bluuebunny/crossref_metadata_2025 huggingface dataset:
On methodological approaches to the improvement of surface water bodies and target indicators of the natural waters’ quality
Authors:   Transbaikal State University, Zaslonovsky V. , Sharapov N. ,   Transbaikal State University, Bosov M. ,   Transbaikal State University
Published: April 2021

The paper is devoted to the development of proposals concerning the improvement of surface water bodies and the appointment of target indicators of the natural waters’ quality. The paper considers a variety of problems of preserving, restoring and improving the quality of natural surface waters: from regional features of the formation of natural water composition, to differences in the requirements for the quality of water consumed. The object of the study is the qualitative indicators of the waters of natural water bodies, and the subject of the study is the methodological approaches to the normalization of these indicators. The purpose of the work is to identify the main shortcomings in the domestic system of rationing the quality of natural waters, and to form appropriate proposals. For this purpose, the following tasks were set and solved: to review the methodological approaches to assessing and rationing the quality of natural waters used in some foreign countries and in the Russian Federation, to identify the main causes and shortcomings; to make proposals for improving the current system of water quality rationing. The result of this work is the conclusions about the lack of impact of the strategy operating in Russia in the development of schemes of complex use and protection of water objects, standards of permissible impact on water bodies, the appointment of permissible discharge limits in terms of maintaining and improving the water quality of natural water bodies. The reasons that led to this are indicated. The necessity of taking into account, in addition to the physical and chemical composition, also hydrobiological parameters is shown. It is concluded that instead of fisheries management standards, environmental standards should serve as the basis for target indicators of water quality of natural water bodies, which determine the well-being of humans and the stable functioning of aquatic ecosystems, taking into account regional factors. Proposals were made to adjust the methodological approaches to the implementation of this strategy. According to the authors, these proposals will speed up the solution of the main objectives of the strategy – the ecological improvement of water bodies, the preservation of unique aquatic ecosystems and the environmentally safe development of territories that previously experienced relatively small anthropogenic impacts (Eastern Siberia and the Far East)
REGIONAL SECURITY STUDIES IN MODERN FEDERAL STATE EDUCATIONS: GOVERNMENT AND REGIONAL DISCOURSES
Authors:   Transbaikal State University, Romanova N. , Kononov S. ,   Far Eastern Higher Combined Arms Command School named after Marshal of the Soviet Union K.K. Rokossovsky, Shevchenko M. ,   Transbaikal State University, Shevchenko Yu. ,   Transbaikal State University
Published: April 2021

The purpose of the paper is to study the problem of regional security, for which the most urgent is the problem of powers distribution between the central government and the regions. The aim of the paper is to compare the ideas about the essence of regional security in the discourse of state power and the regions in order to find a solution to the possibility of managing the situation of regional security. The research methodology involves the use of comparative analysis, as well as the use of a phenomenological and situational approach, the theory of social services and the dialogue of cultures. The authors argue that the solution of the regional security problem within the framework of the federal state is a continuous process of finding a compromise aimed at an attempt to meet the multidirectional needs, one of which is to ensure the unity, sovereignty and integrity of the Russian Federation; the other is to protect and safeguard the safe existence of regions. Therefore, it is necessary to state that the system of vital interests at the regional level is mobile; it changes under the influence of conditions, security environment. A decisive role in the process of changes in regional interests, and, consequently, regional security, is played by factors prompting the region to take fundamentally important political and other actions, among which discourses of regional security stand out, such as the discourse of state power and regional discourse of security. This orientation determines the novelty of the study, which for the first time is aimed at separating the regional security discourse from the security discourse of state power and substantiating the resolution of the contradiction between them. As a result, the paper examines a regional security model within the framework of the concept of regional security complexes, which offers an analysis of this problem through a critical comparison of the power and regional discourses that have an intellectual impact on the formation of the foreign and domestic political situation in the country at various moments of political reality
Serologic problems associated with administration of intravenous immune globulin (IVIg)
Authors: Branch D.R.
Published: April 2021

Intravenous immune globulin (IVIg) is manufactured from large pools of donor plasma and contains a high diversity of antibodies, primarily IgG. For this reason, IVIg is routinely used as antibody replacement therapy for patients having primary immunodeficiencies. In 1981, IVIg was also found to be a strong immunomodulator of various inflammatory and autoimmune conditions. This observation has led to the exponential increase in the use of IVIg throughout the world, with the United States and Canada being the biggest users of IVIg. Although relatively rare, adverse events, such as hemolytic anemia and thrombosis, can complicate the administration of IVIg. More frequently, the administration of IVIg can cause serologic challenges for the transfusion service including ABO discrepancies, positive direct antiglobulin tests, positive antibody detection tests, and incompatible crossmatches. This article will review each of the potential transfusion service challenges associated with IVIg administration.
Effect of structural water on the elasticity of orthopyroxene
Authors: Hou Mingqiang , Zhou Wen-Yi , Hao Ming , Hua Florian Tian-Siang , Kung Jennifer , Zhang Dongzhou , Dera Przemyslaw K. , Zhang Jin S.
Published: April 2021

As a major nominally anhydrous mineral (NAM) in the Earth’s upper mantle, orthopyroxene could host up to several hundred parts per million H2O in its crystal structure and transport the H2O to the deep Earth. To study the effect of structural H2O on the elasticity of orthopyroxene, we have measured the single-crystal elasticity of Mg1.991Al0.065Si1.951O6 with 842–900 ppm H2O and 1.64 ± 0.20 wt% Al2O3 at ambient conditions using Brillouin spectroscopy. The best-fit single-crystal elastic moduli (Cijs), bulk (KS0), and shear (G0) modulus of the hydrous Al-bearing orthopyroxene were determined as: C11 = 235(2) GPa, C22 = 173(2) GPa, C33 = 222(2) GPa, C44 = 86(1) GPa, C55 = 82(1) GPa, C66 = 82(1) GPa, C12 = 75(3) GPa, C13 = 67(2) GPa, and C23 = 49(2) GPa, KS0 = 111(2) GPa, and G0 = 78(1) GPa. Systematic analysis based on the results presented in this and previous studies suggests that the incorporation of 842–900 ppm H2O would increase C13 by 12.0(7)% and decrease C23 by 8.6(8)%. The effects on C11, C22, C33, C44, C66, KS0, and VP are subtle if not negligible when considering the uncertainties. The C55, C12, G0, and VS are not affected by the presence of structural H2O. Although laboratory experiments show that Fe,Al-bearing orthopyroxenes can host up to 0.8 wt% H2O in its structure, future high-pressure-temperature elasticity measurements on orthopyroxene with higher H2O content are needed to help better quantify this effect.
A new high-pressure experimental apparatus to study magmatic processes at precisely controlled redox conditions
Authors: Alex Alice , Zajacz Zoltán
Published: April 2021

Oxygen fugacity (fO2) is typically controlled in high P-T experiments by using solid-state redox buffer assemblages. However, these are restricted to impose discrete fO2 values, often with significant gaps between neighboring assemblages. Semi-permeable hydrogen membranes (Shaw 1963) are often used in internally heated pressure vessels for more flexible fO2 control in hydrous experiments; however, their implementation in more widely available externally heated pressure vessels has not yet gained space. We propose a prototype molybdenum-hafnium carbide (MHC) pressure vessel apparatus that simultaneously allows rapid quenching and flexible, precise, and accurate redox control via a custom-designed hydrogen membrane. Test runs with two membranes at a time, one imposing and another one monitoring fH2, demonstrated that 95% of the imposed hydrogen pressure was attained inside the pressure vessel within 2 h at 800–1000 °C, after which a steady state equilibrium was established. Furthermore, experiments comparing redox-dependent Cu solubility in silicate melts at fO2 imposed by the fayalite-magnetite-quartz, Re-ReO2, and MnO-Mn2O3 buffers and identical target fO2 imposed by the hydrogen membrane confirmed consistency between the two methods within 0.25 log units fO2 deviation at T = 900 °C and P = 2000 bar. This powerful yet cost-effective and low-maintenance apparatus may open up new pathways for studying redox reactions in hydrous magmas and magmatic fluids. As a proof of concept, we conducted near-liquidus phase-equilibrium experiments with H2O-saturated calc-alkaline basalt and shoshonite melt compositions at five different fO2 values equally distributed between half log unit below the Ni-NiO buffer (NNO-0.5) and NNO+2.7. Most experiments crystallized olivine, clinopyroxene, and Ti-magnetite. The Mg# of the olivine increased with fO2, and the Fe3+/Fetotal ratios in the silicate melt were determined based on Fe(II)-Mg exchange between olivine and melt. The Fe3+/Fetotal ratios in the shoshonite melt were systematically higher by about 0.06 ± 0.01 than those in the calc alkaline basalt melt at identical fO2. The values determined for the basaltic melt were consistent within 1σ error (<0.033 deviation) from those predicted by the equation of Kress and Carmichael (1991). The Fe-Ti exchange coefficient between magnetite and silicate melt increases from 1.73 ± 0.19 (1σ) at NNO –0.5 to +7.12 ± 0.36 at NNO+2.7 for shoshonite and has a similar range for the calc-alkaline basalt.
OUR INSTIUTIONAL EXPERIENCE IN VISCERAL ARTERY ANEURYSMS
Authors: a Srinivasan , Kumar Prathap , a Velladuraichi , Kumar Ilaya , b Sritharan
Published: April 2021

Objectives: To evaluate the incidence, management, and outcome of visceral artery aneurysms (VAA) over the 5. years in our institution, a tertiary care centre, Madras Medical College. Methods 14 patients with 19 VAA were analysed according to location, diameter, aneurysm type, aetiology, rupture, management, and outcome. Results: VAA were localised at the splenic artery, coeliac trunk, renal artery, hepatic artery, superior mesenteric artery, and other locations. The aetiology was mostly degenerative, connective tissue disease. The rate of rupture was higher in pseudo-aneurysms than true aneurysms (66% vs 5%). 18 VAA were treated by intervention {coil embolisation} (n=3) or surgery (n=9) or hybrid [n=1] and one patient was managed conservatively. Three cases with ruptured VAA were treated on an emergency basis. The largest aneurysm was about 16cm and smallest one was about 1mm . After interventional treatment, the 30-day mortality was 21.4 % in ruptured VAA compared to no mortality in non-ruptured cases. Follow-up included USG and/or CT after a mean period of 7 months. The current status of the patient was obtained by a structured telephone survey. Conclusions: There is increase incidence of Celiac and SMA aneurysms. Aneurysm size seems to be a reliable predictor for rupture. Young patient need vasculitic workup for further management.
HYDATIDOSE PELVIENNE : A PROPOS DE DEUX CAS
Authors:   Service De Gynecologie-Obstetrique I, CHU Hassan II, Fes, Maroc., Mohamed Zeine N. , Mohamed Lemine M ,   Service De Gynecologie-Obstetrique I, CHU Hassan II, Fes, Maroc., Lemrabott E. ,   Service De Gynecologie-Obstetrique I, CHU Hassan II, Fes, Maroc., Karame S. ,   Service De Gynecologie-Obstetrique I, CHU Hassan II, Fes, Maroc., Mamouni N. ,   Service De Gynecologie-Obstetrique I, CHU Hassan II, Fes, Maroc., Errarhay S. ,   Service De Gynecologie-Obstetrique I, CHU Hassan II, Fes, Maroc., Bouchikhi C. ,   Service De Gynecologie-Obstetrique I, CHU Hassan II, Fes, Maroc., Banani A. ,   Service De Gynecologie-Obstetrique I, CHU Hassan II, Fes, Maroc.
Published: April 2021

Introduction: Lhydatidose sevit a letat endemique au Maroc, sa localisation pelvi genitale est rare et trompeuse. Elle est due au developpement chez lHomme de larves de cestodes du genre Echinococcusgranulosus. Patientes et methodes: Nous rapportons les cas des deuxpatientes operees pour des masses abdominopelvienne avec decouverte per operatoire des kystesperitoneales dont lanapath en faveur dhydatidosepelvien. Discussion : La localisationpelviennedu kyste hydatique est rare. Elle varie entre 0,30 % et 4,27 % des localisations hydatiques selon les auteurs.Le mode de contamination hydatique de la region pelvienne demeure hypothetique la contamination est habituellement secondaire a la rupture intra-abdominale dun kyste hydatique hepatique. La symptomatologie peut etre vague et deroutante, telle que desmetrorragies ou une sterilite. Le diagnostic peut etre pose fortuitement lors de la cesarienne ou lors dune grossesse compliquee, un travail dystocique ou une hemorragie des suites de couche. Le traitement des kystes hydatiques est chirurgical. La voie dabord doit etre large, la sterilisation du kyste et la protection des champs operatoires est assuree par des solutions scolicides leau oxygenee est la plus utilisee. Il est recommande de faire une kystectomie ou une peri-kystectomie des kystes accessibles et sans danger et une kystectomie partielle pour les kystes profonds et au contact avec leselements vasculaires. Le traitement medical est peu efficace il est indique en cas de contre-indication operatoire ou en cas de localisations multiples ou si la resection est incomplete. Conclusion: Bien que rare, le diagnostic de kyste hydatique pelvien doit etre evoque devant toute malade presentant une masseabdominopelvienne. La kystectomie est le traitement de choix. Le traitement medical peut etre utilise en deuxieme intention.
DETERMINANT OF PERFORMANCE OF STEEL INDUSTRY SUPERVISORS IN INDONESIA
Authors:   University of Al-Khairiyah Indonesia., Rustandi Tata
Published: April 2021

The purpose of this study was to develop the determination of training factors, Job Satisfaction, Organizational Culture, Work Motivation, and Emotional Intelligence (EQ) on Supervisor Performance in the steel industry in PT. Krakatau Steel and PT. Pindad. The design of this study is Ex-Post Facto which uses causal analysis that explains the relationship between variables and the number of samples of 200 people selected through convinience sampling samples. The data collection method uses questionnairesand processed using SPPS applications and Lisrel applications to process and analyze Structural Equation Modeling data. Descriptive research results state that respondents assessment of Training, Job Satisfaction, Organizational Culture, Work Motivation, Emotional Intelligence (EQ) and Supervisor Performance has been relatively good. The results of causality research that received hypotheses are: 1) Training affects Job Satisfaction and 2) Work Motivation affects Job Satisfaction. The results of causality studies that reject hypotheses and become novelty of this study are: 1) Training has no effect on Work Motivation 2) Training has no effect on Performance 3) Emotional Intelligence has no effect on Performance 4) Emotional Intelligence has no effect on Job Satisfaction 5) Emotional Intelligence has no effect on Work Motivation 6) Organizational Culture has no effect on Work Motivation 7) Organizational Culture has no effect on Job Satisfaction 8) Organizational Culture has no effect on Performance 9) Work Motivation has no effect on Performance and 10) Job Satisfaction has no effect on Performance.
FEASIBILITY STUDY FOR THE USE OF NATURAL MORDENITE IN PURIFICATION PROCESSES OF WASTEWATERS FROM PHARMACEUTICAL POLLUTANTS
Authors:   Iv.Javakhishvili Tbilisi State University P.Melikishvili Institute of Physical and Organic Chemistry., Eprikashvili L.G. , Kordzakhia T.N. ,   Iv.Javakhishvili Tbilisi State University P.Melikishvili Institute of Physical and Organic Chemistry., Zautashvili M.G. ,   Iv.Javakhishvili Tbilisi State University P.Melikishvili Institute of Physical and Organic Chemistry., Rubashvili I.M. ,   Iv.Javakhishvili Tbilisi State University P.Melikishvili Institute of Physical and Organic Chemistry., Pirtskhalava N.V. ,   Iv.Javakhishvili Tbilisi State University P.Melikishvili Institute of Physical and Organic Chemistry., Dzagania M.A. ,   Iv.Javakhishvili Tbilisi State University P.Melikishvili Institute of Physical and Organic Chemistry., Tsintskaladze G.P. ,   Iv.Javakhishvili Tbilisi State University P.Melikishvili Institute of Physical and Organic Chemistry.
Published: April 2021

The present research concerns the possibility of adsorptive removal of the frequently used antibiotics Ã¢Â€Â“ moxifloxacin and norfloxacin on natural zeolites Ã¢Â€Â“ mordenite and its acid-modified form from aqueous solutions. The adsorption of the above-mentioned antibiotics on the selected natural zeolite samples was investigated under static and dynamic conditions. Adsorption experiment under dynamic conditions carried out using the specially constructed dynamic type of laboratory equipment. Based on the data of chemical, IR spectroscopic, X-ray diffraction analyses, it has shown that when the zeolite adsorbent is treated with an acid, an equivalent exchange of extra framework cations for a hydrogen ion and dealumination occurs and silanol groups are formed at the same time. The increase in the adsorption activity of mordenite as a result of its treatment with acid is associated with an increase in the pore size due to the unblocking of the adsorbent aluminosilicate framework channels during dealumination.
NATURAL DISASTER PREPAREDNESS OF MACALAYA NATIONAL HIGH SCHOOL, CASTILLA, SORSOGONAN ASSESSMENT
Authors: A. Santonia JR. Pedro
Published: April 2021

This research aimed to determine the preparedness of the students of Macalaya National High School in Castilla, Sorsogon to natural disasters for the school year 2019-2020.The descriptive research was used in the study using the one hundred eighty students of Macalaya National High School as the respondents. A self-made questionnaire and rubrics to describe the level of preparedness. Mean and standard deviation and Pearson r correlation using an alpha level of .05 were used as the statistical tools.The study revealed the following findings. The students of Macalaya National High School preparedness to natural disaster like typhoon has an overall mean of 4.62 and has a standard deviation of 0.626 with a variance of 0.3924 was rated as Very Great Extent. Landslide has an overall mean of 4.63 and has a standard deviation of 0.617 with a variance of 0.3813 was rated as Very Great Extent. Storm surge has an overall mean of 4.61 and has a standard deviation of 0.632 with a variance of 0.3992 was rated as Very Great Extent. Earthquake has an overall mean of 4.62 and has a standard deviation of 0.630 with a variance of 0.3976 was rated as Very Great Extent. The findings show that there is a significant correlation between the level of natural disaster and disaster preparedness of the students of Macalaya National High School at 0.05 level of significance. It shows that the null hypothesis stating that There is no significant correlation between the level of natural disaster and disaster preparedness of the students of Macalaya National High School is rejected. Thus, the alternative hypothesis is accepted. It inferred that there is a significant correlation between them.It was recommended that the School Disaster Risk Reduction Management Council must sustain the preparedness of the school. Constant reminders and promotions about preparedness against natural disaster is a must. Also, training and seminars must be included in the inset of the teachers with the special participation of the students governing council.
STUDENT ATTITUDES AND BEST PRACTICES ON SCIENCE PERFORMANCE-BASED ASSESSMENT
Authors:   Pasig City Science High School, Pasig City, Manila, Philippines., M. Villacrusis Ephraim
Published: April 2021

Performance â€“based science assessments provide students with valuable experiences and opportunities to improve students learning. Understanding the attitude of both teachers and students is an important aspect to design suitable performance-based assessment to ensure quality science education. Thus, this study was crafted to determine the teachers and students attitude towards performance-based science assessment and best practices of teachers. This descriptive survey explored the attitude of teachers and students about performance â€“ based assessment. While, Mann-Whitney U test was used to analyzed the significant difference between the teachers and students attitude towards science performance â€“ based assessment. Findings, suggest that students viewed the test performance positively in terms of grading the students fairly in getting good marks in science. While science teachers, believe that class presentations provide opportunities for students, to demonstrate their ability and knowledge during science discussion. Mann-Whitney U test indicates a mismatched between the teachers and students attitude on the performance-based science assessments. While, best practices of science teachers on science performance â€“based assessment are focused on student-centered activities such as simulation, student journals, exhibits, debates, community based project, project based learning, presentation of science investigatory project, and open-ended questions. Thus, it is necessary for the schools to strengthens the teachers professional development especially in the development and innovations of effective science performance-based assessment tool in order to increase learners achievement. It is also necessary to strengthens students understanding about the role and importance of the different science performance task implored by the teacher.
BENEFICIAL EFFECTS OF PROBIOTICS BASED THERAPY FOR IMMUNE HOMEOSTASIS
Authors:   Department of Biotechnology, KoneruLakshmaiah Education Foundation, Guntur, Andhra Pradesh, India., Chadalavada Supriya , Raman Gurumanchi Sri ,   Department of Biotechnology, KoneruLakshmaiah Education Foundation, Guntur, Andhra Pradesh, India., Mannam Bhuvaneswari ,   Department of Biotechnology, KoneruLakshmaiah Education Foundation, Guntur, Andhra Pradesh, India., Naga Raja Kumari Nagalingam Bala ,   Department of Biotechnology, KoneruLakshmaiah Education Foundation, Guntur, Andhra Pradesh, India., Veeravilli Suryanarayana ,   Department of Humanities and Basic Sciences, Aditya Engineering College, Surampalem, Andhra Pradesh, India.
Published: April 2021

Several approaches have been used to demonstrate that signals derived from gut microbiota are critical for the development of the immune system. Probiotics are live microorganisms that have beneficial effects on host health, including extended lifespan, when they are administered or present in adequate quantities. However, the mechanisms by which probiotics stimulate host longevity remain unclear and very poorly understood. Probiotic supplements are needed to determine the effectiveness as a non-chemical approach to promote health and welfare. Our studies focus on the assessment of the molecular impact of probiotic administration involved in homeostasis and immunity. Shrimps received the recommended doses of microbial pack containing Bacillus species andRhodococcus species. The fermentation was carried at 37Â°C for 72 hours under microaerophilic condition. The parameters like pH, microbial load, acidity and concentration of reducing sugar had been measured.This probiotic pack when used either alone or in combination with traditional dairy starter, significantly improved the nutritional properties and the shelf life of the product. The present work will be valuable to elaborate novel functional food based on these original probiotic properties.
DATABASE DESIGN FOR COSPLAY MAKING SERVICE OUTLET SELECTION RECOMMENDATION SYSTEMS
Authors:   Faculty of Engineering, Computer Science Program, Universitas Satya Negara Indonesia., Bahat Nauli Sukarno , Panjaitan Bosar ,   Faculty of Engineering, Computer Science Program, Universitas Satya Negara Indonesia.
Published: April 2021

This research is a type of action research. Aims to design a database for a costume ordering service outlet recommendation system. The application is built using the flutter framework as the user interface, the PHP language as a data processor that is sent from the application and MySQL as the database.A recommendation system is a system that is able to identify and provide high potential content selected by users based on filtering information that takes preferences from user behavior and history.The final result of the database design shows that the database design consists of 5 tables, namely the User Table, the Orderuser Table, the Outlet Table, the Rating Table, and the Review Table, as well as the Web-based Cosplay Making Service Outlet Selection Recommendation System.
Sobre médicos, piaches y teguas: Una historia particular de la persecución, expropiación y transculturación de la medicina prehispánica en el Virreinato Del Nuevo Reino de Granada durante la conquista y la colonia
Authors: Guerrero Romero Jarol Esmyt
Published: April 2021

Los procesos que se llevaron a cabo luego del contacto de los pueblos originarios con el conquistador español, en términos de saberes médicos en el territorio conocido como Virreinato de Nueva Granada, influyeron en las relaciones de conquistador-conquistado en procesos como la estigmatización y persecución de saberes ancestrales, las diversas formas de transculturación y el proceso de expropiación de algunos elementos de la cultura prehispánica.
Conocimiento de los empresarios de Villanueva Casanare sobre la Ley Zomac
Authors: Lozano Lozano Janeth , Saavedra Orozco Yuli Andrea
Published: April 2021

La normatividad colombiana plantea que las nuevas sociedades que desarrollen todo el proceso productivo en los municipios denominados Zonas más Afectadas por el Conflicto Armado (Zomac) tendrán beneficios tributarios durante 10 años, consistentes en tarifa progresiva del impuesto de renta a partir del 2017, que varía según el tamaño de la empresa que se obliga a cumplir con requisitos mínimos de inversión y generación de empleo o al pago parcial del impuesto de renta mediante la inversión directa en ejecución de proyectos de trascendencia social en las Zomac al obtener ingresos brutos iguales o superiores a treinta y tres mil seiscientos diez (33.610) unidades de valor tributario (UVT). Se realizó un estudio de tipo descriptivo con enfoque mixto (cuantitativo-cualitativo) para la caracterización de los empresarios, determinar el conocimiento y nivel de acogimiento a la normatividad, aplicándose un cuestionario a los empresarios y una entrevista semiestructurada a personal de los entes municipales y gubernamentales sobre el conocimiento y divulgación sobre lo reglamentado por la ley para las Zomac, permitiendo esclarecer la realidad en la aplicación normativa que plantea incentivos tributarios para cerrar las brechas de desigualdad socioeconómica en las Zomac.
El impacto de la formación profesional de la Facultad de Educación en la Seccional Oriente de la Universidad de Antioquia
Authors: Brand Monsalve Edinson Gabriel , Castañeda Pareja Izzmay Nemessis
Published: April 2021

La descentralización educativa, proyectada mediante la oferta localizada y pertinente al territorio, cuenta con poca información respecto al impacto que se ha logrado después de tres décadas de presencia de la universidad en la región del Oriente Antioqueño. Este artículo presenta los resultados del estudio realizado con 91 egresados de la Facultad de Educación, el cual valoró las transformaciones que la educación superior generó en sus trayectorias de vida y, a través de estas experiencias, en los territorios a los que pertenecen, encontrando que se favoreció significativamente la acumulación de capitales para el desarrollo de los sujetos y el territorio.
Functional activity of the endothelium and immune status in atherosclerotic lesions of the aorto-iliac segment and revascularization
Authors: Lazarenko Viktor A. , Bobrovskaya Elena A. , Mishustin Vladimir N. , Mezentseva Anna V. , Petrova Arina A.
Published: April 2021

Objective. The aim of the study is the evaluation of endothelial functional activity and immune status in systemic and local blood flow in atherosclerotic lesions of the aorto-iliac segment after open and endovascular interventions and establishing the relationship with the lesion class. Materials and methods. The study included 190 patients with lesions of the aorto-iliac segment. Depending on the type of surgical intervention, patients were divided into two groups: group I (n=97) - patients who underwent aorto-femoral bypass surgery, group II (n=93) - patients who underwent TRANS-balloon angioplasty with stenting of the iliac arteries. Results. Violations of the functional state of the endothelium and the immune status in the systemic and local blood flow, which do not correlate with the TASC II lesion class (TransAtlantic Inter-Society Consensus II), were revealed. There were differences in the factors of endothelial damage (in patients of group II before surgery, the level of homocysteine in the systemic blood flow, oxidized low-density lipoproteins in the systemic and local blood flow), hemostatic form of endothelial dysfunction (in group I, inhibitor of tissue plasminogen activator type I (PAI-1) in the systemic and tissue plasminogen activator (t-PA) in the local blood flow) and apoptosis (higher in group I in the systemic and local blood flow). During revascularization of the aorto-iliac segment, there were violations of the hemostatic form of endothelial dysfunction in group II with an increase in PAI-1 by 14.8% (p<0.001) in the systemic blood flow and by 1.9 times (p<0.001) in the revascularized arterial segment compared to group I. In group II after revascularization was significantly higher the immunoglobulins (Ig) class A in system and the circulating immune complexes, interleukins 1 (IL-1) in local blood flow and lower levels of IgM, interleukins 6 (IL-6), IL-1 in system and IgA, IgM, IL-6 in local blood flow compared with I group. Conclusion. The study of the features of the functional state of the endothelium and the immune status will optimize the management strategies of patients after various types of revascularization interventions on the aorto-iliac segment.
Features of psychological status in acute myocardial infarction in women and men
Authors: Nikolaeva Tatiana O. , Anikin Viktor V. , Izvarina Olga A. , Sedova Anna A.
Published: April 2021

Changes in psychological status undoubtedly have a great impact on the development and course of myocardial infarction (MI). Objective - to study changes in the psychological status in women with acute myocardial infarction (AMI) in comparison with male patients and the reflection of these changes on the quality of life. Materials and methods. A single-stage observational study was performed in the city hospitals of Tver. 120 women with AMI aged 36-74 years and 50 men with AMI aged 37-72 were examined. The main group (women with AMI) was divided into two subgroups: the first - patients under 60 years of age, the second - 60 years and older. The study of psychological characteristics of the individual was carried out using the abbreviated multifactor questionnaire for personality research (the so called “Mini-Mult” or “SMOL”), the personality questionnaire of the Bekhterev Institute (the so called “LOBI”), and the methodology for assessing the quality of life of a patient (QOL) according to V.P. Zaitsev. Results. In women aged 60 years and older, an increase in the profile of pitches on all scales was detected. The most noticeable increase in indicators was observed on the scales of the neurotic triad (1st, 2nd, and 3rd) and the 6th Mini-Mult scale. Analysis of the LOBI test revealed that the level of anxiety, hypochondriac, sensitive, neurasthenic, dysphoric and melancholic types of attitude to the disease prevailed in women, with the greatest severity of changes in the group of women under 60 years of age. In the block of interpsychic orientation, the most significant increase was in the sensitive type of attitude to the disease, which prevailed in both groups of women compared to men. The total indicator of "quality of life" was reduced in all the examined groups, and this decrease was most pronounced in older women. Conclusion. Women with AMI have more pronounced changes in their personal and emotional status than men. This is manifested in an increase in hypochondriac, depressive, emotionally labile symptoms; anxiety, hypochondriac, neurasthenic types of response to the disease and a decrease in the "quality of life".
Dimensiones pedagógicas para el uso de internet en la educación telesecundaria
Authors: Ramón Rocío , Edel-Navarro Rubén , Figueroa-Rodríguez Sebastián
Published: April 2021

Se presentan los avances de una investigación doctoral, la cual tiene como objetivo caracterizar las competencias de los docentes para el uso pedagógico de internet en las telesecundarias del municipio de Veracruz, en México. Se aborda desde un enfoque cualitativo, a través de un estudio de caso múltiple, de alcance descriptivo, con elementos de corte etnográfico y hermenéutico. Se realizaron entrevistas a profundidad con 5 docentes, seleccionados con la técnica no probabilística intencional. Los hallazgos obtenidos con el método de análisis del discurso, muestran evidencia de que los docentes incorporan internet en sus estrategias didácticas, contemplando como la práctica más común, la proyección de videos en YouTube para reforzar los contenidos del programa; sin embargo, consideran que su empleo pedagógico les demanda el desarrollo de destrezas docentes asociadas con la disposición, planeación de actividades, actualización permanente sobre herramientas digitales y conocer el marco jurídico para su incorporación en el aula.
Processos formativos de professores supervisores no âmbito do PIBID: sentidos atribuídos às atividades experienciadas na universidade e na escola
Authors: Oliveira Sandra Alves de , Rezende Dayselane Pimenta Lopes , Carneiro Reginaldo Fernando
Published: April 2021

Este artigo tem como objetivo compreender os sentidos atribuídos pelos professores supervisores do Programa Institucional de Bolsa de Iniciação à Docência (Pibid) às atividades experienciadas na universidade e nas escolas parceiras no âmbito do subprojeto Laboratório de Práticas Pedagógicas. Procurou-se, por meio de um estudo analítico-descritivo, analisar e discutir dados dos relatórios produzidos pelos oito professores supervisores participantes do subprojeto do Pibid, no período de 2014 a 2017, em parceria com estudantes bolsistas de Iniciação à Docência (ID), as professoras formadoras coordenadoras de área do Departamento de Educação da Universidade do Estado da Bahia e os professores coformadores das quatro escolas da educação básica da rede municipal de ensino de Guanambi, estado da Bahia, que participaram deste programa. A análise dos dados indica que as atividades desenvolvidas pelos professores supervisores na universidade e nas escolas parceiras do subprojeto Laboratório de Práticas Pedagógicas, por meio da participação nos grupos colaborativos de estudo no contexto da formação e da prática docente, possibilitaram o compartilhamento de saberes, experiências e aprendizagens da formação e da prática docente. O Pibid constitui-se como uma alternativa de estabelecimento dessa parceria, aproximando a universidade da educação básica, por meio de um trabalho colaborativo.
Three-dimensional Printing-Driving Liver Therapies
Authors: Li Xiaohong , Wen Liang , Liu Jiao , Wang Xiaohong
Published: April 2021

End-stage liver diseases have long been a threat to human health, and so far,
the treatment of these diseases lacks effective means. Allogenic organ transplantation has
become the last straw for most of the patients with end-stage liver diseases. However, this
technique has been greatly limited by the serious shortage of donors and other factors,
such as immune rejection, drug syndrome, and high cost. Recently, the emergence of
three-dimensional (3D) bioprinting technologies, together with the magnetic resonance
imaging (MRI) and computed tomography (CT) techniques, has driven the rapid growth
of this field toward liver therapies. There are several basic requirements for liver 3D bioprinting.
From information collection of diseased livers, to 3D printing of liver substitutes
(containing the major structural, material and functional characters), and to clinical
applications, suitable ‘bioinks’ and ‘bioprinters’ have played essential roles. In this review,
we highlight the advanced ‘bioinks’ and ‘bioprinters’ that have been used for vascularized
and innervated liver tissue 3D bioprinting. Further studies for the incorporation of
biliary networks in the bioartificial livers have been emphasized. It is expected that when
all the bottle-neck problems for liver 3D bioprinting are solved, batch (i.e. mass) and personalized
production of bioartificial livers will make it very easy to treat end-stage liver
diseases.
Regulation of Protein Synthesis: An Approach to Treat Autism Spectrum Disorder (ASD)
Authors: Teixeira Jéssika Poliana , Ramalho Teodorico Castro
Published: April 2021

Autism Spectrum Disorder (ASD) is a disorder with different etiologies and poor
elucidation, characterized by changes in social and cognitive skills. ASD impacts a large
number of people in the world. Surprisingly, in spite of its great importance, just modest progress
has been achieved towards comprehending this pathology and designing new therapies.
The molecular dysfunctions observed in people with autism are evidenced by the interference
in the synthesis of synaptic proteins, which impairs their development and plasticity, leading
to characteristics of individuals with ASD. The present work investigates the mTOR pathway
and the proteins related to its regulation and neurological functioning. The path of protein
synthesis and translation is promising to treat various disorders and its elucidation may, for
example, result in drugs that facilitate the diagnosis and broaden the range of treatments, improving
the quality of life of ASD patients.
Association of Homocysteine Level with Adverse Outcomes in Patients with Acute Ischemic Stroke: A Meta-Analysis
Authors: Zhang Heng , Huang Jiabin , Zhou Yongjing , Fan Yu
Published: April 2021

Background:

Studies on the prognostic value of homocysteine level have
yielded controversial results in patients with acute ischemic stroke (AIS). The aim of this
meta-analysis was to evaluate the prognostic utility of homocysteine among patients with
AIS in terms of recurrent stroke, poor functional outcome or all-cause mortality.

Methods:

Two independent authors searched the articles published in PubMed and Embase
databases prior to March 31, 2020. Original studies that investigated the value of homocysteine
level in predicting recurrent stroke, poor functional outcome (modified
Rankin Scale ≥ 3) or all-cause mortality in AIS patients were eligible.

Results:

Eleven articles (10 studies) that enrolled 19,435 patients with AIS were included.
Meta-analysis indicated that the patients with the highest homocysteine level had an
increased risk of all-cause mortality (risk ratio [RR] 1.40; 95% confidence interval [CI]
1.26-1.55). However, elevated homocysteine level was not significantly associated with
recurrent stroke (RR 1.28; 95% CI 0.99-1.65) or poor functional outcome (RR 1.71; 95%
CI 0.77-3.83).

Conclusion:

Elevated homocysteine level is independently associated with a higher risk
of all-cause mortality but not recurrent stroke or poor functional outcome in patients with
AIS. However, additional well-designed studies are required to confirm the findings of
this meta-analysis.
The Role of Cholesterol Homeostasis in Diabetic Kidney Disease
Authors: Chen Xinyun , Yin Qinghua , Ma Liang , Fu Ping
Published: April 2021

Considerable evidence has proved that disturbed cholesterol metabolism
played a crucial role in diabetic kidney disease. Besides, massive cholesterol depositions
were found in intrinsic renal cells of diabetic kidney disease patients and animal models,
causing cytotoxicity and affecting renal function. Statins could alleviate cholesterol depositions,
podocyte injury, and microalbuminuria of diabetic kidney disease. In this review,
we summarized the process of disturbed cholesterol metabolism and discussed how it induced
kidney dysfunction in diabetic kidney disease.
Advances in Polyaniline for Biomedical Applications
Authors: Pina Cristina Della , Falletta Ermelinda
Published: April 2021

:

Conducting polymers are an outstanding class of materials characterized by
electroconductive properties that make them good candidates for applications in several
sectors. Among them, polyaniline (PANI) is unique for its extraordinary ability to
conduct electricity, biocompatibility, and low toxicity. In spite of its surprising features,
to date, PANI has not found application in practical uses due to its low solubility and processability.
In order to overcome these limitations, different approaches have been developed,
such as polymer grafting processes, PANI-based composites, and blends preparation.
The present review describes the most recent advances on PANI applications in
biomedical fields, such as antioxidant, antimicrobial and antivirus activity, drug delivery,
cancer therapy, etc. In this article, synthetic procedures are also reported which are crucial
for the realization of more innovative materials in the future.
Prospects of Non-Coding Elements in Genomic DNA Based Gene Therapy
Authors: Simna S.P. , Han Zongchao
Published: April 2021

:

Gene therapy has made significant development since the commencement of the first
clinical trials a few decades ago and has remained a dynamic area of research regardless of obstacles
such as immune response and insertional mutagenesis. Progression in various technologies
like next-generation sequencing (NGS) and nanotechnology has established the importance of non--
coding segments of a genome, thereby taking gene therapy to the next level. In this review, we
have summarized the importance of non-coding elements, highlighting the advantages of using full-
length genomic DNA loci (gDNA) compared to complementary DNA (cDNA) or minigene, currently
used in gene therapy. The focus of this review is to provide an overview of the advances and
the future of potential use of gDNA loci in gene therapy, expanding the therapeutic repertoire in
molecular medicine.
Factors Influencing Patient Satisfaction with Healthcare Services Offered in Selected Public Hospitals in Bulawayo, Zimbabwe
Authors: Nyakutombwa Content P. , Nunu Wilfred N. , Mudonhi Nicholas , Sibanda Nomathemba
Published: April 2021

Introduction:

Patient satisfaction with health care services is vital in establishing gaps to be improved, notably in public health facilities utilised by the majority in Low and Middle-Income Countries. This study assessed factors that influenced patient satisfaction with United Bulawayo Hospitals and Mpilo Hospital services in Bulawayo in Zimbabwe.

Methods:

A cross-sectional survey was conducted on 99 randomly selected respondents in two tertiary hospitals in Bulawayo. Chi-squared tests were employed to determine associations between different demographic characteristics and patient satisfaction with various services they received. Multiple Stepwise Linear regression was conducted to assess the strength of the association between different variables.

Results:

Most of the participants who took part in the study were males in both selected hospitals. It was generally observed that patients were satisfied with these facilities' services, symbolised by over 50% satisfaction. However, patients at Mpilo were overall more satisfied than those at United Bulawayo Hospitals. Variables “received speciality services,” “average waiting times,” and “drugs being issued on time” were significant contributors to different levels of satisfaction observed between Mpilo and United Bulawayo Hospitals.

Conclusion:

Generally, patients are satisfied with the services and interactions with the health service providers at United Bulawayo Hospitals and Mpilo Hospitals. However, patients at Mpilo were more satisfied than those at United Bulawayo Hospitals. There is generally a need to improve pharmaceutical services, outpatient services, and interaction with health service provider services to attain the highest levels of patient satisfaction.
New Green Animal Waste Hydrolysis Initiated by Malic Acid
Authors: Hanika Jiri , Rouskova Milena , Sabata Stanislav , Kastanek Frantisek , Solcova Olga
Published: April 2021

Background:

A giant amount of poultry waste represents one of the threats to the environment,
or conversely, a significant source of peptides and other substances in demand. Rational
use of huge quantities of poultry waste, especially after industrial chicken processing, is one of the
pillars of biorefinery of animal wastes.

Introduction:

Six different animal wastes: chicken feathers, cartilages and the residue after meat
separation, sheep wool, rabbit hair, and the rest of the goose feathers from blankets after cleaning
were chosen for a hydrolysis test with malic acid as the initiator.

Result:

The newly designed hydrolysis of animal wastes at 140 oC with malic acid for initiation was
successfully verified for all animal wastes. The resulting hydrolysates contained a mixture of amino
acids, peptides, proteins, glycoproteins, and no salts.

Conclusion:

Hydrolysate applications for agriculture was successfully tested as a biostimulant in
the form of a 10% water solution.
Electrochemical Oxidation of Perfluorooctanoic Acid (PFOA) from Aqueous Solution using Non-Active Ti/SnO2-Sb2O5/PbO2 Anodes
Authors: Singh S.
Published: April 2021

In this study, electrochemical oxidation of perfluorooctanoic acid (PFOA, C7H15CO2H) from aqueous solution was examined in terms of PFOA and total organic carbon (TOC) removal by using Ti/SnO2-Sb2O5/PbO2non-active electrodes. The effects of operating parameters: initial pH (pHo), current density (j), and electrolyte concentration (m) at different time intervals were examined. Specific energy consumption (SEC) was used to determine the process proficiency. The C-C bond between C7F15 was first cleaved and thendegraded into fluoride ions (F−) and short carbon-chain per-fluorinated carboxylic acids (PFCAs) ((∼C2−C7) such as perfluoroethanoic acid (PFEA: C2F5CO2H), perfluoropropanoic acid (PFPA: C3F7CO2H), perfluorobutanoic acid (PFBA: C4F9CO2H), perfluoropentanoic acid (PFPeA: C5F11CO2H), perfluorohexanoic acid (PFHxA: C6F13CO2H), perfluoheptanoic acid (PFHpA: C7F14CO2H). These intermediates by-products were determined using the gas chromatograph-mass spectrometry (GC/MS) analysis. The rate of PFOA decomposition was followed the pseudo-first-order kinetics. About 82%TOC and 94% PFOA removals were formed at the optimal condition of pHo = 3.58, j=168.34 Am-2, and m = 250 mgL-1 at 120 min of electrolysis with SEC = 593 kWh/kg TOC. A plausible degradation mechanism was also proposed at the optimal treatment condition.