bluuebunny/crossref_metadata_2025 huggingface dataset:
Reversal of Hepato-renal Impairment Induced by Meloxicam Paracetamol Toxicity in a Labrador Dog
Authors: Saravanan M. , Premalatha N. , Ramkumar P. K. , Kannan K. , Apoorva R. , Venkatesan M. , Jayalshmi K. , Yogeshpriya S. , Senthilkumar S.
Published: August 2023

An 8 years old male Labrador dog was referred to Small animal Medicine Referral Clinic, Veterinary Clinical complex, Veterinary College and Research Institute, Orathanadu for fever, anorexia, hematemesis and melenic stools. The dog on treatment with 2 ml of Meloxicam Paracetamol combination IM, along with Injection Oxytetracycline and fluid therapy for 3 days by locally and did not respond to treatment thus was referred. Clinical dullness, lethargy, respiratory distress, visible mucosal jaundice, ecchymosis on ventral abdomen was noticed. Physical examination revealed, halitosis, ulceration in the tip of the tongue, dehydration, pre scapular LN enlargement, distended abdomen, fluid thrill and splenomegaly. Hematology revealed anemia and thrombocytopenia. Biochemical analysis revealed Hyperbilirubinemia, Elevated BUN, Creatinine, AST, ALT, ALP and hypoalbuminemia. Abdominal ultrasound reveled splenomegaly, focal hyperechoic liver parenchyma, cortex echogenicity of right kidney and perirenal fluid accumulation. ECG revealed peaked T wave. Radiography revealed hepatosplenomegaly. Hemato-biochemical alteration was monitored before and after therapy. Animal was managed with fluid therapy, Acetylcysteine, Amino acid and supportives and the dog had an uneventful recovery.
Appraisal of Trace Elements and Heavy Metals Levels in Breast Cancer Patients of Basrah Province
Authors: Abdulhaleem Khalaf Eman , Abduljaleel Salwa A. , Majid Al-Jassani Hadeel
Published: August 2023

We know that metals are linked to a number of health problems such as constipation, abdominal pain, according to previous reports and lack of appetite, sickness, wakefulness, annoyance, irascibility, giddiness and encephalopathy. However, recent studies have found correlation between cancer and some toxic metals concentration in patients body. Most carcinogegenic metals are Cd, Pb and Hg. Objective: Current study was aimed to determine the concentrations of some metals(Cd, Pb, Hg, Cr, Cu and Zn) in whole blood, serum and hair of breast cancer patients in Basrah city, South of Iraq. Methods: Sample of whole blood, serum and hair were obtained from 60 breast cancer patients, the same samples were collected from 25 people without cancer as control group. Concentrations of heavy metals were carried out using ICP MS (an inductively coupled plasma atomic absorption spectrophotometer). Results: Concentrations of toxic metal such as Cd and Hg occurred at low level in three tissues while Zn occurred at higher concentrations. Pb concentration in the whole blood sample was 22.36 ug/l, Cr: 6.63, cu: 42.35.ug/g, serum of patients accumulating higher concentrations of Hg, Cr, Cu and Cd than in the whole blood sample. Even as Pb and Zn concentrations were high in whole blood. Conversely, hair sample of breast cancer patient accumulated significantly higher concentrations of Hg. Cr, Cu, Cd, Pb and Zn compared to other tissues. Positive correlations were recorded between Cd and Pb (r = 0.46), Zn with Cr, Cu and Hg (r = 0.78, 0.56, 0.88) respectively. Conclusion: High concentrations of Hg, Cr, Cu, Cd and Pb were detected in whole blood, serum and hair of breast cancer patients relative with other control group. Hair samples accumulated the high levels of Cd, Cu, Cr, Hg, Pb and Zn in comparison with whole blood and serum of breast cancer patients.
Chemical Composition and Evaluation of Methanol Leaf Extract of Combretum dolichopetalum on Body Weights and Haematological Indices of Phenylhydrazine Induced-anaemic Rats
Authors: Emelike Chinedum U. , Anyaehie Ugochukwu S. B. , Iyare Eghosa E. , Obike Chiemeziem A. , Aloke Chinyere , Chukwu Darlington F. , Eleazu Chinedum O. , Chukwu Chukwuma J. , Ekakitie Ofovwe O. , Konyefom Nwaeze G. , Uzomba Chinedu G. , Chukwu John A. O.
Published: August 2023

Anaemia is a serious health challenge in developing countries. This study evaluated the chemical composition of Combretum dolichopetalum (CD) leaves, the effect of its methanol extract on the body weights and haematological indices of phenylhydrazine induced-anaemic rats. Fresh matured leaves of CD were collected, identified and authenticated. Phytochemicals, proximate compositions, mineral elements, anti-nutritional factors and Gas Chromatography-Mass Spectrometry (GC-MS) analysis were determined. A total number of twenty (20) mature inbred apparently healthy male albino rats of the Wistar strain (100-150 g) were used for this study. Anaemia was induced by administering phenylhydrazine to rats in Groups 2, 3 and 4 comprising of five rats per group. Group 1 (non-anaemic control) (n = 5) and Group 2 (anaemic control) received distilled water respectively while Groups 3 and 4 were administered 200 and 400 mg/kg of CD leaf extract orally using oropharyngeal cannula once per day for 28 days. Blood samples were obtained for haematological analysis using standard methods. The result showed a significant increase in Red Blood Cell (RBC), Packed Cell Volume (PCV) and haemoglobin concentration in Groups 3 and 4 compared with the anaemic group. Chemical analysis showed the presence of some phytochemicals, proximate compositions, mineral elements and anti-nutritional factors. GC-MS analysis showed the presence of nine (9) compounds. This study indicates that CD is nutritionally rich and contains some important bioactive principles that support its anti-anaemic properties.
Predictors of Severity and Survival in Acute Cases of Organophosphorous Poisoning at Zagazig University Hospitals: Prospective Cohort Study
Authors: Eisa Hend S. , Nomier Mahmoud A. , Arafa Manar H. , El-Sayed Khayal Eman
Published: August 2023

Organophosphorous Insecticides (OPIs) have been profusely used and toxicity by them are common. Scoring systems are used as predictors of survival in severely ill patients. OPIs toxicity is associated with multiple biochemical abnormalities like changes in serum lactate. The aim of this study was evaluation the role of Acute physiology and chronic health evaluation II (APACHE II), Sequential Organ Failure Assessment (SOFA) scores, acetyl cholinesterase (AChE), and lactate enzymes in assessing severity, outcome and complications in acutely OPIs poisoned patients. This prospective cohort study was carried out on 36 OPIs poisoned patients admitted to Zagazig University Hospitals in seven months' period from the beginnings of May 2019 till the end of November 2019. The Peradeniya Organophosphorus Poisoning (POP), APACHE II and SOFA scores were calculated on the first day of admission. Serum lactate, and AChE enzymes were measured on admission and after 24 h. The cases were aged from 3 to 66 years old. As result of the study: APACHE II and SOFA scores were predictors of severity. The decrease in AChE level was correlated with the severity and complications but it was not predictor of them. Lactate was predictor of outcome and complications. Thus, APACHE II and SOFA scores can have used as predictors of severity. Also, lactate can be used as a predictor of outcome and complications.
Mimosa pudica Ameliorated Dichlorvos Induced Neuro-oxidation
Authors: Enye L. A. , Ebeye A. O. , Udi O. A. , Ishola A. O. , Igbigbi P. S.
Published: August 2023

There has been a drastic widespread use and abuse of dichlorvos (DDVP) with increasing accidental and intentional exposure. Hence, the need for a local therapeutic remedy before medical intervention. This study aimed to show the ameliorative properties of Mimosa pudica (MP) on DDVP induced neurotoxicity. 50 adult BALB/c mice were randomly divided into 5 groups of 10 mice each. Mice were given normal feed or poisoned feed (2.5% of dichlorvos in feed) with or without MP extract treatment. The exposure lasted for 28 days and all administration was done orally. At the end of exposure, mice were euthanized using chloroform and perfused transcardially using 1X PBS followed by 10% formal saline for animals designated for histochemical evaluations. Exposure to DDVP reduces granular cell layer thickness, altered Nissl substance distribution, elevates expression of GFAP and CD68 compared to control, co-administration with MP extract did not considerably reversed these effects unlike DDVP+MP that showed similar observation to control mice. GR was significantly high in all groups than the control except DDVP+MP and the level of SOD was significantly reduced in DDVP mice compared to other groups. DDVP induced hippocampal alterations accompanied by oxidative stress reversed by subsequent treatment with MP extract.
Effect of 2 Naphthalene Sulfonate on Biochemical Stress Markers as well as Structural Integrity of DNA in Liver and Kidney Tissue of Channa punctatus after Acute Exposure
Authors: Mehra Sukanya , Chadha Pooja
Published: August 2023

2Naphthalene Sulfonate (2NS) is an intermediate compound used in textile industries but being nonbiodegradable, the solicitude regarding its ecotoxicity has risen. Thus, an inquisition was undertaken with the objective of evaluating the oxidative stress and genotoxicity of 2NS in fresh water fish, Channa punctatus. Based upon calculated LC50 value, two sublethal doses were selected i.e. 2.38g/L and 4.77g/L for further investigation. In order to study acute effect of 2NS, liver and kidney samples were collected after 24h, 48h, 72h and 96h of exposure. Symbolic elevation in oxidative stress biomarkers and DNA damage was observed revealing the toxic impact of 2NS. The study would be helpful in assessing the risk impose by 2NS and calls for urgency in application of stringent policies against the indiscriminate use of such toxic compounds.
Potential of Zingiber officinale Extract against Chlorpyrifos Toxicity in Caprine Testicular Cells
Authors: Saraf Priyanka , Panchal Harish , Sharma Kameshwar , Sharma Sanjeev , Bhardwaj Jitender Kumar
Published: August 2023

Chlorpyrifos, an organophosphate insecticide, is currently under studies due to its reproductive toxicity in non-targeted organisms. The present study on its efficacy as reproductive toxicant, revealed its effect on testicular cells of caprines. CPF was found to decrease cell viability in testicular cells, induced histo-architectural alterations like loss of tubular interactions and empty luminal spaces in testis; initiated DNA damage associated apoptosis as revealed by MTT, Histology and EB/AO fluorescence assay respectively, at both the doses (10 and 50 μM). CPF mediated toxicity induced oxidative stress in testicular cells as revealed by dose- and time-dependent increase in lipid peroxidation and decline in ferric reducing antioxidant power. However, supplementation of Zingiber officinale (ginger) extract reduced the CPF mediated decrease in cell viability, histological defects, incidence of apoptosis, and generated oxidative stress parameters; thus, proving its potential as a therapeutic agent against CPF, preventing testicular cells toxicity mediated reproductive disorders.
Impact of Paraquat on Acid and Alkaline Phosphatase Activity in Indian Major Carp Cirrhinus mrigala Hamilton
Authors: Birajdar Nagesh Baliram , Bhilav Madhav Pralhad
Published: August 2023

Paraquat is a non-selective aquatic herbicide used to control nuisance vegetation in aquatic bodies. It potentially causes fish toxicity. The present investigation was undertaken to evaluate alterations in Acid Phosphatase (ACP) and Alkaline Phosphatase (ALP) activity in fingerlings of commercially important Indian Major Carp Cirrhinus mrigala. Both ACP and ALP are popular biomarkers of pesticide toxicity- induced aquatic pollution. 96 hours of acute exposure to LC0 and LC50 concentrations and 30 days of chronic exposure to LC1/20th and LC1/10th concentration of paraquat were studied during the present experiment in selected four tissues viz. gill, liver, muscle and brain to interpret its comparative impact at different effective concentrations on selected target tissues of fish. 30 days of chronic exposure to LC1/10th dose of paraquat showed exceptionally highly significant (p<0.001) decline in ACP activity of all four tissues among all other treatment groups when compared with the control. The liver tissue of fishes exposed to both the acute concentrations of paraquat shows an exceptionally highly significant (p<0.001) decrease in ALP activity among all other treatment groups and tissues when compared with control. From the present study, it can be concluded that paraquat-induced decline in ACP and ALP activity in Cirrhinus mrigala can be utilized as a prominent biomarker of aquatic toxicity induced due to pesticides in non-targeted organisms like fish. Paraquat can be potentially considered an aquatic ecosystem hazard leading to severe environmental pollution and eco-toxicity.
THE ROLE OF SAUDI UNIVERSITIES IN ENCOUNTERING ELECTRONIC EXTREMISM AMONG UNIVERSITY YOUTH FROM THE FACULTY MEMBERS' AND STUDENTS' POINTS OF VIEW
Authors: Azmi Zaki Abdelgwad Mervat
Published: August 2023

The current study aimed to identify the role of universities in raising awareness and preventing electronic extremism from the faculty members' and students' points of view. The results of the study demonstrated that the role of universities in addressing the problem of electronic extremism among university students from the views of points of faculty members and students was moderate. The fields of universities' role in addressing this phenomenon were achieved as follows: the field of the preventive role of universities in addressing the problem of electronic extremism among university students occupied the first rank within the medium average, the field of the awareness role of universities in addressing the problem of electronic extremism among university students occupied the second rank within the medium average, and the field of the educational role in addressing the problem of electronic extremism among university students was in the third rank within the medium average. The study concluded by presenting a suggested proposal to activate the preventive, awareness, and educational role of universities in confronting electronic extremism.
THE IMPORTANCE AND FACTORS AFFECTING THE ACCREDITATION OF VOCATIONAL EDUCATION QUALITY IN VOCATIONAL COLLEGES
Authors: Dang Nguyen LongAn
Published: August 2023

The development of education and vocational training is the cause and responsibility of the whole society, an essential content of the national human resource development strategy and planning; in which vocational colleges hold important positions and roles. In recent years, the network of vocational colleges has grown rapidly and widely throughout the country, the force of teachers and administrators as well as the number of trainees participating in vocational training has grown tremendously. With this development, accreditation of vocational education is a necessary requirement and plays an important role. A study of the State’s legal documents, the requirements of practice, and survey results on vocational education quality accreditation show that this activity plays an important role in developing vocational education. On the basis of survey and evaluation, combined with the regulations of the State, this study identifies the importance and the factors affecting the accreditation of vocational education quality in colleges, thereby recommending solutions to improve the quality of this activity in the future.
O pewnych walorach nie-dietetycznej ontologii: wyznanie nawróconego anty-ingardenisty
Authors: Jadacki Jacek
Published: August 2023

The main impulse for this considerations is a beautiful Professor Adam Nowaczyk's text "The
spell of Plato. Reflections on Roman Ingarden's ontology".
My general (negative) thesis is that no hyper-dietetic, i.e. monocategorial, ontology (meant
as the theory of real objects) is not correct. Thus neither the theory of sets (if it assumed the
uniqueness of the ontic category of sets), nor reism (if it assumed the uniquenes of the ontic
category of things) or eventism (if it assumed the uniqueness of the ontic category of events) are
correct ontologies (meant as theses on existence of a certain ontic category).
The consequence of this negative thesis is that only non-dietetic, i.e. polycategorial, ontology
can be correct.
I present a few arguments on account of theses two theses.
Crop Weather Pest Relationship and Forewarning Model for Spodoptera frugiperda on Maize and Sorghum
Authors: Prathima T. , Sudheer K.V.S. , Devaki K. , Madhuri C.V. , Subramanyam G. , Aggile Lakshmiprasanna
Published: August 2023

Background: Fall Armyworm, Spodoptera frugiperda is a crop pest with over 80 host species that causes severe damage to maize and sorghum crops. S. frugiperda is native to tropical and subtropical region of America that has spread rapidly throughout the world. Methods: Based on the severity of S. frugiperda in India a field experiment was conducted to study the pest influence in maize and Sorghum crops for two years i.e., 2020 and 2021 during the kharif season at Regional Agricultural Research Station, Tirupati. Using correlation and regression techniques, the data was pooled and statistically analysed with weather parameters. Result: Correlation studies revealed a significant positive relationship between pest damage and minimum temperature showed negative relation with morning and evening relative humidity, while wind velocity and evaporation are positively influenced S. frugiperda damage. Maximum temperature, wind velocity and evaporation together played a role in the occurrence of S. frugiperda. Regression equations were developed using SPSS for predicting the damage caused by S. frugiperda.
Incorporating role-play as an innovative approach to fostering English Foreign Language students’ creativity and critical thinking
Authors: Elouali Fatima zohra
Published: August 2023

Communicative activities introduce learners to real-life situations that require speaking in the target language. As a didactic strategy, role-play is assumed to be an effective method of learning and developing social skills, creativity, critical thinking, problem-solving, and communication using simulated scenarios. In the present investigation, role-playing is used in an educational setting specifically in English foreign language classes. This research paper sheds light on the importance of including innovative approaches when teaching; moreover, it investigates the impact of role-plays in developing speaking qualifications, social knowledge, and personal skills. The sample comprised 35 EFL students at the University of Ain Temouchent, Algeria. To guarantee research validity and reliability, a mixed methods approach was applied to collect and analyze data. The findings demonstrate that students could increase their speaking qualifications and overcome speaking difficulties and using role-plays can develop students’ creativity and critical thinking by engaging them in real-life situations.
Keywords: Communicative skills; creativity; critical thinking; role-plays; speaking qualifications.
D. I. Mendeleev’s Yu. periodic law, G. Shcherbakov’s cosmogeochemical system and prospects for the development of mineralogical and geochemical investigations
Authors: Kokin A. , Silaev V. , Kokin M. , Khazov A.
Published: August 2023

The law of cosmogeochemical differentiation discovered by the remarkable Russian geochemist Yu. G. Shcherbakov and the geochemical classification of elements formulated on its basis on the scale of the Periodic system of D. I. Mendeleev are analyzed. Based on new research results, it is shown that signs of the fundamental cosmic distribution code of chemical elements are quite clearly preserved in terrestrial geological and biological objects.
Frustrating Times: Notes from the Field
Authors: Jones Stephanie
Published: August 2023

Business Law Clinics’ involvement in advising Small and Medium Sized Enterprises (SMEs) reached an interesting crescendo during the pandemic as businesses were often left high and dry by business customers and suppliers who could or would not fulfil their contractual obligations. SMEs, often sole traders or limited companies with no business premises, found themselves unable to access government support and facing insolvency. Many had no contracts in place, or they sought to rely on their terms and conditions of business only to find them lacking due to reasons grounded in law (there is no freestanding concept of force majeure under English law and if a contract is silent on it, English law will not imply it) or process (lack of incorporation of terms through their own fault). In this note I seek to examine the impact of the pandemic on the concept of force majeure and contractual remedies for SMEs in the UK and to contemplate the role of business law clinics in advising SMEs on the use of terms and conditions in business-to-business (B2B) contracts as part of successful operations in the post-Covid world. Drafting sets of terms and conditions for SME clients is a perfect vehicle for meeting the goals of a university business law clinic – community engagement with local SMEs providing them with fast, tailored advice with a bespoke tangible document to take away plus student experience of real- world learning in commercial law (experience which is not always readily available for students outside the big cities).
Thinking Like Entrepreneurs: Qlegal’s Experience of Teaching Law Students to have an Entrepreneurial Mindset
Authors: Platts-Mills Eliza , Wapples Emily
Published: August 2023

To advise a client you need to understand what they do. To provide truly innovative, client-centred advice, you also need to understand how they think. These observations are especially true when working with entrepreneurs who may be otherwise inclined to move forward with their business with or without legal guidance.
Entrepreneurs are distinguished by their growth mindset and resilience, appetite for innovation and comfort with taking risks and doing things themselves. As the legal marketplace in the UK becomes increasingly competitive (due to legal technology and the growing number of alternative legal service providers), law students need to adopt an entrepreneurial mindset themselves, both to navigate the legal marketplacefor their own careers and to provide commercially aware legal services to their clients. Law schools need to teach law students to think like entrepreneurs, and commercial law clinics provide the natural setting.
This paper adopts a qualitative case study approach to examine how qLegal, the pro bono commercial law clinic within the Centre for Commercial Law Studies (“CCLS”) at Queen Mary, University of London (“QMUL”) teaches students to develop an entrepreneurial mindset. We reflect on the importance of students learning about and developing this mindset, for their own professional development and to service the unmet legal needs of the start-up community. This paper will also highlight the challenges faced by qLegal staff, including our own legal training and experience, our obligations to real clients and our students’ expectations. We conclude by sharing examples of how we are currently teaching our students to have an entrepreneurial mindset and our ideas for overcoming our institutional challenges and improving our offering even more.
The Resource Implications of Work Integrated Learning and Legal Clinics in Australian Legal System: Managing Workload, System Support and Recognition
Authors: Hewitt Anne , Skead Natalie
Published: August 2023

Work integrated learning (WIL) has been embraced as a valuable pedagogy by many Australian law schools, which offer students the opportunity to engage in a variety of WIL including clinical legal education, placements in law firms and industry projects. However, there is widespread recognition that WIL pedagogies have unique resourcing requirements in terms of workload and infrastructure. In addition, there is evidence that academic contribution to WIL pedagogies is not positively regarded in the context of academic advancement. This article explores the resources required to deliver legal WIL and presents novel data about how this is being accommodated by Australian law schools. This analysis informs the development of specific recommendations for Australian law schools on the resourcing of legal WIL.
PERANCANGAN SISTEM INFORMASI LAYANAN JASA KACA FILM BERBASIS WEB PADA PT. V-KOOL INDO LESTARI
Authors: Sari Reina Azmi , Wanda Sulistianto Sutrisno
Published: August 2023

Perancangan sistem informasi layanan ini merupakan salah satu solusi untuk menyelesaikan permasalahan proses kerja dengan ˇmemanfaatkan kemajuan teknologi dan informasi. Pilih metode pengembangan sistem yang efektif dan efisien untuk membantu pelanggan Anda merespons kebutuhan mereka secara instan. Pencatatan transaksi tidak terkomputerisasi dan proses pengumpulan informasi lambat karena PT V-KOOL Indo Lestari sendiri menggunakan cara manual. Menyelesaikan masalah ini membutuhkan inovasi yang sesuai, seperti pengembangan sistem informasi berbasis web. Penelitian ini bertujuan untuk mengetahui pengaruh kualitas layanan, kualitas produk terhadap kepuasan pelanggan dan loyalitas pelanggan. Peneliti mencoba untuk memprediksi apakah pelanggan akan tetap setia kepada perusahaan. Oleh karena itu, kualitas layanan berpengaruh besar terhadap kepuasan pelanggan, kualitas produk berpengaruh besar terhadap kepuasan pelanggan, hubungan kepuasan pelanggan berpengaruh besar terhadap loyalitas pelanggan, dan kualitas layanan berpengaruh besar terhadap pelanggan. Berdasarkan hasil survey di atas, maka sebaiknya dibuat proposal yang mengutamakan kualitas pelayanan dan kualitas produk. Metodologi yang diperlukan terdiri dari proses penelitian pengguna untuk menganalisis dan mengimplementasikan sistem. Hasil analisis dideskripsikan dengan menggunakan bahasa pemodelan UML (Unified Modeling Language).
COBIT 5: EVALUATION OF IT GOVERNANCE AT BANK X
Authors: Akmalia Gina , Wella Wella , Suryasari Suryasari
Published: August 2023

The role of information technology has become a very important part of the companies or institutions that enterprise scale. The company puts information technology as a matter that can support the company's strategic plan to achieve the target's vision, mission, and goals. For banking companies, in running the business can not be separated with the role of technology. The object of this research is the IT Division at PT. Bank X, the study uses framework COBIT 5.0. The method is uses stages of Hunton (2004), which consists of seven stages: planning, risk assessment, development of audit programs, gather evidence, form conclusions, prepare the audit opinion, and follow-up. The variables of this research is the process of manage changes and it reactions in the domain Build, Acquire, and Implement (BAI). BAI06 related to manage changes and BAI07 related to acceptance change and transition. Data collection was done by interviewing with the IT department and IT Internal Audit, distributed questionnaires to the Division of IT and IT Internal Audit, and observing documents. The interviews has done for four times and the total questionnaire prepared is 155 questions questionnaire include level one to five. Results of this research are the process BAI06 at level two (Managed) with an average score at level three at 83.46% while for BAI07 process at level three (Established) with an average score at level four at 59, 50%.
Perkembangan Penyebab Penyakit Busuk Lunak Pada Tanaman Buah Naga Merah (Hylocereus Polyrhizus) di Kabupaten Banyuwangi
Authors: Hantoko Denis ardwi hantoko Ardwi , Dwi Nur Cahyani Suhartiningsih
Published: August 2023

Red dragon fruit (Hylocereus polyrhizus) is one of the most important commodities in Indonesia. The dragon fruit production center in Indonesia is located in Banyuwangi Regency with a production of 82,544 per year. Areas in Banyuwangi that produce large quantities of dragon fruit are Bangorejo, Pesanggaran, Silirangung, Purwoharjo, and Tegaldlimo. Dragon fruit is a type of plant that has a strong resistance, but there are many factors that can cause a decrease in production, one of which is OPT. Soft rot disease in dragon fruit is an example of a pest that attacks dragon fruit plants. This disease can cause physical, physiological, and chemical changes in dragon fruit plants that affect production yields. According to several sources of bacteria that cause soft rot disease is Pectobacterium. Pectobacterium will spread quickly if the surrounding conditions are supportive, such as environmental conditions, weather, temperature, and care carried out by farmers.
Suboptimal ovaryen yanıtta POSEIDON grup 1b ve 2b hastaların in vitro fertilizasyon sonuçları: Retrospektif analiz
Authors: KESKİN Müge , ATİK Ahmet , ÇAĞLAR Gamze Sinem
Published: August 2023

Amaç: Hastalar, over rezerv testlerinde yola çıkarak; ovaryen stimülasyona (OS) zayıf, normal veya aşırı yanıt vermesi beklenenler olarak sınıflandırılır. Hastaları zayıf, normal ve aşırı yanıt verenler olarak üç kategoriye ayırmanın, yeterliliği sorgulanmaktadır ve suboptimal (beklenenin altında) yanıt verenlerin ayrı bir grup olarak dahil edilmesi önerilmektedir. Suboptimal yanıt verenler, OS sonrası 4’ten az oosit toplanan zayıf ve 10-15 arası oosit toplanan normal yanıt verenler arasındaki gruptur. Bu hastalardan 4-9 arası oosit toplanır ve POSEIDON sınıflamasına göre grup 1b-2b’yi (PG 1b-2b) oluşturur. Çalışmamızın amacı PG 1b-2b hastaların IVF (in vitro fertilzasyon) sonuçlarını normal yanıt verenlerle karşılaştırmaktır.

Gereç Yöntem: Bu çalışmada, bir IVF kliniğinde retrospektif data analizi yapıldı. Normal yanıt verenlerle (yeterli over rezervine sahip ve ≥9 oosit toplanan) ve PG 1b-2b kadınların (yeterli over rezervine sahip standart OS sonrası 4-9 arası oosit toplanan, sırasıyla
Melanoma de mucosa vulvar: relato de caso
Authors: Gomes Adriana de Menezes , Dias Vinicius Quintanilha Gomes , Themótheo Florice de Matos , Nunes Paulo Henrique Silva , Leal Renato Mazon Lima Verde , Araújo Filho Irapuan Teles de , Goes Annya Costa Araújo de Macedo
Published: August 2023

Introdução: Melanoma de mucosa é uma doença rara que corresponde a aproximadamente 0,03% de todos os diagnósticos de câncer e 1.4% de todos os tipos de melanoma e representa aproximadamente 10% de todos os tumores malignos da região vulvar. Metodologia: Revisão do prontuário de paciente internada nesta Instituição no período de setembro de 2021, com revisão de literatura a partir de dados da base PUBMED. Relato: Paciente, 36 anos, com relato de lesão hiperpigmentada em região interna de grande lábio há 10 anos com mudança de comportamento há 4 meses. Apresentava nodulação no local associada a dor e saída de secreção serossanguinolenta/purulenta. Após biópsia excisional e confirmado achado de melanoma de mucosa vulvar em anatomopatológico, foi constatado ao exame físico presença de linfonodo palpável com características suspeitas de metástase. Assim, realizou-se tomografia para estadiamento, cirurgia de ampliação de margens cirúrgicas e linfadenectomia inguinal esquerda. Confirmado o comprometimento linfonodal, a paciente foi encaminhada para radioterapia. Conclusão: Melanoma de mucosa é uma doença rara de prognóstico reservado. Devido ao seu diagnóstico mais tardio, tem elevadas taxas de metástase já no estadiamento inicial. Faz-se importante estudos adicionais para esclarecimento da doença e proposta de terapêuticas eficazes no aumento da sobrevida geral.
Identifikasi Faktor-faktor yang mempengaruhi Persentase Penduduk Miskin di Provinsi Jawa Tengah dan D. I. Yogyakarta
Authors: Viryanto Ferdy Agus
Published: August 2023

Kemiskinan menjadi salah satu dampak dari krisis global. Di bandingkan tahun 2020, persentase penduduk miskin mengalami penurunan sebesar 0.48% pada tahun 2021. Selain pengaruh pandemi Covid-19, faktor lain dapat berpengaruh terhadap persentase penduduk miskin. Faktor tersebut dapat di identifikasi menggunakan regresi data panel dengan model fixed effect dan metode ordinary least square. Data terdiri dari 35 kabupaten/kota di Jawa Tengah dan 5 kabupaten/kota di Yogyakarta dari tahun 2019-2021. Hasil menunjukkan bahwa rata-rata lama sekolah dan umur harapan hidup berpengaruh positif dan signifikan, sedangkan tingkat pengangguran terbuka dan produk domestik regional bruto berpengaruh negatif, tetapi tidak signifikan terhadap persentase penduduk miskin. 99.71% variabilitas dalam persentase penduduk miskin dapat dijelaskan oleh keempat faktor tersebut. Pendidikan, kesehatan, dan ketenagakerjaan dari faktor sosial serta pertumbuhan ekonomi dari faktor ekonomi perlu menjadi perhatian utama dalam menjaga kekuatan sosio-ekonomi Indonesia dalam menghadapi masalah kemiskinan sebagai dampak krisis global.
Peramalan Jumlah Pengguna Baru yang Terdaftar di Aplikasi iPusnas Menggunakan Metode Extreme Learning Machine
Authors: Mulyaningsih Anisa Dwi Mulyaningsih , Mujiati Dwi Kartikasari
Published: August 2023

Perpustakaan merupakan salah satu komponen yang berperan penting dalam penyediaan buku-buku sebagai sumber acuan pembelajaran. Kecenderungan membaca teks elektronik terus meningkat dari hari ke hari. Seiring dengan perkembangan zaman yang semakin pesat membuat terciptanya layanan perpustakaan online untuk memudahkan pembaca menikmati layanan buku gratis dimanapun berada. Untuk itu iPusnas merupakan salah satu layanan perpustakaan online yang harus dikembangkan dengan sebaik mungkin. Berdasarkan perkembangan zaman yang semakin pesat mengenai perpustakaan digital, pemerintahan perlu mengetahui landasan untuk melakukan pengembangan pada aplikasi layanan perpustakaan online menjadi lebih baik. Dengan demikian perlunya dilakukan metode prediksi Extreme Learning Machine (ELM) dengan menggunakan analisis data historis yang berguna untuk menentukan perkembangan di masa depan. Penelitian ini bertujuan untuk mengetahui nilai dari hasil analisis menggunakan metode Extreme Learning Machine untuk mendapatkan prediksi pengguna baru di aplikasi perpustakaan digital yaitu iPusnas pada bulan April hingga bulan Desember 2021. Studi kasus yang digunakan dalam penelitian ini adalah data pengguna baru iPusnas pada bulan Januari 2017 hingga bulan Desember 2021. Kemudian hasil yang diperoleh dari penelitian ini yaitu nilai Mean Absolute Percentage Error (MAPE) sebesar 22.69949%.
Rare Editions of N. M. Karamzin’s Works in Novosibirsk Libraries
Authors: Dragaikina T. A.
Published: August 2023

Lifetime and rare editions of works of great writers, researchers, public figures are of special cultural and historical value and enjoy the increased attention of the keepers of book collections and visitors of book museum exhibitions. The purpose of this article is to introduce into scientific circulation the rare copies of domestic and foreign editions of works of the historian and writer N. M. Karamzin (1766 – 1826), stored in the Novosibirsk State Regional Scientific Library (NSRSL) and the State Public Scientific and Technological Library of the Siberian Branch of the Russian Academy of Sciences (SPSTL SB RAS). Among them are books from the library of the Kolyvan-Voskresensk mining plants, including those received there from personal collections of mining engineers, copies of the journal “Vestnik Evropy” for 1802-1803 from the collection of V. S. Mikhalkov, a volume of “History of the Russian State” used in one of the oldest educational institutions in Russia – the Smolensk Boys’ Gymnasium, a volume of a lifetime edition of the “History of the Russian State”, which belonged to the historian, archaeographer P. M. Stroev, the compiler of the “Key, or alphabetical index to the “History of the Russian State” by N. M. Karamzin”.Special attention should be paid to the first complete Russian-language edition of “On Ancient and New Russia in its Political and Civil Relations”, written in 1811, addressed directly to Emperor Alexander I and for censorship reasons first published only abroad, in Berlin, in 1861. A copy from the Department of Rare Books and manuscripts of the State Public Scientific Library of SB RAS is unique in that it contains proofreading notes of the historian A. N. Pypin. Relying on this copy of the Berlin edition of N. M. Karamzin’s work and consulting the handwritten copies of it which were at his disposal, he prepared the first complete publication of the text of this manifesto of Russian conservatism in Russia in 1900 as an appendix to his monograph “Social Movement in Russia under Alexander I”. A careful study of valuable publications from the collections of Novosibirsk libraries deepens our knowledge about the book culture of Siberia and, more broadly, about the history of Russian-language book culture, about the history of the formation of Novosibirsk book collections, demonstrates the continuity of these collections in relation to the outstanding book collections of the past.
The Memorial Electronic Information Resource Dedicated to the Baikal Researcher M. M. Kozhov
Authors: Kustova E. M. , Trofimov I. L. , Barash S. M.
Published: August 2023

Scientific libraries are intermediaries between science and society; they concentrate scientific and popular scientific information for a wide range of users. The information block: science – library – society works. Libraries solve the issues of book preservation, documentary, archival heritage of scientists through various forms of preservation and popularization of the achievements of regional science: work with the rare collection of scientific publications (study of marks, book plates, autographs, etc. on books), publication of articles about scientists, creation of bibliographic and biographic databases (DB) and other electronic information publications of own generation.Communicative interaction between libraries, science and society is constantly expanding, including various new components of the popularization of science among young people than attract young people to science and cause interest in the profession of a scientist. The article describes the work of the Central Scientific Library of the Irkutsk Scientific Center of the Siberian Branch of RAS in this direction on the example of the organization of electronic memorial library of Baikal scientist, Professor Mikhail Mikhailovich Kozhov.
Library and Information Activity on Promoting Historical and Cultural Heritage Among the Youth
Authors: Zhukovskaya L. N.
Published: August 2023

The article defines the main directions of library and information activities to popularize the historical and cultural heritage among the youth; the problems of cultural values influence on the spiritual and moral development of young people are considered. It is stated that in working with youngsters to promote the historical and cultural heritage of Russia, traditional and innovative forms of enlightenment and educational practices remain in demand. The mechanisms for promoting cultural values of the country in the educational, cultural and leisure activities of library institutions are revealed on the example of the State Universal Scientific Library of the Krasnoyarsk Territory. The experience of the regional library in the implementation of social and cultural projects aimed at forming the national and civic identity of young people is reflected. It is indicated that the socio-cultural design of the library is a unique technology that can systematically perform operations and procedures, ensure the reliability of results, and the flexibility of implementation. The features of the organization of project activities are highlighted - information, consulting and subscription services, information support for self-education of participants in each project. The creation in the library of the historical and cultural space “The Book Heritage of Krasnoyarsk”, which during the project contributed to the convergence of the value orientations of young people and older people, made it possible to use diverse innovative forms of promoting cultural and historical heritage. It is noted that the library projects helped to convey to the youth the cultural traditions of the peoples of Russia, the Krasnoyarsk Territory, brought the organization of educational events to upgrade the book culture to a higher qualitative level, created conditions for the use of modern technologies. Project initiatives result in the library becoming a powerful tool for the cultural and reproductive activities of young people in mastering the most important achievements of Russian culture through access to information resources, the main component of which is the book.
Rlc Electrical Modelling of Black Hole and Early Universe. Generalization of Boltzmann’s Constant in Curved Space-Time
Authors: Flores Hector Gerardo
Published: August 2023

Here we mathematically model black holes and the early universe following dynamics similar to RLC electrical models, focusing on their similarities at the singularity. We use this mathematically modelling to hypothesize the evolution of an expanding universe as the result of a black hole collapse followed by its evaporation. Or model consists of several steps defined by: (1) the formation of a black hole following general relativity equations; (2) growth of the black hole modelled as a resistance-capacitance-like electrical circuit; (3) expansion of space-time following the disintegration of the black hole, modelled by RLC-like dynamics. In updating this article, version 2, we will expand by presenting three additional examples related to the theory of the generalization Boltzmann's constant in curved space-time and the theory of general and especial relativity. We will calculate the critical mass to produce a black hole in the LHC, the existence of a high temperature Bose-Einstein condensate and finally we will demonstrate the existence of a tangential force to the repulsion force in the disintegration of subatomic particles. In the update of this article, version 3, we will expand to develop two examples. First, we will present the relationship between M-theory, extra dimensions with the theory of the generalization of Boltzmann's constant in curved space-time. Secondly, we will propose the idea of ​​updating the Lambda-CDM model, considering the primordial gravitational waves to correctly describe the evolution of the universe.
Efficient and Stable Air-Processed Ternary Organic Solar Cells Incorporating Gallium-Porphyrin as Electron Cascade Material
Authors: Soultati Anastasia , Verouti Maria , Polydorou Ermioni , Armadorou Konstantina Kalliopi , Georgiopoulou Zoi , Palilis Leonidas C , Karatasios Ioannis , KILIKOGLOU VASSILIS , Chroneos Alexander , Coutsolelos Athanassios G. , Argitis Panagiotis , Vasilopoulou Maria
Published: August 2023

Two gallium porphyrins, a tetraphenyl GaCl porphyrin, termed as (TPP)GaCl, and an octaethylporphyrin GaCl porphyrin, termed as (OEP)GaCl were synthesized to use as electron cascade in ternary organic bulk heterojunction films. A perfect matching of both gallium porphyrins energy levels with that of poly(3-hexylthiophene-2,5-diyl) (P3HT) or poly[N-9′-heptadecanyl-2,7-carbazole-alt-5,5-(4′,7′-di-2-thienyl-2′,1′,3′-benzothiadiazole)] (PCDTBT) polymer donor and the 6,6-phenyl C71 butyric acid methyl ester (PCBM) fullerene acceptor forming an efficient cascade system that could facilitate electron transfer between donor and acceptor was demonstrated. Therefore, ternary organic solar cells (OSCs) using the two porphyrins in various concentration were fabricated, where a performance enhancement was obtained. In particular, (TPP)GaCl-based ternary OSCs of low concentration (1:0.05 vv%) exhibited a ~17 % increase of the power conversion efficiency (PCE) compared with the binary device due to improved exciton dissociation, electron transport and reduced recombination. On the other hand, ternary OSCs with the (TPP)GaCl of high concentration (1:0.1 vv%) and (OEP)GaCl (1:0.05 and 1:0.1 vv%) showed poorest efficiencies due to very rough nanomorphology and suppressed crystallinity of ternary films when the GaCl porphyrin introduced in the blend, as revealed from X-ray diffraction (XRD) and atomic force microscopy (AFM). The best performed devices exhibited also improved photostability, when exposed to sunlight illumination for a period of 8 h than the binary OSCs, attributed to the suppressed photodegradation of the ternary (TPP)GaCl 1:0.05-based photoactive film.
Cyclic Load Impact Assessment on Long-Term Properties to Steel and PVA Fibre Reinforced Geopolymer Composites
Authors: Gailitis Rihards , Sprince Andina , Łach Michał , Gavrilovs Pavels , Pakrastins Leonids
Published: August 2023

This study investigates the cyclic load application impact on fly ash-based geopolymer composites that are reinforced with a low amount of fibre reinforcement. For reinforcement purposes, PVA and steel fibres are used. For testing purposes, four geopolymer composite mixes were made, 3 of which had fibre reinforcement. Simultaneously specimens were tested for shrinkage, static load-induced creep, and cyclic load-induced creep. For static and cyclic creep testing, specimens were loaded with 20% of their strength. For cyclic creep testing, load application and release cycles were seven days long. When each cycle was introduced, the load was added in steps. In 5 minutes, by 25% steps of the necessary load, the specimens were loaded or unloaded. Only plain specimens show that static creep strains are within cyclic creep strains. For all the other specimens, the static load is higher than the cyclic load-induced creep amplitude. Also, 1% PVA fibre-reinforced specimens show the most elastic characteristics under cyclic load, and 1% steel fibre-reinforced specimens appear to be the most resistant to the cyclic load introduction.
Mutual Inductance and Load Identification of LCC-S IPT System Considering Equivalent Inductance of Rectifier Load
Authors: Shen Haomin , Wang Xiaona , Sun Pan , Wang Lei , Liang Yan
Published: August 2023

The variation of mutual inductance and load parameters will affect the transmission power and efficiency of the inductive power transfer (IPT) system. The identification of mutual inductance and load parameters is an essential part of establishing a stable and reliable IPT system. This paper presents a joint identification method of load and mutual inductance for LCC-S IPT system, which does not require the establishment of primary and secondary communication and related control. Firstly, the resistance-inductance characteristics of the equivalent load of the rectifier are analyzed by simulation, and then the rectifier and system load are equivalent to the circuit model of resistance and inductance in series. Secondly, the characteristics of the reflected impedance are analyzed, and the functional relationship between the transmitter impedance and the rectifier impedance is established by using the ratio of the real part to the imaginary part of the reflected impedance, which realizes the decoupling of the load and the mutual inductance. Thirdly, the functional relationship between the equivalent impedance of the rectifier and the load resistance of the system is obtained by data fitting. Then, the equations of the above two functional relationships are combined. By measuring the voltage of the parallel compensation capacitor at the transmitting side, the current of the transmitting coil and the phase difference between the two, the battery load can be solved first, and then the mutual inductance can be calculated, so that the high-precision identification of the load and mutual inductance can be realized. Finally, an experimental platform of LCC-S IPT system is built for experimental verification. The experimental results show that the maximum identification errors of mutual inductance and load are 5.20 % and 5.53 %, respectively, which proves that the proposed identification method can achieve high precision identification.