bluuebunny/crossref_metadata_2025 huggingface dataset:
Visual Recognition Memory of Scenes Is Driven by Categorical, Not Sensory, Visual Representations
Authors: Morales-Torres Ricardo , Wing Erik A. , Deng Lifu , Davis Simon W. , Cabeza Roberto
Published: April 2024

When we perceive a scene, our brain processes various types of visual information simultaneously, ranging from sensory features, such as line orientations and colors, to categorical features, such as objects and their arrangements. Whereas the role of sensory and categorical visual representations in predicting subsequent memory has been studied using isolated objects, their impact on memory for complex scenes remains largely unknown. To address this gap, we conducted an fMRI study in which female and male participants encoded pictures of familiar scenes (e.g., an airport picture) and later recalled them, while rating the vividness of their visual recall. Outside the scanner, participants had to distinguish each seen scene from three similar lures (e.g., three airport pictures). We modeled the sensory and categorical visual features of multiple scenes using both early and late layers of a deep convolutional neural network. Then, we applied representational similarity analysis to determine which brain regions represented stimuli in accordance with the sensory and categorical models. We found that categorical, but not sensory, representations predicted subsequent memory. In line with the previous result, only for the categorical model, the average recognition performance of each scene exhibited a positive correlation with the average visual dissimilarity between the item in question and its respective lures. These results strongly suggest that even in memory tests that ostensibly rely solely on visual cues (such as forced-choice visual recognition with similar distractors), memory decisions for scenes may be primarily influenced by categorical rather than sensory representations.
Optogenetic Inhibition of Rat Anterior Cingulate Cortex Impairs the Ability to Initiate and Stay on Task
Authors: Vázquez Daniela , Maulhardt Sean R. , Stalnaker Thomas A. , Solway Alec , Charpentier Caroline J. , Roesch Matthew R.
Published: April 2024

Our prior research has identified neural correlates of cognitive control in the anterior cingulate cortex (ACC), leading us to hypothesize that the ACC is necessary for increasing attention as rats flexibly learn new contingencies during a complex reward-guided decision-making task. Here, we tested this hypothesis by using optogenetics to transiently inhibit the ACC, while rats of either sex performed the same two-choice task. ACC inhibition had a profound impact on behavior that extended beyond deficits in attention during learning when expected outcomes were uncertain. We found that ACC inactivation slowed and reduced the number of trials rats initiated and impaired both their accuracy and their ability to complete sessions. Furthermore, drift–diffusion model analysis suggested that free-choice performance and evidence accumulation (i.e., reduced drift rates) were degraded during initial learning—leading to weaker associations that were more easily overridden in later trial blocks (i.e., stronger bias). Together, these results suggest that in addition to attention-related functions, the ACC contributes to the ability to initiate trials and generally stay on task.
The Problem of the Reinvention of Practices in I. Stengers’ Thought
Authors:   , Rybačiauskaitė Karolina
Published: April 2024

Praktikų perkūrimo problema I. Stengers mąstyme
Dialog “buddhism – western philosophy” as the reality game: An interview with dr. Jan Westerhoff
Authors: KALANTAROVA Olena
Published: April 2024

No one is surprised anymore by the dialogue between Buddhism and Western science, which develops the foundations of cognitive and contemplative sciences. But there have been requests for reflection on the results achieved, or even for a strategy for analytical research of the Buddhist East, which brings this dialogue to the philosophical level. And this level of discussion is, in fact, the dialogue between Buddhism and Western philosophy, which requires a new discourse that should be built on their common ground. And the first question that arises against this background is how to focus attention on the philosophical aspect of Buddhism, which orientalists usually call “Buddhist philosophy”. Thus, realizing the beginning of the dialogue between Buddhist and Western philosophies, we are faced with the need to take the next, but already conscious step in the direction of this discussion. In order to make this step confident, we need to know where and how to start, and what key subjects we can rely on. Therefore, in an effort to find possible warnings against gross mistakes in such discussions, we sought the help of Western experts in the field of Buddhist studies by reading their works and talking to them. One of the well-known scholars is Professor Jan Westerhoff, who kindly agreed to give me an interview and answer some questions: whether there is a Buddhist philosophy; what are the approaches and stages of its research; what are the peculiarities of using the terms of Western philosophy in these studies; what can be the criterion for the best reading of traditional Buddhist texts; what can such a discussion give to contemporary Western philosophy, etc. This interview was not intended to be a conceptual deepening of either Buddhist or Western philosophy; we only tried to identify key questions that could start a dialog between them in the right direction.
DYNAMIC MODEL OF THE RESONANT CONVERTER FOR INFLUENCE FROM THE SUPPLY SIDE
Authors:   Admiral Makarov National University of Shipbuilding, Heroiv Ukrainy av., 9, Mykolaiv, 54007, Ukraine, Pavlov G.V. , Obrubov A.V. ,   Admiral Makarov National University of Shipbuilding, Heroiv Ukrainy av., 9, Mykolaiv, 54007, Ukraine, Vinnychenko I.L. ,   Admiral Makarov National University of Shipbuilding, Heroiv Ukrainy av., 9, Mykolaiv, 54007, Ukraine
Published: April 2024

In the paper, a discrete dynamic model of a full-bridge resonant converter with a symmetrical operating mode has been obtained, which describes the resonant converter as a transfer link with an supply voltage input side and a load current output side. The dynamic model is based on a linear mathematical model of the resonant converter built according to the superposition principle. The structure of the resonant converter with the processes outline function is given and analyzed. The structure of the discrete dynamic model of the resonant converter of the nth order is presented. It is proved that the transfer function of the discrete dynamic model for the outline function can be determined by the transfer function of the continuous system. The resulting dependencies describing the discrete transfer functions of the resonant converter are used to obtain the discrete dynamic model of the double-circuit transformer resonant converter in a synchronous rectifier. For this, the sequence of actions is defined: definition of the transfer function of the continuous dynamic model; obtaining the system of equations in vector-matrix form describing electromagnetic processes in the converter; definition of the system of discrete equations; definition of the transfer function of the circuit. The obtained theoretical results were verified by means of simulation modeling of the considered double-circuit resonant converter. The proposed dynamic model makes it possible to analyze the influence of instability and low-frequency fluctuations of the supply voltage of the resonant converter on the output values. The presented results can be used in the development and improvement of single- or multi-circuit bridge high-frequency resonant converters as the secondary power sources and converters used in ship demagnetization systems. References 25, figures 8, tables 2.
ANALYSIS OF THE RESULTS OF EXPERIMENTAL RESEARCH ON THE INHOMOGENITY OF THE DIRECT CURRENT NETWORK
Authors:   National Technical University of Ukraine Ihor Sikorsky Kyiv Polytechnic Institute,  Beresteiskyi Ave., 37, Kyiv, 03056, Ukraine, Grebchenko N.V. , Sopel M.F. ,   Private enterprise «ANIGER»,  Harmatna str., 2, Kyiv, 03056, Ukraine, Spodynskyi О.V. ,   Institute of Electrodynamics National Academy of Sciences of Ukraine, Beresteiskyi Ave., 56, Kyiv, 03057, Ukraine
Published: April 2024

The modes of breakage of one line of network sections with parallel lines in electrical distribution networks of power supply to consumers of direct current electric transport have been studied. An analysis of the experimental data was carried out, the results of which indicate the presence of a dependence of the value of the variable component in the rectified current on the distance to the damaged area. Mathematical modeling of the breakage mode of one of the line sections in the network with a serial connection of three sections, each of which has parallel lines, has been carried out. The obtained results of mathematical modeling of the modes of operation of a direct current network with heterogeneity of different sections also indicate the possibility of using the sixth harmonic of the current to determine the occurrence of heterogeneity and the section with this heterogeneity. To reduce the influence of load changes when determining an inhomogeneous section, it is proposed to control the input impedance of the network at a frequency of 300 Hz. It has been established that in these regimes the resistance angle changes the most. A method for determining the occurrence of local damage to a direct current line and the distance to this damage location is proposed, which is based on moni-toring the value of the line current and the input resistance of the line at a frequency of 300 Hz. References 7, Figures 4, Tables 2.
The Therapy and Management of Heart Failure with Preserved Ejection Fraction: New Insights on Treatment
Authors: Balestrieri Giulio , Limonta Raul , Ponti Enrico , Merlo Anna , Sciatti Edoardo , D’Isa Salvatore , Gori Mauro , Casu Gavino , Giannattasio Cristina , Senni Michele , D’Elia Emilia
Published: April 2024

Heart failure with preserved ejection fraction (HFpEF) is a clinical syndrome characterised by the presence of diastolic dysfunction and elevated left ventricular filling pressure, in the setting of a left ventricular ejection fraction of at least 50%. Despite the epidemiological prevalence of HFpEF, a prompt diagnosis is challenging and many uncertainties exist. HFpEF is characterised by different phenotypes driven by various cardiac and non-cardiac comorbidities. This is probably the reason why several HFpEF clinical trials in the past did not reach strong outcomes to recommend a single therapy for this syndrome; however, this paradigm has recently changed, and the unmet clinical need for HFpEF treatment found a proper response as a result of a new class of drug, the sodium–glucose cotransporter 2 inhibitors, which beneficially act through the whole spectrum of left ventricular ejection fraction. The aim of this review was to focus on the therapeutic target of HFpEF, the role of new drugs and the potential role of new devices to manage the syndrome.
Nivel de Salud Mental Positiva en Equipos de Salud Mental de Tres Hospitales de Chile 2013
Authors: Vial M. Denisse , Rivas R. Edith , Bustos M. Luis
Published: April 2024

Introducción: La Salud Mental Positiva, se define como un estado de salud que gozan las personas, que encuentran un equilibrio entre lo que ellos esperan de la vida y lo que la vida les brinda, generando un sentimiento de felicidad, medido con la Escala de Lunch. El objetivo fue describir el estado de Salud Mental Positiva en el personal de los Servicios de Psiquiatría de tres Hospitales del sur de Chile, el año 2013. Metodología: Diseño de corte transversal, en universo de profesionales y técnicos que laboran en Servicios de Psiquiatría de tres hospitales. Recolección de los datos, a través de la Escala de Salud Mental Positiva de Llunch, (alfa 0.83). Análisis en frecuencias, porcentajes y comparación de promedios por prueba T test para varianzas iguales y distintas, según correspondió. Se apoyó con programa Stata 11.0v. Se cumplió con los resguardos éticos. Como resultado, se observó diferencias significativas entre la categoría funcionarios profesionales y no profesionales, en los dominios “satisfacción personal”, “relación interpersonal”, “resolución de problemas y autoactualización”, donde los funcionarios profesionales presentan estos factores ascendentemente más activos. Discusión y Conclusión: La satisfacción personal en los equipos, presenta una participación positiva. Se recomienda enfatizar en programas de prevención, vigilancia e intervención de salud mental en Organizaciones de Servicio Humano lo que permitiría contrarrestar efectos negativos y favorecía el desarrollo de valores prosociales.
Experiencia de un Caso en el Tratamiento del Síndrome de Mano Diabética por Absceso Dorsal
Authors: Altamirano Olvera Charles , Caicho Caicedo Oscar , Ramos Rojas Rocío , Mediavilla Ordoñez Darwin , Pérez Pérez Edgar
Published: April 2024

El objetivo de la presentación del siguiente caso, es destacar las bondades de la aplicación de la cura avanzada de heridas en el manejo de una lesión compleja de la mano. Decidimos presentar el caso de un paciente varón diabético que desarrolla un absceso en el dorso de la mano izquierda, su diagnóstico, tratamiento, evolución y el salvataje de su extremidad con la aplicación de apósitos, insumos y equipos para la cura avanzada de heridas de tercera y quinta generación en el servicio de Cirugía General del Hospital de especialidades Dr. Teodoro Maldonado Carbo, de la ciudad de Guayaquil en Ecuador. Considerando que la Diabetes es una enfermedad metabólica catalogada actualmente como pandemia por su alta prevalencia, alta inversión socio sanitaria; realidad que también nos involucra. Entre sus complicaciones agudas, se caracteriza por tener un rápido desarrollo, afectando e involucrando las estructuras osteo-musculo-tendinosas y los tejidos blandos de las extremidades, siendo la mano una de las estructuras de mayor riesgo y afectación, por lo que no está demás resaltar su importancia como unidad anatomo-funcional en la calidad de vida de una persona.
Extracting the Reference Test Suites from Cryptographic Protocol Specifications Written on a Domain-Specific Language
Authors: Prokopev Sergey Evgenevich
Published: April 2024

The paper describes a tool for testing the security of cryptographic protocol implementations working on the basis of specifications written in a declarative interoperable domain-specific language implemented as EDSL (Embedded [in Haskell] DSL). The problem of forming high-quality reference test suites for testing the security of cryptoprotocol implementations is considered. A method of addressing this problem within the tool being developed is discussed.
Luis López de Mesa, Ricardo Olano y la Campaña de Cultura Aldeana de 1935: predicar el civismo y el urbanismo para salvar los pequeños poblados
Authors: Schnitter Castellanos Patricia , Castrillón Gallego Catalina
Published: April 2024

Este artículo tiene como objetivo estudiar el papel que tuvo Ricardo Olano Estrada como promotor del urbanismo y el espíritu cívico en la Campaña de Cultura Aldeana, promovida por Luis López de Mesa, ministro de Educación de Colombia en 1934. Se explica en qué consistió dicha campaña y se destacan las ideas y propuestas impulsadas por Olano Estrada en los recorridos que tuvieron lugar por diferentes partes del país, así como la síntesis de su experiencia, la cual dio a conocer en la International Federation for Housing and Planning (IFHP) realizado en 1938 en Chicago. Para ello, se recurrió a la crítica de fuentes impresas como documentos del Ministerio de Educación, así como los escritos personales de Ricardo Olano, recogidos en su libro de memorias y demás textos publicados por él durante la década de 1930. Esto se complementó con la revisión de bibliografía relacionada con el tema de investigación. Se pudo concluir que la Campaña de Cultura Aldeana fue un ambicioso proyecto que buscaba la transformación integral de las llamadas aldeas o poblaciones menores, y en este sentido configuró una importante plataforma para la promoción de proyectos que buscaban su transformación a partir de una noción de urbanismo basada en el embellecimiento de los espacios por medio de la arborización y el cuidado de jardines; a lo que se sumaba la construcción calles y de vías de comunicación e infraestructura para el saneamiento urbano.
Kryzys zdrowia psychicznego dzieci i młodzieży – profilaktyka, pomoc
Authors: Matusiak Renata , Dębicka Agnieszka
Published: April 2024

Zdrowie psychiczne dzieci i młodzieży jest obecnie jednym z największych problemów w zakresie zarówno służby zdrowia, jak i profilaktyki szkolnej. Konstytucja Światowej Organizacji Zdrowia przyjęta w 1948 r. zdefiniowała zdrowie psychiczne jako „pełny dobrostan fizyczny, psychiczny i społeczny człowieka”, co do czasów obecnych stanowi punkt wyjścia w rozważaniach na temat istoty zdrowia człowieka 1 . Artykuł stanowi przegląd aktualnych rozważań dotyczących udzielania pomocy psychologiczno-pedagogicznej w szkole, osób udzielających pomocy, a także wybranych zaburzeń zachowania i emocji u dzieci i młodzieży. Pomoc dziecku w kryzysie i wspieranie go w trudnych sytuacjach ze względu na coraz większą powszechność problemów w zakresie zdrowia psychicznego u dzieci i młodzieży staje się również zadaniem szkoły i pracowników placówek oświatowych.
Mediacja i negocjacja NIE-doskonała
Authors: Wojtkowiak Monika
Published: April 2024

Mediacja i negocjacja to procesy, w których najważniejszą rolę odgrywa komunikacja. Pomimo różnic między nimi, istnieją podobieństwa zarówno w zakresie wykorzystania, jak i w odniesieniu do trudności, które mogą się pojawić. W artykule opisano wybrane bariery komunikacyjne (szczególną uwagę poświęcono umiejętności słuchania, brakowi dojrzałości, kłamstwu), które powinien znać każdy mediator i negocjator, mogące mieć znaczenie dla powodzenia rozwiązania konfliktu.
Samoocena poziomu kompetencji informatycznych przyszłych nauczycieli przedszkoli i klas I–III szkół podstawowych
Authors: Myśliwiec Katarzyna
Published: April 2024

Współczesna rzeczywistość i przemiany w niej zachodzące związane z rozwojem technologii informacyjno-komunikacyjnych warunkują nowe obszary przygotowania nauczycieli wszystkich szczebli edukacji, w tym także przedszkoli i klas I–III szkół podstawowych. W artykule przedstawiono wyniki badań prowadzonych wśród studentów III roku pedagogiki przedszkolnej i wczesnoszkolnej w obszarze kompetencji informatycznych. Respondenci dokonali samooceny w zakresie rozumienia podstaw informatyki, eksploatacji systemu komputerowego, komunikacji człowieka z komputerem, użytkowania urządzeń peryferyjnych oraz ochrony własności intelektualnej.
Kobieta: między tradycją a współczesnością. Samowychowanie do kobiecości
Authors: Grzybek Grzegorz
Published: April 2024

Modele tradycyjnej i współczesnej wizji kobiecości są sobie przeciwstawne i ukazują przemiany wrażliwości etycznej i religijnej. Pozytywne aspekty współczesnej wizji kobiecości, takie jak: „świadomość siebie i swoich możliwości” „wielozadaniowość” czy „niezależność”, podkreślają jej podmiotowość i konieczność podejścia dialogowego autorytetów społecznych i religijnych. Głównym zadaniem jednostki jest integracja etosu życiowego uwzględniającego współczesne przemiany i wizję siebie. Przemiany w sferze obyczajowej i społecznej roli płci w etosie życiowym mogą zostać zintegrowane między innymi przy przyjęciu „etycznego erotyzmu” odnoszącego się przede wszystkim do sfery aksjologicznej, nie zaś normatywnej. Pozwala to na zachowanie własnej podmiotowości i świadomego samowychowania.
Two-sample intraclass correlation coefficient tests for matrix-valued data
Authors:   Linnaeus University, School of Business and Economics, Department of Economics and Statistics, Liang Yuli , Hao Chengcheng ,   Shanghai University of International Business and Economics, China, Dai Deliang ,   Linnaeus University, School of Business and Economics, Department of Economics and Statistics
Published: April 2024

Under a model having a Kronecker product covariance structure with compound symmetry or circular symmetry, two-sample hypothesis testing for the equality of two correlation parameters is considered. Different tests are proposed by using the ratio of independent F distributions. Several tests are compared with the proposed ones and practical recommendations are made based on their type I error probabilities and powers. Finally, all mentioned tests are applied to a real data example.
EDUCAÇÃO FILOSÓFICA DAS APRENDIZAGENS
Authors: Tedesco Anderson Luiz , Benvenutti Dilva Bertoldi , Benvenutti Régis Carlos
Published: April 2024

Neste artigo, objetiva-se refletir acerca da relação existente entre educação filosófica e aprendizagem profissional docente. Para tanto, realizou-se uma pesquisa, de abordagem qualitativa, envolvendo estudos bibliográficos, apoiados em Benvenutti (2016, 2017), Gallo (2007, 2012), Maturana e Verden-Zöller (2004) e Morin (2000, 2008, 2015), entre outros. Os resultados indicaram para um despir formativo, para um profanar das fronteiras das formações patológicas do saber e das inteligências cegas, que são reproduzidas nos espaços de formação inicial e continuada da formação docente. Evidenciou-se, na educação filosófica para a formação docente, movimentos conceituais de sensibilização, problematização, investigação e conceituação. Conclui-se, portanto, que na educação filosófica é possível constituir saberes que não se fecham, mas permitem voos rizomáticos, saberes que se (re)constituem, (re)constroem experiências epistemológicas, éticas, estéticas e pedagógicas da formação docente.
Effects of non-linearity and thixotropy in linear amplitude sweep testing for the evaluation of self-healing of bituminous binders
Authors: Baglieri Orazio , Miglietta Fabrizio , Tsantilis Lucia , Santagata Ezio
Published: April 2024

Linear amplitude sweep tests have been demonstrated to have good potential in being used for the evaluation of self-healing properties of neat and polymer-modified bituminous binders. Past research works, however, have neglected the effects of material non-linearity and thixotropy. This implies that the whole material integrity loss is attributed to damage and all restoration to self-healing, thus resulting in the possible overestimate of both damage and self-healing when evaluating the fatigue performance of materials. In the study described in this paper, specific experimental and analytical methods were adopted with the purpose of separating non-linearity and thixotropy in LAS healing tests. Non-linearity was assessed by means of multiple strain sweep tests carried out to determine the material non-linear viscoelastic moduli at specific testing temperatures. Thixotropy was considered by coupling self-healing LAS testing with a purposely defined test in which loading was applied to the undamaged material after a rest period equal to that applied in self-healing tests. Obtained results were processed by means of an analytical approach based on the simplified viscoelastic continuum damage model. Quantification of self-healing included the determination of material integrity and damage parameters recovered after the rest period. Such parameters, calculated by excluding time-dependent and non-linear biasing effects, can be used as straightforward indicators of the self-healing potential of neat and polymer-modified bituminous binders. Moreover, obtained results substantiate the concept that time–temperature superposition is still applicable when non-linearity is incorporated into the simplified viscoelastic continuum damage model.
¡No me digás! Cali, su centro y sus vericuetos
Authors:   Universidad Cooperativa de Colombia, Holguin García Carlos Alberto
Published: April 2024

Esta reunión de ensayos literarios muestra algunos aspectos relacionados con la historia de Cali, desde su fundación hasta nuestros días, a partir de hitos arquitectónicos convertidos en sitios turísticos. Cada capítulo se desarrolla a partir del respectivo epígrafe, que señala el eje temático. Al final, a manera de anexo, hay una crónica sobre otro hito histórico, La Calle del Muerto, para mostrar su conversión en leyenda siguiendo pistas que no siempre fueron ciertas. Esta investigación informal, bien documentada y con buen sentido del humor, encontró que casi todos los sitios turísticos están relacionados con las familias tradicionales más poderosas de la ciudad cuyas fortunas se originaron en la tenencia de terrenos ejidos, en especial, los más costosos y mejor ubicados.
Implementación inicial de GORM: un ORM para GO
Authors:   Universidad Cooperativa de Colombia, Porras García Yerson Ferney , Patiño Martínez Francy Yaneth , Chica Sosa Piedad
Published: April 2024

El propósito de la presente guía es ilustrar al estudiante el proceso de implementación de GORM como herramienta ORM para la gestión de base de datos en una aplicación software realizada en el lenguaje de programación GO. Con un enfoque básico y sencillo que permite una implementación de un CRUD. Adicionalmente, se recomiendan algunas herramientas de software útiles para la codificación en GO. Finalmente, se define paso a paso la implementación de un modelo y su utilización y se presentan los parámetros para la elaboración y presentación del informe final.
Development of an Antioxidant-Rich Sugar-Free Plantain Candy and Assessment of Its Shelf Life in a Flexible Laminate
Authors: Sarkar Poulami , Bhattacharjee Paramita , Das Bidhan
Published: April 2024

Research background. Candy is a popular confection worldwide, and it would be beneficial to society if it were converted into a source of antioxidant molecules to eliminate its adverse health effects. The amount of antioxidants available even in fruit candies is questionable due to the high thermal processing losses they undergo and the presence of various food additives. Plantains (Musa paradisiaca) are less known as good sources of biotherapeutic antioxidants, namely l-tryptophan, serotonin and melatonin, and consumption of this highly nutritious fruit is limited to underdeveloped and developing countries. The objectives of this study are: to develop a functional antioxidant-rich sugar-free plantain-based candy with valuable contents of the mentioned biomolecules in synergy; and to ensure its extended shelf life without compromising its physicochemical properties and functionality by wrapping it with a suitable packaging laminate.
Experimental approach. To accomplish the first objective, lyophilized plantain powder, sorbitol and mannitol were used as base materials with minimal additives under minimal processing conditions to reduce processing loss. Sensory, proximate, physicochemical and phytochemical properties, including the antioxidant synergy among the mentioned biomolecules of the developed candies were evaluated. For the second objective, the candies were enclosed in two different flexible packaging laminates and the optimal packaging was determined based on the microbiological safety and sensory appeal of the wrapped candies. Subsequently, the above-mentioned properties of the packaged (in the most suitable laminate) candies were evaluated at regular time intervals during storage for assessment of their shelf life.
Results and conclusions. The candy had a characteristic flavour of plantain, uniform dark brown colour, rich mouthfeel, pleasant aroma, moderately hard texture and moderate sweetness, along with high antioxidant activity and considerable content of l-tryptophan, serotonin and melatonin (present as a synergistic consortium). During storage of the packaged candy under ambient conditions, it remained microbiologically safe for up to 56 days, and also maintained sensory attributes, antioxidant activity and synergy compared to the control candy.
Novelty and scientific contribution. This newly developed semi-hard sugar-free candy with high antioxidant content, containing three important antioxidants, namely l-tryptophan, serotonin and melatonin, could be a good source of biotherapeutic molecules and a substitute for commercial candies consumed globally.
Políticas de conservación de la Administración de Parques Nacionales (Argentina) mediante áreas protegidas, período 2000-2022
Authors: Caruso Sergio-Adrian
Published: April 2024

En Argentina, desde comienzos del siglo XXI, se ha detectado que las políticas de conservación desplegadas por la Administración de Parques Nacionales se han caracterizado por crear numerosas áreas protegidas y extender otras ya existentes. Durante estos años también tuvieron lugar dos procesos concurrentes. Uno de ellos, relacionado con la adopción y consolidación del neoextractivismo como modelo productivo, cuyas modalidades expoliaron las funciones ecosistémicas de las ecorregiones a lo largo de todo el territorio nacional. El restante, se asoció a los compromisos asumidos por el país ante el Convenio de la Diversidad Biológica mediante las Metas de Aichi. Por consiguiente, se plantea como hipótesis que ambos procesos condicionaron las políticas de conservación de dicho organismo durante el período 2000-2022. Se concluye que estas políticas resultaron reactivas y compensatorias al buscar proteger los relictos de las ecorregiones no erradicados por el neoextractivismo. A la vez, trataron de cumplir con los compromisos internacionales asumidos.
La heteronormatividad de la causal de divorcio por conducta homosexual en Chile: crónica de una derogación anunciada
Authors: Gauché Marchetti Ximena , Brevis Cartes Priscilla , Barría Paredes Manuel , Parodi Soto Valentina
Published: April 2024

Por sentencia de 27 de abril de 2021, el Tribunal Constitucional chileno declaró inaplicable por inconstitucional el artículo 54 No 4 de la Ley de Matrimonio Civil que contenía la causal de divorcio por conducta homosexual. En ese contexto, este trabajo ha tenido por objeto revisar tal causal de divorcio, finalmente derogada en Chile, para plantear una reflexión sobre las cuestiones de fondo de la sentencia, la evolución legislativa y el impacto en el reconocimiento del principio de igualdad y no discriminación frente a la heteronormatividad vigente en el ordenamiento jurídico chileno. En ese marco, 1) se analizó la situación del divorcio por conducta homosexual a la luz del principio de no discriminación, 2) se plantearon precisiones y reparos al texto de la sentencia del Tribunal Constitucional desde el parámetro del Derecho Internacional de los Derechos Humanos, y, 3) se contextualizó la decisión del Tribunal Constitucional y la posterior derogación de la norma con las reivindicaciones sociales de colectivos y organizaciones LGBTI en Chile. Se planteó así que, si bien existen avances, los desafíos normativos son aún mayores para erradicar la heteronormatividad y alcanzar el respeto al derecho a la igualdad y no discriminación desde un enfoque en Derechos Humanos.
Georges Bataille’s Atheology and Negative Sovereignty
Authors:   Lomonosov Moscow State University, Russian Federation, Siplivy Grigory
Published: April 2024

The article presents a brief essay on the analysis of three key concepts in the philosophy of Georges Bataille – heterology as the logic of exclusion, (a-)theology as an atheistic understanding of the death of God and the concept of ‘negative’ or ‘sacriﬁcial’ Sovereignty. It seems that the key to understanding the various and heterogeneous philosophical, literary-poetic, cultural-anthropological and socio-economic concepts of the French thinker is the prism of the heterological logic of exclusion, which opposes the internalization of the dominant ontological discourse. The heterology or ‘logic of exclusion’ used by Georges Bataille, is not so much a negative version of the traditional logic of ‘inclusion’, but is a logic of alternative extremes. It is precisely by striving to overcome the dominant metaphysical universalism of the general order of being (embodied, according to Bataille, in the concept of ‘being’ / ‘die Existenz’ in the philosophy of Martin Heidegger). In an effort to overcome the dominant metaphysical universalism of the general order of being, Bataille turns to various kinds of ‘denials’ and extremes – the left sacred or the sanctity of ‘foulness’, the metaphorical of the disgusting, erotic and violent forms of transgression, the cultivation of the experience of inner abandonment and ultimate despair, and, also, to his own concept of ‘sacriﬁce’, serving as a guide to the world of sovereign domination. Thus, developing his concept of metaphysical ‘sovereignty’, Bataille turns not only to the existential, but also to the political sphere, largely contrasting his ‘metaphysics of sacriﬁce’ with the concept of ‘metaphysical domination’ of the German political and legal theorist Carl Schmitt. The nihilistic energy drawn from Friedrich Nietzsche and the ‘metaphysical negation’ taken from Hegel’s dialectic through the interpretation of Alexander Kozhev is used by Bataille for the purposes of his own ‘heterological’ logic of exclusion, desubjectivization and dissolution. However, negation for Bataille is not a target for itself, but a methodological tool on the way to the ‘Other’ excluded from any ontosemantic order.
Changes in Boundaries within Human Society. On the Eve of Posthumanism
Authors:   Institute of Economics and Industrial Engineering, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Voronov Yury ,   Novosibirsk State University, Russian Federation
Published: April 2024

With the prevailing ideas of humanism in the public consciousness, many boundaries were created that divide people into categories. At the same time, on one side of the border there are those who are more deserving of the title ‘human’ in comparison with those who are on the other side. Over the course of history, these borders have been actively rebuilt, and the pace of their changes has become increasingly rapid in recent years. The article examines changes at ﬁve such boundaries: between men and women, according to belonging to different religious denominations, to different nationalities and races, between healthy people and disabled people (including between the mentally healthy and the crazy), as well as changes in attitudes over time to the homeless and tramps. The author considers the consequences of changes that have already occurred or are planned at each of these ﬁve boundaries. The author believes that a mandatory factor in global economic development has always been the “friendly-alien” division. With the help of such division in economic activity, trust is generated, which is the most important institution necessary for the existence and development of the economy and social organization. Trust facilitates the interaction of economic agents and facilitates the functioning of monetary mechanisms. Large-scale attempts to erase boundaries between people are being made through coups and revolutions, but they lead to the replacement of previously existing boundaries between people with new ones. An attempt to eliminate classes leads to the creation of a new system of boundaries - property inequality. An attempt to eliminate property inequality and the exploitation of man by man leads to the creation of a new system of boundaries – by the place in the vertical of power, by membership in the ruling party, and others. For this reason, with any reforms and radical transformations, it is advisable to anticipate the formation of new borders, and also to evaluate if they are much better than the previous ones in terms of social justice and economic efﬁciency.
Number Three in the Semiotics of Ch.S. Pierse. On the Issue of Triplicity
Authors:   Novosibirsk National Research State University, Russian Federation, Proskurin Sergey ,   Novosibirsk State Technical University, Russian Federation, Proskurina Anna ,   Novosibirsk State Technical University, Russian Federation
Published: April 2024

The number three refers to an important factor in the construction of the semiotics of Ch. S. Peirce. The number three is a kind of leitmotif of the theory. The whole construction of knowledge rests on primary, secondary and tertiary. Primary, secondary and tertiary are reduced to the three sides of Gottlob Frege’s triangle and appear in a different terminology as representative, object and interpretant. These ternary coordinates of thought are its space and embody, in the words of Yu. S. Stepanova, three-dimensional measurement of language. According to Ch. S. Pierce, these coordinates have a teleological meaning. The very concept of Ch. S. Pierce appears as the sum of three trichotomies, which allows twenty-seven combinations of signs, of which seventeen combinations are prohibited. Only ten combinations are allowed. The idea of trinity involves 310 sign complexes. Some of them are forbidden from the standpoint of logic. Thus, the index cannot serve as an argument. In the article, this is shown by the seating of subjects at a round table. The subject opposite appears to be on the right, but is actually opposite. The universality of the trinity appears as a reasoned code of semiotic construction. The triadic nature of the concept serves as the basis for constructing the laws of semiosis. Primary is iconic, secondary is indexical, and tertiary is symbolic. Questions of trinity arise as implementation of the narrative, when the ﬁrst is the beginning, the second is the end, and the third is the middle. The concept of three as the middle goes back to ancient art. The paper proposes an individual measurement of the middle as the third element. The counting tradition of the Indo-European peoples and the number of signs of the formula “faith, hope, love” are taken as the basis. The rearrangement of the elements of the formula, when the third in a row – love – occupies the middle second position, goes back to the earliest uses of this formula. This is the original approach to proving the middleness of the third in the tradition of the Indo-European peoples.
Lars von Trier’s Apocalyptic Consciousness in the Anthropology of the House That Jack Did Not Build
Authors:   Lomonosov Moscow State University, Russian Federation, Kon Vyacheslav
Published: April 2024

The subject of the study is the concept of the historical hero as a victor of the gods and his role in contemporary Western cultural heritage, with a focus on the reinterpretation of Scandinavian culture in the works of Lars von Trier. The research methodology is based on the analysis of Hollywood’s reception of neo-European rationalism and the ideas of individualism and free will in European culture. The author examines the inﬂuence of the implementation of freedom without morality on the exploration of the idea of the Übermensch (superman) and discusses unresolved questions in this context. The research ﬁndings highlight the importance of the themes of personal responsibility and freedom in Western culture, as well as the legacy of Scandinavian culture as a source of the manifestation of truths. The conclusions of the study emphasize the relevance and signiﬁcance of the discussed issues in the contemporary cultural context. The main goal of the research is to identify the consistent stages of Lars von Trier’s apocalyptic consciousness, particularly in the context of resistance to the colonization of art by ontological philosophy and the dominance of Hollywood clichés and political sentiments in the ﬁlm market. This work conducts a methodological investigation into how Lars von Trier applies the philosophy of images through cinematography as a tool to separate false and immaculate representations of the world, with a focus on the problem of sin in his composition. This work methodologically explores this process and analyzes how it interacts with contemporary culture and cinema. In the context of the scientiﬁc novelty of the research, a question arises about Lars von Trier describing himself as a ‘sadistic doctor’ who saves lives but remains, in the eyes of those saved, an antichrist and a criminal in the humanistic world and humanity’s defense of a world different from the existing one. The results of this research can be used to study philosophical anthropology in the ﬁeld of ﬁlm studies and visual arts, as well as in related social and humanitarian disciplines, to analyze how this theme interacts with culture and society.
Improvement of student’s argumentation skill through problem-based learning in the concept of nerveous and endocrine system disorders
Authors: Lutfiani Resti , Hamdiyati Yanti , Suhaeni Lilis
Published: April 2024

21st-century education directs learners to develop the skills of argumentation. Argumentation skills are the intellectual abilities involved in solving problems, making judgments and decisions, and formulating ideas and beliefs. The purpose of this research was to improve students' argumentation skills through the implementation of the Problem-based learning model in the concept of nervous and endocrine system disorders. This study was Collaborative Classroom Action Research with two learning cycles in the concept of Nervous and Endocrine System disorders. This study reveals students' argumentation skills adapted from Dawson Venville (2009). The results of this research revealed that the level of students' argumentation skills in cycle I was only up to levels 1 and 2. As much as 59% of students were at level 2 argumentation skills and 41% of students were at level 1 argumentation skills. In cycle II, there are students with level 3 argumentation skills. The rest scattered on levels 1 (3% of students) and 2 (35% of students) argumentation skills. Through this research, we found that students' argumentation skills increased from cycle I to cycle II.
Using a Drug Repurposing Strategy to Virtually Screen Potential HIV-1 Entry Inhibitors That Block the NHR Domain of the Viral Envelope Protein gp41
Authors: Andrianov A.M. , Laykov Y.V. , Tuzikov A.V.
Published: April 2024

Using a drug repurposing strategy, virtual screening of potential inhibitors of the NHR domain of the HIV-1 gp41 protein, a conserved region critical for the virus-cell membrane fusion and viral infectivity, was carried out. The used computational approach included: (1) molecular docking of this functionally significant region of the HIV-1 envelope with compounds from a library of bioactive molecules containing clinically approved drugs, experimental drugs, and investigational drug candidates; (2) assessing the binding affinity of these compounds to the therapeutic target; (3) molecular dynamics simulations of ligand/NHR-gp41 complexes; (4) calculations of the binding free energy followed by the analysis of molecular dynamics trajectories and selection of compounds promising to test for anti-HIV-1 activity. As a result, six compounds that exhibited the high binding affinity to the NHR domain of the HIV-1 gp41 protein and showed acceptable pharmacological properties were identified. The predicted compounds are assumed to form a promising basis for the development of new, effective and safe broad-spectrum antiviral agents able to inhibit the HIV-1 entry into the host cell.
A INTERAÇÃO ENTRE ADVOCACIA, LINGUAGEM JURÍDICA NA SOCIEDADE 5.0, VISUAL LAW E PRIVACY BY DESIGN
Authors: Menezes de Sousa Jéffson , Oliveira Santos Josyanne Maria
Published: April 2024

O presente artigo objetiva analisar a importância da utilização das técnicas do visual law e a aplicação do privacy by design no tratamento dos dados pessoais como instrumentos para assegurar a efetividade do consentimento livre e informado, com enfoque no impacto positivo da advocacia na linguagem jurídica. Para tanto, é analisada a hipótese legal do consentimento e os seus requisitos de validação pela Lei Geral de Proteção de Dados Pessoais brasileira (LGPD), bem como os desafios enfrentados pelo agente de tratamento quanto à legitimidade do uso do instituto, desde a sua coleta até o fim do processamento dos dados. A problemática reside na obtenção da manifestação livre e esclarecida do titular, uma vez que a informação acerca do tratamento nem sempre é clara e compreensível ao indivíduo, o qual possui uma hipervulnerabilidade informacional em razão do desconhecimento dos termos técnicos e jurídicos comuns no âmbito do tratamento de dados. Adota como hipótese a aplicação do privacy by design e do visual Law para conferir maior nível de transparência do tratamento dos dados pessoais e assim garantir a autodeterminação informativa. Para tal fim, procedeu-se a pesquisa bibliográfica e documental, de caráter qualitativo, pois busca compreender os conceitos teóricos e práticos do visual law e privacy by Design, bem como analisar e interpretar a legislação pertinente e as decisões proferidas pelo Poder Judiciário brasileiro. Destaca-se que estes mecanismos empoderam a tomada de decisão do titular na medida em que tornam a informação acerca do tratamento dos dados pessoais clara e objetiva.
The Pain of Modern Life: The Misery of Modern Existence
Authors: Ince Yenilmez Meltem , Kabakçı Günay Eylül
Published: April 2024

Social isolation and loneliness are posing more problems than ever. There are concerns that the long-term effects of loneliness will be felt when the COVID-19 outbreak reaches its third year. This study examines the prevalence and components of social isolation and loneliness across Europe. This study seeks to understand the effects of loneliness within a broad framework that may be used to guide anti-loneliness measures. This study also looks at why loneliness is important to study, the connection between loneliness and social isolation, future research on the topic, and interventions that could help with the problem of unequal exposure to loneliness and lack of assistance because of one's socioeconomic status.
GASTRONOMIC TOURISM IN THE TRANSCARPATHIAN REGION: DEVELOPMENT OF A TOURIST ROUTE
Authors:   Taras Shevchenko National University of Kyiv, Kyiv, Ukraine, Marymorych Anna
Published: April 2024

The increasing role of food and nutrition as a form of consumption, together with global processes in the world market, have led to the world's cuisines, along with the range of food products, becoming more accessible and in focus. This rapid development has led to an increase in interest in indigenous and unique foods, food products and culinary traditions, and this, in turn, has given rise to gastronomic tourism. More and more people are choosing to travel to try local cuisine or dishes from a local chef. During such tours, the consumer visits restaurants with local cuisine, participates in gastronomic events and cooking, learns about the history and recipes of local food and drinks, tastes drinks and travels to the places where the products of interest are grown, harvested and produced. Recently, cuisine has become an integral element of culture and lifestyle. It embodies all the traditional values associated with new trends in tourism: respect for culture and traditions, healthy lifestyles, authenticity, sustainability and the feelings associated with it. Gastronomy is also an opportunity to revitalise and diversify tourism. Promote local economic development involving different professional sectors, as well as the introduction of new technologies into the mainstream sector.The purpose of the study is to analyse the peculiarities of the regional Transcarpathian cuisine and identify the main gastronomic places of Transcarpathia, to compile and propose an author's gastronomic route of the region. The research methodology is based on the processing of analytical materials from various sources, as well as the use of scientific methods of analysis and synthesis. The tabular method allowed us to summarise the data. Results. The article analyses the regional cuisine of the Zakarpattia region and identifies the unique features of local cuisine. The main gastronomic places and events of Transcarpathia are outlined. The author's two-day gastronomic route through the region is proposed. Scientific novelty. Gastronomic places and events in the Transcarpathian region are summarised. The features of the regional cuisine of Transcarpathia are revealed. Practical significance. The results obtained can be used to develop a strategy for the development of gastronomic tourism in Transcarpathia. In addition, the materials of the article can be used in tourism activities by those wishing to travel to Transcarpathia, including travel agents.