bluuebunny/crossref_metadata_2025 huggingface dataset:
A New Parameter for Dynamic Response Evaluation
Authors: Hirahata Tomoki , Hashimoto Shuichi , Watanabe Hiroaki , Yagi Shin-Ichi , Edanaga Mitsutaka , Yamakage Michiaki
Published: March 2023

Purpose
Obtaining accurate invasive blood pressure readings requires excellent dynamic response of the pressure monitoring circuit. In 2006 and 2020, we reported that Gardner's natural frequency and damping coefficient, which are widely used as evaluation methods, do not reflect the dynamic response of the circuit. Therefore, we propose a new parameter for evaluating the dynamic response of a pressure monitoring circuit.
Methods
A blood pressure wave calibrator, two pressure monitors with analog output and a personal computer were used to analyze blood pressure monitoring circuits. All data collection and analytical processes were performed using our step response analysis program. Arterial pressure catheters with length of 30, 60, 150, and 210 cm were prepared to investigate "gain at 10 Hz" and systolic blood pressure changes.
Results
The gain at 10 Hz was close to 1 and the systolic blood pressure difference was small in the short circuits (30 cm, 60 cm), and the gain at 10 Hz was 1.3–1.5 in the 150 cm circuit and over 1.7 in the 210 cm circuit. The difference in systolic blood pressure increased in proportion to the length of the circuit.
Conclusions
The necessary gain at 10 Hz is determined by how much difference in systolic blood pressure is acceptable. Clinically, a difference of 5 mmHg or less is considered acceptable. Therefore, in order to satisfy this condition, the gain at 10 Hz must be 1.2 or less. The gain at 10 Hz is sufficiently useful as an index for obtaining correct blood pressure.
The Power Indices for Simple Games and the Differential Power Property
Authors: Masuya Satoshi
Published: March 2023

Many power indices for simple games are proposed.
Among them, the Shapley-Shubik index and the Bahzhaf index are
well-known. The study of axiomatizations of a power index
enables us to distinguish it with other indices.
Hence, it is essential to know more about the axioms of power indices.
Almost all the power indices proposed so far satisfy the axioms of Dummy, Symmetry and
Efficiency. Thus, those three axioms can be
interpreted fundamental axioms for power indices.
In this paper, we investigate those indices which satisfy the three axioms and propose a new axiom which is said to be Differential Power property.
It claims that if a minimal winning coalition $T$ is added to a simple game, then the same amount of power
is added to each member of $T$ and $N\setminus T$ in the new game. We axiomatize the Shapley-Shubik index,
the Banzhaf index and the Deegan-Packel index
using the Differential Power property. However, it turns out that the Johnston index does not satisfy this property.
Hence, as the next problem, we investigate that whether there are other indices which do not satisfy Differential Power property but satisfy the three fundamental axioms.
Szellemi rekreáció egy tematikus útvonal kapcsán – „Csodarabbik útja”
Authors: Rozgonyiné Drotár Nikolett , Nagy Adrienne , Petykó Csilla , Szalók Csilla
Published: March 2023

Tokaj-Hegyalját 2017-ben a magyar kormány kiemelt turisztikai fejlesztési területté nyilvánította. A terület turisztikai imázsának alapját az oxidatív borkészítési hagyományok (UNESCO Világörökség) mellett a terület történelmi, vallási, kulturális és sokszínű természeti értékei adják. Mindez gazdag rekreációs potenciál. Az utóbbi 15 évben jelentős kínálatfejlesztés ment végbe a turizmus szinte minden területéhez kapcsolódóan, mely a vendég- és látogatószám növekedésében (kereslet) is kimutatható. Kutatásunk a gazdag adottságokból a csodarabbi mítoszhoz kötődő vallási útvonalat vizsgálja, fókuszban a szellemi rekreáció lehetőségeivel. A szellemi vagy mentális, intellektuális aktvitások is nélkülözhetetlenek frissességünk megőrzésében. A hitélet egyértelműen szellemi rekreációs tevékenység és utazási motiváció. A tematikus útvonalnak köszönhetően a terület felkerült a zsidó vallási turizmus nemzetközi térképére, és ez a vallási örökség jelentős turistaforgalmat generál a térségben. Tokaj-Hegyalján új turisztikai termék született.
Computation-Guided Support to Experiments by the Exploration of Reaction Mechanisms: Organic Synthesis, Natural Products and Environmental Issues
Authors: de Andrade Karine , Fajardo José Renato , Leal Caio , Carneiro José Walkimar , Fiorot Rodolfo
Published: March 2023

Humankind has experienced a remarkable development since it began to design and optimize chemical reactions to achieve valuable compounds. The key to accomplish these tasks is the proper understanding of how chemical transformations occur at a molecular level, that is, their reaction mechanisms. Based on a suitable mechanistic proposal, experimentalists choose a given chemical protocol to optimize experimental conditions, design new synthetic routes, and circumvent competing reactions. In this context, computational chemistry has become a valuable ally for mechanistic elucidation. We present herein a review of complementary collaborations between experimentalists and theoretical chemists to rationalize processes at the molecular level, focusing mainly on the fields of organic synthesis, natural product chemistry, and systems with environmental interest. Throughout this review, we highlight the ability of computational evaluations to provide answers to questions raised from experiments in a clear and direct way, indicating to experimentalists alternative paths to help them solve their problems.
COVID 19 Pandemi Sürecinde Öğretmenler ve Medya Okuryazarlığı
Authors: ÜSTÜNDAĞ Alev
Published: March 2023

COVID-19 pandemi süreci tüm hayatı farklı şekillerde etkilemektedir. Medyanın pandemi nedeniyle hayatımız üzerindeki artan etkisi, öğretmenlerin geleneksel eğitim yöntemlerinin dışında, ders içeriklerinin sunum yöntemlerinin yeniden değerlendirilmesine sebep olmuştur. Bu nedenle de yapılan araştırmada farklı eğitim kademelerde görev yapan öğretmenlerin medya okuryazarlık becerisi düzeylerinin belirlenmesi ve çeşitli değişkenlere göre incelenmesi amaçlanmıştır. Nicel araştırma deseniyle oluşturulan çalışmada, nicel araştırma yöntemlerinden betimsel araştırma yöntemi kullanılmıştır. Araştırmanın örneklem grubunda farklı eğitim kademelerinde görev yapan 120 öğretmen bulunmaktadır. Araştırma verileri kişisel bilgiler formu ve Medya Okuryazarlığı Becerileri Ölçeği kullanılarak elde edilmiştir. Verilerin analizinde bağımsız gruplarda t testi ve tek yönlü varyans analizi (ANOVA) yapılmıştır. Araştırmanın sonucu genel olarak değerlendirildiğinde öğretmenlerin medya okuryazarlığı düzeylerinin yüksek olmadığı belirlenmiştir. Ayrıca öğretmenlerin medya okuryazarlık becerileri düzeylerinin cinsiyete ve çalışma yılına göre farklılık göstermediği, ancak görev yapılan eğitim kademesine göre farklılık gösterdiği belirlenmiştir. Genel olarak öğretmen-öğrenci-eğitim bağlamında etkileşimin güçlendirilmesi ve sürdürülmesini sağlayan medya araçları ve uygulamalarına odaklanmak gerekmektedir.
Conceito força
Authors: Roncaglio Viviane , Nehring Cátia Maria , Battisti Isabel Koltermann
Published: March 2023

Esse estudo tem por objetivo, a partir de uma revisão bibliográfica, constituir um aporte teórico que possibilita a compreensão do conceito Força como uma grandeza vetorial, a partir do campo e das relações conceituais que o constituem. Para tanto, consideramos como material de análise as definições de força apresentadas em capítulos de livros da bibliografia básica das disciplinas de Física I e Mecânica Geral I de um Curso de Engenharia Civil. A fundamentação teórica que sustenta a escrita é a Teoria Histórico-Cultural. O percurso metodológico utilizado é a Análise Textual Discursiva de Moraes e Galiazzi (2016), a partir da qual constituímos as unidades de significado, as categorias e as proposições. A partir das análises realizadas, concluímos que a abordagem dada ao conceito força está fortemente relacionada a uma grandeza vetorial e às noções intuitivas de empurrar ou puxar.
Novos caminhos, velhas rotas
Authors: Braido Luiza da Silva , Castaman Ana Sara , Ferreira Liliana Soares
Published: March 2023

Este estudo visa a analisar os movimentos de sentidos evidenciados no Programa Federal “Novos Caminhos” para a Educação Profissional e Tecnológica (EPT). Para tanto, fundamenta-se teórica e metodologicamente na Análise dos Movimentos de Sentidos. Descreve a EPT com base na educação e no trabalho, a partir de fundamentos ontológicos, e a caracteriza conforme os sentidos evidenciados pelo Programa em análise. Do mesmo modo, criticamente, deslinda os sentidos produzidos a partir das potencialidades e das estratégias do “Novos caminhos”, quando cotejados com os contextos social, econômico e político em que são constituídos. Como resultados, percebeu-se que o Programa “Novos Caminhos” conduz a “velhos rumos”, já abordados desde 1970, com a Teoria do Capital Humano. Todavia, atualizados com as necessidades do momento histórico vivido, esses caminhos reforçam perspectivas neoliberais que fortalecem também o contexto capitalista e intensificam a precarização do trabalho pedagógico e o sucateamento da educação.
Operacionalização da meta 4 do PNE (2014/2024) no estado do Amazonas
Authors: Matos Maria Almerinda de Souza , Lemos Cátia de
Published: March 2023

Os estudos do artigo integram os resultados de uma das categorias da Tese intitulada: A implementação da meta 4 do Plano Nacional de Educação (2014/2024) em 18 Planos Municipais de Educação no estado do Amazonas. Objetivou-se investigar como ocorreram as ações para operacionalizar o PNE no território nacional em consonância/dissonância com a Política Nacional de Educação Especial na Perspectiva da Educação Inclusiva – PNEEPEI (2008). Ao analisar as estratégias para atingir a Meta 4 do PNE, foi possível descobrir se ocorreu ou não a implementação dessa política nos municípios investigados. Utilizou-se uma abordagem qualitativa, com pesquisa bibliográfica na legislação pertinente e entrevistas semiestruturadas com 25 agentes educacionais. Considerou-se, portanto, que a pesquisa revelou entraves como a ausência de cooperação técnica entre os entes federados, a escassez de salas de recursos multifuncionais e os baixos investimentos de recursos financeiros na educação especial, negligenciando a efetiva implementação das ações previstas pelo PNE (2014/2024).
Criação e imaginação
Authors: Barros Marta Silene Ferreira , Vicentini Dayanne , Ferreira Ana Letícia , Cortez Maíra Dellazeri , Garcia Natália Navarro
Published: March 2023

O presente estudo emergiu das discussões acerca da formação da criança com a finalidade de analisar o processo de criação e imaginação na infância a partir da modelagem em argila enquanto atividade importante no desenvolvimento infantil. A temática torna-se relevante para ampliar o repertório cultural da criança, bem como aumentar as capacidades de criar e imaginar, características tipicamente humanas, as quais necessitam ser estimuladas para a formação da consciência. A análise subsidia-se no método crítico dialético e na Teoria Histórico-Cultural, com vistas a ressaltar o papel da imaginação na formação das funções psíquicas superiores. Os resultados revelaram que o trabalho com a argila na Educação Infantil permite a criança transitar da concretude do material às representações mais abstratas da realidade objetiva. Portanto, o ato transformador realizado na atividade com a arte possibilita à criança participar ativamente da ação humana na relação que estabelece com a natureza.
Preparation and Characterization of PLGA-based Magnetic Polymer Nanoparticles
for Targeting Pancreatic Adenocarcinoma
Authors: Lu Liangji , Jie Liyong , Zhou Ying , Zhang Jiaojiao , Feng Tingting , Zhu Yue , Chen Teng , Zhu Xiuliang , Ji Jiansong , Wang Zuhua
Published: March 2023

Aims:

This study aims to develop a novel tumor-targeted molecular probe for pancreatic cancer imaging.
The objective of this is to prepare a CKAAKN peptide-conjugated poly (lactic-co-glycolic acid)-poly (ethylene
glycol) amphiphilic polymer (CKAAKN-PEG-PLGA) for the tumor-targeted delivery of magnetic resonance
imaging (MRI) contrast agent ultrasmall superparamagnetic iron oxide (USPIO).

Background:

The early diagnosis of pancreatic cancer is crucial for improving its prognosis, but the clinical application
of many diagnostic methods is limited owing to a lack of specificity and sensitivity.

Methods:

CKAAKN-PEG-PLGA was synthesized by the amidation reaction. USPIO-loaded polymeric magnetic
nanoparticles (USPIO@CKAAKN-PEG-PLGA) were prepared by the emulsion solvent evaporation method.
The in vitro tumor targeting and bio-safety of nanoparticles were evaluated by targeted cellular uptake, MR
imaging and MTT assay.

Results:

USPIO@CKAAKN-PEG-PLGA nanoparticles showed excellent biosafety with an average diameter
of 104.5 ± 4.1 nm. Modification of CKAAKN peptide could improve USPIO binding ability to internalize into
CKAAKN-positive BxPC-3 cells compared with non-targeting nanoparticles and the control group. The relative
fluorescence intensity in BxPC-3 and HPDE6-C7 cells was 23.77 ± 4.18 and 6.44 ± 2.10 (p < 0.01), and respectively
became 16.13 ± 0.83 and 11.74 ± 1.74 after the addition of free CKAAKN peptide. In vitro MR
imaging studies showed that an obvious decrease in the signal intensity was observed in the targeted nanoparticles
group incubated with BxPC-3 and HPDE6-C7 cells (p < 0.05).

Conclusion:

USPIO@CKAAKN-PEG-PLGA nanoparticles could significantly enhance the tumor specificity
of USPIO in CKAAKN-positive pancreatic cancer cell BxPC-3, which is expected as a promising candidate of
MRI contrast enhancement for the early diagnosis of pancreatic cancer.
Diseño de un vehículo para la competición Shell Eco-Marathon
Authors: Vega Cáceres Brayan Steven , Díaz García Edwin David , Ardila Gómez Sergio Andrés
Published: March 2023

La eficiencia energética ha ido ganando relevancia a lo largo de los años; por ello, las grandes empresas tratan de promover la investigación y el desarrollo a través de la sana competencia. Shell Eco-Marathon promueve el desarrollo de la eficiencia energética, a través de una carrera de vehículos en circuito cerrado, donde estudiantes universitarios diseñan y construyen vehículos desde cero. Con el fin de generar conocimiento en esta área, los estudiantes de la Universidad Autónoma de Bucaramanga realizaron el diseño de un vehículo bajo el reglamento vigente de la competencia para el año 2022. Para esto, se diseñó un chasis tubular en SolidWorks que se sometió a diferentes pruebas de resistencia mecánica en comsol. Posteriormente, se diseñó el sistema de dirección según la geometría de Ackerman y, finalmente, se desarrolló la carrocería del vehículo en SolidWorks a la que se le realizó un estudio aerodinámico en Ansys Fluent.
FEATURES OF THE FORMATION OF THE ARCHITECTURE OF TOURIST OBJECTS IN THE AZOV RESORT AND RECREATIONAL ZONE OF THE KRASNODAR TERRITORY
Authors: BALAKINA ALEVTINA , FEDOROVA SOFYA
Published: March 2023

The affordable cost of recreation on the Azov coast, as well as the presence of the sea, combined with a favorable climate, make these territories attractive for Russian tourism. However, more than half (62%) of all accommodation facilities in the regions of the Azov region are individual accommodation facilities: small private guest houses, which provokes a number of problems. The state of the resort and tourism industry in the Azov resort and recreational zone is a very topical issue, but most studies present an assessment of the current state of the resort and tourism industry from the point of view of related sciences. In this regard, the purpose of the study is to determine the features of the formation of the architecture of tourist facilities for this region, and its tasks can be determined: identifying the most developed and resort-oriented areas of the Azov region, studying iconic accommodation facilities in selected areas, systematizing the collected material, taking into account the main factors (natural and climatic, functional-planning, socio-economic) and their criteria (climate type, temperature, air humidity and terrain; typology of accommodation facilities, territory development system; capacity index of resort complexes, seasonality of work) that affect tourist attractiveness. The practical significance of the study is related not only to identifying the strengths and weaknesses of the development of the resort in this region, but also to predicting the tourist attractiveness of the Sea of Azov regions. The analysis allows you to determine which of the existing accommodation facilities will be popular and attractive to tourists in the near future, and which of them require urgent modernization. The totality of the results obtained shows the presence of real opportunities for the sustainable development of the Azov region as a resort
ANALYSIS OF THE URBAN HEAT ISLAND USING MICROCLIMATE SIMULATION FOR URBAN QUARTER
Authors: Kornienko Sergey , Dikareva Ekaterina
Published: March 2023

This study demonstrates that the development of green infrastructure is an important task in the formation of ur-ban planning strategies to reduce the effect of the urban heat island and improve the ecosystem of the city. Simulation is an effective method for studying the complex mechanisms of urban climate formation at the stage of urban planning. The purpose of this study is to assess the severity of the urban heat island in relation to the quarter, taking into ac-count various scenarios of its landscaping, using modern simulation tools. Based on modeling in the ENVI-met soft-ware and computing complex of the thermal conditions of the quarter on the hottest days, its high thermal heterogenei-ty was established. The maximum temperature values are noted in roads and soils, the minimum – in green areas. The temperature conditions of the quarter changes over time. Exceeding the average temperature of the urban quarter ter-ritory over the average temperature in green areas means the possibility of forming an urban heat island. The calcula-tion established that most of the quarter is located in the urban heat island zone. This is also confirmed by an increase in air temperature in an urbanized area. Recommendations are given to mitigate the urban heat island. Based on the results of the thermal simulation of the quarter, it was established that the most effective solution compared to the orig-inal model is an increase in the area of lawn grass and shrubs by 10%, an increase in the area of trees by 12% and a decrease in asphalt pavements of paths and sites by 5.7%. Such a solution maximizes the mitigation of the urban heat island and provides a high level of comfort for the urban environment. Further research will focus on the development of a multi-factor correlation-regression model to assess the mitigation effect of urban heat islands by means of improv-ing green infrastructure.
DERİN ZEMİN KARIŞTIRMA YÖNTEMİNDE NİHAİ TAŞIMA GÜCÜNÜN BELİRLENMESİ
Authors: DİKMEN Mukaddes Tuğçe , KESKİN Nilay
Published: March 2023

Bu çalışmada, Amasya İli, Merkez İlçesi’nde inşaası yapılan konut türü yapı için temel zemini ıslahında uygulanan derin zemin karıştırma yönteminin incelemesi gerçekleştirilmiştir. Derin zemin karıştırma yöntemi, mevcut problemli zeminlere çeşitli mekanik şaftlar vasıtasıyla katkı maddelerinin (bağlayıcı) enjekte edilerek karıştırılması esasına dayanır. Yöntem, kohezyonsuz zeminlerde genel olarak taşıma kapasitesi artırmak, oturmaları ve sıvılaşma potansiyelini azaltmak amaçlarıyla uygulanabilir. Bu çalışma kapsamında; taşıma gücü ve sıvılaşma problemi beklenen temel zemini için 80 cm çapında ve 15,00 metre boyunda derin zemin karıştırma kolonları tasarlanmıştır. Sahada yapılan statik eksenel yükleme deneyinden elde edilen sonuçlara göre literatürde yaygın olarak kullanılan Brinch Hansen %80, Chin Kondner, Decourt, Mazurkieicz ve Hirany Kulhawy yöntemleri ile derin karıştırma kolonu için nihai taşıma kapasitesi belirlenmiştir. Ayrıca tekil derin karıştırma kolonu Plaxis 3D Foundation sonlu elemanlar yazılımıyla modellenerek taşıma kapasitesi tahmini yapılmıştır. Sonuç olarak; teorik olarak hesaplanan taşıma kapasitesi değerine en yakın sonucu Mazurkieicz yöntemi vermiştir. Brinch Hansen %80 yönteminde ise düşük taşıma kapasitesi elde edilmiştir.
ÜRÜN GÜVENLİĞİ DENETİMİNDE UYGULANAN İDARİ PARA CEZALARININ TESPİTİ İÇİN AHP TEMELLİ BİR MODEL ÖNERİSİ
Authors: METE Mevlüt Hürol , KARADEMİR Kağan
Published: March 2023

Çalışma kapsamında, Sanayi ve Teknoloji Bakanlığı sorumluluğunda yürütülen piyasa gözetimi ve denetimi faaliyetleri sonucunda, ilgili yasal yükümlülüklerine uymayan sorumlulara karşı uygulanan idari para cezaları incelemeye konu edilmiştir. Bu kapsamda, piyasanın düzenlenmesi, ürün güvenliğinin sağlanması ve haksız rekabetin önlenmesi için yükümlülüklerini yerine getirmeyen sorumlulara karşı caydırıcı bir araç olarak kullanılan idari para cezası tutarlarının bilimsel şekilde hesaplanması amacıyla kurgusal bir model geliştirilmiştir. Çalışmada nitel araştırma yöntemlerinden derinlemesine görüşme ve odak grup görüşmeleri vasıtasıyla idari para cezasına etki ettiği düşünülen kriterler belirlenmiş ve gruplandırılmıştır. Tespit edilen kriterlere ilişkin Analitik Hiyerarşi Prosesi (AHP) tekniği ile kriter ağırlıkları belirlenerek çalışma kapsamında üssel yöntem yaklaşımı olarak belirlenen hesaplama ile model kurgusu tamamlanmış ve test edilmiştir. Geliştirilen model ile idari yaptırıma konu olan ürünler ve bunları piyasaya arz eden firmalar belirli faktörler çerçevesinde puanlanabilmektedir. Bu puanlar aracılığıyla herhangi bir vaka karşısında ceza uygulayıcısının referans alabileceği bir hesaplama yöntemi geliştirilerek İPC tutarının tayininde kullanılabilecek bir model önerilmiştir.
İKLİM DEĞİŞİKLİĞİ ETKİSİ ALTINDA BURDUR GÖLÜ SU SEVİYESİ DEĞİŞİMLERİNİN İSTATİSTİKSEL OLARAK İNCELENMESİ
Authors: PINARLIK Murat , İBİŞ Abdulkadir , SELEK Zeliha
Published: March 2023

Türkiye için küresel ısınma etkisi ile yağışların azalacağı, buharlaşma ve sıcaklık değerlerinin artacağı tahmin edilmektedir. Bu etkenler göz önüne alındığında göl, rezervuar gibi su kütlelerinde ciddi seviye ve hacim düşüşleri meydana gelebilecektir. Bu çalışmada, Burdur Gölü ele alınarak iklim değişikliği etkisi altında göl su seviyesindeki değişimler incelenmiştir. İlk olarak, 1975-2020 yılları arasındaki göl parametreleri ile iklim parametreleri arasındaki ilişki korelasyon yöntemi ile irdelenmiştir. Daha sonra, 2021-2050 yılları arasındaki göl seviye ve hacim değişim tahminlerine iklim projeksiyonu tahminleri eklenmiştir. İklim projeksiyonlarına göre sıcaklığın referans döneme göre %11,38 arttığı, yağışların %4,5 azaldığı ve buharlaşmanın ise %15 arttığı görülmüştür. Yapılan analizler sonucunda Burdur Gölü su seviyesinin 1975-2020 periyodunda düşüş trendinde olduğu ve bu durumun 2021-2050 periyodunda devam edeceği gözlenmiştir. Ayrıca, yapılan korelasyon analizleri sonucunda göl seviyesi ile buharlaşma arasında (-0,6452) negatif yönlü orta derecede anlamlı ilişki, göl seviyesi ile yağış arasında ise (-0,1066) negatif yönlü çok zayıf derecede ilişki olduğu belirlenmiştir.
ENTEGRE BİR TEKSTİL İŞLETMESİNDE KİMYASAL AZALTIMI VE KİMYASAL DEĞİŞİMİ UYGULAMASI
Authors: ÖZTÜRK Emrah
Published: March 2023

Bu çalışmada ağırlıklı olarak pamuklu dokuma ve örgü kumaş üretimi yapan entegre bir tekstil işletmesinde kimyasal tüketimlerinin azaltılması ve çevresel açıdan riskli kimyasalların çevre dostu ikameleriyle değişimi amaçlanmıştır. Tesiste yerinde detaylı incelemeler ve veri toplama çalışmaları yapılmıştır. Prosesler bazında spesifik boyarmadde ve spesifik yardımcı kimyasal tüketimleri hesaplanmıştır. Tesisin spesifik boyarmadde ve yardımcı kimyasal tüketimleri literatürde ve Entegre Kirlilik Önleme ve Kontrol (IPPC) Tekstil Sektörü için Mevcut En İyi Teknikler Referans Dokümanında (BREF) yer alan benzer tesis verileriyle kıyaslanmıştır. Böylelikle tesisin boyarmadde ve kimyasal kullanımı açısından azaltım potansiyelleri değerlendirilmiştir. Ayrıca tesiste toplam 450 kimyasalın malzeme güvenlik bilgi formları (MGBF) biyodegradasyon oranları, toksik özellikleri ve mikrokirletici içerikleri açısından incelenmiştir. Buna göre 48 kimyasalın çevresel açıdan riskli olduğu belirlenmiş ve çevre dostu ikameleriyle değişimleri önerilmiştir. Tesiste yürütülen saha çalışmaları ve veri analizi çalışmaları sonucunda elde edilen bilgilerden yararlanılarak tesis yönetimi ve teknik personeliyle birlikte 10 adet kimyasal azaltım tekniğinin uygulanmasına karar verilmiştir. Belirlenen her bir teknik için azaltım oranları, yatırım maliyetleri ve geri ödeme süreleri belirlenmiştir. Tesiste belirlenen tekniklerin tümünün uygulanmasıyla boyarmadde ve yardımcı kimyasal tüketimlerinde %14,9-27,3 arasında azaltım sağlanabilineceği bulunmuştur. Uygulamaların geri ödeme süresinin 41 aydan daha kısa olacağı hesaplanmıştır.
UÇUCU KÜL, SİLİS DUMANI VE TÜF İLE STABİLİZE EDİLMİŞ BENTONİTTE MEYDANA GELEN MOLEKÜLER DEĞİŞİMLERİN FOURİER DÖNÜŞÜMLÜ KIZILÖTESİ SPEKTROSKOPİSİ (FT-IR) YÖNTEMİ İLE BELİRLENMESİ
Authors: ASLAN TOPÇUOĞLU Yasemin , GÜROCAK Zülfü
Published: March 2023

Kolay uygulanabilir ve ekonomik bir yöntem olması nedeniyle günümüzde çok fazla tercih edilen stabilizasyon, killi zemine eklenen katkı malzemesi ve zemin arasında oluşan puzolanik reaksiyonların bir sonucu olarak meydana gelmektedir. Oluşan puzolanik reaksiyonlar ise zeminde moleküler değişimlere neden olmaktadır. Bu değişimleri belirlemenin en yaygın yolu ise Fourier Dönüşümlü Kızılötesi Spektroskopisi (FT-IR) yöntemidir. Bu çalışmada, katkı malzemesi olarak uçucu kül ve silis dumanı ile asidik ve bazik tüfler kullanılarak hazırlanan ve 28 günlük kür uygulanan örneklerde FT-IR çalışmaları yapılmış ve stabilizasyon sonrası meydana gelen moleküler değişimler incelenmiştir. Analizler sonucunda bazik tüfün kullanıldığı örnekte, (Ca, Mg) CO3 gerilimiyle ilişkili olan 1431 cm-1’de yeni bir pik oluşmuştur. Uçucu külün kullanıldığı örnekte CaO oranı etkisiyle gelişen puzolanik reaksiyonlar sonucunda oluşan C-S-H ve C-A-S-H bileşikleri ile ilişkili 1416 cm-1 dalga sayısında oluşan yeni bir pik belirlenmiştir. Silis dumanı ve bazik tüfün birlikte kullanıldığı örnekte 1363 cm-1 ve 1431 cm-1 dalga sayılarında yeni pikler oluşmuştur ve bu pikler (Ca, Mg) CO3 gerilimiyle ilişkilidir. Asidik tüf ve uçucu külün kullanıldığı örnekte ise C-S-H ve C-A-S-H bileşikleri formunda kalsit oluşumu ile ilişkili 1363 cm-1 ve 1416 cm-1 dalga sayılarında iki yeni pik meydana gelmiştir. Çalışmanın sonuçlarına göre puzolanik reaksiyonların en iyi geliştiği örnekler %10 bazik tüf ve %10 silis dumanı ile %10 asidik tüf ve %10 uçucu kül katkılı örneklerdir.
İSTANBUL AVRUPA YAKASINDA MEYDANA GELEN SİSMİK OLAYLARIN KAYNAK TÜRLERİNİN BELİRLENMESİ
Authors: YAVUZ Evrim
Published: March 2023

Nüfus, sanayi, yapılaşma ve turizm açısından ülkemizin en yoğun kenti olan İstanbul, tektonik olarak, güneyinde uzanan Ana Marmara Fayı’nın kontrolü altındadır. Endüstriyel hammadde ihtiyacı ise Avrupa Yakasındaki taş ocağı işletmeleri tarafından sağlanmaktadır. Dolayısıyla, bölgede hem doğal hem de yapay kaynaklı mikro-sismik aktivite gözlenmektedir. Olayların enerji içeriği, sismik istasyon sayısının/dağılımının yeterli olmaması ve dalga fazlarının doğru seçilememesi vb. nedenlerden dolayı da kaynak türleri tanımlanmasında hatalar gözükebilmektedir. Daha güvenilir kaynak türü belirlenmesi ise ikincil analizler ile yapılmaktadır. Çalışmada, İstanbul Avrupa Yakası’nda 2007-2021 yılları arasında meydana gelen, büyüklüğü M≤2.8 olan 195 adet sismik olayın Boğaziçi Üniversitesi Kandilli Rasathanesi ve Deprem Araştırma Enstitüsü Bölgesel Deprem ve Tsunami İzleme Merkezi (KRDAE-BDTİM) tarafından işletilen altı adet deprem istasyonunda kayıt edilen 270 adet dalga formu için kaynak türü belirleme analizleri yapılmıştır. Olayların kaynak türleri katalog bilgilerinden bağımsız şekilde, görsel olarak belirlenerek yola çıkılmıştır. Düşey bileşen sismogramları kullanılarak, genlik oranı ve karmaşıklık yöntemleri uygulanmıştır. İstatistiksel sınıflandırma için Lineer ve Karesel Ayrımlaştırma Fonksiyonları kullanılarak, yöntem bazlı başarı oranları hesaplanmıştır. Sonuç olarak, 195 adet sismik olayın, 28 tanesinin deprem, 167 adetinin patlatma kaynaklı olduğu tespit edilmiştir. Daha güvenilir kaynak türü tanımlaması ile homojen kataloglar oluşturulmakta ve depremsellik, deprem tehlike analizleri gibi çalışmalarda araştırmacıların ikincil analizler ile zaman kaybı yaşamasının önüne geçilebilmektedir.
The Use of Digital Health Services Among Patients and Citizens Living at Home: Scoping Review
Authors: Rosenlund Milla , Kinnunen Ulla-Mari , Saranto Kaija
Published: March 2023

Background

The development of digital health services reflects not only the technical development of services but also a change in attitude and the way of thinking. It has become a cornerstone for engaging and activating patients and citizens in health management while living at home. Digital health services are also aimed at enhancing the efficiency and quality of services, while simultaneously providing services more cost-effectively. In 2020, the COVID-19 pandemic accelerated worldwide the development and use of digital services in response to requirements for social distancing and other regulations.

Objective

The aim of this review is to identify and summarize how digital health services are being used among patients and citizens while living at home.

Methods

The Joanna Briggs Institute (JBI) methodology for scoping reviews was used as guidance. A search conducted in 3 databases (CINAHL, PubMed, Scopus) resulted in 419 papers. The reporting was conducted by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for scoping review (PRISMA-ScR), and the analysis of the included papers was performed using a framework consisting of 5 clusters describing the use of digital health services. After screening and excluding papers that did not match the inclusion criteria, 88 (21%) papers from 2010 to 2022 were included in the final analysis.

Results

Results indicated that digital health services are used in different situations and among different kinds of populations. In most studies, digital health services were used in the form of video visits or consultations. The telephone was also used regularly for consultations. Other services, such as remote monitoring and transmitting of recorded information and the use the of internet or portals for searching information, were observed as well. Alerts, emergency systems, and reminders were observed to offer possibilities of use, for example, among older people. The digital health services also showed to have potential for use in patient education.

Conclusions

The development of digital services reflects a shift toward the provision of care regardless of time and place. It also reflects a shift toward emphasis on patient-centered care, meaning activating and engaging patients in their own care as they use digital services for various health-related purposes. Despite the development of digital services, many challenges (eg, adequate infrastructure) still prevail worldwide.
Patient and Provider Perspectives on Symptom Monitoring During Outpatient Chemotherapy: Interview Study
Authors: Chen Leeann , Bartel Christianna , Cai Xinlu , Cheng Yanghuidi , Perer Adam , McClaine Sean , Kairis Elizabeth , Durica Krina , Huang Weiyu , Low Carissa A
Published: March 2023

Background

Fluctuating symptoms and side effects are common during outpatient cancer treatment, and approaches to monitoring symptoms vary widely across providers, patients, and clinical settings. To design a remote symptom monitoring system that patients and providers find to be useful, it may be helpful to understand current clinical approaches to monitoring and managing chemotherapy-related symptoms among patients and providers and assess how more frequent and systematic assessment and sharing of data could improve patient and provider experiences.

Objective

The goals of this study were to learn about patient and provider perspectives on monitoring symptoms during chemotherapy, understand barriers and challenges to effective symptom monitoring at one institution, and explore the potential value of remote symptom monitoring between provider visits.

Methods

A total of 15 patients who were currently undergoing or had recently completed chemotherapy and 7 oncology providers participated in semistructured interviews. Interviews were transcribed and coded using an iterative thematic analysis approach. The study was conducted at a National Cancer Institute–Designated Comprehensive Cancer Center.

Results

Four main themes were discussed by patients and providers: (1) asynchronous nature of current methods for tracking and managing symptoms, (2) variability in reported symptoms due to patient factors, (3) limitations of existing communication channels, and (4) potential value of real-time remote symptom monitoring during chemotherapy. Current asynchronous methods and existing communication channels resulted in a disconnect between when symptoms are most severe and when conversations about symptoms happen, a situation further complicated by memory impairments during chemotherapy. Patients and providers both highlighted improvements in patient-provider communication as a potential benefit of remote real-time symptom monitoring. Providers also emphasized the value of temporal data regarding when symptoms first emerge and how they progress over time, as well as the potential value of concurrent activity or other data about daily activities and functioning. Patients noted that symptom monitoring could result in better preparation for subsequent treatment cycles.

Conclusions

Both patients and providers highlighted significant challenges of asynchronous, patient-initiated, phone-dependent symptom monitoring and management. Oncology patients and providers reported that more routine remote monitoring of symptoms between visits could improve patient-provider communication, prepare patients for subsequent chemotherapy cycles, and facilitate provider insight and clinical decision-making with regard to symptom management.
Bibliometric and visualization analysis of immunogenic cell death from 2012 to 2022 (Preprint)
Authors: Zhang Chuanhe , Tan Yao , Wang Jing , Huang Jianguo , Chen Tianyu , Zhang Siyu , Liu Ziling , Zou Chang , Qin Bo
Published: March 2023

BACKGROUND

In recent years, immunogenic cell death (ICD) has been intensively studied. ICD is a form of regulated cell death (RCD) that is sufficient to trigger an adaptive immunological response specific for antigens produced on dying cells.

OBJECTIVE

This study aimed to analyze the foundation and frontiers of ICD research through bibliometric analysis.

METHODS

Articles and reviews on ICD from 2012 to 2022 were obtained from the Web of Science Core Collection and Pubmed. Countries, institutions, authors, journals, references, and keywords were analyzed and visualized using VOSviewer and CiteSpace.

RESULTS

In total, 2986 publications were included in the study. The global literature on ICD research has increased from 2012 to 2022. China and the United States contributed the greatest number of articles. Among the top 10 institutions, 50% were in France. The Chinese Academy of Sciences was the most productive institution. Kroemer G, Zitvogel L, Kepp O, and Galluzzi L were the most productive and co-cited authors. Oncoimmunology (n = 116), Frontiers in Immunology (n = 95), and Cancers (n = 92) published the most papers on ICD. The analysis of keywords found that current ICD-related research focuses on “PD-L1”, “cancer immunotherapy”, “tumor immune microenvironment”, and “nanoparticles”.

CONCLUSIONS

ICD research has increased over the years, and future cooperation and interaction between countries and institutions must be expanded. Current ICD research focuses mostly on its mechanism molecules, the crosstalk between different forms of RCD, and its involvement in illnesses. The research on ICD in cancer and the new cancer therapy related to ICD may be future research hotspots.
Distribution of a Remote Medical Exam Device Associated with an Increase in Telehealth Use (Preprint)
Authors: Oakes Allison , Civelek Yasin , Robinson Michael , Chi Winnie
Published: March 2023

UNSTRUCTURED

Due to cost and convenience, healthcare delivery is moving from traditional care settings (e.g., physician offices, emergency departments) to quick-care retail sites. In addition, the COVID-19 pandemic quickly accelerated the use of telehealth. By providing a means for patients to receive healthcare from anywhere and at any time, telehealth platforms significantly expand patient access to medical care. However, the impact of virtual care on visit quality is less certain.
A growing topic of interest, digital health technologies may have the potential to improve aspects of virtual care. The primary objective of this study was to evaluate the impact of the FDA-approved remote monitoring device on healthcare use and spending. This evaluation suggests the use of remote devices can be used to increase uptake of telehealth, without increasing costs
Translation Strategies for Conceptual Metaphors in Financial Discourse—Taking The Economist as An Example
Authors: Qiu Xinxin
Published: March 2023

Cognitive linguistics studies conceptual metaphor as a cognitive approach, which is essentially a mapping of one conceptual domain to another. Depending on the originating domain, conceptual metaphors can be classified into structural metaphors, orientation metaphors and ontological metaphors. In this paper, we analyze the hidden cognitive bases and tendencies behind these three types of metaphors by showing their use in The Economist, and explore the translation strategies of conceptual metaphors in financial discourse.
Does Blended Learning Approach Affect Madrasa Students English Writing Errors? A Comparative Study
Authors: Usama Mohammad
Published: March 2023

Previous studies analyzed errors in English as a second language writing in school or university; no work has been conducted on Indian Madrasa (Islamic institution) students’ errors in English writing. The current study analyzes Madrasa students’ English writing errors. The students were grouped into an experimental group (EG) and control group (CG) and engaged for twenty-eight days, where only EG learners received blended learning (BL) treatment. The investigation used a pre-and post-test purposive design across all the groups. The errors were spotted from their write-ups belonging to morphological, syntactical, and orthographical categories. Next, errors were analyzed both quantitatively and qualitatively. Though the results revealed that both groups committed errors in all seven categories: morphological (article and preposition), syntactical (tense and word order), and orthographic (capitalization, spelling, and punctuation) types, EG’s errors were fewer than CG’s. This implies that BL can lead to effective remedial writing in Madrasa classrooms. In addition, EG’s pre-test scores were also greater than post-test scores, which has implications for adopting BL at different Madaris in India.
Enumeration of spanning trees in prisms of some graphs
Authors: Zeen El Deen Mohamed R.
Published: March 2023

In graph theory, a prism over a graph G is the cartesian product of the graph G with P₂. The purpose of this work is to investigate the complexity of the prisms of some path and cycle-related graphs. In particular, we obtain simpler and more explicit formulas for the complexity of a special class of prisms of path-related graphs: fan graph, ladder graph, the composition Pn[P₂] graph, and book graph. Moreover, we obtain straightforward formulas for the complexity of a special class of prisms of cycle-related graphs: wheel graph, gear graph, prism graph, n−crossed prism graph, mirror graph M(Cn) of even cycle Cn, twisted prism, total graph T(Cn) of the cycle Cn, the friendship graph, the flower graph, and planner sunflower graph. These closed formulas are deduced using some basic properties of block matrix, recurrence relation, eigenvalues of circulant matrices, and orthogonal polynomials.
A theoretical approach on intuitionistic Fuzzy Hausdorff space
Authors: Sivaraman Geetha , V. J. Jasmy
Published: March 2023

The object of this paper is to introduce a new definition for intuitionistic fuzzy Hausdorff space (IFHS). We investigate some of its characterizations and discuss it with some necessary counter examples. In addition, we compared the new notion with the existing notions. Finally we point out the significance of Hausdorffness in digital image processing.
Mixed Fuzzy topological space its Hausdorff properties and base
Authors: Chetri Hari Prasad , Ray Gautam Chandra
Published: March 2023

In this article, mixed fuzzy topology and its topological properties have been studied. Mixed fuzzy topology is defined with the help of quasi-coincidence and closure of a fuzzy set in one of the fuzzy topologies. Thus, a new fuzzy topology is generated from the given two fuzzy topologies. This new fuzzy topology may or may not contain the topological properties of the parent topologies. This study identifies some topological properties that are carried to the mixed fuzzy topology from the given parent fuzzy topologies and some other properties which are not carried to the mixed fuzzy topology. Here a base for mixed fuzzy topology from the bases of the given parent topologies is constructed. Considering the regularity of one of the parent topologies mixed fuzzy topology is investigated. Hausdorff’s properties of mixed fuzzy topological spaces are also discussed. It is now of general interest to know which properties are carried to the mixed topology and which are not. A few of these are being tried to answer here in this paper.
PMSG Wind Energy Conversion Systems ZSI
Authors: Subahan G. M. , Reddy G. Surendra , Reddy Y. Veera , Reddy G. Sudheer , Vishnu G. , Srinivasulu M.
Published: March 2023

Abstract: Recently Permanent Magnet Synchronous Generator are mostly used in the Wind Energy Conversion System applications This work is clearly deal with the study of Wind Energy Conversion System WECS by way of Permanent Magnet Synchronous Generator PMSG with Z Source Inverters. The PMSGs and wind turbines are gradually entered in the field of power generation huge wind farms are used at constant voltage and frequency to increase capacity power supply Particularly Permanent Magnet Synchronous Generators is used in this machinery due to special characteristics such as low weight volume and high. PMSG never required the power supply at the starting time of power production PMSGs run at synchronous speed. These type of inverter are classified has Z-Source Inverter ZSI, Quasi Z Source Inverter QZSI, Trans Z Source Trans ZSI and Cascaded Multi Cell Z Source Inverter CMCTZSI etc. This inverter is operated such as shoot through state and on shoot through state previously to convert DC supply to AC supply where the DC supply side have been boosted up to required AC supply level are executed. The above mention shoot through state is not applicable to implementing in the conventional Voltage Source Inverter VSI and Current Source Inverter CSI. The PMSG and types of Z Source inverter systems are simulated in MATLAB Simulation platform.
Execution of IoT System using Blockchain with Authentication and Data Protection
Authors: Rubika M , Senthilvelan Prof. S. , Sneka N.
Published: March 2023

Abstract: Blockchain allows users and data providers to ensure authentication, authorization and data validity with proper multi-key exchange authentication for user identity and hash key for Blockchain so that the data is not just stored but also validated each time the user access. In this paper, we apply Zero Knowledge proof to a Strong rooms using RFID Card reader and Camera module IoT systems to prove that a prover without disclosing information such as public key enhances the anonymity of Blockchain
Chest X-ray Analysis Using Deep Learning Algorithm
Authors: Tembhare Prof. Puneshkumar U. , Tonge Prathamesh , Verulkar Bhavesh , Thakre Sankalp , Balpande Shreya , Parshive Pranjali
Published: March 2023

Abstract: Automatic recognition of key chest X-ray results to help radiologists with clinical workflow tasks like time-sensitive triage, pneumothorax (CXR) is crucial Case screening and unanticipated discoveries. Deep learning (DL) models have become a promising prediction technique with near-human accuracy, but usually suffer from a lack of explain ability. Medical professionals can treat and diagnose illnesses more precisely thanks to automated picture segmentation and feature analysis. Because diverse equipment provides images with varying image quality, automatic segmentation of medical images is difficult. According to one research,15% of 104 patients with pleural effusion died within 30 days. In this paper, we propose a model for automatic diagnosis of 14 different diseases based on chest radiographs using machine learning algorithms. Chest X-rays offer a non-invasive (perhaps bedside) method for tracking the course of illness. A severity score prediction model for COVID-19 pneumonia on chest radiography is presented in this study.
A Survey Paper on Hard Disk Failure Prediction Using Machine Learning
Authors: Shaikh Abdulmuiz , Dubey Harsh , Bajhal Shreyash , Bhadoriya Anuj
Published: March 2023

Abstract: Failure of Hard Disk is a term most companies and people, fear about. People get concerned regarding data loss. Therefore, predicting the failure of the HDD is an important and to ensure the storage security of the data center. There exist a system named, S.M.A.R.T. (Self-Monitoring, Analysis and Reporting Technology) in hard disk tools or bios tools which stands for Self-Monitoring, Analysis and Reporting Technology. Our project will be predicting the failure of hard drive whether it will fail or not. This prediction will be based on Machine Learning algorithm. S.M.A.R.T. values of hard disk will be extracted from external tool.
Laptop Performance Prediction
Authors: T Adithya , Albinaa Dr. T. A.
Published: March 2023

Abstract: The “LAPTOP PERFORMANCE PREDICTION” is an important metric used to predict the performance of laptops Laptop manufacturers spend a lot of time, resources, and money designing new systems and newer configurations. Their ability to reduce costs, charge competitive prices, and gain market share depends on how well these systems perform. In this work, concentrate on the system and architectural design processes for parallel computers and develop methods to expedite them. The methodology relies on extracting the performance levels of a small fraction of the machines in the design space and using this information to develop machine learning models to predict the performance of any machine in the whole design space. Laptop performance prediction is useful to accelerate the design space exploration significantly and aid in reducing the corresponding research/development cost and time-to-market.