bluuebunny/crossref_metadata_2025 huggingface dataset:
Flexible Birnbaum–Saunders Distribution
Authors: Martínez-Flórez Guillermo , Barranco-Chamorro Inmaculada , Bolfarine Heleno , Gómez Héctor W.
Published: October 2019

In this paper, we propose a bimodal extension of the Birnbaum–Saunders model by including an extra parameter. This new model is termed flexible Birnbaum–Saunders (FBS) and includes the ordinary Birnbaum–Saunders (BS) and the skew Birnbaum–Saunders (SBS) model as special cases. Its properties are studied. Parameter estimation is considered via an iterative maximum likelihood approach. Two real applications, of interest in environmental sciences, are included, which reveal that our proposal can perform better than other competing models.
Neural Networks Application for Processing of the Data from the FMICW Radars
Authors: Rejfek Lubos , N. Nguyen Tan , Chmelar Pavel , Beran Ladislav , T. Tran Phuong
Published: October 2019

In this paper the results of the Neural Networks and machine learning applications for radar signal processing are presented. The radar output from the primary radar signal processing is represented as a 2D image composed from echoes of the targets and noise background. The Frequency Modulated Interrupted Continuous Wave (FMICW) radar PCDR35 (Portable Cloud Doppler Radar at the frequency 35.4 GHz) was used. Presently, the processing is realized via a National Instruments industrial computer. The neural network of the proposed system is using four or five (optional for the user) signal processing steps. These steps are 2D spectrum filtration, thresholding, unification of the target, target area transforming to the rectangular shape (optional step), and target board line detection. The proposed neural network was tested with sets of four cases (100 tests for every case). This neural network provides image processing of the 2D spectrum. The results obtained from this new system are much better than the results of our previous algorithm.
Identification of Crucial Residues in α-Conotoxin EI Inhibiting Muscle Nicotinic Acetylcholine Receptor
Authors: Ning Jiong , Ren Jie , Xiong Yang , Wu Yong , Zhangsun Manqi , Zhangsun Dongting , Zhu Xiaopeng , Luo Sulan
Published: October 2019

α-Conotoxins (α-CTxs) are small disulfide-rich peptides from venom of Conus species that target nicotinic acetylcholine receptors (nAChRs). The muscle-type nAChRs have been recognized as a potential target for several diseases, such as myogenic disorders, muscle dystrophies, and myasthenia gravis. EI, an α4/7-CTx, mainly blocks α1β1δε nAChRs and has an extra N-terminal extension of three amino acids. In this study, the alanine scanning (Ala-scan) mutagenesis was applied in order to identify key residues of EI for binding with mouse α1β1δε nAChR. The Ala-substituted analogues were tested for their abilities of modulating muscle and neuronal nAChRs in Xenopus laevis oocytes using two-electrode voltage clamp (TEVC) recordings. Electrophysiological results indicated that the vital residues for functional activity of EI were His-7, Pro-8, Met-12, and Pro-15. These changes exhibited a significant decrease in potency of EI against mouse α1β1δε nAChR. Interestingly, replacing the critical serine (Ser) at position 13 with an alanine (Ala) residue resulted in a 2-fold increase in potency at the α1β1δε nAChR, and showed loss of activity on α3β2 and α3β4 nAChRs. Selectivity and potency of [S13A] EI was improved compared with wild-type EI (WT EI). In addition, the structure–activity relationship (SAR) of EI revealed that the “Arg1–Asn2–Hyp3” residues at the N-terminus conferred potency at the muscle-type nAChRs, and the deletion analogue △1–3 EI caused a total loss of activity at the α1β1δε nAChR. Circular dichroism (CD) spectroscopy studies demonstrated that activity loss of truncated analogue △1–3 EI for α1β1δε nAChR is attributed to disturbance of the secondary structure. In this report, an Ala-scan mutagenesis strategy is presented to identify crucial residues that are significantly affecting potency of E1 for mouse α1β1δε nAChR. It may also be important in remodeling of some novel ligands for inhibiting muscle-type nAChRs.
An Introduction to Particle Dark Matter
Authors: Profumo Stefano , Giani Leonardo , Piattella Oliver F.
Published: October 2019

We review the features of Dark Matter as a particle, presenting some old and new instructive models, and looking for their physical implications in the early universe and in the process of structure formation. We also present a schematic of Dark Matter searches and introduce the most promising candidates to the role of Dark Matter particle.
Eradication of Vancomycin-Resistant Enterococci by Combining Phage and Vancomycin
Authors: Shlezinger Mor , Coppenhagen-Glazer Shunit , Gelman Daniel , Beyth Nurit , Hazan Ronen
Published: October 2019

Currently, effective options are needed to fight vancomycin-resistant Enterococcus faecalis (VRE). The present study shows that combinations of phage and vancomycin are highly efficient against VRE, despite being resistant to the antibiotic. Vancomycin-phage EFLK1 (anti-E. faecalis phage) synergy was assessed against VRE planktonic and biofilm cultures. The effect of the combined treatment on VRE biofilms was determined by evaluating the viable counts and biomass and then visualized using scanning electron microscopy (SEM). The cell wall peptidoglycan was stained after phage treatment, visualized by confocal microscopy and quantified by fluorescence activated cell sorting (FACS) analysis. The combined treatment was synergistically effective compared to treatment with phage or antibiotic alone, both in planktonic and biofilm cultures. Confocal microscopy and FACS analysis showed that fluorescence intensity of phage-treated bacteria increased eight-fold, suggesting a change in the peptidoglycan of the cell wall. Our results indicate that with combined treatment, VRE strains are not more problematic than sensitive strains and thus give hope in the continuous struggle against the current emergence of multidrug resistant pathogens.
Ultrastructural Aspects of Photodynamic Inactivation of Highly Pathogenic Avian H5N8 Influenza Virus
Authors: Korneev Denis , Kurskaya Olga , Sharshov Kirill , Eastwood Justin , Strakhovskaya Marina
Published: October 2019

Ultrastructural studies revealing morphological differences between intact and photodynamically inactivated virions can point to inactivation mechanisms and molecular targets. Using influenza as a model system, we show that photodynamic virus inactivation is possible without total virion destruction. Indeed, irradiation with a relatively low concentration of the photosensitizer (octacationic octakis(cholinyl) zinc phthalocyanine) inactivated viral particles (the virus titer was determined in Madin Darby Canine Kidney (MDCK) cells) but did not destroy them. Transmission electron microscopy (TEM) revealed that virion membranes kept structural integrity but lost their surface glycoproteins. Such structures are known as “bald” virions, which were first described as a result of protease treatment. At a higher photosensitizer concentration, the lipid membranes were also destroyed. Therefore, photodynamic inactivation of influenza virus initially results from surface protein removal, followed by complete virion destruction. This study suggests that photodynamic treatment can be used to manufacture “bald” virions for experimental purposes. Photodynamic inactivation is based on the production of reactive oxygen species which attack and destroy biomolecules. Thus, the results of this study can potentially apply to other enveloped viruses and sources of singlet oxygen.
Environmental Contamination and Hygienic Measures After Feline Calicivirus Field Strain Infections of Cats in a Research Facility
Authors: Spiri Andrea Monika , Meli Marina Luisa , Riond Barbara , Herbert Imogen , Hosie Margaret J. , Hofmann-Lehmann Regina
Published: October 2019

Feline calicivirus (FCV) can cause painful oral ulcerations, salivation, gingivitis/stomatitis, fever and depression in infected cats; highly virulent virus variants can lead to fatal epizootic outbreaks. Viral transmission occurs directly or indirectly via fomites. The aim of this study was to investigate the presence and viability of FCV in the environment after sequential oronasal infections of specified pathogen-free cats with two FCV field strains in a research facility. Replicating virus was detected in saliva swabs from all ten cats after the first and in four out of ten cats after the second FCV exposure using virus isolation to identify FCV shedders. In the environment, where cleaning, but no disinfection took place, FCV viral RNA was detectable using RT-qPCR on all tested items and surfaces, including cat hair. However, only very limited evidence was found of replicating virus using virus isolation. Viral RNA remained demonstrable for at least 28 days after shedding had ceased in all cats. Disinfection with 5% sodium bicarbonate (and IncidinTM Plus) and barrier measures were effective in that no viral RNA was detectable outside the cat rooms. Our findings are important for any multicat environment to optimize hygienic measures against FCV infection.
Adjuvant Strategies for Lactic Acid Bacterial Mucosal Vaccines
Authors: Vilander Allison C. , Dean Gregg A.
Published: October 2019

Lactic acid bacteria (LAB) are Gram-positive, acid-tolerant bacteria that have long been used in food fermentation and are generally recognized as safe (GRAS). LAB are a part of a normal microbiome and act as probiotics, improving the gastrointestinal microbiome and health when consumed. An increasing body of research has shown the importance of the microbiome on both mucosal immune heath and immune response to pathogens and oral vaccines. Currently, there are few approved mucosal vaccines, and most are attenuated viruses or bacteria, which necessitates cold chain, carries the risk of reversion to virulence, and can have limited efficacy in individuals with poor mucosal health. On account of these limitations, new types of mucosal vaccine vectors are necessary. There has been increasing interest and success in developing recombinant LAB as next generation mucosal vaccine vectors due to their natural acid and bile resistance, stability at room temperature, endogenous activation of innate and adaptive immune responses, and the development of molecular techniques that allow for manipulation of their genomes. To enhance the immunogenicity of these LAB vaccines, numerous adjuvant strategies have been successfully employed. Here, we review these adjuvant strategies and their mechanisms of action which include: Toll-like receptor ligands, secretion of bacterial toxins, secretion of cytokines, direct delivery to antigen presenting cells, and enterocyte targeting. The ability to increase the immune response to LAB vaccines gives them the potential to be powerful mucosal vaccine vectors against mucosal pathogens.
Next-Generation Whole-Cell Pneumococcal Vaccine
Authors: Morais Victor , Texeira Esther , Suarez Norma
Published: October 2019

Streptococcus pneumoniae remains a major public health hazard. Although Pneumococcal Conjugate Vaccines (PCVs) are available and have significantly reduced the rate of invasive pneumococcal diseases, there is still a need for new vaccines with unlimited serotype coverage, long-lasting protection, and lower cost to be developed. One of the most promising candidates is the Whole-Cell Pneumococcal Vaccine (WCV). The new generation of whole-cell vaccines is based on an unencapsulated serotype that allows the expression of many bacterial antigens at a lower cost than a recombinant vaccine. These vaccines have been extensively studied, are currently in human trial phase 1/2, and seem to be the best treatment choice for pneumococcal diseases, especially for developing countries.
Local Factors Determining Spatially Heterogeneous Channel Migration in a Low-Energy Stream
Authors: Menting Foeke , Meijles Erik W.
Published: October 2019

Since the 1990s, nature and water management policies have attempted to re-create natural rivers systems by mimicking curvy meandering planforms, based on the assumption that meandering is the natural channel-forming process. However, in low-energy river systems, the extent to which meandering plays a natural role is often minimal. This study aims to quantify contemporary lateral migration in the low-energy irregular sinuous lowland river system of the Drentsche Aa, The Netherlands, and to determine the factors influencing lateral channel migration in a heterogeneous valley fill. Although the river is classified as laterally immobile based on an empirical stability diagram, field observations prove that erosion and deposition are currently occurring. By analyzing historical and present-day maps, it was shown that lateral migration was highly spatially variable for the period 1924–2005. Sinuosity and valley gradient are not correlated to lateral migration rates, suggesting they are not a measure of lateral migration in the case study area, which is in line with the literature. Based on geomorphological and soil map analyses, it was shown that lateral migration rates are significantly higher in valley fills of aeolian sands than in clastic alluvial deposits, which on their turn are significantly higher than in peaty environments. Therefore, local conditions appear to be dominant over other factors such as stream power and bed grain size. These findings are important for river rehabilitation of low-energy rivers, because it shows that local valley fill conditions can greatly influence active lateral migration in the river.
Strategies, Processes, and Results for the Future Water Supply of the Växjö Municipality: Evaluation of an Evidence-Based Case Study of Long-Term Strategies within the Water and Wastewater Sector in Sweden
Authors: Najar Nasik , Persson Kenneth M
Published: October 2019

In 2009, the Bergaåsen Water Supply Scheme was put into operation to ensure the future drinking water supply of two municipalities in southern Sweden. Bergaåsen replaced two vulnerable water treatment plants. It was implemented in an environment that was characterized by sensitive recipients and limited access to water. This article aims to analyze how strategies were developed to meet sustainability requirements, if this solution has ensured good quantity and high quality after ten years of operation, and the extent of the project’s economic impact on consumers. The project was analyzed as an evidence-based case study using semi-structured interviews, surveys, and document analyses. The study found that the chosen options succeeded in guaranteeing outstanding quality and secure delivery. Over 90% of water users were satisfied and had trust in it, and less than 3% were dissatisfied. The design time for withdrawal capacity has been extended from 30 to 50 years through planned measures. The study clarifies also that, due to some externalities, there has been virtually no economic impact on users. Bergaåsen is a clear case for the value of developing long-term strategies and implementing them in real life.
Three-Dimensional Numerical Simulation of Dam Discharge and Flood Routing in Wudu Reservoir
Authors: Rong Youtong , Zhang Ting , Peng Ling , Feng Ping
Published: October 2019

The main objectives of the present work are to investigate the hydraulic characteristics of the dam discharge flow and its impact downstream. Building information modeling technology is adopted to generate the terrain entity and hydraulic structures. The calculation of the dam discharge and flood routing simulation is achieved by employing Reynolds-Averaged Navier-Stokes equations with the RNG k-ε eddy viscosity model for its turbulence closure, as well as the Volume of Fluid method. An urban flood experiment and the field measurement records are utilized and validated the model accuracy. The flow field is obtained to assess the dam working conditions under different water levels. The results show that the maximum downstream flow depth, the maximum discharge capacity and the hydraulic jump length under normal water level is 18.6 m, 13,800 m3/s, and 108 m, respectively. The dam satisfies the safety demand under different water levels but close attention should be paid to the dam foundation, especially around the incident points of the discharge flow. Complex turbulent flow patterns, including collision, reflection, and vortices, are captured by three-dimensional simulation. The numerical simulation can assist the reservoir management vividly, so as to guarantee the stability of the dam operation.
Evapotranspiration from Horizontal Subsurface Flow Constructed Wetlands Planted with Different Perennial Plant Species
Authors: Milani Mirco , Marzo Alessia , Toscano Attilio , Consoli Simona , Cirelli Giuseppe Luigi , Ventura Delia , Barbagallo Salvatore
Published: October 2019

This paper presents the results of an experiment carried out in Southern Italy (Sicily) on the estimation evapotranspiration (ET) in pilot constructed wetlands planted with different species (Chrysopogon zizanioides, Myscanthus x giganteus, Arundo donax, Phragmites australis, and Cyperus papyrus). In the two monitored growing seasons, reference ET0 was calculated with the Penman-Monteith formula, while actual ET and crop coefficients were measured through a water balance and the FAO 56 approach, respectively. The highest average seasonal ET value was observed in Phragmites australis (17.31 mm d−1) followed by Arundo donax (11.23 mm day−1) Chrysopogon zizanioides (8.56 mm day−1), Cyperus papyrus (7.86 mm day−1), and Myscanthus x giganteus (7.35 mm day−1). For all plants, crop coefficient values showed different patterns in relation to growth stages and were strongly correlated with phenological parameters. Myscanthus x giganteus and Arundo donax showed a water use efficiency values significantly higher than those observed for the other tested species. Results of this study may contribute to select appropriate plant species for constructed wetlands located in semi-arid regions, especially when the use of reclaimed water and/or the use of aboveground biomass are planned.
Forecasting Groundwater Level for Soil Landslide Based on a Dynamic Model and Landslide Evolution Pattern
Authors: Duan Gonghao , Chen Deng , Niu Ruiqing
Published: October 2019

The occurrence and migration of groundwater is a key natural factor that directly affects the stability of landslides, and rainfall has a large effect on the groundwater level in soil landslides. This study used the Baijiabao landslide in the Three Georges area of China as the research subject and used a combination of more than seven years of rainfall and GPS (Global Positioning System) monitoring data from 2007 to 2013. We applied the K-means clustering method to classify one cycle of the evolution stage into three classes based on the relative displacement of the main sliding surface of the landslide. To illustrate the relationship between the three landslide evolution divisions and the dynamic indicators, we identified rainfall factors that correspond to the actual change in the landslide using the minimal description length principle method. Based on the relationship between the actual deformation stage of the landslide and the rainfall factor from historical monitoring, the mean absolute error of the dynamic exponential smoothing model was 0.053, and the correlation coefficient was 0.929. The size of the smoothness index could be modified in real-time to achieve dynamic correction, which indicates that the model exhibited high reliability and confirmed the usefulness of the proposed model for forecasting groundwater level changes based on deep-seated soil landslide type.
Potential Benefits of Managed Aquifer Recharge MAR on the Island of Gotland, Sweden
Authors: Dahlqvist Peter , Sjöstrand Karin , Lindhe Andreas , Rosén Lars , Nisell Jakob , Hellstrand Eva , Holgersson Björn
Published: October 2019

The Island of Gotland (3000 km2), east of mainland Sweden, suffers from insufficient water availability each summer. Thin soils and lack of coherent reservoirs in the sedimentary bedrock lead to limited reservoir capacity. The feasibility of Managed Aquifer Recharge (MAR) is explored by identifying suitable areas and estimating their possible contribution to an increased water availability. MAR is compared to alternative water management measures, e.g., increased groundwater abstraction, in terms of costs and water availability potential. Results from GIS analyses of infiltration areas and groundwater storage, respectively proximity to surface water sources and surface water storage were classified into three categories of MAR suitability. An area of ca 7700 ha (2.5% of Gotland) was found to have good local conditions for MAR and an area of ca 22,700 ha (7.5% of Gotland) was found to have moderate local conditions for MAR. These results reveal the MAR potential on Gotland. The water supply potential of MAR in existing well fields was estimated to be about 35% of the forecasted drinking water supply and 7% of the total water demand gap in year 2045. It is similar in costs and water supply potential to increased surface water extraction.
Photocatalytic Treatment of Pharmaceuticals in Real Hospital Wastewaters for Effluent Quality Amelioration
Authors: Konstas Panagiotis-Spyridon , Kosma Christina , Konstantinou Ioannis , Albanis Triantafyllos
Published: October 2019

The presence of pharmaceutically active compounds (PhACs) in the wastewater effluents has confirmed that conventional wastewater treatment technologies are not sufficiently effective in the pharmaceuticals’ removal. The objective of the present study was to evaluate and compare the photocatalytic degradation of PhACs using TiO2-P25, graphitic carbon nitride (g-C3N4, CN) and a heterojunction of perovskite strodium titanate and graphitic carbon nitride SrTiO3/g-C3N4 (20% g-C3N4, 20CNSTO) photocatalytic materials, in hospital wastewater effluents, by simulated solar irradiation. The experiments were performed by using real wastewater samples collected from the university hospital wastewater treatment plant (WWTP) effluent of Ioannina city (Northwestern Greece) and inherent pharmaceutical concentration levels. The analysis of the samples was accomplished by solid phase extraction followed by liquid chromatography-Orbitrap high-resolution mass spectrometry. In the cases of TiO2 and CN, more than 70% of the initial concentration (e.g., venlafaxine) was degraded after 90 min, while 20CNSTO presented lower photocatalytic performance. Furthermore, some compounds were sporadically detected (e.g., fluoxetine) or their concentrations remained stable during the photocatalytic treatment time period (e.g., trimethoprim). In total 11 transformation products (TPs) were formed along the degradation processes and were identified by using liquid chromatography high resolution mass spectrometry.
Investigation of Trends, Temporal Changes in Intensity-Duration-Frequency (IDF) Curves and Extreme Rainfall Events Clustering at Regional Scale Using 5 min Rainfall Data
Authors: Bezak Nejc , Mikoš Matjaž
Published: October 2019

High-frequency rainfall data is needed in different practical hydrologic applications, such as the construction of the intensity-duration-frequency curves (IDF). This paper presents an investigation of trends (station-wise and regional) for several rainfall durations that were constructed based on the 5 min rainfall data. Moreover, changes in IDF results for two 22-year sub-samples were also analyzed. Additionally, changes in extreme events clustering at the regional scale were also analyzed. Ten rainfall stations (44 years of data 1975–2018) located in Slovenia (central EU, approx. 20,000 km2) were used in this study. Results indicate that no clear pattern in the detected trends can be found based on the analyzed stations. However, all the statistically significant trends at the significance level of 0.05 for the 5 min rainfall data were negative. Moreover, regional trends for this duration were also statistically significant. The changes in the design rainfall events between two equal sub-samples (1975–1996, 1997–2018) were between −30% and 60%. The investigation of changes in extreme rainfall event clustering indicated that extreme 5, 30, and 60 min events could more frequently occur a few days earlier in spring or summer compared to the past period. On the other hand, longer duration events (i.e., 360 and 720 min) tend to more frequently occur a few days later in autumn compared to the past. In most cases, changes are not statistically significant.
Ganz selbstbewusst und dennoch ganz anders. Überlegungen zum Verhältnis von mittelalterlicher und moderner Individualität am Beispiel deutscher und italienischer Familienbücher
Authors: Arlinghaus Franz-Josef
Published: October 2019

Fourteenth to sixteenth century Libri di Famiglia and housebooks (Hausbücher) – that of the jurist Giovanni Gaspare da Sala from Milan and the merchants Ugolino dì Nicolò Martelli and Goro Dati from Florence as well as those of Lucas Rem from Augsburg and Hermann von Weinsberg from Cologne – are analyzed in this paper. These writings are compared with high medieval autobiographical texts (Guibert von Nogent, Abaelard) and with modern autobiographies (namely Roland Barthes). At a first glance, high medieval autobiographical texts seem to be much more explicit in respect of the authors ‘self’ than the Libri di famiglia and housebooks of the late middle ages and early modern times.Drawing on theoretical approaches developed by literary studies (Literaturwissenschaften) and sociology, which suggest a different reading of our late medieval sources, not only those parts of the Libri di famiglia that explicitly deal with the authors self are taken into account. Rather, the whole book (including the notes that inform about business transactions and everyday political events) are seen as part of a self-construction. The analysis then does not only make use of these often neglected contents of the libri di famiglia and housebooks, but also looks at the form of the written text the language used. It turned out that the respective authors of the housebooks and Libri di famiglia creatively combine different styles of writing (in form as well as in content), thus documenting their self-esteem and self-consciousness.However, the overall paradigm that is revealed is that of inscribing one´s own self in society, constructing the ‘I’ as an important and outstanding part of the world (labeled ‘inclusion individuality’). Notwithstanding all differences, the late medieval autobiographical texts share this paradigm with the high medieval sources mentioned. In sharp contrast to that, modern autobiographies place the self in opposition to or even outside society, not necessarily providing it with more self-confidence, but with a completely different attitude towards the ‘I’ and very distinct concepts about the self. The reason for this is not so much seen in developments of higher self-reflection but in structures of society that provide or do not provide a place for the self in society.
Calcite et rôle possible du CO2 dans la genèse des roches hyperalcalines et agpaïtiques du Velay oriental (Haute-Loire, Massif central français)
Authors: Batard Francine , Mergoil-Daniel Juliette , Mergoil Jean
Published: October 2019

Dans la série alcaline sodique forte du Velay, on met en évidence le caractère mixte de certaines phonolites : début de cristallisation miaskitique auquel succède un stade agpaïtique. On rapproche ce fait de la présence fréquente de calcite dans ces roches et les trachytes associés. La position particulière de la calcite (enfermée dans le cœur plagioclasique de phénocristaux feldspathiques) suggère l'attaque du plagioclase par CO₂ qui libérerait sélectivement Ca et Na. Certaines phonolites agpaïtiques du Velay pourraient ainsi provenir de liquides trachytiques par l'effet de la cristallisation fractionnée couplée avec un processus d'autofénitisation, carbonate et roches alcalines apparaissant dans ce cas comme deux effets d'une même cause. Confirmation du rôle du CO₂ est apportée par l'abondance des inclusions fluides à CO₂ pur dans les feldspaths.
PERLAKUAN AKUNTANSI TRANSAKSI DANA PESERTA PRODUK TAKAFUL PENDIDIKAN PADA PT ASURANSI TAKAFUL KELUARGA CABANG BANJARMASIN
Authors: Machfiroh Ines Saraswati
Published: October 2019

Asuransi pendidikan merupakan salah satu produk dari asuransi Keluarga(jiwa) yang mengandung unsur saving. Selain itu unsur preminya terdiridari rekening tabungan peserta dan rekening dana tabarruâ€™, bagi hasilnyadilakukan sesuai dengan skim bagi hasil, dan sumber pembayaran klaimmeninggal dunia diperoleh dari akumulasi rekening dana tabarruâ€™parapeserta. Klaim yang dapat diajukan peserta pada asuransi pendidikanterdiri dari klaim nilai tunai, klaim meninggal dunia, klaim habis kontrak,dan klaim tahapan manfaat.Produk Takaful Pendidikan merupakan produk yang menawarkan tahapanmanfaat pendidikan bagi penerima hibah (anak) mulai masuk TK, masukSD, masuk SMP, masuk SMU sampai dengan Perguruan Tinggi. Perlakuanakuntansi pada produk Takaful Pendidikan untuk premi tahun pertamadialokasikan pada rekening kewajiban manfaat polis masa depan (danatabarruâ€™) dan rekening dana pemegang polis unit link (tabungan peserta),untuk bagi hasil dibagikan sesuai dengan skim bagi hasil dan dicatat dalamrekening dana pemegang polis unit link (bagi hasil), dan untuk klaim tahunpertama hanya terdiri dari klaim nilai tunai dan klaim meninggal dunia.Dimana masing-masing jenis klaim tersebut akan mempengaruhi tahapanmanfaat yang akan diterima peserta.Kata Kunci: premi, klaim, tabarruâ€™
TEKNIK KONVENSIONAL PENGGUNAAN TUMBUHAN OBAT DI KAWASAN ESTUARIA TAKISUNG
Authors: Lestari Ema
Published: October 2019

Tumbuhan obat adalah tumbuhan yang memiliki khasiat obat dan digunakansebagai obat dalam penyembuhan maupun pencegahan penyakit. Di daerahTakisung terdapat kawasan estuaria.Dikawasan tersebut ditumbuhi pepohonan,tumbuhan herba dan semak yang berpotensi sebagai tanaman obat.Masyarakatdaerah setempat menggunakan tumbuhan obat sebagai alternatif dalampengobatan, karena banyak ditemukan tumbuhan obat di sekitarmereka.Penelitian ini bertujuan untukmendapatkan informasi tentangbagaimana teknik penggunaan tumbuhan obat dikawasan estuaria Takisungoleh masyarakat di daerah tersebut.Metode yang digunakan dalam penelitianini adalah metode diskriptif, dengan terjun secara langsung ke lapangan padakawasan kiri dan kanan bantaran estuaria Pantai Takisung KecamatanTakisung Kabupaten Tanah Laut. Hasil penelitian menunjukkan bahwatumbuhan berkhasiat obat yang ditemukan di kawasan estuaria Takisung yangdiketahui dan digunakan oleh masyarakat setempat terdapat 15 jenistumbuhan.Teknik konvensional penggunaan tumbuhan obat masyarakat dikawasan estuaria meliputi:1bahan di cuci bersih kemudian di rebus bersamaan,setelah dingin air rebusan tersebut disaring kemudian diminum,2bahan dicucibersih terlebih dahulu kemudian ditumbuk, setelah itu dioleskan, 3bahandipanggang diatas api kemudian diusapkan, 4bahan diparut kemudian diperas,air yang dihasilkan diminum, 5bahan direbus kemudian dicucikan, 6bahandirendam dalam air terus dan diminum, 7bahan direbus dan dimakan, 8bahancairan yang pada bagian tumbuhan kemudian diteteskan, 9bahandirebus danair rebusan diminum, 10bahan dilumatkan hingga halus dan di oleskan, 11bahandibersihkan lalu ditumbuk sampai halus, lalu dicampurkan dengan bahan lainlalu dioleskan, 12bahan dikeringkan kemudian direbus, lalu air rebusannyadiminum, 13bahan ditumbuk kemudian dicampurkan dengan bahan lainkemudian diusapkan, 14bahan diremas-remas dan di usapkan.Kata Kunci: Tumbuhan Obat, Kawasan Estuaria, Teknik Konvensional
Estrategias Administrativas y Financieras: herramientas clave para una gestión eficiente
Authors: Mosquera Choco Edgar Orlando , Erazo Álvarez Juan Carlos , Narváez Zurita Cecilia Ivonne
Published: October 2019

Recibido: 10 de agosto de 2019Aprobado: 30 de agosto de 2019El presente artículo, tiene como objetivo establecer estrategias administrativas y financieras con el fin de disminuir el nivel de endeudamiento en la empresa SERSEIVI Servicio de Seguridad y Vigilancia Cía. Ltda. Se utilizaron los métodos Descriptivo-Explicativo ya que se analizó las causas que originan la situación de estudio. El tipo de investigación empleado es no experimental, el enfoque es cualitativo a través de la investigación exploratoria, recopilando datos aplicando varias técnicas como cuestionarios, observaciones, entrevistas, foro grupal, etc. con la finalidad de llevar a cabo un análisis más amplio y lograr una mejor comprensión de las situaciones. Basado en los resultados obtenidos se aplicó el enfoque cuantitativo evidenciado en los resultados a través de los cuales fue posible definir una propuesta que permita disminuir el sobre endeudamiento.
La influencia de las 4Ps en el Marketing Digital para la Cooperativa de Ahorro y Crédito JEP
Authors: Trelles Méndez Elizabeth Magdalena , Erazo Álvarez Juan Carlos , Narváez Zurita Cecilia Ivonne
Published: October 2019

Recibido: 10 de agosto de 2019Aprobado: 30 de agosto de 2019El Marketing es una de las disciplinas con mayor campo de acción en el mundo profesional, se enfoca en entender las necesidades de un público con la finalidad de impulsar las ventas. Llega hasta la forma adecuada de comunicación para crear un vínculo entre las personas y la marca. La Unidad de análisis de esta investigación es la Cooperativa de Ahorro y Crédito "Juventud Ecuatoriana Progresista" Ltda., (JEP) cuyo problema es la deficiente colocación de tarjetas de crédito que se originan principalmente por ser un producto que está en el ciclo de desarrollo, para mejorar esta situación se plantean estrategias de marketing digital enfocadas en las 4Ps. La Investigación tiene un enfoque mixto, es de tipo exploratoria y descriptiva, no experimental y probabilística y según su alcance es descriptiva. Como resultados de la investigación se evidenció falencias especialmente en la gestión digital lo que no permite dar una respuesta eficaz y a lo que se plantean estrategias en función al tipo de organización.
Clima organizacional en el desempeño laboral de las instituciones públicas gubernamentales
Authors: Guerrero Chávez Francisca Fernanda , Neira Altamirano Luis Fernando , Vásconez Vásconez Henry David
Published: October 2019

Recibido: 10 de agosto de 2019Aprobado: 30 de agosto de 2019Se tuvo por objetivo determinar la relación de los tipos de clima organizacional en el desempeño laboral de las instituciones públicas gubernamentales. Con un tipo de investigación es correlacional, se fundamentó en un diseño no experimental, transeccional, la población estuvo constituida por un conjunto de 112 sujetos de investigación, que ocupan el cargo de personal administrativo en instituciones públicas gubernamentales de la ciudad de Manta, durante el primer semestre del año 2019. Los climas organizacionales predominantes son el autoritario – explotador y el participativo – en grupo, lo cual evidencia que los empleados actúan favorablemente cuando se generan este tipo de clima, favoreciéndose en mayor significancia cuando se emplea el participativo de grupo, por cuanto permite que puedan generar aportes que son tenidos en cuenta para el cumplimiento de metas institucionales.
El clima organizacional y su incidencia en la motivación del Talento Humano
Authors: Valencia Naranjo Diana Elizabeth , Erazo Álvarez Juan Carlos , Narváez Zurita Cecilia Ivonne
Published: October 2019

Recibido: 11 de agosto de 2019Aprobado: 28 de agosto de 2019El talento humano es el principal elemento de una organización, donde el Clima organizacional y la motivación son fundamentales para el éxito y la consecución de sus objetivos. Problemas precisamente identificados en la Unidad de análisis de la presente investigación. Para la verificación de la problemática identificada se utilizó un diseño de investigación mixto exploratorio secuencial (dexplos) derivativa ya que se realizó un análisis cualitativo de los datos recolectados cuantitativamente, según el enfoque fue descriptiva. Los resultados obtenidos dan cuenta de la importancia de generar políticas para que sean aplicadas de forma constante y permanente mediante la utilización de un plan de incentivos y recompensas.
El examen especial como proceso de control: fases y aplicación práctica en el sec-tor público
Authors: Figueroa Hurtado Diana Paulina , Narváez Zurita Cecilia Ivonne , Erazo Álvarez Juan Carlos
Published: October 2019

Recibido: 1 de septiembre de 2019Aprobado: 30 de septiembre de 2019El examen especial (EE) permite detectar hallazgos en las instituciones auditadas,  además analiza la eficiencia, eficacia, efectividad y economía en la administración. El presente artículo científico se basa en la problemática de como evaluar la administración de talento humano del Registro de la Propiedad del cantón Cuenca; para lo cual se ha planteado como objetivo la aplicación de un EE al proceso administrativo en el período enero a diciembre de 2018, con fines de verificación del cumplimiento de este, de acuerdo a la normativa vigente. Se aplicó un estudio de tipo experimental, ya que se ejecutó un EE para identificar el cumplimiento de los procesos; con lo que se pudo determinar que la entidad no cumple de manera íntegra la ejecución del programa de capacitación y de igual manera inobserva la normativa referente a la presentación del reporte de las declaraciones patrimoniales a la Contraloría General del Estado Ecuatoriano.
Factores determinantes del costeo ABC ABM en la industria de textiles. Caso: Fábrica Textil Multijeans
Authors: Mogrovejo Juela Andrés Alejandro , Narváez Zurita Cecilia Ivonne , Erazo Álvarez Juan Carlos
Published: October 2019

Recibido: 1 de septiembre de 2019Aprobado: 30 de septiembre de 2019En la actualidad, las empresas experimentan cambios constantes debido a la necesidad de buscar la mejora continua y el aprovechamiento de sus recursos, es por esto que se han vuelto más innovadoras en el entorno que les rodea y, tanto los productos que  ofertan como los servicios que prestan, incorporan dentro de sus actividades, procesos de reingeniería capaces de poder acoplarse y restablecer problemas que afrontan las empresas a nivel nacional e internacional. En base a lo expuesto, se planteó un sistema de costos ABC/ABM para la empresa productora de pantalones Multijeans, respaldado en la obtención de información confiable y oportuna que le permita tomar decisiones; es así que, el sistema de costos basado en actividades, es la herramienta propicia para este tipo de empresa, por cuanto se propone una guía para el manejo de costos y el control de los recursos que se llevan a cabo dentro del proceso productivo y los demás procesos.
Sistema de control interno con enfoque en la ISO 9001: 2015 en la bananera Monterrey
Authors: Murillo Apolo Lizbeth Andrea , Narváez Zurita Cecilia Ivonne , Erazo Álvarez Juan Carlos
Published: October 2019

Recibido: 1 de septiembre de 2019Aprobado: 30 de septiembre de 2019El presente artículo tiene como objetivo diseñar un sistema de control interno bajo el enfoque de las normas ISO 9001:2015. Para ello, se desarrolló un análisis de los sistemas de control interno, los componentes del informe Coso (Committee of Sponsoring Organizations of the Treadway Comission), y las ISO 9001-2015. Se pudo concluir que la articulación de estas teorías permite generar sistemas de control interno que garantizan la eficiencia y eficacia de las operaciones en la organizaciones. La investigación permitió además evaluar las actividades de control interno que se ejecutan en la bananera Monterrey localizada en la provincia de El Oro, Ecuador,  en donde se estableció que su riesgo de control es moderado y su nivel de confianza bajo. Ante estos resultados, finalmente se planteó un nuevo sistema de control interno que genere beneficios relacionados con el uso de los recursos, la optimización de los procesos y el aumento de la satisfacción del cliente.
USE OF CERITA RAKYAT NUSANTARA APP IN DEVELOPING ORAL INTERACTION SKILLS
Authors: Ahmad Jumilah , Samsuri Sabrina
Published: October 2019

This research paper describes efforts to use the Cerita Rakyat Nusantara app (an interactive e-book of Malay Archipelago Folklore) to help build oral interaction skills among primary 2 students. In an effort to attract digital natives to interact orally in standard Malay Language, it is a challenge for Singapore Malay Language teachers. This task is turning to challenge as there is a need for relevant and appropriate materials to encourage these digital natives to speak proficiently and confidently. This study aimed to see how the use of the Cerita Rakyat Nusantara app could assist build oral interaction skills among the lower primary students (primary 2 students). The study subjects consisted of 23 primary 2 students. Researchers had begun the study by conducting a student survey followed by an oral interactions assessment before students were introduced to the Cerita Rakyat Nusantara app. At the end of the study, students fill out the reflection form. Additionally, six students were also interviewed via video recording. In line with the process of providing students with skills of the digital age, researchers are adopting the use of Information and Communication Technology (ICT) tools to encourage accurate and creative use of language and information. Findings from the study successfully showed students' interest in the featured app. Based on six video recordings of student interviews, they were more confident and proficient to interact after using the Cerita Rakyat Nusantara app as a means to gather ideas. It helps to sharpen the students' listening skills and the process of integrating listening skills with reading, indirectly helps learners' speaking skills as observed from our studies. Overall, the findings suggest that students liked the Cerita Rakyat Nusantara app. In conclusion, the use of the Cerita Rakyat Nusantara app helps build oral interaction skills among lower primary school students based on this critical study.
QUALITATIVE INSIGHT ON THE IMPACT OF LEADERS’ COMPETENCIES TO MOSQUE PERFORMANCE
Authors: Zakaria Azfahanee , Ngah Kamaruddin
Published: October 2019

Mosque plays an important role in molding and creating beautiful success ummah. In the days of Prophet Muhammad s.a.w. the mosque is known and acts as a central place for all Muslims to practice religious rituals as well as other social activities. However, in Malaysia, the mosque is now seen as a place meant for religious rituals only and the activities held does not attract many attendees. This research aims to understand what are the core competencies which will have a significant impact on mosque performance. This is seen as necessary as having leaders with the identified core competencies will uplift the mosque institution to a higher level professionally. The research adopts a qualitative method and eighteen mosque leaders representing six mosques in the state of Kedah have been selected based on the recommendation by the religious state office respectively. Data would be collected using the interview and observation method. The result of the study aims to assist Kedah State Religious to strengthen and identify the competencies needed by the mosque leaders in managing the mosque effectively.
ECONOMIC EFFICIENCY OF MILK PRODUCTION IN AGRICULTURAL ENTERPRISES
Authors: Vasylchenko Oleksii
Published: October 2019

Introduction. The development of dairy production, which the consumption of milk and dairy products depends on, should be based on the effective functioning of market-oriented agrarian formations. The experience of the recent years indicates the creation of a powerful group of dairy farms, whose share in production is constantly increasing. The article analyses the dynamics of the main indicators of the economic efficiency of milk production in agricultural enterprises of Ukraine. The structure of production costs is considered. The directions of their reduction are determined. Grouping of agricultural enterprises is made depending on the number of cows, their productivity, concentration and specialization of production.
Purpose. The article aims to develop methodological principles for estimation the impact of some factors on the economic efficiency of milk production in agricultural enterprises in Ukraine.
Results. It has been established that milk production as a whole has become profitable during the last decade, especially for groups of farms with 500 and more cows. It has been proved that in case of impossibility of influence on the purchase price, one of the directions of maintenance of profitability is the increase of cows’ productivity. The main factors that influence the economic efficiency of milk production have been identified. They are the concentration and specialization of production, the deepening of which will provide profitability to ensure expanded reproduction, intensification of production, introduction of innovative technologies, increase the competitiveness of domestic dairy farms.
LOGICAL HIERARCHY OF TERMS IN THE SYSTEM OF ECONOMIC SECURITY
Authors: Danilova Elvira
Published: October 2019

Introduction. Instability and uncertainty of the environment creates threats, dangers and risks for enterprises. The higher the intensity of their effects, the more active becomes the policy of the company in neutralizing their negative effects. The formation of the system of economic protection from negative effects of threats, hazards and risks needs to be clarified as the economic essence of these concepts, as well as their logical ordering in the process of interaction with the enterprise.
Purpose. The article aims to summarize scientifically the logical ordering of terms that form the system of economic security.
Method (methodology). To achieve the purpose of the research we have used the following methods: method of process approach to scientific research, methods of analysis and synthesis to the formation of the logical chain of terms, method of grouping to identify threats, hazards and risks.
Results. The paper has summarized the scientific approaches to understanding the essence of economic security. It logically arranges the concept of threat, danger and risk, which will allow the formation of a system of assessment and management of economic security. The identification of existing threats and risks existing at the current stage of economic development for enterprise activity has allowed formulating a set of factors of influence and determining the direction of their actions.