bluuebunny/crossref_metadata_2025 huggingface dataset:
ОБОСНОВАНИЕ ТЕХНОЛОГИЧЕСКОГО РЕЖИМА БЛАНШИРОВАНИЯ ПОЛУФАБРИКАТОВ ИЗ КЛУБНЕЙ ТОПИНАМБУРА ДЛЯ ПРИГОТОВЛЕНИЯ ЭКОСНЕКОВ
Authors: Шамкова Наталья Тимофеевна , Руденко Ольга Валентиновна , Тамова Майя Юрьевна , Варивода Альбина Алексеевна , Яковлева Татьяна Викторовна
Published: September 2022

Одной из проблем, требующей решения при переработке топинамбура, является изменение сенсорных характеристик, включая потемнение полуфабрикатов и формирование кофейного привкуса в процессе тепловой обработки. Эти нежелательные изменения связаны с окислением полифенолов и образованием соединений, имеющих темную окраску. Бланширование применяется для инактивации ферментов, изменения структуры сырья, снижения микробиологической обсемененности. Авторами исследовано влияние продолжительности и температуры бланширования в жидких средах на физико-химические показатели полуфабрикатов из топинамбура, а также на инактивацию фермента пероксидазы. Бланширование проводили: в воде (раствор № 0), в растворе 2 %-ной лимонной кислоты (раствор № 1) и в молочной сыворотке (раствор № 2) при температуре 65 °С, 80 °С и 95 °С от 3 до 9 минут. Активность пероксидазы оценивали колориметрическим методом, твердость полуфабрикатов - на приборе «Структурометр-СТ1». Спецификация модели проведена в программе Statistica с помощью бикубической сплайн-интерполяции. Получены регрессионные уравнения зависимости содержания пероксидазы и твердости полуфабрикатов из топинамбура от температуры и продолжительности бланширования в различных средах. Проведенные исследования обосновывают целесообразность бланширования полуфабрикатов из топинамбура в молочной сыворотке для получения экоснеков. Установлен оптимальный режим бланширования в молочной сыворотке: температура 80 °С, продолжительность от 6 до 9 мин. Активность пероксидазы при этом снижается на 87,0 % от первоначального значения, сохраняются нейтральный вкус и запах, цвет продукта − от молочно-белого до кремового.
ИЗУЧЕНИЕ ВЛИЯНИЯ МОРФОЛОГИЧЕСКОЙ СТРУКТУРЫ ДРЕВЕСИНЫ НА ЭКСПЛУАТАЦИОННЫЕ ХАРАКТЕРИСТИКИ ПЛИТНОГО МАТЕРИАЛА
Authors: Беушева Ольга Сергеевна , Коренева Наталья Владимировна , Беушев Александр Анатольевич
Published: September 2022

Сегодня ни одно, даже самое крупное, предприятие в области деревообрабатывающей и лесозаготовительной промышленности не использует древесину на 100 %. Отходы в виде щепы, опилок, стружки, спилов представляют собой ценный сырьевой ресурс, который можно применять для дальнейшего использования. Проблема комплексной переработки древесины в деревообрабатывающей промышленности существует с момента развития этой отрасли и остро обозначена в наше время. В статье мы предлагаем один из способов решения данной проблемы. Рассмотрена возможность получения плитного материала, изготовленного из отходов различных пород древесины. Показано влияние структуры хвойных и лиственных пород дерева на эксплуатационные показатели плитного материала. Изучено влияние давления прессования на примере самой мягкой породы дерева - тополя.
A variational quantum algorithm for approximating convex roofs
Authors: Androulakis George , McGaha Ryan
Published: September 2022

Many entanglement measures are first defined for pure states of a bipartite Hilbert space, and then extended to mixed states via the convex roof extension. In this article we alter the convex roof extension of an entanglement measure, to produce a sequence of extensions that we call $f$-$d$ extensions, for $d \in \mathbb{N}$, where $f:[0,1]\to [0, \infty)$ is a fixed continuous function which vanishes only at zero. We prove that for any such function $f$, and any continuous, faithful, non-negative function, (such as an entanglement measure), $\mu$ on the set of pure states of a finite dimensional bipartite Hilbert space, the collection of $f$-$d$ extensions of $\mu$ detects entanglement, i.e. a mixed state $\rho$ on a finite dimensional bipartite Hilbert space is separable, if and only if there exists $d \in \mathbb{N}$ such that the $f$-$d$ extension of $\mu$ applied to $\rho$ is equal to zero. We introduce a quantum variational algorithm which aims to approximate the $f$-$d$ extensions of entanglement measures defined on pure states. However, the algorithm does have its drawbacks. We show that this algorithm exhibits barren plateaus when used to approximate the family of $f$-$d$ extensions of the Tsallis entanglement entropy for a certain function $f$ and unitary ansatz $U(\theta)$ of sufficient depth. In practice, if additional information about the state is known, then one needs to avoid using the suggested ansatz for long depth of circuits.
Biological activity In vitro, absorption, BBB penetration and tolerability of nanoformulation of BT44, a RET agonist with disease-modifying potential for the treatment of neurodegeneration
Authors: Haider Malik Salman , Mahato Arun Kumar , Kotliarova Anastasiia , Forster Stefan , Böttcher Bettina , Stahlhut Philipp , Sidorova Yulia , Luxenhofer Robert
Published: September 2022

BT44 is a novel, second generation glial cell line-derived neurotropic factor (GDNF) mimetic, with improved biological activity and a lead compound for the treatment of neurodegenerative disorders. Like many other small molecules, it suffers from intrinsic poor aqueous solubility, posing significant hurdles at various levels for its preclinical development and clinical translation. Herein, we report a poly(2-oxazoline)s (POx) based BT44 micellar nanoformulation with ultra-high drug loading capacity of 47 wt.%. The BT44 nanoformulation was comprehensively characterized by 1H-NMR spectroscopy, differential scanning calorimetry (DSC), powder X-ray diffraction (XRD), dynamic light scattering (DLS) and cryo-transmission/scanning electron microscopy (cryo-TEM/SEM). The DSC, XRD and redispersion studies collectively confirmed that the BT44 formulation can be stored as a lyophilized powder and can be redispersed upon need. The DLS suggested that the redispersed formulation is suitable for parenteral administration (Dh ≈ 70 nm). The cryo-TEM measurements showed the presence of worm-like structures both in plain polymer and BT44 formulation. The BT44 formulation retained biological activity in immortalized cells and in cultured dopamine neurons. The micellar nanoformulation of BT44 exhibited improved absorption (after subcutaneous injection) and blood-brain barrier (BBB) penetration and no acute toxic effects in mice were observed. In conclusion, herein, we have developed an ultra-high BT44 loaded aqueous injectable nanoformulation, which can be used to pave way for its preclinical and clinical development for the management of neurodegenerative disorders.
Aqueous PFCA Destruction by Hydroxyl Radical at Low pH: A Putative H-atom Abstraction Mechanism
Authors: Carre-Burritt Asa , Amador Camille , Vyas Shubham
Published: September 2022

Hydroxyl radical is a potent oxidant invoked in numerous advanced oxidation processes as a species responsible for destroying recalcitrant organic contaminants. However, there has been little direct evidence for the reaction between hydroxyl radical and perfluoroalkyl carboxylic acids in the aqueous phase. Nevertheless, we discovered that at low pH, perfluoroalkyl carboxylic acids are degraded by hydroxyl radical. When perfluorobutanoic acid was treated with H2O2 under steady-state 254 nm irradiation in 1 M HClO4, it was transformed to shorter-chain perfluoroalkyl carboxylic acid homologues and F–/HF. Empirical and computational mechanistic studies suggested an H-atom abstraction mechanism. Namely, more perfluorobutanoic acid was removed as the pH was decreased, which corresponds to a larger fraction of protonated perfluorobutanoic acid vs. conjugate base. Meanwhile, density functional theory calculations indicated that single electron transfer oxidation of protonated perfluoroalkyl carboxylic acids has a much larger free energy of activation relative to single electron transfer oxidation of the conjugate base anion, suggesting that single electron transfer is unfavorable at low pH. This is the first clear description of aqueous perfluoroalkyl carboxylic acid destruction by hydroxyl radical under simple reaction conditions.
OpenPCA and Raman mapping to decipher complex spectral datasets from multi-component samples: application to cannabis trichomes
Authors: Balasubramanian Janani , Crocioni Elisa , Frattini Mattia , Hill Scott , Sands Darryen , Zanchi Chiara , Tommasini Matteo , Agarwal Nisha Rani
Published: September 2022

The development of analytical techniques that decode chemical information in complex biochemical samples to discriminate different structural components may open the way for several new findings. In this study, principal component analysis (PCA) is carried out using an ad hoc Matlab coding that provides a transparent access to multivariate analysis of Raman mapping datasets. Here, we illustrated the efficacy of this method to extract meaningful results from Raman images of Cannabis sativa trichomes. A large dataset of Cannabis trichome comprising of 441 Raman spectra was examined for the first time using our OpenPCA. By mapping the chemical distribution in the trichome, we could locate the secretary vesicles in the PC score maps generated from the mapped Raman spectra. Black-box PCA solutions available in commercial software can be limited by rigid input interfaces which may prevent obtaining information by tuning the PCA analysis on selected wavenumber ranges. Hence, the OpenPCA scripts facilitate the task of obtaining key information from widely distributed range of wavenumbers that are characteristic to a specific cannabinoid, namely Δ9-THC and CBD. Overall, the PCA-coding algorithm shows advantages in decoding Raman spectra that could be extended to handle all kinds of datasets with simultaneous spatial and chemical details.
Statistical Mechanics of Dimerizations and its Consequences for Small Systems
Authors: Zangi Ronen
Published: September 2022

Utilizing a statistical mechanics framework, we derive the expression of the equilibrium constant for dimerization reactions. An important feature arising from the derivation is the necessity to include two-body correlations between monomer's particles, reminiscent to those recently found crucial for binding reactions. However in (homo-) dimerizations, particles of the same type associate, and therefore, self-correlations are excluded. As a result, the mathematical form of the equilibrium constant differs from the well-known expression given in textbooks. For systems with large number of particles the discrepancy is negligible, whereas, for finite systems it is significant. Rationalized by collision probability between monomers, the bimolecular rate for dimer formation is proportional to concentration the same way correlations are accounted for. That is average of squared, and not square of averaged, monomer concentration should be considered in such a way that inconceivable collisions between a tagged particle with itself are excluded. Another consequence emerging from these two-body correlations, is an inhomogeneous function behavior of system's properties when scaling-down the system to a regime smaller than the thermodynamic limit. Thus, averages of properties observed at small systems are different than those observed at macroscopic systems. When applied to the size-dependent composition of the system, we further demonstrate the equilibrium concentration of the dimer (or monomer) can be obtained from only the magnitudes of fluctuations in the system. All predictions are verified by Monte Carlo and molecular dynamics simulations.
Structural and Optical Properties of Ni and Zn co-doped Copper Oxide nanoparticles
Authors: Dash Ritambhara , Bhattacharyya Arnab
Published: September 2022

Ni doping in CuO showed successful replacement of Cu+2 ions by Ni+2 ions. Evidence of strain being developed due to doping was seen. Change in crystallite size was observed depending upon the role of Ni as a nucleating center. Intensity variations in absorption and emission spectra were observed which were related to the amount of defects or formation of new phases in the materials. A wide absorption window was observed due to exciton. A change in band gap was observed corresponding to the change in particle size. Zn doping in CuO caused a variation in crystallite size and incorporated defects which had effect on the optical properties. A change in band gap due to defect generated energy levels as well as quantum size effect was seen.
Difference in the perceived safety by CPTED in school between design practitioners and users
Authors:   KOREA CPTED ASSOCIATION, Ahn Yongjin
Published: September 2022

This study aims to offer the basic information on the important design elements of CPTED in school which rationally represent user-oriented design process by quantitatively analyzing the difference in the pre/post evaluation of CPTED simulation between design practitioners and users. Results from field survey for the perceived safety from crime by various spatial units in school revealed the mean difference between design practitioners and users at the statistically significant level. In addition, there was a clear gap in the effectiveness and importance order of some CPTED elements between design practitioners and users. More specifically, access control to a secluded spot outside, installing CCTV in a secluded spot outside building, improving territoriality in parking areas, and reinforcing maintenance of indoor rest-room are highly ranked as an important design element among the users, while those are not among the design practitioners. Such evaluation gaps might represent design consideration on aesthetic impression of design practitioners. Therefore, design consideration on utilization, along with design consideration on aesthetic impression, should be reflected as the feedback from users in the design process for the substantial improvement of the performance of CPTED in school.
APLICACIÓN DEL CONCEPTO “APRENDER – HACIENDO” EN LA ENSEÑANZA DE LA INGENIERÍA INDUSTRIAL: CASOS DE ESTUDIO
Authors: Acevedo Urquiaga Ana Julia , Acevedo Suárez José Antonio , López Joy Teresita , Gómez Acosta Martha Inés , Sablón Cossío Neyfe
Published: September 2022

El contexto actual exige profesionales con habilidades de auto preparación, gestión dinámica de procesos e intenso empleo de tecnologías. El acceso a contenidos amplios y siempre disponibles, ha influido en los métodos mediante los cuales todos aprendemos y enseñamos. La enseñanza tradicional, basada en clases presenciales, se va sustituyendo por una formación dinámica que implica al estudiante en contacto directo con su campo de trabajo. Para ello se han desarrollado los conceptos de Learning by Doing; y metodologías como: Aprendizaje Basado en Problemas (ABP), Aula Invertida, Aprendizaje Cooperativo, Gamificación y Design Thinking. Estos métodos pueden influir positivamente en formar mejores habilidades, fuertes y blandas, en los profesionales. El presente trabajo ofrece una metodología general para la aplicación del concepto Aprender-Haciendo (Learning by Doing) a través de una combinación de las metodologías modernas en la enseñanza de las ingenierías. Además, se muestra la aplicación en asignaturas de Ingeniería Industrial de la Universidad Tecnológica de La Habana “José Antonio Echevarría”, Universidad Técnica de Manabí y de la Fundación Universitaria San Mateo. La investigación se basa en los métodos sintético, deductivo y dialéctico, con un fuerte componente de experimentación. El principal resultado teórico, es la obtención de una metodología de Aprender-Haciendo que combina las metodologías modernas para la enseñanza-aprendizaje de las ingenierías. En el aspecto práctico, el desarrollo de asignaturas de Ingeniería Industrial en las universidades en estudio, indican un desempeño dinámico de los estudiantes en las asignaturas abordadas. Se mejora su capacidad de autoaprendizaje, uso de tecnologías y aplicación del trabajo en equipo. Por otra parte, desarrollan capacidad de liderazgo, relaciones interpersonales, actitud positiva y tolerancia al fracaso.
DESARROLLO CURRICULAR EN EL PROCESO DE EVALUACIÓN Y ACTUALIZACIÓN DEL PROYECTO EDUCATIVO DE PROGRAMA DE INGENIERÍA GEOGRÁFICA Y AMBIENTAL DE LA UNIVERSIDAD LA GRAN COLOMBIA SECCIONAL ARMENIA
Authors: Cifuentes Wchima Ximena , Vélez Medina Bibiana , Contreras Zapata Juan Gabriel , Jaramillo Echeverry Lina María , Úsuga Jaramillo Juan Sebastián
Published: September 2022

Basados en la Guía para la evaluación y actualización de la estructura curricular, la Comunidad Académica del programa de Ingeniería Geográfica y Ambiental, a través de diferentes escenarios de encuentro, análisis y discusión, reflexiona sobre su currículo, asentados en la búsqueda permanente del mejoramiento, posicionamiento y consolidación del programa en los niveles regional, nacional e internacional, basados en las crisis y desafíos detectados y cómo estos se involucran en los procesos formativos y en el ejercicio de la profesión. Este proceso curricular ordenado y sistemático desde los niveles macro, meso y micro curricular, ha permitido el rediseño curricular del programa y, por ende, la formación de sus futuros graduados, quienes serán Ingenieros Geógrafos y Ambientales contextualizados, responsables y éticos, lo que conlleva a un análisis profundo de los avances de la Ingeniería en un mundo cada vez más globalizado, con oportunidades de trabajo colaborativo y multidisciplinar, pero también con escenarios de crisis que permiten reflexionar acerca de la función social de la profesión y la forma de enfrentarlos desde la academia. El desarrollo curricular se fundamenta en la aplicación rigurosa de la metodología de análisis de la triada, en la cual se abordan los ejes de conocimiento, contexto y perspectiva de humanidad. A través de estos ejes se hallan las principales categorías de análisis que estructuran toda la propuesta curricular: propósitos de formación, los perfiles tanto del programa como del egresado, los rasgos distintivos y valores agregados del programa, las cuencas de problematización, la investigación a desarrollar y finalmente el plan de estudios y currículos de las asignaturas. Para el presente artículo se expone el desarrollo curricular de la propuesta educativa del programa, en su componente macrocurricular.
ALFABETIZACIÓN CIENTÍFICO Y TECNOLÓGICA COMO HERRAMIENTA PARA LA ENSEÑANZA DE CURSOS TEÓRICO - PRÁCTICOS EN INGENIERÍA CON BASE EN EL MODELO DIDÁCTICO DE MALLART
Authors: Paternina Durán José Luis , Forero García Edwin Francisco , Paternina Anaya José de Jesús
Published: September 2022

En el presente trabajo se muestra la Alfabetización Científico y Tecnológica como estrategia para la enseñanza de asignaturas teórico - prácticas en ingeniería, a través de una variación del modelo didáctico de Mallart. Para ello, se toma como caso de estudio los cursos de Electrónica I y Conversión Electromagnética pertenecientes al plan de estudios del programa de Ingeniería Electrónica en la Universidad Santo Tomás. Las temáticas de “Transistor como amplificador” y “Motor de Inducción” son las escogidas para desarrollar la metodología en cada curso respectivamente. Para el desarrollo de cada temática se parte de una contextualización que ilustra unas nociones básicas. De ahí, se realiza un ejercicio práctico de laboratorio dónde el estudiante tiene un primer acercamiento con la tecnología en cuestión. En esta primera parte del modelo, los docentes guían al estudiante para que la experiencia inicial con la temática en cuestión no sea traumática. Para esto, cada docente diseña una práctica de laboratorio donde garantiza el funcionamiento de los dispositivos utilizados con el fin de que el estudiante genere un vínculo afectivo positivo con los mismos. Además de ello, el docente estructura la primera práctica de tal forma que la concepción y objetivos de la Alfabetización Científico y Tecnológica faciliten el aprendizaje de las nuevas temáticas para el estudiante. Con el fin de lograrlo, se prioriza la importancia de que el estudiante desarrolle la capacidad de resolver problemas relacionados a su entorno profesional y personal, con ayuda de los conceptos científicos y tecnológicos asociados con las temáticas a desarrollar en cada curso. Después de ello, el estudiante formula (con la ayuda de las preguntas orientadoras propuestas por el docente) los conceptos y principios teóricos que sustentan los resultados obtenidos en la práctica inicial. Por último, el docente formula una práctica adicional donde los estudiantes validan los conceptos deducidos en la fase teórica. Para evaluar el impacto de la estrategia se implementa un cuestionario (validado a través de dos instancias: pares académicos y expertos) que permita evidenciar las percepciones de los estudiantes respecto a este tipo de tecnologías para el aprendizaje de las nuevas temáticas.
LA UTILIZACIÓN DE PEDAGOGÍA PROBLÉMICA PARA EL DESARROLLO DEL PROGRAMA DE INGENIERÍA BIOMÉDICA EN LA UNIVERSIDAD ECCI- BOGOTÁ. COLOMBIA
Authors: Ruiz Suárez Erika Johana , Cano Torres Guillermo Andrés , Cruz Bernal Ingrid Mercedes
Published: September 2022

La Universidad ECCI dentro de los procesos de mejoramiento curricular para el año 2019, adopto dentro de su Enfoque Pedagógico Institucional la pedagogía problémica la cual consiste en establecer núcleos y preguntas que se derivan del contexto, las tendencias y las problemáticas de las diferentes áreas del conocimiento. El programa de Ingeniera Biomédica se articula por ciclos propedéuticos con la Tecnología en Mantenimiento de Equipos Biomédicos en modalidad presencial con una duración de 10 semestres de los cuales 5 pertenecen al ciclo tecnológico y 5 al nivel ingenieril; de acuerdo con el proceso de autoevaluación institucional se realizó una actualización curricular que dio como resultado un plan de estudios diseñado a partir de las tendencias, el contexto y las necesidades del mercado desde el nivel tecnológico e Ingenieril. Así mismo se definieron de acuerdo con los lineamientos institucionales los escenarios y preguntas problémicas a partir de la revisión de los propósitos de formación del programa, los perfiles, las demandas y necesidades del contexto nacional e internacional en la disciplina de la Ingeniería Biomédica, cabe resaltar que este trabajo se realizó de forma consensuada entre la dirección de currículo institucional, la dirección del programa, los líderes curriculares y los profesores. El resultado de este trabajo colaborativo fue la generación de las áreas disciplinares, los escenarios problémicos los cuales agrupan las temáticas establecidas en cada curso, la vinculación de los procesos de aprendizaje con los problemas reales del contexto, las líneas de investigación del programa y los resultados de aprendizaje esperados en cada una de las áreas del programa. La implementación de la pedagogía problémica en el programa ha conllevado a la generación de proyectos integradores formativos y resolutivos lo cual consolidan en los estudiantes el pensamiento crítico e investigativo y desde la planificación curricular la articulación de las funciones sustantivas, el dialogo interdisciplinar y la identificación de un eje transversal de acuerdo con el área del conocimiento.
Different parameters of topology-based wireless acknowledgements in MANETS
Authors: Thamizhmaran K.
Published: September 2022

The nodes are connected by wireless channels and form a random topology. This paper focuses on a new Intrusion Detection System (IDS), Secure-Enhanced Adaptive 3 Acknowledgment (S-EA3ACK), using Enhanced Adaptive ACKnowledgment (EAACK) with hybrid cryptography specifically designed for Mobile Ad Hoc Networks (MANET). In addition, all the aforementioned protocols are compared based on several important performance metrics such as Packet Delivery Ratio (PDR), end-to-end latency, and average power consumption across Network Simulator 2 (NS2), which are used to implement and test the proposed system. Different topology sizes and node sets were used, and the results were compared to those of some closely related IDS mechanisms.
Analysis of the Degree of Convenience of Xi'an Metro Station
Authors: Zeng Baoping , Li Yonggang , Jia Wanglong , Luo Hengbo
Published: September 2022

Urban subways have developed rapidly in recent years and has gradually become the primary choice of public transportation in big cities. Subways can effectively alleviate urban traffic congestion and improve passengers’ green travel experience, especially in the old urban areas where urban space is limited, community facilities are aging and historical features are gathered. Subways play a huge role in guiding the expansion of urban space form and improving urban landscape environment. As the only channel for passengers to get in and out of the station, the subway entrance and exit act as a bridge. It is not only the transition space between the subway station space and the urban above ground space, but also an important node for the exchange and circulation of various elements in the urban space. In this paper, the influencing factors of subway entrance and exit space environments in the old city were investigated, and relevant basis for future planning, design, and construction of subway entrances and exits were provided. Firstly, the research results and shortcomings of subway entrance and exit channels were outlined. Secondly, based on the perspective of residents and passengers, this paper uses the analytic hierarchy process to determine six first-class evaluation indexes, including safety, convenience, practicability and aesthetics. This paper constructs the evaluation system of spatial environment index of subway station entrances and exits in the old urban area of Xi’an. Lastly, according to the evaluation results, the paper puts forward the targeted optimization strategies for the current situation of the entrance and exit space environment of the subway stations in the Xi’an.
Development of Management Science from 1991 to 2021: Review of Publications Indexed in WoS
Authors: Wang Fengchen
Published: September 2022

Management is a discipline that has existed for as long as humans have, but its theoretical underpinnings are relatively new. There was already evidence of the creation and use of management ideas since 2900 BC, when Egypt was deploying over ten thousand people to build the pyramids. During the Middle Ages, the Greek, Roman, and Chinese empires all created their own versions of management theory. Modern management throughs were a 20th-century phenomenon, and management was only recognized as a formal study since the late 19th century. In this paper, the development background, thoughts and schools, existing problems, research methodology, discipline branches, and functions of management as a social science are systematically discussed and elaborated. A systematic review approach was used to summarize and analyze the 2,772,999 publications included in the Web of Science from 1991 to 2021 to find out the overall trend of publication, the published organization or institution, and the high-frequency research areas.
ЭЛЕКТРОННАЯ СТРУКТУРА, ХИМИЧЕСКАЯ СВЯЗЬ И ФАЗОВАЯ СТАБИЛЬНОСТЬ БОРИДОВ ТОРИЯ ThB4, ThB6 И ThB12
Authors: Шеин И.Р.
Published: September 2022

Первопринципными методами зонной теории с учетом релятивистских эффектов в формализме спин-орбитального взаимодействия и градиентной аппроксимации обменно-корреляционного функционала были определены для систем Th-B (структуры ThB4, ThB6 и ThB12) особенности электронных структур (полные и парциальные плотности состояний, энергетические зоны). Для этих соединений установлены параметры химической связи (заселенности орбиталей и заряды атомов по Бейдеру, Малликену и Левдину). Анализируются методом COHP заселенность кристаллических орбиталей. Найдены тенденции изменения значений энергий формирования в зависимости от парциального содержания атомов бора для этих соединений. Полученные теоретические результаты сравниваются с имеющимися литературными данными.
p-Graphs Associated with Some Groups and Vice Versa
Authors: Hatoo Nooraldeen A.
Published: September 2022

Given a finite group G with a subset where is a prime. The -graphs denoted by whose vertices are the elements of and where two distinct vertices and are adjacent if or . The algebraic structure of such -graphs has been investigated using Java programming language with NetBeans IDE. Then, a method is proposed to convert the graph structure to a group-like form.
Estimation levels of cholecystokinin, gastrin and secretin in patients with type 2 diabetes mellitus
Authors: Al-Akabi Dalal F.
Published: September 2022

A diabetic patient with diabetes mellitus experiences high blood sugar levels as a result of low insulin levels or resistance to the medication's effects. The tests were carried out at a medical laboratory using specialized kits, and the 45 patient samples and 45 healthy person samples from both sexes as a control group were dispersed based on the questionnaire form. In contrast to the non-significant rise in serum gastrin and secretin levels, the results demonstrated a substantial increase in cholecystokinin (CCK) levels between the patient and control groups and a significant increase in CCK levels according to gender, type of therapy, and disease history. In conclusion, individuals with diabetes mellitus type 2 may have aberrant blood CCK levels, which require concentration to assess the full scope of their impact on the individual.
Reading the Kürk Mantolu Madonna in a Gender Context
Authors: İLHAN Esma , GENÇ Hanife Nalan
Published: September 2022

Bu çalışmada Sabahattin Ali’nin Kürk Mantolu Madonna isimli romanının anlatı yerlemleri toplumsal cinsiyet ve feminist edebiyat kuramları açısından ele alınmış ve bu yönde bir okuma yapılmıştır. Rasim karakterinin öncelendiği ve Raif
Efendi ile tanışmasının anlatıldığı ilk bölüme eklemlenerek onunla ilişkili biçimde devam eden anlatıda romanın kendi halinde ve sessiz kahramanı Raif Efendi’nin merak uyandıran gizemli aşk öyküsü ön plana çıkar. Okurda uyandırılan
merakla Raif Efendi’nin yalnızlığının ve yabancılaşmasının sebeplerini açımlanır. Raif Efendi’nin tüm geçmişini ve sessizliğinin nedenini kendisinin kaleme aldığı siyah kaplı bir defterle öğrenen okur onun buruk aşk öyküsüyle karşılaşır.
Romanda ivme kazanan olaylar da bu noktada başlar. Toplumsal cinsiyet bakış açısıyla çözümlemeye çalıştığımız romanda kahramanların kimi yerde toplumsal norm ve kabullenmelerle uyumlu söylem ve davranışlar sergiledikleri, kimi
yerdeyse bir çatışma durumunda oldukları görülmüştür. Romanda kadın ve erkeğin toplumsal cinsiyet bakış açısına göre farklı şekillerde temsil edildiği sonucuna ulaşıldığı bu çalışmada tarama (survey) türü araştırma çeşitlerinden
betimsel (descriptive) betimleyici araştırma deseni kullanılmıştır.
Evaluation of Global Political Paradigms and National Models from the Perspective of Turkish Society
Authors: KABAŞ Tolga
Published: September 2022

Küresel ekonomide istikrarlı ekonomik büyümeyi sağlayan ve başarılı kabul edilen ulusal kamu politikası modelleri vardır. Ülkelerden bazıları örneğin, Amerika ve İngiltere gibi piyasa merkezli yani, liberal politikalar ile dünyanın
en zengin ve güçlü ülkeleri olmuşlardır. Ülkelerden bazıları ise Fransa veya Japonya, Güney Kore gibi devlet merkezli politikalar ile dünyanın en başarılı ülkeleri olmuşlardır. Bu yüzden herhangi bir ulusal kamu politikası modelinin
en iyi model olduğunu söylemek doğru olmaz. Tanzimatla birlikte Türk toplumunun kapitalistleşmesi için bu iki önemli küresel politika paradigması uygulanmaktadır. Aydınların bir kısmı liberal iktisat politikalarını Osmanlıyı kurtaracak
tek çare olarak görmüştür. Liberal iktisat politikalarının tehlikeli sonuçlar doğuracağını düşünen aydınların diğer bir kısmı ise devletçi iktisat politikalarını savunmuşlardır. Ancak, her iki politika paradigması da temelde kapitalist
bir toplum düzeninin yaratılması amacını taşımaktadır. Kurtuluş Savaşının kazanılmasından sonra yeni kurulan Türk Devleti’nin hızlı kalkınması ve sanayileşmesi için bu iki küresel politika paradigmasının uygulandığı görülmektedir.
Bu bağlamda çalışmada Türk toplumunda küresel politika paradigmalarının ulusal model üzerindeki etkileri anlatılmaktadır.
Unye Historical Mansions Re-functioned
Authors: ÖDEN Hülya YAVUZ
Published: September 2022

Karadeniz bölgesinde bulunan Ordu iline bağlı Ünye ilçesinde bulunan, korunması gereken tarihi değerlerin incelenmesi ve kentin tarihi önemi, çalışmanın konusunun seçilmesine neden olmuştur. Çalışma kapsamında, Ünye ile ilgili ve Türk
evi ile ilgili araştırmalar yapılmış, yerinde belgeleme yapılarak yeniden işlevlendirilen belirli bir alanda bulunan yapılar incelenmiştir. Ünye’nin liman kenti olması, gemiciliğin ilerlemesi ekonomik yapıyı da olumlu yönde etkilemiş,
19. Yüzyılın ikinci yarısından sonra 20. Yüzyılın ise ikinci yarısına kadar büyük konakların yapılmasına neden olmuştur. Ahşap yapım tekniği ile doğa ve topografyaya uygun birbirinin manzarasını engellemeyen yapılar inşa edilmiştir.
Günümüzde ise bu konakların yalnızca bazıları günümüze ulaşabilmiş, ulaşanlardan restore edilen konaklar ise yeniden işlevlendirilerek, müze, otel, kültür merkezi gibi işlevlerle kullanılmaktadır. Çalışmada, korunması gerekli yapıların
güncel durumlarının değerlendirme yapılmıştır. Verilen işlevler sonucunda yapıların günümüzde yaşayan insanlarının da geçmiş ile bağ kurabilmesi, atıl durumda olmaktan kurtulabilmesi bakımından yeniden işlevlendirme önem taşımaktadır.
Yapıya verilen işlev ile kültür merkezine dönüşebilmekte ya da hizmet sektörü için kullanılabilmektedir.
Exam Questions for the History of Fiqh and Usul al-Fiqh in the Curriculum of Darulfun, Dated 1915
Authors: KILIÇ Mumammed Tayyib
Published: September 2022

Tanzimat ve sonrası dönem Osmanlı Devleti’nin pek çok alanda köklü bir değişim içine girdiği bir süreçtir. Bu değişimin önemli basamaklarından biri de eğitim alanında yaşanmıştır. Osmanlı Devleti’nde modern bir yükseköğretim kurulması
yönünde çeşitli teşebbüsler olmuş ve 1 Eylül 1900 tarihinde Dârülfünûn-i Şahâne açılmıştır. Dinî ilimlerin yükseköğretim seviyesinde eğitim ve öğretiminin yapılması için de bir takım kurumlar açılmıştır. Bu kurumlardan biri olan
Dârülfünûn Ulûm-i Şer‘iyye Şubesinde fıkıh tarihi dersinin okutulması Kâmil Miras’a havale edilmiş, kendisi de bu amaçla ilk Türkçe fıkıh tarihi kitabı olan Tarih-i İlm-i Fıkıh adlı eserini kaleme almıştır. Diğer taraftan yine
Dârülfünûn fıkıh usulü hocalarından Seyyid Bey de ders notlarından derlenen Usul-i Fıkıh Dersleri adlı eserini yazmıştır. Kâmil Miras’ın Tarih-i İlm-i Fıkıh ile Seyyid Bey’in Usul-i Fıkıh Dersleri adlı eserleri dikkate alınarak
hazırlanmış olan sınav soruları bu makalenin konusunu oluşturmaktadır. Makalenin temel amacı dönemin ders kitaplarıyla uyumlu olarak hazırlanmış sınav sorularını ilgililerin dikkatine sunarak, geçmişteki fıkıh eğitimi hakkında
bilgi sahibi olmalarına imkân sağlamaktır.
The Challenges in Treating Uremic Stomatitis Patient with Chronic Renal Failure Disease
Authors: Adi Ahmad Yusuf  , Yanie Febby Martina Lefaan  , Riani Setiadhi
Published: September 2022

Background: Uremic stomatitis is a rare oral manifestation of chronic and acute kidney disease. The incidence of uremic stomatitis is low, especially because process disease develops gradually over years and occurs in advanced renal failure. This disease is associated with high levels of blood urea. There are four forms of uremic stomatitis that have been identified, namely ulcerative, erythemopultaceous, hyperkeratotic and hemorrhagic. Usually the lesions were seen on buccal mucosa, dorsal or ventral surface of tongue, gingiva, lips and floor of mouth. Purpose: To discuss the challenges in treating uremic stomatitis patient with poor systemic condition. Case: A 73 year old male patient was referred from cardiology department to oral medicine department because there were painful lesions on lips, tongue, palate and buccal mucosa. He was a chronic kidney disease patient whose laboratory results showed high urea and creatinine values. Case management: The Patient was given oral hygiene instruction to clean his teeth and tongue with a gauze soaked in NaCl at least three times a day, compressing the lips and rinse with chlorine dioxide based mouthwash (Oxyfresh®, USA) three times a day. The improvement of oral lesions were not significant because the blood urea and creatinine value were still high. Conclusion: Management of uremic stomatitis needs multidisciplinary teamwork in order to achieve the kidney function and other comorbidities improvement as well as oral lesions to improve the quality of life.
Política de segurança pública para propriedades rurais
Authors: Oliveira Carlos Antonio Ferreira de , Mara Silva Teixeira Lana , Da Silva Medina Gabriel
Published: September 2022

O crescente número de furtos e roubos contra propriedades rurais compromete a segurança dos produtores, impondo a necessidade de políticas públicas de segurança no campo. O objetivo deste estudo é analisar a experiência da Patrulha Rural Georreferenciada como política pública piloto de segurança no município de Catalão/GO. Para tanto, buscou-se apresentar a política pública, espacializar as ocorrências dos crimes, definir seus efeitos e avaliar a (in)satisfação dos residentes e trabalhadores rurais com a atuação da Patrulha Rural. O estudo foi realizado a partir de pesquisa documental nos Registros de Atendimento Integrado (RAI) do sistema da Secretaria de Segurança Pública do Estado de Goiás. Foi delimitada uma amostra de 67 propriedades vítimas de crimes patrimoniais, de um total de 2.338 existentes no município. Foram feitas entrevistas com as vítimas e com os policiais da Patrulha Rural da região. Os resultados revelam que os crimes de furtos estão concentrados nas propriedades mais próximas da zona urbana; as pequenas e médias propriedades são as que mais sofrem com os efeitos dos crimes, com redução de renda e dos investimentos; e ainda, que 91% dos produtores rurais estão satisfeitos com as ações da Patrulha Rural no município. Os crimes patrimoniais, em sua maioria o furto, causam prejuízos econômicos aos produtores, comprometendo o desenvolvimento rural. A presença estatal, nas atividades policiais preventivas e repressivas, é fundamental para a permanência do homem no campo, bem como para o desenvolvimento regional.
Desafios para a segurança pública no Maciço de Baturité – Ceará
Authors: Vasconcelos Francisco Thiago Rocha , Pontes da Silva Antonio Micael , Trajano Lopes Julimar
Published: September 2022

O presente texto aborda o aumento da mortalidade violenta no interior do Ceará tomando como objeto a situação do Maciço de Baturité e considerando dois aspectos: 1) as transformações sociais da criminalidade e das violências; e 2) o funcionamento das organizações de segurança pública e de justiça criminal. Na análise, leva-se em conta especialmente as cidades de Acarape, Barreira e Redenção, por apresentarem aumento mais expressivo da mortalidade violenta na região no período recente e por serem cidades-sede da Universidade da Integração Internacional da Lusofonia Afro-Brasileira (Unilab). Em termos metodológicos, utilizou-se de entrevistas semiestruturadas com sujeitos locais (políticos, profissionais da segurança pública e operadores do direito) e análise de dados estatísticos.
The Production of Food Commodities in Indonesia: Climate Change and Other Determinants
Authors: Hannoeriadi A. Ivan , Siregar Hermanto , Asmara Alla
Published: September 2022

Climate change has become a global issue since it has a wide range of effects on a country's socioeconomic situations, including food security. The El Nino Southern Oscillation (ENSO) is a climatic change phenomenon in Indonesia that has three phases: El Nino, Normal, and La Nina. This phenomenon has an impact on rainfall intensity, which bring another impact on the agricultural sector, particularly the sub-sector of food crops. This study uses static panel data methods to examine the impact of climate change and other determinants on food production such as rice, corn, and soybeans. The cross-sectional data are concentrated on the provinces of Java that have become the production centers of rice, corn and soybeans, and the other four provinces with the highest yields of the above three products, and the time data series used from 2009 to 2017.The results obtained show that El Nino has a significant effect on decreasing rice and corn production and increasing soybean production. While La Nina has a significant effect on increasing the production of the three commodities studied. Fertilizer subsidy has a significant effect on increasing the production of the three commodities studied meanwhile productivity significantly impact rice and corn productions.
ANALYSIS OF CASSIAVERA FARMING DEVELOPMENT STRATEGY IN KERINCI REGENCY
Authors: Ulma Riri Oktari , Nurchaini Dewi Sri , Effran Endy
Published: September 2022

The purpose of this study are describes general picture of Cassiavera farming in Kerinci Regency, and Identifying any strategies and alternative strategies that can be applied in developing Cassiavera farming in Kerinci Regency. Research data is sourced from primary and secondary data. Data collection techniques are taken by means of observation, in-person interview, and indepth interview. Determination of sample regions is done by the Stratified–Cluster random sampling method, where the technique combines stratafication and cluster methods. Meanwhile, the determination of farmer respondents was taken using the slovin technique. Data analysis in descriptive and SWOT analysis.  The results showed that the development of Cassiavera farming in Kerinci Regency uses S-O strategy which is a combination of strength and opportunity factors, with alternative strategies that can be applied, namely maintaining the quality of Cassiavera to maintain the superior advantage of Cassiavera as Indonesia's superior export commodity to meet high market demand.
NILAI - NILAI PANCASILA SEBAGAI SOLUSI MASALAH SEKULARISME DI INDONESIA
Authors: aisyah siti
Published: September 2022

Masalah sekularisme semakin marak beredar tak sedikit pemuda indonesia yang mengetahuinya akan tetapi mereka tidak memeaham artinya sehingga banyak yang tersesat dan terjerumus kedalam lingkungan yang salah, sebagai generasi penerus kita harus mempertahankan nilai nilai panasila dan mempertahankan negara indonesia agar tidak terpengaruh oleh budaya lain. Makalah ini dibuat bertujuan agar pemuda indonesia memahami arti dan makna dari sekularisme serta memahami nilai nilai yang terkandungdalam pancasila yang dapat diterapkan dalam keseharian. Metode yang digunakan penulis adalah library research yaitu mencari referensi dari buku dan juga jurnal dengan melakukan pembahasan yang terkait dengan masalah yang diajukan. Hasil dari makalah ini adalah generasi sekarang dapat memahami arti dari sekularisme yang sesunguhnya dan mengetahui nilai nilai yang terkandung dalam pancasila tidak hanya mengetahui sejarahnya saja akan tetapi nilai yang terkandung juga
Differential expression of SOX9-AS1 in amyotrophic lateral sclerosis.
Authors: Mamoor Shahan
Published: September 2022

Neurodegenerative diseases that affect the motor neurons, including amyotrophic lateral sclerosis (ALS), have little treatment options and are generally rapidly fatal (1, 2). We harnessed the power of unbiased, whole transcriptome differential gene expression analysis, utilizing primary patient cells and tissues to discover genes whose expression defines ALS using published data (3, 4). We found significant differential expression of SOX9-AS1, encoding SOX9 antisense RNA 1, in the motor neurons of patients with ALS. SOX9-AS1 was also differentially expressed in the induced pluripotent stem cell (iPSC)-derived motor neurons of patients with ALS. SOX9-AS1 transcript was present at significantly higher levels in ALS patient motor neurons as compared to control motor neurons. These analyses will begin to define the transcriptional landscape of ALS.
Differential expression of NTRK2 in amyotrophic lateral sclerosis.
Authors: Mamoor Shahan
Published: September 2022

Neurodegenerative diseases that affect the motor neurons, including amyotrophic lateral sclerosis (ALS), have little treatment options and are generally rapidly fatal (1, 2). We harnessed the power of unbiased, whole transcriptome differential gene expression analysis, utilizing primary patient cells and tissues to discover genes whose expression defines sporadic ALS using published data (3, 4). We found significant differential expression of NTRK2, encoding neurotrophic receptor tyrosine kinase 2, in primary motor neurons of patients with ALS. NTRK2 was also differentially expressed in the fibroblasts isolated from patients with ALS. NTRK2 transcript was present at higher levels in ALS patient fibroblasts as compared to control, non-diseased fibroblasts. These analyses will begin to define the transcriptional landscape of ALS.
Differential expression of DYRK3 in amyotrophic lateral sclerosis.
Authors: Mamoor Shahan
Published: September 2022

Neurodegenerative diseases that affect the motor neurons, including amyotrophic lateral sclerosis (ALS), have little treatment options and are generally rapidly fatal (1, 2). We harnessed the power of unbiased, whole transcriptome differential gene expression analysis, utilizing primary patient cells and tissues to discover genes whose expression defines ALS using published and public data (3, 4). We found significant differential expression of DYRK3, encoding dual specificity tyrosine phosphorylation regulated kinase 3, in the motor neurons of patients with ALS. DYRK3 was also differentially expressed in the induced pluripotent stem cell (iPSC)-derived motor neurons of patients with ALS. DYRK3 transcript was present at significantly higher levels in ALS patient motor neurons as compared to control motor neurons. These analyses will begin to define the transcriptional landscape of ALS.
STEEP: a remotely-sensed energy balance model for evapotranspiration estimation in seasonally dry tropical forests
Authors: BEZERRA ULISSES , Cunha John , Falente Fernanda , Nobrega Rodolfo , de Andrade João , Moura Magna , Verhoef Anne , Pérez-Marin Aldrin , Galvão Carlos
Published: September 2022

Improvement of evapotranspiration (ET) estimates using remote sensing (RS) products based on multispectral and thermal sensors has been a breakthrough in hydrological research. In large-scale applications, methods that use the approach of RS-based surface energy balance (SEB) models often rely on oversimplifications. The use of these models for Seasonally Dry Tropical Forests (SDTF) has been challenging due to incompatibilities between the assumptions underlying those models and the specificities of this environment, such as the highly contrasting phenological phases or ET being mainly controlled by soil–water availability. We developed a RS-based SEB model from a one-source bulk transfer equation, called Seasonal Tropical Ecosystem Energy Partitioning (STEEP). Our model uses the plant area index to represent the woody structure of the plants in calculating the moment roughness length. We included the parameter kB−1 and its correction using RS soil moisture in the calculation of the aerodynamic resistance for heat transfer. Besides, λET caused by remaining water availability in endmembers pixels was quantified using the Priestley-Taylor equation. We implemented the algorithm on Google Earth Engine, using freely available data. To evaluate our model, we used eddy covariance data from four sites in the Caatinga, the largest SDTF in South America, in the Brazilian semiarid region. Our results show that STEEP increased the accuracy of ET estimates without requiring any additional climatological information. This improvement is more pronounced during the dry season, which, in general, ET for these SDTF is overestimated by traditional SEB models, such as the Surface Energy Balance Algorithms for Land (SEBAL). The STEEP model had similar or superior behavior and performance statistics relative to global ET products (MOD16 and PMLv2). This work contributes to an improved understanding of the drivers and modulators of the energy and water balances at local and regional scales in SDTF.