bluuebunny/crossref_metadata_2025 huggingface dataset:
Genetic Characterization and Pathological Analysis of a Novel Bacterial Pathogen, Pseudomonas tructae, in Rainbow Trout (Oncorhynchus mykiss)
Authors: Oh Woo Taek , Kim Ji Hyung , Jun Jin Woo , Giri Sib Sankar , Yun Saekil , Kim Hyoun Joong , Kim Sang Guen , Kim Sang Wha , Han Se Jin , Kwon Jun , Park Se Chang
Published: October 2019

Pseudomonas species are one of the most prevalent bacterial species globally distributed in forest soil, river water, and human or animal skin. Some species are pathogens or opportunistic pathogens in hospitalized patients, animals, and plants. Various Pseudomonas species, including Pseudomonas putida, P. plecoglossicida, P. aeruginosa, and P. fluorescens, are known fish pathogens; P. fluorescens and P. putida cause severe losses in rainbow trout farming. Therefore, we investigated and isolated the pathogen that is responsible for mortality in a rainbow trout farm in Korea. The isolated bacterium was a strain of P. tructae, which was recently classified in the P. putida group. We performed taxonomical analysis of the bacteria in our previous study. In this study, we investigated the pathogenicity and clinical symptoms of P. tructae and analyzed its genomic characteristics. The pathogenicity of the strain was tested via challenge experiments in healthy rainbow trout and histopathologic analysis of the infected fish. Genome sequence was analyzed to identify the bacterial genes that are involved in antibiotic resistance and virulence. This is the first study reporting P. tructae as an emerging pathogen that is responsible for mortality in rainbow trout fisheries and providing the genome sequence of P. tructae.
The Removal of Uranium and Thorium from Their Aqueous Solutions by 8-Hydroxyquinoline Immobilized Bentonite
Authors: A. Salah Bahaa , S. Gaber Mohamed , T. Kandil Abdel hakim
Published: October 2019

The sorption of uranium and thorium from their aqueous solutions by using 8-hydroxyquinoline modified Na-bentonite (HQ-bentonite) was investigated by the batch technique. Na-bentonite and HQ-bentonite were characterized by X-ray fluorescence (XRF), X-ray diffraction (XRD), scanning electron microscopy (SEM), and Fourier Transform Infrared (FTIR) spectroscopy. Factors that influence the sorption of uranium and thorium onto HQ-bentonite such as solution pH, contact time, initial metal ions concentration, HQ-bentonite mass, and temperature were tested. Sorption experiments were expressed by Freundlich and Langmuir isotherms and the sorption results demonstrated that the sorption of uranium and thorium onto HQ-bentonite correlated better with the Langmuir isotherm than the Freundlich isotherm. Kinetics studies showed that the sorption followed the pseudo-second-order kinetic model. Thermodynamic parameters such as ΔH°, ΔS°, and ΔG° indicated that the sorption of uranium and thorium onto HQ-bentonite was endothermic, feasible, spontaneous, and physical in nature. The maximum adsorption capacities of HQ-bentonite were calculated from the Langmuir isotherm at 303 K and were found to be 63.90 and 65.44 for U(VI) and Th(IV) metal ions, respectively.
Mung Bean Protein Supplement Improves Muscular Strength in Healthy, Underactive Vegetarian Adults
Authors: Bartholomae Eric , Incollingo April , Vizcaino Maricarmen , Wharton Christopher , Johnston Carol S.
Published: October 2019

Although vegetarian diets are considered generally protective against chronic disease, nutrient deficiencies, including protein, are possible due to low bioavailability from plant-based sources. The consequences of inadequate dietary protein include reduced lean body mass (LBM) and muscle weakness. This study examined relationships between protein intake, strength, and LBM in 37 underactive vegetarians and recorded the impact of protein supplementation (18 g/day mung bean protein) on these indices utilizing an eight-week, randomized, controlled, feeding trial. Both handgrip and knee flexor and extensor strength were measured at baseline and week eight. At baseline, LBM was significantly related to grams of protein consumed daily. LBM was also correlated to grip strength (r = 0.569, p < 0.001) and lower body strength (r = 0.763 to 0.784; p < 0.001). Twenty-five vegetarians completed the feeding trial, including 11 in the protein supplementation group (PRO) and 14 in the control group (CON). At the end of the trial, LBM and strength did not differ significantly between groups. However, the average percent change for grip, flexor, and extensor strength did differ between PRO and CON participants (+2.9 ± 7.2% and −2.6 ± 7.3% respectively, p = 0.05). Thus, there were strong associations between dietary protein, LBM, and strength in vegetarians and an indication that supplementary vegetarian protein increased strength in the absence of exercise and independent of LBM.
Quantifying Actual and Perceived Inaccuracy When Estimating the Sugar, Energy Content and Portion Size of Foods
Authors: König Laura M. , Ziesemer Katrin , Renner Britta
Published: October 2019

In order to adhere to dietary guidelines and manage health risks, consumers need to be able to estimate with some accuracy the sugar and energy content of foods. The present study compared how well participants could estimate the sugar and energy content of foods, the weight of foods, and approximate portion size (using a hand measure estimation aid). The study had three aims. First, it aimed to investigate differences in accuracy across the four measures. Second, it aimed to examine whether these differences in accuracy between estimation measures were accurately perceived by the participants. Third, it aimed to test if estimation accuracy was related to food journaling experience, body-mass index or gender. One hundred and ninety-seven participants took part in an estimation task and filled in a questionnaire. While the participants were inaccurate when using all four estimation measures, inaccuracy was most pronounced for sugar content (ds ≥ 0.39), which was consistently overestimated by between 62.1% and 98.5% of the sample. None of the other measures showed a consistent pattern of under- or overestimation. Participants’ perceived accuracy did not match their actual accuracy (rs ≤ |0.20|, ps ≥ 0.005). Actual accuracy showed only marginal covariation with food journaling experience (ts ≤ 2.01, ps ≥ 0.049, ds ≤ 0.14), body-mass index (rs ≤ |0.15|, ps ≥ 0.041) or gender (ts ≤ 3.17, ps ≥ 0.002, ds ≤ 0.46). It is particularly challenging for consumers to estimate the sugar content of food, which might have negative consequences for health and well-being. Thus, more education about sugar content and misperceptions is needed to support consumers so that they can make healthy food choices.
Fermentation of Blackberry with L. plantarum JBMI F5 Enhance the Protection Effect on UVB-Mediated Photoaging in Human Foreskin Fibroblast and Hairless Mice through Regulation of MAPK/NF-κB Signaling
Authors: Kim Ha-Rim , Jeong Da-Hye , Kim Sol , Lee Sang-Wang , Sin Hong-Sig , Yu Kang-Yeol , Jeong Seung-Il , Kim Seon-Young
Published: October 2019

Chronic and extensive exposure of ultraviolet (UV)-irradiation causes human skin sunburn, inflammation, or photoaging, which is associated with downregulated collagen synthesis. This study investigated the effects of fermented blackberry (Rubus fruticosus B., FBB) by Lactobacillus plantarum JBMI F5 (LP) on UVB-induced photoaging in human foreskin fibroblast (Hs68) as well as in SKH-1 hairless mice. FBB pretreatment inhibited UVB-mediated type-1 procollagen degradation, matrix metalloproteinase (MMP)-1 and MMP-2 protein expression, and suppressed nuclear factor-κB (NF-κB) activation as well as mitogen-activated protein kinase (MAPK) phosphorylation in Hs68. In addition, FBB administration diminished the wrinkle formation in dorsal skin and epidermal thickening in UVB-irradiated hairless mice. Moreover, UVB-induced Type-1 procollagen reduction and antioxidant enzyme inactivation were reversed by FBB administration. These results suggest that FBB may have antiphotoaging effects on UVB-induced wrinkle formation by maintaining the extracellular matrix density in the dermis, which occurs via regulation of reactive oxygen species and related MAPK and NF-κB signaling. Therefore, FBB can be a potential candidate for protecting skin aging against UV irradiation.
Ammonium Lignosulfonate Adhesives for Particleboards with pMDI and Furfuryl Alcohol as Crosslinkers
Authors: Hemmilä Venla , Adamopoulos Stergios , Hosseinpourpia Reza , Ahmed Sheikh Ali
Published: October 2019

Tightening formaldehyde emission limits and the need for more sustainable materials have boosted research towards alternatives to urea-formaldehyde adhesives for wood-based panels. Lignin residues from biorefineries consist of a growing raw material source but lack reactivity. Two crosslinkers were tested for ammonium lignosulfonate (ALS)—bio-based furfuryl alcohol (FOH) and synthetic polymeric 4,4′-diphenylmethane diisocyanate (pMDI). The addition of mimosa tannin to ALS before crosslinking was also evaluated. The derived ALS adhesives were used for gluing 2-layered veneer samples and particleboards. Differential Scanning Calorimetry showed a reduction of curing temperature and heat for the samples with crosslinkers. Light microscopy showed that the FOH crosslinked samples had thicker bondlines and higher penetration, which occurred mainly through vessels. Tensile shear strength values of 2-layered veneer samples glued with crosslinked ALS adhesives were at the same level as the melamine reinforced urea-formaldehyde (UmF) reference. For particleboards, the FOH crosslinked samples showed a significant decrease in mechanical properties (internal bond (IB), modulus of elasticity (MOE), modulus of rupture (MOR)) and thickness swelling. For pMDI crosslinked samples, these properties increased compared to the UmF. Although the FOH crosslinked ALS samples can be classified as non-added-formaldehyde adhesives, their emissions were higher than what can be expected to be sourced from the particles.
Piezoelastic PVDF/TPU Nanofibrous Composite Membrane: Fabrication and Characterization
Authors: Elnabawy Eman , Hassanain Ahmed H. , Shehata Nader , Popelka Anton , Nair Remya , Yousef Saifallah , Kandas Ishac
Published: October 2019

Poly (vinylidene fluoride) nanofibers (PVDF NFs) have been extensively used in energy harvesting applications due to their promising piezoresponse characteristics. However, the mechanical properties of the generated fibers are still lacking. Therefore, we are presenting in this work a promising improvement in the elasticity properties of PVDF nanofibrous membrane through thermoplastic polyurethane (TPU) additives. Morphological, physical, and mechanical analyses were performed for membranes developed from different blend ratios. Then, the impact of added weight ratio of TPU on the piezoelectric response of the formed nanofibrous composite membranes was studied. The piezoelectric characteristics were studied through impulse loading testing where the electric voltage had been detected under applied mass weights. Piezoelectric characteristics were investigated further through a pressure mode test the developed nanofibrous composite membranes were found to be mechanically deformed under applied electric potential. This work introduces promising high elastic piezoelectric materials that can be used in a wide variety of applications including energy harvesting, wearable electronics, self-cleaning filters, and motion/vibration sensors.
Anisotropic Thermally Conductive Perfluoroalkoxy Composite with Low Dielectric Constant Fabricated by Aligning Boron Nitride Nanosheets via Hot Pressing
Authors: Zhang Xinru , Cai Xinzhi , Xie Xiaoyu , Pu Changyu , Dong Xuanzuo , Jiang Zeyi , Gao Ting , Ren Yujie , Hu Jian , Zhang Xinxin
Published: October 2019

Thermal management has become a critical challenge in electronics and portable devices. To address this issue, polymer composites with high thermal conductivity (TC) and low dielectric property are urgently needed. In this work, we fabricated perfluoroalkoxy (PFA) composite with high anisotropic TC and low dielectric constant by aligning boron nitride nanosheets (BNNs) via hot pressing. We characterized the thermal stability, microstructure, in-plane and through-plane TCs, heat dissipation capability, and dielectric property of the composites. The results indicate that the BNNs–PFA composites possessed good thermal stability. When the BNNs content was higher than 10 wt %, the BNNs were well layer aligned in the PFA matrix, and the composites showed obvious anisotropic TC. The in-plane TC and through-plane TCs of 30 wt % BNNs–PFA composite were 4.65 and 1.94 W m−1 K−1, respectively. By using the composite in thermal management of high-power LED, we found that alignment of BNNs in composite significantly improves the heat dissipation capability of composite. In addition, the composites exhibited a low dielectric property. This study shows that hot pressing is a facile and low-cost method to fabricate bulk composite with anisotropic TC, which has wide applications in electronic packaging.
Facile Strategy of Improving Interfacial Strength of Silicone Resin Composites Through Self-Polymerized Polydopamine Followed via the Sol-Gel Growing of Silica Nanoparticles onto Carbon Fiber
Authors: Zheng Yawen , Wang Xiaoyun , Wu Guangshun
Published: October 2019

In the present research, to enhance interfacial wettability and adhesion between carbon fibers (CFs) and matrix resin, hydrophilic silica nanoparticles (SiO2) were utilized to graft the surface of CFs. Polydopamine (PDA) as a “bio-glue” was architecturally built between SiO2 and CFs to obtain a strong adhesion strength and homogenous SiO2 distribution onto the surface of CFs. The facile modification strategy was designed by self-polymerization of dopamine followed by the hydrolysis of tetraethoxysilane (TEOS) onto carbon fibers. Surface microstructures and interfacial properties of CFs, before and after modification, were systematically investigated. The tight and homogeneous coverage of SiO2 layers onto the CF surface, with the assistance of a PDA layer by self-polymerization of dopamine, significantly enhanced fiber surface roughness and wettability, resulting in an obvious improvement of mechanical interlocking and interfacial interactions between CFs and matrix resin. The interlaminar shear strength (ILSS) and the interfacial shear strength (IFSS) of CF/PDA/SiO2 reinforced composites exhibited 57.28% and 41.84% enhancements compared with those of untreated composites. In addition, impact strength and the hydrothermal aging resistance of the resulting composites showed great improvements after modification. The possible reinforcing mechanisms during the modification process have been discussed. This novel strategy of developed SiO2-modified CFs has interesting potential for interfacial improvements for advanced polymer composites.
Highly Sensitive Detection of Benzoyl Peroxide Based on Organoboron Fluorescent Conjugated Polymers
Authors: Yin Mingyuan , Zhang Caiyun , Li Jing , Li Haijie , Deng Qiliang , Wang Shuo
Published: October 2019

The method capable of rapid and sensitive detection of benzoyl peroxide (BPO) is necessary and receiving increasing attention. In consideration of the vast signal amplification of fluorescent conjugated polymers (FCPs) for high sensitivity detection and the potential applications of boron-containing materials in the emerging sensing fields, the organoboron FCPs, poly (3-aminophenyl boronic acid) (PABA) is directly synthesized via free-radical polymerization reaction by using the commercially available 3-aminophenyl boronic acid (ABA) as the functional monomer and ammonium persulfate as the initiator. PABA is employed as a fluorescence sensor for sensing of trace BPO based on the formation of charge-transfer complexes between PABA and BPO. The fluorescence emission intensity of PABA demonstrates a negative correlation with the concentration of BPO. And a linear range of 8.26 × 10−9 M–8.26 × 10–4 M and a limit of detection of 1.06 × 10–9 M as well as a good recovery (86.25%–111.38%) of BPO in spiked real samples (wheat flour and antimicrobial agent) are obtained. The proposed sensor provides a promising prospective candidate for the rapid detection and surveillance of BPO.
Recent Advances in Skin Chemical Sensors
Authors: Piro Benoît , Mattana Giorgio , Noël Vincent
Published: October 2019

This review summarizes the latest developments in the field of skin chemical sensors, in particular wearable ones. Five major applications are covered in the present work: (i) sweat analysis, (ii) skin hydration, (iii) skin wounds, (iv) perspiration of volatile organic compounds, and (v) general skin conditions. For each application, the detection of the most relevant analytes is described in terms of transduction principles and sensor performances. Special attention is paid to the biological fluid collection and storage and devices are also analyzed in terms of reusability and lifetime. This review highlights the existing gaps between current performances and those needed to promote effective commercialization of sensors; future developments are also proposed.
Forensic Speaker Verification Using Ordinary Least Squares
Authors: Machado Thyago J. , Vieira Filho Jozue , de Oliveira Mario A.
Published: October 2019

In Brazil, the recognition of speakers for forensic purposes still relies on a subjectivity-based decision-making process through a results analysis of untrustworthy techniques. Owing to the lack of a voice database, speaker verification is currently applied to samples specifically collected for confrontation. However, speaker comparative analysis via contested discourse requires the collection of an excessive amount of voice samples for a series of individuals. Further, the recognition system must inform who is the most compatible with the contested voice from pre-selected individuals. Accordingly, this paper proposes using a combination of linear predictive coding (LPC) and ordinary least squares (OLS) as a speaker verification tool for forensic analysis. The proposed recognition technique establishes confidence and similarity upon which to base forensic reports, indicating verification of the speaker of the contested discourse. Therefore, in this paper, an accurate, quick, alternative method to help verify the speaker is contributed. After running seven different tests, this study preliminarily achieved a hit rate of 100% considering a limited dataset (Brazilian Portuguese). Furthermore, the developed method extracts a larger number of formants, which are indispensable for statistical comparisons via OLS. The proposed framework is robust at certain levels of noise, for sentences with the suppression of word changes, and with different quality or even meaningful audio time differences.
A New Centralized Clustering Algorithm for Wireless Sensor Networks
Authors: Cuevas-Martinez Juan-Carlos , Yuste-Delgado Antonio-Jesus , Leon-Sanchez Antonio-Jose , Saez-Castillo Antonio-Jose , Triviño-Cabrera Alicia
Published: October 2019

Clustering is presently one of the main routing techniques employed in randomly deployed wireless sensor networks. This paper describes a novel centralized unequal clustering method for wireless sensor networks. The goals of the algorithm are to prolong the network lifetime and increase the reliability of the network while not compromising the data transmission. In the proposed method, the Base Station decides on the cluster heads according to the best scores obtained from a Type-2 Fuzzy system. The input parameters of the fuzzy system are estimated by the base station or gathered from the network with a careful design that reduces the control message exchange. The whole network is controlled by the base station in a rounds-based schedule that alternates rounds when the base station elects cluster heads, with other rounds in which the cluster heads previously elected, gather data from their contributing nodes and forward them to the base station. The setting of the number of rounds in which the Base Station keeps the same set of cluster heads is another contribution of the present paper. The results show significant improvements achieved by the proposal when compared to other current clustering methods.
Fast and Accurate 3D Measurement Based on Light-Field Camera and Deep Learning
Authors: Ma Haoxin , Qian Zhiwen , Mu Tingting , Shi Shengxian
Published: October 2019

The precise combination of image sensor and micro-lens array enables light-field cameras to record both angular and spatial information of incoming light, therefore, one can calculate disparity and depth from one single light-field image captured by one single light-field camera. In turn, 3D models of the recorded objects can be recovered, which means a 3D measurement system can be built using a light-field camera. However, reflective and texture-less areas in light-field images have complicated conditions, making it hard to correctly calculate disparity with existing algorithms. To tackle this problem, we introduce a novel end-to-end network VommaNet to retrieve multi-scale features from reflective and texture-less regions for accurate disparity estimation. Meanwhile, our network has achieved similar or better performance in other regions for both synthetic light-field images and real-world data compared to the state-of-the-art algorithms.
Dynamic Consolidation Measurements in a Well Field Using Fiber Bragg Grating Sensors
Authors: Drusová Sandra , Wagterveld R. Martijn , Wexler Adam D. , Offerhaus Herman L.
Published: October 2019

Currently available groundwater flow prediction tools and methods are limited by insufficient spatial resolution of subsurface data and the unknown local heterogeneity. In this field study, fiber Bragg grating (FBG) sensors were installed in an extraction well field to investigate its potential to measure groundwater flow velocity. Reference in-situ pore pressure and temperature measurements were used to identify possible sources of FBG responses. FBG strain sensors were able to detect soil consolidation caused by groundwater extraction from 250 m distance. The results show that FBG responses were influenced by interface friction between soil and FBG packaging. FBG packaging slipped in soil and the effect was more pronounced during higher groundwater flow around a nearby well. These FBG fibers could be applied for indirect flow monitoring that does not require any tracer and provide real-time and long-term data during regular operation of extraction wells.
Virtualization of Industrial Real-Time Networks for Containerized Controllers
Authors: Lee Sang-Hun , Kim Jong-Seo , Seok Jong-Soo , Jin Hyun-Wook
Published: October 2019

The virtualization technology has a great potential to improve the manageability and scalability of industrial control systems, as it can host and consolidate computing resources very efficiently. There accordingly have been efforts to utilize the virtualization technology for industrial control systems, but the research for virtualization of traditional industrial real-time networks, such as Controller Area Network (CAN), has been done in a very limited scope. Those traditional fieldbuses have distinguished characteristics from well-studied Ethernet-based networks; thus, it is necessary to study how to support their inherent functions transparently and how to guarantee Quality-of-Service (QoS) in virtualized environments. In this paper, we suggest a lightweight CAN virtualization technology for virtual controllers to tackle both functionality and QoS issues. We particularly target the virtual controllers that are containerized with an operating-system(OS)-based virtualization technology. In the functionality aspect, our virtualization technology provides virtual CAN interfaces and virtual CAN buses at the device driver level. In the QoS perspective, we provide a hierarchical real-time scheduler and a simulator, which enable the adjustment of phase offsets of virtual controllers and tasks. The experiment results show that our CAN virtualization has lower overheads than an existing approach up to 20%. Moreover, we show that the worst-case end-to-end delay could be reduced up to 78.7% by adjusting the phase offsets of virtual controllers and tasks.
Hierarchical Open-Set Object Detection in Unseen Data
Authors: Kim Yeong Hyeon , Shin Dong Kyun , Ahmed Minhaz Uddin , Rhee Phill Kyu
Published: October 2019

In this paper, we propose an open-set object detection framework based on a dynamic hierarchical structure with incremental learning capabilities for unseen object classes. We were motivated by the observation that deep features extracted from visual objects show a strong hierarchical clustering property. The hierarchical feature model (HFM) was used to learn a new object class by using collaborative sampling (CS), and open-set-aware active semi-supervised learning (ASSL) algorithms. We divided object proposals into superclasses by using the agglomerative clustering algorithm. Data samples in each superclass node were classified into multiple augmented class nodes instead of directly associating with regular object classes. One or more augmented class nodes are related to a regular object class, and each augmented class has only one superclass. Object proposals from inexperienced data distribution are assigned to an augmented class node. Dynamic HFM nodes in the decision path are assembled to constitute an ensemble prediction, and the new augmented object is associated with a new regular object class. Our experimental results showed that the proposed method uses standard benchmark datasets such as PASCAL VOC, MS COCO, ILSVRC DET, and local datasets to perform better than state-of-the-art techniques.
Promise and the Pharmacological Mechanism of Botulinum Toxin A in Chronic Prostatitis Syndrome
Authors: Chen Chien-Hsu , Tyagi Pradeep , Chuang Yao-Chi
Published: October 2019

Chronic prostatitis/chronic pelvic pain syndrome (CP/ CPPS) has a negative impact on the quality of life, and its etiology still remains unknown. Although many treatment protocols have been evaluated in CP/CPPS, the outcomes have usually been disappointing. Botulinum neurotoxin A (BoNT-A), produced from Clostridium botulinum, has been widely used to lower urinary tract dysfunctions such as detrusor sphincter dyssynergia, refractory overactive bladder, interstitial cystitis/bladder pain syndromes, benign prostatic hyperplasia, and CP/ CPPS in urology. Here, we review the published evidence from animal models to clinical studies for inferring the mechanism of action underlying the therapeutic efficacy of BoNT in CP/CPPS. Animal studies demonstrated that BoNT-A, a potent inhibitor of neuroexocytosis, impacts the release of sensory neurotransmitters and inflammatory mediators. This pharmacological action of BoNT-A showed promise of relieving the pain of CP/CPPS in placebo-controlled and open-label BoNT-A and has the potential to serve as an adjunct treatment for achieving better treatment outcomes in CP/CPPS patients.
Tyrosine Kinases in Helicobacter pylori Infections and Gastric Cancer
Authors: Chichirau Bianca E. , Diechler Sebastian , Posselt Gernot , Wessler Silja
Published: October 2019

Helicobacter pylori (H. pylori) has been identified as a leading cause of gastric cancer, which is one of the most frequent and malignant types of tumor. It is characterized by its rapid progression, distant metastases, and resistance to conventional chemotherapy. A number of receptor tyrosine kinases and non-receptor tyrosine kinases have been implicated in H. pylori-mediated pathogenesis and tumorigenesis. In this review, recent findings of deregulated EGFR, c-Met, JAK, FAK, Src, and c-Abl and their functions in H. pylori pathogenesis are summarized.
Cross-Protection of Inactivated Rabies Vaccines for Veterinary Use against Bat Lyssaviruses Occurring in Europe
Authors: Servat Alexandre , Wasniewski Marine , Cliquet Florence
Published: October 2019

Human rabies vaccines have been shown to induce partial protection against members of phylogroup I bat lyssaviruses. Here, we investigated the capacity of a widely used rabies inactivated vaccine (Rabisin, Boehringer-Ingelheim) for veterinary use to cross-protect mice experimentally infected with European bat lyssavirus 1 (EBLV-1b), European bat lyssavirus 2 (EBLV-2), and Bokeloh bat lyssavirus (BBLV) occurring in Europe. For each lyssavirus, we investigated the efficacy of two different doses of vaccine against two viral doses administrated by either central or peripheral routes. In parallel, seroconversion following pre-exposure vaccination was investigated. In this study, we demonstrated that the three investigated bat isolates were pathogenic, even at low dose, when inoculated by the central route but were not/less pathogenic when administrated peripherally. The Rabisin vaccine was capable of significantly cross-protecting mice inoculated intramuscularly with EBLV-1b and EBLV-2 and intracerebrally with BBLV. The level of rabies neutralizing antibodies induced by the Rabisin was quite high against the bat lyssaviruses, but with no significant differences between immunization with 1 and 5 IU/dose. The study emphasizes that the quality of rabies-inactivated vaccines for veterinary use is of utmost importance to optimize the cross-protection of pets against phylogroup I bat lyssaviruses occurring in Europe.
High Fidelity Deep Sequencing Reveals No Effect of ATM, ATR, and DNA-PK Cellular DNA Damage Response Pathways on Adenovirus Mutation Rate
Authors: Risso-Ballester Jennifer , Sanjuán Rafael
Published: October 2019

Most DNA viruses exhibit relatively low rates of spontaneous mutation. However, the molecular mechanisms underlying DNA virus genetic stability remain unclear. In principle, mutation rates should not depend solely on polymerase fidelity, but also on factors such as DNA damage and repair efficiency. Most eukaryotic DNA viruses interact with the cellular DNA damage response (DDR), but the role of DDR pathways in preventing mutations in the virus has not been tested empirically. To address this goal, we serially transferred human adenovirus type 5 in cells in which the telangiectasia-mutated PI3K-related protein kinase (ATM), the ATM/Rad3-related (ATR) kinase, and the DNA-dependent protein kinase (DNA-PK) were chemically inactivated, as well as in control cells displaying normal DDR pathway functioning. High-fidelity deep sequencing of these viral populations revealed mutation frequencies in the order of one-millionth, with no detectable effect of the inactivation of DDR mediators ATM, ATR, and DNA-PK on adenovirus sequence variability. This suggests that these DDR pathways do not play a major role in determining adenovirus genetic diversity.
EVALUASI KUALITAS LAYANAN PERPUSTAKAAN UNIVERSITAS ISLAM AS SYAFI’IYAH (UIA)
Authors: Budiningsih Iffah
Published: October 2019

The purpose of this evaluation study is to know the extent to which the quality of library service – UIA inorder to support the learning process for the students of the UIA's next get what information should be improved inthe manifest ' prima ' library services. The object of this research is a student is a student of Strata program S1 in 6(six) faculty (FE, FAI, PEDAGOGY, FH, FST, FIKES) semester 7 (seven) FY 2015/2016 on The Islamic Syafi'iyahUniversity Jakarta (UIA); the number of samples of 84 students. Library service quality evaluation of variablesmeasured using instruments non test by questionnaire.The Data collected is processed and analyzed using descriptive analysis , i.e., Using a central tendency:size: mean, median, mode and size dispersion: score the minimum, maximum, standard deviation score. Theanalysis of statistical data is done with the help of program Excels and 11.5 version SPSS for windowsThe results of research on the quality evaluation of UIA library services can be explained that the average(mean) library service quality score achieved score 59.67 included in categories of "enough". The value of themedian (middle value) score the quality of library services achieve a score 59.0; This gives a meaning that 50%quality of library services show score above 59.0 or above reasonably and 50% of his show score under 59.0 underenough. The value of the mode of 60.0; this indicates that the in General, students give an assessment of the qualityof library services "enough". The lowest score of the quality of service library of 42.0 and highest score achieved,meaning there were 89.0 students who rated lowest 42.0 or "enough" and there are students who rated highest 89.0or "excellent" ,The conclusions of the research library service quality upon evaluative UIA is: 1). In general the quality oflibrary services UIA rated by students in the categories of ' enough '; 2) Assessment of the students in the categoriesof ' enough ' giving opportunities to management library for working to improve the quality of its services for beinga requirement of ' good '; 3) Managing a library to become ' learning resource centre ' among the students andteachers not only required UIA sufficient funds, but also required the managers ' creative and innovative ' inaccordance with the progress of the IPTEKS.
Approche thermodynamique des phénomènes de dissolution. Aspect cinétique en système ouvert
Authors: Massard Pierre
Published: October 2019

A partir des résultats expérimentaux existants, nous proposons un mécanisme général de la dissolution d'un minéral dans une solution altérante. Ce mécanisme suppose principalement la congruence de la réaction chimique hétérogène de la dissolution, laquelle est couplée aux phénomènes de diffusion en solution. L'utilisation de la Thermodynamique des Processus Irréversibles dans le domaine linéaire permet alors d'aboutir à une loi cinétique très simple, valable que le système soit ouvert ou fermé : v = k A/T où v est la cinétique, A l'affinité chimique de la réaction de dissolution, T la température et k une constante dans laquelle figure un paramètre caractéristique du minéral altéré. Des expériences effectuées conjointement en système ouvert, dans le cas simple d'un verre d'obsidienne, confirment qualitativement les hypothèses de cette étude.
Structure des péridotites en enclaves dans les kimberlites d'Afrique du Sud. Conséquences sur la constitution du manteau supérieur
Authors: Boullier Anne-Marie
Published: October 2019

Les péridotites en enclaves dans les kimberlites sont classées en sept types structuraux qui constituent trois grands groupes : structures à gros grain (équante et tabulaire), structures de tectonite (porphyroclastique, en mosaïque et en mosaïque fluidale) et enfin structures secondaires (tabulaire et à gros grain), qui correspondent à différents états du manteau supérieur. Cette classification est fondée essentiellement sur l'olivine qui est le minéral le plus abondant, le plus ductile, et le mieux connu du manteau supérieur.

On compare les cortèges d'enclaves des différents pipes entre eux, puis les xénolites des kimberlites avec ceux des basaltes : il en résulte que les structures de tectonite des premiers correspondent à des taux de déformation et des contraintes plus élevées que celles des seconds.
Trends in Dry Pea (Pisum sativum L.) Production
Authors: Lazányi János
Published: October 2019

Dry pea is an important, cool-season grain legume, which is grown worldwide on over 6 million hectares. The major producing countries outside Europe are China and Canada, followed by India, Australia, and the United States. France, Canada and Australia produce over 2 million hectares and are major exporters of peas. During the 1980’s, in developed countries of the European Union, pea production rose yearly by 6-10%, which represents a significant increase in both area and yield. Europe accounts for 50-75% of world pea production. In the 1990’s, the European Union produced 4-5 million tonnes of dry pea, of which 3-4 million tonnes were used for feed and 1 million tonnes for export. At the end of the 20th century, the growth in production was low, mainly because of the absence of support measures, and the better returns offered by other crops. In the countries of the former Soviet Union, dry pea was primarily used as feed and pea production dropped, due to a trend in livestock raising.Food consumption of dry pea is concentrated in developing countries, where grain legumes represent a useful complement to cereal-based diets as a relatively inexpensive source of high quality protein. As a result, human consumption of grain legumes fell from 2,2 kg/capita in 1961 to 0,5 kg/capita in 1999. The importance of grain legumes in food protein supply decreased, while that of cereal products increased. Shortage of grain legumes has adverse effects on the nutritional standard of poor people in developing countries.World dry pea production reached 16,7 million tonnes in 1990, with 3,7 million tonnes used as food, 11,4 million tonnes used as feed, and 1,0 million tonnes used as seed. Dry pea production was 10,9 million tonnes in 1999, and 3,5, 5,8 and 0,8 million tonnes was used as food, feed and seed, respectively. In the coming decades, world grain legume production and utilization as feed are expected to expand at a slower rate than in the 1980’s. Most of the increase is expected to occur in Eastern European countries, Canada and Australia, where production is anticipated to grow at 2% annually. The projection for the new millennium was derived from adjusted trends in area and yield over the period 1961-2000, based on FAO statistical data.
The Natural, Social and Economic Conditions and Opportunities for Development of Balmazujvaros, Especially in the Case of the Co-operative Kvaliko
Authors: Szabó Bernadett , Klutsik Andrea
Published: October 2019

Balmazujvaros as a settlement near Hortobagy has to cope with both advantages and disadvantages. Its natural and social conditions are mainly given, the agricultural characteristic is dominant, and the number of the employed is the highest in the agricultural firms and processing industry. Developing the third sector, including hosting, tourism, eco-tourism, thermal-tourism, may be an opportunity for the city. The subsidy for rural development relating to the SAPARD-programme may contribute to this, as the city is the member of the Association of Hajdu Towns.The agriculture plays an important part in Balmazujvaros in which production and marketing of vegetables and fruits excel. Several farmers realised this opportunity and founded the Marketing Co-operative of Vegetable Producers in Eastern Hungary, that is the Kvaliko. This PO works in a Corporation form and is constantly developing, spreading and expanding its choice making use of the local natural, social and economic conditions and applications for realising its investments. This PO may set an example for the other entrepreneurs and farmers of Balmazujvaros to co-operate and it may be considered as an already realised opportunity.
A Few Thoughts About the Implementation of Sustainability in Hungary
Authors: Láng István
Published: October 2019

UN Conference on Environment and Development óta (1992 Rio de Janeiro) a sustainable development fogalma bevonult a nemzetközi szervezetek és a nemzeti kormányok programjaiba. A fenntartható fejlődés megvalósítására sok országban stratégiákat dolgoztak ki. Magyarországon ilyen stratégiai a dokumentum ma még nincs, de valószínű, hogy rövidesen elkészül. A szerző ehhez az előkészítő folyamathoz kíván hozzájárulni javaslataival. A fenntarthatóság (sustainability) megvalósításához hosszú időre és konkrét cselekvési programok összefüggő láncolatára van szükség. A szerző javaslatai szerint a következő 3-5 évben tíz prioritást célszerű támogatni a kormány és a civil társadalom részéről:1. Környezetvédelem2. Környezeti nevelés és tudatformálás3. A szemét, a hulladék eltávolítása és hasznosítása4. Környezet-egészségügy5. Környezetbiztonság6. A közlekedés korszerűsítése7. Agrár-környezetvédelem8. Környezetbarát technológiák és termékek9. Lakossági részvétel a döntés-előkészítésben és döntéshozatalban10. Az állami és önkormányzati költségvetések szerepe
Lifestyle of Mullai land ethnic group
Authors: V Ramarajapandiyan , K Karuppusamy
Published: October 2019

Forest and surrounding areas are called ‘Mullai’. This is an elevated land suitable for cattle rearing occupation of the ‘Mullai’ people. Ancient Tamil society represents the life styles of many ethnic groups. The five land regions represent one ethnic group each.  The ‘Mullai’ ethnic group people are called ‘ Idaiyars’. The vestiges of the ‘Mullai’ idaiyar people through ages until today have reflections in the society. This article tries to study the life style of the ‘mullai’ ethnic group through Sangam poetry.
MENINGKATKAN KEMAMPUAN KONEKSI MATEMATIK SISWA SMP DENGAN MENGGUNAKAN PENDEKATAN REALISTIC MATHEMATIS EDUCATION
Authors: Wulandari Neneng Yulia
Published: October 2019

Penelitian ini dilatarbelakangi oleh rendahnya kemampuan koneksi matematik siswa SMP. Penelitian ini bertujuan untuk menelaah pencapaian dan peningkatan kemampuan koneksi matematik siswa SMP yang pembelajarannya menggunakan pendekatan Realistic Mathematis Education dibandingkan dengan yang menggunakan pembelajaran biasa. Metode pada penelitian ini adalah metode eksperimen dengan desain penelitian pretes-postes. Populasi dalam penelitian ini adalah siswa SMP AL-Madina Cianjur, sedangkan sampel penelitiannya yaitu kelas VII  yang dipilih secara acak dari salah satu SMP di Cianjur dan terpilih kelas VII A sebagai kelas eksperimen dan kelas VII C sebagai kelas kontrol. Kelas eksperimen menggunakan pembelajaran dengan pendekatan Realistic Mathematis Education sedangkan kelas kontrol menggunakan pembelajaran biasa. Instrumen dalam penelitian ini adalah seperangkat soal tes kemampuan koneksi matematik yang terdiri dari lima soal tes uraian, data yang akan diolah dalam penelitian ini adalah skor pretes, postes, dan N-gain yang diolah menggunakan bantuan sofware SPSS 16 dan Minitab 16. Hasil penelitian yang diperoleh yaitu pencapaian kemampuan  koneksi matematik siswa SMP yang pembelajarannya menggunakan pendekatan Realistic Mathematis Education lebih baik daripada yang menggunakan pembelajaran biasa, peningkatan kemampuan koneksi matematik siswa SMP yang pembelajarannya menggunakan pendekatan Realistic Mathematis Education lebih baik daripada yang menggunakan pembelajaran biasa, serta implementasi langkah-langkah pembelajaran dengan menggunakan pendekatan Realistic Mathematis Education di lapangan sudah terlaksana. Kata kunci: Koneksi Matematik, Pendekatan Realistic Mathematis Education
IMPLEMENTASI PEMBELAJARAN STUDENT FACILITATOR AND EXPLAINING UNTUK MENUMBUNHKAN SIKAP SELF AWARANESS SISWA SMA
Authors: IDA NURAIDA, YONI SUNARYO
Published: October 2019

Penelitian ini dilatarbelakangi oleh adanya fakta di lapangan bahwa pembelajaran matematika di sekolah hanya diberikan secara konvensional, siswa tidak dilibatkan dalam menemukan konsep-konsep yang pada akhirnya siswa hanya mengikuti prosedur dan proses penghapalan rumus, maka terjadilah pembelajaran yang berpusat pada guru. Rumusan masalah pada penelitian ini adalah apakah self awareness siswa yang mendapatkan pembelajaran student facilitator and explaining lebih baik dari pada siswa yang mendapatkan pembelajaran secara konvensional. Desain penelitian ini adalah kelompok eksperimen dengan kelompok kontrol pretes dan postes. Kelompok eksperimen mendapat pembelajaran student facilitator and explaining dan kelompok kontrol mendapat pembelajaran konvensional. Pada penelitian ini untuk mendapatkan data hasil penelitian digunakan instrumen skala self awareness siswa, lembar observasi dan wawancara. Seluruh siswa kelas XI IPA pada salah satu SMA yang ada di belahan utara kabupaten Tasikmalaya yang dipilih secara purposive. Analisis data dilakukan secara kuantitatif dan kualitatif. Analisis kualitatif dilakukan untuk menganalisis profil skala self awareness siswa kedua kelompok secara keseluruhan yang terdapat tiga aspek. Analisis kualitatif dilakukan juga untuk menganalisis hasil observasi siswa dan hasil wawancara siswa. Hasil penelitian menunjukkan bahwa hasil skala self awareness pada pembelajaran student facilitator and explaining lebih baik daripada kelompok siswa yang mendapat pembelajaran konvensional.
PENGARUH STRATEGI PEMBELAJARAN KEATIF – PRODUKTIF TERHADAP HASIL BELAJAR MATEMATIKA SISWA
Authors: YUDI YUNIKA PUTRA
Published: October 2019

Tujuan penelitian ini adalah untuk mengetahui pengaruh strategi pembelajaran kreatif-produktif terhadap hasil belajar siswa dalam pembelajaran matematika kelas X SMAN 6 Bandar Lampung dan apakah rata-rata hasil belajar matematika siswa yang menggunakan strategi pembelajaran kreatif-produktif lebih tinggi dibandingkan dengan rata-rata hasil belajar matematika siswa yang tidak menggunakan strategi pembelajaran kreatif-produktif. Metode penelitian ini adalah eksperimen kuantitatif. Sampel dalam penelitian ini adalah siswa kelas X.1 dan siswa kelas X.3 SMAN 6 Bandar Lampung dengan berturut-turut sebagai kelas eksperimen dan kelas kontrol. Teknik pengumpulan data dalam penelitian berupa tes yang dianalisis berdasarkan nilai perbutir soal. Dalam penelitian ini didapatkan bahwa berdasarkan hasil pengujian hipotesis dengan mengunakan rumus statistik t-tes didapat t=  3,71 dan dari tabel distribusi t pada taraf signitifikan 0,05 diketahui ttab = t(1 – ½ α)  = 2,00   dan t(1 – α)  = 1,67   berarti t> t, maka dengan ini dapat disimpulkan bahwa penerapan  strategi pembelajaran kreatif-produktif berpengaruh positif terhadap hasil belajar matematika siswa.
KREATIVITAS GURU DALAM MEMBUAT DAN MEMANFAATKAN MEDIA VISUAL UNTUK ANAK KELOMPOK B2 DI TK NEGERI PEMBINA PUDING BESAR KECAMATAN PUDING BESAR KABUPATEN BANGKA
Authors: Rismawati, S.Pd
Published: October 2019

Tujuan penelitian ini adalah untuk mendeskripsikan kreativitas guru dalam membuat media visual untuk anak kelompok B2 di TK Negeri Pembina Puding Besar, mendeskripsikan kreativitas guru dalam memanfaatkan media visual untuk anak, dan untuk mengetahui hasil kreativitas guru dalam membuat dan memanfaatkan media visual untuk anak kelompok B2 di TK Negeri Pembina Puding Besar Kecamatan Puding Besar Kabupaten Bangka. Jenis penelitian ini adalah penelitian kualitatif. Kemudian data dianalisis dengan menggunakan analisis data deskriptif yakni menyusun data yang diperoleh dari hasil observasi (pengamatan), wawancara, dan dokumentasi secara sistematis dengan mengkategorikan data-data yang berhubungan dengan penelitian. Hasil dari kreativitas guru dalam membuat dan memanfaatkan media visual untuk anak digunakan untuk mengembangkan segenap dimensi kemampuan pada anak seperti kemampuan kognitif anak, pengembangan motorik halus anak, pengembangan kreativitas/daya pikir/daya cipta anak, menstimulasi indera penglihatan anak, pengembangan kemampuan seni anak, pengenalan lambang bilangan, bentuk-bentuk geometri, dapat mengembangkan kemampuan bahasa anak, dan pengembangan kemampuan sosial-emosional anak.