bluuebunny/crossref_metadata_2025 huggingface dataset:
Pembingkaian fanpage@DPRamdhanpomanto dalam Melawan Hoax dan Penguatan Citra Wali Kota Makassar
Authors: Mattaliu Wawan , Ramli Ruslan
Published: October 2022

Media sosial bukan lagi sebagai media informasi tetapi juga sebagai media untuk menampung berbagai aktivitas seseorang maupun lembaga. Salah satunya, facebook yang memiliki jejaring luas dipakai untuk menyebarkan kreativitas para pengguna. Penelitian ini membahas fanpage sebagai media sosialisasi yang dikerjakan oleh Wali Kota Makassar. Pendekatannya memakai analisis kualitatif deskriptif melalui teknik pembingkaian model Pan dan Kosicki. Penelitian ini bertujuan untuk memaparkan pembingkaian Wali Kota Makassar terhadap penggunaan akun facebook. Hasilnya menunjukkan bahwa struktur retoris menguatkan citra positif Wali Kota Makassar dan posisinya sebagai pejabat publik paling menonjol dibanding anggota komunitas dan pribadi. Dominannya aktivitas pejabat publik dipakai untuk melawan hoaks dan menyampaikan progres aktivitas sebagai pejabat publik.
Identification of Anti-HIV/Migraine Drugs as Potential Inhibitors of SARS-Cov2 Main Protease Using in Silico Assessments
Authors:   Health Products Safety Research Center, Qazvin University of Medical Sciences, Qazvin, Iran., Shariatifar Hanifeh , Hooshmand Amir ,   Student Research Committee, Qazvin University of Medical Sciences, Qazvin, Iran., Gheibi Nematollah ,   Cellular and Molecular Research Center, Research Institute for Prevention of Non-communicable Diseases, Qazvin University of Medical Sciences, Qazvin, Iran., Farasat Alireza ,   Cellular and Molecular Research Center, Research Institute for Prevention of Non-communicable Diseases, Qazvin University of Medical Sciences, Qazvin, Iran.
Published: October 2022

Background: The acute respiratory syndrome named “COVID-19” is caused by a novel coronavirus called Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Lack of specific antiviral drugs or proper vaccination has led to the development of new therapeutic methods against this virus. Objective The Mpro 3Clpro is the main protease of the SARS-CoV-2 which plays an important role in replication and transcription of the virus. Therefore, targeting this enzyme is a valuable approach for drug development. Methods: In the present study, the structural properties of 69 anti-migraine and 212 anti-HIV drugs were first obtained from Drug Bank database. To select the appropriate drugs for the enzyme inhibition, the AutoDock Vina software was used. The molecular dynamics (MD) simulation method was applied for better recognition of the structural changes. Results: We identified Rimegepant (PubChem ID: 51049968), Dihydroergotamine (PubChem ID: 10531) and Ergotamine (PubChem ID: 8223) as potential inhibitors of Mpro 3Clpro. These complexes were equilibrated after 70 ns. Conclusion: Among these compounds, the anti-migraine drug “Rimegepant” showed the highest affinity for binding to the Mpro 3Clpro (-60.8 kJ/mol). This study provides enough evidence for further accomplishment of the identified compounds in the development of effective therapeutics methods against COVID-19.
Association of Two MMP-8 Gene Polymorphisms With Recurrent Pregnancy Loss in Iranian Women
Authors:   Research Institute for Prevention of Non-communicable Diseases, Qazvin University of Medical Sciences, Qazvin, Iran., Najafipour Reza , Rashvand Zahar ,   Research Institute for Prevention of Non-communicable Diseases, Qazvin University of Medical Sciences, Qazvin, Iran., Taherkhani Khadijeh ,   Research Institute for Prevention of Non-communicable Diseases, Qazvin University of Medical Sciences, Qazvin, Iran., Chamanara Solmaz ,   Department of Obstetrics and Gynecology, School of Medicine, Qazvin University of Medical science, Qazvin, Iran., Abotorabi Shokoh ,   Department of Obstetrics and Gynecology, School of Medicine, Qazvin University of Medical science, Qazvin, Iran., Moghbelinejad Sahar ,   Research Institute for Prevention of Non-communicable Diseases, Qazvin University of Medical Sciences, Qazvin, Iran.
Published: October 2022

Background: It has been reported that less than 5% of women experience recurrent pregnancy loss (RPL). different matrix metalloproteinases (MMPs) have proteolysis function with a main role in the stable development of the fetus. Objective: This study aims to assess the associations between two single nucleotide polymorphisms (rs2509013 C>T and rs11225395 G>A) of MMP-8 gene and RPL among 130 Iranian women with a history of RPL and 130 controls. Methods: Genotyping of the MMP-8 gene was done for the two polymorphisms by using Sanger sequencing method. Results: High frequency of AA genotype (OR: 2.5, 95%CI:1.02-4.1, P<0.01) and A allele (OR:1.95, 95% CI:0.95-3.1, P<0.001) of rs11225395 G>A polymorphism in patients compared to controls. This high frequency was also reported in the haplotypes and combined genotypes of polymorphism. Conclusion: The MMP-8 gene may be involved in RPL risk and is a potential biomarker for RPL susceptibility.
An Appraisal of 3D Printing Technology in Interior Architecture and Product Design
Authors: Nasir Osama , Iqbal Mohd. Faiz , Kamal Mohammad Arif
Published: October 2022

Printing technology evolves at a quick pace, and what was once only capable of printing two-dimensional objects is now capable of producing true three-dimensional objects. Three-dimensional printing, often known as 3D printing, allows you to create a work of art quickly, easily, and in great detail. 3D printers can create a wide range of objects, including statues, automobile components, toys, shoes, furniture, clothing, weaponry, human body parts, and more, and their printing capabilities will only improve in the future. This type of technology must be presented to students in a formal and creative manner in their creation activities in order to develop them to be creative thinkers who can use technology as a medium to fulfil their creativity. The technology of 3D printing can influence creativity, resulting in the realisation of ideas inside the design creation process without having to go through the lengthy design process. The purpose of this research paper is to see how creative products can be designed while using technology. The systematic literature review has been explored through internet and secondary data from relevant published academic literature from journals articles and research papers. The case study method is used to identify extensive information through an in-depth analysis of existing cases in Interior and product design.
Design Example of Catalyst Effect Analysis with Topological Graphing
Authors: Liu Yaqi
Published: October 2022

Urban catalyst theory is based on the excavation of the phenomenon of "mutual stimulation of elements", designing and amplifying the synergistic effect between elements, that is, the catalyst effect. In this paper, the topological analysis framework of the dotted-line relationship of physical space is introduced, and it is found that the topology of the catalyst effect has distinct characteristics. This is a minor innovation in the understanding of urban catalyst theory. A case of urban catalyst theory illustrates a full process of transforming the elements that produce the catalyst effect from "grand-centered structure" to "polycentric structure" to "distributed structure". Starting from the classic case, this paper reproduces and further shows the occurrence process of the catalyst effect from the perspective of topology, and uses more cases to show the design of different types of catalyst effects, providing new ideas and references for future design on catalyst effects for different situations.
NEW FINDINGS OF ARABIC INSCRIPTIONS OF THE XI–XVIII CC. IN THE VILLAGES OF AKHTY DISTRICT OF DAGESTAN.
Authors: Zakariyaev Zamir Sh.
Published: October 2022

The article is devoted to the analysis of some new findings of Arabic-language epigraphic monuments, found by the author in mountain Akhty district of Dagestan during field research, aimed at studying the rich epigraphic heritage of the district. The inscriptions are identified in different settlements, also in abandoned rural settlements in inaccessible mountainous terrain. All these inscriptions are introduced into scientific circulation for the first time. In terms of genre, the epigraphic monuments submitted in the article, are represented with building inscriptions, benevolent, proprietary inscriptions, epitaphs and excerpts from the Koran.  Chronologically the inscriptions cover the period from the XI c. up to the end of the XVIII c. Part of the inscriptions are dated. To determine the time of writing of undated inscriptions the dating technique by paleographic features of writing is mainly used. The earliest inscriptions are made in Arabic “kufi” handwriting. Kufic inscriptions are first found in highland lezgin villages Maza and Gdym. The findings of kufic inscriptions in the village Maza confirm the information from written sources that this village has centuries-old history. Consequently, the information about the early history of the village Maza, which is set out in the historical essay Ta’rikh Maza, should be recognized as real. The previously unknown kufic inscription of the XII–XIII cc., revealed in the ancient village Khnow, is a fine sample of medieval Arabic calligraphy. Of great interest is the epitaph of 1468-69 preserved in the sanctuary of the village Lutkun, where the date is indicated with numbers. This fact is very rare in medieval inscriptions of Dagestan. It is suggested that one of the eponyms of the sanctuary was a muslim activist of the XV c. The inscriptions of the XVIII c. from villages Yalak, Yaltsug and Khkem inform about the construction of bridges and mausoleum, and the proprietary inscriptions of the XVIII c. from villages Yalak and Khrug are made in connection with the construction of private residential buildings.
NEW ARABIC SOURCES
ON THE HISTORY OF RELATIONSHIP OF SHAMKHAL MAHDI-KHAN TARKOVSKY AND BIYBULAT TAIMIEV
Authors: Idrisov Usup M. , Khanmurzaev Ismail I.
Published: October 2022

Within the framework of the article, the authors for the first time introduce into scientific circulation the correspondence between Shamkhal Mahdi Khan Tarkovsky, his nephew Khan Muhammad-bek and Qadi Abdulkarim al-Atagi (from the village of Atagi), dedicated to the conclusion of a political alliance between Shamkhal and the authoritative Chechen foreman Biybulat Taimiev. The correspondence, reconstructed by the authors on the basis of the newly discovered five letters of its participants, shows the complexity and contradictory views of the subjects of negotiations on their goals and objectives, as well as the ambiguous position of their active participant and mediator - qadi s. Big Atagi Abdulkarim. In addition, the letters included in this correspondence reflect the historical and political views of Mahdi Khan as an integral part of his political program to restore the former power of Tarkov shamkhalism. The published letters significantly clarify the details and mechanisms of interaction between Shamkhal Mahdi Khan and Biybulat Taimiev and other influential figures in Chechnya. The analysis of the content of the letters being analyzed is based on textual, paleographic and historical-comparative methods of analysis. The article also reveals the political context of the studied correspondence.
TÜRKİYE İLE BALKAN ÜLKELERİ ARASINDA İŞGÜCÜ AKIŞKANLIĞI VE SOSYAL GÜVENLİK SÖZLEŞMELERİ
Authors: BULUT Mehmet
Published: October 2022

Uluslararası göçün en önemli sonuçlarından birisi ülkeler arası işgücü akışkanlığıdır. Uluslararası göçün niteliği ve göç edilen ülkenin iktisadi, sosyal ve kültürel yapısı, yer değiştiren işgücünün etkisini olumlu veya olumsuz yönde belirleyebilmektedir. Söz konusu işgücü akışkanlığı nedeniyle ortaya çıkması muhtemel sorunların ulusal mevzuat ile çözümlenmesi tam olarak mümkün olmayabilmektedir. Bu noktada uluslararası sözleşmeler etkin bir role sahiptir. İşgücü hareketliliği sonucunda uluslararası düzeyde çözüm bulunması ve hak kayıplarının önlenmesi gereken hususlardan birisi de sosyal güvenliktir. Türkiye ile Balkan ülkeleri arasında tarihi ve coğrafi açıdan önemli bir bağ bulunmaktadır. Dolayısıyla bu ülkeler arasındaki işgücü akışkanlığının boyutunun ortaya konulması ve imzalanmış ikili sözleşmelerin değerlendirilmesi önem arz etmektedir. Mevcut durumda Türkiye, Balkan ülkelerinden Bosna Hersek, Arnavutluk, Makedonya, Karadağ, Sırbistan, Hırvatistan, Romanya ve Macaristan ile ikili sosyal güvenlik sözleşmesi imzalamıştır. Makalemizde, ilk defa bir akademik çalışmada, Türkiye’nin Balkan ülkeleri ile olan işgücü akışkanlığı temelindeki ilişkileri ve sosyal güvence işbirlikleri değerlendirilmiştir.
THE IMPACT OF ENVIRONMENTAL PLANS ON THE INDUSTRIAL STRUCTURE AND DEVELOPMENT OF CITIES: THE CASE OF TEKİRDAĞ, TURKEY
Authors: YILMAZ Rasim
Published: October 2022

Although the unplanned and uncontrolled industrialization in Tekirdağ increased the rank of Tekirdağ from 23rd in 1973 to the 10th place in 2013 in the development ranking among the provinces in Turkey, industrialization and industrial facilities with high environmental impacts brought many environmental problems and started to pose a great threat in terms of environmental sustainability in Tekirdağ. Especially after the 2008 global financial crisis, environmental sensitivity has gained an international dimension. In a similar vein, the Ergene River Basin Environmental Management Master Plan and 1/100,000-scaled the Thrace Sub-Region Ergene Basin Environmental Plan came into force in 2009 upon the pollution in Tekirdağ, Turkey and its surrounding received governmental attention. 1/25,000 Scale Tekirdağ Provincial Environmental Plan and 1/5000 Scale Master Development Plans which were prepared and elaborated in consideration of the Thrace Sub-Region Ergene Basin Environmental Plan and 1/100000-scaled Thrace Sub-Region Ergene Basin Environmental Plan affect the nature and structure of the industry in Tekirdağ and the district-based development of Tekirdağ's districts. After examining the effects of environmental plans on the structure and development of the industry in Tekirdağ, this study analyzes the impact of environmental plans on court decisions about the attempts to set up new industrial areas in Tekirdağ.
BOSNA-HERSEK’İN FOÇA KAZASI’NDAKİ SULTAN II. BÂYEZİD CAMİİ
Authors: GÜLER Dr. Nazenin Saadet
Published: October 2022

Osmanlı Devleti, hüküm sürdüğü coğrafyalarda o bölgenin imar, inşa ve gelişimi için dinî, eğitsel, kültürel ve sosyal alanlarda birçok vakıf eser kurmuştur. Bunlardan günümüze ulaşanlar kuruldukları bölgelerde Osmanlı medeniyeti ve dönemin yönetim anlayışının izlerini taşıyan önemli eserlerdir. Bu eserlerden biri de II. Bâyezid’ın Foça’da inşa ettirdiği camidir. Bosna-Hersek’e bağlı bir şehir olan Foça 1465 yılında Osmanlı hâkimiyetine girmişti. İstanbul’u Dubrovnik’e bağlayan ticarî yol üzerinde bulunan Foça, tarıma elverişli bir iklime sahip olması yönüyle hem ticari hem de idari bakımdan önemli bir merkezdi. Bu stratejik konumuyla Osmanlı’nın önemli bir kenti olan Foça’da II. Bâyezid 1500 yılında bir cami inşa ettirmişti. Bosna’nın doğusunda bulunan cami 1992 yılında yıkılmış ancak daha sonra Türk İşbirliği ve Koordinasyon Ajansı Başkanlığı (TİKA) tarafından yeniden inşa ettirilmiştir. Osmanlı’nın bölgede inşa ettirdiği en eski vakıf eserleri arasında yer alan cami bu çalışmanın konusunu teşkil etmektedir. Çalışmada arşiv verileri ışığında caminin önemi ve fonksiyonel özellikleri incelenecektir.
The Solid-Liquid Mass Transfer Analysis for Delignification Process of Coffee Husk in Stirred Reactor
Authors: A Nandini  , L Edahwati  , S D Nurherdiana
Published: October 2022

The delignification process using the organosolv method is a process of removing lignin content by using organic solvents (such as ethanol). In this study, mass transfer analysis was used to determine the mass transfer coefficient of the delignification process of coffee husk. The first process was incubation process by using white rot fungi (Phanerochaete chrysosporium )in the coffee husk biomass, then followed by hydrolyzed process by using citric acid as a organosolv solvent. The delignification process were carried out under a conditions of temperature 50°C, solvent or etanol concentration 25%, speed range (500-700 rpm) and stirring time (1-4 hours with the gradient of 0,5 hours). The mass transfer effect was determined for different speed range and stirring time. From this research, the result of the mass transfer coefficient has range of 0.064/s – 0.46/s. The increasing of stirring time will affect to the mass transfer coefficient, which is also increasingly depend on the stirring time.
Strength Analysis of Frame Structure Loading in Planning Using Solidworks Static Simulation Study
Authors: R M Bisono  , N Hafidhoh  , A T A Salim
Published: October 2022

The main focus of this research is to design the frame of the various chips chopper machine that is sturdy according to the needs and has a long life. The design and simulation were carried out using the Solidworks 2020 software. The material used to make the frame structure was ASTM A36 Steel with a density of 7850 kg/m3. The mass of the chopper machine frame that has been made is 6,383 kg. By giving two kinds of loading F1 and F2 of 18.718 N and 29.4 N, the resultant displacement for F1 and F2 is 0.1088 mm and 0.0124 mm, respectively, and the maximum Von Mises Stress value is 9.846 x 106 N/m2 and 1.330 x 106 N/m2, respectively. Based on these results, according to the theoretical calculation of maximum shear stress, the maximum Von Mises stress value caused by external forces for both is very much smaller than the Yield Strength Material value (2,500 x 108 ). So that this frame structure is declared safe and can be continued into the manufacturing process of various chips chopping machines according to the workload.
Manufacturing Acetabular Liner UHMWPE using CNC Milling
Authors: W D Lestari  , L Edahwati  , R D Issafira  , W Saputro  , A K Faizin  , N Adyono  , T P Sari
Published: October 2022

Ultra High Molecular Weight Polyethylene (UHMWPE) is a biomedical polymer that is useful in the orthopedic field as a bearing component in artificial hip joints. In general, these polymers pair up and rub against each other with metallic biomaterials, namely 316L stainless steel, cobalt chromium (CoCr) and titanium, which can cause material wear problems. One way to increase the wear resistance of UHMWPE is through the manufacturing process. The purpose of this research is to manufacture acetabular liner products using a CNC milling machine to obtain high surface quality and dimensional accuracy. The CNC milling machine used is the type of YCM 1020 EV 20. The manufactured specimen is then measured for roughness and dimensional accuracy. Based on the measurement results, it is found that the acetabular liner specimens from the CNC milling process are still in accordance with the standard ASTM standard (F 2033-12).
Mini Factory Laboratory From Technology Reverse Engineering Ballet Reactors in Struvite Formation
Authors: L Edahwati  , S Sutiyono  , W D Lestari  , R  D Issafira  , W Saputro  , A K Faizin  , N Adyono  , T P Sari
Published: October 2022

Reverse Engineering (RE) can be interpreted as procedures and processes in dismantling an object to find out the materials, working methods, or technology used so that the object can function properly. Design activities using the reverse engineering concept make it easier for students to understand product specifications, product advantages and disadvantages, product production processes and production cost estimates before designing new products. The laboratory is one place that can be used to carry out the reverse engineering process. The bulkhead reactor is an alternative to the stirred tank reactor with the aim that the resulting product is maximized both in terms of quantity and morphology or shape of the material. The benefit of disassembling this product is as a first step in understanding the concept of reverse engineering in the task of designing machines or tools. From the results of the study, it was found that the formation of struvite occurred at pH 9 using an air flow rate of 1 l/minute.
Cost Estimation of Distillation Unit at Dimethyl Ether Plant Based on Production Capacity
Authors: Saputro E , Sanjoyo B A , Ramadhanti W
Published: October 2022

The aim of this research is to determine the impact of production capacity in determining distillation cost estimation on the dimethyl ether plant design. The estimation of equipment costs are determined using the CEPCI cost index. The calculation of the equipment specification was done with 4 different production capacities. The number of column height and diameter will increase when the production capacity is increased. The increase in equipment cost is directly proportional to the increase in production capacity. The greater the production capacity, the larger the height column and diameter, so the equipment cost will increase also. The equipment cost is affected by production capacity. Based on this analysis, the cost in the year 2024 will follow the model of y = 9923.8x + 2E+08, in which x is the capacity.
Analysis of Air Flow Rate in Bulkhead Reactors on Struvite Mineral
Authors: Edahwati L , Sutiyono S , Suprihatin
Published: October 2022

Struvite is a white crystalline chemical known as magnesium ammonium phosphorus hexahydrate (MgNH4PO4.6H2O). Struvite is soluble in acidic conditions and slightly soluble in neutral and alkaline conditions. In industry, struvite is known as scale in pipes. Urinary stones can be called struvite because struvite crystals can form easily in the urine of animals and humans infected with ammonia organisms produced in the urine. Struvite can potentially be formed by alkaline urine and high magnesium excretion due to a high magnesium plant- based diet. The formation of struvite minerals is carried out in an insulated reactor by mixing a solution of MgCl2, NH4OH, and H3PO4 in a ratio of 1:1:1. The treatment of struvite mineral formation was carried out with a feed inlet rate of 35 ml/minute, the temperature at the reactor was carried out at 30oC while the intake air rate was carried out in the range of 0.25-1.25 liters/min. The pH of the solution was kept at a value of 9. The process was carried out until a steady state was reached.  The formation of struvite minerals using an insulated column reactor was obtained at conditions of pH 9, operating temperature of 30oC and air rate of 1.25L/min.
PERUBAHAN PERILAKU DENGAN OPERANT CONDITIONING DAN CLASSICAL CONDITIONING PADA PENDIDIKAN DAN PELATIHAN TOEFL ONLINE MAHASISWA UPN “VETERAN” JAWA TIMUR
Authors: Swasti Ika Korika , Badi'ah Roudlotul , Anugrahadi Yoga Dwi , Odelia Evi Maya
Published: October 2022

Pembelajaran online merupakan strategi yang efektif dalam mempengaruhi hasil belajar. Pelaksanaan pelatihan online dapat menampung banyak peserta, sehingga lebih efisien tetapi kurang efektif di dalam pengontrolan keaktifan dan keseriusan dalam pembelajaran. Sehingga penelitian ini memiliki tujuan untuk mengetahui perubahan perilaku peserta pelatihan TOEFL online setelah diberikan tindakan pada proses pembelajaran dan memberikan masukan UPT Pusat Bahasa UPN “Veteran” Jawa Timur tentang strategi yang efektif untuk pembelajaran TOEFL yang dilaksanakan secara online. Penelitian ini menggunakan penelitian tindakan dengan mengujicobakan teori perilaku classical conditioning pavlov dan reinforcement skinner dalam diklat online. Hasil penelitian menunjukkan bahwa pemberian contoh perilaku dan peringatan yang dilakukan secara berulang-ulang oleh narasumber dan peneliti, membawa perubahan perilaku yang diinginkan pada peserta pelatihan. Pembiasaan dan penguatan perilaku yang diinginkan, metode dan media yang variatif, serta game interaktif dapat diterapkan UPT Pusat Bahasa UPN “Veteran” Jawa Timur sebagai strategi pembelajaran TOEFL secara online yang efektif dan efisien.
TAX GOES TO MARKET (Kegiatan Pengabdian Kepada Masyarakat oleh “Laskar BANG Kojib”)
Authors: Purbolakseto Hengky Veru
Published: October 2022

Dalam upaya untuk mendorong pemenuhan kewajiban perpajakan secara sukarela (voluntary tax compliance) serta mendorong kontribusi penerimaan negara, maka diperlukanlah kelompok independen yang dapat memberikan sosialisasi dan pendapingan terhadap masyarakat dalam pemenuhan kewajibannya di bidang perpajakan. Kelompok independen ini bisa diwakili oleh mahasiswa Kuliah Kerja Nyata dengan bertemakan “Laskar BANG Kojib” (Laskar Bersinerginya Anak Negeri Gelorakan Konstribusi Wajib). Hasil penjaringan Wajib Pajak potensial  didaerah kecamatan Sungailiat oleh Laskar BANG Kojib sampai dengan kegiatan selesai adalah sejumlah 592 WP yang terdiri dari 411 pegawai dan 181 pengusaha, jumlah ini merupakan 78% dari 760 NPWP baru yang ditargetkan.
Szerzeményezés és fenntarthatóság?
Authors: Tünde Székelyné Török
Published: October 2022

Az írás arra keres választ, hogy a könyvtáros szakma szűkebb területein, például a szerzeményezés, a feldolgozómunka vonatkozásában melyek azok a tevékenységek, amelyek a fenntarthatóság céljait szolgálhatják. A kiválasztottmunkafolyamatokon belül a lehetséges megvalósítást az ELTE Egyetemi Könyvtár és Levéltár gyakorlatábólvett példákon keresztül szemlélteti a Magyar Könyvtárosok Egyesülete 2022 júliusában Kaposváron rendezettVándorgyűlésén, a Bibliográfiai Szekcióban elhangzott előadás bővített, szerkesztett változata.
APPLICATION OF BIOIMPEDANCE ANALYSIS IN CLINICAL PRACTICE: LITERATURE REVIEW
Authors:   A.I. Burnasyan Federal Medical Biophysical Center, Moscow, Russia, Samoilov A.S. , Rylova N.V. ,   A.I. Burnasyan Federal Medical Biophysical Center, Moscow, Russia, Velichko M.N. ,   A.I. Burnasyan Federal Medical Biophysical Center, Moscow, Russia, Bodrov A.V. ,   A.I. Burnasyan Federal Medical Biophysical Center, Moscow, Russia, Sturmin A.V. ,   A.I. Burnasyan Federal Medical Biophysical Center, Moscow, Russia
Published: October 2022

The purpose of this literature review was to conduct a meta-analysis on the application of the bioimpedance measurement method in clinical practice. MEDLINE, Embase, Scopus, Web of Science, and eLibrary resources were used to search for materials from 2010 to 2021. The terms of inclusion in the search criteria were “bioimpedance analysis”, “hydration”, “body composition”, “bioimpedance measurement”. As a result of the search, 833 articles were found. Studies show that the observation of a deviation from the norm of such an indicator as the amount of water in the body (total, extracellular and intracellular) is considered one of the key factors that is used in bioimpedance measurement in clinical practice. Abnormal shifts in the body fluid are the most important indicators that can be used to assess the health of the human body.
Comparison of Long-term Outcome between Diabetic and Non-Diabetic Patients with Ischemic Heart Disease following Percutaneous Coronary Intervention: A Prospective Study
Authors: Akanda Md Abdul Kader , Reza Abeeda Tasnim , Akanda Md Muhtasim , Kabir Md Khyrul
Published: October 2022

Background: Diabetes Mellitus (DM) is an established independent predictor of adverse prognosis in patients undergoing percutaneous coronary intervention (PCI) even with improvements in diabetes treatment and interventional techniques. The aim of this study was to compare long term post PCI outcome between diabetic and non-diabetic patients with ischemic heart disease (IHD).
Method: The data was derived from a prospective observational study to evaluate the outcome after PCI in DM patients for 2 years. A total of 305 patients with IHD & DM were randomly selected and enrolled who underwent PCI from 2010 to 2013 in an urban cardiac hospital of Bangladesh. The study population were divided into two groups with group 1 consisting of patients with DM (n=108) and group 2 of patients without DM (n=197). After the PCI, all patients were followed up for 2 years. The incidences of bleeding, stent thrombosis, myocardial infarction (MI), stroke and repeat revascularization were compared.
Results: Diabetic patients had significant adverse outcomes having MI, stroke & MACCE respectively following 1 year (p= 0.018, 0.036 & 0.017) and MI following 2 years (p= 0.013) compared to non-diabetic patients. However, in multivariate analysis, diabetes mellitus was not found to be an independent predictor for 1-year & 2-year adverse events following PCI [OR 1.016 (0.317-3.259) & p 0.979, after 1 year and 1.554 (0.087 – 27.902) & p 0.765, after 2 years].
Conclusions: The outcome of PCI after 1 year and 2 years among diabetic and non-diabetic subjects with IHD differed significantly in respect of MI, stroke & MACCE. But this study failed to identify diabetes mellitus as an independent risk factor for 1-year and 2-year adverse outcomes.
Cardiovasc j 2022; 15(1): 5-12
Evaluation of the Glycosylated Haemoglobin as a Predictor of Severity of Coronary Artery Disease in Non-diabetic NSTEMI Patients
Authors: Mostofa Md Gulam , Akanda Abdul Kader , Ullah Mohammad , Rahman Md Zillur , Islam Mohammad Mamoon , Alam Md Shariful , Haque Md Ahsanul , Basak Suchitra
Published: October 2022

Background: Glycated hemoglobin (HbA1c) values reflect two to three months average endogenous exposure haemoglobin to glucose including postprandial spikes and have low intra-individual variability particularly in non-diabetic patients. Elevated HbA1c is regarded as an independent risk factor for coronary artery disease (CAD) in patients with or without diabetes mellitus (DM). The purpose of this study is to determine the correlation between the level of HbA1c and the severity of coronary artery disease in non-diabetic non ST elevation myocardial infarction (NSTEMI) patients.
Methods: This observational study was carried out with total of 64 non-diabetic patients with a history of NSTEMI. Patients were divided into 2 groups based on HbA1c - one group having HbA1c ³5.7 – 6.4% (High risk group) and another group with HbA1c < 5.7% (Low risk group). Severity of CAD was assessed using Gensini score derived from coronary angiographic data. Gensini score < 36 points was regarded as mild coronary artery disease and Gensini score 36 points as moderate to severe coronary artery disease. Then patients with high and low risk HbA1C groups were correlated with severity of CAD.
Results: Over 55.5% patients with HbA1c in high-risk group (5.7 – 6.4%) had severe CAD as opposed to 28.6% patients with HbA1c in low-Risk group (<5.7%). The individuals with high-risk group of HbA1c was 3.1 (95% of CI = 1.1 – 8.9) times more likely to have severe CAD than those with HbA1c < 5.7% (p = 0.031). Spearman correlation between HbA1c and Gensini score depicted that the two variables exhibit a linear relationship indicating that Gensini score rises parallel with the rise of HbA1c (r = 0.289, p = 0.021).
Conclusion: The study concluded that over half of the non-diabetic, NSTEMI patients with high-risk range HbA1c are likely to have severe CAD than those with HBA1c within normal range.
Cardiovasc j 2022; 15(1): 26-35
Replantation of an Amputated Hand- A Landmark surgery with Multidisciplinary Team Approach
Authors: Islam ASM Shariful , Shahidullah AYM , Mostofa Md Golam , Hossain Md Daud
Published: October 2022

An amputation of the hand is a disastrous traumatic injury especially for advanced machinery workers which adversely affects the victim’s ability to earn a livelihood, support a family, and carry out daily activities. It also produces great psychological impact. In the following case report, we described a middleaged male with an amputation at the level of the distal forearm who underwent replantation. The transfer of the amputated hand, operative technique and postoperative status are described. Awareness of the possibility of salvage should be spread among healthcare providers and the need for immediate attention by a multispecialty team is advocated. This report reviews the literature related to the operative technique, contraindications and long-term results.
Cardiovasc j 2022; 15(1): 106-110
Role of Maternal & Fetal Factors in Relation to Low Birth Weight
Authors: Islam Tasnuva , Mahboob Abdullah Al , Ahammad Forrukh
Published: October 2022

Introduction: Low birth weight (LBW) continues to remain a major public health problem worldwide. There are numerous factors contributing to LBW both maternal and fetal. The mortality of low birth weight can be reduced if the risk factors are detected early and managed by simple techniques.
Objective: To identify the maternal and fetal factors associated with low birth weight.
Materials and Methods: This case control study was conducted in Department of Pediatrics, Khulna Medical College& Hospital from January 2019 to June 2019. After delivery of the baby weight of the newborn was measured with digital weighing scale. Mothers of babies with birth weight <2500 gm were enrolled as cases and mothers of babies with birth weight _2500 gm were enrolled as controls.
Results: Total 96 mothers were enrolled in this study and 48 mothers in each group. All the information was recorded in a pretested questionnaire. Statistical analysis was done by SPSS. Primipara mother had 3.153 times more likely to deliver LBW baby. Patients having anemia had 3.316 times more likely to deliver LBW baby. Patients having hypertension had 4.120 times more likely to deliver LBW baby. Preterm delivery had 28.927 times more likely to deliver LBW baby. Primipara, anemia, hypertension and preterm delivery were significantly associated with LBW. In multivariate analysis, preterm had 20.619 times more likely to deliver LBW.
Conclusion: Primipara, anemia, hypertension and preterm delivery were significantly associated with LBW.
Medicine Today 2022 Vol.34(2): 106-110
Comparison of Lipid Profile in Different Types of Steroid Sensitive Idiopathic Relapsing Nephrotic Syndrome in Children during Active Disease and Remission
Authors: Hoque SM Shamsul , Islam Md Ashraful , Akter Taslima , Roy Ranjit Ranjan , Rahman Md Habibur
Published: October 2022

Introduction: Nephrotic syndrome is a disease of relapse and remission. Relapse rate is more than 80%. Hyperlipidemia and hypoalbuminemia are important characteristic of nephrotic syndrome. Hyperlipidemia persist even after remission of disease in frequent relapse nephrotic syndrome possibly due to frequent attack of disease and frequent use of steroid. Hyperlipidemia causes premature atherosclerosis, progressive renal injury leading to chronic renal failure, cardiac complications (myocardial infarction, hypertension), cerebrovascular disease and frequent relapse of nephrotic syndrome.
Objectives: The aim of study was to see the lipid profile and comparison of lipid profile among different types of steroid sensitive idiopathic relapsing nephrotic syndrome during active disease and in remission.
Materials and Methods: A cross sectional study included 120 ( 40 in each group) children aged 2-16 years with steroid sensitive idiopathic relapsing nephrotic syndrome patients who were admitted or attended in out patients department (OPD) in paediatric nephrology department Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh, during December 2014 to December 2015. They were clinically examined and fasting lipid profile was done in each case during active disease and after one month of urinary remission. The study population were divided into three groups- Infrequent relapse nephrotic syndrome (IFRNS), frequent relapse nephrotic syndrome ( FRNS ) and steroid dependent nephrotic syndrome (SDNS) based on clinical response.
Results: Total patients were 120 (40 in each group). The study showed a male predominance with a male to female ratio 2.24:1, male patients were 69%, female 31%. In all cases, there were increased mean total cholesterol, low density lipoprotein ( LDL ) , triglyceride (TG) and high density lipoprotein (HDL) was normal during active disease, more raised in FRNS and SDNS.There was significant decrease in the mean level of total cholesterol, LDL and triglyceride during remission ( p <0.001). Cholesterol became normal but triglyceride and LDL remained elevated even after one month of urinary remission in FRNS and SDNS.
Conclusion: Hyperlipidemia persist during remission of steroid sensitive relapsing nephrotic syndrome. Children with FRNS and SDNS should be addressed with lipid lowering medication, healthy foods and healthy life style. Multicenter prospective studies with larger sample are needed for validating the findings of the present study.
Medicine Today 2022 Vol.34(2): 111-116
Impact of Platelet Count on Non-ST Elevation Myocardial Infarction: In-Hospital Outcome
Authors: Rahman Md Zahidur , Saha Sudipto , Hassan Khan Md Ikhtiar , Chakrovortty Swadesh Kumkar , Al Mamun SK Abdullah
Published: October 2022

Introduction: Incidence of ACS is increasing in developing countries like Bangladesh. Many factors can influence in hospital outcome of NSTEMI Patient. Platelet count is one of them. The aim of present study was by measuring platelet count to detect the severity of NSTEMI patients and their in hospital outcome.
Objective: The aim of present study was to observe the impact of platelet counts on in hospital outcome of NSTEMI.
Materials and Methods: The study was conducted in Shahid Sheikh Abu Naser Specialized Hospital, Khulna from January 2021 to November-2021. NSTEMI Patient Presented within 24 hours of chest pain was included in this study. Data were collected by direct interview from Patient and venous blood was drawn for platelet count. Continuous data were expressed as mean ±SD. Categorical data were analyzed with x2 test. Student’s ‘t’ test was used for analysis of Continuous variables. Comparision between groups was done by unpaired t-test. Multiple logistic regression analysis was done to determine the association between lower platelet counts and adverse hospital events in NSTEMI patients. P-values <0.05 were be considered statistically significant.
Results: 100 Patients are included in this study. They are devided into two groups. Group-1 having platelet count <200000/cmm) and Group-II having platelet count > 200000/cmm. Bleeding, Q-wave MI, arrythmia and heart failure were significantly (P<0.05) higher in group-I but stroke and death were similar in both groups.
Conclusion: Lower platelet count in NSTEMI patient is associated with adverse in-hospital outcome.
Medicine Today 2022 Vol.34(2): 125-129
Comparative Study of Radiation Exposure of Patients undergoing Transradial and Transfemoral Coronary Angiogram and Percutaneous Coronary Intervention
Authors: Mazumder Forhad Karim , Mahmood Khaled , Md Jafar Abul Hasnat , Hoq Enamul , Sharmin Rubaba
Published: October 2022

Introduction: Coronary artery disease (CAD) is now the leading cause of death worldwide. Percutaneous coronary interventions (PCIs) are an important group of technologies for the diagnosis and treatment of patients with CAD. PCI is usually performed using the transfemoral (TF) approach but the transradial (TR) approach has been increasingly used as an alternative to TF approach due to less vascular complications, earlier ambulation and improved patient comfort. Accurate assessment of radiation exposure during PCI is paramount important as radiation has many short and long term hazards. TR and TF route has distinct advantages and disadvantages. But in respect of radiation exposure of patients there are controversial evidence between TR and TF approach.
Objective: To compare the radiation Exposure in patients with percutaneous coronary intervention by TR and TF approach.
Materials and Methods: This prospective observational comparative study was conducted in the National Institute of Cardiovascular Diseases, Dhaka, from June 2015 to May 2016. A total of 200 patients were selected and categorized into two groups (Group I= Trans radial, n =100) and (Group II = Trans femoral, n= 100). Again divided into subgroups (group Ia, trans radial CAG = 70, group IIa, trans radial PCI =30) and (group IIa, trans femoral CAG =70, group IIb, trans femoral PCI = 30). Then different outcome variables were evaluated and compared.
Results: Patient demographics were the same in both groups. Fluoroscopy time during TR and TFCAG and PCI was (4.4.±1.6 min vs 4.1±3.9 min, p=0.61) and (11.7±1.3 min vs 11.1±1.5 min, p=0.13) respectively. Regarding radiation dose during TR and TF coronary angiogram, Dose area product(DAP) were (2732±1195.5 mGym2vs 2434±488.0 mGym2, p=0.07&) and Air Kerma (AK) were (307.6 ±112.2 mGy vs 283.7±48.5 mGy, p=.10) with statistically no significant difference of radiation dose (DAP and AK) between two groups. Utilization of Contrast volume during TR and TF angiogram (64.8±8.9 vs 68.2±7.5, p=0.01) were less in trans radial group. Also Utilization of Contrast volume in TR-PCI and TF- PCI (168.0±13.0 vs 177.7±19.9 ml ,p=0.03) were less in trans radial PCI.
Conclusion: The basis of the results, no significant differences were found in patient of radiation dose in both TR and TF group. Furthermore utilization of contrast volume was lower in trans-radial CAG and PCI. Trans radial CAG and PCI can be performed with the same safety as for the trans femoral approach.
Medicine Today 2022 Vol.34(2): 130-135
Spectrum of Upper Gastrointestinal Endoscopic Findings in Patients with Dysphagia: A Study of 147 Cases
Authors: Lamichhane Ramesh , Saha Madhusudan , Yadav Gopal Kumar
Published: October 2022

Introduction: This retrospective descriptive cross-sectional study was done to see upper gastrointestinal endoscopic findings in patients presenting with dysphagia.
Materials and Methods: Reports of patients undergoing upper gastrointestinal endoscopy were retrieved from endoscopy records. Data regarding age, gender, and endoscopic features and impressions were collected. The data analysis was done using IBM SPSS® v21 (IBM, Armonk, New York). Frequency, proportions, mean ± SD, and range were calculated.
Results: Out of 147 participants, the mean age of the participants was 53.46 ± 15.99 years. There was an equal proportion of participants of each gender (50.3% female and 49.6% male). The prevalence of endoscopic abnormalities was 93.8%. Most of the participants had carcinoma esophagus (38.7%, 57) followed by gastritis (35.3%, 52), gastric polyp (10.8%, 16), and duodenitis (8.8%, 13).
Conclusion: Dysphagia is an alarming symptom that warrants prompt evaluation. With diagnostic and therapeutic value, upper GI (gastrointestinal) endoscopy remains a rapid initial effective tool in the evaluation of patients with dysphagia.
Medicine Today 2022 Vol.34(2): 136-139
Management of Uncommon Presentation of Choronic Osteomyelities of Humerus Using Ilizarov Technique in a 2 Years Old Child: A Case Report
Authors: Rob Chowdhury Foyzur , Mustofa Md Gulam , Shahnewaj SM , Bhuiyan Md Akhlas , Ahmed Tanvir , Ahmed Sahel , Rahman Habibur
Published: October 2022

Introduction: Chronic osteomyelitis is a surgical disease that can require significant dedication from both patient and surgeon to eradicate. Treatment requires isolation of pathogen, significant debridement for removal of all infective and necrotic material, then bony and soft tissue reconstruction.
Objective: We shall try to highlight the option of management of a pan-Diaphyseal osteomyelitis of a children in the new era of osteosynthesis by Ilizarov.
Discussion: A two years old baby presented to us with the H/O chronic discharging sinus and arm sling for around 3 months. After clinical history taking and examination, radiography and pus testing (C/S) and sequestrum and pathological fracture was the identifying points we took the plan for exploration curettage and drainage. Finally we fix the arm by Ilizarov osteosynthesis for more than 3 months. The wound healed and osteomyelitis resolved.
Conclusion: Use of Ilizarov osteosynthesis for fixation and wire tension effect to resolve the infection1,2
Medicine Today 2022 Vol.34(2): 157-158
SEPATU COMPASS : PRODUK LOKAL RASA DUNIA
Authors: Ma’rifatul Ulya  , Mirza Dwinanda Ilmawan Mirza , Aditya Narendra Wardhana  , Lanal Abrori Himawan
Published: October 2022

The purpose of this study was to determine consumer behavior based on factors that influence consumers to make decisions in purchasing Compass Shoes. Data collection techniques through observation, interviews, and documentation. This study used a sample of informants in Gresik who met the criteria, namely having Compass shoes and getting them through their own efforts. The theoretical basis used in this research is the Consumer Decision Making Behavior Model and the Influencing Factors ranging from environmental factors, individual differences, psychological processes to decision making processes. The results of this study indicate that consumers of Compass shoes are willing to queue to fulfill their desires and have products that are experiencing an increase in value.
Pengaruh Kualitas Pelayanan, Membership, Dan Harga Terhadap Keputusan Pembeli Pada Vape Move Ngawi
Authors: Alwani Affan Nailul Fajar , Rahaju Endang Edi , Warnaningtyas Hartirini
Published: October 2022

This study aims to examine and determine the effect of partially or simultaneously service quality, membership, and price on buyer decisions on Vape Move Ngawi. This research is an explanatory research using a quantitative approach. The samples taken in this study were 100 consumers as regular customers who bought products on Vape Move Ngawi. This research uses purposive sampling method. That is the sampling technique by setting special characteristics or special conditions with the aim of being able to answer the research statement. The data collection method used is a questionnaire distributed to 100 consumers as regular customers. The data analysis technique used classical assumption test, multiple linear regression analysis, coefficient of determination analysis, and hypothesis testing using t test and F test with the help of IBM SPSS Statistics 25 program. The results showed that (1) service quality, membership, and price were overall partial significant effect on the decision of product buyers on Vape Move Ngawi. (2) Simultaneously shows that service quality, membership, and price have a significant effect on buyer decisions on Vape Move Ngawi.
A Systematic Review of COVID - 19 Induced Myocarditis - Symptomatology, Prognosis, and Clinical Findings
Authors: Jaiswal Vikash , Nagpal Shavy , E. Labitag Christine Angela , Tayo Janelle , Patel Abhinav , Bryan Lo Kevin , Vijayan Rupalakshmi , F Matos Wanessa , Yaqoob Sadia , Panday Priyanka , Savani Saloni , Alnahas Zeinab , Bhatnagar Arushee , Diaz Yoandra , Dylewski John R. , Khraisat Own , Ghanim Mohammed JM
Published: October 2022

Authors: Vikash Jaiswal, Shavy Nagpal, Christine Angela E.Labitag, Janelle Tayo, Abhinav Patel, Kevin Bryan Lo, Rupalakshmi Vijayan, Wanessa F Matos, Sadia Yaqoob, Priyanka Panday, Saloni Savani, Zeinab Alnahas, Arushee Bhatnagar, Yoandra Diaz, John R. Dylewski, Own Khraisat, Mohammed JM Ghanim. Objective: With the advent of a novel coronavirus in December 2019, several case studies have reported its adversity on cardiac cells. We conducted a systematic review that describes the symptomatology, prognosis, and clinical findings of patients with COVID-19-related myocarditis. Methods: Search engines including PubMed, Google Scholar, Cochrane Central, and Web of Science were queried for "SARS-CoV-2" or "COVID 19" and "myocarditis." PRISMA guidelines were employed, and peerreviewed journals in English related to COVID- 19 were included. Results: This systematic review included 22 studies and 37 patients. Eight patients (36%) were confirmed myocarditis, while the rest were possible myocarditis. Most patients had elevated cardiac biomarkers, including troponin, CRP, CK, CK-MB, and NT-pro BNP. Electrocardiogram results noted tachycardia (47%), left ventricular hypertrophy (50%), ST-segment alterations (41%), and T wave inversion (18%). Echocardiography presented reduced LVEF (77%), left ventricle abnormalities (34%), right ventricle aberrations (12%), and pericardial effusion (71%). Further, CMR showed reduced myocardial edema (75%), non-ischemic patterns (50%), and hypokinesis (26%). The mortality was significant at 25%. Conclusions: Mortality associated with COVID-19 myocarditis appears significant but underestimated. Further studies are warranted to evaluate and quantify patients’ actual prognosis and outcomes with COVID-19 myocarditis.