bluuebunny/crossref_metadata_2025 huggingface dataset:
Common co-morbid conditions associated with type 2 diabetes mellitus
Authors: Shaha Kartick Chanda , Rahman Md Shamsur , Shahnaz Tasmin , Habibunnahar -
Published: January 2020

Objective: The aim of the present study was to find out the common co-morbid conditions associated with type 2 diabetes mellitus.

Methods: A descriptive, cross sectional study was conducted from January 2016 to June 2016 among 300 patients attending at Medicine outpatient department of the Community Based Medical College Hospital and Endocrine outpatient department of the Mymensingh Medical College Hospital after obtaining requisite consent from the patients. Data were collected through the interviewing of the patients. The collected data were entered into the computer and analyzed by using SPSS (version 20.1) to know the common co-morbid conditions associated with type 2 diabetes mellitus. The study was approved by the institutional ethical committee.

Results: In a pool of 300 type 2 diabetics, Most of the patients (57.3%) belonged to the middle age group 41-60 years. More than half of the respondents were female (n=223, 74.3%). Among 300 cases, 188 patients had shown association with different co-morbid conditions. Female patients (77%) suffered from more co-morbid conditions than male patients (23%). Hypertension was the most commonly associated disease (65.42%) with DM.

Conclusion: Most of the diabetic patients have co-morbid conditions. Hypertension was the most commonly associated disease with DM.

Bangladesh Journal of Medical Science Vol.19(2) 2020 p.237-239
3D Computed Tomography (3D-CT) Study of the Mandibular Foramen in Iraqi Adults
Authors: Hasan Haider Ali , AL-Sultani Hassan Faleeh Farhan , Hindy Ahmed , Hameed Hanan Ali , Alam Mohammad Khursheed
Published: January 2020

Purpose: One of the extremely important mandibular anatomical landmarks is the Mandibular Foramen (MF). Knowledge the preciseposition of MF is essentialforramus surgical operations, administration of mandibular local anesthesia, and implants placement. This research was carried out to examine the precise location of MF in addition toevaluate the differences of its position between the right and left sides of the mandible and between males and females.

Materials and Methods: This is a retrospective study based on CT gathered from CT database presented at the Radiology Department, Hospital of Hilla. Subjects were Iraqi adults with no craniofacial abnormalities. A total of 60 head and neck scans were collected. CT images were of high resolution and reconstructed into 3D. Analyses were carried out by using MIMICs v7.0 (Materialised Corporation, Belgium), on each side of the mandible, seven landmarks were chosen to determine the distances from these landmarks to MF.

Results: The descriptive statisticalanalysis containing means, standard deviations, minimum and maximum values for each variable were calculated for right and left mandible separately in addition to males and females.There were no differences noticed between the right and left measurements for both genders. Most males measurements tended to have larger measurements than females.

Conclusion: the MF location was highly variable amongst the Iraqi subjects. In both sides of the mandible, the MF position was more or less symmetrical and its position also displayed evidence of sexual dimorphism.

Bangladesh Journal of Medical Science Vol.19(2) 2020 p.310-314
Dravet Syndrome -A case report from Aseer, Saudi Arabia
Authors: Behir Maryam Mohammed , Saeed Muhammad , Siddiqui Aesha Farheen
Published: January 2020

Dravet syndrome (DS) is an epileptic encephalopathy that presents with protracted seizures in infancy, associated with fever, and frequently categorized as febrile seizure at first presentation. In the second year, myoclonia, atypical absence and complex partial seizures develop. The correct diagnosis of DS and appropriate follow-up are delayed until after appearance of signs of developmental regression in the second year of life. Timely detection and diagnosis of DS followed by management with suitable anticonvulsants and treatment plan may reduce the seizure burden and improve long-term developmental outcome. We present a case of 2 years old female with recurrent attacks of generalized tonic colonic convulsion after 1st febrile convulsion diagnosed as Dravet syndrome. The diagnosis was based on history and gene study (SCN1A).

Bangladesh Journal of Medical Science Vol.19(2) 2020 p.315-318
Response to: Limberg Flap Reconstruction in Treating Sacrococcygeal Pilonidal Sinus
Authors: Hayati Firdaus , Rahim Syed Sharizman Syed Abdul , Ani Mohd Firdaus Che , Zakaria Andee Dzulkarnaen
Published: January 2020

Abstract not available

Bangladesh Journal of Medical Science Vol.19(2) 2020 p.343-344
EFEKTIVITAS MODEL PEMBELAJARAN DIRECT INSTRUCTION UNTUK MENINGKATKAN KETERAMPILAN MEMBATIK PADA SISWA SEKOLAH DASAR DI SANGGAR BATIK CIKADU
Authors: Maarif Minhatul
Published: January 2020

Penelitian ini dilatarbelakangi oleh rendahnya keterampilan membatik siswa sekolah dasar yang mengikuti kegaiatan edutourism pada Seni Budaya dan Keterampilan (SBK) di sanggar batik cikadu tanjung lesung. Berdasarkan data evaluasi program di bulan Juni 2019, mayoritas siswa tidak menikmati proses pembelajaran yang diberikan, bahkan keterampilan siswa setelah mengikuti kelas membatik hanya 12% saja. Padahal, mayoritas siswa sekolah dasar (SD) di Kabupaten Pandeglang mengikuti kelas membatik untuk meningkatkan keterampilan psikomotorik. Oleh karena itu, instruktur di sanggar batik cikadu yang dibantu oleh observer melakukan alternatif pembelajaran dengan menerapkan model pembelajaran direct instruction pada siswa SD kelas 5 (lima) dari 5 (lima) sekolah di Kabupaten Pandeglang dengan jumlah pesertanya sebanyak 50 siswa, tiap-tiap sekolah mengutus 10 siswanya untuk ikut dalam kelas membatik ini. Tujuannya agar sanggar batik cikadu menerapkan model pembelajaran yang tepat, sehingga peserta edutourism memiliki keterampilan membatik yang tinggi. Penelitian ini dilakukan menggunakan penelitian tindakan kelas (PTK) di kelas membatik sanggar batik cikadu tanjung lesung dengan 2 (dua) siklus, masing-masing siklus terdiri dari 2 (dua) pertemuan dengan alokasi waktu 2 x 30 menit. Berdasarkan analisis data hasil penelitian didapat bahwa terdapat peningkatan yang signifikan terhadap setiap siklus. Jika pada siklus I aktivitas instruktur hanya 69,5 %, pada siklus II meningkat secara signifikan menjadi 82%.  Selanjutnya pada aktivitas siswa, jika pada siklus I hanya 33,5% pada siklus II menjadi 80%. Begitupun pada keterampilan membatik siwa, setiap siklus mengalami perubahan. Pada siklus I pertemuan ke-1 sebesar 28,75%, kemudian pada pertemuan ke-2 meningkat menjadi 59,75%. Pada siklus II dipertemuan ke-1 meningkat lagi sebesar 76,75% sedangkan pada pertemuan ke-2 meningkat cukup drastis sebesar 84,75%.  Sehingga dapat disimpulkan bahwa penerapan model direct instruction pada kelas membatik di sanggar batik cikadu untuk kelas 5 (sekoah) dasar efektif untuk meningkatkan keterampilan membatik.
Üç Devirde Bir Muhalif: Halide Edip Adıvar'ın Perspektifinden Türkiye'de Siyasi İktidar(lar) ve Demokrasi Sorunu
Authors: TARHAN Belgin
Published: January 2020

Halide Edip Adıvar, yakın tarihin üç devrine tanıklık eder. 1908 Devrimi ile İttihat ve Terakki Partisi öncülüğünde kurulan parlamenter monarşiye geçilirken, 1923’te Cumhuriyet ilan edilirken ve 1950’de iktidar el değiştirirken dönemin muktedirlerinin yanında ve/veya yakınındadır. Başlangıçta desteğini esirgemediği ancak sonrasında fikri ayrılık yaşadığı iktidarlardan uzaklaşarak, görüşlerini muhalif çizgiden aktarmaya devam eder.Bu çalışmada, üç devrin muktedirleriyle Halide Edip’in arasındaki fikri ayrılığının altında yatan nedenler, otoriteryenlik-demokrasi kavramları altında tartışmaya çalışılacaktır. Çalışmada İttihat ve Terakki ile Cumhuriyetin kurucu iktidarındaki problemlere yer verilmekle birlikte asıl olarak Demokrat Parti iktidarının ilk dönemine (1950-54) odaklanılacaktır. Aynı dönemde DP İzmir bağımsız vekili olarak Meclis’te yer alan Halide Edip’in gözünden otoriterliğin izleri saptanmaya çalışılacaktır.
Writing a Research Article in an Introductory Course
Authors: O'Brochta William
Published: January 2020

How well can students exposed to political science for the first time write a research article? Previous research has introduced selected research article writing skills to students in introductory courses, but has not studied whether students in such courses can produce a full research article. I re-designed an Introduction to Comparative Politics course based on the research article writing process. I hypothesized that students would make major gains in article writing skills and develop proficiency comparable to experienced majors. Using a pre- and post-test design along with rubrics for each research article component, I found support for my hypotheses. Students reported large increases in confidence and ability to handle research article writing tasks as a result of the course and demonstrated proficiency comparable to majors on more than two-thirds of rubric items. I provide some suggestions for ways to implement parts of this course design in traditional introductory course settings.
Current situation and trends of enterprise developments in Ukraine’s advertising market
Authors: Romanova Lidia , Zolotarova Valentina
Published: January 2020

The purpose of the article is to analyze and evaluate the current state of the
domestic market of advertising services, tendencies of development of enterprises
of the advertising sphere of Ukraine. Methodology. The domestic market for
advertising services is quite young because it has actually started its active history
since Ukraine gained independence, which has caused some peculiarities of its
development and formation. As a result, the development of the market and its
representatives has been undulating, yet at a rather dynamic pace compared to the
advertising markets of other countries that have already had many years of
experience and history of operation – during 1991-1993 more than 1000 different advertising campaigns were created in Ukraine. companies, including more than
400 companies have been created in the media. We should also take into account
global trends, especially globalization, the development of information technology
and the Internet, which are also influenced by the domestic advertising market,
which in general have caused dramatic changes in the principles of activity of the
entire existing advertising industry.
In the course of the research were used: general scientific methods, in particular:
systematic approach – to summarize data of the advertising sphere as a whole set
of elements in a set of relations and relations between them; methods of
systematization and forecasting – to determine the general tendencies of development
of advertising sphere of Ukraine and enterprises of advertising sphere of Ukraine.
The general tendencies of development of advertising sphere of Ukraine and
enterprises of advertising sphere of Ukraine are substantiated. The main reasons
that have had an impact and will have an impact on the activity of domestic
advertising companies in the future are identified. The scientific novelty is to
identify the main tendencies in the development of the advertising sphere of
Ukraine and domestic enterprises of the advertising sphere, as well as the factors
that influenced and influence their activity.
The results of the study are aimed at ensuring the quality management of the
activities of advertising companies and ensuring a high level of their competitiveness.
They can be used to refine and / or revise strategic plans for development and
activities, management principles of advertising businesses.
Innovation and investment framework for the development of competitive fisheries and aquaculture
Authors: Vdovenko Nataliia , Pavlenko Maryna , Hryniuk Elena
Published: January 2020

The purpose of the article it consists in the substantiation of innovation and
investment principles of competitive development of fisheries and aquaculture in
order to effectively conduct business in modern economic conditions and to comply
with technological parameters of production, introduce innovations in production,
and economical attitude to fish and water resources. Methodology research consists
in using a combination of methods: economic-statistical, monographic, systemic,
economic-mathematical, abstract-logical and others. The scientific novelty the re-
sults obtained include the introduction of innovative, economically viable and
competitive production technologies based on a scientific approach to organizing
an aquaculture business, namely the ability to quickly and efficiently respond to
external challenges, find a way out of a critical situation and correctly adjust
production plans in accordance with changes in market conditions.
Conclusions. Substantially modern principles of the effective functioning of
fisheries in order to ensure competitive activity. Regulatory tools are proposed to
ensure the profitability of the aquaculture business, which include attracting in-
vestments for the acquisition of capital goods, training specialists and constantly
improving their skills, and ensuring efficient fisheries production in an innovative
economy.
Rural green tourism as a way to increase the competitiveness of
agricultural enterprises
Authors: Zhukovskyi Maksym
Published: January 2020

The purpose of the work. The aim of the study is to find new approaches for
the formation of a successful system of managing the competitiveness of agricul-
tural enterprises, namely, to justify the development of a new direction in the
activities of agricultural enterprises as rural green tourism and its impact on the
level of competitiveness of agricultural enterprises. The methodology of the study
is to apply the historical, logical, systemic methods, as well as the system-activity
approach. The scientific novelty is to justify that achieving of high-level com-
petitiveness of the enterprise is possible when using a system-creative approach to
managing the competitiveness of agricultural enterprises, taking into the account
creative-innovative processes such as opening a rural green tourism as new line of
activity. Conclusions.Thus, opening of a new direction in the activities of agricul-
tural enterprises as rural green tourism will bring positive changes in the effi-
ciency of economic activity, improve the business image, increase the volume of
sales of organic products, increase the level of satisfaction of staff, will promote
the development of the local territorial community and increase the level of com-
petitiveness of the enterprise.
Analysis of the efficiency of the use of fixed assets of agricultural enterprise
Authors: Bunda Olga , Yakimenko Anna
Published: January 2020

The purpose of the article is to analyze the efficiency of use of fixed assets
of an agricultural enterprise. The methodology of the study is to use the following
methods: grouping and comparison of indicators in the horizontal and vertical
analysis, calculating the magnitude of the deviations by years; methods of analysis
of coefficients; summarizing the results. The scientific novelty of the work is to
improve the analysis of the efficiency of use of fixed assets of an agricultural
enterprise. Conclusions. Conducting an analysis of the efficiency of use of fixed
assets of an agricultural enterprise, on the example of “Mria” LLC showed that
fixed assets are not used effectively enough at this enterprise. In order to improve
the efficiency of the use of fixed assets of an agricultural enterprise, it is neces-
sary to free the enterprise from unnecessary machinery and other fixed assets and
to introduce new technologies.
Conceptual model of complete creative management formation of complete human health
Authors: Komar Yuriy , Dubas Rostyslav , Ivanov Alexey
Published: January 2020

The purpose of the study is to substantiate and develop a Conceptual model of
full-fledged creative management of the formation of complete human health. The
authors summarized the theoretical generalization of the category «full human health»
(FHH) showed that its essence is a complete system of universal human five-element
subsystems of different nature, consisting of five levels, ten species and fifty elements
of human health intended for use in any public environment. Methodology. The
theoretical and methodological basis of the study is the attributive (triple) scientific
approach, the method of modeling systems of complete creative management, the
method of structural-linguistic quantification in a complex combination with the
fundamental principles of human health: fullness, well-being and hierarchy. The
aforementioned theoretical and methodological base of the research made it possible
to create, in the format of the Fundamental Model of Full-fledged Creative Management
of the Life of Ukrainian Society, a Conceptual Model of Full-fledged Creative
Management of the Formation of FHH, to characterize its phases, stages of
management, to show the role of the subject of management – the person in the
formation of FHH and to draw appropriate scientific conclusions. The scientific
novelty of the obtained results lies in the creation of the Conceptual model of complete
creative management of FHH as a universal full-fledged model of creative management
in the composition of four horizontal phases and ten vertical stages of control, in
which the set of five-element common human systems of different hierarchical level
and nature on five levels, ten species and fifty elements of the process of forming a
FHH for its use in any society nomu environment. Conclusions. The unique properties
of the conceptual model of full-fledged creative management characterize it as a
modern all-human, full-fledged system of creative management of higher-level
hierarchical puzzle. This necessitates the widespread use of the Conceptual Model in
the basic spheres of human activity for the full management of his health in the
conditions of any social environment, in particular Ukrainian society.
Analytical procedures of activitie of sports enterprises
Authors: Bunda Olga , Olianina Alona
Published: January 2020

The purpose of the article is to carry out analytical procedures of activity of
enterprises in the field of sports and to determine the directions of their development
strategy. The methodology of the study is to use the following methods: grouping
and comparison of indicators in the horizontal and vertical analysis, calculating
the magnitude of the deviations by years; methods of analysis of coefficients;
summarizing the results. The scientific novelty of the work is to improve the
analytical procedures of the activity of enterprises in the field of sports. Conclusions.
The carrying out of analytical procedures of activity of sports enterprises, on the
example of Fit-Uno LLC, showed that this type of activity in Ukraine is extremely
promising. The field of sports is constantly developing and gaining popularity
among the society. In order to better develop the sports sector in Ukraine, it is
necessary to provide additional investment in this field and the interaction of the
authorities, business and public organizations.
ORGANIZATIONAL AND METHODICAL ASPECTS OFCONTRACTUAL PROCESS ACCOUNTING AND ANALYSIS AT THE ENTERPRISE
Authors: Bunda Olga , Lebediev Marko
Published: January 2020

The purpose of the article is to study the organizational and methodologicalaspects of accounting and analysis of the contractual process at the enterprise.The methodology of the study is to use a set of methods: dialectical, statistical,structural-analytical, comparative, generalization. The scientific novelty of thework is to determine the procedures and stages of the contractual process, theapplication of simulation modeling in the formation of accounting system andanalysis of the contractual process at the enterprise. Conclusions. Application ofthe proposed stages and procedures in the contractual process will increase theefficiency of the accounting system and analysis of the contractual process at theenterprise. The use of simulation of accounting and analysis of the contractualenvironment in the proposed areas will increase the effectiveness of forming astrategy for enterprise development.
PR-consulting in the field of micro-fertilizer application for application of micro-fertilizers in agricultural production in Ukraine
Authors: Lokutova Olena , Kashchenko Olena
Published: January 2020

The subject of research is a mix of theoretical and practical aspects of the use
of PR-consulting tools in the application of microfertilizers in agricultural practices.
The purpose of the research is to identify, substantiate and enhance the approaches
to the development of a set of PR consulting of tools as direction agricultural
consulting to strategic promotion of the microfertilizers. The methodology. The
article was written with the use of the following methods: critical analysis,
abstraction, comparison, generalization, deduction and synthesis. This methodological
approach makes it possible to consider and compare modern tools in the system of
development and implementation of effective strategic PR-consulting. The results
of the work. The features of PR-consulting in modern conditions were identified
as an important component of the strategy of promoting these products in the
Ukrainian market. Conclusions. The application of the tools described in the article
will help to increase communication with final consumers, effectively to create
PR-strategies and successfully to promote products in the market, positioning them
according to current consumer needs.
Regulatory aspects of export potential in the agricultural sector of national economy
Authors: Hromozdova Larysa , Martynyuk Olexander , Studennikova Inna , Hromozdov Volodymyr , Maliarevsky Victor
Published: January 2020

The purpose of the article is to study the state of export potential in the
agrarian sector of the Ukrainian economy and to formulate regulatory frameworks
to increase its effectiveness in the content of addressing local and global aspects
of food security. The subject of the study is a set of theoretical, methodological,
scientific-organizational and practical regulatory bases that ensure the increase of
efficiency of utilization of Ukraine’s export potential. The methodological bases
of the study are the dialectical methods of scientific knowledge, the systematic
approach, the fundamental provisions of general economic theory. Analytical,
synthetic and deductive methods are used to solve these problems.The scientific
novelty. For the first time data from the analysis of the share of export of food-
stuffs in the total volume of their production in agro-industrial complex (AIC) and dynamics of import-export of foodstuffs of Ukraine for 2014-2017 are given.Con-
clusions.The article discusses the principles of regulation of export potential in
the agricultural sector of the Ukrainian national economy and outlines the current
state of export-oriented production in the agricultural sector of the national econ-
omy. The article describes the role and necessity of development of export-orient-
ed activity of the agrarian food sector of the national economy in Ukraine and
diversification of its production to the world markets, in favor of solving the
problem of global food security for the population of the whole globe, in accordance
with the estimated forecasts of the UN Food and Agriculture Organization for
2050 (FAO). The study concluded the formation and development of national com-
petitive advantages takes place at three levels (companies, industries, countries)
by maximizing process efficiency and continuous productivity gains. The criterion
base for the performance of export-oriented activities is the introduction of a
system of market and state methods of export promotion and the efficiency of the
institutional environment, which ensures the achievement of sustainable socio-
economic development of the country and food security for the globe as a whole.
Pengaruh Melodic Intonation Therapy terhadap Kemampuan Fungsional Komunikasi pada Pasien Stroke dengan Afasia Motorik
Authors: Rohma Naylil Mawadda
Published: January 2020

Latar Belakang: Afasia adalah kehilangan atau penurunan keterampilan komunikasi dan bahasa yang merupakan akibat dari kerusakan otak (biasanya di belahan otak kiri) dan terjadi pada lebih dari sepertiga orang yang selamat dari stroke.Tujuan: Penelitian ini bertujuan untuk mengetahui pengaruh Melodic Intonation Therapy terhadap kemampuan fungsional komunikasi pada pasien stroke dengan afasia motorik.Metode: metode yang digunakan adalah quasy eksperimen pre and post test dengan desain kelompok kontrol dengan teknik purposive sampling dengan jenis consecutive sampling yang kemudian kelompok intervensi dan kelompok kontrol ditentukan menggunakan simple random sampling. Instrumen yang digunakan untuk menilai kemampuan fungsional komunikasi adalah DFCS (Derby Functional Communication Scale). Responden berjumlah 23 orang (12 kelompok intervensi dan 11 kelompok kontrol. Penentuan afasia motorik menggunakan instrumen TADIR (Tes Aphasia untuk Diagnosis Informasi Rehabilitasi).Hasil: Hasil uji-t independen diperoleh nilai p 0,08 yang berarti tidak ada efek Melodic Intonation Therapy pada kemampuan fungsional komunikasi pada pasien stroke dengan motor afasia. Kata kunci : stroke, afasia motorik, kemampuan fungsional komunikasi, melodic intonation therapy   ABSTRACTIntroduction: Aphasia is a loss or decrease in communication skills and language that is a result of brain damage (usually in the left hemisphere) and occurs in more than a third of people who survive strokeObjective: This study aimed to determine the effect of melodic intonation therapy on the functional ability of communication in stroke patients with aphasia motor.Method: the method used is a quasy experiment pre and post test with control group design with a purposive sampling technique with the type of consecutive sampling which then the intervention group and the control group were determined using simple random sampling. The instrument used to assess the functional ability of communication is DFCS (Derby Functional Communication Scale). Respondents numbered 23 people (12 intervention groups and 11 control groups. Aphasia motor determination using the TADIR (Aphasia Test for Rehabilitation Information Diagnosis) instrument.Results: The independent t-test results obtained p value 0.08 which means there is no effect of melodic intonation therapy on the functional ability of communication in stroke patients with aphasia motor.Conclusion: The role of nurses as collaborators is very important because the knowledge of nurses will help bridge patients with speech therapists in interprofessional collaboration. Nurses can help in the availability of data on stroke patients with motor aphasia and therapy and provide education to the family in fulfilling the functional capabilities of communication communication as a basic human need. Keywords: stroke, motor aphasia, communication functional ability, melodic intonation therapy
Self-care and Related Factors in Hypertensive Patients: a Literature Review
Authors: Rozani Moh
Published: January 2020

Abstract  Background: The practice of self-care for hypertensive patients from previous studies, obtained only using some of the variables related to self-care. Comprehensive self-care practices have not been found from previous studies so that the limitations in accessing and studying the practice of self-care carried out by hypertensive patients have not been fully comprehensive.Objective: Conduct a literature review to find out the variables of self-care practices and related factors that influence them.Methods: Literature search was carried out through CINAHL, DOAJ, and Pubmed databases and obtained 853 research articles and the completing examination of menus in research articles with a total of 538 articles. After that, the criteria and critical review phase were separated using the Joanna Briggs Institute (JBI) format with a total 9 articles carried out in a literature review.Results: Self-care practices have variables that include low-salt diets, reduced caffeine consumption, limiting use tobacco, stress management, physical activity, weight management and increasing compliance with treatment regimens. Factors that influence the practice of self-care include gender, age, martial status, hypertension duration, knowledge, social support, and economic status.Conclusion: Self-care practice can be influenced by a variety of factors so it is suggested that further researchers be able to implement innovation intervention strategies needed to control related factors.  Keywords: Hypertension, Related Factors, Self-care
Persepsi Penyakit Pasien Dengan Ulkus Kaki Diabetik Di Banjarmasin, Kalimantan Selatan, Indonesia
Authors: Tjomiadi Cynthia Eka Fayuning
Published: January 2020

AbstrakLATAR BELAKANG: Tingginya kejadian ulkus kaki diabetik di dunia terutama di Indonesia membawa pertanyaan besar, apa faktor yang menyebabkan fenomena tersebut. Hasil penelitian terbaru menunjukan adanya peranan persepsi terhadap penyakit dapat memoengaruhi signifikansi kejadian ulkus kaki diabetik.TUJUAN: Penelitian ini bertujuan untuk mendeskripsikan bagaimana persepsi penyakit terhadap ulkuk kaki diabetik di Banjarmasin, Kalimantan Selatan, Indonesia.METODE: Studi deskriptif dengan metode cross-sectional dilakukan di poliklinik kaki diabetik Rumah Sakit Umum Daerah Ulin Banjarmasin. Persepsi penyakit diukur dengan menggunakan Brief Illness Perceptions Questionnaire (BIPQ).HASIL: Domain dari perspsi penyakit telah berhasil dideskripsikan. Ulkus kaki diabetik dianggap sebagai penyakit kronis yang akan memberikan dampak besar terhadap kehidupan sehari-hari dan sulit di identifikasi. Kurangnya pemahaman tentang ulkus kaki diabetik juga ditemukan dari hasil penelitian iniKata Kunci: Ulkus Kaki Diabetik, Persepsi Penyakit Perception of Patient's Disease with Diabetic Foot UlcersIn Banjarmasin, South Kalimantan, IndonesiaAbstractBACKGROUND The urgency of the high incidence of Diabetic Foot Ulcer (DFU) around the world especially in Indonesia bring a big question, what are the factor that causes this phenomenon. Evidence from the recent research showed the role of illness perception and its significance on DFU.OBJECTIVE This study aims to describe what are the illness perceptions of patients with DFU in Banjarmasin, South Borneo, Indonesia.METHODS A descriptive cross-sectional study design was used. The DFU patients who required routine follow up in podiatry outpatient department of Ulin General Hospital in Banjarmasin were recruited. The illness perceptions were measured by using Brief Illness Perceptions Questionnaire (BIPQ).RESULTS The mean of the illness perceptions domain has been described. DFU considered as chronic disease which bring a major impact on daily life, difficult to identify. The lack of understanding on DFU also has been endorsed by the participants in this study. Keywords: Diabetic Foot Ulcer, Perception of Disease
Persepsi Kebutuhan Pendidikan Komunikasi dalam Kesehatan
Authors: Nugraha Dyan Fitri , Zulliati Zulliati , Tasalim Rian , Noval Noval , Rahman Faisal
Published: January 2020

Latar Belakang: Komunikasi efektif menjadi hal penting untuk mencapai tujuan terapi. Komunikasi efektif antar profesi kesehatan dan kepada pasien juga dapat mencegah terjadinya medication error. Tujuan: Penelitian ini bertujuan untuk melihat persepsi kebutuhan pendidikan komunikasi bagi mahasiswa kesehatan serta alasan pentingnya pendidikan komunikasi kesehatan.Metode: penelitian ini menggunakan Metode survey yang dilaksanakan secara acak kepada 174 responden yang terdiri dari mahasiswa farmasi, keperawatan, dan kebidanan yang sedang/telah menjalani dinas, praktik kerja lapangan atau magang.Hasil: Hasil penelitian menunjukkan bahwa 99.4% responden memahami pentingnya ilmu komunikasi namun sebanyak 34.7% menyatakan masih kurang mendapatkan ilmu komunikasi dalam perkuliahan. Komunikasi dalam kesehatan harus menjadi kemampuan utama dan harus selalu disertai praktik yang memadai sehingga melatih mahasiswa kesehatan untuk dapat berinteraksi dengan baik kepada pasien atau profesi lain.Kata Kunci: Komunikasi Kesehatan, Komunikasi EfektifPerception of Communication Education Needs in HealthAbstract Background: Effective communication has become an important key in achieving the goal of a therapy. Effective communication, whether it was inter-health proffessions, or between health proffessions and the patients, were also be able to avoid medication errors. Objective: The objective of this study was to review any perceptions of communication education needed for health students, plus the reasons why it was necessary. Methods: Methods used in this study was a randomly conducted survey on 174 respondents consisting of pharmacy, nursing, and midwifery students who were/ had been undergoing any services, field work practices, or internships. Results: The result of this study showed that 99.4% of respondents considered communication education as important, while 34.7% stated their lacking of communication science in class.Conclusion: Health communication should be the main ability and be accompanied with sufficient practice, so that it would train health students to interact well both with patients and other health proffessions. Key Words: Health Communication, Effective Communication
Forecasts of the Amount Purchase Pork Meat by Using Structured and Unstructured Big Data
Authors: Ryu Ga-Ae , Nasridinov Aziz , Rah HyungChul , Yoo Kwan-Hee
Published: January 2020

It is believed that the huge amount of information delivered to the consumers through mass media, including television and social networks, may affect consumers’ behavior. The purpose of this study was to forecast the amount required to purchase pork belly meat by using unstructured data such as broadcast news, TV programs/shows and social network as well as structured data such as consumer panel data, retail and wholesale prices and production outputs in order to prove that mass media data release can occur ahead of actual economic activities and consumer behavior can be predicted by using these data. By using structured and unstructured data from 2010 to 2016 and five forecasting algorithms (autoregressive exogenous model and vector error correction model for time series, gradient boosting and random forest for machine learning, and long short-term memory for recurrent neural network), the amounts required to purchase pork belly meat in 2017 were forecasted and compared with the actual amounts to validate model accuracy. Our findings suggest that when unstructured data were combined with structured data, the forecast pattern is improved. To date, our study is the first report that forecasts the demand of pork meat by using structured and unstructured data.
Reaction of Sweet Maize to the Use of Polyethylene Film and Polypropylene Non-Woven Fabric in the Initial Growth Phase
Authors: Adamczewska-Sowińska Katarzyna , Sowiński Józef
Published: January 2020

Sweet maize (Zea mays L. var. saccharata Bailey) is a valuable vegetable adapted to growing in temperate climate conditions. Temperature, especially in the beginning of the growing period, has a crucial effect on vegetation and yield. The best maize initial growth requires soil temperature above 10 °C. Maize covered by polyethylene film and polypropylene non-woven fabric leads to an increase in temperatures which accelerates crop growth. Three years (2012–2014) of field experiments were carried out at the Research and Didactic Station in Psary, belonging to the Department of Horticulture of Wroclaw University of Environmental and Life Sciences. A three-factorial experiment was established using the randomized subblock method in three repetitions in the years 2012–2014. Cobs were harvested in the milk-dough phase of grain maturity. Hybrid Rustler F1 produced, on average, 35.4% more marketable yield than Signet F1. On average, 10.2% more cobs and 22.7% more cobs (with Hybrid Rustler F1 and Signet F1, respectively) were harvested in cases when the sowing was performed in the third decade of April. The use of covers contributed to a significant increase in the yield compared to the yield of uncovered plants. Transparent foil also contributed to a significant increase in the number of cobs harvested in the marketable yield.
Performance Evaluation of Two Commercially Available Portable Spectrometers to Non-Invasively Determine Table Grape and Peach Quality Attributes
Authors: Donis-González Irwin R. , Valero Constantino , Momin Md Abdul , Kaur Amanjot , C. Slaughter David
Published: January 2020

Near-infrared (NIR) spectroscopy has been used to non-destructively and rapidly evaluate the quality of fresh agricultural produce. In this study, two commercially available portable spectrometers (F-750: Felix Instruments, WA, USA; and SCiO: Consumer Physics, Tel Aviv, Israel) were evaluated in the wavelength range between 740 and 1070 nm to non-invasively predict quality attributes, including the dry matter (DM), and total soluble solids (TSS) content of three fresh table grape cultivars (‘Autumn Royal’, ‘Timpson’, and ‘Sweet Scarlet’) and one peach cultivar (‘Cassie’). Prediction models were developed using partial least-square regression (PLSR) to correlate the NIR absorbance spectra with the invasive quality measurements. In regard to grapes, the best DM prediction models yielded an R2 of 0.83 and 0.81, a ratio of standard error of performance to standard deviation (RPD) of 2.35 and 2.29, and a root mean square error of prediction (RMSEP) of 1.40 and 1.44; and the best TSS prediction models generated an R2 of 0.97 and 0.95, an RPD of 5.95 and 4.48, and an RMSEP of 0.53 and 0.70 for the F-750 and SCiO spectrometers, respectively. Overall, PLSR prediction models using both spectrometers were promising to predict table grape quality attributes. Regarding peach, the PLSR prediction models did not perform as well as in grapes, as DM prediction models resulted in an R2 of 0.81 and 0.67, an RPD of 2.24 and 1.74, and an RMSEP of 1.28 and 1.66; and TSS resulted in an R2 of 0.62 and 0.55, an RPD of 1.55 and 1.48, and an RMSEP of 1.19 and 1.25 for the F-750 and SCiO spectrometers, respectively. Overall, the F-750 spectrometer prediction models performed better than those generated by using the SCiO spectrometer data.
Antibiotic Residues and Antibiotic-Resistant Bacteria in Pig Slurry Used to Fertilize Agricultural Fields
Authors: Rasschaert Geertrui , Van Elst Daan , Colson Lander , Herman Lieve , de Carvalho Ferreira Helena Cardoso , Dewulf Jeroen , Decrop Johan , Meirlaen Jurgen , Heyndrickx Marc , Daeseleire Els
Published: January 2020

Pig manure may contain antibiotic residues, antibiotic-resistant bacteria or pathogens, which may reach the environment upon fertilization. During this study, 69 antibiotic residues belonging to 12 classes were quantified in 89 pig slurry samples. These samples were also studied for the presence of Salmonella and for E. coli resistant to meropenem, colistin, ciprofloxacin, or cefotaxim. The obtained isolates were further tested for antibacterial susceptibility. No antibiotic residues were detected in four samples, whereas in the other samples, up to 12 antibiotics were found. The most frequently detected antibiotic residues were doxycycline, sulfadiazine, and lincomycin. Doxycycline was found in the highest concentration with a mean of 1476 µg/kg manure (range: 18–13632 µg/kg). Tylosin and oxytetracycline were found with mean concentrations of 784 µg/kg (range: 17–5599 µg/kg) and 482 µg/kg (range: 11–3865 µg/kg), respectively. Lincomycin, had a mean concentration of 177 µg/kg manure (range: 9–3154 µg/kg). All other 18 antibiotic residues were found with mean concentrations of less than 100 µg/kg manure. Fifty-one slurry samples harbored Salmonella; 35% of the Salmonella isolates were sensitive to a panel of 14 antibiotics, whereas the other 65% were resistant up to five antibiotics. For E. coli, 52 manure samples contained E. coli isolates which were resistant to ciprofloxacin and 22 resistant to cefotaxime. All ciprofloxacin and cefotaxime-resistant isolates were multi-resistant, with resistance up to nine and eight antibiotics, respectively. This research indicates that pig slurry used for fertilization often contains antibiotic residues and antibiotic-resistant bacteria, including pathogens.
Effects of Early Intervention with Antibiotics and Maternal Fecal Microbiota on Transcriptomic Profiling Ileal Mucusa in Neonatal Pigs
Authors: Xu Rongying , Wan Jiajia , Lin Chunhui , Su Yong
Published: January 2020

This study aimed to investigate the effects of early intervention with antibiotics and maternal fecal microbiota on ileal morphology and barrier function, and transcriptomic profiling in neonatal piglets. Piglets in the amoxicillin (AM), fecal microbiota transplantation (FMT), and control (CO) groups were orally administrated with amoxicillin solution (6.94 mg/mL), maternal fecal microbiota suspension [>109 colony forming unit (CFU)/mL], and physiological saline, respectively. Compared with the CO group, early intervention with AM or FMT significantly decreased ileal crypt depth on day 7 and altered gene expression profiles in ileum on days 7 and 21, and especially promoted the expression of chemokines (CCL5, CXCL9, and CXCL11) involved in the toll-like receptor signaling pathway on day 21. FMT changed major immune activities from B cell immunity on day 7 to T cell immunity on day 21 in the ileum. On the other hand, both AM and FMT predominantly downregulated the gene expression of toll-like receptor 4 (TLR4). In summary, both early interventions modulated intestinal barrier function and immune system in the ileum with a low impact on ileal morphology and development.
Prevalence of Antibiotics Prescription and Assessment of Prescribed Daily Dose in Outpatients from Mexico City
Authors: Sánchez-Huesca Ramiro , Lerma Abel , Guzmán-Saldaña Rebeca M.E , Lerma Claudia
Published: January 2020

Pharmacoepidemiological research about antibiotics is supported by the World Health Organization (WHO), but data regarding antibiotic prevalence based on actual prescriptions and dosing patterns are insufficient. The aims were: (i) To estimate the prevalence and prescribed daily dose (PDD) of antibiotics in outpatients from Mexico City and (ii) to compare the PDD against the defined daily dose (DDD), as established by the WHO. The study included 685 prescriptions of antibiotics selected randomly from five geographical zones of Mexico City. Drug, dose, frequency, and duration of treatment were obtained from each prescription. PDD values of each antibiotic drug were calculated as the average of the daily doses. Sub-use and overuse were determined by the ratio PDD/DDD for each prescription. The most prescribed antibiotics to outpatients from Mexico City included six pharmacological groups: quinolones (28%), penicillins (23%), cephalosporins (17%), macrolides (10%), lincosamides (9%), and sulfonamides (4%). Both overuse and sub-use were high (55% and 63%, respectively). In conclusion, most of the antibiotics with a high prevalence of prescription also had a high rate of either sub-use or overuse, with prescribed doses that significantly differ with their corresponding DDD. The dosing variation has important clinical implications since it denotes low prescription control.
Mitoprotective Clinical Strategies in Type 2 Diabetes and Fanconi Anemia Patients: Suggestions for Clinical Management of Mitochondrial Dysfunction
Authors: Pagano Giovanni , Pallardó Federico V. , Porto Beatriz , Fittipaldi Maria Rosa , Lyakhovich Alex , Trifuoggi Marco
Published: January 2020

Oxidative stress (OS) and mitochondrial dysfunction (MDF) occur in a number of disorders, and several clinical studies have attempted to counteract OS and MDF by providing adjuvant treatments against disease progression. The present review is aimed at focusing on two apparently distant diseases, namely type 2 diabetes (T2D) and a rare genetic disease, Fanconi anemia (FA). The pathogenetic links between T2D and FA include the high T2D prevalence among FA patients and the recognized evidence for OS and MDF in both disorders. This latter phenotypic/pathogenetic feature—namely MDF—may be regarded as a mechanistic ground both accounting for the clinical outcomes in both diseases, and as a premise to clinical studies aimed at counteracting MDF. In the case for T2D, the working hypothesis is raised of evaluating any in vivo decrease of mitochondrial cofactors, or mitochondrial nutrients (MNs) such as α-lipoic acid, coenzyme Q10, and l-carnitine, with possibly combined MN-based treatments. As for FA, the established knowledge of MDF, as yet only obtained from in vitro or molecular studies, prompts the requirement to ascertain in vivo MDF, and to design clinical studies aimed at utilizing MNs toward mitigating or delaying FA’s clinical progression. Altogether, this paper may contribute to building hypotheses for clinical studies in a number of OS/MDF-related diseases.
Cytoprotective Effects of Delphinidin for Human Chondrocytes against Oxidative Stress through Activation of Autophagy
Authors: Lee Dong-Yeong , Park Young-Jin , Song Myung-Geun , Kim Deok Ryong , Zada Sahib , Kim Dong-Hee
Published: January 2020

Antioxidant enzymes are decreased in osteoarthritis (OA) patients, implying the role of oxidative stress in osteoarthritis pathogenesis. The aim of this study was to evaluate the cytoprotective effects of delphinidin, a potent antioxidant, in human chondrocytes and the underlying mechanisms. The cytoprotective mechanism induced by delphinidin against oxidative stress (H2O2) in human chondrocytes was investigated. Cell viability and death were evaluated using proapoptotic and antiapoptotic markers such as cleaved caspase-3 (c-caspase-3), cleaved poly(ADP-ribose) polymerase N-acetylcysteine (c-PARP), Bcl-XL, and transcription factors associated with redox and inflammation regulation, including nuclear factor kappa B (NF-κB) and nuclear factor (erythroid-derived 2)-like 2 (Nrf2). Induction of autophagy was assessed by formation of LC3-II and autophagosome-(LC3 punctate, monodansylcadaverine (MDC) and acridine orange staining) in the presence or absence of an autophagy inhibitor. Treatment with delphinidin itself at concentration below 50 µM for 24 h did not affect viability of chondrocytes. Delphinidin inhibited reactive oxygen species (ROS)-induced apoptosis by significantly decreasing apoptosis markers such as c-caspase-3 and c-PARP while increasing antiapoptotic marker Bcl-XL and antioxidant response NF-κB and Nrf2 pathways. Delphinidin also activated cytoprotective autophagy to protect chondrocytes during oxidative stresses. Activation of autophagy with autophagy inducer rapamycin also inhibited ROS-induced cell death and decreased proapoptotic proteins but increased antiapoptotic protein Bcl-XL, NF-κB, and Nrf2. Delphinidin can protect chondrocytes against H2O2-induced apoptosis via activation of Nrf2 and NF-κB and protective autophagy. Thus, it can inhibit OA with protection of chondrocytes. Delphinidin can protect chondrocytes against H2O2-induced ROS with maintenance of homeostasis and redox. These results suggest that delphinidin could be used to protect chondrocytes against age-related oxidative stress and other oxidative stresses in the treatment of OA. Thus, delphinidin may play a critical role in preventing the development and progression of OA.