibility of NiTi orthodontic archwires but also presented a promising path for advanced biomedical applications. These coatings have potential in improving the cellular behavior and performance of NiTi-based orthodontic devices.
A thorough assessment of 10-MDP primers in modern dental adhesive systems
Authors: Abduljawad Ahmed A , Salih Harraa SM , Tawfiq Omar F
Published: September 2024

Background: Dental primers are pivotal in achieving durable and reliable bonding between dental adhesives and tooth structures. Among the various primers’ components, the functional monomer 10-methacryloyloxydecyl dihydrogen phosphate is gaining significant attention owing to its unique chemical properties and bond-enhancing capabilities. Aims: This paper comprehensively reviewed current knowledge on the functional monomer 10-methacryloyloxydecyl dihydrogen phosphate. We focus on its chemistry, interactions with tooth substrates, interactions with zirconium and other metals, adhesive’s longevity, clinical applications, and potential drawbacks. Sources: Our sources are the Internet, such as Google Scholar and PubMed. Study selection: Studies investigating the efficacy of 10-MDP primers were included. Conclusions: The emergence of 10-MDP primers has significantly advanced the field of dental adhesives by providing reliable bonding solutions to enamel and dentin. The chemical interaction between 10-MDP and tooth substrates demonstrates remarkable adhesive strength and longevity.
The One Percent
Authors:   , Sunderland Emily
Published: September 2024

Our current land use, projected population and New Zealand’s ever-reducing biological capacity demonstrate an unprecedented design challenge. This thesis seeks to understand and interpret the significant role the built environment has in contributing to the world's carbon emissions and overall ecological footprint. This thesis begins by conducting a comprehensive analysis of biocapacity by critically analyzing its significance and implications within the ecological limits and trends of New Zealand for the future of 2048. The research highlights key issues of rapid urbanisation, density and population growth and how architectural issues exert pressure on our natural ecosystems through the proliferation of poorly designed built-up areas. These design issues result in environmental degradation, fragmentation, habitat destruction and loss of biodiversity.

With the world increasingly urbanizing, there is a growing need to incorporate nature-based solutions into building design to minimise or offset their negative impacts. This thesis follows a research-led design approach to explore sustainable frameworks, design philosophies and strategies, aiming to identify relevant design parameters and sustainable indicators. This research-led design is realised through the redesign of an urban block in an attempt to bring us closer to the Earth's Fair Share thereby preventing further biodiversity loss and mitigating the impacts of climate change on the urban built environment.
Augmented Text: A New Frontier in Comprehension
Authors:   , Bell Jon
Published: September 2024

What is Augmented Text?

It’s easy to read, but too hard to comprehend what you’re reading. Consider reading an engrossing novel on a beach. Compare that to the feeling of having 127 browser tabs open while trying to research a complex topic. On one hand, it's hard to find flow when you're being bombarded with information, which is where novels excel. On the other hand, it’s hard to comprehend dense content filled with jargon, which is where comprehension-aiding software excels. Augmented Text aims to take the best from both words, by combining the flow a person can experience while reading a novel with the power of comprehension-aiding software tools.

Research Objective This work addresses one question: How can we enhance the reading experience through technology without compromising the essence of traditional reading? It utilises a methodology that combines qualitative and quantitative approaches in order to quantify the "essence" of traditional reading with enhancements that benefit readers of educational and informational content.
Living on the street: sociodemographic, economic, and motivational aspects
Authors: Fernandes Márcia Astrês , Santos João Gabriel Ribeiro dos , Costa Ana Paula Cardoso , Pillon Sandra Cristina
Published: September 2024

Objective: To assess sociodemographic and economic aspects and motivations for living on the streets. Methods: A cross-sectional study of 127 homeless people in the city of Teresina, Piauí, Brazil. Data were collected in person between October 2019 and March 2020. A descriptive analysis of the results obtained was performed. Results: The sociodemographic profile observed was that of male, single, brown, with children, with a low level of education and income. The main reasons for homelessness were family conflicts, use of psychoactive substances and unemployment. Conclusion: The phenomenon of homelessness is perceived as a broad and complex process influenced by biopsychosocial events that occur throughout the life cycle, which requires a holistic approach by health professionals towards people in this situation.
Loneliness and aging
Authors: Santos Ana Maria Ribeiro dos , Marques Maria do Céu Mendes Pinto
Published: September 2024

Scientific evidence on loneliness shows that this feeling can act as a decisive negative factor in maintaining health. In this sense, an editorial on the subject stated that the damage to health is clear and associated loneliness with an increased risk of cardiovascular diseases, hypertension, diabetes, infectious diseases, impaired cognitive function, depression and anxiety. The editorial also highlighted that this is an issue that requires society's attention and, as a result, a committee was created to study loneliness and social isolation.(1)
Due to the evidence of the harm it can cause or worsen, loneliness has become one of the major health concerns in the 21st century. As a result, initiatives have been developed and the governments of the United Kingdom and Japan created Ministries of Loneliness in 2018 and 2021, respectively.(2) Also, a health authority in the United States showed the consequences of insufficient connection for physical health and highlighted a 29% higher risk of heart disease, a 32% higher occurrence of stroke and a 50% higher chance of developing dementia in older people. In addition, it estimated that the lack of social connection increases the risk of premature death by more than 60%.(3)
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Synthesis and Characterization of Coordination Compounds with Novel Ligands: Implications for Material Science
Authors: Raman Raman
Published: September 2024

Coordination compound are any of a class of substances with produced plans where a central metallic particle is encircled by non-metal elements or social assemblies of particles, termed ligands. A basic use of coordination compounds is their use as motivations, which effectively change the speed of designed responses. This study researches the mix and depiction of coordination compounds incorporating novel ligands, with an accentuation on their ideas for material science. Coordination compounds, outlined by the coordination of a central metal atom or molecule with various ligands, are crucial for an extent of engineered and present day cycles. In this investigation, we detail the mix of a couple of coordination compounds featuring as of late made ligands. These ligands are planned to give express electronic and steric influences, smoothing out the introduction of the ensuing edifices.
STUDY ON ARTS, CRAFTS AND DANCES OF THE GOND COMMUNITY OF NUAPADA DISTRICT IN ODISHA
Authors: Majhi Hutasan , Mohapatra R.
Published: September 2024

The arts, crafts and dances of the people of Gond community of the Nuapada district are the significant aspects of the tribal cultural heritage of Odisha in India. This study is focusing on the rich cultural heritage of the Gonds residing in the Nuapada district of western Odisha particularly their art, paintings, craft, and dances. The Gond tribe people is known for decorating the exterior walls of their houses with intricate artwork believed to bring respectable providence. The research aimed to assess the knowledge of Gond art among the community near the Boden block of Nuapada district of Odisha, focusing on themes monogram patterns, designs, motifs, colours, media used, and institutions involved of the promotion of this art custom. The Maadli and Dalkhaiand Ghumura dances in particular are highlighted as a significant cultural expression among the Gond community of the Kalahandi and Nuapada districts, performed in honour of the deity Budha Deo through dance and song. The study emphasizes the urgent need for the preservation and documentation of the Maadli dance, which is on the verge of extinction of the Nuapada district. The Gond tribe of Nuapada is one of the major tribal communities of Odisha as well as Central India. The name “Gond” is derived from “Kond,” meaning green mountains of the Dravidian idiom of the Gond tribe. The painting is a popular folk art of the Gond tribe/ community of the Nuapada district of Odisha. The cultural heritage in the form of arts, crafts, songs and dances of Gond community is very interesting study for scholars as well as historians. So, the authors have taken modest venture to focus on the arts, crafts and dances of the Gonds of the Nuapada District in Odisha.
EXISTING LEGAL PROVISIONS IN INDIA FOR THE PROTECTION OF THE ENVIRONMENT: A STUDY
Authors: Jethani T.M. , Naidu S. T.
Published: September 2024

No constitution deals, with matters such as environmental protection, because any constitution contains only the rules of laws concerning the power structure, allocation, and manner of exercise. Besides Indian constitution is already a bulky document and brevity is the character of an ideal constitution. Hence from the point of view of the principles of constitutional law as well as the length of the constitution, it was impossible to have any Such Provision Safeguarding the healthy environment. Therefore, till the Subsequent amendment the constitution text of India was without any specific provision for the protection and promotion of the environment. However, the seeds of such provision could be seen in Article 47 of the constitution which Commands the state to improve the slandered of living and public Health. To fulfill this Constitutional goal, the state must provide a pollution-free environment. To afford better protection for the environment, the constitution was amended. The amended provided the following Article 48-A: By the constitution (42nd Amendment) Act, protection and improvement of environment and safeguarding of forest and wildlife. The State shall endeavour to protect and improve the environment and safeguard the forest and wildlife of the country. Article 51-A (g) – By Constitution (42nd Amendment) Act, 1976 It shall be the duty of every citizen of India to protect and improve the natural environment including forests—lakes, rivers and wildlife and to have compassion for living creatures.
THE ROLE OF MEDIA INFLUENCE ON THE JUDICIAL PROCESS IN INDIA: AN ANALYSIS
Authors: G Sudharsana Moorthy , Rao B Someswara , Naidu S. T.
Published: September 2024

In the bustling streets of Delhi, amidst the cacophony of vendors hawking their wares and the incessant honking of cars weaving through congested lanes, lies a cornerstone of India's democracy in the courtroom. Within its solemn confines, the wheels of justice turn relentlessly, unfolding stories of triumph, tragedy, and the pursuit of truth. Here, amidst the hushed whispers of legal arguments and the weighty pronouncements of judges, unfolds a tale as old as time as a clash of rights, a struggle for justice, and the delicate balance between law and morality. Yet, amidst this age-old drama, another character stealthily emerges, its presence weaving seamlessly into the fabric of the narrative of the media. Like an unseen hand guiding the plot from the shadows, media influence in the Indian judicial process has evolved into a formidable force, akin to a secondary protagonist in this theatrical production of justice. With its omnipresent gaze and insatiable appetite for stories, the media casts its spotlight on courtroom dramas, transforming legal proceedings into riveting spectacles that captivate the nation's attention.