bluuebunny/crossref_metadata_2025 huggingface dataset:
שלוש־עשרה אלף שנים במדבר
Authors: רביד מעין
Published: December 2024

בדצמבר 2013 נפתח מתקן הכליאה חולות בנגב. במהלך חמש שנות פעילותו נכלאו בו כ־13 אלף גברים מסודאן ומאריתריאה לתקופות של שנה או יותר. מסה זו מבקשת לתת עדות לאירוע מכונן זה, שבמרוצת השנים והאירועים המתגלעים בישראל יישכח כלא היה, אבל עבור מי שהיו בחולות הוא נחקק בגוף ובתודעה לעד. העדות על חולות שזורה בסיפורו האישי של אדהם, גבר סודאני שחור שחיפש מקלט בישראל ונכלא במתקן, ובסיפורה האישי של הכותבת – אישה ישראלית לבנה שפנתה מפעילות חברתית לכתיבה אקדמית מתוך המפגש עם אלימות מדינתית מפלה. התבוננות במדיניות הכליאה בחולות דרך הפריזמה האפרופסימית לאורך המסה מאירה על היחסים ההיררכיים הדיאלקטיים המבדילים בין השחור לאנושי, הנבנים באמצעות אלימות. דרך חשיבה מול כתיבתם של ויליאם דו בויז וסעידיה הרטמן אנו מתוודעים לעולמות נפרדים שמתקיימים במקביל לאורך ההיסטוריה, המתעצבים דרך נידוי ודחיקת האדם השחור אל מחוץ לקיום האנושי. הפרקטיקה של כליאה במדבר הייתה הדרך הפיזית והמוחשית של המדינה להרחיק את האחר, השחור, שאינו זכאי להתקיים בגבולותיה כאדם שווה ערך; אך תהליכים הדרגתיים של ביטול האנושיות קדמו לכליאה והכשירו אותה. בישראל צברנו ניסיון בכינון תהליכי הדרה, הפחדה, הפללה וזילות לאור נרטיב סלקטיבי של שייכות, שממקם את "האחר" מחוץ לעולם ותוך כדי כך מוחק אותו. השילוב בין נרטיב אישי לשיח תיאורטי בנושא מאפשר רפלקציה על המיקומים הספציפיים והיחסים החברתיים הסובבים את הכתיבה על שחורוּת ולובן מקומי. מדובר במיקומים אישיים ופוליטיים וביחסים המאופיינים באי־שוויון עמוק במסגרת יחסי הכוחות המוגזעים שבהם צמחו – בין לבנים לשחורים, בין יהודים אשכנזים לאחרים, בין החוקרת למבקש המקלט, בין חברוּת למציאות חברתית מבדלת סביבה. דרך רפלקציה אישית ותיאורטית, ובאופן מודע שמכיר ביחסי הכוחות השוררים בהקשר המקומי ובהשפעתם, משרטטת המסה קווים לעשייה ולכתיבה הנוגעות להדרה ולאוכלוסיות מודרות. עשייה וכתיבה אחראית הן כאלה שאינן נשענות על קטגוריות בינריות מחוץ, אלא מתעצבות מול הסביבה הספציפית ולובשות תצורה מקומית על גווניה הייחודיים.
הונאה עצמית, פנון ועליית השמאל הימני: ריאיון
Authors: גורדון לואיס ר' , זאוודו גבינש אדנה
Published: December 2024

הריאיון שערך אדנה זאוודו גבינש עם לואיס גורדון חוזר לספרו הראשון של גורדון, Bad Faith and Antiblack Racism, אשר ראה אור לראשונה בשנת 1995 ועתיד לצאת במהדורת ה־30. דרך הספר דנים גורדון וזאוודו גבינש בתובנה הפנומנולוגית של גילום התודעה בגוף (embodiment), בחקירה של גזענות אנטי־שחורה כצורה של הונאה עצמית (bad faith) וכן בניגודה, ״תום לב ביקורתי״. הריאיון עוסק גם בכתיבתו של גורדון על פנון ובמחשבותיו בנוגע לפוליטיקה של ישראל/פלסטין אחרי שבעה באוקטובר. בניגוד לנטייה לקרוא את מקוללים עלי אדמות של פנון דרך אחד מפרקיו שרבים חושבים כי הוא מעניק לגיטימציה לאלימות במאבק בקולוניאליזם, גורדון מציע להביע את היחס של פנון לאלימות במונחים של טרגדיה. באופן הזה, לפי גורדון, השימוש באלימות אצל פנון הופך ל״אנטי־אלימות״, על דרך ההנגדה לאלימות הקולוניאלית ולצורות של דה־הומניזציה. מתוך הישענות על נקודה זו מצביע גורדון בין היתר על הדיאלקטיקה השמרנית שבאה לידי ביטוי בקרב אנשי שמאל בישראל.
Computer-Mediated Turn Allocation Technique: A Veritable Tool Employ by Yoruba/English Bilinguals on the Internet
Authors: Akinyede Rotimi Gbenga , Gbenga Alonge Sunday
Published: December 2024

This study examines how Yoruba-English bilinguals organize their thoughts to be mutually intelligible in their conversations on the Internet. Specifically, the research investigates how Yoruba-English bilinguals apply “Turn Allocation Technique” as a veritable tool that makes conversations on the Internet meaningful which is the essence of communication, and also investigates the occurrences of bilingualism by-products such as, code-mixing and hybridization on Facebook, WhatsApp, etc. The data are obtained from a survey on social media platforms with a view to achieving an adequate understanding of some aspects of “Turn Allocation Technique” in the conversations of Yoruba-English bilinguals. Different interactions on the Internet were chosen. Therefore, we examined how the subjects code-switch and code-mix while taking turn to communicate on the Internet. A context-driven sociolinguistic model is employed as our guide in analyzing the data. This is Harold Garfinkel’s Ethnomethodology of Language. In employing ethnomethodology of language, we tried to see the conventions of society, and the rules which people use to place themselves and others in social contexts. The study reveals that interlocutors take turn to chat unlike an SMS, they exhibited great dexterity by using the two languages together in a sentence without its meaning being distorted, and the interactants on employ ‘Turn Allocation Technique’ to organize their conversations so that there would be mutual intelligibility. It is established in this study that the contact between the speakers of English and Yoruba has led to bilingualism which has its consequences. Some of the consequences of bilingualism are code-switching/code-mixing, interference, hybridization, etc.
Existentialism: A Self Maker Philosophy and its Implications on Education
Authors: ADELEYE Joseph Olusola
Published: December 2024

This paper rationalizes man as a self-maker being because man is a free being who is capable of living his life the way he wants. The concept of determinism is an absurdity to the existentialists since man cannot be separated from exercising his freedom and as well be ready to face the consequence of the action taken. He is a subject and not an object that can be manipulated like a robot. His freedom attests to him as a moral agent who is rational and can choose for himself what to do, how to do it and when to act instead of compromising his nature. Based on this, the paper examines existentialism as a school of thought and a choice making philosophy, rationalizes freedom as well as responsibility and their implications on education. This is qualitative research in education which makes use of language and logical reasoning throughout.
Staff Use and Satisfaction with Open Source Software in the Management of Selected Federal Universities’ Libraries in South Nigeria
Authors: Okoh Helen Ewere , Iwhiwhu Basil Enemute
Published: December 2024

Aim of the Study: Libraries are the key source of knowledge and information in the educational setups especially in universities. The aim of the current study to explore the use and satisfaction of open source software by university library workers in Nigeria.
Methodology: The study was conducted using a survey-type descriptive research design. The study's sample size was (N=203), which represented every member of the library staff at the chosen university libraries as a whole. The “Library Staff Use and Satisfaction with Open Source Software Questionnaire (LSUSOSSQ)” was used as the instrument for data collection and the census sample technique was used for the study. By employing the test-retest procedure and the Pearson Product Moment Correlation Coefficient (r), which produced a reliability coefficient of 0.84, the instrument's reliability was increased. From the whole population of 203, in return 195 copies of the questionnaire were received and noted 96.1% return rate. To address the study issues, data were examined using descriptive statistics like mean and standard deviation, and the t-test to evaluate the hypotheses at a significance level of 0.05.
Findings & Conclusion: The study found that university libraries in South-South Nigeria used the administration, cataloguing, and circulation modules of OSS extensively and had high levels of satisfaction with their use. The study suggested using OSS in university libraries in Nigeria to facilitate teaching and research, which will also increase the visibility of Nigerian academics in the committee of scholars across the world.
Information Communication Technology in Teaching/ Learning Process: The New Instructional Media in Developing World
Authors: R.G. Akinyede  , S.G Alonge
Published: December 2024

Access to prompt, adequate and reliable information is very vital in teaching/learning process. This is exactly what ICT provides. ICT is an alphabetism that stands for Information Communication Technology. In recent years, all human endeavours depend largely on ICT for optimum performance and good result. This paper examines the meaning of ICT and how it affects the dissemination of information. Also, the paper critically looks at the stumbling blocks on the path of teachers to effectively use the ICT to the benefit of their learners. Recommendations were also made in order to proffer solutions to the stumbling blocks on the path of teachers.
Motivating Employees for Performance in the 21st Century: A Content Discuss
Authors: EGBERI Anthony Ejue
Published: December 2024

Motivating an employee towards improving performance is imperative and constitutes one of the cardinal aim and goal for any organization.  This should be the key objective in today’s organization. However, recent recurrent challenges seem to be the issue of poor employees’ performance. This study focuses on the potential performance of today employees in an organization as he/she is affected by the motivational level offered by the organization. The study is anchored on Maslow's Hierarchy of Needs, McClelland's Three Needs Theory, and Herzberg's Motivation Theory. The study is a content analysis. Data for the study were generated from secondary source. Such data were analysis descriptively. The study raises a host of questions and answer them through conceptual clarification and conclusion made.
Analisis Kompetensi Pedagogik Guru Pendidikan Anak Usia Dini Berdasarkan Latar Belakang Pendidikan
Authors: Yusuf Hijrawati , Sabani Fatmaridah , Hasis Pertiwi Kamariah , Makmur  , Eka Poppi Hutami
Published: December 2024

This research discusses the analysis of PAUD teachers' pedagogical competencies based on educational background. This research aims to determine the educational background of teachers. The type of research used is qualitative research. Data collection uses observation, interview and documentation techniques. The methods used were observation, interviews and documentation. The research subjects were teachers at Mutiara Bunda Kindergarten, Bassiang Village. The analysis used is Data Reduction, Data Display and Conclusion Drawing. The results of this research show that: 1). In class A1 teachers who have a bachelor's educational background in Islamic religious education and have additional competencies, namely Training to Increase Insight into Early Childhood Education and Technical Guidance for GEBRAK PAUD (Early Childhood Education Transition Movement), in class A2 teachers who have an educational background Bachelor's degree in English and has never attended any training. Class B teachers are high school graduates and additional competency is training to increase insight into early childhood education. 2). The obstacles experienced by teachers when teaching based on educational background at Mutiara Bunda Kindergarten in Bassiang Village include obstacles faced by teachers in mastering the material, obstacles faced by teachers in using teaching aids, obstacles faced by teachers in using appropriate teaching methods, obstacles faced by teachers in managing the class.
Bezpieczeństwo konsumentów w świecie gospodarki współpracy z perspektywy prawa Unii Europejskiej – analiza wybranych problemów
Authors: Kucharska Anita
Published: December 2024

Artykuł podejmuje tematykę sytuacji konsumenta w gospodarce współpracy z perspektywy prawa Unii Europejskiej. Zjawisko collaborative economy, ze względu na swój dopiero kształtujący się charakter, stanowi źródło licznych, jak dotychczas w niewielkim stopniu omówionych, problemów prawnych. Jednym z fundamentalnych zagadnień, które wymagają natychmiastowego przeanalizowania, jest wybór właściwej metody, która będzie chroniła nabywców usług. Bezpieczeństwo użytkowników platform powinno zostać ukształtowane przy odpowiednim wykorzystaniu obowiązujących przepisów z zakresu prawa konsumenckiego oraz ze szczególnym uwzględnieniem natury środowiska gospodarki współpracy. Autorka przedstawia tezę o konieczności wprowadzenia dwóch reżimów prawnych: surowszego (dedykowanego podmiotom dostarczającym usługi w sposób profesjonalny) oraz lżejszego (skierowanego do podmiotów nieprofesjonalnych).
Obowiązek badania przez sąd krajowy z urzędu abuzywności klauzuli umownej, a gwarancja skutecznej ochrony interesów konsumenta
Authors: Sieńko-Kowalska Beata
Published: December 2024

W celu zapewnienia odpowiedniego poziomu zamierzonej przez unijnego ustawodawcę ochrony konsumentów sąd krajowy jest zobowiązany do przywrócenia – w każdym wypadku i niezależnie od przepisów prawa krajowego – rzeczywistej równowagi kontraktowej pomiędzy konsumentem a przedsiębiorcą-profesjonalistą. Gwarancja skutecznej ochrony konsumentów oznacza zbadanie czy sporne postanowienie umowne zostało indywidualnie uzgodnione przez przedsiębiorcę i konsumenta, a także wykorzystanie wszystkich możliwych środków, aby uwzględnić również z urzędu niedozwolony charakter postanowienia umownego, nawet jeśli sąd ocenia, że konsument tego aspektu nie podniósł na żadnym etapie procesu. Funkcjonujące dwa mechanizmy kontroli, tj. kontrola abstrakcyjna oraz incydentalna mają wspólny i zarazem nadrzędny cel, którym jest zagwarantowanie konsumentom ochrony, co najmniej na poziomie wyznaczonym postanowieniami dyrektywy 93/13/EWG, czy to przez Prezesa UOKiK jako organu administracji publicznej, czy to przez polskie sądy powszechne.
What is the main cause of childhood non-cystic fibrosis bronchiectasis in the developing world – should pulmonary tuberculosis be the number one accused?
Authors: Goussard P , Eber E
Published: December 2024

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Les consultations d’éthique clinique en France : origines, perspectives et prémisses d’un collectif
Authors: Galmiche Perrine
Published: December 2024

En France, la pratique de l’éthique clinique, et plus spécifiquement de la consultation d’éthique clinique (CEC), est marquée à la fois par un héritage des pratiques outre-Atlantique et par une volonté de s’adapter aux nécessités du contexte national qui laisse de plus en plus de place à la voix des patients. Alors que la pratique reste longtemps marginale dans le pays, de nombreuses structures se sont développées à la suite de la crise sanitaire de la Covid-19. L’objectif de cet article est de poser un premier regard national sur la pratique de la CEC en France, de ses origines à ses perspectives. Un questionnaire à visée exploratoire a été établi par 5 équipes proposant une CEC liées par un partenariat historique. Il comprenait 4 parties : présentation de la structure, forme que prend la CEC, adhésion ou non à des propositions de fondamentaux, volonté éventuelle de former un collectif national des CEC. Les résultats portent sur 38 structures, dont 26 indiquent pratiquer la CEC. Si ces 26 structures font part de pratiques hétérogènes, elles se rejoignent sur l’objectif de proposer une aide à la décision médicale au cas par cas, une majorité adhère aux fondamentaux identifiés et souhaite participer à un collectif des CEC. Cette première exploration invite à mettre en perspective la pratique de la CEC en France dans le contexte international, et ouvre des perspectives de travail collectif sur les fondamentaux pratiques et méthodologiques, autant en s’appuyant sur les similitudes qu’en cultivant les différences.
Voluntary Assisted Dying: The Impasse and a Way Forward
Authors: Dankwort Juergen
Published: December 2024

The project to provide voluntary assisted dying (VAD) has grown significantly and at an accelerating rate over the past two decades in over 30 countries on four continents. Yet, concomitant with this rise is an increasing opposition to it based on legal, medical, and ethical grounds advanced by a wide range of detractors, giving pause to projects already underway, and bringing its enlargement to a halt. Simultaneously, persons seeking relief from suffering continue to be denied VAD access or are forced to wait for it by decreed compulsory living. Those assisting beyond the legislated parameters of a VAD regime are facing criminal prosecution. The contraposition to VAD has raised the risk of desperate persons seeking relief by committing violent suicide, endangering family, friends, and first responders. In light of this concerning development, I identify how the prevailing legislated approach at the source of these issues is both paradigmatic and problematic. Amendments to existing prohibitions for assisted dying or homicide become the foundation of an assisted dying regime that codifies its essential features, including client typology, life quality for service access or its denial, who is authorized to provide VAD, and when and how it can be administered. While this approach continues to be replicated extensively and has provided some relief to unbearable living, I show how an alternative, time-tested, evidence-based approach for VAD offers an optional pathway that could avoid many of the most challenging aspects of the prevalent model.
Global Living Ethics: Unveiling Practical and Theoretical Synergies Through Reflexive Balancing
Authors: Boudreau LeBlanc Antoine
Published: December 2024

Exploring the complex landscape of bioethics, this article combines the theoretical insights of the Potterian Global Bio-Ethics approach with bioethics research methods, aiming for actionable ethical compromises in governance. The Potterian approach transcends traditional disciplinary boundaries, adopting John Dewey’s pragmatist view, and bringing into convergence philosophical and empirical methods. I advocate for a synergy between micro-scale local-empirical and macro-scale global-rational approaches. Presenting a hands-on case for bioethicists, I emphasize a ‘Global’ bioethics perspective, grounded at the individual scale. Drawing on concepts like ‘boundary-object’ and ‘hybrid community’ from Susan Star and Michel Callon, I propose a reflexive methodology with tools for mapping, framing, and shaping ethical inquiries, to avoid fallacies and embed values in problem-solving. This approach strives to connect meta-ethical reflections with daily bioethical challenges, promoting a coherent, reflexive, and pragmatic methodology.
Comunicar la buena educación: las ‘eduinfluencers’ (y II)
Authors: Costa Gálvez Lola
Published: December 2024

En la primera parte de este artículo, siete eduinfluencers nos explicaron qué las inspira a la hora de compartir contenido educativo en las redes sociales, qué retos les plantea esta práctica, cómo eligen las temáticas abordadas y cómo garantizan la rigurosidad de dichos contenidos. En esta segunda y última entrega, esas docentes dan respuesta a las tres preguntas que completan la entrevista realizada por la autora.
The Performance of Different Freight Wagon Bogie Types on a Small Radius Curve – Comparison of Field Measurements and Simulations
Authors: Loponen Tiia-Riikka , Shaik Rizwanullah , Varis Riku , Luomala Heikki , Kolisoja Pauli
Published: December 2024

The running performance of different freight wagons affects the damage they cause to the track, which in turn influences the maintenance costs of the track. The track access charges may be imposed based on the track friendliness of a wagon if the features of the wagons are known. In Finland, besides the structure of the bogies, the width of the bogies also varies since some of the bogies are designed for a track gauge of 1524 mm and some for a track gauge of 1520 mm. In this paper, the performance of different freight wagon bogies on a small radius curve is investigated by means of field measurements and simulations. Wheel-rail contact forces and angle of attack values of six different wagon types are measured. In addition, simulations are created to gain further knowledge on wheel-rail contact forces, angle of attack values, and wear values. Based on this research, it would be beneficial to use a wider track gauge in small radius curves to make the curve negotiation easier for some bogie types. It was also noticed that a small radius curve with only a short transition zone could be very risky regarding derailment potential, especially for empty wagons.
A systematic review and meta-analysis of eyespot anti-predator mechanisms
Authors: Mizuno Ayumi , Lagisz Malgorzata , Pollo Pietro , Yang Yefeng , Soma Masayo , Nakagawa Shinichi
Published: December 2024

Eyespot patterns have evolved in many prey species. These patterns were traditionally explained by the eye mimicry hypothesis, which proposes that eyespots resembling vertebrate eyes function as predator avoidance. However, it is possible that eyespots do not mimic eyes: according to the conspicuousness hypothesis, eyespots are just one form of vivid signals where only conspicuousness matters. They might work simply through neophobia or unfamiliarity, without necessarily implying aposematism or the unprofitability to potential predators. To test these hypotheses and explore factors influencing predators’ responses, we conducted a meta-analysis with 33 empirical papers that focused on bird responses to both real lepidopterans and artificial targets with conspicuous patterns (i.e. eyespots and non-eyespots). Supporting the latter hypothesis, the results showed no clear difference in predator avoidance efficacy between eyespots and non-eyespots. When comparing geometric pattern characteristics, bigger pattern sizes and smaller numbers of patterns were more effective in preventing avian predation. This finding indicates that single concentric patterns have stronger deterring effects than paired ones. Taken together, our study supports the conspicuousness hypothesis more than the eye mimicry hypothesis. Due to the number and species coverage of published studies so far, the generalisability of our conclusion may be limited. The findings highlight that pattern conspicuousness is key to eliciting avian avoidance responses, shedding a different light on this classic example of signal evolution.
Marcks and Marcks-like 1 proteins promote spinal cord development and regeneration in Xenopus
Authors: El Amri Mohamed , Pandit Abhay , Schlosser Gerhard
Published: December 2024

Marcks and Marcksl1 are abundant proteins that shuttle between the cytoplasm and membrane to modulate multiple cellular processes, including cytoskeletal dynamics, proliferation, and secretion. Here, we performed loss- and gain-of-function experiments in Xenopus laevis to reveal the novel roles of these proteins in spinal cord development and regeneration. We show that Marcks and Marcksl1 have partly redundant functions and are required for normal neurite formation and proliferation of neuro-glial progenitors during embryonic spinal cord development and for its regeneration during tadpole stages. Rescue experiments in Marcks and Marcksl1 loss-of-function animals further suggested that some of the functions of Marcks and Marcksl1 in the spinal cord are mediated by phospholipid signaling. Taken together, these findings identify Marcks and Marcksl1 as critical new players in spinal cord development and regeneration and suggest new pathways to be targeted for therapeutic stimulation of spinal cord regeneration in human patients.
A polyphasic approach in the identification and biochemical characterization of Dunaliella tertiolecta with biodiesel potential from a saltern in Mauritius
Authors: Ramdhony Kamlesh , Puchooa Daneshwar , Faraj Turki Kh. , Alrefaei Abdulwahed Fahad , Li JunFu , Jeewon Rajesh
Published: December 2024

Bioprospecting robust and oleaginous strain is crucial for the commercialization of microalgae-based biodiesel. In this study, a microalgal strain SCH18 was isolated from a solar saltern located in Mauritius. This isolate was identified as Dunaliella tertiolecta based on a polyphasic approach that combined molecular, physiological, and morphological analyses. Furthermore, the effect of different salinities on the biochemical composition and fatty acid profile of this microalga was investigated to explore its potential in producing biodiesel. Results from the growth studies showed that salinity of 1.0 M NaCl was optimal for achieving a high growth rate. Under this salt concentration, the growth rate and the doubling time were calculated as 0.39 ± 0.003 day−1 and 1.79 ± 0.01 days, respectively. In terms of biochemical composition, a substantial amount of carbohydrate (42.02 ± 5.20%), moderate amount of protein (30.35 ± 0.18%) and a low lipid content (17.81 ± 2.4%) were obtained under optimal NaCl concentration. The fatty acid analysis indicated the presence of palmitic acid, stearic acid, palmitoleic acid, oleic acid, linoleic acid, gamma, and alpha-linolenic acids, which are suitable for biodiesel synthesis. The predicted biodiesel properties were in accordance with the standard of ASTM 6751, indicating that the microalgal isolate D. tertiolecta SCH18 is a potential candidate for use in biodiesel production.
Análise sobre a satisfação do cliente por meio do atendimento online em uma concessionária de veículos de Ituiutaba-MG
Authors: Santos Ana Letícia Candido , Silva Bruna Caroline Brito , Silva Janaina de Oliveira , Martins Nayany Santos , Martins Lucas Carvalho
Published: December 2024

O atendimento online é de extrema importância para as organizações, pois contribui positivamente para a empresa, apresentando mais competitividade diante de seus concorrentes. O atendimento online acontece dentro das ferramentas de mídias digitais, nas quais o atendente não possui contato direto com seu cliente. O presente estudo aborda a importância da qualidade no atendimento online como um diferencial competitivo para as organizações. O objetivo geral desta pesquisa é realizar um estudo de caso através de entrevista estruturada, sobre o nível de satisfação dos clientes de uma concessionária de veículos na cidade de Ituiutaba-MG, referente aos serviços online oferecidos pelo setor de vendas da empresa. A metodologia utilizada foi o modelo quantitativo com a utilização da estatística descritiva e inferencial, por meio do teste qui-quadrado de independência, observando que mesmo os entrevistados ficando 100% satisfeitos com o atendimento online para orçamentos e serviços gerais, 85% dos entrevistados não optariam pelo atendimento 100% online para realização da compra de um veículo. Pode-se afirmar também com 95% de confiança, através dos testes de hipóteses feitos, que não existe associação entre idade e a preferência pela compra de um veículo 100% online, não existe associação entre o gênero e a preferência pela compra 100% online, não existe associação entre o nível de escolaridade e a preferência pela compra 100% online e não existe associação entre estado civil e a preferência pela compra 100% online.
Gestão e inovação: implementação de uma nova formação adicional para gestores em saúde no campo da medicina social
Authors: Morcerf Cely Carolyne Pontes , Moreira Fernando de Moura , Amorim Lucas Silva de , Marques João Mazzoncini de Azevedo
Published: December 2024

Na evolução histórica de criação de um programa de residência, inserido no campo da medicina social, identificou-se a existência de uma diversidade de problemas subjetivos, que comprometiam a qualidade e o desempenho de indicadores frente à procura de inscrições no processo seletivo do programa, assim como o nível de satisfação do residente que reduzia com o tempo. Esse cenário evoluiu associado à existência de ruídos de comunicação internos que prejudicavam a atratividade de um programa com tradição de excelência no passado, na formação de lideranças clínicas voltadas ao treinamento no Sistema Único de Saúde (SUS). Realizou-se um diagnóstico para visualização de um problema em potencial voltado à carência de especializações em área prioritária de saúde pública: a formação específica de gestão em Medicina de Família e Comunidade (MFC). Esse estudo busca relatar a experiência de idealização e implementação de um programa pioneiro de formação de médicos gestores, com pré-requisito em MFC e com um cronograma de formação de imersão na gestão em redes, não apenas restrito à gestão hospitalar ou da atenção primária. Tal formulação utilizou a metodologia do Design Thinking e possibilitou uma visão ampliada dos principais problemas do seguimento da gestão, existentes em cada nível de atenção, assim como os fatores potencializadores da gravidade do problema inerentes à fragilidade de integração e diálogos entre os serviços de saúde, prejudicando consequentemente o cuidado integrado e centrado nas pessoas e reduzindo a resolutividade de serviços e sistemas de saúde.
PROCESSO DE IMPLEMENTAÇÃO DA BNCC NO ÂMBITO DA GESTÃO E DA DOCÊNCIA
Authors: Dos Anjos Ricardo Eleutério , Coelho Lurdinei de Souza Lines , Crespi Maria Clara Favarão
Published: December 2024

O artigo analisa a participação de gestores e professores na implementação da BNCC em uma Diretoria de Ensino localizada no interior do estado de São Paulo. Para exposição dos resultados foram selecionados quatro eixos de análise: a) o processo de formação referente à implementação da BNCC; b) participação no processo de implementação da BNCC; c) percepções de gestores e professores sobre o processo de implementação da BNCC quanto aos impactos na qualidade da educação e; d) o processo de implementação da BNCC e seus impactos no trabalho educativo. Observou-se uma ínfima participação na elaboração do documento e um precário conhecimento do processo de implementação por parte dos gestores e professores.
Assessment of Some Heavy Metals Concentration and pH in Some Seafoods Found in Borokiri, Trans-Amadi, Eagle Island and Iwofe Swamps, Rivers State Nigeria
Authors: U.A. Obisike, , G.N. Offor,
Published: December 2024

Aim: To assess the levels of heavy metals (cadmium, lead, chromium, copper), and pH in periwinkles, whelks, oysters, sediment, and water found in some swamps in Rivers State.
Study Design: Analytical Cross-sectional study.
Place and Duration of Study: Borokiri, Trans-Amadi, Eagle Island and Iwofe swamps, Rivers State Nigeria, between June and December 2022.
Methodology: Samples were collected from four different swamps in Rivers State: Iwofe, Eagle-Island, Trans-Amadi, and Borokiri swamps. Eagle-Island and Iwofe swamps are in Obio/Apkor LGA, while Trans-Amadi and Borokiri swamps are in Port Harcourt LGA. The solid samples were ground to powdered form to attain homogenous particles. Each sample was weighed, recorded and the concentrations of metals in the samples were determined. Five hundred (500) milligrams each of the ground samples were weighed and put into a crucible, 20 ml aqua regia (comprising 15 ml HCI and 5 ml HNO3) was added to digest the sample. Heavy metals in the digested samples were analyzed using GBC XplorAA Atomic absorption spectrophotometer (AAS). Where the concentrations were calculated using Beer-Lambert’s law. The statistical analysis was done using GraphPad Prism version 8.0.2 of Apple Macintosh HD Big Sur (version 11.0). Descriptive statistical tools such as mean & standard deviation (SD) were used. ANOVA was used to compare means of more than two groups for inferential evaluation, with Tukey’s multiple comparison test to check for mean difference between multiple groups. The probability (p) value less than 0.05 (P<0.05) was used and considered statistically significant.
Results: The results showed that the mean concentrations of cadmium, copper, and lead (0.001 ± 0.0001mg/l, 0.16 ± 0.07mg/l, and 0.01±0.003 mg/l respectively) were below the standard limit set by the World Health Organization (WHO), while chromium exceeded this limit, and the pH was also within acceptable range. From the results observed in the sediments and the tissue samples, the level of cadmium was below the standard limit set by WHO. However, chromium, copper, and lead had concentrations that were above the WHO recommended limit
Conclusion: Campaigns need to be launched to educate the public about the risks to health posed by improper disposing of household and municipal waste, industrial effluents, and pipelines, as well as the toxicity of heavy metals.
Surgical Removal of a Large Osteoma in the Frontal Bone and Treatment of Facial Fractures: An Integrated Approach
Authors: Metchko Matheus Felipe Lemes , Morakami Ana Beatriz Kazmierski , Berardi Ellen Constantino , Checom Heloisa Conti , Bachesk Andressa Bolognesi
Published: December 2024

Osteoma is a benign osteogenic tumor of unknown etiology, with no predilection for nationality, race, gender, or age. It typically presents in small diameters, with large extensions being rare. The prognosis in these cases is closely tied to early diagnosis, often made during clinical inspections, identifying asymptomatic lesions or those associated with pain and asymmetry. For this reason, the dentist must be vigilant in identifying any abnormalities in patients, even those outside their specific field of practice. This paper aims to report a clinical case of a 56-year-old male patient with fair skin who presented to the hospital following facial trauma. After clinical and imaging examinations, he was diagnosed with multiple facial fractures as well as a large osteoma in the atypical region of the frontal bone, which caused visual interference on the right side. The integrated treatment involved a combination of bicoronal and circumvestibular approaches for the surgical removal of the osteoma, along with the stabilization and fixation of the frontozygomatic suture, Le Fort I fracture, and hemi-Le Fort II fracture using 2 mm titanium plates. After 5 years of follow-up, the patient remained free of complaints or sequelae, in good general health, and with no signs of recurrence. Although osteomas are often asymptomatic, in this case, the tumor caused significant facial asymmetry and visual disturbances due to the compression of adjacent structures, proportional to its size.
Seasonal Diversity of Insect Pollinators on Cucurbit Vegetables
Authors: Chaudhary D. V. , Deb Sushma , Thakar P. K.
Published: December 2024

Total 24 and 23 insect pollinators were observed on cucurbit vegetables from initiation of flowering to cessation of flowering during different hours of the day in kharif 2022 and kharif 2023, respectively. The insect pollinators represented from four orders viz., Hymenoptera, Lepidoptera, Orthoptera and Diptera with the families viz., Apidae, Scoliidae, Megachilidae, Vespidae, Muscidae, Syrphidae, Tettigoniidae, Pieridae, Nymphidae, Crambidae, Papilionidae, Hesperiidae, Lycaenidae and Sphingidae. Apis dorsata was the prominent insect pollinator throughout the both seasons on cucurbit vegetables.
A Mediated Analysis of Capital Structure: The Effects of Size, Profitability, and Asset Growth on Firm Value in Indonesia’s Food and Beverage Sector
Authors: Dhiana Karin Sukma , Purwidianti Wida , Innayah Maulida Nurul , Utami Restu Frida
Published: December 2024

Aims: This study examines the influence of company size, profitability (ROE), and asset growth on firm value (Tobin's Q) through company capital structure (DER).
Study design: This research design is quantitative research with a balanced panel data regression approach and Sobel test to test the relationship between company size, profitability and asset growth variables on firm value and the mediating role of capital structure in the relationship.
Place and Duration of Study: Food and beverage companies listed on the Indonesia Stock Exchange for 2020-2023.
Methodology: The method used is linear regression and uses the Sobel test to analyse the mediating role of capital structure in the relationship between independent variables and dependent variables. In addition, this study uses a quantitative approach to analyse data using multiple linear regression, which tests the effect of independent variables (Company Size, Profitability, and Asset Growth) on the dependent variable (Company Value) and the mediating variable (Capital Structure). The population used is food and beverage companies listed on the Indonesia Stock Exchange for the period 2020-2023, and took a sample of 34 companies that met the sample criteria.
Results: Regression analysis demonstrates that company size and profitability have a significant positive effect on firm value, while company size has a significant negative effect on firm value and in contrast to profitability which has a significant positive effect on firm value.
Conclusion: As companies grow in size and profitability, they tend to rely more heavily on debt financing to support their expansion. In developing countries, firms often prioritize debt financing to drive growth and enhance firm value. By increasing profitability, firms can maximize their value.
ZNF281/Zfp281 is a target of miR‐1 and counteracts muscle differentiation
Authors: Nicolai Sara , Pieraccioli Marco , Smirnov Artem , Pitolli Consuelo , Anemona Lucia , Mauriello Alessandro , Candi Eleonora , Annicchiarico‐Petruzzelli Margherita , Shi Yufang , Wang Ying , Melino Gerry , Raschellà Giuseppe
Published: November 2019

Defects in achieving a fully differentiated state and aberrant expression of genes and microRNAs (miRs) involved in differentiation are common to virtually all tumor types. Here, we demonstrate that the zinc finger transcription factor ZNF281/Zfp281 is down‐regulated during epithelial, muscle, and granulocytic differentiation in vitro. The expression of this gene is absent in terminally differentiated human tissues, in contrast to the elevated expression in proliferating/differentiating ones. Analysis of the 3’UTR of ZNF281/Zfp281 revealed the presence of numerous previously undescribed miR binding sites that were proved to be functional for miR‐mediated post‐transcriptional regulation. Many of these miRs are involved in differentiation pathways of distinct cell lineages. Of interest, ZNF281/Zfp281 is able to inhibit muscle differentiation promoted by miR‐1, of which ZNF281/Zfp281 is a direct target. These data suggest that down‐regulation of ZNF281/Zfp281 during differentiation in various cell types may occur through specific miRs whose expression is tissue‐restricted. In addition, we found that in rhabdomyosarcoma and leiomyosarcoma tumors, the expression of ZNF281/Zfp281 is significantly higher compared with normal counterparts. We extended our analysis to other human soft tissue sarcomas, in which the expression of ZNF281 is associated with a worse prognosis. In summary, we highlight here a new role of ZNF281/Zfp281 in counteracting muscle differentiation; its down‐regulation is at least in part mediated by miR‐1. The elevated expression of ZNF281/Zfp281 in soft tissue sarcomas warrants further analysis for its possible exploitation as a prognostic marker in this class of tumors.
GSTZ1‐1 downregulates Wnt/β‐catenin signalling in hepatocellular carcinoma cells
Authors: Lei Chong , Wang Qiujie , Tang Ni , Wang Kai
Published: November 2019

Glutathione S‐transferase Zeta 1‐1 (GSTZ1‐1), an enzyme involved in the catabolism of phenylalanine and the detoxification of xenobiotics, plays a tumour suppressor role in hepatocellular carcinoma (HCC), but the underlying mechanism remains largely unknown. Here, we further explored the function of GSTZ1‐1 in HCC through transcriptome analysis by RNA sequencing. The analysis revealed that 223 genes were upregulated and 290 genes were downregulated in GSTZ1‐1‐overexpressing Huh7 cells. Gene Ontology analysis showed that these differentially expressed genes (DEGs) were highly enriched for protein phosphorylation, cell cycle arrest and metabolic processes. Pathway analysis revealed that metabolic pathways were the predominant enriched pathways among the upregulated genes, while the TGF‐β and Wnt/β‐catenin signalling pathways were prominent in the downregulated clusters. Pathway interaction networks also showed that the Wnt/β‐catenin pathway was located in the centre of the cluster. The expression levels of selected DEGs were validated by qRT‐PCR, and Wnt/β‐catenin involvement was validated by luciferase assays, western blotting and immunohistochemical analysis in vitro and in vivo. These results provide a comprehensive overview of the transcriptome in GSTZ1‐1‐overexpressing Huh7 cells and indicate that GSTZ1‐1 may play a tumour suppressor role by inactivating the Wnt/β‐catenin signalling pathway.
Enhanced Thermoelectric Performance and Service Stability of Cu2Se Via Tailoring Chemical Compositions at Multiple Atomic Positions
Authors: Mao Tao , Qiu Pengfei , Du Xiaolong , Hu Ping , Zhao Kunpeng , Xiao Jie , Shi Xun , Chen Lidong
Published: November 2019

Liquid‐like thermoelectric (TE) materials have the advantages of ultrahigh performance, low cost, and environment friendly, but their stability is greatly limited by the possible Cu/Ag deposition under a large current and/or temperature gradient. The pratical application based on liquid‐like TE materials requires both a high TE figure of merit (zT) for high energy conversion efficiency and large critical voltage for good stability, but they are very difficult to be simultaneously achieved in one material. In this work, both the zT and critical voltage are simultaneously optimized in Cu2Se via tailoring chemical compositions at multiple atomic positions, i.e., introducing Cu deficiency at the Cu‐sites to lower Cu ion chemical potential and alloying sulfur at the Se‐sites to reduce carrier concentrations. A maximum zT of 2.0 at 1000 K has been successfully achieved for Cu1.96Se0.8S0.2, about a 30% improvement over that for Cu2Se. More importantly, Cu1.96Se0.8S0.2 demonstrates a much higher critical voltage than Cu2Se, yielding a greatly enhanced service stability under the conditions with/without a temperature gradient. An Ni/Mo/Cu1.96Se0.8S0.2 TE unileg is successfully fabricated with a stable power output even after 400 thermal cycles between 473 and 873 K. This study greatly accelerates the real application of Cu2Se‐based liquid‐like materials.
Amorphous Fe‐Based Nanoagents for Self‐Enhanced Chemodynamic Therapy by Re‐Establishing Tumor Acidosis
Authors: Chen Xiaoyan , Zhang Huilin , Zhang Meng , Zhao Peiran , Song Ruixue , Gong Teng , Liu Yanyan , He Xinhong , Zhao Kuaile , Bu Wenbo
Published: November 2019

Chemodynamic therapy (CDT) by introducing the Fenton‐/Fenton‐like reaction in an acidic and H2O2 environment for toxic hydroxyl radical (•OH) generation, is a newly developed tumor‐selective therapeutic. However, tumor acidosis, characterized by extracellular acidity (pHe ≈ 6.5) and intracellular alkalinity (pHi ≈ 7.2), undoubtedly confers a large chemical barrier for effective implementation of intracellular CDT and thus limits its functional activity and therapeutic efficacy. Here, the unique amorphous iron nanoparticles (AFeNPs) loaded with carbonic anhydrase IX inhibitor (CAI) are constructed to re‐establish tumor acidosis with decreased pHi and increased pHe via inhibiting the over‐expressed CA IX in cancer cells by CAI for self‐enhanced CDT. The suppression of CA IX leads to H+ accumulation in cells that could accelerate the AFeNPs‐based Fenton reaction to drastically exacerbate oxidative stress in cells and subsequently induce cell death; meanwhile, the inhibition of H+ formation outside cells efficiently represses the potential of tumor invasion and metastasis owing to the insufficient acidic ions for degradation of tumor extracellular matrix. Re‐established tumor acidosis not only assists in the optimization of CDT, but also presents an opportunity for the development of new antitumor methods that are more tumor‐acidity specific.
Enantiomeric Control of Intrinsically Chiral Nanocrystals
Authors: Hananel Uri , Ben‐Moshe Assaf , Tal Daniel , Markovich Gil
Published: November 2019

The chiral aspect of inorganic crystals that crystallize in chiral space groups has been largely ignored until recently, partly due to difficulties in characterizing the chiroptical properties of bulk crystals, and also due to the difficulty in separating (sub)micrometer‐scale chiral crystal enantiomers. In recent years, the colloidal synthesis of intrinsically chiral nanocrystals (NCs) of several chiral inorganic compounds with significant enantiomeric excess has been demonstrated. This is achieved through the use of chiral molecular ligands, which bind to the atomic/ionic components of the crystals, preferentially forming one crystal enantiomorph. Here, recent progress on several aspects of these NCs is described, including the connection between ligand structure and its ability to direct NC handedness, chiral amplification in the synthesis leading to enantiopure NC samples, spontaneous symmetry breaking, the formation of NCs with chiral shapes, the connection between lattice and shape chirality and mixed contributions of atomic‐scale and shape chirality to the chiroptical properties.
Tape‐Casting Li0.34La0.56TiO3 Ceramic Electrolyte Films Permit High Energy Density of Lithium‐Metal Batteries
Authors: Jiang Zhouyang , Wang Suqing , Chen Xinzhi , Yang Wenlong , Yao Xiang , Hu Xinchao , Han Qingyue , Wang Haihui
Published: November 2019

Ceramic oxide electrolytes are outstanding due to their excellent thermostability, wide electrochemical stable windows, superior Li‐ion conductivity, and high elastic modulus compared to other electrolytes. To achieve high energy density, all‐solid‐state batteries require thin solid‐state electrolytes that are dozens of micrometers thick due to the high density of ceramic electrolytes. Perovskite‐type Li0.34La0.56TiO3 (LLTO) freestanding ceramic electrolyte film with a thickness of 25 µm is prepared by tape‐casting. Compared to a thick electrolyte (>200 µm) obtained by cold‐pressing, the total Li ionic conductivity of this LLTO film improves from 9.6 × 10−6 to 2.0 × 10−5 S cm−1. In addition, the LLTO film with a thickness of 25 µm exhibits a flexural strength of 264 MPa. An all‐solid‐state Li‐metal battery assembled with a 41 µm thick LLTO exhibits an initial discharge capacity of 145 mAh g−1 and a high capacity retention ratio of 86.2% after 50 cycles. Reducing the thickness of oxide ceramic electrolytes is crucial to reduce the resistance of electrolytes and improve the energy density of Li‐metal batteries.
Ultrathin, High Capacitance Capping Layers for Silicon Electronics with Conductive Interconnects in Flexible, Long‐Lived Bioimplants
Authors: Li Jinghua , Li Rui , Chiang Chia‐Han , Zhong Yishan , Shen Haixu , Song Enming , Hill Mackenna , Won Sang Min , Yu Ki Jun , Baek Janice Mihyun , Lee Yujin , Viventi Jonathan , Huang Yonggang , Rogers John A.
Published: November 2019

Bioimplants that incorporate active electronic components at the tissue interface rely critically on materials that are biocompatible, impermeable to biofluids, and capable of intimate electrical coupling for high‐quality, chronically stable operation in vivo. This study reports a materials strategy that combines silicon nanomembranes, thermally grown layers of SiO2 and ultrathin capping structures in materials with high dielectric constants as the basis for flexible and implantable electronics with high performance capabilities in electrophysiological mapping. Accelerated soak tests at elevated temperatures and results of theoretical modeling indicate that appropriately designed capping layers can effectively limit biofluid penetration and dramatically extend the lifetimes of the underlying electronic materials when immersed in simulated biofluids. Demonstration of these approaches with actively multiplexed, amplified systems that incorporate more than 100 transistors in thin, flexible platforms highlights the key capabilities and the favorable scaling properties. These results offer an effective encapsulation approach for long‐lived bioelectronic systems with broad potential for applications in biomedical research and clinical practice.
Detecting Non‐Markovianity via Linear Entropy of Choi State
Authors: Zheng Xiao , Ma Shao‐Qiang , Zhang Guo‐Feng
Published: November 2019

Non‐Markovian dynamics detection is one of the most popular subjects in quantum information science. In this paper, a linear‐entropy‐based non‐Markovianity witness scheme is constructed. The positive definiteness of the Choi state will be broken in non‐Markovian evolution, which can be witnessed by its linear entropy. Thus, the linear entropy of the Choi state can be used to witness non‐Markovian dynamics. The effectiveness of the proposed method is verified using the pure dephasing channel as an example. Finally, it is shown that this method can be extended to the one based on Rényi entropy.