bluuebunny/crossref_metadata_2025 huggingface dataset:
Klaprothite, péligotite and ottohahnite, three new minerals with bidentate UO7–SO4linkages from the Blue Lizard mine, San Juan County, Utah, USA
Authors: Kampf Anthony R. , Plášil Jakub , Kasatkin Anatoly V. , Marty Joe , Čejka Jiří
Published: June 2017

The new minerals klaprothite (IMA2015-087), Na6(UO2)(SO4)4(H2O)4, péligotite (IMA2015-088), Na6(UO2)(SO4)4(H2O)4and ottohahnite (IMA2015-098),Na6(UO2)2(SO4)5(H2O)7·1.5H2O, were found in the Blue Lizard mine, San Juan County, Utah, USA, where they occur together as secondary phases. All three minerals occur as yellowish-green to greenish-yellow crystals, are brittle with irregular fracture, have Mohs hardness of ∼2½ and exhibit bright bluish-green fluorescence, and all are easily soluble in room temperature H2O. Only klaprothite exhibits cleavage; perfect on {100} and {001}. Quantitative energydispersive spectroscopy analyses yielded the empirical formulas Na6.01(U1.03O2)(S0.993O4)4(H2O)4, Na5.82(U1.02O2)(S1.003O4)4(H2O)4and Na5.88(U0.99O2)2(S1.008O4)5(H2O)8.5for klaprothite, péligotite and ottohahnite, respectively. Their Raman spectra exhibit similar features. Klaprothite is monoclinic,P21/c,a= 9.8271(4),b= 9.7452(3),c= 20.8725(15) Å, β = 98.743(7)°,V= 1975.66(17)Å3andZ= 4. Péligotite is triclinic,P1̄,a= 9.81511(18),b= 9.9575(2),c= 10.6289(8) Å, α = 88.680(6)°, β = 73.990(5)°, γ = 89.205(6)°,V= 998.22(8) Å3andZ=2. Ottohahnite is triclinic,P1̄,a= 9.97562(19),b= 11.6741(2),c= 14.2903(10) Å, α = 113.518(8)°, β = 104.282(7)°, γ = 91.400(6)°,V= 1464.59(14) Å3andZ= 2. The structures of klaprothite(R1= 2.22%) and péligotite (R1= 2.28%) both contain [(UO2)(SO4)4]6–clusters in which one SO4group has a bidentate linkage with the UO7polyhedron; Na–O polyhedra linkclusters into thick heteropolyhedral layers and link layers into frameworks; the structures differ in the configuration of Na–O polyhedra that link the layers. The structure of ottohahnite (R1= 2.65%) contains [(UO2)4(SO4)10]12–clusters in which each UO7polyhedron has a bidentate linkage with one SO4group; Na–O polyhedra link clusters into a thin heteropolyhedral slice and also link the slices into a framework. The minerals are named for Martin Heinrich Klaproth (1743–1817), Eugène-MelchiorPéligot (1811–1890) and Otto Hahn (1879–1968).
Ethnicity and long-term course and outcome of psychotic disorders in a UK sample: The ÆSOP-10 study
Authors: Morgan Craig , Fearon Paul , Lappin Julia , Heslin Margaret , Donoghue Kim , Lomas Ben , Reininghaus Ulrich , Onyejiaka Adanna , Croudace Tim , Jones Peter B. , Murray Robin M. , Doody Gillian A. , Dazzan Paola
Published: June 2017

Background

The incidence of psychotic disorders is elevated in some minority ethnic populations. However, we know little about the outcome of psychoses in these populations.

Aims

To investigate patterns and determinants of long-term course and outcome of psychoses by ethnic group following a first episode.

Method

ÆSOP-10 is a 10-year follow-up of an ethnically diverse cohort of 532 individuals with first-episode psychosis identified in the UK. Information was collected, at baseline, on clinical presentation and neurodevelopmental and social factors and, at follow-up, on course and outcome.

Results

There was evidence that, compared with White British, Black Caribbean patients experienced worse clinical, social and service use outcomes and Black African patients experienced worse social and service use outcomes. There was evidence that baseline social disadvantage contributed to these disparities.

Conclusions

These findings suggest ethnic disparities in the incidence of psychoses extend, for some groups, to worse outcomes in multiple domains.
Risk Stratification for Second Primary Lung Cancer
Authors: Han Summer S. , Rivera Gabriel A. , Tammemägi Martin C. , Plevritis Sylvia K. , Gomez Scarlett L. , Cheng Iona , Wakelee Heather A.
Published: June 2017

Purpose

This study estimated the 10-year risk of developing second primary lung cancer (SPLC) among survivors of initial primary lung cancer (IPLC) and evaluated the clinical utility of the risk prediction model for selecting eligibility criteria for screening.

Methods

SEER data were used to identify a population-based cohort of 20,032 participants diagnosed with IPLC between 1988 and 2003 and who survived ≥ 5 years after the initial diagnosis. We used a proportional subdistribution hazards model to estimate the 10-year risk of developing SPLC among survivors of lung cancer LC in the presence of competing risks. Considered predictors included age, sex, race, treatment, histology, stage, and extent of disease. We examined the risk-stratification ability of the prediction model and performed decision curve analysis to evaluate the clinical utility of the model by calculating its net benefit in varied risk thresholds for screening.

Results

Although the median 10-year risk of SPLC among survivors of LC was 8.36%, the estimated risk varied substantially (range, 0.56% to 14.3%) when stratified by age, histology, and extent of IPLC in the final prediction model. The stratification by deciles of estimated risk showed that the observed incidence of SPLC was significantly higher in the tenth-decile group (12.5%) versus the first-decile group (2.9%; P < 10−10). The decision curve analysis yielded a range of risk thresholds (1% to 11.5%) at which the clinical net benefit of the risk model was larger than those in hypothetical all-screening or no-screening scenarios.

Conclusion

The risk stratification approach in SPLC can be potentially useful for identifying survivors of LC to be screened by computed tomography. More comprehensive environmental and genetic data may help enhance the predictability and stratification ability of the risk model for SPLC.
Mobilized Peripheral Blood Stem Cells Versus Unstimulated Bone Marrow As a Graft Source for T-Cell–Replete Haploidentical Donor Transplantation Using Post-Transplant Cyclophosphamide
Authors: Bashey Asad , Zhang Mei-Jie , McCurdy Shannon R. , St. Martin Andrew , Argall Trevor , Anasetti Claudio , Ciurea Stefan O. , Fasan Omotayo , Gaballa Sameh , Hamadani Mehdi , Munshi Pashna , Al Malki Monzr M. , Nakamura Ryotaro , O’Donnell Paul V. , Perales Miguel-Angel , Raj Kavita , Romee Rizwan , Rowley Scott , Rocha Vanderson , Salit Rachel B. , Solh Melhem , Soiffer Robert J. , Fuchs Ephraim Joseph , Eapen Mary
Published: June 2017

Purpose

T-cell–replete HLA-haploidentical donor hematopoietic transplantation using post-transplant cyclophosphamide was originally described using bone marrow (BM). With increasing use of mobilized peripheral blood (PB), we compared transplant outcomes after PB and BM transplants.

Patients and Methods

A total of 681 patients with hematologic malignancy who underwent transplantation in the United States between 2009 and 2014 received BM (n = 481) or PB (n = 190) grafts. Cox regression models were built to examine differences in transplant outcomes by graft type, adjusting for patient, disease, and transplant characteristics.

Results

Hematopoietic recovery was similar after transplantation of BM and PB (28-day neutrophil recovery, 88% v 93%, P = .07; 100-day platelet recovery, 88% v 85%, P = .33). Risks of grade 2 to 4 acute (hazard ratio [HR], 0.45; P < .001) and chronic (HR, 0.35; P < .001) graft-versus-host disease were lower with transplantation of BM compared with PB. There were no significant differences in overall survival by graft type (HR, 0.99; P = .98), with rates of 54% and 57% at 2 years after transplantation of BM and PB, respectively. There were no differences in nonrelapse mortality risks (HR, 0.92; P = .74) but relapse risks were higher after transplantation of BM (HR, 1.49; P = .009). Additional exploration confirmed that the higher relapse risks after transplantation of BM were limited to patients with leukemia (HR, 1.73; P = .002) and not lymphoma (HR, 0.87; P = .64).

Conclusion

PB and BM grafts are suitable for haploidentical transplantation with the post-transplant cyclophosphamide approach but with differing patterns of treatment failure. Although, to our knowledge, this is the most comprehensive comparison, these findings must be validated in a randomized prospective comparison with adequate follow-up.
NGOs as learning organizations: Investigating the means and the potential
Authors: Vathis Panagiota
Published: June 2017

The work of NGOs, especially in the present times, faces growing competition and shrinking budgets. They have to demonstrate that they make good use of the resources, while being obliged to learn from their actions and experiences and try new methods and practices, in order to be competitive and effective. This article, explores the role of NGOs in providing incentives, means and opportunities for organizational learning. Our main aim is to present basic methods and good practices for their efficient function.
‘Benchmark for terms and conditions is long overdue’
Authors: Lawson Deborah
Published: June 2017

The crisis in early years recruitment has come at a time when the sector needs to expand capacity to meet demand for 30 hours. In this Q&A, Deborah Lawson, general secretary at Voice, addresses the challenges.
Online or face-to-face? Take ownership of training
Authors: Robinson Madeleine
Published: June 2017

National Day Nurseries is continually updating and refining the training it offers. Madeleine Robinson, its national training manager, outlines which courses are currently in demand and what these deliver.
Busy being creative
Authors: McKeown Sal
Published: June 2017

Busy Things' digital resources are about exploring, playing and having fun, rather than finding a right answer. Sal McKeown hears first hand from a nursery about how the software is boosting chidlren's confidence.
What will I be?
Authors: Williams Brenda
Published: June 2017

This month Brenda Williams' poem captures the exciting world of grown up occupations. Kit out your role-play area as a doctor's surgery or other familiar workplace and observe how children play.
Revision for prosthetic joint infection following hip arthroplasty
Authors: Lenguerrand E. , Whitehouse M. R. , Beswick A. D. , Jones S. A. , Porter M. L. , Blom* A. W.
Published: June 2017

Objectives

We used the National Joint Registry for England, Wales, Northern Ireland and the Isle of Man (NJR) to investigate the risk of revision due to prosthetic joint infection (PJI) for patients undergoing primary and revision hip arthroplasty, the changes in risk over time, and the overall burden created by PJI.

Methods

We analysed revision total hip arthroplasties (THAs) performed due to a diagnosis of PJI and the linked index procedures recorded in the NJR between 2003 and 2014. The cohort analysed consisted of 623 253 index primary hip arthroplasties, 63 222 index revision hip arthroplasties and 7585 revision THAs performed due to a diagnosis of PJI. The prevalence, cumulative incidence functions and the burden of PJI (total procedures) were calculated. Overall linear trends were investigated with log-linear regression.

Results

We demonstrated a prevalence of revision THA due to prosthetic joint infection of 0.4/100 procedures following primary and 1.6/100 procedures following revision hip arthroplasty. The prevalence of revision due to PJI in the three months following primary hip arthroplasty has risen 2.3-fold (95% confidence interval (CI) 1.3 to 4.1) between 2005 and 2013, and 3.0-fold (95% CI 1.1 to 8.5) following revision hip arthroplasty. Over 1000 procedures are performed annually as a consequence of hip PJI, an increase of 2.6-fold between 2005 and 2013.

Conclusions

Although the risk of revision due to PJI following hip arthroplasty is low, it is rising and, coupled with the established and further predicted increased incidence of both primary and revision hip arthroplasty, this represents a growing and substantial treatment burden. Cite this article: E. Lenguerrand, M. R. Whitehouse, A. D. Beswick, S. A. Jones, M. L. Porter, A. W. Blom. Revision for prosthetic joint infection following hip arthroplasty: Evidence from the National Joint Registry. Bone Joint Res 2017;6:391–398. DOI: 10.1302/2046-3758.66.BJR-2017-0003.R1.
When the people speak – and decide: deliberation and direct democracy in the citizen assembly of Glarus, Switzerland
Authors: Gerber Marlène , Mueller Sean
Published: June 2017

This article analyses deliberative direct democracy. It asks whether ordinary citizens are willing and able to deliberate and whether their participation in policy-making has the intended effect. We apply Bayesian logistic analyses to 500 speeches held between 2000 and 2012 at the Glarus citizen assembly. We find that every second government proposal is challenged through deliberation, with success to be higher if well argued for. However, politicians are both better at deliberating and more successful than ordinary citizens. Thus, citizens still need the political elite to do their bidding – or at least not to argue well when opposing them.
Caracterização hidrogeológica dos aquíferos cársticos sapucari e maruim, bacia sedimentar de sergipe-alagoas, nordeste do Brasil
Authors: Ribeiro Daniela Dantas de Menezes , Nascimento Sergio Augusto de Morais , Garcia Antonio Jorge Vasconcellos
Published: June 2017

Este artigo caracterizou os aquíferos cársticos Sapucari e Maruim, Bacia Sedimentar de Sergipe-Alagoas, nos municípios de Laranjeiras, Nossa Senhora do Socorro e Maruim, a partir da análise de parâmetros hidrodinâmicos e reservas hídricas. Os parâmetros analisados foram: a vazão (V); a capacidade específica (Sc); os níveis estático (NE) e dinâmico (ND); a transmissividade (T); os aspectos geológicos, geomorfológicos (feições cársticas) e estruturais, integrados num modelo hidrogeológico conceitual. Na área de estudo a investigação hidrogeológica se tornou necessária devido à importância dos recursos hídricos subterrâneos para o abastecimento humano e industrial. Para a determinação da transmissividade foi aplicado o método da recuperação de Theis (1935), usando a correlação T com capacidade específica (Sc). Os resultados de T são heterogêneos em ambos os aquíferos, destacando-se o Sapucari. Neste, a T média é de 725,42 m2/d, já no aquífero Maruim é de 113,42 m2/d. O volume anual de água extraída por meio de obras de captação existentes corresponde a 26,2% da reserva renovável do Sapucari e 11,6% do aquífero Maruim
Modelling the relationships among social studies learning environment, self-efficacy, and critical thinking disposition
Authors: Meral Elif , Taş Yasemin
Published: June 2017

This study aims to investigate the relationships among the features of learning environment (investigation, equity, and student cohesiveness) in social studies class, self-efficacy and critical thinking disposition (engagement, maturity and innovativeness) among middle school students. The study group consists of 422 students studying at five middle schools in one of the largest cities located in eastern part of Turkey. The research data was collected by using UF/EMI Critical Thinking Disposition Scale, "What is happening in this class?" Scale and the Motivated Strategies for Learning Questionnaire. Structural equation modelling (SEM) was performed by using LISREL 8.80 programme to test the hypothesized relationships among constructs. The results show that self-efficacy among students is higher in classroom environments where investigation is encouraged and equity among students is overseen. It is found that critical thinking disposition is higher in students with higher self-efficacy. Besides this, it is further observed that learning environment with investigation predicts all critical thinking dispositions positively whereas student cohesiveness predicts only maturity positively.
Wyznaczanie granicy zdania - człowiek vs maszyna
Authors: Lipnicki Michał
Published: June 2017

The paper aims at presenting the results of an experiment checking the possibility of an accurate reconstruction of text sentence boundary done by humans and computer programme with possible application in presenting the output of automatic speech recognition systems. The results are compare with the assesment of received sentences acceptability.
Trójwarstwowa struktura informacji w treści wypowiedzi1 (szkic o programie Gramatyki Rozproszonej)
Authors: Włodarczyk André , Włodarczyk Hélène
Published: June 2017

The idea of the three-tier information structure in the content of utterances is the result of research carried out in a transdisciplinary spirit, within sciences such as linguistics, psychology, logic and computer science. The theory of Meta-Informative Centering (MIC) of attention, which borrows the concept of attention centering from psychology and the concept of information from computer science, makes it possible to treat ―information structures" or "thematic-rhematic structures" as strictly dependent on the canonical form of utterances (as the manifestation of predication). Thus, an important feature of the MIC theory is its reference to predication, and in particular to the language of classical logic (first-order predicate logic). In the light of MIC theory, "information structure" appears in fact to be a structure of meta-information (representing "information about information") with respect to orthoinformation (proper information; i.e. situation frame, its types and aspects, roles, spatio-temporal anchors etc.) contained in the utterances. It is the theory of Associative Semantics (AS), which is being developed in parallel to the theory of MIC, which constitutes the layer of ortho-information. However, the foundational role in the structure of information content of utterances is played by para-information ("information which is similar or related to some other information"). In order to treat systematically the structure of information (ortho-, meta- and para-information) as contained in language utterances, and for representing their fundamental components, we proposed using ―formal concepts‖ belonging to the rapidly developing new field of research in computer science under the general name of ―Formal Concept Analysis‖ (FCA). The most important operations (responsible for the structure of information contained in the body of the utterances) are as follows: (a) selection (for building conceptual areas of interest in the para-information tier), (b) configuration (for building relationships between concepts in the ortho-information tier) and (c) centering (secondary selection of concepts for transmitting in the meta-information tier), while the most important operations (responsible for the structure of utterances) are: (a) nesting (for building utterances as units of discourse in the profile, across the tiers) and (b) encapsulation (for designating the conceptual space and combining conceptual representations with the language). In this paper we present one of the many areas of application of the described theoretical foundation, namely: word order in linguistic typology. Research taking into account the abovementioned three kinds of information constitutes a contribution to the construction of a coherent theoretical framework for Distributed Grammar (i.e. multi-tier grammar with a generalized idiomatics).
The Influence of Verse Form on the Relative Order of the Name and the Title King within an Appositive Phrase in Laȝamon’s Brut
Authors: Shinkawa Seiji
Published: June 2017

This article is an attempt to determine possible factors that affect the arrangement of a name and the titlekingin apposition in the transitional period from Old English to Middle English from a prosodic perspective as a first step to explain how preferred patterns have shifted from the types represented byAlfred King,the King AlfredandAlfred the Kingin Old English to almost exclusively the type represented byKing Alfredin Present-Day English. Contrary to the common and generally sensible judgment of avoiding poetic texts in a syntactic investigation such as this, the present study analyzes the two extant versions of Laȝamon’sBrut, an Early Middle English metrical chronicle, on the grounds that verse may serve a better purpose than prose when intonation and rhythm are centrally involved, as is the case with this study. Use of searchable large-scale electronic corpora may at first glance seem more suitable for research of this kind, but such studies involving multiple texts of different periods, places and types are prone to oversimplification, and crucial details may be missed or glossed over. For a more detailed and coherent account of the development of appositive constructions, this study provides an in-depth analysis of the linguistic situation in a single body of closely related texts.
Asymptotic behavior of solutions of fractional nabla q-difference equations
Authors: Jia Baoguo , Erbe Lynn , Peterson Allan
Published: June 2017

We are concerned with the
ν-th order nabla fractional q-difference equation (quantum equation)

∇

q
,

ρ
⁢

(
1
)

ν

⁡
x

⁢

(
t
)

=

c
⁢

(
t
)

⁢
x
⁢

(
t
)

,

t
∈

q

ℕ
1

\nabla^{\nu}_{{q,\rho(1)}}x(t)=c(t)x(t),t\in q^{\mathbb{N}_{1}}

, where

q
>
1

{q>1}

,

ℕ
1

=

{
1
,
2
,
…
}

{\mathbb{N}_{1}=\{1,2,\dots\}}

,

ρ
⁢

(
1
)

=

q

-
1

{\rho(1)=q^{-1}}

. We prove that for

0
<
ν
<
1

{0<\nu<1}

and

c
⁢

(
t
)

≤
0

{c(t)\leq 0}

,

t
∈

ℕ
1

{t\in\mathbb{N}_{1}}

, any solution of the q-difference equation with

x
⁢

(
1
)

>
0

{x(1)>0}

satisfies

lim

t
→
∞

⁡

x
⁢

(
t
)

=
0

\lim_{t\to\infty}x(t)=0

. This asymptotic result shows that the solutions of the nabla fractional q-difference
equation

∇

q
,

ρ
⁢

(
1
)

ν

⁡
x

⁢

(
t
)

=

c
⁢
x
⁢

(
t
)

{{\nabla^{\nu}_{{q,\rho(1)}}}x(t)=cx(t)}

,

0
<
ν
<
1

{0<\nu<1}

,

c
<
0

{c<0}

, have asymptotic behavior similar to that of the solutions of the first order nabla q-difference equation

∇
q

⁡
x

⁢

(
t
)

=

c
⁢
x
⁢

(
t
)

{\nabla_{q}x(t)=cx(t)}

,

c
<
0

{c<0}

,

t
∈

q

ℕ
1

{t\in q^{\mathbb{N}_{1}}}

.
Subclinical hypothyroidism does not influence the metabolic and hormonal profile of women with PCOS
Authors: Trakakis Eftihios , Pergialiotis Vasilios , Hatziagelaki Erifili , Panagopoulos Periklis , Salloum Ioannis , Papantoniou Nikolaos
Published: June 2017

Background

Subclinical hypothyroidism (SCH) is present in 5%–10% of polycystic ovary syndrome (PCOS) patients. To date, its impact on the metabolic and hormonal profile of those women remains controversial. The purpose of our study is to evaluate the impact of SCH on the glycemic, lipid and hormonal profile of PCOS patients.

Materials and methods

We conducted a prospective case control study of patients that attended the Department of Gynecological Endocrinology of our hospital.

Results

Overall, 280 women with PCOS were enrolled during a time period of 7 years (2009–2015). Twenty-one patients (7.5%) suffered from SCH. The anthropometric characteristics were comparable among women with PCOS and those with SCH + PCOS. The prevalence of acne, hirsutism and anovulation did not differ. Significant differences were observed in the 2-h oral glucose tolerance test (OGTT) (p = 0.003 for glucose and p = 0.046 for insulin). The QUICKI, Matsuda and homeostatic model assessment-insulin resistance (HOMA-IR) indices where, however, similar. No difference in serum lipids was observed. Slightly elevated levels of follicle stimulating hormone (FSH) and testosterone were noted. The remaining hormonal parameters remained similar among groups. Similarly, the ovarian volume and the endometrial thickness did not differ.

Conclusions

The impact of SCH on the metabolic and hormonal profile of PCOS patients seems to be negligible. Future studies are needed in the field and their conduct in a multi-institutional basis seems to be required, given the small prevalence of SCH among women with PCOS.
Celluloid Esther: The Literary Carnivalesque as Transformed through the Lens of the Cinematic Epic
Authors: McGeough Kevin M.
Published: June 2017

The reception ofEstherhas often been fraught with attempts to make the book more palatable to the audience receiving it and to interpret the book in a manner more consistent with the values of that community. This is evidence in cinematic adaptations of the book, where the story is transformed to better suit the genre expectations of the Biblical epic and the perspectives of the intended viewers. By examining two films based onEsther – Esther and the King(1960) andOne Night with the King(2006) – some of the interpretive issues surrounding the tone and content of the Biblical source become apparent. IfEstheris best understood as a carnivalesque work, as many scholars have suggested, then the expectations of this kind of work have not been met in the cinematic adaptations. Given the importance of film in contemporary Biblical reception, these new readings ofEstherare perhaps particularly influential, at least within the restricted communities who view these movies. Likewise, analysis of these changes highlights the values of the makers of these films and the audiences who consume them.
Christian Terror in Europe? The Bible in Anders Behring Breivik’s Manifesto
Authors: Strømmen Hannah
Published: June 2017

In the attempts to understand the ideology underpinning the terror attack in Norway 22nd July 2011, and the growth of far-right extremism in Europe more generally, Christianity and the uses of the Bible are a largely neglected feature. In this article, I examine the way in which the Bible is used in Anders Behring Breivik’s manifesto, arguing that this provides an important example of the role of Christianity in far-right discourse. I show that the Bible functions as a legitimating device, glossing violence as defense of a Christian Europe; as a motivational instrument, positing God as a fellow fighter; and, as an origin for Europe. The Bible is situated in a pre-modern state where its signifying powers are policed. At the same time, it is wrenched out of this solidified framework, cut up and pasted into the manifesto hypertext in order to serve as a contemporary ally to an anti-Muslim and anti-multicultural cause.
Joint association of screen time and physical activity with anthropometric measures in Iranian children and adolescents: the weight disorders survey of the CASPIAN-IV study
Authors: Djalalinia Shirin , Qorbani Mostafa , Rezaei Negar , Sheidaei Ali , Mahdavi-Gorabi Armita , Kasaeian Amir , Motlagh Mohammad Esmaeil , Asayesh Hamid , Safiri Saeid , Kelishadi Roya
Published: June 2017

Background:

This study aims to assess the joint association of screen time (ST) and physical activity (PA) with anthropometric indices among Iranian children and adolescents.

Methods:

In this national study, 23,183 school students, aged 6–18 years, were studied. By using a multi-stage cluster sampling method, they were selected from rural and urban areas of 30 provinces of Iran. ST and PA were assessed by self-administered validated questionnaires. Height, weight, hip and waist circumferences (WC) were measured according to standard protocols, and body mass index (BMI) was calculated. ST of <2 h per day was categorized as “low” and ≥2 h per day as “high”. PA levels were obtained by a 7-day recall of sports or activities that made participants sweat or make their legs feel tired, or games that made them breathe heavily. Using this questionnaire, the score of 1–1.9 was categorized as “low” and scores between 2 and 5 as “high” PA. Logistic regression analyses were used to evaluate the joint association of PA and ST categories with odds of anthropometric measures.

Results:

In both genders, those students categorized as “Low PA & High ST” had the highest levels of BMI z-scores (boys: 0.15±1.12, girls: 0.17±1.08), WC (boys: 69.93±13.89 cm, girls: 67.30±11.26 cm), and hip circumference (boys: 82.41±13.90 cm, girls: 84.05±13.7 cm), as well as the highest prevalence of overweight (boys: 15.32%, girls: 14.04%) (p<0.001 in all comparisons). In linear multivariate model, students with “High PA & High ST” had significant increased levels of z-scores for BMI, WC and hip circumference (p<0.05).

Conclusions:

The current findings underscore the importance of reducing ST along with increasing PA for prevention and control of excess weight in children and adolescents.
Calibrating the Equilibrium Condition of a New Keynesian Model with Uncertainty
Authors: Kranz Tobias
Published: June 2017

This paper presents a theoretical analysis of the simulated impact of uncertainty in a New Keynesian model. In order to incorporate uncertainty, the basic three-equation framework is modified by higher-order approximation resulting in a non-linear (dynamic) IS curve. Using impulse response analyses to examine the behavior of the model after a cost shock, I find interest rates in the version with uncertainty to be lower in contrast to the case under certainty.
Long-lasting response to oral therapy in a young male with monogenic diabetes as part of HNF1B-related disease
Authors: Carrillo Elena , Lomas Amparo , Pinés Pedro J , Lamas Cristina
Published: June 2017

Mutations in hepatocyte nuclear factor 1β gene (HNF1B) are responsible for a multisystemic syndrome where monogenic diabetes (classically known as MODY 5) and renal anomalies, mostly cysts, are the most characteristic findings. Urogenital malformations, altered liver function tests, hypomagnesemia or hyperuricemia and gout are also part of the syndrome. Diabetes in these patients usually requires early insulinization. We present the case of a young non-obese male patient with a personal history of renal multicystic dysplasia and a debut of diabetes during adolescence with simple hyperglycemia, negative pancreatic autoimmunity and detectable C-peptide levels. He also presented epididymal and seminal vesicle cysts, hypertransaminasemia, hyperuricemia and low magnesium levels. In the light of these facts we considered the possibility of a HNF1B mutation. The sequencing study of this gene confirmed a heterozygous mutation leading to a truncated and less functional protein. Genetic studies of his relatives were negative; consequently, it was classified as a de novo mutation. In particular, our patient maintained good control of his diabetes on oral antidiabetic agents for a long period of time. He eventually needed insulinization although oral therapy was continued alongside, allowing reduction of prandial insulin requirements. The real prevalence of mutations in HNF1B is probably underestimated owing to a wide phenotypical variability. As endocrinologists, we should consider this possibility in young non-obese diabetic patients with a history of chronic non-diabetic nephropathy, especially in the presence of some of the other characteristic manifestations.

Learning points:

HNF1B mutations are a rare cause of monogenic diabetes, often being a part of a multisystemic syndrome.

The combination of young-onset diabetes and genitourinary anomalies with slowly progressive nephropathy of non-diabetic origin in non-obese subjects should rise the suspicion of such occurrence. A family history may not be present.

Once diagnosis is made, treatment of diabetes with oral agents is worth trying, since the response can be sustained for a longer period than the one usually described. Oral treatment can help postpone insulinization and, once this is necessary, can help reduce the required doses.
Powerful Genetic Association Analysis for Common or Rare Variants with High-Dimensional Structured Traits
Authors: Zhan Xiang , Zhao Ni , Plantinga Anna , Thornton Timothy A , Conneely Karen N , Epstein Michael P , Wu Michael C
Published: June 2017

Genetic association studies often collect a wide range of complex traits, including high-dimensional and structured omics measurements. The complex...

Many genetic association studies collect a wide range of complex traits. As these traits may be correlated and share a common genetic mechanism, joint analysis can be statistically more powerful and biologically more meaningful. However, most existing tests for multiple traits cannot be used for high-dimensional and possibly structured traits, such as network-structured transcriptomic pathway expressions. To overcome potential limitations, in this article we propose the dual kernel-based association test (DKAT) for testing the association between multiple traits and multiple genetic variants, both common and rare. In DKAT, two individual kernels are used to describe the phenotypic and genotypic similarity, respectively, between pairwise subjects. Using kernels allows for capturing structure while accommodating dimensionality. Then, the association between traits and genetic variants is summarized by a coefficient which measures the association between two kernel matrices. Finally, DKAT evaluates the hypothesis of nonassociation with an analytical P-value calculation without any computationally expensive resampling procedures. By collapsing information in both traits and genetic variants using kernels, the proposed DKAT is shown to have a correct type-I error rate and higher power than other existing methods in both simulation studies and application to a study of genetic regulation of pathway gene expressions.
Decentering Expected Voices and Visibilities through Connective Learning in a Feminist Transnational Bridging Pilot
Authors: York-Bertram Sarah , Lovrod Marie , Krol Lisa
Published: June 2017

This paper outlines the learning opportunities that emerged when international students acquiring English for Academic Purposes joined Canadian undergraduates fluent in English for an Introduction to Women’s and Gender Studies. Critical reflections provided by students, course facilitators, and the graduate student researcher were gathered through surveys, interviews, and focus groups that examined experiences of academic internationalization in feminist and language acquisition classrooms, co-designed to engage difference as a valuable resource in community and knowledge-building. Results included development of mutual mentoring relationships across a wide range of educational and cultural backgrounds; honing of international students’ English-language skills through structured, intentional learning opportunities with others fluent in English; deepening awareness of non-western and Indigenous contexts as sites of critical knowledge production; and evidence that international and local newcomers to university campuses have much to offer one another. For everyone involved, there were opportunities to reflect critically on both subject matter and pedagogies of community building; use accessible language to build connections; interrogate knowledge claims emerging from the many contexts that instructors and students brought with them into learning conversations; and practice collaborative knowledge-building by probing the effects of local and global power systems in the learning pathways of students, instructors and institutions.
Liver transplantation from 73-year-old cadaveric donor
Authors: Kornilov M. N. , Minina M. G. , Miloserdov I. A. , Kruglov D. N. , Chaikin R. S. , Malakhov A. G. , Zubenko S. I. , Gautier S. V.
Published: June 2017

Orthotopic liver transplantation is the only way to cure chronic liver failure and certain liver tumors. Deceased donor organs are the prevailing source in most transplantation centers. However, there is an organ shortage because of the increasing number of patients in need of transplantation. Using expanded criteria deceased donors is a routine way to overcome organ shortage. The majority of transplantation centers take older donors depending on the local rules. Successful liver transplantation from 73-year-old deceased donor. Recipient suffered from liver neuroendocrine tumor without signs of extrahepatic spread. Liver function is adequate during 90-day follow-up. Liver transplantation from older deceased donors has good outcome according to world experience. Careful donor-recipient selection is the key to success. The first positive trial in our center enlightens the way for further practice.
Benign multiple sclerosis: aspects of cognition and neuroimaging
Authors: Ton Alyne Mendonça Marques , Vasconcelos Claudia Cristina Ferreira , Alvarenga Regina Maria Papais
Published: June 2017

ABSTRACT The existence of a benign multiple sclerosis (BMS) form is a controversial subject. Recent studies of these patients reveal different levels of cognitive impairment, despite the apparent preservation of motor function. The objective of this study was to review and analyze a number of publications that discuss the general aspects of this disease form, such as the definition criteria, prevalence, and clinical and neuroimaging markers. A systematic review of published data on BMS up to October 2015 was performed. Thirty-one published articles were analyzed. The estimated frequency of BMS varied between 6% and 73%. Cognitive impairment was recognized as affecting 17% to 47% of the subjects and presented significant correlation with neuroimaging, such as brain atrophy, increased lesion volume in T2 magnetic resonance assay, and regional grey matter atrophy. The current criteria overestimated the frequency of BMS and, for that reason, this highlights the importance of validating the diagnostic methods practiced.
Charcot’s irony and sarcasm
Authors: Teive Hélio A. G. , Germiniani Francisco M.B. , Munhoz Renato P.
Published: June 2017

ABSTRACT Jean-Martin Charcot is considered the father of modern neurology and was the first neurologist to hold a professorship of international stature devoted to the study of the diseases of the nervous system. His biographers paint an image of an austere presence, reserved manner, shyness, economy of gestures and an impenetrable, impassive face. However, a wry and sarcastic side of Charcot can be demonstrated in several situations, and these examples help to clarify the intricacies of his personality and work style.
PENETRATION, DEVELOPMENT, AND REPRODUCTION OF Meloidogyne enterolobii ON Psidium SPECIES AND INDUCED CELLULAR RESPONSES IN THE ROOTS
Authors: SOUSA ALAIN DENIS DE , PEDROSA ELVIRA MARIA RÉGIS , SILVA CLÁUDIA ULISSES DE CARVALHO , CASTRO JOSÉ MAURO DA CUNHA E , RIBEIRO JULIANA MARTINS
Published: June 2017

ABSTRACT Meloidogyne enterolobii has severely compromised the main guava producing regions in Brazil, thereby stimulating the development of resistant varieties for efficient management of this nematode. This study aimed to assess the penetration, development, reproduction, and induced cellular responses of M. enterolobii in roots of four species of the genus Psidium (P. guajava‘Paluma’, P. guineense, P. cattleyanum, and P. friedrichstalianum) from the Active Germplasm Bank (BAG) of the Center for Agricultural Research of the Semi-arid Tropics (Embrapa Semi-arid) located in Petrolina, PE, Brazil. Three experiments were carried out to assess the penetration, development, and reproduction of the nematode and, subsequently, histological analyses were performed. Nematode penetrated indistinctly in both resistant and susceptible species, but only in ‘Paluma’ an evolution was observed from vermiform juveniles to “sausage” and globose forms in experiment 1. In experiment 2, all species presented “sausage” forms of nematode, but only in ‘Paluma’, these forms reached adult female stages. In experiment 3, only ‘Paluma’ was susceptible to M. enterolobii, with reproduction factor above unity. Histological analyses showed that, except for P. guajava, the other Psidium species presented poorly developed feeding sites at 20 days after inoculation.
Transaxillary single-port subtotal parathyroidectomy: feasibility study in cadavers
Authors: Marsillac Alexandre Elmães de , Fiorelli Rossano Kepler Alvim , Phillips Henrique Neubarth , Novellino Pietro , Oliveira André Lacerda , Zorron Ricardo Paiva A. Scheiba
Published: June 2017

ABSTRACT Objective : to test the minimally invasive technique of single-port transaxillary subtotal parathyroidectomy in non-formalized cadavers to evaluate its viability and reproduction. Method : we performed ten subtotal parathyroidectomies through a transaxillary TriPort access in cadavers. The technique consisted of access through the axillary fossa, creating a subcutaneous tunnel to the anterior cervical region, for handling of the thyroid gland and dissection and resection of the parathyroid glands. Results : all surgeries were successful. The mean time of surgery was 65 minutes (57-79 min), with uncomplicated identification of all anatomical structures. There was no need for complementary incisions in the cervical region. Conclusion : the transaxillary single-port subtotal parathyroidectomy technique was feasible and reproducible, suggesting an alternative for minimally invasive cervical surgery.
Bacterial genus is a risk factor for major amputation in patients with diabetic foot
Authors: CARDOSO NATÁLIA ANÍCIO , CISNEIROS LÍGIA DE LOIOLA , MACHADO CARLA JORGE , CENEDEZI JULIANA MERLIN , PROCÓPIO RICARDO JAYME , NAVARRO TÚLIO PINHO
Published: June 2017

ABSTRACT Objective: to evaluate whether bacterial genus is a risk factor for major amputation in patients with diabetic foot and infected ulcer. Methods: we conducted a case-control, observational study of 189 patients with infected ulcers in diabetic feet admitted to the Vascular Surgery Service of the Risoleta Tolentino Neves Hospital, from January 2007 to December 2012. The bacteriological evaluation was performed in deep tissue cultures from the lesions and amputation was considered major when performed above the foot'smiddle tarsus. Results: the patients'mean age was 61.9±12.7 years; 122 (64.6%) were men. The cultures were positive in 86.8%, being monomicrobial in 72% of the cases. In patients with major amputation, Acinetobacter spp. (24.4%), Morganella spp. (24.4%), Proteus spp. (23.1%) and Enterococcus spp. (19.2%) were the most frequent types of bacteria. The most commonly isolated species were Acinetobacter baumannii, Morganella morganii, Pseudomonas aeruginosa and Proteus mirabilis. As predictors of major amputation, we identified the isolation of the generaAcinetobacter spp. and Klebsiella spp., serum creatinine ≥1.3mg/dl and hemoglobin <11g/dl. Conclusion: the bacterial genera Acinetobacter spp. and Klebsiella spp. identified in infected ulcers of patients with diabetic foot were associated with a higher incidence of major amputation.
NOS RASTROS DO CONCEITO DE PEDAGOGIAS CULTURAIS: INVENÇÃO, DISSEMINAÇÃO E USOS
Authors: Andrade Paula Deporte de , Costa Marisa Vorraber
Published: June 2017

RESUMO: Este artigo visa apresentar, analisar e discutir as condições vinculadas ao aparecimento, à disseminação e aos usos do conceito de pedagogias culturais no campo dos Estudos Culturais em Educação, especialmente no Brasil. Para o exame das injunções aí implicadas, são explorados sentidos do termo “invenção”, adotado nas ciências humanas e sociais. Analisam-se as contribuições de David Trend, Henry Giroux, Shirley Steinberg e Joe Kincheloe e Elizabeth Ellsworth, pesquisadores particularmente associados a formulações e desdobramentos do conceito. Tais legados são articulados com o objetivo de mostrar os fios que nos permitem vislumbrar as tramas desse processo de invenção.
O QUE FAZER NO ANO QUE VEM? ARTICULAÇÕES ENTRE JUVENTUDE, TEMPO E ESCOLA
Authors: Andrade Sandra dos Santos
Published: June 2017

RESUMO: Este artigo analisa o que dizem os jovens sobre futuro. O objetivo central é refletir sobre as possibilidades de articulação entre tempo, juventude e escolarização, com material empírico produzido em uma escola pública de Porto Alegre-RS. A metodologia de pesquisa foi a entrevista narrativa, analisada na perspectiva dos estudos culturais. Os jovens entrevistados frequentavam a oitava série, sendo a última oferecida pela escola, e se deparavam com a necessidade de pensar o que fazer no “ano que vem”. Como resultados, a escola continua se mostrando como um importante lugar para a construção de um futuro de sucesso. A escolarização como imperativo se fixa, então, na certificação, no status e nos acessos que, supostamente, viabiliza.
O Impacto das Habilidades Sociais para a Depressão em Estudantes Universitários
Authors: Bolsoni-Silva Alessandra Turini , Loureiro Sonia Regina
Published: June 2017

RESUMO A depressão é prevalente em universitários, embora se verifique escassez de estudos sobre habilidades sociais associadas à depressão. Objetivou-se comparar as habilidades sociais e as percepções de consequências nas interações de universitários com depressão (n=64) em relação a um grupo não clínico (n=64); e verificar o valor preditivo das habilidades sociais. Habilidades sociais e saúde mental foram mensuradas por instrumentos aferidos. Constatou-se diferenças significativas em comunicação, afeto, expressar sentimentos negativos, lidar com críticas e falar em público. O grupo com depressão relatou mais consequências e sentimentos negativos nas interações sociais. Na análise de regressão identificou-se que um repertório deficitário de habilidades sociais foi preditor de depressão, o que sugere a relevância de programas de prevenção e intervenção para essa população.
Metacontingências de Autocontrole Ético: Efeitos do Aumento da Magnitude de Reforço
Authors: Gomes Holga Cristina da Rocha , Tourinho Emmanuel Zagury
Published: June 2017

RESUMO Este trabalho objetivou avaliar os efeitos da progressão da magnitude da consequência individual concorrente com a consequência cultural sobre a recorrência de um entrelaçamento previamente selecionado por consequências culturais em um arranjo de metacontingências de autocontrole ético. Estudantes universitários compuseram duas microculturas de laboratório, as quais foram expostas a um delineamento ABACDC, em que, nas condições A e B, havia concorrência entre metacontingências e contingências operantes e, nas condições C e D, tal concorrência foi suspensa. Adicionalmente, houve progressão da magnitude da consequência individual para as respostas impulsivas (que beneficiam apenas o indivíduo) nas condições B e D. Os resultados indicaram seleção de práticas culturais de autocontrole ético tanto nas condições sem concorrência, quanto nas condições com concorrência.
Escala de Autoeficácia Ocupacional em Intervenções com Populações Vulneráveis
Authors: Freitas Clarissa Pinto Pizarro de , Damásio Bruno Figueiredo , Koller Silvia Helena
Published: June 2017

RESUMO Foram investigadas as evidências de validade da Escala de Autoeficácia Ocupacional em Intervenções com Populações Vulneráveis (EAO-IPV). A amostra foi composta por 549 profissionais da Rede de Proteção (88% mulheres), com idade média de 37,8 anos (DP = 10 anos). A estrutura fatorial da escala foi investigada por meio de modelagem de equações estruturais exploratória (MEEE). Os resultados indicaram a solução unifatorial da versão de 18 itens como a mais adequada. Os resultados das análises de validade concorrente e convergente estiveram no sentido esperado. Os índices de autoeficácia ocupacional para intervenções com populações em vulnerabilidade estiveram positivamente associados aos níveis de autoeficácia ocupacional, aos afetos positivos e à realização profissional, e negativamente associados aos afetos negativos, exaustão emocional e despersonalização.
Termos Mentais na Contação de Histórias e a Teoria da Mente das Crianças
Authors: Araujo Greicy Boness de , Sperb Tania Mara , Bittencourt Hélio Radke
Published: June 2017

RESUMO A literatura destaca a potencialidade das histórias para favorecer conversas sobre estados mentais, aspectos que contribuem para o desenvolvimento da teoria da mente. O objetivo deste estudo é verificar a relação entre a teoria da mente e o discurso narrativo de mães quanto ao emprego de termos mentais, no contexto da contação de histórias. A amostra foi constituída por 25 duplas de mães e crianças, de nível socioeconômico médio, tendo as crianças idades entre quatro e cinco anos. Os resultados mostraram que o emprego de cognições clarificadas pelas mães em suas narrativas apresenta relação significativa com a teoria da mente das crianças. A contação de histórias parece desempenhar um papel interessante na estimulação da conversação sobre termos mentais e, assim, no desenvolvimento sociocognitivo infantil.