bluuebunny/crossref_metadata_2025 huggingface dataset:
Moderation effect of community health on the relationship between racial/ethnic residential segregation and HIV viral suppression in South Carolina: A county-level longitudinal study from 2013 to 2018
Authors: Shi Fanghui , Zhang Jiajia , Yang Xueying , Sun Xiaowen , Li Zhenlong , Zeng Chengbo , Ning Huan , Weissman Sharon , Olatosi Bankole , Li Xiaoming
Published: January 2023

Background

Viral suppression is the ultimate goal of the HIV treatment cascade and a primary endpoint of antiretroviral therapy. Empirical evidence found racial/ethnic disparities in viral suppression among people living with HIV (PWH), but the evidence of the relationship between racial/ethnic residential segregation and place-based viral suppression is scarce. Further exploring potential structural moderators in this relationship has substantial implications for healthcare policymaking and resource allocation. The current study aimed to investigate the spatial-temporal disparities in the HIV viral suppression rate across 46 counties in South Carolina from 2013 to 2018. We also examined the impact of racial/ethnic residential segregation and the moderation effect of community health, one measurement of community engagement and volunteerism.

Methods

The proportion of PWH who achieved viral suppression for each county and calendar year was calculated using de-identified electronic medical records. The isolation index was calculated and used to measure racial/ethnic residential segregation. The community health index and other county-level factors were directly extracted from multiple publicly available datasets. We used geospatial mapping to explore the spatial-temporal variations of HIV viral suppression rates. Hierarchical quasi-binominal regression models were used to examine the impacts of racial/ethnic residential segregation on county-level viral suppression rate by the extent of community health.

Results

From 2013 to 2018, the average viral suppression rate across 46 counties in SC increased from 64.3% to 65.4%. Regression results revealed that counties with high racial/ethnic residential segregation were more likely to have a low viral suppression rate (β = −0.56, 95% CI: −0.75 to −0.37). In counties with high levels of community health, the impact of racial/ethnic residential segregation on viral suppression rate decreased as compared with those with low levels of community health (β = 5.50, 95% CI: 0.95–10.05).

Conclusions

Racial/ethnic residential segregation acts as a structural barrier to placed-based viral suppression rates and compromises the goal of the HIV treatment cascade. Concentrated and sustained county-level interventions aiming to improve community health can be practical approaches to promote health equity in HIV treatment and care.
Balance ability and all-cause death in middle-aged and older adults: A prospective cohort study
Authors: Xie Kaihong , Han Xiao , Hu Xuanhan
Published: January 2023

Objective

The present study aimed to explore the relationship between balance ability and all-cause death in middle-aged and elderly people and to provide a basis for formulating a balanced training plan for middle-aged and older people in China.

Methods

Based on data from the China Health and Retirement Longitudinal Study (CHARLS) carried out in the years 2011, 2013, 2015, and 2018, 18,888 participants aged 45 years and above were included. Cox proportional hazard models were designed to evaluate the effect of balance ability on death events.

Results

The present study found that there was an association between balance ability and death among middle-aged and older people. Multivariate Cox proportional hazard regression model analysis showed that the risk of death decreased by 10% (HR = 0.90,95% CI: 0.85–0.95) for every second increase in balance ability. With balance ability <10 s as the reference group, the adjusted HRs were 0.61 (0.44–0.85) among middle-aged and elderly people. The death density of balance ability of <10 s was 73.87 per thousand person-years higher than that of ≥10 s. There was no interaction between balance ability and chronic disease, overweight, and obesity (P > 0.05).

Conclusion

The risk of all-cause death in middle-aged and older people increased with the decrease in balance ability and showed no statistical significance between chronic disease, overweight, and obesity, as corroborated by the present study.
Persistence of IgG COVID-19 antibodies: A longitudinal analysis
Authors: Carvalho Álvaro , Henriques Ana Rita , Queirós Paula , Rodrigues Joana , Mendonça Nuno , Rodrigues Ana Maria , Canhão Helena , de Sousa Germano , Antunes Francisco , Guimarães Miguel
Published: January 2023

Background and aim

The kinetics of antibody production in response to coronavirus disease 2019 (COVID-19) infection is not well-defined yet. This study aimed to evaluate the antibody responses to SARS-CoV-2 and its dynamics during 9-months in a cohort of patients infected during the first phase of the pandemic. As a secondary aim, it was intended to evaluate the factors associated with different concentrations of IgG antibodies.

Methods

A prospective cohort study was conducted from June 2020 to January 2021. This study recruited a convenience sample of adult individuals who where recently diagnosed with COVID-19 and were living in mainland Portugal. A total of 1,695 blood samples were collected from 585 recovered COVID-19 patients up to 9 months after SARS-CoV-2 acute infection. A blood sample was collected at baseline and three, 6 and 9 months after SARS-CoV-2 acute infection to assess the concentration of IgG antibody against SARS-CoV-2.

Results

The positivity rate of IgG reached 77.7% in the first 3 months after symptom onset. The IgG persists at all subsequent follow-up time-points, which was 87.7 and 89.2% in the 6th and 9th months after symptom onset, respectively. Three distinct kinetics of antibody response were found within the 9 months after infection. Kinetic 1 (K1) was characterized by a constant low IgG antibody concentration kinetic (group size: 65.2%); kinetic 2 (K2), composed by constant moderate IgG kinetic (group size: 27.5%) and kinetic 3 (K3) characterized by higher IgG kinetic (group size: 7.3%). People with ≥56 years old (OR: 3.33; CI 95%: [1.64; 6.67]; p-value: 0.001) and symptomatic COVID-19 (OR: 2.08; CI 95%: [1.08; 4.00]; p-value: 0.031) had higher odds of a “Moderate IgG kinetic.” No significant association were found regarding the “Higher IgG kinetic.”

Conclusion

Our results demonstrate a lasting anti-spike (anti-S) IgG antibody response at least 9 months after infection in the majority of patients with COVID-19. Younger participants with asymptomatic disease have lower IgG antibody positivity and possibly more susceptible to reinfection. This information contributes to expanding knowledge of SARS-CoV-2 immune response and has direct implications in the adoption of preventive strategies and public health policies.
COVID-19 epidemic and public health interventions in Shanghai, China: Statistical analysis of transmission, correlation and conversion
Authors: Yi Dali , Chen Xicheng , Wang Haojia , Song Qiuyue , Zhang Ling , Li Pengpeng , Ye Wei , Chen Jia , Li Fang , Yi Dong , Wu Yazhou
Published: January 2023

Background

The Shanghai COVID-19 epidemic is an important example of a local outbreak and of the implementation of normalized prevention and disease control strategies. The precise impact of public health interventions on epidemic prevention and control is unknown.

Methods

We collected information on COVID-19 patients reported in Shanghai, China, from January 30 to May 31, 2022. These newly added cases were classified as local confirmed cases, local asymptomatic infections, imported confirmed cases and imported asymptomatic infections. We used polynomial fitting correlation analysis and illustrated the time lag plot in the correlation analysis of local and imported cases. Analyzing the conversion of asymptomatic infections to confirmed cases, we proposed a new measure of the conversion rate (Cr). In the evolution of epidemic transmission and the analysis of intervention effects, we calculated the effective reproduction number (Rt). Additionally, we used simulated predictions of public health interventions in transmission, correlation, and conversion analyses.

Results

(1) The overall level of Rt in the first three stages was higher than the epidemic threshold. After the implementation of public health intervention measures in the third stage, Rt decreased rapidly, and the overall Rt level in the last three stages was lower than the epidemic threshold. The longer the public health interventions were delayed, the more cases that were expected and the later the epidemic was expected to end. (2) In the correlation analysis, the outbreak in Shanghai was characterized by double peaks. (3) In the conversion analysis, when the incubation period was short (3 or 7 days), the conversion rate fluctuated smoothly and did not reflect the effect of the intervention. When the incubation period was extended (10 and 14 days), the conversion rate fluctuated in each period, being higher in the first five stages and lower in the sixth stage.

Conclusion

Effective public health interventions helped slow the spread of COVID-19 in Shanghai, shorten the outbreak duration, and protect the healthcare system from stress. Our research can serve as a positive guideline for addressing infectious disease prevention and control in China and other countries and regions.
COVID-19 as a risk factor for long-term mortality in patients managed by the emergency medical system: A prospective, multicenter, ambulance-based cohort study
Authors: Martín-Conty José L. , Polonio-López Begoña , Sanz-García Ancor , del Pozo Vegas Carlos , Mordillo-Mateos Laura , Bernal-Jiménez Juan José , Conty-Serrano Rosa , Castro Villamor Miguel A. , López-Izquierdo Raúl , Martín-Rodríguez Francisco
Published: January 2023

Introduction

COVID-19 has initially been studied in terms of an acute-phase disease, although recently more attention has been given to the long-term consequences. In this study, we examined COVID-19 as an independent risk factor for long-term mortality in patients with acute illness treated by EMS (emergency medical services) who have previously had the disease against those who have not had the disease.

Methods

A prospective, multicenter, ambulance-based, ongoing study was performed with adult patients with acute disease managed by EMS and transferred with high priority to the emergency department (ED) as study subjects. The study involved six advanced life support units, 38 basic life support units, and five emergency departments from Spain. Sociodemographic inputs, baseline vital signs, pre-hospital blood tests, and comorbidities, including COVID-19, were collected. The main outcome was long-term mortality, which was classified into 1-year all-cause mortality and 1-year in- and out-of-hospital mortality. To compare both the patients with COVID-19 vs. patients without COVID-19 and to compare survival vs non-survival, two main statistical analyses were performed, namely, a longitudinal analysis (Cox regression) and a logistic regression analysis.

Results

Between 12 March 2020 and 30 September 2021, a total of 3,107 patients were included in the study, with 2,594 patients without COVID-19 and 513 patients previously suffering from COVID-19. The mortality rate was higher in patients with COVID-19 than in patients without COVID-19 (31.8 vs. 17.9%). A logistic regression showed that patients previously diagnosed with COVID-19 presented higher rates of nursing home residency, a higher number of breaths per minute, and suffering from connective disease, dementia, and congestive heart failure. The longitudinal analysis showed that COVID-19 was a risk factor for mortality [hazard ratio 1.33 (1.10–1.61); p < 0.001].

Conclusion

The COVID-19 group presented an almost double mortality rate compared with the non-COVID-19 group. The final model adjusted for confusion factors suggested that COVID-19 was a risk factor for long-term mortality.
The research progress of Chikungunya fever
Authors: Cai Li , Hu Xinyi , Liu Shuang , Wang Lei , Lu Hao , Tu Hua , Huang Xibao , Tong Yeqing
Published: January 2023

Chikungunya fever, an acute infectious disease caused by Chikungunya virus (CHIKV), is transmitted by Aedes aegypti mosquitoes, with fever, rash, and joint pain as the main features. 1952, the first outbreak of Chikungunya fever was in Tanzania, Africa, and the virus was isolated in 1953. The epidemic has expanded from Africa to South Asia, the Indian Ocean islands and the Americas, and is now present in more than 100 countries and territories worldwide, causing approximately 1 million infections worldwide each year. In addition, fatal cases have been reported, making CHIKV a relevant public health disease. The evolution of the virus, globalization, and climate change may have contributed to the spread of CHIKV. 2005–2006 saw the most severe outbreak on Reunion Island, affecting nearly 35% of the population. Since 2005, cases of Chikungunya fever have spread mainly in tropical and subtropical regions, eventually reaching the Americas through the Caribbean island. Today, CHIKV is widely spread worldwide and is a global public health problem. In addition, the lack of a preventive vaccine and approved antiviral treatment makes CHIKV a major global health threat. In this review, we discuss the current knowledge on the pathogenesis of CHIKV, focusing on the atypical disease manifestations. We also provide an updated review of the current development of CHIKV vaccines. Overall, these aspects represent some of the most recent advances in our understanding of CHIKV pathogenesis and also provide important insights into the current development of CHIKV and potential CHIKV vaccines for current development and clinical trials.
Health education via “empowerment” digital marketing of consumer products and services: Promoting therapeutic benefits of self-care for depression and chronic pain
Authors: Huntsman Jade L. , Bulaj Grzegorz
Published: January 2023

Increasing health care costs and high economic burden exemplify the impact of chronic diseases on public health. Multifaceted approaches to treating chronic diseases include pharmaceutical drugs, digital therapeutics, and lifestyle medicine. Chronic diseases are largely preventable, and health promotion yields positive outcomes. However, despite positive return on investment (ROI) and cost-to-benefit ratio (CBR) for health promotion (median ROI 2.2, median CBR 14.4), commercial marketing of healthy lifestyles and self-care is limited. The objective of this perspective article is to discuss how digital marketing of consumer goods and services that support therapeutic self-care can also bridge public health and for-profit interests. We describe how “empowerment” marketing campaigns can provide evidence-based associations between products/services and self-care benefits for people living with chronic pain and depression. Such a “health education as marketing” strategy is illustrated by educational ads describing how contact with nature, music, and yoga can improve chronic pain and reduce depressive symptoms. Creating associations between health-related benefits of these activities with products (outdoor and yoga apparel, audio equipment) and services (music streaming services, music mobile apps, eco-tourism, yoga studios) that support them expand their value proposition, thus incentivizing profit-driven companies to engage in public health campaigns. Long-term success of companies that incorporate evidence-based health education as marketing and branding strategies will depend on following ethical considerations and advertising guidelines defined by consumer protection regulatory agencies, such as the Federal Trade Commission (FTC). In conclusion, integration of health education about self-care and commercial marketing can support health care outcomes and disease prevention.
The impact of trust in government on pandemic management on the compliance with voluntary COVID-19 vaccination policy among adolescents after social unrest in Hong Kong
Authors: Chung Gary Ka-Ki , Chan Yat-Hang , Chan Siu-Ming , Chen Ji-Kang , Wong Hung , Chung Roger Yat-Nork
Published: January 2023

Background

The launch of COVID-19 vaccines among students provides an opportunity to re-open schools safely. Nonetheless, under the voluntary vaccination policy, the lack of trust in government since the unprecedented massive social unrest in Hong Kong may hinder the vaccination progress. This study aims to assess the impact of trust in government regarding pandemic management on the willingness, uptake, and intention of COVID-19 vaccination among students in Hong Kong.

Methods

Based on maximum variation sampling of 12 secondary schools of diverse socioeconomic background, 1,020 students aged 14–16 years completed an online survey between September and October 2021.

Results

59.2% of the sample received at least one dose of the COVID-19 vaccine, 25.2% showed willingness of vaccination, 44.7% of the unvaccinated intended to receive the vaccine, whereas 13.4% were trustful to the government regarding pandemic management. Results from multivariable logistic regressions showed independent associations of trust with greater vaccination uptake [aOR = 1.63 (95% CI = 1.06–2.52), compared to distrust], willingness [aOR = 12.40 (7.72–19.93)], and intention [aOR = 4.49 (2.06–9.75)]. However, the impact of trust on vaccine uptake reversed [aOR = 0.53 (0.32–0.87)] after additional adjustment for the willingness of vaccination.

Conclusion

Students with higher trust in government regarding pandemic management tended to have greater vaccination willingness and hence uptake; nonetheless, given the same level of willingness, distrust might have facilitated a faster adoption of vaccination as a self-initiated protective behavior. As the level of trust is generally low among secondary school students in Hong Kong, rebuilding trust during adolescence is of importance for better preparedness of the next pandemic.
Strengthening financial management systems at primary health care: Performance assessment of the Facility Financial Accounting and Reporting System (FFARS) in Tanzania
Authors: Ruhago George M. , Ngalesoni Frida N. , Kapologwe Ntuli A. , Kengia James T. , Ngocho James , Kabusi Stephen M. , Kalolo Albino , Kitali Erick J. , Rwamiago Elisa , Mtei Gemini
Published: January 2023

Background

Universal coverage remains a challenging pursuit around the world, even among the highest-income countries. Strengthening financial management capacity is essential towards attaining the three universal health coverage (UHC) goals, namely, expanded coverage, quality service, and financial protection. In this regard, Tanzania introduced the Facility Financial Accounting and Reporting System (FFARS) in line with the introduction of the Direct Health Facility Financing (DHFF) initiative in primary health care (PHC) in 2017–2018. We aim to assess the functionality of the FFARS in management, accounting, and reporting funds received and disbursed in the stride forward strengthening public financial management in PHC facilities towards UHC.

Methods

The study applied implementation research using a concurrent convergent mixed-methods design to assess sources of revenue, expenditure priorities, and changes of revenues and to explore the usability and benefits of FFARS in improving facility finance and reporting systems in more than 5,000 PHC facilities in Tanzania. Quantitative methods assessed the changes in revenues and expenditure between the financial years (FYs) 2017–2018 and 2018–2019, while the qualitative part explored the usability and the benefits FFARS offers in improving facility finances and reporting systems. Data analysis involved a thematic and descriptive analysis for qualitative and quantitative data, respectively.

Results

Of the 5,473 PHC facilities, 88% were in rural areas; however, the annual average revenue was higher in urban facilities in FYs 2017–2018 and 2018–2019. Overall, district hospitals showed an increase whereas health centers reported a decline of more than 40% in revenue. The user fee was the predominant source of revenue, particularly in urban facilities, while revenue from health insurance was not among the top three highest sources of revenue. Expenditure priorities leaned more towards drugs and supplies (25%) followed by allowances and training (21%); these did not differ by facility geographies. In health centers, expenditure on facility infrastructure was predominant. Key Informant Interviews revealed an overall satisfaction and positive experiences related to the system.

Conclusion

The implementation of FFARS in Tanzania demonstrated its high potential in improving facility financial management, including its ability to track revenue and expenditure at PHC facilities. Staffing shortages, ICT infrastructure, and limited opportunities for capacity building could be the limiting factors to reaching the potential of the implementation of FFARS and the attainment of its full impact on Tanzania's pursuit for UHC.
Gender differences in smallholders' socioeconomic networks and acquisition of seed of improved wheat varieties in Ethiopia
Authors: Jaleta Moti , Euler Michael , Gartaula Hom , Krishna Vijesh
Published: January 2023

Enhancing farmers' access to improved seeds is essential to increase productivity and ensure food security in the Global South. However, for many socially marginalized groups, seed access is constrained by the weak institutions governing the input supply chains and the dissemination of information. Using cross-sectional survey data collected from 1,088 farming households in three major wheat-growing regional states of Ethiopia in 2021, this paper assesses empirically how participation in different socioeconomic institutions by men and women farmers shapes their access to and acquisition of seed of improved wheat varieties. The results show that the seed market in the study area is largely informal, where the recycling of wheat seeds from the previous season is a common practice among both male- and female-headed households. However, a significant difference exists between male- and female-headed households regarding patterns of varietal use, with male farmers growing newer wheat varieties more frequently. Men are also more active than women in local social and economic institutions, and their participation is positively associated with the adoption of new wheat varieties. Thus, strengthening the local social and economic institutions and supporting equitable participation of both male- and female-headed households in these institutions could facilitate the diffusion of quality seeds of improved and recently released wheat varieties in countries where the informal seed system plays a major role in seed acquisition.
Local autologous platelet rich plasma injection combined with platelet rich fibrin filling as the main treatment for refractory wounds: A case series
Authors: Liu Xiang , Li Xiangjun , Wei Wei , Zhang Xiang , Fang Zheng , Chen Zixiu , Chen Pingxiang , Li Haihong
Published: January 2023

Refractory wounds are a major global health problem that not only affects the quality of life, but also causes significant physical, psychological and economic burdens. How to promote wound healing has become the main goal of clinicians. To evaluate the safety and efficacy of local autologous platelet rich plasma (PRP) injection combined with platelet rich fibrin (PRF) filling as the main treatment for refractory wounds. In the study, autologous PRP and PRF were prepared from whole blood. Twelve patients, each having a refractory wound, were included. The wounds were debrided first to remove necrotic and infected tissues, and then were given once or twice local PRP injection combined with PRF filling treatment. The total healing time (the time from admission to wound healing) and the healing time after PRP/PRF combined treatment (the time from PRP treatment to wound healing), as well as the adverse events were recorded. The results showed that the wound duration before the combination treatment was 10.48 ± 3.66 weeks, and the mean area/volume (for sinus or fistula) of the wounds was 8.23 ± 2.67 cm2/9.54 ± 2.13 cm3 (for sinus or fistula). All wounds healed after once or twice PRP/PRF combined treatment. The total healing time was 26.91 ± 8.01 days, and the healing time after the combined treatment was 16.36 ± 7.47 days. No adverse events were reported during the treatment and follow-up period. Our case series demonstrate the safety and synergistic effectiveness of local autologous PRP injection combined with PRF filling as the main treatment for refractory wounds. Platelet concentrates is not only an adjuvant treatment for chronic wounds, but a potential substitute for chronic wounds, especially in sinuses and fistulas.
Reconstruction of a nail bed with double-layer artificial dermis for a pincer nail: A case report and literature review
Authors: Deng Weicong , Zhou Zelin , Leng Bo , Zeng Xinming , Shen Zi , Hong Yongchang
Published: January 2023

Background

A pincer nail (PN) is a type of nail deformity. Although it is a minor ailment, it can cause intractable pain, affecting daily work and life. Currently, there is no standard invention for PN. The main purpose of treatment is to correct the curvature of the nail, so we apply double-layer artificial dermis (DLAD), a novel treatment, for PN according to this aim.

Case presentation

A 40-year-old man suffering from PN was treated with DLAD. After 1 year of follow-up, the patient's great toenail plate of the right foot was completely grown out. His pain was relieved, and the curvature of the toenail was corrected.

Conclusion

The innovative method of using DLAD to fill the ingrown nail bed not only solves the problem of recurrent pincer nail deformity but also restores the original appearance of the toenail. It suggested that this simple procedure can be widely applied in clinical practice.
Pre-operative predictive factors of residual varus on the mechanical axis after Oxford unicompartmental knee arthroplasty
Authors: Ji Songjie , Huang Ye , Zhou Yixin , Wang Chao , Wang Xiaokai , Ma Chaoyi , Jiang Xu
Published: January 2023

Background

Residual varus after Oxford unicompartmental knee arthroplasty (UKA) happens frequently. This study aims to evaluate the pre-operative contributing factors of residual varus.

Methods

A total of 1,002 knees (880 patients, 201 patients were male, and 679 were female) underwent Oxford UKA in the Orthopedic Surgery Department of the Beijing Jishuitan Hospital from March 2018 to April 2021. The mean age of the patient was 64.7 ± 7.7 years. To assess residual varus, the full-length lower extremity is placed upright for EOS imaging, with the knee fully extended. The angle of post-operative residual varus was measured as described by Noyes et al. Of the knees studied, they were either categorized into an under-corrected group (post-operative Noyes angle >5°) or a corrected group (post-operative Noyes angle ≤5°). Age, gender, body mass index (BMI), range of motion (ROM), Clinical American Knee Society Score (Clinical AKSS), and Function American Knee Society Score (Function AKSS) were compared. The following additional parameters were measured: pre-operative Noyes angle, lateral distal femoral angle (LDFA), medial proximal tibial angle (MPTA), the posterior slope of the proximal tibia angle (PPTA), joint line converge angle (JLCA), and fixed flexion deformity (FFD).

Results

There was no statistically significant difference between the two groups in regards to gender (p = 0.428), surgical leg (p = 0.937), age (p = 0.851), BMI (p = 0.064), pre-operative Clinical AKSS (p = 0.206) and Function AKSS (p = 0.100). However, pre-operative ROM statistically differed between the two groups (p < 0.001). The contributing factors of post-operative residual varus were determined to be the following parameters: pre-operative MPTA (p < 0.001, OR = 4.522, 95% CI: 2.927–6.984), pre-operative Noyes (p < 0.001, OR = 3.262, 95% CI: 1.802–5.907) and pre-operative FFD (p = 0.007, OR = 1.862, 95% CI: 1.182–2.934). The effects of pre-operative LDFA (p = 0.146), JLCA (p = 0.942), and pre-operative PPTA (p = 0.899) on the post-operative mechanical axis did not show statistical significance.

Conclusions

Patients with severe pre-operative varus, particularly varus deformity mainly from the tibial side or pre-operative FFD, are more prone to get extremity mechanical axis residual varus after UKA with Oxford.
Trachea repair using an autologous pericardial patch combined with a 3D carbon fiber stent: A case report
Authors: Wang Bin , Zhang Zhe , Guo Yuanwei , Yu Fenglei
Published: January 2023

This study is the first to use an autologous pericardial patch combined with a 3D carbon fiber stent for the plastic repair of a large trachea defect. Radical surgery is the optimal therapy for primary malignant tracheal tumors. Tracheoplasty or repair is required to guarantee trachea integrity and normal ventilation function after tracheal tumor resection. Here, we present a case of plastic repair of the trachea using an autologous pericardial patch and a 3D custom-made carbon fiber stent. A 4 cm trachea defect was successfully repaired after resecting a malignant schwannoma. The postoperative ventilatory function was normal without obvious symptoms of discomfort. Fiberoptic bronchoscopy showed a smooth mucosal surface of the endotracheal wall and patency of the airway. CT scans performed 3 years after surgery showed no recurrence. Therefore, we can conclude that a 3D carbon fiber stent is feasible for abolishing patch floating and preventing tracheal stenosis.
Comparison of C2 dome-like laminectomy with C2 partial laminectomy for upper cervical ossification of the posterior longitudinal ligament
Authors: Miao Dazhuang , Gao Xianda , Zhen Zihao , Yang Dalong , Wang Hui , Ding Wenyuan
Published: January 2023

Objective

To compare surgical outcomes of C2 dome-like laminectomy with C2 partial laminectomy in patients with ossification of the posterior longitudinal ligament (OPLL) up to the C2 level and above.

Methods

32 patients underwent surgical treatment for OPLL up to C2 and were divided into: C2 dome-like laminectomy group (C2-DOM group, n = 16) and C2 partial laminectomy group (C2-PL group, n = 16). The cervical curvature (CCI), dura width at C2/3, Japanese orthopedic association (JOA) score, recovery rate (RR), neck disability index (NDI) score, and visual analogue scale (VAS) score were evaluated and compared preoperatively and postoperatively at 1 month, 3 months, 6 months, 1 year, and annually thereafter.

Results

The JOA score and NDI significantly improved at the final follow-up in both groups with no significant intergroup differences. There were no significant differences in preoperative dura width at C2/3 and VAS between the two groups. At the final follow-up, dura width at C2/3 in the C2-PL group was significantly larger than the C2-DOM group, while the VAS of C2-DOM group was significantly lower than C2-PL group. The CCI in both groups decreased compared with before surgery, and there was no significant difference in CCI between the two groups.

Conclusion

C2-DOM is less demolitive and reduces postoperative neck pain, while C2-PL can achieve more adequate decompression without increasing the risk of postoperative cervical kyphosis.
Continuous cement leakage along the posterior longitudinal ligament of the intraspinal epidural during a percutaneous vesselplasty: A case report and literature review
Authors: An Ning , Guo Sijia , Lin Jisheng , Zhuang Haoxiang , Meng Hai , Su Nan , Fei Qi
Published: January 2023

Objective

This study aims to report one case of intraspinal epidural cement leakage caused by a novel percutaneous vesselplasty.

Methods

A clinical case report from the Orthopedic center of our hospital and a literature review. A 63-year-old woman with an L2 osteoporotic compression fracture underwent novel kyphoplasty, percutaneous vesselplasty. This rare complication was evaluated through a literature search, and its special types are classified in more detail.

Results

The patient was hospitalized with low back pain two weeks after a fall. After auxiliary examination, a new type of percutaneous vesselplasty was performed. After the intraoperative injection of bone cement, bone cement leakage extended along the posterior longitudinal ligament and epidural space. There were no special compression symptoms of the spinal cord, and the prognosis of conservative treatment was good.

Conclusion

Although percutaneous vesselplasty is relatively safe and frequent, intraspinal leakage may occur, so sufficient preoperative evaluation, intraoperative continuous fluoroscopic monitoring, and timely evaluation of postoperative images are extremely necessary.
Indocyanine green near-infrared imaging-guided lymph node dissection during oesophageal cancer surgery: A single-centre experience
Authors: Chen Saihua , Tian Xiaofeng , Ju Guanjun , Shi Minxin , Chen Yibiao , Wang Qing , Dai Wencheng , Li Tinghua , Pan Jing , Fan Yihui
Published: January 2023

Objective

This study aimed to investigate the feasibility of using indocyanine green (ICG) near-infrared (NIR) imaging during lymphadenectomy for oesophageal cancer.

Methods

Eighty-seven patients with primary oesophageal cancer were enrolled in this study. All the enrolled patients received an endoscopic injection of ICG between 40 min and 23 h before surgery. Nodal dissection during surgery was performed under fluorescence imaging visualisation, with the NIR signal shown in purple. ICG+ or ICG− nodes were recorded station by station and were microscopically evaluated.

Results

Endoscopic peritumoral ICG injection was successfully performed in all patients. Major post-surgery complications included wound infection, pleural effusion, dysphonia, pneumonia and anastomotic fistula. No patients experienced ICG-related adverse events. A total of 2,584 lymph nodes were removed, and the mean number of lymph nodes for each patient was 29.70 ± 9.24. Most of the removed nodes (97.83%) were ICG+, and 3.32% of the ICG+ nodes were metastatic. No metastatic nodes were ICG− or belonged to an ICG− lymph node station. The time from ICG injection to surgery did not affect the number of harvested lymph nodes.

Conclusions

The use of ICG-NIR imaging during oesophageal cancer surgery can enhance the visualisation of lymph nodes during surgery. It is a feasible, safe and helpful technique for lymphadenectomy.
Emergence of human-porcine reassortment G9P[19] porcine rotavirus A strain in Guangdong Province, China
Authors: Luo Shicheng , Chen Xiuqiao , Yan Guangzhi , Chen Shengnan , Pan Jinghua , Zeng Mengyi , Han Hui , Guo Yajing , Zhang Haoquan , Li Jiaming , Mo Meilian , Liu Mingjie , Huang Liangzong
Published: January 2023

Group A rotaviruses of the family Reoviridae is one of the important intestinal pathogens causing diarrhea in piglets and humans. A human-porcine reassortment rotavirus, GDJM1, was identified from outbreak of diarrhea in suckling piglets and it associated with 60.00% (324/540) morbidity and 20.99% (68/324) mortality in Guangdong Province of China in 2022. Thus, to further characterize the evolutionary diversity of GDJM1, all gene segments were analyzed. The genome constellation was G9-P[19]-I5-R1-C1-M1-A8-N1-T1-E1-H1. Nucleotide sequence identity and phylogenetic analyses showed that the VP6, VP7, NSP4 and NSP5 genes of GDJM1 were the most closely related to the respective genes of porcine strains, with the highest homology ranging from 95.65–98.55% identity. The remaining seven genes (VP1-VP4, NSP1-NSP3) were the most closely related to human strains, with the highest homology ranging from 91.83–96.69% similarity. Therefore, it is likely that GDJM1 emerged as the result of genetic reassortment between porcine and human rotaviruses. To our knowledge, this is the first report that a human-porcine reassortment G9P[19] RVA strain has been identified in mainland China, which providing important insights into evolutionary characterization of G9P[19] RVA strain, and reveals that the strain has a potential risk of cross-species transmission.
Apreciaciones del trabajo a distancia en la asignatura de sistemas operativos en Educación Superior
Authors: Reyes-Flores Itzel Alessandra , Soto-Ortiz José Luis
Published: January 2023

A partir del confinamiento derivado por el COVID-19 los procesos de formación de las escuelas, migraron de la modalidad presencial al trabajo a distancia lo que propicio que los estudiantes se adaptaran un nuevo ambiente de aprendizaje aunado a las implicaciones de tipo tecnológicas para continuar con su aprendizaje. Por lo anterior, impera la necesidad de indagar acerca de la adaptación desde las vertientes pedagógica y tecnológica. En este sentido, el objetivo de este artículo fue analizar las apreciaciones de estudiantes de licenciatura acerca del trabajo a distancia. El método fue de tipo mixto, para ello, se aplicó un cuestionario de 20 ítems con escala de Likert de cinco niveles con un alfa de Cronbach de 0,88; por la parte cualitativa se realizó una entrevista semi estructurada. De acuerdo con los resultados obtenidos, los estudiantes indican que el trabajo a distancia fue adecuado a pesar de las limitantes en cuanto a hardware y conexión de Internet. Por su parte, las didácticas aplicadas en línea resultaron favorables para los estudiantes en el desarrollo del curso. En otro tenor, en voz de los participantes señalan que para la realización de las prácticas es necesario el trabajo presencial en los laboratorios de la facultad.
El liderazgo en educación: una nueva visión de la realidad desde el humanismo
Authors: Amazo-Velásco Freddy Miller , Suárez-Molina Verónica Johana
Published: January 2023

En esta investigación se tuvo como objetivo analizar y reflexionar acerca del liderazgo en el contexto educativo. De esta forma, para el análisis se abordó la implementación de un enfoque cualitativo y un diseño hermenéutico que permitió a partir del reconocimiento y reflexión de los aportes teóricos de diferentes autores, hacer una aproximación teórica frente a la definición del líder educativo en un contexto cambiante y permeado por las trasformaciones culturales debido a los cambios en las dinámicas sociales y los estilos de vida de las personas. Así entonces, se presenta en este artículo una nueva visión de la realidad, que plantea ampliar el horizonte y las líneas de acción del líder docente transformador, que busca analizar diferentes paradigmas no solo en la ciencia, sino también, en el contexto social. Para el análisis se consideró igualmente los aportes realizados por Viktor Frankl, quien reafirma la presencia de una existencia espiritual en el ser humano, la cual, le ayuda a evolucionar el sentido de la responsabilidad, para encontrar respuestas a los diferentes interrogantes que surgen en el líder docente transformador, el cual, debe poseer unas habilidades que le permitan transformarse y trascender, para propender y constituir valores tales como la convivencia, la participación, el respeto y el compromiso, para sí, para sus estudiantes y demás actores educativos. Finalmente, el líder debe tener la capacidad de planear, gestionar, liderar y evaluar el proceso educativo en los diferentes momentos y circunstancias.
Calidad de servicio percibido y satisfacción del cliente en Caja Municipal de Sullana
Authors: Güere-Carbajal Carolina Vanessa , Yangali-Vicente Judith Soledad
Published: January 2023

El trabajo de investigación tuvo como finalidad analizar la calidad de servicio percibido y satisfacción del cliente en la agencia Lima Centro de Caja Municipal de Sullana 2022, con el objetivo de establecer la relación entre ellos, de allí, nace lo fundamental que es cuando una entidad del sistema financiero o de otro sector brinda un servicio con calidad con el fin de trascender en forma inmediata en satisfacción del cliente.  La metodología empleada fue de enfoque cuantitativo, tipo básica, diseño o forma no experimental, nivel descriptivo correlacional y corte transversal. La técnica empleada en la recopilación de datos fue la encuesta y se efectuó a través del cuestionario medición de calidad de servicio percibido y la satisfacción del cliente, servqual adaptado para la agencia Lima Centro de la Caja Municipal de Sullana durante el año 2022, se aplicó a 120 clientes por conveniencia. Se concluyó, que sí existe relación buena y positiva (coeficiente de correlación de Spearman r= 0.738) entre calidad de servicio percibido y satisfacción del cliente. Finalmente, con el resultado obtenido de esta investigación se concluyó que la organización podrá tomar decisiones que mejoren el servicio ofrecido mediante la percepción de estos y lograr superar expectativas del cliente, y con ello, satisfacción del cliente generando valor para la organización.
Compromiso organizacional, satisfacción laboral, y su repercusión en el desempeño del personal
Authors: Mamani-Guzmán Carlos , Palacios-Sarmiento Tania Yolanda , Priori-Flores María Belén , Tellez-Pérez Anisleydi
Published: January 2023

El objetivo del presente artículo fue determinar el impacto del compromiso organizacional (CO) y satisfacción laboral (SL) en el desempeño laboral (DL) de los trabajadores, a través de la revisión bibliográfica, analizando, comprendiendo e interpretando la información obtenida de distintos artículos de investigación, realizadas en diversos sectores laborales, ocupacionales y profesionales. El estudio se alineó al paradigma interpretativo-hermenéutico, donde se describió, analizó, comprendió e interpretó las interrelaciones de los constructos (CO, SL y DL). La investigación tiende al enfoque mixto (cuantitativo y cualitativo), pues, se realizó la descripción, comprensión e interpretación de la revisión bibliográfica sobre las variables en estudio, mediante el uso de la bibliometría. Respecto a la metodología, se utilizó el método de la investigación documental. Para la búsqueda y selección de la literatura científica se utilizó el Scopus como gestor bibliográfico y la bibliometría para el estudio de las publicaciones científicas y cuya unidad de análisis es el artículo científico. Los resultados, basados en una muestra de 92 artículos, durante los últimos 19 años, que la cantidad de estudios divulgados y de citas se ha incrementado de manera progresiva. Adicionalmente, los resultados revelan el impacto positivo de las variables CO y SL sobre el DL, del mismo modo, la mediación de los componentes del compromiso y satisfacción de los empleados para la mejora continua del desempeño de estos en el trabajo; esto implica logro de reputación positiva, prestigio e imagen organizacional o empresarial, en síntesis, el comportamiento organizacional con desarrollo sostenible.
Gestión del conocimiento y gestión de cambio: Estudio Bibliométrico
Authors: García-Ramos Taryns Elizabeth , López-Brunett Ana Luisa , Wright-Garzón María Rosa , Varas-Espinoza Nury
Published: January 2023

Este trabajo tiene como objetivo hacer un análisis bibliométrico de las variables: gestión del cambio (CM) y gestión del conocimiento (KM), además, de determinar la tendencia o evolución de ambas en el ámbito de la investigación, así mismo, pretende identificar el volumen de producción de artículos bajo este contexto y el aporte significativo para las próximas investigaciones. A partir de este análisis se procura encontrar la relación que existe entre ambas variables, toda vez que su fusión e interacción permita resolver dificultades que enfrenan las organizaciones respecto a la tendencia dinámica y de constante cambio que presenta el contexto económico, social y tecnológico del presente siglo. Los resultados de este análisis están basados en una muestra de 118 artículos y se contempla información relacionada a un periodo de 27 años, donde se observa una tendencia al declive de publicaciones a partir del periodo 2010 al 2014 hasta la fecha, por otro lado; la tendencia a citar estas fuentes se ha mantenido desde el 2015. Otros aspectos importantes que demuestran los resultados a través de los gráficos son la identificación de las características más significativas de la producción científica, los países que más publicaciones tienen y los artículos que más se han citado en los últimos 10 años. Este estudio identifica la necesidad de crear más contenido o incrementar la producción científica que incluya las variables CM y KM para consolidar la base teórica que aporte más información para futuros trabajos que contextualizan las exigencias de este siglo.
Study on Characteristics of an AC Sliding Discharge Plasma Actuator Operating at Different Pressures
Authors: Sun Qijie , Geng Xi , Li Zheng , Shi Zhiwei , Sun Zhikun , Cheng Keming
Published: January 2023

Dielectric barrier discharge (DBD) has been one of the most promising techniques for flow control, but the practical application needs a large plasma surface. A three-electrode sliding discharge plasma actuator (SDPA) can generate plasma filling the inter-electrode distance. In this study, the performance of an SDPA for practical flight at low pressures is reported. When the pressure decreases, plasma discharge becomes more intensive. Current peaks and power consumption of electrode 1 become higher at low pressure. Sliding discharge is fully developed at 54 kPa, and the plasma morphology resembles plumes. PIV results show vortex structures and an induced wall jet above the actuator surface. A ‘potential-arc-discharge’ is observed at 38 kPa, leading to an inhomogeneous surface temperature distribution and a velocity decrease of the jet.
Leadership and Turnover Intentions in a Public Hospital: The Mediating Effect of Organisational Commitment and Moderating Effect by Activity Department
Authors: Martins Patrícia , Nascimento Generosa , Moreira Ana
Published: January 2023

This research aimed to study the effect of leadership (transformational and transactional) on turnover intentions and whether this relationship is mediated by organisational commitment and moderated by the department of activity. To this end, it was hypothesized that: (1) leadership has a negative and significant association with turnover intentions; (2) leadership has a positive and significant association with affective organisational commitment; (3) organisational commitment has a negative and significant association with turnover intentions; (4) organisational commitment has a mediating effect on the relationship between leadership and turnover intentions; (5) the department to which the employee belongs has a moderating effect on the relationship between leadership and organisational turnover intentions. The sample consists of 477 participants working at the Hospital Professor Doutor Fernando Fonseca (HFF) in Portugal, performing their functions in several departments. This is a quantitative, correlational, and cross-sectional study. The results indicate that transformational leadership has a negative and significant effect on turnover intentions and a positive and significant effect on affective and normative commitment. Transactional leadership negatively and significantly affects all three components of organisational commitment. Affective and normative commitment has a negative and significant effect on turnover intentions. Calculative commitment has a positive and significant effect on turnover intentions. Affective commitment and calculative commitment have a partial mediating effect on the relationship between transformational leadership and organisational turnover intentions. The department to which the employee belongs does not have a moderating effect on the relationship between leadership and turnover intentions. It has been proven that leadership plays an extremely important role in the smooth running of this hospital unit.