bluuebunny/crossref_metadata_2025 huggingface dataset:
The use of hydrogen purification and mixture of cosmetics acids, and the influence on acne skin parameters: a case report.
Authors: Leja Dominika , Dziedzic Katarzyna , Chilicka Karolina , Golombek Mirella , Niestrój Karolina , Połednik Hanna , Koznarska-Buczkowska Agnieszka , Rusztowicz Monika , Adamczyk Ewa
Published: April 2022

Background: Acne vulgaris is a common disease which causes physical and mental ailments that are associated with a significantly reduced quality of life. Contemporary cosmetology is looking for innovative and effective methods of treating acne vulgaris. The synergistic action of acids and hydrogen purification has a positive effect on the reduction of sebum secretion and thus the amount of skin eruptions.
The aim of the study : To check the effectiveness of hydrogen purification treatment combined with topical acids for the treatment of acne vulgaris.
Case report: The participant of this study is a 20-year-old female, struggling with acne vulgaris for 5 years. She has a problem with large sebum secretion and numerous eruptions on her skin. Before and 30 days after a series of treatments the sebum secretion was measured with Derma Unit SCC 3Courage + Khazaka electronic GmbH, which characterizes the hydrolipidic film of the skin. The severity of acne vulgaris was measured using the GAGS scale.
Conclusions: There was a significant improvement in skin condition after a series of treatments. Hydrogen purification combined with phytic, pyruvic, lactic and ferulic acids 40% (pH 1.4) was found to be safe and effective.
A Conceptual Framework for Understanding Democracy Dimensions in Public Spaces: The Case of 30Tir Street in Tehran
Authors: Asadi Navid , Razzaghi Asl Sina
Published: April 2022

Cities and public spaces should be regarded as the most valuable achievements of mankind in recent centuries. Nowadays, in some cases, we see a decline in quality of the public sphere, which diminishes the liberty and the voluntary presence of people, who feel no desire to visit certain public spaces. In this paper, we critically review existing knowledge and attitudes applied within the broadly defined field of democratic public spaces and develop a new, more comprehensive framework that better reflects contemporary social challenges in the city of Tehran, Iran. We systemized and unified a broad range of urban democracy-based concepts in an integrated model, i.e., the right to the city, social justice, civil society and citizen’s rights, inclusive design and cities friendly for women, children, the elderly, the disabled, tourists, and minority groups within the city. Data collection was conducted based on the crowdsourcing method through analysis of social networking applications, i.e., Twitter, Instagram, and Foursquare as well as in-depth and semi-structured interviews with experts and the public. As a result, we systematically distinguish five key terms for assessing democratic public spaces, i.e., socio-spatial diversity, social justice, social inclusion, comfort, and public participation. This conceptual framework can be used as a guideline for policy makers and urban designers to create and evaluate public spaces to achieve the most democratic spaces. Our framework was applied to Tehran’s 30Tir street.
A criação da Escola de Artes Fritz Alt e da Escolinha de Artes Infantis na cidade das indústrias
Authors: Gonçalves Juliana Rossi , Moraes Taiza Mara Rauen
Published: April 2022

O presente artigo é decorrente de uma pesquisa documental e bibliográfica sobre a criação da Escola de Artes Fritz Alt (EAFA), localizada em Joinville (SC), como uma das ações do movimento de industrialização ocorrido na cidade nas décadas de 1960 e 1970. O estudo desvela que no referido período histórico circulou um discurso desenvolvimentista mobilizado para justificar a criação da Escola. Por sua vez, a Escolinha de Artes Infantis (EAI) foi criada dentro da EAFA em 1970, como um reflexo do Movimento Escolinhas de Arte (MEA) do Brasil, o qual se constituiu por meio da criação de várias escolinhas de arte em todo o território brasileiro, que se transformaram em ateliês de produção artística para crianças. A EAFA, bem como a EAI, é subsidiada pela prefeitura municipal e resiste há mais de 50 anos em uma cidade industrial, apesar dos mo(vi)mentos de tensão e de lutas de seus artistas-professores, funcionários e alunos.
Contribuições da Teoria Desenvolvimental para o ensino escolar da Arte
Authors: Biavatti Sandra Macanhão , Szymanski Maria Lidia
Published: April 2022

O presente artigo apresenta um estudo teórico, objetivando analisar os principais conceitos que fundamentam a ação pedagógica do docente de Arte, a partir da Psicologia Histórico-Cultural e da Teoria Desenvolvimental. Discutem-se os conceitos de atividade, desenvolvimento psíquico e humanização como promotores do desenvolvimento das funções psicológicas superiores, entre as quais a criação e a fruição. Trata-se de um ensino organizado que atua na zona de desenvolvimento iminente, atualizando-a e ampliando-a gradativamente, visando o pensamento teórico e o desenvolvimento do sujeito como partícipe do gênero humano. Apresentam-se, ainda, as pesquisas desenvolvidas com esse referencial, no período de 2011 a 2021, voltado à disciplina de Arte, destacando as ações pedagógicas propostas para uma educação que promova o desenvolvimento da sensibilidade e percepção estética, objetivando o ser humano genérico, comprometido com um projeto de sociedade menos excludente.
A arte e os blocos de sensações: as experimentações e a criação não representativa
Authors: Costa Thaís Thaianara Oliveira da , Christofoletti Rafael
Published: April 2022

Este texto é parte de uma pesquisa de mestrado que se configura com experimentações artísticas e rodas de conversas com alunos, professoras e professores da rede pública municipal de Porto Velho, Rondônia. Tem como objetivo principal discutir como se articula o ensino de arte nos anos iniciais do Ensino Fundamental. Para essa conversa, são convidados autores das filosofias da diferença pelas obras de Deleuze (1981), Deleuze e Guattari (2010) e Lins (2008, 2012), que atravessam a todo o momento, compondo com as experimentações artísticas que se movimentam, navegam e transbordam em pensamentos reverberantes, se despindo dos métodos e possibilitando outros modos de fazer pesquisa. Assim, o processo de criação se mostrou potente quando realizado coletivamente, sem direcionamentos e movimentos pré-definidos. Apresentaram-nos um cotidiano escolar permeado por acontecimentos, fugas das regras e aprisionamentos que estratificam a potência da arte, fugindo às tentativas de controle e se compondo com os blocos de sensações no processo de criação artística.
Montes sagrados: uma viagem pela iconologia portuguesa
Authors: Brandão Jack
Published: April 2022

As montanhas sempre fascinaram os homens desde antes da efetivação do lógos, transmitindo-lhes medo, devoção e respeito. Devido a isso, diversas interpretações mítico-religiosas foram criadas, tendo tais elevações como elementos-chave: seja como representação da divindade, sua morada, ou locais para suas teofanias. Assim, o cristianismo, como o judaísmo de onde surgiu, não ficou alheio a essa peregrinação aos locais sagrados, muitos dos quais montes. Por volta do ano 1000 de nossa era, os peregrinos cristãos ansiavam por dirigir-se a Jerusalém, como forma de expiar seus pecados na virada do novo milênio que se aproximava, no entanto, os turcos otomanos dificultaram tal acesso, levando os fiéis europeus a buscarem novas alternativas para expressar sua fé, como os montes sagrados. Dessa maneira, este artigo visa a compreender como se efetivou este processo, buscando resgatar elementos iconográficos e iconológicos que se dispersaram devido à ação do tempo, a fim de que pesquisadores e estudantes brasileiros possam ter acesso a esse manancial logo-imagético também presente em nosso fazer artístico. Para isso, empreendeu-se, de modo especial, uma pesquisa logo-imagética, a partir das considerações iconográficas de Cesare Ripa (2007a, 2007b).
O que podemos (des)aprender com a arte? Saberes estético-corpóreos e a construção de outro(s) conhecimento(s)
Authors: Benatti Lucas Men , Teruya Teresa Kazuko , Maio Eliane Rose
Published: April 2022

Nesta pesquisa, amparados pela arte, pelos Estudos Culturais e pela ciência, buscamos apresentar um breve percurso epistemológico da constituição científica ocidental e suas articulações com os saberes estético-artísticos. Procuramos propor novas conexões possíveis da ciência com a arte em perspectiva pós-colonial e pós-moderna, de conhecimentos e estéticas à margem dos paradigmas eurocêntricos e que assumem a virtualidade política e ética no agenciamento de novos sujeitos e histórias. É no interior deste campo epistemológico que problematizamos: de quais modos os saberes estético-corpóreos potencializam a produção de outro(s) conhecimento(s)? Como dispositivo reflexivo, encontramos na arte barroca brasileira (período histórico da colonização) e, especificamente, na pintura do Papa negro, presente no interior da Igreja de Santa Efigênia, em Ouro Preto-MG, a materialização de saberes estético-corpóreos como metáforas de transformação. Isto é, caminhos abertos que nos permitem imaginar como seria o mundo se os valores culturais predominantes fossem questionados e transformados.
Patrimônio cultural e educação estética: os sentidos da cidade na percepção de docentes
Authors: Rodrigues Hugo de Melo , Sales José Albio Moreira de , Rodrigues Cicera Sineide Dantas
Published: April 2022

A relação entre patrimônio cultural e educação estética na formação de professores é o tema central deste estudo. Assim, a presente pesquisa buscou conhecer a concepção de docentes do ensino básico sobre patrimônio cultural; além de identificar aspectos reflexivos da docência, emergentes do ato de sentir a cidade, por meio de uma atividade em que os participantes caminharam pelas ruas de olhos vendados. Com base na abordagem qualitativa de pesquisa, optou-se pelo método da pesquisa-ação colaborativa. A formação experienciada promoveu reflexões importantes sobre o patrimônio cultural. Considera-se a relevância de integrar discussões sobre patrimônio cultural e educação estética nos currículos da formação inicial e continuada de professores, norteando-se por paradigmas que valorizem dimensões éticas, estéticas e colaborativas.
Nutrientes na serapilheira acumulada em quatro clones de eucalipto em sistema de Integração Lavoura-Pecuária-Floresta (ILPF)
Authors: Velozo Amanda Prudente , Pacheco Abílio Rodrigues , Calil Francine Neves , Silva-Neto Carlos de Melo
Published: April 2022

O objetivo deste estudo foi avaliar a produção de biomassa e estoque de nutrientes na serapilheira acumulada em plantios de quatro clones de eucalipto (AEC-2034 (Eucalyptus camaldulensis x E. grandis) x E. urophylla)), AEC-2111 (E. urophylla x (E. camaldulensis x E. grandis)), AEC-007 (E. toreliana x E. citriodora) e o AEC-0043 (E. citriodora x E. toreliana) aos quatro anos e meio, em sistema integrado de Lavoura-Pecuária-Floresta (ILPF), em Inaciolândia – Goiás. Para a coleta de serapilheira (folhas, galhos, casca e miscelânea) foi utilizado um gabarito de área de 0,0625 m². Foram coletadas 20 amostras de serapilheira aleatoriamente em cada clone, totalizando 80 amostras. Em laboratório, todo material foi processado através de secagem, pesagem e moagem para determinação de biomassa e análises de teor nutricional. O acúmulo na produção média total de serapilheira acumulada foi de 6,07 Mg ha-1 para o clone AEC-2034, 5,20 Mg ha-1 para o clone AEC-2111, 3,41 Mg ha-1 para o clone AEC-007 e 3,23 Mg ha-1 para o clone AEC-0043. O componente folha apresentou o maior acúmulo total de nutrientes em todos os clones. O nitrogênio (N) foi o elemento com maior estoque na serapilheira acumulada em todos os clones. O maior acúmulo de biomassa de serapilheira ocorreu no clone AEC-2034 e o componente mais representativo foi a folha. O clone AEC-2034 apresentou maior estoque de nutrientes na serapilheira e o clone AEC-0043 o menor estoque. O macronutriente com maior acúmulo nos componentes avaliados foi o nitrogênio (N) e o micronutriente foi o ferro (Fe). Com base no acúmulo de serapilheira e devolução de nutrientes, o clone mais indicado em sistema ILPF nessa região é o clone AEC-2034.
Engine propeller matching analysis on Fishing Vessel using inboard engine
Authors: Wibawa Budi , Fathan Mausulunnaji , Setiyobudi Nanang , Chrismianto Deddy , Sasmito Hadi
Published: April 2022

Fishing vessels which are used for one day operations usually use outboard engines as their driving motor. However, to improve the performance of propulsion systems, and consequently the performance of ships, inboard engines are now being used. In this study, the propulsion system of a ship was modified by upgrading from an outboard to an inboard motor. Meanwhile, the study aims to obtain an optimal interaction between the propulsion system and the hull shape of the ship. It was conducted by calculating the ship's resistance using the van Oortmerssen method, and validating the result using the CFD method. Furthermore, thrust and torque calculations were performed to obtain the characteristics of the ship's propellers, and the results were validated using the CFD method. The result obtained from the calculation of the ship's resistance was a New Fishing Vessel engine power of 11 HP. 4 types of B-Series propellers characterized based on the size of their pitch, including 14.00 inch, 14.25 inch, 14.50 inch, and 14.75 inch were, analyzed using the engine propeller matching analysis. The results show that the propeller with the pitch size of 14.75 inches was the best, as it had a power of 100%, speed of 25.35%, and efficiency of 32%. Therefore, it was chosen as the new propeller for New Fishing Vessels.
Body composition in Serbian police officers
Authors: Vuković Marko , Subošić Dane , Đorđević-Nikić Marina , Dopsaj Milivoj
Published: April 2022

Background. Police work belongs to the category of exceptionally responsible and psychologically , socially and physically strenuous and stressful professions. Occupational pressures can lead to a significant negative change in the level of nutrition, thus affecting body structure. Therefore, the goal of this paper was to analyze body composition in Serbian police personnel as related to their professional duties. Methods. 689 healthy male participants took part in this research, a control group of 412 civilians, and a group consisting of 277 male members of the Ministry of Interior of the Republic of Serbia, divided into 4 subgroups: Uniformed Police Administration (Directorate) (N = 38), Police Brigade (N = 127), Gendarmerie (N = 59) and Special Anti-Terrorist Unit (N = 53). The body composition measurements were realized by using multichannel segmental bioimpedance with InBody 720 apparatus. Results. Regarding different components of body fat, in comparison to the control group, police officers were found to have a higher value of BFM-body fat mass, VFA-visceral fat area, and BFI-body fat index, as well as a lower value of PFI-protein fat index. Conclusions. In view of the fact that body fat is a ballast component in good locomotion and a health risk factor in case of large or extreme surplus, we believe that this problem should be solved systematically through permanent evaluation, improved dietary habits and more regular and intensive physical activity.
Maciunas
Authors: Wilmer Stephen Elliot
Published: April 2022

Fluxus was an inspirational movement based in New York in the 1960s that consisted of a group of more than fifty loosely connected artists from various disciplines, who made significant experiments to develop music, conceptual art, visual art, performance art, video, and film. They participated in eclectic concerts, media, performative events, and installations in the USA and Europe. In this paper, I want to examine how George Maciunas, a Lithuanian exile and its nominal organiser, had a seminal influence on avant-garde art in America and Europe and, despite avowing an open attitude towards what could be art, he also enforced draconian ideas about what could be included and what could not. In particular I want to emphasize his influence in Scandinavia because most of the literature on Fluxus has focused on his work in the USA and Germany.
Aesthetics and Dramaturgies of Immersive and Interactive Theatre Since the Turn of the Millennium
Authors: Skjoldager-Nielsen Kim
Published: April 2022

Since the turn of the millennium, stage art has seen an increased interest in adopting and developing interactive and immersive aesthetics. Thisarticle offers a comparative study of two Danish groups, SIGNA and Sisters Hope, and one Swedish group, Poste Restante. The visual dimension of theperformances by these three groups is striking, which may be partly attributed to the interconnections between the artists that has allowed a flow of ideasand strategies to occur between one group and the other. Looking at these connections, it appears that there is a line going from SIGNA (established in2001) to Poste Restante (established in 2007) and to Sisters Hope (established in 2014). Whilst there are similarities, there are also great differences in termsof the aesthetics and dramaturgies of these groups, which reflect political, ethical, and ideological differences in the context of Nordic societies. The paperinvestigates these aspects through their relations to the audience: how is the audience included in a performance? And what is the purpose of applying aninteractive and immersive aesthetics?
Cross-border corporate agreement: cross-border issues
Authors: Zaria Aleksandr Andreevich
Published: April 2022

The subject of the study is the legal relations that develop between the participants of a corporate agreement with a foreign element. Due to the specifics of this type of contract, not all types of foreign element lead to a cross-border nature, moreover, the amount of a person's participation in the authorized capital of a corporation matters. The issues of changes in the applicable law leading to the impossibility of execution of the corporate contract and the ways in which it is possible to protect the parties from these adverse consequences are investigated. The article analyzes the consequences of the special "volatility" of a corporate contract, which consists in the fact that it is more susceptible to various changes in the foreign element, in particular, related to the exit of a foreign participant from the corporation, the relocation of the corporation, the redomicilation procedure. The methodological basis of the research is the universal dialectical, logical, formal-legal, hermeneutic research methods. The comparative legal method was also used by involving the practice of conflict-of-laws regulation of the countries of the common system of law and Germany. The novelty of the study lies in the fact that mechanisms have been developed to maintain the balance of interests of the parties to a corporate contract with changes in applicable law, the consequences of relocation and redomicilation of the corporation have been determined, a proposal has been put forward on the amount of the participation share of a foreign participant necessary for the recognition of the contract as cross-border. The main conclusions are the following provisions: when determining the cross-border nature of a corporate contract, it is necessary to apply both a legal and an economic approach; the best way to level the risks of changes in applicable law is a conditional choice of applicable law; to determine the materiality of a foreign element, it is necessary to be guided by the norms of corporate legislation on dependent companies; relocation and redomicilation do not lead to a change in the conflict of laws choice of applicable law.
A transcriptomic atlas of Aedes aegypti reveals detailed functional organization of major body parts and gut regional specializations in sugar-fed and blood-fed adult females
Authors: Hixson Bretta , Bing Xiao-Li , Yang Xiaowei , Bonfini Alessandro , Nagy Peter , Buchon Nicolas
Published: April 2022

Mosquitoes transmit numerous pathogens, but large gaps remain in our understanding of their physiology. To facilitate explorations of mosquito biology, we have created Aegypti-Atlas (http://aegyptiatlas.buchonlab.com/), an online resource hosting RNAseq profiles of Ae. aegypti body parts (head, thorax, abdomen, gut, Malpighian tubules, ovaries), gut regions (crop, proventriculus, anterior and posterior midgut, hindgut), and a gut time course of blood meal digestion. Using Aegypti-Atlas, we provide insights into regionalization of gut function, blood feeding response, and immune defenses. We find that the anterior and posterior midgut possess digestive specializations which are preserved in the blood-fed state. Blood feeding initiates the sequential induction and repression/depletion of multiple cohorts of peptidases. With respect to defense, immune signaling components, but not recognition or effector molecules, show enrichment in ovaries. Basal expression of antimicrobial peptides is dominated by holotricin and gambicin, which are expressed in carcass and digestive tissues, respectively, in a mutually exclusive manner. In the midgut, gambicin and other effectors are almost exclusively expressed in the anterior regions, while the posterior midgut exhibits hallmarks of immune tolerance. Finally, in a cross-species comparison between Ae. aegypti and Anopheles gambiae midguts, we observe that regional digestive and immune specializations are conserved, indicating that our dataset may be broadly relevant to multiple mosquito species. We demonstrate that the expression of orthologous genes is highly correlated, with the exception of a ‘species signature’ comprising a few highly/disparately expressed genes. With this work, we show the potential of Aegypti-Atlas to unlock a more complete understanding of mosquito biology.
Acting as a Change Agent
Authors: Savaria Virginie , Jasmin Emmanuelle , Hudon Anne , Bédard Denis , Drolet Marie-Josée , Beaudoin Michaël , Jasmin Emmanuelle , Lavoie-Trudeau Étienne , Carrier Annie
Published: April 2022

Background: Acting as a change agent (CA) is a key role for Health and Social Services (HSS) professionals. It involves working collaboratively with actors across and outside the HSS system and influencing decision-makers. However, this role requires specific skills that HSS professionals generally feel that they have not mastered. The overarching goal of this research partnership is to explore the development of CA skills by HSS professionals using a customized training program.

Methods/Design: Through a research partnership, 128 HSS professionals will receive 7 hours of training using a professional co-development approach and a checklist. The immediate and medium-term effects of the training on their skills development will be evaluated with a self-administered questionnaire before and immediately following the training and again nine months later. The data will be analyzed using descriptive and inferential statistics.

Discussion: This study will shed light on the effects of a customized training program on CA skills development. It will also have three main benefits: (1) development of an easy-to-reuse CA training program and checklist; (2) partner’s ownership of these products through close involvement; and (3) development of a sustainable partnership between a team of researchers and a recognized organization with an extensive HSS network.
Bivalvos, organismos modelo en el biomonitoreo del riesgo ecotoxicológico de los antinflamatorios no esteroideos (AINE) para los ecosistemas acuáticos
Authors: Contreras-Almazo Illgner Ali Eddy , Gonzalez-Renteria Mariela
Published: April 2022

La creciente producción y consumo de productos farmacéuticos es un problema mundial, debido entre otros factores a la automedicación, malas medidas de eliminación en centros hospitalarios, aguas residuales de farmacéuticas, y la excreción animal y humana. Los antiinflamatorios no esteroideos (AINE) son considerados los fármacos más consumidos a nivel mundial y de libre venta. La falta de normas jurídicas que limiten los rangos de emisión en cuerpos de agua ha sido uno de los principales factores en el aumento de estos contaminantes emergentes (CE) en los ecosistemas acuáticos. Los estudios basados en el monitoreo de estos compuestos farmacéuticos nos permiten comprender todos los aspectos relacionados con el destino, concentración, distribución, efectos y alteraciones fisiológicas que causan en la biota acuática; por tal motivo, es necesario resaltar la importancia de los bivalvos como organismos modelo y bioindicadores. Esta revisión presenta una visión general de los estudios ecotoxicológicos que monitorean AINE, y evalúan las respuestas de algunas especies de bivalvos en programas de biomonitoreo y pruebas de toxicidad. Se ha reportado que los AINE en ambientes acuáticos pueden tener efectos negativos en bivalvos silvestres, además de provocar biomagnificación de los contaminantes. Con este estudio se espera propiciar el interés por la investigación científica en esta área poco explorada y necesaria para la farmacovigilancia y el monitoreo de los ecosistemas acuáticos
La flora de la ciudad de Madrid como modelo para la integración de la conservación de la biodiversidad en el diseño urbanístico
Authors: Domínguez Lozano Felipe , Sánchez de Dios Rut , Cabezas Fuentes Francisco José , Pías Couso Beatriz
Published: April 2022

La flora de las ciudades no ha sido objeto de demasiada atención conservacionista en el pasado. En este trabajo se ofrece un análisis de las posibilidades de conservación de la biodiversidad vegetal en el medio urbano valorando algunas herramientas desarrolladas por la Biología de la Conservación: áreas protegidas, reintroducciones, hábitats artificiales, arboricultura y jardinería. Después, se utiliza la flora de la ciudad de Madrid como posible modelo de aplicación de las medidas conservacionistas generales expuestas. Se mencionan algunas de las extinciones locales mejor documentadas en la ciudad y se propone el uso de distintos tipos de microrreservas (estratégicas, potenciales o de novo, y de extrarradio) para intentar evitar extinciones adicionales en el futuro. Se concluye con una propuesta novedosa de estrategia de gestión de la biodiversidad consistente en el encaje biótico dentro del planeamiento urbanístico general de las ciudades. El encaje biótico persigue, entre otros objetivos, incorporar a técnicos en biodiversidad en las plantillas locales de las ciudades para alcanzar una gestión más completa de las áreas verdes urbanas.
Efecto de la ingesta incidental de polietileno y polipropileno sobre el crecimiento de Oreochromis sp. manejada en condiciones de laboratorio
Authors: Ponce Mero Alisson , Chérrez Palma Bryan , Mero del Valle David
Published: April 2022

Actualmente la contaminación por microplásticos (MP) en los ecosistemas acuáticos se ha incrementado perjudicando la biota marina, siendo los ensayos ecotoxicológicos una herramienta para evaluar este impacto. El presente estudio estimó el efecto provocado por la ingesta de los MP polietileno (PE) y polipropileno (PP), en el crecimiento de juveniles de Oreochromis sp. Para cada tipo de MP se establecieron tres concentraciones (25%/75%, 50%/50% y 75%/25%) más un tratamiento control (sin MP), con tres réplicas distribuidas al azar constituidas por unidades experimentales de ocho juveniles de Oreochromis sp. (tamaño inicial 2 ± 0.5 cm). Se retiraron aleatoriamente dos individuos por cada tiempo de exposición (7, 14, 21 y 28 días) examinando los tractos digestivos de 154 peces en total. Los resultados no demostraron diferencias significativas en las variables de crecimiento en longitud (p=0.3444) y peso (p=0.0818) de Oreochromis sp. de los tratamientos experimentales, mientras que el índice de condición nutricional (K) tampoco demostró diferencias significativas (p=0.513) entre tratamientos, sin embargo, evidencian una tendencia de mayor condición nutricional en los tratamientos PE que PP. En el contenido de MP se hallaron diferencias significativas (p=0.6078) en el primer muestreo en los tratamientos experimentales, mostrando mayor presencia de PE respecto al PP en el tracto digestivo, probablemente debido a la retención y acumulación, diferencia de forma o tipo de polímero. Aunque la ingesta de MP no causaría efectos inmediatos en el crecimiento de Oreochromis sp. sus efectos podrían estimarse en estudios de mayor duración.
Efecto del sustrato en la propagación sexual de Cinchona officinalis L. (Rubiaceae)
Authors: Fernandez Franklin H. , Huaccha Annick E , Barturén Luci M , Quiñones Lenin , Sanchez Tito
Published: April 2022

Cinchona officinalis, conocida como árbol de la quina, es una especie emblemática de Perú, con alto valor medicinal, se popularizó por su uso antimalárico y se encuentra en peligro de extinción. El objetivo de la investigación fue estudiar el efecto del sustrato sobre la propagación sexual de C. officinalis. Se aplicó un diseño completamente al azar con cinco tratamientos de acuerdo con el tipo de sustrato T1 (25 % de tierra de bosque + 75 % de arena), T2 (50 % de tierra de bosque + 50 % de arena), T3 (75 % de tierra de bosque + 25 % de arena), T4 (100 % de tierra de bosque) y T5 (100 % de arena). En los tratamientos se emplearon tres repeticiones y 100 semillas por unidad experimental. El inicio de la germinación de C. officinalis ocurrió a partir de los 12 días después de la siembra hasta el día 42. El sustrato tierra de bosque tuvo mejor efecto en el índice (18.45 ± 3.63), velocidad (0.40 ± 0.06), tiempo (21.44 ± 0.98) y porcentaje de germinación (85 % ± 13.23 %); seguido por los tratamientos T3 y T2. Por su parte, T5 fue el tratamiento con menor efecto sobre la germinación de C. officinalis. El estudio evidencia que el tipo de sustrato empleado favoreció el proceso de germinación de semillas de C. officinalis; sugiriendo usar un sustrato procedente de bosques naturales y puro (sin combinación).
Changing urban bird diversity: how to manage adaptively our closest relation with wildlife
Authors: Díaz Mario , Ramos Anna , Concepción Elena D.
Published: April 2022

We human beings are becoming urban citizens. More and more people spend their lives in urban environments, so that the conservation and improvement of urban biodiversity is an increasingly hot topic. On the one hand, as cities grow bigger and more populated they can become more hostile for some birds, but cities can also be safer than the surrounding rural environment for others. On the other hand, factors affecting negatively or positively wild birds may also influence human’s health, either directly (e.g. pollution) or indirectly (enjoying wildlife diversity could contribute to improve our wellbeing). We review current state of knowledge on factors determining the abundance, diversity and health of urban birds, and derive methods for diagnosing what factors are acting in each particular case. Diagnoses are essential to design effective and efficient ways to manage urban bird diversity and improve it adaptively. We also address whether factors affecting birds could affect citizenship directly, so that urban birds can be used as indicators for healthy urban environments. Investigating and improving urban bird life can also improve human wellbeing through people’s involvement on citizen science programs. Monitoring approaches taken by both authorities and NGOs are still too general and badly designed, but collaboration among scientist, volunteers and authorities will contribute to make them effective. Improving citizen involvement will in turn contribute to improve urban bird diversity, closing a win-win loop for both people and wildlife wellbeing.
Comparison of Long-term Efficacy of Intravitreal Ranibizumab in Diabetic Retinopathy following Monthly vs Pro Re Nata vs Treat and Extend Protocol
Authors: Sarkar Avik Dey , Thakur Sanjay Kumar Daulat , Roy Rupam , Sarkar Ajoy Dey
Published: April 2022

Introduction: Diabetic Retinopathy (DR) is a major complication of Diabetes Mellitus (DM), which remains a leading cause of visual loss in working age populations. The most common cause of vision loss in patients with DR is Diabetic Macular Oedema (DME). Intravitreal administration of anti-Anti-Vascular Endothelial Growth Factor (anti-VEGF) agents is currently the mainstay of therapy for both early and advanced stages of DR. Aim: To compare long-term change in Central Macular Thickness (CMT) and Best Corrected Visual Acuity (BCVA) in patients with Non Proliferative Diabetic Retinopathy (NPDR) with Clinically Significant Macular Oedema (CSME) after receiving Intravitreal Ranibizumab (IVR) following monthly, Pro Re Nata (PRN) protocol and TreaT&Extend (T&E) protocol. Materials and Methods: This is a hospital based longitudinal prospective cohort study conducted on patients attending the Out Patient Department (OPD) of the Opthalmology Department at Midnapore Medical College & Hospital West Bengal, India. from October 2018 to February 2021. Institutional Ethical clearance was obtained prior to the initiation of the study. Among 93 patients, 31 were chosen each for IVR PRN Monthly (Group A), (Group B) and T&E protocol (Group C) over a period of nine months. CMT and BCVA were measured at baseline and followed up monthly for 12 months after last injection using Spectral Domain Optical Coherence Tomography (SD-OCT), while Glycated Haemoglobin (HbA1c) level was maintained below 7.4. Statistical analyses were performed using Statistical Package of Social Sciences (SPSS) statistics version 20 software. Chi-square test was used to find out the association between categorical variables. Pre and post comparisions were done using Wilcoxon sign rank test. A p-value less than 0.05 were considered as statistically significant. Results: There was significant decrease in CMT and betterment of BCVA in all groups at the end of treatment compared to baseline. At six months and one year of last injection there was no significant change in CMT in group A and C while group B at one year (p=0.0487) showed significant increase. There was no significant worsening of BCVA in group A and group C while group B (p=0.01) showed significant worsening at one year longterm follow-up. Conclusion: Thus, the present study concludes that, even though monthly protocol T&E protocol are equally good compared to PRN protocol on the basis of long-term beneficial effect, T&E protocol needed comparatively fewer doses of IVR compared to monthly protocol making it the choice of protocol for long-term control in NPDR with DME patients.
Extension Methods Used in the Implementation of the Swine Production and Dispersal Program in Calintaan, Occidental Mindoro Philippines
Authors: Declaro-Ruedas Mary Yole Apple , Francis A. Sy Dianne , Caballes Jr Joselito O. , Pradel Kent Abraham A.
Published: April 2022

This study was conducted to evaluate the extension modalities employed in the Swine Production and Dispersal Program (SPDP) implemented in Calintaan, Occidental Mindoro. It employed the survey research method. It was conducted at Barangay Malpalon and Poypoy, Calintaan, Occidental Mindoro. The respondents were the 30 randomly-selected Swine Production and Dispersal Program (SPDP) beneficiaries for at least one year and had received at least one piglet from the program. A survey and interview were conducted to determine whether the extension program has helped the beneficiaries. Mean, frequency distribution, percentage, and Kendal-Tau b were used in this study. The results shows that the SPDP beneficiaries were middle-aged, high school graduate, female, and member of the SPDP. The seminar is the “most employed” communication method used by the Tamaraw Conservation Program in disseminating information regarding swine production. The said program had contributed to the increase of the SPDP beneficiaries’ monthly income at the time of the implementation of the program. The “most frequent” problem encountered in the implementation of the SPDP is the additional expenses incurred by the household with regard to its operation.  Expenses had a significant relationship with the benefits and the problems encountered in SPDP. Further, expenses had a significant relationship with the benefits and the problems encountered in SPDP.
Influence of Biopolymer Synthesized from Tamarind Seed Polysaccharide (TSP) on Physiological and Biochemical Parameters of Maize Hybrid COH(M) 8 Seeds
Authors: Sivasakthi S. , Renganayaki P. R. , Sundareswaran S.
Published: April 2022

The experiment was conducted in Department of Seed Science and Technology, Tamil Nadu Agricultural University, Coimbatore, Tamil Nadu during 2021. Biopolymer was synthesized from Tamarind Seed Polysaccharide (TSP) and added with different additives and coated maize seeds to know how they effect their physiological and biochemical parameters. The seeds were given with four treatments viz., T0- control (untreated seed), T1- biopolymer (B.P) - 10g kg-1, T2- B.P (10g) + Humic acid (0.3g) + Zimmu (Allium cepa × Allium sativum) leaf extract (0.5 ml) and T3- T2+ Ascorbic acid (0.2 g) and evaluated for seed quality parameters. The results of the present investigation revealed that T3 was significantly superior viz., higher percentage of germination (95%), rate of germination (31.64), seed metabolic efficiency (2.78), seedling root length (25.92 cm), seedling shoot length (15.57 cm), total biomass production (9.41 g), vigour index I (3942), vigour Index-II (94.15). This treatment also recorded highest value of biochemical parameters such as α-amylase (2.23), dehydrogenase (1.87 OD value), catalase (29.94) and peroxidase (7.00) activities. It reduced the abnormal seedlings (2%), dead seeds (3%), days to 50% germination (2.54), mean emergence time (3.02) and pathogen infection (0.25%). We concluded that maize seeds coated with T3 had better seedling establishment and may be recommended as pre sowing seed treatment under organic agriculture.
Drug Therapy Problems Associated with Antibiotics Prescriptions in University of Uyo Health Centre, Uyo, Nigeria
Authors: Ajulo Olugbenga Matthew , Olorunsola Emmanuel Oluwatoyin , Osom Unwanna Akpan
Published: April 2022

Introduction: Antibiotic resistance has contributed as one of the greatest public health threats at present. This study aimed at identifying drug therapy problems (DTPs) associated with prescriptions of antibiotics to patients attending the University of Uyo Health Centre and presented a seminar as an intervention.

Method: A prospective observational study was carried out. One hundred (100) patient folders with 147 antibiotics prescriptions were used for the survey for the first-month collation of antibiotics prescriptions while one hundred and sixty (160) patient folders with 160 antibiotics prescriptions were used at the second -month of the survey. The seminar presentation on drug therapy problems associated with antibiotics prescriptions was held after the first -month of the survey. Data obtained were analyzed by using descriptive statistical tools such as frequency, mean, standard deviation and bar chart. The statistical analytical tool such as student T- test was used and significance was considered at p ≤ 0.05.

Result: The first survey involved 147 prescriptions of antibiotics. Prescriptions with DTPs were 77 (52.4%) while the most frequently occurring DTPs was drug interactions (37.1%), followed by inappropriate dosage frequency (23.7%) and unnecessary medication (22.7%). The follow up survey included 160 prescriptions of antibiotics, out of which 112 (70%) prescriptions of antibiotics contained 209 DTPs. The most frequent DTPs was drug interactions (49.3%), followed by inappropriate dosage duration (19.1%) and inappropriate dosage frequency (11.5%). The results also showed that antibiotics prescriptions with DTPs were significantly increased in the follow-up survey (p=0.00) of the study. Drug interaction (p=0.00), overdosing (p=0.00), underdosing (p=0.00) and Inappropriate dosage duration (p=0.00) were significantly increased in the follow-up survey.

Conclusion: This study had indicated prevalence of DTPs associated with antibiotic prescriptions. Drug interaction, inappropriate dosage frequency and unnecessary medication were very common among antibiotic prescriptions.
Molecular Characterization of Salmonella Typhimurium and E. coli O157:H7 Isolated from Ready-to-eat Chicken Meat
Authors: Ajulo Oluwatoyin Hephzibah , Adetunji Olusola Victoria , Ajulo Olugbenga Matthew
Published: April 2022

Background: Virulence genes are important in the pathogenesis of bacteria and in the mechanism of bacterial pathogenicity.

Objective: The study aimed at molecular detection of virulence genes such as sdiA, fimH, InvA and fliC and determination of similarity and links among the isolates.

Method: A total of 67 isolates including 4 controls were tested by Polymerase Chain Reaction (PCR) with 4 primer pairs including invA, fliC, sdiA and fimH to avoid bias. Full sequences of the 16S-Sequencing gene of both strains were carried out with 29 Salmonella and 30 E. coli isolates that were positive for amplification at 1500bp.ward hierarchical clustering model and agglomeration procedure was used. Clustered grouping and relational affinity test were conducted and depicted by the dendrogram. Molecular identification and interpretation were done using BLASTn Protocol.

Result: None of the isolates were positive to the invA or fliC gene fragments. One isolate from each of Salmonella Typhimurium and E. coli O157:H7 was positive to sdiA and fimH respectively. Three E. coli isolates were positive with an amplification of 500bp which is specific for fimH genes. One of the isolates E459 showed amplification of fimH gene with multidrug resistance to 5 drugs namely Ceftazidime, Cefuroxime, Augmentin, Nitrofurantoin and Ampicillin. Four Salmonella isolates had an amplification of 274bp specific for sdiA gene. Two variants of E. coli O157:H7 (unit g1 and unit g2) were identified. A mutant strain Salmonella Typhimurium LTS (STMD1) causing human gastroenteritis was identified also, Salmonella Typhimurium DT104 isolated exhibited multiple resistant genes (ACSSuT, SGI1) against several antibiotics. These are of public health significance.

Conclusion: This study has indicated presence of sdiA and fimH genes in Salmonella typhimurium and E. coli 0157:H7 respectively isolated from ready-to-eat chicken meats from public eateries. It also indicated association of sdiA and fimH genes with multi-drugs resistance.
Different Techniques used for Stump Closure in Laparoscopic Appendectomy
Authors: Shafaqat . , Hassan Syed Ashraf , Rashid Haris , Ali Mir Arsalan , Khan Fatima Zehra , Sidhwani Santosh Kumar
Published: April 2022

Background: The most prevalent surgical emergency for which patients present to the emergency room is acute appendicitis. Appendectomy is the surgical therapy for the problem, and it is one of the most common surgeries performed worldwide, with almost a quarter of all people (equally males and females) requiring one at some point in their lives. Methods that are used to close the stump in laparoscopic appendectomy include staplers, endo-loop, titanium clips, non-absorbable polymer clips (Hem-o-lock clips), hand-made loops, extracorporeal sliding knot, intra-corporeal ligation, ligature use or division with bipolar cautery.

Objective: To compare various methods of stumps closure in laparoscopic appendectomy.

Methods: This Double Blind – Randomized Quasi Experimental Trial was conducted upon a sample of 80 patients (selected using non-probability, consecutive sampling) in four  groups (G1: Endoloop, G2: Intracorporeal Knotting with Vicryl Size 2/0, G3: Extracorporeal Knotting with Chromic Catalent no Zero, G4: Vicryl Intracorporeal Trans fixation of Stump with 2/0 vicryl) of 20 each. Data was recorded onto a structured questionnaire containing inquiries pertaining to basic biodata, sociodemographic details, disease history, operative notes and post-operative follow-up. The data obtained was analyzed using SPSS 21.0 and MS. Excel.

Results:  The mean age of the sample stood at 43.96 (SD ± 16.9) years, with the age ranging from 17 to 80 years. Study more females were presented in all four groups. They have shown insignificant statistical association with p-value of 0.983. Post-operative complication in every group was recorded as post-operative hemorrhage, knot slippage, abscess and surgical site infection. Overall in 9 (11.3%) of patients experienced different post-operative complications showed insignificant statistical association with the p-value of 0.945.

Conclusion: In current study we concluded that endoloop is the most efficient and less time consuming procedure used for the stump closure in the patient undergo laparoscopic appendectomy. Intra operative time taken is also less compared to other groups. Less number of intra-operative and post-operative complication were noted in the endoloop group. Hospital stay is also observed to be less in the endoloop group.
Examine the Vitamin-D Status of HCV-Infected Patients and Control in Lahore, Pakistan
Authors: Abbas Muhammad , Ghani Hafiz Usman , Rauf Huda , Zulfiqar Saba , Usman Muhammad , Rehman Abdul
Published: April 2022

Introduction: Hepatitis C virus is a serious health issue that can remain fatal owing to their dire repercussions. HCV causes approximately 710,500 deaths each year, has over 190 million individuals affected

Objective: Serum Vitamin-D has an important part in inflammatory and infections illnesses, particularly liver diseases. The purpose of this experiment was to examine the Vitamin-D status of HCV-diseased cases and control in Lahore, Pakistan.

Methods: From the 25th of August, 2019 to the 25th of February, 2020, we conducted randomized cross-sectional research on 78 people at Services Hospital in Lahore. Fifty-one individuals tested positive for hepatitis C RNA-PCR (25 salaried cirrhotic and 25 decompensated cirrhotic cases). In addition, 24 healthy controls were selected who did not have liver problems. ARTUS ® HCV QS-RGQ V1 was used to perform HCV RNA–PCR. Chemiluminescence was used to determine vitamin D levels. For descriptive statistics, SPSS version 20 was employed.

Results: When compared to untreated (32.43 ng/mL), average level of Vitamin-D in Treated patients remained considerably inferior in supplied and fluid resuscitation hepatocellular carcinoma (28.88 ng/mL & 21.67 ng/mL, respectively). In this research, 78.6 percent of HCV patients had suboptimal Vitamin-D levels. Vitamin-D deficiency (22-28 ng/mL) was seen in both healthy people (46.9 percent) and HCV sufferers (38.3 percent) (P 0.002). Furthermore, Vitamin-D levels were shown to have an inverse association with more multi - organ failure, having 56.3 percent of respiratory failure cirrhosis people undergoing from Vitamin-D insufficiency, relative to 14.7 percent in the recovered cirrhotic groups (P 0.0002).

Conclusion: Suboptimal levels of Vitamin-D (inadequacy before lack) remain more common in hepatitis C comparison to well controls. Vitamin-D insufficiency were found to be directly related to somatic symptoms.