bluuebunny/crossref_metadata_2025 huggingface dataset:
Pathomorphological analysis of budding in colorectal carcinomas
Authors: Shponka I. S. , Poslavska O. V. , Kharkhalis I. K. , Shynkarenko T. V.
Published: October 2023

Morbidity and mortality from colorectal cancer (CRC) remains a current problem of modern oncology. Intensive budding is an important prognostic factor for a worse clinical course of CRC and may influence clinical decision-making regarding the use of extended interventions in pT1 and stage II, according to the conclusion of the 2016 International Consensus Conference on Tumor Budding.
The aim of the work is to evaluate the prognostic significance of budding depending on the clinical and morphological characteristics of colorectal carcinomas.
Materials and methods. The article deals with clinical and anatomical material of 31 patients with CRC (14 women and 17 men) who were treated in the 2nd surgical department of the SE “Dnipropetrovsk Regional Clinical Hospital” in the period from 2019 to 2021. The age of the patients varied of 27–84 years old (average age – 62.3 ± 14.8 years old). A histological examination of CRC samples was carried out with an assessment of “hot areas” of the invasive front and an immunohistochemical examination with РАН CK АЕ 1/3, Ki-67, MUC2, caspase-3, β-catenin to calculate the number of tumor cell clusters.
Results. In one third of the number of samples, differences were determined not only in the number of clusters, but also in the budding category when stained by routine and immunohistochemical methods. Peritumoral budding of the invasive front with category Bd3 was always accompanied by intratumoral budding of varying degrees of intensity. The analysis of the distribution of gradations of budding of colorectal carcinomas by gender, age, location, histological degree of differentiation, and the presence of metastases did not show a statistically significant difference (p > 0.05), which may indicate the independence of this factor on the prognosis of patient survival. The intensity of budding of colorectal carcinomas depending on the expression of markers Ki-67, caspase-3 and β-catenin did not show a significant difference in subgroups (p > 0.05) but showed tendencies to increase the number of budding with an increase in the proliferation index and a decrease in the activity of the proapoptotic enzyme caspase-3.
Conclusions. If the number of buds on the border of categories Bd1 and Bd2, or Bd2 and Bd3, determined by the standardized method of H & E staining is doubtful, the degree of budding may be underestimated in comparison with staining by the immunohistochemical method, due to the exclusion of falsely interpreted morphological objects as tumor clusters; the most reliable immunohistochemical marker for contrast separation of buds is a cocktail of cytokeratins.
Modulation of the tissue composition of regenerative neuroma by dexamethasone and granulocyte colony-stimulating factor
Authors: Grabovyi O. M. , Nevmerzhytska N. M. , Alyokhin A. B. , Kostynskyi H. B. , Rytikova N. V.
Published: October 2023

Aim. To evaluate the change of the content of mesenchymal (vimentin-positive) and reparative Schwann (GFAP-positive) cells in the regenerative neuroma of the rat sciatic nerve, taking into account the activity of local homeostasis regulation (CD73 expression) under the influence of dexamethasone (Dex) and granulocyte colony-stimulating factor (GCSF).
Materials and methods. Vimentin-, GFAP-, and CD73-positive cells were detected immunohistochemically in the regenerative neuroma of 168 male Wistar rats, and their presence was quantified using statistical methods.
Results. The regenerative neuroma of the sciatic nerve is characterized by a stereotypical cellular composition kinetics. Dexamethasone, during the initial stage of neuroma formation (1–7 days), led to a reduction in inflammatory infiltration and accumulation of vimentin+ mesenchymal cells. It significantly accelerated the accumulation of neural GFAP+ reparative Schwann cells and suppressed the expression of CD73. The granulocyte colony-stimulating factor (1–3 days) in the regenerative neuroma resulted in a slight reduction in inflammatory infiltration and an increase in the number of blood vessels penetrating into it. Under these conditions, the speed and quantity of vimentin+ cell accumulation and CD73 expression noticeably increased, as well as the speed of GFAP+ cell accumulation. The deviations in the expression of vimentin, GFAP, and CD73 in the neuroma under the administration of the mentioned substances gradually decreased and, after 8 weeks of the experiment, did not differ significantly from the control. When combined, dexamethasone and granulocyte colony-stimulating factor potentiated each other’s effects and, in addition, led to long-term maintenance of high CD73 expression. At the same time, the most pronounced approximation of the structure of the newly formed part of the nerve to the structure of the intact nerve trunk was observed.
Conclusions. The simultaneous action of Dex and GCSF during the initial stages of regenerative neuroma formation, in contrast to their individual actions, not only alters the dynamics of mesenchymal and neural cell accumulation but also modifies the newly formed part of the nerve, bringing its structure closer to the intact state. This phenomenon is accompanied by increased reactivity of neurolemocytes during the axial cylinder germination stage of neuroma regeneration.
Obrazy stalinizmu w twardym jądrze i na peryferiach. Kłopoty ze Sceną Faktu TVP (2006–2010)
Authors: Szpulak Andrzej
Published: October 2023

The text refers to the part of the performances of TVP’s Fact Stage (2006–2010), devoted to the Stalinist period, as well as to its journalistic and scholarly reception. In no small part, it is a polemic with the position and reasoning expressed in Mariusz Mazur’s article TV Theater: Fact Stage – a specific vision of history. On such historical politics polemically. The author points to the need to interpret the phenomenon of Fact Stage as it really was, to understand its genesis, social conditions and cultural context. However, he rejects the method of contrasting the works in question with the abstract and normative postulates formulated by Mazur. Finally, the article points to the religious (morality play and passion play) sources of the conception of Fact Stage performances.
Non-fiction cinema of independent Ukraine
Authors: Marchenko Serhiy
Published: October 2023

The article covers the thematic and genre diversity of non-fiction cinema in Ukraine, which following the country’s regaining its independence in 1991, launched a reflection on previously hushed-up topics that were prohibited or covered in a tendentious manner in the Soviet period. The number of films and TV series grew, and the ideological gap between film artists and political elites (partly pro-Russian) resulted in their mass distribution being prevented. This was especially evident in the several-year delay and limits placed on showing the long-awaited series “Unknown Ukraine. Essays of Our History” (1993, NKU-Kyivnaukfilm, 144 films). Quantitative and qualitative changes in this type of cinema over the last three decades are analyzed in this article, presenting periods of its ups and downs, which are synchronized with changes in political processes in Ukraine. It shows how after the mass protests of the Euromaidan Revolution in 2014 and the beginning of the Russian-Ukrainian war, the number of such films increased significantly, providing a considerable informative and educational impact.
The effect of ratios upon improving patient-based real-time quality control (PBRTQC) performance
Authors: Li Yuanyuan , Chen Xiaoling , Zhao Ying
Published: October 2023

Objectives

Large biological variation hinders application of patient-based real-time quality control (PBRTQC). The effect of analyte ratios on the ability of PBRTQC to improve error detection was investigated.

Methods

Four single analyte-ratio pairs (alanine aminotransferase [ALT] vs. ALT to aspartate aminotransferase ratio [RALT]; creatinine [Cr] vs. Cr to cystatin C ratio [RCr]; lactate dehydrogenase [LDH] vs. LDH to hydroxybutyrate dehydrogenase ratio [RLDH]; total bilirubin [TB] vs. TB to direct bilirubin ratio [RTB]) were chosen for comparison. Various procedures, including four conventional algorithms (moving average [MA], moving median [MM], exponentially weighted moving average [EWMA] and moving standard deviation [MSD]) were assessed. A new algorithm that monitors the number of defect reports per analytical run (NDR) was also evaluated.

Results

When a single analyte and calculated ratio used the same PBRTQC parameters, fewer samples were needed to detect systematic errors (SE) by taking ratios (p<0.05). Application of ratios in MA, MM and EWMA significantly enhanced their ability to detect SE. The influence of ratio on random error (RE) detection depended upon the analytes and PBRTQC parameters, as consistent advantage was not demonstrated. The NDR method performed well when appropriate parameters were used, but was only effective for unilateral SE. Rearrangement of sample order led to a significant deterioration of conventional algorithms’ performance, while NDR remained almost unaffected.

Conclusions

For analytes with large variation and poor PBRTQC performance, using ratios as PBRTQC indexes may significantly improve performance and achieve better anti-interference ability, providing a new class of monitoring indicators for PBRTQC.
Science and Survival: Exploring the Papers of Georg and Max Bredig
Authors: Shea Patrick H.
Published: October 2023

Following the death of his parents, George Bredig inherited a large steamer trunk inconspicuously tucked away in the basement of his boyhood home in Oak Ridge, Tennessee. The trunk was old, and upon opening it, a strong musty smell emerged from within. As he reviewed the contents of the trunk, he discovered an assortment of unpublished letters, original photographs, rare pamphlets and small scientific artifacts. His father Max and grandfather Georg were both gifted physical chemists and it did not take long for George to realize that these papers documented their scientific careers in the years preceding their flight from Nazi Germany.
A novel travel route planning method based on an ant colony optimization algorithm
Authors: He Shan
Published: October 2023

As people’s living standards improve, tourism has become an important way for people to spend their time on leisure and entertainment. The growing number of tourists in recent years has given rise to the creation of tourism-related ancillary services. Travelers need to choose a travel route that suits their needs and expectations and do it in a way that does not cause a waste of time, whether it is an emerging self-driving tour or a traditional tour group. Therefore, the optimization of tourist routes is of great significance to the majority of tourists. Given the planning requirements of tourist attractions in the post-epidemic era, an ant colony-based optimization algorithm is proposed to resolve the planning problem of optimal tourist routes. An optimized pheromone update strategy is also proposed based on the basic ant colony optimization algorithm. The optimized ant colony algorithm tries to balance two conflicting concepts, namely, flows into tourist attractions and the carrying capacity of destinations. To analyze the performance of the proposed optimization algorithm, the effects of different optimization algorithms on the route planning of tourist attractions were compared in the experiment, and the acceleration ratio of the optimized ant colony algorithm was tested using the graphics processing unit parallel computing program. The results show that the proposed algorithm provides certain advantages and has certain potential in parallel computing. To sum up, this study provides a better scientific basis for optimal tourist route planning and has a good reference value.
The impact of zirconia nanoparticles on the mechanical characteristics of 7075 aluminum alloy
Authors: Al Zubaidi Faten N. , Asaad Lamyaa Mahdi , Alshalal Iqbal , Rasheed Mohammed
Published: October 2023

In numerous engineering applications, metal matrix composites strengthened by ceramic particles have played an important role. For this purpose, an aluminum (Al 7075) nanocomposite has been fabricated, and nano-zirconium oxide of particle size 40 nm (0, 0.8, 1.6, and 2.4) wt% reinforced Al 7075 alloy was produced using a stir-casting process. The effect of ZrO2 NPs loading on mechanical properties along with the detailed characterization were demonstrated. The performance of Al with ZrO2 nanocomposite was investigated by Vickers hardness tester, scanning electron microscopy, energy-dispersive X-ray, compression test, Lee’s disc, and Shore D instruments were utilized to determine the hardness, structural morphology, composition of the elements, Young’s modulus, thermal conductivity, and roughness values of the samples, respectively. The hardness (120.3–177) HV, compression strength (624.2–878.6) MPa, yield modulus (38–70) MPa, surface roughness (0.876–0.606) µm, thermal conductivity (2.0–2.39) W/m2 °C improved by increasing the wt% of ZrO2 NP reinforcement particles. The implication of these findings shows that 5 wt% nano-ZrO2-reinforced Al 7075 composites yielded better performance than pure Al 7075 alloy. To sum up, this investigation demonstrated that the ZrO2 reinforcement enhanced the mechanical properties of Al 7075.
The crystal structure of (E)-4-fluoro-N′-(1-(4-hydroxyphenyl)propylidene)benzohydrazide, C16H15FN2O2
Authors: Wen Juanjuan , Liu Langlang , Tang Wenqiang , Liu Bin
Published: October 2023

C16H15FN2O2, orthorhombic, P212121 (no. 19), a = 7.2516(6) Å, b = 11.3780(9) Å, c = 17.1177(13) Å, V = 1412.36(19) Å3, Z = 4, R

gt
(F) = 0.0498, wR

ref
(F
2) = 0.1201, T = 293 K.
Senescent Schwann cells induced by aging and chronic denervation impair axonal regeneration following peripheral nerve injury
Authors: Fuentes‐Flores Andrés , Geronimo‐Olvera Cristian , Girardi Karina , Necuñir‐Ibarra David , Patel Sandip Kumar , Bons Joanna , Wright Megan C , Geschwind Daniel , Hoke Ahmet , Gomez‐Sanchez Jose A , Schilling Birgit , Rebolledo Daniela L , Campisi Judith , Court Felipe A
Published: October 2023

Following peripheral nerve injury, successful axonal growth and functional recovery require Schwann cell (SC) reprogramming into a reparative phenotype, a process dependent upon c‐Jun transcription factor activation. Unfortunately, axonal regeneration is greatly impaired in aged organisms and following chronic denervation, which can lead to poor clinical outcomes. While diminished c‐Jun expression in SCs has been associated with regenerative failure, it is unclear whether the inability to maintain a repair state is associated with the transition into an axonal growth inhibition phenotype. We here find that reparative SCs transition into a senescent phenotype, characterized by diminished c‐Jun expression and secretion of inhibitory factors for axonal regeneration in aging and chronic denervation. In both conditions, the elimination of senescent SCs by systemic senolytic drug treatment or genetic targeting improved nerve regeneration and functional recovery, increased c‐Jun expression and decreased nerve inflammation. This work provides the first characterization of senescent SCs and their influence on axonal regeneration in aging and chronic denervation, opening new avenues for enhancing regeneration and functional recovery after peripheral nerve injuries.
The Influence of Work Spirit and Work Discipline on Employee Work Productivity With Job Satisfaction as Intervening Variables in DPRD Secretariat Labuhanbatu District
Authors:   Universitas Prima Indonesia, Faris Salman , Utomo Bayu ,   Universitas Prima Indonesia, Syaifuddin Syaifuddin ,   Universitas Prima Indonesia, Sutanto Alex Tribuana ,   Universitas Prima Indonesia
Published: October 2023

Study aims to determine whether work enthusiasm and work discipline affect employee work productivity through job satisfaction as an intervening variable at the Secretariat of the DPRD Labuhanbatu Regency. The study was conducted on 53 employees using a saturated sampling technique. The data collection technique used was primary data in the form of questionnaires and secondary data obtained through documentation studies. The data analysis technique used quantitative data which was processed using the SPSS version 25 program, namely the t test, Sobel test and path analysis. For future researchers, this research should be developed more broadly to obtain stronger empirical results by adding other variables that affect employee work productivity.
The Impact of the Modern Global Environment on the Formation of the Ukrainian Economic Security
Authors:   Mariupol State University, Fedorov Eduard
Published: October 2023

The article examines the modern global processes that create challenges and threats to the international security environment. Global trends that pose threats to the security systems of national economies are identified and classified. Modern global challenges of a new format (COVID-19 pandemic, digitalisation, etc.) are highlighted. The interrelation between the level of globalisation of Ukraine and the level of its economic security is investigated. The scale of financial globalisation of the Ukrainian economy in the context of the overall level of financial globalisation of the world economy is determined. It is substantiated that during the years of independence, the impact of global environment factors on the Ukrainian economic security has increased, the most powerful of which are the global financial crisis, the COVID-19 pandemic and the full-scale war. A comparative analysis of changes in the main parameters of the economic environment is carried out, the impact of the global financial crisis, pandemic and war on the economic security of Ukraine is determined.
Ways to Increase the Competitiveness of Banking Institutions
Authors:   Odesа Polytechnic National University, Filippov Volodymyr , Korsikova Oleksandra ,   Odesа Polytechnic National University
Published: October 2023

Banking is one of the most competitive industries, which is crucial for the financial stability of the economy. The ability of financial institutions to compete depends on a variety of elements, including management efficiency, resourcefulness and market adaptability. Unlike other countries of the world, the competitiveness of banking institutions on the Ukrainian market is still quite low. This is caused by many factors, first of all, the invasion of Ukraine by an aggressor country, which led to an increase in the level of risks, a slowdown in the development of financial culture, and a lack of high-tech banking solutions. Despite these challenges, the banking system of Ukraine has the potential to become more competitive and reach the international level. The use of the latest standards and technologies, active participation in integration procedures, increasing public trust in the financial system and attracting investments – all this can contribute to the competitiveness of Ukrainian banks. This article discusses the ways of increasing the competitiveness of banking institutions.
Current Situation of Online Education and Challenges Facing Educational Institutions in Ukraine During Martial Law
Authors:   Odesа Polytechnic National University, Filippov Volodymyr , Emerson Ann ,   University of Portsmouth, Zaichenko Kateryna ,   Odesа Polytechnic National University, Yangulov Elvin ,   Odesа Polytechnic National University
Published: October 2023

In Ukraine, during a state of war, many children are learning online instead of attending physical schools. Learning is conducted remotely from home or other places where conditions allow. The state has also faced a range of problems that need to be addressed promptly and without experience in dealing with similar situations. Ukraine has faced problems with distance learning since the beginning of the pandemic, and with the increase of Russian aggression, the situation has become even more challenging, despite the state's efforts to improve it. However, Ukraine has been able to follow the same path that European countries took several decades ago in a very short period of time. Studying and analyzing the current situation will allow recommendations to be made for solving similar problems not only in Ukraine but also in other countries where armed conflicts will interfere with the learning process. This article is an interim outcome of the UUT21 project (Research Project No. 1877-01/21) "Online Learning during times of conflict and the welfare of children and teachers".
Characteristics of cardiac arrhythmia and heart rate variability in Chinese patients with primary aldosteronism
Authors: Wan Shuang , Zheng Chengcheng , Chen Tao , Tan Lu , Tang Jia , Tian Haoming , Ren Yan
Published: October 2023

We applied 24-h Holter monitoring to analyze the characteristics of arrhythmias and heart rate variability in Chinese patients with primary aldosteronism (PA) and compared them with age-, sex-, and blood pressure-matched primary hypertension (PH) patients. A total of 216 PA patients and 261 PH patients were enrolled. The nonstudy data were balanced using propensity score matching (PSM), and the risk variables for developing arrhythmias were then analyzed using logistic regression analysis. Before PSM, the proportion of PA patients with combined atrial premature beats and prolonged QT interval was higher than the corresponding proportion in the PH group. After PSM, the PA group had a larger percentage of transient atrial tachycardia and frequent atrial premature beats, and it had higher heart rate variability metrics. The proportion of unilateral PA combined with multiple ventricular premature beats was higher than that of bilateral PA. Older age, grade 3 hypertension, and hypokalemia were independent risk factors for the emergence of arrhythmias in PA patients. PA patients suffer from a greater prevalence of arrhythmias than well-matched PH patients.
Adhesive bonding performance of thermally modified yellow poplar
Authors: Masoumi Abasali , Balma Francisco Xavier Zambrano , Bond Brian H.
Published: October 2023

Thermal modification of wood changes its chemical, physical, and structural properties, which may affect adhesive bondline quality and bonding performance. This research compared the effect of thermal modification on the adhesive bonding performance of poplar (Liriodendron tulipifera) wood. Samples were prepared from thermally modified and unmodified yellow poplar using one-component polyurethane (PUR) and polyvinyl acetate (PVA), as they are adhesives used in wood products. Microscopic properties of the bondlines were investigated to understand shear performance and durability. Adhesive line thickness, penetration, shear strength, and moisture durability were measured, and failure modes were recorded. Thermal modification negatively affected the wood and adhesive interaction by reducing penetration (31.2% in PUR and 29% in PVA), therefore creating a thicker adhesive line (70% in PUR and 2% in PVA) and consequently causing a significant reduction in the shear strength of both adhesive types (27% in PUR and 36% in PVA) compared with non-modified specimens. The PUR adhesive had higher shear strength than PVA by 2.7% in non-modified and 14% in thermally modified wood.
Switching to the Ukrainian language as a factor of hystorical memory restoration (on the example of Volodymyr Rafieienko’s novel “Mondegreen”)
Authors:   Institute of the Ukrainian Language of the National Academy of Sciences of Ukraine, Masenko Larysa
Published: October 2023

The article focuses on the language and artistic senses of the novel “Mondegreen. Songs about Deaths and Love” by Volodymyr Rafieienko. The author was born in Donetsk; by 2014, he used to write his books in the Russian language, had them published in Moscow publishing houses, and was honored with prestigious Russian literary awards. In 2014, after Donetsk got occupied by the Russian troops, Rafieienko moved to Kyiv and switched from Russian to Ukrainian as the main idiom of his creative self-expression. “Mondegreen” is the writer’s first novel that he wrote in Ukrainian; therefore, numerous language and psycholinguistic transformations, depicted in the book, are of great interest to both readers and linguists. The article analyzes the main features of the novel’s language, particularly the usage of synonymic lines, specifications, quotations, word games regarding the characters’ names and toponyms, etc. In the main protagonist’s memories, the landscape of his native Donbas remains nameless. It visibly contrasts with the depiction of Kyiv: there, all the places that the character visits have their modern names, including local districts, streets, shops, and cafes. It is a symbolic representation of the refugee’s small homeland — the territory alienated from the est of the state by enemies’ aggression and disappearing from the map of Ukraine. The novel’s main storyline relates to the new linguistic and historical experience that Habinsky (the author’s alterego) acquires thanks to the Ukrainian language. Therefore, this research sheds light on the dominant idea of the novel: it demonstrates the importance of the mother tongue in the restoration of the individual’s connection with their ancestors, especially in the context of the nation’s historical memory and Ukrainians’ tragic experience during the 20th century. Keywords: code-switching, word play, citation, linguistic memory, historical memory.
Vidapellative microtoponyms of Zhytomyr region: history of formation and semantics
Authors:   Institute of the Ukrainian Language of the National Academy of Sciences of Ukraine, Sarhan Nadiia
Published: October 2023

The ethno-cultural region of Polissia is located on the territory of modern Ukraine and Belarus. As a result of wet, woody and marshy terrain which is caused by the phisico-geographical properties of the territory, the population density is low. Consequently, the array of traditional intangible culture, which is reflected in microtoponyms, has been well preserved due to the peculiarities of their creation and functioning. Taking this into consideration, their fixation and research is an important task for modern onomastics, linguistics and many other scientific areas. This article is dedicated to the research of Zhytomyr Polissia’s microtoponyms, originating from geographical terms (e.g. Vidʹma, Hvizdʹ, Vyla, Sazhavka, Hrebinetsʹ, Topylo, etc.). The comparison of the studied names with the similar onyms of other Ukrainian regions, has made it possible to observe the difference in the meaning of the appellative, which has formed the basis of microtoponyms in different territories (e. g. Topilʹnia, Hrebinetsʹ). Microtoponyms with the same meaning, but different pronunciation (e. g. Sazhalka — Sadzhalka — Sazhavka) are representative as well. The study of some names has been required a detailed examination of the adjacent object’s names. Let us examine it with the geographical term “hvizdʹ”, which has become a word-formation for the similary named microtoponym. This lexeme has been regarded unknown to the Eastern Slavs for a long time. The overwhelming amount of the natural boundaries’ proper names, formed by the forest trees’ names (e. g. Hnylyi Dub, Velykyi Lis, Zaberezzia, Lypnyk, etc.), confirmes that the appellative “hvizdʹ” has remained the meaning of the word ‘wood’ on the reaserched area. Therefore, the microtoponyms of Zhytomyr Polissia’s research demonstrates: a strong correlation between geographical terminology based on the proper names and the studied area’s natural features; the difference in pronunciation and semantics of word-building lexemes, depending on the region’s dialect characteristics; the historical context’s influence on the name forming process. Keywords: microtoponym, geographical term, Polissia, influence of natural features on onimization.
ANALYSIS OF ANTHROPOMETRIC AND PHYSICAL CHARACTERISTICS OF ATHLETES ENGAGED IN ARTISTIC GYMNASTICS AND ARTISTIC SWIMMING
Authors: Markov A. , Dzimbova T.
Published: October 2023

Aesthetic sports, in addition to specific skills, also require athletes to have a certain appearance. This appearance contributes to the positive attitude of the audience and judges towards the respective athlete, but on the other hand, it helps in the execution of the complex elements of the combination. PURPOSE. The aim of the present study is to compare the body composition and somatotype of female artistic swimming and gymnastics and to evaluate lower limb strength and breath holding times in both groups. METHODS. Six female gymnasts (11.2 ± 2.6 years) and 6 artistic swimmers (11.2 ± 2.2 years) participated in the study. To achieve this goal, the female athletes visit the Center for Functional Research in Sports and Kinesitherapy at SWU “Neofit Rilski” once, where the research is carried out. RESULTS. The results of the conducted research show that even at this early childhood age, female athletes in both sports have received the appropriate adaptations characteristic of the given sport. Gymnasts have developed good explosive power of the lower limbs, with their vertical jump averaging about 10 cm greater than that of swimmers. While swimmers, on the other hand, hold their breath for a longer period of time, on average about 37 seconds longer than gymnasts. CONCLUSIONS. Properly targeted training in the given sport leads to appropriate adaptations that favor the performance of the athlete.
BIOMECHANICAL SUBSTANTIATION OF THE ALGORITHM FOR CHOOSING THE OPTION OF DISTAL CORRECTIVE OSTEOTOMY OF THE II–IV METATARSAL BONES IN THE TREATMENT OF METATARSALGIA
Authors: Prozorovskiy Dmytro , Karpinsky Mykhailo , Karpinska Olena
Published: October 2023

Deformations of the front part of the foot with valgus deformity of the first toe lead to a redistribution of the body weight load during walking between the heads of the metatarsal bones. At the same time, the load on the head of II and III, and sometimes IV metatarsal bones increases significantly. Objective. To substantiate the choice of the most correct distal metatarsal osteotomy for the treatment of patients with metatarsalgia. Materials and methods. Three variants of distal metatarsal osteotomy were simulated: Weil, Helal, and distal wedge-shaped metatarsal osteotomy. Result. Weil osteotomy allows you to raise the support point of the metatarsal head above the support surface from 2 to 7 mm, depending on the amount of displacement of the head in the proximal direction and the angle of inclination of the metatarsal bone relative to the plane of the support surface, which effectively reduces the load on the metatarsal head during walking, but under conditions of magnitude the angle of inclination of the axis of the metatarsal bone is more than 20°. Helal osteotomy with the subsequent displacement of the separated part proximally, ensures the lifting of the head above the conventional plane of support from 1 to 4 mm, contributes to the effective unloading of the head while standing and while walking. They are used only for severe metatarsalgia. The range of correction of the standing height of the support surface of the metatarsal head for performing a distal wedgeshaped osteotomy is determined to be from 0.6 to 2.9 mm. Its advantage is the independence of the amount of correction from the presence or absence of a decrease in the longitudinal arch of the foot. Conclusions. Weil osteotomy has the worst corrective possibilities of raising the head of the metatarsal bone, but is very easy to perform, so its use is advisable in the absence of reduction of the longitudinal arch of the foot. A wedge-shaped distal osteotomy has a range of correction of the metatarsal headelevation up to 3 mm, but it depends on its diameter, so it is used in the case of a head diameter of at least 10 mm. Helal osteotomy provides the widest range of elevation of the metatarsal head, which does not depend on the presence of any degree of flat feet, but has some technical limitations.
Faithful Sets of Topological Descriptors and the Algebraic K-Theory of Multi-Parameter Zig-Zag Grid Persistence Modules
Authors:   ,   Montana State Univeristy, Schenfisch Anna Katherine
Published: October 2023

Given a geometric simplicial complex, the uncountable set of (augmented) persistence diagrams corresponding to lower-star filtrations taken with respect to all possible directions uniquely correspond to the simplicial complex, i.e., the set is faithful. While this hints towards interesting applications in shape comparison, the set of all possible directions is uncountably infinite, and so has no hope of computability. In practice, one might use a finite approximation, but faithfulness of this approximation is not guaranteed. Motivated by the need for both computability and provable faithfulness, we provide an explicit description of a finite faithful set of augmented persistence diagrams. We then show this construction applies to augmented Euler characteristic curves and augmented Betti curves, and is stable under particular perturbations. In the specific case where the underlying complex is a graph, we provide an improved construction that utilizes a radial binary search. We then shift focus to comparing the cardinalities of minimal faithful sets of descriptors as a way to define and order equivalence classes of topological descriptor types. Focusing on six topological descriptor types commonly used in practice, we give a partial order on their corresponding equivalence classes, as well as give bounds on the sizes of minimum faithful sets for each descriptor type. Next, we broaden our view to zig-zag grid persistence modules, functors whose domain categories are posets with grid-like structure. We begin by explicitly defining such persistence modules in terms of constructible cosheaves over stratified Euclidean space, including a careful treatment of augmented persistence modules, which are analogous to the aforementioned augmented descriptors who played a central role in discussion of faithful sets. Exodromy gives us an equivalence between persistence modules as a functor category and as constructible cosheaves; we furthermore show the equivalence of these categories with a category of constructible functors out of R^d with a fixed stratification and localized at weak equivalences, essentially “standardizing” modules so that the category has a clear monoid structure. We compute the algebraic K-theory of zig-zag grid persistence modules, using a double inductive argument to show the K-theory is additive over strata. Finally, we identify connections to related topics, such as the virtual diagrams of Bubenik and Elchensen, as well as Euler characteristic and Betti curves/surfaces/manifolds. We hope a study of K-groups will provide interesting insights into the nature of persistence modules, and we indicate ways in which the zeroth and first K-groups may be interpreted.
Symbiotic nurture between literature, culture and nature in Gary Snyder’s Meta-Picto-Poetry of landscape
Authors: Bi Jiancheng
Published: October 2023

Abstract: This article holds the opinion that some meta-picto-poetry of landscape, composed by American poet Gary Snyder, takes Chinese landscape painting as its subject matter with the characteristics of ancient Chinese poetry, shimmering with incomparable artistic charm and cultural substance. Poetry of this kind is a perfect combination of eastern and western elements, integrating the cultures, thoughts and arts of both sides. The appreciation of this poetry creates a complex experience with a hybrid of artistic forms and aesthetic spaces. Gary Snyder is not only an eco-poet, but also a stylist and a man of practice. His poetic works reveal the fostering relationship between literature, culture and nature. The article intends to make a cross-cultural, interdisciplinary and multi-field attempt in Snyder’s criticism, with analytical methods inclusive of eastern and western cultures, ancient and present visions as well as dynamic and static experiences.
O princípio do comum como apófase ao princípio da propriedade nas democracias contemporâneas
Authors: Decothé Jr. Joel
Published: October 2023

Resumo: A implicação filosófica que guia o problema aqui tratado é a seguinte: como o princípio do comum se constitui em apófase frontal ao princípio da propriedade, nas democracias contemporâneas? Não se pretende oferecer uma resposta exaustiva para esse problema. No entanto, utiliza-se a estratégia argumentativa de dividir este escrito em três seções: (i) investigar especulativamente a tensão dialética entre o princípio do comum e o princípio da propriedade; (ii) observar analiticamente a premissa que se coloca como contribuição às práticas comportamentais de individualismo exacerbado, como ato de aversão ao princípio do comum e (iii) deter-se na articulação da noção de princípio do comum, como fator que está presente no limiar entre o vulgar filosófico e o universal filosófico. Por fim, fazem-se algumas considerações que problematizam a noção naturalizada de princípio da propriedade, nas democracias atuais, tendo em vista o poder constituinte que o princípio do comum detém na perspectiva de realização do bem-estar dos agentes humanos, na vida comunitária contemporânea.
Francis Bacon e a imagem do livro da natureza
Authors: Hirata Celi
Published: October 2023

Resumo: No artigo, explora-se a concepção da natureza como livro, em Francis Bacon. Por um lado, utilizando essa imagem e confrontando a leitura do livro da natureza e a leitura dos livros dos autores consagrados, Bacon contrapõe duas vias completamente distintas da filosofia natural: a interpretação da natureza em contraste com a via da antecipação da mente. Por outro, ao se referir ao livro revelado e ao livro das criaturas como dois volumes distintos da mesma autoria, Bacon pleiteia a especificidade da investigação científica da natureza e sua relativa autonomia, em relação ao âmbito da religião, ao mesmo tempo que mostra o caráter de continuidade e complementação dos dois livros.
Implementation of strategies and programs for breastfeeding, complementary feeding, and malnutrition of young children in Brazil: advances and challenges
Authors: Venancio Sonia Isoyama , Buccini Gabriela
Published: October 2023

Abstract: Malnutrition in all its forms has risen on global agendas due to the recognition of its magnitude and consequences for a wide range of human, social, and economic outcomes. Implementing strategies and programs with the needed scale and quality is a major challenge. The Brazilian National Survey on Child Nutrition (ENANI-2019) pointed out several advances but numerous challenges. In this paper, we reflect on the implementation progress of breastfeeding, complementary feeding and young children malnutrition strategies and programs in Brazil and how existing challenges can be overcome through the lens of implementation science. First, we present a brief history of such programs. Second, we selected two breastfeeding initiatives to illustrate and reflect on common implementation challenges. In these case studies, we used the RE-AIM (Reach, Effectiveness, Adoption, Implementation, Maintenance) framework to analyze the implementation and scaling up barriers and facilitators. We found common barriers related to unclear goals about the reach of programs, challenges in assessing effectiveness and fidelity/quality during the real-world implementation, discontinuation or lack of funding, and lack of monitoring and evaluation impacting the sustainability of programs. We also discuss the use of implementation science to achieve adequate nutrition by 2030 and present critical elements for successful scale implementation of nutrition programs based on global evidence. Despite the investment to implement different actions aimed at facing infant feeding and malnutrition, high-quality implementation research must become a priority to catalyze progress in Brazil.
METODOLOGIAS ATIVAS NO ENSINO SUPERIOR: UM MAPEAMENTO SISTEMÁTICO NO CONTEXTO DOS CURSOS DE ENGENHARIA
Authors: REIS ALAN , ALVES ALAINA , WENDLAND EDSON CEZAR
Published: October 2023

RESUMO: As metodologias ativas podem ser entendidas como alternativas pedagógicas que colocam o foco do aprendizado nos estudantes. Com mediação de docentes competentes, os alunos aprendem a partir da descoberta, da investigação e por problemas. Tais metodologias comumente promovem uma maior retenção e compreensão de contéudos ensinados, uma vez que o aprendiz se encontra engajado nas atividades, seja por meio de pesquisa, colaborações em grupo, discussão e resolução de problemas. Este trabalho teve como objetivo verificar a evolução temporal do uso de metodologias ativas, no contexto dos cursos superiores de Engenharia, a partir de um mapeamento sistemático da literatura. A partir de um protocolo de pesquisa estabelecido, buscou-se verificar quais os principais pesquisadores desta área, sua localização geográfica e quais as metodologias preferidas no contexto destes cursos. A partir dos resultados, foi possível observar que o crescimento do número de publicações científicas sobre metodologias ativas no contexto da Educação em Engenharia, em especial nos últimos cinco anos do período analisado (entre 2015 e 2020). Pode-se notar a realização de pesquisas neste contexto em todos os continentes, com predomínio de estudos liderados por pesquisadores americanos e europeus. Nos estudos mapeados, a sala de aula invertida e a aprendizagem baseada em problemas foram as metodologias mais identificadas. Isso indica uma maior preocupação dos professores da área em promover atividades com elevado envolvimento, que permitam o desenvolvimento de habilidades e competências pessoais e profissionais, ainda no período de formação.
Perspectivas de pacientes sobre a vivência da psoríase: um estudo qualitativo com base na teoria Junguiana
Authors: Vieira Camila Martins , Vanderlei Lygia Carmen de Moraes , Barbosa Leopoldo Nelson Fernandes , Nascimento Ananda Kenney da Cunha , Dias Mirian Rique de Souza Brito , Cabral Filho José Eulálio
Published: October 2023

RESUMO A psoríase é uma doença inflamatória e crônica de pele, de natureza benigna, sistêmica, imunomediada e não contagiosa. Pretendeu-se compreender as expressões simbólicas da psoríase e suas repercussões no processo de individuação de pacientes adultos por meio de uma pesquisa qualitativa descritivo-interpretativa. Utilizada entrevista aberta, técnica de análise de conteúdo temática e referencial teórico da Psicologia Analítica. Amostra de dezesseis participantes com psoríase em tratamento ambulatorial. Delineadas as categorias: psoríase como símbolo: surgimento, crises e remissão; rotina de tratamento: da fronteira da pele ao mundo interior; e, si-mesmo: vereda de aproximações e afastamentos. O desenvolvimento do adulto com psoríase foi compreendido pelas vivências simbólicas que apontaram para alterações na saúde integral. No entanto, reconheceu-se que as relações entre psique e corpo, apesar de conflituosas, proporcionaram aprendizados e favoreceram o processo de individuação.
Biventricular aneurysm in a dog
Authors: Montagnini Karim Cristhine Pase , Ferronato Amália , Smaniotto Crisan , Goulart Juliana das Chagas , Almagro Larissa Donat , Viott Aline de Marco
Published: October 2023

ABSTRACT: An aneurysm is defined as a localized dilation of a blood vessel or heart. It may have either a congenital or an acquired origin and occurs in both humans and animals. Cardiac aneurysms are rare, and are characterized by sacculations of the cardiac wall. The present case report describes the macroscopic and microscopic findings of an aneurysm affecting both ventricles of the heart in a dog. A 7-year-old mixed-breed female dog with osteosarcoma on the left pelvic limb was euthanized and submitted to the veterinary pathology laboratory for necropsy. Macroscopically, besides the lesions in the link, the pericardial sac was adhered to the pericardial surface of the heart and there were two sacculations in both ventricles which communicated widely with the respective ventricle. Microscopically, fibrous tissue adhered to the pericardium, atrophy and necrosis of the cardiomyocytes with replacement by adipocytes were observed in addition to hyperplasia of the tunica media of arterioles and thrombosis. A diagnosis of acquired biventricular cardiac aneurysm was made based on the necropsy findings and microscopic lesions in the heart. We emphasize the importance of performing a necropsy and examining tissues histologically for the diagnosis of this rare condition. Ventricular aneurysms should be included in the differential diagnosis of cardiovascular disease in dogs.
Intramuscular epithelioid hemangiosarcoma in a horse
Authors: Santos Igor Ribeiro dos , Lamego Éryca Ceolin , Cecco Bianca Santana de , Lorenzett Marina Paula , Bandinelli Marcele Bettim , Driemeier David , Pavarini Saulo Petinatti
Published: October 2023

ABSTRACT: A 20-year-old, sexually intact male Dutch Warmblood horse was presented with a 5-day history of difficulty moving and non-flexion of the right pelvic limb, followed by subcutaneous swelling and permanent lateral decubitus. Despite attempts at palliative care, the horse was euthanized after clinical worsening and lack of treatment response. The main gross finding was a soft, red-to-black, lobulated mass involving the right semitendinosus, semimembranosus, and biceps femoris muscles. Soft, red nodules were also seen in all pulmonary lobes and adrenal glands. Histology revealed neoplastic proliferation of malignant polygonal cells, occasionally arranged in irregular anastomosing vascular channels filled with erythrocytes. Neoplastic cells were immunoreactive for factor VIII-related antigen, confirming the blood vascular origin. A final diagnosis of epithelioid hemangiosarcoma was made. These findings reinforced the inclusion of hemangiosarcoma as a differential diagnosis of equine muscular lesions and highlighted the histological features of the epithelioid hemangiosarcoma subtype.
ANÁLISE DE POSICIONAMENTOS PÚBLICOS SOBRE A LICENÇA SOCIAL PARA OPERAR DA MINA GUAÍBA - RS
Authors: Tomaz Pedro Luz , Flôres Rafael Kruter
Published: October 2023

RESUMO Licença Social para Operar - LSO é um conceito utilizado tanto como mecanismo estratégico de empresas, para obter aceitação de seus empreendimentos, quanto como elemento de reivindicação por parte de movimentos sociais que os confrontam. Este trabalho analisa posicionamentos públicos feitos sobre o projeto Mina Guaíba, no Rio Grande Sul. Foram identificados os posicionamentos no processo de licenciamento e em audiências públicas, e analisados 36 textos de portais da internet e 8 trabalhos acadêmicos. Os posicionamentos foram analisados de acordo com elementos encontrados na literatura, traçando paralelos com os posicionamentos expostos e os fatos descritos sobre a Mina Guaíba. Foi possível concluir que existem importantes relações entre os posicionamentos públicos sobre o projeto da Mina Guaíba e as questões analisadas em estudos empíricos sobre a obtenção da LSO em nível internacional. Problemas como o economicismo retórico em prol dos empreendimentos, a manipulação dos espaços de consulta, as omissões em relação aos reais impactos ambientais dos projetos e a crise de confiança vivenciada pelo setor de mineração se fazem constantes em ambos os casos. O artigo contribui com o debate sobre LSO ao apontar a relevância das ações organizadas por movimentos sociais e organizações ambientalistas no sentido de conscientização social.