bluuebunny/crossref_metadata_2025 huggingface dataset:
TÍNH ARTIN VÀ TÍNH -ỔN ĐỊNH CỦA MÔĐUN ĐỒNG ĐIỀU ĐỊA PHƯƠNG TƯƠNG ỨNG VỚI MỘT CẶP IĐÊAN
Authors: Nam Trần Tuấn , Yến Đỗ Ngọc
Published: December 2021

Khái niệm về môđun -ổn định được đưa ra bởi Tran Tuan Nam trong bài báo (Tran, 2013) và tác giả đã sử dụng nó như một công cụ để nghiên cứu tính biểu diễn được của lớp môđun đồng điều địa phương. Trong bài báo này, chúng tôi sẽ giới thiệu về lớp môđun -ổn định, đây được xem như là một khái niệm mở rộng thực sự từ khái niệm -ổn định. Chúng tôi nghiên cứu tính -ổn định cho lớp môđun đồng điều địa phương theo một cặp iđêan, lớp môđun này đã được chúng tôi nghiên cứu trong (Tran & Do, 2020). Các tính chất cơ bản về môđun -ổn định đã được nghiên cứu và sử dụng nó để nghiên cứu tính artin của lớp môđun đồng điều địa phương theo một cặp iđêan. Hơn nữa, chúng tôi cũng đưa ra mối liên hệ giữa tính artin, tính -ổn định và tính triệt tiêu của lớp môđun đồng điều địa phương theo một cặp iđêan.
Public procurement and Covid-19 in Portugal: the particular case of the acquisition of institutional publicity related to the pandemic disease
Authors: Caldeira Marco
Published: December 2021

In addition to several other exceptional legal measures adopted in regard to public procurement related to the pandemic of the disease Covid-19, the Government also enforced a specific regime for the acquisition of institutional publicity related or associated to Covid-19. However, this framework (set forth in article 2nd-B of Decree-Law no. 10-A/2020, of March 13, added by Decree-Law no. 20-A/2020, of May 6) is highly problematic and raises several issues, as, under the “cover” of a procurement regime, it is actually a direct public subsidization to the social media market, with a full upfront payment based on grounds of “urgency” that does not seem compatible with the public procurement rules.
The transposition of the 2014 EU Directives on public procurement by Portugal: woes and expectations
Authors: Valadares Tavares Luís
Published: December 2021

The new EU Directives on Public Procurement are oriented to promote the application of the concept of strategic public procurement which has been subject to several communications and discussions promoted by the European Commission and European Parliament. This new approach to Public Procurement has deep implications in the legal framework adopted by each Member State as well as in the public administration culture and organization in order that the new objectives of promoting the qualification of markets, the increase of innovation, the respect by social cohesion and environmental sustainability and a better access to public markets by SME’s will be achieved aligned with the UE 2020 Agenda. In this paper, the process and the results of the transposition of this Directives by Portugal are studied not just in terms of the respect for the Directives rules but also considering its likely positive and negative impacts on Portuguese public markets which are also synthetically described herein.
Transposition of the 2014 European Directives on public procurement by France
Authors: Ben Khelil Kawthar
Published: December 2021

The French public procurement code should be published in the next weeks. This project initiated by the French Government gave rise to a public consultation between 23 April and 29 May 2018; it is aimed at grouping together, without any amendments to current rules, all existing provisions relating to public procurement law (all contracts qualifying as public contracts and concessions), according to a consistent plan, in order to make the relevant legal framework clearer and more accessible. As of this day however, French rules relating to the conclusion and performance of public procurement contracts are contained in ordinance (ordonnance) n° 2015-899 of 23 July 2015 relating to public contracts (hereinafter referred to as the “Ordinance”) and its implementation decree (décret), n° 2016-360, of 25 March 2016 (hereinafter referred to as the “Decree”), that have implemented into domestic law the new European directives on public procurement. They entered into force on 1 April 2016. This contribution is aimed at providing an overall presentation of the significant changes resulting from the implementation into French law of EU Directives 2014/24 and 2014/25 without claiming to be exhaustive.
The transposition of the 2014 Directives on public procurement into the Italian law: a challenge for a deep reform of the Italian public procurement system
Authors: Guidi Valentina
Published: December 2021

The transposition of the 2014 Directives on public procurement into the Italian law represented a unique opportunity to introduce an ambitious reform of the Italian public procurement system. A strategic document, issued in 2015 by the Italian Government with the support of the European Commission, provided the main objectives, as pointed out in the EU Directives, and the guidelines of the reform which were first transposed by the Italian institutions into the new legislation on public procurement, the Code of public contracts, in 2016 and are currently being implemented by the different actors involved.
Histopathological profile of women who had previously failed in-vitro fertilization and the association to the outcome in the subsequent in-vitro fertilization cycle
Authors: Steiner Naama , Turki Rola F , El-Khayat Waleed , Malki Ghada Al , Tannus Samer , Dahan Michael H.
Published: December 2021

Objective To evaluate the endometrial histopathological profile of patients undergoing curettage and the association of the histopathological profile with the pregnancy outcome during the subsequent in-vitro fertilization (IVF) cycle.Methods In this retrospective cohort study, a total of 248 women with at least one failed attempt of IVF and who underwent curettage and a subsequent IVF were included. Demographic data, endometrial histopathological records, stimulation information, and pregnancy outcomes were collected and analyzed. Results The histopathological analysis of endometrial tissues showed that 130 women (52.4%) had endometrial pathologies. Of these women, 103 (41.5%) had endometrial polyps, 22 (8.9%) had chronic endometritis, and five (2.0%) had both polyps and endometritis. No statistical difference was observed between the normal histopathology group and the abnormal histopathology group in the outcome of the subsequent IVF cycle. Subgroup analyses were performed to further characterize and compare women with normal histopathology and women with endometrial polyps (polyp subgroup) or chronic endometritis (endometritis subgroup). No statistical differences were found among the three groups in the rates of pregnancy (44.1% vs. 49.5% vs. 45.5%, P=0.72), biochemical pregnancy loss (13.5% vs. 15.7% vs. 20.0%, P=0.86), clinical pregnancy loss (25.0% vs. 31.4% vs. 30.0%, P=0.77), and live birth (27.1% vs. 26.2% vs. 22.7%, P=0.91) during the subsequent IVF cycle.Conclusion Women with previously failed IVF and abnormal endometrial histopathology treated with curettage had the same outcome in the subsequent IVF cycle as women with normal endometrial histopathology.
Remote Reading of Water Meters as an Element of a Smart City Concept
Authors: Cichoń Tomasz , Królikowska Jadwiga
Published: December 2021

The provisions of the European law have defined “Smart Metering” as a tool for remote meter readings and management of energy networks. Currently, after years of research and many real- life applications, it is one of the most popular solutions that defines friendly and modern cities. Similarly to automatic street lights, traffic signals or waste management systems, monitoring and control of water supply and sewage systems significantly improves the quality and comfort of life of city residents. The city infrastructure managers may use it as a tool that primarily allows for some cost savings and better resource management. The paper describes a remote transfer of water meters data through the Internet of Things technology. Also additional options have been presented, which are available once the data on water demand has been acquired. They can be communicated to other clients, e.g. other municipal services, as an element of Smart City, and to the customers. Thanks to this technology, the customers may analyze and better manage their actual water consumption trying to optimize it. Over time, it seems that saving water has become not only a fashionable whim but a trend to stay.
Reconstruction of the Islamic Education Paradigm as an Effort for Social Transformation in the Information Age
Authors: Lundeto Adri
Published: December 2021

This era of disruption is interpreted as how human life is heavily influenced by materialism, digitalism, and new capitalism to become a tremendous force. This study uses a cross-disciplinary strategy that integrates broad educational pedagogy and its implications in social life. This study uses two types of data sources: primary data and secondary data. From this study, it can be seen that social transformation is something that cannot be avoided in society. So that social values in society have changed. Previously, people expected everything to be modern with the help of technology. Now modern society feels sadness and loses the meaning of life, thus requiring a transformation to return to running a more humanistic community-based social system, especially in information and disruption.
KEBIJAKAN ALOKASI DANA DESA (ADD) DALAM RANGKA MENGOPTIMALKAN PEMBANGUNAN DESA
Authors: Restu Widyo Sasongko
Published: December 2021

Kebijakan Alokasi Dana Desa dalam kerangka pembangunan desa adalah meningkatkan kesejahteraan masyarakat desa dan kualitas hidup manusia serta penanggulangan kemiskinan. Salah satu ukuran dari peningkatan kesejahteraan masyarakat serta menurunnya angka kemiskinan suatu daerah adalah banyak sedikitnya jumlah keluarga sejahtera di daerah tersebut. Salah satu sumber pendapatan desa yang merupakan alokasi anggaran dari Anggaran Pendapatan dan Belanja Negara (APBN) adalah Dana Desa. Mengingat sumber Dana Desa adalah dari APBN, maka untuk mengoptimalkan penggunaannya pemerintah mempunyai kewenangan untuk menetapkan prioritas penggunaan Dana Desa untuk mendukung program pembangunan dan pemberdayaan masyarakat desa. Kebijakan Alokasi Dana Desa (ADD) merupakan dana perimbangan yang berasal dari pemerintah kabupaten/kota diserahkan pada pemerintah desa yang diharapkan menjadi penyangga utama pelaksanaan pemberdayaan masyarakat dan pembangunan desa sehingga dapat meningkatkan kesejahteraan masyarakat, melalui dana ini pemerintah desa bisa mengoptimalkan pembangunan yang mana tujuan utamanya untuk pemberdayaan serta menyejahterakan masyarakat yang ada di sebuah desa, artinya anggaran pemerintah yang diberikan kepada desa adalah untuk fasilitas pembangunan dan pemberdayaan desa sebagai salah satu lembaga yang andil dalam format kepemerintahan.
E-READINESS DALAM PENERAPAN E-PLANNING DI KABUPATEN MAMBERAMO TENGAH PROVINSI PAPUA
Authors: Nesty Epa  , Sampara Lukman  , Ella Wargadinata
Published: December 2021

Penelitian ini bertujuan untuk mengukur E-Readiness Kabupaten Mamberamo Tengah Dalam Penerapan E-Planning. Kabupaten Mamberamo Tengah secara geografis termasuk daerah yang memiliki keterbatasan akses, namun Di sisi lain harus melakukan inovasi yang tidak biasa untuk mengejar ketertinggalan dari daerah lainnya. Penelitian ini akan membahas eksisting kondisi serta syarat-syarat apa saja yang harus disiapkan oleh Kabupaten Mamberamo Tengah untuk menerapkan pelaksanaan perencanaan berbasis elektronik.

Penelitian ini menggunakan penelitian kualitatif. Metode yang digunakan dalam mengukur e-readiness yaitu metode e-readiness yang dikembangkan dari model hubungan variabel e-readiness menurut Musa (2010). Indikator-indikator yang diintegrasikan ke dalam kerangka pengukuran e-readiness dalam tool dipetakan ke dalam tiga faktor penting yang memengaruhi e-readiness yaitu faktor teknologi, faktor manusia dan faktor institusional khususnya di tingkat lokal (pemerintah daerah).

Hasil pengukuran e-readiness menunjukkan bahwa pemerintah Kabupaten Mamberamo Tengah belum siap dalam menerapkan e-planning baik diukur dari faktor teknologi, faktor manusia maupun faktor institusional, sehingga ini menjadi perhatian khusus bagi pemerintah daerah agar lebih serius dalam mempersiapkan pembangunan infrastruktur dan juga pemerintah daerah perlu membangun kerja sama antarpemerintah, pihak swasta dan juga masyarakat serta perlu adanya regulasi yang secara khusus berbicara tentang Sistem Informasi Perencanaan Daerah (SIPD) agar lebih baik ke depannya dan pelaksanaan e-planning dapat berjalan sesuai dengan peraturan yang berlaku secara efektif dan efisien.
An assessment of innovation in economic sectors of the Pridneprovsky Economic Region in Ukraine
Authors: Soldak Myroslava , Caputa Wiesława , Sozanskyy Lyubomyr
Published: December 2021

The article provides a comparative assessment of the innovativeness of Ukrainian and Polish manufacturing. The main types and kinds of innovation in different sectors of the Pridneprovsky Economic Region are identified and each kind of economic activity in the region is rated in terms of intensity and efficiency of development. It was found out that the most promising sector of the Pridneprovsky Economic Region was the engineering industry, where innovation is based on engineering developments and research. The authors provide economic justification for measures to increase intensity and efficiency, and hence the level of innovation of key economic activities of the region. What is required is an innovation-oriented ecosystem that provides conditions for research and development, the formation and development of networks that consolidate activities of research centers and science-intensive industrial production, training of professional staff; reliable protection of intellectual property, the development of industrial clusters; that facilitate access to global sources of technology, knowledge and highly qualified engineering and technical personnel.
Virtual look around: comparing presence, cybersickness and usability for virtual tours across different devices
Authors: Cheiran Jean Felipe Patikowski , Rodrigues Adriel , Pimenta Marcelo Soares
Published: December 2021

Virtual Reality has become readily available in the last few years through different devices, from desktop computers to head­-mounted displays (HMD). Also, virtual tours became popular with 360º panoramic photographs and video clips on online social media, so people could visit remote locations without being exposed to crowded transportation or long travels. Also, virtual tours demonstrate considerable potential as a form of escapism and even for remote teaching. Since we lack studies that evaluate the User Experience (UX) in virtual tours on different devices, this article aims to compare aspects of the User Experience (regarding sense of presence, cybersickness, and usability) in a virtual tour website developed in WebXR across different devices. To achieve our objective, we developed a virtual tour based on 360º pictures using WebXR API and React 360 framework and conducted an experiment with 41 undergraduate students using four different devices: a laptop computer, a smartphone, a Google Cardboard headset, and a Samsung Gear VR HMD. We evaluated users’ perceptions by adapting and translating the Suitability Evaluation Questionnaire (SEQ) and users’ performance by measuring the time to fulfill a set of tasks. The main findings from this study include that (i) the overall self-­reported experience using Google Cardboard is worse than using other devices, (ii) the users’ performance is quite similar between the platforms, (iii) there is evidence of unexpected cybersickness symptoms in tests with the smartphone, and (iv) the development of a plausible hypothesis concerning low usability having an effect upon the sense of presence. Additional contributions of our research are the adaptation, translation into Portuguese, psychometric analysis, and revised scoring procedures of the SEQ.
Text Mining for Cyberbullying Detection: a Brazilian Portuguese Evaluation
Authors: Eberhart Carolina , Ignaczak Luciano , Martins Márcio Garcia
Published: December 2021

Bullying and cyberbullying are words commonly seen in today's news. Although the scientific community has evaluated text mining techniques for cyberbullying detection, few studies have targeted Brazilian Portuguese datasets. Our study aims to assess the text mining application to detect cyberbullying messages written in Brazilian Portuguese. We gathered posts and comments from Reddit communities and extracted several text features. We then processed these features using Naïve Bayes and SVM classifiers to uncover cyberbullying activity. The outcomes of this experiment may not be used solo for cyberbullying detection; however, they can aid moderators in prioritizing content reviews and acting faster on real cyberbullying cases.
Relation extraction in structured and unstructured data: a comparative investigation on smartphone titles in the e-commerce domain
Authors: Barbirato João Gabriel Melo , Real Livy , Caseli Helena de Medeiros
Published: December 2021

As large amounts of unstructured data are generated on a regular basis, expressing or storing knowledge in a way that is useful remains a challenge. In this context, Relation Extraction (RE) is the task of automatically identifying relationships in unstructured textual data. Thus, we investigated the relation extraction on unstructured e-commerce data from the smartphone domain, using a BERT model fine-tuned for this task. We conducted two experiments to acknowledge how much relational information it is possible to extract from product sheets (structured data) and product titles (unstructured data), and a third experiment to compare both. Analysis shows that extracting relations within a title can retrieve correct relations that are not evident on the related sheet.
Annotation Difficulties in Natural Language Inference
Authors: Kalouli Aikaterini-Lida , Real Livy , Buis Annebeth , Palmer Martha , Paiva Valeria de
Published: December 2021

State-of-the-art models have obtained high accuracy on mainstream Natural Language Inference (NLI) datasets. However, recent research has suggested that the task is far from solved. Current models struggle to generalize and fail to consider the inherent human disagreements in tasks such as NLI. In this work, we conduct an experiment based on a small subset of the NLI corpora such as SNLI and SICK. It reveals that some inference cases are inherently harder to annotate than others, although good-quality guidelines can reduce this difficulty to some extent. We propose adding a Difficulty Score to NLI datasets, to capture the human difficulty level of agreement.
Palatalização na fala e na leitura de universitários sergipanos
Authors: Silva Lucas Santos , Freitag Raquel Meister Ko.
Published: December 2021

Apresentamos uma análise comparativa acerca da palatalização de /t/ e /d/ em duas amostras independentes, e com tamanho distinto, compostas por dados de fala (n = 8.850) e de leitura em voz alta (n = 831) de estudantes da Universidade Federal de Sergipe. Controlamos as variáveis sociais deslocamento e tempo no curso, e as variáveis linguísticas contexto anterior, contexto posterior, tonicidade e sonoridade, com o objetivo de identificar se os efeitos condicionantes da palatalização da fala atuam na leitura em voz alta. Os resultados sinalizam que, mesmo em amostras distintas, o comportamento dos fatores sociais e linguísticos apresentam estabilidade na mudança e propagação da palatalização na comunidade.
Descrição Preliminar do Corpus DANTEStocks: Diretrizes de Segmentação para Anotação segundo Universal Dependencies
Authors: Felippo Ariani Di , Postali Caroline , Ceregatto Gabriel , Gazana Laura S. , Silva Emanuel H. da , Roman Norton T. , Pardo Thiago A. S.
Published: December 2021

A anotação de textos informais segundo a Universal Dependencies requer dois processos de segmentação: delimitação da unidade relevante para a análise sintática e identificação das palavras sintáticas. Neste artigo, apresentam-se as idiossincrasias linguísticas do corpus DANTEStocks, composto por tweets do mercado financeiro, escritos em Português, e as estratégias gerais de segmentação automática. Assim, contribui-se para a descrição de aspectos linguísticos dos tweets e para o desenvolvimento de recursos e ferramentas de processamento automático desse subgênero de "user-generated content".
Criação e Anotação do corpus de resumos científicos de Ciências Sociais Aplicadas
Authors: Taniwaki Sabrina de Fátima Barbosa , Souza Jackson Wilke da Cruz
Published: December 2021

Com o crescente interesse e necessidade na criação de ferramentas (semi)automáticas que auxiliem o processo de letramento em gêneros textuais acadêmicos, apresentamos neste trabalho o corpus de resumos científicos em ciências sociais aplicadas. Nosso objetivo foi estudar, a nível sentencial, a estrutura retórica dos resumos das áreas de Administração Pública, Contabilidade e Economia, com base na tipologia proposta na literatura, por meio da ferramenta de anotação de corpus WebAnno. Tivemos como resultado, (i) a organização de um conjunto de 200 textos, (ii) o estudo preliminar da estrutura retórica das referidas áreas e (iii) a produção de um manual de anotação com diretrizes específicas sobre a identificação da estrutura retórica dos resumos científicos.
Utilizando Pistas Linguística para Detectar Conteúdo Enganoso em Português
Authors: Rodrigues Rodrigo F. , Freitas Larissa A. de
Published: December 2021

O maior acesso a celulares conectados à internet e a popularização das redes sociais levaram a um aumento significativo na geração e no compartilhamento de notícias falsas. Estudos disponíveis na literatura, baseados em pistas linguísticas, sugerem que os autores de conteúdo enganoso exibem comportamento verbal e não verbal diferente dos autores de conteúdo verdadeiro. Desta forma, neste artigo apresentamos a ferramenta LC-Tool, a qual extrai 29 pistas linguísticas de textos. Ainda, testamos a ferramenta em três corpus sobre conteúdo enganoso disponíveis na Internet. Por fim, percebemos que algumas pistas linguísticas podem ser extensíveis para o idioma português (por exemplo: média do número de verbos e média de pausalidade) e que em outras pistas linguísticas precisam ser validadas, pois são afetadas pelo contexto e domínio das mensagens.
Integrative Psychosenpsychotherapie
Authors: Schmidt-Hoffmann Friederike
Published: December 2021

Menschen mit Psychoseerfahrungen werden vorwiegend stationär und pharmakologisch behandelt. Diese gängige Behandlung soll um Psychotherapie ergänzt werden: Die Autorin ermutigt psychotherapeutisch Tätige, ihr Wissen einzusetzen und stellt theoretisch fundierte und versorgungsnahe Perspektiven auf psychotische Störungen vor.

Menschen mit Psychose-Erfahrungen werden im therapeutischen Alltag oft anders behandelt als Menschen mit anderen Störungsbildern – dabei können »allgemeine« Ansätze der Psychotherapie auch bei Psychosen angewandt werden. Die Autorin ermutigt psychotherapeutisch Tätige, ihr Wissen auch hier einzusetzen, und stellt theoretisch fundierte und versorgungsnahe Perspektiven auf psychotische Störungen vor.

Schulenübergreifend führt das Buch in das psychosespezifische Arbeiten ein, weist auf die Besonderheiten von Psychosebehandlungen hin und fördert anhand vieler Fallbeispiele den Mut für die Therapie mit Psychose-Erfahrenen.

Das Buch wirbt für einen biografisch verstehenden Zugang und zeigt auf, wie schematherapeutisch orientiertes Arbeiten im Rahmen eines integrativen, emotions- und bedürfnisorientierten Ansatzes Genesungsprozesse fördern kann. Es macht vorhandene theoretische Kenntnisse für die praktische Arbeit nutzbar und vermittelt eine sensible therapeutische Haltung, die auf Recovery, Selbstwirksamkeit und Empowerment ausgerichtet ist.
SMARCA4/BRG1-Deficient Sinonasal Carcinoma
Authors: Kakkar Aanchal , Ashraf Subiyathul Farah , Rathor Amber , Adhya Amit Kumar , Mani Suresh , Sikka Kapil , Jain Deepali
Published: December 2021

Context.—

Molecular analysis of poorly differentiated/undifferentiated sinonasal neoplasms has resulted in identification of a growing number of genetically defined tumors. SMARCA4-deficient sinonasal carcinoma is one such recently described entity that emerged from within sinonasal undifferentiated carcinoma (SNUC), neuroendocrine carcinoma (NEC), and teratocarcinosarcoma (TCS).

Objective.—

To identify SMARCA4-deficient sinonasal carcinomas from a large institutional cohort of poorly differentiated/undifferentiated carcinomas and evaluate their clinicopathologic features.

Design.—

SMARCA4/BRG1 immunohistochemistry was performed on all tumors diagnosed as SNUC, poorly differentiated carcinoma, NEC, and TCS during a 12-year period. SMARCA2/BRM and INSM1 immunostaining was performed in SMARCA4-deficient cases.

Results.—

Twelve SMARCA4-deficient sinonasal carcinomas were identified among 299 cases. Morphologically, 5 cases were large cell NEC, 2 cases were small cell NEC, and 5 were TCS. SMARCA4 loss was diffuse and complete in 10 cases, while 2 cases showed focal retention. Most cases showed diffuse cytokeratin staining accompanied by weak, usually focal staining for chromogranin and synaptophysin. INSM-1 showed negativity in most cases. All cases showed retained SMARCA2 expression. IDH1/2 mutation was absent in all cases analyzed. Four of 7 patients died of disease, and aggressive multimodality treatment provided better outcome.

Conclusions.—

SMARCA4-deficient sinonasal carcinomas are morphologically akin to sinonasal poorly differentiated NECs and TCS, display cytokeratin positivity and only focal staining for neuroendocrine markers, and have aggressive biological behavior. Inclusion of SMARCA4 in the immunohistochemical panel for diagnostic workup of all sinonasal NEC and TCS phenotypes will facilitate their early recognition. Comprehensive germline and somatic mutational analyses of these tumors are necessary for further insights into their molecular pathogenesis.
Letter from the Editors
Authors: Taylor Nik , Nolan Stuart , Hoedt Madelon
Published: December 2021

n/a
Military cliques in the Serbian strategic culture of the 20th century
Authors: Blagojević Veljko , Petrović Dejan
Published: December 2021

Throughout the entire 20th century, the Serbian strategic culture was "torn" by various discontinuities, from the state system, through foreign policy and ideological, to strategic and doctrinal orientation, and it can be said that discontinuity is almost its only constant. Nevertheless, the existence of military cliques can be considered to be one of the constants of the Serbian strategic culture. They followed the Serbian Army and influenced the political life of the Kingdom of Serbia. The dynastic coup of May 1903 can be taken as an example of their actions. After that, younger conspirators established the so-called Black Hand, whose leader was Colonel Apis, who was shot after the Thessaloniki process in 1917. The interwar period was marked by the action of the so-called White Hand, under the leadership of General Petar Živković, which was active until the assassination of King Alexander Karađorđević in Marseilles in 1934. The Second Yugoslavia even had a formalized "military clique" represented in the League of Communists, which was an integral part of the League of Communists of Yugoslavia at federal level, together with the republican leagues. Thus, the influence of the party on the military organization was secured, and the influence of the army in the society was also "secured" by its representation in the party forum at federal level. Consequently, the Serbian political elite welcomed the dissolution of the SFRY with perhaps the only constant in its strategic culture, and that is the reliance on the military in resolving political crises, which can be vividly presented by the statement of Slobodan Milosević: "We do not know how to work, but we know how to fight".
Fremskridtets lyd?
Authors: Ingemann Parby Jakob
Published: December 2021

Artiklen undersøger håndteringen af støj under den københavnske industrialisering i anden halvdel af 1800-tallet i et lydhistorisk perspektiv. Med udgangspunkt i den internationale forskning i periodens såkaldte lydrevolution undersøges det, hvordan industrialiseringen konkret påvirkede og omdefinerede det københavnske byrum på henholdsvis gadeplan, på arbejdspladsen og i nabolaget, samt hvordan oplevelsen af støj og strategier for dens inddæmning og håndtering udviklede sig i perioden under indflydelse af nye lyttepraksisser og en øget opmærksomhed på lyd og larm i flere samfundslag.
The impact of conceptual structures on transaction and enterprise architecture practices
Authors:   , Fallon Richard Lindsay
Published: December 2021

This research hypothesises is Conceptual Structures using the Resource Event Agent (REA) ontology adds value when defining a Transaction Oriented Architecture (TOA) for Enterprise Systems. Enterprise Systems drive global economic growth through well-designed implementations that provide organisations with multiple benefits, including streamlined business processes, increased efficiencies, improved productivity and decreased costs. Conversely, poorly implemented Enterprise Systems can lead to poor operating results. Most Enterprise Systems still use traditional methods of storing economic data mirroring the double-entry bookkeeping system, which can cause several problems, including data loss and repetition. Enterprise Systems must capture transaction data in a format available to multiple business processes to fulfil their goals. This thesis provides an overview of the currently available frameworks for Enterprise Architecture design. It details the problems that are observed and experienced during the completion of real-world Enterprise System development projects. The basis of the Transaction Concept is then presented as the general solution, leading to a TOA for Enterprise Systems. The Transaction Pyramid describes TOA through three layers of transactions: Enterprise, Business, and Database. The Design Science Research Methodology (DSRM) is used as the primary research methodology to provide a framework to this research. Together with the secondary research method of Action Research to provide a more granular basis for DSRM Step 3 : "Design and development", which required multiple minor iterations of the cyclical process of Action Research to produce the required artefacts. The case study approach is used also as a secondary research method for empirical inquiry and investigation required for DSRM step 4: "Demonstration". A Knowledge Management System is defined to validate TOA, and artefacts are implemented for an Automated REA (AREA) based on Protégé Frames to underpin TOA as a Proof of Concept. AREA provides a fully- edged, TOA design tool for Enterprise Architecture using the REA ontology. AREA's Knowledge Repository uses Conceptual Structures through a) the ISO Common Logic standard's Conceptual Graph Interchange Format (CGIF) to store and transmit the TOA using an REA ontology, and b) Formal Concept Analysis (FCA) for validation. AREA is then demonstrated and evaluated using two industrial case studies as exemplars. These Findings support the research's hypothesis and its contribution to knowledge.
Kustīgās slodzes dinamiskās iedarbes uz autoceļu tiltiem eksperimentāla izpēte un novērtējums
Authors: Paeglīte Ilze
Published: December 2021

Using data obtained from the dynamic load testing of bridges a method was developed to evaluate level of the dynamic performance without performing a dynamic load test. In this method a dynamic index of the bridge is calculated. Dynamic index allows to evaluate the dynamic performance level of existing and new structures taking into account such bridge parameters as span length / height ratio, natural frequency, vibration damping coefficient, relative deflection and international roughness index IRI. Dynamic index method can be used by bridge owners and maintainers to determine the dynamic potential of a particular bridge. The maximum allowable values of the dynamic amplification factor for standard prestressed concrete beam bridges were determined. These values were calculated for maximum allowed traffic load in Latvia. The obtained results can be used for the safety assessment of existing and reconstructed reinforced concrete beam bridges.
Brain Gym Effectively Reduces Anxiety in School-and Preschool-Aged Children in Hospitals
Authors: Arbianingsih Arbianingsih , Huriati Huriati , Hidayah Nur , Musnayni Syarifah , Afiifah Nuravia , Amal A. Adriana
Published: December 2021

Hospitalization-induced anxiety in children can impede healing and lengthen hospitalization. As such, appropriate interventions are needed to reduce their anxiety during hospitalization. For example, brain exercise has been shown to reduce anxiety in children in diverse settings and developmental stages. This study was performed to compare the effect of brain exercise on anxiety in hospitalized school-and preschool-aged children. A pre-experimental pre/ posttest design was used, and 32 children were selected by consecutive sampling. Brain gym was given twice a day for 2 consecutive days. Data were collected from school-aged children by using a modified Zung Sel-Rating Anxiety Scale and Tailor Manifest Anxiety Scale and from preschoolers by utilizing a modified Hamilton Anxiety Rating Scale observation sheet. Wilcoxon test results showed that brain gyms were effective in reducing anxiety in school-aged children (p = 0.016) and preschoolers (p = 0.006). Movements during brain exercises could activate the neocortex and parasympathetic nerves that can ease psychic and physical tension. Therefore, brain gym can be an effective intervention to decrease anxiety in preschoolers and school-aged children. Abstrak Brain Gym Efektif Menurunkan Kecemasan Pada Anak Usia Sekolah dan Pra Sekolah di Rumah Sakit. Kecemasan akibat rawat inap pada anak dapat menghambat penyembuhan dan memperpanjang rawat inap. Dengan demikian, intervensi yang tepat diperlukan untuk mengurangi kecemasan mereka selama dirawat di rumah sakit. Misalnya, latihan otak telah terbukti mengurangi kecemasan pada anak-anak dalam berbagai pengaturan dan tahap perkembangan. Penelitian bertujuan untuk membandingkan pengaruh senam otak terhadap kecemasan pada anak usia sekolah dan prasekolah yang dirawat di rumah sakit. Penelitian menggunakan desain pre-eksperimen pre/posttest, dan 32 anak dipilih dengan sampel konsekutif. Senam otak diberikan dua kali sehari selama dua hari berturut-turut. Data yang dikumpulkan dari anak-anak usia sekolah menggunakan modifikasi Zung Sel-Rating Anxiety Scale dan Tailor Manifest Anxiety Scale, sedangkan data anak-anak prasekolah menggunakan lembar observasi modifikasi Hamilton Anxiety Rating Scale. Hasil uji Wilcoxon menunjukkan bahwa senam otak efektif menurunkan kecemasan pada anak usia sekolah (p = 0,016) dan anak prasekolah (p = 0,006). Gerakan pada saat senam otak dapat mengaktifkan neokorteks dan saraf parasimpatis yang dapat meredakan ketegangan psikis dan fisik. Oleh karena itu, senam otak dapat menjadi intervensi yang efektif untuk menurunkan kecemasan pada anak prasekolah dan usia sekolah. Kata Kunci: kecemasan, prasekolah, senam otak, usia sekolah
Chronic Liver Disease Lowering Physical and Mental Health Dimensions
Authors: Siburian Apriliani , Chang Ching Fen
Published: December 2021

The most prevalent diseases within the world related to major illness and mortality are chronic liver diseases. The developing pervasiveness of chronic liver disease has resulted in increased interest in health-related quality of life, which incorporates the physical well-being of a patient and his emotional and social well-being. This study aimed to define the quality of life of patients with chronic liver disease. This study used the Quality-of-Life Short Form 36 Indonesian version to examine 102 patients with chronic liver disease from two hospitals with a descriptive design. The quality of life of the patients was comparatively low (M ± SD: physical, 42.4 ± 18.33; mental, 48.44 ± 17.19). On both the physical and mental health dimensions of quality of life, the patients in this study scored less than 50 on a scale of 0 to 100, with low scores indicating the low quality of life both physically and mentally. Improving quality of life necessitates a multidisciplinary strategy that combines physical and mental health screening and management. Surrounding support will encourage adaptive coping mechanisms to manage the illness for improving quality of life. AbstrakPenyakit Hati Kronis Menurunkan Dimensi Kesehatan Fisik dan Mental. Penyakit yang paling umum di dunia yang berhubungan dengan penyakit utama dan kematian adalah penyakit hati kronis. Penyebaran penyakit hati kronis yang berkembang telah menghasilkan peningkatan minat pada kualitas hidup yang berhubungan dengan kesehatan, yang mencakup kesejahteraan fisik pasien dan kesejahteraan emosional dan sosialnya. Tujuan dari penelitian ini adalah untuk menjabarkan kualitas hidup pasien penyakit hati kronis. Penelitian ini menggunakan Quality-of-Life Short Form 36 versi Bahasa Indonesia untuk mengumpulkan data dari 102 pasien dari dua rumah sakit melalui desain deskriptif. Penelitian ini menunjukkan bahwa kualitas hidup pasien relatif rendah (M ± SD: fisik, 42,4 ± 18,33; mental, 48,44 ± 17,19). Pada kedua dimensi kualitas hidup yaitu kesehatan fisik dan mental, pasien dalam penelitian ini mendapat nilai kurang dari 50 pada skala 0 hingga 100, dengan nilai rendah menunjukkan kualitas hidup rendah baik fisik maupun mental. Peningkatkan kualitas hidup pasien memerlukan strategi multidisiplin yang menggabungkan skrining dan manajemen kesehatan fisik dan mental. Dukungan lingkungan akan mendorong mekanisme koping yang adaptif untuk mengelola penyakit dalam meningkatkan kualitas hidup.Kata Kunci: Indonesia, kualitas hidup, penyakit hati kronis, sirosis
Post-Stroke Quality of Life Perceived by Patients and Caregivers
Authors: Medea Gitalia Putri , Nurachmah Elly , Adam Muhamad
Published: December 2021

The quality of life (QOL) of post-stroke patients can be assessed from the reports of patients themselves obtained through a structured interview or a questionnaire. However, some individuals are unable to comprehensively describe their QOL because of language disorders, cognitive effects caused by stroke, or pre-existing conditions. This study aims to identify differences in post-stroke QOL perception between patients and caregivers. A cross-sectional design involving 115 stroke patients and 115 caregivers was adopted, and Mann–Whitney test was used for statistical analysis. Results showed no significant difference in QOL perception (p = 0.166; α < 0.05), particularly in the physical (p = 0.278; α < 0.05), psychological (p = 0.068; α < 0.05), social relationship (p = 0.976; α < 0.05), and environmental (p = 0.157; α < 0.05) domains between patients and caregivers. Therefore, information from caregivers can be used to assess QOL when patients are incapable of reporting their condition. AbstrakKualitas Hidup Pasca Stroke yang Dipersepsikan oleh Pasien dan Caregiver. Kualitas hidup pasien pasca stroke dapat diketahui berdasarkan laporan dari pasien stroke dengan wawancara terstruktur atau dengan pengisian kuesioner. Namun, beberapa dari pasien stroke tidak dapat menggambarkan kualitas hidup mereka karena adanya gangguan bahasa dan efek kognitif lainnya akibat stroke atau kondisi yang sudah ada sebelumnya. Penelitian ini bertujuan mengidentifikasi perbedaan persepsi kualitas hidup antara perspektif pasien pasca stroke dan  caregiver. Penelitian ini menggunakan desain cross sectional yang melibatkan 115 pasien dan 115 caregiver dengan menggunakan analisis statistik Mann Whitney. Hasil analisis menunjukkan tidak terdapat perbedaan secara signifikan antara persepsi kualitas hidup dari pasien dan caregiver (p = 0,166 ; α < 0,05), khususnya pada domain fisik (p = 0,278; α < 0,05), psikologis (p = 0,068; α < 0,05), hubungan sosial (p = 0,976; α < 0,05), dan lingkungan (p = 0.157; α < 0,05) dari kualitas hidup yang dipersepsikan oleh pasien dan yang dipersepsikan oleh caregiver. Informasi dari caregiver dapat digunakan saat pasien tidak dapat memberikan informasi terkait kualitas hidupnya.Kata Kunci: caregiver, kualitas hidup, persepsi, stroke
Association of lipid-lowering drugs with COVID-19 outcomes from a Mendelian randomization study
Authors: Huang Wuqing , Xiao Jun , Ji Jianguang , Chen Liangwan
Published: December 2021

Background:

Lipid metabolism plays an important role in viral infections. We aimed to assess the causal effect of lipid-lowering drugs (HMGCR inhibitiors, PCSK9 inhibitiors, and NPC1L1 inhibitior) on COVID-19 outcomes using two-sample Mendelian randomization (MR) study.

Methods:

We used two kinds of genetic instruments to proxy the exposure of lipid-lowering drugs, including expression quantitative trait loci of drugs target genes, and genetic variants within or nearby drugs target genes associated with low-density lipoprotein (LDL cholesterol from genome-wide association study). Summary-data-based MR (SMR) and inverse-variance-weighted MR (IVW-MR) were used to calculate the effect estimates.

Results:

SMR analysis found that a higher expression of HMGCR was associated with a higher risk of COVID-19 hospitalization (odds ratio [OR] = 1.38, 95% confidence interval [CI] = 1.06–1.81). Similarly, IVW-MR analysis observed a positive association between HMGCR-mediated LDL cholesterol and COVID-19 hospitalization (OR = 1.32, 95% CI = 1.00–1.74). No consistent evidence from both analyses was found for other associations.

Conclusions:

This two-sample MR study suggested a potential causal relationship between HMGCR inhibition and the reduced risk of COVID-19 hospitalization.

Funding:

Start-up Fund for high-level talents of Fujian Medical University.
Endogenous protein tagging in medaka using a simplified CRISPR/Cas9 knock-in approach
Authors: Seleit Ali , Aulehla Alexander , Paix Alexandre
Published: December 2021

The CRISPR/Cas9 system has been used to generate fluorescently labelled fusion proteins by homology-directed repair in a variety of species. Despite its revolutionary success, there remains an urgent need for increased simplicity and efficiency of genome editing in research organisms. Here, we establish a simplified, highly efficient, and precise strategy for CRISPR/Cas9-mediated endogenous protein tagging in medaka (Oryzias latipes). We use a cloning-free approach that relies on PCR-amplified donor fragments containing the fluorescent reporter sequences flanked by short homology arms (30–40 bp), a synthetic single-guide RNA and Cas9 mRNA. We generate eight novel knock-in lines with high efficiency of F0 targeting and germline transmission. Whole genome sequencing results reveal single-copy integration events only at the targeted loci. We provide an initial characterization of these fusion protein lines, significantly expanding the repertoire of genetic tools available in medaka. In particular, we show that the mScarlet-pcna line has the potential to serve as an organismal-wide label for proliferative zones and an endogenous cell cycle reporter.
The phylogenetic affinities and morphological peculiarities of the bird-like dinosaurBorogovia gracilicrusfrom the Upper Cretaceous of Mongolia
Authors: Cau Andrea , Madzia Daniel
Published: December 2021

Borogovia gracilicrusis a small-bodied theropod dinosaur from the Maastrichtian (Upper Cretaceous) Nemegt Formation of southern Mongolia. The taxon is based on a single fragmentary specimen preserving only the distal part of the hindlimbs. The morphology ofBorogoviashows a peculiar combination of features, some of which are traditionally considered troodontid synapomorphies and others which are unusual for Troodontidae but are shared with other maniraptoran clades. In particular, the second toe ofB. gracilicrusdiffers from other troodontids in lacking some of the features which contribute to the specialized ‘sickle-clawed’ second toe, here termed the ‘falciphoran condition’, shared with dromaeosaurids and some other paravians, such as the strongly compressed and falciform ungual. Phylogeny reconstructions intended to explore the affinities ofBorogoviaconsistently support its referral within a subclade of troodontids including all Late Cretaceous taxa. The placement ofBorogoviais not significantly affected by its unusual combinations of hindlimb features or by the homoplasy of the elements forming the falciphoran condition.Borogoviais supported as a valid taxon and is distinct from the other Nemegt troodontids,TochisaurusandZanabazar. The lack of a falciform ungual, and the distinctive morphology of the second toe inB. gracilicrusare interpreted as a derived specialization among Troodontidae and not as retention of the plesiomorphic condition of non-paravian theropods.
Informação prospectiva: estratégia de ação no comércio informal do vestuário
Authors: Silva Mayara Santos , De Vasconcelos César Ricardo Maia
Published: December 2021

A presente pesquisa dedicou-se à exploração de novos conhecimentos sobre a temática “informação prospectiva: estratégia de ação no comércio informal do vestuário feminino”. O trabalho foi realizado na cidade de Picuí/PB e região e se propôs a entender a percepção dos clientes atuais e potenciais com relação a essa estratégia de desenvolvimento. O objetivo de estudo é conhecer a influência que a informação prospectiva exerce sobre o mercado informal do vestuário feminino. Foi realizada revisão da literatura, tanto nacional quanto internacional. Este estudo representa um paradigma construtivista e de investigação qualitativa, possuindo um caráter descritivo e exploratório e utilizando-se de entrevistas semiestruturadas para a coleta de dados, a qual totalizou trinta entrevistados. As entrevistas ocorreram por meio de gravador de áudio e contaram com posterior transcrição para tratamento e análise das categorias temáticas, sugeridas por Bardin (2011), com a ajuda do software “NVivo 11”. Os resultados foram relacionados em quatro categorias: Informação prospectiva, Vestuário feminino, Comércio informal e Inteligência competitiva. Há também seis subcategorias: Moda e consumo, “Boca a boca” e redes sociais, Informação, Grau de satisfação, Processo de informação e Tomada de decisões. A análise dos resultados obtidos a partir do instrumento de pesquisa apresentou que os entrevistados consideram a informação prospectiva matéria-prima da Inteligência Competitiva, como estratégia de ação na tomada de decisão. Conclui-se que, na percepção dos respondentes, a informação prospectiva é considerada uma estratégia de ação no mercado informal de vestuário feminino. Por último, encontram-se limitações e sugestões futuras para essa temática.
Uma abordagem à satisfação dos responsáveis pelos alojamentos turísticos à alocação de recursos dos municípios portugueses
Authors: Soares Rodrigo Pedro , Sarmento Manuela
Published: December 2021

Gerir é uma tarefa sempre difícil uma vez que, existem demasiadas variáveis envolvidas e que se torna ainda mais complicada quando as perspectivas futuras são incertas. Efetivamente, a partir do final de 2019, devido à propagação do SARS-CoV2 o turismo tornou-se altamente vulnerável e os responsáveis pelos alojamentos turísticos tiveram quebras de receitas bastante avultadas. O objetivo deste artigo é analisar, de que forma os responsáveis das empresas de alojamentos turísticos percepcionam, em termos de satisfação, a alocação de recursos que é feita pelos municípios. Para tal recorreu-se a metodologias estatísticas tais como: descritivas, análise componentes principais, regressão linear múltipla e regressão logística ordinal. As conclusões remetem para a importância da divulgação feita pelos municípios na satisfação global dos responsáveis pelo alojamentos turísticos. Contudo, o apoio ao turista e à realização de eventos também se mostrou relevante em termos de alocação de recursos por parte dos municípios.