bluuebunny/crossref_metadata_2025 huggingface dataset:
GRAIN PRODUCTIVITY OF EARLY-MATURING CORN HYBRIDS IN AKMOLA REGION
Authors:   North  Kazakhstan  University named after Manash Kozybaev, Petropavlovsk сity, Kazakhstan, Malitskaya N.V. , Ashirbekov M.Zh. ,   North  Kazakhstan  University named after Manash Kozybaev, Petropavlovsk сity, Kazakhstan, Kuznecova M.A. ,   North  Kazakhstan  University named after Manash Kozybaev, Petropavlovsk сity, Kazakhstan, Auzhanova M.A. ,   Kokshetau University named after Shokhan Ualikhanov, Kokshetau сity, Kazakhstan, Kosanov S.U. ,   Korkyt Ata Kyzylorda University, Kyzylorda city, Republic of Kazakhstan
Published: October 2024

Кукуруза (Zea mays, Poaceae) – является одной их распространенных зерновых культур в мировом земледелии. На продовольственные цели используется около 20% ее зерна. Средняя урожайность в засушливой части богарного земледелия составила 24,4 ц/га. Для производства раннеспелых гибридов кукурузы в Северном Казахстане культуре необходима минимальная сумма активных температур 2200°С. Подобрать скороспелые адаптируемые гибриды кукурузы для возделывания на зерно в сопочно-равнинной зоне Акмолинской области является целью нашего исследования. Учеты и наблюдения по исследованию проводили по методике Государственного сортоиспытания. Из исследуемых гибридов наиболее скороспелыми по длине вегетационного периода являются Киз Уракс и Сары-Арка (стандарт), зерно в початках достигает восковой спелости за 113 суток. Немного длиннее был период у гибридов Целинный 160 – 121 сутки и Будан – 129 суток, также соответствующих раннеспелой группе по классификации ФАО (условный индекс скороспелости), принятый Международной продовольственной и сельскохозяйственной организацией: 100 - 149 суток. Структура урожая раннеспелых гибридов была многокомпонентной. Наибольшая озерненность початка была у гибридов Киз Уракс – 237 зерен и Сары-Арка – 240 зерен. Масса зерен является определяющим фактором урожайности кукурузы, которая формируется в течение 30 суток в период цветения – созревания зерна. Наибольшая масса зерна с початка, г получена у гибридов Целинный 160 – 131 и у Сары-Арка – 128. Урожайность зерна кукурузы определяется генотипом, средой и эффектами взаимодействия генотипа с окружающей средой. У гибрида Целинный 160 получена наибольшая урожайность зерна – 44 ц/га, средняя урожайность отмечена у гибрида Киз Уракс – 33 ц/га, наименьшая, у гибрида Будан – 30 ц/га, разница со стандартом составила, соответственно: 1, 12 и 15 ц/га. Рекомендуем шире возделывать высокоурожайные раннеспелые гибриды кукурузы: Киз Уракс, Сары-Арка, Целинный 160, Будан в Северном Казахстане как продовольственное, кормовое и семенное зерно.
ECONOMIC-VALUABLE SIGNS OF PERSPECTIVE NUMBERS OF FACULTATIVE SOFT WHEAT
Authors:   LLP «Kazakh Research Institute of Agriculture and Plant Growing», Almalybak village, Almaty region, Kazakhstan, Nurpeisov I.A.
Published: October 2024

Мақала бәсекеге қабілетті сорт сынау питомнигінде (БКССП) факультативті бидай номірлерінің шаруашылыққа-құнды белгілері мен биологиялық қасиеттерін зерттеуге арналған. Нәтижесiнде БКССП факультативтiк бидайдың барлық номірлері өнiп-өсу – масақтану кезеңiнiң ұзақтығы бойынша орташа және орташадан ерте пiсетіндігі (күзгі себісте 169-дан 176-ға күнге дейiн, көктемгі себісте 40-52 күнге дейін) анықталды. Онтөрт номір (Лютесценс 365; 672; 1089; 211, 363, 957, 665; Эритроспермум 629; 333; 305; 1025; 886; 374; 105; 1025 және Ферругиненум 741) сары татқа қарсы иммунитетті көрсетті; 4 номір (Эритроспермум 333, 1025, 374 және Лютесценс 211) жапырақ татына орташа төзімділігімен және 4 номер (Лютесценс 671, 365, 696, 693) сабақтың татына орташа бейімділігімен сипатталды. Дәннің мөлшері (772 – 844 г/л), шыны тәрізділігі (60-тан 78%-ға дейін), қамыры (34,6-дан 51,5%-ға дейін) және ақуызы (15,2-ден 17,2%-ға дейін) сияқты өнім сапасының көрсеткіштері бойынша зерттелген номірлер күшті бидай санатына жатқызылды. Он номір күздік және жаздық себісте де ең жоғары өнімділікпен ерекшеленді: - Лютесценс 957; Лютесценс 693; Эритроспермум 105; Эритроспермум 305; Эритроспермум 629; Лютесценс 365; Лютесценс 696; Эритросперма 886; Эритроспермум 374 және Эритроспермум 507. Олар Қазақстанская 10 стандартымен салыстырғанда күздік егісте 6,2-10,2 ц/га дейін, көктемгі егісте 4,2-7,7 ц/га дейін артық өнімділігін көрсетті. Шаруашылыққа құнды белгілердің жеке көрсеткіштерімен ерекшелінген нөмірлер бидай селекцисында олардың көздері бола алады, ал белгілер мен қасиеттер жиынтығы бойынша іріктелген нөмірлер Қазақстан Республикасының Мемлекеттік сорт сынауына өткізуге керек болашақты жаңа сорттар болып табылады.
Early activation of macrophage-2 with IL-4 in stromal vascular fraction increases VEGF levels and adipocyte count and maintains volume of fat graft in Wistar rats (Rattus norvegicus)
Authors: Vania Rachel , Sanjaya I GPH. , Hamid Agus RRH. , Sudarsa Shita D. , Dewi I GASM. , Niryana I W. , Martadiani Elysanti D.
Published: October 2024

Several previous studies have demonstrated the benefits of early macrophage 2 activation fat grafts supplemented with macrophage culture. However, this approach is considered impractical in clinical settings because of intraperitoneal induction use. The aim of this study was to investigate the effect of early stromal vascular fraction (SVF) macrophage-2 activation with IL-4 on fat graft survival compared to SVF alone using an animal model for better fat graft viability. This experimental study included inguinal fat harvesting, isolated with collagenases to retrieve the SVF, and then injected with a combination of fat graft and SVF (0.3 mL) into the scalp region. The intervention group received an IL-4 intralesional injection on the third day, and the fat grafts were biopsied on days 7, 14, and 30. The primary outcomes were the final volume of the fat graft, vascular endothelial growth factor (VEGF) expression, and the adipocyte cell count using perilipin staining on immunohistochemistry examination. The group receiving IL-4 exhibited significantly higher VEGF on days 7, 14, and 30 (p=0.009, 0.009, and 0.021, respectively). Similarly, the IL-4 treatment significantly increased the perilipin concentration on days 7, 14, and 30 (p=0.008, 0.008, and 0.029, respectively). In this group, VEGF concentration was significantly increased on day 14 as compared to day 7 (p=0.009), while no significant difference was observed in the control group (p=0.090). Additionally, the IL-4 group displayed significantly less reduction of fat graft volume than the control group, as observed on days 7, 14, and 30 (p=0.009, 0.009, and 0.021, respectively). Overall, the study underscores the potential benefits of early M2 polarization in fat grafting, as well as providing practical advantages for improving fat graft volume retention.
Feasibility and pilot study of Indonesia’s first telehealth support program for gynecological cancer survivors undergoing chemotherapy
Authors: Afiyanti Yati , Juliastuti Dyah , So Winnie KW. , Setiowati Retno , Nasution Lina A. , Prawesti Aprilia D.
Published: October 2024

Most Indonesian gynecological cancer survivors experience chemotherapy side effects on their physical and mental health as they face unmet needs of supportive care, which increases the likelihood of discontinuing treatment. Interventions in telehealth assist survivors in resolving these issues. The aim of this pilot study was to determine the feasibility of fighting distress, self-efficacy, health effects, and sexual (FoRSHE-X) interventions and evaluate their potential impact on distress level, side effects knowledge and management, self-efficacy, and sexual quality of life. The study involved gynecological cancer survivors who underwent chemotherapy and participated in ten weeks of individual social media-based education, tele-coaching, and teleconsultations, from September 2023 to June 2024. The study feasibility and pilot outcomes were evaluated using descriptive statistics and qualitative thematic analysis. Of the twelve women recruited, six (50%) completed the study, filled out pre- and post-intervention questionnaires, and participated in interviews. Fifty-four virtual education, coaching, and consultation sessions were performed individually. The statistical results indicated that participants were highly satisfied with the telehealth program, which significantly increased their knowledge (p=0.02), health practices (p=0.04), and self-efficacy (p=0.01). The qualitative analysis highlighted participants' and coaches' perspectives on the study’s acceptance, barriers, and recommendations. In conclusion, this pilot study suggests that a definitive trial to assess the FoRSHE-X interventions is feasible, acceptable, and can be applied not only to gynecological cancer survivors but also to other types of cancer, thereby broadening the potential impact of the study.
Association between vitamin D levels with IL-6 and IL-10 in umbilical cord blood of infants
Authors: Massi Muhammad N. , Fikri Bahrul , Putera Azwin M. , Alfian Sofa D. , Ridha Nadira R. , Putri Sri H. , Chaera Ummi , Iskandar Israini W. , Shimojo Naoki
Published: October 2024

A worldwide issue, vitamin D deficiency affects pregnant mothers and babies everywhere, including Indonesia. It involves the adaptive immune system by controlling the production of pro- and anti-inflammatory cytokines and the balance between humoral (Th2) and cell-mediated (Th1) immunity. The aim of this study was to investigate the relationship between vitamin D and the cytokines IL-6 and IL-10 in infants. It also examined the relationship between ferritin and IL-6/IL-10 in newborns. The study collected 114 umbilical cord blood samples from term-born mothers without clinical symptoms. IL-6 and IL-10 were among the cytokine profiles measured by the enzyme-linked immunosorbent assay (ELISA). SPSS was used for statistical analysis, and an in-silico investigation was carried out to examine the molecular relationships between vitamin D and IL-6/IL-10. Using the 20 ng/mL as the cut-off for vitamin D insufficiency suggested the insignificant association of vitamin D with IL-6 (p=0.42), IL-10 (p=0.76), and ferritin (p=0.47). When the umbilical cord vitamin D level was categorized into four quartiles, the association with the highest statistical significance (quartile 4 versus quartile 2) was observed for IL-6 (p<0.001), IL-10 (p<0.001), and ferritin (p<0.001). However, the linear regression did not suggest the significant correlations of vitamin D with IL-6 (p=0.40) and IL-10 (p=0.45). A significant correlation based on the linear regression was found between ferritin and IL-10 (p=0.03). Molecular docking studies demonstrated binding affinities of -8.04 kcal/mol for IL-6-vitamin D and -8.53 kcal/mol for IL-10-vitamin D complexes, with stable root mean square deviation throughout the simulations. This study contributes valuable insights into the clinical and computational analysis of the relationship of vitamin D with IL-6 or IL-10.
Розвиток креативності здобувачів освіти засобами генеративного штучного інтелекту
Authors: Гуржій Андрій , Бахмат Наталія , Карташова Любов , Зайчук Валентин
Published: October 2024

Наслідки пандемії COVID-19, повномасштабна війна росії проти України, здобуття Україною статусу кандидата на членство в Європейському Союзі актуалізували проблему цифрового та інноваційного розвитку системи освіти. Перехід від традиційної моделі до дистанційної форми навчання зумовив переосмислення ефективності викладацької практики, оновлення освітніх програм та матеріально-технічної бази. Актуальний напрям, що почав розвиватися та використовуватися в українській освіті, – штучний інтелект. Нині освітній процес побудований на використанні цифрових пристроїв та інформаційних технологій. Метою дослідження було проаналізувати використання штучного інтелекту для підтримки розвитку креативності та інновацій в освітньому процесі. Під час аналізу та формування результатів дослідження було використано філософські та загальнонаукові методи. Проаналізовано останні дослідження закордонних науковців та визначено аспекти розглянутої теми, що досі не знайшли відображення в міжнародному дискурсі. Зокрема, у статті розглянуто особливості використання штучного інтелекту в закладах загальної середньої та вищої освіти. Проаналізовано наукові погляди щодо визначення поняття «штучний інтелект» та згідно з цим наведено авторську дефініцію. Розглянуто системи та типи штучного інтелекту загалом та наведено його категорії, що використовуються в освітньому процесі. Наведено приклади використання штучного інтелекту в закладах освіти різного рівня, починаючи із закладів початкової освіти. Визначено перспективи розвитку штучного інтелекту в системі освіти. Практичне значення дослідження полягає в тому, що здійснений аналіз технологій штучного інтелекту в освіті та наведені приклади демонструють можливість їх використання викладачами з метою підвищення зацікавленості здобувачів вищої освіти та ефективності результатів освітнього процесу.
Формування в майбутніх учителів початкових класів системного підходу до впровадження ігрових форм роботи
Authors: Копосов Павло
Published: October 2024

У статті на основі теоретико-методологічного дослідження розглянуто проблему формування системного підходу до організації ігрових форм роботи майбутніми вчителями початкових класів. Проаналізовано поняття «система», «педагогічна система», особливості взаємодії компонентів (елементів) педагогічної системи. Описано системний підхід до аналізу структури ігрової методики та її місце в педагогічній системі вищого порядку. Розкрито вимоги до якостей педагога як організатора навчально-ігрової діяльності молодших школярів. Доведено доцільність формування у майбутніх учителів системного підходу до проведення ігрових форм роботи у практичній педагогічній діяльності.
Підготовка майбутнього вчителя до навчання риторики учнів ліцею з використанням цифрових інструментів
Authors: Кучерук Оксана
Published: October 2024

У статті розглянуто теоретичні і практичні проблеми підготовки майбутніх учителів-словесників до навчання риторики на уроках української мови із використанням цифрових інструментів. За допомогою анкетування майбутніх учителів української мови і літератури (40 осіб) з’ясовано стан готовності їх до навчання риторики учнів. Осмислено досвід професійної підготовки майбутнього вчителя до шкільного навчання риторики в Житомирському державному університеті імені Івана Франка. 
Визначено лінгводидактичні, психолого-педагогічні та цифрові умови підготовки майбутніх учителів-словесників до навчання риторики учнів старших класів. Окреслено методи і цифрові ресурси, що уможливлюють реалізацію відповідних умов на заняттях з риторики і методики навчання української мови в проєкції на навчання риторики учнів старших класів у межах шкільного курсу української мови.
Наголошено на риторичному і лінгвометодичному складниках підготовки майбутніх учителів-словесників до навчання риторики. Акцентовано на особливостях ресурсу «ПАДагогічне колесо» Алана Керрінгтона, механізми функціонування якого базуються, поза іншим, на деталізуванні освітніх цілей, визначенні співвідносних з ними цифрових інструментів та доборі ефективних технологій навчання, які потенційно забезпечують внутрішню мотивацію здобувачів та ефективність освіти. Розглянуто можливості використання цього ресурсу в процесі підготовки майбутніх учителів-словесників до навчання риторики на уроках української мови.
Результати дослідження можуть сприяти кращому усвідомленню системи підготовки студентів-філологів до шкільного навчання риторики з використанням цифрових засобів ІКТ.
Тенденції реалізації компетентнісного підходу в процесі професійної підготовки майбутніх інженерів: науково-дослідницький вимір
Authors: Романчук Наталія , Майборода Олександр
Published: October 2024

У статті розглядається сучасний стан реалізації професійної підготовки майбутніх інженерних фахівців у закладах вищої технічної освіти на компетентнісних засадах. Досліджується проблема формування науково-дослідницьких компетентностей майбутніх інженерів як складової загальної професійної компетентності фахівця технічної галузі. Висвітлюється досвід роботи студентських наукових об'єднань Національного університету кораблебудування імені адмірала Макарова у напрямку формування науково-дослідних компетентностей майбутніх фахівців технічної галузі.
Характеризуються сучасні тенденції, зміст, особливості й мета професійної підготовки майбутніх інженерів у закладах вищої технічної освіти. Професійна компетентність майбутнього фахівця технічної галузі визначається як здатність творчо застосовувати здобуті знання й досвід у практиці виробничого процесу, вміння здійснювати науково-дослідну діяльність у галузі промислового виробництва, виявляти ініціативу в розв’язанні виробничих завдань, здатність організовувати роботу колективу.
Виокремлюється науково-дослідна компетентність як важлива складова професійної компетентності фахівця технічної сфери. Науково-дослідна  компетентність визначається як інтегрована якість особистості майбутнього інженера, здатної до цілеспрямованої наукової, дослідницької діяльності в галузі промислового виробництва на основі сформованих знань, умінь, досвіду та ціннісного ставлення до професії, колег, державних природних ресурсів.
Характеризуються цільовий, мотиваційний, когнітивний, діяльнісний, рефлексивний аспекти науково-дослідної компетентності майбутнього фахівця технічної галузі. Доводиться ефективність залучення майбутніх інженерів до науково-дослідної діяльності з метою формування навичок та досвіду продукування раціоналізаторських, винахідницьких ідей під час розв'язання аналітичних, пошукових, проєктувальних та конструкторських завдань.
CHALLENGES AND SOLUTIONS TO WATER AND SANITATION IN NIGERIA: A REVIEW
Authors: O.O. OKORAFOR, , M.I. CHIKWUE, , B.U. DIKE, , E.U. UJAH,
Published: October 2024

Access to water and sanitation are critical components of public health and socio-economic development, as well as pointers to the fulfilment of Sustainable Development Goal 6 (clean water and sanitation). This review paper presents a critical assessment on the situation and challenges facing access and availability of water/water sources and their sanitary conditions. Considering that Nigeria is the most populated black race, the significant government efforts and international interventions made in the area of water, sanitation and hygiene, many communities are still lacking access to safe water and adequate sanitation facilities. The research observes that about 70% of Nigeria’s population have access to water but more than half of the sources are contaminated thus reflecting the current challenges facing the Nigeria’s water and sanitation sector. Some of the challenges highlighted include overpopulation/urbanization, poor government funding and investment, absence of solid waste management systems, climate change/variability amongst others. Positive recommendations such as investment by government agencies to provide funding, private-public partnerships to enhance/expand existing infrastructure, public awareness on water usage and sanitation and provision of water regulatory frameworks were suggested as possible solutions to the enumerated challenges.
A Future in the Past
Authors: Archer Ben
Published: October 2024

Australia's History educators frequently face challenges regarding the value of post-school qualifications in history. Comments from Australian Government ministers have intensified claims that history degrees lack broad skills valued by employers. This study addresses the dearth of research examining the alignment between learning outcomes from history degrees and occupational skills. A comprehensive analysis was conducted on learning outcomes from 27 history degrees offered by Australian universities. These outcomes were mapped against the Australian Government's Skills Classification Core Competencies and Occupation Listings, employing a rigorous curriculum mapping methodology. The results identified 126 occupations that align with the skills and competencies developed through history degrees. This research not only challenges misconceptions about the employability of history graduates but also provides empirical evidence of the broad applicability of historical skills across various sectors. The findings reveal a significant concentration of history graduates in managerial and professional roles, indicating the high value placed on critical thinking, analytical, and communication skills developed by studying history. However, the study also highlights areas for improvement, particularly in digital engagement and numeracy skills. The research demonstrates that history degrees cultivate a range of transferable skills highly sought after in the modern job market, including advanced communication, critical analysis, research proficiency, and adaptability. These skills position history graduates to excel in diverse fields such as public policy, journalism, law, business, and education. Furthermore, the study underscores the importance of interdisciplinary approaches in curriculum design to enhance graduate employability. This research contributes valuable insights for curriculum development and career guidance in history education, demonstrating that history degrees lead to diverse and meaningful employment outcomes. It also provides a robust evidence base for advocating the value of historical studies in an increasingly skills-focused higher education landscape.
What the Literature Tells Us About the Transition of Second-Career Academics Into Higher Education
Authors: Fellows Ian
Published: October 2024

With the growth and evolution of the higher education sector in recent decades, universities have drawn on more diverse sources from which to recruit academic staff. One such route is for universities to recruit professionals from non-academic backgrounds to teach and research. The transition of career professionals becoming second-career academics is a growing phenomenon, but one that is under-researched in the literature. This paper summarises the findings in the literature on this topic from the last twenty-five years, drawing on forty-four academic articles. Common themes are discussed and presented in a chronological format from the decision-making process prior to transitioning, through the challenges and opportunities commonly experienced by second-career academics making the transition, concluding with a summary of the recommendations presented in the research. In the discussion section that follows, the author draws on their own experience as a second-career academic to summarise pertinent points and offer an additional perspective on the recommendations offered in the literature. The purpose of this article is to offer a summary of what is currently understood in the literature with a view to supporting further research into the transition of second-career academics as an important skills development issue for the higher education sector. The review finds that several recommendations are common in the literature (mentoring schemes, development of academic skills and agency, introduction of reference materials and cultural change) and the viability of these is discussed before recommendations are made for individuals considering transitioning to a career in academia.
Overnutrition among the School Students in Dhaka City: A Cross-sectional Study
Authors: Ahsanul Ashakin Khondaker , Karim Nazmul , Lahiry Sumon
Published: October 2024

Background: The study focuses on childhood obesity and its rise due to fast food and reduced physical activity.Objective: The aim of this study is to investigate the nutritional assessment, knowledge, attitude and practice of English medium School students aged 11-15 years in Dhaka city. Methodology: This cross-sectional study was conducted among randomly selected 280 school students with anthropometric measurement and using a semi-structured questionnaire with the permission of the student’s guardian/s. Results: The overall prevalence of overweight/obesity in this study found 51.43% where 11.43% were obese and 40.0% were overweight. The students have eaten pizza, burger and pastry according to 20%, 28% and 15% respectively at their tiffin time. About 68% respondents have not played any outdoor games (only computer games regularly). 61% normal BMI students did physical activity regularly and 91% risk BMI respondents didn’t physical activity regularly. The energy intake in last 24 hours of respondents according to their BMI also is statistically significant (p<0.01); the average energy intake of 49% male of normal BMI respondent was about 1576 kJ and the average energy intake of 48% female of normal BMI respondent was about 1455 kJ. On the other hand, the average energy intake of 51% male of risk BMI respondent was about 1819 kJ and the average energy intake of 52% female of risk BMI respondent was about 1707 kJ. Conclusion: Overweight/obesity is a public-health concern among English medium school students, especially in high-income group in Dhaka. From the key finding of the current study, awareness program regarding overweight or obesity along with prevention measures were particularly focus on the English medium school students from their school as well as their family.

Keywords: Obesity, Overweight, BMI, Energy Intake, Food consumption, Nutritional value.
An Innovative Logic Model Design to Produce High Performing Public Health Programs: Focus on Need-Based Functional Model for Effective Management of COVID-19
Authors: Kaur Jasleen , Imran Mehak , Gill Yashoodeep
Published: October 2024

Logic models are valuable tools in the field of public health to picturize the relationships between program input, activities and desired outcomes. A logic model provides a clear and seamless method of designing, applying and analyzing public health programs. This article aims at understanding the different types of logic models and their use in different situations by taking into account the pros and cons of each type of model. A specific focus is placed on using Type III Logic model in preventing communicable diseases like Covid-19. This article tries to use this type of logic model in the planning phase to develop programs to address communicable diseases. Public health practitioners, managers and leaders could use this type of model in planning, implementing and evaluating their current and future health promotion and protection programs.

Keywords: Logic model, Public Health Programs, COVID-19
Olanzapine-Induced Weight Gain in A 13-Year-Old Patient with Trichotillomania: A Case Report
Authors: Farhath Juveria
Published: October 2024

Objective: To emphasize a case of olanzapine-induced weight gain in a 13-year-old girl with trichotillomania and discuss the management strategies implemented.
Case Summary: A 13-year-old female diagnosed with trichotillomania experienced significant weight gain after being prescribed olanzapine. The patient also developed increased appetite. Consequently, olanzapine was discontinued and replaced with other antipsychotic agent, alongside lifestyle modifications including diet modifications and regular physical activity.
Conclusion: The case highlights the potential for olanzapine to induce significant weight gain and emphasizes the need for careful monitoring and timely intervention. A shift to safer option and lifestyle changes are essential in managing the patient’s condition.

Keywords: Trichotillomania, Olanzapine, Weight Gain, Paediatrics, Atypical Antipsychotics, Metabolic Effects
Knowledge, Attitude and Practice of Parents to Childhood Immunization: A Cross-Sectional Study in Gandaki Province of Nepal
Authors: Paudel Deepak Raj , Ghimire Gita Devi , Ghimire Amrita
Published: October 2024

Introduction: Childhood immunization is one of the most cost effective public health interventions to prevent vaccine-preventable diseases and improve child survival. In Nepal, the national immunization program aims to ensure that all children receive the recommended vaccines, yet challenges remain in achieving universal coverage. The Knowledge, Attitude, and Practice (KAP) of parents towards immunization play a critical role in vaccine uptake. This study was designed to assess their understanding, attitudes, and behaviors toward vaccinating their children.
Methods: A prospective observational cross-sectional study was conducted from April 22, 2023, to October 2023 GP Koirala National Centre for Respiratory Diseases and Hospital, Tanahun, Gandaki Nepal, involving 227 parents of children under 18 months. The participants were selected through purposive sampling from Pediatric OPD of this hospital. A structured questionnaire was used to collect data about their knowledge, attitude, and practices regarding childhood immunization. The data were analyzed using SPSS version 23 with descriptive statistics, with results expressed as frequencies and percentages and Chi-square tests employed to identify associations between demographic variables and KAP levels.
Results: The study revealed that 73.6% of parents had good knowledge about childhood immunization, recognizing the importance of vaccines and being aware of the vaccination schedule. However, only 64.3% of parents demonstrated a favorable attitude toward immunization, reflecting mixed perceptions about the necessity of vaccines and their safety. Additionally, 60.3% of parents exhibited good practices, indicating that while a majority ensured their children received vaccines, there were still gaps in adherence to the full immunization schedule. Demographic factor such as education level significantly influenced KAP scores.
Conclusion: The study highlights the need for continuous efforts to enhance parental knowledge, improve attitudes, and reinforce good practices regarding childhood immunization in Nepal. Although the majority of parents showed a reasonable understanding of vaccines, the discrepancies in attitudes and practices suggest that targeted interventions, including education and outreach, are necessary to improve vaccination rates. Addressing these gaps is crucial to ensuring complete immunization coverage and safeguarding children from preventable diseases.

Keywords: Childhood immunization, parental knowledge, vaccination practices, public health, vaccine uptake.
Meningkatkan Metode Observasi yang Divariasikan Dengan LKS Word Square pada Materi Klasifikasi Hewan di kelas IX A SMPN 1 Paseh
Authors: Suswandi Ade
Published: October 2024

Berdasarkan hasil penelitian dan pembahasan yang telah diuraikan, dapat diambil Â kesimpulan bahwa melalui metode observasi yang divariasikan dengan LKS Word square pada materi Klasifikasi Hewan di kelas IX A SMP Negeri 1 Paseh, keaktifan dan motivasi belajar siswa serta kinerja guru baik, hal ini dapat meningkatkan hasil belajar siswa dari rata-rata kelas 69,63 menjadi 76, 38 dengan ketuntasan klasikal 77,5% menjadi 87,5%.Berdasarkan hasil Â penelitian Â yang Â telah Â dicapai, Â maka Â dapat Â diberikan saran sebagai berikut: Hendaknya guru biologi menerapkan metode observasi dan LKS Word square pada materi-materi biologi yang lainnya, karena metode observasi yang divariasikan dengan Â LKS Word square memudahkan siswa dalam memahami materi yang dipelajari: PerluÂ  Â dilakukan Â Â sosialisasiÂ  Â terlebihÂ  Â dahuluÂ  Â tentangÂ  Â langkah-langkah pembelajaran Â metode Â observasi Â yang Â divariasikan Â dengan Â LKS Â Word square pada siswa sebelum Â diterapkan dalam pembelajaran agar proses pembelajaran dapat berjalan dengan lancer; Perlu Â manajemen Â waktu Â yang Â baik Â terhadap Â pelaksanaan Â pembelajaran melalui penerapan metode observasi yang dvariasikan dengan LKS Word square Â sehingga Â siswa Â benar-benar Â dapat Â memanfaatkan Â waktu Â untuk berdiskusi dan memahami materi yang dipelajari. Perlu Â diupayakan Â pengelolaan Â kelas Â yang Â baik Â oleh Â guru Â saat Â proses pembelajaranÂ  Â berlangsung Â sehingga Â siswa Â benar-benar Â terlibat Â dalam proses pembelajaran.
Efektivitas Implementasi Pembelajaran Inkuiri Berbasis Kearifan Lokal terhadap Hasil Belajar Siswa
Authors: Purnamasari, S.Pd., M.Pd. Shinta , Wardah Rapa , Diah Tasa
Published: October 2024

Tujuan dari penelitian ini adalah untuk mengetahui efektivitas implementasi model pembelajaran inkuri berbasis kearifan lokal terhadap hasil belajar siswa. Metode penelitian ini menggunakan literature riview atau kajian pustaka dengan 4 langkah literature review. Terdiri dari 7 artikel utama yang terbit dari tahun 2017 sampai 2021 dan dipublikasikan pada berbagai jurnal nasional menjadi bahan kajian Pustaka atau literature review. Hasil penelitian ini menunjukkan bahwa dengan model pembelajaran inkuiri berbasis kearifan lokal dapat meningkatkan berbagai aspek hasil belajar siswa, seperti literasi sains, karakter siswa, keterampilan berpikir kritis, keterampilan berpikir kreatif, higher order thiking skills, dan pemahaman konsep. Peningkatan hasil belajar siswa setelah implementasi pembelajaran inkuiri berbasis kearifan lokal pada ketujuh artikel tergolong ke dalam kategori sedang dan tinggi. Berdasarkan hasil tersebut, dapat dilihat bahwa implementasi pembelajaran inkuiri berbasis kearifan lokal dinilai efektif dalam meningkatkan hasil belajar siswa.
PENINGKATAN HASIL BELAJAR SISWA PADA PEMBELAJARAN IPS MELALUI IMPLEMENTASI METODE RESITASI
Authors: Suharjuddin Suharuddin , Nur Fadilah Dela
Published: October 2024

Penelitian ini bertujuan untuk mengetahui hasil belajar siswa terhadap penerapan metode resitasi pada pembelajaran IPS tema 7 subtema 1 kelas V di SDN Harapan Jaya XVIII. Adapun jenis penelitian ini adalah penelitian kualitatiff dengan pendekatan metode deskriptif kualitatif. Teknik pengumpulan datanya yaitu observasi, dokumentasi, dan  tes tertulis. Hasil penelitian menunjukan Metode Resitasi memiliki respond baik terhadap pemahaman belajar siswa. Hal ini berdasarkan hasil tes sehingga didapatkan beberapa katagori yaitu katagori sangat baik 23%, baik 64%, cukup 3%, dan kurang baik 10% dengan nilai rata-rata 81. Kemampuan kognitif siswa di nilai. Berdasarkan hasil penelitian sebagian besar siswa memiliki hasil yang baik sehingga metode resitasi ini berpengaruh terhadap pemahaman belajar siswa. Hasil tes menunjukan terdapat beberapa katagori yaitu sangat baik 12%,  baik  33%, siswa cukup 15%, dan  kurang baik 40% dengan nilai rata-rata yaitu 72
Stability Studies of Cefuroxime in Peritoneal Dialysis Solution by Using the HPLC Method
Authors: Nosheen Tabassum Nosheen Tabassum , Noor ul Amin Mohsin Noor ul Amin Mohsin , Humna Akram and Muhammad Shan Humna Akram and Muhammad Shan
Published: October 2024

Peritoneal dialysis is a technique for blood purification and is used in chronic kidney disease. Peritonitis is a major problem linked to peritoneal dialysis which limits its utilization. Cephalosporins are extensively used for the treatment of peritoneal dialysis-related peritonitis. Cefuroxime is the second-generation cephalosporin that is used for the prevention and cure of peritonitis. The stability of cefuroxime in peritoneal dialysis solution was investigated after storage at different temperatures. Cefuroxime in different concentrations (250 mg, 750 mg and 1.5 g) was injected into the bags of peritoneal dialysis solution which were stored at 4 oC, 25 oC, and 40 oC. Samples were taken at regular intervals and evaluated by a validated HPLC method. Cefuroxime remained stable for fourteen days at 4 and#176;C and the pattern of stability was the same for all concentrations of cefuroxime. At 25 and#176;C, cefuroxime remained stable for 24 hours in isotonic and hypertonic PD solutions and maintained more than 90% of its initial concentrations. At 40 and#176;C, cefuroxime remained stable for 6.7 and 6.0 hours in isotonic and hypertonic PD solutions respectively. The degradation of cefuroxime was higher in hypertonic solutions as compared to isotonic solutions
Assessment of Critical Quality Attributes of Budesonide and Formoterol Fumarate Dihydrate in Dry Powder Inhalers Marketed in Pakistan
Authors: Affan Ali Affan Ali , Adeel Arsalan Adeel Arsalan , Saif ur Rehman Khattak and Mirza Tasawer Bai Saif ur Rehman Khattak and Mirza Tasawer Bai
Published: October 2024

Dry powder inhalers (DPIs) have been well established and recognized for the delivery to the lungs. It provides better drug stability, less irritable, easy to use with deep penetration of drugs in the lungs. Budesonide (BDS) and formoterol fumarate dihydrate (FFD) indicated in pulmonary diseases.
The main aim of the study is to evaluate BDS, FFD and their marketed DPIs product in Pakistan were compare in quality and performance with the reference product. The particle size distribution and aerodynamic characterization were analyzed by laser diffraction and multi stage liquid impinger, respectively. The particle density and delivered dose uniformity were also determined. HPLC was also used for the qualitative and quantitative estimation of BDS and FFD along with its marketed products.
Laser diffraction particle size analyzer revealed Dv50 53.27 to 56.34 and#181;m having surface area 1815 to 2304 cm3/g. The percentages of emitted dose (%ED) and fine particle fraction (%FPF) was found 98.19 to 99.23% and 31.57 to 34.87%, respectively. The mass median aerodynamic diameter (MMAD) and geometric standard deviation (GSD) were calculated 2.62 to 2.89 and#181;m and 1.99 to 2.54, correspondingly. The quantitative assay of BDS and FFD in all the commercial DPIs and reference product were well within the pharmacopeial limit i.e. 97.26 to 101.36%. The average of ten units results of delivered dose uniformity for BSD and FFD were also found in the range i.e. 97.97 to 103.19% and 98.48 to 104.41 %, respectively.
The results of evaluation of parameters of DPIs like Dv50, %ED, %FPF, MMAD, GSD has shown compliance with the pharmacopeial standards. It is concluded that the all DPIs of BDS/FFD marketed in Pakistan has revealed conformance with the standard of pharmacopoeia and meet the requirements of drug regulatory authority of Pakistan.
Право на публичные акции и свободу слова как факторы обеспечения мандата народного доверия к федеральной власти
Authors: Гуторова Алла Николаевна
Published: October 2024

Конституционный законодатель правомерно противопоставляет организацию публичных мероприятий вне надлежащей организации и мероприятия организованные. Народное доверие к федеральной публичной власти не может быть основано исключительно на бесконфликтном взаимодействии и сотрудничестве. Митинги, демонстрации и иные публичные акции одновременно подтверждают и опровергают народное доверие. В этой связи актуализируется рассмотрение порядка проведения публичных акций, возможностей запрета их проведения и влияния на ограничение прав и свобод человека. Целью настоящей работы состоит в исследовании на основе анализа правовых и доктринальных источников содержания субъективного права на публичные акции и свободу слова в качестве фактора обеспечения мандата народного доверия к федеральной власти. Заявленная цель опосредовала применение как общенаучных методов (диалектический, логический), так и специальных методов (аксиологический и формально-юридический). Сделаны выводы о необходимости изменить механизм проведения публичных акций для легальных политических партий в силу того, что они пользуются поддержкой населения; ввести в чрезвычайных и экстраординарных условиях ряд временных ограничений политических прав и свобод граждан, что не исключает полностью возможность выражения доверия общества к государству, но сокращает формат и полноту их политико-правового взаимодействия.
 
Финансирование: публикация подготовлена в рамках выполнения государственного задания № 085102020-0033 «Трансформация частного и публичного права в условиях эволюционирующих личности, общества и государства».
Концептуальная и институциональная специфика правозащитной деятельности в Российской Федерации
Authors: Позднышов Алексей Николаевич , Москаленко Сергей Григорьевич
Published: October 2024

Правозащитная деятельность в Российской Федерации как функция публичных органов Российской Федерации и как особый тип активности институтов гражданского общества трансформировалась в приоритетный фактор обеспечения стабильности и эффективности развития страны. Основной проблемой, требующей исследования, является корреляция концептуального и организационно-институционального аспектов правозащитной деятельности.  В современном мире в целом и в России в частности со всей очевидностью обнаруживается пробел адекватной новым реалиям концептуальной модификации как доктрины прав и свобод человека, так и адекватных ей институциональных форм кооперации граждан и институтов гражданского общества друг с другом и с государством. В исследование определена специфика современного состояния концепции прав человека в России и ее институционального контекста, выявлены характерные для России сочетание универсализма и регионализма, соотношение иерархии и баланса типов суверенитетов, определены причины доминирования публичного элемента в процессе институционального обеспечения правозащитной деятельности. В результате исследования авторы приходят к выводу, что кризисные процессы в современном мире требуют не отказа от концепции универсальных прав человека, являющейся одним из важнейших достижений цивилизационного развития человечества, а корректировки их концептуальной рецепции в России, определенной модификации их каталога с учетом культурно-исторической самобытности эволюции российской государственности, многовекового государственного строительства, отразившихся и на структурно-институциональной специфике правозащитной деятельности.
Investigating factors associated with operating room nurses’professional transition in Singapore health system
Authors: Ergo Mohamad Azmi Muhammad Kai Ibrahim
Published: October 2024

Background: The nursing workforce in Singapore has been highly depended on foreign nurses to fill its nursing shortfalls. The recent SARS-CoV-2 pandemic has further exacerbated issues of global nursing shortage onto the Singapore nursing workforce. This was reflected by the recent 1,500 healthcare workers, which included nurses, that have left the workforce entirely in the first half of 2021 due to the physical toll such pandemics had on the healthcare workforce. Within the operating room units, similar insights behind the nursing shortfall globally have been discussed in the extant literature. This issues however, lacked exploration in Singapore nursing context. The quintessential question was to understand the associating factors of nursing induction programmes on new nurses transitioning into their operating room unit. Objective: The objective of this study was to investigate factors associated with nursing professional transition in the operating room units in Singapore health system. Design: The research used a cohort study design with a descriptive self-administered quantitative survey administered to obtain data. The researcher developed the self-administered quantitative survey titled the ‘Impacts on Operating Room Nurses with Transitional Support Programmes’survey. Results: At the time of the study, 91 of 96 responses received met the inclusion criteria. Respondents came from across majority of operating room units in Singapore. 75.3% (n = 75) of respondents had worked in their operating room unit for less than two years.13 questions from the self-developed survey were used to identify relationships that existed between variables that affected operating room nurses in Singapore because of the IP they received. The Spearman correlation test reflected 3 majors factors associated with nursing induction programmes on new nurses transitioning in the operating room units. These include lack of adaptation time, facilitators guidance and topic and skills insufficiency leading towards challenges reaching competence. Conclusions: The findings of this quantitative study called for the review of the contents outlined in existing operating room nursing induction programmes in Singapore. While the survey respondents mainly acknowledged that they were satisfied with their orientation programmes, responses in the survey outlined those nurses’ faced challenges with knowledge and skills acquired during their induction programme that affected their initial transition to practice in the operating room.
A Study to assess the Effectiveness of planned Teaching Programme on knowledge regarding specific Learning Disabilities in children among Primary School Teachers at selected Schools, Dharwad District Karnataka, India
Authors: Hampasagar Shivashankar , Akalad Somashekhar , Ramadurg H. B.
Published: October 2024

Nowadays children are day after today’s citizens. they're in a non-stop system of growth and improvement. Any alteration in its direction leads to developmental problems. specific studying incapacity plays a considerable position as silent handicap amongst children. it is expected that four-5% of college students in primary faculty have unique mastering disability. unique studying disability is “A disorder that affect people’s potential to either interpret what they see and listen or to link records from exceptional components of the brain. Such problems volume to high school work and may impend learning to study, write or mathematic’’. As there aren't any precise test to discover kids with precise studying incapacity, fitness specialists must rely mainly on number one faculty teachers report for its prognosis. preceding research have proved that trainer’s understanding towards such youngsters have exquisite influence closer to their restoration. An evaluative study turned into carried out 60 primary faculty teachers at decided on schools, Dharwad district. opportunity; simple random sampling method become used to choose the pattern and become collected through based know-how questionnaire. The studies design used for the look at quasi-experimental: unmarried organization pre-check put up-test design. records evaluation changed into achieved by means of using descriptive and inferential information. universal result of the observe revealed that the extent of knowledge on unique mastering disabilities in youngsters in pre-test revealed that the pre-take a look at suggests that Majority 30(50%) of the respondents had insufficient level of expertise and followed by 18(30%) of the respondents had moderate level of information and Minority 12(20%) had adequate expertise. all through the publish-take a look at indicates that Majority 36 (60%) of the respondents had good enough degree of knowledge and accompanied through 14(23.33%) of the respondents had mild degree of know-how and Minority 10(16.66%) had insufficient knowledge. calculated paired ‘t’ fee (t cal = 20.91) is more than tabulated price (t tab= 2.0096). there may be no considerable affiliation between selected socio-demographic variables. The look at concluded that the deliberate coaching programme was powerful in enhancing know-how concerning specific studying disabilities.