bluuebunny/crossref_metadata_2025 huggingface dataset:
Strengthening the Evidence for a Causal Link between Type 2 Diabetes Mellitus and Pancreatic Cancer: Insights from Two-Sample and Multivariable Mendelian Randomization
Authors: Ke Te-Min , Lophatananon Artitaya , Muir Kenneth R.
Published: April 2024

This two-sample Mendelian randomization (MR) study was conducted to investigate the causal associations between type 2 diabetes mellitus (T2DM) and the risk of pancreatic cancer (PaCa), as this causal relationship remains inconclusive in existing MR studies. The selection of instrumental variables for T2DM was based on two genome-wide association study (GWAS) meta-analyses from European cohorts. Summary-level data for PaCa were extracted from the FinnGen and UK Biobank databases. Inverse variance weighted (IVW) and four other robust methods were employed in our MR analysis. Various sensitivity analyses and multivariable MR approaches were also performed to enhance the robustness of our findings. In the IVW and Mendelian Randomization Pleiotropy RESidual Sum and Outlier (MR-PRESSO) analyses, the odds ratios (ORs) for each 1-unit increase in genetically predicted log odds of T2DM were approximately 1.13 for PaCa. The sensitivity tests and multivariable MR supported the causal link between T2DM and PaCa without pleiotropic effects. Therefore, our analyses suggest a causal relationship between T2DM and PaCa, shedding light on the potential pathophysiological mechanisms of T2DM’s impact on PaCa. This finding underscores the importance of T2DM prevention as a strategy to reduce the risk of PaCa.
TRIM44 Promotes Rabies Virus Replication by Autophagy-Dependent Mechanism
Authors: He Hongling , Cai Ting , Chen Qiaozhu , Chen Zilian , Zhang Boyue , Chen Changyi , Wang Yueze , Liu Yan , Wang Yueming , Luo Yongwen , Huang Shile , Luo Jun , Guo Xiaofeng
Published: April 2024

Tripartite motif (TRIM) proteins are a multifunctional E3 ubiquitin ligase family that participates in various cellular processes. Recent studies have shown that TRIM proteins play important roles in regulating host–virus interactions through specific pathways, but their involvement in response to rabies virus (RABV) infection remains poorly understood. Here, we identified that several TRIM proteins are upregulated in mouse neuroblastoma cells (NA) after infection with the rabies virus using RNA-seq sequencing. Among them, TRIM44 was found to regulate RABV replication. This is supported by the observations that downregulation of TRIM44 inhibits RABV replication, while overexpression of TRIM44 promotes RABV replication. Mechanistically, TRIM44-induced RABV replication is brought about by activating autophagy, as inhibition of autophagy with 3-MA attenuates TRIM44-induced RABV replication. Additionally, we found that inhibition of autophagy with rapamycin reverses the TRIM44-knockdown-induced decrease in LC3B expression and autophagosome formation as well as RABV replication. The results suggest that TRIM44 promotes RABV replication by an autophagy-dependent mechanism. Our work identifies TRIM44 as a key host factor for RABV replication, and targeting TRIM44 expression may represent an effective therapeutic strategy.
Ectomycorrhizal Diversity and Exploration Types in Salix caprea
Authors: Hrynkiewicz Katarzyna , Furtado Bliss Ursula , Szydɫo Jagoda , Baum Christel
Published: April 2024

The tree species Salix caprea shows high adaptability to different habitat conditions and is economically valuable as a woody crop for biomass production. Moreover, S. caprea is dependent on mycorrhizal fungi, which are crucial for its growth and adaptability in different environments. Hence, this study explores the ectomycorrhizal diversity of S. caprea by utilizing the taxonomy (morphotyping and a molecular approach using the ITS and LSU regions) and trait diversity (exploration types) at two test sites in Germany and Poland. In total, 19 ectomycorrhizal (EM) morphotypes of S. caprea were characterized. Seven taxa were identified at the species level (Hebeloma populinum, Cortinarius atrocoerulaeus, Inocybe hirtella, Laccaria cf. ochropurpurea, Tuber maculatum, Cenococcum geophilum, and Phialophora finlandia) and twelve at the genus level (Tomentella spp. 1–8, Hebeloma sp. 1, Inocybe sp. 1, and Tuber spp. 1–2). The EM colonization ranged from 14 to 28% of the fine root tips. At both test sites, the largest portion of the total EM colonization consisted of Thelephoraceae. The exploration types were classified as medium-distance smooth (Tomentella sp. 1–8 and L. ochropurpurea) and medium-distance fringe (C. atrocoerulaeus), while the other taxa were short-distance exploration types, highlighting their potential functional role in the adaptation and growth of S. caprea.
Treatment of Acute Kidney Injury: A Review of Current Approaches and Emerging Innovations
Authors: Tamargo Christina , Hanouneh Mohamad , Cervantes C. Elena
Published: April 2024

Acute kidney injury (AKI) is a complex and life-threatening condition with multifactorial etiologies, ranging from ischemic injury to nephrotoxic exposures. Management is founded on treating the underlying cause of AKI, but supportive care—via fluid management, vasopressor therapy, kidney replacement therapy (KRT), and more—is also crucial. Blood pressure targets are often higher in AKI, and these can be achieved with fluids and vasopressors, some of which may be more kidney-protective than others. Initiation of KRT is controversial, and studies have not consistently demonstrated any benefit to early start dialysis. There are no targeted pharmacotherapies for AKI itself, but some do exist for complications of AKI; additionally, medications become a key aspect of AKI management because changes in renal function and dialysis support can lead to issues with both toxicities and underdosing. This review will cover existing literature on these and other aspects of AKI treatment. Additionally, this review aims to identify gaps and challenges and to offer recommendations for future research and clinical practice.
Serum Albumin as an Independent Predictor of Long-Term Survival in Patients with Recurrent and Metastatic Head and Neck Squamous Cell Carcinoma Treated with Nivolumab
Authors: Suzuki Shinsuke , Taguchi Yukie , Kitabayashi Takuro , Sato Nobuko , Kaya Haruka , Abe Tomoe , Endo Tentaro , Suzuki Hitomi , Kawasaki Yohei , Yamada Takechiyo
Published: April 2024

Background: Nivolumab has been shown to improve the overall survival (OS) of patients with recurrent and metastatic head and neck squamous cell carcinoma (R/M HNSCC). However, there is a need to identify factors associated with long-term survival (beyond 2 years) in these patients. This study investigated the relationship between pretreatment factors and long-term survival in patients with R/M HNSCC treated with nivolumab. Methods: Forty-nine patients with R/M HNSCC who were treated with nivolumab were retrospectively reviewed. Baseline characteristics, clinical data, and survival outcomes were evaluated. Univariate and multivariate analyses were performed to identify factors associated with long-term survival (OS ≥ 2 years). Results: The median OS in the overall cohort was 11.0 months, and the 2-year survival rate was 34.7%. Long-term survivors (OS ≥ 2 years) had significantly higher proportions of patients with Eastern Cooperative Oncology Group (ECOG) performance status (PS) scores of 0 or 1, serum albumin levels ≥ 3.5 g/dL, and neutrophil-to-eosinophil ratio (NER) < 32.0 compared to non-long-term survivors. On multivariate analysis, serum albumin levels ≥ 3.5 g/dL, in addition to ECOG-PS score of 0 or 1, were independent predictors of long-term survival. Conclusions: Pretreatment serum albumin levels may be useful for predicting long-term survival in R/M HNSCC patients treated with nivolumab.
Integrating Pharmacomechanical Treatments for Pulmonary Embolism Management within a Hub-and-Spoke System in the Swiss Ticino Region
Authors: Guarnieri Gianluca , Constantin Filip David , Pedrazzini Giovanni , Ruffino Maria Antonella , Sürder Daniel , Petrino Roberta , Zucconi Enrico Carlo , Gabutti Luca , Ogna Adam , Balestra Brenno , Valgimigli Marco
Published: April 2024

The Swiss Ticino regional pulmonary embolism response team (PERT) features direct access to various pharmacomechanical PE management options within a hub/spoke system, by integrating evidence, guidelines’ recommendations and personal experiences. This system involves a collaborative management of patients among the hospitals distributed throughout the region, which refer selected intermediate–high or high PE patients to a second-level hub center, located in Lugano at Cardiocentro Ticino, belonging to the Ente Ospedaliero Cantonale (EOC). The hub provides 24/7 catheterization laboratory activation for catheter-based intervention (CBI), surgical embolectomy and/or a mechanical support system such as extracorporeal membrane oxygenation (ECMO). The hub hosts PE patients after percutaneous or surgical intervention in two intensive care units, one specialized in cardiovascular anesthesiology, to be preferred for patients without relevant comorbidities or with hemodynamic instability and one specialized in post-surgical care, to be preferred for PE patients after trauma or surgery or with relevant comorbidities, such as cancer. From April 2022 to December 2023, a total of 65 patients were referred to the hub for CBI, including ultrasound-assisted catheter-directed thrombolysis (USAT) or large-bore aspiration intervention. No patient received ECMO or underwent surgical embolectomy.
Visual Field Tests: A Narrative Review of Different Perimetric Methods
Authors: Rai Bhim , Sabeti Faran , Carle Corinne , Maddess Ted
Published: April 2024

Visual field (VF) testing dates back to fifth century B.C. It plays a pivotal role in the diagnosis, management, and prognosis of retinal and neurological diseases. This review summarizes each of the different VF tests and perimetric methods, including the advantages and disadvantages and adherence to the desired standard diagnostic criteria. The review targets beginners and eye care professionals and includes history and evolution, qualitative and quantitative tests, and subjective and objective perimetric methods. VF testing methods have evolved in terms of technique, precision, user-friendliness, and accuracy. Consequently, some earlier perimetric techniques, often still effective, are not used or have been forgotten. Newer technologies may not always be advantageous because of higher costs, and they may not achieve the desired sensitivity and specificity. VF testing is most often used in glaucoma and neurological diseases, but new objective methods that also measure response latencies are emerging for the management of retinal diseases. Given the varied perimetric methods available, clinicians are advised to select appropriate methods to suit their needs and target disease and to decide on applying simple vs. complex tests or between using subjective and objective methods. Newer, rapid, non-contact, objective methods may provide improved patient satisfaction and allow for the testing of children and the infirm.
Revision of Failed Short Stems in Total Hip Arthroplasty
Authors: Migliorini Filippo , Coppola Francesco , D’Addona Alessio , Rosolani Marco , Della Rocca Federico
Published: April 2024

Background: The current literature lacks studies which evaluate the failure of short stems in total hip arthroplasty (THA). Therefore, the present clinical investigation reported our experience with the failure of short stems in THA, evaluating the causes of failure, survivorship, and the clinical outcomes of revision arthroplasty. Methods: The present study was performed according to the STROBE guidelines. This study was conducted at the Department of Orthopaedic Surgery of the Humanitas Clinical Institute, Milan, Italy, between 2017 and 2022. All patients who underwent revision surgery of a previously implanted THA using a short stem were prospectively included in the present study. Surgeries were performed with patients in lateral position, using a minimally invasive posterolateral approach. The outcomes of interest were to report information on the type and survivorship of implants used for the revision surgery and evaluate the clinical outcomes and the rate of complications. The following patient-reported outcome measures (PROMs) used for the clinical assessment were the Western Ontario McMaster Osteo-Arthritis Index (WOMAC) and related subscales of pain, stiffness, and function, and the visual analogue scale (VAS). Results: Data from 45 patients were retrieved. Of them, 31% (14 of 45 patients) were women. The mean age was 63.7 ± 13.9 years. The mean length of the implant survivorship was 6.2 ± 5.7 years. In total, 58% (26 of 45 patients) underwent revision of all components, 36% (16 of 45 patients) revised only the stem, and 1% (3 of 45 patients) received a two-stage revision. The mean length of the follow-up was 4.4 ± 1.5 years. The cup was revised in 58% (26 of 45) of patients. At 4.4 ± 1.5 years of follow-up, the WOMAC score was 3.5 ± 1.3 and the VAS was 1.2 ± 1.3. In total, 9% (4 of 45) of patients experienced minor complications. One patient used a walking aid because of reduced function. One patient evidenced muscular hypotrophy. Two patients experienced hip dislocations. All two dislocations were managed conservatively with repositioning in the emergency room under fluoroscopy. No patient needed additional revision surgery or experienced further dislocations. Conclusions: Revision surgery is effective and safe when a short stem THA fails. At approximately four years of follow-up, all patients were highly satisfied with their clinical outcomes. Despite the relatively high number (9%), complications were of a minor entity and were successfully managed conservatively.
Prognostic Significance of Lung Ultrasound for Heart Failure Patient Management in Primary Care: A Systematic Review
Authors: Panisello-Tafalla Anna , Haro-Montoya Marcos , Caballol-Angelats Rosa , Montelongo-Sol Maylin , Rodriguez-Carralero Yoenia , Lucas-Noll Jorgina , Clua-Espuny Josep Lluis
Published: April 2024

Background: Heart failure (HF) affects around 60 million individuals worldwide. The primary aim of this study was to evaluate the efficacy of lung ultrasound (LUS) in managing HF with the goal of reducing hospital readmission rates. Methods: A systematic search was conducted on PubMed, Embase, Google Scholar, Web of Science, and Scopus, covering clinical trials, meta-analyses, systematic reviews, and original articles published between 1 January 2019 and 31 December 2023, focusing on LUS for HF assessment in out-patient settings. There is a potential for bias as the effectiveness of interventions may vary depending on the individuals administering them. Results: The PRISMA method synthesized the findings. Out of 873 articles identified, 33 were selected: 19 articles focused on prognostic assessment of HF, 11 centred on multimodal diagnostic assessments, and two addressed therapeutic guidance for HF diagnosis. LUS demonstrates advantages in detecting subclinical congestion, which holds prognostic significance for readmission and mortality during out-patient follow-up post-hospital-discharge, especially in complex scenarios, but there is a lack of standardization. Conclusions: there are considerable uncertainties in their interpretation and monitoring changes. The need for an updated international consensus on the use of LUS seems obvious.
Telemetry System to Monitor Elastic Torque on Rolling Stand Spindles
Authors: Voronin Stanislav S. , Loginov Boris M. , Gasiyarova Olga A. , Evdokimov Sergey A. , Karandaev Alexander S. , Khramshin Vadim R.
Published: April 2024

This article outlines the relevance of building online telemetry systems for online monitoring of the technical conditions of rolling mill equipment. Electromechanical systems of the horizontal stand of the plate Mill 5000 are described, when operating in harsh conditions caused by the shock loading when workpieces enter the stand. It is noted that dynamic torque overloads, exceeding the rated motor torque by many-fold, cause the fatigue failure of spindle joints and breakage of rolls. In this regard, the development and implementation of systems for monitoring the elastic torque on spindles are extremely urgent. This issue has long been studied, but the references provide no information on the building principles and hardware composition of such systems. The use of strain gauges connected according to a balanced bridge circuit to measure the elastic torque is justified. This paper’s contribution is the proposed modular principle for building a telemetry monitoring system based on the analysis of known techniques for measuring and transmitting diagnostic data. The developed system structure is provided and the concept of data transfer and processing are explained. This article suggests the inductive power supply of a measuring unit mounted on a shaft without the use of batteries. A hardware structure was developed to be applied in a system for measuring, transmitting, and visualizing signals proportional to the elastic torque, manufactured on the basis of data measuring instruments by leading companies. The specifics of placement and connection of strain gauges are considered. The hardware providing a wireless power supply to the signal encoder and digital data transfer between the transmitter and receiver is described. The results of implementing the system on Mill 5000 are provided. The installation of a telemetry ring and a receiving head for the inductive power supply and data reception is shown. An experimental assessment of the elastic torques occurring when workpieces enter the cage was obtained by implementing a drive control algorithm which provided biting in the drive acceleration mode. The reliability of measuring the elastic torque with an error not exceeding ±5% and the reduction of dynamic loads on the spindle by 1.3–1.5 times due to the elimination of impacts from closing angular gaps in spindle joints was confirmed. This increases the service life of mechanical equipment and reduces the cost of eliminating the accident aftermath. The prospect of modifying the developed system into a cyber-physical system for monitoring the rolling mill’s mechatronic equipment conditions is shown.
Enhanced Energy Absorption with Bioinspired Composite Triply Periodic Minimal Surface Gyroid Lattices Fabricated via Fused Filament Fabrication (FFF)
Authors: Alemayehu Dawit Bogale , Todoh Masahiro
Published: April 2024

Bio-inspired gyroid triply periodic minimum surface (TPMS) lattice structures have been the focus of research in automotive engineering because they can absorb a lot of energy and have wider plateau ranges. The main challenge is determining the optimal energy absorption capacity and accurately capturing plastic plateau areas using finite element analysis (FEA). Using nTop’s Boolean subtraction method, this study combined walled TPMS gyroid structures with a normal TPMS gyroid lattice. This made a composite TPMS gyroid lattice (CTG) with relative densities ranging from 14% to 54%. Using ideaMaker 4.2.3 (3DRaise Pro 2) software and the fused deposition modeling (FDM) Raise3D Pro 2 3D printer to print polylactic acid (PLA) bioplastics in 1.75 mm filament made it possible to slice computer-aided design (CAD) models and fabricate 36 lattice samples precisely using a layer-by-layer technique. Shimadzu 100 kN testing equipment was utilized for the mechanical compression experiments. The finite element approach validates the results of mechanical compression testing. Further, a composite CTG was examined using a field emission scanning electron microscope (FE-SEM) before and after compression testing. The composite TPMS gyroid lattice showed potential as shock absorbers for vehicles with relative densities of 33%, 38%, and 54%. The Gibson–Ashby model showed that the composite TPMS gyroid lattice deformed mainly by bending, and the size effect was seen when the relative densities were less than 15%. The lattice’s relative density had a significant impact on its ability to absorb energy. The research also explored the use of these innovative foam-like composite TPMS gyroid lattices in high-speed crash box scenarios to potentially enhance vehicle safety and performance. The structures have tremendous potential to improve vehicle safety by acting as advanced shock absorbers, which are particularly effective at higher relative densities.
An Obstacle Avoidance Strategy for AUV Based on State-Tracking Collision Detection and Improved Artificial Potential Field
Authors: Li Yueming , Ma Yuhao , Cao Jian , Yin Changyi , Ma Xiangyi
Published: April 2024

This paper proposes a fusion algorithm based on state-tracking collision detection and the simulated annealing potential field (SCD-SAPF) to address the challenges of obstacle avoidance for autonomous underwater vehicles (AUVs) in dynamic environments. Navigating AUVs in complex underwater environments requires robust autonomous obstacle avoidance capabilities. The SCD-SAPF algorithm aims to accurately assess collision risks and efficiently plan avoidance trajectories. The algorithm introduces an SCD model for proactive collision risk assessment, predicting collision risks between AUVs and dynamic obstacles. Additionally, it proposes a simulated annealing (SA) algorithm to optimize trajectory planning in a simulated annealing potential field (SAPF), integrating the SCD model with the SAPF algorithm to guide AUVs in obstacle avoidance by generating optimal heading and velocity outputs. Extensive simulation experiments demonstrate the effectiveness and robustness of the algorithm in various dynamic scenarios, enabling the early avoidance of dynamic obstacles and outperforming traditional methods. This research provides an accurate collision risk assessment and efficient obstacle avoidance trajectory planning, offering an innovative approach to the field of underwater robotics and supporting the enhancement of AUV autonomy and reliability in practical applications.
Isolated Limb Perfusion and Immunotherapy in the Treatment of In-Transit Melanoma Metastases: Is It a Real Synergy?
Authors: Rastrelli Marco , Russano Francesco , Cavallin Francesco , Del Fiore Paolo , Pacilli Claudia , Di Prata Claudia , Rossi Carlo Riccardo , Vecchiato Antonella , Dall’Olmo Luigi , Mocellin Simone
Published: April 2024

Background: Isolated limb hyperthermic-antiblastic perfusion (ILP) was the most effective local treatment for advanced in-transit melanoma, but the advent of modern effective immunotherapy (IT), such as immune checkpoint inhibitors, has changed the treatment landscape. Methods: This study evaluated the role of the association between ILP and IT in the treatment of locally advanced unresectable melanoma, particularly in relation to modern systemic therapies. We analyzed 187 consecutive patients who were treated with ILP (melphalan or melphalan associated with TNF-alpha) for advanced melanoma at the Veneto Institute of Oncology of Padua (Italy) and the Padua University Hospital (Italy) between June 1989 and September 2021. Overall survival (OS), disease-specific survival (DSS), local disease-free survival (local DFS) and distant disease-free survival (distant DFS) were evaluated. Local toxicity was classified according to the Wieberdink scale and surgical complications according to the Clavien–Dindo classification. Response to locoregional therapy was evaluated during follow-up according to the RECIST 1.1 criteria (Response Evaluation Criteria in Solid Tumor). Results: A total of 99 patients were treated with ILP and 88 with IT + ILP. The overall response rate was 67% in both groups. At 36 months, OS was 43% in the ILP group and 61% in the ILP + IT group (p = 0.02); DSS was 43% in the ILP group and 64% in the ILP + IT group (p = 0.02); local DFS was the 37% in ILP group and 53% in the ILP + IT group (p = 0.04); and distant DFS was 33% in the ILP group and 35% in the ILP + IT group (p = 0.40). Adjusting for age and lymph node involvement, receiving ILP + IT was associated with improved OS (p = 0.01) and DSS (p = 0.007) but not local DFS (p = 0.13) and distant DFS (p = 0.21). Conclusions: Our findings confirm the synergy between ILP and IT. ILP remains a valuable loco-regional treatment option in the era of effective systemic treatments. Further studies are needed to establish the optimal combination of loco-regional and systemic treatments and address the best timing of this combination to obtain the highest local response rate.
Using Importance–Performance Analysis to Reveal Priorities for Multifunctional Landscape Optimization in Urban Parks
Authors: Xiao Xiaomin , Ye Qiaoru , Dong Xiaobin
Published: April 2024

In the context of urban renewal, residents have presented elevated expectations for the quality of urban parks, necessitating the optimization of parks’ multifunctional landscapes. Transforming residents’ preferences for landscape services into a prioritized index for multifunctional landscape renewal poses a significant challenge. This study addresses this research gap by integrating importance–performance analysis (IPA) with residents’ perception evaluations of landscape services. We establish an index system to evaluate perceptions of urban park landscape services. By employing the importance–performance analysis framework, we identify landscape service types that exhibit high importance but low satisfaction levels, thereby establishing priorities for multifunctional landscape renewal. Using Guangzhou’s urban parks as a case study, our findings reveal variations in users’ demands for different landscape services and differences in demand among various user groups for similar services. Users assign utmost importance to safety services while expressing the highest satisfaction with physical and mental health or microclimate regulation services. Significant disparities exist between middle-aged/elderly groups and young people regarding perceptions of social interaction, waste disposal, and sense of belonging services. Our results demonstrate that IPA analysis can elucidate priorities for multifunctional landscape renewal, facilitate public participation in improving urban park landscapes, and provide decision-making support for optimizing these landscapes.
Analysis of Spatial and Temporal Changes and Drivers of Urban Sprawl in Xinjiang Based on Integrated DMSP-OLS and NPP-VIIRS Data
Authors: Wang Luwei , Xu Wenzhe , Xue Xuan , Wang Haowei , Li Zhi , Wang Yang
Published: April 2024

The accelerated urbanization taking place across Xinjiang in recent years has vastly improved the quality of life for people living in the region. However, to achieve rational urban growth and sustainable regional development, a deeper understanding of the spatial and temporal patterns, spatial morphology, and driving factors of urban sprawl is crucial. Nighttime light (NTL) data provide a novel approach for studying the spatial and temporal changes in urban expansion. In this study, based on DMSP-OLS and NPP-VIIRS data, we analyze the spatiotemporal characteristics of urban changes using the standard deviation ellipse and employ the geographical detector to analyze the impact of natural environmental and socioeconomic factors on the dynamic rate of urban expansion. The results reveal the following. (1) The overall accuracy of urban area extraction is above 80%, and the urban area of Xinjiang has expanded about 9.1 times over the past 30 years. Further, the growth rate from 2007 to 2017 exceeds the growth rate from 1992 to 1997, with the center of gravity of urban development shifting to the southwest. (2) The 5a sliding average temperature and average annual precipitation in the study area in 1992–2022 are 6.08 °C and 169.72 mm, respectively, showing a decrease in the urbanization rate followed by an increase, due to a rise in temperature and precipitation levels. (3) By combining the results of geographical detector factor detection and interaction detection, precipitation is determined to be the main controlling factor, while air temperature and GDP are secondary factors. This study presents new findings on the correlation between urban spatial and temporal changes and climate in Xinjiang, thus providing a scientific reference for future research on urban expansion and natural environment evolution.
Online Assessment of Cross-Linguistic Similarity as a Measure of L2 Perceptual Categorization Accuracy
Authors: Cebrian Juli , Mora Joan C.
Published: April 2024

The effect of cross-linguistic similarity on the development of target-like categories in a second or additional language is widely attested. Research also shows that second-language speakers may access both their native and the second-language lexicons when processing second-language speech. Forty-three Catalan learners of English performed a perceptual assimilation task evaluating the perceived similarity between English and Catalan vowels and also participated in a visual world eye-tracking experiment investigating between-language lexical competition. The focus of the study was the English vowel contrasts /iː/-/ɪ/ and /æ/-/ʌ/. The perceptual task confirmed that English /iː/ and /æ/were perceptually closer to native Catalan categories than English /ɪ/ and /ʌ/. The results of the spoken word recognition task indicated that learners experienced greater competition from native words when the target words contained English /iː/ and /æ/, illustrating a close link between the two types of tasks. However, differences in the magnitude of cross-language lexical competition were found to be only weakly related to learners’ degree of perceived similarity to native categories at an individual level. We conclude that online tasks provide a potentially effective method of assessing cross-linguistic similarity without the concerns inherent to more traditional offline approaches.
No Object–Location Memory Improvement through Focal Transcranial Direct Current Stimulation over the Right Temporoparietal Cortex
Authors: Fromm Anna Elisabeth , Grittner Ulrike , Brodt Svenja , Flöel Agnes , Antonenko Daria
Published: April 2024

Remembering objects and their associated location (object–location memory; OLM), is a fundamental cognitive function, mediated by cortical and subcortical brain regions. Previously, the combination of OLM training and transcranial direct current stimulation (tDCS) suggested beneficial effects, but the evidence remains heterogeneous. Here, we applied focal tDCS over the right temporoparietal cortex in 52 participants during a two-day OLM training, with anodal tDCS (2 mA, 20 min) or sham (40 s) on the first day. The focal stimulation did not enhance OLM performance on either training day (stimulation effect: −0.09, 95%CI: [−0.19; 0.02], p = 0.08). Higher electric field magnitudes in the target region were not associated with individual performance benefits. Participants with content-related learning strategies showed slightly superior performance compared to participants with position-related strategies. Additionally, training gains were associated with individual verbal learning skills. Consequently, the lack of behavioral benefits through focal tDCS might be due to the involvement of different cognitive processes and brain regions, reflected by participant’s learning strategies. Future studies should evaluate whether other brain regions or memory-relevant networks may be involved in the modulation of object–location associations, investigating other target regions, and further exploring individualized stimulation parameters.
Materials for Heavy Metals Removal from Waters
Authors: Balintova Magdalena , Estokova Adriana
Published: April 2024

Although heavy metal ions are naturally present in the environment, their concentrations have significantly increased due to industrial activities [...]
Study on the Performance of a High-Speed Motor, Considering the Effect of Temperature on the Properties of High-Strength Non-Oriented Silicon Steel
Authors: Li Yulin , Yan Changhao , Wang Anqi , Li Jun , Zeng Lubin , Pei Ruilin
Published: April 2024

Considering the high-speed and high power density technical specifications of new energy vehicle motors, there is a growing demand for rotor strength as motor peak speeds reach 20,000 r/min and beyond. The utilization of non-oriented silicon steel with a high yield strength in rotors has emerged as a promising approach to increase motor speed. However, the magnetic and mechanical properties of high-strength silicon steel under variable temperature conditions have not been fully explored, particularly in regards to their impact on motor torque, efficiency, and speed. This manuscript investigates the behavior of high-strength silicon steel before and after annealing and at different temperatures, analyzing its influence on high-speed motor performance. The validity and feasibility of this study are confirmed through prototype testing, providing a comprehensive reference for engineering design.
Flexible and Compressible Nanostructure-Assembled Aramid Nanofiber/Silica Composites Aerogel
Authors: Zhang Chensi , Li Jiangtao , Jiang Junpeng , Hu Xiaoxia , Yang Shuo , Wang Kuan , Guo Anran , Du Haiyan
Published: April 2024

The Applications of silica aerogel are limited due to its brittleness and low strength. As a result, it is essential to strengthen and toughen it. Organic nanofibers are one of the preferred reinforcement materials. In this work, we designed and fabricated flexible and compressible nanostructure-assembled aramid nanofiber/silica composites aerogel (ANF/SiO2 aerogel) to improve the mechanical strength and flexibility of silica aerogel without compromising thermal insulation properties. The aramid nanofiber/silica composite aerogels were prepared by immersing the aramid nanofiber wet gel into the silica sol for a certain period of time followed by freeze drying without solvent replacement. The surface modifier 3-aminopropyltriethoxysilane (APTES) was used as a coupling agent to form chemical linkage between the ANF fiber and silica gel. It was observed that APTES can effectively drive the silica sol to infuse into ANF hydrogel, promoting the assembly of silica gel onto the fiber surface and a uniform distribution in the network of ANF. The compressive resilience, thermal stability, and thermal insulation properties of the composite aerogels were evaluated by inducing the silica aerogel into the ANF network to form a protective layer on the fiber and change the pore structure in the ANF network.
Evaluation of Physico-Chemical Characteristics of Cement Superplasticizer Based on Polymelamine Sulphonate
Authors: Judžentienė Asta , Zdaniauskienė Agnė , Ignatjev Ilja , Druteikienė Rūta
Published: April 2024

Cementitious materials are used to construct an engineered barrier in repositories for radioactive waste. The cement matrix may contain a variety of organic compounds, some of which are polymeric admixtures used as plasticizers. Superplasticizers (SPs) are highly effective organic cement additives for reducing water amount, increasing workability, homogeneity, plasticity and the non-segregation of mortars and grouts, improving mechanical properties and resistance to destructive environments. SPs in cement could have an impact on the long-term safety of the disposals of radioactive waste. These organic agents can leach from the cementitious matrix into groundwater and may affect the migration behaviour of radionuclides. The detailed chemical composition and other characteristics of the cement (CEM I 42.5 R, Sweden) used for the leaching experiments were evaluated. It contained mainly CaO (52.51 ± 1.37, %), and the surface area of the cement particles was 13.2 ± 1.3 m2/g. An insignificant increase in pH (from 12.6 ± 0.1 to 12.8 ± 0.1) was observed for the leachates over 10 days. A commercially available cement superplasticizer based on polymelamine sulphonate (PMS) Peramin SMF10 (Peramin AB, Sweden) was chosen for the research. The product’s chemical composition was analysed using wavelength-dispersive X-ray fluorescence (WD-XRF) spectroscopy, while other physico-chemical properties of the PMS superplasticizer were assessed by Raman spectroscopy and thermo-gravimetric analysis. In aqueous solutions and powders of PMS, the same most intensive features were observed at 774 cm−1 (ring out-of-plane deformation), 977 cm−1 (C-N-C bending, SO stretching) and 1055 cm−1 (C-N=C bending) in the Raman spectra. At up to 270 °C, the polymer was thermally stable. Raman and UV/Vis spectroscopies were used to assess the rate of the alkaline degradation of PMS superplasticizer in different aqueous solutions. No changes were observed in the hydrolytic solutions with any of the above analytical methods over a period of 3 years. The results obtained revealed a good thermal and chemical stability (in highly alkaline media, pH = 9.9–12.9) of the PMS polymer.
Adsorption of Heavy Metal Ions on Alginate-Based Magnetic Nanocomposite Adsorbent Beads
Authors: Russo Eleonora , Sgarbossa Paolo , Gelosa Simone , Copelli Sabrina , Sieni Elisabetta , Barozzi Marco
Published: April 2024

Graphene oxide and its magnetic nanoparticle-based composites are a well-known tool to remove heavy metals from wastewater. Unfortunately, one of the major issues in handling such small particles consists of their difficult removal from treated wastewater (even when their magnetic properties are exploited), due to their very small diameter. One possible way to overcome this problem is to embed them in a macroscopic biopolymer matrix, such as alginate or chitosan beads. In this way, the adsorbent becomes easier to handle and can be used to build, for example, a packed column, as in a traditional industrial adsorber. In this work, the removal performances of two different embedded magnetic nanocomposite adsorbents (MNAs) are discussed. The first type of MNA is based on ferrite magnetic nanoparticles (MNPs) generated by coprecipitation using iron(II/III) salts and ammonium hydroxide, while the second is based on a 2D material composed of MNP-decorated graphene oxide. Both MNAs were embedded in cross-linked alginate beads and used to treat artificial water contaminated with chromium(III), nickel(II), and copper(II) in different concentrations. The yield of removal and differences between MNAs and non-embedded magnetic nanomaterials are also discussed. From the results, it was found that the time to reach the adsorption equilibrium is higher when compared to that of the nanomaterials only, due to the lower surface/volume ratio of the beads, but the adsorption capacity is higher, due to the additional interaction with alginate.
Theoretical Study of the Magnetic and Optical Properties of Ion-Doped LiMPO4 (M = Fe, Ni, Co, Mn)
Authors: Apostolova Iliana N. , Apostolov Angel T. , Wesselinowa Julia Mihailowa
Published: April 2024

Using a microscopic model and Green’s function theory, we calculated the magnetization and band-gap energy in ion-doped LiMPO4 (LMPO), where M = Fe, Ni, Co, Mn. Ion doping, such as with Nb, Ti, or Al ions at the Li site, induces weak ferromagnetism in LiFePO4. Substituting Li with ions of a smaller radius, such as Nb, Ti, or Al, creates compressive strain, resulting in increased exchange interaction constants and a decreased band-gap energy, Eg, in the doped material. Notably, Nb ion doping at the Fe site leads to a more pronounced decrease in Eg compared to doping at the Li site, potentially enhancing conductivity. Similar trends in Eg reduction are observed across other LMPO4 compounds. Conversely, substituting ions with a larger ionic radius than Fe, such as Zn and Cd, causes an increase in Eg.
Adsorption of Co2+ and Cr3+ in Industrial Wastewater by Magnesium Silicate Nanomaterials
Authors: Bao Jing , Feng Yongjun , Pan Yong , Jiang Juncheng
Published: April 2024

In this paper, two flower-like magnesium silicate nanomaterials were prepared. These and another two commercial magnesium silicate materials were characterized using a scanning electron microscope, the N2 adsorption–desorption method, and other methods. The structure–activity relationship between the adsorption performance of these four magnesium silicate materials and their specific surface area, pore size distribution, and pore structure was compared. The results showed that the 3-FMS modified by sodium dodecyl sulfonate (SDS) had the largest specific surface area and pore size, the best adsorption performance, and the largest experimental equilibrium adsorption capacity (qe,exp) for Co2+, reaching 190.01 mg/g, and Cr3+, reaching 208.89 mg/g. The adsorption behavior of the four materials for Co2+ and Cr3+ both fitted the pseudo-second-order kinetic model and Langmuir adsorption model, indicating that chemical monolayer uniform adsorption was the dominant adsorption process. Among them, the theoretical adsorption capacity (qm) of 3-FMS was the highest, reaching 207.62 mg/g for Co2+ and 230.85 mg/g for Cr3+. Through further research, it was found that the four materials mainly removed Co2+ and Cr3+ through electrostatic adsorption, surface metal ions (Mg2+), and acidic groups (-OH and -SO3H) exchanging with ions in solution. The adsorption performance of two self-made flower-like magnesium silicate materials for Co2+ and Cr3+ was superior to that of two commercial magnesium silicates.
Analysis of the Effect of Surface Preparation of Aluminum Alloy Sheets on the Load-Bearing Capacity and Failure Energy of an Epoxy-Bonded Adhesive Joint
Authors: Ciecińska Barbara , Mucha Jacek , Bąk Łukasz
Published: April 2024

Surface preparation is an important step in adhesive technology. A variety of abrasive, chemical, or concentrated energy source treatments are used. The effects of these treatments vary due to the variety of factors affecting the final strength of bonded joints. This paper presents the results of an experimental study conducted to determine the feasibility of using fiber laser surface treatments in place of technologically and environmentally cumbersome methods. The effect of surface modification was studied on three materials: aluminum EN AW-1050A and aluminum alloys EN AW-2024 and EN AW-5083. For comparison purposes, joints were made with sandblasted and laser-textured surfaces and those rolled as reference samples for the selected overlap variant, glued with epoxy adhesive. The joints were made with an overlap of 8, 10, 12.5, 14, and 16 mm, and these tests made it possible to demonstrate laser processing as a useful technique to reduce the size of the overlap and achieve even higher load-bearing capacity of the joint compared to sandblasting. A comparative analysis was also carried out for the failure force of the adhesive bond and the failure energy. The results show the efficiency and desirability of using lasers in bonding, allowing us to reduce harmful technologies and reduce the weight of the bonded structure.
Preparation of Wheat Straw Hot-Pressed Board through Coupled Dilute Acid Pretreatment and Surface Modification
Authors: Wang Jianing , Zhang Libo , Xiao Yepeng , Fan Qinzhen , Yang Chong , Deng Yiqiang , Lu Hao , Cheng Lihua
Published: April 2024

The production of wheat straw waste board materials encounters challenges, including inadequate inherent adhesiveness and the utilization of environmentally harmful adhesives. Employing a hot-pressed method for converting wheat straw into board materials represents a positive stride towards the resourceful utilization of agricultural wastes. This study primarily focuses on examining the influence of hot-pressing process conditions on the mechanical properties of wheat straw board materials pretreated with dilute acid. Additionally, it assesses the necessity of dilute acid treatment and optimizes the hot-pressing conditions to achieve optimal results at 15 MPa, 2 h, and 160 °C. Furthermore, a comprehensive process is developed for preparing wheat straw hot-pressed board materials by combining dilute acid pretreatment with surface modification treatments, such as glutaraldehyde, citric acid, and rosin. Finally, a thorough characterization of the mechanical properties of the prepared board materials is conducted. The results indicate a substantial improvement in tensile strength across all modified wheat straw board materials compared to untreated ones. Notably, boards treated with glutaraldehyde exhibited the most significant enhancement, achieving a tensile strength of 463 kPa, bending strength of 833 kPa, and a water absorption rate of 14.14%. This study demonstrates that combining dilute acid pretreatment with surface modification treatments effectively enhances the performance of wheat straw board materials, offering a sustainable alternative to traditional wood-based board materials.
The Influence of Surface Texture of Elements Made of PA6-Based Composites on Anti-Graffiti Effect of Paint Coating
Authors: Mróz Adrian , Szymański Maciej , Koch Paweł , Pawlicki Marek , Meller Artur , Przekop Robert Edward
Published: April 2024

The aim of the work was to investigate the influence of the surface texture of composite based on PA6, intended for wet painting, on the stability of the colour and gloss parameters. The stability of the paint coating was required to be maintained despite exposure to mechanical stress resulting from attempts to manually remove graffiti stains. The study examined the influence of surface texture on the effectiveness of cleaning. In the case of painted surfaces from which graffiti stains were effectively removed, the roughness, colour parameters and gloss of the paint coating were measured. During the research, it was found that roughness after painting decreased to the value of Ra < 2.00 µm meets aesthetic expectations and at the same time ensures the effective removal of graffiti stains. For this surface, there were no negative effects of the mechanical impact on the textures or quality parameters of the coating as a result of manual graffiti removal. As a result of the conducted research, the recommended maximum values of roughness and textures of the surfaces to be painted were determined in order to ensure a sufficiently low amount of work necessary to effectively remove traces of graffiti.
Investigation of Crystallization Growth Characteristics of Mg(OH)2 Crystals under Unconstrained Conditions
Authors: Lv Yunqing , Bai Limei , Ma Yuxin , Zhao Liucheng
Published: April 2024

Utilizing MgO as the precursor and deionized water as the solvent, this study synthesized nanoparticles of Mg(OH)2 via hydrothermal methods, aiming to control its purity, particle size, and morphology by understanding its growth under non-uniform nucleation. Characterization of crystal morphology and structure was conducted through scanning electron microscopy and X-ray diffraction, while laser particle size detection assessed the secondary particle size distribution. The study focused on how MgO’s hydrothermal process conditions influence Mg(OH)2 crystal growth, particularly through ion concentration and release rate adjustments to direct crystal growth facets. These adjustments shifted the dominant growth plane, enhancing the peak intensity ratio I001/I101 from 1.03 to 2.14, thereby reducing surface polarity and secondary aggregation of crystals. The study of the physicochemical properties of the same sample at different times revealed the pattern of crystal dissolution and recrystallization. A 2 h hydrothermal reaction notably altered the particle size distribution, with a decrease in particles sized 0.2~0.4 μm and an increase in those sized 0.4~0.6 μm, alongside new particles over 1 μm, indicating a shift toward uniformity through dissolution and recrystallization. Optimal conditions (6% magnesium oxide concentration, 160 °C, 2 h) led to the synthesis of highly dispersed, uniformly sized magnesium hydroxide, showcasing a simple, eco-friendly, and high-yield process.