bluuebunny/crossref_metadata_2025 huggingface dataset:
Compulsory vaccination: Public benefit or individual’s right limitation
Authors: Yastrebov Oleg A.
Published: March 2022

Mass vaccination and its controversial assessments have become key issues under the COVID-19 pandemic. Outbreaks of diseases and popularity of anti-vaccination movements require a study of legal foundations for medical interventions and freedom restrictions which are considered as the result of serious risks to health and sanitary-epidemiological well-being of the population. The question is what should be prioritized - paternalistic powers of the state or individual rights and freedoms to decide what risks to take. In terms of responsibility distribution, people often consider vaccines as more dangerous than infectious diseases, which makes compulsory vaccination a legal phenomenon of particular importance. In the contemporary legislation, there are various national approaches to the individual autonomy and freedoms. In some countries, vaccination is directly linked to the possibility to study (USA), in others it is associated with public health (Australia), financial sanctions (Poland) or freedoms limitations (Pakistan). In terms of public health ethics, vaccination is similar to the use of seat-belts in cars, and compulsory vaccination policy is ethically justified by the same reasons as mandatory seat-belt laws: at first, they were met with great opposition; later the use of seat belts acquired the significance of not only a legal but also a social norm precisely because it was made mandatory. The similar approach is applicable to vaccination: the policy of compulsory vaccination can make it a social norm. However, in the legal perspective, compulsory vaccination is a compulsory medical intervention which raises the question about whether it is possible to limit individual rights and freedoms in the name of public health safety. The article considers contradictory issues in the state policy of compulsory vaccination and its legal support. The author presents a definition of compulsory vaccination, identifies its types, describes the specifics of its national legal regulation and sanctions for the refusal to be vaccinated, and explains its social necessity and expediency as a public good.
Review on the book: Bondarchuk, I. V., Butkevich, O. V., Rudenko, A. V. et al. (2020) Rule-making process in the Republic of Crimea and Sevastopol (based on materials of 2019): a textbook for masters. Simferopol, Arial publishing house
Authors: Radko Timofey N. , Nazaykinskaya Varvara A.
Published: March 2022

The review analyzes the content of the textbook Rule-making process in the Republic of Crimea and Sevastopol, prepared by a team of authors representing not only Crimean universities that provide training in the areas 40.04.01 Jurisprudence and 38.04.04 State and municipal government, but also directly involved in the legislative process. It is emphasized that this is the third book in a series of publications based on the annual reports of the State Council of the Republic of Crimea and reports of the Legislative Assembly of the city of Sevastopol on the state of regional legislation. The authors point to a well-grounded combination of theoretical and practical foundations of rule-making activity in the constiuents of the Russian Federation under study. It is noted that the cycle of publications based on legal monitoring of the legislative activities of the State Council of the Republic of Crimea and the Legislative Assembly of the city of Sevastopol is successfully combined with a theoretical review of issues related to the preparation of draft laws. These facts make the manual a useful source not only for undergraduate students, but also for all specialists working in the field of regulatory activity.
Transformation of several issues of exemption from obligations under cross-border and domestic contracts due to COVID-19: analysis of judicial practice
Authors: Alimova Yana O.
Published: March 2022

The COVID-19 pandemic has completely changed the entire life of the society. Today, the world witnesses the third wave of the COVID-19 pandemic. This is evidenced by the steadily increasing number of new cases of contamination. Despite the difficult situation, every day merchants continue to conclude cross-border and domestic contracts. Therefore, the issue of exemption from obligations due to the onset of the consequences of the COVID-19 pandemic is relevant and requires detailed consideration. We propose to analyze two concepts, namely, force majeure and a significant change in circumstances (hardship), in order to analyze the judicial practice (case law) developing at the international level in different countries and at the national level in the Russian Federation. The article analyzes international acts of both state and non-state regulation, examines the approaches of foreign state courts to the issues of exemption of counterparties from fulfilling obligations due to the onset of the consequences of the COVID-19 pandemic and practice of Russian courts. The study was conducted using general scientific and special methods of cognition: logical, systemic-structural, methods of generalization, synthesis, induction, and deduction. Certain substantive conclusions are made based on the comparative research method. Analysis of the Russian judicial practice concerning the application of the concept of exemption from the fulfillment of obligations shows that, unfortunately, Russian courts apply dual practice regarding recognition of a particular circumstance as a basis for releasing a counterparty from liability. This is explained by the fact that the principle of pacta sunt servanda (contracts must be executed) continues to be of decisive importance in international practice. With regard to the second concept application, namely, a significant change in circumstances, we note a positive practice of Russian courts. Currently, the Russian courts recognize the circumstance that affected performance under the contract due to the onset of coronavirus infection or consequences of the COVID-19 as a significant change in circumstances.
IDENTIFIKASI BEBAN KERJA UNTUK PENINGKATAN PRODUKTIFITAS DIVISI HELP DESK DENGAN METODE WORK SAMPLING
Authors: Kartika Hayu , Ambarita Rifka , Bakti Candra Setia
Published: March 2022

Penelitian dan pengamatan ini dilakukan di perusahaan jasa konstruksi dan perawatan menara telekomunikasi, untuk mengontrol setiap menara telekomunikasi dibentuk suatu divisi baru yaitu divisi Help Desk. Namun, setelah dibentuk divisi tersebut terdapat beberapa evaluasi dari manajemen, karyawan pada divisi Help Desk mengalami kelelahan, sakit dan sering izin tidak bekerja. Oleh sebab itu, penelitian ini dimaksudkan untuk menghitung beban kerja dan produktifitas dari karyawan divisi Help Desk. Untuk mencari solusi tersebut dilakukan proses identifikasi beban kerja setiap karyawan dengan menggunakan metode Work Sampling. Dari hasil yang di dapat beban kerja dari divisi Help Desk rata-rata sebesar 102,730% untuk mengurangi beban kerja karyawan tersebut divisi help desk harus menambahkan 1 orang karyawan sehingga beban kerja dapat ditekan rata-rata menjadi 77,05%. Dengan penambahan karyawan ini diharapkan dapat mencapai performa pelayanan yang lebih baik
PERAN FILSAFAT ILMU PADA BIG DATA
Authors: Bu'ulolo Efori , Zarlis Muhammad , Nasution Zulkifli
Published: March 2022

Peran filsafat ilmu pada big data tidak terlepas dari manusia yang berfilsafat. Sebagai makhlud hidup yang sempurna, manusia mempunyai akal dan pikirin. Akal dan pikiran tersebut dipergunakan untuk mencari kehidupan, bertahan hidup dan mencari solusi atas permasalahan yang dihadapinya. Logika dan ciri filsafat yang mendasari perkembangan kehidupan manusia, termasuk peralatan yang digunakan. Peralatan tersebut terus berkembang hingga saat ini dan sudah berbasis teknologi. Teknologi tidak terlepas dari ilmu komputer, dimana teknologi dapat bekerja atau berfungsi karena inputan dari komputer. Saat ini semua kegiatan manusia sudah menggunakan komputer sehingga menghasilkan ukuran data yang berukuran besar yang disebut dengan big data. Pengetahuan yang dihasilkan dari big data melalui proses data science, digunakan sebagai input pada kecerdasan buatan. Kecerdasan buatan bekerja sesuai dengan pengetahuan yang diterimanya dan dapat dimanfaatkan pada berbagai bidang diantaranya yaitu bisnis, pajak, perbankan, kesehatan,  IoT, pemerintahan dan lain sebagainya
EVALUASI STRATEGI KOMUNIKASI KEMENTERIAN DESA-PDTT DALAM MEMBANGUN AWARENESS PROGRAM INOVASI DESA TAHUN 2018-2019 (STUDI KASUS DI KABUPATEN SUKABUMI, JAWA BARAT)
Authors: WIBOWO PRASETYO EDHO
Published: March 2022

Villages are an important part of community development that cannot be separated. The importance of village development has received the attention of various experts in rural planning. The existence of the village is the forerunner to the development of a country that dares to build from the smallest things in the government structure. The village innovation program is designed to encourage and facilitate the strengthening of village capacity that is oriented towards meeting the achievement of the targets of the mediumterm development plan (RPJMN). This research refers to the communication strategy which is the best combination of several communication elements starting from the communicator and message content. The method that the researcher uses in this discussion is a case study in Girimukti Village, Ciemas District, Sukabumi Regency, West Java with a qualitative approach. The results of the study indicate that it can be concluded that the communication strategy carried out by the Ministry of Villages-PDTT towards the Village Innovation Program focuses on two communication strategies. Namely direct and indirect communication. In direct communication, the Ministry of Villages-PDTT chooses mass media, while indirect communication focuses on structural communication strategies.
KETUPAT EID TRADITION OF THE NORTH COAST OF JAVA AS AN ALTERNATIVE MATHEMATICS LEARNING MEDIA
Authors: Utami Wikan Budi , Aulia Fikri , Permatasari Dian , Taqiyuddin Muhammad , Widodo Sri Adi
Published: March 2022

Learning mathematics requires real situations that students often face. Tradition as local wisdom from the surrounding community can be used for learning mathematics so that students can reach the context of abstract mathematics. In this article, the researcher explains how teachers can take advantage of local culture and traditions in the form of Ketupat Eid on the north coast of Java to be used in learning mathematics. This research was conducted on the northern coast of Java, where every seventh day after Eid Mubarak, the area performs the Ketupat Eid tradition. Researchers tried to connect some foods that only exist in the Ketupat Eid tradition in the form of Ketupat and Lepet with mathematics in school. The results showed that diamonds could be used for rhombuses, prisms, and beams, and Lepet can be used as a tube context in geometry learning.
Utilization of Corn (Zea Mays) wastes in Bioethanol production by Separate Hydrolysis and Fermentation
Authors: Osei Janet Appiah
Published: March 2022

The study investigates the feasibility of producing bioethanol from corn (Zea mays) wastes. Corn cobs, husks and grains were collected from Githurai market and analysis was done in the Kenyatta university laboratory. Wastes were physically pre-treated to increase their surface area for enzymatic reactions. Separate Hydrolysis and Fermentation were carried out by using Aspergillus niger for enzymatic hydrolysis and Saccharomyces cerevisiae yeast for fermentation at different incubation temperatures (28oC, 30oC, 32oC) and times (24, 48, 72 and 96 hours). Fermentation was carried out in 150 ml cotton- plugged conical flasks containing 100 ml sample hydrolysates inoculated with 2 ml cultured yeast suspension. Ethanol concentration was determined by potassium dichromate oxidation method after each incubation time and expressed as % v/v whilst ethanol yield (l/kg) was derived from the ethanol concentration divided by the quantity of substrates used.  Maximum yields of 1.84 l/kg, 1.76 l/kg and 2.05 l/kg were obtained from 50 g of pre-treated corn cobs, corn husks and corn grains respectively. The optimum temperature for maximum ethanol yield in all corn substrates was 30oC whilst incubation time 96 hours, 48 hours and 24 hours were optimum for ethanol production in corn cobs, corn husks and corn grains respectively. Results show that bioethanol can easily be produced from corn wastes and is recommended that they are used wisely for energy generation specifically bioethanol to add value to them rather than landfilling.
DIGITALISASI DAN IMPLEMENTASI 5S (SEIRI, SEISO, SEITON, SEIKETSU, SHITSUKE) PADA UMKM JENANG ALIYA KUDUS
Authors: Supriyanto Agus , Lukas Ahmad , N.A Alfiyatun Nida' , Najiha Nuhayatun , Alfisyahr Layli Noor , Hikmah Nurul , Sutrisno Sutrisno , Aziz M. Abdul , Khoiriyah Nur
Published: March 2022

The purpose of the service program being implemented is to provide training on the use of information technology to market products from UMKM Jenang Aliya Kudus. Marketing that is carried out is still conventional and the absence of social media from products from MSME Jenang Aliya makes these products not widely known by netizens. The result of the implementation of this service program is that MSME actors know the importance of using digital technology to introduce and market their products to the wider community. Because Kudus, besides being known as the city of kretek, is also known for its jenang souvenirs. This service program is carried out by introducing products to netizens through creating addresses on a google map, creating social media accounts starting from Facebook, Twitter and Instagram. Meanwhile, the implementation of 5S (Seiri, Seiso, Seiton, Seiketsu, Shitsuke) is carried out so that the work place and environment become tidier, cleaner, and organized according to their classification.
PENGARUH BIMBINGAN ISLAMI TERHADAP INFERIORITY FEELING ANAK PINGGIRAN DI LSM PEMBERDAYAAN PEREMPUAN DAN ANAK PINGGIRAN (PPAP) SEROJA
Authors: Ristiana Evi , Fadilah Galih Fajar
Published: March 2022

Islamic guidance based on the Al-Qur'an and Hadith can make a person control inferiority feelings in order to accept himself completely, have confidence in his abilities, and be confident in the work he does. Islamic guidance makes humans behave healthy and can control their deviant behavior. Because with religion and faith make a better person. The purpose of this devotion is to find out whether Islamic guidance has an effect on the inferiority feeling of marginal children in the NGO PPAP Seroja Jebres Surakarta. The population in this study were the peripheral children in the PPAP Seroja Jebres NGO Surakarta. The sample in this study amounted to 15 people with random sampling technique. The results show that there is a significant influence between Islamic guidance variables and inferiority feeling. The contribution of the influence of Islamic guidance on inferiority feeling is quite large
PEMBERDAYAAN PEREMPUAN MELALUI PENDIRIAN KELOMPOK USAHA SERAI PITAY BERBASIS SOCIALPRENEUR GUNA MENINGKATKAN KESEJAHTERAAN MASYARAKAT KUPANG NTT
Authors: Prasetiyawan Arian Agung
Published: March 2022

KKN Nusantara 3T (Disadvantaged, Foremost, and Outermost) is the implementation of the Collective Labor Agreement between the Directorate General of Islamic Education of the Ministry of Religion and the Directorate General of Disadvantaged Areas of the Ministry of Villages Development of Disadvantaged Areas and Transmigration concerning Collaboration in the Development of a Higher Education Model Building a Village through Community Service which is signed August 7, 2019. The location of the implementation of the Community Service Program is classified into 2 Zones: the East Nusa Tenggara Province Zone with the theme "Peace Building" and the Maluku Province Zone with the theme "Trauma Healing". The method used is the ABCD (Asset Based Community driven Development) approach. The dedication carried out by the 3 Kupang Zone groups "Empowering Women through the Establishment of a Socialpreneur-Based Serai Pitay Business Group to Improve Welfare in Pitay Village, Sulamu District, Kupang, East Nusa Tenggara". In accordance with the analytical knife used, namely the ABCD (Asset Based Community driven Development) approach method, the program has gone through a series of stages starting from identifying natural resource assets in the form of abundant lemongrass plants, socialization and demonstration of making, FGD, formation of lemongrass business groups, making SOPs, assisting group management, and launching Serai Pitay Juice as a typical product of Pitay Village. The hope is that the group will continue to produce and develop products even though the KKN Nusantara 3T is over. In addition, we hope that women's empowerment and community welfare development in Pitay Village, Sulamu District can be realized.
UPAYA PENGUATAN KAPABILITAS MASYARAKAT DALAM PENGENALAN PERILAKU HIDUP BERSIH DAN SEHAT (PHBS) DI ERA NEW NORMAL
Authors: Sucipto Sucipto , Istiqomah Siti
Published: March 2022

The lack of socialization of Covid-19 in remote villages has caused the public to pay less attention to the Coronavirus. Through community service and research activities conducted by students using direct observation methods in the community, interviews and documentation and tracing and analyzing problems faced by the village, especially the problem of implementing health protocols in the new normal era. Therefore, the service that was carried out at Dukuh Sulicilik, Jebugan Village, North Klaten led to education about Covid-19, the implementation of health protocols in the New Normal era, as well as the introduction of the community to the culture of Clean and Healthy Living Behavior (PHBS) to create a more life. healthy, clean and high quality.
STRATEGI PROMOSI DAN INOVASI PRODUK UPAYA MEMULIHKAN DAN MENINGKATKAN UMKM MASYARAKAT DI DESA KOPEN
Authors: Widiyastuti Anissa , Tanfidiyah Nur
Published: March 2022

This service activity focuses on Micro, Small and Medium Enterprises (MSMEs) in Kopen Village, Ngadirejo Village, Kartasura District so that what will be discussed in depth is economic activity in the form of production. The purpose of this service is to carry out promotional strategies through social media and product innovation to prevent boredom and encourage consumer appeal. While the service method used is Participatory Action Research. This method has several stages that must be carried out, including: 1) assessing needs, 2) designing needs, 3) implementing planning, and 4) evaluating the activities that have been carried out. While the results of these activities, the community really appreciates it. Because promotional strategy activities and product innovation provide new insights, especially on the use of technology to promote their merchandise more easily anywhere and anytime. Most of the participants asked to join the culinary group on social media, one of which was Facebook. In addition, product innovation makes merchandise more attractive and different. This was proven after several days of UMKM participants posting their products on social media, some of the participants got responses from the public starting from asking for merchandise. Based on the statements and results made, it is sufficient to confirm that the existence of promotional strategies and product innovation activities helps restore and improve community businesses in Kopen village.
PEMBINAAN STRATEGI PEMASARAN PRODUK PEPAYA CRISPY DI MEDIA SOSIAL PADA MASA PANDEMI
Authors: Abdullah Anisatul Maghfiroh , Nisa Luthfatun
Published: March 2022

Era digitalisasi ini sudah banyak kemudahan dalam pemasaran sebuah produk. Ketika masyarakat sudah memahami bagaimana caranya maka sangat bermanfaat bagi masyarakat. Pemasaran melalui sosial media whatsapp dan Instagram sangat mudah dari pada mendaftar di e-commerceÂ seperti shoppe, tokopedia, lazada, dan lain-lain. Apalagi saat ini dalam masa pandemi, menjadikan masyarkat lebih hidup secara terbatas. Karena pemasaran melalui e-commerceÂ tersebut butuh syarat tertentu lain halnya dengan Whatsapp dan Instagram. Dua media sosial tersebut hanya butuh kontak customer atau followers. Produk pepaya crispy sebelumnya dijual ditoko-toko kecil dan jangkauan konsumen lebih kecil, dan hanya dikenal oleh masyarakat yang hanya berdekatan dengan toko tersebut, akan tetapi dengan adanya pendampingan pelatihan pemasaran di media sosial seperti ini maka omset akan bertambah dan lebih ringan. Karena masyarakat di masa pandemi ini akan lebih beraktivitas secara terbatas. Pelatihan dan pendampingan brandingÂ dilakukan di rumah warga yang membuat hasil produksi, dari hasil pendampingan ini menunjukkan kemajuan dalam pemasarannya. Dalam meningkatkan omset penjualan melalui pemasaran di media sosial.
VIDEO MATH FEST: SARANA MENINGKATKAN LITERASI DIGITAL OLEH WALI SISWA JENJANG SEKOLAH DASAR
Authors: Adibah Fanny , Sari Ira Wulan
Published: March 2022

Kekacauan yang terjadi akibat pandemi Covid 19 memaksa berbagai aktivitas dilakukan secara daring, termasuk proses pembelajaran bagi anak-anak usia sekolah. Sistem belajar dengan konsep jarak jauh di tingkat TK, SD, SMP, SMA hingga Perguruan Tinggi ini dilakukan dalam rangka memutus rantai penyebaran Covid-19 di Indonesia. Penggunaan gawai oleh anak-anak yang sebelumnya dilarang atau dibatasi, sekarang justru menjadi kebutuhan sehari-hari. Kegiatan pengabdian ini bertujuan untuk meningkatkan kemampuan literasi digital wali siswa agar dapat menanamkan literasi digital pada anggota keluarganya sehingga lebih banyak manfaat teknologi digital yang diraih dan meminimalkan dampak negatif. Kegiatan pengabdian ini berbentuk penyelenggaraan lomba/festival dengan konten video belajar matematika dari rumah bersama orang tua (pendamping) yang asyik dan menyenangkan dengan namaVideo Math Fest. Hasil kegiatan pengabdian dianalisis secara deskriptif kualitatif dan diperoleh kesimpulan bahwa analisis rata-rata literasi digital wali siswa dilihat dari penilaian produk video yang mereka buat berada pada ketegori â€œtinggiâ€ diikuti dengan rata-rata hasil respons positif di setiap aspek kegiatan.
Universal temperature dependence of nutritional demands in ectotherms
Authors: Laspoumaderes Cecilia , Meunier Cédric , Magnin Amaru , Berlinghof Johanna , Elser Jim , Balseiro Esteban , Torres Gabriela , Modenutti Beatriz , Tremblay Nelly , Boersma Maarten
Published: March 2022

In light of ongoing climate change, it is increasingly important to know
how nutritional requirements of ectotherms are affected by changing
temperatures. Here, we analyse the wide thermal response of phosphorus
(P) requirements via elemental gross growth efficiencies of Carbon (C)
and P, and the Threshold Elemental Ratios in different aquatic
invertebrate ectotherms such as the freshwater model species Daphnia
magna, the marine copepod Acartia tonsa, the marine heterotrophic
dinoflagellate Oxyrrhis marina, and larvae of two populations of the
marine crab Carcinus maenas. We show that they all share a non-linear
cubic thermal response of nutrient requirements. Phosphorus requirements
decrease from low to intermediate temperatures, increase at higher
temperatures, and decrease again when temperature is excessive. This
universality in the thermal response of nutrient requirements is of
great importance if we aim to understand or even predict how ectotherm
communities will react to global warming and nutrient-driven
eutrophication.
Neurocognitive Outcomes of Children with Osteosarcoma Treated with High-dose Intravenous Methotrexate
Authors: Shima Haruko , Sato Satomi , Takimoto Tetsuya , Sakai Michiko , Hashida Noriko , Isshiki Kyohei , Shimada Hiroyuki
Published: March 2022

Methotrexate (MTX) has been shown to impair neurocognitive outcomes.
Because the cumulative dose of MTX used in the standard treatment of
osteosarcoma is higher compared to the treatment of other childhood
cancers, we analyzed the neurocognitive performance among 12 survivors
of childhood osteosarcoma exposed to high-dose MTX at our institution.
Prospective longitudinal evaluations of neurocognitive functioning using
the Japanese Wechsler Intelligence Scale for Children-4th Edition were
performed. As a result, we observed age-appropriate development of
neurocognitive performance among osteosarcoma survivors. In conclusion,
cognitive development was not adversely affected in this cohort of
childhood osteosarcoma survivors treated with HD-MTX.
Profile of adverse drug events in depressed inpatients in China and associated risk factors: a retrospective review using the Global Trigger Tool
Authors: Tian Xiaojiang , Yao Yao , Wang Xiaoli , Wang Hong , Li Wei , Chen Lin , Diao Junlin , Jia Yuntao
Published: March 2022

Objective: The aim of the study was to evaluate the feasibility and
potential of the Global Trigger Tool (GTT) for identifying the adverse
drug events (ADEs) in patients with depression. Methods: In this study,
the trigger items for antidepressants were developed base on the
‘Institute for Healthcare Improvement (IHI) GTT for Measuring Adverse
Events’ . Trigger detection of the medical records was carried out in
200 patients diagnosed with depression in a specialized hospital. Each
medical record with the presence of any of the triggers was reviewed by
two researchers respectively to determine whether it was an ADE, if so,
ADE should be classified in severity, and involved system and primary
suspected drug were identified. Logistic regression was performed to
investigate risk factors associated with ADEs, and ADE detection rate
and positive predictive value (PPV) were calculated to evaluate the
sensitivity and specificity of the triggers. Results: Triggers were
detected for 162 times in 159 cases (79.5%), and 69 ADEs in 61 patients
were identified by record reviewing. the PPV of the trigger tool was
42.59%. 79.7% were classified as category E, and 20.30% category F.
ADEs were most likely to involve metabolic system (34.78%), manifested
as hypokalemia, pathoglycemia and hypercholesterolemia. venlafaxine was
most likely to cause AEs (32.56%), followed by paroxetine (22.09%).
Risk factors for ADEs included the number of administrated
antidepressants (p=0.008) and the number of concomitant drugs (p=0.014).
Conclusion: The GTT is a feasible and effective tool for detecting ADEs
of antidepressants for inpatients.
Crioconservación de semen de dorada (Brycon sinuensis) con diferentes crioprotectores a dos porcentajes de inclusión
Authors: Carmona-Calderón Jorge , Espinosa-Araújo José , Atencio-García Víctor , Díaz-Hernández Omar
Published: March 2022

La criopreservación permite la conservación de recursos genéticos de peces en peligro de extinción y mejora procesos reproductivos en cautiverio. El objetivo del estudio fue evaluar semen de dorada con tres crioprotectores internos a dos porcentajes de inclusión. Se utilizaron reproductores en fase espermiación (n=12), inducidos con 5 mg de extracto hipofisario de carpa/Kg. Seis horas después el semen fresco (SF) fue colectado y diluido en soluciones crioprotectores compuesta por glucosa 6%, yema de huevo 12% y los crioprotectores dimetilsulfóxido (DMSO), dimetilacetamida (DMA) y etilenglicol (EG) a porcentajes de inclusión de 5 y 10%; luego empacado en pajillas de 0.5 mL y congelado con vapores de nitrógeno. El semen fue descongelado quince días después en baño serológico. La calidad del SF, precongelado (SP) y descongelado (SD) fue evaluada con el software SCA® (Sperm Class Analyzer). Fue evaluada la movilidad total (Mt), tipos de movilidad, velocidades, progresividad total y concentración espermática. En SD se estimaron los daños en membrana espermática (D-Mem), mitocondria (D-Mit) y fragmentación de DNA (F-DNA) mediante citometría de flujo. La Mt del SF fue de 97.0±7.0%, en SP fue de 82.5±17.9% y en SD de 45.4±13.6%; siendo mayor cuando fue tratado con DMSO10% (p<0.05). En SD los D-Mem oscilaron de 62.1±18.8% (DMA 5%) y 49.89.8% (DMSO 5%); los D-Mit de 59.4±14.8% (DMA5%) a 83.4±4.2% (DMSO10%) y F-DNA entre 9.5±14.0% (EG10%) y 1.6±0.2% (DMA10%) (p>0.05). Los resultados obtenidos permiten inferir que los crioprotectores evaluados incluidos a 5 y 10%, son una alternativa viable para la crioconservación de semen de dorada.
The First National Hygiene Exposition in Belgrade in 1933
Authors: Vukotic-Lazar Marta , Roter-Blagojevic Mirjana
Published: March 2022

The paper is about the First National Hygiene Exposition in Belgrade in 1933. It was one of the most significant events and an important part of the cultural policy in the Kingdom of Yugoslavia at that time. It was also the last one in a series of great events under the high patronage of King Aleksandar I Karadjordjevic. In order to make research in the novelties the exposition introduced, the thus far unpublished archival material has been studied along with the situation drawings of the complex and the restaurant, photo documentation and the exposition presentation in the newspapers of the time, as well as the published material. The aim of the paper is to emphasize the significance of the exposition, its dominant health and education concept with regard to social improvements for the benefit of the general public, all in the context of the period and under conditions it was organized. The paper also aims at presenting a comprehensive view of the exposition impact on the history of the Serbian and Yugoslav medicine, as well as the modernization of the society on the whole. The paper also includes the hitherto unpublished archival material, plans, photographs, brochures? front pages and so on.
Covid-19's impact on radiotherapy in the Republic of Srpska
Authors: Kolarevic Goran , Jaros Drazan , Pavicar Bojan , Marosevic Goran
Published: March 2022

Background/Aim. Coronavirus disease 2019 (COVID-19) significantly affects patients with any type of chronic disease, especially the ones with neoplasm. The aim of this study was to investigate the impact of the COVID-19 pandemic on the weekly number of external beam (EB) radiotherapy (RT) (EBRT) fractions and monthly brachytherapy (BT) applications without intentional hypofractionation. We also investigated how the pandemic affected the number of EBRT patients younger or older than 70 years. Methods. The Affidea Radiotherapy Center, Banja Luka (BL RT Center), provides RT to the population (1.15 million) of the Republic of Srpska (Bosnia and Herzegovina). We analyzed the period of 14 months before the onset and the same period during COVID-19. Results. The average weekly number of EBRT fractions from January 2019 to the end of February 2020 was 680.5 [standard deviation (SD) 67.4], and from March 2020 to the end of April 2021, it was 617.1 (SD 96.4). During April 2020, the weekly number of the EBRT de-creased by 67.9% compared to the same period in 2019, while in March 2021, it fell by 42.4%. Paired samples t-test showed that the occurrence of the COVID-19 pandemic had a statistically significant effect [t(60) = 4.627, p < 0.05] on the reduction in the number of weekly EBRT fractions in the BL RT Center. When comparing number of EBRT patients over 70 years old to those fewer than 70 years old, the decrease was 16.3% vs. 1.6%, respectively. The Wilcoxon signed-rank test revealed that the COVID-19 pandemic had a statistically significant effect (Z = -2.42, p = 0.016) on reducing the number of monthly BT applications. Conclusion. A statistically significant decline in EBRT and BT was observed in BL RT Center for the first fourteen months of the pandemic. The "waves" of the pandemic "closed" the medical wards needed for the diagnosis and therapy of oncology patients and converted them into COVID-19 wards. Therefore, some oncology patients who would have had an indication for RT never received
Association of Type 2 Diabetes Risk Perception With Interest in Diabetes Prevention Strategies Among Women With a History of Gestational Diabetes
Authors: Vu Amanda , Turk Norman , Duru O. Kenrik , Mangione Carol M. , Panchal Hemali , Amaya Sarah , Castellon-Lopez Yelba , Norris Keith , Moin Tannaz
Published: March 2022

Objectives

The aims of this study were to identify predictors of perception of type 2 diabetes risk in women with a history of gestational diabetes mellitus (GDM) and to determine factors associated with interest in evidence-based strategies for type 2 diabetes prevention.

Research Design and Methods

We surveyed women with a history of GDM who had not progressed to type 2 diabetes from a large academic medical center. We used multivariate logistic regression to assess predictors of high levels of perception of type 2 diabetes risk. We also tested associations between risk perception and interest in a lifestyle change program and/or metformin therapy.

Results

In our diverse sample of 264 women, 28% were unaware that GDM is a risk factor for incident type 2 diabetes after pregnancy, and 48% believed their personal risk of type 2 diabetes was low. In multivariate analyses, family history of diabetes (odds ratio [OR] 2.2, 95% CI 1.2–4.4) and knowledge of GDM as a risk factor for incident type 2 diabetes (OR 4.5, 95% CI 2.1–9.8) were significant predictors of greater perception of type 2 diabetes risk. Women with higher risk perception were more likely to express interest in a lifestyle change program compared with women with lower risk perception (OR 2.4, 95% CI 1.3–4.5).

Conclusion

Although some women are aware that GDM is a risk factor for incident type 2 diabetes, many still perceive their own risk of developing type 2 diabetes as low. Higher risk perception predicted interest in an evidence-based diabetes prevention program, highlighting the importance of personalized risk assessment and communication about risk for women who have had GDM.
ENTRANCE GATES OF DEFENSE MONASTERIES WESTERN UKRAINE
Authors: Chen Lesya
Published: March 2022

The article examines the main entrance gates of the defensive monasteries that have survived to the present day in Western Ukraine. Considered and analyzed architectural and artistic and compositional solution defensive monastery gates - structural elements important defensive zone fortified monasteries.
WOOD IN WORKS OF ART AND ARCHITECTURE, HISTORY OF USE AND PROBLEMS OF CARE
Authors: Chornyi Maksym
Published: March 2022

Wood is a material used to create works of art, architecture and has been known to people for thousands of years. In Ukraine there is a huge number of outstanding works of architectural, art, decorative, sacred, industrial and utilitarian nature. Significant efforts are being made by conservation and museum workers to preserve and care for such works. The article provides information about the history of using wood to create works of art and architecture. The complex of art history, technological, nature protection and conservation-restoration information is generalized and the holistic understanding of the important role research and preservation of works, made with the wood use is given. The history of the woodworking industry in Ukraine was studied by S. Hensiruk, O. Furdychko, V. Bondar, and the specifics of artistic woodworking craft were analyzed by B. Suliak, M. Serhieieva. Peculiarities of Ukrainian wooden architecture were studied Y. Taras, L. Prybieha, Y. Ivashko, H. Shevtsova. Important information on the experience of preserving the cultural heritage of Ukraine can be found in the publication from O. Rybchynsky. This article analyzes the areas of wood application as a basis for the manufacture of art works, and architectural construction. The specifics of the use wooden in sacred architecture, art, decorative and applied arts of Ukraine are outlined. The types made of wooden art works are determined and their role in the Ukrainian culture is established. It is substantiated that the preservation of valuable art works is a very important task for conservation science and society in general. The author reveals the main problems of preservation and the reason for the destruction of wooden art works, and to implement the correct methods of preserving wooden objects, an interdisciplinary, synthetic approach is needed. All works of wood are constantly under the destructive influence of many factors, and the article identifies modern ways to overcome the problem of destruction wooden art works and basic care for them.
TOWN OF DOBROMIL AND ITS CASTLES: AN ATTEMPT OF RECONSTRUCTION THE PLANNING STRUCTURE FOR THE 17TH CENTURY
Authors: Bevz Mykola
Published: March 2022

In this article we try to reconstruct the planning structures of town of Dobromil in Rus` (Rythenia) province of Kingdom of Poland at the time of 17th century. Dobromil (ukr. Dobromyl) was the main private city of Herburt family in the valley of the river Strvyazh in the Sambir district. We perform attempts of a hypothetical planning reconstruction of this city on the basis of an analysis of a number of historical maps of the late 18th and 19th centuries. The city of Dobromyl also has the peculiarity that Herburts founded two castles here – the High Castle at a certain distance from the city and the Low Castle near the midtown. Jan Herburt from Felshtyn became famous for founding a printing house in Dobromyl, where significant written historical works were first printed in 1611-1616 – a chronicle of Poland by Jan Długosz and letters by Orżechowski. An important material for the hypothetical reconstruction of city layouts and city fortifications was the hand-drawn map by d'Otto from 1772, the map by F. von Mieg from the 1779-1781, cadastral maps from the 1852, and 1853, maps from 1860-1864 of the Second cartographic survey of Galicia.
MAKSIM KESANTUNAN FALIA PADA SISTEM PERTANIAN MASYARAKAT MUNA: KAJIAN PRAGMATIK
Authors: Abdin Non
Published: March 2022

Abstrak: Penelitian ini bertujuan untuk menggali maksim kesantunan falia pada sistem pertanian masyarakat muna. Metode yang digunakan yaitu deskriptif kualitatif. Hasil penelitian ini menunjukkan adanya prinsip maksim kesantunan falia pada sistem pertanian masyarakat muna, serta adanya pelanggaran maksim kesantuanan. Kesimpulan yaitu Falia yang diterapkan dalam sistem pertanian masih tetap dipertahankan sampai sekarang sebab, orang tua selalu memberitahu dan menyampaikan falia yang berdampak negatif apabila melanggar falia. Falia mengandung makna yang berisi ungkapan nasehat yang berupa pantangan dan larangan agar kita tidak salah langkah, dan pekerjaan yang kita lakukan terkontrol dengan baik.Kata Kunci: falia, sistem pertanian, pragmatik Abstract: This research aim to explore the maxims of falia politeness in the agricultural system of the muna. The method used is descriptive qualitative. The results of this study indicate the existence of the maxims of falia modesty in the agricultural system of the muna, as well as a violation of the maxims of politeness. The conclusion is that Falia which is applied in the agricultural system is still maintained until now because parents always tell and convey falia which has a negative impact if it violates falia. Falia contains a meaning that contains an expression of advice in the form of taboos and prohibitions so that we don't take wrong steps, and the work we do is well controlled.Keyword: falia, farming system, pragmatic
CITRA PEREMPUAN PENARI DALAM NOVEL RDP KARYA AHMAD TOHARI DAN PDS KARYA YUDHISTIRA ANM MASSARDI
Authors: Imtinan Rifa Rasyidah , Kadafi Tito Tri
Published: March 2022

Abstrak: Citra Perempuan Penari dalam Novel RDP Karya Ahmad Tohari dan PDS Karya Yudhistira ANM Massardi. Penelitian ini bertujuan untuk mengetahui bentuk citraan terhadap perempuan yang berprofesi penari dalam novel Ronggeng Dukuh Paruk karya Ahmad Tohari dan Penari dari Serdang Karya Yudhistira ANM Massardi. Adanya bentuk tokoh yang sama menjadi bahan perbandingan bagaimana sebuah tokoh perempuan ‘penari’ digambarkan dalam sebuah karya sastra. Teori yang digunakan merupakan teori kritik sastra feminis. Penelitian ini menggunakan pendekatan deskriptif-kualitatif dengan metode sastra perbandingan. Kedua novel yang memiliki kurun waktu penerbitan yang berbeda yakni RDP rentang waktu 1940-1960-an dengan PDS yang berlatar waktu tahun 2013, perbedaan tersebut nyatanya tidak memberikan banyak pengaruh perubahan terhadap stereotip yang diberikan kepada tokoh penari Srintil dalam RDP dan Ayu Chaya (PDS). Kata Kunci: Citra Perempuan, Kritik Sastra Feminis, Penari, Novel, SastraAbstract:  The Image of Women Dancer in Novel RDP by Ahmad Tohari and PDS by Yudhistira ANM Massardi. This study aims to determine the image of women who are dancers in the novel Ronggeng Dukuh Paruk by Ahmad Tohari and Penari dari Serdang by Yudhistira ANM Massardi. The existence of the same character form is being comparison material to know how a female 'dancer' character is depicted in a literary work. The theory used is a feminist literary criticism theory. This study uses a descriptive-qualitative approach with the comparative literature method. The two novels have different publishing periods, namely the RDP from the 1940-1960s with the PDS which is set in 2013, this difference does not in fact have much of a changing effect on the stereotypes given to the dancer Srintil in RDP and Ayu Chaya (PDS).Keywords: Women Image, Feminist Literary Criticism, Dancer, Novel, Literature
Changes in phytoplankton development in Middle Caspian in 2021
Authors: Zimina T atyana Nikolaevna , Ardabyeva Alevtina Georgievna , Kotelnikov Andrey Vyacheslavovich
Published: March 2022

The research of taxonomic diversity was completed in the water area of the Middle Caspian as a whole and by sections (Makhachkala - Cape Sagyndyk, Derbent - Cape Peschany, Divichi settlement - Kenderli Bay) for 2021. During the research period 108 samples were collected and processed. As a result of the work performed 105 taxonomic units were found, which is more than the average long-term value (87), but less than the indicators of the previous year of the research (130). The diatoms were the dominant group and accounted for 50% of the total composition. Dinophyte algae were the subdominants. The basis of the ecological complex of 2021 was formed by the representatives of seaweeds. A representative of green algae Ankistrodesmus pseudomirabilis v.spiralis influenced the formation of the abundance, reaching the greatest development in the section of the city of Derbent - Cape Peschany. In the same section of the sea the maximum biomass was also noted with a predominance of a group of dinophytes. In general, in the Middle Caspian the layer of 0–25 m was the most productive. The maximum concentration of plant cells was noted at a horizon of 25–50 m in the section of the city of Makhachkala - Cape Sagyndyk. In the section of the city of Derbent - Cape Peschany it increased from the surface horizon (34.22 mg/m3) up to a layer of 25–50 m. On the section of Divichi village - Kenderli Bay the highest concentrations were noted in the 10–25 m water layer.

In 2020–2021 b-mesosaprobes T. nitzschioides, E. cordata, Fragilaria construens were the dominant indicator species. These species are not so demanding to the environment. Organisms of the α-saprobic zone were less common, which suggests that the saprobiological state of the waters of the Middle Caspian is moderately polluted
Early data on macrozoobenthos of Lake Tikshozero
Authors: Savosin Evgeniy , Savosin Denis Sergeevich , Milyanchuk Nikolay
Published: March 2022

The article presents the results of the assessment and inventory of the current state of the macrozoobenthos communities of Lake Tikshozero (Western Karelia), which belongs to the small water bodies of the White Sea basin. The reservoir is remote from settlements and industrial facilities, it is used for recreation purposes, popular for amateur and sport fishing. There are given the results of studying the species diversity of macrozoobenthos, structure of dominant species, ratio of the main taxonomic groups, their quantitative indicators. The Tikshozero ecosystem is under the influence of human economic activity; a commercial trout farm is located in its water area. The work was carried out to assess the current state of the benthic fauna of a little-studied reservoir, which is in conditions of a transitional trophic status. The lake is part of the largest lake-river system of the Kem River in the republic and can act as

a model control object for studying the level of impact on small water bodies of the European North. Data on changes in the composition of benthic communities caused by various factors can serve as indicators of the aquatic environment. To preserve the current state of the Tikshozero ecosystem and to study the dynamics of possible changes it is necessary to conduct monitoring of the water body. Widespread indices were used to assess the degree of water quality by macrozoobenthos: chironomid index K, oligochaete index (Goodnight-Whitley), Mayer index (S). In accordance with the results obtained, the reservoir is reffered to moderately polluted water bodies. It has been established that by the level of development of macrozoobenthos and its structural and functional indicators the lake belongs to

α-mesotrophic water bodies. According to the value of the Pantle–Bukk saprobity index, the water body can be attributed to the β-mesosaprobic type (moderately polluted waters)
Comparative assessment of sea water quality based on biological indicators
Authors: Soprunova Olga Borisovna , Dyakova Svetlana Aleksandrovna , Bareeva Alina Shamilevna
Published: March 2022

The assessment of the quality of sea water samples was carried out according to biological indicators - the total number of microorganisms, which react sharply to changes in their environment. To ensure control over the ecological state of the aquatic environment, it is necessary to conduct regular monitoring studies on such microbiological indicators as the total number of microorganisms. Conventional microbiological methods for determining the total number of microorganisms are laborious and require a well-equipped laboratory and qualified personnel, and such analysis usually takes 24-48 hours. For a comparative assessment of the quality of sea water samples, the number of microorganisms was recorded by traditional methods and by the express method of chemiluminescence. As traditional methods, the method of inoculation on nutrient media, counting on a fluorescent microscope and on colored membrane filters were chosen. A chemiluminescent method was chosen for the rapid assessment of water by the total microbial abundance, which makes it possible to measure the content of bacterial cells by their ATP content. It is shown that the chemiluminescent method is superior to traditional methods for determining the total bacterial contamination (TBC, one of the main indicators of the natural object quality). At the same time, the chemiluminescent reaction made it possible to significantly reduce the measurement time and speed up data processing (measurement time did not exceed 2.5 min), i.e., it became possible to quickly analyze the samples under study in the field and in mobile laboratories. Direct positive correlations between the data determined by the traditional and new methods are revealed. The results obtained in the framework of a study on the determination of the number of microorganisms by classical methods and the chemiluminescence method allow us to recommend their use for express assessment of the quality of various natural objects.