bluuebunny/crossref_metadata_2025 huggingface dataset:
State of Anemonoides altaica (C.A. Mey.) Holub cenopopulations in the south-east of the natural area
Authors: Ilyina Valentina N.
Published: January 2022

Population ontogenetic studies are an important component of bioecological monitoring. The ontogenetic structure plays a role in determining the current state of natural populations, assessing the rarity status of a species in the region and throughout its range, and predicting the further development of the species. In the Samara region, natural cenopopulations of Anemonoides altaica (C.A. Mey.) Holub were studied on the territory of the Trans-Volga region (Sokol'ya mountains). According to the delta - omega criterion, most of them are mature, some are transitional and young. The revealed features of the ontogenetic structure and the calculated demographic indices of populations indicate the undoubted rarity and vulnerable position of the species in the region.
Purification of wastewater of industrial enterprises from phenols by modified energy waste
Authors: Nikolaeva Larisa A. , Aikenova Nuriya E. , Demin Alexey V.
Published: January 2022

With the development of engineering and technology, industrial enterprises have an increasing impact on the environment. One of the problems of our time is the pollution of water bodies with industrial toxic waste. Innovative in the field of environmental protection are methods of using inexpensive adsorbents for wastewater treatment, where cost factors play a major role. For quite a long time, an urgent task has been the development of inexpensive adsorbents that can be alternative to those existing at wastewater treatment facilities. Inexpensive alternative adsorbents can be obtained from a wide range of raw materials that are abundant, cheap, and highly absorbent. The article discusses the possibility of purification of industrial wastewater from phenols of oil refining industries on the example of LLP Aktobe Oil Refining. In the treatment of industrial wastewater, the method of adsorption treatment is widely used, which allows not only to purify from pollutants to maximum permissible concentrations (maximum permissible concentrations), but is also cost-effective when introduced. Economic efficiency is characterized by the use of industrial waste as adsorption materials, which in turn show high cleaning efficiency and resolve the issue of disposal of production waste. In this work, energy waste is used as an adsorption material - carbonate sludge from the chemical water treatment of the Aktobe TPP. To achieve a high degree of purification from pollutants, a modified carbonate sludge was obtained, which is used as an adsorption material in filters. A method for obtaining modified carbonate sludge from chemical water treatment is considered. A basic technological scheme of wastewater treatment from phenols has been proposed, a sorption filter for wastewater treatment with a filler - modified carbonate sludge has been selected and calculated. To implement the technology of purification of wastewater from phenols, the economic efficiency and the prevented environmental harm were calculated using the example of the enterprise LLP Aktobe Oil Refining. The technology of regeneration of waste carbonate sludge is considered. The heat effects of combustion of spent carbonate sludge as a fuel material are calculated using the example of Aktobe TPP.
Weierstrass Polynomials in Estimates of Oscillatory Integrals
Authors: Ikromov I. A. , Sadullaev A. S.
Published: January 2022

In this paper, estimates are obtained for the Fourier transform of smooth charges (measures) concentrated on some nonconvex hypersurfaces. The summability of the maximal Randall function is proved for a wide class of nonconvex hypersurfaces. In addition, in the three-dimensional case, estimates are obtained depending on the Varchenko height. The accuracy of the obtained estimates is proved. The proof of the estimate for oscillatory integrals is based on the Weierstrass preparatory theorem.
Penakwilan Ayat-Ayat Sifat menurut Imam Fakhruddin Al-Razi
Authors: Djuned Muslim , Makmunzir Makmunzir
Published: January 2022

One of the most controversial themes in the history of the interpretation of the Qur`an is the interpretation of the verses of the Qur`an related to the attributes of Allah Swt. Fakhr al-Dȋn al-Rȃzȋ was a commentator who interpreted the verses of nature. This study aims to find out the interpretation and approach used by Fakhr al-Dȋn al-Rȃzȋ in interpreting the verses of nature. The adjective verses that are the focus of the author here are the pronunciation of istawȃon QS. Ṭhȃhȃ: 5, yad on QS. al-Fatḥ: 10, wajh on QS. al-Rahmȃn: 27, ‘ain on QS. Hȗd: 37, and sȃq on QS. al-Qalam: 42. These words were chosen because they were widely discussed by the scholars in their works, especially in the treasures of Qur`anic Studies. The conclusions that can be drawn from this study are: First, Fakhr al-Dȋn al-Rȃzȋ tends to use takwȋl in understanding the verses of nature that is not to interpret the meaning of a sentence with the meaning that is apparent because there are arguments that prevent it from being interpreted with the meaning. Second, it tends to use language and logic approaches in interpreting adjective sentences.
Tafsir dan Budaya Aceh
Authors: Usman Iskandar
Published: January 2022

Tulisan ini bertujuan untuk mengkaji fenomena perkembangan tafsir di Aceh.Penelitian ini bersifat kualitatif dengan teknik pengumpulan data dokumentasi dan menggunakan metode deskriptif analitis, dengan melihat literatur dan sejarah keilmuan di Aceh. Hasil penelitian menunjukkan bahwa kajian tafsir di Aceh tidak terlalu berkembang sebagaimana fikih. Bahkan ada kevakuman yang lama setelah kitab Turjuman al-Mustafid yang ditulis oleh Abdurrauf al-Singkili. Beberapa masa setelahnya, mulai muncul karya-karya ulama yang mulai fokus mengkaji dan menulis tentang tafsir al-Qur’an.
Peasant Diaries and Folk Theme in L.N. Tolstoy’s Creative Laboratory of the 1870s
Authors:   A.M. Gorky Institute of World Literature of the Russian Academy of Sciences, Sizova Irina I.
Published: January 2022

The article examines the folk theme in Leo Tolstoy’s historical works of the 1870s; for the first time, materials from the diaries of Yasnaya Polyana peasants D.D. Kozlov and A.R. Bocharov are introduced into scientific circulation, and their reception in the writer’s work is revealed. The structure of the work is maintained in a certain sequence. The manifestation of the peasant theme is first considered in the entries of notebooks and diaries of the indicated period. Then, in this key, the novels about Russian bogatyrs, from the times of Peter I, “The Decembrists”, “One Hundred Years”, “Toiling and Burdened” are analyzed. Excerpts from the diaries of D.D. Kozlov and A.R. Bocharov, the most significant for understanding the artist’s creativity and worldview, are given in the “Appendix”. On a broad biographical and artistic basis, it is concluded that the diaries of D.D. Kozlov and A.R. Bocharov influenced Tolstoy’s understanding and artistic expression of the peasant theme. Features of the author’s awareness of the concept of “people” reveals the complex of aspects: the dynamics of the development of the category of nationality in the poetics, aesthetics, historiosophy of Tolstoy, principles of the formation of peasant images, the issue of their prototypes. In the artist’s legacy, the people act as the engine of history, as the creator, carrier and guardian of language and culture.
Tolstoy’s Book “The Reading Circle”: The Genre Issue
Authors:   Tver State University, Nikolaeva Svetlana Yu.
Published: January 2022

Tolstoy’s book “The Reading Circle” is considered as a complete, original literary work of a complex genre nature, in which artistic, journalistic, and philosophical principles are synthesized and the writers fully formed, integral plan is embodied. Only under this condition can the analysis of the book in the aspect of its problems, composition, poetics, sources, and textual theory be fruitful and correct. Special attention is paid to the calendar structure and genre of the philosophical fragment, which under Tolstoy’s pen is transformed from a lapidary aphorism into a “poem in prose” and becomes a structural element of the whole of the entire book.
A Contemporary Outlook on Wireless Sensor Networks for Solar Power Harvesting
Authors: Jacob Raglend , Ghanishtha Bhatti , Swaminathan Jose , Vincent-Herald Wilson , J. Belwin Edward , R. Sitharthan
Published: January 2022

While solar energy has been an emerging source of renewable energy for many years now with various studies delving into building more robust and compact solar cells, their use as a power source for mobile and small machinery such as wireless sensor networks (WSN) is less discussed. However, with increasing global efforts in subsidizing more sustainable technology and energy, many studies have emerged in the past decade on building solar power based wireless sensor networks. The combination of novel harvesting circuits, mechanisms to obtain maximum possible power, smart power management algorithms and improving energy technology has provided the necessary framework for self-powered WSN nodes that have much longer lifetime. This paper reviews the newer proposed technology that aids the development of Solar Energy Harvesting Wireless Sensor Networks.
Comportamiento de consumo a raíz de la pandemia en Bucaramanga y AMB
Authors: Prieto - Cuentas Narcy Carolina , Theran - Barajas Carmen Elisa
Published: January 2022

La presente investigación, es de tipo exploratoria cualitativa y su objetivo es establecer cambios en el comportamiento de consumo en habitantes de Bucaramanga y su Área Metropolitana (AMB), durante la pandemia. Esta investigación se desarrolla a partir del establecimiento del panorama parcial de la investigación para “Comportamiento de consumo” con Scopus, desde el inicio de la propagación del virus (2020) hasta abril del año 2021; indicado las tendencias y cambios para la temática de estudio, desde la literatura en este periodo y su correlación con información primaria tomada desde la población económicamente activa de Bucaramanga y su AMB. Como principales hallazgos se tiene un incremento en el consumo de productos de la canasta familiar en un 45%, productos de aseo y limpieza (53%), una disminución en el consumo de licores en un 51%, productos para mascotas (34%), calzado y textiles (54%), electrodomésticos (37%) y cosméticos (50%). Los servicios turísticos y de entretenimiento presentan el mayor detrimento con una disminución del 77% y un 78% respectivamente. Concluyendo que en el territorio un 66% de los consumidores ha cambiado la forma de adquirir sus productos a raíz de la pandemia, de forma similar a la registrada en la literatura.
La Mortandad de las MiPyMEs en Colombia y México
Authors: Lima Vasquez Roselio , Duana Avila Danae
Published: January 2022

En el presente artículo se nutre de información obtenida en los medio de información oficial, así como de otras fuentes no primaria, esto con la finalidad de identificar el comportamiento de las MiPyMEs, tanto en México como en Colombia, particularmente en sus efectos respecto a la mortandad de las empresas o negocios que se identifican en ambas naciones, equiparando como una de la problemática más detonante, la falta de una administración financiera adecuada, lo cual indica que si se aplicara de manera eficiente, podrá disminuir de manera importante la deserción de estas, y se podrá fomentar de manera confiable su creación, desarrollo, consolidación, viabilidad, productividad, sostenibilidad, competitividad y sustentabilidad, incrementado su esperanza de vida, por ello, la intensión de identificar el comportamiento de las microempresas en estos dos países para localizar algunas factores que permitan disminuir y en su caso eliminar la mortandad de esta MiPyMEs.
La evolución e implementación de la marca país en Colombia y su internacionalización.
Authors: Sierra Rodriguez Olga Marina , Infante Rivera Jhon Edinson
Published: January 2022

Varios son los modelos y forma de organizaciones, pero un país es el más complejo de las modalidades existentes. Gran parte de los países del mundo tienen un problema con la percepción de imagen a nivel internacional, que les impide mostrar y destacar todo lo bueno de su economía y cultura. Esta problemática se vuelve difícil de solucionar adecuadamente, por lo cual es necesario utilizar estrategias que cambien la percepción negativa ante los demás. El objetivo de este artículo de reflexión es analizar las diferentes opiniones, basados en datos y bibliografías referentes a la evolución e implementación de la marca país en Colombia y su internacionalizacion
ACQUIRED DOUBLE PYLORUS PRESENTING AS A GASTROINTESTINAL BLEEDING
Authors: Laabidi Sarra , Mohamed Asma Ben , khsiba amal , Yakoubi Manel , Mahmoudi Moufida , Medhioub Mouna , Hamzaoui Lamine , Azzouz Mohamed Msaddak
Published: January 2022

Gastroduodenal fistula (GDF) is a rare endoscopy finding that can be
acquired or congenital. We present the case of a 65-year-old male
without medical past history who was admitted for gastrointestinal
bleeding secondary to peptic ulcer. The case shows an acquired double
pylorus, due to pre pyloric ulcer.
Neuroendocrine Adenoma of Middle Ear Masquerading as a Middle Ear Vascular Lesion On Clinical Picture: Case Report and Review of Literature
Authors: zahid rafia , Menon Abhishek , Larem Aisha , Haider Hasan
Published: January 2022

Middle ear Neuroendocrine adenomas are rare tumors that can be easily
confused as glomus tympanicum of the middle ear. 33-year-old man with no
comorbidities who presented with complaints of right ear foreign body
sensation and was later diagnosed as a neuroendocrine adenoma of the
middle ear.
Proline-2′-deoxymugineic acid, active Fe chelator enhance peanut yield by integrated improving soil-plant Fe status at molecular and ecological level
Authors: Wang Tianqi , Wang Nanqi , Suzuki Motofumi , Lu Qiaofang , Lang Shanshan , Wang Kunguang , Niu Lei , Zuo Yuanmei
Published: January 2022

Iron (Fe) deficiency restricts crop yields in calcareous soil. Thus, a
novel Fe chelator, proline-2′-deoxymugineic acid (PDMA), based on the
natural phytosiderophore 2′-deoxymugineic acid (DMA), was developed to
solve the Fe deficiency problem. However, the effects and mechanisms of
PDMA relevant to the Fe nutrition and yield of dicots grown under field
conditions require further exploration. In this study, pot and field
experiments with calcareous soil were conducted to investigate the
effects of PDMA on the Fe nutrition and yield of peanuts. The results
demonstrate that PDMA could dissolve insoluble Fe in the rhizosphere and
up-regulate expression of the yellow stripe-like family gene
AhYSL1 to improve the Fe nutrition of peanuts. Moreover, the
chlorosis and growth inhibition induced by Fe deficiency were
significantly diminished. Importantly, under field conditions, the
peanut yield and kernel micronutrition were notably promoted by PDMA
application. Our results indicate that PDMA promotes the dissolution of
insoluble Fe and a rich supply of Fe in the rhizosphere, increasing
yields through integrated improvements in soil–plant Fe nutrition at
the molecular and ecological levels. In conclusion, the efficacy of PDMA
for improving the Fe nutrition and yield of peanut indicates its
outstanding potential for agricultural applications.
Elevational differences of the two closely related Taxus species in sympatric, evidence from species distribution modeling
Authors: Wu Xingtong , Wang Minqiu , Li Xinyu , Yan Yadan , Dai Minjun , Xie Wanyu , Zhou Xiaofen , Zhang Donglin , Wen Yafeng
Published: January 2022

Climate change is considered to affect the species distribution deeply
in time and space. Knowledge of how plant distribution responded to
climate change may help us know their evolutionary history and predict
ongoing environmental changes. Elevational range shifts of species in
response to climate change is a common phenomenon in mountains,
especially for the closely related species in sympatric. Here, we
selected Taxus chinensis and Taxus mairei to explore this issue. Four
types of environmental variables were used to simulate the distribution
patterns, under the historical climate and future climate change
scenarios, with the optimization Maxent model. We found that
elevational distribution of two species has significant differences. The
distribution of T. chinensis was higher than that of T. mairei. The
centroid of T. chinensis and T. mairei were in Sichuan and Hunan
province, respectively. Temperature and precipitation were the main
factors that determine the potential distribution of the two species,
and the suitable distribution area of T. chinensis was lower than T.
mairei. In the future, the direction of centroid migration of two
species was almost opposite, T. chinensis will shift southwest while T.
mairei go northeast. Our results not only provided an insight to
discriminate two sympatric species in subtropical and warm temperature
zones, but also gave us an important reference for the conservation of
these valuable endangered species.
From pattern to process? Dual travelling waves, with contrasting propagation speeds, best describe a self-organised spatio-temporal pattern in population growth of a cyclic rodent
Authors: Roos Deon , Caminero-Saldaña Constantino , Elston David , Mougeot Francois , García-Ariza María , Arroyo Beatriz , Luque-Larena Juan José , Revilla Francisco Rojo , Lambin Xavier
Published: January 2022

The dynamics of cyclic populations distributed in space result from the
relative strength of synchronising influences and the limited dispersal
of destabilising factors (activators and inhibitors), known to cause
multi-annual population cycles. However, while each of these have been
well studied in isolation, there is limited empirical evidence about how
the processes of synchronisation and activation-inhibition act together,
largely owing to the scarcity of datasets with sufficient spatial and
temporal scale. We assessed a variety of models that could be underlying
the spatio-temporal pattern, designed to capture both theoretical and
empirical understandings of travelling waves using large-scale
(> 35,000 km2), multi-year (2011-2017) field monitoring
data on abundances of common vole (Microtus arvalis), a cyclic
agricultural rodent pest. We found most support for a pattern formed
from the summation of two radial travelling waves with contrasting
speeds that together describe population growth rates across the region.
Relativistic Pure Rotational Energy for Diatomic Molecules
Authors: Aladrah Nicola , Almoukhalalati Adel , Dibo Suleiman
Published: January 2022

This paper provides a simplified solution of the Dirac equation for the
pure rotational energy of the diatomic molecules and a discussion of the
non-relativistic limit. The last works [1-2] led to a complicated
form of the relativistic energy of the molecular rotation-vibrational
energy with high computational cost based on Schrodinger-like equation.
The present work provides a way to determine the pure rotational energy
without exclusion of the wavefunction components or using the
Schrodinger-like equation, where the selection rule ΔJ=±1, where J is
the rotational quantum number, appears as a prerequisite for solving the
equations. Based on the anti-hermitian spin-orbit operator
(L) that been introduced in this paper, which
excludes the derivatives, the computational cost expects to decrease.
Validation of a Spanish Chronic Obstructive Sialadenitis Quality of Life Questionnaire
Authors: Coello Jessica Mireya Santillán , Barrueco Alvaro Sanchez , Galán Fernando González , Tapia Gonzalo Diaz , Fernández Ignacio Mahillo , Español Carlos Cenjor , Aubá José Miguel Villacampa
Published: January 2022

Objectives: To design a Spanish questionnaire to assess quality of life
in chronic obstructive sialadenitis (COS), named CSOC and assess its
reliability, validity and feasibility. Design: A prospective,
multicentre, observational study Settings: Salivary Gland Disorder and
Sialendoscopy Unit, University Tertiary Hospital. Participants: Patients
with diagnosis of COS and indication for sialendoscopy were included in
the study. Main outcome measures: The item generation process included a
review of published data as well as interviews with patients. An expert
panel then tested the content validity of the instrument and the
construct validity was tested in 120 patients. Patients completed a
self-administered CSOC questionnaire, a Short Form-36 and a Visual
Analogue Scale. Feasibility, reliability, internal consistency,
construct validity and responsiveness were assessed. Results: All the
patients found the instrument understandable. Cronbach α coefficient was
high (0.85). The time required to fill out was 5.7 and 4.5 minutes for
pre and postsialendoscopy CSOC respectively. Cronbach α coefficient was
very high for both pre and postsialendoscopy CSOC (0.90 and 0.94
respectively). The correlation with the SF-36 dimensions was negative
and positive with the VAS. The mean score of CSOC was 28.6 and 7.98 for
pre and postsialendoscopy Conclusions: The CSOC questionnaire is
understandable, feasible, reliable and representative of quality of life
in COS. Keywords: sialadenitis, QOL, questionnaire, validation,
sialendoscopy
Lamin heart disease with ventricular noncompaction and complex atrial septal arrhythmias: successful use of charge density mapping.
Authors: Scharf Christoph , Caselli Stefano , Dang Lam , Mayer Kurt , Jost Christine Attenhofer
Published: January 2022

Lamin A/C Mutations are important to recognized for therapeutic and
prognostic reasons. We present the clinical cases of two sisters with
Lamin A mutation presenting with complex atrial arrhythmias,
atrioventricular block and ventricular arrhythmias, associated with
ventricular noncompaction and abnormal pulmonary vein anatomy. The
successful treatment of complex irregular atrial arrhythmias by the use
of noncontact dipole density mapping and radiofrequency ablation (RFA)
is described in both sisters with long-term follow up results.
EP matrices of adjointable operators on Hilbert C*-modules
Authors: Li Xiaopeng , Huang Junjie , Chen Alatancang
Published: January 2022

In this paper, we investigate EP modular operator matrices on Hilbert
C*-modules setting. The necessary and sufficient conditions for some modular
operator matrices to be EP are discussed, based on the generalized Schur
complement. These enable us to generalize some results of Meenakshi (1958)
[11] for block matrices.
A numerical technique for solving a class of nonlinear singularly perturbed boundary value problems
Authors: Barati Ali , Nabati Mohammad
Published: January 2022

In this work, we have studied a numerical scheme based on Sinc collocation
method to solve a class of nonlinear singularly perturbed boundary value
problems. The solution of the problems exhibit a boundary layer on the both
sides or one side of the domain due to the presence of perturbation
parameter ?. The Sinc method can control the oscillations in computed
solutions at boundary layer regions naturally because the distribution of
Sinc points is denser at near the boundaries. The convergence analysis is
discussed and the method is shown to be an exponential convergent. The
numerical results support the theoretical results and illustrate the
efficiency and accuracy of the method compared with the results in the
existing methods.
Quantum Hermite-Hadamrd-Fejér type inequalities for (σ,h)-convex functions
Authors: Nefzi Bochra , Riahi Latifa , Awan Muhammad , Dragomir Silvestru
Published: January 2022

The aim of this article is to establish some new quantum analogues of
Hermite-Hadamard-F?jer type inequalities involving Riemann type of quantum
integrals. In order to obtain the main results of the paper, we use the
classes of harmonically convex functions, ?-convex functions and (?,h)-convex functions.
The effect of nitrogen-doped titanium dioxide–modified stainless steel brackets on Streptococcus mutans:
Authors: Monica Avula , Padmanabhan Sridevi
Published: January 2022

Objectives

To evaluate the effect of nitrogen (N)-doped titanium dioxide (TiO2) coated stainless steel brackets activated with natural visible light and dental operating lights on Streptococcus mutans concentration in the plaque of orthodontic patients at 30 and 60 days.

Materials and Methods

A total of 30 patients were recruited for this split-mouth study; 60 upper lateral incisor brackets constituted the study sample. A total of 30 brackets (15 right and 15 left) were coated with N-doped TiO2 using the (radio frequency) magnetron sputtering method. Plaque samples were collected at 30 days and 60 days after appliance placement. S mutans concentration was evaluated using real-time polymerase chain reaction.

Results

At both time intervals, the concentration of S mutans in the control group was greater than that in the study group (P = .005). In both the study and the control groups, the S mutans concentrations significantly increased from 30 to 60 days (P = .005).

Conclusions

N-doped TiO2, on exposure to natural visible light and dental operating light, was effective in reducing the plaque concentration of S mutans in orthodontic patients. The efficacy was better at 30 days than at 60 days after placing the orthodontic appliances.
Sulfated Progesterone Metabolites That Enhance Insulin Secretion via TRPM3 Are Reduced in Serum From Women With Gestational Diabetes Mellitus
Authors: Fan Hei Man , Mitchell Alice L. , Bellafante Elena , McIlvride Saraid , Primicheru Laura I. , Giorgi Mirko , Eberini Ivano , Syngelaki Argyro , Lövgren-Sandblom Anita , Jones Peter , McCance David , Sukumar Nithya , Periyathambi Nishanthi , Weldeselassie Yonas , Hunt Katharine F. , Nicolaides Kypros H. , Andersson David , Bevan Stuart , Seed Paul T. , Bewick Gavin A. , Bowe James E. , Fraternali Franca , Saravanan Ponnusamy , Marschall Hanns-Ulrich , Williamson Catherine
Published: January 2022

Serum progesterone sulfates were evaluated in the etiology of gestational diabetes mellitus (GDM). Serum progesterone sulfates were measured using ultra-performance liquid chromatography–tandem mass spectrometry in four patient cohorts: 1) the Hyperglycemia and Adverse Pregnancy Outcomes study; 2) London-based women of mixed ancestry and 3) U.K.-based women of European ancestry with or without GDM; and 4) 11–13 weeks pregnant women with BMI ≤25 or BMI ≥35 kg/m2 with subsequent uncomplicated pregnancies or GDM. Glucose-stimulated insulin secretion (GSIS) was evaluated in response to progesterone sulfates in mouse islets and human islets. Calcium fluorescence was measured in HEK293 cells expressing transient receptor potential cation channel subfamily M member 3 (TRPM3). Computer modeling using Molecular Operating Environment generated three-dimensional structures of TRPM3. Epiallopregnanolone sulfate (PM5S) concentrations were reduced in GDM (P < 0.05), in women with higher fasting plasma glucose (P < 0.010), and in early pregnancy samples from women who subsequently developed GDM with BMI ≥35 kg/m2 (P < 0.05). In islets, 50 µmol/L PM5S increased GSIS by at least twofold (P < 0.001); isosakuranetin (TRPM3 inhibitor) abolished this effect. PM5S increased calcium influx in TRPM3-expressing HEK293 cells. Computer modeling and docking showed identical positioning of PM5S to the natural ligand in TRPM3. PM5S increases GSIS and is reduced in GDM serum. The activation of GSIS by PM5S is mediated by TRPM3 in both mouse and human islets.
Immune and Metabolic Effects of Antigen-Specific Immunotherapy Using Multiple β-Cell Peptides in Type 1 Diabetes
Authors: Liu Yuk-Fun , Powrie Jake , Arif Sefina , Yang Jennie H.M. , Williams Evangelia , Khatri Leena , Joshi Mamta , Lhuillier Loic , Fountoulakis Nikolaos , Smith Emma , Beam Craig , Lorenc Anna , Peakman Mark , Tree Timothy
Published: January 2022

Type 1 diabetes is characterized by a loss of tolerance to pancreatic β-cell autoantigens and defects in regulatory T-cell (Treg) function. In preclinical models, immunotherapy with MHC-selective, autoantigenic peptides restores immune tolerance, prevents diabetes, and shows greater potency when multiple peptides are used. To translate this strategy into the clinical setting, we administered a mixture of six HLA-DRB1*0401–selective, β-cell peptides intradermally to patients with recent-onset type 1 diabetes possessing this genotype in a randomized placebo-controlled study at monthly doses of 10, 100, and 500 μg for 24 weeks. Stimulated C-peptide (measuring insulin functional reserve) had declined in all placebo subjects at 24 weeks but was maintained at ≥100% baseline levels in one-half of the treated group. Treatment was accompanied by significant changes in islet-specific immune responses and a dose-dependent increase in Treg expression of the canonical transcription factor FOXP3 and changes in Treg gene expression. In this first-in-human study, multiple-peptide immunotherapy shows promise as a strategy to correct immune regulatory defects fundamental to the pathobiology of autoimmune diabetes.
Reducing patient–staff contact in fast-track total hip arthroplasty has no effect on patient-reported outcomes, but decreases satisfaction amongst patients with self-perceived complications: analysis of 211 patients
Authors: Hansen Jens B , Sørensen Jens F L , Glassou Eva N , Homilius Morten , Hansen Torben B
Published: January 2022

Background and purpose: Several studies have compared fast-track with conventional pathways for total hip arthroplasty (THA) patients, but none have compared different fast-track pathways. Due to COVID-19 restrictions, our department had to minimize patient–staff contact in the THA pathway. First, telephone consultations were implemented instead of an outpatient clinic visit and subsequently preoperative patient education was discontinued. This enabled us to compare patient-reported outcomes and satisfaction among 3 fast-track pathways.
Patients and methods: We collected data from patients treated for hip osteoarthritis with THA at Gødstrup Hospital between 2018 and 2021. The patients had experienced 1 of 3 pathways and were interviewed via telephone between 2 and 6 months after discharge. We analyzed the influence of patient pathway on patient-reported pain and mobility level, self-perceived complications, and compliance using logistic regression. We then compared the pathway’s effect on patient satisfaction both for the total sample and for the patients who experienced complications.
Results: The amount of patient–staff contact in the patient pathway did not have any influence on patientreported outcomes or the probability of self-perceived complications. For the full sample, patient–staff contact had no statistically significant influence on patient satisfaction either, but for the subgroup of patients experiencing complications, the pathways with less patient–staff contact reducedsatisfaction. Patient satisfaction was primarily related to pain and mobility outcomes.
Interpretation: Our results indicate that reducing patient–staff contact in fast-track THA can be done without influencing mobility and pain outcomes, but the overall satisfaction among patients with self-perceived complications will be negatively affected.
escrita no Ensino Médio
Authors: Souza Moisés José Rosa , Arena Dagoberto Buim , Moreira Melissa Velanga
Published: January 2022

Este artigo refere-se à escrita de enunciados do gênero artigo de opinião e objetiva averiguar o desenvolvimento linguístico que ocorre nos alunos em atividade no ato de escrever. O fundamento teórico é a teoria da Filosofia da Linguagem, cuja linguagem é social, dinâmica e evolutiva no tempo e no espaço. A pesquisa envolveu sete alunas do Ensino Médio, em que demostramos e discutimos como os enunciados escritos foram se formando e ganhando substância linguística e de conteúdo. Como resultado, indica-se o desenvolvimento da escrita como ação que contribui para a expansão do domínio da expressão escrita dos envolvidos no processo.
Investigando ideologias linguísticas sobre o “falante nativo” em um livro didático local de inglês uma análise de base documental
Authors: Monteiro Mariana Nunes
Published: January 2022

Na contemporaneidade, as misturas linguístico-identitárias tornam-se cada vez mais latentes, dificultando a delimitação de uma língua a uma determinada comunidade. Dessa forma, faz-se necessário pensar em uma linguística das práticas e dos contatos em oposição a uma linguística das comunidades (MOITA LOPES, 2013). Entendendo essas necessidades, o grupo de pesquisa do qual fiz parte na escola federal onde atuei como professora substitua de inglês por dois anos, desenvolveu um projeto de ensino de língua inglesa pensando seu lugar na contemporaneidade. O presente estudo, qualitativo interpretativista e de base documental, parte integrante desse projeto, focaliza a análise das quatro primeiras seções de leitura do livro didático It fits 8, destinado ao 8º ano do Ensino Fundamental II. O principal objetivo é observar de que maneira o material parece “refletir” e “refratar” (Vólochinov, 1929 [2017]) a figura do dito falante nativo e como, consequentemente, posiciona o aluno que o utiliza em relação à língua inglesa. Fez-se necessária essa análise para que possíveis adaptações do material pudessem ser propostas ou até mesmo para que pudéssemos pensar sobre a viabilidade de produzirmos o nosso próprio material didático.  A fim de alcançar os objetivos propostos, me debruço sobre os seguintes pressupostos teórico-metodológicos: ideologias linguísticas sobre a língua inglesa e sobre o falante nativo, livros didáticos (locais) para o ensino de inglês, e PNLD. A análise, embasada por alguns dos macrocritérios para a análise de livros didáticos (TILIO, 2016), aponta para a potencialização da episteme do falante nativo de inglês como o objetivo a ser alcançado pelos aprendizes brasileiros, o que acabou indicando a necessidade da produção de um material próprio que desconstruísse o ideal do falante nativo e incentivasse os usos criativos da língua.
Fundamentos da Ética segundo Peirce
Authors: Bueno Felipe
Published: January 2022

O presente artigo pretende realizar um breve ensaio sobre os aspectos fundamentais da Ética segundo o esquema filosófico de Charles Sanders Peirce, filósofo estadunidense que atuou entre os séculos 19 e 20. Com este propósito, se fez indispensável a incursão tanto nos manuscritos de Peirce, conferidos nos Collected Papers (Harvard University Library Photographic Service, 1966) e em manuscritos ainda não publicados, quanto nas pesquisas de estudiosos que se debruçaram sobre este tema.  Ainda, as noções mais gerais que envolvem a estrutura da filosofia peirceana, como a Fenomenologia e a particularidade triádica do signo, tornaram-se balizas das construções lógicas e da costura teórica deste exame sobre a Ética. Portanto, almeja-se abordar essas ideias dando destaque às facetas da noção de signo, da semiose e da atuação do Ideal Supremo, o summum bonum, em relação aos ideais de conduta, pontos centrais que esboçam a excepcionalidade da Ética segundo Peirce.
Variations of the branches arising from the third part of the axillary artery: a cadaveric study
Authors: Alashkham Abduelmenem , Almabrouk Tarek , Soames Roger
Published: January 2022

Objectives: This study aims to describe variations of the third part of the axillary artery branches with respect to their diameter, origin, subsequent branches, and gender. Methods: One-hundred and forty cadaveric shoulders were examined bilaterally in the Centre for Anatomy and Human Identification, University of Dundee, which is regulated by Human Tissue Act (Scotland) 2006. Branches arising from the third part of the axillary artery were dissected and the diameter, origin, subsequent branching patterns of each branch were documented, as well as gender. T-tests and chi-square tests were used to determine the association between the variables. Results: The most common variations were associated with the posterior circumflex humeral artery (48.3%), followed by the anterior circumflex humeral (25%) and subscapular arteries (16.7%). Variations of the anterior circumflex humeral artery were more common in females than males (p<0.05). A significant association between the origin of posterior circumflex humeral artery and its subsequent branching pattern was observed. In females, the anterior circumflex humeral artery was more likely to give rise to the profunda brachii when it originated from the posterior circumflex humeral artery. Conclusion: Branches of the third part of the axillary artery vary in diameter, origin and subsequent branching patterns and the gender. An understanding of these variations is essential for accurate radiological diagnostic interpretation and therapeutic intervention. The difference in the variations observed and those reported in the literature suggest the need for further large scale studies.
The anatomical relationship between recurrent laryngeal nerve and high inferior thyroid artery: a case report
Authors: Özen Kemal Emre , Erdoğan Kübra , Ay Keselik Gonca , Malas Mehmet Ali
Published: January 2022

In this case report, we present a case with an unusually high course of inferior thyroid artery and its relationship with the recurrent laryngeal nerve on the right side of the neck of a 91 years-old formalin fixed male cadaver. Dissection showed that the inferior thyroid artery gave off branches between the branches of the recurrent laryngeal nerve following a sharp curvature descending downward to the thyroid gland. Knowledge of such a variation of the location and course of the inferior thyroid artery and the recurrent laryngeal nerve is important for surgical and radiological procedures.
Examination of presence and location of the accessory mental foramen, and its implications on the mental nerve block
Authors: Sevmez Fatma , Bahşi İlhan , Orhan Mustafa
Published: January 2022

Objectives: It is clinically essential to know the location of accessory mental foramen in the mental nerve anesthesia. The aim of this study was to determine the frequency of accessory mental foramen and examining its morphometric properties. Methods: A total of 35 adult mandibles of unknown age, gender, and ethnicity were examined. The presence of accessory mental foramen of the mandible was investigated bilaterally. In cases with the accessory mental foramen, its localization, number, and distance relative to the mental foramen were evaluated. Results: Eleven (15.71%) accessory mental foramens were detected in the 35 mandibles (70 sides) examined. Six (54.55%) of the accessory mental foramens were on the left side, and 5 (45.45%) were on the right side. Conclusion: Knowing the frequency and localization of the accessory mental foramen will make the mental nerve block more effective and facilitate surgical procedures. It should be kept in mind that the presence of accessory mental foramen should be considered in cases where mental nerve block applications are insufficient.
The role of social support in pandemic-related stress among university students
Authors: Sari Liliyana , Khaira Fathiyyatul
Published: January 2022

The COVID-19 pandemic lockdown has negatively impacted various aspects of university students’ lives which often leads to higher levels of stress. The current research aims to investigate the role of social support in pandemic-related stress among this population. A total of 121 university students in West Sumatra was recruited through convenience sampling to complete the Multidimensional Scale of Perceived Social Support and Pandemic-Related Perceived Stress Scale. The results showed that perceived social support had a significant role in reducing pandemic-related stress by 10.8% in which perceived support from friends was a better predictor than other sources of support. In addition, this study reported a significant difference in pandemic-related stress based on the income of parents where students from lower-income families had a higher prevalence of stress. The findings of this study propose that providing social support particularly from peers would hinder the perceived stress level of university students during the COVID-19 pandemic.
Analysis of perception and emotional condition from distance learning among undergraduate student during Covid-19 pandemic
Authors: Liza Rini Gusya , Fasrini Ulya Uti , Wati Westi Permata
Published: January 2022

Education minister changes learning methodby distance learning to prevent the spread of Covid-19. This change has an impact on the mentality of students. This research aims to analysis perception and emotional mental health of undergraduate students at the Faculty of Medicine, Universitas Andalas during the Covid-19 pandemic. This research is cross-sectional study and obtained 344 respondents using simple random sampling from May to December 2020. The distance learning evaluation use questionnaire in google form and the results are quantitative data; the emotional mental health condition use SRQ-20 and Microsoft Excel. This result show that all respondents experienced mental emotional disorders. The most frequently is cognitive symptoms, but some students still enjoy because closed to their family and cost saving although they have some obstacles observed, both in terms of devices, signal, and lack of interaction. All of students have mental health disorder but distance learning has been running well.
Significance of emotional work-home spillover and harsh parenting during the Covid-19 pandemic
Authors: Angelica Celine , Pristinella Debri
Published: January 2022

The objective of this research is to find out whether positive and negative emotions transmitted from work while taking care of their children and assisting them during home-based learning, has any influence on parents’ harsh parenting towards children. Data was collected using JAWS and CTSPC instruments and received responses of 49 parents aged 20-59 years old, with children’s education level ranging from kindergarten to senior high school. The Data were analyzed using Spearman Correlation. The findings show no significant relationship between positive emotion and harsh parenting, as well as between negative emotion and harsh parenting. Several factors such as parents’ age, family economy, and children’s level of education may influence the findings, although the specific influence of these factors needs further research.
Virtually Impossible: Deleuze and Derrida on the Political Problem of Islands (and Island Studies)
Authors: Williams Stewart
Published: January 2022

: It is commonplace to think of an island as a discreetly bounded unit. Selected writings on islands by the poststructuralist philosophers Gilles Deleuze and Jacques Derrida reveal the island variously to be both real and imaginary, mythological and scientific, but as most problematic when constituted in political terms as an indivisible, sovereign entity. These two thinkers’ more broadly developed concepts of the virtual and the impossible, respectively, are seen to disrupt any assumptions about the fixity and closure of the island polity. Instead they emphasize its actualization through processual relations that can be difficult yet dynamic and decisive in effecting the move from being to becoming-other. As the possibilities for instituting more ethical as well as different political relations open up, the question of island studies remaining in its currently coherent, familiar form is raised for consideration.
‘Genuine Jersey’: Branding and Authenticity in a Small Island Culture
Authors: Johnson Henry
Published: January 2022

Jersey has attained a recognized international reputation especially in agriculture, tourism and finance. Over the past century, this small island has developed rapidly as a tourist destination and, since the 1960s, as a leading international finance centre. This paper discusses how a public-private organization uses a notion of islandness in order to help add value to local produce and products, and at the same time offering a sense of authenticity in terms of provenance. As an organization and brand, “Genuine Jersey” was launched in 2001 and is now a particularly visible island-based brand that does much to support local businesses and promote selected island produce and products more broadly to locals and visitors alike, as well as within a wider export industry. Drawing on discourses mainly from island studies and marketing, the article discusses how and why this brand exists on Jersey. While including a critical discussion of the brand itself, the paper shows how Genuine Jersey operates on and as a result of this particular island context.
Mapping the Outer Hebrides in sound: towards a sonic methodology
Authors: Lane Cathy
Published: January 2022

Scottish Gaelic is still widely spoken in the Outer Hebrides, remote islands off the West Coast of Scotland, and the islands have a rich and distinctive cultural identity, as well as a complex history of settlement and migrations. Almost every geographical feature on the islands has a name which reflects this history and culture. This paper discusses research which uses sound and listening to investigate the relationship of the islands’ inhabitants, young and old, to placenames and the resonant histories which are enshrined in them and reveals them, in their spoken form, as dynamic mnemonics for complex webs of memories. I speculate on why this ‘place-speech’ might have arisen from specific aspects of Hebridean history and culture and how sound can offer a new way of understanding the relationship between people and island toponymies.
Cedros: Origin and permanence of the placenames in a Mexican Pacific island
Authors: Israel Baxin Martínez Jesús
Published: January 2022

Toponymy is a field of knowledge that provides valuable support to pertaining to geography: it contributes to the naming of geographical space and its parts, and is a sign of the appropriation of territories by human groups. Mexican toponymy has diverse linguistic origins: most stem from indigenous languages and Spanish, and their combinations, on continental and island soils. The geographical names used to designate natural elements and places of itinerant or permanent occupation on island territories have been arbitrarily assigned in different historical eras. This paper analyzes the toponyms of the island of Cedros (Baja California, Mexico), their historical roots and the names assigned by its contemporary inhabitants. The toponyms discussed here are compared to some geographical names from the western shore of the Baja California peninsula and other Mexican islands.
Enduring perceptions: Placenaming and the perception of Louisiana’s salt dome islands
Authors: Hayward Philip
Published: January 2022

Salt domes are geological features that occur when areas of salt deposits are pressured into layers above them, causing dome shaped distortions in horizontal strata. In some instances, the distortions protrude above flat areas of land or else appear underwater as seamounts. In the case of the five Louisiana salt dome hills considered in this article, their distinct elevation above the swampy bayous and flatlands surrounding them has led to their characterisation as islands by indigenous Atakapa-Ishak peoples and by subsequent Francophone and Anglophone settlers. The article considers the ways in which the five salt domes’ islandness has been perceived, enhanced and/or undermined by various local inhabitants and/or the industries that have operated on them. Discussion of these aspects involves consideration of the manner in which the salt dome islands’ islandness is mutable and complex, particularly with regard to human impacts. This mutability is discussed with regard to both individual island placenames and the islands’ overall designations.