bluuebunny/crossref_metadata_2025 huggingface dataset:
Interactive Effects of Warming and Pollutants on Marine and Freshwater Invertebrates
Authors: Dinh Khuong V. , Konestabo Heidi Sjursen , Borgå Katrine , Hylland Ketil , Macaulay Samuel J. , Jackson Michelle C. , Verheyen Julie , Stoks Robby
Published: December 2022

Purpose of Review

Global warming and pollution are among the five major causes of global biodiversity loss, particularly in aquatic invertebrates which are highly diverse but understudied. In this review, we highlight advancements in current environmental studies investigating the interactive effects between warming and contaminants in freshwater and marine invertebrates. We not only focused on temperate regions but also synthesized information on the less studied Arctic/Antarctic and tropical regions.

Recent Findings

In general, the same combination of warming and contaminants may result in either additive or non-additive interactive effects depending on taxa, the response variable, life stage, genotype, exposure level, duration and order of exposure, and the number of exposed generations. For traditional contaminants such as metals and pesticides, combined effects with warming at the individual level were generally synergistic. Growing evidence suggests that multigenerational exposure can shift the interaction between warming and contaminants toward antagonism, while contemporary evolution may change the interaction type.

Our synthesis highlights the importance of temporal aspects in shaping interaction type, including order of exposure, ontogenetic effects, transgenerational effects, and evolution. The combination of laboratory experiments (to advance mechanistic understanding) and outdoor mesocosm studies or field observations (to increase realism) is needed to obtain comprehensive assessments of interactive effects of warming and pollutants from genes to ecosystems.
Just translation? A socioecological justice lens on EU environmental governance and urban mobility transitions
Authors: Stockmann Nils , Graf Antonia
Published: December 2022

EU environmental policies such as the Ambient Air Quality Directive 2008/50 are highly relevant in this age of the looming climate crisis and interconnected sustainable transitions. However, implementation efforts such as low-emission zones, road pricing, and driving bans affect citizens in heterogenous situations and in ways that evoke questions of socioecological justice. This has resulted in an increasingly polarized reluctance to respective governance across Europe. The EU policy implementation literature often omits these less clearly operationalized norms that EU policies transport and pays little attention to how stakeholders in cities discursively and practically translate EU directives. Constructivist norm research underlines the importance of ‘localizing’ by highlighting that justice does matter for norm translation. The environmental justice concept has, however, not been systematically introduced and referenced in the norm research literature. This article offers a heuristic to address this research gap by combining a translation perspective from International Relations norm research with an environmental justice lens. Following the journey of the Air Quality Directive 2008/50, we ask how urban implementation configures the Directive’s environmental justice dimension and why this is important for effective and sustainable EU governance. Empirically, we focus on action plans and participation processes regarding Directive 2008/50 in Brussels, Glasgow, and Hamburg. As a result, we show that EU environmental governance unfolds at the local level as a dynamic contestation of different distributive justice claims that then translate into concrete policies. The analysis indicates that those policies must procedurally integrate local knowledge and identity formation to enable comprehensively just sustainable transformations.
Traffic flow prediction using bi-directional gated recurrent unit method
Authors: Wang Shengyou , Shao Chunfu , Zhang Jie , Zheng Yan , Meng Meng
Published: December 2022

Traffic flow prediction plays an important role in intelligent transportation systems. To accurately capture the complex non-linear temporal characteristics of traffic flow, this paper adopts a Bi-directional Gated Recurrent Unit (Bi-GRU) model in traffic flow prediction. Compared to Gated Recurrent Unit (GRU), which can memorize information from the previous sequence, this model can memorize the traffic flow information in both previous and subsequent sequence. To demonstrate the model’s performance, a set of real case data at 1-hour intervals from 5 working days was used, wherein the dataset was separated into training and validation. To improve data quality, an augmented dickey-fuller unit root test and differential processing were performed before model training. Four benchmark models were used, including the Autoregressive Integrated Moving Average (ARIMA), Long Short-Term Memory (LSTM), Bidirectional Long Short-Term Memory (Bi-LSTM), and GRU. The prediction results show the superior performance of Bi-GRU. The Root Mean Square Error (RMSE), Mean Absolute Percentage Error (MAPE), and Mean Absolute Error (MAE) of the Bi-GRU model are 30.38, 9.88%, and 23.35, respectively. The prediction accuracy of LSTM, Bi-LSTM, GRU, and Bi-GRU, which belong to deep learning methods, is significantly higher than that of the traditional ARIMA model. The MAPE difference of Bi-GRU and GRU is 0.48% which is a small prediction error value. The results show that the prediction accuracy of the peak period is higher than that of the low peak. The Bi-GRU model has a certain lag on traffic flow prediction.
The Greeks and Their Histories
Authors: Gehrke Hans-Joachim , Grethlein Jonas
Published: December 2022

In this concise but stimulating book on history and Greek culture, Hans-Joachim Gehrke continues to refine his work on 'intentional history', which he defines as a history in the self-understanding of social groups and communities – connected to a corresponding understanding of the other – which is important, even essential, for the collective identity, social cohesion, political behaviour and the cultural orientation of such units. In a series of four chapters Gehrke illustrates how Greeks' histories were consciously employed to help shape political and social realities. In particular, he argues that poets were initially the masters of the past and that this dominance of the aesthetic in the view of the past led to an indissoluble amalgamation of myth and history and lasting tension between poetry and truth in the genre of historiography. The book reveals a more sophisticated picture of Greek historiography, its intellectual foundations, and its wider social-political contexts.
Recognition and the Self in Hegel's Phenomenology of Spirit
Authors: Brownlee Timothy L.
Published: December 2022

Hegel's Phenomenology of Spirit is famed for its account of the problem of recognition. Yet while readers agree about the importance of its influential accounts of the struggle to the death and the master/slave relation in developing that problem, there is no consensus regarding what sorts of relations among subjects would count as successful forms of recognition. Timothy Brownlee articulates the essential connections between Hegel's concepts of recognition and the self, and presents a novel interpretation of the Phenomenology that traces the emergence of actual relations of reciprocal recognition through the work as a whole. He focuses on the distinctive social constitution conception of the self that Hegel develops in his account of 'spirit,' and demonstrates that the primary significance of recognition lies in its contribution to self-knowledge. His book will be valuable for scholars and students interested in Hegel, German Idealism, and philosophical conceptions of recognition.
Zero Tolerance
Authors: Potter Philip B. K. , Wang Chen
Published: December 2022

China's mistreatment of its Uyghur minority has drawn international condemnation and sanctions. The repression gripping Xinjiang is also hugely costly to China in Renminbi, personnel, and stifled economic productivity. Despite this, the Chinese Communist Party persists in its policies. Why? Drawing on extensive original data, Potter and Wang demonstrate insecurities about the stability of the regime and its claim to legitimacy motivate Chinese policies. These perceived threats to core interests drive the ferocity of the official response to Uyghur nationalism. The result is harsh repression, sophisticated media control, and selective international military cooperation. China's growing economic and military power means that the country's policies in Xinjiang and Central Asia have global implications. Zero Tolerance sheds light on this problem, informing policymakers, scholars, and students about an emerging global hotspot destined to play a central role in international politics in years to come.
Bloomsbury, Beasts and British Modernist Literature
Authors: Ryan Derek
Published: December 2022

Bloomsbury, Beasts and British Modernist Literature reveals how the Bloomsbury group's fascination with beasts – from pests to pets, tiny insects to big game – became an integral part of their critique of modernity and conceptualisation of more-than-human worlds. Through a series of close readings, it argues that for Leonard Woolf, David Garnett, Virginia Woolf and E. M. Forster, profound shifts in interspecies relations were intimately connected to questions of imperialism, race, gender, sexuality and technology. Whether in their hunting narratives, zoo fictions, canine biographies or (un)entomological aesthetics, these writers repeatedly test the boundaries between, and imagine transformations of, human and nonhuman by insisting that we attend to the material contexts in which they meet. In demonstrating this, the book enrichens our understanding of British modernism while intervening in debates on the cultural significance of animality from the turn of the twentieth century to the Second World War.
Liberalism after the Revolution
Authors: Sotiropoulos Michalis
Published: December 2022

How is a new state built? To what ideas, concepts and practices do authorities turn to produce and legitimise its legal and political system? And what if the state emerged through revolution, and sought to obliterate the legacy of the empire which proceeded it? This book addresses these questions by looking at nineteenth-century Greek liberalism and the ways in which it engaged in reforms in the Greek state after independence from the Ottomans (ca. 1830-1880). Liberalism after the Revolution offers an original perspective on this dynamic period in European history, and challenges the assumptions of Western-centric histories of nineteenth-century liberalism, and its relationship with the state. Michalis Sotiropoulos shows that, in this European periphery, liberals did not just transform liberalism into a practical mode of statecraft, they preserved liberalism's radical edge at a time when it was losing its appeal elsewhere in Europe.
Beyond Technology: Pottery Reveals Translocal Social Relations at a Bell Beaker Monumental Site in Central Europe
Authors: Gašpar Adam , Petřík Jan , Fojtík Pavel , Tsoupra Anna , Mir-Makhamad Basira , Cardoso Ana , Beltrame Massimo , Mirão José , Schiavon Nick , Kolář Jan
Published: December 2022

The Bell Beaker site near Brodek u Prostějova (Czechia) has yielded remains of a large timber construction accompanied by four symmetrical ritual deposits with numerous artefacts, including more than fifty ceramic vessels. Their decoration consists of incised patterns, in nineteen cases with preserved white inlaid incrustations. To investigate the social relations at this extraordinary site, a multi-analytical and micro-destructive approach was employed to determine the provenance and technology of the pottery and the composition of the white incrustations. The results indicate various origins for the pottery within the region and the presence of extra-regional fabrics and graphitic temper. The main raw materials for the white inlays were calcium carbonate (calcite), hydroxyapatite (bone), and bright clay. The mixing of decorative motifs and the variation in the shape and size of the beakers suggest unique manufacturing processes. These results lend support to the monumental site of Brodek serving as a ritual place for several communities from both local and wider areas.
Stochastic parameterization of column physics using generative adversarial networks
Authors: Nadiga Balasubramanya T. , Sun Xiaoming , Nash Cody
Published: December 2022

We demonstrate the use of a probabilistic machine-learning technique to develop stochastic parameterizations of atmospheric column physics. After suitable preprocessing of NASA’s Modern-Era Retrospective analysis for Research and Applications, version 2 (MERRA2) data to minimize the effects of high-frequency, high-wavenumber component of MERRA2 estimate of vertical velocity, we use generative adversarial networks to learn the probability distribution of vertical profiles of diabatic sources conditioned on vertical profiles of temperature and humidity. This may be viewed as an improvement over previous similar but deterministic approaches that seek to alleviate both, shortcomings of human-designed physics parameterizations, and the computational demand of the “physics” step in climate models.
British Liberalism and the French Invasion of Mexico
Authors: Middleton Alex
Published: December 2022

Napoleon III's 1860s intervention in Mexico mystified some British observers. For many others, however, it raised urgent questions about the duties of European civilization and the future of global order. This article argues that the affair forced attitudes toward other European countries' overseas imperial projects into sharp political focus, and that in doing so it revealed incipient shifts in the center of gravity of Victorian liberalism. France's Second Mexican Empire split opinion in the Liberal Party and press, throwing light on wider disputes about the parameters of legitimate imperial intervention, the reach of the principles of nationality and self-determination, the political needs of disordered multiracial polities in less-developed parts of the world, and Europe's proper relations with Spanish America. But most Liberals who engaged with the enterprise condemned it, a fact that lays bare a changing balance of power between what historians have called “liberal imperial” and noninterventionist arguments in the 1860s. The failure of the intervention, moreover, did much to affirm powerful partisan narratives about French politics, which helped to buttress the electoral ascendancy of the Liberal Party.
Machine-learned control-oriented flow estimation for multi-actuator multi-sensor systems exemplified for the fluidic pinball
Authors: Li Songqi , Li Wenpeng , Noack Bernd R.
Published: December 2022

We propose the first machine-learned control-oriented flow estimation for multiple-input, multiple-output plants. The starting point is constant actuation with open-loop actuation commands leading to a database with simultaneously recorded actuation commands, sensor signals and flow fields. A key enabler is an estimator input vector comprising sensor signals and actuation commands. The mapping from the sensor signals and actuation commands to the flow fields is realized in an analytically simple, data-centric and general nonlinear approach. The analytically simple estimator generalizes linear stochastic estimation for actuation commands. The data-centric approach yields flow fields from estimator inputs by interpolating from the database – similar to Loiseau, Noack & Brunton (J. Fluid Mech., vol. 844, 2018, pp. 459–490) for unforced flow. The interpolation is performed with$k$nearest neighbours ($k$NN). The general global nonlinear mapping from inputs to flow fields is obtained from a deep neural network (DNN) via an iterative training approach. The estimator comparison is performed for the fluidic pinball plant, which is a multiple-input, multiple-output wake control benchmark (Denget al.,J. Fluid Mech., vol. 884, 2020, A37) featuring rich dynamics under steady controls. We conclude that the machine learning methods clearly outperform the linear model. The performance of$k$NN and DNN estimators are comparable for periodic dynamics. Yet the DNN performs consistently better when the flow is chaotic. Moreover, a thorough comparison regarding the complexity, computational cost and prediction accuracy is presented to demonstrate the relative merits of each estimator. The proposed method can be generalized for closed-loop flow control plants.
Effects of thermophoresis on high-pressure binary-species boundary layers with uniform and non-uniform compositions
Authors: Toki Takahiko , Bellan Josette
Published: December 2022

Direct numerical simulations of high-pressure binary-species temporal boundary layers are performed to investigate the flow physics for three situations: (1) uniform and equal composition, (2) uniform but unequal compositions and (3) non-uniform composition. Both colder- and hotter-wall situations compared with the free stream are simulated. The working fluid is a nitrogen/methane mixture. The analysis is performed at a case-specific self-similar state. Even when the initial composition is uniform, the methane mean mass fraction decreases near the colder wall, whereas it increases near the hotter wall and the mass fraction fluctuates in the entire boundary layer. Analysis of the species-mass diffusion balance and flow structures reveal that both mass-fraction variation and fluctuations are induced by the Soret effect. When the initial composition is non-uniform and the wall is colder, the methane mean mass fraction monotonically increases from the wall akin to its initial profile. However, when the wall is hotter the mean mass fraction decreases near the wall in contrast to its initial profile, a fact traced through the species-mass diffusion balance to the Soret effect being large and enriching methane near the wall. In contrast, the direction of the Soret flux is opposite for the colder wall, thus keeping the methane concentration small. Although the initial magnitude of the difference between the wall and free-stream temperature is the same in all cases, the situation is not symmetric between colder- and hotter-wall cases; the flow structure exhibits much smaller scales when the wall is hotter than when the wall is colder.
Controlled stabilization of rotating toroidal drops in viscous linear flow
Authors: Malik Sumit , Lavrenteva Olga M. , Idan Moshe , Nir Avinoam
Published: December 2022

Toroidal drops, embedded in viscous flow, have a large range of stationary shapes that are challenging to compute numerically due to their inherent instability. When both the drop and the outer fluid are Newtonian liquids, the only reported cases of such stable configurations are of highly expanded drops rotating in an axisymmetrical extensional flow. In this study, we propose a method for stabilizing the stationary shapes of inherently unstable rotating toroidal drops, embedded in extensional or biextensional flow, by subjecting the system to feedback control stabilization. The proposed controller is designed using a two-state dynamic model of the system and is tested on a high-order nonlinear dynamic model of the drop deformation. It is demonstrated that, through this simplified feedback-control-centred approach, an extended collection of stabilized stationary solutions is generated, which spans the range from highly expanded drops to almost collapsed ones. In the latter region, that was never obtained in previous studies, multiplicity of solutions is identified. Furthermore, our method is more accurate and more efficient compared with the previously used ones.
High-order strongly nonlinear long wave approximation and solitary wave solution. Part 2. Internal waves
Authors: Choi Wooyoung
Published: December 2022

A strongly nonlinear long-wave approximation is adopted to obtain a high-order model for large-amplitude long internal waves in a two-layer system by assuming the water depth is much smaller than the typical wavelength. When truncated at the first order, the model can be reduced to the regularized strongly nonlinear model of Choiet al.(J. Fluid Mech., vol. 629, 2009, pp. 73–85), which lessens the Kelvin–Helmholtz instability excited by the tangential velocity jump across the interface in the inviscid Miyata–Choi–Camassa (MCC) equations. Using the second-order model, the next-order correction to the internal solitary wave solution of the MCC equations is found and its validity is examined with the Euler solution in terms of the wave profile, the effective wavelength and the velocity profile. It is shown that the correction greatly improves the comparison with the Euler solution for the whole range of wave amplitudes and no further correction is necessary for practical applications. Based on a local stability analysis, the region of stability for the second-order long-wave model is identified in the physical parameter space so that the efficient numerical scheme developed for the first-order model can be used for the second-order model.
Trauma and Turnout: The Political Consequences of Traumatic Events
Authors: MARSH WAYDE Z. C.
Published: December 2022

How do traumatic experiences shape individuals’ political behavior? Political scientists have investigated the behavioral changes caused by natural disasters and terrorist attacks, but no work to date has investigated the political consequences of such events using the framework of psychological trauma. In this study, I develop a theory of posttraumatic political response that explains how traumatic events influence voter turnout. To test this theory, I identify the effects of three different types of traumatic events: Black church arson attacks, mass shootings, and natural disasters. I find that a traumatic event decreases turnout in the next presidential election by 0.5–3.7 percentage points, but Black social identity conditions this effect—church arsons and Hurricane Katrina mobilize Black voters. Finally, I find that closer temporal proximity to an election increases the likelihood of a mobilizing effect.
Sanctuary after Asylum: Addressing a Gap in the Political Theory of Refuge
Authors: RITHOLTZ SAMUEL , BUXTON REBECCA
Published: December 2022

This research note argues that political theorists of refuge ought to consider the experiences of refugeesafterthey have received asylum in the Global North. Currently, much of the literature concerning the duties of states toward refugees implicitly adopts a blanket approach, rather than considering how varied identities may affect the remedies available to displaced people. Given the prevalence of racism, xenophobia, and homophobia in the Global North, and the growing norm of dissident persecution in foreign territory, protection is not guaranteed after either territorial or legal admission. This research note considers the case of LGBTQ refugees in order to demonstrate the analytical potential of more inclusive and diverse normative approaches. Taking the origin and extension of harm seriously requires a conceptualization of sanctuaryafterasylum that accurately reflects the experiences of the displaced. In doing so, questions arise regarding the nature and efficacy of territorial asylum.
Inferring ecological connectivity between populations of Opsanus beta (Goode & Bean, 1880) from the southern Gulf of Mexico and the South-western Atlantic coast
Authors: Carvalho Barbara Maichak de , Pérez José Antônio Martínez , Aguilar-Perera Alfonso , Noh Quiñones Virginia , Tomás Acácio Ribeiro Gomes , Vitule Jean , Volpedo Alejandra
Published: December 2022

Otoliths are an excellent tool in studies on ecological connectivity of fish species populations. Opsanus beta is an invasive species introduced on the Brazilian coast, but not native from the Gulf of Mexico. The present study aimed to compare the otolith contours of specimens collected in Mexico (Celestún, CEL) and in two Brazilian estuaries (Santos Bay, STB, and Paranaguá Estuarine Complex, PEC). In the laboratory, 99 otoliths were extracted, photographed and compared using wavelet analysis. The otolith contours varied between sites (39 from CEL, 26 from STB and 34 from PEC). The linear discriminant analysis correctly reclassified 87.9% of otoliths by sites, with the best reclassifications in the CEL (97.36%), followed by PEC (88.23%) and SBT (73.07%). MANOVA showed significant differences in otolith contours between sites (F = 5.37; P < 0.005). The otolith contour from CEL was significantly different from those from the PEC and SBT. However, the otolith contour of the two Brazilian estuaries did not significantly differ among them (MANOVA, P > 0.005). Our results indicate O. beta populations on the Brazilian coast are connected, and probably isolated from the Mexican population.
The Healing of Maseko
Authors: Adelakun Abimbola A.
Published: December 2022

Enforced restriction of movement and social distancing regulations during the pandemic pushed a Nigerian-based church with global membership to innovate liveness without co-presence. The church purportedly transcended time-space limits in miracle performances during their Distance Is Not a Barrier digital sessions.
Metered Togetherness
Authors: Kimmel Anna Jayne , Martin Diana Damian , Warren Asher
Published: December 2022

Moving beyond speculation on immediate and mediated interpretations of presence that saturate our field, we drift toward new orientations regarding presence that capture a metered togetherness: a disjuncted assembly emerging from both localized and networked logistics. Presence is not always signaled by the coterminous junction of shared time and space, but as the multiple trajectories that emerge in its wake.
Evaluation of perceived depression, anxiety, stress levels and emotional eating behaviours and their predictors among adults during the COVID-19 pandemic
Authors: Kaner Gülşah , Yurtdaş-Depboylu Gamze , Çalık Gamze , Yalçın Tuba , Nalçakan Tutku
Published: December 2022

Objective:

This study aimed to (1) evaluate the prevalence and predictors of perceived depression, anxiety, stress (DAS) levels and emotional eating behaviours and (2) determine the correlations between DAS levels and emotional eating behaviours during the pandemic.

Design:

An online cross-sectional study included questions about demographic and anthropometric characteristics, dietary habits, Emotional Appetite Questionnaire (EMAQ) and Depression Anxiety Stress Scales. The snowball sampling method was used.

Setting:

Türkiye.

Participants:

The study population was 2002 adults aged ≥18 years.

Result:

The mean age was 27·1 ± 9·52 years (72·1 % females and 27·9 % males). The prevalence of moderate to severe DAS was reported as 27·8 %, 30·5 % and 30·7 %, respectively. Skipping meals (OR = 1·32, 95 % CI (1·14, 1·49)) was associated with depression. Weight gain (OR = 1·43, 95 % CI (1·19, 1·66); OR = 1·30, 95 % CI (1·14, 1·49); OR = 1·39, 95 % CI (1·14, 1·64)), weight loss (OR = 1·45, 95 % CI (1·20, 1·70); OR = 1·37, 95 % CI (1·11, 1·62); OR = 1·46, 95 % CI (1·20, 1·72)), exercising at least 150 min/week (OR = 0·64, 95 % CI (0·46, 0·83); OR = 0·73, 95 % CI (0·55, 0·92); OR = 0·83, 95 % CI (0·63, 1·02)), and maintaining an adequate and balanced diet (OR = 0·52, 95 % CI (0·33, 0·71); OR = 0·53, 95 % CI (0·34, 0·73); OR = 0·63, 95 % CI (-0·15, 0·35)) were associated with DAS, respectively. BMI (r= 0·169,P< 0·001), weight (r= 0·152,P< 0·001), number of snacks (r= 0·102,P= 0·011), depression (r= 0·060,P= 0·007), anxiety (r= 0·061,P= 0·006) and stress (r= 0·073,P= 0·001) levels were positively correlated with EMAQ-negative scores.

Conclusion:

Approximately one out of every three participants reported moderate to severe DAS levels. Emotional eating was significantly correlated with perceived DAS. The predictors obtained in the study suggest that a healthy diet and lifestyle behaviours are part of psychological well-being and emotional eating.
Formulating psychosis: a thematic analysis of CBTp trainees’ experiences
Authors: Newman-Taylor Katherine , Wood Rachael , Ellis Abigail , Isham Louise
Published: December 2022

The NICE guidance states that cognitive behavioural therapy (CBT) should now be offered to everyone with psychosis in the UK. This has rightly resulted in an increased demand for adherent therapy from qualified clinicians. Individualised formulation is a key component of CBT for psychosis, yet many trainees struggle to make sense of and apply the theoretical models on which these are based. This study explored trainee and recently qualified therapists’ experience of formulating CBT for psychosis, to help us understand how best to guide training and clinical practice. We ran focus groups with trainees who were completing, or had recently completed, postgraduate training in CBT for psychosis. We then analysed verbatim transcripts of the semi-structured interviews. and completed a thematic analysis of the data using inductive open coding. Three over-arching themes were generated: (1) purpose of formulation, (2) formulation in practice, and (3) (reflection on) learning to formulate. Training programmes and clinical supervisors should focus on fostering trainees’ and newly qualified therapists’ ability to develop simple, targeted formulations. These will draw on maintenance and developmental models of psychosis, depending on the person’s needs and goals. Opportunities for procedural learning are likely to improve skilful formulation, and use as the basis for therapeutic change.

Key learning aims

(1)

CBT for psychosis is best guided by individualised formulation.

(2)

The range and complexity of current theoretical models is challenging.

(3)

A qualitative analysis of trainee and recently qualified therapists’ experiences highlights means of facilitating understanding and application of these models.
Cenozoic Proxy Constraints on Earth System Sensitivity to Greenhouse Gases
Authors: Ring S. J. , Mutz S. G. , Ehlers T. A.
Published: December 2022

The long‐term extent of the Earth system response to anthropogenic interference remains uncertain. However, the geologic record offers insights into this problem as Earth has previously cycled between warm and cold intervals during the Phanerozoic. We present an updated compilation of surface temperature proxies for several key time intervals to reconstruct global temperature changes during the Cenozoic. Our data synthesis indicates that Earth’s surface slowly cooled by ca. 9°C during the early Paleogene to late Neogene and that continent‐scale ice sheets developed after global temperature dropped to less than 10°C above preindustrial conditions. Slow cooling contrasts with the steep decrease in combined radiative forcing from past CO2 concentrations, solar luminosity, and ocean area, which was close to preindustrial levels even as Earth remained in a much warmer state. From this, we infer that the Earth system was less sensitive to greenhouse gas forcing for most of the Cenozoic and that sensitivity must have increased by at least a factor of 2 during the Plio‐Pleistocene. Our results imply that slow feedbacks will raise global surface temperatures by more than 3°C in the coming millennia, even if anthropogenic forcing is stabilized at the present‐day value (2 W/m2), and that their impact will diminish with further warming.
Heterogeneous Fossil Réunion Plume Component in the Source Region of Enriched MORB Along the Central Indian Ridge Between 12° and 17°S
Authors: Vincent Clément , Park Jung‐Woo , Lee Sang‐Mook , Kim Jonguk , Lee Mi‐Jung , Révillon Sidonie
Published: December 2022

Mid‐ocean ridge basalts (MORB) from the Central Indian Ridge (CIR) between 12° and 17°S show a wide range of geochemical and isotopic variations. Particularly, MORB from a segment between 14° and 15°S are more enriched in incompatible trace elements with more radiogenic Sr and Pb isotope and unradiogenic Nd isotope values than the lavas between 15° and 16°S with geochemical features of normal MORB. However, the causes for the enrichment between 14° and 15°S are poorly constrained. In this study, we re‐examined the CIR MORB from 12° to 17°S with new geochemical data obtained based on high spatial resolution sampling to better understand the nature of the enriched mantle source. Our new geochemical data show that the MORB between 14° and 15°S, with maximum values for (La/Sm)N = 1.95, 87Sr/86Sr = 0.703526 and 206Pb/204Pb = 18.7558, are more enriched than those from the southern segments (16° to 20°S) known to be influenced by the Réunion mantle component. The new trace element and isotopic compositions of MORB suggest that three mantle end‐members are required to explain the geochemical variations shown between 14° and 16°S: the depleted Indian‐type MORB mantle, Réunion Plume (RP), and Seychelles/Madagascar‐like continental crust components. Moreover, our mixing model suggests that the differences in enriched MORB signature from 14° to 20°S are due to variable proportions of continental material previously mixed with the RP. Our study implies that a continental component interacted with the plume into the asthenosphere, possibly beneath Madagascar or below Mauritius Island and the Mascarene plateau.
Drivers of Decadal Carbon Fluxes Across Temperate Ecosystems
Authors: Desai Ankur R. , Murphy Bailey A. , Wiesner Susanne , Thom Jonathan , Butterworth Brian J. , Koupaei‐Abyazani Nikaan , Muttaqin Andi , Paleri Sreenath , Talib Ammara , Turner Jess , Mineau James , Merrelli Aronne , Stoy Paul , Davis Ken
Published: December 2022

Long‐running eddy covariance flux towers provide insights into how the terrestrial carbon cycle operates over multiple timescales. Here, we evaluated variation in net ecosystem exchange (NEE) of carbon dioxide (CO2) across the Chequamegon Ecosystem‐Atmosphere Study AmeriFlux core site cluster in the upper Great Lakes region of the USA from 1997 to 2020. The tower network included two mature hardwood forests with differing management regimes (US‐WCr and US‐Syv), two fen wetlands with varying levels of canopy sheltering and vegetation (US‐Los and US‐ALQ), and a very tall (400 m) landscape‐level tower (US‐PFa). Together, they provided over 70 site‐years of observations. The 19‐tower Chequamegon Heterogenous Ecosystem Energy‐balance Study Enabled by a High‐density Extensive Array of Detectors 2019 campaign centered around US‐PFa provided additional information on the spatial variation of NEE. Decadal variability was present in all long‐term sites, but cross‐site coherence in interannual NEE in the earlier part of the record became weaker with time as non‐climatic factors such as local disturbances likely dominated flux time series. Average decadal NEE at the tall tower transitioned from carbon source to sink to near neutral over 24 years. Respiration had a greater effect than photosynthesis on driving variations in NEE at all sites. Declining snowfall offset potential increases in assimilation from warmer springs, as less‐insulated soils delayed start of spring green‐up. Higher CO2 increased maximum net assimilation parameters but not total gross primary productivity. Stand‐scale sites were larger net sinks than the landscape tower. Clustered, long‐term carbon flux observations provide value for understanding the diverse links between carbon and climate and the challenges of upscaling these responses across space.
Differences in Traumatic Stress Among Youth With and Without Chronic Medical Conditions During the COVID-19 Pandemic
Authors: Paternostro Jennifer K. , Kakolu Anusha , Boyd Willard , Conrad Amy L. , Wilgenbusch Tammy
Published: December 2022

Objective:

The COVID-19 pandemic is the deadliest pandemic in American history. This study aims to assess the differences in youth reported traumatic stress among those with and without chronic illness, and how those reports are impacted by parental level of concern regarding the COVID-19 pandemic.

Methods:

Using convenience sampling, parents and their children completed a series of questionnaires focused on demographic information including questions about medical conditions, parental level of concern about COVID-19, and youth-report of posttraumatic stress symptoms.

Results:

Results of the anonymous survey ( n = 164) found that parental reported level of concern of COVID-19 significantly predicted youth report of posttraumatic stress symptoms ( F(4, 159) = 2.607, p = .038). There was no significant difference in youth-report of posttraumatic stress symptoms between youth with and without chronic medical conditions ( F(1, 162) = .438, p = .509).

Conclusions:

Children often look to their parents for guidance during stressful life events, as confirmed by our findings. Parental emotional and behavioral responses may influence how youth make sense of highly stressful events and should be considered when determining intervention strategies in the COVID-19 era.

Implications for Impact Statement

This study found that youth with and without chronic health conditions did not differ in their report of posttraumatic stress 6 months after the onset of the COVID-19 pandemic. However, youth report of traumatic stress symptoms was predicted by their parents’ level of concern regarding the impact of COVID-19 on their families, suggesting the need for targeted parent-based intervention. Clinical interventions to prevent chronic posttraumatic stress responses in youth regardless of medical comorbidity are discussed.
A novel SLC5A2 heterozygous variant in a family with familial renal glucosuria
Authors: Hatano Maho , Udagawa Tomohiro , Kanamori Toru , Sutani Akito , Mori Takayasu , Sohara Eisei , Uchida Shinichi , Morio Tomohiro , Nishioka Masato
Published: December 2022

Familial renal glucosuria (FRG) is characterized by persistent glucosuria despite normal blood glucose levels in the absence of overt tubular dysfunction. SGLT2 is a sodium-glucose cotransporter expressed in the proximal tubule; loss-of-function variants in SLC5A2 are the primary cause of FRG. Heterozygous variants have rarely been reported in Japanese individuals. Here, we identified a novel SLC5A2 heterozygous variant, c.1348G>T: p.Gly450Trp, in a Japanese family comprising two children and their father.
Host-dependent resistance of Group A Streptococcus to sulfamethoxazole mediated by a horizontally-acquired reduced folate transporter
Authors: Rodrigo M. Kalindu D. , Saiganesh Aarti , Hayes Andrew J. , Wilson Alisha M. , Anstey Jack , Pickering Janessa L. , Iwasaki Jua , Hillas Jessica , Winslow Scott , Woodman Tabitha , Nitschke Philipp , Lacey Jake A. , Breese Karen J. , van der Linden Mark P. G. , Giffard Philip M. , Tong Steven Y. C. , Gray Nicola , Stubbs Keith A. , Carapetis Jonathan R. , Bowen Asha C. , Davies Mark R. , Barnett Timothy C.
Published: December 2022

Described antimicrobial resistance mechanisms enable bacteria to avoid the direct effects of antibiotics and can be monitored by in vitro susceptibility testing and genetic methods. Here we describe a mechanism of sulfamethoxazole resistance that requires a host metabolite for activity. Using a combination of in vitro evolution and metabolic rescue experiments, we identify an energy-coupling factor (ECF) transporter S component gene (thfT) that enables Group A Streptococcus to acquire extracellular reduced folate compounds. ThfT likely expands the substrate specificity of an endogenous ECF transporter to acquire reduced folate compounds directly from the host, thereby bypassing the inhibition of folate biosynthesis by sulfamethoxazole. As such, ThfT is a functional equivalent of eukaryotic folate uptake pathways that confers very high levels of resistance to sulfamethoxazole, yet remains undetectable when Group A Streptococcus is grown in the absence of reduced folates. Our study highlights the need to understand how antibiotic susceptibility of pathogens might function during infections to identify additional mechanisms of resistance and reduce ineffective antibiotic use and treatment failures, which in turn further contribute to the spread of antimicrobial resistance genes amongst bacterial pathogens.
Splay-bend nematic phases of bent colloidal silica rods induced by polydispersity
Authors: Kotni Ramakrishna , Grau-Carbonell Albert , Chiappini Massimiliano , Dijkstra Marjolein , van Blaaderen Alfons
Published: December 2022

Liquid crystal (LC) phases are in between solids and liquids with properties of both. Nematic LCs composed of rod-like molecules or particles exhibit long-range orientational order, yielding characteristic birefringence, but they lack positional order, allowing them to flow like a liquid. This combination of properties as well as their sensitivity to external fields make nematic LCs fundamental for optical applications e.g. liquid crystal displays (LCDs). When rod-like particles become bent, spontaneous bend deformations arise in the LC, leading to geometric frustration which can be resolved by complementary twist or splay deformations forming intriguing twist-bend (NTB) and splay-bend (NSB) nematic phases. Here, we show experimentally that the elusive NSB phases can be stabilized in systems of polydisperse micron-sized bent silica rods. Our results open avenues for the realization of NTB and NSB phases of colloidal and molecular LCs.
An increase in marine heatwaves without significant changes in surface ocean temperature variability
Authors: Xu Tongtong , Newman Matthew , Capotondi Antonietta , Stevenson Samantha , Di Lorenzo Emanuele , Alexander Michael A.
Published: December 2022

Marine heatwaves (MHWs)—extremely warm, persistent sea surface temperature (SST) anomalies causing substantial ecological and economic consequences—have increased worldwide in recent decades. Concurrent increases in global temperatures suggest that climate change impacted MHW occurrences, beyond random changes arising from natural internal variability. Moreover, the long-term SST warming trend was not constant but instead had more rapid warming in recent decades. Here we show that this nonlinear trend can—on its own—appear to increase SST variance and hence MHW frequency. Using a Linear Inverse Model to separate climate change contributions to SST means and internal variability, both in observations and CMIP6 historical simulations, we find that most MHW increases resulted from regional mean climate trends that alone increased the probability of SSTs exceeding a MHW threshold. Our results suggest the need to carefully attribute global warming-induced changes in climate extremes, which may not always reflect underlying changes in variability.
Qubit vitrification and entanglement criticality on a quantum simulator
Authors: Côté Jeremy , Kourtis Stefanos
Published: December 2022

Many elusive quantum phenomena emerge from a quantum system interacting with its classical environment. Quantum simulators enable us to program this interaction by using measurement operations. Measurements generally remove part of the entanglement built between the qubits in a simulator. While in simple cases entanglement may disappear at a constant rate as we measure qubits one by one, the evolution of entanglement under measurements for a given class of quantum states is generally unknown. We show that consecutive measurements of qubits in a simulator can lead to criticality, separating two phases of entanglement. Using up to 48 qubits, we prepare an entangled superposition of ground states to a classical spin model. Progressively measuring the qubits drives the simulator through an observable vitrification point and into a spin glass phase of entanglement. Our findings suggest coupling to a classical environment may drive critical phenomena in more general quantum states.
Dietary glucosamine overcomes the defects in αβ-T cell ontogeny caused by the loss of de novo hexosamine biosynthesis
Authors: Werlen Guy , Li Mei-Ling , Tottone Luca , da Silva-Diz Victoria , Su Xiaoyang , Herranz Daniel , Jacinto Estela
Published: December 2022

T cell development requires the coordinated rearrangement of T cell receptor (TCR) gene segments and the expression of either αβ or γδ TCR. However, whether and how de novo synthesis of nutrients contributes to thymocyte commitment to either lineage remains unclear. Here, we find that T cell-specific deficiency in glutamine:fructose-6-phosphate aminotransferase 1 (GFAT1), the rate-limiting enzyme of the de novo hexosamine biosynthesis pathway (dn-HBP), attenuates hexosamine levels, blunts N-glycosylation of TCRβ chains, reduces surface expression of key developmental receptors, thus impairing αβ-T cell ontogeny. GFAT1 deficiency triggers defects in N-glycans, increases the unfolded protein response, and elevates  γδ-T cell numbers despite reducing γδ-TCR diversity. Enhancing TCR expression or PI3K/Akt signaling does not reverse developmental defects. Instead, dietary supplementation with the salvage metabolite, glucosamine, and an α-ketoglutarate analogue partially restores αβ-T cell development in GFAT1T-/- mice, while fully rescuing it in ex vivo fetal thymic organ cultures. Thus, dn-HBP fulfils, while salvage nutrients partially satisfy, the elevated demand for hexosamines during early T cell development.
The BrightEyes-TTM as an open-source time-tagging module for democratising single-photon microscopy
Authors: Rossetta Alessandro , Slenders Eli , Donato Mattia , Zappone Sabrina , Fersini Francesco , Bruno Martina , Diotalevi Francesco , Lanzanò Luca , Koho Sami , Tortarolo Giorgio , Barberis Andrea , Crepaldi Marco , Perego Eleonora , Vicidomini Giuseppe
Published: December 2022

Fluorescence laser-scanning microscopy (LSM) is experiencing a revolution thanks to new single-photon (SP) array detectors, which give access to an entirely new set of single-photon information. Together with the blooming of new SP LSM techniques and the development of tailored SP array detectors, there is a growing need for (i) DAQ systems capable of handling the high-throughput and high-resolution photon information generated by these detectors, and (ii) incorporating these DAQ protocols in existing fluorescence LSMs. We developed an open-source, low-cost, multi-channel time-tagging module (TTM) based on a field-programmable gate array that can tag in parallel multiple single-photon events, with 30 ps precision, and multiple synchronisation events, with 4 ns precision. We use the TTM to demonstrate live-cell super-resolved fluorescence lifetime image scanning microscopy and fluorescence lifetime fluctuation spectroscopy. We expect that our BrightEyes-TTM will support the microscopy community in spreading SP-LSM in many life science laboratories.
Signatures of a magnetic-field-induced Lifshitz transition in the ultra-quantum limit of the topological semimetal ZrTe5
Authors: Galeski S. , Legg H. F. , Wawrzyńczak R. , Förster T. , Zherlitsyn S. , Gorbunov D. , Uhlarz M. , Lozano P. M. , Li Q. , Gu G. D. , Felser C. , Wosnitza J. , Meng T. , Gooth J.
Published: December 2022

The quantum limit (QL) of an electron liquid, realised at strong magnetic fields, has long been proposed to host a wealth of strongly correlated states of matter. Electronic states in the QL are, for example, quasi-one dimensional (1D), which implies perfectly nested Fermi surfaces prone to instabilities. Whereas the QL typically requires unreachably strong magnetic fields, the topological semimetal ZrTe5 has been shown to reach the QL at fields of only a few Tesla. Here, we characterize the QL of ZrTe5 at fields up to 64 T by a combination of electrical-transport and ultrasound measurements. We find that the Zeeman effect in ZrTe5 enables an efficient tuning of the 1D Landau band structure with magnetic field. This results in a Lifshitz transition to a 1D Weyl regime in which perfect charge neutrality can be achieved. Since no instability-driven phase transitions destabilise the 1D electron liquid for the investigated field strengths and temperatures, our analysis establishes ZrTe5 as a thoroughly understood platform for potentially inducing more exotic interaction-driven phases at lower temperatures.