bluuebunny/crossref_metadata_2025 huggingface dataset:
Vittrup Man–The life-history of a genetic foreigner in Neolithic Denmark
Authors: Fischer Anders , Sjögren Karl-Göran , Jensen Theis Zetner Trolle , Jørkov Marie Louise , Lysdahl Per , Vimala Tharsika , Refoyo-Martínez Alba , Scorrano Gabriele , Price T. Douglas , Gröcke Darren R. , Gotfredsen Anne Birgitte , Sørensen Lasse , Alexandersen Verner , Wåhlin Sidsel , Stenderup Jesper , Bennike Ole , Ingason Andrés , Iversen Rune , Sikora Martin , Racimo Fernando , Willerslev Eske , Allentoft Morten E. , Kristiansen Kristian
Published: February 2024

The lethally maltreated body of Vittrup Man was deposited in a Danish bog, probably as part of a ritualised sacrifice. It happened between c. 3300 and 3100 cal years BC, i.e., during the period of the local farming-based Funnel Beaker Culture. In terms of skull morphological features, he differs from the majority of the contemporaneous farmers found in Denmark, and associates with hunter-gatherers, who inhabited Scandinavia during the previous millennia. His skeletal remains were selected for transdisciplinary analysis to reveal his life-history in terms of a population historical perspective. We report the combined results of an integrated set of genetic, isotopic, physical anthropological and archaeological analytical approaches. Strontium signature suggests a foreign birthplace that could be in Norway or Sweden. In addition, enamel oxygen isotope values indicate that as a child he lived in a colder climate, i.e., to the north of the regions inhabited by farmers. Genomic data in fact demonstrates that he is closely related to Mesolithic humans known from Norway and Sweden. Moreover, dietary stable isotope analyses on enamel and bone collagen demonstrate a fisher-hunter way of life in his childhood and a diet typical of farmers later on. Such a variable life-history is also reflected by proteomic analysis of hardened organic deposits on his teeth, indicating the consumption of forager food (seal, whale and marine fish) as well as farmer food (sheep/goat). From a dietary isotopic transect of one of his teeth it is shown that his transfer between societies of foragers and farmers took place near to the end of his teenage years.
Co-design for stroke intervention development: Results of a scoping review
Authors: Singh Hardeep , Benn Natasha , Fung Agnes , Kokorelias Kristina M. , Martyniuk Julia , Nelson Michelle L. A. , Colquhoun Heather , Cameron Jill I. , Munce Sarah , Saragosa Marianne , Godhwani Kian , Khan Aleena , Yoo Paul Yejong , Kuluski Kerry
Published: February 2024

Background

Co-design methodology seeks to actively engage end-users in developing interventions. It is increasingly used to design stroke interventions; however, limited guidance exists, particularly with/for individuals with stroke who have diverse cognitive, physical and functional abilities. Thus, we describe 1) the extent of existing research that has used co-design for stroke intervention development and 2) how co-design has been used to develop stroke interventions among studies that explicitly used co-design, including the rationale, types of co-designed stroke interventions, participants involved, research methodologies/approaches, methods of incorporating end-users in the research, co-design limitations, challenges and potential strategies reported by researchers.

Materials and methods

A scoping review informed by Joanna Briggs Institute and Arksey & O’Malley methodology was conducted by searching nine databases on December 21, 2022, to locate English-language literature that used co-design to develop a stroke intervention. Additional data sources were identified through a hand search. Data sources were de-duplicated, and two research team members reviewed their titles, abstracts and full text to ensure they met the inclusion criteria. Data relating to the research objectives were extracted, analyzed, and reported numerically and descriptively.

Results

Data sources used co-design for stroke intervention development with (n = 89) and without (n = 139) explicitly using the term ‘co-design.’ Among studies explicitly using co-design, it was commonly used to understand end-user needs and generate new ideas. Many co-designed interventions were technology-based (65%), and 48% were for physical rehabilitation or activity-based. Co-design was commonly conducted with multiple participants (82%; e.g., individuals with stroke, family members/caregivers and clinicians) and used various methods to engage end-users, including focus groups and workshops. Limitations, challenges and potential strategies for recruitment, participant-engagement, contextual and logistical and ethics of co-designed interventions were described.

Conclusions

Given the increasing popularity of co-design as a methodology for developing stroke interventions internationally, these findings can inform future co-designed studies.
Single versus bilateral internal thoracic artery grafting in patients with impaired renal function
Authors: Farkash Ariel , Gordon Amit , Mohr Rephael , Sela Orr , Pevni Dmitri , Ziv-Baran Tomer , Grupper Ayelet , Kfir Jonathan E. , Ben-Gal Yanai
Published: February 2024

Objective

The optimal strategy for surgical revascularization in patients with impaired renal function is inconclusive. We compared early and late outcomes between bilateral internal thoracic artery (BITA) and single ITA (SITA) grafting in patients with renal dysfunction.

Methods

This is a retrospective analysis of all the patients with multivessel disease and impaired renal function (estimated glomerular filtration rate <60mL/min/1.73m2) who underwent isolated coronary artery bypass graft (CABG) in our center during 1996–2011, utilizing either BITA or SITA revascularization.

Results

Of the 5301 patients with multivessel disease who underwent surgical revascularization during the study period, 391 were with impaired renal function: 212 (54.2%) underwent BITA, 179 (45.8%) underwent SITA. Patients who underwent BITA were less likely to have comorbidities. Statistically significant differences were not observed between the BITA and SITA groups in 30-day mortality (5.6% vs. 9.0%, p = 0.2) and in rates of early stroke, myocardial infarction, and sternal infection (4.5% vs. 6.1%, p = 0.467; 1.7% vs. 2.8%, p = 0.517; and 2.2% vs. 5.7%, p = 0.088, respectively). Long-term survival of the BITA group was better: median 8.36 vs. 4.14 years, p<0.001. In multivariable analysis, BITA revascularization was associated with decreased late mortality (HR = 0.704, 95% CI: 0.556–0.89, p = 0.003). In analysis of a matched cohort (134 pairs), early outcomes did not differ between the groups; however, in multivariable analysis, BITA revascularization was associated with decreased late mortality ‎‎(HR = 0.35 (95%CI 0.18–0.68), p = 0.002)‎.

Conclusions

BITA revascularization did not impact early outcome in patients with CRF, but demonstrated a significant protective effect on long-term survival ‎in the unmatched and matched cohorts.
Using spatio-temporal graph neural networks to estimate fleet-wide photovoltaic performance degradation patterns
Authors: Fan Yangxin , Wieser Raymond , Yu Xuanji , Wu Yinghui , Bruckman Laura S. , French Roger H.
Published: February 2024

Accurate estimation of photovoltaic (PV) system performance is crucial for determining its feasibility as a power generation technology and financial asset. PV-based energy solutions offer a viable alternative to traditional energy resources due to their superior Levelized Cost of Energy (LCOE). A significant challenge in assessing the LCOE of PV systems lies in understanding the Performance Loss Rate (PLR) for large fleets of PV systems. Estimating the PLR of PV systems becomes increasingly important in the rapidly growing PV industry. Precise PLR estimation benefits PV users by providing real-time monitoring of PV module performance, while explainable PLR estimation assists PV manufacturers in studying and enhancing the performance of their products. However, traditional PLR estimation methods based on statistical models have notable drawbacks. Firstly, they require user knowledge and decision-making. Secondly, they fail to leverage spatial coherence for fleet-level analysis. Additionally, these methods inherently assume the linearity of degradation, which is not representative of real world degradation. To overcome these challenges, we propose a novel graph deep learning-based decomposition method called the Spatio-Temporal Graph Neural Network for fleet-level PLR estimation (PV-stGNN-PLR). PV-stGNN-PLR decomposes the power timeseries data into aging and fluctuation components, utilizing the aging component to estimate PLR. PV-stGNN-PLR exploits spatial and temporal coherence to derive PLR estimation for all systems in a fleet and imposes flatness and smoothness regularization in loss function to ensure the successful disentanglement between aging and fluctuation. We have evaluated PV-stGNN-PLR on three simulated PV datasets consisting of 100 inverters from 5 sites. Experimental results show that PV-stGNN-PLR obtains a reduction of 33.9% and 35.1% on average in Mean Absolute Percent Error (MAPE) and Euclidean Distance (ED) in PLR degradation pattern estimation compared to the state-of-the-art PLR estimation methods.
Effect of forward moment on recovery motion against tripping
Authors: Akiyama Yasuhiro , Nishizaki Aoto , Okamoto Shogo , Yamada Yoji
Published: February 2024

Investigating the fall recovery motion mechanism is crucial to prevent fall injuries. Among the various parameters of motion and posture, the forward moment can be considered the representative parameter of the magnitude of tripping from a kinematic perspective. The effect of increasing the forward moment on the recovery motion after tripping was investigated in this study. A tripping experiment was performed on a treadmill, and the recovery motion was observed. The forward moment was artificially increased using several approaches, such as pulling the torso, increasing gait speed, and increasing body mass. Factor analysis was performed to establish the relationship between the recovery motion parameters and forward moment. The distribution of the factor scores implied the uniqueness of the recovery motion of the pull condition. Although the forward moment temporarily increased, it was compensated quickly. The other conditions and factors indicated qualitative similarity of the recovery motion among the different conditions. This study demonstrates that the recovery motion after tripping is robust against an increase in forward moment, regardless of the method used to increase the forward moment. The investigation of reaction motion pattern enables validation of the recovery motion and falling posture estimation. Such fall simulations will facilitate the development of a method of fall prevention and mitigation.
Perioperative management of kidney transplantation in China: A national survey in 2021
Authors: Zhu Ziyu , Chi Xiaoying , Chen Yuwen , Ma Xiaowen , Tang Ying , Li Dawei , Zhang Ming , Su Diansan
Published: February 2024

Perioperative anaesthesia management has an important significance for kidney transplantation; however, the related consensus remains limited. An electronic survey with 44 questions was developed and sent to the chief anaesthesiologist at 115 non-military medical centres performing kidney transplantation in China through WeChat. A response rate of 81.7% was achieved from 94 of 115 non-military medical centres, where 94.4% of kidney transplants (10404 /11026) were completed in 2021. The result showed an overview of perioperative practice for kidney transplantations in China, identify the heterogeneity, and provide evidence for improving perioperative management of kidney transplantation. Some controversial therapy, such as hydroxyethyl starch, are still widely used, while some recommended methods are not widely available. More efforts on fluid management, hemodynamical monitoring, perioperative anaesthetics, and postoperative pain control are needed to improve the outcomes. Evidence-based guidelines for standardizing clinical practice are needed.
Study on nonlinear dynamic characteristics of a two-speed transmission system at low speed
Authors: Zhihui Liu , Zhang Jiahao , Zhang Zhijian , Gu Yingzhi , Wen Xue , Zhu Kejun
Published: February 2024

A pure shear mechanical model of low gear of six-degree-of-freedom two-speed transmission system is established by using lumped parameter method. The Runge-Kutta method is used to numerically solve the aforementioned nonlinear system. The variation of transmission error between gears is analyzed by using global bifurcation, time domain diagram, phase diagram and Poincare cross section. Moreover, the transfer error bifurcation characteristics of the solar wheel and the first planetary wheel under different gear moduli are investigated. The results show that: by taking the excitation frequency as the control parameter, the system includes period-1 motion, period-2 motion, quasi-periodic motion, multiperiodic motion, and chaotic motion. With the increase of gear modulus, the system mainly presents chaotic motion in the medium frequency range (0.5<ωh≤2). It shows stable period-1 motion in the high frequency range (2<ωh≤3), and the higher the modulus, the wider the high frequency range of period-1 motion. The research results can provide reference for the design and optimization of this kind of two-speed transmission system in the future.
The Anopheles leucine-rich repeat protein APL1C is a pathogen binding factor recognizing Plasmodium ookinetes and sporozoites
Authors: Zmarlak Natalia Marta , Lavazec Catherine , Brito-Fravallo Emma , Genève Corinne , Aliprandini Eduardo , Aguirre-Botero Manuela Camille , Vernick Kenneth D. , Mitri Christian
Published: February 2024

Leucine-rich repeat (LRR) proteins are commonly involved in innate immunity of animals and plants, including for pattern recognition of pathogen-derived elicitors. The Anopheles secreted LRR proteins APL1C and LRIM1 are required for malaria ookinete killing in conjunction with the complement-like TEP1 protein. However, the mechanism of parasite immune recognition by the mosquito remains unclear, although it is known that TEP1 lacks inherent binding specificity. Here, we find that APL1C and LRIM1 bind specifically to Plasmodium berghei ookinetes, even after depletion of TEP1 transcript and protein, consistent with a role for the LRR proteins in pathogen recognition. Moreover, APL1C does not bind to ookinetes of the human malaria parasite Plasmodium falciparum, and is not required for killing of this parasite, which correlates LRR binding specificity and immune protection. Most of the live P. berghei ookinetes that migrated into the extracellular space exposed to mosquito hemolymph, and almost all dead ookinetes, are bound by APL1C, thus associating LRR protein binding with parasite killing. We also find that APL1C binds to the surface of P. berghei sporozoites released from oocysts into the mosquito hemocoel and forms a potent barrier limiting salivary gland invasion and mosquito infectivity. Pathogen binding by APL1C provides the first functional explanation for the long-known requirement of APL1C for P. berghei ookinete killing in the mosquito midgut. We propose that secreted mosquito LRR proteins are required for pathogen discrimination and orientation of immune effector activity, potentially as functional counterparts of the immunoglobulin-based receptors used by vertebrates for antigen recognition.
‘So what, I’m on the roof’: Lucia Berlin’s roots in Spanish and Chilean literatures
Authors: Ellis Nina
Published: February 2024

In 2015, the North American short story writer Lucia Berlin (1926–2004) was ‘rediscovered’ when her posthumous collection, A Manual for Cleaning Women, became a New York Times bestseller. It has since been translated into more than twenty languages, and has been received with particular enthusiasm in Spain and Latin America. Many of her stories are set in Chile or Mexico, where she lived for many years. This article proposes that Berlin’s adolescence in Santiago, her bilingual education, and her studies with Spanish novelist Ramón J. Sender at the University of New Mexico had important impacts on her writing. This connection has yet to be made: Berlin is most often associated with North American ‘dirty realism’, or other anglophone movements. I argue that we are wrong to place her work exclusively in the context of her country of birth, and propose that we read her alongside the hispanophone writers she learned from. In my first section, I describe Berlin’s experience in Santiago as a young, privileged North American, and explore how this formed her identity as an outsider–insider, or insider–outsider. In my next section, I focus on Berlin’s undergraduate years in New Mexico, charting her interests in liminal and domestic spaces, which may have been encouraged by Sender. In my final section, I examine the stories with Chilean settings that she published in 1988, and ask what prompted her to return to the country of her adolescence on the page.
Reading intimacy, resistance and intertextuality in Zadie Smith’s Grand Union
Authors: García-Soriano Ana
Published: February 2024

This article focuses on Zadie Smith’s experimental short story ‘Kelso Deconstructed’, published in her first short story collection Grand Union (2019). The story reimagines the last day in the life of Kelso Cochrane, who migrated to Britain during the post-war period as part of the Windrush generation, and who was murdered in 1959. The aim of this article is twofold. Firstly, I situate ‘Kelso Deconstructed’ within Smith’s preoccupations with matters of intimacy, writing and resistance in Grand Union, and in her essay collection Intimations (2020). Secondly, I examine Smith’s rewriting of this historical event through her use of intertextual references to Toni Morrison, Francis Ponge, Leo Tolstoy and Toni Cade Bambara. Ultimately, this article argues that Smith uses multiple strategies to create proximity between readers and the historical events depicted, and to deconstruct the symbol of Kelso Cochrane to instead offer an intimate representation of a singular human being.
Legibus suis et suo iure utentes: las magistraturas epicóricas de los municipia antiquissima del Lacio
Authors: Torres-González Víctor Andrés
Published: February 2024

El Lacio fue el primer territorio en el que la República romana comenzó en el siglo IV a. C. a extender su ciudadanía más allá de los muros de la Urbs y a crear un sistema descentralizado de administración local para las ciudades que iba anexionando, ya que Roma no dejaba de ser una ciudad-estado y, por tanto, su organigrama político no era capaz de asumir el gobierno directo de esas comunidades. Así surgieron los primeros municipia, denominados antiquissima por Cicerón, a los que se les permitió seguir autogobernándose según sus propias leyes e instituciones, lo que explica las diversas magistraturas epicóricas que hubo en esta región. En el presente trabajo se pretende ofrecer una visión de conjunto sobre los tres tipos de magistrados epicóricos existentes en el Lacio: dictator, praetores y aediles. De este modo, se llevará a cabo un estudio de las fuentes literarias y, sobre todo, epigráficas para establecer una relación entre el tipo de ciudadanía concedida (civitas optimo iure o sine suffragio), la etnia (latina, volsca, hérnica) y el régimen de magistrados en vigor en cada comunidad. Asimismo, se analizará el desarrollo y las funciones de estos magistrados epicóricos en cada uno de los antiguos municipios laciales para delimitar su ámbito de competencias y sus relaciones con el resto de los cargos cívicos y religiosos de la ciudad. Finalmente, se llegará a la conclusión de que la dictadura, la pretura y la edilidad epicóricas fueron una declaración orgullosa del pasado y de la antigua posesión de la ciudadanía romana por parte de estos municipia antiquissima frente a los ordenamientos de cuatorviros y duunviros de las comunidades cívicas romanas posteriores al Bellum Sociale, aunque el sistema más eficaz y evolucionado de estas últimas acabó ejerciendo una cierta influencia en el funcionamiento de estas magistraturas epicóricas laciales.
Escena de thíasos marino en el Prepirineo aragonés: el hallazgo del opus tessellatum blanquinegro del Forau de la Tuta (Artieda, Zaragoza)
Authors: Íñiguez Berrozpe Lara María , Uribe Agudo Paula , Asensio Esteban José Ángel , Mañas Romero Irene , Angás Pajas Jorge , Ariño Gil Enrique , Navarro Caballero Milagros , Magallón Botaya María Ángeles
Published: February 2024

Presentamos los resultados del estudio técnico, iconográfico e iconológico del mosaico bícromo hallado en el yacimiento romano recientemente descubierto de El Forau de la Tuta (en Artieda, Zaragoza, enclave localizado en el Prepirineo aragonés, concretamente en la conocida como Canal de Berdún), y encuadrado cronológicamente entre finales del s. I y principios del s. II d. C. Este pavimento cuenta con una serie de particularidades que le confieren un carácter especial: su extraordinario estado de conservación, su diseño basado en una bicromía invertida con figuras diseñadas con teselas blancas sobre un fondo realizado con teselas negras y la propia iconografía, con dos amores afrontados sobre hipocampos, delfines y veneras. Estas figuras y elementos son propios de un thíasos marino, una iconografía muy popular en ambientes termales o lugares vinculados con el agua. La estancia que decoró ha sido interpretada por varias razones, tales como las propias características del mosaico además de la presencia de un bocel hidráulico y de otras soluciones aislantes de la humedad, como el uestibulum de un edificio termal de grandes dimensiones del que solo conocemos una mínima parte, ya que está siendo actualmente objeto de excavación. Para su registro y documentación se han utilizado diversas técnicas geomáticas de fotogrametría aérea, terrestre y de láser escáner 3D, metodología que ha permitido continuar con el estudio de las estructuras exhumadas a pesar de que, por motivos de conservación, se hayan tenido que volver a cubrir. El yacimiento, además, cuenta con una segunda ocupación altomedieval, conocida gracias a los materiales exhumados y también por la presencia de un silo en el mosaico que aquí analizamos.
Estela de Alionus. Una inscripción inédita de Rabanales de Aliste (Zamora)
Authors: Sánchez de la Parra-Pérez Santiago , Eguilleor-Carmona Xabier , Rodríguez-Monterrubio Óscar , González de la Fuente Francisco Javier
Published: February 2024

El municipio de Rabanales de Aliste, localizado al noroeste de la provincia de Zamora, acoge un buen número de inscripciones, principalmente estelas funerarias, que han sido objeto de estudio desde comienzos del siglo XX por diferentes investigadores. Aunque muchas de ellas han sido reutilizadas con posterioridad en paredes de casas o en la iglesia del municipio, las recientes excavaciones arqueológicas apuntan a su posible vinculación con el yacimiento de El Castrico, ocupado durante la segunda mitad del siglo I d. C. y la primera del II d. C. En este trabajo se analiza una estela funeraria inédita descubierta en 2021 empotrada en el interior de la iglesia de El Salvador, concretamente en el acceso a la base del campanario desde la nave central, que servía como sillar del dintel del vano de la puerta. Gracias al uso de técnicas novedosas como la fotogrametría digital y aplicación de análisis con SIG se ha podido leer correctamente la inscripción y descartar de la lectura algunas marcas, provocadas por las sucesivas alteraciones del bloque tras su reutilización. De esta manera, podemos minimizar el riesgo de interpretar erróneamente caracteres inexistentes en la pieza. A pesar de tratarse de una inscripción sencilla de tipo funerario, su análisis ha permitido dar a conocer la primera atestiguación del antropónimo Caraucus en el Imperio, de clara tradición celta, así como una posible relación de parentesco del tipo abuelo-padre-hijo, pudiendo completar la ascendencia familiar de otro personaje mencionado en el corpus epigráfico de Rabanales: Potitus, hijo de Alionus y nieto de Caraucus.
Estudio de las huellas de uso y aplicación de análisis químicos no destructivos sobre un macroútil procedente del yacimiento de Hort de Cortés-Volcán del Faro (Cullera, València)
Authors: Vadillo Conesa Margarita , Ramacciotti Mirco , Gallello Gianni , Jardón Giner Paula , Soler Mayor Begoña , Pastor Agustín , Aura Tortosa J. Emili
Published: February 2024

Los macroútiles han sido habitualmente marginados de los estudios, debido al peso que ha tenido la industria lítica tallada para la observación de los cambios y continuidades cronológicos y culturales. Sin embargo, estos elementos aparecen en yacimientos arqueológicos asociados a diferentes contextos geográficos y cronológicos, lo cual les confiere un valor como marcadores de la adaptación y de la evolución técnica desarrollada por los grupos humanos. En este trabajo se presentan los resultados del análisis detallado de un objeto procedente del yacimiento de Hort de Cortés-Volcán del Faro (València), asociado a niveles gravetienses. La singularidad de su morfología, de la materia prima y la presencia de huellas de uso apreciables a nivel macroscópico motivaron la aplicación de diferentes metodologías de estudio sobre la pieza para su comprensión. El análisis de las huellas de uso apunta a que esta roca carbonatada fue utilizada en actividades asociadas con el tratamiento de la piel. La diferenciación de dos grupos de huellas de uso ha determinado la distinción de dos tareas desarrolladas con el objeto. La presencia de residuos que se pueden correlacionar con el uso de la pieza se ha evaluado aplicando una aproximación multianalítica y no destructiva. Además, se han aplicado técnicas de espectroscopía atómica y molecular junto con estadística multivariante, con el objetivo de identificar la potencial fuente de materia prima. El interés de este estudio reside en la combinación de aproximaciones para el estudio de un macroútil. Todo ello ha permitido ampliar la limitada información que se tiene sobre este tipo de materiales, y abrir el debate sobre el conocimiento del nivel tecnológico alcanzado por los grupos humanos.
Paisaje ibérico en un área de transición: el valle de Caudete (Albacete)
Authors: Moratalla Jávega Jesús , Ramón Baraza Pedro , Segura Herrero Gabriel
Published: February 2024

Una modesta intervención arqueológica, vinculada a la conocida como arqueología preventiva, ha proporcionado el hallazgo de un lote de cerámicas antiguas de indudable interés y cierta trascendencia, en el cerro de Santa Ana de Caudete. Gracias a ello, conocemos con datos empíricos la naturaleza de un asentamiento hasta ahora no excavado. Y también se demuestra la necesidad de establecer protocolos de control de actuaciones urbanas sobre cualquier tipo de evidencia del Patrimonio Histórico. La excavación arqueológica permite asegurar que, con un muy alto grado de probabilidad, parte del antiguo asentamiento todavía subsiste por la umbría del cerro y puede ser ampliamente excavado, por lo que en un futuro podría convertirse en un referente patrimonial de valor social de primer orden. Si próximos planes de actuación en la zona siguen los pasos ahora dados, podremos contar con un bien arqueológico relevante para conocer el fin del mundo ibérico ante la llegada de Roma. El registro cerámico supone para la arqueología un documento de un valor incuestionable cuando pretendemos acercarnos al conocimiento de las sociedades protohistóricas. Esto queda de relieve en estas líneas para las que la exhumación de un modesto pero elocuente conjunto cerámico nos ha permitido releer y ampliar el conocimiento sobre el yacimiento de Santa Ana. De este modo, partiendo de este registro y de las variables aportadas por el estudio de su territorio circundante, hemos podido profundizar en la lectura del poblamiento ibérico situado en este sector de la cabecera del río Vinalopó y su conexión con otros nichos geográficos cercanos.
Egy felvilágosult reformer és három (ex-)jezsuita: Van Swieten, Hell, Kollár, Sajnovics – és a Demonstratio
Authors: Kontler László
Published: February 2024

This short essay revisits the question of the source of inspiration for the linguistic research that led to the composition of Sajnovics’s Demonstratio, While it has recently been suggested that the idea was improvised during the Vardø expedition of 1768-69, it is worth reconsidering Sajnovics’s superior Maximilian Hell’s testimony that the prompt was given by Gerard van Swieten, the leading figure of the Habsburg academic refoms. As Van Swieten is not known to have possessed relevant expertise, it is proposed that the real source was the polymath and Viennese court librarian Adam František (Franz) Kollár, who later also wrote the first review of the Demonstratio. The proposition is framed within the context of the increasingly uneasy but working cooperation between (ex-)Jesuit scholars and the Habsburg enlightened refomers during most of the Theresan era.
A Demonstratio magyar nyelvtani forrásai
Authors: Constantinovitsné Vladár Zsuzsa
Published: February 2024

Demonstratio (1770) is a fundamental work of comparative linguistics, it is the first scientific demonstration of the affinity of Hungarian and a Finno-Ugric language. The paper examines the Hungarian grammatical sources of Demonstratio and the Hungarian spelling system used in the work. Among the Hungarian grammatical sources, the grammars of Albert Molnár Szenczi (1610) and Pál Pereszlényi (1682) can be identified. Sajnovics referred to the Protestant morphological spelling system, however, in practice, he used the phonetic Catholic one. Sajnovics used the theory of monosyllabic roots as proof of linguistic affinity. Root theory played an important role in early language comparison as well as in later stages.
Cuerpo sin órganos de Antonin Artaud en la trascendencia de las lógicas de subjetivación. Cronotopías en «La voz de la Luna» de Federico Fellini
Authors: Romero Tenorio José Manuel , Buitrago Echeverry Carolina , Díaz Téllez Ángel Saúl
Published: February 2024

Proponemos una teoría estética basada en un enhebrado cronotópico del discurso creativo que replantea las lógicas de constitución del sujeto. Tomamos como hilo conductor la película La voz de la luna (La voce della Luna, 1990) de Federico Fellini, cuyo surrealismo, lejos de suponer una construcción al azar de un relato, revela una sofisticada narrativa desde lo circunstancial (y no desde el sujeto o el objeto). Es aquí donde confluimos con las tesis más radicales de Antonin Artaud y su proyecto político basado en el teatro de la crueldad y la reificación del fragmento-órgano. Concluimos con un alegato por una narración vital, que trascienda la obra, disipe la posición del sujeto en la misma (lo que Jacques Derrida denomina Forcener le subjectile) para que el sentido de la humanidad, en lo ínfimo y fragmentado, trasparezca.
Dos problemas sobre la invarianza para propósitos intervencionistas o de política
Authors: Ivarola Leonardo
Published: February 2024

El uso de un conocimiento invariante para alcanzar propósitos intervencionistas o de política es comúnmente aceptado por los enfoques manipulabilistas. Sin embargo, dicho uso plantea dos problemáticas filosóficas que serán examinadas en el presente trabajo. El primer problema es ontológico, y refiere a la dificultad de encontrar genuinos factores causales estables en ciencias sociales. En este sentido, se mostrará que los fenómenos sociales no responden a una lógica de factores estables como los mecanismos o las «capacidades», sino que se adecúan más a una lógica de «árboles de posibilidades” o «resultados de final abierto». El otro problema es de índole epistemológico y refiere a que, incluso si se encuentran contribuciones sociales estables, nada garantiza que dicha estabilidad prevalezca en el futuro. Diferentes tesis que avalan esta problemática serán examinadas, tales como la denominada «crítica de Lucas» o la «teoría del cisne negro».
Derechos sin Política. Hacia una crítica de los derechos en tiempos de discriminación
Authors: Martínez de Bringas Asier
Published: February 2024

Los fundamentos ontológicos y epistemológicos de los derechos humanos están siendo objeto de un profundo cuestionamiento las últimas décadas. Sin embargo, a pesar de este sintomático desgaste, estos fundamentos no han sido reemplazados por nuevas formas de entender la acción política; de espacios de negociación que pavimenten la vía para la reformulación de nuevos retos para la justicia social. En este proceso, el papel de los derechos humanos ha sido fundamental; sin embargo, los derechos reclaman ser deconstruidos y reelaborados para dar respuesta a nuevas formas de discriminación, desposesión y exclusión.
El legado del genio griego
Authors: Costa i Llobera Miquel
Published: February 2024

La tribu de los nativos del poblado de Ses Paysses reacciona con odio y violencia ante la presencia de los extraños griegos. Nuredduna descubre en la finura de espíritu del rapsoda Melesigeno que existe un nuevo mundo que enriquece su condición humana. La gran estatua de Nuredduna, de Remigia Caubet, en el Paseo Marítimo de Palma, muestra a Nuredduna mirando al mar con la mano extendida como esperando la llegada del extranjero que la abrirá a un nuevo mundo de harmonía, más universal, mucho más enriquecedor que la mirada corta que se cree dueña de lo inmediato. Este precioso mensaje del poema de Miquel Costa i Llobera tiene una evidente actualidad para Mallorca, para España, para Europa y para el mundo. Todos se ven atormentados por los nacionalismos, por las fuertes corrientes migratorias e inmigratorias, por el turismo, y, al mismo tiempo, estimulados por la llamada filosófica del hombre universal de Hegel y por la llamada cristiana a la hermandad universal. El poema de Costa es una hermosa y poética llamada a saber dejarnos llevar por la dinámica de la historia que nos mueve a superar la singularidad y abrirnos a la universalidad.
Hipocresía y barbarie. Las contradicciones dialécticas del «hombre civilizado» frente a la crueldad en la correspondencia Freud-Einstein
Authors: González Adolfo  León
Published: February 2024

En el texto «¿Por qué la guerra?» de 1933, Einstein y Freud abordan la posibilidad de educar al hombre contra la barbarie. En él se define el proceso de civilización como un predominio progresivo de la razón que tiende a la eliminación de la crueldad de la esfera social mediante la educación de los instintos primarios. Pero la intrínseca ambigüedad de la violencia (constructora y destructora) en Freud permitiría comprender la guerra civilizada como una forma histórica de crueldad estéticamente tolerable, al estar su violencia ligada a «un cierto grado de hipocresía» del Kulturmenschen necesario para mantener el orden de la civilización. En diálogo con las ideas de Adorno, Elias y Bauman, este artículo examina críticamente las contradicciones dialécticas en torno a la crueldad en el mundo moderno. En él se concluye que el ocultamiento y la negación de la violencia cruel son mecanismos necesarios para mantener la ilusión de una superioridad ética de la civilización sobre la barbarie.
Engaging Diverse Communities in a Community Science Fair
Authors: Hougham Robert , Bessler Brad , Zocher Joey , Sams Walter
Published: February 2024

Prioritizing alternative ways to encourage student interest in STEM is necessary to increase the number of students that choose a career in STEM. The traditional classroom setting that includes direct instruction may inspire some students, but when there is a significant discrepancy of students from historically marginalized populations in STEM careers, determining what can be done differently and how it can be done differently, may be the questions that result in more representation from minoritized communities.
The Great Hole in the Sky: Solar Eclipse, Radio Science and a Vision for Student Engagement
Authors: Ladwig Joachim
Published: February 2024

The BNL Stars Amateur Radio club has come back to life after an entire generation of absense.  We are active in several American Radio Relay League (ARRL) amateur events and NASA data collection activities.  We plan to be active and growing our skills until April 8, 2024.
Ocular Hazards Associated with Eclipse Viewing
Authors: Bradley Arthur , Peabody Todd
Published: February 2024

You have probably heard the warnings about direct viewing of an eclipse and the damage it can do to your eyes. What is the real threat, and how does sunlight during an eclipse pose a threat? In this article, reprinted from the 2017 Indiana University CelestFest website, hear from faculty at IU's School of Optometry about the medical information surrounding this topic.
To rule-in, or not to falsely rule-out, that is the question: evaluation of hs-cTnT EQA performance in light of the ESC-2020 guideline
Authors: van Schrojenstein Lantman Marith , Grobben Remco , van Herwaarden Antonius E. , van Berkel Miranda , Schaap Jeroen , Thelen Marc
Published: February 2024

Objectives

To accurately evaluate non-ST-elevated acute cardiac syndrome (NSTE-ACS), the quality of high-sensitive cardiac troponin (hs-cTn) assays is of vital importance. The 2020 revision of the NSTE-ACS guideline includes clinical decision-limits (CDL’s) to both rule-in and rule-out NSTE-ACS for most commercially available platforms, providing both 0/1 h and 0/2 h delta limits. Our study evaluated whether laboratories are able to meet the analytical performance specifications for imprecision (APS) for hs-cTnT.

Methods

Results from external quality assurance (EQA) in commutable samples were used to evaluate the current and historic performance of analyzers. The performance of analyzers that either passed or failed to comply with 0/1 h-APS were used on a real-world dataset of first hs-cTnT-values to simulate 10.000 samples of t=0, t=1 and t=2 h values with multiple delta’s for all relevant CDL’s. We compared the simulated values to the input values to obtain the percentage of aberrant results simulated.

Results

The majority of analyzers complies with APS for rule-in in 2022 (0/1 h: 90.4 % and 0/2 h: 100 %), compliance for the 0/1 h rule-out is still far from optimal (0/1 h: 30.7 %, 0/2 h: 75.4 %), with improving compliance over the past years (rule-in p=<0.0001, rule-out p=0.011, χ2). Whilst 0/1 h-APS-passing analyzers have a minute risk to falsely rule-out patients whom should be ruled-in (0.0001 %), failing performance increases this risk to 2.1 % upon using 0/1 h CDL’s. Here, adopting 0/2 h CDL’s is favorable (0.01 %).

Conclusions

Laboratories that fail to meet hs-cTnT 0/1 h-APS should improve their performance to the required and achievable level. Until performance is reached clinics should adopt the 0/2 h CDL’s.
When bias becomes part of imprecision: how to use analytical performance specifications to determine acceptability of lot-lot variation and other sources of possibly unacceptable bias
Authors: Thelen Marc H.M. , van Schrojenstein Lantman Marith
Published: February 2024

ISO 15189 requires laboratories to estimate the uncertainty of their quantitative measurements and to maintain them within relevant performance specifications. Furthermore, it refers to ISO TS 20914 for instructions on how to estimate the uncertainty and what to take into consideration when communicating uncertainty of measurement with requesting clinicians. These instructions include the responsibility of laboratories to verify that bias is not larger than medically significant. If estimated to be larger than acceptable, such bias first needs to be eliminated or (temporarily) corrected for. In the latter case, the uncertainty of such correction becomes part of the estimation of the total measurement uncertainty. If small enough to be acceptable, bias becomes part of the long term within laboratory random variation. Sources of possible bias are (not limited to) changes in reagent or calibrator lot variation or calibration itself. In this paper we clarify how the rationale and mathematics from an EFLM WG ISO/A position paper on allowable between reagent lot variation can be applied to calculate whether bias can be accepted to become part of long-term imprecision. The central point of this rationale is to prevent the risk that requesting clinicians confuse changes in bias with changes in the steady state of their patients.
Spectral collocation method for convection-diffusion equation
Authors: Li Jin , Cheng Yongling
Published: February 2024

Spectral collocation method, named linear barycentric rational interpolation collocation method (LBRICM), for convection-diffusion (C-D) equation with constant coefficient is considered. We change the discrete linear equations into the matrix equation. Different from the classical methods to solve the C-D equation, we solve the C-D equation with the time variable and space variable obtained at the same time. Furthermore, the convergence rate of the C-D equation by LBRICM is proved. Numerical examples are presented to test our analysis.
New local fractional Hermite-Hadamard-type and Ostrowski-type inequalities with generalized Mittag-Leffler kernel for generalized h-preinvex functions
Authors: Sun Wenbing , Wan Haiyang
Published: February 2024

In this study, based on two new local fractional integral operators involving generalized Mittag-Leffler kernel, Hermite-Hadamard inequality about these two integral operators for generalized

h

h

-preinvex functions is obtained. Subsequently, an integral identity related to these two local fractional integral operators is constructed to obtain some new Ostrowski-type local fractional integral inequalities for generalized

h

h

-preinvex functions. Finally, we propose three examples to illustrate the partial results and applications. Meanwhile, we also propose two midpoint-type inequalities involving generalized moments of continuous random variables to show the application of the results.
Facile, polyherbal drug-mediated green synthesis of CuO nanoparticles and their potent biological applications
Authors: Ansari Mohammad Azam , Al Dhneem Hassan Nassr , Ali Syed Ghazanfar , Jamous Yahya Fahad , Alomary Mohammad Nasser , Atwah Banan , Alhumaidi Maryam Saleh , Hani Umme , Haider Nazima , Asiri Sarah , Khan Firdos Alam
Published: February 2024

Copper oxide nanoparticles (CuO NPs) were synthesized using ayurvedic medicine septilin. The septilin-mediated CuO NPs were characterized using UV–Vis, fourier-transform infrared spectroscopy, X-ray diffraction (XRD), scanning electron microscope (SEM), and transmission electron microscope (TEM). The average particle size of CuO NPs was 8 nm as evident from TEM. Minimum inhibitory concentration of CuO NPs against Escherichia coli, Pseudomonas aeruginosa, methicillin-resistant Staphylococcus aureus (MRSA), and Candida albicans was found in the range of 1–2.5 mg·mL−1. CuO NPs dose-dependently decreased the biofilm formation from 0.0315 to 2 mg·mL−1, at the highest dose of 2 mg·mL−1 of CuO NPs; 92.91%, 79.84%, and 71.57% decrease in biofilm was observed for P. aeruginosa, MRSA, and C. albicans, respectively. Down-regulation of biofilm upon treatment with nanoparticles (NPs) was also observed by SEM analysis. SEM analysis also showed the change in morphological structure, and deformities in bacterial and fungal cells upon treatment of NPs. Furthermore, the anticancer efficacy of NPs was assessed using colon cancer (HCT-116). The 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay clearly showed the anticancer potential of NPs, as the concentration of CuO NPs increased, the number of viable cells decreased. The produced CuO NPs have promise for future investigations in many biological and therapeutic domains, including the treatment of microbial biofilm infections, as well as the inhibition of cancer cell growth.
Doubly weighted M-estimation for nonrandom assignment and missing outcomes
Authors: Negi Akanksha
Published: February 2024

This article proposes a class of M-estimators that double weight for the joint problems of nonrandom treatment assignment and missing outcomes. Identification of the main parameter of interest is achieved under unconfoundedness and missing at random assumptions with respect to the treatment and sample selection problems, respectively. Given the parametric framework, the asymptotic theory of the proposed estimator is outlined in two parts: first, when the parameter solves an unconditional problem, and second, when it solves a stronger conditional problem. The two parts help to summarize the misspecification scenarios permissible under the given framework and the role played by double weighting in each. As illustrative examples, the article also discusses the estimation of causal parameters like average and quantile treatment effects. With respect to the average treatment effect, this article shows that the proposed estimator is doubly robust. Finally, a detailed application to Calónico and Smith’s (The women of the national supported work demonstration. J Labor Econom. 2017;35(S1):S65–S97.) reconstructed sample from the National Supported Work training program is used to demonstrate the estimator’s performance in empirical settings.
Group structure of elliptic curves over ℤ/Nℤ
Authors: Sala Massimiliano , Taufer Daniele
Published: February 2024

We characterize the possible groups

E

(

Z
∕
N
Z

)

E\left({\mathbb{Z}}/N{\mathbb{Z}})

arising from elliptic curves over

Z
∕
N
Z

{\mathbb{Z}}/N{\mathbb{Z}}

in terms of the groups

E

(

F

p

)

E\left({{\mathbb{F}}}_{p})

, with

p

p

varying among the prime divisors of

N

N

. This classification is achieved by showing that the infinity part of any elliptic curves over

Z
∕

p

e

Z

{\mathbb{Z}}/{p}^{e}{\mathbb{Z}}

is a

Z
∕

p

e

Z

{\mathbb{Z}}/{p}^{e}{\mathbb{Z}}

-torsor, of which a generator is exhibited. As a first consequence, when

E

(

Z
∕
N
Z

)

E\left({\mathbb{Z}}/N{\mathbb{Z}})

is a

p

p

-group, we provide an explicit and sharp bound on its rank. As a second consequence, when

N
=

p

e

N={p}^{e}

is a prime power and the projected curve

E

(

F

p

)

E\left({{\mathbb{F}}}_{p})

has trace one, we provide an isomorphism attack to the elliptic curve discrete logarithm problem, which works only by means of finite ring arithmetic.
Dimensions of Global Justice in Taxing Multinationals
Authors: Dietsch Peter , Rixen Thomas
Published: February 2024

Widespread tax evasion and avoidance have recently led to both significant reforms of international tax governance and increased attention from theorists of global tax justice. Against the background of an analysis of the double challenge of effectiveness and distribution facing the taxation of multinational enterprises, this paper puts forward a taxonomy of recent contributions of the tax justice literature. This taxonomy not only opens up an original angle of interpretation on global tax justice, but also provides a vantage point from which to evaluate recent reforms by the Organisation for Economic Co-operation and Development.
Crystal structure of 2-((2,6-dichloro-4-(3,5-dimethylisoxazol-4-yl)phenyl)amino)-N-(2-(4-methylpiperazin-1-yl)ethyl)benzamide hydrate, C25H37Cl2N5O6
Authors: Xu Xiaona , Tang Wenqiang , Zhu Zhoujing , Liu Bin
Published: February 2024

C25H37Cl2N5O6, triclinic,

P

1
‾

$P\overline{1}$

(no. 2), a = 8.115(4) Å, b = 8.656(4) Å, c = 22.641(9) Å, α = 81.344(9)°, β = 80.173(9)°, γ = 65.833(8)°, V = 1423.9(10) Å3, Z = 2, R

gt
(F) = 0.0652, wR

ref
(F
2) = 0.2010, T = 173 K.
Crystal structure of 3-(benzo[d]thiazol-2-yl)-5-bromo-2-hydroxybenzaldehyde, C14H8BrNO2S
Authors: Zhao Wen-Ze
Published: February 2024

C14H8BrNO2S, orthorhombic, P212121 (no. 19), a = 4.7405(2) Å, b = 14.5781(5) Å, c = 18.3358(6) Å, V = 1267.14(8) Å3, Z = 4, R

gt
(F) = 0.0318, wR

ref
(F
2) = 0.0774, T = 273(2) K.
The crystal structure of (E)-4-amino-N′-(1-(4-fluorophenyl)propylidene)benzohydrazide, C16H16FN3O
Authors: Cui Jianqiang , Yuwen Yahuan , Zhao Meimei , Liu Bin
Published: February 2024

C16H16FN3O, orthorhombic, Pbca (no. 61), a = 12.5936(10) Å, b = 7.7308(9) Å, c = 29.568(3) Å, V = 2878.7(5) Å3, Z = 8, R
gt(F) = 0.0872, wR

ref
(F
2) = 0.1893, T = 293 K.
Crystal structure of poly[μ
3-diiodido-[μ
2-di(1H-pyrazol-1-yl)methane-κ
2
N,N′)]dicopper(I)], C7H8Cu2I2N4
Authors: Zhang Yidong , Feng Chao
Published: February 2024

C7H8Cu2I2N4, monoclinic, I2 (no. 5), a = 9.3131(14) Å, b = 4.2354(6) Å, c = 14.959(2) Å, β = 92.583(13)°, V = 2143.4(2) Å3, Z = 2, R
gt(F) = 0.0277, wR
ref(F

2
) = 0.0672, T = 293 K.