bluuebunny/crossref_metadata_2025 huggingface dataset:
شیكردنەوەی باری دەروونیی ئاخێوەر لە زمانەوانیی دەروونیدا
Authors: ئەمیر موحەممەد موحەممەدئەمین
Published: September 2023

ئەم توێژینەوەیە بە ناونیشانی (شیكردنەوەی باری دەروونیی ئاخێوەر لە زمانەوانیی دەروونیدا)یە، توێژینەوەكە لە ڕوانگەی زمانەوانیی دەروونی كارەكەی ئەنجامداوە. ڕێبازی توێژینەوەكە، پەیڕەوكردنی ڕێبازی وەسفی شیكارییە بۆ لێكدانەوە و شیكردنەوەی دەربڕینە زمانییەكان. سنووری توێژینەوەكە لە چوارچێوەی دیالێكتی ناوەڕاستی زمانی كوردیدایە و گرنگیەكەشی لەوەدایە، كە باری دەروونی ئاخێوەری زمانی كوردی لە كاتی دەربڕینە زمانییەكاندا شیدەكاتەوە، كە لە چ دۆخێكی دەروونیدایە، چونكە دەربڕینە زمانییەكان كاتێ لە دەمی ئاخێوەر دەردەچن، سەرەڕای ئەوەی ژمارەیەك فۆڕمی زمانی لەخۆگرتووە، بەڵام ئەم فۆڕمە زمانییانە لە هەمان كاتدا بارگاوین بە باری دەروونی ئاخێوەرەوە.

 لەم توێژینەوەیەدا گریمانەی ئەوە دەكرێت، كە دەربڕینە زمانییەكان دەبنە هۆی ئەوەی، كە باری دەروونیی ئاخێوەر بزانرێت، كە لە چ دۆخێكی دەروونیدایە.

   ناوەڕۆكی توێژینەوەكە سەرەڕای هەبوونی پێشەكی و ئەنجام و سەرچاوەكان و پوختەیەك بە زمانی عەرەبی و ئینگلیزی، لە دوو بەش پێكهاتووە:

  بەشی یەكەم سەرەتا باسی هەندێ لایەنی ئاكار و سەرهەڵدانی زمانەوانیی دەروونی دەكات، كە بابەتەكانی زمانەوانیی دەروونی، سەرهەڵدانی زمانەوانیی دەروونی، پێناسەی زمانەوانیی دەروونی، گەشەسەندنی زمانەوانیی دەروونی، زمانەوانیی دەروونیی گەشەیی، زمانەوانیی دەروونیی ئەزموونی، ئاكارە گرنگەكانی زمانەوانیی دەروونی، دیاردەی دەروونی، واتای دەروونی لەخۆدەگرێت.

 لە بەشی دووەمدا باس لە شیكردنەوەی باری دەروونیی ئاخێوەر لە كاتی دەربڕینە زمانییەكاندا دەكات، كە بابەتەكانی پرۆسەی كاركردنی زمان، توانست و چالاكی لای چۆمسكی، ڕۆڵی زمانەوانیی دەروونی لە كۆمەڵی زمانیدا، ڕۆڵی زمانەوانیی دەروونی لە لای تاكەكەسدا، دەربڕینە زمانییەكان، باری دەروونیی ئاخێوەر لەخۆدەگرێت.
Narrative Analysis of the Iyezidi Chirok of Mir Mih : The Iyezidi Epic of Immortality
Authors: Lazgin Kheder Barany  , Rania Qaso
Published: September 2023

This paper aims at analyzing the Iyzidi religious narrative   of ‘Mir Meh ‘ , which is an epic of death and immortality according to the Iyzidi faith , using Labov Model (1972) of Narrative Analysis . The study has found out that the story of ‘Mir Mih’ is an eminent element of the Iyzidi religion and culture treating the issue of death and immortality. In addition to the linguistic devices used in the narrative as reflected by Labov (1972) , the narrative has moral and religious implications . It highlights the fact that the Iyzidi religion believes in the reality of life and death.  What makes this narrative distinguished is the idea of the return to the origin, which is one of the important aspects expressed in this narrative as ‘Mir Mih’ did not want to stay in Heaven but to go back to his people and home.  The study has also found out that Labov Model (1972), which consists of the following elements: abstract, orientation, complicating action, evaluation, resolution and coda ,  applies to the narrative under study
Journal of Pharmacy & Pharmacognosy Research: Bienvenida
Authors: Garrido Gabino
Published: September 2023

Open access is becoming increasingly evident, making the free access to texts a fact increasingly common. Also, the free availability of full scientific papers in electronic format on the Internet has proven to be the fastest and most effective way to disseminate or access to scientific information. Therefore, there is a boom in the creation of scientific journals available in online full text in most countries. However, in Chile there is little chance for pharmacists to publish their scientific work, given the lack of a journal to represent them. Arises is why the Journal of Pharmacy & Pharmacognosy Research, an international journal, in English and Spanish, specialized and peer review, open access, which publishes scientific studies in pharmacognostic and pharmaceutical fields. This journal will publish research articles, reviews, commentaries and letters to the editor, as well as special editions and reviews of book and undergraduate and graduate theses of pharmacists or professionals involved in Pharmaceutical Sciences or Pharmacognosy. The emergence of a scientific journal, plus an intellectual event, is a major financial and human challenge. We want to share this challenge with you, readers and future authors of the articles in this, your journal. Welcome!
enotoxic potential of BM-21, an aqueous-ethanolic extract from Thalassia testudinum marine plant
Authors: Ansoar Yadira , Díaz-Llera Silvia , Piloto Janet , Morffi Janet , Frión Yahima , Menéndez Roberto , Fernández Miguel David , Rodeiro Idania
Published: September 2023

Context: BM-21 is a hydro-ethanolic extract obtained from the leaves of Thalassia testudinum marine plant, which is rich in polyphenols, and it has demonstrated antioxidant, anti-inflammatory, cytoprotective and neuroprotective properties. Aims: To investigate the genotoxicity potential of BM-21. Methods: Salmonella typhimurium Hist. – strains were used in the pointmutation test and Escherichia coli cells were used in SOS response test. DNA primary damage was tested in hepatocytes of mice treated with oral dose of the extract (2000 mg/kg). Bone marrow micronucleus assay was used in mice to detect clastogenic damage while serum from the same animals was used to determine MDA levels in order to find out the influence of BM-21 on lipid peroxidation. Positive and negative controls were included in all experimental series. Results: BM-21 did not increase the frequency of reverse mutations in the Ames test, and it did not induce primary damage in E. coli. Comet assay showed that 2 000 mg/kg of BM-21 induced single strand breaks or alkali-labile sites in the hepatocytes from the treated mice. However, no increase in the micronucleus frequency was observed in mice polychromatic erythrocytes and significantly reduced MDA levels were detected. Conclusions: BM-21 was neither mutagenic nor induces DNA damage to prokaryotic cells. Although, it increased DNA strand breaks in vivo, this one was not translated into clastogenic damage to the whole organism. Results suggested that BM-21 was not mutagenic or genotoxic under our experimental conditions.
Mechanism of the negative inotropic effect of naringin in mouse heart
Authors: Alvarez-Collazo Julio , López-Medina Ana I. , Rodríguez Armando A. , Alvarez Julio L.
Published: September 2023

Context: Naringin (NRG) is the major flavonoid (flavanone glycoside) in grapefruit juice. Its biological activity has been only partially characterized and little is known about the mechanism of the negative inotropic action of this flavonoid. Aims: To evaluate the effects of NRG on the surface electrogram (ECG) and the force of contraction (FC) of mice hearts as well as on the sodium (INa), calcium (ICaL) and Na+ – Ca2+ exchange (INaCaX) currents of enzymatically isolated mouse ventricular cardiomyocytes. Methods: ECG and FC were recorded on mouse hearts perfused in a Langendorff column. Ventricular cardiomyocytes were enzimatically dissociated and ionic currents recorded with the patch-clamp technique. Results: NRG increased RR interval and shortened corrected QT only at high concentrations (30-100 µM). However, at a fixed heart rate, it decreased FC with an IC50 of 0.4 µM. NRG reduced INa with an IC50 of 0.07 µM but with a maximal inhibition of 60 %. NRG also depressed ICaL with an IC50 of 0.013 µM and increased its fast inactivation time constant. The effects on ICaL were not voltage-dependent. INaCaX was not affected by NRG. Conclusions: Our results indicate that NRG exerts a negative inotropic effect in mice hearts that could be explained by a decrease in INa and ICaL. These actions should be taken into account when considering this molecule either as a dietetic supplement or as a template to develop therapeutic agents for human diseases.
Acute and 28-day subchronic toxicity studies of mangiferin, a glucosylxanthone isolated from Mangifera indica L. stem bark
Authors: Prado Yalena , Merino Nelson , Acosta Jhoany , Herrera José A. , Luque Yilian , Hernández Ivones , Prado Elisa , Garrido Gabino , Delgado René , Rodeiro Idania
Published: September 2023

Context: Pharmacological properties of mangiferin have been reported, but few studies have investigated mangiferin toxicity. Aims: To study the acute and 28-day toxicity effects of mangiferin in rodents. Methods: Single doses of mangiferin were administered by oral or i.p. route or were applied dermally to Sprague-Dawley rats and Balb/C mice. Clinical symptoms of animals were observed during 14 days after treatment. Animals also received single oral doses daily for 28 consecutive days. Blood biochemistry, hematology and pathology findings were reported. Results: In the acute study, no toxic effects were observed after dermal exposure to mangiferin 2000 mg/kg but transient dyspnea, flank position and piloerection were observed after oral administration to this xanthone. I.p. administration induced similar toxicity signs, but at the highest dose (2000 mg/kg) all mice, one female rat and one male rat died. Rats orally treated with mangiferin (250-1000 mg/kg) for 28 days did not show any abnormal clinical signs or hematology alterations, when compared to control group animals. Histopathological alterations like vacuolar degeneration, necrosis and increment of apoptosis of the acinar cells were observed in the exocrine pancreas of rats at 1000 mg/kg. This suggesting that exocrine pancreas was the target organ for mangiferin’s toxicity. Conclusions: These studies indicated that acute and subchronic toxicities of mangiferin for oral exposure are low.
Evaluación de la irritabilidad dérmica y oftálmica de la formulación OLEOMASAJE
Authors: Díaz Maritza F. , García Kendra , Meneau Rosa I. , Sánchez Yaíma , García Gastón
Published: September 2023

Context: Ozonized vegetable oils present germicidal effects which can be used as active principle in different cosmetological compositions. The thematic about of the corporal massage advantage have been very treatment by aesthetics, dermatologic and consumers. OLEOMASAJE formulation content ozonized sunflower oil OLEOZON as active principle active which present moisturizer and conditioner effects. Aims: To determine the possible dermal and ophthalmic irritability effects of the OLEOMASAJE. Methods: The trial was conducted in rabbits and the techniques described in the standardized procedures of the work established by the Center of Biological Research and Evaluations from Pharmacy and Food Institute of Havana University were used according to Norma ISO 10993-10. The ethical principles of the Good Practices of Laboratory were fulfilled to avoid suffering to the animals during the experimentation. Male rabbits with body weight between 2.05 and 2.48 kg were used. In the skin and the ocular structures the effects were observed immediately after of the application at 1, 24, 48 and 72 hours. Draize´s scale was applied to evaluate skin and ocular structures lesions. Results: The OLEOMASAJE formulation does not irritate de skin of the assayed rabbits. However, the ocular structures irritability index was of 4.5 after of first hour to apply of product. These wounds were missing before of 24 hours to apply of product. Conclusions: The OLEOMASAJE formulation obeys the indispensable requirements for the acceptance as cosmetic product and for it is used in corporal massage.
Review on the Stock Investment in Malaysia in Overcoming the Inflation of the Malaysian Economy
Authors: Yeoh Wee Win
Published: September 2023

The purpose of the study is targeted to explore and investigate the potential performance of the stock investment in Malaysia in overcoming the inflation of the Malaysian economy. The primary goal of the investment is motivated to overcome the inflation rate to avoid losing the purchasing power. This leads to the problem statement for the study to investigate the performance of the KLSE market index growth against the inflation rate in Malaysia. The methodology of the research had focus in the application using past ten years of data including the range from 2013 to 2022 to compare the growth of the inflation against the KLSE market index. The findings had provided the sufficient evidence to showed that the inflation rate in average had exceed the KLSE market index growth reflecting that the investment in overall Malaysian stock is not favourable to overcome the increasing inflation in the country. In addition, the average Fixed Deposit (FD) rate in Malaysia had surpassed both the inflation rate and KLSE market index growth in average for the past ten years performance. The recommendation drawn from the study had proposed more solid management of the portfolio by not over diversifying the portfolio for the stock investment. The outcome for the study had provide the significant contribution and refenrece towards the academic and investors to gain future input.
Examining the Implications of Climate Change and Adaptation Technologies on the Livelihood of Cocoa Farmers in Offinso Municipalities, Ghanas
Authors: Elias Megbetor  , Boateng Solomon
Published: September 2023

Cocoa is highly sensitive to uncertainties in temperature and precipitation and is projected to be challenged by climate variability. This study examined the implications of climate change on the livelihood of cocoa farmers, and the adaptation technologies adopted to mitigate the impacts in the Offinso Municipalities. 210 cocoa farmers participated in the study, out of which 180 were selected randomly from the list of Kuapa Kokoo company. These people were interviewed with the help of questionnaires. The rest 30 were selected for focus group discussions held in two different communities. The study found deforestation, land degradation, and felling of trees for lumber and domestic fuel as the main causes of climate change. The socio-economic impacts were a reduction in crop yield and income, food insecurity, poor access to healthcare, poor water quality, drying up of streams, and reduction in labour supply. A positive revelation was that the farmers have realized a gradual increase in yield in the past three (3) years due to innovative measures adopted. Such innovations include agroforestry, good agricultural practices, crop diversification, frequent spraying, fertilizer application, adoption of hybrid varieties, and creation of fire belts. As a way of minimizing financial constraints, poor irrigation facilities, inadequate seed supply, and reduction in labour supply; the farmers receive some support from farmer organizations, the government, and cocoa companies. The study recommends that government institutions commit to the enforcement of laws on deforestation and illegal mining, ensure an effective supply of cocoa inputs, and promote adaptation measures in building farmer resilience in the study area.
NORBERT ELIAS’IN İLİŞKİSEL SOSYOLOJİK YAKLAŞIMI ÜZERİNE
Authors: BİLGİN Ayhan
Published: September 2023

Bu çalışmanın temel amacı öncelikle 1990'lı yıllarda gelişmeye başlayan ilişkisel sosyoloji ve sosyal bilim yaklaşımı
ile Norbert Ellias'ın ileri sürdüğü ilişkisel sosyolojik yaklaşımı ilişkilendirmektir. Bu amaçla çalışma, önce ilişkisel
sosyolojik yaklaşımı ana hatları ile ele almıştır. Burada beliren temel eleştiri sosyal olguların tözcü ve statik bir kavrayışla
ele alınmasıdır. Sosyal olgular ilişkisel bir varoluşa sahiptir ve ancak ilişkisel ve süreçsel kavram ve analiz
modelleri yoluyla anlaşılabilirdir. Bu tartışma ana hatları ile ele alındıktan sonra Norbert Elias'ın ileri sürdüğü temel
kavramlar bu ilişkisel yaklaşım bağlamında değerlendirilmiştir. Bu bağlamda karşılıklı bağımlılık, eklemlenme ve
figürasyon gibi temel kavramlar Eliascı ilişkisel analizin temel parçaları olarak belirmiştir. Elias'ın bu ilişkisel analiz
çerçevesi temelde tözcü ve statik sosyal analizleri aşmaya dönüktür. Birey ve toplum ilişkisi bağlamında Elias ikili
karşıtlıklara (birey-toplum, aktör-yapı, mikro-makro gibi) düşmeden karşılıklı bağımlılık ilişkilerini ve bunlara dayalı
etkileşim süreçlerini temel almıştır. Bu şekilde Elias'ın ilişkisel sosyolojinin temel argümanlarıyla uyumlu bir
ilişkisel çerçeve ortaya koyduğu görülmüştür.
Administración de la cartera impaga en la rentabilidad: una aplicación estadística clasificatoria en bancos
Authors: Navas Alcívar Silvia Janeth , Loor Solórzano Rosa María , López Solís Oscar Patricio , Haro Sarango Alexander Fernando
Published: September 2023

La gestión efectiva de la cartera de préstamos impagos es crucial para mantener la estabilidad y rentabilidad, especialmente en el ámbito financiero, esto destaca la importancia estratégica de una gestión rigurosa de los préstamos en mora para la salud financiera de las instituciones. Por la criticidad que adjudica la temática, se plantea como objetivo: proporcionar una interpretación integral y avanzada de cómo se encuentran los bancos en Ecuador desde la perspectiva de la morosidad y rentabilidad. Para el desarrollo de este análisis se evalúan los meses de enero a julio del 2023, datos disponibles en la Superintendencia de Bancos del Ecuador, el procesamiento empieza con mapas de calor de forma descriptiva, posteriormente, con el modelo Árboles de Decisión: el algoritmo CART. Aplicado el procedimiento metodológico se llega como resultado que, la rentabilidad de las instituciones bancarias en el presente entorno destaca la importancia prioritaria de gestionar cuidadosamente los microcréditos y de mantener un control adecuado sobre la morosidad promedio en la cartera total.
Concepciones de la democracia. Función estatal del Instituto Nacional Electoral, su contribución a la democracia y retos que enfrenta
Authors: Venegas Quintana Omar
Published: September 2023

El trabajo de investigación contiene una serie de reflexiones entorno el sistema electoral mexicano, la democracia moderna y el ejercicio de los derechos políticos; asimismo, entorno la función estatal del Instituto Nacional Electoral y aquellas consideraciones que son necesarias para su realización partiendo del constitucionalismo mexicano y sus aportes a la democracia. El objetivo del trabajo se desglosó en aras de fortalecer la cultura política democrática y en aras de reconocer que los consensos mayoritarios resultan insuficientes para legitimar decisiones. La estrategia metodológica se basó en aspectos y/o análisis cualitativos; aunque también se hizo referencia, citando a otro autor, del método comparativo respecto al derecho constitucional latinoamericano. El autor centró los principales hallazgos en valores y principios democráticos como la gran contribución del Instituto Nacional Electoral. Por lo anterior, el autor presentó dos conclusiones importantes: La primera, que deriva de esa contribución democrática teniendo a bien que los “valores democráticos” sólo se significan en el marco de un derecho institucional. Y, segunda, los retos que enfrenta hoy en día el órgano electoral mexicano tienen que ver, en efecto, con el correcto funcionamiento del Estado de Derecho. El autor también sostuvo el discurso de la extensión progresiva de los derechos políticos cuyos ejercicios están consolidados en la formación de la voluntad colectiva.
Analyzing The Influencing Factors Associated with Environmental Reporting in The Context of Green Accounting Implementation
Authors: M. Abdallah Huda
Published: September 2023

The research aims to analyze the influencing factors associated with environmental reporting in the context of green accounting implementation. The research is organized to present a discussion on green/environmental accounting, a literature review related to environmental reporting, and concepts, benefits, obstacles, and influencing factors associated with environmental reporting. The study methodology was based on a field survey the researcher directed the questionnaire to the stakeholders (investors, financial analysts, creditors, and auditors) of the Egyptian listed firms. Only 427 questionnaires with responses Were collected and included 11 incomplete questionnaires. Only 416 questionnaires were statistically valid and free of missing data, with a response rate of 88.89%. The researcher concluded that external and internal factors associated with environmental reporting have a significant direct positive impact on the benefits of environmental reporting. External and internal factors associated with environmental reporting have a significant direct negative impact on the obstacles of environmental reporting. Keywords: Environmental Reporting, Environmental Disclosure, Green Accounting.
Using GIS to Predict Areas of Cultural Resources Within the Walnut Canyon Study Area near Flagstaff, Arizona
Authors:   , Pernice Laura
Published: September 2023

Predicting locations of cultural resource in the Walnut Canyon Study Area near Flagstaff, Arizona was accomplished by using geostatistical and spatial analysis techniques of Directional Distribution, Kernel Density, and Average Nearest Neighbor. Known cultural resource sites within Walnut Canyon National Monument were analyzed to identify spatial patterns and densities to apply the results to the study area. Cultural resource sites are predicted to be highly clustered within 200 feet of fresh water sources as well as in woodland and shrub land vegetation types. Results can be used for land-use managers to identify areas to survey with high potential of containing cultural resources.
Reactivación y coinfecciones virales en COVID-19: otro elemento a considerar. Revisión Sistemática
Authors: Ponce-Pincay Roberto , Diana Callejas
Published: September 2023

La COVID-19 es una enfermedad que afecta a la población mundial, representando un reto social y sanitario. El SARS-CoV-2 muestra afinidad por el sistema respiratorio, por ser la puerta de entrada y el sitio primario de replicación. Aunque las manifestaciones respiratorias sean las más frecuentes, se han reportado manifestaciones gastrointestinales, renales, neurológicas, cardiacas; entre otras. Un elemento que no ha recibido en la atención que merece es la reactivación y las coinfecciones virales. Como es bien sabido, el tratamiento de COVID-19 en sus formas graves y críticas incluyen productos biológicos, corticoesteroides, ventilación mecánica y la múltiple farmacoterapia, aunado a la fisiopatología propia de la enfermedad que es caracterizada por una tormenta de citoquinas; conlleva a que se reactiven infecciones virales que se consideran latentes y crónicas, agravando aún más el cuadro clínico. En esta revisión sistemática se ha encontrado que eventos hematológicos como la leucopenia y linfopenia junto al uso desmedido de esteroides, y la larga estancia hospitalaria puede conllevar a la reactivación de virus que pertenecen a la familia Herperviridae (Virus Epstein-Barr (VEB), Citomegalovirus (CMV) y el virus del Herpes (VHS1/2)) así como virus hepatotropos (virus de la Hepatitis B (VHB) y C(VHC), que pueden complicar el pronóstico clínico
Hubungan komunikasi terapeutik dengan tingkat kecemasan pasien
Authors: Husada Imam Farid Farian , Andoko Andoko , Elliya Rahma
Published: September 2023

Pendahuluan :Kecemasan dapat menimbulkan beberapa gangguan psikologis antara lain bibir terasa kering, merasa kesulitan bernafas, merasa dalam suasana yang tidak nyaman, berkeringat meskipun cuaca tidak panas, jantung bedebar-debar, merasa sulit menelan, gemetar dan ketakutan. Apabila gangguan yang terjadi tidak diatasi dapat berpengaruh dalam memberikan asuhan keperawatan yang tepat dari perawat kepada pasien, Berdasarkan hasil prasurvey di RSUD Ahmad Yani Kota Metro Pada Bulan Maret 2019, dari 10 pasien pre operasi, 7 pasien mengatakan jantungnya berdebar-debar, merasa pusing, mengalami keringat dingin, dan tremor, sedangkan 3 pasien tidak mengalami gejala tersebut, hal ini menunjukan bahwa tingkat kecemasan pada pasien pre operasi masih relative tinggi.

Tujuan : dalam penelitian ini adalah diketahui hubungan komunikasi terapeutik perawat dengan tingkat kecemasan pada pasien pre operasi di RSUD Ahmad Yani Kota Metro Tahun 2019.

Metode :Jenis penelitian kuantitatif. Rancangan penelitian ini menggunakan analitik, dengan pendekatan cross sectional.Populasi dalam penelitian ini adalah pasien pre operasi RSUD Ahmad Yani Kota Metro Tahun 2019 dengan rata-rata 34 pasien perbulan, Sampel sejumlah 34 responden. Teknik sampling yang digunakan Accidental Sampling.Analisa data menggunakan analisa univariat dan analisa bivariat.

Hasil :Diketahui bahwa di RSUD Ahmad Yani Kota Metro Tahun 2019, sebagian perawat mempuyai komunikasi terapeutik tidak baik berjumlah 19 responden (55,9%), dansebagian besar pasien pre operasi mengalami kecemasan yang berjumlah 23 responden (67,6%).Berdasarkan hasil uji statistik, didapatkan p-value 0,007 atau p-value < nilai α (0,05) yang artinya terdapat hubungan antara komunikasi terapeutik terhadap kecemasan pasien pre operasi Di RSUD Ahmad Yani Kota Metro Tahun 2019 dengan nilai OR : 2,168.Diharapkan kepada pihak RSUD Ahmad Yani Kota Metro untuk dapat meningkatkan dalam memberikan pelatihan kepada seluruh tenaga keperawatan tentang komunikasi teraputik yang baik dan benar.
Studi tipe kepribadian millon dengan penyesuaian pernikahan pada pasangan dengan usia perkawinan diatas 10 tahun
Authors: Heryana Nur Rakhmanto , Ramadhan Muhammad Azhar
Published: September 2023

Background: Marriage sometimes does not always run smoothly, sometimes there are divisions. Therefore, it takes a good marital adjustment between partners. One of the factors in marital adjustment is to recognize the personality type of each partner. This personality type will affect the interaction in the couple it self.
Purpose: This paper aims to determine the effect of Millon's personality type on marital adjustment. The subjects were five married couples with a marriage age of over 10 years.
Methods:The technique used is a non-probability sampling technique, namely purposive sampling. The method for measuring marital adjustment uses the Dyadic Adjustment Scale (DAS), while the Millon Clinical Multiaxial Inventory-IV (MCMI-IV) is used to measure individual personality types. MCMI-IV is a measurement tool that can represent a person's personality type. Invalid MCMI-IV Guideline 1. Scale V > 1, 2. 3. Scale W > 19, Scale X < 7 and > 114, Scale 1-8B (All) < 60 (BR). In testing the research hypothesis using MCMI-IV and DAS software.
Result: The result is that there is an influence of personality type on marital adjustment.
Conclusion: Certain personality types correlate with patterns of marital adjustment between partners.
 
Keywords: Millon Personality; Personality Type; Marital Adjusment; Theodore Millon; Divoce Rate.
 
Pendahuluan: Perkawinan terkadang tidak selalu berjalan dengan lancar, terkadang terdapat perpecahan. Oleh karna itu dibutuhkan penyesuaian perkawinan yang baik antara pasangan. Salah satu faktor dalam penyesuaian perkawinan adalah mengenali tipe kepribadian pada masing-masing pasangan. Tipe Kepribadian ini akan mempengaruhi interaksi pada pasangan itu sendiri.
Tujuan: Untuk mengetahui pengaruh tipe kepribadian Millon terhadap penyesuaian perkawinan. Subjeknya adalah lima pasangan suami istri dengan usia pernikahan diatas 10 tahun. Teknik yang digunakan adalah teknik non-probability sampling, yaitu purposive sampling.
Metode: Metode untuk mengukur penyesuaian perkawinan menggunakan Dyadic Adjustment Scale (DAS), sedangkan untuk mengukur tipe kepribadian individu menggunakan Millon Clinical Multiaxial Inventory-IV (MCMI-IV). MCMI-IV merupakan alat ukur yang dapat merepresentasikan tipe kepribadian seseorang. Pedoman Tidak Valid MCMI-IV 1. Skala V > 1, 2. 3. Skala W > 19, Skala X < 7 dan > 114, Skala 1-8B (Semua) < 60 (BR). Dalam menguji hipotesis penelitian dengan menggunakan software MCMI-IV dan DAS.
Hasil: Terdapat pengaruh tipe kepribadian dengan penyesuaian perkawinan.
Simpulan: Tipe kepribadian tertentu berkorelasi dengan pola penyesuaian perkawinan antara pasangan.
Penggunaan koping pet attachment untuk mengatasi stress akademik pada mahasiswa
Authors: Imelisa Rahmi , Sarja Aurora Nur Ainun Syafira , Bolla Ibrahim Noch
Published: September 2023

Background: Most of the early adult age range, carry out their activities as a college students. As a student, a lot of stress occurs related to the learning process at college, this is known as academic stress. To overcome this, an appropriate coping mechanism is needed. Raising a pet (pet attachment) could be use as a coping strategy to deal with academic stress.
Purpose: This research aimed to determine the relation between pet attachment coping strategies and student academic stress at a college in Cimahi city.
Method: This study used a quantitative analytical survey method and cross-sectional design. Respondents were selected by purposive sampling technique as many as 89 students. Data analysis consisted of univariate analysis and bivariate analysis using the chi-square test.
Results: Based on data analysis, it was found that 53,9% of students had a moderate levels of academic stress, and 66,3% had a high attachment to pets. The bivariate test showed a p-value of 0,0006 (< α=0,05).
Conclusion:There is a relation between pet attachment coping strategies and academic stress in the college students.
Suggestion: It was suggested that the students use this coping strategies to cope with academic stress.
 
Keywords:  Stress; Academic; Student; Pets; Cross-Sectional.
 
Pendahuluan: Pada rentang usia dewasa awal, sebagian besar individu menjalani aktivitasnya sebagai seorang mahasiswa. Sebagai mahasiswa stress yang banyak terjadi berkaitan dengan proses pembelajaran di kampusnya, hal tersebut dikenal dengan istilah stress akademik. Untuk mengatasi hal tersebut, diperlukan mekanisme koping yang sesuai. Memelihara hewan peliharaan (pet attachment) dapat menjadi salah satu strategi koping untuk mengatasi stress akademik.
Tujuan: Penelitian ini bertujuan untuk mengetahui hubungan strategi koping kelekatan dengan hewan peliharaan(pet attachment)dengan stres akademik mah
asiswa di salah satu perguruan tinggi di Kota Cimahi.
Metode: Penelitian ini menggunakan metode kuantitatif survey analitik dengan rancangan cross sectional.Responden penelitian dipilih dengan teknik purposive samplingsebanyak 89 mahasiswa. Analisa data terdiri dari analisa univariat dan analisa bivariat menggunakan uji chi-square.
Hasil: Berdasarkan analisa data didapatkan 53,9% mahasiswa memiliki tingkat stres akademik sedang, dan 66,3% memiliki kelekatan hewan peliharaan yang tinggi. Uji bivariat menunjukkan hasil p-value sebesar 0,006 (< α=0.05).
Simpulan: Aada hubungan antara strategi koping pet attachment dengan stres akademik pada mahasiswa.
Saran: Diharapkan bagi mahasiswa untuk mengaplikasikan strategi koping ini untuk mengatasi stress akademik.
Financial Distress in Garment Company: During the Covid-19 Pandemic
Authors: Tyahya Tyahya , Ananta Yudha Luthfie , Ningrum Sekar Jati
Published: September 2023

Financial distress is characterized by a decline in the company's financial condition to the point of inability to meet its obligations. Financial distress is when a company faces financial difficulties that will lead to bankruptcy. Companies need to anticipate bankruptcy by measuring the level of financial distress using the Altman Z-Score method. This study aims to determine the results of financial distress predictions in the garment industry listed on the Indonesia Stock Exchange for 2018-2021 using the Z-Score model and to predict the financial distress conditions in the following year. This research uses a purposive sampling method by setting specific criteria to select samples, so six companies from 2018-2021 were taken as samples. Based on the data analysis, it can be concluded that there are five garment companies in the distress zone during the period 2018-2021 and 1 company in the grey zone in 2018 and 2019 but in 2020 and 2021 in the distress zone. The financial distress conditions for the next year in the garment products industry listed on the Indonesia Stock Exchange show that the company is in the distress zone.
The Effectiveness of Using Picture as Media Towards Students’ English Speaking Skills
Authors: Manurung Fitri Wahyuni , Sirait Dahlia
Published: September 2023

The objective of this research was to find out the effectiveness of using picture as media towards students' English speaking skills. This research was conducted at MAS Al-Manar Medan in the academic year 2022/2023. The samples of this research were 37 students of class XI IPA and IIS. This research was conducted using an experimental research design with two classes, the experimental class consisting of 19 students and the control class consisting of 18 students. The experimental group was given pre-test, treatment and post-test and the control group was given pre-test and post-test. The instrument of this research was an oral test, which was given in the pre-test and post-test. The results of this research showed that the t-observed value was higher than the t-table (15.288 > 2.030). The alternative hypothesis was accepted. It means that the effectiveness of using picture as media significantly affected towards students' English speaking skills.
Students’ Difficulties in Translating English Short Story into Indonesian at SMP Al-Ulum Terpadu Medan
Authors: Indah Arni Mutiara , Prawiyata Yugi Diraga
Published: September 2023

The study discussed the difficulties of the student in translating the short story from English into Indonesian. The purpose of this study was to know to what extent the students difficulty to translate the short story into Indonesian. The study Uses a Qualitative Descriptive Method. This instrument of study is students translation short story. The study is being conducted at the intermediate school the united Academic Year 2021-2022. The subject of the study taken by four high school students selected by research participants. The criteria of this study the students who had difficulty translating the shory story into Indonesian, The students translation. Students need to translate short stories so we know where their difficulty in translating the short story.
Brauchen wir ein Daten(wirtschafts)völkerstrafrecht?
Authors: Untch Christine , Wrobel Max
Published: September 2023

Die Macht des Stärkeren resultiert heutzutage nicht mehr nur aus physischer Stärke und Gewaltbereitschaft. Der „neue“ Faktor Daten verändert Machtstrukturen nachhaltig und unsichtbar. Datenmacht erfordert dabei Massenüberwachung, was nicht nur gegenwärtige Überwachungsskandale (etwa NSA oder Pegasus) sondern schon Unrechtsregime der Vergangenheit (NS-Deutschland, DDR) veranschaulichten. Das Strafrecht ist diesen Massenüberwachungen damals wie heute jedoch nicht entgegengetreten. Notwendig erscheint eine Debatte darüber, ob schwerwiegende systematische Datenschutz(menschenrechts)verletzungen durch Staat und Wirtschaft strafrechtlich erfasst sein sollten. Ende November 2022 luden daher Andreas Werkmeister und Julia Geneuss zu einem Symposium an der Humboldt-Universität zu Berlin, um Antworten auf die Tagungsfrage „Brauchen wir ein Daten(wirtschafts)völkerstrafrecht?“ zu finden.
Politischer Symbolismus oder Beitrag zur Heilung? Die Rolle von Entschuldigungen im Kontext sexualisierter Gewalt in Institutionen
Authors: Caspari Peter
Published: September 2023

Menschen, die (in ihrer Kindheit und Jugend) sexualisierte Gewalt erfahren haben, leiden häufig an Schuldgefühlen. Da Täterinnen und Täter in der Regel nicht glaubhaft um Entschuldigung bitten, sind Betroffene auf repräsentative und symbolische Formen der Entschuldigung angewiesen, um Anerkennung für das an ihnen begangene Unrecht und das erlittene Leid zu erfahren. In Deutschland wurden seit 2010 vielfältige institutionelle Strategien und Strukturen mit dem Ziel entwickelt, Betroffenen von sexualisierter Gewalt nachträglich Anerkennung und Unterstützung zukommen zu lassen. Der vorliegende Beitrag befasst sich mit Problemen und Grenzen solcher verspäteter »Wiedergutmachungsversuche« – aber auch mit der Frage, unter welchen Bedingungen die kollektive Bitte um Entschuldigung eine Chance besitzt, bei betroffenen Individuen auf Resonanz zu stoßen.
A genome‑wide approach to the systematic and comprehensive analysis of LIM gene family in sorghum (Sorghum bicolor L.)
Authors: Sarkar Md. Abdur Rauf , Sarkar Salim , Islam Md. Shohelul , Zohra Fatema Tuz , Rahman Shaikh Mizanur
Published: September 2023

The LIM domain-containing proteins are dominantly found in plants and play a significant role in various biological processes such as gene transcription as well as actin cytoskeletal organization. Nevertheless, genome-wide identification as well as functional analysis of the LIM gene family have not yet been reported in the economically important plant sorghum (Sorghum bicolor L.). Therefore, we conducted an in silico identification and characterization of LIM genes in S. bicolor genome using integrated bioinformatics approaches. Based on phylogenetic tree analysis and conserved domain, we identified five LIM genes in S. bicolor (SbLIM) genome corresponding to Arabidopsis LIM (AtLIM) genes. The conserved domain, motif as well as gene structure analyses of the SbLIM gene family showed the similarity within the SbLIM and AtLIM members. The gene ontology (GO) enrichment study revealed that the candidate LIM genes are directly involved in cytoskeletal organization and various other important biological as well as molecular pathways. Some important families of regulating transcription factors such as ERF, MYB, WRKY, NAC, bZIP, C2H2, Dof, and G2-like were detected by analyzing their interaction network with identified SbLIM genes. The cis-acting regulatory elements related to predicted SbLIM genes were identified as responsive to light, hormones, stress, and other functions. The present study will provide valuable useful information about LIM genes in sorghum which would pave the way for the future study of functional pathways of candidate SbLIM genes as well as their regulatory factors in wet-lab experiments.
Identification of druggable genes for multiple myeloma based on genomic information
Authors: Satria Rahmat Dani , Irham Lalu Muhammad , Adikusuma Wirawan , Puspitaningrum Anisa Nova , Afief Arief Rahman , Khair Riat El , Septama Abdi Wira
Published: September 2023

Multiple myeloma (MM) is a hematological malignancy. It is widely believed that genetic factors play a significant role in the development of MM, as investigated in numerous studies. However, the application of genomic information for clinical purposes, including diagnostic and prognostic biomarkers, remains largely confined to research. In this study, we utilized genetic information from the Genomic-Driven Clinical Implementation for Multiple Myeloma database, which is dedicated to clinical trial studies on MM. This genetic information was sourced from the genome-wide association studies catalog database. We prioritized genes with the potential to cause MM based on established annotations, as well as biological risk genes for MM, as potential drug target candidates. The DrugBank database was employed to identify drug candidates targeting these genes. Our research led to the discovery of 14 MM biological risk genes and the identification of 10 drugs that target three of these genes. Notably, only one of these 10 drugs, panobinostat, has been approved for use in MM. The two most promising genes, calcium signal-modulating cyclophilin ligand (CAMLG) and histone deacetylase 2 (HDAC2), were targeted by four drugs (cyclosporine, belinostat, vorinostat, and romidepsin), all of which have clinical evidence supporting their use in the treatment of MM. Interestingly, five of the 10 drugs have been approved for other indications than MM, but they may also be effective in treating MM. Therefore, this study aimed to clarify the genomic variants involved in the pathogenesis of MM and highlight the potential benefits of these genomic variants in drug discovery.
Structural dynamics insights into the M306L, M306V, and D1024N mutations in Mycobacterium tuberculosis inducing resistance to ethambutol
Authors: Maladan Yustinus , Safari Dodi , Parikesit Arli Aditya
Published: September 2023

Resistance to anti-tuberculosis drugs, especially ethambutol (EMB), has been widely reported worldwide. EMB resistance is caused by mutations in the embB gene, which encodes the arabinosyl transferase enzyme. This study aimed to detect mutations in the embB gene of Mycobacterium tuberculosis from Papua and to evaluate their impact on the effectiveness of EMB. We analyzed 20 samples of M. tuberculosis culture that had undergone whole-genome sequencing, of which 19 samples were of sufficient quality for further bioinformatics analysis. Mutation analysis was performed using TBProfiler, which identified M306L, M306V, D1024N, and E378A mutations. In sample TB035, the M306L mutation was present along with E378A. The binding affinity of EMB to arabinosyl transferase was calculated using AutoDock Vina. The molecular docking results revealed that all mutants demonstrated an increased binding affinity to EMB compared to the native protein (–0.948 kcal/mol). The presence of the M306L mutation, when coexisting with E378A, resulted in a slight increase in binding affinity compared to the M306L mutation alone. The molecular dynamics simulation results indicated that the M306L, M306L + E378A, M306V, and E378A mutants decreased protein stability. Conversely, the D1024N mutant exhibited stability comparable to the native protein. In conclusion, this study suggests that the M306L, M306L + E378A, M306V, and E378A mutations may contribute to EMB resistance, while the D1024N mutation may be consistent with continued susceptibility to EMB.
Whole genome sequence analyses of thermotolerant Bacillus sp. isolates from food
Authors: Sornchuer Phornphan , Saninjuk Kritsakorn , Tingpej Pholawat
Published: September 2023

The Bacillus cereus group, also known as B. cereus sensu lato (B. cereus s.l.), is composed of various Bacillus species, some of which can cause diarrheal or emetic food poisoning. Several emerging highly heat-resistant Bacillus species have been identified, these include B. thermoamylovorans, B. sporothermodurans, and B. cytotoxicus NVH 391-98. Herein, we performed whole genome analysis of two thermotolerant Bacillus sp. isolates, Bacillus sp. B48 and Bacillus sp. B140, from an omelet with acacia leaves and fried rice, respectively. Phylogenomic analysis suggested that Bacillus sp. B48 and Bacillus sp. B140 are closely related to B. cereus and B. thuringiensis, respectively. Whole genome alignment of Bacillus sp. B48, Bacillus sp. B140, mesophilic strain B. cereus ATCC14579, and thermophilic strain B. cytotoxicus NVH 391-98 using the Mauve program revealed the presence of numerous homologous regions including genes responsible for heat shock in the dnaK gene cluster. However, the presence of a DUF4253 domain-containing protein was observed only in the genome of B. cereus ATCC14579 while the intracellular protease PfpI family was present only in the chromosome of B. cytotoxicus NVH 391-98. In addition, prophage Clp protease-like proteins were found in the genomes of both Bacillus sp. B48 and Bacillus sp. B140 but not in the genome of B. cereus ATCC14579. The genomic profiles of Bacillus sp. isolates were identified by using whole genome analysis especially those relating to heat-responsive gene clusters. The findings presented in this study lay the foundations for subsequent studies to reveal further insights into the molecular mechanisms of Bacillus species in terms of heat resistance mechanisms.
The Effects of the G5 Educational Program on Treatment Adherence After Coronary Artery Bypass Graft Surgery
Authors: Saadati Fatemeh , Fotoukian Zahra , Jannat Alipour Zahra , Karimi Hengameh , Vafaey Hamidreza
Published: September 2023

Background: Patients undergoing coronary artery bypass graft (CABG) surgery have moderate to poor treatment adherence. These patients should benefit from simple, feedback-centered educational methods that produce deep and sustainable learning to improve their treatment adherence. Objectives: The present study was conducted to examine the effect of the G5 training program on treatment adherence in patients undergoing CABG. Methods: A quasi-experimental, pretest-posttest study was conducted on patients undergoing CABG visiting Rouhani Hospital, cardiology clinics, and cardiology physicians' offices in Babol, Iran. The participants were selected by convenience sampling, and those who met the study inclusion criteria were randomly assigned to an intervention (n = 37) or a control group (n = 37). Patients in the intervention group received a G5 training program (i.e., bags containing flashcards with questions and answers on lifestyle after surgery) and a 30-minute face-to-face, daily training session. The control group received 30 minutes of daily self-care instruction from a cardiac surgery nurse. A demographic and clinical data checklist and Modanloo's Adherence to Treatment Questionnaire (MATQ) were used to collect data before, one month, and two months after the intervention. Results: Most participants in the intervention and control groups were male (64.9% and 56.8%, respectively). The mean baseline treatment adherence score was 119.59 ± 7.82 in the intervention group, which changed to 152.62 ± 8.44 and 151.43 ± 8.65 one and two months after the intervention, respectively (P < 0.001). The mean baseline treatment adherence score was 120.35 ± 8.76 in the control group, which did not change significantly during the study (117.67 ± 6.28 and 116.97 ± 6.67 one and two months after the intervention, respectively). Repeated-measures analysis showed that the intervention significantly increased the mean treatment adherence score in the intervention group over time (P = 0.001). Female patients, patients with academic education, and urban patients scored higher on the query about the treatment, commitment to treatment, and sticking to treatment subscales, respectively. Conclusions: Education using the G5 method effectively improved treatment adherence of patients undergoing CABG. Nurses are suggested to follow up with patients, check their treatment adherence, and implement simple and low-cost educational methods, such as the G5 method, to improve patients' adherence to treatment.
The Association Between Peripheral Blood Neutrophil-to-Lymphocyte Ratio and Cirrhosis Complications in Adults with Compensated Liver Cirrhosis in Ahvaz, Iran
Authors: Hashemi Seyed Jalal , Shokrian Tosi Mohsen , Hajiani Eskandar , Parsi Abazar , Alavinejad Pezhman
Published: September 2023

Background: The neutrophil-to-lymphocyte ratio (NLR) is an inflammation biomarker in patients with liver cirrhosis. While increased NLR is linked to poor clinical outcomes and mortality in diseases like cancers, its association with cirrhosis complications has been sparsely examined. Objectives: This study aimed to evaluate the association between NLR and cirrhosis complications in patients with compensated liver cirrhosis. Methods: This retrospective cohort study was conducted on 256 patients with compensated liver cirrhosis visiting the Gastroenterology Clinic of Imam Khomeini Hospital, Ahvaz, Iran, in 2020. The peripheral blood lymphocyte and neutrophil counts were evaluated, and the NLR was calculated by dividing the absolute neutrophil count by the absolute lymphocyte count. Cirrhosis complications were assessed based on clinical and laboratory evaluation during 1 year of follow-up. Results: During the retrospective follow-up period, 59 patients (23.05%) experienced cirrhosis complications such as spontaneous bacterial peritonitis (n = 23), gastrointestinal bleeding (n = 22), and hepatic encephalopathy (n = 14). The baseline NLR, Model for End-Stage Liver Disease (MELD) score and Child-Pugh score were significantly higher in patients who later developed complications than in those who did not (P < 0.0001). The NLR with an optimal cut-off of > 1.95 had a sensitivity of 84.75% and specificity of 93.91% in predicting complications during the 1-year follow-up (AUC = 0.905, P < 0.0001). Conclusions: Our results indicated that the NLR is a simple, non-invasive, and cost-effective marker for predicting short-term complications in patients with compensated liver cirrhosis.