bluuebunny/crossref_metadata_2025 huggingface dataset:
The Rare-Earth Elements
Authors: Aslan Mikail , Bozada Cengiz
Published: January 2023

In this section, the elemental forms of rare-earth elements are iron gray to
silvery lustrous metals that are typically soft, malleable, ductile, and usually reactive,
especially at elevated temperatures or when finely divided. rare-earth elements are
examined in terms of physical and chemical properties. This makes them essential
components of diverse defense, energy, industrial, military technology, and low-carbon
technologies. Furthermore, REEs are rapidly being used in magnet applications. For
example, magnets produced by Neodymium-iron, the strongest known type of magnet,
are used widely. Thus, their application areas vary from the electronic to glass industry.
Also, information about the sources of rare-earth elements is given in this part.
The Rare-Earth Hexaborides
Authors: Aslan Mikail , Bozada Cengiz
Published: January 2023

Rare-earth hexaborides (REB6
) are composed of rare-earth elements and
octahedral 3D boron units. In Chapter 1, rare-earth elements were examined in detail;
in this part, the REB6
will be explained. Hence, rare-earth hexaborides (REB6
)
consisting of rare-earth elements and octahedral bor units are a group of ceramic
materials that have a simple cubic structure with Pm3m symmetry. Their low electronic
work function, low electrical resistance, and thermal expansion coefficient (in some
temperature ranges), as well as high hardness and stiffness, high chemical and thermal
stability, and melting points, provide a wide range of industrial uses from metallurgy to
electronics.
Figure Correction", “Effectiveness of Secondary Risk–Reducing Strategies in Patients With Unilateral Breast Cancer With Pathogenic Variants of BRCA1 and BRCA2 Subjected to Breast-Conserving Surgery: Evidence-Based Simulation Study” (Preprint)
Authors: Maksimenko Jelena
Published: January 2023

UNSTRUCTURED

Correction: Effectiveness of Secondary Risk–Reducing Strategies in Patients With Unilateral Breast Cancer With Pathogenic Variants of BRCA1 and BRCA2 Subjected to Breast-Conserving Surgery: Evidence-Based Simulation Study

In “Effectiveness of Secondary Risk–Reducing Strategies in Patients With Unilateral Breast Cancer With Pathogenic Variants of BRCA1 and BRCA2 Subjected to Breast-Conserving Surgery: Evidence-Based Simulation Study” (JMIR Form Res. 2022 Dec 29;6(12):e37144. doi: 10.2196/37144.) the authors noted one error.
Appeal of Editor-in-Chief
Authors: Ivanov D.D.
Published: January 2023

No abstract
Efficacy and safety of urate-lowering therapy in multimorbid patients in real clinical practice: results of clinical study
Authors: Khimion L.V. , Nayshtetik I.M. , Burianov O.A. , Rotova S.O. , Smyian S.I. , Lapshyna H.M. , Danyliuk S.V. , Sytiuk T.O. , Kicha N.V. , Lebedeva T.O. , Trofanchuk V.V.
Published: January 2023

Background. Clinical studies of urate-lowering therapy (ULT) use in multimorbid patients, including those with chronic kidney disease (CKD), are important in modern medical science. The purpose was to determine the efficacy and safety of ULT in patients with hyperuricemia and comorbid conditions, including people with chronic kidney disease, in real clinical practice. Materials and methods. This prospective comparative clinical study “Liquestia: comparative efficacy and safety in gouty arthritis patients with comorbid diseases and in patients with hyperuricemia and chronic kidney disease” was conducted in real clinical practice with the involvement of 124 patients with hyperuricemia, who were prescribed either febuxostat (Liquestia, JSC “Farmak”/Adenuric, Berlin Chemie) or allopurinol as ULT. Results. Individuals who received febuxostat significantly more often and faster reached the target levels of uric acid compared to patients who underwent treatment by allopurinol, regardless of glomerular filtration rate (GFR), except those from dialysis subgroup, and the presence of comorbidities. Patients in febuxostat subgroups during the study showed an increase in GFR after 6 months of treatment — at the level of the trend in the group with baseline GFR ≥ 60 ml/min and at a statistically significant level — in CKD stage 3–4, which could be the evidence of renoprotective effect of febuxostat with reduced GFR, while people receiving allopurinol tended to further decrease of GFR in 31.8 % of cases. Conclusions. The use of Liquestia for the treatment of patients with hyperuricemia and various comorbid conditions is no less effective than the use of Adenuric and more effective than allopurinol and helps achieve the target levels of uric acid in 90 % of cases within 6 months of treatment, which accompanied by a statistically significant increase in GFR in patients with CKD stage 3–4.
Professor D. Ivanov’s report at the KfH-Symposium Nephrologie & Rezertifizierung für Hypertensiologeninnen DHL® 19 (November, 2022, online-seminar)
Authors: Ivanov D.D.
Published: January 2023

No abstract
Executive summary of the KDIGO 2022 Clinical Practice Guideline for Diabetes Management in Chronic Kidney Disease: an update based on rapidly emerging new evidence
Authors: Rossing Peter , Caramori M. Luiza , Chan Juliana C.N. , Al. Et
Published: January 2023

No abstract
Gabapentin, Concomitant Prescription of Opioids, and Benzodiazepines among Kidney Transplant Recipients
Authors: Chen Yusi , Ahn JiYoon B. , Bae Sunjae , Joseph Corey , Schnitzler Mark , Hess Gregory P. , Lentine Krista L. , Lonze Bonnie E. , Segev Dorry L. , McAdams-DeMarco Mara
Published: January 2023

Background

Gabapentinoids, commonly used for treating neuropathic pain, may be misused and coprescribed with opioid and benzodiazepine, increasing the risk of mortality and dependency among kidney transplant recipients.

Methods

We identified adult kidney transplant recipients who enrolled in Medicare Part D in 2006–2017 using the United States Renal Data System/Medicare claims database. We characterized recipients' post-transplant concomitant prescription of gabapentinoids, opioids, and benzodiazepine stratified by transplant year and recipient factors (age, sex, race, and diabetes). We investigated whether concomitant prescriptions were associated with postkidney transplant mortality using Cox regression. Models incorporated inverse probability weighting to adjust for confounders.

Results

Among 63,359 eligible recipients, 13% of recipients filled at least one gabapentinoid prescription within 1 year after kidney transplant. The prevalence of gabapentinoid prescriptions increased by 70% over the study period (16% in 2017 versus 10% in 2006). Compared with nonusers, gabapentinoids users were more likely to have diabetes (55% versus 37%) and obesity (46% versus 34%). Of the 8509 recipients with gabapentinoid prescriptions, 45% were coprescribed opioids, 7% were coprescribed benzodiazepines, and 3% were coprescribed both opioids and benzodiazepines. Compared with no study prescriptions, gabapentinoid monotherapy (adjusted hazard ratio [aHR]=1.25; 95% confidence interval [CI], 1.16 to 1.32) and combination therapy (gabapentinoids and opioids [aHR=1.49; 95% CI, 1.39 to 1.60], gabapentinoids and benzodiazepines [aHR=1.46; 95% CI, 1.03 to 2.08], and coprescribing all three [aHR=1.88; 95% CI, 1.18 to 2.98]) were all associated with a higher risk of postkidney transplant mortality.

Conclusions

Gabapentinoid coprescription with both benzodiazepines and opioids among kidney transplant recipients increased over time. Kidney transplant recipients prescribed gabapentinoids had a higher risk of post-transplant mortality, and the risk was higher with opioids or benzodiazepine coprescription.
Development of a Patient-Reported Outcomes Tool to Assess Pain and Discomfort in Autosomal Dominant Polycystic Kidney Disease
Authors: Oberdhan Dorothee , Cole Jason C. , Atkinson Mark J. , Krasa Holly B. , Davison Sara N. , Perrone Ronald D.
Published: January 2023

Background

Pain has been identified as a core outcome for individuals with autosomal dominant polycystic kidney disease (ADPKD), but no disease-specific pain assessment has been developed using current development methodology for patient-reported outcomes (PRO) instruments. We developed and validated an ADPKD-specific pain questionnaire: the ADPKD Pain and Discomfort Scale (ADPKD-PDS).

Methods

Conceptual underpinnings were drawn from literature review, concept elicitation, expert consultation, and measurement performance. In the qualitative analysis phase, concepts were elicited from focus groups of adults with ADPKD, and the resulting draft instrument was refined using cognitive debriefing interviews with individuals with ADPKD. For quantitative analysis, adults with ADPKD completed the draft instrument and other PRO tools in an online survey, and a follow-up survey was conducted 3–4 weeks later. Survey responses were analyzed for item-level descriptive statistics, latent model fit statistics, item discrimination, item- and domain-level psychometric statistics, test-retest reliability, responsiveness to change, and convergent validity.

Results

In the qualitative phase, 46 focus groups were conducted in 18 countries with 293 participants. Focus groups described three conceptually distinct types of ADPKD-related pain and discomfort (dull kidney pain, sharp kidney pain, and fullness/discomfort). In the quantitative phase, 298 adults with ADPKD completed the online survey, and 108 participants completed the follow-up survey. After iterative refinement of the instrument, latent variable measurement models showed very good fit (comparative fit and nonnormed fit indices both 0.99), as did item- and domain-level psychometric characteristics. The final ADPKD-PDS contains 20 items assessing pain severity and interference with activities over a 7-day recall period.

Conclusions

The ADPKD-PDS is the first validated tool for systematically assessing pain and discomfort in ADPKD.
A Health Survey–Based Prediction Equation for Incident CKD
Authors: Noel Ariana J. , Eddeen Anan Badder , Manuel Douglas G. , Rhodes Emily , Tangri Navdeep , Hundemer Gregory L. , Tanuseputro Peter , Knoll Gregory A. , Mallick Ranjeeta , Sood Manish M.
Published: January 2023

Background

Prediction tools that incorporate self-reported health information could increase CKD awareness, identify modifiable lifestyle risk factors, and prevent disease. We developed and validated a survey-based prediction equation to identify individuals at risk for incident CKD (eGFR <60 ml/min per 1.73 m2), with and without a baseline eGFR.

Methods

A cohort of adults with an eGFR ≥70 ml/min per 1.73 m2 from Ontario, Canada, who completed a comprehensive general population health survey between 2000 and 2015 were included (n=22,200). Prediction equations included demographics (age, sex), comorbidities, lifestyle factors, diet, and mood. Models with and without baseline eGFR were derived and externally validated in the UK Biobank (n=15,522). New-onset CKD (eGFR <60 ml/min per 1.73 m2) with ≤8 years of follow-up was the primary outcome.

Results

Among Ontario individuals (mean age, 55 years; 58% women; baseline eGFR, 95 (SD 15) ml/min per 1.73 m2), new-onset CKD occurred in 1981 (9%) during a median follow-up time of 4.2 years. The final models included lifestyle factors (smoking, alcohol, physical activity) and comorbid illnesses (diabetes, hypertension, cancer). The model was discriminating in individuals with and without a baseline eGFR measure (5-year c-statistic with baseline eGFR: 83.5, 95% confidence interval [CI], 82.2 to 84.9; without: 81.0, 95% CI, 79.8 to 82.4) and well calibrated. In external validation, the 5-year c-statistic was 78.1 (95% CI, 74.2 to 82.0) and 66.0 (95% CI, 61.6 to 70.4), with and without baseline eGFR, respectively, and maintained calibration.

Conclusions

Self-reported lifestyle and health behavior information from health surveys may aid in predicting incident CKD.

Podcast

This article contains a podcast at https://dts.podtrac.com/redirect.mp3/www.asn-online.org/media/podcast/CJASN/2023_01_10_CJN0000000000000035.mp3
Debate: Intermittent Hemodialysis versus Continuous Kidney Replacement Therapy in the Critically Ill Patient: The Argument for CKRT
Authors: Bagshaw Sean M. , Neyra Javier A. , Tolwani Ashita J. , Wald Ron
Published: January 2023

Continuous kidney replacement therapy (CKRT) is well entrenched as one of the dominant KRT modalities in modern critical care practice. Since its introduction four decades ago, there have been considerable innovations in CKRT machines that have improved precision, safety, and simplicity. CKRT is the preferred KRT modality for critically ill patients with hemodynamic instability. Early physical therapy and rehabilitation can be feasibly and safely provided to patients connected to CKRT, thus obviating concerns about immobility. Although randomized clinical trials have not shown a mortality difference when comparing CKRT and intermittent hemodialysis, CKRT allows precision delivery of solute and fluid removal that can be readily adjusted in the face of dynamic circumstances. Accumulated evidence from observational studies, although susceptible to bias, has shown that CKRT, when compared with intermittent hemodialysis, is associated with better short- and long-term kidney recovery and KRT independence. Critical care medicine encompasses a wide range of sick patients, and no single KRT modality is likely to ideally suit every patient in every context and for every condition. The provision of KRT represents a spectrum of modalities to which patients can flexibly transition in response to their evolving condition. As a vital tool for organ support in the intensive care unit, CKRT enables the personalization of KRT to meet the clinical demands of patients during the most severe phases of their illness.
Dialysis in Israeli Children between 1990 and 2020: Trends and International Comparisons
Authors: Regev-Epstein Lilach C. , Frishberg Yaacov , Davidovits Miriam , Landau Daniel , Magen Daniella , Weismann Irit , Stern-Zimmer Michal , Beckerman Pazit , Keinan-Boker Lital , Calderon-Margalit Ronit , Vivante Asaf
Published: January 2023

Background

Childhood kidney failure is a rare condition with worldwide clinical variability. We used a nationwide multicenter analysis to study the pretransplant course of the entire Israeli pediatric kidney failure population over 30 years.

Methods

In this nationwide, population-based, historical cohort study, we analyzed medical and demographic data of all children treated with KRT and reported to the Israeli kidney failure registry in 1990–2020. Statistical analysis was performed with incidence rate corrected for age, ethnicity, and calendar year, using the appropriate age-related general population as denominator.

Results

During the last 30 years, childhood incidence of kidney failure decreased. Average incidence in 2015–2019 was 9.1 cases per million age-related population (pmarp). Arab and Druze children exhibited higher kidney failure incidence rates than Jewish children (18.4 versus 7.0 cases pmarp for minorities versus Jews). The most common kidney failure etiologies among Arab and Jewish children were congenital anomalies of the kidney and urinary tract (approximately 27%), followed by cystic kidney diseases among Arab children (13%) and glomerulonephritis among Jewish children (16%). The most common etiology among Druze children was primary hyperoxaluria type 1 (33%). Israel's national health insurance provides access to primary health care to all citizens. Accordingly, waiting time for deceased-donor transplantation was equal between all ethnicities. Living-donor kidney transplantation rates among minority populations remained low in comparison with Jews over the entire study period. Although all patient groups demonstrated improvement in survival, overall survival rates were mainly etiology dependent.

Conclusions

In Israel, Arab and Druze children had a higher incidence of kidney failure, a unique etiological distribution, and a lower rate of living-donor kidney transplantations compared with Jewish children.
Cardiorenal Syndrome in the Hospital
Authors: McCallum Wendy , Sarnak Mark J.
Published: January 2023

The cardiorenal syndrome refers to a group of complex, bidirectional pathophysiological pathways involving dysfunction in both the heart and kidney. Upward of 60% of patients admitted for acute decompensated heart failure have CKD, as defined by an eGFR of <60 ml/min per 1.73 m2. CKD, in turn, is one of the strongest risk factors for mortality and cardiovascular events in acute decompensated heart failure. Although not well understood, the mechanisms in the cardiorenal syndrome include venous congestion, arterial underfilling, neurohormonal activation, inflammation, and endothelial dysfunction. Arterial underfilling may lead to activation of the renin-angiotensin-aldosterone system and sympathetic nervous system, leading to sodium reabsorption and vasoconstriction. Venous congestion likely also mediates and perpetuates these maladaptive pathways. To rule out intrinsic kidney disease that is distinct from the cardiorenal syndrome, one should obtain a careful history, review longitudinal eGFR trends, assess albuminuria and proteinuria, and review the urine sediment and kidney imaging. The hallmark of the cardiorenal syndrome is intense sodium avidity and diuretic resistance, often requiring a combination of diuretics with varying pharmacological targets, and monitoring of urinary response to guide escalations in therapy. Invasive means of decongestion may be required including ultrafiltration or KRT such as peritoneal dialysis, which is often better tolerated from a hemodynamic perspective than intermittent hemodialysis. Strategies for increasing forward perfusion in states of low cardiac output and cardiogenic shock may include afterload reduction and inotropes and, in the most severe cases, mechanical circulatory support devices, many of which have kidney-specific considerations.
A Case Study of Educational Equity in Saskatchewan Schools and Implications for Educational Development in China
Authors: Jin Ruining , Wang Xiao , Zhao Lianghu
Published: January 2023

This paper probes the phenomenon of underperforming indigenous students in Canada through a case study in the school district of Saskatchewan. It is discerned that the disparity between indigenous students’ home culture and the mainstream classroom culture is the major obstacle between indigenous students and academic success. Such a disparity is caused by a couple of reasons. First of all, educators’ misconception, along with education decision-makers’ ineffectiveness, leads to adversity for indigenous students to face in the classroom; secondly, biased evaluation and misjudgments in the current education system also result in indigenous students’ underperformance. Lastly, educators’ low cultural proficiency towards indigenous culture culminates in indigenous students’ low classroom engagement. The results of the case study could be enlightening for Chinese education decision-makers, given that the Chinese booming economy has caused millions of internal migrant workers to work in an alien subculture, their children could face similar social and linguistic debacles as compared to indigenous students in Saskatchewan.
Research on the Construction of Postgraduate Academic Morality
Authors: Fu Han , Tiansheng Zuo
Published: January 2023

The construction of postgraduate academic morality is a problem that all postgraduates must face. There are some problems in the construction of postgraduate academic morality, such as insufficient academic integrity, insufficient academic norms and insufficient academic spirit. After analyzing the reasons of academic morality, academic evaluation, academic supervision and academic self-discipline, the academic morality of postgraduates is promoted to develop deeper, broader and more comprehensive. We must strengthen moral education, improve the evaluation system, strengthen moral supervision, cultivate moral self-discipline, and strictly punish the system to improve the academic moral level of graduate students.
Pay Attention to the Brand Building of Jewelry Industry to Promote the Healthy Development of the Industry
Authors: Liu Yuxin
Published: January 2023

In recent years, the speed of domestic economic development has gradually accelerated, leading the people to pay more attention to the material and spiritual enjoyment. As a part of residents' life, jewelry itself plays a very significant role in the development of human history, making the domestic jewelry industry relatively broad. However, on the other hand, the domestic jewelry industry presents an extensive growth trend in the development, and the management effect is weak, and there is no enough quality brand established. Practitioners in the jewelry industry gradually realize the influence of brand on the jewelry industry, and try to use brand building to drive the healthy development of the industry.
IoT Based Smart Crop Monitoring System
Authors: Rishish A. , Sudhanshu G. , Akshay P. , Srinivasulu Dr. Y.
Published: January 2023

Abstract: Advances must also be made in the field of agriculture as new technologies are introduced and used in the modern world. Various studies have been conducted and are widely used to improve the cultivation of crops. Environmental conditions in and around the field must be monitored to effectively improve crop productivity. Parameters that need to be properly monitored to increase yields include soil properties, weather conditions, humidity and temperature. The Internet of Things (IOT) is used in several real-time applications. The introduction of IOT along with sensor networks in agriculture will change the traditional way of farming. Online crop monitoring via IOT helps farmers connect to their fields anytime, anywhere. Various sensors are used to monitor and collect information about the condition of the field.
UJI JENIS PENAMPUNG DAN BAHAN PENGGUMPAL LATEKS BERBAHAN BAKU SISA PRODUKSI PERTANIAN ASAM GELUGUR DAN NANAS BAGI KARET RAKYAT
Authors: HUTAPEA Sumihar , Siregar Tumpal , INDRAWATY Asmah
Published: January 2023

Rendahnya mutu bahan olah karet rakyat (bokar) antara lain disebabkan rendahnya penanganan pasca panen, seperti wadah penampung lateks yang sembarangan, penggumpal lateks yang tidak bermutu, dan belum memenuhi syarat. Faktor penampung lateks dan bahan penggumpal dinilai sebagai faktor utama penyebabnya. Untuk mengatasinya, perlu dilakukan penelitian yang berhubungan dengan penampung lateks, bahan penggumpal, dan teknik penanganan bokar. Penelitian ini bertujuan untuk mengatasi mutu bokar yang rendah. Penelitian dilakukan pada kebun karet rakyat di desa Sari Laba Jahe (Kecamatan Sibirubiru, Deli Serdang, Sumatra Utara). Desa tersebut merupakan penghasil asam gelugur dan nanas. Penelitian dilakukan dengan menguji 3 jenis penampung lateks (penampung lateks standar, ruas bambu, dan tempurung kelapa), dan empat jenis bahan penggumpal (ekstrak asam gelugur, ekstrak nanas, asam semut, dan pupuk TSP). Kombinasi dari kedua bahan tersebut diulang sebanyak 3 kali. Hasil dalam bentuk bokar kemudian dijepit pada media anyaman bambu, masing-masing selama 2, 4, dan 6 hari. Pengamatan meliputi berat bokar dan kadar karet kering (KKK). Hasil penelitian menunjukkan bahwa penampung lateks standar merupakan penampung lateks terbaik untuk menghasilkan berat bokar tertinggi. Sedangkan penggumpal ekstrak asam gelugur dan ekstrak nanas dengan masa penyimpanan 6 hari menghasilkan bokar dengan KKK tertinggi, yakni > 70%.
Linguistic Peculiarities of Bullying in Georgian and American School Discourse
Authors:   Batumi State University, Georgia, Shavadze Roland , Goshkheteliani Irine ,   Batumi State University, Georgia, Mikeladze Madona ,   Batumi State University, Georgia
Published: January 2023

Many scholars have investigated bullying as a social problem in educational institutions. However, just a few scientific works are available attempting to offer the analysis of the linguistic peculiarities related to bullying in school discourse. Since bullying is a violative act expressed verbally or physically to intimidate members of particular society, it is important to consider the linguistic features directly related to the language used by aggressors to harm victims. Consequently, in the present paper, we will explore certain verbal register (words, phrases, linguistic patterns, etc.) generally used by aggressors to insult, threaten or harm victims.
AFRICAN REGIONAL AND INTERNATIONAL COORDINATION: HOW COVID-19 ADVANCED INTEGRATION TRENDS AND SOUTH-SOUTH COOPERATION
Authors: Castro Kowalski Camila , Bonacina Amabilly
Published: January 2023

Africa is one of the world's forerunners in terms of political integration. Already in the 1960s, the Organisation of African Unity had 32 states united under a common charter. Moreover, through joint projects with Latin American and Asian partners, African states have joined some of the primary experiences of South-South Cooperation, particularly in the areas of healthcare and infrastructure. Taking this historical context into account, this paper examines how the highly competitive reality of the COVID-19 pandemic has impacted the continent. We argue that the constraints imposed by the new coronavirus outbreak have strengthened the African Union's role in advancing collective action and encouraged self-sufficiency. Furthermore, we analyse how South-South Cooperation offered a platform for immediate response when access to disputed medical supplies in the world market was difficult. We conclude that the COVID-19 crisis has contributed to consolidating African regional integration in the long-term, as well as its coordination with partner emerging countries, with consequences for the African Union’s priorities in terms of foreign affairs in the future.
O PERCURSO METODOLÓGICO DE UMA PESQUISA QUALITATIVA: NA LINHA DA FENOMENOLOGIA E DA HISTORIOGRAFIA.
Authors: Salgueiro Melo Juliana , Almeida Carvalho Cristianne
Published: January 2023

Este trabalho visa apresentar a trajetória de uma pesquisa qualitativa em Psicologia, que defini a Fenomenologia e a Historiografia como metodologias. Após delimitar os objetivos da pesquisa em questão, fez-se necessário elaborar um percurso metodológico para alcançá-los. Dessa forma, inicia-se o relato de uma longa jornada que envolve desde a delimitação do universo da pesquisa até os passos da pesquisadora em campo. Este artigo tem como propósito partilhar informações, discutir e minimizar as dificuldades enfrentadas por pesquisadores em trabalho de campo no uso de metodologias de base qualitativa, especificamente a historiografia e a Fenomenologia no método proposto por Amadeo Giorgi e Daniel Sousa. Assim, organiza-se o presente trabalho da seguinte forma: introdução, que recupera a história da pesquisa realizada; percurso metodológico: primeiras pistas; escolha dos participantes, fundamentos metodológicos, passo a passo da pesquisa em campo e considerações finais.
BREVE ENSAIO GENEALÓGICO SOBRE O CURRÍCULO DO ENSINO MÉDIO INTEGRADO
Authors: Pereira Reginaldo Santos , Da Silva Pimentel Carvalho Judácia
Published: January 2023

O presente artigo tem por objetivo apresentar um ensaio genealógico da natureza histórica e discursiva sobre a educação profissional no Brasil, refletindo sobre a construção dos regimes de verdade do currículo do ensino médio integrado ofertado pelos Institutos Federais e as relações de poder estabelecidas nesse processo. As considerações apresentadas dialogam com as teorias pós-críticas do currículo e com o movimento pós-estruturalista ao problematizar algumas condições históricas e discursivas do currículo do ensino médio integrado e observar de que maneira padrões disciplinadores penetram na organização do conhecimento escolar. A argumentação foca no currículo como dispositivo de saber e poder e a ênfase nas repercussões das relações de poder e suas práticas discursivas. Ao dimensionar o tempo, com a marcação histórica do ensino médio integrado, não intencionamos demarcar itinerários históricos, mas os acontecimentos discursivos que se tornam significativos para esse exercício analítico e genealógico.
LIÇÕES DE DARCY: DO MODERNISMO DO SÉCULO XX À PANDEMIA DO SÉCULO XXI
Authors: Duarte Pedro
Published: January 2023

O artigo analisa os motivos que fizeram o pensador indígena Ailton Krenak temer um metafórico segundo exílio de Darcy Ribeiro: se o primeiro foi político, após o Golpe Militar de 1964, o mais recente seria intelectual, pelo esquecimento de sua obra. Formula-se, como hipótese, que dois fatores ajudam a entender a ameaça de exílio do legado de Darcy Ribeiro: o primeiro é a forma de escrita ensaística e imaginativa dos seus livros, que desafia o cientificismo acadêmico; o segundo é o conteúdo modernista de seu projeto de Brasil, fundado na inclusão indígena e na educação, tal como sonhara Oswald de Andrade nos anos 1920 ao falar da dupla base com “a floresta e a escola”, o que desafia a história etnocida e ignorante que governou o país.
Correlation between tax revenues and gross domestic product: Evidence from the developing economy
Authors: Çollaku Lum , Balaj Driton , Hajdini Artan
Published: January 2023

This paper examines the relationship between tax revenues and the economic growth of Kosovo as a developing country. The paper uses quarterly time series data for 2010:Q1–2021:Q4 collected by the Kosovo Statistical Agency and the Ministry of Finance of Kosovo. The data were analyzed using EViews v10. Augmented Dickey-Fuller (ADF), Johansen cointegration test, vector autoregressive (VAR) model, vector error correction model (VECM) estimation, and Granger causality test was used to analyze the model. The VECM results showed that fluctuations in tax revenues have a negative effect on the gross domestic product (GDP) in the long run. Using data from nine countries, Nguyen and Darsono (2022) demonstrated that tax revenues have an adverse effect on economic growth. Using Granger causality, the results showed that tax revenue growth could cause GDP growth, and GDP growth can cause tax revenue. Okonkwo (2018) recommends that the government tighten tax collection methods and regularly evaluate tax policies to maintain the country’s tax revenue. Since taxes boost economic growth and boost taxes in emerging economies, the government should implement effective tax collection measures. The importance of the paper lies in the fact that fluctuations in tax revenues are an important cause of negative changes in GDP in the long run.
Ventajas y Desventajas del teletrabajo en Sudamérica frente a la pandemia covid-19
Authors: Ramírez-Velásquez Joanna Carolina , Vega Abad Cesar Remigio , Villagómez Martha Narcisa
Published: January 2023

El impacto de la pandemia por covid-19 en Sudamérica causó una gran emergencia en los sectores de salud, económico, social, familiar y de manera transcendental en el ámbito laboral, lo que convirtió al teletrabajo en una de las herramientas para atenuar la problemática. En este contexto, la investigación se planteó como objetivo identificar las ventajas y desventajas que ha tenido la implementación de este modo de trabajo en Sudamérica, desde los ámbitos jurídicos, tecnológicos y sociales. La metodología partió de una investigación documental, con alcance exploratorio, descriptiva y no experimental, donde se procedió a examinar las fuentes legislativas que regulan el teletrabajo en Sudamérica; del mismo modo, para los artículos científicos de revistas indexadas nacionales e internacionales que han tratado el tema de estudio, se utilizó la técnica de revisión bibliográfica en las bases de datos científicas. Ante la crisis que provocó el coronavirus, el teletrabajo constituyó una de las alternativas inmediatas para mantener las actividades laborales en muchos sectores económicos, aun cuando cada Estado en particular presentó desafíos o limitaciones para su adecuada implementación, empezando por su régimen jurídico. En Sudamérica fue la herramienta más viable para la prestación de servicios del sector público y privado, en efecto, su regulación jurídica presentó una importante evolución. Este modo de organización laboral todavía se mantiene y se ha fortalecido su implementación debido al avance de las tecnologías de la información y comunicación.
La patente de invención en la Decisión 486 de la Comunidad Andina y su relación con la contratación estatal en Colombia
Authors: Amaya Rodríguez Carlos Fernando
Published: January 2023

El presente artículo se pretende identificar los puntos convergencia entre la propiedad industrial a partir de los derechos conferidos por las patentes de invención y la contratación estatal como actuación administrativa establecida para la gestión de los fines del Estado. Dicha relación se haya en el interés general, entendiendo que la protección de la propiedad industrial no solo debe ser reputada del titular de derechos conferidos en el ámbito de aquella, sino también en beneficio de la sociedad, lo cual se identifica en las diferencias limitaciones al ejercicios del privilegio de patente, siendo esto último una de las finalidades del sistema de compra pública, aspecto que será analizado en el ámbito de la contratación directa, bien sea por la ausencia de pluralidad de proponentes o la celebración de contratos cuyo objeto tenga relación con el desarrollo de ciencia y tecnología.
Agotamiento de los derechos de propiedad intelectual e importaciones paralelas de medicamentos
Authors: Madrid B Luis Ángel
Published: January 2023

Esta investigación examina el agotamiento del derecho en el sector farmacéutico colombiano y la ausencia de importaciones paralelas de productos farmacéuticos en ese país. Tal carencia, no obstante, la adopción del agotamiento internacional del derecho por la Comunidad Andina y la expedición en Colombia del Decreto 1313 de 2010, en el que se fijan requisitos y procedimientos para autorizar importaciones paralelas de medicamentos y dispositivos médicos. Para efectos de análisis comparativo, se estudia, además, la experiencia europea en la materia.
Noticias del excepcionalismo débil
Authors: Castro Juan Cristóbal
Published: January 2023

Hasta ahora, la lectura por parte de muchos escritores e intelectuales críticos del capitalismo sobre la revolución venezolana se ha concentrado en los últimos años del proceso, destacando la figura de Nicolás Maduro. Sin embargo, durante los primeros años del gobierno de Hugo Chávez hubo claros signos de su avance autocrático. El siguiente trabajo se aproxima a algunos de estos elementos para dilucidar la forma de excepcionalismo que hubo, considerando a su vez las líneas intelectuales que apoyaron por un tiempo esta modalidad de toma de poder decisionista.
Habitat connectivity buffers extinction under extreme droughts in experimental metapopulations
Authors: Li Dongbo , Memmott Jane , Clements Chris
Published: January 2023

Connectivity maintains the spatial dynamics of metapopulations by
promoting dispersal between habitat patches, potentially buffering
populations and communities against continued global change. However,
this function is threatened by habitats becoming increasingly
fragmented, and habitat matrices becoming increasingly inhospitable,
potentially reducing the resilience and persistence of populations. Yet,
we lack a clear understanding of how reduced connectivity interacts with
rates of environmental change to destabilise populations. Using
laboratory microcosms containing metapopulations of the Collembola
Folsomia candida, we investigate the impact of habitat
connectivity on metapopulation persistence under a range of simulated
droughts, a key stressor for this species. We manipulated both drought
severity and the number of patches affected by drought across landscapes
connected by either good or poor-quality corridors. We measured the time
of population extinction, the maximum rate of population decline, and
the variability of abundance among patches as criteria to evaluate the
persistence ability of metapopulations. We show that whilst drought
severity and number of drought-affected patches negatively influenced
population persistence, these results were mitigated by increased
habitat connectivity, which increased population persistence time and
decreased both how fast populations declined and the variability in
abundance among patches. Our results suggest that enhancing spatial
connectivity can increase the persistence of metapopulations, increasing
the time available for conservation actions to take effect, and/or for
species to adapt or move in the face of continued stress. Given that
fragmentation increases the isolation of habitats, improving habitat
connectivity by using good quality corridors may provide a useful
strategy to enhance the resistance of spatially structured populations.
A multi-port interconnected magneto-electric dipole antenna array for 5G applications
Authors: Chen Zihao , Zhang Wenxu , Wang Kai-xu
Published: January 2023

This letter reports a 28-GHz multi-port magneto-electric (ME) dipole
array for 5G applications. The proposed antenna array enlarges the
system polarization diversity with the capability of being utilized as a
balanced antenna, a dual-polarized antenna and a circularly polarized
antenna. Co-planar waveguide (CPW) lines are used to connect ME dipole
radiators to achieve a high gain with simple feeding structure. The
proposed antenna array exhibits a -10dB impedance bandwidth of 12.8%
and a maximal peak realized gain of 13.52 dBi as a balanced antenna, and
exhibits a -10dB impedance bandwidth of 28.57%, a 3-dB axial ratio
bandwidth of 16% and a maximal peak realized gain of 12.15 dBi as a
circularly polarized antenna.
Confinement Fluorescence Effect: Polymer Crystalline Structure Visualization by an Aggregation-Induced Emission Luminogen
Authors: Zhou Lan , Zheng Linlin , Yu Xiaoxiao , Gao Mengyue , Xu Chengjian , Ge Yifan , Bai Tianxiang , Wen Jin , Cheng Yanhua , Zhu Meifang
Published: January 2023

Direct visualization of polymer crystalline structure remains
challenging due to the lack of contrast across different microphases of
polymers. Here we address this conundrum using an aggregation-induced
emission luminogen (AIEgen) with confinement fluorescence effect, which
could be used as a “built-in” sensor to label different crystalline
phases. Computational simulations reveal that the confined space induces
the AIEgens to take a more planar conformation, resulting in a
red-shifted emission spectrum. With this property, the information of
various polymer crystalline forms is converted into different
fluorescence colors, which is attributed to the different spatial
dimensions of the polymer amorphous layer between lamellar crystals
where the AIEgens are located. Finally, polymer crystalline phases
distinction, quantitative crystallinity determination, and stereocomplex
crystals visualization are achieved, providing a relationship between
crystalline microstructure and fluorescence signals. This work
demonstrates the potential of AIE fluorescence technology in polymer
science, providing a theoretical and experimental guideline for the
materials processing and optimization of mechanical performance.
Diagnosing, Imaging and Successfully Treating a Debilitating Case of Bing-Neel Syndrome: A Multidisciplinary Feat.
Authors: Kerley Robert , O’Donnell Niamh , Lynott Fiona , Mulcahy Riona , Hennessy Brian
Published: January 2023

Here we present a diagnostically challenging Bing-Neel Syndrome (BNS)
case successfully treated with systemic chemoimmunotherapy and
ibrutinib, with remarkable clinical response. BNS is an extremely rare
direct central nervous system infiltration by malignant
lymphoplasmocytic lymphoma cells in patients with Waldenstroms
macroglobulinaemia.
The second analysis of automated external defibrillators could recognize pulseless ventricular tachycardia, leading to successful shock delivery in a patient with dilated cardiomyopathy: A case report
Authors: Teragawa Yuki , Teragawa Hiroki , Oshita Chikage , Orita Yuichi , Ochi Makoto
Published: January 2023

In a case of dilated cardiomyopathy complicated by pulseless ventricular
tachycardia, a shock was deemed unnecessary after the first analysis of
the automated external defibrillator (AED). Continued high-quality chest
compressions and strong pressure of the AED pad against the chest wall
led to successful defibrillation after the second analysis.
CBWO: Chaotic Beluga Whale Optimizer for Numerical and Engineering Optimization Problems
Authors: Shrikant * , Saxena Sobhit , Kamboj Vikram Kumar
Published: January 2023

Beluga Whale Optimization (BWO) is a recently developed meta-heuristics
search algorithm to provide good balance between the exploration phase
and the exploitation phase in solving benchmark optimization problems.
However, the local search of the basic BWO algorithm has slow
convergence rate due to its poor exploitation capability. We proposed a
hybrid algorithm using a chaotic variant of the present optimization
algorithm in order to enhance its exploitation ability and abbreviated
as CBWO. To appraise the performance of CBWO, it is first verified on 23
standard benchmark functions. A comparative study has been done that
shows the advantage of the proposed algorithm and associated with a
number of existing algorithms. Simulation results were carried out on
eleven classical engineering problems. Pseudo code of CBWO algorithm is
presented in paper. Results come to know that CBWO could be more
effective in optimization with quicker and advanced convergence rate and
accuracy.
Evaluating the effect of building patterns on urban flooding based on a boosted regression tree: a case study of Beijing, China
Authors: Li Zhen , Wang Zhuowei , Wu Leixiang , Huang Wei , Peng Wenqi
Published: January 2023

Rapid urbanization and global climate change are likely to exacerbate
urban flooding intensity, frequency, and uncertainty. Thus, it is
fundamental and crucial to investigate the dominant influencing factors
for the mitigation of urban flooding. However, the influence of building
patterns on urban flooding remains limited. Taking Beijing, a typical
megacity, as a case study area, we quantified the importance of building
patterns and their interaction effect at the subwatershed scale using
the boosted regression tree (BRT) and geographical detector model
(GeoD). The results indicated that (1) the landscape shape index, slope,
green space ratio and waterbody ratio were the most important
influencing factors determining urban flooding, with a total relative
contribution of 67.23%, (2) building metrics had a certain impact on
urban flooding, and the sum of the relative contribution can reach
21.03%, (3) with urban flooding density, the landscape shape index,
slope, and green space ratio exhibited a combination of negative and
positive correlation, and (4) an enhancement effect existed between
building metrics, especially the building congestion degree and building
density. These findings provide quantitative insights that rational
urban morphology planning can improve stormwater management and promote
urban sustainability in megacities.
Safety Assessment of Coronary Arteries During Left Bundle Branch Area Pacing
Authors: Kong Qiling , Chen Huolong , Hua Juan , Xiong Ziyi , Le Shuyun , Liu Jinwei , Chen Qi
Published: January 2023

Objective: This study aimed to investigate the relationship
between the location of implantation of the Left Bundle Branch Area
Pacing (LBBAP) electrode and the coronary artery and to assess the
safety of LBBAP surgery. Methods: Patients who underwent the
LBBAP procedure and coronary angiography (CAG) at the Second Affiliated
Hospital of Nanchang University between January 1, 2019 to October 1,
2020 were included. We read the patient’s LBBAP and CAG imaging data and
used the nine-partition method to measure the vertical distance from the
tip of the pacing electrode to each coronary artery in multiple
projection positions during the ventricular systolic period. Changes in
the ST-T segment in the electrocardiogram, serum troponin and myocardial
enzyme profiles were observed before and after the LBBAP surgery.
Results: Overall, 50 patients were evaluated. The average
vertical distances from the electrode tip to the left anterior
descending branch (LAD), right posterior coronal descending branch (PD),
left posterior ventricular branch (PL) were 19.69±8.72 mm, 26.09±8.02
mm, and 21.11±7.86 mm, respectively. The minimum were 5.28 mm, 9.51 mm
and 8.69 mm, respectively. CAG in all patients showed no significant
injury to the ventricular septal branch. And there were no elevated
serum troponin or cardiac enzyme profiles. Conclusions: This
study suggested that the coronary arteries were safest when the LBBAP
electrodes were placed within a rectangle formed by the PM, M, PI, and
MI center points. The PM was the ideal position to implant the LBBAP
electrodes, which had a low risk of coronary vascular injury.
COEVOLUTION WITH SPATIALLY STRUCTURED RICE LANDRACES MAINTAINS MULTIPLE GENERALIST LINEAGES IN THE RICE BLAST PATHOGEN
Authors: Ali Sajid , Gladieux Pierre , Ravel Sébastien , Adreit Henri , Meunier Isabelle , Milazzo Joëlle , Cros-Arteil Sandrine , Bonnot Francois , Jin Baihui , Dumartinet Thomas , Charriat Florian , Lassagne Alexandre , He Hiahong , Tharreau Didier , Huang Huichuan , Morel Jean-Benoit , Fournier Elisabeth
Published: January 2023

Traditional agrosystems, where humans, crops and microbes have coevolved
over long periods, can serve as models to understand the
eco-evolutionary determinants of disease dynamics and help the
engineering of durably resistant agrosystems. Here, we investigated the
genetic and phenotypic relationship between rice (Oryza sativa)
landraces and their rice blast pathogen (Pyricularia oryzae) in the
traditional Yuanyang terraces of flooded rice paddies in China, where
rice landraces have been grown and bred over centuries without
significant disease outbreaks. Analyses of genetic subdivision revealed
that indica rice plants clustered according to landrace names. Three new
diverse lineages of rice blast specific to the Yuanyang terraces
coexisted with lineages previously detected at the worldwide scale.
Population subdivision in the pathogen population did not mirror pattern
of population subdivision in the host. Measuring the pathogenicity of
rice blast isolates on landraces revealed generalist life histories. Our
results suggest that the implementation of disease control strategies
based on the emergence or maintenance of a generalist lifestyle in
pathogens may sustainably reduce the burden of disease in crops.
Flash pulmonary edema in the cardiac catheterization laboratory: A case report
Authors: Mehrpooya Maryam , Eftekhari Mohammad Reza , Moghaddasfar Tara
Published: January 2023

We report a 51-year-old female with a history of a degenerated aortic
bioprosthesis and severe valvular dysfunction who was admitted for redo
valve surgery and unexpectedly developed acute flash pulmonary edema, a
dramatic form of cardiogenic pulmonary edema before coronary angiography
and was managed by timely and proper treatment.