bluuebunny/crossref_metadata_2025 huggingface dataset:
Construction and Validation of a CRISPR/dCpf1-Based Transcriptional Regulatory System in Saccharomyces Cerevisiae
Authors: Feng Qing , Li Jun
Published: November 2023

Saccharomyces cerevisiae has been extensively studied and applied as a model microbial platform for efficient and sustainable production of biofuels, chemicals and natural products. In recent years, the application of CRISPR system in genome editing and transcriptional regulation has greatly improved the efficiency of microbial genome editing. To achieve transcriptional regulation the CRISPR/dCpf1-mediated CRISPRa/i transcriptional regulation system was constructed in this study. By constructing crRNA arrays and adding different activation proteins, repression efficiencies from 62% to 177% for the CRISPRi system and activation efficiencies from 154% to 320% for the CRISPRa system were achieved in the eGFP gene reporter system.
Retrosynthetic Analysis of the Synthetic Pathway for Antineocyclocitrinol A
Authors: Chen Sihan
Published: November 2023

With the discovery and exploration of deep-sea fungal metabolites, researchers have found that these abundant metabolites have a wide range of therapeutic effects on human diseases. Mutagenesis, purification and structural analysis of diverse deep-sea fungal metabolites have led to a new molecule named Antineocyclocitrinol A. This molecule is difficult to synthesize because it contains a complex structure such as the unusual bicyclo [4.4.1] A/B ring system with a bridgehead double bond. This paper explains an analytical strategy for retrosynthesis concretely and provides a theoretically feasible new synthetic pathway for synthesizing Antineocyclocitrinol A. This pathway fills a gap in the specific retrosynthetic analysis of Antineocyclocitrinol A and also serves as an application idea for a more detailed synthesis of cyclocitrinols analogs. Furthermore, this pathway promotes the development of the biopharmaceutical field by using deep-sea fungal metabolites.
Analyzing the territorial dimensions of work through a comparative study of waste recovery facilities in France and Brazil
Authors: Boudra Leïla , Souza Marcelo , Varella Cinthia , Béguin Pascal , Lima Francisco de Paula Antunes
Published: November 2023

BACKGROUND: Waste production and management from residents and collection for sorting are systems heavily dependent on territorial dimensions. Ergonomic research needs to better integrate such territorial determinants to improve work conditions and design sustainable work systems. OBJECTIVE: Through studies in France and Brazil, this paper analyzes the territorial relations that raise work systems’ sustainability challenges for materials recovery facilities (MRFs) and waste management in both countries and examines the links between work activity and territory in MRFs. METHODS: Both studies were based on the principles of activity-oriented ergonomics and used analyses of work activity and sociotechnical systems. The French study focused on interventions conducted over a 42-month period in five MRFs. The Brazilian study was based on a 20-month longitudinal qualitative and quantitative study. RESULTS: In this paper, we argue that territory is a key determining factor in waste production and work. Notably, the consumption patterns of residents and the economic flows within a geographic space determine the waste composition; and the territorially specified public policies, which define technical and social dimensions of waste collection and sorting. However, the territorial dimensions of waste are poorly considered in facility design. Workers’ health and sorting system performance are thus affected and negatively compromising plant performance. CONCLUSION: The territory appears as a blind spot in the design of work systems. One of the challenges is to create interfaces and devices that could help to integrate better human activity and waste territorialized anchorage, in a multilevel organization, from local communities to the global recycling chains.
Searching for a sustainable economy: Work, cooperation, and territorial solutions
Authors: Xavier Amanda Fernandes , Valle William Azalim do , de Souza Marcelo Alves , Duarte Francisco José de Castro Moura , Lima Francisco de Paula Antunes
Published: November 2023

BACKGROUND: This article discusses expanded governance of territorial issues as the basis for a sustainable way of producing and commercializing, as well as the relevance of work analysis within this governance. This discussion is developed from the Functionality and Cooperation Economy approach and from Brazilian experiences of organic food production and community-based solid waste management. OBJECTIVE: To identify and analyze the relationship between territorial issues and work activities in initiatives that seek territorial solutions for food and waste management in order to reflect on a sustainable economic transition and its challenges. METHODS: This article presents a reflection, a posteriori, concerning the follow-up of two initiatives that seek a sustainable economy and that, facing territorial issues, adopted different economic strategies. The field of research, by which the intended reflections are guided, originated from two intervention projects conducted by two different research/intervention groups. RESULTS: Our study highlights how the central focus on the effects of work in a territory can support the development of reflexivity and, consequently, the production of transversal cooperation and the sharing of material and immaterial resources, thereby leading to multifunctional territorial solutions. CONCLUSION: This study presents how the co-construction of multifunctional territorial solutions, involving cooperation among different actors, can be developed by an analysis of the respective activities involved. This analysis confers centrality to real work in order to feed the governance devices and enable the development of relationships of trust, necessary for living and producing in harmony, along with the construction of conventions and dynamic cooperation.
Gardening work in an urban environment and the notion of territory
Authors: Heddad Nadia , Biquand Sylvain
Published: November 2023

BACKGROUND: There are several characteristics of working in an urban environment that challenge the usual forms of work prescription. OBJECTIVE: This is a case study on the work of gardeners in an urban setting in the north of Paris. This paper develops the notion of territory, which we define as a system that is locally rooted in an open environment through the situated actions of gardeners’ work. As the employees do their work in an outside environment, interactions in real-life situations are beyond the control of work organization. City gardeners’ work is carried out in a green, living and human environment. METHODS: We conducted detailed open observations in a town’s green zones. These were complemented by individual interviews in work situations and by collective interviews within the boundaries of the municipality. RESULTS: We use the notion of territory to highlight the particularity of work within organizations where the work environment cannot be limited to the space inside their walls. The gardeners’ work makes it possible to link residents and passers-by (on foot or in vehicles) with the town’s green spaces (micro-ecosystems). Their work consists in connecting the different expectations and needs of the various life forms: the human beings (with a variety of lifestyles), as well as the plants, insects and animals. CONCLUSION: The particularities of working in an open environment create complex forms of prescription. The notion of territory, rarely used in ergonomics, proves to be fruitful for considering work in these contexts.
THE LEADER IN THE TECHNOLOGY AND EQUIPMENT DEVELOPMENT FOR THE ARC FURNACE STEELMAKING INDUSTRY AKONT LTD CELEBRATES 30 YEARS ANNIVERSARY
Authors: ZINUROV I. YU.
Published: November 2023

The Scientific and Technical Enterprise (STE) “Akont” celebrated its 30th anniversary in 2021. The information about the scientific and technical achievements of the staff of STE “Akont” is provided in this paper. According to the projects of STE “Akont” 18 ladle-furnaces for the out-of-furnace treatment of steel with capacity from 12 to 300 t have been produced and introduced in production for the last 30 years. It was noted that some of these units were designed according to non-standard scheme. The first Russian twin ladle-furnace facility LF-160-2 (AKP-160-2) developed by Akont was unique. The task of converting electric furnace DSP-100I6 installed in workshop ESPC-6 of Chelyabinsk Metallurgical Plant (ChMK) into a modern electric furnace with the bay window was successfully solved by Akont. In this case bath volume after the reconstruction increased to 145 t. Undoubtedly, the most outstanding achievement of Akont company was modernization of electric furnace No. 8 in workshop ESPC-2 of ChMK. As a result of the furnace modernization, the performance indicators improved drastically; the melting time decreased from 5.5 to 1 hour or less, the electric power consumption decreased from 560 to 334 kWh/t, the durability of the roof increased from 70 to 1500 melts and durability of the tubular panels reached 3000 melting operations. STE Akont Ltd has a number of new original propositions, including the design and technological development of the multifunctional MAGMA aggregate. This gasflame unit can be used for reduction of iron from converter and electric furnace slag and cast iron production. From slag with small additions of CaO and Al2O3 a clinker for cement industry may be obtained. The MAGMA process can be used for recycling of metal-containing radioactive waste from nuclear power plants.
Forensic Science and Forensic Expert Activity: a View Through the Prism of Forensic Experts’ Opinions
Authors: Shepitko Valery
Published: November 2023

The primary concerns of this paper are to study the phenomenon of forensic science and determine ways of optimizing forensic expert practice in Ukraine by summarizing opinions of forensic experts. Based on the survey conducted among forensic experts, issues of legal regulation of forensic science have been considered; the need to unify provisions governing conduct of forensic examination is justified; means of carrying out forensic expert activities (methods, methodologies, technologies) have been analyzed. Positions of forensic experts on certain procedural and substantive issues concerning appointment and conduct of forensic examinations have been determined. The role of the forensic expert’s automated workstation and electronic registers in forensic expert practice (the Register of Certified Forensic Experts and the Register of Methodologies of Forensic Examinations) is argued. The author underlines possibilities of improving the quality of forensic examination and outlines modern trends of international cooperation in the field of forensic science. The importance of cooperation between forensic science institutions of Ukraine within the European Network of Forensic Science Institutes is stressed. The Article Purpose is conditoned by the need to outline directions for forensic science development in Ukraine in current conditions and optimize forensic expert activity, as well as to determine ways to improve expert practice by summarizing forensic experts’ opinions. General scientific and special research methods have been used.
Epistemological Characteristic and Procedural Significance of Steps and Stages of Appointing and Conducting Forensic Veterinary Examination
Authors: Yatsenko Ivan
Published: November 2023

The Research Purpose is to single out epistemological characteristics of steps of appointing and conducting forensic veterinary examination and to reveal their procedural significance for pre-trial investigation and trial of cases concerning animals. It has been proven that these steps differ by subject, purpose, methods and include their own components: 1) preparation of materials and appointment of forensic veterinary examination (adopting a decision on forensic examination appointment; singling out forensic examination subject; defining forensic examination category according to procedural features; order of its performance, choosing time for its conduct; preparing source information; obtaining objects for subsequent research; selection of conducting subject; issuance of a procedural document on forensic examination appointment and the accused’s (suspect, defendant) familiarization with its content; determining expediency of the participants’ presence in the process while forensic examination; sending the procedural document on forensic examination appointment and research objects to the conducting subject; interaction between subjects involved in appointment and conduct of forensic examination); 2) carrying out research by a forensic expert using specific veterinary expertise; 3) research, evaluation and verification of the expert conclusion (seeking clarifications from a forensic expert or interrogating him/her in court; appointment of additional examination or re-examination (if needed); acquainting the parties with the expert conclusion). The research methodological basis is the systematic approach (general scientific and special scientific methods).
Relevance of Forensic Linguistic Speech Analysis in Criminal Cases Regarding Threat Incrimination
Authors: Kovkina Yevheniia , Aloyan Margarita , Avoyan Lilya
Published: November 2023

This article is devoted to specific issues of the linguistic semantic and textual speech analysis in criminal cases regarding incrimination of threats. Currently, forensic expert classifies the means of threats identified in the speech message (text) submitted for research at a pragmatic level. In contrast to purely semantic analysis of statements (when information is affirmative), pragmatic approach makes it possible to investigate the speech act as an expression of the will of a person, his emotions and feelings, determine the message illocutionary content, establish the addressee’s reaction to the information expressed by the addressee, etc. The article purpose is to determine the role of linguistic speech analysis in criminal cases regarding the threat incrimination. The objects of such forensic examination include the texts of text messages, e-mails, postcards, conversations (in particular, phone), audio and video messages, public speeches, etc. Illocutions of threats in statements where lexemes are used in direct meanings, and the sentences have a complete form according to the syntactic structure, are established on the basis of general semantic and textual research. Analyzing communicative situations in which incomplete or indirect statements are used, that means phrases expressed in an indirect form, where the illocution of a threat can be determined through speech intentions, communicative intentions, subjective-modal verbalizers, etc., is necessary. Forensic expert  conclusions based on the results of linguistic speech analysis of is one of the powerful means of making a court decision and an important argument during the pre-trial investigation in criminal cases regarding threat incrimination.
On Improvement of Scientific and Methodological Basis for Conducting Forensic Economic Examinations Considering Other Types of Forensic Examinations (review article)
Authors: Kapustnik Kostiantin , Khomutenko Olexiy , Kipouras Pavlos
Published: November 2023

Multidisciplinary forensic examinations reflect current tendency to integrate knowledge from various fields in order to objectively and impartially solve tasks of court proceedings, as integration of knowledge of specialists with different competences opens up new prospects for development of forensic examinations. Forensic economists who currently participate in multidisciplinary forensic examinations involving various kinds of interaction, sequence and degree of participation of each specialist in solving a common task have not been left behind. Article Purpose: to study into the need to develop scientific and methodological guidelines on the issues of carrying out forensic economic examinations while considering other types of forensic examinations. Leading methods of analysis and synthesis have been applied. The research paper substantiates the relevance of issues associated with conduct of forensic economic examinations taking account other types of forensic examinations. It is stressed that forensic economic examinations, during conduct of which results of other types of forensic examinations are used, do not fall under the concept of multidisciplinary forensic examination, since conclusions of other types of forensic examinations are not the research object of forensic economic examination. The paper emphasizes the need to develop an algorithm for conducting forensic economic examinations taking into account other types of forensic examinations. This will help forensic economists to use conclusions of other types of forensic examinations in multidisciplinary research without their evaluation, which in turn will enable to reduce the time for conducting forensic examinations and contribute to obtaining objective and unbiased expert conclusions.
Peculiarities of Conducting Forensic Merchandising Examination Related to Illegal Logging in Ukraine
Authors: Sivchuk Iryna
Published: November 2023

The research paper is dedicated to peculiarities of conducting forensic merchandising examination during investigation of crimes related to illegal logging in Ukraine. The negative impact of illegal logging on the environment is substantiated, and changes taking place in the territories of logging are stressed. On the contrary, logging related to forestry management is aimed at ensuring protection, rehabilitation, strengthening of protective properties and raising productivity of forests and other forestry lands. The Article Purpose is to theoretically substantiate peculiarities of perfomring forensic merchandising examination to determine the market value of round timber while investigation of crimes related to illegal logging, and to emphasize key aspects of conducting such research using the suggested algorithm of actions. The performed research is built on application of comparative approach involving the analysis of prices of sale and offers of this type of timber. The definition of the terms “timber”, “round timber”, their classification and characteristics are also provided. Merchandising research of round timber presupposes obtaining raw data on measurement of wood parameters and applying a certain algorithm of actions in order to assess their market value. The new national wood quality standards were analyzed and the need to attract a forest industry specialist in the course of forensic merchandising examination is justified.
Pengetahuan dan sikap ibu pada pemberian ASI esklusif di Puskesmas Tolo’ Jeneponto
Authors: Hijrawaty Rini Anriani , Ireine Tauran  , Rita Kombong  , Sylvianovelista R Losoiyo  , Faysal Kastella
Published: November 2023

Pemberian ASI eksklusif merupakan salah satu upaya untuk memperoleh tumbuh kembang bayi. ASI mengandung semua nutrisi penting dan mengandung zat antibodi untuk tumbuh kembang dan kekebalan tubuh bayi. Masih banyak ibu yang tidak memberikan ASI eksklusif dengan tepat pada bayinya, salah satu penyebabnya adalah kurangnya pengetahuan ibu tentang pemberian ASI eksklusif. Tujuan penelitian ini adalah untuk mengetahui hubungan tingkat pengetahuan dan sikap ibu dengan pemberian ASI eksklusif di wilayah kerja Puskesmas Tolo’ kabupaten Jeneponto. Penelitian survey analitik ini memakai rancangan cross sectional. Teknik total sampling digunakan dan didapatkan jumlah 45 orang. Instrumen yang digunakan dalam pengambilan data adalah kuesioner. Analisis data dilakukan dengan menggunakan Chi Square. Hasil penelitian didapatkan mayoritas responden berada pada rentang usia 19-40 tahun yakni sebanyak 32 orang (71,1%), berpendidikan SD yakni sebanyak 19 orang (42,2%), bekerja sebagai ibu rumah tangga (IRT) yakni sebanyak 36 orang (80%). Mayoritas responden memberikan ASI eksklusif yaitu 28 orang (62,2%), memiliki pengetahuan yang baik yaitu 28 orang (62,2%), serta memiliki sikap positif tentang pemberian ASI eksklusif sebanyak 24 orang (53,3%). Uji statistic disimpulkan terdapat hubungan tingkat pengetahuan ibu dengan pemberian ASI eksklusif x2 6,688 dan nilai p = 0,010, dan terdapat hubungan sikap ibu dengan pemberian ASI eksklusif diperoleh hasil x2 4,832 dan nilai p = 0,028.
Pemberian ASI eksklusif merupakan salah satu upaya untuk memperoleh tumbuh kembang bayi. ASI mengandung semua nutrisi penting dan mengandung zat antibodi untuk tumbuh kembang dan kekebalan tubuh bayi. Masih banyak ibu yang tidak memberikan ASI eksklusif dengan tepat pada bayinya, salah satu penyebabnya adalah kurangnya pengetahuan ibu tentang pemberian ASI eksklusif. Tujuan penelitian ini adalah untuk mengetahui hubungan tingkat pengetahuan dan sikap ibu dengan pemberian ASI eksklusif di wilayah kerja Puskesmas Tolo’ kabupaten Jeneponto. Penelitian survey analitik ini memakai rancangan cross sectional. Teknik total sampling digunakan dan didapatkan jumlah 45 orang. Instrumen yang digunakan dalam pengambilan data adalah kuesioner. Analisis data dilakukan dengan menggunakan Chi Square. Hasil penelitian didapatkan mayoritas responden berada pada rentang usia 19-40 tahun yakni sebanyak 32 orang (71,1%), berpendidikan SD yakni sebanyak 19 orang (42,2%), bekerja sebagai ibu rumah tangga (IRT) yakni sebanyak 36 orang (80%). Mayoritas responden memberikan ASI eksklusif yaitu 28 orang (62,2%), memiliki pengetahuan yang baik yaitu 28 orang (62,2%), serta memiliki sikap positif tentang pemberian ASI eksklusif sebanyak 24 orang (53,3%). Uji statistic disimpulkan terdapat hubungan tingkat pengetahuan ibu dengan pemberian ASI eksklusif x2 6,688 dan nilai p = 0,010, dan terdapat hubungan sikap ibu dengan pemberian ASI eksklusif diperoleh hasil x2 4,832 dan nilai p = 0,028.
USAHATANI PAKCOY SISTEM HIDROPONIK DALAM MENINGKATKAN PENDAPATAN PETANI
Authors: Rifqi Muhammad , Sasmi Meli , Mashadi Mashadi
Published: November 2023

Penelitian ini bertujuan untuk menganalisis biaya produksi, penerimaan, pendapatan, pendapatan kerja keluarga dan efisiensi usahatani pakcoy secara hidroponik milik Bapak Budianto di Kelurahan Simpang Tiga, Kecamatan Kuantan Tengah, Kabupaten Kuantan Singingi. Data dianalisis secara kuantitatif dengan menggunakan analisis pendapatan terhadap produksi, biaya dan harga pada sayuran pakcoy hidroponik dengan menggunakan program Microsoft Excel untuk menganalisis pendapatan dan tingkat efisiensi. Hasil analisis menunjukkan biaya penyusutan peralatan dalam satu kali proses produksi sebesar Rp 86.432,-, biaya tidak tetap Rp 559.263,- dan total biaya sebesar Rp 645.695,-, penerimaan sebesar Rp 715.000,-, pendapatan sebesar Rp 69.305,-, pendapatan kerja keluarga sebesar Rp 958.959 dan Nilai R/C sebesar 1,11 yang artinya setiap biaya yang dikeluarkan Rp 1,-, akan menghasilkan pendapatan kotor sebesar Rp 1,11,- atau pendapatan bersih sebesar Rp 0,11,-, dikarenakan nilai R/C lebih dari satu, maka dapat disimpulkan bahwa usahatani pakcoy hidroponik milik Bapak Budianto layak untuk dikembangkan.

The purpose of this study is to analyze production costs, receipts, income, family work income and the level of efficiency in Mr. Budianto's hydroponic pakcoy farming business in Simpang Tiga Village, Central Kuantan District, Kuantan Singingi Regency. The data were quantitatively analyzed using revenue analysis of production, costs and prices on hydroponic pakcoy vegetables using the Microsoft Excel program to analyze revenues and efficiency levels.The results of the analysis show that the cost of depreciation of equipment in one production process is IDR 86,432,-, non-fixed costs of IDR 559,263,- and the total cost of IDR 645,695,-, receipts of IDR 715,000,-, income of IDR 69,305,-, family work income of IDR 958,959 and R/C value of 1.11 which means that each cost incurred by IDR 1,-, will generate gross income of IDR 1.11,- or net income of Rp 0.11,-, because the R/C value is more than one, it can be concluded that Mr. Budianto's hydroponic pakcoy farming business is worthy of development.
The population of the Golden Horde time of the Eastern Black Sea region according to osteometry data (based on the materials of the excavations of the Natukhaevskoye 5 burial ground)
Authors:   Institute of Archaeology of the Russian Academy of Sciences, Dm.Ulyanova str., 19, Moscow, 117292, Russia, Petrova Kristina A.
Published: November 2023

Introduction. Osteometric data of adult individuals of the anthropological series from the burial ground of the Golden Horde time "Natukhaevskoe 5" are presented for the first time in this work. Based on the standard measurements, patterns of the skeletal constitution of the buried are discussed. As part of this study, we tested the hypothesis about the difference in the morphological appearance of two samples, combined according to the type of funeral rite - stone boxes and burial grounds. Materials and methods. The anthropological collection consists of the remains of 124 adult individuals, including 67 males and 57 females. Measurements of the postcranial skeleton were carried out according to the program of R. Martin (in version by V.P. Alekseev) according to 55 features. The degree of homogeneity of the male and female samples was determined using an intragroup analysis with the method of principal components for 10 features. The Mann-Whitney test was used to assess the statistical significance of differences. Results. The male population was rather tall with a shortened robust humerus and an elongated forearm bones, the lower limbs were long and massive. Among the female group, there is also a tendency to lengthen the lower limbs, relative to the upper ones, mainly due to the lower leg. The conducted intragroup analysis did not reveal statistically significant differences between the two groups, united according to the type of funeral rite, neither among men nor among women. However, a large range of linear size variations was found among men buried in stone boxes. Compared to them, the sample from the ground pit is more homogeneous. A different picture is observed in the female sample, where higher morphological diversity can be traced among those buried in the pits. @ 2023. This work is licensed under a CC BY 4.0 license
Analisis Motivasi Belajar Siswa Pada Mata Pelajaran Biologi di Sma Negeri 1 Luwuk
Authors: Anggo Sulasmi , Nurlia Nurlia , Marjuno Siti Aisyah , Laita Adeirma
Published: November 2023

Motivasi adalah keadaan psikologis yang berasal dari dalam diri seseorang mendorong untuk memunculkan perasaan senang serta kemauan yang kuat untuk melaksanakan suatu tindakan dalam meraih tujuan. Motivasi belajar siswa adalah dorongan yang menjadi dasar bagi siswa untuk ingin belajar dengan baik dan bersungguh-sungguh baik yang timbul dari dalam dirinya sendiri maupun dari luar. Penelitian ini bertujuan untuk mengetahui motivasi belajar siswa pada mata pelajaran biologi di SMA Negeri 1 Luwuk. Jenis penelitian yang digunakan yaitu penelitian deskriptif dengan pendekatan kualitatif. Penelitian dilakukan dengan membagikan angket kepada 215 responden yang diambil secara acak dari 562 populasi. Hasil penelitian ini menunjukkan bahwa 0,93% siswa tergolong motivasi sangat rendah, 14,90% siswa tergolong motivasi rendah, 61,40% siswa tergolong motivasi tinggi dan 22,80% siswa tergolong motivasi sangat tinggi. Sehingga pada umumnya motivasi belajar siswa pada mata pelajaran biologi di SMA Negeri 1 Luwuk berada pada kategori sangat tinggi.
The Influence of Internal and External Factors on Financial Performance in Enhancing the Competitiveness of Small and Medium Enterprises in Papua
Authors:   University of Science and Technology Jayapura, Mugiati Mugiati , Wadjo Muhammad Amin ,   University of Science and Technology Jayapura, Aditama Muhammad Irfan ,   University of Science and Technology Jayapura
Published: November 2023

This study aims to identify and analyze the direct influence of internal factors, which consist of Human Resource Management, Production, Marketing, Working Capital, and Organizational aspects, as well as external factors, including Government Policies and Financial Performance, on Small and Medium Enterprises' competitiveness in Papua. Data was collected through observations, interviews, and questionnaires. The data was analyzed using Structural Equation Modeling (SEM) with Amos Software. The analysis results indicate that human resource management does not significantly affect the financial performance of Small and Medium Enterprises in Papua, whereas production, marketing, working capital, and organizational factors do influence financial performance. The analysis also shows that these internal factors impact the competitiveness of Small and Medium Enterprises in Papua. Furthermore, external factors, such as government policies and competition, affect both the financial performance and competitiveness of small and medium enterprises in Papua. Additionally, financial performance is found to be linked to the competitiveness of Small and Medium Enterprises in Papua.
The Effect of Trust in Government and Perceptions of Tax Justice on Tax Compliance with Job Type as Moderation (Empirical Study on Individual Taxpayers Registered at Jayapura Primary Tax Service Office)
Authors:   Cenderawasih University, Tuhumena Ruland , Falah Syaikhul ,   Cenderawasih University, Salle Hesty T. ,   Cenderawasih University
Published: November 2023

This study aims to analyze and provide empirical evidence of the effect of trust in government and perceptions of tax justice on tax compliance with job type as moderation at the Jayapura Primary Tax Service Office. The study's population consists of all Individual Taxpayers (WPOP) who are registered at KPP Pratama Jayapura, with a total population of 283,000 taxpayers. The study's sample comprised 100 respondents who were taxpayers. The researchers employed a non-probability sampling method, specifically convenience sampling techniques. The data gathering process involved the distribution of questionnaires to the respondents. The acquired data was then subjected to analysis using the Structural Equation Model (SEM) technique, employing the Partial Least Square (PLS) method within the WarpPLS 7.0 program. The test results of this study indicate that (1) trust in government has a positive and significant effect on tax compliance; (2) perceptions of tax justice have a positive and significant effect on tax compliance; (3) job type has not been able to moderate the effect of trust in government on tax compliance; and (4) job type has not been able to moderate the effect of perceptions of tax justice on tax compliance.
Functional nutrition for vascular and metabolic health in clinical practice
Authors:   Korean Institute for Functional Medicine, Park Byoungjin
Published: November 2023

Blood pressure, blood sugar, and lipid health are easily overlooked in their twenties or thirties. Still, if blood pressure is high in the normal range or metabolic abnormalities persist, microstructure damage could accumulate little by little in all organs receiving blood supply, with changes in vascular endothelial cells. Daily vascular health care can be very important for overall health throughout life, and cardiometabolic health management is necessary for anyone, whether early or late. Understanding and utilizing clinical nutrition via functional medicine can also be an essential starting point for cardiovascular and metabolic health management. Furthermore, harmonious management through functional medicine's care and conventional medicine's control can have additional health benefits from a preventive perspective.
Treatment of androgen deficiency syndrome and functional approach
Authors:   Korean Institute for Functional Medicine, Kim Young-Sang
Published: November 2023

Male hypogonadism, also known as androgen deficiency syndrome, refers to age-related alterations in hormone levels and the consequent symptoms observed in middle-aged and elderly men. Testosterone, a crucial male sex hormone, plays a central role in androgen deficiency syndrome. This review aims to investigate the intricate connection between testosterone deficiency and male health. Additionally, we delve into the potential benefits of testosterone replacement therapy in enhancing metabolic function. Furthermore, we explore lifestyle habits and functional strategies for promoting intrinsic testosterone levels.
Two cases of histamine syndrome with food intolerance and adrenal fatigue
Authors:   Korean Institute for Functional Medicine, Lee Sang-Hoon , Kim Sang Man
Published: November 2023

Histamine is known as a substance that causes allergies and anaphylaxis, but, in fact, it is a kind of inflammatory cytokine which is involved in immune and inflammatory responses that protect from external materials, such as dust, parasites, and bacteria. Histamine mainly plays a role in physically washing or sterilizing these substances through vasodilation, increasing mucus secretion and expectoration, smooth muscle contraction, and gastric acid secretion. In addition, histamine has central nervous system effects such as arousal and memory, because it is necessary to remember and avoid harmful exposures. Like other cytokines, histamine must be produced, released, and degraded in a balance for proper action. When this balance is broken, various non-specific symptoms from histamine excess, such as rhinitis, urticarial, itching sense, abdominal cramp, diarrhea, epigastric burning, chronic cough, headache, dizziness, edema, insomnia, nervousness, and irritability can be appeared. It is defined as “histamine imbalance” in functional medicine, and some researchers are called it as “histamine syndrome”. This complexity of symptoms often complicates accurate diagnosis, leading to partial or symptomatic treatments. Consequently, histamine syndrome can escalate healthcare burden and decrease quality of life. An integrative and functional medicine approach is important due to this situation. Moreover, histamine syndrome often coexists with food intolerance and adrenal fatigue (functional adrenal insufficiency), necessitating a comprehensive approach that addresses all these aspects simultaneously. In this report, we present two cases of patients with histamine syndrome, accompanied by food intolerance and adrenal fatigue, to explore appropriate directions for functional medicine diagnosis and treatment strategies.
Does COVID-19 stress affect the individual work performance (IWP) of health workers in hospitals during the pandemic?
Authors: Zamralita  , Hermawan Aurelio , Basaria Debora
Published: November 2023

Health workers are at the frontline risk of contracting the COVID-19 virus. This study aims to determine the effect of COVID-19 stress on individual work performance in health workers in hospitals during the pandemic. The measuring tool used is the COVID Stress Scale and Individual Work Performance Questionnaire/ This study uses a quantitative descriptive method. The participants in this study were 220 health workers. The results showed that there was an effect of COVID-19 stress on individual work performance in health workers during a pandemic with a significance level (Sig) .000< .05. From the results of coefficient determination (R Square), a contribution is .368 obtained.
The Effect of Hustle Culture on Job Satisfaction Among Startup Workers in Indonesia
Authors: Aziz Khalida Salsabila , Abdhy Aulia Adnans
Published: November 2023

This research aims to acknowledge the hustle culture's effect on startup workers' job satisfaction in Indonesia. The research method used in this research is descriptive quantitative with a purposive sampling method. The sample of this research is 351 subjects. Data collection uses Likert scales, namely JDI (Job Descriptive Index) and Hustle Culture Scale. The method of data analysis is a simple regression analysis method. Results from the research showed a negative effect of hustle culture on job satisfaction with a negative direction of the effect. The result concluded that the higher the hustle culture, the lower the job satisfaction.
THEORETICAL PRINCIPLES OF ENTERPRISE COMPETITIVENESS MANAGEMENT IN THE CONTEXT OF THE SYSTEMS APPROACH
Authors:   Yuriy Fedkovych Chernivtsi National University, Verbivska Liudmyla
Published: November 2023

The article examines the issue of the formation of the enterprise competitiveness management system in the context of a systemic approach. The purpose of the article is to develop theoretical provisions for the formation of the enterprise competitiveness management system. To achieve the goal,the general scientific methods of knowledge of phenomena and processes have been used, such as: methods of induction and deduction – to clarify the relationship between the components of the enterprise's competitiveness management system; methods of system analysis and generalization for systematization of existing scientific approaches, used theoretical sources and scientific literature; structuring method – to distinguish the stages of implementation of the complex mechanism to manage the competitiveness of the enterprise; the method of abstraction and formalization – for the development of the conceptual foundations of the competitiveness management system; the graphic method – for displaying the theoretical and methodological material of the research. The purpose and tasks of the enterprise competitiveness management system have been defined. The main components of the modern concept of enterprise competitiveness management have been highlighted. It has been substantiated that the construction of enterprise competitiveness management processes on the basis of a systemic approach will contribute to the formation and development of sustainable competitive advantages of the enterprise under the conditions of adaptation to the influence of an environment with a high degree of variability and uncertainty. The system of enterprise competitiveness management principles based on a systemic approach has been proposed. It has been determined that the implementation of a systemic approach to the management of the enterprise's competitiveness is possible on the basis of the development of an appropriate complex mechanism. It has been based on the technological, economic, economic, social, and marketing components of the enterprise's functioning. The stages of implementation of the competitiveness management mechanism has been proposed, which have a target of adaptation to changes in the market environment and competitive potential of the enterprise, ensuring the support of its market position.
STRATEGY AND TACTICS OF BUSINESS COLLABORATION: CLUSTERING AND OTHER JOINT ACTIVITIES
Authors:   Odesa National Maritime University, Kovalenko Mykola , Belous Kateryna ,   Odesa National Maritime University, Krysyuk Larysa ,   Odesa National Maritime University
Published: November 2023

Collaboration (or cooperation) between business entities is an essential element of business strategy and tactics, as the synergistic effects synthesized by this phenomenon can manifest themselves in increased competitiveness of business entities, the development of their innovation, the reduction of operational risks, and in other areas. The above provisions emphasize the overall significance of research on the strategy and tactics of collaboration among business entities. Therefore, the purpose of the article is to identify the characteristics of forming a strategy and tactics for collaboration among business entities through clustering and other forms of joint activities. Based on the study of the characteristics of forming the strategy and tactics of collaboration among business entities, particularly in the form of clusters and other joint activities, several conclusions have been drawn. It has been noted that while collaboration among business entities can take various forms, the format of the strategy and tactics of collaboration among business entities remains unchanged. It has been demonstrated that there are classical elements of collaboration strategy and tactics, which include: the circle of collaboration participants, the format of goals and objectives, the format of strategy, the format of tactical actions, the format of resource allocation and responsibilities, the format of monitoring and evaluation, the format of communication and interaction, and the format of analysis and correction of collaboration strategy and tactics. Each of the outlined elements, while having a common essence, takes on individual content that depends on the form of collaboration. It has been observed that the better the classical elements of strategy and tactics align with the form of collaboration, the greater the mutual benefit and synergy. Under these conditions, collaboration allows participants in joint activities to achieve maximum mutual benefit and a synergistic effect that exceeds individual achievements. For example, in clusters, various business entities can jointly utilize resources and knowledge for the collaborative development of innovative products. The research results allow for an exploration of the Ukrainian context of business entity collaboration in the direction of clustering and other joint activities.
РОЛЬ ІНВЕСТИЦІЙНО-ІННОВАЦІЙНОЇ СКЛАДОВОЇ В СИСТЕМІ ЗАБЕЗПЕЧЕННЯ СТАЛОГО ЕКОНОМІЧНОГО РОЗВИТКУ УКРАЇНИ: ТЕОРЕТИЧНІ ЗАСАДИ ТА ПРАКТИЧНІ РЕКОМЕНДАЦІЇ
Authors: Атамас О.П.
Published: November 2023

У статті розкрито теоретичні засади трактування економічної дефініції «інвестиційно-інноваційна складова» в системі забезпечення сталого економічного розвитку України, проаналізовано головні категорії теоретичних підходів до трактування дефініції «інвестиційно-інноваційна складова», надано характеристику стану економіки держави з метою проведення оцінки та аналізу її «інвестиційно-інноваційної складової» в системі забезпечення сталого економічного розвитку. Безумовно, з огляду на сучасні трансформаційні зміни економічних систем та коливання сектору інвестиційного забезпечення, - роль інвестиційно-інноваційної складової в системі забезпечення сталого економічного розвитку України як у контексті теоретичних аспектів, так і з позиції надання практичних рекомендацій важко переоцінити. У статті проаналізовано значення економічної категорії «стратегія» крізь призму формування стратегічного плану економічного розвитку України, надане розширене обґрунтоване трактування означеної економічної дефініції. У матеріалах наукового дослідження акцентується окрема увага на ролі інвестиційно-інноваційної складової в системі забезпечення сталого економічного розвитку держави крізь призму визначення рівня її інвестиційної привабливості на світовій арені, з урахуванням глобалізаційних зрушень, трансформаційних перетворень, діджиталізації та трансферу технологій. Крім того, у науковому дослідженні визначено основні фактори забезпечення високого рівня інвестиційної привабливості економіки держави з метою її інноваційного розвитку та модернізації в системі забезпечення сталого економічного розвитку. Таким чином, при проведенні комплексного наукового дослідження у означеній тематиці приділено особливу увагу не лише внутрішнім складовим елементам сталого економічного розвитку України, а й проаналізовано комплексне значення зовнішніх факторів економічного впливу, рейтингових оцінок та аналізу рейтингових міжнародних агентств. Основними методами дослідження, що застосовувались при викладенні наукового матеріалу, стали загальноекономічні та спеціальні наукові методи, метод аналізу, статистичний метод.
HUBUNGAN ANAK DENGAN ORANG TUA DI DALAM KITAB PERHIASAN BAGUS MENURUT NASKAH UTSMAN BIN ABDULLAH BIN ‘AQIL BIN YAHYA AL-‘ALAWI
Authors: Sakinah Milya , Annisa Virginia , Saputra Riwan
Published: November 2023

Abstract: The relationship between children and their parents is very important as explained in the book of good jewelry, we as children must be obedient or dutiful to our parents, but nowadays there are many children who disobey their parents, such as arguing, hitting and even killing their parents. they. This research will examine the importance of filial piety to parents and children's obligations to parents in the book on fine jewelry as well as bk science and other sciences.

Keywords: Relationship, Devotion to parents, obligation Disobedience. Uthman bin Abdullah's fine jewelry

 

Abstract: Hubungan anak dengan orang tua sangat penting sebagaimana dijelaskan dalam kitab perhiasan bagus ,kita sebagai seorang anak harus taat atau berbakti kepada orang tua,tetapi pada zaman sekarang banyak anak-anak yang durhaka kepada orang tua seperrti membantah,memukul bahkan sampai membunuh orang tua mereka. Penelitian ini akan mengkaji mengenai penting berbakti kepada orang tua dan kewajiban anak kepada orang tua dalam kitab perhiasan bagus serta ilmu bk dan ilmu-ilmu lainnya.

Kata kunci: Hubungan,Berbakti kepada orang tua, kewajiban, Durhaka, Perhiasan bagus, Utsman bin Abdullah
UNSUR KOMUNIKASI PADA PROSES PEMBELAJARAN DI TAMAN KANAK-KANAK (TK) TUNAS JAYA DESA JELUTUNG KECAMATAN SUNGAILIAT KABUPATEN BANGKA
Authors: Hidayati Yuli Hidayati
Published: November 2023

This research discusses the elements of communication in the learning process at Tunas Jaya Sungailiat Kindergarten (TK) in Bangka. The theory used is based on the elements of communication according to Lasswell, which consist of communicator, message, communicant, media, and effect. The research design employed is descriptive with a qualitative approach. Data collection techniques include observation, interviews, and documentation. The research findings indicate that the elements of communication in the learning process at TK Tunas Jaya have been executed effectively. These elements include: Communicator, represented by the teachers at TK Tunas Jaya in the Sungailiat Sub-district, Bangka Regency. Message, conveyed by teachers in both verbal and non-verbal forms. Communicant, involving TK students and their parents. Media, utilizing smartphones supporting the WhatsApp application, enabling communication in groups. Effect, resulting in increased activity among children in the learning process. Based on these findings, it is suggested to improving their communication skills to effectively convey messages to children. Teachers are also encouraged to introduce other innovations in the learning process, ensuring that all early childhood students with diverse characteristics can quickly grasp the learning material.
STUDI EKSPLORASI POLA KOMUNIKASI PEMBELAJARAN BERBASIS VIRTUAL
Authors: Saiful Anwar , Hasanah Uswatun , Musa Musa
Published: November 2023

Improvements in communication technology have a broad impact in various fields, including education. The pattern of learning communication has changed from face-to-face learning activities to virtual-based learning. This virtual-based communication pattern is getting stronger with the presence of the Covid-19 pandemic. This research aims to eksplore various articles related to virtual-based learning communication patterns. This research uses the Systematic Literature Review (SLR) method with meta-synthesis analysis techniques. Data collection in this study was carried out by collecting articles from 2020-2023 that have a similar focus. The articles analyzed in this study were 9 accredited national journal articles obtained from the Google Scholar database using Harzing's Publish or Perish application with the keyword virtual-based learning communication patterns. This study found that the virtual learning process can run well, not only supported by mastery of the application used but also supported by the involvement of parents as a substitute for the teacher's role in the learning process as a facilitator, motivator, and director.