bluuebunny/crossref_metadata_2025 huggingface dataset:
The involvement of AtMKK1 and AtMKK3 in plant-deleterious microbial volatile compounds-induced innate immunity.
Authors: Chang Ching-Han , Wang Wu-Guei , Su Pei-Yu , Chen Yu-Shuo , Nguyen Tri-Phuong , Xu Jian , Ohme-Takagi Masaru , Mimura Tetsuro , Huang Hao-Jen
Published: January 2024

​​ Microbial volatile organic compounds (mVCs) are a part of a
collection of microbial secondary metabolites with biological effects on
all living organisms. mVCs could function as gaseous modulators of plant
growth and plant health. In this study, the defense events induced by
plant-deleterious mVCs were investigated. E. aerogenes VCs
lead to growth inhibition and plant defense responses such as callose
deposition, and ROS accumulation in Arabidopsis thaliana. Data
from transcriptional analysis suggests that genes involved in the
hypoxia response pathway were enriched in the short exposure
up-regulated genes, E. aerogenes VCs induced high
transactivation of defense, immune, and metabolic processes after long
exposure. In addition, the transcript abundance of the genes involved in
the synthetic pathways of antimicrobial metabolites camalexin and
coumarin was enhanced after the E. aerogenes VCs exposure.
MKK1 and MKK3 were identified as the regulators of the camalexin
biosynthesis expression and E. aerogenes VCs-induced
callose deposition. The transactivation activity of the coumarin
biosynthesis pathway was only regulated by MKK3. Collectively, these
studies provide molecular insights into immune responses by
plant-deleterious mVCs.
Conduction System Pacing in a Patient with Persistent Left Superior Vena Cava and Absent Right Superior Vena Cava.
Authors: Zaraket Fatima , casteigt benjamin , Jimenez Jesus , González Carlos , Valles Ermengol
Published: January 2024

An 83 year-old man underwent attempted cardiac resynchronization therapy
(CRT-P), but was found to have a persistent left superior vena cava
(SVC) and absence of a right SVC. Additionally, no suitable coronary
sinus (CS) veins were found. Instead, conduction system pacing with a
modified approach was used.
Mollusk allergy in shrimp-allergic patients: still a complex diagnosis. An Italian multicenter study
Authors: Scala Enrico , A Aruanno , Elisa Boni , Brusca Ignazio , Francesca Cappiello , Elisabetta Caprini , Buzzulini Francesca , Deleonardi Gaia , A Demonte , Farioli Laura , Lodi-Rizzini Fabio , Losappio Laura , Macchia Donatella , Manzotti Giuseppina , Giorgia Meneguzzi , Marcello Montagni , Nucera Eleonora , Rosa Onida , Pastorello Elide Anna , peveri silvia , Radice Anna , Rivolta Federica , Rizzi Angela , Giani Mauro , Cecchi Lorenzo , E Pinter , Marzia Miglionico , L Vantaggio , V Pravettoni , Villalta Danilo , Asero Riccardo
Published: January 2024

Introduction |Shellfish allergy is an important cause
of food allergies worldwide. Both in vivo and in vitro
diagnostics failure nowadays is caused by the poor quality of the
extracts associated with the scarce availability of allergenic molecules
in the market. It is known that not all patients with shellfish
allergies experience adverse reactions to mollusks. It is still unclear
how to detect and diagnose correctly these patients. Aim
|To investigate the features of shrimp-allergic patients
either reactive or tolerant to mollusks, with the currently available
diagnostic methods. Methods| Nineteen centers,
scattered throughout Italy, participated in the study, enrolling
patients allergic to shrimp with or without associated reactions to
mollusks. Patients underwent skin tests using commercial extracts or
fresh raw and cooked foods, and IgE reactivity to currently available
allergenic extracts and molecules was measured in vitro.
Results| Two hundred and forty-seven individuals with
a history of adverse reaction to crustaceans participated in the study.
Only 47.8% of them reacted after cephalopod or bivalve ingestion. None
of the tests used, either in vivo or in vitro, was able to
detect all selected patients. Accordingly, a great heterogeneity of
results was observed with an agreement between in vivo and
in vitro tests ranging between 52% and 62% of cases. Skin tests
were able to identify the cephalopod and bivalve reactors (p
<0.001), also using fresh cooked or raw food (p
<0.001). The reactivity profile of mollusk reactors was
dominated by Pen m 1, over Pen m 2 and Pen m 4 compared to the tolerant
subjects, but 33% of patients allergic to shellfish were not detected
by any of the available molecules. A higher frequency of shrimp
hypersensitivity was recorded in northern Italy, while mollusk
reactivity was more frequent in the center-south. Conclusion
|The current diagnostic methods are inadequate to predict the
cross-reactivity between crustaceans and mollusks. The detection of
mollusks hypersensitivity must still rely on skin tests with fresh
material. There is no need to exclude mollusks from shrimp allergic
patients’ diet unless clinical history, the available diagnostic
instruments, and/or tolerance tests support such a decision. Primary
sensitization to mollusks seems possible.
The strength of hERG inhibition by Erythromycin at different temperature might be due to its different critical binding sites on the channels
Authors: chen yuan , Zhang Qian , Cheng Dongrong , Zhang Yanting , Xu Jianwei , Zhong Dian , Wei Xiaofeng , wang Jingtao , Liu Huan , Yu Junjie , Yang Jiaxin , Pan Lanying , Zhao Wei
Published: January 2024

The human ether-a-go-go-related gene (hERG) inhibition is a serious
cardiac safety issue. Although the inhibition of hERG by majority of
compounds are stable, the strength of the inhibition of a few compounds,
including Erythromycin, is remarkably rising from room temperature (RT)
to physiological temperature (PT). Understanding the features of
erythromycin against hERG could help us to decide which compounds are
needed for further study. The whole cell patch clamp technique was used
to investigate the effects of erythromycin on hERG channels in different
temperatures. We found that erythromycin caused a concentration
dependent inhibition of cardiac hERG potassium channels. The half
maximal inhibitory concentration (IC50) value was 1671 ± 593 μM (n =
5-10) at RT, about 11 folds higher than its IC50 (150 ± 26 μM, n = 7) at
PT. Although temperature does have a profound change of hERG channel
dynamic, the erythromycin further left shifted channel’s steady state
activation, steady state inactivation, and make onset of inactivation
significantly faster at both temperatures. It is interesting that our
data suggests that there is critical binding site shifted from V625 at
RT to Y652 at PT. By contrast, Cisapride, a well-known hERG blocker and
its inhibition is not affected by temperature, does not change its
critical binding sites after the temperature is raised to PT. The data
suggests that increase strength of the inhibition could be duo to the
shift of its binding sites of hERG channels.
Anabolizantes vs. reproducción en equinos
Authors: Moreno Carrillo Paula Juliana , Molina Ramos Carmen Leonide , Colmenares López Johana Andrea , Martínez Molina Angélica Andrea , Torres Murcia Kelly Alejandra
Published: January 2024

El uso de agentes anabólicos en equinos tiene como objetivo mejorar la ganancia de peso, los niveles de energía y la masa muscular especialmente en caballos que se están recuperando de alguna enfermedad, cirugía, sobreesfuerzo, entre otros. Deben tenerse en cuenta los efectos adversos en la reproducción equina como consecuencia del manejo inadecuado de estos fármacos. En yeguas puede generar disfunción ovárica, alteraciones en el ciclo estral y desarrollo de características masculinas. Por otra parte, en los sementales tiene como resultado la disminución de la masa testicular, la alteración en la producción espermática y cambios comportamentales, que pueden ser reversibles o irreversibles teniendo en cuenta la edad, el sexo, la vía, la dosis y la frecuencia de administración del anabolizante. Este trabajo recopila información sobre los efectos de los anabolizantes en la reproducción equina, con el propósito de generar conciencia en el uso de estas sustancias y crear políticas de prevención en la aplicación indiscriminada de estos fármacos.
Mejoramiento en un sistema de producción bovino semi-confinado en la empresa La Cosmopolitana Agroecológica Ltda del municipio de Restrepo – Meta
Authors: Rodríguez Barrera Fredy Fabián , Jaramillo-Hernández Dumar Alexander , Donato Julio Cesar
Published: January 2024

La creciente demanda de alimentos derivados de los animales, en las economías que más rápido crecen en el mundo ha incrementado significativamente la producción ganadera, con la ayuda de importantes innovaciones tecnológicas y cambios estructurales en el sector. El Sistema semi-intensivo en la producción bovina es una de las técnicas disponibles de intensificación del engorde de bovinos a pasto, donde el objetivo del Semiconfinamiento es aumentar los resultados zootécnicos como ganancia de peso diario, producción de carne por hectárea, rendimiento y el nivel de acabado de la carcasa. Un punto importante en este manejo es el suministro correcto de la ración concentrada, este debe realizarse diariamente en las cantidades correctas por lote de animales, siempre en los mismos horarios, además la implementación de subproductos de producciones agropecuarias ayudan a mejorar aspectos de una buena nutrición, disminuir la contaminación ambiental y mejorar el factor económico para nuestros campesinos. A continuación se describe el mejoramiento de un sistema de producción bovina gracias al asesoramiento de la empresa la Cosmopolitana Agroecológica Ltda del municipio Restrepo, Meta, donde se identificó que la producción obtuvo buenos resultados de acuerdo a la dieta usada, implementando también subproductos y así generando una mejor rentabilidad.
Guidelines for “Blue-Green” Urban Infrastructure: Adaptive Model and its Structural Elements
Authors: Ruban Liudmyla
Published: January 2024

An author's methodological approach has been developed, based on the planning of a “blue-green” urban infrastructure for the conditions of a riverside city, as one of the possible ways to adapt settlements to climate change. An adaptive model of the “Blue-green” infrastructure of a riparian city is proposed, as well as a typology of its structural elements, purposes, and methods of application. This methodological approach develops certain provisions of the Sponge Cities practical urban planning strategy, applicable for versatile climatic conditions and successfully implemented since the 2000s in several Asian countries (Singapore, China, etc) and many European cities.
Current status of secondary social studies teachers’ lessons related to social minorities
Authors:   Research Institute of Science Education, Lee Jungwoo
Published: January 2024

This study aims to understand the current experiences of secondary school social studies teachers in teaching lessons related to social minorities, and to explore ways to improve the way social minorities are addressed in the curriculum, textbooks, and lessons. To achieve these goals, I conducted a survey and interviews. 66 secondary school social studies teachers nationwide participated in the survey and 5 in the interviews. Based on the results of the survey and interviews, the current secondary school social studies teachers are teaching “dry” classes that rely on textbooks and avoid controversy as much as possible due to their caution towards students who belong to social minorities and students who have negative attitudes towards social minorities. The implications of the findings are discussed in terms of the social studies curriculum and textbooks as follows. First, in terms of the social studies curriculum, it is suggested that more detailed guidelines for teaching about social minorities should be provided. Secondly, I suggest that the way in which social studies textbooks address ‘values issues’ needs to be reviewed and revised.
Investigation of the gamma shielding efficiency reduction by depositing PbO and MnO2 composition on various types of substrates
Authors: Alhamdi Walat , Khalil Mohammed
Published: January 2024

In this study, a PbO, MnO2, PbO + MnO2 thin film (nano layer) was deposited
onto a microscope glass, indium tin oxide glass, and aluminum with
thicknesses 0.1 mm and 0.5 mm substrate, samples were prepared by the
thermal spray technique. The coating of thin films was carried out onto the
substrate at a temperature of 35?C, furthermore, the prepared shield films
were annealed at 100?C and 250?C for one hour. The shielding efficiency of
each thin film on each substrate at different temperatures was analyzed
using radioactive source 60Co and NaI(Tl) well-type scintillation detector.
The experimental results obtained were summarized: adding PbO or MnO2
thin film together or separately to the substrate increases the attenuation of gamma-rays depending on the type of samples and annealed
temperature. The minimum gamma reduction rate was found 0.3 % for indium tin
oxide glass deposited with MnO2 and annealed at 250?C while the maximum
was found in Al with thickness 0.1 mm (9.6 %) deposited with both PbO or MnO
2 together. This means that shielding efficiency increases by increasing
the thickness of the thin film, annealed temperature and substrate type.
Comparison of the effects of MoSi2 and CrSi2 on sintering and properties of titanium diboride (TiB2)
Authors: Gubernat Agnieszka , Zych Łukasz , Zientara Dariusz , Kornaus Kamil , Komarek Sebastian , Skorupa Natalia , Pędzich Zbigniew
Published: January 2024

Titanium diboride (TiB2) is a typical material classified as structural
ceramics. However, sintering of TiB2 ceramics is difficult mainly because of
a significant fraction of covalent bonds in the structure. In order to
obtain dense TiB2 ceramics various additives are used to improve its
sinterability. In this study, we investigated effects of MoSi2 and CrSi2
additions on sintering and properties of TiB2 prepared by hot-pressing
technique. The sintered materials were characterized in terms of apparent
density and microstructure. Their mechanical properties (bending strength,
Vickers hardness and fracture toughness) and oxidation resistance were
determined. It was found that the obtained composites are characterized by
high density and microstructure characteristic for cermets (TiB2-MoSi2). The
activators used for sintering did not deteriorate mechanical properties of
TiB2 sintered bodies. The oxidation resistance of the polycrystals with
chromium silicide addition reaches 1400?C. Based on the carried-out
studies, CrSi2 was found to be a promising sintering additive.
Improving the steel corrosion resistance of calcium hexaaluminate with addition of M2O5 (M = Nb, Ta)
Authors: Wen Tianpeng , Wang Zhipeng , Jin Yao , Yu Jingkun , Yan Zhengguo , Liu Zhaoyang , Yuan Lei
Published: January 2024

Calcium hexaaluminate (CA6) materials have garnered attention for their
potential use as lining materials in metallurgical furnaces during the
steel-making process. The present work explored the effects of M2O5 (M = Nb,
Ta) on the steel corrosion behaviour of calcium hexaaluminate combined with
the evolution of physical properties. The introduction of M2O5 (M = Nb, Ta)
was proved to be advantageous in mitigating the emulsification of CA6
material in the molten steel, and the increase in the densification of
emulsion layer could prevent CA6 materials from further steel corrosion and
penetration. The improved steel corrosion resistance of CA6 materials was
attributed to the optimization of the physical properties facilitated by the
formation of defects and the in situ phase. In addition, the reduction in
the wettability between the CA6 materials and molten steel served to
diminish the reactivity of the interface reaction. This work determined the
corrosion behaviour and corrosion mechanism of the CA6 materials in molten
steel and provided a new research route for designing CA6 materials with
improved corrosion resistance to molten steel.
Giant dielectric properties of CaCu3Ti4O12 ceramics synthesized by solid state reaction route
Authors: Kajal Parida A. , Kumar Pawan
Published: January 2024

CaCu3Ti4O12 (CCTO) ceramics were prepared by solid-state reaction route,
calcination at 1050?C for 4 h and sintering at 1050 and 1100?C for 8 h.
X-ray diffraction and Raman studies of the CCTO powders and sintered samples
confirmed the formation of single phase cubic structure with small amount of
CuO in the sintered ceramics. Scanning electron microscope study revealed
the average grain size between ~6 ?m to ~29 ?m in the CCTO ceramics sintered
at 1100?C. Room temperature giant dielectric constant (?r) of the order of
~105 with relatively low dielectric loss at 100Hz frequency was obtained in
the CCTO ceramics sintered at 1100?C. The present study has revealed that
grain size plays an important role in enhancing the dielectric properties of
CCTO ceramics.
Reaction sintering in compacted hydrolysed carbonated calcium phosphate
Authors: Zyman Zoltan , Epple Matthias , Goncharenko Anton , Tkachenko Mykola , Rokhmistrov Dmytro , Sofronov Dmytro , Orlov Herman
Published: January 2024

The thermal behaviour of the compact of an uncalcined hydrolysed carbonated
calcium phosphate powder slowly heated in air (i.e. under conditions of the
reaction sintering) was studied to reveal the reactions which could
influence its densification up to 1100?C. A number of different reactions
were found which occurred with different efficiency, but finally enabled a
densification of about 94%TD of the composite with a
hydroxyapatite/?-tricalcium phosphate (HA/?-TCP) ratio of 48/52. Such
composites are highly perspective for further densification under the
conventional or other suitable sintering methods at a desired temperature in
the production of improved HA/?-TCP ceramics.
Enhancing Al2O3-7A52 brazed joints by femtosecond laser surface machining of periodic alumina structure
Authors: Wang Haifeng , Zhang Deku , Wei Zhengbiao , Wang Kehong , Li Xiaopeng
Published: January 2024

In this study, we propose a method that utilizes femtosecond laser surface
machining technology to enhance the quality of ceramic-aluminium alloy
joints while minimizing residual stress. The present study investigates the
impact of the periodic structure of Al2O3 surface, which is machined using
femtosecond laser, on the properties of Al2O3-7A52 brazed joint. Various
surface periodic structures, including shallow grooves, deep grooves and
micro-convex platform, were created on the surface of Al2O3 using
femtosecond laser technology. The joint strengths of these different
periodic structures are 44.6, 49.1 and 41.1MPa, respectively, making 129%,
142% and 119% of the shear strength observed in the original planar
ceramic-aluminium alloy joint. By machining ceramic surfaces with
femtosecond lasers, a periodic structure can be created that enhances the
bonding area between the ceramics and solder. This increased surface area
improves the wettability of the solder to the ceramic surface, encouraging
diffusion reactions at the joint interface. Ultimately, this leads to the
creation of a solid bond with the ceramic interface, facilitated by the
formation of spinel (MgAl2O4).
In Vivo Inhibition of Dipeptidyl Peptidase 4 Allows Measurement of GLP-1 Secretion in Mice
Authors: Smits Mark M. , Galsgaard Katrine D. , Jepsen Sara Lind , Albrechtsen Nicolai Wewer , Hartmann Bolette , Holst Jens J.
Published: January 2024

Dipeptidyl peptidase 4 (DPP-4) and neprilysin (NEP) rapidly degrade glucagon-like peptide 1 (GLP-1) in mice. Commercially available sandwich ELISA kits may not accurately detect the degradation products, leading to potentially misleading results. We aimed to stabilize GLP-1 in mice, allowing reliable measurement with sensitive commercially available ELISA kits. Nonanesthetized male C57Bl/6JRj mice were subjected to an oral glucose tolerance test (OGTT; 2 g/kg glucose), and plasma total and intact GLP-1 were measured (Mercodia and Alpco ELISA kits, respectively). No GLP-1 increases were seen in samples taken beyond 15 min after the glucose load. Samples taken at 5 and 10 min after the OGTT showed a minor increase in total, but not intact, GLP-1. We then administered saline (control), or a DPP-4 inhibitor (valine pyrrolidide or sitagliptin) with or without an NEP-inhibitor (sacubitril), 30 min before the OGTT. In the inhibitor groups only, intact GLP-1 increased significantly during the OGTT. After injecting male C57Bl/6JRj mice with a known dose of GLP-1(7-36)NH2, peak GLP-1 levels were barely detectable after saline but were 5- to 10-fold higher during sitagliptin and the combination of sitagliptin/sacubitril. The half-life of the GLP-1 plasma disappearance increased up to sevenfold during inhibitor treatment. We conclude that reliable measurement of GLP-1 secretion is not possible in mice in vivo with commercially available sandwich ELISA kits, unless degradation is prevented by inhibition of DPP-4 and perhaps NEP. The described approach allows improved estimates of GLP-1 secretion for future studies, although it is a limitation that these inhibitors additionally influence levels of insulin and glucagon.

Article Highlights
COMERCIO Y CALIDAD DE LA INFRAESTRUCTURA LOGÍSTICA EN BOLIVIA
Authors: Romero Mamani Iván Jesús
Published: January 2024

Este estudio realiza un análisis del factor logístico en el volumen de comercio de Bolivia con el objetivo de obtener una medición cuantitativa del efecto global y desagregado por regiones. En una primera parte se analizan indicadores con el fin de evaluar la situación del sector logístico en Bolivia en relación con otros países de la región e identificar su posición relativa. Posteriormente mediante un panel de efectos mixtos aplicado al modelo de gravedad en el comercio, se demuestra la importancia de la mejora en la longitud de caminos asfaltados y las líneas de servicio móvil, (proxys del factor logístico interno), como componentes determinantes en el comercio exterior del país, asimismo este efecto es diferenciado considerando las regiones nacionales e internacionales, considerándose una contribución importante a la literatura existente, ya que incorpora elementos que no se tienen en cuenta en otros trabajos a nivel Bolivia.
LA CONSTRUCCIÓN DE PERSONAJES EN LA PRENSA ESCRITA BOLIVIANA: EL CASO DEL FEMINICIDA RICHARD CHOQUE FLORES
Authors: Laguna-Tapia Andrés , Rivera-Tapia Laura
Published: January 2024

Este artículo se centra en el análisis de la construcción noticiosa de personajes en la cobertura de violencia de género y feminicidios en la prensa escrita nacional, enfocándose en el caso de Richard Choque Flores, un violador, feminicida y asesino en serie que atrajo la atención de la prensa boliviana durante varios meses. La creación de "personajes" en la narrativa periodística ayuda a los lectores a comprender fenómenos perturbadores como los crímenes de género y permite a los periodistas desarrollar contenido más allá de la mera presentación de hechos. Se destaca el uso de retratos mítico-biográficos como estrategia narrativa, pero se señalan patrones sensacionalistas y estigmatizadores en la cobertura del crimen. El artículo aboga por un enfoque crítico y ético en la cobertura de la violencia de género y sugiere que la prensa debe evitar incurrir en violencia mediática. En última instancia, se enfatiza la importancia de abordar la violencia de género y su impacto en la sociedad de manera responsable y consciente en los medios de comunicación.
Derivas del sentido de la justicia rawlsiano como recurso de apoyo para la educación para la paz
Authors: Erives Chaparro César Akim , García-González Dora Elvira
Published: January 2024

El presente texto aborda el tema del sentido de la justicia en el constructo teórico de John Rawls. Este recurso es fundamental para lograr la cimentación de una sociedad justa, de modo que el sentido de la justicia permite dar cuenta de los sentimientos morales que, sin dejar de ser racionales, avalan conjuntamente situaciones de cooperación mutua y de solidaridad. Así, el sentido de la justicia se traza como un recurso relevante —planteado como virtud— que, al aparecer en las acciones morales, permite mostrar la importancia de la educación para establecer situaciones pacíficas.
experiência da escrita para uma construção cartográfica
Authors: Gonçalves Gabriela Walter , Santos Kátia Alexsandra dos
Published: January 2024

O objetivo deste trabalho foi discutir acerca da utilização de um dispositivo de pesquisa: o caderno digital itinerante, a partir do qual foi possível promover a construção conjunta de uma pesquisa, partindo do método cartográfico. A pesquisa de campo que deu origem a esta reflexão metodológica teve por objetivo principal cartografar experiências sapatão na cidade, por meio da construção conjunta de um caderno digital itinerante no qual as participantes, juntamente com a pesquisadora, escreviam sobre suas experiências como mulheres lésbicas e/ou pessoas que se reconheciam enquanto sapatão. Tendo como um dos instrumentos a análise do diário de campo, produzido durante a pesquisa, foi possível discutir em profundidade o enfoque metodológico adotado e questionar a dicotomia pesquisadora-objeto, provocando algumas reflexões acerca da temática da participação e do desenvolvimento de pesquisas on-line, sobretudo no período pandêmico. Por fim, apostar na cartografia enquanto método de pesquisa com e não sobre permitiu a produção de uma pesquisadora sapatão que pudesse se ocupar da escuta, lendo sobre diferentes processos de subjetivação e, com isso, produzindo outros sentidos para seu objeto de pesquisa.
SOBRE A CURRICULARIZAÇÃO DA EXTENSÃO NOS CURSOS SUPERIORES DO IFMT: UMA ANÁLISE DOS PERCURSOS E DESAFIOS
Authors: Ojeda Caroline Marins , Lopes Patrícia Pereira da Silva , Batista Vanessa
Published: January 2024

O artigo apresentado tem origem no projeto de pesquisa intitulado “Curricularização da Extensão: uma análise da implementação e sua indissociabilidade entre ensino, pesquisa e extensão no Instituto Federal de Mato Grosso”, de cunho qualitativo, em que se investigou a implementação da curricularização da extensão nos cursos superiores do IFMT. Utilizando um questionário, do qual obtivemos trinta e nove respostas de servidores da instituição que trabalham diretamente com cursos superiores – de um total de sessenta e dois cursos -, e reuniões com duas equipes de gestão de cursos de graduação do IFMT, analisamos o contexto desta instituição, partindo de uma proposta de problematização do processo de curricularização da extensão. Os resultados apontam para a necessidade da promoção de diálogos sobre as dificuldades do corpo docente e gestão de cursos na implementação da extensão no currículo, assim como para a importância da formação, visando a compreensão deste processo que se apresenta ainda incipiente na instituição.
Barriers in LIS Scholarship in India: Some observations
Authors: Roy Mantra , Chatterjee Sutapa
Published: January 2024

Although LIS research output, globally, has increased in recent years, why is there a dearth in LIS research from countries like India in the Global South? What barriers and challenges impede LIS researchers’ active participation in scholarly communications? Is there a bias against research output from the Global South? These are some of the questions that the author investigated with the help of ACRL’s Research and Scholarship Grant (2019 - 2020). The author collaborated with a librarian colleague in India at a second stage of the project to collect supplementary data. The second phase of the research was supported by the Marcia Tuttle International Travel Grant from NASIG (2020 - 2021). Important findings include the need for Open Access and training in academic writing standards which could help resolve some of the challenges. Learning from our Global South colleagues may assist with our work with international students and students from multiple backgrounds.
Impact of Transformative Agreements on Publication Patterns
Authors: Bakker Caitlin , Langham-Putrow Allison , Riegelman Amy
Published: January 2024

"Transformative agreements" are agreements made between publishers and institutions that were intended to transform the traditional subscription-based scholarly publishing system to open access. Some publishers and institutions have argued that these are the best option, yet, they are increasingly being called into question. Not only does the transition remain incomplete, they create negative effects on researchers without access to an agreement or funding to pay an article processing charge. This research project sought to address the question of whether transformative agreements increase the number of open access publications. In April 2022, we retrieved 370 transformative agreements from the ESAC Transformative Agreement Registry, of which 72 met our inclusion criteria. At that time, agreements in the ESAC Registry were heavily weighted towards Europe. We retrieved publications from the Web of Science Core Collection, and screened these to ensure that they were authored by researchers at participating institutions and published in hybrid open access journals covered by the agreement. Using the Unpaywall API, we determined the open access status of each item. Through this process, we identified 156,053 publications that met inclusion criteria. In this article, we examine changes in publication patterns at an aggregate level and per agreement.
Randomized Clinical Trial: Effectiveness of Tinnitus Treatment Using Music de Tinnitus Therapy Compared with Standard Therapy
Authors: Sutanegara Sari Wulan Dwi , Saputra Komang Andi Dwi , Putra I. Wayan Gede Artawan Eka , Suryatika Ida Bagus Made , Arthana I. Made Nudi
Published: January 2024

Background: Tinnitus is the perception of sound heard by a person without an external stimulus. Tinnitus can be divided into two, which tinnitus subjective and objective. About 10%–14.5% of the world’s population experience tinnitus. The management of tinnitus is still a challenge for researchers. Until now, there has been no effective management of tinnitus. The last therapy available is to make artificial sounds that imitate the tinnitus sound so that it can mask the actual tinnitus sound. In addition, Song therapy is expected to reduce the stress level of tinnitus patients.
Methods: This research uses a double-blind randomized clinical trial with stratified and matching risk factors from the sample then the sample is randomized to get 104 samples consisting of 52 control groups and 52 experimental groups. Both groups will be assessed objectively with the Tinnitus Handicap Inventory (THI), and Tinnitus Primary Function Questionnaire (TPFQ), and subjectively with the Visual Analog Scale (VAST) before and after using the application. Assessment is done using the google form. The control group will be given an application containing a sound generator and the experimental group will be given an application containing de tinnitus Song. Both groups used the app for 2 hours daily for 3 months. Song de tinnitus was obtained from previous studies.
Results: The difference in risk factors in the two groups was 0.01 and the data obtained to be tested is normally distributed with the Kolmogorov Smirnov test (Sig > 0.1). We used a significance level of 95% and a research power of 0.1 with the result that there was a difference between the control group and the experimental group, better on the experimental group test with Chi-Square THI (p ∼ 0.005), TPFQ (p ∼ 0.004) and VAST (p ∼ 0.002). THI (Relative risk reduction (RRR) = 59% Absolute risk reduction (ARR) = 25%, number needed to treat (NNT) = 4, TPFQ (RRR = 53.84%, ARR = 26.92%, NNT = 3.71) and VAST (RRR = 72.22%, ARR = 25%, NNT = 4).
Conclusion: We got better results using the app with de tinnitus Song (Music de Tinnitus) than using standard therapy.
Makna dan Fungsi Tradisi Upah-Upah dalam Masyarakat Desa Batas Kecamatan Tambusai Kabupaten Rokan Hulu
Authors: Nofrita Misra , Arianti Rita , Ningsih Asih Ria , Hermawan Hermawan , Nuratika Nuratika
Published: January 2024

In Rokan Hulu, there is a unique tradition called Upah-upah. This tradition is interesting to research because it is still used today which serves to restore the spirit. The aim of this study was to describe the form and function of the upah-upah tradition in Batas village. In this study the authors used qualitative methods. The steps for collecting data are, first, making observations regarding the selection of informants taken for research. Second, conduct interviews with informants regarding upah-upahs in Batas village by recording them. Third, transcribe the recording results. Fourth, process the data that has been transcribed and fifth, make an analysis of the results of the data that has been transcribed. The results of research on the meaning and function of the upah-upah tradition of the people of Batas Village, Tambusai District, Rokan Hulu Regency, concluded that the meaning contained in the upah-upah tradition is as a form of gratitude for what God has given, whether in the form of safety from disasters, after giving birth and when starting a new life. Apart from that, the function of the Upah-upah tradition for the people of Batas Village is, first, to restore enthusiasm. Second, provide self-confidence to people who are being paid. Third, welcoming and giving thanks for someone's life journey. Apart from that, wages are used as a tradition to restore or restore a person's enthusiasm, such as after an accident, after giving birth, wages after marriage, wages after completing a treatment, wages after graduating from college, and wages after graduating from college. finished circumcision.
Pengaruh Kegiatan Bermain Peran dalam Mengembangkan Kecerdasan Linguistik Anak Usia Dini
Authors: Fathia Wilda , Yuningsih Restu , Indriyani Vivi , Fitri Hani Melda Asrul
Published: January 2024

Linguistic intelligence is one aspect that must be stimulated and utilized appropriately from an early age. Because young children often imitate what they hear and see. However, not all children are optimal in developing their linguistic intelligence. Several things related to linguistic intelligence include being able to convey what is thought through verbal means in the form of words. Therefore, children's learning processes need to be modified by applying role-playing learning methods. This research aims to prove the application of role playing in improving children's linguistic intelligence. This type of research is an experiment with a one group pretest and posttest design. The data for this research are scores from observations of children's linguistic intelligence. The research results show that the application of role playing methods in learning is proven to be able to improve and develop the linguistic intelligence of young children.
IMPLEMENTASI KEBIJAKAN OTONOMI DAERAH TERHADAP LAJU PEMULIHAN EKONOMI PASCA COVID 19 DI WILAYAH SUMUT
Authors: Haikal Sinta Aulia , Marliyah Marliyah
Published: January 2024

This study aims to look at the implementation (role) and policies set by the North Sumatra regional government on several issues related to the Covid-19 virus, one of which is the decline in the regional economy and what steps the government has taken in terms of restoring the economy. The method used in this study is to use an analytical descriptive approach, while the data used are analytical qualitative data sourced from secondary data from the LKPJ Gubernur North Sumatera 2020 and primary data from valid references. Based on the results of the discussion in the implementation of regional autonomy policies on economic recovery, the regional government of North Sumatra and the Pemko Medan have implemented several strategic policies that can be implemented related to fiscal and monetary which are needed to provide stimulation for economic recovery. In addition, the Pemko Medan has also implemented policies to increase economic growth, one of which is collaborating with the North Sumatran Chamber of Commerce (KADIN) for the revival of UMKM as the backbone of regional development.
KARAKTERISTIK SISTEM INFORMASI AKUNTANSI MANAJEMEN DAN TEKNOLOGI INFORMASI TERHADAP KINERJA MANAJERIAL PADA HOTEL KOTA PEKANBARU
Authors: Riswandi Riswandi , Anriva Della Hilia , Suci Rama Gita
Published: January 2024

Penelitian ini bertujuan untuk mengetahui pengaruh Broad Scope, Timeliness, Aggregation, Integration dan Teknologi Informasi terhadap kinerja manajerial pada Hotel Bintang 3 di Peikanbarui. Metode penelitian kuantitatif ini menggunakan data primer yang diperoleh dari kuisioner. Populasi dalam penelitian ini adalah manajer weirei, manajer pemasaran, manajer operasional, manajer keuangan, dan manajer geineiral pada hotel bintang 3 di Peikanbarui. menentukan sampel penelitian ini dengan menggunakan sampel jenuh dan memperoleh kuesioner yang berjumlah 41 tanggapan. Analisis data dilakukan dengan menggunakan SPSS versi 24. Metode analisis data dalam penelitian ini adalah uji validitas dan reliabilitas, uji asumsi klasik, pengujian hipotesis melalui uji F dan uji t serta uji koefisien deiteiminasi (R2) . Hasil penelitian ini menunjukkan bahwa karakteristik sistem informasi akuntansi manajemen (cakupan luas, garis waktu, agregasi, integrasi) dan teknologi informasi mempunyai pengaruh yang signifikan terhadap kinerja manajerial
Application of Artificial Intelligence (Neural Networks) in Education
Authors: ZAKARYAN Arman
Published: January 2024

This article focuses on the use of artificial intelligence in the educational environment. We consider the latest technology, which already plays a huge role for both teachers and students. Currently, there are many systems for the development of training systems, among which artificial neural networks occupy a substantial place. The article presents an example of the use of artificial neural networks, which can play a significant role in developing educational systems.
GENERAL OBSERVATIONS ON THE PECULIARITIES OF V. SIRADEGYAN'S PROSE LANGUAGE AND VISUALIZATION TOOLS
Authors: Hovakimyan Hovhannes
Published: January 2024

ABSTRACT

The work analyzes the peculiarities of Vano Siradeghyan, who is one of the most outstanding prose writers of modern Armenian literature.This analysis utilizes the viewpoint of stylistic vocabulary. In addition, the opinions from other scholars are considered regarding the author.

Furthermore, the author’s use of lexicon and grammar, multilayered language are also discussed in this analysis. Lastly, a detailed study of Vano Siradeghyan’s prose is considered, the means of illustration used by him, the various methods by which the author received the literary text, the use of certain grammar and literary structure, and also the author's sophisticated word choices.
PENGARUH MOTIVASI KERJA TERHADAP KUALITAS KINERJA KARYAWAN UPTD KECAMATAN SANDAI
Authors: Ivanka Irna Dianis
Published: January 2024

Penelitian ini bertujuan untuk mengetahui: 1) Bagaimana motivasi kerja dapat mempengaruhi kualitas kinerja karyawan UPTD Puskesmas Sandai; 2) Bagaimana hubungan motivasi kerja dan kualitas kinerja karyawan UPTD Puskesmas Sandai. Jenis penelitian ini menggunakan metode Kuantitatif yaitu suatu penelitian yang bersifat menanyakan hubungan antara dua variabel. Populasi dalam penelitian ini adalah seluruh Pegawai UPTD Puskesmas Sandai sebanyak 110 pegawai. Dan dengan menggunakan teknik Random Sampling, maka jumlah sampel dalam penelitian ini sebanyak 52 responden diambil dari sebagian populasi yaitu dengan melakukan survei langsung ke objek atau sample penelitian. Teknik pengumpulan data menggunakan observasi, angket/kuesioner, serta dokumentasi. Hasil yang diperoleh dari penelitian ini adalah: 1) Motivasi berpengaruh singifikan terhadap kualitas kinerja karyawan, Hal ini diperkuat dan didukung oleh hasil uji T bahwa nilai sig 0,042 < 0,05. Selanjutnya dapat dilihat hasil dari t hitung > t tabel atau lebih besar yaitu 2,092 > 1,676 artinya Ho ditolak dan Ha diterima; 2) Hubungan motivasi kerja memiliki presentase yang rendah terhadap kualitas kinerja karyawan. Hal ini dibuktikan dari hasil uji determinasi yang menghasilkan nilai R square sebesar 0,284 (28,4%), dimana interval koefisien dari uji determinasi pengaruh motivasi terhadap kualitas kinerja pada penelitian ini berada pada interval 0,20-0,399.
MANAJEMEN STRATEGI DENGAN POLA KEMITRAAN PENJUALAN MOBIL BEKAS DI PONTIANAK
Authors: Harahap Rina Mandara
Published: January 2024

Tujuan penelitian adalah untuk mengetahui strategi bisnis perusahaan mobil bekas di Pontianak dan pola kemitraan perusahaan mobil bekas di Pontianak dalam pengembangan usaha. Temuannya adalah Penjual mobil bekas menggunakan strategi diferensiasi produk untuk membedakannya dari pesaing. Cara yang digunakan penjual tersebut berbeda-beda, diantaranya  dengan membuat kerjasama yang baik dengan penjual sparepart mobil, membuat bengkeng sendiri, hanya membeli mobil yang siap pakai, serta menyewa ruko untuk membuka dealer. Pola Kemitraan yang dilakukan oleh pedagang mobil bekas di Pontianak adalah pola keagenan, dimana agen diperbolehkan menjual mobil bekas kepada konsumen, dan aturan main dalam kemitraan tersebut adalah asas saling percaya yang disepakati saja.
ANALISIS PENGUASAAN TEKNOLOGI BISNIS DIGITAL DALAM KEUNGGULAN BERSAING REVOLUSI INDUSTRI 4.0 PADA UMKM KULINER DI KOTA PONTIANAK
Authors: Henirsa Putri , Verdianti Verdianti , Azimi Aulia
Published: January 2024

Persaingan di sektor bisnis saat ini sangat pesat dalam merebut persaingan pasar konsumen. Pemanfaatan teknologi memberikan banyak keunggulan bersaing bagi bisnis. Kemampuan untuk menguasai serta efektif memanfaatkan teknologi telah menjadi bentuk proses dalam meningkatkan nilai tambah  dalam membantu membangun reputasi bisnis yang bisa meningkatkan keunggulan bersaing. Penguasaan teknologi memungkinkan untuk menciptakan produk dan layanan yang lebih unggul, peningkatkan efisiensi operasional dan meraih pangsa pasar lebih besar dengan keterampilan memafaatkan teknologi menjadi kunci dalam meraih keunggulan bersaing di era Revolusi Industri. Penelitian ini bertujuan untuk mengetahui (1) Penguasaan teknologi digital dan bisnis UMKM sektor kuliner dalam upaya memperoleh keunggulan bersaing pada era Revolusi Industri 4.0 di Kota Pontianak. (2) Pemanfaatan teknologi digital dan bisnis UMKM sektor kuliner dalam upaya memperoleh keunggulan bersaing pada era Revolusi Industri 4.0 di Kota Pontianak. (3) Strategi Bersaing Bisnis di Era Revolusi Industri 4.0 pada pelaku usaha UMKM Sektor Kuliner di Kota Pontianak. penelitian ini menunjukkan bahwa : (1) Dalam menghadapi perubahan paradigma komunikasi, perusahaan kini berfokus pada implementasi layanan pelanggan yang adaptif terhadap dinamika pasar melalui saluran ritel digital. (2) Dalam era Revolusi Industri 4.0 di Kota Pontianak, UMKM sektor kuliner dapat meraih keunggulan kompetitif dengan memanfaatkan yeknologi digital dan strategi bisnis yang terintegrasi. (3) Dalam era Revolusi Industri 4.0 pelaku usaha UMKM sektor kuliner di Kota Pontianak perlu mengadopsi strategi keunggulan bersaing yang terus menerus untuk memenangkan persaingan yang ketat.
MANAJEMEN STRATEGI DALAM MEMINIMALISIR RESIKO INVESTASI DAN TRADING SAHAM SYARIAH PADA PLATFORM IPOT
Authors: Julianto Julianto , Hidayati Heny
Published: January 2024

Penelitian ini bertujuan untuk mengetahui manajemen strategi yang digunakan dalam meminimalisir resiko investasi dan trading saham syariah pada platform trading IPOT. Pendekatan yang digunakan dalam penelitian ini yakni menggunakan pendekatan kualitatif dengan metode studi literatur. Hasil penelitian menunjukan bahwa manajemen strategi dalam meminimalisir resiko investasi dan trading saham syariah pada platrform IPOT adalah, 1) Menggunakan modal/uang yang bersumber dari uang utama dengan porsi 10% dari gaji bulanan, hal ini akan meminimalisir kerugian saat grafik pergerakan saham mengalami penurunan yang tajam, sehingga uang utama yang 90% dapat mencukupi kebutuhan hidup harian, ini adalah konsep paling penting dalam trading. 2) Melakukan analisis teknikal dengan melihat grafik harga pada historis chart pergerakan sebelumnya termasuk indikator yang menjadi pemicu kenaikan maupun penurunan harga saham dan analisis fundamental dengan cara update berita ekonomi terbaru termasuk  laporan keuangan perusahaan untuk menghasilkan keputusan yang tepat dalam trading. 3) Menggunakan manajemen resiko seperti pada Stop loss dan take profit, posisi yang tepat saat masuk dan keluar (Buy and sell), dan manajemen modal seakurat dan sebaik mungkin sehingga saat mengalami kerugian dana tidak terkuras banyak. 4) Pengguna harus dapat menguasai dan mengendalikan emosi, mampu mengelola stres, dan menjaga disiplin dalam trading karna self control yang baik dapat membuatmu untuk tenang dalam mengampil keputusan secara rasional dalam trading. 5) Menghindari saham gorengan (baru listing melalui IPO) yang rentan menjadi mainan para bandar saham, hal ini dapat meminimalisir kerugian yang didapat.
Using photography in history of science and technology:
Authors: Pereira Hugo
Published: January 2024

Photography has been used to record different features of human societies since its invention in the first half of the nineteenth century. After years of being used as an illustrative tool in history, photography conquered its place as a primary source since the mid-1980s. In this article I add to this debate with a methodological approach to use photography in history of science and technology (including medicine and engineering). I argue that photography offers an exclusive view to understanding how science and technology were implemented, used, represented, and presented to the public. I offer both practical guidelines and a theoretical framework, based on Barthesian semiotics, which can be used by younger as well as by more experienced academics. I claim that this proposal has the potential to be used as a common denominator between assorted photographic collections and therefore to allow broader comparisons across different historical and geographic contexts. Moreover, it promotes the critical view of photography that should not be taken by its face value, but it should be understood within its sociotechnical and technoscientific context. This reflection certainly has its flaws and shortcomings, and it is naturally open to improvements, through its practical application to photographic collections.
Propuesta de criterios metodológicos para la interpretación histórica desde la fotografía y su análisis documental
Authors: Olivera Zaldua Maria , Salvador Benítez Antonia , Sánchez Vigil Juan Miguel
Published: January 2024

El uso de la fotografía en la investigación histórica es aún objeto de controversia y debate por los investigadores, asignatura pendiente que requiere del consenso en cuanto a su valor científico como documento. La metodología en lo que se refiere a este aspecto suele reducirse a los planteamientos generales, sin profundizar en la fuente y su tipología, por ello es objeto de este artículo proponer nuevos criterios metodológicos a tener en cuenta en la investigación histórica de la fotografía, de manera que sirvan para comprobar y validar contenidos, justificar hipótesis, y en definitiva elevar la calidad científica de la investigación. La propuesta que se realiza se basa en casos prácticos ya difundidos, y por tanto en la experiencia, con el nexo común de la relevancia de los mismos para el estudio histórico desde la fotografía. Como resultado se aportan varios criterios sobre análisis documental, y un decálogo general para la comprobación y validación de contenidos desde las fuentes.