bluuebunny/crossref_metadata_2025 huggingface dataset:
Dietary intakes of berries and flavonoids in relation to cognitive decline
Authors: Devore Elizabeth E. , Kang Jae Hee , Breteler Monique M. B. , Grodstein Francine
Published: April 2012

Objective:

Berries are high in flavonoids, especially anthocyanidins, and improve cognition in experimental studies. We prospectively evaluated whether greater long‐term intakes of berries and flavonoids are associated with slower rates of cognitive decline in older women.

Methods:

Beginning in 1980, a semiquantitative food frequency questionnaire was administered every 4 years to Nurses' Health Study participants. In 1995–2001, we began measuring cognitive function in 16,010 participants, aged ≥70 years; follow‐up assessments were conducted twice, at 2‐year intervals. To ascertain long‐term diet, we averaged dietary variables from 1980 through the initial cognitive interview. Using multivariate‐adjusted, mixed linear regression, we estimated mean differences in slopes of cognitive decline by long‐term berry and flavonoid intakes.

Results:

Greater intakes of blueberries and strawberries were associated with slower rates of cognitive decline (eg, for a global score averaging all 6 cognitive tests, for blueberries: p‐trend = 0.014 and mean difference = 0.04, 95% confidence interval [CI] = 0.01–0.07, comparing extreme categories of intake; for strawberries: p‐trend = 0.022 and mean difference = 0.03, 95% CI = 0.00–0.06, comparing extreme categories of intake), after adjusting for multiple potential confounders. These effect estimates were equivalent to those we found for approximately 1.5 to 2.5 years of age in our cohort, indicating that berry intake appears to delay cognitive aging by up to 2.5 years. Additionally, in further supporting evidence, greater intakes of anthocyanidins and total flavonoids were associated with slower rates of cognitive decline (p‐trends = 0.015 and 0.053, respectively, for the global score).

Interpretation:

Higher intake of flavonoids, particularly from berries, appears to reduce rates of cognitive decline in older adults. ANN NEUROL 2012
A common polymorphism near PER1 and the timing of human behavioral rhythms
Authors: Lim Andrew S. P. , Chang Anne‐Marie , Shulman Joshua M. , Raj Towfique , Chibnik Lori B. , Cain Sean W. , Rothamel Katherine , Benoist Christophe , Myers Amanda J. , Czeisler Charles A. , Buchman Aron S. , Bennett David A. , Duffy Jeanne F. , Saper Clifford B. , De Jager Philip L.
Published: April 2012

Objective:

Circadian rhythms influence the timing of behavior, neurological diseases, and even death. Rare mutations in homologs of evolutionarily conserved clock genes are found in select pedigrees with extreme sleep timing, and there is suggestive evidence that certain common polymorphisms may be associated with self‐reported day/night preference. However, no common polymorphism has been associated with the timing of directly observed human behavioral rhythms or other physiological markers of circadian timing at the population level.

Methods:

We performed a candidate gene association study with replication, evaluating associations between polymorphisms in homologs of evolutionarily conserved clock genes and the timing of behavioral rhythms measured by actigraphy. For validated polymorphisms, we evaluated associations with transcript expression and time of death in additional cohorts.

Results:

rs7221412, a common polymorphism near period homolog 1 (PER1), was associated with the timing of activity rhythms in both the discovery and replication cohorts (joint p = 2.1 × 10−7). Mean activity timing was delayed by 67 minutes in rs7221412GG versus rs7221412AA homozygotes. rs7221412 also showed a suggestive time‐dependent relationship with both cerebral cortex (p = 0.05) and CD14+CD16− monocyte (p = 0.02) PER1 expression and an interesting association with time of death (p = 0.015) in which rs7221412GG individuals had a mean time of death nearly 7 hours later than rs7221412AA/AG.

Interpretation:

A common polymorphism near PER1 is associated with the timing of human behavioral rhythms, and shows evidence of association with time of death. This may be mediated by differential PER1 expression. These results may facilitate individualized scheduling of shift work, medical treatments, or monitoring of vulnerable patient populations. ANN NEUROL 2012;72:324–334.
Parametric studies on the synthesis of amidoximated adsorbent resins
Authors: Rafiee R. , Babalou A. A. , Nilchi A. , Razavi Aghjeh M. K.
Published: April 2012

The main goal of this study was to obtain acrylonitrile (AN)‐divinylbenzene (DVB) copolymer beads that can serve as the matrix for preparation of amidoxime resins. AN‐DVB amidoxime resin was synthesized via suspension polymerization and the effect of different parameters such as the speed of stirrer, the amounts of suspending agent, hydrophilic agent, diluent agent, and initiator on its properties was investigated by fractional factorial (Taguchi) experimental design method. This method gives much‐reduced variance for the experiments with optimum control parameters setting and provides a set of minimum experiments compared to the conventional methods. The results showed that the most effective parameters on the amidoximation of resins were hydrophilic agent content, speed of stirrer, and the amount of suspending agent, respectively. Furthermore, anion‐exchange capacity of the amidoxime resins was utilized as a criterion for the evaluation of amidoxime adsorbent groups and the adsorption potential of the synthesized resins was determined by cation‐exchange capacity. The amount of methylacrylate as a hydrophilic agent had the most significant effect on the ion‐exchange capacity of the final product. Swelling ratio was also measured to evaluate the adsorption capacity of the synthesized resin. The results showed that the amounts of hydrophilic and diluent agents had significant effects on swelling ratio of resin. Finally, cation‐exchange capacity and swelling ratio of amidoxime resin were changed greatly because of alkaline treatment, but it had no significant effect on the anion‐exchange capacity of the synthesized resin. © 2012 Wiley Periodicals, Inc. J Appl Polym Sci, 2012
The influence of solvent type and polymer concentration on the physical properties of solid state polymerized PA66 nanofiber yarn
Authors: Sanatgar Razieh Hashemi , Borhani Sedigheh , Ravandi Seyed Abdolkarim Hosseini , Gharehaghaji Ali Akbar
Published: April 2012

We investigated the effects of two different solvent types and three solution concentrations on the electrospinning of solid state polymerized polyamide 66 (SSP PA66) nanofiber yarns. Nanofiber yarns were electrospun from SSP PA66 solutions in formic acid and formic acid/chloroform (3/1), using two oppositely metallic spinnerets system. Scanning electron microscopy (SEM) and X‐ray diffraction (XRD) were employed to characterize the morphology and properties of the nanofibrous yarns. Experimental results show that adding chloroform to formic acid as a binary solvent increases viscosity of polymer solution and the nanofibers diameter significantly. XRD patterns reveal that the presence of chloroform affects the crystallinity and the mechanical properties of the produced nanofibrous yarns. PA66 nanofiber yarn from 10 wt % formic acid/chloroform (3/1) solution was successfully electrospun with strength and modulus of 120.16 MPa and 1216.27 MPa respectively. It is also shown that the solution concentration has a significant effect on the modulus of the nanofibers yarns. © 2012 Wiley Periodicals, Inc. J Appl Polym Sci, 2012
Revisiting two sympatric European seahorse species: apparent decline in the absence of exploitation
Authors: Caldwell I.R. , Vincent A.C.J.
Published: April 2012

Seahorses are marine fish with several life history characteristics hypothesized to make them resilient but are of conservation concern because of their international trade and habitat loss.

Surveys of two unexploited European seahorse species (Hippocampus guttulatus and Hippocampus hippocampus) in Ria Formosa lagoon, Portugal, were repeated seven years after their populations in the lagoon were found to be among the densest in the world.

Population densities of both species declined significantly between 2001/2002 and 2008/2009 surveys (94% and 73% for H. guttulatus and H. hippocampus respectively). H. guttulatus declines were not associated with any environmental changes measured (i.e. percentage live benthic habitat cover, depth, temperature, water current speed, horizontal visibility). H. hippocampus declined more where current speed had decreased.

At the low densities found in 2008/2009, occurrence for both species was best predicted by depth: seahorses were found in deeper locations throughout the lagoon. Other important predictors were temperature for H. guttulatus (found at sites warmer than average) and current speed for H. hippocampus (found in locations with faster currents).

The large declines in seahorse densities made it difficult to compare results over time. Presence–absence and abundance modelling at multiple scales can help to ensure that data are comparable even when populations fluctuate drastically.

Copyright © 2012 John Wiley & Sons, Ltd.
Impacts of artificial structures on the freshwater pearl mussel Margaritifera margaritifera in the River Dee, Scotland
Authors: Cooksley Susan L. , Brewer Mark J. , Donnelly David , Spezia Luigi , Tree Angus
Published: April 2012

Freshwater pearl mussels (Margaritifera margaritifera) in the River Dee (north‐east Scotland) are in decline, and now occur at low densities with poor recruitment levels. The population's deterioration has been attributed to reduced water quality, degraded river‐bed habitat and pearl fishing but the specific importance of each of these impacts has not previously been investigated.

This study focused on the impacts of artificial structures on the River Dee's freshwater pearl mussel population. Natural hydromorphological features were also included in the analysis. Relationships between the spatial distribution of the freshwater pearl mussel population and 31 explanatory variables were investigated using logistic regression. Three different model selection strategies were compared and contrasted.

An absence of freshwater pearl mussels was found to be significantly associated with the following factors: (1) presence of bank protection; (2) proximity of the nearest upstream bridge; (3) presence of a wastewater treatment works; (4) number of upstream tributaries; (5) proximity of the nearest upstream tributary; and (6) presence of sediment deposition.

The results strongly suggest that artificial structures on the main stem of the River Dee have contributed to the decline of its freshwater pearl mussel population. Hypotheses are proposed for the causal relationships involved. Requirements for further exploratory analyses, model testing, and experimentation are discussed.

This work opens a new line of investigation into the causes of the decline of freshwater pearl mussel populations, providing formal support at a catchment scale for an impact previously identified only on a site‐by‐site basis.

Copyright © 2012 John Wiley & Sons, Ltd.
The translucent cadaver: An evaluation of the use of full body digital x‐ray images and drawings in surface anatomy education
Authors: Kotzé Sanet Henriët , Mole Calvin Gerald , Greyling Linda Magdalena
Published: April 2012

It has been noted by staff at the Faculty of Health Sciences, Stellenbosch University that medical students neglect the study of surface anatomy during dissection. This study reports on the novel use of Lodox® Statscan® images in anatomical education, particularly the teaching of surface anatomy. Full body digital X‐ray images (Lodox Statscan) of each cadaver (n = 40) were provided to second year medical students. During dissection students were asked to visualize landmarks, organs, and structures on the digital X‐ray and their cadaver, as well as palpate these landmarks and structures on themselves, their colleagues, and the cadaver. To stimulate student engagement with surface anatomy, dissection groups were required to draw both the normal and actual position of organs on a laminated image provided. The accuracy of the drawings was subsequently assessed and students were further assessed by means of practical identification tests. In addition, students were asked to complete an anonymous questionnaire. A response rate of 79% was obtained for the student questionnaire. From the questionnaire it was gathered that students found the digital X‐ray images beneficial for viewing most systems' organs, except for the pelvic organs. Although it appears that students still struggle with the study of surface anatomy, most students believed that the digital X‐rays were beneficial to their studies and supported their continued use in the future. Anat Sci Educ. © 2012 American Association of Anatomists.
High‐yield export of a native heterologous protein to the periplasm by the tat translocation pathway in Escherichia coli
Authors: Matos Cristina F.R.O. , Branston Steven D. , Albiniak Anna , Dhanoya Arjun , Freedman Robert B. , Keshavarz‐Moore Eli , Robinson Colin
Published: April 2012

Numerous high‐value recombinant proteins that are produced in bacteria are exported to the periplasm as this approach offers relatively easy downstream processing and purification. Most recombinant proteins are exported by the Sec pathway, which transports them across the plasma membrane in an unfolded state. The twin‐arginine translocation (Tat) system operates in parallel with the Sec pathway but transports substrate proteins in a folded state; it therefore has potential to export proteins that are difficult to produce using the Sec pathway. In this study, we have produced a heterologous protein (green fluorescent protein; GFP) in Escherichia coli and have used batch and fed‐batch fermentation systems to test the ability of the newly engineered Tat system to export this protein into the periplasm under industrial‐type production conditions. GFP cannot be exported by the Sec pathway in an active form. We first tested the ability of five different Tat signal peptides to export GFP, and showed that the TorA signal peptide directed most efficient export. Under batch fermentation conditions, it was found that TorA‐GFP was exported efficiently in wild type cells, but a twofold increase in periplasmic GFP was obtained when the TatABC components were co‐expressed. In both cases, periplasmic GFP peaked at about the 12 h point during fermentation but decreased thereafter, suggesting that proteolysis was occurring. Typical yields were 60 mg periplasmic GFP per liter culture. The cells over‐expressed the tat operon throughout the fermentation process and the Tat system was shown to be highly active over a 48 h induction period. Fed‐batch fermentation generated much greater yields: using glycerol feed rates of 0.4, 0.8, and 1.2 mL h−1, the cultures reached OD600 values of 180 and periplasmic GFP levels of 0.4, 0.85, and 1.1 g L−1 culture, respectively. Most or all of the periplasmic GFP was shown to be active. These export values are in line with those obtained in industrial production processes using Sec‐dependent export approaches. Biotechnol. Bioeng. 2012; 109: 2533–2542. © 2012 Wiley Periodicals, Inc.
Correlation of thrombosis growth rate to pathological wall shear rate during platelet accumulation
Authors: Bark David L. , Para Andrea N. , Ku David N.
Published: April 2012

Local hemodynamics may strongly influence atherothrombosis, which can lead to acute myocardial infarction and stroke. The relationship between hemodynamics and thrombosis during platelet accumulation was studied through an in vitro flow system consisting of a stenosis. Specifically, wall shear rates (WSR) ranging from 0 to 100,000 s−1 were ascertained through computations and compared with thrombus growth rates found by image analysis for over 5,000 individual observation points per experiment. A positive correlation (P < 0.0001) was found between thrombus accumulation rates and WSR up to 6,000 s−1, with a decrease in growth rates at WSR >6,000 s−1 (P < 0.0001). Furthermore, growth rates at pathological shear rates were found to be two to four times greater than for physiological arterial shear rates below 400 s−1. Platelets did not accumulate for the first minute of perfusion. The initial lag time, before discernible thrombus growth could be found, diminished with shear (P < 0.0001). These studies show the quantitative increase in thrombus growth rates with very high shear rates in stenoses onto a collagen substrate. Biotechnol. Bioeng. 2012; 109: 2642–2650. © 2012 Wiley Periodicals, Inc.
Using FlAsH To Probe Conformational Changes in a Large HEAT Repeat Protein
Authors: Tsytlonok Maksym , Itzhaki Laura S.
Published: April 2012

We have investigated the use of FlAsH, a small fluorogenic molecule that binds to tetracysteine motifs, to probe folding of the 15‐HEAT repeat protein PR65A. PR65A is one of a special class of modular non‐globular proteins known as tandem repeat proteins, which are composed of small structural motifs that stack to form elongated, one‐dimensional architectures. We were able to introduce linear and bipartite tetracysteine motifs at several sites along the α‐helical HEAT array of PR65A without disrupting the structure or stability. When the linear tetracysteine motif CCPGCC was used, FlAsH fluorescence reported globally on the folding of the protein. When the tetracysteine motif was displayed in bipartite mode through the engineering of pairs of cysteines on adjacent HEAT repeats, FlAsH fluorescence became a reporter of local conformation and of oligomerisation. Thus, by designing FlAsH‐binding sites at different locations along the repeat array one can interrogate specific properties of PR65A, paving the way for structure–function analysis of this protein both in vitro and in the cell.
Total Synthesis of Bistramide A and Its 36(Z) Isomers: Differential Effect on Cell Division, Differentiation, and Apoptosis
Authors: Tomas Loïc , Boije af Gennäs Gustav , Hiebel Marie Aude , Hampson Peter , Gueyrard David , Pelotier Béatrice , Yli‐Kauhaluoma Jari , Piva Olivier , Lord Janet M. , Goekjian Peter G.
Published: April 2012

The total synthesis of bistramide A and its 36(Z),39(S) and 36(Z),39(R) isomers shows that these compounds have different effects on cell division and apoptosis. The synthesis relies on a novel enol ether‐forming reaction for the spiroketal fragment, a kinetic oxa‐Michael cyclization reaction for the tetrahydropyran fragment, and an asymmetric crotonylation reaction for the amino acid fragment. Preliminary biological studies show a distinct pattern of influence of each of the three compounds on cell division, differentiation, and apoptosis in HL‐60 cells, thus suggesting that these effects are independent activities of the natural product.
One‐Step Synthesis of SnO2 and TiO2 Hollow Nanostructures with Various Shapes and Their Enhanced Lithium Storage Properties
Authors: Wang Zhiyu , Wang Zi Chen , Madhavi Srinivasan , Lou Xiong Wen (David)
Published: April 2012

A versatile one‐step method for the general synthesis of metal oxide hollow nanostructures is demonstrated. This method involves the controlled deposition of metal oxides on shaped α‐Fe2O3 crystals which are simultaneously dissolved. A variety of uniform SnO2 hollow nanostructures, such as nanococoons, nanoboxes, hollow nanorings, and nanospheres, can be readily generated. The method is also applicable to the synthesis of shaped TiO2 hollow nanostructures. As a demonstration of the potential applications of these hollow nanostructures, the lithium storage capability of SnO2 hollow structures is investigated. The results show that such derived SnO2 hollow structures exhibit stable capacity retention of 600–700 mAh g−1 for 50 cycles at a 0.2 C rate and good rate capability at 0.5–1 C, perhaps benefiting from the unique structural characteristics.
Enantioselective Intramolecular [2+2] Photocycloaddition Reactions of 4‐Substituted Coumarins Catalyzed by a Chiral Lewis Acid
Authors: Brimioulle Richard , Guo Hao , Bach Thorsten
Published: April 2012

Eight coumarins, which carry a terminal alkene tethered by a CH2XCH2 group to their 4‐position (X=CH2, CMe2, O, S, NBoc, NZ, NTs, NBn), were synthesized in overall yields of 51–80 %. Starting materials for the syntheses were either commercially available 4‐hydroxycoumarin or 4‐formylcoumarin. The intramolecular [2+2] photocycloaddition of these coumarins gave diastereoselectively products with a tetracyclic 3,3a,4,4a‐tetrahydro‐1H‐cyclopenta[2,3]cyclobuta[1,2‐c]chromen‐5(2H)‐one skeleton. Direct irradiation at λ=300 nm in dichloromethane (c=10 mM) led to product formation in good yields for most substrates, presumably via a singlet excited state intermediate. Due to the low coumarin absorption at λ >350 nm the photocycloaddition was slow upon irradiation at λ=366 nm. Addition of a chiral oxazaborolidine‐based Lewis acid (50 mol %) increased the reaction rate at λ=366 nm and induced a significant enantioselectivity in the [2+2] photocycloaddition. Six out of eight coumarin substrates (X=CH2, CMe2, O, NBoc, NZ, NTs) gave the respective products in yields of 72–96 % and with 74–90 % enantiomeric excess (ee) upon irradiation in dichloromethane (c=20 mM) at −75 °C. The Lewis acid presumably acts by coordination to the coumarin carbonyl oxygen atom, which leads to a bathochromic shift (redshift) of the UV absorption and which increases the singlet state lifetime. A second electrostatic interaction of the hydrogen atom at C3 with the oxygen atom of the oxazaborolidine is likely.
Solution‐Processed, Undoped, Deep‐Blue Organic Light‐Emitting Diodes Based on Starburst Oligofluorenes with a Planar Triphenylamine Core
Authors: Liu Cui , Li Yanhu , Zhang Yingyue , Yang Chuluo , Wu Hongbin , Qin Jingui , Cao Yong
Published: April 2012

A series of starburst oligomers (T1–T3) that contained a fully diarylmethene‐bridged triphenylamine core and oligofluorene arms were designed and synthesized through Suzuki cross‐coupling reactions. Their thermal, photophysical, and electrochemical properties were also investigated. These materials showed high glass transition, in the range of 123–129 °C, and good film‐forming abilities. They displayed deep‐blue emission both in solution and as thin films. Solution‐processed devices based on these oligomers exhibited highly efficient deep‐blue electroluminescence and the device performances were significantly enhanced with the extension of the oligofluorene arms. The double‐layered device that contained T3 as an emitter showed a maximum current efficiency of 3.83 cd A−1 and a maximum external quantum efficiency of 4.19 % with CIE coordinates of (0.16, 0.09), which are among the highest values for undoped deep‐blue OLEDs that are based on solution‐processable starburst oligomers.
How Charging Corannulene with One and Two Electrons Affects Its Geometry and Aggregation with Sodium and Potassium Cations
Authors: Zabula Alexander V. , Spisak Sarah N. , Filatov Alexander S. , Grigoryants Vladimir M. , Petrukhina Marina A.
Published: April 2012

Bowl‐shaped mono‐ and dianions are prepared by reduction of corannulene (C20H10, 1) with sodium and potassium metals in the presence of [18]crown‐6 ether. Single‐crystal X‐ray diffraction studies of two sodium salts, [Na(THF)2([18]crown‐6)]+[1−] (2 a) and [Na([18]crown‐6)]+[1−] (2 b), reveal the presence of naked corannulene monoanions 1− in both cases. In contrast, the potassium adduct, [K([18]crown‐6)]+[1−] (3), shows an η2‐binding of the K+ ion to the convex face of 1−. For the first time, corannulene dianions have been isolated as salts with sodium, [Na2([18]crown‐6)]2+[12−] (4 a) and [Na(THF)2([18]crown‐6)]+[Na([18]crown‐6)]+[12−] (4 b), and potassium counterions, [K([18]crown‐6)]2+[12−] (5). Their structural characterization reveals geometry perturbations upon addition of two electrons to a bowl‐shaped polyarene. It also demonstrates η5‐ or η6‐binding of metals to the curved carbon surface of 12−, depending on the crystallization conditions. Both mono‐ and doubly‐charged corannulene bowls show the preferential exo binding of Na+ and K+ ions in all investigated compounds. Various types of CH⋅⋅⋅π interactions are found in the crystals of 2–5. The UV/Vis, ESR, and 1H NMR spectroscopic studies of 2–5 indicate different coordination environment of corannulene anions in solution, depending on the metal ion.
ChemInform Abstract: Hexatellurium Rings in Coordination Polymers and Molecular Clusters: Synthesis and Crystal Structures of [M(Te6)]X3 (M: Rh, Ir; X: Cl, Br, I) and [Ru2(Te6)] (TeBr3)4(TeBr2)2.
Authors: Guenther Anja , Ruck Michael
Published: April 2012

Black crystals of [Rh(Te6)]Br3 (I), [Rh(Te6)]I3 (II), [Ir(Te6)]Cl3 (III), [Ir(Te6)]Br3 (IV), and [Ir(Te6)]I3 (V) are prepared from stoichiometric mixtures of Rh or Ir, Te, and TeX4 (X: Cl, Br, I; evacuated silica tube, 300—350 °C, 7 d).
ChemInform Abstract: All‐Boron Planar B6 Ring in the Solid‐State Phase Ti7Rh4Ir2B8.
Authors: Fokwa Boniface P. T. , Hermus Martin
Published: April 2012

Needle‐shaped silvery single crystals of the title compound are synthesized by arc‐melting of the elements under argon atmosphere.
ChemInform Abstract: Structural Studies on Ba2SrMg4F14 and Ba2MM′Mg4F14 (M: Ca, Sr, Ba).
Authors: Kubel Frank , Wandl Nicole , Pantazi Mariana
Published: April 2012

The new compound Ba2SrMg4F14 is synthesized by precipitation from an aqueous solution of Ba(OH)2, Sr(OH)2, and Mg(OAc)2 with NH4 followed by heating at 650 °C for 3 h in a Pt crucible.
ChemInform Abstract: Cation Ordering in the Double Tungstate LiFe(WO4)2.
Authors: Albino Marjorie , Pechev Stanislav , Veber Philippe , Velazquez Matias , Josse Michael
Published: April 2012

The structure of the title compound is reexamined by single crystal XRD (monoclinic, space group C2/c, Z = 4).
ChemInform Abstract: Curium(III) Borate Shows Coordination Environments of Both Plutonium(III) and Americium(III) Borates.
Authors: Polinski Matthew J. , Wang Shuao , Alekseev Evgeny V. , Depmeier Wulf , Liu Guokui , Haire Richard G. , Albrecht‐Schmitt Thomas E.
Published: April 2012

Crystals of Cm2 [B14O20(OH)7(H2O)2Cl] are prepared by reaction of CmCl3 with molten boric acid (autoclave, 240 °C, 7 d).
ChemInform Abstract: High‐Pressure Synthesis and Characterization of the Alkali Diazenide Li2N2.
Authors: Schneider Sebastian B. , Frankovsky Rainer , Schnick Wolfgang
Published: April 2012

Black powder of Li2N2 is prepared by decomposition of LiN3 in a Walker‐type multianvil assembly (9 GPa, 750 K, 50 min).
ChemInform Abstract: Solid‐State Structure of Bromine Azide.
Authors: Lyhs Benjamin , Blaeser Dieter , Woelper Christoph , Schulz Stephan , Jansen Georg
Published: April 2012

BrN3 is synthesized by reaction of NaN3 with Br2 at ‐196 °C, followed by slow warming to 25 °C.
ChemInform Abstract: Nanoscale Growth of Molecular Oxides: Assembly of a {V6} Double Cubane Between Two Lacunary {P2W15} Polyoxometalates.
Authors: Lydon Claire , Busche Christoph , Miras Haralampos N. , Delf Alexander , Long De‐Liang , Yellowlees Lesley , Cronin Leroy
Published: April 2012

The new Wells—Dawson sandwich compound (Bu4N)10 [P4V6W30O120]·4MeCN is synthesized by refluxing (Bu4)5 [H4P2W15V3O62] in MeCN for 5 d in the dark (95% yield).
ChemInform Abstract: New Solid Solution Fe1‐xCrxVSbO6 with Rutile‐Type Structure.
Authors: Filipek E. , Dabrowska G.
Published: April 2012

Title solid solutions with x = 0.05, 0.25, 0.50, 0.75, and 0.90 are synthesized by solid state reaction of V2O5, α‐Sb2O4, Cr2O3, and Fe2O3 as well as from mixtures of FeVSbO6 and CrVSbO6 (620, 650, 700, 750, and 800 °C for 24 h each).
ChemInform Abstract: A New Lindqvist Polyanion‐Based Three‐Dimensional Network with a NaCl Topology.
Authors: Li Shaobin , Pang Haijun , Ma Huiyuan , Wang Kun , Zhu Chuncheng
Published: April 2012

The new compound [Co(bipy)3][Mo6O19]·H2O is hydrothermally synthesized from a mixture of Na2MoO4, CoCl2, NH4VO3, bipy, and H2O (autoclave, 165 °C, 5 d, 62% yield).
ChemInform Abstract: Cs2NiO2 Revisited. Crystal Structure and Magnetic Properties.
Authors: Duris Katarina , Jansen Martin
Published: April 2012

Single crystals of Cs2NiO2 are prepared by the azide nitrate route from mixtures of NiO and an excess of CsNO3 and CsN3 (723 K, 100 h).
ChemInform Abstract: Synthesis and Structure Determination of Ag5HgSbO6, Comparison with AgHg3SbO6 and Ag5Pb2O6.
Authors: Klein Wilhelm , Jansen Martin
Published: April 2012

The new compound Ag5HgSbO6 is synthesized by solid state reaction of Ag2O, HgO, and Sb2O3 (100 MPa O2, 500 °C).
ChemInform Abstract: A Further Extension of Pnictide Oxide Chemistry — Synthesis and Structure of La2AuP2O.
Authors: Eul Matthias , Moeller Manfred H. , Hoffmann Rolf‐Dieter , Jeitschko Wolfgang , Poettgen Rainer
Published: April 2012

The title compound is synthesized from La filings, La2O3, Au, and red P in the ratio 1.33:0.33:1:2 (pressed pellets, evacuated silica tube, 1473 K, 48 h).
ChemInform Abstract: Development of an Intramolecular Gassman′s [2 + 2] Cycloaddition.
Authors: Feltenberger John B. , Ko Changhong , Deng Jun , Ghosh Sunil K. , Hsung Richard P.
Published: April 2012

The reaction of different oxygen‐, nitrogen‐, and carbon‐tethered acetals gives rise to fused cyclobutane derivatives.
ChemInform Abstract: Heterocyclization of 3‐(R‐Amino)‐3‐methylthio‐1‐phenylpropenones (I) and 5‐Benzoyl‐6‐methylthio‐1,2‐dihydropyridin‐2‐ones (X) with 1,2‐ and 1,3‐Dinucleophilic Reagents.
Authors: Britsun V. N. , Pikun N. V. , Ryabitskii A. B. , Lozinskii M. O.
Published: April 2012

Reactions of the title compounds (I) and (X) with N,N‐, N,C‐1,2‐ and 1,3‐dinucleophiles proceed regioselectively via [3 + 2]‐ or [3 + 3]cyclocondensation, in general.
ChemInform Abstract: Reactions of 3‐Aroylacrylates with α‐Aminoazoles.
Authors: Kolos N. N. , Kovalenko L. U. , Borovskoy V. A.
Published: April 2012

Cyclocondensation of 3‐aroylacrylates with α‐aminoazoles provides access to azolopyridine and ‐pyrimidine derivatives.
ChemInform Abstract: Unexpected Tandem Reaction of New Type Morita—Baylis—Hillman Adducts Promoted by [Hmim]HSO4/NaNO3 System.
Authors: Zhong Weihui , Wang Guan , Chen Kai
Published: April 2012

A tandem reaction of Baylis—Hillman adducts (I) proceeds in the ionic liquid [Hmim]HSO4 / NaNO3 system and the unexpected products (III) and (IV) are formed via rearrangement and substitution.
ChemInform Abstract: Sodium Borohydride—Nickel Chloride—Methanol Catalytic System for Regioselective Reduction of Electron‐Rich Conjugated Dienes and Reductive Cleavage of Allyl Esters Involving π‐Allylnickel Intermediates.
Authors: Yin Biao‐Lin , Cai Cong‐Bi , Lai Jin‐Qiang , Zhang Ze‐Ren , Huang Li , Xu Li‐Wen , Jiang Huan‐Feng
Published: April 2012

The chemoselective reduction of one double bond of various electron‐rich dienes, e.g. (I), (III), (V) and (XI) is smoothly achieved in the system NaBH4—NiCl2—MeOH.
ChemInform Abstract: A Simple and Efficient Bromoformyloxylation and Bromoacetoxylation Reaction Using TsNBr2.
Authors: Saikia Indranirekha , Rajbongshi Kamal Krishna , Phukan Prodeep
Published: April 2012

Reaction of a variety of olefins with DMF in the presence of TosNBr2 followed by hydrolysis offers a method for the regioselective synthesis of O‐formyl bromohydrins.
ChemInform Abstract: Nitrite Ionic Liquids (IL‐ONO and [bmim]NO2) as Effective Nitrosonium Sources for the Synthesis of α‐Oximinoketones under Mild Heterogeneous Conditions.
Authors: Valizadeh H. , Shomali A. , Gholipour H.
Published: April 2012

[bmim]NO2 is similarly efficient as nitrosonium source.
ChemInform Abstract: User‐Friendly [(Diglyme)NiBr2]‐Catalyzed Direct Alkylations of Heteroarenes with Unactivated Alkyl Halides Through C—H Bond Cleavages.
Authors: Ackermann Lutz , Punji Benudhar , Song Weifeng
Published: April 2012

Title reaction proceeds smoothly in the presence of a phosphor‐ and nitrogen‐free NiBr2—CuI—diglyme catalyst system to afford C‐2 alkylated benzoxazoles (III) and benzothiazoles (V) in moderate yields.
ChemInform Abstract: Triflic Acid Catalyzed Oxidative Lactonization and Diacetoxylation of Alkenes Using Peroxyacids as Oxidants.
Authors: Kang Yan‐Biao , Gade Lutz H.
Published: April 2012

A clean and efficient method to prepare 1,2‐diacetoxy alkanes from alkenes is reported.
ChemInform Abstract: Atmospheric Pressure Aminocarbonylation of Aryl Iodides Using Palladium Nanoparticles Supported on MOF‐5.
Authors: Dang Tuan T. , Zhu Yinghuai , Ghosh Subhash C. , Chen Anqi , Chai Christina L. L. , Seayad Abdul M.
Published: April 2012

An efficient synthesis of the amides (IV) and (VI) is presented by using a recyclable catalyst with a negligible palladium leaching.
ChemInform Abstract: Microwave‐Assisted Benzyl‐Transfer Reactions of Commercially Available 2‐Benzyloxy‐1‐methylpyridinium Triflate.
Authors: Wang Teng‐wei , Intaranukulkit Tanit , Rosana Michael R. , Slegeris Rimantas , Simon Janet , Dudley Gregory B.
Published: April 2012

The benzylation of various primary, secondary and tertiary aliphatic alcohols as well as phenols proceeds smoothly with title benzyloxypyridinium triflate (II) under microwave irradiation.
ChemInform Abstract: Diverse Trifluoromethyl Heterocycles from a Single Precursor.
Authors: Honey Mark A. , Pasceri Raffaele , Lewis William , Moody Christopher J.
Published: April 2012

The oxobutanoate (I) can smoothly be converted into trifluoromethylated oxazoles, thiazoles, imidazoles, triazines, and pyridines which are of biological interest.
ChemInform Abstract: Efficient Dimeric Esterification of Alcohols with NBS in Water Using L‐Proline as Catalyst.
Authors: Liu Xiuhong , Wu Jun , Shang Zhicai
Published: April 2012

A green and efficient method for the dimeric esterification of various aliphatic primary alcohols is developed (10 examples).
ChemInform Abstract: Intramolecular Pauson—Khand Reaction Catalyzed by Oxime‐Derived Palladacycles.
Authors: Wang Xue‐Rui , Lu Fu‐Hua , Song Yang , Lu Zhong‐Lin
Published: April 2012

Oxime‐derived palladacycles with a pyridine co‐ligand are tested and PACY is found to be optimal for the synthesis of bicyclic cyclopentenones.
ChemInform Abstract: Regio‐ and Stereoselective Synthesis of Cyclopentenones: Intermolecular Pseudo‐Pauson—Khand Cyclization.
Authors: Barluenga Jose , Alvarez‐Fernandez Ana , Suarez‐Sobrino Angel L. , Tomas Miguel
Published: April 2012

A one‐pot procedure is developed to synthesize polysubstituted cyclopentenones from bromoalkenes and carbene complexes.
ChemInform Abstract: Access to Dienophilic Ene‐Triketone Synthons by Oxidation of Diketones with an Oxoammonium Salt.
Authors: Eddy Nicholas A. , Kelly Christopher B. , Mercadante Michael A. , Leadbeater Nicholas E. , Fenteany Gabriel
Published: April 2012

Treatment of cyclohexadiones of type (I) with the oxoammonium salt shown in the scheme provides a new approach to ene‐triketones like (II).
ChemInform Abstract: Rhodium‐Catalyzed Asymmetric Arylation of N‐(tert‐Butanesulfinyl)imines with Sodium Tetraarylborates.
Authors: Reddy Leleti Rajender , Gupta Aditya P. , Villhauer Eric , Liu Yugang
Published: April 2012

The method allows a new, efficient, and highly stereoselective access to optically active α‐branched amines in a diastereomerically pure form.
ChemInform Abstract: Thermocontrolled Benzylimine—Benzaldimine Rearrangement over Nafion‐H Catalysts for Efficient Entry into α‐Trifluoromethylbenzylamines.
Authors: Prakash G. K. Surya , Glinton Kevin E. , Panja Chiradeep , Gurung Laxman , Battamack Patrice T. , Toeroek Bela , Mathew Thomas , Olah George A.
Published: April 2012

A convenient synthesis of benzaldimines from ketones and benzylamine is developed using Nafion or its silica‐supported analogue Nafion SAC‐13 as effective Broenstedt acid catalyst.
ChemInform Abstract: tert‐Butylnitrite as a Convenient and Easy‐Removable Oxidant for the Conversion of Benzylic Alcohols to Ketones and Aldehydes.
Authors: Hamasaki Akiyuki , Kuwada Hideyuki , Tokunaga Makoto
Published: April 2012

The method allows the oxidation to the corresponding carbonyl compounds without significant formation of the corresponding carboxylic acids.
ChemInform Abstract: β‐Alanine‐DBU: A Highly Efficient Catalytic System for Knoevenagel‐Doebner Reaction under Mild Conditions.
Authors: Zhu Lingjian , Lei Ning , Miao Zhenyuan , Sheng Chunquan , Zhuang Chunlin , Yao Jianzhong , Zhang Wannian
Published: April 2012

The presented reaction pathway proceeds smoothly at ambient temperature, tolerates a variety of functional groups and avoids side reactions.
ChemInform Abstract: Reactivity of Unsaturated 5(4H)‐Oxazolones with Hg(II) Acetate: Synthesis of Methyl N‐Benzoylamino‐3‐arylacrylates.
Authors: Roiban Gheorghe‐Doru , Soler Tatiana , Contel Maria , Grosu Ion , Cativiela Carlos , Urriolabeitia Esteban P.
Published: April 2012

The high‐yielding process affords the title compounds without changing the stereochemistry of the substrates.
ChemInform Abstract: A General Palladium‐Catalyzed Aminocarbonylation of Phenols to Primary Benzamides via in situ Generation of Aryl Nonaflates.
Authors: Wu Xiao‐Feng , Neumann Helfried , Beller Matthias
Published: April 2012

A mild, one‐pot procedure for the synthesis of benzamides from easily available phenols is reported.
ChemInform Abstract: Palladium‐Catalyzed Aminocarbonylation of Benzyl Chlorides Using Ammonia.
Authors: Wu Xiao‐Feng , Schranck Johannes , Neumann Helfried , Beller Matthias
Published: April 2012

An inexpensive palladium catalyst system and ammonia as the amine source are successfully applied for this atom‐efficient methodology.
ChemInform Abstract: Catalyst‐Free, Facile, and an Efficient Synthesis of α‐Aminonitriles Employing Zn(CN)2 as an Ecofriendly Cyanating Agent.
Authors: Shah Sakshi , Singh Baldev
Published: April 2012

The three‐component condensation process proceeds under very mild conditions in the absence of toxic, moisture‐sensitive catalysts or volatile solvents.
ChemInform Abstract: A One‐Pot Synthesis of Alkynyl Sulfides from Terminal Alkynes.
Authors: Zheng Weixin , Zheng Fenfen , Hong Ya , Hu Linfeng
Published: April 2012

Readily and commercially available substances are used in the convenient, safe, and atom‐economical synthesis of compounds (III) and (V).
ChemInform Abstract: Cross‐Coupling of Aryl Grignard Reagents with Aryl Iodides and Bromides Through SRN1 Pathway.
Authors: Shirakawa Eiji , Hayashi Yumi , Itoh Ken‐ichi , Watabe Ryo , Uchiyama Nanase , Konagaya Wataru , Masui Seiji , Hayashi Tamio
Published: April 2012

The reaction with aryl iodides or bromides proceeds without the need for a transition‐metal catalyst.
ChemInform Abstract: Ligand‐Free Hiyama Cross‐Coupling Reaction Catalyzed by Palladium on Carbon.
Authors: Yanase Takayoshi , Monguchi Yasunari , Sajiki Hironao
Published: April 2012

A wide range of aryl bromides and aryltrialkoxysilane derivatives (II) can be employed whereas, aryl chlorides give the desired products in only poor yields.
ChemInform Abstract: Silicotungstic Acid Catalyzed Claisen Schmidt Condensation Reaction: An Efficient Protocol for Synthesis of 1,3‐Diaryl‐2‐propenones.
Authors: Rajput Jaspreet , Kaur Gagandeep
Published: April 2012

The condensation of acetophenones with aldehydes proceeds highly chemoselective under neat conditions to yield the title compounds (III) as exclusive (E) isomers.
ChemInform Abstract: Stereoselective Synthesis of Melatonin Receptor Agonist Ramelteon via Asymmetric Michael Addition.
Authors: Zhang Xuan , Yuan Wei , Luo Yu , Huang Qing‐Qing , Lu Wei
Published: April 2012

A new approach to synthesize ramelteon (VII) and its analogue (IV) is presented via the highly effective and enantioselective title addition reaction as the key step.
ChemInform Abstract: Enantioselective [2 + 2 + 2] Cycloisomerization of Alkynes in the Synthesis of Helicenes: The Search for Effective Chiral Ligands.
Authors: Stara Irena G. , Andronova Angelina , Kollarovic Adrian , Vyskocil Stepan , Juge Sylvain , Lloyd‐Jones Guy C. , Guiry Patrick J. , Stary Ivo
Published: April 2012

In order to construct helicene backbones in nonracemic form under Ni(0) catalysis, a large collection of phosphorus ligands is tested to achieve an enantioselective cycloisomerization of aromatic triynes.
ChemInform Abstract: Effect of Substituents in the Propynyl Fragment and at the Nitrogen Atom on the Intramolecular Cyclization of (3‐Aryl‐2‐propynyl)‐(4‐hydroxy‐2‐butynyl)ammonium Chlorides and also on the Recyclization of the Products Formed.
Authors: Khachatryan A. A.
Published: April 2012

The influence of the reaction conditions on the intramolecular cyclization/recyclization cascade is discussed taking also substituent effects into consideration.
ChemInform Abstract: Palladium‐Catalyzed Direct Arylation of Polysubstituted Benzofurans.
Authors: Carrer Amandine , Brinet Dimitri , Florent Jean‐Claude , Rousselle Patricia , Bertounesque Emmanuel
Published: April 2012

A straightforward and widely applicable method is reported.
ChemInform Abstract: Direct Arylation of Arene and N‐Heteroarenes with Diaryliodonium Salts Without the Use of Transition Metal Catalyst.
Authors: Wen Jun , Zhang Ruo‐Yi , Chen Shan‐Yong , Zhang Ji , Yu Xiao‐Qi
Published: April 2012

It allows a new and simple access to various biaryl structures.
ChemInform Abstract: Palladium‐Catalyzed Direct Arylations of NH‐Free Pyrrole and N‐Tosylpyrrole with Aryl Bromides.
Authors: Bheeter Charles Beromeo , Bera Jitendra K. , Doucet Henri
Published: April 2012

The arylations are highly regioselective in favor of the C‐2 position.
ChemInform Abstract: 1,3‐Dipolar Cycloaddition Reaction in Porphyrin Systems with Functionalized Alkyl Nitrile Oxides — Synthesis of Isoxazoline‐Fused Chlorins.
Authors: Wyrebek Przemyslaw , Mikus Agnieszka , Ostrowski Stanislaw
Published: April 2012

An approach to fused isoxazoline‐type chlorins (III) by dipolar [3 + 2]cycloaddition of in situ generated alkyl nitrile oxides to meso‐tetraphenylporphyrin is presented.
ChemInform Abstract: Rhodium(I)‐Catalyzed [3 + 2] Intramolecular Cycloaddition of Alkylidenecyclopropane‐Propargylic Esters.
Authors: Zhang Di‐Han , Shi Min
Published: April 2012

The title reaction under conditions A) affords highly unsaturated isoindoline structures.
ChemInform Abstract: Rhodium‐Catalyzed Addition of Boronic Acids to Vinylogous Imines Generated in situ from Sulfonylindoles.
Authors: Cao Liang‐Liang , Ye Zhi‐Shi , Jiang Guo‐Fang , Zhou Yong‐Gui
Published: April 2012

A variety of aryl‐ and alkyl‐substituted sulfonylindoles smoothly undergoes Rh‐catalyzed arylation reaction to give indole derivatives (III), (V), (VII) in moderate to excellent yields.
ChemInform Abstract: First Example of the Reaction of Unsymmetrical Dienones with a 1,3‐Dipole. Synthesis of Spiropyrrolidines.
Authors: Klochkova I. N. , Aniskov A. A. , Schekina M. P.
Published: April 2012

The three‐component reaction between isatin, unsymmetrical dienones (II), and sarcosine (III) yields a mixture of novel regioisomeric spiropyrrolidines (IV) and (V).
ChemInform Abstract: Ni(ClO4)2‐Catalyzed Regio‐ and Diastereoselective [3 + 2] Cycloaddition of Indoles and Aryl Oxiranyl‐dicarboxylates/Diketones: A Facile Access to Furo[3,4‐b]indoles.
Authors: Zhang Jieming , Chen Zuliang , Wu Hai‐Hong , Zhang Junliang
Published: April 2012

In most cases, the endo‐isomer is also formed as minor product.
ChemInform Abstract: Ionic Diamine Rhodium Complex Catalyzed Reductive N‐Heterocyclization of N‐(2‐Nitroarylidene)amines.
Authors: Okuro Kazumi , Gurnham Joanna , Alper Howard
Published: April 2012

A simple protocol allows the transformation of substrates (I) in the presence of carbon monoxide to yield the corresponding 2H‐indazoles.
ChemInform Abstract: Diphenylparabanic Acid as a Synthon for the Synthesis of α‐Diketones and α‐Ketocarboxylic Acids.
Authors: Watanabe Nobuko , Hamano Mitsutaka , Todaka Shota , Asaeda Takahiro , Ijuin Hisako K. , Matsumoto Masakatsu
Published: April 2012

A number of symmetrical and unsymmetrical α‐diketones and α‐ketocarboxylic acids can be prepared.
ChemInform Abstract: Powerful Approach to Heterocyclic Skeletal Diversity by Sequential Three‐Component Reaction of Amines, Isothiocyanates, and 1,2‐Diaza‐1,3‐dienes.
Authors: Attanasi Orazio A. , Bartoccini Silvia , Favi Gianfranco , Giorgi Gianluca , Perrulli Francesca Romana , Santeusanio Stefania
Published: April 2012

The method is highly efficient for the preparation of 2‐thiohydantoins and 2‐iminothiazolidinones.
ChemInform Abstract: Intramolecular Carbonyl Nitroso Ene Reaction Catalyzed by Iron(III) Chloride/Hydrogen Peroxide as an Efficient Tool for Direct Allylic Amination.
Authors: Atkinson Duncan , Kabeshov Mikhail A. , Edgar Mark , Malkov Andrei V.
Published: April 2012

Title reaction is successfully applied to the oxidative ring closure of hydroxamic acids towards oxazolidinones, e.g. (II), (IV), (VI) and (X).
ChemInform Abstract: Enantioselective Cyclization Reactions of (Z)‐N‐Benzoyl‐α‐dehydro(1‐naphthyl)alanine N′‐Arylamides Initiated by Photoinduced Electron Transfer from Chiral Prolinol.
Authors: Yadai Hiroyuki , Sato Yuhki , Igarashi Tetsutaro , Sakurai Tadamitsu
Published: April 2012

The irradiation of amide (I) in the presence of a prolinol catalyst leads to a diastereomeric mixture of dihydrooxazoles (II) and (III) in low to moderate enantioselectivities, whilst the analogous reaction of compound (IV) provides racemic diastereomers (V) and (VI).
ChemInform Abstract: Synthesis of 6‐Substituted 2‐Pyrrolyl and Indolyl Benzoxazoles by Intramolecular O‐Arylation in Photostimulated Reactions.
Authors: Vaillard Victoria A. , Guastavino Javier F. , Buden Maria E. , Bardagi Javier I. , Barolo Silvia M. , Rossi Roberto A.
Published: April 2012

Irradiation of amides of type (I), (IIII), and (V) allows a simple and efficient access to pyrrolyl and indolyl benzoxazoles.
ChemInform Abstract: C‐[o‐(p‐Tolyl)sulfinyl]phenylnitrones. Synthesis and Reactivity in [3 + 2] Dipolar Cycloadditions.
Authors: Garcia Ruano Jose Luis , Fraile Alberto , Nunez Alberto , Martin M. Rosario , Alonso Ines
Published: April 2012

Title nitrones (III) react with different dipolarophiles to afford corresponding isoxazolidines.
ChemInform Abstract: Reactions of 2‐Diazo‐1,3‐dicarbonyl Compounds with Aromatic Thioketones (Superdipolarophiles).
Authors: Nikolaev V. A. , Ivanov A. V. , Shakhmin A. A. , Schulze B. , Rodina L. L.
Published: April 2012

Diazocarbonyl compounds (I) and (IV) react with thioketone (II) to give tetrasubstituted 1,3‐oxathioles (III) or (V), respectively.
ChemInform Abstract: Novel Thiazolone Derivatives of N‐Aryl‐β‐alanines.
Authors: Stasevych M. , Lubenets V. , Musyanovych R. , Novikov V. , Mickevicius V. , Beresnevicius Z. I. , Rutkauskas K.
Published: April 2012

Novel 4‐thiazolone derivatives of N‐aryl‐β‐alanines are synthesized by reaction of (I) with monochloroacetic acid or maleic anhydride.
ChemInform Abstract: La(OTf)3‐Catalyzed One‐Pot Synthesis of meso‐Substituted Porphyrinic Thiazolidinones.
Authors: Bhatt Ranjan K. , Sharma Satyasheel , Nath Mahendra
Published: April 2012

An improved procedure is used for the selective nitration of a phenyl group of meso‐tetraphenylperphyrin (I).
ChemInform Abstract: Unexpected Synthesis of 3‐(2‐Aminothiazol‐5‐yl)‐3‐arylpropanoates Through a One‐Pot Four‐Component Procedure.
Authors: Li Zheng , Li Yanbo
Published: April 2012

The title compounds (V) (9 examples) are efficiently obtained by a catalyst‐free, one‐pot four‐component reaction of 2‐aminothiazole, various aromatic aldehydes, Meldrum′s acid, and aliphatic alcohols.
ChemInform Abstract: 1,3‐Dibromo‐5,5‐dimethylhydantoin Catalyzed One‐Pot Synthesis of 2‐Arylbenzothiazoles.
Authors: Yang Xiaojuan , Liang Jinying
Published: April 2012

A simple, convenient and efficient method for the synthesis of 2‐arylbenzothiazoles using 1,3‐dibromo‐5,5‐dimethylhydantoin as catalyst is reported and a possible mechanism is proposed.
ChemInform Abstract: Electrophilic Heterocyclization of 4,5‐Disubstituted 3‐Allylthio‐4H‐1,2,4‐triazoles by the Action of Halogens.
Authors: Usenko R. M. , Slivka M. V. , Lendel V. G.
Published: April 2012

Electrophilic heterocyclization of 3‐allylthiotriazoles (I) by action of bromine or iodine results in the regioselective formation of thiazolotriazolium salts [cf.