bluuebunny/crossref_metadata_2025 huggingface dataset:
Language teaching supported by argumentation and authorship
Authors: Pacífico Soraya Maria Romano
Published: January 2020

This work aims to analyze argumentation and authorship within texts written by students of elementary school following from the reading and debate of the book of children’s literature published by Ruth Rocha. This book was chosen due to the comic’s effect that circulates in it since we had the hypothesis that laughter in the literature can facilitate the assumption of authorship and the practice of argumentation in the school context. Considering the evidence marked in the language, the results show that the comic’ effect mobilized the production of meanings, and the subjects-students occupied the discursive position of author and practiced the argumentation. We observed that the texts produced by the subjects-students are interpretable (i.e., they are not copies of the literary text read), and, above all, there is argumentation on the way in which book’s characters “use” the language and how this “use” produces comic effects.
Sosyal Medya Alanına Bourdieucü Bir Yaklaşım: Facebook Üzerine Bir İnceleme
Authors: DİKKOL Selver
Published: January 2020

Alan ve habitus kavramları başta olmak üzere Bourdieu, özellikle kültürel çalışmalarda
işlevsel olan bir teori ortaya koymaktadır. Alan, yapısal bir nitelik taşıyan, belirlenmişliği
temsil eden, bireylerin amaçlarını şekillendiren, bütünsel ve ilişkisel bir kavramdır.
Habitus ise bireylerin bu alanlar içerisinde nasıl hareket ettiğini çözümleyen bir
nosyondur. Kültürel üretim/tüketim pratiklerini sanat, edebiyat ve televizyon gibi geniş
ve çok katmanlı alanların analizi yoluyla değerlendiren Bourdieu, ‘fail (agent)’olarak
kavramsallaştırdığı tüketicilerin habitusuna ve beğeni yargılarına odaklanarak bir kültür
kuramı oluşturur. Sosyal medya, gerek üretenleri gerekse kullanıcılarıyla bir bütün olarak
ele alındığında, Bourdieu’nün temel kavramlarının özgün biçimde işlediği bir mecrayı
işaret eder görünmektedir. Sosyal medya mecraları günümüzde daha çok kullanıcı
odaklı bir görünüme sahip olsa da kullanıcılar, kendilerine sunulmuş olan bu alanlarda
belli sınırlar içerisinde hareket eder. Bu sınırlar sosyal medya yaratıcılarının imkân ve
tahayyülleriyle çizilmektedir. Bu makale, alanın ve habitusun sosyal medya ortamlarında
nasıl işlediğini tartışmaktadır. Çalışmada sosyal medya mecralarından birisi olan Facebook
alan kavramıyla birlikte çözümlenmektedir. Analiz için otuz Facebook profil sayfası
incelenmiş ve elde edilen veriler habitus nosyonu ile birlikte değerlendirilmiştir. Çalışma,
sosyal medya araştırmaları için Bourdieu’nün kuramsal çözümlemelerini Facebook ve
kullanıcıları üzerinden analiz ederek sosyal medya çalışmaları için halen gelişmekte olan
kuramsal ve ampirik araştırma önerilerine bir katkı sunmayı amaçlamaktadır.
A formação da identidade de judeus e palestinos nos meios de comunicação: como se deu cobertura da Invasão da Faixa de Gaza em 2014 pelas principais revistas brasileiras
Authors: Mendes André Melo , Ferreira Juliana
Published: January 2020

Esse artigo busca entender como os palestinos e os judeus foram representados nas páginas das revistas semanais Veja, Istoé e Carta Capital em julho de 2014, quando se deu a operação conhecida como Margem Protetora. Para isso, foram trabalhadas as noções acontecimento (a partir das ideias de Louis Queré) e de enquadramento (Erwin Goffman). Ao operacionalizar tais conceitos, utilizamos como ferramenta uma análise imagética e textual baseada nos princípios de Erwin Panofsky e Roland Barthes, além do conceito de pathosformeln que Aby Warburg desenvolveu para compreender como uma imagem é capaz de sobreviver no universo simbólico de uma certa sociedade. O artigo conclui que as quatro revistas apresentaram diferentes narrativas para o mesmo acontecimento, assim como identidades distintas para os atores envolvidos nesse acontecimento. Todas as revistas utilizaram imagens que evocam a iconografia cristã.
Lições práticas do Manual de Judaísmo Carioca segundo Paulo Blank
Authors: Rozenchan Nancy
Published: January 2020

Além de se propor a dar conta de uma história de vida ou de parte dela, o romance de formação precisa se acomodar a uma série de outras classificações que, por vezes, são acopladas a uma ou mais categorias particulares. Assim é o romance Mentch, a arte de criar um homem, de Paulo Blank, que se propõe a englobar na formação do pequeno carioca Paulo todas as virtudes do ser judeu no Rio de Janeiro nos anos 50 do século passado, assim como as vivências típicas da cidade de então. Passível de ser abordado sob outras categorias, como romance da maturidade travestido de roupagem de Bildungroman ou como obra típica da cultura judaica, a apreciação do romance se presta a desentranhar aspectos do instigante universo judaico do Rio de Janeiro daquela época.
Entre-culturas: vivendo entre Brasil e Israel
Authors: Yehezkel Raquel  Teles
Published: January 2020

Entre-culturas: vivendo entre Brasil e Israel
A criação do texto literário: modos de escrever
Authors: Carvalho Ana Cecília
Published: January 2020

A criação do texto literário: modos de escrever
Novela gráfica e diferença cultural
Authors: Carvalho Rosângela Tenório , Dos Santos Gabrielle Tavares , Dos Santos Wanderson Cruz
Published: January 2020

O artigo pretende um estudo sobre diferença cultural em novelas gráficas de cunho autobiográfico. A análise descritiva com foco na forma temporal e espacial – narrativa e visual tem como corpus quatro novelas gráficas autobiograficas: Ao coração da tempestade de Will Eisner; Retalhos de Graig Thompson; A chegada de Shaun Tan; e A Força de Vida de Will Eisner. As noções de discurso, diferença, representação, subjetividade desenvolvidas nos estudos de Foucault e da noção de dessubjetivação proposta por Agamben associados aos estudos sobre a linguagem da Arte Sequencial de Eisner orientam o estudo. Os principais resultados indicam como novelas gráficas de cunho autobiográfico, originárias da arte gráfica underground em suas práticas de contra-condutas, estão implicadas com experiências de subjetivação e dessubjetivação. Chama-se atenção para o posicionamento de sujeito migrante, de raça e de gênero em sua conexão com a produção da diferença.
Poétique de la non-fiction: le discours métalittéraire dans les récits d'Emmanuel Carrère
Authors: Martínez García Patricia
Published: January 2020

Le renoncement à la fiction a donné lieu, à partir des années 2000, à un nouveau pan de l´œuvre d´ Emmanuel Carrère. Le tournant vers la non-fiction s´accompagne d´une réflexion sur l´écriture qui se déploie de façon métatextuelle et transtextuelle à l´intérieur de L´Adversaire (2000), Un roman russe (2007), Limonov (2011) ou Le Royaume (2014). Relancé d´un récit à un autre dans un mouvement constant d´autoévaluation, le discours métanarratif en vient à définir les principes d´une poétique du factuel dressée sur un « protocole de véracité » (Demanze) où il y a reconnaissance des contraintes et des limites du moi, aussi bien éthiques que cognitives. Une écriture du « scrupule » est mise en œuvre qui correspond à une « déontologie formelle » (Viart) attentive aussi bien aux conditions épistémologiques de l´établissement d´un témoignage juste qu´à ce que l´écriture peut produire comme effet sur les vies dont elle porte témoignage.
CIRI-CIRI PERSONALITI BAPA YANG DIHARAPKAN OLEH ANAK-ANAK DALAM KELUARGA
Authors: Aida Izzah Nur
Published: January 2020

Father as a head of family having a great responsibility should be an example to children and wife. However, late father has tended to be linked to bad personalities such as bad temperament, incest, physical abuse, neglecting of living, unfairness, lacking concern for the development of children and so on that, all of these problems affect these children badly.  This study was conducted to examine the characteristics of the father's personalities expected by the children in the family. The design of this study is a survey of 454 form fourth grade students who are chosen randomly (fishbowl draw). These data use descriptive statistical techniques using SPSS version 22. It showed that the majority of the children expected their father to spend time together such as travelling and eating with the family (mean = 3.75), a loving father (mean = 3.74), the father who is fair to his children (mean= 3.70). The implications of the study can help the father to know the perceptions and expectations of the children and then strives to be a good father in the family. This study is useful for responsible parties such as LPPKN, Welfare Department and so on in managing the family affairs program in Malaysia.Bapa sebagai ketua keluarga mempunyai tanggungjawab yang besar seharusnya menjadi contoh kepada anak-anak dan isteri. Namun, pelbagai krisis yang berlaku dalam konteks kekeluargaan masa kini cenderung dikaitkan dengan isu personaliti bapa yang tidak baik dalam keluarga seperti panas baran, sumbang mahram, penderaan, pengabaian nafkah, tidak adil, kurang prihatin perkembangan anak dan sebagainya yang akhirnya kesemua masalah ini memberi kesan yang buruk kepada anak-anak. Persoalan seperti apakah ciri-ciri personaliti bapa yang diharapkan menurut perspektif anak-anak wajar diberi perhatian sebagai langkah mengatasi isu ini. Justeru, kajian ini dijalankan untuk mengkaji ciri-ciri personaliti bapa yang diharapkan oleh anak-anak dalam keluarga. Desain bentuk kajian ini adalah kajian tinjauan terhadap 454 pelajar sekolah tingkatan 4 yang dipilih secara acak (fishbowl draw). Data dianalisis dengan teknik statistik deskriptif menggunakan SPSS version 22. Dapatan kajian menunjukkan majoriti anak-anak berharap agar bapa mereka meluangkan masa bersama dengan cara membawa berjalan jalan dan makan sepuasnya bersama keluarga (mean=3.75), bapa yang penyayang (min=3.74), bapa bersikap adil antara adik-beradik yang lain (min=3.70). Implikasi kajian dapat membantu bapa mengetahui persepsi dan harapan anak-anak seterusnya berusaha menjadi bapa yang baik dalam keluarga. Kajian ini dapat memberi sumbangan ilmu kepada pihak bertanggungjawab seperti LPPKN, Jabatan Kebajikan Masyarakat (JKM) dan sebagainya dalam menguruskan program hal ehwal kekeluargaan di Malaysia.
JADAL AND THE INTEGRATION OF KALĀM AND FIQH: A CRITICAL STUDY OF IMĀM AL-ḤARAMAYN AL-JUWAYNĪ’S APPLICATION OF ISLAMIC DIALECTIC
Authors: Widigdo Mohammad Syifa Amin
Published: January 2020

This article examines Imām al-Ḥaramayn al-Juwaynī’s application of jadal theory in both his legal and theological work by analyzing critically his  major writings, namely: Kitāb al-Irshād (1950), al-Kāfīya fī al-jadal (1979), al-Burhān fī uṣūl al-fiqh (1980), al-Durrah al-Muḍīyah fī mā waqaʿa fīhi al-khilāf bayn al-Shāfiʿīyah wa al-Ḥanafīyah (1986), and Tafḍīl madhhab al-Shāfiʿī ʿalā sā’ir al-madhāhib (2013). Through a hermeneutical reading of these books, I find that Imām al-Ḥaramayn’s application of jadal renders the integration of kalām and fiqh. At first, Imām al-Ḥaramayn aims to obtain knowledge with a certain level of certainty (in the forms of ʿilm or ghalabat al-ẓann) in law and theology by applying jadal in both disciplines. Then, this scholarly attempt of obtaining certainty interestingly provides an epistemological ground for the integration of kalām and fiqh. He inserts theological elements in his legal scholarship and incorporates a juridical perspective in his theological work. As a result, he “rationalizes” Shāfiʿī legal doctrines on the one hand and “traditionalizes” rational theology on the other. This epistemological foundation for the integration of kalām and fiqh is important not only because it provides a different description of Islamic intellectual history, but also redefines the concept of Sunnī in the eleventh century.
THE JAVANESE TRANSLATION OF SYAIKH ʻABD AL-QĀDIR AL-JAILĀNĪ’S HAGIOGRAPHY: AN INTERTEXTUALITY ANALYSIS OF AN-NŪR AL-BURHĀNI
Authors: Munip Abdul
Published: January 2020

The most famous manāqib (hagiography) of Syaikh Abd al-Qadir al-Jailānī in Java, is an-Nūr al-Burhānī, written by Kyai Muslih al-Marāqī, a Javanese translation of al-Barzanji’s al-Lujain ad-Dānī. However, this book has its uniqueness and can be regarded as a new book because Kyai Muslih is not only a translator but also a commentator of the book. This article aims to describe the relationship between the book and other text. By intertextuality analysis, this paper finds that an-Nūr al-Burhānī is a revision of some translation books of al-Lujain ad-Dāni that have existed before, as well as constructed by quotations from 30 books, 24 verses of al-Qur'an, 50 ḥadiṣ and some poems. The relationship of intertextuality is indicated by excerpt, expansion, modification, and conversion. The excerpt is seen in Kyai Muslih’s sounding about controversial issues related to Sufism. The expansion is found when he speaks more extensively about the issues he discusses. The modification is shown by shortening a lengthy ḥadiṣ, a citation, and a title of a book. The conversion is seen when he criticizes another opinion he regards as not valid. Finally, an-Nūr al-Burhānī serves as hypotext for the subsequent works. At least, two books in the Indonesian language, namely Terjemah Manaqib Syaikh Abdul Qadir Jailani by Moh Saifulloh al-Aziz and Penuntun Manaqib Syeikh Abdul Qadir al-Jailani by Baidlowi Syamsuri are the translations of Javanese an-Nūr al-Burhānī and not a direct translation of Arabic al-Lujain ad-Dāni. These findings underline the importance of the translator's competence in order to produce good translation works, as is modeled by Kyai Muslih.
DIALOG OF INTERFAITH AND INTERBELIEF COMMUNITIES OF PANTURA (TALI AKRAP): AN OVERVIEW FROM THE STRUCTURAL FUNCTIONAL THEORY
Authors: Sari Ama Farida , Rusnaini Rusnaini , Rejekiningsih Triana
Published: January 2020

Interfaith dialog is commonly carried out to harmonize the relationship and minimize conflicts between religious believers. This study examines how the functional structure of an interfaith community and beliefs can create harmonious interfaith relationship through an interfaith dialog held in Kudus, Central Java. This study is designed with qualitative research model by applying the phenomenological approach. The data were technically collected through interviews, observation, document studies and Focus Group Discussion (FGD). Theoretically, this study used Talcott Parsons’ structural functional theory. The results showed that the Interfaith and Interbelief Communities of Pantura (TALI AKRAP) is a system in society where the religious adherents and the flow of beliefs are the integrated elements, each of which should function one another in creating a balance in society. As a system, TALI AKRAP holds four imperative functions which are simultaneously integrated in action systems, namely adaptation, goal attention, integration and learn pattern maintenance or commonly abbreviated AGIL. The existence of adaptation between religious adherents in the community aims to understand, recognize and accept one another as an effort to realize the harmony among religious believers. The goal to be achieved is a community with concern, tolerance, lives side by side and accepts differences as a gift from the God Almighty, all of which are integrated in social dialog activities between religious believers which exist for a long time and are carried out continuously.
STRATEGI PENGEMBANGAN USAHATANI PADI SAWAH DI KAWASAN PESISIR
Authors: Dzulhajrah Andi Sitti , Saadah Saadah , Amrullah A.
Published: January 2020

This research aims to determine (1) internal factors, which become the strengths and weaknesses of rice farming in Kuri Caddi village (2) External factors, which become the opportunitie sand threats of rice farming inKuriCaddi. (3) Strategy development of rice farming in coastal area of Kuri Caddi, Sub-district of Nisombalia, District of Marusu, Regency of Maros. The result of this research identifies that there werefour aspects of internal and external factors that influenced the development of rice farming in Kurri Caddi, which were strengths, weaknesses, opportunities and threats.The strengths consists of (1) the available workers (2) cultivable land (3) farming experiences(4) farmer’s productivity. The weaknesses consists of (1) Uncertified seed (2)unbalanced fertilizer use(3) bad-timing tillage and (4) farmers are reluctant to use new farming innovation.The opportunities consists of (1) the emergence ofnew forms of employment, (2) group of farmerthat provide the distribution of farming supports and facilitiesand (3)strong community self-help. Threats consists of (1) problems of road transportation facilities (2) natural disasters and  (3)attack of pests and diseases. Strategy development that can be new innovations such as by using certifies and implementing the jajar legowo system, with achieved score 5,49. Keywords: Rice Farming in Coastal Area; Strategy Development.
Performances of MIMIC and Logistic Regression Procedures in Detecting DIF
Authors: UĞURLU Seçil , ATAR Burcu
Published: January 2020

In this
study, differential item functioning (DIF) detection performances of multiple
indicators, multiple causes (MIMIC) and logistic regression (LR) methods for
dichotomous data were investigated. Performances of these two methods were
compared by calculating the Type I error rates and power for each simulation
condition. Conditions covered in the study were: sample size (2000 and 4000
respondents), ability distribution of focal group [N(0, 1) and N(-0.5, 1)], and
the percentage of items with DIF (10% and 20%). Ability distributions of the
respondents in the reference group [N(0, 1)], ratio of focal group to reference
group (1:1), test length (30 items), and variation in difficulty parameters
between groups for the items that contain DIF (0.6) were the conditions that
were held constant. When the two methods were compared according to their Type
I error rates, it was concluded that the change in sample size was more
effective for MIMIC method. On the other hand, the change in the percentage of
items with DIF was more effective for LR. When the two methods were compared
according to their power, the most effective variable for both methods was the
sample size.
Don Francisco Fernández de Córdoba, Abad de Rute.
Authors: Durán Rodríguez Domingo
Published: January 2020

DON FRANCISCO FERNÁNDEZ DE CÓRDOBA, ABAD DE RUTEResumen: En este trabajo abordamos la figura de D. Francisco Fernández de Córdoba, el Abad de Rute, admirado historiador, genealogista, erudito humanista y experto arqueólogo. Participó de manera activa en la polémica suscitada por la aparición de las Soledades de Góngora, su amigo y ambos racioneros en la Catedral de Córdoba, siempre en defensa del nuevo estilo poético que iniciaba D. Luis. Perteneciente a la gran casa de los Fernández de Córdoba ya que era hijo ilegítimo de D. Luis Fernández de Córdoba, señor de la Zubia. Se recogen datos de su biografía aunque existen muchas lagunas documentales para completarla. Palabras clave: Abad de Rute, Fernández de Córdoba, gongorismo, erudición, Arqueología, cartas. DON FRANCISCO FERNÁNDEZ DE CÓRDOBA, ABBOT OF RUTE.Abstract: In this work we approach the figure of D. Francisco Fernández de Córdoba, the Abbot of Rute, admired historian, genealogist, scholarly humanist and expert archaeologist. He participated actively in the controversy aroused by the appearance of Soledades de Góngora, his friend and both racioneros in the Cathedral of Córdoba, always in defense of the new poetic style that D. Luis initiated. Belonging to the great family of the Fernández de Córdoba since he was the illegitimate son of D. Luis Fernández de Córdoba, the lord of the Zubia. Data is collected from his biography although there are many documentary gaps to complete it. Key words: Abbot of Rute, Fernández de Córdoba, gongorismo, erudition, Archeology, letters.
Un acercamiento a la usurpación de armerías en Francia, los Países Bajos meridionales, España e Inglaterra durante la Edad Moderna
Authors: Valle Porras José Manuel
Published: January 2020

Este artículo intenta ofrecer, desde la perspectiva de la historia social, un acercamiento de conjunto al fenómeno de la usurpación de armerías durante la Edad Moderna, comparando las situaciones existentes en Francia, los Países Bajos Meridionales, Castilla, la Navarra española e Inglaterra. Puesto que las investigaciones sobre esta cuestión son aún escasas, y dada la amplitud geográfica abarcada en este trabajo, hemos recurrido fundamentalmente a fuentes impresas de la época (leyes, tratados teóricos y obras literarias), complementadas con ediciones de fuentes de archivo y algunas aportaciones científicas. El empleo de estos datos dispersos permite reconstruir un cuadro grosso modo común a los países estudiados, caracterizado por la asimilación de las armerías a la nobleza desde finales de la Edad Media y el consiguiente uso de las mismas como instrumento de ascenso social durante toda la Edad Moderna. Frente a esta situación, los Estados intervienen para determinar el tipo de armerías que corresponde a los nobles y evitar que las usen los plebeyos para infiltrarse en la nobleza. Sin embargo, los resultados fueron en general pobres. La apropiación de escudos y timbres indicativos de nobleza, así como de armas ajenas, fue común entre los siglos XVI y XVIII, e incluso los heraldos –teóricos encargados de vigilar la corrección de los escudos de armas– participaron, corrompidos, en estas prácticas.
Institutional Support and Role in Increasing The Interdependence of Cocoa Farmers in Central Sulawesi Province
Authors: Managanta Andri Amaliel , Sumardjo Sumardjo , Sadono Dwi , Tjitropranoto Prabowo
Published: January 2020

Indonesia is the third largest cocoa producer in the world after Ivory Coast and Ghana. Central Sulawesi is a center of Indonesian cocoa commodity, yet has low improvement. This is presumably due to the lack of support of farmer institutions that were formed not based on farmers' needs or the interests of farmers. The objectives of this study were to: (1) analyze the level of institutional support for cocoa farmers in Central Sulawesi Province, and (2) analyze the role and strategy of increasing institutional support for cocoa farmers in Central Sulawesi Province. The study was conducted in four districts in Central Sulawesi Province: Poso, Sigi, Morowali Utara and Donggala Regencies. The research sample was 380 farmers. To describe the research variables used descriptive statistical analysis in the frequency table and Duncan’s Multiple Range Test (DMRT). The results showed that most farmers (70.2%–98.7%) assessed that institutional support in the contexts of marketing, capital, processing, and technical guidance were relatively low so it tended to be less conducive to increasing farmers' independence. The institutional role of those four contexts was also low categoryzed (26.6–43.0) so that it needs serious attention in an effort to increase the weak independence of farmers.
Chinese Classical Prescription(Liang-Xue-Di-Huang Decoction)for Hemohhhoidal Disease:study protocol for a randomized controlled trial
Authors: zhou qing , Shi Shuo-yang , He Zong-qi , Xu Cheng-biao , Geng Ji , Chen Tuo , Shen Zhao-feng , Zhang Dan , Jiang Feng , Chen Yu-Gen , Wu Ben-sheng
Published: January 2020

Background: Hemorrhoidal disease (HD) is one of the commonest proctologic condition in the general population. Medical therapy for HD has not been formally confirmed due to the inconsistent of results. Liang-Xue-Di-Huang Decoction, a kind of ancient Chinese classical prescription, has been used to treat HD from the 19th century in China. However, clinical research of Liang-Xue-Di-Huang Decoction in the treatment of HD is lack. We designed this study to evaluate the efficacy and safety of Liang-Xue-Di-Huang Decoction in the treatment of HD. Methods/Design: A randomized, controlled, double blind, double-mimetic agent and multicenter trial to evaluate the efficacy and safety of Liang-Xue-Di-Huang Decoction is proposed. HD patients (stage I, Ⅱ, Ⅲ) will be randomly assigned into Liang-Xue-Di-Huang Decoction with the addition of Diosmine mimetic agent, or Diosmine with the addition of Liang-Xue-Di-Huang Decoction mimetic agent. Patients will receive a 7-days treatments and a 7-days follow-up. The primary outcome measure is the French Bleeding Score in 7 and 14 days. The Secondary outcome measures are Goligher Prolapse Score and Quality-of-Life Score in 7 and 14 days. Discussion: This study will provide objective evidence to evaluate the efficacy and safety of Liang-Xue-Di-Huang Decoction in treatment of HD. Trial registration: Chinese Clinical Trial Registry. ChiCTR-1900022531.Registered 15 Apr 2019, http://www.chictr.org.cn/listbycreater.aspx.
Bioinformatics and Expression Pattern Analysis of Soybean Fatty Acid Desaturase Family Gene
Authors: Wu Nan , Jiang Long , Yu Xiaoming , Yang Xiangbo , Chen Dianyuan , Yuan Minghao
Published: January 2020

Background To clarify the homology and structural differences of seven genes in the soybean fatty acid desaturase 2 (FAD2) family and the relationship between the expression level of each gene and oleic acid content at different stages of grain development, the seven genes in this family were studied through informatics analysis and evaluation of expression patterns.Results Database analysis, phylogenetic tree analysis, transmembrane structure prediction, amino acid sequence alignment, intron exon structure analysis, and protein motif analysis were performed for seven genes in the FAD2 family. The results showed that GmFAD2-1 and GmFAD2-2b and Other genes are structurally different, and it is speculated that their functions also have weak changes. By analyzing gene expression patterns at different stages of soybean grain development, the expression levels of the family genes at different stages of grain development first increase, then decrease, and finally decrease. For stability, the correlation analysis showed that the gene expression was negatively correlated with oleic acid content, and the correlation coefficients of GmFAD2-1 and GmFAD2-2b were the largest, showing a significant negative correlation.Conclusions Bioinformatics and expression analysis of genes in the FAD2 family. Identify the structural differences of each gene, and the differences in expression levels at different stages of soybean variety and grain development, and initially identify the differences in function size and catalytic efficiency between genes, in order to create new high-oleic soybean varieties using genetic engineering Quality, providing a theoretical basis.
Relationships of Cultural Dimensions and Lactation Patterns
Authors: Shamsabadi Elham Alidadi , Savabi-Esfahani Mitra , Hashemianfar Ali
Published: January 2020

Background Proper nutrition is essential for infant growth and health. Exclusive breastfeeding is the best pattern for feeding infants in the first 6 months of life. On the other hand, lactation patterns may be influenced by cultural factors. The present study aimed to determine relationships of cultural dimensions and lactation patterns.Methods The present cross-sectional study was conducted on 452 mothers with 6-month and younger infants. Hofstede's cultural dimensions, Power Distance, Individualism vs. collectivism, Masculinity vs. Femininity, Uncertainty Avoidance, Long-Term vs. Short-Term Orientation, and Indulgence vs. Restraint were assessed using a self-administered structured questionnaire. Data was analyzed using descriptive and analytical tests (independent t-test, Eta, phi and Cramer coefficients) and SPSS 18 at a significance level of less than 0.05.Results In the masculinity-femininity dimension, the mean score of exclusive breastfeeding pattern was higher than the non-exclusive breastfeeding (3± 0.48, 2.48±0.50) and there were statistical significant differences between groups (P = 0.03). However, despite different mean scores of power distance, individualism-collectivism, uncertainty avoidance, long term- short term orientation, indulgence- restraint in different breastfeeding patterns, the differences were not statistically significant.Conclusions Masculinity-femininity as a cultural dimension was associated with lactation patterns, so that mothers with greater orientation towards masculinity had higher focus on gender roles of a woman such as breastfeeding and they had greater exclusive breastfeeding. Therefore, some cultural dimensions should be taken into consideration in training and counseling for maternal breastfeeding.
Dietary Fiber Powder Made from Purple Wheat “Jizi439” Bran: An Effective Health Food and Its Processing
Authors: Meng Yaning , Lan Suque , Zhang Yelun , Li Xingpu , Niu Zhenhua , Liu Yuping , Gu Dongye , Wang Qiaqia
Published: January 2020

Background: Different processing approaches could usually alter contents of different nutritional ingredients for wheat grains which benefits human health. The present study is aimed to assess the dietary fiber and other nutritional ingredients of purple wheat (Jizi439) bran via proper processing and to analyze its benefits to prevent diseases and enhance health so as to prove the dietary fiber powder made from purple wheat （Jizi439）to be an effective health food. Methods: Approach I Pulverizing: Purple wheat bran was put into blade pulverizer to get the pulverized bran into particles with a 60-meshdiameter. Puffing: The pulverized bran was sprayed with pure water to moisten the bran, making its moisture reach 22%. The moistened bran was put into twin-screw bulking machine under a temperature of 135 ℃ , and puffed at 400 r/min, to get puffed pellets. Milling: The puffed bran pellets were put into wall mill under 32℃ and 6 – 7 MPa and at 350 r/min to get dietary fiber powder (DFP) in particles with a 130-mesh diameter. Approach II: Except for the processing parameters, the procedure of Approach II was the same as Approach I. Results: The significant increase of nutritional elements contents in dietary fiber powder have been found when it is processed via different approaches. Different processing treatment and processing parameters bring forth different effects on the nutritional elements which are released from purple wheat bran. It is indicated that the contents of SDF produced via Approach I is greatly higher than that of the SDF produced via Approach II ( p ≤0.01), which suggests that Approach I is much effective for processing purple wheat bran for producing solvable dietary fiber Conclusions: Purple wheat bran is a high-effective health food, but only it is properly processed. Different processing has different impacts on the active substances of the purple wheat bran powder related to health function. In this study, only Approach I helps to increase the health nutritional ingredients which bring forth positive effects on the enhancement of health function, while Approach II fail to improve the function on health enhancement. Keywords: Dietary fiber powder, Purple wheat bran; Health food; Disease prevention
Prognostic effect of postoperative duration until adjuvant chemotherapy and cumulative S-1 dose in gastric cancer
Authors: Takashima Yusuke , Komatsu Shuhei , Nishibeppu Keiji , Arita Tomohiro , Kosuga Toshiyuki , Konishi Hirotaka , Morimura Ryo , Shiozaki Atsushi , Kuriu Yoshiaki , Ikoma Hisashi , Kubota Takeshi , Fujiwara Hitoshi , Okamoto Kazuma , Otsuji Eigo
Published: January 2020

BackgroundAdjuvant chemotherapy (AC) following curative gastrectomy for stage II/III gastric cancer (GC) is recommended in Japan. However, for various reasons, patients cannot always start AC at the appropriate time. This study was designed to investigate the effect of the postoperative duration until adjuvant chemotherapy (PDAC) and cumulative S-1 dose on prognosis.MethodsBetween 2008 and 2014, 76 consecutive GC patients who underwent postoperative S-1 monotherapy were enrolled in this study.ResultsPostoperative complications of Clavien–Dindo grade II or higher and postoperative peak C-reactive protein of 8 mg/dl or higher were significantly associated with delayed AC. The cut-off value of PDAC selected to most effectively stratify prognosis was 7 weeks. For relapse-free survival (RFS), patients with PDAC ≥ 7 weeks had an insignificantly poorer prognosis than those with PDAC < 7 weeks (p = 0.017, 5-year RFS: PDAC ≥ 7 weeks vs. PDAC < 7 weeks, 48.5% vs. 77.0%). A multivariate analysis showed that PDAC ≥ 7 weeks [p = 0.007; hazard ratio (HR) 3.99 (95% CI: 1.46–11.5)] and cumulative S-1 dose > 12,000 mg [p = 0.033; HR 0.38 (95% CI: 0.14–0.93)] were independent prognostic factors. In patients with a cumulative S-1 dose ≥ 12,000 mg, there were no prognostic differences between patients with and without PDAC ≥ 7 weeks.Conclusions7 weeks after surgery could be an indicator starting AC. A cumulative S-1 dose of more than 12,000 mg might be a key dose for diminishing the poor prognostic effects of delaying AC.
Finite element modeling of proximal femur with quantifiable weight-bearing area in standing position
Authors: Peng Yang , Lin Tian-Ye , Xu Jing-Li , Zeng Hui-Yu , Chen Da , Xiong Bing-Lang , Pang Feng-Xiang , Chen Zhen-Qiu , He Wei , Wei Qiu-Shi , Zhang Qing-Wen
Published: January 2020

BackgroundThe positional distribution and size of the weight-bearing area of femoral head in the standing position as well as the direct active surface of joint force can directly affect the result of finite element (FE) stress analysis, however in most studies related separate FE models of femur, the division of this area is vague, imprecise and un-individualized. The purpose of this study was to quantify the positional distribution and size of the weight-bearing area of femoral head in standing position by a set of simple methods, to realize individualized reconstruction of proximal femur FE model.MethodsFive adult volunteers were recruited for X-ray and CT examination in the same simulated bipedal standing position with a specialized patented device. We extracted these image data, calculated the 2D weight-bearing area on X-ray image, reconstructed the 3D model of proximal femur based on CT data, and registered them to realize the 2D weight-bearing area to 3D transformation as the quantified weight-bearing surface. One of the 3D models of proximal femur was randomly selected for finite element analysis (FEA), and we defined three different loading surfaces, and compared their FEA results.ResultsA total of 10 weight-bearing surfaces in 5 volunteers were constructed, they were mainly distributed on the dome and anterolateral of femoral head with crescent shape, in the range of 1,218.63mm2 - 1,871.06mm2. The results of FEA showed stress magnitude and distribution in proximal femur FE models among three different loading conditions were significant differences, the loading case with quantized weight-bearing area was more in accordance with the physical phenomenon of the hip.ConclusionThis study confirmed an effective FE modeling method of proximal femur, which can quantify weight-bearing area to define more reasonable load surface setting without increasing the actual modeling difficulty.
Incentives for Danish healthcare management based on a pilot outcome-based, patient-centric management model in psoriasis and psoriatic arthritis: the non-interventional IMPROVE study
Authors: Thomsen Simon Francis , Skov Lone , Kristensen Lars Erik , Hedegaard Morten Størling , Kjellberg Jakob , Jørgensen Tanja Schjødt , Brenøe Søren , Dodge Rikke
Published: January 2020

Background Psoriasis (PsO) and psoriatic arthritis (PsA) are chronic diseases that affect patients’ quality of life. The purpose of the present study was to develop a pilot outcome-based, patient-centric management model for PsO and PsA. Methods The non-interventional IMPROVE ( I ncentives for healthcare m anagement based on p atient- r elated o utcomes and v alu e ) study being conducted in Denmark consists of 5 phases: 1) collecting real-world evidence to estimate treatment patterns and disease burden to the healthcare sector and patients; 2) identifying disease aspects which matter most to patients by use of concept mapping; 3) conducting interviews with healthcare professionals and patient organization involved in a typical PsO or PsA patient journey in order to determine relevant measures to quantify patient-identified outcomes; 4) developing a value-based remuneration model based on outcomes from phases 1–3; and 5) testing the outcome-based model in pre-selected hospitals in Denmark. Results Both PsO and PsA are associated with multiple co-morbidities, increased healthcare costs, and loss of earnings. Seven important ‘clusters’ of disease aspects were identified for both PsO and PsA, including uncertainty about disease progression and treatments, as well as inter-personal relations with healthcare providers. Hospital-based treatment was associated with high treatment costs. Although the outcome-based model could result in strategic behavior by doctors, those involved in defining the best outcome goals consider it unlikely. Conclusion The new patient-centric outcome-based management model is expected to support optimal treatment and secure best possible outcomes for patients suffering from PsO or PsA. The practical implication of the present study are that the models developed are expected to increase focus on patient-centered healthcare, and help eliminate some of the inappropriate incentives that exist in activity-based remuneration systems.
A long term condition / disability, loneliness, and social isolation are associated with lower quality of life, but a sense of coherence buffers the adverse effects: a cross sectional study in older people
Authors: Woerden Hugo van , Angus Neil J. , Kiparoglou Vasiliki , Atherton Iain Maitland , Leung Janni
Published: January 2020

Background The impact of disability, long term conditions, rurality, living alone, and being a carer on health has some evidence base. The extent to which a strong sense of coherence, a factor hypothesised to promote wellbeing, may moderate these associations is unknown. A model of physical, environmental and social factors on quality of life was tested, with particular emphasis on whether a strong sense of coherence (SoC) buffered these determinants of quality of life.Methods A cross sectional postal survey was undertaken of a random sample of 3,000 individuals over 65 years, across a rural population. Physical, environmental, and psychological variables were assessed against quality of life using ANOVA and a generalised linear model including the interaction effects of SoC.Results Of 1,547 responses, 1,471 were analysable and provided permission for research use. ANOVA demonstrated that age, gender, long-term condition / disability (LTC-D), living alone, >20 hours unpaid care for others per week, SoC, and loneliness, were associated with lower quality of life (p<0.01). There were strong correlations (p>0.01), between age and LTC-D, living alone, and poor SoC. Living alone was correlated with emotional and social loneliness; but those with higher SoC were less likely to experience loneliness. In an adjusted generalised linear model, significant associations with a lower quality of life were observed from: LTC-D, emotional loneliness and social loneliness (B= -0.44, -0.30, and -0.39, respectively, all p<0.001). The only interaction with SoC that was statistically significant (at p<0.05) was LTC-D. A stronger sense of coherence buffered the negative effects of long-term condition / disability on quality of life.Conclusions This study is novel in examining the relationship between the presence of a LTC-D and loneliness in an older rural population. The physical, environmental and social factors examined, identified long-term conditions / disability and loneliness to be the strongest factors associated with quality of life. SoC somewhat buffered the adverse effect of LTC-D on quality of life, but did not do so for loneliness. Future research to understand what could be done to improve quality of life in a rural context is warranted.
Opioid overdose death in Wales: A linked data autopsy study
Authors: Jones Matthew Balquin , Bradshaw Ceri , Fuller Gordon , John Ann , Jones Jenna , Moore Chris , Snooks Helen , Watkins Alan
Published: January 2020

BackgroundFatal opioid overdose is a growing public health problem, the incidence of which is rising in the UK and in other western countries. We sought to describe factors associated with deaths, demographic characteristics, and service usage patterns of decedents of opioid overdose in a nation of the UK.MethodsWe carried out a retrospective cross-sectional analysis of opioid related deaths between 01/01/2012 and 11/10/2018 in Wales, UK, as identified from Office for National Statistics data. In addition to ONS records, the Welsh Demographic Service and National Health Service datasets were interrogated for records spanning the preceding three years. Records were linked on an individual basis using a deterministic algorithm. Decedents’ circumstances of death, demographic characteristics, and residency and service use patterns were described. Additionally, data pertaining to circumstances of death were briefly analysed.Results638 people died of opioid overdose in Wales between 01/01/2012 and 11/10/2018. Decedents were mostly male and around 50 years of age. Incidence per head of population was higher at the end of this period, peaking in 2015. In the 3 years prior to death the majority of decedents changed address at least once, but rarely moved far geographically. Over 80% of decedents visited the ED, the majority via emergency ambulance; over 60% were admitted to hospital; and over 30% visited specialist drug services on one or more occasion. Decedents who did not attend drug services were more likely to have died intentionally.ConclusionsHigh risk opioid users are often men of around 50 years of age living peripatetic lifestyles. It appears that those at high risk of dying from opioid overdose death use emergency medical services and are admitted to hospital comparatively often. They are less likely to visit specialist drug services however. Group differences between high risk opioid users who visit specialist drug services and those who do not appear to exist in relation to suicidality. Further research is needed in to delivering abstinence focussed or harm reduction based interventions via emergency services or inpatient hospital settings, and in understanding differences in suicidality between drug service attenders and non-attenders.
Oral Health-Related Quality of Life and Self-Esteem of Children with Post Traumatic Stress Disorder Living in War Zones: A case-control study
Authors: Hamid Sulaf Hasan
Published: January 2020

Background The aim of the recent study was to evaluate oral health-related quality of life (OHRQoL) and self-esteem (SE) in a group of Syrian children with post-traumatic stress disorder (PTSD) living in war zones and to compare results with healthy controls.Methods A total of 119 children (57 PTSD children vs. 62 healthy controls) aged between 10 and 14 years joined the present study. Child Post Traumatic Stress Disorder Reaction Index (CPTSD-RI) was utilized to confirm the diagnosis of PTSD symptoms. Child Perception Questionnaire (CPQ 11-14 ) was used to study OHRQoL. SE was measured with a subscale of the Child health questionnaire-child form87 (CHQ-CF87). T-tests for independent samples and Chi-square test utilized for in assessing the differences between groups.Results PTSD children had significantly more oral symptoms such as bleeding gums ( p =0.001), mouth and food between teeth ( p =0.000) when compared to healthy controls. They also had more troubles in sleeping ( p =0.019) and chewing hard food ( p =0.001). In addition, PTSD children had significantly ( p =0.000) more difficulty in opening their mouth wide and eating hot or cold food. They felt unsure about their selves ( p =0.009) and felt unsecure about health ( p =0.025) and appearance ( p =0.000). Children with PTSD showed troubles in attention ( p =0.001) and doing homework ( p =0.000). They also avoided both activities ( p =0.001), being around other children ( p =0.007) and even felt left out ( p =0.015) more frequently than healthy peers. SE scores were lower in PTSD children when compared to controls (60.96±18.71 vs. 81.01±11.13 respectively).Conclusions PTSD had negative impact on OHRQoL and SE of war-affected children. More studies are needed to confirm whether improving symptoms of PTSD may lead to better SE and OHRQoL.
Complete genome sequence analysis of a novel granaticin producer, Streptomyces sp. A1013Y
Authors: Zheng Shenglan , Zhu Yunping , Liu Kaifeng , Li Jinlong
Published: January 2020

Granaticin is a kind of antibiotics with the function of anticancer, antibacterial, anticoccidial. Streptomyces sp. A1013Y is a new strain isolated from soil with granaticin-producing ability. The genome information was analyzed for the further study of granaticin. The present work reported the complete genome of S. sp. A1013Y, which contains a 7,646,296 bp chromosome with an average GC content of 71.59%. A total of 7361 CDSs, including 66 tRNA genes, 18 rRNA genes and 23 clusters, were identified in the genome. With homologous recombination, an in-frame deletion mutant was constructed to confirm the granaticin cluster. The fermentation liquid of the mutant did not contain granaticin based on HPLC and LC-MS analysis, indicating that S. sp. A1013Y is a granaticin producer. Comparing the granaticin biosynthesis cluster of S. sp. A1013Y with Streptomycesviolaceoruber Tü22 and Streptomyces vietnamensis GIMV4.0001T, which were sequenced and produce granaticin, the similarity between the granaticin clusters was 78% and 83% respectively, but some genes still weren’t identified in the granaticin biosynthesis cluster. The phylogenetic analysis and ANI value between S. sp. A1013Y and other Streptomyces species, including S. vietnamensis GIMV4.0001T, were all below 85%, which showed that S. sp. A1013Y was probably a novel streptomyces strain that produced granaticin. The whole genome information of S. sp. A1013Y provides a valuable foundation for future granaticin analyses as well as biomedicine applications.
Socio-Demographic and Clinical Predictor Variables on CD4 Cell Count Change among HIV Positive adults; a Structural Equations Modelling
Authors: Seyoum Awoke , Ndlovu Principal Ndlovu , Zewotire Temesgen Zewotire
Published: January 2020

Background: The prevalence of HIV/AIDS among adult individuals has been increasing in Sub-Sahara African countries over the last decade. In Ethiopia , the prevalence of HIV among adults was 1%. Hence, 23, 000 people were newly infected with HIV and 11,000 people were died because of AIDS related illness in 2018. The purpose of this study was to identify the most significant socio-demographic, economic, individual and clinical determinants of CD4 cell count change in HIV positive adults who initiated HAART at Felege Hiwot Teaching and Specialized Hospital, North-West Ethiopia. Methods: A secondary and retrospective study design was conducted on 792 HIV positive adults. A structural equation modeling was employed to identify the socio-demographic and clinical covariates that have a statistically significant effect on the status of CD4 cell count change. Results: Literate patients, patients living with partner, patients living in urban area, patients disclosed the disease to family members, high income , ownership of cell, age and sex (male) were statistically significant variables. Conclusion: There was direct relation between socio-demographic variables with retention of HIV positive individuals in HAART program. There was also a direct and significant effect of clinical variables on adherence competence and adherence on CD4 cell change. Retention of patients in the HAART program had direct and significant effect on CD4 cell count change. This finding will be important for policy makers, health officials and for patients to easier access to healthcare service. Keywords: Socio-demographic, clinical factors, individual characteristics, Structural equation, CD4count change