bluuebunny/crossref_metadata_2025 huggingface dataset:
Unveiling the impact of technological innovation and SMEs resilience: the moderating role of firms' social sustainability orientation
Authors: Do Hai-Ninh , Do Ngoc Bich , Nguyen Thao Kim , Nguyen Tra My
Published: September 2024

Purpose

This study investigates the impact of personal, organisational and innovation capability on technological innovation and further impacts on small and medium enterprises’ (SMEs') performance during uncertainty. Moreover, the moderator role of social sustainability orientation on the relationships of technological innovation, innovation performance and organisational resilience is also examined.

Design/methodology/approach

A quantitative approach using 524 SME responses and Smart PLS 4.0 are adopted in this research.

Findings

The results indicate a correlation between three types of capabilities with technological innovation and further conversion to organisational resilience. Additionally, social sustainability shows a negative moderating effect between innovation performance and organisational resilience. The research findings advanced the resources-based-view (RBV) by proposing three capability dimensions as platforms for SMEs' innovation success, which later generate resilience possibilities. Specifically highlighted in this study are the personal capabilities of managers, organisational capabilities and innovation capabilities in setting business objectives and resource allocation towards economic and sustainable goals during turbulence and uncertainty.

Originality/value

This study investigates the role of technological innovation and innovation on SME resilience. Notably, we deploy the social sustainability orientation as moderators towards the relationship between technological innovation, innovation performance and SMEs’ resilience. SMEs employing social sustainability orientation might negatively inhibit the translation from innovation performance to SME resilience, providing novel insights into navigating uncertainty in modern business. It has no effect on the relationship between technological innovation and its consequences.
Psychological detachment: a bibliometric investigation within the organization’s behavior domains
Authors: Shah Tanveer Ahmad , Pattusamy Murugan , Parray Zahoor Ahmad
Published: September 2024

Purpose

The purpose of this study is to offer insight into present dynamics and study diversification in the field of organizational psychology. This research study offers an organized and critical examination of the construct of psychological detachment using bibliometric analysis.

Design/methodology/approach

This study was done using the Scopus database based on studies published between 2006 and 2024. The significance of the research is evaluated by looking at the distribution volume, the trajectory of the publication, statistics techniques, extremely cited articles, journals, most frequently used keywords, research themes, subthemes clusters and thematic overview of the psychological detachment corpus created based on bibliographic coupling. Furthermore, content analysis of recent publications to identify new developments and potential gaps in the existing literature.

Findings

This research first tracked the development of this discipline’s body of literature through time and discovered a continuous rise starting in 2015. The results also highlighted crucial concepts that were studied with psychological detachment, such as work-life balance, employment outcomes, emotional exhaustion and various other demographic variables. Researchers chose to concentrate on those subtopics throughout time.

Research limitations/implications

This research relied solely on Scopus data, which, despite being the largest abstract and citation database covering articles from a wide range of fields, does not include Impact Factor or Social Science Citation Index (SSCI) data, which is one of the limitation.

Practical implications

The findings of this research study will assist organizations and practitioners in comprehending the implications of psychological detachment construct at their workplace and give them direction on how they come out from negative job-related outcomes (employee job stress, turnover intention and burnouts at their respective workplaces).

Originality/value

This study offers a diversity of study topics across the psychological detachment literature by applying a variety of bibliographical mapping techniques, making it the first of its type on the topic of psychological detachment. It also indicates promising avenues for further investigation.
Understanding sociodemographic characteristics shaping the choice of large homes: lessons from Turkish metropolises
Authors: Caliskan Bilal , Özkan Yazar Hatice Aysun , Keskin Abdulkadir
Published: September 2024

Purpose

In metropolitan areas experiencing rapid urbanization and housing production, the size of housing units emerges as a crucial factor to consider in housing policy formulation. This study aims to focus on Turkey, a developing country undergoing rapid urbanization and a construction boom in recent years, to examine households’ housing size preferences. Through a detailed analysis, this research delves into the causal relationships between income, education and housing size preferences.

Design/methodology/approach

This study uses the Family Structure Survey in Turkey 2016 data set collected nationwide by the Turkish Statistical Institute (TurkStat). To address potential endogeneity issues related to income and education levels in households’ choice of house size, an extended regression model is used. In addition, survey weights are applied to the statistical model to generalize the results of the study.

Findings

The study demonstrates that household income correlates with an increase in house size, while household education is associated with a decrease in house size. Variables such as household age, composition and vehicle ownership are found to impact the choice of house size. Particularly, one-person and couple-only households tend to prefer smaller dwellings compared to others. Lastly, the results reveal that the influence of household composition on dwelling size varies according to household age.

Originality/value

This study presents a comprehensive analysis of the determinants influencing households’ housing size preferences within the framework of a developing country context, focusing on Turkey. It specifically offers insights into the causal impact of education and income levels on housing size preferences, as well as the intricate interplay between household characteristics in shaping these preferences.
Responsible leadership and deceptive knowledge hiding: the mediating role of moral reflectiveness and the moderating role of leader-follower value congruence
Authors: He Peixu , Zhou Hanhui , Jiang Cuiling , Anand Amitabh , Zhou Qiongyao
Published: September 2024

Purpose

The key to preventing employees from engaging in deceptive knowledge hiding is fostering a responsible environment. Drawing on social cognitive theory, this study aims to explore the factors that inhibit deceptive knowledge hiding and to construct potential pathways for enhancing individual moral cognition. This study further analyzes the moderating effect of leader–follower value congruence on these relationships.

Design/methodology/approach

Using data from 341 full-time employees in various service industries in China, this study conducted path analysis, the product-of-coefficients method and bootstrapping to test the hypotheses through a three-stage, time-lagged survey.

Findings

The empirical results show that responsible leadership is negatively associated with employees’ deceptive knowledge hiding. Employee moral reflectiveness mediates this relationship, whereas leader–follower value congruence moderates the indirect effect of responsible leadership on deceptive knowledge hiding through moral reflectiveness.

Originality/value

First, this study extends field research by introducing positive leadership factors to reduce deceptive knowledge hiding, whereas prior studies focused mainly on negative leadership antecedents. Second, this study sheds light on the underlying moral cognitive mechanisms and explains how responsible leadership can prevent implicit unethical behavior. Third, it reveals how leader–follower value congruence can enhance the impact of responsible leadership on moral reflectiveness, offering novel insights into the role of value-based fit in reducing deceptive knowledge hiding.
Keep Talking and Nobody Explodes: using gamification of cognitive overload to teach leadership and psychology concepts
Authors: Whitaker Brett , Whitaker Whitney
Published: September 2024

Purpose

Keep Talking and Nobody Explodes is a puzzle-based video game that allows Leadership educators to facilitate a highly interactive and behaviorally intense experience within a traditional classroom environment. In this manuscript, we discuss appropriate use cases, curricular alignments and provide a sample lesson plan outlining one way of using the game.

Design/methodology/approach

The cooperative and team-based nature of this game provides opportunities to create interactive lessons on a variety of topics, such as communication, group dynamics, leadership, conflict strategies and cognitive load.

Findings

Our primary reflection is that this game provides a good balance between fun engagement and rigorous learning. While deploying this game in several leadership and psychology courses, students have shown excitement and enthusiasm about playing the game, especially when we have built up some anticipation for it while discussing cognitive load theory (CLT) or other content in the classes leading up to the experience.

Originality/value

The game provides a unique behavioral experience that is useful in several different educational outlets. Fundamentally, the game provides the opportunity for creating three dynamics among small groups of students: cognitive overload, intergroup stress and conflict and communication in stressful environments. Each of these three could be applicable in various courses and curriculum.
Status of and sociodemographic and psychological correlates of personality dysfunction among university students: a cross-sectional study
Authors: Hamdan Mansour Laith A. , Al Shibi Ahmad N. , Jabaiti Samir , Alrafayia Mohammad , Hamdan Mansour Ayman
Published: September 2024

Purpose

This study aims to examine the status of personality dysfunction and its sociodemographic and psychological correlates among university students in Jordan.

Design/methodology/approach

This study used a cross-sectional, descriptive-correlational design. It was conducted in Jordan targeting 440 university students using a structured format of online survey during the period January to February 2024. Academic anxiety, loneliness, personality dysfunctions and self-esteem were the used measures in this study.

Findings

Students had moderate levels of global personality dysfunction, low to moderate levels of perception of self-esteem toward themselves, moderate to high levels of academic stress and moderate levels of loneliness. The analysis showed a significant and positive association between academic year and personality dysfunction (p = 0.004). On the contrary, no significant relationship was detected between GPA and personality dysfunction (p = 0.073). Using regression analysis, the model that included all the variables was significant (F 6,439 = 8.67, p < 0.001). In this model, the analysis showed that loneliness in the relationship with family (B = 2.08, p < 0.001) and loneliness due to friendship (B = 1.20, p = 0.035) are significant risk factors for developing personality dysfunctions.

Research limitations/implications

One limitation of this study is related to the sample and the setting. The use of an online survey and convenience sampling techniques resulted in underrepresentation of the entire types of universities.

Practical implications

The research provides empirical insights into the association between personality dysfunction among university students and feelings of loneliness, which vary depending on students academic level. Additionally, academic anxiety and self-esteem were found to be associated with or predictive of personality dysfunctions among students.

Social implications

The current research enhances our understanding of the factors contributing to personality dysfunctions among university students. Connectedness to family and strong robust binding to friends served as protective against personality dysfunctions.

Originality/value

This study emphasizes the role of social relationships and psychosocial well-being in enhancing the mental well-being of university students.
The impact of e-learning on students’ performance: the mediating role of sustainable education
Authors: Al-kasasbeh Mohammed Mufaddy , Alomari Ghassan Issa , Bani Doumi Fakhri Abudl Kareem , Alzoubi Haitham M.
Published: September 2024

Purpose

The study aims to assess the impact of electronic learning (e-learning) on students' performance (SP), with an emphasis on the mediating role of sustainable education (SE) at the Sharjah Police Sciences Academy (SPSA). The urgency of this study was highlighted by the global COVID-19 pandemic that happened between 2020 and 2022, which emphasized the need for e-learning as a tangible and imperative solution.

Design/methodology/approach

The study applied a quantitative approach, targeting the 91 student population at SPSA in the winter semester of 2022/2023 who practiced the e-learning process. A comprehensive survey was implemented disseminating 91 questionnaires by Google Forms to all students. Of the total, 61 questionnaires were returned, resulting in a response rate of 67.03%.

Findings

The results revealed that e-learning predictors explained 85.4% of the variations in SP, and 46.4% of the variations in SE. The model demonstrated a strong fit and high predictive relevance. The indirect impact of e-learning on SP through SE was found to be positive and statistically significant at the 0.05 level. Consequently, the mediation effect was considered partial and statistically significant.

Practical implications

Policymakers and educators should consider findings of the study when designing educational programs and policies. Accordingly, the SPSA management could gradually focus on safeguarding a sustainable e-learning environment and improving high-tech platforms. This would involve creating a sustainable e-learning curriculum to enable students to remain informed on the best e-learning practices.

Originality/value

An empirical study is essential for exploring the optimal answers to inquiries related to e-learning, SE and their impact on SP. The finding of the current study may contribute to the existing knowledge on e-learning, SE and SP. Additionally, they may improve learning activities and provide more sustainable learning experiences, leading to enhanced learning outcomes for students
Internal Shariah audit change: an identification of specific Islamic legal maxim in Islamic banking institution
Authors: Abd Rahman Nurulhuda , Hoque Muhammad Nazmul , Osman Muhamad Rahimi , Mastuki Norazam
Published: September 2024

Purpose

This paper aims to provide insight on internal Shariah audit change process in Islamic banking institution using sociology of translationin and the identification of specific Islamic legal maxim (ILM).

Design/methodology/approach

This paper gathered findings using qualitative approach where a single case study was selected. The study began with a preliminary study to assist the selection of the case study and later two phases of interviews done at the institution selected as the case study.

Findings

This paper has provided insights into the internal Shariah audit practices change using sociology of translation that incorporated ILM as the basis to strengthen the Islamic banking operations by achieving maqasid al-Shariah (MS). The findings of this paper provide distinguished insight on internal Shariah audit change process and ILM. The significance of this study is that a new contribution through exploring the viewpoints of the perception that satisfying the minimum legal requirements of Shariah compliance may not be sufficient for proper Shariah audit in IBIs. Therefore, the existence of ILM within a change process serves as a basis for best practices to be able to achieve MS through the means (wasa’il) used in realising IBIs’ objectives.

Originality/value

The application of ILM to internal Shariah audit change process that would guide Muslim auditors to be in line with Islamic principles. This paper focuses on the application of ILM to the Shariah audit practices changes as ILM embodied ethical value to the general concept of maslahah (well-being) under MS in the period of post-COVID-19.
Exploring the significance and priority of digital product passports implementation in building renovation projects targeting circular economy
Authors: Mêda Pedro , Hjelseth Eilif , Calvetti Diego , Sousa Hipólito
Published: September 2024

Purpose

This study explores the significance and implementation priorities for Digital Product Passports (DPP) in the context of building renovation projects. It aims to reveal bottlenecks and how a data-driven workflow bridges the DPP understanding/implementation gap, facilitating the transition towards practices aligned with the EU Green Deal goals.

Design/methodology/approach

A mixed-methods embedded design was employed for a real-case study exploration. Desk research and field observations ground the two-level analysis combining project documentation, namely the Bill of Quantities (BoQ), with different criteria in digitalisation and sustainability, such as economic ratio, 3D modelling, waste management, hazards, energy performance and facility management. All results were interpreted from the DPP lens.

Findings

The analysis revealed a system for identifying building products representing a significant part of the renovation budget. About 11 priority DPPs were found. Some are crucial for both the deconstruction and construction phases, highlighting the need for an incremental and strategic approach to DPP implementation.

Research limitations/implications

The study is limited to a single case study. Constraints are minimised given the sample's archetype representativeness. The outcomes introduce the need for strategic thinking for incremental DPP implementation. Future research will explore additional criteria and cases.

Originality/value

The research has resulted in a classification framework for DPPs' significance and priority, which is provided with case results. The outcome of the framework provides views on concept alignment to make the implementation in construction more straightforward. Its practical use can be replicated in other projects, emphasizing the importance of data structure and management for the circular economy.
How do Danish humanities PhD school leaders constitute their roles? Interactions of biography, place and time
Authors: McAlpine Lynn , Gibson Andrew , Bengtsen Søren Smedegaard
Published: September 2024

Purpose

Increasingly governmental policy around PhD education has resulted in greater university oversight of programs and student experience – often through creating central PhD Schools. While student experience is well researched, the experiences of Heads of these units, who are responsible for creating student experience, have been invisible. This exploratory Danish case study begins such a conversation: its purpose to examine the perceptions of five Heads of PhD Humanities Schools, each responsible for steering institutional decisions within Danish PhD policy landscapes.

Design/methodology/approach

A qualitative approach integrated three distinct analyses: a review of Danish PhD education policies and university procedures, each university’s job specifications for the Heads of the Schools and the Heads’ views on their responsibilities.

Findings

The Heads differentiated between their own and today’s PhD student experience. They had held prior leadership roles and fully supported institutional regulations. They cared deeply for the students under their charge and were working to achieve personal goals to enhance PhD experience. Their leadership perspective was relational: enhancing individual student learning through engaging with multiple PhD actors (e.g. program leaders) – when possible at a personal level – to improve PhD practices.

Originality/value

This study contributes an expanded perspective on how PhD School Heads constitute their roles by empirically linking: macro-national policies and institutional regulations and individuals’ biographies to their support of the PhD regimes – with implications for academic leadership generally. The authors argue research into PhD School leadership is essential, as it is such individuals who create the organisational settings that students experience.
Making inroads in the Indian AI imaging market
Authors: Majra Hufrish , Krishnan Nalini
Published: September 2024

Research methodology

This case study involves interviews with radiologists of various hospitals and with company personnel. Both primary and secondary data sources have been used. The first-hand perspective from the radiologists highlighted the challenges they face concerning time and the patient load. The company personnel highlighted using machine learning for used cases to make the platform more robust and accurate. This case has been tested with MBA students.

Case overview/synopsis

An emerging health-care artificial intelligence (AI) start-up, DeepTek.AI, wants to expand its reach in the radiology market. The company intends to leverage technology to assist radiologists in diagnostics. India's health-care sector faces the challenge of needing more trained doctors and nurses to meet the ever-increasing needs of patients. This case study revolves around the radiologists' concerns about implementing the new technology and its ease of use. The features and benefits of integrating AI in diagnostics are the need of the hour, but the reliability of results needs to be ascertained for adopting it.

Complexity academic level

This case was written for marketing applications and practices, trends in marketing, marketing strategy and technology adoption in marketing courses at the post-graduate level. Consumer adoption of finance, hospitality, travel and health-care technology is vital for increasing the company's market share and growth prospects. The students will have an opportunity to understand the challenges and the opportunities.
An investigation on anisotropic soil slope stability by LS-SVM and LEM approaches
Authors: Doostvandi Ali , HajiAzizi Mohammad , Pariafsai Fatemeh
Published: September 2024

Purpose

This study aims to use regression Least-Square Support Vector Machine (LS-SVM) as a probabilistic model to determine the factor of safety (FS) and probability of failure (PF) of anisotropic soil slopes.

Design/methodology/approach

This research uses machine learning (ML) techniques to predict soil slope failure. Due to the lack of analytical solutions for measuring FS and PF, it is more convenient to use surrogate models like probabilistic modeling, which is suitable for performing repetitive calculations to compute the effect of uncertainty on the anisotropic soil slope stability. The study first uses the Limit Equilibrium Method (LEM) based on a probabilistic evaluation over the Latin Hypercube Sampling (LHS) technique for two anisotropic soil slope profiles to assess FS and PF. Then, using one of the supervised methods of ML named LS-SVM, the outcomes (FS and PF) were compared to evaluate the efficiency of the LS-SVM method in predicting the stability of such complex soil slope profiles.

Findings

This method increases the computational performance of low-probability analysis significantly. The compared results by FS-PF plots show that the proposed method is valuable for analyzing complex slopes under different probabilistic distributions. Accordingly, to obtain a precise estimate of slope stability, all layers must be included in the probabilistic modeling in the LS-SVM method.

Originality/value

Combining LS-SVM and LEM offers a unique and innovative approach to address the anisotropic behavior of soil slope stability analysis. The initiative part of this paper is to evaluate the stability of an anisotropic soil slope based on one ML method, the Least-Square Support Vector Machine (LS-SVM). The soil slope is defined as complex because there are uncertainties in the slope profile characteristics transformed to LS-SVM. Consequently, several input parameters are effective in finding FS and PF as output parameters.
Factors influencing the adoption of mobile-based AI services in Tanzanian manufacturing SMEs
Authors: Ishengoma Fredrick , John Elia
Published: September 2024

Purpose

This study aims to establish a comprehensive framework for adopting mobile-based artificial intelligence (AI) services in Tanzanian manufacturing small and medium enterprises (SMEs).

Design/methodology/approach

The methodology involved conducting a literature review and using the combination of Mobile Services Acceptance Model and Innovation Diffusion Theory (IDT) as a theoretical foundation. This synthesis delves into the current knowledge on technology adoption, organizational behavior and innovation diffusion, creating a solid conceptual basis. Expert review was used for framework validation to ensure the framework's accuracy.

Findings

This study shows that the factors influencing the adoption of mobile-based AI services in Tanzanian manufacturing SMEs include perceived usefulness, perceived ease of use, context, personal initiatives and characteristics, trust, infrastructure, cost, mobility, power distance, compatibility, observability and trialability.

Research limitations/implications

The framework provides valuable insights tailored to Tanzanian sociocultural and economic nuances. However, its generalizability is limited due to its specificity to Tanzanian manufacturing SMEs.

Practical implications

The framework outlined in this research provides SME leaders, policymakers and technology implementers with valuable guidance to make informed decisions during the adoption process.

Originality/value

This study introduces a novel lens for understanding technology adoption. This study's focus on the Tanzanian context and its nuanced examination of contributing factors add to its originality and practical significance.
Constitutive innate immune defenses in relation to urbanization and population density in an urban bird, the feral pigeon Columba livia domestica
Authors: KAMIŃSKI Maciej , CHYB Amelia , MATSON Kevin D. , MINIAS Piotr
Published: September 2024

Urbanization processes modulate the immunological challenges faced by animals. Urban habitat transformations reshape pathogen diversity and abundance, while high population density—common in urban exploiter species—promotes disease transmission. Responses to urbanization may include adaptive adjustments of constitutive innate immune defenses (e.g. complement system and natural antibodies [NAbs]), which serve as first‐line protection against infections. Here, we investigated associations of habitat urbanization and host population density with complement and NAbs in an urban bird, the feral pigeon Columba livia domestica. To do so, we employed the hemolysis–hemagglutination assay to analyze nearly 200 plasma samples collected across urbanization and pigeon population density gradients in five major cities in Poland. We found a negative association between urbanization score and hemagglutination (i.e. NAbs activity), but not hemolysis (i.e. complement activity), indicating either immunosuppression or adaptive downregulation of this immune defense in highly transformed urban landscape. Population density was not significantly related to either immune parameter, providing no evidence for density‐dependent modulation of immune defenses. At the same time, there was a negative association of hemolysis with condition (scaled mass index), suggesting resource allocation trade‐offs or contrasting effects of the urban environment on immune defenses and body condition. The results demonstrate that habitat structure can be an important factor shaping the immune defenses of the feral pigeon, although these associations were not mediated by variation in population density. Our study highlights the complexity of the links between immune defenses in wildlife and urbanization and reinforces the need for comprehensive ecoimmunological studies on urban animals.
EU water diplomacy: A tool to strengthen the EU's soft power on environmental governance
Authors: Álvarez Arcá Ignacio
Published: September 2024

This article analyses the role of the European Union (EU) as a global governance actor in a multipolar and fragmented world. It focuses on the case of European Union water diplomacy, defined as the diplomatic and strategic use of water cooperation to promote peace, security, and sustainable development. The article argues that European Union water diplomacy is a tool to enhance the EU's soft power and influence in global environmental governance. Through an analysis of the European Union's main initiatives in this field, the article illustrates how the EU seeks to build alliances with other actors, promote multilateralism and the principles of international law, and support the participation of civil society and local communities. It concludes that European Union water diplomacy is an example of EU normative and transformative leadership that can contribute to the consolidation of a more just and sustainable international order.
Exploring the antimicrobial potential of Leukocyte‐ and Platelet‐Rich Fibrin – an in vitro study
Authors: Melo‐Ferraz António , Miller Paulo , Criado Maria Begoña , Monteiro Maria Céu , Coelho Cristina
Published: September 2024

This study investigates the antimicrobial properties of leukocyte‐ and platelet‐rich fibrin (L‐PRF) against Enterococcus faecalis (ATCC 29212), Pseudomonas aeruginosa (ATCC 27853), and Candida albicans (ATCC 90028). Infections can hinder wound healing posing challenges. L‐PRF's potential for regeneration and antimicrobial action has been studied. Considering the increasing concern about antibiotic resistance, assessing the antimicrobial properties of L‐PRF provides valuable insights into its potential as a therapeutic agent in postoperative infections. Twenty volunteers were enrolled in the study, following ethical guidelines, and obtaining informed consent. Blood samples were collected and L‐PRF was prepared. Microbial suspensions were prepared, and susceptibility testing was performed using the Kirby‐Bauer agar diffusion method. The study revealed significant heterogeneity in the susceptibility to L‐PRF. All L‐PRF membrane samples exhibited antimicrobial activity against P. aeruginosa, with inhibition zones of 13 mm ± 3.85 SD. Enterococcus faecalis displayed inhibition diameter of 7.25 mm ± 5.15 SD. Candida albicans susceptibility to L‐PRF varied among samples, with both inhibitory and non‐inhibitory results. Results showed varying degrees of antimicrobial activity, particularly against P. aeruginosa, and highlight the complexity of the L‐PRF‐microorganism interaction. Further investigations are needed to elucidate the clinical implications and optimize the use of L‐PRF.
The midwifery capabilities theory: How midwives enact woman‐centered care to address systemic inequity
Authors: Naughton Simone , Baldwin Adele , Harvey Clare , Capper Tanya
Published: September 2024

Background

Healthcare for childbearing women with complex needs demands a multi‐disciplinary approach requiring transitions between care providers, paradigms, and models of care. These transitions may create disconnects between women and the maternity care “system.” Poorly managed care transitions can lead to women becoming hostage to the power struggles between healthcare organizations and the professionals working within them, further increasing the risk of poor outcomes. This paper presents the findings of a study that aimed to better understand how midwives provide woman‐centered care for women with complex needs in the real world of maternity services.

Methods

A constructivist grounded theory approach, using Clarke's situational analysis to extend critical and feminist perspectives in data analysis. Qualitative data were obtained from two sources: publicly available data, and individual interviews with providers of care (midwives) and recipients of care (women with complex pregnancies).

Results

Woman‐centered care is defined as care in which the woman is seen, heard, and known. “The midwifery capabilities theory” describes the process whereby midwives create opportunities to develop women's capabilities. Capabilities are enabled through the midwifery relationship creating space, moments in time, and equalizing power and positionality.

Conclusions

Aligning with contemporary theories surrounding the provision of midwifery care, the midwifery capabilities theory recognizes the individual health and social status of women and the rights to self‐determination. This centers care around each individual's needs, which, in addition to improving health and well‐being outcomes, contributes to improved self‐confidence, enhancing engagement through authentic professional relationships.
Broadening accessibillity and scalability of interventions for trauma‐related conditions
Authors: Hitchcock Caitlin , Fitzpatrick Skye
Published: September 2024

Objectives

Trauma‐related conditions, such as post‐traumatic stress disorder, are associated with high rates of impairment and distress. Evidence‐based interventions for many trauma‐related conditions exert robust effects on their primary outcomes. However, logistical, financial, geographic and stigma‐related barriers to accessing these interventions exist.

Methods

Innovations that overcome barriers to access and engagement and increase the scalability of interventions for trauma‐related conditions are sorely needed.

Results and Conclusions

Here, we explore the following two potential avenues towards meeting this need: changes to the delivery model, including embedding interventions in settings which are already accessed by trauma‐exposed individuals (e.g. schools, social care systems) and harnessing advancements in technology to provide truly accessible trauma‐focussed interventions.
Cardioprotective microRNAs (protectomiRs) in a pig model of acute myocardial infarction and cardioprotection by ischaemic conditioning: MiR‐450a
Authors: Nagy Regina N. , Makkos András , Baranyai Tamás , Giricz Zoltán , Szabó Márta , Kravcsenko‐Kiss Bernadett , Bereczki Zoltán , Ágg Bence , Puskás László G. , Faragó Nóra , Schulz Rainer , Gyöngyösi Mariann , Lukovic Dominika , Varga Zoltán V. , Görbe Anikó , Ferdinandy Péter
Published: September 2024

Background and Purpose

Cardioprotective miRNAs (protectomiRs) are promising therapeutic tools. Here, we aimed to identify protectomiRs in a translational porcine model of acute myocardial infarction (AMI) and to validate their cardiocytoprotective effect.

Experimental Approach

ProtectomiR candidates were selected after systematic analysis of miRNA expression changes in cardiac tissue samples from a closed‐chest AMI model in pigs subjected to sham operation, AMI and ischaemic preconditioning, postconditioning or remote preconditioning, respectively. Cross‐species orthologue protectomiR candidates were validated in simulated ischaemia–reperfusion injury (sI/R) model of isolated rat ocardiomyocytes and in human AC16 cells as well. For miR‐450a, we performed target prediction and analysed the potential mechanisms of action by GO enrichment and KEGG pathway analysis.

Key Results

Out of the 220 detected miRNAs, four were up‐regulated and 10 were down‐regulated due to all three conditionings versus AMI. MiR‐450a and miR‐451 mimics at 25 nM were protective in rat cardiomyocytes, and miR‐450a showed protection in human cardiomyocytes as well. MiR‐450a has 3987 predicted mRNA targets in pigs, 4279 in rats and 8328 in humans. Of these, 607 genes are expressed in all three species. A total of 421 common enriched GO terms were identified in all three species, whereas KEGG pathway analysis revealed 13 common pathways.

Conclusion and Implications

This is the first demonstration that miR‐450a is associated with cardioprotection by ischaemic conditioning in a clinically relevant porcine model and shows cardiocytoprotective effect in human cardiomyocytes, making it a promising drug candidate. The mechanism of action of miR‐450a involves multiple cardioprotective pathways.

LINKED ARTICLES

This article is part of a themed issue Non‐coding RNA Therapeutics. To view the other articles in this section visit http://onlinelibrary.wiley.com/doi/10.1111/bph.v182.2/issuetoc
Contribution of T‐type calcium channel isoforms to cold and mechanical sensitivity in naïve and oxaliplatin‐treated mice of both sexes
Authors: Antunes Flavia T. T. , Gandini Maria A. , Gadotti Vinicius M. , Quintão Nara Lins Meira , Santin José Roberto , Souza Ivana A. , David Laurence S. , Snutch Terrance P. , Hildebrand Michael , Zamponi Gerald W.
Published: September 2024

Background and Purpose

The chemotherapy agent oxaliplatin can give rise to oxaliplatin‐induced peripheral neuropathy (OIPN). Here, we investigated whether T‐type calcium channels (Cav3) contribute to OIPN.

Experimental Approach

We chronically treated mice with oxaliplatin and assessed pain responses and changes in expression of Cav3.2 calcium channels. We also tested the effects of T‐type channel blockers on cold sensitivity in wild‐type and Cav3.2 null mice.

Key Results

Oxaliplatin treatment led to mechanical and cold hypersensitivity in male and female mice. Mechanical hypersensitivity persisted in Cav3.2 null mice of both sexes. Intraperitoneal or intrathecal delivery of pan T‐type channel inhibitors attenuated mechanical hypersensitivity in wild‐type but not Cav3.2 null mice. Remarkably cold hypersensitivity occurred in female but not male Cav3.2 null mice even without oxaliplatin treatment. Unexpectedly, intrathecal, intraplantar or intraperitoneal delivery of T‐type channel inhibitors Z944 or TTA‐P2 transiently induced cold hypersensitivity in both male and female wild‐type mice. Acute knockdown of specific Cav3 isoforms revealed that the depletion of Cav3.1 in males and depletion of either Cav3.1 or Cav3.2 in females triggered cold hypersensitivity. Finally, reducing Cav3.2 expression by disrupting the interactions between Cav3.2 and the deubiquitinase USP5 with the small organic molecule II‐2 reversed oxaliplatin‐induced mechanical and cold hypersensitivity and importantly did not trigger cold allodynia.

Conclusion and Implications

Altogether, our data indicate that T‐type channels differentially contribute to the regulation of cold and mechanical hypersensitivity, and raise the possibility that T‐type channel blockers could promote cold allodynia.
AMP‐activated protein kinase in the amygdala and hippocampus contributes to enhanced fear memory in diabetic mice
Authors: Yamagishi Aimi , Yonemochi Naomi , Kimura Ai , Takenoya Fumiko , Shioda Seiji , Waddington John L. , Ikeda Hiroko
Published: September 2024

Background and Purpose

Diabetic patients have an increased risk of psychiatric disorders. Because hyperglycaemia increases L‐lactate in the brain and L‐lactate inhibits AMP‐activated protein kinase (AMPK), this study investigated the role of L‐lactate and AMPK in strengthened fear memory, a model for human psychiatric disorders, in diabetic mice.

Experimental Approach

The diabetic model was mice injected with streptozotocin. Fear memory was measured using the conditioned fear test with low (0.45 mA) or high (0.50 mA) foot shock to cause low and high freezing, respectively. Protein levels of AMPK and phosphorylated AMPK (pAMPK) were measured by western blotting and immunohistochemistry.

Key Results

At 0.45 mA, the AMPK inhibitor dorsomorphin increased freezing, which was inhibited by the AMPK activator acadesine. In contrast, at 0.50 mA, acadesine decreased freezing, which was inhibited by dorsomorphin. In diabetic mice, pAMPK was decreased in the amygdala and hippocampus. Diabetic mice showed increased freezing at 0.45 mA, which was inhibited by acadesine. In the amygdala and hippocampus, L‐lactate was increased in diabetic mice and injection of L‐lactate into non‐diabetic mice increased freezing at 0.45 mA. In addition, L‐lactate decreased pAMPK in the hippocampus, but not the amygdala, and increase in freezing induced by L‐lactate was inhibited by acadesine. Dorsomorphin‐induced increase in freezing was inhibited by the AMPA receptor antagonist NBQX.

Conclusions and Interpretation

In diabetic mice, L‐lactate is increased in the amygdala and hippocampus, possibly through hyperglycaemia, which strengthens fear memory through inhibition of AMPK and activation of glutamatergic function.
Glycaemic and weight effects of metabolic surgery or semaglutide in diabetes dosage for patients with type 2 diabetes
Authors: Stenberg Erik , Cao Yang , Ottosson Johan , Hedberg Suzanne , Näslund Erik
Published: September 2024

Aim

To compare weight and glucometabolic outcomes of semaglutide and metabolic and bariatric surgery (MBS) for patients with type 2 diabetes and obesity.

Materials and Methods

Patients treated with either semaglutide for a duration of ≥2 years or MBS in Sweden were identified within the Scandinavian Obesity Surgery Registry and the National Diabetes Registry and matched in a 1:1–2 ratio using a propensity score matching with a generalized linear model, including age, sex, glycated haemoglobin before treatment, duration of type 2 diabetes, use of insulin, presence of comorbidities and history of cancer, with good matching results but with a remaining imbalance for glomerular filtration rate and body mass index, which were then adjusted for in the following analyses. Main outcomes were weight loss and glycaemic control.

Results

The study included 606 patients in the surgical group matched to 997 controls who started their treatment from 2018 until 2020. Both groups improved in weight and glucometabolic control. At 2 years after the intervention, mean glycated haemoglobin was 42.3 ± 11.18 after MBS compared with 50.7 ± 12.48 after semaglutide treatment (p < 0.001) with 382 patients (63.0%) and 139 (13.9%), respectively, reaching complete remission without other treatment than the intervention (p < 0.001). Mean total weight loss reached 26.4% ± 8.83% after MBS compared with 5.2% ± 7.87% after semaglutide (p < 0.001).

Conclusion

Semaglutide and MBS were both associated with improvements in weight and improved glycaemic control at 2 years after the start of the intervention, but MBS was associated with better weight loss and glucometabolic control.
Genetic Sex and Origin Identification Suggests Differential Migration of Male and Female Atlantic Bluefin Tuna (Thunnus thynnus) in the Northeast Atlantic
Authors: Nielsen Einar Eg , Birnie‐Gauvin Kim , Baktoft Henrik , Arrizabalaga Haritz , Brodin Tomas , Cardinale Massimiliano , Casini Michele , Helström Gustav , Jansen Teunis , Koed Anders , Lundberg Petter , MacKenzie Brian R. , Medina Antonio , Post Søren , Rodriguez‐Ezpeleta Naiara , Sundelöf Andreas , Varela José Luis , Aarestrup Kim
Published: September 2024

Knowledge about sex‐specific difference in life‐history traits—like growth, mortality, or behavior—is of key importance for management and conservation as these parameters are essential for predictive modeling of population sustainability. We applied a newly developed molecular sex identification method, in combination with a SNP (single nucleotide polymorphism) panel for inferring the population of origin, for more than 300 large Atlantic bluefin tuna (ABFT) collected over several years from newly reclaimed feeding grounds in the Northeast Atlantic. The vast majority (95%) of individuals were genetically assigned to the eastern Atlantic population, which migrates between spawning grounds in the Mediterranean and feeding grounds in the Northeast Atlantic. We found a consistent pattern of a male bias among the eastern Atlantic individuals, with a 4‐year mean of 63% males (59%–65%). Males were most prominent within the smallest (< 230 cm) and largest (> 250 cm) length classes, while the sex ratio was close to 1:1 for intermediate sizes (230–250 cm). The results from this new, widely applicable, and noninvasive approach suggests differential occupancy or migration timing of ABFT males and females, which cannot be explained alone by sex‐specific differences in growth. Our findings are corroborated by previous traditional studies of sex ratios in dead ABFT from the Atlantic, the Mediterranean, and the Gulf of Mexico. In concert with observed differences in growth and mortality rates between the sexes, these findings should be recognized in order to sustainably manage the resource, maintain productivity, and conserve diversity within the species.
Decoding machine learning in nursing research: A scoping review of effective algorithms
Authors: Choi Jeeyae , Lee Hanjoo , Kim‐Godwin Yeounsoo
Published: September 2024

Introduction

The rapid evolution of artificial intelligence (AI) technology has revolutionized healthcare, particularly through the integration of AI into health information systems. This transformation has significantly impacted the roles of nurses and nurse practitioners, prompting extensive research to assess the effectiveness of AI‐integrated systems. This scoping review focuses on machine learning (ML) used in nursing, specifically investigating ML algorithms, model evaluation methods, areas of focus related to nursing, and the most effective ML algorithms.

Design

The scoping review followed the Preferred Reporting Items for Systematic Review and Meta‐Analysis Extension for Scoping Reviews (PRISMA‐ScR) guidelines.

Methods

A structured search was performed across seven databases according to PRISMA‐ScR: PubMed, EMBASE, CINAHL, Web of Science, OVID, PsycINFO, and ProQuest. The quality of the final reviewed studies was assessed using the Medical Education Research Study Quality Instrument (MERSQI).

Results

Twenty‐six articles published between 2019 and 2023 met the inclusion and exclusion criteria, and 46% of studies were conducted in the US. The average MERSQI score was 12.2, indicative of moderate‐ to high‐quality studies. The most used ML algorithm was Random Forest. The four second‐most used were logistic regression, least absolute shrinkage and selection operator, decision tree, and support vector machine. Most ML models were evaluated by calculating sensitivity (recall)/specificity, accuracy, receiver operating characteristic (ROC), area under the ROC (AUROC), and positive/negative prediction value (precision). Half of the studies focused on nursing staff or students and hospital readmission or emergency department visits. Only 11 articles reported the most effective ML algorithm(s).

Conclusion

The scoping review provides insights into the current status of ML research in nursing and recognition of its significance in nursing research, confirming the benefits of ML in healthcare. Recommendations include incorporating experimental designs in research studies to optimize the use of ML models across various nursing domains.

Clinical Relevance

The scoping review demonstrates substantial clinical relevance of ML applications for nurses, nurse practitioners, administrators, and researchers. The integration of ML into healthcare systems and its impact on nursing practices have important implications for patient care, resource management, and the evolution of nursing research.