bluuebunny/crossref_metadata_2025 huggingface dataset:
A digital taxation model for Nigeria: standardizing collection through technology integration
Authors: Ifeanyi Chukwunonso Okeke  , Edith Ebele Agu  , Onyinye Gift Ejike  , Chikezie Paul-Mikki Ewim  , Mobolaji Olalekan Komolafe
Published: September 2024

This paper introduces a digital taxation model for Nigeria, aimed at standardizing tax collection through advanced technology integration. The model addresses the critical need for modernizing Nigeria’s tax administration to enhance efficiency, accuracy, and compliance in tax collection processes. By leveraging digital technologies, the proposed model seeks to streamline tax administration, reduce manual errors, and improve overall tax revenue management. The model advocates for the implementation of a comprehensive digital tax infrastructure, including the development of an integrated tax management system, digital payment platforms, and real-time data analytics tools. This approach emphasizes the use of application programming interfaces (APIs) for seamless interaction between tax authorities, financial institutions, and taxpayers, ensuring a unified and efficient tax collection system. Blockchain technology is proposed to enhance transparency and traceability, providing an immutable ledger for all transactions, which helps in mitigating fraud and increasing taxpayer confidence. The digital taxation model also includes automated compliance monitoring and reporting systems that utilize artificial intelligence (AI) for predictive analytics and risk assessment. These systems are designed to identify discrepancies, flag potential non-compliance issues, and provide actionable insights to both tax authorities and businesses. Additionally, the model emphasizes the importance of taxpayer education and support, advocating for user-friendly digital platforms and resources to facilitate smooth adoption and compliance. Expected outcomes of the model include increased tax revenue through improved compliance and reduced tax evasion, enhanced operational efficiency for tax authorities, and a more transparent and equitable taxation process. By aligning with global best practices and integrating cutting-edge technologies, the digital taxation model aims to transform Nigeria’s tax administration landscape, fostering a more robust and reliable financial system.
A theoretical model for harmonizing local and international product standards for Nigerian exports
Authors: Ifeanyi Chukwunonso Okeke  , Edith Ebele Agu  , Onyinye Gift Ejike  , Chikezie Paul-Mikki Ewim  , Mobolaji Olalekan Komolafe
Published: September 2024

The development of a theoretical model for harmonizing local and international product standards for Nigerian exports is essential for enhancing the global competitiveness of the country's products. This model addresses the existing challenges that Nigerian exporters face, such as inconsistencies between domestic regulations and international standards, which hinder market access and reduce export potential. By aligning local standards with globally recognized frameworks, this model seeks to bridge regulatory gaps, improve product quality, and increase market acceptance. The model emphasizes a phased approach, beginning with the identification of priority sectors and key export products, followed by the establishment of standardized guidelines that comply with both local and international requirements. It incorporates stakeholder engagement, including collaboration with regulatory bodies, industry players, and international trade organizations, to ensure comprehensive input and compliance. Additionally, the model introduces capacity-building initiatives aimed at equipping Nigerian manufacturers and exporters with the necessary skills and knowledge to meet these standards. It also outlines mechanisms for continuous monitoring, evaluation, and updates to ensure alignment with evolving international trade regulations and market demands. The expected outcomes include improved product quality, enhanced consumer confidence in Nigerian exports, and expanded market share in global markets. This harmonization process will not only benefit Nigerian exporters but also contribute to national economic growth by promoting a more sustainable export sector and reducing non-tariff barriers.This theoretical framework provides a roadmap for policymakers, regulatory agencies, and industry stakeholders to work collaboratively toward creating an export ecosystem that thrives on compliance, quality, and competitiveness. Future research should explore the practical application of this model and assess its impact on the performance of key Nigerian export industries.
A Study on the Availability of Finfish and Shellfish of Junput Mangrove, East Midnapore, West Bengal, India
Authors: Bhunia Tapas , Saxena Shriparna , Payra Pijush
Published: September 2024

The fish species diversity is the most important indicator of health of aquatic environment. A good piscina ecosystem diversity illustrates the equable environment. The present study deals with the variety of fishes in the Junput mangrove area (Biramput to Haripur), East Midnapore district. The Junput mangrove area is located at the northern end of the Bay of Bengal (Latitude- 21°94'04.5"N Longitude- 87°26'59.5"E), West Bengal. The field study was taken for a season of two years and data are collected monthly basis were made from May 2022 to April 2024. The study results of the actual inquiry express the occurrence of 93 species (51 finfishes and 42 shellfishes). 51 finfishes belonging to 44 genera, 34 different family and 18 orders and 42 shellfishes belonging to 26 different genera, 15 different family and 03 orders. Among the rerecorded finfish species, 2 species were Vulnerable (VU), 01 species were Near Threatened (NT), 35 species were Least Concern (LC) while 06 species were Not Evaluated (NE), 07 species were Data Deficient (DD) with 44 genus, 18 orders and 34 families. In the case of recorded shellfish species, 33 species were Not Evaluated (NE), 06 species were Least Concern (LC) and 03 species were Data Deficient (DD) with 26 genus, 03 orders and 15 families. The number  of species richness in the order Decapoda were dominated by 39 species followed by Perciformes with 08 species; Clupeiformes with 07 species; Tetradontiformes with 05 species; both Gobiformes and Anguilliformes with 04 species; both Acanthuriformes and Carangiformes with 03 species; Siluriformes, Spariformes, Pleuronectiformes, Mugilliformes, Scombriformes, Aulopiformes and Xiphosurida with 02 species; Myliobactiformes, Cypriniformes, Carcharniformes, Elopiformes, Beloniformes and Stomatopoda with 01 species. Out of 93 finfish and shellfish, 50 were carnivores, 39 were omnivores, and 02 were each herbivores and detritivores.
ANAOKULLARINDA KULLANILAN RENKLERİN YEMEK ALANLARI ÖZELİNDE İNCELENMESİ
Authors: Topgül Çağla , Elibol Gülçin Cankız
Published: September 2024

İnsan yaşamının temelini oluşturan okul öncesi dönem, bir çocuğun yetişkin bir birey olma sürecinde önemli bir yere sahiptir. Bu dönemde çocuğun sağlıklı bir aile ortamında büyümesinin öneminin yanında sosyal ve fiziksel gelişim sürecini destekleyecek niteliğe sahip ortamlarda bulunması da sağlıklı bir birey olarak yetişmesi açısından son derece önemlidir. Bu anlamda ele alındığında, okul öncesi eğitim kurumları; çocuğun ihtiyaçlarına uygun ortamlar sunan, yaş grubunun özellikleri ve bireysel gelişim özellikleri doğrultusunda eğitim ve öğretim sağlayan mekanlar olarak çocuğun yetişmesi sürecinde önemli bir rol oynamaktadır.
Bu çalışma, çocuğun fiziksel ve sosyal gelişiminde aileden sonra en etkili ortam olan okul öncesi eğitim kurumlarından anaokullarının yemek alanlarında tercih edilen renkleri genel bir perspektifte ele almayı ve okul öncesi eğitim kurumlarının iç mekan tasarımlarının gelişimine bu yolla dolaylı katkı sağlamayı amaçlamaktadır. Çalışma kapsamında, renk kavramı ve renklerin mekan algısına etkisi üzerine geniş bir literatür taraması gerçekleştirilmiştir. Nitel araştırma yöntemi uygulanan bu çalışmada, literatür bilgileri doğrultusunda anaokullarının yemek mekanlarında kullanılan renklere dair değerlendirme yapabilmek amacıyla ihtiyaç duyulan veriler doküman taraması yöntemiyle elde edilmiş ve doküman analizi yöntemi ile incelenmiştir. Bu doğrultuda, İstanbul ilinde bulunan, Milli Eğitim Bakanlığı’na bağlı anaokullarının resmi internet sayfalarında yer alan yemek alanlarına ait görsellerden yararlanılarak doküman analizi gerçekleştirilmiş olup, yemek alanlarında bulunan masa, oturma elemanları, duvar ve zemin döşemelerindeki renk tercihleri karşılaştırmalı olarak incelenmiştir. Elde edilen verilere göre; anaokullarında en çok beyaz rengin tercih edildiği, bunu sırasıyla turuncu, ahşap tonları, kırmızı, yeşil, sarı, mavi ve krem renklerinin takip ettiği; en az kullanılan renklerin ise pembe, mor ve gri olduğu tespit edilmiştir.
STRATEGI MENINGKATKAN HASIL BELAJAR GEOGRAFI MELALUI PENERAPAN MODEL PEMBELAJARAN DISCOVERY LEARNING PADA SISWA KELAS XII IPS-3 SMAN 2 MAJENE SULAWESI BARAT)
Authors: Zhiddiq Sulaiman , Syamsul Putri A , Syarif Erman , Yusuf Muhammad , Mannan Abdul
Published: September 2024

This Classroom Action Research aims to determine whether the application of the discovery learning model can improve the geography learning outcomes of students of class XII-IPS3 SMAN 2 Majene. Initial observations showed that the learning process was less dynamic, the students' learning outcomes had not met the KKM, besides that because they had not or did not use a learning model. Therefore, this research took the topic of applying the discovery learning model in the hope of improving learning outcomes. The results of this study showed an increase in learning outcomes by using the discovery learning model seen from the average value of learning outcomes in cycle I which was 75.86 with a percentage of classical learning completeness of 31.03% then increased in cycle II with an average value of 88.62 with a percentage of classical learning completeness of 86.20%.
ANALISIS PERUBAHAN GARIS PANTAI DI KABUPATEN TAKALAR MENGGUNAKAN SISTEM INFORMASI GEOGRAFI TAHUN 2014-2024
Authors: Dermawan Dermawan , Malik Abdul , Mannan Abdul
Published: September 2024

Penelitian ini bertujuan untuk mengetahui perubahan garis Pantai di Kabupaten Takalar dengan menggunakan Sistem Informasi Geografi pada tahun 2014-2024. Jenis Penelitian yang digunakan yakni penelitian Deskriptif dengan pendekatan kuantitatif berupa angka-angka perubahan luas garis Pantai yang disebabkan karena terjadinya abrasi atau akresi. Penelitian ini berlokasi di kabupaten Takalar yang yang berlangsung selama 2 bulan. Adapun Hasil dalam penelitian ini yakni terjadi perubahan garis Pantai yang terjadi di kabupaten Takalar yang disebabkan karena terjadi abrasi dan akresi. Diketahui perubahan garis pantai yang disebabkan terjadinya abrasi di kabupaten takalar seluas 416,75 ha. Dimana kecamatan Mangarabombang dengan luasan abrasi terparah sebanyak 319, 85 ha, kecamatan Galesong Selatan 51, 16 ha, kecamatan galesong 16, 33 ha, kecamatan Sanrobone 13, 12 ha, kecamatan Mappaksunggu 12, 83 ha, dan kecamatan yang memiliki tingkat abrasi terendah dengan luasan abrasi sebesar 3, 46 ha. Sedangkan perubahan seluruh garis Pantai di kabupaten Takalar yang disebabkan karena terjadinya akresi sebesar 46,33 ha pada tahun 2014-2024. Tingkat akresi  tertinggi berada di kecamatan  Galesong Utara sebesar 19,31 ha, kecamatan mangarabombang memiliki tingkat akresi dengan luasan 12,69 ha, sedangkan daerah lain memiliki tingkat akresi dibawah 10 ha, dan daerah kecamatan galesong sama sekali tidak terjadi akresi pada daerah tersebut..
The IAEA Ocean Acidification International Coordination Centre Capacity Building Program: Empowering Member States to Address and Minimize the Impacts of Ocean Acidification
Authors:   International Atomic Energy Agency, Dupont Sam , Edworthy Carla , Sanchez-Noguera Celeste , Metian Marc , Fredrich Jana , Flickinger Sarah , Bantelman Ashley , Galdino Carolina , Graba Frank , Anghelici Olga , Hansson Lina
Published: September 2024

Ocean acidification (OA) is broadly recognized as a major problem for marine ecosystems worldwide, with follow-on effects to the economies of ocean-dependent communities. The urgent need to mitigate and minimize the impacts of OA is a scientific and political priority, as highlighted by the latest Intergovernmental Panel on Climate Change report (IPCC, 2022) and by the inclusion of OA as a target in the United Nations Sustainable Development Goals (SDG). In addition, over 20 years of strong scientific evidence on the impacts of OA provides compelling arguments for urgent CO2 mitigation. Reducing CO2 emissions will require ambitious regulatory and economic instruments, as well as effective systemic changes across governments and societies. It is critical to implement adaptation measures to minimize the impact of OA, among other key environmental stressors, as the mitigation process takes time, and the impacts of OA are already felt globally. Assessing the impacts of solutions and their potential implementations requires information at local scales, considering the variabilities in marine ecosystem responses to OA (e.g., local adaptation, species redundancies).
Numerical analysis of extended end-plate connections under dynamic loading
Authors: Aouiche Djamel , Lahbari Noureddine , Belhadj Mourad
Published: September 2024

An experimental investigation was conducted at Delft University of Technology to examine the behavior of eight statically loaded extended end plate moment connections up to collapse. The parameters investigated were the end plate thickness (10 mm, 15 mm, and 20 mm) and steel grade of the end plate (S355, S690). While the study was limited to a static test, this investigation intends to analyze the dynamic behavior of the research specimens (FS1 to FS4) using finite element methods. The multi-purpose software Abaqus was used to develop the 3D model. The mechanical properties of these connections, including strength, ductility, and energy dissipation capacity, are examined. The cyclic loading is applied according to the JGJ 101-96 standard specification. The finite element model was validated against experimental tests for both static and dynamic conditions, successfully reproducing moment-rotation curves and simulating ductile damage as well. The results indicate that increased plate thickness corresponds to improved stiffness and strength, while the use of higher steel grades introduces a delayed yield point and may reduce ductility, which must be balanced to optimize performance considering specific design requirements and loading conditions. Our findings align with previous findings and underscore the need for a better understanding of joint behavior under dynamic loading for seismic design since the strain rate at which load is applied significantly affects the material properties, which can significantly affect the performance of blast-resistant structures.
Evaluation of Machine Learning Algorithms and Methods for Improved Predictions in Cryptocurrency in Short-Time Horizons
Authors: Henesey Lawrence , Tkach Volodymyr , Parkhomenko Pavlo , Pingali Kiran
Published: September 2024

Cryptocurrency has the potential to reshape financial systems and introduce financial investments that are inclusive in nature, which has led to significant research in the prediction of cryptocurrency prices by employing artificial neural networks and machine learning models. Accurate short-term predictions are essential for optimizing investment strategies, minimizing risks, and ensuring market stability. Prior studies in time-series forecasting have successfully employed statistical methods like Auto-Regressive Integrated Moving Average (ARIMA) and machine learning algorithms such as Long Short-Term Memory (LSTM). The research results presented in this paper evaluate various statistical and machine learning algorithms, assessing their accuracy and effectiveness in modeling volatile cryptocurrency data for short-term forecasting. Additionally, the study explores diverse hyperparameter settings to enhance the performance of machine learning models. The highest performance is achieved by a hybrid model combining LSTM and Deep Neural Network (DNN), showcasing its effectiveness in forecasting cryptocurrency prices with improved accuracy and capability.
Understanding the Neurovascular Bundle in Ventral Hernia Repair
Authors: Shrivastava Rajesh , Shaikh Nazrah
Published: September 2024

A ventral hernia is an abnormal protrusion of an organ or tissue through a defect in the anterior abdominal wall. Such defects may occur spontaneously or arise due to a weakened abdominal wall musculature or due to previous surgical incisions. Despite being a common surgical condition, ventral hernias can prove to be a complex clinical entity, especially due to the myriad of techniques available for their repair. A common crucial denominator in all these procedures is the meticulous identification, handling and preservation of the neurovascular bundle. It is imperative to have a thorough understanding of the anatomy of the abdominal wall including it’s fascia, musculature and neurovascular structures, in order to ensure good clinical outcomes and prevent further complications. This chapter shall explore the detailed anatomy of the neurovascular bundle, it’s clinical significance and role in ventral hernia repairs and strategies to avoid damage to the neurovascular bundle and further complications.
Comparative Effectiveness of Teledermatology Versus In-person Consultations: A Systematic Review of Diagnostic Information Elements
Authors: Parandeh Ronak , Shajirat Zeinab , Pazyar Nader , Azizi Amirabbas
Published: September 2024

Context: Teledermatology is delivered through two primary methods: Live video conferencing, which enables real-time interaction between patients and doctors, and the store-and-forward technique, where images of skin lesions are sent over the internet for later examination. Objectives: This systematic review evaluates the concordance between in-person and telemedicine follow-up methods in dermatology. Methods: In February 2024, a comprehensive literature search was conducted across PubMed, Medline, ISI Web of Science, and the ACM Digital Library. Keywords such as "teledermatology," "telemedicine," and "mobile health" were used, following the PICOS criteria. Results: Initially, 716 articles were identified from the databases, along with four studies from the gray literature search. After removing duplicates, screening studies, and applying the inclusion and exclusion criteria, 21 studies were selected for the final review. These studies detailed follow-up procedures and assessed both direct and indirect costs and effectiveness. The consensus indicates that teledermatology reduces costs and satisfies both patients and healthcare professionals. Conclusions: Teledermatology has been shown to potentially increase the efficiency of follow-up care compared to traditional methods. However, further research is needed to develop standardized evaluation protocols and to more accurately measure and validate key variables. Publications suggest that teledermatology is cost-effective, reduces patient wait times, extends access to dermatological care in remote areas, and enhances satisfaction among patients, doctors, and nurses.
Anak yang Berhadapan dengan Hukum ditinjau dalam Pertanggungjawaban Hukum Sesuai dengan Sistem Peradilan Anak
Authors: Wartawan Wawan
Published: September 2024

Penelitian ini membahas tentang anak yang berhadapan dengan hukum ditinjau dalam pertanggungjawaban hukum sesuai dengan sistem peradilan anak. Pertanyaan mengenai sejauh mana anak dapat dimintai pertanggungjawaban atas tindakan kriminal yang anak lakukan telah kontroversial dalam sistem peradilan anak. Beberapa negara menerapkan sistem hukum yang ketat, dimana anak dapat dikenai sanksi yang sama dengan orang dewasa, sedangkan negara lain mengadopsi pendekatan rehabilitasi dan reintegrasi. Dampak dari pendekatan yang diterapkan terhadap pertanggungjawaban hukum anak sebagai pelaku tindak pidana berat dapat mempengaruhi masa depan anak tersebut. Pendekatan yang berfokus pada rehabilitasi dan reintegrasi memberikan kesempatan bagi anak untuk mendapatkan pemulihan dan kesempatan kedua dalam masyarakat. Namun, pendekatan yang mengedepankan hukuman dapat berpotensi merugikan anak dan menghambat proses rehabilitasi anak. Dalam konteks ini perlu adanya pendekatan yang berimbang dan komprehensif dalam memperlakukan anak sebagai pelaku tindak pidana berat menjadi penting. Perlindungan hak-hak anak, pembinaan moral dan pendekatan yang berlandaskan pada kepentingan terbaik anak harus menjadi landasan dalam sistem peradilan anak.
Pengembangan Media Chemuno Card Games (Ccg) Berbasis Model Scientific Critical Thinking (Sct) untuk Meningkatkan Keterampilan Berpikir Kritis Peserta Didik pada Materi Sistem Periodik Unsur
Authors: Khalidah Khalidah , Rusmansyah Rusmansyah , Almubarak Almubarak
Published: September 2024

Keterampilan berpikir kritis merupakan kemampuan dalam menganalisis suatu situasi berdasarkan fakta, bukti hingga diperolehnya suatu kesimpulan. Penelitian pengembangan media Chemuno Card Games (CCG) berbasis model Scientific Critical Thinking (SCT) pada materi sistem periodik unsur bertujuan untuk mengetahui kevalidan, kepraktisan, dan kefektifan media CCG berbasis model SCT untuk meningkatkan keterampilan berpikir kritis peserta didik. Penelitian ini menggunakan pengembangan model evaluatif Tessmer yaitu: self evaluation, expert review, one-to-one evaluation, small group evaluation, field test evaluation. Subjek penelitian ini yaitu 5 orang validator dan 31 peserta didik kelas X.G SMA Negeri 1 Kandangan. Teknik pengumpulan data menggunakan instrumen tes dan non tes (angket respon dan lembar observasi). Berdasarkan hasil uji coba menunjukkan media yang dikembangkan sangat valid dengan skor validitas 93, 11%, sangat praktis dengan skor kepraktisan 88,68% dan efektif dengan skor efektivitas 83,15%. Pembelajaran menggunakan media chemuno card yang dikembangkan meningkatkan keterampilan berpikir kritis peserta didiik yang ditunjukkan dengan nilai N-Gain pada kategori tinggi yaitu 0,83. Hasil analisis menunjuukan media chemuno card yang dikembangkan valid, praktis dan efektif untuk digunakan sebagai bahan ajar dalam pembelajaran kimia materi sistem periodik unsur untuk meningkatkan keterampilan berpikir kritis peserta didik.
Source, Name of Marker Compounds and Their Chemical Nature, Medicinal Uses and Health Benefits of Following Used as Nutraceuticals/Functional Foods-II
Authors: Goel Ms. Neha
Published: September 2024

This section of Nutraceuticals-II explores the nutraceutical and functional food applications of Garlic, Broccoli, Ginkgo, and Flaxseeds, focusing on their source, marker compounds, chemical nature, medicinal uses, and health benefits. Garlic, derived from *Allium sativum*, is rich in allicin, a sulfur-containing compound with potent antioxidant and antimicrobial properties, known for its cardiovascular benefits, including lowering blood pressure and cholesterol levels. Broccoli, a cruciferous vegetable, contains sulforaphane, a sulfur-rich compound that supports detoxification processes and offers protective effects against cancer. Ginkgo, sourced from *Ginkgo biloba* leaves, is known for its flavonoid glycosides and terpenoids, which enhance cognitive function and improve blood circulation. Flaxseeds are high in alpha-linolenic acid (ALA), an omega-3 fatty acid, and lignans, both of which contribute to heart health, anti-inflammatory effects, and hormonal balance. This study provides a comprehensive understanding of how these natural substances contribute to overall health, emphasizing their importance in disease prevention and health promotion.
Ethical and Regulatory Perspectives on Generative Artificial Intelligence in Pathology
Authors: Jackson Brian R. , Rashidi Hooman H. , Lennerz Jochen K. , de Baca M. E.
Published: September 2024

Context.—

Technology companies and research groups are increasingly exploring applications of generative artificial intelligence (GenAI) in pathology and laboratory medicine. Although GenAI holds considerable promise, it also introduces novel risks for patients, communities, professionals, and the scientific process.

Objective.—

To summarize the current frameworks for the ethical development and management of GenAI within health care settings.

Data Sources.—

The analysis draws from scientific journals, organizational websites, and recent guidelines on artificial intelligence ethics and regulation.

Conclusions.—

The literature on the ethical management of artificial intelligence in medicine is extensive but is still in its nascent stages because of the evolving nature of the technology. Effective and ethical integration of GenAI requires robust processes and shared accountability among technology vendors, health care organizations, regulatory bodies, medical professionals, and professional societies. As the technology continues to develop, a multifaceted ecosystem of safety mechanisms and ethical oversight is crucial to maximize benefits and mitigate risks.
Therapeutic Effect of Thymoquinone on Melatonin, Ferritin, and Renal Function in Renal Ischemia/Reperfusion Injury in Rats
Authors: Bozkurt Ahmet Sarper , Görücü Yılmaz Şenay
Published: September 2024

Objective: Ischemia/reperfusion (I/R) injury is the period of tissue or organ damage that develops after the tissue's blood flow is restored. The extent of damage varies according to the severity of tissue and cell damage. Thymoquinone (TQ) has a wide therapeutic spectrum. The effect of thymoquinone on melatonin and ferritin in I/R can regulate renal function by combining these two mechanisms to improve damage. Therefore, the effect of thymoquinone on melatonin and ferritin levels in renal I/R as well as its regulatory role in renal functions have been investigated.
Methods: Thirty-six male Sprague Dawley rats were included in the study (250-300 g, 8-10 weeks). The rats were randomly assigned to 6 groups with 6 animals in each group. Groups; 1- Control, 2- Sham, 3- Solvent, 4- Renal ischemia/reperfusion injury (I/R), 5- I/R+ Thymoquinone (TQ) (5 mg/kg/day), 6- TQ (5 mg/kg/day). The dorsal region of the rats was surgically opened, and the left renal artery was clamped for 30 minutes and then reperfused for 24 hours. TQ (i.p) was applied to the treatment groups for 15 days. At the end of the experiment, blood samples were taken from all groups, and kidney function tests (Na+, K+, Creatinine, urea, BUN) were performed. Melatonin and ferritin levels were analyzed by the ELISA method from kidney tissue samples.
Results: Data showed that short-term TQ treatment was effective on serum K+ (P = 0.010) and melatonin and ferritin levels in kidney tissue. Melatonin and iron activity, which were normal in healthy groups, melatonin decreased and ferritin increased significantly in the I/R group. TQ treatment positively regulated the dysregulation of these two molecules in I/R.
Conclusion: TQ may contribute to the healing of the damage by improving the K+ levels, which indicates the insufficiency of kidney functions in I/R damage. Melatonin and ferritin, as interacting molecules in I/R, are regulated by TQ, indicating that they may contribute to the management of I/R damage.
Feeder–Line Concept Development For Public Transportation Network In Urban Area Based On O-D Matrix And Performance Evaluation
Authors: Hariani Mira Lestira , Karina Gitta , Fitriyanti Rika
Published: September 2024

The management of the public transport network system is very important because it affects the future of the city and supports the activities of the community in travelling and movement. This research aims to develop a feeder-line concept on the public transport network based on O-D Matrix and Operational Performance Evaluation. The research method used is the operational performance standard indicator approach based on the Directorate General of Land Transportation SK 687/AJ.206/DRJD/2002 and the O-D Matrix method in determining new route recommendations. This research uses secondary data as well as primary surveys to assess operational performance. The results show that the level of operational performance of public transport in the research area there are still several routes below the standard with a total of routes operating from D1 to D8 of which 75% of the routes are in good condition and the other 25% of the routes have substandard assessment results with a total value of ?18. Thus, it is recommended that rerouting to be carried out on routes whose operational performance is still below standard, namely routes D7, and D8 based on the characteristics of the feeder-line concept to BRT Corridor 2.
İç Anadolu Kurak Sahalarında Abiyotik Bitki Stresleri
Authors: Dönmez Abdullah Hüseyin , Yıldız Oktay
Published: September 2024

İç Anadolu kurak sahalarında bitki büyümesini etkileyen en önemli stres faktörleri kuraklık, sıcaklık, don, tuz ve bazı besin elementlerinin yararlanılabilir formlarının eksikliğidir. Bölge iklimsel olarak kurak olmasına rağmen mevsimsel kuraklıkta sık sık görülmektedir. Tuzlu topraklar bölge genelinde olmasa bile bazı taban arazilerde özellikle sodik toprak olarak sorun yaratmaktadır. Besin elementlerinden ise en çok fosforun yararlanılabilir formunun azlığı ile mikro besin elementlerinde demir, bakır ve çinko eksikliği öne çıkmaktadır. Bölgedeki ağaçlandırma çalışmalarının başarısı şimdiye kadar silvikültürel uygulamalarla açıklandığından bitki büyümesini sınırlayan çoğu mekanizma anlaşılamamıştır. Bu nedenle bitki büyümesini sınırlandıran ekolojik ve fizyolojik stres faktörlerini konu alan çalışmalar bölgedeki restorasyon çalışmalarının başarını arttırabilir.
Dentists, Their Handicraft Hobbies and City of London Livery Companies
Authors: Gelbier Stanley
Published: September 2024

Pierre Fauchard, considered the father of dentistry, contributed to the development of different fields of dentistry that we know today. However, the contribution of this important individual to the fields of oral medicine and oral and maxillofacial pathology is unknown. This study aimed to identify Pierre Fauchard’s contribution to these areas of dentistry. We focused on “Le Chirurgien Dentiste, or Traité des Dents” in both French and English, looking for information about the oral diseases diagnosed and treated by Fauchard. Information on patient history, disease description, treatment applied, and clinical follow-up was collected. A contemporary analysis of the diseases was performed, and the collected data were systematized, reported, and analyzed descriptively, according to the current literature on the addressed topics. Information on conditions such as scurvy, parulides, epulides, oral ulcers, entoalveolar abscesses, dental alterations, and post-exodontia incidents were elucidated. Findings indicated that Pierre Fauchard described, diagnosed, and treated different soft and hard tissue diseases of great interest to the fields of oral medicine and oral and maxillofacial pathology.
Kemajuan Uji Klinis Terdaftar Aktif pada Terapi Medikamentosa untuk Myasthenia Gravis 2024: Kajian Literatur
Authors: Setiawan Ahmad Haris
Published: September 2024

Myasthenia Gravis adalah proses autoimun yang bermanifestasi pada kelemahan otot dengan tingkatan beragam., mulai dari kelemahan otot mata hingga otot pernafasan. Berdasarkan patofisiologinya, pengobatan medikamentosa ditargetkan pada sel imun atau secara simptomatik. Lini pengobatan yang tersedia telah mencapai lini kelima dan terus berkembang. Kajian literatur ini bertujuan untuk menelaah perkembangan uji klinis yang sedang berjalan hingga Februari 2024. Jenis studi yang di gunakan literature review berdasarkan data registrasi uji klinis yang terdaftar aktif (fase 1 hingga 3) pada Clinicaltrial.gov dengan partisipan dewasa diikutsertakan dalam pengamatan. Terdapat 25 agen obat yang sedang diuji klinis dengan berbagai mekanisme aksi dan tujuan uji. Uji klinis yang sedang dilaksanakan tergolong beragam dan menunjukkan perkembangan yang baik untuk terapi myasthenia gravis.
Perbandingan Uji Kapasitas Total Antioksidan Ekstrak Daun Kelor dengan Metode DPPH, FRAP, dan ABTS
Authors: Putri Nawaika Shafira , Limanan David , Yulianti Eny , Ferdinal Frans
Published: September 2024

Reaksi oksidasi adalah proses alami dalam tubuh manusia yang terjadi selama metabolisme sel dan respirasi, menghasilkan reactive oxygen species (ROS) atau radikal bebas. Ketidakseimbangan antara produksi ROS yang berlebihan dan pertahanan antioksidan yang tidak memadai dapat menyebabkan stres oksidatif, yang berdampak negatif pada molekul biologis seperti karbohidrat, protein, lipid, dan DNA. Stres oksidatif ini berkontribusi pada berbagai penyakit, termasuk radang sendi, aterosklerosis, diabetes, kanker, dan gangguan neurodegeneratif, serta mempercepat penuaan. Antioksidan berperan penting dalam menetralkan radikal bebas dan memperbaiki kerusakan akibat stres oksidatif. Daun kelor (Moringa oleifera L) dikenal kaya akan nutrisi dan antioksidan, termasuk vitamin C, vitamin E, flavonoid dan tanin. Penelitian ini bertujuan untuk mengevaluasi kapasitas total antioksidan dari ekstrak daun kelor menggunakan tiga metode yang berbeda, yaitu DPPH (2,2-difenil-1-pikrilhidrazil), FRAP (Ferric Reducing Antioxidant Power), dan ABTS (2,2'-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid)). Pengukuran absorbansi dilakukan dengan menggunakan spektrofotometer Genesys 30-vis, dan data dianalisis menggunakan grafik dari program GraphPad Prism versi 7.0 (La Jolla, California, USA). Hasil penelitian menunjukkan bahwa nilai IC50 ekstrak daun kelor dengan metode DPPH adalah 71,011 μg/mL, yang tergolong antioksidan kuat (50-100 μg/mL). Dengan metode FRAP, nilai IC50 16,943 μg/mL, dengan metode ABTS nilai IC50 sebesar 25,533 μg/mL; keduanya termasuk dalam kategori antioksidan sangat kuat (<50 μg/mL). Hasil ini menunjukkan bahwa metode FRAP dan ABTS lebih sensitif dalam mendeteksi kapasitas antioksidan ekstrak daun kelor dibandingkan metode DPPH. Penelitian ini menunjukkan potensi ekstrak daun kelor sebagai sumber antioksidan alami yang berpotensi mencegah penyakit terkait stres oksidatif.
Pengaruh Kualitas Pelayanan, Infrastruktur Teknologi Informasi, dan Ketersediaan Tenaga Medis Terhadap Kepuasan Pasien di Rumah Sakit Swasta
Authors: Salendra Tania , Suciningtias Marlyn , Tandy Fenia , Bernarto Innocentius
Published: September 2024

Menurut Undang-Undang Kesehatan, kesehatan adalah hak asasi manusia dan merupakan salah satu elemen penting dalam kesejahteraan. Rumah sakit sebagai penyedia layanan kesehatan harus mengambil berbagai langkah untuk meningkatkan kepuasan pasien. Penelitian ini bertujuan untuk menganalisis dampak kualitas pelayanan, infrastruktur teknologi informasi dan ketersediaan tenaga medis terhadap kepuasan pasien di rumah sakit swasta. Metode yang digunakan adalah kuantitatif dengan pendekatan deskriptif. Data dikumpulkan melalui kuesioner yang disebarkan menggunakan Google Form. Populasi penelitian adalah seluruh anggota keluarga pasien di rumah sakit X, dengan teknik pengambilan sampel non-probability samplingyang kemudian menghasilkan 187 sampel. Hasil penelitian menunjukkan bahwa kualitas pelayanan, infrastruktur teknologi informasi dan ketersediaan tenaga medis berpengaruh positif terhadap kepuasan pasien. Oleh karena itu, rumah sakit swasta perlu memperhatikan faktor-faktor ini untuk meningkatkan kepuasan pasien.
Studi Eksperimen: Pengaruh Penggunaan Telur Pada Cookies Berbasis Pisang Kepok (Musa Paradisiaca L) Dan Kacang Merah (Phaseolus Vulgaris L.)
Authors: Cahya Aloysius Prima , Amara Diza
Published: September 2024

Penelitian ini bertujuan untuk mengevaluasi pengaruh penggunaan telur pada cookies berbasis tepung pisang kepok (Musa paradisiaca L.) dan tepung kacang merah (Phaseolus vulgaris L.) terhadap kandungan gizi dan daya terima. Penelitian ini menggunakan metode eksperimental dengan Rancangan Acak Lengkap (RAL) yang melibatkan dua faktor, yaitu tepung pisang kepok dan tepung kacang merah, dengan empat perlakuan: 100% tepung terigu sebagai kontrol, serta rasio tepung pisang kepok dan tepung kacang merah sebesar 75:25%, 85:15%, dan 95:5%. Hasil penelitian menunjukkan bahwa variasi penggunaan tepung pisang kepok dan tepung kacang merah mempengaruhi kandungan karbohidrat, protein, lemak, serat kasar, kadar air, dan kadar abu dalam cookies. Selain itu, pengujian organoleptik mengindikasikan bahwa formula dengan rasio 75:25% memiliki daya terima terbaik berdasarkan warna, tekstur, aroma, rasa, dan keseluruhan. Cookies berbasis pisang kepok dan kacang merah ini diusulkan sebagai alternatif pangan bagi penderita diabetes melitus tipe 2.
Kompres Dingin (Aloe Vera) dan Pijat Oksitosin Untuk Memperlancar Produksi ASI Pada Ibu Nifas di Puskesmas Rakit 1
Authors: Islamiati Shinta , Dewi Feti Kumala , Surtiningsih Surtiningsih
Published: September 2024

Banyaknya kasus pada masa nifas salah satunya yang sering dijumpai yaitu permasalahan dalam pemberian ASI yang disebabkan bendungan ASI karena adanya penyempitan duktus laktiferi oleh kelenjar-kelenjar yang tidak dikosongkan dengan sempurna sehingga menyebabkan ASI kurang lancar, oleh karena itu untuk mengatasi pengeluaran ASI kurang lancar dapat dilakukan dengan penerapan kombinasi kompres dingin aloe vera dan pijat oksitosin. Penelitian ini bertujuan untuk mengevaluasi efektivitas kombinasi kompres dingin dengan gel aloe vera dan pijat oksitosin dalam memperlancar produksi ASI pada ibu nifas di Puskesmas Rakit 1. Latar belakang penelitian ini adalah tingginya angka ibu nifas yang mengalami bendungan ASI, yang dapat menghambat pemberian ASI eksklusif dan meningkatkan risiko komplikasi seperti mastitis. Metode penelitian melibatkan lima responden ibu post partum yang mengalami produksi ASI kurang lancar dan nyeri payudara. Kombinasi terapi diterapkan selama empat hari, dengan kompres dingin aloe vera selama 10-15 menit dan pijat oksitosin selama 15-20 menit, dua kali sehari. Hasil penelitian menunjukkan penurunan skala nyeri dari tingkat sedang menjadi tidak nyeri pada semua responden, serta peningkatan volume ASI dari rata-rata 0,4 ml menjadi 9 ml setelah terapi. Temuan ini menunjukkan bahwa kombinasi kompres dingin aloe vera dan pijat oksitosin efektif dalam mengatasi masalah produksi ASI dan nyeri payudara pada ibu nifas. Penelitian ini memberikan solusi nonfarmakologis yang dapat diimplementasikan di fasilitas kesehatan untuk mendukung ibu menyusui.
Hubungan Antara Usia Dan Lama Penggunaan Ventilasi Mekanik Dengan Kejadian Vap (Ventilator Associated Pneumoniae) Pada Pasien di Ruang Icu Rumah Sakit Khusus Paru Karawang
Authors: Sutoyo Dede , Ria Roma Tao Toba Muara , Paturohman Asep
Published: September 2024

Ventilator Associated Pneumonia (VAP) adalah infeksi pneumonia yang sering terjadi terkait dengan layanan kesehatan, khususnya di Intensive Care Unit (ICU). Penelitian ini bertujuan untuk mengidentifikasi hubungan antara usia dan lama pemakaian ventilasi mekanik dengan kejadian VAP pada pasien di ICU Rumah Sakit Khusus Paru Karawang, dengan menggunakan alat ukur CPIS. Metode penelitian ini bersifat observasional untuk menganalisis hubungan antara paparan dan penyakit. Sampel yang diteliti sebanyak 40 orang melalui teknik non probability sampling. Data dianalisis secara deskriptif dan diuji menggunakan analisis bivariat (spearman rank) serta univariat. Hasil penelitian menunjukkan bahwa 55% responden yang mengalami VAP adalah lansia. Selain itu, ditemukan hubungan yang cukup kuat antara usia dan durasi penggunaan ventilasi dengan kejadian VAP, dengan nilai P Value masing-masing 0,01 dan 0,027. Penelitian ini menyimpulkan bahwa usia dan durasi penggunaan ventilasi mekanik merupakan faktor penting yang berkontribusi terhadap kejadian VAP. Untuk mengurangi risiko VAP, disarankan agar ICU mengimplementasikan bundel pencegahan VAP secara ketat, mengurangi durasi penggunaan ventilator jika memungkinkan, dan meningkatkan pelatihan serta kepatuhan terhadap protokol yang ada.
Framed hyperstrip affine space distribution
Authors: Eliseeva N. A. , Popov Yu. I.
Published: September 2024

A rigged hyperstrip distribution is a special class of hyperstrips. The study of hyperstrips and their generalizations in spaces with various fun­damental groups is of great interest due to numerous applications in mathematics and physics. A special place is occupied by regular hyper­strips, for which the characteristic planes of families of principal tangent hyperplanes do not contain directions tangent to the base surface of the hyperstrip. In this work, we use E. Cartan’s method of external differen­tial forms and the group-theoretic method of G. F. Laptev.

In affine space, a hyperstrip distribution is considered, which at each point of the base surface is equipped with a tangent plane and a conjugate tangent line. The specification of the studied hyperstrip distribution in an affine space with respect to a 1st order reference and an existence theorem are given. The fields of affine normals of the 1st kind for Blaschke and Transon are constructed and the conditions for their coincidence are found. The definition of normal affine connection and normal centroaffine connection on the studied framed hyperstrip distribution is given.
On derivations of linear algebras of a special type
Authors: Sultanov A. Ya. , Monakhova O. A. , Bolotnikova O. V.
Published: September 2024

In this work, Lie algebras of differentiation of linear algebra, the op­eration of multiplication in which is defined using a linear form and two fixed elements of the main field are studied. In the first part of the work, a definition of differentiation of linear algebra is given, a system of linear homogeneous equations is obtained, which is satisfied by the components of arbitrary differentiation. An embedding of the Lie algebra of differenti­ations into the Lie algebra of square matrices of order n over the field P is constructed. This made it possible to give an upper bound for the dimen­sion of the Lie algebra of derivations. It has been proven that the dimen­sion of the algebra of differentiation of the algebras under study is equal to n2 – n, where n is the dimension of the algebra. Next we give a result on the maximum dimension of the Lie algebra of derivations of a linear alge­bra with identity. Based on the above facts, it is proven that the algebras under study cannot have a unit.
Landscape – Soundscape – Waterscape : Concept for an inter- and transdisciplinary framework for regional integrated water and land management and the water-, energy- and food security nexus
Authors: Bogárdi János J. , Mizsei Zoltán , Tóth Gergely
Published: September 2024

This paper argues that integrated resource management (both stocks and fluxes) must be embedded into a transdisciplinary context. Preliminary, yet essential debates, plans and formulation of aspirations need to be formulated with the active participation of legitimate stakeholders and affected citizens. This implies, that next to the key integration of land- and water resources management voices articulating local needs, expressing and protecting cultural values and social preferences are to be heard and understood. The context of Landscape-Soundscape-Waterscape is recommended to serve as a conceptual model of dialogues to set consensus-based objectives and constraints for the detailed professional elaboration of development, restauration and protection plans for water-dominated landscapes and resource use. This multi-dimensional dialogue is even more important when several sectoral concerns are to be taken into a so called nexus consideration. The trans- and interdisciplinary model framework of Landscape-Soundscape-Waterscape is proposed to be tested first in case studies where the spatial extent of most of the resource use and protection interactions correspond with the living space (or homescape) used, intimately known and loved by those whose “sounds” should be captured and considered for the sake of sustainable future.
THE CHALLENGES OF COMMUNITY-BASED EDUCATION IN CREATING INCLUSIVE EDUCATION FOR MARGINALIZED GROUPS. A CASE STUDY OF MASJID TERMINAL SCHOOL, DEPOK CITY
Authors: Ulpah Mariam , Windiana Wiwin , Junejo Safiullah
Published: September 2024

The MASTER School (terminal mosque) is a free school founded by community representatives focusing on inclusive schools for marginalized people from low-income families in the Depok area, West Java. This school is considered to support the government's strategic plan to provide education for all. However, realizing the lack of the government's role in equalizing access to education, this paper attempts to answer the question: What factors are initiatives for MASTER schools to consider when developing inclusive education for marginalized groups through community-based education? How does MASTER school develop inclusive education for marginalized groups through community-based education? The method in this research is qualitative with a case study approach. The data was collected from interviews and observations of schools and classes, as well as from relevant journals and articles, sist research analysis. The findings of this paper show that several factors contributed to the establishment of the MASTER school, including social awareness, which is generated by self-designed school founders motivated by the surrounding social environment. In addition, the inclusive education implemented at the MASTER school is based on a narrow understanding of the differences between children in the same room and pro. It provides education without the support of adequate facilities and teachers. In addition, there still needs to be more understanding of educational inclusion, which is also a challenge for its implementation.
Masacre en Aguanueva
Authors:   Atarraya
Published: September 2024

Invasión, impunidad y guerrilla al sur de Saltillo por

Gilberto Sebastián Sánchez Luna

Aguanueva, al sur de Saltillo, era una de las haciendas que integraban el latifundio de la familia Sánchez Navarro que, en enero de 1847, fue escenario de uno de los actos de violencia colectiva hacia una población civil desarmada en la guerra México-Estados Unidos.
A mobile recording system featuring high-precision time synchronization
Authors: Sone Takuro , Maeda Takehiro , Kitani Tomoya
Published: September 2024

In mobile environments where recording devices and subjects are in motion, integrating data collected from multiple devices requires precise location and time information. Given that high-precision satellite positioning technology provides centimeter-level accuracy and that movement speeds in mobile environments are around several 10 m/s, the required time accuracy is under 1 millisecond. However, achieving this time accuracy with commonly used devices is not typically feasible.
This paper describes a basic architecture to realize time synchronization with less than one millisecond error with an independent recorder using high-precision timing pulses (1-PPS signal) output by a GNSS receiver. Next, we propose a method to precisely identify the image capture time using an optical beacon combining multiple point light sources called GNSS Clock Beacon (GCB). The time of image capture can be determined from GCB images with an accuracy less than or equal to the exposure duration. Finally, we describe an example implementation of a mobile recording system that can be mounted on a motorcycle, which can record time-synchronized data and video with high accuracy using multiple data loggers and video equipment.