bluuebunny/crossref_metadata_2025 huggingface dataset:
Effective Project Management of a Pan-African Cancer Research Network: Men of African Descent and Carcinoma of the Prostate (MADCaP)
Authors: Odiaka Emeka , Lounsbury David W. , Jalloh Mohamed , Adusei Ben , Diallo Thierno Amadou , Kane Papa Moussa Sene , Rockson Isabella , Okyne Vicky , Irusen Hayley , Pentz Audrey , Makinde Ifeoluwa , Ajibola Olalekan Hafees , Petersen Lindsay , McBride Jo , Petersen Desiree C. , Mante Sunny , Agalliu Ilir , Adebiyi Akindele Olupelumi , Popoola Olufemi , Yeboah Edward , Mensah James E. , Hsing Ann , Fernandez Pedro , Aisuodionoe-Shadrach Oseremen , Joffe Maureen , Singh Elvira , Gueye Serigne Magueye , Quintana Yuri , Fortier Brian , Rebbeck Timothy R. , Andrews Caroline
Published: September 2018

Purpose

Health research in low- and middle-income countries can generate novel scientific knowledge and improve clinical care, fostering population health improvements to prevent premature death. Project management is a critical part of the success of this research, applying knowledge, skills, tools, and techniques to accomplish required goals. Here, we describe the development and implementation of tools to support a multifaceted study of prostate cancer in Africa, focusing on building strategic and operational capacity.

Methods

Applying a learning organizational framework, we developed and implemented a project management toolkit (PMT) that includes a management process flowchart, a cyclical center-specific schedule of activities, periodic reporting and communication, and center-specific monitoring and evaluation metrics.

Results

The PMT was successfully deployed during year one of the project with effective component implementation occurring through periodic cycles of dissemination and feedback to local center project managers. A specific evaluation was conducted 1 year after study initiation to obtain enrollment data, evaluate individual quality control management plans, and undertake risk log assessments and follow-up. Pilot data obtained identified areas in which centers required mentoring, strengthening, and capacity development. Strategies were implemented to improve project goals and operational capacity through local problem solving, conducting quality control checks and following compliancy with study aims. Moving forward, centers will perform quarterly evaluations and initiate strengthening measures as required.

Conclusion

The PMT has fostered the development of both strategic and operational capacity across project centers. Investment in project management resources is essential to ensuring high-quality, impactful health research in low- and middle-income countries.
Prepulse inhibition inDrosophila melanogasterlarvae
Authors: Matsumoto Yutaro , Shimizu Kazuya , Arahata Kota , Suzuki Miku , Shimizu Akira , Takei Koki , Yamauchi Junji , Hakeda-Suzuki Satoko , Suzuki Takashi , Morimoto Takako
Published: September 2018

The neural mechanisms of psychiatric diseases like autism spectrum disorder and schizophrenia have been intensively studied, and a number of candidate genes have been identified. However, the relationship between genes and neural system functioning remains unclear. Model organisms may serve as a powerful tool for addressing this question due to the availability of established genetic tools. Here, we report prepulse inhibition (PPI) in Drosophila larvae for the first time. PPI is a neurological phenomenon found in humans and other organisms and is used in the diagnosis of schizophrenia and other psychiatric disorders. A weaker prestimulus (prepulse) inhibits the reaction to a subsequent strong, startling stimulus (pulse). Using the larval startle response to the buzz of a predator (wasp), we examined PPI in wild-type flies and two mutants: an fmr1 mutant, which is implicated in Fragile X syndrome, and a centaurin gamma 1A (CenG1A) mutant, which is associated with GTPase, PH, ArfGAP, and ANK domains and implicated in autism. Both mutants showed decreased PPI, whereas, interestingly, double mutants showed substantial PPI. The PPI phenomenon described here can provide a useful tool for the study of neural mechanisms of synaptic modification and psychiatric diseases.
The class I myosin MYO1D binds to lipid and protects against colitis
Authors: McAlpine William , Wang Kuan-wen , Choi Jin Huk , San Miguel Miguel , McAlpine Sarah Grace , Russell Jamie , Ludwig Sara , Li Xiaohong , Tang Miao , Zhan Xiaoming , Choi Mihwa , Wang Tao , Bu Chun Hui , Murray Anne R. , Moresco Eva Marie Y. , Turer Emre E. , Beutler Bruce
Published: September 2018

Myosin ID (MYO1D) is a member of the class I myosin family. We screened 48,649 third generation (G3) germline mutant mice derived from N-ethyl-N-nitrosourea-mutagenized grandsires for intestinal homeostasis abnormalities after oral administration of dextran sodium sulfate (DSS). We found and validated mutations in Myo1d as a cause of increased susceptibility to DSS-induced colitis. MYO1D is produced in the intestinal epithelium, and the colitis phenotype is dependent on the nonhematopoietic compartment of the mouse. Moreover, MYO1D appears to couple cytoskeletal elements to lipid in an ATP-dependent manner. These findings demonstrate that MYO1D is needed to maintain epithelial integrity and protect against DSS-induced colitis.
Association between intensity of STI screening and development of antimicrobial resistance in N. gonorrhoeae in 12 cities in the USA: An ecological study
Authors: Kenyon Chris R.
Published: September 2018

In this study, we assessed if there was a city-level association between sexually transmitted infection (STI) screening intensity in men who have sex with men and antimicrobial sensitivity inNeisseria gonorrhoeaein the United States, 2007 to 2013.  We found positive associations between STI screening intensity and increases in minimum inhibitory concentrations for cefixime and azithromycin, but not ceftriaxone.
A descriptive study of potential participant preferences for the design of an incentivised weight loss programme for people with type 2 diabetes mellitus attending a public hospital in Lima, Peru
Authors: Akehurst Harold , Pesantes M. Amalia , Cornejo S. del Pilar , Manrique Katty , Lazo-Porras Maria , Portocarrero Jill , Diez-Canseco Francisco , Bernabe-Ortiz Antonio , Trujillo Antonio J. , Miranda J. Jaime
Published: September 2018

Background: Weight loss is important for the control of type 2 diabetes mellitus but is difficult to achieve and sustain. Programmes employing financial incentives have been successful in areas such as smoking cessation. However, the optimum design for an incentivised programme for weight loss is undetermined, and may depend on social, cultural and demographic factors.

Methods: An original questionnaire was designed whose items addressed respondent personal and health characteristics, and preferences for a hypothetical incentivised weight loss programme. One hundred people with type 2 diabetes mellitus were recruited to complete the questionnaire from the endocrinology clinic of a public hospital in Lima, Peru. A descriptive analysis of responses was performed.

Results: Ninety-five percent of subjects who had previously attempted to lose weight had found this either 'difficult' or 'very difficult'. Eighty-five percent of subjects would participate in an incentivised weight loss programme. Median suggested incentive for 1 kg weight loss every 2 weeks over 9 months was PEN 100 (~USD $30). Cash was preferred by 70% as payment method. Only 56% of subjects would participate in a deposit-contract scheme, and the median suggested deposit amount was PEN 20 (~USD $6). Eighty percent of subjects would share the incentive with a helper, and family members were the most common choice of helper.

Conclusions: The challenge of achieving and sustaining weight loss is confirmed in this setting. Direct cash payments of PEN 100 were generally preferred, with substantial scope for involving a co-participant with whom the incentive could be shared. Employing direct financial incentives in future weight loss programmes appears to be widely acceptable among people with type 2 diabetes mellitus.
Impact of multimorbidity on chronic oedema management in the older person
Authors: Todd Marie
Published: September 2018

The population is ageing but many older people are living with chronic multimorbidity, which has a significant impact of all aspects of quality of life. Many of the common chronic conditions suffered by older people either precipitate or compound chronic oedema, which means a wide range of skills and in-depth knowledge is required to deliver holistic care that does not interfere with other treatment modalities. This patient group often presents with highly complex coexisting issues that require highly specialist assessment and management in collaboration with other professionals.
Challenges of lymphoedema management in an ageing population
Authors: Pugh Stacy , Ives Angela , Stubbs Charlotte
Published: September 2018

The risk of developing chronic oedema increases with age. Many factors affect the successful management of this condition, which a robust holistic assessment will identify. This article discusses some of the challenges and complications associated with managing this long-term condition, alongside comorbidities and the effects of ageing. It will consider the implications of wider issues such as social care and the current healthcare economy. The challenges of lymphoedema management can be overcome by offering a collaborative approach to care. This can be achieved by specialist practitioners offering support, advice and guidance on how to ensure satisfactory outcomes for patients in a timely manner.
Make someone happy
Authors: Bissett Julie
Published: September 2018

Julie Bissett asks what better way to improve the interactions with your patients than with a smile
Things I wish I could tell my younger self
Authors: Bissett Julie
Published: September 2018

In any career, you collect some golden nuggets of knowledge to impart with those on the same path. Julie Bissett invited some Dental Nursing friends to share their own valuable insights
I ‘died’ for several minutes
Authors: Bradstock Kate
Published: September 2018

Dental nurse tutor Kate Bradstock shares a cautionary tale that fuelled her passion for an unusual pastime and reiterated the importance of ‘switch off’ time – as well as those critical first aid skills
Who picks up a dirty tissue?
Authors: Fowler John
Published: September 2018

John Fowler explores responsible relationships within your practice team
The ‘whole body’ approach
Authors: Lord Nina
Published: September 2018

Former dental nurse and dental therapist Nina Lord reveals her passion for complementary care
Calming a storm
Authors: Redman Lesley
Published: September 2018

Lesley Redman considers the importance of oral desensitisation in relation to dementia and additional needs

Aim

This article aims to describe the correct and effective use of desensitizing techniques

Objectives

Recognise techniques used in desensitising situations Explain how techniques used can be the difference in compliance and non compliance Discuss the best way to apply desensitising techniques. This article meets GDC development outcome A
Debunking dental myths
Authors: Pebble Melonie
Published: September 2018

Patients are full of interesting information gleaned from the internet. Here, dental therapist Melonie Prebble wades through the good, the bad and the alarming to offer some guidance on what to say when confronted with those questionable ‘facts’
Making legal and ethical issues a part of your ethos
Authors: Morris Rebecca
Published: September 2018

Identifying, resolving and prevention within a DCP's role
Systemic sclerosis: a case report and considerations for general dental practitioners
Authors: Wright Fiona , Besi Eleni , Malden Nicholas J
Published: September 2018

Abstract: Systemic sclerosis is a rare condition but has a high morbidity and mortality rate due to complications associated with the increased deposition of collagen in multi-organ systems. This can result in tightening of the skin, vascular issues and various autoimmune responses. This paper describes a case which was referred into secondary care, where confirmation of systemic sclerosis from the medical history aided the diagnosis of the oral symptoms and allowed appropriate patient management.

CPD/Clinical Relevance: General Dental Practitioners (GDPs) may encounter these patients in primary care and should be aware of the condition and its effects on the mouth.
The orthodontic/paediatric interface part 1
Authors: Carr Samantha , Barry Siobhan , Malik Ovais H
Published: September 2018

Abstract: This series discusses the interface between orthodontics and other dental specialties. The first part of this four-part series will discuss the orthodontic/paediatric interface. It will discuss some common problems encountered in paediatric dentistry where orthodontic input is necessary including: enforced extraction of poor-quality teeth, unerupted maxillary incisors, crossbites, trauma, impacted canines, space maintainers and ectopic eruption of first permanent molars. The second part will discuss the orthodontic/restorative interface; the third will focus on the orthodontic/periodontal interface and the final article will discuss the orthodontic/endodontic interface.

CPD/Clinical Relevance: Orthodontists and paediatric dentists work closely together to ensure that children have the appropriate treatment at the optimal time. General dental practitioners (GDPs) need to be able to identify and treat common problems and know when to refer to orthodontic or paediatric specialists.
Advance care planning and home death in patients with advanced cancer: a structured interview analysis
Authors: Ishikawa Takako , Fukui Sakiko , Okamoto Yuko
Published: September 2018

Background:

Discrepancy between preferred and actual place of death is common in patients with advanced cancer.

Aim:

To investigate the association between advance care planning (ACP) and home death in patients with advanced cancer.

Methods:

Using structured interviews, 44 primary nurses from 19 home-visit nursing agencies in Japan were asked about status changes for 123 advanced cancer patients receiving home care. The main outcome was the place of death.

Results:

Of the 123 patients, 16 were alive, 54 died at home and 53 died at hospital. Multivariate analyses revealed that home death was more likely if: i) physicians or nurses practised ACP during the whole home-visit period (odds ratio (OR) 41.76; confidence interval (CI) 5.87–297.07); ii) patients had adequate insight concerning their prognosis just before death or at hospitalisation (OR 7.85; CI 1.18–52.24); and iii) the baseline preference of families was a home death (OR 0.09; 95% CI 0.01–0.73).

Conclusion:

ACP practiced by physicians or nurses for advanced cancer patients may contribute to achieving home death.
Research roundup
Authors: Heggs Karen
Published: September 2018

Synopses of a selection of recently published research articles of relevance to palliative care
Be responsive in your teaching
Authors: Riches Adam
Published: September 2018

We should address the misconceptions that often crop up during classroom teaching as soon as they arise. But how is it possible to teach responsively? Adam Riches advises
Flúor na Água do Aquífero Bambuí no Oeste da Bahia (Brasil)
Authors: Gonçalves Manuel Vitor Portugal , Cruz Manoel Jerônimo Moreira , Santos Rodrigo Alves , Ramos Junior Antônio Bomfim da Silva , Coutinho Carlos Alberto Machado
Published: September 2018

Este artigo reporta uma investigação científica da hidrogeoquímica básica do Aquífero Bambuí no oeste da Bahia, com ênfase o flúor. Foram amostras de 61 poços durante os anos de 2011 (período chuvoso) e 2012 (período de estiagem). O pH variou entre 6,87 e 8,93, com predomínio de condições alcalinas. As fácies hidroquímicas bicarbonaradas cálcicas (56%), mistas cálcicas (20%) e as fácies bicarbonaradas sódicas (10%) foram as mais representativas no sítio de estudo, em que as concentrações do flúor excederam o limite ótimo local (0.8 mg.L-1) para 30% dos poços, que oscilaram de 0,1 a 6.2 mg.L-1 e média de 0.96 mg.L-1. A análise das Componentes Principais e a composição das amostras de água sugeriram a relevância do intemperismo químico para a mineralização e qualidade da água subterrânea; bem como para compreensão do enriquecimento em flúor. A origem do flúor reflete a importância do intemperismo das rochas que encaixantes do Aquífero Bambuí, e a dissolução de minerais hospedados nestas, para a qualidade da água. Recomenda-se, para o sítio de estudo, investimento público significativo na pesquisa em geociências, saúde pública e na dessalinização das águas salobras. Deve-se, também, priorizar o monitoramento da qualidade da água subterrânea, poluição por nitrato e a vigilância epidemiológica da fluorose dentária relacionada a ingestão dessas águas. Os resultados dessa pesquisa mostram a relevância da gestão dos recursos hídricos para melhora do saneamento básico e para a promoção da saúde pública.
Geoparque Seridó, RN: Avaliação dos seus geossítios com base nas categorias de valor intrínseco, científico, turístico e de uso/gestão
Authors: Gomes Cristiane Soares Cardoso Dantas , Nascimento Marcos Antonio Leite do , Medeiros Carlos Alberto Freire
Published: September 2018

O projeto Geoparque Seridó é resultado de um estudo técnico e diagnóstico que embasou a
inventariação de 25 geossítios, sendo reformulado e atualmente abrangendo 16 geossítios, contemplado
em seis municípios no estado do Rio Grande do Norte (Cerro Corá, Lagoa Nova, Currais Novos, Acari,
Carnaúba dos Dantas e Parelhas). Esses locais apresentam um patrimônio geológico único utilizado para
diferentes finalidades. Dessa forma, a pesquisa tem o intuito de evidenciar os valores que podem ser
encontrados nesses locais. Para confirmar tais valores, foi utilizada uma metodologia de quantificação do
patrimônio geológico. A pesquisa evidenciou dois geossítios (Mina Brejuí e Pico do Totoró) de relevância
internacional e oito geossítios de relevância nacional (Serra Verde, Vale Vulcânico, Cânions dos apertados,
Açude Gargalheiras, Cruzeiro de Acari, Xiquexique, Açude Boqueirão e Mirador), além de mostrar quais
geossítios têm finalidade científica, turística. Os resultados oriundos da pesquisa evidenciaram que a área
tem sim viabilidade para a efetivação da proposta do Geoparque e ratificam a importância do lugar ao ser
embasado nos valores apontados pela pesquisa.
Avaliação do bacharelado em Turismo no Brasil à luz do Exame Nacional de Desempenho dos Estudantes (ENADE)
Authors: Carvalho Alissandra Nazareth de , Holanda Luciana Araújo de , Martins Patricia Cristina S. , Novo Cristiane Barroncas Maciel Costa
Published: September 2018

O presente artigo tem como objetivo avaliar o curso de bacharelado em Turismo no Brasil com base nos indicadores dos cursos no Exame Nacional de Desempenho dos Estudantes (Enade), no período de 2006 a 2012, bem como conhecer a visão que as Instituições de Ensino Superior (IES) e as associações/entidades profissionais da área de turismo têm a respeito do referido exame. Para construção deste trabalho foram realizadas pesquisas bibliográfica, documental e de campo, nas quais foram aplicados questionários a docentes e coordenadores de cursos, bem como a representantes de associações e entidades de classe. Foi possível observar que o Enade é um instrumento de avaliação relevante que impacta na formação do estudante, bem como na atuação de coordenadores e professores de IES, ainda que a relevância desse processo e a infinidade de possibilidades de aprimoramento educacionais apresentadas pelo referido exame não estejam totalmente claras para esses acadêmicos e profissionais.
Avaliação da imagem de um destino turístico no Instagram
Authors: Zucco Fabrícia Durieux , Pereira Melise De Lima , Limberger Pablo Flôres , Falaster Christian Daniel
Published: September 2018

Com os avanços tecnológicos, as imagens postadas nas redes sociais de fotografia (Instagram) são utilizadas como ferramentas de avaliação pelos turistas, desta forma, o gerenciamento destas ferramentas são essenciais para os destinos turísticos. O objetivo desta pesquisa é avaliar a imagem do destino turístico Salvador, Bahia, Brasil, a partir das publicações de uma rede social de fotografia, o Instagram. O presente trabalho analisou 400 imagens marcadas no Instagram com a hashtag #salvador, sendo que para a categorização das imagens coletadas foram utilizadas as dimensões da imagem cognitiva e motivacionais de Baloglu e Mccleary (1999). A pesquisa é exploratória, com abordagem qualitativa e quantitativa. A coleta de dados foi realizada, de forma aleatória, na rede social Instagram, por meio do software Seekr Monitor, uma ferramenta para monitoramento e gestão das mídias sociais. Por meio de análise de regressão linear múltipla, identificou-se a existência de relações causais positivas e negativas entre as dimensões da imagem e motivacionais do destino turístico e o número de curtidas por seguidor no Instagram. Os resultados indicam que as Destination Management Organization (DMOs) de Salvador (BA) devem direcionar seus esforços promocionais nas redes sociais virtuais, envolvendo a formação da imagem de valor ao ambiente, em vez de comercializar o destino por meio dos apelos motivacionais do prestígio.
Architectural Contextualization of Heritage Museum Artifacts Using Augmented Reality
Authors: Nofal Eslam , Elhanafi Ahmed Magdy , Hameeuw Hendrik , Vande Moere Andrew
Published: September 2018

Context is crucial for understanding meanings and values of heritage. Several heritage artifacts from recently destroyed monuments are exhibited in different museums around the world. As such contextualizing those isolated heritage artifacts enables museums to communicate architectural and spatial qualities of the original context to their visitors. With the rapid evolution of digital technologies, museums started to incorporate Augmented Reality (AR) to present and interpret their collections in more appealing and exciting ways. AR allows both an enrichment of heritage communication, and also encouragement of interactivity in museums. Through a field study in a real-world museum environment, we investigated how AR enhances the communication of the original context of an isolated artifact from the Nimrud palace in Iraq. We deployed a mixed-method evaluation methodology that led to an effective and engaging communication of the architectural context of that artifact, particularly perceiving and recalling architectural features and spatial dimensions. We conclude the paper with a set of discussion points about how AR positively affects visitors’ memorability of architectural qualities, and how it provokes their curiosity to explore more information. We highlight some considerations about AR visualization, such as how levels of embellishment direct user’s focus of attention, and which aspects should be considered when using AR abstract visualization to communicate heritage. We outline several design recommendations to overcome current AR usability issues in museums about intuition, freedom of movement, and age-related differences.
The Sensitive Perception of Cultural Heritage’s Materiality through Digital Technologies
Authors: Serain Clément
Published: September 2018

This article focuses on the impact of digital technologies in the field of cultural heritage conservation and restoration (i.e., Conservation Science). It arises from thesis research I am currently preparing at Paris 8 University, in France. Having observed a renewal of our relationship to cultural heritage through information and communication technologies, I aim to explain how these technologies affect our sensitive perception and consequently our understanding of the materiality of virtually represented objects. In the double context of the museum institution and the conservation-restoration field, whose mission is not simply to transmit objects but also to transmit knowledge about the materiality of these objects, we will try to understand more precisely the effect of these digital technologies on sensory and temporal-spatial perception of objects important to cultural heritage.
Defining the Temperature Change of the Brake Disc
Authors: Menyhártné Baracskai M.
Published: September 2018

In the article the thermal analysis of the brake disc and separator disc of a high performance power machine will be presented. As example an agricultural vehicle with weight of 30000 kg and maximum travel speed of 40 km/h will be taken. At stopping the vehicle, the braking system located in the wheel body becomes activated. The traversing of the piston forces the brake discs to friction. Therefore significant amount of heat is generated, which needs to be derived from the system. The article presents the construction of the disc brake system. Providing boundary condition, the radial temperature change of the cooled part of the brake disc will be defined.
Achnanthales from historical Grunow collection in Porto Subzanski, Croatia
Authors: Riaux-Gobin Catherine , Ector Luc , Witkowski Andrzej , Igersheim Anton
Published: September 2018

In the historical Grunow collection in Vienna, a piece of a broken slide covered with mica contained diatom material from Porto Subzanski, a coastal environment in Croatia. This material was examined in scanning electron microscopy. Several poorly documented or improperly assigned taxa within the Achnanthales, namely in Amphicocconeis and Cocconeis, were re-examined. A new combination of Amphicocconeis and a new species of Cocconeis are proposed. The new species, Cocconeis subzanskiensis, is closely related to Cocconeis placentula, except for the lack of a characteristic hyaline sub-marginal rim on the raphe valve, and is compared with other marine taxa pertaining to the same group. Recently described in tropical environments, Cocconeis coronatoides has been found in the Grunow material.
The Helmets of Verucchio: Production and Significance
Authors: Negrini Claudio , Mazzoli Marta , Di Lorenzo Giorgia
Published: September 2018

Forty-eight helmets were discovered in the Villanovan necropoleis in Verucchio (Italy). Due to this large number of finds and the typological variety of the helmets, Verucchio can be considered a privileged observatory for the study of this class of materials. Helmets were in fact typical products of metallurgical workmanship. It is known that the Villanovan aristocracy in Verucchio based its self-portrayal extensively on the exaltation of its role and the warrior ideology. For this reason, rich panoplies were placed inside male burials, including in some cases helmets as well. This work, therefore, seeks to illustrate the main features of helmet production in Verucchio by examining the technical characteristics of the helmets in detail, identifying the craftsmanship and recognizing both original traits and those externally inspired.
New metrics for evaluating home plate umpire consistency and accuracy
Authors: Hunter David J.
Published: September 2018

The availability of pitch-tracking data has led to increased scrutiny of Major League Baseball umpires. While many studies have attempted to rate umpires based on their conformity to the rule book strike zone, players and managers tend to accept deviations from this zone, provided that umpires establish consistent zones within a game. Using tools from computational geometry, we propose new metrics for assessing the consistency and accuracy of an umpire’s ball and strike calls over the course of a game. We apply these metrics to pitch-tracking data on all ball and strike calls made during the 2017 MLB regular season, giving some characterizations of the variation in performance of MLB umpires. This analysis demonstrates that measures of consistency can complement current accuracy-based evaluations of umpires.
Crystal structure of (Z)-2-(2-(1,3-dioxo-1-(phenylamino)butan-2-ylidene)hydrazineyl) terephthalic acid-dimethylsulfoxide (1/1), C18H15N3O6 ⋅ C2H6OS
Authors: Mammadova Gunay Z. , Brito Iván , Cárdenas Alejandro
Published: September 2018

C18H15N3O6 ⋅ C2H6OS, P21/c (no. 14), a = 15.762(9) Å, v = 6.013(4) Å, c = 22.264(11) Å, β = 103.522(19)°, V = 2052(2) Å3, Z = 4, R
gt(F) = 0.0484, wR
ref(F
2) = 0.1348, T = 296(2) K.
Georg Picht
Authors: Hannig Nicolai
Published: September 2018

Vorspann

Mit seiner Artikelserie über die „deutsche Bildungskatastrophe“, die 1964 in der Wochenzeitung Christ und Welt erschien, traf der Altphilologe und Religionsphilosoph Georg Picht den Nerv der Zeit. Bis heute ist dieses Schlagwort im Gedächtnis geblieben, und bis heute gilt Picht als einer der bekanntesten Intellektuellen der „Bonner Republik“. Dennoch liegen Teile seiner Biografie noch immer im Dunkeln, wie Nicolai Hannig zeigen kann, der auf der Basis bisher kaum ausgewerteter Korrespondenz Pichts Umgang mit den Massenmedien und seine Netzwerke nachzeichnet. Es ergibt sich das überraschend zwiespältige Bild eines politischen Gelehrten, der virtuos auf der medialen Klaviatur zu spielen verstand, Reformen in Staat und Gesellschaft das Wort redete, aber von einem zutiefst elitären Kommunikationsverständnis durchdrungen war.
Non-covalent interactions observed in nevirapinium pentaiodide hydrate which include the rare I4–I−···O=C halogen bonding
Authors: Kryukova Mariya A. , Sapegin Alexander V. , Novikov Alexander S. , Krasavin Mikhail , Ivanov Daniil M.
Published: September 2018

In the course of screening for novel crystalline forms of antiviral drug nevirapine, co-crystallization of the latter with molecular iodine was attempted. This resulted in the formation of a hydrate salt form composed of the protonated nevirapinium cation and pentaiodide anion. In the X-ray structure of NVPH+I5
−·H2O, halogen and hydrogen bonding interactions were identified and studied by DFT calculations and topological analysis of the electron density distribution within the framework of QTAIM method at the B3LYP/DZP-DKH and M06/DZP-DKH levels of theory. Estimated energies of these contacts are 1.3–9.4 kcal/mol.
Two series of rare earth metal-rich ternary aluminium transition metallides – RE
6Co2Al (RE=Sc, Y, Nd, Sm, Gd–Tm, Lu) and RE
6Ni2.25Al0.75 (RE=Y, Gd–Tm, Lu)
Authors: Stegemann Frank , Janka Oliver
Published: September 2018

The rare earth metal-rich cobalt and nickel aluminium compounds with the general compositions RE
6Co2Al (RE=Sc, Y, Nd, Sm, Gd–Tm, Lu) and RE
6Ni2.25Al0.75 (RE=Y, Gd–Tm, Lu) have been synthesised from the elements by arc-melting, followed by annealing. Single-crystal X-ray diffraction experiments on Y6Co2.02(1)Al0.98(1) (Ho6Co2Ga type; Immm; a=944.1(2), b=952.4(2), c=999.0(2) pm; wR2=0.0452, 1123 F
2 values, 35 variables) and Y6Ni2.26(1)Al0.74(1) (Ho6Co2Ga type; Immm; a=938.30(5), b=959.45(5), c=996.05(6) pm; wR2=0.0499, 1131 F
2 values, 35 variables) revealed that the compounds form solid solutions according to the general formula RE
6(Co/Ni)2+

x
Al1−x
with different homogeneity ranges. The compounds of the Ni series can be obtained in X-ray pure form only with the nominal composition RE
6Ni2.25Al0.75. A significant increase of the U
22 component of the anisotropic displacement parameters of the Co/Ni2 atoms (4g site) was observed that requires a description of the structure with a split-position model at RT. Further investigations by low temperature (90 K) single-crystal X-ray diffraction experiments of Y6Co2.02(1)Al0.98(1) showed a significant decrease of U
22. Magnetic measurements were conducted on the X-ray pure members of the RE
6Co2Al (RE=Y, Dy–Tm, Lu) series. Antiferromagnetic ordering was observed for the members with unpaired f electrons with Néel temperatures up to T
N=48.0(1) K and two spin reorientations for Dy6Co2Al.
Introduction of New Tensile Specimen Geometry for Property Evaluation in Stamped Parts
Authors: Justice Grant G. , Sergueeva Alla V. , Frerichs Andrew E. , Meacham Brian E. , Cheng Sheng , Branagan Daniel J.
Published: September 2018

Reliable tensile data are crucial in the automotive design process, particularly for the implementation of new Advanced High Strength Steel grades that can be used in new intricate shapes. The property evaluation of specific subsections of a complex part, such as a metal stamping, requires deviation from standard-sized specimens because of material quantity limitations which force the use of smaller specimens. A new tensile geometry is introduced for testing regions within parts that were previously difficult to characterize. However, the specimen size effect is not consistent between different steels, as demonstrated for this new geometry herein. Tensile property measurements taken with noncontact extensometers from specimens of three different sizes from three different sheet steels showed varying material responses to changes in specimen geometry.
O desenvolvemento político pre-municipal dos pobos galaicos
Authors: Fernández Calo Martín
Published: September 2018

Examínanse o entramado socio-político e as institucións recoñecíbeis no período «pre-municipal» da Callaecia, acotado ante quem pola latinización xurídica de Vespasiano. Isto permite identificar e contextualizar un proceso de afianzamento constitucional nas comunidades galaicas previo á súa municipalización alto-romana.
Prospección arqueológica en San Vicente de Meá (Mugardos). Un territorio costero entre la Antigüedad y la Edad Media
Authors: Carlsson-Brandt Fontan Erik , Fernández Abella David , Brookes Stuart , Sánchez Pardo José Carlos , Varela Gómez David
Published: September 2018

Se presentan y analizan los resultados de la campaña de prospección arqueológica geofísica (mediante magnetómetro) y visual de superficie en las inmediaciones de la iglesia de San Vicente de Meá (Mugardos, A Coruña). Se trata de una zona de gran interés arqueológico para entender la transición entre el mundo romano y el medieval. En este trabajo se complementarán los resultados de la prospección arqueológica con una revisión exhaustiva de otras fuentes de información histórica sobre esta zona (documentación, folklore y toponimia) para finalmente ofrecer una propuesta de interpretación histórica de la evolución entre la Antigüedad y la Plena Edad Media de este microespacio litoral gallego.
La alfarería tradicional de Buño. Una aproximación desde la arqueología y la arqueometría
Authors: Lantes-Suárez Oscar , Doval Galán José Francisco , Prieto Martínez María Pilar
Published: September 2018

En este trabajo presentamos los resultados de los análisis químicos realizados a cerámica y barros de Buño recogidos de diversos informes, memorias y trabajos académicos, inéditos a día de hoy. A través del estudio de la mineralogía y la composición elemental de un conjunto de cerámicas y de barros de Buño y de otros centros productores del NO peninsular introducidos como contraste, hemos podido constatar la buena calidad de las pastas de Buño que destacan por ser básicamente caolinítico-cuarcíticas. El tratamiento de los barros, extraídos de barreiros locales que proceden de la alteración hidrotermal de esquistos se mantiene constante a lo largo del tiempo sólo modificándose parcialmente en la actualidad, en especial en los materiales constructivos. Complementariamente hemos recopilado información relativa a las fuentes arqueológicas disponibles en la actualidad, avanzamos una actualización de la clasificación tipológica y finalmente hemos propuesto varias líneas de investigación futuras en el afán de enfocar los nuevos estudios arqueométricos dentro de una perspectiva arqueológica. Este estudio supone una puesta al día en las investigaciones relacionadas con la alfarería popular de Buño.
Hallazgo de un triente emeritense de la serie LATINA MVNITA en Cáceres (España)
Authors: González García Alberto , Martínez Chico David
Published: September 2018

El artículo documenta el hallazgo de un triente suevo con leyenda  LATINA EMERI MVNITA en el norte de la provincia de Cáceres (España). Su localización refuerza el tradicional origen atribuido a esta tipología, en la ceca de Emerita y no en territorio gallego.. Se discute la naturaleza y cronología de estas piezas.
Igrexiña fronte ao mar. Unha salgadura romana en Nerga (Cangas, Pontevedra)
Authors: Gorgoso López Lino , Acuña Piñeiro Angel
Published: September 2018

No presente artigo damos conta dunha pouco coñecida escavación de urxencia executada no ano 1996 en A Igrexiña, Nerga (Cangas, Pontevedra). A localización dunha serie de interesantes estruturas romanas relacionadas con estanques de salgadura e unha zona de posible uso doméstico, os materiais e o importante conxunto de restos óseos e de malacofauna, lévanos a unha reflexión sobre este tipo de xacementos no NW, tan en boga nos últimos anos.
Factores asociados al acceso a la atención prenatal en los hospitales de Huaral y Chancay, Perú
Authors: Rivera Felix Lauro Marcoantonio , Burgos López Nancy Haydee , Gomez Diaz Jossy Zulema , Moquillaza Alcántara Victor Hugo
Published: September 2018

Introducción. La atención prenatal aún no cubre al total de gestantes, situación que se repite en Latinoamérica y son pocos los estudios que evalúan las barreras que explican este fenómeno. El objetivo del presente estudio fue determinar los factores asociados al acceso de la atención prenatal en sus dimensiones de atención oportuna y cobertura. Métodos. Estudio de enfoque cuantitativo, observacional y analítico, realizado en 110 puérperas de los hospitales de Huaral y Chancay, Perú. Se evaluaron los factores (personales y sociodemográficos) asociados al acceso a la atención prenatal de acuerdo a su cobertura (mínimo 6 controles) y atención oportuna (primer control <14 semanas). Se realizó un análisis de regresión logística multivariada considerando un nivel de confianza del 95%. Resultados. Se halló que el olvido de las citas se muestra como un factor asociado a la cobertura inadecuada de la atención prenatal (p=0,048), mientras que la presencia de un seguro de salud, previo al control prenatal, se asoció a la atención prenatal oportuna (p=0,013). Conclusiones. La ausencia de olvido de las citas y la presencia de un seguro de salud previo al embarazo se asocian con el acceso a la atención prenatal.
Microlitiasis alveolar pulmonar: presentación de un caso
Authors: Somocurcio V. Jose G. , Sotomayor E. Alfredo , Luna A. Teresa , Cahuana Aparco Judith , Calongos Porras Estefanny , Bermejo Cataño Pedro , Tejada Llacsa Paul
Published: September 2018

La microlitiasis alveolar pulmonar es una enfermedad rara cuya principal característica es la acumulación de sales de calcio dentro del alvéolo pulmonar, esto debido a la presencia de una mutación genética autosómica recesiva. Esta entidad se encuentra dentro del grupo de enfermedades pulmonares difusas y el diagnóstico principal es un reto para los profesionales de la salud. No existe un tratamiento hasta la fecha; se ha planteado el uso de bisfosfonatos, los esteroides y lavado bronco alveolar sin llegar a resultados concluyentes. Se prefiere llevar a cabo el trasplante pulmonar, para mejores resultados, antes de que se haya establecido el desarrollo de la insuficiencia ventricular derecha. El diagnóstico definitivo es histopatológico. De acuerdo con la literatura nacional publicada, a nuestro alcance, en Perú se ha reportado esta enfermedad tan solo con sospecha radiológica, sin publicar el diagnóstico histopatológico definitivo. Presentamos un caso diagnosticado en el Departamento de Cirugía de Tórax y Cardiovascular del Hospital Nacional Hipólito Unanue de Lima.
Gutiérrez-Noriega y el debate en torno al consumo de las hojas de coca (1937-1952)
Authors: Ayala Pío Salomón , Murillo Peña Juan Pablo
Published: September 2018

El presente estudio es una investigación histórica académica que analiza la obra del investigador Sanmarquino Carlos Gutiérrez-Noriega en el debate sobre las implicancias sanitarias del consumo de la hoja de coca en la población peruana. Se analiza el contexto de las discusiones en la época central del estudio y se sistematiza los diversos estudios realizados por Gutiérrez-Noriega y sus colaboradores acerca del hombre andino y el consumo de hojas de coca en el Perú y los efectos de la cocaína a nivel de observaciones experimentales. Se examina la influencia de la evidencia generada por el autor sobre los efectos perjudiciales de la coca en los debates y decisiones de política en torno al consumo de la hoja de coca a nivel nacional e internacional.
Estabilidad de constituyentes bioquímicos conservados en dos tipos de tubos primarios: estudio mediante el criterio combinado de variabilidad analítica y biológica
Authors: Saldaña Orejón Italo Moisés , Benites Ricra Miguel Angel , Ortiz Canasa Francisco Javier
Published: September 2018

Sr. Editor. La demora en la medición de una magnitud bioquímica puede originar errores en la interpretación de los resultados debido a la variación de los componentes de la muestra, por tal razón queremos compartir un estudio cuyo objetivo fue determinar la estabilidad de 27 constituyentes bioquímicos conservados a temperatura de refrigeración en dos tipos de tubos primarios, valorados mediante el criterio combinado de variabilidad analítica y biológica.
Efecto antibacteriano de Psidium guajava L y Psidium acutangulum Mart sobre Streptococcus mutans
Authors: Afonso Josmary , García Aurimar , Golindano Johanna , Sleiman Julia , Fernandes Andreína
Published: September 2018

Objetivo: Evaluar el efecto antibacteriano in vitro de los extractos de Psidium guajava L (P. guajava) y Psidium acutangulum Mart. ex DC (P. acutangulum) sobre cepas aisladas de Streptococcus mutans (S. mutans) y la cepa control ATCC 25175. Métodos: Los extractos se obtuvieron de frutos sanos y frescos de guayaba en su estado verde y maduro de las especies mencionadas. La identificación de S. mutans a partir de muestras de pacientes con caries cavitadas (código 5 según ICDAS) y de la cepa control se realizó mediante la siembra en agar Mitis Salivarius, en condiciones de anaerobiosis, a 37 ºC, durante 48 horas, observándose colonias azules, rugosas, y las pruebas de susceptibilidad se realizaron mediante el método de difusión en disco con los extractos obtenidos. Resultados: S. mutans fue sensible al extracto de las cáscaras de P. guajava en estadio verde, tanto para la cepa control, como para la cepa del paciente, observándose el mayor halo para S. mutans ATCC 25175, reportándose un porcentaje de inhibición de 43,8%. Conclusiones: Los extractos de las cáscaras de P. acutangulum y P. guajava tienen efecto antibacteriano sobre S. mutans, representando una opción alternativa frente a este microorganismo, siendo un posible producto complementario a la prevención del desarrollo de la caries dental.
Actividad antibacteriana in vitro de Croton lechleri sobre Streptococcus mutans
Authors: Avilés Hidalgo Iván André , Dona Vidale Marina Antonia , Cabezas Abad Christian Andrés , Quisiguiña Salem Cinthya María
Published: September 2018

Objetivo: El propósito del presente estudio fue determinar la actividad antibacteriana de Croton lechleri (C. lechleri) sobre cepas de S. mutans ATCC 35668. Métodos: Se utilizó concentraciones al 50, 75 y 100% de C. lechleri, como control positivo a la clorhexidina 0,12% y al agua destilada como control negativo. Se midieron los halos de inhibición producidos alrededor de discos embebidos con cada una de las concentraciones de C. lechleri sobre colonias de S. mutans sembradas en Agar Muller Hinton. Resultados: Las concentraciones al 75% y 100% de C. lechleri mostraron actividad antibacteriana in vitro sobre S. mutans, la concentración al 50% no manifestó ninguna actividad. La clorhexidina al 0,12% mostró mayor actividad antibacteriana in vitro que las concentraciones de C. lechleri en los grupos de estudio evaluados. Conclusiones: Croton lechleri puede ser una alternativa natural, accesible y de bajo costo para métodos de prevención en caries dental al utilizarse al 75 y 100%.
La importancia de las ciencias básicas en la formación del cirujano dentista
Authors: Quispe-Salcedo Angela
Published: September 2018

Explicar la ciencia no es tarea sencilla. Desde una aproximación actual, la ciencia puede definirse como una descripción sistemática de un determinado fenómeno presente en la naturaleza 1; donde la observación y la interpretación se interrelacionan para dar lugar a un nuevo conocimiento que se estandariza mediante el uso del método científico. Dentro de este contexto, la ciencia puede ser dividida en básica y aplicada, teniendo cada una características y objetivos distintos.
Tratamiento odontológico de un paciente con la enfermedad de Riga-Fede. Reporte de caso clínico
Authors: Munayco Pantoja Evelyn Del Rosario , Torres Ramos Gilmer , Huapaya Paricoto Olinda , Chein Villacampa Sylvia Antonieta
Published: September 2018

La enfermedad de Riga-Fede es un trastorno benigno poco común, se caracteriza por una ulceración reactiva de la mucosa oral, que surge de lesiones traumáticas repetitivas. El trauma constante puede provocar una ulceración lo suficientemente grande como para interferir en la adecuada succión y alimentación, lo que provocaría un riesgo de deficiencias nutricionales, deshidratación e infecciones. Tenemos como ayuda diagnostica, la radiografía intraoral, que en lactantes es tomada con la técnica de Mannkopf. Con respecto al tratamiento de esta lesión hay variada información en la literatura y ha cambiado a lo largo de los años, existen tratamientos conservadores como radicales. Se presenta el caso clínico de un bebe de sexo masculino de 7 meses, el cual presenta una ulcera en la cara ventral de lengua, con bordes definidos, de aproximadamente 3,5 cm x 2,5 cm de diámetro, de color rojizo con áreas blanquecinas, dolorosa a la palpación, cursa con fiebre y con problemas de alimentación. Ingresa por infectología al Instituto Nacional de Salud del Niño, donde se le realizan múltiples exámenes auxiliares, sin poder hallar el diagnóstico, es referido al Servicio de Cirugía Buco Maxilofacial, donde es diagnosticado y tratado con éxito.
Ameloblastoma sólido plexiforme multiquístico en cuerpo mandibular izquierdo. Reporte de caso
Authors: González Rebattú Mauricio , Nieto Munguía Ana María , Muñoz Torres Carlos , Sánchez Sánchez Adalberto
Published: September 2018

En el 2017 la Organización Mundial de la Salud describió al ameloblastoma como una neoplasia benigna, localmente invasiva, consistente en una proliferación de epitelio odontogénico, que usualmente presenta un patrón folicular o plexiforme, y se encuentra dentro de un estroma fibroso. Cursa con un lento crecimiento y gran afinidad por el tejido óseo, presenta un alto índice de recurrencia, aproximadamente de 60 a 80%, si no es removido de la manera adecuada. Algunas variantes como la uniquística y la desmoplásica cuentan con un mejor pronóstico que la sólida o multiquística. Representan el 1% de todos los tumores de la mandíbula y el 11 % de todos los tumores odontogénicos. Se presenta el caso clínico de un paciente masculino de 43 años de edad que acude a nuestro servicio en el 2016 por presentar aumento de volumen con un año de evolución, asintomático, y con principios de movilidad dental en la zona mandibular izquierda. A la exploración intraoral se aprecia aumento de volumen en región mandibular con un incremento de expansión de las corticales, lo cual es involucrado desde la pieza dentaria 36 a la 41, no presenta sintomatología dolorosa a la palpación ni a la percusión.
Modelo Computacional Aplicado al Comportamiento de Agentes Financieros Mediante Autómatas Celulares (Cell-DEVS)
Authors: Barrantes Limahuaya Jesús , Pino Romero Neisser , Wainer Gabriel
Published: September 2018

En el presente trabajo se realizará la simulación el efecto de la interdependencia y el contagio en las decisiones de compra y venta de los inversionistasen un mercado financiero de tipo Black-Schole,donde existen dos activos financieros: acciones (activo riesgoso) y bonos (activo libre de riesgo); y dos estados del inversionista: amante y averso al riesgo; bajo distintas probabilidades de contagio. Este fenómeno económico-financiero podría ser modelado por un sistema de ecuaciones estocásticas; sin embargo, no todas las ecuaciones estocásticas tienen una solución cerrada por lo que se opta por realizar simulaciones computacionales para analizar su comportamiento numérico, en este sentido, se realizará una simulación computacional mediante los autómatas celulares.