bluuebunny/crossref_metadata_2025 huggingface dataset:
Shedding light on cell compartmentation in the candidate phylum Poribacteria by high resolution visualisation and transcriptional profiling
Authors: Jahn Martin T. , Markert Sebastian M. , Ryu Taewoo , Ravasi Timothy , Stigloher Christian , Hentschel Ute , Moitinho-Silva Lucas
Published: October 2016

Assigning functions to uncultivated environmental microorganisms continues to be a challenging endeavour. Here, we present a new microscopy protocol for fluorescencein situhybridisation-correlative light and electron microscopy (FISH-CLEM) that enabled, to our knowledge for the first time, the identification of single cells within their complex microenvironment at electron microscopy resolution. Members of the candidate phylum Poribacteria, common and uncultivated symbionts of marine sponges, were used towards this goal. Cellular 3D reconstructions revealed bipolar, spherical granules of low electron density, which likely represent carbon reserves. Poribacterial activity profiles were retrieved from prokaryotic enriched sponge metatranscriptomes using simulation-based optimised mapping. We observed high transcriptional activity for proteins related to bacterial microcompartments (BMC) and we resolved their subcellular localisation by combining FISH-CLEM with immunohistochemistry (IHC) on ultra-thin sponge tissue sections. In terms of functional relevance, we propose that the BMC-A region may be involved in 1,2-propanediol degradation. The FISH-IHC-CLEM approach was proven an effective toolkit to combine -omics approaches with functional studies and it should be widely applicable in environmental microbiology.
Air exposure of coral is a significant source of dimethylsulfide (DMS) to the atmosphere
Authors: Hopkins Frances E. , Bell Thomas G. , Yang Mingxi , Suggett David J. , Steinke Michael
Published: October 2016

Corals are prolific producers of dimethylsulfoniopropionate (DMSP). High atmospheric concentrations of the DMSP breakdown product dimethylsulfide (DMS) have been linked to coral reefs during low tides. DMS is a potentially key sulfur source to the tropical atmosphere, but DMS emission from corals during tidal exposure is not well quantified. Here we show that gas phase DMS concentrations (DMSgas) increased by an order of magnitude when three Indo-Pacific corals were exposed to air in laboratory experiments. Upon re-submersion, an additional rapid rise in DMSgas was observed, reflecting increased production by the coral and/or dissolution of DMS-rich mucus formed by the coral during air exposure. Depletion in DMS following re-submersion was likely due to biologically-driven conversion of DMS to dimethylsulfoxide (DMSO). Fast Repetition Rate fluorometry showed downregulated photosynthesis during air exposure but rapid recovery upon re-submersion, suggesting that DMS enhances coral tolerance to oxidative stress during a process that can induce photoinhibition. We estimate that DMS emission from exposed coral reefs may be comparable in magnitude to emissions from other marine DMS hotspots. Coral DMS emission likely comprises a regular and significant source of sulfur to the tropical marine atmosphere, which is currently unrecognised in global DMS emission estimates and Earth System Models.
Serological and molecular epidemiology of canine adenovirus type 1 in red foxes (Vulpes vulpes) in the United Kingdom
Authors: Walker David , Fee Seán A. , Hartley Gill , Learmount Jane , O’Hagan Maria J. H. , Meredith Anna L. , de C. Bronsvoort Barend M. , Porphyre Thibaud , Sharp Colin P. , Philbey Adrian W.
Published: October 2016

Canine adenovirus type 1 (CAV-1) causes infectious canine hepatitis (ICH), a frequently fatal disease which primarily affects canids. In this study, serology (ELISA) and molecular techniques (PCR/qPCR) were utilised to investigate the exposure of free-ranging red foxes (Vulpes vulpes) to CAV-1 in the United Kingdom (UK) and to examine their role as a wildlife reservoir of infection for susceptible species. The role of canine adenovirus type 2 (CAV-2), primarily a respiratory pathogen, was also explored. In foxes with no evidence of ICH on post-mortem examination, 29 of 154 (18.8%) red foxes had inapparent infections with CAV-1, as detected by a nested PCR, in a range of samples, including liver, kidney, spleen, brain, and lung. CAV-1 was detected in the urine of three red foxes with inapparent infections. It was estimated that 302 of 469 (64.4%) red foxes were seropositive for canine adenovirus (CAV) by ELISA. CAV-2 was not detected by PCR in any red foxes examined. Additional sequence data were obtained from CAV-1 positive samples, revealing regional variations in CAV-1 sequences. It is concluded that CAV-1 is endemic in free-ranging red foxes in the UK and that many foxes have inapparent infections in a range of tissues.
Conformity cannot be identified based on population-level signatures
Authors: Acerbi Alberto , van Leeuwen Edwin J. C. , Haun Daniel B. M. , Tennie Claudio
Published: October 2016

Conformist transmission, defined as a disproportionate likelihood to copy the majority, is considered a potent mechanism underlying the emergence and stabilization of cultural diversity. However, ambiguity within and across disciplines remains as to how to identify conformist transmission empirically. In most studies, a population level outcome has been taken as the benchmark to evidence conformist transmission: a sigmoidal relation between individuals’ probability to copy the majority and the proportional majority size. Using an individual-based model, we show that, under ecologically plausible conditions, this sigmoidal relation can also be detected without equipping individuals with a conformist bias. Situations in which individuals copy randomly from a fixed subset of demonstrators in the population, or in which they have a preference for one of the possible variants, yield similar sigmoidal patterns as a conformist bias would. Our findings warrant a revisiting of studies that base their conformist transmission conclusions solely on the sigmoidal curve. More generally, our results indicate that population level outcomes interpreted as conformist transmission could potentially be explained by other individual-level strategies, and that more empirical support is needed to prove the existence of an individual-level conformist bias in human and other animals.
A Novel Broadband Band-pass Filter Based on Spoof Surface Plasmon Polaritons
Authors: Zhao Lei , Zhang Xin , Wang Jun , Yu Wenhua , Li Jiandong , Su Hai , Shen Xiaopeng
Published: October 2016

In this paper, we present a novel broadband bandpass filter based on spoof surface plasmon polaritons (SSPPs) in the microwave frequency band. The proposed bandpass filter includes three parts: (1) coplanar waveguide (CPW); (2) matching transition; and (3) coupled structure that is an asymmetric coupled filter constructed by five grooved strips. The proposed bandpass filter realizes excellent low loss performance from 7 to 10 GHz, in which its insertion loss is around 1.5 dB in the same frequency band. Meanwhile, this filter has a good band stop characteristic from 3 to 7 GHz. A simple but accurate transmission line model was proposed to evaluate the proposed broadband SSPPs filter. The measured data, simulated results and the results obtained from the transmission line model have shown a very good agreement. The proposed planar broadband filter plays an important role for filtering surface plasmon polaritons (SPPs) waves in plasmonic circuits and systems.
Compact and Thermosensitive Nature-inspired Micropump
Authors: Kim Hyejeong , Kim Kiwoong , Lee Sang Joon
Published: October 2016

Liquid transportation without employing a bulky power source, often observed in nature, has been an essential prerequisite for smart applications of microfluidic devices. In this report, a leaf-inspired micropump (LIM) which is composed of thermo-responsive stomata-inspired membrane (SIM) and mesophyll-inspired agarose cryogel (MAC) is proposed. The LIM provides a durable flow rate of 30 μl/h · cm2 for more than 30 h at room temperature without external mechanical power source. By adapting a thermo-responsive polymer, the LIM can smartly adjust the delivery rate of a therapeutic liquid in response to temperature changes. In addition, as the LIM is compact, portable, and easily integrated into any liquid, it might be utilized as an essential component in advanced hand-held drug delivery devices.
Jolkinolide B induces apoptosis and inhibits tumor growth in mouse melanoma B16F10 cells by altering glycolysis
Authors: Gao Caixia , Yan Xinyan , Wang Bo , Yu Lina , Han Jichun , Li Defang , Zheng Qiusheng
Published: October 2016

Most cancer cells preferentially rely on glycolysis to produce the energy (adenosine triphosphate, ATP) for growth and proliferation. Emerging evidence demonstrates that the apoptosis in cancer cells could be closely associated with the inhibition of glycolysis. In this study, we have found that jolkinolide B (JB), a bioactive diterpenoid extracted from the root of Euphorbia fischeriana Steud, induced tumor cells apoptosis and decreased the production of ATP and lactic acid in mouse melanoma B16F10 cells. Furthermore, we found that JB downregulated the mRNA expression of glucose transporter genes (Glut1, Glut3 and Glut4) and glycolysis-related kinase genes (Hk2 and Ldha) in B16F10 cells. Moreover, treatment with JB upregulated the mRNA expression of pro-apoptosis genes (Bax), downregulated the mRNA expression of anti-apoptosis genes (Bcl-2, Caspase-3 and Caspase-9), decreased the potential of mitochondrial membrane and increased reactive oxygen species (ROS) levels in B16F10 cells. Finally, intragastric administration of JB suppressed tumor growth and induced tumor apoptosis in mouse xenograft model of murine melanoma B16F10 cells. Taken together, these results suggest that JB could induce apoptosis through the mitochondrial pathway and inhibit tumor growth. The inhibition of glycolysis could play a crucial role in the induction of apoptosis in JB-treated B16F10 cells.
Sex differences in colonization of gut microbiota from a man with short-term vegetarian and inulin-supplemented diet in germ-free mice
Authors: Wang Jing-jing , Wang Jing , Pang Xiao-yan , Zhao Li-ping , Tian Ling , Wang Xing-peng
Published: October 2016

Gnotobiotic mouse model is generally used to evaluate the efficacy of gut microbiota. Sex differences of gut microbiota are acknowledged, yet the effect of recipient’s gender on the bacterial colonization remains unclear. Here we inoculated male and female germ-free C57BL/6J mice with fecal bacteria from a man with short-term vegetarian and inulin-supplemented diet. We sequenced bacterial 16S rRNA genes V3-V4 region from donor’s feces and recipient’s colonic content. Shannon diversity index showed female recipients have higher bacteria diversity than males. Weighted UniFrac principal coordinates analysis revealed the overall structures of male recipient’s gut microbiota were significantly separated from those of females, and closer to the donor. Redundancy analysis identified 46 operational taxonomic units (OTUs) differed between the sexes. The relative abundance of 13 OTUs were higher in males, such as Parabacteroides distasonis and Blautia faecis, while 33 OTUs were overrepresented in females, including Clostridium groups and Escherichia fergusonii/Shigella sonnei. Moreover, the interactions of these differential OTUs were sexually distinct. These findings demonstrated that the intestine of male and female mice preferred to accommodate microbiota differently. Therefore, it is necessary to designate the gender of gnotobiotic mice for complete evaluation of modulatory effects of gut microbiota from human feces upon diseases.
Pollen/TLR4 Innate Immunity Signaling Initiates IL-33/ST2/Th2 Pathways in Allergic Inflammation
Authors: Li Jin , Zhang Lili , Chen Xin , Chen Ding , Hua Xia , Bian Fang , Deng Ruzhi , Lu Fan , Li Zhijie , Pflugfelder Stephen C. , Li De-Quan
Published: October 2016

Innate immunity has been extended to respond environmental pathogen other than microbial components. Here we explore a novel pollen/TLR4 innate immunity in allergic inflammation. In experimental allergic conjunctivitis induced by short ragweed (SRW) pollen, typical allergic signs, stimulated IL-33/ST2 signaling and overproduced Th2 cytokine were observed in ocular surface, cervical lymph nodes and isolated CD4+ T cells of BALB/c mice. These clinical, cellular and molecular changes were significantly reduced/eliminated in TLR4 deficient (Tlr4-d) or MyD88 knockout (MyD88−/−) mice. Aqueous SRW extract (SRWe) directly stimulated IL-33 mRNA and protein expression by corneal epithelium and conjunctiva in wild type, but not in Tlr4-d or MyD88−/− mice with topical challenge. Furthermore, SRWe-stimulated IL-33 production was blocked by TLR4 antibody and NF-kB inhibitor in mouse and human corneal epithelial cells. These findings for the first time uncovered a novel mechanism by which SRW pollen initiates TLR4-dependent IL-33/ST2 signaling that triggers Th2-dominant allergic inflammation.
Rawcopy: Improved copy number analysis with Affymetrix arrays
Authors: Mayrhofer Markus , Viklund Björn , Isaksson Anders
Published: October 2016

Microarray data is subject to noise and systematic variation that negatively affects the resolution of copy number analysis. We describe Rawcopy, an R package for processing of Affymetrix CytoScan HD, CytoScan 750k and SNP 6.0 microarray raw intensities (CEL files). Noise characteristics of a large number of reference samples are used to estimate log ratio and B-allele frequency for total and allele-specific copy number analysis. Rawcopy achieves better signal-to-noise ratio and higher proportion of validated alterations than commonly used free and proprietary alternatives. In addition, Rawcopy visualizes each microarray sample for assessment of technical quality, patient identity and genome-wide absolute copy number states. Software and instructions are available at http://rawcopy.org.
Energy-filtered Electron Transport Structures for Low-power Low-noise 2-D Electronics
Authors: Pan Xuan , Qiu Wanzhi , Skafidas Efstratios
Published: October 2016

In addition to cryogenic techniques, energy filtering has the potential to achieve high-performance low-noise 2-D electronic systems. Assemblies based on graphene quantum dots (GQDs) have been demonstrated to exhibit interesting transport properties, including resonant tunnelling. In this paper, we investigate GQDs based structures with the goal of producing energy filters for next generation lower-power lower-noise 2-D electronic systems. We evaluate the electron transport properties of the proposed GQD device structures to demonstrate electron energy filtering and the ability to control the position and magnitude of the energy passband by appropriate device dimensioning. We also show that the signal-to-thermal noise ratio performance of the proposed nanoscale device can be modified according to device geometry. The tunability of two-dimensional GQD structures indicates a promising route for the design of electron energy filters to produce low-power and low-noise electronics.
Antileukemic Scalarane Sesterterpenoids and Meroditerpenoid from Carteriospongia (Phyllospongia) sp., Induce Apoptosis via Dual Inhibitory Effects on Topoisomerase II and Hsp90
Authors: Lai Kuei-Hung , Liu Yi-Chang , Su Jui-Hsin , El-Shazly Mohamed , Wu Chih-Fung , Du Ying-Chi , Hsu Yu-Ming , Yang Juan-Cheng , Weng Ming-Kai , Chou Chia-Hua , Chen Guan-Yu , Chen Yu-Cheng , Lu Mei-Chin
Published: October 2016

Two new scalarane sesterterpenoids, 12β-(3′β-hydroxybutanoyloxy)-20,24-dimethyl-24-oxo-scalara-16-en-25-al (1) and 12β-(3′β-hydroxypentanoyloxy)-20,24-dimethyl-24-oxo-scalara-16-en-25-al (2), along with one known tetraprenyltoluquinol-related metabolite (3), were isolated from the sponge Carteriospongia sp. In leukemia Molt 4 cells, 1 at 0.0625 μg/mL (125 nM) triggered mitochondrial membrane potential (MMP) disruption and apoptosis showing more potent effect than 2 and 3. The isolates inhibited topoisomerase IIα expression. The apoptotic-inducing effect of 3 was supported by the in vivo experiment through suppressing the volume of xenograft tumor growth (47.58%) compared with the control. Compound 1 apoptotic mechanism of action in Molt 4 cells was further elucidated through inducing ROS generation, calcium release and ER stress. Using the molecular docking analysis, 1 exhibited more binding affinity to N-terminal ATP-binding pocket of Hsp90 protein than 17-AAG, a standard Hsp90 inhibitor. The expression of Hsp90 client proteins, Akt, p70S6k, NFκB, Raf-1, p-GSK3β, and XIAP, MDM 2 and Rb2, and CDK4 and Cyclin D3, HIF 1 and HSF1 were suppressed by the use of 1. However, the expression of Hsp70, acetylated tubulin, and activated caspase 3 were induced after 1 treatment. Our results suggested that the proapoptotic effect of the isolates is mediated through the inhibition of Hsp90 and topoisomerase activities.
Metabolomics reveals the protective of Dihydromyricetin on glucose homeostasis by enhancing insulin sensitivity
Authors: Le Liang , Jiang Baoping , Wan Wenting , Zhai Wei , Xu Lijia , Hu Keping , Xiao Peigen
Published: October 2016

Dihydromyricetin (DMY), an important flavanone found in Ampelopsis grossedentata, possesses antioxidative properties that ameliorate skeletal muscle insulin sensitivity and exert a hepatoprotective effect. However, little is known about the effects of DMY in the context of high-fat diet (HFD)-induced hepatic insulin resistance. Male Sprague-Dawley(SD) rats were fed a HFD(60% fat) supplemented with DMY for 8 weeks. The administration of DMY to the rats with HFD-induced insulin resistance reduces hyperglycemia, plasma levels of insulin, and steatosis in the liver. Furthermore, DMY treatment modulated 24 metabolic pathways, including glucose metabolism, the TCA cycle. DMY significantly enhanced glucose uptake and improved the translocation of glucose transporter 1. The specificity of DMY promoted the phosphorylation of AMP-activated protein kinase (AMPK). In addition, the exposure of HepG2 cells to high glucose concentrations impaired the insulin-stimulated phosphorylation of Akt2 Ser474 and insulin receptor substrate-1 (IRS-1) Ser612, increased GSK-3β phosphorylation, and upregulated G6Pase and PEPCK expression. Collectively, DMY improved glucose-related metabolism while reducing lipid levels in the HFD-fed rats. These data suggest that DMY might be a useful drug for use in type 2 diabetes insulin resistance therapy and for the treatment of hepatic steatosis.
Big Area Additive Manufacturing of High Performance Bonded NdFeB Magnets
Authors: Li Ling , Tirado Angelica , Nlebedim I. C. , Rios Orlando , Post Brian , Kunc Vlastimil , Lowden R. R. , Lara-Curzio Edgar , Fredette Robert , Ormerod John , Lograsso Thomas A. , Paranthaman M. Parans
Published: October 2016

Additive manufacturing allows for the production of complex parts with minimum material waste, offering an effective technique for fabricating permanent magnets which frequently involve critical rare earth elements. In this report, we demonstrate a novel method - Big Area Additive Manufacturing (BAAM) - to fabricate isotropic near-net-shape NdFeB bonded magnets with magnetic and mechanical properties comparable or better than those of traditional injection molded magnets. The starting polymer magnet composite pellets consist of 65 vol% isotropic NdFeB powder and 35 vol% polyamide (Nylon-12). The density of the final BAAM magnet product reached 4.8 g/cm3, and the room temperature magnetic properties are: intrinsic coercivity Hci = 688.4 kA/m, remanence Br = 0.51 T, and energy product (BH)max = 43.49 kJ/m3 (5.47 MGOe). In addition, tensile tests performed on four dog-bone shaped specimens yielded an average ultimate tensile strength of 6.60 MPa and an average failure strain of 4.18%. Scanning electron microscopy images of the fracture surfaces indicate that the failure is primarily related to the debonding of the magnetic particles from the polymer binder. The present method significantly simplifies manufacturing of near-net-shape bonded magnets, enables efficient use of rare earth elements thus contributing towards enriching the supply of critical materials.
Interferon-alpha therapy for refractory kaposiform hemangioendothelioma: a single-center experience
Authors: Wu Hai Wei , Wang Xuan , Zhang Ling , Zhao Hai Guang , Wang Yan An , Su Li Xin , Fan Xin Dong , Zheng Jia Wei
Published: October 2016

Kaposiform hemangioendothelioma (KHE) is a relatively rare vascular tumor with an aggressive and infiltrating nature. Previous studies have revealed an exclusive relationship between KHE and Kasabach-Merritt Phenomenon (KMP), which is associated with high morbidity and mortality. No universally accepted treatment modality exists for refractory KHE with or without KMP. The aim of this study was to evaluate the safety and efficacy of interferon-alpha (IFN-α) therapy for treatment of refractory KHE. Twelve consecutive patients with KHE were treated with subcutaneous injections of IFN-α after other treatments had failed. Eleven patients exhibited a reduction in tumor size of more than 50%, and the platelet count for all five patients with KMP returned to normal level after IFN-α therapy. The duration of IFN-α treatment ranged from 3 months to 9 months (mean: 6.3 months). The response time for IFN-α treatment ranged from 10 days to 5 weeks (mean: 3.6 weeks). Additionally, no severe complications, such as neurological damage or spastic diplegia, were observed in these patients. In conclusion, our study suggested that IFN-α therapy is effective and safe for refractory KHE, and IFN-α may be used as an alternative after other treatments have failed.
The osteogenic potential of human bone callus
Authors: Han Weiqi , He Wei , Yang Wanlei , Li Jianlei , Yang Zhifan , Lu Xuanyuan , Qin An , Qian Yu
Published: October 2016

Bone callus, generated during fracture healing, is commonly discarded during surgical procedures. The aim of this study was to investigate the osteogenic potential of bone callus and its possible use as autograft material for patients needing bone grafts. Histology, immunohistochemistry, micro-computed tomography, and biomechanics were performed to examine osteogenic cells, osteoinductive factors, and the osteoconductive structure of bone callus. Alkaline phosphatase-positive osteoblasts, osteoinductive factors (including BMP2, FGF2, TGFB1, and IGF1), and a porous structure were found in bone callus. Early-stage callus (within 3 months after fracture) presented significantly improved osteogenic properties compared to medium- (3–9 months) and late-stage (longer than 9 months) callus. The results revealed that bone callus induced new bone formation in a nude mouse model. Early-stage callus showed better performance to medium- and late-stage callus in the induction of new bone formation at both 8 and 12 weeks. These findings indicated that bone callus, especially early-stage callus, possesses osteogenic potential and can potentially serve as an alternative source of material for bone grafts.
An approach for extraction, characterization and quantitation of microplastic in natural marine snow using Raman microscopy
Authors: Zhao Shiye , Danley Meghan , Ward J. Evan , Li Daoji , Mincer Tracy J.
Published: October 2016

Marine snow is a predominant form of sinking particulate carbon in the marine water column and represents a mechanism for transporting microplastics to the sea floor.
A bifunctional solid oxide electrolysis cell for simultaneous CO2 utilization and synthesis gas production
Authors: Sun Yi-Fei , Wu Yi-Yang , Zhang Ya-Qian , Li Jian-Hui , Luo Yu , Shi Yi-Xiang , Hua Bin , Luo Jing-Li
Published: October 2016

Herein, we report a pioneering solid oxide cell which consumes CO2 to produce CO at the cathode side and simultaneously synthesizes valuable syngas at the anode side via a one-step green process.
Chiral nanostructure in polymers under different deposition conditions observed using atomic force microscopy of monolayers: poly(phenylacetylene)s as a case study
Authors: Freire F. , Quiñoá E. , Riguera R.
Published: October 2016

Techniques used for the study of the secondary structure of polymers by means of atomic-force microscopy are evaluated.
O2 selective membranes based on a dextrin-nanosponge (NS) in a PVDF-HFP polymer matrix for Li–air cells
Authors: Amici J. , Alidoost M. , Francia C. , Bodoardo S. , Martinez Crespiera S. , Amantia D. , Biasizzo M. , Caldera F. , Trotta F.
Published: October 2016

A novel oxygen selective highly hydrophobic membrane is prepared by non-solvent induced phase separation in which a dextrin-based nanosponge is incorporated into a PVDF-HFP matrix.
Protic organic ionic plastic crystals based on a difunctional cation and the triflate anion: a new solid-state proton conductor
Authors: Rao Jun , Vijayaraghavan R. , Chen Fangfang , Zhu Haijin , Howlett Patrick C. , MacFarlane Douglas R. , Forsyth Maria
Published: October 2016

A new family of ammonium based organic ionic plastic crystals exhibits exciting solid-state proton conductivity.
Self-assembly and photocatalytic H2 evolution activity of two unprecedented polytantalotungstates based on the largest {Ta18} and {Ta18Yb2} clusters
Authors: Huang Peng , Qin Chao , Zhou Yu , Hong Yu-Mei , Wang Xin-Long , Su Zhong-Min
Published: October 2016

Two unprecedented polytantalotungstates, 1 and 2 based on the largest {Ta18} and {Ta18Yb2} clusters, respectively, were synthesized. 1 and 2 exhibit significant UV photocatalytic water splitting activity.
Two-photon fluorescence imaging of sialylated glycans in vivo based on a sialic acid imprinted conjugated polymer nanoprobe
Authors: Zhang Wei , Kang Junqing , Li Ping , Liu Lu , Wang Hui , Tang Bo
Published: October 2016

We have designed and synthesized an SA-imprinted conjugated polymer nanoprobe with two-photon fluorescence properties, which exhibits specific recognition ability to the target SA and has been used for monitoring sialylated glycan levels selectivelyin vivo.
An improved model of homogeneous nucleation for high supersaturation conditions: aluminum vapor
Authors: Savel'ev A. M. , Starik A. M.
Published: October 2016

A novel model of stationary nucleation, treating the thermodynamic functions of small clusters, has been built.
Modelling temperature-dependent properties of polymorphic organic molecular crystals
Authors: Nyman Jonas , Day Graeme M.
Published: October 2016

We examine the importance of thermal expansion on relative stabilities and properties of crystalline polymorphs.
Raman study of 2D anatase TiO2 nanosheets
Authors: Zhang Yang , Wu Wei , Zhang Ke , Liu Caihong , Yu Aifang , Peng Mingzeng , Zhai Junyi
Published: October 2016

Studies of the thickness-dependent Raman shift in 2D anatase TiO2 nanosheets provide a convenient and reliable method to characterize their thickness.
Energy frameworks and a topological analysis of the supramolecular features in in situ cryocrystallized liquids: tuning the weak interaction landscape via fluorination
Authors: Dey Dhananjay , Bhandary Subhrajyoti , Thomas Sajesh P. , Spackman Mark A. , Chopra Deepak
Published: October 2016

The weak interactions assist in tuning the growth of π⋯π stacking with fluorine substitution inin situcryocrystallized liquids.
Controlled synthesis of carbon-supported Co catalysts from single-sites to nanoparticles: characterization of the structural transformation and investigation of their oxidation catalysis
Authors: Nakatsuka Kazuki , Yoshii Takeharu , Kuwahara Yasutaka , Mori Kohsuke , Yamashita Hiromi
Published: October 2016

Structural transformation of Co species supported on activated carbon during heat treatment and the structure–activity relationship of the resulting species in the oxidation of ethylbenzene were investigated.
Incorporating conjugated carbonyl compounds into carbon nanomaterials as electrode materials for electrochemical energy storage
Authors: Yang Guanhui , Zhang Yu , Huang Yanshan , Shakir Muhammad Imran , Xu Yuxi
Published: October 2016

This review provided an overview of recent progress on composites of conjugated carbonyl compounds and carbon nanomaterials for energy storage.
Synthesis and characterization of metal–rich phosphonium polyelectrolytes and their use as precursors to nanomaterials
Authors: Rabiee Kenaree Amir , Gilroy Joe B.
Published: October 2016

A unique family of polyelectrolytes with four different stoichiometric Fe/Ru ratios were prepared and characterized. Pyrolysis in a reducing atmosphere led to crystalline, mixed phase nanomaterials containing iron, ruthenium, and phosphorus with compositions influenced by the structure of the parent polyelectrolytes.
Photochemical water splitting mediated by a C1 shuttle
Authors: Alderman N. P. , Sommers J. M. , Viasus C. J. , Wang C. H. T. , Peneau V. , Gambarotta S. , Vidjayacoumar B. , Al-Bahily K. A.
Published: October 2016

Photochemical water splitting was achieved in a two-stage system with the aid of a formaldehyde/formate redox couple.
A lysosome targetable luminescent bioprobe based on a europium β-diketonate complex for cellular imaging applications
Authors: George T. M. , Krishna Mahesh S. , Reddy M. L. P.
Published: October 2016

A unique bright luminescent europium coordination compound with excellent biocompatibility has been developed that serves as a selective bioprobe for particular organelles within the cells.
Review: imaging technologies for flow cytometry
Authors: Han Yuanyuan , Gu Yi , Zhang Alex Ce , Lo Yu-Hwa
Published: October 2016

Imaging flow cytometry combines the single-cell imaging capabilities of microscopy with the high-throughput capabilities of conventional flow cytometry. This article describes recent imaging flow cytometry technologies and their challenges.
Designing different morphologies of NiFe2O4 for tuning of structural, optical and magnetic properties for catalytic advancements
Authors: Dhiman Manisha , Goyal Ankita , Kumar Vinod , Singhal Sonal
Published: October 2016

Variations adopted in synthetic methodology have incorporated quite interesting and beneficial modifications in structural, magnetic, morphological, surface and catalytic properties.
Gate-controlled conductance enhancement from quantum Hall channels along graphene p–n junctions
Authors: Tóvári Endre , Makk Péter , Liu Ming-Hao , Rickhaus Peter , Kovács-Krausz Zoltán , Richter Klaus , Schönenberger Christian , Csonka Szabolcs
Published: October 2016

The conductance enhancement of QH states propagating far from disordered edges is directly observed. Separate biasing of channels, and gate-controlled transmission to contacts is demonstrated.
Synthesis of degradable poly(ε-caprolactone)-based graft copolymers via a “grafting-from” approach
Authors: Bexis Panagiotis , Thomas Anthony W. , Bell Craig A. , Dove Andrew P.
Published: October 2016

The controlled ring-opening polymerisation (ROP) of α-bromo-ε-caprolactone (αBrCL), a derivative of ε-caprolactone (εCL), and its copolymerisation with εCL is reported.
Physically cross-linked pH-responsive chitosan-based hydrogels with enhanced mechanical performance for controlled drug delivery
Authors: Che YuJu , Li Dongping , Liu Yulong , Ma Qinglin , Tan Yebang , Yue Qinyan , Meng Fanjun
Published: October 2016

A novel physically cross-linked pH-responsive hydrogel with enhanced mechanical performance was prepared from chitosan, acrylic acid and (2-dimethylamino) ethyl methacrylatevia in situfree radical polymerization for controlled drug delivery.
Synthesis, characterization, in vitro cytotoxicity, in silico ADMET analysis and interaction studies of 5-dithiocarbamato-1,3,4-thiadiazole-2-thiol and its zinc(ii) complex with human serum albumin: combined spectroscopy and molecular docking investigations
Authors: Shiri Fereshteh , Shahraki Somaye , Baneshi Sadegh , Nejati-Yazdinejad Massoud , Majd Mostafa Heidari
Published: October 2016

The binding site of new complex Zn(ii) of 5-dithiocarbamato-1,3,4-thiadiazole-2-thiol and HAS.
Electric field-assisted ultrafast synthesis of nanopowders: a novel and cost-efficient approach
Authors: Jesus Lílian M. , Silva Ronaldo S. , Raj Rishi , M'Peko Jean-Claude
Published: October 2016

Ultrafast synthesis of CaCu3Ti4O12 nanopowder by the action of an electric field on the corresponding chemically-prepared amorphous precursor.
Use of dicyanamide ionic liquids for extraction of metal ions
Authors: Boudesocque S. , Mohamadou A. , Dupont L. , Martinez A. , Déchamps I.
Published: October 2016

A correlation between the extraction capacity of tetraalkylammonium dicyanamide ILs and the nature of the anion of the metal salt was investigated.
Remote stereocontrolled asymmetric 1,6-addition/1,4-addition cascade reactions between cyclic dienones and 2-indolinethiones
Authors: Sun Xiaohua , Fei Jie , Zou Chuncheng , Lu Min , Ye Jinxing
Published: October 2016

Enantioselective 1,6-addition/1,4-addition cascade reactions between cyclic dienones and 2-indolnethiones have been realized, affording chiral spiro[thiopyranoindole-cyclohexanone] scaffolds facilely and efficiently.
Effect of sulfur substitution on the thermoelectric properties of (SnSe)1.16NbSe2: charge transfer in a misfit layered structure
Authors: Jood Priyanka , Ohta Michihiro
Published: October 2016

First time investigation of the thermoelectric properties of misfit layered (SnSe)1.16NbSe2 and new insights into the charge transfer tuning in misfit systems.
Novel synthesis of pure VO2@SiO2 core@shell nanoparticles to improve the optical and anti-oxidant properties of a VO2 film
Authors: Wang Min , Tian Jianjian , Zhang Heng , Shi Xiang , Chen Zhang , Wang Yu , Ji Aiyan , Gao Yanfeng
Published: October 2016

A novel moderately surfactant-free strategy for the synthesis of pure VO2@SiO2 core@shell nanoparticles to improve the optical and anti-oxidant properties of VO2 particles, which involves potential interface chemistry.
Revival, enhancement and tuning of fluorescence from Coumarin 6: combination of host–guest chemistry, viscosity and collisional quenching
Authors: Banerjee Rajashree , Mondal Somen , Purkayastha Pradipta
Published: October 2016

The self-quenched fluorescence of Coumarin 6 can be revived by host–guest chemistry and further increased by about 40% on increasing the solvent viscosity and hence restricting the motion of the molecules.
Thermally reversible solidification of novel ionic liquid [im]HSO4by self-nucleated rapid crystallization: investigations of ionic conductivity, thermal properties, and catalytic activity
Authors: Bielejewski Michał , Ghorbani Mahdi , Zolfigol Mohammad Ali , Tritt-Goc Jadwiga , Noura Soheila , Narimani Mahdi , Oftadeh Mohsen
Published: October 2016

A new, multifunctional [im]HSO4ionic liquid: a thermally reversible solid-state electrolyte and an efficient catalyst for acid-catalyzed chemical processes.
Superparamagnetic yolk–shell porous nanospheres of iron oxide@magnesium silicate: synthesis and application in high-performance anticancer drug delivery
Authors: Sun Tuan-Wei , Zhu Ying-Jie , Chen Feng , Qi Chao , Lu Bing-Qiang , Wu Jin , Zhou Ding , Zhang Chang-Qing
Published: October 2016

The as-prepared yolk–shell porous nanospheres of SPIO@MS exhibit a high drug loading capacity, and a sustained and pH-responsive drug release behaviour.
The mechanical properties and thermal stability of ultrathin germanium nanowires
Authors: Yang Po-Yu , Ju Shin-Pon , Lai Zhu-Min , Hsieh Jin-Yuan , Lin Jenn-Sen
Published: October 2016

The mechanical properties of ultrathin germanium nanowires are investigated: the mechanical properties of the nanowires are severely reduced when temperature increases.
Dual-stimuli-responsive glycopolymer bearing a reductive and photo-cleavable unit at block junction
Authors: Fang Jia-You , Lin Yin-Ku , Wang Shiu-Wei , Yu Yung-Ching , Lee Ren-Shen
Published: October 2016

Dual-stimuli-cleavable glycopolymers bearing a reductive and photo-cleavable unit at block junction were synthesized and characterization.
Facile synthesis of quinoxaline annulated perfluoroalkylated benzoazepine derivatives
Authors: Liu Gang , Sun Xuechun , Chen Ling , Wu Yueci , Han Jing , Chen Jie , Deng Hongmei , Shao Min , Zhang Hui , Cao Weiguo
Published: October 2016

Perfluoroalkylated benzoazepinoquinoxalines 3 were synthesized by a consecutive intermolecular Michael addition and intramolecular cyclization from 3-(2-aminophenyl)quinoxalin-2(1H)-ones 1 and methyl perfluoroalk-2-ynoates 2 in good yields.
A novel pyrazole based single molecular probe for multi-analyte (Zn2+ and Mg2+) detection in human gastric adenocarcinoma cells
Authors: Dhara Anamika , Guchhait Nikhil , Mukherjee Indrani , Mukherjee Abhishek , Chandra Bhattacharya Subhash
Published: October 2016

A newly designed fluorescent sensor 5-methyl-1H-pyrazole-3-carboxylic acid (6-methoxy-naphthalen-2-ylmethylene)-hydrazide (PYN) shows excellent selectivity and sensitivity with a fluorescence enhancement towards Zn2+ and Mg2+ ions in aqueous acetonitrile solution.
Adsorption of ionic liquid from aqueous solutions using functional corncob-cellulose nanocrystals
Authors: Yu Fang , Zhou Yanmei , Qiao Han , Sun Li , Li Li , Feng Caixia , Li Yonghong
Published: October 2016

We report novel adsorbents, based on corncob-cellulose nanocrystals, for the efficient absorption of ionic liquid (1-butyl-3-methylimidazolium chloride, [Bmim]Cl) from aqueous solutions.
Unraveling the physical chemistry and the mixed binding modes of complex DNA ligands by single molecule stretching experiments
Authors: Bernal W. F. P. , Silva E. F. , Rocha M. S.
Published: October 2016

In this work we present a complete methodology to unravel the physical chemistry and the mixed binding modes of complex DNA ligands.
Construction of novel pH-sensitive hybrid micelles for enhanced extracellular stability and rapid intracellular drug release
Authors: Yin Shaoping , Chang Liang , Li Tie , Wang Guangji , Gu Xiaochen , Li Juan
Published: October 2016

Novel pH-sensitive hybrid micelles with high entrapment efficiency were constructed to realize rapid intracellular drug release without premature release.
A multi-addressable diarylethene for the selective detection of Al3+ and the construction of a logic circuit
Authors: Cui Shiqiang , Tang Yongjuan , Lu Ruimin , Pu Shouzhi
Published: October 2016

A multi-addressable diarylethene was designed and synthesized, which not only acted as a fluorescent sensor for Al3+ with high selectivity, but was also used to construct a combinational logic circuit.
Acidic ionic liquid modified silica gel for adsorption and separation of bovine serum albumin (BSA)
Authors: Song Hang , Yang Chang , Yohannes Alula , Yao Shun
Published: October 2016

In this work, silica gel (SiO2) was modified with an acidic ionic liquid (Im+·HSO4−) and the product was characterized using infrared spectroscopy, thermogravimetric analysis and elemental measurement.
Size effect of SO2 receptors on the energy efficiency of Na–SO2 batteries: gallium-based inorganic electrolytes
Authors: Yim Taeeun , Jeong Goojin , Han Young-Kyu , Kim Young-Jun
Published: October 2016

Na–SO2 batteries have garnered significant attention as alternative energy conversion/storage systems, however, their low energy efficiency, which corresponds to large polarization, is a crucial restriction in achieving high performance of the cell.
Sorption behaviour of Pu4+and PuO22+on amido amine-functionalized carbon nanotubes: experimental and computational study
Authors: Kumar Parveen , Sengupta Arijit , Singha Deb Ashish Kumar , Dasgupta Kinshuk , Ali Sk. Musharaf
Published: October 2016

Amido amine-functionalized multi-walled carbon nanotubes (MWCNT-AA) were used for efficient and selective solid phase separation of plutonium(iv) and plutonium(vi).
Facile rhodamine-based colorimetric sensors for sequential detections of Cu(ii) ions and pyrophosphate (P2O74−) anions
Authors: Arumugaperumal Reguram , Srinivasadesikan Venkatesan , Lin Ming-Chang , Shellaiah Muthaiah , Shukla Tarun , Lin Hong-Cheu
Published: October 2016

Two rhodamine hydrazine derivatives Rh1 and Rh2 with catechol and ether functionalities have been synthesized and utilized towards sequential colorimetric detections of Cu(ii) and pyrophosphate (PPi) ions in a semi-aqueous medium.
Significantly enhanced energy storage density of sandwich-structured (Na0.5Bi0.5)0.93Ba0.07TiO3/P(VDF–HFP) composites induced by PVP-modified two-dimensional platelets
Authors: Jiang Chao , Zhang Dou , Zhou Kechao , Zhou Xuefan , Luo Hang , Abrahams Isaac
Published: October 2016

Layered composites involving NBBT platelets in a polymer matrix show excellent energy storage properties.
Controllable orientation-dependent crystal growth of high-index faceted dendritic NiC0.2nanosheets as high-performance bifunctional electrocatalysts for overall water splitting
Authors: Yang Haidong , Luo Sha , Li Xinzhe , Li Shuwen , Jin Jun , Ma Jiantai
Published: October 2016

The controllable orientation-dependent crystal growth of high-index faceted d-NiC0.2NS/Ni/CF catalysts with remarkable catalytic performance for both the HER and OER was successfully achieved by a mild electrodeposition approach.
Noble metal-free ultrathin MoS2 nanosheet-decorated CdS nanorods as an efficient photocatalyst for spectacular hydrogen evolution under solar light irradiation
Authors: Kumar D. Praveen , Hong Sangyeob , Reddy D. Amaranatha , Kim Tae Kyu
Published: October 2016

This work demonstrates a novel strategy for high H2 production rate from noble metal-free ultrathin MoS2 nanosheets-decorated CdS nanorods under natural solar light irradiation.
Highly responsive UV-photodetectors based on single electrospun TiO2 nanofibres
Authors: Molina-Mendoza Aday J. , Moya Alicia , Frisenda Riccardo , Svatek Simon A. , Gant Patricia , Gonzalez-Abad Sergio , Antolin Elisa , Agraït Nicolás , Rubio-Bollinger Gabino , Perez de Lara David , Vilatela Juan J. , Castellanos-Gomez Andres
Published: October 2016

Electrospun TiO2 single-nanofibres are employed as photodetectors with state-of-the-art performance: high sensitivity in the UV (responsivity of 90 A W−1 for 375 nm wavelength), response time of ∼5 s and light polarisation sensitivity.
Plasma-assisted atomic layer deposition and post-annealing enhancement of low resistivity and oxygen-free nickel nano-films using nickelocene and ammonia precursors
Authors: Wang Yong-Ping , Ding Zi-Jun , Liu Qi-Xuan , Liu Wen-Jun , Ding Shi-Jin , Zhang David Wei
Published: October 2016

Oxygen-free and low resistivity nickel (Ni) thin films are successfully prepared by plasma-assisted atomic layer deposition using nickelocene (NiCp2) as a metal precursor and ammonia (NH3) as a reactant.
Homoleptic zirconium amidates: single source precursors for the aerosol-assisted chemical vapour deposition of ZrO2
Authors: Catherall Amanda L. , Hill Michael S. , Johnson Andrew L. , Kociok-Köhn Gabriele , Mahon Mary F.
Published: October 2016

We report the development of a true single source precursor for the growth of zirconia thin films by aerosol-assisted chemical vapour deposition using an original family of zirconium(iv) amidate derivatives.
Titanium mesh supported TiO2 nanowire arrays/Nb-doped TiO2 nanoparticles for fully flexible dye-sensitized solar cells with improved photovoltaic properties
Authors: Liu Wenwu , Wang Hui-gang , Wang Xiaofei , Zhang Mei , Guo Min
Published: October 2016

TiO2 nanowire arrays/2.4 mol% Nb-doped TiO2 nanoparticles composites were synthesized on Ti-mesh substrates using a hydrothermal approach for fully flexible dye-sensitized solar cells that exhibited good 7.20% conversion efficiency.
Crystal structure, tunable emission and applications of Ca1−xAl1−xSi1+xN3−xOx:RE (x = 0–0.22, RE = Ce3+, Eu2+) solid solution phosphors for white light-emitting diodes
Authors: Li Shuxing , Wang Le , Zhu Qiangqiang , Tang Daiming , Liu Xuejian , Cheng Guofeng , Lu Lu , Takeda Takashi , Hirosaki Naoto , Huang Zhengren , Xie Rong-Jun
Published: October 2016

The designed Ca1−xAl1−xSi1+xN3−xOx:Eu2+/Ce3+red or yellow phosphors by structure and bandgap engineering afford wLEDs with high color rendition and luminous efficacy.
Prediction of the effect of formulation on the toxicity of chemicals
Authors: Mistry Pritesh , Neagu Daniel , Sanchez-Ruiz Antonio , Trundle Paul R. , Vessey Jonathan D. , Gosling John Paul
Published: October 2016

Two approaches for the prediction of which of two vehicles will result in lower toxicity for anticancer agents are presented.
Digital LDO with 1‐bit ΔΣ modulation for low‐voltage clock generation systems
Authors: Song Haixin , Rhee Woogeun , Shim Inbo , Wang Zhihua
Published: October 2016

A coarse‐fine dual‐loop digital low dropout regulator (DLDO) having a binary weighed transistor array in the coarse loop and a 1‐bit ΔΣ modulator in the fine loop is proposed. Compared with the conventional DLDO, the proposed architecture significantly reduces hardware complexity and alleviates matching requirement, enabling a robust DLDO design for low‐voltage phase‐locked loops. The proposed DLDO designed in 65 nm CMOS generates a noise‐shaped output voltage whose peak value is <1 mV with the load current ranging from 100 μA to 6 mA.
Fast and efficient user pairing and power allocation algorithm for non‐orthogonal multiple access in cellular networks
Authors: He Jianhua , Tang Zuoyin , Che Zhongzhi
Published: October 2016

Non‐orthogonal multiple access (NOMA) is emerging as a promising multiple access technology for the fifth generation cellular networks to address the fast growing mobile data traffic. It applies superposition coding in transmitters, allowing simultaneous allocation of the same frequency resource to multiple intra‐cell users. Successive interference cancellation is used at the receivers to cancel intra‐cell interference. User pairing and power allocation (UPPA) is a key design aspect of NOMA. Existing UPPA algorithms are mainly based on exhaustive search method with extensive computation complexity, which can severely affect the NOMA performance. A fast proportional fairness (PF) scheduling based UPPA algorithm is proposed to address the problem. The novel idea is to form user pairs around the users with the highest PF metrics with pre‐configured fixed power allocation. System‐level simulation results show that the proposed algorithm is significantly faster (seven times faster for the scenario with 20 users) with a negligible throughput loss than the existing exhaustive search algorithm.
Hybrid exploration state for the simplified finite control set‐model predictive control with a deadbeat solution for reducing the current ripple in permanent magnet synchronous motor
Authors: Abbaszadeh Alireza , Arab Khaburi Davood , Kennel Ralph , Rodríguez José
Published: October 2016

This research tends to provide a novel exploration state for finite control set‐model predictive control. The aim of this study is to reduce the line current ripple at a given average switching frequency. The proposed method with hybrid exploration state divides the space vector plane into two regions. Each conventional exploration state is applied to a region, which would result in a lower root mean square current ripple. The above‐mentioned procedure is based on the calculation of the stator flux ripple in the stationary reference frame during the sampling time. Consequently, a simple expression based on the magnitude and the phase angle of the reference voltage vector will be obtained, which can be employed as a measure for the current ripple. The superior performance of the proposed method over the conventional exploration state methods is verified by the theoretical results and the experimental tests.
Comparison between traditional single‐phase auto reclosing and adaptive technique based on harmonic content measurement
Authors: Dias Ozenir , Tavares Maria Cristina
Published: October 2016

This study presents the results of single‐phase auto reclosing technique tests, comparing the performance of traditional procedure and fast adaptive procedure. The last is based on the measurement of voltage harmonic content on the transmission line faulty phase terminals. The transmission system used was modelled on the real‐time digital simulator with a distance relay and a quality meter to more realistically implement the reclosing techniques. The studied system was based on an actual Brazilian 500 kV transmission system. This study highlights the advantages of using the adaptive technique opposite to the use of traditional manoeuvre.