bluuebunny/crossref_metadata_2025 huggingface dataset:
A Systematic Review on Nanomedicine
Authors: Nawaz Y. , Nazar I. , Ahmad H. , Khan M. S. , Hakeem L. , Saddiqa A. , Ullah M. K. , Shafiaq H. R. , Iqbal K. , Waijad M. , Saeed B.
Published: May 2022

Nanomedicine is used to cure cancer of many tissues such as ovarian cancer and multiple myeloma. With the help of nanotechnology, the probability of failure or rejection of a transplant, an organ is reduced. Nanomedicine is one of the latest and better fields which is used for the treatment of tumors. Some of the methods used to produce nanoparticles are discussed here. Many nanoparticles are used for the benefit of humans. The solvent is subsequently dispersed in a surfactant's aqueous media, resulting in the formation of a film in an instant colloidal suspension called solvent displacement. This method can be used to achieve a pharmacological payload. Supersaturation and precipitation are required for the assembly and stability of drug nanoparticles. Shear and cavitation forces are also used to produce nanoparticles. The milling media is generating shear forces on impact, resulting in nanoparticles, the principle of size reduction. Extrusion is also used to generate nanoparticles. Hydrophobic drugs are converted directly into nanoparticles. The capacity to build nanocores with a wide range of functionalities is another key advantage of the HAylation process (a method to make nanoparticles). Determine medication, metabolism and hepatotoxicity in these models in nanomedicine have the potential to have a significant influence in the field. Red blood cells (RBCs), for example, are sensitive to substantial external flow pressures, and their inherent formability can be used as a biomarker to identify a range of RBC diseases. It is concluded that different nanoparticles are made to treat different kinds of diseases and to make different therapies for cancer etc. Now a day’s nanotechnology is the method that uses nanoparticles to cure diseases and provide a significant treatment approach to humans. Keywords: Nanomedicine, Nanoparticles, Nanotherapeutics, Production of Nanomedicine, Nanotechnology
Variations in Anatomical Position of Vermiform Appendix in Pakistani Population
Authors: Jabeen Hina , . Romaiza , Malik Maria , Kamran Muhammad , Ahmed Hira , Fahim Shazia
Published: May 2022

Aim: To study diversity in position and length of vermiform appendix in human body to manage the patients properly presenting with acute appendicitis. Methods: This is a cross sectional study conducted on 240 bodies. Study was conducted in anatomy department of Dow University of health sciences. Study was completed in one year duration from January 2021 to December 2021. Site and length of vermiform appendix was observed in dead bodies undergoing autopsy. Sample size was calculated using WHO sample size calculator. Consecutive sampling technique was used for sample selection. Data was analyzed using SPSS software (version-20) and chi-square test was applied on the collected data. Result: Total 240 bodies were studied for the anatomical position of appendix, including 156(65%) males and 84(35%) females. Mean age was 34.6 ± 5.2 years with the range of ages as 8-65 years. Mean length of the appendix was 92.6 ± 2.5 mm in men and 85.3 ± 4.7 mm in women. Pelvic position was the most common position of appendix found in 122(50.8%) bodies. Conclusion: High incidence of anterior position of appendix in Pakistani population describe that diagnosis of acute appendicitis can be made sooner and easier in our population with less complications like missed diagnosis, gangrene and perforation as compared to other populations. Key words: Vermiform appendix, Pakistani population, Appendicitis, Anatomical position
To Determine the Efficacy of Antibiotic Prophylaxis in patients Undergoing Flexible Cystoscopy
Authors: Chughtai Umer Javed
Published: May 2022

Background: Flexible cystoscopy is a commonly performed intervention in urology practice. It has both diagnostic and therapeutic value and has an added advantage of being used as an outpatient procedure. However one of the common complication associated with it, is the development of Urinary tract infection (UTI) because of its minimally invasive nature. Aim: To determine the efficacy of antibiotic prophylaxis in patients undergoing flexible cystoscopy. Methods: A randomized control study was performed in total 144 patients selected for flexible cystoscopy. Patients were divided into Group A (Antibiotic group) and Control Group B. Group A received a single dose of Levofloxacin 500mg one hour before procedure, while no antibiotic prophylaxis was given to Group B. Primary outcome was development of UTI, which was assessed by subjective symptoms of UTI, results of urine culture and routine urine examination at 1st week after the procedure Results: After 1 week of procedure, 5 patients (6.9%) in Group A and 7 patients (9.7%) in Group B developed UTI. 3 patients (4.1%) in Group A and 6 patients (8.3%) in Group B developed asymptomatic bacteriuria after 1 week. 64 patients (88.9%) in Group A and 59 patients (81.9%) in Group B did not develop UTI after 1 week of procedure Conclusion: Prophylactic use of antibiotics before flexible cystoscopy has no effect in reducing the frequency of post procedure urinary tract infections Keywords: Urinary Tract Infection UTI), Cystoscopy, Antibiotic prophylaxis
Acute Renal Injury in patient With Severe Acute Pancreatitis
Authors: Mal Pooran , Fareed Ghulam , Seerani Nand Lal , Pathan A. H. , Memon A. S. , Khatti S. N. , Shaikh M. K. , Raza Samar , Shah S. Z. A.
Published: May 2022

Aim: To determine the frequency of acute renal injury in patients with severe acute pancreatitis Methods: It is an observational research where patients coming at tertiary care hospital analyzed as severe acute pancreatitis of either gender were examined. Acute pancreatitis was determined when patients introducing to have pain in abdomen, ascend in serum amylase or potentially lipase > multiple times of ordinary reach and radiological discoveries reminiscent of acute pancreatitis. Acute kidney injury (AKI) was named when individuals with past ordinary renal capacity created decay of renal capacities with ascend in creatinine >2 mg/dl with decrease in urine output to under 0.5mg/kg/hr for 6 hours or more. Results: In our study out of fifty patients of severe acute pancreatitis 20 (40%) were males and 30 (60%) females, 15 women had history of gallstones while the history of alcohol was observed in 10 males and 02 females. The mean age ± SD for whole population is 58.85 ± 8.52. The pain abdomen was present in all patients followed by vomiting in 80%, jaundice was present in 30% cases and fever in 28%. The acute kidney injury has been detected in 32 (64%) of patients and 16 (32%) patients required renal haemodialysis (replacement therapy). The mean ± SD of hemoglobin (g/dl), WBC (x103 cells per cumm), serum potassium, urea, creatinine and bicarbonate for AKI population is 9.52±3.21, 27.85±10.95, 5.63±2.73, 268±20.85, 12.94±8.53 and 15.73±92.21. The mean ± SD of days of kidney insult and haemodialysis sessions for AKI population is 12.75±96.62 and 6.86±4.85 while the frequency (and %) of circulatory failure and deranged INR have been observed in 12 and 21 AKI patients. Conclusion: AKI is an incessant complication of acute pancreatitis and normally creates after the malfunction of different organs. Keywords: Acute renal injury, Acute renal failure and Acute pancreatitis.
Prevalence and Associated Factors of Psychosocial Impact of COVID-19 Pandemic among different population groups in Lahore, Pakistan: a cross-sectional study
Authors: Fatima Kiran , Mir Nazia , Fatima Sundus , Ali Hassan , Ch. Saadia
Published: May 2022

Background: COVID-19 pandemic presents a consequential threat to individual’s mental health in addition to obvious health-related impact. Aim: To focus on prevalence as well as related factors of psychosocial impact of COVID-19 in Lahore, Pakistan. Methods: Our study design was analytical cross-sectional, and study population comprised 382 participants including healthcare workers, teachers, students, and household members. We used non-probability convenience sampling method. We built a structured self-administered questionnaire for collection of data and psychological impact was measured with Impact of Event Scale-Revised (IES-R). Results: Independent factors related to psychological impact were identified using bivariate logistic regression and all significant factors at p-value 0.25 were processed using multivariate model. AORs with 95% CIs were used to assess magnitudes of associations. Prevalence of psychological impact in Pakistan is 53.4%. Being female (β=1.517; AOR=4.561; 95%CI: 2.838-7.329)and covering mouth when coughing and sneezing (β=0.486; AOR=1.626; 95%CI: 1.012-2.612)are significantly associated with psychosocial impact after logistic regression. Prevalence of psychological impact in Pakistan is very high. Conclusion: Henceforth, policy makers need to consider psychological issues while planning pandemic-related interventions. Keywords: COVID-19, psychosocial impact, prevalence, convenience sampling
Frequency of Complete Heart Block in Patients with Acute Inferior Wall Myocardial Infarction
Authors: Ullah Zia , Khan Ibrar , Khan Wajid , Khan Mujeeb Alam
Published: May 2022

Background: Acute MI is the leading health issue globally affecting many lives. Aim: To determine the frequency of complete heart block in patients with acute inferior wall myocardial infarction. Study Design: Cross-sectional study. Methodology: All newly diagnosed inferior wall MI patients were included. Detailed history followed by detailed clinical examination was done. ECGs were done. Complete heart block was evaluated. It was considered as third degree AV block and was diagnosed when there was no AV nodal conduction and the P wave was completely dissociated from the QRS complexes. All this information was recorded on Performa. Data was analyzed using SPSS version 25. Cardiogenic shock was stratified among age and gender by applying chi square test. Results: Age as mean ± SD was 62 ± 8.04 years. Enrolled males were 59% while females were 41% in present study. Results showed that 19% patients had complete heart block while 81% were without it. Conclusion: It was concluded that frequency of complete heart block was high (19%) in patients with inferior wall MI Keywords: Complete Heart Block, Myocardial Infarction and Frequency
Effects of Metformin and N-Acetylcysteine on Dyslipidemia in Streptozotocin-Induced Diabetic Rats
Authors: Bajwa Novera Sohail , Sadaqat Saveela , Khan Wajahat Ullah , Mohsin Mehwish , Memon Mahak , Aslam M. Waqar , Masud Rizwan
Published: May 2022

Background: Diabetes is a chronic health issue globally that has a high incidence. Aim: To see the effects of metformin and N-acetylcysteine on dyslipidemia in streptozotocin-induced diabetic rats. Study Design: Randomized controlled trial. Methodology: A total of 25 rats were divided into 05 equal groups. Diabetes was induced into rats by streptozotocin (35 mg/kg) single doze (i.p). Rats having blood sugar >300 mg/dl after 48hrs were considered as diabetic. Negative and positive control groups were fed on standard diet. Treatment groups were given Metformin, N-acetylcysteine and combination of Metformin and N-acetylcysteine respectively for 4 weeks. Groups were compared for lipid profile thus efficacy of treatment given was evaluated. SPSS 25.0 was used to analyze the whole data. The difference between all the groups was analyzed using One-Way Analysis of Variance (ANOVA). Results: There was significant improvement in a treatment group that received both Metformin plus N-acetylcysteine while other treatment groups had little improvement. Conclusion: It was concluded that dyslipidemia was significantly reduced by use of N-acetylcysteine in combination with metformin among diabetic rats. Keywords: Diabetes Mellitus, Dyslipidemia, Metformin, N-acetylcysteine and Streptozotocin.
Женщина в системе управления в контексте армянской действительности
Authors:   Институт археологии и этнографии НАН РА, Погосян Светлана
Published: May 2022

Цель данной работы – изучение гендерного поведения армянских женщин в системе управления и выявление традиционных и новых гендерных тенденций в идеальных и реальных плоскостях. Работа основана на этнографических наблюдениях и полевых этнографических материалах. За последние 20 лет социальные изменения повлияли также на внутрисемейные и межполовые отношения. Имела место некоторая переоценка ценностных ориентаций. При этом на фоне сильного влияния общественного мнения традиционный стереотип полового поведения переосмысливается с трудом. Среди носителей современной культуры сохранились своеобразные представления о поведении мужчины и женщины, их вовлеченности в систему управления. И сегодня в армянской действительности многие женщины отказываются от профессиональной карьеры, подчеркивая семейные интересы, Среди женщин-чиновников есть такие, которые не претендуют на более высокий социальный статус, так как считают, что эта сфера преимущественно «мужская». Вместе с тем среди девушек и молодых женщин наблюдается тенденция к быстрому продвижению по служебной лестнице.
Արվեստի սահմանների խնդրի շուրջ. «արվեստի աշխարհ» հայեցակարգը
Authors:   ՀՀ ԳԱԱ փիլիսոփայության, սոցիոլոգիայի և իրավունքի ինստիտուտ, Արզումանյան Սվետլանա
Published: May 2022

Արվեստի սահմանների հստակեցման անհրաժեշտությունը, այն է՝ նրա տարբերակումը ոչ արվեստից, ժամանակակից փիլիսոփայության կարևորագույն խնդիրներից է։ Դրա լուծմանն էր ուղղված ամերիկացի հայտնի փիլիսոփա Արթուր Դանթոյի «արվեստի աշխարհ» (artworld) հայեցակարգը, որում առաջարկված էր միմեսիսի սկզբունքի այլընտրանքը։ Հաշվի առնելով ժամանակակից արվեստի երկիմաստ դրսևորումները, որոնք հանգեցնում են դրա սահմանների ընդլայնմանը, այս հայեցակարգը որոշակի հիմքեր է տալիս հասկանալու արվեստի գործի և առօրյա օգտագործման առարկայի էական տարբերությունը՝ թույլ տալով կողմնորոշվելու ձևավորված անսովոր մշակութային իրավիճակում:
Структура и составляющие понятия «духовность»
Authors:   Институт Министерства внутренних дел Туркменистана, Мятиев Хандурды
Published: May 2022

На сегодняшний день несмотря на наличие достаточного числа работ, посвящённых детальному определению понятия «духовность», формулируемые в них гипотезы остаются различными по своему характеру и содержанию. В одних из них категория «духовность» отождествляется с понятиями «душа», «психика», в других же гипотезах «духовность» идентифицируется с категорией «сознание». Духовность проявляется как понимание, отношение личности к своему окружению, внешним событиям, явлениям, действиям, взаимодействию, как диалог между ними и «Я» человека. Следует различать разные виды духовности, с преобладанием этического, эстетического и интеллектуального уклона. Этический аспект духовности рождается в контексте поиска высшей истины, добра, где нравственные помыслы выступают основным двигателем духовной жизни человека. Эстетическое восприятие мироустройства не ограничивается категорией красоты как элемента искусства, а распространяется на повседневную жизнь, сферу деятельности, алгоритм поведения, образ мышления. Интеллектуальное же восприятие отражается на сфере поиска истины, т.к. знание является главным результатом мышления, который может трактоваться как продукт духовности, направленный на реализацию реального культурного потенциала. Эстетические, морально-нравственные и мыслительные аспекты духовности находятся в тесной взаимосвязи, в равной степени способствуя развитию креативных задатков личности, ее духовно-творческой деятельности, осознанию и глубинному пониманию глобальных ценностных установок и тенденций.
Evaluation of requirement of extraction of a second maxillary primary molar in 3 to 5-year-old children
Authors: Shreenidhi S , Jeevanandan Ganesh , Govindaraju Lavanya , Maganur Prabhadevi C , Vishwanathaiah Satish
Published: May 2022

Background: The extraction of primary teeth is a major problem in developing countries. They are given little or no attention because they are thought to shed off on their own, resulting in significant difficulties such as crowding and malocclusion. Aim: The current aim of this study is to study the requirement of extraction of the second maxillary primary molar in 3 to 5-year-old children. Materials and Methods: A total of 136 children from the age group of 3-5 years who had undergone extraction of the second maxillary primary were collected from the DIAS record. The data were clubbed together and the results were analyzed using SPSS software the Pearson Chi-square test was done to find the sign where the p-value was kept <0.05 as the significance level. Results: The results show that 48.62% requirement for extraction is due to caries, 15.42% due to trauma, 15.02% due to mobility, 7.15% due to root resorption, and 13.44% due to other reasons. Conclusion: The study concludes that despite the improvement in pediatric oral health, caries are found to be the main reason for extraction.
comparative study of iliotibial band tenodesis for extra-articular augmentation of ACL reconstruction using staple versus interference screw
Authors: Attalah Mahmoud Mohmmed Ahmed , Ahmed Ahmed Abdalaziz , Rashwan Amr Samir , Mohmmed Moustafa Raafat , Abdelaziz Mahmoud Ahmed
Published: May 2022

Background: Rotational laxity has been demonstrated to persist, even in the face of a well-performed Anterior Cruciate Ligament (ACL) reconstruction. The iliotibial band (ITB) has also been shown to have an impact on the control of anterolateral rotational laxity. In particular, recent research would suggest that the capsulo-osseous layer of the ITB, is a major contributor to anterolateral rotational control. Methods: From December 2018 to December 2020, a prospective randomized (simple randomization) analytical clinical study was done to compare the functional outcome of group of patients undergoing ITB for extra articular augmentation of ACL Reconstruction using staple versus group of patients using interference screw. Results: Upon comparing the postoperative, the primary finding is there was significant improvement of pivot shift in both groups with (100 % grade A pivot shift) in group A and (85 % grade A pivot shift) and (15% grade B pivot shift) in group B. So, the primary finding in this study is significant rotational control. The secondary finding is there was statistically significant difference in the postoperative IKDC objective score between the 2 groups (p= 0.004).
Analysis of moderate subclinical hypothyroid patients with homeostatic model assessment-Insulin resistance
Authors: Pradeep B J , Baghel Manisha , Sharma Bindu , Modala Sudhir
Published: May 2022

Aim: Homeostatic Model Assessment -Insulin Resistance- 2 test findings in people with mild hypothyroidism should be analyzed. Introduction: Hypothyroidism is associated with an increased risk of cardiovascular disease and alterations in blood lipidshave also been related to subclinical hypothyroidism. Treating hypothyroidism with levothyroxine (LT4) may help to improve lipid profiles and heart health, particularly in those with a wider deviation from the normal and higher blood TSH levels. Materials and Methods:There was a wide range of TSH levels among the study's participants, all of whom were between the ages of 20 and 45 and had never been diagnosed with thyroid disease. The study also included 50 people who had recently been diagnosed with moderate SCH but had not earlier been diagnosed with thyroid disease. Results: The glucose metabolism and insulin resistance are strongly influenced by thyroid hormones. Thyroid hormones. Participants in SCH were found to be more likely to be overweight or obese than those who did not participate in the research. TSH (r = 0.290; P\0.01) and LDL (r = 0.210; P\0.052) were shown to be significantly related in this study. SCH individuals had considerably higher LDL-cholesterol levels, according to this research.
Vitamin D status in children with Cerebral palsy
Authors: Kumar Raj , Kumar Ganesh , Runu Ritesh , Gupta Anand Kumar , Sharma Deepak Kumar , Shekhar Ravi
Published: May 2022

Background: Cerebral palsy(CP) is presently defined as a group of permanent disorders of the development of movement and posture, causing activity limitation, that are attributed to non-progressive disturbances that occurred in the developing fetal or infant brain. Low vitamin D levels in children with CP are also associated with decreased muscle strength, balance, muscle pain, paresthesias, and poor muscular coordination. Materials & Method: It is the Prospective observational cross-sectional study. The patients in the study group were of both sexes and aged 6 months to 12 years. All children apart from general tests underwent investigations for serum calcium total {By an automated analyzer}, serum phosphorus {By an automated analyzer}, serum alkaline phosphatase (SAP) levels {By an automated analyzer} and 25 OH vitamin D level {By CLIA (chemi luminescence immunoassay) method}. Results: Total 141 Children who satisfied inclusion and exclusion. Male children were 96 (68%) whereas female were 45(32%).The distribution by the CP type was Quadriplegia 44.0%, Diplegia 34.8%, Hemiplegia 7.1%, Monoplegia 1.4%, Hypotonic 2.1%, Dyskinetic 0.7%, Mixed 0.7%, Evolving CP 9.2%. Ambulatory CP children were 60 (42.5%) and non ambulatory were 81 (57.5%).
Drug timing in glaucoma
Authors: Resheed Wesen Abdulaziz
Published: May 2022

Most ptaient going through distribution Of their drug over day and night baours with  lorg interwal of few hours without adding new treatment get benefit from trail by improving their symptoms of eyea chpain and by about 1 line avarge imporving of there vision and their life quality. Widseparation interval by about 4 hours between different antiglucoma drug is benificial to control Iop flactuationg.
Usage of drones as a medical applications
Authors: Tiwari Shikha
Published: May 2022

Utilizing drone airplane to convey medical care also other wellbeing related administrations is a moderately new use of this innovation in North America. For wellbeing specialist co-ops, drones address a possible means to expand their productivity also capacity to offer types of assistance to people, particularly those in challenging to arrive at areas. This paper presents consequences of a perusing audit of examination writing to decide how robots are utilized for medical care  also   wellbeing related administrations in North America,  also how such applications represent human working  also machine configuration factors. Information were gathered from PubMed, CINAHL, Scopus, Web of Science, also IEEE Xplore utilizing a square quest convention that joined 13 equivalents for "robot" also eight wide terms catching medical care also wellbeing related administrations. 4,000 600 and-65 reports were recovered, also   following a title, conceptual, also full-text screening method finished by all creators, 29 records were held for investigation through an inductive coding process.
work on new method to find initial basic feasible solution of transportation problem in contrast to existing methods
Authors: Shahi Shweta , Henry Vishal Vincent
Published: May 2022

In the present paper, we focused on finding an initial basic feasible solution for transportation problems. The new method is compared to four different proposed mean methods namely, Proposed Arithmetic Mean (PAM), Proposed Harmonic Mean (PHM), Proposed Geometric Mean (PGM) and Proposed Quadratic Mean (PQM) methods along with existing traditional methods like North West Corner Method (NWCM), Least Cost Method (LCM) and Vogel Approximation Method (VAM). Also, the deviation percentage of the outcomes has been figured out in contrast to distinct methods. The approach thus developed, involves elementary arithmetic and statistics, which could be of keen interest even for beginners and is beneficial to decision makers dealing with the problem of supply chain as well as logistics. Suitable examples are given for examining optimality and to validate the results obtained.
Analysis of customer churn prediction using machine learning and deep learning algorithms
Authors: Mahalekshmi A , Chellam G Heren
Published: May 2022

The telecommunication industry need a customer churn prediction due to many competitors. The companies also lack of churn prediction to retain the customer. This problem not only affect the growth of the business but also affect the revenues.  To retain the existing customer is very crucial task for the company. A rapid increasing in technology, the various machine learning and deep learning are tools are developed which can be used by telecoms companies to monitor the churn behaviour of customers. In this study, a brief idea on the customer churn problem on various machine learning techniques such as XGBoost, Gradient Boost, AdaBoost, ANN, Logistic Regression and Random Forest are analysed.  Also the various deep learning techniques such as Convolutional Neural Network, stacked auto encoders to predict the customer churn problem are analysed by comparing the models in terms of accuracy.
Comparision of apical leakage between immediate versus delayed post space preparation using various root canal sealers
Authors: Vanapatla Amulya , Tulasi Priya. N , Neethu Nanda. B , Sneha P. , Avinash M. , Tiwari Heena Dixit
Published: May 2022

Aim of the study: The present study evaluated the apical leakage of endodontic sealers after immediate and delayed post space preparation. Methodology: Sixty-six extracted human maxillary incisors with straight root and single canals were selected and decoronated. They were divided into five groups and obturated using three different sealers (AH Plus sealer, Apexit Plus sealer, Bioceramic sealer) respectively. Specimens were longitudinally sectioned and were observed under stereomicroscope. Results were analyzed and tabulated. Results: There was a statistically significant difference between the immediate and delayed post space preparation. Immediate post space preparation showed less leakage compare to delayed post space preparation. Conclusion: Bioceramic Sealer showed the least leakage at different intervals of post space preparation followed by AH Plus sealer.  Apexit Plus showed more leakage among the groups at different intervals.
study of lipid profile (total cholesterol, tgl, ldl) among clinical hypothyroids and subclinical hypothyroids
Authors: Satyapreethi A. , Benerji G. V.
Published: May 2022

Background: Thyroid diseases are the commonest endocrine disorders in the world. Thyroid hormones are among the most imperative humoral factors involved in setting the basal metabolic rate on a long rate on a long term basis in target tissues such as liver, heart. Kidney and brain. The prevalence of subclinical thyroid dysfunction is higher than that of overt thyroid dysfunction. In general hypothyroidism is associated with hyper cholesterolemia mainly due to elevation of LDL –C levels. This study was done on the lipid profile among clinical and sub clinical hypothyroids. Materials and methods: A total of 400 subjects were analyzed to get a total of 50 clinical hypothyroids pts; 50 subclinical and 50 healthy individuals based on their thyroid profile and detailed history. Patients were taken from outpatient department at KIMS and RF with respect to inclusion and exclusion criteria and lipid profile was measured. Results: In hypothyroidism, it was observed that in hypothyroidism, there is hypercholesterolemia, increased triglycerides and LDL levels which is more in clinical hypothyroids compared to subclinical hypothyroids. Conclusion: We conclude that hypothyroidism causes worsening of dyslipidemia, more in clinical hypothyroid than in subclinical hypothyroid patients.
review on properties of stem cells
Authors: Thapak Gourav , Bala Renu , Rathee Goldy , Panghal Sakshi
Published: May 2022

Stem cells are multipotent progenitors constituting a small proportion of the bone marrow and are present in both adult and fetal tissues including adipose tissue, umbilical cord blood, amniotic fluid, and fetal lung. They were first characterized by Friedenstein and colleagues more than 30 years ago and were described as fibroblast-like cells with the property of adhering to plastic when cultured. This property can be used to purify these cells and enables them to expand several-fold in vitro without losing their differentiation capacity. They can differentiate into both mesenchymal and non-mesenchymal cell lineages such as adipocytes, osteoblasts, chondrocytes, tenocytes, skeletal myocytes, neurons, and cells of the visceral mesoderm, both in vitro and in vivo.
Evaluation of serum vitamin D levels in vitiligo patients
Authors: Pradhan Krupasindhu , Patro Sibasish
Published: May 2022

Background: Recent studies have shown that vitamin D has an immune-protective effect. The role of vitamin D deficiency and VDR gene polymorphisms has been established in many autoimmune diseases, including vitiligo, but the results are still controversial. Aim of the study: To evaluate serum vitamin D levels in vitiligo patients. Materials and methods: For the study, we selected 60 clinically diagnosed cases of dermatology vitiligo and 60 controls which consisted of healthy volunteers with matched age and sex. A comprehensive history was obtained from each participant and each case was studied and closely reviewed. Results: The number of males in cases was 34 and the number of females in cases was 26. The number of males in controls was 33 and number of females was 27. The mean age of cases was 34.69 years and mean age of controls was 37.39 years. It was observed that vitamin D deficiency was seen in 51.6% cases and severe vitamin D deficiency was seen in 25% cases. On the contrary, normal vitamin D levels were seen in 66.7 % of controls and deficiency was seen in 26.6% of controls.
Nursing communication skills in preoperative care
Authors: Hadi Masarrah Aqeel , Mohammed Shatha Saadi
Published: May 2022

Nursing communication skills are critical. As most patients have little understanding about the medical procedures, many patients may feel confused about what is happening around them.  Nurses with excellent communication skills can help reassure patients, understand their needs during preoperative care.Objectives: The purpose of this study is to assess nursing communication skills in preoperative care and to look at disparities in nurses' communication skills based on sociodemographic factors.Methods: A descriptive study with a purposive sample of (N=104) nurses was conducted. This sample is distributed throughout two hospitals regarding to the Babylon Health Directorate. The questionnaire consists of )45 (items. The reliability of the questionnaire was verified by conducting a pilot study and submitting it to a list of experts in nursing field. Data was obtained using self-report and a questionnaire, then analyzed using descriptive and inferential statistical methods.Results: The findings revealed that (45.2%) of nurses’ expressed a moderate level of communication skills with the surgical patients. The nurses’ communication skills are significantly associated with their gender (p=0.000), education level (p=0.000), years of experience in surgical wards (p=0.007) and number of training sessions (p=0.000).
study on pandemic: An opportunity for e-commerce players
Authors: Khan Filza , Singh Satish Kumar
Published: May 2022

A new boom for e-commerce is expected worldwide and in the Indian Market in the essential category. This is accelerated during the pandemic leaving the buyers with no other option but procuring things from the online platforms. When strict measures were in place to avoid crowds, the e-commerce players have advantaged by making the order “PAY NOW” rather than what it was earlier in the option of “Cash on Delivery”.   The opportunity in this sector has multiplied with the help of thoughtful technology and effective logistics management. According to Peter Hinsen, we are already ten years ahead of technology. The pandemic has accelerated the pace of technology acceptance. The successful entrepreneurs in the last decade that India has seen have been “Oyo rooms, Your Story, Ola cabs, Paytm, Zomato, Cred, Flipkart, MakeMyTrip, BYJU’s, Big Basket. Though the times are not the same as before the pandemic, businesses and buyers have adapted to the new dictated time. Adaptability is the key. The author has tried to understand how e-commerce has been progressive in this paper.
Impact of welfare measures on the quality of worklife of information technology employees with special reference to Chennai City
Authors: Anitha G. , Sridharan R.
Published: May 2022

In today's competitive market, a corporate organization must focus clearly on providing welfare facilities to workers, since this result in their happiness with the company, which leads to an improved quality of work life. Human resource management plays a critical part in optimizing a member of staff's output and making the most of the company's valuable assets. This goal will help to boost staff performance and passion to reach the tactical business goal. To improve a member of staff's efficiency and motivation by providing better performance management programs, rewards and recognition initiatives, stress management programs, work-life balance programs and excellent quality stability between work and personal life. The primary goal of employee welfare is to improve employees' lives and keep them happy while they work. Job happiness, productivity, job participation, and job enrichment are all factors that go into determining the quality of work life for people and businesses. In Chennai, a research was conducted to determine the many employee welfare activities skillfully performed by various IT sector activities, as well as their influence on the employees' quality of work life.
Deep clustering with convolution autoencoders and edge detection based classifcation and visualization of Alzheimer’s disease
Authors: Nivethitha A. , Baskar D. , Murali L. , Anandaselvakarthik T.
Published: May 2022

Although there is no treatment for ADs (Alzheimer's Diseases), accurate and early diagnosis is critical for both patients and caregivers, and it will become much more vital if disease-modifying medicines are available to prevent, cure, or even halt the illness's course. One of the most active study topics in the medical industry in recent years has been the categorization of ADS using deep learning algorithms. However, most existing approaches are unable to utilise all spatial information, and so lose inter-slice correlation. To avoid this issues in recent works introduces CAEs (convolution auto encoders) based unsupervised learning for classifying ADs from NCs (normal controls), and supervised transfer learning is applied to solve classifications of Ads into pMCIs (progressive mild cognitive impairments) and  sMCIs (stable mild cognitive impairments). A gradient-based visualisation technique that approximates the geographical effect of CNNs (Convolution Neural Networks) decisions were used to determine the most relevant biomarkers connected to ADs and pCMIs. Despite the fact that DLTs (deep learning techniques) perform well, finding optimal performing network structures for certain applications is not easy since it is frequently unclear how network structure affects network accuracies. This can be solved through hyper parameter tuning of DLTs.
analytical study of health status of adolescent children of various schools of greater Mumbai
Authors: Gill Sonica
Published: May 2022

The World Health Organization (WHO) considers “adolescence” as the period between 10-19 years of age, which generally encompasses the time from the onset of puberty to the legal age of majority. Adolescence is a stage of rapid transition from childhood to adulthood. The concept of health of children has been raised in the World bodies, and article 24 of the United Nations Convention on the Rights of the Child, mentions that children have the right to be as healthy as possible. The study provides insight into the health status of adolescent children of SSC, CBSE, and ICSE schools of Greater Mumbai. The researcher intended to know whether there were any differences or similarities in the Health Status between SSC, CBSE, and ICSE Schools Students of Greater Mumbai. Total 3000 {1000 SSC (500 boys + 500 girls), 1000 CBSE (500 boys + 500 girls) and 1000 ICSE (500 boys + 500 girls)} schools students were selected as sample for the research study. The study conducted was a survey in nature and under the heading of Descriptive Research. The questionnaire used EQ-5D-3L Questionnaire by Mandy van Reenen/Mark Oppe (April 2015).
Comparative evaluation of surgical management using minimal invasive stabilization of the distal femoral fracture using screws and plates for appendage compression
Authors: Sharma Shalinder Kumar , Malik Irfan , Sharma Rahul
Published: May 2022

Background: Management of the fracture of the femur has also been a controversial subject in the literature, and recently, this management has been attributed to the minimally invasive techniques and indirect reduction. Aims: The present clinical study was conducted to comparatively evaluate the results following surgical management using minimal invasive stabilization of the distal femoral fracture using screws and plates for appendage compression. Material and methods: The present study included and retrospectively analyzed subjects with the fracture of the distal femur. From their past medical records, variables assessed were postoperative bleeding, operating time, implant type used, mechanism of injury, fracture form, gender, and age. For comparison of the useful, radiological, and anatomic outcomes of each technique, the Neer scale was used. Results: At 1-month flexion mean was higher in group I with 33.28±4.63 compared to Group II here flexion was 29.91±2.96. This was statistically non-significant with p=0.96.
Randomized controlled trial to determine analgesic efficacy of intrathecal 1% 2- chloroprocaine with or without fentanyl during elective caesarean section
Authors: Varghese Kiran K , Brindha R , Sabapathy V A , Thilaak Prabhu
Published: May 2022

Background-Preservative free 1% 2‑chlorprocaine is a short acting local anaestheticagent appropriate for day care surgical techniques. Potentiation of analgesic accomplishment of intrathecal local anesthetics by the addition of opioids is well recognized. Objectives- To investigate the effect of intrathecal fentanyl as an adjuvant to 1% 2‑chloroprocaine (2‑CP) in parturients undergoing elective lower segment caesarean section (LSCS). Methods: A prospective randomized double blindstudy was performed on 150 healthy, term parturients planned for elective LSCS, divided into two equal groups. The group C1 received 1% preservative‑free 2‑CP 3 ml (30 mg) + 0.5 ml normal saline and group C2 received 1% preservative‑free 2‑CP 3 ml (30 mg) + 0.5 ml fentanyl (25 μg) with a total volume of 3.5 ml intrathecally in both groups. The duration of sensory blockade, duration of motor blockade, maximum height of sensory block, haemodynamic parameters, quality of block, neonatal outcome, patient satisfaction and any side effects were recorded. Results: There were no significant differences in demographic characteristics, haemodynamic parameters, onset of sensory block, and onset of motor block and duration of motor block between the groups.
Scopes and barriers for effective management of biological hazard induced pandemic
Authors: Nath Dipak , Nath Ruma Deb
Published: May 2022

Biological hazard induced pandemic events have become recurring phenomena in this globe. Time after time, human civilization is facing crisis due to occurrence of pandemic like situations. It is difficult to precisely assess the risk factors associated with newly originated virus induced pandemic due to unknown characteristics of such virus.  Unlike many natural hazards, there may not be any early warning signs for such biological hazard induced pandemic events.  So, pandemic management is a complex job having multidimensional aspects. In-depth analysis of significant past pandemic events is necessary to understand the scopes and barriers of pandemic management. The ongoing global crisis pertaining to COVID-19 induced pandemic has similarity to that of Spanish Flu induced disaster event of 1918, in terms of characteristics, modes of transmission, and damage potentials of health hazards. Careful review of crisis situations related to Spanish Flu and COVID-19 originated pandemic events may be useful to formulate holistic strategy for pandemic management and damage mitigation.  In this paper, an attempt has been made to understand the hazard-vulnerability profiles of both Spanish Flu and COVID-19 induced disaster events and highlight probable scopes and barriers pertaining to management of biological hazard induced pandemic events.
ECG signal PQRS detection and comprehensive estimation of signal noise
Authors: Amhia Hemant , Wadhwani A. K.
Published: May 2022

Automated bioelectric signal analysis has an important application in the wisdom medical care. In this work, we focus on ECG-signal and address a novel approach for cardiac arrhythmia diseases classification. We designed a novel analysis framework which extract different feature transformations from ECG signals. And we trained the ANN model for multi-feature to obtain the prediction. Finally, we tested our approach on the public database of MIT-BIH arrhythmia. And the results of experiments on the database demonstrate our model has better classification performance than other approaches.
Comparative evaluation of the advantages of single-layer closure to en-masse closure in the surgeries of the abdomen
Authors: Kumari Soni , Parashar Anant
Published: May 2022

Background: Closure of the abdomen is a vital step in abdominal surgeries, with advent of newer techniques for suturing and suture material, repair technique, and incision, which has evoked great interest among surgeons.Aim: To comparatively evaluate the advantages of single-layer closure to en-masse closure in the surgeries of the abdomen.Subjects and Methods: 64 subjects randomly divided into two groups of 32 subjects each where Group I was closed with single-layer closure, and, Group II with layered closure. The subjects were assessed postoperatively on days 1, 3, 7, and 10, and were compared for burst abdomen, infection, and operative time. The follow-up was done every month for first 3 months and then after 6 months.Results: Wound infection incidence was higher in Group II (layer closure) compared to Group I (mass closure). In the Group I, elective surgery group, wound infection was seen in 1 subject with an abdomen burst. In emergency surgery group, wound infection was seen in no subject with abdomen burst and subjects without abdomen burst. In Group II (layered closure), in elective surgery group, wound infection was seen in 5 study subjects.
Advance cellular networks (4G, 5G, 6G)
Authors: Swamy Anjali
Published: May 2022

Over the last several decades, the need inasmuch as wireless communication has skyrocketed. The next generation appropriate to communication, known as 5G, will soon be in widespread use throughout the globe. It is predicted that the sixth-generation (6G) wireless communications system would be deployed between 2027 also 2030 with complete support inasmuch as artificial intelligence. More capacity greater data rate also lower latency; better security also enhanced quality appropriate to service. (QoS) are some essential challenges that  need  towards be solved beyond 5G, compared  towards the 5G system. in this study, the future network architecture appropriate to 6G wireless communication is described. Al, terahertz communication also wireless optical technology is some appropriate to the emerging technologies discussed in this article. Other topics coved include block chain, three dimensional networking also quantum communications, unmanned aerial vehicles, cell free communication, integrated wireless information also energy transfer, integrated sensing also communications, integrated wireless information also energy transfer, integrated sensing also communication, dynamic network slicing, also backscatter coherence. In addition, 6G communication requirements also potential technologies inasmuch as envisaged applications are discussed. On the way towards accomplishing this aim, we’ll discuss possible roadblock also new paths inasmuch as study.
Distinctive behavioral characteristics of outstanding students in the light of Triarchic theory of intelligence from the point of view of students and their teachers
Authors: Sabbah Suheir Sulieman , Aldin Ablah Mustafa Hasan Abd
Published: May 2022

The study aimed to identify the distinctive behavioral characteristics of outstanding students in light of the Triarchic theory of intelligence from the point of view of students and their teachers. The sample consisted of (51) students, 34% of whom were excelling in the sixth and eighth grades, as well as (76) teachers, and for this purpose, the distinctive behavioral characteristics of outstanding students scale was used, in addition to conducting a focus interview with teachers. The results of the study indicated that the level of behavioral characteristics from the point of view of students came significantly by 82.01%, where both the domains of creative ability and applied ability were ranked first, followed by the domain of analytical ability. As for the level of distinctive behavioral characteristics of outstanding students from the point of view of teachers, it came significantly by 77.29% and in this order; analytical ability, then applied ability, and finally creative ability, and these results corresponded to the corresponding data collected from teachers, but the ranking of these domains differed, where analytical characteristics were ranked first, then applied, and finally creative.
Phenotypic and genotypic detection of Enterobacter spp isolated from clinical cases
Authors: Yassir Sara Mohssin , Zaid Basaad Abd
Published: May 2022

Enterobacter Spp an opportunistic bacteria that causes a variety of infections in hospitalized patients around the world, can resist  -lactams primarily by generating the CTX-M enzymes and AmpC  -lactamase enzyme. The spread of ESBL is a serious public health concern, and infections with ESBL-producing organisms have been linked to negative outcomes. We looked at the prevalence and screening criteria for extended-spectrum-lactamases (ESBLs) in Enterobacter spp. that produce AmpC. The 20 isolates (18 Enterobacter Cloacae Complex,2  Enterobacter Aerogenes) isolated from clinical cases . We performed polymerase chain reaction for Ampc and blaCTX-M. The Ampc was detected in 12 of 20 isolated, and the blaCTX-M was detected in 11 of 20 isolated.
Comparison of diagnostic accuracy of transcutaneous bilirubin at different sites with serum total bilirubin measurement in preterm neonate
Authors: Amneenah Abdullatif Mohammed , Elzahaf Raga A. , Shahat Fayiza Ibrahim
Published: May 2022

Background: Transcutaneous bilirubin measurement (TcB) is widely used in term babies, but its effectiveness as well as the suitable site for (TcB) measurement in preterm babies still debated. Aim and Objective: To compare the diagnostic accuracy of different transcutaneous bilirubin sites with serum total bilirubin measurement in preterm neonate. Methods: This prospective comparative study was carried out in special care baby unit at Alwahda teaching hospital-Derna-Libya. (102) preterm infants (gestational age less than 37 weeks) in whom clinical jaundice was significant mandating TSB measurement were included in the study. Study subjects who met the inclusion criteria were chosen consecutively. All the measurements were carried out within first postnatal week. Transcutaneous bilirubin was measured from four sites: forehead, sternum, abdomen and interscapular region and within 30 min of TSB measurement. Results: Correlation coefficients of transcutaneous bilirubin measured from forehead, sternum, abdomen and interscapular sites were 0.69, 0.70, 0.67 and 0.69 respectively. TcB measured from all the four sites correlated significantly with serum bilirubin (p < 0.001), but the correlation was best at abdominal site. Conclusions: Transcutaneous bilirubin measurement is an acceptable method for identification of hyperbilirubinemia requiring treatment in preterm newborns.