bluuebunny/crossref_metadata_2025 huggingface dataset:
The impact of TQM and green innovation on corporate sustainability: the mediating role of green supply chain management
Authors: Makhlouf Hamdi , Chatti Nejmeddine , Lakhal Lassaad
Published: April 2023

Purpose

This empirical study aims to investigate the direct and indirect effects among total quality management (TQM), green innovation (GI), corporate sustainability (CS) and green supply chain management (GSCM).

Design/methodology/approach

The authors collected data from 120 respondents in the French manufacturing industry using survey questionnaires. The authors used the partial least squares structural equation path modeling (PLS-SEM) to examine the hypotheses of the study.

Findings

Results indicate that TQM and GI influences CS, TQM and GI influences GSCM and GSCM influences CS. Furthermore, results show that GSCM mediates the influence of TQM and GI on CS.

Research limitations/implications

This study helps managers in achieving their sustainability goals. The findings may help managers and practitioners to understand how TQM and GI influences GSCMP and CS, as well as assist manufacturers in identifying practices that need improvement.

Originality/value

This study offers additional value and shows the importance of TQM, GI and GSCM practices on corporate sustainability and the key role played by GSCMP to ensure CS.
The influence of the socioeconomic and politico-administrative environment on the extent of compliance with IPSAS in developing countries
Authors: Mnif Yosra , Gafsi Yosra
Published: April 2023

Purpose

This paper investigates to what extent public sector entities (PSEs) in developing countries (DCs) are compliant with IPSAS and examines the impact of the socioeconomic and politico-administrative environment on this compliance during the period 2015–2018.

Design/methodology/approach

This research develops a self-constructed checklist consisting of 116 disclosure items from five accrual-based IPSAS (IPSASs, 1, 2, 3, 14 and 24) and applies panel regressions for a sample of 500 entity-year observations of 125 PSEs.

Findings

The study results show a high level of disparity in the degree of compliance with IPSAS amongst DCs' governments, with an overall average level of 61%. They reveal that compliance with IPSAS is positively influenced by the level of citizen wealth, government political culture (degree of government openness) and the quality of public administration, whereas jurisdiction size, government financial condition and political competition are non-significant factors.

Practical implications

This research provides researchers and practitioners with a comprehensive framework for understanding the extent of New Public Management reforms in DCs with a focus on International Public Sector Accounting Standards implementation. It might assist policymakers in their accounting strategies and might be a signal for DCs with low compliance to tap lessons from governments with successful experience of IPSAS adoption.

Originality/value

Focusing on DCs' context, this paper brings new insights into the analysis of socioeconomic and politico-administrative incentives for government compliance with IPSAS. It is the first to investigate the impact of citizen wealth and political competition on IPSAS disclosures.
Impact of exchange rate fluctuations on US stock market returns
Authors: Bhargava Vivek , Konku Daniel
Published: April 2023

Purpose

The authors analyze the relationship between exchange rate fluctuations of a number of major currencies and its impact on US stock market returns, as proxied by the S&P 500. Many studies have explored this topic since the early 1970s with varied results and with no evidence that clearly explains the relationship between exchange rates and stock market returns. This study takes a different look at this hypothesis and investigates the pairwise relationship between various exchange rates and the United States stock market returns (S&P 500 INDEX) from January 2000 to December 2019.

Design/methodology/approach

The authors test the data for unit roots using Phillip-Perron method. They use Johansen cointegration model to determine whether returns on S&P 500 are integrated with S&P 500. They use the VAR/VECM analysis to test whether there are any interdependencies between exchange rates and stock market return. Finally, they use various GARCH models, including the EGARCH and TGARCH models, to determine whether there exist volatility spillovers from exchange rate fluctuations in various markets to the volatility in the US stock market.

Findings

Using GARCH modeling, the authors find volatility in Australian dollar, Canadian dollar and the euro impact market return, and the volatility of Australian dollars and euro spills over to the volatility of S&P 500. They also find that the spillover is asymmetric for Australian dollars.

Research limitations/implications

One of the limitations could be that the authors use different bivariate GARCH models rather than the MV-GARCH models. For future project(s), they plan to do this analysis from the perspective of a European Union or a British investor and use returns in those markets to see the impact of exchange rates on those markets. It would be interesting to know how the relationship will change during periods of financial crises. This could be achieved by employing structural break methodology.

Originality/value

Many studies have explored the relation between stock market returns and exchange rates since the early 1970s with varied results and with no evidence that clearly explains the relationship between exchange rates and stock market returns. This paper contributes by adding to the existing literature on impact of exchange rate on stock returns and by providing a detailed and different empirical analysis to support the results.
Interpretations of business continuity management in the light of COVID-19
Authors: Sawalha Ihab Hanna , Anchor John R.
Published: April 2023

Purpose

This study aims to investigate how organizations from different sectors interpret the meaning of business continuity management (BCM) in the light of the COVID-19 pandemic.

Design/methodology/approach

A survey was conducted to capture the views of organizations across five different sectors. The sample consisted of ten senior managers; two from the banking sector; two from the supply chain sector (agricultural and food supply chains); two from the tourism sector; two from the services sector; and two from the higher education sector. An interviewer-administered questionnaire was used to collect the data. One manager from each sector represented a local business/enterprise and the other represented an international business/enterprise.

Findings

It was found that different organizations/businesses understood BCM differently. Therefore, a variety of interpretations have been obtained.

Practical implications

This study sheds light on how different organizations understand BCM in times of crisis, such as the COVID-19 pandemic. By understanding the different interpretations, it becomes clearer whether or not these organizations have applicable business continuity plans in place.

Originality/value

This is the first study to investigate the different interpretations of the meaning of BCM across different business sectors. The majority of the existing studies on BCM discuss the process from the perspective of a single business or sector. The study was conducted during the COVID-19 pandemic, a period that witnessed prolonged and critical disruptions facing almost all businesses and organizations and which threatened the survival of some of them.
Human resource management in public transports: organizational typologies and research actions
Authors: Marino Alfonso , Pariso Paolo
Published: April 2023

Purpose

Studying bus local public transport in 20 Italian provincial capitals, the present paper aims to identify organizational factors to assess different modes of service managerial steering.

Design/methodology/approach

Starting from bureaucratic theory, the paper analyzes four different modes of managerial steering in a regression model that accounts for several variables to assess the quality of Italian bus local public service transport.

Findings

The research shows that a network managerial structure performs significantly better than any other type. The 20 provincial capitals are homogeneous in relation to the variables considered. Italian bus local public transport is managed by bureaucratic public organizations. Adhocracy, as opposed to machine bureaucracy, seems to be the more effective mode of managerial steering for sector specific aspects in different capitals, despite that, network managerial structure – associated adhocracy – is used only in five capitals (main cities).

Originality/value

The paper highlights that the dichotomy between machine bureaucracy versus adhocracy shows interesting considerations related to different mode to management of Italian bus local public service transport.
Association between neighborhood socioeconomic status and mechanical thrombectomy for acute ischemic stroke: A nationwide multilevel observational study
Authors: Kim Ki Hong , Ro Young Sun , Shin Sang Do , Kim Seong Jung
Published: April 2023

Objective

Acute ischemic stroke is a major health burden worldwide and mechanical thrombectomy is the treatment of choice for large‐vessel occlusion stroke. This study aimed to evaluate the association between neighborhood socioeconomic status (SES) and the likelihood of receiving mechanical thrombectomy in patients with acute ischemic stroke.

Methods

A nationwide cross‐sectional study was conducted using the National Emergency Department Information System database. Patients who were diagnosed with ischemic stroke in the emergency department (ED) within 24 h of symptom onset between 2018 and 2021 were included. The neighborhood SES index was measured at the county level using property tax per capita, education level, and the proportions of single families and single‐parent households. The study population was divided into quartiles based on the neighborhood SES index. The study outcome was mechanical thrombectomy. Multilevel multivariable logistic regression was performed. An interaction analysis between mental status at the ED triage and neighborhood SES was also performed.

Results

Among the 196,007 patients, 8968 (4.6%) underwent mechanical thrombectomy. Compared with the affluent group, the deprived‐middle and deprived groups were less likely to receive mechanical thrombectomy; the adjusted ORs (95% CIs) were 1.00 (0.92–1.09), 0.82 (0.74–0.91), and 0.82 (0.72–0.93) for the affluent‐middle, deprived‐middle, and deprived groups, respectively. Altered mental status at the ED triage strengthened the association between neighborhood SES and the likelihood of receiving mechanical thrombectomy (adjusted ORs [95% CIs] 0.85 [0.81–0.89] for the affluent‐middle to deprived‐middle group and 0.66 [0.65–0.66] for deprived groups, p‐value for interaction < 0.05).

Conclusions

For patients diagnosed with acute ischemic stroke at the ED, low neighborhood SES is associated with low odds of receiving mechanical thrombectomy. Public health strategies should be developed to resolve these disparities and to decrease the health care burden of acute ischemic stroke.
Effects of impermeable and semipermeable glove materials on resolution of inflammation and epidermal barrier impairment after experimental skin irritation
Authors: Heichel Theres , Brans Richard , John Swen M. , Nienhaus Albert , Nordheider Kathrin , Wilke Annika , Sonsmann Flora K.
Published: April 2023

Background

Semipermeable membranes might be suitable for glove liners or comfort gloves in individuals with irritant contact dermatitis (ICD).

Objectives

To evaluate the effects of different glove materials on inflammation and epidermal barrier impairment after experimental skin irritation.

Methods

Nine test areas on the volar forearms of 24 healthy volunteers were irritated with sodium lauryl sulfate (1%) and afterward covered for 6 days (6 or 8 h/day) with semipermeable Sympatex (SYM), vinyl (OCC), combinations of vinyl with Sympatex (SYM/OCC) or cotton (COT/OCC), or left uncovered (CON). Up to day 10, measurements of transepidermal water loss (TEWL), erythema (a*), skin humidity (SH) and visual scoring (VS) were applied.

Results

No significant differences in skin parameters were found between COT/OCC and SYM/OCC as well as between each of the combinations and CON. SYM, COT/OCC and SYM/OCC led to better results for most skin parameters than OCC alone.

Conclusions

Occlusive material has a negative impact on skin barrier recovery and inflammation after skin irritation whereas SYM is not inferior to uncovered areas indicating good tolerability. Altogether, the data suggest that SYM is a useful alternative to COT as material for glove liners and comfort gloves in ICD patients.
The importance of wetland habitat area for waterbird species‐richness
Authors: Cerda‐Peña Carol , Rau Jaime R.
Published: April 2023

The area of habitat patches is a significant factor when determining species‐richness in any given habitat. However, this area effect is not the same for every taxonomic group and can change if is considered together with other habitat variables. The main objective of this study was to identify the importance of wetland area for waterbird species‐richness when it is considered in conjunction with other habitat variables. Studies published in the Scopus and Web of Science databases in marine/coastal and inland wetlands were reviewed. A vote‐counting approach was conducted to evaluate how many studies include area as a major variable, and a meta‐analysis was performed to measure the effect size of the relationship between area and species‐richness. Area was a significant predictor of waterbird species‐richness in most of the studies (28 of 40 studies, 70%) as assessed by the vote‐counting approach, and the mean effect size was high (r = 0.81, n = 1 studies) in the meta‐analysis. Few studies reported the shape of the relationship between habitat area and species‐richness, but most reported a positive correlation. Although the species–area relationship is widely recognized, our review shows that an important proportion of studies (30%) also found that other habitat variables were significant variables when they were considered together with habitat area. Consequently, in the case of wetlands, habitat area should be considered in conservation, but not as the only measure of management and restoration if the objective is to conserve waterbird biodiversity by improving species‐richness.
Can diabetes influence fetal thymus size during pregnancy?
Authors: Sinaci Selcan , Sahin Dilek
Published: April 2023

Objective

The aim of the study was to evaluate fetal thymus size by sonography in diabetic pregnancies and its relationship with diabetes type.

Methods

In this prospectively designed case–control study, fetal thymus transverse diameter and circumference of the fetal thymus were measured. Also, TTR (thymic‐thoracic ratio) was assessed in 288 healthy and 105 diabetic pregnancies. Patients were divided into subgroups as diet‐controlled gestational diabetes (GDMA1, n = 40), insulin‐dependent (GDMA2, n = 42), and pregestational diabetes mellitus (PGDM, n = 23). GDM was diagnosed between 24 and 28 weeks of gestation with a 75 g oral glucose tolerance test. Measurements were compared to the healthy control group. Pairwise comparisons with Bonferroni correction determined which type of diabetes was independently associated with a small fetal thymus.

Results

All 3 maternal diabetes categories had smaller fetal thymus size than controls (p < 0.05). TTR were lowest in PGDM (p < 0.05).

Conclusion

Gestational diabetes is associated with smaller fetal thymus size. Pregestational diabetes may be associated with a smaller fetal thymus compared to diet‐controlled GDM. Also, the thymus size may be even smaller in those with poor blood glucose regulation.
Neoehrlichia mikurensis—An emerging opportunistic tick‐borne infection in immunosuppressed patients
Authors: Gynthersen Rosa M. M. , Stensvold Christen Rune , Nielsen Signe Ledou , Møller Holger Jon , Nielsen Henrik Vedel , Lebech Anne‐Mette , Christensen Jeppe Romme , Mens Helene , El Fassi Daniel
Published: April 2023

Background

Neoehrlichia mikurensis (N. mikurensis) is a newly discovered tick‐borne pathogen that can inflict life‐threatening illness in immunocompromised patients. N. mikurensis infection is only detectable by polymerase chain reaction (PCR)‐based methodologies. We describe three distinct clinical manifestations of N. mikurensis infection (neoehrlichiosis) in Danish patients receiving B‐lymphocyte‐depleting therapy, rituximab, for underlying hematological, rheumatological, or neurological disorders. All three patients went through a protracted pre‐diagnostic period.

Methods

N. mikurensis DNA was detected and confirmed using two methods. Blood was tested by specific real‐time PCR targeting the groEL gene and by 16S and 18S profiling followed by sequencing. Bone marrow was analyzed by 16S and 18S profiling.

Results

N. mikurensis was detected in blood samples in all three cases and in bone marrow from one of the three. The severity of the symptoms ranged from prolonged fever lasting more than 6 months to life‐threatening hyperinflammation in the form of hemophagocytic lymphohistiocytosis (HLH). Interestingly, all patients presented with splenomegaly and two with hepatomegaly. After starting doxycycline therapy, symptoms were relieved within a few days, and biochemistry and organomegaly quickly normalized.

Conclusion

We present three Danish patients recognized by the same clinician over a period of 6 months, strongly suggesting that many cases are going unrecognized. Second, we describe the first case of N. mikurensis‐induced HLH and emphasize the potential severity of undetected neoehrlichiosis.
Epidemiology and risk factors for mammary tumours in female cats
Authors: Pickard Price P. , Stell A. , O'Neill D. , Church D. , Brodbelt D.
Published: April 2023

Objectives

This study aimed to estimate the incidence and risk factors for mammary tumours in female cats attending UK primary‐care practices. The study hypothesised that middle‐aged, intact and certain breeds are associated with increased mammary tumour risk.

Materials and Methods

A case–control study design identified mammary tumour cases by assessment of electronic patient records, nested within a denominator population of 259,869 female cats attending 886 primary‐care VetCompass participating veterinary practices in the UK in 2016.

Results

From 2858 potential mammary tumour cases identified within the denominator, 270 cats met the case definition, giving an incidence risk of 104 per 100,000 (0.104%, 95% confidence interval 0.092 to 0.117%) during 2016. In the risk factor analysis increasing age, purebred compared to crossbred and veterinary group were associated with increased odds of mammary tumour. Median survival after the diagnosis of mammary tumour cats was 18.7 months.

Clinical Significance

The current study provides an updated estimate of the incidence of mammary cancer in cats seen in primary care veterinary practice in the UK with increasing risk seen in older cats and with purebred status. This study can aid veterinary surgeons to identify cats at greater risk of mammary tumour and advise on survival after diagnosis.
Identification of a novel sporadic U2HR pathogenic variant in a patient with Marie Unna hereditary hypotrichosis
Authors: Braun Tatjana , Wehner Maria , Teichler Anne , Betz Regina C. , Hoeger Peter H.
Published: April 2023

Marie Unna hereditary hypotrichosis (MUHH) is a rare autosomal dominant hair loss disorder characterized by coarse, wiry, and twisted hair developing during early childhood, and followed by progressive hair loss with puberty. We report a sporadic case of a 4‐year‐old boy with clinical features suggestive of MUHH, in whom we identified the new pathogenic variant c.67C>T; p.(Gln23*) in U2HR. This finding extends the known spectrum of U2HR variants underlying MUHH and increases genetic information for further genotype–phenotype correlation.
Complete denture rehabilitation for a patient with Parkinson's disease using clinical strategies: A case report
Authors: Ribeiro Anne Kaline Claudino , Lemos Luisa Madeira , de Aquino Luana Maria Martins , Costa Rayanna Thayse Florêncio , de Moraes Sandra Lúcia Dantas , Carreiro Adriana da Fonte Porto
Published: April 2023

Objective

To present clinical strategies for prosthetic rehabilitation with complete dentures (CDs) of a Parkinson's disease patient.

Case report

An 82‐year‐old patient sought the Department of Dentistry at UFRN, reporting retention dissatisfaction and hamper to the mandibular CD adaptation. Patient‐reported a dry mouth sensation, and exhibited disordered mandibular movements, tremors, and resorbed mandibular ridge. Aiming retention and stability, double molding with zinc enolic oxide impression paste, neutral zone technique, and non‐anatomic teeth were proposed as clinical strategies. At delivery, identification and relief in the supercompression areas were performed to facilitate the acceptance and use of the new dentures.

Conclusion

The strategies promoted patient satisfaction regarding retention, stability, and comfort. This treatment may be considered for the rehabilitation of Parkinson's disease patients, favoring the adaptation process.
Glycosmis kanburiensis: A new species of Rutaceae from Thailand
Authors: AIYAKOOL Wichai , VAJRODAYA Srunya
Published: April 2023

Glycosmis kanburiensis (Rutaceae) from Kanchanaburi Province, southwestern Thailand is described as a new species. It is similar to G. esquirolii (H. Lév.) Tanaka in its dendriform habit, terminal inflorescences, and large leaflets, but several easily recognizable differences in floral features, including triangular sepals with rust-colored indumentum (vs. broadly ovate villose sepals), globose, glabrous (vs. subglobose, villosus) ovary, cylindrical and attenuate (vs. stout) style, and ellipsoid (vs. globose) fruit. A taxonomic description, illustration, photographs, geographical distribution, ecological data, and conservation status are provided.
Comparative genomics of Viola selkirkii and V. ulleungdoensis (Violaceae)
Authors: GO Ah-reum , YOO Ki-Oug
Published: April 2023

Chloroplast genomes of two morphologically similar species, Viola selkirkii and V. ulleungdoensis, were compared. For this comparison, three individuals of V. selkirkiii from Ulleung-do Island (UE), Jeju-do Island (JJ), and Hwacheon-gun (HC) and one of V. ulleungdoensis from UE were collected. According to chloroplast genome sequencing of V. selkirkiii and V. ulleungdoensis, their genomes were found to contain 156,774–157,454 and 157,575 bp, respectively, and a total of 111 genes. In the comparison of the three V. selkirkiii individuals, V. selkirkiii obtained in UE was distinguished from those of the other regions of HC and JJ, and in the comparison of the three V. selkirkiii individuals and one V. ulleungdoensis individual, V. selkirkiii obtained from UE and V. ulleungdoensis were distinguished from the species in the other regions. In addition, a phylogenetic analysis revealed that 32 taxa of Viola formed a monophyletic group (bootstrap support [BS] = 100). The four Viola individuals used in this study (three V. selkirkiii and one V. ulleungdoensis) formed a monophyletic group (BS = 100), which was further divided into two subclades. One subclade comprised V. selkirkiii found in UE and V. ulleungdoensis, whereas the other subclade comprised V. selkirkiii found in HC and JJ. These results support the view of prior studies that V. selkirkiii growing in UE and V. ulleungdoensis are the same species.
Adaptive Radioresistance of Enterohemorrhagic Escherichia coli O157:H7 Results in Genomic Loss of Shiga Toxin-Encoding Prophages
Authors: Gaougaou Ghizlane , Vincent Antony T. , Krylova Kateryna , Habouria Hajer , Bessaiah Hicham , Baraketi Amina , Veyrier Frédéric J. , Dozois Charles M. , Déziel Eric , Lacroix Monique
Published: April 2023

Gamma irradiation of food products can provide an effective means of eliminating bacterial pathogens such as enterohemorrhagic
Escherichia coli
(EHEC) O157:H7, a significant foodborne pathogen that can cause severe disease due to the production of Stx. To decipher the mechanisms of adaptive resistance of the O157:H7 strain EDL933, we evolved clones of this bacterium resistant to a lethal dose of gamma irradiation by repeatedly exposing bacterial cells to irradiation following a growth restoration over six successive passages.
Molecular Diagnosis of Leishmaniasis in Spain: Development and Validation of Ready-To-Use Gel-Form Nested and Real-Time PCRs To Detect
Leishmania
spp.
Authors: Chicharro Carmen , Nieto Javier , Miguelañez Silvia , Garcia Emilia , Ortega Sheila , Peña Ana , Rubio Jose Miguel , Flores-Chavez Maria
Published: April 2023

Although the gold standard for diagnosis of leishmaniasis is the microscopic observation of amastigotes, molecular techniques are becoming a cost-efficient alternative. Currently, PCR is a routine resource that is used in many reference microbiology laboratories.
Supplemental Material: Estimating paleotidal constituents from Pliocene “tidal gauges”—an example from the paleo-Orinoco Delta, Trinidad
Authors: Chen Si , et al.
Published: April 2023

Supplemental Text: Supplemental Material Captions. Table S1: List of the most common tidal constituents, with period and rotational speed in solar hours. Figure S1: Daily tidal heights and summary of the tidal constituents most responsible for those tides from two tidal reference stations. Figure S2: Listing of tidal gauge stations and tidal statistics from the Gulf of Carpentaria in Australia. Figure S3: Amplitude ratio (F) equation and tide types.
BET 2: Missed diagnosis of ischaemic stroke in the emergency department
Authors: Shake Alisha , Oostema Adam , Jones Jeffrey
Published: April 2023

A short cut review was carried out to establish the rate and clinical characteristics of missed diagnosis of acute ischaemic stroke in the emergency department (ED). Two papers presented the best evidence to answer the clinical question. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of these papers are shown in table 1. It is concluded that acute ischaemic stroke is missed in approximately 9%–14% of patients with this diagnosis who present to the ED. This is especially true in patients presenting with non-specific complaints such as dizziness, nausea/vomiting or altered level of consciousness.
Vietnamese Sentiment Analysis: An Overview and Comparative Study of Fine-tuning Pretrained Language Models
Authors: Van Thin Dang , Hao Duong Ngoc , Nguyen Ngan Luu-Thuy
Published: April 2023

Sentiment Analysis (SA) is one of the most active research areas in the Natural Language Processing (NLP) field due to its potential for business and society. With the development of language representation models, numerous methods have shown promising efficiency in fine-tuning pre-trained language models in NLP downstream tasks. For Vietnamese, many available pre-trained language models were also released, including the monolingual and multilingual language models. Unfortunately, all of these models were trained on different architectures, pre-trained data, and pre-processing steps; consequently, fine-tuning these models can be expected to yield different effectiveness. In addition, there is no study focusing on evaluating the performance of these models on the same datasets for the SA task up to now. This article presents a fine-tuning approach to investigate the performance of different pre-trained language models for the Vietnamese SA task. The experimental results show the superior performance of the monolingual PhoBERT model and ViT5 model in comparison with previous studies and provide new state-of-the-art performances on five benchmark Vietnamese SA datasets. To the best of our knowledge, our study is the first attempt to investigate the performance of fine-tuning Transformer-based models on five datasets with different domains and sizes for the Vietnamese SA task.
Optimal Intensity Measures for Probabilistic Seismic Stability Assessment of Large Open-Pit Mine Slopes under Different Mining Depths
Authors: Che Wei , Chang Pengfei , Wang Wenhao
Published: April 2023

The dynamic stability of slopes is the key to ensure the safety of a large open-pit mine during and after a strong earthquake. This study was mainly focused on the identification of optimal intensity measures (IMs) for the probabilistic seismic stability assessment of large open-pit mine slopes within the framework of performance-based earthquake engineering (PBEE). To this end, four open-pit slopes with different mining depths were constructed as the reference cases for the numerical investigation. The randomness of input ground motions and the uncertainty of material properties of the slopes were also considered. A total of 96 ground-motion records and 29 common IMs were selected for testing. By a series of nonlinear time-history analyses, the probabilistic seismic demand models (PSDMs) between the minimum factor of safety (FOS) of slopes and all considered IMs were developed. The optimal IMs with respect to FOS were identified based on the evaluation of five criteria: correlation, efficiency, practicality, proficiency, and sufficiency. The impacts on seismic fragility and FOS response hazard of the slopes were discussed when using different IMs. The results reveal that sustained maximum velocity (SMV) and velocity spectrum intensity (VSI) are recognized as the optimal IM for a mining depth of 50 m and 100 m, respectively. However, Housner intensity (HI) is observed to have the best predictability for both the mining depths of 200 m and 300 m. Moreover, for the three most commonly used IMs, peak ground velocity (PGV) is superior to peak ground acceleration (PGA) and spectral acceleration at first mode period (Sa (T1)) for different mining depths. Finally, based on the evaluations of seismic fragility and FOS response hazard, the uncertainty of seismic stability prediction of open-pit slopes can be greatly reduced when using a more appropriate or optimal IM.
Perception of Heaviness Induced by Sensorimotor Incongruence Is Associated with Pain Prognosis: A Pilot Study
Authors: Matsuda Soichiro , Osumi Michihiro
Published: April 2023

Background. Patients with chronic musculoskeletal pain experience not only pain but also abnormal body perception. Such abnormal body perception has been reported to be caused by incongruence between motor intentions and sensory feedback (i.e., sensorimotor incongruence). However, the influence of abnormal body perception with sensorimotor incongruence on pain prognosis in musculoskeletal pain patients has not been investigated. Objective. We aimed at clarifying the influence of abnormal body perception on pain prognosis using an experimental procedure for inducing sensorimotor incongruence in patients with musculoskeletal pain. Methods. We recruited 18 patients within 2 months after limb fracture or ligament injury. In the experiment, patients sat with the intact upper or lower limb reflected in a large mirror aligned with the sagittal plane. A motor task was performed for 20 seconds in each of the congruent and incongruent conditions. In the congruent condition, patients were asked to perform flexion-extension movements with the intact and affected limbs in-phase, while observing the intact limb in the mirror. In the incongruent condition, patients were asked to perform flexion-extension movements antiphase, while observing the intact limb in the mirror. After performing the congruent and incongruent conditions, patients were asked to complete a questionnaire about abnormal body perception. These procedures were conducted within 2 months after the fracture (first), 2 weeks after the first measurement (second), and 4 weeks (third) after the first measurement. Results. Pain, heaviness, and peculiarity were more likely to be experienced in incongruent conditions. Additionally, structural equation modeling indicated that heaviness at the first time point predicted the pain intensity at the second and third time points. Conclusions. Heaviness caused by sensorimotor incongruence may predict pain prognosis in patients with musculoskeletal pain after one month.
Supplementary Table S8 from Antisense RNAs Influence Promoter Usage of Their Counterpart Sense Genes in Cancer
Authors: Bellido Molias Fernando , Sim Andre , Leong Ka Wai , An Omer , Song Yangyang , Ng Vanessa Hui En , Lim Max Wei Jie , Ying Chen , Teo Jasmin Xin Jia , Göke Jonathan , Chen Leilei
Published: April 2023

List of 521 unique ncNATs expressed in non-tumor samples of one or multiple cancer/tissue types from TCGA and GTEx.
Video A, B and C from FILIP1L Loss Is a Driver of Aggressive Mucinous Colorectal Adenocarcinoma and Mediates Cytokinesis Defects through PFDN1
Authors: Kwon Mijung , Rubio Genesaret , Nolan Nicholas , Auteri Peter , Volmar Jean Arly , Adem Asha , Javidian Parisa , Zhou Zhongren , Verzi Michael P. , Pine Sharon R. , Libutti Steven K.
Published: April 2023

PowerPoint file containing embedded videos.
TableS1 from Modeling High-Grade Serous Ovarian Carcinoma Using a Combination of In Vivo Fallopian Tube Electroporation and CRISPR-Cas9–Mediated Genome Editing
Authors: Teng Katie , Ford Matthew J. , Harwalkar Keerthana , Li YuQi , Pacis Alain S. , Farnell David , Yamanaka Nobuko , Wang Yu-Chang , Badescu Dunarel , Ton Nu Tuyet Nhung , Ragoussis Jiannis , Huntsman David G. , Arseneau Jocelyne , Yamanaka Yojiro
Published: April 2023

Supplementary Table
Supplementary Figure1 from Modeling High-Grade Serous Ovarian Carcinoma Using a Combination of In Vivo Fallopian Tube Electroporation and CRISPR-Cas9–Mediated Genome Editing
Authors: Teng Katie , Ford Matthew J. , Harwalkar Keerthana , Li YuQi , Pacis Alain S. , Farnell David , Yamanaka Nobuko , Wang Yu-Chang , Badescu Dunarel , Ton Nu Tuyet Nhung , Ragoussis Jiannis , Huntsman David G. , Arseneau Jocelyne , Yamanaka Yojiro
Published: April 2023

Supplementary Figure1
Supplementary Data from SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia
Authors: Chambers Courtney , Cermakova Katerina , Chan Yuen San , Kurtz Kristen , Wohlan Katharina , Lewis Andrew Henry , Wang Christiana , Pham Anh , Dejmek Milan , Sala Michal , Loeza Cabrera Mario , Aguilar Rogelio , Nencka Radim , Lacorazza H. Daniel , Rau Rachel E. , Hodges H. Courtney
Published: April 2023

Supplementary Materials
Suppl. Figure S9 from ROS Induction Targets Persister Cancer Cells with Low Metabolic Activity in NRAS-Mutated Melanoma
Authors: Eichhoff Ossia M. , Stoffel Corinne I. , Käsler Jan , Briker Luzia , Turko Patrick , Karsai Gergely , Zila Nina , Paulitschke Verena , Cheng Phil F. , Leitner Alexander , Bileck Andrea , Zamboni Nicola , Irmisch Anja , Balazs Zsolt , Tastanova Aizhan , Pascoal Susana , Johansen Pål , Wegmann Rebekka , Mena Julien , Othman Alaa , Viswanathan Vasanthi S. , Wenzina Judith , Aloia Andrea , Saltari Annalisa , Dzung Andreas , Krauthammer Michael , Schreiber Stuart L. , Hornemann Thorsten , Distel Martin , Snijder Berend , Dummer Reinhard , Levesque Mitchell P.
Published: April 2023

S9: Treatment of binimetinib-sensitive melanoma cell lines with PPP inhibitor
Suppl. Figure S2 from ROS Induction Targets Persister Cancer Cells with Low Metabolic Activity in NRAS-Mutated Melanoma
Authors: Eichhoff Ossia M. , Stoffel Corinne I. , Käsler Jan , Briker Luzia , Turko Patrick , Karsai Gergely , Zila Nina , Paulitschke Verena , Cheng Phil F. , Leitner Alexander , Bileck Andrea , Zamboni Nicola , Irmisch Anja , Balazs Zsolt , Tastanova Aizhan , Pascoal Susana , Johansen Pål , Wegmann Rebekka , Mena Julien , Othman Alaa , Viswanathan Vasanthi S. , Wenzina Judith , Aloia Andrea , Saltari Annalisa , Dzung Andreas , Krauthammer Michael , Schreiber Stuart L. , Hornemann Thorsten , Distel Martin , Snijder Berend , Dummer Reinhard , Levesque Mitchell P.
Published: April 2023

S2: HPLC analysis of STO13881 and nNeocuproine showed overlapping profiles and confirmed STO13881 to be neocuproine (purchased from Sigma-Aldrich, Switzerland). High-performance liquid chromatography (HPLC) analysis was performed using the Zuürich functional genomic center.
Supplementary Data from A Systematic Review and Multilevel Regression Analysis Reveals the Comorbidity Prevalence in Cancer
Authors: Vrinzen Cilla E.J. , Delfgou Linn , Stadhouders Niek , Hermens Rosella P.M.G. , Merkx Matthias A.W. , Bloemendal Haiko J. , Jeurissen Patrick P.T.
Published: April 2023

Supplementary tables and figure
Supplementary Table S5 from PGC1α Degradation Suppresses Mitochondrial Biogenesis to Confer Radiation Resistance in Glioma
Authors: Zhao Mengjie , Li Yanhui , Lu Chenfei , Ding Fangshu , Xu Miao , Ge Xin , Li Mengdie , Wang Zhen , Yin Jianxing , Zhang Junxia , Wang Xiefeng , Ge Zehe , Xiao Hong , Xiao Yong , Liu Hongyi , Liu Wentao , Cao Yuandong , Wang Qianghu , You Yongping , Wang Xiuxing , Yang Kun , Shi Zhumei , Qian Xu
Published: April 2023

Table S5. GSVA scores for GBM cells
Supplementary Figures from PGC1α Degradation Suppresses Mitochondrial Biogenesis to Confer Radiation Resistance in Glioma
Authors: Zhao Mengjie , Li Yanhui , Lu Chenfei , Ding Fangshu , Xu Miao , Ge Xin , Li Mengdie , Wang Zhen , Yin Jianxing , Zhang Junxia , Wang Xiefeng , Ge Zehe , Xiao Hong , Xiao Yong , Liu Hongyi , Liu Wentao , Cao Yuandong , Wang Qianghu , You Yongping , Wang Xiuxing , Yang Kun , Shi Zhumei , Qian Xu
Published: April 2023

Supplementary Figures and Figure legends
S2 from TLE3 Sustains Luminal Breast Cancer Lineage Fidelity to Suppress Metastasis
Authors: Anstine Lindsey J. , Majmudar Parth R. , Aponte Amy , Singh Salendra , Zhao Ran , Weber-Bonk Kristen L. , Abdul-Karim Fadi W. , Valentine Mitchell , Seachrist Darcie D. , Grennel-Nickelson Katelyn E. , Cuellar-Vite Leslie , Sizemore Gina M. , Sizemore Steven T. , Webb Bryan M. , Thompson Cheryl L. , Keri Ruth A.
Published: April 2023

Supplemental Figure 2
Table S3 from Linking Physical Activity to Breast Cancer via Inflammation, Part 2: The Effect of Inflammation on Breast Cancer Risk
Authors: Lou Makayla W.C. , Drummond Ann E. , Swain Christopher T.V. , Milne Roger L. , English Dallas R. , Brown Kristy A. , van Roekel Eline H. , Skinner Tina L. , Moore Melissa M. , Gaunt Tom R. , Martin Richard M. , Lewis Sarah J. , Lynch Brigid M.
Published: April 2023

Supplementary Table 3 presents the risk of bias assessment, using the ROBINS-E
Figure S4D from Linking Physical Activity to Breast Cancer via Inflammation, Part 2: The Effect of Inflammation on Breast Cancer Risk
Authors: Lou Makayla W.C. , Drummond Ann E. , Swain Christopher T.V. , Milne Roger L. , English Dallas R. , Brown Kristy A. , van Roekel Eline H. , Skinner Tina L. , Moore Melissa M. , Gaunt Tom R. , Martin Richard M. , Lewis Sarah J. , Lynch Brigid M.
Published: April 2023

Supplementary Figure 4D presents the funnel plots from the meta-analysis of leptin and breast cancer risk
Figure S1C from Linking Physical Activity to Breast Cancer via Inflammation, Part 2: The Effect of Inflammation on Breast Cancer Risk
Authors: Lou Makayla W.C. , Drummond Ann E. , Swain Christopher T.V. , Milne Roger L. , English Dallas R. , Brown Kristy A. , van Roekel Eline H. , Skinner Tina L. , Moore Melissa M. , Gaunt Tom R. , Martin Richard M. , Lewis Sarah J. , Lynch Brigid M.
Published: April 2023

Supplementary Figure 1C present forest plots for CRP and breast cancer risk, excluding studies that had a moderate risk of bias
Figure S3 from High-Throughput Peptide Arrays Identify Potential Diagnostic Autoantibody Signatures in Early-Stage Lung Adenocarcinoma
Authors: Luo Rongrong , Zhong Pei , Li Xiying , Cai Juan , Tao Yimin , Xiong Bangzhu , Zheng Hancheng , Zhang Zhishang , Tang Le , Yao Jiarui , Li Yingrui , Shi Yuankai , Han Xiaohong
Published: April 2023

Figure S3. Autoantibodies differentially expressed in plasma samples from patients with Early-LUAD versus NHC. Each boxplot represents an individual peptide signature in the two sample sets.
Table S2 from Deep Transcriptome Profiling of Multiple Myeloma Using Quantitative Phenotypes
Authors: Griffin Rosalie , Hanson Heidi A. , Avery Brian J. , Madsen Michael J. , Sborov Douglas W. , Camp Nicola J.
Published: April 2023

Hazard ratios of high vs low risk of progression free survival.
Supplemental Methods from Deep Transcriptome Profiling of Multiple Myeloma Using Quantitative Phenotypes
Authors: Griffin Rosalie , Hanson Heidi A. , Avery Brian J. , Madsen Michael J. , Sborov Douglas W. , Camp Nicola J.
Published: April 2023

Expanded description of the SPECTRA approach.
Table S6C from Linking Physical Activity to Breast Cancer Risk via Inflammation, Part 1: The Effect of Physical Activity on Inflammation
Authors: Swain Christopher T.V. , Drummond Ann E. , Milne Roger L. , English Dallas R. , Brown Kristy A. , Lou Makayla W.C. , Boing Leonessa , Bageley Amy , Skinner Tina L. , van Roekel Eline H. , Moore Melissa M. , Gaunt Tom R. , Martin Richard M. , Lewis Sarah J. , Lynch Brigid M.
Published: April 2023

Supplementary Table 6C presents findings of individual non-randomised interventions
Table S2C from Linking Physical Activity to Breast Cancer Risk via Inflammation, Part 1: The Effect of Physical Activity on Inflammation
Authors: Swain Christopher T.V. , Drummond Ann E. , Milne Roger L. , English Dallas R. , Brown Kristy A. , Lou Makayla W.C. , Boing Leonessa , Bageley Amy , Skinner Tina L. , van Roekel Eline H. , Moore Melissa M. , Gaunt Tom R. , Martin Richard M. , Lewis Sarah J. , Lynch Brigid M.
Published: April 2023

Supplementary Table 2C presents the study characteristics for non-randomised interventions
Figure S1B from Linking Physical Activity to Breast Cancer Risk via Inflammation, Part 1: The Effect of Physical Activity on Inflammation
Authors: Swain Christopher T.V. , Drummond Ann E. , Milne Roger L. , English Dallas R. , Brown Kristy A. , Lou Makayla W.C. , Boing Leonessa , Bageley Amy , Skinner Tina L. , van Roekel Eline H. , Moore Melissa M. , Gaunt Tom R. , Martin Richard M. , Lewis Sarah J. , Lynch Brigid M.
Published: April 2023

Supplementary Figure 1B presents forest plots for physical activity and CRP, by exercise type
Table S8 from Diet Quality and All-Cause Mortality in Women with Breast Cancer from the Breast Cancer Family Registry
Authors: Haslam Danielle E. , John Esther M. , Knight Julia A. , Li Zhongyu , Buys Saundra S. , Andrulis Irene L. , Daly Mary B. , Genkinger Jeanine M. , Terry Mary Beth , Zhang Fang Fang
Published: April 2023

Table S8 Shows Hazard Ratios and 95% Confidence Intervals for Total Mortality in Women Diagnosed with Breast Cancer with or without Excluding People Reporting Post-Diagnosis Diet Less than 12 Month after Diagnosis
Table S3 from Diet Quality and All-Cause Mortality in Women with Breast Cancer from the Breast Cancer Family Registry
Authors: Haslam Danielle E. , John Esther M. , Knight Julia A. , Li Zhongyu , Buys Saundra S. , Andrulis Irene L. , Daly Mary B. , Genkinger Jeanine M. , Terry Mary Beth , Zhang Fang Fang
Published: April 2023

Table S3 Shows Hazard Ratios and 95% Confidence Intervals for All-Cause Mortality in Women Diagnosed with Breast Cancer (unrelated women)
Supplementary Table S3 from Neighborhood Socioeconomic Status and Racial and Ethnic Survival Disparities in Oral Cavity and Laryngeal Cancer
Authors: Liu Yupeng , Zhong Lydia , Puram Sidharth V. , Mazul Angela L.
Published: April 2023

Hazard ratios, 95% confidence intervals, and p-values of oral cavity and larynx cancer patients in a multivariable analysis.
Supplementary Table S1 from Neighborhood Socioeconomic Status and Racial and Ethnic Survival Disparities in Oral Cavity and Laryngeal Cancer
Authors: Liu Yupeng , Zhong Lydia , Puram Sidharth V. , Mazul Angela L.
Published: April 2023

Table summarizing 5-year overall survival rate of oral cavity cancer patients.
Supplementary Figure S3 from Neighborhood Socioeconomic Status and Racial and Ethnic Survival Disparities in Oral Cavity and Laryngeal Cancer
Authors: Liu Yupeng , Zhong Lydia , Puram Sidharth V. , Mazul Angela L.
Published: April 2023

Four KM curves depicting 5-year overall survival of oral cavity cancer patients in Asian subgroups.
Data from Linking Physical Activity to Breast Cancer via Inflammation, Part 2: The Effect of Inflammation on Breast Cancer Risk
Authors: Lou Makayla W.C. , Drummond Ann E. , Swain Christopher T.V. , Milne Roger L. , English Dallas R. , Brown Kristy A. , van Roekel Eline H. , Skinner Tina L. , Moore Melissa M. , Gaunt Tom R. , Martin Richard M. , Lewis Sarah J. , Lynch Brigid M.
Published: April 2023

Abstract
This review synthesized and appraised the evidence for an effect of inflammation on breast cancer risk. Systematic searches identified prospective cohort and Mendelian randomization studies relevant to this review. Meta-analysis of 13 biomarkers of inflammation were conducted to appraise the evidence for an effect breast cancer risk; we examined the dose–response of these associations. Risk of bias was evaluated using the ROBINS-E tool and the quality of evidence was appraised with Grading of Recommendations Assessment, Development, and Evaluation. Thirty-four observational studies and three Mendelian randomization studies were included. Meta-analysis suggested that women with the highest levels of C-reactive protein (CRP) had a higher risk of developing breast cancer [risk ratio (RR) = 1.13; 95% confidence interval (CI), 1.01–1.26] compared with women with the lowest levels. Women with highest levels of adipokines, particularly adiponectin (RR = 0.76; 95% CI, 0.61–0.91) had a reduced breast cancer risk, although this finding was not supported by Mendelian randomization analysis. There was little evidence of an effect of cytokines, including TNFα and IL6, on breast cancer risk. The quality of evidence for each biomarker ranged from very low to moderate. Beyond CRP, the published data do not clearly support the role of inflammation in the development of breast cancer.

See related article by XXXX et al., p. 000
Supplementary Table S6 from Randomized, Double-Blind, Placebo-Controlled Trial of MUC1 Peptide Vaccine for Prevention of Recurrent Colorectal Adenoma
Authors: Schoen Robert E. , Boardman Lisa A. , Cruz-Correa Marcia , Bansal Ajay , Kastenberg David , Hur Chin , Dzubinski Lynda , Kaufman Sharon F. , Rodriguez Luz M. , Richmond Ellen , Umar Asad , Szabo Eva , Salazar Andres , McKolanis John , Beatty Pamela , Pai Reetesh K. , Singhi Aatur D. , Jacqueline Camille M. , Bao Riuye , Diergaarde Brenda , McMurray Ryan P. , Strand Carrie , Foster Nathan R. , Zahrieh David M. , Limburg Paul J. , Finn Olivera J.
Published: April 2023

Background Information on Advanced Adenoma
Supplementary Table S4 from Randomized, Double-Blind, Placebo-Controlled Trial of MUC1 Peptide Vaccine for Prevention of Recurrent Colorectal Adenoma
Authors: Schoen Robert E. , Boardman Lisa A. , Cruz-Correa Marcia , Bansal Ajay , Kastenberg David , Hur Chin , Dzubinski Lynda , Kaufman Sharon F. , Rodriguez Luz M. , Richmond Ellen , Umar Asad , Szabo Eva , Salazar Andres , McKolanis John , Beatty Pamela , Pai Reetesh K. , Singhi Aatur D. , Jacqueline Camille M. , Bao Riuye , Diergaarde Brenda , McMurray Ryan P. , Strand Carrie , Foster Nathan R. , Zahrieh David M. , Limburg Paul J. , Finn Olivera J.
Published: April 2023

Adverse Events: Grade 2
Supplementary Methods S2 from Randomized, Double-Blind, Placebo-Controlled Trial of MUC1 Peptide Vaccine for Prevention of Recurrent Colorectal Adenoma
Authors: Schoen Robert E. , Boardman Lisa A. , Cruz-Correa Marcia , Bansal Ajay , Kastenberg David , Hur Chin , Dzubinski Lynda , Kaufman Sharon F. , Rodriguez Luz M. , Richmond Ellen , Umar Asad , Szabo Eva , Salazar Andres , McKolanis John , Beatty Pamela , Pai Reetesh K. , Singhi Aatur D. , Jacqueline Camille M. , Bao Riuye , Diergaarde Brenda , McMurray Ryan P. , Strand Carrie , Foster Nathan R. , Zahrieh David M. , Limburg Paul J. , Finn Olivera J.
Published: April 2023

supplementary methods: Detailed laboratory methods