bluuebunny/crossref_metadata_2025 huggingface dataset:
Vibration-Isolation Performance of a Pile Barrier in an Area of Soft Soil in Shanghai
Authors: Ma X. F. , Cao M. Y. , Gu X. Q. , Zhang B. M. , Yang Z. H. , Guan P. F.
Published: October 2020

Environmental vibration caused by traffic can affect the normal operation of precision instruments, and vibration-isolation measures should be taken to reduce such negative effects. The engineering background of this paper is a hard-X-ray tunnel under construction in Shanghai, China. First, field vibration measurements are used to study the characteristics of the ground traffic, maglev, subway, and other vibration sources near the tunnel, as well as the laws governing the propagation of vibration waves in the surface and soil layer. The finite-element modelling is then used to establish a two-dimensional numerical model for the field conditions, and the numerical results are compared with the field vibration measurements to validate the applicability of the numerical model for assessing the effects of environmental vibration. Finally, how the parameters of a pile-barrier vibration-isolation system, a vibration-isolation measure used widely for tunnels, influence its performance is studied. The results show the following: with increasing distance from the vibration source, the amplitude of the vibration acceleration decreases gradually, and the high-frequency part of the vibration wave is attenuated rapidly, whereas the low-frequency part is attenuated very little. The vibration-isolation effect of the pile barrier is directly proportional to the elastic modulus of the pile body, the pile length, and the hollow ratio of the pile, and inversely proportional to the stiffness of the filling material. The pile diameter, pile row number, and row spacing have little influence on the vibration-isolation effect. Increasing the pile diameter attenuates the acceleration amplitude somewhat around 10 Hz but has no effect on it around 5 Hz. Overall, the present numerical method is well suited to evaluating environmental vibration problems.
Outage Probability and Normalized SINR-Based Power Allocation over Rician Fading Channels
Authors: Ho Danh H. , Gulliver T. Aaron
Published: October 2020

This paper considers power allocation in cellular networks over Rician fading channels. The goal is to improve the power consumption and energy efficiency as well as satisfy as many users as possible subject to user outage probability and normalized signal to interference plus noise ratio (SINR) constraints. The exact outage probability over Rician fading channels is determined using the moment-generating function (MGF). Further, upper and lower bounds on the outage probability are derived. These are used to characterize the relationship between outage probability and normalized SINR in Rician fading channels. Power allocation algorithms for power minimization and energy efficiency are proposed. Simulation results are presented to compare the performance of the proposed schemes with existing methods in terms of power consumption, throughput, energy efficiency, outage probability, and number of unsatisfied users.
Correlation between the Characteristic Flavour of Youtiao and Trans Fatty Acids Assessed via Gas Chromatography Mass Spectrometry and Partial Least Squares Regression Analyses
Authors: Yang Xuelian , Zhang Xiangyu , Xie Jianchun , Yang Dongdong , Wang Chengtao , Lozano Jesús
Published: October 2020

This study aimed to analyse trans fatty acid (TFA) levels and key volatile flavour substances in fried youtiao prepared using five common edible oils and the relationship between TFAs and key volatile flavour substances via partial least squares regression (PLSR) analysis. Total TFA levels were the highest on using rapeseed oil during frying (approximately 1.061 mg/g), probably owing to the high content of unsaturated fatty acids in rapeseed oil and their instability. In total, 22 key flavour substances were detected. Although the flavours differed with different oils, flavour compounds including 3-(methyl sulphide) propionic aldehyde, (E,E)-2,4-sebacedienal, nonaldehyde, and 3-hydroxy-2-butanone contributed to overall flavour. PLSR analysis revealed that C18:2, 9t12t is produced with (E)-2-hexenaldehyde and nonaldehyde. (E,E)-2,4-sebacedienal levels were positively correlated with those of C18:2, 9c12t and C18:2, 9t12c. Most aliphatic aldehydes and pyrazines yield C18:3, 9t12t15c TFAs. These results indicate the characteristic flavour profile of youtiao and promote the preparation of healthy fried food.
The Determination of a Damage Model for Mudstone under Uniaxial Loading in Acidic Conditions
Authors: Cao K. , Ma L. , Wu Y. , (Sam) Spearing A. J. S. , Khan Naseer Muhammad , Xie Y.
Published: October 2020

The influence of acid solutions was investigated on the mechanical properties of mudstone. Uniaxial compression tests on mudstone samples were conducted to determine the variations of relative mass, porosity, deformation, and strength characteristics of mudstone subjected to acidic solutions with different pH values. The change of pH, relative mass, and porosity of mudstone in the process of acid solution immersion was monitored during soaking. The mechanism of hydrochemical corrosion of mudstone samples was preliminarily discussed. The damage parameter was introduced based on the porosity rate. The results show that with increased solution acidity, the peak stress and elastic modulus decreased to different levels, while the peak strain increases in the rock samples. The increased chemical damage parameters reduce the mechanical parameters and increased the deformation parameters. On the basis of the mechanical test, considering the stress-strain relationship of rock in the compaction stage, a segmented damage constitutive model of rock based on chemical damage parameters is established, and the test results are verified. The results show that the correlation coefficient between the theoretical curve and the experimental data is as high as 0.98, and the model is suitable for the analysis of chemically corroded rock under the uniaxial compression test. The results provide a reference for the analysis and design of coal-bed methane wells where the rocks frequently become acidic during the production of methane.
Artificial Intelligence-Based Classification of Chest X-Ray Images into COVID-19 and Other Infectious Diseases
Authors: Sharma Arun , Rani Sheeba , Gupta Dinesh
Published: October 2020

The ongoing pandemic of coronavirus disease 2019 (COVID-19) has led to global health and healthcare crisis, apart from the tremendous socioeconomic effects. One of the significant challenges in this crisis is to identify and monitor the COVID-19 patients quickly and efficiently to facilitate timely decisions for their treatment, monitoring, and management. Research efforts are on to develop less time-consuming methods to replace or to supplement RT-PCR-based methods. The present study is aimed at creating efficient deep learning models, trained with chest X-ray images, for rapid screening of COVID-19 patients. We used publicly available PA chest X-ray images of adult COVID-19 patients for the development of Artificial Intelligence (AI)-based classification models for COVID-19 and other major infectious diseases. To increase the dataset size and develop generalized models, we performed 25 different types of augmentations on the original images. Furthermore, we utilized the transfer learning approach for the training and testing of the classification models. The combination of two best-performing models (each trained on 286 images, rotated through 120° or 140° angle) displayed the highest prediction accuracy for normal, COVID-19, non-COVID-19, pneumonia, and tuberculosis images. AI-based classification models trained through the transfer learning approach can efficiently classify the chest X-ray images representing studied diseases. Our method is more efficient than previously published methods. It is one step ahead towards the implementation of AI-based methods for classification problems in biomedical imaging related to COVID-19.
Analytical Equations for Thermoacoustic Instability Sources and Acoustic Radiation from Reacting Turbulence
Authors: Miller S. A. E.
Published: October 2020

We seek to ascertain and understand source terms that drive thermoacoustic instability and acoustic radiation. We present a new theory based on the decomposition of the Navier-Stokes equations coupled with the mass fraction equations. A series of solutions are presented via the method of the vector Green’s function. We identify both combustion-combustion and combustion-aerodynamic interaction source terms. Both classical combustion noise theory and classical Rayleigh criterion are recovered from the presently developed more general theory. An analytical spectral prediction method is presented, and the two-point source terms are consistent with Lord Rayleigh’s instability model. Particular correlations correspond to the source terms of Lighthill, which represent the noise from turbulence and additional terms for the noise from reacting flow.
Model Predictive Control Based on Parametric Disturbance Compensation
Authors: Xu Lingliang , Chen Guiming , Li Guangshuai , Li Qiaoyang
Published: October 2020

Model predictive control (MPC) has been widely implemented in the motor because of its simple control design and good results. However, MPC relies on the permanent magnet synchronous motor (PMSM) system model. With the operation of the motor, parameter drift will occur due to temperature rise and flux saturation, resulting in model mismatch, which will seriously affect the control accuracy of the motor. This paper proposes a model predictive control based on parameter disturbance compensation that monitors system disturbances caused by motor parameter drift and performs real-time parameter disturbance compensation. And the frequency-domain method was used to analyze the convergence and filterability of the model. The Bode diagram of measurement error and input disturbance was studied when the parameters were underdamped, critically damped, and overdamped. Guidelines for parameter selection are given. Simulation results show that the proposed method has good dynamic performance, anti-interference ability, and parameter robustness, which effectively avoids the current static difference and oscillation problems caused by parameter changes.
Tumor DNA as a Cancer Biomarker through the Lens of Colorectal Neoplasia
Authors: Cohen Joshua D. , Diergaarde Brenda , Papadopoulos Nickolas , Kinzler Kenneth W. , Schoen Robert E.
Published: October 2020

Biomarkers have a wide range of applications in the clinical management of cancer, including screening and therapeutic management. Tumor DNA released from neoplastic cells has become a particularly active area of cancer biomarker development due to the critical role somatic alterations play in the pathophysiology of cancer and the ability to assess released tumor DNA in accessible clinical samples, in particular blood (i.e., liquid biopsy). Many of the early applications of tumor DNA as a biomarker were pioneered in colorectal cancer due to its well-defined genetics and common occurrence, the effectiveness of early detection, and the availability of effective therapeutic options. Herein, in the context of colorectal cancer, we describe how the intended clinical application dictates desired biomarker test performance, how features of tumor DNA provide unique challenges and opportunities for biomarker development, and conclude with specific examples of clinical application of tumor DNA as a biomarker with particular emphasis on early detection.

See all articles in this CEBP Focus section, “NCI Early Detection Research Network: Making Cancer Detection Possible.”
Repurposing of a Thromboxane Receptor Inhibitor Based on a Novel Role in Metastasis Identified by Phenome-Wide Association Study
Authors: Werfel Thomas A. , Hicks Donna J. , Rahman Bushra , Bendeman Wendy E. , Duvernay Matthew T. , Maeng Jae G. , Hamm Heidi , Lavieri Robert R. , Joly Meghan M. , Pulley Jill M. , Elion David L. , Brantley-Sieders Dana M. , Cook Rebecca S.
Published: October 2020

Although new drug discoveries are revolutionizing cancer treatments, repurposing existing drugs would accelerate the timeline and lower the cost for bringing treatments to cancer patients. Our goal was to repurpose CPI211, a potent and selective antagonist of the thromboxane A2-prostanoid receptor (TPr), a G-protein–coupled receptor that regulates coagulation, blood pressure, and cardiovascular homeostasis. To identify potential new clinical indications for CPI211, we performed a phenome-wide association study (PheWAS) of the gene encoding TPr, TBXA2R, using robust deidentified health records and matched genomic data from more than 29,000 patients. Specifically, PheWAS was used to identify clinical manifestations correlating with a TBXA2R single-nucleotide polymorphism (rs200445019), which generates a T399A substitution within TPr that enhances TPr signaling. Previous studies have correlated 200445019 with chronic venous hypertension, which was recapitulated by this PheWAS analysis. Unexpectedly, PheWAS uncovered an rs200445019 correlation with cancer metastasis across several cancer types. When tested in several mouse models of metastasis, TPr inhibition using CPI211 potently blocked spontaneous metastasis from primary tumors, without affecting tumor cell proliferation, motility, or tumor growth. Further, metastasis following intravenous tumor cell delivery was blocked in mice treated with CPI211. Interestingly, TPr signaling in vascular endothelial cells induced VE-cadherin internalization, diminished endothelial barrier function, and enhanced transendothelial migration by tumor cells, phenotypes that were decreased by CPI211. These studies provide evidence that TPr signaling promotes cancer metastasis, supporting the study of TPr inhibitors as antimetastatic agents and highlighting the use of PheWAS as an approach to accelerate drug repurposing.
Recurrent Neuroretinitis: A Unique Presentation of Behçet’s Disease in a Child
Authors: Rabina Gilad , Amarilyo Gil , Zur Dinah , Harel Liora , Habot-Wilner Zohar
Published: October 2020

We describe a case of Behçet’s disease (BD) in a young child that presented with recurrent neuroretinitis and developed retinal lesions during follow-up. A 4.5-year-old girl presented with fever of 39.5°C, erythema nodosum in her legs, bilateral knee arthritis, and perineum aphthae. On ocular examination, visual acuity was 20/25 in both eyes. Right eye examination was normal and the left eye (LE) showed mild anterior and intermediate uveitis, normal optic disc, and a macular star appearance. Laboratory workup demonstrated elevated C-reactive protein levels, a normal abdominal ultrasound, and a normal colonoscopy. The patient was diagnosed with BD. One month post initial presentation, the patient presented with visual acuity of finger counting in the LE with significant anterior uveitis, mild intermediate uveitis, and recurrent neuroretinitis. Under treatment of IV methylprednisolone, oral betamethasone, infliximab, and colchicine, a complete systemic remission was noticed, and uveitis became quiescent. On last examination, 4.5 years post first presentation, visual acuity was 20/25 in both eyes and the LE demonstrated a remnant of a juxtafoveal retinal scar. To the best of our knowledge, this is the first case of neuroretinitis presenting as a manifestation of pediatric BD. Ophthalmologists should be aware of these unique manifestations of ocular BD.
Exploding Head Syndrome: A Case Series of Underdiagnosed Hypnic Parasomnia
Authors: Pirzada Abdul Rouf , Almeneessier Aljohara S. , BaHammam Ahmed Salem
Published: October 2020

Exploding head syndrome (EHS) is an under-recognized parasomnia characterized by a complaint of sudden loud noise or a sense of explosion in the head that usually occurs at sleep onset. This paper is a report of 6 patients diagnosed with EHS through a structured clinical interview and video-polysomnography (vPSG) recordings. We also reviewed the available literature that addressed the presentation and clinical and PSG characteristics of EHS. The case series included 4 men and 2 women of a mean age of 44.2 years (between 13 and 77 years). Their episodes were variable in expression, between a sudden firecracker-like explosion to a gun-shot sound, mostly as if happening inside the head. EHS is always associated with distress but never with pain. Five out of 6 patients had other sleep-related problems with a close relationship of EHS symptoms to comorbid sleep disorder manifestations and exacerbations. The vPSG recordings of 5 patients were unremarkable. An attack of EHS was documented in 1 patient, arising during stage N2 of sleep. Three patients responded well to reassurance and treatment for the comorbid sleep disorder. The other 3 patients responded well to amitriptyline (10–50 mg). EHS is a well-characterized, underrecognized hypnic parasomnia with a benign course. Amitriptyline seems to be effective in persistent cases.
Amoxycillin-Clavulanic Acid-Induced Esophageal Ulcer: An Unusual Cause
Authors: Kaewdech Apichat , Pattarapuntakul Tanawat , Sripongpun Pimsiri
Published: October 2020

Pill-induced esophagitis or esophageal ulcers are considered when patients have retrosternal chest pain or odynophagia following the ingestion of suspicious medications. Various drugs have been reported to induce esophageal ulcers. However, amoxycillin-clavulanic acid-induced esophagitis or esophageal ulcer has not been reported in literature. Hence, we report the case of a 30-year-old Thai male who presented with acute, severe odynophagia and retrosternal chest pain. He had a history of taking amoxycillin-clavulanic acid for 12 days. An esophagogastroduodenoscopy was performed and revealed geographic clean-based ulcers, with a kissing-ulcer appearance at the level of the mid-esophagus. A biopsy was taken and revealed inflamed granulation tissue and an ulcer with neither infection nor malignancy. Thus, the diagnosis of an amoxycillin-clavulanic acid-induced esophageal ulcer was made according to the clinicopathologic report.
Assessing the Validity of Echocardiographic Criteria for Left Ventricular Diastolic Dysfunction in Patients with Pulmonary Hypertension
Authors: Allison John David , Zehner Carl , Jia Xiaoming , Hamzeh Ihab Rafic , Alam Mahboob , Nair Ajith , Birnbaum Yochai
Published: October 2020

Background: In patients with pulmonary hypertension (PHT), the assessment of left ventricular (LV) diastolic function by echocardiography may not be reliable. PHT can affect Doppler parameters of LV diastolic function such as mitral inflow velocities and mitral annular velocities. The current guidelines for the assessment of LV diastolic function do not recommend specific adjustments for patients with PHT. Methods: We analyzed 36 patients from the PHT clinic that had an echocardiogram and right heart catheterization performed within 6 months of each other. Early mitral inflow velocity (E), lateral mitral annular velocity (lateral e’), septal mitral annular velocity (septal e’), tricuspid free wall annular velocity (RV e’) were measured and compared to the invasively measured intracardiac pressures including pulmonary capillary wedge pressure (PCWP), mean pulmonary artery pressure, and right ventricular end-diastolic pressure. Results: Among patients with PHT, the specificity of the septal e’ for LV diastolic dysfunction was 0.19, and the positive predictive value was 0.13 (lower than the lateral e’ or E/average e’). By receiver-operating characteristic curve analysis, the area under the curve (AUC) of lateral and septal e’ was just 0.64 (p = 0.9) and 0.53 (p = 0.6), respectively, while the AUC of average E/e’ was 0.94 (p < 0.001). The septal e’ was paradoxically lower at 6.5 ± 1.9 cm/s for normal PCWP compared to 6.9 ± 1.7 cm/s for elevated PCWP (p = 0.04). 81 versus 40% (p = 0.017) of patients with normal versus elevated PCWP had an abnormal septal e’ <7 cm/s. By linear regression, there was no correlation between the Doppler parameters of LV diastolic function and the PCWP. Conclusion: Our study suggests E/average e’ may be the only reliable tissue Doppler parameter of LV diastolic dysfunction in patients with PHT, and that septal e’ is paradoxically decreased in patients with PHT and normal left-sided filling pressures.
Cornea Procurement and Processing up to 72 Hours: No Risk for Cornea Transplant Quality
Authors: Hofmann Nicola , Wittmershaus Ilka , Salz Anna-Katharina , Börgel Martin
Published: October 2020

Background: The realization of tissue donations is bound to a tight timeframe. Depending on the type of tissue, time limits are specified within which the donation must be procured and processed. Otherwise, there is a risk of tissue quality loss with increasing time intervals from cardiovascular arrest. According to the European Directorate for the Quality of Medicines and HealthCare (EDQM) guide, cornea must be procured and processed within 72 h after death. The question arises whether this time interval has an influence on the quality of transplanted tissues and how it affects the accomplishment of tissue donations. Methods: In order to obtain information on this, the numbers of tissue donations in the network of the German Society for Tissue Transplantation (DGFG) were evaluated as a function of the death to retrieval time (DRT) as well as the death to preservation time (DPT). For this purpose, 21,454 database entries of cornea donations made in the period from 2014 to 2018 were included. Results: The results show that nearly 50% of donations realized in the DGFG network could be processed only 48 h or later after cardiovascular death due to the opt-in regulation in Germany. For these donations, there seems to be a higher discard rate compared to donations taken earlier. Nevertheless, there is a transplantation rate for these grafts of more than 65%, which is comparable to average transplantation rates stated in the literature. Conclusion: All corneas finally selected for transplantation must meet the specified quality parameters. Since this naturally also applies to transplants that could only be procured at later time points, it can be concluded that DPT up to 72 h for corneal tissue is adequate and has no influence on the quality of corneas that are ultimately transplanted.
Laparoscopic versus Open Hepatectomy for Hepatocellular Carcinoma in Elderly Patients: A Single-Institutional Propensity Score Matching Comparison
Authors: Dumronggittigule Wethit , Han Ho-Seong , Ahn Soyeon , Yoon Yoo-Seok , Cho Jai Young , Choi YoungRok
Published: October 2020

Background: The incidence of hepatocellular carcinoma (HCC) in elderly patients is increasing worldwide. Although open hepatectomy (OH) yields acceptable outcomes, high morbidity rate is concerned. Laparoscopic hepatectomy (LH) has evolved to improve perioperative outcomes. However, comparative study between both techniques for elderly patients with HCC is scarce. Objective: This study aimed to compare outcomes between LH and OH specifically. Methods: HCC patients aged ≥70 years after hepatectomy (2003–2018) were included. The propensity score matching (PSM) and comparative analyses between groups were performed. Results: After PSM, there were 41 patients in each group with similar demographics, radiographic tumor characteristics, cirrhotic status, and extent of resection. The LH group had a shorter hospital stay (7 vs. 11 days, p = 0.002) compared with the OH group. The completeness of resection and complication rates were not statistically different between groups. The 5-year overall survival and recurrence-free survival rates were 86.7 and 43.4% in the LH group and 62.2 and 30.8% in the OH group (p = 0.221 and 0.500). Conclusion: Our study confirmed the operative and oncological safety of LH in elderly HCC patients with improved perioperative outcomes compared with OH.
Sudden Cardiac Death in Haemodialysis Patients under Hydroxychloroquine Treatment for COVID-19: A Report of Two Cases
Authors: Murt Ahmet , Dincer Mevlut Tamer , Karaca Cebrail
Published: October 2020

Hydroxychloroquine (HQ) has been used for the treatment of novel coronavirus disease (COVID-19) even though there is no clear evidence for its effectiveness yet. In contrary, HQ has major side effects like QTc prolongation and subsequent development of ventricular arrhythmias. Such side effects may possess additional risks on end-stage renal disease (ESRD) patients who have higher cardiovascular risks than general population. We herein present 2 cases of sudden cardiac death in 2 ESRD patients with COVID-19 for whom a treatment regimen including HQ was preferred. Both patients were clinically stable at the time of arrest. Death could not be attributed to worsening of the COVID-19 since the patients’ clinical picture and laboratory values were improving. The cardiac events coincided with the end of routine haemodialysis sessions of both patients. Electrocardiography controls upon admission and on the 24 and 48 h of treatment showed normal QTc intervals. Potential risks contributing to sudden cardiac death during HQ treatment of ESRD patients are discussed.
Adaptive Fuzzy Gain of Power System Stabilizer to Improve the Global Stability
Authors: Mekhanet Mohammed , Mokrani Lakhdar , Ameur Aissa , Attia Yacine
Published: October 2020

The lead-lag power system stabilizer has several parameters to be optimized.In fact, the number of these latter increases with the number of generators constituting the multi-machine system.In this work, we propose anew approach of an adaptive and robust PSS; it achieves encouraging results by adjusting the gain using fuzzy logic and in the same time we use the same PSSs for each machine. In the first place, we could check that the gain is among the most critical parameters of the lead lag PSS. The parameters are globally optimized by the genetic algorithm, after that an expertise on the speed and the gain variations allow the value prediction according to the velocity deviation. To validate our results, a robustness test was made on a multimachine system IEEE (3 machines 9 bus), for different loads and the results showed good performance and robustness of the presented PSS.
Data Flow in Wireless Sensor Network Protocol Stack by using Bellman-Ford Routing Algorithm
Authors: Kumar Saini Rakesh , Ritika Ritika , Vijay Sandip
Published: October 2020

Wireless sensor network consists various sensor nodes that are used to monitor any target area like forest fire detection by our army person and monitoring any industrial activity by industry manager. Wireless sensor networks have been deployed in several cities to monitor the concentration of dangerous gases for citizens. In wireless sensor network when sensor nodes communicate from each other then routing protocol are used for communication between protocol layers. Wireless sensor network protocol stack consist five layers such as Application layer, Transport layer, Network layer, MAC Layer, Physical layer. In this paper we study and analysis Bellman-Ford routing algorithm and check the flow of data between these protocol layers. For simulation purpose we are using Qualnet 5.0.2 simulator tool.
Analysis, Design and Optimization of Multilayer Antenna Using Wave Concept Iterative Process
Authors: Houda Amri
Published: October 2020

The wave concept iterative process is a procedure used for analyses a planar circuits This method consists in generating a recursive relationship between a wave source and reflected waves from the discontinuity plane which is divided into cells. A high computational speed has been achieved by using Fast Modal Transform (FMT). In this paper we study a patch antenna and multilayer circuits, to determine the electromagnetic characteristics of these structures.
Robotic Leg Design to Analysis the Human Leg Swing from Motion Capture
Authors: Yunardi Riky Tri , Firdaus Aji Akbar , Agustin Eva Inaiyah
Published: October 2020

In this paper presented the prototype of robotic leg has been designed, constructed and controlled. These prototype are designed from a geometric of human leg model with three joints moving in 2D plane. Robot has three degree of freedom using DC servo motor as a joint actuators: hip, knee and ankle. The mechanical leg constructed using aluminum alloy and acrylic material. The control movement of this system is based on motion capture data stored on a personal computer. The motions are recorded with a camera by use of a marker-based to track movement of human leg. Propose of this paper is design of robotic leg to present the analysis of motion of the human leg swing and to testing the system ability to create the movement from motion capture. The results of this study show that the design of robotic leg was capable for practical use of the human leg motion analysis. The accuracy of orientation angles of joints shows the average error on hip is 1.46º, knee is 1.66º, and ankle is 0.46º. In this research suggesting that the construction of mechanic is an important role in the stabilization of the movement sequence.
Development of E-learning Software Based Multiplatform Components
Authors: Salamah Irma , Ganiardi M. Aris
Published: October 2020

E-learning software is a product of information and communication technology used to help dynamic and flexible learning process between teacher and student. The software technology was first used in the development of e-learning software in the form of web applications. The advantages of this technology because of the ease in the development, installation, and distribution of data. Along with advances in mobile/wireless electronics technology, e-learning software is adapted to this technology known as mobile learning. The ability of this electronic device is the same as a single computer even though it is simpler than a single computer. The problem that arises when e-learning software operates on multiple platforms is that computer programs are made repeatedly depending on the platform being used. This situation will obviously affect the quality of e-learning software. To overcome these problems, in this study developed component-based software that is a modern paradigm for software development that produces reusable software components, high quality, and cost-effective. In software development, software components will be assembled in the software in need. The result of this research is high quality e-learning software based multiplatform component.
Throughput and Handover Latency Evaluation for Multicast Proxy Mobile IPV6
Authors: Hashim Aisha , Hafizah Mohd Aman Azana , Adibah Mohd Ramli Huda
Published: October 2020

The objective of this paper is to present performance analysis of a new enhanced mobile multicast network mobility management scheme. The initial developed network mobility management called Proxy Mobile IPv6 (PMIPv6) is based on unicast network support. This paper enabled multicast support in network mobility management and named it as MPMIPv6. Additionally this enhancement also provides better network performance with the new context transfer operations and fast reroute operations. In brief, this paper also describes other current mobile multicast schemes. The new scheme is evaluated using mathematical analysis and NS3.19 simulator. Theoretically this scheme reduces service recovery time, total signalling cost, handover latency, and packet loss for multicast communication. However for this paper, the analysed parameters are throughput and handover latency. Both mathematical and simulation results exhibit better network performance   for multicast environment compared to the standard benchmark scheme.
Content Cytotoxicity Studies of Colorectal Carcinoma Cells Using Printed Impedance Sensors
Authors: Nurashikin Nordin Anis , Ibrahim Irmanisha , Fairuzabadi Mohd Mansor Ahmad , Zuhanis Has-Yun Hashim Yumi , Voiculescu Ioana
Published: October 2020

Monitoring the effectiveness of drugs on cancer cells is crucial for chemotherapeutics studies. In-vitro cell-based biosensors can be used as an alternative for characteristic studies of cells’ response to drugs. Cell-based sensors provide real-time measurements and require smaller sample volumes compared to conventional T-flask measurement methods. This paper presents a biosensor that detects in real-time, impedance variations of human colon cancer, HCT-116 cells when treated with anti-cancer agent, 5-Fluorouracil (5-FU). Two different extracellular matrix (ECM); polyaniline and gelatin were tested and evaluated in terms of attachment quality. Polyaniline was found to provide the best attachment for HCT-116 cells and was used for cytotoxicity studies. Cytokinetic behavior indicated that 5-FU inhibited HCT-116 cells at IC50 of 6.8 µg/mL. Trypan blue exclusion method for testing cell viability was used to validate the impedance measurements, where the cancer cell concentrations were reduced to ~35% when treated with 2.5 µg/mL, and 50% when treated with 6.8 µg/mL. The results generated by the microfabricated impedance biosensor are comparable to the Trypan blue method since both gave similar cell growth trend. It can be concluded that the impedance biosensor has potential to be used as an alternative method in drug testing applications.
System on Chip Based RTC in Power Electronics
Authors: Dorothy R. , T. Sasilatha
Published: October 2020

Current control systems and emulation systems (Hardware-in-the-Loop, HIL or Processor-in-the-Loop, PIL) for high-end power-electronic applications often consist of numerous components and interlinking busses: a micro controller for communication and high level control, a DSP for real-time control, an FPGA section for fast parallel actions and data acquisition, multiport RAM structures or bus systems as interconnecting structure. System-on-Chip (SoC) combines many of these functions on a single die. This gives the advantage of space reduction combined with cost reduction and very fast internal communication. Such systems become very relevant for research and also for industrial applications. The SoC used here as an example combines a Dual-Core ARM 9 hard processor system (HPS) and an FPGA, including fast interlinks between these components. SoC systems require careful software and firmware concepts to provide real-time control and emulation capability. This paper demonstrates an optimal way to use the resources of the SoC and discusses challenges caused by the internal structure of SoC. The key idea is to use asymmetric multiprocessing: One core uses a bare-metal operating system for hard real time. The other core runs a “real-time” Linux for service functions and communication. The FPGA is used for flexible process-oriented interfaces (A/D, D/A, switching signals), quasi-hard-wired protection and the precise timing of the real-time control cycle. This way of implementation is generally known and sometimes even suggested–but to the knowledge of the author’s seldomly implemented and documented in the context of demanding real-time control or emulation. The paper details the way of implementation, including process interfaces, and discusses the advantages and disadvantages of the chosen concept. Measurement results demonstrate the properties of the solution.
Defense-through-Deception Network Security Model: Securing University Campus Network from DOS/DDOS Attack
Authors: A. Naagas M. , L. Mique Jr E. , D. Palaoag T. , S. Dela Cruz J.
Published: October 2020

Denial of Service (DOS) and (DDOS) Distributed Denial of Service attacks have become a major security threat to university campus network security since most of the students and teachers prepare online services such as enrolment, grading system, library etc. Therefore, the issue of network security has become a priority to university campus network management. Using online services in university network can be easily compromised. However, traditional security mechanisms approach such as Defense-In-Depth (DID) Model is outdated in today’s complex network and DID Model has been used as a primary cybersecurity defense model in the university campus network today. However, university administration should realize that Defense-In-Depth (DID) are playing an increasingly limited role in DOS/DDoS protection and this paper brings this fact to light. This paper presents that the Defense-In-Depth (DID) is not capable of defending complex and volatile DOS/DDOS attacks effectively. The test results were presented in this study in order to support our claim. The researchers established a Defense-In-Depth (DID) Network model at the Central Luzon State University and penetrated the Network System using DOS/DDOS attack to simulate the real network scenario. This paper also presents the new approach Defense-through-Deception network security model that improves the traditional passive protection by applying deception techniques to them that give insights into the limitations posed by the Defense-In-Depth (DID) Model. Furthermore, this model is designed to prevent an attacker who has already entered the network from doing damage.
Analysis on the Performance of Technology Companies with Z-score Model
Authors: Weng Hoe Lam , Hong Beng Yeoh , Weng Siew Lam , Jia Wai Chen
Published: October 2020

Local technology sector plays a significant role in information and communication technology (ICT) based innovations and applications which enhance organizational performance as well as national economic growth and labor productivity. In this paper, financial performance of the listed Malaysia companies in technology sector is analyzed and evaluated. Altman’s Z-score model is proposed due to its robustness in determining companies’ financial distress level using five financial ratios as variables. The computed Z-score values classify the financial status of the companies into distress, grey and safe zones. This study investigates the financial data of 23 listed technology-based companies in the Main Market of Bursa Malaysia over the period of 2013 to 2017. The findings reveal that the percentage of safe zone companies increase throughout the five years whereas distress zone companies decline. It is concluded that financial ratio for market value of equity to total liabilities is the dominant factor that directly influences the level of financial distress among these technology-based companies in Malaysia. These research outcomes provide an insight to investors or policy makers to develop future planning in order to avoid financial failure in local technology sector.
Microwave Planar Sensor for Determination of the Permittivity of Dielectric Material
Authors: Khairy Ismail Mohd , Zakaria Zahriladha , Hassan Nornikman , Weng Yik Sam , Mawardy Abdullah Mohd
Published: October 2020

This paper proposed a single port rectangular microwave resonator sensor. This sensor operates at the resonance frequency of 4GHz. The sensor consists of micro-strip transmission line and applied the enhancement method. The enhancement method is able to improve the return loss of the sensor, respectively. Plus, the proposed sensor is designed and fabricated on Roger 5880 substrate. Based on the results, the percentage of error for the proposed rectangular sensor is 0.2% to 8%. The Q-factor of the sensor is 174.
Mobile Business Intelligence Acceptance Model for Organisational Decision Making
Authors: Yee Fang Lim , Firdaus Mohd Azmi Nurulhuda , Yahya Yazriwati , Sarkan Haslina , Nur Amir Sjarif Nilam , Chuprat Suriayati
Published: October 2020

Mobile Business Intelligence (BI) is the ability to access BI-related data such as key performance indicators (KPIs), business metric and dashboard through mobile device. Mobile BI addresses the use-case of remote or mobile workers that need on-demand access to business-critical data. User acceptance on mobile BI is an essential in order to identify which factors influence the user acceptance of mobile BI application. Research on mobile BI acceptance model on organizational decision-making is limited due to the novelty of mobile BI as newly emerged innovation. In order to answer gap of the adoption of mobile BI in organizational decision-making, this paper reviews the existing works on mobile BI Acceptance Model for organizational decision-making. Two user acceptance models which are Technology Acceptance Model and Technology Acceptance Model for Mobile Services will be review. Realizing the essential of strategic organizational decision-making in determining success of organizations, the potential of mobile BI in decision-making need to be explore. Since mobile BI still in its infancy, there is a need to study user acceptance and usage behavior on mobile BI in organizational decision-making. There is still opportunity for further investigate the impact of mobile BI on organizational decision-making.
Distribution Network Reconfiguration Using Binary Particle Swarm Optimization to Minimize Losses and Decrease Voltage Stability Index
Authors: Akbar Firdaus Aji , Penangsang Ontoseno , Soeprijanto Adi , Fajar U.P. Dimas
Published: October 2020

Power losses and voltage drop are existing problems in radial distribution networks. This power losses and voltage drop affect the voltage stability level. Reconfiguring the network is a form of approach to improve the quality of electrical power. The network reconfiguration aims to minimize power losses and voltage drop as well as decreasing the Voltage Stability Index (VSI). In this research, network reconfiguration uses binary particle swarm optimization algorithm and Bus Injection to Branch Current-Branch Current to Bus Voltage (BIBC-BCBV) method to analyze the radial system power flow. This scheme was tested on the 33-bus IEEE radial distribution system 12.66 kV. The simulation results show that before reconfiguration, the active power loss is 202.7126 kW and the VSI is 0.20012. After reconfiguration, the active power loss and VSI decreased to 139.5697 kW and 0.14662, respectively. It has decreased the power loss for 31.3136% significantly while the VSI value is closer to zero.
A hardware system with ARM-based data processing for nano satellites
Authors: Stacul Adrián , Pastafiglia Daniel , Di Giovanni Ariel , Morales Martín , Saluzzi Sergio , García Gerardo , Gadea Agustín , Puga Ramiro
Published: October 2020

The Institute of Scientiﬁc and Technical Research for Defense in Argentina (Instituto de Investigaciones Cientíﬁcas y Técnicas para la Defensa - CITEDEF) is developing a processing hardware module based on a ARM Cortex M4 processor from STMicroelectronics. The microcontroller (MCU) has the capacity to run at a maximum clock frequency of 180 MHz, integrates a Floating Point Unit (FPU). An 8MB SDRAM was included for dynamic data allocation. This hardware will host and process the algorithms to calculate and determine the nanosatellite’s attitude. The module is intended to be Cubesat compatible, possess a ﬂexible design, handles various inertial sensors and can manage backups on microSD memory cards with sizes up to 32GB.
Data ecryption based on multi-order FrFT, and FPGA implementation of DES algorith
Authors: Rabie A. , El Shafie Kh. , Hammuoda A. , Rohiem M.
Published: October 2020

Cryptography techniques need some algorithms for encryption of data. Most of available encryption techniques are used for textual data; a few of encryption methods are used for multimedia data; However, This Algorithms that are used for textual data may not be inefficient for multimedia, because it is size is greater than the text. Therefore, Cryptosystems need to find and develop a new encryption schemes for such data. The most popular symmetric key algorithms are Data Encryption Standard (DES). However, DES is may be not suitable for multimedia because it consumes times. Encryption and decryption of these data require different methods. In this paper a method for encryption/decryption data by using the nature of FrFT in signals analysis, based on multi-order Fractional Fourier Transform has been introduced. The security of the method used in the encryption work was taken into account to identify the different indicators to measure the security of the encryption Techniques. These indicators are: sensitivity proposed Techniques for the key, the complexity of the processes, and statistical analysis. The key is formed by combination of order of Fractional Fourier Transform. The encrypted data is obtained by the summation of different orders. Numerical simulation results are given to demonstrate this proposed method.
A system verilog approach for verification of memory controller
Authors: K B Sowmya , P Gagana
Published: October 2020

Memory performance has become the major bottleneck to improve the overall performance of the computer system. By using memory controller, there is effective control of data between processor and memory. In this paper, a memory controller for interfacing Synchronous Static Random Access Memory (SSRAM), Synchronous Dynamic Random Access Memory (SDRAM), Read Only Memory (ROM) and FLASH which is Electrically Erasable Programmable Read-Only Memory is designed and a coverage driven Constraint random verification environment is built for the designed memory controller. Verification plays an important role in any design flow as it is done before silicon development. It is done at time of product development for quality checking and bug fixing in design.
Platelet Extracellular Vesicles
Authors: Puhm Florian , Boilard Eric , Machlus Kellie R.
Published: October 2020

Extracellular vesicles (EVs) are a means of cell-to-cell communication and can facilitate the exchange of a broad array of molecules between adjacent or distant cells. Platelets are anucleate cells derived from megakaryocytes and are primarily known for their role in maintaining hemostasis and vascular integrity. Upon activation by a variety of agonists, platelets readily generate EVs, which were initially identified as procoagulant particles. However, as both platelets and their EVs are abundant in blood, the role of platelet EVs in hemostasis may be redundant. Moreover, findings have challenged the significance of platelet-derived EVs in coagulation. Looking beyond hemostasis, platelet EV cargo is incredibly diverse and can include lipids, proteins, nucleic acids, and organelles involved in numerous other biological processes. Furthermore, while platelets cannot cross tissue barriers, their EVs can enter lymph, bone marrow, and synovial fluid. This allows for the transfer of platelet-derived content to cellular recipients and organs inaccessible to platelets. This review highlights the importance of platelet-derived EVs in physiological and pathological conditions beyond hemostasis.