bluuebunny/crossref_metadata_2025 huggingface dataset:
Cognitive outcomes after unruptured intracranial aneurysm treatment with flow diversion
Authors: Wagner Kathryn , Srivatsan Aditya , Mohanty Alina , Srinivasan Visish M. , Saleem Yasir , Cherian Jacob , James Robert F. , Chen Stephen , Burkhardt Jan-Karl , Johnson Jeremiah , Kan Peter
Published: December 2019

OBJECTIVE

Flow diversion is increasingly used to treat a variety of intracranial aneurysms with good safety and efficacy; however, there is some evidence that this treatment is associated with a larger postoperative ischemic burden on imaging than that with other traditional endovascular modalities. These findings typically do not manifest as neurological deficits, but any subtle effects on cognition remain unknown. In this study, the authors describe the neurocognitive performance of a cohort of patients with unruptured intracranial aneurysms (UIAs) before and after treatment with flow diversion. This is the first report of cognitive outcomes following aneurysm treatment with flow diversion.

METHODS

The authors prospectively collected data on cognitive function using the Montreal Cognitive Assessment (MoCA) tool in patients with UIAs who were undergoing endovascular aneurysm treatment with flow diversion between June 2017 and July 2019. Patients completed the MoCA prior to intervention, at the 1-month follow-up after treatment, and again at 6 months after the procedure. All patients with UIAs treated with flow diversion were included regardless of age, aneurysm location, or morphology, unless their functional status precluded completion of the MoCA instrument. A repeated-measures linear mixed-effects model was used to compare preintervention and postintervention cognitive status at the time intervals outlined.

RESULTS

Fifty-one patients with 61 aneurysms underwent endovascular aneurysm treatment with flow diversion (mean age 52.5 years, 90.2% females). There was no difference between baseline and postprocedure MoCA scores at any time interval (p > 0.05). The MoCA scores at baseline, 1 month postprocedure, and 6 months postprocedure were 26.1, 26.2, and 26.6, respectively. There was also no difference between pre- and postprocedure scores on any individual domain of the instrument (visuospatial, naming, attention, language, abstraction, delayed recall, and orientation) at any time interval (p > 0.05). Thirty-four patients had follow-up MRI or CT imaging, 5 of whom showed radiographic changes or ischemia. All patients with follow-up clinical evaluation had a 6-month modified Rankin Scale score ≤ 2.

CONCLUSIONS

Flow diversion is increasingly used in the treatment of intracranial aneurysms. This study suggests that this treatment may not alter neurocognitive function. Larger patient samples and longer follow-ups with other tests of cognitive functions are needed to confirm these findings.
For the further training of individuals in neurosurgery II: the academic legacy of the William P. Van Wagenen Fellowship
Authors: Ormond D. Ryan , Abozeid Mohab , Kurpad Shekar , Haines Stephen J.
Published: December 2019

OBJECTIVE

William P. Van Wagenen pursued a research fellowship in Europe early in his career under the recommendation of Harvey Cushing. Later, Van Wagenen would be instrumental in the establishment of the William P. Van Wagenen Fellowship, a postgraduate fellowship for neurosurgeons from the AANS that requires study outside of a fellow’s country of residency training with plans to return to academic practice.

METHODS

Since 1968, 54 Van Wagenen Fellowships have been awarded, sending 54 fellows from 31 institutions to 13 different countries. The academic productivity of fellows was studied to determine the academic “return on investment” of the fellowship.

RESULTS

Almost all fellows have spent some time in academic neurosurgery (94%), with the vast majority remaining in academics for their entire career (87%); 52% of fellows have received NIH funding, and 55% have been promoted to professor. The numbers are even more striking for the first half of Van Wagenen Fellows (who received the fellowship from its inception in 1968 to 1994) with at least 25 years of career development who remained in academics: 65% received NIH funding, 86% were promoted to professor, and 62% became chairs of academic departments. The Hirsch index of fellows, defined as h papers from an individual with at least h citations, is higher than the national mean and median values for academic neurosurgeons at every academic rank. Fellows have served on national committees and as AANS and CNS presidents and have given back financially to the Neurosurgery Research and Education Foundation (NREF) to fund future research activities of neurosurgical residents and young faculty.

CONCLUSIONS

The Van Wagenen Fellowship will continue to provide young neurosurgeons with opportunities to pursue novel research and network with peers internationally and to motivate young neurosurgeons to transform neurosurgery. The legacy of Cushing and Van Wagenen continues today through the Van Wagenen Fellowship, a legacy that will only continue to grow.
Stimulated Raman histology for rapid and accurate intraoperative diagnosis of CNS tumors: prospective blinded study
Authors: Eichberg Daniel G. , Shah Ashish H. , Di Long , Semonche Alexa M. , Jimsheleishvili George , Luther Evan M. , Sarkiss Christopher A. , Levi Allan D. , Gultekin Sakir H. , Komotar Ricardo J. , Ivan Michael E.
Published: December 2019

OBJECTIVE

In some centers where brain tumor surgery is performed, the opportunity for expert intraoperative neuropathology consultation is lacking. Consequently, surgeons may not have access to the highest quality diagnostic histological data to inform surgical decision-making. Stimulated Raman histology (SRH) is a novel technology that allows for rapid acquisition of diagnostic histological images at the bedside.

METHODS

The authors performed a prospective blinded cohort study of 82 consecutive patients undergoing resection of CNS tumors to compare diagnostic time and accuracy of SRH simulation to the gold standard, i.e., frozen and permanent section diagnosis. Diagnostic accuracy was determined by concordance of SRH-simulated intraoperative pathology consultation with a blinded board-certified neuropathologist, with official frozen section and permanent section results.

RESULTS

Overall, the mean time to diagnosis was 30.5 ± 13.2 minutes faster (p < 0.0001) for SRH simulation than for frozen section, with similar diagnostic correlation: 91.5% (κ = 0.834, p < 0.0001) between SRH simulation and permanent section, and 91.5% between frozen and permanent section (κ = 0.894, p < 0.0001).

CONCLUSIONS

SRH-simulated intraoperative pathology consultation was significantly faster and equally accurate as frozen section.
Neuroendovascular-specific engineering modifications to the CorPath GRX Robotic System
Authors: Britz Gavin W. , Panesar Sandip S. , Falb Peter , Tomas Johnny , Desai Virendra , Lumsden Alan
Published: December 2019

OBJECTIVE

The aim of this study was to evaluate new, neuroendovascular-specific engineering and software modifications to the CorPath GRX Robotic System for their ability to support safer and more effective cranial neurovascular interventions in a preclinical model.

METHODS

Active device fixation (ADF) control software, permitting automated manipulation of the guidewire relative to the microcatheter, and a modified drive cassette suitable for neuroendovascular instruments were the respective software and hardware modifications to the current CorPath GRX robot, which was cleared by the FDA for percutaneous coronary and peripheral vascular intervention. The authors then trialed the modified system in a live porcine model with simulated neuroendovascular pathology. Femoral access through the aortic arch to the common carotid artery was accomplished manually (without robotic assistance), and the remaining endovascular procedures were performed with robotic assistance. The system was tested for the enhanced ability to navigate and manipulate neurovascular-specific guidewires and microcatheters. The authors specifically evaluated the movement of the wire forward and backward during the advancement of the microcatheter.

RESULTS

Navigation of the rete mirabile and an induced aneurysm within the common carotid artery were successful. The active device fixation feature enabled independent advancement and retraction of the guidewire and working device relative to the microcatheter. When ADF was inactive, the mean forward motion of the guidewire was 5 mm and backward motion was 0 mm. When ADF was active, the mean forward motion of the guidewire was 0 mm and backward motion was 1.5 mm. The modifications made to the robotic cassette enabled the system to successfully manipulate the microcatheter and guidewire safely and in a manner more suited to neuroendovascular procedures than before. There were no occurrences of dissection, extravasation, or thrombosis.

CONCLUSIONS

The robotic system was originally designed to navigate and manipulate devices for cardiac and peripheral vascular intervention. The current modifications described here improved its utility for the more delicate and tortuous neurovascular environment. This will set the stage for the development of a neurovascular-specific robot.
Spatial convergence of distant cortical regions during folding explains why arteries do not cross the sylvian fissure
Authors: Bush Alan , Nuñez Maximiliano , Brisbin Alyssa K. , Friedlander Robert M. , Goldschmidt Ezequiel
Published: December 2019

OBJECTIVE

Cortical folding places regions that are separated by a large distance along the cortical surface in close proximity. This process is not homogeneous; regions such as the insular opercula have a much higher cortical surface distance (CSD) to euclidean distance (ED) than others. Here the authors explore the hypothesis that in the folded brain the CSD, and not the ED, determines regions of common irrigation, because this measure corresponds more closely with the distance along the prefolded brain, where the subarachnoid arterial vascular network starts forming.

METHODS

The authors defined a convergence index that compared the ED to the CSD and applied it to the cortical surface reconstruction of an average brain. They then compared cortical convergence to the irrigation patterns of major sulci and fissures of the brain, by assessing whether these structures were crossed or not crossed by arterial vessels in 20 fixed hemispheres.

RESULTS

The regions of highest convergence (top 1%) were clustered around the sylvian fissure, which is the only brain depression with high convergence values along its edges. Arterial crossings were commonly observed in every major sulcus of the brain, with the exception of the sylvian fissure, constituting a highly significant difference (p < 10−4).

CONCLUSIONS

Arteries do not cross regions of high convergence. In the adult brain the CSD, rather than the ED, predicts the regional irrigation pattern. The distant origin of the frontal and temporal lobes creates a region of high cortical convergence, which explains why arteries do not cross the sylvian fissure.
Impact of master’s degree attainment upon academic career placement in neurosurgery
Authors: Khalafallah Adham M. , Jimenez Adrian E. , Tamargo Rafael J. , Witham Timothy , Huang Judy , Brem Henry , Mukherjee Debraj
Published: December 2019

OBJECTIVE

Previous authors have investigated many factors that predict an academic neurosurgical career over private practice, including attainment of a Doctor of Philosophy (PhD) and number of publications. Research has yet to demonstrate whether a master’s degree predicts an academic neurosurgical career. This study quantifies the association between obtaining a Master of Science (MS), Master of Public Health (MPH), or Master of Business Administration (MBA) degree and pursuing a career in academic neurosurgery.

METHODS

Public data on neurosurgeons who had graduated from Accreditation Council for Graduate Medical Education (ACGME)–accredited residency programs in the period from 1949 to 2019 were collected from residency and professional websites. Residency graduates with a PhD were excluded to isolate the effect of only having a master’s degree. A position was considered “academic” if it was affiliated with a hospital that had a neurosurgery residency program; other positions were considered nonacademic. Bivariate analyses were performed with Fisher’s exact test. Multivariate analysis was performed using a logistic regression model.

RESULTS

Within our database of neurosurgery residency alumni, there were 47 (4.1%) who held an MS degree, 31 (2.7%) who held an MPH, and 10 (0.9%) who held an MBA. In bivariate analyses, neurosurgeons with MS degrees were significantly more likely to pursue academic careers (OR 2.65, p = 0.0014, 95% CI 1.40–5.20), whereas neurosurgeons with an MPH (OR 1.41, p = 0.36, 95% CI 0.64–3.08) or an MBA (OR 1.00, p = 1.00, 95% CI 0.21–4.26) were not. In the multivariate analysis, an MS degree was independently associated with an academic career (OR 2.48, p = 0.0079, 95% CI 1.28–4.93). Moreover, postresidency h indices of 1 (OR 1.44, p = 0.048, 95% CI 1.00–2.07), 2–3 (OR 2.76, p = 2.01 × 10−8, 95% CI 1.94–3.94), and ≥ 4 (OR 4.88, p < 2.00 × 10−16, 95% CI 3.43–6.99) were all significantly associated with increased odds of pursuing an academic career. Notably, having between 1 and 11 months of protected research time was significantly associated with decreased odds of pursuing academic neurosurgery (OR 0.46, p = 0.049, 95% CI 0.21–0.98).

CONCLUSIONS

Neurosurgery residency graduates with MS degrees are more likely to pursue academic neurosurgical careers relative to their non-MS counterparts. Such findings may be used to help predict residency graduates’ future potential in academic neurosurgery.
Neurophysiological seizure-onset predictors of epilepsy surgery outcome: a multivariable analysis
Authors: Tanaka Hideaki , Gotman Jean , Khoo Hui Ming , Olivier André , Hall Jeffery , Dubeau François
Published: December 2019

OBJECTIVE

The authors sought to determine which neurophysiological seizure-onset features seen during scalp electroencephalography (EEG) and intracerebral EEG (iEEG) monitoring are predictors of postoperative outcome in a large series of patients with drug-resistant focal epilepsy who underwent resective surgery.

METHODS

The authors retrospectively analyzed the records of 75 consecutive patients with focal epilepsy, who first underwent scalp EEG and then iEEG (stereo-EEG) for presurgical assessment and who went on to undergo resective surgery between 2004 and 2015. To determine the independent prognostic factors from the neurophysiological scalp EEG and iEEG seizure-onset information, univariate and standard multivariable logistic regression analyses were used. Since scalp EEG and iEEG data were recorded at different times, the authors matched scalp seizures with intracerebral seizures for each patient using strict criteria.

RESULTS

A total of 3057 seizures were assessed. Forty-eight percent (36/75) of patients had a favorable outcome (Engel class I–II) after a minimum follow-up of at least 1 year. According to univariate analysis, a localized scalp EEG seizure onset (p < 0.001), a multilobar intracerebral seizure-onset zone (SOZ) (p < 0.001), and an extended SOZ (p = 0.001) were significantly associated with surgical outcome. According to multivariable analysis, the following two independent factors were found: 1) the ability of scalp EEG to localize the seizure onset was a predictor of a favorable postoperative outcome (OR 6.073, 95% CI 2.011–18.339, p = 0.001), and 2) a multilobar SOZ was a predictor of an unfavorable outcome (OR 0.076, 95% CI 0.009–0.663, p = 0.020).

CONCLUSIONS

The study findings show that localization at scalp seizure onset and a multilobar SOZ were strong predictors of surgical outcome. These predictors can help to select the better candidates for resective surgery.
Hyperoxemia during the hyperacute phase of aneurysmal subarachnoid hemorrhage is associated with delayed cerebral ischemia and poor outcome: a retrospective observational study
Authors: Fukuda Shinya , Koga Yasutaka , Fujita Motoki , Suehiro Eiichi , Kaneda Kotaro , Oda Yasutaka , Ishihara Hideyuki , Suzuki Michiyasu , Tsuruta Ryosuke
Published: December 2019

OBJECTIVE

The harmful effects of hyperoxemia have been reported in critically ill patients with various disorders, including those with brain injuries. However, the effect of hyperoxemia on aneurysmal subarachnoid hemorrhage (aSAH) patients is unclear. In this study the authors aimed to determine whether hyperoxemia during the hyperacute or acute phase in patients with aSAH is associated with delayed cerebral ischemia (DCI) and poor neurological outcome.

METHODS

In this single-center retrospective study, data from patients with aSAH treated between January 2011 and June 2017 were reviewed. The patients were classified into groups according to whether they experienced DCI (DCI group and non-DCI group) and whether they had a poor outcome at discharge (poor outcome group and favorable outcome group). The background characteristics and time-weighted average (TWA) PaO2 during the first 24 hours after arrival at the treatment facility (TWA24h-PaO2) and between the first 24 hours after arrival and day 6 (TWA6d-PaO2), the hyperacute and acute phases, respectively, were compared between the groups. Factors related to DCI and poor outcome were evaluated with logistic regression analyses.

RESULTS

Of 197 patients with aSAH, 42 patients experienced DCI and 82 patients had a poor outcome at discharge. TWA24h-PaO2 was significantly higher in the DCI group than in the non-DCI group (186 [141–213] vs 161 [138–192] mm Hg, p = 0.029) and in the poor outcome group than in the favorable outcome group (176 [154–205] vs 156 [136–188] mm Hg, p = 0.004). TWA6d-PaO2 did not differ significantly between the groups. Logistic regression analyses revealed that higher TWA24h-PaO2 was an independent risk factor for DCI (OR 1.09, 95% CI 1.01–1.17, p = 0.037) and poor outcome (OR 1.17, 95% CI 1.06–1.29, p = 0.002).

CONCLUSIONS

Hyperoxemia during the first 24 hours was associated with DCI and a poor outcome in patients with aSAH. Excessive oxygen therapy might have an adverse effect in the hyperacute phase of aSAH.
TÜRKİYE ‘DE YAŞAYAN GÖÇMEN SURİYELİ ANNELERİN ÇOCUK EĞİTİMİ YETERLİLİĞİ DÜZEYLERİNİN FARKLI DEĞİŞKENLER AÇISINDAN İNCELENMESİ
Authors: EMRE Oğuz , ULUTAŞ Ayşegül , AYANOĞLU Mine , KAÇMAZ Cihangir
Published: December 2019

Bir çocuğun gelişiminde çocuğun bulunduğu çevre ve aile faktörü önemli bir yere sahiptir. Çocuğun gelişiminde anne önemli yere sahiptir. Annelik ile ilgili olarak sorumlulukları uygun şekilde gerçekleştirme ve organize etme yeteneği ebeveyn yeterliliği olarak tanımlanmaktadır. Ebeveynin çocuğun bakım ve yetiştirilmesiyle ilgili sorumlulukları sahip olduğu kapasitesi, inançları yargıları ve kendi kültürüne göre değişiklik göstermektedir. Bu araştırmada çocuğu 5-12 yaş aralığında olan Türkiye ‘de yaşayan göçmen Suriyeli annelerin çocuk eğitimi yeterliliği düzeylerinin farklı değişkenler açısından incelenmesi amaçlanmıştır. Araştırmanın evrenini Mardin ilinde yaşayan Suriyeli anneler oluştururken, Türkçe okuryazar ve çalışmaya katılmaya istekli olan anneler içerisinden  seçkisiz örnekleme yöntemiyle seçilen 130 anne araştırmanın örneklemini oluşturmaktadır. Araştırmanın verileri "Genel Bilgi Formu" ve "Çocuk Eğitimi Yeterliliği Ölçeği (ÇEYÖ)" aracılığıyla toplanmıştır. Araştırmadan elde edilen veriler SPSS 24.0 paket programı ile değerlendirilmiş olup, verilerin analizinde tek yönlü varyans analizi (ANOVA) ve Tukey HSD testi kullanılmıştır. Araştırma sonuçları, annelerin çocuk eğitimi yeterliğinin annelerin yaşına ve çocuğun kaldığı kişilere göre farklılaşmadığını ortaya koymuştur. Anne eğitim durumu değişkenine göre çocuğu tanıma ve çocuğu yönlendirme alt boyut puan ortalamalarında ve çocuk sayısı değişkenine göre ise çocuğu geliştirme alt boyut puan ortalamalarında istatistiksel olarak anlamlı fark olduğu saptanmıştır (p<0,05).
Artem Medicalis – My ouroboros journey in art and science
Authors: Pollier Pascale
Published: December 2019

Artistic scientific research is, I believe, one of the ways out of the cul-de-sac that modern art brought us into during the latter part of the twentieth century. By returning to serious scientific and anatomical study, doors opened to a new discipline altogether. My personal journey as a medical artist took me from scientific wonder and intense interest in alchemy, through artistic anatomical research, on to functional medical illustration and back to conceptual art and sculpture. Having completed a course in forensic facial reconstruction I developed the idea of making a reconstruction of Andreas Vesalius’s face. Thus, began a quest to find the lost grave of the great anatomist. We have not found it yet but have already changed history.
Antonio Canova’s drawings in the Rare Books Collection of the Istituto Superiore di Sanità Library (Rome, Italy)
Authors: Toni Franco
Published: December 2019

The paper aims to promote the knowledge of the extraordinary collection of anatomical subject drawings by Antonio Canova, the most important Italian neoclassic artist, owned by the National Institute of Health Library in Rome. The history of acquisition by the library and the analysis of their importance in the long career of the artist is also treated. A short story about the fortune of the drawings in the last 20 years completes the study.
Exploring the interface between biomedical sciences and the arts through the global sci/art network MEDinART
Authors: Hatzi Vasia I
Published: December 2019

MEDinART (www.MEDinART.eu) is a continuously growing global sci/art network that connects biomedical sciences with technology and arts through the work of more than 170 artists from 30 countries who are influenced by aspects of biomedical sciences. MEDinART aims are to unite the artists who are influenced by biomedicine, to connect different countries and cultures through the universal language of sci/art, and to globalise the biomedical-inspired art movement. Inspired and created by the Author, Vasia Hatzi, MEDinART explores the interface between biomedicine with arts through talks, exhibitions and articles in events, conferences and journals around the world. Here we present the goals of MEDinARΤ, its philosophy and the messages that it delivers to society through its activities.
The need to bring creationist ideas to textbooks
Authors: Zhalko-Tytarenko V. , Lisovs’kyi A. , Rudyi B.
Published: December 2019

What is the relation of creationism to religion? Neither creationism nor evolutionism has a direct relation to religion, serving only as a basis for strengthening or weakening the positions of religion. Building a religion on this stand is a very separate thing. Therefore, it is not possible to criticize the proponents of reforming the textbooks of the "effort to disguise the discipleship of religion in the mind of the disciples," because then the symmetrical can be the proponents of the non-reformation - the "effort to disguise the atheism in the disciples' minds."
"Euroslam" - is it ridda or time consuming?
Authors: Hazyr-Ogly T.
Published: December 2019

Islam is now professed by the population of many countries in the Middle East, Asia, Africa, Europe. According to the World Islamic League, as of 2004, there were 1.2 billion Islamic followers in different countries (around 120 countries). In 35 countries, Muslims now make up 95-99 percent of the population, in 17 countries Islam is the state religion, and in 25 states, Muslims are an influential minority. Muslim communities are overwhelmed in Asia and North Africa. But they are also present in Europe, the US and Japan. According to statistics from the European Monitoring Center and Xenophobia (EUMC), Islam is the only religious religion in the world over the past 100 years, from 13 to 19.5 percent.
Dialogue between Muslims and Christians as part of the process of integrating Muslims into European society
Authors: Kyryushko M.I.
Published: December 2019

The presence of a large Muslim community in many European countries (most notably France, Germany, the United Kingdom, Italy, Spain), a growing role in the political processes of the Muslim population of Turkey, Albania, Macedonia, Bosnia and Herzegovina, the Kosovo region, the Kosovo region, and the Kosovo region. centers in European capitals, the emergence of international pan-European Muslim organizations attract the attention of researchers. The problem is whether modern Muslims are living in developed European countries as genuine Europeans, are they seeking full integration into European society, or are they looking to find themselves in a kind of new ghetto, delineated by the boundaries of religious and cultural differences.
Religious Paradigms of the Spirituality of Islam and Christianity in the Context of Ukraine's European Integration Processes
Authors: Kulagina-Stadnichenko Hanna M.
Published: December 2019

Recently, there has been increasing concern about the spiritual state of Ukrainian society. This problem has become much more relevant in view of Ukraine's European integration processes. The main factor underlying the quality of the latter are not the economic or even socio-political successes of the state. The question of extraordinary weight is the level of spirituality of the people of Ukraine, which must meet high international standards. In particular, this was discussed at the November 2005 Presidential Hearing.
Islam in the context of the political realities of Crimea
Authors: Kolodnyi Anatolii M.
Published: December 2019

Characteristic feature of the functioning of Islam as a religion in our time with its increasing globalization and politicization, increasing influences on the social life of many countries of its orthodox structures, manifestations of intolerance against the annoying. This is reflected in the following
World multiculturalism and the problem of tolerance (Islamic factor)
Authors: Vladychenko Larysa D. , Kyselov Oleh S.
Published: December 2019

Today, the world is a polycivilizational, multicultural, multinational, and polyreligious conglomerate. The process of globalization, which covered almost all spheres of human life, made it possible to increase the number of meetings of representatives of different national, cultural and religions of their identities. Actually, the future of all humanity depends on the nature of these meetings.
Development of communication science, computer science and cybernetics in the 1940s – 1950s
Authors: Kislov Denis
Published: December 2019

This publication presents the emergence of the new sciences that are most important for today’s world: communication science, cybernetics, the theory of information, and the theory of the noosphere in the 1940s – 1950s. The purpose of this article is to analyze the total scientific achievements in Eurasia at the time of the Second World War. This was a bright phenomenon in the formation of new revolutionary theories. Works of Chicago-based and Frankfurt-based schools of thought, the theoretical concepts of T. Adorno, M. Horkheimer, H. Lasswell, P. Lazarsfeld, аnd other researchers laid the foundations of the communication science and contributed to the breakthrough in a number of the key subject areas. A system approach to and a comparative analysis of the causes and subsequent consequences of the achievements at that time for today’s world served as a methodological basis for a comprehensive consideration of large-scale studies of the past. The scientific novelty of this historic study consists in the interdependence and complementarity of the theoretical and practical achievements in the 1940s and rethinking of their importance in the structure of concepts in the 20th century. Industrial and military goals associated with the automatic management and communication processes required fundamentally new approaches and achievements. When World War II broke out, N. Wiener worked on these problems aiming at creating a computer, which pushed him to the idea that the principles of managing biotic and abiotic systems are the same and to the cybernetic concept development. In the mid-1940s, J. von Neumann built the first digital computer. In 1945-1947, A. Turing worked, as an inventor of “a universal machine”, on the “electronic brain” project and was the first to develop a number of programs for it. In 1942, C. Shannon published his work dedicated to the theory of information permitting a constellation of researchers to lay the foundations of the theory of communication. V. Vernadsky’s noosphere concept proposed in 1944 was particularly important. At present, the ideas of that period are gaining new importance as a basis for the single planetary management system.
"Essay on the history of fossil ungulates" by Academician M. V. Pavlova as phenomenon in the world palaeozoological science (end of the nineteenth and early twentieth centuries)
Authors: Deforzh Hanna
Published: December 2019

The objective of the research is to reveal the main areas of research of Academician M. V. Pavlova in scientific works "Essay on the history of fossil ungulates" in the late nineteenth and early twentieth centuries, to show the contribution of these works to the world of palaeozoological science. The scientific novelty is that the life path and academic heritage of academician M. V. Pavlova was investigated in complex in the context of the development of Palaeozoology for the first time in Ukrainian historiography, and her scientific biography was reconstructed; the history of domestic palaeozoology is presented through the prism of M. V. Pavlova work and her scientific school; the published and handwritten works of the scientist were analyzed, which enabled to deepen the knowledge about the history of the national palaeozoological science and its influence on the development of world science. She demonstrated the importance of fossil mammal research for stratigraphic constructions. The founder of paleontology, as a scholarly discipline, is considered a prominent George Cuvier. Also, Paleontology and its section of Palaeozoology were created, such world-renowned scholars as Albert Godry, Otniel Marsh, Edward Cop, Volodymyr Kovalevsky, Melchior Neumire, Louis Dollo, Henry Osbourne, and others. To this galaxy of scientists-paleozoologist belongs also our compatriot, academician M. V. Pavlova (1854-1938). It was established that Maria Vasylivna Pavlova (in the girlhood M. V. Gortynskaya) is an entire era in the development of Palaeozoology. She is an outstanding specialist in the study of fossil mammals, the organizer and promoter of Palaeozoology Science. Maria Vasylivna is a world-class paleozoologist, a well-known specialist in scientific circles who was personally familiar with many prominent paleo scientists, for example, Albert Godri, who was her teacher at the Sorbonne, and with Henry Osborne she studied together at the same university, supported the connections with him all her life. The first woman-paleontologist, woman-professor, female academician in the Russian Empire, thanks to whom the domestic paleontology was allocated to independent biological science and which, with its research, laid the foundation for the development of paleontology (palaeozoology) in Ukraine. Works on the history of a large number of groups of fossil ungulates ended one of the cycles of M. V. Pavlova works, that showed the monophyletic development of most of the ungulates, the number of Tertiary and Quaternary faunas in the territory of the Russian Empire and in general in Ukraine.
The value of the Naturalists Society at Kharkiv University (1869-1930) in the development of scientific research and the popularization of scientific knowledge in Ukraine
Authors: Korobchenko Anhelina
Published: December 2019

The article reveals the importance of the Naturalists Society at Kharkiv University in the development of scientific research and the popularization of scientific knowledge in Ukraine. Social, economic, political processes that occur today in Ukraine actualize historical memory and direct historical science to comprehend the scientific processes that took place in Ukraine in ancient times. The reconstruction of scientific Ukraine in the second half of the 19th and early 20th centuries would be incomplete without an indication of the role and importance of the Naturalists Society at Kharkiv University. The author proves that the activity of the Society was versatile, large-scale, imbued with high scientific ideas and democratic tendencies. It is stated that the effectiveness of this activity was ensured by the active work of the most prominent figures of science, culture, education, namely: V. M. Arnoldi, P. I. Biletskyi, O. A. Hrosheim, O. V. Hurov, V. Ya. Danylevskyi, A. M. Krasnov, I. F. Levakovskyi, O. V. Nahornyi, O. M. Nikolskyi, Ya. V. Roll, M. M. Somov, P. P. Sushkin, V. I. Taliev, L. S. Tsenkovskyi, O. V. Chernaуa, V. O. Yaroshevskyi. In particular, the role of scientists in deployment of a wide range of floristic, faunistic, geological and geographical researches as in the territory of provinces of the Kharkov educational district, and it is far beyond its limits is shown. It is emphasized that thanks to the fruitful activity of members of society considerable scientific results which promoted the development of many branches of domestic natural sciences were received. It was a company with an effective organizational structure and program of activities; it achieved outstanding results both in applied research and in the popularization of science. The Society was one of the channels for ensuring the interconnection of science and society. It acted as a certain social institute, which envisaged conducting active communication activity both within the Society and beyond. Besides, training of future generations of scientists was carried out at a high level, which testified to another feature of the Society as a social institute and a phenomenon in the system of science. The author provides little-known information about the Society, specifies evaluations and conclusions, which relate to separate parts of the scientific and popularizing activity of the Society
PENDAMPINGAN IDENTIFIKASI PUSAKA BUDAYA DESA BALI AGA BELANDINGAN KINTAMANI BANGLI
Authors: Ambarwati Kardinal Ni G.A. Diah , Ketut Artatik I Gusti Ayu , Sarjana I Putu
Published: December 2019

Belandingan is the village of Bali Aga mountain type  located in Kintamani District, Bangli Regency, Bali. The location of Belandingan Village itself is quite secluded compared to other villages around Batur. Mount Batur was named the world geopark by UNESCO on 22 September 2013. Belandingan Village is included in 15 Batur Geopark Supporting villages. Although it has become a Supporting Village of Batur Geopark, there is not tourism planning done by the government. Research on the Village of Blandingan itself is difficult to find. The distinctive cultural richness of the Bali Aga  Village has the potential for the development of a heritage Tourism Village. The character of Belandingan Village community that is friendly and open to outsiders is also a potential in promoting the tourism of the village. Existing traditions are still in verbal version. The community has not been moved to document their culture. The people themselves when invited to discuss are less aware of the cultural uniqueness they have. For this reason, assistance was provided to the community in this case the religious leaders in the village of Belandingan  and Sekaa Teruna Teruni Mandala Cipta Belandingan Village to identify village heritage. It is hoped that the results of this identification will become written data and become material in promoting the field of tourism as a Bali Aga tourist village.
Tax incentives for innovation in the energy sector
Authors: Ivanova Olga , Laptiev Viacheslav
Published: December 2019

The article considers the current issues of stimulating innovation in the energy sector and rational use of energy resources. A three-level system of problem-oriented management of human resources for stimulating innovation in the energy sector is proposed. The system considers the impact of the human factor on innovative development at the national, regional and enterprise levels. Also, the need to encourage enterprises to hire highly qualified specialists in the sphere of energy saving and energy efficiency is proven. The role of the tax policy in state regulation of the rational use of energy resources and stimulation of innovation in the energy sector is substantiated. The tax incentives for the rational use of energy resources applied in the world practice are grouped. Features of the application of tax incentives (accelerated depreciation, tax credits, tax holidays, and tax reduction) for energy efficiency and energy saving of households and business entities are analyzed. Directions for stimulating innovation in the energy sector for the efficient use of energy resources are offered.
Efektivitas E-Learning Tingkat Sekolah Menengah Atas Kota Padang
Authors: Fransisca Monica , Yunus Yuliawati
Published: December 2019

The research is motivated by the problem of learning media from a number of schools in Padang that are not innovating in accordance with the development of the technological revolution even though the school facilities and infrastructure are sufficient for making technology-based learning media especially the Internet. The purpose of this study was to determine the effectiveness of the use of cloud computing learning media as a learning support media, in this case in the form of E-Learning. The population of this research was 71 high school students in Padang City with a sample of SMAN 4, 5 and 14 Padang. Based on the results of the calculation of effectiveness, the effectiveness level is classified as effective with an average percentage of 78.95%. So it can be concluded that the use of cloud computing as a learning support media is categorized as an effective media.
Implementasi Jaringan Hotspot Kampus Menggunakan Router Mikrotik
Authors: Mukti Yogi Isro
Published: December 2019

This research aims to implement the existing hotspot network on the campus of the Pagar Alam College of Technology by using a proxy router for the needs of all users, especially students and lecturers to support the academic process. This research is based on the existing internet network at the Pagar Alam College of Technology, which cannot be enjoyed entirely by students and lecturers on campus, because the internet network is only intended for the staff, LPPM room and multimedia lab room and the network lab room is only a few computers which is connected to the internet using a LAN cable. This study uses the method PPDIOO is prepare, plan, design, implement, operate, optimize network has been generated using a proxy router, starting with providing infrastructure, user management, bandwidth management and has been used by the academic community.
Zone Mapping at Marina Boom Banyuwangi Beach Based on Carrying Capacity Based on Sustainable Coastal Tourism
Authors: Amalia Firda Rachma , Sandi Enes Ariyanto , Febrian Ayu Wanda
Published: December 2019

Tourism activities are proliferating at the Marina Boom Beach, Banyuwangi, Indonesia. The concept relates to the creation of a balance between tourism activities and environmental sustainability, considering potential environmental damage caused by visitors. On the subject of supporting the fitting tourism management that may minimize the negative impact on environmental biophysical conditions, it is imperative to research tourism carrying capacity on the BOOM Beach tourism object. The method used in this research was a calculation based on the formula of Cifuentes (1992), which consists of Physical Carrying Capacity (PCC), Real Carrying Capacity (RCC), Effective Carrying Capacity (ECC), and Geographic Information (GIS). The results of this study showed that during 2016- 2018, over carrying capacity did not befall to tourists visiting Boom Beach Marina. Additionally, it was reported that among 100 travelers, the area preference was dispersed into 83% favoring park and the waterfront, 7% favoring dock, 5% favoring food court, 3% favoring stone bridge, and 2% favoring selfie spot in the old building. In the park area that covers 8,833 m 2, some calculations were conducted. The results showed the Physical Support Capacity (PCC) of 1,472 people, the Real Supporting Capacity (RCC) and the Effective Supporting Area (ECC) of 1,446 people, while in the Gandrung Sewu festival area an area of 10,938 m 2 is the Physical Support Capacity (PCC) of 1,823 people, the Real Supporting Capacity (RCC) and the Effective Supporting Capacity (ECC) of 1,791 people. In the future, this study may be a basis for further research in making strategic decisions for tourism development in Banyuwangi district.
Application of Entrepreneurship Model in Learning Practices to Improve the Ability to Teach Prospective Teachers
Authors: Setiani Ani , Bachri Asep Sjamsul , Novendra Afief Maula
Published: December 2019

This research is motivated by the inactivity of active learning for prospective teachers in improving the teaching ability of prospective teachers. This research was carried out in the Economic Education Study Program. The problem in this study is whether the Application of the Entrepreneurship Model in Learning Practices to improve the teaching ability of prospective students in the Economic Education Study Program. The research method used is the experimental method with a single group research design pre-test and post-test. The purpose of this study was to find out the difference in teaching ability of prospective student teachers at the initial measurement (pre-test) and after measurement (post test). The results of the study show that applying the Entrepreneurship Model in Learning Practices can contribute significantly to the teaching ability of prospective teachers. Statistically there is a difference between the values at pre-test and post-test. Based on the results of the study, to obtain more maximal results in improving the teaching ability of prospective teachers, it is recommended to apply the Entrepreneurship Model in Learning Practices in the study of the learning curriculum by paying attention to individual differences oriented to the teaching ability of professional teacher candidates, and making learning tools adapted to the development of technology and student needs.
Halal Awareness toward the Interest In Buying Foreign Food Product: A Case Study in Korean Instant Noodles Purchases by School teenagers in Jakarta
Authors: Hendradewi Savitri , Darsiah Anis , Mustika Amalia , Habibie Fachrul Husain
Published: December 2019

Good economic growth, a large population, and the majority of the population are Muslim, Indonesia is a lucrative market for marketing a product, so it is flooded with domestic and foreign products. Food products from abroad are much in demand by adolescents or school teenagers, so the adolescents need to be equipped with an awareness of the halalness of a food product. This study uses data analysis methods with validity and reliability, descriptive statistical analysis, Pearson correlation, and data collection techniques by distributing questionnaires to 100 school-aged respondents aged 15-21 located in Jakarta. Sampling using the Random Sampling method.  The stages of the research are surveying with questionnaires to: (i) identify and record the demographic characteristics of the respondents (ii) identify and register sources of information obtained about Korean products (iii) study and analyze halal awareness of the interests of purchasing foreign food products in adolescent school age 15- 21 years (iv)  analyze the influence of halal awareness on foreign food product purchase interests. The results of the research are: (i) Identification and registration of adolescent demographic characteristics (ii) Identification and  sources of information obtained about Korean products (iii) produce analysis of halal awareness of the interest in purchasing foreign food products  (iv) produce an analysis of the magnitude of the influence of halal awareness on the purchase of foreign food products in school teenagers aged 15-21 years.
Are Investor’s Splitting Orders ?: A Literature Studies
Authors: Syamni Ghazali , Nasir Nasir , Musnadi Said , Faisal Faisal
Published: December 2019

The purpose of this study is to analyses investor order splitting behavior in various exchanges market with a literature study approach. This study uses a literature study from various international journals and is reputable. The main finding of this study is that investors are reluctant to provide information to other investors. The behavior of investors who are reluctant to provide information to other investors is informed investors. Reluctance to provide information to other investors due to worry because the information is known by other investors so they cannot maintain the return that has been obtained from the superiority of information. So, to protect the information, informed investors break the trading orders they have into the size of intermediate trade.
Strategy Alternative in Developing Coffee Agribusiness: Study in Rengganis Mountain Slope Jember Regency in Indonesia
Authors: Kustiari Tanti , Afila Nila , Fillaili Ulfiana Sirtu
Published: December 2019

Coffee is one of the potential plantation products in Jember, East Java, Indonesia. The coffee production amount is mostly supported by the production amount in several regions at the Rengganis mountain slope. However, the coffee agribusiness potential in Rengganis mountain slope has not yet been optimized. Human resource and coffee institution are the two main elements in developing coffee agribusiness in Rengganis mountain slope, Jember. This study aims to choose the priority strategy as an effort in developing coffee agribusiness in Rengganis mountain slope, Jember by using Analytical Hierarchy Process (AHP). The result showed that the strategy in developing coffee agribusiness in Rengganis mountain slope is optimizing the function and role of the institution in making policy which supports the coffee agribusiness development through 3 institutions, namely: (1) government institution, (2) farmer organization, and (3) research institute.
Interaction Model Amongst Sport Event Image, E-Word of Mouth, Destination Image, Tourist Satisfaction and Loyalty in Traditional Bullrace in Tanah Datar Regency, West Sumatera
Authors: Lita Ratni Prima , Ma’ruf Ma’ruf
Published: December 2019

The aim of the paper is to investigate the interrelationship amongst sport event image, destination image, e-WOM, satisfaction and loyalty of spectator on the traditional bull racing sport in Tanah Datar regency, West Sumatra. Tourists who visited the bull race event in Tanah Datar participated as respondents. It involved both both local and foreign event spectators to Tanah Datar regency. A non-probability sampling method was used to recruit 145 respondents to respond to questionnaires. Stuctural Equation Modelling (SEM) was used to investigate the relationships among the research variables. The results show that sport event image has a positive and significant impact on the image of the destination and on the satisfaction of the tourists. Furthermore, e-WOM positively and significantly affects the destination image. The satisfaction of tourists also has a positive and significant impact on the loyalty of tourists. However, destination image variables have positive but not significant effect on the satisfaction of tourists at the bull race event in Tanah Datar regency, West Sumatra. Traditional sport event offers different value to the tourist, and the image of the destination play important role in the tourist decision to visit an event. Sport tourism not only about the event but also support from the interconnected aspect such as destination and level of satisfaction.