bluuebunny/crossref_metadata_2025 huggingface dataset:
Experimental Assessment of Rebar Corrosion in Concrete Slab Using Ground Penetrating Radar (GPR)
Authors: Zaki Ahmad , Megat Johari Megat Azmi , Wan Hussin Wan Muhd Aminuddin , Jusman Yessi
Published: November 2018

Corrosion of steel reinforcement is a major cause of structural damage that requires repair or replacement. Early detection of steel corrosion can limit the extent of necessary repairs or replacements and costs associated with the rehabilitation works. The ground penetrating radar (GPR) method has been found to be a useful method for evaluating reinforcement corrosion in existing concrete structures. In this paper, GPR was utilized to assess corrosion of steel reinforcement in a concrete slab. A technique for accelerating reinforcement bar corrosion using direct current (DC) power supply with 5% sodium chloride (NaCl) solution was used to induce corrosion to embedded reinforcement bars (rebars) in this concrete slab. A 2 GHz GPR was used to assess the corrosion of the rebars. The analysis of the results of the GPR data obtained shows that corrosion of the rebars could be effectively localized and assessed.
Current Evidence for the Use of Smoflipid® Emulsion in Critical Care Patients for Parenteral Nutrition
Authors: Leguina-Ruzzi Alberto A. , Ortiz Rina
Published: November 2018

There are strong data showing that malnutrition is highly prevalent in intensive care unit patients (20–50% in the worldwide), presenting a negative accumulated body energy balance. This results in an increased mortality, infections, and hospital length stay with high costs associated with the total treatment. Parenteral nutrition is the first option when the patient’s physical condition is not suitable for oral nutrient intake. It is composed essentially by lipids as an energy source, metabolic, and structural function. However, these patients also require a mixture of essential and nonessential fatty acids (SMOF emulsions) to supply not only energy needs but also restore immunological, anti-inflammatory, and proregenerative functions. A revision of the safety and efficacy of Smoflipid® in patients requiring long-term parenteral nutrition was discussed here. Although controversial data are available indicating the contraindications or effectiveness of its use, most of studies presented indicate favorable benefits associated with improved clinical outcomes. The reported roles of this supplementation include positive immunomodulatory and anti-inflammatory effects, positive impact in liver function, reduction of hospital stay, and nosocomial infections as additional contributions to its energetic role, which in many cases results in reduced total costs per patient. Finally, many authors propose that the use of Smoflipid® should become a gold standard of parenteral nutrition in intensive unit care patients and that the costs associated with this supplement should not be limiting for its use, not only to improve the clinical outcome but also to reduce the treatment costs.
Nonlinear Analysis of Flexible Pile near Undrained Clay Slope under Lateral Loading
Authors: Jiang Chong , Li Yu , Liu Lin , Lin Hang
Published: November 2018

In this paper, a method is developed for nonlinear analysis of laterally loaded long‐flexible pile near undrained clay slope. The ideal elastic‐plastic p‐y curve model is used as the basic calculation model to study the pile‐soil interaction system. To consider the slope effect on the soil resistance along with pile length, related reduction function expressions of soil resistance are selected by assessing the existing methods. A finite difference iteration scheme is proposed to solve the pile’s deflection curve equations to obtain nonlinear response of pile. The developed method is validated by comparing its results with the existing method, which shows a good agreement. A number of parameters analyses are carried out, and effects of different influence factors on laterally loaded pile are further discussed.
High Glucose‐Induced ROS Production Stimulates Proliferation of Pancreatic Cancer via Inactivating the JNK Pathway
Authors: Luo Jiao , Xiang Yukai , Xu Xiangxiang , Fang Dazhang , Li Ding , Ni Fubiao , Zhu Xiandong , Chen Bicheng , Zhou Mengtao
Published: November 2018

Aberrant glucose metabolism of diabetes mellitus or hyperglycemia stimulates pancreatic tumorigenesis and progression. Hyperglycemic environment can increase the ROS level of tumors, but the role of upregulation of ROS levels in pancreatic cancer (PC) still remains controversial. Here, the same as other reports, we demonstrate that high glucose promoted pancreatic cancer cell growth and resulted in an increase in the level of ROS. However, it is interesting that the phosphorylation of JNK was reduced. When treating PC cells with N‐acetyl‐L‐cysteine (NAC), the intracellular ROS generation is repressed, but the expression of phosphorylation of JNK and c‐Jun increased. Moreover, the JNK inhibitor SP600125 significantly promoted cell proliferation and suppressed cell apoptosis of pancreatic cancer cells under high glucose conditions. Collectively, high levels of ROS induced by high glucose conditions stimulated the proliferation of pancreatic cancer cells, and it may be achieved by inactivating the JNK pathway.
Comparison of the Fully Automated FilmArray BCID Assay to a 4-Hour Culture Test Coupled to Mass Spectrometry for Day 0 Identification of Microorganisms in Positive Blood Cultures
Authors: Verhoeven Paul O. , Haddar Cyrille H. , Rigaill Josselin , Fonsale Nathalie , Carricajo Anne , Grattard Florence , Pozzetto Bruno
Published: November 2018

Rapid bacterial identification of positive blood culture is important for adapting the antimicrobial therapy in patients with blood stream infection. The aim of this study was to evaluate the performance of the multiplex FilmArray Blood Culture Identification (BCID) assay by comparison to an in-house protocol based on MALDI-TOF MS identification of microcolonies after a 4-hour culture, for identifying on the same day the microorganisms present in positive blood culture bottles. One hundred and fifty-three positive bottles from 123 patients were tested prospectively by the 3 techniques of bacterial identification: 11 bottles yielding negative results by the 3 tests were considered false positive (7.2%). The reference MALDI-TOF MS technique identified 134 monomicrobial (87.6%) and 8 double infections (5.2%), which resulted in a total of 150 microorganisms. Globally, 137 (91.3%) of these 150 pathogens were correctly identified by the fully automated multiplex FilmArray BCID system at the species or genus level on day of growth detection, versus 117 (78.8%) by MALDI-TOF MS identification on nascent microcolonies after a 4-hour culture (P < 0.01). By combining the two approaches, 140 (93.5%) of the positive bottles were identified successfully at day 0. These results confirm the excellent sensitivity of the FilmArray BCID assay, notably in case of multimicrobial infection. Due to the limited number of targets included into the test, it must be coupled to another identification strategy, as that presented in this study relying on MALDI-TOF MS identification of microcolonies obtained after a very short culture period.
Treatment of Chronic Bony Mallet Fingers by Dorsal Extension Block Pinning with Percutaneous Curettage
Authors: Takase Fumiaki , Yamasaki Kyoko , Kokubu Takeshi , Mifune Yutaka , Inui Atsuyuki , Kuroda Ryosuke
Published: November 2018

Dorsal extension block pinning is a commonly performed surgical technique for acute bony mallet fingers. However, the treatment of chronic bony mallet finger remains controversial. We investigated the use of dorsal extension block pinning with percutaneous curettage for chronic bony mallet fingers. Seven patients with chronic bony mallet fingers were treated by dorsal extension block pinning with percutaneous curettage. The average age was 17 (range, 12–23) years, and the average time from injury to surgery was 20 (range, 7–49) weeks. Bone union was achieved in all patients. None of the patients experienced pain after bone union. The average loss of distal interphalangeal joint extension was 6 (range, 5–20) degrees, and the average flexion was 59 (range, 40–80) degrees. The Crawford functional score was excellent in three patients, good in two, and fair in two. Dorsal extension block pinning with percutaneous curettage could be a useful treatment for chronic bony mallet fingers.
Perception among Healthcare Professionals of the Use of Social Media in Translating Research Evidence into Clinical Practice in Mangalore
Authors: Unnikrishnan Bhaskaran , Rathi Priya , Shah Daivik , Tyagi Abhay , Rao Anish V. , Paul Koyel , Tomy Joe
Published: November 2018

Introduction. Social media has a potential to bring about major changes in the healthcare system. Objective. To find out the pattern of use of social media among healthcare professionals (HCPs) and perception, facilitators, and barriers of using social media, to translate evidence into clinical practice. Method. We conducted a cross-sectional study among 196 HCPs of institutions attached to a university using a self-administered questionnaire. Result. 97.3% used social media; however, only 63.4% used it for research. YouTube was the most preferred media. Majority of people believed that social media enables wide range of evidence over the shorter span of time, poses a threat to privacy, and cannot replace face to face interaction. Perceived barriers were the privacy concern, unprofessional behavior, lack of reliability, and information overload. Conclusion. There is a need for the development of appropriate guidelines for sharing the research output among various stakeholders using social media.
Ameliorating Iron Overload in Intestinal Tissue of Adult Male Rats: Quercetin vs Deferoxamine
Authors: El-Sheikh Arwa A. , Ameen Shimaa Hamed , AbdEl-Fatah Samaa Salah
Published: November 2018

Objective. The aim of our study is to compare the role of the new natural alternative (Quercetin) with the current iron-chelation therapy (Deferoxamine (DFO)) in the effect of iron overload on small intestinal tissues and to investigate the possible underlying molecular mechanisms of such toxicity. Methods. Forty-two adult male albino rats were divided into six groups: control groups, DFO, Quercetin, iron overload, iron overload+DFO, and iron overload+Quercetin groups. Animals received daily intraperitoneal injection of Deferoxamine (125 mg /kg), Quercetin (10 mg/kg), and ferric dextran (200 mg/kg) for 2 weeks. Results. Iron overloaded group showed significant increase in serum iron, total iron binding capacity (TIBC), transferrin saturation percentage (TS %) hepcidin (HEPC), serum ferritin, nontransferrin bound iron (NTBI), and small intestinal tissues iron levels. Iron overload significantly increased the serum oxidative stress indicator (MDA) and reduced serum total antioxidant capacity (TAC). On the other hand, iron overload increased IL6 and reduced IL10 in small intestinal tissues reflecting inflammatory condition and increased caspase 3 reactivity indicating apoptosis and increased iNOs expressing cell indicting oxidative stress especially in ileum. In addition, it induced small intestinal tissues pathological alterations. The treatment with Quercetin showed nonsignificant differences as compared to treatment with DFO that chelated the serum and tissue iron and improved the oxidative stress and reduced tissue IL6 and increased IL10 and decreased caspase 3 and iNOs expressing cells in small intestinal tissues. Moreover, it ameliorated the iron overload induced pathological alterations. Conclusion. Our study showed the potential role of Quercetin as iron chelator like DFO in case of iron overload induced small intestinal toxicity in adult rats because of its serum and tissue iron chelation, improvement of serum, and small intestinal oxidative stress, ameliorating iron induced intestinal inflammation, apoptosis, and histopathological alterations.
Strengthening Effect of Prestressed Near‐Surface‐Mounted CFRP Tendon on Reinforced Concrete Beam
Authors: Jung Woo-Tai , Park Jong-Sup , Kang Jae-Yoon , Park Hee Beom
Published: November 2018

Efforts are being made to use FRP (fiber‐reinforced polymer) for reinforcements instead of traditional construction materials like steel owing to its remarkable mechanical properties. Among them, this study developed a CFRP tendon to be used as near‐surface‐mounted reinforcement together with a dedicated prestressing system and investigates experimentally the strengthening effect considering various variables including the amount of reinforcement, the bond performance, and the strength and damage ratio of the concrete. The test results reveal that one line of reinforcement improved the strengthening performance by about 55% and two lines by 96% and that the bonding of the CFRP tendon enhanced the strengthening performance by 15%. Higher strength and damage of the concrete seem to have a poor effect on the overall strengthening performance. However, the use of CFRP tendon with bond performance higher than 11 MPa, filler, and anchorage system appears to promote stable strengthening behavior.
Salivary MicroRNAs for Early Detection of Head and Neck Squamous Cell Carcinoma: A Case-Control Study in the High Altitude Mestizo Ecuadorian Population
Authors: Salazar-Ruales Carolina , Arguello Jessica-Viviana , López-Cortés Andrés , Cabrera-Andrade Alejandro , García-Cárdenas Jennyfer M. , Guevara-Ramírez Patricia , Peralta Patricio , Leone Paola E. , Paz-y-Miño César
Published: November 2018

Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer with the highest incidence worldwide. HNSCC is often diagnosed at advanced stages, incurring significant high mortality and morbidity. The use of saliva, as a noninvasive tool for the diagnosis of cancer, has recently increased. Salivary microRNAs (miRNAs) have emerged as a promising molecular tool for early diagnosis of HNSCC. The aim was to identify the differential expression of salivary miRNAs associated with HNSCC in the high altitude mestizo Ecuadorian population. Using PCR Arrays, miR-122-5p, miR-92a-3p, miR-124-3p, miR-205-5p, and miR-146a-5p were found as the most representative ones. Subsequently, miRNAs expression was confirmed in saliva samples from 108 cases and 108 controls. miR-122-5p, miR-92a-3p, miR-124-3p, and miR-146a-5p showed significant statistical difference between cases and controls with areas under the curve (AUC) of 0.73 (p < 0.001), 0.70 (p < 0.001), 0.71 (p = 0.002), and 0.66 (p = 0.008), respectively. miRNAs were also deregulated in between HNSCC localizations. A differentiated expression of miR-122-5p between oral cancer and oropharynx cancer (AUC of 0.96 p = 0.01) was found: miR-124-3p between larynx and pharynx (AUC = 0.97, p < 0.01) and miR-146a-5p between larynx, oropharynx, and oral cavity (AUC = 0.96, p = 0.01). Moreover, miR-122-5p, miR-124-3p, miR-205-5p, and miR-146a-5p could differentiate between HPV+ and HPV- (p=0.004). Finally, the expression profiles of the five miRNAs were evaluated to discriminate HNSCC patient’s tumor stages (TNM 2-4). miR-122-5p differentiates TNM 2 and 3 (p = 0.002, AUC = 0.92), miR-124-3p TNM 2, 3, and 4 (p < 0.001, AUC = 98), miR-146a-5p TNM 2 and 3 (p < 0.001, AUC = 0.97), and miR-92a-3p TNM 3 (p < 0.001, AUC = 0.99). Taken together, these findings show that altered expression of miRNAs could be used as biomarkers for HNSCC diagnosis in the high altitude mestizo Ecuadorian population.
Pseudoaneurysm of the Perforating Peroneal Artery following Ankle Arthroscopy
Authors: Tonogai Ichiro , Fujimoto Eiki , Sairyo Koichi
Published: November 2018

The use of standard anterolateral and anteromedial portals in ankle arthroscopy results in reduced risk of vascular complications. Anatomical variations of the arterial network of the foot and ankle might render the vessels more susceptible to injury during procedures involving the anterior ankle joint. The literature, to our knowledge, reports only one case of a pseudoaneurysm involving the peroneal artery after ankle arthroscopy. Here, we report the unusual case of a 48-year-old man in general good health with the absence of the anterior tibial artery and posterior tibial artery. The patient presented with a pseudoaneurysm of the perforating peroneal artery following ankle arthroscopy for traumatic osteoarthritis associated with nonunion of the medial malleolus. The perforating peroneal artery injury was repaired by performing end-to-end anastomosis. The perforating peroneal artery is at higher risk for iatrogenic injury during ankle arthroscopy in the presence of abnormal arterial variations of the foot and ankle, particularly the absence of the anterior tibial artery and posterior tibial artery. Before ankle arthroscopy, surgeons should therefore carefully observe the course of the perforating peroneal artery on enhanced 3-dimensional computed tomography, especially in patients with a history of trauma to the ankle joint.
Potassium Iodide for Cutaneous Inflammatory Disorders: A Monocentric, Retrospective Study
Authors: Anzengruber Florian , Mergenthaler Caroline , Murer Carla , Dummer Reinhard
Published: November 2018

Objectives: Potassium iodide (KI) is a medication that has been used for decades in dermatology and it is mentioned as a treatment option in all major dermatology textbooks. Yet, there is little recent information on its efficacy. In our study, we wanted to retrospectively evaluate the therapy response to KI in our patients. Methods: The hospital information system was searched for patients treated with KI at the Department of Dermatology (University Hospital Zurich) in the last 20 years (January 1, 1998 to December 31, 2017). A total of 52 patients were found and, subsequently, 35 patients were included in our study. Results: KI was prescribed for the following skin conditions: erythema nodosum, disseminated granuloma anulare, necrobiosis lipoidica, nodular vasculitis, cutaneous sarcoidosis, and granulomatous perioral dermatitis/ rosacea. The median duration of KI intake was 5 ± 7.7 weeks (range 1–26). The global assessment of efficacy by the treating physician showed an improvement of disease in about a third of all patients. No response was seen in 14 patients and 9 even had a progression of disease. An adverse event was documented in 16 cases. Conclusions: Our findings show that an improvement was reached in only about a third of all cases. High response rates with only mild side effects (in 16 out of 35 patients) were observed.
Impact of Assisted Peritoneal Dialysis Modality on Outcomes: A Cohort Study of the French Language Peritoneal Dialysis Registry
Authors: Guilloteau Solène , Lobbedez Thierry , Guillouët Sonia , Verger Christian , Ficheux Maxence , Lanot Antoine , Béchade Clémence
Published: November 2018

Background: Patients on peritoneal dialysis (PD) can be assisted by a nurse or a family member and treated either by automated PD (APD) or continuous ambulatory PD (CAPD). The aim of this study was to evaluate the effect of PD modality and type of assistance on the risk of transfer to haemodialysis (HD) and on the peritonitis risk in assisted PD patients. Method: This was a retrospective study based on data from the French Language PD Registry. All adults starting assisted PD in France between 2006 and 2015 were included. Events of interest were transfer to HD, peritonitis and death. Cox regression models were used for statistical analysis. Results: Among the 12,144 incident patients who started PD in France during the study period, 6,167 were assisted. There were 5,060 nurse-assisted and 1,095 family-assisted PD patients. Overall, 5,171 were treated by CAPD and 996 by APD. In multivariate analysis, CAPD, compared to APD, was not associated with the risk of transfer to HD (cause specific hazard ratios [cs-HR] 0.96 [95% CI 0.84–1.09]). Patients on nurse-assisted PD had a lower risk of transfer to HD than family assisted PD patients (cs-HR 0.85 [95% CI 0.75–0.97]). Neither PD modality nor type of assistance were associated with peritonitis risk. Conclusions: In assisted PD, technique survival was not associated with PD modality. Nurse-assisted patients had a lower risk of transfer to HD than family assisted patients. Peritonitis risk was not influenced either by PD modality, or by type of assistance. Both APD and CAPD should be offered to assisted-PD patients.
The Use of an Arginine-Enriched Oral Nutrition Supplement to Enhance Wound Healing from a Cesarean Section
Authors: Hicks-Roof Kristen
Published: November 2018

Background: Surgical wounds can directly hinder daily activities and leave scars that can have long-term impacts on a patient. Cesarean sections account for over one-third of all baby deliveries, resulting in women faced with a wound needing rapid healing to take care of their baby. Case Presentation: The patient received an arginine-enriched oral nutrition supplement twice daily for 14 days as a therapeutic intervention to aid in wound healing and recovery. At the 2-week postpartum visit, validated scar assessment scales were completed to determine how the surgical wound was healing. It was shown that this therapeutic intervention improved wound healing as indicated by low scar assessments. Conclusion: This woman showed that consuming an arginine-enriched oral nutrition supplement could optimize healing following a cesarean section. Future research needs to be conducted on a larger sample size to determine whether these results can be generalized to the broader population.
Development of Inflammatory Immune Response-Related Drugs Based on G Protein-Coupled Receptor Kinase 2
Authors: Han Chenchen , Li Yifan , Wang Yang , Cui Dongqian , Luo Tingting , Zhang Yuwen , Ma Yang , Wei Wei 
Published: November 2018

G protein-coupled receptor kinase 2 (GRK2), as a vital Ser/Thr kinase, is an important regulatory protein in the inflammatory immune response (IIR) by maintaining the balance between the function of inflammatory immune cells and non-conventional inflammatory immune cells and regulating inflammatory immune cell infiltration, inflammatory cytokine secretion, and the signaling associated with endothelial function. However, the imbalance of GRK2 expression and activity plays an important role in the development of IIR-related diseases, such as hypertension, heart failure, Alzheimer’s disease, type 2 diabetes mellitus, insulin resistance, rheumatoid arthritis, thyroid cancer, multiple sclerosis, and liver cancer. Small molecule GRK2 inhibitors, including balanol, Takeda inhibitors, paroxetine and derivatives, M119 and gallein, peptides, RNA aptamers, Raf kinase inhibitory protein, and microRNAs, that can directly inhibit GRK2 kinase activity have been identified by different strategies. This review discusses recent progress in one of the hallmark molecular abnormalities of GRK2 in IIR-related diseases and explores the soft regulation of IIR by innovative drugs reducing the excessive activity of GRK2 to basal levels, without damaging normal physiological function, to ameliorate inflammatory disorders.
miR-2954 Inhibits PI3K Signaling and Induces Autophagy and Apoptosis in Myocardium Selenium Deficiency
Authors: Liu Qi , Cai Jingzeng , Gao Yunan , Yang Jie , Gong Yafan , Zhang Ziwei 
Published: November 2018

Background/Aims: Selenium (Se) deficiency can lead to several cardiac diseases, including Keshan disease in humans, mulberry heart disease in pigs and cardiac injury in chickens. MicroRNAs have been a research focus in recent years and have been shown to participate in a new avenue of cell death-autophagy, which can play a significant role in several types of heart disease. Methods: MicroRNAome analysis showed that the expression of miR-2954 was increased in the myocardium of selenium-deficient chickens, and PI3K was predicted to be the target gene. The target relationship between miR-2954 and PI3K was verified with a double fluorescence enzyme assay and RNA Protein Interaction Prediction and molecular docking software. qRT-PCR and western blotting were used to detect the expression of PI3K and related pathway components in selenium-deficient chickens and miR-2954 knockout/overexpression cardiomyocytes. Results: In this study, we observed that miR-2954 overexpression led to inhibition of PI3K pathway in vivo and in vitroled to inhibition of the PI3K pathway in vivo and in vitro. Conclusion: The expression of miR-2954 was increased in selenium-deficient myocardium, whereas overexpression of miR-2954 led to autophagy and apoptosis of myocardial cells during cardiac injury through regulation of the PI3K pathway; whether this phenomenon is a self-protection mechanism of the organism or damage caused by miR-2954 requires further study. Our findings provides new insight apoptosis in cardiomyocytes; additionally, we aim to provide a new direction for the diagnosis and targeted treatment of myocardial diseases.
MicroRNA Quantitation During Dendritic Cell Endocytosis Using Imaging Flow Cytometry: Key Factors and Requirements
Authors: Tong Qiang , Zhu Ying , Zhang Dandan , Cai Qing , Qu Wenchun , Cooper Christopher D. O. , Wang Jiaqi , McHugh Patrick C.
Published: November 2018

Background/Aims: MicroRNA (miRNA)-induced suppression of dendritic cells (DCs) has been implicated in many diseases. Therefore, accurate monitoring of miRNA endocytosis by DCs is important for understanding the role of miRNAs in many diseases. Recently, a method for measuring the co-localization of Argonaute 2 (AGO2)-associated miRNAs on laser-scanning confocal microscopy method was proposed to localize the miRNAs. But its definition was limited by the number of observed cells through its accuracy. Methods: In this study, a method based on imaging flow cytometry was developed to localize miR-590-5p with fluorescent probes in DCs. miR-590-5p proven to play an important role in tumor immunity. This method enabled the quantification, visualization and localization of the fluorescence intensity in 30,000 individual cells. Results: Using this method, the DCs with different endocytotic ability were distinguished. The behaviour of miR-590-5p during endocytosis under the stimulation of tumor antigen in DCs was observed, binding to its cognate target mRNA and degradation in DCs. Conclusion: This method based on imaging flow cytometry provide an additional method to study miRNA processing in DCs, which makes it a valuable addition to existing miRNA research techniques.
The Work That Maps Do
Authors: Withers Charles W. J.
Published: November 2018

Martin Brückner’s The Social Life of Maps will appeal to scholars from many disciplines—material studies and English literature (his home fields), geography, American studies, and, not least, the U.S. historical community. Maps have never been the preserve of geographers, certainly not in their making nor, as Brückner convincingly shows, in the various practices of public and popular “mappery.” One of the strengths of this book is that it re-affirms and deepens the connections of geography as an educational and imaginative practice with the power of the historical imagination in shaping America’s national identity, territorial reach, and, if only nascent in the period that Brückner considers, empire.
Thoracic scent efferent system of the Tessaratomidae sensu lato (Hemiptera: Heteroptera: Pentatomoidea) with implication to the phylogeny of the family
Authors: KMENT PETR , VILÍMOVÁ JITKA
Published: November 2018

We studied the cuticular structures associated with the opening of the adult metathoracic scent glands in the family Tessaratomidae. The terminology previously used for these structures in the Tessaratomidae and Pentatomoidea is briefly reviewed and most suitable terms are selected (i.e., metathoracic scent apparatus, internal and external scent efferent system, internal orifice, vestibule, ostiole, ostiolar groove, peritreme, auricle, spout, groove, ruga, disc, peritremal lobes, evaporatorium, mycoid surface, mushroom body, bridge, alveole, trabeculae, and peritremal surface). We examined and illustrated external scent efferent system of 40 species from 33 genera belonging to all three subfamilies of Tessaratomidae sensu lato, i.e. Tessaratominae, Natalicolinae, and Oncomerinae. Three basic types were recognized: i) Oncomerinae – ostiole slightly removed laterally from the position between coxal acetabula, oval, ostiolar groove not developed or very short, peritreme in form of spout attached anterolaterally to the ostiole; ii) Tessaratomidae sensu stricto (= Tessaratominae + Natalicolinae) – ostiole situated between acetabula, strongly incised mesad, thus vestibule distally opened in two planes (ventrally and laterally) as ostiolar groove, peritreme in form of anterior and posterior peritremal lobes surrounding the ostiolar groove; and iii) Platytatina (Platytatus ambiguus Bergroth, 1892) – ostiole shifted near to lateral metapleural margin, ostiolar groove reduced, situated between two flat, reniform processes (median and lateral lobe). A polarity of these structures is suggested: the type i) of Oncomerinae is regarded as plesiomorphic(shared with Urostylididae, Dinidoridae, etc.); the type iii) of Platytatina is homologized with type ii) of Tessaratominae sensu stricto; the type ii) is unique within Pentatomoidea and considered as an autapomorphy. The information content of the characters of the external scent efferent system and metathoracic spiracle for a phylogenetic hypothesis of relationships within Pentatomoidea is tested by cladistic analyses. We found some apomorphies helping to define Tessaratomidae and Plataspidae, most of the characters, however, seem to be homoplasious at family level. The results of the cladistic analyses further support the monophyly of Dinidoridae + Tessaratomidae sensu lato and that of Tessaratomidae sensu stricto, while the relationships of Oncomerinae and Tessaratomidae sensu stricto as well as the relationships among the family-group taxa within Tessaratomidae sensu stricto need further studies.
Life stage descriptions, taxonomic notes, and new records for the mayfly family Leptohyphidae (Ephemeroptera)
Authors: BAUMGARDNER DAVID E. , BURIAN STEVEN K. , BASS DAVID
Published: November 2018

The larval stages of Tricorythodes fictus Traver, T. cobbi Alba-Tercedor and Flannagan, and T. mosegus Alba-Tercedor and Flannagan are described for the first time based upon reared specimens. The rarely reported Asioplax dolani (Allen) is newly documented from the Austroriparian ecological region of Texas. Leptohyphes zalope Traver, known from the southwestern United States and much of Central America, is newly documented from the Caribbean Islands of Grenada and Tobago. This represents only the second leptohyphid mayfly known from both Continental America and the Caribbean region. Additional Caribbean records of Allenhyphes flinti (Allen) are also given.
Virgil, Aeneid 11, Pallas and Camilla, 1–224, 498–521, 532–596, 648–689, 725–835
Authors: Gildenhard Ingo , Henderson John
Published: November 2018

A dead boy (Pallas) and the death of a girl (Camilla) loom over the opening and the closing part of the eleventh book of the Aeneid. Following the savage slaughter in Aeneid 10, the book opens in a mournful mood as the warring parties revisit yesterday’s killing fields to attend to their dead. One casualty in particular commands attention: Aeneas’ protégé Pallas, killed and despoiled by Turnus in the previous book. His death plunges his father Evander and his surrogate father Aeneas into heart-rending despair – and helps set up the foundational act of sacrificial brutality that caps the poem, when Aeneas seeks to avenge Pallas by slaying Turnus in wrathful fury. Turnus’ departure from the living is prefigured by that of his ally Camilla, a maiden schooled in the martial arts, who sets the mold for warrior princesses such as Xena and Wonder Woman. In the final third of Aeneid 11, she wreaks havoc not just on the battlefield but on gender stereotypes and the conventions of the epic genre, before she too succumbs to a premature death. In the portions of the book selected for discussion here, Virgil offers some of his most emotive (and disturbing) meditations on the tragic nature of human existence – but also knows how to lighten the mood with a bit of drag.

This course book offers the original Latin text, vocabulary aids, study questions, and an extensive commentary. Designed to stretch and stimulate readers, Ingo Gildenhard’s volume will be of particular interest to students of Latin studying for A-Level or on undergraduate courses. It extends beyond detailed linguistic analysis to encourage critical engagement with Virgil’s poetry and the most recent scholarly thought.

King's College, Cambridge, has generously contributed to this publication.
Ideal Cardiovascular Health Status and Risk of Cardiovascular Disease or All-Cause Mortality in Chinese Middle-Aged Population
Authors: Dong Ying , Hao Guang , Wang Zengwu , Wang Xin , Chen Zuo , Zhang Linfeng
Published: November 2018

We estimated the prevalence of ideal cardiovascular health (CVH), and its relationship with cardiovascular disease (CVD) and all-cause mortality in a Chinese population. A cross-sectional survey of CVD risk factors was conducted among Chinese participants aged 35 to 64 years in 2009 to 2010. In 2017, 8965 participants completed follow-up assessments in which CVD and all-cause mortality were collected; 8754 participants were eligible for analysis. The percentage of meeting all 7 ideal CVH metrics was 0.10%. During a median follow-up of 6.3 years, the incidence of CVD and all-cause mortality were 6.02% and 4.85% per 1000 person-year in participants with 0 to 1 ideal CVH metrics, 3.33% and 3.57% in those with 2 to 5, 0.40% and 0.79% in those with 6 to 7, respectively. After adjusting for covariates, the risk of CVD was significantly lower in participants with 2 to 5 (hazard ratio [HR]: 0.67, 95% confidence interval [CI]: 0.45-0.98) and 6 to 7 (HR: 0.12, 95%CI: 0.02-0.87) ideal CVH metrics compared to those with 0 to 1 ideal CVH metrics. The risk of all-cause mortality was decreased as ideal CVH metrics increased (HR: 0.78, 95%CI: 0.70-0.88). A greater number of ideal CVH metrics was associated with a lower risk of CVD and all-cause mortality, but the prevalence of all 7 ideal CVH metrics was low in a Chinese population.
Displaced Dental Materials in the Maxillary Sinus: An Original Series. Analysis and Definition of a Surgical Decision-Making Process
Authors: Brescia Giuseppe , Fusetti Stefano , Apolloni Federico , Marioni Gino , Saia Giorgia
Published: November 2018

Objectives:

Displacement of dental materials into the maxillary sinus occurs in daily dental practice; dental implants have become a new common foreign body (FB), as implantation has become routine. The main goal of the present study was to analyze an original series of patients consecutively treated for maxillary sinus FBs. A secondary goal was to propose a decision-making flowchart on the basis of the authors’ experience and a critical analysis of literature to select the most appropriate surgical approach.

Methods:

Eleven consecutive patients evaluated for maxillary sinus FBs consisting of dental material were considered.

Results:

For removal of the FBs, a nasal endoscopic approach was preferred in 5 cases, a nasal combined approach in 2 cases, an oronasal combined approach in 2 cases, and a lateral window approach in 2 cases. In 2 of 11 cases, complications were reported. A decision-making flowchart to select the best surgical approach is reported.

Conclusions:

The correct choice and application of FB removal techniques allow minimization of unfavorable outcomes and creation of an appropriate environment for new dental treatment. Prospective, large series-based studies will be necessary to confirm the safety and clinical efficacy of the proposed decision-making flowchart.
Associations Between Patient-Reported Outcome Measures of Asthma Control and Psychosocial Symptoms
Authors: Lee ChangWon C. , Holder-Niles Faye F. , Haynes Linda , Chan Yuen Jenny , Rea Corinna J. , Conroy Kathleen , Cox Joanne E. , Bottino Clement J.
Published: November 2018

There is growing emphasis on using patient-reported outcome measures to enhance clinical practice. This study was a retrospective review of scores on the Childhood Asthma Control Test (C-ACT) and the Pediatric Symptom Checklist-17 (PSC-17) at a pediatric primary care center in Boston, Massachusetts. A total of 218 patients were selected at random using billing codes for well-child (WC) care and asthma, excluding complex medical conditions. Cutoff scores were used to identify uncontrolled asthma (C-ACT ⩽19) and clinically significant psychosocial symptoms (+PSC-17). Multiple logistic regression was used to measure associations between C-ACT ⩽19 and +PSC-17, adjusting for covariates. In multivariable analysis, C-ACT ⩽19 at WC visits was associated with +PSC-17 at WC visits (adjusted odds ratio = 3.2 [95% confidence interval = 1.3-8.6]). C-ACT ⩽19 at non-WC visits was also associated with +PSC-17 at WC visits (adjusted odds ratio = 3.1 [95% confidence interval = 1.2-8.9]). Patient-reported outcome measures of asthma control and psychosocial symptoms were positively correlated in this sample.
Models of paediatric learning for UK primary care clinicians: An unmet need
Authors: Snelson Edward , Hoskin Julie
Published: November 2018

Objectives:

Despite a long-standing declaration of educational need in the area of paediatrics in primary care, there is little in the way of strategy for delivering high-quality learning relevant to the specific needs of the primary care team. This article seeks to explore various models for delivering primary care centred paediatric education to inform discussion about how to meet this need.

Methods:

As well as considering various educational modalities, we share the lessons learned from setting up a novel educational model for practitioners working in a primary care setting. We consider the importance of education for those working where they may be operating from a position of uncertainty, which may lead to unnecessary referrals or unsafe practice. We explore the complexities of the interface which occurs between primary and secondary care in designing and delivering education.

Results:

There are various barriers to the setting up of a programme of education designed specifically for primary care, including time needed, funding and uncertainty of success. While the needs of the whole primary care team needs to be considered, there is a growing number of advanced clinical practitioners and physician associates who are likely to engage with paediatric-specific professional development opportunities, at least as much as the traditional medical workforce.

Conclusion:

The lack of adequate paediatric education for those working in primary care poses a risk which should not be ignored. In the absence of a coherent strategy in the United Kingdom to identify and meet the learning needs of practicing primary care clinicians, one possible solution is for health regions to develop bespoke initiatives based on an understanding of the local workforce, their learning needs and the local resources available. We explore the various modalities through which this can be achieved and share the lessons learned from the development of a multifaceted programme of paediatric learning for primary care clinicians.
The Impact of Dust and Sandstorms in Increasing Drought Areas in Nineveh Province, North-western Iraq
Authors: Yahya Bashar Muneer , Seker Dursun Zafer
Published: November 2018

According to many local and international reports, the risk of dust and sandstorms has increased significantly in Iraq, creating serious environmental and social problems. In this study Nineveh province was selected as the study area to investigate the relationship between the increase in such storms and drought expansion. In the study, storm-feeding regions and a probable storm path were detected using remote sensing and Geographic Information System (GIS). Standardized Precipitation Index (SPI) and runoff values were estimated and gathered as supplementary data with rainfall, temperature and storm frequency, where all the data were standardized to make them statistically comparable. Temporal variations analysis and Spearman’s rank correlation techniques were applied to summarize the strength relationships between the storm frequency and the entire dataset. Unusual behaviours were noticed and represented by decreasing runoff values and drought conditions fluctuating between moderate to extreme, where these behaviours were accompanied by an abnormal increase in storm frequency. Reasonable negative relationships equalled - 0.78 for rainfall and - 0.61 for runoff, while positive rank correlations equalled + 0.45 for temperature and + 0.16 for SPI. These results indicate a positive relationship between the storm frequency and increased drought areas, where 2.2% of the territory turned to drought and desert areas during the studied period between 1992 and 2017.
Voids in fiber-reinforced polymer composites: A review on their formation, characteristics, and effects on mechanical performance
Authors: Mehdikhani Mahoor , Gorbatikh Larissa , Verpoest Ignaas , Lomov Stepan V
Published: November 2018

Voids, the most studied type of manufacturing defects, form very often in processing of fiber-reinforced composites. Due to their considerable influence on physical and thermomechanical properties of composites, they have been extensively studied, with the focus on three research tracks: void formation, characteristics, and mechanical effects. Investigation of voids in composites started around half a century ago and is still an active research field in composites community. This is because of remaining unknowns and uncertainties about voids as well as difficulties in their suppression in modern manufacturing techniques like out-of-autoclave curing and parts with high complexity, further complicated by increased viscosity of modified resins. Finally, this is because of the increasing interest in realization of more accurate void rejection limits that would tolerate some voidage. The current study reviews the research on formation, characterization, and mechanical effects of voids, which has been conducted over the past five decades. Investigation and control of void formation, using experimental and modeling approaches, in liquid composite molding as well as in prepreg composite processing are surveyed. Techniques for void characterization with their advantages and disadvantages are described. Finally, the effect of voids on a broad range of mechanical properties, including inter-laminar shear, tensile, compressive, and flexural strength as well as fracture toughness and fatigue life, is appraised. Both experimental and simulation approaches and results, concerning voids' effects, are reviewed.
National Identity, Implicit In-Group Evaluation, and Psychological Well-Being Among Emirati Women
Authors: Grey Ian , Thomas Justin
Published: November 2018

A sense of connectedness, and belonging to a valued social group (social identity processes), has been found to promote psychological well-being. This study, using implicit and explicit assessments, extends the exploration of social identity and well-being to citizens of the United Arab Emirates (Emiratis). In this cross-sectional correlational study, Emirati college women ( N = 210), all of them bilingual (English/Arabic), performed an affective priming task designed to assess, implicitly, in-group (Emirati) preference (a positive bias toward the in-group relative to an out-group). Participants also completed the Multicomponent In-Group Identification Scale (MIIS), a measure of in-group identification and self-report measures of English/Arabic language proficiency. Participants also reported their psychological well-being using the World Health Organization’s well-being index. Implicit in-group preference and self-reported Arabic language dominance were independently predictive of higher levels of psychological well-being. The implicit measure was the strongest, most robust, predictor. Interventions aimed at maintaining or increasing a positive sense of a shared social identity may be a useful objective of public mental health strategy.
Physical Performance and Fall Risk in Persons With Traumatic Brain Injury
Authors: Klima Dennis , Morgan Lindsay , Baylor Michelle , Reilly Cordia , Gladmon Daniel , Davey Adam
Published: November 2018

Injuries sustained from traumatic brain injury (TBI) culminate in both cognitive and neuromuscular deficits. Patients often progress to higher functioning on the Rancho continuum even while mobility deficits persist. Although prior studies have examined physical performance among persons with chronic symptoms of TBI, less is known about the relatively acute phase of TBI as patients prepare for rehabilitation discharge. The aims of this cross-sectional study were to (a) compare balance and gait performance in 20 ambulant persons with moderate to severe TBI who were nearing rehabilitation discharge with their age-matched controls and (b) describe performance with thresholds for fall risk and community navigation. During a designed task circuit, 40 participants (20 persons with TBI and 20 controls) performed the Timed Up and Go (TUG), gait velocity, and Walking and Remembering tests. Balance testing included the Fullerton Advanced Balance Scale (FABS) and instrumented Modified Clinical Test for Sensory Interaction in Balance (MCTSIB). Statistical analyses included analysis of covariance for group comparisons and a multivariate analysis of covariance for MCTSIB sway velocities with anthropometric controls. The TBI group (mean [ M] age = 42, standard deviation [ SD] =19.5 years; 70% males) performed significantly more poorly on all mobility tests ( p < .05) and their scores reflected a potential fall risk. Gait velocity was significantly slower for the TBI versus control group ( M = .96, SD = 2.6 vs. M = 1.5, SD = 2.2 m/s; p < .001), including TUG times ( M = 13.5, SD = 4.9 vs. M = 7.7, SD = 1.4; p < .001). TBI participants also demonstrated significantly greater sway velocity on all MCTSIB conditions ( p < .01) and lower performance on the FABS ( p < .001). Performance indices indicate potential fall risk and community navigation compromise for individuals with moderate to severe TBI. Physical performance scores support the need for continued interventions to optimize functional mobility upon discharge.
The Last Bastion of Rehabilitation: Contextualizing Youth Correctionalism in Canada
Authors: Adorjan Michael , Ricciardelli Rose
Published: November 2018

This article draws on research conducted with Canadian provincial correctional officers who have experience with youth in closed-custodial settings since the enactment of the 2003 Youth Criminal Justice Act. In Canada, where attempts to avoid a full embrace of the punitive turn seem to be persistent, we examine youth justice as the “last bastion” of the rehabilitative ideal as mediated by youth correctional officers. Our findings reveal that while officers retain a clear commitment to the ideal of rehabilitation and a desire to “save” young people, they are increasingly under siege by the changing context of prison, shifting managerial priorities, and the paradox of trying to help convicted youth in an inherently punitive environment.