bluuebunny/crossref_metadata_2025 huggingface dataset:
De personas y de territorios. La defensa del reino de Murcia entre los siglos XV y la primera mitad del siglo XVIII
Authors: Muñoz Rodríguez Julio D. , Ruiz Ibáñez José Javier
Published: November 2021

Espacio poco poblado y marginal en la Edad Media, el reino de Murcia alcanzó un mayor protagonismo gracias a la relativa pacificación general que trajo la política de los Reyes Católicos. Teniendo que defender un amplio espacio costero de las agresiones corsarias, los territorios que lo integraban se definieron por las demandas que se les hacían para contribuir a la defensa. Así pues, el tipo de amenazas, su origen, su frecuencia y la respuesta que se les dieron fueron decisivos para hacer evolucionar el significado mismo del reino y sus formas de integración en la Monarquía. Esto fue tanto por lo que respecta al innegable crecimiento del poder ejercido en nombre del servicio directo al rey, como por la pervivencia de las capacidades de defensa de las instituciones locales.
Relationships among Family Support, Medical Staff Support, Sick Role Behavior and Physiological Indicators in Hemodialysis Patients
Authors: Chae Young Ran , Kang Hyo Young , Lee Sun Hee , Jo Young Mi , Koo Hyun Ju
Published: November 2021

Background: Family support and medical staff support of hemodialysis patients are related to sick-role behavior, and sick-role behavior is related to physiological indicators such as interdialytic weight gain and control of potassium and phosphorus in the blood.Methods: The subjects were 139 hemodialysis patients. Data were collected on demographic and disease- related characteristics, social support (family support and medical staff support), sick-role behavior, and physiological indicators (interdialytic weight gain, blood potassium, and blood phosphorus).Results: Degrees of family support and medical staff support were both nearly 3.85 points, and sick-role behavior was 3.96 points. Family support (r=0.449, P<0.001) and medical staff support (r=0.421, P<0.001) were positively correlated with sick-role behavior, and sick-role behavior was inversely correlated with interdialytic weight gain (r=-0.218, P=0.010) and blood phosphorus (r=-0.170, P=0.045).Conclusions: The higher the degree of family support and medical staff support, the higher the degree of sick-role behavior. In addition, the higher the level of sick-role behavior, the lower the physiological indicators of interdialytic weight gain and blood phosphorus. Therefore, in order to improve sick-role behavior and physiological indicators, it is necessary to develop and apply an enhanced intervention program through family support and medical staff support.
Animal and Plant Protein Intake and Socioeconomic Status in Young and Middle-Aged Korean Adults
Authors: Park Hyun Ah
Published: November 2021

Background: Dietary intake is affected by socioeconomic status (SES). The aim of this study is to assess adequacy of protein intake, and to investigate the association between SES, in terms of household income and educational attainment, and protein intake according to the protein source i.e., plant or animal protein, in a nationally representative sample of young and middle-aged Korean adults.Methods: We used cross-sectional data from 1,404 Koreans, aged between 19 and 64, who had participated in the 2016-2018 Korea National Health and Nutrition Examination Survey. One day (24-hour) recall data was used to estimate the daily total of animal and plant protein intake. Household income quartiles and educational attainment were assessed by trained interviewers.Results: The proportion of protein intake adequacy, based on the Korean recommended nutrient intake (RNI; 0.91 g/kg/day), was 66.5% (0.8) for males and 58.2% (0.8) for females. After adjustment, household income quartiles were positively associated with animal protein intake with a marginal significance both in males (P=0.051) and females (P=0.080) and showed a marginal negative association with plant protein intake in males (P=0.050) and a marginal positive association in females (P=0.074). Educational attainment was positively associated with total protein (P=0.001), animal protein (P=0.003), and plant protein intake (P=0.002), only in females.Conclusions: One out of three young and middle-aged Korean adults showed protein intake inadequacy. Socioeconomic status, measured by household income and educational attainment, was associated with protein intake in young and middle-aged Korean adults and the associations were more marked in females.
Association between Dietary Carbohydrate Intake and Cardiovascular Risk Factors According to Low-Density Lipoprotein Cholesterol Levels in Korean Adults
Authors: Song SuJin , Lee Yun Jung , Song YoonJu
Published: November 2021

Background: Low-density lipoprotein (LDL) cholesterol is a strong predictor of cardiovascular disease, resulting in the promotion of low-fat diets that emphasize the need to lower LDL cholesterol levels. We investigated the relationship between dietary carbohydrate intake and cardiovascular risk factors according to LDL cholesterol levels in Korean adults who typically consumed high-carbohydrate, low-fat diets.Methods: A total of 25,925 Korean adults were selected from the 2007-2015 Korea National Health and Nutrition Examination Surveys. Dietary carbohydrate intake was grouped into quintiles and cardiovascular risk factors included obesity, metabolic syndrome, type 2 diabetes, and dyslipidemia. Multiple logistic regression models were used to examine association between carbohydrate intake and cardiovascular risk factors by sex and LDL cholesterol levels.Results: Subjects with LDL cholesterol ≥130 mg/dL had significantly less energy and fat intake than those with LDL cholesterol <130 mg/dL both in men and women. In men, a higher carbohydrate intake was related to increased prevalence of atherogenic dyslipidemia and low high-density lipoprotein (HDL) cholesterol regardless of LDL cholesterol levels. Meanwhile, dietary carbohydrate intake was positively associated with low HDL cholesterol but inversely associated with hypercholesterolemia only in women with LDL cholesterol <130 mg/dL.Conclusions: High carbohydrate intake in Korean adults is associated with low HDL cholesterol or atherogenic dyslipidemia regardless of LDL cholesterol levels. Carbohydrate intake should be carefully recommended according to the lipid profiles of individuals for the prevention and management of cardiovascular disease.
Factors of Specific Comorbidities Severity on the Risk of Mortality among Breast Cancer Survivors
Authors: Seo Hwa Jeong
Published: November 2021

Background: For cancer patients, comorbidities affect the risk, progression, and process of treatment. They negatively affect prognoses by increasing mortality. It is therefore necessary to predict prognoses accurately for cancer survivors by measuring comorbidities and their severity.Methods: In this study, the frequency of comorbidities was analyzed on the basis of the Charlson comorbidity index (CCI) in breast cancer patients drawn from the National Health Insurance Service-National Sample Cohort data. This study examined the relative effects of certain factors (age, diagnosis period, and CCI) between deaths and cancer survivors with logistic regression analysis. We applied Cox's proportional hazard regression analysis to predict the risk of mortality according to CCI as a survival predictor of breast cancer patients using three models with correction for age, including the body mass index (BMI), smoking status, alcohol intake, and childbirth history.Results: The frequency analysis based on CCI found that the most frequent type of condition was pulmonary disease (2,262; 21.5%), followed by peptic ulcer (2,019; 19.2%), and metastatic cancer (1,821; 17.3%). The older one gets, the greater one’s risk of mortality with more severe comorbidities. Age and BMI led to greater risk of mortality, with correction for the variables (age, BMI, smoking status, alcohol intake and childbirth history) that could cause confounding.Conclusions: Severity of comorbidities significantly increased the risk of mortality for breast cancer patients. In particular, those cancer survivors who are aged ≥60 years, who have high BMI, and who once smoked need to get continuous care due to poor prognoses.
Modeling the effects of insecticides and external efforts on crop production
Authors: Misra A.K. , Patel Rahul , Jha Navnit
Published: November 2021

In this paper a nonlinear mathematical model is proposed and analyzed to understand the effects of insects, insecticides and external efforts on the agricultural crop productions. In the modeling process, we have assumed that crops grow logistically and decrease due to insects, which are wholly dependent on crops. Insecticides and external efforts are applied to control the insect population and enhance the crop production, respectively. The external efforts affect the intrinsic growth rate and carrying capacity of crop production. The feasibility of equilibria and their stability properties are discussed. We have identified the key parameters for the formulation of effective control strategies necessary to combat the insect population and increase the crop production using the approach of global sensitivity analysis. Numerical simulation is performed, which supports the analytical findings. It is shown that periodic oscillations arise through Hopf bifurcation as spraying rate of insecticides decreases. Our findings suggest that to gain the desired crop production, the rate of spraying and the quality of insecticides with proper use of external efforts are much important.
Модифікації 7-гідрокси-3-(бензотіазол-2-іл)кумарину
Authors: Шокол Т.В. , Супрун А.В. , Глібов Є.К. , Москвіна В.С. , Хиля В.П.
Published: November 2021

Проведено модифікацію 7-гідрокси-3-(бензотіазол-2-іл)кумарину, що містить диметиламінометильну та формільну групи в 8-му положенні бензопіран-2-онового циклу, корисні для подальших структурних перетворень. Амінометилюванням 7-гідрокси-3-(бензотіазол-2-іл)кумарину за класичних умов реакції Манніха з використанням надлишку формаліну отримані похідні системи дигідрооксазинокумарину. На основі 8-діалкіламінометил-7-гідрокси-3-(бензотіазол-2-іл)кумарину переамінуванням з бензиламінами синтезовані відповідні основи Манніха, в результаті взаємодії з енамінокетонами о-гідроксіаренів — похідні гомо - і зофлавону, за умов реакції Даффа — 3-(бензотіазол-2-іл)-7-гідрокси-8-формілкумарин. Останній у реакції з 4-нітрофенацилбромідом утворює похідну системи фуро[2,3-h]кумарину. Досліджено рециклізації 3-(бензотіазол-2-іл)-7-гідрокси-8-(4-оксо-4Н-3-хроменілметил)-2Н-2-хроменону під дією бінуклеофілів.
Фосфорилювання вірусних білків — важлива умова репродукції рослинних вірусів
Authors: Максименко Л.О. , Пархоменко Н.Й.
Published: November 2021

Фосфорилювання білків характерно для структурних білків у вірусу мозаїки цвітної капусти, А-вірусу картоплі (АВК), вірусу шарки сливи та ін. Цей процес необхідний для розвитку вірусної інфекції в рос лині. Х-вірус картоплі (ХВК) — типовий представник роду Potexvirus. Встановлено, що капсидний білок ХВК здатний фосфорилюватися в стандартному інкубаційному середовищі in vitro, яке містило (гамма-32Р)АТФ. На відміну від цього білок ХВК у стандартному інкубаційному середовищі за наявності (альфа-32Р)АТФ не фосфорилюється. Таким чином, кінцевий фосфат АТФ відіграє головну роль у фосфорилюванні білка ХВК. Фосфорильований білок ХВК у системі in vivo був виявлений шляхом експонування нітроцелюлозного фільтра з імуноблотом на рентгенівській плівці РМ-1. У результаті був одержаний автограф фосфорильованого in vivo структурного білка ХВК. Концентрація іонів Са2+ та ЕДТА у системі фосфорилювання in vitro впливає на процес фосфорилювання структурного білка ХВК. За наявності в системі фосфорилювання in vitro 10 мМ ЕДТА та 10 мМ СаCl2 процес фосфорилювання структурного білка ХВК пригнічується. Явище фосфорилювання структурного білка ХВК використовується в процесах репродукції вірусу в інфікованій клітині
Effects of COVID-19, diabetes mellitus, and cardiovascular diseases on insulin receptor substrate-1 amount in the blood plasma of patients
Authors: Tronko M. D. , Pushkarev V. V. , Sokolova L. K. , Cherviakova S. A. , Belchina Yu. B. , Kovzun O. I. , Pushkarev V. M.
Published: November 2021

Insulin receptor substrate (IRS) is a key adapter protein mediating effects of insulin and insulin-like growth factors (IGF) in cells. IRS-1 is a member of the insulin receptor substrate family, which is associated with tumor initiation and progression. The aim of the study is to determine the level of IRS-1 in the blood of patients (n = 81) with diabetes mellitus and COVID-19. IRS-1 was determined with enzyme-linked immunosorbent assay (ELISA) (Elabscience, USA). The measurements were performed at an optical wavelength of 450 nm. The level of IRS-1 in the blood plasma of patients with COVID-19 was much (from 3.5 to more than 6 times) higher than that in the blood of healthy people. The IRS-1 amounts in COVID-19 patients with diabetes and diabetes + CVD were significantly higher than in patients with COVID-19 without concomitant diseases. The level of IRS-1 in blood plasma may be one of the promising markers of COVID-19.
Вплив форми частинок на теплофізичні властивості модельних рідинних систем. Розчини твердих сфероциліндрів
Authors: Grigoriev A.N. , Kuzovkov Yu.G. , Markov I.V. , Bulavin L.A.
Published: November 2021

Методом Монте-Карло в iзотермiчно-iзобаричному ансамблi визначено теплофiзичнi характеристики систем твердих сфероцилiндрiв рiзного ступеня видовженостi: густину, адiабатичний та iзотермiчний модулi пружностi, коефiцiєнт теплового роз-ширення та коефiцiєнт Джоуля–Томсона за приведеної температури T = 1,0 та при-ведених тискiв P = 1,0 i 3,5. Показано, що вплив форми частинок за умови сталостi їх об’єму на теплофiзичнi властивостi дослiджених розчинiв здiйснюється опосередковано не через коефiцiєнт пакування частинок, а через вiльний або доступний об’єм.
Поляризовність двошарового метал-оксидного нано-дроту
Authors: Korotun A.V. , Karandas Ya.V. , Reva V.I. , Titov I.M.
Published: November 2021

В роботi одержано спiввiдношення для частотних залежностей дiйсної й уявної частин та модуля компонентiв тензора поляризовностi, а також перерiзiв поглинання i розсiювання метал-оксидних нанодротiв. Дослiджено граничнi випадки “товстого” I “тонкого” зовнiшнього шару оксиду. Чисельнi розрахунки проведено для дротiв Al, Cu i Ag, вкритих шаром власного оксиду. Розглянуто випадки, коли дiелектрична проникнiсть оксиду є постiйною величиною або є функцiєю частоти. В останньому випадку для визначення цiєї залежностi було використано апроксимацiю експериментальних кривих частотних залежностей показникiв заломлення та екстинкцiї. Проаналiзовано вплив змiни товщини оксидного шару на поведiнку частотних залежностей поляризовностi i перерiзiв поглинання i розсiювання. Встановлено, що наявнiсть оксиду приводить до зменшення частоти поверхневих плазмонiв у двошарових нанодротах внаслiдок впливу класичних розмiрних ефектiв.
Association Between English Proficiency and Timing of Analgesia Administration After Surgery
Authors: Plancarte Carlos A. , Hametz Patricia , Southern William N.
Published: November 2021

BACKGROUND

Pediatric patients from families with limited English proficiency (LEP) are at risk for health care disparities. We examined timeliness of analgesic administration in pediatric postoperative patients with a limb fracture from LEP versus non-LEP families.

METHODS

This was a retrospective cohort study of children aged 1 year to <18 years of age, hospitalized to the general inpatient floor after surgical correction of single limb fractures between July 2016 and July 2019 were eligible. Patients whose consent was in a non-English language or for whom an interpreter was used were classified as from LEP families. The primary outcome was time to first analgesia. Secondary outcomes included time to first opioid, proportion with any analgesia and opioid analgesia, and number of pain assessments. Associations between LEP and outcomes were tested by using χ2 tests, Kaplan–Meier plots, and Cox proportional hazards models.

RESULTS

We examined 306 patients, of whom 59 (19%) were from LEP families. Children in LEP families were significantly less likely to receive any analgesia (86.4% vs 96.8%, P ≤ .01) and experienced longer time to first analgesia in unadjusted (hazard ratio = 0.68, 95% confidence interval: 0.50–0.92) and adjusted analyses (hazard ratio = 0.68, 95% confidence interval: 0.50–0.94). There was no significant association between LEP and time to first opioid, proportion given opioid analgesia, or number of pain assessments.

CONCLUSION

Hospitalized children from LEP families experience a longer time to analgesia administration after surgery. The mechanisms that lead to these differences in care must be identified so that interventions can be designed to address them.
Reducing Delays in a Pediatric Procedural Unit With Ultrasound-Guided Intravenous Line Insertion
Authors: Peters Megan E. , Boriosi Juan P. , Sklansky Daniel J. , Hollman Gregory A. , Eickhoff Jens C. , Christenson Devon K. , Shadman Kristin A.
Published: November 2021

OBJECTIVES

Delay in vascular access is a leading cause of procedure delay in our pediatric procedure and infusion center. Use of ultrasound decreases time to peripheral intravenous catheter (PIV) insertion; however, ultrasound availability in our center was limited to an external venous access team (VAT). The objective of this project was to reduce PIV-related delays by 25%.

METHODS

Stakeholders convened and theorized that creating a unit-based nurse team specializing in ultrasound-guided peripheral intravenous catheter (USgPIV) insertion would facilitate faster access and a reduction in delayed procedures. An initial plan-do-study-act cycle was performed, training 2 nurses in USgPIV placement. Subsequent cycles were focused on increasing availability of USgPIV-trained nurses. The outcome measure was the rate of procedures delayed by PIV placement, analyzed on a statistical process control U-chart. The process measure was the percentage of USgPIV placements requiring consultations to the VAT, analyzed on a statistical process control P-chart. The balancing measure was the success rate per method of insertion. Comparisons of success rates were conducted by using a χ2 test and Fisher’s exact test.

RESULTS

The mean rate of procedures delayed because of vascular access fell by special cause variation from 10.8% to 6.4%. The mean VAT consultation rate fell from 86.4% to 32.0%. The VAT had higher rates of overall success (100% vs 87%; P = .01) and first-attempt success (93% vs 77%; P = .03) compared with unit nurse USgPIV placement.

CONCLUSIONS

Unit-based USgPIV placement in a pediatric procedural center was successfully implemented, with a significant decline in procedures delayed by PIV access.
Flushing an Offensive Term for Vancomycin Infusion Reaction From the Electronic Medical Record
Authors: Konold Victoria J.L. , Brothers Adam W. , Kronman Matthew , Pak Daniel , Bettinger Brendan , Weissman Scott J.
Published: November 2021

BACKGROUND

The medical establishment continues to be complicit in the degradation of native peoples of the United States through the use of the racist phrase “red man syndrome” (RMS) to describe the histamine-release syndrome that accompanies vancomycin infusion.

METHODS

Five months after the transition from 1 electronic health record to another at our freestanding children’s hospital, our antimicrobial stewardship team reviewed all active allergy records to identify and then replace use of RMS terminology with preferred alternative “vancomycin flushing syndrome.” In partnership with institutional stakeholders, we also launched an educational campaign and instituted in the electronic health record an autocorrect functionality to prevent new RMS entries.

RESULTS

We identified allergy records for 21 034 individual patients. Vancomycin was an allergen for 445 (2.1%) patients, and RMS-related terminology appeared in 274 (61.6%) of these records; we replaced all RMS instances with the vancomycin flushing syndrome term. During the 3-month period after the intervention, we identified allergy records for 8648 additional patients, with vancomycin as allergen in 65 (0.7%) and with RMS terminology identified and replaced in 29 (44.6%). In addition to the lower rate of RMS among allergy records after the intervention, we detected 3 instances of alternative terminology use.

CONCLUSIONS

Implementing an institutional-level change in terminology, even for racist language, requires education, reinforcement, and continued surveillance. To effectively replace this term, we need the support of national stakeholders to remove this language from our medical education systems, our textbooks, and our clinical lexicon.
The Impact of Obesity on Disease Severity and Outcomes Among Hospitalized Children With COVID-19
Authors: Tripathi Sandeep , Christison Amy L , Levy Emily , McGravery Jeremy , Tekin Aysun , Bolliger Dawn , Kumar Vishakha K. , Bansal Vikas , Chiotos Kathleen , Gist Katja M. , Dapul Heda R. , Bhalala Utpal S. , Gharpure Varsha P , Heneghan Julia A. , Gupta Neha , Bjornstad Erica C. , Montgomery Vicki L , Walkey Allan , Kashyap Rahul , Arteaga Grace M.
Published: November 2021

OBJECTIVE

To describe the impact of obesity on disease severity and outcomes of coronavirus disease 2019 (COVID-19) among hospitalized children.

METHODS

This retrospective cohort study from the Society of Critical Care Medicine Viral Respiratory Illness Universal Study registry included all children hospitalized with COVID-19 from March 2020 to January 2021. Obesity was defined by Centers for Disease Control and Prevention BMI or World Health Organization weight for length criteria. Critical illness definition was adapted from National Institutes of Health criteria of critical COVID. Multivariate mixed logistic and linear regression was performed to calculate the adjusted odds ratio of critical illness and the adjusted impact of obesity on hospital length of stay.

RESULTS

Data from 795 patients (96.4% United States) from 45 sites were analyzed, including 251 (31.5%) with obesity and 544 (68.5%) without. A higher proportion of patients with obesity were adolescents, of Hispanic ethnicity, and had other comorbidities. Those with obesity were also more likely to be diagnosed with multisystem inflammatory syndrome in children (35.7% vs 28.1%, P = .04) and had higher ICU admission rates (57% vs 44%, P < .01) with more critical illness (30.3% vs 18.3%, P < .01). Obesity had more impact on acute COVID-19 severity than on multisystem inflammatory syndrome in children presentation. The adjusted odds ratio for critical illness with obesity was 3.11 (95% confidence interval: 1.8–5.3). Patients with obesity had longer adjusted length of stay (exponentiated parameter estimate 1.3; 95% confidence interval: 1.1–1.5) compared with patients without obesity but did not have increased mortality risk due to COVID-19 (2.4% vs 1.5%, P = .38).

CONCLUSION

In a large, multicenter cohort, a high proportion of hospitalized children from COVID-19 had obesity as comorbidity. Furthermore, obesity had a significant independent association with critical illness.
Multifetal Gestations and Associated Perinatal Risks
Authors: Duffy Cassandra R.
Published: November 2021

Along with the rise of assisted reproductive technology, multifetal gestations increased dramatically. Twin pregnancies account for 97% of multifetal pregnancies and 3% of all births in the United States. Twins and higher-order multiples carry increased risks of obstetric, perinatal, and maternal complications; these risks increase with increasing fetal number. Neonatal morbidity and mortality in multifetal gestations is driven primarily by prematurity. Both spontaneous and indicated preterm births are increased in multifetal gestations, and only a limited number of strategies are available to mitigate this risk. No single intervention has been shown to decrease the rate of spontaneous preterm birth in most twin pregnancies. Low-dose aspirin prophylaxis is recommended in all multifetal pregnancies to reduce the risk of preeclampsia and its associated complications. Antenatal management of multifetal gestations depends on chorionicity, which should be established using ultrasonography in the first trimester. Unlike dichorionic twin gestations, monochorionic pregnancies experience unique complications because of their shared vascular connections, and therefore, need frequent ultrasound surveillance. Even uncomplicated twin gestations have higher rates of unanticipated stillbirth compared with singletons. Delivery of twin pregnancies is generally indicated in the late preterm to early term period depending on chorionicity and other clinical factors. For most diamniotic twin pregnancies with a cephalic presenting fetus, vaginal delivery after 32 weeks’ gestation is a safe and reasonable option with high rates of success and no increased risk of perinatal morbidity.
Cardiovascular Disease in Pregnancy
Authors: Mcilvaine Susan , Feinberg Loryn , Spiel Melissa
Published: November 2021

Cardiovascular disease remains a major contributor to rising maternal morbidity and mortality. Both the pregnant woman and fetus are exposed to many potential complications as a result of the physiologic changes of pregnancy. These changes can exacerbate existing cardiac disease, as well as lead to the development of de novo issues during gestation, delivery, and the postnatal period. For women with preexisting cardiac disease, including congenital malformations, valvular disease, coronary artery disease, and aortopathies, it is crucial that they receive multidisciplinary evaluation, counseling, and optimization before conception, as well as close monitoring and medication management during pregnancy. Close monitoring is also essential for patients who develop cardiovascular complications such as preeclampsia, cardiomyopathy, congestive heart failure, coronary events, and arrhythmias during pregnancy. In addition, concerning disparities in maternal morbidity and mortality exist across many dimensions, in part because of the lack of uniformity of care in different treatment settings. Establishment of multidisciplinary cardio-obstetric teams including representatives from cardiology, anesthesia, obstetrics, maternal-fetal medicine, and specialized nursing has proven instrumental to delivering evidence-based and equitable care to high-risk patients. Multidisciplinary teams should work to guide these patients through the preconception, antepartum, delivery, and postpartum phases to ensure appropriate care for weeks to years after pregnancy.
Kalmykia in the Space of Russian-Mongolian Relations in the 20th – Early 21st Centuries: Historical and Cultural Aspect
Authors:   Federal Research Centre the Southern Scientific Centre of the Russian Academy of Sciences, Ochirova Nina , Sukhebaatar Nadmidyn ,   Mongolian State University of Education
Published: November 2021

Introduction This article within the framework of Russian-Mongolian relations examines the regional aspect of cultural cooperation between Mongolia and Kalmykia in the Soviet and post-Soviet periods. The authors investigated a wide range of problems related to the place and role of Kalmykia in the history of Russian-Mongolian relations, studied the development of multifaceted interaction between two kindred peoples. Methods and materials. From a methodological point of view, this study is an experience of building a comprehensive vision of the problem. An interdisciplinary, comprehensive approach to solving current research problems makes it possible to synthesize all relevant aspects of studying the historical and cultural aspects of regional cooperation between Kalmykia and Mongolia within the framework of Russian-Mongolian relations. Analysis. 2021 marks the 100th anniversary of the establishment of Soviet-Mongolian official diplomatic relations. The Agreement between Mongolia and Russia signed on November 5, 1921 strengthened the military-political cooperation between the two countries, served as a broad international recognition of Mongolia as a sovereign state and played an important stabilizing role in the difficult situation in the Far East. In the 90s of the last century, Russia and Mongolia engaged in profound transformations. The scale of the work carried out by our countries demanded to shift all their attention to solving internal problems, which undoubtedly had a negative impact on the level of relations between the two states. Later, having solved the problems of radical transformations of society, Russia and Mongolia began to restore relations, but on completely new principles. In these conditions, along with other industries, the sphere of cultural interaction between Russia and Mongolia, the development of regional cooperation, becomes significant. One of the Russian regions is Kalmykia, which is linked with Mongolia by ancient historical roots, the unity of culture, religion, language and tradition. These factors play an important role in the further strengthening of good neighborly relations between Russia and Mongolia, in the development of regional cultural cooperation. Results. Studying the history of interaction between the two fraternal peoples in the past and present in the aspect of Russian-Mongolian relations provides rich material for an objective assessment of events in specific historical conditions. Kalmykia, like the border regions of Russia, makes a certain contribution to the strengthening of Russian-Mongolian relations.
Digital Museumification As a Promising Mechanism for the Preservation and Presentation (Representation) of Historical and Cultural Heritage: Towards the Formulation of the Question
Authors:   Volgograd State University, Zolotovskiy Vladimir
Published: November 2021

Introduction. During the 20th century the functions and essence of museums have undergone changes. One of the most relevant functions of modern museums is museumification. The purpose of the paper is to reveal the features of digital museumification as a promising direction and an actual form of museumification of material and non-material objects included in the socio-cultural environment. Discussion. The undertaken historiographical review allowed us to conclude that there is a sufficient methodological and factual basis for a comprehensive study of the essence of museumification. At the same time, many problems of the theory and practice of museumification have not even received a problematic definition. Analysis. Museumification is of particular importance in the activities of saving, preserving, and introducing cultural heritage objects into the modern socio-cultural environment. In modern domestic and foreign practice museumification develops in two main directions: removal from the natural area and museumification of cultural heritage monuments through actualization or introduction into the socio-cultural environment. The monument, which is a harmonious part of the socio-cultural environment, does not require artificial conservation of the habitat or the area of the monument. It is determined that for such objects of museumification it is reasonable to use the concept of “dynamic museumification”. The most adequate form of “dynamic museumification” should be considered digital museumification. Results. Digital museumification should be understood as an activity for the transformation of cultural heritage objects into living objects that develop together with their cultural space and socio-cultural environment. Digital museumification is presented as a combination of actions and means pointed at ensuring the implementation of preservation and popularizations tasks within the framework of the “smart city” system being formed. Digital museumification objectively makes it necessary to create open information bases for all interested persons. The detected connection between the space of a monument and the channels of forming the historical memory determines the need for organizing digital museumification in a digital creative urban space.
QUACKENBOS COMO ANTÍDOTO A ORTIZ & PARDAL: O ENSINO DA GRAMÁTICA DA LÍNGUA PORTUGUESA NO PARECER DE RUY BARBOSA, 1882
Authors: WARDE MIRIAN JORGE , OLIVEIRA FERNANDO RODRIGUES DE
Published: November 2021

RESUMO: O objetivo deste artigo é contribuir para as já avançadas pesquisas, no Brasil, referentes ao método intuitivo. São examinados dois livros citados por Ruy Barbosa em seu Parecer de 1882 sobre o ensino primário no Município da Corte: Illustrated lessons in our lenguage; or how to speak and write correctly. Designed to teach english grammar, without technicalities, de George Payn Quackenbos, recomendado por Barbosa como antídoto a Grammatica analytica e explicativa da língua portugueza, de José Ortiz e Candido Pardal, em circulação nos anos de 1870 e 1880, especialmente nas escolas primárias do Rio de Janeiro. Sobre Grammatica analytica, destaca-se sua organização fundada no conceito de gramática como arte de escrever e falar bem, o que denota sua filiação ao modelo geral e filosófico greco-latino, portanto, seu descompasso em relação à renovação científica que vinha ocorrendo na Linguística no século XIX. Para apresentação contextuada das Illustrated lessons... - e considerando que o seu autor ainda não ganhou estudos no Brasil sobre o ensino de gramática, composição e áreas adjacentes, e sobre o método intuitivo -, o artigo situa esse livro em relação às demais publicações de Quackenbos, bem como o seu enraizamento intelectual no “enlightenment” escocês e sua declarada adesão às lições de coisas (object lessons). Com isso, verifica-se em Ruy Barbosa um grau razoavelmente alto de consistência nas críticas que enceta contra o conservadorismo linguístico presente na Instrução Primária da Corte e sua atualidade em relação aos estudos então mais recentes que dão base a novas propostas pedagógicas, ditas modernas.
Selection strategies in agronomic characters in progenies F3:4 of transgenic soy RR
Authors: Carneiro Anna Regina Tiago , Hamawaki Osvaldo Toshiyuki , Nogueira Ana Paula Oliveira , Silva Arthur Felipe Eustáquio e , Hamawaki Raphael Lemes , Hamawaki Cristiane Divina Lemes
Published: November 2021

ABSTRACT The selection indexes aggregate information to multiple characters and, with this, they are able to carry out the selection of a set of variables simultaneously. The objective was to verify the genetic potential of agronomic traits and to select soybean F3:4 progenies based on different selection strategies. 123 progenies and the parents were sown in randomized blocks with two replications. The gains of direct selection by the indexes, the sum of “ranks” and the genotype-ideotype were lower for all characters when compared to the gains of direct and indirect selection. The rank sum index stood out for achieving the highest total gain with 37.11%. The index of the genotype-ideotype obtained a lower gain (-0.48%) for the character number of days for flowering compared to the sum index of “ranks” (-0.54%) and reached a negative gain for the attribute insertion height of the first pod with -1.82%. The genetic potential of the F3:4 population is high and allows different selection strategies to be applied to reach superior genotypes. The progenies UFU 72, UFU 116, UFU 86, UFU 45, UFU 117, UFU 56, UFU 5, UFU 106, UFU 6, UFU 4, UFU 73, UFU 101, UFU 96, UFU 90, UFU 123, UFU 116, UFU 88, UFU 65, UFU 70, UFU 3, UFU 69 and UFU 37 were selected by both selection indexes. The UFU 72, UFU 90, UFU 88 and UFU 69 progenies are agronomically superior both in direct and indirect selection, as in Mulamba and Mock (1978) sum of “ranks” selections and genotype-ideotype.
NARRATIVAS DO CUIDADO A CRIANÇAS EM UM NASF: A ESTRATÉGIA RODINHA DE CONVERSA
Authors: Alaion Allana Rodrigues , Machado Adriana Marcondes
Published: November 2021

Resumo Em um território permeado por situações de vulnerabilidade social, as demandas de saúde mental dos adultos carregam desafios em relação às infâncias vividas nas famílias, convocando um Núcleo de Apoio à Saúde da Família (NASF) em um município da Baixada Santista a se debruçar sobre isto. Esse trabalho refere-se a uma pesquisa-intervenção realizada a partir da atuação de uma psicóloga nesse NASF para acolher as demandas de saúde mental infantil, sendo desenvolvida uma estratégia denominada Rodinha de Conversa. Como recurso metodológico foram utilizados diários de campo e construídas narrativas como forma de dar visibilidade a histórias vividas, ao território e à estratégia de trabalho desenvolvida. As Rodinhas de Conversa serviram como analisadoras do funcionamento da rede de serviços e dos fluxos nos trabalhos da atenção básica, e romperam uma lógica diagnóstica de triagem.
Different approaches for aesthetic rehabilitation of discolored nonvital anterior teeth
Authors: DIAS Pâmella Coelho , FRANCO Fernanda Blanco Machado Junqueira , PALMA-DIBB Regina Guenka , SILVA Rafael Cândido Pedroso e , FARAONI Juliana Jendiroba
Published: November 2021

ABSTRACT An ideal aesthetic standard consists of facial and smile harmony. Discolored teeth generally cause an imbalance in facial aesthetics, leading to low self-esteem and disturbance in social relationships. Causes of teeth discoloration are classified as intrinsic or extrinsic. Bleaching is considered a safe and effective treatment for discolored nonvital teeth and can be associated with restorative treatment to properly correct the dental color and maximize the aesthetic results. This paper aims to present two case reports of single discolored nonvital anterior teeth and the protocol used to reestablish the dental harmony of these patients by bleaching and direct composite resin restoration. To exert minimally invasive dentistry is very important to preserve tooth structure and reduce the risk of fracture. Internal bleaching, although may not be sufficient to reestablish the aesthetic in some cases, it is important to minimize dental preparation to perform an indirect or direct restoration. Dentists must take into account the patients expectations, dominate the restorative technique and know the dental materials to properly be able to restore function and aesthetics and consequently improve life quality and social relationships.
Dental caries in children with Down syndrome and associated factors
Authors: HASHIZUME Lina Naomi , MOREIRA Mauricio José Santos , HILGERT Juliana Balbinot
Published: November 2021

ABSTRACT Objective: The aim of this study was to assess dental caries and associated factors in children with Down syndrome (DS). Methods: The sample consisted of children between 6 and 12 years old being 67 with DS and 46 without DS. Caries experience and gingival bleeding index were recorded. Questionnaire with socio-demographic questions was applied to children’s caregivers. Crude and adjusted prevalence ratios for caries in primary and permanent teeth were calculated by means of Poisson regression with robust variance. Results: Children with DS and without DS showed similar results for caries experience. Only age was associated with caries at permanent teeth. None of the variables were associated with caries at primary teeth in both groups of children. Conclusion: It can be concluded that social factors and access to dental services analyzed in this study were not associated with dental caries in children with DS syndrome. Furthermore, caries experience for children with DS and those without the syndrome were not different based on this study.
Importance of syngap1 syndrome diagnosis in autism spectrum disorder for dental treatment
Authors: ZINK Adriana Gledys , PINHO Marcelo Diniz de , PINHO Marcel Zink de , MARTINS Fernando Baeder de
Published: November 2021

ABSTRACT This paper reports on a patient with initial clinical diagnosis of Autism Spectrum Disorder level 3 and genetically confirmed as Syngap1 Syndrome (Synaptic RasGTPase activating protein). This study aimed to show the importance of genetic testing and accurate diagnoses associated with syndromes for the planning and accomplishment of dental treatments. The new diagnosis allowed reorganization of the plan and was useful in decision-making for the clinical practice of dental treatment for patients diagnosed with Syngap1.
Evaluation of sclerotherapy with different dilutions of ethanolamine oleate in the treatment of oral varicose veins
Authors: MORAES Bianca Montes , ARÊDES Mariana Marinho , VILAÇA Cristiano Magalhães Moura , BARKI Maria Carolina de Lima Jacy Monteiro , WERNECK Juliana Tristão , FONTES Karla Bianca Fernandes da Costa , PICCIANI Bruna Lavinas Sayed
Published: November 2021

ABSTRACT Objective: This study aim to evaluate the effectiveness of sclerotherapy protocols with different dilutions of ethanolamine oleate in the treatment of oral varicose veins. Methods: Clinical data and images of 14 cases treated with sclerotherapy were analyzed and descriptive analyses were performed. Results: Females (58%) and white skin color (83%) prevailed. Age varied between 14 and 79 years, with 47 years on mean (SD = 19 years). The most common anatomical locations were the buccal mucosa and lower lip. The final volume of the sclerosing agent (Ethamolin®) ranged from 0.4 to 4.3ml and the concentration ranged from 5% to 100%. The number of sessions ranged from 1 to 12 and the number of points per application was 1 to 7 points. Pain and edema were seen in 43% and 29% of patients, respectively. Conclusion: Sclerotherapy with monoethanolamine oleate diluted in anesthetic is a safe and effective option for the treatment of this lesion, regardless of concentration. However, edema and pain seem to be directly associated with increased drug concentration.
Ellis-Van Creveld Syndrome, neonatal teeth and breastfeeding impairment: a case report
Authors: DELGADO Renata Zoraida Rizental , COUTO Ana Carolina Fernandes , MARCATO Romulo Andrade , PORTINHO Danielle , FROSSARD Wanda Terezinha Garbelini , GARBELINI Cássia Cilene Dezan
Published: November 2021

ABSTRACT Because of multisystemic impairment in patients with Ellis-van Creveld syndrome, multidisciplinary care may be demanded since birth to assure breastfeeding. This report presents a case of an Ellis-van Creveld infant that was facing breastfeeding difficulties because of maxillary neonatal teeth. A 3 months old male infant with Ellis-van Creveld syndrome was referred to Pediatric Dentistry Department because of two upper neonatal teeth causing breastfeeding difficulties. Clinical examination revealed that teeth position was compatible to 51 and 61, and both presented uncommon ectopic soft tissue placement, conical crown and hypoplastic enamel covered by a large amount of dental biofilm. Radiography indicated they were of normal series and had 2/3 of crown completion. Due to teeth mobility that impaired breastfeeding, treatment option was exodontia. Early tooth eruption, such as in natal and neonatal teeth, by itself can’t be considered a reason for exodontia. But exodontia must be considered when an early erupted tooth(s) impairs breastfeeding, especially in systemically compromised infants. In this present case report, after teeth extraction, the infant was able to breastfeed and gain weight properly.
Characterization of Behavioral Symptoms of Older Adults with Neurocognitive Disorder by the Report of Informal Caregivers
Authors: Souza Yara Luana Pereira , Schmidt Andreia
Published: November 2021

Abstract: Behavioral symptoms of people with dementia can negatively affect the mental health of informal caregivers. The aims of this study were to describe the behavioral symptoms of adults diagnosed with dementia based on the report of their caregivers and to characterize the caregivers regarding the level of hope, burden and stress related to care. Twenty informal caregivers participated in the study, with an average age of 54 years, predominantly daughters and wives of the patients, who granted an interview and responded to instruments regarding burden and stress, hope, patient’s characteristics and behavioral problems. Despite a high level of hope, the participants had a burden level compatible with that of caregivers of chronic patients. The most mentioned challenging behaviors were difficulties in carrying out activities of daily living and aggressiveness, predominantly characterized as behavioral excesses. We emphasize the importance of interventions with caregivers of people with neurocognitive disorder, oriented to the management of challenging behaviors.
Cuidados de transição: análise do conceito na gestão da alta hospitalar
Authors: Bernardino Elizabeth , Sousa Solange Meira de , Nascimento Jaqueline Dias do , Lacerda Maria Ribeiro , Torres Danelia Gomez , Gonçalves Luciana Schleder
Published: November 2021

RESUMO Objetivo analisar o conceito Cuidados de Transição no contexto da gestão da alta hospitalar. Método reflexão analítica utilizando-se a análise conceitual de Walker e Avant: seleção do conceito; definição do objetivo, identificação do uso do conceito (busca na literatura e dicionários entre setembro-dezembro/2019 nas bases de dados: PubMed, Biblioteca Virtual em Saúde e SCOPUS. Consideraram-se 77 artigos que contemplaram conceito e outros termos que corroboraram o estudo; para fins metodológicos, 12 estudos possibilitaram a análise); definição dos atributos; descrição de caso modelo; descrição de casos adicionais; definição de antecedentes e consequentes; definição de indicadores empíricos. Resultados os antecedentes cuidados fragmentados e reinternação são comuns ao conceito. Identificaram-se atributos cuidado integrado, colaboração profissional, coordenação, planejamento da alta, comunicação, integração profissional e gerenciamento de casos. Conclusão e implicações para a prática foi oportuno analisar o conceito em conjunto com termos relacionados ao contexto da alta hospitalar. Cuidados de Transição são práticas coordenadas e eficazes para a Continuidade dos Cuidados na transferência do usuário na alta hospitalar; nesse contexto, as Enfermeiras de Ligação são potenciais protagonistas para estar à frente nesse processo de Integração. As especificidades do conceito poderão favorecer a sua compreensão e a construção de conhecimentos que repercutam no cuidado coordenado e contínuo.
Ultrasonic wave propagation in thermally treated concrete up to 400 ºC
Authors: Viana Ana Carolina Costa , Moraes Poliana Dias de , Padaratz Ivo José
Published: November 2021

Abstract The ultrasonic pulse velocity, obtained by ultrasonic non-destructive testing, has been applied to evaluate the concrete integrity. The attenuation parameters have shown more sensitivity to damage detection in the microstructure of concrete since they consider the entire ultrasonic waveform. However, it is still necessary to evaluate the sensitivity of those parameters to thermally damaged concrete. This work aims to assess the behavior and the sensitivity of the following ultrasonic parameters: pulse and group velocities, maximum amplitude, total energy, accumulated energy, and time instants corresponding to 25%, 50%, and 75% of the energy, in detecting changes due to thermal degradation of the concrete. A sample of 39 cylindrical concrete specimens with 100 mm in diameter and 300 mm in length and C25 strength class was used. The sample was distributed into 5 groups heated between 20 and 400 ºC until the internal temperature of the specimens became homogeneous. The groups were cooled inside a muffle furnace until reaching 150 ºC. Subsequently, they were exposed to the ambient temperature and humidity of the laboratory environment for, at least, 24 hours prior to the tests of mass loss, ultrasound, and compressive strength. The results show that the ultrasonic parameters are sensitive to the thermal degradation of the concrete. The pulse velocity, the accumulated energy, and the time instants corresponding to percentages of the energy decrease monotonically as the temperature increases. The group velocity shows significant dispersions, while the maximum amplitude and the total energy increase at 200 ºC. The results led to the conclusion that the pulse velocity is the least sensitive parameter, while the time instants corresponding to 25%, 50%, and 75% of the energy are the most sensitive parameters in detecting changes due to thermal degradation of the concrete.