bluuebunny/crossref_metadata_2025 huggingface dataset:
Weed Management in Apple
Authors: Dittmar Peter J. , Williamson Jeffrey G.
Published: May 2022

This fact sheet is part of the Weed Management Guide that been updated with new recommendations. Written by Peter J. Dittmar and Jeffrey G. Williamson, and published December 2011. Reviewed October 2014.
HS88/WG014: Weed Management in Pome Fruit (Apple and Pear) (ufl.edu)
Nociones de economía monetaria. Una mirara minimalista a Venezuela y Ecuador
Authors: Cordero Yoskira
Published: May 2022

Esta investigación presenta un análisis del efecto de las políticas públicas sobre el sector económico. Su temática aborda postulados que ofrecen una mirada desde Latinoamérica hacia el mundo, desde el trueque y las monedas sociales hasta bitcoin y las monedas virtuales. En un mundo cambiante, y con cambios cada vez más acelerados, este libro visualiza los grandes desafíos y oportunidades que enfrentarán Venezuela y Ecuador en el contexto global. Entre otras cosas, el libro ofrece respuestas a la pregunta de si estamos preparados para un mundo totalmente conectado, y cuáles son las implicaciones económicas, sociales y políticas de una economía global.
I Feel Robbed: Students’ Responses to Traumatic Disruptions of Internship Placements Secondary to COVID-19
Authors: Toth Chelsea , LaBarre Heather , Murray Gillian
Published: May 2022

Internship placements were disrupted by COVID-19, resulting in an abrupt transition from in-person to remote work. In response, academic institutions developed virtual assignments to assist students in obtaining required internship hours. This study examined the influence of COVID-19 on social work students enrolled in institutions of higher education participating in field internships. A mixed-methods exploratory study was utilized to understand the experience and impact of the pandemic on students’ emotional, physical, and mental well-being. The majority of students reported negative impacts on their mental health. Students also reported being denied the opportunity for professional closure within internship placements, specifically with supervisors, staff, and clients. The results identify mental health and coping skills, along with professional preparedness as common themes. The findings regarding the impact on mental health align with national data collected by the Council on Social Work Education (CSWE).
ANALISIS BIAYA PERSONAL PENDIDIKAN SISWA SEKOLAH DASAR KABUPATEN DONGGALA
Authors: Gagaramusu Yusdin , Firmansyah Arif , . Nashrullah , . Sisriawan
Published: May 2022

Penelitian ini merupakan analisis biaya personal pendidikan yang dikeluarkan oleh orang tua siswa Sekolah Dasar di Kabupaten Donggala. Penelitian ini bertujuan untuk 1) mengidentifikasi jenis biaya personal pendidikan siswa SD Kabupaten Donggala; 2) menganalisis perbandingan biaya personal pendidikan antar kecamatan; 3) menganalisis peluang pembiayaan pendidikan di SD Kabupaten Donggala bersumber dari Pemerintah Daerah. Penelitan ini dilakukan dengan menggunakan metode penelitian kombinasi dengan teknik pengumpulan data berupa survei, wawancara, observasi, dan studi dokumen. Sampel penelitian siswa SD di 5 Kecamatan Tanantovea, Labuan, Banawa, Rio Pakava dan Sojol diambil secara purposive random sampling. Hasil penelitian menunjukkan bahwa 1) Umumnya di 5 Kecamatan, jenis biaya pesonal pendidikan siswa SD yang dikeluarkan oleh orang tua meliputi pembelian buku dan alat tulis, tas sekolah dan sejenisnya, pakaian seragam, sepatu, uang jajan dan biaya transport; 2) umumnya di 5 Kecamatan, biaya personal pendidikan lebih besar dari biaya operasi per siswa di setiap satuan pendidikan dan 3) beberapa rekomendasi pembiayaan pendidikan yang dapat direkomendasikan dapat dialokasikan oleh Pemerintah Daerah untuk mengurangi biaya personal pendidikan seperti penyediaan alat transportasi seperti bus sekolah, program makanan tambahan serta bantuan sosial pendidikan bagi siswa yang kurang mampu di Kabupaten Donggala.
Manfaat Pembelajaran Eksplorasi, Elaborasi, Dan Konfirmasi Pada Tanggung Jawab Guru
Authors: Sari Siti Mayang , Mahlia Yamnur , Sari Winning Amintas Kartika Waruwu , Jalaluddin Jalaluddin
Published: May 2022

Setiap guru memiliki tanggung jawab untuk melakukan kegiatan mengeksplorasi, mengelaborasi, dan mengkonfirmasi saat mengadakan proses belajar mengajar dengan menggunakan gadget sebagai perangkat tambahan pembelajaran e-learning yang dilakukan pada proses belajar. Namun terkadang sebagian guru kurang bertanggung jawab dalam pembelajarannya dengan menggunakan kurikulum yang berlaku. Tanpa disadari seorang guru saat mengajar harus dapat mengaplikasikan ketiga komponen kegiatan belajar tersebut. Pentingnya pelatihan serta sosialisasi tentang kegiatan pembelajaran yang menggunakan tiga komponen kegiatan tersebut. Penelitian ini menggunakan metode penelitian kualitatif deskriptif yaitu mengkaji literatur jurnal terdahulu dengan mendeskripsikan hasil penelitian yang berkaitan dengan penulisan ini. Tujuan penulisan ini untuk mendapatkan hasil yang maksimal menurut penelitian terdahulu tentang bagaimana tanggung jawab guru dalam proses pembelajaran dengan menggunakan tiga komponen diatas. Sehingga akan mendapatkan sebuah kesimpulan yang signifikan terhadap kegiatan eksplorasi, elaborasi, dan konfirmasi dapat dilakukan dengan bimbingan serta tanggung jawab dari guru melalui bimbingan dan pelatihan guru.
Penerapan Model Pembelajaran Kooperatif Tipe Number Head Together (Nht) Untuk Meningkatkan Prestasi Belajar Siswa
Authors: Sahono Bambang , Insanistyo Bayu , Agustina Emi
Published: May 2022

Penelitian ini bertujuan untuk mendeskrIPAikan penerapan model pembelajaran kooperatif tipe number head together (NHT) untuk meningkatkan prestasi belajar IPA siswa kelas V SD Negeri 47 Kota Bengkulu. Rancangan penelitian ini menggunakan penelitian tindakan kelas model Kemmis dan McTaggart. Subyek penelitian adalah siswa kelas V Sekolah Dasar Negeri 47 di Kota Bengkulu yang berjumlah 32 orang, terdiri atas 13 orang laki-laki dan 19 orang perempuan. Teknik pengumpulan data menggunakan lembar penilaian dan tes, sedangkan teknik analisis data dengan rata-rata (mean) dan presentase. Hasil penelitian menunjukkan bahwa penerapan model pembelajaran kooperatif tipe NHT dapat meningkatkan prestasi belajar IPA siswa kelas V di Sekolah Dasar Negeri 47 Kota Bengkulu. Implikasi hasil penelitian ini adalah jika guru-guru ingin meningkatkan prestasi belajar siswa pada mata pelajaran IPA, maka dapat menggunakan model pembelajaran kooperatif tipe NHT.
BANKING RISK MANAGEMENT AND RESUMPTION MEASURES IN THE FACE OF STRONG EXTERNAL CHALLENGES
Authors:   University of Customs and Finance, Zarutska Olena , Novikova Ludmila ,   University of Customs and Finance
Published: May 2022

The article considers the current trends in the country's banking system, which take place in difficult conditions of external shocks associated with the military aggression of the Russian Federation in Ukraine, and as a consequence of falling GDP, outflow of labor and capital abroad, and the rupture of economic relations. Currently, the country's banking system withstands the impact, ensures payments, provides customers with a sufficient amount of cash hryvnia, performs all its functions. In extremely harsh conditions, banks maintain their financial stability and maintain solvency. In such circumstances, the NBU's procedures for improving risk management systems, developing crisis response measures and restoring banks play an important role. In particular, the Resolution “On Approval of the Regulations on Resumption Plans of Banks of Ukraine and Banking Groups” adopted by the NBU in 2019 deserves considerable attention. The Regulations is designed to ensure the financial stability of banks and their groups, to minimize the main risks of their activities and possible losses that may arise due to the implementation of negative factors in the banking system of Ukraine. The main purpose of this normative document is to introduce in banks and banking groups such a planning process that would allow to effectively restore activities to restore financial stability, in case of implementation of negative scenarios or deterioration of financial condition. Banks take into account their own size, complexity, volume and types of operations and services, organizational structure, risk profile, features of activities when developing a resumption plan. In addition, such a plan should be consistent and integrated with the bank's strategy, business plan, corporate governance system, risk management, capital and liquidity planning measures, business and financing continuity plan in crisis conditions. Each bank has developed an effective system of indicators in order to identify the impact of negative factors in a timely manner. Such a system should take into account all the individual characteristics of the bank, including the business model. Due to the regulatory requirements of the NBU, banks had the opportunity to test measures to resume operations long before the implementation of real external shocks.
MONETARY POLICY OF THE NBU: TRENDS AND CHANGES IN THE MONEY SUPPLY
Authors:   University of Customs and Finance, Shchetynin Anatolii
Published: May 2022

From the point of view of real and in the last two years, mainly negative in their consequences, changes in our social production, the main directions of the monetary policy developed and implemented by the National Bank of Ukraine are considered. Measures taken by the central bank to implement monetary policy are analyzed in connection with the government's actions to stimulate economic development and overcome the negative consequences that arose during the pandemic and significant changes in the global market conditions. Attention is focused on the analysis of the steps taken by the main regulator in order to counter the rapid inflationary process, which especially intensified in 2021 and the threat of significant rates of which remains in the current year. The factors that led to significant changes in the national currency, manifested in a significant weakening of its purchasing power, were identified. Among them, some attention is paid to the analysis of the impact of the pandemic on the economy of Ukraine. The fact of slow and insufficient response of the government to the current situation in the country is stated. The named external factor was also strengthened by the political factor, which found its expression in the insufficiently high level of professionalism of a significant part of high-ranking state officials who came to power on the wave of pre-election populism. At the same time, both external and internal factors that had a significant impact on price growth in Ukraine were considered. It is stated that the anti-inflationary actions of the central bank can be successful only with the restructuring of the domestic economy. Some attention is paid to the actions of the government, which are associated with intentions to strengthen the investment process and which are largely implemented through the banking system. The main factors of the weakening of the hryvnia exchange rate against the US dollar are revealed and possible directions for strengthening the national currency are identified. Analyzed the main activities of the central bank to address the current problems of the domestic banking system.
ECONOMIC AND MATHEMATICAL TOOLS FOR PREDICTING THE CURRENCY EXCHANGE RATE
Authors:   National University of Ostroh Academy, Melnyk Ostap , Novoseletskyy Oleksandr ,   National University of Ostroh Academy
Published: May 2022

The article deals with the analysis of existing approaches to exchange rate forecasting. It also includes the review of Ukrainian and foreign scientists on this topic. The authors of this article have considered the main disadvantages and benefits of existing forecasting dimensions, as well as individual methods and models. They indicated ways to facilitate the implementation of currency exchange rate forecasting using neural networks with software libraries for various programming languages and individual software applications, as well. As a result, the authors have systematized knowledge about existing approaches used in the process of currency exchange rate forecasting. There are two dimensions of currency exchange rate forecasting, in particular, intuitive and formalized ones. The intuitive dimension is peculiar to short-term forecasting and is often used in trading. Its main advantages include the ability to consider structural changes in the economy that can significantly affect the exchange rate formation itself and the speed of forecasting. However, the disadvantage of intuitive methods is the inability to prove formally the quality of the obtained forecasts. The advantages of the formalized dimension of forecasting include the ability to prove the quality. Businesses and government agencies use it the most often. Extrapolation methods and machine learning methods are mainly used to predict the exchange rate using formalized methods. Moreover, the reviewed studies indicate that among the well-known extrapolation methods for predicting the exchange rate, autoregressive models (VAR, AR, ARMA, ARIMA, SARIMA, ARCH, GARCH, ARDL) and smoothing methods (floating averages, adaptive methods and models) are used the most frequently. Machine learning methods include neural networks. Trend models have proved to be ineffective for currency exchange rate forecasting. The reason for this appeared to be using large amounts of data for currency exchange rate forecasting, and each fluctuation there directly affects the whole phenomenon.
DIGITAL ECONOMY: ESSENCE, CHARACTERISTICS AND TASKS OF MANAGEMENT
Authors:   Lviv State University of Internal Affairs, Zhivko Zinaida , Rodchenko Svitlana ,   O.M. Beketov Kharkiv National University of Municipal Economy, Lelyuk Nataliia ,   O.M. Beketov Kharkiv National University of Municipal Economy
Published: May 2022

The aim is to study the essence of "digital economy" concept, highlight its characteristics and develop measures to manage it. To achieve this goal, existing approaches to the concept of "digital economy" have been studied; impact of digitalization on the state, businesses and individuals have been considered; measures to manage the development of digital economy have been developed. The following methods of scientific research have been used while writing the article: scientific abstraction, generalization, analysis and synthesis, analytical. The existing approaches to understanding the essence of "digital economy" concept have been generalized. It has been established that there are the following approaches to understanding the concept of "digital economy": structural-sectoral process, communication, practical, evolutionary. The following features of digital economy have been identified: digitalization, virtualization, molecularization, network structure, and lack of intermediaries, convergence of computerization, communication lines and services, innovation, consumer involvement in production, consumer interaction, globalization and inconsistency. The advantages of digitalization, which are manifested at three levels: state, business entities and individuals, have been analyzed, identified and formulated. The rating of Ukraine for the last five years according to the World Digital Competitiveness Index has been analyzed. Management measures aimed at the development of digital economy should include the creation of favorable environment for the dissemination of digital innovation and development; bridging the digital divide between different industries; regulation of labor relations in digital economy; updating educational programs in higher education institutions in accordance with the requirements of digital economy; stimulating competition in digital economy; support for interaction and exchange of experience between states in digital transformation of society. Practical application of proposed theoretical and applied approaches will accelerate the process of economy digitalization and increase the positive impact on economic system.
El Bitcoin lightning network y el portafolio diversificado de cryptos en las Wallet: México – Alemania, casos de uso.
Authors:   Universidad de Guadalajara, Álvarez Ascencio Esmeralda , Reinders Matthias ,   CEO de masdemas, Alemania.
Published: May 2022

El lightning y la creciente diversificación del portafolio de las criptomonedas en una o más Wallet son temas internacionales que deben analizarse desde diferentes naciones. Se ha hablado y escrito mucho de estos temas, sin embargo, se percibe que aún se transmite la información en lenguajes muy técnicos que crea limitantes con los usuarios o inversionistas principiantes. El presente documento se enfoca principalmente al Bitcoin, sin embargo, no se detendrá a estudiar el origen, significado, funcionamiento o características de las criptomonedas en general; pues como se mencionó en líneas anteriores, actualmente existe bastante información de ellas. En este estudio, se considera importante conocer a grandes rasgos, la postura jurídica – financiera que existe entre México y Alemania en relación a las criptomonedas, el primero de ellos considerado como un país subdesarrollado y el segundo, considerado un país desarrollado, dos visiones de diferentes continentes. Una vez realizado esto, se analizará el impacto que ha tenido el Bitcoin lightning network y la diversificación del portafolio de cryptos en una o más Wallet, así como algunos casos de uso de Bitcoin.
Habilidades del aprendizaje autónomo que emplean los estudiantes en entornos virtuales de enseñanza y aprendizaje (EVEA) durante la pandemia COVID-19
Authors: Sánchez González Carmen Lilia , Moreno Méndez Willebaldo
Published: May 2022

Como resultado de la pandemia COVID-19, la educación se trasladó de un modelo presencial a uno virtual prácticamente de forma obligada. Súbitamente estudiantes y maestros se vieron interactuando en un entorno virtual de enseñanza y aprendizaje (EVEA), para lo cual no todos estaban preparados. Los EVEA exigen un mayor compromiso del estudiante respecto a sus habilidades cognitivas y metacognitivas para acceder a un mejor nivel de aprendizaje. Ante ello, el aprendizaje autónomo, y las habilidades que requiere, se erige como una de las principales estrategias para que los estudiantes puedan gestionar su aprendizaje de forma eficaz. Con el objetivo de identificar tipo y nivel de posesión de habilidades de aprendizaje autónomo que aplican estudiantes universitaritos, se realizó un estudio descriptivo y prolectivo de corte cuantitativo en 530 estudiantes de la carrera de Cirujano Dentista, de la Facultad de Estudios Superiores Zaragoza, UNAM (en lo sucesivo FES Zaragoza). Se aplicó un instrumento para identificar las habilidades del aprendizaje autónomo agrupadas en cinco categorías de análisis. Principales resultados por tipo de habilidad: 1. Cognitivas: buscar y organizar información, 86%; saber problematizar, 69%. 2. Afectivas e interactivas: establecer relaciones duraderas, 92%; autocontrol de los impulsos, 61%. 3. Motivacionales: gusto por estudiar a distancia, 92%; integración proceso de aprendizaje-proyecto de vida, 60%. 4. Metacognitivas: compromiso para lograr metas de aprendizaje, 91%; identificar condiciones de riesgo para el estudio, 66%. 5. De autorregulación: manejo adecuado de los tiempos de estudio en EVEA, 95%; preparar materiales para estudiar en línea, 63%.
PENGARUH INDENPENDENSI DAN PROFESIONALISME AUDITOR TERHADAP KINERJA AUDITOR GUNA MEMPERTAHANKAN KUALITAS AUDIT
Authors: Mukoffi Ahmad , Perawati Yosepha Cristina , Wibisono Sukarno Himawan
Published: May 2022

This study aims to determine how the influence of independent variables and auditor professionalism on auditor performance. The type of data that has been used in this study was quantitative data with 60 samples of public accounting firms in East Java. The population in this study were 150 auditors using the purposive random sampling method obtained using a good questionnaire to be analyzed using SPSS version 26. The results of this study indicate that the independent variable and professionalism The independent variable shows a t-count value of 6.459 with a significance of 0.025 0.05, and the professionalism variable has a value of 3,460 with a significance of 0.000 which shows the effect on auditor performance. The auditor has a significant positive effect on the auditor's performance which shows that the independent and professional attitude of the auditor is an attitude that must be possessed by an auditor in carrying out an audit.
A Strategic Air Operation as one of the possible instruments in a hybrid war between the Russian Federation against Ukraine
Authors: Horbenko Volodymyr , Korshets Olena
Published: May 2022

The article considers possible options for conducting a hybrid war of the Russian Federation against Ukraine. The analysis of the existing basic concepts of dysfunction of the state system is carried out. Possible options for the influence of the Russian Federation to achieve a political goal in various areas (domains) are identified based on the concepts of strategic paralysis and operation based on effects The article analyses the main factors determining the operating environment conditions in which the Air Force of the Armed Forces of Ukraine will operate. There are analysed modern forces of air attack, means of air defence, tendencies of their development, application, and influence on the present and future operating environment. The threat of conducting combined information and strategic air operation as an effective tool for achieving the political goals of the Russian Federation in Ukraine is substantiated
PENERAPAN STRATEGI PEMBELAJARAN QUANTUM TEACHING SEBAGAI UPAYA MENINGKATKAN KEAKTIFAN BELAJAR MATEMATIKA DI KELAS VII.1 SMP NEGERI 2 AIRPURA
Authors: Elmiyati Elmiyati
Published: May 2022

Penelitian ini bertujuan untuk meningkatkan Keaktifan belajar siswa dalam mata pelajaran Matematika melalui penerapan strategi pembelajaran quantum teachingSMP Negeri 2 Airpura Kabupaten Pesisir Selatan.Penelitian ini tergolong pada PTK yang berlangsung dua siklus setiap siklus terdiri dari tiga kali pertemuan.Disamping itu setiap satu kali pertemuan terdiri dari empat tahapan mulai dari perencanaan, pelaksanaan, observasi dan refleksi.Tindakan dilakukan di kelas VII.1 dimana siswa terdiri dari 31 orang. Peneliti dalam penelitian dibantu oleh seorang observer yaitu yang berperan sebagai pengamat.Data penelitian dianalisis dengan formula persentase yang menggambarkan data sebagai mana adanya. Hasil penelitian meliputi:Pembelajaran Matematika pada siswa kelas VII.1 SMP Negeri 2 Airpura dengan menggunakan strategi pembelajaran Quantum TeachingBerdasarkan hasil penelitian tindakan kelas yang telah dilakukan, maka diambil kesimpulan bahwa tingkat keaktifan siswa sebelum diadakan penelitian tindakan kelas adalah hanya 9 siswa Kata Kunci: Strategi Pembelajaran Quantum  Teaching, Keaktifan Belajar Matematika
ANALISIS PENGARUH PERPUTARAN KREDIT TERHADAP RENTABILITAS EKONOMI (STUDI KASUS PADA KOPERASI PEGAWAI REPOBLIK INDONESIA (KPRI) OBOR KOTA BIMA)
Authors: Hartoyo Hartoyo , Wahyuni Wahyuni
Published: May 2022

Tujuan penelitian ini adalah untuk mengetahui pengaruh perkembangan tingkat perputaran kredit dan tingkat rentabilitas ekonomi pada Koperasi Pegawai Repoblik Indonesia (KPRI) Obor kota Bima. Jenis penelitian yang digunakan dalam penelitian ini adalah studi kasus. Adapun yang menjadi subyek dalam penelitian ini adalah pengurus, pengawas, anggota dan karyawan pada Koperasi Pegawai Repoblik Indonesia (KPRI) Obor Bima untuk di wawancarai mengenai data yang dibutuhkan. Analisis data penelitian ini menggunakan Analisis dinamis yaitu penganalisaan antara pos-pos yang terdapat dalam laporan keuangan pada beberapa periode, atau yang lebih dikenal dengan Analisis rasio koperasi dengan menggunakan Analisis rasio perputaran kredit dan rasio rentabilitas ekonomi.Hasil penelitian menunjukkan bahwa Tingkat perputaran rentabilitas selama kurun waktu tahun 2014 sampai dengan tahun 2018 terus mengalami peningkatan yang signifikan yaitu diatas 100% kecuali Pada tahun 2015 yaitu sebesar 98,92%. Tingkat perputaran kredit mengalami peningkatan setiap tahunnya yaitu mulai tahun 2014 sampai dengan tahun 2018 bahwa rata-rata perputaran kredit dalam setahun seperti yang dianalisis dengan menggunakan rumus  perputaran (RTO) mengalami perputaran di atas seribu kali.
DAMPAK PANDEMI COVID-19 TERHADAP PENDAPATAN EKONOMI PEDAGANG KECIL DI KELURAHAN JATIBARU KECAMATAN ASAKOTA KOTA BIMA
Authors: Arsad Arsad , Burhanuddin Burhanuddin
Published: May 2022

Covid-19 merupakan jenis virus yang penyebarannya sangat cepat sekali, bisa tertular dari manusia ke manusia dari sistem pernapasan atau droplet. Beberapa Negara banyak memberlakukan lockdown, dengan tujuan memutus rantai penularan Covid-19. Menyebabkan jalur perekonomian terhambat dan menyebabkan perekonomian dunia porak-poranda, tidak terlepas pula perekonomian Negara Indonesia. Salah satu sektor ekonomi yang sangat berdampak oleh pandemi Covid-19 adalah sektor Pedagang Kecil. Peneliti mengambil judul dampak pandemi Covid-19 terhadap pendapatan ekonomi pedagang kecil di Kelurahan Jatibaru Kecamatan Asakota Kota Bima. Rumusan masalah yang di teliti adalah Bagaimana dampak pandemi Covid-19 terhadap pendapatan ekonomi pedagang kecil di Kelurahan Jatibaru Kecamatan Asakota Kota Bima? Tujuan Penelitian yang akan di teliti adalah untuk Mengetahui Bagaimanakah dampak pandemic covid-19 terhadap pendapatan ekonomi pedagang kecil di Kelurahan Jatibaru, Kecamatan Asakota, Kota Bima.

Penelitian ini adalah penelitian kualitatif dengan pendekatan deskriptif. Untuk mendapatkan data yang diperlukan maka dilakukan penelitian dengan cara mewawancarai pedagang, setelah data-data diperoleh maka dilakukan pengujian dengan menggunakan teknik analisis data kualitatif.

            Berdasarkan hasil penelitian dan pembahasan maka kesimpulan yang penulis simpulkan adalah selama tersebarnya pandemic covid-19 yang berpengaruh negative dan kalau dipersentasikan ada sebanyak 73% yang mengeluh karena pelanggan berkurang, ada 46% yang mengeluh karena kesulitan dalam mendapatkan modal usaha dan ada 40% yang mengeluh karena tidak bisa menerima pelanggan ditempat seperti biasa. PPKM (Pemberlakuan pembatasan kegiatan masyarakat) membuat banyak outlet yang jam operasionalnya dikurangi, apalagi semenjak masyarakat disuruh dirumah aja mereka lebih banyak memilih untuk mengurangi aktivitas di luar sehingga para pedagang kecil ini mengalami kerugian akibat berkurangnya pembeli dan menurunya pendapatan.
Strategic competence of junior high school students in solving geometry problems reviewed from sex differences
Authors: Firdiana Winda , Juniati Dwi , Janet Trineke Manoy
Published: May 2022

Penelitian ini bertujuan untuk mendeskripsikan kompetensi strategis siswa SMP dalam menyelesaikan masalah geometri ditinjau dari perbedaan jenis kelamin. Indikator yang dinilai meliputi merumuskan, merepresentasikan dan memecahkan masalah. Subjek penelitian ini yaitu 1 siswa laki-laki dan 1 siswa perempuan kelas IX-F SMPN 1 Tulangan yang memiliki kemampuan setara. Selanjutnya subjek mengerjakan tugas pemecahan masalah geometri. Hasil penelitian menunjukkan bahwa kedua subjek memahami masalah dengan membaca dan menggambar. Pada soal pertama, kedua subjek merepresentasikan masalah dengan mengarsir, menghitung luas gudang dan lahan menggunakan luas persegi panjang kemudian memecahkan masalah dengan menghitung luas rumput yang dipotong dikalikan biaya jasa pemotongan. Namun, subjek perempuan tidak menggambarkan bentuk benda secara akurat dan tidak memberikan alasan tepat mengenai bentuk yang telah digambarkan. Pada soal kedua, kedua subjek salah memilih strategi dalam merepresentasikan masalah karena tidak mampu membuat susunan kardus lain, akibatnya proses memecahkan masalah bernilai salah. Siswa perlu dilatih soal geometri non-rutin bangun ruang untuk mengembangkan kompetensi strategisnya.
Two Approaches of Measuring Intra-industry Trade
Authors: Dutta Sourish
Published: May 2022

This paper deals with the problem of measuring intra-industry trade. In section 2, it presents two existing approaches (Balboni, 2007) to measuring intra-industry trade: the so called “recovery of trade”, developed by Balassa (1966); Grubel and Lloyd (1975) & the “type of trade” one initiated by Abd-el Rahman (1986b); Vona (1991). Then this paper presents indicators and empirical methods inspired by these two approaches. Notions of trade recovery & trade type come from two different definitions of the empirical phenomena they aim to measure. This paper also discusses these definitions and the theoretical foundations in the section 3.
Comprehensive Analyses of MELK-Associated ceRNA Networks Reveal a Potential Biomarker for Predicting Poor Prognosis and Immunotherapy Efficacy in Hepatocellular Carcinoma
Authors: Liu Yu , Li Rongkuan , Wang Xiaobo , Xue Zuguang , Yang Xiaozhou , Tang Bo
Published: May 2022

Background: Hepatocellular carcinoma (HCC) is one of the most common malignant tumors in the world with high morbidity and mortality. Identifying specific molecular markers that can predict HCC prognosis is extremely important. MELK has been reported to play key roles in several types of human cancers and predict poor prognosis. This study was aimed to explore the impact of MELK on HCC.

Methods: A pan-cancer analysis of MELK was conducted by The Cancer Genome Atlas (TCGA) and the Genotype-Tissue Expression (GTEx) data. The prognosis of MELK in various cancers was analyzed in GEPIA. Then, a ceRNA network of MELK was constructed based on the comprehensive consideration of the expression analysis, the correlation analysis, and the survival analysis by R software. The correlation of MELK and immune cell infiltration was analyzed by TIMER and ﻿CIBERSORT. Then, the overall survival of differentially expressed immune cells was conducted. The correlation of MELK and immune checkpoints expression was analyzed by GEPIA.

Results: MELK was overexpressed in 14 types of human cancers, and its expression was significantly higher than that in both unmatched and paired normal samples in HCC. Higher MELK expression was correlated with poorer survival and advanced clinical stage, topography (T) stage, and histological grade. The univariate and multivariate Cox regression analyses showed that MELK was an independent risk factor for poor prognosis in HCC. Then, we constructed a ceRNA network consisting of MELK, miR-101-3p, and two lncRNAs (SNHG1 and SNHG6) after evaluating the expression and impact on prognosis in HCC of these RNAs. TIMER and CIBERSORT databases indicated that MELK was correlated with various immune cells including B cells, CD8+ T cells, CD4+ T cells, macrophage, neutrophil, and dendritic cells in HCC. Of them, B cells, CD4+ T cells, macrophage, and neutrophil were related to the prognosis of HCC. In addition, MELK was significantly positively correlated with the immune checkpoint genes.

Conclusions: MELK may be a novel potential biomarker for predicting prognosis and immunotherapy efficacy in patients with HCC. Our study may provide new molecular and therapeutic strategies for the treatment of HCC patients.
Multifunctional Core-Shell Microgels as Pd-Nanoparticle Containing Nanoreactors With Enhanced Catalytic Turnover
Authors: Sabadasch Viktor , Dirksen Maxim , Fandrich Pascal , Hellweg Thomas
Published: May 2022

In this work, we present core-shell microgels with tailor-made architecture and properties for the incorporation of palladium nanoparticles. The microgel core consists of poly-N-isopropylacrylamide (PNIPAM) copolymerized with methacrylic acid (MAc) as anchor point for the incorporation of palladium nanoparticles. The microgel shell is prepared by copolymerization of NIPAM and the UV-sensitive comonomer 2-hydroxy-4-(methacryloyloxy)-benzophenone (HMABP). The obtained core-shell architecture was analyzed by means of photon correlation spectroscopy, while the incorporated amount of HMABP was further confirmed via Fourier transform infrared spectroscopy. Subsequently, the microgel system was used for loading with palladium nanoparticles and their size and localization were investigated by transmission electron microscopy. The catalytic activity of the monodisperse palladium nanoparticles was tested by reduction of 4-nitrophenol to 4-aminophenol. The obtained reaction rate constants for the core-shell system showed enhanced activity compared to the Pd-loaded bare core system. Furthermore, it was possible to recycle the catalyst several times. Analysis via transmission electron microscopy revealed, that the incorporated palladium nanoparticles emerged undamaged after the reaction and subsequent purification process since no aggregation or loss in size was observed.
Accelerated Cardiac Aging in Patients With Congenital Heart Disease
Authors: Iacobazzi Dominga , Alvino Valeria Vincenza , Caputo Massimo , Madeddu Paolo
Published: May 2022

An increasing number of patients with congenital heart disease (CHD) survive into adulthood but develop long-term complications including heart failure (HF). Cellular senescence, classically defined as stable cell cycle arrest, is implicated in biological processes such as embryogenesis, wound healing, and aging. Senescent cells have a complex senescence-associated secretory phenotype (SASP), involving a range of pro-inflammatory factors with important paracrine and autocrine effects on cell and tissue biology. While senescence has been mainly considered as a cause of diseases in the adulthood, it may be also implicated in some of the poor outcomes seen in patients with complex CHD. We propose that patients with CHD suffer from multiple repeated stress from an early stage of the life, which wear out homeostatic mechanisms and cause premature cardiac aging, with this term referring to the time-related irreversible deterioration of the organ physiological functions and integrity. In this review article, we gathered evidence from the literature indicating that growing up with CHD leads to abnormal inflammatory response, loss of proteostasis, and precocious age in cardiac cells. Novel research on this topic may inspire new therapies preventing HF in adult CHD patients.
Evaluation of the Effectiveness and Adaptability of a Composite Water Control Process for Horizontal Wells in Deepwater Gas Reservoirs
Authors: Wang Dianju , Li Yihe , Ma Lan , Yu Fahao , Liu Shufen , Qi Tong , Jiang Siyuan
Published: May 2022

Deepwater gas fields have high bottom water energy and a high risk of seeing water. Higher requirements are put forward for the water control process to control the water effect. This article is based on the actual background and well design of the X gas field in the South China Sea and on three sets of physical simulation experiments and three sets of numerical simulation experiments. An analysis and comparison of the water control effect of a combination of continuous packer, continuous packer and variable density screen tube, and their adaptability evaluation in deepwater gas reservoirs were performed. The results obtained from the numerical and physical simulations are consistent. The experimental results show that the water control process of a continuous packer is mainly based on the water-seeing and water-blocking ability. It is less capable of extending the time to produce water in the horizontal section. However, its water-blocking ability is strong and is able to seal the water spot quickly. It extends the total production time by 12.29% and increases the total gas production by 5.96%; the combined water control process of the continuous packer and variable density screen tube can effectively play their respective advantages of water control. The combination of the continuous packer and variable density screen tube can effectively be advantageous of their respective water control processes, enabling the gas–water interface to advance in a balanced manner, extending the water-free gas recovery period by 11.61%, extending the total gas production time by 15.76%, and increasing the total gas production volume by 13.75%. Both water control processes have good applicability in deepwater gas fields and have certain sand control capability. It is conducive to the one-time completion operation for the commissioning of deepwater gas fields.
Relational Narrative Inquiry Alongside a Young Métis Child and Her Family: Everyday Assessment Making, Pimatisiwin, Pimosayta, and Teacher Education and Development
Authors: Huber Janice , Cardinal Trudy , Murphy M. Shaun
Published: May 2022

Understandings of diverse children, families, and communities/peoples as holding knowledge of and as practicing assessment is little recognized in research for, or in programs of, teacher education and development. Our paper shows the intergenerational relational living that Suzy, a young Métis child, experienced alongside her family as they imagined forward and remembered backward. This process shaped, and was shaped by, the family and Suzy’s continuous assessment of her ongoing making of a healthy life. We see important connections between Suzy’s and her family’s everyday assessment making practices and our experiences alongside Anishinaabe kwe scholar Mary Isabelle Young (Singing Turtle Woman), who lived with usPimatisiwin(walking in a good way) andPimosayta(learning to walk together). Dominant narratives of accountability in universities and schools most commonly serve the institution or government. Much potential opens in teacher education and development when we shift from these orientations to orientations that lift the particularities of each person and our collective responsibilities to all our relations. In this way we move closer to fulfilling our responsibilities to the people and worlds around us, to all of creation, the animals, plants, Earth, and cosmos, and to the next generations.
Relationship of Soluble Klotho and Early Stage of Diabetic Nephropathy: A Systematic Review and Meta-Analysis
Authors: Xin Caihong , Sun Xin , Li Zheng , Gao Tianshu
Published: May 2022

Background

Diabetic nephropathy (DN) is a chronic microvascular complication caused by long-term hyperglycemia in patients with diabetes and an important cause of end-stage renal disease. Although some studies have shown that soluble Klotho(sKlotho) levels of patients with DN are lower than those without DN, in the early stage of patients with DN with normal renal function and albuminuria, the change in sKlotho is still controversial.

Aim

This meta-analysis was conducted to statistically evaluate sKlotho levels in patients with DN.

Methods

We searched the following electronic databases: Web of Science, Embase, PubMed, Google Scholar, and China National Knowledge Infrastructure (CNKI). The following search terms were used for the title or abstract: “diabetic kidney disease”, “diabetic nephropathy”, OR “DN” in combination with “Klotho”. The meta-analysis results were presented as standardized mean differences (SMDs) with corresponding 95% confidence intervals (CIs).

Results

Fourteen articles were included in the meta-analysis. In our meta-analysis, we found that the sKlotho level in patients with DN was significantly lower than that in patients without DN (SMD: -1.52, 95% CI [-2.24, -0.80]), and it was also significantly lower in the early stage of DN (SMD: -1.65, 95% CI [-2.60, -0.70]).

Conclusions

This systematic review was the first to evaluate the relationship between sKlotho levels and DN. The sKlotho level was significantly lower in the early stages of DN, indicating that sKlotho might be a new biomarker of DN in the future.
Hybrid Short-Term Wind Power Prediction Based on Markov Chain
Authors: Zhou Liangsong , Zhou Xiaotian , Liang Hao , Huang Mutao , Li Yi
Published: May 2022

This article proposes a combined prediction method based on the Markov chain to realize precise short-term wind power predictions. First, three chaotic models are proposed for the prediction of chaotic time series, which can master physical principles in wind power processes and guide long-term prediction. Then, considering a mechanism switching between different physical models via a Markov chain, a combined model is constructed. Finally, the industrial data from a Chinese wind farm were taken as a study case, and the results validated the feasibility and superiority of the proposed prediction method.
Extended-Range Forecasting of PM2.5 Based on the S2S: A Case Study in Shanghai, China
Authors: Qu Yuanhao , Ma Jinghui , Yu Zhongqi
Published: May 2022

Air pollution has become one of the most challenging problems in China, especially in economically developed and densely populated regions such as Shanghai. In this study, the long short-term memory (LSTM) model is introduced for the application in extended-range forecasting of PM2.5 in Shanghai by incorporating three members of the Subseasonal-to-Seasonal Prediction project (S2S) forecasting, moderate-resolution imaging spectroradiometer (MODIS) aerosol optical depth (AOD) data, and large-scale circulation factors derived from ERA-5 reanalysis. Therefore, an accurate ∼40-day PM2.5 prediction model over Shanghai was developed, providing new insights for air pollution extended-range forecasting. The new model not only exhibited much better accuracy but also captured the pollution process more closely than traditional methods, such as multiple regression (MLR). The prediction root-mean-square errors (RMSEs) based on the China Meteorological Administration (CMA), the U.K. model, and the European Centre for Medium-Range Weather Forecasts (ECMWF) were 24.84, 24.35, and 22.27 μg m−3, respectively, and their Heidke Skill Scores (HSSs) were between 0.1 and 0.5. As a result, the S2S-LSTM model for extension period pollution prediction with higher accuracy developed in this study could further burst the hot spots of pollution extended-range prediction research. However, limitations of the prediction model are still in existence, especially in dealing with only a single site instead of a two-dimensional prediction, which requires further investigation in future studies.
Comprehensive Molecular Analyses of a Macrophage-Related Gene Signature With Regard to Prognosis, Immune Features, and Biomarkers for Immunotherapy in Hepatocellular Carcinoma Based on WGCNA and the LASSO Algorithm
Authors: Wang Tao , Dai Liqun , Shen Shu , Yang Yi , Yang Ming , Yang Xianwei , Qiu Yiwen , Wang Wentao
Published: May 2022

Macrophages have been reported to exert a crucial role in hepatocellular carcinoma (HCC). This study aimed to explore the macrophage-related genes and establish a macrophage-related signature (MRS) model to predict the overall survival (OS) of patients with HCC based on these genes’ expression. We screened the macrophage-related gene module by weighted gene coexpression network analysis (WGCNA), the least absolute shrinkage and selection operator (LASSO) Cox regression analysis was utilized for further selection, and the selected genes were entered into stepwise regression to develop the MRS model, which was further validated in the Gene Expression Omnibus (GEO) and International Cancer Genome Consortium (ICGC) datasets. We analyzed the biological phenotypes associated with macrophages in terms of functional enrichment, tumor immune signature, and tumor mutational signature. The patient’s response to immunotherapy was inferred by the tumor immune dysfunction and exclusion (TIDE) score, the immunophenotype score (IPS), and the IMvigor210 dataset. A novel MRS model was established based on the LASSO regression coefficients of the genes PON1, IL15RA, NEIL3, HILPDA, PFN2, HAVCR1, ANXA10, CDCA8, EPO, S100A9, TTK, KLRB1, SPP1, STC2, CYP26B1, GPC1, G6PD, and CBX2. In either dataset, MRS was identified as an independent risk factor for OS in HCC patients. Additionally, our research indicated that a high-risk score in the MRS model was significantly correlated with tumor staging, pathological grade, tumor–node–metastasis (TNM) stage, and survival. Several genes of the human leukocyte antigen (HLA) family and immune checkpoints were highly expressed in the high-risk group. In addition, the frequency of tumor mutations was also higher in the high-risk group. According to our analyses, a higher risk score in the MRS model may predict a better response to immunotherapy.
The Olfactory Organ Is a Unique Site for Neutrophils in the Brain
Authors: Palominos M. Fernanda , Calfún Cristian , Nardocci Gino , Candia Danissa , Torres-Paz Jorge , Whitlock Kathleen E.
Published: May 2022

In the vertebrate olfactory tract new neurons are continuously produced throughout life. It is widely believed that neurogenesis contributes to learning and memory and can be regulated by immune signaling molecules. Proteins originally identified in the immune system have subsequently been localized to the developing and adult nervous system. Previously, we have shown that olfactory imprinting, a specific type of long-term memory, is correlated with a transcriptional response in the olfactory organs that include up-regulation of genes associated with the immune system. To better understand the immune architecture of the olfactory organs we made use of cell-specific fluorescent reporter lines in dissected, intact adult brains of zebrafish to examine the association of the olfactory sensory neurons with neutrophils and blood-lymphatic vasculature. Surprisingly, the olfactory organs contained the only neutrophil populations observed in the brain; these neutrophils were localized in the neural epithelia and were associated with the extensive blood vasculature of the olfactory organs. Damage to the olfactory epithelia resulted in a rapid increase of neutrophils both within the olfactory organs as well as the central nervous system. Analysis of cell division during and after damage showed an increase in BrdU labeling in the neural epithelia and a subset of the neutrophils. Our results reveal a unique population of neutrophils in the olfactory organs that are associated with both the olfactory epithelia and the lymphatic vasculature suggesting a dual olfactory-immune function for this unique sensory system.
Borrelia miyamotoi FbpA and FbpB Are Immunomodulatory Outer Surface Lipoproteins With Distinct Structures and Functions
Authors: Booth Charles E. , Powell-Pierce Alexandra D. , Skare Jon T. , Garcia Brandon L.
Published: May 2022

Pathogens that traffic in the blood of their hosts must employ mechanisms to evade the host innate immune system, including the complement cascade. The Lyme disease spirochete,Borreliella burgdorferi, has evolved numerous outer membrane lipoproteins that interact directly with host proteins. Compared to Lyme disease-associated spirochetes, relatively little is known about how an emerging tick-borne spirochetal pathogen,Borrelia miyamotoi, utilizes surface lipoproteins to interact with a human host.B. burgdorferiexpresses the multifunctional lipoprotein, BBK32, that inhibits the classical pathway of complement through interaction with the initiating protease C1r, and also interacts with fibronectin using a separate intrinsically disordered domain.B. miyamotoiencodes two separatebbk32orthologs denotedfbpAandfbpB; however, the activities of these proteins are unknown. Here, we show thatB. miyamotoiFbpA binds human fibronectin in a manner similar toB. burgdorferiBBK32, whereas FbpB does not. FbpA and FbpB both bind human complement C1r and protect a serum-sensitiveB. burgdorferistrain from complement-mediated killing, but surprisingly, differ in their ability to recognize activated C1r versus zymogen states of C1r. To better understand the observed differences in C1r recognition and inhibition properties, high-resolution X-ray crystallography structures were solved of the C1r-binding regions ofB. miyamotoiFbpA and FbpB at 1.9Å and 2.1Å, respectively. Collectively, these data suggest that FbpA and FbpB have partially overlapping functions but are functionally and structurally distinct. The data presented herein enhances our overall understanding of how bloodborne pathogens interact with fibronectin and modulate the complement system.