bluuebunny/crossref_metadata_2025 huggingface dataset:
Dampak Lingkaran (Circle) Pertemanan Terhadap Moral dan Karakteristik Mahasiswa
Authors: Astuti Mardiah
Published: March 2024

This research discusses the impact of friendship circles on the morals and characteristics of students. The article aims to examine how social interactions can influence one's attitudes, behaviors, and values. The goal is to help students understand the importance of choosing friends wisely because our social environment can greatly influence how we perceive the world and how we choose to interact with others. The method used in this research is qualitative, and the results indicate a deep understanding of social and human phenomena, such as in this context, how friendship circles affect the morals and characteristics of students. Qualitative research results are typically presented in the form of descriptive narratives based on data collected through interviews, observations, or document analysis. The research findings may indicate that students with friendship circles characterized by strong and positive values tend to exhibit better morals and characteristics. They are more likely to make ethical decisions, show empathy towards others, and behave consistently with moral principles. Additionally, the research may also suggest that friendship circles can serve as a crucial source of social support, assisting students in facing challenges and pressures in their daily lives and studies
Literasi Kesehatan Melalui Edukasi Cuci Tangan Menggunakan (Waterless Hand Soap) Pada Siswa Paud Karya Bunda Mandiri
Authors: Susanti Sani , Bangun Melly Br , Pricilia Yolanda , Suci Delli , Ridoansih Thomas , Ayuning Vista , Padmawati Fitri
Published: March 2024

This research aims to educate hand washing movements using (waterless hand soap) as health literacy for early childhood. This research was carried out at Paud Karya Bunda Mandiri with research subjects namely children aged 5-6 years. The approach to this research was to use a qualitative approach. Data collection techniques are through observation, interviews and documentation. The results of the research show that teachers and preschool children can understand the explanation of health literacy through hand washing education using (waterless hand soap). The hand washing movement using (waterless hand soap) is present as a solution in Health literacy in preschool children who are not provided with a place to wash their hands at school
Analisis Kesulitan Membaca Permulaan Siswa Sekolah Dasar
Authors: Khofiyah Anisa Nidaul , Frestava Vitnes Ingkaning , Azifa Linda Rustiya Nur
Published: March 2024

Early reading difficulties in elementary school students are an important problem in the educational process. The aim of this research is to determine the factors that influence initial reading difficulties, as well as the types of difficulties students face in initial reading based on several related studies. Various factors such as the environment, psychology, and internal maturity of students can be the main causes of reading difficulties. Types of difficulties include a lack of understanding of letters, difficulty pronouncing words, and limitations in reading sentences or paragraphs. This research uses qualitative methods through literature study. The data analysis technique used in this research is content analysis. The results illustrate the various difficulties experienced by students, including difficulties in recognizing letters, difficulties in pronouncing, and difficulties in reading words, syllables, sentences, as well as aspects of incorrect pronunciation. solving initial reading difficulties includes the important role of teachers in providing learning that suits students' needs, parental support in providing motivation, as well as creating a social environment that supports the process of learning to read. By overcoming initial reading difficulties, it is hoped that elementary school students can develop their reading skills effectively to support better academic development
Model Pembelajaran Learning Cycle 5E Terhadap Keterampilan Critical Thinking Matematis Materi Fungsi Ditinjau dari Kemampuan Awal Siswa
Authors: Susanti Tri , Jamilah Jamilah , Ardiawan Yadi
Published: March 2024

This research aims to improve students' critical thinking or critical thinking skills which are divided into three levels, namely students who have high level, medium level, and low-level critical thinking through the application of the Learning Cycle 5E learning model in class X. This research is quasi-experimental research namely the development of true experimental design with Nonequievalent control group design research design through Posttest-Only Control Design carried out at Sukake 1 Public High School. The sample selected used Cluster random sampling, namely class X MIA 1 which was used as the experimental class. Data collection was carried out by trial at SMA Negeri 2 Menyuke followed by research school at SMA Negeri 1 Menyuke using the Learning Cycle 5E learning model and post-test final test to determine students' mathematical critical thinking skills at high, medium, and low levels, interviews to find out student responses regarding the results of the answers. The t-test results for both normal and homogeneous distributions obtained a significance value (2-tailed) = 0.031 < 0.05 with the decision H_1 being accepted. It was proven that there was a significant difference between the learning outcomes in the control class and the learning outcomes of students in the experimental class. Descriptively, students show improvement. Students also experienced quite good improvement. So, it can be concluded that the Learning Cycle 5E learning model provides an increase in critical thinking skills
Implementation of the Policy Merdeka Belajar: A Study at SMA Negeri 1 Pacitan Regency
Authors: Senatama Gandung , Annshori Muhammad Faqih
Published: March 2024

This article finds a discussion to follow-up implementation of the merdeka belajar policy in Indonesia. Through the merdeka belajar or can be interpreted as freedom to learn is a concept that aims to create freedom of thought and innovation. Currently, 100 percent of high scholl, vocational and junior high school levels throughout East Java implement SMIs for the 2023/2024 academic year. Since its estabilishment in Pacitan Regency at the senior high school, there have only been 8 public and private high school out of a total of high schools. The method in this article is a descriptive qualitative analysis. Data collection techniques are carried out by an interview process then see the suitability and match between theory and facts in the field. The results of this article found that the first component of policy implementation from Edward III, namely communication is which occurred at SMA Negeri 1 Pacitan Regency has been going well even though there is often a different understanding of information from the center because of a person’s interpretative power. In the bureaucracy, the branch of the East Java Provincial Education Office through supervisors monitors the implementation. Regarding resources, although it seems sudden because the process of socializing this curriculum is fast, the resources at SMA Negeri 1 Pacitan Regency are fast to make adjusments. Furhermore, the disposition even though inistially ther was no funding for the merdeka belajar curriculum, the school finally decided with the committee to use the BOS fund and Committee Fun for learning purposes
Olah Kata Sosio-Kultural
Authors: Kami Kanisius , Artawan Gede
Published: March 2024

This research aims to describe the phenomenon of word processing which has socio-cultural meaning. This type of research is qualitative research. Qualitative research is research used to obtain more in-depth data, namely data that contains meaning. The meaning in question is the actual data in the form of words, sentences and discourse. The data in this research are words, phrases, sentences written by social media users which imply socio-cultural meaning. Data collection techniques in this research are library techniques and note-taking techniques. Library technique is a data collection technique by examining books and journal articles that are related to the problem being solved. The note technique is a technique for noting several forms that are relevant for research on written language use. The data analysis technique in research is descriptive analysis through the steps of identifying data, classifying data, presenting data, and drawing conclusions. As a result of this research, the researcher found five examples of socio-cultural words, including: 1) Black skin, curly hair, I'm Papuan Bae sonde bae land of Timor lebe bae 3) Jogja is special, the country is special, the people are special, Bali Island Attractive Gods, Ama Mawolo, Ina Marawi.
Kurikulum Sastra Berbasis Teknologi pada Era Digital
Authors: Kami Kanisius , Artika I Wayan
Published: March 2024

This research aims to describe the technology-based literature curriculum in the digital era. This type of research is library research with the object of research is technology-based literary curriculum in the digital era. The data of this research is in the form of verbal description that contains information about technology-based literature curriculum in the digital era, which is related to the underlying principles and alternative concepts of technology-based literature curriculum in the digital era. The data was obtained from sources such as books, research articles, and scientific journal proceedings. The data sources were selected based on considerations the credibility of the owner of the idea or publication. the accuracy of the source, especially regarding novelty, detail, and completeness. Objective balanced and acceptable, and (d) the availability of complete information about the data source for tracking and communication. The data analysis technique is content analysis or content a sis from the data source to the conclusion. The results in this study found several basic elements that can be accommodated in a technology-based literature curriculum in the digital era, including the use of digital media, interactive learning, e-learning platforms, the use of learning aids, digital skills development, and digital creativity
Crystal Al-Doped ZnO Thin-Film Preparation by Sputtering Deposition using a Mixed-Powder Target
Authors:   National Institute of Technology, Sasebo College, Okishin, Sasebo, Nagasaki 857-1193, Japan, Satake Takahiko , Ohshima Tamiko , Aoqui Shin ichi , Kawasaki Hiroharu
Published: March 2024

Al-doped ZnO films were prepared by sputtering deposition using mixtures of Al2O3 and ZnO powder targets. The film quality depended on the conditions of the target powder. The deposition rate, crystallinity, and transparency of films prepared with new, pressed powder targets were higher than those prepared with used, nonpressed powder targets. In addition, we found that pressurizing the new-powder target and increasing the substrate temperature resulted in thin films with high transparency and electrical conductivity
State Observers/Kalman Filters are Generally Unsuitable for Feedback Control While a Far More Rational and Superior Solution is Available
Authors: Tsui Chia-Chi
Published: March 2024

-An observer that estimates system state vector x(t) is a state observer. Although a state observer can generate state feedback control signal Kx(t) where the constant gain K can bese parately designed before its realizing observer, the actual observer feedback system cannot have its loop transfer function equal K(sI – A)-1B, the loop transfer function of the direct state feedback control, for a great majority of plant systems. Because loop transfer function determines the sensitivity function and robust properties of the corresponding feedback system, this implies that the robust properties of the Kx(t)-control are failed to be realized by state observers for a great majority of plant systems.Because robustness against system model uncertainty and terminal disturbance is foremost of feedback control even above performance, state observers are unsuitable for feedback control. Although this problem has initiated a vibrant robust control research in the past 40+ years, the result of that research has been unsatisfactory if parameter K is designed separately and prior to observer design. As a result, control theory remains essentially stagnant and a large amount of works still applied Kalman filters and state observers to feedback control applications. Fortunately, this vital problem has found a fundamentally novel yet decisively satisfactory solution, that is to design parameter K based on the key observer parameters! These new observers are not restricted to be state observers, and can have freely designed and reduced observer order for the first time, and thus can guarantee the full realization of loop transfer function and robust properties of their corresponding Kx(t)-control. Such an observer exits for a great majority of plant systems!In addition, this new design principle is very simple to be learned, and adjusted very easily. Thus, a design methodology that can achieve high performance and robustness for general L-T-I systems is finally developed
AI in Education 2023
Authors: Gander Tim , Shaw Brendon
Published: March 2024

The integration of artificial intelligence (AI) tools in education has emerged as a significant paradigm shift. As we navigate this new landscape, it is essential to understand the adoption and use of these technologies in educational settings. Some valuable insights into AI's global trends and potential in education are available from OECD-Education International (2023), highlighting a need to understand privacy concerns and equitable access. Guidelines and advice have also been made available for New Zealand schools from the Ministry of Education (2024). However, there currently needs to be more comprehensive studies of AI in education that focus on the specific context of Aotearoa, New Zealand.
This report seeks to meet that need. Educators from throughout Aotearoa were invited to participate in a survey conducted between August and November 2023. The survey aimed to assess the landscape of AI implementation in schools, exploring practices, challenges, and potential positive outcomes associated with AI tools in education. This research seeks to inform policymakers, educators, and stakeholders to facilitate informed decision-making to advance educational practices.
Through this research, we hope to contribute to the ongoing dialogue on AI in education and its implications for teaching and learning in Aotearoa.
Community-based tourism in Ecuador: Notes in times of pandemic
Authors: Bravo Lucia Loor , Macias Nila Plaza , Valdes Zoe Medina
Published: March 2024

The COVID-19 pandemic has severely affected tourism activities. The economic and social consequences for countries dependent on this sector are serious. In Ecuador, tourism is important for development. The government proposes to reactivate it by promoting national tourism. This article aims to reflect on the challenges facing tourism activities in Ecuador, especially community tourism during the pandemic. The dialectical relationship between development dimensions is analyzed with the method of dialectical materialism, and it is applied to community tourism, overcoming the positivism that regards this activity as a source of income basically. Analysis and synthesis were applied to the literature review to draw generalizations. The findings highlight the importance of promoting conscious tourism related to sustainable human development and the good life. Identify the relationship between health and safety destinations. Develop community tourism and understand the characteristics of post-COVID-19 tourists. The conclusion is that there is a need to rethink the way tourism is conceived and developed. Community tourism must be analyzed in relation to the structural problems of the country. It must be sustainable and inclusive in all respects in order to be a factor in national development.

 
Primary Central Nervous System Lymphoma, Treatment Outcomes - 10 Year Experience. Single Center Study
Authors: Nizic Ajla , Balic Lejla , Ceric Timur , Omerhodzic Ibrahim , Burazerovic Lejla , Saric Vasvija , Mameledzija Emina , Hasanefendic Berina
Published: March 2024

Background: Primary central nervous system lymphoma(PCNSL) is an aggressive, rare form of Non-Hodgkin lymphoma, characterized by the absence of systemic disease. There are limited data and no strictly defined guidelines for management of PCNSL. Objective: The aim of this study was to report a 10 year experience of PCNSL treatment, to evaluate treatment outcomes and asses Progression Free and Overall Survival of these patients. Methods: Study was conducted on the Haematology Clinic, Clinical center University of Sarajevo, BH, in the period from January 2012.-December 2022. Total sample of 24 patients were enrolled. All have undergone diagnostic surgery. Patients were treated with regimens based on High dose Methotrexate, with/without whole brain radiotherapy as consolidation. Treatment response was captured by imaging techniques. Patients who have relapsed were evaluated with imaging techniques and treated according to Methotrexate-based treatment protocols. Results: We have captured equal gender distribution. The median age of patients was 59.5 years (range 20-79). Pathohistological analysis confirmed DLBCL diagnosis in 22 patients, T cell lymphoma and anaplastic large cell lymphoma, each in 1 patient. Chemotherapy, chemotherapy combined with WBRT and radiotherapy were given to 5, 18 and 1 patients, respectively. The overall complete response rate (CR) was 87,15%.  Those receiving combined modality-treatment had higher CR than those receiving chemotherapy (94,4% versus 60%). Out of 24 patients, 11 of them relapsed. The median time to relapse was 29 months (from 1 to 105). After second line of the treatment, CR was 54,5%, while 45,45% of patients died during the treatment. 4 patients relapsed for the second time with median time to relapse of 9 months (from 2 to 77). 2 year OS rate was 67%, and the median OS rate was 45,9 months. 2 year PFS rate was 31%. Conclusion: The OS and PFS rates indicate the usage of new drugs and consolidation with autologous stem cell transplantation in patients with PCNSL in order to achieve better treatment outcomes.
Clinical Manifestations of European Borreliosis on the Skin in Acute, Subacute and Chronic Disease
Authors: Dautovic Sajma , Salihbegovic Adis , Dervisevic Emina , Gojak Refet , Cengic Meliha , Duratbegovic Damir , Mostarac Nermin , Begic Jasmina , Ahmed Haroon
Published: March 2024

Background: Lyme borreliosis is a multisystemic infection caused by the spirochete Borrelia burgdorferi. Erythema migras is the main clinical marker of the disease. Objective: This study aimed was to investigate the frequency and clinical manifestations of European borreliosis on the skin, and to determine the significance of these findings for diagnosis and therapy. Methods: A retrospective-prospective clinical study of outpatients treated and monitored in a private clinic of an infectologist was conducted over nine years from to 2013-2021. The study was clinical, descriptive and analytical in nature. Results: In the investigated period, 509 (30.8%) patients with borreliosis symptoms were treated. EM in our patients occurred under the following conditions: a) ringed redness, b) redness of target cels and d) continuous round or oval redness of different sizes of individual redness, or multiple occurrences with primary dissemination. Skin changes with multiorgan chronic symptoms of borreliosis occurred in 67.7% of cases the including: walking redness of different shapes and sizes, pink borreliosis stretch marks, white borreliosis stretch marks, borreliosis palms and soles, psoriatic changes, Acrodermatitis chronica atrophicans, Scleroderma circumscripta-morphae, Erythema nodosum, Granuloma anulare and Lichen striatus et atrophicans. Of the 509 patients treated for borreliosis, 32.3% with multi-organ symptomatology had no skin changes. Conclusion: The skin manifestations of European borreliosis are multi-layered and Erythema migrans are basic, but not the only markers of the disease. ‘Pink borreliose stretch marks, “white borreliosis striae”, “borreliosis palms or soles”, and intermittent redness accompanied by itching are unique markers for the diagnosis of chronic borreliosis, if they are manifested.
OHCA in Bosnia and Herzegovina: Before and During the COVID-19 Pandemic
Authors: Sljivo Armin , Abdulkhaliq Arian , Mulac Ahmed , Lukic Vlado , Margeta Ivona , Rako Marija , Kapisazovic Emira
Published: March 2024

Background: Out-of-hospital cardiac arrest (OHCA) refers to the cessation of mechanical cardiac activity outside healthcare facilities which requires prompt intervention and intensive resuscitative efforts. The COVID-19 pandemic has caused significant disruptions to OHCA systems-of-care, adversely affecting every component of the chain of survival. Objective: The objective of this study was to examine the potential impacts of the COVID-19 pandemic on OHCA events, to draw comparisons between the period before and during the COVID-19 pandemic. Methods: This cross-sectional study encompassed data pertaining to all OHCA incidents attended to by the Emergency Medical Service of Canton Sarajevo, covering the period from January 2017 to December 2022, before and during the COVID-19 pandemic. Results: During observed period, a total of 1418 [796 (56.1%) before and 622 (43.9%) during COVID-19 pandemic] OHCA events have occurred in Canton Sarajevo of which 297 (20.9 %) [180 (12.7%) before and 117 (8.2%) during COVID-19 pandemic] obtained ROSC. After a 30-day period following the ROSC) it was observed that the predominant outcome, accounting for 181 (12.7%) [106 (7.4%) before and 75 (5.2%) during COVID-19 pandemic] of cases, was a complete recovery. An examination before and during COVID-19 pandemic revealed a decline in OHCA during the year 2021 and 2022 when COVID-19 pandemic was at its highest in the country Being younger, quicker EMT response time and individuals with the initial rhythm of VF or VT were significantly associated with obtaining ROSC (p<0.05). Only 48 (3.3%) of 1418 OHCA events were assisted by bystanders There was no report of AED usage. Conclusion: In conclusion, our investigation highlights the impact of the COVID-19 pandemic on OHCA events in Canton Sarajevo, revealing a decrease in OHCA incidence and a reduction in cases achieving ROSC. Notably, EMT response time was shorter during the pandemic.
Insights Into the Employability of Midwifery Graduates. A Case Study of the International Hellenic University
Authors: Theodoridou Anatoli , Koukou Zoi , Taousani Eleftheria , Katsantoni Eleni , Antonakou Angeliki
Published: March 2024

Background: This study examines the employability and career trajectories of International Hellenic University’s (IHU) midwifery students who graduated between 2016 to 2021, with a focus on undergraduate curriculum changes. Objective: To comprehensively examine the post-graduation journey of recent IHU Midwifery graduates. This includes shedding light on their employment trajectories, satisfaction levels, and the practical application of academic knowledge. Through this exploration, the study seeks to inform educational strategies to ensure alignment with the evolving needs of midwifery professionals in Greece. Methods: Online questionnaires that explored post-graduation experiences, perspectives on the study program, and future plans. The questionnaires consisted of a mix of open and closed-ended questions and were completed by 273 recipients. The study was conducted from May to September 2023, with participant anonymity maintained. Statistical analysis was performed using SPSS. Results: This study revealed differences between graduates of the ‘old’ and ‘new’ midwifery undergraduate curriculum. There were notable variations in the perceived impact of the six-month internship on employment. The study also highlighted the impact of the COVID-19 pandemic on educational experiences, emphasizing the nuanced challenges faced during clinical practice, practical training, and simulation training. Finally, the self-employed professionals and those employed in the public sector expressed higher satisfaction with the alignment of their employment with their undergraduate studies, than their counterparts in the private sector (p=0.038). Conclusions: Our study offers valuable insights into job placement, knowledge sufficiency, and the impact of the pandemic on midwifery undergraduate education. These findings can guide tailored strategies for improved education and holistic professional development, ultimately enhancing maternal and neonatal care.
Association of Anti-Ro/SSA and Anti-La/SSB Autoantibodies With Pregnancy Outcome in the General Population
Authors: Dragoutsos Georgios , Tsiggalou Christina , Oikonomou Efthymios , Bothou Anastasia , Trypsiannis Grigorios , Nikolettos Konstantinos , Damaskos Christos , Garbis Nikolaos , Kyriakou Dimitrios , Nalbanti Theopi , Iatrakis Georgios , Nikolettos Nikolaos , Tsikouras Panagiotis
Published: March 2024

Autoimmune diseases encompass a diverse array of disorders that disturb the optimal functioning of the immune system, which is to eliminate the ‘foreign or/and dangerous’ to mistakenly target the body’s own tissues. The exact causes and etiologies of these diseases are multifactorial and mostly still unclear. Ro/SSA autoantibodies and La/SSB, could be found in Sjögren’s disease (SJ), systemic lupus (SLE) and other autoimmune disorders. Smoking, stress, UV exposure, vitamin D deficiency, and other genetic and environmental factors have been identified as risk factors for rheumatic diseases. Over the years, an ever-increasing incidence of these diseases has been observed in the general population, with the female sex being at increased risk for their occurrence. This fact raises the question of what should be the management of these pathological entities during pregnancy. Taking into account the very significant impact on the quality of paitients’daily life and the seemingly augmented prevalence of autoimmune diseases. as well as their preference in the female population, the reasonable question arises as to what should be the optimal management of these diseases in the context of pregnancy. Given the limited data of the global medical community regarding the etiological factors and mechanisms that trigger the onset of rheumatic diseases, the management of pregnant women is a complex conundrum that health professionals are challenged to face and solve.
Unveiling the Nexus: Depressive Symptoms and Medication Adherence in Hypertensive Patients’ Self-care: A Systematic Review
Authors: Stamoulis Theofilos , Dragioti Elena , Gouva Mary , Mantzoukas Stefanos , ourakos Michael
Published: March 2024

Background: Hypertension, a significant public health concern, is frequently linked to emotional disorders like depression. Research shows a reciprocal link between depression and hypertension, potentially influencing patients’ adherence to self-care routines. Objective: This systematic review aimed to examine the association between depressive symptoms and aspects of self-care, with a focus on medication adherence in individuals diagnosed with hypertension. Methods: Following PRISMA guidelines, a systematic review was conducted by searching PubMed, PsycINFO and Scopus until March 17, 2023. The included studies involved quantitative primary research conducted in English, focusing on adults (≥18 years) diagnosed with hypertension and experiencing depressive symptoms. Observational studies were assessed using the Newcastle-Ottawa Scale, and randomized controlled trials were evaluated using the revised Cochrane Risk of Bias Tool (RoB 2.0). Due to the great diversity of these studies, a narrative synthesis of the results was undertaken. Results: A total of 18 studies involving 6,131 people with hypertension, that met our eligibility criteria were ultimately included. The reported rates of depressive symptoms ranged from 4% to 43%. Of these studies, nine reported a statistically significant association, showcasing an adverse impact of depressive symptoms on medication adherence. The remaining nine did not confirm the above. Conclusion: This systematic review highlights the diverse body of research exploring depressive symptoms and medication adherence among individuals with hypertension. The review suggests a need for increased attention to self-care practices, particularly in relation to adherence to antihypertensive medication. However, it recommends the conduction of more robust longitudinal studies to comprehensively explore this relationship.
The Impact of Outdoor in Nature Mindfulness on the Mental Well-being of Children and Adolescents. A Mental Health and Cross-cultural Approach
Authors: Argyriadis Alexandros , Kopanakis Emmanuel , Koutras Panagiotis , Louvaris Konstantinos , Mammi Antonia , Psychogiou Maria , Katsarou Dimitra , Vieira Isabel , Drakopoulou Olga , Argyriadii Agathi
Published: March 2024

Background: Mindfulness, originating from ancient meditation practices, has garnered substantial scientific interest in recent decades due to its potential to enhance various aspects of well-being. The rise of scientific interest in mindfulness has led to the development of Mindfulness-Based Stress Reduction (MBSR) and other mindfulness-based interventions (MBIs), which have demonstrated positive effects on stress reduction, emotional regulation, and cognitive flexibility. Objective: This study aimed to explore the characteristics and applications of mindfulness, investigate its impact on mental health, and assess the potential benefits of combining mindfulness with nature-based interventions in promoting the well-being of children and adolescents. Methods: This review draws from existing literature, scholarly articles, and empirical studies related to mindfulness, nature exposure, and their effects on mental health. Results: The results highlight the manifold benefits of mindfulness in different populations, including health professionals, patients, children, adolescents, and the general public. Mindfulness practice has been associated with notable reductions in stress, anxiety, and depression, and has shown positive effects on brain plasticity and cognitive functioning. Furthermore, the integration of mindfulness with exposure to natural environments holds potential for enhanced stress reduction and cognitive restoration. Conclusion: The findings underscore the potential of mindfulness as a cost-effective and accessible intervention to promote mental health across diverse age groups and settings. Further research should explore the specific mechanisms and long-term effects of this integrated approach to optimize its benefits.
Medical, Surgical and Experimental Approaches to Acute Mesenteric Ischemia and Reperfusion
Authors: Matkovic Zoran , Aleksic Zoran
Published: March 2024

Background: Acute mesenteric ishemia(AMI) is a rare but very serious disease with high rate of mortality and morbidity. About 1-2% of all gastrointestinal disease is AMI. Mortality is about 60-80% and depends of time between starting of symptoms and establishing of diagnosis, type AMI, comorbidities. AMI is often in older population with coronary syndrom and atrial fibrilation. AMI may be occlusive(embolisatio arteriae mesentericae superior(AMS), or thrombosis of AMS, mesenterial vein thrombosis) and nonoclusive form(NOMI). NOMI is rising in critical ill patients in shock or sepsis. Pathophysiology of AMI is very complex and significant role in this proces has ischemia and also reperfusion. Reperfusion injury including oxidative stres, inflamation, infection. The best diagnostic approach is CT angiography but after high clinical suspicion on AMI. Patients have sudden, catastrophic abdominal pain, vomitus, bloody diarrhoea. Therapy is multidisciplinary-basic treatment(resuscitation with cristaloids, antibiotic, anticoagulans...), surgical treatment-resection necrotic segments of intestinum without anastomosis or endovascular treatment. In early phases conservative treatment is possible( vasodilatation, thrombolysis). In some countries there are Intestinal Stroke Centers (ISC) in which patients with AMI have better prognosis. Because of progressive nature of AMI( rapide worsening) rare are clinical study,but there are many experimental study on animal models. Most of experimental study investigate protective effects of some supstances on damage on intestinum and remote organs during ishemia and reperfusion. Objective: To present literature data of clinical and experimental study, describe experiments on animal models and mention supstances whit promising results in protective strategies during AMI. Methods: We analysed Pubmed by using mesh terms such as acute mesenteric ischemia, intestinal injury, reperfusion, experimental study, clinical and therapeutic approach. Results: Sudden abdominal pain resists on opioids analgetics, high rate of CRP, hyperlactatemia, increase of D dimer is enough for suspicion of AMI. Often is delayed in establishing of diagnosis of AMI. CT angiography has sensitivity of 94%. Pneumatosis is sign of necrosis of intestinal wall. Classical surgical approach is dominant, more than 70%,. Endovascular treatment became often last few years. Experimental studies investigate occlusion of AMS with atraumatic clamp, with schemia and reperfusion in different intervals Most animals models are on wistar male rats. Conclusion: AMI has still high rate of mortality. Better diagnostic and therapeutic principles (shorter interval between appearance of symptoms and starting of therapy, multidisciplinary approach, higher percent of endovascular procedures), could decrease mortality. Experimental studies on animal models may be succesfull in development of new clinical, conservative approaches in the early phases of AMI in the future.
Are aneroid and digital sphygmomanometers as reliable and accurate as mercury sphygmomanometers?
Authors: Mathew Jassal , Bahuleyan Biju
Published: March 2024

Background: The accurate measurement of blood pressure (BP) is crucial for effectively treating hypertension, which stands as a primary risk factor for both cardiovascular disease and premature mortality. The shift from mercury to nonmercury sphygmomanometers in developing countries due to environmental concerns prompts an evaluation of the accuracy of these alternatives.

Aims and Objectives: The objectives of this study were to evaluate the precision of non-mercury instruments in diagnosing hypertension and to analyze interarm differences in both systolic and diastolic BP using three different sphygmomanometers.

Materials and Methods: Sixty subjects aged 18–25 were included. BP measurements were taken from both arms using different types of sphygmomanometers. Statistical analysis involved paired t-tests, Chi-square tests for correlations, and a significance threshold of P < 0.05.

Results: Significant differences in systolic BP readings were observed between the gold standard (mercury manometer) and digital/aneroid devices (P = 0.00). Compared to the mercury manometer, both digital and aneroid devices showed limited accuracy in detecting hypertension. Kappa agreement was moderate at 0.57. Despite high specificity (100%), sensitivity was lower at 44.4%, indicating a risk of missing true positive cases. Both devices exhibited a sensitivity of 25%, with fair to poor agreement (kappa values) in identifying cardiovascular risk compared to the mercury reference.

Conclusion: This study underscores the diminished reliability of both aneroid and digital devices in detecting hypertension and assessing cardiovascular risk using specified interarm BP criteria. These findings emphasize the crucial need for further research and caution when relying on non-mercury devices in clinical settings.
Clinical features and management of women with Mayer-Rokitansky-Küster-Hauser syndrome in a Thai population
Authors: Matemanosak Phawat , Peeyananjarassri Krantarat , Klangsin Satit , Wattanakumtornkul Saranya , Dhanaworavibul Kriengsak , Choksuchat Chainarong , Getpook Chatpavit
Published: March 2024

Objective This study aimed to describe the clinical features, associated extragenital anomalies, and management of Mayer- Rokitansky-Küster-Hauser (MRKH) syndrome in a Thai population.Methods This retrospective study analyzed the medical records of 96 patients with MRKH syndrome diagnosed and treated at a university hospital and tertiary referral center in southern Thailand between 2000 and 2022.Results The study included 96 patients with MRKH syndrome. The most common symptom was primary amenorrhea (88.5%), followed by difficulty or inability to engage in sexual intercourse (9.4%) and pelvic mass (2.1%). Notably, 80.3% of the patients did not have extragenital malformations and were diagnosed with MRKH type I (typical form), whereas 19.7% were categorized as MRKH type II (atypical form). Skeletal malformations were the most frequent extragenital anomalies and were present in 19.5% of patients, with scoliosis being the most common skeletal condition. Other extragenital malformations included renal (8.5%) and neurological (1.0%) abnormalities. Clinical vaginal examination revealed complete atresia in 21.8% and vaginal hypoplasia (median vaginal length, 3 cm) in 78.2% of the patients. Half of the patients did not receive treatment because they had not engaged in sexual intercourse. In this cohort, 41.7% of the patients had no difficulty performing sexual intercourse. Hence, self-dilation therapy or concomitant dilation was recommended. Only eight patients (8.3%) underwent surgical reconstruction of the vagina.Conclusion This study confirmed the complexity and heterogeneity of the phenotypic manifestations of MRKH, including the degree of vaginal atresia and types and rates of associated malformations.
Ruska propaganda u Srbiji i na Zapadnom Balkanu: kanali na mreži Telegram
Authors: Greisman Polina
Published: March 2024

Tokom poslednjih nekoliko godina Rusija se više puta mešala u unutrašnje stvari drugih zemalja – na primer, tokom izbora u Sjedinjenim Državama 2016. i u Ujedinjenom Kraljevstvu 2019. godine. Postoje bezbrojni primeri njenog uplitanja u tuđe poslove, kao i propagande koja se odvija putem interneta. Ruski propagandni arsenal obuhvata alatke kao što su državni mediji koji emituju program namenjen publici u drugim zemljama (Russia Today, Sputnjik i drugi), zvanični državni nalozi na društvenim mrežama, kao i čitave armije lažnih naloga koji su u više navrata uočeni u kampanjama dezinformisanja i mešanja u politiku drugih država. One su se mnogo puta našle među razlozima za uvođenje sankcija pojedincima bliskim ruskoj vladi, ali i predsedniku Vladimiru Putinu lično. Upečatljiv primer nekoga ko je organizovao ovakvu vrstu mešanja i zbog toga se našao na meti sankcija je Jevgenij Prigožin, koga su nazivali „Putinovim ličnim kuvarom“ i koji je bio povezan sa Agencijom za istraživanje interneta poznatom kao „Fabrika trolova“ ili „Prigožinovi trolovi“. Iako je sam Prigožin poginuo u avionskoj nesreći, njegova „fabrika trolova“ i dalje radi. Srbija nije izuzetak kada je reč o državama čiji su se unutrašnji poslovi našli na udaru mešanja ruske vlade. To se, međutim, zbog prijateljskih odnosa Rusije i Srbije, retko iznosi u javnost. Takođe, takve radnje nisu očigledne, i nije ih lako na prvi pogled okarakterisati kao propagandu i uplitanje. Zbog toga ćemo u ovoj studiji razmotriti ovo pitanje i na primeru Srbije pokazati kojim se metodama propagande i intervenisanja Rusija koristi u zemljama koja se mogu nazvati „prijateljskim“. Posmatrano sa istorijskog stanovišta i u poređenju sa drugim zemljama na Balkanu, odnos Rusije i Srbije je verovatno jedan od najdubljih i najzanimljivijih. Ova vrsta odnosa ne može se nazvati isključivo političkim ili ekonomskim, jer prijateljstvo ovih država počiva na temeljima istorije, religije i etno-jezičke zajednice. Međutim, uprkos tim naizgled čvrstim odnosima, Rusija tokom poslednjih dvadeset godina Srbiju koristi kao platformu za svoju propagandu, držeći se pritom prilično uhodanih metoda . Uz to, Rusija u Srbiji i regionu koristi i svoju meku moć.
Teaching WebAR development with integrated machine learning: a methodology for immersive and intelligent educational experiences
Authors: Semerikov Serhiy O. , Foki Mykhailo V. , Shepiliev Dmytro S. , Mintii Mykhailo M. , Mintii Iryna S. , Kuzminska Olena H.
Published: March 2024

Augmented reality (AR) and machine learning (ML) are rapidly growing technologies with immense potential for transforming education. Web-based augmented reality (WebAR) provides a promising approach to delivering immersive learning experiences on mobile devices. Integrating machine learning models into WebAR applications can enable advanced interactive effects by responding to user actions, thus enhancing the educational content. However, there is a lack of effective methodologies to teach students WebAR development with integrated machine learning. This paper proposes a methodology with three main steps: (1) Integrating standard TensorFlow.js models like handpose into WebAR scenes for gestures and interactions; (2) Developing custom image classification models with Teachable Machine and exporting to TensorFlow.js; (3) Modifying WebAR applications to load and use exported custom models, displaying model outputs as augmented reality content. The proposed methodology is designed to incrementally introduce machine learning integration, build an understanding of model training and usage, and spark ideas for using machine learning to augment educational content. The methodology provides a starting point for further research into pedagogical frameworks, assessments, and empirical studies on teaching WebAR development with embedded intelligence.
The Centre for Chemistry and Technology and the Future of the OPCW
Authors: Anthony Ian
Published: March 2024

With the destruction of the final remaining stockpiles of declared chemical weapons in 2023, the Organisation for the Prohibition of Chemical Weapons (OPCW) must adjust to a new role. The inauguration of the OPCW’s Centre for Chemistry and Technology (CCT) in 2023 provides a new resource to assist the organization and the international community in reducing and eliminating the threat from chemical weapons. Now that the CCT is operational, it is important to build momentum behind a substantive programme of work. Projects for the programme could be grouped into four thematic categories: understanding technological developments; chemical forensics; broadening geographical representation; and tailored training programmes. The CCT should be led by a director, who should work with a newly established Office of Science and Technology to develop the centre’s strategic direction. To provide the CCT with stable and secure financing, a trust fund for the CCT should be established.
DEVELOPMENT OF IMPROVEMENT MEASURES MARKETING AC-TIVITIES OF THE ENTERPRISE
Authors: Tkachenko Irina , Anisimova Olga
Published: March 2024

The article discusses the issues of improving the marketing activities of an enterprise as a necessary condition for ensuring the stable functioning of the or-ganization in the conditions of economic sanctions. Based on an analysis of the in-ternal and external environment, the strengths and weaknesses of AQUA-GROUP LLC, Salsk, Rostov region, engaged in the trade of auto chemical products for car washes, were identified, and opportunities and threats from the market were identi-fied. The main characteristics of the market for autochemical products in the Rus-sian Federation are highlighted. The structure of the industry has been studied, an analysis of competitors, suppliers and consumers of the auto chemicals market has been carried out. A strategy has been developed and measures for its implementa-tion have been planned, aimed at improving marketing activities, including search-ing for new suppliers in the context of import substitution, expanding the market of potential customers by entering new formats of trading platforms. An analysis of the most popular marketplaces was carried out, the principles of their operation, tariffs for delivery and storage of products were studied. A cargo transportation scheme for AQUA-GROUP LLC has been developed at the 1st and 2nd stages of developing sales on marketplaces. The additional profit received by entering the trading platforms of the Ozon and Yandex Market marketplaces was calculated.
ADAPTATION OF HUMAN RESOURCES MANAGEMENT MODELS TO STIMULATE THE DEVELOPMENT OF MINING ENTERPRISES
Authors: Gusov Auzbi , Sylvain Gbade
Published: March 2024

This article examines the issue of adapting HR management models in the context of mining companies in order to stimulate their development. In today's dynamic economic environment, mining companies face a number of challenges that require effective personnel management to ensure competitiveness and sustainable growth.

The author analyzes the features of personnel management in the mining industries, highlighting key aspects such as the specifics of the production process, the characteristics of the workforce and the risks associated with occupational safety. Then modern models of personnel management are considered, including approaches to the selection, development and motivation of employees.

The concept of adapting these models to the specifics of mining companies, taking into account their unique needs and challenges, is also proposed, which includes the development of specialized training and development programs, the introduction of motivation systems that take into account the dangers and difficulties of the working environment, as well as the creation of flexible management structures for rapid adaptation to changing market conditions.

In conclusion, the importance of continuous improvement of human resources management models in mining companies in a rapidly changing economic environment is emphasized, which will allow them not only to survive, but also to thrive in modern competitive conditions.
INVENTORY OF LAND PLOTS BASED ON THE GEODETIC JUSTIFICATION OF COMPLEX CADASTRAL WORKS OF THE VILLAGE OF BAYKALOVO, SVERDLOVSK REGION
Authors: Tatarchuk Anna , Gusev Aleksey , Anisimov Yuriy , Inysheva Valeria , Belichev Aleksey
Published: March 2024

In this paper, the analysis of the results of cadastral works on the sections of the map of the village of Baykalovo is carried out. Cadastral work includes topographic and geodetic measurements, land assessment and cadastral planning. Geoinformation systems and specialized programs were used for the analysis. It is shown that residential buildings and a warehouse area prevail on the map sections. Digitized sections of the map were used for data analysis. The analysis of the correspondence of these cadastral documents to the actual situation on the ground was carried out. It is shown that the analysis of the results of cadastral works is an important tool for identifying errors and inaccuracies in cadastral data. In addition, the data and the difference in the areas of different zones on the map sections are presented. These data allow us to assess the differences between the actual characteristics of the objects and the data recorded in the cadastral documents.
ANALYSIS OF THE IMPACT OF CHANGES IN THE GLOBAL ECONOMY ON THE COMPETITIVENESS OF RUSSIAN SMALL AND MEDIUM-SIZED ENTERPRISES
Authors: Van YUe , Gusov Auzbi
Published: March 2024

In the context of globalization and accelerated development of the world economy, Russian small and medium-sized businesses face the need to adapt to constantly changing conditions. The article provides an overview of the main factors affecting the competitiveness of Russian small and medium-sized enterprises, as well as explores possible ways to improve their positions in the global economy.

The analysis of the impact of these changes on the competitiveness of Russian small and medium-sized enterprises is an urgent task. Understanding the factors that determine the success or failure of enterprises in the market allows you to develop development strategies and make effective management decisions.