bluuebunny/crossref_metadata_2025 huggingface dataset:
Leveraging investments in Ebola preparedness for COVID-19 in Sub-Saharan Africa
Authors: Ayebare Rodgers , Waitt Peter , Okello Stephen , Kayiira Mubaraka , Atim Ajok Maureen , Nakatudde Irene , Bhadelia Nahid , Lamorde Mohammed
Published: March 2020

The emergence of SARS-CoV-2 in China and transmission to more than 80 territories worldwide, including nine countries in Africa, presents a delicate situation for low-resource settings. Countries in Eastern and Central Africa have been on high alert since mid-2018 in anticipation of regional spread of the Ebola virus from the Democratic Republic of Congo. Significant investment has been made to support enhanced surveillance at point of entry and hospitals, infection control practices, clinical case management, and clinical research. With a new threat on the horizon, African countries have an opportunity to leverage the existing capacities for Ebola preparedness to brace for the imminent threat.
Estimating the global burden of antimicrobial resistance: Reflections on current methods and data needs
Authors: Midega Janet
Published: March 2020

The prioritisation of policy action, research and the evaluation of progress towards curbing the threat of Antimicrobial Resistance (AMR) is dependent on our knowledge of its burden.  The burden of AMR, like that of other causes of death and morbidity, is an important metric that not only provides the opportunity for generating and using data on periodic measures for timely and reliable updates on the prevailing disease situation and its potential to get better or worse, but also guides the development and positioning of interventions, including estimating the costs and benefits of interventions. The urgency with which AMR must be combatted as a global public health threat requires the need to determine and apply the most suitable methods, models and metrics for estimating the global burden of AMR to better inform decisions on how to best manage AMR.
Psychodiagnostics of a child
Authors: Kamenskaya Valentina , Draganova Oksana , Tomanov Leonid
Published: March 2020

The book describes the ways and methods of psychodiagnostic examination of children. The results of psychodiagnostic examination of the basis for the development of a specialized program of psychotherapy and psychocorrection, which are implemented as psychologist more successful, more reliable and more accurate than was performed psychodiagnostic assessment. Given the material on the basic methods of statistical evaluation of empirical data. Also consider the relationship of psycho-diagnostics, psycho-correction and psychological counseling.
Meets the requirements of Federal state educational standards of higher education of the last generation.
For students of higher educational institutions specializing in training 44.03.01 "Pedagogical education" profile "Preschool education" and "Primary education".
Cryptographic constructions on the basis of functions of multivalued logic
Authors: Sokolov Artem , Zhdanov Oleg
Published: March 2020

Symmetric encryption algorithms have been successfully used to protect information during transmission on an open channel. The classical approach to the synthesis of modern cryptographic algorithms and cryptographic primitives on which they are based, is the use of mathematical apparatus of Boolean functions. The authors demonstrate that the use to solve this problem of functions of multivalued logic (FML) allows to largely improve the durability of the cryptographic algorithms and to extend the used algebraic structures. On the other hand, the study of functions of multivalued logic in cryptography leads to a better understanding of the principles of cryptographic primitives and the emergence of new methods of describing cryptographic constructions.
In the monograph the results of theoretical and experimental studies of the properties of the FML, the presented algorithms for generating high-quality S-blocks for the symmetric encryption algorithms, as well as full-working samples of the cryptographic algorithms ready for practical implementation.
For students and teachers and all those interested in issues of information security.
Rosacea – How to answer the questions patients may ask?
Authors: Van Onselen Julie
Published: March 2020

Julie Van Onselen provides the answers that patients with this dermatological condition need to know
Improving motivation for self-directed training in Danish EMS personnel
Authors: Skydsgaard Kasper
Published: March 2020

Background:

Emergency Medical Services personnel's motivation to carry out self-directed training might be impaired by several factors such as work environment, pressures and training facilities. The aim of this study was to evaluate whether easy access to local training facilities would improve individual motivation for self-directed training.

Methods:

A before-and-after study of 118 Danish personnel was conducted. Participants were asked to complete two identical questionnaires, exploring their motivation and training efforts, before and after initiatives to promote training were introduced.

Results:

Response rates were 69 and 77, respectively. Motivation for self-directed training increased, on a scale from 1–10, from 5.6 to 6.7. The rating of opportunities to perform self-directed training increased from 4.1 to 5.9 and the rating of the training facilities from 3.7 to 6.3. The frequency of training sessions completed increased (every shift n=6 to 12, every second-to-third shift n=29 to 37).

Conclusion:

The increase in ratings regarding motivation and effort for carrying out self-directed training suggests that easily accessible training facilities improves individual motivation for self-directed training in emergency services personnel.
Sexual safety and sexuality in adult social care
Authors: Frankova Helena
Published: March 2020

It is sometimes difficult to gauge how effective your service is at protecting service users and staff from unwanted sexual incidents. Helena Frankova reviews the regulator's recently published report on sexual safety and its recommendations for providers
Staff care and safety in cases of sexual assault
Authors: Ridout Paul
Published: March 2020

In the wake of the sexual safety and consent report recently released by the Care Quality Commission, providers may be wondering what they can do to protect their staff if a sexual assault by a resident occurs. Paul Ridout offers guidance for this difficult situation
How to …. maintain a safe care home environment
Authors: Ashurst Adrian
Published: March 2020

In the wake of the outbreak of the coronavirus, infection control must be a priority, especially in care environments where older vulnerable people are living. Adrian Ashurst discusses how to ensure residents and staff remain safe and healthy by implementing and maintaining an excellent infection control process
Description of two new peruvian Phaegoptera (Lepidoptera: Erebidae: Arctiinae: Phaegopterina)

Authors: VINCENT BENOÎT
Published: March 2020

Two new species of the genus Phaegoptera are described from Peru: Phaegoptera touroulti sp. nov. and Phaegoptera doroshkini sp. nov. Detailed species descriptions are based upon morphological and molecular characters as well as distributional data. Key words: Arctiinae, Phaegopterina, Neotropical fauna, molecular phylogeny
MBPT Calculations of Energy Levels for 1s2 and 1snl (N=2-5) Configuration of Helium Like Lithium Ion
Authors: Manai Soumaya , Nasr Sirine Ben , Salhi Dhia Elhak , Jelassi Haikel
Published: March 2020

In this paper, we carried out accurate energy levels calculations among the lowest 49 levels arising from the 1s2 and 1snl (n=2-5) configuration of the He-like-Li ion using the standard relativistic configuration interaction (RCI) approach and the second-order many body perturbation theory (MBPT). Both methods were implemented in the relativistic atomic code FAC. The self-consistent field approximation and the Hamiltonian effects of the Breit interaction as well as the QED effects were included to the different calculation methods. To assess the accuracy of our calculations, we performed comparison to available experimental (NIST database) and previous theoretical results. Comparisons are made with the available data in the literature and good agreement has been found which confirms the reliability of our results. Comparatively to the NIST database, it was found that our calculated energy levels using three methods, mainly standard FAC, RCI and MBPT are assessed to be mainly accurate to better than 1.33%, 0.47% and 0.06%. Our data are with great interest in plasma diagnostics.
Report for Maintenance Air Cooled Chiller Power Ciat 2800X
Authors: Abed Rasheed N. , Muhammed Ramzi Qasim
Published: March 2020

In this report, the maintenance of the chiller ciat to feed the cooling capacity of the presidency of Al-Nahrain University and the student club buildings was achieved. The chiller ciat was repaired and operated by using the planning study for the maintenance and complete all faults that leads to stop the chiller from working. The results for repairing are very good and the chilled water temperature is (7 oC) to feed the air handling units, which gives the cold air inside the building to all facilities such as (offices, and hallways). According to the maintenance of the chiller ciat was utilized the best material and with cheap prices, which were brought from the local markets, such as: gat valve to open/close the chilled water that exit from the evaporator to the pumps, air vents, filters, ball bearing type (NSK-Poland) and it size was (6005Z). For repairing the package unit of the computerize center in the student club building was invented a new method that leads to cool this place with facilities such as (offices, and hallways). A better performance was achieved for the output chilled water from the chiller and the air handling units are able to give a cooled air to all facilities inside the buildings. This report is one of the first maintenance studies to repair the chiller ciat with these problems in very hot atmosphere. Where is utilized some procedure for the first time to prepare the air cooling for all offices in buildings.
The Translational Turn in Visual Culture
Authors: Di Paola Modesta
Published: March 2020

Este volumen de REGAC se propone investigar la alianza teórica entre el arte visual y la traducción. El concepto de traducción visual se relaciona con una noción hermenéutica que reflexiona sobre las complejidades del artefacto artístico contemporáneo, pero también con un intento epistemológico de reflexionar entorno a los intercambios culturales y lingüísticos que se dan entre sujetos y eventos internacionales. Los artículos reunidos en cuatro ejes temáticos, o zonas de contactos – lingüística, cultural, intercultural e intermedial - permiten validar la teorización de un giro de la traducción dentro de la teoría del arte visual en los últimos veinte años Traducción visual, traducción cultural, arte visual, interculturalidad, intermedialidad, giro de la traducción.  This issue of REGAC aims to investigate the theoretical alliance between art and visual translation. The concept of visual translation is related to both a hermeneutical notion that reflects on the complexities of the contemporary artistic artefact and an epistemological attempt at reflection on the cultural and linguistic exchanges that take place between subjects and international events. The articles collected around four thematic axes, or contact zones – linguistic, cultural, intercultural and intermedial, allow us to validate the theorization of a translational turnwithin visual cultural over the last twenty years.Visual translation, cultural translation, visual art, interculturality, intermediality,translational turn.
SEMEJANZAS VIRTUALES, TRADUCIONES VISUALES. LA IMAGEN, SU LECTURA Y SU TRADUCCIÓN EN WALTER BENJAMIN
Authors: Lesmes González Daniel
Published: March 2020

Este artículo propone una aproximación a la traducción visual a partir del pensamiento de Walter Benjamin. Nuestro hilo conductor se sitúa en el concepto de “semejanza”, y particularmente en el modo en que Benjamin pasó de considerar las relaciones entre las palabras y las cosas como “semejanzas no sensoriales” a concebir una lectura de las imágenes a partir de sus “semejanzas virtuales”. Entre la “legibilidad de las imágenes” y la teoría benjaminiana de la traducción, tratamos aquí de repensar lo virtual como visual; es decir: repensar la traducción visual en el seno mismo de lo que él llamó “imágenes dialécticas”.  This paper proposes an approach to visual translation based on the thinking of Walter Benjamin. Our guiding thread is situated in the concepts of similarity and resemblance, particularly in Benjamin's step from considering the relationships between words and things as “non-sensory similarities” to conceiving the reading of images from their “virtual similarities”. Between the “legibility of the images” and the translation theory of Benjamin, we try here to rethink the virtual as visual; that is: to rethink virtual translation that Benjamin theorized in order to expose a visual translation inside of what he called dialectical images.
TRADUCCIÓN POST-HUMANA EN LA CUARTA FASE DEL CAPITALISMO GLOBAL: TECNOLOGÍAS DIGITALES, LENGUAJES SENSORIALES Y BIG DATA. UN ACERCAMIENTO CRÍTICO DESDE EL ARTE
Authors: Matelli Federica
Published: March 2020

A partir del concepto de traducción y de comunidad de humanos y no – humanos de Bruno Latour, y retomando algunos conceptos estéticos centrales en la OOO (Ontología Orientada a los Objetos), este articulo expone un tipo de traducción post-humana estrechamente relacionada con la situación global del capitalismo computacional. En este orden extremo del capitalismo global, que está gobernado por algoritmos y condicionado por techno - políticas, la difusión transnacional de las tecnologías digitales instaura un lenguaje sensorial único que traduce, uniformándolas, culturas distintas y al mismo tiempo garantiza el control sobre el presente y el futuro por medio del Big Data, así como nos advierte Armen Avanessian. Su máximo agente es el design de objetos tecnológicos y servicios. A partir de esta constatación se aporta el ejemplo de un proyecto artístico que, trabajando con la traducción de datos por medio de un diseño alternativo, desvela este estado de la cultura digital actual, traduciendo y explicitando las funciones ocultas de algunos objetos digitales de uso cotidiano –como el teléfono móvil– en una instalación con objetos tecnológicos y mapas de datos. Based on the Bruno Latour’s concept of translation and community of humans and non - humans, and retaking some central aesthetic concepts in the OOO (Object Oriented Ontology), this article exposes a type of post-human translation closely related to the global situation of computational capitalism. In this extreme order of global capitalism, which is governed by algorithms and conditioned by techno - policies, the transnational diffusion of digital technologies establishes a unique sensory language that translates, unifying them, different cultures and at the same time guarantees control over the present and the future through Big Data, as Armen Avanessian warns us. Its maximum agent is the design of technological objects and services. From this finding, the example of an artistic project is provided that, working with the translation of data through an alternative design, reveals this state of the current digital culture, translating and explaining the hidden functions of some digital objects for everyday use –Like the mobile phone– in an installation with technological objects and data maps.
Multi-scale X-ray phase-contrast tomography of murine heart tissue
Authors: Reichardt Marius , Frohn Jasper , Khan Amara , Alves Frauke , Salditt Tim
Published: March 2020

The spatial organization of cardiac muscle tissue exhibits a complex structure on multiple length scales, from the sarcomeric unit to the whole organ. Here we demonstrate a multi-scale three-dimensional imaging (3d) approach with three levels of magnification, based on synchrotron X-ray phase contrast tomography. Whole mouse hearts are scanned in an undulator beam, which is first focused and then broadened by divergence. Regions-of-interest of the hearts are scanned in parallel beam as well as a biopsy by magnified cone beam geometry using a X-ray waveguide optic. Data is analyzed in terms of orientation, anisotropy and the sarcomeric periodicity via a local Fourier transformation.
Modulation-format-independent in-band OSNR monitoring technique using Gaussian process regression for a Raman amplified multi-span system with a cascaded filtering effect
Authors: Hu Chunjie , Zheng Hao , Li Wei , Feng Qiguang , Mei Muyang , Wang You , Yan Ran
Published: March 2020

We propose and experimentally demonstrate an accurate modulation-format-indepen-dent and cascaded filtering effect (CFE) insensitive in-band optical signal-to-noise ratio (OSNR) monitoring technique enabled by Gaussian process regression (GPR) utilizing a widely tunable optical bandpass filter (OBPF) and optical power measurements. By adjusting the center frequency of a widely tunable OBPF and measuring the corresponding output optical power as the input features of GPR, the proposed OSNR monitoring technique is experimentally proven to be transparent to modulation formats and robust to CFE, chromatic dispersion (CD), polarization mode dispersion (PMD), and nonlinear effect (NLE). Experimental results for 9-channel 32Gbaud PDM-16QAM signals with 50GHz channel spacing demonstrate OSNR monitoring with the root mean squared error (RMSE) of 0.429 dB and the mean absolute error (MAE) of 0.294 dB, in the OSNR range of -1∼30 dB. Even better, our proposed technique has the potential to be employed for link monitoring at the intermediation nodes and can eliminate the necessity to know the transmission information.
Of shame and humiliation in Ladri di biciclette: 'Ciccio formaggio' and 'Tammurriata nera'
Authors: Francese Joseph
Published: March 2020

In what follows I analyse how two Neapolitan songs enhance viewer perspective of the personalities of the protagonists of the classic film of Italian neorealism, Ladri di biciclette (Bicycle Thieves) by , Antonio Ricci and his son Bruno. The first, 'Ciccio formaggio', casts into relief Antonio's masculine self-image, particularly his reaction to the impact of unemployment on his traditional role of pater familias and to the possibility of public humiliation, should he fail to retrieve his bicycle. While 'Ciccio' sheds light on the tension in the marital relationship, 'Tammurriata' allows the viewer to consider Bruno's marginalization within a self-perpetuating cycle of poverty, thus shifting focus, at least partially, from the father to the long-term effects on the son (for which Antonio feels shame born of inadequacy).
Kids of the Black Hole: The First Two Decades of Punk in Orange County, Chapman University in Orange Frank Mt. Pleasant Library of Special Collections & Archives, Orange, California, 12 September 2018–18 December 2019
Authors: Johnson Denise M.
Published: March 2020

Review of: Kids of the Black Hole: The First Two Decades of Punk in Orange County, Chapman University in Orange Frank Mt. Pleasant Library of Special Collections & Archives, Orange, California, 12 September 2018–18 December 2019
Posible impacto socioeconómico por sismo de moderada magnitud. Aplicación a la ciudad de San Cristóbal, Cuba occidental
Authors: Ordaz Hernández Alexis
Published: March 2020

El artículo aborda las pérdidas socioeconómicas esperadas por un sismo de moderada magnitud para la ciudad de San Cristóbal en el occidente de Cuba. Esta localidad experimentó un sismo con magnitud estimada de 6.0 grados Richter e intensidad VIII grados MSK el 23 de enero de 1880, el cual destruyó gran parte de la infraestructura de la época. En el trabajo se definen de manera precisa los niveles de peligrosidad sísmica en función de las características geológicas locales para los periodos de retornos (T) de 100 y 475 años. Posteriormente, se estiman los niveles de daños a la infraestructura residencial empleando información catastral y las matrices de probabilidad de daños diseñadas por el Centro Nacional de Investigaciones Sismológicas de Cuba (Cenais).Para las condiciones actuales de vulnerabilidad estructural y los niveles de peligrosidad sísmica estimados, se pronostica que 5 680 viviendas sufrirán algún tipo de daño, esto en caso de que ocurriera un sismo similar al del 23 de enero de 1880. De igual forma, en función de la distribución de los habitantes en el espacio urbano, se pronostica que 67 personas queden sin hogar, 59 resulten heridas y una fallezca. La metodología empleada sirve de modelo para otros sitios en el entorno geográfico del Caribe que carezcan de evaluaciones básicas de estimaciones de daños frente a terremotos.
Designing an Experience: Maps and Signs at the Archaeological Site of Ancient Troy
Authors: Nestel Chelsea M
Published: March 2020

Maps and signage are essential for visitors to understand and appreciate the cultural, historical, and natural importance of a heritage site. Unfortunately, the on-site maps and signage at the archaeological site of ancient Troy near Çanakkale, Turkey, create a poor visitor experience. A UNESCO report found that the site suffered from “poor and confusing wayfinding” and “visual clutter and chaos” (Riorden 2009, 9–10). To understand how the maps and signage failed to help visitors, I completed a content analysis of the maps and signage found at Troy in summer 2014, based on recommendations from the semiotics of cartography and the field of experiential graphic design. The analysis uses a case study of the archaeological site of Ancient Troy to derive insights into user experience design at preserved sites of cultural or historical significance.
Reading in Phenomenology: Heidegger’s Approach to Religious Experience in St. Paul and St. Augustine
Authors: O’Rourke Jonathan
Published: March 2020

The importance of religious figures in Heidegger’s early development has long been understood. Beginning especially in the WS-1920, with the Phenomenology of Religious Life lectures, figures such as Paul and Augustine played essential roles in his early attempt to move beyond the legacy of Cartesian thought. Despite appearing to secularize these accounts, Heidegger nonetheless implies that it is because of their religiosity, and not in spite of it, that they are of phenomenological interest. For this reason, the exact status of religious descriptions in his phenomenology has been a source of contention. My argument in this paper, is that this status is best understood by turning to Heidegger’s early approach to phenomenological reading. This approach, I argue, is grounded in a performative model of language, exemplified in Destruction [Destruktion], and defines the limits within which he can engage with the religious character of historical texts.
Improving Analyses of Sanctions Busting
Authors: Golub Jonathan
Published: March 2020

When economic sanctions are directed against a target state by a sender state, the sender obviously wants third countries to participate with the sanctions and can apply pressure on them to prevent sanctions busting behaviour. But why does sanctions busting vary, so that the target’s trade with some third-countries increases but with others decreases? In this paper I offer two improvements to the analysis of sanctions busting: a theoretical framework that recognises how the effects of covariates on sanctions busting can only be identified if we treat them as more conditional than previous studies have done, and a gravity model that captures these conditional effects while also addressing several common specification errors. Applying these improvements to data for 1950–2006 significantly alters some of the central findings contained in previous research about sanctions busting.
A possible alternative therapy for type 2 diabetes using Myristica fragrans Houtt in combination with glimepiride: in vivo evaluation and in silico support
Authors: Nasreen Waheeda , Sarker Suchitra , Sufian Md. Abu , Md. Opo F.A. Dain , Shahriar Mohammad , Akhter Rumana , Halim Mohammad A.
Published: March 2020

The current study aimed to evaluate the in vivo hypoglycemic potential of Myristica fragrans seed extract co-administered with glimepiride in Swiss albino mice. Computational tools were used to further verify the in vivo findings and to help compare this combination to the glimepiride-pioglitazone combination in terms of the binding affinity of the ligands to their respective target protein receptors and the relative stability of the drug-protein complexes. The effect of the combined therapy was observed both in alloxan- and glucose-induced hyperglycemic Swiss albino mice. The mean fasting blood glucose level of the test groups was measured and statistically evaluated using Student’s t test. The combined therapy significantly reduced the blood glucose level in a time-dependent manner compared to glimepiride alone. The binding affinity of glimepiride was found to be −7.6 kcal/mol with sulfonylurea receptor 1 in molecular docking. Conversely, macelignan-peroxisome proliferator-activated receptor (PPAR) α and macelignan-PPAR γ complexes were stabilized with −9.2 and −8.3 kcal/mol, respectively. Molecular dynamic simulation revealed that macelignan-PPAR α and γ complexes were more stable than pioglitazone complexes. The combination shows promise in animal and computer models and requires further trials to provide evidence of its activity in humans.
Comunicação entre equipes e a transferência do cuidado de pacientes críticos
Authors: Petry Letícia , Diniz Marisa Basegio Carretta
Published: March 2020

Objetivo: compreender o processo de comunicação entre os profissionais de saúde durante a transferência do cuidado intra-hospitalar do paciente crítico. Métodos: estudo qualitativo, com coleta de dados por meio de entrevista com técnicos de enfermagem, enfermeiros e médicos atuantes na Unidade de Emergências Médicas e Unidade de Terapia Intensiva Adulto, perfazendo 18 profissionais. Os dados foram apreciados segundo o Discurso do Sujeito Coletivo. Resultados: evidenciou-se fragilidades no conhecimento dos profissionais quanto aos seus papeis e uma comunicação verbal estabelecida de modo superficial, como repercussão da impropriedade na utilização do instrumento de transferência existente, dificultando a obtenção de uma linha de cuidado contínua. Conclusão: a transferência do cuidado é executada entre os cenários, entretanto, o processo de comunicação se estabelece de maneira frágil e apresenta lacunas decorrentes da inexistência de um protocolo e do pouco reconhecimento acerca de sua importância por parte dos profissionais.
Condições de saúde e características do trabalho de enfermeiros de um hospital universitário
Authors: Pimenta Cláudia Jeane Lopes , Vicente Mateus Carneiro , Ferreira Gerlania Rodrigues Salviano , Frazão Maria Cristina Lins de Oliveira , Costa Tatiana Ferreira da , Costa Kátia Neyla de Freitas Macedo
Published: March 2020

Objetivo: analisar o perfil sociodemográfico, as condições de saúde e as características do trabalho de enfermeiros. Métodos: estudo transversal, realizado com 152 enfermeiros de um hospital universitário. Utilizou-se de instrumento estruturado, o qual foi analisado por estatística descritiva. Resultados: os enfermeiros consideraram a saúde como boa (50,7%), realizavam atividade física (53,3%), não fumavam (92,8%), não consumiam álcool (56,6%), apresentavam algum problema de saúde (63,2%) e utilizam medicamentos diariamente (54,6%). Observou-se maior quantitativo de profissionais do ambulatório (17,8%) e clínica médica (15,8%), que atuavam no hospital estudado por até cinco anos (61,2%), celetistas (74,3%), sem outro vínculo empregatício (54,6%), do turno diurno (56,6%), com escala de seis horas (36,2%), que referiram ausência do trabalho por até cinco dias (38,2%), devido a problemas de saúde (41,4%). Conclusão: percebeu-se presença de processos de adoecimento entre os profissionais, os quais podem interferir na qualidade e segurança do cuidado prestado.
Monitorização de complicações pós-operatórias no ambiente domiciliar
Authors: Sousa Alvaro Francisco Lopes de , Hermann Paula Regina de Souza , Fronteira Inês , De Andrade Denise
Published: March 2020

Objetivo: propor uma diretriz de monitorização de complicações pós-operatórias de pacientes no ambiente domiciliar. Métodos: pesquisa desenvolvida por meio da técnica Delphi com 45 profissionais de saúde brasileiros. Utilizaram-se o Google Forms para coleta de dados e a escala Likert para fins de consenso. Os dados foram analisados utilizando técnicas qualitativas (análise de conteúdo) e quantitativas (análise de frequências e percentuais). Resultados: foram elencadas 16 complicações elegíveis para serem utilizadas no monitoramento de pacientes cirúrgicos no pós-alta, sinais e sintomas a serem observados, frequência e tempo de monitoramento. De acordo com os juízes, é necessário o monitoramento, ao menos uma vez por dia (68,8%), do egresso cirúrgico. O tempo máximo de monitoramento apresentou variação de 48 horas até 30 dias, no caso de risco de infecção. Conclusão: a diretriz se mostra válida para ser usada na detecção de complicações em egressos cirúrgicos no domicílio e antever a necessidade de reinternação.
Persistent cortisol response to desmopressin predicts recurrence of Cushing’s disease in patients with post-operative corticotropic insufficiency
Authors: Cambos S , Mohammedi K , Castinetti F , Saie C , Young J , Chanson P , Tabarin A
Published: March 2020

Objective

Cushing’s disease (CD) may recur despite corticotropic insufficiency (COI) following pituitary surgery. The predictive value of the desmopressin test (DT) for recurrence in this setting remains controversial. We have evaluated whether the disappearance of the response to DT predicts a low probability recurrence in a large cohort of patients with post-operative COI.

Design

Multicentre retrospective study.

Methods

Ninety-five patients with CD (women 82%, age 41 ± 14 years), responding preoperatively to DT and with early post-operative COI (08 00 am cortisol: <138 nmol/L), underwent a DT within 3 months post-surgery. Association between DT findings and the prediction of recurrence was tested using regression and ROC analyses.

Results

Recurrence occurred in 17/95 patients within 29 to 91 months. The cortisol peak (327, 95% CI (237–417) vs 121 (79–164) nmol/L, P = 0.0001) and absolute increment during DT (208 (136–280) vs 56 (22–90) nmol/L, P = 0.005) were greater in the recurrence vs remission group. Cortisol peak (AUC: 0.786 (0.670–0.902)) and increment (0.793 (0.672–0.914)) yielded a higher prognostic performance for recurrence than did the early post-operative 08 00 am cortisol (0.655 (0.505–0.804)). In the context of COI, cortisol peak >100 nmol/L and increment >30 nmol/L had a high negative predictive value (94, 95% CI (88–100) and 94, (88–100), respectively). Patients with a cortisol peak ≤100 nmol/L (vs >100) or an increment ≤30 nmol/L (vs >30) were less likely to have CD recurrence (odds ratios: 0.12, 95% CI (0.03–0.41) and 0.11 (0.02–0.36), respectively).

Conclusion

The disappearance of the response to the post-operative DT was independently associated with a lower odds of CD recurrence and offers an incremental prognostic value, which may help to stratify patients with COI and refine their follow-up according to the risk of recurrence.
Konsep Tafakkur Dalam Alquran Dalam Menyikapi Coronavirus Covid-19
Authors: Indriya Indriya
Published: March 2020

Abstract:Tafakkur in Arabic is interpreted as an act of thinking to bridge the perceptions and conceptions of this world life to the afterlife, and from creatures to their Creator, namely Allah. Tafakkur goes beyond this life to a wider region, the hereafter, and transcends the superficiality of materialism to a deeper horizon, that is "spirit" which can motivate all external and internal activities of Muslims. According to Ibn Khaldun in the book Mukadimmah has a fairly broad understanding. Education is not only a teaching and learning process that is limited by four walls, but education is a process in which humans consciously capture, absorb, and experience natural events throughout the ages. This study aims to treat the epidemic of the Covid 19 virus corona with an Islamic Education perspective approach. This research is a qualitative research with a literature review approach. The results found that the tafakkur corona Covid 19 virus in the perspective of the Islamic religion produced findings through, namely; first, quarantine, namely isolating the area affected by the plague is an appropriate action; Second, be patient; Third, be kind and work hard; Fourth, pray a lot.Keywords: Tafakkur, Islamic Religious Education, Corona virus Covid 19 AbstrakTafakkur dalam bahasa Arab diartikan sebagai tindakan berpikir untuk menjembatani persepsi dan konsepsi dari kehidupan dunia ini ke kehidupan akhirat, dan dari makhluk ke Penciptanya, yaitu Allah Swt. Tafakkur melampaui hidup ini ke wilayah lebih luas, akhirat, dan melampaui kedangkalan materialisme menuju horizon lebih dalam, yaitu “ruh” yang dapat memotivasi seluruh aktivitas eksternal dan internal kaum muslim. Menurut Ibn Khaldun di dalam buku Mukadimmah mempunyai pengertian yang cukup luas. Pendidikan bukan hanya merupakan proses belajar mengajar yang dibatasi oleh empat dinding, tetapi pendidikan adalah suatu proses dimana manusia secara sadar menangkap, menyerap, dan menghayati peristiwa-peristiwa alam sepanjang zaman. Penelitian ini bertujuan untuk men-tafakkuri wabah corona virus Covid 19 dengan pendekatan perspektif Pendidikan Islam. Penelitian ini merupakan penelitian kualitatif dengan pendekatan literature review. Hasil penelitian menemukan bahwa tafakkur corona virus Covid 19 dalam perspektif Agama Islam menghasilkan temuan melalui, yaitu; pertama, karantina yaitu mengisolasi daerah yang terkena wabah adalah sebuah tindakan yang tepat; Kedua, bersabar; Ketiga, berbaik sangka dan berikhtiarlah; Keempat, banyak berdoalah.Kata Kunci: Tafakkur, Pendidikan Agama Islam, Coronavirus Covid 19
Peculiarities of the regional policy of Ukraine in the context of unified national identity formation
Authors: Lisovsky Volodymyr
Published: March 2020

The author considers the degree of scientific development of the regional policy problem as an important component of the development of Ukraine. Conceptual principles of spatial regionalism, their essence and methods of research are substantiated. The attention is paid to the study of spatial patterns of regions development and to the features of the "center-regions" relations system development. Significant attention is paid to the study of trends in regionalization as a priority improvement of regional economic policy and mechanisms for its implementation. The greatest interest here is the institutionalization of the relations of state power with subnational territories; the division of powers between the regional authorities and the representatives of the central administration. The main goal of local authorities should be to provide a variety of quality services to communities with optimal costs in open activities and accountability to the community and the state. The modern theoretical and methodological foundations of regional social systems research are highlighted. Attention is paid to the problems of securing national interests, in particular the achievement of the unity of Ukrainian society, the observance of the integrity of the state, which is realized through the formation of a common identity of the citizens of Ukraine and is a prerequisite for the viability of the state, the effectiveness of its policy and the full implementation of national interests. It is established that the key to understanding the peculiarities of creating a single identity, which will unite the majority of Ukrainian citizens, is the prerequisite for forming a political nation in Ukraine as a community, belonging to which is based on citizenship, approval of common values of the state, unity of representatives interests of different ethnic, linguistic, regional and religious-confessional groups of Ukraine. The achievement of internal consolidation of Ukrainian society, on the one hand, is a favorable factor for qualitative and internal political transformations; and, on the other hand, to strengthen the foreign policy positions of independent Ukraine.
The idea of creating a national armed forces in the socio-political discourse of the Ukrainian SSR in the 80s–90s of the 20th century
Authors: Tkachuk Andriy
Published: March 2020

The article deals with the process of initiation and implementation of the idea of creating the Armed Forces of Ukraine in the social and political discourse of the USSR in the late 1980s – early 1990s. The positions of key pro-Ukrainian public associations and movements, their programs, and statements concerning the "Ukrainianization" of the military forces that were located in the USSR are explored. An estimation of the position of these forces on public policy in the military sphere is given. It has been found out that the majority of the public associations and movements created under the conditions of "restructuring" insisted on the need for de-ideologization and demilitarization of social and political life. In most cases, members of such organizations required on the need to form military units based on the existing USSR armed forces exclusively from residents of the republic, who would report directly to the leadership of the USSR. Besides, the demand for military service by USSR citizens only within the republic remained one of the principal in the speech of Ukrainian associations and movements. The main proposals for possible reform of the military sphere on the territory of the republic are outlined. The author points out that among the Ukrainian intelligentsia, there were different visions regarding the ways of creating such forces. One part insisted on the creation of armed forces subordinated to the government based on and in the composition of the armed forces of the USSR. The other required a complete reboot of the military sphere, the introduction of a new approach to the army formation, and, ultimately, the creation of an army of an independent Ukraine. Much attention is given to the youth’s opinion about the ideologization and militarization of the Soviet high school. Representatives of the student youth were much more active than other social groups, expressing their dissatisfaction with the current situation, which resulted in spontaneous protests against the authorities. It was concluded that, at the turn of the 1980s and 1990s, the issue of military development was one of the key issues in the activities of Ukrainian unions, movements, and the first political parties. The members of these organizations were aware of the need to create an armed force in Ukraine that could counteract potential threats to state sovereignty. Such policies have resulted in numerous political actions, strikes, and demonstrations, which have been used as a mechanism to put pressure on the authorities to achieve individual political goals. In the end, under public pressure, as well as in the context of disintegration processes in the USSR, these requirements were fulfilled, which created the necessary basis for the creation of the Armed Forces of Ukraine.
Value senses of public understanding in Ukraine
Authors: Komarova Tetyana
Published: March 2020

Value senses are considered in the context of dynamics of Ukraine’s political system in information epoch. Stability of a political system depends on its ability to respond effectively to challenges, to adapt to internal and external changes. The importance of objective socio-economic indicators, choice of priorities of state policy and availability of common, recognized by majority of citizens, socio-cultural and spiritual values and meanings for normal functioning of the country are emphasized. Attention is focused on one of the key factors of stabilization – maintaining and enhancing of national understanding concerning major national development tasks, goals and axiological meanings. A necessary condition for stable development is formation of an information space that corresponds to main values of national socio-cultural field. This space, in turn, has its positive and negative sides, and therefore carries some risks. The necessity for creation an effective model of value senses of public understanding of a complex approach, which provides ensuring of freedom as a security by the state. It is emphasized that it is important to harmonize challenges related to both tradition and innovations in order to achieve a stable state of society.The specific contradictions between these components under the present Ukrainian conditions are revealed. The content of axiological guidelines, which are priority for forming stability of both society and political regime, was analyzed. Two models of political stability (total and dynamic) of society and their characteristics are considered. The current state of destabilization of Ukrainian society is indicated: significance of the contingency factor has increased critically and the important regulatory and controlling functions have been lost by the power. The need for authorities and society to work together to restore the original model of understanding that existed at the beginning of Ukraine’s independence was noted.Significant part of responsibility for this state of affairs, especially for widen the division in Ukrainian society, lays in domestic political elite, which, instead of mobilizing values in socio-political space and uniting the efforts of citizens around constructive development goals, seeks to rely on external support.
Essential Fundamentals of Armed Violence through the Prism of the Phenomenon of Social Violence
Authors: Bader Anton
Published: March 2020

The article comprehensively examines the social sources of armed violence, as one of the important phenomena in the development of humanity. Based on the analysis of works by leading Ukrainian and foreign scientists, the author considers the essence of the phenomenon of armed violence in the context of the development of social violence. In particular, a significant number of scientific papers have been analyzed, in which certain aspects of the topic chosen for research are disclosed, the main approaches and concepts that have developed in the process of studying this issue are identified and characterized.The complex characteristic of the basic concepts that studied in the article is presented. The term "social violence" the author understands as the application by one class or another of a social group of various forms of coercion, up to armed influence, against other classes and social groups in order to obtain or maintain economic and political dominance, to gain these or those rights or privileges. Accordingly, armed violence is interpreted as a way to achieve the goals using weapons. The author agrees with the opinion of a significant number of scientists regarding the definition of armed violence as a radical form of the use of social violence.As a result of the research, the author has come to the conclusion that violence has been characteristic of the human environment since its occurrence. As most scholars have noted, since the emergence of social relations, violence, including armed violence, has been one of the most important ways to achieve the goals of controlling and asserting dominance in other members of social communities. Armed violence is the most radical form of achievement of the aforementioned goal. As a form of social interaction, as noted by psychologists, armed violence is the result of the transformation of animal instincts that, in the course of social evolution, have evolved into one of the specific forms of struggle for domination within complex human communities. This is the main scientific value of the articles analyzed in the article.At the same time, as the analysis of the researched works has shown, the further classification of the types of armed violence according to the spheres of its application in social life and its varieties, according to the tasks, which are realized in the process of its use, needs further consideration. The article assumes that the most important criterion for the classification of violence is the use of weapons in this process. It is noted that no one can doubt that armed violence is violence. It is suggested to consider the main goal of most unarmed forms of social violence − the prevention of armed forms of confrontation. These aspects will be addressed in future scientific publications
Immobilization of bromelain on cobalt-iron magnetic nanoparticles (CoFe2O4) for casein hydrolysis
Authors: García Colmenares José Mauricio , Reyes Cuellar Julia Constanza
Published: March 2020

By means of recycling an enzyme, bromelain was used in casein hydrolysis facilitated by a nanobiocatalyst consisting of bromelain, CoFe2O4 magnetic nanoparticles, chitosan, and glutaraldehyde. Bromelain was immobilized on the chitosan cobalt-magnetite nanoparticle surface via covalent bonds to form the nanobiocatalyst. Immobilized bromelain showed 77% immobilization binding, retaining 85 ± 2% of the initial catalytic activity. Nanoparticles and immobilized bromelain were characterized using UV-Vis and IR spectroscopies, X-ray, square wave voltammetry (SWV), cyclic voltammetry (CV), vibrating-sample magnetization (VSM), and transmission electron microscope (TEM). The Michaelis-Menten constant (KM) and VMAX of the free and immobilized enzyme were calculated: KM = 2.1 ± 0.18 mM and 1.8 mM, respectively and VMAX = 6.08 x 10-2 ± 2.1 x 10-2 U/min and 6.46 ± 0.91 U/min, respectively. The thermal stability of the free enzyme was higher than the immobilized enzyme: 95-98% and 83-87%, respectively. An optimum pH of 6 and a temperature of 20 °C were determined in both cases. Immobilized bromelain maintained 50% of the initial catalytic activity after the fifth use. The immobilized bromelain proved to be effective and reusable for casein hydrolysis. As novel contribution the characterization by VOC and CV was carried out.
Fungicidal activity of volatile organic compounds from Paenibacillus bacteria against Colletotrichum gloeosporioides
Authors: Coconubo Guio Laura Carolina , Sinuco León Diana Cristina , Castellanos Hernández Leonardo
Published: March 2020

Some bacteria release volatile organic compounds (VOCs) that can influence the growth of other microorganisms including some pathogens. Identifying bacteria with antifungal activity makes it possible to use such bacteria in the development of biocontrol agents. Thus, the present study focuses on screening VOCs released by eight isolates from Paenibacillus genus, collected at Old Providence and Santa Catalina coral reef (Colombian Caribbean Sea), with antifungal activity against phytopathogenic fungi Colletotrichum gloeosporioides 26B. The VOCs from Paenibacillus sp (PNM-50) showed inhibition rates higher than 50% in the mycelial fungi growth accompanied by macroscopic morphological changes and a reduction in conidiation. In order to identify the VOCs responsible for this antifungal bioactivity, Headspace-Solid Phase Microextraction (HS-SPME) from the bacterial culture was conducted, followed by Gas Chromatography Mass Spectrometry (GC-MS). The chromatographic results revealed a high abundance of VOCs released just by culture media. Once, the difference between VOCs emitted by culture media and bacteria was established, it was possible to make a putative identification of 2-furanmethanol, phenylacetonitrile, and 2,4-dimethylpentanol as possible VOCs responsible for the antifungal activity.