bluuebunny/crossref_metadata_2025 huggingface dataset:
The Effect of the Type of Gelling Agent on the Speed of Gelation of Sol-Gels
Authors: Majerová Jana , Sklenářová Dorothea , Nevřivová Lenka
Published: October 2023

This article deals with the selection of a suitable gelling agent for refractory castable with a sol-gel binder system. The goal is to find the optimal ratio between gelation time, content, and concentration of the solution. Various salts (NaCl, NH4Cl, Ca(NO3)2) are investigated as gelling agents. Gelation curves are constructed from gelation time observations. For the design of the formula of refractory castable with a sol-gel bond, it is important to know the behavior of the sol after mixing with the gelling agent. This is the goal of the experiment. In the end, we will obtain initial data for further proposals for the composition of refractory castable with a sol-gel bond.
Cuff leak tests: analysis of diagnostic accuracy in observational cohorts of patients with acute respiratory failure
Authors: Guerra Diana , Mulkey Zachary , Nugent Kenneth
Published: October 2023

Cuff leak tests provide clinicians with information about upper airway narrowing and may help predict weaning success. However, most clinical trials reporting this measurement are small, and the utility of this test remains uncertain. We identified all clinical studies using cuff leak tests in the PubMed, Google Scholar, EMBASE, and Cochrane Central Register of Controlled Trials databases using multiple search terms, including cuff leak test, laryngeal edema, extubation, and stridor, and abstracted quantitative information on cuff leaks and outcomes (stridor and reintubation). We reviewed six studies which included 958 patients with acute respiratory failure in intensive care units. Eighty-two patients (8.5%) had postextubation stridor. The weighted mean cuff leak was 119 (±51) mls in the patients with stridor and 313 (±24) mls in patients without stridor (P<0.01). Sixty-six patients required reintubation. The presence of stridor had a sensitivity of 0.60 (95% CI 0.48-0.72), a specificity of 0.96 (95% CI 0.94-0.97), and a positive likelihood ratio of 13.4 (95% CI 6.9-25.7) for predicting reintubation. No single clinical parameter consistently predicted stridor. Patients with postextubation stridor have smaller cuff leak volumes than patients who do not have stridor and are more likely to require reintubation. Cuff leak measurements can improve decision making with extubation protocols.
Clinical and microbiological characteristics of communityacquired methicillin-resistant Staphylococcus aureus pneumonia
Authors: Martin Eric , Colmer-Hamood Jane , Frandah Wesam , Raj Rishi , Nugent Kenneth
Published: October 2023

Methicillin-resistant Staphylococcus aureus (MRSA) infections now occur in healthy adults in community settings. We searched the PubMed database to identify relevant articles on the clinical presentation, epidemiology, virulence, and treatment of community-acquired MRSA (CA-MRSA) infections, including pneumonia. This information was summarized in a narrative review.MRSA infections cause approximately 30 infections per 100,000 people per year in the USA, and twenty percent of these infections are secondary to CA-MRSA. These community-acquired infections often involve the skin and subcutaneous tissue but can also involve visceral tissues such as the lung and bone. The overall mortality in patients with invasive disease is approximately 10%; it approaches 50% in patients with pneumonia. The bacterial isolates from these infections have the staphylococcal chromosome cassette mec types 4 and 5. This genetic characteristic produces beta-lactam resistance and helps distinguish these isolates from hospital- acquired MRSA, which usually have mec types 1-3. Some CA-MRSA isolates release the Panton-Valentine leukocidin (PVL), which causes neutropenia and tissue necrosis; other toxins also contribute to the virulence of these infections. Empiric therapy should include vancomycin or linezolid. CA-MRSA infections can have fulminant courses and high mortality rates. Physicians should consider these infections as possible emergencies with a high risk for organ system failure and shock.
A case of Churg-Strauss syndrome complicated with bilateral central retinal artery occlusion
Authors: Uchibori Ken , Shinohara Emi , Furusawa Haruhiko , Tominaga Shinichiro , Natsume Ichiro , Ohkouchi Minoru
Published: October 2023

A 56-year-old Japanese woman treated for bronchial asthma came to our hospital because of sudden vision loss of the left eye and plantar numbness of the right foot. Central retinal artery occlusion (CRAO) was diagnosed. Vision loss of the right eye also appeared, and the numbness of the right foot worsened. She was diagnosed with Churg-Strauss syndrome (CSS) due to bronchial asthma, eosinophilia, and vasculitis (CRAO and numbness). Her symptoms were unresponsive to systemic corticosteroid therapy, but improved when cyclophosphamide pulse was added. Vision disorders are uncommon manifestations of CSS. Close co-ordination with ophthalmologists is important for diagnosis and treatment.
La qualità di vita nelle cure palliative pediatriche: relazione di cura o relazione che cura?
Authors: Ruggiero Rossana , Zucaro Luigi , Kaczmarek Stefano
Published: October 2023

La medicina contemporanea finisce per relegare a minus ciò che non è in grado di combattere la causa della malattia. L’esperienza delle cure palliative pediatriche si contrappone a questo, mettendo al centro della medicina il prendersi cura. Gli autori delineano un percorso etico che porta ad un nuovo concetto di qualità di vita, a partire da virtù e valori etici: pallio, compassione, speranza e tempo. Laddove l’inguaribilità schiude le porte al curare pur senza guarire, la dimensione umana della persona nelle relazioni ritrova la sua collocazione preminente. Il pallio rappresenta la volontà di porre al centro il malato, la vita relazionale nella sua globalità garantendone il rispetto della sua dignità; il pallium copre la sua nuda condizione di sofferenza nella fase ultima della vita. La compassione diventa “sentire” l’altro riconoscendolo nel luogo del suo dolore, anche nelle situazioni in cui la relazione è necessario superi i limiti del “verbale”. La categoria della speranza è più chiara, preservando dal rischio di delusioni che nascono da una cultura che attribuisce alla medicina una illusoria onnipotenza. Nessun rischio di sconfinare in un abbandono terapeutico, piuttosto si apre una nuova prospettiva del tempo della vita: non più una inesorabile sottrazione di vita (chronòs), ma l’occasione propizia di valorizzare il tempo della vita attraverso la relazione (kairòs). Gli autori ridefiniscono il criterio qualità di vita in qualità delle relazioni della vita opposta all’individualismo e alla conseguente solitudine del malato, che orienta le scelte terapeutiche verso una cura olistica della persona e non solo della malattia.
Parsonage-Turner Syndrome following COVID-19 Infection
Authors: Ansari Behnaz , Eishi Oskouei Alireza , Moeinzadeh Firouzeh
Published: October 2023

Parsonage-Turner syndrome (PTS) is a rare syndrome of unknown etiology; however, it is believed that an abnormality of immune response after a previous infection may be the cause of the disease. We report neuralgic amyotrophy in a patient with a history of kidney transplantation with severe acute respiratory distress syndrome coronavirus 2 infection. This literature is reviewed regarding clinical presentation, etiology, treatment, and prognosis of PTS after COVID-19 infection. We should consider PTS as another complication of COVID-19 infection.
Study of the Apoptotic Impacts of Hazelnut Oil on the Colorectal Cancer Cell Line
Authors: Ramezan Mina , Mahmoodzadeh Hosseini Hamideh , Salimi Ali , Ramezan Yousef
Published: October 2023

Background:

Hazelnut oil has a unique structure with a high oleic acid content, tocopherol, tocotrienols, and other bioactive compounds, such as phytosterols. These biochemical compounds have been widely studied because of their potential health properties. Understanding the process of apoptosis is the basis of new therapies contributing to cancer cells' death. Recently, the potential role of the evolutionary-reserved bcl-2 protein family in tumor progression and prognosis of some malignancies has been addressed in several studies. The present study is aimed at evaluating the effect of apoptotic properties of hazelnut oil on colorectal cancer cells through the major members of this family (bax and bcl-2).

Materials and Methods:

MTT assay, apoptotic cell staining (using Annexin V and propidium iodide), flow cytometry, and real-time PCR were used to evaluate the toxicity, percentage of apoptotic cells, and bax and bcl-2 genes' expression after exposing HT29 cells to hazelnut oil.

Results:

After hazelnut treatment, significant decreases in cell viability, and the gene expression of bax and bcl-2 were observed compared to the control group (P < 0.05). In addition, the total percentage of apoptotic cells after hazelnut oil treatment showed a significant increase in comparison with the negative control group (P < 0.05).

Conclusion:

Hazelnut oil appears to cause the death of cancerous cells through an apoptotic mechanism.
Comparative Study of the Effect of Two Different Doses of Dexmedetomidine to Prevent Emergence Agitation in Tonsillectomy in Children Aged 2 to 12 Years Old
Authors: Shahhosseini Sedighe , Naderi Boldaji Hossein , Shetabi Hamidreza , Shafa Amir
Published: October 2023

Background:

Emergence agitation (EA) is one of the complications following anesthesia in pediatric surgery. Various drugs are used to prevent this complication, and one of them is dexmedetomidine. Choosing the right dose of this drug for the best efficiency is an important issue due to this complication. The main purpose of this study is to evaluate the prophylactic effect of intravenous dexmedetomidine in different doses in preventing EA after tonsillectomy in children.

Materials and Methods:

Our study was a double-blind clinical trial performed on 75 children ASAI, II candidates for tonsillectomy. Patients were divided into three groups. The group 1 received a dose of 0.6 μg/kg per hour and group 2 received a dose of 0.3 μg/kg per hour and group 3 was the control group. Then vital signs and observational pain score (OPS) and pediatric anesthesia emergence delirium (PAEDS) criteria were measured in patients. The collected data were analyzed by using SPSS software version 23 and non-parametric tests such as Friedman, Mann-Whitney.

Results:

According to the data analysis, mean blood pressure, mean heart rate, OPS and PAEDS score in group 1 were lower than other groups. Also, the average time of staying in recovery and extubation in group 1 was less than other groups.

Conclusion:

A dose of 0.6 μg/kg dexmedetomidine has a better effect on reducing EA (emergence agitation) after pediatric tonsillectomy.
Posterior Leaflet of Mitral Valve—Is it Really Tri-scalloped? —A Morphological and Morphometric Study in North Indian Cadaveric Hearts
Authors: Shree Bhagya , Singla Rajan Kumar , Soni Sachin , Kumar Ashwini , Sharma Sanjay Kumar , Das Sushant Swaroop , Puri Nidhi
Published: October 2023

Background:

Maintaining normal left ventricular geometry and function depends on the mitral valve's normal integrity. Irreparable damage to the mitral valve calls for its replacement using either a valve made up of biological tissue or metal, pyrolytic carbon, and similar materials.

Materials and Methods:

The material consists of 50 formalin-fixed adults, seemingly normal cadaveric hearts of either sex which were received from the Department of Anatomy of various institutes in the north region. These hearts were cut open to access the mitral valve in the left ventricle.

Results:

In this study, the posterior leaflet was semi-oval in shape being 3.72 cm wide at the base. Usually said to be tri-scalloped, interestingly, it was found so only in 56% of the hearts; being bi-scalloped in 20% and single-cusped in 16% of the hearts. Even four scallops and six scallops were observed in three (6%) and one (2%) hearts, respectively.

Conclusions:

To conclude, notable variation has been seen in the scallops of posterolateral cusps in the present study. The number of scallops varies greatly as single, double, three, four, or tetra-scalloped and most significant six or hexa-scalloped which has never been reported in the previous studies. To understand the rationale behind each unique architectural layout, such noticeable variations are crucial for scientists around the world. Cardiothoracic surgeons could find this information valuable for mitral valve surgery repair.
Vanishing first cohomology and strong 1-boundedness for von Neumann algebras
Authors: Hayes Ben , Jekel David , Kunnawalkam Elayavalli Srivatsav
Published: October 2023

We obtain a new proof of Shlyakhtenko's result which
states that if

G

is a sofic, finitely presented group with
vanishing first

\ell^2

-Betti number, then

L(G)

is strongly
1-bounded. Our proof of this result adapts and simplifies Jung's
technical arguments which showed strong 1-boundedness under
certain conditions on the Fuglede–Kadison determinant of the
matrix capturing the relations. Our proof also features a key
idea due to Jung which involves an iterative estimate for the
covering numbers of microstate spaces. We also use the works of
Shlyakhtenko and Shalom to give a short proof that the von
Neumann algebras of sofic groups with Property (T) are
strongly 1 bounded, which is a special case of another result by
the authors.
Believe it or not. The role of ideology as a predictor of trust in mainstream and social media during COVID-19
Authors: Cordero Guillermo , Alonso-Muñoz Laura , Casero-Ripollés Andreu
Published: October 2023

Introduction: The goal of this article is to analyze the extent to which ideology intervenes in citizens' trust in the news that appears in traditional and social media during COVID-19. Methodology: To do this, a quantitative approach based on the online survey technique is used. The questionnaire was launched in July 2021 through the Qualtrics platform and was answered by 2,803 citizens residing in Brazil (726), Spain (682), the United States (694), and India (702). Results: We found a connection between ideology and confidence in traditional media, strongly conditioned by the socio-political context. In addition, right-wing citizens tend to trust the information they receive from digital platforms such as Twitter, Facebook, Instagram, or WhatsApp better than left-wing citizens. This uneven impact of trust in the media could result in a heterogeneous effect of fake news, with right-wing citizens most likely believing political news appearing on social media Discussion and Conclusions: This article contributes to expanding prior knowledge about the trust in mainstream and social media, with considerable emphasis on the factors that have a predominant influence in four countries with different social and political structures and media systems: Spain, United States, India, and Brazil. In this context, it has been observed how ideology is an essential factor in all of them. When this relevant variable is controlled for, and despite what previous studies had determined (Newman et al., 2021), factors such as educational or income level do not seem to play a significant role.
Towards an Integrated Approach to Solid Waste Management in Ghanaian Cities
Authors: Sheburah Essien Rosina , Adjei Moses , Owusu Victor
Published: October 2023

Solid Waste Management (SWM) in cities has become a theme of utmost importance in urban geographycompared to studies in rural areas which have smaller population sizes and limited consumption optionsthat are relatively more manageable. Existing studies reveal that integration of formal and informal SWMactors is the needed mechanism to overcome SWM challenges. Integration is also at the heart of the 2012Ghana National Urban Policy, yet urban spaces are zoned under public-private partnership (PPP)arrangement with private formal SWM actors. How to integrate the burgeoning numbers of privateinformal SWM service providers still remains unaddressed owing to a host of disparate institutional,political, and socio-economic factors. Using field-based data collected in three open-air markets in Accra,this paper examines the integration pathways used to include informal SWM actors in the context of PPPand thence argues for the need to rethink current SWM approaches in a participatory manner since mostGhanaian cities are facing limited financial and infrastructural resources, growing inequalities andincreasing informality regarding urban metabolism flow.
Activity-based investigation of the possible anti-diabetic potentials of some Nigerian medicinal plants
Authors: Eluehike N. , Agu K. C. , Ikponmwosa-Eweka O. , Eromosele A.I. , Olufakunye J.
Published: October 2023

A major therapeutic approach presently used in managing Type 2 Diabetes mellitus is the use of a-glucosidase and a -amylase inhibitors. Hence the growing attention in the quest for medicinal plants of natural sources with inhibitory potentials on these enzymes. This study was done, therefore, to determine the inhibitory potentials of the different parts of three medicinal plants; Nigella sativum (seeds), Spondias mombin (leaves and stem bark), and Picralima nitida (seeds and mesocarp) on a-amylase and a- glucosidase as well as to determine inhibition kinetics. The in vitro a-amylase and a-glucosidase inhibitory activities of the plant extract were assessed using 3,5-dinitrosalicylic acid (DNS) and p-nitro-phenyl-a-D glucopyranoside (p-NPG) respectively. The results indicated that all plant extracts assayed exhibited better a- glucosidase inhibitory effects than the reference drug(acarbose), as indicated by the higher IC50 (76.10 μg/mL) value of the reference drug, whereas the n-hexane extract of N. sativum seeds gave the best a-amylase effect (IC50 = 35.83 μg/mL). All the extracts exhibited an “uncompetitive” type of inhibition pattern. Our findings hence support the use of these plants in the management of diabetic conditions.
Morphological characterization of selected cowpea [Vigna unguiculata (L.) Walp.] accessions from International Institute of Tropical Agriculture, Ibadan, Nigeria
Authors: Onuminya T.O. , Ogunkanmi M.A. , Ogunkanmi L.A.
Published: October 2023

Characterization of available germplasm is a necessary step to facilitate breeding programs worldwide. Therefore, this study aimed to characterize twenty accessions of Cowpea from the International Institute of Tropical Agriculture, Nigeria. The accessions were planted in a randomized complete block design with three replicates. The morphological characters of seedlings were assessed following the International Board for Plant Genetic Resource cowpea descriptor list (IBPGR) and twenty-nine descriptors were used. Eighteen accessions showed semi-erect habits while two showed erect plant growth habits. The number of Days to first flowering among the selected accessions was 35-45 while the number of days to first pod was 37-47. Peduncle length was observed to be 12-35 cm, Pod length was 10.61-22.81 cm while seed length was 6.10-9.93 cm among sampled accessions. Morphological assessment of the accessions showed a dendogram of three clusters with six (A), nine (B) and four (C) accessions respectively. One accession TVu-12501 formed an outgroup owing to the uniqueness of its terminal petiole length. The cluster analysis substantiated the existence of diversity among the twenty accessions for the morphological traits studied and posits TVu-12501 accession as a morphologically superior accession to be studied further for selection in breeding programmes in the West African region.
КОСАРА ТЕОДОРИТА ОД ИСТОРИЈЕ ДО КУЛТА
Authors: Ђекић Ђорђе
Published: October 2023

Пред читаоцем је још једна научно-монографска студија про-фесора Ђорђа Ђекића која се односи на наш рани средњи век. По свом жанру ова студија спада најпре у врсту истраживачких радова који се могу именовати као посопографија – студија о знаменитим историјски личностима, каква је несумњиво била кнегиња Косара Теодорита, супруга Светог кнеза Владимира (+1016). Исто тако, ова студија се може по свом садржају сврстати и у агиографију – студи-ју које се баве проучавањем Светитеља и њиховог живота и подвига у складу са древним предањем Цркве све до најновијих времена. Житија светих спадају у најстарије писано наслеђе Цркве и чине неотуђиви саставни део светитељског поштовања и култа Светите-ља, поред Службе – богослужбеног поштовања, и иконогафије – ликовно представљање Светих на иконама, фрескама, у катакомбама или штампаним делима. Научна студија која је пред нама резултат је вишегодишњег пажљивог и свестраног проучавања веома сложене црквеноисториј-ске проблематике везане за лично и дела брачног пара Светога кнеза Владимира и његове супруге Преподобне Косаре Теодорите. Аутор у својој мултидисциплинарној – црквеноисторијској и агиографској анализи полази од наранијих писаних извора – Житија ових Свети-теља. Консултује и друге савремене изворе и усмена предања која су касније записивана као плод усменог, неписаног предања које је живело у нашем народу као израз светитељског поштовања и култа који је веома рано заживео на нашим ширим просторима. Ти извори су често контроверзни и није лако донети тачне закључке у научно-истраживачком смислу речи.
Technical and legal regulation of urban railways
Authors: Romanov A. V. , Kiselev A. A.
Published: October 2023

The article deals with the issues of legal and technical regulation of railway transport infrastructure facilities in cities and urban agglomerations. An attempt was made to determine the legal status of such objects.

The features of such railways are considered, the need for highlighting regulation of urban railways is indicated. It is proposed to initiate work on establishing the priority of passenger transportation over freight in the territory of cities and urban agglomerations.

Possible ways to solve the stated problem are proposed, consisting in several measures, including the deﬁnition of a list of regulatory documents that prevent the allocation of a separate regulation of railway transport in cities and urban agglomerations, conducting relevant scientiﬁc research and preparing proposals for amending regulatory documents.
Identification of Hazards and Assessment of Occupational Safety and Health (K3) Risk in Projects Runway and Taxiway Lolak Bolaang Mongondow Airport Uses The Methodhirarc (Hazard Identification and Risk Assessment Risk Control)
Authors: Lalenoh Djoni Hermanus , Torry Dundu Arestides K. , Lefrandt Lucia. I. R. , Egbert Rumayar Audie Lexie , Malingkas Grace Yoyce
Published: October 2023

The Lolak Bolaang Mongondow Airport Runway and Taxiway Project represents one of the emerging airport developments characterized by a heightened susceptibility to accidents. Occupational Safety and Health (K3), an integral component of multifaceted initiatives aimed at mitigating workplace accidents while augmenting labor productivity and efficiency, has been effectively integrated into this undertaking. Among the methodologies employed for its implementation, the Hazard Identification and Risk Assessment Risk Control (HIRARC) approach takes precedence. The primary objective of this research is to meticulously identify hazards, conduct a comprehensive analysis of workplace safety risks, and institute measures to curtail these risks within the scope of the Lolak Bolaang Mongondow Airport Runway and Taxiway project. This endeavor seeks to curtail, and ideally eliminate, workplace accidents. Data acquisition was facilitated through a combination of observational techniques and structured interviews with service providers and construction contractors, involving 63 respondents. To ascertain the categorization of risk levels, spanning from low to high, a meticulous workplace safety risk analysis was executed. The outcome of this analysis, encompassing a total of 69 sub-items of work, reveals that the highest risk level is attributed to runway construction work, accounting for 53% of the identified risks (9 out of 17). The second-highest risk category pertains to PKP-PK work, constituting 40% of the 40 identified risks, and the third-highest risk level is linked to operational road pavement construction, with a risk percentage of 31%. Subsequent to the identification and assessment of risks, risk control measures are diligently executed. This phase signifies the culmination of data processing within the framework of the HIRARC methodology.
Implementación de un agente inteligente para la identificación, recolección y entrega bajo condiciones variables de posición en una matriz cambiante
Authors: Dueñas Carlos Reyes , Gutiérrez Mariela Yanin Magaña
Published: October 2023

Se presenta un agente inteligente a través de una aplicación desarrollada para identificar la posición de un objetivo dentro de una matriz, para posteriormente ir a recolectar el objeto ubicado en esa posición, mismo que será llevado por el agente a otra posición destino. La matriz es un escenario cambiante. Los objetos para recolectar pueden ser posicionados aleatoriamente en cualquier lugar dentro de la matriz. Los objetivos destino pueden ubicarse en cualquier punto aleatorio, y cambiar cada cierto tiempo aleatoriamente, obligando al agente a tomar la decisión de una nueva ruta para llegar a él. El agente puede valorar varios objetos a recolectar, y diversos agentes a la vez, mismos que deberán recolectar cada uno un objeto, para finalmente perseguir el destino de acuerdo con el agente que se encuentre más cercano al objetivo destino. El agente inteligente demuestra que puede ser aplicado a sistemas de recolección y entrega.
Factors Associated with Decompression and Strabismus Surgery in Thyroid Eye Disease
Authors: Looi ALG , Luu CD , Wong TY , Seah LL , Rootman J
Published: October 2023

Introduction: Prognostication of the thyroid patient with eye disease aids in the choice of treatment strategy. To facilitate this, we investigated factors associated with decompression and/ or strabismus surgery in the Singaporean population. Materials and Methods: A 5-year retrospective study was performed. Patients who required strabismus and/or decompression surgery (n = 23) were compared to those who did not undergo either surgery (n = 44). Individual and multivariate age-adjusted odds ratios were calculated to determine significant associations. Results: Individually, male gender [odds ratio (OR), 4.5; 95% confidence interval (CI), 1.5 to 13.4], uncontrolled hyperthyroidism (OR, 4.0; 95% CI, 1.1 to 14.3), steroid therapy (OR, 7.4; 95% CI, 2.3 to 24), diplopia (OR, 7.3; 95% CI, 2.3 to 23.1), objective vertical myopathy (OR, 11.7; 95% CI, 1.4 to 96.0), elevated intraocular pressure in the primary position (OR, 3.4; 95% CI, 1.2 to 10.0) and clinical evidence of optic neuropathy (OR, 13.1; 95% CI, 1.4 to 124.6) were significantly associated with the need for surgery. Logistic regression analysis showed the greater impact of male gender (OR, 4.2; 95% CI, 1.2 to 15.4), optic neuropathy (OR, 13.0; 95% CI, 1.2 to 143.7) and previous steroid therapy (OR, 4.2; 95%CI, 1.1 to 16.2) on prognostication. Conclusions: Chances of requiring strabismus and/or decompression surgery are significantly higher for male patients and those with uncontrolled hyperthyroidism. In particular, male patients with optic neuropathy and a history of previous steroid therapy warrant a graver prognosis.
Use of Physical Restraints in Nursing Homes: Current Practice in Singapore
Authors: Mamun K , Lim J
Published: October 2023

Introduction: One of the indicators of quality care in nursing homes is the proper use of physical restraints. Restraints have been associated with multiple complications, such as pressure ulcers, incontinence and immobility. The aim of our study was to assess the indication, use and complications related to physical restraints in Singapore nursing homes. Materials and Methods: All residents aged >65 years old from 3 nursing homes were included in the study. A geriatrician reviewed the medical records of all elderly residents on restraints. Nursing staff interviews were also done to assess their knowledge regarding restraint use. A brief medical record review was also done for the elderly residents without restraints. Results: Out of 390 elderly residents, 91 were on physical restraints. The mean age of these residents were 80.1 years; 67% were female, 90.1% were Chinese and 82.4% belonged to functional category IV. Both urinary and faecal incontinence were observed in 97.8% of residents. Forty-six (50.5%) residents had no documented indication for restraints. It was noted that 20 (22%) residents were restrained to prevent dislodgement of the feeding tube, 17 (18.7%) were restrained to prevent falls and 8 (8.8%) were restrained for agitation. There were documented trials of removal of restraints for only 21 (23.1%) residents. Alternative approaches, such as diversion technique, were used for 31 (34.1%) residents to avoid restraint use. Conclusion: Our study revealed a high rate of restraint use in the nursing homes. A restraint protocol should be available in every nursing home, requiring physician approval for the long-term application of physical restraints and intermittent reviews by physicians to assess the continued need for restraints.
Development of Ipsilateral Adrenocortical Carcinoma Sixteen Years after Resection of an Adrenal Tumour Causing Cushing’s Syndrome
Authors: Tan HS , Thai AC , Nga ME , Mukherjee JJ
Published: October 2023

Introduction: At times, it may be difficult to differentiate early stage, low-grade adrenocortical carcinoma from benign adrenal adenoma. Clinical Picture: A 53-year-old lady underwent right adrenalectomy for a 4-cm adrenocortical tumour causing Cushing’s syndrome. Histology revealed an adrenocortical adenoma. Sixteen years later, she presented with a 14-cm adrenal tumour, again on the right side. Treatment: She underwent surgical removal of the tumour. Histology confirmed adrenocortical carcinoma. Outcome: She died of metastatic disease 17 months later. Conclusions: This case highlights the importance of long-term, systematic follow-up of patients treated for benign adrenal adenomas, especially if the tumour size exceeds 4 cm.
POTENTIAL USE OF AN EDIBLE CANDELILLA WAX-BASED COATING TO EXTEND THE SHELF LIFE OF PASSION FRUIT
Authors: Sánchez-Loredo Eliseo , Martínez-Pérez Alaín , Muñiz-Márquez Diana Beatriz , Rojas Romeo , Wong-Paz Jorge Enrique
Published: October 2023

Passion fruit (Passiflora edulis f. flavicarpa Degener) is not widely traded due to its short shelf life. Edible coatings can be used to extend the postharvest life of fruits. The objective of this study was to develop a candelilla wax-based coating (Euphorbia antisyphilitica Zucc) for the preservation of passion fruit. Three coating formulations (C1, C2, and C3) were made with pectin, glycerol, and candelilla wax and applied by immersion. Weight loss and changes in physical appearance were used to assess shelf life under two storage conditions: room temperature (32 °C/6 days) and refrigeration (6.6 °C/32 days). Uncoated fruit in both storage conditions served as controls. Furthermore, a physicochemical characterization of the coatings was performed. Coated fruit at room temperature showed an improvement in weight retention compared to controls, but no differences in physical appearance were observed. In fruits stored under refrigeration, only C2 had less weight loss compared to the control, while C3 maintained a better physical appearance. In terms of coating characterization, C3 presented the lowest moisture content and thickness. C1 obtained the highest density value, while C1 also had the highest water vapor permeability rate (TPVA) value. The application of the C2 coating was effective in preserving the fruit for a longer period of time, and this coating has the lowest TPVA value, which is related to the decrease in weight loss in the fruit.
Familial case of inherited human herpesvirus 6A with phylogenetic assessment
Authors: Goleva OV , Danilov LG , Kusakin AV , Eismont YuA , Babachenko IV , Tian NS , Chukhlovin AB , Krylov AV , Glotov OS
Published: October 2023

The paper reports a familial case of HHV-6A chromosomal integration being an important and relevant issue of genetics and medicine. The study was aimed to test the hypothesis of HHV-6A chromosomal integration and vertical transmission in patient with persistent virus detection during recurrent respiratory diseases and the asymptomatic period when there were no health complaints. Sequencing of the patient’s father genome DNA was performed, and a phylogenetic tree was constructed by aligning 270 HHV-6A/B genome assemblies from the GenBank database. As a result, a familial case of ciHHV-6A transmission was identified. It was found that the detected ciHHV-6A observed on the phylogenetic tree was closely related to other two chromosomally integrated HHV-6A sequences reported by Moscow researchers. The study confirmed HHV-6A chromosomal integration. Further precise chromosome mapping of ciHHV-6A would be useful in terms of excluding probable somatic disorders associated with the chromosome structure alteration following HHV-6, particularly HHV-6A, integration, as well as for identification of insertion sites specific for various geographic locations.
Sustainability Metrics and Green Finance for Chemicals
Authors: Ferrari Annalisa , Buscemi Antonino
Published: October 2023

Abstract

In this article we investigate the aspects that link sustainable finance and sustainable chemistry on the basis of the theoretical definitions currently available. Our aim is to analyse what reflections have been made by scholars and to identify a further effort to understand the dynamics underlying these two fundamental sectors within the transition process of the global economy. In section 1 we analyse the relationship between sustainability and economic development, in section 2 we define the boundary of the role of sustainable finance, in section 3 we address the discussion and in section 4 we present our conclusions.

JEL classification numbers: G00, G2, M14, O44, Q56.
Keywords: Sustainable finance, Metrics, Environmental Responsibility, sustainability, Corporate social performance and strategy, Chemicals.
kay Gecko (Gekko gecko) in Bali Province, Indonesia
Authors: Cahyani Ni Kadek Dita , Widiastuti Kadek Andina , Fauzan Muhammad Fakhri , Zakky Quraisy , Hibban Hartono Ibnu , Ramadhan Dimas Bayu Nur , Riyanto Awal , Hamidy Amir
Published: October 2023

The tokay gecko (Gekko gecko) is known to be one of the species that plays an important role in the ecosystem, especially in controlling pest populations (locusts, mosquitoes, crickets and moths). Tokay geckos also have a high need for medical care purposes and pets. verexploitation and territorial conversion affect tokay gecko populations. this research to conduct a survey and extrapolation of the gecko population in Bali province. The survey was done through a visual survey of dating with three different methods; face-to-face video interview and meeting (IDVE), direct eye contact (DVE) and habitat survey (HS). The survey was conducted in nine districts in Bali from December 2021 to January 2022 with a total of 20 survey points. The total sample area for this study is 56.84 hectare (ha) with 842 individuals of tokay geckos were recorded during the survey. Out of a total of 578,006 hectares area of ​​the province of Bali, about 54% of the total area is a potential area for tokay gecko habitat. The estimated number of tokay geckos in Bali province from this study is 4 million individuals. Result habitat preferences of tokay geckos in Bali province in this study are valuable baseline data for policy producer in determining tokay gecko catch quota.
Studi Etnobotani dalam Makanan Tradisional Nasi Liwet, Hidangan Khas Sunda di Kecamatan Mustikajaya, Bekasi
Authors: Simanullang Liana Seftiyani
Published: October 2023

Traditional food is food consumed by a particular community, reflecting the local potential and wisdom, as well as a distinctive flavor accepted by that community. Typically, traditional food is characterized by the characteristics of a region, the values within that region, the manifestation of regional culture, specificity, and the natural potential of each area. Mustikajaya District, Bekasi City, is still predominantly inhabited by the Sundanese people, followed by the Javanese, Malay, and Batak ethnic groups. Consequently, there are still many traditional Sundanese foods distributed and sold in the Mustikajaya District, one of which is Nasi Liwet, a traditional Sundanese dish. Ethnobotanical studies on the traditional Sundanese food, Nasi Liwet, have not been conducted, especially in the Mustikajaya District, Bekasi. This research aims to provide information on the biodiversity used as spices and complementary ingredients. It then connects these ethnobotanical studies with the processing and cultural presentation of Nasi Liwet, as well as the philosophy and historical value of this traditional Sundanese dish.
Uji Ketahanan Pewarna Alami Kain Tenun Ikat Kecamatan Noemuti Timur Pada Preparat Basah Jaringan Tumbuhan
Authors: Bria Graciana Gabriela , Seran Yoseph Nahak , Naisumu Yolanda Getrudis
Published: October 2023

This study aims to determine the resistance of natural dyes and to determine the length of time of resistance of natural dyes of ikat woven fabrics in wet preparations of plant tissues. This study used the method of description and direct experiment. The design used a complete random design (RAL) with 2 treatment factors, namely plant dye and length of coloring time. Coloring plants are turmeric (Curcuma longa L) and mahogany (Swietenia mahagoni (L) Jack.,, and the length of coloring time is 0 minutes, 60 minutes, 120 minutes, and 180 minutes. Data analysis in this study is descriptive qualitative and descriptive quantitative. The results showed that the natural dye of ikat woven cloth in East Noemuti District consisted of yellow color extracted from turmeric rhizomes (Curcuma longa L), maroon color extracted from turmeric rhizomes (Curcuma longa L) added lime and detergent, red color extracted from mahogany bark (Swietenia mahagoni (L). Jack) can survive wet preparations of spinach (Amaranthus tricolor) and corn (Zea mays) plant tissues and the length of time of dye resistance to wet preparations of spinach (Amaranthus tricolor) and corn (Zea mays) plant tissues which shows the best results is 180 minutes.
Pengaruh Sari Pati Daun Telang (Clitoria ternatea) Terhadap Zona Hambat Staphylococcus aureus
Authors: Nuryani Intan , Widiya Mareta , Fitriani Linna
Published: October 2023

Staphylococcus aureus bacteria often cause infections ranging from boils, impetigo, furunculitis, vesicobullial dermatoses and cellulitis to severe skin infections in the form of Staphylococcal Scaled Skin Syndrome. Telang leaf plant (Clitoria ternatea) contains alkaloids, flavonoids, tannins, saponins which have antibacterial activity. This study aims to determine the effect of butterfly pea leaf extract (Clitoria ternatea) on the inhibition zone of Staphylococcus aureus. This type of research is a quantitative study using a completely randomized design (CRD). The results of the Kruskal-Wallis statistical test showed that it was significant, namely 0.005 ˂ 0.05, which means that the results were significant. This shows that giving a dose of butterfly pea leaf extract (Clitoria ternate) has an effect on Staphylococcus aureus. And the results of the Mann-Whitney test show that out of the 10 data groups there are 6 groups which state that there is a significant difference where the data Asymp.sig is ˂ 0.05, while the 4 data groups say there is no difference where the data is Asymp. its sig ˃ 0.05.
Quality, field germination of seeds and phenolic profiles of modern sugar sorghum hybrids
Authors: Tereshchenko I. S. , Storozhyk L. I.
Published: October 2023

Purpose. To establish and analyze the biological features of seed quality indicators, field germination of seeds, and phytochemical composition of modern sugar sorghum hybrids 'Sugargraze ARG' (Argentina), 'Sioux', 'Mohawk' (USA) and 'Ananas' (Ukraine).
Methods. Physiological-biochemical, agrochemical and statistical methods were used in the study. The content of phytochemicals in the seeds of the studied sugar sorghum hybrids was determined by the extraction method.
Results. In the studied sorghum hybrids, a high concentration of the main phenolic profiles of the seeds was established. The quantitative component depended on the color of the pericarp of the grain, which affected the quality indicators of germination and field germination of the seeds. In hybrid 'Sioux', which has a dark brown color of the pericarp and the highest content of polyphenolic profiles (50.4%), germination energy, laboratory and field seed germination were low and amounted to 84, 90 and 80%, respectively. The high level of these indicators was formed by the hybrid 'Ananas' with the lowest content of phenolic profiles (38.1%) and with non-pigmented pericarp, which had germination energy, laboratory and field similarity of 96, 98 and 89%, respectively. Hybrids 'Sugargraze ARG' (light brown grain color) and 'Mohawk' (pink grain color) had indicators of germination energy of 90 and 95%, laboratory germination 93 and 96%, field germination 82 and 81%, respectively, and were characterized by an average content of phenolics profiles of 45.7 and 42.5%, respectively.
Conclusions. The hybrid of American origin 'Sioux' that has a high content of phenolic compounds in the seeds, ensured the preservation of plants in the phase of full germination at the level of 87%, while Ukrainian hybrid 'Ananas' with the lowest content of phytochemical compounds also had the lowest preservation rate (80%) among the studied hybrids. In 'Sugargraze ARG' and 'Mohawk' that have medium phenol content, the rate of plants preserved in the full germination stage was 84–85%.
Analysis of Seawater Intrusion Based on Conductivity Method and Hydro-Chemical Approaches to Shallow Coastal Wells in Alluvial Plains of Kendal Regency, Central Java
Authors: Ferdiansyah Wisnu Prayoga , Nurwidyanto M. Irham , Widada Sugeng
Published: October 2023

Kendal Regency is one of the regencies in Central Java which has 0.64% of population growth and 1.023/km2 of population density per year. Kendal Regency is also known as Industrial Area. On other hand, Regional Drinking Water Company (PDAM) has increased in demand every year, and mostly being used for household needs. These indicates that there is less surface water supply in Kendal Regency. As a result, there are negative effects such as lowering the ground water level, decreasing the quantity and quality of ground water, and seawater intrusion. This research was made to determine the distribution of seawater intrusion in the coastal areas of Kendal Regency. The method used in this research was to find the value of Electrical Conductivity in well water. And then, the well water was tested using hydro-chemical test to determined the cause of intrusion in the research area by projecting on the Trilinear Piper diagram. This research was conducted in 7 districts in Kendal Regency which are located in 38 shallow well points in coastal area. The result shows that the values of Electrical Conductivity have range of 436 μS/cm to 5.083 μS/cm. based on these results, the well water in this research area can be classified into fresh water, fresh-brackish water, and brackish water. The analysis using Trilinear Piper diagram can be concluded that the saltiness of the well water in the research area are occurred due to seawater intrusion.
Analisis Hubungan Panjang Berat Pada Ikan Selar Kuning Selaroides leptolepis di Pangkalan Pendaratan Ikan (PPI), Kota Sorong
Authors: Yanti Dwi Indah Widya , Masengi Melisa , Penina Palemba Yolda
Published: October 2023

Sorong City is located in a strategic area in Southwest Papua Province. The development of the fisheries sector in Sorong City is increasing, and various efforts are being made by the Regional Government, one of which is to support Fish Landing Base (PPI) facilities that are needed by fishermen as a place to land their catch, which is then purchased by collectors or consumers. The types of fish that are generally landed in PPI Sorong City are generally large, medium, and small pelagic fish. Yellow trevally (Selaroides leptolepis), known locally as Oci fish, is one of the most popular fish types in Sorong. This study aimed to determine the relationship between the length and weight of yellow trevally (Selaroides leptolepis) as a basis for fisheries resource management. The research was conducted at PPI Sorong City in July, August, and September 2022. The samples used were obtained from Selar Fish landed in PPI Sorong City, which were then measured and weighed. The results obtained in July were b= 2.32, which was negative allometric; in August, b= 2.60, which was negative allometric; and in September, b= 3.10, which was positive allometric.
Improving Diabetes Condition Through Health Literacy: A Case Study From Cianjur, West Java, Indonesia
Authors: Siti Kamillah Siti Kamillah , Panduragan Santhna Letchmi , Poddar Sandeep , Bhaumik Amiya
Published: October 2023

Introduction: The global challenge in managing diabetes is the low level of patient health literacy. Health professionals have promoted the use of technology as an effort to improve patient health literacy. However, the data shows health literacy of urban area patients is higher than in rural areas. Also, many studies have focused on health literacy by using a quantitative approach and few studies have explored this issue more deeply to understand a patient’s real story about health literacy after they use the diabetes application. Method: We conducted a qualitative approach by using in-depth interviews to assess ten patients’ health literacy from one of the rural areas in Indonesia, before and after using the diabetes application. Results: The results showed that there was a change in the patients’ habit to take care of themselves more independently through the diabetes application compared to when they were more dependent on their families before they utilized the diabetes application. Conclusion: This study proved that health literacy could improve by using the diabetes application for patients in rural areas.
The Effect of Lactation Massage Combination and Postpartum Breast Care Aged One to Three Days on the Experience of Adequate Breastfeeding
Authors: Rahmatul Ulya Rahmatul Ulya , Panduragan Santhna Letchmi , Shentya Fitriana Shentya Fitriana , Che Hassan Hafizah
Published: October 2023

Introduction: Lack of breastfeeding in the first few days of life is an obstacle to early breastfeeding due to fear and anxiety about insufficient breastfeeding. A Proper breastfeeding experience can be enhanced through breast care, namely breast massage, nipple cleansing, and squeezing the breasts with warm and cold water. It naturally stimulates the breast to increase the hormone. Four out of 10 postpartum women complain that they are not producing enough milk for their babies. The purpose of this study was to examine the effects of a combination of lactation and breast massage care on postpartum breastfeeding production. Methods: A Quasi-experimental design with a one-group pretest- posttest design was used in this research. The population of this study was 32 respondents in total. Data collection in this study was carried out using researchers assessing the adequacy of breastfeeding before the intervention of a combination of lactation massage and breast care on postpartum aged one day and reassessing after being given a combination intervention of lactation massage and breast care on postpartum aged three days. Results: The average value of breastfeeding adequacy before being given a massage combination is 1.16, the average after being given a massage combination is 6.25, the average difference before and after is 5.09, and the p-value = 0.000. Conclusion: It can be concluded that the combination of lactation massage and breast care affects the adequacy of breastfeeding, with p value 0.000 (p <0.05).