bluuebunny/crossref_metadata_2025 huggingface dataset:
Current status of the problem of thermal Casimir force
Authors: Klimchitskaya G. L. , Mostepanenko V. M.
Published: February 2022

The problem of thermal Casimir force, which consists in disagreement of theoretical predictions of the fundamental Lifshitz theory with the measurement data of high precision experiments and some peculiar properties of the Casimir entropy, is reviewed. We discuss different approaches to the resolution of this problem proposed in the literature during the last 20 years. Particular attention is given to the role of the effects of spatial dispersion. The recently suggested nonlocal Drude-like permittivities which take proper account of the dissipation of conduction electrons and bring the predictions of the Lifshitz theory in agreement with experiment and requirements of thermodynamics are considered. The prospects of this approach in the ultimate resolution of the problem of thermal Casimir force are evaluated.
Quantum corrections to soliton energies
Authors: Graham N. , Weigel H.
Published: February 2022

We review recent progress in the computation of leading quantum corrections to the energies of classical solitons with topological structure, including multi-soliton models in one space dimension and string configurations in three space dimensions. Taking advantage of analytic continuation techniques to efficiently organize the calculations, we show how quantum corrections affect the stability of solitons in the Shifman–Voloshin model, stabilize charged electroweak strings coupled to a heavy fermion doublet, and bind Nielsen–Olesen vortices at the classical transition between type I and type II superconductors.
Imprints of new physics in Λb → Λ∗l+l− decay in nonuniversal Z′ model
Authors: Biswas S. , Mahata S. , Nayak B. P. , Sahoo S.
Published: February 2022

Inspired by various updated tantalizing results of LHCb on baryonic sector we study the [Formula: see text] decay in nonuniversal [Formula: see text] model. We present the fourfold angular distributions of the decay in terms of transversity amplitudes. We structure the observables: differential branching ratio, lepton side forward–backward asymmetries and polarization fractions in terms of the transversity amplitudes and incorporate the new physics (NP) terms in it. We reduce the number of the form factors using the improved Isgur–Wise relations. We study the observables in the Standard Model (SM) as well as in nonuniversal [Formula: see text] model. The predicted values are very interesting for the high energy physics community and results might provide prominent footprints of NP.
First-Order All-Pass Filters Comprising One Modified DDCC-
Authors: Abaci Ahmet , Alpaslan Halil , Yuce Erkan
Published: February 2022

In this paper, two new first-order voltage-mode all-pass filters (APFs) are proposed. Each of the proposed APFs comprises a single modified DDCC-, and has high input impedance. The first and second APFs can provide first-order noninverting and inverting APF responses, respectively. As passive elements, the first APF comprises two grounded capacitors, and a floating resistor while the second one uses a grounded resistor, a floating resistor and a grounded capacitor. However, both of the APFs suffer from a matching problem. Two quadrature oscillators (QOs) obtained from the APFs are presented. Simulations of the APF and QO circuits are fulfilled via the SPICE program. Besides, diverse experiments for the APFs are made to verify the performances.
Collapsing axial system and f(𝒢,T) gravity
Authors: Awais Sadiq M. , Manzoor Rubab , Mumtaz Saadia
Published: February 2022

The motive of this paper is to investigate the evolution of dissipative axially symmetry collapsing fluid in the presence of dark sources. For this purpose, we use the modified Gauss–Bonnet gravity as an exotic energy candidate. We formulate the dynamical variables and investigate the impacts of dark sources upon the heat dissipation and pressure anisotropy. We find scalar functions through orthogonal decomposition of Riemann tensor. The physical behavior of these scalars has been examined for matter as well as dark source configurations. Moreover, we develop a set of EEs related to the evolution of dynamical variables, heat transport equation, Weyl tensor and super-Poynting vector. These equations discuss collapse features like thermodynamics, density inhomogeneity and gravitational radiations in presences of exotic terms. It has been shown that the dark source terms have an effect on the thermodynamics of the system, evolution of kinematical variables and density inhomogeneity. The exotic terms can generate repulsive radiations which can induce cosmic expansion. Finally, the physical significance of modified Gauss–Bonnet gravity is explored in association to the stellar 4U1820-30.
Global well-posedness for volume–surface reaction–diffusion systems
Authors: Morgan Jeff , Tang Bao Quoc
Published: February 2022

We study the global existence of classical solutions to volume–surface reaction–diffusion systems with control of mass. Such systems appear naturally from modeling evolution of concentrations or densities appearing both in a volume domain and its surface, and therefore have attracted considerable attention. Due to the characteristic volume–surface coupling, global existence of solutions to general systems is a challenging issue. In particular, the duality method, which is powerful in dealing with mass conserved systems in domains, is not applicable on its own. In this paper, we introduce a new family of [Formula: see text]-energy functions and combine them with a suitable duality method for volume–surface systems, to ultimately obtain global existence of classical solutions under a general assumption called the intermediate sum condition. For systems that conserve mass, but do not satisfy this condition, global solutions are shown under a quasi-uniform condition, that is, under the assumption that the diffusion coefficients are close to each other. In the case of mass dissipation, we also show that the solution is bounded uniformly in time by studying the system on each time-space cylinder of unit size, and showing that the solution is sup-norm bounded independently of the cylinder. Applications of our results include global existence and boundedness for systems arising from membrane protein clustering or activation of Cdc42 in cell polarization.
The classification of sharp permutation groups of type {0,4}
Authors: Adhami S. Roghayeh , Brozovic Douglas P.
Published: February 2022

The purpose of this paper is a classification of the non-geometric sharp permutation groups of type [Formula: see text]. This, together with the work of Maund on geometric groups, yields a complete classification of sharp permutation groups of type [Formula: see text].
Conservation laws in gauge gravity theory
Authors: Obukhov Yuri N.
Published: February 2022

We analyze the conservation laws in the gauge gravity theory which are derived for the general class of gravitational models with the action invariant under the local Poincaré and the diffeomorphism group. The consistent Noether-Lagrange formalism is developed, revealing the important role of the auxiliary Goldstone and Stueckelberg fields, with the help of which we construct the composite gauge fields that have a clear geometrical and physical meaning.
Generalizing the constant-roll condition in scalar inflation
Authors: Oikonomou V. K.
Published: February 2022

In this work, we generalize the constant-roll condition for minimally coupled canonical scalar field inflation. Particularly, we shall assume that the scalar field satisfies the condition [Formula: see text], and we derive the field equations under this assumption. We call the framework extended constant-roll framework. Accordingly, we calculate the inflationary indices and the corresponding observational indices of inflation. In order to demonstrate the inflationary viability, we choose three potentials that are problematic in the context of slow-roll dynamics, namely, chaotic, linear power-law and exponential inflation, and by choosing a simple power-law form for the smooth function [Formula: see text], we show that in the extended constant-roll framework, the models are compatible with the latest 2018 Planck constraints on inflation. We also justify appropriately why we called this new framework extended constant-roll framework, and we show that the condition [Formula: see text] is equivalent to the condition [Formula: see text], with the latter condition being a simple generalization of the constant-roll condition. Finally, we examine an interesting physical situation, in which a general extended constant-roll scalar field model is required to satisfy the cosmological tracker condition used in quintessence models. In contrast to the slow-roll and ordinary constant-roll cases, in which case the tracker condition is not compatible with neither the slow-roll or the ordinary constant-roll conditions, the extended constant-roll condition can be compatible with the tracker condition. This feature leads to a new inflationary phenomenological framework, the essential features of which we develop in brief. The main feature of the new theoretical framework is that the function [Formula: see text] and the potential [Formula: see text] are no longer free to choose, but these are directly functionally related.
Molecular Dynamics Simulations of Nanoindentation of CuNi Alloy
Authors: Han Ben , Zhang Can , Shi Mingxing
Published: February 2022

In this paper, molecular dynamics was used to simulate the indentation process of copper–nickel (CuNi) alloy. Its mechanical properties and behaviors were investigated focusing on factors such as indentation velocity, test temperature and crystal orientation. Generally speaking, dislocation generations and slips, stacking faults, extended dislocations and deformation twins, one or more of them come into play the dominant role during plastic deformation, which in return leads to an improved or reduced hardness of CuNi alloy. Specifically, simulations and analyses reveal the following: (1) its hardness [Formula: see text] increases with [Formula: see text] increasing, but the reduced elastic modulus [Formula: see text] is not sensitive to [Formula: see text]; when it comes to test temperature [Formula: see text], both [Formula: see text] and [Formula: see text] are reduced at elevated [Formula: see text]; besides, the CuNi alloy along [Formula: see text] owns the highest [Formula: see text] and [Formula: see text], the value of [Formula: see text] along [Formula: see text] is slightly smaller than that along [Formula: see text] (2) the dislocation density [Formula: see text] varies severely in the early stage of indentation and then generally levels off when indentation depth reaches approximately 1.5[Formula: see text]nm; by and large, its hardness and dislocation density follow the classical Taylor hardening model and the hardening coefficient does depend on the three factors; (3) the plastic-zone size parameter [Formula: see text], when [Formula: see text] or equivalently [Formula: see text] can be taken as constant roughly 4.0 except in the case of indentation along [Formula: see text], in which it is about 5.7.
重建通道
Authors: 王 纯强
Published: February 2022

海外出生的华人移民后代为何会致力于与中国重新建立联系乃至返回中国？针对这个议题，学者们多将之归结于移民对祖籍地的原生情感或是基于对中国的民族主义。史学家孔飞力近期提出的“通道”概念却迫使我们将关注点聚焦于移民与中国往来背后的个人和社会经济因素。本文主要通过一名第三代海峡华人林文庆 (1869—1957) 来探讨海外华人与中国的关系。林文庆一方面重建与中国之间的联系通道，最终也返回厦门工作，但另一方面他也安于自己的混合血统以及是身处海外的华人的事实。本文强调林文庆之所以会对中国与其文化产生认同，是因应新加坡当时社会经济状况的变迁，认为它们将有助于确保海峡华人群体在当地的社会地位与持续繁荣。
IMPLICATIONS OF CARBON TRADE WITH ENDOGENOUS PERMITS FOR POST-PARIS CLIMATE AGREEMENTS
Authors: YU SHUMIN , WU YINHAO
Published: February 2022

With an intention to pursue an international carbon trade system and to find its implications for post-Paris climate agreements, we develop in this paper an international climate policy game with a mitigation agreement and a carbon market with endogenous permits choice. We explore incentives in a game-theoretic model for market participation, incentives to join a mitigation agreement and the interlinkages between the two. Our numerical results show that the presence of a carbon market with endogenous permits choice could improve the single mitigation coalition by engaging more regions with climate mitigation actions and inducing the Pareto improvement to some specific mitigation coalitions. Yet, more alternative strategic options offered by carbon trade are a disincentive for some regions to join a mitigation coalition. Nonetheless, this minor negative influence can be overwhelmed by more involvement in climate actions, higher global mitigation level and welfare gains resulted from an extra carbon market.
Rapid screening and probabilistic estimation of the potential for CO
2
-EOR and associated geological CO
2
storage in Colombian petroleum basins
Authors: Yáñez Angarita Edgar Eduardo , Núñez-López Vanessa , Ramírez Ramírez Andrea , Castillo Monroy Edgar , Faaij Andre
Published: February 2022

Estimating the oil recovery potential using CO
2
(CO
2
-EOR) at a national level is resource-intensive at a scale that is not usually available. The aim of this study is two-fold: first, the potential for CO
2
storage and enhanced oil recovery (EOR) in Colombia is evaluated; and, second, the results from two different calculation methods (stochastic and deterministic) are compared when there is lack of information for a quick screening of suitable oilfields. The deterministic approach is based on expert insight and data found in the literature; while, the stochastic uses statistical data from two different databases (commercial and simulation-based results) to run a Monte Carlo simulation. Potential estimates based on typical values from the literature (deterministic) results in 277 MMbbl (million barrels) of oil and 36 Mt (million tonnes) of CO
2
. In contrast, a probabilistic-based method using a wide simulation database (stochastic) provides higher values of 690 MMbbl of oil and 203 Mt of CO
2
. Results using simulation-based and commercial project data also show significant differences. The volume of CO
2
injected, which affects the recovery factor, is usually 100% hydrocarbon pore volume (HCPV) in simulation, while commercial projects have nowadays regularly increased from 30% to exceed the 100% threshold. A combination of these approaches avoids a resource-intensive estimation process and effectively provides a more realistic picture of the feasibility of applying CO
2
-EOR technologies.

Thematic collection:
This article is part of the Geoscience for CO
2
storage collection available at:
https://www.lyellcollection.org/cc/geoscience-for-co2-storage
Camaroptera: A Long-range Image Sensor with Local Inference for Remote Sensing Applications
Authors: Desai Harsh , Nardello Matteo , Brunelli Davide , Lucia Brandon
Published: February 2022

Batteryless image sensors present an opportunity for long-life, long-range sensor deployments that require zero maintenance, and have low cost. Such deployments are critical for enabling remote sensing applications, e.g., instrumenting national highways, where individual devices are deployed far (kms away) from supporting infrastructure. In this work, we develop and characterize Camaroptera, the first batteryless image-sensing platform to combine energy-harvesting with active, long-range (LoRa) communication. We also equip Camaroptera with a Machine Learning-based processing pipeline to mitigate costly, long-distance communication of image data. This processing pipeline filters out uninteresting images and only transmits the images interesting to the application. We show that compared to running a traditional
Sense-and-Send
workload, Camaroptera’s
Local Inference
pipeline captures and sends upto

\( 12\times \)

more images of interest to an application. By performing
Local Inference
, Camaroptera also sends upto

\( 6.5\times \)

fewer uninteresting images, instead using that energy to capture upto

\( 14.7\times \)

more new images, increasing its sensing effectiveness and availability. We fully prototype the Camaroptera hardware platform in a compact, 2 cm

\( \times \)

3 cm

\( \times \)

5 cm volume. Our evaluation demonstrates the viability of a batteryless, remote, visual-sensing platform in a small package that collects and usefully processes acquired data and transmits it over long distances (kms), while being deployed for multiple decades with zero maintenance.
The Potential of Jatropha variegata Fruits as a Natural Contraceptive: Antifertility Activity and Phytochemical Analysis
Authors: Alhaj Wahibah Taher , Moharram Bushra Abdulkarim , Al-Maqtari Tareq , Al-Mahbashi Hassan M. , Al-Doaiss Amin A.
Published: February 2022

Background. Jatropha variegata (family, Euphorbiaceae) is native to Yemen, where it is commonly known as the Ebki shrub. The fruits of the plant are traditionally ingested by local women as a natural method of contraception. This study was undertaken to investigate the phytochemical content of the methanol extract of J. variegata fruits and to evaluate its antifertility potential. Methods. Isolation of the chemical constituents was performed by chromatographic techniques, and the chemical structures of these compounds were identified by spectroscopy. The antifertility activity of the methanol extract was assessed in two experimental rat models to explore both the anti-implantation and the estrogenic/antiestrogenic activities in females. In these models, the number of successful implants, the size of litter, and body/ovary weights were all recorded. The development of ovarian follicles was also monitored via histological staining. Results. Phytochemical work on the fruit extract of J. variegata led to the isolation of two oils (JF1 and JF2) and methyl elaidate. GC-MS analysis of the JF1 oil revealed that the major chemical constituents were fatty acid esters (43.77%), hydrocarbon alkanes (20.65%), and terpenoids (4.65%), while terpenoids (28.8%), fatty acids and their esters, (29.47%), and phytosterol (10.49%) were the major components found in the JF2 oil. The methanol extract of J. variegata fruit exhibited 50% and 93% abortifacient activity at 150 and 300 mg/kg doses, respectively. The extract also showed significant estrogenic activity as evidenced by the increase in rat ovary weight at a dose of 300 mg/kg compared to the control group. Histological analyses further confirmed this estrogenic activity. Conclusions. J. variegata fruits possess an antifertility activity that appeared to result from its antiembryo implantation potential and from its estrogenic activity. The bioactive constituents involved in these activities may need to be further explored and exploited in the pursuit of newer contraceptives.
Evaporation Rate Prediction Using Advanced Machine Learning Models: A Comparative Study
Authors: Al Sudani Zainab Abdulelah , Salem Golam Saleh Ahmed
Published: February 2022

Accurately estimating the amount of evaporation loss is necessary for scheduling and calculating irrigation water requirements. In this study, four machine learning (ML) modeling approaches, extreme learning machine (ELM), gradient boosting machine (GBM), quantile random forest (QRF), and Gaussian process regression (GPR), have been developed to estimate the monthly evaporation loss over two stations located in Iraq. Monthly climatical parameters have been used as an input variable for simulating the evaporation rate. Several statistical measures (e.g., mean absolute error (MAE), correlation coefficient (R), mean absolute percentage error (MAPE), and modified index of agreement (Md)), as well as graphical inspection, were used to compare the performances of the applied models. The results showed that the GBM model has much better performance in predicting monthly evaporation over two stations compared to other applied models. For the first case study which was in Diyala, the results showed a prediction enhancement in terms of MAE and RMSE by 7.17%, 21.01%; 16.51%, 15.74%; and 23.14%, 26.64%; using GBM compared to ELM, GPR, and QRF, respectively. However, for the second case study (in Erbil), the prediction enhancement was improved in terms of reduction of MAE and RMSE by 10.88%, 9.24%; 15.24%, 5%; and 16.06%, 15.76%; respectively, compared to ELM, GPR, and QRF models. The results of the proposed GMBM model can therefore assist local stakeholders in the management of water resources.
Transverse Myelitis Associated with Cryptococcus neoformans in an Immunocompetent Patient
Authors: Villafuerte David B. , Passeri Marco F. , Qazi Rayan , Baireddy Moulika , Sanchez Fernando L.
Published: February 2022

Cryptococcus neoformans is a microscopic fungus that despite its pervasiveness in the environment rarely causes infection in immunocompetent patients. In immunosuppressed patients, infections involving the central nervous system (CNS) usually present as meningitis or meningoencephalitis. Cryptococcal infections are known to cause significant morbidity and mortality in immunosuppressed patients as it is difficult to eradicate even with adequate antifungal treatment. A 44-year-old Hispanic male presented to the hospital with headache, progressive urinary retention, neck and back pain, and right upper and bilateral lower extremity weakness for five days. Imaging revealed small foci in the white matter and revealed diffuse abnormal signal involving the cervical medullary junction extending up to the thoracic spine. Analysis of cerebral spinal fluid (CSF) obtained via lumbar puncture was positive for the Streptococcus antigen with cultures also growing Cryptococcus neoformans. Upon evaluation, patient was not found to be immunocompromised. This report works to highlight an atypical presentation of a cryptococcal CNS infection to raise awareness amongst clinicians hoping to prevent a delay in diagnosis of this disease given its high mortality.
On the Exact Solutions of Nonlinear Potential Yu–Toda–Sasa–Fukuyama Equation by Different Methods
Authors: Zhu Qinghao , Qi Jianming
Published: February 2022

In this article, the exact solutions to the potential Yu–Toda–Sasa–Fukuyama equation are successfully examined by the extended complex method and (G′/G)‐expansion method. Consequently, we find solutions for three models of Weierstrass elliptic functions, simply periodic functions, and rational function solutions. The obtained results will play an important role in understanding and studying potential Yu–Toda–Sasa–Fukuyama equation. It is observed that the extended complex method and (G′/G)‐expansion method are reliable and will be used extensively to seek for exact solutions of any other nonlinear partial differential equations (NPDEs).
Acupuncture Methods for Primary Trigeminal Neuralgia: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials
Authors: Yin Zihan , Wang Fumin , Sun Mingsheng , Zhao Ling , Liang Fanrong
Published: February 2022

Background. Primary trigeminal neuralgia (PTN) is a clinical refractory disorder characterized by excruciating pain that severely impacts the quality of life. Several studies have shown that acupuncture can improve PTN pain. However, the comparative efficacy and safety of acupuncture are unknown. Herein, a systematic review was conducted to compare the efficacy and safety of various acupuncture methods for PTN treatment. Methods. Relevant randomized controlled trials (RCTs) published up to 1 August 2021 were obtained from PubMed, Embase, Cochrane Central Register of Controlled Trials, Web of Science Core Collection, Chinese National Knowledge Infrastructure, Chinese Biomedical Literature Database, CQVIP Database, Wanfang Database, Allied and Alternative Medicine Database, and related registration platforms. Two authors independently selected the studies and obtained data. Cochrane Handbook was used to assess the methodological quality. We put the pain relief as the primary outcome and the response rate and adverse events as the secondary outcomes. Review Manager v5.3, ADDIS v1.16.8, and STATA v15.0 software were used for data analysis. The intraclass correlation coefficient was used to assess the consistency of the two investigators. Results. A total of 58 RCTs with 4,126 participants were obtained. The meta-analysis indicated that five acupuncture methods were superior to conventional medicine (carbamazepine) in pain reduction intensity and response rate. Meanwhile, electronic acupuncture plus manual acupuncture was the most effective therapy since it reduced pain intensity in 11 methods and improved the response rate in 10 interventions. Moreover, six interventions had acceptable adverse events, and none of the included studies reported severe adverse events. However, most pieces of evidence were ranked as critically low. Conclusion. These findings show that acupuncture methods can be effective and safe for PTN. Moreover, electronic acupuncture plus manual acupuncture maybe the best acupuncture treatment for PTN and should be administered to PTN patients. However, additional well-designed and high-quality RCTs should be conducted to verify the above findings in the future. The systematic review is registered with CRD42020221456.
Study of the Effect of Mineral Components on the Permeability Impairment Rate and Stress Sensitivity Factor of Shale
Authors: Wang Shuang , Wu Zhonghu , Chen Jun , Liu Hao , Wang Ruyue , Liu Jingshou
Published: February 2022

The mineral components play an indispensable role in shale reservoirs, and the study of their content and character are significant for the permeability impairment rate and stress sensitivity of shale reservoirs. In this study, the shale cores from the FC1 well of the Lower Cambrian Niutitang Formation in northern Guizhou were used to analyze the mineralogical composition of five samples using X-ray diffractometry and for measurement of permeability and porosity of samples by means of the FYKS-2 high-temperature overburden porosimeter with N2, and the samples were also subjected to uniaxial compression tests using the INSTRON 1346 electrohydraulic servo-controlled material testing machine (200T), thereby analyzing the effect of mineral components on the permeability impairment rate and stress sensitivity coefficient of shale. Results indicate that the permeability and porosity are negatively correlated with effective stress and clay mineral content, and positively correlated with detrital mineral content, whereas, the change of mineral composition is not obvious for porosity. Simultaneously, the permeability impairment rate and stress sensitivity factor decrease with growing quartz content and modulus of elasticity, and increase with rising clay mineral content. Additionally, the greater the brittle minerals content of shale, the more likely it is to undergo brittle damage and more crack extension during compression with predominantly elastic deformation, resulting in a lower stress sensitivity factor. Conversely, the higher is the stress sensitivity factor. The research results further deepen the understanding of mineral components on the permeability and mechanical properties of shale reservoirs.
The Use of Genetic Algorithm, Multikernel Learning, and Least-Squares Support Vector Machine for Evaluating Quality of Teaching
Authors: Yi Yingying , Zhang Hao , Karamti Hanen , Li Shasha , Chen Renmei , Yan Huan , Wang Chenguang
Published: February 2022

The educational data mining (EDM) methods are increasingly diversified. In this research, a hybrid method of multikernel learning (MKL), least-squares support vector machine (LSSVM), and genetic algorithm (GA) is employed to evaluate teaching quality through nine indicators; the reliability of our proposed method is evaluated by confidence interval and prediction interval. First, English teaching quality samples occurring from three age groups at Guizhou Normal University are collected. Next, an intelligent method MK-LSSVM is proposed. Finally, the test sets are regression by the proposed model, and regression results are evaluated by confidence interval, prediction interval, and several error calculation methods; we also develop an ablation experiment for our proposed model. The experiment indicates that the MKL-LSSVM-GA outperforms other benchmark methods at three age-group levels. Additionally, at all three age-group levels, the experiment indicates that three indicators are crucial for the evaluation of teaching quality. Therefore, the proposed model in this paper can evaluate the English teaching quality effectively.
To the Future: The Role of Exosome-Derived microRNAs as Markers, Mediators, and Therapies for Endothelial Dysfunction in Type 2 Diabetes Mellitus
Authors: Fluitt Maurice B. , Mohit Neal , Gambhir Kanwal K. , Nunlee-Bland Gail
Published: February 2022

The prevalence of diabetes mellitus (DM) is increasing at a staggering rate around the world. In the United States, more than 30.3 million Americans have DM. Type 2 diabetes mellitus (T2DM) accounts for 91.2% of diabetic cases and disproportionately affects African Americans and Hispanics. T2DM is a major risk factor for cardiovascular disease (CVD) and is the leading cause of morbidity and mortality among diabetic patients. While significant advances in T2DM treatment have been made, intensive glucose control has failed to reduce the development of macro and microvascular related deaths in this group. This highlights the need to further elucidate the underlying molecular mechanisms contributing to CVD in the setting of T2DM. Endothelial dysfunction (ED) plays an important role in the development of diabetes-induced vascular complications, including CVD and diabetic nephropathy (DN). Thus, the endothelium provides a lucrative means to investigate the molecular events involved in the development of vascular complications associated with T2DM. microRNAs (miRNA) participate in numerous cellular responses, including mediating messages in vascular homeostasis. Exosomes are small extracellular vesicles (40-160 nanometers) that are abundant in circulation and can deliver various molecules, including miRNAs, from donor to recipient cells to facilitate cell-to-cell communication. Endothelial cells are in constant contact with exosomes (and exosomal content) that can induce a functional response. This review discusses the modulatory role of exosomal miRNAs and proteins in diabetes-induced endothelial dysfunction, highlighting the significance of miRNAs as markers, mediators, and potential therapeutic interventions to ameliorate ED in this patient group.
Land Cover Change and Its Impact in Crop Yield: A Case Study from Western Nepal
Authors: Bhandari Ajay , Joshi Rajeev , Thapa Mahendra Singh , Sharma Ram Prasad , Rauniyar Sumit Kumar
Published: February 2022

This study was conducted in Tanahun district of Gandaki Province, Nepal, to analyze the land cover change over two decades, the migration effect in land cover, and the impact caused in crop production by Rhesus macaque. Landsat TM/ETM+ for land use of 2000 and 2010 extracted by ICIMOD and Landsat 8 OLI/TIRS satellite images for land cover 2019 were downloaded from the USGS website. A purposive sample for household survey was carried out based on crops damaged by the monkey. Two hundred and fifty households were taken as samples. The Landsat images were analyzed by ArcGIS, and the social data were analyzed using SPSS and MS Excel. Land cover change data revealed increment of forest cover from 36.57% to 40.91% and drastic decrease in agriculture crops from 57.52% to 43.78% in the period of 20 years. The accuracy of the data showed overall classification accuracy of 86.11%, 81.08%, and 75% with overall kappa statistics 0.83, 0.77, and 0.74, respectively. The migration effect in the land cover was related to remittance and migrated members and found a significant positive relationship. Analyzing the trend of production with an increase in the forest cover, 21% decrease in paddy, 5% decrease in maize, and 26% decrease in millet were found as compared to the production in 2000. The econometric model concluded that the quantity of crop damage was negatively significant in relation to distance from forest and distance from water body while positively significant to distance from settlements and distance from owner’s home. The quantity of crop damage was estimated 113.89 kg per household, and the cost was 78.82 USD. This study recommends active forest management; regular thinning, and weeding. Remittance generated should be invested in the agriculture field by the households. Damage relief should be made available for the damage cost by Rhesus macaque.
Interpolative Prešić Type Contractions and Related Results
Authors: Alansari Monairah , Ali Muhammad Usman
Published: February 2022

In this article, we will extend the notion of interpolative Kannan contraction by introducing the notions of interpolative Prešić type contractions and interpolative Prešić type proximal contractions for mappings defined on product spaces. Through these notions, we will derive some results to ensure the existence of fixed points and best proximity points for such mappings.
On the Partial Sums of the q‐Generalized Dini Function
Authors: El-Qadeem Alaa H. , Mamon Mohamed A. , Elshazly Ibrahim S.
Published: February 2022

Our objective in this paper is to introduce a q‐analog of the generalized Dini function. Also, we investigate the lower bound for the ratio of the q‐generalized Dini function to its sequences of partial sums.
An Analysis of Computed Tomography Imaging Features and Predictive Factors for Postoperative Recurrence and Metastasis of Abdominal Paragangliomas
Authors: Dai Bailing , He Jie , Zhu Xiandi , Xie Zongyu , Zhang Cui , Zhou Xiaoli , Yang Zhao , Wang Jian
Published: February 2022

Background and Objectives. Recurrence and metastasis are the most important factors influencing the survival rate of patients with paragangliomas (PGLs). Accurate preoperative prediction of the risk factors and developing a reasonable therapy strategy can reduce the recurrence rate. Computed tomography (CT) is regarded as the preferred imaging modality for the initial evaluation of PGLs. However, only a few studies have investigated the relationship between CT features and the invasiveness of PGLs. Therefore, we investigated the prognostic importance of CT features for PGLs. Methods. We studied 51 abdominal PGL patients at the First Affiliated Hospital of Bengbu Medical College, Tongde Hospital, and Sir Run Shaw Hospital, Hangzhou, Zhejiang Province, China, from June 2009 to May 2019. Thereafter, the clinical research data, tumor biomarkers, and CT features were compared between the aggressive PGLs and the nonaggressive PGLs using independent‐samples t‐tests and chi‐square tests. Results. Of the 51 cases, 43 were benign and 8 had malignant tendencies. Postoperative recurrence and metastasis were more likely to occur when the tumor diameter was >8 cm or/and the enhancement degree was not obvious. Clinical symptoms, tumor markers, sex, age, and CT image characteristics including morphology, presence of cystic degeneration, “pointed peach” sign, calcification, hemorrhage, enlarged lymph nodes, and peritumor and intratumor blood vessels were not significantly different between the two groups (p > 0.05). Conclusion. Our findings suggest that CT features, including size >8 cm and enhancement degree, could provide important evidence to assess risk factors for aggressive PGLs.
Identification of Four Metabolic Subtypes of Glioma Based on Glycolysis-Cholesterol Synthesis Genes
Authors: Zhang Jinsen , Xiao Xing , Guo Qinglong , Wei Zixuan , Hua Wei
Published: February 2022

Based on alterations in gene expression associated with the production of glycolysis and cholesterol, this research classified glioma into prognostic metabolic subgroups. In this study, data from the CGGA325 and The Cancer Genome Atlas (TCGA) datasets were utilized to extract single nucleotide variants (SNVs), RNA-seq expression data, copy number variation data, short insertions and deletions (InDel) mutation data, and clinical follow-up information from glioma patients. Glioma metabolic subtypes were classified using the ConsensusClusterPlus algorithm. This study determined four metabolic subgroups (glycolytic, cholesterogenic, quiescent, and mixed). Cholesterogenic patients had a higher survival chance. Genome-wide investigation revealed that inappropriate amplification of MYC and TERT was associated with improper cholesterol anabolic metabolism. In glioma metabolic subtypes, the mRNA levels of mitochondrial pyruvate carriers 1 and 2 (MPC1/2) presented deletion and amplification, respectively. Differentially upregulated genes in the glycolysis group were related to pathways, including IL-17, HIF-1, and TNF signaling pathways and carbon metabolism. Downregulated genes in the glycolysis group were enriched in terpenoid backbone biosynthesis, nitrogen metabolism, butanoate metabolism, and fatty acid metabolism pathway. Cox analysis of univariate and multivariate survival showed that risks of glycolysis subtypes were significantly higher than other subtypes. Those results were validated in the CGGA325 dataset. The current findings greatly contribute to a comprehensive understanding of glioma and personalized treatment.
The Tempo of Mammalian Embryogenesis: Variation in the Pace of Brain and Body Development
Authors: Halley Andrew C.
Published: February 2022

Why do some species develop rapidly, while others develop slowly? Mammals are highly variable in the pace of growth and development over every stage of ontogeny, and this basic variable – the pace of ontogeny – is strongly associated with a wide range of phenotypes in adults, including allometric patterns of brain and body size, as well as the pace of neurodevelopment. This analysis describes variation in the pace of embryonic development in eutherian mammals, drawing on a collected dataset of embryogenesis in fifteen species representing rodents, carnivores, ungulates, and primates. Mammals vary in the pace of every stage of embryogenesis, including stages of early zygote differentiation, blastulation and implantation, gastrulation, neurulation, somitogenesis, and later stages of basic limb, facial, and brain development. This comparative review focuses on the general variation of rapid vs. slow mammalian embryogenesis, with a focus on the pace of somite formation, brain vs. somatic development, and how embryonic pacing predicts later features of ontogeny.
Direitos Humanos, Esporte e Educação Física: desafos e perspectivas
Authors: Ferreira Lúcio Fernandes , Barros João Luiz da Costa , Bruzi Alessandro Teodoro , Freudenheim Andrea Michele
Published: February 2022

Apresentamos os desafios e perspectivas envolvendo Direitos Humanos, Esporte e a Educação Física como agentes promotores da dignidade da pessoa humana. Valemo-nos dos principais documentos basilares do tema em questão e apontamos a necessidade do fortalecimento da educação em Direitos Humanos para viabilizar a construção de saberes capazes de desenvolver uma cultura de respeito aos DH e legitimar a luta pelos direitos sociais. Chamamos a atenção para o atendimento às necessidades de diferentes populações, especialmente, às que apresentam o Transtorno do Desenvolvimento da Coordenação com destaque para as questões envolvendo sua etiologia, os instrumentos de identificação e diagnóstico e a intervenção. Nosso entendimento é de que o Esporte e a Educação Física Escolar figurem como eixos articuladores dos DH, promovendo uma relação dialógica na construção de saberes plurais, heterogêneos e experenciais ao longo da existência humana.
Direitos humanos e formação profssional no ensino superior
Authors: Daxenberger Ana Cristina Silva
Published: February 2022

Os estudos no campo de direitos humanos têm se consolidado nas últimas décadas, principalmente, após a proclamação da Constituição Federal, de 1988, que reconhece o indivíduo como sujeito de direitos. Considerando isso, o presente artigo tem como objetivo apresentar quais são os pressupostos teórico-práticos que estão presente na formação de graduandos dos cursos do Centro de Ciências Agrárias da Universidade Federal da Paraíba em relação à formação cidadã em direitos humanos e apresentar como isso se desenvolve. Pensar em educação em direitos humanos se faz necessário na formação profissional, no ensino superior, considerando que todos os profissionais assumem responsabilidades técnicas e sociais ao exercerem sua atuação. Conhecer a realidade social é diferencial na formação profissional e pode favorecer discussões e proposições práticas para compreender a realidade e modifcá-la.
Comportamento da temperatura da pele durante uma meia maratona em ambiente quente sob radiação solar
Authors: Rodrigues Júnior Jefferson Fernando Coelho , Almeida Isabel Cristina de Oliveira , Martins Vicenilma de Andrade , Cruz Francisco Railson de Oliveira , Reis Junior Jodimar Ribeiro dos , Cabido Christian Emmanuel Torres , Oliveira Junior Mario Norberto Sevilio de
Published: February 2022

O objetivo é avaliar a temperatura da pele (TP) em diferentes regiões durante uma meia-maratona em ambiente quente sob radiação solar. O estudo foi realizado em 10 corredores com idades de 33,40±10,04 anos, peso de 66,40±9,15 kg, estatura de 1,71±0,06 m, e VO2pico de 58,57±5,47ml.kg¹.min¹. A corrida de 21km foi realizada em um trajeto pré-determinado, com temperatura ambiente de 27,96±1,70ºC, umidade relativa do ar 76,88±7,49% e Índice de Temperatura de Globo e Bulbo Úmido de 25,80±1,18ºC. Medidas de TP foram mensuradas antes, a cada 3km e ao término da corrida. Para todos os testes o nível foi de P<0,05, para as comparações entre os momentos utilizou-se o teste ANOVA one-way, com post hoc de Tukey. O tempo médio de corrida e ritmo foram de 101:00±9:52 minutos e 4:48±00:16 min•km-1, respectivamente. Observou-se que a temperatura de todas as regiões da pele foi reduzida em 1,35±1,75C° ao longo da corrida, a temperatura do topo da cabeça foi a menor 31,2°C±2,11°C e a da testa foi a maior 33,7±1,35°C. Em nosso estudo, a TP diminuiu, entretanto, a magnitude da redução é diferente, devido a particularidade de cada região avaliada, seja pelo fluxo sanguíneo, número de glândulas sudoríparas, densidade das glândulas ou pela exposição à radiação.
O consumidor esportivo e o Novo Basquete Brasil: análise do perfil do torcedor nas finais Bauru x Paulistano em 2017
Authors: Padeiro Carlos Henrique de Souza , Rocco Junior Ary José , Vanucci Luis Henrique Torquato
Published: February 2022

O objetivo do estudo é analisar as conexões entre o basquete e o perfil de torcedores que compareceram aos dois últimos jogos das finais da nona edição do Novo Basquete Brasil (NBB), em 2017. A pesquisa tem natureza qualitativa, e o percurso metodológico valeu-se da aplicação aleatória de um questionário com 39 perguntas junto aos torcedores presentes nos ginásios, ou no seu entorno, momentos antes dos jogos, disputados em junho de 2017, nas cidades de São Paulo e Araraquara. A partir da análise de 91 questionários e da observação das ações de patrocínio, foi realizada uma entrevista semiestruturada com o Gerente de Comunicação da Liga Nacional de Basquete (LNB). Os resultados indicam a predominância de um público masculino, jovem e de alto poder aquisitivo nos dois jogos (57% dos respondentes têm renda familiar mensal acima de R$ 4,5 mil). Esses torcedores apresentam um envolvimento afetivo com o basquete e com os times, porém não têm uma relação formal ou monetária com as equipes. A comunicação via mídias sociais atinge boa parcela desse público, que aprova ações de entretenimento durante o evento esportivo. Portanto, há um potencial para estreitar o relacionamento com os torcedores. O trabalho desenvolvido há dez anos pela LNB tem gerado parcerias com empresas e grandes grupos de comunicação, além da adoção de práticas bem-sucedidas no exterior na gestão esportiva. Em 2014, a Liga anunciou uma parceria inovadora e de longo prazo com a National Basketball Association (NBA). Há obstáculos a serem superados, principalmente na administração dos clubes, e este artigo espera contribuir para a melhoria do processo.
A (in)visibilidade dos Direitos Humanos nos cursos de licenciatura em Educação Física de universidades federais brasileiras
Authors: Palmeira Lana Lisiêr de Lima , Cordeiro Carla Priscilla Barbosa Santos , Prado Antonio Gottschlisch do , Prado Edna Cristina do
Published: February 2022

O presente artigo tem com objeto de investigação a formação de licenciados em Educação Física e visa compreender se os elementos que dão corpo à Educação em Direitos Humanos estão inseridos na referida formação e, em estando, se essa presença se dá de forma satisfatória no sentido de não apenas formar pessoas aptas tão somente a saberes e competências técnicas, mas se busca forjá-las em sua integralidade, tornando-as sujeitos de direitos na acepção mais ampla do vocábulo. A partir de uma abordagem qualitativa à luz da Análise de Conteúdo, discute conceitos fundantes da Educação em Direitos Humanos e do preconizado nas Diretrizes Curriculares Nacionais que regulam os cursos de Educação Física para empreender a análise dos projetos político-pedagógicos e dos currículos dos cursos de licenciatura em Educação Física, mais antigos, ofertados nas universidades federais brasileiras. Os resultados revelam a subalternização dos elementos humanísticos em comparação aos conteúdos técnicos e a conclusão do estudo reforça a necessidade de mais pesquisas acerca da temática em tela e a convicção de que, de alguma forma, a reﬂexão apresentada pode contribuir para as searas que retroalimentam o humanismo na ambivalência universitária.
Educación internacional: las nuevas tecnologias y la gestión creativa como motor de cambios
Authors: Hidalgo Andrea , Herrera Elizabeth Colorado
Published: February 2022

Este texto sistematiza experiências educacionais que geram oportunidades de internacionalização para alunos do Ensino Superior do Brasil e da Argentina. Propostas da Unesco sobre competências essenciais no século 21 reconhecem linguagens e novas tecnologias nos processos de troca. O trabalho relata experiências, atravessadas pela gestão criativa, realizadas antes e durante a pandemia.

PALAVRAS-CHAVE: Educação Superior. Internacionalização. Línguas.
José de Moura Leite Neto – reflexão sobre o jornalismo de ciência e o papel da rede brasileira de jornalistas e comunicadores de ciência
Authors: Tôzo Carla de Oliveira
Published: February 2022

José de Moura Leite Neto é jornalista, doutor em Oncologia pela A.C. Camargo Cancer Center e um dos fundadores e atual presidente da Rede Brasileira de Jornalistas e Comunicadores de Ciência. Em entrevista realizada no dia 12 de novembro de 2021, ele falou sobre o papel da RedeComCiência e refletiu sobre o conceito de jornalismo científico, a formação do jornalista especializado em ciências e a produção desse tipo de jornalismo pelas universidades.
Educação para uma leitura midiática feminista
Authors: Rodella Ester Alkimim Zanco
Published: February 2022

Todos os dias os meios de comunicação divulgam notícias referentes a feminicídios ou outros tipos de violências contra as mulheres. Este artigo pretende analisar o fato de que, até mesmo notícias que envolvem mulheres e não são sobre essas violências diretas e culturais e sim sobre abordagens do mundo feminino (como Dia Internacional da Mulher, por exemplo) podem ter uma carga de violência em mensagens subliminares. E como as mulheres recebem essas notícias? Será que elas se sentem representadas pelas mesmas? Selecionamos algumas imagens veiculadas pelo MBL (Movimento Brasil Livre) em sua página do Facebook,  no Dia Internacional da Mulher de 2018 e 2019, e as mostramos a integrantes do coletivo feminista Rede Panapanã de Mulheres do Noroeste Paulista, de Votuporanga, como forma de ter um feedback dessa leitura e de propor um programa de alfabetização midiática  junto a esse grupo de mulheres.