bluuebunny/crossref_metadata_2025 huggingface dataset:
Glucocorticoid-induced Changes in the Transcriptional Activity of Genes of the Innate and Adaptive Immune System in the Blood of Patients with Acute Urticaria
Authors: Petruk Alina , Kamyshna Iryna , Shkilna Mariia , Kamyshnyi Aleksandr
Published: November 2021

Background: A number of the main effects of glucocorticoids (GCs) are their direct action on T cells, mainly through the transcriptional regulation: elevated expression of immune-regulatory proteins, inhibitory receptors, and reduced expression of pro-inflammatory cytokines, co-stimulatory molecules, and cell cycle mediators. But controversies arise due to the clinical effectiveness of GCs in the treatment of acute urticaria. Methods: In our research, we applied a pathway-specific PCR array (Human Innate & Adaptive Immune Responses RT2 Profiler PCR Array, QIAGEN, Germany) to detect and verify innate & adaptive immune responses pathway-focused genes expression in the blood of patients with acute urticaria who received treatment with glucocorticoids in addition to standard therapy. Results: Adding glucocorticoids to standard therapy did not notably affect the nature of the clinical presentation of acute urticaria, which was assessed according to the UAS scale (urticaria activity score). Analysis of the transcriptional profile of peripheral blood mononuclear cells in patients with acute urticaria against the background of glucocorticoid therapy showed the induction expression of the FOXP3 and IL10 genes against the background of repression of the transcriptional activity of the genes for chemokines and cytokines CCL5, CXCL8, IFNG, IL2, IL5, IL17A, IL1B, and TNF. Glucocorticoid-induced changes in the transcriptome also manifested by pronounced repression in genes of CD40 and CD80 (B7-1) co-stimulatory molecules, transcriptional regulators of Th1-cells differentiation - TBX21 and STAT1, Th17 cells - RORC, NLRP3-inflammasome genes, and the transcription factor NFKB1 compared with the control group. Conclusions: Adding glucocorticoids to the standard therapy of acute urticaria has a pronounced immunosuppressive potential at the transcriptome level of immune response genes in the blood; however, it does not have any noticeable clinical effect.
Jordan matrix algebras defined by generators and relations
Authors: Luo Yingyu ,   College of Mathematics, Changchun Normal University, Changchun 130032, China, Wang Yu , Gu Junjie , Wang Huihui ,   Department of Mathematics, Shanghai Normal University, Shanghai 200234, China
Published: November 2021

In the present paper we describe Jordan matrix algebras over a field by generators and relations. We prove that the minimun number of generators of some special Jordan matrix algebras over a field is $ 2 $.
Post-quantum Simpson's type inequalities for coordinated convex functions
Authors: You Xue-Xiao ,   School of Mathematics and Statistics, Hubei Normal University, Huangshi, Hubei 435002, China, Ali Muhammad Aamir , Murtaza Ghulam , Chasreechai Saowaluck , Ntouyas Sotiris K. , Sitthiwirattham Thanin ,   Jiangsu Key Laboratory for NSLSCS, School of Mathematical Sciences, Nanjing Normal University, Nanjing, 210023, China,   Department of Mathematics, University of Management and Technology, Lahore, Pakistan,   Department of Mathematics, Faculty of Applied Science, King Mongkut's University of Technology North Bangkok, Bangkok, 10800, Thailand,   Department of Mathematics, University of Ioannina, 451 10 Ioannina, Greece; Nonlinear Analysis and Applied Mathematics (NAAM)-Research Group, Department of Mathematics, Faculty of Science, King Abdulaziz University, P.O. Box 80203, Jeddah 21589, Saudi Arabia,   Mathematics Department, Faculty of Science and Technology, Suan Dusit University, Bangkok, 10300, Thailand
Published: November 2021

In this paper, we prove some new Simpson's type inequalities for partial $ (p, q) $-differentiable convex functions of two variables in the context of $ (p, q) $-calculus. We also show that the findings in this paper are generalizations of comparable findings in the literature.
Nursing staff fatigue and burnout during the COVID-19 pandemic in Greece
Authors: Sikaras Christos ,   Nursing Department, Sotiria Thoracic Diseases Hospital of Athens, 11527 Athens, Greece, Ilias Ioannis , Tselebis Athanasios , Pachi Argyro , Zyga Sofia , Tsironi Maria , Gil Andrea Paola Rojas , Panagiotou Aspasia ,   Department of Endocrinology, “Elena Venizelou” Hospital, 11521 Athens, Greece,   Psychiatric Department, Sotiria Thoracic Diseases Hospital of Athens, 11527 Athens, Greece,   Department of Nursing, University of Peloponnese, 22100 Tripoli, Greece
Published: November 2021

Introduction

The coronavirus pandemic (COVID-19) is an unprecedented global health crisis with emotional and physical impact on health care workers.

Objective

The purpose of this study was to investigate the levels of fatigue and burnout in nursing staff during the pandemic.

Methods

The present study involved nursing staff from hospitals in Greece in February 2021, who completed the Fatigue (FAS) and Burnout (CBI) questionnaires. Gender, age, years of work experience, workplace (COVID-19 or non-COVID-19 wards) and SARS-CoV-2 infection status were recorded.

Results

The sample included 593 women and 108 men, with a mean age ± SD: 42.9 ± 9.9 years and 18.14 ± 10.8 years work experience. Slightly more than half, (367, 52.4%) worked in COVID-19 departments. Fifty-six (8%) tested positive for SARS-CoV-2 and 14 of them needed to be treated. The mean ± SD FAS and CBI scores were 25.6 ± 7.4 and 46.9 ± 18.8, respectively (67.9% and 42.9% had scores suggestive of fatigue and burnout, respectively). Women showed higher values in both scales (p < 0.01). Subjects working in COVID-19 wards scored significantly higher on both the FAS and CBI scales; they were also younger and with less work experience (p < 0.01). Staff treated for COVID-19 scored higher on the burnout scale (p < 0.01) than the uninfected staff. Fatigue showed a strong positive correlation with burnout (p < 0.01, r = 0.70). Stepwise multiple regression showed that the variation of fatigue was explained by 47.0% and 6.1% by the scores on the subscales of personal and work-related burnout, respectively.

Conclusion

In conclusion, high rates of fatigue and burnout were found in the studied population. Nurses working with COVID-19 patients had higher rates of fatigue and burnout compared to those working elsewhere. There was a strong positive correlation (r = 0.70) between burnout and fatigue. Particular attention should be paid to staff who became ill and need to be treated.
El paisaje en el proyecto turístico obrero de las Ciudades de Vacaciones de Educación y Descanso
Authors: Carcelén González Ricardo
Published: November 2021

La Obra Sindical Educación y Descanso promovió en los años 50 un proyecto turístico para la clase obrera de nuestro país con la construcción de tres ciudades de vacaciones en Tarragona, Marbella y Perlora, que mostraron actitudes encaminadas a la preservación y puesta en valor del paisaje natural, desde el propio trazado de los conjuntos hasta el diseño de sus arquitecturas. En este trabajo se analizan dichas actitudes desde un punto de vista tanto cualitativo como cuantitativo, arrojando datos objetivos que reflejan la relación del referido proyecto turístico obrero con el paisaje. Con la llegada de los años 60 y de los grandes planes de ordenación turística de promoción privada, la Obra Sindical se vio obligada a introducir algunas variaciones sobre su modelo vacacional -en su proyecto para Punta Umbría, Huelva- que, como se concluye en este trabajo, conducirá a una manifiesta transgresión de su relación original con el paisaje.
Protocolo para el uso de vehículos aéreos no tripulados en la inspección de edificios agroindustriales
Authors: Gómez Javier , Tascón Alberto
Published: November 2021

Los vehículos aéreos no tripulados, comúnmente denominados drones, son una tecnología con muchas aplicaciones potenciales en la construcción. Entre las más evidentes está la inspección de edificios durante las fases de construcción y puesta en servicio o como parte de su programa de mantenimiento. Los drones también pueden combinarse con la termografía para realizar evaluaciones energéticas. Este trabajo presenta un protocolo para la inspección de edificios agroindustriales formado por 5 fases, cada una constituida por diversas tareas. El protocolo se desarrolló a partir de experiencias previas reportadas en otros sectores, regulaciones existentes y la propia experiencia de los autores. Además, se ha validado mediante su aplicación a un caso real: una nave climatizada para crianza de vino de 7.200 m2 recién construida. La inspección proporcionó información gráfica de utilidad, tanto visible como infrarroja, y se detectaron dificultades, aspectos a considerar y precauciones para el uso de estas tecnologías.
La participación del clero secular en las congregaciones de los pueblos de indios: el caso de Atlacomulco y San Juan de los Jarros 1592-1604
Authors: Santiago Cortez Felipe
Published: November 2021

El objetivo de este artículo es analizar la participación del clero secular en las congregaciones de los pueblos de indios. Mi contribución al debate sobre las congregaciones es estudiar el papel de los curas como actores sociales complejos que no se circunscribe a escenarios propios de su actividad religiosa, sino que actúan como verdaderos negociadores, intermediarios y agentes políticos de los pueblos. Para ello, analizo el caso de Juan González de Urbina, cura de Atlacomulco, personaje principal del documento inédito de la congregación de Atlacomulco.
Covid-19 em Portugal : A liberdade religiosa na era secular
Authors: Moniz Jorge Botelho
Published: November 2021

Este trabalho analisa o impacto das restrições à liberdade religiosa, provocadas pelo estado de emergência sanitária, ligado à pandemia da covid-19, durante o primeiro período de confinamento em Portugal. Ao partir do marco teórico da era secular e secularidade, esta investigação permite interpretar, através de uma análise qualitativa, hipotético-dedutiva, o lugar da religião em sociedades marcadas por culturas de secularidade. Conclui-se que a normalização da subordinação de valores e práticas religiosas aos da esfera política, evidenciada pela hierarquização de atividades essenciais e não-essenciais, e a sua promoção através da autossecularidade esvaziam a presença da religião no espaço público e ajudam no avanço de uma cultura de secularidade.
Stereotypic Expansion of T Regulatory and Th17 Cells during Infancy Is Disrupted by HIV Exposure and Gut Epithelial Damage
Authors: Dzanibe Sonwabile , Lennard Katie , Kiravu Agano , Seabrook Melanie S S , Alinde Berenice , Holmes Susan P , Blish Catherine A , Jaspan Heather B , Gray Clive M
Published: November 2021

Few studies have investigated immune cell ontogeny throughout the neonatal and early pediatric period, when there is often increased vulnerability to infections. In this study, we evaluated the dynamics of two critical T cell populations, T regulatory (Treg) cells and Th17 cells, over the first 36 wk of human life. First, we observed distinct CD4+ T cells phenotypes between cord blood and peripheral blood, collected within 12 h of birth, showing that cord blood is not a surrogate for newborn blood. Second, both Treg and Th17 cells expanded in a synchronous fashion over 36 wk of life. However, comparing infants exposed to HIV in utero, but remaining uninfected, with HIV-unexposed uninfected control infants, there was a lower frequency of peripheral blood Treg cells at birth, resulting in a delayed expansion, and then declining again at 36 wk. Focusing on birth events, we found that Treg cells coexpressing CCR4 and α4β7 inversely correlated with plasma concentrations of CCL17 (the ligand for CCR4) and intestinal fatty acid binding protein, IL-7, and CCL20. This was in contrast with Th17 cells, which showed a positive association with these plasma analytes. Thus, despite the stereotypic expansion of both cell subsets over the first few months of life, there was a disruption in the balance of Th17 to Treg cells at birth likely being a result of gut damage and homing of newborn Treg cells from the blood circulation to the gut.
CD8+ T Cells Expressing an HLA-DR1 Chimeric Antigen Receptor Target Autoimmune CD4+ T Cells in an Antigen-Specific Manner and Inhibit the Development of Autoimmune Arthritis
Authors: Whittington Karen B , Prislovsky Amanda , Beaty Jacob , Albritton Lorraine , Radic Marko , Rosloniec Edward F
Published: November 2021

Ag-specific immunotherapy is a long-term goal for the treatment of autoimmune diseases; however developing a means of therapeutically targeting autoimmune T cells in an Ag-specific manner has been difficult. Through the engineering of an HLA-DR1 chimeric Ag receptor (CAR), we have produced CD8+ CAR T cells that target CD4+ T cells in an Ag-specific manner and tested their ability to inhibit the development of autoimmune arthritis in a mouse model. The DR1 CAR molecule was engineered to contain CD3ζ activation and CD28 signaling domains and a covalently linked autoantigenic peptide from type II collagen (CII; DR1-CII) to provide specificity for targeting the autoimmune T cells. Stimulation of the DR1-CII CAR T cells by an anti-DR Ab induced cytokine production, indicating that the DR1-CAR functions as a chimeric molecule. In vitro CTL assays using cloned CD4+ T cells as target cells demonstrated that the DR1-CII CAR T cells efficiently recognize and kill CD4+ T cells that are specific for the CII autoantigen. The CTL function was highly specific, as no killing was observed using DR1-restricted CD4+ T cells that recognize other Ags. When B6.DR1 mice, in which autoimmune arthritis had been induced, were treated with the DR1-CII CAR T cells, the CII-specific autoimmune CD4+ T cell response was significantly decreased, autoantibody production was suppressed, and the incidence and severity of the autoimmune arthritis was diminished. These data demonstrate that HLA-DR CAR T cells have the potential to provide a highly specific therapeutic approach for the treatment of autoimmune disease.
Effect of the Monthly Injectable Combined Contraceptives versus Oral Contraceptive Pills on Mood
Authors: Khafagy Ghada M. , Shalaby Hebatallah L. , Saad Nagwa E. , Hasan Marwa D.
Published: November 2021

Background: Contraceptive agents are widely used by women of reproductive age, and resulting depression is the most common side effect of this usage. This study aimed to study the effect of monthly injectable combined contraceptives versus that of combined oral contraceptive pills (COC) on patients’ mood.Methods: A prospective cohort study was conducted on 124 females aged 18–45 years attending the Kom-Ashfeen Family Medicine Unit, El-Kalyubia, Egypt. Participants were divided into three groups according to their choice: group A included 44 participants who received monthly combined injectable contraceptives (CIC); group B included 40 participants who took COC; and group C included 40 participants who used the copper intrauterine device (IUD). The Patient Health Questionnaire-9 (PHQ-9) score was assessed at the beginning of the study and after 6 months of follow-up.Results: After 6 months of follow-up, there were mild but statistically significant increases in the PHQ-9 score in groups A and B, with group A (CIC users) showing the highest increase. Approximately 34.1%, 27.5%, and 15% of CIC, COC, and IUD users, respectively, moved from the non-depression stage to mild depression after 6 months; this change was statistically significant in groups A and B only.Conclusion: Monthly injectable combined contraceptives and oral contraceptive pills were associated with an increased risk of developing mild depression; this risk was higher in users of CICs, although the difference was not statistically significant. Thus, it is crucial to counsel patients about this possible risk and to follow them up. However, further studies are required to confirm our results.
Defining Essential Topics and Procedures for Korean Family Medicine Residency Training
Authors: Song Youhyun , Shin Jinyoung , Kim Yonghwan , Shim Jae-Yong
Published: November 2021

Background: This study aims to create a comprehensive list of essential topics and procedural skills for family medicine residency training in Korea.Methods: Three e-mailed surveys were conducted. The first and second surveys were sent to all board-certified family physicians in the Korean Academy of Family Medicine (KAFM) database via e-mail. Participants were asked to rate each of the topics (117 in survey 1, 36 in survey 2) and procedures (65 in survey 1, 19 in survey 2) based on how necessary it was to teach it and personal experience of utilizing it in clinical practice. Agreement rates of the responses were calculated and then sent to the 32 KAFM board members in survey 3. Opinions on potential cut-off points to divide the items into three categories and the minimum achievement requirements needed to graduate for each category were solicited.Results: Of 6,588 physicians, 256 responded to the first survey (3.89% response rate), 209 out of 6,669 to the second survey (3.13%), and 100% responded to the third survey. The final list included 153 topics and 81 procedures, which were organized into three categories: mandatory, recommended, and optional (112/38/3, 27/33/21). For each category of topics and procedures, the minimum requirement for 3-year residency training was set at 90%/60%/30% and 80%/60%/30%, respectively.Conclusion: This national survey was the first investigation to define essential topics and procedures for residency training in Korean family medicine. The lists obtained represent the opinions of Korean family physicians and are expected to aid in the improvement of family medicine training programs in the new competency-based curriculum.
Changes in Patterns of Physical Activity and Risk of Heart Failure in Newly Diagnosed Diabetes Mellitus Patients
Authors: Jung Inha , Kwon Hyemi , Park Se Eun , Han Kyung-Do , Park Yong-Gyu , Rhee Eun-Jung , Lee Won-Young
Published: November 2021

Background: Exercise is recommended for type 2 diabetes mellitus (T2DM) patients to prevent cardiovascular disease. However, the effects of physical activity (PA) for reducing the risk of heart failure (HF) has yet to be elucidated. We aimed to assess the effect of changes in patterns of PA on incident HF, especially in newly diagnosed diabetic patients.Methods: We examined health examination data and claims records of 294,528 participants from the Korean National Health Insurance Service who underwent health examinations between 2009 and 2012 and were newly diagnosed with T2DM. Participants were classified into the four groups according to changes in PA between before and after the diagnosis of T2DM: continuously inactive, inactive to active, active to inactive, and continuously active. The development of HF was analyzed until 2017.Results: As compared with those who were continuously inactive, those who became physically active after diagnosis showed a reduced risk for HF (adjusted hazard ratio [aHR], 0.79; 95% confidence interval [CI], 0.66 to 0.93). Those who were continuously active had the lowest risk for HF (aHR, 0.77; 95% CI, 0.62 to 0.96). As compared with those who were inactive, those who exercised regularly, either performing vigorous or moderate PA, had a lower HF risk (aHR, 0.79; 95% CI, 0.69 to 0.91).Conclusion: Among individuals with newly diagnosed T2DM, the risk of HF was reduced in those with higher levels of PA after diagnosis was made. Our results suggest either increasing or maintaining the frequency of PA after the diagnosis of T2DM may lower the risk of HF.
Influence of Motivational Design Techniques on Use and Acceptance of Self-Management Health Systems in Older Adults
Authors: D’Haeseleer Ine , Schoofs Jamie , Schutters Kim , Schreurs Dominique , Vanden Abeele Vero
Published: November 2021

INTRODUCTION: Self-Management Health Systems (SMHS) are envisioned to support older adults and contribute to ageing in place. To promote the use and acceptance of SMHS, designers may resort to using motivational design techniques (MDT).OBJECTIVES: This paper investigates how and which older adults prefer MDT in SMHS and whether these preferences are mediated by either motivation for health management (MHM) or mobile device proficiency (MDP).METHODS: Based on a user evaluation with 45 older adults (mean age=84, SD=6.75), 32 MDT, MHM, and MDP were polled through questionnaires and informal interviews.RESULTS: Findings showed that most techniques were welcomed, but also that scores vary widely, reflecting heterogeneity in the population and calling for caution in its implementation. These findings are then translated into implications for design.CONCLUSION: Overall, older adults welcome MDT in SMHS. However, MDT are no panacea; tailoring MDT to users’ needs is therefore crucial.
Graphics - Based Service Information
Authors:   Graphics Based Service Information Committee
Published: November 2021

This Digital Annex (DA) contains the current, full-PDF version
of J2892,
Graphic-Based Service Information, and all of the 143
referenced graphical symbols. Each of the symbols is presented in
two file formats, Adobe Illustrator (vector art) and Portable
Network Graphic (raster image), and can be used by purchasers
according to the terms of the included license agreement.
Bioaccumulation of auto-mechanic wastes in the tissues of Pellonula Afzeliusi (Johnels, 1954) collected from Agba stream Ilorin, Kwara State, Nigeria
Authors: Adeyemi-Ale O. A. , Oladipo S. O. , Abdulkareem S. I.
Published: November 2021

Hydrocarbons and heavy metals (HM) present in automobile wastes get into water bodies close to automobile mechanic villages. They deteriorate the physico-chemical qualities of such water bodies and exert toxic effects on fish and other aquatic fauna. They also pose risks to humans that consume fish from streams near such automechanic villages. There is paucity of information on the HM contents of Agba stream, Ilorin and no information on the bioaccumulation of HM in the tissues of Pellonula afzeliusi is currently available. The purpose of this study was to assess the physico-chemical qualities of water and bioaccumulation of HM in the tissues of Pellonula afzeliusi fish collected from Agba stream, Ilorin, Kwara State, Nigeria. Water and samples of Pellonula afzeliusi were collected from the upstream (station A), midstream (station B) of Agba stream located close to an auto-mechanic village and Oyun dam (control site, station C) located within the University of Ilorin. Standard methods were used to analyse oil and grease (OG), total petroleum hydrocarbon (TPH) and HM in water samples. The concentrations of TPH and HM were analysed in the skin, bone, muscle, gills, gastrointestinal tract, liver and kidney of the fish. The order of water HM concentrations indicated Zn > Cd > Ba> Fe > Pb at station A; Cd > Zn > Fe > Ba > Pb at station B, and Zn > Ba > Pb > Fe >Cd at station C. TPH and HM bioaccumulated in the tissues of fish while lead was not detected in all tissues from station C. Bioaccumulation factor varied with the highest values  t station C. The result of this study indicated heavy pollution burden in station B with lower pollution burden in station C (the control site). These call for attention of government in ensuring ecological restoration and prevention of further discharge of automobile wastes into the stream.

Keywords: Automobile wastes, Heavy metals, Hydrocarbons, Bioaccumulation, Pellonula afzeliusi
Metagenomic tracking of microbial consortia of cassava flakes (garri)
Authors: Thomas B.T. , Efuntoye M.O. , Kolawole R.M. , Popoola O.D. , Tajudeen A.O.
Published: November 2021

The affirmation of several cross-sectional studies on the vulnerability of cassava flakes commonly called 'garri' to microbial attack has long been documented. However, longitudinal data on metagenomic tracking of microbial consortia of this important staple food are scarce. Hence, this study was aimed at tracking the microbial consortia of garri. A total of eight samples (four each from both Nigeria and Republic of Benin markets) were randomly collected aseptically using pre-sterilized aluminum pans and processed through a metagenomic approach, while both the chemical and proximate components of garri were assessed following standard techniques. The analysis of the taxonomic consortia of garri reveals the predomination of bacteria (99.82 and 99.81% for samples from Nigeria and Republic of Benin, respectively) while the remaining sequences matched with the Archae (0.07%), fungi (0.09%) and protozoa (0.09%). A large proportion of the sequences were unclassified at the phylum level (approximately 84.10 and 86.2% for Nigerian and Beninese samples, respectively). The reads of cassava flakes metagenome of both Nigeria and Republic of Benin exhibited analogous level of average GC content with sequence count of between 187773-213444 for samples from Nigeria and 157784-198763 for samples from Republic of Benin. The functional characteristics of the inhabiting metagenomes were found containing the genes encoding for adhesins, bacteriocins, resistance to antibiotics, toxic chemicals as well as toxins and superantigens. Both the chemical and the proximate compositions of the examined garri samples, though exhibited significant disparity, but without any apparent variation in the patterns of metagenomic data. Our findings however revealed bacteria as the major contaminants of these cassava food products.

Keywords; Metagenomics, Microorganisms, Cassava flakes (garri), Proximate composition
Autonomiczny charakter zadaniowego czasu pracy nauczyciela akademickiego
Authors: Lekston Mariusz
Published: November 2021

Autonomous character of task-based working time of a academic teacher

Employment relationship of a academic teacher, determined by pragmatic regulations of the higher education act, demonstrates specific characteristics in various aspects, with particular focus on the aggregate of rights and obligations. This kind of reflection makes also regulation of working time to be perceived through the prism of the characteristics of the employment relationship of a academic teacher since its particular content elements determine differences in defining the task-based working time. The mechanism of implementing the system of working time, tasks of a academic teacher, and in particular regulations connected with providing the teaching obligations are essential factors in defining the autonomous character of the task-based working time system of a academic teacher.
Obowiązek zgłoszenia umowy o dzieło do ZUS – usprawnienie systemu kontroli w świetle konstytucyjnych zasad równości, proporcjonalności i autonomii informacyjnej
Authors: Miętek Agata
Published: November 2021

Obligation to notify Social Security Agency about a specific work contract – improvement of the control system in the light of constitutional principles of equality, proportionality and information autonomy

The purpose of the paper is to analyze obligation to notify Social Security Agency about concluded specific work contracts, which was introduced as of 1 January 2021 in the social security system act. Firstly, the way in which the new obligation was introduced raises significant doubts. Under the guise of anti-crisis measures, a new obligation has been introduced in the Anti-Crisis Shield, which has little to do with its purpose. Secondly, the prima facie technical obligation also raises practical doubts, but more importantly, it prompts questions about its compliance with the constitutional principles of equality, proportionality and information autonomy. Fulfillment of the obligation results in transfer to the Social Security Agency of significant data on legal relationship that are – as a rule – indifferent from the perspective of the social security system, the scope of which is not determined by a statute, but by a sub-statutory act.
GAZİLER VE ORDUDA SOSYAL HİZMET UYGULAMALARI
Authors: PEKER Fatma , ÖZBESLER Cengiz
Published: November 2021

Terörle mücadele sürecinde malul (engelli) gazi sayısı her geçen gün artmaktadır. Ateşli silahla yaralanma, mayına basma veya bombalama gibi olaylar, silahlı kuvvet mensuplarında yaralanmalara neden olmaktadır. Silahlı kuvvet mensupları görevleri sırasında aldıkları bu yaralanmalar nedeniyle organ kaybı yaşarmakta hatta bazıları işlev kaybına uğramaları sonucu malul gazi olmaktadırlar. Görevleri nedeniyle çatışmanın içinde yer alarak doğrudan ölüm tehdidi içeren ve travmatik deneyim yaşayan ve bununla birlikte fiziksel olarak yaralanan gazilere destek sağlanması önemlidir. Yaralanma sonucu yaşanan kayıplar gaziler için risk ve tehdit içermekle birlikte pek çok gazi yeni durumlarına uyum sağlayabilmektedir. Yeni durumlarına uyum sağlamalarında sağlamlıkları, baş etme becerileri ve onlara bakım veren kişilerin desteklerinin önemli olduğunu söylemek mümkündür. Gaziler için uyum pek çok bireyin sahip olduğu kaynaklara ve bu süreçteki kayıp/kazanca yüklediği anlamlarla şekillenmektedir. Bu yazıda gazi müracaatçılar ile yaralanmanın ardından ıehabilitasyon sürecinde orduda sosyal hizmet uygulamaları ele alınacaktır. Bu derleme yazısının gazilerin kayıplarının ardından yaşadıklarını ve tepkileri anlama, uyumlarını kolaylaştırma yönünden gazilere hizmet veren ekibe ve gazilerin ailelerine yol gösterici olması beklenmektedir.
Intelligent Face Tracking for Collaborative Synchronous e-Learning using Pattern Recognition Model
Authors: Naijit Kittimasak
Published: November 2021

Intelligent Face Tracking for Collaborative Synchronous e-Learning using Pattern Recognition Model can provide high levels of interaction for distance learning initiatives. With the rapid evolution of technology, face recognition login and tracking, continuous product evaluation is necessary to ensure optimal methods and resources for connecting students, instructors, and educational content in rich, online learning communities. This article presents the analysis of online, synchronous learning solutions. Focusing on their abilities to meet technical and pedagogical needs in higher education. To make a solid comparison, the systems were examined in online classrooms with instructors, guest speakers, and students. Relative to usability, instructional needs, technical aspects and compatibility are outlined for systems.
The Selection and Training Framework for Managers in Business Innovation and Transformation Projects
Authors: Trad Antoine
Published: November 2021

The riskiest factor in transforming a traditional Business Environment (BE) into an innovative and business lean oriented BE is the role of the business and (e-)Business Transformation Manager (BTM). The basic profile of such a BTM has not been sufficiently investigated in a holistic and educational manner. The characteristics of a suitable BTM profile is the main goal of the author's selection and training framework (STF) research project; that started in the year 2010. In this research paper, the author tries to prove that the STF research methodology, design and prototype (STF_RMDP) can be applied in a "real world case"; that is in fact the final phase. This final phase is labelled the "STF research empirical model". This whole research is a part of the author's doctorate in business administration. The STF_RMDP results define the optimal BTM profile who has to cope with complex business transformation projects (BTP). These BTPs need a specific set of skills, especially for the final and the very difficult implementation phase (Trad, Kalpic, IMRA, 2013-an award winning paper). The BTP's implementation phase is the major cause of high failure rates. The BTMs' needed hands-on skills; these skills should encompass: 1) knowledge of business process and services (BPs) technologies, 2) automated real-time business environments, 3) project management, 4) knowledge integration, 5) organizational behaviour, 6) management sciences methodologies 7) enterprise application integration and other concrete BTP implementation phase know-how artefacts. Therefore the researcher recommends the technocrats profile (Fahroomand, 2004) as a "base profile" for such BTPs; that need to be complemented with crossfunctional skills (Trad, Kalpic, ITI, 2013). More specifically, this research focuses on the influence of the BTMs' hands-on business architecture experience, background and education, on managing complex BTP implementations. Where such transformations integrate avant-garde innovation, knowledge and technology. “We know that those organizations that are consistently successful at managing innovation-related changes outperform their peers in terms of growth and financial performance” (Tidd, 2006). The author has based his research model on the main fact that only around 12% of business organizations successfully manage innovation-related business transformations initiatives. Therefore, there is an important need for a dynamic and automated way of selecting and training future BTMs. BTMs who would be capable of implementing such complex BP based systems (Tidd, Bessant, 2009). Where STF_RMDP is the empirical model with which the author wants to prove that future BTMs can be selected to successfully build or reengineer various electronic and lean BE (ELBE) components. The empirical model will contain a real world prototype and surveys that will generate the need data sets the qualitative research approach.
Using Student Created Video Presentations to Build Experiential Learning in the Oral EFL Presentation Classroom
Authors: Hallemans Natalie
Published: November 2021

This qualitative study investigates the learning experiences of students in an online oral presentation class where both course delivery, presentation assignments and exams were recorded submissions uploaded to an online classroom. The objective of this study is to understand if the constructivist format of the class encouraged Kolb’s experiential learning environment and to garner any positive or negative takeaways from the experience. Data collected revealed that most students spent 1-2 hours preparing for their presentations and an additional 1-2 hours recording. The additional time spent recording alluded to the idea that recorded submissions directly impacted student motivation to improve. It was also determined that most students preferred recorded submissions because they provided an opportunity to self-reflect and correct mistakes and released them from the anxiety of performing before a live audience thus enhancing the constructivist classroom environment. While many researchers believe that oral presentations are best practiced before a live audience where the skills are normally used, in the post-COVID work environment, more people are expected to work remotely and will require online oral presentation proficiencies. Developing the skills required to deliver asynchronous presentations will make students more competitive in the job market.
Effect of Taking the Liberal Arts Course ‘Creative Thinking and Problem Solving’ on the Improvement of Creative Competencies of College Students in Science and Engineering －Focusing on Comparison Before and After COVID-19
Authors: Hur Young-Ju , Park Eun Sook
Published: November 2021

This study was conducted to derive implications on how educational activities should be organized and operated for improving creative competency in online class situations by analyzing how it has changed in classes before and after COVID-19. These classes were taken by science and engineering students who took the ‘Creative Thinking and Problem Solving’ subject operated by N University. In order to achieve the goals of this study, a pre-post test related to creative competency was administered at the beginning and end of the semester to 92 students who took the face-to-face class in the second semester of 2019, and to 120 students who took the on-line class in the second semester of 2020. The research results are as follows: Creative competency was significantly improved in the face-to-face class, but not in the online class. Looking at each sub-competency of creative competency, both the challenge spirit and problem solving ability were significantly improved in the face-to-face class. Moreover, the student’s challenge spirit ability was significantly improved in the online class, but their problem solving ability was not significantly improved. These results were similar regardless of whether the instructor changed, or if the students’ grades changed. Also, the students’ gender had no bearing on these results either. Based on these research results, as well as on our educational goals and the content of the classes, the project activities involved in the ‘Creative Thinking and Problem Solving’ subject can be used in online classes in their current form. But this study suggested that strategies for improving students' problem-solving abilities need to be supplemented. Specifically, instructors should increase communication opportunities through the parallel use of the real-time remote video system, and should guide their students to become faithful to the team-based project activities through the sub-session function of the real-time remote video system. To this end, the university may consider changing two credits of two hours into two credits of three hours, or three credits of three hours. Universities also need to operate this subject in connection with extra-activities. It is also necessary for instructors to provide a support environment where students can freely meet using the real-time remote video system, and can engage in solving problems through their own initiative.
The Historical Development and Tasks of Liberal Arts Education in Korean universities
Authors: Paek Seungsu
Published: November 2021

Korean universities have sought sustainable future-oriented liberal arts education while exploring the role of liberal arts education in the era of the 4th industrial revolution. Even so, unresolved issues arising from historical development should be overcome to take a great step toward innovating liberal arts education. The purpose of this study is to identify problems that appeared in the historical development process of liberal arts education at Korean universities and to derive overcoming tasks. The historical development of liberal arts education at Korean universities can be divided into three stages: Formation Period (1945-1972), Experimental Period (1973-2009), and Autonomous Period (2010-present). The issues that emerged in this development process have two characteristics: confusion in the identity of liberal arts education and development through government control and support. For the sustainable future of liberal arts education, it is necessary to overcome misleading perceptions that hinder the realization of the true meaning of liberal arts education and establish the identity of liberal arts education. Universities should secure autonomy from the government and more actively strengthen and innovate liberal arts education.
Impact of Social Determinants of Health on Chronic Kidney Disease: A Review of Disparities in Renal Transplantation
Authors: Lombardi Conner , Glosser Logan , Knauss Hanna , Norwood Teanya , Berry Julia , Ekwenna Obinna
Published: November 2021

Background: Striking disparity exists in the incidence and treatment of chronic kidney disease (CKD) secondary to individual social determinants of health.  Additionally, the uninsured, minority racial-ethnic groups, and Medicaid enrollees receive less nephrology care prior to being diagnosed with end-stage renal disease (ESRD). The most effective treatment for the management of kidney failure is kidney transplantation. This review addresses how social determinants of health impact the workup for patients with ESRD, with emphasis on the kidney transplant process.

 

Methods: A search was conducted via multiple online databases (MedLine, PubMed, etc.) for articles that addressed the interplay between CKD, ESRD and kidney transplantation with the social determinants of health.

 

Findings: The impact of the social determinants of health on CKD, ESRD, and the kidney transplantation process can be qualitatively and quantitatively measured using the five categories of education, health care and access, economic stability, neighborhood and built environment, and social and community context.

 

Conclusion: Social determinants of health impact outcomes in CKD, ESRD, and kidney transplantation. Public and private initiatives aimed at reducing social disparities among patients with kidney disease must include emphasis on education, health care and access, economic stability, neighborhood and built environment, and social and community context. This initiative is necessary to prevent progression to ESRD and to ensure quality care in the kidney transplantation process.
Da guerrilha ao partido: transformações políticas na trajetória da Ação Libertadora Nacional a partir do caso da Tendência Leninista
Authors: Malaguti Camacho Carlos Eduardo
Published: November 2021

Este artigo busca recuperar a trajetória da Ação Libertadora Nacional, desde sua fundação no ano de 1967 até os momentos em que a repressão atingiu severamente o grupo, nos anos de 1969 e 1970. Ao historicizar essa trajetória, será destacada a relação estabelecida entre as concepções teóricas da organização e os resultados práticos das possibilidades de ação, sempre mediadas pela insegurança e instabilidade da ação guerrilheira. Posteriormente, será analisado o documento Uma autocrítica necessária, publicado em 1971, que representa um dos primeiros momentos em que integrantes do grupo passaram a questionar a ação armada como caminho para a instauração do socialismo no Brasil. O diálogo com esse documento se mostrou profícuo para a apresentação de algumas hipóteses que podem lançar luz à novas perspectivas sobre o fenômeno da luta armada no Brasil.
Digital transformation of the educational and methodological support of the railway university
Authors: Boikov E. V. , Orlenko A. I. , Domnin S. V.
Published: November 2021

A full-fledged transformation is impossible without the use of new didactic approaches and without the creation of a qualitatively new educational and methodological support. This is due to the peculiarities of the modern student. Modern students were born and grew up in an information-saturated world and they are dominated by clip thinking, which is focused on processing information in short portions. Based on this, the problem of developing such training programs that would be aimed at independent work, based on game methods of presenting information, would take into account the psychophysiological features of perception, processing and storage of information by a modern person becomes urgent.

To solve this problem, the authors analyzed the results of cognitive psychology research, conducted a self-analysis of the experience of developing and implementing three-dimensional interactive training programs in the educational process.

The paper reveals the problems and disadvantages of traditional ways of presenting information. Examples of the implementation of interactive training applications are shown. The method of organizing a distributed distance learning system is presented.

The conducted research allowed us to outline ways to modernize educational and methodological support by using interactive applications, mobile learning, resource allocation, introduction of modern digital solutions and creation of a comfortable educational environment.
Dickens’s Consumptive Urbanity: Consumption (Tuberculosis) through the Prism of Victorian Sensibility
Authors: Boev Hristo
Published: November 2021

This article examines the correlation between consumption and tuberculosis in Dickens’s city, tracing the evolution of its representations in his novels. It compares these representations to the coverage of the disease in Victorian newspapers against criticism on tuberculosis and literature. In so doing, the article establishes Dickens as a writer divided by his scientific approach as a city life chronicler and his Victorian imagination. Since consumption and consumerism as a phenomenon appeared in the mid-19th century, the text also aims to determine the dimensions of the interaction between consuming the city and being consumed by it and how this is related to tuberculosis. The researched material includes early to mid-Dickens’s works since tubercular presence is the strongest felt and the most significant there; thus, consumption (tuberculosis) in Dickens can be considered the Janus face of early consumerism, resulting from insufficient consumption of food and proper care.
SEARCH PROCEDURE AND DATA EXTRACTION FOR META-ANALYSIS IN BIOMEDICAL RESEARCH
Authors:   Institute for Information Technologies, University of Kragujevac, Obradovic Jasmina , Jurisic Vladimir
Published: November 2021

The meta-analysis provides a unique scientific conclusion with precise statistical analysis of pooled data extracted from previously reported relevant studies. That gives a better insight into the current issue with more statistical certainty than any single study observation in biomedical research. Occasionally, meta-analyses don’t provide a precise time for each step of the search strategy. The complete meta-analysis procedure is usually time-consuming, with 6-18 months reported, but it depends on the numbers of collected articles manually reviewed by two or more researchers to prevent potential bias. The purpose of this paper was to present a part of meta-analysis research with a focus on a timeline manner for extraction procedure and suggestions for preparing the database of collected articles. PRISMA guidelines were followed, and Pub Med, Scopus, and ISI Web of Science for the search were used. EndNote reference manager v.7 and Microsoft Excel 2007 were used for base preparation. Results showed that the final reference number was 4918, and 99.88% of them were excluded. A month was necessary for the search of the electronic databases. For reading titles and abstracts and extracting the papers was needed the fourth month. A month was needed for an additional search of bibliographies of the eligible papers. Even with the dedication of the team of reviewers, it is hard to predict the exact time for conducting the meta-analysis, indeed. Our results could be applicable in planning the potential systematic reviews, with or without meta-analysis, and overcoming the obstacles in the single database preparation.
Esclerites
Authors: Nascimento Heloisa , Vieira Luis Antonio , Adán Consuelo Bueno Diniz
Published: November 2021

Esclerite corresponde a um grupo heterogêneo de doenças, caracterizado por inflamação da esclera, que pode ter como causa infecções sistêmicas ou locais, ou ainda doenças imunologicamente mediadas, síndromes mascaradas decorrentes de infecção ou neoplasia. É uma entidade dolorosa e destrutiva do olho que pode levar a dano estrutural permanente e comprometimento visual. Frequentemente afeta os tecidos circunjacentes à esclera, como episclera, úvea e córnea. Sua incidência varia de 0,08% a 4%. Não apresenta predisposição racial ou geográfica. A esclerite autoimune é a forma mais comum de esclerite. Cerca de 40% dos casos de esclerite estão associados a uma doença sistêmica (um terço dos pacientes com esclerite nodular ou difusa e dois terços dos pacientes com esclerite necrosante), principalmente artrite reumatoide. É uma doença que ainda permanece enigmática. Causada por processo autoimune (microangiopatia localizada mediada por imunocomplexo, ou reação de hipersensibilidade tipo III. O encontro de inflamação crônica granulomatosa, caracterizada por predomínio de macrófagos e linfócitos T, nos achados histopatológicos de biópsias de esclerite, sugere uma disfunção da imunidade celular ou reação de hipersensibilidade tipo IV. Apesar de se tentar demonstrar a presença de antígenos específicos associados aos vasos e ao dano do tecido escleral, ou de se reproduzir mecanismos patogênicos sugeridos em modelos animais experimentais, não se produziram alterações consistentes.