bluuebunny/crossref_metadata_2025 huggingface dataset:
Affect and Sensation
Authors: Sampson Ellen
Published: November 2020

“Affect and Sensation” brings together cyanotypes and text from the practice-based project “The Afterlives of Clothes” to explore the sensory and emotional effects of archival fashion research. Addressing the ways that imperfect garments make the absent bodies of those who used, made, and repaired them present for us, the works are a call to engage with the intricacies of wear, gesture, and trace. Initially developed during a fellowship at The Costume Institute of the Metropolitan Museum of Art and later a residency at Bard Graduate Centre, the broader project asks how, in a field where absent bodies and narratives are already understood as problematic, presenting the traces of use might re-contextualize objects which would otherwise be excluded from view. Focusing on accessories, objects which Jones and Stallybrass term “detachable parts” of the self (2001b: 116), the images and writing draw upon a methodology that combines archival research with auto-ethnographic writing, image, and filmmaking to explore the embodied and bodily experience of researching imperfect garments in museum archives. Presenting archives as repositories of affect, labour, emotion, and bodily trace, they ask how ideas of affect and containment might shed light on the encounter with archival garments. This project presents garments in archives as both containers and producers of affect — an affect that, in part, stems from the bodies that wore and made them, but also from the multiple meanings that they acquire through accession, storage, conservation, and display.
You Aren’t What You Wear: An Exploration into Infinifat Identity Construction and Performance through Fashion
Authors: Evans Calla
Published: November 2020

Through remote wardrobe interviews with five self-identified infinifat participants, this paper explores how those existing in a body larger than a US dress-size 32 access fashion. The majority of research that has occurred at the intersection of fat studies and fashion studies has focused on the fashion and dressing experiences of women who fit the conventional definition of “plus-size.” Commercially available, mass-produced fashion options drop off dramatically for women larger than a US dress-size 28 and become almost non-existent for those who are a size 32 or larger. By focusing on infinifat or superfat people who exist beyond a size 32 I draw attention to the impact that the lack of access to fashion has on the subjectivities infinifat people can perform. The findings in this paper build from existing literature on plus-size dressing that focuses on limitations in identity construction and performance experienced by those who are able to access commercially available plus-size fashion. Without readily available, situationally-appropriate clothing, infinifat and superfat people are limited in the subjectivities they can perform and are excluded from specific social spaces. This exclusion serves to remarginalize an already marginalized group and is felt most acutely by those who embody additional marginalized identity markers, such as those who are racialized or living in poverty. In this way, the findings presented in this paper further address the infinifat-sized gain existing literature on plus-size dressing and lay the foundation for future work that engages with the infinifatshion community.
Fashioning the Academic and Private Self: The Clothing of Johanna Westerdijk in the Context of her Biography
Authors: Kargól Marta
Published: November 2020

This article aims to analyze the clothing of Dutch botanist Johanna Westerdijk (1883–1961) in connection with her biography, academic career, and character. A thorough analysis of changes and constants in her clothing reveals her personal style and approach to fashion, made possible due to the significant number of Westerdijk’s portraits — the primary source for this study. Her sartorial sense, as seen in these photographs, mirrors the manner in which Westerdijk defined herself, both as a woman and scholar. The variety of Westerdijk’s portraits allow us to analyze her clothing during official ceremonies, at work, in daily life situations, her travel outfits as well as her dressing-up and cross-dressing practices. This article indicates that these visual sources provide interesting insights into how Westerdijk fashioned herself. The purpose of the article is to investigate the extent to which research into biography and dress history can be mutually illuminating.
The Kurious Kase of Kim Kardashian's Korset
Authors: McKnight Alanna
Published: November 2020

The 2019 Met Gala’s theme was based on the Susan Sontag essay “Notes on Camp,” and the celebrity attendees had a broad range of interpretations. The look that caused the most controversy was worn by the reality TV star Kim Kardashian, in a Thierry Mugler dress and Mr. Pearl corset. Rather than focus on the design, the first for Mugler since 2002, or how the dress fit into the theme, critics instead chose to focus on the corset and repeat a rhetoric about the controversial garment that has been recurrent for over a hundred years. There is a long tradition of opposition to corsets, including claims that the accessory is bad for the health of the wearer, that corsets are unnatural, and that they are anti-feminist. This article explores the history of corsets, health, popular culture, and fashion, using Kardashian as a contemporary source of examination. Kardashian’s body is a site of controversy, much like corsets, as she wears and sells shapewear. The critique of Kardashian’s use of modern shapewear reflects a long tradition of controlling women’s bodies through dress reform and medical intervention, a debate the Met Gala dress reignited.
Effect of Low Level Laser Therapy on Gingival Inflammation in Patients undergoing Fixed Orthodontic Treatment: A Randomized Clinical Trial
Authors: Aly Eman , Hafez Hend Salah , Labib Amr Hussein , Harhash Tarek Abdel Hamid , El-Yazeed Mohamed Abou , Gaber Sylvana , Nasr Shaimaa
Published: November 2020

AIM: The aim of this study was to compare the effect of low level laser therapy (LLLT) with non-LLLT as an adjunct to mechanical debridement in patients who develop gingival inflammation during fixed orthodontic treatment.
MATERIALS AND METHODS: Thirty subjects undergoing comprehensive fixed orthodontic treatment were randomly allocated. Split mouth design was applied for each patient, where the four quadrants were randomly allocated to receive full mouth debridement. The test group (quadrant) received three laser sessions (days 1, 3, and 5) besides debridement while the control group (quadrant) received debridement only. Both bleeding index (BI) and plaque index (PI) were measured after 1 and 3 months, while the total colony forming units (CFU) were measured after 2 and 6 weeks.
RESULTS: Clinical assessments (BI and PI) showed a statistically significant decrease at the first follow-up (after 1 month) and a slight increase in the second (after 3 months) that did not reach the base line. While, the total CFU showed a significant decrease in both follow-ups.
CONCLUSION: Laser showed superior results in the treatment of gingival inflammation induced by fixed orthodontic appliances other than debridement only.
Identification of Sentinel Lymph Node in Breast Cancer with three Tracers (Radiocolloid, Methylene blue, and Indocyanine Green). (Case Report)
Authors: Kondov Goran Borislav , Gruev Viktor , Stojanovski Sinisha , Bogdanovska-Todorovska Magdalena , Colanceski Risto , Srceva Marija , Jovanovska Anamarija , Stojkovski Zlatko , Kondov Goran
Published: November 2020

BACKGROUND: Sentinel lymph node (SNL) biopsy in breast cancer for the determination of axillary status is standard procedures in surgical treatment of early-stage breast cancer. The identification of the SNL is usually performed by radiocolloid injection or/and injection of methylene blue due. The use of indocyanine green (ICG) dye, which is fluorescent dye, which movement in breast and axillar pit, can be followed with special cameras which detect near infrared specatar of light.
CASE REPORT: In this paper, we present case report of patient with breast cancer, where we perform SNL detection with three methods: Use of radiocolloid which we trace with static gamma camera, and intraoperatively with hand held gamma probe, methylene blue dye which movement we followed by eye contact and using indocyanine green which movement was followed by specially constructed multispectral camera, which can detect near-infrared fluorescence that is emitted by ICG and methyline blue, respectively.
CONCLUSION: Fluorescent imaging with ICG is a sensitive, valuable, and safe method for SNL biopsy. Finding new agents that would identify the SNL, especially if they are not radioactive would be an important step in wider application of this method.
Left Hemiparesis in Acute Myeloblastic Leukemia with High Mortality
Authors: Limijadi Edward Kurnia Setiawan , Harbani Noegroho , Widorini Nani , Budiwijono Imam
Published: November 2020

BACKGROUND: Leukemia is a blood malignancy that has a variety of types with a variety of clinical manifestations in the body organs in each patient. Acute myeloblastic leukemia (AML) occurs more frequently in adults with clinical manifestations in the central nervous system, especially on the M4 and M5 subtypes.
CASE REPORT: A 42-year-old woman came with a complaint of sudden left hemiparesis. The laboratory results obtained leukocytosis, normochromic normocytic anemia, and thrombocytopenia. Peripheral blood smear found immature cells of the myeloblasts and monoblasts series and monocytosis.
CONCLUSION: The conclusion of the clinical diagnosis and laboratory of the patient is left hemiparesis caused by AML with the suspect of subtype M4 or M5. Patients died within a few hours later, so bone marrow puncture and brain fluid retrieval for malignant cell analysis could not be performed. Brain fluid analysis is important to be performed to enforce the diagnosis of cerebral leukemia.
Modern Diagnostics of Sepsis and Septic Shock in Children
Authors: Bulatova Yekaterina Y. , Maltabarova Nurila A. , Zhumabayev Murat B. , Li Tatyana A. , Ivanova Marina P.
Published: November 2020

Sepsis is still one of the leading causes of child mortality worldwide, despite advances in its diagnosis and treatment. Difficulties in recognizing the transition of a localized infectious-inflammatory process to a generalized one lead to a belated diagnosis and the beginning of therapy. Meanwhile, the earlier treatment is started, the higher the patients’ chances of life. Early diagnosis of sepsis, which corresponds to modern ideas about this condition, is one of the main tasks for both scientists and practitioners. The aim of this review is to study modern recommendations for the diagnosis of sepsis and septic shock in children. The article reflects the epidemiology, etiological features, modern definitions, and methods of diagnosis of pediatric sepsis.
Public Health Risk Assessment Due to Air Pollution in the Temir District of the Aktobe Region
Authors: Sakebayeva Laura , Sabyrakhmetova Valentina , Karashova Gulsim , Aitmaganbet Perizat , Shayakhmetova Kulyan
Published: November 2020

BACKGROUND: This article focuses on the health risk assessment associated with air pollution for the population of the Temir district in the Aktobe region. The risk assessment of the effects of air pollution on public health revealed a tendency to deterioration in the health indicators of the children’s population.
AIM: The research object was the population of the Temir district living near the oil and gas field Zhanazhol.
METHODS: The work was carried out according to the risk assessment methodology described in the manual R 2.1.10-1920-04. The maximum non-carcinogenic risk due to exposure to chemicals in the air basin of residential areas was established for children from 0 to 6 years of age in the Temir district.
RESULTS: A high risk of respiratory, blood, and cardiovascular diseases was observed. Sulfur dioxide, hydrogen sulfide, nitrogen, and carbon oxides contained in atmospheric air contribute to the risk of developing these diseases. The levels of carcinogenic risk to public health in the Temir district show that the maximum individual risk of oncological diseases is observed in the group of children. The risk of malignant neoplasms in adolescents is 1.2 times lower, in the male population – 1.4 times lower, on average, and in the female population – 1.3 times lower than in children. Public health risk analysis aims to select the best ways in a particular situation to eliminate or reduce risk associated with air pollution for the population.
CONCLUSION: The methodology of a comprehensive health risk analysis is a promising and developing approach in the system of monitoring the quality of the human environment and assessing environmental hazards.
The Effect of Lavender and Rose Aromatherapy on the Intensity of Active Phase Childbirth Pain in the Manyak Payed Community Health Center, Aceh Tamiang Regency, Indonesia
Authors: Manaf Salmiani Abdul , Yuniwati Cut , Dewi Silfia , Harahap Lili Kartika
Published: November 2020

BACKGROUND: Most postpartum mothers experience pain. Childbirth pain can cause anxiety, fear, tension, and stress. To increase comfort and reduce pain in maternity can be done using non-pharmacological methods by giving aromatherapy.
AIM: The aim of the study was to analyze the effect of lavender and rose flower aromatherapy on the intensity of active phase childbirth pain in pregnant women in Manyak Payed Community Health Center, Aceh Tamiang Regency, Indonesia
METHODS: A quasi-experimental design with a prospective cohort study with post-test control group design, which was conducted in the Manyak Payed Community Health Center working area from September to December 2019. A total of 54 women giving birth using accidental sampling techniques were selected as samples and divided into three groups. Each group numbered 18 people. In this sample using inclusion and exclusion criteria, data analysis uses univariable and bivariable using Kruskal–Wallis H test and Mann–Whitney test.
RESULTS: The results obtained mean childbirth pain in the lavender group by 18.83, rose flower group by 26.21, and the control group by 37.06. The results of the crucial Willis H test show that there are differences ineffectiveness in the control group and the treatment group with the Sig. 0.001 (<0.05). In further tests of the post hoc test using the Mann–Whitney test, it was found that there was no difference in the effectiveness of the intensity of labor pain in the active phase I with a sig. 0.90 (p > 0.05). Lavender and rose flower groups were equally effective in the intensity of childbirth pain.
CONCLUSION: There is a difference between lavender and rose flower aromatherapy on the intensity of pain in the association. Lavender and rose flower aromatherapy treatments are equally influential on the intensity of labor pain in the first phase of the active phase in labor. Lavender and rose flower groups were equally effective in the intensity of childbirth pain.
The Relationship of Vitamin D Insufficiency with Low-Energy Fractures in Children
Authors: Alosaimi Majed Nasser , Qari Yousef Hussni , Alnasr Abdulaziz Abdulelah Abu , Barnawi Hani Ibrahim , Bazaid Abdullaziz Mohammad , Alotaibi Khalid Ayidh , Khan Muhammad Anwar
Published: November 2020

BACKGROUND: Approximately 50% of the world population are suffering from Vitamin D insufficiency. Vitamin D is one of the steroid hormones, which is a fat soluble vitamin that has a critical role in maintaining the homeostasis of bones. Low-energy fractures are defined as falling from the level of standing height or even less that usually should not result in fractures. Another study that was done in Jeddah on a sample of 510 children between the age of 4–15 taken in the pediatric clinic at Jeddah Clinic Hospital-Kandarah. 59% had relative deficiency, and 27% had a deficiency in 25-hydroxyvitamin D.
AIM: Therefore, this research is conducted to collect more evidences to assess the association between vitamin D level and low-energy fractures in children.
METHODS: The study group consisted of 14 children aged 3–15 years old with low-energy fractures and the control group consisted of 24 children in the same age without fractures. Vitamin D level was measured in each one of them and X-ray was obtained from the cases to prove the presence of low-energy fracture. The analysis plan that was used in this research is Fisher’s exact test to overcome the small sample size.
RESULTS: Vitamin D levels were found deficient in four cases, and eight of them were insufficient. Whereas, the normal level of Vitamin D was found in only two of the cases. On the other hand, in the control group the level of Vitamin D was deficient in four participants, and 15 others were found to be insufficient. Also, five of the participants were found to have a normal Vitamin D level. According to the results, low levels of Vitamin D were observed in both groups. A total of 23 out of 38 children enrolled in the study were found to have an insufficient Vitamin D level. The result of p = 0.718 which is not significant to prove the correlation between Vitamin D insufficiency and low-energy fractures.
CONCLUSION: In conclusion, this study did not show any relation between Vitamin D level and the presence of low energy fracture. Future studies are required to include more subjects and centers to their study or to compare the low energy fracture and high energy fracture in term of Vitamin D level.
Symptomatic Intracerebral Hemorrhage Complicating Intra-Arterial Mechanical Thrombectomy in Acute Ischemic Stroke
Authors: Amran Muhammad Yunus , Bahar Ashari
Published: November 2020

BACKGROUND: Acute ischemic stroke (AIS) is the most common type of stroke. The endovascular treatment of AIS depends on stroke subtype, whether caused by large vessel occlusion (LVO) or not. We presented a case of AIS due to LVO that has complication in the form of symptomatic intracerebral hemorrhage (sICH) after an intra-arterial mechanical thrombectomy.
CASE PRESENTATION: An 80-year-old woman was admitted to the emergency department with sudden onset left side weakness since <1 h before admission, when the patient had woke up in the morning. The patient had history of hypertension, diabetes mellitus, and dyslipidemia. She also had cardiac disorders in the form of non-valvular atrial fibrillation with 55% left ventricular ejection fraction (LVEF). Her blood pressure was 148/84 mmHg, heart rate was 65 beats/minute, respiratory rate was 17 times/min, and body temperature was 36.2°C. Glasgow coma scale (GCS) was E3V4M5; National Institutes of Health Stroke Scale (NIHSS) was 15. She had moderate aphasia. Head CT scan did not show any hyper- or hypodens areas and Alberta Stroke Program Early CT score was 10. RAPID automated CT perfusion using Quantitative Software showed that the mismatch volume was 192 ml and the mismatch ratio was 7.4. Endovascular therapy in the form of intra-arterial mechanical thrombectomy was performed, and blood flow in the right internal carotid artery (ICA) was restored with the score of Modified Thrombolysis in Cerebral Infarction (mTICI) was III. Follow-up non-contrast head CT scan was performed and revealed acute infarction with hemorrhagic transformation in the middle cerebral artery (MCA) territory.
CONCLUSION: Early and accurate treatment of AIS is paramount. Endovascular treatment in the form of intra-arterial mechanical thrombectomy is the current treatment recommendation in LVO although there is a risk of symptomatic intracerebral hemorrhage, as in this case.
The Analysis of Binahong Leaves Potential (Anredera cordifolia) as an Alternative Treatment of Anticataractogenesis
Authors: Feriyani Feriyani , Darmawi Darmawi , Balqis Ummu , Lubis Rodiah Rahmawaty
Published: November 2020

BACKGROUND: Cataract is a condition where the retina cannot capture images completely and causes blindness due to an imbalance of reactive oxygen species (ROS). These free radicals can be suppressed using antioxidants from several plants, one of which is binahong leaves.
AIM: The purpose of this study is to analyze the potential of binahong leaves as an initial screening that can play a role in inhibiting the process of cataractogenesis.
METHODS: By extracting binahong leaves with 60% ethanol, the extracts were tested for phytochemistry using the X technique and GC–MS using the Perkin-Elmer GC Clarus 500. The experimental process and all laboratory analyses were fully carried out from June to December 2019 at the Laboratory of Food Analysis and Yield Agriculture, Department of Agricultural Product Technology, Syiah Kuala University, Banda Aceh.
RESULTS: Analysis of binahong leaf potential showed that binahong leaves contain flavonoids, steroids, phenols, alcoholics, terpenoids, and saponins. While the GC–MS analysis results showed that binahong leaves are rich in phytol and contain fatty acids.
CONCLUSION: Binahong leaves have the potential to be anticataractogenesis because they contain compounds rich in antioxidants.
Conservative Management of the Horizontal Root Fracture in the Middle Third using Fiber Post as an Intraradicular Splint
Authors: Vaswani Sneha Dhruvkumar , Abraham Sathish , Najan Harshal Balasaheb , Karad Rohini Ramesh
Published: November 2020

BACKGROUND: Root fractures are uncommon injuries in permanent teeth and account for only 0.5–7% of dental trauma. It occurs more frequently in fully erupted permanent teeth, in which the completely formed root with closed apices is solidly supported in the bone and periodontium. This may lead to complex consequences due to the combined damage to the pulp, dentine, cementum, bone, and periodontium. They are transverse to oblique in direction and result from a horizontal impact. Their incidence is more in the middle third of the root than at the cervical and apical thirds.
CASE REPORT: This paper describes a case of complicated horizontal root fracture at the middle third of the maxillary right central incisor. After receiving an endodontic treatment, the fractured root fragments of the maxillary right central incisors were united with the help of a glass fibre post. Eventually, the incisor was restored with a zirconia crown.
CONCLUSION: Follow-up after a year revealed a well-stabilized assembly of the root fragments and the post.
Causes and Risk Factors of Hospitalization among Under-five Children in Kassala, Eastern Sudan
Authors: Hassan Ahmed A. , Taha Zainab , Abdulla Mohammed A. , Ali AbdelAziem A. , Adam Ishag
Published: November 2020

BACKGROUND: According to the World Health Organization estimation, African Region deaths of all under-five deaths in 2015 were over 5 times higher in comparison to the European Region.
AIM: The study aimed to estimate the prevalence, investigate the possible causes and risk factors associated with under-five children’s hospitalization in Kassala, Eastern Sudan.
METHODS: A community-based cross-sectional study was conducted from December 2015 to March 2016. The data were collected by interviewing mothers.
RESULTS: A total of 297 mother-child pairs participated in the study. The mean (SD) of maternal age and children’s age was 27.6 (5.9) years and 16 (11.3) months, respectively. One hundred and three children were hospitalized over the past 6 months. The most common mentioned causes for the last hospitalization were gastroenteritis 28.1% (29/103), respiratory tract infections 19.4% (20/103), malaria 9.7% (10/103), and trauma 3.8% (3/103). In multivariable analysis, a high birth order (adjusted odds ratio [AOR] 1.25, 95% Confidence Interval [CI] (1.06, 1.47), low paternal education (AOR 2.89, 95% 1.32, 6.30), and bottle feeding (AOR 2.26, 95% CI 1.30, 3.80) were associated with under-five children’s hospitalization.
CONCLUSIONS: More than one-third of the children were hospitalized in Eastern Sudan. Urgent action is required to address children’s health issues (i.e., the above-mentioned causes and associated factors).
Breast Milk Macronutrients in Relation to Infants’ Anthropometric Measures
Authors: Abdelhamid Enas R. , Kamhawy Alyaa H. , Elkhatib Alshaimaa A. , Megawer Amr S. , El Shafie Amal I. , El Gendy Yasmin G. , Rabie Dina E. A.
Published: November 2020

BACKGROUND: Breast milk (BM) is the main nutritional source for newborns before they are capable to eat and consume other foods. BM has carbohydrates, lipids, complex proteins, and other biologically active components which have a direct effect on infant growth.
AIM: The aim of the study was to correlate anthropometric data of the infant to macronutrients in BM (fat, protein, and carbohydrates) and to find some modifiable issues affecting macronutrient contents of BM for the benefits of upcoming infants.
METHODS: One hundred breastfeeding mothers participated in the study, they were recruited from the outpatient clinic, El Demerdash Hospital, Ain Shams University, from September 2019, to December 2019. BM was expressed by an electric pump, macronutrient content was assessed. Anthropometric data of the babies and mothers were obtained, gestational age, parity, age of the women, and the route of birth were recorded.
RESULTS: For the macronutrients content of milk, a positive significant correlation was observed between BM fat, protein, and lactose. Infants’ body mass index (BMI) was negatively related to the fat content of BM, while no relation was found between BMI and protein or lactose content of the milk. BM fat content was negatively correlated with gestational age and maternal age. Positive correlations were found between BMI and protein, lactose and infant age. Protein content was negatively correlated with parity. No impact of infant’s sex on BM composition and as regards maternal diet, high protein consumption leading to increase BM protein content.
CONCLUSIONS: The current study confirms that BM macronutrient composition has a wide variability; this variability is associated with each macronutrient, respectively. To improve BM composition, one could aim for improving the nutritional balance in lactating women, especially for protein intake. More well-designed longitudinal studies about factors that influence human milk compositions are warranted.
Unilateral Renal Cystic Disease: A Case Report and Literature Review
Authors: Darmadi Darmadi , Ruslie Riska Habriel , Siregar Nurlaila Qodrianti , Theo Deli , Anas Syahrial
Published: November 2020

BACKGROUND: URCD is a rare disease characterized by cysts with various sizes in a diffusely enlarged kidney without forming a distinct encapsulated mass. We present literature review and report a case of URCD in our center. The aim of the study was to report a case of unilateral renal cystic disease (URCD) in a 25-year-old female.
CASE REPORT: The patient was a 25-year-old female. She came to emergency unit of Mitra Medika Amplas Hospital Medan, Indonesia, with dyspepsia associated symptoms. Physical examination and family health-related history were normal. Laboratory examinations and genetic evaluation showed no abnormalities. Ultrasonography examination revealed multiple cysts in her right kidney which was confirmed by computed tomography (CT) scan. The diagnosis of URCD was confirmed. No specific treatment was given and she was advised to do a routine follow-up.
CONCLUSION: URCD may present with mild symptoms or even asymptomatic. Diagnosis is confirmed by imaging modalities with normal renal function and absence of genetic predisposition. The management is conservative. Routine follow-up is mandatory.
The Effect of Albendazole Administration and Iron-Folic Acid Supplementation on Hemoglobin Level in Primary Schoolchildren with Soil-transmitted Helminth Infections
Authors: Wijaya Willhans , Pasaribu Ayodhia Pitaloka , Suteno Erwin , Husin Nirmala , Pasaribu Syahril
Published: November 2020

BACKGROUND: Soil-transmitted helminth (STH) infections were the highest infection in children aged 5–15 years old. They lead to iron deficiency anemia and folic acid deficiency. One of the strategies to treat the issues is anthelmintic administration with iron-folic acid supplementation.
AIM: This study aims to evaluate the effectiveness of single-dose albendazole and albendazole with iron-folic acid supplementation on hemoglobin (Hb) levels in children with STHs.
METHODS: This was an open-label randomized clinical trial conducted in Batubara Regency from September to November 2018. Subjects were primary schoolchildren with STH infections. They were grouped into albendazole and albendazole with iron-folic acid supplementation groups. The data were analyzed by independent t-test and Mann–Whitney U-test.
RESULTS: From 139 children, 72 children received albendazole single dose and 67 children received albendazole with 30 mg iron and 250 μg folic acid weekly for 3 months. The median of baseline hemoglobin level was 12.2 gr/dL, whereas after intervention was 12.7 gr/dL. The hemoglobin level increases did not differ significantly between the two groups (p > 0.05). However, clinical improvement was observed.
CONCLUSION: Iron-folic acid supplementation in addition to albendazole did not show any benefit for primary schoolchildren with STH infection in Batubara Regency, North Sumatera, Indonesia.
Analysis of Clinicopathologic Factors and KRAS Gene Mutation in Epithelial Ovarian Cancer Outcomes
Authors: Friadi Andi , Harahap Wirsma Arif , Amir Arni , Andrijono Andri
Published: November 2020

BACKGROUND: Raise of ovarian cancer mortality is caused by high ovarian cancer recurrence. This is related to many prognostic factors. Kirsten-rat sarcoma virus oncogene (KRAS) is a proto-oncogene that regulates proliferation, growth and cell motility. The controversy of some experts regarding KRAS mutations in the prognosis of ovarian cancer makes it interesting to analyze.
AIM: The aim of this study is to clarify whether the clinicopathologic factors and KRAS gene mutation affect the recurrence of patients with ovarian cancer in Indonesia.
METHODS: The authors conducted a retrospective cohort study. Clinicopathological factors and prognoses were obtained for 205 patients who were histopathologically diagnosed with epithelial ovarian cancer or ovarian borderline malignant tumor, operated from June 2015 to January 2019 at Dr. M. Djamil General Hospital. We gathered 80 patients who were diagnosed with epithelial ovarian cancer since June 2015 until January 2019. These cases were analyzed after 2-year follow-up or recurrence occurred. Survival rate was determined using the Kaplan–Meier method and examined by Log rank test. All analyses were performed using STATA ver. 12.0, with p < 0.05 considered to be significant.
RESULTS: Among KRAS mutation group, the 2-year disease free survival rate (2y-DFS) was 31.56% and 47.58% in non-mutation group with significant differences between mutation and non-mutation (p = 0.02). There was a significant difference between early stage ovarian cancer with non-mutation group and advanced stages ovarian cancer with mutation group (p = 0.00). Among combination staging with mutation group, the 2y-DFS was 85.79% in early stage ovarian cancer with non-mutation, 44.44% in early stage with mutation, 10.65% in advanced stage with non-mutation, and 20.00% in advanced stage with mutation.
CONCLUSION: The results suggest that staging and KRAS mutation are the most influence prognostic factors for epithelial ovarian cancer. There was a discrepancy of prognosis by staging and mutation between early stage with non-mutation and advanced stage with KRAS mutation.
Predictor of Successful DJ Stent Insertion in Advanced Cervical Cancer
Authors: Santosa Kadek Budi , Prawira Made Moniaga , Pramana Ida Bagus Putra , Tirtayasa Pande Made Wisnu , Yudiana Wayan , Duarsa Gede Wirya Kusuma , Oka Anak Agung Gede
Published: November 2020

BACKGROUND: Metastatic cervical cancer in the ureter may lead to obstructive uropathy due to mechanical ureteral blockage. The insertion of a double J (DJ) stent is a urinary diversion option that can be offered to the patients, but it becomes challenging due to the high rate of failures.
AIM: The aim of the study was to determine the factors that predict the success of DJ stent insertion in obstructive uropathy due to advanced cervical cancer.
MATERIALS AND METHODS: The patients studied were those with obstructive uropathy due to advanced cervical cancer from 2017 to 2020 in Sanglah General Hospital. The research subjects were divided into two groups: First were the samples of successful DJ stent insertions and the second were those that failed. In the analysis, the Chi-square tests were used for categorical data, while the independent t-tests were used for normally distributed data. Logistic regression analyses which involved both the univariate and multivariate were conducted to determine the factors that aided the success of DJ stent insertions.
RESULTS: Retrograde stent insertion of DJ stents was conducted on 100 patients. Successful insertions were found in 57 patients (57%), while those that failed were observed in 43 subjects (43%). The results of multivariate regression analyses showed that low-grade hydronephrosis (odd ratios [OR] = 62.024; p = 0.000; confidence interval [CI] = 9.485–405.596), normal albumin levels (OR = 5.856; p = 0.018; CI = 1.359–25.243), lower Federation of Gynecology and Obstetrics (FIGO) staging (OR = 14.985; p = 0.007; CI = 2.108–106.536), and a history of radiotherapy (OR = 8.758; p = 0.005; CI = 1.943–39.477) were the significant factors for predicting the success of DJ stent insertions.
CONCLUSION: Low-grade hydronephrosis, normal albumin levels, lower FIGO staging, and a history of radiotherapy are the strong factors for predicting the success of DJ stent insertions in obstructive uropathy due to advanced cervical cancer.
The Relation between Lipid Profile and Glycemic Control in Type 2 Diabetes Mellitus Patients in North Sumatera, Indonesia
Authors: Rusdiana Rusdiana , Widjaja Sry Suryani , Savira Maya
Published: November 2020

BACKGROUND: The global prevalence of type 2 diabetes mellitus (DM), a chronic metabolic disorder, has been steadily increasing. Increasing blood sugar levels (BSL) are reliably measured by glycated hemoglobin (HbA1c).
AIM: The aim of this research is to observe the relation between lipid profile with glycemic control at uncontrolled and controlled type 2 DM, early detection of abnormalities in the lipid profile can minimize cardiovascular complication risk in patients with type 2 DM.
METHODS: Collecting medical data record, for example, blood pressure, height and body mass index, duration of disease, family history, and medicine treatment. Laboratory examination such as BSL, HbA1c levels, and lipid profile such as cholesterol, low-density lipoprotein, high-density lipoprotein, and triglycerides (TGs) was evaluated. The study was conducted by implementing cross-sectional methods, among 112 patients with type 2 DM who were admitted from various primary health-care centers in Medan city and the surrounding areas in North Sumatera. The sample criteria are type 2 DM’ patients and both genders. The exclusion criteria of the samples are those with type 1 DM and critical disease.
RESULTS: There is a difference between the average lipid profile level (high-density lipoprotein and TG) in controlled and uncontrolled type 2 DM. Furthermore, there is also a difference between the average HbA1c value in controlled type 2 DM and uncontrolled type 2 DM (p<0.005).
CONCLUSION: This study showed a difference in lipid profile (high-density lipoprotein and TG) and HbA1c between uncontrolled and controlled type 2 DM. Therefore, type 2 DM patients were recommended to undergo periodical glycemic and lipid profile examination control to prevent cardiovascular disease complication.
Alpha Glutathione S-transferase – A Potential Biomarker for Intestinal Epithelial Damage in Infants with Acute Gastroenteritis
Authors: Dimitrovska-Ivanova Marija , Zisovska Elizabeta
Published: November 2020

BACKGROUND: Acute gastroenteritis is a leading cause of morbidity and mortality in children under 3 years of age worldwide and mostly can be dangerous in the first 12 months of life especially in infants who are not exclusively breastfed. Intestinal pathogens cause enterocyte infection which leads to cell death, lumen extrusion, and intestinal villous atrophy.
AIM: The aim of this study was to assess whether alpha glutathione S-transferase (α-GST) can be a biomarker for early intestinal epithelial damage in infants with acute gastroenteritis and the degree of correlation of its serum values with the degree of intestinal epithelial damage associated with infant nutrition.
MATERIALS AND METHODS: A total of 23 infants with acute gastroenteritis divided into two groups based on the feeding patterns (type of milk) were included in the study. The values of α-GST in serum between exclusively breastfed and non-exclusively breastfed infants were examined.
RESULTS: It was found a statistically significant association between group affiliation and the α-GST levels in serum between the first and the second group (p = 0.002260). It was revealed that Rotavirus can cause erosion of the intestinal epithelium through the positive values of α-GST in Rotavirus positive cases.
CONCLUSION: In this study, it was found that α-GST is a biomarker for early intestinal epithelial damage in infants primarily with Rotavirus acute gastroenteritis. α-GST serum values were significantly lower in infants who were exclusively breastfed compared with infants who were not exclusively breastfed.
Effects of Pleuran (β-glucan from Pleurotus ostreatus) Supplementation on Incidence and Duration of Bronchiectasis Exacerbations
Authors: Minov Jordan , Stoleski Sasho , Karadzinska-Bislimovska Jovanka , Petrova Tatjana , Vasilevska Kristin , Mijakoski Dragan , Jesenak Milos
Published: November 2020

BACKGROUND: Patients with non-cystic fibrosis bronchiectasis (BE) have frequent exacerbations that are causes of significant morbidity and sometimes mortality, and which it is desirable to prevent.
AIM: We aimed to assess the effects of pleuran on the incidence and duration of exacerbations in patients with BE.
METHODS: A prospective, observational, open-label, and active-controlled study was realized as a comparison of the frequency and duration of exacerbations between a group of patients with BE (30 patients, 14 males and 16 females, aged 44–72 years) who received a combination supplement containing pleuran 100 mg, Vitamin C 60 mg and zinc 5 mg over a 3-month period and a group of patients with BE (31 patients, 15 males and 16 females, aged 45–74 years) treated over a 3-month period with a combination supplement containing Vitamin C 60 mg and zinc 5 mg.
RESULTS: Over the study period, altogether 46 exacerbations were documented (19 in the patients receiving pleuran and 27 in the patients who did not receive pleuran), nine of which required hospital treatment (four in the patients receiving pleuran [21.5%] and five in the patients who did not receive pleuran [18.6%]). The mean number of exacerbations over the study period was significantly lower in the patients receiving pleuran (0.6 ± 0.4) as compared to the mean number in the patients who did not receive pleuran (0.8 ± 0.3) (p = 0.0297). The mean duration of exacerbations, expressed in days, needed for cure or clinical improvement in the patients receiving pleuran (11.2 ± 1.7 days) was significantly shorter than that of exacerbations in the patients who did not receive pleuran (12.4 ± 1.3 days) (p = 0.0029). We found significantly lower incidence and significantly shorter duration of exacerbations in the patients with BE who received pleuran as compared to their incidence and duration in the patients with BE who did not receive pleuran.
CONCLUSION: Our findings indicated a need for further investigations in this domain to define the possible role of pleuran in the prevention of BE exacerbations.
Computerized Tomography Score for the Assessment of Multiple Organ Failure and Determining Severity of Pancreatitis: Key Principles for the Assessment of Affected Organs
Authors: Ermekova Madina , Aliyakparov Makash , Shakeev Kayrat , Zholdybaeva Gulfayruz
Published: November 2020

BACKGROUND: Pancreatitis severity is an important death rate indicator that plays a crucial role in deciding on proper handling of patients at their initial admission, when making a decision on patient’s transfer to the intensive care unit. Many studies point out a direct relation between death rate and the number of affected organs. In view of that, looking for new criteria for assessment of multiple organ failure is still useful in clinical practice. Assessment of multiple organ failure with patients undergoing treatment in the intensive care unit is carried out with the use of various integrated indicators based both on clinical laboratory assessment of patient’s condition, and on data obtained with the help of advanced imaging methods. However, many researchers point out that the facilities of diagnostic radiology, including in particular computerized tomography (CT), are not used to the full extent.
AIM: We proposed expanding functionality of abdominal CT examination by means of pancreatitis severity assessment that takes into account changes in the pancreas and in addition enables assessing multiple organ failure with examined patients. We identified the organs and systems whose changes need to be monitored through CT imaging to be able to assess multiple organ failure in the patients with pancreatitis.
METHODS: Out of 314 patients, 100 patients were selected diagnosed with pancreatitis confirmed by changes demonstrated by the laboratory test results. Of those, 24 patients (24.0%) revealed presence of multiple organ failure (maximum of 5 organ systems), 46 patients revealed a single organ failure.
RESULTS: Development of early organ failure accompanied 82% of cases of severe pancreatitis and considerably aggravated predicted outcome and course of severe AP. Among them, 30 patients had pancreatitis without changes of the vital organs and 70 patients had dysfunctions of the vital organs, suffered from organ or multiple organ failure, and received treatment in the surgery unit and the intensive care unit of the Department of Surgical Conditions of Karaganda Medical University. In view of CT results, we assessed a relation between multiple organ failure and specific failure of a single organ and necrosis and death rate. We analyzed a relation between organ failure and degree of the pancreas necrosis.
CONCLUSION: Identified changes enabled us to create a CT score for the assessment of pancreatitis severity that can be used not only for identification but also for the prediction of organ failure at an early stage of pancreatitis with high accuracy as compared against conventional CT systems for the assessment of patients’ condition. It can also be used to differentiate extent organ dysfunction and the number of affected organs.
Urgent Endovascular Treatment of Iliac Artery Pseudoaneurysm in Patient with Ehlers-Danlos Syndrome: A Case Report
Authors: Gjoreski Aleksandar , Jovanoska Ivona , Dungevski Gjorgi , Lazovski Nikola , Lazareska Menka
Published: November 2020

BACKGROUND: Ehlers-Danlos syndrome (EDS) type IV is a heritable disorder of connective tissue that is mainly associated with vascular maladies such as aneurysms, pseudoaneurysms, and dissections with or without spontaneous rupture. Historically, vascular complications in EDS IV have been treated conservatively whenever possible, due to the high morbidity and mortality after vascular interventions, whether open or endovascular. We present a case of a ruptured pseudoaneurysm of the right common iliac artery in a 18-year-old male, who was successfully treated by endovascular approach and later diagnosed with EDS type IV.
CASE PRESENTATION: A 18-year-old male patient was admitted in ER with sharp pain in the right hypogastrium, hypotensive and with reduced blood parameters. Multiphasic modern computed tomography (MDCT) scan of abdomen and pelvis revealed massive ride sided pelvic and retroperitoneal hematoma. The presence of pseudoaneurysms on both common iliac arteries (CIA) was detected, with small ulcer on the right side and a focal dissection on the left side. An urgent endovascular repair of the ruptured pseudoaneurysm on the right CIA with covered stent was performed. Patient’s laboratory parameters and clinical status improved significantly within the next few days.
CONCLUSIONS: Vascular repair in EDS-IV patients carries significant risk and should be indicated very carefully. Endovascular treatment for these patients is feasible and should be considered as an alternative to open surgery in some challenging cases as this one.
L’application du droit à l’hébergement comme enjeu sanitaire et économique : étude sociologique de l’accès à l’hébergement à Marseille
Authors: Allaria Camille
Published: November 2020

L’accueil inconditionnel dans les centres d’hébergement pour les personnes sans abri ainsi que la continuité de leur prise en charge dans des structures adaptées constituent deux éléments essentiels du Code de l’action sociale et des familles en matière de protection des personnes sans logement. Pourtant, il arrive que des consignes officieuses, émanant des services décentralisés de l’État, viennent faire obstacle à l’application du droit inconditionnel à l’hébergement. Cet article analyse la façon dont les obstacles rencontrés par les travailleurs sociaux dans l’application du droit saturent artificiellement les dispositifs d’hébergement des populations les plus précaires et la façon dont ils y font face en pratique.
Les jeux dangereux au collège, une approche spatiale
Authors: Hebert Thibaut , Vigne Mickaël , Dugas Éric
Published: November 2020

L’objet de cet article est de questionner l’aménagement des espaces scolaires dans une quête de prévention des conduites à risque tels que les jeux dangereux. Sur les 10080 collégiens interrogés, nous avons analysé les réponses des 2850 élèves ayant déclaré avoir pratiqué au moins une fois un jeu dangereux. Les résultats révèlent en premier lieu que la cour de récréation, malgré la présence des adultes, fait figure de terrain idéal à la pratique des jeux dangereux. En second lieu, les espaces interstitiels se distinguent par une surreprésentation des jeux à valence agressive. Cette étude confirme alors que le type d’architecture valorisé dans les collèges français conjugué à des aménagements succincts favorisent certains types de jeu.
« La prostitution, ça ne tue pas ! » Projets d’ascension sociale familiale dans le contexte de la traite sexuelle (Nigeria-Europe)
Authors: Apard Élodie , Diagboya Precious , Simoni Vanessa
Published: November 2020

La majorité des jeunes femmes africaines en situation de prostitution aujourd’hui dans les grandes villes européennes sont originaires de l’État d’Edo, au sud du Nigeria, une région où la traite est devenue un modèle économique à part entière. Malgré le jugement moral et la stigmatisation dont souffrent les prostituées au Nigeria, l’envoi d’une fille en Europe représente une opportunité que de nombreuses familles décident de saisir, misant sur les retombées financières potentielles qui permettraient une ascension sociale collective. La prostitution vue comme un projet migratoire familial au Nigeria permet d’éclairer le rôle joué par les parents dans les mécanismes qui rendent possible, voire renforcent, l’exploitation sexuelle des filles en Europe.