bluuebunny/crossref_metadata_2025 huggingface dataset:
HBME1 and CK19 in Non-Invasive Follicular Thyroid Neoplasm with Papillary-like Nuclear Features (NIFTP) vs Other Follicular Patterned Thyroid Lesions.
Authors: Sadiq Qandeel , Sekhri Radhika , Dibaba Daniel , Zhao Qi , Agarwal Shweta
Published: March 2021

Background: Thyroid neoplasms with follicular architecture can have overlapping morphologic features and pose diagnostic confusion amongst pathologists. Various immunohistochemical stains have been investigated as potential diagnostic markers for PTC; amongst which HBME1 and CK19 have gained popularity. Non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) poses similar diagnostic challenges with interobserver variability and is often misdiagnosed as adenomatoid nodule or follicular adenoma. This study aims to evaluate expression of HBME1 and CK19 in NIFTPs in comparison to other well differentiated thyroid neoplasms and benign mimickers. Method: 73 thyroid cases diagnosed over a period of 3 years at Methodist University Hospital, Memphis, TN were included in this study: 9 NIFTP, 18 papillary thyroid carcinoma (PTC), 11 follicular variant of papillary thyroid carcinoma, invasive (I-FVPTC), 24 follicular adenomas (FA), and 11 multinodular goiters/ adenomatoid nodules (MNG). A tissue microarray (TMA) was constructed and HBME1 and CK19 IHC was performed.Results: HBME1 was expressed in 77.8% NIFTPs, 88.9% PTC, 81.8% I-FVPTC, 16.7 % FA, and 18.2% MNGs. CK19 expression was seen in 66.7% NIFTPs, 83.3% PTC, 81.8% I-FVPTC, 33.3% FA and 45.4% MNGs. Difference in expression of HBME1 and CK19 was statistically significant for NIFTP vs FA (qualitative; p<0.05) and NIFTP vs MNG (p<0.05). No statistically significant difference was found for HBME1 in NIFTP vs PTC (conventional and FVPTC), p>/= 0.2. Sensitivity of HBME1 and CK19 for NIFTP were 78% and 67%, ~88% each for PTC, and 89% and 100% for FVPTC respectively, while specificity of HBME1 and CK19 for NIFTP were 53% each, ~62% each for PTC and ~55% each for FVPTC. Conclusion: Our study indicated that HBME1 and CK19 are valuable markers in differentiating NIFTPs from morphologic mimics like follicular adenoma and adenomatoid nodules/ multinodular goiter. While HBME1 and CK19 are both sensitive in diagnosing lesions with PTC like nuclear features, CK19 stains a higher number of benign lesions in comparison to HBME1. No increase in sensitivity or specificity in diagnosis of NIFTP, PTC or FVPTC was noted on combining the two antibodies.
Screening and Identification of Ovulation-Inducing Regulatory Factors in Bactrian Camel
Authors: Wang Qi , Zhang Quan wei , Gan Ze , Li Hai jiang , Li Yi na , Zhao Xing xu , Zhang Yong
Published: March 2021

Background: Camelidae are inducing ovulators, ovulation is tightly regulated by multiple factors, and understanding the biological mechanisms underlying follicular development, hormone secretion and ovulation requires investigation of the potential molecular pathways. However, little is known about the pathways of these factors in the camel. To screening and identification candidate biomarkers after inducing ovulators in ovary.Methods: In this paper, the quantitative proteomics method iTRAQ analysis technology was used to analyze the proteomic differences of ovarian before and after induced ovulation in Bactrian camels. The differentially expressed protein was validated by Western blot, qRT-PCR and Immunofluorescence staining analysis.Results: A total of 5,075 ovarian expressed proteins were detected, and 404 proteins were differentially expressed (264 up-regulated, 140 down-regulated) in samples from treated versus control camels. Gene ontology annotation identified potential functions of the differentially expressed proteins (DEPs). We validated the differential expression for a subset of these proteins using western blotting and immunofluorescence staining. Three DEPs (FST, NR5A1 and PRL) were involved in neurochemical signal transduction, endocrine and reproductive hormones regulatory processes. KEGG analysis indicated the involvement of several pathways, such as calcium, cAMP, gonadotropin-releasing hormone, MAPK, and neuroactive ligand-receptor signaling pathways, further suggesting that the induced ovulation process depends on the hypothalamic-pituitary-ovarian axis. Conclusions: This study is the first to perform quantitative proteomic investigation by iTRAQ labeling and LC-MS/MS to identify differentially expressed proteins induced ovulation in Bactrian camels. Our study has revealed distinct molecular functions and metabolic pathways that are active during reproduction in Bactrian camels. These results have demonstrated the pivotal role played by 3 DEPs in the modulation and activation of the reproductive axis during induced ovulation in the Bactrian camel, followed by the measurement of selected proteins using more targeted methods, offers a promising approach for studying potential mechanism of ovary development and ovulation.
Lung in chronic autoimmune diseases and hypersensitivity – how to separate these from idiopathic pulmonary fibrosis
Authors: Popper Helmut H. , Stacher-Priehse Elvira , Brcic Luka , Rammp Florian , Nerlich Andreas
Published: March 2021

Background

Lung involvement in autoimmune disease (AID) is not uncommon, and may precede other organ manifestations. The histologic pattern is variable and difficult to interpret. Another problem was recently encountered: chronicity presenting with fibrosing pneumonia. This resulted that patients with chronic AID and usual interstitial pneumonia (UIP) were excluded from antifibrotic therapy. Creating a new category of UIP with autoimmune features (IPAF) for patients with AID enabled treatment for these patients. This however raised the opinion, that a pathological investigation for the underlying disease is not necessary.
Results

We retrospectively evaluated 66 cases of AID, 31 cases of hypersensitivity pneumonias (HP), and 10 clinically confirmed usual interstitial pneumonia/idiopathic pulmonary fibrosis (UIP/IPF) cases. 12 additional cases could not be assigned into any of these categories. Acute AID presented with lymphocytic interstitial pneumonia, immune complex deposition, cytotoxicity for specific cell compartments, and alveolar hemorrhage. Subacute patterns most often presented with organizing pneumonia, whereas chronic pattern most often presented as UIP. Granulomas were present in some patients. UIP pattern was the most common presentation in chronic AID and HP, whereas NSIP was rather rare.
Conclusion

The most important, statistically significant feature differentiating chronic AID or HP, from UIP/IPF are lymphocytic infiltrations into myofibroblastic foci. Other features such as granulomas, Langhans giant cells, and protein deposits were significantly associated with AID and HP, but were not encountered in all cases. This study demonstrated that the morphological analysis can uncover the possible etiology in many cases, and a more specific diagnosis can be provided to the clinicians.
A Comparison between Total Intravenous Anaesthesia Using Propofol plus Remifentanil and Propofol plus Sevoflurane in Children undergoing Fibreoptic Bronchoscopy：A Randomized, Single-Blind Study
Authors: Chen Fang , Wang Zhuli , Huang Bingwu , Lu Jiachao , Chen Mengmeng , Zeng Ruifeng
Published: March 2021

BackgroundFibreoptic bronchoscopy is an important used to evaluate and manage paediatric patients with respiratory disease.This study aimed to compare the effect of two different anaesthesia methods, propofol combined with remifentanil and propofol combined with sevoflurane, on children undergoing fibreoptic bronchoscopy (FOB).Method:Sixty children were enrolled and randomly divided into two groups. In the remifentanil group (Group R), the patients were induced with 4 mg•kg− 1 propofol + 4 µg•kg− 1 remifentanil (slow intravenous injection) and maintained with 0.3–0.5 µg•kg− 1•min− 1 remifentanil. In the sevoflurane group (Group S), the patients were induced with 2 mg•kg− 1 propofol and 8% sevoflurane and maintained with 4–6 vol% sevoflurane. Heart rate (HR), mean blood pressure (MBP) and pulse oxygen saturation (SpO2) were monitored and recorded at four time points: baseline (T0), when the bronchoscope reached glottis (T1), the time of lavage (T2), and the time of brush biopsy (T3). Waking time and the satisfaction score of physicians were recorded, and emergence agitation (EA) was evaluated in the postanesthesia care unit (PACU). Finally, any supplementary medicine or adverse events were also recorded.ResultsCompared with group S, the waking time was significantly shorter and the incidence of EA was significantly lower in Group R. During bronchoscopy, significant differences in MAP or HR were not observed between the two groups at T0. Compared with group S, the HR of group R was significantly decreased at T1, T2 and T3, and MAP was significantly decreased at T1, but the fluctuation range was within 20% of the baseline. A significant difference in SpO2 was not observed between the two groups at any time point. No significant differences in the operation time of FOB, the incidence of complications, such as moving, hypoxemia, bronchospasm, and bucking, or the level of satisfaction were observed between the two groups.ConclusionsTotal intravenous anaesthesia using propofol plus remifentanil in children undergoing fibreoptic bronchoscopy potentially reduces the waking time and decreases the incidence of EA to improve the work efficiency and turnover rate of the outpatient operating room.Trial registrationRegistered at the China Clinical Trial Registry (http://www.chictr.org.cn) (ChiCTR1900026098).
A Qualitative Exploration of Barriers in Accessing Community Pharmacy Services for Persons with Disability in Addis Ababa, Ethiopia: A phenomenological Study
Authors: Meshesha Solomon Getnet , Dagnachew Nebiyou , Mekonen Zelalem Tilahun
Published: March 2021

Background: It was estimated that over a billion people have a disability and around 110 to 190 million experienced significant difficulties in functioning. Similarly, there were over 5 million and 32,630 individuals with disability in Ethiopia and Addis Ababa, the capital city of Ethiopia, respectively. Health care is a human right, yet access barriers to healthcare remain one of the major challenges among people with disabilities. Community pharmacists are often the health system point of entry for most patients. Therefore, the aim of this study was to explore the barriers to community pharmacy service for individuals with physical, visual and hearing disability in Addis Ababa, Ethiopia.Methods: A phenomenological qualitative study design was employed to explore the barriers to community pharmacy service for individuals with Physical, Visual and Hearing disability. All members from Ethiopian National Association of the Blind (ENAB), Ethiopian National Association of the Deaf (ENAD) and Ethiopian National Association of persons with Physical Disability (ENAPPD) and all community pharmacy professionals in Addis Ababa were the study populations in this study. The analysis was made using content analysis where ideas were classified into themes manually.Result: All informants with disability pointed out that community pharmacy services were not accessible to them. The study explored transportation, physical, communication and medication price were the main barriers to obtain community pharmacy services among individuals with visual, physical and hearing disabilities. Respondents also witnessed that pharmacists provided proper counseling and were also cooperative and willing to help them.Conclusion: This study indicated that individuals with disability experienced different access barriers to community pharmacy services. Further studies are recommended to identify other community pharmacy disparities and access barrier to pharmacy services and propose possible solutions.
WAYS FOR IMPROVING OF FISCAL-ACCOUNTING REGULATION TO THE CONTEXT OF AGRICULTURAL EXPORTS IN UKRAINE ACCORDING TO THE WORLD TRENDS
Authors: Voitseshyn Vasyl , Shevchuk Oleg
Published: March 2021

The object of research: the procedural order of fiscal and accounting regulation of revenues from export agricultural products (export receipts, the export duty).
Investigated problem: obtaining stable and repetitive connection between the accounting part, the fiscal part of the regulation and exports of agricultural goods with possibility of improvement.
The main scientific results: it is revealed that the first stage of fiscal-accounting regulation of exported agricultural products is transactions’ accounting on accounts. It should be noted that, after the abolition of the mandatory sale in Ukraine, there is no need to apply the distributive account in export of agricultural products. It will help to reduce the time of enrollment the currency and its using by exporters for their needs. It is determined too, that the second stage of the regulation is the export receipts and revenues from the export duty. Moreover, using economic (mathematical) modeling, based on correlation-regression analysis, it is illustrated positive effects for reducing of export duty rates on revenues from export agricultural products in Ukraine.
The area of practical use of the research results: Government of Ukraine in formation of export strategy, and exporters – in the context of accounting.
Innovative technological product: the regulation technology of the cyclical accounting and fiscal parts in agricultural exports with using modeling econometric analysis for determination of direction of its development.
Scope of the innovative technological product: Ukraine’s Government practice in using mathematic modeling for determination of trends of agricultural exports.
Effective Organization of Extracurricular Activities in Azerbaijan Schools and Near and Far-Abroad Countries
Authors: Ismayilova B.
Published: March 2021

Introduction. The main task of secondary schools is to prepare a new generation for activity, develop the creative potential of an individual, educate a creatively thinking younger generation, possessing the entire set of intellectual and cultural qualities. In this regard, the correct organization of extracurricular activities is of great importance. The aim of this article is to analyze the experience of conducting extracurricular activities in Azerbaijan schools and near and farabroad countries. Research methodology and methods. In 2019 a pedagogical experiment was conducted among 219 pupils of urban, regional and rural schools in Azerbaijan. Initially, a preliminary survey was conducted among pupils of IV, VI, VIII, X, XI grades and a few months later a second survey was conducted among 453 pupils with the question "In what direction do you prefer to work in extracurricular activities?". A survey was used as a research method. Results and discussion. The international experience of carrying out extracurricular activities is described. Proposals were put forward for the effective organization of extracurricular activities in accordance with the requirements of the XXI century. Azerbaijan experience in organizing extracurricular activities is described. In the process of the pedagogical experiment, in extracurricular activities, the pupils tried to improve their skills in various areas, using educational computer games, role-playing games and developing simple educational games. During the experiment, we found that pupils from different grades voluntarily joined the extracurricular activities. A second survey was conducted among pupils and the results show that they were more interested in educational games and computer setting operations. Conclusion. Research results show that the correct organization of extracurricular activities has a significant impact on the intellectual development of pupils, contributes to the achievement of good learning outcomes in the educational process at school. In connection with the relevance of this topic, theoretical and practical research related to various forms of extracurricular activities and solving problems of their organization and implementation will be continued.
Applying Website Rankings to Digital Health Centers in the United States to Assess Public Engagement: Website Usability Study
Authors: Calvano Joshua David , Fundingsland Jr Edwin Lauritz , Lai Deborah , Silacci Sara , Raja Ali S , He Shuhan
Published: March 2021

Background

As the public increasingly uses the internet to search for resources and information regarding health and medicine, it is important that health care organizations provide adequate web resources. Website usability refers to the ease of user experience on a website. In this study, we conducted usability analyses on digital health center websites.

Objective

The primary aims of this study were to (1) replicate a preexisting usability scoring methodology for digital health centers; (2) apply and test this replicated usability scoring methodology on a sample set of digital health center websites; and (3) derive recommendations from the results on potential areas of improvements for our sample of digital health center websites.

Methods

Website usability testing was conducted from March 1, 2020, to March 15, 2020. We replicated a methodology and scoring system from previous literature and applied them to digital health center websites. Our sample included 67 digital health centers that were affiliated with US universities or hospital systems. Usability was split into the following four broad categories: accessibility, marketing, content quality, and technology. Usability tools were used to score websites in each of the four categories. The composite of the key factors of each category was used to generate a general usability and overall usability score for each website.

Results

The category with the highest average score (6.3) was content quality. The content quality score also had the highest SD (2.18) and an SE of 0.27. The lowest performing category was technology, which had an average score of 0.9. The technology score also had the smallest SD (0.07) and an SE of 0.01.

Conclusions

Our data suggest that content quality, on average, was the highest scoring variable among digital health center websites. As content is crucial to digital health knowledge, it is justified that digital health centers invest more resources into creating quality content. The overall lowest scoring variable was technology. Potential reasons for this finding include designated funding for servers, a lack of regulatory frameworks for social media presence and liability, and infrequent website audits. An easy approach for improving this variable is increasing website speed. Accessibility is another area that organizations can potentially improve. We recommend that these organizations perform periodic audits of their web presence with usability tools.
The Use of DNA Barcoding and Phylogenetic Analysis to Improve Identification of Usnea spp. Based on ITS rDNA
Authors: Jannah Miftahul , Hariri Muhammad Rifqi , Kasiamdari Rina Sri , Handayani Niken Satuti Nur
Published: March 2021

Lichen of the genus Usnea is quite common being used as a traditional herbal remedy. This genus is characterized by thallus, which is very similar among the species, leads to some difficulties in distinguishing them. In Indonesia, such research report on the availability of this genus based on their morphological characteristic is minimal. This might be due to too high morphological similarities among them. The molecular character, which is based on the DNA Barcode of Internal Transcribed Spacer (ITS) rDNA sequences, with its conserved region (5.8S) and varied region (ITS1 and ITS2), are becoming essential characters on identifying as well as analyzing the phylogenetic. The current study then proposed to identify and draw the species dendrogram of species within the Usnea genus obtained from Mount Lawu Forest of Central Java and Turgo Forest of Yogyakarta based on their phylogenetic and phenetic analysis. The dendrogram was constructed with UPGMA using the simple matching coefficient, whereas the phylogenetic tree was constructed with Maximum Likelihood (ML) using Kimura-2 parameter with 1000 bootstrap. The data were unable to draw phenetic relationships among the subgenus Usnea and Eumitria members. The phylogenetic tree shows the primary two clades, distinguishing the subgenus Usnea and Eumitria. The ITS rDNA sequence was able to identify most of the Usnea species.
Adsorption of Indigo Carmen Dye by Using Corn Leaves as Natural Adsorbent Material
Authors: Fadhil Omar H. Fadhil H. , Eisa Mohammed Y. , Salih Dina Abdalrahman , Nafeaa Ziad R.
Published: March 2021

In this paper, the ability of using corn leaves as low-cost natural biowaste adsorbent material for the removal of Indigo Carmen (IC) dye was studied. Batch mode system was used to study several parameters such as, contact time (4 days), concentration of dye (10-50) ppm, adsorbent dosage (0.05-0.25) gram, pH (2-12) and temperature (30-60) oC. The corn leaf was characterized by Fourier-transform infrared spectroscopy device before and after the adsorption process of the IC dye and scanning electron microscope device was used to find the morphology of the adsorbent material. The experimental data was imputing with several isotherms where it fits with Freundlich (R2 = 0.9937) and followed pseudo second order kinetic. The highest removal percent was equal to 91% of the dye which makes the corn leaves a suitable efficient material for the removal of IC dye from aqueous solutions.
Encarnación, cognición y representación: ¿cómo piensan el cuerpo las ciencias cognitivas?
Authors: Zapata Cano Rodrigo
Published: March 2021

Traducción del francés al español de Rodrigo Zapata Cano

Las ciencias cognitivas intentan analizar el funcionamiento de la mente y el conocimiento. Constituyéndose en los años cuarenta y cincuenta del siglo XX, han utilizado el computador y la informática como modelos de referencia y han permitido desarrollar muchos proyectos tecnológicos (inteligencia artificial) y responder a múltiples desafíos epistemológicos. Pero desviadas, sin duda, por tan hechizantes perspectivas de su proyecto de conocer la cognición (memoria, lenguaje, consciencia, percepción, atención, dominio de la actividad motriz, etc.), y al caer en el olvido de la especificidad del ser humano, han sido conducidas a producir modelos de los que se excluían sobre todo la experiencia humana y el cuerpo. Francisco Varela (1997) ofrece en el libro De cuerpo presente una síntesis de las actuales tendencias de la epistemología de las ciencias cognitivas con el fin de despejar las lagunas problemáticas, especialmente las que tienen que ver con la relación del cuerpo y la mente. En lugar de pensarlos separadamente, e inspirándose en Merleau-Ponty y el budismo, postula un “entrelazado” del cuerpo y el mundo, en el fondo del cual se realiza la cognición.
Violencia hacia las otras formas de ser mujer y de ser hombre
Authors: Varela Quintero Jonathan David , Mahecha Montañez Andrea Marcela
Published: March 2021

El presente escrito es el resultado del ejercicio investigativo que indagó por las nuevas feminidades y masculinidades presentes en los grados décimos del Colegio Distrital Paulo Freire de la localidad de Usme, Bogotá. Para ello, se analizaron las violencias de las que son víctimas los y las estudiantes que construyen su identidad de género por fuera de los esquemas tradicionales establecidos desde la heteronormatividad. A partir de una metodología cualitativa, se hizo uso de la encuesta y la entrevista para identificar estereotipos de género junto con las formas de violencia que circulan en el espacio escolar. Tales datos fueron analizados con ayuda de la herramienta informática Atlas.ti.
Impact of foliar application of different nano-fertilizers on soil microbial properties and yield of wheat
Authors:   Department of Soil Science and Agricultural Chemistry, Rajasthan College of Agriculture, MPUAT, Udaipur-313 001, India, Meena R.H. , Jat G. ,   Department of Soil Science and Agricultural Chemistry, Rajasthan College of Agriculture, MPUAT, Udaipur-313 001, India, Jain D. ,   Department of Molecular Biology and Biotechnology, Rajasthan College of Agriculture, MPUAT, Udaipur-313 001, India
Published: March 2021

Aim: The present investigation was carried out to study the effect of foliar application nano-fertilizers P, K and Zn on yield, nutrient content and uptake by wheat and soil microbial properties in sub-humid southern plains of Rajasthan. Methodology: The experiment was laid out in triplicate following randomized block design with fifteen treatments comprising foliar application of different doses of Nano P, K and Zn. Results: Foliar application of 1st spray of Nano Zn at 14 days after sowing (DAS) + 2nd spray of Nano Zn at 28 DAS along with 100% recommended dose of fertilizers (RDF) significantly (P=0.05) increased yield attributes and nutrient uptake in wheat. The significantly (P=0.05) maximum microbial population (bacteria and fungi) and microbial biomass-C was obtained with 1st spray of Nano P at 14 DAS + 2nd spray of Nano P at 28 DAS along with 100% recommended dose of fertilizers (RDF). Interpretation: Foliar application of nano fertilizers led to significant improvement of crop productivity of wheat in sub-humid southern plain of Rajasthan. Moreover, the foliar application of nano-fertilizers, i.e., Nano P also stimulated microbial growth by providing nutrients and directly increased their population in soil. Key words: Biomass-C, Foliar application, Nano-fertilizers, Soil microbial population, Wheat productivity
QUANTIFYING WINDOW EFFECTIVENESS TO AFFECT WIND VELOCITY BY EXPERIMENTAL STUDY
Authors: Ridzqo Intan Findanavy , Rochimah Estuti , Soedarno Jerrino
Published: March 2021

Particular ventilation design can create effective natural air movement into the indoor environment by flowing the outside wind. The window, as a kind of ventilation, has various designs. It combines three primary constructions: simple opening, vertical-pivot, and horizontal-pivot opening. Each has a particular characteristic to control air velocity and direction which flows through it. However, the wind is not always certain in the mean of its velocity and direction, which heavily relies on the season. This study is written to investigate the single window’s performance by measuring its effectiveness to control wind velocity in some directions. The effectiveness is conceived as a percentage rate that a window could maintain the outside wind velocity when it flows through the window. This experimental study employs three factors that are wind direction, window design and opening angle. This study operated 1:1 model of ten window designs, a simulation wall, and an electric fan to generate the Building Physics Laboratory's intended wind in the Department of Architecture, Institut Teknologi Indonesia. The result shows that maximum opening angle with perpendicular wind is the most effective situation to flow wind through all window—except simple casement window—with the rate ranging at 85,16% – 123,76%. The wind could also be more speeded up 109,63% – 193,90% when it aligned to all windows. Simple casement window even reaches 266,22% when the wind perpendicular.
Notas sobre a abstração informal na historiografia da arte no Brasil.
Authors: Fernandes Mayã , Pugliese Vera
Published: March 2021

Este artigo tem como objetivo analisar elementos da inscrição do abstracionismo informal na tensão entre o moderno e o contemporâneo na historiografia da arte no Brasil. Embora parte dessa fortuna crítica identifique na abstração uma persistência por parte de alguns artistas em utilizar do paradigma moderno para responder a questões contemporâneas, outros artistas parecem aludir ao abstracionismo informal, experimentando-se e incorporando processos abstratos em outras linguagens e poéticas. Deste modo, propomos contribuir para a necessária revisão do processo de historicização do abstracionismo no Brasil a partir da reflexão sobre alguns aspectos da exposição “Oito décadas da abstração informal”, realizada em 2018 no MASP, a fim de problematizar noções sobre o abstrato na contemporaneidade. AbstractThis article aims to analyze the elements of the informal abstraction inscription in the tension between the modern and the contemporary in Brazilian art historiography. Although part of the critical fortune identifies the persistence of using a modern paradigm in abstraction in order to answer to contemporary questions, other artists such as Leda Catunda, Luiz Aquila and Tatiana Blass allude to informal abstractionism, experimenting with it and incorporating abstract processes in other languages and poetics. Therefore, we propose a contribution to the revision of the historicization process of abstractionism in Brazil investigating aspects of the exhibition “Eight decades of informal abstraction”, held in 2018 at MASP, in order to call into question the main notions about the abstract in a contemporary approach.
CENTRO COMPLEXO E SEMOVENTE: A LINGUAGEM E A VERTIGEM CLARICE LISPECTOR
Authors: Saraiva Americo
Published: March 2021

Este texto tem por objetivo refletir sobre aquele que julgamos ser o efeito mais saliente da escrita de Clarice Lispector. Exímia “artesã” na deformação das formações ideais que nos asfixiam, enrijecendo-nos a vertiginosa potência de existir, a escrita de Clarice tem o dom de nos devolver, estranhados, à nossa centralidade complexa e semovente. Ela estranha a si e a seu mundo para estranhar o leitor e reativar-lhe o “eu” semiótico. Reativado, este “eu” semiótico não apenas toma consciência da sua condição de centro complexo e semovente, sensível a outras formas de vida e à variedade dos afetos que as assediam, mas também torna-se, em consequência disso, capaz de evitar toda redução “naturalizadora” decorrente do exclusivismo de qualquer formação ideal em seu campo de presença.
A INOVAÇÃO DO CONTO INFANTO-JUVENIL EM "A MULHER QUE MATOU OS PEIXES", DE CLARICE LISPECTOR
Authors: Martins dos Santos Karen Larissa , Dias de Araujo Susylene
Published: March 2021

O presente artigo constitui um estudo sobre A mulher que matou os peixes, 1999, de Clarice Lispector e seu objetivo é analisar aspectos da inovação na escrita da autora, considerada pela crítica uma das escritoras mais aclamadas da literatura modernista brasileira. Conhecida na tradição da literatura brasileira por ter escritos livros destinados a adultos, Clarice Lispector inaugurou no Brasil um estilo de escrita própria e diferente da sua época por romper com padrões da narrativa linear e tradicional.
Symmetries and solutions to dissipative hyperbolic geometric flow
Authors: Gao Fang , Wang Zenggui
Published: March 2021

Based on the Lie-symmetric method, we study the solutions of dissipative
hyperbolic geometric flows on Riemann surfaces; In the process of
simplification, the mixed equations are produced. And the hyperbolic
equations are obtained under limited conditions. Considering the Cauchy
problem of the hyperbolic equation, the existence and uniqueness
conditions of the global solutions are obtained. Finally, the phenomenon
of blow up is discussed.
Synthesis and spectroscopic characterization of new solid solution containing Mg(II) and Cu(II) complexes with hexadentate 1,3-propanediaminen, N,N’,N’-tetraacetate (1,3-pdta) ligand: In vitro antifungal activity of 1,3-pdta-Cu(II) complexes
Authors: Stanojevic Ivana , Gitaric Jelena , Asanin Darko , Glisic Biljana , Draskovic Nenad , Zivkovic Sanja , Vasic Tanja
Published: March 2021

New solid solution containing Mg(II) and Cu(II) complexes with hexadentate
1,3-propanediamine-N,N,N?,N?-tetraacetate ligand (1,3-pdta), [Mg(H2O)6]
[Mg0.5Cu0.5(1,3-pdta)].2H2O was synthesized and structurally characterized
by elemental microanalyses, molar conductivity, and spectroscopic (IR and
UV-Vis) measurements. The spectroscopic data of
[Mg(H2O)6][Mg0.5Cu0.5(1,3-pdta)].2H2O were compared with those for
[Mg(H2O)6][Cu(1,3-pdta)].2H2O complex of the known molecular structure
determined by single-crystal X-ray diffraction analysis. In vitro growth
inhibition activity of [Mg(H2O)6][Mg0.5Cu0.5(1,3-pdta)].2H2O and
[Mg(H2O)6][Cu(1,3-pdta)].2H2O against Colletotrichum acutatum and their
effects on this fungus sporulation level are investigated. The obtained
results showed that the highest percentage of inhibition for mycelium growth
was achieved at a concentration of 500 ?g/mL for the investigated complexes.
The biological activities of the investigated complexes were compared with
those for the commercial formulation of fungicide captan (Method 480 SC).
Attractor behaviour of holographic inflation model for inverse cosine hyperbolic potential
Authors: Dimitrijevic Dragoljub , Djordjevic Goran , Milosevic Milan , Stojanovic Marko
Published: March 2021

We study a model of tachyon inflation and its attractor solution in the
framework of holographic cosmology. The model is based on a holographic
braneworld scenario with a D3-brane located at the holographic boundary of
an asymptotic ADS5 bulk. The tachyon field that drives inflation is
represented by a Dirac-Born-Infeld (DBI) action on the brane. We examine the
attractor trajectory in the phase space of the tachyon field for the case of
inverse cosine hyperbolic tachyon potential.
Post-pyrogenic dynamics of the vegetation cover of the Barskoe raised bog (Vologda Region, Russia)
Authors: Malashchuk Anzhelika A. , Philippov Dmitriy A.
Published: March 2021

The study deals with the issues of restoration of peat bogs exposed to the pyrogenic factor. The work was carried out in the Barskoe raised bog, at sites unaffected and directly affected by the ground fire of 2002. A decade later, these sites differed in species composition, phytocoenosis structure, and biomass accumulation rates. Post-pyrogenic changes in the vegetation cover of the raised bog were associated with a slight decrease in species richness, loss of moisture-demanding bog species and an increase of mesophyte’s and xerophyte’s roles, simplification of the mire sites structure towards the loss of complexity, reduction of phytocoenotic diversity, as well as an increase in the dry biomass stocks with a 1.3–1.4-fold decrease in the photosynthetic phytomass and a 6.4–6.7-fold increase in the mortmass. The restoration rate of the mire exposed to pyrogenic transformation can be accelerated by increasing its water table and the prevention of new fires.
Pengaruh Terapi Musik Instrumental Terhadap Tekanan Darah Pada Lansia Hipertensi
Authors: Kholifah Nur , Sutanta Sutanta
Published: March 2021

Background : Hypertensian can occur anyone, both men and women at any age. The elderly are at high risk of developing age-related degenerative diseases such as hypertension, one way to lower blood pressure in hypertensive sufferers using music therapy instrumental . The Aim :To Find out the effect of music therapy instrumental on blood pressure in elderly of hypertension at Panti Wredha Budhi Dharma Umbulharjo Yogyakarta. Methods :This research uses the pra ekperiment with One Group Pretest-Postest. The study population amounted to 52 elderly people , there are 30 samples elderly people by sampling methods using purposive sampling method. The research the method of data analysis uses Wilcoxon. Results : After performing music therapy instrumental showed blood pressure there are 28 people down (normal) and 2 fixed (high). The results ofthe Wilcoxon test, Z count value of -6.174 with p value 0,000 α = 0,05. Conclusion :There is a effect of music therapy instrumental on blood pressure in elderly of hypertension at Panti Wredha Budhi Dharma Umbulharjo Yogyakarta.
PENGARUH INTENSITAS RADIASI MATAHARI TERHADAP PERTUMBUHAN DAN KUALITAS SELADA MERAH (Lactuca sativa L.)
Authors: Timotiwu Paul Benyamin , Manik Tumiar Katarina B. , Ginting Yohannes Cahya
Published: March 2021

Selada merah semakin diminati oleh masyarakat karena memiliki tekstur yang renyah dan warna yang menarik.  Penelitian ini bertujuan untuk mengetahui efektifitas naungan plastik UV dalam mengurangi intensitas radiasi matahari, mengetahui pertumbuhan dan kualitas selada merah di bawah naungan plastik penyaring UV sebagai suatu alternatif pengembangan selada merah di dataran rendah. Penelitian dilaksanakan di Teluk Betung, Bandar Lampung dengan  perlakuan tanpa naungan dan perlakuan menggunakan naungan plastik penyaring UV 14% berbentuk terowongan, masing-masing perlakuan memiliki 30 sampel. Data yang diperoleh di uji menggunakan analisis Uji-t taraf α 5%. Hasil penelitian menunjukkan bahwa rata-rata plastik UV yang digunakan efektif menurunkan intensitas radiasi dari 641 watts.mˉ² menjadi 464 watts.mˉ² (38%), suhu pada siang hari di luar dan di dalam naunganyaitu  37˚C dan 36˚C, dan kelembaban udara di luar dan di dalam naungan hanya 49% dan 50%.  Perlakuan tanpa naungan menghasilkan jumlah daun yang lebih banyak daripada yang di dalam naungan, dan bobot segar tanaman lebih baik pada perlakuan tanpa naungan sebesar 35%.  Tampilan warna selada merah secara visual lebih baik pada perlakuan tanpa sungkup plastik penyaring UV 14% yang menghasilkan tanaman selada dengan warna merah yang dominan.
Jordanian University Students’ Views on Emergency Online Learning During COVID-19
Authors: Al-Salman Saleh , Haider Ahmad S
Published: March 2021

The present study investigates the influence of digital technology, instructional and assessment quality, economic status and psychological state, and course type on Jordanian university students’ attitudes towards online learning during the COVID-19 emergency transition to online learning. A survey of 4,037 undergraduate students representing four Jordanian public and private universities revealed that personal challenges (such as economic and psychological stress) decreased students’ willingness to learn online in the future, while the quality of the online experience (including instructional and assessment quality) improved their attitudes towards learning online in the future. Students also believed that Arts & Humanities courses were better suited for online teaching/learning than Sciences courses, a difference that persisted after controlling for personal challenges and the quality of the online learning experience.
Instructor Social Presence and Connectedness in a Quick Shift from Face-to-Face to Online Instruction
Authors: Conklin Sheri , Garrett Dikkers Amy
Published: March 2021

During the first weeks of the COVID-19 pandemic, instructors at a southeastern university had one week to convert their current face-to-face courses to an online format, under a time frame that did not allow for a “well-designed” online course. The current study investigates how some instructors were able to maintain social presence in the transition to the online environment, and the instructional practices they used to support those continued connections. In a cross-sectional survey of undergraduate and graduate students (N = 432 ) conducted during the last week of the Spring 2020 semester, we asked students to focus on a class that was successful in keeping them in touch with their instructor, content, and peers. Analyses of the data revealed four major themes: connectedness, instructor responsiveness and coaching, online learning best practices such as chunking materials, and empathic facilitation.
Food and Feeding Habit of Two Mugilidae from Lagoon of Grand-Lahou (Côte d’Ivoire) : Liza dumerili (Steindachner, 1870) and Liza falcipinnis (Valenciennes, 1836)
Authors: Kouakou Irène Kessia Fokouo , Kone Tiehoua , Kouato Fulgence , N'da Konan
Published: March 2021

Study of the diet and feeding habits of 104 specimens of Liza dumerili (Steindachner, 1870) and 113 specimens of Liza falcipinnis (Valenciennes, 1836) coming from the artisanal fishing of the Grand-Lahou lagoon was carried out over the period from September 2008 to August 2009. Analysis of stomach contents revealed that these two species of fish feed mainly on diatoms and detritus. It appears that these species are phytoplanktonophagous and detritivores. The diet of Liza falcipinnis does not vary according to the size of the individuals. These two species specialize in the consumption of diatoms, particularly pennate diatoms.
¿Qué leen los adolescentes españoles? Un estudio de los consumos de lectura analógica
Authors: Trigo Ibáñez Ester , Santos Díaz Inmaculada Clotilde , Sánchez Rodríguez Susana
Published: March 2021

This work is part of the project “Determining factors in the reading habits of secondary school students. A study from the variables of the educational context” (PR2017040), funded by the Own Research Plan of the University of Cádiz. The main objective is to know the reading consumption of Spanish teenagers. Specifically, the consumption of analog reading of students of 1st year of Compulsory Secondary Education in Spain is studied. A sample of students from the province of Cádiz (n=664) and from other Spanish provinces (n=192) responded to a questionnaire about their reading habits. It allowed, in the first instance, to determine if informants enjoy reading and, later, to gather information about what and in what format they read, the criteria on which they are based to choose their readings, how much time they dedicate to read and where they get their readings. The results indicate that this sector of the population prefers reading adventure books, chooses books by subject, reads more during holidays and uses their own books. However, it is confirmed that the development of the reading habit is still a subject to pass.
Nuevas alfabetizaciones en un entorno multimodal: nuevas necesidades lectoras para un entorno textual múltiple
Authors: Sánchez Claros Juan Patricio
Published: March 2021

The new technologies of information, the development of the media and the massive presence of multimedia devices have brought a renewal of the traditional concept of literacy. Multimodality in the media, in the dissemination of knowledge and the communication formats have brought a change in the system of reception of media objects and each of its integral elements. This multimodal environment is part of the daily life of students who access through a scenario of screens and images across a virtual environment in which both textual and visual are integrated as an informational continuum that requires to users new interpretation skills. And, consequently, a new approach to media literacy should be the subject of attention from educators.Media literacy implies the need to address new visual skills, new reading skills and especially new skills for integration and analysis, among those who cannot be set aside on the critical apparatus necessary. This paper discusses the content of these skills, some critical tools for multimodal approach speech as well as the role the four substrata of discourse, design, production and distribution, typical of Critical Analysis of Multimodal Discourse are analysed.
Evaluación de la competencia lectora de futuros docentes
Authors: Felipe Morales Andrea , Barrios Espinosa Elvira
Published: March 2021

This paper presents a test aimed at assessing university students’ reading competence –The Reading Competence Test for University Students (in Spanish, Test de Competencia Lectora para Universitarios, Test CLUni)– and the results obtained in the test by prospective Early Years and Primary Education teachers. The theoretical framework underlying the test is followed by description of the pilot stage and the validation process; this included content and expert validity. Next, the test is characterised. It consists of six authentic texts (four continuous and two non-continuous texts) that were selected according to the proposed text types in PISA-2012. Finally, the results obtained in the test by a sample of 288 students in the Bachelor Degree of Early Years (n=148, 51.4%) and Primary Education (n=140, 48,6%) at the University of Málaga in the academic year 2013/4 are presented. Results pertaining the students’ perceptions on the difficulty of the test are also included.
Testes sorológicos no diagnóstico da Covid-19
Authors: Assis Larissa Cristina de , Souza Taisa Izabela Magalhães e , Aninger Gabriel Tavares , Moura Alexandre Sampaio
Published: March 2021

Introdução: Na pandemia causada pelo COVID 19 se torna cada vez mais importante o diagnóstico correto dos casos. Apesar do RT-PCR ainda ser o padrão ouro para diagnóstico de COVID-19, testes sorológicos que detectam anticorpos vêm ganhando cada vez mais importância por serem mais disponíveis, ter resultados liberados mais rápidos e não depender nem de estrutura ou equipe especializada para coleta ou análise.
Objetivo: Analisar as propriedades, limitações, indicações de uso e interpretação de resultados dos diferentes testes sorológicos disponíveis para COVID-19.
Métodos: Revisão da literatura disponível na plataforma PubMed através dos termos “SARS-CoV-2”, “COVID-19”, “testes sorológicos”, e dados fornecidos pelas diretrizes do Ministério da saúde, aliando conceitos epidemiológicos à esses dados.
Resultados: Temos diversos métodos utilizados para identificar anticorpos de maneira quantitativa ou qualitativa. Mais de 60 testes diagnósticos para a COVID-19 estão registrados no Brasil, sendo que a maior parte são testes sorológicos e, dentre estes, a maioria são testes imunocromatográficos. Testes que detectam anticorpos contra o núcleocapsídeo tendem a ser mais sensíveis, enquanto anticorpos anti proteína spike tendem a ser mais específicos. Já existem testes no mercado que detectam ambos, sendo capazes de possuir tanto sensibilidade com especificidade elevadas.
Conclusão: Os testes sorológicos para SARS-CoV-2 estão em alta demanda e são vários os tipos de testes em circulação. É necessário conhecimento das propriedades intrínsecas dos testes e valor preditivo associado, levando em consideração o tempo de curso clínico da doença ao pedir o teste e interpretar seus resultados.
Palavras chave: SARS- CoV - 2; COVID -19; testes sorológicos; acurácia
Wybrane problemy przemysłu mleczarskiego województwa słupskiego w latach 1990–1996
Authors: Rydz Eugeniusz , Barańska Paulina
Published: March 2021

W polskiej gospodarce przetwórstwo spożywcze zajmuje szczególną pozycję, gdyż jest to nadal najważniejsza gałąź naszego przemysłu. Jego udział w produkcji sprzedanej całego przemysłu wynosił w 1996 r. 20,7%. Wyroby przemysłu spożywczego stanowiły około 32% sprzedaży towarów na rynek wewnętrzny i 10% eksportu. Przemysł spożywczy stanowi zatem ważne ogniwo gospodarki narodowej, w tym szczególnie gospodarki żywnościowej kraju…
Skala i struktura inwestycji zagranicznych w polskim przemyśle
Authors: Piasecka Katarzyna
Published: March 2021

Brak dostatecznego kapitału krajowego w okresie transformacji sprawił, iż inwestycje zagraniczne stały się niezbędnym źródłem zasilania procesów rozwojowych kraju. Wraz z wejściem w życie ustawy z dnia 14 czerwca 1991 roku o spółkach z udziałem zagranicznym rozpoczął się stały dopływ do Polski kapitału zagranicznego w postaci inwestycji bezpośrednich …