bluuebunny/crossref_metadata_2025 huggingface dataset:
Znaczenie oceny płynności i rentowności w aspekcie zagrożenia ryzykiem upadłości przedsiębiorstw na przykładzie branży górniczo-hutniczej
Authors: Nesterowicz Renata , Nakonieczny Joanna , Nesterowicz Aleksandra
Published: July 2022

Wskaźniki płynności i rentowności dostarczają informacji, które pozwalają ocenić sytuację finansową danej jednostki gospodarczej. Wczesne dostrzeżenie zagrożenia upadłością jest koniecznym wymogiem, który umożliwia podjęcie szybkich czynności naprawczych pozwalających na unikniecie bankructwa. Dzięki temu, że istnieją odpowiednie modele wczesnego ostrzegania przedsiębiorstw przed ryzykiem upadłości, możliwe jest wykrycie zagrożenia poprzez odpowiednie kontrolowanie sytuacji finansowej. Celem artykułu jest próba zidentyfikowania problemów w obszarze płynności i rentowności, które mogą w przyszłości prowadzić do upadłości spółek branży górniczo-hutniczej w Polsce. Na podstawie zebranych, a następnie opracowanych danych ze sprawozdań finansowych zostanie przeprowadzona analiza wskaźnikowa płynności i rentowności oraz zostanie zbudowane modele dyskryminacyjne. Opracowane wyniki umożliwią zweryfikowanie przyjętej hipotezy zakładającej, że branża górniczo-hutnicza w Polsce mierzy się z problemami w obszarze płynności i rentowności, które mogą w przyszłości prowadzić do upadłości spółek. Przeprowadzone badania dowodzą, że ustalone wskaźniki płynności i rentowności znalazły odzwierciedlenie w wynikach analizy modeli dyskryminacyjnych. W sytuacji, gdy wielkości wskaźników były wyższe, modele dyskryminacyjne również przedstawiały wyższe wartości parametru Z. Opracowanie ma charakter opisowo-empiryczny.
Use of CMC Na as Gelling Agent in Nanoemulgel Formulation of Methanol Extract of Sappan Wood (Caesalpinia sappan L)
Authors: Saryanti Dwi , Setiawan Iwan , Dayanto Hendri Hari
Published: July 2022

Sappan wood ( Caesalpinia sappan L.) contains brazilin including isoflavonoids which act as antimicrobials (against bacteria on skin) and antioxidants. Nano technology increases surface area, enhance stability, reduces skin irritation, protects from degradation, and has good drug delivery. Nano emulsion preparations can help permeability of the drug on the membrane surface. Nanoemulgel preparations can provide stability and good drug release compared to mixing drugs directly in a gel base. The purpose of this study were to determine the effect of different concentrations of CMC-Na gelling agents and which concentration of CMC-Na gelling agents that can produce the best nanoemulgel preparations. Nanoemulsion made from isopropyl myristate as oil phase, tween 80 as surfactant and polyethylenglycol as co-surfactant. Nanoemulsion formulations were tested by measurement of % transmittance by UV-Vis spectrophotometry at a wavelength 650nm. Nanoemulgel is made from nano emulsions used basis of CMC-Na at concentrations 3%, 4%, and 5%. The results showed percent transmittance was 71.86%. The results of physical quality and stability tests of the nanomulgel wood preparations showed an influence on the physical properties such as adhesion, dispersion and viscosity, the greater concentration of CMC-Na gelling agents in nanoemulgel preparations, the greater values adhesion and viscosity, while the spreadability was smaller. Concentration of CMC-Na gelling agent that produced the best of sappan wood nanoemulgel ( Caesalpinia sappan L.) was 5% that stable by freeze-thaw testing.
Physicochemical Parameters and Purification of Pulp Effluent (Black Liquor)
Authors: Shokunbi Oluwatosin , Omenka R.O
Published: July 2022

Pulp and paper Industry poses a great significant problem in Environmental pollution and they consume high energy, water and resources. The present study was undertaken to purify pulp effluent (black liquor) using sand bed filters and adsorption method (Activated Carbon). The physicochemical parameters carried out were pH, colour, temperature, turbidity, total alkalinity (TA), total hardness (TH), chemical oxygen demand (COD), total suspended solids (TSS), total solids (TS) and total dissolved solids (TDS) using standard methods by American Public Health Association (APHA). The results obtained for black liquor and treated effluent were; colour (dark brown), pH (11.59 & 9.14), temperature (31 & 30 ), turbidity (1.78 &0.77 NTU), TA (10,000mg/L & 300mg/L), TH (325 mg/L & 220 mg/L), COD (2663 mg/L & 174.85 mg/L), TSS (0.09 mg/L & 0.00 mg/L), TS (0.9 mg/L & 0.17 mg/L), TDS (1354 mg/L) respectively.  Highly significant differences were found between the effluent and treated water. The results indicated that pulp and paper Industrial effluents are highly polluted and can be toxic or harmful to human beings when released into water bodies without being treated.
Cargos em comissão, tecnologia e a efetivação de direitos sociais
Authors: Macedo Rosa Túlio , Frota Sales Kleilson , Rodrigues Jerônimo Elaine
Published: July 2022

O objetivo do presente artigo é avaliar a efetivação dos direitos sociais por meio das limitações constitucionais impostas aos atos discricionários, considerando a natureza comissionada dos cargos ocupados pelos gestores públicos e a possibilidade de que o conhecimento técnico seja fator preponderante nas tomadas de decisão. Para alcançar o destacado objetivo, a pesquisa possui fundamento em referenciais teóricos, jurisprudenciais e históricos, além de análise da doutrina e da normatividade que rege a matéria, com cerne nos axiomas que devem respaldar as decisões discricionárias dos gestores públicos na escolha dos cargos e das funções de livre nomeação e exoneração. Inicialmente, o estudo será focado em apresentar as principais características dos cargos públicos de nomeação discricionária e a vedação ao arbítrio. Após, busca-se verificar como os limites constitucionais à discricionariedade fomentam a efetivação dos direitos sociais por meio da interpretação de julgados do Poder Judiciário. Em seguida, apresenta-se o clientelismo e as balizas à discricionariedade do administrador público. Concluindo o presente estudo, defende-se a utilização de tecnologia de dados e da informação como ferramenta no processo de decisões do administrador público e na transparência dos atos.
Desarrollo del comportamiento creativo a través de un curso de formación para secretarios judiciales
Authors: Farfán Mejía Enrique , Del Pilar Quezada Dora Viridiana , Juárez Juárez Ricardo , Hernández Espinoza Iván
Published: July 2022

El objetivo de esta investigación es identificar el impacto de un curso de formación, sustentado en la retórica, en el desarrollo de comportamiento creativo de secretarios judiciales. El estudio fue realizado en un tribunal de impartición de justicia de la República Mexicana. Se realizó un estudio descriptivo, exploratorio no experimental, con un diseño a-b-a con un pretest y un postest, antes y después de aplicar la variable independiente, un curso especializado. El pretest se aplicó al inicio del curso. El postest se aplicó, al finalizar el curso. La variable independiente, estuvo sustentada en la retórica clásica, para formar secretarios judiciales y la variable dependiente midió el desempeño creativo de acuerdo con el puntaje obtenido en la prueba EMUC. Se demostró que el curso fue favorable para los participantes, ya que la mayoría de los grupos mejoró o quedó en el mismo puntaje en el postest.
Um Balanço da operacionalização do PRONAF em Marabá e suas implicações em um assentamento rural entre 2013 e 2019
Authors: Neves Evandro Carlos Costa , Schmitz Heribert
Published: July 2022

O artigo analisou como a operacionalização do Programa Nacional de Fortalecimento da Agricultura Familiar (PRONAF) se configurou em Marabá, Sudeste do Pará, no septênio 2013-2019 e quais foram suas implicações no Assentamento 26 de Março, localizado nesse município. As questões que nos auxiliaram foram: qual foi o comportamento do Pronaf em Marabá no período analisado? Quais foram suas implicações no Assentamento 26 de Março? Metodologicamente, realizamos levantamento bibliográfico-documental e pesquisas de campo nos anos de 2017 e 2018, com o uso de entrevistas não diretivas e observação participante. Analisamos os dados a partir das abordagens quantitativa e qualitativa. Os resultados permitem afirmar que: (i) o comportamento do Pronaf no município de Marabá foi associado à pecuária bovina entre 2013 e 2019; (ii) e sua operacionalização não contemplou a diversidade dos sistemas produtivos agroecológicos do seu público no Assentamento 26 de Março. No geral, identificamos uma natureza contingente do programa e afirmamos que sua orientação enviesada não fortaleceu seu público. Em razão disso, apontamos algumas possibilidades para operacionalizações futuras.
Impact of financial capital, social capital, and business digitalization on business sustainability of SMEs in Indonesia
Authors: Pardiman Pardiman , Susyanti Jeni , Heriyawati Dwi Fita , Zakaria Zuhkhriyan , Masyhuri Masyhuri
Published: July 2022

SMEs have significant challenges amid a pandemic that is crippling the country's economy to survive and continue to struggle from bankruptcy. So, this paper analyzes the impact of financial capital, social capital, and business digitalization in improving business sustainability and finds out which variables are marketing strategies in mediating the direct influence between these three variables. Data collection using a questionnaire instrument using a survey technique. The research sample was 93 respondents as SME business owners. The research period was carried out from June to September 2021. After the data is collected, then tested using SEM-PLS using Warppls 5.0 software. The study found that financial capital can improve business sustainability, and social capital can also affect business sustainability; the same is valid for business digitization which can improve business sustainability for SME actors. Therefore, SME business actors need to pay attention to the business capital, then social capital to the community in the long term, and digitalization to improve businesses' ability to survive in a pandemic. Furthermore, we hope that this research will expand understanding to SMEs business owners to be more vigilant about several factors that can make a business go bankrupt, especially in a pandemic situation. However, the limitation of this study lies in the research sample, which only examines one province so that future researchers can compare it with other provinces. And in this study, it was found that the marketing strategy has not been successful in mediating, so it still needs to be discussed further.
The mediating role of perceived value and social media word-of-mouth in the relationship between perceived quality and purchase intention
Authors: Widodo Teguh , Krisma Maylina Ni Luh Putu
Published: July 2022

This study aims to investigate the effect of perceived quality on purchase intention mediated by the perceived value and social media WOM. The process involved testing the cause-and-effect relationships between the variables used in the structural equation model (SEM) empirically using primary data from an online survey of 410 Garuda Indonesia Airline passengers. The five-scale ordinal data retrieved from the 27 question items presented to the respondents were later processed using LISREL statistical software. The analysis produced several findings, first, the perceived value dimensions were directly affected by the perceived quality and also have a direct influence on social media WOM, second, social media WOM directly affected purchase intention, third, perceived value dimensions played a mediating role between perceived quality and purchase intention, and fourth, social media WOM had a mediating influencing on the effect of perceived quality on purchase intention. This simply means that perceived quality indirectly and significantly affected purchase intention through the mediation of perceived value dimensions and social media WOM.
On the issue of the sources of alluvial diamonds of the Ebelyakhsky region (Arctic zone of Russia)
Authors:   Institute of Geology of Ore Deposits, Petrography, Mineralogy and Geochemistry of RAS, Bochneva A.A. , Lalomov A.V. ,   Institute of Geology of Ore Deposits, Petrography, Mineralogy and Geochemistry of RAS
Published: July 2022

The work considers the identification of potentially diamond areas based on the geological and statistical analysis of data from heavy mineral concentrate sampling of alluvial deposits of the Ebelakh River and its confluents. The researchers compress the information of the diamond placer mineral field of the Ebelyakh River and identify the main components based on information entropy (K. Shannon). The spatial heterogeneity of polymineral fields, revealed using the entropy method, allow outlining areas of possible localization of intermediate hosts (or their former development) in the Ebelyakhskiy region.
Prospects for the application of ice composite materials for the construction of ice crossings
Authors:   V. P. Larionov Institute of the Physical-Technical Problems of the North of the Siberian Branch of the RAS, Syromyatnikova A.S. , Fedorova L.K. ,   М. К. Ammosov North-Eastern Federal University
Published: July 2022

Ice as a structural material is considered as a pavement material, a substitute for traditional building materials in the northern construction and climatic zone. Improvement in ice strength can be achieved by macro- and micro-reinforcement. In the North and the Arctic conditions, materials of natural origin from local raw materials are economically and technologically effective and environmentally friendly types of reinforcing fillers. The authors investigate the possibility of using natural fibrous fillers (hay fibers and basalt fiber) in an ice matrix as a reinforcing additive. They demonstrate that the introduction of the used fillers leads to a two-, three-fold increase in the bending strength of fresh ice. Ice composite materials can be used as materials for construction and engineering purposes, as well as a pavement material applied in the Arctic regions. The authors carry out a predictive assessment of the reduction in the permitted time for the start-up of an ice crossing from such composite materials through northern water bodies and show that the strengthening of the ice crossing by layer-by-layer freezing of a mixture of water and basalt fiber will lead to a significant reduction in the indicated terms.
The effectiveness evaluation of implementing micro-hydroelectric power plants for the ecotourism development in remote areas of the Arctic zone of the Russian Federation (on the example of the Murmansk region)
Authors:   Northern Energetics Research Centre Kola Science Centre of the Russian Academy of Sciences, Bezhan A.V. , Konovalova O.E. ,   Northern Energetics Research Centre Kola Science Centre of the Russian Academy of Sciences
Published: July 2022

The article considers the problem of power supply to remote ecotourism areas of the Murmansk region. In such areas, diesel generators are used to supply tourist complexes, the fuel for which is mainly delivered by helicopters, which is the reason for the high cost of electricity. At the same time, the operation of diesel generators is accompanied by harmful emissions into the environment, which contradicts the principles of ecotourism, where human influence on nature implies actions related to the preservation of nature in its natural state. Using the example of two tourist complexes “Acha” and “Pacha”, the authors suggest one of the solutions to these problems: the use of micro-hydroelectric power plants together with diesel generators. They outline that in this case the main effect is expressed in fuel economy and, as a result, in 1.5-fold reduction in the cost of electricity generated. Also, due to fuel economy in the two tourist complexes considered, carbon dioxide emissions will be reduced by a total of 29 tons per working season. The discounted payback period of micro-hydroelectric power plants will be about 2 years.
Development of the congress and exhibition industry in the Russian Federation
Authors: Dunenkova E. N. , Isayeva M. I.
Published: July 2022

Existing trends are pushing for the emergence of new approaches in the organization of congress and exhibition events, the work of exhibition complexes in Russia and the world. The development of the industry is aimed at introducing a hybrid format of participation, which emphasizes the potential and importance of exhibitions for the restoration of the economic state of the state. The congress and exhibition industry plays the role of a locomotive for industrial, technological, economic, scientific and innovative directions. The successful functioning of the industry is important for achieving a synergistic effect on the socio-economic development of the state and regions. Through congress and exhibition events, the state receives an additional source of income for the federal and regional budgets. Based on the research of the Russian Union of Exhibitions and Fairs, in Russia, congress and exhibition events generate about 3.2 trillion rubles or 3 % of the state’s GDP.
Role of electric transport in urban transportation system
Authors: Sakulyeva T. N. , Sotnikova V. V.
Published: July 2022

The purpose of the article is to identify the tasks and problems of city transport systems in modern conditions. Urban transport should solve the following tasks: equal access to the population to vehicles, the possibility of planning the time of traveling inside the city, ensuring environmental safety from the use of vehicles, creating the conditions for the availability of transport services at their cost, security and comfort, as well as ensure transport services for the business subjects at minimal economic costs. In the process of applying analytical research methods, urgent problems of urban transport were identified and areas of solving these problems were proposed. Electric transport is really economically more profitable in large cities and in urban agglomerations with high population density, when there is no urgent need to move often over long distances. The total benefits from the transition to electric vehicles are largely higher than the costs. Due to the improvement of the environmental situation, not only the quality of life of the population increases, but the capitalization of all production and public facilities in the country is growing.
Foreign experience in the use of а digital tools in regions and cities in the pandemic context
Authors: Sergienko N. S.
Published: July 2022

The COVID-19 crisis has accelerated separate megatrends and transformations not only in the social sphere, but also in the digital one in the public administration system. Information exchange, electronic participation and two-way communication using digital platforms allowed public authorities and business structures to respond promptly to the crisis in the short term. The urgency of the issues to be solved determined the adoption of measures not only in the short term prospect, but also indicated the need to develop them for the medium and long term period. The aim of the study was to analyse and systematise the set of measures taken by public authorities in different countries, in the mobilisation and crisis management of COVID-19. An important aspect of the study seems to be the identification of directions for digitalisation and further state and municipal digital services modernisation. The analysis of the measures taken by public authorities in different countries has highlighted that the policy of accelerating the digitalization of public administration and the public services provision in regions, cities and rural areas had helped to solve the social and economic problems. The regional and local measures versatility in different countries on digitalization in the medium term prospect makes it possible to form common approaches for using this experience in order to further modernize state and municipal digital services.
The phenomenon of children’s emotional burnout in a children’s health camp
Authors: Panina S. E. , Nikitin A. V. , Samykina N. Yu.
Published: July 2022

In this article, there are considered concepts of emotional and professional burnout, carried out their differentiation, based on the scope of their manifestation and the specifics of the type of activity. That raised the problem of the possibility of the existence of emotional burnout of children, which predictor may be the educational environment, and it has a significant impact on the psychological well-being of the subjects of the educational process. The purpose of the study was to identify the existence of emotional burnout of children in the educational environment. To achieve it, the authors proposed and implemented the following tasks: 1) to highlight the specific features of summer camps as an educational environment; 2) to determine the preconditions leading to the emotional burnout of children in the educational environment; 3) to adapt the methodology for diagnosing emotional burnout of children; 4) to measure the levels of emotional burnout at the beginning and at the end of the session in camp and to compare the identified indicators using methods of mathematical statistics (Student’s t-test for dependent samples). The adapted russification of the Maslach Questionnaire (MBI) by N.E. Vodopyanova was used on a sample of 10 to 16 years old. The result of empirical research demonstrated the existence of emotional burnout of children and opened the perspectives for research into the phenomenon of children’s emotional burnout.
Dynamics of socio-economic indicators development of federal districts of Russia
Authors: Gerasimenko N. A.
Published: July 2022

The article presents the results of a study of the dynamics of the main indicators of the socio-economic development of the federal districts of Russia for the period 2005–2020, which caused the presence of problems associated with the uneven spatial development of the country and correlated with the standard of living of the population. It is shown that the excessive unevenness of the economic development of regions has the most negative effect on their social condition. As part of the study, the analysis of socio-economic indicators in the context of federal districts was carried out on the basis of statistical data from Rosstat, which ensured their comparability for different periods of observation. Long-term trends have been identified, indicating a steady increase in the level of differentiation of a number of indicators between federal districts. The study allowed us to identify three groups of federal districts of Russia, showing: accelerated growth of indicators of socio-economic development above the average level in Russia; relatively insignificant growth rates; the increasing decline in indicators.
Metabolomics of Non-Saccharomyces Yeasts in Fermented Beverages
Authors: Ellis Daniel , Kerr Edward , Schenk Gerhard , Schulz Benjamin
Published: July 2022

Fermented beverages have been consumed for millennia and today support a global industry producing diverse products. Saccharomyces yeasts currently dominate the fermented beverage industry, but consumer demands for alternative products with a variety of sensory profiles and actual or perceived health benefits are driving the diversification and use of non-Saccharomyces yeasts. The diversity of flavours, aromas, and other sensory characteristics that can be obtained by using non-Saccharomyces yeasts in fermentation is, in large parts, due to the diverse secondary metabolites they produce compared to conventional Saccharomyces yeast. Here, we review the use of metabolomic analyses of non- Saccharomyces yeasts to explore their impact on the sensory characteristics of fermented beverages. We highlight several key species currently used in the industry, including Brettanomyces, Torulaspora, Lachancea, and Saccharomycodes, and emphasize the future potential for the use of non- Saccharomyces yeasts in the production of diverse fermented beverages.
Expedient Synthesis of a Library of Heparan Sulfate Like “Head to Tail” Linked Multimers for Structure and Activity Relationship Studies
Authors: Zhang Jicheng , Liang Li , Yang Weizhun , Ramadan Sherif , Baryal Kedar , Huo Chang-xin , Bernard Jamie , Liu Jian , Hsieh-wilson Linda , Zhang Fuming , Linhardt Robert , Huang Xuefei
Published: July 2022

Heparan sulfate (HS) plays significant roles in various biological processes such as inflammation, cell proliferation, and bacterial and viral infection. The inherent complexity of naturally existing HS has severely hindered the thorough understanding of the relationship between their diverse structures and biological functions. While HS syntheses have advanced significantly in recent years, preparation of HS libraries remains a tremendous challenge due to the difficulties in achieving high yields in glycosylation and sulfation reactions especially with longer glycans and the need to prepare multiple compounds. A new strategy to synthesize a library of HS-like pseudo-hexasaccharides has been developed to expedite library preparation. HS disaccharides were linked in a “head-to-tail” fashion from the reducing end of a module to the non-reducing end of a neighboring module to mimic native HS. Three differentially sulfated HS disaccharides were designed and prepared from a common intermediate. Conjugation of these modules using amide chemistry bypassed the need for challenging glycosylation reactions to extend the HS backbone. Combinatorial syntheses of 27 HS-like pseudo-hexasaccharides were achieved using these three HS modules. This new class of compounds mimicked well the native HS with their binding to fibroblast growth factor 2 (FGF-2) exhibiting similar structure-activity relationship trends as HS hexasaccharides. The ease of synthesis and the ability to mimic natural HS suggest the new head-to-tail linked pseudo-hexasaccharides could be an exciting tool to facilitate the understanding of HS biology.
Racemic and Meso Diastereomers of a P-Chirogenic Diboranyldiphosphinoethane
Authors: Austen Brady , Sharma Harvey , Zurakowski Joseph , Drover Marcus
Published: July 2022

Diphosphine ligands have enjoyed great success as sup-porting moieties for transition elements, where modifica-tion of both primary and secondary coordination sphere has been shown to illicit differences in chemical reactivi-ty. This work describes a new family of such ligands con-structed from the previously reported scaffold, (±)-rac/meso-(t-Bu)ClP-CH2CH2-PCl(t-Bu) that bears bulky tert-butyl substituents. Reaction of this precursor with allyl magnesium chloride and subsequent hydroboration using HBCy2 (Cy = cyclohexyl) provides access to a di-boranyldiphosphinoethane – the first in a class of ligands having two electrophilic boranes in their secondary coor-dination sphere. As a testing ground for coordination, these motifs (and their allyl precursor) have been in-stalled at Ni(0) using [Ni(COD)2] (COD = 1,5-cyclooctadiene) in order to determine methods for clean installation. Product stereochemical outcomes are in some cases complicated and have been determined by NMR spectroscopic and crystallographic means. Density func-tional theory optimizations and accurate DLPNO-CCSD(T) energy calculations were also performed to sup-port structural assignment.
Squarephaneic Tetraanhydride: A Conjugated Square-Shaped Cyclophane for the Synthesis of Porous Organic Materials
Authors: Eder Simon , Thornton Daisy B. , Ding Bowen , Sammut Darlene , White Andrew J. P. , Plasser Felix , Stephens Ifan E. L. , Heeney Martin , Mezzavilla Stefano , Glöcklhofer Florian
Published: July 2022

Aromatic carboxylic anhydrides are ubiquitous building blocks in organic materials chemistry. In particular, dianhydrides and their conversion into imides have received considerable attention in the synthesis of organic semiconductors, pigments, and battery electrode materials. Here we extend the family of aromatic carboxylic anhydrides with a unique new member, a conjugated cyclophane with four anhydride groups. The cyclophane, named squarephaneic tetraanhydride due to its square shape, is obtained in a three-step synthesis; the anhydride groups are located at the corners and allow for efficient functionalisation, as shown by the conversion into imides and carboxylates. The crystal structures of the tetraanhydride and one of the imides demonstrate the high degree of porosity achievable with the new building block. Electrochemical measurements in solution and solid state are also presented. Considering the short synthesis and unique properties, we expect widespread use of the new building block in the development of organic materials.
Putative G-quadruplex Formation in the Upstream Region of mTOR Gene
Authors: Dash Jyotirmayee , Fatma Khushnood , Saha Puja , Das Tania
Published: July 2022

The mammalian target of rapamycin (mTOR) and its signaling pathways are highly critical for maintaining cell homeostasis. The mTOR signaling pathway is often hyperactivated in many types of cancers making it an attractive therapeutic target for cancer. The efficacy of current mTOR protein inhibitors in therapy has seen limited success. The search for alternative means of therapy may lie in the regulation of mTOR gene expression using DNA structures. In the current study, we explore and report the presence of a novel G4 structure in the upstream region of mTOR gene. We have demonstrated the G-quadruplex formation in the mTOR G4 region using biophysical experiments. This study paves the way for the design of novel selective DNA G4 binders for mTOR G4 for anticancer therapeutics.
Seasonal Variability of the Concentration of Chloride Ions in the Water of the Kuibyshevsk Reservoir
Authors:   Institute of Ecology of the Volga Basin RAS – Branch of the Samara Federal Research Center RAS, Selezneva K. V. ,   Togliatti State University, Selezneva A. V. ,   Institute of Ecology of the Volga Basin RAS – Branch of the Samara Federal Research Center RAS, Seleznev V. A. ,   Institute of Ecology of the Volga Basin RAS
Published: July 2022

According to long-term observations in the period 2001–2019. regularities of seasonal variability of the content of chlorides in the water of the Kuibyshev reservoir were studied. Stationary hydrochemical observation point is located in the outlet section of the reservoir. To study the causes of seasonal variability in chloride concentrations, hydrological data were used at the inlet (Cheboksary and Nizhnikamsk waterworks) and outgoing (Zhigulevsk waterworks) sections of the Kuibyshev reservoir. It was found that over the 19-year observation period, the range of seasonal fluctuations in average monthly chloride concentrations was 14–42 mgdm3. Seasonal variability of chloride content is pronounced and is characterized by alternating maxima and minima of chloride concentration. The winter maximum is observed in April before the beginning of the spring flood, and the summer maximum is observed in July before the beginning of the autumn low water. The spring minimum is observed in May at the peak of the spring flood, and the autumn minimum is observed in December before the freeze-up begins. The seasonal variability of chlorides includes four periods (I, II, III, IV), which are formed as a result of the interaction of genetically heterogeneous water masses in the reservoir. Period I is characterized by a gradual increase in the concentration of chlorides due to the inflow of groundwater during the winter low water. The short-term period II is characterized by a sharp decrease in the concentration of chlorides due to the entry of soil-surface waters into the reservoir during the spring flood. Period III is characterized by an increase in the concentration of chlorides due to an increase in the role of soil and groundwater during the summer low water period. Period IV is the longest and is characterized by a gradual decrease in the concentration of chlorides during the autumn low water period. The revealed patterns of seasonal variability of chlorides are unchanged and were observed annually during 2001–2019. However, the values of chloride concentrations significantly depended on the hydrometeorological conditions of a particular year. In dry years, the concentration of chlorides increased, and in high-water years, they decreased in all hydrological seasons of the year.
Features of Spatial Transformation Agglomerations (on the Example Irkutsk and Ulaanbaatar)
Authors:   V. B. Sochava Institute of Geography SB RAS, Dugarova G. B. , Bogdanov V. N. ,   V. B. Sochava Institute of Geography SB RAS
Published: July 2022

This publication is about the study of urban agglomerations (Irkutsk and Ulaanbaatar). The purpose of this work was, on the one side, to study the features of the transformation of urban spaces based on a comprehensive comparative geographical analysis, and on the other side, to generalize and structure the previously obtained results, as the promotion of scientific ideology. In the during of the study, geoinformation mapping methods were widely used, which provide great opportunities for detecting spatial changes. As a result of the study, based on a comparative geographical analysis of urban agglomerations, both common similar features and problems, as well as specific features that have a significant impact on the transformation of the urban environment, have been identified. Other things being equal, the metropolitan agglomeration has financial, social, economic, logistical op- portunities than the regional one, as a result of which they have different rates and ways of further development. The comparative analysis carried out and the results obtained will be useful and interesting for finding new ways, algorithms for solving common problems.
The Results of Field Measurements of Methane Flux from Various Reservoirs
Authors:   A. M. Obukhov Institute of Atmospheric Physics RAS, Grechushnikova M. G. ,   M. V. Lomonosov Мoscow State University, Repina I. А. ,   A. M. Obukhov Institute of Atmospheric Physics RAS,   M. V. Lomonosov Мoscow State University, Lomova D. V. ,   Institute of Water Problems RAS, Lomov V. А. ,   M. V. Lomonosov Мoscow State University
Published: July 2022

The article presents the results of measurements of the specific flux of methane from the surface of different types of reservoirs on the ETR in August 2021. The selected reservoirs (Ivankovskoye, Tsimlyanskoye and Chirkeyskoye) differ in flow rate, climatic features, and anthropogenic load. The main factors of differences in the specific flux of methane from the surface of water reservoirs, which amounted to 10.5–334, 13–183, 0–1,3 mgCm2*day respectively for the Ivankovskoe, Tsimlyanskoe and Chirkeyskoe reservoirs, were revealed. Spatial differences in methane content and emissions are determined by the nature of the bottom sediments, the depth of the station, the productivity of the reservoir, the presence of stratification and oxygen-free conditions in the bottom layer. The emission from the surface of each reservoir was estimated. Despite the fact that the largest specific flux was measured at the Ivankovskoe reservoir, its contribution to atmospheric emissions is 43 times less than that of the Tsimlyanskor reservoir due to its smaller area. A relatively insignificant methane emission in absolute magnitude was detected for the Chirkeyskoye reservoir, despite the fact that the capacity of Chirkeyskaya HPP is 4.7 times greater than the Tsimlyanskaya HPP and 33.3 times greater than the Ivankovskaya HPP. When estimating global methane emissions, when using empirical dependencies or the analogy method to estimate emissions from unexplored reservoirs, it is extremely important to take into account not only the climatic zone in which the reservoir is located and its own characteristics, but also the conditions for the formation of runoff in the catchment and its landscape features.
PROPAGATION STRATEGIES FOR THE VULNERABLE MEDICINAL TREE SPECIES, HILDEGARDIA POPULIFOLIA (ROXB.) SCHOTT & ENDL. (MALVACEAE)
Authors: M Saradh
Published: July 2022

Development of propagation and conservation strategies for the vulnerable tree species, Hildegardia populifolia is a reference book focused at post graduates, research scholars, scientists and professionals of tree species cultivation. It covers the macropropagation through clonal cuttings and micropropagation in terms of direct and indirect regeneration and synthetic seed propagation. It is specifically directed to biotechnologists, biologists and bioengineers working in research institutes, universities or at various institutions
Transfer pricing as a means of minimizing tax manipulation in operations with non-residents
Authors: Lehenchuk S.F. , Zhyhlei I.V. , Orlov I.V.
Published: July 2022

The article examines current trends in transfer pricing as a means of minimizing tax manipulation, including operations with non-residents. The concept of transfer pricing and controlled transactions, the criteria that indicate that the transaction is under control, including operations with non-residents has been disclosed. The methods of establishing compliance with the conditions of the controlled operation of the «outstretched arm» principle and the basis for their application, as well as penalties in the field of transfer pricing have been analyzed. The international and domestic regulatory framework for transfer pricing has been considered, the features of globalization of tax legislation in this matter have been identified. Features of the subjectivity of national legislation in the field of transport pricing have been highlighted and ways to minimize the risk of enhanced monitoring by regulatory authorities have been presented. The changes that have taken place in transfer pricing since the beginning of the COVID-19 pandemic have been disclosed.
Keberadaan Jenis Kacapi dalam Ganre Kesenian Tradisional Sunda
Authors: Ruswandi Tardi , Nugraha Asep , Ekagustdiman Dody Satya
Published: July 2022

Alat musik petik tradisional di Sunda dikenal dengan sebutan kacapi telah tampil melewati perjalanan ruang dan waktu yang sangat panjang. Instrumen ini telah berhasil mewariskan nilainilai estetik musikal pada musik Karawitan di Sunda. Namun pada masa sekarang disenyalir beberapa alat musik petik tradisional di Sunda ini ada yang sedikit termarginalkan karena tidak lagi digunakan dan difungsikan dalam kehidupan sosial budaya masyarakatnya. Padahal tidak semua orang Sunda yang sudah mengenal dengan baik setiap alat musik petik tradisional yang mereka miliki. Tulisan ini bertujuan untuk memberikan gambaran mengenai keberadaan alat musik petik tradisional di Sunda atau kacapi. Metode yang digunakan adalah kualitatif dengan pendekatan deskriptif analisis, bermaksud agar kerja penelitian menjadi efisien dalam memecahkan masalah dalam penelitian, karena adanya pendeksripsian dan analisis. Penelitian ini menghasilkan sintesa bahwa alat musik tradisional yang ada di Sunda adalah kacapi baduy, kacapi jentréng Rancakalong dan Cibalong Tasikmalaya, kacapi pantun, kacapi indung cianjuran, dan kacapi wanda anyar. Rekomendasi dari hasil penelitian adalah kerja kreatif agar alat musik ini tetap eksis mengarungi waktu di masa yang akan datang.Kata kunci: kacapi, penelusuran, Sunda.
Whole-Genome Based Molecular Characterization of Stenotrophomonas maltophilia. (c2020)
Authors:   ,   Lebanese American University, Ibrahim Asalia
Published: July 2022

Stenotrophomonas maltophilia is a rod-shaped Gram-negative emerging opportunistic pathogen. It causes community and nosocomial infections and is most often recovered from respiratory infections. The organism infects severely ill or immunocompromised individuals and is intrinsically resistant to multiple antibiotics along with the development of acquired resistance through horizontal gene transfer. In this study, we used whole-genome sequencing (WGS), for the in depth molecular characterization of six clinical S. maltophilia isolates collected from hospitals in Lebanon during 2018-2019. Disk diffusion assay was used to determine resistance patterns which were confirmed through in silico detection of relevant genes. All the isolates were resistant to tetracycline, ticarcillin, and imipenem. The β-lactamase blaL1, and the aminoglycoside aac(6’)-Iz and aph(3’)-IIc resistance determinants were detected in the studied isolates. Nucleotide sequences for virulence determinants were downloaded from NCBI and blasted against the isolates whole-genomes. Results showed the presence of a number of extracellular enzymes and other virulence factors (VFs) such as hemolysins and siderophores. The IslandViewer database was used to detect the number of genomic islands (GIs) and the gene pool. Isolates were found to harbor between 20 and 29 GIs each. The GIs were highly diverse and carried multiple VFs. The relatedness between the isolates was investigated through multi-locus sequence typing (MLST), whole genome SNP-based analysis, and pulse field gel electrophoresis (PFGE). We reported three novel STs (ST639, ST640, and ST641). Two quorum sensing rpfF gene variants were detected and which were found to control biofilm formation. Our study is the first of its type in Lebanon and it helped in characterizing and identifying at the molecular level resistance and virulence patterns of an important globally emerging human pathogen. Prevention of related infections depends on establishing and developing infection-control strategies while controlling antibiotic use and environmental reservoirs.
FIRMS' ATTRIBUTES AND FINANCIAL PERFORMANCE OF QUOTED COMPANIES: EVIDENCE FROM NIGERIA
Authors:   Department of Accounting, Babcock University, Ilishan-Remo, Nigeria, Akenroye Christopher Taiwo , Adegbie Folajimi Festus ,   Department of Accounting, Babcock University, Ilishan-Remo, Nigeria, Owolabi Sunday Ajao ,   Department of Accounting, Babcock University, Ilishan-Remo, Nigeria
Published: July 2022

The survival, stability, sustenance and going concern objectives of corporate entities in competitive business environment are driven by uniquely formulated financial performance strategy to drive the achievement of consistent and positive growth. However, firms’ improper utilization of internal attributes has given rise to stunted corporate growth rate, declining net profit margin and negative capital employed performance among listed firms in Nigeria. This study investigates the effect of firms’ attributes on financial performance measures of selected listed companies in Nigeria. The study adopted ex-post facto research design. The population of the study comprised 161 listed companies in Nigeria as at 31st December 2020. A sample size of 111 was purposively determined for the study. Multistage techniques (stratification and quota) were utilized in selecting the 111 firms studied. Secondary data extracted from the published audited financial statements for 10-year period (2011–2020) were used for the study. Descriptive and inferential (multiple regression) statistics were employed to analyze the data. Findings revealed that firms’ attributes had joint significant effect on Net Profit Margin (Adj. R2 = 0.0073, F(3, 1106) = 6.45, p < 0.05) and on Capital Employed Performance (Adj. R2 = 0.018, F(3, 1106) = 31.18, p < 0.05). The study concludes that firms’ attributes drive the achievement of optimal corporate financial performance. The study recommends that firms should continue to use their varied firms’ attributes to deepen their financial performance growth.
KNOWLEDGE, PERCEPTION AND ATTITUDE OF UNDERGRADUATES TOWARDS INTIMATE PARTNER VIOLENCE IN ENUGU METROPOLIS
Authors:   University of Nigeria, Enugu Campus Institute for Development Studies, Umoh Boniface Denis , Chinedum- Ezor Chinedum ,   Department of Sociology Caritas University, Enugu
Published: July 2022

This study investigated the knowledge, perception and attitude of undergraduates towards intimate partners’ violence in Enugu Metropolis, Nigeria. A total of 400 randomly selected undergraduates took part in the study. Findings showed a knowledge gap about Intimate Partner Violence (IPV) among university undergraduates- supposedly knowledgeable young persons in Enugu Urban. Females were more knowledgeable than males which may be indicative of the fact that most often they are the victims. Victims of IPV among the undergraduates rarely report the infraction to the university authorities, which further encourage its perpetuation. Reasons for not reporting IPV include the fear of reprimands by victim’s parents or school authorities or further escalation. It was also found that IPV was not dependent on the number of years that victims had been in the relationship. Given the seeming unwillingness of majority of victims of IPV to report the breaches to appropriate authorities, it is concluded that curbing the menace would require commensurate sanctions and massive education of the population. It is on this note that this study recommends that IPV and gender violence as a whole be taught as one of the general courses in the universities to create more awareness on its prevalence, impact on the health and general well being of the victims. Furthermore, the authorities of universities should liaise with organizations handling issues of IPV and human rights to create centers in the universities where students can walk in and make complaints regarding IPV which would be rigorously investigated and addressed.
IMPACT OF MASS MEDIA MESSAGING ON COMPLIANCE WITH COVID-19 SAFETY PROTOCOLS AMONG RESIDENTS OF OSOGBO, OSUN STATE, NIGERIA
Authors:   Department of Mass Communication Adeleke University, Ede, Olawunmi Bisi , Babatunde Femi O. ,   Department of Mass Communication Adeleke University, Ede
Published: July 2022

This study seeks to investigate the efficacy of media information dissemination during a pandemic. The study adopted the survey method with the questionnaire as research instrument. A sample size of 300 Osogbo residents was drawn through non-probability convenience sampling techniques. Descriptive analysis was employed in the analysis of the obtained data. Findings from the study shows that 60% of respondents are persuaded to comply with the COVID-19 safety protocols as a result of mass media messaging on the pandemic and that wearing of facemask is where the media placed emphasis. Another major finding of the study is that 195 respondents (65%) were not vaccinated compared to 105 (35%) vaccinated. The reason for non-vaccination ranges from non-belief in the efficacy of vaccine to non- availability. The study recommends reinforcing COVID-19 safety campaign messages on other platforms and urges the government to devise means of curtailing news and misinformation on COVID-19 pandemic, especially on the social media.
ASSESSING THE IMPACT OF SUSTANAILBILTY PRACTICES ON FINANCIAL STABILITY OF LISTED NON-FINANCIAL COMPANIES USING ALTMAN Z- SCORE IN SUB-SAHARAN AFRICA
Authors:   Department of Accounting, Babcock University Ilishan-Remo, Nigeria, OGUNLALU Adewale Emmanuel , AKINTOYE I.R ,   Department of Accounting, Babcock University Ilishan-Remo, Nigeria, NWAOBIA A. N. ,   Department of Accounting, Babcock University Ilishan-Remo, Nigeria
Published: July 2022

The study assessed the impact of sustainability practices on financial stability of listed non- financial companies using Altman Z-score ratio in Sub-Sahara Africa countries. Ex-post facto research design was adopted in the study due to the use of secondary data. The population for the study consists of all 183 listed non-financial companies in Ghana, Nigeria and South Africa as at December 31, 2020. The sample of 30 firms consists of 10 most capitalised companies for each of the countries for a period of 10 years (2011 to 2020) was selected using simple random sampling technique. Secondary data collection procedure was adopted and data analysis was carried out using ordinary least square, random effect or fixed effect regression analysis. The findings of the study showed that all the proxies of sustainability practices except SSP were found to have a positive contribution with Z-score ratio of listed non-financial companies in sub-Sahara Africa. Furthermore, study found that firm size and age moderated the effect of sustainability practices on have moderating significant effect of explanatory variables on the explained variable. It was recommended among other things that financial experts should adopt Altman Z-score to measure the impact of sustainability practices on financial stability in sub-Sahara Africa in order to enhance financial stability as one of the conditions for economic development and growth