bluuebunny/crossref_metadata_2025 huggingface dataset:
Adult-Specific Life Outcomes of Cleft Lip and Palate in a Western Australian Cohort
Authors: Nicholls Wendy , Harper Craig , Robinson Suzanne , Persson Martin , Selvey Linda
Published: April 2018

Background:

People with a cleft of the lip and/or palate (CL/P) differ from their peers due to their facial appearance, hearing and speech difficulties, and the significant time spent attending appointments and recovering from surgical interventions. These differences may impact life outcomes including occupation, income, education, relationships, psychosocial health issues, and lifestyle choices.

Methodology:

A self-administered questionnaire was posted to 338 former and current patients of the Cleft Lip and Palate Unit of Princess Margaret Hospital (PMH), Perth, Western Australia.

Results:

Completed questionnaires were returned by 158 former and current patients. In comparison to the Australian Bureau of Statistics, study participants attained equivalent highest education levels, full-time annual income levels, occupational categories, employment rates, and home ownership levels. They did not marry later and demonstrated positive health–related lifestyle behaviors. However independent living was significantly delayed, and the number of romantic relationships, marriages, and children was lower, with separation/divorce rates also being lower. A key finding was that 78% of participants self-reported that they experienced at least 1 psychosocial health issue and more than half experienced anxiety and/or depression.

Conclusion:

When comparing the sociological outcomes for the study participants, the psychosocial outcomes were the areas of most concern. Further investigation is required to determine the causes for the high self-reported rates of anxiety and/or depression found in this study.
Synchronous Pancreatic Serous Cystic Neoplasm and Duodenal Neuroendocrine Tumor: Case Report and Review of the Literature
Authors: Madelung Ann Brinch , Detlefsen Sönke
Published: April 2018

Simultaneous presence of pancreatic serous cystic neoplasms and neuroendocrine neoplasms is rare. We present a case with the incidental finding of a duodenal neuroendocrine tumor (NET) with 2 lymph node metastases in a Whipple resection specimen performed to remove a pancreatic cystic neoplasm that postoperatively turned out to represent a serous cystic neoplasm (SCN). The patient was a 75-year-old female. She presented with loss of appetite and weight. Preoperative contrast-enhanced computed tomography scan of the abdomen showed a multicystic lesion in the head of pancreas. On histologic examination of the resection specimen, a pancreatic SCN was found, and in addition in 2 peripancreatic lymph nodes, metastases from a NET. Further examination of the resected specimen revealed a duodenal NET. Review of the literature revealed only one prior study with 4 cases of pancreatic SCN associated with a duodenal NET. In 1 of the 4 cases, the patient had von Hippel-Lindau disease. Our report emphasizes the importance of careful examination of pancreatic resection specimens including the peripancreatic lymph nodes also when dealing with SCNs, as coexisting and more malignant tumors may otherwise be missed.
Social Media in Australian Federal Elections: Comparing the 2013 and 2016 Campaigns
Authors: Bruns Axel , Moon Brenda
Published: April 2018

Against a backdrop of substantial and persistent disruption in Australian federal politics, this article examines the uses of Twitter in campaigning in the 2013 and 2016 federal elections. We comprehensively tracked the tweets posted by, and directed at, all candidates during the final 2 weeks of these campaigns, and compare patterns in candidate and audience activity across the two elections. This documents considerable shifts in campaigning strategies, electorate responses, and central themes of the debate from 2013 to 2016; we show that these shifts are in line with the changing electoral fortunes of Australia’s major party blocs during an exceptionally tumultuous period in federal politics.
Strong scaling for numerical weather prediction at petascale with the atmospheric model NUMA
Authors: Müller Andreas , Kopera Michal A , Marras Simone , Wilcox Lucas C , Isaac Tobin , Giraldo Francis X
Published: April 2018

Numerical weather prediction (NWP) has proven to be computationally challenging due to its inherent multiscale nature. Currently, the highest resolution global NWP models use a horizontal resolution of 9 km. At this resolution, many important processes in the atmosphere are not resolved. Needless to say, this introduces errors. In order to increase the resolution of NWP models, highly scalable atmospheric models are needed. The non-hydrostatic unified model of the atmosphere (NUMA), developed by the authors at the Naval Postgraduate School, was designed to achieve this purpose. NUMA is used by the Naval Research Laboratory, Monterey as the engine inside its next generation weather prediction system NEPTUNE. NUMA solves the fully compressible Navier–Stokes equations by means of high-order Galerkin methods (both spectral element as well as discontinuous Galerkin methods can be used). NUMA is capable of running middle and upper atmosphere simulations since it does not make use of the shallow-atmosphere approximation. This article presents the performance analysis and optimization of the spectral element version of NUMA. The performance at different optimization stages is analyzed using a theoretical performance model as well as measurements via hardware counters. Machine-independent optimization is compared to machine-specific optimization using Blue Gene (BG)/Q vector intrinsics. The best portable version of the main computations was found to be about two times slower than the best non-portable version. By using vector intrinsics, the main computations reach 1.2 PFlops on the entire IBM Blue Gene supercomputer Mira (12% of the theoretical peak performance). The article also presents scalability studies for two idealized test cases that are relevant for NWP applications. The atmospheric model NUMA delivers an excellent strong scaling efficiency of 99% on the entire supercomputer Mira using a mesh with 1.8 billion grid points. This allows running a global forecast of a baroclinic wave test case at a 3-km uniform horizontal resolution and double precision within the time frame required for operational weather prediction.
Optical coherence tomography angiography in age-related macular degeneration: The game changer
Authors: Lupidi Marco , Cerquaglia Alessio , Chhablani Jay , Fiore Tito , Singh Sumit Randhir , Cardillo Piccolino Felice , Corbucci Roberta , Coscas Florence , Coscas Gabriel , Cagini Carlo
Published: April 2018

Optical coherence tomography angiography is one of the biggest advances in ophthalmic imaging. It enables a depth-resolved assessment of the retinal and choroidal blood flow, far exceeding the levels of detail commonly obtained with dye angiographies. One of the first applications of optical coherence tomography angiography was in detecting the presence of choroidal neovascularization in age-related macular degeneration and establishing its position in relation to the retinal pigmented epithelium and Bruch’s membrane, and thereby classifying the CNV as type 1, type 2, type 3, or mixed lesions. Optical coherence tomography angiograms, due to the longer wavelength used by optical coherence tomography, showed a more distinct choroidal neovascularization vascular pattern than fluorescein angiography, since there is less suffering from light scattering or is less obscured by overlying subretinal hemorrhages or exudation. Qualitative and quantitative assessments of optical coherence tomography angiography findings in exudative and nonexudative age-related macular degeneration have been largely investigated within the past 3 years both in clinical and experimental settings. This review constitutes an up-to-date of all the potential applications of optical coherence tomography angiography in age-related macular degeneration in order to better understand how to translate its theoretical usefulness into the current clinical practice.
Building community through song: The therapeutic hospice choir
Authors: Gosine Jane , Travasso Ray
Published: April 2018

Music enables us not only to reflect upon the world in which we live but also to become active agents in creating and shaping it and ourselves. The Treehouse Choir is an innovative, therapeutic programme open to all adult service users and staff at one of the East Anglia’s Children’s Hospices. The target group of the choir membership focuses primarily on the mothers of children receiving care at the hospice and bereaved mothers. The choir addresses the need for psychosocial support for families as they face the challenges of caring for a child with life-limiting and complex health conditions, as well as families mourning the loss of a child. This article analyzes data collected from questionnaires and interviews referring to the emotional, psychological and social benefits of participation in the choir. It examines how singing in the choir serves as a means through which individuals form a community built on shared life experiences, bridging boundaries between service provider and service user, creating a means of self-expression, and breaking down barriers to enable new lines of communication within a non-threatening environment. It also examines the role of public performances in promoting greater awareness of the services provided by the hospice.
Political elites and journalistic practices in India: A case of institutionalized heteronomy
Authors: Maheshwari Swati , Sparks Colin
Published: April 2018

The national elections in India in 2014 that swept the controversial leader Narendra Modi to power have generated a great deal of scholarship on their transformative impact with regard to the Indian polity. This article argues that, in fact, the elections demonstrate a continuity in the media’s relationship with dominant members of the political elite. Favourable, partisan reporting of dominant figures or families has a long history in India since the journalistic field reorients its subservience towards the new power structure. This research examines the similarities and differences in how authoritative and populist leaders like the Gandhis and Modi manipulate media power. While scholars have noted a close correspondence between politics and media in India, there is a research deficit in the analysis of the architecture of the media’s subservience to selected members of national significance, in the world’s largest democracy. This research draws into dialogue two influential theories – Field and New Institutionalism theory – to assert that the natural state of the Indian journalistic field is heteronomy in its relationship with hegemonic members of the political elite. This is occasionally pierced by limits imposed by populist politics in an electoral democracy. The relationship between the news media and individuals of the political elite, thus, can be conceptualized as that of contingent heteronomy.
Institutional Arrangements and Political Shifts in Curitiba, Brazil: A Comparative Analysis of the 2004 and 2014 Master Plans
Authors: Follador Débora , Duarte Fábio , Carrier Mario
Published: April 2018

In theory, shifts in institutional arrangements result in new public policies. This articles focuses on Curitiba, Brazil, an international flagship city of urban planning recognized for its technocratic government. The 2012 municipal elections and the 2013 nationwide political upheaval led to a change in the city's institutional arrangement. As a consequence, the 2014 Master Plan was conceived with the tagline of more public participation. This paper analyzes whether the changes in institutional arrangements influenced the city's planning process and the Master Plan.
Alternative Medicine in North America: A Christian Pastoral Response
Authors: Warren E. Janet
Published: April 2018

Complementary and Alternative Medicine is popular among North Americans. However, there are many areas of concern, both scientific and spiritual, about its appropriate use. Those involved in pastoral care may be consulted for advice and therefore should be knowledgeable about Complementary and Alternative Medicine. This paper reviews and evaluates it from a Christian perspective, and offers suggestions for a pastoral response.
Transforming Chaplaincy Requires Transforming Clinical Pastoral Education
Authors: Ragsdale Judith R.
Published: April 2018

Clinical Pastoral Education (CPE) is a process focused on developing students' personal integration. Outcomes for CPE need to expand to reflect current research in religion and spirituality because religion and spirituality impacts coping, meaning making, decision-making, and health care outcomes. Focusing CPE outcomes on religious/spiritual beliefs and practices used by patients will equip chaplains to provide research-informed spiritual care for families and discipline-specific information for the interdisciplinary team.
Random traveling wave pulse-coupled oscillator algorithm of energy-efficient wireless sensor networks
Authors: Al-Mekhlafi Zeyad Ghaleb , Hanapi Zurina Mohd , Othman Mohamed , Zukarnain Zuriati Ahmad , Shamsan Saleh Ahmed M
Published: April 2018

Energy-efficient pulse-coupled oscillators have recently gained significant research attention in wireless sensor networks, where the wireless sensor network applications mimic the firefly synchronization for attracting mating partners. As a result, it is more suitable and harder to identify demands in all applications. The pulse-coupled oscillator mechanism causing delay and uncharitable applications needs to reduce energy consumption to the smallest level. To avert this problem, this study proposes a new mechanism called random traveling wave pulse-coupled oscillator algorithm, which is a self-organizing technique for energy-efficient wireless sensor networks using the phase-locking traveling wave pulse-coupled oscillator and random method on anti-phase of the pulse-coupled oscillator model. This technique proposed in order to minimize the high power utilization in the network to get better data gathering of the sensor nodes during data transmission. The simulation results shown that the proposed random traveling wave pulse-coupled oscillator mechanism achieved up to 48% and 55% reduction in energy usage when increase the number of sensor nodes as well as the packet size of the transmitted data compared to traveling wave pulse-coupled oscillator and pulse-coupled oscillator methods. In addition, the mechanism improves the data gathering ratio by up to 70% and 68%, respectively. This is due to the developed technique helps to reduce the high consumed energy in the sensor network and increases the data collection throughout the transmission states in wireless sensor networks.
Hardware-in-the-loop validation of speed synchronization controller for a heavy vehicle with Hydraulics AddiDrive System
Authors: Song Dafeng , Li Lixin , Zeng Xiaohua , Li Sheng , Li Guanghan , Li Gaozhi , He Hui , Li Xianghua
Published: April 2018

A novel Hydraulics AddiDrive System consisting of a variable displacement pump and two in-wheel motors is presented. The new Hydraulics AddiDrive System installed on the front axle of a traditional rear-wheel drive heavy vehicle aims to offer better mobility and improve traction efficiency in rough driving condition. To synchronize speeds between front in-wheel motors and rear wheels for optimal traction efficiency, a speed synchronization controller composed of feedforward and feedback control strategy is proposed for displacement adjustment of the variable displacement pump. The feedforward strategy is designed based on the relationship between the displacement coefficients of variable displacement pump and the gears. The feedback strategy utilizes proportional–integral algorithm to correct the dynamic errors. The compound speed synchronization controller helps to improve the control accuracy and adaptability under varied external conditions. Simulations are conducted on AMESim and MATLAB/Simulink to validate the proposed control strategy. The hardware-in-the-loop test allows for a more realistic evaluation of the proposed strategy, providing guidance of its application in real vehicle. Simulation and experiment results indicate that the maximum gradeability and traction force can be separately increased by 14.4%–17.2% and 13.4%–15.6% at low adhesion coefficient roads. The speed of front and rear wheel can be matched accurately with small difference below 1.31%.
Numerical investigation of buoyancy and thermal radiation effects on a mid-/large-sized low NOx combustion system with flue-gas internal recirculation
Authors: Kwon Minjun , Nguyen Ba Hieu , Kim Sewon , Kim Yongmo , Park Jae Hyun
Published: April 2018

Due to stringent regulations, there has been considerable effort to reduce NOx emissions. In this study, we numerically investigate the details of NOx reduction in a mid-/large-sized combustion system employing a new novel flue-gas internal recirculation burner is thoroughly studied with emphasis on the effects of buoyancy and thermal radiation. The NOx emission in the flue-gas internal recirculation combustion system is observed to be half the value in the non-flue-gas internal recirculation system due to lowered temperature. The present combustion system is large enough for the natural convection to be established and as a result the buoyancy effects become remarkable even though the fuel and air are introduced in the transverse direction. Interestingly, the buoyancy augments the NOx formation in the non-flue-gas internal recirculation system, whereas it reduces the NOx emission in the flue-gas internal recirculation system. Contrary to the thermal radiation, the buoyancy effects in large-sized combustion systems have not been systematically studied yet. Also, the numerical prediction of NOx emission with computational fluid dynamics is accurate only when the buoyancy and thermal radiation are considered together. The present finding about NOx emission, buoyancy, and thermal radiation is expected to be very useful in innovating the ultra-low NOx combustion systems.
Authoritarian communication on social media: The relationship between democracy and leaders’ digital communicative practices
Authors: Bulovsky Andrew
Published: April 2018

This research considers authoritarian leaders’ communicative practices on Twitter relative to their democratic counterparts. After a quantitative analysis of 144 world leaders’ Twitter accounts, this study identifies a positive and statistically significant relationship between a country’s level of democracy and its leader’s (1) average number of tweets per day and (2) proportion of tweets that are replies to other users. Additionally, qualitative case studies of Russia, Turkey, and Estonia reveal that authoritarian leaders’ accounts are of a relatively lower quality. Namely, they follow a less diverse set of accounts, have a higher proportion of inactive followers, and tend to tweet projections of power over policy statements. Ultimately, these results reveal an authoritarian preference for uni-directional communication and a democratic preference for multi-directional communication—a stylistic difference partially attributable to stronger incentives from political power structures in general and competitive elections in particular in democratic regimes.
Combination of immunotherapy with chemotherapy and radiotherapy in lung cancer: is this the beginning of the end for cancer?
Authors: Lazzari Chiara , Karachaliou Niki , Bulotta Alessandra , Viganó Mariagrazia , Mirabile Aurora , Brioschi Elena , Santarpia Mariacarmela , Gianni Luca , Rosell Rafael , Gregorc Vanesa
Published: April 2018

Immune checkpoint inhibitors have significantly improved overall survival with an acceptable safety profile in a substantial proportion of non-small cell lung cancer (NSCLC) patients. However, not all patients are sensitive to immune checkpoint blockade and, in some cases, programmed death 1 (PD-1) or programmed death ligand 1 (PD-L1) inhibitors accelerate tumor progression. Several combination strategies are under evaluation, including the concomitant or sequential evaluation of chemotherapy or radiotherapy with immunotherapy. The current review provides an overview on the molecular rationale for the investigation of combinatorial approaches with chemotherapy or radiotherapy. Moreover, the results of completed clinical studies will be reported.
Comparison of Two Music Training Approaches on Music and Speech Perception in Cochlear Implant Users
Authors: Fuller Christina D. , Galvin John J. , Maat Bert , Başkent Deniz , Free Rolien H.
Published: April 2018

In normal-hearing (NH) adults, long-term music training may benefit music and speech perception, even when listening to spectro-temporally degraded signals as experienced by cochlear implant (CI) users. In this study, we compared two different music training approaches in CI users and their effects on speech and music perception, as it remains unclear which approach to music training might be best. The approaches differed in terms of music exercises and social interaction. For the pitch/timbre group, melodic contour identification (MCI) training was performed using computer software. For the music therapy group, training involved face-to-face group exercises (rhythm perception, musical speech perception, music perception, singing, vocal emotion identification, and music improvisation). For the control group, training involved group nonmusic activities (e.g., writing, cooking, and woodworking). Training consisted of weekly 2-hr sessions over a 6-week period. Speech intelligibility in quiet and noise, vocal emotion identification, MCI, and quality of life (QoL) were measured before and after training. The different training approaches appeared to offer different benefits for music and speech perception. Training effects were observed within-domain (better MCI performance for the pitch/timbre group), with little cross-domain transfer of music training (emotion identification significantly improved for the music therapy group). While training had no significant effect on QoL, the music therapy group reported better perceptual skills across training sessions. These results suggest that more extensive and intensive training approaches that combine pitch training with the social aspects of music therapy may further benefit CI users.
Model-based radiation pattern correction for interferometric redatuming in 4D seismic
Authors: Zhao Yang , Li Weichang
Published: April 2018

Interferometric virtual source (VS) redatuming converts surface-triggered source records into the equivalent records as if they originated from buried receiver locations by crosscorrelating downgoing waves with the corresponding upgoing waves. The theory suggests that when the receivers are surrounded by an enclosing boundary of sources, then the VS has an isotropic radiation pattern and yields an accurate response. The resultant records should determine improvement in the seismic repeatability and image quality compared with non-VS. However, in the presence of a complex near surface, an intricate shallow structure and highly variable weathering layers can severely distort the raypath, such that it produces uneven angle coverage to the buried VS. In addition, near-surface reverberations, surface multiples, and other mode-converted waves may leak into the time-gated early arrivals and further corrupt the direct wavefields. The above-mentioned issues can result in distorted radiation patterns and contaminated responses of the VS. We address these issues explicitly by spatially filtering the potentially contaminated direct wavefields using a zero-phase matched filter, such that the filtered wavefield is consistent with a model-based ideal direct P-wavefield observed at common receiver locations. This ideal reference response is computed from a homogeneous approximation to the local near-surface overburden on top of each VS. The phases of the original direct arrivals are preserved. Components associated with the reverberations and other noises can be effectively suppressed as their spatial radiation patterns deviate from that of the ideal single P-wave mode. Toward an isotropic radiation pattern by the iterative matched filter, we reduce the unbalanced illumination arising from imperfect source coverage and near-surface complexity. Compared with previous methods, the new VS approach provides significantly improved image quality and repeatability based on a pilot field of 13 time-lapse surveys, which solved a significant repeatability problem across a 17 month survey gap.
Seismic azimuthal anisotropy study of the Lower Paleozoic shale play in northern Poland
Authors: Cyz Marta , Malinowski Michał
Published: April 2018

We have developed a case study of amplitude variation with azimuth (AVAZ) analysis applied to quantify the amount of the azimuthal anisotropy present in the Lower Paleozoic shales of the Baltic Basin (northern Poland). The challenges encountered here are related to thin (up to 25 m) deeply buried (approximately 3 km) targets, characterized by a weak average azimuthal anisotropy (1%–2% from cross-dipole sonic data). Synthetic AVAZ modeling confirms the applicability of the method. We used data after full-azimuth angle-domain prestack depth migration (PSDM) processed by a contractor and in-house sectored prestack time migration (PSTM). Application of AVAZ on full-azimuth PSDM data provided results that were further corroborated by the available calibration data. Anisotropy azimuths from AVAZ correlate with natural fracture direction from image logs (x-tended range microimager [XRMI]) interpretation, especially at the wells with only one dominant fracture system present. Fracture strikes inferred from AVAZ also correspond with fracture strikes inverted from the microseismic S-wave splitting analysis. Hudson’s crack densities calculated from the AVAZ anisotropic gradients matched crack densities from cross-dipole sonic as well as followed the same trend as the fracture intensities from XRMI data. Part of the success in this case should be attributed to the high-end processing of the input data because such obvious correlations are absent for AVAZ results on sectored PSTM data.
Blood Pressure Coefficient of Variation and Its Association With Cardiac Surgical Outcomes
Authors: Jinadasa Sayuri P. , Mueller Ariel , Prasad Varesh , Subramaniam Kathirvel , Heldt Thomas , Novack Victor , Subramaniam Balachundhar
Published: April 2018

BACKGROUND:

Multiple studies completed in the ambulatory nonsurgical setting show a significant association between short- and long-term blood pressure variability and poor outcomes. However, perioperative blood pressure variability outcomes have not been well studied, especially in the cardiac surgical setting. In this study, we sought to assess whether systolic and mean arterial blood pressure variability were associated with 30-day mortality and in-hospital renal failure in patients undergoing cardiac surgery requiring cardiopulmonary bypass. Furthermore, blood pressure variability has not been evaluated specifically during each phase of surgery, namely in the pre-, intra- and postbypass phases; thus, we aimed also to assess whether outcomes were associated with phase-specific systolic and mean arterial blood pressure variability.

METHODS:

All patients undergoing cardiac surgery from January 2008 to June 2014 were enrolled in this retrospective, single-center study. Demographic, intraoperative, and postoperative outcome data were obtained from the institution’s Society of Thoracic Surgery database and Anesthesia Information Management System. Systolic and mean arterial blood pressure variability were assessed using the coefficient of variation (CV). The primary outcomes were 30-day mortality and in-hospital renal failure in relation to the entire duration of a case, while the secondary outcomes assessed phase-specific surgical periods. In an effort to control the family-wise error rate, P values <.0125 were considered significant for the primary outcomes.

RESULTS:

Of the 3687 patients analyzed, 2.7% of patients died within 30 days of surgery and 2.8% experienced in-hospital renal failure. After adjusting for significant covariates, we found a statistically significant association between increasing CV for systolic blood pressure (CVSBP) and 30-day mortality and in-hospital renal failure. For every 0.10 increase in CVSBP, there was a 150% increase in the odds of death (odds ratio, 2.50; 95% confidence interval, 1.60–3.92; P < .0001) and there was a 104% increase in odds of experiencing renal failure (odds ratio, 2.04; 95% confidence interval, 1.33–3.14; P = .001). The association with mortality was driven primarily by the prebypass period, because the association between CVSBP and mortality during the prebypass phase was significant (P = .01), and not during the postbypass phase (P = .08). There was no significant association between CV for mean arterial blood pressure and either death or renal failure during any period of surgery, including the bypass phase.

CONCLUSIONS:

Increasing systolic blood pressure variability was associated with 30-day mortality and development of renal failure, with surgery phase-specific relationships observed. Further research is required to determine how to prospectively detect blood pressure variability and elucidate opportunities for intervention.
Dependence of Body Weight on Age for Random-Bred Albino Rat and for Eight Lines of Laboratory Rat: Synthetic Studies of Data from Experimental Works and Nurseries in Aspect of the Relationship with Radiosensitivity. Some Characteristics of Rat Species
Authors: Котеров А. , Koterov A. , Ушенкова Л. , Ushenkova L. , Зубенкова Э. , Zubenkova E. , Вайнсон А. , Vaynson A. , Бирюков А. , Biryukov A. , Самойлов А. , Samoylov A.
Published: April 2018

For random-bred albino rat and for eight most known rat lines (Wistar, Wistar Hannover, Wistar Kyoto, Sprague Dawley, Lewis, Fisher 344, Lister and Long-Evans) a brief review of the origins and features was made, and data on the age–weight dependences in norm obtained from experimental works and presented in the materials of firms and nurseries were analysed. The data extracted from the sources by digitizing the original curves or taken from there from the tables were combined (Mean ± 95% Confidence Intervals), and the values were compared in parallel along the Student’s t-test and the Mann–Whitney U-test.

For half the rat lines (males and females) it was found that the body weight growth in works and nurseries does not coincide (statistically significant or in the form of distinct trends), and the discrepancy can began either from a certain time moment (Wistar Hannover, Sprague Dawley), or almost immediately after birth (Lewis, Long-Evans).

The detected phenomenon has practical significance for the object selection for radiosensitivity investigation. Differences in age at the same weight of animals in the experiment and in nurseries can cause errors in background radioresistance. A review of the studies on dependence of the radiosensitivity on the age of irradiated rats was performed with the reproduction of a number of published data in a graphic form and it was concluded that a mistake in the age of rats even for a few weeks can strongly affect the radiosensitivity. It is noted that the importance of taking into account the body mass index is due to the dependence on it of the mass of internal organs, the magnitude of which is affected, among other things, on the results of internal dosimetry.

Distribution by growth intensity (an age of achievement of weight 200 g) for males is follows: Wistar > Sprague-Dawley = Lister > Long-Evans (from nurseries) > Wistar Hannover > Lewis > Wistar Kyoto > Fisher 344 > Long-Evans (from works) > Wistar from 1906–1932 > random-bred albino.

As a result of the study, standard, tabular growth curves for random-bred rat and eight mentioned rat strains obtained by combining and statistical processing of data from all available sources were also presented. This material continues the traditions of Donaldson’s Tables (H.H. Donaldson, 1915) and the growth standards for laboratory animal lines in work of S.M. Poiley (1972).

The report of the individual data by some characteristics of a rat species is presented: average life expectancy, age and weight for various physiological periods of the development, and also a certain ‘standard’ weight for a rat as a species.
Ecological Tourism in the Region (on the Example of the Pskov Region)
Authors: Николайчук Ольга , Nikolaychuk Olga
Published: April 2018

Ecological tourism is considered as a form of nature-oriented tourism, the purpose of which is the cognition and protection of nature and the environment that does not violate the integrity of the ecological system, the conservation of natural resources and the socio-economic development of tourist areas. Ten problems that restrain ecological tourism in Russia are revealed. For the regional analysis, the Pskov region, rich in tourist and recreational resources, advantageous geopolitical position, bordering the three states with four regions of our country, was chosen. It is especially emphasized that ecological tourism today, being a complex interdisciplinary area, ensures a close intertwining of the interests of tourism and ecology economy, as well as culture and social sphere. Ecotourism appeared at the beginning of the XXI century, but already has an impact on the economies of countries and regions, and also activates the movement for the protection and protection of the environment. In conclusion, it is proposed to pay special attention to such tourism objects as museum-reserves, museum-manors located in the old small towns of the region, which are traditional tourism centers.
Communication Interaction in the Information Account-Analytical System
Authors: Попова Л. , Popova L. , Коростелкина И. , Korostelkina I. , Дедкова Е. , Dedkova E.
Published: April 2018

Innovative economy, digital technologies, information management methods in modern conditions of market relations development determine the vector of the domestic policy of the economic entity — maintenance of efficient functioning, progressive development and growth of competitiveness. The implementation of these directions is provided by the construction of an integrated information accounting and analysis system, the development of communication links within this system, the introduction of digital technologies, accounting and control methods and analytical tools. Acceptance and implementation of justified management decisions is possible in the event that an economic entity will form such a system, taking into account the effective communication interaction of its elements. In the article the authors consider the actual issues of the construction and implementation of the information accounting and analytical system and suggest a model for the communication interaction of its elements. The article was prepared in the course of carrying out research work within the framework of the project part of the state task in the field of scientific activity in accordance with the task No. 26.2758.2017 / 4.6 for 2017-2019. on the topic «The system for analyzing the formation and distribution of the cost of innovative products based on the infrastructure concept».
Disruptive Physician Behavior: The Importance of Recognition and Intervention and Its Impact on Patient Safety
Authors: John Preeti R. , Heitt Michael C.
Published: April 2018

Professional misconduct by physicians is a significant problem with negative implications in the healthcare environment and has been termed “disruptive physician behavior” (DPB) in the United States. In recent years, hospitals and healthcare organizations have begun to better understand and formally address DPB, including its management and repercussions. Policy statements by the Joint Commission and the American Medical Association (AMA) have acknowledged that DPB may pose a threat to patient and provider safety. The purpose of this article is to raise awareness about the etiology of disruptive behavior in physicians, describe the consequences and the need for early recognition, and discuss potential interventions.
Real Life Leader in the Mirror: An Online Undergraduate Leadership Course Assignment
Authors: Odom Summer , McKee Valerie
Published: April 2018

There has been an increased frequency of leadership courses being taught online. Scant research exists that describes effective practices for teaching leader ship online. This application brief describes an assignment, the “Real Life Leader in the Mirror” given to undergraduate students in an online personal leadership course as an end of course final project. In this assignment, students synthesize leadership concepts by comparing and contrasting their personalities, interests, beliefs, and capacities with a leader in the media. Through this assignment, students demonstrated the leadership competency of self-awareness and development. Specifically, students articulated knowledge of self, an understanding of self, the value of understanding self, ability to understand self, and the behavior of actually enhancing their understanding of self through this assignment.
Swarm Intelligence: Establishing Behavioral Norms for the Emergence of Collective Leadership
Authors: McNulty Eric J. , Dorn Barry C. , Goralnick Eric , Serino Richard , Grimes Jennifer O. , Flynn Lisa Borelli , Cheers Melani , Marcus Leonard J.
Published: April 2018

To explicate the qualities of cooperation among leaders and their organizations during crisis, we studied the response to the 2013 Boston Marathon bombings. Through interviews and analysis, we discovered leaders successfully overcame obstacles that typically undermine collective crisis response. Qualitative analysis revealed five guiding behavioral principles that appeared to stimulate effective inter-agency leadership collaboration in high stakes. We draw upon concepts of collective leadership and swarm intelligence to interpret our observations and translate the findings into leader practices. We focus on replicable aspects of a meta- phenomenon, where collective action was greater than the sum of its parts; we do not evaluate individual leader behavior. Our findings provide a starting point for deeper exploration of how to bolster public safety by catalyzing enhanced inter-agency leadership behavior.
Traditional knowledge on the use of local food crops by Togutil Ethnic in Halmahera Island, Indonesia
Authors: TAMALENE M. NASIR
Published: April 2018

Tamalene MN. 2017. Traditional knowledge on the use of local food crops by Togutil Ethnic in Halmahera Island, Indonesia. Asian J Agric 1: 66-72. Food crop is an important component in the life system of Togutil ethnic group in Halmahera Island. The main characteristic of the ethnic is their nomadic life despite the existence of some sedentary groups. Generally, the ethnic consumes wild food plants growing in their natural ecosystem. This paper presents selected result of food crop studies conducted in Halmahera Island Indonesia. The botanical supply of food crops of the ethnic has high usefulness in their social and cultural activities. Data was collected through in-depth interview method to key informants chosen based on purposive sampling. Plant species was identified in the Laboratory of Herbarium Botany Bogoriense of the Biological Research Center of Indonesian Institute of Science (LIPI). 48 species of 23 families of food crops are used by Togutil tribe of Halmahera Island Indonesia. The food crops identified were wild plants of 45.83% growing in bushes habitat and primary forest and cultivated crops of 56.25% planted in the garden and yard. Other uses of the food crops were as medicinal plant of 64.28%, house building of 29.17%, and handicraft and adhesive for animal of 4.17%. In the cultural aspect, food crops were used for hunting ritual, medium of exchange (barter), welcoming guest ritual and traditional ritual. The value of Cultural Food Significance Index (CFSI) in very high significance category was 64.58%, high significance was 27.08%, and low significance and very low significance are 4.16%.
Review: Biology of the commercially used sea urchin Tripneustes gratilla (Linnaeus, 1758) (Echinoidea: Echinodermata)
Authors: TOHA ABDUL HAMID A. , SUMITRO SUTIMAN B. , HAKIM LUCHMAN , WIDODO NASHI , BINUR ROBI , SUHAEMI SUHAEMI , ANGGORO AJI W.
Published: April 2018

Toha AHA, Sumitro SB, Hakim L, Widodo N, Binur R, Suhaemi, Anggoro AW. 2017. Review: Biology of the commercially used sea urchin Tripneustes gratilla (Linnaeus, 1758) (Echinoidea: Echinodermata). Ocean Life 1: 1-10. Tripneustes gratilla is a species of sea urchin in shallow tropical waters. The species is economically and commercially important, has ecological value, and prospects as a biological control agent. It is considered as the commercially traded sea urchin. Overexploitation has caused a sharp decline in T. gratilla populations. Understanding biological aspects of T. gratilla is critical to the sustainable use of this resource in the future.
Threat of blast fishing on coral diversity in Peucang Island, Ujung Kulon National Park, Indonesia
Authors: GUMBIRA RADEN WILLY WIGUNA , RIZKIA FITRI , PRIBADI TRI DEWI KUSUMANINGRUM , HIDAYAT MUHAMMAD SYAEFUL
Published: April 2018

Abstract. Gumbira RWW, Rizkia F, Pribadi TDK, Hidayat MS. 2017. Threat of blast fishing on coral diversity in Peucang Island National Park, Indonesia. Ocean Life 1: 26-31. As a maritime country with high biodiversity, the health of Indonesian coral reefs is of high concern. Coral reef ecosystems are friable, and mortality occurs relatively quickly after disturbance, not only by nature but also by human activities such as fish bombing. Fish bombing is a big issue that has always threatened coral reefs, including in Peucang Island, part of Ujung Kulon National Park, a place that is protected by law to preserve its natural diversity. A study on coral coverage was conducted to observe the condition of corals and related biota in a coral reef ecosystem. Data was collected using Point Intercept Transect method in 2m and 8m depths. The results showed that coral coverage in 8-meter depth is only 44.02 percent of the live coral in 2-meter depth. The reduction in the value of Diversity Indices, Dominance Indices as well as the Evenness Index in all study sites led to low diversity, with no dominance by a particular species at any of the study sites. The results also showed that corals are well distributed in both depths. Over the past three years, the damage to corals in Peucang Island had generally increased by 0.7 percent due to fish bombing activities.
Combining expert knowledge and unsupervised learning techniques for anomaly detection in aircraft flight data
Authors: Mack Daniel L. C. , Biswas Gautam , Khorasgani Hamed , Mylaraswamy Dinkar , Bharadwaj Raj
Published: April 2018

Fault detection and isolation schemes are designed to detect the onset of adverse events during operations of complex systems, such as aircraft, power plants, and industrial processes. In this paper, we combine unsupervised learning techniques with expert knowledge to develop an anomaly detection method to find previously undetected faults from a large database of flight operations data. The unsupervised learning technique combined with a feature extraction scheme applied to the clusters labeled as anomalous facilitates expert analysis in characterizing relevant anomalies and faults in flight operations. We present a case study using a large flight operations data set, and discuss results to demonstrate the effectiveness of our approach. Our method is general, and equally applicable to manufacturing processes and other industrial applications.
Context Analysis of Customer Requests using a Hybrid Adaptive Neuro Fuzzy Inference System and Hidden Markov Models in the Natural Language Call Routing Problem
Authors: Rustamov Samir , Mustafayev Elshan , Clements Mark A.
Published: April 2018

The context analysis of customer requests in a natural language call routing problem is investigated in the paper. One of the most significant problems in natural language call routing is a comprehension of client request. With the aim of finding a solution to this issue, the Hybrid HMM and ANFIS models become a subject to an examination. Combining different types of models (ANFIS and HMM) can prevent misunderstanding by the system for identification of user intention in dialogue system. Based on these models, the hybrid system may be employed in various language and call routing domains due to nonusage of lexical or syntactic analysis in classification process.
Products of Volterra type operators and composition operators between weighted Bergman spaces of infinite order and weighted Bloch type spaces
Authors: Wolf Elke
Published: April 2018

We study the boundedness and compactness of products of Volterra operators and composition operators acting between weighted Bergman spaces of infinite order and weighted Bloch type spaces Bw
.
Orthogonal polynomials with respect to the form u = λ(x – a)–1
ν + δb
Authors: Sghaier Mabrouk
Published: April 2018

We study properties of the form (linear functional) u = λ(x – a)–1
ν + δb
, where ν is a regular form. We give a necessary and sufficient condition for the regularity of the form u. The coefficients of a three-term recurrence relation, satisfied by the corresponding sequence of orthogonal polynomials, are given explicitly. The semi-classical character of the founded families is studied. We conclude by giving some examples.
On the classes of functions induced by irregular Carleman–Vekua equations
Authors: Jikia Valerian
Published: April 2018

In the present paper, special functional spaces are constructed, which are naturally connected with sufficiently wide classes of irregular Carleman–Vekua equations. Their properties used essentially for the investigation of irregular generalized analytic functions, are studied. In constructing these functional spaces, we have to investigate the existence of -primitive functions for special classes.
Kallikrein-related peptidase 7 overexpression in melanoma cells modulates cell adhesion leading to a malignant phenotype
Authors: Haddada Meriem , Draoui Hend , Deschamps Lydia , Walker Francine , Delaunay Tiphaine , Brattsand Maria , Magdolen Viktor , Darmoul Dalila
Published: April 2018

We recently reported that human melanoma cells, but not benign melanocytes, aberrantly express kallikrein-related peptidase 7 (KLK7). Here, we show a KLK7 overexpression-mediated decrease of cell adhesion to extracellular matrix binding proteins, associated with downregulation of α5/β1/αv/β3 integrin expression. We also report an up-regulation of MCAM/CD146 and an increase in spheroid formation of these cells. Our results demonstrate that aberrant KLK7 expression leads to a switch to a more malignant phenotype suggesting a potential role of KLK7 in melanoma invasion. Thus, KLK7 may represent a biomarker for melanoma progression and may be a potential therapeutic target for melanoma.