bluuebunny/crossref_metadata_2025 huggingface dataset:
Sociodemographic, Clinical and Geriatric Characteristics Associated with Poor Atrial Fibrillation-Related Quality of Life in Older Adults with Atrial Fibrillation: A cross-sectional study
Authors: Pierre-Louis Isabelle C. , Saczynski Jane S. , Lopez-Pintado Sara , Waring Molly E. , Abu Hawa O. , Goldberg Robert J. , Kiefe Catarina I. , Helm Robert , McManus David D. , Bamgbade Benita A.
Published: October 2022

Background.
Though previous research has assessed sociodemographic, clinical and geriatric factors associated with poor atrial fibrillation-related quality of life (AFQoL); few studies have examined a battery of geriatric factors. The objective of this study is to describe eight geriatric factors, as well as the sociodemographic and clinical factors, associated with poor AFQoL in older adults with atrial fibrillation.
Methods.
Cross-sectional analysis of baseline data from a prospective cohort study of participants aged 65 + with high stroke risk and atrial fibrillation. AFQoL was measured using the validated Atrial Fibrillation Effect on Quality of Life (score 0-100) and categorized as poor (< 80) or good (80–100). Chi-square and t-tests were used to evaluate differences in factors across poor AFQoL and significant characteristics (p < 0.05) were entered into a multivariate logistic regression models to identify variables independently related to poor AFQoL.
Results.
Of 1,244 participants (mean age 75.5 [standard deviations: 7.1] years, 49% female), 42% reported poor AFQoL. Having a fall in the past 6 months, pre/frail & frailty, depression, anxiety, social isolation, vision impairment, oral anticoagulant therapy, chronic obstructive pulmonary disease and taking more than 12 medications daily were associated with higher odds of poor AFQoL. Being married and having a college education were associated with a lower odds of poor AFQoL.
Conclusions.
More than 4 out 10 older adults with AF reported poor AFQoL. Geriatric characteristics significantly associated with higher odds of reporting poor AFQoL include falls in the past 6 months, frailty, elevated depressive symptoms, elevated symptoms of anxiety, social isolation and vision impairment. Findings from this study may help clinicians screen for patients with poor AFQoL who could benefit from tailored management to ensure the delivery of patient-centered care and improved well-being among older adults with atrial fibrillation.
The Impact of Corporate Governance and Audit Quality on the Investment Decision
Authors: Shazly Mo’men A. , AbdElAlim Khaled , Mortaky Abanob Nashat
Published: October 2022

The main purpose of this research is to study the impact of corporate governance and audit quality on the investment decision. In order to achieve this objective, the research collected literature review about previous variables. This research used survey method on the construction sector in Egypt. They are 97 completed questionnaires. Data was analyzed and hypotheses tested by using Statistical Package for the Social Sciences (SPSS). The research found that there’s significant positive impact of corporate governance on the audit quality and investment decision which means investors will depend on the corporate governance when they make their investment decision. In addition, investors will depend on the audit quality (the ability of an auditor to detect a breach (auditor competence) and the willingness to report such a breach (auditor independence) when they make their investment decision.
Peripartum Ruptured Uterine Angioleiomyoma
Authors: Mohamed Nora , Almasalma Ayman
Published: October 2022

Uterine angioleiomyoma is a rare entity. Angioleiomyoma is a benign vascular tumor that originates fromthe blood vessels. Although exceptionally they can be found in the uterus, they are commonly reportedin the lower extremity. Preoperative diagnosis is tricky. We are publishing this case to highlight uterinecontractions as a possible cause of the peripartum rupture.
The patient was in her fourth pregnancy, with a history of three vaginal deliveries. She presented to theemergency department in our hospital with labor pain, at 39 weeks of gestation, and was admitted to thelabor unit in active labor. She had an uneventful vaginal delivery with a good neonatal outcome. Afterdelivery, the patient complained of abdominal pain, shoulder tip pain, and abdominal distention.
Examination revealed a tender mass felt on the left side of the uterus up to the left hypochondriac region, contracted  uterus, and normal lochia. A CT (computed tomography) scan was carried out and was remarkable for a left-sided, mixed-density, abdominopelvic lesion, measuring 18×12×9 cm, and a moderate amount of hemoperitoneum. Intraoperatively there was 1 liter of free blood, ruptured left-sided, subserous myoma connected to a 20×15 cm hematoma. A myomectomy was carried out. Histopathology reported an angioleiomyoma with symplastic-type cells.
Although infrequent, complicated angioleomyoma should be suspected in the differential diagnosis ofabdominopelvic hematoma in patients with uterine fibroids
Duty of Disclosure for Insurance Contracts: A Comparative Note of the United Kingdom and Indonesia
Authors:   Erasmus University Rotterdam, The Netherlands, Yuniarti Shanty Ika
Published: October 2022

Duty of disclosure is one of the most essential aspects of an insurance contract. Its role in an insurance contract is to avoid fraud and misinterpretations. A person seeking insurance must act in good faith, and good faith requires to disclose every material fact known, related to the risk. It begins with the proposer for the insurance policy that is obliged to disclose all information to the insurer. However, there is a possibility either the insured or insurer done a breach of duty of disclosure. Breach of duty of disclosure includes Non-Disclosure and Misrepresentation. Breach of duty of disclosure also possible to happen in the Pre-Contractual and Post-Contractual Stage in an insurance contract due to either a deliberate, reckless, or innocent breach. The duty of disclosure in each country might be different depends on its jurisdiction, for example, the United Kingdom as a common law country and Indonesia as a civil law country.
Employment Layoff Policy During Covid-19 Pandemic (Legal Comparative Analysis Based on Indonesia and Singapore Law)
Authors:   Universitas Indonesia, Jl. Prof. Mr Djokosoetono, Pondok Cina, Beji, Depok City, West Java 16424, Prikasetya Gratianus
Published: October 2022

The Covid-19 pandemic has made Employment Layoffs in Industrial Relation become unavoidable both in developing and developed countries. Throughout 2020, the number of layoffs, which can be seen from the unemployment rate in these two countries, has increased. Employment Layoff in Indonesia is subject to the provisions of Law No. 13 of 2003 concerning Manpower Law as partially amended by Law No. 11 of 2020 concerning Job Creation, while Singapore regulates it in the Employment Act of Singapore Chapter 91. Government intervention in implementing the Layoff Policy tend to be greater in Indonesia than in Singapore. This is the impact of the Corporatist Industrial Relations Model system used in Indonesia, while Singapore uses the Contractualist Industrial Relations Model system which relies more on the industrial relations settlement mechanism to the parties. This article was prepared by using Legal Research Methods, especially comparative law between Indonesian Law and Singapore Law.
Does intermittent supply result in hydraulic transients? Mixed evidence from two systems
Authors: Erickson John J. , Nelson Kara L. , Meyer David D. J.
Published: October 2022

Pressure transients can cause severe damage in continuous water supply pipe networks, but little is known about pressure transients in intermittent networks. Published examples of high-frequency pressure monitoring in intermittent networks are lacking. Intermittent supply can be caused by poor network condition and is associated with delivering less water, less frequently, and with poorer quality than continuous supply. Given the frequency with which intermittent systems drain, fill, and change supply regimes, pressure transients have been hypothesized to be common and to be one mechanism by which intermittent supply further degrades network condition. We present supply start-up data from two very different intermittent systems: a low-pressure, intermittent network in Delhi, India, and a higher-pressure intermittent network in Arraiján, Panama. Across monitoring locations at both sites, we did not detect substantial pressure transients due to pipe filling. In Arraiján, pump start-ups, pump shutdowns, and pipe bursts were associated with potentially problematic transients. We conclude that pipe filling in intermittent supply does not always result in concerning pressure transients. The largest risks to pipe conditions we observed were due to pumping changes in close succession; hence, we recommend that utilities operating intermittent (and continuous) systems leave adequate dissipation time between changes in pump operation.
Dual Inhibitors Of Prostaglandin And Leukotriene Biosynthesis
Authors: Dyer Richard D. , Connor David T.
Published: October 2022

One of the most promising approaches for minimizing the side effects of nonsteroidal antiinflammatory drugs (NSAIDs) is to concurrently inhibit the activities of both 5-lipoxygenase (5-LO) and cyclooxygenase (CO). Many such dual inhibitors of prostaglandin (PG) and leukotriene (LT) production in vitro have been described but, despite intense pharmaceutical research efforts, the translation of this in vitro activity
into in vivo efficacy has proven difficult. Chemical modification of one series of inhibitors, the 2,6-di-tert­ butylphenols, has provided a variety of dual inhibitors with antiinflammatory efficacy and superior gastrointestinal (GI) safety. Whereas optimization of the di-t-butylphenols for in vitro activity, inhibitory specificity, oral availability and antiinflammatory efficacy resulted in the identification of Cl-1004 and other clincal candidates, optimization of other chemical series typically resulted in dual inhibitors with potent in vitro effects but little in vivo activity. The development of several dual inhibitors, including tepoxalin, tebufelone and CI-986, has been limited by drug metabolism issues. Translation of the attractive preclinical antiinflammatory and safety profile of dual inhibitors to the clinical arena awaits the completion of thorough clinical studies, such as those currently underway with CI-1004.
Isolation and Bioactivities of Limonoids from Meliaceae Family: A Review
Authors: Hieu Tran Trung , Thuy Phan Thi , Duc Dau Xuan
Published: October 2022

Limonoids are the most representative metabolites present in the order Rutales, which includes the families Rutaceae, Meliaceae and Cneoraceae. They are tetranortriterpenoids with a 4,4,8-trimethyl-17-furanylsteroidal skeleton, containing several oxygenated functions. The Meliaceae family consists of 50 genera with more than 1400 species distributed in tropical and subtropical regions worldwide. Plants of this family are found to be rich in limonoids. Limonoids from Meliaceae family exhibit a diverse range of bioactivities cytotoxic, antioxidant, anti-inflammatory, antimicrobial, antimalarial, and antifeedant, activities and some of them have been commercially used for different purposes. Numerous studies on limonoids from Meliaceae family and their bioactivities have been reported recently. This review covers the isolation and structure determination of limonoids reported during 2012–2022. 1172 novel limonoids in 118 papers have been summarized. Furthermore, important biological activities of these limonoids have also been outlined. This review can provide useful information for medicinal and pesticidal chemistry and phytochemistry researchers who are interested in the chemistry and biology of limonoids.
Demystifying Bacteriocins of Human Microbiota by Genome Guided Prospects:
An Impetus to Rekindle the Antimicrobial Research
Authors: Thomas Sabu , Suryaletha Karthika , Savithri Akhila Velappan , Nayar Seema A. , Asokan Sijo , Rajeswary Divya
Published: October 2022

The human microbiome is a reservoir of potential bacteriocins that can counteract with the multidrug resistant bacterial pathogens. Unlike antibiotics, bacteriocins selectively inhibit a spectrum of competent bacteria and are said to safeguard gut commensals, reducing the chance of dysbiosis. Bacteriocinogenic probiotics or bacteriocins of human origin will be more pertinent in human physiological conditions for therapeutic applications to act against invading pathogens. Recent advancement in the omics approach enables the mining of diverse and novel bacteriocins by identifying biosynthetic gene clusters from the human microbial genome, pangenome or shotgun metagenome, which is a breakthrough in the discovery line of novel bacteriocins. This review summarizes the most recent trends and therapeutic potential of bacteriocins of human microbial origin, and the advancement in the in silico algorithms and databases in the discovery of novel bacteriocin, and how to bridge the gap between the discovery of bacteriocin genes from big datasets and their in vitro production. Besides, the later part of the review discussed the various impediments in their clinical applications and possible solution to bring them in the frontline therapeutics to control infections, thereby meeting the challenges of global antimicrobial resistance.
Artificial Intelligence in De novo Drug Design: Are We Still There?
Authors: Kumar Rajnish , Sharma Anju , Alexiou Athanasios , Ashraf Ghulam Md
Published: October 2022

Background:

The artificial intelligence (AI)-assisted design of drug candidates with novel structures and desired properties has received significant attention in the recent past, so relat-ed areas of forward prediction that aim to discover chemical matters worth synthesizing and further experimental investigation.

Objective:

The purpose behind developing AI-driven models is to explore the broader chemical space and suggest new drug candidate scaffolds with promising therapeutic value. Moreover, it is anticipated that such AI-based models may not only significantly reduce the cost and time but also decrease the attrition rate of drug candidates that fail to reach the desirable endpoints at the final stages of drug development. In an attempt to develop AI-based models for de novo drug design, numerous methods have been proposed by various study groups by applying machine learning and deep learning algorithms to chemical datasets. However, there are many challenges in obtaining ac-curate predictions, and real breakthroughs in de novo drug design are still scarce.

Method:

In this review, we explore the recent trends in developing AI-based models for de novo drug design to assess the current status, challenges, and opportunities in the field.

Conclusion:

The consistently improved AI algorithms and the abundance of curated training chem-ical data indicate that AI-based de novo drug design should perform better than the current models. Improvements in the performance are warranted to obtain better outcomes in the form of potential drug candidates, which can perform well in in vivo conditions, especially in the case of more com-plex diseases.
Recent Advances in the Development of Nitrogen-containing Heterocyclic
Anti-alzheimer’s Agents
Authors: Chawla Pooja A. , Kumar Ankur , Nehra Bhupender , Singh Dilpreet , Kumar Dileep
Published: October 2022

Alzheimer’s disease (AD) remains one of the major neurodegenerative diseases over-whelming the world today. Alzheimer’s is the most complicated as well as perplexing disease en-countering serious global health issues. Alzheimer’s disease is well characterized as a general cause of dementia, which includes issues with memory, language, problem-solving, and other cognitive behaviours, such as disabled perception as well as trouble talking due to degeneration of neurons. According to the latest report, there are about 44 million individuals who are currently suffering from dementia, which has been prophesied to extensively grow up to 3-fold by 2050. Alzheimer’s disease is usually triggered by numerous associated factors, including depleted amount of acetyl-choline (ACh), excessive aggregation of β-amyloid peptide (Aβ), tau hyperphosphorylation with neurofibrillary tangle formation as well as deposition of feeble plaques in a specific portion of the brain (hippocampus and cortex). Besides these superior factors, sometimes AD can be induced or become complex due to several reasons, such as inflammatory mechanisms and oxidative stress. Furthermore, heterocyclic scaffolds comprise assorted implications in the drug design and devel-opment process. Heterocycles have also elicited their evolving role as core scaffolds in numerous synthetic derivatives with potent anti-Alzheimer’s potential. There are only limited drugs that are present in the market to treat Alzheimer’s disease in an efficacious manner. Hence, the identifica-tion, design, and development of new anti-Alzheimer’s drugs are an emerging need to eradicate complex clinical indications associated with Alzheimer’s disease. This review aims to summarize various recent advancements in the medicinal chemistry of heterocycle-based compounds with the following objectives: (1) to represent inclusive literature reports describing the anti-Alzheimer’s po-tential of heterocyclic derivatives; (2) to cast light on recent advancements in the medicinal chemis-try of heterocyclic compounds endowed with therapeutic potential against Alzheimer’s disease; (3) to summarize the comprehensive correlation of structure-activity relationship (SAR) with the phar-macological responses, including in silico and mechanistic studies to provide ideas related to design and development of lead molecules.
Relationship Between Gut Bacteria and Levodopa Metabolism
Authors: Xu Kaifei , Sheng Shuo , Zhang Feng
Published: October 2022

Parkinson’s disease (PD) is one of the most common neurodegenerative diseases,
characterized by the reduction of dopamine neurons in the substantia nigra. Levodopa,
as a dopamine supplement, is the gold-standard therapeutic drug for PD. The
metabolism of levodopa in the periphery not only decreases its bioavailability but also
affects its efficacy. Thus, it is necessary to investigate how levodopa is metabolized.
A growing number of studies have shown that intestinal bacteria, such as
Enterococcus faecalis, Eggerthella lenta and Clostridium sporogenes, could
metabolize levodopa in different ways. In addition, several pathways to reduce
levodopa metabolism by gut microbiota were confirmed to improve levodopa
efficacy. These pathways include aromatic amino acid decarboxylase (AADC)
inhibitors, antibiotics, pH and (S)-α-fluoromethyltyrosine (AFMT). In this review, we
have summarized the metabolic process of levodopa by intestinal bacteria and
analyzed potential approaches to reduce the metabolism of levodopa by gut
microbiota, thus improving the efficacy of levodopa.
Alkaloids as Antimalarial Compounds: A Review of Recent Studies
Authors: Saufi Nor Asma Umais Mohammad , Hatta Ummu Umairah M. , Rashid Fatin Nur Ain Abdul , Mohammat Mohd Fazli
Published: October 2022

Malaria is a parasitic infection caused by Plasmodium parasites that are transmitted to
humans through the bite of infected Anopheles mosquitoes. Malaria continues to contribute unacceptably
high rates of sickness and death. Natural product compounds have long been recognized as
one of valuable natural remedy resources with promising structural motif pools for the development
of first-line drugs. Resistance to conventional treatments such as chloroquine, mefloquine, and artemisinin-
based combination therapy (ACT) by the causal agent, the Plasmodium parasite, is a major
concern in malaria treatment and prevention globally. Given the parasites' resistance to several current
treatment regimens, innovative antimalarial chemotherapeutic medicines derived from tetramic
acid alkaloids are desperately needed. In this review, new and old antimalarial alkaloids identified
and reported recently from 2017 to 2021 are presented. Several compounds with promising antimalarial
activity are identified from several subclasses of alkaloids. It is hoped that this review report
will inspire future research into the compounds' toxicity and in vivo efficacy, to exploit this intriguing
compound as antimalarial drugs.
Bacteriophages Against Pathogenic Bacteria: In Medicine and Agriculture
Authors: Anaghez Zahra Zaer , Rasizadeh Reyhaneh , Aghbash Parisa Shiri , Feizi Hadi , Khakvar Reza , Baghi Hossein Bannazadeh
Published: October 2022

Abstrat:

One of the critical issues that humans worldwide are facing is bacterial infections. Antibiotics
were developed as bactericidal agents to avoid the negative consequences of bacterial infections,
and they were initially highly efficient against bacteria. However, we face a phenomenon
called antibiotic resistance by misusing these chemical antibiotics in this era. In other words, bacteria
began to acquire resistance to common antibiotics, and resistance means going back to a time
before antibiotics. As it is a significant threat to human health and causes increased mortality, there
is a rising demand for novel alternative therapies. An alternate method is to use bacteriophages
(phages) as a therapeutic agent against bacterial infections in medicine and agriculture. Phages are
viruses capable of infecting pathogenic bacteria, which can cause serious diseases. They do not
affect the human microbiota; most only infect certain bacteria. Some research has been done on
using phages as a treatment, and more experiments today. For instance, eye infections caused by
methicillin-resistant Staphylococcus aureus (MRSA) can be treated by eye drops containing appropriate
phages. In this regard, significant progress has been made in phage therapy. This review will
discuss the current state of phage therapy, clinical breakthroughs, its superiorities and drawbacks,
and the future perspectives of phage applications.
Prediction of Cancer Treatment Using Advancements in Machine
Learning
Authors: Singh Arun Kumar , Ling Jingjing , Malviya Rishabha
Published: October 2022

Many cancer patients die due to their treatment failing because of their disease's resistance
to chemotherapy and other forms of radiation therapy. Resistance may develop at any
stage of therapy, even at the beginning. Several factors influence current therapy, including
the type of cancer and the existence of genetic abnormalities. The response to treatment
is not always predicted by the existence of a genetic mutation and might vary for various
cancer subtypes. It is clear that cancer patients must be assigned a particular treatment or
combination of drugs based on prediction models. Preliminary studies utilizing artificial
intelligence-based prediction models have shown promising results. Building therapeutically
useful models is still difficult despite enormous increases in computer capacity due to the lack
of adequate clinically important pharmacogenomics data. Machine learning is the most widely
used branch of artificial intelligence. Here, we review the current state in the area of using
machine learning to predict treatment response. In addition, examples of machine learning
algorithms being employed in clinical practice are offered.
Influence of SGLT2 Inhibitors in Remodeling, Substrate and Ion Metabolism
of Myocardium to Prevent Cardiovascular Risks: Recent Work and
Advancement
Authors: Johri Nishant , Matreja Prithpal Sing , John Davis , Dutta Shubham , Parida Ashok Kumar , Sarma Susanta Nath
Published: October 2022

Sodium-glucose cotransporter 2 (SGLT2) inhibitors are a new class of drugs that lower
blood glucose levels while decreasing blood pressure, volume loss, and weight loss. SGLT2
inhibitors were studied to determine their effectiveness in treating cardiovascular disease and
their side effects. Study outcomes related to cardiovascular and metabolic outcomes were examined
in patients on SGLT2 inhibitors by searching PubMed, Embase, Cochrane, and SCOPUS.
Articles related to clinical trials, reviews, and meta-analyses were considered. A review of
SGLT2 inhibitors' mechanisms of action in preventing cardiovascular (CVS) disease progression
was described. We then reviewed the possible effects of SGLT2 inhibitors on CVS dysfunction
development, composition, and stability. In the following, we discussed the impact of SGLT2 inhibitors
on CVD events, such as ischemic strokes and myocardial infarctions, and their role in
treating congestive heart failure and cardiovascular mortality.
Evaluation of Cytotoxic and Neuropharmacological Activity of Methanolic
Extract of Solanum capsicoides Leaves
Authors: Nobee Md. Mahamodun , Chowdhury Anita Rani , Rodru Fariya Islam , Ahmed Jamiuddin , Paul Hridoy Kumar , Sarkar Kishore Kumar , Islam Farhana
Published: October 2022

Background:

Solanum capsicoides has medicinal importance due to having numerous
therapeutically active ingredients.

Objective:

The aim of this study was to assess and interpret the cytotoxic and neuropharmacological
activity of the methanolic extract of Solanum capsicoides leaves.

Methods:

The lethality bioassay test on brine shrimp was used to evaluate the cytotoxicity effect of
the methanolic extract of Solanum capsicoides leaves. To evaluate the neuropharmacological activities
of this plant extract, hole board test, hole cross test, open field test and elevated plus-maze test
were used in mice model. All assessments were statistically analysed using one-way ANOVA followed
by Dunnett’s t-test. All of the data were analysed with the help of the SPSS software.

Results:

The test for brine shrimp lethality demonstrated that the LC50 of methanolic extract of Solanum
capsicoides leaves was 55.883 μg/ml, containing potent cytotoxic components. The statistically
significant (*P<0.05, **P<0.05 vs. control) result in hole board test, hole cross test, open field
test, and elevated plus-maze test reveals the CNS depressant and anxiolytic properties in methanolic
extract of Solanum capsicoides leaves.

Conclusion:

Results from our study support that the methanolic extract of Solanum capsicoides might
possess significant cytotoxic characteristics, CNS depressant and anxiolytic effect. However, additional
research is required to pinpoint the precise bioactive chemicals that are responsible for these activities.
ANALYSIS AND COMPARING FORECASTING RESULTS USING TIME SERIES METHOD TO PREDICT SALES DEMAND ON COVID-19 PANDEMIC ERA
Authors:   Industrial Engineering Program, Bhayangkara Jakarta Raya University, Paduloh Paduloh , Ustari Abdul ,   Industrial Engineering Program, Bhayangkara Jakarta Raya University
Published: October 2022

The Covid-19 pandemic has made uncertainty in demand very high; there have been many changes in demand due to changes in the market and people's buying methods. So that forecasting accuracy is significant for every industry, at least the forecast that is closest to the conditions faced by the company so that the company does not lose money due to forecasting errors. Time series is a widely used model for forecasting using past data. This study aims to minimize forecasting errors by analyzing which demand forecasting model is most suitable for demand conditions based on historical data on demand for masterbatch products. The method used in this study is a time series model, which consists of the season naive method, holt exponential smoothing, exponential triple smoothing, and autoregressive integrated moving average (ARIMA). Data processing is done using Rstudio software. The results show that the ARIMA method (2,1,0) (1,1,0) is the best because it has the smallest error rate value with case studies and exact data; the standard error size values used are ME, RMSE, MAE, MPE, MAPE, MASE, and ACF1. This study analyzes forecasting during the Covid-19 pandemic using time series and compares them to find the best results. Then the results of this study can be used as a reference by companies and researchers in determining the model used to make forecasts.
FINAL INVESTMENT DECISION (FID) PROCESS IMPROVEMENT IN OIL & GAS MAJOR CAPITAL PROJECT. CASE STUDY OF PT. VUL’S DECISION-MAKING PROCESS
Authors:   School of Business and Management, Institut Teknologi Bandung, Indonesia, Wibisono Marco , Putro Utomo Sarjono ,   School of Business and Management, Institut Teknologi Bandung, Indonesia
Published: October 2022

Uncertainties from many factors, oil price, production, execution and operational risks, external factors, are issues that impact project profitability. For major capital projects (MCPs), with magnitude of investment well into hundreds of millions or billions of dollars, a robust, structured rational process is required to minimize uncertainties and provide all the required information for a decision maker to make a high-quality, measured decision in continuing with execution of the project. Semi-structured interview for projects with CAPEX valued around $500 million, and above $10 billion were performed; coupled with comparison between appropriation and actual results, and literature reviews to uncover the complexities, experienced issues that happened in the process. Process and bias analysis were performed to provide solution. Reviews were made on Decision Executive (DE)/Decision Review Board (DRB) effectiveness, market price intelligence, high-grading or project sequencing options, external alignment, optimum time period of investment, biases encountered and how to mitigate them. To mitigate above identified issues, inclusion of mitigation in the FID process, through DE/DRB alignment, project sequencing, market condition scenarios, technology maturity review, debiasing methods, external stakeholder engagement, and optimize time to FID, including transformation and implementation process is presented as part of the study’s conclusion.
Metatheories for Information Literacy
Authors: Choi Jeongbae
Published: October 2022

This poster argues for a metatheoretical approach that investigates philosophical questions produced by the difficulties and disagreements within scientific disciplines in a reflexive manner. This approach provides support for a more consistent foundation of IL in conjunction with an in-depth discussion among researchers and more advanced theories and practices in the field. The poster will explore aspects of IL to which metatheory can contribute such as (1) principal concepts relevant to IL, (2) an understanding of how to achieve ‘literacy’, and (3) the integration of the internal and external elements of IL practices. To this end, it adopts a qualitative content analysis of principal frameworks, standards, and models of IL to compare the explicit and implicit metatheoretical—ontological, epistemological, and axiological—assumptions within existing IL theories and practices. This poster will use a ‘case study’ of the conventional data-information-knowledge-wisdom (DIKW) model with regard to disparate conceptualizations and their practical implications.
From Information Literacy to College Success: Ensuring Equitable Educational Experiences for First-Generation Students, A Practitioner’s Perspective
Authors: Deng Liya
Published: October 2022

This poster contributes to this ongoing discourse by elucidating the prominent role academic libraries can play in first-generation student learning and engagement. The author details the process of planning and developing a brand-new credit-bearing library research course to illustrate how tailored information literacy initiatives addressing the learning needs of first-generation students can be a viable solution to the problem of disempowerment in higher education. The poster highlights a practitioner perspective on major aspects of the course implementation, including needs analysis, content creation, assessment techniques to evaluate both student learning and teaching effectiveness in this semester-long course, along with challenges encountered along the way.
Integrating a New Framework for Inclusive Evaluation
Authors: Becker Kristen
Published: October 2022

Diversity and inclusion are critical elements of community-based organizations; however, many agencies do not have the information necessary to incorporate diversity, equity, inclusion, and social justice (DEIJ) elements into their daily operations. Nevertheless, libraries and other community-based organizations must provide services and programs to all populations at little or no cost. However, they may lack available data or the willingness of employees to engage in evaluation efforts such as strategic planning, which are necessary to ensure inclusive and equitable programs and services. Research (George et al., 2018) shows that many employees do not engage in strategic planning efforts because the process is cumbersome and daunting, they feel the goals do not apply to them, or they do not believe changes will be meaningful and long-lasting. Continual evaluation is critical in identifying demographic changes in the community while introducing culturally-sensitive programs and services.
Shifting Roles
Authors: Kociubuk Jacqueline , Mueller Amy , Wardrip Peter , Willett Rebekah
Published: October 2022

This paper examines the shifting roles of youth service librarians and museum educators during the COVID-19 pandemic. While changes in job duties, processes and day-to-day practices were inevitable, the article argues that practitioners viewed their service as continuous with pre-pandemic roles. Based on interviews with 20 practitioners, the article analyzes two constructs that emerged as professionals described their pandemic roles: guiding principles and collaboration. Not only did these discursive constructs provide a sense of continuity, they also served to advocate for the role of libraries and museums. These findings indicate the importance of reflecting and drawing on guiding principles and collaborations to make decisions about services during times of crisis.
Incorporating Marginalized LIS Educators into LIS Programs Through Remote Work Options
Authors: Shaffer Gary , Cooke Nicole , Hands Africa , Hirsh Sandra , Subramaniam Mega
Published: October 2022

The global pandemic has fundamentally changed the way that people work and learn, and has had a disproportionate impact on Black, Indigenous, and other people of color (BIPOC) (Marcelin, et al., 2021). Throughout the pandemic, all work (including higher education) moved to a fully remote work model. The goal of this panel is to explore the idea of remote work for library and information science (LIS) faculty in the long-term, and particularly discuss the positive implications that this work model could have for those who are BIPOC and/or otherwise marginalized. This is a critical discussion for LIS programs to engage in as the information professions currently face a moment of reckoning and they must work to bring equity for BIPOC colleagues and address the needs of LIS faculty.
Curriculum SIG: LIS Curriculum from Past to Present
Authors: Burress Rene , Li Xiaofeng
Published: October 2022

The curriculum SIG will examine how the history of curriculum in  LIS education impacts the LIS curriculum of today.
Dr. Rene Burress, Dr. Xiaofeng Li, and Holly Hebert will share results from their work answering the research question, “How did the LIS curriculum prepare librarians competencies in diversity, equity, and inclusion to address today’s social justice issues in their libraries and communities?”
Dr. Suliman Hawamdeh will discuss how revisiting our understanding of data, information and knowledge impacts curriculum development and will shape the future of information and knowledge profession and the development of LIS competency-based curriculum.
Dr. Elizabeth Burns will share results of a study that will explore the extent to which LIS programs dedicate attention to diversity, equity, and inclusion in their curriculum.
And with the future in mind, Dr. Yong Ju Jung and Dr. Soo Hyeon Kim present thoughtful educational principles and strategies for how to provide the most effective learning experiences for students in online makerspace courses.
Cultural-based digital archive approach to enrich student users’ curriculum interpretation and worldview
Authors: Yuen Yee Lin Elaine , Leslie Catherine Amoroso
Published: October 2022

In the 21st century, digitalization is essential to optimize preservation and conservation of museum artifacts.  Digital archives provide critical.extension value and relevant information resources that enrich users' cultural knowledge and connection through object analysis.  This study explores the potential of HistoryPin, a free online application for cultural storytelling, to expand student users’ worldview concept and interaction with museum artifacts through a series of curated collections as a learning and engagement tool. 

A collaboration between Kent State University Museum and the School of Fashion’s Historic Textiles course in Spring 2022, this case study identified cultural artifacts including textiles, costumes, and related accessories to illustrate and support course topics. Artifacts representing a range of geographic areas were selected, digitized, and presented with images in different views, cultural and historical information, and linked data in the virtual tour setting of HistoryPin. Students from both online and in-person sections experienced a virtual exhibition of artifacts, which reinforced and extended class content for further interpretation and engagement. 

Advanced interactive technologies, such as comments, favorites, and thought/image sharing on different social media, from HistoryPin allowed students to reflect on various perspectives related to cultural objects. After each section of the course, researchers gathered student users’ interactive comments shared on HistoryPin. A content analysis approach of emergent themes revealed the impact and contributions of museum artifacts. Moreover, a targeted survey provided sub-analyses on the cultural-based digital archive approach which informed an overall assessment of the impact in enriching student users’ virtual museum experience.
College Students’ Fake News Discernment
Authors: Bak Hyerin
Published: October 2022

The purpose of this study was to investigate variables that may be related to college students’ fake news discernment, inspired by Potter’s cognitive media literacy model (2004). The investigated variables included college students’ ability to discern fact from opinion, critical thinking skills, beliefs in their control over situations or experiences (locus of control), and the degree to which they engage in and enjoy thinking (need for cognition). The study employed a sequential explanatory mixed-methods research design.

The survey quantitatively measured 296 college students’ fact and opinion discernment, critical thinking skills, need for cognition, and locus of control. Critical thinking was a variable positively correlated with the fact and opinion discernment, as well as the need for cognition respectively. The follow-up interview data with 19 college students further explained the survey results and their media literacy practices. They described how they discern fact from opinion and evaluate information when reading news online. They stated that polarized media environments and their prior knowledge made information evaluation difficult when reading news online. The participants also described the importance and motivation of discerning fact and opinion and evaluating information in news reports.

The study findings inform considerations for media literacy education which strengthens students’ skills regarding fake news discernment. This study suggests future work that further investigates the studied variables, such as developing the fact and opinion discernment instrument with borderline statements and developing a media literacy model in the context of news reading.
Going Back to Get the Stories
Authors: Evans Sarah , Keeton KYmberly , Molina Lacy , Byun Mimi
Published: October 2022

In the United States, children’s book publishing experienced significant shifts throughout the 20th century, starting with the establishment of dedicated children’s books departments in the 1920’s through to late century changes in printing technology leading to the cost-effective publication of full color non-fiction for youth. Each generation experienced children’s books differently.

            One constant was the sparse availability of books representing any child who was not white. As in Rudine Sims Bishop’s analogy, these youth easily found windows and sliding glass doors in their books but rarely found the self-affirming mirror. Conversely, white children had many mirrors but far fewer opportunities to view unfamiliar experiences nor enter new worlds to discover empathy for others.

            Today’s children are growing up with increasingly diverse representation in the available literature. To fully understand the significance of this moment, we must “go back and get” the experiences of the children who grew up in the 20th century. In this oral history project, we collect individual’s memories of reading and stories from their youngest years through adolescence. Participants are drawn from diverse backgrounds, with an emphasis on people who identify as Black, Latinx, Asian, and/or Indigenous. Findings illuminate the overlooked literacy experiences of people of color and the impact of childhood reading. This project provides insight into the historical impact of library services and the importance of contemporary libraries providing children with diverse literature.
Critical Race Theory as Innovative Pedagogy in LIS
Authors: Dunbar Anthony , Zamir Hassan , Chancellor Renate , Day Grady Siobahn , Dunbar Anthony , Gray LaVerne , Kumasi Kafi
Published: October 2022

The wake of the racial awakening summer of 2020, which led to an interest convergence for racial justice along with the subsequent chilling of racial justice progress serves as the context for this engaging and thought provoking panel. Further contributing to the significance of this panel has been the misinformation, dog whistling, and weaponizing tactics related to critical race theory. While library and information studies has incorporated diversity and cultural based pedagogies into some of the LIS curriculum; critical race theory specific praxes remain anomalies in the discipline. The panel will discuss CRT specific courses currently taught in LIS accredited programs, the racial battle fatigue that highly impacts LIS faculty who teach and research within CRT frameworks, as well as some of the future technological possibilities related to CRT pedagogical frameworks.
Assessing Open Access Scholarly Communication Practices of Early and Mid-Career Researchers in Canada
Authors: Ayeni Philips
Published: October 2022

Open access (OA) to research outputs is fundamental to promoting equity of access to scientific information and knowledge. Although there’s a positive paradigm shift towards OA, actual OA publishing practices tend to lag among researchers. Using a mixed-methods approach, this study investigated OA publishing practices of researchers in Canada.
The Global Automotive Industry Stock Returns During the COVID-19 Pandemic
Authors: Villarreal Samaniego Jesús Dacio , Santillán-Salgado Roberto J. , Escobar Saldivar Luis Jacob
Published: October 2022

This study analyzes the relationship of firm-level ESG scores and stock returns from a worldwide database for the automotive industry. It measures the significance of the ESG and CFP relationship during the last decade, and includes a comparison of those firms with different levels of ESG scores, as well as between firms with ESG scores and to firms that lack such scores. A quasi-experimental difference-in-differences (DID) design and a panel data are estimated to examine the impact of ESG scores and ESG combined scores on firms’ stock return before and during the COVID-19 pandemic period. The results suggest that sustainable actions during the pandemic lessened stock returns, as evidenced by the negative coefficients of the ESGC and ESG scores. The interaction terms with firm size, revealed that ESGC and ESG scores had a positive relationship with stock returns during the pandemic. Thus, larger firms’ returns benefited from higher ESG scores during the COVID-19 crisis. The performance of the stratified sample firms’ stock returns in the context of the COVID-19 sanitary emergency is an original contribution to the literature on the ESG-CFP relationship.
Developing a Transgender Health Information Resource Mobile App: Participatory Design and Agile Development (Preprint)
Authors: Morse Brad , Soares Andrey , Kwan Bethany M. , Allen Marvyn , Lee Rita S. , Desanto Kristen , Holliman Brooke Dorsey , Ytell Kate , Schilling Lisa M.
Published: October 2022

BACKGROUND

Despite the abundance of health information for people who identify as transgender and gender diverse (TGD) on the Internet, much of the content is found on social media channels, leaving individuals to vet the information for relevance and quality.

OBJECTIVE

We developed a prototype transgender health information resource mobile app (TGHIR app) to provide credible health and wellness information for people who are TGD.

METHODS

We partnered with the TGD community and used a participatory design approach including focus groups and co-design sessions to identify user needs and priorities. We employed Agile software development methodology to build the prototype TGHIR app. A medical librarian and physicians with expertise in transgender health curated a set of 96 information resources that made up the foundational content of the prototype. To evaluate the prototype TGHIR app we assessed the app with test users using a single item from the System Usability Scale (SUS) to assess feature usability, qualitative interviews to explore our lowest rated feature, and using the Mobile Application Rating Scale (MARS) to evaluate overall app quality and the quality along six key domains.

RESULTS

Thirteen people who identified as TGD rated their satisfaction with 9 of 10 app features as ‘good’ (n= 7) to ‘excellent’ (n= 2), one feature – the ability to filter to narrow TGHIR resources- was rated as ‘okay’. The overall MARS score was 4.20 out of 5 after 2 weeks of use, indicating a good quality mobile application. The information score received the highest rating at 4.75 out of 5.

CONCLUSIONS

Community partnership and participatory design are effective in the development of the TGHIR app resulting in an app with satisfying features and an overall good quality rating. Test users felt that the TGHIR app would be helpful for people who are TGD and their care partners.