bluuebunny/crossref_metadata_2025 huggingface dataset:
Active control of dielectric singularities in indium-tin-oxides hyperbolic metamaterials
Authors: Pianelli Alessandro , Caligiuri Vincenzo , Dudek Michał , Kowerdziej Rafał , Chodorow Urszula , Sielezin Karol , De Luca Antonio , Caputo Roberto , Parka Janusz
Published: October 2022

Dielectric singularities (DSs) constitute one of the most exotic features occurring in the effective permittivity of artificial multilayers called hyperbolic metamaterials (HMMs). Associated to DSs, a rich phenomenology arises that justifies the ever-increasing interest profuse by the photonic community in achieving an active control of their properties. As an example, the possibility to “canalize” light down to the nanoscale as well as the capability of HMMs to interact with quantum emitters, placed in their proximity, enhancing their emission rate (Purcell effect), are worth mentioning. HMMs, however, suffer of an intrinsic lack of tunability of its DSs. Several architectures have been proposed to overcome this limit and, among them, the use of graphene outstands. Graphene-based HMMs recently shown outstanding canalization capabilities achieving λ/1660 light collimation. Despite the exceptional performances promised by these structures, stacking graphene/oxide multilayers is still an experimental challenge, especially envisioning electrical gating of all the graphene layers. In this paper, we propose a valid alternative in which indium-tin-oxide (ITO) is used as an electrically tunable metal. Here we have numerically designed and analyzed an ITO/SiO2based HMM with a tunable canalization wavelength within the range between 1.57 and 2.74 μm. The structure feature light confinement of λ/8.8 (resolution of about 178 nm), self-focusing of the light down to 0.26 μm and Purcell factor of approximately 700. The proposed HMM nanoarchitecture could be potentially used in many applications, such as ultra-fast signal processing, high harmonic generation, lab-on-a-chip nanodevices, bulk plasmonic waveguides in integrated photonic circuits and laser diode collimators.
Detection and categorization of severe cardiac disorders based solely on heart period measurements
Authors: Shinomoto Shigeru , Tsubo Yasuhiro , Marunaka Yoshinori
Published: October 2022

Cardiac disorders are common conditions associated with a high mortality rate. Due to their potential for causing serious symptoms, it is desirable to constantly monitor cardiac status using an accessible device such as a smartwatch. While electrocardiograms (ECGs) can make the detailed diagnosis of cardiac disorders, the examination is typically performed only once a year for each individual during health checkups, and it requires expert medical practitioners to make comprehensive judgments. Here we describe a newly developed automated system for alerting individuals about cardiac disorders solely by measuring a series of heart periods. For this purpose, we examined two metrics of heart rate variability (HRV) and analyzed 1-day ECG recordings of more than 1,000 subjects in total. We found that a metric of local variation was more efficient than conventional HRV metrics for alerting cardiac disorders, and furthermore, that a newly introduced metric of local-global variation resulted in superior capacity for discriminating between premature contraction and atrial fibrillation. Even with a 1-minute recording of heart periods, our new detection system had a diagnostic performance even better than that of the conventional analysis method applied to a 1-day recording.
Slope–temperature faceting diagram for macrosteps at equilibrium
Authors: Akutsu Noriko , Akutsu Yasuhiro
Published: October 2022

Faceting diagrams between surface slope and temperature are calculated numerically based on statistical mechanics for inclined surfaces between (001) and (111) surfaces at equilibrium. A lattice model is employed that includes point-contact-type step–step attractions from the quantum mechanical couplings between neighbouring steps. Comparing the obtained faceting diagrams with the phase diagram for step bunching proposed by Song and Mochrie for Si(113), the effective step–step attraction energy for Si(113) is approximately estimated to be 123 meV. The slope dependences of the mean height of the faceted macrosteps with a (111) side surface and that with a (001) side surface are calculated using the Monte Carlo method. The faceting diagrams can be used as a guide for controlling the assembling/disassembling of faceted macrosteps for designing new surface arrangements.
Integrative multiomic analyses of dorsal root ganglia in diabetic neuropathic pain using proteomics, phospho-proteomics, and metabolomics
Authors: Doty Megan , Yun Sijung , Wang Yan , Hu Minghan , Cassidy Margaret , Hall Bradford , Kulkarni Ashok B.
Published: October 2022

Diabetic peripheral neuropathy (DPN) is characterized by spontaneous pain in the extremities. Incidence of DPN continues to rise with the global diabetes epidemic. However, there remains a lack of safe, effective analgesics to control this chronic painful condition. Dorsal root ganglia (DRG) contain soma of sensory neurons and modulate sensory signal transduction into the central nervous system. In this study, we aimed to gain a deeper understanding of changes in molecular pathways in the DRG of DPN patients with chronic pain. We recently reported transcriptomic changes in the DRG with DPN. Here, we expand upon those results with integrated metabolomic, proteomic, and phospho-proteomic analyses to compare the molecular profiles of DRG from DPN donors and DRG from control donors without diabetes or chronic pain. Our analyses identified decreases of select amino acids and phospholipid metabolites in the DRG from DPN donors, which are important for cellular maintenance. Additionally, our analyses revealed changes suggestive of extracellular matrix (ECM) remodeling and altered mRNA processing. These results reveal new insights into changes in the molecular profiles associated with DPN.
Mitochondrial transporter expression patterns distinguish tumor from normal tissue and identify cancer subtypes with different survival and metabolism
Authors: Wohlrab Hartmut , Signoretti Sabina , Rameh Lucia E. , DeConti Derrick K. , Hansen Steen H.
Published: October 2022

Transporters of the inner mitochondrial membrane are essential to metabolism. We demonstrate that metabolism as represented by expression of genes encoding SLC25 transporters differentiates human cancers. Tumor to normal tissue expression ratios for clear cell renal cell carcinoma, colon adenocarcinoma, lung adenocarcinoma and breast invasive carcinoma were found to be highly significant. Affinity propagation trained on SLC25 gene expression patterns from 19 human cancer types (6825 TCGA samples) and normal tissues (2322 GTEx samples) was used to generate clusters. They differentiate cancers from normal tissues. They also indicate cancer subtypes with survivals distinct from the total patient population of the cancer type. Probing the kidney, colon, lung, and breast cancer clusters, subtype pairs of cancers were identified with distinct prognoses and differing in expression of protein coding genes from among 2080 metabolic enzymes assayed. We demonstrate that SLC25 expression clusters facilitate the identification of the tissue-of-origin, essential to efficacy of most cancer therapies, of CUPs (cancer-unknown-primary) known to have poor prognoses. Different cancer types within a single cluster have similar metabolic patterns and this raises the possibility that such cancers may respond similarly to existing and new anti-cancer therapies.
Stable iron isotopic composition of atmospheric aerosols: An overview
Authors: Wang Yuantao , Wu Libin , Hu Wei , Li Weijun , Shi Zongbo , Harrison Roy M. , Fu Pingqing
Published: October 2022

Atmospheric particulate matter (PM) has a significant impact on both the natural environment and human health. Iron is one of the most abundant elements in the earth’s crust, playing an important role in geochemical processes, and is also an important trace component in atmospheric PM. In recent years, with the rapid development of non-traditional (metal) stable isotope technologies, new solutions and methods for the source apportionments of heavy metal elements have been put forward. Stable iron isotope analysis has become an effective tool to trace iron in atmospheric particles. This review paper briefly summarizes the recent progress of atmospheric iron isotope geochemistry. We show that some of the major natural and anthropogenic PM sources have different iron isotopic compositions. A Bayesian isotopic mixing model MixSIAR was used to quantitatively re-evaluate the contributions of different sources to iron in both urban and marine aerosols based on iron isotopic data in the literature. The results highlight the value of stable iron isotope analyses as an effective tool in the source apportionment of atmospheric aerosols.
Functional orderly topography of brain networks associated with gene expression heterogeneity
Authors: Liu Wei , Zeng Ling-Li , Shen Hui , Zhou Zong-Tan , Hu Dewen
Published: October 2022

The human cerebral cortex is vastly expanded relative to nonhuman primates and rodents, leading to a functional orderly topography of brain networks. Here, we show that functional topography may be associated with gene expression heterogeneity. The neocortex exhibits greater heterogeneity in gene expression, with a lower expression of housekeeping genes, a longer mean path length, fewer clusters, and a lower degree of ordering in networks than archicortical and subcortical areas in human, rhesus macaque, and mouse brains. In particular, the cerebellar cortex displays greater heterogeneity in gene expression than cerebellar deep nuclei in the human brain, but not in the mouse brain, corresponding to the emergence of novel functions in the human cerebellar cortex. Moreover, the cortical areas with greater heterogeneity, primarily located in the multimodal association cortex, tend to express genes with higher evolutionary rates and exhibit a higher degree of functional connectivity measured by resting-state fMRI, implying that such a spatial distribution of gene expression may be shaped by evolution and is favourable for the specialization of higher cognitive functions. Together, the cross-species imaging and genetic findings may provide convergent evidence to support the association between the orderly topography of brain function networks and gene expression.
An exonuclease III-amplified 4-way strand migration system for low-abundance deletion mutation
Authors: Tang Xiaofeng , Li Qiaolin , Wang Juan , Liu Shanling
Published: October 2022

Exo III-amplified 4-way strand migration system for deletion mutation.
Sequence-complementarity dependent co-assembly of phosphodiester-linked aromatic donor–acceptor trimers
Authors: Appukutti Nadeema , de Vries Alex H. , Gudeangadi Prashant G. , Claringbold Bini R. , Garrett Michelle D. , Reithofer Michael R. , Serpell Christopher J.
Published: October 2022

Sequence-defined trimers of phosphodiester-linked aromatic donor–acceptors self-assemble according to monomer order, and co-assemble into new structures with their complementary sequence.
Fundamentals and applications of molecular photoelectron spectroscopy – Festschrift for Ivan Powis
Authors: Janssen Maurice , Nahon Laurent , Smirnova Olga , Stolow Albert
Published: October 2022

This themed collection includes a collection of articles on fundamentals and applications of molecular photoelectron spectroscopy.
Photocatalytic hydrogen evolution over Pt–Pd dual atom sites anchored on TiO2 nanosheets
Authors: Zhou Yaxin , Qin Hao , Fang Sihan , Wang Yangyang , Li Jun , Mele Giuseppe , Wang Chen
Published: October 2022

The defective TiO2 nanosheets (Vo-TiO2) supported dual atomic catalyst (Pt–Pd SAs/Vo-TiO2) to product hydrogen.
Database for liquid phase diffusion coefficients at infinite dilution at 298 K and matrix completion methods for their prediction
Authors: Großmann Oliver , Bellaire Daniel , Hayer Nicolas , Jirasek Fabian , Hasse Hans
Published: October 2022

We present new matrix completion methods for the prediction of binary liquid phase diffusion coefficients at infinite dilution, which are trained to a newly consolidated database in this work and outperform the established semiempirical correlations.
Modulation of the magnetic and photophysical properties in 3d–4f and 4f–4f′ heterobimetallic complexes involving a tetrathiafulvalene-based ligand
Authors: Douib Haiet , Flores Gonzalez Jessica , Speed Saskia , Montigaud Vincent , Lefeuvre Bertrand , Dorcet Vincent , Riobé François , Maury Olivier , Gouasmia Abdelkrim , Le Guennic Boris , Cador Olivier , Pointillart Fabrice
Published: October 2022

3d4f and 4f4f′ heterobimetallic complexes were designed thank to metal selective coordination with a redox-active tetrathiafulvalene-based ligand. Both magnetic and photophysical properties were investigated.
CuCoNi–S anchored CoMoO4/MoO3 forming core–shell structure for high-performance asymmetric supercapacitors
Authors: Li Tiansheng , Zhao Zhifeng , Su Zhanhua , Sun Rui , Li Xiaofeng , Shang Yongchen
Published: October 2022

CoMoO4/MoO3@CuCoNi–S is prepared by hydrothermal and electrodeposition methods. It offers promising supercapacitor properties.
Organosulphur, organoselenium and organotellurium compounds for the development of heterogeneous and nanocatalytic systems for Suzuki coupling
Authors: Arora Aayushi , Oswal Preeti , Sharma Deepali , Purohit Suraj , Tyagi Anupma , Sharma Pankaj , Kumar Arun
Published: October 2022

Heterogeneous and nanocatalytic systems have been developed using organosulphur, organoselenium and organotellurium ligands and their complexes, and they have been used to catalyze Suzuki coupling reaction.
The influence of saturation on the surface structure of mixed fatty acid-on-water aerosol: a molecular dynamics study
Authors: Stewart Aisling C. , Paterson Martin J. , Greaves Stuart J.
Published: October 2022

How ‘inert’ components affect the surface presence of reactive groups and overall structure of oleic acid-on-water aerosol: a computational study.
Co-intercalation-free ether electrolytes for graphitic anodes in lithium-ion batteries
Authors: Ma Peiyuan , Mirmira Priyadarshini , Eng Peter J. , Son Seoung-Bum , Bloom Ira D. , Filatov Alexander S. , Amanchukwu Chibueze V.
Published: October 2022

Fluorination of ether solvents suppresses solvent co-intercalation into graphite. The fluoroether electrolytes enable a wider working temperature window of Li-ion batteries and support silicon–graphite composite anodes.
Halogenated thiophenes serve as solvent additives in mediating morphology and achieving efficient organic solar cells
Authors: Guo Lingzhi , Li Qingduan , Ren Jiaxuan , Xu Yuanjie , Zhang Jiabin , Zhang Kai , Cai Yuepeng , Liu Shengjian , Huang Fei
Published: October 2022

Halogenated thiophene (FBrT) dissolves donor and acceptor readily, providing meaningful roles in mediating morphology. Thus, FBrT possesses general applicability in reaching efficient organic solar cells with improved fill factors and efficiencies.
Determination of contaminants of emerging concern in raw pig manure as a whole: difference with the analysis of solid and liquid phases separately
Authors: Portela-Monge Cristina , Bolado Silvia , López-Serna Rebeca , Jiménez Juan José
Published: October 2022

The determination of the total amount of CECs in raw manure as a whole seems an advisable option compared to the analysis of the phases separately. The determination of the amounts of CECs contained in the liquid phase could be underestimated.
Synthesis and characterization of a novel slow-release nanourea/chitosan nanocomposite and its effect on Vigna radiata L.
Authors: Sharma Avimanu , Kumar Sanjeev , Singh Ritu
Published: October 2022

The efficiency of chitosan coated nanourea as a slow release fertilizer was investigated and compared with commercial urea. The coated nanourea significantly enhanced soil properties, improved plant growth and reduced nitrate leaching.
Cyclo-(Phe-Tyr) reduces cerebral ischemia/reperfusion-induced blood–brain barrier dysfunction through regulation of autophagy
Authors: Liang Jiayin , Cai Jiale , Zhang Yutong , Xie Meixia , Li Xiaoshi , Hu Tao , Liang Shengwang , Xian Minghua , Wang Shumei
Published: October 2022

Cerebral ischemia/reperfusion (I/R) injury is the result of an ischemic stroke, a serious threat to public health. I/R injury can damage the blood–brain barrier (BBB), adversely affecting the brain environment and aggravating the injury.
Deep learning detector for high precision monitoring of cell encapsulation statistics in microfluidic droplets
Authors: Gardner Karl , Uddin Md Mezbah , Tran Linh , Pham Thanh , Vanapalli Siva , Li Wei
Published: October 2022

A dual model object detection system for high precision monitoring of cell encapsulation statistics in microfluidic droplets with comparisons from YOLOv3 and YOLOv5 performance.
Bioprinting-based automated deposition of single cancer cell spheroids into oxygen sensor microelectrode wells
Authors: Dornhof Johannes , Zieger Viktoria , Kieninger Jochen , Frejek Daniel , Zengerle Roland , Urban Gerald A. , Kartmann Sabrina , Weltin Andreas
Published: October 2022

With an advanced bioprinter, we print cancer cell spheroids directly into chip-based oxygen microsensors to determine single spheroid metabolism and drug responses.
Process optimisation for NASICON-type solid electrolyte synthesis using a combination of experiments and bayesian optimisation
Authors: Takeda Hayami , Fukuda Hiroko , Nakano Koki , Hashimura Syogo , Tanibata Naoto , Nakayama Masanobu , Ono Yasuharu , Natori Takaaki
Published: October 2022

The optimal sintering conditions for LiZr2(PO4)3, a NASICON-type solid electrolyte with high conductivity, were explored. It was also found that these optimum sintering conditions could be efficiently discovered by using Bayesian optimisation.
Complex amorphous oxides: property prediction from high throughput DFT and AI for new material search
Authors: van Setten Michiel J. , Dekkers Hendrik F. W. , Pashartis Christopher , Chasin Adrian , Belmonte Attilio , Delhougne Romain , Kar Gouri S. , Pourtois Geoffrey
Published: October 2022

To search for the next semiconductor breakthrough, we calculate properties for binary amorphous systems and model to predict them for complex compositions.
Flexible electrochromic devices having remarkable color change from golden to green and their application in smart windows and electronic labels
Authors: Guo Xu , Wang Peng , Qian Chao , Jiang Chuanyu , Liu Ping
Published: October 2022

The ECDs based on viologen derivatives exhibit high optical contrast, fast-response, and rich color changes.
Nitridation of Cr–urea complex into nanocrystalline CrN and its antiferromagnetic magnetostructural transition study
Authors: Singh Dadan , Tamrakar Saumya , Shrivas Kamlesh , Dewangan Khemchand
Published: October 2022

An antiferromagnetic nanocrystalline CrN interstitial compound was prepared using Cr(NO3)3·9H2O and urea as starting materials.
Towards an understanding of the biological activity of naphthylisoquinoline alkaloids: DNA-binding properties of dioncophyllines A, B, and C
Authors: Soost Denisa , Bringmann Gerhard , Ihmels Heiko
Published: October 2022

Dioncophylline A and B bind to duplex DNA in a half-intercalation binding mode and to abasic site-containing DNA by insertion.
Ruthenium-based antitumor drugs and delivery systems from monotherapy to combination therapy
Authors: Lu Yu , Zhu Di , Le Quynh , Wang Yuji , Wang Wei
Published: October 2022

The applications of ruthenium antitumor drugs and delivery systems are developing from single chemotherapy to combination therapy.
Self-standing Fe3O4 decorated paper electrode as a binder-free trifunctional electrode for electrochemical ammonia synthesis and Zn–O2 batteries
Authors: Kafle Alankar , Gupta Divyani , Bordoloi Ankur , Nagaiah Tharamani C.
Published: October 2022

Self-standing Fe3O4 decorated paper electrode shows remarkable electrocatalytic activity towards ammonia production as well as Zn–O2 batteries eliminating the additional power supply for the production ammonia via electrochemical approach.
Synthesis of N-substituted quaternary carbon centers through KOt-Bu-catalyzed aza-Michael addition of pyrazoles to cyclic enones
Authors: Yoon Subin , Lee Sungbin , Nam Seung Hyun , Lee Hyejeong , Lee Yunmi
Published: October 2022

This study reports an effective and mild protocol for the construction of N-substituted quaternary carbon centers via the KOt-Bu-catalyzed aza-Michael addition of pyrazoles with β-substituted cyclic enones.
Reverse sequence polymerization-induced self-assembly in aqueous media: a counter-intuitive approach to sterically-stabilized diblock copolymer nano-objects
Authors: Penfold Nicholas J. W. , Neal Thomas J. , Plait Corentin , Leigh Andrew E. , Chimonides Gwen , Smallridge Mark J. , Armes Steven P.
Published: October 2022

A 500 nm charge-stabilized latex is converted into 40 nm sterically-stabilized nanoparticles via reverse sequence polymerization-induced self-assembly (PISA).
Recent advances and future prospects of functional organ-on-a-chip systems
Authors: Salehi Moghaddam Abolfazl , Salehi Moghaddam Zahra , Davachi Seyed Mohammad , Sarikhani Einolah , Nemati Mahand Saba , Khonakdar Hossein Ali , Bagher Zohreh , Ashammakhi Nureddin
Published: October 2022

The pressing demand for a creative method to effectively model human drug responses in preclinical research has prompted the advancement of organ-on-a-chip (OoC) systems.
Highly efficient solar-absorber composite material based on tetrapyridylporphyrin for water evaporation and thermoelectric power generation
Authors: Zhang Yifeng , Yan Hanbing , Wang Xuefeng , Zhang Zhenyu , Liu Fengchun , Tu Shan , Chen Xiufang
Published: October 2022

Photothermal conversion materials based on tetrapyridylporphyrin (TPyP) were studied and were found to possess a polypyrrole macrocyclic framework (18π electrons), which makes them exhibit strong absorption in the 300–800 nm region and high photothermal conversion.
Critical current density improvement in CSD-grown high-entropy REBa2Cu3O7−δ films
Authors: Cayado Pablo , Grünewald Lukas , Erbe Manuela , Hänisch Jens , Gerthsen Dagmar , Holzapfel Bernhard
Published: October 2022

High-resolution STEM-EDXS chemical analysis of (a) medium-entropy and (b) high-entropy REBCO films grown on SrTiO3. The RE signals are homogeneously distributed in the films.
Hybrid Tamm plasmon resonance excitation towards a simple and efficient biomedical detector of NaI solution
Authors: Taha T. A. , Elsayed Hussein A. , Mehaney Ahmed , Hajjiah Ali , Ahmed Ashour M.
Published: October 2022

NaI sensor: the suggested design of a NaI photonic crystal sensor that is constituted.
Exploration of the interesting photovoltaic behavior of the fused benzothiophene dioxide moiety as a core donor with modification in acceptors for high-efficacy organic solar cells
Authors: Khalid Muhammad , Anwer Wajeeha , Adeel Muhammad , Shafiq Zahid , Braga Ataualpa A. C. , Assiri Mohammed A. , Imran Muhammad , Ullah Aman
Published: October 2022

Non-fullerene-based chromophores with end-capped acceptor modification used in organic solar cells (OSCs) have proven to offer improved performance.
KMnCuTe2: a layered antiferromagnetic semiconductor with long metal–metal distance
Authors: Sun Fan , Liu Zhao , Lin Jiawei , Deng Jun , Guo Zhongnan , Yuan Wenxia
Published: October 2022

We synthesized a new quaternary telluride KMnCuTe2 with long metal–metal distance in tetragonal layers, which shows an indirect band gap of 0.95 eV and long-range antiferromagnetic ordering.
The effect of thermodynamic changes in the cooling of saline soils on the corrosion system of carbon steels
Authors: Qi Gang , Dong Yanli , Feng Yongxiang , Wei Jianjian , Han Pengju , Bai Xiaohong , He Bin
Published: October 2022

The corrosion behavior and mechanism of carbon steels during cooling to a freezing state in natural saline soil were studied by an electrochemical test.
Electrocatalytic water oxidation on CuO–Cu2O modulated cobalt-manganese layered double hydroxide
Authors: Hameed Arslan , Zulfiqar Faiza , Iqbal Waheed , Ali Hassan , Ahmad Shah Syed Shoaib , Nadeem Muhammad Arif
Published: October 2022

Layered double hydroxides (LDH) have potential to catalyze the sluggish oxygen evolution reaction.
Aqueous Suzuki couplings mediated by a hydrophobic catalyst
Authors: Hong Sheng-Bo , Liang Lan-Chang
Published: October 2022

Though hydrophobic, the amido PNP complex [(Ph2P-o-C6H4)2N]PdCl is a competent catalyst in aqueous Suzuki couplings under aerobic conditions without the necessity of amphiphiles even in the presence of an excess amount of mercury.
Nanostructured IrOx supported on N-doped TiO2 as an efficient electrocatalyst towards acidic oxygen evolution reaction
Authors: Li Guoqiang , Jia Hongrui , Liu Huan , Yang Xin , Lin Meng-Chang
Published: October 2022

N–TiO2 is synthesized and innovatively employed to support IrOx nanoparticles for boosting the OER catalytic activity, stability and catalyst utilization.
Water-phase synthesis of Au and Au–Ag nanowires and their SERS activity
Authors: Kichijo Ryota , Miyajima Naoya , Ogawa Daisuke , Sugimori Hirokazu , Wang Ke-Hsuan , Imura Yoshiro , Kawai Takeshi
Published: October 2022

The solubilizing organic solvents play an important role in controlling the morphology of Au nanowires, and solubilizing methylcyclohexane and toluene yield thick 2.7 nm-diameter and thin 1.8 nm-diameter Au nanowires.
Decorating MnO2 nanosheets on MOF-derived Co3O4 as a battery-type electrode for hybrid supercapacitors
Authors: Babu S. Kishore , Gunasekaran B. , Sridharan M. , Vijayakumar T.
Published: October 2022

Metal–organic framework-derived materials are now considered potential next-generation electrode materials for supercapacitors.
Engineering hydrogen bonding to align molecular dipoles in organic solids for efficient second harmonic generation
Authors: Zhao Ruyan , Zhu Tong , Wang Sasa , Jarrett-Wilkins Charlie , Najjarian Amin Morteza , Lough Alan J. , Hoogland Sjoerd , Sargent Edward H. , Seferos Dwight S.
Published: October 2022

We switch the molecule from SHG inert to SHG active by controlling the degree of hydrogen bonding through protonation.
Linoleic acid metabolism activation in macrophages promotes the clearing of intracellular Staphylococcus aureus
Authors: Yan Bingpeng , Fung Kingchun , Ye Sen , Lai Pok-Man , Wei Yuan Xin , Sze Kong-Hung , Yang Dan , Gao Peng , Kao Richard Yi-Tsun
Published: October 2022

Infected macrophages release signaling lipids (e.g., linoleic acid) and activate subsequent metabolic pathways to stimulate ROS generation that facilities intracellular bacteria killing, which may represent a novel mechanism of bacterial elimination.
Super-resolved dynamics of isolated zinc formation during extremely fast electrochemical deposition/dissolution processes
Authors: Mao Jiaxin , Li Guopeng , Saqib Muhammad , Xu Jiantie , Hao Rui
Published: October 2022

The isolated zinc (i-Zn) formation in extremely high-rate batteries is studied with combinedin situsuper-resolution imaging and electrochemical analysis. Nanoscopic i-Zn forms and converts to excess passivated products increasing the overpotential.
Facile synthesis and characterization of γ-Al2O3 loaded on reduced graphene oxide for electrochemical reduction of CO2
Authors: Mulik Balaji B. , Bankar Balasaheb D. , Munde Ajay V. , Biradar Ankush V. , Asefa Tewodros , Sathe Bhaskar R.
Published: October 2022

Electrocatalytic reduction of CO2 to valuable organic compounds and fuels using energy efficient techniques is presently of great importance. In this work, we report Al2O3-decorated reduced graphene oxide electrocatalysts for the conversion of CO2 into formate.
Growing COFsin situon CdS nanorods as core–shell heterojunctions to improve the charge separation efficiency
Authors: Feng Yanan , Li Jingjun , Ye Shihua , Gao Shuiying , Cao Rong
Published: October 2022

A Z-scheme heterojunction CdS@TTI-COF with a core–shell structure was prepared for efficient photocatalytic hydrogen evolution.
AGE-breaker ALT711 reverses glycation-mediated cancer cell migration
Authors: Rowe Matthew M. , Wang Wenjun , Taufalele Paul V. , Reinhart-King Cynthia A.
Published: October 2022

High glucose causes accelerated production of AGE crosslinks within extracellular matrices. ALT711 treatment can reduce AGEs in collagen I hydrogels to impact breast cancer cell migration.
Dependence of thermoelectric effects in molecular junctions on the topography of the bottom electrodes
Authors: Peng Wuxian , Cao Zhou , Chen Ningyue , Xie Yu , Li Yuan
Published: October 2022

The values of the Seebeck coefficient and power factor of a molecular junction can be regulated by the topography of the electrode.
Spherical-micelle-driven deposition of high-speed impacting water droplets on superhydrophobic surfaces
Authors: Jiang Yue , Wang Meina , Wei Jinchao , Fan Yaxun , Wang Yilin
Published: October 2022

This work utilizes modified small spherical micelles of surfactants to achieve complete deposition of high-speed impacting water droplets on superhydrophobic surfaces, without the assistance of high viscosity, low surface tension or large aggregates.
Regular hexagonal CuBi nanosheets boost highly efficient CO2reduction to HCOOH in a solid-electrolyte cell
Authors: Wang Xiaoshan , Fei Xiang , Wang Mingwang , Wang Wenhang , Yang Zhongxue , Ning Hui , Zhang Yunlong , Wang Li , Jin Xin , Wu Mingbo
Published: October 2022

The electrochemical carbon dioxide reduction reaction (CRR) to formic acid has shown great potential in carbon capture, utilization and storage (CCUS).
Biobased polymer resources and essential oils: a green combination for antibacterial applications
Authors: Elian Christine , Andaloussi Samir Abbad , Moilleron Régis , Decousser Jean-Winoc , Boyer Cyrille , Versace Davy-Louis
Published: October 2022

Essential oils (EOs) can act as natural biocide agents when introduced in renewable/bio-based polymers. The nature of EOs influences the mechanical properties and the antibacterial activities of the final bio-based materials.
Synapse transistors based on Li7La3Zr2O12 (LLZO) nanofibers/polyvinyl alcohol (PVA) composite gate dielectric for neuromorphic application
Authors: Lei Yuxing , Li Jun , Fu Wenhui , Zhang Jianhua
Published: October 2022

A synapse transistor based on LLZO nanofibers/PVA composite dielectric with nanofibers providing an ionic conductive pathway shows a large PPF index at low frequency, which is a positive exploration to achieve high performance synapse transistors.
Green synthesis of SrO nanoparticles using leaf extract of Albizia julibrissin and its recyclable photocatalytic activity: an eco-friendly approach for treatment of industrial wastewater
Authors: Shimi Annin K. , Parvathiraj C. , Kumari Suman , Dalal Jasvir , Kumar Vipan , Wabaidur Saikh M. , Alothman Zeid A.
Published: October 2022

The present work unveils the reusable photocatalytic action of strontium oxide (SrO) nanoparticles synthesized using Albizia julibrissin plant extract via the co-precipitation method.
What Is “Music” in Music-to-Language Transfer? Musical Ability But Not Musicianship Supports Cantonese Listeners' English Stress Perception
Authors: Choi William
Published: October 2022

Purpose:

This study investigates how Cantonese language experience influences the potential effects of (a) musicianship and (b) musical ability on English stress perception.

Method:

The sample contained 124 participants, evenly split into Cantonese musician, Cantonese nonmusician, English musician, and English nonmusician groups. They completed the English stress discrimination task, English stress sequence recall task, Musical Ear Test, and nonverbal intelligence task. Following the musicianship-based analysis, 44 Cantonese and English listeners were reassigned to four groups based on their musical ability—Cantonese high musical ability, Cantonese low musical ability, English high musical ability, and English low musical ability groups.

Results:

Musicianship-based analysis on English stress perception revealed a significant interaction between musicianship and language. Specifically, musicians outperformed nonmusicians only among the English but not the Cantonese listeners. By contrast, ability-based analysis showed significant main effects of musical ability and language. For both Cantonese and English listeners, those with a high musical ability outperformed those with a low musical ability. Regardless of musical ability, Cantonese listeners outperformed English listeners. Correlational analyses yielded consistent findings.

Conclusions:

This study has found cross-sectional evidence that musical ability, but not musicianship, facilitates Cantonese English as a second language (ESL) listeners' English stress perception. From a theoretical perspective, the current findings motivate two potential additions to the OPERA (Overlap, Precision, Emotion, Repetition, and Attention) hypothesis for music-to-language transfer—unsaturation and utilization. Practically, the findings cast doubt on the application of nonperceptual based instrumental music training to enhance Cantonese ESL learners' perceptual learning of English stress.

Supplemental Material:

https://doi.org/10.23641/asha.21266478
CP‐SyNet: A tool for generating customised cyber‐power synthetic network for distribution systems with distributed energy resources
Authors: Wang Lusha , Halvorsen James , Pannala Sanjeev , Srivastava Anurag , Gebremedhin Assefaw H. , Schulz Noel N.
Published: October 2022

The integration of distributed energy resources and advancement in information technology has enabled the transition of traditional power distribution systems to active cyber‐physical distribution systems. A growing amount of research has been done on the modelling, analysis, and optimisation of power distribution system behaviour. However, existing publicly available distribution test feeders are limited in numbers and have minimal features. Furthermore, these test feeders do not include cyber models and are not customisable. To bridge this gap, we propose and develop Cyber‐physical synthetic distribution system network (CP‐SyNet), a tool for generating customisable cyber‐physical synthetic distribution test feeders. CP‐SyNet generates three‐phase unbalanced test feeders according to users' requirements, while simultaneously considering both the cyber side and the physical side of the network for cyber‐physical analysis. The physical test network is developed using a graph‐theoretical approach that employs information from existing test feeders. The cyber side considers an equivalent communication network by transforming the physical topology into possible and feasible simulated network. Two examples are presented to demonstrate the feasibility of the proposed framework to generate cyber‐physical test feeders.
Astrocytes réactifs et maladies cérébrales
Authors: Poulot-Becq-Giraudon Yiannis , Carrillo-de Sauvage Maria-Angeles , Escartin Carole
Published: October 2022

Les astrocytes sont des partenaires essentiels des neurones dans le système nerveux central. En réponse à de nombreuses maladies qui touchent le cerveau, les astrocytes subissent des modifications morphologiques, moléculaires et fonctionnelles : ils deviennent réactifs. Ces changements multiples sont susceptibles d’avoir un impact important sur les neurones, qui dépendent de nombreuses fonctions remplies par les astrocytes. La réponse de réactivité astrocytaire dépend du contexte pathologique. Il est donc indispensable de définir précisément les changements qui se produisent dans les astrocytes réactifs dans chaque situation pathologique, par des approches adaptées et sélectives. Cela permettra le développement de thérapies innovantes ciblant ces cellules partenaires des neurones, ainsi que l’identification de biomarqueurs spécifiques de certaines maladies cérébrales.
Mixed Reality in der Gefäßchirurgie – ein Scoping Review
Authors: Hatzl Johannes , Böckler Dittmar , Meisenbacher Katrin , Barb Alexandru , Hartmann Niklas , Henning Daniel , Uhl Christian
Published: October 2022

Hintergrund „Mixed Reality“ (MR) erlaubt die Projektion von virtuellen Objekten in das Sichtfeld des Anwenders durch ein Head-mounted Display (HMD). Im gefäßchirurgischen
Behandlungsspektrum könnten MR-Anwendungen in Zukunft einen Nutzen darstellen. Im folgenden Scoping Review soll eine Orientierung über die aktuelle Anwendung der genannten Technologien im
Bereich der Gefäßchirurgie gegeben und Forschungsziele für die Zukunft definiert werden. Material und Methoden Es erfolgte eine systematische Literaturrecherche in PubMed (MEDLINE)
mit den Suchbegriffen „aorta“, „intervention“, „endovsacular intervention“, „vascular surgery“, „aneurysm“, „endovascular“, „vascular access“ jeweils in Kombination mit „mixed reality“ oder
„augmented reality“. Die Suche erfolgte nach PRISMA-Leitlinie (Preferred Reporting Items for Systematic reviews and Meta-Analyses) für Scoping Reviews. Ergebnisse Aus 547
Literaturstellen konnten 8 relevante Studien identifiziert werden. Die Suchergebnisse konnten in 2 Anwendungskategorien eingeteilt werden: (1) MR mit dem Ziel des Informationsmanagements und
zur Verbesserung der periprozeduralen Ergonomie gefäßchirurgischer Eingriffe (n = 3) sowie (2) MR mit dem Ziel der intraoperativen Navigation bei gefäßchirurgischen Eingriffen (n = 5). Die
Registrierung des physischen Patienten mit dem virtuellen Objekt und das Tracking von Instrumenten in der MR-Umgebung zur intraoperativen Navigation ist dabei im Fokus des wissenschaftlichen
Interesses und konnte technisch erfolgreich am Phantom- und Tiermodell gezeigt werden. Die bisher vorgestellten Methoden sind jedoch mit hohem infrastrukturellem Aufwand und relevanten
Limitationen verbunden. Schlussfolgerung Der Einsatz von MR im Bereich der Gefäßchirurgie ist grundsätzlich vielversprechend. Für die Zukunft sollten alternative, pragmatische
Registrierungsmethoden mit entsprechender Quantifizierung des Positionierungsfehlers angestrebt werden. Die entwickelten Soft- und Hardwarelösungen sollten auf das Anforderungsprofil der
Gefäßchirurgie angepasst werden. Das elektromagnetische Instrumenten-Tracking erscheint als sinnvolle, komplementäre Technologie zur Umsetzung der MR-assistierten Navigation.
Phenotyping, Precision Medicine, and Asthma
Authors: Mohan Arjun , Lugogo Njira L.
Published: October 2022

The traditional one-size-fits all approach based on asthma severity is archaic. Asthma is a heterogenous syndrome rather than a single disease entity. Studies evaluating observable characteristics called phenotypes have elucidated this heterogeneity. Asthma clusters demonstrate overlapping features, are generally stable over time and are reproducible. What the identification of clusters may have failed to do, is move the needle of precision medicine meaningfully in asthma. This may be related to the lack of a straightforward and clinically meaningful way to apply what we have learned about asthma clusters. Clusters are based on both clinical factors and biomarkers. The use of biomarkers is slowly gaining popularity, but phenotyping based on biomarkers is generally greatly underutilized even in subspecialty care. Biomarkers are more often used to evaluate type 2 (T2) inflammatory signatures and eosinophils (sputum and blood), fractional exhaled nitric oxide (FeNO) and serum total and specific immunoglobulin (Ig) E reliably characterize the underlying inflammatory pathways. Biomarkers perform variably and clinicians must be familiar with their advantages and disadvantages to accurately apply them in clinical care. In addition, it is increasingly clear that clinical features are critical in understanding not only phenotypic characterization but in predicting response to therapy and future risk of poor outcomes. Strategies for asthma management will need to leverage our knowledge of biomarkers and clinical features to create composite scores and risk prediction tools that are clinically applicable. Despite significant progress, many questions remain, and more work is required to accurately identify non-T2 biomarkers. Adoption of phenotyping and more consistent use of biomarkers is needed, and we should continue to encourage this incorporation into practice.
Missed Opportunities: A Cross-Sectional Descriptive Study on Reasons for Nonadherence to the South African Expanded Program on Immunization
Authors: Edwin Roberta , Mackay Cheryl , Mda Siyazi
Published: October 2022

Objective Our objective was to identify factors which underline nonadherence to childhood immunizations provided by the Department of Health and outlined in the Expanded Program on Immunizations in South Africa.

Methods A cross-sectional descriptive study was conducted at Dora Nginza Hospital, a regional hospital in the Eastern Cape Province, which provides free health care in resource-limited settings. It included patients under the age of 5 years and their primary caregivers. A piloted questionnaire was used to collect data, and comparisons were made between children under the age of 5 years who missed one or more immunizations and those with complete immunizations. Data on maternal/caregiver and health system-related characteristics were also collected, and comparisons were made between the two groups.

Results Of the 200 participants enrolled in the study, 47 (23.5%) had incomplete immunizations. Prematurity (odds ratio [OR] = 0.33, p = 0.001), vaccine shortages (OR = 0.22, p < 0.005), and a low maternal/caregiver level of education (OR = 0.32, p = 0.002) were significantly associated with incomplete immunization status.

Conclusion Strategies to improve supply chain management of vaccines and to optimize follow-up care of high-risk children, specifically those born prematurely and those born to women of lower education level, need to be identified and implemented to reduce vaccine-preventable diseases.
The Clinical, Radiological, and Electrophysiological Profile of Children Presenting with Acute Fulminant Cerebral Edema Due to Suspected Encephalitis in an Eastern Indian Tertiary Care Center
Authors: Das Suman , Ray Biman Kanti , Mondal Gobinda , Paul Dilip Kumar , Chatterjee Kaushani , Mishra Lopamudra
Published: October 2022

Objective Our objective was to describe the clinicodemographic, laboratory, and outcome profiles of a rare phenotype of pediatric acute encephalitis syndrome (AES) with acute fulminant cerebral edema (AFCE) and compare them with that of AES without AFCE.

Methods We retrospectively analyzed medical records of a cluster of children hospitalized with encephalitis between June 1, 2021 and December 31, 2021. Their clinical and demographic features, laboratory investigations (hematological, biochemical, serological, microbiological, radiological, and electrophysiological tests), and follow-up data up to 3 months postdischarge were recorded. Patients with AFCE and those without it were divided into groups A and B, respectively, and their characteristics were compared.

Results There were 11 and 15 patients in groups A and B, respectively. There were no significant differences between the two groups in terms of sex, neurological status at admission, hematological and cerebrospinal fluid values, pediatric intensive care unit (PICU) course, and management, etiological identification, and mortality and disabilities at discharge. Patients having reversal or having white cerebellar signs did not significantly differ in their outcomes. However, the patients in group A had significantly lower age, higher incidence of abnormal findings on head computed tomography scans at admission, longer duration of hospitalization, and neurological sequelae at 3 months. The numbers of patients with identified etiologies were zero in group A but five in group B (two Japanese encephalitis, two scrub typhus, and one dengue). Patients of group A had bilateral asymmetric temporal-parieto-occipital T2 hyperintense lesions in magnetic resonance imaging, whereas patients of group B had bifrontal predominant or thalamo-mesencephalic lesions. Multifocal epileptiform discharges were seen in electroencephalogram in both groups, which reverted to normal in 9 and 46% in groups A and B at 3 months, respectively.

Conclusion Younger age is a significant risk factor for the development of AFCE in pediatric AES. AFCE patients have worse outcomes at 3 months, although they do not significantly differ from their non-AFCE counterparts at discharge. When occurring in clusters, AFCE patients exhibit the same radiological and electroencephalographic features.
TransformEHRs: a flexible methodology for building transparent ETL processes for EHR reuse
Authors: Pedrera-Jiménez Miguel , García-Barrio Noelia , Rubio-Mayo Paula , Tato-Gómez Alberto , Cruz-Bermúdez Juan Luis , Bernal-Sobrino José Luis , Muñoz-Carrero Adolfo , Serrano-Balazote Pablo
Published: October 2022

Background During the COVID-19 pandemic, several methodologies were designed for obtaining electronic health record (EHR)-derived datasets for research. These processes are often based on black boxes, on which clinical researchers are unaware of how the data were recorded, extracted, and transformed. In order to solve this, it is essential that extract, transform, and load (ETL) processes are based on transparent, homogeneous, and formal methodologies, making them understandable, reproducible, and auditable.

Objectives This study aims to design and implement a methodology, according with FAIR Principles, for building ETL processes (focused on data extraction, selection, and transformation) for EHR reuse in a transparent and flexible manner, applicable to any clinical condition and health care organization.

Methods The proposed methodology comprises four stages: (1) analysis of secondary use models and identification of data operations, based on internationally used clinical repositories, case report forms, and aggregated datasets; (2) modeling and formalization of data operations, through the paradigm of the Detailed Clinical Models; (3) agnostic development of data operations, selecting SQL and R as programming languages; and (4) automation of the ETL instantiation, building a formal configuration file with XML.

Results First, four international projects were analyzed to identify 17 operations, necessary to obtain datasets according to the specifications of these projects from the EHR. With this, each of the data operations was formalized, using the ISO 13606 reference model, specifying the valid data types as arguments, inputs and outputs, and their cardinality. Then, an agnostic catalog of data was developed through data-oriented programming languages previously selected. Finally, an automated ETL instantiation process was built from an ETL configuration file formally defined.

Conclusions This study has provided a transparent and flexible solution to the difficulty of making the processes for obtaining EHR-derived data for secondary use understandable, auditable, and reproducible. Moreover, the abstraction carried out in this study means that any previous EHR reuse methodology can incorporate these results into them.
The sharing economy in the hospitality sector: The role of social interaction, social presence, and reciprocity in eliciting satisfaction and continuance behavior
Authors: Lho Linda Heejung , Quan Wei , Yu Jongsik , Han Heesup
Published: October 2022

The sharing economy is still transforming the hospitality industry at an exponential speed. The idea of acquiring goods and services through a collaborative approach is becoming a significant part of the world’s overall economy. Many use platforms and social media channels to make purchase decisions while communicating with others. This study, therefore, investigates the socialization factors and values of the sharing economy as driving forces of the rapid growth of the hospitality businesses related to sharing economy. The study also assesses their influence on satisfaction and continuance behavior and explores the role of reciprocity and perceived risk by applying the value-based adoption theory. Using mixed methods, the present research identifies the crucial attributes and validates the proposed theoretical framework. Our findings provide valuable insights for hospitality businesses participating in the sharing economy.