bluuebunny/crossref_metadata_2025 huggingface dataset:
Structural basis of nucleosomal histone H4 lysine 20 methylation by SET8 methyltransferase
Authors: Ho Cheng-Han , Takizawa Yoshimasa , Kobayashi Wataru , Arimura Yasuhiro , Kimura Hiroshi , Kurumizaka Hitoshi
Published: February 2021

SET8 is solely responsible for histone H4 lysine-20 (H4K20) monomethylation, which preferentially occurs in nucleosomal H4. However, the underlying mechanism by which SET8 specifically promotes the H4K20 monomethylation in the nucleosome has not been elucidated. Here, we report the cryo-EM structures of the human SET8–nucleosome complexes with histone H3 and the centromeric H3 variant, CENP-A. Surprisingly, we found that the overall cryo-EM structures of the SET8–nucleosome complexes are substantially different from the previous crystal structure models. In the complexes with H3 and CENP-A nucleosomes, SET8 specifically binds the nucleosomal acidic patch via an arginine anchor, composed of the Arg188 and Arg192 residues. Mutational analyses revealed that the interaction between the SET8 arginine anchor and the nucleosomal acidic patch plays an essential role in the H4K20 monomethylation activity. These results provide the groundwork for understanding the mechanism by which SET8 specifically accomplishes the H4K20 monomethylation in the nucleosome.
Business security management in modern conditions
Authors: Shumilina Vera , Kleptsov Vadim , Grushina Viktoria , Krohicheva Galina , Popova Anastasia , Ovchinnikova Liubov , Boguslav Ekaterina , Poluyan Vlada , Storozhenko yuliana , Talanina Veronika , Borzykh Anastasiaya , Bokova Amina , Kryukov Rodion , Mezentseva Yuliya , Bidgiev Zamir , Tetunashvili Elena , Ogandzhanyan Diana , Klimina Ksenia , Omelchenko Alexsandra , Gorodinskaya Irina , Varchenko Anna , Tepegendjiyan Anguelina , Filev Dmitriy , Yunkina Irina , Nikitin Sergey , Pilyuk Darya , Shichanin Aleksandr , Murza Bogdan , Izvarina Nataliya , Sokolova Al'bina , Chernyshov Ilia
Published: February 2021

The modern economy is characterized by a high level of dynamism of the factors of the external and internal environment of enterprises, influencing the possibility of their stable development.
With the transition of the Russian economy to market methods of doing business, in which enterprise management must take into account various scenarios, risk becomes an integral element of socio-economic relations. Risk is present in all spheres of life, regardless of whether its presence is taken into account in the situation of choosing an alternative method of managing a business entity or not. The presence of risk is a significant factor in the development of business and the economy as a whole. To minimize and neutralize risks, the enterprise must constantly ensure its safety.
In modern conditions, due to the pandemic and economic downturn, enterprises are forced to revise their methods of safety management and risk neutralization.
This monograph, dedicated to modern problems of business security management, is the result of the joint work of teachers and students of the Department of Economic Security, Accounting and Law of the Don State Technical University.
ECONOMIC RISKS AND THREATS TO BUSINESS SECURITY
Authors: Shumilina Vera , Popova Anastasia , Ovchinnikova Liubov
Published: February 2021

This article is devoted to economic risks and threats to business security. Special attention is paid to the causes of various risks and threats in business, the source of their occurrence, and the classification of threats
ANALYSIS AND ASSESSMENT OF RISKS FOR ENSURING ECONOMIC SECURITY
Authors: Shumilina Vera , Boguslav Ekaterina
Published: February 2021

The article discusses one of the most important areas of activity of an enterprise or the country as a whole, namely, ensuring economic security, the risks to which it is exposed and the assessments with which it is analyzed. This topic is relevant, since in any unstable situation, the economy suffers first of all. The purpose and methodology of risk analysis, indicators and criteria of economic security, as well as its assessment are highlighted. It is especially important to pay attention to the solution of problems in the process of analysis and its implementation, because effective provision of economic security depends on this.
Essence, goals, basic principles and functions of marketing
Authors: Shumilina Vera , Omelchenko Alexsandra , Gorodinskaya Irina
Published: February 2021

This article discusses the problems of cost management faced by enterprises in modern conditions and ways to solve them in order to improve economic results. The goals, objectives, and methods of cost management are presented.
Economic and legal support for the activities of an economic entity in the context of a pandemic
Authors: Shumilina Vera , Murza Bogdan , Shichanin Aleksandr
Published: February 2021

current problems are the instability of the regulatory framework; monopolism of large companies and suppression of small businesses; economic crime and corruption; insufficient number of qualified specialists of higher and middle management of enterprises, including security managers; low level of reliability of performance of contractual obligations; illegal activities of competitors, etc. In this regard, the majority of Russian entrepreneurs, scientists and practitioners face an urgent problem of legal support for business activities, finding ways to solve the problems of reliable protection of the legitimate interests and rights of economic entities
BANKRUPTCY IN SMALL BUSINESS IN CONNECTION WITH THE PANDEMIC
Authors: Shumilina Vera , Nikitin Sergey
Published: February 2021

The coronavirus pandemic has had serious economic consequences. As a result, the demand for consumer goods and services has fallen sharply, and the service sector is suffering huge losses. Accordingly, revenue also fell, while the mandatory costs remained unchanged: loan payments, rent payments, salaries, taxes and social contributions. The resulting cash gap is likely to lead to massive bankruptcies.
Controle de nabo e azevém em trigo com herbicidas pós-emergentes
Authors: Balem Rudinei , Rodrigues Padilha Lucimara , Michelon Cleudson José , Costa Leandro
Published: February 2021

A coexistência de plantas daninhas nos estádios inicias de desenvolvimentos na cultura de trigo, reduzem o potencial produtivo da cultura refletindo no menor rendimento de grãos. Nesse sentido, o objetivo do presente trabalho foi avaliar o controle de Azevém (Lolium multiflorum) e nabo (Raphanus raphanistrum L.) com a utilização de herbicidas aplicados em pós-emergência em duas cultivares de trigo, além de mensurar o efeito fitotóxico dos herbicidas sobre a cultura. O experimento teve os seguintes tratamentos: Clodinafope - propargil, Pinoxadene, Iodosulfurom hoefix e Pyroxsulam, nas dosagens recomendadas pelo fabricante, 25% a menos e 25% a mais da dose recomendada. A aplicação dos herbicidas ocorreu no estádio de perfilhamento do trigo, com pulverizador de pressão (CO2), pontas tipo jato leque plano simples, da série 11002, com vazão de 150 L ha-1. As avaliações foram realizadas aos 7, 14, 21 e 28 dias após aplicação (DAA), emitindo uma nota de fitotoxidade, sendo 0 com ausência de fitotoxidade e 100 com a máxima fitotoxidade (morte de planta). Os resultados obtidos foram submetidos à análise de variância e as médias comparadas pelo teste de tukey a 5% de significância. A fitotoxidade foi notória apenas nos 7 DAA. O herbicida Pinoxadene apresentou o melhor controle de azevém e foi o tratamento em que a cultura do trigo apresentou o maior rendimento de grãos. O percentual de fitotoxidez foi estável entre cultivares, sendo a característica de fitotoxidez atrelada a produtos.
Los warao del Delta del Orinoco: aspectos de su cosmogonía, etnografía y situación actual
Authors: González Ñáñez Omar Enrique
Published: February 2021

El presente artículo ofrece una visión etnográfica del pueblo amerindio warao, una sociedad lingüísticamente independiente de aproximadamente 30.088 individuos (año 2011) que viven en el estuario del Delta del Orinoco, ubicado al noroeste de Venezuela, lugar donde dicho río desemboca en el Océano Atlántico, estando, además, muy próximo a la República de Trinidad y Tobago. En el texto se destaca aspectos mostrados por la etnografía tradicional respecto a la cultura warao, su importante cosmogonía, cosmología y algunos pasajes de su etnohistoria y mitología. Son mencionados también ciertos aspectos de salud, alimentación, economía y situaciones actuales sobre migración y éxodo de su hábitat no solo hacia el centro de Venezuela, sino a otros lugares como Guyana y Brasil.
Atos de resistência e organização de povos indígenas na Amazônia venezuelana face aos novos empreendimentos econômicos
Authors: Acevedo Marin Rosa Elizabeth
Published: February 2021

Refletir sobre o Território de povos indígenas na Amazônia Venezuelana face aos novos empreendimentos econômicos (2017) foi o objetivo do “ensaio memorialístico” apresentado como requisito para a Progressão Funcional para o cargo de Professor Titular na Universidade Federal do Pará. Nas três últimas décadas, a luta dos movimentos sociais pela apropriação coletiva da terra encontra obstáculos nos Estados Nacionais e nos aparatos coloniais nessa região subcontinental. Por que e de que forma se erigem esses obstáculos em cada realidade específica e quais são as barreiras comuns? Essa questão tem centralidade nas investigações e é fundamental na agenda política geral do subcontinente, qualquer que seja o interessado - os movimentos sociais, as agências da política estatal ou a acadêmica. O desejo e a necessidade intelectual de refletir sobre essas questões inscrevem-se na minha experiência de vida e trajetória acadêmica. Por mais de quatro décadas tenho vivido e trabalhado na Amazônia brasileira e empreendido pesquisas sobre as questões de terra na Pan-Amazônia, especialmente em Venezuela, Colômbia, Bolívia, Equador, Guiana Francesa e Brasil. Neste trabalho retornei ao ensaio memorialístico e destaquei o que tem sido os atos de resistência e organização de Povos Indígenas na Amazônia Venezuelana face aos novos empreendimentos econômicos.
METODE SERVQUAL, KUADRAN IPA, DAN INDEKS PGCV UNTUK MENGANALISIS KUALITAS PELAYANAN RUMAH SAKIT X
Authors: Alifah Ulfi Nur , Prahutama Alan , Rusgiyono Agus
Published: February 2021

The quality of service provided by the hospital is very important because it can be used as a reference in determining customer satisfaction. Service quality can be perceived as good and successful if the customer is satisfied with the services and suitable with what customers expect. However, if the services are not suitable with customer expectations, the service quality will be perceived as bad. This study aims to analyze the service quality of X Hospital based on five dimensions of service quality. The data was collected by distributing questionnaires to 64 selected respondents who were patients from Hospital X. Then, the data were calculated the value of the gap between customer expectations and perceptions. Then analyzed using the Importance Performance Analysis method and the Potential Gain Customer Value Index to determine the priority of service quality improvement. Based on the research results, there are only 5 indicators that have a positive gap score, which means that the service quality is suitable with customer expectations. From the Importance Performance Analysis quadrant, the indicators of service quality are spread across four quadrants. From the PGCV index, the indicator of service quality that becomes the first priority for improvement is the ease of access to purchase necessities for patients.
PENERAPAN JARINGAN SARAF TIRUAN PADA DATA GEMPA BUMI DI PROVINSI BENGKULU
Authors: Agwil Winalia
Published: February 2021

Provinsi Bengkulu merupakan wilayah yang sangat dekat dengan subduksi lempeng Eurasia dan Indo-Australia, hal ini mengakibatkan provinsi Bengkulu menjadi daerah yang rawan terjadinya bencana gempa bumi. Prediksi mengenai banyak kejadian dan rata-rata magnitudo gempa sangat menarik untuk di teliti. Penelitian mengenai analisis gempa bumi telah banyak dilakukan salah satunya dengan metode data mining yaitu Jaringan Saraf Tiruan. Tujuan dari penelitian ini adalah memperoleh arsitektur jaringan terbaik yang diterapkan pada data frekuensi kejadian dan rata-rata magnitudo gempa bumi per bulan di Provinsi Bengkulu. Kriteria pemilihan arsitektur jaringan terbaik dilakukan dengan membandingkan nilai RMSE dan MAE setiap kemungkinan arsitektur yang terbentuk. Hasil prediksi rata-rata magnitudo per bulan yang dimodelkan dengan arsitektur 1-3-1 lebih baik dibandingkan dengan arsitektur 12-3-1.
PERAMALAN INFLOW UANG KARTAL BANK INDONESIA KPW TASIKMALAYA JAWA BARAT DENGAN METODE KLASIK DAN MODERN
Authors: Rahmi Nur Silviyah
Published: February 2021

Ketersediaan uang kartal di Bank Indonesia (BI) dapat ditinjau melalui arus keluar masuknya uang kartal yang disebut dengan istilah inflow. Banyaknya uang yang beredar di masyarakat akan berpengaruh pada kondisi perekonomian suatu negara, sehingga Bank Indonesia (BI) menyusun perencanaan kebutuhan uang rupiah. Penelitian ini bertujuan untuk meramalkan inflow uang kartal di KPw Bank Indonesia (BI) Tasikmalaya dengan menggunakan pemodelan ARIMA, ARIMAX, Metode Dekomposisi, Metode Winter’s, MLP (Multilayer Perceptron) atau FFNN (Feed Forward Neural Network), Regresi Time Series, Metode Naïve dan Model Hybrid. Dari delapan metode runtun waktu tersebut baik klasik maupun modern akan dicari metode mana yang memberikan hasil akurasi ramalan yang terbaik dengan kriteria RMSE, MAPE dan MAD. Kesimpulan yang dihasilkan yaitu Hybrid ARIMA-NN yang merupakan gabungan dari model ARIMA dengan neural network tidak menjamin kinerja hasil peramalan yang lebih baik. Seperti yang disebutkan dalam hasil M3 Competition, semakin kompleks metode yang digunakan belum tentu metode tersebut menghasilkan akurasi yang lebih baik dibandingkan metode sederhana (klasik). Pada ramalan data inflow KPw BI Tasikmalaya Jawa Barat ini, menghasilkan kesimpulan bahwa metode regresi time series memiliki nilai kriteria pemodelan paling kecil dibandingkan dengan metode lainnya.
KLASIFIKASI TINGKAT KELANCARAN NASABAH DALAM MEMBAYAR PREMI DENGAN MENGGUNAKAN METODE K-NEAREST NEIGHBOR DAN ANALISIS DISKRIMINAN FISHER (Studi kasus: Data Nasabah PT. Prudential Life Samarinda Tahun 2019)
Authors: Saeroni Amanah , Hayati Memi Nor , Goejantoro Rito
Published: February 2021

Classification is a technique to form a model of data that is already known to its classification group. The model that was formed will be used to classify new objects. The K-Nearest Neighbor (K-NN) algorithm is a method for classifying new objects based on their K nearest neighbor. Fisher discriminant analysis is a multivariate technique for separating objects in different groups to form a discriminant function for allocate new objects in groups. This research has a goal to determine the results of classifying customer premium payment status using the K-NN method and Fisher discriminant analysis and comparing the accuracy of the K-NN method classification and Fisher discriminant analysis on the insurance customer premium payment status. The data used is the insurance customer data of PT. Prudential Life Samarinda in 2019 with current premium payment status or non-current premium payment status and four independent variables are age, duration of premium payment, income and premium payment amount. The results of the comparative measurement of accuracy from the two analyzes show that the K-NN method has a higher level of accuracy than Fisher discriminant analysis for the classification of insurance customers premium payment status. The results of misclassification using the APER (Apparent Error Rate) in K-NN method is 15% while in Fisher discriminant analysis is 30%.
The Development of Instructional Leadership Scale of Elementary School Principals in Indonesia
Authors: Widiyan Agung Purwa , Sirisooksilp Saowanee , Narot Pennee Kantavong
Published: February 2021

This research aims to develop a scale to measure the practice of instructional leadership of elementary school principals in Indonesia. A sequential mixed-methods approach was chosen involving 238 school principals at public elementary schools in Bogor regency, Indonesia. The new instructional leadership scale showed appropriate levels of reliability and validity. The reliability of the developed scale was 0,875. The construct validity was examined; second-ordered confirmatory factor analysis was at a satisfactory level, Chi-square χ2=434.489, CFI =.934, p=.113, TLI=.928, RMSEA=.019, SRMR=.046. Convergent and discriminant validity were at an acceptable level as well. Qualitative results concluded that there were three identities of instructional leadership: instructional knowledge, attitude, and skills. By providing a new scale to measure instructional leadership roles, it could help navigate effectively that the roles of school leaders for learning reforms.
Unlocking the Cultural Diversity Black Box: Application of Culturally Responsive Pedagogies in University Classrooms in Zimbabwe
Authors: Rudhumbu Norman
Published: February 2021

The study investigated the mediating role of lecturers’ biographic factors and multicultural competences in the use of Culturally Responsive Pedagogies (CRPs) to effectively teach culturally diverse classrooms in universities. Studies show that culture has an influence on student learning and that if it is not effectively managed, it can affect how students learn. The study employed a quantitative approach that used structured questionnaires for data collection from a sample of 370 lecturers selected from six universities using a stratified random sampling strategy. Principal Component Analysis (PCA) was used for data purification. Data were analyzed using descriptive statistics, One-way ANOVA, multiple regression analysis, and correlation analysis. Results showed that verbal and non-verbal communication, cultural knowledge, classroom management, and student-teacher interaction significantly influenced the application of CRPs by university lecturers. It also emerged from the study that the application of CRPs has a significant effect on diversity management in universities. Results further showed that the use of CRPs by university lecturers is still work in progress due to a myriad of challenges they face chief among which is a lack of cultural competence skills. These results have implications to diversity management in university classrooms in particular as well as in universities in general.
A Conceptual Research Model for Investigating the Impact of Online Teacherpreneurship Education on Students’ Teacherpreneurial Competencies and Intentions in Preservice Teacher Education
Authors: Lasekan Olusiji Adebola , Malik Reyaz , Alarcon Claudia Méndez
Published: February 2021

This article seeks to develop a research model that can be employed to study the impact of online teacherpreneurship education on students' teacherpreneurial competence and intention as well as employability. Based on the redefinition of the role of online teacherpreneur as an online private tutor, instructional designer, entrepreneur, and teacher leader, a qualitative literature review of competencies for these roles was conducted. We merged the identified competencies according to conceptual similarities. Our result is an online teacherpreneurship competency adopted to formulate a research model which is a customized measuring instrument for investigating the effect of online teacherpreneurship training on preservice teachers’ teacherpreneurial competencies and intentions. This finding has important implications for developing a template for students, policymakers, and teacher educators needed to create online teacherpreneurship courses, curricula, and evaluations.
Produção, validação e avaliação de um jogo didático sobre o tema Corpo Humano para o Ensino Médio Regular
Authors: Costa Rosa Cristina , Miranda Jean Carlos
Published: February 2021

Partindo do pressuposto que quando o discente tem prazer nas atividades realizadas, a aprendizagem torna-se mais atrativa e significativa, motivando-o na construção do conhecimento e sendo protagonista de sua trajetória acadêmica, e sabendo que diversos autores ressaltam a influência positiva do uso de jogos didáticos no processo ensino-aprendizagem,  o presente trabalho objetivou a produção, a validação e a avaliação de um jogo didático como ferramenta auxiliar na abordagem de conteúdos sobre o tema Corpo Humano. O jogo didático foi aplicado aos discentes do Ensino Médio do Colégio Estadual Rui Guimarães de Almeida, no município de Santo Antônio de Pádua-RJ. A validação do jogo foi feita por meio da aplicação de dois questionários (de sondagem do conhecimento e de verificação de aprendizagem). A avaliação da funcionalidade técnica do jogo foi realizada por meio da aplicação do questionário de usabilidade.  Os resultados obtidos indicam que o jogo didático “Viagem Pelo Corpo Humano” atingiu o seu objetivo didático-pedagógico, de forma que pode ser considerado apropriado como ferramenta que contribui no processo de aquisição do conhecimento.
RESEARCH ON CULTIVATION OF TAX RISK CONTROL ABILITY UNDER THE BACKGROUND OF INDUSTRY AND EDUCATION INTEGRATION
Authors: Ji Zhu , Lin Li-Wei
Published: February 2021

The goal of professional application-oriented construction is to improve students' practical application ability. Under the background of the integration of industry and education, the core ability of taxation major should be highlighted and cultivated is tax risk control ability. Such management ability is increasingly expected by the society among various abilities possessed by professional graduates. The author combined with the professional construction of the working university, from the content design, progress, training experience, optimization and improvement of professional core competence training to explore beneficial, to provide policy optimization suggestions for the cultivation of tax risk management talents.
Muğla ili Menteşe yöresi orman yangını risk potansiyeli haritasının coğrafi bilgi sistemleri ile belirlenmesi
Authors: ALKAYIŞ Mehmet Hanifi , KARSLIOĞLU Asena , ONUR Mehmet İnanç
Published: February 2021

Orman yangınları, farklı sebeplerle başlayıp geniş alanlara yayılabilen büyük bir çevre felaketidir. Ülkemizde Akdeniz ve Ege bölgeleri, başta olmak üzere yaklaşık 12 milyon hektar ormanlık alan yangın konusunda potansiyel risk taşımaktadır. Orman yangını risk bölgeleri, yangının kolayca başlayabileceği ve diğer alanlara hızlıca yayılabileceği yerler olarak bilinmektedir. Doğayı kontrol etmek imkânsızdır, fakat orman yangını risk bölgelerini haritalayarak yangın yayılımını en aza indirmek ve hasarı azaltmak mümkündür. Orman Genel Müdürlüğü’nün 2018 yılı verilerine göre ülkemizde toplam 2167 adet orman yangını olduğu ve 299 adet orman yangınıyla Muğla ilinin 1.sırada olduğu görülmektedir. Menteşe, Kavaklıdere, Ula, Yatağan, Milas, Marmaris, Datça ve Bodrum ilçelerini kapsayan Menteşe yöresinde ise bu yangınların yaklaşık yarısı gerçekleşmiştir. Bu çalışmanın amacı Muğla ili Menteşe yöresinin yangın risk haritasının hazırlanmasıdır. Çalışma için yola ve yerleşime olan uzaklık, bakı, eğim ve vejetasyon temel parametreler olarak belirlenmiştir. Çalışma sonucunda Coğrafi Bilgi Sistemleri (CBS) tabanlı orman yangını risk haritası hazırlanmıştır. Yangın risk haritasına göre; alanın %11,86’sı yüksek riskli, %18,32’si riskli, %25,23’ü orta riskli, %20,40’ı düşük riskli, %24,19’u ise risksizdir. Çalışma sonuçlarının orman yangınlarına karşı planlama, tedbir ve yönetim çalışmalarında yol gösterici olacağı düşünülmektedir.
Güneş enerjisi santral (GES) yapım yerlerinin CBS dayalı çok kriterli karar analizi ile belirlenmesi: Karabük örneği
Authors: ARCA Deniz , KESKİN ÇITIROĞLU Hülya
Published: February 2021

Günümüzün globalleşen dünyasında insanoğlunun temel ihtiyaçlarından biri olan enerji, teknolojinin ilerlemesi ile daha da önem kazanmıştır. Geleneksel yöntemler ile enerji üretimindeki sınırlamalar ve çevresel kaygılar neticesinde, yenilenebilir enerjiye doğru hızlı bir yönelim gerçekleşmektedir. Yenilenebilir enerji santrallerinin kurulumu ve işletme esnasındaki verimliliği açısından, yerlerinin seçimi büyük önem taşımaktadır. Güneş enerjisi, günümüzde hayatımızın önemli ve kaçınılmaz bir parçası haline gelmiş olan sürdürülebilir ve yenilenebilir enerji kaynakları arasında yer almaktadır. Güneş enerji santrallerin (GES) kurulum yerlerinin belirlenmesinde ekonomik, çevresel ve sosyal faktörlerin dikkate alınması oldukça büyük önem arz etmektedir. Bu çalışmanın amacı Karabük ilinde GES kurulabilecek en uygun alanların Coğrafi Bilgi Sistemleri (CBS) ve Çok Kriterli Karar Verme (ÇKKA) yöntemlerinden biri olan Analitik Hiyerarşi Yöntemi (AHY) kullanılarak belirlenmesidir. Elde edilen sonuçlara göre, çalışma alanının GES yapımı için orta ve düşük duyarlılık düzeyinde olduğu tespit edilmiştir.
Utilização das folhas de comigo-ninguém-pode (Dieffenbachia seguine) como bioadsorvente para a remoção de íons metálicos
Authors: Sousa Francivaldo de , Sousa José Sérgio de , Silva Afranio Gabriel da , Marques Diego Isaias Dias , Quirino Max Rocha , Lucena Guilherme Leocárdio
Published: February 2021

A presença de metais pesados pode tornar-se motivo de preocupação em função da possibilidade de movimentação e consequente contaminação de camadas superficiais do solo e águas subterrâneas, comprometendo a saúde de plantas e animais. Dentre os métodos de descontaminação, a bioadsorção tem apresentando bons resultados econômicos e ecológicos. Neste trabalho, folhas da planta comigo-ninguém-pode (CNP) foram utilizadas na remoção de íons Cu2+ de soluções aquosas. Realizou-se a desidratação das folhas da planta em estufa, até massa constante, em seguida procedeu as etapas de pulverização e peneiramento.  Os ensaios de adsorção foram realizados em batelada, sendo composto por 0.5 g das folhas desidratas com 100 mL de soluções aquosas de CuSO4 com diferentes concentrações. Uma avaliação do teor de íons oxalatos presentes nas folhas foi realizada pela técnica de permanganimetria. A caracterização e quantificação foi realizada pelas técnicas de difração de raios-X e espectroscopia de absorção atômica. Os resultados dos ensaios de adsorção mostraram que as folhas de CNP apresentaram 93% de remoção de Cu2+ quando testados em uma solução cuja concentração do metal foi de 600 mg L-1. Os difratogramas de raios-X confirmaram que o metal adsorvido incorporou na estrutura das folhas. O estudo cinético mostrou que a adsorção de Cu2+ pelas folhas de CNP obedecem ao modelo matemático de pseudossegunda ordem. O bioadsorvente testado neste trabalho apresentou elevada eficiência na descontaminação de efluentes contendo íons Cu2+. A utilização do processo utilizado propõe um mecanismo de descontaminação eficiente, de baixo custo e elevado valor ecológico, além de promover uma funcionalidade a uma espécie de planta tóxica.

Palavras chave: Bioadsorção, oxalatos, cinética.
The role of water-drive systems of ancient sedimentary basins in the processes of oil and gas accumulation
Authors: Abukova L.A. , Seliverstova M.E. , Isaeva G.Yu.
Published: February 2021

The article presents the authors’ ideas about the role of post-expulsion water-drive systems in localization of hydrocarbon deposits. It substantiates the key factors of hydrodynamic stagnation, which is a characteristic feature of the large depths of ancient sedimentary basins; it reveals that, within their bounds, in conditions of regional reservoir pressure deficiency the formation of synclinal hydrocarbon deposits is possible, and under ultra-high reservoir pressure – that of zones of oil and gas accumulation of autoclave type, within which the hydrogenation of mixed humus–sapropel organic matter is viable.
Technical and economic assessment of the efficiency of innovative digital technologies for preventing complications and accidents during oil and gas well construction: the case of the Musyurshorskoye field
Authors: Bogatkina Yu.G. , Sardanashvili O.N. , Nasekin K.K.
Published: February 2021

In 2019–2020, at the Oil and Gas Research Institute of the Russian Academy of Sciences, an automated system for preventing complications and accidents during oil and gas well construction was developed, which constitutes an integral part of the digital field. The article shows by the case of the Musyurshorskoye field that the use of the system allows to significantly increase the technical and economic efficiency of the development of hydrocarbon reserves. To assess it, two methods have been used based on different efficiency criteria: the total unit cost of liquidation of accidents and complications and the maximum profitable reserves per well. The methods are easy to use and speed up the process of making expert conclusions significantly.
Farber disease: A Fatal Childhood Disorder with Nervous System Involvement
Authors: Kraoua Ichraf , Ben Younes Thouraya , Garcia Virginie , Benrhouma Hanene , Klaa Hedia , Rouissi Aida , Levade Thierry , Youssef-Turki Ilhem Ben
Published: February 2021

Farber Disease is an autosomal recessive inherited lysosomal storage disorder which is characterized by tissue accumulation of ceramide. It is caused by mutations within ASAH1 encoding for acid ceramidase. It represents a rare condition. Only twenty seven cases have been reported. Seven subtypes of Farber disease have been identified. The clinical presentation is characterized by the appearance of subcutaneous skin nodules, bone and joint deformities, and progressive hoarseness. Neurological symptoms as psychomotor delay or regression, hypotonia, seizures, and peripheral neuropathy were reported in some subtypes of Farber disease. The nervous system involvement is correlated to poor prognosis. In this study, we report on clinical, biochemical and molecular findings of two Tunisian siblings with Farber disease.
The Role of TET Proteins in B Cell Biology
Authors: Tanaka Shinya , Ise Wataru , Baba Yoshihiro , Kurosaki Tomohiro
Published: February 2021

Gene expression must be strictly controlled during cell differentiation and function in mammalian systems. DNA methylation plays an important role in this process, and its pattern is shaped by balancing the activity of methyltransferases and demethylases. Ten-eleven translocation (TET) was identified as a demethylase that catalyzes the oxidation reaction of the methyl group of 5-methylcytosine (5mC), converting it to 5-hydroxymethylcytosine (5hmC). Recently, indispensable roles of TET proteins in the regulation of immune cells have been identified. Here, we review recent studies on the biological consequences of dysregulation of TET proteins in the immune system, with a particular focus on B cell biology. Finally, we discuss future perspectives in this research field.
Direito, narrativa e imaginário social
Authors: Karam Henriete , Castro Rosa Lima de Araújo
Published: February 2021

Este trabalho, que se insere no campo dos estudos em direito e literatura, tem como objetivo investigar em que medida a representação do feminino nas narrativas produzidas pela coletividade e instituídas em seu imaginário social podem legitimar a violência contra a mulher e, como consequência, colaborar para a ineficácia da aplicação da lei penal vigente no ordenamento brasileiro. Parte-se dos pressupostos oferecidos pelo campo do Direito e Literatura para examinar questões teóricas atinentes à representação do feminino e ao imaginário social. Na sequência, é apresentado o estudo de um caso que foi realizado: são analisadas as diferentes versões da história de Leocádia – narrativa mítico-fundacional da cidade de Guanambi –; discutidos os dados obtidos no levantamento do número de homicídios cometidos no município em 2014 e dos júris, a eles correspondentes, que já ocorreram; e, por fim, com base em tais dados, avaliada a eficácia do direito na proteção à mulher. Tal percurso permite concluir que a inefetividade da aplicação da lei penal na proteção à mulher vincula-se à ausência de prestação jurisdicional e à violência justificada pela culpabilização da vítima, resultando na impunidade do agressor.
PENGUKURAN LAJU ALIRAN UDARA DALAM PIPA SECARA SIMULTAN DENGAN TRANSDUSER GANDA ULTRASONIK
Authors: Wiranata Lalu Febrian
Published: February 2021

This paper aims to modification the transducer ultrasonic for measuring the distance to develop measure time of flight in the pipe with simultaneous method. To implement the application, we try to develop the microcontroller with one command transmitter and one command receiver in the same time, different from the conventional way, the transmitter and receiver work with consecutively. We try to reduce the delay time in two different transducers. In industrial, the symmetries profile must be ensured the profile always laminar. In this research, we try to use one path configuration. The result with the reference hot wire, we got the 27.76 percentage the difference of result. This is because the hot wire can measure the one path of flow in the one way of dot point.
POTENSI MADU SEBAGAI TERAPI TOPIKAL OTITIS EKSTERNA
Authors:   Departemen/ SMF Ilmu Kesehatan Telinga Hidung Tenggorok, Bedah Kepala dan Leher Fakultas Kedokteran Universitas Airlangga-RSUD Dr. Soetomo Surabaya, Sucipta Ibnu Yunis
Published: February 2021

Otitis externa (OE) is an external microbial Meatus acousticus (MAE) infection due to damage to the normal MAE serumen skin coat that protects and maintains MAE moisture and temperature. Living in the warm and humid tropics, a decrease in skin pH due to activity in the water including swimming, and excess cerumen cleaning are predisposing factors for OE. The use of antibiotics locally concentrated in OE can not only attack pathogenic microbes but also have an impact on normal flora so that it has the potential to cause resistant microbes. Honey has anti-bacterial properties without the risk of resistance and has even been shown to modulate immunity and inflammation. Various invivo and invitro studies prove that honey has broad spectrum anti-bacterial activity. Honey is proven invitro to modulate immunity by affecting the release of various inflammatory cytokines. This shows that honey has the potential for OE therapy. This article aims to discuss the potential of honey as a topical OE therapy in the hope that it can be an alternative choice of therapy in the management of OE in humans that is safe, effective, and efficient.
TRAUMA KEPALA PADA ANAK: KLASIFIKASI HINGGA PEMANTAUAN JANGKA PANJANG
Authors:   Pediatric department of medical faculty Wijaya Kusuma University Surabaya, Erny Erny , Prasetyo Okky ,   Fakultas Kedokteran Universitas Ciputra, Prasetyo Denny ,   Rumah Sakit Umum Muhammadiyah Gresik
Published: February 2021

Head trauma in children are frequent caused by falling, games, traffic accidents and more. Not all of head trauma continues to be brain injury. According with this, all of doctor must be able to established the diagnosis and classified head trauma to determine the optimal management and prognosis especially related with problems of brain development after head trauma. Long-term follow up should be done especially in severe and moderate head trauma to early detection any problems about development progress in this child
Ältere Patienten in Psychosomatischen Kliniken
Authors: Peters Meinolf
Published: February 2021

Die Behandlung älterer Patienten in Psychosomatischen Kliniken begann Anfang der 1990er Jahre. Die Behandlungszahlen sind bis heute nur allmählich angestiegen, dabei werden bevorzugt die »jungen Alten« behandelt, Hochaltrige hingegen nur selten stationär aufgenommen.
Análisis de las minas de agua de los Montes de Málaga mediante criterios de carácter patrimonial
Authors: Blanco Sepúlveda y Antonio Vela Torres Rafael
Published: February 2021

La histórica actividad agrícola de los Montes de Málaga (Málaga) generó un rico patrimonio de carácter hidráulico. El inventario realizado, sobre una muestra de 100 fincas, contiene 174 puntos de abastecimiento de agua, de los que el 92% corresponden a fuentes subterráneas, siendo las minas de agua las principales fuentes de abastecimiento, con el 44,83% de la muestra. Éstas, forman parte de una particular estrategia de abastecimiento de agua que no generó un extenso paisaje irrigado, circunstancia que dificulta la aplicación de los métodos tradicionales de valoración patrimonial basados en el paisaje (paisaje cultural de la UNESCO y sus variantes). El objetivo de este trabajo ha sido analizar las minas de agua mediante criterios de carácter patrimonial, lo que puede servir de base para justificar la incorporación de estos bienes en futuras ampliaciones de los inventarios patrimoniales del espacio rural del municipio de Málaga. El estudio que se ha realizado ha consistido en un análisis de los contextos geográfico e histórico del fenómeno hidráulico del área de estudio, para explicar el predominio de las minas de agua como fuentes de abastecimiento; y, finalmente, se ha realizado una clasificación tipológica y un análisis de las características constructivas de las mismas.
Censo y RPC-Venezuela: Dos Sistemas de Identificación paralelos para la protección legal del Patrimonio Cultural venezolano
Authors: Molina Calderón Cristina
Published: February 2021

El Censo del Patrimonio Cultural y el RPC son los dos Sistemas de Identificación y Registro que Venezuela ha implementado para proteger su Patrimonio Cultural, coexistiendo ambos instrumentos para el reconocimiento, catalogación y sobre todo la protección legal de los bienes tutelados por el Estado una vez que adquieren esta cualidad. De su aplicabilidad se demuestra que cerca de constituir un registro único para la efectiva protección de los bienes patrimoniales, ha generado una dualidad desde el ámbito jurídico que no ha quedado esclarecida bajo ningún instrumento o proceso administrativo. El presente artículo analiza de cerca la composición metodológica y la incidencia jurídica de ambos Sistemas de Identificación y Registro ya que no sólo se encuentran vigentes de manera paralela sino que se dilucidan sus efectos jurídicos tras las sustanciales diferencias en los abordajes y categorías de registro que plantean para reconocer y proteger el patrimonio cultural. Por lo tanto, este trabajo permite adentrarse al Registro General del Patrimonio Cultural venezolano desde el ámbito legal y desentrañar su aplicabilidad en aras de ser un tema poco explorado dentro del contexto nacional.
Assassin’s Creed: Origins y la idoneidad del videojuego de mundo abierto para la difusión del patrimonio
Authors: Morales Vallejo David
Published: February 2021

En el presente artículo se analiza la evolución de la imagen de entornos urbanos y patrimoniales recreados a modo de escenario en el ámbito del videojuego, desde las primeras y limitadas representaciones en etapas tempranas del medio, hasta el surgimiento de una realista escenografía tridimensional de concepto abierto, que da origen a un nuevo género de videojuegos donde el protagonismo recae, principalmente, en la relación que se establece entre el personaje manejado por el usuario y el mundo virtual en el que se desenvuelve libremente. Se genera así una aptitud de los denominados videojuegos de mundo abierto a la hora de recrear entornos monumentales de conocidas ciudades reales, que resulta especialmente interesante para la difusión del patrimonio, principalmente en el caso de la saga Assassin’s Creed, que hace de la recreación realista de ciudades históricas su seña de identidad. Es por ello que en esta investigación se da a conocer la trayectoria de la serie en el contexto de la difusión del patrimonio, se indaga sobre el tipo de asesoramiento histórico que reciben los equipos desarrolladores, y se aborda el paradigmático ejemplo de divulgación cultural que supone el episodio titulado Assassin’s Creed: Origins.
FERNÁNDEZ ADARVE, Gabriel Jesús. Granada, conjunto histórico: de la declaración a la intervención. Murcia, Universidad de Murcia, 2019.
Authors: Castillo Ruiz José
Published: February 2021

Este libro recoge los contenidos más relevantes de la tesis doctoral Conjuntos Históricos de Granada: Delimitación, planeamiento y rehabilitación (1985-2015) realizada por el arquitecto Gabriel Jesús Fernández Adarve y defendida públicamente con la máxima calificación en 2018.
HERNÁNDEZ MARTÍNEZ, Ascensión. Las ciudades históricas y la destrucción del legado urbanístico español. Fernando Chueca Goitia. Zaragoza, Prensas de la Universidad de Zaragoza, 2019.
Authors: Castillo Ruiz José
Published: February 2021

Uno de los intereses científicos y objeto de sus últimas investigaciones de la profesora de Historia del Arte de la Universidad de Zaragoza, Ascensión Hernández Martínez, es la restauración monumental y, en general, la protección del patrimonio históricoartístico en la amplia etapa del franquismo. Es en este contexto en el que se enmarca esta publicación de la Universidad de Zaragoza, en la que analiza un aspecto especialmente relevante y poco conocido hasta ahora de uno de los personajes cruciales (ya que supera con creces la simple condición de arquitecto restaurador o estudioso de la historia de la arquitectura) de este periodo como es Fernando Chueca Goitia, al que la autora ya le ha dedicado varios trabajos. Esta faceta a la que nos referimos es la de su actividad o más bien pensamiento en torno a la protección de las ciudades históricas que, como ahora veremos, él la aborda sobre todo desde la denuncia de su masiva y vergonzosa destrucción en las décadas de los sesenta y setenta del siglo XX, que es en el contexto histórico en el que Chueca escribe los textos objeto de análisis en esta publicación.
El patrimonio bibliográfico de España e Hispanoamérica: convergencias y divergencias
Authors: Castro Viguera Yenifer , Chávez Montejo Yarelys
Published: February 2021

Objetivos. La presente investigación tiene como objetivo el análisis de la concepción de patrimonio bibliográfico en el marco científico y legislativo, así como el estudio del régimen jurídico español de protección del mismo y el panorama hispanoamericano al respecto. Metodología. El proceso investigativo se ha basado en el examen de disposiciones normativas nacionales de España e Hispanoamérica, directrices de organismos internacionales, catálogos y sitios web de bibliotecas y otros centros de información, así como en la revisión bibliográfica especializada en el tema del patrimonio bibliográfico y/o histórico-cultural. Resultados. Tras el estudio realizado, se constata que aún subsisten deficiencias en muchos de los países concernidos, así como políticas heterogéneas en cuanto al tratamiento del acervo bibliográfico de carácter patrimonial. Conclusiones. Se subraya la necesidad de continuar avanzando en la integración regional, a través de normas y estrategias conjuntas de preservación y difusión del patrimonio bibliográfico, entre ellas los catálogos colectivos, bajo las directrices de organismos internacionales como la UNESCO, IFLA y ABINIA.
BEVAN, R. La destrucción de la memoria. La arquitectura en guerra. Valencia: La Caja. Gestión del Patrimonio, 2019.
Authors: Montiel Vera José Antonio
Published: February 2021

El libro aborda las apreciaciones culturales sobre el patrimonio arquitectónico de las diferentes sociedades que han vivido la destrucción y la reconstrucción de su memoria colectiva durante y después de las guerras mundiales e interétnicas que afectaron la vida cotidiana de las naciones y de los espacios locales.A grandes rasgos es una obra que nos permite acceder a la parte más subjetiva de la historia. A través del estudio de los efectos de la guerra en el patrimonio cultural arquitectónico de diferentes poblaciones del mundo, el autor reconstruye las experiencias humanas en situaciones de intervención bélica para explicar cómo se ha destruido la base simbólica de la memoria de un pueblo. Se interesa en reconstruir la historia del mundo, de sus guerras mundiales y sus guerras locales, ya que todas atentan contra la memoria, esta historia la lleva al campo de las imágenes en donde el patrimonio resiste o sucumbe ante los nuevos poderes. Con varios ejemplos que van desde la toma de Jerusalén en el siglo VI a la revolución francesa, de la destrucción de Versalles (1939) a la destrucción de Bagdad (2003), entre otros acontecimientos, el libro hace una dialéctica entre memoria y cultura material para explicar los significados que un grupo social otorga a las manifestaciones arquitectónicas.
El patrimonio Industrial Hidráulico en Sierra Nevada
Authors: Guerrero Ruiz Juan Carlos
Published: February 2021

Del diverso patrimonio industrial minero de la comarca del Zenete  ( Granada ), la historia de las centrales hidráulicas y sus maquinistas, contienen el conocimiento y la sabiduría tecnológica que se produjeron en los inicios de la industrialización, con la generación de la energía eléctrica y neumática a finales del siglo XIX.Este patrimonio, no tiene un valor histórico-artístico, no goza de un valor estético ni tampoco funcional en la actualidad, pero representa una parte de la cultura popular de la clase trabajadora, encierra la vida de los hombres y mujeres, campesinos explotados por la industria colonial minera, descubridores de una nueva economía moderna de asalariados que supone la transformación de su estructura social.Actualmente conforma un conjunto patrimonial histórico  sin protección en riesgo de desaparecer.
Flujo de trabajo para la digitalización 3d mediante fotogrametría automatizada de las tallas de madera policromada del Santísimo Cristo de la Sangre y su ángel.
Authors: Sanchez Allegue Paloma , Melendreras Ruiz Rafael , Marín Torres María Teresa
Published: February 2021

En el presente artículo se muestra el caso del Santísimo Cristo de la Sangre, talla escultórica del titular de una de las cofradías más antiguas de España cuya historia, valor artístico y degradación estructural progresiva demandaban una intervención urgente. También del ángel niño que recoge su sangre con un cáliz, permaneciendo aún desaparecidos tres de los cinco ángeles que originalmente le acompañaban. Este artículo pretende ser un ejemplo del potencial de la digitalización 3D para la restauración y recuperación del patrimonio, así como para su salvaguarda. Se trata del primer proceso de esta metodología desarrollado en tallas de la Semana Santa en la Región de Murcia (España), y además de la ejecución técnica detallada de dicho proceso, el artículo se centra también en la validación del flujo de trabajo desarrollado, la verificación técnica de la calidad de los resultados obtenidos y en las futuras aplicaciones de los modelos 3D resultantes para su propietaria, la Archicofradía de la Preciosísima Sangre de Murcia.
La Mezquita de Córdoba: un caso de destrucción simbólica del patrimonio.
Authors: Patrimonio de todxs Plataforma Mezquita-Catedral de Córdoba
Published: February 2021

La Mezquita de Córdoba fue incluida en 1984 en el listado del Patrimonio Mundial de la UNESCO. La organización internacional fijó cuatro criterios que justificaron su reconocimiento, todos ellos relacionados con su valor como ejemplo excepcional de la arquitectura islámica y andalusí en Occidente. Iniciado en el siglo VIII por Abd Al Rahman I, el universal monumento fue dedicado al culto católico en el siglo XIII y en el XVI incorporó una Catedral en su interior. En las dos últimas décadas de nuestra centuria, sus actuales administradores han puesto en marcha un modelo de gestión que persigue amputar sus señas de identidad originarias, en vulneración de los principios de autenticidad protegidos por la UNESCO. Este artículo examina lo que entiende como un caso de mutilación simbólica del patrimonio, en cierta manera análogo a la polémica conversión en mezquita de la basílica de Santa Sofía en Estambul impulsada por el presidente turco Recep Tayyip Erdogan.
PASTOR PÉREZ, A; PICAS, M. Y RUIZ MARTÍNEZ, A. (eds.) 21 Assajos al voltant del Patrimoni Cultural / 21 Ensayos sobre el Patrimonio Cultural. JAS Arqueología. Madrid, JAS Arqueología, 2020.
Authors: García Viana Diego
Published: February 2021

Rseña bibliográfica del libro 21 Assajos al voltant del Patrimoni Cultural / 21 Ensayos sobre el Patrimonio Cultural.