bluuebunny/crossref_metadata_2025 huggingface dataset:
THE PROBLEM OF NATIONAL AND RELIGIOUS DISCRIMINATION IN THE IDEOLOGICAL POLICY OF THE THIRD REICH AND THE RADICAL ORGANIZATION ISIL
Authors: Бовдилова Светлана , Bovdilova Svetlana , Матвеева Елена , Matveeva Elena
Published: January 2019

The spread and expansion of the influence of international terrorist organizations on a global scale keep this phenomenon in the focus of academic interest. And it is not without reason that in the last few years the world’s attention has been drawn to the issue of war on terrorism and extremism, the global problems of mankind at the beginning of XXI century. The aim of this article is comprehension of the phenomenon of national discrimination that took place at the beginning of XX century in Nazi Germany in the form of Holocaust and has resurged in the activity of the Middle-East terrorist organization ISIL as means of fight against all infidels. The authors come to the conclusion that at the bottom of functioning of the Third Reich and the ISIL there are common ideological tenets concerning the methods of state establishing and the system of its further functioning. The main tools of such states are violence and physical extermination of the people on national and religious grounds as well as application of terror methods against civilian population.
Phycocyanin as a proxy for algal blooms in surface waters: case study of Ukerewe Island, Tanzania
Authors: Mchau Geofrey J. , Makule Edna , Machunda Revocatus , Gong Yun Yun , Kimanya Martin
Published: January 2019

Knowledge of the parameters that contribute to water body eutrophication is essential for proper monitoring and management of water quality for human consumption. This study assessed water quality parameters in relation to phycocyanin (PC) as a proxy indicator for harmful algal blooms (HABs). Samples were collected from 23 water sources – lakes, wells, springs and boreholes – in selected villages, for six months. Parameters measured included temperature, pH, redox potential, dissolved oxygen, electrical conductivity, total dissolved solids, nitrate nitrogen, nitrite nitrogen, phosphorus, reactive phosphate and total chlorophyll, which were related to (PC) occurrence. The PC concentration detected in Lake Victoria ranged from 5 to 58.4 μg/l above the WHO alert level and exceeded that in other water sources by almost 30 μg/l (P < 0.001). Univariate relationship between water quality parameters and PC indicates association with temperature, redox potential, total chlorophyll, nitrate nitrogen, nitrite nitrogen, phosphate and reactive phosphorus (P < 0.001). The multivariate model indicates that redox potential, nitrate nitrogen and phosphorus are significant statistically (P < 0.05). A predictive model indicates that nitrate nitrogen and reactive phosphorus contribute significantly to PC occurrence whereby unit (1 mg/l) increases in these parameters increase PC by 9.55 and 4.38 μg/l (P < 0.05) respectively. This study demonstrates that water quality parameters can be used to predict increases in PC and hence as a proxy for HABs. It remains important to be able to classify algal blooms, to understand which species are present and their potential cyanotoxin production.
Cyclodextrin modified filter paper for removal of cationic dyes/Cu ions from aqueous solutions
Authors: Li Yaoyue , Zhou Yanbo , Zhou Yi , Lei Juying , Pu Shengyan
Published: January 2019

A filter paper was functionalized with β-cyclodextrin and citric acid via esterification reaction for the removal of dyes and Cu ions from aqueous solutions. The adsorption capacity and removal performance of the modified filter paper (MFP) was investigated using static and dynamic adsorption experiments. The static adsorption data fit well the Langmuir and pseudo-second-order models, and the adsorption capacity of Methylene Blue (MB), Brilliant Green (BG), Rhodamine-B (RB) and Cu(II) over the MFP were 124.6 mg/g, 130.4 mg/g, 99.7 mg/g and 39.1 mg/g, respectively, which are much higher than the unmodified filter paper (below 2 mg/g). Even better, the decolorization performance and Cu(II) removal of MFP are remarkable in dynamic adsorption. The effluent can reach the National Standard for dyeing and finishing of textile industry of China after three cycles in a continuous filtration-adsorption system. This method provides a new pathway to achieve high efficiency removal of dyes and metal ions from wastewater.
Prospective Plant Based Anticancer Lead Molecules
Authors: Kaur Prabhjot , Sharma Vikas
Published: January 2019

Nature has been a source of a wide range of products being utilized for the treatment of
various diseases like malaria, cancer, diabetes etc. Among these, cancer is emerging as a leading cause
of deaths worldwide and the development of cross-resistance to already established drugs increases the
need for novel anticancer drugs. To discover novel anticancer molecules, it is a necessity to unearth the
molecules which can act as anticancer agents. Taking natural products in vision, phytoconstituents like
terpenoids, flavones, glycosides and alkaloids might act as a major source of lead molecules.
Considering the anticancer prospectives of phytoconstituents, different unknown lead molecules are
summarized in this review. The present review highlights the representative studies of plant-based
anticancer agents which are classified as per their phytochemical nature. Furthermore, important key
points along with important structure-activity relationships points regarding selected lead molecules are
also discussed.
Nanomedicine for Cancer Therapy Using Autophagy: An Overview
Authors: Kotcherlakota Rajesh , Rahaman Syed Tazib , Patra Chitta Ranjan
Published: January 2019

Autophagy is an intracellular biological catabolic process of mammalian cells to maintain the
homeostasis. It plays a wide role in the clearance of damaged cellular organelles, misfolded or aggregated
proteins like alpha-synuclein, β-amyloid peptides, Tau proteins and pathogens. Recent studies
have clearly demonstrated that dysfunction in autophagy leads to the development of cancer, cardiomyopathy,
chronic infection, neurodegenerative and other diseases. Therefore, modulation of autophagy
has therapeutic value to cure the diseases including cancer using external stimuli. In this context, various
researchers developed small molecules such as chloroquine, rapamycin, etc. for the treatment of cancer
through autophagy. However, these molecules possess side effects which limit their use in the clinics.
Therefore, nanomedicine approach could stand as an alternative treatment option to induce the autophagy
in cancer therapy. Several investigators developed a variety of nanomaterials which themselves
act as autophagy inducers or inhibitors. Considering this, the present review article will focus on the recent
developments of nanomedicine in the area of autophagy that have been focused on the treatment of
cancers. We also summarised the detailed mechanisms of nanoparticles mediated autophagy which
could be helpful for developing new strategies to fight against cancer. Also, the present review article
covers the current clinical status of nanomedicine and future challenges. Finally, we conclude with the
future potential role of nanomedicine for autophagy induction in the cancer treatment.
Importance of Oral Health in Pregnancy: A Mini-symposium
Authors: Priyamvara Aditi , Dey Amit K. , Bagchi Antara , Kelkar Raveena , Sharma Rajaram
Published: January 2019

Background:

It is known that hormonal imbalances during pregnancy make women more susceptible to dental problems. High levels of progesterone and estrogen during pregnancy, lead to an increased inflammatory response to dental plaque thus causing predisposing to gum diseases such as gingivitis. If untreated, gingivitis leads to chronic periodontitis which may manifest systemically in form of cardiovascular, endocrine or even respiratory disorders. Also, hyperacidity in the oral cavity due to gastric reflux and vomiting leads to decreased pH thus damaging the tooth enamel making the oral cavity more prone to tooth decay and tooth loss. Studies also show that periodontal disease can also lead to adverse pregnancy outcomes such as pre-term and low birth weight babies.

Objectives:

We sought to understand the role of oral health in pregnancy.

Methods:

We identified major articles of interest in the field of oral health in pregnancy and drafted a mini-symposium based on relevant information.

Conclusion:

Regular dental visits and cognizant efforts to sustain a healthy oral environment can help women in the prevention and treatment of dental issues during pregnancy. The paper highlights the common oral manifestations during pregnancy and their local and systemic impact on the body during pregnancy. Furthermore, it also emphasizes the importance of good oral health practices to counteract the oral complications and the significance of oral health awareness in pregnant women.
Cefdinir Microsphere Modulated Microflora and Liver Immunological Response to Diet Induced Diabetes in Mice
Authors: Patel Sweta , Mandaliya Dipeeka , Prajapati Bhumika , Kumar Sunny , Seshadri Sriram
Published: January 2019

Objective:

Gut microbiota is currently targeted for various diseases especially metabolic disorders
such as diabetes. Our strategy is to alter gut microflora via specific antibiotic to reduce load of inflammation
in the liver that increases as a result of high carbohydrate diet. Th1, Th17 and Treg are important
immune cell types which decide the type of inflammatory response. Liver is tolerogenic in nature
with low Th17/Treg ratio. In diabetics, this ratio decreases even more, and can cause liver trauma.

Method:

The present study tries to find relationship between gut flora and immune cells such as
Th1/Th17/Treg and their role in liver metabolism using diet induced diabetic mice model.

Result:

Upon alteration of flora using Cefdinir in different forms, one could help lower the level of
Treg cells thus increasing the ratio. Gut flora is strongly associated with the immunity in the liver.
Targeted alteration of gut flora helps us to restore insulin sensitivity.

Conclusion:

Colon targeted Cefdinir gives more promising results, opens colonic bacteria as target for
improving gut, liver inflammation and insulin sensitivity.
In silico Analysis of Different Signal Peptides for Secretory Production of Arginine Deiminase in Escherichia coli
Authors: Zarei Mahboubeh , Nezafat Navid , Morowvat Mohammad Hossein , Ektefaie Mohsen , Ghasemi Younes
Published: January 2019

Background:

Secretory production of recombinant protein in bacterial hosts fulfills
several advantages. Selecting an appropriate secretory signal peptide is a critical step in secretory
production of different protein. Several patents report the usage of signal peptides for secretory
production of recombinant proteins in E. coli. In silico identification of suitable signal peptides is
a reliable and cost-effective alternative to experimental approaches.

Objective:

This study was aimed to predict best signal peptides for the secretory production of recombinant
arginine deiminase in E. coli.

Methods:

In this study, 30 different signal peptide sequences were retrieved from database. The
signal peptide probability, location of cleavage sites, and n, h and c regions were predicted by
SignalP 4.1 and Phobius servers. After purging the 30 predicted secretory signal peptides, TorT,
bla, NrfA, TolB, PapC, PldA, Lpp were removed. Several physicochemical properties of the remaining
potential SPs were determined by ProtParam, PROSO II, and SOLpro servers for theoretically
selecting the best candidates.

Results and Conclusion:

Based on physicochemical properties, the signal peptides of OmpC,
OmpF, and DsbA were identified respectively as the promising candidates for efficient secretory
production of arginine deiminase in E. coli. Although the computational approach has established
itself as a basis of modern biotechnology, the experimental study is necessary to validate its results.
The criteria used in this study could be applied to other targets for recombination processes.
IMPLEMENTATION OF ELECTROCATALYTIC REACTOR AS OXIDATION UNIT FOR RESIDUAL REAGENT WASTEWATER OF TESTING LABORATORY
Authors: Mukimin Aris , Wicaksono Kukuh Aryo , Zen Nur , Purwanto Agus , Vistanty Hanny
Published: January 2019

The remaining reagent from the sample analysis process become a significant source of hazardous waste of laboratory tasting activities. Methylene blue, phenol and oil are pollutants common in the remaining reagent waste. The electrocatalytic reactor is effective oxidation units for these organic pollutants. The reactor was made for a 50 L capacity with cylindrical metal oxide as the anode. The three anode which 6 cm in diameter and 50 cm in length were paired stainless cathode with the distance of 2.5 cm. The reactor was also equipped with a stirrer that is connected to the motor so that the mass transfer and oxidizing agents is more effective. The reactor application was carried out by feeding the remaining reagent waste into the electrocatalytic unit and giving DC potential 5 Volt.  Each COD content for reagent waste of detergent: 2864 mg/L, phenol: 838 mg/L and oil: 708 mg/L. The reactor has reduced COD to 2157 mg/L (detergent), 399 mg/L (phenol) and 506 mg/L (oil) for 120 minutes. The high COD content in residual is caused by solvent (chloroform or hexane) that used at extraction step in determining the process of a sample. This compound is tough to oxidize into CO2 by OH radical or hypochlorite acid formed at the anode during the electrolysis process
Influence of Operational Condition on the Performance of Halotolerant Enriched - Activated Sludge System for Treating Medium Salinity Peanut Roasted Wastewater.
Authors: Yuliasni Rustiana , Setianingsih Nanik Indah , Wicaksono Kukuh Aryo , Harihastuti Nani
Published: January 2019

This research aimed to investigate the influence of operational condition on the performance of halotolerant enriched - activated sludge system for treating high organic wastewater with medium salinity from roasted peanut industry. Roasted peanut wastewater with VLR ranged from 0.268 to 4.7 kg COD/m3.day and Chloride concentration ranged between 1582 - 4392 mg/L was treated continuously for almost 77 days. Two identical reactor with Volume 25 L, namely R1 a conventional Activated Sludge (AS) System and R2, a halotolerant enriched-AS.  Both reactors were running with operational condition: HRT (9 h to 46 h) and MLSS (1000-6000 mg/L). Compared to conventional AS system, Halotolerant enriched-Activated sludge system could remove average of 86.7% COD, compared with conventional AS which was 85.7%. Average COD effluent of Halotolerant Enriched-Activated Sludge was also considerably lower, which was 127 mg/L, than conventional AS which was 150 mg/L. Halotolerant enriched-activated sludge also produced less sludge, giving a high F/M ratio (4.9) compared with conventional AS (3.5). In order to make  effluent fulfilled stream standard regulation (at central java region COD was150 mg/L), the favorable operational condition for both reactors would be at VLR 0.268 to 2.03 kg COD, HRT was 25 hours HRT,  with MLSS was 2584 – 3956 mg/L and maximum chloride concentration 1920 mg/L.
Correction of Foot Deformities using Triple Arthrodesis and Its Effect on Soft Tissue Blood Supply at Surgical Site in Patients with Cerebral Palsy
Authors: Leonchuk S. S. , Shchurova E. N. , Popkov D. A. , Chibirov G. M. , Bidiamshin R. R. , Gatamov O. I.
Published: January 2019

The aim of the study is to evaluate the efficiency of triple arthrodesis of foot and its effect on soft tissues blood supply at the surgical site during simultaneous correction of segment deformity in patients with cerebral palsy.Material and Methods. The present study reflects the authors’ experience of triple arthrodesis for correction and stabilization of foot multicomponent deformities of varying severity in 75 patients (136 feet) with cerebral palsy (IIIV level by Gross Motor Function Classification System (GMFCS)) treated in the Ilizarov center in the period from April 2012 to December 2016. The average age of the patients was 16.4±4.3 years (from 11 years 8 months to 43 years 3 months). All patients included into the study had severe arthrosis of hind and midfoot. The main option of foot fixation in this group of patients was internal fixation (elastic threaded wires, compression screws) together with plaster cast immobilization for 6–8 weeks. All patients underwent average of 4.59 surgical elements during a procedure as part of simultaneous multilevel interventions. The blood supply at the surgical site was evaluated by laser and high-frequency Doppler flowmetry before and after all stages of the surgery.Results. Long-term outcomes were evaluated at the average of 19 months after the surgery in 56 (74.7%) patients. 37 patients (66.1%) demonstrated good treatment outcomes and 19 patients (33.9%) — satisfactory outcomes. No unsatisfactory outcomes were observed. The clinical outcome of foot surgery was evaluated using the Angus-Cowell criteria. The obtained significant x-ray enhancement was maintained at the control stages of the follow up. Despite large simultaneous correction of foot deformity, there was no decrease in the parameters of microcirculatory blood supply of the skin, muscles and subcutaneous fat of the foot. The authors observed a stabilized or an increased perfusion of soft tissues.Conclusion. Triple arthrodesis for correction of foot deformities in patients with cerebral palsy and severe arthrosis in hind and midfoot is an efficient method which allows to correct and stabilize gained position of segments. The data of physiological research testify the sparing approach of such procedure and a possibility of an earlier weight-bearing on operated limb.
Penggunaan Modul MMFE untuk Meningkatkan Efikasi Diri Bahasa Inggris Siswa SMP
Authors: Hidayah Arfi Nurul , Alsa Asmadi
Published: January 2019

The differences of subject load and limited ability of students in learning English give uncertainty to student of class VII in studying it. Uncertainty themselves (self-efficacy) could decrease the willingness of the students to gain expected achievement. This study aims to examine the effect of using Mind mapping Module for English (MMFE) in improving student's English self-efficacy on class VII. This research is a module validation through the method of quasi experimental design with untreated control group design with pretest and posttest dependent samples. The subjects were 31 students of class VII. Collecting data using english self-efficacy scale, comprehension test as manipulation checks, and MMFE module. Aiken's V statistic test was used to test the validity coefficient contents of module, while the mixed anova test was used to test the effect of MMFE module towards english self-efficacy. The result showed MMFE module valid by content and empiric to improving english self-efficacy of class VII students (F=5,433, p<0,05).
What Could the Big6 Strategy Do to Students’ English and Information Literacies?
Authors: Diem Chuzaimah D. , Yuniarti Nova T. , Mirizon Soni
Published: January 2019

This study was aimed to investigate what the Big6 strategy could do to the development of both students’ proficiency in English literacy and information literacy. To achieve the purpose, an experimental study with time series design was conducted. Forty-five students of a private secondary school in Palembang were randomly selected for intervention based on their levels of reading. To collect the data, both English literacy and information literacy tests were given to the students. The results of paired-sample-t test analysis show that both students’ English and information literacies improved significantly. However, the students’ level of English Literacy was only a little bit above average and their information literacy was proficient. When regression analysis was used, only students’ speaking skill of English Literacy and the ethics aspect of information literacy contributed the least to the total achievement of each variable. These imply that the Big6 strategy is able to make a difference in students’ English and information literacies. It also deserves to be used in ELT classrooms in the future for students to enhance their English literacy including their oral expression skill and to familiarize themselves with ethical aspect of information literacy from their puberty.
DEVELOPMENT AND VALIDATION OF UV-VIS SPECTROSCOPIC METHOD OF ASSAY OF CARBAMAZEPINE IN MICROPARTICLES
Authors: Mawazi Saeid Mezail , Hadi Hazrina A. B. , Al-mahmood Sinan Mohammed Abdullah , Doolaanea Abd Almonem
Published: January 2019

Objective: This study aimed to develop a new, rapid, robust, effective, inexpensive, and accurate UV-Vis method for the quantification analysis of carbamazepine (CBZ) in the carbamazepine-loaded microparticles.Methods: CBZ was encapsulated in ethyl cellulose microparticles by a solvent evaporation method using polyvinyl alcohol (PVA) as a stabilizer. Methanol was used to dissolve CBZ followed by dilution with distilled water as diluent. CBZ drug, excipients, and microparticles were subjected to specificity, solution stability, linearity, precision and accuracy to confirm and ensure the validity of this method.Results: The results showed no interference from the excipients in the selected wavelength 286 nm. It was exhibited linearity in the range 2-12 μg/ml with R2 = 0.9992. CBZ solution was stable during 24 h. Accuracy and precision were within the accepted limits (100±2%). All results were in accordance to the ICH-Q2 guideline.Conclusion: As a conclusion, CBZ could be quantified from loaded EC microparticles using UV-Vis spectrophotometer at 286 nm. Therefore, this method can be used for the quantification analysis of CBZ in CBZ-loaded microparticles can be utilized also as an alternative method to calculate CBZ in different dosage forms.
DEVELOPMENT AND CHARACTERIZATION OF TRANSDERMAL DELIVERY SYSTEM OF DOXAZOSIN MESYLATE
Authors: Kulkarni Madhur , Hastak Vishakha , Jadhav Supriya
Published: January 2019

Objective: The study involved development of transdermal delivery system (TDDS) of doxazosinmesylate (doxa) to achieve effective systemic delivery of the drug.Methods: TDDS of doxa was prepared using hydroxypropyl methyl cellulose (HPMC) K100LV and polyvinyl pyrrolidone (PVP) K30 in 3:1 ratio solvent casting method. The formulation was evaluated for folding endurance, moisture uptake, pH, drug content and in vitro permeation. Various permeation enhancers were incorporated at 5% w/w concentration into the patch formulationto study their impact on the drug permeation. The TDDS made with Transcutol® as an enhancer was subjected to accelerated stability studies and in vivo skin irritation studies.Results: The developed TDDS showed folding endurance of 170, moisture uptakeof 15.7%, pH of 6.3, and drug content of 99±1.1% and 66% in vitro permeation of doxa over 24h. The effect of various enhancers expressed in terms of average flux can be summarized as Transcutol® (10.6±2.1 µg/cm2h)>dimethyl sulfoxide(10.17±1.2 µg/cm2h)>benzyl alcohol (9.55±1.3 µg/cm2h)>no enhancer (8.86±1.1 µg/cm2h)>dimethyl isosorbide (8.21±1.5 µg/cm2h)>Isostearic acid (7.82±1.4 µg/cm2h)>propylene carbonate (7.67±1.4 µg/cm2h)>oleic acid (7.12 µg±0.8/cm2h). The formulation was found to be stable during the accelerated stability studies. In vivo studies indicated absence of skin irritation effect the TDDS containing Transcutol®.Conclusion: TDDS of doxa comprising HPMC K100LV and PVPK30 in the ratio of 3:1 and 5% Transcutol® could serve as a potential TDDS in the treatment of benign prostatic hyperplasia (BPH) and hypertension.
SIMULTANEOUS TRACE LEVEL DETERMINATION OF BENZENE AND 1, 2-DICHLOROETHANE BY GC-HS/GC-MS IN SEVERAL PHARMACEUTICAL DRUG SUBSTANCES
Authors: Sultana Sayeeda , Nagarajan Balaji
Published: January 2019

Objective: We herein report the simultaneous trace level determination of benzene and 1,2-dichloroethane in several active pharmaceutical substances by GC-HS (gas chromatograph-head space) using a DB-624 column.Methods: This GC-HS method was developed based on an oven-programmed approach using nitrogen gas as the mobile phase. Our method is also compatible with the GC-MS (gas chromatography-mass spectrometry) technique using helium as the mobile phase instead of nitrogen. The successful separation of benzene and 1,2-dichloroethane was established by confirmation of their corresponding specific molecular masses.Results: The retention time of benzene and 1,2-dichloroethane were found to be 34.8 min and 35.6 min, respectively. The linearity was found in the range of concentration of 0.63-4.22 ppm and 1.49-9.96 ppm for benzene and 1,2-dichloroethane. The detection limit and quantification limit for benzene were 0.2 and 0.6 ppm, while those of 1,2-dichloroethane were 0.6 ppm and 1.5 ppm. These values were calculated using our developed method with respect to the test concentration of 500 mg/ml. The recovery of benzene and 1,2-dichloroethane were found to be 89–110% and 91–105%, respectively for the various pharmaceutical drug substances. The specificity of the method was studied using 20 solvents which include benzene and 1,2-dichloroethane.Conclusion: We expect that our method will be applicable for the simultaneous trace level determination of benzene and 1,2-dichloroethane during the control of manufacturing processes, and for use in rapid analysis for quality control in the pharmaceutical industry. Finally, this method was validated according to the International Conference on Harmonization (ICH) Validation Guidelines Q2 (R1).
CINNARIZINE LIQUID SOLID COMPACTS: PREPARATION EVALUATION
Authors: Sisinthy Sreenivas Patro , Selladurai Shubbaneswarei
Published: January 2019

Objective: The objective of this research was to formulate cinnarizine tablets using the liquid-solid compact technique to enhance its solubility and dissolution rate.Methods: Cinnarizine liquid-solid compacts were formulated using propylene glycol as the non-volatile solvent, Neusilin US2 as the carrier material, Aerosil 200 as the coating material and croscarmellose sodium as the disintegrant. The interaction between drug and excipients were characterized by Fourier-transform infrared spectroscopy (FTIR) and differential scanning calorimetry (DSC) studies. Different batches of liquid, solid compacts were prepared by using varying carrier-coating excipient ratio and different concentration of liquid medication. Flow parameters such as bulk density, tapped density, Carr’s Index, Hausner’s Ratio as well as an angle of repose were used to test the flowability of the powder blend. The liquid-solid compacts were produced by direct compression method and were evaluated for tests such as weight variation, drug content, hardness, thickness, friability, wetting time, disintegration time as well as the in vitro dissolution studies.Results: The results of the preformulation studies of liquisolid compacts showed acceptable flow properties. The results of FTIR and DSC studies showed that there is no drug-excipient interactions. The different R values and concentrations were found to have a marked effect on the dissolution profile. Formulations with higher carrier: coating ratio (R-value) and lower drug concentrations displayed a better dissolution profile. The percentage of drug release of F3 with an R-value of 20 and a drug concentration of 10% was found to be 88.11% when compared to the conventional marketed tablet which released only 44.07% at the end of 2 h.Conclusion: From this research, it is inferred that liquid-solid technique is a promising and effective approach that can be used to enhance the dissolution rate of cinnarizine.
CARACTERIZAÇÃO DO TRAUMA EM VÍTIMAS SUBMETIDAS A PROCEDIMENTOS CIRÚRGICOS EM UM HOSPITAL PÚBLICO DA BAHIA
Authors: Brandão da Silva Bruna , Moreira de Almeida Rios Felipe , Dourado Araújo Thereza Cristina , Arraes Paz Maria do Socorro , Silva Gomes Xavier Aline , Santa Bárbara da Silva Silvone
Published: January 2019

O objetivo deste estudo é caracterizar o trauma em vítimas submetidas a procedimentos cirúrgicos em um hospital público do estado da Bahia, Brasil. Trata-se de um estudo descritivo, de corte transversal, com abordagem quantitativa, realizado com vítimas de traumas submetidas a procedimentos cirúrgicos, admitidas no período de abril a junho de 2013 em um hospital público do interior do estado da Bahia. Os dados foram coletados em prontuários, por meio de um formulário estruturado. Os resultados mostraram que 81,4% eram do sexo masculino, 35,9% eram jovens com idade entre 18 e 28 anos e 65,6% eram solteiras. Com relação ao tipo de trauma, 79% das vítimas desenvolveram um único tipo de trauma, com predominância do trauma de extremidades (47,7%) e 21% tiveram politrauma. O principal mecanismo do trauma foi o acidente motociclístico (30,8%); 92,8% do total das vítimas foram submetidas a um procedimento cirúrgico; dentre as cirurgias realizadas, 40,3% foram ortopédicas, seguida de 23,8% torácicas. Concluiu-se que o principal tipo de trauma em vítimas submetidas a procedimentos cirúrgicos em um hospital público do estado da Bahia foi o de extremidades, sendo os acidentes de trânsito e a violência interpessoal as causas mais frequentes.

Palavras-chave: Traumatismo múltiplo. Ferimentos e lesões. Cirurgia. Epidemiologia.
CONSTRUÇÃO DE PROTÓTIPO PARA SISTEMATIZAÇÃO DA ASSISTÊNCIA DE ENFERMAGEM EM UMA UNIDADE DE CUIDADOS SEMI-INTENSIVOS
Authors: Barbosa Moura Tayse , Santa Barbara da Silva Santos Leonardo , Brandão Soares Eula Priscila , Santa Bárbara da Silva Silvone
Published: January 2019

O processo de enfermagem é o instrumento metodológico utilizado para o processo de cuidar e a Sistematização da Assistência de Enfermagem implica na organização e execução desse processo. Este artigo tem como objetivo construir um protótipo-software para implantação da Sistematização da Assistência de Enfermagem em uma unidade de cuidados semi-intensivos de um hospital público da Bahia. Trata-se de uma pesquisa de intervenção, que busca modificar a realidade estudada, explicando os problemas e propondo soluções. Os resultados apontam que a prática de enfermagem inserida no contexto das práticas em saúde, enfrenta o desafio cotidiano de imprimir uma nova lógica à organização do trabalho, configurando um agir pautado na integralidade. Concluiu-se que a utilização de um software para implantação da Sistematização da Assistência em Enfermagem em um hospital público da Bahia irá facilitar a organização do trabalho da equipe de enfermagem, melhorando a qualidade da assistência prestada ao indivíduo.

Palavras-chave: Software. Processo de enfermagem. Cuidados de enfermagem.
Distribución potencial de Musca domestica en el municipio de Jesús María, Aguascalientes, con el uso de escenarios de cambio climático
Authors: Meraz Jiménez Antonio de Jesús , López Santos Armando , García Munguía Carlos Alberto , Torres González Jorge Alejandro , García Munguía Alberto Margarito
Published: January 2019

M. domestica es el mayor parásito doméstico que causa descomposición de alimentos y actúa como vector de más de 100 patógenos para la medicina humana y veterinaria, tiene una cercana asociación con el hombre y su ambiente. El objetivo del presente estudio fue evaluar el desarrollo de M. domestica a diferentes niveles de temperatura y humedad relativa y determinar su potencial incidencia en el municipio de Jesús María, Aguascalientes. El estudio se desarrolló en el Centro de Ciencias Agropecuarias de la Universidad Autónoma de Aguascalientes (CCA-UAA), que presenta un clima semiseco templado (BS1k) con promedios anuales de temperaturas y precipitación de 16 a 18 °C y 500 a 600 mm, respectivamente; se evaluaron seis tratamientos con diferentes temperaturas y humedad relativa. Los resultados se analizaron en un diseño completamente al azar y mediante comparación de medias de Tukey (α=0.005). Los resultados muestran que la mosca doméstica se puede desarrollar a temperaturas ambientales de 20 a 30 °C; y con base en el modelo CNRMCM5 (RCP4.5) en diferentes horizontes de tiempo cercano (2015-2039), medio (2040-2060) y lejano (2090) de escenarios de cambio climático, la mosca tendrá una duración de alrededor de tres meses para el horizonte cercano y de cinco meses para el medio y lejano. Con estos datos se provee información importante que permite planear el desarrollo de estrategias para su prevención, monitoreo y control.
La calidad sanitaria del chorizo rojo tradicional que se comercializa en la ciudad de Toluca, Estado de México
Authors: Becerril Sánchez Ana Laura , Dublán García Octavio , Domínguez-López Aurelio , Arizmendi Cotero Daniel , Quintero-Salazar Baciliza
Published: January 2019

El chorizo rojo tradicional que se comercializa en Toluca es un producto cárnico con gran fama pero, poco se sabe sobre su calidad. El objetivo de este estudio fue determinar la calidad sanitaria de este embutido en diversos puntos de venta. A partir de tres muestreos, se analizaron 75 muestras de los cuatro principales mercados de la ciudad de Toluca y 10 carnicerías especializadas. Con base en normas oficiales mexicanas se determinaron: aw, humedad, pH, acidez y contenido de nitritos. Se realizó el conteo de bacterias mesófilas aerobias (BMA), bacterias ácido lácticas (BAL), coliformes totales y coliformes fecales; así como la detección de Salmonella spp. y Escherichia coli. El chorizo rojo tradicional no presentó diferencias significativas (P>0.05) en la mayoría de las variables fisicoquímicas y microbiológicas analizadas. Mostró un aw superior a 0.95; humedad entre 40 y 50 %; pH inferior a 5 y nitritos por debajo de los límites máximos (156 mg/kg) permitidos según normas oficiales mexicanas. El recuento de BMA fue entre 7.3 a 7.8 Log10 UFC/g y 7.8 a 8.1 Log10 UFC/g para BAL; coliformes totales entre 11.1 a 48.6 número más probable, NMP/g y coliformes fecales entre 4.9 a 9.7 NMP/g. La presencia de Salmonella spp. y E.coli spp. se  detectó tanto en mercados como en carnicerías especializadas, independientemente de su naturaleza; y el porcentaje de incidencia varió entre 11.1 a 60 % y 16.7 a 43.3 %, respectivamente. El chorizo rojo tradicional de Toluca presenta características distintivas, pero es imperativo implementar programas de manejo higiénico-sanitario durante su producción, almacenamiento y comercialización, que garanticen la obtención de un embutido no sólo típico de la región, sino inocuo.
Phonological consciousness and lecturing of third grade students of primary basic education
Authors: Montes Rotela Marivel , Quessep Tapias Ivon Patricia , Redondo Martínez Lizbeth María , Lastre Meza Karina Sofía
Published: January 2019

This investigative study wanted to determinate the relationship between the phonological awareness and the reading – writing process in 3th grade students from an EBP school in Sincelejo. The used instruments were the Prueba de Procesamiento Fonológico to seize the phonological awareness and the PROLEC and PROESC batteries, to measure the reading – writing process. The chosen sample were 55 students (ages 8 – 10) who were the result of previous assessments on hearing, visual and cognitive competences. The data processing was processed through an analysis using the IBM statistical package SPSS 23.0.0.0 (2015), based on the tests made by Kolmogorov–Smirnov and on Pearson’s correlation. The results show a highly relevant relationship between the phonological awareness and the output in reading – writing process.
The role of landscape design in Smart Cities
Authors: Mozuriunaite Skirmante
Published: January 2019

Smart cities are not a new phenomenon and it is an interdisciplinary definition that became a popular labeling for modern cities. However, there a is surprisingly little academic research in urban design and planning field that discusses this phenomenon. Smart cities definition is similar to intelligent, creative, sustainable or liveable cities which appears to be considered as a part of a play with words. In most of the technological and social science articles smart cities refer to a smart urban management and development via technologies and infrastructure. Based on the scientific literature overview, there are several factors affecting the city smartness, such as technology, people and communities, economy governance, planning and infrastructure. Overall there is a little information and research on urban design principles and tools in the smart city’s creation and contribution to its smartness. The most important thing is to clarify the urban design, planning and landscape design role importance to a smart city context and vice versa. The aim of this paper is to overview the smart cities concept from urban design perspective to find and highlight the important touch points, relation and role of urban design, planning and landscape design in smart cities creation. This would lead to the robust principles for smart European cities that would enable to achieve sustainable development, efficient urban growth and a better urban landscape.
GIS and AHP based modeling for landfill site selection (case study: west side of Mosul city)
Authors: Faisal Raid , Ahmed Mohammed
Published: January 2019

The accumulation of large quantities of solid waste inside Mosul city becomes a real residential and municipal management problem. There are many reasons including the existence of unplanned dumping sites within the city boundaries, and the absence of scientific researches which applies modern techniques for selecting the optimal solid waste landfill. This study uses geographic information system (GIS) and analytic hierarchical process (AHP) which is used to extract the weights with the help of Super Decision SD software. The studied variables data can be classified according to specified processing method into two types: continuous data, and discrete data. The ranking map has been designed after multiplying each variable with its extracted weight, then the final map has been created based on the values obtained from the ranking map. The results show that the optimal landfill area is located at south west Mosul city. This study aims at building a model by using GIS to determine the optimal and potential solid waste landfill site.
Optymalizacja procesu projektowego stałych urządzeń gaśniczych gazowych za pomocą metod numerycznych CFD
Authors: Boroń Sylwia , Kubica Przemysław
Published: January 2019

Computational fluid dynamics (CFD) is a modern tool used in engineering practice that can be used to optimize the design of fixed gaseous extinguishing systems (FGE-systems). The paper presents selected possibilities of practical application of numerical methods for evaluation of individual FGE-systems design parameters. The main feature of CFD modeling is the ability to obtain gas concentration distributions, flow directions of fire extinguishing mixture in a protected room and spatial distribution of air temperature, which is an important cognitive value of this method. The results show the potential for practical use of CFD methods in the modeling of extinguishing gas protection of real properties.
Barreras organizacionales en la gestión del conocimiento: consultorios odontológicos y el manejo de los RPBI / Organizational barriers in knowledge management: Dental offices and the handling of DBIW
Authors: Audiffred Valdes Alicia Ibone , Rico Rodríguez Miguel Ángel
Published: January 2019

La gestión del conocimiento es un trabajo fundamental en toda organización porque es el proceso que permite fundamentar el adecuado manejo de las actividades dentro de las empresas. Por tal motivo, el propósito de este trabajo fue identificar y analizar las barreras organizacionales en la gestión del conocimiento para el manejo de residuos peligrosos biológicos infecciosos en 60 consultorios odontológicos en Querétaro. Para ello, se aplicó a odontólogos que trabajaban en los consultorios seleccionados una encuesta constituida por 30 preguntas, la cual obtuvo una valoración α de 0.89. Los parámetros analizados fueron adquisición, uso y transformación del conocimiento, así como otros aspectos generales de los consultorios. Los resultados más relevantes fueron los siguientes: 18 % de los consultorios invierte en la adquisición del conocimiento sobre el manejo de los residuos, de modo que falta capacitación continua de los encargados, ya que solo se les capacita en la inducción; asimismo, 60 % no maneja información a través de la red, 72 % no realiza innovación y 67 % no dispone de manuales de procedimientos; además, solo 45 % está dispuesto a compartir su conocimiento. Basados en estos datos, se sugiere fomentar la cultura organizacional, así como el interés y el compromiso con el medioambiente con la finalidad de minimizar el riesgo de contaminación.
Penentuan Struktur Bawah Permukaan Daerah Geotermal Menggunakan Metode Geomagnet dan Geolistrik
Authors: Ritonga Wahyu Azhar , Kadri Muhammad
Published: January 2019

Abstrak Telah dilakukan penelitian tentang Penentuan Struktur Bawah Permukaan Daerah GeothermalMenggunakan  Metode Geomagnet Dan Geolistrik Di Dusun Bahoan Kecamatan Silau Kahean Kabupaten Simalungun. Penelitian ini bertujuan untuk mengetahui kontur penyebaran fluida, penampang anomali dan model lapisan struktur bawah permukaan. Pengukuran metode geomagnet menggunakan PPM (Proton Precession Magnetometer) tipe Elsec 770, pengambilan data dilakukan secara acak dengan jumlah titik yang diperoleh 40 titik ukur, pengolahan data  menggunakan surfer 10 untuk mendapatkan peta kontur dan Mag2DCfor windows untuk mendapatkan penampang anomali magnetik. Metode geolistrik menggunakan alat Ares-G4 Versi 4,7 (Automatic Resistivity System) dan GPS (Global Position System) pengukuran metode geolistrik dilakukan dengan membentangkan elektroda serta menginjeksi arus melalui dua elektroda dan beda potensial yang muncul dapat terukur sehingga didapat harga resistivitas semu yang diperoleh dari alat geolistrik. Kemudian data diolah  menggunakanRes2Div untuk mendapatkan penampang kontur 2D dari nilai resistivitas lapisan batuan. Hasil penelitian menunjukkan bahwa kontur penyebaran fluida menggunakan metode geomagnet dan geolistrik tersebar secara vertikal, penampang anomali dengan metode geomagnet memiliki nilai terendah 22,75 nT dan nilai tertinggi 69,92 nT, dari penampang anomali didapat nilai suseptibilitas 0,00054, 0,0006, 0,0016 dimana model lapisan struktur bawah permukaan terdiri dari batuan pasir, lempung dan gamping. Untuk metode geolistrik memiliki nilai resistivitas (0,00-100)  dan model lapisan batuan lempung. Nilai resistivitas (150-200)  model lapisan batuan lanau. Nilai restivitas (350 – 500)  model lapisan pasir,  dan nilai restivitas >2250  model lapisan batu gamping.   Kata kunci: Geomagnet, Geolistrik, GPS, Suseptabilitas, Resistivity, Geothermal
Pengujian Sifat Mekanik Komposit Polypropilena (Pp) Daur Ulang Dengan Filler Serat Tanaman Lidah Mertua (Sansevieras Trifasciata)
Authors: Gaol Lisbet Lumban , Motlan Motlan
Published: January 2019

Telah di lakukan penelitian pengujian sifat mekanik komposit yang menggunakan matriks polypropilena dengan filler serat tanaman lidah mertua (Sansevieras Trifasciata) yang bertujuan untuk membuat komposit polipropilena daur ulang dengan menggunakan serat tanaman lidah mertua serta mengetahui sifat mekanik uji tarik dan uji lentur dari komposit tersebut. Pada penelitian sebelumnya telah dilakukan penelitian tentang “ Sifat mekanik Komposit Polipropilena Daur Ulang Dengan Filler Serat Pandan Duri” (Ramotan, 2011). Dengan memvariasikan massa serat diperoleh nilai kekuatan tarik terbesar adalah komposit pada perbandingan fraksi massa (12,5:87,5)%, dengan tegangan maksimum  rata rata 9,63 MPa, komposit yang memiliki kekuatan lentur terbesar adalah papan komposit tanpa serat dengan kekuatan lentur maksimum rata-rata 0,53 MPa. Kekuatan lentur yang lebih baik adalah pada perbandingan (2.5:92,5)% dengan kekuatan lentur maksimum  rata-rata (UFSmaks) sebesar 0,43 MPa, perbandingan massa (7,5: 92,5)% memiliki kuat tarik dan lentur yang rendah. Maka saya tertarik untuk melakukan penelitian yang menggunakan matriks PP dengan filler tanaman lidah mertua. Dari hasil pengujian tarik diperoleh nilai terbesar (σmaks) pada komposit polypropilena dengan serat daun lidah mertua sebesar 26,61MPa yang terdapat pada perbandingan (20:80)% sedangkan nilai terendah (σmin) sebesar 14,54Mpa yang terdapat pada perbandingan (40:60)%. Dari hasil pengujian lentur diperoleh nilai terbesar ( ) pada komposit polypropilena dengan serat daun lidah mertua sebesar MPa yaitu pada perbandingan (0:100)% sedangkan nilai terendah ( ) pada komposit polypropilena dengan serat daun lidah mertua sebesar MPa yaitu terdapat pada perbandingan (60:40)%. Pencampuran yang baik antara matriks dengan filler yang digunakan sangat mempengaruhi nilai kekuatan tarik dan nilai kekuatan lentur. Kata Kunci : Sifat Mekanik, Polypropilena (Pp), Tanaman Lidah Mertua (Sansevieras Trifasciata)
Preliminary Study on Small Long-Life PWR Reactor Design Fueled Thorium with Protactinium as Burnable Poiso
Authors: Jubaidah Jubaidah
Published: January 2019

Thorium as fissile material has overweigh advantages compared to Uranium in order to have a long-life PWR reactor without replacement fuel. Additional of Protactinium as a burnable poison is effective to reduce excess reactivity in the beginning of the reactor operation. This study aims to analyze the neutronic, burnup fuel, thermal-hydraulic and kinetic calculations in regard to reactor safety. The calculation is performed with SRAC program using JENDL-32 as data library. The results show that the value of keff for 33 years are still in the range 1.0154 <keff<1.0171 and the burn-up level has increased, due to the additional fissile material as  conversion results of Th232 and Pa231. Axial linear power distribution indicates normal distribution pattern. The coolant temperature distribution in the axial direction is quite flat. Key words: PWR, Th-232, U-233, Pa-231, neutronic, thermal-hydraulic, burn-up level, reactor kinetics
KAJIAN TEORETIK UNTUK MENENTUKAN INDEKS BIAS DARI SEMIKONDUKTOR COPPER-PHTHALOCYANINE BERDASARKAN CELAH ENERGINYA
Authors: Siregar Alkhafi Maas , S Novi Febrina
Published: January 2019

Penelitian ini dilakukan untuk menentukan indeks bias semikonduktor Cu-Phthalocyanine berdasarkan celah energinya. Penentuan indeks bias menggunakan metode semi empiris ZINDO/I dan perhitungan menggunakan pemrograman matlab. Pemodelan struktur diperoleh dengan memberikan masukan, yaitu unsur, senyawa, dan jumlah atom. Optimasi dilakukan menggunakan energi HOMO dan LUMO untuk memperoleh celah energi. Dengan menggunakan Persamaan Moss, Ravindra et al, Herve-Vandamme, Reddy, dan Kumar- Singh, nilai celah energi dapat menentukan nilai indeks bias. Pada energi 3,854757 eV  untuk HOMO dan 3,538368 eV untuk LUMO, diperoleh celah energi 0,3164eV. Untuk menentukan nilai indeks bias, celah energi digunakan pada persamaan yang sesuai dengan ketentuan.  Berdasarkan ketentuan dari setiap persamaan, nilai indeks bias yang sesuai pada celah energi 0,3164 eV adalah indeks bias dari persamaan Moss, dengan nilai indeks bias yaitu 4,1627.  Kata kunci : semikonduktor, phthalocyanine, celah energi, indeks bias