bluuebunny/crossref_metadata_2025 huggingface dataset:
Correlation Strength Assessment of Animal Husbandry Components to the Implementation of ASEAN Good Animal Husbandry Practices: A case study in layer farming
Authors: Pribadi Eko Sugeng , Hanun Hanifa , Haryanto Agung Puji , Sutarman Deddy Cahyadi , Utami Sinta Sri , Harahap Rahmat Hidayat , Safika Safika , Kompudu Alfred John Morris , Schoonman Luuk , Utomo Gunawan Budi , Attabany Afton , Rasa Fadjar Sumping Tjatur , Isriyanthi Ni Made Ria
Published: May 2023

ASEAN Good Animal Health Practice (GAHP)is a joint product of ASEAN member countries to be applied in layingfarms. The Researchaimed to explore management practices of laying farms in accordance withthe guidelines from ASEAN GAHP. South Lampung District and East Lampung District were the chosen locations in thisResearch. The ASEAN GAHP-based questionnaires were arranged and used for thisResearch. A variety of data analysis were conducted namely normality analysis, validity analysis, reliability analysis, descriptive analysis, and correlation analysistechnique.TheResult showed there were no significant difference were found between South Lampung District and East Lampung District farmers in the implementation of GAHP components in layer farms. Application of Veterinary Control Number(Nomor Kontrol Veteriner,NKV)issued by Government becomes a strong driver for farmers to implement the ASEAN GAHP. The Research concluded the components which havea strong relationship in the implementation of ASEAN-GAHPwere waste management, personnel hygiene, transportation, water quality and treatment, and surveillance and diseases control.
The Effects of Using Clove Meal (Syzygium aromaticum L.) as Feed Additive on Nutrient Digestibility and Metabolizable Energy of Broiler Chicken
Authors: Djunaidi Irfan H. , Azizah Siti , Shakal Mohamed
Published: May 2023

This study was aimed at determining the effect of clove meal addition in diets on nutrient digestibility and metabolizable energy in broilers and whether it could be an alternative to antibiotics or not. In this experiment, twenty-four 35-day-old broilers of the chicken strain Lohman were used. A total of twenty broiler chickens were selected as representatives for determining the digestibility. The treatment diets were: T0 (basal diet), T1 (basal diet + 0.25% clove meal), T2 (basal diet + 0.5% clove meal), T3 (basal diet + 0.75% clove meal), and T4 (basal diet + 1% clove meal). The variables measured were dry matter digestibility, organic matter digestibility, apparent protein digestibility, true digestible protein (TDP),Apparent Metabolizable Energy (AME), True Metabolizable Energy (TME), Nitrogen Corrected Apparent Metabolizable Energy (AMEn) and Nitrogen Corrected True Metabolizable Energy (TMEn). A completely random design was used, with five treatments and four replications. The data were analyzed using analysis of variance (ANOVA), and differences among treatments were examined using Duncan’s multiple range test. The results show that the treatment influences significantly (P<0.05) of dry matter, organic matter, apparent protein digestibility, and TDP. In contrast, there wereno significant effects (p>0,05) of dietary treatment on AME, TME, AMEn, and TMEn. However, the addition of 0.75% clove meal indicated the best result in AME, TME, AMEn, and TMEn. It can be concluded that the experiment indicated that the addition of clovemeal (Syzygium aromaticum L.) in 0.75% on the diet of broiler chickens was effective in increasing the digestibility of dry matter, organic matter,crude protein, TDP, and metabolizable energy.
Characterization and Production of Goat Milk Kefir-Peptide on Triglyceride Synthesis of Cell Model of 3T3-L1
Authors: Hati Dian Laksamana , Andarini Sri , Handayani Dian , Rosyidi Djalal , Radiati Lilik Eka
Published: May 2023

Goat milk kefir (GMK) refers to fermented products, generated through fermenting milk with microbial culture called kefir grains. Prior studies have reported the changes in kefir quality properties during aging process in which fermentation continues, resulting in changes of the peptide content. This research aims to investigate the effect of aging time on GMK–peptide characteristics to inhibite triglyceride syntheses on cells model of 3T3-L1. In this study, GMK were stored at 4 ± 1 oC for 0, 2, 4, 6 and 8 weeks, respectively. The protein profile was characterizedby implementing SDS-PAGE. The result of experiment indicated no protein degradation during the 6 weeks of aging period particularly for high molecular weight at 84 kDa, 80 kDa and 65 kDa. The GMK-supernatant from 8 weeks storage was performed by applying ultrafiltration membrane cut off < 30 kDa (UFC8 030.08). GMK-filtrate fractions (GMK-peptide) was collected as peptides. After 8 weeks of aging period, kefir protein profile was found to consist of peptide fractions and amino acid. The proteolytic activity of kefir grain increased linearly along with aging time (0-8 weeks). During aging period, the proteolytic activity of grain kefir released peptides and amino acid. In particular, the antioxidant activities were found significantly different (p<0.05) during aging periods. The antioxidant activities of GMK-peptide increased along with the elevating peptide concentration, from 3.30 % to 55.73%, with derivate by GMK-peptides of 2.75 – 10.39 mg/ml. Obesity associated with adipocyte hypertrophy occurred when TG accumulation.GMK-peptide of 100 mg/ml indicated the lowest TG level (2.00 ± 0.03 mg/dl). This finding was in line with the inhibition of TG synthesis (61.14 ± 3.26 %). However, GMK-peptide contained antioxidant potency due to may be corelated with decreasing TG synthesis.The study thus suggested the important role of kefir to prolong aging in generating higher peptide bioactive as antioxidant and inhibition of TG synthesis of cell model of 3T3-L1
The Effect of The Addition of Skim Milk Powder to Broiler Liver Nuggets on Physicochemical and Organoleptic Quality
Authors: Amertaningtyas Dedes , Evanuarini Herly , Mutia Sabitha Hikmah , Zahra Lulu Luthfiah
Published: May 2023

Chicken nuggets are a popular product among the public, but because of the relatively high price, not all people can consume them. The development of innovation in processed nugget products is increasingly diverse, such as using chicken liver added skim milk powder to improve nutritional quality, physical quality, and consumer preferences. The purpose of this research was to determine the effect of the addition of skim milk powder on broiler liver nuggets in terms of moisture content, water activity (Aw), and physical quality. The research method was a laboratory experiment with a completely randomized design (CRD) is P0 (0%), P1 (5%), P2 (7%), and P3 (10%) for differences adding skim milk powder and the data were analyzed using analysis of variance or ANOVA. The results showed that the addition of skim milk powder was not significantly different (P>0.05) on moisture content, water activity (Aw), texture, and physical quality of yield and color (L*, a*, b*), but had an effect on significantly (P<0.05) in organoleptic (color, taste, and odor) and some of the essential amino acids. The conclusion was that the addition of skim milk powder on 10% was used as a treatment best with moister content, water activity (Aw), and texture, than for physical quality, the best addition was 10% for yield, color, tasteMand color L* (brightness), a* (redness) b* (yellowness). As a reference for further research can compare other commodity types of the liver.
Synergy of Combining Methionine Restriction and Chemotherapy: The Disruptive Next Generation of Cancer Treatment
Authors: KUBOTA YUTARO , HAN QINGHONG , AOKI YUSUKE , MASAKI NORIYUKI , OBARA KOYA , HAMADA KAZUYUKI , HOZUMI CHIHIRO , WONG ANDREW C.W. , BOUVET MICHAEL , TSUNODA TAKUYA , HOFFMAN ROBERT M.
Published: May 2023

All cancer cell types are methionine-addicted, which is termed the Hoffman effect. Cancer cells, unlike normal cells, cannot survive without large amount of methionine. In general, when methionine is depleted, both normal cells and cancer cells synthesize methionine from homocysteine, but cancer cells consume large amounts of methionine and they cannot survive without exogenous methionine. For this reason, methionine restriction has been shown to be effective against many cancers in vitro and in vivo. Methionine restriction arrests cancer cells in the S/G2-phase of the cell cycle. Cytotoxic agents that act in the S/G2-phase are highly effective when used in combination with methionine restriction due to the cancer cells being trapped in S/G2-phase, unlike normal cells which arrest in G1/G0-phase. Combining methionine restriction and chemotherapeutic drugs for cancer treatment is termed the Hoffman protocol. The efficacy of many cytotoxic agents and molecular-targeted drugs in combination with methionine restriction has been demonstrated. The most effective method of methionine restriction is the administration of recombinant methioninase (rMETase), which degrades methionine. The efficacy of rMETase has been reported in mice and human patients by oral administration. The present review describes studies on anticancer drugs that showed synergistic efficacy in combination with methionine restriction, including rMETase administration. It is proposed that the next disruptive generation of cancer chemotherapy should employ current therapy in combination with methionine restriction for all cancer types.
Long-term Progression-free Survival With Pemetrexed Plus Bevacizumab in NSCLC Patients
Authors: HAYASHI SHIGEN , MIYAZAKI KUNIHIKO , SHIOZAWA TOSHIHIRO , OKAUCHI SHINICHIRO , SAKURAI HIROFUMI , AKIYAMA TATSUYA , NOMURA AKIHIRO , SATOH HIROAKI , HIZAWA NOBUYUKI
Published: May 2023

Background/Aim: Pemetrexed (PEM) and bevacizumab (BEV) are commonly used in combination as second or subsequent line regimens and maintenance therapy after platinum + PEM + BEV therapy for advanced non-small cell lung cancer (NSCLC). Median progression-free survival (PFS) for PEM + BEV has been reported to be less than six months in both clinical trials and clinical practice, but in clinical practice, we found that some patients demonstrate long-term PFS. Furthermore, there is a paucity of clinical practice data on whether long-term administration of PEM + BEV causes renal dysfunction. This study aimed to clarify these aspects in clinical practice. Patients and Methods: A retrospective review of patients with advanced NSCLC treated with PEM + BEV between September 2011 and June 2022 at four hospitals was conducted. Long-term PFS in PEM + BEV therapy was defined as ≥12 months. Results: During the study period, 109 patients received PEM + BEV treatment. Of them, 42 (38.5%) achieved long-term PFS ≥12 months. No significant differences in patient characteristics were found between patients with PFS ≥12 months and <12 months, except for ‘relapse after resection’. Univariate and multivariate analysis showed that the favorable factor for PFS was ‘relapse after resection’. With regard to influence on renal function of PEM + BEV therapy, no significant difference was found before and after PEM+BEV therapy between these two groups. Conclusion: NSCLC patients commonly achieved long-term PFS with PEM + BEV therapy with no observed effects on renal function.
Successful Phytotherapy for Acute Refractory Radiation Cystitis in a Cervical Cancer Patient: A Case Report
Authors: HOANG BA X. , HAN BO , TRAN HUNG Q. , FANG WILLIAM H. , TRAN HAU D.
Published: May 2023

Background/Aim: Radiation cystitis is a frequent complication that can occur after therapeutic irradiation of pelvic cancers. The current treatment for this condition is complex and often ineffective. Case Report: We present a clinical case of a 54-year-old patient diagnosed with small cell cervical cancer FIGO stage IIIC who developed grade 2-3 radiation cystitis following post-operational chemoradiation therapy. The patient exhibited increased urinary urgency and frequency, dysuria, and low abdominal pain, which failed to respond to acupuncture and corticosteroid treatments. A course of Ich Nieu Khang phytotherapy tablets, resulted in significant improvement of symptoms within 24 hours of initiation. The symptoms resolved completely within 10 days, and ultrasonography documented a marked decrease in bladder wall thickening and improved bladder evacuation function. The phytotherapy was well-tolerated, and no side-effects were observed during the 60-day treatment period. Conclusion: These findings suggest that phytotherapy may be viable for managing radiation cystitis. However, further controlled clinical trials are needed to confirm the efficacy of Ich Nieu Khang and promote its broader clinical applications.
Bioproduction of Chitin Hydrolysate Containing N-Acetylglucosamine by Serratia marcescens PT6 Crude Chitinase and Its Effects on Bacterial Growth Inhibition in Various Temperature
Authors: Puspita Indun Dewi , Ratnawati Susana Endah , Setiawan Hendri , Murwantoko Murwantoko , Ustadi Ustadi , Ratkowsky David , Tamplin Mark
Published: May 2023

N-acetylglucosamine (GlcNAc), a chitin monomer, can be used as a natural preservative to ensure food quality and safety. Combining natural preservatives with low storage temperature offers physical hurdles to bacterial growth in food. This study aimed to produce chitin hydrolysate containing GlcNAc using Serratia marcescens PT6 crude chitinase and investigate its effect on bacterial growth rate as a function of temperature. Crude chitinase from partial purification was used to hydrolyze 1.3% colloidal chitin. The optimal enzymatic conditions were pH 6 and 45˚C for 120 min, at an enzyme:substrate ratio of 1:1, yielding a 65.6 µg/mL GlcNAc. Inhibitory activity of hydrolysate containing 2.5-7.5 ppm GlcNAc on Escherichia coli, Staphylococcus aureus, Bacillus cereus, and Vibrio parahaemolyticus was measured at 4, 15, and 30oC in nutrient broth. Bacterial growth was measured using of optical density for each combination of GlcNAc concentration and temperature. Growth curves fitted by the Baranyi and Roberts model were developed using DMFit software. The growth rate was converted to the square root and then modeled as a function of temperature using the Ratkowsky square root model. Incubation temperature exerted a pronounced effect on the inhibition of all bacterial species (P<0.0001), with the greatest effect observed for E. coli at 30°C (P<0.0001), and the least effect for V. parahaemolyticus (P=0.0878). The inhibitory effect of GlcNAc in chitin hydrolysate was only significant for E. coli (P<0.0001) and S. aureus (P=0.0041). This study revealed that the effect of temperature in growth inhibition was more significant than GlcNAc addition. However, a reduction in bacterial growth with the addition of GlcNAc at 30°C was observed, which may be effective for food encountered thermal abuse conditions. Further investigation of the effect of GlcNAc on bacteria structure and metabolism is required to elucidate the mechanism of GlcNAc as a food preservative.
Heat Exchanger Network (HEN) Analysis of The Power Plant Industry Using Aspen Energy Analyzer Software
Authors: Muharja Maktum , Widjaja Arief , Darmayanti Rizki Fitria , Airlangga Bramantyo , Anugraha Rendra Panca , Fauziyah Mar'atul , Wijanarto Eko , Sholehuddin Mohammad , Khamil Achri Isnan
Published: May 2023

Heat recovery is considered as the key to improve energy efficiency in the process design. An appropriate heat exchanger network (HEN) design is an effective tool to maximize heat recovery from the process streams and to minimize energy consumption. The objectives of this study were arranging optimum HEN based on the annual cost in the power industry. HEN in the Paiton Steam Power Plant, East Java, Indonesia, was designed using spreadsheet and Aspen Energy Analyzer with Peng-Robinson equation. Pinch analysis was conducted by comparing Tmin (10°C - 19°C) to obtain Maximum Energy Recovery (MER) and Heat Exchanger Area (HEA). The HEN design was optimized using grid diagram. Simulation in this study succeeded to reduce the annual cost the most effectively at ∆Tmin 16°C. This design optimized the process integration and contributed to the capital, operation, and total annual cost reduction of 14.3%. The maximum energy recovery was 286,706 kW and HEA 138.790 m2. This result is a solution for Steam Power Plant as an effort for enhancing energy efficiency and the company competitiveness.
Supervised Machine Learning and Multiple Regression Approach to Predict Successfulness of Matrix Acidizing in Hydraulic Fractured Sandstone Formation
Authors: Kurniawan Candra , Azis Muhammad Mufti , Ariyanto Teguh
Published: May 2023

The success rate of matrix acidizing in hydraulic fractured sandstone formation is less than 55%, much lower compared to the more than 91% success rate in carbonate formation. The need for alternative approaches to help the success ratio in matrix acidizing is crucial. This paper demonstrates a modeling technique to improve the success ratio of matrix acidizing in a hydraulic fractured sandstone formation. Supervised machine learning with 4 models of a neural network, logistic regression, tree, and random forest was selected to predict the successfulness of matrix acidizing in hydraulic fracturing. In parallel, multivariate analysis of principal component regression and partial least square regression approach were utilized to predict the oil gain of the job. For qualitative prediction, the results showed that the random forest was the best model to predict the successfulness of the job with the area under the curve (AUC) of 0.68 and precision of 0.73 in the training model with 70% of the data. Subsequently, the validation test with the rest of the data (30% data) gave 0.51 AUC and 61% precision. For quantitative prediction, the net oil gain was evaluated by using principal component regression (PCR) and partial least square regression (PLS-R). The PCR and PLS-R model gave a coefficient of determination (Rsquare) of 0.22 and 0.35, respectively. The p-value of PLS-R was 0.047 (95% confidence interval) which indicates that the model is significant. The results of this work demonstrate the potential application of supervised machine learning, principal component regression, and partial least square regression to improve candidate selection of oil wells for matrix acidizing especially in hydraulic fractured wells with limited design data.
Spent Coffee Grounds Biochar Composite Phase Change Material Design Challenges in a Lab-Scale Solar Water Heater System for Thermal Energy Storage
Authors: Mondragon Raphael Angelo , Boonyubol Sasipa , Cheng Shuo , Cross Jeffrey Scott
Published: May 2023

Thermal energy storage systems that use composite phase change materials (CPCM), such as paraffin wax and nonbiodegradable high-density polyethylene, are gaining attention in recent years due to the effort to resolve energy issues. There is a need to undertake research and development on how to prepare durable CPCMs from thermo-chemically treated biowastes, a renewable resource. Raw spent coffee grounds (SCG) have been experimented on previously, but more research needs to be conducted on CPCMs prepared from pyrolyzed SCG-biochar (SCGB) for use in a water tank. This research investigated a biodegradable CPCM made from SCGB and carnauba wax in a lab-scale solar water heater system. The carnauba wax loading of 60% was chosen due to the minimized thermal wax leakage from the PCM. Thermal characterization results revealed that the latent heat of SCGB CPCM is 88.47 J/g which was found to be competitive compared to other biodegradable CPCMs reported earlier. The results also show further potential for using SCGB and carnauba wax as a CPCM in a thermal energy storage system.
Thermal and Physical Properties of Hybrid Composites Made from Used PET Bottles and Date Palm Fibers Filled with Unsaturated Polyester
Authors: Habila Tahir , Meftah Yazid , Maou Samira
Published: May 2023

Recycling polyethylene terephthalate (r-PET) bottles is a sustainable solution for reducing the accumulation of r-PET in landfills. The primary goal of this study is to determine the viability of combining fibers derived from waste r-PET bottles (r-PET) and date palm fibers (DPF) to produce hybrid unsaturated polyester (UP)-based composites. Hand lay-up was used to make the UP/r-PET/DPF composites, which had 10%, 20%, and 30% r-PET and date palm fibers by weight, with equal weights of the two. Recycled r-PET bottles and date palm leaflets were cut into 5–10 mm lengths and incorporated into the UP matrix. The composites were characterized by their flexural, morphological, thermal, dynamical mechanical, and water absorption characteristics. The thermal behavior of the composites improved when r-PET and DPF were added at high temperatures. However, the composites' flexural strength and storage modulus decreased due to their non-uniform distribution, which made it hard for the fillers to adhere to the UP matrix. SEM micrographs of the composite's fracture surfaces showed that the amount of agglomeration eventually increased as the filler loading increased. Lastly, the composites showed significant resistance to water absorption with lower proportions of DPF and r-PET fibers.
Pengantar Redaksi
Authors: Pemuda Jurnal Studi
Published: May 2023

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Bagaimana Hidup Saya Setelah Ini? Aspirasi Masa Depan Narapidana Ditinjau dari Perspektif Kepemudaan
Authors: Machdi Regisda
Published: May 2023

Penelitian ini bertujuan untuk mengeksplorasi aspirasi masa depan narapidana ditinjau dari perspektif kepemudaan. Narapidana yang berada di usia produktif, sebagaimana pemuda lainnya, dituntut untuk sukses dalam tiga domain kehidupan: pendidikan, pekerjaan, dan pernikahan. Adanya beberapa masa dalam kehidupan mereka yang harus dikungkung dalam sebuah Lembaga Pemasyarakatan (Lapas) ditambah beban akan stigma negatif setelah keluar dari Lapas membuat tiga domain tersebut tidak bisa melaju bersamaan. Pendidikan menjadi domain kehidupan yang harus ditinggalkan demi mengejar kesuksesan di domain yang lain. Optimisme akan masa depan muncul ketika ada kepastian lapangan pekerjaan dan rumah bagi mereka untuk kembali pulang.Kata kunci: narapidana, aspirasi masa depan, pemuda
Motivasi, Pengalaman, dan Harapan Kaum Muda Bali Bekerja di Kapal Pesiar
Authors: Nilan Pam , Artini Luh Putu
Published: May 2023

Artikel ini menjelaskan fenomena bekerja di kapal pesiar di kalangan kaum muda di Indonesia, khususnya Bali. Subjek penelitian adalah 35 orang yang terbagi menjadi 3 kelompok yaitu: calon pekerja, pekerja, dan pensiunan pekerja kapal pesiar untuk men dapat gambaran yang lengkap tentang motivasi, pengalaman dan harapan generasi muda Bali bekerja di kapal pesiar. Data menunjukkan bahwa calon pekerja memiliki motivasi tinggi untuk bekerja di kapal pesiar untuk memperbaiki ekonomi keluarga dan menggapai masa depan yang cerah. Kelompok pekerja menggambarkan beratnya bekerja di kapal pesiar yang tidak sejalan dengan apa yang dibayangkan oleh calon pekerja. Sementara pensiunan yang telah memiliki modal usaha dari bekerja selama 10-12 tahun di kapal pesiar mempunyai harapan untuk memulai sebuah usaha yang memiliki prospek yang bagus. Namun dengan kurangnya pengetahuan kewirausahaan dan ketrampilan mengelola usaha, mereka memiliki keragu-raguan dan bahkan harus mengalami kegagalan. Pe nelitian ini bisa dijadikan acuan bagi instansi  terkait di Indonesia untuk mendesain bentuk pelatihan kewirausahaan yang bisa membangun investasi modal manusia dan dapat menjadi terobosan pemerataan ekonomi di kabupaten-kabupaten yang memiliki tingkat kesejahtraan kurang.Kata kunci: pekerja kapal pesiar, pelatihan kewirausahaan, pemerataan ekonomi
Ben Urip Tetep Semeleh Dinamika Pemuda Kelompok Banyumili Dusun Gadingsari Desa Mangunsari Kecamatan Sawangan Kabupaten Magelang
Authors: Larasati Ciptaningrat
Published: May 2023

Artikel ini berupaya untuk mengulas keseharian hidup pemuda kelompok Banyumili yang berada di dusun Gadingsari, desa Mangunsari Kecamatan Sawangan Kabupaten Magelang. Secara turun menurun, sebagian besar masyarakat dusun Gadingsari menggantungkan hidup dari sektor pertanian. Kondisi alam dusun Gadingsari yang subur menjadikan wilayah ini menjadi salah satu basis pengembangan sektor pertanian di Kabupaten Magelang. Sebagaian besar wilayah dusun Gadingsari merupakan lahan pertanian produktif. Di sisi lain, kondisi ini tak lantas membuat masyarakat dusun Gadingsari lepas dari himpitan ekonomi. Sebagian besar masyarakat dusun Gadingsari hidup dibawah garis kemiskinan. Hampir 90% petani di dusun Gadingsari merupakan petani penggarap. Sejauh ini lahan produktif hanya dapat diakses dan dimiliki oleh sebagian masyarakat saja. Persoalan lain terkait pengelolaan sektor pertanian adalah intervensi modal investor hortikultura dariKorea Selatan yang membuat kondisi sosial ekonomi petani penggarap semakin terpuruk. Kondisi ini berimplikasi pada tingginya arus urbanisasi yang dilakukan masyarakat dusunGadingsari. Ditengah tingginya arus urbanisasi, pemuda melalui kelompok Banyumili hadir membangun sumber ekonomi alternatif di desa dengan mengembangkan budaya ikan lele menggunakan terpal. Sejak berdiri pada tahun 2010 , tercatat 16 orang pemuda sudah menjadi anggota kelompok ini. Selain diyakini strategi alternatif pengelolaan lahan tidak produktif seperti pekarangan rumah, budidaya ikan lele menggunakan sistem ini diharapkan mampu meningkatkan kesejahteraan ekonomi masyarakat dusun Gadingsari.Kata kunci : kelompok Banyumili, pemuda, pengelolaan lahan, budidaya lele
Interconnectedness and the Value of Life: A Deep Ecological Analysis of 'Do Androids Dream of Electric Sheep?' by Philip K. Dick
Authors: Shekakomi Samira Mehdipour
Published: May 2023

This article examines the ecological themes present in Philip K. Dick's "Do Androids Dream of Electric Sheep?" through the lens of Warwick Fox's deep ecology theory. The novel emphasizes the interconnectedness of all life, demonstrating the importance of recognizing our place within a larger ecological system. The absence of non-human life is portrayed as a contributing factor to the degradation of the environment, emphasizing the intrinsic value of non-human life in ecological systems. The consequences of anthropocentrism, including environmental destruction and a lack of empathy for non-human beings, are explored. The relationship between technology and ecology is also examined, with the potential for both degradation and restoration. Overall, the article suggests that recognizing the interconnectedness of all life and valuing non-human life are essential for the health and survival of the entire ecosystem.
Innovative-LAB
Authors: More Manasi
Published: May 2023

Abstract: The concept of Internet of Things (IoT) requires the seamless connectivity of millions of heterogeneous devices. In today’s World, implementation of IoT based smart Lab has drawn a huge attraction and become a prominent area of research. This research work presents an approach for smart Lab automation using IoT that can be controlled wirelessly. Lab automation system means monitoring and controlling of Lab appliances remotely using the concept of internet of things (IOT). In this method we use mobiles or computers to control the basic Lab appliance and make it function through the designed web page with internet connection/local area network (LAN) servers. This type of Lab is also known as smart Lab. The concept of applying automation in the sectors of housing is selling like hot cake. Western countries have welcomed the concept of automation into their Labs with open arms. Our country is keeping up with the pace of modernization too. Different approaches to automating Labs have been implemented. The best among this is Lab automation system using IOT. IOT provides the feasibility of operating the Lab automation system from anywhere around the world using internet. It reduces use of excessive or unnecessary human efforts and improves the standard of living of the people in our society.
A Review on Novel and Comprehensive Analysis of Shear Bending and Torsion in Symmetrical and Unsymmetrical Multistory Building
Authors: Suryawanshi Jagmohan , Grover Prof. Rakesh Kumar
Published: May 2023

Abstract: A structure can be classified as irregular if it contains irregular distributions of mass, stiffness and strength or due to irregular geometrical configurations. The behavior of any building depends on the arrangement of structural elements present in it. The important aspects on which the structural configuration depends are geometry, shape and size of the building. In reality, many existing buildings contain irregularity due to functional and aesthetic requirements .However, past earthquake records show the poor seismic performance of these structures. This proposal will try to ignorance of the irregularity aspect in formulating the seismic design methodologies by the seismic codes.
ChatGPT: Revolutionizing Education Administration-A Case Study Analysis
Authors: Pawar Mr. Sumit Dattatrey
Published: May 2023

Abstract: The advent of Artificial Intelligence (AI) has brought significant advancements in various fields, and the education sector is no exception. Chatbots, specifically those powered by Generative Pre-trained Transformer 3 (GPT-3) technologies, have revolutionized educational administration in recent years. This paper presents a case study analysis along with benefits and limitations of ChatGPT in educational administration. The case study analysis focuses on the implementation of ChatGPT in educational institutions for administrative work. The study highlights the advantages of using ChatGPT, such as improving accessibility, efficiency, and accuracy in administrative tasks, enhancing staff engagement and performance, and reducing the workload of administrative staff. The findings of this study can inform future research and provide insights for educational institutions planning to adopt ChatGPT in their administrative processes.
Critical Analysis of Shukra Dhatu in Male and Female W.S.R to Post-Menopausal Osteoporosis in Females
Authors: Meend Dr. Sonia , Yadav Dr. Sunil Kumar
Published: May 2023

Abstract: Kshaya means “Swapramana Hani” i.e decrease in the quantity of the respective substance.1 Chakrapani dutta explains it as “Nyunatva” which means very less in amount. Acharya Vijayrakshita in Madhukosha Teeka has given detailed description about Pratiloma Dhatu Kshaya and also mentioned Swabhaava as one of the reasons for the Shukra Kshaya. When Shukra Kshaya occurs in a person, then Pratiloma Gati (movement) of Vayu occurs, due to which the first affected Dhatu is the Majja Dhatu. Shukra term denotes for both male and female Shukra, and not only male Shukra. Artava of female should also be considered here. Two forms of Shukra can be seen in the body. One is Dhatu Roopa, and other is the Beeja Roopa which are present in both male and female. The Beeja form of Shukra also has two components i.e Sthira Bhaga (Static) and Chala Bhaga (Dynamic) part. When Kshaya of Shukra is observed, both the forms i.e Dhatu and Beeja forms should be taken into consideration. This Kshaya of Shukra Dhatu again leads to Shosha of the Sneha Bhaga of body and leads to Pratiloma Gati of Vayu. This leads to the retrograde Kshaya of Dhatu. Due to this, Majja Dhatu gets affected first. This Majja Dhatu Kshaya has drastic effects on the Asthi Dhatu and leads to retrograde Kshaya, symptoms like Asthi Saushirya, Asthi Laghuta, Asthi Daurbalya etc. are markedly seen. These symptoms show striking similarity with the features of Osteoporosis.
Prediction of Coefficient of Discharge for Oblique Sharp Crested Weir using ANN Model
Authors: Umale Vidhi
Published: May 2023

Abstract: The application of artificial neural networks for solving complex civil engineering problems is of huge importance. This paper presents some of the positive aspects of the neural network’s model that are used for the determination of the coefficient of discharge of oblique sharp crested weir. Sharp crested weirs are used to measure flow rate and control upstream water surface in irrigation canals and laboratory flumes. The main advantages of such weirs are ease of construction and capability of measuring a wide range of flows with sufficient accuracy. ANN models have been developed to predict the discharge coefficients of oblique sharp-crested weirs for free flow cases using Borgheiet al.’s experimental data.
Automatic GSM Arduino based Energy Meter Reading
Authors: Rao Dr. A Hanumantha , Kumar K Santosh , G Sharana Basava , Niveditha K , Shri K Divya
Published: May 2023

Abstract: The main objective of the project is to develop a GSM Aurdino based energy meter reading system and load control through GSM. Electricity department sends employees to take meter reading every month, which is an expensive and time consuming job. The proposed project provides a convenient and efficient method to avoid this problem. The electricity department and the user can get the readings of the energy meter of consumers via SMS. The loads can also be controlled by the user of this system via GSM using this project. A Controller input is effectively in GSM Based to a digital energy meter that takes the reading from the energy meter and displays the same on an cell phone display. The reading of the aurdino based energy meter is also sent to the control room by GSM. This GSM can also receive commands from the Software to control the owners electrical loads. On receiving command it can switch ON/OFF the loads.
Solar Charging Station for LEV: A Design and Feasibility Study
Authors: Shri K. Karly , Vennila C.
Published: May 2023

Abstract: As the need for sophisticated transportation system rises due to economic development and cultural comfort, global warming and some dangerous climate changes are becoming more frequent. Every government is promoting the use of electric vehicles to combat the problem of global warming caused by the transportation.(EVs), As the number of electric vehicles on the road increases, charging EVs using infrastructure based on fossil fuel is neither efficient nor cost effective. As a result, an electric vehicle charging station that uses renewable energy has tremendous potential and control. In the present situation, a battery energy storage system and a solar powered electric vehicle charging station are necessary. For effective power management in the charging station between solar, BESS, grid and EVs, an efficient charging station design with Incremental conductance (INC) voltage controlled MPPT, PI controller, grid with inverter is design and evaluated in MATLAB/Simulink. Additional grid assistance is advised to ensure that the charging station has uninterrupted power without adding to the load on the grid.
Detection of Fake Currency using Machine Learning
Authors: R N Pushpa
Published: May 2023

Abstract: The problem of detecting fake currency notes is crucial for maintaining the integrity of the economy. In recent years, there has been a surge in the use of deep learning models for detecting counterfeit currency using image processing. For Human being it is very difficult to identify fake currencies, So automatic systems for detection of fake currency is important. In this project, we propose a Convolutional Neural Network (CNN) model for detecting fake currency notes. To train our model, we use a dataset of images containing both genuine and fake currency notes of different denominations. The dataset is preprocessed by resizing all images to a fixed size and normalizing the pixel values. The pre-processed images are then split into training and validation sets for training and testing the model, respectively. This project is modelled as a CNN for automatic feature extraction and classification. The Experimental results validate that the proposed model effectively recognises a real and counterfeit currencies of various denominations with the confidence score.
South-West and North-East Monsoon Precipitations Bright Band Characteristics over Kadapa, Semi-arid Regions of India
Authors: Rohini B. , Bharghavi K. , Rajesh P. , Bharathi P. Lakshmi , Sushmitha H.
Published: May 2023

bstract: Long-term (3-yrs) observation of precipitation during Southwest (SW) and Northeast (NE) With and without Bright Band/melting layer using a Micro Rain Radar (MRR) is investigated. Profiles of DSD in Bright Band (BB) and Non-Bright Band (NBB) cases demonstrate that the BB rain events are associated with higher number concentration of larger drops and NBB events are associated with higher concentration of smaller drops.
C.N.S. Protective Drugs: An Overview
Authors: Tambakhe Jagruti , Singh Varinder , Parwe Shweta , Nisargandha Milind , Asutkar Sheetal
Published: May 2023

Although regulatory authorities presently authorize extremely few drugs for dealing with multifactorial conditions and conditions of cognition such as Alzheimer's, specific plant-derived agents, consisting of, for instance, galantamine and rivastigmine (a semi-synthetic derivative of physostigmine) finding an application in contemporary medicine. However, in Ayurveda, the Indian traditional system of medicine which is more than 5000 years of ages, selected plants have long been categorized as 'Medhyarasayanas,' from the Sanskrit words 'Medhya,' indicating intellect or cognition, and 'Rasayana,' implying 'rejuvenation.' These plants are utilized both in natural and traditional medicine and offer advantages that pharmaceutical drugs do not have. The article is an attempt to examine the most critical medical plants, consisting of Vacha (Acorus calamus), Ashwagandha (Withania somnifera), Vidhara (Argyreia Nervosa), Shankhapushpi (Convolvulus prostratus), Shatavari (Asparagus racemosus), Mandukaparni (Centella Asiatica), Brahmi (Bacopa monnieri), Jyotishmati (Celastrus paniculatus) which are extensively used for their reputed effectiveness in C.N.S. conditions. This paper’s main aim is to explore C.N.S. Protective drugs or Medhya Rasayana mentioned in Ayurvedic classical textbooks concerning modern science mode of actions and to study the mechanism of the C.N.S. protective drugs. The source for this study is collected from classical Ayurvedic books and commentaries, modern medical science textbooks, and different articles from Pubmed, D.H.A.R.A., Google Scholar, etc. Various Medhya Rasayana mentioned in Ayurvedic texts have potent qualities to enhance memory and relieve medical illnesses related to C.N.S., whether it is related to mental or sensory problems. So, various safe and natural remedies are available in Ayurveda; long-term or short-term mental health can be recovered without any life-threatening complication.
Ayurvedic Aspect of Dhatusarata &Its Clinical Significance
Authors: Kisanrao Jadhao Akanksha , Chaple Dr. Jagruti
Published: May 2023

The conventional medical system known as Ayurveda was developed in India thousands of years ago. Ayurvedic specializations such as Agni, Prakruti, and Dhatusarata are the foundation for research, diagnosis, and treatment. Ayurveda states that the human body comprises Doshaa, dhatu, and mala. As Dosha is the structural and operational component of the human body, mala is to maintain the body's health and cleanliness, and dhatu gives strength to our body. They serve as the body's foundation. Seven dhatus are necessary for the human body's development and survival. The term ''SARA'' refers to the most crucial and refined portion of dhatu. The most purified or vital part of dhatus is known as Sara. Dhatu Sara pariksha serves as a useful mirror for evaluating the characteristics and purposes of dhatus. Dhatu sarata also determines the strength of a person. The description of dhatusarata [tissue excellence] has been given under Dashavidha pariksha [tenfold examination] in Charak Samhita, Viman sthana,8th chapter. Charak says one should commit to something other than a strong or weak foundation. Instead, it depends on Sara or the superior quality of dhatus. It is proven that certain people with small frames and slim builds can be powerful. Individuals with various dhatu sarata have varying aptitudes for particular tasks. Therefore, people should select a career by determining their dhatu sarata. Some quantitative criteria must be developed to evaluate these attributes by tissue excellence or dhatu sarata. One can determine a dhatu's true strength by evaluating Dhatu sarata. Dhatu sarata helps to determine the bala praman of an individual. For the enhancement of immunity, selection of career, antenatal care, and dietary regimen, dhatu sarata plays an important role. This study aims to elaborate on the concept of dhatu sarata and its application.
Ultrasound-Guided Percutaneous Dilatational Tracheostomy for Critically Ill Patients With COVID-19
Authors: Jeong Jun Yeong , Lee Seung Won , Park Ki Nam
Published: May 2023

Background and Objectives The global coronavirus disease 2019 (COVID-19) pandemic has had a major impact on healthcare, especially in the area of critical care due to the longer period of mechanical ventilation. Ultrasound-guided percutaneous tracheostomy (US-PDT) is considered a safe alternative method.Materials and Method Patients with severe COVID-19 hospitalized in the intensive care unit (ICU) who were on mechanical ventilation for 5 days or longer were evaluated for percutaneous dilational tracheostomy. The procedure was performed with personal protective equipment with powered air purifying respirator (PAPR) in the ICU isolated by negative pressure. Parameters such as mortality, incidence of infection to medical staff, major and minor complications were observed.Results The average time taken for US-PDT was 6.4 minutes. Five patients (27.8%) showed oxygen saturation of less than 90% due to apnea during tracheotomy, but there was no case of severe hypoxemia that required discontinuation or re-intubation. There was no COVID-19 infection of medical staff related to the procedure. A total of 9 patients (50%) died from COVID-19 pneumonia, and 1 patient (5.6%) was decannulated. There was no death due to US-PDT and no serious complications such as pneumothorax or accidental decannulation were observed.Conclusion As patients eligible for tracheostomy increased significantly due to the COVID-19 epidemic, US-PDT can be considered to be a useful technique for COVID-19 patients who require long-term mechanical ventilation. This technique can lower the risk of transmission to medical staffs who are at the forefront of being exposed to the risk of infection when an epidemic breaks out.
Tracheostomy in the Era of COVID-19 Pandemic
Authors: Park Jae Hong
Published: May 2023

Since COVID-19 pandemic, extreme care must be taken to not only tracheotomy, but also subsequent tube management so that medical staff and other patients can be protected from infectious aerosols from the patient. Numerous studies have been reported worldwide on the timing and indications for tracheotomy in COVID-19 patients since 2019. In this paper, we describe the issues to be considered not only during tracheostomy but also before and after procedure in COVID-19 patients with the literatures review.
Changes in medication initiation and selection patterns for gestational diabetes management
Authors: Pham Amelie , Shi Rena , Wiese Andrew D. , Spieker Andrew J. , Phillips Sharon E. , Adgent Margaret A. , Grijalva Carlos G. , Osmundson Sarah S.
Published: May 2023

Recent trends regarding GDM medication use have not been well described
in prior literature. We identified pregnant patients enrolled in
Tennessee Medicaid with a GDM diagnosis who a delivered in 2007 to 2019.
We studied initial GDM medication use by delivery year (overall and by
medication type). Over twenty percent of patients filled at least one
prescription for GDM medication in the study period, with a
significantly increasing prescribing trend over time. Starting in 2016,
metformin replaced glyburide as the most common medication prescribed,
which corresponds temporally with the emergence of evidence on the
safety and effectiveness of different oral hypoglycemic medications and
related changes in ACOG practice recommendations. These findings
highlight how practice patterns have potential to shift quickly in
response to evolving data.
Empirical averaging in deterministic optimal control
Authors: Chaplais Francois , Bernard Sandrine
Published: May 2023

A windowed averaged scheme is defined for general control systems. The
same method is used to average costs in optimal control problems (OCPs).
A numerical parameter α can be computed, which expresses the
distance between the original system and the averaged system in a weak
sense. The value of α is well defined for any system. Then, if we
use the optimal control of the averaged OCP in the original OCP, the
suboptimality of the control is bounded by an expression of the form C α
2 . This bound holds for any optimal control problem which satisfies the
Legendre-Clebsch condition and such that the convexity parameter
satifies a general inequation with respect to the numerical parameter
α.
Maternal genetic diversity, differentiation and phylogeny of wild yak and four domestic yak breeds in Qinghai, China inferred from mitochondrial Cytb variations
Authors: Xu Donghui , Li Ruizhe , Xu Yuhui , Guo Weixing , Li Wenhao , Chen Shengmei , Huang Weihua , Lei Chuzhao , Ma Zhijie
Published: May 2023

Yak (Bos grunniens) is a unique livestock animal originating from the
Qinghai-Tibet Plateau in China. In the current study, we investigated
the maternal genetic diversity, differentiation and phylogeny of wild
yak population and four domestic yak breeds (Qinghai-Gaoyuan, Huanhu,
Xueduo, and Yushu) in Qinghai, China by analyzing 166 mitochondrial
cytochrome b (Cytb) gene sequence variations. Our results indicated that
the haplotype and nucleotide diversities of wild yak were 0.883±0.044
and 0.004±0.002, while the total haplotype and nucleotide diversities of
four Qinghai domestic yak breeds were 0.646±0.040 and 0.003±0.001,
respectively. Among the four Qinghai domestic yak breeds, the haplotype
diversity was found to be highest in Yushu yak breed (Hd = 0.770±0.053),
while the lowest was recorded in Huanhu yak breed (Hd = 0.501±0.088).
Estimates of FST values showed a moderate genetic differentiation
between wild yak and Huanhu yak (FST = 0.058) as well as that between
Huanhu yak and Yushu yak breeds (FST = 0.052), but a weak genetic
differentiation was observed between the other yak breeds/populations
(-0.021＜FST＜0.037). Additionally, the clustering analysis based on RST
values showed that Xueduo yak and Huanhu yak were clustered into one
group, and each of the other three yak breeds/populations was separated
into one group, respectively. Overall, the clustering relationship
between wild yak and Yushu yak was closer. Maternal phylogenetic
analysis showed that wild yak and four local yak breeds/populations in
Qinghai represented in three maternal lineages (Mt-Ⅰ, Mt-Ⅱ, and Mt-Ⅲ),
indicating three maternal origins in yak. Our study would provide
valuable information for the conservation and utilization of wild yak
and Qinghai domestic yak breeds.