bluuebunny/crossref_metadata_2025 huggingface dataset:
PREDIKSI ARAH DATANG BOLA MENGGUNAKAN KALMAN FILTER PADA ROBOT KIPER SEPAKBOLA
Authors: Daniyah Daniyah , Arifin Bustanul , Subroto Imam Much Ibnu
Published: April 2021

Robot kiper merupakan robot yang bertugas menjaga gawang dari masuknya bola oleh robot tim lawan. Permasalahan yang dihadapi dalam merancang robot kiper adalah bagaimana meningkatkan respon robot kiper terhadap bola sehingga kemungkinan terjadinya goal oleh robot lawan lebih sedikit. Robot kiper ini dirancang dengan menerapkan Kalman Filter. Kalman Filter merupakan suatu digital filter yang menggunakan algoritma dalam proses sinyal. Fungsi Kalman Filter sendiri adalah sebagai estimator stokastik untuk memprediksi arah bola terhadap robot kiper sepak bola beroda. Proses prediksi dapat dilakukan dengan mendeteksi bola terlebih dahulu sebagai acuan. Untuk pendeteksian bola sendiri menggunakan metode HSV yaitu Hue, Saturation, Value kemudian akan diolah menggunakan Kalman Filter sehingga mendapatkan nilai-nilai yang diperlukan dalam memprediksi arah datang bola. Penelitian ini menggunakan robot yang berdimensi 52 × 52 × 80 cm sesuai dengan aturan pada Kontes Robot Sepak Bola Indonesia Beroda dengan pemrograman Python dan menggunakan OpenCV untuk pengolahan citra-nya juga Filterpy untuk menerapkan fungsi Kalman Filter. Hasil dari penelitian ini adalah robot kiper yang menggunakan Kalman Filter dapat mengenali bola dari sudut pengujian yang sudah dilakukan dan dapat mengenali prediksi dari arah bola yang datang dari Kalman Filter yang digunakan pada robot kiper.
APLIKASI ARDUINO DAN REMOTE DESKTOP UNTUK PRAKTIK SOGI JARAK JAUH
Authors: Al Manshury Muhammad Said
Published: April 2021

Kondisi pandemi menyebabkan pembelajaran belum dapat dilakukan secara In Class Training. Termasuk pembelajaran yang berisi praktik. Untuk pembelajaran yang hanya berisi teori tanpa praktik, dapat dilakukan menggunakan aplikasi video conference seperti zoom, google meet, dan lain-lain. Sedangkan untuk pembelajaran yang mengandung praktik tidak bisa optimal jika hanya menggunakan  video conference. Untuk itu diperlukan suatu metode untuk mengatasi permasalahan tersebut. Permasalahan ini juga terjadi untuk praktik Sistem Otomasi Gardu Induk (SOGI). Pada praktik SOGI, peserta harus bisa mengoperasikan peralatan SOGI, yang memiliki tombol dan display. Salah satu solusi supaya praktik bisa dilakukan secara jarak jauh adalah dengan menggunakan aplikasi arduino dan remote desktop. Untuk aplikasi arduino dibangun dengan hardware arduino, software arduino dan Visual Basic. Sedangkan aplikasi remote desktop menggunakan anydesk atau aplikasi yang sejenis seperti team viewer dan lain-lain. Hardware yang diperlukan untuk praktik secara jarak jauh meliputi : arduino (mega 2560), button pusher, relay 5VDC, komputer, dan webcam. Hasil yang diperoleh dengan menerapkan aplikasi arduino dan remote desktop ini para peserta dari luar UPDL Semarang dapat mengoperasikan peralatan SOGI melalui komputernya masing-masing dengan tingkat keberhasilan 100% yaitu dapat mengoperasikan 10 tombol dan melihat display LCD peralatan SOGI (IED), sehingga praktik SOGI bisa dilakukan jarak jauh.
Biurokratyczne załatwianie spraw
Authors: Świderski Krzysztof
Published: April 2021

The article presents the issue of a bureaucratic disposal of matters by public administration authorities. The letter of dissatisfaction was introduced into Polish law as early as 1950. It was an expression of a negative attitude towards red tape. The prohibition of a bureaucratic disposal of matters is a guideline for the entire public sector. Bureaucracy is the negative behavior of officials: learned helplessness, routine, prejudices against applicants, assurance, conformism, and excessive formalism. The legislator’s pejorative assessment does not refer to bureaucracy itself, but to red tape as a dysfunction of bureaucracy. Red tape is the result of organizational culture. The article presents the model of Weberian bureaucracy and a critique of it. The provisions obliging officials to act in an fair, impartial, reasonable and proper manner are discussed, and the example is given of proper, open, efficient and independent European Union administration. The tool that determines bureaucracy is the document. The creation of excessive amounts of documents, as a manifestation of bureaucracy (red tape), is closely related to the development of office techniques. However, the development of information technology and the dissemination of electronic communication channels have changed the face of bureaucracy. The direct contact between an official with an applicant is changing into screen-level bureaucracy, with the claimant’s application being handled by the IT system. The official’s discretionary power has Hus been significantly reduced. The development of e-administration eliminates inappropriate actions of officials. However, a new type of bureaucracy is emerging by IT experts. Art. 227 of the Code of Administrative Proceedings can become a protective measure against theformalism of e-government.
Rafał Stankiewicz, Koordynacja w prawie administracyjnym, seria Monografie Prawnicze, Wydawnictwo C.H. Beck, Warszawa 2019, ss. 276, ISBN 978-83-8158-273-5
Authors: Jachimowicz-Jankowska Paulina
Published: April 2021

Rafał Stankiewicz, Koordynacja w prawie administracyjnym, seria Monografie Prawnicze, Wydawnictwo C.H. Beck, Warszawa 2019 ss. 276, ISBN 978-83-8158-273-5 (opr. Paulina Jachimowicz-Jankowska)
Webside manner: maskless communication
Authors: Mehta Ankit , Mathews Benji K.
Published: April 2021

Telemedicine has seen a rapid expansion lately, with virtual visits ushering in telediagnosis. Given the shift in the interpersonal and technical aspects of communications in a virtual visit, it is prudent to understand its effect on the patient-provider relationships. A range of interpersonal and communication skills can be utilized during telemedicine consultations in establishing relationships, and reaching a diagnosis. We propose a construct of “webside manner,” a structured approach to ensure the core elements of bedside etiquette are translated into the virtual encounter. This approach entails the totality of any interpersonal exchange on a virtual platform, to ensure a clinician’s presence, empathy and compassion is translated through this medium.
Fractional calculus, zeta functions and Shannon entropy
Authors: Guariglia Emanuel
Published: April 2021

This paper deals with the fractional calculus of zeta functions. In particular, the study is focused on the Hurwitz

ζ

\zeta

function. All the results are based on the complex generalization of the Grünwald-Letnikov fractional derivative. We state and prove the functional equation together with an integral representation by Bernoulli numbers. Moreover, we treat an application in terms of Shannon entropy.
Coloring variants of the Re3B type
Authors: Seidel Stefan , Pöttgen Rainer
Published: April 2021

The Re3B type, space group Cmcm, has boron-centered trigonal prisms as central building units and is one of the basic structure types with numerous binary and ternary representatives. The coloring of different atoms on the two crystallographically independent rhenium sites leads to a manifold of compounds with different bonding peculiarities that are rather isopointal than isotypic with the prototype. Typical compounds are the S-phase precipitate MgCuAl2, the silicide ScPt2Si or the iodide Th0.5Pb0.5I3 (PuBr3 type). Differences in size or composition might force symmetry reductions. This is discussed for YZn3 (space group Pnma) and the different coloring variants ScRhSi2 and TaNi2P which show different twists of the trigonal prisms. Striking singular representatives with lower symmetry structures are BaThBr6 (Pmma) and NbCo2B (P21/c) which allow different ordering/distortion patterns for the prisms. All these crystal chemical details are discussed on the basis of group subgroup schemes (Bärnighausen trees).
Considerations and Guidelines on Athletic Development for Youth Gaelic Athletic Association Players
Authors: Duggan John D. , Moody Jeremy , Byrne Paul , McGahan Jason H. , Kirszenstein Lukasz
Published: April 2021

Youth athletic development is important for sports performance and most importantly for life-long participation in sport and physical activity. The physical development of children and adolescents must be considered when programming different bio-motor qualities of physical training. The Gaelic Athletic Association and participation in Gaelic sports is an integral part of children and adolescents' formative years in Ireland with clubs the focal point of both urban and rural communities. This article will offer practitioners an overview of how to progress athletic development, physical literacy, and motor skills for preparation from grassroots to elite intercounty representation. Traditional athletic development models will be discussed and additional considerations, the importance of coaching styles will also be discussed. Practical recommendations are suggested such as the athletic motor skills competencies (AMSC) model (Figure 4), a differentiated movement matrix based on the AMSC from a movement motor skill and strength-based perspective (Tables 3 and 4). Practical guidelines and considerations on how to integrate strength and resistance training throughout stages of athletic development are also provided (Figure 7). This article aims to provide practitioners with an iterative, pragmatic, and evidence-based approach in the athletic development of youth Gaelic sports players from grassroots to elite level participation.
A Review of Striking Force in Full-Contact Combat Sport Athletes: Methods of Assessment
Authors: Lenetsky Seth , Uthoff Aaron , Coyne Joseph , Cronin John
Published: April 2021

With striking force playing such a critical role in the success of full-contact combat sports such as mixed martial arts, taekwondo, and boxing, coaches and scientists must be able to track this performance metric accurately and reliably. This review will cover practitioner understanding of key kinetic variables used in the assessment of striking important concepts relating to the validity, reliability, and reporting of meaningful performance changes in the assessment process, a critique of the methods used to monitor changes in striking forces, and provide practical recommendations for practitioners in the field. This understanding will help coaches and scientists assess and interpret the effectiveness of training.
Elusive Diagnosis of Superﬁcial Peroneal Nerve Entrapment Case report
Authors: Rapčan R. , Kočan L. , Alfredson H. , Sudzina R. , Rapčanová S. , Buriánek M. , Török P.
Published: April 2021

Isolated neuropathy of the superﬁcial peroneal nerve (SPN) is a relatively rare type of peripheral neuropathy. It is linked to the mechanical entrapment of the SPN in predisposed locations of its anatomical pathway. Associated clinical ﬁndings are insuﬃcient lifting of the latero-dorsal part of the foot, stepping on the lateral border of the foot, and commonly, a strong pain localized in the nerve dermatome.

Case report. We describe a case of a 14-year-old female patient with right leg pain lasting 24 months. Repeated neurological examinations with negative ﬁndings on electromyography (EMG) were performed. The patient underwent a Steindler surgery for a suspected diagnosis of a heel spur, without any improvement. Despite complex pharmacotherapy, chronic pain developed. The patient was unable to walk, being bound to a wheelchair. Amputation of her lower limb under the knee was also considered. SPN entrapment was diagnosed at a physical examination at EuroPainClinics. Decompression of the SPN under local anaesthesia was performed at the clinic.

Results. The symptoms improved immediately after the procedure, and following 2 months of rehabilitation, the patient was completely symptom-free. Her clinical state remains unchanged until this day.

Conclusions. SPN entrapment is not a common diagnosis in the group of pain syndromes. Regarding the lower limb, it is imperative to include it on the list of diﬀerential diagnoses in cases of pain and functional disorders of the lateral muscle groups of the calf and leg. In the case of SPN entrapment, EMG ﬁndings may be negative.
Adaptación marginal de coronas de disilicato de litio obtenidas mediante técnicas de escaneo (CAD/CAM): análisis in vitro con microscopía confocal
Authors: De Freitas Bruna Neves , Pintado-Palomino Karen , Honório Tonin Bruna Santos , Bastos Cruvinel Pedro , Macedo Ana Paula , Tirapelli Camila , Hirono Hotta Takami , Matsumoto Wilson
Published: April 2021

Objetivo. El objetivo de este estudio fue evaluar la adaptación marginal de coronas de disilicato de litio obtenidas mediante técnicas de escaneo (CAD/CAM), antes y después de la cristalización, a través de análisis in vitro con microscopía confocal (MC). Métodos. Fueron confeccionadas 16 réplicas en poliuretano a partir de la pieza 1.4, de modelo typodont, tallada para corona total. Las réplicas fueron divididas en dos grupos, de acuerdo a la técnica de escaneo: Técnica Indirecta (Grupo IND, n=08), donde modelos de yeso fueron escaneados con escáner de laboratorio (inEos X5, Sirona Dental Systems) y Técnica Directa (Grupo DIR, n=08), donde modelos typodont fueron escaneados con escáner intraoral (CEREC BlueCam, Sirona Dental Systems). A seguir, se fresaron (inLab MC XL, Sirona Dental Systems) coronas en disilicato de litio (IPS e.max CAD, Ivoclar Vivadent) y se adaptaron a las réplicas. Se evaluó la adaptación marginal con análisis de MC en dos momentos, antes y después de la cristalización del disilicato de litio. Los datos fueron analizados con la prueba de Mann-Whitney, t de Student y Wilcoxon (α= 0,05). Resultados. Hubo una diferencia estadísticamente significativa en la adaptación marginal horizontal entre los grupos IND y DIR después de la cristalización (p=0,05). En el grupo IND, la comparación de la adaptación marginal vertical antes y después de la cristalización mostró una diferencia estadísticamente significativa (p=0,038). Conclusiones. Las coronas de disilicato de litio obtenidas mediante escaneo directo (CAD/CAM) presentaron menor desajuste marginal vertical. La etapa de cristalización afectó la adaptación marginal de las coronas.
Prevalencia de anticuerpos contra Chlamydophila abortus en bovinos de crianza extensiva de tres distritos de Ayacucho, Perú
Authors: Loli-Pin Jean Pierre , Villacaqui-Ayllón Eglinton , Morales-Cauti Siever
Published: April 2021

El objetivo del estudio fue determinar la prevalencia de anticuerpos contra Chlamydophila abortus en el ganado bovino de los distritos de Coracora, Chumpi y Pullo de la provincia de Parinacochas, departamento de Ayacucho, Perú. Los animales eran criados de forma extensiva y bajo monta natural. Se tomaron 184 muestras de sangre en bovinos mayores de 4 meses indistintamente del sexo. La detección de anticuerpos contra C. abortus se hizo con un kit comercial de ELISA indirecto. Se obtuvo una prevalencia corregida de 40.34 ± 7.06% con diferencia significativa entre distritos (p<0.05), siendo menor en Coracora (40.29 ± 8.89%) y mayor en Pullo (56.05 ± 7.15%, y sin diferencias significativas por efecto del sexo, raza, categoría animal y estado reproductivo. La alta prevalencia encontrada confirma la diseminación del patógeno en la población bovina de los distritos evaluados.
Evolución de la dactilogirosis (monogeneos) en branquias de alevinos de gamitana (Colossoma macropomum) en dos medios de crianza: acuático artificial y semi-natural
Authors: Rondón E. Juan , Villanueva C. César , Gavidia C Cesar , Puicón N. Víctor
Published: April 2021

El objetivo del estudio fue determinar la evolución de la infestación por monogeneos de la familia Dactylogiridae en branquias de alevinos de gamitana (Colossoma macropomum) criados en jaulas en un medio acuático artificial y semi-natural. Se evaluaron 120 alevinos de 45 días de edad un peso promedio de 3.05 + 0.58 g, y longitud total promedio de 5.23 + 0.51 cm. Los peces fueron distribuidos en dos jaulas flotantes (60 alevinos por jaula), la primera ubicada en un estanque de tierra en una piscigranja con crianza semi-intensiva (medio artificial), y la segunda en un embalse (medio semi-natural). Ambos grupos recibieron similar régimen alimenticio. Los grados cualitativos de infestación considerados fueron leve, moderado y severo, según la cantidad de parásitos monogeneos encontrados en los cortes de branquias evaluados por microscopía directa. Los alevinos estuvieron libres de la infestación parasitaria al inicio del experimento, posteriormente se evaluaron 12 ejemplares por grupo a los 15, 30, 45, 60 y 90 días. A los 15 días, la infestación aumentó a grado leve en el medio semi-natural y continuó como negativo en el medio artificial; finalmente se tornaron a grado leve en ambos medios, hasta finalizar el experimento, sin haber diferencia significativa entre grados de infestación en ambos grupos. Se concluye que ambos medios acuáticos no representan un riesgo para el desarrollo de infestaciones moderadas o severas por monogeneos en branquias que afecten las poblaciones de alevinos de gamitanas.
Efecto de cinco niveles de balance electrolítico dietario en el crecimiento, características de carcasa y metabolitos de suero sanguíneo del cuy (Cavia porcellus)
Authors: Paredes Manuel , Mantilla José , Bustamante Irma , Mantilla Joe , Cayotopa José , Hoban Cristian , Ortiz Pedro , Mustafa Arif
Published: April 2021

Se realizó un estudio para determinar los efectos del balance electrolítico dietario (BED) sobre el rendimiento productivo, características de la canal y metabolitos sanguíneos del cuy en una granja experimental de Cajamarca, Perú. Se utilizaron 150 cuyes machos distribuidos en cinco tratamientos con cinco niveles de BED: 100, 200, 300, 400 y 500 mEq/kg. Cada tratamiento tuvo seis repeticiones y cada repetición con cinco cuyes/poza. Los cuyes consumieron alimento concentrado durante 42 días. Al término del periodo experimental se sacrificaron seis cuyes por tratamiento para determinar el rendimiento de carcasa, pesos relativos de las vísceras y concentración de metabolitos sanguíneos. Se encontraron diferencias (p<0.05) en el peso corporal final, ganancia de peso e índice de conversión alimenticia a favor de cuyes con BED de 300 mEq/kg. No hubo diferencias significativas entre tratamientos en las características de la canal ni en los valores de metabolitos en sangre, excepto la creatinina. Según los resultados de este estudio, el cuy podría ser alimentado con 300 mEq/kg de BED, con resultados satisfactorios de crecimiento.
O ensino remoto e as estratégias dos pais em manter os filhos conectados à escola pública
Authors: Cruz Jacilene Silva da , Vieira Roberta Fernandes , Ferst Enia
Published: April 2021

Este artigo tem como objetivo verificar se os pais de alunos do Ensino Médio se preocuparam mais com a educação escolar de seus filhos durante o ensino remoto Para isso foi feita uma pesquisa biográfica-documental e de campo através de questionário na plataforma Google Forms. Foram entrevistados 30% dos pais de alunos do 2º ano do Ensino Médio de uma escola pública estadual do centro da cidade de Boa Vista/Roraima. Os dados obtidos foram interpretados a partir de uma perspectiva qualitativa fenomenológica. Este estudo conclui que há sim uma preocupação em manter os alunos conectados à escola durante o período pandêmico, mesmo através de ações aparentemente simples, os pais se envolvem mais com os assuntos relacionados à educação. Em relação ao ensino remoto fica evidente que não é eficaz, não satisfazendo e não atendendo às necessidades do momento, isso fica evidenciado tanto pelas respostas diretas quanto pela quantidade significativa de pais que não responderam às perguntas referentes ao ensino nessa modalidade. Assim, para vencer a nova ordem social, os pais buscaram meios para auxiliar os filhos dentro das possibilidades de cada um.
Road transport vibration stress impact on ‘Palmer’ mangoes quality and shelflife
Authors: Costa Josenara Daiane de Souza , Figueiredo Neto Acácio , Olivier Nelson Cárdenas , Irmão Marcos Antônio da Silva , Costa Marylia de Sousa , Gomes Josivanda Palmeira
Published: April 2021

Abstract Studying the causes of postharvest fruit loss is important to avoid reduction of quality and quantity for the consumer due, for example, to the influence of frequent impacts from vibrations during transportation. In this sense, this study evaluates the storage quality of ‘Palmer’ mangoes after being subjected to different simulated road transport vibrations. Vibration was simulated from the analysis of the profile of the frequencies generated in road transport of fruit, determined in a tractor trailer. ‘Palmer’ mangoes stored after vibration stress wereevaluated for: mass loss, absorbance difference index (IAD), peel and pulp browning index (BI), pulp firmness, soluble solids content, and titratable acidity. The development of a vibration machine made it possible to satisfactorily simulate specific vibration frequencies. Vibration stress during simulated transport led to accelerated weight loss, decreased pulp firmness, and peel browning in ‘Palmer’ mangoes.
Characterization of fruits of varieties of mango (Mangifera indica) conserved in Peru
Authors: Coral Lady Laura Tuisima , Escobar-Garcia Hector Alonso
Published: April 2021

Abstract The department of Piura is the main mango producer in Peru accounting for 66.7% of the national crop. The objective of the study was to characterize the fruits of forty varieties of mango preserved since 1969 in northwestern Peru. The fruits were harvested at the El Chira Agrarian Experimental Station, Department of Piura from December 2019 to January 2020. Thirteen quantitative fruit variables were evaluated: width, thickness, length, weight, seed width, seed thickness, seed length, percentage of seed, percentage of fresh skin, percentage of pulp, texture, °Brix, and pulp / seed ratios. The varieties with the highest percentage of pulp were Tommy Atkins, Haden x carabao 1, Irwin, and Jaffra, the latter was also the variety with the highest pulp / seed ratio (17.0). The varieties with the highest ° Brix were Blacman (21.3 ° Brix) and Julie (22.0 ° Brix). Knowledge of the fruit characteristics is essential for proper selection and use by the industry, especially those with a higher pulp weight to obtaining higher yields in processing.
Hannah Arendt e a intencionalidade das aparências
Authors: Dias Lucas Barreto
Published: April 2021

Resumo Neste texto, investiga-se o conceito de intencionalidade presente no pensamento de Hannah Arendt. Termo proveniente da fenomenologia husserliana, a intencionalidade designa que a consciência sempre se movimenta em direção a um objeto, de modo que, para Husserl, se trata aqui de um atributo do ego transcendental. Arendt, em sua obra póstuma, faz um deslocamento do conceito: a intencionalidade passa a ser compreendida não apenas como algo vinculado a um sujeito, mas, sobretudo às aparências. Desse modo, assim como o sujeito coloca em questão o objeto visado pela consciência, também o fenômeno pressupõe uma subjetividade embutida, isto é, as aparências se doam intencionalmente àqueles que captam suas aparições. Essa relação intencional, todavia, só faz sentido, no pensamento de Arendt, caso se coloque em questão a pluralidade humana como conjunto de seres capazes de apreender as aparências, a partir de uma experiência que só é possível mediante a própria pluralidade. Assim, a pensadora rechaça o sujeito cognoscente isolado como critério de verdade e sentido, proporcionando uma interpretação da relação homens e mundo, como perspectiva pela qual se pode chegar a uma compreensão intersubjetiva da realidade.
Exposição potencial a baixas doses de cromo por via oral e mortalidade por câncer de estômago na população do interior do Estado de São Paulo, Brasil
Authors: Oliveira Fabio Luiz Vieira de , Kuno Rúbia , Nascimento Felipe Parra do , Gouveia Nelson
Published: April 2021

Resumo: Concentrações de cromo total entre 0,45 e 110µg/L têm sido detectadas, no Sistema Aquífero Bauru (SAB) no Estado de São Paulo, Brasil, excedendo, algumas vezes, o padrão de qualidade adotado pela legislação brasileira, que é de 50μg/L. Segundo a Companhia Ambiental do Estado de São Paulo (CETESB), parte do cromo é composta pela forma hexavalente [Cr(VI)], que apresenta controversas evidências quanto à carcinogenicidade por via oral. Este artigo tem como objetivo avaliar o efeito da exposição ao Cr(VI) em baixas doses na mortalidade por câncer gástrico da população entre 15 e 75 anos ou mais, que consumiu água do SAB, no período entre 2004 e 2015. Foi realizado um estudo ecológico em 326 municípios situados no Planalto Ocidental Paulista e que usam água do SAB. As associações foram estimadas pelo modelo de regressão linear, utilizando-se indicadores de exposição ao cromo (proxy) e razão de mortalidade padronizada (RMP) para as neoplasias gástricas como variável resposta. O Índice de Desenvolvimento Humano Municipal (IDHM) foi empregado para controlar possíveis diferenças socioeconômicas da população investigada. A RMP estimada para o câncer gástrico correspondeu a 79% dos óbitos esperados, sendo que o risco foi menor nos municípios que têm água tratada pela Companhia de Saneamento Básico do Estado de São Paulo (SABESP), com especial atenção para a população feminina (β = -0,146; IC95%: -0,270; -0,021; p = 0,022). Embora os dados da pesquisa sejam limitados, em 77 (23,6%) dos municípios avaliados, houve aumento do risco de câncer gástrico. Dentre esses, quase 70% se abastecem de manancial subterrâneo, associado às bacias hidrográficas com anomalias geoquímicas de Cr(VI).
Como a comunidade internacional da medicina de precisão tem se posicionado diante dos desafios impostos pela pandemia da COVID-19?
Authors: Silva Renan Gonçalves Leonel da , Iriart Jorge Alberto Bernstein
Published: April 2021

Medicina de precisão pode ser definida como um movimento de transformação da biomedicina contemporânea que orienta a atividade de pesquisa acadêmica, modelos de negócios e o desenvolvimento de produtos e serviços de saúde desenhados individualmente para o usuário, baseado em informações genéticas e outros marcadores biomédicos dos pacientes. Ao longo dos últimos anos, essa comunidade tem sido bastante atuante no cenário científico internacional. No entanto, durante a pandemia da COVID-19 ainda não ficou claro quais posicionamentos ou estratégias têm sido adotadas por esses grupos para o enfrentamento da crise sanitária. O objetivo deste artigo é compreender como a comunidade internacional da medicina de precisão está reagindo à pandemia da COVID-19, e em que estão baseadas as suas abordagens e potenciais soluções sugeridas para a mitigação dos efeitos negativos causados pelo aumento das infecções pelo novo coronavírus. Para tanto, foi feita pesquisa documental em 28 documentos provenientes de 18 fontes selecionadas, em que analisou-se as narrativas difundidas pelos profissionais da medicina de precisão em artigos científicos, editoriais, comentários, perspectivas, notícias de jornais e boletins e conferência virtual da Coalizão de Medicina Personalizada (PMC, em inglês). Com isso, buscou-se compreender como esses grupos imaginam uma nova configuração sociotécnica para o enfrentamento da pandemia e de seus efeitos.
PROJETOS DE VIDA DE JOVENS EGRESSOS DE MEDIDAS SOCIOEDUCATIVAS
Authors: Costa Cibele Soares da Silva , Alberto Maria de Fatima Pereira
Published: April 2021

Resumo O objetivo deste artigo é analisar as contribuições dos programas de acompanhamento aos egressos de medida socioeducativa de internação para a construção do projeto de vida. Foi realizada uma pesquisa com nove jovens egressos em dois estados: Bahia e Rio Grande do Sul. Utilizou-se uma entrevista aberta individual e os dados foram analisados através da Análise Temática de Conteúdo, obtendo-se a posteriori as classes: Sentidos sobre a participação nos programas de acompanhamento aos egressos de MSE e Projetos de vida dos jovens. Identificou-se que os jovens elaboram sentidos positivos sobre a participação nos programas, considerando-os como possibilidade para mudar de vida, diferenciando-se do cumprimento da medida socioeducativa por não possuir uma dimensão sancionatória. Conclui-se que a participação nos programas de acompanhamento aos egressos de MSE representa a possibilidade dos jovens contarem com o auxílio das equipes técnicas para pensarem em seus planos para o futuro e adquirir os elementos necessários para efetivá-los.
The impact of alternative assets on the performance of Brazilian private pension funds
Authors: Flores Francis Amim , Campani Carlos Heitor , Roquete Raphael Moses
Published: April 2021

ABSTRACT This article assesses the impact of alternative assets on the performance of Brazilian private pension funds. Few studies touch on this topic in Brazil and most only investigate the addition of alternative assets and their impact on the performance. The market of open private pension funds in Brazil has been growing rapidly in recent years and gaining much relevance, especially after the announcement of the reformulation of the Brazilian pension system. In 2018, the Free Benefit Generating Plan (PGBL) and the Free Benefit Generating Life (VGBL) represented more than 94% of total assets in their sector. The Brazilian specially constituted investment funds (FIEs) of PGBL and VGBL private pension plans are characterized by their dependence on fixed income assets. Brazil currently faces an unprecedent low interest rate scenario - which, following a worldwide panorama, seems to be set for a long time - and pension fund managers must search for alternative investments that aggregate both risk premia and diversification. The results of this study may support managers in this little-discussed matter. We compare the performance of FIEs without additional alternative assets versus the portfolio with alternative assets, adding a hedge fund index, an equity mutual funds index, a commodity index, an electric power index, a public utilities index, a gold index, and a real estate index. Several performance measures were used, considering Brazilian regulations and a rebalancing strategy. Our results showed that almost all alternative assets used in this study improved the performance of the Brazilian FIEs of PGBL and VGBL private pension plans, especially the public utilities index and the hedge fund index. Some even improved the portfolio tail risk.
The impact of MILA market-maker facility on volatility of the Colombian stock market
Authors: Lukanima Benedicto Kulwizira , Gómez-Bravo Yuli Paola , Sanchez-Barrios Luis Javier
Published: April 2021

ABSTRACT In 2014, the Colombian Stock Exchange commenced the implementation of its market-maker facility (MMF), aiming at improving market efficiency. This paper examines the impact of the MMF program on three volatility-related aspects: volatility persistence, risk premium, and information asymmetry. This paper provides new insights about the anticipated outcomes of Mercados Integrados Latinoamericanos (MILA) reforms, specifically the MMF on the volatility of the Colombian stock market. This topic has not been fully addressed in the existing literature. This study, therefore, provides useful information for regulators and policy makers, in endeavors to address key issues raised during the World Economic Forum (WEF) of 2016. This paper poses a challenge to policy makers and stock market regulators in Colombia to revisit the reform program and address the factors limiting the effectiveness of market reforms. This paper provides justification for replicating the study to cover other MILA countries due to existing differences in some domestic market policies and structures. The paper employs conditional variance models for measuring volatility persistence, risk premia, and information asymmetry. The models are employed on the COLCAP stock index (Colombia) observed from January 17, 2008 to May 30, 2019. Observations are divided into two samples - pre- and post-MMF. This paper provides evidence of the impacts of the MMF reforms in the Colombian stock market. Specifically, the MMF seems to have an impact on the following aspects: (i) the magnitude in which current returns depend on previous returns has increased; (ii) investment portfolio returns, which are generally low, have declined after the MMF, leading to less risk compensation; (iii) the MMF does not seem to have affected the volatility of market returns and information asymmetry; (iv) volatility persistence increased in magnitude.
Students’ experience with literature in medical education
Authors: Mega Marina Nahas , Bueno Bárbara Cazula , Menegaço Eduarda Campos , Guilhen Mariani Pereira , Pio Danielle Abdel Massih , Vernasque Juliana Ribeiro da Silva
Published: April 2021

Abstract: Introduction: The National Curricular Guidelines (NCG) for medical school bring the teaching of Humanities, among them Literature, as a way to overcome the biomedical model. Literature can strengthen compassion directed to the ‘other’. It starts with a curriculum organized by active teaching-learning methodologies. Objective: This study aims to understand the experiences of students from a Medical School in the interior of São Paulo who had contact with literary texts in the beginning of medical school, creating a representative model based on the experience. Method: This is a qualitative research guided by the Grounded Theory. The data collection was carried out through semi-structured interviews with undergraduate students who were randomly chosen from all years of the Medical School. The only inclusion criteria was the participation in groups coordinated by a teacher who had used literature as a teaching strategy. Twelve interviews were carried out, transcribed and codified. The sampling was performed by theoretical saturation. Results: The created categories were: 1. “Identifying the importance of the literature and Arts in Medical School, seeking a rupture from the biomedical model, while improving empathy and the humanization of care”; 2. “Reflecting on the use of artistic tools to learn practical contents in Medicine and to provide psychosocial knowledge”; 3. “Proposing a possible curricular systematization, considering active methodologies and other artistic forms”; 4. “Recalling the tales that are more often associated to the student’s personal interest, which can promote the integration with all the acquired knowledge”. Based on these categories, it was possible to create the representative model of the experience that relays the students’ satisfaction with literature in medical education, enhancing the humanization of care; however, there is a need for curriculum homogenization, aiming at organizing the activity and the learning opportunity for others students. Conclusion: The model comprises the idea that literature enhances the humanization of care and is able to establish a rupture from the biomedical model. The study potential lies in proposing strategies to the community and academic management, aiming to strengthen humanization in curricular perspective of medical training.
O uso de metodologias ativas de ensino-aprendizagem em pediatria: uma revisão narrativa
Authors: Faria Bárbara Caroline Dias , Amaral Clésio Gontijo do
Published: April 2021

Resumo: Introdução: O modelo tradicional de ensino médico possui uma ideia biocêntrica dos problemas de saúde, hipervalorizando os aspectos biológicos do paciente, sem considerar os demais aspectos envolvidos no processo saúde-doença. Esse método é centrado no professor, e o aluno atua como receptor passivo do conhecimento. Em contrapartida, nas metodologias ativas, o estudante possui papel ativo no processo de ensino-aprendizagem, construindo um conhecimento crítico e reflexivo. Objetivo: Este estudo teve como objetivos analisar a importância das metodologias ativas no ensino de Pediatria I do curso de Medicina da Universidade Federal de Minas Gerais (UFMG) e propor adaptações que permitam a aplicação dessas metodologias no período de ensino remoto emergencial (ERE). Método: Trata-se de uma revisão narrativa, com dados obtidos de forma independente pelos autores, por meio de busca abrangente e não sistemática no PubMed e na SciELO. Primeiro, realizaram-se a busca e a análise de dados das principais metodologias ativas, e, posteriormente, os achados foram aplicados à disciplina de Pediatria I do curso de Medicina da UFMG, incluindo suas adaptações para a implementação no ERE. Resultados: Analisaram-se a problematização, a aprendizagem baseada em problemas e o fishbowl como recursos didáticos das metodologias ativas. Esses métodos reforçam a curiosidade, a autonomia, a motivação e as capacidades crítica e reflexiva do aluno. Ademais, promovem integração entre teoria e prática, incentivo do trabalho em equipe e estímulo para o estudante se conscientizar sobre os problemas sociais existentes. Conclusão: Assim, o uso das metodologias ativas no ensino em Pediatria I possibilita alcançar os objetivos da disciplina, tanto no modo presencial quanto no ERE, e atingir as expectativas das diretrizes brasileiras sobre a formação médica.
Going the Extra Mile: Impact of Individuals’ Behavior on Information Technology Governance
Authors: Wiedenhöft Guilherme Costa , Luciano Edimara Mezzomo
Published: April 2021

ABSTRACT Objective: this work emphasizes the information technology governance (ITG) behavioral expression and aims to identify whether individual behavior contributes to the increase of the perceived maturity of the ITG mechanisms. The organizational citizenship behavior (OCB) concept was the base to develop a model of relations between individual behavior and ITG maturity. Methods: we carried out a survey with 243 IT personnel of the executive branch of a Brazilian state government. We used partial least squares as data analysis technique. Results: the findings show the existence of a positive and significant relationship between the variable spirit of initiative and the perceived maturity of the ITG mechanisms. Conclusions: the impact of ITG changes in individuals’ behavior needs to be considered, which reinforces that ITG is a critical resource for implementing public policies and executing governmental strategies. In order to raise the IT governance maturity, managers should foster the spirit of initiative in their teams, acting on their antecedents such as feelings of control, complexity, self-efficacy, and responsibility for changes. Consequently, individuals can make a deliberate decision, constantly evaluating the likely outcomes of their behaviors in favor of the adoption of ITG mechanisms.
Afirmação Fânica: Aleturgia em um Fandom de Música Indie
Authors: Cavalcanti Rodrigo César Tavares , Souza-Leão André Luiz Maranhão de , Moura Bruno Melo
Published: April 2021

ABSTRACT Context: highly identified with the genre, indie fans are engaged and productive, especially in virtual communities where they circulate opinions and share experiences. Objective: since relations mediated by consumption provide conditions for constituting subjectivities, we rely on Foucault’s theory with the aim of analyzing how the interactions of indie music fans evidence an alethurgical process of subjectivation. Methodology: to do this, we performed a netnography on a large global forum for indie music discussion. Results: results show a cultural configuration in which the communal sense legitimize conducts, based on emotional testimonies and manifestations of expertise, which establish the very condition of fanity associated with the capacity of its members to outline the fan object, develop a fan authority and then to position themselves in relation to the market logic in which the genre is inserted. Conclusion: thus, we conclude that indie music fans perform an alethurgy of affirmation. The study innovates by adopting the concept of alethurgy as a means of analyzing the subjectivation of fans, which is evidenced as a theoretical gap in the field of CCT.
Boundary-Crossing Strategies: Managing Macro Policies in a Federal Government
Authors: Cavalcante Pedro , Lotta Gabriela Spanghero
Published: April 2021

ABSTRACT Objectives: this paper aims to analyze boundary-crossing strategies, henceforth BCS, a complex and relatively new coordination trend in public administration. To do so, we investigated how three prioritized coordination policies from different sectors were designed and implemented in Brazil. Methods: following a literature review on BCS, the paper employs content analysis of the programs’ legislation and government white papers. To understand how the programs actually functioned, we interviewed key government stakeholders. Results: they suggest that two macro policies incorporated most of the boundary-crossing features in their formal design and, more importantly, implementation processes. However, the degree to which these characteristics are present varies according to the research focus or the interviewee’s position. Conclusions: main findings of BCS strategy are that policy effectiveness and continuity depend on the consensus of different stakeholders about policy goals; the empowerment of leaders; adoption of new coordination instruments; and continuing policy prioritization. Finally, by exploring the adaptation of an international trend to the Brazilian public administration context, the paper shows crucial insights for innovation in terms of policy coordination and implementation.
PUXANDO A FUMAÇA E SOLTANDO PRO AR Consagração e silêncio em Pixinguinha e Dorival Caymmi
Authors: Queiroz Vítor , Cesar Rafael do Nascimento
Published: April 2021

Este artigo trata das correlações entre raça, envelhecimento e silêncio presentes nas trajetórias de dois artistas negros da música popular brasileira: Alfredo da Rocha Viana Filho, ou Pixinguinha, e Dorival Caymmi. Recuperando alguns momentos decisivos de seus processos de consagração perante a crítica especializada e a historiografia da música popular, o artigo procura evidenciar como o silêncio acerca de determinadas marcas sociais de ambos, notadamente a cor, figurou como uma dimensão crucial de suas experiências raciais. Nas biografias e entrevistas existentes, salvo raríssimas exceções, Pixinguinha e Caymmi não são identificados como negros, ao passo que abundam referências à idade e à genialidade deles. Além disso, a não enunciação da negritude, analisada no contexto específico de suas trajetórias como instrumentistas e compositores, pode ser entendida também como estratégia, empregada por eles próprios, para tentar burlar certos constrangimentos decorrentes do racismo presente na sociedade brasileira.
Effect of Acidosis on the Properties of the Glutaminase mRNA pH-Response Element Binding Protein
Authors: LATERZA OMAR F. , CURTHOYS NORMAN P.
Published: April 2021

The pH-responsive stabilization of the rat renal glutaminase (GA) mRNA during metabolic acidosis is mediated by a pH-response element (pH-RE). The primary pH-RE within the GA mRNA consists of a direct repeat of an 8-base adenosine and uridine—rich sequence, which binds a specific cytosolic protein, the pH-response element binding protein (REBP). The functional analysis of this system was performed in LLC-PK1-F+ cells, a pH-responsive line of porcine proximal tubule-like cells. Cytosolic extracts of LLC-PK1-F+ cells also contain a protein that binds with high affinity to the rat GA mRNA pH-RE. The apparent binding of this protein is increased threefold in cytosolic extracts prepared from LLC-PK1-F+ cells that were grown in acidic medium (pH = 6.9, HCO3- = 10 mM). Extracts prepared from the renal cortext of rats that were made acutely acidotic also exhibit a similar increase in binding to the RNA probe that contains the direct repeat of the pH-RE. The temporal increase in binding correlates with the temporal increase in GA mRNA. Scatchard analysis indicates that the increased binding is due to an increase in both the affinity and the maximal binding of the pH-REBP. Thus, increased binding of the pH-REBP to the GA mRNA may initiate its stabilization and increased expression during acidosis.
Activation of DNA Synthesis and AP-1 by Profilin, an Actin-Binding Protein, via Binding to a Cell Surface Receptor in Cultured Rat Mesangial Cells
Authors: TAMURA MASAHITO , YANAGIHARA NOBUYUKI , TANAKA HIROSHI , OSAJIMA AKIHIKO , HIRANO TAKESHI , HIGASHI KEN , YAMADA KENNETH M. , NAKASHIMA YASUHIDE , HIRANO HIDEYASU
Published: April 2021

Profilin is known to bind to actin monomers (to regulate actin polymerization) and to phosphatidylinositol-4,5-bisphosphate (to inhibit hydrolysis by unphosphorylated phospholipase C-γl). It was recently reported that profilin is overexpressed in glomerular mesangial cells (MC) of rats with anti-Thy-1.1-induced glomerulonephritis and is accumulated in the extracellular space around MC. In this study, the biologic activities of extracellular profilin were examined. Scatchard analysis indicated the existence of a single class of cell surface binding sites, with similar equilibrium dissociation constants for purified splenic profilin and recombinant profilin, in cultured rat MC. Profilin increased [3H]thymidine incorporation in a dose-dependent manner and produced additive effects on platelet-derived growth factor-induced [3H]thymidine incorporation. Profilin increased AP-1 DNA-binding activity in a concentration-dependent (ED50 = 30 nM) and time-dependent manner after transient c-jun gene expression, as measured using gel-shift assays and competitive reverse transcription-PCR. Pretreatment of profilin with an anti-profilin inhibitory antibody suppressed profilin-induced AP-1 activation and [3H]thymidine incorporation. Furthermore, profilin induced rapid transient activation of protein kinase C, and staurosporine and H-7 reduced the profilin-induced activation of AP-1, suggesting protein kinase C-dependent activation of AP-1. These findings indicate that profilin in the extracellular space can bind to cell surface receptors of MC and act as an inducer of signal transduction. These results suggest that extracellular profilin may be involved in the progression of glomerular diseases, by affecting cell growth.
Type 2 Diabetic Patients with Nephropathy Show Structural—Functional Relationships that Are Similar to Type 1 Disease
Authors: WHITE KATHRYN ELIZABETH , BILOUS RUDOLF WILLIAM
Published: April 2021

Glomerular structural—functional relationships were investigated in 21 type 2 diabetic patients with proteinuria. Structural parameters were quantified using both light and electron microscopy and standard stereologic techniques. Data were also available on 14 nondiabetic subjects. Mesangial and matrix volume fractions and glomerular basement membrane (GBM) width were increased in type 2 patients when compared with nondiabetic subjects (mean ± SD: 0.45 ± 0.13 versus 0.18 ± 0.03, P < 0.001; 0.28 ± 0.09 versus 0.10 ± 0.02, P < 0.001; and 665 ± 138 versus 361 ± 51 nm, P < 0.001, respectively). An increase in mesangial volume fraction was associated with high levels of proteinuria and low creatinine clearance (r = 0.64, P = 0.002; r = -0.58, P = 0.006, respectively). GBM width and mesangial foot process width (FPWmes) also correlated with proteinuria (r = 0.58, P = 0.006; r = 0.60, P = 0.004, respectively). Volume fraction of interstitium correlated with creatinine clearance (r = -0.58, P = 0.006). Patients had previously been defined by light microscopy as having either diffuse or nodular glomerulosclerosis; those with nodules had larger mesangial and matrix volume fractions and more proteinuria than those classified as diffuse (mean ± SD: 0.51 ± 0.12 versus 0.36 ± 0.08, P = 0.007; 0.32 ± 0.08 versus 0.21 ± 0.05, P = 0.003; median, range: 4.3, 1.1 to 9.6 versus 1.1, 0.9 to 12.7 g/24 h, P = 0.027). Creatinine clearance did not differ significantly between the groups. Type 2 diabetic patients with proteinuria have established glomerulopathy, which is more advanced in those with nodular glomerulosclerosis. Creatinine clearance correlated with both mesangial and interstitial expansion, whereas proteinuria correlated only with glomerular pathology. These results suggest that type 2 patients with advanced nephropathy have structural—functional relationships similar to type 1, consistent with a common pathogenesis, and strongly support an important role of the tubulointerstitium in the role of renal impairment.