bluuebunny/crossref_metadata_2025 huggingface dataset:
O museu como lugar de memória: o conceito em uma perspectiva histórica
Authors: Vieira Guilherme Lopes
Published: June 2017

Os museus históricos, pela definição moderna, possuem reminiscências do passado que estão expostas no presente. Nesse sentido, são fontes históricas que devem ser exploradas através de sua potencialidade discursiva de criar narrativas históricas que procuram dar sentido ao passado. O questionamento sobre esse objeto tem que ser problematizado na chave que posiciona o presente como um dos fatores de construção do passado, na medida em que os sujeitos do presente resgatam os eventos que aconteceram, através de suas expectativas no presente. São arenas de disputas e devido ao seu aspecto simbólico, promotor de memórias, é válido apontar que são: “lugares de memória”. Dessa forma, devemos pensar o conceito de forma a historicizá-lo.Palavras-chave: Museu, Lugar de memória, Historiografia
A museologia social na prática comunitária: o caso da Casa da Memória Viva de Ceilândia, DF
Authors: Pereira Vinicius Carvalho
Published: June 2017

O artigo apresenta as ações desenvolvidas pela Casa da Memória Viva de Ceilândia junto à comunidade escolar, desta que é a mais populosa região administrativa do Distrito Federal. As atividades têm como foco a valorização da cultura e história locais, e principalmente da memória dos candangos, trabalhadores que participaram da construção de Brasília, que por vezes são deixadas de lado pela história oficial. Este museu comunitário os define como memória viva, que seriam pessoas portadoras de uma memória coletiva. Por meio de entrevistas com os colaboradores da instituição e a revisão bibliográfica especialmente da Nova Museologia, procuramos mostrar como esse museu desenvolveu desde a sua fundação trabalhos em conjunto com a comunidade local. Palavras-chave: Patrimônio, Memória, Ceilândia-DF, Candangos, Museologia
Schizophrenia and sense of coherence
Authors: Witkowska-Łuć Bogumiła
Published: June 2017

Cel pracy

Celem prezentowanych badań było poznanie zależności między poziomem poczucia koherencji (SOC) a poprawą objawową, rozumianą jako wskaźnik zdrowienia u pacjentów z zaburzeniami z kręgu schizofrenii.

Metoda

Grupę badaną stanowiło 134 pacjentów z diagnozą schizofrenii paranoidalnej (118 osób) lub zaburzeń schizoafektywnych (16 osób) leczonych w psychiatrycznych oddziałach całodobowych. Średni wiek osób badanych wynosił 36,22 lata (SD=8,51). Do oceny poczucia koherencji zastosowano Kwestionariusz Orientacji Życiowej A. Antonovsky. Poziom nasilenia objawów psychopatologicznych zbadano dwukrotnie na początku i na końcu hospitalizacji za pomocą Skali Objawów Pozytywnych i Negatywnych (PANSS). Wskaźnikiem zdrowienia hospitalizowanego pacjenta była różnica w nasileniu objawów psychopatologicznych podczas rozpoczynania oraz kończenia leczenia szpitalnego.

Wyniki

Z przeprowadzonych analiz wynika, że wyższemu poczuciu zrozumiałości (SOCCOM) sprzyja mniejsze nasilenie objawów negatywnych oraz ogólnej symptomatologii psychiatrycznej w PANSS podczas rozpoczynania hospitalizacji badanych pacjentów. Również osoby charakteryzujące się istotnie wyższym poczuciem koherencji ogólnej (SOC) prezentują wyraźnie mniejsze nasilenie objawów negatywnych podczas przyjęcia do szpitala. Wyniki badań pokazały, że wyższy poziom ogólnej koherencji (SOC) oraz wyższe poczucie zrozumienia (SOCCOM) współwystępują z mniejszą różnicą w zakresie nasilenia objawów psychopatologicznych.

Wnioski

Niniejszy artykuł stara się odpowiedzieć na ważne pytanie dotyczące roli poczucia koherencji w procesie zdrowienia pacjentów z zaburzeniami z kręgu schizofrenii. Sugeruje się, że współwystępowanie wyższego poczucia koherencji z większymi objawami negatywnymi oraz ogólnymi objawami psychopatologicznymi może stanowić u pacjentów kończących hospitalizację psychiatryczną przejaw osiąganego przez nich wglądu w chorobę, co można uznać za przejaw zdrowienia.
Journal Scan
Authors: Welyczko Nikki
Published: June 2017

Nikki Welyczko, Teacher Fellow and Principal Lecturer for Adult Nursing at the Faculty of Health and Life Sciences, De Montfort University, provides a brief overview of recently published nursing and health articles
Getting the best out of biological and biosimilar medicines for inflammatory bowel disease
Authors: Murphy Judith Anne
Published: June 2017

Although there is no cure for inflammatory bowel disease (IBD), its symptoms can be treated and remission induced using biological medicines, including the anti-TNF (tumour necrosis factor) drug infliximab. Biosimilars of infliximab have been made available in guidelines from the British Society of Gastroenterology and the National Institute for Health and Care Excellence, and they represent a considerable cost-saving opportunity for the NHS. The potential difficulties of switching infliximab to a biosimilar at a hospital can be overcome with a two-step implementation process. Emerging evidence on the factors influencing the variable effectiveness of these therapies is shaping best clinical practice, including studies on anti-TNF trough levels and anti-drug antibodies to infliximab, as well as the use of immunosuppressants. IBD nurse have the specialist knowledge and are in a unique position to measure progress, educate patients and encourage compliance, all of which helps optimise and prolong the effectiveness of biologic treatment.
Primary biliary cholangitis: symptoms, diagnosis and treatment
Authors: Mortimore Gerri
Published: June 2017

Primary biliary cholangitis (PBC), previously known as primary biliary cirrhosis, is a chronic but progressive disease that, over many years, causes damage to bile ducts, leading to cholestasis and, in some patients, cirrhosis. The rate at which PBC progresses varies from person to person, but significant damage takes decades to occur. It predominately affects women aged 40–60 years with a female to male ratio of 9:1, but can affect anyone from the age of 20. There is no cure for PBC other than liver transplant, but medications can be given to slow down disease progression and for the treatment of symptoms. Health professionals should monitor for complications, including the development of osteoporosis, vitamin deficiencies and liver cirrhosis, which caries the associated complications of portal hypertension, varices and ascites.
What we have achieved, where we are going
Authors: Greenslade Lynda
Published: June 2017

Lynda Greenslade, Hepatology Nurse Specialist and Committee Member of the British Liver Nurses' Forum, reflects on the forum's past and future
Stronger together: working to cure hepatitis C in Wales
Authors: Tomkinson Delyth
Published: June 2017

Delyth Tomkinson of Cardiff and Vale University Health Board looks at what has been done and what is still to do to eliminate hepatitis C in Wales by 2030
How care homes can make the most of the apprenticeship levy
Authors: Stevens Mark
Published: June 2017

The apprenticeship levy is now effect, with big businesses across the UK beginning to pay in. In this article, Mark Stevens explains what this levy is, what its intended purpose is, and how care homes can make use of the additional funding that it offers
What does the Care Quality Commission mean by ‘dignity’?
Authors: Frankova Helena
Published: June 2017

Despite widespread use, the term ‘dignity’ can be surprisingly hard to define—particularly when used by legal entities such as the Care Quality Commission. In this article, Helena Frankova explains what it is that the regulator expects when looking for dignity in care
Unions threaten to ‘intensify’ school funding campaign
Authors: Henshaw Pete
Published: June 2017

Conservative minority government faces renewed pressure over funding pledge, National Funding Formula and school costs
Four steps to a successful Ofsted
Authors: Rollett Stephen
Published: June 2017

To help you speak confidently to inspectors and understand what they are looking for, inspections specialist Stephen Rollett offers four practical steps…
Transmigration: the rise of flexible migration strategies as part of superdiversity
Authors: Geldof Dirk , Schrooten Mieke , Withaeckx Sophie
Published: June 2017

Superdiversity implies increasing diversity within diversity, including the rise of flexible migration strategies: complex migration trajectories implying serial cross-border mobility between two or more countries. The article explores transmigration in the two main superdiverse Belgian cities of Brussels and Antwerp, based upon in-depth interviews with Brazilian, Ghanaian and Moroccan transmigrants. The article analyses the social problems related to transmigration, how these problems transcend borders and challenge urban social work and social policies at different levels. It explores why transmigration requires forms of multilevel governance to deal with people living beyond borders in the EU.
Ambivalent apocalypse: The influence of the Book of Revelation in films and television
Authors: Baker Sarah
Published: June 2017

Apocalyptic texts are a popular genre of film and television that commonly present humanity as decimated, or threatened by decimation. Zombie apocalyptic themes have become popular and are seen in 28 Days later (Boyle, 2002), I am Legend (Lawrence, 2008), The Walking Dead (2010–present) and Fear the Walking Dead (2015–present). Other films feature further other end-of-the-world scenarios, including cataclysmic natural disasters, pestilence and invasion. There are numerous examples of post-apocalypse texts, including Night of the Living Dead (Romero, 1968), Mad Max 2 (Miller, 1981), Reign of Fire (Bowman, 2002), The Day After Tomorrow (Emmerich, 2004), Children of Men (Cuaron, 2006), Left Behind (Armstrong, 2014) and Knowing (Proyes, 2009). The focus of the narrative in these texts, whether it be zombie plague or extinction-level event asteroid, is on how the characters in these stories come to terms with disaster, either before or after the apocalyptic event. Other texts examine cataclysmic events that befall the earth, such as Deep Impact (Leder, 1998), The Day After Tomorrow (2004) or 2012 (Emmerich, 2009). All these texts highlight prevailing attitudes and cultural anxieties, and can also be discussed in terms of the differences in the representation of disaster after September 11, 2001. This article examines the connection of these texts to religious prophecies from the Bible (Revelation) and how popular culture texts demonstrate an ambivalent relationship to predictions of apocalypse.
Event Review
Authors: Vincent Alison
Published: June 2017

Food/Love/God: A Popular Culture Symposium, Popular Culture Research Centre, Auckland University of Technology, New Zealand, 4 February 2016
Précis
Authors: Elshahed Mohamed , Andersen Angela
Published: June 2017

‘WRITING HISTORIES OF NOW: MODERN AND CONTEMPORARY MIDDLE EAST ART AND ARCHITECTURE’, FORUM TRANSREGIONALE STUDIEN AND DEPARTMENT OF ART AND VISUAL HISTORY (IKB), HUMBOLDT UNIVERSITY, BERLIN, GERMANY, JULY 6–7, 2015

‘BEYOND THE MOSQUE: DIVERSE SITES OF MUSLIM
PRAYER’, UNIVERSITIES ART ASSOCIATION OF CANADA/L’ASSOCIATION D’ART DES UNIVERSITÉS DU CANADA ANNUAL CONFERENCE, MONTREAL, CANADA, OCTOBER 27–30, 2016
‘I could go on forever varying goblins’: Arthur Rackham designs Hansel and Gretel, Cambridge Theatre 1933
Authors: Lennox Patricia
Published: June 2017

During the Christmas theatre season, 1933, Arthur Rackham, noted for his fantasy illustrations, designed sets and costumes for Humperdinck’s opera Hansel and Gretel with a limited run at the Cambridge Theatre, 26 December to 27 January, 1934. Its producer Sydney Carroll and director Basil Dean were major figures in the London theatre and accustomed to working with professionals who were costume designers in the modern sense – unlike Rackham who was an illustrator hired to put his paintings onstage. Rackham was unfamiliar with the costume process and with the theatre in general and relied heavily on the more experienced Stella Mary Pearce (later Newton) to oversee the costumes’ construction and all final steps of the process. This article explores the extent to which Rackham’s experience – and product – as a neophyte designer can be reconstructed from available archival material that includes costume designs and correspondence.
Event Reviews
Authors: Pichou Myrsini , Barford Katie , Watt Fiona , Spencer Michael
Published: June 2017

Costume on Stage and Screen Symposium, Athens, 18 February 2017

Costume and Fashion In Context and Practice, University of Huddersfield, United Kingdom

Drawing Theatre: Pamela Howard – An Exhibition in The Crab Studio at Arts University Bournemouth, Curated by Rebecca Pride and Co-Curated by Sam Edwards, 22 March–22 April 2016

Review of The Vulgar: Fashion Redefined – Barbican Art Gallery, 13 October 2016–5 February 2017
Book Reviews
Authors: Osmond Suzanne , Comerford Chris , Fernandez Ester Mangas
Published: June 2017

Unbuttoned: The Art and Artists of Theatrical Costume Design, E. Shura Pollatsek (2017)

New York: Routledge, 176 pp.,

ISBN: 9781138919037, p/bk

 

The Superhero Costume: Identity and Disguise in Fact and Fiction, Barbara Brownie and Danny Graydon (2016)

London and New York: Bloomsbury Academic, 175 pp.,

ISBN: 978-1-4725-9590-4, p/bk

 

Mute Movements: A Collective Performance Art Journey Through Beirut, 2009–2014, Cornelia Krafft (2015)

Beirut: American University of Beirut Press, 303 pp.,

ISBN13: 9789953586175, h/bk
Hand in Glove: Reflections on a performed costume exhibition and the stories behind the garments
Authors: Connolly Mary Kate
Published: June 2017

This article details a conversation with seminal choreographer Lea Anderson, following her performed exhibition, Hand in Glove, which was staged at the V&A Museum, London, in April 2016. Hand in Glove featured over 300 costumes and accessories from the archives of Anderson’s two renowned contemporary dance companies, The Cholmondeleys and The Featherstonehaughs. These companies played a prominent role in the evolution of British contemporary dance from the 1980s until their dissolution in 2011. Costume and design have long been utilized as transformative elements within Anderson’s work, giving rise to characteristic intertextual layering, blurring of boundaries and the destabilization of hetero-normative representations of the dancing body. Hand in Glove occupied the Raphael Gallery at the V&A from 22 to 24 April 2016 with vignettes from ten of Anderson’s works performed by students from London Contemporary Dance School. The conversation with Anderson outlines the process involved in the mounting of Hand in Glove alongside accounts of her early works, and the influence which design and costume exert in her choreography. Anderson describes her collaborations with designers, in particular Sandy Powell and Simon Vincenzi, and the ways in which her work with costume has evolved over time. Reflections on the implications of the exhibition itself (as a rare opportunity to view costumes performed live within a gallery space) are thus placed within the wider context of her choreographic practice and visual influences.
Entheseal changes: the role of Portuguese research
Authors: Charlotte Charotte Yvette Henderson , Francisca Francisca Alves Cardoso
Published: June 2017

This paper presents a review of research in Portugal on entheseal changes (EC), widely used to record activity-patterns. This is explored chronologically and thematically, from the development of research initially testing of methods on identified collections, to a workshop in 2009, dedicated to EC, through to the recently published outputs of the working groups set up at that meeting. The role of individuals and the world class identified skeletal collections is also discussed. Key trends include the systematic development of recording methods, their testing and the interrogation of the interplay of biology and society in occupation. The recent outputs of all the working groups will inform current and future research, meaning that the Portuguese role in the study of entheses will be long-lived and continue to be of international significance. ResumoO presente trabalho apresenta uma revisão da investigação desenvolvida em Portugal no que concerne o tema das alterações das enteses (AE), que têm sido amplamente utilizadas para registar padrões de actividade em populações do passado. O tema é explorado cronológica e temática, desde o início da investigação em AE centrado no desenvolvimento de métodos testados em coleções osteológicas identificadas, até às recentes publicações dos vários grupos de trabalho que tiveram origem no workshop de 2009, inclusivamente. Será também discutida a importância dos investigadores e das coleções osteológicas identificadas no estudo das AE. Presentemente, as principais tendências no estudo das AE incluem o desenvolvimento de métodos de registo, a aferição da viabilidade e exequibilidade dos mesmos, e a discussão da relação entre biologia e sociedade associada ao conceito de ocupação. Os resultados dos grupos de trabalho reflectem o estado da arte actual e informam sobre investigações futuras evidenciando que o papel da investigação associada a Portugal no estudo das AE será de contínua significância internacional.
HUBUNGAN PERSEPSI SISWA TENTANG GURU MATEMATIKA DENGAN HASIL BELAJAR MATEMATIKA SISWA
Authors: Najichun Mohamad , Winarso Widodo
Published: June 2017

The purpose of this study was to know the relationship between student perception towards mathematics teacher with mathematics academic performace. The population of the study were all students of class VIII SMPN 8 Cirebon in the academic year 2014/2015, with the number of students 287 people. The sampling technique used proportional random sampling, and the sample size was 56 students. Data collection techniques used: 1) Questionnaire of Perceptions towards Mathematics teacher, and 2) The results of student mathematics learning test. The result of correlation analysis show no significant correlation between students perception towards teacher and academic performance (r= .155, p= .254).
Off-label Utilization of Antidepressants
Authors: Zullino Daniele Fabio , Schwartz Bruno , Bilancioni Romain , Baumann Pierre
Published: June 2017

While antidepressant prescription rules are established for approved indications by large-scale studies, off-label utilization naturally often lacks the validation by large scientific databases, and is at its best based on expert consensus. The aim of the present survey was to study the prescription habits of hospital psychiatrists with regard to antidepressants, comparing patients treated for depressions and anxiety disorder with patients receiving off-label antidepressant treatment. Methods: Data on drug use for this study were based on 6 reference days from April 1999 to November 2001 in the 98- bed psychiatric hospital of the University of Lausanne, Switzerland. The drug prescriptions of 174 patients were assessed. Results: Whereas the diagnosis did not influence the choice between newer or older antidepressants, patients presenting an anxiety disorder were 4.5 times more likely (p<0.05) and patients with other diagnoses 8 times more likely (p<0.001) to receive an antipsychotic comedication compared to patients whose primary diagnosis was a depressive disorder. Also, patients receiving concomitantly a nonbenzodiazepine hypnotic were less likely to be prescribed an older antidepressant (p<0.05). While patients with anxiety disorder and those with major depression received their antidepressants at comparable doses, patients with an off-label indication were treated preferentially with lower doses. Conclusions: The results of this survey suggest, that the prescribing hospital psychiatrists developed preferences with regard to the choice of the antidepressant class, which they then used for both registered and off-label indications. They then seemed to adapt the dose and the comedication according to the diagnosis, confirming the initial study hypothesis.
Symmetric and Asymmetric Solutions of p-Laplace Elliptic Equations in Hollow Domains
Authors: Kajikiya Ryuji
Published: June 2017

In the present paper, we study the p-Laplace equation in a hollow symmetric bounded domain. Let H and G be closed subgroups of the orthogonal group such that

H
⊊
G

{H\varsubsetneq G}

. Then we prove the existence of a positive solution which is H-invariant and G-non-invariant. Furthermore, we give several examples of H, G and Ω, and find symmetric and asymmetric solutions.
Rocking the Cradle: Making Petőfi a National Poet
Authors: Hites Sándor
Published: June 2017

The first part of this paper deals with how Sándor Petőfi (aka Alexander Petrovits) was elevated to the status of Hungarian national poet from an ethnically non-Magyar and otherwise controversial background (a dubious birthplace and mother tongue, a mysterious death). In a dynamic of longing and belonging, Petőfi himself was keen to shape and reshape the various layers of his ethno-cultural, regional and political identities, drawing on mythical and modern elements in equal measure, and, through his inclination for role playing, sometimes even ironizing the gestures of identity fashioning. The second part surveys the political appropriations and both material and symbolic rituals of cult formation regarding his life and works. In conclusion, I analyze the rhetorical rite of admitting an ‘alien’ into the national community that was performed in Petőfi’s critical afterlife, with a brief excursion into the similar or counter-gestures it provoked in Slovak nationalism.
Home in Biblical and Antwerp City Poems – A Journey
Authors: Vermeulen Karolien
Published: June 2017

Since 2003, the city of Antwerp has a poet laureate. Following the classical and Renaissance models, the Antwerp poet laureate writes, performs, and materializes poems for the city. Also in the Hebrew Bible, texts occur that qualify as city poems avant-la-lettre, even though the writers remain anonymous and the texts are part of a larger corpus with a different purpose. This article reads three Antwerp city poems alongside with biblical Psalm 137, in search for the poems’ constructions of cities as homes. The selected texts each introduce the city (i. e., Antwerp for the Antwerp city poems; Jerusalem and Babylon for the psalm) and its possible identification with a home place in ways that are conceptually and stylistically similar. The poems only differ in their final portrayals of the home, themselves connected to the different context of each poem. Throughout the texts the poets explore and question the spatial categories of ‘city’ and ‘home.’ The analysis reveals that being at home both in biblical and Antwerp city poems is connected to childhood, which allows redefining the urban space. The poems conceive cities as a mobile category that is internalized if being defined as home space. Stylistic interventions, in particular the use of inclusios and contrast, help creating and establishing the city-as-home-space in the selected city poems. The juxtaposition of old and new city poems sharing the same topic offers new insights into the textual construal of cities as homes, a process that proves to be similar for the three Antwerp city poems and the biblical psalm.
On Well-Posedness for a Piezo-Electromagnetic Coupling Model with Boundary Dynamics
Authors: Picard Rainer
Published: June 2017

We consider a coupled system of Maxwell’s equations and the equations of elasticity, which is commonly used to model piezo-electric material behavior. The boundary influence is encoded as a separate dynamics on the boundary data spaces coupled to the partial differential equations. Evolutionary well-posedness, i.e. Hadamard well-posedness and causal dependence on the data, is shown for the resulting model system.
Super-Exponentially Convergent Parallel Algorithm for a Fractional Eigenvalue Problem of Jacobi-Type
Authors: Gavrilyuk Ivan , Makarov Volodymyr , Romaniuk Nataliia
Published: June 2017

A new algorithm for eigenvalue problems for the fractional Jacobi-type ODE is proposed.
The algorithm is based on piecewise approximation of the coefficients of the differential equation with subsequent recursive procedure adapted from some homotopy considerations.
As a result, the eigenvalue problem (which is in fact nonlinear) is replaced by a sequence of linear boundary value problems (besides the first one) with a singular linear operator called the exact functional discrete scheme (EFDS).
A finite subsequence of m terms, called truncated functional discrete scheme (TFDS), is the basis for our algorithm.
The approach provides super-exponential convergence rate as

m
→
∞

{m\to\infty}

. The eigenpairs can be computed in parallel for all given indexes.
The algorithm is based on some recurrence procedures including the basic arithmetical operations with the coefficients of some expansions only.
This is an exact symbolic algorithm (ESA) for

m
=
∞

{m=\infty}

and a truncated symbolic algorithm (TSA) for a finite m.
Numerical examples are presented to support the theory.
Every rational Hodge isometry between two K⁢3K3 surfaces is algebraic
Authors: Buskin Nikolay
Published: June 2017

We present a proof that
for any Hodge isometry

ψ
:

H
2

⁢

(

S
1

,
ℚ
)

→

H
2

⁢

(

S
2

,
ℚ
)

{\psi\colon\hskip-0.853583ptH^{2}(S_{1},{\mathbb{Q}})\hskip-0.853583pt%
\rightarrow\hskip-1.13811ptH^{2}(S_{2},{\mathbb{Q}})}

between any two
Kähler

K
⁢
3

{K3}

surfaces

S
1

{S_{1}}

and

S
2

{S_{2}}

we can
find a finite sequence of K3 surfaces and analytic (2,2)-classes
supported on successive products, such that the isometry ψ is the
convolution of these classes.
The proof of this fact implies that for projective

S
1

,

S
2

{S_{1},S_{2}}

the class of ψ is algebraic.
This proves a conjecture
of I. Shafarevich [26].
Mosaikstruktur und soziale Schichtungen der Sprache in Gerhart Hauptmanns Die Ratten
Authors: Preußer Heinz-Peter
Published: June 2017

While Hauptmann’s final naturalistic drama is a highly self-reflective, autopoietic and modern work of art, it captivates audiences with its realistic qualities. The play molds social stratifications of articulation and speech, and its figures in their entirety, as radically constructed – and also inverses them. Given that the symbolism of high and low, bright and dark, tragedy and comedy are continuously subverted and suspended by one another,
Industrial Policy in Britain since 1970: Changing Values, Assumptions and Mechanisms
Authors: Chick Martin
Published: June 2017

This article examines the change in the fundamental assumptions underpinning industrial policy from the mid-1970s in Britain. It necessarily contrasts the broadly supply-side concerns of industrial policy from the mid-1970s with the more demand-side concerns of the earlier ‘Golden Age’ period from 1945. Where in the earlier period the emphasis in industrial policy was on capital investment and the role of government in compensating for perceived market inefficiency, from the late 1970s this emphasis shifted to the need to improve the flexibility and quality of supply-side factors allied to a more optimistic view of the ability of the market to secure efficient outcomes.
DHA reduces oxidative stress following hypoxia-ischemia in newborn piglets: a study of lipid peroxidation products in urine and plasma
Authors: Huun Marianne Ullestad , Garberg Håvard T. , Escobar Javier , Chafer Consuelo , Vento Maximo , Holme Ingar M. , Saugstad Ola Didrik , Solberg Rønnaug
Published: June 2017

Background:

Lipid peroxidation mediated by reactive oxygen species is a major contributor to oxidative stress. Docosahexaenoic acid (DHA) has anti-oxidant and neuroprotective properties. Our objective was to assess how oxidative stress measured by lipid peroxidation was modified by DHA in a newborn piglet model of hypoxia-ischemia (HI).

Methods:

Fifty-five piglets were randomized to (i) hypoxia, (ii) DHA, (iii) hypothermia, (iv) hypothermia+DHA or (v) sham. All groups but sham were subjected to hypoxia by breathing 8% O2. DHA was administered 210 min after end of hypoxia and the piglets were euthanized 9.5 h after end of hypoxia. Urine and blood were harvested at these two time points and analyzed for F4-neuroprostanes, F2-isoprostanes, neurofuranes and isofuranes using UPLC-MS/MS.

Results:

F4-neuroprostanes in urine were significantly reduced (P=0.006) in groups receiving DHA. Hypoxia (median, IQR 1652 nM, 610–4557) vs. DHA (440 nM, 367–738, P=0.016) and hypothermia (median, IQR 1338 nM, 744–3085) vs. hypothermia+DHA (356 nM, 264–1180, P=0.006). The isoprostane compound 8-iso-PGF2α was significantly lower (P=0.011) in the DHA group compared to the hypoxia group. No significant differences were found between the groups in blood.

Conclusion:

DHA significantly reduces oxidative stress by measures of lipid peroxidation following HI in both normothermic and hypothermic piglets.
Assessment of a novel mucolytic solution for dissolving mucus in pseudomyxoma peritonei: an ex vivo and in vitro study
Authors: Pillai Krishna , Akhter Javed , Morris David L.
Published: June 2017

Background

Pseudomyxoma peritonei (PMP) is difficult to treat. Intraperitoneal delivery of mucolytic solutions might potentially improve therapy, in addition to surgical cytoreduction and hyperthermic intraperitoneal chemotherapy.

Methods

Comparison of mucolytic effect of two formulations (control: bromelain 300 µg/mL+N-Acetylcystein 250 mM; test: bromelain 200 µg/mL+200 mM cysteamine) in vitro on a mucin producing cell lines (HT29) and ex vivo on mucus obtained from 18 PMP patients. Mucin plugs were classified according to their density into three categories: hard, semi hard and soft. Simulation of peritoneal washing ex vivo using a closed heated circulating pump.

Results

Solubilisation was faster with the test vs. the control formulation (90 vs. 180 min) for dissolving the soft mucin plugs (p < 0.05). The test solution was also more effective in dissolving the hard mucus plugs compared to control (82.5±2.74 % vs. 36.33±3.27 %). All mucin types disintegrated in simulated peritoneal washing. Cytotoxicity of the test solution on HT29 cell line was time-dependent.

Conclusions

The test formulation is more effective and faster than the control formulation in dissolving mucus plugs of various densities. Mucus plugs were all solubilised after 40 min in simulated peritoneal washing. This novel mucolytic formulation might pave the way for an effective and less invasive therapy of PMP in the future.
Determination of petroleum biodegradation by bacteria isolated from drilling fluid, waste mud pit and crude oil
Authors: Bilen Ozyurek Sezen , Seyis Bilkay Isıl
Published: June 2017

Objective

In this study, the aim was to isolate and identify bacterial strains in crude oil, drilling fluid and waste mud pit samples collected from the same oil field, determine the petroleum biodegradation and find the most effective bacteria in the samples in petroleum biodegradation.

Methods

The contents of crude oil, drilling fluid and waste mud pit samples were enriched in appropriate conditions. Upon identification of the isolated bacteria, the incubations in petroleum containing media were performed at 150 rpm at 30°C for 7 days. Petroleum biodegradations by bacteria were measured by using colorimetric, spectrophotometric and gravimetric methods.

Results

Bacillus cereus, Proteus mirabilis, Bacillus subtilis, Enterococcus faecalis were isolated from the crude oil sample; Bacillus subtilis subsp.spizizenii, Bacillus cereus, Enterococcus faecalis were isolated from the waste mud pit; and Proteus mirabilis, Klebsiella pneumoniae, Bacillus tequilensis, Bacillus axarquiensis and Enterobacter cloacae were isolated from the drilling fluid. Klebsiella pneumoniae was found to degrade 60% of the petroleum in the media and Bacillus axarquiensis degraded 51%.

Conclusion

In literature, no study was encountered showing biodegradation efficiencies of Bacillus axarquiensis which was isolated from the drilling fluid in our study. The use of Bacillus axarquiensis can contribute to advanced bioremediation studies.
Phoenicians in the Chronicler’s Jerusalem? Another Look at 1 Chronicles 15:13a
Authors: Rothstein David
Published: June 2017

למבראשונה in 1 Chr 15,13a gibt Lesern der Chronikbücher seit langem Fragen auf und hat zahlreiche Interpretationen und Emendationen hervorgebracht. Der vorliegende Artikel schlägt einen phönizischen/punischen Hintergrund vor. Dieser Vorschlag erlaubt es, den Konsonantenbestand des MT ohne textliche Emendationen beizubehalten, während er gleichzeitig die Wiedergabe in LXX
Geschlechterungleichheit in Führungspositionen: Der Einfluss von Arbeitsmarktsegregation und beruflichen Opportunitätsstrukturen
Authors: Granato Nadia
Published: June 2017

Frauen sind nach wie vor seltener in Führungspositionen zu finden als Männer. Bei der Suche nach den zugrundeliegenden Ursachen und Mechanismen dieser geschlechtsspezifischen Ungleichheit gilt es auch zu beachten, dass der deutsche Arbeitsmarkt zum einen durch eine deutliche Geschlechtersegregation gekennzeichnet ist. Zum anderen sind Leitungsfunktionen nicht gleichmäßig über das berufliche Spektrum verteilt. Somit stellt sich die Frage, inwieweit eine Überschneidung dieser beiden Phänomene und die daraus resultierenden Opportunitätsstrukturen zur beobachteten Chancenungleichheit beitragen. Empirisch zeigt sich, dass gerade in höher qualifizierten Tätigkeiten ein deutlicher Teil der geschlechtsspezifischen Nachteile auf diese strukturellen Gegebenheiten zurückzuführen ist. Im Bereich der qualifizierten Berufe trifft dies allerdings nicht durchgängig zu. Hier trägt die berufliche Verteilung von Frauen und Männern nur teilweise zur Erklärung von Ungleichheitsmustern bei.
A normal genetic variation modulates synaptic MMP‐9 protein levels and the severity of schizophrenia symptoms
Authors: Lepeta Katarzyna , Purzycka Katarzyna J , Pachulska‐Wieczorek Katarzyna , Mitjans Marina , Begemann Martin , Vafadari Behnam , Bijata Krystian , Adamiak Ryszard W , Ehrenreich Hannelore , Dziembowska Magdalena , Kaczmarek Leszek
Published: June 2017

Matrix metalloproteinase 9 (MMP‐9) has recently emerged as a molecule that contributes to pathological synaptic plasticity in schizophrenia, but explanation of the underlying mechanisms has been missing. In the present study, we performed a phenotype‐based genetic association study (PGAS) in > 1,000 schizophrenia patients from the Göttingen Research Association for Schizophrenia (GRAS) data collection and found an association between the MMP‐9 rs20544 C/T single‐nucleotide polymorphism (SNP) located in the 3′untranslated region (UTR) and the severity of a chronic delusional syndrome. In cultured neurons, the rs20544 SNP influenced synaptic MMP‐9 activity and the morphology of dendritic spines. We demonstrated that Fragile X mental retardation protein (FMRP) bound the MMP‐9 3′UTR. We also found dramatic changes in RNA structure folding and alterations in the affinity of FMRP for MMP‐9 RNA, depending on the SNP variant. Finally, we observed greater sensitivity to psychosis‐related locomotor hyperactivity in Mmp‐9 heterozygous mice. We propose a novel mechanism that involves MMP‐9‐dependent changes in dendritic spine morphology and the pathophysiology of schizophrenia, providing the first mechanistic insights into the way in which the single base change in the MMP‐9 gene (rs20544) influences gene function and results in phenotypic changes observed in schizophrenia patients.
Diabetes insipidus is an unfavorable prognostic factor for response to glucocorticoids in patients with autoimmune hypophysitis
Authors: Lupi Isabella , Cosottini Mirco , Caturegli Patrizio , Manetti Luca , Urbani Claudio , Cappellani Daniele , Scattina Ilaria , Martino Enio , Marcocci Claudio , Bogazzi Fausto
Published: June 2017

Introduction

Autoimmune hypophysitis (AH) has a variable clinical presentation and natural history; likewise, its response to glucocorticoid therapy is often unpredictable.

Objective

To identify clinical and radiological findings associated with response to glucocorticoids.

Design and methods

12 consecutive patients with AH, evaluated from 2008 to 2016. AH was the exclusion diagnosis after ruling out other pituitary masses and secondary causes of hypophysitis. Mean follow-up time was 30 ± 27 months (range 12–96 months).

Results

MRI identified two main patterns of presentation: global enlargement of the pituitary gland or panhypophysitis (n = 4, PH), and pituitary stalk abnormality only, or infundibulo-neuro-hypophysitis (n = 8, INH). Multiple tropin defects were more common in PH (100%) than those in INH (28% P = 0.014), whereas diabetes insipidus was more common in INH (100%) than that in PH (50%; P = 0.028). All 4 PH and 4 out of 8 INH were treated with glucocorticoids. Pituitary volume significantly reduced in all PH patients (P = 0.012), defective anterior pituitary function recovered only in the two patients without diabetes insipidus (50%) and panhypopituitarism persisted, along with diabetes insipidus, in the remaining 2 (50%). In all INH patients, either treated or untreated, pituitary stalk diameter reduced (P = 0.008) but diabetes insipidus persisted in all.

Conclusions

Glucocorticoid therapy may improve anterior pituitary function in a subset of patients but has no effect on restoring posterior pituitary function. Diabetes insipidus appears as a negative prognostic factor for response to glucocorticoids.
Un diálogo entre marxistas y liberales
Authors: Lariguet Guillermo
Published: June 2017

En esta nota crítica examino el libro  de Fernando Lizárraga Marxistas y Liberales. Mis objetivos en la nota son tres. En primer lugar, ofrecer una reconstrucción descriptiva de los principales aspectos de la estructura y contenido del libro. Segundo, discutir brevemente tres cuestiones. Estas cuestiones son, primero, la naturaleza del diálogo entre marxistas y liberales desde la perspectiva del filósofo francés Louis Althusser. Segundo, la relación entre la fundamentación normativa de los principios de justicia y la cuestión empírica de su aplicación al  mundo real. Tercero, las críticas del marxismo al utilitarismo clásico de Bentham. En tercer y último lugar, describo el conjunto de creencias y emociones que la lectura del libro de Lizárraga me han transmitido.
La ética del voto y el gobierno de los pocos. A propósito de Jason Brennan y John Stuart Mill
Authors: Gil Martín Francisco Javier
Published: June 2017

En este artículo se examinan los argumentos de Jason Brennan acerca de los deberes morales relativos a nuestra práctica de votar, argumentos que reflejan un enfoque epistocrático de la política y elaboran una concepción de la abstención a cuatro bandas: como una elección personal, una responsabilidad moral, un deber legalmente exigible y una obligación decidida por sorteo. El contraste con temas análogos en John Stuart Mill ayuda a iluminar las ambivalencias postdemocráticas y el solapado paternalismo trás del rechazo de Brennan al voto en masa y a la democracia electoral. Un enfoque deliberativo sobre la abstención inspirado en Mill permite también cuestionar el supuesto de las sucesivas propuestas de Brennan de que no hay una pérdida significativa en pasar por alto la relevancia política de la abstención cualificada.
Professional Training of Future Teachers in the System of Continuous Education
Authors: Matveieva Nataliia
Published: June 2017

The author analyzes the features of training future teachers in the system of continuous education, emphasizes the need for systematic, focused, continuous improvement, and self-fulfillment. The article noted that in preparation for future professional activities in higher education are formed the basic skills and accumulated knowledge and experience that will serve as an effective teacher’s growth, his creative work, the desire for further improvement. The author concludes that continuous education today serves not only the guarantee of the state and society, but also personal needs of each person
Psychosocial and Pedagogical Means of Reduction of Hyper Dynamic Manifestations Syndrome Within the Affective Personality Disorder
Authors: Novitska Liana
Published: June 2017

The problem of correction of affective personality disorders (for example, reducing the manifestations of hyper dynamic syndrome), analyzes the main approaches to its solution. We determined the causes and forms of attention deficit disorder with hyperactivity. To characterize the basic correction means reducing the manifestations of hyper dynamic behavior, which includes two areas with different content and psycho social and recreational components. The first direction is connected with the conduct of an individual or group psycho-correction work; the second – social and recreational include tasks aimed at providing social and psychological support to the individual. It is shown that the problem of hyperactive behavior is determined by the individual variability and natural features caused by human development. Psychological studies suggest the importance of external, social factors, primarily adequate forms of organization and communication, the influence of family relations on the manifestations of hyperactivity. It is shown that the implementation of psycho-pedagogical bases of overcoming hyperactivity leads to increased self-esteem, developing the ability to plan and predict their own behavior and, as a consequence – the disclosure of the individual adaptation possibilities
Readiness of Future Music Teachers on the Basis of the Praxeology Approach: Essence, Structure, Development Criteria
Authors: Provorova Ievgeniia
Published: June 2017

The article analyzes the essence of the concept “methodical readiness of future music teacher on the basis of praxeology approach”. The paper shows the result of methodical preparation in higher pedagogical educational institution that reflects the system of needs, motivations, imagination, values, the ability to broadcast or create innovations for improvisation, to forecast the results of own activities; high level of informative knowledge in the field of music art and techniques, skills of use own voice, facial expressions, gestures, techniques and methods for generating and analyzing ideas, successfully apply praxeology educational technologies that maintain the success of musical and pedagogical (singing) activity. The researcher outlined motivationally-valuable, emotional and volitional, cognitive-reflective, creative-projective, behavioral, personally-resulted, organizationally-communicative components, criteria and indicators of analyzed phenomenon
Humor as a Part of Interpersonal Communication
Authors: Karpenko Hanna
Published: June 2017

The article deals with the description and analysis of humor, irony, sarcasm in our life. Different points of view on humor are presented. Theories of the origin of humor (relief, incongruity, superiority) are described. It’s proved that humor is a part of interpersonal communication and it is irreplaceable characteristic and the quality people always seek in other ones. Some features of humor and the categories of irony (verbal, situational and dramatic) are demonstrated. The advantages of using humor by teachers in the classroom are stated. Some episodes from the lives of students in which they use humor, irony and sarcasm are presented. It’s stressed that people were born with the gift of laughter that lifts their spirits, makes them feel happy. The article states that a sense of humor is a good characteristic that helps people to live happily, to stay younger, to endure problems and to influence other people positively
Criteria, Indicators and Development Levels of Personal and Professional Component of Primary School Teacher’s Social Competence in the System of Postgraduate Pedagogical Education: Theoretical Analysis
Authors: Varetska Оlena
Published: June 2017

The author focuses on the problem of the development of primary school teacher’s social competence in the conditions of primary education modernization, proves the necessity of the research and substantiates the criteria, indicators and levels of the specified competency development in the system of postgraduate pedagogical education; illustrates the tools of personal and professional component
Psychological Foundations of Spiritual and Personal Development of Students in the Structure of Social Mobility
Authors: Zavatskyi Yurii , Toba Marianna
Published: June 2017

The article deals with the problem of spiritual and personal development of the individual, which is relevant both in science and in social practice. The urgency of this problem is due to reasons of several types: First, the current youth committed to the fullest identify and implement their capacity as seeks to “meet” the modern world as an "equal partner"; secondly, to modern human problem of implementation of all its possibilities connected with quite influential social trends of today derived from “the need for self-actualization”, which has acquired the status of social need and value in modern society. The research shows modern approach to spiritual and personal development of young people. We presented the idea of an integrated approach to nature, mechanisms spiritual and personal development of young people. It was established that the socio-psychological meaning of spiritual and personal development of students is the realization of cognitive-intellectual, sensory, emotional, volitional, creative potential, the implementation of advanced qualitative and quantitative change in the value orientations and actions that result in achieving mental integrity and harmony. We established that this can be interpreted as a form of art, because it is individual knowledge of nature, the discovery of own possibilities and implementation
The Traditions and Beliefs of Highlanders as a Means of Self-Identity and Ethnos Preserving
Authors: Chervinska Inna , Nykorak Jaroslav , Chervinskyi Andrii
Published: June 2017

The article reveals the peculiarities of the ethnic identity of pupils in school socio-cultural space in the mountain school of Carpathian region. In general, the term “region” as socio-cultural space is generally accepted and a regional approach is an effective form of studying the problems of social and cultural transformations of the country as a whole as well as its socio-cultural educational and other spaces. Such methodological regulation helps to consider national (state) socio-cultural space as a unity of regional spaces. The decisive in resolving the existing contradictions between human activities and the nature of must become all the methods and tools that can help to form the basic culture and human consciousness is that will form the basis for the formation of the ethnic identity of the person
Methodological Problems of Modern Pedagogy
Authors: Vasianovych Hryhoriy , Mushketa Radoslav
Published: June 2017

The article analyses the nature and the content of the term “methodology”, and concludes that so far there is no clear approach to the notion definition. Much attention is paid to determine the relationship between methodology and science, and to reveal dialectical aspects of this relationship. The author studies the main factors of methodology influence on improving teaching reality and pedagogical activity, and defines the role of methodology in forming the content of pedagogical education. It is proved that the improvement of the educational process and study of its main components depends on methodological culture of a teacher