bluuebunny/crossref_metadata_2025 huggingface dataset:
PREVALENCE AND CORRELATION OF METABOLIC SYNDROME IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD)
Authors:   Junior Resident, Department of General Medicine, Dr BalasahebVikhe Patil Rural Medical College, Loni., Sunil Bhelekar Runjan , Mahajan S.N. ,   Professor, Department of General Medicine, Dr BalasahebVikhe Patil Rural Medical College, Loni.
Published: May 2024

Background: Chronic obstructive pulmonary disease (COPD) and metabolic syndrome (MetS) are prevalent chronic conditions with significant impacts on public health. Despite evidence suggesting a bidirectional relationship between COPD and MetS, data on the prevalence and correlation of MetS in COPD patients remain limited.This cross-sectional study aimed to investigate the prevalence of MetS in COPD patients admitted at Rural Medical College Loni and explore its correlation. Methods: A total of 50 COPD patients aged 40 years and above were recruited. Demographic and clinical data were collected through face-to-face interviews and medical record review. Diagnosis ofMetS was done based on the International Diabetes Federation criteria. Logistic regression analysis was performed to identify factors associated with MetS in COPD patients. Results: The mean age of the study population was 60.92 Â± 8.97 years, with 76% being male. The prevalence of MetS among COPD patients was42%. The majority of patients with MetS exhibited grade 3 dyspnea based on modified medical research council grading (MMRC). MetS was most prevalent among patients with GOLD stage III disease. Conclusion: Metabolic syndrome is highly prevalent among COPD patientsadmitted at Rural Medical College Loni andpatients with MetS present with more severe disease and frequent exacerbations. Identification of MetS in COPD patients is crucial for comprehensive disease management and warrants integrated care approaches targeting both respiratory and metabolic health. Further research is needed to elucidate the underlying mechanisms linking COPD and MetS and develop tailored interventions to improve outcomes in this population.
MALTRAITANCE INFANTILE : ENTRE CULTURE ET EDUCATION
Authors:   Laboratoire de Recherche Enfance, Sante et Developpement , Universite Caddi Ayad, Marrakech, Maroc., Akenssous M. , Taoubane F. ,   Laboratoire de Recherche Enfance, Sante et Developpement , Universite Caddi Ayad, Marrakech, Maroc., Mouachi S. ,   Laboratoire de Recherche Enfance, Sante et Developpement , Universite Caddi Ayad, Marrakech, Maroc., Aabbassi B. ,   Laboratoire de Recherche Enfance, Sante et Developpement , Universite Caddi Ayad, Marrakech, Maroc., Adali I. ,   Service Universitaire de Psychiatrie, CHU Mohamed Vi, Marrakech, Maroc., Manoudi F. ,   Service Universitaire de Psychiatrie, CHU Mohamed Vi, Marrakech, Maroc.
Published: May 2024

La maltraitance infantile, un fleau mondial, varie selon les normes culturelles. Ce qui est abusif dans une culture peut etre accepte dans une autre, et les stereotypes de genre influencent la perception de la maltraitance. Le deni est courant, rendant essentielle leducation sur les signes de maltraitance pour une detection precoce. Les cas cliniques de Bilal et Sara illustrent limportance dune intervention culturelle adaptee. Pour prevenir efficacement, il faut respecter les pratiques educatives traditionnelles tout en promouvant des approches non violentes. Une approche holistique et culturelle est cruciale pour assurer le bien-etre des enfants.
MATERNAL- AND FETAL-RISK FACTORS ASSOCIATED WITH LATEPRETERM AND EARLY TERM NEONATECOMPARED TO FULL TERM NEONATE BIRTH IN GARISSA COUNTY
Authors:   Department of Public Health, Masinde Muliro University of Science and Technology P. O. Box P.O BOX 190- 50100, Kakamega Kenya., Amolo (MSc) Tom , Raballah (PhD) Evans ,   Department of Medical Laboratory Science, Masinde Muliro University of Science and Technology P. O. Box P.O BOX 190- 50100, Kakamega Kenya., Olayo (PhD) Rose ,   Department of Public Health, Masinde Muliro University of Science and Technology, P. O. Box 190- 50100, Kakamega Kenya., C. Esendi (MSc) Gladys ,   Department of Medical Laboratory Science, Masinde Muliro University of Science and Technology, P. O. Box 190- 50100, Kakamega Kenya., Otieno (PhD) Walter ,   Department of Paediatrics and Child Health, School of Medicine, Maseno University, Private Bag, Maseno Kenya.
Published: May 2024

Despite late preterm neonates (LPN) and early term neonates (ETN) constitutingmajority of preterm births globally, the risk factors associated with these preterm births, in Garissa County are largely unexplored. This study aimed to identify maternal and fetal risk factors associated with LPN and ETN births relative to their full-term counterpartsin Garissa County. The study was conducted at Garissa County Referral Hospital. A prospective cohort studythat employed convenience sampling to enroll mother-neonate pairs. Data were collected using pretested and validated questionnaires and analyzed using STATA version 17. Multinomial logistic regression analysis was performed to determine Relative Risk Ratio. The P-value was generated at Î±=0.05 and P<0.05 was considered statistically significant. related risk factors associated with birth of LPN, ETN and FTN were maternal age (P=0.042), occupation (P=0.024), ethnicity (P=0.021), religion (P=0.016) and absence of previous abortion/still birth/premature deliveries (P=0.015). Birth weight was associated with LPN (P<0.001), while FTN had higher likelihood of delayed initiation of breastfeeding (P=0.038) but were less likely to have feeding difficulties compared to LPN and ETN (P=0.012). A comparison of fit model with the complete set of predictors with an intercept-only, or null modelrevealed that P-values for maternal (P=0.0175) and fetal (P<0.001) related risk factors were less than Fisherâ€™s value of 0.05, hence the null hypothesis was rejected. - and fetal-related risk factors associated with LPNs and ETNsare distinct from those of FTNs.
VITESSE DE RECOMBINAISON DYNAMIQUE A LA JONCTION ET EN FACE ARRIERE : APPLICATION A LA DETERMINATION DE LEPAISSEUR OPTIMUM DE LA BASE (P) DUNE PHOTOPILE (N+/P/P+) AU SILICIUM CRISTALLIN SOUS ECLAIREMENT POLYCHROMATIQUE EN MODULATION DE FREQUENCE
Authors:   Groupe International de Recherche en Energie Renouvelable (GIRER). BP. 15003, Dakar, Senegal., Niane Matar , Abderrahim Ould El Moujtaba Mohamed ,   Groupe International de Recherche en Energie Renouvelable (GIRER). BP. 15003, Dakar, Senegal.,   Faculte des Sciences et Techniques, Universite de Nouakchott, -Mauritanie., Loum Khady ,   Groupe International de Recherche en Energie Renouvelable (GIRER). BP. 15003, Dakar, Senegal.,   Universite Iba Der THIAM de Thies, Senegal., Simpore Rasmane ,   Groupe International de Recherche en Energie Renouvelable (GIRER). BP. 15003, Dakar, Senegal.,   Universite Nobert ZONGO, Koudougou, Burkina Faso., Diatta Ibrahima ,   Groupe International de Recherche en Energie Renouvelable (GIRER). BP. 15003, Dakar, Senegal., Traore Youssou ,   Groupe International de Recherche en Energie Renouvelable (GIRER). BP. 15003, Dakar, Senegal.,   Universite Iba Der THIAM de Thies, Senegal., Thiame Moustapha ,   Groupe International de Recherche en Energie Renouvelable (GIRER). BP. 15003, Dakar, Senegal.,   Universite Assane SECK, Ziguinchor, Senegal., Gueye Sega ,   Groupe International de Recherche en Energie Renouvelable (GIRER). BP. 15003, Dakar, Senegal.,   Faculte des Sciences et Technologies de leducation et de la Formation-Departement de Physique et Chimie, Universite Cheikh Anta DIOP, Dakar-Senegal., Sissoko Gregoire ,   Groupe International de Recherche en Energie Renouvelable (GIRER). BP. 15003, Dakar, Senegal.
Published: May 2024

Par resolution de lequation de diffusion en regime dynamique relative a la densite de porteurs minoritaires de charge dans la base(p), de la photopile sous eclairement polychromatique, munie des conditions aux limites associees aux vitesses de recombinaison a la jonction et en face arriere, lexpression de la densite du photocourant dynamique est etablie. Elle permet de deduire les expressions de la vitesse de recombinaison dynamiquedes porteurs minoritaires de charge a la jonction et en face arriere de la base, qui par comparaison graphique, conduisent a la determination de lepaisseur optimum de la base de la photopile, pour chaque valeur de la frequence de modulation de la lumiere incidente.
ETUDE DUNE PHOTOPILE (N+/P/P+) AU SILICIUM CRISTALLIN SOUS ECLAIREMENT POLYCHROMATIQUE ENMODULATION DE FREQUENCE : EFFET DE LA VITESSE SURFACIQUE DE RECOMBINAISON, DE LA FREQUENCE ET DE LEPAISSEUR SUR LES PARAMETRES ELECTRIQUES
Authors:   Groupe International de Recherche en Energie Renouvelable (GIRER). BP. 15003, Dakar, Senegal., Niane Matar , Abderrahim Ould El Moujtaba Mohamed ,   Groupe International de Recherche en Energie Renouvelable (GIRER). BP. 15003, Dakar, Senegal.,   Faculte des Sciences et Techniques, Universite de Nouakchott, -Mauritanie., Loum Khady ,   Groupe International de Recherche en Energie Renouvelable (GIRER). BP. 15003, Dakar, Senegal.,   Universite Iba Der THIAM de Thies, Senegal., Simpore Rasmane ,   Groupe International de Recherche en Energie Renouvelable (GIRER). BP. 15003, Dakar, Senegal.,   Universite Nobert ZONGO, Koudougou, Burkina Faso., Diatta Ibrahima ,   Groupe International de Recherche en Energie Renouvelable (GIRER). BP. 15003, Dakar, Senegal., Traore Youssou ,   Groupe International de Recherche en Energie Renouvelable (GIRER). BP. 15003, Dakar, Senegal.,   Universite Iba Der THIAM de Thies, Senegal., Thiame Moustapha ,   Groupe International de Recherche en Energie Renouvelable (GIRER). BP. 15003, Dakar, Senegal.,   Universite Assane SECK, Ziguinchor, Senegal., Gueye Sega ,   Groupe International de Recherche en Energie Renouvelable (GIRER). BP. 15003, Dakar, Senegal.,   Faculte des Sciences et Technologies de leducation et de la Formation-Departement de Physique et Chimie, Universite Cheikh Anta DIOP, Dakar-Senegal., Sissoko Gregoire ,   Groupe International de Recherche en Energie Renouvelable (GIRER). BP. 15003, Dakar, Senegal.
Published: May 2024

Letude de la photopile monofaciale (n+/p/p+) au silicium cristallin a travers la resolution de lequation de diffusion en regime dynamique relative a la densite de porteurs minoritaires de charge dans la base(p), munie des conditions aux limites associees aux vitesses de recombinaison a la jonction et en face arriere, conduit aux caracteristiques electriques, courant-tension, puissance-tension delivree et le facteur de forme. Ce travail montre et analyse sur ces quantites,les effetsde la frequence de modulation de la lumiere polychromatique incidente, de la vitesse de recombinaison des porteurs minoritaires de charge en face arriere et de lepaisseur de la base de la photopile.
SAFETY AND FEASIBILITY OF THE THREE PORT TECHNIQUE FOR CONCOMITANT CHOLECYSTECTOMY DURING SLEEVE GASTRECTOMY: A COMPREHENSIVE ANALYSIS AND CLINICAL IMPLICATIONS
Authors:   Department of Surgery, College of Medicine, Taif University, Taif, Saudi Arabia., M. Almalki Owaid ,   Department of Surgery, Alhada Military Hospital, Taif, Saudi Arabia.
Published: May 2024

Introduction:Obesity, a prevalent global health issue, has led to an increased demand for bariatric surgeries, with laparoscopic sleeve gastrectomy (LSG) being a preferred option due to its efficacy and minimal invasiveness. Concomitant cholecystectomy (CC) during LSG has gained traction among patients with obesity and gallstones. While various techniques have been explored, concerns persist regarding safety and efficacy. Our study aims to evaluate the feasibility and outcomes of a three-port laparoscopic technique for this combined procedure. Methodology:Ahigh-volume bariatric center in Saudi Arabia conducted a retrospective cohort study involving patients who underwent three-port sleeve gastrectomy (3PSG) with CC between January 2022 and January 2024. We collected and analyzed data on demographics, preoperative evaluation, intraoperative details, and postoperative outcomes using descriptive statistics. Results:Out of 360 LSG patients, 76 underwent CC with the three-port technique. The mean age was 42.18 years, with a female predominance (71.0%) and a mean BMI of 44.67 kg/m2. Intraoperatively, the mean operative time was 109.8 minutes, with minimal blood loss and no complications or conversions to open surgery. The average hospital stay was 2.1 days. Postoperatively, the complication rate was 4%, primarily consisting of early bleeding, port-site infection, and atelectasis, all of which were managed conservatively. No severe complications, mortalities, or thrombotic events occurred during the 3-month follow-up. Conclusion:Thethree-port laparoscopic technique for concomitant cholecystectomy during sleeve gastrectomy appears safe and feasible, offering favorable outcomes in terms of operative time, blood loss, and postoperative complications. This approach presents a promising option for minimizing surgical trauma and enhancing recovery in obese patients who require both procedures.
EXPLORING THE RELEVANCE OF SRI AUROBINDOS INTEGRAL EDUCATION PHILOSOPHY IN CONTEMPORARY EDUCATIONAL PRACTICES
Authors:   Dept. of Education, State Aided College Teacher, Raja Narendra Lal Khan Womens College (Autonomous)., Sing Puspa
Published: May 2024

In todays educational landscape, educators grapple with the challenge of nurturing students for holistic development and lifelong learning amidst a rapidly evolving world. The Integral Education Philosophy of Sri Aurobindo provides significant insights in line with contemporary teaching methods. Sri Aurobindos philosophy, which emphasises the harmonious development of physical, mental, emotional, and spiritual elements, promotes education to help people realise their full potential in order to promote planetary change, social harmony, and personal fulfilment. The current movement towards student-centred learning approaches is in line with core ideas including experiential learning, holistic growth, individualised teaching, multidisciplinary integration, ethical cultivation, and spiritual improvement. This qualitative study examines how Integral Education might be used in contemporary educational settings by examining primary and secondary sources. Results highlight Integral Educations connection with modern educational techniques and clarify its guiding principles.The study also highlights the advantages, difficulties, and real-world applications of incorporating integral education into a range of educational contexts. The implementation of Integral Education presents a number of problems, including resource allocation, curriculum revision, assessment techniques, teacher preparation, cultural sensitivity, socio-political context, and opposition to change, despite its promise of holistic growth and well-being. To overcome these obstacles, careful preparation, teamwork, and on-going assistance are needed. To sum up, Sri Aurobindos Integral Education Philosophy is a revolutionary approach to learning that gives insightful guidance for developing well-rounded people who can successfully navigate a complex and interrelated world in a variety of educational settings.
Consumo voluntario de etanol y comportamiento ansioso en Ratas Wistar-Uis
Authors: T Mendoza Elizabeth , Villada María , Velasquez Martinez Maria Carolina
Published: May 2024

El consumo de alcohol se encuentra dentro de las primeras cinco sustancias con mayor riesgo asociado con enfermedades, discapacidad y muerte en el mundo. El comportamiento ansioso se ha relacionado con la conductaadictiva al alcohol. El objetivo del presente estudio fue evaluar tres cepas con conductas de ansiedad diferenciales: una cepa normal; una cepa “Reactiva”, con aumento de conductas ansiosas; y una cepa “No-Reactiva”, conmenor comportamiento ansioso, antes y después del protocolo de consumo voluntario de etanol (10%). Para evaluar la ansiedad, los animales fueron expuestos al laberinto en cruz elevado 24 h antes y después del protocolo de consumo. En el protocolo de consumo voluntario de etanol, los animales fueron expuestos a una botella de agua y a una de etanol. Se registró elpeso del líquido consumido durante 40 días. Resultados: todas las cepas aumentaron el consumo de alcohol vs agua: General: día 8; R: día 10; NR: día 31. El consumo de etanol redujo el número y el porcentaje de entradas debrazos abiertos solo en la cepa General. Conclusión: los niveles de ansiedad pueden predisponer a un aumento del consumo de etanol y mantenimiento de comportamientos relacionados con la ansiedad.
Impact of meme marketing on consumer purchase intention: Examining the mediating role of consumer engagement
Authors: Rathi Navrang , Jain Pooja
Published: May 2024

This paper analyzes an emerging form of social media marketing, meme marketing, which has gained attention for its ability to entertain and engage users. Marketers and companies are recognizing the value of using memes as a tool to connect with consumers. To understand the effects of meme marketing activities, this paper aims to examine the impact of meme marketing activities on consumer purchase intentions and concurrently assess the mediating role of consumer engagement. The study encompassed 452 Indian social media users with active social media accounts and familiarity with memes and meme marketing concepts. It employed a quantitative methodology backed by robust statistical techniques. The method used for analysis was Structural Equation Modeling (SEM) through Analysis of Moment Structures (AMOS) software. The results found that meme marketing activities have a direct and significant positive impact (β = 0.257, p < 0.05) on consumer purchase intentions. It further shows that meme marketing has a direct and significant positive impact (β = 0.745, p < 0.05) on consumer engagement. It shows that consumer engagement has a direct and significant positive effect (β = 0.651, p < 0.05) on consumer purchase intention. However, the indirect impact of meme marketing activities on consumer purchase intentions is also significant, resulting in partial mediation. The study findings hold value for marketing managers, agencies, and companies that interact and engage consumers with memes and undertake meme marketing activities.
Polyphenolic content, phytochemical profile composition, and bioactive properties of Castilla Rose (Purshia plicata)
Authors: Gómez Macías Eloisa , Mellado Bosque Miguel Angel , Mellado Bosque Jesus Alberto , Ascacio Valdés Juan Alberto , Martínez Ávila Guillermo Cristian Guadalupe , Nuñez Colima Juan Antonio , Aguilera Carbó Antonio Francisco , Aguilar González Cristobal Noé
Published: May 2024

One of the greatest risks to human and animal health are infectious diseases caused by pathogenic bacteria, as these microorganisms develop mechanisms of resistance to antimicrobials, as a consequence of the indiscriminate and prolonged use of antimicrobials. This makes the treatment of infectious diseases increasingly difficult, in addition to an increase in treatment costs. These disadvantages have led to the search for alternative therapies based on bioactive compounds such as tannins, and flavonoids. Thus, some plant-derived compounds have been used to counteract infectious diseases and other health disorders.  This study aimed to identify polyphenols of purified extract from Purshia plicata, and evaluate the antioxidant potential and the response of in vitro antibacterial activity against pathogen microorganisms of clinical importance for humans and animals.  An aqueous extraction was performed and the compounds were purified using liquid chromatography. The total polyphenolic content was measured employing the Folin Ciocalteu and butanol-HCI methods. The polyphenolic profile was identified by HPLC/ESI/MS. These compounds were screened for in vitro antibacterial activity using the agar diffusion method and antioxidant activity was determined by ABTS•+, DPPH•, and FRAP methods. The compounds showed effectiveness against Klebsiella sp, Escherichia coli, and Salmonella sp, and moderate inhibition against Staphylococcus aureus. The total hydrolyzable polyphenols content was 45.7 mg g-1; the total condensed polyphenols content was 27 mg g-1. The results of the antioxidant activity showed that IC50 was reached at 150 µgml-1, 250 µgml-1, and 150 µgml-1. Twelve compounds were identified by HPCL/ESI/MS, the most important being anthocyanins and ellagitannins. The polyphenolic compounds of P. plicata have the potential to be used as pharmacological products with antibacterial and antioxidant properties for the treatment of infectious diseases in animals and humans.
Vulnerabilidades bancarias/financieras en adultos mayores en México y propuesta de mejores prácticas
Authors: Amador-Licona Norma , Guízar-Mendoza Juan Manuel
Published: May 2024

La pandemia por la COVID-19, propició la obligatoriedad de la inclusión financiera de los adultos mayores, población cada vez más creciente a nivel mundial. Sin embargo, existe la necesidad de implementar políticas públicas, que garanticen la seguridad y eficiencia para la inclusión financiera de este grupo por las dificultades para manejar la banca electrónica. El objetivo de este estudio fue identificar la situación de abuso financiero en México y las estrategias tanto nacionales como internacionales que se han propuesto o implementado para su atención. Se efectuó un estudio de revisión con búsqueda de la información en plataformas como Google académico, PubMed y EBSCO tanto en español como en inglés con las siguientes palabras clave: abuso financiero en adultos mayores, abuso en ancianos, financial abuse in elderly, elder abuse, financial exploitation y protection for financial abuse in elderly, además de la Comisión Nacional para la Protección y Defensa de los Usuarios de Servicios Financieros (CONDUSEF) y el Buró de Entidades Financieras. Como resultados, se presenta una comparación de las reclamaciones de las principales organizaciones financieras en México (2021-2022), se identifican los principales riesgos financieros y se proponen alternativas para mejorar la seguridad en adultos mayores en este rubro.
Choline Based Surfactants Promote Cellular Uptake of Solid Lipid Nanoparticles into Lung and Breast Cancer Cells
Authors: Saadat Maryam , Jafari Sevda , Mahmoudian Mohammad , Sarfraz Muhammad , Khaleseh Farnaz , Zakeri-Milani Parvin , Shahbazi-Mojarrad Javid , Valizadeh Hadi
Published: May 2024

Aims:

The aim of this study was to synthesize two positively charged surfactants
Stearoylcholine and Oleoylcholine from choline or vitamin B4, saturated and mono-unsaturated
fatty acids to modify solid lipid nanoparticles (SLNs) in order to enhance cancer cell uptake.

Methods:

These surfactants were synthesized by using the esterification method and then SLN
formulations of unmodified and modified SLNs containing docetaxel were prepared by emulsification
technique. Cytotoxicity of the SLNs was investigated in A549 and MCF7 cancer cells
and their cell uptake was assessed by using fluorescent microscope and flow cytometry

Results:

The results of our study revealed that SLNs pose a mean particle size range of 69-133
nm with spherical morphology. In vitro release study demonstrated a slow-release pattern for all
three kinds of DTX-loaded SLNs. Stearoylcholine-containing SLNs showed the highest cytotoxic
effect on both cells while cytotoxicity of Oleoylcholine SLNs exhibited a dose-dependent
manner which may be due to the effect of saturated and mono-unsaturated parts of surfactants.
According to flow cytometric analysis, OC and SC containing SLNs showed the highest uptake
into A549 and MCF7 cells, respectively.

Conclusion:

In conclusion, choline-based surfactants could effectively increase the A549 and
MCF7 uptake of modified SLNs, which may be due to cationic surface, choline transporters, and
special receptors and mediators.
A Quality By Design (QbD) Prospect in Fabrication of PLGA-based
Antipsychotic Long-acting Microspheres: An Alternative to Combination
Therapy
Authors: Singh Akanksha , Narkhede Rajkiran , Athawale Rajani
Published: May 2024

Background:

Discontinuation and poor compliance with long-term oral medicine are
major therapeutic issues in psychosis treatment. Poorer long-term outcomes may result from
non-compliance as well as a higher chance of relapse. In order to sustain therapeutic drug plasma
levels, co-administration of oral antipsychotics is necessary for commercially available longacting
injections of second-generation antipsychotics, as they have a lag period of approximately
three weeks during the drug release process.

Methods:

Poly(lactic-co-glycolic acid) (PLGA) encapsulated microspheres loaded with risperidone
were fabricated in the current research for intramuscular administration. The single emulsion
solvent evaporation technique was applied for the fabrication of microspheres. Risperidone
microspheres were prepared using PLGA grade 75:25. Particle size, drug content and entrapment
efficiency with a central composite design were the main optimization parameters for the formulation.
The microspheres were characterized by different techniques, namely Fourier transform
infrared spectroscopy (FT-IR), differential scanning calorimetry (DSC), X-ray diffractometry
(XRD), scanning electron microscopy (SEM), and transmission electron microscopy (TEM). The
drug content, entrapment efficiency, morphology, particle size, and in vitro release profiles,
along with release kinetics of the risperidone microspheres, were studied.

Results and Discussion:

The microspheres produced by the single emulsion solvent evaporation
approach show smooth and spherical morphology, with particle size ranging from 3 μm to 6 μm,
drug content of 99.7%, and entrapment efficiency of 98.2% with little burst release of 3% to
10%, providing drug release for 45 days and exhibiting zero order release kinetics and Korsmeyer-
Peppas model for non-fickian drug release from the polymeric matrix. By applying the Quality
by Design (QbD) approach and formulation parameters, microspheres with appropriate particle
size, morphology, enhanced drug content, entrapment efficiency and desirable drug release
profile for depot formulation can be obtained successfully.

Conclusion:

The optimized microspheres, in comparison to the marketed Risperdal Consta™,
show enhanced potential for a better depot formulation, which can further improve patient compliance.
Exploring the Reality behind Augmented Reality Applications in Retailing: The Role of Value Orientation and Use Frequency
Authors: Al-Sharqi Mais A. , Hasan Haitham S.
Published: May 2024

Background:

Augmented reality (AR) technology has altered the retail business
while also improving the shopping experience. Several studies have been conducted to investigate
the factors that influence the relevance of perceived AR technology values, as well as how
these values influence customer enjoyment and the desire to spread good word of mouth
(WOM). This study explores how the perceived value of AR affects customer satisfaction, enjoyment,
and recommendations.

Objective:

This study aimed to examine how the usage frequency moderates the associations
between human value orientation and perceived AR values, as well as the correlations between
valued AR and satisfaction and positive WOM intention. It studies the relationship between
perceived AR values and consumer happiness, as well as the influence of human value orientation
on perceived AR values (receptivity to change, preservation of resources, selfimprovement,
and transcendence of oneself) (playful, social, aesthetic appeal, and usability).

Methods:

This research extends the human value orientation theory by proposing a novel model
for the link between AR value orientation and usage frequency. To obtain data, a survey was
distributed to those who have engaged with retail AR features.

Results:

Contrary to popular belief, the data demonstrate that a certain group of perceived AR
values is linked to each value orientation, emphasizing the significance of a certain perceived
AR value in affecting customer satisfaction and positive WOM intention. This study shows
that usage frequency moderates the associations between human value orientation and perceived
AR values, as well as the correlations between valued AR and satisfaction and positive
WOM intention. It also shows that consumer value orientation is the most essential aspect in
choosing which AR technology advantage they value most. AR technology values also affect
consumer satisfaction and word-of-mouth marketing (WOM).

Conclusion:

The value orientation of an individual influences the value of augmented reality
technology, which may vary depending on the frequency of usage. This paper concludes with
suggestions for merchants regarding augmented reality technology. Moreover, the precise
number of applications that can be made available to customers and retailers is determined by
this study, which benefits both retailers and researchers.
Graphene-Based Fiber Shape Supercapacitors for Flexible Energy Storage Applications
Authors: Tyagi Ankit , Balasubramaniam Bhuvaneshwari , Gupta Raju Kumar
Published: May 2024

Energy storage devices are essential because of ever-worsening fossil fuel
depletion, increasing energy demand, and increasing environmental pollution. Maxwell
Technologies, NessCap, Ashai Glass, and Panasonic commercialize carbon-based
conventional supercapacitor devices. Carbon materials like graphene, carbon
nanotubes, and activated carbon, are considered favourable materials for bendable and
wearable electronic devices. The graphene, because of its high conductivity (thermal
~5 × 103
W m-1 K-1, electrical ~102
to 108
S m-1), extraordinary surface area
(theoretically ~2630 m2
g-1), outstanding electrochemical performance (100 to 200 F
g
-1), less weight compared to transition metal oxides (because of less molecular weight
of the carbon), outperform every other carbon material [1, 2]. The fiber-shaped
supercapacitors are considered a potential future candidate for electrochemical energy
storage systems and have gained considerable attention from the energy storage
research community. This chapter discusses the importance of fiber-shaped
supercapacitors, their evolution, various forms of their device structures, and
electrolytes used for fiber-shaped supercapacitors. Further, the wet-spinning technique
for synthesizing graphene fibers and their composites with pseudo-capacitive materials
are also discussed.
MXene-based Nanomaterials for Highperformance Supercapacitor Applications
Authors: Babar Zaheer Ud Din , Zaheer Ayesha , Hassan Jahan Zeb , Raza Ali , Mahmood Asif
Published: May 2024

Technological advances in recent decades have augmented the demand for
durable and inexpensive energy storage devices with higher charge capacity. Owing to
their unique charge storage and surface capability, a recent class of two-dimensional
(2D) materials known as MXenes has been widely used in energy storage devices.
MXenes are the layered transition metal carbides, nitrides, and/or carbonitrides
produced via selective etching of interleaved “A” layers from parent MAX phases.
Unlike other 2D materials, MXenes earned great attention because of their intrinsic
surface functional groups, hydrophilicity, unique electrochemical nature, high
conductivity, and superior charge storage capacity. Such features render MXenes as the
ultimate material from the 2D family, thus inspiring researchers to delve further into
experimental and theoretical realms. Numerous attempts have been made to elucidate
synthesis strategies to produce MXene and its fundamental characteristics. The current
chapter emphasizes the recent advancements in MXene-based electrochemical energy
storage applications using supercapacitors which are recognized as a dominant source.
The effect of MXene's morphology and electrode growth on the charge-storage
mechanism has also been highlighted in subsequent sections. In addition, this chapter
outlines the current state-of-the-art on the supercapacitors compromised of the MXenebased composites. A discussion of relevant challenges associated with such materials
for energy storage applications is also presented, and future perspectives provide
additional insight into their practical aspects.
Imidazole and Benzimidazole Derivatives as Anti-Inflammatory Agents
Authors: Dharma Rao G. B. , Versha Bentham Science Publisher , Bendi Anjaneyulu
Published: May 2024

In current days, imidazoles and benzimidazoles are vital classes of Nheterocyclic compounds. One of the 5-membered heterocyclic compounds is imidazole
ring structure through 3 carbon and 2 nitrogen atoms and in imidazole structure, N is
occupied in 1st and 3rd location in five-membered ring system. It is planer in structure.
The imidazole moiety is an essential of numerous significant natural products, together
with histamine, purine, histidine and nucleic acid. On the other hand, benzimidazole
covers six-membered benzene ring system fused with five-member imidazole ring
systems. Benzimidazole core unit molecules continue to be the indispensable focus
among the available heterocyclic compounds because of more than a few
pharmacological and biological properties. Benzimidazoles achieve the center of
attention due to their stability, outstanding bioavailability, and wide range of biological
competence. The current study discloses and discusses the biological activities of
imidazole and benzimidazole scaffolds widely used as anti-inflammatory agents.
Impact of Baseline Characteristics on Stroke Outcomes in Pakistan: A Longitudinal Study Using the Modified Rankin Scale
Authors: Shabbir Muhammad , Alshahrani Abdurrahman M. , Ram Dushad , Liaqat Ambreen , Almarshad Feras M. , Alfaiz Abdulrahman Saad , Alammar Muath A. , Banday Altaf Husain , Israr Muhammad , Sajjad Muhammad Mohsin
Published: May 2024

Introduction. Stroke is a leading cause of disability and mortality globally, with a significant impact on healthcare systems. Various factors, including age, gender, comorbidities, and the type of stroke, influence the burden of stroke and its outcomes.
The study was conducted with an objective to determine the impact of baseline characteristics on the long-term functional outcome of stroke patients.
Methods. This prospective observational study was conducted between April 6, 2022 - December 31, 2023, at a tertiary hospital. The study included patients with radiologically confirmed stroke, selected through convenience sampling. Stroke patients of any gender and all age groups, with any comorbidity, were included. The Modified Rankin Scale (mRS) assessed disability on admission and three months post-stroke.
Results. Of the 213 patients, 122 (57.3%) were males and the majority, 199 (93.4%) individuals, had acute ischemic stroke. The median age of the participants was 60 years (range: 13-97 years; IQR=18 years). The mRS score on admission was poor (5.0; IQR=1.0) for patients ≥ 60 years. In 74 (34.74%) participants, the left middle cerebral artery was a frequently involved site. Age of ≥ 60 years (mRS=4.0; IQR=4.0; p=0.001) and the presence of ≥ 3 comorbidities (mRS=5.0; IQR=1.0; p=0.001) were significantly associated with poor outcomes three months post-stroke. Ordinal logistic regression revealed that a mRS score of 4 (OR=14.20; 95% CI=1.70-145.25; p=0.02) and a mRS score of 5 (OR=78.84; 95% CI=9.35-820.25; p < 0.001) on admission were associated with poor outcomes. In addition, the presence of ≥ 3 comorbidities (OR=4.59; 95% CI=14.65; p < 0.01) and increasing age (OR=1.04; 95% CI=1.01-1.07; p=0.02) were predictors of poor outcomes three months post-stroke.
Conclusions. The study underscores the importance of early intervention and effective management of comorbidities to improve functional outcomes in stroke patients. It highlights the need for targeted stroke care and rehabilitation strategies.
FLOOD VULNERABILITY AND ADAPTATION ASSESSMENT IN PADANG TERAP DISTRICT, KEDAH, MALAYSIA
Authors: Said Mohd Zulhafiz , Abdul Gapor Salfarina , Hamat Zahri
Published: May 2024

Padang Terap, Kedah in Malaysia experienced frequent floods, incurring financial losses to the flood victims and the government for flood mitigation. For an effective mitigation strategy, there is a need for a reliable database on the vulnerability and adaptation levels of flood victims. Therefore, this study is important to provide the data. The objectives of this paper are to analyse the factors that cause flood vulnerability and to determine and assess the existing adaptation to flood in Padang Terap. The research utilised a quantitative approach, through a household survey of 680 respondents. The data were analysed using descriptive and crosstabulation tests. The findings show that topography, distance between houses and rivers, and flood relief centres affect the vulnerability of the flood victims. The vulnerability to flood is higher than the adaptation level, implying that the Padang Terap flood victims are still not adapting to flood and prone to losses incurred related to flood.
ATTRIBUTES AND ACTIVITIES IN PUBLIC URBAN SPACES OF MALAYSIAN CITIES
Authors: Hamzah Maheran , Sinniah Gobi Krishna , Rusli Noradila
Published: May 2024

In contemporary society, urban spaces have emerged as the predominant locale for communal assembly among the general populace. However, a significant deficiency of urban spaces is observed in the majority of metropolitan locations in Malaysia.  This study raises the question of how urban space could promote community space in an urban area while considering activities and site physical attributes. Therefore, this study aims to identify the urban space attributes and activities in two categories of Malaysian cities: new urban areas and historical areas. This study uses cross-comparison and descriptive analysis to derive key attributes of urban spaces, including high walkability, diverse activities, vibrant street art, and green elements. The dominant attributes based on the evaluation were walkability, urban activities, street art, green elements, and aesthetically pleasing historic buildings. Primary activities were walking, photography, and cycling (100%). Predominant urban activities based on evaluation were walking, photographing, and sales booth streets. Sungai Segget Johor Bahru (mix of historical and new urban areas), Melaka Jonker Street (historical town) and River of Life Kuala Lumpur (a mix of historical and new urban areas) have the highest of urban space elements. Therefore, urban activities are highest in historical cities such as Melaka Jonker Street and Penang Street Art. This study provides stakeholders valuable insight into different urban space attributes and activity patterns between cities. By expanding the analysis scope beyond the main capital city in Malaysia and recommending further exploration of additional attributes, this research offers a more nuanced understanding of the interplay between urban space and activities.
CLIMATE RESPONSIVE DESIGN IN HERITAGE STRUCTURE: AN ANALYSIS ON THE DECORATIVE ARCHITECTURAL COMPONENTS DESIGN OF RUMAH LIMAS BUMBUNG PERAK (RLBP)
Authors: Abdul Halim Choo Iryani , Abdul Rashid Mohd Sabrizaa , Jamaludin Nazrul Helmy , Muhammad Afzanizam , Mohd Nor Othman
Published: May 2024

The absence of readily available energy in the past such as electricity has contributed to the indigenous formation of a climate-responsive dwelling structure that harnesses the provided energy from nature. The decorative architectural component is one of the heritage values in traditional Malay house that is not only functional but also symbolic and aesthetic towards the house's heritage architectural character.  The aim of this research is to explore the climatic responsive function of the decorative architectural components of Rumah Limas Bumbung Perak (RLBP). Qualitative research was used as the research approach via case studies. This encompassed field works of site observation conducted on the decorative architectural components observed from the 9 samples of Rumah Limas Bumbung Perak (RLBP) chosen. The analysis was conducted by analysing the design attributes of the decorative architectural components that lead to the research findings. The findings of the research found that the design attributes of the decorative architectural components of RLBP correspond to multiple climatic functions – as a shading and filtering device, ventilation device, and climate protection device that contributes to the climate responsive design of the components. The output from this research not only strengthened the existing findings but also can contribute to the formation of the planning guideline for future housing planning in Malaysia, particularly on the spatial and sustainable quality of modern house design.
MOSQUE TOURISM IN THE DIGITAL AGE: EXAMINING GENERATION Y'S VIRTUAL REALITY EXPERIENCES
Authors: Md Sawari Siti Salwa , Mat Desa Sıtı Nuur Hamızah , Hussin Siti Rahayu , Ab Talib Mohamed Syazwan
Published: May 2024

The rise in Muslim travelers and the swift evolution of virtual reality (VR) technology is fundamentally transforming the global tourism industry. This convergence underscores the immediate need for further academic exploration into the potential uses of virtual reality in the domain of Muslim tourism, creating a promising avenue for future research. In this vein, our study aims to evaluate how Generation Y perceives the concept of participating in virtual reality mosque tourism, considering both cognitive and emotional responses from this demographic's perspective. The primary goal of our research is to uncover Generation Y's genuine experiences in virtual reality mosque tourism. Our quantitative research methodology involved 100 Muslim travelers aged between 29 and 41 years. Data analysis was conducted using the IBM Statistical Package for Social Science (SPSS), encompassing both descriptive and Pearson correlation analyses. The findings of our analysis, which indicate that a significant majority of participants found the 360-degree Virtual Reality Mosque Tour enjoyable and captivating, have significant implications for understanding cognitive and emotional responses related to the intention to visit mosques in the tourism context. These findings could potentially shape the future landscape of mosque tourism, making our research a crucial contribution to the field.
Analisis Keuangan Terhadap Penyaluran Dana Tepat Guna Dalam Sebuah Kredit
Authors: Saputra Andrian
Published: May 2024

This research is about the accuracy of funds in credit. Indicators related and contextually related to giving, include the principles of moral trust, commercial principles, financial and collateral principles. The research method uses a library research approach. Credit in the general context, bank considerations in channeling funds, targets and objectives in providing credit funds. Credit actually gives and disposes of various funds that were originally collected through various deposits, whether in the form of current accounts, savings or through deposits. The purpose of credit is more simply, aimed at getting benefits in the form of interest as a form of feedback from the process of giving. The distribution of credit funds that are right on target will have a major impact on the development of the economic sector. This is if the credit is given to whom and who actually needs financial support in starting and starting the economy. So when credit funds are given, for example, to movers and activists in the MSME sector if they need these funds in building their business. Accuracy and distribution of funds that are right on target will produce a very significant effect in the context of financial institutions such as banking and the economy in Indonesia.

 

 
Analisis Pembentukan Portofolio Optimal Pada Saham Yang Masuk Dalam Indeks Badan Usaha Milik Negara 20 (BUMN20)
Authors: Islami Inggrid Claudia , Mas’ud Arifuddin , Kalsum Ummy
Published: May 2024

Tujuan dari penelitian ini adalah bagaimana menganalisis pembentukan portofolio optimal dengan model indeks tunggal pada saham yang masuk dalam Indeks Badan Usaha Milik Negara 20 selama periode Agustus 2018-Juli 2023 dengan mengukur return dan risiko yang terbentuk. Rancangan penelitian ini adalah penelitian deskirptif kuantitatif. Menggunakan populasi sebanyan 26 perusahaan yang masuk dalam indeks Badan Usaha Milik Negara 20 selama periode Agutsus 2018 – Juli 2023 dengan menggunakan sampel sebanyak 15 perusahaan yang masuk dalam indeks Badan Usaha Milik Negara 20 selama lima tahun berturut-turut. Metode analisis data yang digunakan adalah model indeks tunggal. Hasil penelitian menunjukkan bahwa portofolio optimal yang terbentuk terdiri dari sampel 15 perusahaan Badan Usaha Milik Negara tersisa 10 perusahaan yakni, ANTM, BBNI, BBRI, BMRI, ELSA, PGAS, PTBA, SMGR, TINS, TLKM dengan return portofolio sebesar 1,40% dan risiko 0,12%. Kesimpulan pada penelitian ini adalah pembentukkan portofolio dengan saham-saham yang optimal dapat mengurangi risiko yang mungkin ditanggung oleh investor dan return yang dihasilkan.
Personalized Skincare: Correlating Genetics with Skin Phenotypes through DNA Analysis
Authors: Akbar Sirwan Aziz , Hassan Shkar M J , Raoof Zana Muhamad , Saeed Mudhafar Mohamed M.
Published: May 2024

Genetic mapping through DNA sequencing for skin represents a novel method to elucidate detailed information regarding the relationship between genes and skin. This method analyzes genetic influences on various skin characteristics, crucial in the skin aging process. In this study, we aimed to explore the efficacy and potential of skin DNA sequencing as a valuable tool in dermatological research. Employing a purposive sampling method based on diverse skin types, we sought to ensure representativeness within the target population. The sample comprised four different skin types (five participants), selected to encompass a wide range of ages and diverse racial backgrounds. We precisely controlled for potential confounding factors such as age, gender, and race in study design. All participants exhibited consistent Fitzpatrick skin type classifications based on questionnaire responses and measurements from the Automatic Plasma Skin Type Analyzer or melanin reader. This consistency underscores the reliability of the Fitzpatrick skin type classification technique for determining skin phenotypes. Such classification holds significant importance in clinical research, guiding professionals and consumers in selecting suitable cosmetic products and skincare regimens. Furthermore, our study investigated into participants’ skin characteristics and their genetic predispositions to various skin-related attributes including dermal sensitivity, protection against glycation, antioxidant capacity, freckles, and cellulite. DNA skin tests offer critical insights into understanding and managing one’s unique skin traits. Our findings highlight the substantial impact of genetics on skin attributes. Notably, our observations indicate that individuals with similar skin types may harbor distinct genetic predispositions, underscoring the necessity for personalized skincare approaches. The results aim to empower clients, dermatologists, and beauty consultants to make knowledgeable skincare decisions based on genetic factors. The reliability of the Fitzpatrick skin type classification technique was validated through both questionnaire-based assessments and measurements from the Automatic Plasma Skin Type Analyzer or melanin reader, affirming its consistency and accuracy in describing participants’ skin phenotypes. In summary, our study contributes to a deeper understanding of skin health and equips individuals, dermatologists, and beauty consultants to make knowledgeable skincare choices based on genetic insights.