bluuebunny/crossref_metadata_2025 huggingface dataset:
Magmatic immiscibility and the origin of magnetite-(apatite) iron deposits
Authors: Pietruszka Dorota K. , Hanchar John M. , Tornos Fernando , Wirth Richard , Graham Nathan A. , Severin Kenneth P. , Velasco Francisco , Steele-MacInnis Matthew , Bain Wyatt M.
Published: October 2022

The origin of magnetite-(apatite) iron deposits (MtAp) is among the most contentious issue in ore geology with competing models involving purely hydrothermal to magmatic processes. We study here melt inclusions trapped in plagioclase phenocrysts in andesite hosting the emblematic MtAp mineralization at El Laco, Chile. Our high-resolution study reveals that individual melt inclusions preserve complex processes of melt immiscibility including the separation of Si- and Fe-rich melts, the latter hosting other Cu-sulfide, phosphate-rich, and C-O-HFSE-rich residual melts. This assemblage is a small-scale analogue of the ore mineralization and establishes the missing link between silicate and Fe-P-rich melts which subsequently produce extrusive magnetite. These results strongly indicate that El Laco mineralization derives from crystallization of Fe-P-rich melts providing insight into the formation of similar deposits elsewhere.
Implementation of triply periodic minimal surface (TPMS) structure in mesenchymal stem cell differentiation.
Authors: khan Bangul , Kumar Sanjay
Published: October 2022

Tissue engineers have recently been interested in triply periodic minimum surfaces (TPMSs) for use in creating biomimetic porous scaffolds. Improved cell attachment, migration, and proliferation may be achieved with TPMS scaffolds because of its many benefits, such as a high volume to surface area ratio, reduced stress concentration, and enhanced permeability compared to conventional lattice architectures. Some of the crucial tissue-specific parameters, such permeability, Elastic modulus, and pore size, have been considered by the designers of various TPMS scaffolds described in the literature. These days, triply periodic minimum surface (TPMS) is seen as a leading option for building porous structures due to its smooth edges, fully integrated porous architectures, and mathematically adjustable geometry. Many benefits of TPMS, however, are not being properly used in ongoing studies. This study suggests the future direction of the TMPS in the perspective of the mesenchymal stem cell differentiation to overcome many shortcoming which was faced by the researchers.
Ore mineral formation stages of the Sredniy site (Mnogovershinnoye deposit)
Authors: Maltseva G. D. , Yakhno M. V. , Ivanova R. N. , Burueva G. N.
Published: October 2022

The Mnogovershinnoye gold deposit (Khabarovsk Territory, Russia) today is a significant industrial facility, which features extension additions as a results of additional in-mine exploration of deep horizons and identification of new objects within the ore field. The purpose of this work is to study the formation stages of ore minerals of one of the deposit sites as well as to identify the mineralogical and structural-textural features of ores. The methods of mineralogical and petrographic study of the material composition of ores are widely used in geological practice and allow to determine the material features of the studied objects as well as describe the ore formation process. The study of ore types was carried out using an Olympus BX51 microscope. Field observations performed by the authors served the base for the mineralogical and petrographic study of ore samples and host rocks of the Sredniy site of the Mnogovershinnoye deposit, which led to a slightly different understanding of formation stages of ore mineralization of this section of the deposit. The study revealed at least three formation stages of the material complex of this site of the deposit. The first stage is a magmatic one. It characterizes with the formation of pyrite of the first generation. The second stage is an ore hydrothermal one, as a result of which the gold-sulfide mineralization was formed including pyrite of the second generation, chalcopyrite, magnetite, kustelite. Gangue quartz was formed at the end of the second stage together with such ore minerals as pyrite, chalcopyrite, magnetite, and an insignificant amount of kustelite and native copper. The third stage is an exogenous one, during which substitution and oxidation structures were formed with iron hydroxide evolution. The studies of the ores of the Mnogovershinnoye deposit have shown once again the presence of polysulfide multistage mineralization, which had been developing in close connection with the magmatic process. Knowledge about the deposit formation stages is an integral part of the creation of geological and structural models of the deposit, which are necessary to increase the efficiency of geological exploration within the studied objects.
Producing gold nugget simulants using copper alloys
Authors: Sorokina V. E. , Konstantinova M. V.
Published: October 2022

Today the imitations of gold nuggets are highly promising materials in conceptual jewelry design. The manufacturing technology of these materials is based on melted brass casting in a cooling liquid. The purpose of this research is to identify the most favorable technological processes to obtaining high-quality simulants of gold nuggets. The article presents the results of the experimental studies of CW508L brass. The most favorable technological parameters have been identified. They include the melt temperature up to 970±5 °C and use of water with the temperature not higher than 20–25 °C as a cooling liquid. Adherence to the specifications allows to obtain the casts, which superficially resemble natural gold nuggets found in alluvial gold deposits. The casts’ intricate shape and uneven relief providing this resemblance are due to the specific crystallization conditions of brass that differ from the crystallization conditions under conventional casting. The research involved the analysis of the chemical composition of the alloy samples before tests and the samples obtained after casting. After processing the alloy has featured an insignificant decrease in the zinc percentage, and an increase in the impurity content (silica, sulfur, iron, and chrome). The metallographic analysis of the initial sample of CW508L brass has shown a single-phase microstructure that is a solid solution of zinc substitution by copper. The similar study of the casts obtained in the experiment has shown the presence of a β-phase in their structure (along with an α solid solution) that is a CuZn-based solid solution having a positive effect on brass mechanical properties. This microstructure is typical of the alloys undergone accelerated cooling that qualitatively changes the process of melt converting into a solid substance.
Geoecological conditions of the Khabarovsk agglomeration for construction waste disposal
Authors: Kulakov V. V. , Pasichnikov V. E.
Published: October 2022

This research is aimed at the geoecological assessment of the territory of the Khabarovsk agglomeration in terms of location possibility of construction and demolition waste or recycling of the latter, as well as the environmental impact of the waste. The annual volume of construction waste generation in Khabarovsk is 407.5 thousand tons (326.9 thousand m3). All waste from the construction sector of the Khabarovsk agglomeration is sent to landfills. The study territory distinguishes two areas: the one of the flood plain and above-floodplain terraces of the Amur river in the western part, which is flooded in the periods of high and catastrophic floods and features unfavorable geoecological conditions, and the area on the right bank of the Amur river in the eastern part of the territory with urban development where the groundwater levels exceed 2 m. In the course of the study, the authors identified the potential locations of the construction waste recycling complex and considered the possibility of arranging a site for temporary storage of raw materials having given the rationale for this choice. The methods applicable in the field of waste recycling under the formation of the construction and demolition waste processing industry are described. The potential of using waste as material resources as well as the environmental aspects of waste recycling in the form of building materials are evaluated. It is noted that by 2030, the carbon footprint will be 116.8 thousand tons of carbon dioxide as a result of waste disposal at municipal solid waste landfills. To reduce the carbon footprint (carbon dioxide emissions) during the construction works involving concrete and bituminous concrete it is justified the use of processed aggregates based on recycled crushed stone. The sites favorable for the placement of construction waste recycling enterprises have been identified during the survey of the city. They are located outside the existing and prospective urban and industrial development, as well as outside the zones of specially protected natural areas.
Using proppant indentation coefficient in design of hydraulic fracturing treatment of oil source rocks
Authors: Nuriev A. A. , Sultanov Sh. Kh.
Published: October 2022

The purpose of the study is the laboratory determination of proppant indentation coefficients depending on the geological composition of the oil source rocks and their application in the design of hydraulic fracturing treatment. The laboratory researches used the core material of oil-producing deposits of the Domanic formation. The indentation of prop pant was carried out on the CTM-100 compression testing machine, in order to eliminate the measurement error, the size of the cells was additionally specified using ADF U300P microscope with the operation capacity either in reflected light or reflected and transmitted light only. As a result, the geological features of the Domanic complex were confirmed: a large content of organic matter was traced on the core material, the bulk of the rock was composed of carbonates with frequent lithological layering. The indentation coefficient of 20/40 proppan were as following: 0.2–0.4 mm in limestones, 0.23–0.45 mm in clay limestones, 0.47 mm for organic matter. The indentation coefficients for 30/50 proppant were as follows: 0.1– 0.5 mm in limestones, 0.13–0.55 mm in clay limestones, 0.47 mm in organic matter. The use of the obtained coefficients in the design of hydraulic fracturing treatment allowed to specify the fixed width of the crack opening that will have a positive effect on the predicted starting well yield under subsequent modeling. The proppant indentation is in direct relationship to the composition of the oil-producing rocks. When using the proppant coefficients it is advisable to pay additional attention to the proppant tracking map. The use of laboratory studies with subsequent modeling in the hydraulic fracturing simulator allows more accurate understanding of the fixed geometry of the crack of the formation fracturing. Estimation of the crack opening width at the stage of hydraulic fracturing design makes it possible to adapt the parameters of formation treatment, which has a positive effect on the lifetime of the crack width as well as on the well yield.
The Lifeworld of Millennial Stage Actors in Metro Manila: A Schutzian Phenomenological Study
Authors: Jalaine Joyce V. Malabanan  , Jose Mari A. Carpena  , Feorillo Petronilo A. Demeterio III
Published: October 2022

Using the phenomenological method developed by the Austrian-American philosopher and social theorist Alfred Schutz, this article studied the lifeworld of millennial stage actors in Metro Manila, Philippines. Lifeworld is the meaning-giving sphere of common sense that is shared by individuals from a given social group. Using the data gathered from key informant interviews with 12 professional actors and five consociates from the said locale, we investigated how these millennial actors started their careers in the theatre industry, how they perceived theatre in general and Philippine theatre in particular, how they experienced the challenges and difficulties in their careers, how they were motivated to persevere, and how they envisioned their long-term future in the same industry. This article contributes to the sparse literature on the lives of contemporary professional stage actors in general, and to the almost non-existent literature on Filipino professional stage actors in particular. Understanding the status and problems of the lives of professional stage actors should be the first step in further improving their plight and in appreciating more their central role in the continued existence of theatre as a cultural practice.
Blogosphere as a New Means of Communication
Authors: Suleymanov E. A.
Published: October 2022

The paper is dedicated to the blogosphere as a means of communication in the conditions of modern media reality. The author states, that the blogs perform not only a function of interpersonal communication, but also an information function, approaching traditional mass media in this vein. They allow to search, distribute and discuss information on any topic, and business or political information is no exception. In this regard, many companies and major players in the global and domestic markets have turned their attention to this tool for interacting with the audience, developing their own social networks and blog sites and actively cooperating with popular bloggers, experts and opinion leaders as part of image building and reputation improvement, countering information challenges, promoting services and products. It is noted that the blogosphere in comparison with traditional media has a number of advantages: mobility, dynamism, nativity, and quick feedback. The possibilities of the blogosphere operating in a unique hyper-genre – a symbiosis of textual, visual and audio information are discussed. At the end, the author substantiates the necessity of studying the role of the blogosphere in the system of business and political communication, the principles and mechanisms of its influence and development.
Socialization of Islam In The Geopolitics of Central Asia
Authors: Makhmutov R. R. , Saliev A. A.
Published: October 2022

The paper examines the socialization of Islam in the context of geopolitical processes with an emphasis on the socio-cultural component of interstate interactions in Central Asia. Based on a review of the current state of the processes of religious socialization and religious policy in the Central Asian republics, the authors conclude that these processes in the countries of the region within the framework of the EAEU are most productive when using new communicative approaches that allow stopping destructive and radical religious trends, rather than hushing them up, or ignoring. The uniqueness of the new socialization of Islam as an unconditional communicative interstate mechanism for containing radical Islamic movements lies in the fact that for the first time an idea is being implemented that involves solving the problem of terrorism and extremism, not related to the ban on religious organizations and the use of force. The authors emphasize the need for a correct, active and consistent use of the religious component in interstate integration interactions in the social space of Central Asia. This is especially important when using digital methods of interaction with actors of social action in the context of hybrid communications and the exacerbation of the geopolitical situation.
Topological states in double monolayer graphene
Authors: Wu Yinghai
Published: October 2022

Motivated by the experiments on double monolayer graphene that observe a variety of fractional quantum Hall states [Liu et al., Nat. Phys. 15, 893 (2019); Li et al., Nat. Phys. 15, 898 (2019)], we study the special setting in which two monolayers have different areas. It has not been considered before and allows us to construct a class of exotic topological states. The elementary excitations of these states do not carry fractional charges but obey fractional statistics. This is in sharp contrast to all previously studied cases, where the two properties are intimately connected and serve as hallmarks of fractional quantum Hall states. Numerical calculations are performed to demonstrate that some states can be realized with realistic parameters.
Joule heating in bad and slow metals
Authors: Glorioso Paolo , Hartnoll Sean
Published: October 2022

Heat supplied to a metal is absorbed by the electrons and then
transferred to the lattice. In conventional metals energy is released to
the lattice by phonons emitted from the Lindhard continuum. However in a
'bad' metal, with short mean free path, the low energy Lindhard continuum is destroyed. To describe energy transfer to the lattice in these cases we obtain a general Kubo formula for the energy relaxation rate in terms of the electronic density spectral weight \text{lm} \, G^R_{nn}(\omega_{k},k)lmGnnR(ωk,k) evaluated on the phonon dispersion \omega_kωk. We apply our Kubo formula to the high temperature Hubbard model, using recent data from quantum Monte Carlo and experiments in ultracold atoms to characterize \text{lm} \, G^R_{nn}(\omega_{k},k)lmGnnR(ωk,k). We furthermore use recent data from electron energy-loss spectroscopy to estimate the energy relaxation rate of the cuprate strange metal to a high energy optical phonon. As a second, distinct, application of our formalism we consider 'slow' metals. These are defined to have Fermi velocity less than the sound
velocity, so that particle-hole pairs are kinematically unable to emit
phonons. We obtain an expression for the energy relaxation rate of a
slow metal in terms of the optical conductivity.
Forming a Culture of Health in the Adult Population
Authors: Kartavtseva Antonina , Mahan'kova Natal'ya , Mahan'kova Polina , Pohorukov Oleg
Published: October 2022

The paper focuses on the terms of health, health culture, and health-preserving technologies. It introduces different interpretations of health and health culture, as well as the factors that contribute to health and those that can harm it. The culture of health is the most important component of human psyche as it characterizes the level of personal development, education, and health promotion. The authors substantiate the necessity of preserving and strengthening health through systematic sports activities. They reviewed relevant publications to prove that only personal health culture can improve social environment and protect people against the negative factors of the modern world. The analysis of practice-oriented approaches to health preservation in adults resulted in a new technology of developing healthy lifestyle skills in women aged 40–60. The article describes the conditions and tools for its practical application and the results obtained with the help of the proposed technology. The authors substantiated the possibility of dissemination of the obtained experience by using this technology in sports clubs and fitness groups.
Teaching Activity in the Context of Digital Education
Authors: Shul'ga Irina
Published: October 2022

The article updates professional skills of a teacher in the context of digital transformation of education. The author actualizes the need for changes in the traditional functions of a schoolteacher. The new functional features include motivation management (pedagogical coaching), designing individual academic road maps (pedagogical design), creating lesson scripts (pedagogical directing), providing pedagogical assistance (personal tutoring), and encouraging positive involvement (pedagogical animation). The article establishes a logical connection between these new professional functions in the teacher's activity and the key principles of digital education. It also offers some new prospect areas in professional teacher training, e.g., theory and methodology of teaching and upbringing in the context of digital education.
Legal Aspects of Forest Export in Soviet and Modern Russia: Comparative Analysis
Authors: Vinnichenko Oleg , Sahibov Karim
Published: October 2022

This article traces the history of forest legislation and timber export from the Soviet Union to this day. The author studied legal acts and historical documents to analyze the possibility of using positive historical experience in the current forest law. This analysis, as well as interdisciplinary and systematic approaches, made it possible to study certain aspects of Russian export activities. This publication represents a theoretical and practical foundation for further research that will cover pre-revolutionary, Soviet, and Russian forestry legislation in the field of timber export. The author believes that contemporary timber export needs the same methods that were applied in the Soviet Union. Their essence was in the strict control, a clear structure of authorized bodies, and various restrictive measures.
Determinan Academic Fraud pada Mahasiswa dalam Mata Kuliah Akuntansi
Authors:   Prodi D-IV Administrasi Bisnis Terapan, Jurusan Administrasi Niaga Politeknik Negeri Ambon, Jl. Ir. M. Putuhena, Rumah Tiga, Tlk. Ambon, Kota Ambon, Maluku, Indonesia, Ardiansyah Ardiansyah
Published: October 2022

This study aimed to determine the effect of learning motivation, learning media, religiosity, rationalization, and academic pressure on academic fraud. Data was collected by distributing questionnaires to students of the Applied Business Administration (ABT) DIV Study Program, as many as 57 respondents. Due to the small number of samples, data processing was processed using the Partial Least Square (PLS) method. The findings in this study indicate that: (1) learning motivation has a negative and significant effect on academic fraud; (2) learning media has a negative and significant effect on academic fraud; (3) Religiosity has no effect on academic fraud; (4) Rationalization has a positive and significant effect on academic fraud; and (5) academic pressure has no effect on academic fraud. Empirically, this research reveals that religiosity and academic pressure are relative to everyone who can encourage them to do good or bad (academic fraud) depending on other more dominant factors. It suggests recommendations for further research to expand the number of respondents.
Nilai Perusahaan, Manajemen Risiko, Tata Kelola Perusahaan: Peran Moderasi Ukuran Perusahaan
Authors:   Universitas Tarumanagara, Jl. Letjen S. Parman No. 1 Jakarta Barat 11440, Indonesia, Ticoalu Reynold , Januardi Januardi ,   Universitas Tarumanagara, Jl. Letjen S. Parman No. 1 Jakarta Barat 11440, Indonesia, Firmansyah Amrie ,   Polytechnic of State Finance STAN, Jl. Bintaro Utama Sektor V, Bintaro Jaya, Tangerang Selatan, Banten., Trisnawati Estralita ,   Universitas Tarumanagara, Jl. Letjen S. Parman No. 1 Jakarta Barat 11440, Indonesia
Published: October 2022

Penelitian ini bertujuan untuk menguji pengaruh pengungkapan manajemen risiko dan tata kelola perusahaan terhadap nilai perusahaan. Selain itu, penelitian ini juga memasukkan ukuran perusahaan sebagai pemoderasi dalam hubungan pengungkapan manajemen risiko dan tata kelola perusahaan terhadap nilai perusahaan. Penelitian ini menggunakan data perusahaan perbankan yang terdaftar di Bursa Efek Indonesia dengan periode pengamatan 2016 – 2020 dengan total 195 observasi dengan melalui purposive sampling. Uji regresi data panel dengan menggunakan fixed effect model digunakan untuk menguji hipotesis pada penelitian ini. Hasil pengujian menunjukkan bahwa pengungkapan manajemen risiko tidak berpengaruh terhadap nilai perusahaan, sedangkan tata kelola perusahaan berpengaruh negatif terhadap nilai perusahaan. Selanjutnya, penelitian ini juga menemukan bahwa ukuran perusahaan mampu memperkuat pengaruh positif pengungkapan manajemen risiko terhadap nilai perusahaan, namun tidak memperkuat tata kelola perusahaan terhadap nilai perusahaan. Penelitian ini mengindikasikan bahwa Otoritas Jasa Keuangan selalu otoritas pengawas perbankan di Indonesia perlu meningkatkan kebijakan atas pengungkapan manajemen dan tata kelola pada perusahaan perbankan.
Criteria of Law Progress
Authors:   Kazan Innovative University named after V. G. Timiryasov (EIML), Skorobogatov A.V. , Krasnov A.V. ,   Kazan Branch of the Russian State University of Justice, Yusupov A.A. ,   Kazan Institute (Branch), All-Russian State University of Justice
Published: October 2022

The article is dedicated to philosophical and legal research of the criterion of legal progress. Based on the study of content, features and meaning of the legal progress for the development and functioning of the legal reality, the authors conclude that the criterion of legal progress should be considered as a methodological and epistemological instrument that expresses all possible aspects and indicators of making the legal reality perfect. The authors underline the necessity to distinguish the criteria of legal progress and the progress viewed as a social phenomenon generally. Using teleological approach to the study of the criterion, the article states that the ontological criterion of the legal progress mostly expresses the success in the development and functioning of the legal reality. This success depends on the degree of achievement of the goal of the legal progress. The article interprets goals, tasks, mechanism of transformation as a legal criterion. The authors update axiological, subjective, objective criteria of the legal progress. They underline that the criteria of the legal progress have dual nature (subjective and objective). This nature is caused by interpretative peculiarities of this category, the representatives of societies and reflection about different legal interests. That is the reason why they cannot be universal. The legal progress in general is socially and culturally dependent and cannot be examined without a certain historical period of development and the level of legal reality.
Actual Problems of Legal Regulation of Financial Relations
Authors:   Institute of State and Law of the Russian Academy of Sciences, Vasyanina E.L.
Published: October 2022

Modern economic reality requires the formation of new approaches to the regulation of financial relations aimed at ensuring state sovereignty and the resistance of the state's financial system to economic crises of any scale. In the context of the structural restructuring of the world economy caused, on the one hand, by an increase in the gap between the real and virtual economies and, on the other hand, by the transition to a multipolar system of foreign economic relations. A number of paradigmatic positions and attitudes in the field of regulating financial relations are changing, new patterns are being formed, conditions and factors for the development of the financial system of the state. The formation of an effective legal model for the regulation of financial relations that meets modern challenges requires the study of key problems in the financial and legal sphere, identifying the causes and determining ways to resolve them. An analysis of financial legislation and law enforcement practice allows us to state that the problems in the implementation of the mechanism of financial and legal regulation are caused by: the use of alternative legal instruments for regulating financial relations; the implementation of numerous administrative procedures within the framework of the financial activities of the state, leveling the obligatory nature of financial legal relations; internal inconsistency of acts of financial legislation, etc. The development of the theory of financial law and financial legislation should be aimed at finding effective legal means aimed at consistent legislative consolidation of the completeness of the essential conditions of financial obligations, streamlining the system of measures of property liability for violation of financial legislation, working to eliminate internal inconsistency of financial legislation acts, etc.
Norms of Housing Legislation: on the Question of Understanding and Existing in Time
Authors:   Irkutsk Institute (Branch), All-Russian State University of Justice, Suslovа S.I.
Published: October 2022

The article evaluates approaches of doctrines and legal practice to the issue of understanding the term of «housing legislation norm» from the perspective of correlation with the term «civil right norm regulating housing legislation». The article defines the priority while applying the norms the Russian Federation Civil Code and Russian Federation Housing Code in case of their contradiction to each other. The article suggests explaining two situations when the housing legislation norms should have a priority over the civil right norms that regulate housing relations. The first situation is connected to the list of housing relations legally fixed in Article 4 of the Houseing Code of the Russian Federation; the second situation is linked to the direct reference of the civil legislation norms. The author of the article criticizes the approach suggested by the Supreme Court of the Russian Federation when there are the differentiating of the fields of regulating of the criteria of housing evaluation which is viewed as an object of «economic turnover». The article analyses the Supreme Court of the Russian Federation practice in question of setting the peculiarities of the legal regulation of the existing of housing legislation norms in time. The author concludes that the peculiarities of the housing relations can show the exemptions from the common rules when the law is applied in reverse.
The Role of Judicial Auto Technical Examination in the Investigation of Fraud in the Auto Insurance Sphere
Authors:   East Siberian Institute of the Ministry of Internal Affairs of Russia, Usachev S.I.
Published: October 2022

Modern market of auto insurance is rather imperfect and has numerous ways of gaining financial benefit illegally. That is the reason why fraud in the field of auto insurance is a very common crime in this field. Methods of investigating, solving and preventing of fraud in the field of auto insurance has been connected to the use of special knowledge for a long time because this aspect is indisputable help in the forming of evidence base. Practice shows that the most common procedural form of the implementation of special knowledge is the appointment and production of various examinations and studies. This circumstance is justified because forensic examination helps gain enough reliable evidence needed for investigating and solving crimes. Forensic examination is the main form of applying special knowledge in fraud investigating in the field of auto insurance. The article analyses forensic auto technical examination, its peculiarities and applications while investigating frauds in the field of auto insurance. The article characterizes main tasks and objects of investigation; it also describes the cases when one needs to attract specialists from different fields of operation and maintenance of motor vehicles.
Digital Transformation of Executive Procedure
Authors:   All-Russian State University of Justice, Kirsanova E.V.
Published: October 2022

The article considers transformation of executive procedure in the conditions of digital economy. The author uncovers the role of development of the digital technologies and their influence on running the state. Digital state governance will allow accomplishing the final transition to digital interaction of citizens and enterprises with the state. The author also underlines that this interaction can be more comfortable for both parties. Transformation of the research subject is represented in the realization of the super service called «Digital executive procedure». Its establishment implies the launch of registry model of enforcement of court decisions. A digital registry of executive documents works as a digital state information resource that can be used for keeping the record of executive documents by the parties of executive procedures while enforcing the court decisions. The goals of establishing of this super service are: raising awareness of the parties of the executive procedure; raising transparency of work done by the bailiff who implements the executive procedure for the parties involved; simplifying the process of presenting executive documents by claimers who will execute it; simplifying the process of submitting applications, complaints, petitions to the Federal Bailiff Service of the Russian Federation. The platform for implementation of this super service can be The Unified Portal of State and Municipal Services. The operator of the registry of executive documents is supposed to be the federal Bailiff Service of the Russian Federation. The establishment of the super service is supposed to strengthen the trust of the public to the bodies of enforcement of the executive procedures and to the state in general.
Investigation of the trend and cycles using the long-term records of annual precipitation in Shandong, China
Authors: Cao Shengle , Li Xinying , You Ruifeng , Diao Yijiao , Wang Jun , Liu Yang
Published: October 2022

The length of historical records is important for analyzing trends and multidecadal variabilities in precipitation. Conventional studies usually used historical precipitation data less than 60 years, which may cause inaccurate precipitation predictions. To better understand the effects of the study period on precipitation trends and cycles, the Mann–Kendall test and Sen's slope test were applied to analyze the trend and wavelet, while the multi-temporal analysis was used to study the cycles of long historical precipitation data at four rain gauge stations in Shandong Province, China. The analysis results using long-term records show an insignificant upward trend and a longer cycle in the annual precipitation, whereas a downward trend is found when using short-term records. Furthermore, it is found that selecting the length of the representative cycle derived from the precipitation data series as the time scale for the study proved to be more reasonable. A thorough consideration of the impact of cycles on trends should, therefore, be taken to facilitate a more accurate precipitation trend analysis.
Hospital wastewater treatment and the role of membrane filtration – removal of micropollutants and pathogens: A review
Authors: Klatt Marten , Beyer Falk , Einfeldt Jörn
Published: October 2022

Dissemination of multiresistant bacteria and high concentrations of micropollutants by hospitals and other medical facilities can be significantly reduced by a wide variety of on-site treatment approaches. Membrane filtration technologies, ranging from microfiltration to reverse osmosis, have been adapted in many studies and offer multiple purposes in advanced wastewater treatment configurations. While the direct rejection of pharmaceutical compounds and pathogens can only be achieved with nanofiltration and reverse osmosis processes, porous membranes are known for their pathogen removal capabilities and can be used in combination with other advanced treatment approaches, such as oxidation and adsorption processes. This review was conducted to systematically assess studies with membrane filtration technologies that are used as either stand-alone or hybrid systems for the treatment of hospital wastewater. In this review, four different databases were screened with a pre-set of search strings to thoroughly investigate the application of membrane filtration technology in hospital wastewater treatment. Hybrid systems that combine multiple treatment technologies seem to be the most promising way of consistently removing micropollutants and pathogens from hospital wastewater, but additional economic assessments are needed for an extensive evaluation.
Contemporary application of microbubble technology in water treatment
Authors: Nair Sarita S. , Pinedo-Cuenca Ruben , Stubbs Tony , Davis Seth J. , Ganesan Poo Balan , Hamad Faik
Published: October 2022

Microbubble (MB) technology constitutes a suite of promising low-cost technologies with potential applications in various sectors. Microbubbles (MBs) are tiny gas bubbles with diameters in the micrometre range of 10–100 μm. Along with their small size, they share special characteristics like slow buoyancy, large gas–liquid interfacial area and high mass-transfer efficiency. Initially, the review examines the key dissimilarities among the different types of microbubble generators (MBG) towards economic large-scale production of MBs. The applications of MBs to explore their effectiveness at different stages of wastewater treatment extending from aeration, separation/ flotation, ozonation, disinfection and other processes are investigated. A summary of the recent advances of MBs in real and synthetic wastewater treatment, existing research gaps, and limitations in upscaling of the technology, conclusion and future recommendations is detailed. A critical analysis of the energetics and treatment cost of combined approaches of MB technology with other advanced oxidation processes (AOPs) is carried out highlighting the potential applicability of hybrid technology in large-scale wastewater treatment.
Üstbilişsel Sorgulamaya Dayalı Tasarlanan Öğrenme Ortamında Olasılık Öğrenme Süreci: Bir Öğretim Deneyi
Authors: KILIÇ Mehmet Akif , ÖZTÜRK Mesut
Published: October 2022

Bu çalışma ilköğretim matematik öğretmeni adayları için tasarlanan üstbilişsel sorgulamaya dayalı öğrenme ortamını değerlendirmek amacıyla yapılmıştır. Bu amaç doğrultusunda olasılık kavramının öğretimi için üstbilişsel sorgulamaya dayalı bir öğrenme ortamı tasarlanmıştır. Bu öğrenme ortamında her uygulamanın ardından yapılan görüşmeler ve araştırmacının izlenimleri sonucunda öğrenme ortamında düzenlemelere gidilmiştir. Yapılan düzenlemeler kapsamında matematik öğretmeni adayları için üstbilişsel sorgulamaya dayalı alternatif bir öğrenme ortamı ortaya çıkmıştır. Nitel araştırma desenine göre yürütülen bu çalışmada öğretim deneyi modeli kullanılmıştır. Çalışmaya tamamı Türk 31 matematik öğretmeni adayı katılmıştır. Çalışmanın verileri görüşme formu, gözlem formu ve katılımcı günlükleri ile toplanmıştır. Çalışmada elde edilen sonuçlar üstbilişsel sorgulamaya dayalı tasarlanan öğrenme ortamında katılımcıları çözüme götürmek üzere hazırlanan ipucu kartlarının ilk uygulamalarda gerekli olduğunu ancak ilerleyen uygulamalarda katılımcıların bu ipucu kartlarına gerek duymadığını göstermiştir. Ayrıca küçük grup çalışması olarak başlayan etkinlikler öğretmen adaylarından alınan dönütler doğrultusunda bireysel etkinliklere dönüştürülmüştür. Bireysel uygulamalarda öğretmen adaylarının küçük grup çalışmasına göre daha fazla sorgulama yaptıkları belirlenmiştir.
BİLİMİN DOĞASI ve ÖĞRETİMİ DERSİNİN ÖGRENCİLERİN BİLİMİN DOĞASINA İLİŞKİN DÜŞÜNCELERİNE ETKİSİ
Authors: SOSLU Özay
Published: October 2022

ÇÇalışmanın amacı, eğitim fakültesi genel kültür seçmeli ders programında yeralan Bilimin Doğası ve Öğretimi (BDVÖ) dersinin, öğrencilerin bilimselbilginin doğasına ilişkin düşüncelerine olan etkisini araştırmaktır. Çalışmanınörneklemini Bilimin Doğası ve Öğretimi(BDVÖ) dersini alan 44 öğrencioluşturmaktadır. Bu derste bilimin doğasına ilişkin konular öğrencilerindüşüncelerinden yola çıkılarak tartışılmıştır. Bu sürecin başlangıcında vesonunda öğrencilere “Bilimin Doğası Ölçeği”(BDÖ) uygulanmıştır. Buuygulamaların ön test ve son test verileri nicel olarak analiz edilmiştir. Analizsonuçları değerlendirildiğinde, BDVÖ dersinin öğrencilerin bilimin doğasınailişkin düşüncelerinde “Bilimde Öznellik ve Teknoloji” ve “Bilimde Teorilerinyeri” alt boyutlarında istatistiksel olarak anlamlı düzeyde gelişime yol açtığıtespit edilmiştir.
Investigation of Bioactivity Degradation During Storage of Sour Cherry
(Prunus cerasus L.) Peel Extract
Authors: Kurtulbaş Ebru , Sevgen Selcuk , Samli Ruya , Şahin Selin
Published: October 2022

Introduction:

Limited number of researches in the literature have been reported to examine
degradation stability by regression methods. Monitoring storage stability of plant extracts containing
phytochemicals has become a special field.

Objective:

This study aims to develop model equations to examine the stability of total phenolic
material (TPM) and total anthocyanin (TA) in the sour cherry peel extract under several conditions,
such as keeping the samples in a freezer (-20°C), refrigerator (4°C) and room temperature (25°C)
conditions. In addition, two types of ambient conditions (under dark and light, respectively) were
applied to observe the effect of sunlight on oxidation.

Methods:

The storage stability was monitored in terms of TPM and TA. 8 different polynomial regression
equations were produced for the data obtained under each condition in order to define the
deterioration of the TPM and TA during 60 days of the storage.

Results:

Keeping the samples in the light at ambient conditions was the least efficient for stability
(~10 days), while the shelf life of the product could have been quite long with the storage in the
freezer after opening the package of the product.

Conclusions:

The most suitable condition for both TPM and TA has been determined as -20 °C
with the calculation of degradation days as 157 and 115 (R^2 = 0.9874 / 0.9265, and average error
rates = 0.207097 % / 0.119541 %).
Superior Anticancer Potential of Nano-Paclitaxel Combined Bevacizumab
Treatment in Ovarian Cancer
Authors: Qu Na , Wang Chunyan , Meng Yiming , Gao Yuhua
Published: October 2022

Background:

Ovarian cancer is the second most common cancer to cause large death
among gynecological tumors. Paclitaxel is important to the standard treatment for epithelial ovarian
cancer. Due to its low solubility and permeability, nano-paclitaxel came into public view.

Objective:

To evaluate the effect of nano-paclitaxel in ovarian cancer.

Methods:

Considering the importance of bevacizumab in clinical treatment, we set four groups for
research: control, paclitaxel, paclitaxel + bevacizumab, and nano-paclitaxel + bevacizumab. CCK-8,
apoptosis, and cell cycle assays were used to detect the cell survival condition. qRT-PCR and western
blot were used to detect the gene mRNA and protein expression level. Tumor xenograft in nude
mice was used to detect the effect in vivo.

Results:

The nano-paclitaxel combined with bevacizumab had the best curative effect. Moreover, the
downstream indicators, such as caspases, BAX, FAS, OGFr, PD-L1 and VEGF, changed in four
groups, which suggested that the therapy worked by affecting the cell apoptosis, cell cycle, angiogenesis,
and immune reaction.

Conclusion:

In conclusion, the study helped us better commandof nano-paclitaxel for ovarian cancer
treatment and thus could play a role in OC therapy.
Hypertension Risk Prediction Based on SNPs by Machine Learning
Models
Authors: Kargari Mehrdad , Lajevardi S. Ali , Daneshpour Maryam S. , Akbarzadeh Mahdi
Published: October 2022

Background:

Hypertension is one of the most significant underlying ailments of cardiovascular disease; hence, methods that can accurately reveal the risk of hypertension at an early age are essential. Also, one of the most critical personal health objectives is to improve disease prediction accuracy by examining genetic variants.

Objective:

Therefore, various clinical and genetically based methods are used to predict the disease; however, the critical issue with these methods is the high number of input variables as genetic markers with small samples. One approach that can be used to solve this problem is machine learning.

Methods:

This study was conducted on participants' genetic markers in 20-year research of cardiometabolic genetics in Tehran (TCGS). Various machine learning methods were used, including linear regression, neural network, random forest, decision tree, and support vector machine. The top ten genetic markers were identified using importance-based ranking methods, including information gain, gain ratio, Gini index, χ², relief, and FCBF.

Results:

A model based on a neural network with AUC 89% was presented. This model has an accuracy and an f-measure of 0.89, which shows the quality. The final results indicate the success of the machine learning approach.
Cinobufotalin Induces Ferroptosis to Suppress Lung Cancer Cell Growth by lncRNA
LINC00597/hsa-miR-367-3p/TFRC Pathway via Resibufogenin
Authors: Lu Meizhen , Huang Junming , Deng Caijiu , Guo Tianshen , Chen Xiaofeng , Chen Peixi , Du Shaoshan
Published: October 2022

Background:

Lung cancer is the leading cause of cancer-associated death and the first most diagnosed cancer in the world. More than 2 million new cases are diagnosed and 1.6 million people die due to lung cancer every year. It is urgent to explore novel drugs and approaches for lung cancer treatment. Cinobufotalin is a TCM isolated from dried toad venom, which has been used to treat lung cancer, However, the precise mechanism remains not clear.

Objective:

This study was to investigate the mechanism of cinobufotalin treated in lung cancer.

Methods:

Cell growth was identified by Cell Counting Kit-8 (CCK-8) assay. Besides, ferroptosis of lung cancer cells was determining by intracellular iron content, lactate dehydrogenase (LDH) release and mitochondrial membrane potential. Moreover, RNA levels and proteins were detected by quantitative reverse transcription-PCR (qRT-PCR) and Western blot (WB), respectively. In addition, the regulatory effect of hsa-miR-367-3p on TFRC was confirmed by luciferase reporter assay.

Results:

This study indicated that cinobufotalin suppressed lung cancer cell growth through resibufogenin. Besides, cinobufotalin induced ferroptosis in lung cancer cells through resibufogenin. Moreover, cinobufotalin increased lncRNA LINC00597 level whereas downregulated hsa-miR-367-3p expression in lung cancer cells via resibufogenin. In addition, ferroptosis inducer transferrin receptor (TFRC) was the target of hsa-miR-367-3p, and lncRNA LINC00597 upregulates TFRC expression through sponging hsa-miR-367-3p in lung cancer cells.

Conclusion:

In summary, this study indicated that cinobufotalin induced ferroptosis to suppress lung cancer cell growth by lncRNA LINC00597\hsa-miR-367-3p\TFRC pathway via resibufogenin, which might provide novel therapeutic targets for lung cancer therapy.
Relation between Soluble CD14 Levels, Inflammation, Subclinical Atherosclerosis
and Mortality in Hemodialysis Patients
Authors: Abdallah Amany Mohamed , Elhakeem Heba , Yahia Mohamed Basiouny , Youssef Eman Mohy Ibrahim , El-Khouly Nashwa , Elmohaseb Ghada Fathy , Awad Eman Abu-Elnasr , Hassan Marwa Mohamed , Ghamry Esam Mohamed , Abdelhamed Mohamed Rashed , Kotb Essam , Mahmoud Tamer Mohamed
Published: October 2022

Background and Aim:

Chronic kidney disease (CKD) is characterized by persistent lowgrade
inflammation. Soluble CD14 (sCD14) is involved in many pathological conditions, including
inflammation and atherosclerosis. The present study aimed to assess the relationship between
sCD14 levels, subclinical atherosclerosis (SCA), inflammation and mortality in Egyptian hemodialysis
(HD) patients.

Patients and Methods:

The present longitudinal study included 62 HD patients. All patients were
submitted to careful history taking, thorough clinical examination and laboratory assessment for
high-sensitivity C-reactive protein (hsCRP) and sCD14. Carotid intima-media thickness (CIMT)
was also assessed. Patients were followed for a maximum of 18 months. The primary outcome is
patients’ mortality. Data were statistically analyzed using standard descriptive, comparative, correlative
and regression methods.

Results:

The present study was conducted on 62 HD patients. They comprised 34 males and 28
females with an age of 54.6 ± 9.0 years. At the end of follow-up, 12 patients (19.4 %) died. It was
shown that survivors had significantly lower hsCRP levels (104.2 ± 38.2 versus 134.1 ± 15.3 mg/dL,
p < 0.001), lower sCD14 levels (32.7 ± 10.3 versus 47.4 ± 18.4 μg/mL, p = 0.02) and lower CIMT
(1.32 ± 0.5 versus 1.5 ± 0.2 mm, p = 0.049). sCD14 levels were significantly correlated with hsCRP
(r = 0.4, p = 0.001) and CIMT (r = 0.31, p = 0.013). Multivariate analysis identified HD duration
[HR (95% CI): 1.02 (1.0-1.04), p = 0.021] and sCD14 levels [HR (95% CI): 1.06 (1.0-1.12), p =
0.026] as significant predictors of patients’ survival.

Conclusions:

sCD14 levels in this cohort of HD patients are well-correlated with hsCRP levels and
CIMT. In addition, they are significant predictors of patients’ mortality.