bluuebunny/crossref_metadata_2025 huggingface dataset:
Major Regularities of Transformation of the Small Mammal Ovaries in Unfavourable Environmental Conditions: Ecological and Morphological Aspects
Authors: Blinova E. V. , Shevlyuk N. N.
Published: December 2021

The aim of the study was to determine the patterns of structural and functional organization of the ovaries of female small mammals inhabiting technogenically altered ecosystems.

Material and methods. We studied the ovaries of small mammal species belonging to the insectivore and rodent families (common shrew, field and pygmy wood mice, common and bank voles, mole vole, steppe pied) that live in anthropogenically altered ecosystems (zones of influence of ferrous and nonferrous metallurgy, as well as gas processing factory). The resulting material was processed using observational histological, histochemical, immunohistochemical and morphometric tests.

Results. The results obtained demonstrated that in technogenically altered ecosystems the intensified reproduction results in a complex of morphofunctional reactive and adaptive changes in the ovaries of females of the studied species. The size of the ovaries was reduced; the area of the cortical substance was reduced. In the cortex, there was revealed a decrease in the number of follicles varying over a wide range - from a moderate decrease to their almost complete absence. There was found a decrease in the area of the vessels of the microvasculature; this was one of the major reasons for the increased follicular atresia. In follicles of various types, there was an increase in the proportion of cells expressing the proapoptotic protein P53. A decrease in the number of follicles resulted in the connective tissue overgrowth. The presence of cysts lined with epithelium of various heights was revealed in the cortex and medulla.

 Conclusion. The results obtained evidence that in technogenically altered ecosystems a decreased ovarian reserve is observed in the ovaries of female small mammals; it is associated with a more rapid depletion of the follicle reserve in the cortex due to both - intensification of reproduction and more rapid death of follicles in unfavourable environmental conditions.
Somatotype as a Component of the Biological Determinant of Mental Health
Authors: Chevzhik Yu. V. , Shemyakov S. E. , Milushkina O. Yu. , Nikityuk D. B. , Klyueva L. A. , Vladimirova Ya. B.
Published: December 2021

The paper summarizes the results of the studies devoted to the impact of a person's constitutional features on his or her mental state. According to many anthropologists, human constitution is characterized not only by a specifics of metabolism level (muscle, fat and bone components of the body) and by a susceptibility to certain types of diseases, but also by psychophysiological features. Since biological health, including mental health, is generally determined by genetic and hereditary factors, the authors of the paper examine the possibility of considering the somatotype as a component of the biological determinant of mental health. To create the concept of a personalized approach that takes into account the relationship of somatotype and psychophysiological indicators in the educational process, the authors propose to conduct a study of the students' constitutional characteristics in combination with psychological testing.
O teatro com comunidade: uma proposta pedagógica
Authors: Rosa Maíra
Published: December 2021

Este artigo tem como objetivo compartilhar as formas de ensino aprendizagem em Teatro Comunitário realizadas no bairro Residencial 2000, periferia da cidade de Uberaba/MG, junto às crianças e adolescentes. A pergunta norteadora foi: Como o ensino de teatro dialoga de forma horizontal com tal comunidade? Desta forma, discorreremos sobre metodologias advindas do Teatro do Oprimido de Augusto Boal, dos ensinamentos de Paulo Freire e também das próprias formas e expressões culturais da juventude desta comunidade.
Innovations on rail freight market
Authors: Naletina Dora , Damić Mate
Published: December 2021

Ten years ago, the European Union recognized the importance of stopping further development of road freight transportation and the need for making rail freight a more prominent branch of industry. Rail transportation used to hold a more relevant position, but because of slow response to changes on the market and no investments in modernization, it now occupies only around 10% of the share in freight transportation in most EU member states. Most members have initiated the implementation of the restructuring and liberalization of rail market, with the aim of establishing a multimodal transportation network and reducing negative impact of road freight on the environment. The Croatian market is no exception, of course. It has liberalized the rail freight market since the Accession to the EU, while the rail passenger traffic is still monopolized by a company owned by the state. The Croatian national carrier HŽ Cargo has decided to face the competition by restructuring the current business and giving a sharper focus on innovation (intermodal terminals, RO-LA, and digitalization of business operations). The above-mentioned topics are analysed in the following chapter.
Individual Regulation of Legal Relationships in Science and Engineering in the Conditions of Digitalization: A Theoretical Legal Aspect
Authors:   Head of the Department of Theory and History of Law and State of the Kazan Branch of the Russian State University of Justice PhD (Law), Associate Professor, Gumerov Lenar A.
Published: December 2021

The author creates evidence-based knowledge about the essence of individual regulation of legal relations, revealing the features of this type of regulation in the scientific and technological sphere in the context of the digitalization of civil society. The increasing role of individual regulation is substantiated in connection with the openness of society, the existing processes of its self-organization, as well as the need for self-realization of individuals. It has been established that the development of individual regulation in the scientific and technological sphere is facilitated by the lack of proper legal regulation of new social relations. The article analyzes the existing approaches to individual regulation in legal science, identifies the differences between legal and individual regulation of legal relations. The theoretical debatable nature of the concept of «individual legal regulation» has been proved. Results of a research can be used in law-making activity, including in the process of interaction between civil society and the state, aimed at improving the legal regulation of the scientific and technological sphere, in the subsequent scientific research.
Constitutional Principles of Law as a Ground of the Civil Society (Based on Russian and Armenian Law)
Authors:   Associate Professor of the Department of Theory of State and Law, International and European Law of the Academy of the Federal Penitentiary Service of Russia Senior Research Scientist of the Research Center of the Nizhny Novgorod Institute of Management, Branch of the Russian Presidential Academy of National Economy and Public Administration PhD (Law), Associate Professor, Ilyukhina Vera A.
Published: December 2021

The article compares the constitutional principles of law of the Russian Federation and the Republic of Armenia. The author structures the material based on the classification of constitutional principles of law, within which the principles are divided into general legal, intersectoral and sectoral. The constitutional principles of law are considered as the foundation of civil society.
Ethnic and Race Problems in a Federal State (Based on the Results of the U.S. Presidential Campaign of 2020)
Authors:   Head of the Department of Theory of State and Law and Political Science of the Penza State University LL.D., Doctor of History, Professor, Salomatin Aleksey Yu. , Makeeva Natalya V. ,   Associate Professor of the Department of Theory of State and Law and Political Science of the Penza State University PhD (Law), Associate Professor
Published: December 2021

The United States, originally formed as a haven for immigrants of different ethnic and racial backgrounds, has felt the inefficiency of its famous «melting pot»since the beginning of the XXI century. In this ethnically-and racially-conflicted state, one of the long-standing problems was considered to be the problem of African-Americans, who after World War II dispersed outside the southern states. This problem was only partially solved, and the policy of positive discrimination in favor of blacks in recent years has become increasingly critical. At the same time, the country, in which the proportion of white citizens is sharply decreasing and the number of Spanish-speaking people and people of Asian origin is increasing, is experiencing an increasing cultural, civilizational and geographical split. During the 2020 presidential campaign, the United States faced not only an epidemic of coronavirus infection, but also unprecedented protest activity, which was a test for the outdated mechanism of this federal state. The domestic political crisis might have been averted or mitigated if the United States had had a more centralized model of federalism, which would have strengthened administrative coordination and allowed ethno-racial egoism to be contained within certain limits.
A Comparative Country Analysis of Legal and Management Bases of Regulation of Migration Processes
Authors:   Chief Research Scientist of the Department of Political Science of the Faculty of Social Sciences and Mass Communications of the Financial University under the Government of the Russian Federation Doctor of History, Galas Marina L.
Published: December 2021

Changes in the types of economic, political and legal behavior, social interests and forms of their protection in the modern world are connected, among other things, with migration processes. With economic, labour and demographic potential, migration carries social, political and other risks that are perceived with concern by the titular population and can lead to threats to public stability and national interests if the State does not take appropriate regulatory measures. Migration risks can be seen as a factor in the emergence of tension in the host society, as well as ethnic, religious, socio-economic conflict situations. On the other hand, migration processes have an impact on the social development of recipient states, reflected in the legal frameworks and management mechanisms of regulation of migration, labour market, employment, social sphere. «The Global Compact for Safe has been an important goal of the social adaptation of foreign nationals into the host society while creating favorable conditions for social harmony and promoting the integration of migrants. The article conducted a country comparative analysis of the legal and management frameworks for regulating migration processes in the main recipient states.
Synthesis of Geranyloxycoumarin Derivatives under Mild Conditions Using Cs2CO3
Authors: HWANG Sumi , ROH Eonjoo
Published: December 2021

In this study, the synthesis of various geranyloxycoumarin derivatives from hydroxycoumarin was obtained in good yield under mild conditions using Cs2CO3. In the synthesis of geranyloxycoumarin derivatives, when 4-hydroxycoumarin reacts with geranyl bromide under mild conditions due to tautomeric keto-enol forms, 4-geranyoxycoumarin (3a), C-alkylated coumarin (3aa) and structure 3ab formed by hydrolysis and decarboxylation from 3aa were formed products. In addition, the alkylation reaction of 3-OH, 5-OH, 6-OH, 7-OH, and 8-OH coumarin except 4-OH group produced a high yield.
Probabilidad e incertidumbre en Keynes. Una revisión de tipo bayesiano
Authors: Jacobo Juan Esteban
Published: December 2021

Este articulo analiza el concepto de probabilidad en la obra de Keynes y propone un metodo para formalizar la nocion de la incertidumbre en la Teoría general utilizando el teorema de Bayes y el principio de maxima entropia. Una de las principales conclusiones es que, a pesar de compartir su rechazo del enfoque frecuentista de la estadistica, es poco razonable pensar que no se pueden determinar probabilidades numericas, aunque se cumpla algun criterio de objetividad.
Ciberplanificación, propiedad privada y cálculo económico
Authors: Espinosa Víctor I.
Published: December 2021

Este artículo revisa y discute las observaciones del profesor Maxi Nieto sobre algunos temas importantes de la moderna teoría del socialismo. En particular, su interpretación del argumento contra la “posibilidad” del cálculo económico sin derechos de propiedad privada desarrollado por la nueva generación de autores de la escuela austriaca. Centra la atención en cuestiones metodológicas para resaltar las deficiencias teóricas de algunas de las principales ideas defendidas por Nieto. También analiza su propuesta del ciber-comunismo como alternativa para superar el desafío del cálculo económico a través de las nuevas tecnologías de la información y la comunicación. Argumenta que su análisis es superficial y que el desafío de los austriacos sobre la imposibilidad del socialismo sigue siendo sólido.
Crisis de reproducción social y pandemia
Authors: Raffo Leonardo , Hernández Edwin Arbey
Published: December 2021

Este articulo analiza las dinamicas de acumulacion capitalista que han incidido en la extension de la pandemia de COVID-19 y en la magnitud de sus efectos sobre la economia y las sociedades. Argumenta que para entender la crisis economica y social causada por la pandemia es indispensable tener en cuenta la contradicción entre la acumulacion de capital y los procesos de reproduccion social, que se ha profundizado en los ultimos anos, junto con el resurgimiento de movimientos populistas y nacionalistas en diversos paises.
La práctica pedagógica del dibujo del natural en tiempos de pandemia
Authors: Patiño Núñez Alberto
Published: December 2021

El artículo propone una breve revisión de algunas ideas, planteamientos y estrategias que se emplean en la enseñanza de los cursos de Dibujo del Natural. Estos cursos prácticos artísticos de larga tradición en la Facultad de Arte y Diseño de la PUCP se han visto afectados debido a la compleja coyuntura producida por la pandemia de la COVID-19 del 2020 y la virtualización de muchos cursos de la Facultad. El propósito principal es situar y reflexionar acerca de la pertinencia de cursos de esta naturaleza que en apariencia parecieran no tener un espacio o relevancia en una educación virtual; también se consideran propuestas de enseñanza más contemporáneas de las artes visuales. El artículo da cuenta de los debates y dificultades a los que esta práctica se encuentra sometida e intenta dar luces sobre posibles escenarios futuros y su lugar en el contexto actual.
Diseño gráfico en el Perú de inicios del siglo XX: Los carteles avant garde de Elena Izcue, 1930-1940
Authors: Valenzuela Suárez Claudia Catherine
Published: December 2021

A Elena Izcue se le conoce por sus estudios artísticos y gráficos de la iconografía del arte precolombino. Sin embargo, es importante rescatar y visibilizar sus propuestas gráficas de carteles realizados entre 1930 y 1940, que se alejaron del arraigado concepto iconográfico peruano para adentrarse en una exploración formal y compositiva que tomó como referencia las manifestaciones artísticas y gráficas europeas. Esa experiencia le permitió hacer propuestas creativas e innovadoras que dialogaron con el lenguaje de las vanguardias y que luego entretejió con el lenguaje visual local. Fue un proceso interesante de transculturación visual en el que la vanguardia internacional influyó a Izcue a través del cartel y luego le dio el sentido identitario cuando regresó al Perú.
Imaginar es hacer una imagen
Authors: Orézzoli Pinillos Ana Lía
Published: December 2021

Este relato nace de la búsqueda del sueño y del descanso como un lugar de escape y fantasía. Las imágenes son una expresión del deseo de salir de la realidad y de la condición física, del puro cuerpo al que nos ha devuelto el virus. A partir del encierro, tuve la sensación de que mi cuerpo era algo que me dolía y que con facilidad podía hacerse pedazos. Empecé a hacer estas imágenes y a escribir mis sueños como un acto de resistencia a esa violencia que experimentaba. Recurro a la fotografía como un espacio posible para inventar un lugar con vestigios de aquello que no existe. Como menciona Bachelard (1965), “Si nos preguntaran cuál es el beneficio más precioso de la casa, diríamos: La casa alberga el ensueño, la casa protege al soñador, la casa nos permite soñar en paz” (p. 36).
Tradiciones discursivas en la historia del español americano. Difusión, contacto y desafíos
Authors: Garatea Grau Carlos
Published: December 2021

El concepto de tradiciones discursivas goza de extendido consenso en el ámbito de la historia de la lengua. En este trabajo se ofrecen algunas razones y ejemplos que justifican su utilidad en la historia del español americano y, en ella, de los efectos y expresiones del contacto con las lenguas indígenas de América. El propósito es simple: apreciar la relevancia de las tradiciones discursivas en la formación del español de América.
Kajian Hukum Islam Terhadap Praktik Simpan Pinjam di Kerukunan Kayubulan Kota Manado
Authors: Kasim Adriandi
Published: December 2021

Praktik simpan pinjam pada kerukunan Kayubulan menerapkan bunga sebesar sepuluh persen dan untuk anggota yang belum mampu mengembalikan pinjaman maka diwajibkan untuk membayar bunga pinjaman terlebih dahulu. Adapun rumusan masalah yang di angkat. Bagaimana praktik simpan pinjam pada kerukunan kayubulan di Kota Manado? Bagaimana tinjauan hukum Islam terhadap praktik simpan pinjam pada kerukuna Kayubulan Kota di Kota Manado? Penelitian ini bertujuan untuk mengetahui praktik simpan pinjam di kerukunan Kayubulan Wanea Kota Manado sudah berkesesuaian dengan Ijtima Ulama Komisi Fatwa Majelis Ulama (MUI) Indonesia tentang fatwa riba pada tanggal 22 syawal 1424 H/6 Desember 2003. Penelitian ini menggunakan Jenis penelitian lapangan (field research), dengan menggunakan metode pendekatan yuridis normatif. Hasil dari penelitian menunjukan bahwa praktik simpan pinjam kerukunan Kayubulan yang bertentangan dengan hukum Islam, karena sejak awal akad telah menentukan beberapa besar bunga pinjaman dan pihak kerukunan sudah memahami haramnya umat muslim mempraktikan riba, akan tetapi mereka masih menjalankan kerukunan tersebut. (The practice of savings and loans in the “Kerukunan Kayubulan” applies an interest of ten percent and for members who have not been able to repay the loan, they are required to pay the interest on the loan first. The formulation of the problem raised. How is the practice of saving and borrowing in the “Kerukunan Kayubulan” in Manado City? How is the review of Islamic law on the practice of savings and loans in the Kayubulan Kota harmony in Manado City? This study aims to determine the practice of savings and loans in the Kayubulan Wanea harmony, Manado City is in accordance with the Ijtima Ulama Fatwa Commission of the Indonesian Ulema Council (MUI) regarding the fatwa of usury on 22 Shawwal 1424 H/6 December 2003. This study uses a type of field research (field research). ), using a normative juridical approach. The results of the study show that the practice of saving and borrowing in “Kerukunan Kayubulan” is contrary to Islamic law, because from the beginning the contract has determined the majority of the loan interest and the harmony party has understood that it is forbidden for Muslims to practice usury, but they still carry out the harmony)
Perancangan Sistem Informasi Pendataan Alat Tulis Kantor Berbasis Web pada Fakultas Ekonomi dan Bisnis Islam UIN Raden Fatah Palembang
Authors: Mardiana Dwi
Published: December 2021

Penelitian ini bertujuan untuk menghasilkan sebuah rancangan interface untuk membangun sistem pendataan alat tulis kantor. Metode penelitian yang digunakan adalah deskriptif. Dalam penelitian ini sistem berjalan digambarkan dalam bentuk workflow diagram dan arus informasi sistem pendataan ATK yang telah dibuat digambarkan dalam bentuk data flow diagram (DFD). Penelitian ini menghasilkan rancangan interface sistem berdasarkan proses-proses yang telah diusulkan yang nantinya dapat diterapkan pada Fakultas Ekonomi dan Bisnis Islam.
Nilai-Nilai Pendidikan dalam Salat Jumat menurut Kajian Kitab Irsyadul ‘Ibad
Authors: Naini Oktamijul , Isnaini Muhammad , Halimatussakdiyah Halimatussakdiyah
Published: December 2021

Penelitian ini bertujuan untuk menganalisis nilai pendidikan dalam salat Jumat menurut kajian kitab Irsyadul ‘Ibad. Metode penelitian ini adalah kepustakaan. Data dianalisis dengan analisi isi. Penelitian ini menyimpulkan bahwa nilai-nilai pendidikan dalam salat Jumat menurut kitab Irsyadul ‘Ibad Karya Zainuddin Ibnu Abdul Aziz Al-Malybari yaitu nilai tawadu, disiplin, iffah dan sopan. Nilai tersebut menjadikan seseorang menuju muslim yang sejati karena mengajarkan tentang cara bertakwa dan beriman kepada Allah Swt serta berakhlak terpuji.
Applying Self-Directed Groupwork and Social Action Research Methodology with francophone parents of trans children and youth in Rural Quebec
Authors: Pullen Sansfaçon Annie , Pineault Dominique , Davis Jennifer , Dyer Jennifer , Julie James , Ens Manning Kimberley , Temple-Newhook Julia , Pickett Sarah
Published: December 2021

Parental support is an important protective factor in preventing suicide among trans youth. However, parents often struggle to accept their child’s gender transition.  Having access to a group and to meeting other parents facilitates the acceptance process, but support groups are rare and even more so outside urban areas. The research project discussed in this article was developed to understand specifically the experience of parents of francophone trans youth living in rural and remote communities in Quebec. A Self-Directed Group approach (Mullender, Ward and Fleming 2013), combined with Social Action Research (Author et al. 2015) was initiated to offer a platform for parents to explore the specificities of parenting a trans child in rural francophone Quebec.  Parents were recruited through social and traditional media and a series of group meetings was planned to collect data and as well as to facilitate the parents' mobilization.  Despite applying the Self-Directed Groupwork principles and process, many challenges were encountered, stimulating a number of reflections on the use of self-directed group work and social action in remote geographical areas. This paper explores some of those challenges and discusses a possible way forward for research.
Ressurgência das imagens
Authors: Simão Luciano Vinhosa
Published: December 2021

No presente artigo, apresento as linhas gerais de uma pesquisa inicial cujo interesse está orientado para as teorias, levando em consideração às modulações de uso que as diferentes culturas dão à imagem em face da ressurgência desta na arte metropolitana, campo tradicional das representações eurocêntricas, hoje em disputa com as culturas periféricas, em especial, o caso brasileiro. Diante da transculturalização que esse processo promove, e para fins conceituais e metodológicos, iremos considerar três modalidades de agências cruzadas que nos servirão de recorte aos estudos que pretendemos realizar em relação às imagens da arte: 1) agência transcendente; 2) agência afeccional; 3) agência metamórfica.
Effects of dry particle coating with nano- and microparticles on early compressive strength of portland cement pastes
Authors: Yorulmaz Hediye , Özuzun Sümeyye , Uzal Burak , İlkentapar Serhan , Durak Uğur , Karahan Okan , Atiş Cengiz Duran
Published: December 2021

It is known that nano-and microparticles have been very popular in recent years since their advantages. However, due to the very small size of such materials, they have very high tendency to agglomeration particularly for nanoparticles. Therefore, it is critical that they are properly distributed in the system to which they are added. This paper investigated the effects of dry particle coating with nano-and microparticles to solve the agglomeration problem. For a clear evaluation, paste samples were preferred to detemine the compressive strength. Nano-SiO2 and nano-CaCO3, micro-CaCO3 and micro-SiO2, also known as silica fume, were selected as particulate additives. It was studied by the addition of various percentages (0.3, 0.7, 1, 2, 3 and 5%) of nano-and microparticles in cementitious systems, replacing cement by weight with and without dry particle coating. Dry particle coating was made by using a high-speed paddle mixer. Portland cement and additive particles were mixed at 1500 rpm for 30 seconds in high-speed powder mixer designed for this purpose. The 3-day compressive strength of the cement-based samples to which particles were added at the specified rates was determined and the effect of the dry particle coating on the early strength was investigated. According to the results, it was observed that the production of paste with the dry particle coating technique gave higher compressive strength compared to the production of paste directly in early period. Especially with dry particle coating, compressive strength increased more than 100% in paste samples containing 0.3% nano-SiO2 compared to direct addition without coating.
Decision-making model based multilayer perceptrons for estimation of optimum design properties for truss structure
Authors: Yücel Melda , Bekdaş Gebrail , Nigdeli Sinan Melih
Published: December 2021

Many branches of the structural engineering discipline have many problems, which require the generating an optimum model for beam-column junction area reinforcement, weight lightening for members such a beam, column, slab, footing formed as reinforced concrete, steel, composite, and so on, cost arrangement for any construction, etc. With this direction, in the current study, a structural model as a 5-bar truss is handled to provide an optimum design by determining the fittest areas of bar sections. It is aimed that the total bar length is minimized through population-based metaheuristic algorithm as teaching-learning-based optimization (TLBO). Following, the decision-making model is developed via multilayer perceptrons (MLPs) by performing an estimation application to enable directly foreseen of the optimal section areas and total length of bars, besides, the approximation and correlation success are evaluated via some metrics. Thus, determination of the real optimal results of unknown and not-tested designs can be realized with this model in a short and effective time.
Escuela rural: análisis bibliométrico internacional (2015-2019)
Authors: Alvarez-Alvarez Carmen , Garcia-Prieto Francisco Javier
Published: December 2021

En todos los países hay escuelas rurales, con peculiaridades que las hacen únicas, a la par que comparten aspectos sustantivos. Presentamos un estudio bibliométrico en el que se analizan 32 estudios sobre escuela rural en el periodo 2015-2019 tomados de la Web of Science y Scopus. Se han filtrado en base a unos parámetros y se han analizado conforme a estos indicadores: impacto, temática, territorio, objetivo, tipo de estudio, técnicas de investigación, sujetos, tipo de escuela, resultados, conclusiones y limitaciones. Los resultados muestran que predominan los estudios locales, cualitativos, centrados en asuntos curriculares y desarrollados con maestros. Es necesario contar con estudios publicados en primeros cuartiles, emplear más de una técnica de recogida de información, mencionar las características de las escuelas rurales, apostar por muestras amplias y evitar estudios accesorios.
PREDIKSI BERAT TUBUH SAPI PERAH FRIESIAN-HOLSTEIN MENGGUNAKAN MODEL VON BERTALANFFY
Authors: Larasati Niken , Sulistyoningrum Tri Puji , Estri Mutia Nur , Sihwaningrum Idha , Reorita Rina
Published: December 2021

Pada makalah ini dibahas mengenai prediksi berat tubuh sapi perah Friesian-Holstein menggunakan model Von Bertalanffy. Laju metabolisme pada model terdiri dari anabolisme dan katabolisme. Prediksi berat tubuh sapi perah ini penting karena dapat digunakan untuk menentukan usia kawin  pertama kali sapi perah FH. Usia kawin pertama yang tidak tepat dapat menyebabkan produksi susu yang rendah dan tidak tercapainya berat tubuh pedet yang ideal. Dari hasil simulasi diperoleh konstanta anabolisme sebesar 0,3854 dan konstanta katabolisme sebesar 0,0438. Dengan konstanta tersebut, diperoleh rata-rata kesalahan absolut sebesar 4,9708% (6,5358 kg). Selanjutnya, diperoleh hasil bahwa sapi dapat dikawinkan pada saat memiliki berat tubuh 273,9152 kg sampai 303,2340 kg dengan umur 59-66 minggu (14-16 bulan).
2D Image-based calibration of rolling resistance in 3D discrete element models of sand
Authors:   Polytechnic University of Catalonia, Arroyo Marcos , Rorato Riccardo ,   Polytechnic University of Catalonia, Previtali Marco ,   University of Dundee, Ciantia Matteo ,   University of Dundee
Published: December 2021

Contact rolling resistance is the most widely used method to incorporate particle shape effects in the discrete element method (DEM). The main reason for this is that such approach allows for using spherical particles hence offering substantial computational benefits compared to non-spherical DEM models. This paper shows how rolling resistance parameters for 3D DEM models can be easily calibrated with 2D sand grain images.
Grain roughness effect on the critical state line of crushable sands
Authors:   Polytechnic University of Catalonia, Lei Jiangtao , Arroyo Marcos ,   Polytechnic University of Catalonia, Ciantia Matteo ,   University of Dundee, Zhang Ningning ,   RWTH Aachen University
Published: December 2021

A recently proposed DEM model for materials with rough crushable grains (Zhang et al. 2021; Ciantia et al. 2015; Otsubo et al. 2017) is here employed to examine the effect of contact roughness on the critical state line, a property of granular materials which is a) fundamental for the evaluation of liquefaction risk and liquefied responses and b) easily accessible through DEM simulation (Ciantia et al. 2019).
Spatio-temporal analysis of remotely sensed rainfall datasets retrieved for the transboundary basin of the Madeira River in Amazonia
Authors:   Civil Engineering Program, Alberto Luiz Coimbra Institute for Postgraduate Studies and Research in Engineering (COPPE), Federal University of Rio de Janeiro (UFRJ), de Souza Vinicius Alexandre Sikora , Moreira Daniel Medeiros ,   Department of Hydrology, Companhia de Pesquisa de Recursos Minerais (CPRM), Geological Survey of Brazil, Rotunno Filho Otto Corrêa ,   Civil Engineering Program, Alberto Luiz Coimbra Institute for Postgraduate Studies and Research in Engineering (COPPE), Federal University of Rio de Janeiro (UFRJ), Rudke Anderson Paulo ,   Federal University of Minas Gerais, Andrade Claudia Daza ,   Federal Rural University of Rio de Janeiro, De Araujo Lígia Maria Nascimento ,   Brazilian National Water Agency
Published: December 2021

Rainfall is recognized as the most important driving force of the hydrologic cycle. To accurately represent the spatio-temporal rainfall variability continues to be an enormous hydrological task when using commonly sparse, if available, rain gauges networks. Therefore, the present study devoted a special effort to analyze the robustness of some satellite rainfall products, notably the datasets hereafter named as (i) CHIRP (Climate Hazards Group InfraRed Precipitation), (ii) CHIRPS (Climate Hazards Group InfraRed Precipitation with Station data), (iii) 3B42, and (iv) 3B42RT of the Tropical Rainfall Measuring Mission (TRMM), to adequately represent the pluviometric regime in the Madeira river basin. To assess the accuracy of acquired remotely sensed rainfall products, comparisons to observational available rain gauges usually taken as ground-truth in the literature, despite their well-known limitations, were performed. Wavelet analysis was also used to validate the performance of the referred satellite products by means of extracting the corresponding cycles, frequencies, and tendencies along the available time series across the studied basin. The results showed that the data sources CHIRPS and CHIRP better represent the pluviometric phenomenon by means of their monthly accumulated rainfall in the Madeira river basin when compared to the 3B42 and 3B42RT products taking into account rain gauges as baseline information. The CHIRPS product performed the best among the selected rainfall estimators for the Madeira river basin. Further analysis brought up also another very interesting result related to non-rainfall periods, which is usually not reported. However, such evaluation is quite important in hydrology when examining run sequences of droughts and consequent effects in the water balance at the watershed scale. Highly accurate estimates in the sense of identifying non-rainfall periods by remotely sensed information was achieved, which represents an additional and valuable asset of satellite rainfall products. It is worthwhile to say that this perspective deserves to receive much more attention in the literature in order to deeply discuss the water-energy-food nexus.
Amplitude equation formalism for reaction—subdiffusion systems
Authors: Zenyuk Dmitry Alexeevich , Malinetskii Georgii Gennadyevich
Published: December 2021

The paper presents derivation of the amplitude equation for the Hopf bifurcation in the two-component system with nonlinear chemical kinetics and subdiffusion. Anomalous diffusion transport is described via Caputo fractional derivatives. The obtained amplitude equation is much more complex compared to the case of normal diffusion because solutions of fractional order linear differential equations have inconvenient behavior.
Factors Affecting Quality of Life of Hemodialysis Patients - with Focus on Resilience, Symptom Experience and Self-management
Authors: Jung Hyun-Young , Park Yong-Kyung , Suh Soon-Rim
Published: December 2021

Objectives: The purpose of this study was to investigate the factors affecting quality of life of hemodialysis patients.Methods: As a descriptive study, the data were collected from 172 hemodialysis patients receiving hemodialysis at 4 medical institutions. Collected data were analyzed using descriptive statistics, t-test, ANOVA, Pearson correlation analysis and multiple regression.Results: The influential variable of the quality of Life of hemodialysis patients were resilience, symptom experience and monthly income less than 2 million won. These factors explained for 48.7% of the quality of Life of hemodialysis patients.Conclusions: The most ideal method to increase the quality of hemodialysis patients’ lives is to develop an integrated nursing intervention that will increase patients’ resilience and reduce the intensity of symptoms.
Challenges and Development Strategy of Sharia Insurance in an Era of Economic Disruption
Authors: Syahputra Angga , Nurtiyasari Devi
Published: December 2021

The presence of Islamic insurance is an alternative to avoid conventional insurance, which is considered to have elements of usury, maytsir, gharar and zholim. In the era of economic disruption, Islamic insurance players and customers are waiting for the government's strategic policies as regulators and facilitators. The formulation of a sharia insurance development strategy policy begins with analyzing the obstacles to developing sharia insurance in Indonesia. These constraints mean that the number of sharia insurance customers in Indonesia is not maximal. These obstacles include the lack of socialization and promotion, inadequate use of technology, lack of product and service development, lack of knowledge, and the existence of conventional insurance. Based on these constraints, strategies for developing sharia insurance in Indonesia that can be carried out include maximizing socialization and promotion, maximizing the use of technology, developing products and services, increasing literacy, and market penetration. This research aims to analyze Islamic insurance's constraints and development strategies using a mathematical method, namely the Analytic Network Process (ANP) method so that scientific studies support policy recommendations. Furthermore, in this study, the ANP method was adopted in a survey design involving several respondents. The heterogeneity of the assessments of some respondents is expected to provide a more rational alternative. The analysis results using the ANP method are priority constraints to get more attention and priority strategies that can be used to formulate policies to make them more focused.
120 YEARS OF GENETICS - FROM THE HISTORY OF SCIENCE AND ITS ROLE IN EDUCATION
Authors:   Amur State Medical Academy of the Ministry of Health of the Russian Federation, Blagoveshchensk, Gordienko E.N.
Published: December 2021

Significance. The recent anniversary - the 120th anniversary of genetics - symbolizes importance of science in all spheres of both natural science and humanitarian knowledge. Many health problems in Russia and abroad, including infections (SARS-CoV-2 virus), hereditary, multifactorial diseases, congenital malformations, ecological factors have genetic background. Knowledge of the basics of genetics helps to understand the role of genetic information in the implementation of phenotypic features of the human body with the participation of environmental factors to assess their positive or negative role in health formation and development. Purpose. a) To attract attention of all participants of the educational process to aspects of genetics in connection with problems of demographic situation and health in Russia to learn the basics of health; b) To evaluate temporal regulations related to teaching genetics in the system of the existing educational standards (FSES) in both secondary schools, colleges and high schools as insufficient and not meeting needs of the society and learners in understanding the personalized medicine and health basics; c) To substantiate necessity of studying genetics in connection with the human body and biota in the 21st century. Material for this article served scientific databases: eLibrary, PubMed, Web of Science, and Scopus. Results. The rationale of studying genetics by all participants of the Russian education at all levels was substantiated. An excursus into history of genetics was carried out to review its formation stages and recognize achievements of the domestic scientists - their contribution into creation of the science bases and its great discoveries. The need for genetic information for developing knowledge about origins of health and causes of its possible problems was pointed out and the role of methods of gene diagnostics, gene correction in preventing hereditary diseases and congenital defects was emphasized. Conclusion. The genetic component in the system of the Russian education should become universal in the cognitive model of "Nature-Man-Society". This knowledge provides basis for understanding and managing health. Genetics explores mysteries of the past, diagnoses problems of the present (health - disease) and predicts the future. For many the engine in mastering the basics of genetics will be a future profession (medicine, pedagogy, psychology, sociology, ecology, veterinary medicine, botany), but absolutely for everyone will be relevant to the study of their "self" for self-discovery of their roots, their future and conditions of their lives.
Temas de investigación relevantes en ciencias administrativas: una mirada desde el análisis de redes
Authors: Del Río-Cortina Abel Aníbal , Amador-Moncada Jorge Armando , Rentería-Ramos Rafael Ricardo , Urrea-Ospina Iván Darío
Published: December 2021

Existen fuertes críticas a la baja relación que existe entre los procesos de investigación y el contexto empresarial en las facultades, los programas de administración y las escuelas de negocios poco posicionados. Este documento tiene como objetivo  determinar  los  temas  relevantes  en ciencias administrativas mediante la aplicación de análisis de redes para identificar las instituciones que manejan temas recurrentes, aquellas que abordan temas especializados y los territorios con  investigación en el campo administrativo.  Se  identificaron las mejores facultades, programas de administración  y escuelas  de  negocios  a  nivel  mundial  y  nacional  y  a  partir  de  esta  selección,  se  construyó  un  modelo  relacional  de  las interacciones entre las instituciones y las temáticas utilizando la teoría de redes. Se implementó este tipo de análisis dadoque  permite  la  revisión  sistemática  y  sus  resultados  se  convierten  en  insumos  que  contribuyen  a  la  posterior  toma  de decisiones  por  parte  de  las  instituciones  inmersas  en  este  campo.  Entre  los  resultados  se  encuentran  como  nodos institucionales notables la Escuela de Negocios de Columbia, la Escuela de Negocios Insead, la Universidad de Negocios Cornell,  la  Escuela  de  Negocios  de  Harvard  y,  finalmente,  la  Escuela  de  Gestión  SLOAN  del  Massachusetts  Institute  of Technology.   Finalmente,   se   identificaron   como   nodos   temáticos   relevantes   aquellos   relacionados   con   finanzas, emprendimiento, globalización y liderazgo.
Laboratory Investigation of Impact of Slickwater Composition on Multiphase Permeability Evolution in Tight Sandstones
Authors: Abaa Kelvin , Wang John , Elsworth Derek , Ityokumbul Mku
Published: December 2021

Fracturing fluid filtrate that leaks off during injection is imbibed by strong capillary forces present in low-permeability sandstones and may severely reduce the effective gas permeability during cleanup and post-fracture production. This work aims to investigate the role fracturing fluid filtrate from slickwater has on rock-fluid and fluid-fluid interactions and to quantify the resulting multiphase permeability evolution during imbibition and drainage of the filtrate by means of specialized core laboratory techniques. Three suites of experiments were conducted. In the first suite of experiments, a fluid leakoff test was conducted on selected core samples to determine the extent of polymer invasion and leakoff characteristics. In the second suite, multigas relative permeability measurements were conducted on sandstone plugs saturated with fracturing fluid filtrate. A combination of controlled fluid evaporation and pulse decay permeability technique was used to measure liquid and gas effective permeabilities for both drainage and imbibition cycles. These experiments aim to capture dynamic permeability evolution during invasion and cleanup of fracturing fluid (slickwater). The final suite of experiments consists of adsorption flow tests to investigate, identify, and quantify possible mechanisms for adsorption of the polymeric molecules of friction reducers present in the fluid filtrate to the pore walls of the rock sample. Imbibition tests and observations of contact angles were conducted to validate possible wettability changes.

Results from multiphase permeability flow tests show an irreversible reduction in endpoint brine permeability and relative permeability with increasing concentration of friction reducer. Our results also show that effective gas permeability during drainage/cleanup of the imbibed slickwater fluid is controlled to a large degree by trapped gas saturation than by changes in interfacial tension. Adsorption flow tests identified adsorption of polymeric molecules of the friction reducer present in the fluid to the pore walls of the rock. The adsorption friction reducer increases the wettability of the rock surface and results in the reduction of liquid relative permeability. The originality of this work is to diagnose formation damage mechanisms from laboratory experiments that adequately capture multiphase permeability evolution specific to a slickwater fluid system, during imbibition and cleanup. This will be useful in optimizing fracturing fluid selection.
The Nuclear Factor-Kappa B Signaling Pathway is Involved in Transient Receptor Potential Vanilloid 4-Mediated Inflammatory Responses and Neuronal Death in Mice with Pilocarpine-Induced Status Epilepticus
Authors: An Dong , Qi Xiuting , Li Kunpeng , Xu Weixing , Wang Yue , Chen Xi , Sha Sha , Wu Chunfeng , Du Yimei , Chen L
Published: December 2021

The blockage of transient receptor potential vanilloid 4 (TRPV4) greatly reduces hippocampal neuronal injury in mice with temporal lobe epilepsy through inhibiting inflammation. NF-κB signaling pathway is activated during epilepsy, leading to enhanced inflammation and neuronal injury. Here, we explored whether TRPV4 blockage could affect the NF-κB pathway in mice with pilocarpine-induced status epilepticus (PISE). Application of a TRPV4 antagonist markedly attenuated the PISE-induced increase in hippocampal HMGB1, TLR4, phospho (p)-IκK (p-IκK), and p-IκBα protein levels, as well as those of cytoplasmic p-NF-κB p65 (p-p65) and nuclear NF-κB p65 and p50; in contrast, the application of GSK1016790A, a TRPV4 agonist, showed similar changes to PISE mice. Administration of the TLR4 antagonist TAK-242 or the NF-κB pathway inhibitor BAY 11-7082 led to a noticeable reduction in the hippocampal protein levels of cleaved IL-1β, IL-6 and TNF, as well as those of cytoplasmic p-p65 and nuclear p65 and p50 in GSK1016790A-injected mice. Finally, administration of either TAK-242 or BAY 11-7082 greatly increased neuronal survival in hippocampal CA1 and CA2/3 regions in GSK1016790A-injected mice. We conclude that TRPV4 activation increases HMGB1 and TLR4 expression, leading to IκK and IκBα phosphorylation and, consequently, NF-κB activation and nuclear translocation. The resulting increase in pro-inflammatory cytokine production is responsible for TRPV4 activation-induced neuronal injury. Meanwhile, blocking TRPV4 can downregulate HMGB1/TLR4/IκK/κBα/NF-κB signaling following PISE onset, an effect that may underlie the neuroprotective ability of TRPV4 blockage in mice with PISE.
S-Ketamine As An Adjuvant in Patient-controlled Intravenous Analgesia for Prevention of Postpartum Depression: A Randomized Controlled Trial
Authors: Han Yaqian , Li Pule , Miao Mengrong , Tao Yuan , Xia Kang , Zhang Jiaqiang
Published: December 2021

(1) Background: Postpartum depression (PPD) is a common complication after cesarean section. Recent studies have shown that intravenous S-ketamine during surgery could be effective in preventing PPD. However, no evidence shows S-ketamine used in patient-controlled intravenous analgesia (PCIA) could reduce the incidence of PPD. Our aim was to explore the effect of S-ketamine as an adjuvant in patient-controlled intravenous analgesia (PCIA) for prevention of postpartum depression. (2) Methods: In a single center, 375 parturients scheduled to undergo cesarean section were recruited and randomly assigned to two groups: Control group (C group) or S-ketamine group (S group). Parturients in both groups received PCIA, the formula of Group C: sufentanil 2 μg/kg + tropisetron 10 mg, S group was the same as C group except 0.5mg/kg S-ketamine. The primary outcome was the incidence of PPD measured by the Edinburgh Postnatal Depression Scale (EPDS) after surgery. The secondary outcomes were EPDS scores, Visual analogue scale (VAS) scores, and Ramsay Sedation Scale (RSS) scores, and incidence of related adverse events. (3) Results: A total of 275 puerpera were finally included and randomly assigned to two groups. The incidence of depression at postoperative 3, 14, 28days in C group and S group were 17.6%vs8.2%, P<0.05;24.2%vs9.8%, P<0.05, and 19.0%vs 17.2%, P=0.76, respectively). As for EPDS scores, C group and S group at 3,14, and 28 days after cesarean were 7.65±3.14vs6.00±2.47, p<0.05,7.62±3.14vs6.38±2.67, p<0.05, and 7.35±3.17vs6.90±2.78, p=0.15, respectively. Adverse events such as headache and nausea were 3.3% vs 4.1%, p=0.755; 5.9%vs8.2%, p=0.481. (4) Conclusions: 0.01mg/kg/h S-ketamine as an adjuvant in patient-controlled intravenous analgesia can significantly reduce the incidence of postpartum depression within 14 days and relieve postoperative pain within 48h after cesarean section, without increasing the incidence of adverse reactions.Trial registration: ChiCTR, ChiCTR2100050263，retrospectively registered. Registered 24/08/2021.