bluuebunny/crossref_metadata_2025 huggingface dataset:
Various sedimentary facies of tsunami deposits in the lowlands along the eastern margin of the Japan Sea, northern Hiyama District, Hokkaido, Japan
Authors: Kase Yoshihiro , Kawakami Gentaro , Nishina Kenji , Urabe Atsushi , Koyasu Hiromichi , Takashimizu Yasuhiro
Published: June 2022

A tsunami deposit investigation was conducted to verify the presence and source of tsunami deposits in northern Hiyama district, southwest Hokkaido, Japan. Three (Th-2–Th-4) and one (Ku-2) possible tsunami deposits were identified in the Hirahama and Kumaishi-Ayukawa lowlands, respectively. Th-2–Th-4 were divided into sands (Th-2) and gravels (Th-3–Th-4), although they were found in almost the same sites. These differences might have been in harmony with beach clastics as their sources during the Th-2 and Th-3–Th-4 events. It was possible that strong tsunami return flow eroded and transported sands seaward, leaving only gravels behind. Ku-2 consisted of volcanic-ash sands with the overlying silts and showed three fining-upward sequences (Units A–C). The modal compositions of Units B–C were distinct from beach and river sands, although that of Unit A was similar with beach and river sands. The chemical composition of volcanic glasses of Ku-2 indicate that volcanic-ash sands originated from reworked tephra. Considering the rounded clastics, landward paleocurrent, and high proportion of marine–brackish diatoms in Unit B, volcanic-ash sands might have been widespread in the seafloor as a provenance beyond the foreshore and were transported by tsunami run-up flow. Seaward paleocurrent of Unit C was interpreted as return flow. The sedimentary process of Unit A remains unclear because of lack of sedimentary structures and diatoms. Unit A might have been formed by a series of tsunami or lahar. Based on radiocarbon dating, tephrochronology, historical records, and known paleotsunamis in the adjacent area, Th-2 and at least Units B–C, Th-3, and Th-4 could be correlated with AD1741, 12th century, and 2.4–2.6 ka tsunamis, respectively. Considering turbidites in the Shiribeshi Trough, it is reasonable that ca 2–2.6 ka event deposits were formed by the same earthquake with accompanying tsunami. Further studies are needed on whether tsunami deposits—correlated with abovementioned tsunami event—existed in central Hokkaido or southern Hiyama District, where effects of tsunamis triggered by the active faults of F14/F15 and F17/F18 were much stronger, respectively. Confirmation of existence is expected to help clarify the activity record of tsunami sources in southwest Hokkaido.
D-dimer/albumin ratio is a prognostic marker for patients with aneurysmal subarachnoid hemorrhage-retrospective research
Authors: Wu Wei , Liu Xun-Zhi , Chen Xiang-Xin , Sheng Bin , Zhang Jia-Tong , Li Wei , Zhang# Ding-Ding , Hang# Chun-Hua
Published: June 2022

Background
Aneurysmal subarachnoid hemorrhage (aSAH) is a serious neurological disorder with limited treatment options and very little is known about its pathophysiology. And there are few available objective tools for predicting the clinical prognosis of aSAH patients and further aiding in directing clinical therapeutic programs. This study aimed to evaluate whether the raised serum D-dimer/albumin ratio (DAR) could reflect disease severity and predict clinical outcomes after aSAH.
Methods
A total of 178 patients with aSAH were included in this retrospective study. Collected data included demographics; clinical severity of aSAH (WFNS scale and Hunt-Hess scale), levels of D-dimer, albumin, c-reactive protein (CRP), leukocyte counts, mRS on admission; and three-month prognosis. Clinical prognosis was dichotomized into favorable outcome (mRS ≤ 2) and unfavorable outcome (mRS ≥ 3). And the predictive ability of DAR for aSAH prognosis was determined by Receiver Operating Characteristic (ROC) Curve analysis.
Results
The serum DAR showed a strong positive correlation with disease severity. Univariate analysis revealed that DAR, WFNS grade, Hunt-Hess grade, delayed cerebral infarction (DCI), age, neutrophil-to-lymphocyte ratio (NLR), and c-reactive protein/albumin ratio (CAR) were associated with unfavorable clinical outcome. Multivariate regression analysis further revealed that elevated DAR could predict poor prognosis after correcting for WFNS grade, Hunt-Hess grade, DCI, age, NLR, and CRP/albumin ratio. The receiver operating characteristic curve result demonstrated that DAR was a comparable predictor for clinical outcome of aSAH in comparison with NLR and CAR.
Conclusion
DAR was d promising objective tool for aSAH patients. Hight content DAR was associate with disease severity and unfavorable short-term prognosis.
Nighttime warming affected grain yield components, Cu accumulation and translocation of wheats grown in Cu-contaminated soil
Authors: Cheng Xianghan , Liu Feifei , Liu Xiaolei , Chen Xianni , Kou Taiji
Published: June 2022

Amis
This study aimed to uncover the changes in yield components, Cu accumulation and translocation of wheats in response to Cu pollution under nighttime warming.
Methods
Pot trials were adopted with two level of ambient temperature (no-warming (NT) and warming (WT)) and two level of soil Cu content (control check without Cu application (CK) and 100 mg/kg Cu application (Cu)). Canopy temperature, biomass, yield components, Cu content, accumulation and translocation factors of wheats, available Cu content and enzyme activities in soil were determined throughout the wheat growth period.
Results
Warming effect of passive nighttime warming system was prominent and average increment was 0.28°C. The highest yield was achieved in NT-Cu by many more spikes per pot and grains per spike, but the Cu content in its grains could present a potential risk to food security. Though Nighttime warming didn’t increase the total biomass and yield of wheats, soil urease and catalase activities, it decreased Cu accumulation of wheats grown in Cu-contaminated soil, especially in grains. Moreover, warming treatments increased the Cu content in the roots and glumes, reduced the content in grains. Among them, Cu content of grains in WT-Cu was the lowest and significantly lower than other applications.
Conclusions
Our findings reveal that nighttime warming has the potential to weaken the Cu risk of grains in wheats grown in Cu-contaminated soil.
Response of habitat quality to land use change in urban built-up area of karst mountainous city
Authors: Wei Wenfei , Wang Zhitai , Bao Yu , Chen Xintong , Sun Yuzhen , Zeng Mulin , Mo Yaguo
Published: June 2022

There are a large number of urban remnant mountains (URMs) in the built-up areas of karst mountainous cities, which are the main components of urban habitats and play a variety of irreplaceable ecosystem services functions such as maintaining local biodiversity. Based on InVEST model and geographically weighted regression (GWR), this study explored the relationship between land use/land cover (LULC) and habitat quality (HQ) evolution in a typical karst mountainous city. The results showed that: (1) the LULC change in the study area was intense from 2008 to 2018, with cultivated land and URMs transformed into construction land, and the urban landscape fragmentation was serious. (2) The overall level of HQ in the study area was low. The high value area was mainly distributed in the area where large urban green space (UGS) and URMs were located, while the low value area was mainly concentrated in the construction land gathering area. (3) GWR analysis showed that there was a significant correlation between LULC change and HQ change, natural environment determined the overall distribution of HQ, and human activities played a leading role in HQ change. (4) URMs was the main contributor of high level HQ, but its encroachment by construction land and the increase of surrounding building density make the quality of URMs habitat degraded obviously. This study is of great significance for urban biodiversity conservation and urban high-quality development.
A TTN-mutation-associated gene signature for prognostic prediction of hepatocellular carcinoma
Authors: Bi Yanqing , Huang Rong , Zhang ziying , Tian Zixuan , Liu min , Bao Han , Yan tao , Xia Yuan , Zhang nan , Zhang xingguang
Published: June 2022

Background: Mutation in titin (TTN), associated with a worsened prognosis, is among the most common genetic variants in human hepatocellular carcinoma. mRNA expression data and TTN mutation information from TCGA cohort were utilized to characterize a specific TTN-mutation-associated signature according to gene-expression differences between wild type (TTN-WT) and TTN-mutated (TTN-MUT) hepatocellular carcinoma (HCC) patients. In total, 189 differentially expressed genes (DEGs) potentially correlated with TTN mutation status were identified. Methods: Five genes (VAX1, MMP3, CXCL5, TKTL1 and KCNA3), identified by univariate Cox regression and Kaplan-Meier survival analyses, constituted an independent OS prognostic gene signature in HCC patients. Depending on this gene signature, patients were grouped into high- and low-risk subgroups and a significant enrichment associated with immunity is detected between the risk groups. In addition, the high-risk group was associated with an abundance of macrophages and neutrophils, while the infiltration indices of T follicular helper cells, natural killer cells, and type 2 helper T cells (Th2) were lower compared to low-risk group. In the multivariate Cox regression model, the five-gene signature remained a significant predictor independent of other conventional clinical risk factors used for survival prediction in HCC patients. MMP3 and CXCL5 expression were further validated in HCC cell lines.Results: We established a novel and unique TTN-mutation-related gene signature for survival outcome prediction for HCC patients. Conclusion: Our research foundings display a specific mechanism of TTN mutation and hold promise for the identification of HCC patients with poor prognosis.
Association of Non-carious Cervical Lesions With Oral Hygiene Aspects and Oclusal Force
Authors: Werneck Rafael Dario , Queiroz Daher Antonio , Rio Diana Leyva del , Altdorfer Balint Timothy Gabor , Turssi Cecilia Pedroso
Published: June 2022

One of the theories that contribute to explaining the evolution of non-carious cervical lesions (NCCLs) refers to fatigue wear, in which the concentration of stresses in the cervical region leads to the formation of microfractures in the dental tissues and progressive structure loss. However, due to a combination of factors that may cause wear, there is still uncertainty about the role of the occlusal factor as a risk factor that causes NCCLs. Objectives: The purpose of this case-control study was to investigate the association between the presence of NCCLs with occlusal force and other potential risk factors. Materials and Methods: Thirty-nine participants with NCCLs (cases) and 39 non-carrier patients (control), aged between 20 and 59 years old, were enrolled in the dental clinic of the Faculdade Integradas São Pedro (FAESA), located in Vitória, Espírito Santo State, Brazil. Information was collected through anamnesis, clinical examination, and a questionnaire addressing aspects related to tooth brushing, dentifrice, and mouthwash use. In clinical examination, patients were submitted to four measurements of occlusal force in the maxillary first premolars and maxillary first molars, using a strain gauge sensor of medium intensity, the Flexiforce (Tekscan, South Boston, MA, USA). The sensor was calibrated for the unit of measurement in Newtons (N). Results: Data was analyzed using a Student's t-test and multiple logistic regression, adopting the significance level of 5%. There was no statistically significant difference between the case and control groups regarding the bite force in the four measured regions. Logistic regression identified sex as a factor significantly associated with non-carious cervical lesions (p = 0.020). For the calculation of the odds ratio, the female sex presented a six-fold chance (OR = 6.082; CI = 1.332 - 27.765) higher than non-carious cervical lesions. Conclusions: It was concluded that females presented a higher risk factor for non-carious cervical lesions than men, whereas there was no association of occlusal strength, as well as aspects related to brushing and deleterious habits.Clinical Relevance: NCCLs are highly prevalent in daily clinical practices and can impact aesthetics and function, leading to hypersensitivity and impairment of oral-health-related quality of life. Gingival recession is an important clinical indicator for the presence of NCCLs.
Species Recognition of Bitten Leaves Based on Multi-Parameters with BP Neural Network
Authors: Rao Zhimin , Mao Jiandong , Zhao Hu , Zhou Chunyan , Gong Xin
Published: June 2022

There are many species of leaves in nature. The complete leaves are easy for identification, while bitten leaves hinder the recognition of leaf species. In order to accurately recognize the species of injured and damaged leaves, firstly, a recognition system GUI (Graphical User Interface) was designed, then a cameras of iPhone 12 Pro Max was used to collect complete and insect-bitten leaves pictures, obtain the color characteristics and shape characteristics of the leaves by image processing technology, and then combine neural network recognition algorithms to recognize the type of broken leaf with the insect bite. Results in this experiment show that this method can quickly and effectively recognize the species of bitten leaves, and provide an efficient and accurate recognition method for injured and damaged plant.
A super robust and efficient DNA storage architecture based on modulation encoding and decoding
Authors: Zan Xiangzhen , Xie Ranze , Yao Xiangyu , Xu Peng , Liu Wenbin
Published: June 2022

Thanks to its high density and long durability, synthetic DNA has been widely considered as a promising solution to the data explosion problem. However, due to the large amount of random base insertion-deletion-substitution (IDSs) errors from sequencing, reliable data recovery remains a critical challenge, which hinders its large-scale application. Here, we propose a modulation-based DNA storage architecture. Experiments on simulation and real datasets demonstrate that it has two distinct advantages. First, modulation encoding provides a simple way to ensure the encoded DNA sequences comply with biological sequence constraints (i.e., GC balanced and no homopolymers); Second, modulation decoding is highly efficient and extremely robust for the detection of insertions and deletions, which can correct up to ~ 40% errors. These two advantages pave the way for future high-throughput and low-cost techniques, and will kickstart the actualization of a viable, large-scale system for DNA data storage.
Study on machine learning of molar incisor hypomineralization in an endemic fluorosis region in central China
Authors: Zhang Yimeng , Wang Yu , Lu Yang , Zhang Zhaoxin , Wang Yuqi , Jia Jie
Published: June 2022

Objectives The aim of the present study was to develop machine learning model to predict the risk for MIH and identify associated factors in an endemic fluorosis region in central China.Materials and methods A cross-sectional study was conducted with selected regions of 1568 schoolchildren. The clinical examination included the investigation of MIH based on the European Academy of Paediatric Dentistry (EAPD) criteria. In this study, supervised machine learning (e.g., Logistic Regression) and correlation analysis (e.g., Pearson correlation analysis) were used for classification and prediction. Results Overall prevalence of MIH was 13.7%. The nomograph showed that non-dental fluorosis (DF) had great influence on the early occurrence of MIH that was decreased with the strengthen of DF severity. Then, we examined the association between MIH and DF and found DF had a protective correlation with MIH, and the effect of protection became more obvious with the increasing severity of DF. Furthermore, children whose enamel was defective were more prone to experience caries, meanwhile, dental caries was positively correlated with MIH (OR=1.843; 95% CI:1.260 -2.694). However, Exposure to poor quality shallow underground water, as well as gender and oral hygiene, did not increase the likelihood of developing MIH. Conclusions DF should be considered a protective factor within the multifactorial etiology of MIH.Clinical relevance In this study, the correlation between various factors, especially fluorosis, and MIH was explored, and a machine learning model was constructed to make it possible to predict the incidence of MIH. Our study may contribute to the early intervention and clinical planning towards the population with MIH.
CBFDR- Context-Based Fake News Detection and Reporting using Blockchain and Machine Learning
Authors: Mishra Himani , Jain Amita , Tayal Ankur
Published: June 2022

Cases of fake news are increasing at a high pace, especially through social media portals. Even though there are various fact checker websites and portals that distinguish news from real or fake news and ongoing research have been done to stop the propagation of fake news. , The major setback is timely detection, prevention and reporting of fake news. The proposed model CBFDR (Context-Based Fake News Detection and Reporting) first analyzes the domain of the given news through Amazon web services (AWS) Comprehend, secondly detects the fake news through RNN-LSTM (Recurrent neural network – Long short term memory & XG-Boost algorithm (extreme gradient) and thirdly includes a set of domain-experts who analyze the set of fake news as well as report in Block-chain (using smart contract and proposed algorithm Proof of Evidence (PoE)) to stop the propagation of fake news at an early stage. The given paper has shown the highest success rate of 98% using RNN-LSTM and 93% using the XG-Boost algorithm for fake news detection. This paper covers detection, prevention and reporting in one application with an average 60-70% faster and more accurate than the existing models.
The effects of taurine supplementation on obesity and browning of white adipose tissue in high-fat diet-fed mice.
Authors: Bagci Gokhan , Okten Hatice
Published: June 2022

Background: In recent years, a new type of adipose tissue (beige adipose tissue) has been mentioned, unlike white adipose tissue (WAT) and brown adipose tissue (BAT). Beige cells are capable of thermogenesis like BAT. In response to various agents, beige cells can develop within WAT through a process called “browning”. Therefore, the prevention of obesity and related diseases by providing WAT browning with new potential agents has been extensively studied in recent years. Taurine has many physiological functions in the body and has beneficial effects on obesity and related metabolic disorders. For this reason, we aimed to investigate whether taurine supplementation has effects on browning of WAT and attenuating obesity.Methods: Thirty-two male C57BL/6 mice were used for the study. Mice were divided into 4 groups as control, control + taurine, high fat diet (HFD) and HFD + taurine, and fed for 20 weeks. Taurine was given in drinking water (5%). Epididymal WAT samples were obtained from mice and RNA was extracted from these tissues. Expression levels of FLCN, mTOR, TFE3, PGC-1α, PGC1-1β, AMPK, S6K and UCP1 genes were measured by real-time PCR.Results: Taurine supplementation reduced HFD-induced obesity. No UCP1 expression was detected in any of the groups studied. Any of the gene expressions were not significantly different between HFD and HFD + taurine groups. Reduced PGC-1α and PGC-1β expressions were observed in both HFD and HFD + taurine groups.Conclusions: Taurine reduced the obesity in HFD fed mice, but had no effect on browning of epididymal WAT in this study.
Length Weight Relationship of five marine fishes associated with trawler bycatch with record of maximum total length from Eastern Indian Ocean
Authors: Karuppasamy K. , B Sureandiran , Jawahar P. , Tamilselvan R. , Venkataramani V.K.
Published: June 2022

Length-Weight Relationship (LWR) parameters were analyzed for five marine fish species associated with commercial trawler as bycatch from the Tamil Nadu coast, Eastern Indian Ocean: Rhynchostracion nasus, Scolopsis xenochrous, Stethojulis albovittata, Triacanthus nieuhofii and Engyprosopon grandisquama belonging to the five families viz., Ostraciidae, Nemipteridae, Labridae, Triacanthidae and Bothidae. Fishes were sampled monthly between August 2019 to March 2020 from the landings of trawlers operated along the coast of Tuticorin, Chinnamuttom and Colachel, Tamil Nadu coast, with a cod-end mesh size of 35 mm operated at the depth of 20-80 m. Values of the parameter b ranged from 2.734 for Stethojulies albovittata to 3.3300 for Rhynchostracion nasus and a values varied from 0.004115 Rhynchostracion nasus, 0.00809 Scoliopsis xenochrous respectively. All LWRs were significant with r2 values ranged from 0.80441 to 0.9912. In addition, this study provides the information on LWRs and also recorded a new maximum total length for Rhynchostracion nasus, Triacanthus nieuhofii and Engyprosopon grandisquama.
Anti-cancer effect of hUC-MSC-derived exosome-mediated delivery of PMO-miR-146b-5p in colorectal cancer
Authors: Yu siming , Liao ran , Bai lu , Guo madi , Zhang yu , Zhang yumin , Yang qi , Song yushuai , Li zhiwei , Meng qingwei , Wang shubin , Huang xiaoyi
Published: June 2022

BackgroundAntisense oligonucleotide (ASO) is a novel therapeutic platform for targeted cancer therapy. Colorectal cancer (CRC) is the third leading cause of cancer mortality and the prognosis of CRC is poor when hepatic metastasis occurs. We have demonstrated that miR-146b-5p plays an important role in CRC progression. Knocking down miR-146b-5p by an ASO is expected to slow down the progression. However, a safe and effective strategy for delivery of an ASO to its targeted RNA remains as a major hurdle in translational advances.ResultsHuman umbilical cord mesenchymal cell (hUC-MSC)-derived exosomes were used as vehicles to deliver an anti-miR-146b-5p ASO (PMO-146b) to CRC cells. PMO-146b was assembled onto the surface of exosomes(e) through a covalently conjugated anchor peptide CP05(P) that recognized an exosomal surface marker, CD63, forming a complex named ePPMO-146b. The conjugate (ePPMO-146b) was taken up by SW620 cells and effectively inhibited cellular proliferation and epithelial-to-mesenchymal transition. It also exerted antitumor efficacy in a xenograft mouse model of colon cancer by systematic administration, where PPMO-146b was enriched in tumor tissue. Of particular importance was selective distribution of ePPMO-146b in liver compared to native exosomes through in vivo imaging, indicating its therapeutic potential to inhibit hepatic metastasis of CRC.ConclusionOur study highlights the potential of hUC-MSC-derived exosomes anchored with PPMO-146b as a novel safe and effective approach for ASO delivery.
Extracellular epimorphin impairs expression and processing of profilaggrin in HaCaT keratinocytes
Authors: Hori Haruna , Kotani Ayaka , Abe Junya , Matsuguchi Shuji , Hirai Yohei
Published: June 2022

The expression and processing of filaggrin, a filament-associated protein in the skin epidermis, is closely associated with keratinocyte cornification. The large precursor profilaggrin (Pro-FLG) is initially detected at the granular layer in keratohyalin granules, subsequently processed into ten to twelve filaggrin monomers (mFLGs) for keratin assembly, and ultimately degraded into smaller peptides that behave as natural moisturizing factor (NMF) at the outermost epidermis. We previously reported that a t-SNARE protein epimorphin (EPM) often translocates across the membrane upon external stimuli and severely perturbs epidermal terminal differentiation. Using HaCaT keratinocytes with inducible expression and recombinant EPM and FLG, we investigated the effect of extracellular EPM on the expression profile of filaggrin. In response to ectopic stimulation with extracellular EPM, Pro-FLG expression decreased with elimination of keratohyalin granules in the cells, with filaggrin mRNA remained constant and profilaggrin processing was not accelerated. Additionally, using a recombinant form of mFLG engineered for intracellular localization, we found that extracellular EPM hindered proteolytic cleavage of mFLG for production of NMF. Taken together, extracellularly extruded EPM, an epidermal cornification blocker, not only decreases Pro-FLG expression but also reduces the production of NMF in HaCaT keratinocytes.
Peripheral and posterior pole retinal changes in highly myopic Chaoshan Chinese children and adolescents Retinal changes in Chinese children and adolescents
Authors: Zhang Wenli , Chen Shirong , Shi Tingkun
Published: June 2022

Purpose: To determine the prevalence and factors associated with peripheral and posterior pole retinal changes in highly myopic Chinese children and adolescents.Methods: A prospective, consecutive case series and cross-sectional study was designed. One-hundred-and-twenty subjects with high myopia were recruited and underwent cycloplegic refraction, dilated fundus examination, and optical coherence tomography. Statistical analysis was performed to evaluate the factors associated with the development of peripheral and posterior pole retinal changes.Results: The mean spherical equivalent refraction of the subjects was - 8.74 ± 2.86 D, and the mean age of the subjects was 11.45 ± 3.02 years. The most common peripheral retinal changes were snowflake retinal degeneration (27.5%), white without pressure (27.5%), snail-track degeneration (15.00%), and lattice degeneration (15.00%). The most common posterior changes were optic nerve crescent (78.3%) and posterior staphyloma (11.7%). Subjects with peripheral retinal changes had significantly older age and higher myopia compared with subjects without peripheral retinal changes (12.08 ± 3.08 vs. 10.71±2.79 years, -9.26 ± 3.25 vs. -8.13 ± 2.19 D, respectively, both p < 0.05). The presence of optic nerve crescent was associated with thinner choroidal thickness and a higher degree of refractive error (183.35 ± 62.1 µm vs. 219.69 ± 66.82 µm, -9.00 ± 3.08 vs. -7.81 ± 1.55 D, respectively, both p < 0.05).Conclusion: A substantial proportion of the subjects were found to have peripheral and posterior retinal changes. There is an increased risk of retinal changes in eyes with a higher degree of myopia, longer axial length, and thinner choroidal thickness in individuals aged 7–16 years.
EEUCWFL: Energy Efficient Unequal Clustering
With Multi-Input Multi-Output Fuzzy Logic
Authors: PANDEY SHIVENDRA KUMAR , SINGH BUDDHA
Published: June 2022

The Wireless Sensor Network (WSN) consists a group of sensors and a Base Station (BS) or sink. Sensors gather data from the sensing area and send these data to BS, either directly or through multi-hop data transmission. There are several methods of efficient data transmission. Clustering is one of them. WSN uses the many different algorithms for making the cluster to transmit the data from the physical environment to the BS. Clustering

makes the WSN Network efficient and improves the network lifetime. Other data transmission methods like direct transmission consumes very much energy so the life span of the sensor nodes becomes low in comparison to the clustering algorithm. The disadvantage of multi-hop data transmission of clustering algorithm is that a cluster head closer to sink has to forward the data of its own cluster as well as the data of near by clusters. So the node near base station dies sooner. This problem is known as hot-spot problem. The solution of hot-spot problem is unequal clustering. Nodes near base station should be smaller in size to balance the remaining energy of the nodes. In this paper, we have proposed a clustering algorithm (EEUCWFL) which uses multi-input multi-output fuzzy logic to select an optimal cluster head with unequal cluster size. We compared our proposed algorithm with three best known algorithms LEACH, EEUC and CHEF. The Results show that our proposed algorithm optimize energy consumption and improves the network lifetime.
PREDICTINGFINAL STATURE AND BIOLOGICAL PARAMETERS FOR SCHOOL CHILDREN OF JESSORE DISTRICT IN BANGLADESH
Authors:   PhD Fellow, Department of Statistics, University of Rajshahi, Rajshahi 6205 and Assistant Professor, Jessore Shikkha Board Govt. Model School and College, Jessore, Bangladesh., Ali Nawaz Md. Shahjada , Abu Shahin Md. ,   Lecturer, Agrani School & College, RUET, RUET Campus,Rajshahi 6204., Abdul Khalek Md. ,   Professor, Department of Statistics, University of Rajshahi, Rajshahi 6205., Ayub Ali Md. ,   Professor, Department of Statistics, University of Rajshahi, Rajshahi 6205.
Published: June 2022

Objective:The purpose of the present study was to predict the final stature and biological parameters for the school children from Jessore district in Bangladesh. Study Design: The primary data on stature collected from 89 subjects longitudinally,using two-stage sampling strategy. Place and Duration of Study:This study was placed on Jessore district in Bangladesh and duration from November 2006 to November 2018. Material and Method:Bootstrap resampling method was used for addressing the population estimate. The software IBM SPSS 26 was used to estimate the parameters of the BTT growth model. Results: For Bangladeshi boys, the adolescent phase was started from the age 10.77 years with stature 136.87 cm and velocity 4.04 cm/year and attended the peak velocity 6.05 cm/year with stature 152.76 cm at the age 13.96 year and the growth process will be resulted with the final stature 171.33 cm at the age 25 years. For girls, the adolescent phase was started from the age 11.48 years with stature 141.93 cm and velocity 3.83 cm/year and attended the peak velocity 3.90 cm/year with stature 147.64 cm at the age 13.94 year and the growth process will be resulted with the final stature 158.20 cm at the age 25 years. The Age of takeoff in children growing at higher rate than American but lower than European and British for boys but for girls, it was higher rate. Conclusion:These results can be used to treatment and observing the childs growth in Bangladesh as well as in the world.
VERTEBRAL HYDATIDOSIS: UNUSUAL CAUSE OF MEDULLARY COMPRESSION
Authors:   Department of Radiology, Ibn Sina Hospital, Mohammed V University, Rabat, Morocco., Ayadi Chirihan , Amsiguine Najwa ,   Department of Radiology, Ibn Sina Hospital, Mohammed V University, Rabat, Morocco., Naggar Amine ,   Department of Radiology, Ibn Sina Hospital, Mohammed V University, Rabat, Morocco., Elouali Ibtissame ,   Department of Radiology, Ibn Sina Hospital, Mohammed V University, Rabat, Morocco., Benelhousni Khadija ,   Department of Radiology, Ibn Sina Hospital, Mohammed V University, Rabat, Morocco., Moatassim Billah Nabil ,   Department of Radiology, Ibn Sina Hospital, Mohammed V University, Rabat, Morocco., Nassar Ittimade ,   Department of Radiology, Ibn Sina Hospital, Mohammed V University, Rabat, Morocco.
Published: June 2022

We present a case of a 30-year-old woman, without any notable pathological history, admitted with a slow spinal cord compression. The spinal MRI showed an extensive cystic lesion from D8 to D11 compressing the spinal cord with signs of myelopathy, costal and paraspinal soft tissues invasion, compatible with vertebral hydatidosis. The surgical procedure was a decompression by laminectomy and incomplete cystectomy with osteosynthesis. histological analysis confirmed the diagnosis of vertebral hydatidosis. vertebral location remains rare, but severe, of delayed diagnosis due to the absence of specific clinical signs, it is evoked by radiology and confirmed by histological analysis. Its prognosis remains poor with frequent recurrences. The optimal treatment is the prevention of the disease.
ANALYSIS AND DESIGN OF MULTI-STOREYED (G+2) RESIDENTIAL BUILDING
Authors:   Assistant professor, Civil Department, Velammal College of Engineering and Technology, Madurai, Tamilnadu, India., Deepan Chakaravarthi A.V. , Dhivya E. ,   Bachelor of Engineering Student, Velammal College of Engineering and Technology, Madurai, Tamilnadu, India., Gracia Angel Rajakumari L. ,   Bachelor of Engineering Student, Velammal College of Engineering and Technology, Madurai, Tamilnadu, India., Hashini D. ,   Bachelor of Engineering Student, Velammal College of Engineering and Technology, Madurai, Tamilnadu, India.
Published: June 2022

Structural design is an investigation method of the rigidity, strength and stability of the building. The essential aim in structural analysis and design is to construct a structure capable of overcoming all applied loads without failure during its intended life. This project attempts to understand the structural behavior of various components in the multi-storied building. planning, analysis, designing of multi-storied building has been taken up for residential building (G+2). Thereby depending on the suitability of plan, layout of beams and positions of columns are fixed. Dead loads are calculated based on material properties and live loads are considered according to the code IS875-part 2, footings are designed based on safe bearing capacity of soil. For the design of columns and beams analysis is done by limit state method to know the moments they are acted upon. Slab designing is done depending upon the type of slab (one way or two way), end conditions and the loading. From the slabs the loads are transferred to the beams, thereafter the loads from the beams are taken up by the columns and then to footing finally the section is checked for the components manually and using STAAD Pro V8i software for the analysis of structure, maximum shear force, maximum bending moment are computed.
THE EFFECT OF CAPITAL STRUCTURE AND PROFITABILITY ON THE VALUE OF THE COMPANY HEALTH SUB-SECTOR ON THE INDONESIA STOCK EXCHANGE
Authors:   Lecture University of Borobudur, Jakarta, Indonesia., Meida Arief Elsya , Maretha Della ,   Lecture University of Borobudur, Jakarta, Indonesia., N.D Alivia ,   Student Economics Faculty University of Borobudur, Jakarta, Indonesia., Kamil Muslim ,   Lecture University of Borobudur, Jakarta, Indonesia.
Published: June 2022

This study aims to analyze how the influence of capital structure and profitability on the value of companies in sub-Sector Health Companies on the Indonesia Stock Exchange. The sample consists of 8 companies listed on the Indonesia Stock Exchange for the period 2010-2020. The data used in this study is capital structure data represented by Debt to Asset Ratio and Debt to Equity Ratio, profitability data represented by Return On Asset Ratio, all of which areindependent variabels. While the value of the company is represented by Price to Book Value as a dependent variable. This study uses secondary data in the form of financial statements of sample companies and sample determination using purposive sampling techniques. Data analysis uses classical assumption tests and multiple linear regressions. Based on the results of the statistical test, the Debt to Asset Ratio variable has a negative and significant relationship with price to book value. And Debt to Equity Ratio and Return On Asset have a positive and significant relationship with Price to Book Value. Simultaneously variable Debt to Asset Ratio, Debt to Equity Ratio and Return On Asset have a positive and significant effect on price to book value. The relationshipshows that together the higher the Debt to Asset Ratio, Debt to Equity Ratio and Return On Asset the higher the Price To Book Value reflected by the higher investor confidence in the company.
COMPLETE ANDROGEN INSENSITIVITY SYNDROME : A CASE REPPORT AND REVIEW OF LITERATURE
Authors:   Department of Obstetrics Gynecology CHU Med VI Marrakech., K. Dorkami , S. Bahi ,   Department of Obstetrics Gynecology CHU Med VI Marrakech., H. Asmouki ,   Department of Obstetrics Gynecology CHU Med VI Marrakech., B. Fakhir ,   Department of Obstetrics Gynecology CHU Med VI Marrakech., A. Bassir ,   Department of Obstetrics Gynecology CHU Med VI Marrakech., A. Aboulfalah ,   Department of Obstetrics Gynecology CHU Med VI Marrakech., A. Soummani ,   Department of Obstetrics Gynecology CHU Med VI Marrakech.
Published: June 2022

Complete androgen insensitivity syndrome or testicular feminization syndrome is the most common form of male pseudohermaphrodism, caused by a failure of androgen receptor binding. Patient with male genotype 46 XY, has a female morphotype with well developed external sexual organs. We report the case of two young patients aged 23 and 21 with a TF syndrome discovered during the exploration of primary amenorrhea. A bilateral orchiectomy was performed with institution of estrogen-progestogen hormone treatment.
EVALUATION OF VARIOUS PROGNOSTIC FACTORS FOR DIABETIC FOOT IN COVID 19 PANDEMIC: A CLINICAL STUDY
Authors: Agarwal Pushpendra , Omar Shivam , Bajpayi Madhurya
Published: June 2022

Background: Diabetes mellitus is a well-known metabolic disorder of varying severity, especially involving carbohydrate metabolism. It is present in 2-3% of the general population, which may be higher (4-5%) in populations above 40 years of age. Aims and Objectives: (1) To study the clinical presentation of diabetic foot infection, (2) to study the various factors having causal relation with diabetic foot infection, (3) to study various modalities available for treatment of diabetic foot infection, (4) to correlate these factors and management strategies with prognosis of diabetic foot infection. Materials and Methods: A prospective study was carried out in patients of diabetes mellitus Type II presenting with foot infection. This study was carried out in the Department of Surgery in collaboration with Department of Medicine, Maharani LaxmiBai Medical College Jhansi U.P. from January 2020 to June 2021 over the period of 18 months. Result: In our study of 300 Type II diabetes patients who attended medical and surgical Out Patient Departments (OPD) in M.L.B m Medical College Jhansi from January, 1st 2020 to June 30st 2021 over a period of 16 months. A total of 50 patients were found to have a variety of diabetic foot infection. Conclusion: Totally 50 patients of diabetic foot infection were studied in patients from Jhansi and the surrounding areas for a period of 18 months from January, 1st 2020 to June 30st 2021. In our study, the incidence of diabetic foot infection in patients with Type II diabetes was found to be 16.64%.
REMOTE LEARNING DURING COVID 19 PANDEMICAND ITS IMPACT ON EFL LEARNERS: AN ANALYSIS
Authors:   Assistant Professor Department of English Language, King Khalid University Abha KSA., Sagir Khan Aayesha , Alnmer Samar ,   Head of English Language Department, King Khalid University Abha KSA., Ahmed Khan Sagir ,   Associate Professor Department of Computer Science, I K College DAVV India.
Published: June 2022

The problem with a coronavirus posed a challenge to the education system, forcing educators to change to a wholly E-learning environment. Many educational institutions were unprepared for such a fast transformation. During the COVID-19 shutdown, distant study of foreign languages caused current teaching technologies to increase the breadth of the educational process, broaden its practical direction, and contribute to the intensity of students autonomous work, boosting their cognitive activity.The articles goals include: defining the types and specifics of modern edTech for the educational process as it transitions from no E-Learning to fully E-Learning and eliminating the role of the Internet as a means of information and communication edTech in teaching foreign languages at higher education establishments is to discover how to improve students learning at higher education institutions, the significance of employing remote edTechs, and the SWOC (Strengths, Weaknesses, Opportunities, and Challenges) examination of E-learning strategies during the pandemic shutdown. This studys contribution is to analyse learners new experiences in online education and to examine the viability of virtual ways of learning. This is accomplished by analysing the replies of 228 students to a survey-based questionnaire. The studys validity was tested using a descriptive statistical approach. The key issues that influence and effect online EFL learning during COVID-19 are technological, academic, and communication concerns. According to the survey findings, most EFL learners are dissatisfied with continued online learning since they have not made the desired gain in language learning performance.
FAUX ANEVRYSME DE L ARTERE UTERINE : ETIOLOGIE INHABITUELLE DES HEMORRAGIES DU POST-PARTUM
Authors:   Service de Gynecologie-Obstetrique, CHU Mohammed VI, Marrakech, Maroc., Kabine M. ,   Universite Cadi Ayyad, Marrakech, Maroc., Chraibi-Kaadoud H. ,   Service de Gynecologie-Obstetrique, CHU Mohammed VI, Marrakech, Maroc.,   Universite Cadi Ayyad, Marrakech, Maroc., Bassir A. ,   Service de Gynecologie-Obstetrique, CHU Mohammed VI, Marrakech, Maroc.,   Universite Cadi Ayyad, Marrakech, Maroc., Jalal H. ,   Service de Radiologie, CHU Mohammed VI, Marrakech, Maroc.,   Universite Cadi Ayyad, Marrakech, Maroc., Asmouki H. ,   Service de Gynecologie-Obstetrique, CHU Mohammed VI, Marrakech, Maroc.,   Universite Cadi Ayyad, Marrakech, Maroc., Aboulfalah A. ,   Service de Gynecologie-Obstetrique, CHU Mohammed VI, Marrakech, Maroc.,   Universite Cadi Ayyad, Marrakech, Maroc., Soummani A. ,   Service de Gynecologie-Obstetrique, CHU Mohammed VI, Marrakech, Maroc.,   Universite Cadi Ayyad, Marrakech, Maroc.
Published: June 2022

Le faux anevrysme de lartere uterine est une complication rare, encore mal connue de la cesarienne, il est responsable dune hemorragie du post-partum secondaire, le plus souvent severe. Nous rapportons une observation dun faux anevrysme de lartere uterine gauche survenu 1 mois apres accouchement par cesarienne et revele par des metrorragies. Le diagnostic repose sur les donnees echographiques couple au Doppler vasculaire.Langiographie des arteres uterines constitue lexamen de reference. Son rÃƒÂ´le est double, diagnostique et therapeutique par embolisation arterielle selective permettant lexclusion definitive de la lesion, tout en preservant la fertilite des patientes. Summary: The false aneurysm of the uterine artery is a rare, still poorly understood complication of caesarean section, it is an uncommun cause of secondary postpartum hemorrhage, most often severe. We report a case of a false aneurysm of the left uterine artery which occurred 1 month after caesarean delivery, revealed by metrorrhagia. Diagnosis is based on ultrasound data coupled with vascular Doppler. Angiography of the uterine arteries is the reference examination. Its role is twofold: diagnostic and therapeutic by selective arterial embolization allowing the definitive exclusion of the lesion, while preserving the fertility of the patients.
USE OF INFORMATION AND COMMUNICATION TECHNOLOGY IN TEACHING AND LEARNING IN EMERGENCY SITUATIONS: RELEVANCE, CHALLENGES AND ETHICAL CONCERNS
Authors:   Department of Educational Foundations Nnamdi Azikiwe University, Awka., Aloysius Ezeanolue Fr. , Jideofor J. Ezewuzie ,   Department of Educational Foundations Federal College of Education (T) Umunze, Anambra State., Greg Ekeh Fr. ,   Department of Educational Foundations Nnamdi Azikiwe University, Awka.
Published: June 2022

This study sought to ascertain the relevance of the use of information and communication technology (ICT), its challenges and ethical concerns in teaching and learning in in emergency situations. Some instances of such situations are natural disasters and outbreak of diseases. A case in hand about such diseases is the current Corona Virus Pandemic. Using a qualitative method of conceptual frame and critical analysis, the paper explored the meanings and imports of technology, information technology, communication technology and information and communication technology, in reference to teaching and learning in emergency situations. It was discovered that these concepts, though interrelated, are not exactly the same, and that information and communication technology is better understood in the light or backdrop of technology itself. The components of ICT were discussed, leading to the ascertainment of the relevance of and challenges to ICT in teaching and learning in emergency situations, as well as ethical issues emanating from the use of ICT. In the course of the analytical exploration, the roles of stakeholders such as parents, teachers, students and the government were highlighted. Based on the insight gained from the discourse, the paper came to a conclusion that the relevance of the use of ICT in teaching and learning in emergency situations is indisputable, but not without some challenges. Although ethical issues constitute a challenge of its own in the context of ICT, it is believed that their proper understanding and application by various stakeholders, especially teachers and students, will be of immense help in overcoming other challenges facing the use of ICT in teaching and learning. In the light of the conclusion arrived at, the paper recommended, among others, that teachers at all levels of education be well knowledgeable in the use of ICT in teaching and learning, with its ethical concerns, so as to be able to guide students properly, and students endeavor to be discreet in their use of the internet, while government should legislate and provide enabling environments that will make online teaching and learning thrive in emergency situations.
IMPACT OF SEASONAL VARIATION ON FLUORIDE IONS CONCENTRATIONS IN GROUNDWATER IN THE MARADI REGION (CENTRAL NIGER)
Authors:   PhD Student, Faculty of Sciences and Technology, Department of Chemistry, Materials Water and Environment Laboratory, Abdou Moumouni University, BP 10662, Niamey, Niger., Farroukou Moustapha Bello Oumarou , Gourouza Marou ,   Full Professor, Faculty of Sciences and Technology, Department of Chemistry, Materials Water and Environment Laboratory, Abdou Moumouni University, BP 10662, Niamey, Niger., Nazirou Garba Labo Mahaman ,   PhD Student, National Polytechnic Institute, FÃ©lix HouphouÃ«t-Boigny (INP-HP), BP 1093, Yamoussoukro, CÃ´te dIvoire.
Published: June 2022

The present study aims to study the impact of seasonal variation on fluoride ion concentrations in groundwater in the Maradi region. To achieve this goal, two (2) water sampling campaigns were carried out.Sampling was carried out over the entire study area. Water samples were taken from wells and boreholes.The results of this study show that the high levels of fluoride ions are obtained during the rainy season likewise, this content of fluoride ions vary according to the variation of certain ions.