bluuebunny/crossref_metadata_2025 huggingface dataset:
Tendiendo puentes entre la investigación y la salud pública
Authors: Cabezas César , Ramos-Castillo José
Published: March 2019

La preocupación médica con los trópicos casi era una obsesión para los médicos militares de las colonias europeas durante las últimas décadas del siglo XIX, y aun actualmente las enfermedades llamadas tropicales continúan siendo un serio problema de salud pública en muchos países del mundo, en Latinoamérica y en particular en nuestro país -acentuados últimamente por el cambio climático-, por lo que el abordaje de estas enfermedades requiere un gran esfuerzo en términos de las estrategias que deben implementarse así como las alianzas entre todos los actores para alcanzar una mejor prevención y control de ellas.
Sífilis materna y complicaciones durante el embarazo
Authors: Neira Varillas Milagros Rocío , Donaires Toscano Luis Fernando
Published: March 2019

La sífilis es una infección curable causada por una bacteria llamada Treponema pallidum, se trasmite por vía sexual y también, durante el embarazo, de la madre al feto; y la ausencia de tratamiento en el embarazo conduce a resultados adversos como la muerte fetal tardía, prematuridad y muerte neonatal. Se describe el curso natural de un caso de sífilis materna que curso con complicaciones durante el final del embarazo y conllevó a muerte neonatal.
Lesiones en cavidad oral en pacientes con VIH en un estado del sur de México
Authors: Chorley-Sánchez Josymar , Nájera-Ortiz Juan Carlos
Published: March 2019

Objetivo: Determinar la frecuencia de lesiones de la cavidad oral en personas portadoras de VIH que son atendidas en la unidad médica “Centro Ambulatorio para la prevención y atención en SIDA e Infecciones de Transmisión Sexual” (CAPASITS) de la ciudad de Tuxtla Gutiérrez, Chiapas; México. Métodos: Se realizó un estudio observacional, transversal y prospectivo en pacientes con diagnóstico reciente de VIH, que incluyó la revisión clínica bucal. Resultados: Se incluyeron a 58 pacientes con diagnóstico de infección por VIH que asistieron al centro en el periodo de junio 2016 a marzo del 2017, siendo 75,9% hombres, con 31,6 años en promedio, el 55,2% declaró ser heterosexual y con un nivel de instrucción primaria (42,9%). El grupo de patologías bucales con mayor frecuencia encontrada fueron las micóticas (89,7%), seguida de las bacterianas (72,4%) y virales (65,5%); las lesiones más frecuentes fueron la candidiasis pseudomembranosa (98,1%), la leucoplasia vellosa (60,3%) y el eritema gingival (56,9%). Conclusiones: El 77,6% presentaron de dos a cuatro lesiones, por lo que las lesiones presentes en cavidad oral pueden ser indicadoras del nivel del estado inmunológico de un individuo, por lo tanto, el odontólogo puede ser el primer profesional de salud en sospechar la presencia de la infección por VIH.
Conocimientos, actitudes y prácticas de normas de bioseguridad y riesgo biológico en odontólogos de práctica privada de tres ciudades de Nicaragua
Authors: Paz Betanco Manuel Amed
Published: March 2019

Objetivo: Describir los conocimientos, actitudes y prácticas de normas de bioseguridad y riesgo biológico en odontólogos que ejercen su práctica privada en tres ciudades de Nicaragua, durante el año 2017. Métodos: Se realizó un estudio descriptivo transversal con 86 dentistas seleccionados con la técnica bola de nieve a través de un muestreo no probabilístico y por conveniencia en las ciudades de Managua,Chinandega y León; a los cuales se le aplicó un cuestionario semiestructurado previamente validado. Los datos fueron procesados utilizando estadística descriptiva mediante frecuencias y porcentajes de las variables en estudio. Resultados: Los odontólogos conocen el concepto de riesgo biológico en un 98,8%, pero no el nombre específico de los agentes infecciosos y las vías de entrada de éstos al organismo (76,7%), realizan el lavado de manos frecuente antes y después de cada procedimiento dental (60,4%) y tienen nociones básicas de actuación ante accidentes percutáneos en un 48,8%, la mayoría responde a buenas actitudes de desinfección y esterilización de instrumentales y equipos 78% y 68,6%, así como bioseguridad personal (98,8%). La ciudad de Managua resalta por el adecuado manejo de residuos bioinfecciosos. Conclusiones: Los dentistas presentaron un conocimiento regular, una actitud positiva y buenas prácticas de bioseguridad.
Žinių kūrimo ir dalijimosi jomis poveikis inovacijoms
Authors: Atkočiūnienė Zenona Ona Ona , Petronytė Aurelija
Published: March 2019

[full article and abstract in Lithuanian; abstract in English]

After data analysis, it was concluded that knowledge management in an organization is an important factor that makes a positive contribution to the organization’s activities. Systematically organized knowledge management in an organization is ensured by the application of a knowledge management cycle, model or process. In order to gain a competitive advantage, it is important for the organization to carry out innovative activities, which is determined by consistent knowledge creation and sharing in the organization. It is important that the knowledge conversion model is closely linked to innovation. Systematic knowledge creation and sharing improves the development of new products in organizational projects, which increases the organization’s competitiveness. The results obtained using the empirical quantification method showed that knowledge creation and sharing have a positive effect on innovative behavior.
Žinių vadybos reikšmė viešojo sektoriaus inovatyvumui
Authors: Vaitkevičius Viktoras
Published: March 2019

[full article and abstract in Lithuanian; abstract in English]
One of the most relevant topics discussed in the global political arena is the economic development and the competitiveness of regions and states. In analyzing national and European research on economic development, it is evident that the main criteria for assessing the competitiveness of a country are innovation and the factors that stimulate its development. It is widely acknowledged that organizational knowledge and effective knowledge man­agement are the cornerstone of innovation in all types of organizations. Over the past 20 years, the public sector has undergone significant changes. A switch from the traditional bureaucratic approach to a more managerial one has been noticed. The activities of organizations in this sector are exceptionally knowledge-based; therefore, the application of knowledge management methods is a tool that organizations can promote innovation with to increase operational efficiency. This article, based on scientific literature, analyzes the importance of knowledge management for innovation within the public sector.
Tradicinių, elektroninių ir daugiakanalių pardavimų metodų ir rezultatų sąryšio vertinimo teoriniai aspektai
Authors: Piatkovskytė Gytė , Ulbinaitė Aurelija
Published: March 2019

[full article and abstract in Lithuanian; abstract in English]

Companies are now operating in a globalized era, with constantly developing and rapidly growing infor­mation and communication technologies, with many transformations in communication forms and with intellectual capital- and knowledge-based competition aspects. Due to this, the choice of sales approaches is an essential part of the sales process, which determines the performance results, measured in terms of the efficiency of the companies, cooperation, market share, and other indicators. Before making decisions regarding the choice of the sales approach with which the end-user will be reached, or before making the decision to change the approach of sales, or after such a change, it is necessary for companies to assess the detailed impact thereof on their performance. This article highlights a holistic approach to decision-making related to the importance of choosing or modifying sales approaches, the importance of assessing the relationship between sales approaches and multi-threaded results on the needs of the market and operational efficiency, on the need of better access to markets and consumers, and successful business activities. After a systematic comparative analysis of the scientific literature, the theoretical model, which allows for estimating the relationship between business results and sales approaches through which end-users are reached, was created. The model was designed to rationalize the choices available when choosing the sales approaches. The relationship between sales approaches and results highlights the need for estimating qualitative variables, such as consumers, because they directly determine the company’s quantitative performance by purchasing the product offered by the company. The theoretical model helps systematically see the whole complex assessment process and, in each case, depending on the purpose of the assessment, to choose the methods which will let achieve the best results of the evaluation, at the same time allowing the company an opportunity to choose the best selling approach that would meet their expectations. It is necessary to pay attention to the fact that evaluation is a continuous process, so after the results of the evaluation of the chosen sales approach are received, it is necessary to return to the decision-making process and evaluate if the originally set goal was reached.
Conceptuación y Medición de la Agresividad: Validación de una Escala
Authors: Bouquet Escobedo Geraldine Stephanie , García Méndez Mirna , Díaz Loving Rolando , Rivera Aragón Sofía
Published: March 2019

El objetivo de esta investigación fue construir una escala de agresividad confiable y culturalmente relevante para adultos mexicanos. Se elaboraron 96 reactivos en escala Likert a partir de indicadores obtenidos en un estudio preliminar y de planteamientos teóricos. Participaron voluntarios de la Ciudad de México. Se obtuvieron cinco factores que agrupan 25 reactivos que explican el 61.59 % de la varianza, α=0.92. En otro estudio, se realizó un análisis factorial confirmatorio que mostró índices de ajuste adecuados. Posteriormente, se obtuvieron correlaciones entre la personalidad y la agresividad. Los resultados muestran que los factores extroversión, afabilidad, responsabilidad y apertura se asocian negativamente a la agresividad; mientras que el neuroticismo se asocia positivamente. Respecto a las diferencias por sexo, los resultados indican que los hombres muestran niveles más elevados de reactividad y las mujeres de frustración. Se concluye que la escala es un instrumento válido y confiable que permite reconocer diferencias entre los cinco grandes factores de personalidad, así como en hombres y mujeres.
Construction of exact solutions and analysis of stability of complex systems by reduction to ordinary differential equations with power nonlinearities
Authors: Kosov Alexander A. , Semenov Eduard I.
Published: March 2019

Complex systems described by nonlinear partial differential equations of parabolic type or large-scale systems of ordinary differential equations with switching right-side are considered. The reduction method is applied to the corresponding problem for the system of ordinary differential equations without switching. A parametric family of time-periodic and anisotropic on spatial variables exact solutions of the reaction-diffusion system is constructed. The stability conditions of a large-scale system with switching are obtained, which consist in checking the stability of the reduced system without switching. The conditions for the existence of the first integrals for the reduced system of ordinary differential equations expressed by a combination of power and logarithmic functions are found. For the cases of two-dimensional and three-dimensional reduced systems, these conditions are written in the form of polynomial equations relating the system parameters.
Genotyping of four loci in Hungarian Yellow and broiler chickens
Authors: Szalai Klaudia , Tempfli Károly , Lencsés-Varga Erika , Bali Papp Ágnes
Published: March 2019

Traditional selection has led to remarkable differences in allele frequencies among various chicken breeds. Indigenous and broiler-type chicken populations were genotyped for polymorphisms in thyroid hormone responsive Spot14α, prolactin (PRL), IGF-binding protein 2 (IGFBP2), and somatostatin (SST) genes in order to determine potential utilisation type-associated allele frequencies. Significant (P < 0.05) differences were detected between Hungarian Yellow and broiler populations for Spot14α, PRL, and IGFBP2 allele frequencies, whereas the same SST allele (A) was fixed in both groups. In this study, the most significant associations (P < 0.05) were found between the IGFBP2 genotypes and the measured traits (body weight, carcass weight, breast muscle weight with or without skin, breast muscle weight as a percentage of carcass weight) in the broiler population. The results can be applied for the evaluation of polymorphism effects in the analysed populations; however, contradictory allele effects in different breeds and hybrids indicate the need for cautious marker utilisation in selection programmes.
Epidemiology of human trichinellosis in Vojvodina province, Serbia, from 2005 to 2016
Authors: Petrović Jelena , Grgić Živoslav , Prodanov Radulović Jasna , Ratajac Radomir , Urošević Miroslav , Pustahija Tatjana , Medić Snežana
Published: March 2019

Trichinellosis is one of the most important foodborne diseases in the Eastern European countries. The main objective of this study was to investigate the epidemiological patterns of trichinellosis outbreaks that occurred between 2005 and 2016 in Vojvodina, a northern province of the Republic of Serbia. The average incidence was 3.5 per 100,000 inhabitants. A total of 828 people acquired the infection. The disease occurred in all age groups, slightly more often in males, and quite frequently in a severe form considering the high share of hospitalised patients and the fatal outcome rate (41.6 ± 31.1% and 0.4%, respectively). Trichinella spiralis was confirmed as the causative agent in eight outbreaks. The outbreaks usually occurred among family members due to the consumption of pork or traditional pork products from not tested backyard pigs. Veterinary control measures and the education of consumers and farmers should be implemented to control this zoonotic disease.
Effects of Tris (hydroxymethyl) aminomethane on the quality of frozen-thawed boar spermatozoa
Authors: Namula Zhao , Tanihara Fuminori , Wittayarat Manita , Hirata Maki , Nguyen Nhien Thi , Hirano Takayuki , Le Quynh Anh , Nii Masahiro , Otoi Takeshige
Published: March 2019

Tris (hydroxymethyl) aminomethane (Tris) has been used as a pH regulator for buffering the pH of dilution extenders for boar semen, such as the Modena extender. The purpose of the present study was to assess the effects of Tris supplementation at different concentrations (0, 8, 24 and 72 μM) into the freezing extender on the quality and fertilising capacity of frozen-thawed boar spermatozoa. The results showed that the supplementation of 24 μM of Tris gave significantly higher percentages of sperm viability and plasma membrane integrity than those of the control group at any time point of assessment (0 h and 3 h post-thawing) (P < 0.05). However, there were no significant differences in the acrosome integrity parameter among the groups. Higher percentages of sperm motility were observed in the spermatozoa cryopreserved with 24 μM of Tris compared to the control groups when the samples were analysed 0 h after thawing (P < 0.05). However, an increase of the Tris concentration to 72 μM did not enhance the sperm motility parameters. The total numbers of fertilised oocytes and blastocysts obtained with spermatozoa frozen with 24 μM Tris were significantly higher than those of the control group without Tris (P < 0.05). In conclusion, the supplementation of 24 μM Tris into the freezing extender contributes to a better boar sperm quality and fertilising capacity after the process of freezing and thawing.
First identification of porcine parvovirus 3 in a wild boar in Italy by viral metagenomics – Short communication
Authors: Amoroso Maria Grazia , Cerutti Francesco , D’Alessio Nicola , Lucibelli Maria Gabriella , Cerrone Anna , Acutis Pier Luigi , Galiero Giorgio , Fusco Giovanna , Peletto Simone
Published: March 2019

Metagenomic analysis revealed the presence of porcine parvovirus 3 (PPV3) in the pool of the internal organs of a wild boar found dead in Southern Italy. Phylogenetic analysis based on the complete coding sequences showed that the newly detected virus is most closely related to those found also in wild boars in Romania during 2010–2011. Even though the death could not be associated with this virus, PPV3 could have contributed to lowering the host’s immunological defences.
Frequency of diarrhoea-associated viruses in swine of various ages in Hungary
Authors: Valkó Anna , Marosi András , Cságola Attila , Farkas Rózsa , Rónai Zsuzsanna , Dán Ádám
Published: March 2019

Enteric viral diseases of swine are one of the most frequent disorders causing huge economic losses in pork production. After the reappearance of an emerging enteropathogen, porcine epidemic diarrhoea virus (PEDV) in Hungary in 2016, an extensive survey was initiated in an attempt to identify diarrhoea-related porcine viruses, including adeno-, astro-, boca-, calici-, circo-, corona-, kobu-, rota- and Torque teno viruses. A total of 384 faecal samples collected during a twoyear period from diarrhoeic and asymptomatic pigs of various ages in 17 farms were screened by conventional and real-time PCR methods. Half of the samples contained at least one examined virus with the dominance of kobuvirus (55.1%) followed by bocaviruses (33.2%) and rotavirus groups A and C together (20.9%), while coronaviruses including PEDV were not found in this set of samples. Statistical analysis showed a highly significant difference (P < 0.0001) in the frequency of single infections compared to mixed ones with the exception of weaned pigs, in which group additionally most viruses were detected. The results of this study suggest that the complexity of this disease may vary with age, which makes the prevention of diarrhoea a challenge, especially in weaned pigs.
First molecular detection of Apis mellifera filamentous virus in honey bees (Apis mellifera) in Hungary
Authors: Zana Brigitta , Geiger Lili , Kepner Anett , Földes Fanni , Urbán Péter , Herczeg Róbert , Kemenesi Gábor , Jakab Ferenc
Published: March 2019

Western honey bees (Apis mellifera) are important pollinators in the ecosystem and also play a crucial economic role in the honey industry. During the last decades, a continuous decay was registered in honey bee populations worldwide, including Hungary. In our study, we used metagenomic approaches and conventional PCR screening on healthy and winter mortality affected colonies from multiple sites in Hungary. The major goal was to discover presumed bee pathogens with viral metagenomic experiments and gain prevalence and distribution data by targeted PCR screening. We examined 664 honey bee samples that had been collected during winter mortality from three seemingly healthy colonies and from one colony infested heavily by the parasitic mite Varroa destructor in 2016 and 2017. The subsequent PCR screening of honey bee samples revealed the abundant presence of Apis mellifera filamentous virus (AmFV) for the first time in Central Europe. Based on phylogeny reconstruction, the newly-detected virus was found to be most closely related to a Chinese AmFV strain. More sequence data from multiple countries would be needed for studying the detailed phylogeographical patterns and worldwide spreading process of AmFV. Here we report the prevalent presence of this virus in Hungarian honey bee colonies.
On some topological properties of intuitionistic $2$-fuzzy $n$-normed linear spaces
Authors: KOČİNAC Ljubiša D. R. , KHAN Vakeel Ahmad , ALSHLOOL K.m.a.s. , ALTAF H.
Published: March 2019

Motivated by the notion of $n$-norm due to Gähler, in this article we define the concept of intuitionistic $2$-fuzzy $n$-normed space in general setting of $t$-norm as a generalization of intuitionistic fuzzy normed space  in the sense of Bag and Samanta. Further we define the notion of $\alpha$-$n$-norm corresponding to intuitionistic $2$-fuzzy $n$-norm. In addition, we discuss some basic properties of convergence and completeness for intuitionistic $2$-fuzzy $n$-normed spaces.
Iniciativas de Judicialização de Saúde no Brasil: Revisão Integrativa
Authors: Karen Fonseca Gonçalves da Silva  , Bruna Sordi Carrara  , Carla Aparecida Arena Ventura
Published: March 2019

Trata-se de revisão integrativa da literatura a respeito da judicialização da saúde no contexto brasileiro. Os objetivos foram identificar, analisar e sintetizar as evidências científicas disponíveis na literatura sobre as iniciativas de judicialização de saúde no Brasil. A busca dos artigos foi realizada nas bases de dados SCOPUS, SCIELO e LILACS, com estudos produzidos entre 2015 e 2018 e que tratassem sobre a judicialização da saúde no Brasil. Foram selecionados 29 artigos, dos quais 15 investigaram ações judiciais de saúde, e em 14 a iniciativa mais presente foi para obtenção de medicamentos. Foi observado que as despesas com essas ações são elevadas, o que leva à discussão sobre os altos gastos para ações individuais em detrimento à saúde coletiva. Foram apontados métodos alternativos às ações, como a mediação.
Homicídios e Acidentes de Crianças e Adolescentes: Análise de 2.462 Necropsias Médico-Legais
Authors: Leonardo Santos Bordoni  , Ana Clara Loureiro Gomes Marçoni  , Ana Paula Ribeiro Reis  , Camila Miguel Vieira  , Laura Moraes da Silva  , Mariana Rodrigues Tolentino  , Tiago Ribeiro Ferreira  , Polyanna Helena Coelho Bordoni
Published: March 2019

Mortes de crianças e adolescentes (CA) por causas externas são um importante problema mundial de saúde pública. Para uma melhor compreensão epidemiológica destes óbitos este estudo analisou laudos necroscópicos forenses de CA vítimas alegadas de acidentes e homicídios no período de 2006 a 2012 periciadas no Instituto Médico Legal de Belo Horizonte. Os homicídios compreenderam 65% dos 2.462 laudos de menores de 18 anos estudados. O trauma penetrante (“tiros” e “facadas”) foi mais prevalente nos homicídios (93%) enquanto o não penetrante prevaleceu nos acidentes (99%) (p
The Study of Middle Bronze Age Interments at Khanghah Gilavan: Tentative Results
Authors: Rezalou R. , Ayremlou Y. , Hariri N. , Eisvand S. F.
Published: March 2019

We give a detailed description of burials 14 and 24, typical of the Khanghah Gilavan cemetery, discovered in 2006 near Khalkhal, in the Ardabil Province, northwestern Iran. Parallels to the fi nds are discussed, mostly suggesting the Middle Bronze Age, although similar handmade vessels, hairpins, and daggers had been common in the region since the Early Bronze Age. The most illustrative examples are Nakhchivan-type vessels, the two handles of which are decorated with buttons. The burials indicate cultural changes over the Early and Middle Bronze Ages, despite the continuity of the ceramic manufacturing tradition.
The Xiongnu Gold from Noin-Ula (Mongolia)
Authors: Polosmak N. V. , Shatskaya S. S. , Zadorozhnyy M. V. , Kundo L. P. , Karpova E. V.
Published: March 2019

This article presents the results of interdisciplinary studies of gold artifacts from the elite Xiongnu burials at Noin-Ula (Noyon Uul, Mongolia, early 1st millennium AD), excavated by the Russian-Mongolian expedition in 2006–2012. Using scanning electron microscopy, atomic absorption spectroscopy, and inductively coupled plasma mass spectrometry, 17 artifacts were analyzed. These include ornaments from coffi ns and clothes, made by Chinese artisans. Results suggest that they were all made of native gold, similar to that from the known deposits of Mongolia in terms of elemental composition (for comparison, we used an electronic database relating to 3338 samples of Mongolian native gold). Results of statistical tests suggest that placer deposits were the most probable source of the gold. The results do not contradict the idea that Chinese artisans used Mongolian gold. During the Han era, the Xiongnu could have been among their principal providers. The relationships between the two empires and peoples were always benefi cial for the Xiongnu. Enjoying the numerous achievements of the Han civilization, they offered too little in return. One of the ways the Han dynasty could have benefi ted from their tumultuous neighbors was to receive native gold from them.
Geophysical Studies at the Horogoru Fortified Settlement in South Korea
Authors: Stoyakin M. A. , Kyujin Park
Published: March 2019

The results of prospection studies at the medieval site Horogoru, in the Gyeonggi-do Province of South Korea, are described. Using ground-penetrating radar, the defense wall, built of tamped earth and masonry, was reconstructed. The analyses of GPR images and 3D-models of the wall were confi rmed and supplemented by archaeological excavations. Prospection studies in the central part of the site have enabled us to assess tentatively the thickness of the habitation layer and its preservation. Structures associated with various archaeological cultures were analyzed. The results of excavations demonstrated a relative reliability of GPR, which had revealed anomalies at various depths. However, an accurate and complete assessment of the outlines of most structures proved impossible, owing to repeated medieval rebuilding, peculiar accumulation processes, and modern disruption. The GPR analysis of the anomalies indicated several stages of habitation. Early features, dating to the Koguryo period (400–700 AD), include a reservoir and a well, and next to these, heaps of roof tiles. Late features, dating to the Koryo stage (1000–1200 AD), include seven buildings, a stone pavement, and pits with roof tiles. Overall, the results demonstrate the effi ciency of geophysical methods for the assessment of the site’s structure and of the preservation of its cultural layers.
The 18th-Century Udmurt Women’s Outfits Depicted in J.P. Falk’s Book: Interpretation and Attribution
Authors: Nechvaloda E. E.
Published: March 2019

This study describes three engravings in the book by Academician Johan Peter Falk, showing Udmurt women in traditional outfi ts. Falk headed one of the most important expeditions of the 18th century, sponsored by the Russian Academy of Sciences. According to the fi gure captions, the women are Votyak, Bashkir, and Mishar, respectively; but ethnographic data suggest that two of these attributions are wrong. On the basis of comparison of the women’s outfi ts to those drawn by members of other 18th-century expeditions and of late 19th to early 20th-century ethnographic sources, relating to the composition of outfi ts, their construction, decoration, and ornaments, all the three women are Udmurt. The “Votyak” outfi t matches that of the southern Udmurt, the allegedly Mishar woman is central Udmurt, and the one said to be Bashkir is northern Udmurt. The accuracy of detail allows us to specify not only the ethnicity of the women, but their social status as well. The so-called “Votyak” and “Bashkir” outfi ts are those worn by married women, and that of the alleged “Mishar” is a girl’s dress. Generally, accurate representations, such as those illustrating the proceedings of the 18th-century expeditions from the Academy of Sciences, are a valuable and underexplored source of information.
Long-Bone Growth in the Bronze Age Skeletal Population of Gonur-Depe, Turkmenistan
Authors: Kufterin V. V.
Published: March 2019

This article presents some results of the analysis of long-bone growth rate in the sub-adult skeletal population from Gonur-Depe — a Bronze Age proto-urban center in Turkmenistan, the Bactria-Margiana Archaeological Complex. The sample includes 130 skeletons of sub-adults (735 skeletal elements) from burials in the “ruins” of the palace-temple ensemble, excavated in 2010–2015. The results indicate a signifi cant retardation of long-bone growth relative to modern standards. The individual variation is considerable. The retardation is maximal in the leg bones (especially femur and fi bula), and minimal in the forearm bones. The latter fact is confi rmed by the sub-adult to adult bone length ratio. The smallest lag in growth rates is observed in children aged from birth to 2–3 years. This was apparently due not only to optimal nutrition (breast-feeding), but also to a more stable genetic determination of growth during this period. The lag is greater in age cohorts showing stress markers, such as porotic hyperostosis and enamel hypoplasia. Retardation of skeletal maturity in this group is interpreted not as a symptom of maladaptation, but as a result of a complex process of adapting to the totality of environmental factors. The comparison of the paleodemographic, paleopathological, and “paleoauxological” data confi rms that the ancient population of the Murghab oasis was well adapted to the environment.
PREOPERATIVE MANAGEMENT OF PATIENTS WITH CARDIOVASCULAR DISEASES FOR ELECTIVE CANCER SURGERY
Authors: Sumin A. N.
Published: March 2019

Significant progress in the diagnosis and treatment of cancer resulted in a marked improvement in the survival of these patients. Declining mortality in acute cardiovascular diseases is accompanied by an increase in the proportion of patients with chronic cardiovascular pathology. Both trends resulted in a growing cohort of patients with concomitant oncology and cardiovascular disease, given rise to cardiooncology, a rapidly growing field. Cardio-oncology incudes a variety of clinical issues, particularly preoperative assessment of patients for cancer surgery. However, this section has been recently neglected in the recent guidelines. This review focuses on the preoperative management of patients with cardiovascular diseases for elective cancer surgeries. It reports the existing algorithm of assessing the risk of cardiac events in non-cardiac surgeries relatively to cancer patients. Current international and national guidelines were published in 2014 and, therefore, do not contain the latest evidences. Thus, this review summarizes all recent data and provides a modified and simplified preoperative management strategy for cancer patients. In particular, surgical risk assessment should be comprehensive, taking into account the complexity of the surgical procedures and the severity of comorbidity. The review discusses specific risk assessment scales proposed for different groups of cancer patients (for example, the ThRCRI scale in surgeries for non-small cell lung cancer). In addition, it contains various options for assessing the functional status of patients (stress tests, including spiroergometry, DASI index, assessment tables). Current recommendations on additional screening and preventive treatment of patients are summarized and addressed to the healthcare specialists and researchers studying perioperative risk assessment in cancer surgery.
ROLE OF RISK FACTORS FOR ARTERIAL HYPERTENSION IN PREGNANT WOMEN
Authors: Bichan N. A. , Rublevskaya A. S. , Vlasenko A. E. , Trofimenko N. A. , Kriulkina O. I.
Published: March 2019

Aim.To assess risk factors for arterial hypertension in pregnant women.

Methods.The prevalence of risk factors for arterial hypertension (AH) was estimated in 240 pregnant women with arterial hypertension (AH) and 126 healthy pregnant women. Women with symptomatic or gestational hypertension or diabetes mellitus were excluded from the study. The following AH risk factors were assessed: age, family history, smoking, overweight/obesity, and excessive salt intake. Odds ratios were calculated utilizing stepwise logistic regression.

Results.Pregnant women ≥32 years of age had 1.33-fold higher risk of AH in comparison with those <32 years of age. Hypertensive status of both parents or one of them was associated with 1.8- and 1.67-fold higher risk of AH as compared to patients without family history of AH. Smoking, overweight, and obesity increased risk of AH by a factor of 1.83, 1.74, and 2.24, respectively. Combination of age ≥32 years with obesity, family history of AH or smoking status further augmented risk of AH (2.46-, 2.18 or 2.14-fold, respectively) as compared to healthy pregnant women. Likewise, combination of AH family history with overweight or obesity resulted in 2.9- and 3.0-fold higher risk of AH. Combination of smoking with family history of AH, overweight, and obesity increased risk of AH by a factor of 2.95, 3.61, and 4.65, respectively. Amount of salt intake did not differ in pregnant women with and without AH.

Conclusion.The estimated risk factors for AH are significant in pregnant women. Age over 32 years was associated with 1.33 OR for AH, family history with 1.8 OR, smoking with 1.83 OR, overweight with 1.7 OR, whereas obesity increased 2.24-fold odds for AH. Obesity and family history increased 2.9-fold odds for AH, whereas smoking and family history were associated with 3-fold increased odds for AH and combined with obesity up to 4.6-fold increased odds.
SEASONAL INCIDENCE OF ACUTE CORONARY ACCIDENTS IN THE CLIMATE OF WESTERN SIBERIA. POPULATION RESEARCH
Authors: Okrugin S. A. , Repin A. N.
Published: March 2019

Aim. To determine seasonal patterns in the incidence of acute myocardial infarction (AMI) and sudden cardiac death (SCD) among the population of Tomsk city in the period from 2006 to 2015.

Methods.Data were obtained from the WHO project “Acute Myocardial Infarction Register”. 9060 cases, including 8383 (92.5%) – AMI and 677 (7.5%) – SCD, were registered within the 10-year follow-up among the inhabitants of Tomsk aged over 20 years old. The weather data were taken from the Tomsk branch of the West Siberian Federal Service for Hydrometeorology and Environmental Monitoring. V.I. Rusanov`s classification was used to identify the days with the contrast weather change.

Results.The highest incidence of acute coronary accidents was registered in January with the 11.7% increase the annual average, the lowest incidence - in November with the 7.8% decrease the annual average. Similarly, the highest incidence of MI was registered in January (+10.5%), and the lowest in November (-7.7%). The highest incidence of SCD was registered in January (+ 28.6%), while the lowest - in October (-6.1%). The months associated with increase in the rate of acute coronary accidents in general and MI and SCD have been selected. In 2006 it was October, in 2009 – April, in 2011 – March and in 2012 – January. These months had a large number of days with contrasting weather changes.

Conclusion.The most unfavorable months in the period from 2006 to 2015 associated with the development of acute coronary accidents were January and May. Days with contrasting weather changes contributed to the increase in the incidence of acute coronary accidents. The determined patterns should be taken into account when planning the delivery of care to patients with acute coronary pathology.
FEDERAL STATE BUDGETARY INSTITUTION “RESEARCH INSTITUTE FOR COMPLEX ISSUES OF CARDIOVASCULAR DISEASES”
Authors: Tarasov R. S. , Ivanov S. V. , Ganyukov V. I. , Sotnikov A. V. , Kozyrin K. A. , Danilovich A. I. , Barbarash L. S.
Published: March 2019

Aim. To estimate long-terms results of incomplete revascularization with the internal thoracic artery to the left anterior descending anastomosis performed during mammary-coronary bypass grafting (MCBG) in 228 patients with stable coronary artery disease using the single-center registry database.

Methods.All patients were enrolled into 2 groups. Group 1 consisted of patients with residual SYNTAX score ≤8 (group SYNTAX ≤8, n = 75), Group 2 with residual SYNTAX score >8 (group SYNTAX ≥9, n = 153).

Results.The reasons for the incomplete revascularization were: (1) small diameter of the distal segment of the coronary arteries in 52 (23%) patients, (2) calcification and transmural scar of the myocardium in 18 (8%) patients, (3) severe concomitant pathology in 33 (14%) patients, (4) danger and / or inability to place proximal anastomosis on the ascending aorta in 35 (16%) cases, (5) coronary artery hypoplasia in 11 (5%) patients, (6) unfit grafts for shunting in 6 (2%) patients, (7) technical difficulties in visualization of coronary arteries on the posterior and lateral walls due to Dressler's syndrome in 9 (4%) patients. (8) Incomplete revascularization was considered reasonable in 64 (28%) cases due to the number of causes. The three-year all-cause mortality was 4% in the group of SYNTAX ≤8 versus 3.9% in the SYNTAX group ≥9, P = 0.7, similarly to the cardiac death – 2.7% in the group of SYNTAX ≤8 versus 3.3% in the group SYNTAX ≥9, P = 0.9. The need for repeat coronary revascularization was the same in both groups (P = 0.4). The groups did not differ in the number of the combined endpoint (8% in the group of SYNTAX ≤8 versus 6.5% in the group SYNTAX ≥9, (P = 0.9).

Conclusion.The study demonstrated that the results of incomplete revascularization with LIMA to LAD do not depend on the residual SYNTAX score.
Possibilities of the use of shear wave elastography of the liver in pregnant women infected with viral hepatitis B and C
Authors: Saryeva E G
Published: March 2019

Aim. To determine the diagnostic possibilities of using liver shear wave elastography in pregnant women with hepatitis B and C viral infection. Methods. The study included 87 women with hepatitis B and C viral infections admitted to the Center of Clinical Medicine №1 and Educational and Therapeutic Clinic of Azerbaijan Medical University (basis of the department of obstetrics and gynecology 2 of Azerbaijan Medical University) in 2016 to 2017 aged 18-45 (average age 31.4±7.1 years), and 50 uninfected women with physiological pregnancy matched by the age (average age 30.6±6.8 years). Infected women were divided into two groups: 70 pregnant women (group 1) and 17 women (group 2), who were non-pregnant at the time of the study (average age 29.8±7.2 and 30.9±6.7 years, respectively). Women with physiological course of pregnancy were included into group 3 (average age 30.6±6.8 years). Groups of pregnant patients were matched by age, gestation age and parity (p ˃0.05). All patients underwent clinical and biochemical analyses and shear wave elastography of the liver. The obtained data were processed using the methods of variation statistics with calculation of mean and standard error (M±m), Mann-Whitney U-test, Spearman's rank correlation coefficient. Results. In 52.9±6% of the examined pregnant women with viral hepatitis, hepatitis B was identified, in 47.1±6% - hepatitis C. According to the results of shear wave elastography, the average density of the liver in these patients was 7.2±1.0 kPa. An increase in liver density in pregnant women with viral hepatitis was not accompanied by changes in the size of the liver (only 1 patient had hepatomegaly). In 71.4±5.4% of the patients, F1 degree was revealed, in 20.0±4.8% - F2, in 5.7±2.8% - F3, in 2.9±2.0% - F4. İn comparison with infected patients without pregnancy, pregnant women with viral hepatitis B and C had more severe degree of fibrosis [F1 was significantly less frequent (p ˂0.05), and F2 was significantly more frequent (p ˂0.05)], and also had F4 degree, which was not observed in non-pregnant. In infected pregnant women, there was a positive correlation between liver echogenicity and density of its tissues (p=0.495; p <0.001). Conclusion. In pregnant women with hepatitis B and C viral infection, the use of shear wave elastography allows detecting various degrees of liver fibrosis by a non-invasive method in the early stages, even in the absence of marked clinical and laboratory changes.
Anomia no patíbulo: desaparições da legalidade dramática em “O verdugo”, de Hilda Hilst
Authors: Delmanto Ivan
Published: March 2019

O ensaio analisa a peça de Hilda Hilst, “O verdugo”, e procura revelar, nas modificações realizadas pela autora sobre os modelos originais do drama moderno e do teatro épico europeus, que a obra pode ser melhor compreendida a partir do conceito de “profecia”, de Walter Benjamin. O texto de Hilda figura, no contexto histórico do regime militar brasileiro, uma antecipação das estratégias de violência estatal que marcariam um trauma coletivo na formação histórica do país. Tais estratégias do regime fizeram conviver a dominação legal com práticas de tortura e de desaparecimento de opositores, e estão sedimentadas no tecido formal da dramaturgia de “O verdugo”.
O duplo pacto representativo: porosidades e enganos do real em Tijuana, de Gabino Rodríguez
Authors: Costa Júlia Morena
Published: March 2019

Este ensaio objetiva analisar a peça Tijuana, do coletivo “Lagartijas tiradas al sol”, baseado no romance colombiano, 6 meses con el salario mínimo, de Andrés Solano. A obra teatral propõe a discussão acerca das vidas possíveis no norte mexicano, a partir da experiência do ator Gabino Rodríguez, convertido durante seis meses em Santiago Ramírez, habitante de Tijuana, sob condições específicas que o afastaram do seu mundo habitual enquanto trabalhava nas maquiladoras mexicanas. A partir da análise dos textos dramático e espetacular, objetiva-se discutir os porosos limites entre o real e o ficcional, através dos efeitos de real provocados nos textos, ao utilizar o princípio da experiência pessoal compartilhada com o leitor/público.
Reading Audiences, Reading Materials: Reception in Tanya Saracho’s El Nogalar
Authors: Huerta Melissa
Published: March 2019

Tanya Saracho’s El Nogalar (2011), adaptation of Anton Chekhov’s The Cherry Orchard, recreates the Russian’s play social context in 21st century Mexican society, going through the awakening of the violence that dominates the U.S./Mexico border. The focus of this study is the audience’s response to El Nogalar premier at the Goodman’s theater. Such analysis is conducted by reading the paratextual elements, such as the program and related material found online. By analyzing the script, playbill, reviews, and the study guide, this study calls for an increased use of supplemental material in order to critically think about audience reception. The complexity of the play, as an adaptation alone, is enough to justify the need for more knowledge of non-traditional methods to approach the text and the surrounding material, including reviews, playbills and educational guides. These elements not only provide new insight into interpreting the performance and dramatic text, but they also offer ways to approach audience reception beyond the review.
Tempo e drama: do presente absoluto à simultaneidade de temporalidades
Authors: Nascimento Rodrigo Alves do , Gomide Bruno Barreto
Published: March 2019

Na virada do século XIX para o século XX emergiu um tipo de dramaturgia na qual a experiência temporal dos personagens passava a ser elemento temático decisivo. Do mesmo modo, o próprio tempo se tornava um problema formal, visível e produtivo. Tal processo é patente nas peças de Ibsen, Maeterlinck e Strindberg, que romperam com a tradição neoclássica, então pautada por uma temporalidade discreta, quase invisível, em que o drama e a própria representação cênica se fechavam à experiência de um presente absoluto. Dentro desse impulso de renovação, as peças de Tchékhov – em especial As Três Irmãs – tiveram papel crucial. Como veremos, elas acomodaram na tessitura dramática uma simultaneidade de temporalidades, levaram o realismo ao seu limite e desestabilizaram a própria relação entre o tempo do texto e o tempo da cena.
Desire, desire, desire: uma paródia de Christopher Durang ao teatro estadunidense
Authors: Flores Fulvio Torres , Grazioli Fabiano Tadeu
Published: March 2019

A peça em um ato Desire, desire, desire (1995), de Christopher Durang, parodia uma série de peças do teatro estadunidense, algumas já consideradas clássicas como Um bonde chamado desejo e Gata em telhado de zinco quente, de Tennessee Williams, e outras bastante conhecidas, como O homem de gelo, de Eugene O’Neill, Boa noite, mãe, de Marsha Norman, O sucesso a qualquer preço, de David Mamet, e Meu amigo Harvey, de Mary Chase. Todas essas peças foram adaptadas para o cinema e fazem parte, em menor ou maior medida, do repertório cultural da população. Com base em textos que tratam de intertextualidade e paródia, procuramos demonstrar como Durang cria a sua paródia e como sua peça responde a discussões pertinentes no final do século XX, que não estavam postas ou eram apenas incipientes nas décadas em que tais textos foram criados.
Ressonâncias da tradição
Authors: Pelinser André Tessaro
Published: March 2019

Resumo: Este artigo examina as obras de João Guimarães Rosa, Mário de Andrade e João Simões Lopes Neto com o objetivo de verificar em que medida pontos de contato identificados na ficção desses autores promovem rearranjos na série literária brasileira. O estudo parte da noção de tradição literária, tal qual formulada por T. S. Eliot e Jorge Luis Borges, e, em seguida, procura mapear a ocorrência de ressonâncias das principais obras de Mário de Andrade e Simões Lopes Neto na literatura de Guimarães Rosa. Assim procedendo, pretende averiguar como a obra de Guimarães Rosa ressignifica os textos de Mário de Andrade e Simões Lopes Neto, renovando sua legibilidade e modificando sua posição no campo literário.Palavras-chave: Guimarães Rosa; Mário de Andrade; Simões Lopes Neto; tradição literária.Abstract: We discuss João Guimarães Rosa’s, Mário de Andrade’s, and João Simões Lopes Neto’s works, with the purpose of verifying to what extent contact points identified in these authors’ fiction promote readjustments in the Brazilian literary series. The reflection is based on the literary tradition notion, as formulated by T. S. Eliot and Jorge Luis Borges, and subsequently aims at mapping the occurrence of resonances of Mário de Andrade and Simões Lopes Neto works in Guimarães Rosa’s literature. By doing so, the study intends to examine how Guimarães Rosa’s work resignifies Mário de Andrade and Simões Lopes Neto texts, renewing their legibility and modifying their position in the literary field.Keywords: Guimarães Rosa; Mário de Andrade; Simões Lopes Neto; literary tradition.
Apresentação
Authors: Soares Claudia Campos , Menezes Roniere , Rowland Clara , Finazzi-Agró Ettore
Published: March 2019

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Periodic solutions of Euler-Lagrange equations with sublinear potentials in an Orlicz-Sobolev space setting
Authors: Acinas Sonia , Mazzone Fernando
Published: March 2019

In this paper, we obtain existence results of periodic solutions of hamiltonian systems in the Orlicz-Sobolev space \(W^1L^\Phi([0,T])\). We employ the direct method of calculus of variations and we consider  a potential  function \(F\) satisfying the inequality \(|\nabla F(t,x)|\leq b_1(t) \Phi_0'(|x|)+b_2(t)\), with \(b_1, b_2\in L^1\) and  certain \(N\)-functions \(\Phi_0\).
The generalized Day norm. Part II. Applications
Authors: Budzyńska Monika , Grzesik Aleksandra , Kot Mariola
Published: March 2019

In this paper we prove that for each \(1< p, \tilde{p} < \infty\), the Banach space \((l^{\tilde{p}}, \left\|\cdot\right\|_{\tilde{p}})\) can be equivalently renormed in such a way that  the Banach space \((l^{\tilde{p}},\left\|\cdot\right\|_{L,\alpha,\beta,p,\tilde{p}})\) is LUR and has a diametrically complete set with empty interior. This result extends the Maluta theorem about existence of such a set in \(l^2\) with the Day norm. We also show that the Banach space \((l^{\tilde{p}},\left\|\cdot\right\|_{L,\alpha,\beta,p,\tilde{p}})\) has the weak fixed point property for nonexpansive mappings.
Properties of modulus of monotonicity and Opial property in direct sums
Authors: Markowicz Joanna , Prus Stanisław
Published: March 2019

We give an example of a Banach lattice with a non-convex modulus of monotonicity, which disproves a claim made in the literature. Results on preservation of the non-strict Opial property and Opial property under passing to general direct sums of Banach spaces are established.
On a two-parameter generalization of Jacobsthal numbers and its graph interpretation
Authors: Bród Dorota
Published: March 2019

In this paper we introduce a two-parameter generalization of the classical Jacobsthal numbers ((s,p)-Jacobsthal numbers). We present some properties of the presented sequence, among others Binet’s formula, Cassini’s identity, the generating function. Moreover, we give a graph interpretation of (s,p)-Jacobsthal numbers, related to independence in graphs.