bluuebunny/crossref_metadata_2025 huggingface dataset:
Unlocking the potential of biosynthesized zinc oxide nanoparticles for degradation of synthetic organic dyes as wastewater pollutants
Authors: Gangwar Jaya , Sebastian Joseph Kadanthottu
Published: September 2021

The azo dyes released into water from different industries are accumulating in the water bodies and bioaccumulating within living systems thereby affecting environmental health. This is a major concern in developing countries where stringent regulations are not followed for the discharge of industrial waste into water bodies. This has led to the accumulation of various pollutants including dyes. As these developing countries also face acute water shortages and due to the lack of cost-effective systems to remove these pollutants, it is essential to remove these toxic dyes from water bodies, eradicate dyes, or generate fewer toxic derivatives. The photocatalysis mechanism of degradation of azo dyes has gained importance due to its eco-friendly and non-toxic roles in the environment. The zinc nanoparticles act as photocatalysts in combination with plant extracts. Plant-based nanoparticles over the years have shown the potential to degrade dyes efficiently. This is carried out by adjusting the dye and nanoparticle concentrations and combinations of nanoparticles. Our review article considers increasing the efficiency of degradation of dyes using zinc oxide (ZnO) nanoparticles and understanding the photocatalytic mechanisms in the degradation of dyes and the toxic effects of these dyes and nanoparticles in different tropic levels.
Elaboration of pâté using fish residues
Authors: Matiucci Marcos Antonio , Chambo Ana Paula Sartório , Mikcha Jane Martha Graton , Réia Suzana Maria da Silva , Vitorino Kelly Cristina , Moura Lorena Batista de , Feihrmann Andresa Carla , Souza Maria Luiza Rodrigues de
Published: September 2021

Knowing the potential of fish waste for the preparation of pâtés, there is the possibility of adding greater sustainability to the aquaculture sector. The aim was to prepare pâtés from fish processing residues with the inclusion of smoked fishmeal and evaluate their sensory, microbiological, physicochemical, and shelf-life characteristics. Three treatments were used: pâté without fishmeal inclusion (PSF), with smoked salmon carcass meal inclusion (PFSD), and smoked tilapia carcass meal (PFTD). The inclusion of the flours reduced the moisture, carbohydrate, and water activity. However, they increased the ash, salt, and collagen content. The lipid content was higher for the PFSD. The PSF showed peak oxidation at 15 days and the PFSD and PFTD around 45 days over the course of the 90-day shelf-life. The luminosity and b* coordinate were lower for PFTD, while the a* coordinate was higher for PFSD. Only the b* coordinate showed changes in PSF and PFSD throughout the 30 days of shelf-life, and its color tended to yellow at 15 days. The sensory analysis did not differ statistically between treatments (p > 0.05) for all attributes, except color, where the highest score was attributed to PSF. As for the overall impression, PSF also obtained the highest score, which may be associated with its color. By including fish flours, the nutritional composition and color of the tilapia-trimmed pâtés are changed, achieving an average acceptance level of 67%.
Experimental study of amniotic membrane or topical propolis on induced cutaneous wound healing in Wistar rats
Authors: Reis Rafaela Eduarda dos , Rueda Letícia da Silva , Tuani Bruno Roberto Vidal , Repetti Cláudia Sampaio Fonseca , Porto Camila Dias , Teixeira Daniel de Bortoli
Published: September 2021

The study of propolis and the amniotic membrane as alternatives to promote the acceleration of healing has grown considerably. These products have shown to be easy to use, have bactericidal or bacteriostatic action and are affordable. The objective of the present study was to evaluate the action of the amniotic membrane of bitches and propolis in the healing of surgical wounds. To evaluate the efficacy of these methods the time for conclusion of the healing process of both groups was compared with a control group. In addition, the inflammatory response of each group was also evaluated to identify which alternative method could induce a better response in the healing process compared to the control group. For this purpose, 27 animals, Rattus norvegicus, variety Wistar, were used. Rats were separated into 3 groups with 9 animals each. Group I represented the 25% alcoholic propolis solution; Group II, Amniotic membrane; Group III was Control group. Wounds were assessed macroscopically for the lesion area, and microscopically for the histological quality of each wound layer and the intensity of inflammation and collagen deposition. After the macroscopic analysis, it was observed that there were no statistical differences among the 3 groups (p> 0.05) relevant to accelerate the healing process in terms of presence of inflammatory cells, fibroblasts, collagen, neovascularization, granulation tissue and re-epithelialization.
Mimicking LysC Proteolysis by ‘Arginine Modification-cum-Trypsin
Digestion’: Comparison of Bottom-up & Middle-down Proteomic
Approaches by ESI Q-TOF MS
Authors: Pandeswari P. Boomathi , Chary R. Nagarjuna , Kamalanathan A.S. , Prabhakar Sripadi , Sabareesh Varatharajan
Published: September 2021

Background:

Middle-down (MD) proteomics is an emerging approach for reliable identification
of post-translational modifications and isoforms, as this approach focuses on proteolytic
peptides containing > 25-30 amino acid residues (a.a.r.), which are longer than typical tryptic peptides.
Such longer peptides can be obtained by AspN, GluC, and LysC proteases. Additionally,
some special proteases were developed specifically to effect MD approach, e.g., OmpT, Sap9, etc.
However, these proteases are expensive. Herein we report a cost-effective strategy ‘arginine modification-
cum trypsin digestion’, which can produce longer tryptic peptides resembling LysC peptides
derived from proteins.

Objective::

The aim of this study is to obtain proteolytic peptides that resemble LysC peptides by using
'trypsin', which is a less expensive protease.

Methods:

This strategy is based on the simple principle that trypsin cannot act at the C-termini of
those arginines in proteins, whose sidechain guanidine groups are modified by 1,2-cyclohexanedione
or phenylglyoxal.

Results:

As a proof of concept, we demonstrate this strategy on four models: β-casein (bovine), β-
lactoglobulin (bovine), ovalbumin (chick) and transferrin (human), by electrospray ionization-mass
spectrometry (ESI-MS) involving hybrid quadrupole time-of-flight. From the ESI-MS of these
models, we obtained several arginine modified tryptic peptides, whose lengths are in the range of
30-60 a.a.r. The collision induced dissociation MS/MS characteristics of some of the arginine modified
longer tryptic peptides are compared with the unmodified standard tryptic peptides.

Conclusion:

The strategy demonstrated herein this proof-of-concept study is not only useful to obtain
longer tryptic peptides that mimic LysC proteolytic peptides, but also facilitates in enhancing
the probability of missed cleavages by the trypsin. Hence, this method aids in evading the possibility
of obtaining very short peptides that are <5-10 a.a.r. Therefore, this is indeed a cost-effective alternative/
substitute for LysC proteolysis and, in turn, for those MD proteomic studies that utilize
LysC. Additionally, this methodology can be fruitful for mass spectrometry-based de novo protein
and peptide sequencing.
The Janus-like Association between Proton Pump Inhibitors and Dementia
Authors: Papazoglou Anna , Arshaad Muhammad I. , Henseler Christina , Daubner Johanna , Broich Karl , Haenisch Britta , Weiergräber Marco
Published: September 2021

Early pharmacoepidemiological studies suggested that Proton Pump Inhibitors (PPIs) might increase the risk of Alzheimer’s Disease (AD) and non-AD related dementias. These findings were supported by preclinical studies, specifically stressing the proamyloidogenic and indirect anticholinergic effects of PPIs. However, further large-scale pharmacoepidemiological studies showed inconsistent results on the association between PPIs and dementia. Pharmacodynamically, these findings might be related to the LXR/RXR-mediated amyloid clearance effect and anti-inflammatory action of PPIs. Further aspects that influence PPI effects on AD are related to patient- specific pharmacokinetic and pharmacogenomic characteristics. In conclusion, a personalized (individualized) medicinal approach is necessary to model and predict the potential harmful or beneficial effects of PPIs in AD and non-AD-related dementias in the future.
Design, Synthesis, and Docking Studies of Thioimidazolyl Diketoacid
Derivatives Targeting HIV-1 Integrase
Authors: Zarghi Afshin , Karimi Nafiseh , Roudsari Rouhollah Vahabpour , Hajimahdi Zahra
Published: September 2021

Background:

Integrase enzyme is a validated drug target to discover novel structures as
anti-HIV-1 agents.

Objective:

This study aimed at developing a novel series of thioimidazolyl diketoacid derivatives
characterizing various substituents at N-1 and 2-thio positions of the central ring as HIV-1integrase
inhibitors.

Methods:

In this study, eighteen novel thioimidazolyl DKA derivatives were synthesized in a fivestep
parallel procedure and tested in vitro for the inhibition of both IN ST reaction and the singlecycle
HIV-1 replication in HeLa cell culture.

Results:

The obtained molecules were evaluated using the enzyme assay, displaying promising integrase
inhibitory activity with IC50 values ranging from 0.9 to 7.7 mM. The synthesized compounds
were also tested for antiviral activity and cytotoxicity using HeLa cells infected by the single-cycle
replicable HIV-1 NL4-3.

Conclusion:

The most potent compound was found to be 18i with EC50 = 19 μM, IC50 = 0.9 μM,
and SI = 10.5. Docking studies indicated that the binding mode of the active molecule is well aligned
with the known HIV-1integrase inhibitor.
Recent Patents on Preparation Methods and Mechanical Stability of Superhydrophobic Surface
Authors: Li Zhaolong , Liu Yingtao
Published: September 2021

Background:

Superhydrophobic surfaces have unique wettability and have shown
broad application prospects in many fields, such as self-cleaning and lubrication drag reduction.
However, the superhydrophobic surfaces are severely restricted by their poor mechanical stability
in practical application, and the mechanical stability of the superhydrophobic surface is always
affected by different preparation methods. Therefore, people pay more attention to the preparation
methods of superhydrophobic surfaces.

Objective:

The study aims to improve the mechanical stability of the superhydrophobic surface
and expand the application fields of the superhydrophobic surfaces; preparation methods of the
superhydrophobic surface have been continuously improved.

Methods:

This paper reviews various representative patents and papers on preparation methods of
the superhydrophobic surface at home and abroad.

Results:

In this review, the basic methods of preparing superhydrophobic surfaces were introduced,
and three typical methods were summarized, such as etching method, coating method, and
sol-gel method, then their advantages and disadvantages were discussed. In combination with the
latest research progress, it is proposed that the use of environmentally friendly low surface energy
modifiers and the use of the one-step method to prepare superhydrophobic surfaces are the future
development trends. Aiming at the problem of the mechanical stability of superhydrophobic surfaces,
the instability mechanism and stability evaluation methods of superhydrophobic surfaces
under mechanical action are reviewed, and three basic methods to improve the mechanical stability
of superhydrophobic surfaces are proposed.

Conclusion:

The optimization of the preparation method of the superhydrophobic surface is beneficial
to improve the mechanical stability of the superhydrophobic surface and expand the application
prospect of the superhydrophobic surfaces in various fields. More patents and papers on the
superhydrophobic surface will be invented later.
Evaluation of Erectile Dysfunction in Nonobese, Nondiabetic Men with Obstructive Sleep Apnea
Authors: Scoralick Ana Carolina D. , Júnior Alonço da C. Viana , Cavalcanti André L. , dos Santos Ana Paula C. , Neves Denise D. , Melo Maria Helena A.
Published: September 2021

Background:

Erectile Dysfunction (ED) has affected people suffering from Obstructive Sleep Apnea Syndrome (OSAS) and multiple studies have confirmed this correlation.

Objective:

The objective of the is to identify the association between ED and Obstructive Sleep Apnea (OSA) in nonobese, nondiabetic men based on the International Index of Erectile Function (IIEF).

Methods:

This retrospective cross-sectional study included 143 nonobese, nondiabetic men with OSA (age, ≥20 years) who visited the Sleep Outpatient Clinic of the Otorhinolaryngology Department at Hospital Naval Marcílio Dias from May 2017 to August 2018. Patient age, body mass index (BMI), drinking, smoking, laboratory diagnosis of hypogonadism based on total testosterone levels, and sleep parameters (e.g., apnea–hypopnea index, rapid eye movement density, and minimum Oxygen Saturation [SatO2]) were considered. Analysis of variance was used to evaluate means. The chi-squared test and Fisher’s exact test were used to compare variables and Person’s correlation coefficient was used to analyze numerical variables.

Results:

The mean minimum SatO2 was 78.89%, and 46% of patients exhibited minimum SatO2 <80%. Moreover, minimum SatO2 of <80% and increasing age were associated with ED complaints based on IIEF scores,. A laboratory diagnosis of hypogonadism was associated with increased BMI, and aging was associated with SatO2.

Conclusion:

The results of the study revealed that oxygen desaturation of <80% was related to complaints of ED from the IIEF. Moreover, a relationship between laboratory hypogonadism and increased BMI values, aging, and oxygen desaturation has been demonstrated. Therefore, we recommend polysomnography in patients with ED complaints.
The Effect of Simulation-based Training on Athletic Performances among Female Basketball Players
Authors: Javanmardi Zahra , Jahromi Maryam K. , Hemmatinafar Mohammad , Knechtle Beat , Nikolaidis Pantelis T.
Published: September 2021

Background:

The effectiveness of simulation-based training has been examined in various sports. However, considering the effect of gender and sport on training, it would be interesting to evaluate simulation-based training in female basketball.

Objective:

The purpose of the study was to examine the effect of simulation-based training on physical fitness and performance indices in female basketball players.

Methods:

Sixteen female semi-professional basketball players were randomly assigned to experimental (n=8; age, 25±2 years; weight, 62±9 kg; height, 167±8 cm) or control (n=8; age, 24±1 years; weight, 57±9 kg; height, 170±8 cm) groups. The experimental group participated in a six week basketball simulation training program including running with different speeds (jogging to sprinting), agility, jumping, and shuffling. Both groups performed the Cooper 12 min run, line drill, an adjusted T-test, 20 ms print, the Sargent vertical jump and basketball exercise simulation test before and after six weeks of the study period. Control and experimental groups performed typical basketball training, three times weekly. The overall training volume was similar for both groups.

Results:

The perceived exertion was higher in the simulation-based training than control (p<0.05) group. The findings of this study indicated a significant increase in VO2 max (p=0.001), anaerobic power (p=0.009), explosive leg strength (p=0.036), and total distance covered in basketball exercise simulation test (p=0.001) and decrease of the meantime of one round of basketball exercise simulation test (p=0.001) in the simulation training compared to the control group.

Conclusion:

Generally incorporation of the simulation-based training in conditioning programs is recommended for improving aerobic, anaerobic and leg explosive strength of basketball players.
FACTORS AFFECTING ANXIETY OF MOTHERS WITH LOW-BIRTH-WEIGHT BABIES IN SOUTHWEST SUMBA DISTRICT, EAST NUSA TENGGARA PROVINCE
Authors: Ndapa Conchita
Published: September 2021

The World Health Organization (WHO) states that 60-80% of the infant mortality rate (IMR) occurs due to low birth weight. Low Birth Weight (LBW) contributes 60% -80% of neonatal mortality. The Indonesian Health Demographic Survey (IDHS) in 2017 showed that the incidence of LBW in Indonesia reached 6.2% with a fairly high prevalence. These various effects of LBW are what then causes babies to often require intensive care in the hospital. This condition can then lead to anxiety in parents. Therefore, this study was conducted to determine the factors that influence anxiety in mothers who have babies with LBW conditions in Southwest Sumba Regency. This research was conducted on 20-26 March 2021 with a qualitative approach through interviews and measuring anxiety levels using the HARS questionnaire. The study population was all mothers who had LBW babies in Southwest Sumba. The research subjects were 6 respondents who were selected through the purposive sampling technique. The results showed that there were several factors that influenced the anxiety of mothers with LBW babies, including the mother's age at pregnancy, the amount of parity, and education.
As mulheres da EJA
Authors: Lima Francisca vieira , Wiese Andreia Faxina , Haracemiv Sonia Maria Chaves
Published: September 2021

A reflexão proposta neste artigo resulta de uma pesquisa realizada com mulheres, estudantes da EJA de um município do Paraná, tendo como objetivo compreender suas trajetórias escolares e identificar as dificuldades vivenciadas, os motivos para retornarem ao espaço escolar e o papel da educação em suas vidas. Para tanto, dentro de uma abordagem qualitativa, a metodologia utilizada foi a pesquisa documental e a história oral temática, organizadas e analisadas na perspectiva da análise de conteúdo de Bardin (2016). Os resultados demonstraram trajetórias permeadas por abandono escolar, dificuldades socioeconômicas e preconceitos e a educação como uma via para a conquista de um espaço na sociedade. Evidenciou-se a necessidade da escuta das vozes femininas, (re)conhecendo suas experiências de vida com vistas à elaboração de propostas pedagógicas humanizadoras e emancipadoras, considerando o contexto de exclusão ao qual, historicamente, essas estudantes foram submetidas.
O mundo do trabalho como espaço formativo feminino nas primeiras décadas do século XX
Authors: Campagnoli Karina Regalio
Published: September 2021

O objetivo deste artigo é refletir sobre algumas possibilidades de formação feminina durante as três primeiras décadas do século XX, por meio da gradativa inserção das mulheres no universo do trabalho remunerado fora do lar. Optou-se pela metodologia de pesquisa documental com análise qualitativa, investigando-se os arquivos do jornal Diário dos Campos, cuja sede encontra-se na cidade de Ponta Grossa – Paraná. Observou-se que, concomitantemente às profissões tradicionalmente compreendidas como adequadas para as mulheres, o gênero feminino também enfrentou os desafios de se inserir em ocupações mais arrojadas para elas neste contexto histórico. Conclui-se que o jornal Diário dos Campos promoveu a circulação de diversas notícias e reportagens que sinalizavam as oportunidades de formação feminina perpassadas pelo mundo do trabalho, possibilitando uma formação não somente profissional, mas também, social e humana.
Educação e formação de mulheres: a Revista Bem-Te-Vi na primeira metade do Século XX
Authors: Peres Cristiane Pereira , Furtado Alessandra Cristina Furtado
Published: September 2021

Este artigo analisa como a educação e a formação de mulheres foram pensadas em espaços para além da fé protestante, na primeira metade do século XX. Para isso, toma-se como fonte principal de pesquisa um impresso periódico protestante, revista Bem-te-vi, que circulou nesse período na Escola da Missão (Escola Primária General Rondon) na Reserva Indígena de Dourados (RID). Além do periódico, também analisa-se o jornal O Puritano. As fontes mobilizadas foram analisadas a partir dos pressupostos teóricos da História Cultural. O estudo dos conteúdos editados nas páginas da revista Bem-te-vi na primeira metade do século XX e direcionados à educação e à formação das mulheres, usados na Escola da Missão na RID, buscavam incutir padrões do universo feminino às meninas e mulheres indígenas, construídos e legitimados pela cultura ocidental. Constata-se, assim, que a Revista em análise, no período, constitui-se em um veículo de divulgação dos valores protestantes metodistas que ultrapassa os espaços de fé do protestantismo, que juntamente com o jornal O Puritano, permitiu compreender e refletir sobre os processos educativos e formativos de mulheres em espaços indígenas.
Therapeutic-resort rehabilitation of children with gallbladder pathology living in ecologically unfavorable territories of the Krasnodar Region
Authors: Nazaretyan V. G. , Shashel V. A. , Naumenko G. V. , Borovleva L. I.
Published: September 2021

Objective: To study the eff ectiveness of medical and preventive schemes of spa rehabilitation of children with biliary tract diseases living in ecologically unfavorable areas of the Krasnodar region.Materials and Methods: The study was conducted among children aged 7 to 14 years old burdened with gallbladder pathology (dysfunctional disorders of the biliary tract (DRBT)). In 2017-2020, the eff ectiveness of the therapeutic-resort stage of rehabilitation was studied in 127 children. The children permanently resided in Krasnodar and were admitted to the therapeutic spa-resort center of mother and child “Diluch” in the resort city of Anapa. The authors selected 93 (73.2%) children with hypofunctional gallbladder disorder (GI) and 34 (26.8%) children with hyperfunctional GI disorder for spa treatment. The control group included children with the 1st group of health. The eff ectiveness of the applied methods of rehabilitation was evaluated based on laboratory and instrumental studies, as well as periodic dynamic medical examinations, which included the collection of complaints, physical examination, and palpation of the abdominal cavity.Results: Therapeutic spa-rehabilitation of children with DRBT included balneotherapy, physiotherapy, and aerophytotherapy without the use of pharmacological drugs. At the same time, there was an improvement in the condition of both children with DRBT of the hypertensive type (94.1%) and among the subjects with DRBT of the hypotonic type (90.1). There were no cases of the condition worsening in the observed children with DRBT that permanently resided in unfavorable conditions of the Krasnodar Region.Conclusions: Based on the obtained results, it can be suggested that diff erentiated comprehensive rehabilitation in the conditions of the balneological complex of the resort city of Anapa performed aft er the main treatment of gastrointestinal pathology is feasible for children and adolescents experiencing adverse environmental impacts at a permanent place of residence in the Krasnodar region.
Comparative analysis of the genomic diversity of SARS-COV-2 circulating in the territories of the Rostov region and the republic of Crimea in the period from March to June 2021
Authors: Noskov A. K. , Podoynitsina O. A. , Vodopianov A. S. , Pisanov R. V. , Kovalev E. V. , Penkovskaya N. A. , Slis S. S. , Yanovich E. G. , Kuznetsova D. A. , Vodopianov S. O. , Chemisova O. S.
Published: September 2021

Objective: To compare the genomic diversity of SARS-CoV-2 strains that were spread in the Rostov region and the Republic of Crimea in the period from March to June 2021.Materials and Methods: A total of 194 samples were sequenced and 186 genovariants were recognized among them using the Pangolin program. Multiple alignment was performed and dendrograms were constructed for the samples belonging to the alpha and delta genovariants.Results: Changes of the predominant genovariants were revealed for territories of the Rostov Region and the Republic of Crimea from March to June. An increasing percent of the alpha variant was observed in both regions during the spring followed by the rapid emergence of the delta variant, which became predominant in June.Conclusion: It was shown that alpha variant samples from the Rostov region share a pool of common mutations, while in contrast, alpha variant samples from the Republic of Crimea are closer to those sampled from Moscow and Moscow region. At the end of May, the delta gene variant begins to be revealed, which is rapidly replacing other lines in all the territories considered in this study.
Score twice before you cut once: a clinical case of reconstructive bariatric surgery after obesity surgery in a patient with postoperative hypothyroidism and hypoparathyroidism
Authors: Volkova N. I. , Degtyareva Yu. S. , Burikov M. A.
Published: September 2021

Hundreds of thousands of bariatric surgeries are performed worldwide every year. Th ey have long been proven to be safe and eff ective in treating obesity and type 2 diabetes. Along with an unconditional positive eff ect, these interventions, especially shunting ones, are characterized by specifi c complications. In the absence of proper correction, they can become fatal for patients. One of these complications is malabsorption leading to a defi ciency of vitamins and microelements, which in most cases, is amenable to timely correction in the postoperative period. However, there are situations when it is not possible to carry out an eff ective correction and it becomes necessary to perform reconstructive interventions with the reverse inclusion of the small intestine in the digestion, which is associated with great diffi culties. Th e authors demonstrated this situation in the description of clinical observation of a patient with postoperative hypothyroidism and history of postoperative hypoparathyroidism, who underwent bariatric surgery. Impaired absorption of drugs (L-thyroxine, calcium, and vitamin D), and therefore, uncompensated hypothyroidism and hypocalcemia was an indication for reconstructive surgery.
Assessment of AAR and Sulfate Attack on Wadi Gravel Concrete after 4 Years in Service
Authors:   Infrastructure Research and Development (IRD QSTP-LLC), Doha, Qatar, Hassan Khaled , Sims Ian ,   RSK Environment Ltd, Hemel Hempstead, UK, Reid Murray ,   Infrastructure Research and Development (IRD QSTP-LLC), Glasgow, UK, Smith Alex ,   RSK Environment Ltd, Hemel Hempstead, UK, Al-Kuwari Mohammed ,   Ministry of Municipality and Environment, Doha, Qatar
Published: September 2021

Wadi gravel is a local aggregate in Qatar that could contribute to enhanced sustainability by replacing expensive imported gabbro. The material needs to be processed before use to reduce sulfate content to acceptable levels. The paper presents the performance assessment of three full-scale buildings, variously made with 50% and 100% Wadi gravel and conventional gabbro concretes. Site monitoring up to four years in service demonstrated the strength development with age and resistance to the aggressive exposure conditions in Qatar. The Wadi gravel concrete exhibited at least similar performance to the gabbro concrete, and excellent durability as defined in national construction specifications. The paper provides initial long-term assessment and builds on previous publications by the authors, for initial assessment of Wadi gravel concrete. In an earlier investigation by the authors, a difference was observed between the concrete prism expansion test results of RILEM AAR-4.1 and BS 812-123. Wadi gravel was classified as potentially reactive in the more accelerated RILEM AAR-4.1 and of low reactivity in the more realistic exposure BS 812-123. Petrographic examination of the hardened concrete after four years in service has shown no evidence of cracking or signs of distress or deterioration and confirmed the BS 812-123 interpretation of alkali-silica reactivity of Wadi gravel concrete. The results obtained in this investigation provide more confidence for the wider and efficient use of Wadi gravel in structural concrete.
The adoption of a Cyber Security Framework in a health care environment (Preprint)
Authors: Parmeggiani Domenico , Rinaldi Serena , Lanza Volpe Mariachiara , Nesta Giusiana , Ruggiero Roberto , Lucido Francesco Saverio , Parisi Simona , Gambardella Claudio , Serilli Francesca , Fisone Francesca , Docimo Ludovico
Published: September 2021

UNSTRUCTURED

As in any other fields, the healthcare industry is prone to cyber threats.
Every day, hospitals need to ensure that the informations about patients are adequately secure. Currently, CIOs and CISOs are trying to protect their departments from security matters. It is crucial to adopt appropriate measures to deal with risk management and business continuity. Focus of this paper is to review some of the common standards and frameworks used by healthcare organizations to face challenges of a Cyber Security.
Furthermore, we highlight advantages and disadvantages of information security standards as ISO/IEC 27799, HIPAA, HITRUST, NIST CSF and GDPR comparing with each other.
Co-created Mobile Apps for Palliative Care Using Community-Partnered Participatory Research: Development and Usability Study (Preprint)
Authors: Al-Mondhiry Jafar , D'Ambruoso Sarah , Pietras Christopher , Strouse Thomas , Benzeevi Dikla , Arevian Armen C , Wells Kenneth B
Published: September 2021

BACKGROUND

Open design formats for mobile apps help clinicians and stakeholders bring their needs to direct, co-creative solutions. Palliative care for patients with advanced cancers requires intensive monitoring and support and remains an area in high need for innovation.

OBJECTIVE

This study aims to use community-partnered participatory research to co-design and pretest a mobile app that focuses on palliative care priorities of clinicians and patients with advanced cancer.

METHODS

In-person and teleconference workshops were held with patient and family stakeholders, researchers, and clinicians in palliative care and oncology. Question prompts, written feedback, semistructured interviews, and facilitated group discussions identified the core palliative care needs. Using Chorus, a no-code app-building platform, a mobile app was co-designed with the stakeholders. A pretest with 11 patients was conducted, with semistructured interviews of clinician and patient users for feedback.

RESULTS

Key themes identified from the focus groups included needs for patient advocacy and encouragement, access to vetted information, patient-clinician communication support, and symptom management. The initial prototype, My Wellness App, contained a weekly wellness journal to track patient-reported symptoms, goals, and medication use; information on self-management of symptoms; community resources; and patient and caregiver testimonial videos. Initial pretesting identified value in app-based communication for clinicians, patients, and caregivers, with suggestions for improving user interface, feedback and presentation of symptom reports, and gamification and staff coordinators to support patient app engagement.

CONCLUSIONS

The development of a mobile app using community-partnered participatory research is a low-technology and feasible intervention for palliative care. Iterative redesign and user interface expertise may improve implementation.
Covid 19 pandemic: challenges, available and future global armoury (Preprint)
Authors: Mohapatra Sradhanjali , Kumar P Ayash , Farooq Uzma , khan Rahmuddin , Mirza Mohd Aamir , Iqbal Zeenat
Published: September 2021

BACKGROUND

The SARS‐CoV‐2 (COVID-19) outbreak is a major health crisis across the globe that caused significant distress and hence deteriorates the quality of life (QoL)of the individual. People try to maintain good physical health. However, mental affliction is still overlooked. Increase mortality and morbidity rate, loss of income, home-schooling and social isolation are few reasons responsible for declined health in varieties of populations.

OBJECTIVE

The objective of the present review is to raise mindfulness among readers toward the management of physical and mental health by catering adequate information about the symptoms, risk factors, protecting factors, accessible diagnosis technique, available medications and vaccines for COVID-19 health emergency together with investigational research that may be helpful to better deal with this calamity.

METHODS

A narrative review of all the relevant articles and reports were conducted with relevant keywords across different sources.

RESULTS

This review includes symptoms of declined physical health laterally with different accessible diagnostic techniques for COVID-19. Also contains the COVID-linked psychological agony in diverse population groups, its impact on the mind, with possible risk and protecting factors along with suggested solutions for maintaining good health. Additionally, it enlists available medications, vaccines and also some investigational research in the form of patents and clinical trials.

CONCLUSIONS

This article may act as a complete information sheet for COVID-19 related well-being accompanied by its management techniques with special emphasis on coping strategies for mental health, an ignored health segment. Further, it may assist the leaders and policy-makers to devise more novel and innovative policies that enable the public to overcome this pandemic-driven adversity not only in the present situation but also help to prepare for impending disasters.

CLINICALTRIAL

Not applicable
“Getting to Denmark" from Indonesia: Starting from State Institutions or Tax Capacity?
Authors: Iswahyudi Heru
Published: September 2021

Introduction/Main Objectives: This paper is aimed at answering the following research questions: Where should Indonesia’s journey toward a prosperous society start from? Should state institutions be improved first to increase the tax collection necessary to finance this journey? Or should the tax capacity be improved first to help improve the institutions? Background Problems: Maintaining good quality state institutions requires fiscal support and, vice versa, maintaining fiscal support through tax revenue requires the existence of good quality state institutions. This paper empirically examines which of these two aspects needs to be improved first to achieve a better society for Indonesians. Novelty: To the best of the author’s knowledge this paper may be the first that tries to empirically explore the causal relationships between the quality of Indonesia’s state institutions and its tax capacity. Research Methods: Answers to the research questions were approached by employing a vector error-correction model of governance indicators and tax revenue data for Indonesia, covering the period from 2002 to 2017. Finding / Results: It has been found that, for Indonesia, the quality of the state institutions and the tax capacity did not have a causal relationship in any direction. Conclusion: Indonesia seems to be caught in a dilemma: On one side, choosing the strategy of improving the quality of the institutions first may not be sustainable because it is unlikely to lead to improvements in the tax capacity, thus the prospects for sustaining good-quality institutions may be uncertain due to the possible lack of fiscal support. On the other hand, improving the tax capacity first does not seem to be a reliable strategy either because it may not result in better quality state institutions, hence revenue mobilization efforts might not be effective due to the incomplete support provided by the poor-quality institutions
Exploring the Existence of Innovative Work Behavior among Government Employee: Have Been There?
Authors: Kurniawan Dediek Tri , Kusnayain Yesiana Ihda , Aulisaina Fatwah Inna , Hakim Muhamad Arif Rahman
Published: September 2021

Introduction/Main Objectives: This study aims to determine the existence of innovative work behavior ecosystems for Indonesia’s government employees Background problems: The quality of individual employees partially determines the quality of the organization. The abilities of the different employees who work in the same system will undoubtedly deliver the government employee and possibly produce results which are less than were expected. Novelty: The previous studies have examined innovative work behavior, focusing on the external factors and ignoring the internal factors of individual traits. This study focused on investigating the interrelationship among the factors that will be affected by innovative behavior, especially in government employees in Indonesia. Methods: This study examines the relationship among these variables using structural equation modeling (SEM) with LISREL 8.8 as the statistical tool. Finding/Result: This study found that transforma­tional leadership and work engagement positively influence innovative work behavior. Unexpectedly, this research indicates an insignificant relationship between organizational justice and innovative work behavior among government employees. Besides, this study also found that transformational leadership and organizational justice have an impact on work engagement. Conclusion: These findings provide managerial implications about the need to strengthen employees’ innovative work behavior to ensure the organization’s continuity. Additionally, the results prove that innovative work behavior by government employees is supported by government’s role such as the style of leadership and work engagement.
К АНАЛИЗУ СИНГУЛЯРНЫХ ЗОН МЕХАНИЗМОВ ПАРАЛЛЕЛЬНОЙ СТРУКТУРЫ С ЛИНЕЙНЫМИ ДВИГАТЕЛЯМИ
Authors: Гебель Е. , Гаврилина Л. , Глазунов В. , Ласточкин А. , Романов А. , Духов А.
Published: September 2021

Рассмотрены различные особые положения (сингулярности) механиз-
мов параллельной структуры с линейными двигателями, а также особое
(сингулярное) положение, при котором был смещен центр выходного
звена по сравнению с исходной конфигурацией. Проведено сравнение
кинематических и взаимных винтов, соответствующих различным осо-
бым положениям (сингулярностям).
Application of Industrial Engineering Techniques for Continuous Improvement in Plastic Industry
Authors: Pawar Shantanu
Published: September 2021

Abstract: Industrial engineering is a specified field of engineering that deals with the design, improvement, and installation of integrated systems such as of people, materials, and energy in industry. Industrial engineers use specialized knowledge and skills in the mathematical, physical and social sciences, together with the principles and methods of engineering analysis and design, to specify, predict, and evaluate the results obtained from systems and processes. As the present condition of the company is capable to some extent, but it is not sufficient as it looks. But it also faces some problems due to some improper arrangement like no proper storage system, proper material handling component, improper layout and improper arrangement of working tools. So to overcome these problems in the company, industrial engineering and its techniques can be used. By applying industrial engineering and its techniques there is improvement in companies existing situation and it helps to improve productivity and profit of the company. Problems identified in the company Atharva Moulds Pvt. Ltd. are storage department problem, company layout, material handling problem, 5s and safety issues. This problems are sort by using various engineering techniques such as, 5s, layout improvement, material handling, maintenance, safety, etc tools and productivity is improved. Keywords: Industrial Engineering, Productivity, Engineering Techniques,
ENTRE POBREZA Y VIOLENCIA: ¿CÓMO AFECTAN LOS ESTRESORES DIARIOS Y LA VIOLENCIA A ADOLESCENTES EN ZONAS DE GUERRA?
Authors: Mels Cindy
Published: September 2021

Se ha establecido científicamente que la violencia sufrida en situaciones de guerra afecta negativamente al funcionamiento psicológico de las víctimas, no obstante, se supone que es el conjunto de varios factores de riesgo y factores protectores los que determinan las reacciones concretas. Este artículo se enfocará en dos factores de riesgo –la exposición a eventos violentos y los estresores diarios– y su relación con conductas internalizadas (depresión y ansiedad) en adolescentes viviendo en una zona de guerra. A través de un muestreo por conglomerados comprendiendo 13 colegios en 4 zonas seleccionadas en Ituri, una provincia en el noreste de la República Democrática del Congo, se encuestan 991 alumnos (13 a 21 años) por medio de cuestionarios de auto-informe, revelando datos sobre las variables sexo, edad, exposición a la violencia, estresores diarios, conductas internalizadas y externalizadas. Se encontró que los adolescentes varones  resultaron más expuestos a la violencia que las adolescentes mujeres. La exposición a eventos violentos también se diferenció según la edad, en ambos sexos. A su vez, los adolescentes mayores, tanto varones como mujeres, reportaron más estresores diarios que sus pares de menor edad. Un efecto de interacción entre la exposición a la violencia y estresores diarios predijo comportamientos internalizados a medida que ambas variables se acumulaban. Además, las adolescentes mujeres, mostraron más conductas internalizadas bajo la acumulación de estresores diarios que los adolescentes varones. Concluimos que los estresores diarios están asociados con mayores niveles de conductas internalizadas, sobre todo en adolescentes mujeres, y que la exposición a la violencia aumenta el efecto. A pesar de la violencia sufrida, la reducción de estresores diarios en la vida de adolescentes afectados por la guerra, podría promover su resiliencia y minimizar en cierta medida los síntomas psicológicos causados por el estrés acumulado durante la guerra.
MANUAL DE PSICOÉTICA. ÉTICA PARA PSICÓLOGOS Y PSIQUIATRAS
Authors: França Tarragó Omar
Published: September 2021

Reseña a cargo del Prof. Dr. Omar França Tarragó. Director de la Cátedra de Éticas Aplicadas. Departamento de Formación Humanística.Universidad Católica del Uruguay
LA REGULACIÓN AFECTIVA EN LA CONFORMACIÓN DE LA PERSONALIDAD. Estudio en escolares de 5 a 8 años
Authors: Miller Delfina
Published: September 2021

Este trabajo profundiza, desde la perspectiva psicoanalítica, en la regulación afectiva y su incidencia en la organización de la personalidad,  a partir de una investigación tanto  conceptual como empírica. Se utilizó un diseño cuanti-cualitativo, sobre una muestra de 82 niños montevideanos, provenientes de tres medios socioeconómicos  diferentes (alto, medio, bajo), La media de edad fue 6,2 años, con una prevalencia del 64% de varones. En la muestra se evidenció una alta prevalencia (18,9%) de niños con  disregulación, provenientes en su mayoría del medio socioeconómico más carenciado (78,5%), de familias monoparentales y con antecedentes psiquiátricos.  Según este estudio, la disregulación se asocia a importantes alteraciones en el desarrollo  especialmente sueño, aprendizaje, adquisición de hábitos y empatía,  generando dificultades en todas las áreas de desarrollo. Los niños con disregulación afectiva evidencian muy escasos afectos positivos y prácticamente no muestran miedo ni tristeza, tanto en sus juegos como en sus reacciones psicofisiológicas.
PROPIEDADES PSICOMÉTRICAS DE UNA PRUEBA EXPERIMENTAL DE DICTADO DE PALABRAS PARA LA EVALUACIÓN DE LA ORTOGRAFÍA EN ESCOLARES URUGUAYOS
Authors: Cuadro Ariel , Costa Ball Daniel , Palombo Ana Laura , Von Hagen Alexa
Published: September 2021

Se presenta el desarrollo de una prueba de dictado de palabras (TEO-D) para la evaluación del nivel ortográfico de escolares de segundo a sexto grado de primaria, con el objetivo de contribuir a las prácticas educativas y a la valoración neuropsicológica y psicopedagógica de las dificultades en lenguaje escrito. La prueba se construyó a partir de la revisión y análisis de palabras frecuentes de nuestro medio, que contienen la alternancia del grafema b y v para representar el fonema /b/, los grafemas j y g para la representación del sonido /j/, las palabras, que pueden escribirse con ll o y, las que contienen el grafema h para el que no hay fonema y los grafemas c y s, que representan el sonido /s/. Se examina la estructura factorial, la fiabilidad y la validez de la prueba, que fue aplicada a una muestra de 488 alumnos de Montevideo, seleccionados mediante muestreo por conveniencia, entre dos colegios de educación privada de nivel socioeconómico medio bajo y medio alto. El  análisis factorial confirmatorio, utilizando el programa NOHARM  de un modelo de factor único, indica un ajuste adecuado a una estructura unidimensional, obteniendo una muy buena fiabilidad de consistencia interna en la muestra total y por curso.
ESTILOS PARENTALES, PARENTALIDAD POSITIVA Y FORMACIÓN DE PADRES
Authors: Capano Álvaro , Ubach Andrea
Published: September 2021

El presente trabajo surge como una inquietud de los autores, (integrantes de una ONG que se dedica al trabajo con niños y adolescentes que han sufrido la vulneración de algunos de sus derechos) por revisar en un rápido recorrido los desarrollos conceptuales que nos parecen más relevantes sobre los estilos educativos parentales y las posibles consecuencias del ejercicio de uno u otro en niños y/o adolescentes. Además, el trayecto realizado nos ha permitido reflexionar sobre  algunos conceptos, dejar planteadas algunas preguntas y pensar sobre concepciones educativas alternativas, para llegar a la conclusión en última instancia de la relevancia que adopta la formación de padres, no como una posibilidad remota y aislada, sino como un camino necesario a recorrer por instituciones educativas, sociales y sanitarias, públicas y privadas.
SLOGANS ON THE WORKS OF MASTERS OF CHINA'S INTANGIBLE CULTURAL HERITAGE AS A MEANS OF COMBATING THE EPIDEMIC OF CORONAVIRUS INFECTION (COVID-19)
Authors:   LI XIN Heihe Institute, XIN LI , STARODUBTSEVA NATALYA S. ,   NATALYA S. STARODUBTSEVA Amur State University
Published: September 2021

This study aims to identify the content and lexical patterns of slogans in the works of intangible cultural heritage masters devoted to one of the most popular topics - "Fighting the epidemic" (COVID-19). Continuous sampling method was used to select 538 slogans containing various appeals. Their analysis was performed using descriptive method, classification and systematization techniques. The study enabled to determine the frequency of the ways to raise people’s spirit during the epidemic and the particular means to fight it. Slogans containing calls on people for prevention and control, particular measure of hygiene and mode of social activity turned out the most frequent. They were followed by the appeals to unite efforts in the fight. The least frequent were slogans with political, emotional and value-culture content. All these patterns were manifested by the corresponding verbs (mostly in Imperative), nouns, adjectives and word groups.