bluuebunny/crossref_metadata_2025 huggingface dataset:
Primary non-Hodgkin's lymphoma of the temporal bone
Authors:   Nicolae Testemitanu State University of Medicine and Pharmacy, Republic of Moldova, Danilov Lucian , Ababii Polina ,   Children's Clinical Hospital "Emilian Cotaga", Republic of Moldova, Didencu Alexandru ,   Children's Clinical Hospital "Emilian Cotaga", Republic of Moldova, Smetanca Vladimir ,   Children's Clinical Hospital "Emilian Cotaga", Republic of Moldova, Fortuna Valeriu ,   Children's Clinical Hospital "Emilian Cotaga", Republic of Moldova, Railean Silvia ,   Nicolae Testemitanu State University of Medicine and Pharmacy, Republic of Moldova, Maniuc Mihail ,   Nicolae Testemitanu State University of Medicine and Pharmacy, Republic of Moldova, Gavriluta Vasile ,   Children's Clinical Hospital "Emilian Cotaga", Republic of Moldova, Botnaru Daniela ,   Nicolae Testemitanu State University of Medicine and Pharmacy, Republic of Moldova
Published: July 2021

We present a 6-year-old child, hospitalized in MSPI Institute of Mother and Child, Emilian Coţaga Clinic, Pediatric Otorhinolaryngology Department, Chisinau, Republic of Moldova, with primary non-Hodgkin’s lymphoma (NHL) of the temporal bone, with paresis of facial nerve.
Central giant cell granuloma in the mandibula: clinical, radiological and histopathological study in 2 clinical cases
Authors:   Nicolae Testemitanu State University of Medicine and Pharmacy, Republic of Moldova, Tibirna Gheorghe , Railean Silvia ,   Nicolae Testemitanu State University of Medicine and Pharmacy, Republic of Moldova, Porosencov Egor ,   Nicolae Testemitanu State University of Medicine and Pharmacy, Republic of Moldova, Porosencova Tatiana ,   Nicolae Testemitanu State University of Medicine and Pharmacy, Republic of Moldova, Lupan Roman ,   Nicolae Testemitanu State University of Medicine and Pharmacy, Republic of Moldova
Published: July 2021

Central giant cell granuloma (CGCG) is a benign and proliferative lesion of the jaw, with an unknown etiology. It is widely considered to be a neoplastic lesion. The current etiology of GCGC is still unclear, although local inflammation, bleeding, and trauma have been suggested. The biological behavior of CGCG of the jaw varies from resting to aggressive with destructive expansion. The incidence in the general population is very low, and patients are generally under 30 years of age females. In this study, we report two cases of GCGC in 8-year-old and 13 year old girls treated surgically.
Maxillary sinusitis of tumoral origin
Authors:   Nicolae Testemitanu State University of Medicine and Pharmacy, Republic of Moldova, Hitu Dumitru , Chele Nicolae ,   Nicolae Testemitanu State University of Medicine and Pharmacy, Republic of Moldova, Scerbatiuc Dumitru ,   Nicolae Testemitanu State University of Medicine and Pharmacy, Republic of Moldova, Cabac Vasile ,   Nicolae Testemitanu State University of Medicine and Pharmacy, Republic of Moldova, Badarau Lilia ,   Nicolae Testemitanu State University of Medicine and Pharmacy, Republic of Moldova, Mogildea Maria ,   Nicolae Testemitanu State University of Medicine and Pharmacy, Republic of Moldova
Published: July 2021

We present a retrospective study, which was performed on a batch of 177 patients diagnosed with maxillary sinusitis, selected from the total number of patients with OMF disorders during 2017-2018. The patients were examined and treated at the Department of Emergency Medicine of the Institute of Emergency Medicine, Chisinau. The article contains statistical data on maxillary sinusitis and the breakdown by age, sex, profession, etiology, addressability, place of life, hospitalization, causal tooth and treatment methods. Results: Out of the total number of 3227 patients with OMF, maxillary sinusitis (5.48%) was established for 177 patients. The majority of the patients 52.54% are from Chisinau. The most affected are the patients aged 31-40 years, constituting 26.56%, the majority being male persons 63.27%. Admission by itself to the medical institution prevailed for 74.01% of the cases by itself, and the medical insurance was presented for 77.97%. Hospitalization of patients ranged from 1-5 days for 55.35%. The frequency of teeth involved in the inflammatory processes of the sinus was 41.78% cases, of which 1st molar prevails with 23.16%, thus being an etiological factor. As a surgical treatment of maxillary sinusitis in the section of oro-maxillo-facial surgery, radical cure is used for 58.75% cases.
References to dental hypoplasia
Authors:   Nicolae Testemitanu State University of Medicine and Pharmacy, Republic of Moldova, Turcan Iuliana , Railean Silvia ,   Nicolae Testemitanu State University of Medicine and Pharmacy, Republic of Moldova, Avornic Lucia ,   Nicolae Testemitanu State University of Medicine and Pharmacy, Republic of Moldova, Ciumeico Igor ,   Nicolae Testemitanu State University of Medicine and Pharmacy, Republic of Moldova
Published: July 2021

Hypoplasia is assigned to a primary defect of the ameloblast that transitory secretes an abnormal substance incapable of normal mineralization. Once the action of the dystrophic factor slows down, the ameloblast resumes normal function. The growth lines, Retzius striations, of the hypoplasia area are more pronounced, and the width of this area corresponds to the duration of action of the dystrophic factor.
REASONS FOR CHANGE OF GENERAL PRACTITIONER - STUDY AMONG PATIENTS
Authors:   Department of Therapeutic Care, Faculty of Health Care, Medical University - Pleven, Bulgaria., Vasileva Biserka I. , Karcheva Milena D. ,   Department of Epidemiology, Faculty of Public Health, Medical University - Pleven, Bulgaria.
Published: July 2021

The health reform carried out in our country has resulted in a number of both positive and undesirable results in outpatient medical care, which requires an increase in the level of public health in the country. The introduction of free choice of GPs in our country made it possible for his patients to change freely. The purpose of this study is to analyze the patient's motives for changing P. Material/methods: A survey was conducted among respondents in the period 1-30 September 2018 in the Pleven region. Patients visited their GPs during the study period. A direct individual anonymous survey was conducted containing 35 questions, of which 29 closed questions, 4 semi-open and 2 open-ended questions. The results were processed through Microsoft Office Excel 2007. Results: The analysis of a number of authors, as well as our own empirical research, show the existence of a number of motives for changing the choice of patients for a personal physician. The patient's prior knowledge of the qualities and competencies of the chosen physician is very low. This choice of patients is most often spontaneous, random and not sufficiently substantiated with specific information. In any case, this reduces the effectiveness of the free choice of doctor. Conclusions: It is necessary to improve the organization of admission of patients by GPs.
Methamphetamine dependence and domestic violence among police detainees
Authors: Morgan Anthony , Gannoni Alexandra
Published: July 2021

This study explores the relationship between methamphetamine dependence and domestic violence among male police detainees interviewed as part of the Drug Use Monitoring in Australia program. Detainees who were dependent on methamphetamine reported high rates of domestic violence. They were significantly more likely to have been violent towards an intimate partner in the previous 12 months than detainees who used methamphetamine but were not dependent. Similar patterns were observed for detainees who reported cannabis dependence. Attitudes minimising the impact of violence were also associated with an increased likelihood of domestic violence. The results illustrate the importance of integrated responses that address the co-occurrence of substance use disorders and domestic violence, and the underlying risk factors for both harmful behaviours.
Manufacturing performance system for SMEs: A prioritization of KPIs with fuzzy analytic hierarchy process
Authors:   Department of Sustainable Corporate Development, Technical University of Berlin, Berlin, Germany, Nguyen Hien N. , Huynh Nhan H. ,   Faculty of Airport, Vietnam Aviation Academy, Ho Chi Minh City, Vietnam 3Faculty of Mechanical Engineering, Bach Khoa University, Ho Chi Minh City, Vietnam, Nguyen Cuong T. ,   Faculty of Mechanical Engineering, Bach Khoa University, Ho Chi Minh City, Vietnam
Published: July 2021

In today’s increasing competitive global market, large and successful manufacturing enterprises have implemented the system of key performance indicators (KPIs) which drives the performance toward the business objectives; however, this is not the case for small-medium sized enterprises (SMEs) which have been increasingly important for any national economy, especially in manufacturing sector. Although the KPIs can ideally be constructed in accordance with the concept of SMART (Specific, Measureable, Attainable, Realistic, Time-related) or balanced scorecard, but SMEs that are lack of limited resources and expertise could rarely afford to build such systems with the appropriate definition and measurement of KPIs. Therefore, the paper aimed to provide systematically the system of KPIs adaptable to SMEs, to prioritize the importance of each proposed KPI with the application of a fuzzy analytic hierarchy process (FAHP), and to instruct the comprehensive deployment of the SMEs’ manufacturing performance system.
In This Issue: Open call papers, and more papers and commentaries on the impact of COVID-19 on the food system
Authors: Hilchey Duncan
Published: July 2021

Have we finally turned the corner on COVID-19? Just maybe. The world is still reeling from the pandemic, and the delta variant is taking its toll presently, but the winds of change do seem to be shifting in our favor. After publishing more than a year and a half’s worth of research-based papers and commentaries on COVID-19 and its impact on the food system, we are taking a kind of odd pleasure in finally publishing content on a broader range of issues. Food systems work is (or should be) a veritable beehive of activity on all fronts, at all levels, at all times: racial equity, family farm resilience, climate change, building out our food security infrastructure, and so on require constant simul­taneous attention, each of these key issues being a piece of an interlocking resilience puzzle. . . .
THERAPEUTIC ADHERENCE IN PATIENTS WITH CHRONIC DISEASES OF THE CLUB OF OLDER ADULTS OF A HEALTH CENTER, ECUADOR
Authors: Albuja Landi Ana Karina , Gallegos Janneth , Vargas Cali Paola , Arguello Hernández Paola
Published: July 2021

One of the traditional fresh cheeses in Ecuador is the artisanal leafcheese, a kind of stretched-curd cheese. The artisanal product is wrapped in achira leaves (Canna indica), while the industrial leafcheese is packed at vacuum in high density polyethylene bags. In this study the microbiological quality of both products was compared. The hygienic-sanitary microbial indicators and lactic acid bacteria (LAB) were quantified. The LAB isolated were characterized phenotypically. The samples were obtained from artisanal cheese-making and industrial located in Latacunga city province Cotopaxi.
The total aerobic mesophilic count was made based on national regulations (NTE INEN 1529 5); total coliforms, Escherichia coli and Staphylococcus aureus was evaluated using petrifilm methods (AOAC 991.14 – AOAC 2003.07) and to LAB was used PRT-712.02-047. The results show high quantities of total coliforms, E. coli and S. aureus in both products, these data exceed the limits of acceptability established in Ecuadorian regulations, this evidence poor hygienic quality of the processes or incorrect controls of milk as raw material. The lactic acid bacteria count showed statistically significant differences, the industrial cheeses had a reduction of 18,15% of Lactobacillus and 14,27% of Lactococcus compared with artisanal cheeses. A total of 32 strains of lactic acid bacteria were isolated, these showed similar phenotypic characteristics, but these had a different response at the level of pH (4,4;9,4) and NaCl (6,5%). The sensory evaluation will be an important complement in this type of study.
PHARMACY AND MEDICINAL PLANTS IN THE LITERATURE: CASE OF GARCÍA MÁRQUEZ
Authors: González Minero Francisco José , Bravo Díaz Luis
Published: July 2021

It is a bibliographic work that aims to obtain a “Pharmaceutical Look” at the work of García Márquez. It relates medicinal or associated plants, some medicinal and pharmaceutical aspects, with literary works that appear in a representative sample of the author’s novels, including One Hundred Years of Solitude and Love in the Times of Cholera.
These novels take place in imaginary or real places in Colombia in the 19th century and the first half of the 20th. Plant remedies and to a lesser extent chemical and animal remedies have been found. For each of them, observations and interpretations medical, social and histórical, have been made that value the pharmacy and medicinal plants, which the author has used as resources to build the novels, regardless of whether they have a scientific basis or not. For this they are accompanied by textual literary texts. In conclusion, we highlight the masterful way in which García uses these resources and we recommend their reading or re-reading, also taking into account that at the same time it can be done from a pharmaceutical point of view.
HEALTHY AND SUSTAINABLE FOOD HABITS IN TIMES OF THE COVID-19 PANDEMIC
Authors: Cámara Hurtado Mª Montaña
Published: July 2021

The first challenge we face in this 21st century is to be able to feed all the inhabitants of this planet with safe and healthy food in a sustainable way. There are societies where the main problem is the availability of food, which leads to malnutrition and diseases of poverty (mainly communicable). In other societies, the availability of food is not the problem, but paradoxically there are cases of malnutrition due to poor dietary choices, which lead to the so-called wealth diseases (non-communicable), such as cardiovascular diseases as the main cause of mortality. The emergence at the beginning of 2020 of the emergency caused by the SARS-Cov2 coronavirus has made this situation a new challenge throughout the world, without distinction of countries with high or low income. The speech aims to address the importance of maintaining an adequate nutritional status to maintain good health, minimize the negative effects caused by COVID-19 as well as facilitate the recovery of patients. Scientific evidence regarding the role of micronutrients and bioactive compounds in strengthening the immune system will be reviewed, a synergistic beneficial effect based on their complementary mechanisms of action. It will also discuss the new concept of “planetary health diet” that considers the relevance of dietary choices, due to their implication for both human health and the environment, while maintaining available resources: water, land and soil. The ultimate goal is to deepen scientific knowledge so that it can be of use to society; promoting food security through healthy and sustainable eating.
AUGMENTED REALITY PEMBELAJARAN PRAKARYA INTERAKTIF UNTUK MATERI KETERAMPILAN DARI LIMBAH SAMPAH ANORGANIK (STUDI KASUS DI SMP MARHAS MARGAHAYU)
Authors: Sifa Maesaroh Siti , Gusdevi Harya , Reksa Ariansyah Muhammad
Published: July 2021

Teknologi augmented reality merupakan aplikasi penggabungan dunia nyata dengan dunia maya dalam bentuk dua dimensi maupun tiga dimensi yang diproyeksikan dalam sebuah lingkungan nyata dalam waktu yang bersamaan. Saat ini augmented reality dapat dijadikan sebagai media pembelajaran sehingga pembelajaran lebih menarik, interaktif dan menyenangkan, seperti halnya aplikasi yang dibangun ini yaitu aplikasi pembelajaran prakarya interaktif menggunakan augmented reality khususnya untuk materi keterampilan dari limbah sampah anorganik. Kesulitan muncul ketika dalam penyampaian materi seperti penyampaian langkah-langkah pembuatan kerajinan tersebut masih menggunakan buku dan pengalaman guru. Maka diperlukan sebuah aplikasi pembelajaran interaktif yang memanfaatkan teknologi augmented reality.
Habilidad competitiva entre plantas de festuca alta libres e infectadas con hongo endófito bajo cosecha.
Authors: Petigrosso Lucas Ricardo , Martinez Verneri Julieta , Fernández Osvaldo Néstor
Published: July 2021

Dado el aumento de la incidencia del endófito Epichloë coenophiala en pasturas de festuca alta y el consecuente riesgo de intoxicación del ganado por festucosis, resulta importante comprender qué papel juega la competencia entre plantas infectadas (E+) y libre de endófito (E-) en interacción con la defoliación, en el aumento de la frecuencia de E+ sobre E-. Se realizó un experimento de competencia de tipo sustitutivo en macetas a campo. Se emplearon 4 genotipos de festuca E+ y E- (remoción con fungicida y clonación). Los clones E- y E+ fueron utilizados en tres niveles de tratamiento: monoculturas E+E+, monoculturas E-E- y mezclas 1:1 E+E-, a densidad constante de 8 plantas/maceta (2 por genotipo), combinados con dos niveles de defoliación (sin y con corte mecánico). Los cortes de biomasa aérea se efectuaron cada 2 semanas a 3 cm del suelo. La simbiosis endófito-festuca no se tradujo en una mayor biomasa aérea de las monoculturas E+E+ respecto a las E-E-, independientemente del tratamiento de corte. En el tratamiento testigo sin defoliación, las monoculturas E-E- produjeron mayor biomasa que las E+E+, sugiriendo un costo neto de la asociación simbiótica en esta condición. Cuando ambos fenotipos crecieron en mezclas 1:1, las plantas E+ se comportaron como dominantes, de acuerdo a los índices de competencia estimados. Contrariamente a los esperado, ni los cortes periódicos ni la provisión de condiciones de crecimiento sin restricciones de recursos, neutralizaron los efectos positivos de la simbiosis sobre plantas E+, creciendo en mezcla 1:1 con plantas E-. La incidencia de infección en mezclas E+E- tendería a aumentar, al menos en condiciones favorables para el crecimiento de las plantas y en ausencia de otros herbívoros que podrían ser disuadidos por plantas E+.
Phylogenetic relationships of Argentinean Creole with other Latin American Creole Cattle as revealed by a medium density Single Nucleotide polymorphism microarray
Authors: Raschia Maria Agustina , Poli Mario
Published: July 2021

The demographic history of Creole cattle in Argentina and in Latin America dates back to the time of the Spanishcolonization. This study aimed to investigate the potential use of a medium­density SNP array to describe cattlefromthe most representative andoldest herds of the Argentine Creole cattle breedregisteredat the time of theconstitution of the Argentinean Creole Cattle Breeders Association and to explore the phylogenetic relationship withCreole cattle fromother LatinAmericancountries. Toachieve this goal, genotypes from51 animals on34,008autosomal SNP were used to generate genetic distance matrices based on the proportion of shared identical­by­statealleles among individual animals and animals clustered according to their origin, analyzed by the PLINKprogram.Aneighbor­joining phylogenetic tree based on pairwise genetic distance was constructed using PHYLIP and wasprepared for visualization using FigTree. Amultidimensional scaling analysis was performed to evaluate the levelof relationship in terms of genetic distance among the different animal clusters. Genetic distances between animalsvaried from0.186 to 0.357 when considering all pairs of animals, and from0.186 to 0.338 when considering Creolepairs. The dendrogramobtained showed three major clusters. Cluster 1 included Latin American Creole cattle fromColombia, Guadalupe, Paraguay, and Uruguay, and the reference groups of Holstein and Jersey cattle. Cluster 2contained exclusively Patagonian Creole cattle, while the third cluster included the remaining Argentinean Creoles.The genetic relationship patterns obtainedvia multidimensional scaling showeda close relationship among fourgroups of Creole animals fromArgentina. The closeness between clusters can be explained in part on the basis ofearly migration of animals that gave rise to founders herds at some Argentinean locations. The outcomes of thisstudycontribute toabetter understandingof the compositionof the earlyfounder herds of Creole cattle inArgentina and the relationship with other Latin America Creole cattle populations.
Analisis Kelebihan dan Kekurangan dalam Pembelajaran Daring di SDN Pesanggrahan 01 Kota Batu Malang
Authors: Nurkholis Irfan
Published: July 2021

Pandemi covid-19 yang semakin tidak terkendali penyebarannya, mengakibatkan pembelajaran yang selama ini berlangsung secara normal menjadi terganggu. Pemerintah dipaksa mengambil langkah dalam proses pendidikan dengan melaksanakan pembelajaran secara online (daring) dari rumah. Pembelajaran secara daring adalah salah satu alternatif yang diharapkan dapat mengatasi masalah tersebut. Disisi lain sistem pembelajaran ini menuntut siswa memiliki fasilitas yang tepat guna mendukung pembelajaran yang sesuai. Tujuan penelitian adalah untuk memperoleh gambaran kelebihan dan kekurangan pembelajaran daring yang dilaksanakan di SDN Pesanggrahan 01 Kota Batu. Berdasarkan data di lapangan penggunaan teknologi belum maksimal dilihat dari beberapa kondisi guru yang berusia lanjut. Kondisi lain, masih banyak siswa yang tidak memiliki gawai untuk mengikuti pembelajaran daring karena ekonomi atau orangtua yang bekerja sepanjang hari. Metode penelitian yang digunakan adalah pendekatan kualitatif dengan jenis penelitian deskriptif. Responden yang digunakan sebagai data penelitian sebanyak 14 tenaga pendidik. Dari hasil penelitian ini dapat disimpulkan bahwa kelebihan pembelajaran daring lebih banyak dibandingkan kekurangannya. Inovasi dan perbaikan pembelajaran diperlukan untuk meningkatkan kualitas pendidikan.
Social Change and the Culture as the Basic of Wulandoni-Pantai Harapan Reconciliation
Authors: Konradus Blajan , Dasion Agustinus Gergorius Raja
Published: July 2021

This study aims to explain social change of post-conflict of the Wulandoni - Pantai Harapan community and what kind of cultural communication space should be built for sustainable reconciliation and peace. The two focus studies above have become very central in reading and analysing the reality of the conflict between the two villages. By using ethnographic method, this study found three things. First, the conflict between Wulandoni and Pantai Harapan villages is not a religious conflict. Even so, it cannot be denied that the discourse on religious conflict was quite developed at that time because the cultural and religious realities of the two villages were quite different. Second, the Wulandoni-Pantai Harapan conflict caused social change and the loss of kinship between the people, especially the loss of the Wulandoni barter market. Third, post-conflict reconciliation and peace efforts are immediately carried out thanks to the cultural and economic relations between the people on the south coast of Lembata Island. These social, economic and cultural kinship relationships are important pillars in creating peace and harmony between communities. This study also opens the discourse of reconciliation and peace based on local culture and economy in the south of Lembata Island.
The Dangers of Hoaxes in Building Civil Society in the Era of the Industrial Revolution 4.0
Authors: Gus Rijal Muhamad Basitur Rijal , Hisam Ahyani , Basit Abdul
Published: July 2021

Civil society (civil society) as the ideal structure of society's life that is aspired to, but building a civil society is not easy. There are preconditions that must be met by the community in making it happen. Coupled with technological advances in the era of the Industrial Revolution 4.o like today, where information can spread easily through various online media unlimitedly in spreading hoaxes. This research seeks to uncover the dangers of hoaxes in building civil society. This research uses descriptive analytical method by examining the sources of literature related to building civil society in the Industrial Revolution 4.o. This research found that the public space is a means of free speech; democratic behavior; tolerant; pluralism; and social justice can shape civil society. whereas the impact of hoax news greatly affects the way people perceive a certain issue, so that people cannot distinguish which news is real or fake news which causes them to be incited by fake news that is spread.
Localized SPR for Pb(II) ion sensing utilizing chitosan/reduced graphene oxide nanocomposite
Authors: Abdullah Suraya , Azeman Nur Hidayah , Kamaruddin Nur Hasiba , Mobarak Nadhratun Naiim , A Bakar Ahmad Ashrif
Published: July 2021

In this work, a simple and highly sensitive localized surface plasmon resonance (LSPR) technique had been developed for detection of Pb(II) utilizing chitosan/reduced graphene oxide (CS/rGO) nanocomposite as the sensing material. Gold nanoparticles (AuNP) had been incorporated with the nanocomposite material to induce strong LSPR responses. CS/rGO nanocomposite was coated on top of AuNP and had been utilized as active layer for Pb(II) ion sensing. The morphology and physical properties of gold nanoparticle-chitosan/reduced graphene oxide (AuNP-CS/rGO) nanocomposite was studied using field-emission scanning electron microscopy (FESEM), atomic force microscopy (AFM) and x-ray diffraction (XRD) analysis. FESEM exhibits a rough and wrinkle surface of AuNP-CS/rGO after the addition of rGO. AFM shows a higher surface roughness for AuNP-CS/rGO due to the presence of oxygen atoms in rGO where these oxygen atoms provide more sites for adsorption of Pb(II), hence enhance the sensitivity of the sensor. A good sensitivity of the LSPR sensor for detection of Pb(II) utilizing AuNP-CS/rGO was obtained which is 1.544 ppm-1 and the linearity of the sensor are 0.99 and 0.97. In stability study, AuNP-CS/rGO exhibits a good repeatability with relative standard deviation of 2% for 0.01 ppm.
Gestão da inovação: indicadores para empresas de base tecnológica de pequeno porte – modelo Inov-EBTPP
Authors: Jesus Silvia Manoela Santos de , Oliveira Junior Antonio Martins de , Pena Felipe Gouvêa
Published: July 2021

Este artigo tem como objetivo construir um modelo de inovação para empresas de base tecnológica brasileiras de pequeno porte do segmento industrial. São apresentadas discussões conceituais sobre gestão de inovação, indicadores e modelos de inovação, utilizando-se para justificar as análises encontradas neste estudo. A pesquisa foi caracterizada como exploratória e descritiva com uma abordagem qualitativa e quantitativa. Foi realizada uma busca de informações utilizando-se da revisão bibliográfica, pesquisando artigos contendo modelos de indicadores de inovação, a partir de dados secundários, como PINTEC, Radar da Inovação (SEBRAE) e Bússola da Inovação (Paraná). Como resultados obtidos, este estudo atendeu ao seu objetivo inicialmente proposto que foi o de construir um modelo de indicadores apropriado para as empresas de base tecnológica de pequeno porte (Inov-EBTPP), com orientação de mensuração do Foresight de Andersen e Andersen (2014).
COVID-19 “La Piel Se Expresa” Comportamiento en la Población Pediátrica
Authors: Caballero Castro Héctor Rubén , Oliva Melida de Jesús Galeas , Díaz Guifarro María Fernanda
Published: July 2021

La situación actual en Honduras y a nivel mundial ha cambiado drásticamente con la aparición de un nuevo tipo de coronavirus que produce el Síndrome Respiratorio Agudo Severo (SARSCoV-2) (Covid 19). Lo que inicialmente se creía causaba sintomatología similar a un simple resfriado u otras patologías respiratorias virales comunes, ha evolucionado y ocasionado daños catastróficos con innumerables pérdidas humanas y económicas. Muchas han sido las formas de presentación del reciente coronavirus, el cual ha demostrado en múltiples reportes de casos a nivel mundial que ataca diferentes sistemas; como ser el gastrointestinal, respiratorio, cardíaco y cutáneo en los diferentes grupos etarios.

No obstante, el cuadro que aparece en algunos casos de población pediátrica es mucho menos severo, con manifestaciones muy leves como rinorrea, congestión nasal, fatiga, fiebre, tos, entre otros.(1) También hay reportes de casos de COVID-19 positivo que inicialmente manifestaron una erupción cutánea sin síntomas respiratorios; éstos cuadros cutáneos podrían ser el preludio de un paciente infectado y ante ésta sospecha, se puede prevenir la transmisión de la enfermedad; así́ como también establecer el diagnóstico y tratamiento oportuno
Percepción de factores modiicables que afectan la educación médica en Honduras: Encuesta 2019.
Authors: Solano Velásquez Jhiamluka Zservando
Published: July 2021

Antecedentes: El sistema de salud en Honduras contribuye de manera importante a la formación médica, facilitando espacios, talento humano y pacientes. Objetivo: Describir la percepción de médicos en formación y docentes sobre factores que pueden afectar la educación médica y la seguridad del paciente, Honduras, 2019. Métodos: Estudio descriptivo transversal con análisis de asociación, en estudiantes de grado/postgrado y docentes, Carrera de Medicina de tres universidades. Se estimó muestra aleatoria. Se realizó encuesta mediante plataforma web disponible durante una semana. Resultados: Se contó con un total de 324 participantes, 205 (63.3%) estudiantes de grado (7mo y 8avo años), 102 (31.5%) estudiantes de postgrado y 17 (5.3%) docentes; 53.4% (173) pertenecía al género femenino. De los estudiantes, 33.9% (104) informó sufrir acoso sexual, 36.8% (113) sufrir sanciones no reglamentadas, 47.9% (147) realizar procedimientos no enseñados y sin supervisión. El 58.8% (10) de los docentes consideró que el tiempo estipulado para enseñar no es suiciente en contraste con otras obligaciones docentes. El 42.3% (130) de los estudiantes y 11.8% (2) de los docentes presentaron Síndrome de Burnout severo. La sobrecarga laboral se asoció a no adquirir nuevas habilidades en estudiantes de 7mo año (OR 2.5, IC95% 1.2-3.7, p=0.02) y a faltar a clases mandatorias en estudiantes de 7mo año y residentes en un 75.1% (OR 3.4, IC95% 2.82-3.98, p=0.05). Discusión: La sobrecarga laboral, el acoso sexual y laboral, las sanciones no reglamentados y el Síndrome de Burnout son factores que al modiicarlos pueden contribuir a una impostergable mejora de la educación médica en Honduras.
COVID-19 en América Latina y Caribe: Determinación de prioridades en investigación y llamado a la acción
Authors: Feune de Colombi Nicole , Bueno Flavia , Alger Jackeline , Baker Bonny , Canario Julio , Mestra Laureano , Osorio Lyda , Solar Hormazabal Orielle , Soriano Mario E. , Matta Gustavo , Lang Trudie , Soto Ramón J.
Published: July 2021

Antecedentes: La Red de Salud Global estableció, en enero 2020, una comunidad de práctica para abordar la investigación en COVID-19 en países de ingresos bajos/medios. Objetivo: Identificar prioridades en investigación sobre COVID-19 que requieren atención urgente en América Latina y el Caribe (LAC) y establecer una comunidad de práctica abierta local para apoyar su implementación. Métodos: Estudio exploratorio mixto. Se analizaron los resultados específicos para LAC de una encuesta en línea (enfoque cuantitativo) que evaluó si la agenda prioritaria de investigación para COVID-19 de la OMS sigue siendo pertinente solicitando a los participantes que clasificaran sus tres principales prioridades a corto y largo plazo. Asimismo, se organizó un taller virtual abierto (enfoque cualitativo) el cual fue grabado. Se realizó un análisis temático pragmático a partir de las presentaciones de los panelistas y de las preguntas y comentarios de la audiencia. Se generó un marco de codificación mediante enfoques inductivo y luego deductivo siguiendo la agenda OMS. Resultados: Se contó con 223 participantes de 22 países. Se identificó un consenso sobre los temas de investigación e innovación prioritarios para LAC, dentro y fuera del marco de la agenda OMS, siendo una gran prioridad la necesidad de estudios de ciencias sociales para ayudar a los científicos biomédicos. Discusión: Dado que los casos siguen aumentando en LAC, consideramos que nuestros hallazgos son útiles para orientar tanto a las redes de investigación en la planificación de estudios como a los financiadores en sus decisiones para la asignación de recursos para investigación e innovación.
Resultado oncológico de cirugía conservadora con adyuvancia en cáncer de mama, Hospital San Felipe, Tegucigalpa
Authors: Lozano Chicas Lylian Karina , Jerez Roberto , Alger Jackeline
Published: July 2021

Antecedentes: El cáncer de mama es la malignidad más frecuentemente diagnosticada en mujeres, representando casi 1 de cada 4 casos de cáncer. Objetivo: Describir los resultados oncológicos de las pacientes tratadas con cirugía conservadora y adyuvancia por cáncer de mama estadios clínicos I-II, Hospital San Felipe, Tegucigalpa, 2017-2019. Métodos: Estudio descriptivo transversal retrospectivo. Extracción de información de expedientes clínicos de pacientes con diagnostico nuevo de cáncer de mama. Se registró datos sociodemográficos, estadio clínico pre- y post-operatorio, tratamiento y sobrevida. Resultados: De 49 pacientes, 59.2% (29) >50 años, 71.4% (35) procedencia urbana, 61.2% (30) estadio IIA, las modalidades terapéuticas fueron radioterapia 73.5% (36), hormonoterapia 69.4% (34), quimioterapia 40.8% (20). La combinación más frecuente fue radioterapia/hormonoterapia 46.9% (23); 26.5% (13) recibió monoterapia. El tiempo promedio de inicio de radioterapia fue 25 semanas (rango 4-90 semanas) y 13 semanas (rango 4-35 semanas) para quimioterapia. La sobrevida a 36 meses en estadio IA y IIB con adyuvancia fue 100.0% (5) y 86.0% (12), respectivamente. La sobrevida global a 36 meses fue 95.9% (47). Discusión: La sobrevida global identificada es comparable a estudios que siguen las guías internacionales. Recomendamos implementar las recomendaciones de las guías internacionales para el manejo de cáncer de mama estadios tempranos, donde la adyuvancia debe iniciar en un periodo no mayor a 8 semanas postoperatorias. Este manejo contribuiría a reducir la morbilidad y el impacto psicosocial que presentan abordajes terapéuticos más radicales. Es necesario y urgente contar con equipo y medicamentos adyuvantes de acuerdo a los avances científicos y tecnológicos.
Perfil de riesgo en fallecidos por infarto agudo de miocardio en atención pre-hospitalaria: 2017-2019
Authors: Carballo Jimmy Alonso , Martínez Abrantes Maidy , Almanza PuertO Neivys , Martínez López Yusleikis , Herranz Molina Mailyn , Gómez Gutierrez Mayelín
Published: July 2021

Antecedente: El infarto miocárdico es un problema de salud global. El conocimiento del peril de riesgo podría contribuir a planiicar intervenciones sobre todo en la atención primaria. Objetivo: Describir el peril de riesgo en fallecidos por infarto miocárdico en la atención pre-hospitalaria en Florida, Cuba entre 2017 y 2019. Métodos: Se realizó un estudio descriptivo retrospectivo de los 53 fallecidos por infarto miocárdico en la atención pre-hospitalaria en el municipio Florida. Los datos se obtuvieron del registro de fallecidos, historias clínicas, y de la autopsia verbal realizada a familiares. Resultados: Predominaron los hombres con 67.9% (36), el color de piel blanca 35.8% (19) y el grupo de edad entre 60 a 69 años 30.2% (16). El edema agudo del pulmón representado por 37.8% y la insuiciencia cardiaca 24.3%, fueron las complicaciones más frecuentes. La mayoría de los pacientes fallecieron en domicilio 35.9% (19) y el 22.6% (12) fallecieron en traslado no sanitario hacia hospitales. Procedían de áreas urbanas 56.6%. La hipertensión arterial 73.6%, el tabaquismo 66.0%, y obesidad 52.8% fueron los factores de riesgo modiicables más identiicados. Tener más de 3 factores de riesgo y mayor demora en ser admitido inluyó negativamente en la sobrevida. La mortalidad fue signiicativamente mayor en los pacientes con elevación del segmento ST en 74.2%. Discusión: Existió un comportamiento similar al revisado en la literatura en cuanto a riesgos y tiempo en llegar al hospital. La atención pre-hospitalaria al IAM es el punto más crítico en el abordaje de esta entidad.
Discapacidad y su atención por personal sanitario en hospital de tercer nivel en Honduras
Authors: Sierra José Elpidio , Zelaya Jenny , Ramírez Andrea , Gonzales Mauricio , Sierra Leonardo , Alger Jackeline , Maradiaga Edna
Published: July 2021

Antecedentes: El 25% de hospitalizaciones pueden requerir rehabilitación y en Honduras la discapacidad en hospitales no ha sido considerada. Objetivo: Determinar proporción de discapacidad en pacientes hospitalizados y conocimientos, actitudes y prácticas (CAP) del personal sanitario en discapacidad/rehabilitación, Hospital Escuela, agosto 2016. Métodos: Estudio descriptivo transversal, en pacientes mayores de 18 años hospitalizados aplicándoles cuestionario World Health Organization Disability Assessment Schedule (WHODAS) para identiicar discapacidad. Al personal de salud se le aplicó instrumento para identiicar CAP de rehabilitación en personas con discapacidad. Se realizó análisis univariado; se obtuvo consentimiento informado escrito. Resultados: De 235 pacientes, 86.8% (204) tenía discapacidad. De éstos, 68.1% (139) edad 18-59 años, 53.4% (109) sexo femenino, 57.8% (118) discapacidad moderadacompleta. Sólo en 5.4% (11) se solicitó interconsulta con Servicio de Rehabilitación tras una semana desde ingreso. De 114 participantes del personal sanitario, 50.9% (58) tenía conocimiento deiciente; enfermeras profesionales 60.9% (14) y auxiliares de enfermería 75.0% (30); actitudes fueron positivas excepto reconocer no manejo integral en pacientes 50.9% (58), médicos especialistas 30.4% (7) y 32.1% (9) médicos residentes. De 9 prácticas evaluadas, 4 fueron menos realizadas: postura antiequino, liberación de prominencias óseas 39.5% (45), respectivamente; manejo de cavidad oral 50.0% (57), sedestación en cama 50.9% (58); menos realizadas por médicos residentes 54.6% y auxiliares de enfermería 58.5%. Discusión: Existe alta proporción de discapacidad con pobre respuesta posiblemente derivada de conocimiento deiciente y baja realización de buenas prácticas en rehabilitación. Debe capacitarse al personal sanitario en reconocer la discapacidad y mejorar trabajo en equipo con Servicio de Rehabilitación. Palabras claves: Clasiicación Internacional de Funcionamiento de la Discapacidad y de la Salud, Evaluación de la discapacidad, Honduras, Pacientes internos, Persona con discapacidad.
Desertificação em Gilbués – Piauí: uma possível abordagem a partir da História Ambiental
Authors: Macambira Dalton Melo , Gomes Jaíra Maria Alcobaça
Published: July 2021

A desertificação é um dos maiores problemas ambientais do mundo na atualidade. Nesse sentido, pretende-se estudar a história da desertificação em Gilbués, localizado no sudoeste piauiense, numa região de transição entre a caatinga e o cerrado. O início da degradação dos solos na região começou nos anos de 1940 e 1950, embora existam registros de fragilidades ambientais desde a segunda metade do século XIX. O objetivo do trabalho é demonstrar as possibilidades de se estudar o processo de desertificação em Gilbués a partir da teoria e da metodologia da história ambiental, pensando a partir das interações entre sociedade e natureza ao longo do tempo. A pesquisa, a partir dos pressupostos da história ambiental, pressupõe três níveis: 1) investigar os recursos naturais existentes na área de estudo; 2) analisar as relações socioeconômicas da sociedade com o ambiente ao longo do tempo; 3) compreender as manifestações culturais resultantes das interações do homem com a natureza. Neste ensaio, do ponto de vista metodológico, utilizar-se-á as duas primeiras dimensões. Para tanto, serão apresentados os principais teóricos dessa nova abordagem historiográfica e far-se-á revisão de literatura sobre o fenômeno da desertificação.
Geotechnical Engineering for Mass Mining
Authors: van As Andre
Published: July 2021

Editor’s note: The Geology and Mining series, edited by Dan Wood and Jeffrey Hedenquist, is designed to introduce early-career professionals and students to a variety of topics in mineral exploration, development, and mining, in order to provide insight into the many ways in which geoscientists contribute to the mineral industry.

The rock mass response to mining is governed by the rock mass characteristics and the mining-induced changes that drive its behavior. To be able to study and accurately predict the response of the rock mass to mining, it is imperative that both the orebody and the enclosing country rocks are well characterized through the collection and analysis of large quantities of good-quality, representative geologic, structural, geotechnical, and hydrogeological data. These are the fundamental constituents of a good geotechnical model whose reliability improves as the mining project matures and moves from exploration and study phases, passes the decision to develop, and proceeds into construction and then operations. Each phase provides greater exposure to the rock mass, reduces uncertainty, and increases reliability in the geotechnical model and in an understanding of the rock mass behavior. The quest of the geotechnical engineer is to understand the rock mass behavior and is no different from that of the geologist who defines the mineral resource, and it warrants (at the very least) the same level of rigor in data collection, analysis, and reporting. Just as the geologist continues to improve the orebody model through grade reconciliation during mining, so the geotechnical engineer must continually revisit and calibrate the geotechnical model during the operational phase of mining through geotechnical monitoring. The increasing demand by investors and stakeholders that the performance of a mine does not deviate from plan due to unforeseen geotechnical surprises warrants a significant shift in the level of geotechnical data collection, analyses, and rock mass monitoring through all stages of study and operations. This demand warrants supporting budgets and assurance processes that are commensurate with the complexity and extent of the geotechnical uncertainties.
The Social Dimensions of Mineral Exploration
Authors: Mackenzie Sarah , Everingham Jo-Anne , Bourke Pam
Published: July 2021

Editor’s note: The Geology and Mining series, edited by Dan Wood and Jeffrey Hedenquist, is designed to introduce early-career professionals and students to a variety of topics in mineral exploration, development, and mining, in order to provide insight into the many ways in which geoscientists contribute to the mineral industry.

Geoscientists are often the first point of contact a local community has with a company conducting mineral exploration. The behavior of the geoscientists and the interest they take in understanding the local community and stakeholders will have ramifications well beyond their direct exploration activities. This article highlights some of the positive and negative impacts exploration can have for local communities (in part drawing on interviews with experienced geoscientists and others involved in exploration). The article explores the increasing complexity of deposits in terms of environmental, economic, social, and political parameters and the increasing scrutiny by local stakeholders and the international community. We argue that, although geoscientists are not social performance specialists, they still need the awareness, tools, and capabilities to understand and manage the social aspects of their exploration activities commensurate with the stage and resourcing of the project. We propose three interrelated aspects of social performance that can be applied during mineral exploration: meaningful and positive engagement, acquiring and documenting a social knowledge base, and strategic investment in the community. Two case studies provide cautionary examples of failure to do so and two case studies highlight how, through careful engagement and strategic collaboration, mutually beneficial and positive relationships can be built from early exploration.
Impact of the COVID-19 Pandemic on the Minerals Sector: A Real Time Survey
Authors: Hitzman Murray , Kaeter David , Doran Aileen , Boland Maeve , Zhou Lingli , Drejing-Carroll David , Tsuruoka Subaru , Johnson Sean , Burke Siobhan , Stratford James , Brady Aoife , McAuliffe Fergus
Published: July 2021

Through the implementation of an online survey, run at the end of April 2020, researchers at the Irish Centre for Research in Applied Geosciences (iCRAG) explored the immediate effects of the COVID-19 pandemic on the minerals sector workforce. With more than 1,000 respondents, the survey provides insights into the impact of an unprecedented global event at a crucial point in its development. Seven weeks after the World Health Organization’s declaration of the pandemic, 65% of survey respondents agreed that COVID-19 had a significant impact on their work. Overall, 32% of respondents had experienced negative impacts on their employment, having either lost their jobs or been furloughed/temporarily laid off, or were working reduced hours.

Geographically, the greatest impact on employment was in Africa, where 45% of respondents suffered negative effects. More often, younger respondents (ages 18–30) reported lost jobs (14%) whereas older survey participants reported working reduced hours (21%, ages 46–60). Respondents working in mineral exploration were most affected (40% suffered negative job impacts), but the impact across base, industrial, and precious metals was broadly similar for all participants; government employees were least affected but were not immune (10% on reduced hours). The level of concern about future job security due to the COVID-19 crisis varied, with 35% of respondents being more or very concerned or having already lost their jobs, 43% had little or no concern, and 22% were moderately concerned. The survey captured the experiences and perceptions of individual workers, providing a perspective different from information available in corporate statements and official statistics.
Crowdfunding: New Financing Tool for Social and Solidarity Economy in Morocco
Authors: Sahmi Reda , El Hachloufi Mostafa , Aboulethar Meriem
Published: July 2021

Alternative forms of financing have emerged recently, such as solidarity finance, crowdfunding and participatory finance. They provide innovative solutions to the financial problems faced by economic agents wishing to carry out projects with significant social and environmental impact.In fact, these alternative forms of financing aim at proposing unprecedented alternatives and complementary financing offers that can help the actors of Social and Solidarity Economy (SSE) to concretize their projects. For this purpose, we are developing an analysis of the major assets and the distinguished opportunities that Crowdfunding will bring to SSE actors in Morocco. We will also examine how it can become one substitute of classical finance in Morocco.
Recurrence of Epidural Spinal Sarcoidosis
Authors: Magdon Louis A. , Elliott Robin , Cheng Christina W.
Published: July 2021

Neurosarcoidosis involving the spine is uncommon. Sarcoidosis of the spine usually presents as an intramedullary lesion and rarely an epidural lesion. To have recurrence of neurosarcoidosis is an even rarer presentation. Here, we present a 37-year-old man with poorly controlled sarcoidosis who initially presented to our medical center in 2015 with thoracic myelopathy from epidural spinal sarcoidosis treated with thoracic decompression and fusion. He presented to the hospital 5 years later with a month history of progressive upper extremity weakness. MRI revealed recurrent stenosis and spinal cord compression in the cervicothoracic junction. Urgent surgical intervention along with medical management resulted in symptomatic and functional improvement. Surgical intervention and compliance with postoperative corticosteroid therapy seem to yield a favorable prognosis for patients with epidural spinal sarcoidosis and to avoid recurrence.