bluuebunny/crossref_metadata_2025 huggingface dataset:
Safety and efficacy of Ketamine in a patient with psychotic depression, cardiovascular disease, and starvation risk
Authors: Trejos Orozco Efraín Alberto , Gutiérrez Segura Julio César , Ochoa Orozco Sergio Andrés
Published: September 2022

Introduction: There has been a rising interest in ketamine as a promising treatment for refractory depression. Despite this, there is uncertain knowledge regarding aspects of the routinary use of ketamine for treating depression, such as optimal doses, long term toxicity, abuse potential in depressed patients, probable adverse effects associated with antidepressant drugs, the indication of ketamine in psychotic patients, and the ethical concerns of ketamine use.

Clinical case: A 63 year-old woman with a psychotic depressive episode, catatonic features, cardiovascular disease (patent foramen ovale and atrial fibrillation) , and starvation risk because she refused food intake. She was sent to electroconvulsive therapy (ECT) after several weeks of oral administration of benzodiazepine, antipsychotic, and antidepressant medications; the patient presented no improvement, but she was rejected due to her cardiovascular comorbidity. Two IV Ketamine doses were used as a life-saving strategy with good clinical response, mainly in terms of the catatonic features. The ketamine treatment was not only effective but also well tolerated.

Discussion: Despite the little information regarding its use in psychotic and catatonic patients, this case would suggest that it remains effective and safe, as well as a good option for patients with cardiovascular disease and those who cannot use electroconvulsive therapy.
Metatranscriptomics reveals higher species compositional homogeneity in smaller size coral reef zooplankton
Authors: Mattos Felipe , Fong Chia-Lin , Dreyer Niklas , Wen Yung-Hui , Jain Dharmesh , Vivo Mattia De , Huang Yu-Sin , Mwihaki John , Wang Tzi-Yuan , Ho Ming-Jay , Tsai Isheng J. , Wang John , Chan Benny , Machida Ryuji
Published: September 2022

Marine drifting animals — zooplankton — play essential ecological
roles in the pelagic ecosystem, transferring energy and elements to
higher trophic levels, such as fishes, cetaceans, and others.
Zooplankton are generally considered passive drifting organisms
homogeneously distributed throughout waters, where high dispersal is
expected. Although empirical observations have demonstrated that many
species possess active swimming mechanisms that generate metacommunities
with high beta diversity, the role of animal sizes in the process of
marine zooplankton community dynamics remains unexplored. Here, we
collected a total of 48 size-fractionated zooplankton samples in the
vicinity of a coral reef island with environmental gradients and
performed metatranscriptome analyses. The samples were collected in two
transects (from nearshore to offshore) twice a day (morning and night).
Sample size fraction was the only variable that rendered apparent
differences in species composition between the samples. Our results
demonstrate differential dispersal through the size fractions —
smaller size fraction communities had higher compositional homogeneity
than larger ones. Contrary to expectation, distance to shore had no
significant influence on the composition or diversity of zooplankton
communities. This study offers novel insights on the use of
metatranscriptomics for analyzing community structures and the role size
plays for the marine zooplankton community assembly processes.
Bladder Care Following Benign Non-Hysterectomy Gynecological Laparoscopy: A Randomized Clinical Trial
Authors: McCormack Lalla , Song Sophia , Budden Aaron , Ma Christine , Nguyen Kimberly , Li Fiona , Lim Claire Yinn , Maheux-Lacroix Sarah , Arnold Amy , Deans Rebecca , Won Haryun , Knapman Blake , Hawes Erin Nesbitt , Abbott Jason
Published: September 2022

Abstract Objective: To compare rates of urinary retention and
postoperative urinary tract infection between women with immediate
versus delayed removal of indwelling catheter following benign
non-hysterectomy gynecological laparoscopic surgery. Design: This
randomized clinical trial was conducted between February 2012 and
December 2019, with follow-up to six weeks, in two university-affiliated
hospitals in Sydney, Australia. Population: Study participants were 693
women over 18 years of age, undergoing non-hysterectomy laparoscopy for
benign gynecological conditions, excluding pelvic floor or concomitant
bowel surgery. Methods: 355 participants were randomized to immediate,
and 338 to delayed removal of urinary catheter. Main Outcome Measures:
The co-primary outcomes were urinary retention (assessed by trial of
void and need to re-catheterize) and urinary tract infection. Secondary
outcomes included readmission, analgesia requirements, duration of
hospitalization and validated bladder function questionnaires. Results:
Urinary retention for participants in the immediate removal group was
statistically higher at 8.2% (95% CI: 5.7% to 11.4%) vs. 4.2% (95%
CI: 2.7% to 7.2%) in the delayed removal group (p=.03). There was no
statistically significant difference in the rates of urinary tract
infection between the groups at 7.2% (95% CI:4.7% to 10.8%) in the
delayed group vs. 4.7% (95% CI: 2.8% to 7.8%) in the immediate
group. Conclusions: Rates of urinary retention and urinary tract
infection following non-hysterectomy benign gynecological laparoscopy
are low. There is a small increased risk of urinary retention with
immediate compared with delayed removal of urinary catheter. These
findings can be used to counsel patients regarding postoperative bladder
care.
Accessing termination of pregnancy due to fetal anomaly during COVID-19 in South Australia: A qualitative case study
Authors: Watson Amy , Coombe Brigid , Prichard Ivanka , Mulligan Ea , Shipman Jessica
Published: September 2022

Objective Examine experiences of termination of pregnancy (TOP) in South
Australia to recommend areas for service improvement following
decriminalisation legislation. Design Qualitative case study. Setting
Online semi-structured interview. Participants The case study was an
example of the unheard, complex and distressing circumstance of TOP due
to fetal anomaly diagnosis. The case was selected from larger sample
(N=8) of adults who had recently had a TOP in South Australia as a
subgroup from a larger study looking at the potential missed
opportunities of health professionals to provide access to contraception
prior to abortion. Methods Semi-structured, in depth, qualitative
interview. Qualitative description using thematic content analysis
identified significant aspects of the participant’s story pertaining to
potential health service improvements. Results The participant
experienced trauma navigating a difficult care pathway following a
diagnosis of fetal anomaly. They described inadequacy of labels for
pregnancy such as planned, unplanned, wanted, unwanted, the framing of
abortion through the lens of ‘choice’, and confusion about service
referrals and inappropriate communication by health professionals. Not
being able to have a partner accompany her through the process of having
a TOP due to COVID-19 restrictions resulted in extreme distress.
Conclusion Abortion services need clear care pathways that are context
specific, and patient centred. The language and attitudes of health
professionals can result in distressing experiences of TOP. Further
investigation of the relationship between infection control strategies
and trauma in health service provision is warranted to improve future
pandemic responses.
Characteristic Time Scales of Reservoir Evaporation in a Subarctic Climate
Authors: Pierre Adrien , Nadeau Daniel , Thiboult Antoine , Rousseau Alain N. , Tremblay Alain , Isabelle Pierre-Erik , Anctil François
Published: September 2022

Water bodies such as lakes and reservoirs affect the regional climate by
acting as heat sinks and sources through the evaporation of substantial
quantities of water over several months of the year. Unfortunately,
energy exchange observations between inland water bodies and the
atmosphere remain rare in northeastern North America, which has one of
the highest densities of lakes in the world. This study helps to fill
this gap by analyzing field observations collected from a subarctic
hydropower reservoir (50.69°N, 63.24°W) characterized by a mean depth of
44 m and a surface area of 85 km . Two eddy
covariance (EC) systems, one on a raft and one onshore, were deployed
from 27 June 2018 to 12 June 2022. The thermal regime of the reservoir
was monitored using vertical chains of thermistors. Results indicate a
mean annual evaporation rate of 590 ± 66 mm (~70% of
the annual precipitation), with 84% of the evaporation occurring at a
high rate from August to freeze-up in late December through episodic
pulses. It was difficult to close the energy balance because of the
magnitude and the large time lag of the heat storage term. In order to
circumvent this problem, we opted to perform calculations for a year
that started from the first of March, as the heat storage in the water
column was at its lowest at that point and could thus be ignored. From
June to December, monthly Bowen ratios increased from near-zero negative
values to about 1.5. After September, due to smaller vapor pressure
deficits, latent heat fluxes steadily declined until an ice cover sealed
up the reservoir. Two opposite diurnal cycles of sensible and latent
heat fluxes were revealed during the open water period, with sensible
heat fluxes peaking at night and latent heat fluxes peaking in the
afternoon.
CONCEITOS DE CONTABILIDADE PRECONIZADOS PELOS PROFESSORES E SUAS RELAÇÕES COM O DESEMPENHO DISCENTE
Authors: Rodrigues de Lames Edilei , José Miranda Gilberto
Published: September 2022

Este artigo tem como objetivo analisar se a compreensão dos conceitos de contabilidade, pelo docente, está associada ao rendimento dos alunos, medido pela performance destes nos Exames de Suficiência do CFC. O estudo é exploratório-descritivo, com abordagem quantitativa e faz uso de um questionário aplicado a 433 docentes em Ciências Contábeis no Brasil, além da base de dados do Exame de Suficiência do CFC. Para a análise dos dados utilizou-se da estatística descritiva e inferencial (Análise de Correlação e Regressão Beta). Os resultados indicam que os docentes com publicações em revistas de alto impacto, que possuem o doutorado há mais tempo e atuam há menos tempo na docência, sãos os que melhor contribuem para a aprovação no Exame de Suficiência. Observa-se que há correlação estatisticamente significativa com o rendimento discente no Exame de Suficiência em quatro dos seis conceitos de contabilidade analisados. Os conceitos de Ciência, Ciência Social Aplicada e Arte evidenciam implicações negativas no rendimento discente, enquanto os resultados para o conceito de Contabilidade como Representação da Realidade sugerem que o docente que aceita este conceito tende a melhor capacitar os alunos para o exercício da profissão, pelo maior percentual de aprovação no Exame de Suficiência do CFC, apesar de não terem sido sustentados pela regressão beta. Conclui-se que a compreensão que os docentes têm dos conceitos de contabilidade e sobretudo das limitações desta no processo decisório, tem interferido no rendimento discente.
Federating digital contact tracing using structured overlay networks
Authors: Ghilezan Silvia , Kasterovic Simona , Liquori Luigi , Marinkovic Bojan , Ognjanovic Zoran , Stefanovic Tamara
Published: September 2022

In this paper, we present a comprehensive, yet simple, extension to the existing systems used for Digital Contact Tracing in Covid-19 pandemic. The extension, called BubbleAntiCovid19 (BAC19), enables those systems, regardless of their underlying protocol, to enhance their sets of traced contacts and to improve the global fight against pandemic during the phase of opening borders and enabling more traveling. BAC19 is a Structured Overlay Network. Its protocol is inspired by the Chord and Synapse Structured Overlay Networks. We design the architecture of the Overlay Network Federation. We show that the federation can be used as a formal model of Forward Contact Tracing. BAC19 provides a fully exhaustive retrieving procedure thanks to avoiding search during peer churn. Furthermore, we give simulation results for the BAC19 system, the simulator written in Python.
Case 12: Acromegaly Presenting With Diabetic Ketoacidosis
Authors: Verma Ritika , Huynh Kiet , Gundluru Rajani , Gardner Michael , Sowers James
Published: September 2022

We present a 31-year-old male without any comorbidities who presented to the emergency room (ER) with a 2-week history of polyuria, polydipsia, constipation, and fatigue. He also reported a weight loss of 40 lb over the last 3 months. During the interview, he mentioned having oily skin and acne all of his life. He denied palpitations, hyperhidrosis, or difficulty with sexual activity. Physical exam was striking for frontal bossing, prognathism, hypertrichosis, and large hands and feet, suggesting acromegaly. No acanthosis nigricans or acrochordons was noted. Initial lab work revealed the following: blood glucose 241 mg/dL, serum bicarbonate 12 mEq/L, anion gap 31, β-hydroxybutyrate >8 mmol/L, ketonuria on urinalysis, and HbA1c of 13.1%. Islet cell anti-GAD antibodies were negative.
Case 13: Rapid-Onset Type 1 Diabetes and Ketoacidosis
Authors: Rimmalapudi Deepthi , Ipp Eli
Published: September 2022

A 54-year-old Hispanic male presented to the emergency department with a 2-day history of nausea, vomiting, polydipsia, and generalized weakness. He was found to be in severe diabetic ketoacidosis with serum glucose of 1,062 mg/dL, pH of 6.84, HCO3 of 5 mmol/L, anion gap of 25, and β-hydroxybutyrate of 11 mmol/L. He denied a previous history of diabetes, but was told 1 year earlier that he had prediabetes and was treated with diet. He was managed in the intensive care unit (ICU) with fluid and electrolyte resuscitation and insulin infusion and was switched to a basal-bolus insulin regimen once ketoacidosis resolved.
Case 14: Euglycemic Ketoacidosis in the Setting of COVID-19 Infection and Sodium–Glucose Cotransporter 2 Inhibitor Use
Authors: Duchon Olga , Thomas Celeste
Published: September 2022

A 26-year-old man with a 3-year history of type 2 diabetes was admitted to the hospital with respiratory illness and abdominal symptoms attributed to coronavirus disease 2019 (COVID-19) infection. He had a history of intermittent insulin use and three or four hospital admissions for diabetic ketoacidosis (DKA) within the first 2 years of diagnosis. In the 3 months before this admission, he again discontinued insulin therapy but continued the sodium–glucose cotransporter 2 (SGLT2) inhibitor canagliflozin and glipizide that was prescribed by his primary care provider.
Case 16: A Case of Euglycemic Diabetic Ketoacidosis After Initiation of Ketogenic Diet in a Patient With Type 2 Diabetes on a Sodium–Glucose Cotransporter 2 (SGLT2) Inhibitor
Authors: Gilbert Matthew , Shah Amy
Published: September 2022

A 52-year-old Caucasian female with a past medical history of well-controlled type 2 diabetes, hypertension, and dyslipidemia presented to the emergency department with a 3-day history of severe headache associated with nausea, neck pain, and photophobia. Her outpatient diabetes regimen consisted of metformin 1,000 mg twice a day, linagliptin (a dipeptidyl peptidase-4 [DPP-4] inhibitor) 5 mg daily, and empagliflozin (a sodium–glucose cotransporter 2 [SGLT2] inhibitor) 25 mg daily. She reported starting a ketogenic diet 4 months before admission with an objective 17-lb weight loss after she had prior success with extremely low-carbohydrate/ketogenic diets in the past.
Case 19: Immune Checkpoint Inhibitor–Induced Type 1 Diabetes
Authors: Kaan Akturk Halis , Michels Aaron
Published: September 2022

A 64-year-old Caucasian male with no previous history of diabetes presented with nausea, vomiting, fatigue, increased urination, and thirst over the 3 days before presentation, along with worsening of his mental status. He was being treated with pembrolizumab (monoclonal antibody targeting programmed cell death receptor-1 [PD-1]) infusions for advanced lung cancer. His most recent dose was 3 days before presentation, and his first dose was 24 days prior. He had a normal BMI (24.8 kg/m2), and the only pertinent past medical history was hypertension before the diagnosis of lung cancer. He has a 40–pack-year history of smoking. He had not been treated with glucocorticoids recently.
Case 28: Illusion of Autoimmune Diabetes
Authors: Aung Nay Linn
Published: September 2022

A 62-year-old Caucasian woman with a history of hypertension was diagnosed with type 2 diabetes at the age of 56 years during a routine medical checkup. She was started on metformin, and later empagliflozin and glipizide were added. However, the patient stopped taking metformin because of gastrointestinal side effects after a few months.
Case 31: A Novel Approach to Achieve Target Time in Range When Using U-500 Regular Insulin in a Continuous Subcutaneous Insulin Infusion (CSII) Pump
Authors: Montesinos Patricia , Magee Michelle
Published: September 2022

A 58-year-old African American male had type 2 diabetes and insulin resistance with persistent dysglycemia characterized by high glucose variability and suboptimal blood glucose time in range (TIR) (42.5%). His past medical history was remarkable for hypertension, hyperlipidemia, stage 3–4 chronic kidney disease, peripheral neuropathy, gastroparesis, and coronary artery and peripheral vascular disease.
Case 32: Automated Insulin Infusion System Is Useful to Control Blood Glucose Concentration During Major Stress in Patients With Type 1 Diabetes
Authors: Cordera Renzo , Maggi Davide
Published: September 2022

The patient is a 54-year-old female with longstanding (37 years) type 1 diabetes complicated by acropathy and nonproliferative retinopathy. For years, her blood glucose control has been suboptimal, with HbA1c ranging from 7.8–8.6% along with hypoglycemia. Seven months prior, she began using the MiniMed 670G to infuse insulin with improved glucose control, as reflected by time in range and HbA1c.
Case 39: Simplifying Insulin Therapy: Transitioning from Basal-Bolus Insulin Therapy to Basal Insulin With a Glucagon-Like Peptide-1 Receptor Analog (GLP-1RA)
Authors: Aliyeva Sevil , Schroeder Pamela , Sack Paul
Published: September 2022

A 74-year-old African American woman with hypertension, hyperlipidemia, coronary artery disease, and recent stroke was seen for follow-up of type 2 diabetes complicated by retinopathy and peripheral neuropathy.
At-home Bleaching with a Novel Carbamide Peroxide Polymeric Nanoparticle Gel: A Multicenter Randomized Controlled Trial
Authors: Favoreto MW , Hass V , Maran BM , de Paula E , Wachter F , Lima SNL , de Jesus Tavarez RR , Reis A , Loguercio AD
Published: September 2022

Objectives

To compare the risk and intensity of tooth sensitivity (TS) as well the effectiveness of at-home bleaching using two carbamide peroxide bleaching gels, specifically a novel polymeric nanoparticle gel (experimental) and a commercial gel (Opalescence PF, Ultradent, South Jordan, Utah, USA), applied at two application times.

Methods

This multicenter, triple-blind, and split-mouth randomized controlled trial was conducted on 80 healthy adults with canine teeth that were shade A2 or darker. The participants all used the experimental and the control gels on one side of a tray, depending on the group to which they were allocated, for 30 or 60 minutes per day over four weeks. The absolute risk and intensity of TS were assessed daily using the five-point Numeric Rating Scale and the 0–10 Visual Analogue Scale. Color change was evaluated with shade guide units (ΔSGU) and a digital spectrophotometer (ΔEab, ΔE00, and ΔWid) at baseline and 30 days postbleaching. The risk and intensity of TS was evaluated by the McNemar and the Wilcoxon signed-rank tests, respectively. Color change (ΔSGU, ΔEab, ΔE00, and ΔWid) was evaluated by Mann–Whitney and paired t-tests (α=0.05).

Results

No differences in the risk and intensity of TS were observed based on the bleaching gels used and the times of application (p>0.05). Thirty days after bleaching, there was no significant difference in color change, in terms of the bleaching gels used or the application times (p>0.05).

Conclusion

The novel carbamide peroxide polymeric nanoparticles gel, when applied for 30 or 60 minutes, produced effective color change and a low rate of tooth sensitivity, as compared to the control group.
Kuka kuuluu tieteelliseen seuraan? Raportti tieteellisten seurojen jäsenistökyselyn tuloksista
Authors: Late Elina , Pölönen Janne , Pylvänäinen Elina
Published: September 2022

Tieteellisten seurain valtuuskunta (TSV) teetti vuonna 2022 selvityksen tieteellisten seurojen jäsenistöä koskien. Selvityksen tavoitteena oli kerätä tietoa suomalaisten ja kansainvälisten tieteellisten seurojen jäsenistöstä ja tieteellisten lehtien lukemisen käytännöistä. Aineisto selvitystä varten kerättiin kyselyllä ”Kuka kuuluu tieteelliseen seuraan?”, joka osoitettiin tieteellisten seurojen jäsenille ja Suomessa toimiville tutkijoille.
On Autism: One Case
Authors: Cusack Paul TE
Published: September 2022

In this paper, we develop an equation for Autism. We make use of detailed knowledge of his diet and behaviour. The basic problem is that he has too much serotonin which enlivens the senses. It’s the opposite of depression.
COVID-19 Implication by Physical Interaction of Artificial fog on Respiratory Aerosols
Authors: Shum Mona
Published: September 2022

Background: Artificial fog consists of small liquid aerosols suspended in air which reduce visibility and reflect light. Artificial fog is used in the film, television, and live entertainment industries to enhance lighting, as a visual effect, and to create a specific sense of mood or atmosphere. Objective: This study investigated the suspension time for liquid respiratory aerosols spiked with tagged deoxyribonucleic acid (DNA) tracers in the presence and absence of glycerin- or glycol-containing artificial fogs. Methods: Liquid respiratory aerosols with tagged DNA tracers were sprayed into a closed environment without and with glycerin- or glycol-containing artificial fog, with air samples taken at regular intervals to determine the decay of tagged DNA tracer over time. The study treatments included Control (no fog), Glycerin Low (~3 mg/m3 ), Glycerin High (~15 mg/m3 ), Glycol Low (~5 mg/m3 ), and Glycol High (~40 mg/m3 ). Results: All artificial fog treatments had lower mean log reduction curves compared to the Control treatment. The differences in mean log reduction for artificial fog treatments vs. control treatments were all statistically significant (p<0.001), except for Glycerin Low treatment (p=0.087). The differences in mean log reduction between treatments using glycerin fog (p=0.129) and glycol fog (p=0.209) were not statistically significant. Conclusion: Artificial fog use does not increase suspension time of liquid respiratory aerosols, and therefore does not appear to increase the risk of airborne transmission of diseases from liquid respiratory aerosols, such as COVID-19. The suspension time of aerosols in glycol-containing artificial fog decreased more than glycerin-containing fog. In practice, the additional reduction in suspension time provided by the physical interaction of liquid respiratory aerosols with artificial fog does not suggest any practical benefit for using artificial fog as a control measure.
Farm mechanization is the key to provide a number of economic and social advantages to farmers. The most important of the economic benefits is the enhanced yield that comes as a result of increased mechanisation. Combination of mechanical linkage or systems replacing by some electronic components it’s become mechanical + Electronics = Mechatronics. Linear actuator is best example of mechatronics in term of combination of electronic and mechanical. In linear actuator no need to any hydraulic link, distributor, oil tank, hydraulic pump. In some cases its give better then the hydraulic control actuating devices. If we use mechatronics technologies into agriculture sector there have helpful in controlling system and compactness in whole mechanism.
Authors: Pal Singh Lakhwinder
Published: September 2022

Noise is one of the most prevailing environment factor whether inside industry, traffic, agricultural implements, defense machinery etc. Noise pollution is increasing day by and becoming a cause of stress and irritation. The present study envisage to investigate the effect of noise pollution due a forging industry (ABC) on people and surroundings so as to reduce its effects and attempt to find the measures for control of noise levels. The results of the study revealed that noise level during forging operations exceeds the permissible limits of 75 dB (A) and 70 dB (A) during day and night. The same resulted in noise annoyance and sleep disturbance nearby among the residents of village XYZ. After collecting noise data at different places around the industry and data is analyzed, implementation of the control measures so as to reduce the noise level which is under permissible limit prescribed by the Pollution Control Board.
Case Studies on the Body Postures and Technical Design of Small Angle Grinders
Authors: Landau Kurt
Published: September 2022

Our case studies refer to small angle grinders. Work tasks, physical stresses during use, and stresses on the hand-arm system are discussed. For this purpose, a survey was administered to 42 work persons from four different industries. Angle grinders were the most important hand tools for the respondents. They used angle grinders for eight activities (from flexing to polishing). In addition, 17 detailed video analyses of the work processes with 5 different angle grinder makes were carried out in selected workshops. The survey results on working postures in the last week as well as within the last year indicated mainly bent and twisted trunk postures, squatting and kneeling at work. To that extent, these results correspond with the OWAS studies by Ellegast R, et al. The video studies pointed out the very frequent twisted or bent hand-arm postures. The (ergonomically recommended) alignment of tool axis and hand-arm axis is not possible when using angle grinders. Nevertheless, the vast majority of our test subjects are satisfied with the dimensions and characteristics of small angle grinders. The analysis results are transferred into a list of ergonomic requirements for product designers.
Multi-Drug Resistance Patterns of Wound Causing Bacterial Infections in a Rural Hospital, Sirajganj, Bangladesh
Authors: Zakerin Abedin Mohammad
Published: September 2022

Wound infection is considered as one of the most common nosocomial infections in the world. The aim of this study is profiling of bacterial pathogenic isolates from wound infected patients who were admitted to the hospital and commonly to measure antimicrobial susceptibility profiling. An entire of 58 samples were collected for the study. The cultural analysis was done by phenotypic examination, and we performed Gram staining and biochemical examination for identification. The pus and wound swabs were collected aseptically and gold standard microbiological cultural analysis was performed in AlHera General Hospital, Sirajganj, Bangladesh between September 2020 and August 2021. 43(74.1%) of the whole samples yielded positive cultures and only 15(25.9%) samples showed negative growth. Gram-Negative bacteria showed more prevalence than Gram-Positive bacteria which were in number 32 and 11 respectively and in at 74.4% and 25.6%. The most predominant isolate was Escherichia coli 18 (41.9%) and second most was Staphylococcus aureus 12(27.9%), and the rest of other bacterial isolates were Pseudomonas aeruginosa was 5(11.6%), Proteus mirabilis 3(7.0%), Serratia marcescens 2(4.7%), Staphylococcus Saprophyticus 2(4.7%) and Klebsiella pneumoniae 1(2.3%). The isolates were resistant to the commonly used oral antibiotics, namely Azithromycin, Amoxicilin, Ceftriaxone, Ceftazidime, Chloramphenicol, Cefixime, Amoxyclav, Colistin, Cefuroxime, Cloxacillin, Ciprofloxacin, Imipenem, Levofloxacilin, Vancomycin, Linezolid, Meropenem, Erythromycin, Gentamycin, Cephradine, Cotrimoxazole, Moxifloxacin which is very alarming. The pathogens showed remarkable sensitivity against Gentamicin and Meropenem, which at least leaves a window to get treated. This study was performed to hunt out appropriate antibiotic/s for wound infections based on pathogens isolated from wounds of hospital admitted patients in Bangladesh and their antibiotic susceptibility profile against available and frequently prescribed antibiotics.
Food for the Stomach Nourishing our Future: Assessment of Potassium Bromate in Local and Packaged Bread Sold in Ilorin Metropolis
Authors: Lateefat Habeeb Modupe
Published: September 2022

Bread is an important food type created by cooking a batter of flour and water, possibly with other condiments. Potassium bromate is a flour improver that acts as an enhancer. It mostly operates in the late batter stage, energizing the mixture during late sealing and early baking. In Nigeria, the use of bromate in bread production was prohibited in 1993. Regardless, some bread manufacturers have continued to include potassium bromate in their products. Because of its widespread use, this analysis attempts to assess the concentration of Bromate in local and packaged breads sold in the Ilorin Metropolitan Area. It is cross-sectional descriptive research with laboratory analysis. A total of fifteen brands of breads were used in this study labeled as (A,B,C,D,G,J,O,K) as packaged bread and (E,I,L,M,N,E,H) as local bread. They were purchased randomly from bakeries, bus stops and markets in Ilorin, Kwara State Capital, and Nigeria. The bread was subjected to qualitative and quantitative analysis of Potassium bromate in bread. The qualitative result revealed black spot on the samples indicating the presence of potassium bromate. Three of the bread samples (J, L and O) did not show any visible black spot while other bread samples have black spot. The quantitative amount of potassium bromates found in each bread sample showed that the quantity of potassium bromates found in the different bread sample is above Food and Drug Agency (FDA) recommended standards, which is 0.02μg/g (0.02mg/ kg), with sample (M) having the highest concentration (0.62515) of potassium bromate, while sample (E) having the lowest concentration (0.42713) of potassium bromate. The outcome gotten from the research investigation actually inferred that consumer of bread sold in Ilorin are unaware of this harmful substance, notwithstanding a few existing enactments banning its utilization. The net cancer-causing impact of potassium bromate is accumulative, in this way consistency in consumption of bread with potassium bromate could prompt malignant growth over time. The principal issue in Nigeria is execution of the ban and immediate impacts are needed to abridge the utilization of this food poison.
Fair Strategies to Tackle Unfair Risks? Bacteriological Assessment of Food and Water Prepared in Standard Hotels in Abuja Metropolis, Fct, Niger
Authors: Lateefat Habeeb Modupe
Published: September 2022

In Nigeria, with a populace of more than 170 million individuals it was accounted for that just 90,000 cases of food borne ailments happen every year. There was also a report of 60 cases and 3 deaths due to food borne disease with symptomatic gastro intestinal disorders among people who ate in a funeral service. In Nigeria, food safety is not given high preference. Since the hospitality industries manages giving food, drink or convenience to individuals who are away from home, food contamination may emerge at whatever point there is unhygienic food preparation. The study seeks to assess the bacteriological assessment of food and water prepared in standard hotels in Abuja. The study made use of a descriptive cross-sectional study with stratified purposive sampling technique, hotels with 3, 4 and 5 star ratings in Abuja were selected for this study, 45 foods and water samples were aseptically collected for this study. The instrument for data collection was sterile container for sample collection. Data were analysed using, SPSS version 23.0 to present inferential statistics (ANOVA) and descriptive statistics (charts and tables). Staphylococcus aureus (69.75%), Pseudomonas aeruginosa (20%), E. coli (33.75%) and Bacillus spp (18.2%) were isolated in the food samples while E. coli (48%), S. aureus (77.5%), P. aeroginosa (27%), P. vulgaris (12%) Shigella dysentriae (6%) were isolated in water samples. The percentage occurrence of bacteria isolated in the samples were in compliance with the WHO limit for microorganisms in food and water (105 ) cfu/m. This could be as a result of the poor food handling practices carried out in the hotels. However, According to WHO, there should be zero tolerance of E. coli and Samonella typhii, in food and water because at low levels they can still pose risk to health. The results from this study will enable health inspectors and food handlers in hotels to implement stringent food safety methods like HACCP in hotels of their standard to bring about satisfaction and safety of food in their hotels.
Response to the Covid-19 Pandemic: Looking Back and Looking Forward from the Perspective of Local Health Departments in Nebraska
Authors: Palm David
Published: September 2022

Context: The scale and complexity of the COVID-19 pandemic response has revealed some significant successes and limitations of our public health system. Objective: Focused on the pandemic response from the viewpoint of local health departments (LHDs) in Nebraska, this study aimed to identify successes, barriers, lessons learned, and changes needed to improve the local response for future pandemics. Methods: A mixed-methods approach was used to gather information from LHDs in Nebraska. In June 2021, a survey was sent to all LHD directors (n=19), and 17 (89%) participated in the survey. To supplement the survey results, four LHD directors from different areas of the state were interviewed. Results: Successful efforts of the pandemic response included developing stronger partnerships with K-12 schools, distributing the COVID-19 vaccines, and expanding the number of people reached through contact tracing. Barriers included a shortage of staff with the competencies and expertise to respond to a crisis, the lack of funding prior to the pandemic, inconsistent guidance, the politicization of the COVID-19 response, resistance to masking, and misinformation about COVID-19. Conclusions: This pandemic taught many lessons, including the importance of timely and frequent communication with all partners and the public, the need to share accurate data broadly and frequently as possible, the lack of knowledge of public health’s authority to implement emergency public health measures (e.g., quarantine and isolation), and the persistence of staff burnout and retention. Looking forward, baseline funding for LHDs should be expanded to strengthen capacity to hire additional staff, particularly in the areas of epidemiology and communications. Additional investments in common information technology platforms are also essential. Finally, more creative staff resilience solutions are needed to address staff burnout. While essential for LHDs during times of pandemic, such investments can also benefit LHDs when pandemics don’t rage.
TLR 1,3 Receptor Gene Polymorphism in Egyptian Patients With Behcets Disease
Authors: A Abdelmoktader
Published: September 2022

Behçet’s disease (BD) is a multisystem inflammatory disease characterized by recurrent orogenital ulcerations, ocular inflammations, and skin lesions. The ethology of the disease is currently unknown but evidences suggested that there is a strong genetic component mediating the chronicity of the disorder. The disease is characterized by infiltration of lymphocytes and neutrophils into the affected organs. APCs (Antigen Presenting Cells): It express receptor called (TLR) Toll like receptor which are one of PRR (pattern recognition receptor) and essential components of the innate immune system and they are a class of proteins play a key role in the innate immune system ,recognize structurally conserved molecules derived from microbes. This study aimed at investigating the possible associations between two SNPs (Single Nucleotide Polymorphisms) at TLR1 gene and TLR3 gene and BD in 87 Egyptian patients with BD and 87 healthy controls. Methodology: Blood samples were collected and DNA extraction done. Genotyping of TLR1 gene (1805 T/G), and TLR3 gene (1377 C/T) were performed using (PCR-RFLP) and we found In TLR1 gene (1805 T/G) • Patients with BD had significantly lower frequency of TT genotype and significantly higher frequency of TG , GG genotypes than healthy control • Patients with arthritis had significantly lower frequency of TT & TG, patients with activity had significantly lower frequency of GG genotype. • Patients with activity had significantly lower frequency of T allele, it might be protective allele and patients with arthritis had significantly lower frequency of G allele, it might be protective allele. In TLR3 gene (1377 C/T) • Patients with BD had significantly lower frequency of CC genotype and higher frequency of CT genotype than healthy control. • Patients with vascular involvement had significantly lower frequency of TT genotype. • BD patients with vascular involvement had significantly lower frequency of C allele than patients without involvement it might be protective allele. In conclusion, this preliminary study indicates that there are some genotypes in TLR1 gene (1805 T/G) ,and TLR3 gene (1377 C/T) over-represented , other less presented in BD indicating that they may play a role in BD susceptibility in Egyptian patients.
Der Projektauftraggeber. Leitfaden zur Governance für erfolgreiche Projekte
Authors: Atzor Michael , Boxheimer Michael , Hunziker Thomas , Ortner Gerhard , Rudischer Christian , Wenzler Hartmut
Published: September 2022

Für Projektleiter gibt es schon länger umfangreiche Aus- und Weiterbildungsprogramme. Das passt. Auch der Projektauftraggeber ist eminent wichtig für den Erfolg eines Projektes. Doch Auftraggeber zu sein bedeutet mehr als «fire and forget». Das Projekt muss auch nach der schriftlichen Auftragsvergabe intensiv begleitet werden. Das braucht Zeit und Engagement. Sei dies in einer 1:1 Situation mit dem Projektleiter oder als Leiter eines Lenkungsausschusses. Zur erfolgreichen Umsetzung gehört also auch ein angemessenes Projektmanagement-Know-how beim Senior Management, das kompakt vermittelt werden kann. In diesem Leitfaden zeigen wir auf, was ein guter Projektauftraggeber mitbringen sollte.
Commercial Project Management (CPM) aus Auftraggeber-Sicht
Authors: Oleniczak Gregor , Reschke Hasso
Published: September 2022

Commercial Project Management (CPM) ist ein unverzichtbarer Baustein im Projektmanagement geworden, vor allem bei größeren Auftragnehmern. Dabei werden alle nicht-technischen Aufgaben von der Projektentstehung über die Projektrealisierung bis hin zum Projektabschluss in einer Hand zusammengefasst. Für den Project Manager stehen meistens die technischen Aufgaben im Vordergrund. Aber auch im nicht-technischen Kontext steigt die Komplexität. Für eine erfolgreiche Projektarbeit müssen deshalb auch kaufmännische und vertragliche Aufgaben qualifiziert bearbeitet und erfüllt werden. Dies gilt insbesondere im internationalen Projektumfeld. Für den Auftraggeber sind als Pendant zum Auftragnehmer die kommerziellen Themen ähnlich wichtig, wenn auch aus einem anderen Blickwinkel. Auf der Auftraggeber-Seite werden große Infrastruktur- und Anlagenbauprojekte (z. B. Häfen, Energietrassen, Fertigungsanlagen) initiiert, geplant und realisiert. Für die Projektdurchführung müssen eine Reihe an Firmen mit der Realisierung beauftragt werden. Je nach Geschäftszweck, Betriebsgröße und speziellen Projektanforderungen ist das Aufgabenspektrum unterschiedlich stark ausgeprägt. Im Zuge der stetig wachsenden nicht-technischen Anforderungen an die Projekte ist eine Aufgabenteilung zwischen Projektmanager und dem Commercial Project Manager hilfreich/essenziell und Garant für erfolgreiche Projektarbeit. CPM muss sich auch in Deutschland weiter etablieren. Deshalb hat die CPM 2019 eine Fachgruppe gegründet. Diese beschäftigt sich mit der Weiterentwicklung des CPM. Ihre Mitglieder kommen aus der einschlägigen deutschen Industrie und Wirtschaft. Dort wurde u. a. ein englischsprachiger Zertifikatslehrgang für CPM entwickelt, der in diesem Jahr an der FOM-Hochschule in Siegen Premiere hat.
Was sollten Projektsponsor:innen über Projektdiagnosen wissen?
Authors: Lomnitz Gero
Published: September 2022

In diesem Beitrag wird erläutert, was Projektdiagnose bedeutet und welchen Nutzen Projektsponsoren von einer professionellen Diagnose haben. Review ist im Unterschied zur Diagnose ein sehr bekannter Begriff im Projektmanagement. In Reviews werden u. a. mangelnde Zielerreichung, Prioritätenprobleme, Budgetüberschreitungen, Informationsprobleme und auch die Zusammenarbeit im Team ermittelt. Der wesentliche Unterschied zur Projektdiagnose besteht darin, dass in Reviews selten die dahinterliegenden Kernursachen analysiert werden. Durch eine Projektdiagnose werden Interessenkonflikte, Machtprozesse, paradoxe Entscheidungen, Wiederholungsmuster oder verlagerte Probleme gezielt ermittelt. Die Leser erfahren, worauf Projektsponsoren vom Beginn bis zum Ende der Projektdiagnose achten sollten. Im Sinne der vereinfachten Lesbarkeit wurde mit Gender-Formen flexibel umgegangen.
Mythen über den Auftraggeber aus Sicht der PL
Authors: Lomnitz Gero
Published: September 2022

Enttäuschungen beruhen auf Täuschungen. Täuschungen entstehen durch Verhaltensweisen anderer, beispielsweise durch falsche Aussagen, leere Versprechungen, Lügen oder Intrigen. Doch Täuschungen werden auch durch Selbsttäuschungen verursacht, mit anderen Worten, man macht sich etwas vor, geht von unreflektierten Annahmen aus, der Wunsch ist die Mutter oder der Vater des Gedankens. Was bedeutet das für die Projektleitung und ihr Verhältnis zu Auftraggeberinnen und Auftraggeber? Lesen Sie weiter: Den idealen Auftraggeber, die ideale Auftraggeberin, welche Projektmanager:innen hätten so etwas nicht gerne? Im Idealfall vereinigen sich folgende Merkmale: Ausreichender Sachverstand (nicht zu verwechseln mit Detailkenntnissen), Interesse am Projekt, Entscheidungsbereitschaft und Durchsetzungsvermögen (sprich Macht) sowie Budget. Doch die Verhältnisse sind leider nicht immer so. Erstaunlicherweise gehen manche Projektmanager:innen davon aus, dass die Auftraggeber:innen dem Idealzustand mehr oder minder entsprechen. In der Praxis ist es empfehlenswert, sich von diesen Illusionen zu befreien. Wenn Sie weiter träumen wollen, dann können Ihnen die nachfolgenden Empfehlungen helfen.
Die hohe Kunst des Falschmachens. Mach bloß nicht alles, was Chef und Kunde verlangen!
Authors: Schmidt Patrick
Published: September 2022

Wer macht, macht Fehler – meist ohne Absicht, jedoch frei nach Shakespeare: Ist es auch Wahnsinn, so hat es doch Methode. Eine besonders perfide Methode sind „Die 4 Imperative des Falschmachens“. Erster: Mach am besten alles selbst! Wenn das Projektteam nicht liefern kann oder will. Anstatt MinderleisterInnen erst einmal dezidiert nach dem zu fragen, was sich aufhält oder schlicht zu insistieren. Zweiter: Mach alles, was Chef und Chefin wollen! Anstatt deren geniale Ideen zunächst auf den Backlog zu setzen oder auf den Hauptsatz des Agilen Projektmanagements zu verweisen. Dritter: Mach’s so wie immer! Anstatt alte Zöpfe abzuschneiden und rigide Regeln zu ignorieren, wofür es nur eine einzige Voraussetzung braucht. Und viertens: Mach, was die Kundschaft will! Anstatt zu dokumentieren und zu eskalieren.
FACE MASKS, BETWEEN SOCIAL AND POLITICAL MESSAGES IN COVID-19 PANDEMIC: A SEMIOTIC ANALYSIS
Authors: Dewi Octavia Chandra
Published: September 2022

In the COVID-19 pandemic, people should wear face masks as medical equipment to stop the spread of the coronavirus. Some people donate and distribute face masks to many other people in social charity events. Unfortunately, these kinds of events are used by some people to do political campaigns while distributing donations. This study conducted a Semiotic analysis to describe and analyze signifiers brought by face masks distributed in a social charity event by a Klaten’s regent that symbolizes social and political messages. Using the concept of ‘rhetoric of the image’ by Barthes (1977), which was dragged into a critical semiotics study, which analyzed the image, colors, and written language on the object observed in a video taken from television news. Political messages are often disguised in social events and publications to gain more supporters for bigger chances to win the election.
PENAMBAHAN FONEM VOKAL PADA GAIRAIGO DALAM LIRIK LAGU ALBUM “S. F. SOUND FURNITURE” KARYA CAPSULE
Authors: Aryanto Siti Shafa Febriani , Indrayani Lia Maulia , Sidiq Inu Isnaeni
Published: September 2022

Dalam bahasa Jepang, gairaigo merupakan kata serapan atau kata pinjaman dari bahasa asing. Ketika mengadaptasikan suatu kata atau istilah dari bahasa lain, maka kata tersebut harus disesuaikan dengan aturan-aturan yang terdapat pada bahasa Jepang, seperti pada aspek fonologisnya. Bahasa Inggris memiliki silabel terbuka dan tertutup, yang kemudian menjadi masalah jika kata yang terdiri dari silabel tertutup dipinjam oleh bahasa Jepang. Oleh karena itu, agar silabel tertutup dapat menjadi silabel terbuka, perlu ditambahkan fonem vokal tertentu pada silabel tertutup tersebut. Fonem-fonem ini adalah fonem /i/, /u/, dan /o/, sesuai dengan teori Kawarazaki (1989) dan teori Kubozono (2015). Penelitian ini bertujuan untuk mengidentifikasi proses penambahan fonem vokal yang terjadi pada gairaigo dalam album “S. F. sound furniture” karya duo musikus Jepang CAPSULE. Penelitian ini menggunakan metode kualitatif deskriptif. Hasil penelitian menunjukkan bahwa terdapat 19 data gairaigo dari album tersebut dan masing-masing 8 data mengalami penambahan fonem vokal di bagian tengah kata dan akhir kata.
BAHASA RASIS PEMIMPIN PERGURUAN TINGGI DALAM PARADIGMA HISTORIS EDDIE COLE
Authors: Gultom Andri Fransiskus
Published: September 2022

Penelitian ini bertujuan untuk mengungkap bahasa rasis dalam lingkup akademis. Bahasa rasis ditemukan dalam ungkapan atau ujaran dari para pemimpin perguruan tinggi untuk mendiskriminasi ras kulit hitam. Penelitian menggunakan metode kualitatif dengan paradigma historis resistensi di kampus-kampus di Amerika Serikat. Beberapa metode yang digunakan: verstehen atau pembacaan teks dengan memahami terlebih dahulu data primer. deksripsi komparatif pada isu rasisme dalam konteks Indonesia. Untuk itu, penulis juga melakukan interpretasi yakni menafsirkan problem bahasa rasis dengan memahami situasi akademis di Indonesia dan memberi solusi. Temuan penelitian yaitu pertama, pemimpin perguruan tinggi adalah administrator pengambil kebijakan penting yang diharapkan untuk berbicara kepada publik ketika rasisme terjadi di kampus-kampus, namun sebagian dari mereka menyampaikan ujaran rasis. Kedua, bahasa rasis terungkap secara implisit dan eksplisit di universitas dalam beragam kebijakan, mulai dari saat pendaftaran, diskriminasi perumahan mahasiswa kulit hitam, sistem birokrasi perguruan tinggi yang berubah, konflik administrasi kampus, segregrasi, kekerasan di kampus dan problem hak-hak sipil. Rekomendasi penelitian bahwa affirmative action perlu dijalankan dalam bentuk komunikasi dan transformasi di perguruan tinggi.