bluuebunny/crossref_metadata_2025 huggingface dataset:
Temporary Tooth Separation to Improve Assessment of Approximal Caries Lesions: A School-Based Study
Authors: Nascimento MM , Ribeiro AP , Delgado AJ , Cassiano L , Caraballo MGD , Roulet J-F , Geraldeli S , Pereira PNR , Ottenga ME , Dilbone DA
Published: June 2020

Clinical Relevance

Radiographic lesion depth should not be used as the single determinant of the restorative threshold for clinically inaccessible approximal caries lesions. Temporary tooth separation is a feasible and effective diagnostic aid for assessment and appropriate management of approximal lesions.

In the era of tooth-preserving dentistry, the decision to restore approximal caries lesions must be based on the accurate assessment of tooth cavitation, as the accumulation of oral biofilms in these areas encourages lesion progression. However, lesions radiographically into dentin remain the main threshold criterion for restoring approximal lesions even though most of these lesions may not be cavitated. A school-based clinical protocol for temporary tooth separation (TTS) was developed to improve visual-tactile assessment and management of clinically inaccessible approximal lesions. TTS data retrieved from electronic health records were used to correlate radiographic lesion depth and surface cavitation status with lesion location and the patient’s caries risk and to evaluate the effectiveness of TTS as a diagnostic aid for approximal lesions. Of the 206 lesions assessed, 66.5% (n=137) were located in the maxillary arch, 56.6% (n=116) in distal surfaces, 61.3% (n=114) in premolars, and 21.5% (n=40) in molars. After tooth separation, 79.6% (n=164) of the lesions were diagnosed as noncavitated, including 90% (n=66) of the lesions radiographically at the inner half of enamel (E2) and 66% (n=49) of those at the outer-third of dentin (D1). Logistic regression analysis using E2 and D1 lesions showed no significant association between lesion depth or cavitation status with lesion location and caries risk. TTS is a feasible and effective diagnostic aid for the assessment and appropriate management of approximal caries lesions. There is a need to reevaluate the use of radiographic lesion depth as the single determinant of the restorative threshold for clinically inaccessible approximal lesions.
Data Resource: population level family justice administrative data with opportunities for data linkage
Authors: Johnson Rhodri David , Trinder Liz , Thompson Simon , Smart Jon , Lee Alexandra , Doebler Stefanie , Alrouh Bachar , Bedston Stuart , Akbari Ashley , Jones Kerina , Cusworth Linda , Broadhurst Karen , Ford David V , Griffiths Lucy J
Published: June 2020

Introduction

Better use of administrative data is essential to enhance understanding about the family justice system, and characteristics and outcomes for children and families. The Nuffield Family Justice Observatory Data Partnership supports this aim through analyses of core family justice datasets. When a child is involved in family court proceedings in Wales, Cafcass Cymru are employed to represent a child’s best interests.  This paper provides an overview of the Cafcass Cymru data, and linkage to population level health and other administrative datasets held within the Secure Anonymised Information Linkage (SAIL) Databank. Two data linkage example analyses are described. Further research opportunities are outlined.

Methods

Cafcass Cymru data was transferred to SAIL using a standardised approach to provide de-identified data with Anonymised Linking Fields (ALF) for successfully matched records. Three cohorts were created: all individuals involved in family court applications; all individuals with an ALF allowing subsequent health data linkage; and all individuals with a Residential Anonymised Linking Field (RALF) and Lower Super Output Area (LSOA) enabling area level deprivation analysis.

Results

Cafcass Cymru data are available containing 12,745 public law applications between 2011 and 2019, with 52,023 applications from 2005 to 2019 for private law. The overall match rate was 80%, with variations observed by time, law type, roles, gender and age. Forty per cent had hospital inpatient admissions 2 years prior or after application receipt at Cafcass Cymru, of which 27% were for emergency admissions; 54% had an emergency department attendance and 61% an outpatient appointment during the same period. Individuals involved in public or private law applications were more likely to reside in deprived areas.

Conclusion

The Nuffield Family Justice Observatory Data Partnership will enhance research opportunities to better understand the family justice system and outcomes for children and families. Population level Cafcass Cymru data can be accessed through the SAIL Databank. Forthcoming data acquisition will also facilitate further analyses and insight.
Recovery of Ammonium Metavanadate from Spent Catalyst
Authors: Aliwarga Lienda , Ramadianti Musadi Maya
Published: June 2020

Utilization of spent catalysts serves to meet the needs of vanadium and to overcome the environmental problem since vanadium is categorized as a hazardous, toxic material. Vanadium from the spent catalysts can be recovered in the form of V2O5 or NH4VO3. However, vanadate compounds (NH4VO3) are considered to be more valuable due to their higher price and easier production process, compared with V2O5. This study aims to find adequate operating conditions to obtain high yields and high purity of NH4VO3 crystals. The results showed that the presence of iron compounds in the extract made the crystals contaminated by brownish colour, so it decreased its purity. Therefore, iron compounds need to be separated first with precipitation. Crystals of NH4VO3 with yield of 60% on spent catalysts and purity of 75% were obtained by extraction using solvent Na2CO3 1.887 M for 60 minutes at room temperature with weight ratio of V2O5 in spent catalyst toward solvent volume (Rvp), 0.006 gram V2O5/mL Na2CO3. It was then continued by precipitation of iron compounds at pH of 12 for 2 hours and crystallization of NH4VO3 using NH4Cl 11.215 M for 4 - 5 hours at 60oC.
Self-Control of Adolescent in using Smartphone
Authors: Sari Indah Permata , Ifdil Ifdil , Sano Afrizal , Yendi Frischa Meivilona
Published: June 2020

Self-control is the ability to rule out or change responses in a person, as well as eliminate unwanted problems and refrain from doing anything necessary for adolescent in using smartphones. Self-control of adolescent in using smartphones in this study is viewed from aspects of self-discipline, deliberate / non-impulsive, healthy habits, work ethic and reliability. This study aims to describe self-control of adolescents in using smartphone. This research is a descriptive analytic study, with a sample of 246 adolescents at SMAN 2 Padang obtained using propotional stratified random sampling technique. The study used a questionnaire instrument complied using a likert scale mode. The results of this study indicate that self-control of adolescent in using smartphones is generally appropriate in the high category. This needs to be corrected and improved in order to avoid the negative effects of using a smartphone.
Resolusi Konflik Peternak Itik dengan Pemilik Sawah dan Masyarakat Kecamatan Bayang Kabupaten Pesisir Selatan
Authors: Afrinalsari Kartika , Susilawati Nora
Published: June 2020

Penelitian ini di latarbelakangi oleh fenomena konflik antara peternak itik dengan pemilik sawah dan masyarakat Kecamatan Bayang Kabupaten Pesisir Selatan. Tujuan dalam penelitian adalah untuk menjelaskan proses resolusi konflik peternak itik dengan pemilik sawah dan masyarakat di Kecamatan Bayang Kabupaten Pesisir Selatan. Penelitian ini di analisis menggunakan teori Konflik Sosial yang di kemukakan oleh Lewis A. Coser. Penelitian ini dilakukan dengan pendekatan kualitatif, teknik pemilihan informan purposive sampling dengan jumlah informan 14 orang. Pengumpulan data yang digunakan dalam penelitian ini observasi, wawancara, dan dokumentasi, teknik triangulasi data. Teknik analisis data menggunakan konsep Miles dan Huberman. Hasil penelitian menunjukkan: proses resolusi konflik antara peternak itik dengan pemilik sawah dan masyarakat di Kecamatan Bayang Kabupaten Pesisir Selatan. Proses resolusi konflik antara peternak itik dengan pemilik sawah dan masyarakat ada tiga tahapan yaitu negosiasi antara peternak itik dengan pemilik sawah dan masyarakat, mediasi dengan Datuak, dan albitrasi dengan Wali Nagari.
Dakwah Pemberdayaan Umat Perspektif Al-Qur`an
Authors: Zaeni Hassan , Mukmin Hasan , Syahril Sultan , Yanti Fitri , Aswadi Aswadi
Published: June 2020

This article aims to find out about: How the concept of preaching empowerment of the perspective of the Qur'an. This research is a type of library (library research) using the Thematic Interpretation approach. With the main source being the Qur'an, and focused on seven verses relating to da'wah and empowerment. And secondary sources in the form of books or books relating to the problem to be answered in this study. The results of this study reveal that the concept of empowering the people of The Qur'an perspective as follows. First, the mission of community empowerment aims to invite, order, direct, motivate to guide the target community (mad'u) to jointly make changes for the better oriented towards empowering and community independence, in order to realize shared happiness in the afterlife. Second, the context of empowerment in the Qur'an includes all aspects of both lahiriyah (material) and ruhiyah. In the lahiriyah aspect, it is carried out in the form of the construction of supporting facilities for community independence. In the aspect of empowerment, it is carried out in the form of education, recitation, etc. Third, the desired changes in the community will not be possible unless they start from each other by protecting and maintaining and developing their potential and environment that has been bestowed by Allah.

 

Artikel ini bertujuan untuk mengetahui tentang bagaimana konsep dakwah pemberdayaan umat perspektif al-Qurâ€™an. Penelitian ini merupakan jenis pustaka (library resech), dengan menggunakan pendekatan Tafsir Tematik. dengan sumber utama adalah al-Qurâ€™an, dan terfokus pada tujuh ayat yang berkaitan dengan dakwah dan pemberdayaan. Dan sumber skunder berupa kitab-kitab atau buku yang berkaitan dengan masalah yang akan dijawab pada penelitian ini. Hasil penelitian ini mengungkapkan bahwa konsep dakwah Pemberdayaan umat perspektif al-Qurâ€™an sebagai berikut. Pertama dakwah pemberdayaan umat bertujuan untuk mengajak, menyuruh, mengarahkan, momotivasi membimbing masyarakat sasaran (madâ€™u) untuk bersamasama melakukan perubahan ke arah yang lebih baik yang berorientasi pada pemberdayaan dan pemandirian masyarakat, dalam rangka mewujudkan kebahagian bersama di dunia akhirat. Kedua, Konteks pemberdayaan dalam al-Qurâ€™an mencakup seluruh aspek baik lahiriyah (material) maupun ruhiyah. Pada aspek ahiriyah dilakukan dalam bentuk pembangunan sarana-sarana penunjang kemandirian masyarakat. Pada aspek ruhiyah pemberdayaan dilakukan dalam bentuk pendidikan, pengajian dan lainya Ketiga, Perubahan yang diinginkan di masyarakat, tidak mungkin akan tejadi kecuali dengan dimulai dari diri masing-masing dengan cara menjaga dan memelihara serta mengembangkan potensi diri dan lingkungannya yang telah dianugrahkan oleh Allah Swt.
Upaya Perlindungan WNI oleh Pemerintah Indonesia melalui Pendekatan Diplomasi Digital (2014-2019)
Authors: Dharossa Tryas , Rezasyah Teuku
Published: June 2020

Peningkatan jumlah Warga Negara Indonesia (WNI) yang berada di luar negeri yang hampir selalu terjadi dari tahun ke tahun. Besarnya jumlah WNI yang berada di luar negeri ini kemudian menjadi sebuah fokus tersendiri yang harus diperhatikan oleh Pemerintah, terkait upaya perlindungan WNI yang berada di luar negeri. Oleh sebab itu, maka pemerintah perlu meningkatkan dalam memaksimalkan upaya perlindungan bagi WNI yang berada di luar negeri. Untuk itu, peningkatan upaya perlindungan WNI di luar negeri ini dapat dilakukan dengan menggunakan pendekatan diplomasi digital, dengan memanfaatkan kemajuan Teknologi Informasi dan Komunikasi (TIK) serta ketersediaan internet saat ini. Artikel ini bertujuan membahas bagaimana Diplomasi Digital yang dilakukan oleh Indonesia dapat diterapkan dalam upaya melindungi WNI yang berada di luar negeri. Peneliti menggunakan konsep diplomasi digital dari Marcus Holmes (2015) yang mengemukakan adanya penggunaan TIK, internet dan media social dalam pelaksanaan kebijakan luar negeri dan diplomasi. Peneliti menggunakan metode kualitatif yang dilakukan dengan studi literartur dan wawancara kepada beberapa narasumber yang dirasa relevan. Temuan dari penelitian ini adalah dengan diterapkannya diplomasi digital sebagai upaya perlindungan WNI di luar negeri, maka data yang diperoleh lebih kredibel dan proses pengaduan dan penyelesaian masalah pun dapat dilakukan dengan lebih efektif dan efisien.
Kerja Sama UNICEF dengan Indonesia dalam Mencapai Pendidikan Dasar Untuk Semua sebagai Tujuan Dua MDGs
Authors: Priyanka Ellissa , Heryadi Dudy
Published: June 2020

Riset ini bertujuan untuk menjelaskan bagaimana UNICEF dan Indonesia bekerja sama dalam mencapai pendidikan dasar untuk semua sebagai tujuan dua MDGs. Dalam menjelaskan fenomena ini, digunakan teori kerja sama internasional milik Zartman & Touval yang menyebut kerja sama sebagai situasi dimana para aktor dalam sistem internasional sepakat untuk melakukan kerja bersama agar dapat menghasilkan sesuatu yang tidak dapat dicapai apabila dilakukan sendiri demi kepentingannya. Riset ini juga didukung dengan teori organisasi internasional milik Weiss & Wilkinson yang mengemukakan tentang pentingnya kehadiran organisasi internasional dalam menciptakan kondisi kerja sama dan keuntungan kesejahteraan bersama guna mengidentifikasi dan menyelesaikan masalah melalui rancangan solusi tertentu dan membujuk orang lain untuk menerimanya. Riset ini dilakukan dengan metode penelitian kualitatif analisis deskriptif. Data yang digunakan dalam riset ini diperoleh melalui studi pustaka dan wawancara dengan pihak-pihak terkait.Hasil dari riset ini menunjukkan bahwa kerja sama UNICEF dengan Indonesia berhasil menyekolahkan kembali 17.000 anak usia sekolah dan meningkatkan angka indikator pencapaian pendidikan dasar setiap tahunnya melalui advokasi yang dilakukan UNICEF kepada pemerintah Indonesia.
What is the Diagnosis?
Authors: Dietrich Cristiano de Oliveira
Published: June 2020

A 83-year-old female implanted a double chamber pacemaker (Adapta DR) one year ago to threat a sinus node disease with symptomatic sinus arrest (up to 4,2s).
A tradição calvinista é intolerante? Uma breve contribuição à análise crítica da autorreferencialidade reformada | Is the Calvinist tradition intolerant? A brief contribution to the critical analysis of reformed self-reference
Authors: De Souza Robson Da Costa
Published: June 2020

Este artigo indica, sob uma perspectiva pós-estruturalista, uma possibilidade de articulação entre tópicos teológicos do calvinismo e seus desenvolvimentos posteriores, levando em conta, à luz do conceito laclauniano de articulação hegemônica, as questões engendradas nas tensas relações entre tolerância, intolerância e as lógicas autorreferenciais presentes na matriz teológica conservadora e dogmática de setores específicos do protestantismo brasileiro. Ainda, considera a viabilidade de uma releitura, desde a ótica pós-estruturalista, dos dinamismos culturais presentes nos ideais dessa nova forma de espiritualidade, com a indicação de uma alternativa ecumênica e progressista. Como a mistificação do discurso religioso protestante se baseia na ocultação, entre os fiéis reformados brasileiros, das instituições mais criativas e dinâmicas da Reforma, o texto caminha no sentido de uma “crítica imanente”, sem ignorar o destaque dado, na atualidade, à importância da gramática dos direitos humanos na consolidação de uma cultura pública secular, na dialética da secularização (e dessecularização).
How variations in concentrations of metal ions and suspended solids downstream river Rwabakazi in Uganda can be used to study pollution
Authors: Mukasa-Tebandeke, I. Z.  , Karume, I.  , Ssebuwufu, J.  , Wasajja , H. Z.  , Nankinga, R  , Habimana, M
Published: June 2020

Pollution is affecting river Rwabakazi in the Nile basin. Its effects are reflected by high turbidity, pH, total suspended solids, (T.S.S.), electrical conductivity, metal ions concentrations, and low concentration of dissolved oxygen (DO5). In this study, we report the variations in selected physicochemical parameters of waters of the Rwabakazi river.  Turbidity, pH, concentrations of selected metal ions, T.S.S., and DO5 of water sampled from three selected sites on the river in Kabale were very high. Mean DO5 fell from 96 ± 2 mg/L to 86± 1.5 mg/L downstream. The mean pH fell from 7.8 ± 0.03 to 7.6 ± 0.04, showing the removal of basic components. The turbidity dropped from370 ± 3 NTU to 305 ± 2 NTU, showing that the haziness of water decreased. The concentration of iron(II) fell from 320 ± 0.3 mg/L to 291 ± 0.2 mgL-1 indicating the fair extent of heavy metal ions downstream. The T.S.S. decreased from 330 ± 5 mg/L to 300± 5 mg/L, and concentrations of calcium and magnesium ions also decreased, providing evidence for self-purification. The available data suggests that river Rwabakazi is polluted as a result of poor agricultural practices, erosion, and flash flooding.  Further studies on nutrient and pesticide pollution of this river need to be carried out, and trees should be planted on steep open surfaces to minimize erosion.
La investigación de Enfermería en el primer nivel de atención
Authors: Arévalo-Ipanaqué Janet Mercedes
Published: June 2020

La salud pública en los países latinoamericanos presenta una problemática caracterizada por el limitado desarrollo de investigaciones. Se dice que, de cierto modo ello representa la marginalidad que tiene la salud pública dentro de las prioridades de investigación y la poca importancia que ha alcanzado en el desarrollo de las políticas públicas.
Is There a Nordic News Media System?: A descriptive comparative analysis of Nordic news audiences
Authors: Schrøder Kim Christian , Blach-Ørsten Mark , Kæmsgaard Eberholst Mads
Published: June 2020

In media systems theory, the Nordic countries are often held to constitute a specific media system (Brüggemann et al., 2014). In this article, we put this claim to the test in the area of news consumption. Based on findings about the four Nordic countries Denmark, Norway, Sweden, and Finland in the annual Reuters Institute Digital News Report (Newman et al., 2019), and inspired by previous studies of the audience dimension of media systems (Hölig et al., 2016; Peruško et al., 2015; Van Damme et al., 2017), we undertake a descriptive empirical analysis of the 2019 data of this 38-country study. Our study compares news audience practices in the Nordic countries with those of countries belonging to other supranational media systems. We find that while there are some internal differences within the Nordic media system, there are salient news consumption commonalities that are specific to the Nordic countries, such as preferred sources of news, pathways to news, paying for online news, and trust in the news.
(The domestication of) Nordic domestication?1
Authors: Hartmann Maren
Published: June 2020

The domestication concept, originally developed in Britain in the context of media appropriation in households’ everyday life, has seen a relatively high uptake in the Nordic countries from early on. This was by far not only an application of the concept, but an alternative interpretation with different emphases. I introduce two major strands of this uptake in this article: the Norwegian science and technology studies interpretation, and the primarily Finnish consumer and design research interpretation. These case studies will help answer the question of the degree of Nordicness in these interpretations of the domestication approach. In a last instance, the article aims to address the question what the current – and hopefully future – state of domestication research in the Nordic countries could look like.
Even in Sweden?1: Misinformation and elections in the new media landscape
Authors: Schroeder Ralph
Published: June 2020

The Swedish national parliamentary election of 2018 took place amidst considerable concern over the role of misinformation. This paper examines the role of digital media during the election against the background of the Swedish media system. It focuses on the role of bots and how they supported the Sweden Democrats, whose agenda was also promoted by anti-immigrant alternative news websites. This article reports on a study of Twitter that used computational techniques to distinguish bots from genuine accounts across hashtags related to the election and Swedish politics (such as #valet2018). I examine which parties are supported and criticised by bots and by genuine accounts, and discuss the content of the tweets. In this article, I place bots in the context of broader debates about the role of digital media in politics and argue that misinformation and alternative news websites will demand continued future vigilance.
Swedish Media Research in the Service of Psychological Defence During the Cold War?
Authors: Jakobsson Peter , Stiernstedt Fredrik
Published: June 2020

In this article, we address the history of Nordic media research through a case study of the formation of media research in Sweden in the 1950s and 1960s and the role that The Board for Psychological Defence played in the formation of Swedish academic media research during the Cold War era. Based on archival research, we find that the impact of the psychological defence on Swedish media research was mainly concentrated to one Swedish university, and that the impact on the theoretical and methodological development of the discipline has been rather limited. This distinguishes the Swedish case from what has been argued in historical research on the development of media and communication research in the US.
A Turn in the Road of Media Studies
Authors: Uricchio William
Published: June 2020

Whether in the form of Google searches, interactive games, or responsive textual environments, the reassuring subject-object binary so fundamental to the modern era's representation systems is fast slipping away. In its place, a recursive epistemological order that actively parses the subject and shapes the textual world is fast emerging, posing challenges to established notions of agency and to narrative as a cultural operating system. Assessments of the terms and implications of this shift will benefit from the distinctive analytic perspective that distinguishes the Nordic from many of its Anglo-American and European peers.
The Magic Spell and the Scent of Arabian Nights in Old China
Authors: Philippov Alexander V.
Published: June 2020

The proposed review analyzes the recently released four volumes of the Russian translation of the mysterious medieval Chinese novel “Chin Ping Mei” (in Russian, “The Plum in the Golden Vase”). The lengthy story written as a semi-erotic romance, can be compared with the best editions of “Arabian Nights” (in Russian, “A Book of A Thousand and One Nights”). The impressive edition depicts the life story of a lustful Chinese merchant who has devoted himself to spending his days among his wives, concubines and other “divas of amusement”. The profound publication includes a great amount of comments, remarks, scientific articles and original engravings. The new, impressively expanded (compared with the first 1977 edition in 2 volumes) scientific publication was prepared by several generations of Russian scholars in the field of Chinese studies. The editor-in-chief and supervisor of the project Artyom Kobzev (Moscow Institute for Oriental Studies) has provided a brilliant edition, having created an opportunity for a wider audience to become acquainted with a unique and educational history of ancient China.
Visit to Museums of North-East China
Authors: Voytishek Elena E. , Komissarov Sergey A. , Soloviev Aleksandr I.
Published: June 2020

The review contains information about the performances of employees of the Department of Oriental Studies of the Institute for Humanities of Novosibirsk State University and the Institute of Archeology and Ethnography of the SB RAS at international conferences, during which they also visited several important historical museums in northeast China. The review also touches on the famous Lamaist complexes of Inner Mongolia – Dalelinsi and Wudanzhao, the Hamin Archaeological Park with Neolithic burials, the Museum of Inner Mongolia in Baotou with its ethnographic collections, archaeological and historical materials from the Neolithic and Han eras to the New Age, as well as the Dafu Private Museum in Chaoyang (Liaoning Province), where the main local cultures of the Neolithic and Paleometal era are represented, many of which have been given the status of national Cultural Heritage of various levels.
Variety of large rearrangements in the CFTR gene in Russian patients with Cystic Fibrosis
Authors: Кондратьева Е.И. , Петрова Н.В. , Воронкова А.Ю. , Красовский С.А. , Амелина Е.Л. , Адян Т.А. , Черняк А.В. , Шерман В.Д. , Зодьбинова А.Э. , Каширская Н.Ю. , Зинченко Р.А.
Published: June 2020

Целью исследования стал анализ частоты протяженных перестроек гена CFTR и клинико-лабораторных характеристик пациентов с протяженными перестройками гена CFTR. В Регистр больных муковисцидозом РФ 2017 г. включены данные 3096 пациентов из 81 региона РФ, у которых выявлено 196 патогенных вариантов гена CFTR. Патогенные варианты обнаруживаются как в кодирующих, так и в интронных областях, и в регуляторных регионах гена CFTR. В гене CFTR относительно мало (около 2,5%) протяженных перестроек, но среди мутантных хромосом, в которых генетические варианты не были идентифицированы стандартными методами, такие перестройки составляют до 20%. По данным Регистра 2017 г. выявлен 21 пациент, несущий в своем генотипе крупные перестройки. Перестройки CFTRdele12,13del16, CFTRdele19-22(17а-19), CFTRdele8(7*), CFTRdele2-8(2-7*) ранее не были описаны в международных базах данных. Клиническая характеристика больных с протяженными перестройками не отличалась по основным признакам от пациентов с «тяжелыми» генотипами. Наличие в генотипе пациентов с протяженными перестройками варианта нуклеотидной последовательности гена CFTR, определяющего сохранную функцию поджелудочной железы, обусловило отсутствие у них панкреатической недостаточности.

The aim of the study was to analyze large rearrangements in the CFTR gene in patients with cystic fibrosis in the Russian Federation in 2017. The Cystic Fibrosis Patients Registry of the Russian Federation for 2017 includes data from 3096 patients from 81 regions of the Russian Federation. To date, more than 2,000 mutations or variants of the nucleotide sequence of the CFTR gene have been described. In the Cystic Fibrosis Patients Registry of the Russian Federation for 2017, 196 pathogenic CFTR variants are given. Pathogenic variants are found both in the coding and in the intron regions, and in the regulatory regions of the CFTR gene. The CFTR gene has relatively few (about 2.5%) large rearrangements, but among mutant chromosomes in which genetic variants were not identified by standard methods, such rearrangements account for up to 20%. According to the Registry of 2017, 21 patients were identified that carried large rearrangements in their genotype. The rearrangements CFTRdele12,13del16, CFTRdele19-22 (17a-19), CFTRdele8 (7*), CFTRdele2-8 (2-7*) are not described in international databases. The clinical characteristics of patients with extensive rearrangements in the genotype did not differ in basic characteristics from patients with “severe” genotypes. The presence of a genetic variant in the genotype that determines the preserved function of the pancreas leads to the preservation of gland function in patients with large rearrangements in the genotype.
Virtual Drug Repurposing Study Against SARS-CoV-2 TMPRSS2 Target
Authors: Durdagi Serdar
Published: June 2020

Currently, the world suffers from a new coronavirus SARS-CoV-2 that causes COVID-19. Therefore, there is a need for the urgent development of novel drugs and vaccines for COVID-19. Since it can take years to develop new drugs against this disease, here we used a hybrid combined molecular modeling approach in virtual drug screening repurposing study to identify new compounds against this disease. One of the important SARS-CoV-2 targets namely type 2 transmembrane serine protease (TMPRSS2) was screened with NPC’s NIH small molecule library which includes approved drugs by FDA and compounds in clinical investigation. We used 6654 small molecules in molecular docking and top-50 docking scored compounds were initially used in short (10-ns) molecular dynamics (MD) simulations. Based on average MM/GBSA binding free energy results, long (100-ns) MD simulations were employed for the identified hits. Both binding energy results as well as crucial residues in ligand binding were also compared with a positive control TMPRSS2 inhibitor, Camostat mesylate. Based on these numerical calculations we proposed a compound (benzquercin) as strong TMPRSS2 inhibitor. If these results can be validated by in vitro and in vivo studies, benzquercin can be considered to be used as inhibitor of TMPRSS2 at the clinical studies.
Total Chemical Synthesis of Aureocin A53, Lacticin Q and Their Enantiomeric Counterparts
Authors: Lander Alexander J. , Li Xuefei , Jin Yi , Luk Louis YP
Published: June 2020

Aureocin A53 (AucA) and lacticin Q (LnqQ) are class IId bacteriocins that display broad-spectrum activity against Gram-positive bacteria in the nanomolar range, of which their modes of action is unclear and their synthesis has not been reported. Here, we reported the chemical synthetic routes of AucA and LnqQ, enabled through the technique of native chemical ligation. To demonstrate the versatility of the syntheses, we prepared their enantiomeric counterparts, D-AucA and D-LnqQ, comprised of entirely D-amino acids. X-ray crystal structure of AucA obtained through racemic protein crystallography at 1.13 Å indicates unique Lys-Trp-sulfate network. This work lays foundations for gaining further mechanistic insights into these potent bacteriocins through total chemical synthesis.
A Chemical Perspective to the Anti-Amyloid Action of Compounds and a Nanoparticle Based Assay for Screening Amyloid Inhibitors
Authors: Gour Nidhi , Koshti Bharti
Published: June 2020

Aggregation of amyloid beeta 1-42 (Aβ42) peptide causes the formation of clustered deposits knows as amyloid plaques in the brain which leads to neuronal dysfunction and memory loss and associated with many neurological disorders including Alzheimer’s and Parkinson’s. Aβ42 has core structural motif with phenylalanine at the 19 and 20 positions. The diphenylalanine (FF) residue plays a crucial role in the formation of amyloid fibers and serves as model peptide for studying Aβ42 aggregation. FF self-assembles to well-ordered tubular morphology via aromatic pi-pi stackings. Our studies, suggest that the aromatic rings present in the anti-amyloidogenic compounds may interact with the pi-pi stacking interactions present in the FF. Even the compounds which do not have aromatic rings, like cyclodextrin and cucurbituril show anti-amyloid property due to the binding of aromatic ring inside the guest cavity. Hence, our studies also suggest that compounds which may have a functional moiety capable of interacting with the aromatic stacking interactions might be tested for their anti-amyloidogenic properties. Further, in this manuscript, we have proposed two novel nanoparticle based assays for the rapid screening of amyloid inhibitors. In the first assay, interaction between biotin-tagged FF peptide and the streptavidin labelled gold nanoparticles (s-AuNPs) were used. In another assay, thiol-Au interactions were used to develop an assay for detection of amyloid inhibitors. It is envisaged that the proposed analytical method will provide a simple, facile and cost effective technique for the screening of amyloid inhibitors and may be of immense practical implications to find the therapeutic remedies for the diseases associated with the protein aggregation.
中职学生接种流感疫苗与未接种疫苗的调查分析
Authors: 张 智梅
Published: June 2020

流感具有传播速度快、感染率高的特征，具体指的是由流感病毒所引起的急性呼吸道疾病，可以在密集的人群中爆发，影响人们正常的生活和工作，需要加强对流感病毒的防治。流感疫苗是常见的防治流感病毒的有效策略，论文主要针对中职学生接种流感疫苗以及未接种疫苗的调查进行研究，希望能够探究流感疫苗的作用和价值，加强对流感疫苗的探究，对于流感疾病的防治以及流感病毒的深入研发具有至关重要的作用。
胫骨髓内钉内固定术后膝关节疼痛的临床分析
Authors: 刘 中立
Published: June 2020

目的： 探究胫骨髓内钉内固定手术之后膝关节疼痛的临床原因以及具体的防治措施。 方法： 选取中国东光县医院在 2016 年12 月份到 2018 年 12 月份这两年时间内收治的部分经过胫骨髓内钉内固定术的 200 名患者作为研究对象，对研究对象的临床治疗情况以及膝关节疼痛发生情况进行分析。 结果： 这部分患者中有 100 名患者经过髌韧带内侧入路组膝关节手术，这组患者产生膝关节疼痛的有 25 名，对这 25 名的患者的膝关节疼痛原因进行分析与讨论，疼痛发生概率为 25%。另外 100 名患者经过髌韧带入路组，膝关节疼痛发生的人数为 28 名，疼痛发生率为 28%。 结论： 不同方式的胫骨髓内钉内固定方法并不能够减少术后膝关节疼痛的发生概率，疼痛发生率与操作的细节以及切口的大小有关。在临床进行筋骨髓内钉内固定术之后，需要对患者进行充分的护理，有效缓解术后膝关节疼痛问题，促进患者早日康复。
护患视角下胃肠外科术后患者隐私暴露现状的质性研究
Authors: 高 绍丽 , 张 芳芳 , 沈 艳 , 林 丽
Published: June 2020

目的： 了解护患视角下胃肠外科手术之后患者隐私暴露情况，并采取有效措施进行处理，有效维护患者的隐私，提高患者的满意度。 方法： 选取浙江金华广福医院于 2017 年 6 月份到 2019 年 6 月份这两年时间内收治的 200 名胃肠手术患者作为研究对象，进行隐私暴露情况的探究。调查手术之后患者对隐私部位保护的需求，并针对患者的实际需求开展有效的护理干预，提高患者对护理工作的满意度。选取本院 10 名护士作为访谈对象进行访谈，并提炼主题。 结果： 在护患视角下胃肠外科手术之后患者隐私暴露现状归纳为患者隐私暴露方式、心理反应以及保护需求三个方面。护患视角下对于隐私护理方式以及隐私保护需求方面存在认知上的差异，护患视角在隐私暴露的心理反应方面认知是一致的。 结论： 护士在进行胃肠外科手术之后患者护理过程中需要注意维护患者的隐私情况，认识到患者对隐私保护的要求以及重要性，有效维护患者的尊严，维护良好的护患关系，有效减少医患纠纷的发生，提高患者的满意度，促进患者的康复进程。
耳穴压豆联合黄连阿胶汤治疗阴虚火旺型糖尿病失眠 患者临床疗效观察
Authors: 石 燕萍 , 牛 少强 , 王 效非 , 韩 俊阁
Published: June 2020

目的： 观察耳穴压豆联合黄连阿胶汤治疗阴虚火旺型糖尿病失眠患者的睡眠改善情况。 方法： 将 2017.6-2018.8 就诊于我院阴虚火旺型糖尿病失眠患者 91 例，随机分为治疗组 46 例和对照组 45 例。两组在控制血糖等治疗的基础上，对照组给予患者西药等基础治疗；治疗组在对照组基础治疗上，给予患者耳穴压豆及黄连阿胶汤治疗；疗程为 8 周。使用 PSQI 观察两组患者治疗前后积分改善情况。比较两组患者治疗前后入睡时间、睡眠时长、睡眠质量及服用催眠药物频次的改善情况，并采用ISI 量表评定患者治疗前后失眠严重程度改善情况。 结果： 1. 两组治疗后，PSQI 评分均较治疗前降低（均 P < 0.05）；同期组间比较：PSQI 评分两组间比较无统计学差异（P > 0.05）。 2. 两组治疗后，入睡时间、睡眠时长及睡眠质量评分均较治疗前降低（均 P < 0.05）；同期组间比较：睡眠时间、睡眠质量评分治疗组较对照组降低更加明显（P < 0.05）。 3. 服用催眠药物方面同期组间比较，治疗组较治疗前明显降低（P < 0.05）。 4. 治疗前后 ISI 积分比较：两组治疗后，ISI 积分均较治疗前降低（P < 0.05）；同期组间比较：ISI 积分治疗组较对照组降低更加明显（P < 0.05）。 结论： 耳穴压豆联合黄连阿胶汤治疗阴虚火旺型糖尿病失眠患者可以有效改善糖尿病失眠患者的临床症状，改善患者的睡眠时间和睡眠质量，降低糖尿病失眠患者的失眠程度级别，且能有效地减少西药催眠药物的使用。
非营养性吸吮联合体位管理在早产儿喂养护理中的应用
Authors: 施 耿利
Published: June 2020

目的： 研究在早产儿喂养护理过程中非营养性吸吮联合体位管理的应用以及效果。 方法： 选取 2019 年 1 月至 2020 年 1 月我院收治的 200 例早产儿为研究对象，将其平均分为对照组和实验组两组，分别采用常规护理和非营养性吸吮联合体位管理相结合的两种方式，通过观察两组护理效果、恢复正常出生时体重、胃管留置时间、全胃肠道喂养时间几个指标分析两组护养结果差异。 结果： 实验组所得出的护理数据、护理结果、家长满意度要明显优于观察组，两组差异具有显著的统计学意义。结论： 通过运用非营养性吸吮联合体位管理能够有效提高早产儿的喂养护理效果、家长的护理满意度，能够保证早产儿的存活率。
青少年直肠粘液腺伴印戒细胞癌病例1例
Authors: 于 立科 , 范 晓燕 , 李 庆霞 , 康 林
Published: June 2020

目的： 总结 1 例青少年直肠粘液腺伴印戒细胞癌的临床表现、实验室检查、影像学检查及治疗过程，并进行文献复习。 方法：回顾性分析 2018 年 12 月中国河北省人民医院收治的 1 例青少年直肠粘液腺伴印戒细胞癌的临床资料，结合文献分析疾病诊治进展。应用中国知网 (CNKI)、万方数据库检索，以青少年、直肠、恶性肿瘤为关键词，并对检索出的文献病例资料进行总结。 结果： 青年结直肠癌患者发生比例较中老年患者低，但肿瘤恶性程度更高、分化更差。 结论： 本病例通过临床治疗过程严密观察和监测及患者预后情况，对于诊断为局部晚期的直肠粘液腺伴印戒细胞癌类恶性程度较高的青少年患者，治疗方案选择需要慎重和多样化。
2019 新型冠状病毒的三种检测方法探讨
Authors: 张 磊
Published: June 2020

新型冠状病毒（2019-nCoV）感染的肺炎突发疫情在中国已进入关键时期，国家相关部门每日通报确诊和疑似病例，启动重大突发公共卫生事件一级响应。该病毒具有极高的传染性，临床主要表现为新型冠状病毒肺炎（NCP）。目前，对该病毒的检测方法主要为核酸检测、CT 检测，特殊情况下可采用高通量测序检测。但每种方法均有一定的局限性，需根据病人的病情进展选择合适的检测方法。
激活素A抑制人骨髓瘤RPMI-8226细胞增殖的机制研究
Authors: 高 雅萱 , 单 奕迪 , 柳 忠辉 , 葛 敬岩
Published: June 2020

激活素 A 属于 TGF-β 超家族成员，具有抑制小鼠骨髓瘤细胞增殖、促进凋亡的作用，但对人骨髓瘤细胞的作用尚不清楚。本研究利用人骨髓瘤细胞系 RPMI-8226 细胞，采用 Cell Counting Kit-8 法检测激细胞活力，流式细胞术检测凋亡以及 PCR技术检测 mRNA 表达。实验结果发现，激活素 A 能够抑制 RPMI-8226 细胞活力，诱导 RPMI-8226 细胞凋亡，并且能够促进 ActRIIA 和 Smad3 的表达，提示激活素 A 通过作用于 ActRIIA-Smad3 抑制 RPMI-8226 细胞增殖。
妇产康复治疗仪治疗宫缩痛的护理疗效
Authors: 王 露影
Published: June 2020

目的： 分析对妇产科患者使用康复治疗仪对宫缩痛的护理疗效。 方法： 选取 2018.12 月 ~2019.12 月期间，因宫缩痛于我院接受诊治的妇产科患者 76 例作为本次实验的研究对象，并根据护理措施的不同分为对照组和观察组，每组患者各 38 例。使用常规护理的为对照组，使用针对性护理联合妇产康复治疗仪，对比分析两组患者的宫缩痛情况和护理满意度。 结果： 经数据分析处理后，对照组患者的宫缩痛发生率为 71.05%，明显高于观察组患者的宫缩痛发生率 5.26%，数据对比之间存在显著的差异，且（P ＜ 0.05），具有统计学意义。此外，对比两种护理措施下的患者满意度，观察组为97.36%，对照组为 71.05%，观察组明显优于对照组，数据差异显著，（P ＜ 0.05），存在统计学意义。结论： 对于宫缩痛的治疗，使用妇产康复治疗仪具有显著的改善效果，能够对患者的疼痛感情况起到有效的缓解，有助于患者的产后恢复，以及提高患者对护理工作的满意度，具有临床推广意义。
Konsentrasi Jahe Merah (Zingiber Officinale Rosc) Terhadap Karakteristik Fisikokimia Dan Organoleptik Daging Sayat Ayam Kampung (Gallus Domesticus)
Authors: Nafisah Lulu’
Published: June 2020

Daging ayam kampung mempunyai rasa yang lebih enak dengan kandungan lemak dan kolestrol yang rendah. Daging sayat merupakan salah satu cara efektif dalam proses pengawetan daging dengan cara curing dan pengeringan, penambahan bumbu rempah-rempah untuk memberi cita rasa dan aroma pada daging sayat. Jahe mengandung enzim protease yang mampu mengempukkan daging. Tujuan penelitian ini adalah untuk mengetahui pengaruh konsentrasi jahe merah terhadap karakteristik fisikokimia dan organoleptik daging sayat ayam kampung, mengetahui perlakuan terbaik yang dihasilkan. Penelitian ini dilaksanakan pada Bulan Juni-Juli 2019, di Laboratorium Rekayasa Pangan, Laboratorium Kimia, dan Laboratorium Uji Inderawi Fakultas Teknologi Pertanian Universitas Semarang. Metode penelitian adalah eksperimen dengan menggunakan Rancangan Percobaan Rancangan Acak Lengkap (RAL) dengan 1 faktor yaitu 5 perlakuan dan 4 kali ulangan variasi konsentrasi jahe merah, Penyayatan dengan cara menyayat tipis daging ayam kampung. Adapun perlakuan yang digunakan P0= 0% (tidak ada penambahan jahe merah atau 100% daging ayam kampung), P1= 2,5% (penambahan jahe merah sebanyak 2,5 g), P2= 5% (penambahan jahe merah sebanyak 5g), P3= 7,5% (penambahan jahe merah sebanyak 7,5g), P4= 10% (penambahan jahe merah sebanyak 10g), sedangkan parameter yang diamati adalah sifat fisik (tekstur), sifat kimia (kadar air, kadar protein, dan kadar lemak), dan sifat organoleptik ( warna). Apabila ada pengaruh yang nyata, maka diuji lanjut dengan menggunakan Tuckey taraf 5%. Konsentrasi jahe merah berpengaruh nyata (P<0,05) terhadap kadar air, kadar protein, tekstur (kekerasan) dan organoleptik (skor warna). Sedangkan terhadap kadar lemak tidak berbeda nyata. Panelis memilih P4 dengan skor warna 4,50 (coklat – coklat tua), dengan kadar air 6,38%, kadar lemak 0,20%, kadar protein 19,30% dan tekstur kekerasan 102,93 gf.
STUDENTS’ CRITICAL THINKING SKILLS DEVELOPMENT WITHIN PEDAGOGICAL SPECIALTIES OF MASTER'S EDUCATIONAL LEVEL IN THE CONTENT OF THE DISCIPLINE «PROFESSIONAL COMMUNICATION IN A FOREIGN LANGUAGE»
Authors: Kosharna Natalia
Published: June 2020

The article is devoted to the issue of studying the ways of developing students’ critical thinking skills within pedagogical specialties of master’s educational level in the content of the discipline «Professional communication in a foreign language». It was found out that the development of future teachers’ critical thinking skills directly depends on developing their communicative skills in the field of professional activity. It is pointed out the need to apply an integrated approach (language and professional) in mastering a foreign language professional communication (the English language), which allows future teachers to communicate in professional, pedagogical, social and personal spheres of activity; to develop a critical style of thinking. Its characteristics are flexibility, reflexivity, awareness of the internal ambiguity of positions and points of view, alternative decisions, formation the following basic personality traits as sociability, creativity, mobility, independence, responsibility for the personal choice, decision and the results of the teachers’ activities.
Pemberdayaan pada Penderita Diabetes Tipe 2 dan Kader Kesehatan dalam Pelaksanaan Program Pos Binaan Terpadu Penyakit Tidak Menular (Posbindu PTM)
Authors: Andriyanto Arief , Rekawati Etty , Rahmadiyah Dwi Cahya
Published: June 2020

Diabetes mellitus is classified as a non-communicable disease which has been estimated to have increased, so a risk factor control program recommended by the Ministry of Health is required according to the DM management pillar. Health cadre empowerment is also needed to actively support non-communicable diseases programs. The purpose of this community empowerment was to change the behaviour of people with type 2 diabetes in glucose control and improve the health cadres' skills in Posbindu PTM activities. The program was carried out in October 2018 until March 2019. The targets were: 86 type 2 diabetes patients, 24 cadres in Cisalak Pasar Kelurahan, 120 cadres in Cimanggis District, and 293 cadres in Depok City. The results showed that patients could control their glucose and health cadres experienced improved skills. The role of community nurses is continuously needed to provide appropriate interventions to the patients.
Derecho a la información en Coahuila: una perspectiva desde la justicia constitucional
Authors: Leal Espinoza José Luis
Published: June 2020

Los artículos 46, de la Ley de Acceso a la Información Pública y el 9, bis de la Ley de Notariado de Coahuila, establecen como sujetos obligados indirectos a los Notarios Públicos, en razón de que éstos llevan a cabo actos de autoridad. En el objetivo general se establecieron las pautas que el legislador determinó los criterios que se cumplieron en las obligaciones en materia de transparencia. Las razones expresadas en la resolución se expusieron a través de los métodos documental y cualitativo, bajo el cual el juez constitucional instructor del amparo indirecto 186/2016, establece que, contrario a lo expresado por el legislador, al notario no puede considerársele como sujeto obligado indirecto, toda vez que esta figura no encuadra en ningún supuesto relacionado con la coadyuvancia al auxilio o colaboración de las entidades públicas, ejercicio del gasto público, utilizar o disponer de recursos públicos, subsidios o estímulos fiscales, esta razón de forma es entendida en el sentido de que no recibe un sueldo del Estado.
Política de planeación de la educación superior en México e industria 4.0: 2013-2024
Authors: Cárdenas-Cabello Fernando
Published: June 2020

Este trabajo se fijó por objetivo observar, medir y contrastar la evolución de la importancia que se ha dado a la formación para la industria 4.0 en la educación superior, por parte del gobierno federal de México en las dos más recientes administraciones, tomando como fundamento el documento básico de planeación de cada una de estas, el PND (Pan Nacional de Desarrollo) 2013-2018, y el PND 2019-2024. Para identificar cómo ha evolucionado la importancia de la formación para la industria 4.0 en la educación superior, en la política de planeación del gobierno federal de México. El acercamiento teórico se realizó desde la perspectiva de estudio de las políticas públicas, mientras que el método recurrido para el estudio del objeto en cuestión fue el análisis de contenido. Se identificó una cualitativamente mayor importancia prestada a la formación superior para la industria 4.0 en PND más reciente. Se concluye que la política de planeación federal mexicana -desde su documento básico- en materia de educación superior, se ha ido adecuando cada vez más a las nuevas realidades tecnológicas de la sociedad.
Modelos de calidad aplicados al servicio de mediación en México
Authors: Guerrero-Vega Roberto N.
Published: June 2020

El presente artículo es una investigación que posee un enfoque meramente cualitativo, parte de un diseño no experimental, bajo un nivel documental-bibliográfico trasversal. Tiene por objetivo general analizar los principales modelos de evaluación de la calidad y definir cuál de ellos ha sido aplicado para evaluar el servicio de mediación en México. Tras la revisión de la literatura y el análisis documental se determinó que: Los principales modelos de calidad de índole nacional e internacional, aún no han sido aplicados para evaluar el servicio mediación, ya que están enfocados en evaluar un contexto general como lo es el sistema de justicia tradicional y otros rubros relacionados a la comercialización de productos y servicios. Sin embargo, se determinó que la calidad del servicio de mediación ha sido evaluada por modelos estandarizados, desarrollados por algunas investigaciones académicas. Se concluye que en México existe la necesidad de implementar modelos rigurosos y estandarizados encargados de evaluar al servicio de mediación, con la finalidad de obtener una certificación nacional e internacional que ratifique a las instituciones que cumplen con los estándares de calidad.
VISUAL CULTURE AND ITS CLOSE AFFILIATION WITH FEMINISM AND CRITICAL RACE THEORY
Authors: Sharma Sur
Published: June 2020

Visual culture attempts to expose that other facet of the world which almost hitherto remains concealed from the majority of the populace. This is because the people across the globe were fed with the visual images that largely went on a par with the interests of the white Europeans. In other words, visual culture views the world from a “subaltern” perspective and challenges the norms set by “a white European Christian male” centric outlook. To put it simply, visual culture studies and interprets the world, which is made up of visual images, from the point of view of marginalized, the suppressed or the disadvantaged. In this connection, the study of visual culture enjoys a close affiliation with feminism and critical race theory.
BANGLADESH-INDIA RELATIONS: TRENDS AND CHALLENGES
Authors: Alam Shah
Published: June 2020

The smooth relationship between Bangladesh and India is essential for these two neighboring countries as the relationship between the two countries is historical. The relations between the two countries are also highly significant for the international relations of South Asia.  The good relations between these countries originated since the liberation war of Bangladesh in 1971.  Seemingly, the good relations between them have been prevailing and continuing since the independence of Bangladesh. However, the relations between Bangladesh and India has been complicated and intricate. The historical legacies have often strained the relations between these two nations instead of cementing the bond through ancestral ties. The relations have been further complicated by the prolongation in resolving the disputable issues like waters sharing treaties, immigrant infiltrations, killings in the border, and so many. Hence, most of the Bangladeshi citizens believe that relations between Bangladesh and India are imbalanced. Thus, this paper argues that a combination of all these factors has, therefore, contributed to developing anti-Indian feelings among Bangladeshi citizens. This study aims to identify and explain the presence of such an antipathy towards India among Bangladeshi people. Upon exploring the underlying causes behind the anti-Indian sentiment among Bangladeshi citizens, the paper, finally, outlines some policy implications.
SCHOOL HEAD STRATEGIC MANAGEMENT IN DEVELOPING EDUCATION PROFESSIONALITY
Authors: Muntholib  , Hidayat  , Jaya
Published: June 2020

The Government has established qualifications and competency standards for education personnel, including Minister of Education Regulation No. 24/2008 concerning school administrative staff competencies, Minister of Education Regulation No.26/2008 concerning laboratories competence, Minister of Education Regulation No. 27/2008 concerning school counselor competencies. School education personnel who have met these standards can be said to be professional education staff. To meet these standards, principals must take special steps, hereinafter referred to as strategic management.

This study aims to determine and study the empirical picture of the strategic problems faced by Jambi City 1 High School, Muara Bungo 1 High School and Sungai Penuh City 1 and Sungai Penuh School and the strategy undertaken in responding to the needs of the development of education staff in the future to respond to global competition. This research uses a qualitative method with a descriptive approach, with data collection techniques using interviews, observation and document studies. Data analysis is performed through data display, data reduction and data verification processes.

The results of this study are generally the state of professionalism of the teaching staff in Jambi Province State Senior High School not all meet the standards set by the Government. The strategic management of the headmaster of SMA Negeri 1 in Jambi Province begins with a school self-evaluation. The results of the school self-evaluation serve as a reference for the school principal in the formulation of the school's vision, mission and goals as well as the principal's policy in developing professionalism of the teaching staff.