bluuebunny/crossref_metadata_2025 huggingface dataset:
The Risk of Crimean Congo Haemorrhagic Fever in India as a Growing
Health Concern
Authors: Garg Gurisha , Garg Sonakshi , Kamal Raj , Kurmi Balak Das , Singh Amandeep
Published: March 2024

Every year witnesses an outbreak of some or the other zoonotic disease that causes the
unparalled loss of human life. The year 2022 presented the outbreak of Crimean Congo haemorrhagic fever (CCHF), which brought unprecedented challenges to individuals as well as to the
healthcare system all around the world, making it a serious health concern. Rising health concerns
have highlighted the importance of managing and decreasing the further transmission of the
CCHF virus. CCHF is one of tick-borne viral diseases, which spreads due to various reasons like
changes in global warming, environmental influences, and other ecological factors. All these factors somehow impact the disease prevalence. This disease has a negative impact on both humans
and livestock. The diverse climate and significant livestock population of India make it susceptible to the prevalence of CCHF. Therefore, it is the need of the hour to develop some strategies in
order to tackle the challenges posed by CCHF. This article includes all the cases of CCHF that
have occurred in India from the year 2011, along with the fatality rates associated with this disease. Also this study discusses the need to explore some specific drugs for the management and
prevention of such diseases. In addition, the pathogenesis of the disease progression, along with
some protective measures suggested by the government has been described for prevention of
CCHF. Subsequently, this article attempted to draw attention towards the risk that may be posed
by CCHF in the coming scenario, emphasizing the importance of taking proactive measures in
anticipation of such risks.
Cutting Finite Element Simulation of Quenched Steel GCr15 Based on
ABAQUS
Authors: Yang Lin , Gong Junhao , Liu Jialiang , Xia Jianqiu , Zhang Yu
Published: March 2024

Background:

The substantial cutting force and elevated cutting temperature during the
machining of hardened steel GCr15 exacerbate tool wear.

Objective:

In this study, the influence of cutting parameters on cutting force and cutting temperature
in the process of hard-cutting GCr15 was studied, the cutting parameters were optimized, and
the cutting force and cutting temperature were predicted.

Methods:

The cutting simulation model was constructed using ABAQUS software, and the cutting
force and cutting temperature were investigated under various cutting parameters through range
analysis, variance analysis, and signal-to-noise ratio transformation analysis.

Results:

The simulation and experimental results demonstrated that the cutting force could be optimized
by utilizing cutting speed vc=140 m/min, feed rate f=0.1 mm/r, and cutting depth ap=0.1
mm. Under these conditions, the cutting force in the x-direction was measured as 78.560N, while
the cutting force in the y-direction was 32.423N. Moreover, for achieving the optimal cutting temperature,
the recommended cutting parameters were cutting speed vc=120 m/min, feed rate f=0.1
mm/r, and cutting depth ap=0.4 mm.

Conclusion:

Compared to the conventional analytical method, which is burdened with high costs
and low efficiency, the patent leverages finite element simulation technology to replicate the hardcutting
process and its underlying cutting mechanism. This innovation simplifies the otherwise
complex and laborious experimental and measurement procedures. By studying cutting force and
cutting temperature, the optimization of cutting parameters can be achieved, thus offering valuable
theoretical insights for practical production.
Management strategy and research productivity in the Peruvian Institute of Nuclear Energy for the period 2000 – 2020
Authors: Montoya Zavaleta Modesto Edilberto , Figueroa Donayre Edgardo Martin , Mantari Laureano Jose Luis
Published: March 2024

This paper analyzes the production indicators for the period 2000-2020 of the Peruvian Institute of Nuclear Energy, an institution that researches and applies knowledge of ionizing radiation. The research institute published an average of one article per year between 1984 and 2000. During the period 2001 to 2006, some policies were applied. Staff salaries were tripled, allowing the incorporation of researchers with experience in scientific research. The number of publications increased from 01 in 2001 to 15 in 2007 as a result of intense work done in 2006. These policies were ignored in 2007 with a significant change in research productivity in years to come. Finally, an overall analysis determines that: (a) management actions are different from manager director to manager director and the changes substantially affect research productivity, (b) the policy that increases researcher salary may be more detrimental than reducing the total annual budget for research since by increasing the researcher salary is still possible to preserve research indicator trends.
Engineering Economic Systems: Past, Present and Future
Authors: Brandeau Margaret
Published: March 2024

At Stanford, engineering economic systems emerged as a discipline in the late 1960’s. The department’s curriculum had four central areas: decision analysis, optimization, economic sciences, and dynamic systems. The emphasis was on both practice and theory. The Management Science and Engineering Department at Stanford (MS&E), founded in 2000, is an outgrowth of the former Engineering Economic Systems Department. MS&E focuses on the codesign of engineering platforms and social systems in the 21st century, at scale and with pervasive data. The goal is to understand, design, implement, and control large-scale, integrated systems of people and machines. The intellectual spectrum ranges from analytics and computation to social and behavioral sciences. This article describes examples of past and present projects in the areas of energy, education, the economy, the environment, and health. Looking to the future, we are likely to see the continual emergence of new technologies, increasing amounts of data, increasing levels of connectivity, advances in computing, ubiquity of machine learning and artificial intelligence, and increasing importance of the need to address social and environmental problems. These will lead to new ways of analyzing problems and rich new opportunities for the tools of engineering economic systems to have impact.
Alberto Chirif: "Es necesario garantizar una gestión integral de los pueblos indígenas y de sus territorios ancestrales"
Authors: Santos Cajahuanca Joyce Hyllarie
Published: March 2024

El antropólogo peruano Mg. Alberto Chirif, nacido en Lima, ha dedicado más de 45 años a la investigación de los pueblos amazónicos. Es cofundador del Centro de Investigación y Promoción Amazónica (CIPA) y ha dirigido el programa de desarrollo y conservación Pacaya Samiria durante dos años y medio, financiado por el Fondo Mundial para la Naturaleza (WWF) de Dinamarca.
Desde su residencia en Iquitos, ha producido una serie de obras que han permitido comprender la problemática, cosmovisión y aspiraciones en los pueblos amazónicos, así como reflexionar sobre su futuro. Su trabajo ha evolucionado hacia el enfoque en los derechos colectivos de los pueblos indígenas.
Ha sido autor de obras destacadas como "Después del caucho" (2018) y "Pueblos indígenas amazónicos e industrias extractivas" (2011). Además, ha ejercido como editor en obras como "Etnicidad y ecología" (1979), "Deforestación en tiempos de cambio climático" (2018) y "Una historia para el futuro: territorios y pueblos indígenas en Alto Amazonas" (2002).
Effect of Caring Behaviour: A Study Protocol of Caring-based Education Program
Authors: Ishak Siti Aishah , Ahmad Sharoni Siti Khuzaimah , Seman Nordianna , Septa Katmawanti
Published: March 2024

Caring behaviour is essential and crucial to nursing, and it has become an important component in providing appropriate nursing care to patients. This study aims to determine the effect(s) of a caring-based education program on critical care nurses' caring behaviour, efficacy, and work environment. This study will employ a quasi-experimental design with two groups: control (n = 40) and intervention (n = 40) from critical care settings in Penang public hospitals. The data will be analyzed using descriptive and inferential analysis; Pearson correlation coefficient, independent t-test, analysis of variance (ANOVA), and paired t-test.
Corpoica Dorada :variedad de uchuva para Boyacá, Cundinamarca y Antioquia
Authors: Sánchez Betancourt Erika Patricia , Mayorga Cubillos Franklin Giovanny , Navas Arboleda Alejandro Alberto , Gómez Gil Luis Fernando , Núñez Zarantes Víctor Manuel
Published: March 2024

La Corporación Colombiana de Investigación Agropecuaria (Corpoica), cumpliendo con su misión de obtener oferta varietal para las zonas productoras en las que se encuentran pequeños, medianos y grandes productores de uchuva, hace entrega de la variedad de Corpoica Dorada, para las condiciones de cultivo de Antioquia y Boyacá-Cundinamarca. Esta variedad corresponde a una de las tres primeras inscritas en el Registro Nacional de Cultivares del ICA y la primera variedad generada en laboratorio por cultivo in vitro de polen
Examining developmental diversity in early infancy: multilevel factors in a Japanese birth cohort study (Preprint)
Authors: Kato Daigo , Okuno Akiko , Ishikawa Tetsuo , Itakura Shoji , Oguchi Shinji , Kasahara Yoshiyuki , Kanenishi Kenji , Kitadai Yuzo , Kimura Yoshitaka , Shimojo Naoki , Nakahara Kazushige , Hanai Akiko , Hamada Hiromichi , Mogami Haruta , Morokuma Seiichi , Sakurada Kazuhiro , Konishi Yukuo , Kawakami Eiryo
Published: March 2024

BACKGROUND

Developmental diversity (DD) challenges traditional disorder classifications that view neurodevelopmental differences as determined by human variations. However, few studies have longitudinally examined DD and the coordinated effects of child and maternal factors on DD.

OBJECTIVE

The purpose of this study is to reveal how DD arises by longitudinally examining child/maternal factors from the perinatal period through infancy.

METHODS

A prospective longitudinal observational study including 147 mothers and their children was conducted; data from gestation to 12 months postpartum were obtained. Assessments were performed during prenatal visits (questionnaires and blood collection); delivery (cord blood); and postpartum visits at 1, 6, and 12 months (questionnaires). The Modified Checklist for Autism in Toddlers (M-CHAT) was used to evaluate individual developmental characteristics (IDC). The relationship between the M-CHAT score and other longitudinal variables was assessed using polychoric or polyserial correlation coefficients. L2-regularized logistic regression and SHapley Additive exPlanations (SHAP) were used to predict the M-CHAT score and to determine each feature’s contribution.

RESULTS

A total of 21 factors (4 prenatal, 3 at birth, and 14 postnatal) showed significant statistical associations with the M-CHAT score (adjusted P-values < .05). The predictive accuracy for the M-CHAT score was satisfactory (area under the receiver operating characteristic curve = .79). Infant sleep status after 6 months of age (nighttime sleep duration, bedtime, and difficulties falling asleep), as well as maternal Kessler Psychological Distress Scale (K6) and Mother-to-Infant Bonding Scale (MIBS) scores after the late gestation, were important predictors.

CONCLUSIONS

Maternal K6 scores, MIBS scores, and poor infant sleep status were predictors of IDC. This study advances the understanding of DD in clinical research.

CLINICALTRIAL

The study was registered in a clinical trial registry (UMIN000034837, registered on November 9, 2018) before commencement.
Regulating AI in Mental Health: Ethics of Care Perspective (Preprint)
Authors: Tavory Tamar
Published: March 2024

UNSTRUCTURED

This article contends that the responsible artificial intelligence (AI) approach—which is the dominant ethics approach ruling most regulatory and ethical guidance—falls short because it overlooks the impact of AI on human relationships. Focusing only on responsible AI principles reinforces a narrow concept of accountability and responsibility of companies developing AI. This article proposes that applying the ethics of care approach to AI regulation can offer a more comprehensive regulatory and ethical framework that addresses AI’s impact on human relationships. This dual approach is essential for the effective regulation of AI in the domain of mental health care. The article delves into the emergence of the new “therapeutic” area facilitated by AI-based bots, which operate without a therapist. The article highlights the difficulties involved, mainly the absence of a defined duty of care toward users, and shows how implementing ethics of care can establish clear responsibilities for developers. It also sheds light on the potential for emotional manipulation and the risks involved. In conclusion, the article proposes a series of considerations grounded in the ethics of care for the developmental process of AI-powered therapeutic tools.
Implementation of Problem Based Learning (PBL) Model Using Maple Software in Solving a Trigonometry Material Problem
Authors: Ni’mah Dewi Nailin , Inganah Siti , Putri Octavina Rizky Utami
Published: March 2024

This study aims to investigate the implementation and effectiveness of the PBL learning model with Maple Software in solving Trigonometry problems during mathematics lessons. It is descriptive research with a quantitative approach. The participants were 20 tenth-grade students from an vocational school in the second semester of the 2022/2023 academic year. Data were collected through student questionnaires and written tests. The questionnaires assessed student understanding in solving Trigonometry problems with Maple Software, while the tests included 5 questions to evaluate problem-solving skills using the software. The findings indicate that: (1) The PBL model with Maple Software enhances student engagement and effectively solves Trigonometry problems. (2) The PBL model using Maple Software is effective in improving students' problem-solving abilities in Trigonometry.
Development of MATLAB GUI-Based Mathematics Learning Media with ADDIE Model to Enhance Students' Mathematical Connection Ability
Authors: Putra Fikri Haykal Kusuma , Taufik Marhan , Nadlifah Minatun
Published: March 2024

Research was conducted to develop learning media using Matlab GUI to enhance students' connection abilities. The aim was to create media containing valid, practical, and effective arithmetic and geometric sequences and series to support mathematical understanding. The study involved 10 randomly selected eleventh-grade students. Data was collected from validation results, tests, and student questionnaires. The research followed the ADDIE model in five stages: analysis, design, development, implementation, and evaluation. Media validation test results showed 86.5% validity, while student use scored 85.67% for practicality. Effectiveness testing revealed an average student score of 85.84%, demonstrating high effectiveness. These findings indicate that the Matlab GUI-based learning media successfully meet valid, effective, and practical criteria for enhancing students' mathematical connection abilities.
The Effect of Quran Memorization on Mathematical Understanding Ability with Pearson Correlation and Linear Regression
Authors: Jalaludin Paiz , Nuraini Ani , Amigo Royyan , Jahrani Siti , Hamdi At-Taibi Faisal
Published: March 2024

The benefit of memorizing the Quran trigger Islamic education mobilizers to integrate Quran memorization activities as one of the compulsory or extracurricular subjects in formal educational institutions.. This study aims to understand the relationship and influence of the Quran memorization index on students' mathematical abilities. The methods used to answer this problem are the Pearson correlation test and the simple linear regression test. Both statistical methods were rigorously reviewed in this study. The results of this study show that there is a significant relationship between the variable of the Quran memorization index and the mathematical understanding abilities of students at Pondok Pesantren Al-Hasanah Darunnajah 9 with a correlation coefficient of 0.428 which is included in the medium category. In addition, the results showed that there was a positive and significant influence between the Quran memorization index on students' mathematical abilities, where students' mathematical abilities were 18.3% influenced by the Quran memorization index, while the rest were influenced by other factors.
Spleen white pulp structural and cellular composition in experimental furosemide-­induced hypomagnesemia
Authors: Smetanina Marina V. , Chuchkova Natalya N. , Kormilina Natalya V. , Pazinenko Ksenia A.
Published: March 2024

Relevance. Magnesium deficiency in the blood (hypomagnesemia) is due to many reasons, among which loop diuretics (furosemide) occupy acertain place. The role of the spleen in this process has not been determined. The aim of the work was to elucidate the effect of furosemide-­induced hypomagnesemia on the immune structures of the white pulp of rat spleen. Materials and Methods. Furosemide (Lasix® Aventis Pharma Ltd, India) was injected daily intraperitoneally at adose of 30 mg/kg to the experimental group of white outbred rats for 6 days, animals of the control group received an injection of 0.9% NaCl. Investigated: blood serum for the content of magnesium, calcium, sodium and iron; serial sections of the white pulp of the spleen after staining with hematoxylin and eosin to assess the structure and azure-­II-eosin to assess the cellular composition. With amicroscope magnification of 280 times, the ratio (in%) of primary (PLNS) and secondary lymphoid nodules of the spleen (SLNS) was calculated, the following were measured (µm): the diameter of the germinal center (GC), the width of the mantle and marginal zone, the diameter of the periarteriolar lymphoid sheath (PALS). In GC, the peripheral zone of lymphoid nodules, PALS at amagnification of 1500 times per field of view (100 μm2) was counted and presented as apercentage of the number of lymphocytes; macrophages; cells, mitotic and apoptotic elements. Morphometric analysis was carried out using Image ProPlus6.0 software (Media Cybernetics, USA). Statistical processing was carried out using the Statistica 10.0 software package with the determination of the arithmetic mean (M) and its error (m). Results and Discussion. The administration of furosemide led to adecrease in magnesium in the blood serum by 1.6 times (p0.05). In the white pulp of the spleen of animals of the experimental group, the proportion of SLNS decreased by 18.14%, the number of SLNS increased by 42.5% (p0.05). The diameter of SLNS increased insignificantly, the diameter of GC and the width of the marginal zone significantly increased by 27.1 and 24.8%, respectively. The proportion of macrophages increased by 20.6% in GC SLNS, and by 17.0% in PALS. The highest increase in the proportion of cells with signs of apoptosis was found in the periarteriolar lymphoid sheath of experimental animals - 34.6% (p0.05). Conclusion. Furosemide loading causes the development of dyselementosis, with the most significant loss of magnesium (hypomagnesemia) and has apronounced effect on the immune parameters of the spleen, represented by white pulp structures. Therefore, correction of the elemental status and monitoring of the state of the spleen in hypomagnesemia caused by the use of loop diuretics is anecessary element in the prevention of complications associated with the use of diuretic drugs.
An integrated approach to the diagnosis, treatment and prevention of caries in early and preschool age children
Authors: Simonenko Daniil A. , Zhurbenko Veronika A. , Karlash Anastasiya E.
Published: March 2024

Relevance. Dental caries, according to World Health Organization, is one of the most common diseases in children throughout the world. In the absence of timely diagnosis and treatment, the carious process can affect not only the efficiency of chewing function, but also speech, smile and, as a consequence, psychosocial adaptation, as well as the quality of life of the child and family. Despite the fact that the etiological factors have been well known for many years, reducing the number of teeth affected by caries in children still remains an urgent task. This article is a review of information sources about the prevalence, etiology and integrated approach to the diagnosis, treatment and prevention of dental caries in children. The authors analyzed scientific data in the search engines PubMed, Google Scholar and eLibrary. Conclusion . Based on the literature review, a number of modern trends were identified that define a series of key hypotheses that summarize the accumulated material and confirm the prospects and relevance of the problem. The goal is to help clinicians recognize common patterns of caries in children and make appropriate decisions regarding the diagnosis, treatment and prevention of carious lesions, taking into account available methods, materials, knowledge, age and patient history. It is also important to create a comfortable and safe environment during the appointment, as unfamiliarity with a new physical interaction can provoke anxiety as a standard response to uncertainty, which often results in childhood dental phobia, contributing to behavioral resistance to return visits. In general, based on the analysis, we can conclude that the use of an integrated approach to diagnosis and treatment has great potential for achieving better results in working with dental patients of early and preschool age, the development and improvement of which should remain a priority to ensure more complete and effective treatment of children and maintaining their health in the long term.
Study of various adhesive systems’ bond strength for bracket placement
Authors: Almokaddam Hayan , Tuturov Nikolay S. , Katbeh Imad
Published: March 2024

Relevance . Today, the dental market offers a large selection of adhesive systems developed based on various concepts. Improving adhesive technology in orthodontic practice is aimed at simplifying methods of use, improving the composition and ability of adhesion of orthodontic elements to the tooth structure. The aim of this study is to compare the shear bonding strength of different generations of adhesive systems for metal brackets placement. Materials and Methods . The study sample consisted of 40 recently extracted human upper premolars. The premolars were divided into four groups 10 each. The first group used the bond Transbond XT 3M Unitek (USA), the second - Beauty Ortho Bond (Japan), the third - Tetric N bond Universal (Vivapen) (USA) with acid etching with phosphoric acid (LI), the fourth - Tetric N bond Universal (Vivapen) (USA) without acid etching with phosphoric acid. The study used metal brackets for upper premolars (Gemini Bracket MBT, 3M Unitek, USA) with a micro-patterned base, the area of which was defined as 10.61 mm2. Mechanical shear strength tests were carried out using the Instron Universal Test machine (USA). One-way analysis of variance and the TUKEY test were used to examine significant differences in adhesive strength and shear strength between study groups. Results and Discussion. The highest adhesive shear strength was established when using the Transbond XT adhesive system (12.28 MPa) and the Tetric N Bond Universal system using the total etching (12.66 MPa) and self-etching (11.44 MPa) techniques; statistically significant differences between these adhesives were not detected. The second group of Beauty Ortho Bond (5.34 MPa) demonstrated the lowest adhesion force among the studied adhesives, with a statistically significant difference from the other groups. Conclusion : This study concluded that there are no notable differences in the comparison of the universal system with or without etching with the Transbond system. Regarding the use of the beauty Ortho bond, it obtained the lowest strength with significant difference from the remaining groups.
Role of child behavior management in forming positive associations with the dentist
Authors: Lupeychinkova Karina N. , Sorokina Daria S. , Zhurbenko Veronika A. , Karlash Anastasia E.
Published: March 2024

Relevance. The psychological adaptation of achild to adental appointment is of particular relevance today. This study analyzes the literature on the role of child behavior management in pediatric dentistry. The causes of dental fear, its manifestations and consequences are considered. Also, various methods of adaptation of the child and the results of studies evaluating the effectiveness of such methods are analyzed. The goal is to find out which ways of managing achild’s behavior are able to form positive associations with dentists as well as overcome anxiety and fear of treatment. Conclusion. The results of the literature analysis show that even the simplest methods of interaction with children are effective in reducing anxiety and fear before visiting adentist. In addition, working with parents and using various forms of interactive communication helps to create apositive atmosphere in the dental clinic and form apositive experience for children. In general, based on the analysis, it can be concluded that the control of the child’s behavior has great potential to achieve better results in the work of adentist. The development and improvement of methods of controlling the behavior of children in dentistry should remain apriority to ensure more complete and effective treatment, as well as maintaining their health in the long term.
Impact of three types of music on patients during dental implant surgery and wisdom tooth extractions
Authors: Dagher Suzan , Dymnikov Alexander B.
Published: March 2024

Relevance. Many patients suffer from anxiety when planning a surgical procedure, which leads them to either postpone it or go through it with all those negative feelings that may affect the course of the surgical work or even its outcomes. Modern medicine aims to find non-pharmaceutical ways, such as music, to put these emotions under control so that the patient feels a sense of calm and tranquility throughout the surgical operation and comes out with less negative feelings and good memories, which prevents the formation of any psychological trauma. Our investigation aims to study the effect of three types of music, on the psychological state of the patient during surgery, by evaluating the data of systolic and diastolic pressure, pulse, and oxygen level in the blood. Materials and Methods . 36 patients who visited the Medical Center of the RUDN University on a daily basis for dental implants and wisdom tooth extractions were randomly selected to undergo the experiment. They were divided into four groups, the first was the control group which was not exposed to music, the second was exposed to classical music, the third was exposed to Buddhism music, and the fourth was exposed to music generated by Artificial Intelligence. Pressure, pulse, and oxygen level were recorded in three phases and changes assessed using Student’s t-test and Mann-Whitney U analyses. Results and Discussion. The final results obtained did not show any significant changes in the values of pressure, pulse, and blood oxygenation during the period of exposure to music when compared with control group. Conclusion. Exposing to music didn’t show any positive effect on stress levels during dental implantation and extraction.
O coordenador pedagógico e a formação continuada de professores: reflexões sobre educação, escola e diversidades de gêneros
Authors: Correia Georgeton Pires , Santos Cínthia Maria Seibert
Published: March 2024

O presente estudo versa sobre desafios e possibilidades na atuação do coordenador pedagógico, profissional que tem como um dos compromissos inerentes ao seu fazer, manter a sua formação permanente e a formação permanente de professores no âmbito escolar, considerando-se a multiplicidade de desafios frente à concepção de educação e de formação assumida nos contextos formativos e à necessidade de combater preconceitos, violências e silenciamentos ainda presentes na escola e na sociedade, marcadamente em crise: crise moral, crise de valores, crise na formação e na constituição de sujeitos éticos, além da falência na construção de sujeitos políticos e comprometidos com a formação de uma sociedade pautada em relações mais humanas e emancipatórias. Partindo dessa premissa freiriana - uma educação emancipatória -, refletimos sobre a escola como lócus privilegiado de formação de profissionais da educação para discutir temas relacionados às diversidades de gênero e sexualidades como estratégia de combate e de mitigação da violência sofrida por estudantes LGBT.
Corrigendum
Authors: Editorial E
Published: March 2024

CORRIGENDUM by Snezana Mladenovic Drinic, Editor of the journal Genetika
request from Leila Joudi for removal of Name from article due to inaccurate
information RAPD profiling in detecting genetic variation in Stellaria L.
(Caryophyllaceae) Peng X., M. Khayyatnezhad and L. Joudi Ghezeljehmeidan
Original scientific paper https://doi.org/10.2298/GENSR2101349P published
in the journal Genetika, 2021, Vol53, No.1, 349-362. Appendix: Letter from
dr Leila Joudi.

 Link to the corrected article 10.2298/GENSR2101349P
Investigation on genetic diversity of pepper (Capsicum spp.) parents and interspecific hybrids using ISSR markers
Authors: Srebcheva Todorka , Kostova Milena
Published: March 2024

Pepper (Capsicum) is one of the most important and widespread vegetable crops
in the Balkans. Some old indigenous forms are not the focus of modern
breeding but are preserved in some areas and represent valuable genetic
resources. Three Bulgarian varieties (Plovdivska kapiya, Familiya and IZK
Delicates) C. annuum, and two representatives of the chili pepper C.
chinense and C. frutescens. Interspecific hybrids were made between sweet
(C. annum) and chili pepper plants. The genetic relationships of the
varieties of Capsicum species were assessed using ISSR primers. PCR
amplification of isolated DNA from parental lines and interspecific hybrids
revealed 65 distinct polymorphic bands. Cluster analysis clearly
distinguished the parental forms and individuals from the F1 and F2
populations. The applied ISSR molecular technique can be successfully used
to analyze genetic diversity in cultivars, early-stage seedlings, and
interspecific hybrids, as well as to detect differences in individuals whose
genomes are highly homogeneous, such as those of the genus Capsicum.
Estimation of body weight from morphological measurements in Boer goats with the application of artificial neural networks and some regression models
Authors: Tyasi T.L. , Çelik Ş.
Published: March 2024

In this study, examination of the characteristics of body measurements
affecting the body weight of Boer goats and the estimation of the body
weight were investigated. To examine their body morphological features, 400
live animals were taken into consideration. The morphological measurements
taken from the goats in the study were body weight (BW), body length (BL),
heart girth (HG), withers height (WH), rump height (RH), rump length (RL),
ear length (EL) and head with (HW) respectively. These animals were between
1-6 years old; 112 of them were male and 288 of them were female. Multiple
regression, ridge regression and artificial neural networks (ANN) methods
were applied to estimate the body weight. In the prediction of body weight
as a dependent variable, the ANNs predictive model produced high predictive
performance. Mean square error (MSE), mean absolute error (MAD) and mean
absolute percent error (MAPE) statistics were used to determine model
performance. Using the Multi-Layer Perceptron (MLP) Artificial Neural
Network (ANN) learning algorithm, the body features that had the greatest
impact on body weight were determined. Comparison of the predictive
performance of the put forward model against both multiple regression and
state of the ridge regression methods showed that the artificial neural
networks outperformed both competing models by achieving the least values
for MAD, MSE and MAPE in both training and testing data sets. The results of
artificial neural networks were promising and accurate in the prediction of
the body weight of goats.
Stable glioma incidence and increased patient survival over the past two decades in Norway: a nationwide registry-based cohort study
Authors: Skaga Erlend , Trewin-Nybråten Cassia B. , Niehusmann Pitt , Johannesen Tom Børge , Marienhagen Kirsten , Oltedal Leif , Schipman Stephanie , Skjulsvik Anne Jarstein , Solheim Ole , Solheim Tora Skeidsvoll , Sundstrøm Terje , Vik-Mo Einar O. , Petter Brandal  , Ingebrigtsen Tor
Published: March 2024

Background: Surveillance of incidence and survival of central nervous system tumors is essential to monitor disease burden and epidemiological changes, and to allocate health care resources. Here, we describe glioma incidence and survival trends by histopathology group, age, and sex in the Norwegian population.
Material and methods: We included patients with a histologically verified glioma reported to the Cancer Registry of Norway from 2002 to 2021 (N = 7,048). Population size and expected mortality were obtained from Statistics Norway. Cases were followed from diagnosis until death, emigration, or 31 December 2022, whichever came first. We calculated age-standardized incidence rates (ASIR) per 100,000 person-years and age-standardized relative survival (RS). 
Results: The ASIR for histologically verified gliomas was 7.4 (95% CI: 7.3–7.6) and was higher for males (8.8; 95% CI: 8.5–9.1) than females (6.1; 95% CI: 5.9–6.4). Overall incidence was stable over time. Glioblastoma was the most frequent tumor entity (ASIR = 4.2; 95% CI: 4.1–4.4). Overall, glioma patients had a 1-year RS of 63.6% (95% CI: 62.5–64.8%), and a 5-year RS of 32.8% (95% CI: 31.6–33.9%). Females had slightly better survival than males. For most entities, 1- and 5-year RS improved over time (5-year RS for all gliomas 29.0% (2006) and 33.1% (2021), p < 0.001). Across all tumor types, the RS declined with increasing age at diagnosis.
Interpretation: The incidence of gliomas has been stable while patient survival has increased over the past 20 years in Norway. As gliomas represent a heterogeneous group of primary CNS tumors, regular reporting from cancer registries at the histopathology group level is important to monitor disease burden and allocate health care resources in a population.
Normative values in healthy adults for the 6-minute and 2-minute walk tests in Belgium and Vietnam: implications for clinical practice
Authors: Nguyen Duy Thanh , Penta Massimo , Questienne Claire , Garbusinski Johanne , Nguyen Chinh Van , Sauvage Chloé
Published: March 2024

Objective: To establish reference values for the 6-minute walk test (6MWT) and 2-minute walk test (2MWT) distances, to investigate the correlation between these 2 tests, and to establish prediction equations for these distances in healthy populations of Belgium and Vietnam.
Design: Cross-sectional study.
Subjects and methods: The 6MWT and 2MWT were administered to a convenience sample of 239 Belgian and 303 Vietnamese participants between the ages of 18 and 80 years.
Results: The mean (standard deviation; SD) 2MWT distances were 215 (32.8) m for Belgian participants and 156 (25.5) m for Vietnamese participants. The mean (SD) 6MWT distances were 625 (90.7) m for Belgian participants and 449 (70.4) m for Vietnamese participants. The Pearson correlation coefficient between the 2 tests was 0.901 (p < 0.001) for Belgian participants and 0.871 (p < 0.001) for Vietnamese participants. Age and sex were the 2 most important predictors of walking distance, followed by body mass index for Belgium and height for Vietnam. The adjusted R² ranged from 0.31 to 0.49 across 4 predictive equations.
Conclusion: These results can be used to determine the presence of walking performance deficits and to guide future studies. The 2MWT is suggested as a useful and convenient alternative to the 6MWT for assessing walking performance in clinical practice.
CALIBRATION METHODS OF INDUSTRIAL ROBOTS
Authors:   Lviv Polytechnic National University, Pytel Ivan , Vasylyk Maksym ,   Lviv Polytechnic National University, Makal Jaroslaw ,   Bialystok University of Technology
Published: March 2024

Robotization is one of the crucial directions of modernizing today's industrial production. Robotic systems offer solutions to many different challenges. However, their implementation is constrained by limited accuracy, which is inferior to conventional machine tools. A way to improve industrial robots' accuracy is to calibrate them, i.e., eliminate factors that affect accuracy by refining the mathematical models for software correction of manufacturing and assembly errors, as well as elastic and thermal deformations.
FUNDAMENTAL ASPECTS OF METROLOGICAL SUPPORT IN IoT
Authors:   Lviv Polytechnic National University, Honsor Oksana , Mykyichuk Bogdan ,   Lviv Polytechnic National University
Published: March 2024

The application of intelligent sensors, network technologies, and machine learning in IoT and industry is increas- ingly widespread as a part of the development and implementation of Industry 4.0, Industry 5.0, and Smart City. It is necessary to review the fundamental principles of metrological support for production. This includes calibration, estimation of measurement uncertainty, traceability, and processing of large data sets to reproduce and compare the results of measurements of physical quan- tities remotely. Modern smart sensors are cost-effective, which makes traditional sensor calibration methods increasingly uneco- nomical. The utilization of advanced networking technologies, along with machine learning, complicates the pre-processing of measured values. Therefore, new solutions are required when it comes to implementing digital metrology. In this article, a metrological framework for the full life cycle of measured data in IoT is presented. It ensures transparency, comparability, consistent quality and reliability of measured data, processing methods and results. The OPC-UA digital data com- munication standard is considered, which provides a single interface for exchanging digital data with devices from different manu- facturers or via different protocols. The syntax of a machine-readable representation of SI units and derived quantities as well as the structure of the sensor network metadata model are also described. Special emphasis is placed on dynamic calibration of sen- sors, determining measurement uncertainty in sensor networks, and implementing digital calibration certificates in IoT and industry.
Characteristics of Patients with Morbidly Adherent Placenta at Dr. Hasan Sadikin Hospital Bandung
Authors: Aziz Muhammad Alamsyah , Wulandari Dewi Retno
Published: March 2024

AbstractObjective: Morbidly adherent placenta (MAP) is one of the causes of postpartum haemorrhage that impacts morbidity, hysterectomy, and mortality. This study reviewed patient characteristics and disease features in tertiary referral hospital patients with MAP.Methods: This is a quantitative descriptive study conducted on patients with MAP in September 2019–September 2020. Patient data were sourced from medical records. The characteristics described in this study include sociodemographic characteristics, obstetric history (gestation, parity, and abortion), history of caesarean section (CS), history of curettage, comorbidities, and current disease description and outcomes (bleeding, infant outcome, length of stay, death).Result: A total of 24 patients were diagnosed post-operatively as MAP in this study. Most of the patients were multi-parity, had a history of CS or curettage, and had comorbid placenta previa. Most of the patients came for CS plans or went with the chief complaint of bleeding. All patients were managed by hysterectomy. There was one case of maternal death and one case of fetal death.Conclusion: The characteristics of the patients in this study reflect the risk factors and general features of MAP.Karakteristik Pasien MAP di RSUP Dr. Hasan Sadikin BandungAbstrakTujuan: Morbidly adherent placenta (MAP) merupakan salah satu penyebab perdarahan pasca-salin yang berdampak pada morbiditas, tindakan histerektomi, dan mortalitas. Penelitian ini dilakukan untuk meninjau karakteristik pasien dan gambaran penyakit pada pasien dengan MAP di rumah sakit rujukan tersier.Metode: Penelitian ini merupakan deskriptif kuantitatif yang dilakukan pada pasien dengan MAP pada September 2019–September 2020. Data pasien bersumber dari rekam medik. Karakteristik yang dideskripsikan pada penelitian ini meliputi karakteristik sosiodemografi, riwayat obstetrik (gestasi, paritas, dan abortus), riwayat seksio caesarea (SC), riwayat kuretase, komorbid, dan gambaran penyakit terkini serta luarannya (perdarahan, luaran bayi, lama perawatan, kematian).Hasil: Sebanyak 24 pasien yang terdiagnosis pasca-bedah sebagai MAP pada penelitian ini. Sebagian besar pasien multi paritas, memiliki riwayat SC ataupun kuretase, dan memiliki komorbid plasenta previa. Sebagian besar pasien datang untuk rencana SC ataupun datang dengan keluhan utama perdarahan. Semua pasien ditatalaksana dengan histerektomi. Kematian pada ibu terjadi sebanyak satu kasus dan anak terjadi sebanyak satu kasus.Kesimpulan: Karakteristik pasien pada penelitian ini merefleksikan faktor risiko dan gambaran umum MAP.  Kata kunci: morbidly adherent placenta, plasenta akreta, plasenta inkreta, plasenta perkreta.
The Role of Vitamin D and Vitamin D Receptor in Placenta Accreta Spectrum: A Literature Review
Authors: Mirani Putri , Lestari Peby Maulina , Murti Krisna , Liberty Iche Andriyani , Kesty Cindy , Andrina Hana , Stevanny Bella
Published: March 2024

Objective: This study aims to review the role of vitamin D and vitamin D receptor in Placenta Accreta Spectrum Disorder (PASD)Method: This review used several databases, namely Google Scholar, Science Direct, Elsevier, Medline, PubMed, Proquest, dan Wiley Online Library to search original and review articles in English about placenta accreta spectrum, placenta accreta, vitamin D, and vitamin D receptor in the last 10 years. Other reference sources used were guidelines and textbooks.Results: A total of four articles were included in this review.Discussion: Placenta accreta spectrum disorder is becoming more common around the world, owing to the rise in cesarean deliveries. It is linked to several risk factors, including a lack of vitamin D. Vitamin D and its receptor stimulate endometrial decidualization, which aids implantation. Vitamin D receptors in human placental trophoblasts create and respond to 1,25(OH)2D3, which promotes the conversion of endometrial cells to decidual cells. Women with PASD are mostly suffering from vitamin D deficiency. Conclusion: Vitamin D levels may influence trophoblast invasion in PASD and can be a potential diagnostic marker.Peran Vitamin D dan Reseptor Vitamin D dalam Spektrum Plasenta Akreta: Suatu Tinjauan PustakaAbstrakTujuan: Penelitian ini bertujuan untuk meninjau peran vitamin D dan reseptor vitamin D dalam Spektrum Plasenta Akreta (SPA)Metode: Tinjauan pustaka ini menggunakan beberapa sumber data yaitu Google Scholar, Science Direct, Elsevier, Medline, PubMed, Proquest, dan Wiley Online Library untuk mencari artikel penelitian dan tinjauan pustaka dalam Bahasa Inggris mengenai plasenta akreta, vitamin D, dan reseptor vitamin D dalam 10 tahun terakhir. Sumber referensi lain yang digunakan adalah pedoman dan buku teks.Hasil: Sebanyak empat artikel dimasukkan dalam ulasan ini.Diskusi: Spektrum Plasenta Akreta terjadi lebih sering di seluruh dunia karena meningkatnya persalinan sesar. Plasenta akreta terkait dengan beberapa faktor risiko termasuk kekurangan vitamin D. Vitamin D dan reseptornya merangsang desidualisasi endometrium dan berperan dalam implantasi. Reseptor vitamin D pada trofoblas plasenta membuat dan merespons 1,25(OH)2D3 yang mendorong konversi sel endometrium menjadi sel desidua. Mayoritas wanita dengan SPA mengalami kekurangan vitamin D.Kesimpulan: Kadar vitamin D dapat mempengaruhi invasi trofoblas pada SPA dan berpotensi menjadi penanda diagnostik.Kata kunci: spektrum plasenta akreta, reseptor vitamin D, vitamin D
Doppler ultrasound is more accurate than pulse oximeter plethysmography in the measurement of systolic arterial pressure from the median caudal artery in anesthetized dogs
Authors: Whittaker John H. , Kapaldo Nathaniel , Bortoluzzi Eduarda M. , Rankin David C.
Published: March 2024

OBJECTIVE

To compare the accuracy of doppler ultrasound (DOP) and pulse oximeter plethysmography (POP) in the measurement of systolic arterial pressure (SAP) to invasive blood pressure (IBP) in anesthetized dogs.

ANIMALS

40 client-owned healthy dogs > 10 kg.

METHODS

Dogs were anesthetized for surgical procedures in dorsal recumbency. Invasive blood pressure was measured from a dorsal pedal artery. DOP and POP device probes were placed over the median caudal artery with a flow-occluding cuff for noninvasive blood pressure measurement. Systolic arterial pressure measured by DOP, loss of pulse oximeter plethysmograph (POPL), and return of pulse oximeter plethysmograph (POPR) were compared to SAP measured by IBP. A linear mixed model was used to determine correlation. Bland-Altman analyses were performed to determine bias, SD, and limits of agreement. The accuracy of DOP and POP was compared to IBP across different tensive states.

RESULTS

Conditional R2 values for DOP, POPL, and POPR versus IBP were 0.92, 0.85, and 0.87, respectively (all P < .001). The biases for DOP, POPL, and POPR compared to IBP were +7.6 ± 13.1, +3.9 ± 14.4, and +8.6 ± 15.2 mm Hg (bias ± SD), respectively. Limits of agreement (lower, upper) were (−18.1, +33.3), (−24.3, +32.1), and (−21.2, +38.4) mm Hg for DOP, POPL, and POPR, respectively. DOP and POP overestimated SAP during hypotension (SAP < 90 mm Hg), DOP to a lesser magnitude.

CLINICAL RELEVANCE

DOP measured from the median caudal artery may be acceptable for SAP measurement in dorsally recumbent, healthy anesthetized dogs > 10 kg. POP was determined an unacceptable method.
New Moorish architectural identity in Tlemcen, Algeria
Authors: Mazouz Fatima , Triqui Manar
Published: March 2024

In Algeria, the city of Tlemcen is home to 60% of the country’s Arab-Islamic architectural heritage, also known as Moorish. During the French colonization, the rich Moorish historical and architectural heritage was largely diminished. The architecture of Tlemcen’s historic old town was gradually replaced by classical architecture in the early days of colonization, and then by modern architecture from 1940 onwards. After the independence in 1962, the city has carried out huge programs of facilities and new housing, based on modern architectural principles. In 2011, Tlemcen was designated a “Capital of Islamic Culture” and, in preparation for this international cultural event, new cultural facilities and hotels have been built, inspired by Moorish heritage. Given the heterogeneity of references and in particular the identity crisis ensuing in architecture in Tlemcen, this event was the key moment for validating a stylistic choice, which directly recounts the history of the city. The question is: what authenticity is expressed by the current use of the Moorish referent? Is it technical and material authenticity, or merely symbolic and cultural genuineness? This study delves into the question of identity in architecture. It analyses the new Moorish-style buildings in Tlemcen and highlights their contribution to the quest for a local identity and the ambition to produce local architecture. The article supports the hypothesis that architecture is an effective means of expressing identity and that it has always had, and continues to have, a close relationship with memory. The methodology is based on a combination of several investigative tools: surveys, photographs and archive consultation. These tools helped develop a building analysis grid, which serves as a repertory for describing the buildings, according to two levels of reading of the architectural work. We have chosen three Moorish and four contemporary buildings to which the different criteria of the analysis grid are applied. The results of the analysis of the new buildings show that, in a way, they enabled to establish continuity and dialogue with the Moorish heritage.