bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluación de seguridad del ácido benzoico complejado empleando ensayos de permeación in vitro con piel de cerdo en celdas de Franz
Authors: Martínez Laura Alejandra , Sanabria Lina Marcela , Baena Yolima
Published: August 2020

Las celdas de Franz son una de las herramientas para evaluar la permeación transepitelial de compuestos mediante la realización de ensayos in vitro, estos permiten inferir el comportamiento de seguridad de un compuesto en la piel. El objetivo de esta investigación fue determinar el comportamiento de permeación del ácido benzoico a partir de complejos con polielectrolitos () en comparación con el ácido benzoico sin complejar, para inferir su comportamiento de seguridad. En una primera fase, se establecieron las condiciones de almacenamiento de la piel comparando los parámetros de difusión (flujo y constante de permeación) y pérdida de agua transepitelial, empleando piel de orejas de cerdos recién sacrificados, almacenadas en NaCl 1M a -2°C por 3 días; se trabajó bajo condiciones de dosis infinitas. Posteriormente, se realizó el ensayo de permeación de dos complejos entre ácido benzoico y Eudragit E, en comparación con el ácido benzoico, bajo condiciones de dosis finitas. La cuantificación del ácido benzoico fue realizada con un método analítico validado por HPLC-DAD. Los resultados evidenciaron que las muestras biológicas pueden almacenarse durante 72 h en las condiciones descritas. El comportamiento de permeación del ácido benzoico complejado respecto al ácido benzoico libre demostró tener un mejor perfil de seguridad, puesto que hubo una menor permeación para el primer caso. Estos resultados demuestran que la complejación del ácido benzoico podría disminuir las reacciones de sensibilidad que normalmente este presenta, basándose en la disminución de su permeación.
Talinum paniculatum leaves with in vitro antimicrobial activity against reference and clinical strains of Staphylococcus aureus interfere in oxacillin action
Authors: Cerdeira Cláudio Daniel , Da Silva Jeferson J. , R. Netto Manoel F. , G. Boriollo Marcelo F. , Santos Gérsika B. , C. dos Reis Luis F. , P. L. Brigagão Maísa R.
Published: August 2020

Propose: We evaluated the antibacterial potential of the crude leaf extract (CLE) and fractions hexane (HX) and ethyl acetate (EtOAc) from Talinum paniculatum alone and in association with oxacillin (OXA) against OXA-resistant Staphylococcus aureus (ORSA, environment isolates) and OXA-sensitive S. aureus (OSSA, ATCC 25923). Furthermore, toxicity tests were performed. Methods: The antibacterial activity was evaluated through checkerboard assay (broth microdilution) to establish the minimum inhibitory (MIC) and minimum bactericidal concentrations (MBC). Toxicity test in mice was assessed. Results: The MIC values for the CLE and its fractions against ORSA and OSSA were in the order of HX (500 μg ml–1) = EtOAc < CLE (4000 μg ml–1). EtOAc and HX presented outstanding antibacterial activities against ORSA, and these fractions were bactericidal toward OSSA. Conversely, the associations between plant product (CLE, EtOAc, or HX) and OXA exhibited no synergistic effects. During these associations, there was an increase in OXA MICs anywhere from 2- to 4092-fold. The CLE presented absence of toxicity at a dose of 5 g kg-1 (in vivo). Conclusion: Although T. paniculatum be a good source of bioactive compounds with antistaphylococcal potential, the researchers should be cautious, since its edible leaf may interfere with OXA therapy (mitigating OXA-induced growth inhibition or killing of S. aureus and enhancing S. aureus resistance).
EGFR and HER2 small molecules inhibitors as potential therapeutics in veterinary oncology
Authors: Cadena García Juan Martín , Giraldo Murillo Carlos Eduardo , Ramos Jaramillo Manuela
Published: August 2020

EGFR and HER2 receptors are crucial signaling molecules tyrosine kinase involved in human cancer. Aberrant signaling is associated with a variety of cancers, frequently with poor prognosis. Currently, EGFR and HER2 receptors are being targeted by small molecules, which offer a huge benefit to those patients afflicted by aggressive forms of cancer, improving their prognosis. Both human and canine cancers share molecular, biological, histopathological and clinical similarities, including EGFR and HER2 expression in some forms of cancer. However, despite the use of one tyrosine kinase inhibitor approved to treat canine mastocytoma, canine cancers overexpressed EGFR and HER2 do not yet have targeted therapy, leading to high morbidity and mortality. Targeting EGFR and HER2 receptors in canine cancers using comparative approaches in human cancer could lead to better outcomes.
The selective obtaining of amyrins from Amazonian Protium oleoresins
Authors: Gomes da Silva Ferreira Rosilene , Guilhon-Simplicio Fernanda , De Lima Yamaguchi Klenicy Kazumy , Duarte de Lira Priscila , Marques Machado Tallita , Couto Ferreira Márcio Antônio , Da Veiga Júnior Valdir Florêncio , Silva Lima Emerson
Published: August 2020

The oleoresin produced by species of genus Protium sp. is rich in alpha and beta-amyrins, two triterpenes with many pharmacogical activities. Considering the need to make the improved obtainment of these products feasible, this study sought to optimize techniques for the extraction and isolation of amyrins from resin. Two methods of extraction (maceration and sonication) with different solvents were compared to direct isolation from crude resin. The isolation of triterpenes was performed by chromatographic columns and the yields of extracts and fractions were analyzed by analysis of variance. The best extraction solvent for amyrins was hexane for both maceration and sonication methods (38.16±2.06% and 37.67±8.21%, respectively). There was no statistical difference between these methods and the direct method (32.05±2.40%). Additionally, the direct method is cheaper and more environmentally friendly. Thus, this study showed that it is possible to obtain a large quantity of amyrins by means of cheap, fast and ecological methods.
Régimen jurídico de las recetas médicas en España e Iberoamérica
Authors: Bombillar Sáenz Francisco Miguel
Published: August 2020

Esta contribución se ocupa de uno de los ejes sobre los que se articula la prestación farmacéutica en nuestro sistema sanitario: la receta médica. En este artículo se abordan las notas más relevantes que caracterizan el régimen jurídico de la receta médica en España y en Latinoamérica: concepto, tipos, reconocimiento por otros estados, identificación de fármacos por la denominación común internacional, objeción de conciencia del farmacéutico, receta médica electrónica o atención farmacéutica.
Using Copula Functions to Estimate The AUC for Two Dependent Diagnostic Tests
Authors: Bravo Melo Luis Carlos , Portilla Yela Jennyfer , Tovar Cuevas José Rafael
Published: August 2020

When performing validation studies on diagnostic classification procedures, one or more biomarkers are typically measured in individuals. Some of these biomarkers may provide better information; moreover, more than one biomarker may be significant and may exhibit dependence between them. This proposal intends to estimate the Area Under the Receiver Operating  Characteristic Curve  (AUC)  for classifying individuals in a screening study. We analyze the dependence between the results of the tests by means of copula-type dependence (using FGM and Gumbel-Barnett copula functions), and studying the respective AUC under this type of dependence. Three different dependence-level values were evaluated for each copula function considered. In most of the reviewed literature, the authors assume a normal model to represent the performance of the biomarkers used for clinical diagnosis. There are situations in which assuming normality is not possible because that model is not suitable for one or both biomarkers. The proposed statistical model does not depend on some distributional assumption for the biomarkers used for diagnosis procedure, and additionally, it is not necessary to observe a strong or moderate linear dependence between them.
Aplicación de modelos lineales mixtos para estudiar la producción de leche en vacas de la raza Lucerna
Authors: González Herrera Luis Gabriel , Hernández Barajas Freddy
Published: August 2020

A Colombia se le considera como un país muy diverso y con múltiples opciones productivas a nivel ganadero. La raza colombiana Lucerna se caracteriza por presentar buenos desempeños productivos y reproductivos en el trópico bajo de Colombia, debido a su buena rusticidad. Existen pocos estudios que permitan identificar las ventajas productivas que se pueden obtener, al utilizar este tipo de animales. El estudio de la producción de leche por día es una herramienta importante para evaluar la eficiencia de un hato lechero; esta variable es afectada por factores genéticos y no genéticos. Entre tanto, la evaluación de Condición Corporal (CC) por ejemplo, ha sido propuesta como herramienta en el manejo nutricional, reproductivo y de salud en hatos bovinos, por ser un buen indicador del estado nutricional de la vaca y por ende, del nivel de desempeño que pueden tener las hembras para producir leche durante la lactancia. En la presente investigación se utilizaron los registros productivos de 197 bovinos colombianos sintéticos de la laza Lucerna y sus cruces, procedentes de una empresa agropecuaria ubicada en el Valle del Cauca, Colombia. La variable producción de leche por día fue modelada en función del componente racial, la edad de la vaca al momento del parto y la condición corporal. Para la construcción de los modelos fue utilizada una estrategia incremental, iniciando con un modelo lineal clásico con efectos fijos, agregando posteriormente efectos aleatorios y terminando con la modelación de la varianza y las correlaciones entre las observaciones para cada animal. Para identificar el modelo con el mejor ajuste, se utilizaron la prueba de razón de verosimilitud y el criterio de información de Akaike. El modelo que mejor se ajustó para explicar la producción de leche por día fue el que incluyó la variable condición corporal, la edad de la vaca al momento del parto y un término cuadrático de la edad. El modelo estimado acompañó bien la evolución de la producción de leche por día a lo largo de las lactancias, adicionalmente, el coeficiente de correlación de Pearson entre el valor real y el valor estimado fue de 0.792. Los supuestos del modelo se cumplieron satisfactoriamente. Las mayores producciones de leche fueron observadas para vacas con condición corporal alta y edades al parto entre los 100 y 150 meses
El modelamiento en la floricultura
Authors: Arredondo Hoyos Angie Katherine , Castañeda-Sánchez Darío
Published: August 2020

El modelamiento en la agricultura, con el desarrollo de las computadoras, cada vez cobra mayor importancia, no solamente para el monitoreo de las variables de estado del sistema, sino también en los procesos de toma de decisiones y gestión de este. El objetivo de este trabajo fue el de efectuar una revisión en torno a la evolución del modelamiento en la agricultura. Se partió de las propuestas de modelos de crecimiento y desarrollo clásicos, las cuales sentaron las bases para las estrategias de los modelos funcionales y estos dos a su vez para las modernas metodologías implementadas en el modelamiento dinámico. Se finaliza con un resumen de las estrategias y variables de estado para las cuales se reportan propuestas de modelos en el cultivo del crisantemo.
Procesos de modelación matemática en formación de profesores de matemáticas
Authors: Forero Poveda Alberto
Published: August 2020

El presente artículo expone las generalidades de algunas experiencias en el marco de los procesos de modelación de fenómenos reales, analizando qué aspectos potencian la formación de estudiantes para profesor de Matemáticas de la Universidad Distrital Francisco José de Caldas, igualmente pretende manifestar heurísticas asociadas a la resolución de problemas en el marco de la comprensión y caracterización de algunos fenómenos en contexto, interpretando recursos y herramientas que apoyan el trabajo de los estudiantes para profesor y permiten fortalecer el desarrollo de su pensamiento matemático. Después de realizar una introducción, el artículo presenta una contextualización del estudio, donde se describe la metodología y una caracterización de los procesos de modelación matemática que promovieron el análisis de las experiencias. Finalmente se establecen algunas conclusiones asociadas con diferentes elementos presentes en las experiencias, que permiten postular aspectos de interés para la formación de profesores de matemáticas en la actualidad.
Sistem Kekuasaan dan Budaya Masyarakat Sipil dalam Pengelolaan Limbah: Perspektif Pengelolaan Limbah di Tokyo
Authors: Mustapa Hasan , Yasyfina Siti , Azhar Ahmad , Nurmayanti Alfredes , Ruhenda Ruhenda
Published: August 2020

Perkembangan ekonomi, industrialisasi dan peningkatan jumlah penduduk, khususnya di Tokyo menimbulkan persoalan sampah di Jepang pada tahun 1950-an. Sebagai solusi atas masalah ini, pemerintah Jepang menerapkan praktik pengelolaan limbah padat, termasuk promosi 3R, pengumpulan terpisah, fasilitas insinerator limbah di wilayah perkotaan, pemulihan energi efisiensi tinggi, daur ulang abu insinerator, dan pembuangan akhir. Artikel ini bertujuan untuk mengetahui apakah solusi yang ditawarkan memiliki konsekuensi yang tidak terduga dan bagaimana sejumlah elemen masyarakat bereaksi terhadapnya. Karya ini menggunakan pendekatan kuantitatif dengan penerapan Q-Methodology. Temuan masalah menunjukkan terdapat empat tipe orang dan keyakinan inti, yakni: (a) Keyakinan inti super otoriter yang ditunjukkan oleh Ilmuwan yang mendukung pemerintah, (b) Keyakinan inti egaliter dengan pada masyarakat sipil yang berpandangan ekstrim, (c) Keyakinan sentral yang relatif egaliter, ditunjukkan oleh masyarakat sipil yang setuju dengan pemerintah, (d) Nilai individualistis inti otoriter yang tercermin pada perusahaan swasta yang bekerja untuk pemerintah.
Задачі зв’язності для узагальнених гіпергеометричних многочленів Аппеля
Authors: Luno Nataliia
Published: August 2020

В статті використано загальний підхід до розв’язування задач зв’язності для многочленів Аппеля, який базується на тому, що відношення трансферних функцій, які представляють собою формальні степеневі ряди, даних двох сімейств многочленів Аппеля є відомим рядом. Використовуючи рекурентні формули для знаходження коефіцієнтів ряду, який є відношенням двох даних формальних степеневих рядів, ми отримали розв’язок оберненої задачі для узагальнених гіпергеометричних многочленів Аппеля.  В загальному випадку розв’язок визначається рекурентними формулами, але у деяких часткових випадках, коли породжуюча функція має простий вигляд, розв’язок оберненої задачі виражається у замкнутій формі, зокрема, для многочленів Гоулда-Хоппера, або для узагальнених гіпергеометричних многочленів Аппеля, породжуюча функція яких співпадає із функцією Бесселя першого роду.
Користуючись цим же методом і відомим представленням узагальнених гіпергеометричних многочленів Аппеля у формі звичайного диференціального оператора, ми знайшли рекурентні формули розв'язку задачі зв'язності між узагальненими гіпергеометричними многочленами Аппеля та многочленами Бернуллі, між узагальненими гіпергеометричними многочленами Аппеля - многочленами Гоулд-Хоппера та між двома різними сімействами узагальнених гіпергеометричних многочленів Аппеля. Використовуючи схожий підхід, ми отримали нове рекурентне рівняння для  узагальнених гіпергеометричних многочленів Аппеля, коефіцієнти якого визначаються рекурентно, і встановили замкнуту форму декількох перших з них. Частковими випадками отриманого рівняння є, зокрема, відомі рекурентні рівняння для многочленів Гоулда-Хоппера і для многочленів Ерміта.
Крім того, розв'язок задачі зв'язності для двох різних сімейств узагальнених гіпергеометричних многочленів Аппеля отримано в іншій формі - з використанням значень цих многочленів в нулі.
Study related knowledge management process at the university department: theoretical approach
Authors: Misiūnaitė - Bačiauskienė Eglė , Jucevičienė Palmira
Published: August 2020

Educating professionals for knowledge organizations becomes a relevant goal of education. The underlying asset of knowledge organizations is unique knowledge possessing the essential worth for organizations’ value creation. In the dynamic structure of professionals’ competences the abilities of organizational learning are fundamental. Thus knowledge management increasingly becomes the paradigm uniting education and management. In this context universities identify themselves as knowledge organizations, the basic structural units of which – departments – have to distinguish themselves in the essential features of knowledge management if they wish to be able to educate future professionals for knowledge organizations. As research publications on studies related to knowledge management process at the university department are missing, modelling of such knowledge management process is a relevant research problem, which presupposes the question: what aspects of studies related knowledge management process are characteristic of the university department?This article provides a theoretical rationale for study related knowledge management process at the university department.

As a result of research literature analysis, the following conclusions have been drawn:

• The paradigm of knowledge management expands the concept of study related performance of the university department by adding the concept of study related knowledge management process.

• The concept of organizational learning as learning on individual and collective levels as well as at their interface, which creates organizational knowledge for empowering the construction, implementation and development of study programmes, is insufficientfor encouraging indepth changes of study related performance that respond to the challenges of the contemporary universit y.

• The process of study related knowledge management process is defined as an integrated whole of activities initiated and (or) supported at the university department for the sake of identifying, acquiring, creating, disseminating study related knowledge, storing valuable knowledge and applying it in studies. Organizational learning and its empowerment are of special importance in the process of study related knowledge management.
High-quality studies - vision of students of pedagogy
Authors: Žibėnienė Gintautė , Barkauskaitė Marijona
Published: August 2020

The development of national study quality assurance systems, discussions about study quality is an important step towards the implementation of lifelong learning and Bologna process targets, priorities. Students of the Higher Education are important element in study quality assurancesystem. It is written in the Republic of Lithuania Law on Science and Studies (2009) 41 paragraph: that „any high school must continuously update website and use other social media sites to update precise quantitative and qualitative information about <...> attitude of students, graduate students and other interested parts on quality of studies”. The twenty-first century universities emphasize the attention on students, quality of studies which became an asset and are associated with competitiveness and expectations of successful future.The aim is to present the first-year student’s of pedagogy opinion, vision about high quality studies. The research instrument is the questionnaire in writing from with open and closed questions. The research was with 198 first-year students of pedagogy (2012–2013) from Lithuanian University of Educational sciences and students of pedagogy from Vilnius Pedagogical College.First-year students of pedagogy were chosen because their expectations do not rely yet on the prior learning experience. The survey was taken of the general methodological guidelines, voluntary participation, participants selected a convenient time and the fundamental principles of the survey. To participate in the survey was available in two ways: remote and writing at university.
THE ANALYSIS OF AMERICAN FOOTBALL PLAYERS’ COURAGE LEVELS AND SPORT MENTAL THOUGHNESS
Authors: GÜVENDİ Burcu , GÜÇLÜ Mehmet , TÜRKSOY IŞIM Ayşe
Published: August 2020

The purpose of the present study is to examine the courage and mental toughness of elite Turkish male American football players. The study group consists of 231 American football players, with a mean age of 22.14±3.67 year and with a sports experience of 3.29±2.43 year. As data collection tool, ‘Personal Information Form’ ‘Mental Toughness Scale’ and ‘Sport Courage Scale’ were conducted face to face with the participants. For data analysis, descriptive statistics, t test, ANOVA and Pearson Correlation analysis were used. It was observed that there is a significant positive relation between sub-dimensions of mental toughness scale and sub-dimensions of courage scale. It was understood that there is a significant difference in all sub-dimensions of mental toughness based on age and competence-mastership, hardiness and being self-giving sub-dimensions of courage in sports scale in favor of sportspeople who are 24 years old or older. When it was evaluated based on sports year, there was a significant difference in favor of players doing sports for 5 years and more in the trust and continuity sub-dimensions of mental toughness scale and competence-mastership, determination and hardiness sub-dimensions of courage in sports scale. There was a significant difference in favor of players doing sports for 3 years and more in the trust and continuity sub-dimensions of mental toughness scale and competence-mastership and hardiness sub-dimensions of courage in sports scale, when it was evaluated based on the working time of the players with their coaches. Based on American football players’ playing at national team, it was clear that there was a significant difference in all sub-dimensions of courage in sports scale in favor of the sportspeople playing at national team. It was observed that mental toughness and courage in sports levels increase as the ages, years doing sports, the time of working with a coach of the American football players increase.
Focus group methodology for Doctor Who viewing behaviors v1
Authors: Gunderman Hannah
Published: August 2020

This protocol is a description of how Hannah Gunderman facilitates her focus groups around Doctor Who episodes in order to better understand how viewers perceive messages of empathy, geography, and social themes in the episodes. In this example, Hannah describes her focus group protocol for the Doctor Who episode "Vincent and the Doctor" (Series 5, episode 10). This protocol is meant to demonstrate how the protocols.io platform can be used to document workflows and methods within humanities researcher, showing how the platform can be for any researcher regardless of domain area.
Enzyme linked immunosorbent assay for investigating the binding of Streptococcal Protein-G (SpG) to diverseimmunoglobulins v1
Authors: A Justiz-Vaillant Angel
Published: August 2020

This SpL ELISA can be used to detect specific antibodies in various animal species including human, mouse, rat, dog, rabbit, chicken, monkey, pig and hamster [1]. 1. De Chateau M, Nilson BH, Erntell M, Myhre E, Magnusson CG, Akerstrom B et al. On the interaction between protein L and immunoglobulins of various mammalian species. Scand J Immunol 1993; 37: 399−405
Enzyme linked immunosorbent assay for investigating the binding of protein-LG (SpLG) to immunoglobulins. v1
Authors: A Justiz-Vaillant Angel , McFarlane-Anderson Norma
Published: August 2020

This SpLG ELISA can be used to detect specific antibodies in various animal species including human, mouse, rat, dog, rabbit, chicken, monkey, pig and hamster [1]. 1. Kihlberg BM, Sjöbring U, Kastern W, Björck L. Protein LG: a hybrid molecule with unique immunoglobulin binding properties.J Biol Chem. 1992;267(35):25583-25588.
Enzyme linked immunosorbent assay for investigating the binding of chemically prepared protein-LAG-anti-IgY (SpLAG-anti-IgY) to avian and mammalian immunoglobulins. v1
Authors: A Justiz-Vaillant Angel , McFarlane-Anderson Norma
Published: August 2020

This SpLAG-anti-IgY ELISA can be used to detect specific antibodies in various animal species including human, goat, donkey, mouse, rat, dog, cow, horse, ostrich, duck, pigeon, bantam hen, rabbit, chicken, monkey, pig, hamster, and many birds, wild and zoo animals species [1]. 1. Vaillant AJ, McFarlane-Andersonv N, Wisdom B, Mohammed W, Vuma S, et al. (2013) Immunoglobulin-binding Bacterial Proteins (IBP) Conjugates and their Reactivity with Immunoglobulin in Enzyme-Linked Immunosorbent Assays (ELISA). J Anal Bioanal Tech 4: 175. doi:10.4172/2155-9872.1000175
Competitive enzyme-linked immunosorbent assay for investigating SpL binding to mammalian and avian immunoglobulins v1
Authors: A Justiz-Vaillant Angel
Published: August 2020

This ELISA was based on the theory that antibodies present in different samples would compete with human IgG for binding to SpL, resulting in inhibition of human IgG-SpL interactions [1]. Reference: 1. Justiz-Vaillant AA, Akpaka PE, McFarlane-Anderson N, Smikle MF. Comparison of techniques of detecting immunoglobulin-binding protein reactivity to immunoglobulin produced by different avian and mammalian species.West Indian Med J. 2013;62(1):12-20.
A Graph-Learning Approach for Detecting Moral Conflict in Movie Scripts
Authors: Hopp Frederic René , Fisher Jacob Taylor , Weber René
Published: August 2020

Moral conflict is central to appealing narratives, but no methodology exists for computationally extracting moral conflict from narratives at scale. In this article, we present an approach combining tools from social network analysis and natural language processing with recent theoretical advancements in the Model of Intuitive Morality and Exemplars. This approach considers narratives in terms of a network of dynamically evolving relationships between characters. We apply this method in order to analyze 894 movie scripts encompassing 82,195 scenes, showing that scenes containing moral conflict between central characters can be identified using changes in connectivity patterns between network modules. Furthermore, we derive computational models for standardizing moral conflict measurements. Our results suggest that this method can accurately extract moral conflict from a diverse collection of movie scripts. We provide a theoretical integration of our method into the larger milieu of storytelling and entertainment research, illuminating future research trajectories at the intersection of computational communication research and media psychology.
New Formats, New Methods: Computational Approaches as a Way Forward for Media Entertainment Research
Authors: Breuer Johannes , Wulf Tim , Mohseni M. Rohangis
Published: August 2020

The rise of new technologies and platforms, such as mobile devices and streaming services, has substantially changed the media entertainment landscape and continues to do so. Since its subject of study is changing constantly and rapidly, research on media entertainment has to be quick to adapt. This need to quickly react and adapt not only relates to the questions researchers need to ask but also to the methods they need to employ to answer those questions. Over the last few years, the field of computational social science has been developing and using methods for the collection and analysis of data that can be used to study the use, content, and effects of entertainment media. These methods provide ample opportunities for this area of research and can help in overcoming some of the limitations of self-report data and manual content analyses that most of the research on media entertainment is based on. However, they also have their own set of challenges that researchers need to be aware of and address to make (full) use of them. This thematic issue brings together studies employing computational methods to investigate different types and facets of media entertainment. These studies cover a wide range of entertainment media, data types, and analysis methods, and clearly highlight the potential of computational approaches to media entertainment research. At the same time, the articles also include a critical perspective, openly discuss the challenges and limitations of computational methods, and provide useful suggestions for moving this nascent field forward.
Faktor-Faktor yang Memengaruhi Komitmen Generasi Z terhadap Pancasila
Authors: Primahendra Riza , Sumbogo Tri Adi , Lensun Reney Aquino , Sugiyanto Sugiyanto
Published: August 2020

This study intended to identify the influence of Generation Z’s perceptions on political parties and political education by mediating political leadership on the commitment to Pancasila. The study used a Partial Least Square Structural Equation Modeling (PLS-SEM) approach. The population was high school students in Jakarta. The sample was 82 students in XI grade. The results showed the perception of political parties influenced the views of political leadership (0.627). Perceptions of political parties influenced Pancasila’s commitment (0.357). The strongest influence was found to be in political education on the commitment of the Pancasila (0.722). Political education did not influence the views of political leadership (-0.009). The view of political leadership did not influence the commitment of the Pancasila (-0.194). The view of political leadership was not a factor influencing generation Z’s commitment to Pancasila. Generation Z’s commitment to Pancasila was influenced by two factors, namely political parties and political education. Political education was the highest factor influencing generation Z’s commitment to Pancasila.
KEARIFAN LOKAL ARSITEKTURE RUMAH ADAT OSING DALAM PEMBELAJARAN IPS
Authors: Zulfikar Fachri
Published: August 2020

This study described the local wisdom of Osing community as reflected on the architecture of traditional houses that could be used as instructional resources for social studies. The approach in this research was qualitative. Data were collected through observation and literature studies of books, journals, papers, written texts, and others related to the local wisdom and social studies education. This study shows that the architecture of the Osing traditional house has specific values that can be used for instructional purpose of social studies education.  Students could visit Kemiren village and learn directly from the architerture of the traditional house and other artifacts in the village.
Procesos de autorregulación del aprendizaje y desempeño académico en estudiantes de pregrado bajo la modalidad virtual
Authors: Mora Yate Claudia Tatiana Tatiana , Mahecha Escobar Jenny Consuelo , Conejo Carrasco Francisco
Published: August 2020

En el contexto educativo virtual, los procesos de autorregulación del aprendizaje juegan un papel muy importante por cuanto, son una herramienta que permite al estudiante alcanzar sus logros académicos. En este artículo se analiza la relación entre los procesos de autorregulación del aprendizaje y el desempeño académico de los estudiantes de licenciatura en pedagogía infantil en la asignatura de antropología social y cultural en una Universidad privada. Este estudio se desarrolló bajo un enfoque metodológico de tipo cualitativo, diseño descriptivo con un grupo de interés conformado por 10 estudiantes y 2 docentes. Los resultados indican que los factores de autorregulación del aprendizaje potenciadores del desempeño académico son la motivación, las estrategias pedagógicas y el autoconcepto, asimismo, se logró determinar que, aunque los estudiantes cuentan con procesos de autorregulación del aprendizaje estos se deben potenciar.
Actividades lúdicas en las clases de español como lengua extranjera
Authors: Hernandez Chirinos de Jesus Ramon Antonio , Silva de Jesus Hernández Francisco Das C
Published: August 2020

El presente trabajo, tiene como objetivo valorar las actividades lúdicas socializadas en las clases de español como lengua extranjera. La investigación se orientó desde una metodología cualitativa que busca generar procesos de comprensión de la realidad, en las que está inmersa la población; para ello, se conformó un grupo con estudiantes del primer año de educación media en una escuela pública de Brasil, cuyas edades oscilaban entre 14 y 20 años. En el estudio se aplicaron como instrumentos, el guión de entrevista y la observación no participante. Los resultados evidencian el papel que cumplen las actividades lúdicas como estrategias pedagógicas para fortalecen las clases de español como lengua extranjera. Se concluye que dichas actividades permiten a los estudiantes un disfrute de la asignatura, consolidándose la adquisición de la lengua con el uso de vocabulario y su puesta en práctica en un contexto real.
THE EFFECTIVENESS OF TWO STAY TWO STRAY, SOMATIC, AUDITORY, VISUALIZATION, INTELLECTUALLY, AND AUDITORY LEARNING TO IMPROVING NUMERICAL ABILITY
Authors: Huda Syamsul , Munifah  , Syazali Muhamad , Rahayu Syarifah Sri , Umam Rofiqul
Published: August 2020

Purpose of the study: This study was conducted to determine the effect of the TSTS (Two Stay Two Stray) learning model, SAVI (Somatic, Auditory, Visualization, and Intellectually), and AIR (Auditory, Intellectually, Repetition) on the numerical abilities of students. The purpose of the study is to determine the effect of three models: TSTS, AIR, and SAVI. Methodology: Type research used in this study is quantitative research. The type of experiment used in this study is quasi-experimental method; the hypothesis test used is the one-way ANOVA test. Main Findings: The result of the research revealed that the data if TSTS combine with SAVI models there is no difference to increase the numerical abilities, but if one of TSTS or SAVI combines with the AIR model will give the best improvement to develop numerical abilities. Applications of this study: It can be implemented in the scope of education, educators or teachers can choose the right learning model adapted to the curriculum to improve the numerical abilities of students. This research can provide input in choosing the right model for the learning process with the applied curriculum. Provide an overview of the impact of each learning model used in influencing student abilities. Because in each learning model has advantages and disadvantages of each. Novelty/Originality of this study: The novelty of this study is to determine an effective learning model for students' numerical abilities. The learning model is the Two Stay Two Stray Learning, Somatic Auditory Visualization Intellectually Learning, and Auditory Intellectually Repetition learning models. Based on this research the reader can determine an effective learning model used to determine students' numerical abilities. The curriculum used is the 2013 curriculum. The application of learning models in the curriculum helps the learning process take place and improves students' numerical abilities.
Reacción diagnóstica del embarazo en el Bufo Marinus con Gonadotropinas Séricas
Authors: De Castro Gómez Francisco , Isaza González Javier
Published: August 2020

Existe toda una gama de métodos cientificos unos, pseudocientificos otros, basados los primeros en los cambios que determina el huevo en el organismo de la gestante.
Traumatismo obstétrico en el recién nacido
Authors: Plata Rueda Ernesto
Published: August 2020

La noción de traumatismo obstétrico con relación al recién nacido, aparecen todas aquellas lesiones externas o internas producidas en este, como consecuencia del trabajo obstétrico o del parto.
Diversos procedimientos aplicables en el tratamiento de la vejiga neurogénica
Authors: Ney Charles , Ramírez Gutiérrez Alfonso
Published: August 2020

Los problemas envueltos en  el tratamiento de la vejiga neurogénica, son bien conocidos para la mayoría de los urólogos y en los últimos años, como resultado de las heridas de la médula, en la segunda guerra mundial. Se ha notado un resurgimiento de interés en este campo.
Observaciones sobre la inducción al trabajo del parto por la administración del Pitocín Endovenoso
Authors: Gómez Palacino Manuel José
Published: August 2020

Las pacientes inducidas para prueba de trabajo, una con antecedentes de miomectomía y primípara; la segunda, también primípara, con diagnóstico elínico de desproporción pevilfetal, el cual se comprobó una vez desencadenas las contracciones.
A propósito de un artículo reciente
Authors: Riviére Marc.
Published: August 2020

La técnica que ha adoptado varía según la edad del embarazo que va a interrumpi­r: dilatación con bujís de Hegar y curetaje para los embarazos muy jóve­nes; histerotomía vaginal para las gestaciones más avanzadas, hasta el 6º mes incluido. Los detalles de la operación los expone minuciosamente el autor; los resultados inmediatos y lejanos de tales.
Comentarios al trabajo del doctor Enrique Darnalt Restrepo
Authors: Bernal Héctor Enrique
Published: August 2020

Terminada la exposición del doctor Darnalt, el presidente lo felicita por su trabajo que es en realidad una recopilación ordenada y muy bien llevada.
Las alteraciones anatomopatológicas del Shock Obstétrico
Authors: Schiavo Carlos D.
Published: August 2020

Estudiar las alteraciones anátomohistologicas que el shock obstétrico provoca en una enferma en estado grávido-puerperal, constituye un jalón sumamente importante en el intento de aclarar su complejo mecanismo fisiopatológico, puesto que con la exacta dilucidación de aquéllas puede llegar a conocerse este último.
Consideraciones sobre 3.000 partos
Authors: Capasso Camilo
Published: August 2020

El que ha estudiado o estudia los diversos trataos de obstetricia, ve en ellos como los distintos autores enseñan, basados en estadísticas de sus respectivos países, la diferencia, la frecuencia de las diferentes presentaciones, el peso y la talla de los fetos a termino, la frecuencia de intervenciones como aplicaciones de fórceps, cesarías, versiones y el porcentaje de las diversas distocias etc.
Algunas consideraciones sobre placentas y sangres del cordón umbilical y materno
Authors: Forero Neira Jesús M.
Published: August 2020

Desempeñando la placenta la función de pulmón del feto durante  su vida intrauterina, pensé que pudiera haber alguna relación entre el tamaño de la placenta entre su superficie de inserción o entre su peso comparado con el del feto y la cantidad de hemoglobina o de glóbulos rojos en el feto.
Misión de nuestra sociedad
Authors: Silva Mojica C. R.
Published: August 2020

La mesa Directiva actual de  la Sociedad Colombiana de obstetricia y Ginecología se encuentra seriamente intencionada en una  labor de orientación científica. El Presidente, doctor Arturo Aparicio, fué bastante enfático desde el momento mismo de tomar posesión de su cargo y dar comienzo a las labores de este nuevo período de la corporación. Puso de presente en forma clara que la  finalidad de  la Sociedad es ante todo científica y secundariamente gremial máxime ante las circunstancias presentes en que obstetras y ginecólogos deben prestar atención especialísima a la organización del ya muy próximo primer Congreso Nacional de Obstetricia y  Ginecología.
Una orientación terapéutica en la eclampsia
Authors: Cubillos R. Luis Guillermo
Published: August 2020

Consigno mi reconocimiento muy sincero al señor Director de la Clínca Primero de Mayo, doctor José Vicente Sánchez Zapata, quien en representación del I. C. S. S. aceptó e hizo posible la realización de esta nueva orientación terapéutica.
Improving the use of ICT through online professional development platform based on metacognitive strategies
Authors: Celen Fatma Kubra , Seferoglu Suleyman Sadi
Published: August 2020

In this study, it is aimed to developing an online professional development practice to support teachers’ use of ICT. The study was conducted as an action research. Within the scope of action research, the data collection/analysis process, the situation and problems have been identified and the action/implementation plan has been developed. Within the scope of the action/implementation plan, the process of structuring the professional development programme and the development of the online learning environment was carried out. The study group consists of teachers with different ICT usage competency levels, professional experiences and branches. The data were collected through different data collection tools, which were personal information form, semi-structured interview forms and valid and reliable scales. As a result of the study, it was determined that the online professional development practice contributed positively to teachers’ use of ICT and the use of meta cognitive learning strategies. In this context, an online professional development model has been proposed that can support the use of ICT in the teaching–learning process in the context of developing ICT knowledge and skills, using meta cognitive learning strategies, and awareness of new technologies.
 
Keywords: Online learning, ICT, professional development, metacognition, technology use.
Basal Plane Bending of Homoepitaxial MPCVD Single-crystal Diamond
Authors: Han Xiaotong , Duan Peng , Peng Yan , Xie Xuejian , Wang Xiwei , Yu Jinying , Hu Xiufei , Wang Dufu , Hu Xiaobo , Xu Xiangang
Published: August 2020

We report herein high-resolution x-ray diffraction measurements of basal plane bending of homoepitaxial single-crystal diamond (SCD). The results reveal that growth parameters such as temperature, growth time and basal plane bending of the substrate affect the basal plane bending of SCD. First, the basal plane bending of SCD depends mainly on the substrate itself. The basal plane bending of SCD becomes more severe with increasing basal plane bending of the substrate and this type of basal plane bending cannot be recovered. The SCD growth experiments show that the basal plane bending increases at high temperature and with increasing growth time. Finally, to understand the mechanism behind basal plane bending, we investigate the substrate-surface temperature distribution as a function of basal plane bending of SCD fabricated by chemical vapour deposition (CVD). This allows us to propose a bending model and understand the origin of basal plane bending. The results indicate that an uneven temperature distribution on the substrate surface is the main cause of the CVD diamond base-plane bending.
Mining Stack Overflow: a Recommender Systems-Based Model
Authors: Harrag Fouzi , Khamliche Mokdad
Published: August 2020

In software development, developers received bug reports that describe the software bug. Developers find the cause of bug through reviewing the code and reproducing the abnormal behavior that can be considered as tedious and time-consuming processes. The developers need an automated system that incorporates large domain knowledge and recommends a solution for those bugs to ease on developers rather than spending more manual efforts to fixing the bugs or waiting on Q&A websites for other users to reply to them. Stack Overflow is a popular question-answer site that is focusing on programming issues, thus we can benefit knowledge available in this rich platform. This paper, presents a survey covering the methods in the field of mining software repositories. We propose an architecture to build a recommender System using the learning to rank approach. Deep learning is used to construct a model that solve the problem of learning to rank using stack overflow data. Text mining techniques were invested to extract, evaluate and recommend the answers that have the best relevance with the solution of this bug report.
Peer-to-Peer Energy Trading and the Sharing Economy: Social, Markets and Regulatory Perspectives
Authors: Schneiders Alexandra , Fell Michael , Nolden Colin
Published: August 2020

Peer-to-peer (P2P) energy trading is a new data-driven business model currently being trialed within the energy sector. Introducing P2P transactions to an essential service such as energy could have far-reaching implications for individuals and the grid. This paper raises considerations and questions from social, economic/markets and regulatory points of view, that should be understood and addressed by societies and policymakers. It does this by considering under what circumstances it is reasonable to conceptualize P2P energy trading as part of the sharing economy, and drawing parallels to the sharing economy experience in other sectors. In order to reap the full societal benefits, while avoiding considerable risks to infrastructure and individuals, a policy approach promoting dialogue and innovation is necessary. We suggest the regulatory sandbox is the most appropriate tool to achieve this and would help avoid the breakdown of trust between policymakers and platform companies observed in other sectors.
Dynamic, Fully Coupled, Electro-mechanical Models of Tidal Turbines
Authors: Ortega Arturo , Tomy Joseph Praful , Shek Jonathan , Paboeuf Stephane , Ingram David
Published: August 2020

Production of electricity using hydro-kinetic tidal turbines has many challenges that must to be overcome to ensure reliable, economic and practical solutions. Energy from flowing water is converted by a system comprising: the turbine rotor blades, a gearbox, an electrical generator, control systems, power electronics, export cables, and a connection to the electricity grid. To date these have often been modelled using simulations of independent systems, lacking bi-directional, real-time, coupling. This approach leads to critical effects being missed. Turbulence in the flow, results in large velocity fluctuations around the blades, causing rapid variation in the shaft torque and generator speed, and consequently in the voltage seen by the power electronics and consequently the export power quality. The resulting poor quality power may be unacceptable to the grid. Conversely, grid frequency and voltage changes can also cause the generator speed to change, resulting in changes to the shaft speed and torque and consequently changes to the lift and drag forces acting on the blades. Clearly, fully integrated, bi-directional, models are needed. Here we present two fully coupled models which use different approaches to model the hydrodynamics of rotor blades. The first model uses Blade Element Momentum Theory (BEMT), resulting in an efficient tool for turbine designers. The second model also uses BEMT combines this with an actuator line model of the blades coupled to an unsteady computational fluid dynamics (CFD) simulation. This simulation, implemented in OpenFOAM, uses an energy balance to compute the shaft speed. Both the BEMT and CFD models are coupled to an Open Modellica model of the electro-mechanical system. Both models have been used to simulate the performance of a 1.2m diameter, scale model, of a three bladed horizontal axis tidal turbine tested in the University of Edinburgh FloWave Ocean Energy Research Facility. The turbulent flow around the blades and the mechanical-electrical variables during the stable period of operation are analysed. Time series and tabulated average values of mechanical thrust, power, torque, and rotational speed as well as electrical variables of generator power, electromagnetic torque, voltage and current are presented for the coupled system simulation. The relationship between the mechanical and electrical variables and the results from both tidal turbine approaches are discussed. Our comparison shows that while the BEMT model provides an effective design tool (leading to slightly more conservative designs), the CFD/BEMT simulations provide more accurate predictions of the blade loads which can be especially important in assessing fatigue on the blades (though at an increased computational cost).