bluuebunny/crossref_metadata_2025 huggingface dataset:
Carcinosarcoma del cuello uterino: reporte de caso y revisión de la literatura
Authors: Garzón-Olivares Carmen Doris , Cortés-Díaz Daniel Otálvaro , Angel-Müller Edith , Riaño-Castellanos Giovanni Enrique , Mora-Soto Nathalia , Acosta-Forero Bernarda Jinneth
Published: October 2018

Objetivo: reportar el caso de una paciente con carcinosarcoma del cuello uterino con sangrado intraabdominal, y revisar la literatura disponible sobre el tratamiento y pronóstico de la entidad.Materiales y métodos: se reporta el caso de una paciente de 84 años, que consultó por masa abdominal y obstrucción del tracto urinario. Durante la estancia hospitalaria presentó sangrado intraabdominal con signos de choque, por lo que fue necesario realizar histerectomía abdominal total con salpingo-oforectomía bilateral, ligadura de hipogástricas y taponamiento de cavidad pélvica como intervenciones para controlar el sangrado. El estudio histológico reportó como diagnóstico carcinosarcoma del cérvix. La paciente evolucionó de forma adecuada y fue remitida para continuar manejo por oncología. Para la búsqueda de la literatura se realizó una pesquisa en las bases de datos Medline vía PubMed, SciELO y Ovid, utilizando los términos “uterinecarcinosarcoma” “treatment “cáncer treatment” “treatmentreview” y “treatmentoutcome”. La búsqueda se limitó por tipo de idioma, pero no por año de publicación.Resultados: 19 estudios cumplieron con los criterios de inclusión y de exclusión, estas fueron predominantemente reportes de caso. El estadio clínico reportado con mayor frecuencia fue FIGO IB en cerca del 53 % de los casos, y la presentación más frecuente fue el sangrado genital acompañado de masa pélvica. Con un seguimiento promedio de 15 meses, la sobrevida para este tumor es del 17 % para las pacientes que recibieron radioterapia. El 63 % de las pacientes que recibieron cirugía como tratamiento primario permanecieron libres de enfermedad durante los dos primeros años de seguimiento, con una frecuencia cercana al 100% para este mismo periodo cuando se administró radioterapia posterior a la cirugía.Conclusiones: el carcinosarcoma de cérvix es una entidad poco frecuente, cuya manifestación clínica más común suele ser la presencia de sangrado genital acompañado de masa pélvica. Dentro  de las opciones terapéuticas disponibles para tratar esta entidad se encuentran la cirugía, la radio y la quimioterapia. No obstante, independientemente del tratamiento proporcionado, el pronóstico de sobrevida para las mujeres con esta patología es inferior al de las mujeres con carcinomas escamosos o adenocarcinomas. Se requieren estudios de alta calidad metodológica que evalúen la seguridad y la efectividad de las diferentes intervenciones para el abordaje terapéutico de esta entidad.
INNOVATION IN LEADERSHIP AND TEAM PERFORMANCE: EVIDENCE FROM INDONESIA PROPERTY AGENT INDUSTRY
Authors: Purwadita Christianto Prasetyo , Sudiro Achmad , Mugiono Mugiono , Idris Idris
Published: October 2018

This research aims to examine the role of innovation in the effects of transactional and transformational leadership on team performance at PropNext Reality Indonesia. The sample consist of 90 team members of PropNext Reality Indonesia. To examine the hypotheses and mediation variable, this research used Partial Least Square (PLS) and sobel test online. This research found that all hypotheses tested were positive and significant except the first hypothesis, transactional leadership has no significant effects on team performance. In addition, it also found that innovation can mediate the relationship between transactional or transformational leadership on team performance. These results confirmed and contradicted to the previous studies conducted.
The supply-side effect on the use of debt with very short and very long maturities
Authors: FONTAINE Patrice C. , ZHAO Sujiao
Published: October 2018

We find that the pre-documented factors influence debt maturity contingent upon credit accessibility and economic conditions. Firms reliant on bank loans avoid employing short-maturity debts even though they face severe information and agency problems. By contrast, firms with sufficient access use very short debt maturities to mitigate agency issues. When credit condition deteriorates, the former has no choice but borrow at the very short end of the maturity spectrum, whereas the latter evades refinancing risk more readily by borrowing at the end. Taken together, these findings indicate a vital role of capital supply in determining debt maturity.
Pay Dividends or Invest in Corporate Social Responsibility: Is there an Inverted-U relationship?
Authors: AROURI Mohamed , MARSAT Sylvain , PIJOURLET Guillaume
Published: October 2018

We offer new original insights on the ongoing debate about the financial determinants of CSR activities by investigating the relationship between dividend policy and corporate social performance. Based upon the stakeholder theory, we postulate that satisfying shareholder claims may lead, according to distributive justice, to serving the interests of other stakeholders through corporate social policies. However, when dividends paid are too high, the company may no longer have enough financial slack to satisfy the other stakeholders, implying that dividends are paid at the expense of corporate social policies. We thus expect a curvilinear relationship between dividend policy and corporate social performance. Using a worldwide sample of almost 7,000 observations, we find support for a U-inverted relationship, revealing an optimal amount to satisfy both shareholders and stakeholders. Our findings are robust to both social and environmental pillars, various dividend measures as well as ESG scores.
An Intrinsic Formulation of Incompressible Navier-Stokes Turbulent Flow
Authors: Sun Bohua
Published: October 2018

This paper proposed an explicit and simple representation of velocity fluctuation and the Reynolds stress tensor in terms of the mean velocity field. The proposed turbulence equations are closed. The proposed formulations reveal that the mean vorticity is the key source of producing turbulence. It is found that there are no velocity fluctuation and turbulence if there were no vorticity. As a natural consequence, the laminar- turbulence transition condition was obtained in a rational way.
A Weno-Tvd Implementation for Solving Some Problems of Hyperbolic Conservation Laws
Authors: Polo Vásquez Jhon Alberto , Caro Candezano Miguel Antonio
Published: October 2018

This work deals with a numerical implementation of a fifth order CENTRAL WENO-TVD (\textit{Weighted Essentially Non-Oscillatory-Total Variation Dimimishing}) of Haschem (2006) scheme applied to the convective terms of some hyperbolic conservation laws problems, in a volume finite framework. The WENO-TVD scheme is used to solve the 1D advection and Burgers equations. For this case is implemented two different numerical fluxes: The Lax-Friedrichs and TVD fluxes. In the TVD fluxes the schemes applied are in flux-limiter form. The schemes implemented for this flux are: Van Albada-1 (van Albada et al.,1982), van Albada-2 (Kermani et al., 2003), van Leer (Hassanzadeh, 2009) and MINMOD (Hirsch, 2007). The WENO type schemes are characterized for their high order approximation, and do not produce spurious oscilations near discontinuities, shocks and higher gradients. A third order Runge-Kutta TVD for the temporal variable is used. Qualitative and quantitative comparison are presented. The numerical solutions are computed with an in-house computer code developed in MATLAB software. In future works, it will develope a paralelization of computer code for solving systems of conservation laws, e.g. Euler equations of gas dynamics.
Therapeutic Gardens – A healing environment for optimizing the health care experience of Alzheimer’s and dementia patients: A narrative review  
Authors: Uwajeh Patrick , Polay Mukaddes , Iyendo Timothy Onosahwo
Published: October 2018

Purpose: This paper extends previous works to include the role of therapeutic gardens in the healing environment as an intervention for bettering the clinical outcomes of Alzheimer’s and dementia patients, the positive impact of healing gardens and the innovative application of technologies with nature, for promoting cognitive rehabilitation in this particular patient population.Methods: Using ISI Web of Science, PubMed, ProQuest Central, MEDLIN, Scopus and Google Scholar, a relevant literature search on the positive health implications of therapeutic gardens on Alzheimer’s and dementia patients’ in the healthcare milieu was conducted.Results: Health implication of therapeutic gardens on Alzheimer’s and dementia patients’ spans across physical, social, psychological and cognitive effects. Virtual reality (VR) technologies offer positive cognitive outcomes to Alzheimer's disease (AD) and dementia patients.Conclusion: Therapeutic gardens should be extended for speedier recovery of other patient populations. Future directions in the design of healthcare gardens with a focus on patient experience are inferred.
Modeling and Simulation of Fuzzy logic based Hybrid power for
Electrification System in case of Ashuda Villages
Authors: Hizkiel Abaraham , Lakshmi Gantasala
Published: October 2018

ABSTRACT

Ethiopia is a developing country, where majority of the population lives in rural areas without access to

electricity. 83% of the total population of the country use traditional biomass energy as a basic source of

energy. In contrast, the country is endowed with sufficient renewable energy resources which can be used

as a standalone electric energy supply system for electrifying remote areas of the country. These

resources are mainly micro hydropower and wind which can be used individually or the best combination

of one another. The application of hybrid renewable energy system has become an important alternative

solution for rural electrification program.

The Modeling and control of a hybrid PV-Wind-Hydro DG system is also addressed. Dynamic models for

the major system components, namely, wind energy conversion system, PV energy conversion system,

hydro, inverter, and overall fuzzy logic controller units are developed. Then, a simulation model for the

proposed hybrid power system has been developed using MATLAB /Simulink environment. This is done

by creating subsystem sets of the major dynamic component models and then assembling into a single

aggregate model. The overall power management strategy for coordinating and/or controlling the

different energy sources is also presented in the thesis work. Generally there are 800 households with

total electric demand of 71.6KW.To satisfy this demand 52%, 35% and 13% is to be contributed from

wind/hydro/solar respectively. To use the power economically fuzzy logic controller is used. The

controller monitors the demand and the available sources and then switches to the appropriate power

supply according to the written rules. Simulations have been carried out to verify the system dynamic

performance using a practical load profile and weather data. The result shows that the overall power

management strategy is effective and the load demand is balanced. To complete this work, a grid

extension from the closest substation has been compared with hybrid system. Cost of the grid extension is

estimated based on the data obtained from EEP office. This is done in order to compare the cost of the

designed hybrid power system against the cost of grid extension. The result shows that breakeven grid

extension distance to be 23.9km which indicates that grid extension is preferable.
SU(2) Quantum Yang-Mills Thermodynamics: Some Theory and Some Applications
Authors: Hofmann Ralf
Published: October 2018

In the first part of this talk we review some prerequisites for and essential arguments involved in the construction of the thermal-ground-state estimate for the deconfining phase in the thermodynamics of SU(2) Quantum Yang-Mills theory and how this structure supports its distinct excitations. The second part applies deconfining SU(2) Yang-Mills thermodynamics to the Cosmic Microwave Background in view of (i) a modified temperature-redshift relation with an interesting link to correlation-length criticality in the 3D Ising model, (ii) the implied minimal changes in the dark sector of the cosmological model, and (iii) best-fit parameter values of this model when confronted with the spectra of the angular two-point functions TT, TE, and EE, excluding the low-$l$ physics. The latter, which is treated in an incomplete way because of the omission of radiative effects, is addressed in passing towards future work.
Crosstalk between Autophagy and Apoptosis Modulates T-2 Toxin-Induced Toxicity in Liver Cells
Authors: Wu Jing , Zhou Yu , Yuan Zhihang , Yi Jine , Chen Jingshu , Wang Naidong , tian yannan
Published: October 2018

T-2 toxin produced by fungi of Fusarium genus is highly toxic to human and animals and has been shown to induce apoptosis in various organs/tissues. Apoptosis and autophagy are interconnected processes and these interactions are important for cellular homeostasis as well as pathogenesis. In this study, we report for the first time that T-2 toxin induced autophagy in human liver cells (L02). We showed that T-2 toxin induced the formation of acidic vesicular organelles, concordant with the time and dose-dependent alterations in LC3-phosphatidylethanolamine conjugate (LC3-II) LC3-I/II and p62/SQSTM1 suggesting an enhanced autophagic flux. The T-2 toxin-induced formation of autophagosome and lysosomal fusion was observed by expressing mRFP-GFP-LC3 in L02 cells by lentiviral transduction, and autophagosome was observed by transmission electron microcopy. We found that while T-2 toxin activated both apoptosis and autophagy, activation of autophagy appears to be a leading event reflecting the protective mechanism of cells against the insults by T-2 toxin. Activating autophagy by rapamycin (RAPA) inhibited the apoptosis while suppressing autophagy by chloroquine greatly enhanced the T-2 toxin-induced apoptosis suggesting the crosstalk of autophagy and apoptosis. In summary, our study showed that activation of autophagy protects liver cells from T-2 toxin-induced apoptosis suggesting autophagy may be targeted for prevention of the T-2 toxin-induced toxicity in human and animals.
Technoetic Aesthetics of Revelation and Transcendence: The Horse in the Mind
Authors: Moore Lila
Published: October 2018

The presentation utilizes the sensibility of technoetic aesthetics in order to demonstrate an interpretive study of imagery issuing from contemporary cultural and technological innovative products and events, such as Blade Runner 2049 and SpaceX Starman, the Tesla Roadster launch. It refers in particular to the theme of horse, horseman, and rider depicted explicitly or implied through aesthetic metaphors. These images seem to conjure current apocalyptic and revelatory meanings as well as amplify a sense of collective longings for transcendence
Unified Friction Formulation from Laminar to Fully Rough Turbulent Flow
Authors: Brkić Dejan , Praks Pavel
Published: October 2018

This paper gives a new unified formula for the Newtonian fluids valid for all pipe flow regimes from laminar to the fully rough turbulent. It includes laminar, unstable sharp jump from laminar to turbulent, and all types of the turbulent regimes: smooth turbulent regime, partial non-fully developed turbulent and fully developed rough turbulent regime. The formula follows the inflectional form of curves as suggested in Nikuradse’s experiment rather than monotonic shape proposed by Colebrook and White. The composition of the proposed unified formula consists of switching functions and of the interchangeable formulas for laminar, smooth turbulent and fully rough turbulent flow. The proposed switching functions provide a smooth and a computationally cheap transition among hydraulic regimes. Thus, the here presented formulation represents a coherent hydraulic model suitable for engineering use. The model is compared to existing literature models, and shows smooth and computationally cheap transitions among hydraulic regimes.
Paradigm on Sustainable Human Health, Environment and Petroleum-contamination: Constraints and Challenges
Authors: Chukwuma Chrysanthus
Published: October 2018

Human-generated, natural occurrences and other actions connected with the petroleum industry have contributed expansively to the contamination of numerous areas of human habitant, thus effecting overwhelming challenges and constraints to sustainable human health, development and the biosphere. The sites commonly associated include derelict pits, hydrocarbon onshore release sites, and places to where oil slicks exuding from offshore releases are blown onshore. In diverse cases, remediation is pertinent to restore the affected ambient. This is required despite the complexity and intricate pore structure and fluid trafficking trajectories of soil which are not easily amenable to remediation. Due to the complex assemblage of contaminated soil, it is necessary to conduct an encompassing site assessment by considering the potential impact of the environment and human health prior to proper selecting and implementing of a desirable remediation process. There are extant remediation methodologies which are effective and efficient for the clean up of contaminated shorelines and other petroleum-contaminated sites involving inter alia agricultural activities. There are salient variations in the techniques to expunge contaminants regarding spatiotemporal and pecuniary costs or considerations due to the gross environmental hazards entailed. This study provides for the opportunity to harness and sustain the capacity for the mitigation of untoward impacts, and induce the latitude for an enabling condition in sustainable human health, environment and development in the petroleum industry and other anthropogenic activities.
Macroscopic Observation of Soil Nitrification Kinetics Impacted by Copper Nanoparticles: Implications for Nanotechnology for Micronutrient Fertilizer
Authors: Arai Yuji , vandervoort Allison
Published: October 2018

The potential agricultural use of metal nanoparticles (NPs) for slow-release micronutrient fertilizers is beginning to be investigated by both industry and regulatory agencies. However, the impact of such NPs on soil biogeochemical cycles is not clearly understood. In this study, impacts of a commercially-available copper NPs on the soil nitrification kinetics was investigated via batch experiments. The X-ray absorption near edge structure spectroscopy analysis showed that the NPs readily oxidized to Cu(II) and strongly retained in soils with minimum dissolution (<1% of total mass). The Cu2+ (aq) at 1mg/L showed the beneficial effect on the nitrification, an increase in the rate of nitrification kinetics (Vmax). However Vmax was negatively impacted by ionic Cu at 10-100mg/L and CuNP at 1-100 mg/L. The trace metal toxicity of soil nitrifiers seems to be critical in the soil nitrification processes. Among CuNPs, the suppressed nitrification kinetics was concentration dependent at >10mg/L. The reaction products of surface oxidation such as the release of ionic Cu seem to play an important role in suppressing the nitrification process. Considering the potential use of copper NPs as a slow-release micronutrient fertilizer, further studies are needed in heterogeneous soil systems.
Sustainable Development of Socio-cultural Capital in the City Divided by Border
Authors: Wróblewski Łukasz , Dziadzia Bogusław
Published: October 2018

The article presents the concept of sustainable development of socio-cultural capital with particular emphasis of the role of cultural institutions as factors influencing their development in a human being. In the article, the concept of social capital and cultural capital have been treated as complementary to each other, which is why they have been identified as a socio-cultural capital. Sustainable development of this capital in many cities of the world meets a number of problems reflected in the quality of life of its residents. In this article, a part of the town is analyzed which, due to political decisions made at the end of the First World War, has been divided for a hundred years into Cieszyn on the Polish side of the border and Czech Cieszyn (Český Těšín). This area is an example of how historical, political, demographic and educational conditions form the basis for the quality of socio-cultural capital. It is also an example of cooperative activities between local government institutions and third sector organizations. Despite many differences between the residents of Cieszyn and Czech Cieszyn, the conducted analysis points to the formation of a socio-cultural capital of a combining character, according to how Robert Putnam wrote about such phenomena, without neglecting the diversity of goals and interaction groups.
On the Role of Large Nuclear Gravity in Understanding Strong Coupling Constant, Nuclear Stability Range, Binding Energy of Isotopes and Magic Proton Numbers – a Critical Review
Authors: U.V Satya Seshavatharam , Lakshminarayana S.
Published: October 2018

With reference to our earlier published views on large nuclear gravitational constant , nuclear elementary charge  and strong coupling constant , in this paper, we present simple relations for nuclear stability range, binding energy of isotopes and magic proton numbers.
Recycling the Gan Waste from LED Industry by Pressurized Leaching Method
Authors: Chen Wei-Sheng , Hsu Li-Lin , Wang Li-Pang
Published: October 2018

In recent years, with the increasing research and development of the LED industry which contains GaN, it is expected that there will be a large amount of related wastes in the future. Especially the gallium has extremely high value of economic, therefore, it is necessary to establish the recycling system of the GaN waste. However, GaN is a direct-gap semiconductor and with high energy gap, high hardness, and high melting point make it difficult to recycle. Therefore, this study will analyze the physical characteristics of LED wastes containing GaN and carry out various leaching method to leach the valuable metals from the waste optimally. Different acids are used to find out the best reagent for leaching the gallium. Different experimental parameters are discussed such as the effect of the different acid agents , concentration, pressure, solid-liquid mass ratio, temperature, and time which influence the leaching efficiency of the gallium. In this study, various leaching methods which effect the leaching efficiency of the gallium are compared and the advantages and disadvantages are discussed. Finally, pressurized acid leaching method is preferred to leach the GaN waste, and hydrochloric acid is used as the leaching solution because of its better leaching efficiency of gallium. Eventually, the leaching efficiency of the gallium can reach to 98%.
Structure and Conditions for the Functioning of the Polish-Czech Cross-Border Market of Cultural Services
Authors: Wróblewski Łukasz
Published: October 2018

This is a theoretical and empirical article. In the first part, an original definition of the cross-border market for cultural services has been developed, based on classic market definitions. The structure and conditions of functioning for this market have also been presented. The next part of the article discusses the supply side of the cross-border market of cultural services for the two twin towns: Cieszyn (Poland) and Český Těšín (Czech Republic). Next, based on the surveys conducted, the participation of residents of both towns in the most important cultural events organised by cultural institutions on both sides of the border was examined.
In Schizophrenia, Low Natural IgM Antibody Titers to Oxidative Specific Epitopes and Higher IgM Responses to Nitrated and Nitrosylated Proteins Strongly Predict Negative Symptoms, Neurocognitive Impairments and the Deficit Syndrome
Authors: Maes Michael , Kanchanatawan Buranee , Sirivichayakul Sunee , Carvalho Andre F.
Published: October 2018

Schizophrenia is characterized by an interrelated activation of the immune-inflammatory response system (IRS) and the compensatory immune-regulatory reflex system (CIRS), which downregulates the IRS. Deficit schizophrenia is characterized by a deficit in natural regulatory autoimmune responses to tryptophan catabolites. The presence and correlates of IgM isotype antibodies to oxidative specific epitopes (OSEs), nitroso (NO) and nitro (NO2) adducts in schizophrenia remain unknown.This study measured IgM antibodies to malondialdehyde (MDA), azelaic acid, phosphatidylinositol, oleic acid, NO-tryptophan, NO-albumin, NO-cysteinyl and NO2-tyrosine in a sample of 80 schizophrenia patients, divided into those with and those without deficit schizophrenia, and 38 healthy controls.Deficit schizophrenia was characterized by significantly lower IgM antibody levels to all OSEs as compared with non-deficit schizophrenia and controls. Lowered IgM antibodies to MDA coupled with increased IgM levels to NO-cysteinyl and NO2-tyrosine strongly predict deficit schizophrenia versus non-deficit schizophrenia with an area under the ROC curve of 0.913. A large part of the variance (21.2 – 42.2 %) in the negative symptoms of schizophrenia and excitation is explained by IgM antibody titers to MDA (inversely) and NO-cysteinyl and/or NO2-tyrosine (both positively). Lower IgM antibodies to MDA are significantly associated with impairments in episodic memory including direct and delayed recall.These findings further indicate that deficit schizophrenia is a distinct phenotype of schizophrenia, which is characterized by lower natural IgM antibody levels to OSEs and relative increments in nitrosylation and nitration of proteins. It is concluded that deficits in lowered IgM responses to MDA and azelaic acid (part of the CIRS) attenuate the negative immune-regulatory feedback on the primary immune response and that this process may drive negative symptoms and impairments in episodic memory and thus deficit schizophrenia.
Scaling Group Analysis of Mixed Bioconvective Flow in Nanofluid with Presence of Slips, MHD and Chemical Reactions
Authors: Mohd Basir Mohd Faisal , Uddin M. Jashim , Md. Ismail Ahmad Izani
Published: October 2018

Bioconvective flows have attracted attention in recent years due to actual and potential applications. In this paper, we consider a steady and laminar convective MHD flow of a nanofluid with heat, mass and microorganism transfer with a heat source/sink present. In addition, we assume there exists a first order chemical reaction. The governing partial differential equations (PDEs) are reduced to ordinary differential equations (ODEs) using the scaling group transformation and the associated boundary value problem is then solved. The influences of selected governing parameters on the dimensionless velocity, temperature, nanoparticle concentration, density of motile microorganisms, skin friction, heat transfer, mass transfer, and motile microorganism density rates are computed and discussed
Joint Power and Bandwidth Allocation for UAV Backhaul Networks: A Hierarchical Learning Approach
Authors: Yang Tingting , Yao Kailing , Sun Youming , Song Fei , Yang Yang , Zhang Yuli
Published: October 2018

Unmanned Aerial Vehicles (UAVs) severing as the relay is an effective technology method to extend the coverage. It can also alleviate the congestion and increase the throughput, especially applied in UAV networks. However, since the energy of UAVs is limited and the resources in UAV networks are scarce, how to optimize the network delay performance under these constraints should be well investigated. Besides, the relationship among different resources, e.g. power and bandwidth, is coupled which makes the optimization more complex. This article investigates the problem of joint power and bandwidth allocation in UAV backhaul networks, which considers both the delay performance and the resource utilization efficiency. Considering the heterogeneous locations characteristics of different UAVs, we formulate the optimization problem as a Stackelberg game. The relay UAV acts as the leader and extended UAVs act as followers. Their utility functions take both the delay durance and the resource consumption into account. To capture the competitive relationship among followers, the sub-game is proved to be an exact potential game and exists Nash equilibriums (NE). The Stackelberg Equilibrium (SE) is proved afterwards. We utilize a hierarchical learning algorithm (HLA) to find out the best resource allocation strategies, which also reduces the computational complexity. Simulation results demonstrate the effectiveness of the proposed method.
Anti-Nipah: A QSAR Based Prediction Method to Identify the Inhibitors Against Nipah Virus
Authors: Rajput Akanksha , Kumar Archit , Kumar Manoj
Published: October 2018

Nipah virus (NiV) is responsible to cause various outbreaks in Asian countries, with latest from Kerala state of India. Till date there is no drug available despite its urgent requirement. In the current study, we have provided a computational one-stop solution for NiV inhibitors. We have developed “anti-Nipah” web resource, which comprised of a data repository, prediction method, and data visualization modules. The database comprised of 313 (181 unique) inhibitors from different strains and outbreaks of NiV extracted from research articles and patents. However, the quantitative structure–activity relationship (QSAR) based predictors were accomplished using classification approach employing 10-fold cross validation through support vector machine with 120 (68p + 52n) inhibitors. The overall predictor showed the accuracy and Matthew’s correlation coefficient of 88.89% and 0.77 on training/testing dataset respectively. The independent validation dataset also performed equally well. The data visualization modules from chemical clustering and principal component analyses displayed the diversity in the NiV inhibitors. Therefore, our web platform would be of immense help to the researchers working in developing effective inhibitors against NiV. The user-friendly webserver is freely available on URL: http://bioinfo.imtech.res.in/manojk/antinipah/
Low-Loss Lithium Niobate on Insulator (LNOI) Waveguides of a 10 cm-Length and a Sub-Nanometer Surface Roughness
Authors: Wu Rongbo , Wang Min , Xu Jian , Qi Jia , Chu Wei , Fang Zhiwei , Zhang Jianhao , Zhou Junxia , Qiao Lingling , Chai Zhifang , Lin Jintian , Cheng Ya
Published: October 2018

We develop a technique for realizing lithium niobate on insulator (LNOI) waveguides of a multi-centimeter-length with a propagation loss as low as 0.027 dB/cm. Our technique relies on patterning a chromium (Cr) thin film coated on the top surface of LNOI into a hard mask with a femtosecond laser followed by the chemo-mechanical polishing for structuring the LNOI into the waveguides. The surface roughness on the waveguides is determined to be 0.452 nm with an atomic force microscope (AFM). The approach is compatible with other surface patterning technologies such as optical and electron beam lithographies or laser direct writing, enabling high-throughput manufacturing of large-scale LNOI-based photonic integrated circuits.
Exclusion of Dietary Cholesterol from The Specific Food Restrictions: A Review in Indonesia
Authors: Zulkarnain Mirza Rizqi
Published: October 2018

Hypercholesterolemia, the presence of high levels of cholesterol in the blood, is one of the major risk factor for cardiovascular disease (CVD). One of the key recommendation in the Dietary Guidelines for Americans 2010, is to consume less than 300 mg of dietary cholesterol per day. The same amount is also adopted in Indonesia (BPOM, 2016) until today. However, in the latest Dietary Guidelines for Americans 2015-2020, dietary cholesterol is no longer included in the list of specific foods that should be limited. The added sugars, sodium, saturated fats and trans fats remain on the list of food components that should be reduced. Generally, foods that are higher in dietary cholesterol are also higher in saturated fats. But there are also some foods that are higher in cholesterol but not in saturated fats. According to the latest recommendation, this kind of foods can be consumed without any specific restriction. In this review, some of clinical studies related to the association between dietary cholesterol and blood cholesterol levels are selected. The findings from those studies will be summarized to consider whether the same recommendation should be implemented in other countries, especially in Indonesia.
Pengaruh Teknik Pemanasan Basah dalam Pembuatan Oncom Instan Terhadap Kualitas Tumis Oncom
Authors: Zamakhsyari Imaduddin , Alsuhendra Alsuhendra , Ridawati Ridawati
Published: October 2018

Penelitian ini bertujuan untuk mengetahui dan menganalisis pengaruh teknik pemanasan basah dalam pembuatan oncom instan terhadap kualitas tumis oncom. Penelitian ini dilakukan di Laboratorium pastry, Program  Studi Tata Boga, Fakultas Teknik, Universitas Negeri Jakarta pada bulan Agustus 2016 sampai Februari 2017. Penelitian ini menggunakan metode eksperimen. Pemanasan basah teknik rebus, teknik presto teknik kukus. Data hasil penilaian panelis dianalisis dengan menggunakan uji kruskal-wallis pada taraf signifikan Î± = 0,05. hasil pengujian hipotesis dengan uji kruskal-wallis menunjukkan tidak adanya pengaruh yang signifikan terhadap mutu sensoris tumis oncom yang meliputi aspek warna, aroma, rasa, dan tekstur.
Penerimaan Konsumen Terhadap Cokelat Ganache Krim Nabati (Survei pada Pengusaha Kue di Wilayah Jakarta Timur)
Authors: Simatupang Innika Nurhabiba , Artanti Guspri Devi , Cahyana Cucu
Published: October 2018

Penelitian ini dilakukan untuk mendeskripsikan penerimaan konsumen terhadap cokelat ganache krim nabati. Uji penerimaan dilakukan menggunakan instrumen tertutup melalui berbagai aspek penerimaan, seperti; kesadaran, minat, evaluasi, percobaan, serta penerimaan, yang dilakukan kepada 50 pengusaha kue yang mengikuti acara kegiatan pendampingan wirausaha di RPTRA Jatinegara, Jakarta Timur. Penelitian ini menggunakan metode survei. Pengambilan sampel dilakukan dengan teknik purposive sampling. Teknik analisis data dalam penelitian ini menggunakan uji deskriptif. Hasil penelitian menunjukkan bahwa pengusaha kue yang berdomisili di wilayah Jakarta Timur menerima cokelat ganache nabati dilihat dari berbagai aspek penerimaan.
Pengaruh Penambahan Pure Sukun (Artocarpus communis) Pada Pembuatan Pasta Segar Fettucine Terhadap Daya Terima Konsumen
Authors: Mahdiyah Mahdiyah , Cahyana Cucu , Nurhayati Siti Nasya
Published: October 2018

Penelitian ini bertujuan untuk mengetahui dan menganalisis pengaruh penambahan pure sukun (Artocarpus  communis)  pada  pembuatan  pasta  segar  fettucine  terhadap  daya  terima  konsumen.  Penelitian dilakukan di Laboraturium Pengolahan Makanan Program Studi Tata Boga, Fakultas Teknik, Universitas Negeri Jakarta. Penelitian dilaksanakan hingga Januari 2017. Penelitian ini menggunakan metode eksperimen. Sampel dalam penelitian ini adalah pasta segar fettucine dengan penambahan pure sukun sebanyak 40%, 50%, dan 60% yang kemudian diujikan kepada 30 panelis agak terlatih yang menilai aspek warna, aroma, rasa, dan tekstur (kekenyalan). Hasil uji statistik menunjukkan bahwa penambahan pure sukun pada pembuatan pasta segar fettucine hanya mempengaruhi aspek aroma. Berdasarkan hasil uji Tukey pada aspek aroma, formula paling disukai konsumen dan disarankan adalah penambahan pure sukun sebanyak 50%. Hal ini mendukung tujuan penelitian yaitu optimalisasi penambahan sukun yang digunakan.
Sensory Quality and Calcium and Iron contents of the Products Incorporated with a Less Familiar Pseudo Cereal-Buckwheat (Fagopyrum esculentum Moench)
Authors: Adib Shumaila , Vasundhara A. V.
Published: October 2018

Buckwheat is a gluten-free valuable raw material to be used for the production of functional foods. Taking into consideration its nutritive value and potential benefits to human health, an attempt was made to explore the potentialities of buckwheat by incorporating into 9 products which are categorized according to their susceptibility of spoilage. Under perishable category, Fruit Custard (FC) was more accepted than Vegetable Upma (VU) and Laddu (L), under semi perishable category, Sweet Mathri (SM) was more accepted than Methi Thepla (MT) and Vegetable Paratha (VP) (P≤0.05) and under non perishable category, Crunchy Masala Puri (CMP) was more accepted than Moong Dal Crispies (MDC) and Khakhra (K) which are (P≤0.05) on par with basic. Shelf-life studies of sensory qualities of non perishable products (CMP, K and MDC) revealed that there was no significant difference in the sensory attributes and the products was stable for 3 weeks (21 days) indicating the presence of polyphenols which also has anti-microbial properties responsible for its long shelf life. Nutrient analysis indicated that iron was more in variations of semi perishable (SM-8.0mg) followed by perishable (L-4.3mg) and non perishable products (K-4.0mg)/100 grams, Calcium was analyzed to be more in variations of non perishable (MDC-206.6mg) followed by perishable (L-200.4mg) and semi perishable products (SM-181.6mg)/100 grams. The study thus revealed that the consumption of 50-60 grams of these developed products can meet 1/5th to 1/8th of the days recommended allowance of iron and calcium (19mg and 600mg respectively) for an adolescence Indian girl (10-12 years).
Isolation, Production and Application of Bacterial Pectinase for Industrial Use
Authors: Mohan Nayana , Prabhat Archana
Published: October 2018

Production of microbial enzymes at the industrial scale and their commercialization has gained a lot of focus and importance. Some of the industrially important enzymes from microbial origin include lipases, amylases, proteases, xylynases, pectinases etc. The objective of the study was production and application of bacterial pectinase for industrial use (clarification of fruit juices). Here the isolation of microorganism and characterization was done, then pectinase assay was performed and finally fruit juice was clarified using this enzyme. Here decayed orange peel was used as the sample and it was collected from a local market, South Kalamsseri- Cochin. The collected decayed orange part was subjected to serial dilution in order to isolate the organism. The dilutions were then plated on appropriate media (pecin agar media) and spread plate was performed. After the incubation time, colonies with zone were obtained which showed the production of pectinase enzyme. These isolated colonies were then inoculated to the petri plate containing pectin agar media and streak plate was performed. After 24 h incubation, the isolated colonies were subjected to Gram’s staining. It was Gram negative bacilli. The biochemical characterization (IMViC test) was done and VP Citrate tests were positive. Then the colonies were inoculated in Pectinase Production Broth. After 24 h incubation, the media was centrifuged for the isolation of enzymes. The enzyme assay was done by titration technique and the enzyme activity was found to be 0.78 U. This isolated enzyme was used for the clarification of apple juice and lime juice. According to the findings obtained from the study, the clarification of fruit juice by the use of bacterial pectinase is most cost effective and yield good results for industrial use.
Pharmacogenomics Testing for Postoperative Pain Optimization Before Total Knee and Total Hip Arthroplasty
Authors: Awad Mohamed E. , Padela Muhammad Talha , Sayeed Zain , Abaab Leila , El-Othmani Mouhanad M. , Saleh Khaled J.
Published: October 2018

* Only 1 study has evaluated the effect of polymorphisms on postoperative pain following total knee arthroplasty and total hip arthroplasty.

* Opioids do not produce optimal analgesia for all patients; nevertheless, the personalization of opioid selection and dosing is not commonly practiced, most likely because of the paucity of evidence with regard to clinical outcomes and opioid pharmacogenomics in patients undergoing total joint arthroplasty.

* Further clinical trials are still required to establish the reliability and efficacy of the pharmacogenomics panel tests.
Department «Metallurgy of ferrous and non-ferrous alloys»
Authors: Nemenenok B. M. , Trusova I. A.
Published: October 2018

The information is given about the history of the Department of «Metallurgy of ferrous and non-ferrous alloys», which has undergone three changes in the name:» Foundry of ferrous and non – ferrous metals « – «Metallurgy of casting alloys» – «Metallurgy of ferrous and non-ferrous alloys». The article describes the main developments made at the Department and implemented at the enterprises of the Republic of Belarus, the Russian Federation and Ukraine. The information is provided about the awards and honorary titles of employees of the Department during the existence of the Department. The specialties for which training of specialists with higher education at the I and II stages is implemented in postgraduate and doctoral studies are given. The names of the heads of enterprises, leading specialists and civil servants – graduates of the Department are provided.
Training of engineers on labor protection in technical universities of the Republic of Belarus
Authors: Lazarenkov A. M.
Published: October 2018

The educational-methodical, scientific and research activities of the Department «Labor Protection» of Belarusian Technical University (BNTU) were shown in the article. The disciplines involved in the training of engineers for Industry were briefly covered.
Reverse grooving for cross-screw reduction of tube bullets
Authors: Tamila V. A. , Liaukovich V. V.
Published: October 2018

The technology of cross-screw reduction of tube billets with reverse correction is presented. The calculation of the change in the geometry of the workpiece with a change in the feed angle is carried out. It is shown that for small feeding angles the change in geometry is insignificant, which makes it possible to conduct reverse correction of the workpiece. The calculation of parameters of reverse grooving is carried out.
Influence of parameters of impulse laser impact on the formation of the gradient of the structure of porous titanium powder
Authors: Minko D. V.
Published: October 2018

The possibility of selective laser sintering of graded porous and compactly porous structures by surface fusion of powder particles is demonstrated while maintaining a solid core, which leads to the formation of interparticle contacts in the presence of a liquid phase. The interaction of the light flux of the laser pulse with the surface of the powder particles under multiple reflection is considered. It is shown that the effect of single pulses of laser radiation leads to the formation of sintered structural elements of a powder material having a diameter approximately equal to the diameter of the focal spot. Technological regimes of pulsed laser action are established at which steady contact formation of titanium powder particles of the fractional compositions under study occurs. The possibility of obtaining powder materials with a gradient structure by controlling the parameters of pulsed laser action is experimentally demonstrated. It was found that accurate dosing of thermal energy and the number of pulses of laser radiation makes it possible to minimize shrinkage of powder layers in the absence of particle conglomeration, to control the structural characteristics and properties of products, to preserve the microstructure and phase composition of the initial materials.
Machine Learning Can Enhance and Add Jobs
Authors: Parshall Joel
Published: October 2018

The growing adoption of machine learning (ML) is creating a vast opportunity to achieve major improvements in operating and financial performance throughout industry and very much so in upstream oil and gas. Yet if change can be unsettling, the perceived change stemming from the spread of ML and its relative, artificial intelligence (AI), can feed alarming predictions about massive job losses and questions of whether there will eventually even be jobs for most of the population.

However, past major transformations such as the industrial revolution and the rise of automotive transportation generated as many jobs as they replaced and ultimately more.

While AI and ML may not exactly fit that template, the replacement of humans is generally a low priority among organizations implementing these technologies, said Ramanan Krishnamoorti, chief energy officer at the University of Houston and moderator of the symposium, “Energy, Artificial Intelligence, & Robotics: The Future of People in Energy,” held there in March.

Certain tasks will undoubtedly be replaced, including some that are highly repetitive and activities where robotics can eliminate unsafe work. But jobs will be improved and new ones created, especially if efficiency gains can translate into stronger economic growth.

Enhancing Human Judgment

“If you read a lot about machine learning and AI, you see stuff about ‘robot apocalypse, they’re going to take all our jobs’ and everything,” said David Fulford, staff reservoir engineer in exploration evaluation at Apache. “However, what we’ve found is that this technology is not better because it replaces humans but because it enhances human judgment.”

“I know it’s a big industry ‘it’ word, and there’s a lot of traction behind this,” said Vincent Dumlao, senior adviser for oil and gas at Intelie. “But fundamentally, like anything else, you have to have a good foundation of data—good data in, good data out. There is no machine learning button. You have to have a good idea of what your data are and what you want to get from your data, and then pick the proper machine learning technique to draw information from that data to make those correlations.”

And to have that familiarity with specific data sets, perceive where the data might lead, and select the appropriate technique to learn from the data will require a growing number of very well-informed humans.