bluuebunny/crossref_metadata_2025 huggingface dataset:
Remagnetization Under Hydrothermal Alteration of South Tibetan Paleocene Lavas: Maghemitization, Hematization, and Grain Size Reduction of (Titano)magnetite
Authors: Huang Wentao , Niu Shanshan , Dekkers Mark J. , Lippert Peter C. , Bilardello Dario , Solheid Peat , Zhang Bo , Dupont‐Nivet Guillaume , van Hinsbergen Douwe J. J. , Ding Lin
Published: March 2023

The Paleocene lavas from Dianzhong Formation (E1d) in Linzhou basin of southern Lhasa terrane are a key target for paleomagnetic investigations into the timing and paleolatitude of the initial India‐Asia collision. Controversy exists, however, on whether these rocks preserve a primary remanent magnetization. Here we reanalyze previously published thermal demagnetization data and report detailed rock magnetic results and petrographic observations of these rocks. We find that the original magnetic carrier, a magmatic multidomain Ti‐poor titanomagnetite, underwent significant grain size reduction and was variably reacted to single‐domain maghemite and nano‐hematite. Such strong alteration may have resulted from successive hydrothermal events: a first event related to the ∼52 Ma dike intrusions into the E1d that accompanied a massive ignimbrite eruption deposited above the E1d producing heating up to 300°C; and a secondary event related to the 42–27 Ma southward overthrusting of the basin, heating the E1d up to 130–145°C. Unblocking/inversion temperature spectra of the authigenic maghemite and nano‐hematite overlap with those of the titanomagnetite, implying that the primary remanence of the E1d lavas has been contaminated or replaced by thermoviscous and chemical remanent magnetizations. Thus the isolated characteristic remanent magnetization from these rocks, whether slightly or completely altered, cannot be considered primary and should not be used for paleolatitudinal determination. Our study confirms that hydrothermal alteration can seriously jeopardize the remanence carried by titanomagnetite and thus should be tested for paleomagnetic investigations of rock units from tectonically active areas.
Imaging flow cytometry-based multiplex FISH for three IGH translocations in multiple myeloma
Authors: Tsukamoto Taku , Kinoshita Masaki , Yamada Kazuhiro , Ito Hodaka , Yamaguchi Toshikazu , Chinen Yoshiaki , Mizutani Shinsuke , Fujino Takahiro , Kobayashi Tsutomu , Shimura Yuji , Inazawa Johji , Kuroda Junya
Published: March 2023

Three types of chromosomal translocations, t(4;14)(p16;q32), t(14;16)(q32;q23), and t(11;14)(q13;q32), are associated with prognosis and the decision making of therapeutic strategy for multiple myeloma (MM). In this study, we developed a new diagnostic modality of the multiplex FISH in immunophenotyped cells in suspension (Immunophenotyped-Suspension-Multiplex (ISM)-FISH). For the ISM-FISH, we first subject cells in suspension to the immunostaining by anti-CD138 antibody and, then, to the hybridization with four different FISH probes for genes ofIGH,FGFR3,MAF, andCCND1tagged by different fluorescence in suspension. Then, cells are analyzed by the imaging flow cytometry MI-1000 combined with the FISH spot counting tool. By this system of the ISM-FISH, we can simultaneously examine the three chromosomal translocations, i.e, t(4;14), t(14;16), and t(11;14), in CD138-positive tumor cells in more than 2.5 × 104nucleated cells with the sensitivity at least up to 1%, possibly up to 0.1%. The experiments on bone marrow nucleated cells (BMNCs) from 70 patients with MM or monoclonal gammopathy of undetermined significance demonstrated the promising qualitative diagnostic ability in detecting t(11;14), t(4;14), and t(14;16) of our ISM-FISH, which was more sensitive compared with standard double-color (DC) FISH examining 200 interphase cells with its best sensitivity up to 1.0%. Moreover, the ISM-FISH showed a positive concordance of 96.6% and negative concordance of 98.8% with standard DC-FISH examining 1000 interphase cells. In conclusion, the ISM-FISH is a rapid and reliable diagnostic tool for the simultaneous examination of three critically importantIGHtranslocations, which may promote risk-adapted individualized therapy in MM.
Two-step structural changes in M3 muscarinic receptor activation rely on the coupled Gq protein cycle
Authors: Kim Yong-Seok , Yeon Jun-Hee , Ko Woori , Suh Byung-Chang
Published: March 2023

G protein-coupled receptors (GPCRs) regulate diverse intracellular signaling pathways through the activation of heterotrimeric G proteins. However, the effects of the sequential activation–deactivation cycle of G protein on the conformational changes of GPCRs remains unknown. By developing a Förster resonance energy transfer (FRET) tool for human M3 muscarinic receptor (hM3R), we find that a single-receptor FRET probe can display the consecutive structural conversion of a receptor by G protein cycle. Our results reveal that the G protein activation evokes a two-step change in the hM3R structure, including the fast step mediated by Gq protein binding and the subsequent slower step mediated by the physical separation of the Gαq and Gβγ subunits. We also find that the separated Gαq-GTP forms a stable complex with the ligand-activated hM3R and phospholipase Cβ. In sum, the present study uncovers the real-time conformational dynamics of innate hM3R during the downstream Gq protein cycle.
A Shigella flexneri 2a synthetic glycan-based vaccine induces a long-lasting immune response in adults
Authors: Meron-Sudai Shiri , Asato Valeria , Adler Amos , Bialik Anya , Goren Sophy , Ariel-Cohen Ortal , Reizis Arava , Mulard Laurence A. , Phalipon Armelle , Cohen Dani
Published: March 2023

Shigella is a leading cause of moderate to severe diarrhea worldwide and of diarrhea-associated deaths in children under 5 years of age in low-and middle-income countries. A vaccine against shigellosis is in high demand. SF2a-TT15, a synthetic carbohydrate-based conjugate vaccine candidate against Shigella flexneri 2a (SF2a) was found safe and strongly immunogenic in adult volunteers. Here, SF2a-TT15 at 10 µg oligosaccharide (OS) vaccine dose is shown to induce a sustained immune response in magnitude and functionality in the majority of volunteers followed up 2 and 3 years post-vaccination. High levels of either one of the humoral parameters as well as the number of specific-IgG memory B-cells determined 3 months after vaccination were good predictors of the durability of the immune response. This study is the first to examine the long-term durability of antibody functionality and memory B-cell response induced by a Shigella vaccine candidate.
Annotated computed tomography coronary angiogram images and associated data of normal and diseased arteries
Authors: Gharleghi R. , Adikari D. , Ellenberger K. , Webster M. , Ellis C. , Sowmya A. , Ooi S. , Beier S.
Published: March 2023

Computed Tomography Coronary Angiography (CTCA) is a non-invasive method to evaluate coronary artery anatomy and disease. CTCA is ideal for geometry reconstruction to create virtual models of coronary arteries. To our knowledge there is no public dataset that includes centrelines and segmentation of the full coronary tree. We provide anonymized CTCA images, voxel-wise annotations and associated data in the form of centrelines, calcification scores and meshes of the coronary lumen in 20 normal and 20 diseased cases. Images were obtained along with patient information with informed, written consent as part of the Coronary Atlas. Cases were classified as normal (zero calcium score with no signs of stenosis) or diseased (confirmed coronary artery disease). Manual voxel-wise segmentations by three experts were combined using majority voting to generate the final annotations. Provided data can be used for a variety of research purposes, such as 3D printing patient-specific models, development and validation of segmentation algorithms, education and training of medical personnel and in-silico analyses such as testing of medical devices.
Assessment of aerosol persistence in ICUs via low-cost sensor network and zonal models
Authors: Glenn K. , He J. , Rochlin R. , Teng S. , Hecker J. G. , Novosselov I.
Published: March 2023

The COVID-19 pandemic raised public awareness about airborne particulate matter (PM) due to the spread of infectious diseases via the respiratory route. The persistence of potentially infectious aerosols in public spaces and the spread of nosocomial infections in medical settings deserve careful investigation; however, a systematic approach characterizing the fate of aerosols in clinical environments has not been reported. This paper presents a methodology for mapping aerosol propagation using a low-cost PM sensor network in ICU and adjacent environments and the subsequent development of the data-driven zonal model. Mimicking aerosol generation by a patient, we generated trace NaCl aerosols and monitored their propagation in the environment. In positive (closed door) and neutral-pressure (open door) ICUs, up to 6% or 19%, respectively, of all PM escaped through the door gaps; however, the outside sensors did not register an aerosol spike in negative-pressure ICUs. The K-means clustering analysis of temporospatial aerosol concentration data suggests that ICU can be represented by three distinct zones: (1) near the aerosol source, (2) room periphery, and (3) outside the room. The data suggests two-phase plume behavior: dispersion of the original aerosol spike throughout the room, followed by an evacuation phase where "well-mixed" aerosol concentration decayed uniformly. Decay rates were calculated for positive, neutral, and negative pressure operations, with negative-pressure rooms clearing out nearly twice as fast. These decay trends closely followed the air exchange rates. This research demonstrates the methodology for aerosol monitoring in medical settings. This study is limited by a relatively small data set and is specific to single-occupancy ICU rooms. Future work needs to evaluate medical settings with high risks of infectious disease transmission.
Preparation of aluminium-hydroxide-modified diatomite and its fluoride adsorption mechanism
Authors: Xiang Biao , Tang Jiaxi , Feng Xiaojie , Zhu Yongle , Li Yu , Tan Ting
Published: March 2023

As the current excessive accumulation of fluoride (F−) in the environment can be hazardous to human health, it is essential to remove fluoride from wastewater. In this study, diatomite (DA) was used as a raw material and modified using aluminum hydroxide (Al-DA) for use in the adsorption of F− from water bodies. SEM, EDS, XRD, FTIR, and Zeta potential characterization analyses were carried out; adsorption tests and kinetic fitting were performed, and the effects of pH, dosing quantity, and presence of interfering ions on the adsorption of F− by the materials were investigated. The results show that the Freundlich model effectively describes the adsorption process of F− on DA, which therefore involves adsorption-complexation interactions; however, the Langmuir model effectively describes the adsorption process of F− on Al-DA, corresponding to unimolecular layer adsorption mainly via ion-exchange interactions, that is, adsorption is dominated by chemisorption. Aluminum hydroxide was shown to be the main species involved in F− adsorption. The efficiency of F− removal by DA and Al-DA was over 91% and 97% for 2 h, and the adsorption kinetics were effectively fit by the quasi-secondary model, suggesting that chemical interactions between the absorbents and F− control the adsorption process. The adsorption of F− was highly dependent on the pH of the system, and the maximum adsorption performance was obtained at pH 6 and 4. The optimal dosage of DA and Al-DA was 4 g/L. Even in the presence of interfering ions, the removal of F− on Al-DA reached 89%, showing good selectivity. XRD and FTIR studies showed that the mechanism of F− adsorption on Al-DA involved ion exchange and the formation of F–Al bonds.
Neurological outcomes after surgery and postoperative rehabilitation for cervical radiculopathy due to disc disease: a 2-year-follow-up of a randomized clinical trial
Authors: Peolsson Anneli , Löfgren Håkan , Dedering Åsa , Kristedal Mattias , Öberg Birgitta , Zsigmond Peter , Wibault Johanna
Published: March 2023

Reports on neurological outcomes in patients with cervical radiculopathy (CR) undergoing surgery and postoperative rehabilitation are important to inform prognosis. This 2-year-follow-up of a randomized clinical trial aimed to compare secondary neurological outcomes between structured postoperative rehabilitation and a standard approach after surgery for CR. A secondary aim was to increase knowledge about recovery of neurological impairments in relation to patient-reported neck disability. Neurological outcomes included assessment of sensibility, motor function, arm reflexes and the Spurling test. A total of 153 and 135 participants (> 70% response rate) completed the clinical examination. Between-group differences, changes over time, and associations between persistent neurological impairments and the Neck Disability Index were investigated. No between-group differences were reported (p > 0.07), and neurological impairments in sensibility, motor function, and a positive Spurling test decreased over time in both groups (p < 0.04). Persistent impairments in sensibility and reflex arm were most frequent at follow-up, whereas, a persistent positive Spurling test, and impairments in motor function were associated with higher NDI score. Neurological outcomes improved over time in patients undergoing surgery for CR with no between-group differences., However, persistent neurological impairments were common, and associated with poorer outcome for patient-reported neck disability.

Clinical registration: clinicaltrial.gov NCT01547611, 08/03/2012, Title: Outcome of physiotherapy after surgery for cervical disc disease: a prospective multi-centre trial.
Highly efficient utilization of sodium storage sites for MOF-derived carbon by rapid carbonization
Authors: Zhao Hanqing , Chang Gaobo , Wang Yaoyao , Zhao Dan , Li Zhong
Published: March 2023

Sodium storage sites and electronic conductivity were achieved simultaneously in MOF-derived carbon by rapid carbonization.
Flower-like TiO2 and TiO2@C composites prepared via a one-pot solvothermal method as anode materials for lithium-ion batteries: higher capacity and excellent cycling stability
Authors: Shi Huili , Shi Chaoyun , Jia Zhitong , Li Ao , He Binfang , Li Tianxiang , Chen Jingbo
Published: March 2023

TiO2 is a promising and safe anode material for lithium-ion batteries.
The impact of plug-in fragrance diffusers on residential indoor VOC concentrations
Authors: Warburton Thomas , Grange Stuart K. , Hopkins James R. , Andrews Stephen J. , Lewis Alastair C. , Owen Neil , Jordan Caroline , Adamson Greg , Xia Bin
Published: March 2023

The effect of adding a plug-in air freshener into 60 houses was hard to detect due to pre-existing VOCs from other sources; in homes with low ventilation rates however small increases in monoterpenes were seen, consistent with emission rates.
Large-area 2D bismuth antimonide with enhanced thermoelectric properties via multiscale electron–phonon decoupling
Authors: Zhao Hanliu , Xue Yuxin , Zhao Yu , Chen Jiayi , Chang Bo , Huang Hao , Xu Tao , Sun Litao , Chen Yunfei , Sha Jingjie , Zhu Beibei , Tao Li
Published: March 2023

Multiscale defect engineering has been designed to decouple the electron–phonon transport in 2D bismuth antimony, simultaneously achieving high electrical and low thermal conductivity with 420% enhancement of the ZT value.
The effect of π-linker bulk on the photophysical properties of 2-phenylfuro[2,3-b]quinoxaline-based FQ–π–FQ-type compounds
Authors: Wu ChuanMing , Wu MingXin , Zhang BoHua , MeiTing Luo , Wang DongDong , Wu Yong , Yang GuoXin , Gou Lei , Wu Zhaoxin
Published: March 2023

Employing a 2-phenylfuro[2,3-b]quinoxaline scaffold as a fluorophore, and phenyl, biphenyl, anthracene and benzothiadiazole as π-linkers, Ph-dFQ, bPh-dFQ, ADN-dFQ and Bth-dFQ were constructed, along with BIZ-FQ with a benzimidazole unit, to screen suitable blue emitters.
Stabilisation and reactivity studies of donor-base ligand-supported gallium-phosphides with stronger binding energy: a theoretical approach
Authors: Francis Maria , Roy Sudipta
Published: March 2023

Gallium phosphide is a three-dimensional polymeric material of hetero-diatomic GaP unit. Our studies reveal the synthetic viability of donor base-stabilised monomeric Ga–P compounds with stronger binding energy, and explore their reactivity with metal carbonyls.
Polyimide/crown ether composite film with low dielectric constant and low dielectric loss for high signal transmission
Authors: Li Heming , Wang Xinming , Gong Yuze , Zhao Hongbin , Liu Zhaobin , Tao Lin , Peng Youyou , Ma Ke , Hu Zhizhi , Dastan Davoud
Published: March 2023

Three kinds of fluorinated PI/CEs composite films prepared by a thermal imidization process have a low dielectric constant and low dielectric loss at a high frequency (10 GHz).
Synthesis of graphene derivatives from asphaltenes and effect of carbonization temperature on their structural parameters
Authors: AlHumaidan Faisal S. , Rana Mohan S. , Vinoba Mari , AlSheeha Hanadi M. , Ali Afnan A. , Navvamani R.
Published: March 2023

The TEM results revealed that asphaltene tangled structure has nearly disappeared after severe thermal treatment due to alkyl side chain removal, which is also confirmed by the Raman and FTIR analyses.
“I am here because I wanted to shine”: how poetry can be used to better understand undergraduate students’ first-year chemistry or related course experiences
Authors: Illingworth Sam , Radhakrishnan Mala L.
Published: March 2023

In this study we investigate how first-year chemistry/biology undergraduate students’ original poetry can be used as a reflective tool for others to understand their course experiences. By inviting students from an integrated first-year chemistry/biology course to write poetry about their experiences, we use poetic content analysis as a qualitative research method to analyze the students’ responses to an open-ended prompt. In analyzing the poetry, four major categories emerged: knowledge, community, emotions, and identity, each of which includes examples that reflect and enhance our understanding of well-documented milestones and ideas in the literature regarding first-year student academic experiences, therefore highlighting the extent to which poetry can be useful in this regard. In presenting these findings we also demonstrate how such an approach might be used by others to better understand student experiences, including those related to learning, belonging, and/or identity in their introductory chemistry or related courses.
Correlating microscopic viscoelasticity and structure of an aging colloidal gel using active microrheology and cryogenic scanning electron microscopy
Authors: Biswas Rajkumar , Parmar Vaibhav Raj Singh , Thambi Anson G , Bandyopadhyay Ranjini
Published: March 2023

Mechanical moduli, extracted from optical tweezer-based microrheology, are correlated with suspension microstructure data obtained using cryogenic scanning electron microscopy.
Surface electron modulation of a plasmonic semiconductor for enhanced CO2 photoreduction
Authors: Tian Dehua , Lu Changhai , Shi Xiaowei , Wu Haifeng , Liu Lu , Mai Wenjie , Li Baojun , Li Juan , Lou Zaizhu
Published: March 2023

Plasmonic Bi2WO6 nanodots with oxygen vacancy-induced electron trapping states were controllably grown on TiO2 nanosheets as plasmonic heterostructures to break the limitation of surface depletion layer for efficient photocatalysis.
Interfacial charge transfer weakens hydrogen bonds between water molecules to accelerate solar water evaporation
Authors: Wang Liru , Lin Jinguo , Li Yuanyuan , Yang Yanan , Liu Xiaoting , Wang Zhe , Liu Feng , Sun Xiaotong , Yang Tian , Chen Nan , Qu Liangti
Published: March 2023

A highly polar surface photothermal material is designed to weaken the strength of the hydrogen bond between the intermediate water (IW) and the bound water (BW) to improve the water evaporation rate of the interface solar absorber.
Iron nitroprusside as a chemodynamic agent and inducer of ferroptosis for ovarian cancer therapy
Authors: Asif Kanwal , Adeel Muhammad , Rahman Md. Mahbubur , Caligiuri Isabella , Perin Tiziana , Cemazar Maja , Canzonieri Vincenzo , Rizzolio Flavio
Published: March 2023

A schematic representation of FeNP-induced ROS production and its involvement in ferroptosis.
An electrospun cellulose-based nanofiber piezoelectric membrane with enhanced flexibility and pressure sensitivity
Authors: Zhang Minghao , Hu Ke , Meng Qingyu , Lan Zhuyue , Shi Shitao , Sun Qingfeng , Zhou Lei , Shen Xiaoping
Published: March 2023

An electrospun cellulose diacetate (CDA)–silica–lead zirconate titanate (PZT) hybrid nanofiber-based piezoelectric mat with superior homogeneity, flexibility, piezoelectricity and pressure sensitivity was prepared.
Two-dimensional borocarbonitrides for photocatalysis and photovoltaics
Authors: Zhang Wei , Chai Changchun , Fan Qingyang , Yang Yintang , Sun Minglei , Palummo Maurizia , Schwingenschlögl Udo
Published: March 2023

We have designed 2D borocarbonitrides with outstanding material properties and potential applications in a variety of important technological fields, including nano-mechanics, electronics, photocatalysis, and photovoltaics.
Controllable synthesis of MoS2@TiO2nanocomposites for visual detection of dopamine secretion with highly-efficient enzymatic activity
Authors: Wei Chonghui , Xie Xuan , Mou Yue , Cheng Shiqi , Yang Jin , Xue Kaixin , Yu Kewei , Lin Xinru , Zhang Chunfen , Zhao Yujie , Luo Xingyu , Wang Yilin
Published: March 2023

Facile method and specific reactant mass ratio for nanocomposite synthesis and dopamine detection.
Tailoring the positive and negative solvatochromism for chalcone analogues to detect heterozygous protein co-aggregation
Authors: Yulong Bai , Wang Wan , Yanan Huang , Jichun Wu , Lihua Liu , Biao Jing , Junlin Chen , Xin Zhang , Yu Liu
Published: March 2023

Modulating solvatochromism and anti-solvatochromism in a single fluorophore scaffold was achieved and these probes were utilized in visualizing biochemical processes.
Study on the crystallization behavior and conformation adjustment scale of poly(lactic acid) in the terahertz frequency range
Authors: Zhu Zhenqi , Bian Yujing , Zhang Xun , Zeng Ruonan , Yang Bin
Published: March 2023

The observed properties of crystalline polymers are determined by their internal structure, which in turn is the result of their different crystallization behaviors.
Comparative studies of hexagonal boron phosphide/V2CS2 heterostructure and homogeneous bilayers as metal-ion battery anodes
Authors: Yuan Xian , Zhang Zhongyong , He Yuping , Zhou Naigen
Published: March 2023

h-BP/V2CS2 heterostructures have better storage performance than its building blocks in metal-ion batteries.
Site-selective occupation, optical spectrum regulation and photoluminescence property investigation of Eu2+-activated blue light-excited yellow-orange emitting phosphors
Authors: Sun Wenzhi , Zhao Tingting , Wang Shuya , Wei Denghu , Jiao Mengmeng , Zhang Hongwu
Published: March 2023

By doping with Ca2+ or Ba2+, Eu2+ emitting centers will selectively occupy different Sr2+ sites, thus leading to the regulation of optical spectra of SCxMPO:Eu2+ and SByMPO:Eu2+, with emission colors gradually turning from yellow to orange (λex = 460 nm).
Hierarchical V4C3TX@NiO-reduced graphene oxide heterostructure hydrogels and defective reduced graphene oxide hydrogels as free-standing anodes and cathodes for high-performance asymmetric supercapacitors
Authors: Geng Ziyu , Chen Weiwen , Qiu Zenghui , Xu Haijun , Pan Dingjie , Chen Shaowei
Published: March 2023

A high-performance V4C3TX@NiO-RGO//DRGO asymmetric supercapacitor device is assembled based on a 3D free-standing V4C3TX@NiO-RGO hydrogel as a positive electrode and a 3D DRGO hydrogel as a negative electrode.
Spatial separation of redox centers for boosting cooperative photocatalytic hydrogen evolution with oxidation coupling of benzylamine over Pt@UiO-66-NH2@ZnIn2S4
Authors: Wang Lianlian , Zhao Yujie , Zhang Bin , Wu Gaigai , Wu Jie , Hou Hongwei
Published: March 2023

Pt@UiO-66-NH2@ZIS is prepared to realize the co-production of H2and C–N coupling products. DFT calculations of interfacial charges reveal that spatial separation of redox centers has a significant catalytic effect on dual-functional systems.
Supported transition metal (Mo, W) carbide and nitride catalysts for lignin hydrodeoxygenation: interplay of supports, structure, and catalysis
Authors: Ji Na , Ri Poknam , Diao Xinyong , Rong Yue , Kim Changsok
Published: March 2023

In-depth understanding of the structure–performance relationship for transition metal (Mo, W) carbide- and nitride-catalyzed lignin hydrodeoxygenation was summarized.
9-Borafluoren-9-yl and diphenylboron tetracoordinate complexes of F- and Cl-substituted 8-quinolinolato ligands: synthesis, molecular and electronic structures, fluorescence and application in OLED devices
Authors: Fialho Carina B. , Cruz Tiago F. C. , Rodrigues Ana I. , Calhorda Maria José , Vieira Ferreira Luís F. , Pander Piotr , Dias Fernando B. , Morgado Jorge , Maçanita António L. , Gomes Pedro T.
Published: March 2023

Tetrahedral 9-borafluoren-9-yl and diphenylboron complexes, with fluorine- and chlorine-substituted 8-quinolinolato ligand chromophores, were synthesised, characterised and applied as emitters in OLEDs.
Pulsed electrolysis – explained
Authors: Miličić T. , Sivasankaran M. , Blümner C. , Sorrentino A. , Vidaković-Koch T.
Published: March 2023

Periodic dynamic operation promotes CO faradaic efficiency. The key promoting parameters are the charge transfer coefficients of parallel reactions.
Adaptive particle patterning in the presence of active synthetic nanomotors
Authors: Xie Dazhi , Fu Shaoming , Fu Dongmei , Chen Bin , He Weidong , Liang Haiying , Tu Yingfeng , Wilson Daniela A. , Peng Fei
Published: March 2023

We propose an active Au–Zn nanomotor driven by water and discovered an interesting adaptive interaction mode of diffusiophoretic Au–Zn nanomotors with passive condensate particles in different environments.
Chemical constituents from Morus alba with proprotein convertase subtilisin/kexin type 9 expression and secretion inhibitory activity
Authors: Won Hongic , Son Min-Gyung , Pel Pisey , Nhoek Piseth , An Chae-Yeong , Kim Young-Mi , Chae Hee-Sung , Chin Young-Won
Published: March 2023

Twenty compounds were isolated from Morus alba using a PCSK9 expression monitoring assay. For the first time, it is found that betulinic acid may inherit a new role as a PCSK9 inhibitor.
Sustainable product-based approach in the production of olefins using a dual functional ZSM-5 catalyst
Authors: Sakha Mohsen Rostami , Halimitabrizi Parya , Soltanali Saeed , Ektefa Fatemeh , Hajjar Zeinab , Salari Dariush
Published: March 2023

Sustainable approach in the production of olefins using dual functional ZSM-5 catalyst in HTO and MTO processes.
Success stories of natural product-derived compounds from plants as multidrug resistance modulators in microorganisms
Authors: Zhai Xiaohan , Wu Guoyu , Tao Xufeng , Yang Shilei , Lv Linlin , Zhu Yanna , Dong Deshi , Xiang Hong
Published: March 2023

Microorganisms evolve resistance to antibiotics as a function of evolution. Antibiotics have accelerated bacterial resistance through mutations and acquired resistance through a combination of factors.
Cellulose-based sponge@ZIF-8 from waste straws for water disinfection
Authors: Li Jingyu , Zhang Yang , Sui Guoxin
Published: March 2023

ZIF-8 nanoparticles can be readily in situ generated on the skeleton surface throughout the entire structure of cellulose-based sponges obtained from waste corn straws via a hydrothermal process.
Supramolecular photosensitizers using extended macrocyclic hosts for photodynamic therapy with distinct cellular delivery
Authors: Zheng Xiuli , Lei Sheng-Nan , Gao Zekun , Dong Xiangyu , Xiao Hongyan , Liu Weimin , Tung Chen-Ho , Wu Li-Zhu , Wang Pengfei , Cong Huan
Published: March 2023

Two hydrophilic macrocycles can strongly bind hypocrellin B. The resulting supramolecular photosensitizers show excellent photodynamic efficiency with different cellular delivery.
Electrochemical response of surface-attached redox DNA governed by low activation energy electron transfer kinetics
Authors: Zheng Zhiyong , Kim Soo Hyeon , Chovin Arnaud , Clement Nicolas , Demaille Christophe
Published: March 2023

We demonstrate, using high scan rate cyclic voltammetry and molecular dynamics simulations, that the electrochemical response of electrode-attached redox DNA is governed by low reorganization energy electron transfer kinetics.
Rheological dynamics and structural characteristics of supramolecular assemblies of β-cyclodextrin and sulfonic surfactants
Authors: Bhat Bhargavi , Pahari Silabrata , Kwon Joseph Sang-Il , Akbulut Mustafa E. S.
Published: March 2023

Combining β-CD with sulfonic surfactants yielded a novel nanotubular architecture which enhanced the rheological properties in aqueous phases.
Gold nanoparticle-based two-photon fluorescent nanoprobe for monitoring intracellular nitric oxide levels
Authors: Arnau del Valle Carla , Thomas Paul , Galindo Francisco , Muñoz María Paz , Marín María J.
Published: March 2023

Highly-versatile two-photon fluorescent-nanoprobe for the detection of wide ranges of intracellular nitric oxide concentrations in macrophages, endothelial and cancer cells.
Development of double network polyurethane–chitosan composite bioinks for soft neural tissue engineering
Authors: Cheng Kun-Chih , Sun Yi-Ming , Hsu Shan-hui
Published: March 2023

Two double network composite hydrogels containing novel ternary soft segment-based biodegradable polyurethane (tPU) showed good biocompatibility, self-healing, and printability with high-resolution.
From highly oriented bulk black arsenic phosphorus to well-crystallized exfoliated flakes with enhanced anti-oxidation: precise control upon chemical vapor transport
Authors: Song Jiaqi , Chai Liyuan , Liang Yanjie , Wang Haiying , Lin Zhang , Liu Zhenxing , Liao Yi , Lai Xinting , Peng Cong
Published: March 2023

The consistent structure and high As atom substitution of highly-oriented b-AsP synthesized by precise control provided excellent anti-oxidation.
Speech and Language Characteristics of Neurologically Healthy Adults When Describing the Modern Cookie Theft Picture: Mixing the New With the Old
Authors: Hux Karen , Frodsham Kayla
Published: March 2023

Purpose:

The Modern Cookie Theft picture has recently become available. This study's purpose was to compare (a) speech and language production by neurologically healthy adults (NHAs) given a generic instruction to describe the picture versus instruction to describe it as if talking with someone who was blind and (b) production during the first 90 s versus full samples.

Method:

One hundred NHAs minus five outliers formed two participant groups. Each group heard either the original or modified task instruction. Transcriptions of resulting descriptions were analyzed regarding duration, word and T-unit productivity, content units (CUs), and main concepts (MCs) both in full and 90-s samples. Identified CUs and MCs were compared with existing lists from previous research.

Results:

Significantly longer samples and greater verbosity occurred with the modified versus original instruction even when limiting time to a 90 s maximum. With the modified instruction, CUs included 119 and 138 terms for truncated and full samples, respectively; participants mentioned 98 and 104 CUs, respectively, given the original instruction. MCs expressed were 18 and 19 for truncated and full samples, respectively, given the modified instruction; with the original instruction, this dropped to 11 and 12 MCs for truncated and full samples, respectively. Within samples, CU and MC repetitions were greater given modified rather than original instruction.

Conclusions:

Normative productivity and content generation data are critical for guiding diagnostic efforts and treatment planning. Benefits and detriments associated with differing productivity and content redundancy secondary to varying instructions and analysis time frames are discussed.
Sampling rate selection for multi‐loop cascade control systems in an optimal manner
Authors: Şuşcă Mircea , Mihaly Vlad , Dobra Petru
Published: March 2023

This article proposes an optimization‐based approach to selecting the sampling periods for classes of linear time‐invariant (LTI) regulators in a cascaded multi‐rate control structure, to account for practical implementation on numeric systems. Starting from the Shannon‐Nyquist sampling theorem, which proposes the minimum required sampling frequency for completely recovering the original analog signal from its discrete samples, the scope of the sampling process, viewed from a control perspective, is to ensure asymptotic stability of the closed‐loop system, with the smallest possible degradation of the initially‐proposed performance indices as possible according to a set of well‐picked criteria. As such, a configurable optimization‐based approach is proposed, solved with the mixed‐integer artificial bee colony (MI‐ABC) algorithm, for selecting the sampling periods by specifying the emphasis between closed‐loop fidelity and ease of implementation, with an intuitive visualization method. The proposed solution is illustrated on two case studies, with emphasis on the construction of the proposed functionals and their practical implications.
Forward modelling of brightness variations in Sun-like stars
Authors: Nèmec N.-E. , Shapiro A. I. , Işık E. , Solanki S. K. , Reinhold T.
Published: March 2023

Context. The amplitude and morphology of light curves of Sun-like stars change substantially with increasing rotation rate: brightness variations are amplified and become more regular. This has not been explained so far.

Aims. We develop a modelling approach for calculating brightness variations of stars with various rotation rates and use it to explain the observed trends in stellar photometric variability.

Methods. We combined numerical simulations of magnetic flux emergence and transport with a model for stellar brightness variability to calculate synthetic light curves of stars as observed by the Kepler telescope. We computed the distribution of the magnetic flux on the stellar surface for various rotation rates and degrees of active-region nesting (i.e. the tendency of active regions to emerge in the vicinity of recently emerged regions). Using the resulting maps of the magnetic flux, we computed the rotational variability of our simulated stellar light curves as a function of rotation rate and nesting of magnetic features and compared our calculations to Kepler observations.

Results. We show that both the rotation rate and the degree of nesting have a strong impact on the amplitude and morphology of stellar light curves. In order to explain the variability of most of the Kepler targets with known rotation rates, we need to increase the degree of nesting to values that are much higher than the values on the Sun.

Conclusions. The suggested increase in nesting with the rotation rate can provide clues about the flux emergence process for high levels of stellar activity.
Enhancing postharvest quality of fresh-cut plums with chitosan-grape seed oil edible coatings
Authors: Zsivanovits Gabor , Sabeva Petya , Iserliyska Dida , Zhelyazkov Stoil , Parzhanova Albena , Nesheva Marieta
Published: March 2023

Edible coatings are traditionally used to improve food appearance and conservation due to their environmentally friendly nature. In this study fresh cut (halved and pitted) plum (var. Stanley) fruits were coated by chitosan grape-seed-oil (GsO) nanoemulsion. Physical, physico-chemical, microbiological and sensorial properties were examined 3 times during 9 d refrigeration storage. The control probes wasted their safety and quality after the 4th d. The coated probes preserved their quality and safety to the end of the storage period. The fruits with chitosan coating showed smaller microbiological contamination but the chitosan GsO coated fruits showed higher values in the sensorial parameters. The coated samples preserved their sensorial parameters up to 80% on the 9th d.
Determination of histamine levels in fresh fish using Near Infrared (NIR) technology
Authors: Kitanovski Vladimir , Demiri Sani
Published: March 2023

Fresh fish and fish products are highly perishable food. Development of fast, secure and non- destructive technique for estimation the presence and quantity of components which are related with safety of food products is of great interest for science but also and for the industry sector. Above-mentioned idea is the aim of this research work, precisely, determination of histamine levels in fresh fish with the use of different near infrared handheld devices. Histamine is one of biogenic amines among putrescine, cadaverine, tyramine which are non-volatile amines produced post mortem and are formed from decarboxylation of specific free amino acids in fish or shellfish tissue. Reason why we choose to developing technique for evaluation of histamine levels is EU Regulation 2073/2005 requires the determination of histamine at three different levels: 100, 200 and 400 mg/kg. For reaching the goal we decided to use paper-based technology for collecting samples for evaluation using Whatman grade 2 qualitative filter papers. In the first phase for validation of NIR devices specifications, and for creation of calibration curve we used histamine solution with 0.5, 1, 2.5 and 5 %. Results showed regression of R2 = 0.69 which indicates that NIR devices can be promising tools for spotting histamine beside small molecular weight.
Investigation of cold cracking resistance of HSLA 950A steel by taguchi optimization technique
Authors: Velumani Manivel Muralidaran , Krishnasamy Senthilkumar , Ramanathan Seranthian , Subramanian Chidambaram
Published: March 2023

Cold cracking is one of the major issues during welding High Strength Low Alloy (HSLA) 950A steel. The aim of the present research work is to optimize preheating temperature, the addition of oxide particles, and heat input using the Taguchi design of experiments for bead on plate, especially on the improved impact strength of weld metal. The experiments are carried out at three levels of mentioned parameters and Charpy impact strength is considered as a response. L27 orthogonal array is selected for experimentation in the present investigation using three parameters. An addition of vanadium oxide (V2O5) has acted as a nucleation site for acicular ferrite and enhanced the cold cracking resistance of investigated steel. The experimental results suggested that the impact strength of weldment is strongly influenced by pre-heating temperature (74.5%) and less influenced by oxide particle concentration (12.7%), and heat input (12.2%). Microstructure at HAZ revealed the presence of a small proportion of acicular ferrite of Widmanstatten morphology and upper bainite near weldment causes the reason for enhancement in cold cracking resistance. Fractographic examination revealed the presence of both ductile and brittle fracture modes, which attributed to higher and lower impact strength of weld joint respectively.
The changing concept of enlightenment in Russia – An outline
Authors: Dmitrieva Nina A.
Published: March 2023

At the end of the twentieth and the beginning of the twenty-first century there is a widespread renewal of interest in the “Project Enlightenment” and its relevance for the present day. The subject has rarely been touched upon in Russia. However, the concept “enlightenment” can be found in Russian present-day public discourse. Here the different Russian traditions in the interpretation of enlightenment are taken up once more. The changes and modifications of the concept “enlightenment” in Russian intellectual history lead to an understanding of the discourse of enlightenment in contemporary Russia. First of all, I sketch the most significant stages in the history of the concept of enlightenment in Russia. Important in this context is an anti-enlightenment campaign initiated and supported by the Tsar and the Church which claimed the concept of enlightenment as its own. A continuation of this movement can be found in some areas of contemporary public discourse which are essentially controlled by representatives of the Church. On the other hand, one finds in the media popular presentations of up-to-date scientific research where the principles of modern rationality and their importance for a culture of humanity are excluded. I show also the place of Kant’s philosophy in this tradition and conclude with a thesis concerning the prospects of the “Project Enlightenment” in Russia today.
The system model of argumentation in a comparative study of texts by Kant and Solovyov
Authors: Popova Varvara S. , Pushkarsky Anatoly G.
Published: March 2023

There is a noteworthy methodological approach which is based on the system model of argumentation (SMA) proposed by V.N. Bryushinkin. Argumentation theory is used to reconstruct the implicit presuppositions of philosophical systems or their fragments. The results of a comparative analysis of philosophical and legal texts by Immanuel Kant and Vladimir Solovyov are presented as well as the reconstruction of their world models performed by Bryushinkin using the SMA. A summary is given of Bryushinkin’s reconstruction of Kant’s and Solovyov’s arguments concerning the law of retribution (the death penalty). The SMA methodology is shown to highlight differences between the views of the two philosophers on the death penalty, rooted in variations between their world models. Bryushinkin’s reconstruction of the world models of Kant and Solovyov, based on fragments of their texts on specific problems of the philosophy of law (punishment and retribution, the death penalty), provides insights into their fundamental ideas on relations between society and the individual and the values underlying these relations. The SMA seems an elegant and rational methodological tool for philosophical text interpretation. We introduce the concepts of world model and philosophical thinking style to describe unique ways to express meanings in a text.
Kant on free thinking and its boundaries
Authors: Ivanov Mikhail A.
Published: March 2023

The concept of “free thinking” in the context of Kant’s philosophy presents a theoretical and practical problem. Kant applies the concept of freedom primarily to practical reason and moral philosophy, but elements of freedom (in thinking) can be identified in other sections of his teaching. Free thinking, according to Kant, can be interpreted as thinking activity conducted in the absence of any prerequisites, utmost unboundedness and independence, but having definite boundaries in various areas. The analysis of this ambivalence of free thinking is carried out in such sections of Kant’s teaching as theoretical knowledge, the area of everyday thinking, the social field and the work of artistic genius. One of the tendencies revealed as a result of this analysis is Kant’s desire to postulate the unconditionality of the freedom of thought in different areas, and then to formulate minimum constraints on it. Thus, while proclaiming unlimited freedom “to use his mind and speak on his own behalf” in the social sphere, Kant admits only two restrictive principles: the requirement of scientific knowledge and the presence of goodwill. The most important component of free thinking in the teachings of Kant is the principle of sapere aude, which acts as the trigger-mechanism and the foundation of free thinking, as well as the evidence for its sociality and non-mechanistic nature. Research shows that, through the concept of free thinking, Kant implicitly formulates the ideal of free thinking, which manifests historical continuation and has lasting value.
Kant on sex and gender. Or: Is femininity only education?
Authors: Pape Carina
Published: March 2023

Much has been written about Kant’s misogyny. His remarks about the “Geschlechtscharaktere” (features of the sexes) have been interpreted as evidence of his negative attitude towards women. Most of these comments on “women’s nature” overlook the fact that Kant used the term “nature” differently, depending on the focus of each writing. Such a focus might be empirical, transcendental or pragmatic. In fact, Kant described “masculine” and “feminine” as social categories in the sense of twentieth-century gender concepts that assume a biological sex and a cultural or social gender. A small side-note on whether “femininity is only education or a natural disposition” illustrates Kant’s awareness of these categories and the importance of socio-cultural influences. In his opinion, both sexes can exceed both gender ideals, the feminine and the masculine, and thus present a distorted picture of the respective gender ideal – independently of the biological sex. I will show that Kant advocated a degree of freedom regarding gender identity and thus foreshadowed the gender theories developed in the late twentieth century, which are heteronormative but not essentialist.
Immanuel Kant as the first epistemological constructivist
Authors: Danielyan Naira
Published: March 2023

According to constructivism-theory, the object of a cognition process is a question which the subject has not answered yet. The subject is not able to retrieve the answer from his memory through direct observations, by reading books or by asking specialists. However, it forms an objective field through reasoning. It is a relatively narrow circle of phenomena, relating to the search for an answer to a cognitively significant question. Cognition serves to organise the subject’s experimental activity, but it does not discover any ontological reality. Here the question of correspondence of the knowledge received by the subject to an object is immediately raised. Kant tried to answer it, having separated the spheres of theoretical and practical mind applications. The sphere of the rational was thus moved to the subject and human activity. Kant’s argumentation contains two steps: 1) previous attempts to coordinate knowledge and the object were in vain; 2) many scientists of early modern Europe took into consideration the correspondence of the object to the knowledge gained. Kant concludes that subjective perceptional and empirical contemplation fill a cognised object with sense and meaning. The subject of cognition transcends experimental limits and lies on the ulterior side of knowledge. Concerning the cognition process, Kant defines a demand for the reality of the knowledge obtained as a stipulated consequence resulting from a number of evidences. This article illustrates these ideas in relation to epistemological constructivism from the position of modern scientific and technological progress as they play a leading part in it.
Réflexions théoriques et méthodologiques autour du concept de fatigue cognitive
Authors: Mangin Thomas , Audiffren Michel , André Nathalie
Published: March 2023

Au quotidien nous réalisons des tâches cognitives qui requièrent de l’effort. Quand ces tâches sont particulièrement longues et/ou difficiles, elles induisent généralement de la fatigue cognitive. Cette dernière entraîne une baisse des performances qui s’accroît au cours du temps passé sur la tâche et s’observe dans des tâches subséquentes. Bien que ce champ de recherche soit très prolifique avec des centaines d’études publiées chaque année, l’existence de l’effet délétère de la fatigue cognitive sur la performance ainsi que les mécanismes explicatifs qui sous-tendent cet effet sont encore en débat. Cet article présente dans un premier temps la distinction entre le concept de fatigue cognitive et différents concepts proches tels que ceux de fatigue centrale, de fatigue physique ou encore d’ennui. Par la suite, les grandes théories explicatives de la fatigue cognitive sont abordées, ainsi que leurs divergences et convergences. Les méthodologies employées pour étudier la fatigue cognitive sont aussi explorées, ainsi que les variables confondantes qui doivent être contrôlées lors de la réalisation d’études sur ce sujet. Enfin, les perspectives pour les recherches futures sont explorées notamment les synergies entre les théories explicatives, les moyens de lutter contre la fatigue cognitive aiguë ou encore les pathologies qui peuvent accentuer la fatigue cognitive.