bluuebunny/crossref_metadata_2025 huggingface dataset:
Pemanfaatan Limbah Industri dan Pertanian sebagai Pakan Suplemen Ternak Sapi Bali untuk Meningkatkan Pendapatan Peternak
Authors: Syarifuddin  , Firmiaty Sri , Azuz Faidah , Wati Yenny , Widaryanti
Published: June 2024

Sapi Bali (Bos indicus) merupakan ternak ruminansia salah satu plasma nutfah asli Indonesia, yang banyak dipelihara di seluruh wilayah Indonesia termasuk di pedesaan Sulawesi Selatan. Pakan basal ternak ruminansia adalah hijauan, namun terbatas ketersediaanya sepanjang tahun, terutama di musim kemarau. Kebutuhkan pakan sapi dapat juga diberikan dari limbah industri dan pertanian yang diperoleh dari lingkungan sekitar. Limbah industri berupa molasses, ampas tahu, dedak, bungkil kelapa dilengkapi garam dan mineral mix dapat diolah menjadi pakan suplemen. Molasses, ampas tahu, dedak, bungkil kelapa, garam dan mineral mix (komposis tertentu) dihomogenkan dan disatukan dengan sumber serat (perbandingan 40%:60%) selanjutnya difermentasi selama 21 hari. Pelatihan pembuatan pakan suplemen telah dilakukan kepada kelompok tani ternak Coppo Bulu di Desa Bulo, Kecamatan Pancarijang, Kabupaten Sidenreng Rappang, Sulawesi Selatan. Dengan demikian pakan akan tersedia sepanjang tahun, limbah tidak mencemari lingkungan dan PBB Bali jantan dengan pakan ini berdasarkan hasil penelitian yang telah dilakukan adalah 0.8-1.5 kg/ekor/hari sehingga berefek positif terhadap peningkatan pendapatkan peternak. Setelah mengikuti pelatihan ini petani ternak memahami dan mampu membuat sendiri pakan tambahan, menggunakan limbah pertanian dan limbah industri.
Sosialisasi Perilaku Hidup Bersih dan Sehat Untuk Anak PAUD
Authors: Manuntungi Andi Erna , Sriyanti Febri , Wahyuni Ayu Sri
Published: June 2024

Perilaku Hidup Bersih dan Sehat (PHBS) merupakan konsep yang penting untuk diterapkan di lingkungan individu maupun keluarga. Namun, masih banyak anak usia dini yang belum memahami konsep PHBS dengan baik. Oleh karena itu, tujuan dari pengabdian masyarakat ini adalah untuk memberikan sosialisasi PHBS kepada anak PAUD di TK Al Quba Mamuju. Metode pelaksanaan yang digunakan adalah dengan memberikan materi PHBS dan praktek mencuci tangan yang baik dan benar secara kolaborasi antara pemateri dan peserta. Hasil dari kegiatan ini menunjukkan bahwa peserta mampu memahami konsep dasar PHBS dan tata cara mencuci tangan yang baik dan benar pasca pandemi. Selain itu, peserta juga mampu memberikan umpan balik yang baik terhadap materi yang diberikan. Kesimpulan dari kegiatan ini adalah bahwa pengabdian masyarakat dalam bentuk sosialisasi PHBS dapat memberikan manfaat bagi anak PAUD dalam meningkatkan kesehatan dan kualitas hidup mereka.
Pengelolaan lingkungan pesisir melalui gerakan bersih pantai dan optimalisasi pos siskamling di kawasan wisata sungai pisang
Authors: Khatimah Husnil , Utami Dinny Salfiyah , Pransiska Pransiska , Faradila Putwi Ayu , Hazirin Tasya Humaira
Published: June 2024

Permasalahan yang terjadi di Kawasan Sungai Pisang yaitu pencemaran lingkungan dan pos siskamling yang kurang terawat. Pencemaran lingkungan ini, khususnya dari sampah plastik dapat merusak ekosistem pesisir pantai. Selain itu, masalah pos siskamling di kawasan Sungai Pisang yang tidak layak karena kondisi papan yang lapuk dan cat pada papan yang memudar. Tujuan pengabdian kepada masyarakat adalah untuk mewujudkan lingkungan yang bersih di kawasan Sungai Pisang sehingga dapat memberikan dampak positif seperti kesehatan masyarakat dan memberikan kenyamanan saat melaksanakan kegiatan siskamling. Metode pelaksanaan adalah melakukan survei lokasi, melaksanakan pembersihan dan perbaikan, pelaksanaan sukses dan hasil sesuai tujuan. Kegiatan diawali dengan survei lokasi kemudian dilakukan pembersihan pantai dan memperbaiki pos siskamling. Berdasarkan hasil kegiatan pengabdian kepada masyarakat, bentuk partisipasi masyarakat dalam peningkatan kualitas lingkungan dilaksanakan melalui sistem keamanan, ketertiban, dan kebersihan lingkungan. Selain itu, para pemuda di desa tersebut juga ikut serta memperbaiki posko tersebut.
Legalitas dan digitalisasi umkm blangkon pacul gowang dan pakaian adat di Desa Sawocangkring Sidoarjo untuk mendukung SDGs
Authors: Wijaya Sonny , Afifah Yulita Dwi Nor , Permana Oky , Muzzaky Muhammad Alfian , Fazriyah Laily , Saputra Mochamad Fahmi , Lestari Lilla Puji
Published: June 2024

Program pengembangan usaha mikro, kecil dan menengah (UMKM) di Desa Sawocangkring, Jawa Timur, bertujuan untuk mendukung pertumbuhan berkelanjutan dan berkontribusi terhadap tujuan pembangunan berkelanjutan (SDGs). Legalitas dan digitalisasi menjadi fokus utama yang didukung oleh penyediaan peralatan produksi. Kegiatan pengabdian masyarakat ini dilakukan oleh mahasiswa Kuliah Kerja Nyata (KKN) Universitas Ma’arif Hasyim Latif (UMAHA) Sidoarjo pada tanggal 1 Agustus sampai 31 Agustus 2023 di dusun Cangkring, desa Sawocangkring, Wonoayu, Sidoarjo, Jawa Timur dan UMKM yang dipilih adalah usaha blangkon pacul gowang merk ‘Abdul Rosid’ dan usaha pakaian adat merk ‘Ma’ruf’. Metode yang digunakan untuk kegiatan pengabdian masyarakat ini dengan kualitatif yaitu observasi lapangan dan wawancara ke pemilik UMKM sampai pada permasalahan yang dihadapi. Hasilnya kegiatan pengabdian masyarakat ini dari aspek legalitas diwujudkan melalui penerbitan izin Nomor Induk Berusaha (NIB) yang memungkinkan akses platform e-commerce. Program ini juga memberikan pelatihan pemanfaatan media sosial dan platform e-commerce bagi UMKM termasuk memberikan bantuan peralatan dan mesin yang bisa menunjang produksinya. Dengan tetap eksisnya UMKM diharapkan menjadi agen perubahan positif dan berkontribusi terhadap tujuan SDGs.
Sosialisasi Pentingnya Melanjutkan Pendidikan Ke Sekolah Menengah Atas Pada Siswa SMPN 37 Padang di Kelurahan Sungai Pisang
Authors: Khatimah Husnil , Lovery Nathasya , Irfani Luthfia
Published: June 2024

Beberapa faktor seperti ekonomi, dukungan orang tua dan jarak tempuh sekolah merupakan penyebab rendahnya minat siswa untuk melanjutkan sekolah di Kelurahan Sungai Pisang. Tujuan pengabdian kepada masyarakat ini adalah untuk memberikan sosialisasi pentingnya pendidikan bagi siswa yang berada di Sekolah Menengah Pertama agar dapat melanjutkan pendidikan ke Sekolah Menengah Atas bahkan perguruan tinggi. Kegiatan Sosialisasi ini dilakukan pada tanggal 11 Juli 2023. Sasaran dalam pengabdian ini adalah siswa kelas IX SMPN 37 Padang yang bertempat di Kelurahan Sungai Pisang.  Metode yang digunakan memberikan penyuluhan dan tanya jawab tentang minat dan motivasi melanjutkan pendidikan ke tingkat yang lebih tinggi, khususnya tingkat SMA. Berdasarkan hasil  tanya jawab yang dilakukan sebelum sosialisasi dan penggunaan kuisioner sesudah sosialisasi terlihat adanya peningkatan sebesar 51.85%. Persentase siswa yang ingin melanjutkan pendidikan ke jenjang SMA sebelum sosialisasi sebesar 37.04% dan mengalami peningkatan menjadi 88.89%. Hal ini menandakan minat dan motivasi siswa bertambah setelah mengikuti sosialisasi.
Sosialisasi Pencegahan dan Penanggulangan Stunting di Kelurahan Teluk Kabung Selatan
Authors: Khatimah Husnil , Ramadina Mutia , Malta Rahmadini
Published: June 2024

Stunting merupakan permasalahan yang dihadapi balita akibat terganggunya penyerapan nutrisi sejak kehamilan, baik bagi ibu hamil maupun balita, sehingga dapat menghambat tumbuh kembang anak dan menyebabkan dampak negatif jangka panjang. Teluk Kabung Selatan, Sungai Pisang merupakan salah satu kelurahan yang memiliki anak stunting dan masih banyak masyarakat yang belum paham dengan stunting yang mempengaruhi pertumbuhan dan perkembangan anak. Tujuan kegiatan pengabdian untuk memberikan sosialisasi dan edukasi kepada masyarakat mengenai pencegahan dan penanggulangan stunting di Kelurahan Teluk Kabung Selatan. Metode yang digunakan merupakan metode pengajaran ditaktik yang dilakukan dengan mengajarkan berbagai pengetahuan melalui pemberian informasi mengenai pencegahan dan penanggulangan stunting. Hasil dari kegiatan sosialisasi ini ternyata memberikan dampak positif terhadap masyarakat. Kegiatan sosialisasi yang dilakukan mampu meningkatkan pemahaman masyarakat sebesar 30%. Rata-rata pengetahuan masyarakat dalam pencegahan dan penanggulangan stunting sebesar 80% setelah dilakukan sosialisasi.
Edukasi Pemanasan Global dan Dampaknya Terhadap Ekosistem Pantai di Pulau-Pulau Kecil Bagi Pelajar SMA Negeri 11 Ambon
Authors: Kesaulya Irma , Rahman Rahman , Krisye Krisye , V. T. Soukotta Imanuel
Published: June 2024

Pemanasan global merupakan isu penting bagi semua negara di dunia karena memberikan dampak negatif bagi masyarakat dunia dan juga semua organisme di darat dan laut. Generasi muda saat ini perlu mengetahui dengan jelas dan benar apa yang dimaksud dengan pemanasan global, faktor penyebab terjadinya pemanasan global dan usaha-usaha yang harus dilakukan untuk mengurangi laju proses pemanasan global yang terjadi saat ini. Tujuan dari program Pengabdian Kepada Masyarakat ini adalah mengedukasi generasi muda khususnya siswa SMA negeri 11 Ambon tentang pemanasan global dan dampaknya bagi kehidupan manusia. Metode yang digunakan dalam melaksanakan program Pengabdian Kepada Masyarakat ini adalah dengan cara pre test, penyajian materi, diskusi, tanya jawab dan post test. Hasil analisis dari pre test dan post test menunjukan hanya 32%  siswa yang memberikan jawaban yang benar saat pre test dan saat post test mengalami peningkatan menjadi 55%. Hal ini menunjukan bahwa kegiatan sosialisasi ini memberikan dampak peningkatan pengetahuan siswa tentang pemanasan global. Kegiatan PkM harus terus ditingkatkan implementasinya kepada siswa di semua jenjang mulai dari sekolah dasar sampai dengan sekolah menengah atas di pulau-pulau kecil di provinsi Maluku. Hal ini akan meningkatkan pengetahuan generasi muda tentang pemanasan global dan hal ini dapat menjadi salah satu metode untuk memperlambat proses pemanasan global yang terus terjadi saat ini.
Kekerabatan Zeylanicobdella arugamensis pada Ikan Kerapu Cantang dengan Pendekatan Molekuler di Jawa Timur dan Lombok
Authors: Ochtavia Sherly , Mahasri Gunanti , Mufasirin Mufasirin
Published: June 2024

Giant grouper is a highly sought-after cultivated fish in Indonesia due to its high market value. One of the challenges in grouper aquaculture is the infestation of the sea leech ektoparasite Zeylanicobdella arugamensis. The prevalence rate of ektoparasite infestation reaches up to 100%. An effective method to manage ektoparasite infestation is through molecular profiling, serving as preliminary literature in the development of molecular biology efforts to overcome cultivation challenges in giant grouper. This research aims to study the homology and relationship of Zeylanicobdella arugamensis on giant grouper in East Java, specifically in Lamongan, Mandangin, Situbondo, and Lombok. The method used is RT-PCR with mtDNA COI gene primers. Molecular sequence data were collected from samples and compared with data from NCBI GenBank, and analyzed using Neighbor-joining phylogenetic tree method and homology data analysis on BLAST. The research results indicate clinical symptoms in giant grouper including swelling, lesions/wounds, pale skin, decreased appetite, and fin erosion. Electrophoresis results from PCR products show a single band at 750bp for samples from Lamongan, Situbondo, Mandangin, and Lombok. DNA sequencing results on NCBI BLAST and homology analysis against the reference gene were conducted. Homology analysis results between samples from Situbondo and Lamongan show the highest similarity at 98.28%, whereas the lowest similarity is between samples from Mandangin and Situbondo at 88.51%. Based on phylogenetic tree analysis, samples from Lamongan and Situbondo waters show a close relationship with a genetic distance of 0.009272.
What Is Love? A Factor Analysis of Established Frameworks and a Semantic Analysis of Individual Western Beliefs
Authors: Reyes-Fournier Elizabeth , Reyes-Fournier Paul , Reyes-Fournier Robert
Published: June 2024

The assessment of the construct of love has been attempted with various self-reporting questionnaires but there is no evidence that these measures are assessing the same construct. This research is attempting to develop a culturally sensitive definition for the construct of love. This research is a two-part study. The first part of the research sets out to validate eight of the widely used love (or related area) self-reporting measures. We hypothesized that there would be high collinearity between the various measures and that they would be related to the individual’s perception of love. 565 adults were surveyed and were given each of the love measures, demographic questions, an overall rating of love (0-100), as well as an open-ended question to explain their definition of love. Factor analysis revealed that several of the measures had more factors than they reported, the items were plagued with high collinearity, or they had items that did not meet the minimum threshold for model inclusion. The second study addressed the attitudes toward love in Western society using an Implicit Association Test (IAT). We hypothesized that cognitive load would vary by the categorizations of love words. 1102 individuals in the United States and Europe were given a list of 158 words and asked if the word was associated to love or not love while cognitive load, measured as latency, was recorded. The results indicated that love words are identified faster than not love words. Conclusions are consistent with Prospect Theory and the Theory of Constructed Emotions.
Limited McDonaldization as a Success Recipe: An Ethnographic Study of Yili Driving School in Jinan, China
Authors: Ping Shu
Published: June 2024

Current corporate culture studies mainly emphasize the management and motivation of employees within an enterprise, while little consideration is taken of the interaction between the enterprise, employees and customers. Based on an ethnographic study of Yili Driving School in Jinan, this article explores the success recipe of service-oriented enterprises. It argues that the success of the driving school can be attributed to its corporate culture of limited McDonaldization, consisting of two contradictory but coexisting models, i.e. a rationalized and standardized management model and a relational and emotional work model, in which corporate management, employees and consumers are all involved. So far as the driving school is concerned, the school administrators, coaches and students selectively use cultural resources to adopt different action strategies which enable the participants of the corporate culture to achieve a win-win situation. This study highlights not only the McDonaldized management of the enterprise, but also the mechanism of emotional cultivation between the driving school, instructors and trainees. The result of this study is hoped to contribute to research on corporate culture and enterprise anthropology by breaking with the previous approaches from within the company.
Proactively Addressing New Teacher Retention and Attrition During the Senior Year: A Comprehensive Course Redesign
Authors: Sumowski Robert F.
Published: June 2024

After being named a 2022-2023 Georgia Governor’s Teaching Fellow, the author was asked to identify a course or a project that would be the focal point of his work during the year-long series of monthly symposia that constituted the program. The program enabled the author to conduct a comprehensive redesign of a relatively outdated course. The course, entitled EDEX 4334: Teachers as Leaders, was transformed into a relevant, real-world educational experience designed to address the issues of teacher attrition, retention, and burnout using activities designed to enhance the experience of undergraduate Special Education majors at Georgia College & State University. The result was a reimagined course that incorporated components addressing key issues facing new teachers such as navigating the hiring process, resume preparation, rehearsing the interview processes, handling Special Education IEPs and caseloads, managing paraprofessionals, supervisors, and colleagues, honing time management skills, and addressing self-care in order to prevent new teacher attrition and burnout.
Mapping Melmoth: Charles Robert Maturin in/and the World Republic of Letters
Authors: Morin Christina
Published: June 2024

This article offers a transnational mapping of Melmoth the Wanderer (1820) that links fictional narrative both to the contexts of its production and dissemination in a global literary marketplace and to its network of influence, and more particularly, its reputation and afterlife within what Pascale Casanova has influentially called ‘the world republic of letters’. It first considers Melmoth’s internal geography and the novel’s use of space in relation to Maturin’s quest for ‘literary capital’. 1 It then expands upon, in Casanova’s terms, Melmoth’s ‘ littérisation’, namely, the process by which, in spite of its often-unfavourable contemporary reception, Melmoth was transformed from a state of ‘literary inexistence to existence’ via translation and adaptation. 2 Finally, it explores Northern Irish Big Telly Theatre Company’s 2012 dramatic adaptation as evidence of Melmoth’s littérisation.
Melmoth and the Irish Gothic Tradition
Authors: Potter Madeline
Published: June 2024

This article explores the legacies of Melmoth, the title character of Charles Maturin's Melmoth the Wanderer (1820), in the context of the Irish Gothic tradition. I argue that Melmoth's corporeal monstrosity is symbolically reified in subsequent texts, and that consequently Irish Gothic fiction is both possessing of and possessed by Melmoth. Exploring this in-between space where Melmoth is re-fashioned and re-imagined, I ask what this means for the Irish Gothic tradition and the processes of reflection and self-reflection these texts enact. I therefore trace Melmoth's influence by surveying the works both of Anglo-Irish writers and of Irish Gothic writers outside this particular tradition. In particular, my argument examines tropes of doubling and mirroring in such texts so as to highlight Melmoth's presence as a symbolic and semiotic revenant.
Catherine Malabou’s Historical Epistemology
Authors: Barnett Tobias
Published: June 2024

This article seeks to address what the work of Catherine Malabou can offer to the thinking and understanding of history. Characterizing Malabou’s intellectual project as a meditation on the relation between history and possible knowledge, it situates the philosopher’s work in the tradition of historical epistemology. It will be argued that, in its engagement with philosophical and (neuro)biological theories of plasticity and epigenesis, the historical constitution of Malabou’s philosophical system problematizes the practical and ontological difficulty behind any commitment to a historically bounded knowledge of what here will be called, following Heidegger and Foucault, ‘pure finitude’. The article concludes by suggesting that, if placed alongside the work of intellectual historian Quentin Skinner, Malabou’s historical epistemology makes a decisive and useful contribution to contemporary debates regarding historical method by underscoring the (neuro)biological rooting of persistent epistemic gaps between historical understanding and experience.
Automatisering av ekonomiskt bistånd
Authors: Stranz Hugo , Germundsson Nora , Hussénius Klara , Bergmark Åke
Published: June 2024

Standardising the Last Welfare Safety Net? RPA-support in Practical Work with Social Assistance in Sweden
In recent years, the use of digital support systems in the administration of Swedish social assistance (SA) has become increasingly widespread. Current surveys show that around 10 percent of Swedish municipalities make use of so-called Robot Process Automation (RPA) in their everyday practice. As key arguments for the use of RPA-support, aspects such as unburdening employees of pure administrative tasks, as well as increased transparency and enhanced legal certainty for applicants, are often highlighted.
The present paper presents results from a larger research project addressing the practical use of RPA-support in Swedish Personal Social Services. The analyses are based on cross-sectional quantitative data from 800 cases collected in four medium-sized Swedish municipalities. Half of the cases reflect assessment outcomes before RPA-support was implemented; the other half show outcomes after implementation. The paper aims, first, to describe the character and contents of the different RPA-tools utilised in municipalities. Second, the paper aims to describe and analyse the outcomes of SA decisions before and after the implementation of RPA-support, respectively.
Our main findings are as follows: (a) while RPA can partially alleviate the administrative burden on social workers, human involvement remains essential for individual assessments; (b) even though the use of RPA-support does not establish any significant relation to the outcomes of SA eligibility assessments, the assessments are far less generous after the implementation of RPA than before; and (c) the changes in generosity are particularly notable with regard to applications outside of the National Benefit Standard, which is a strong predictor for the rejection of applications.
Digital infrastruktur och socialtjänstens myndighetsutövning i Sverige
Authors: Svensson Lupita , Ranerup Agneta
Published: June 2024

Digital infrastructure and the exercise of authority by social services: the case of social assistance in Sweden
This article explores how digitalisation impacts the discretionary space and decision-making processes of social workers in the administration of social assistance within social services. In the context of increasing digitalisation and automation in public administration, the study examines the complex dynamics between human and non-human actors, such as social workers, clients, and digital systems like RPA (Robotic Process Automation) and e-application platforms. Drawing on theories such as Actor-Network Theory (ANT) and concepts of digital discretion and professional discretionary space, the article investigates how digital infrastructures and systems shape social workers' practices and their relationships with clients.
Utilising a qualitative methodology comprised of document analysis and semi-structured interviews with social workers in three Swedish municipalities, the study maps out "data journeys" – the process by which human activities are converted into, and interact with, digital data flows within case management systems. The results indicate that digital technology both challenges and enriches the practice of social work by transforming traditional work processes and client interactions, while new forms of professionalism and citizen participation emerge.
The study highlights both the potential and challenges of integrating digital technology into social work. It underscores the importance of a balanced and critically aware approach to digitalisation, where the role and impact of technology are continually reassessed in light of professional values and clients' needs. Future research should continue to explore the dynamic relationship between digital technology and social work to ensure that digitalisation supports, rather than undermines, the fundamental goals and values of social services.
La perspectiva en la episteme artístico-científica de Leonardo Da Vinci
Authors: GUZMAN MUÑOZ LILIANA JUDITH
Published: June 2024

El ensayo desarrolla la conjetura según la cual la utilización de la idea de “perspectiva” en la obra de Leonardo Da Vinci es una de las epistemes por las cuales aún podemos considerar nuestra modernidad. En el dispositivo científico y artístico de la obra de Leonardo Da Vinci es clave la utilización de la perspectiva, para su obra como también para el abordaje del conocimiento, la investigación y el arte de su tiempo. Precisamente, por haber inaugurado el Renacimiento no sólo el horizonte de la ciencia empírica moderna sino también su apropiación del legado cultural desde una mirada antropocéntrica y humanista, quizás por ello la modernidad aún mantiene plena vigencia en nuestra época, especialmente por la vigencia de la perspectiva en el arte contemporáneo de la imagen.
ALQUIMIA DA IMAGEM
Authors: Fier Lucas
Published: June 2024

A colagem representa para o Surrealismo tanto uma técnica artística, comum no contexto das vanguardas, como um elemento fundamental da sua poética para a composição das imagens, que encontram sua potência na aproximação entre duas ou mais realidades distintas e incompatíveis. Definida por Max Ernst como “alquimia da imagem visual”, o efeito visado da colagem surrealista é o curto-circuito da percepção comum, capaz de criar um estranhamento frente à vida cotidiana e habitual. O presente trabalho tem como objetivo propor uma relação da colagem surrealista com o conceito de melancolia apresentado por Walter Benjamin, compreendendo-a como procedimento alegórico, e analisar a sua conexão com a “organização do pessimismo” enquanto “melancolia revolucionária”.
Alimentación exigente en niños; signos y síntomas, evaluación e intervención multiprofesional
Authors: Espitia Rojas Gleidy Vannesa , Romero Gordillo Maria Alejandra
Published: June 2024

Los trastornos por evitación/restricción de la ingesta, han sido ampliamente descritos por la similitud en sus características y las consecuencias que estas traen sobre el desarrollo y crecimiento de los niños que lo experimentan.  La alimentación exigente es un trastorno de tipo multifactorial, en donde los niños muestran comportamientos negativos frente a la comida o tienen preferencia por un grupo de alimentos. Esta revisión narrativa de la literatura tiene como objetivo presentar las últimas investigaciones relacionadas con la alimentación exigente, ofreciendo una guía sobre signos y síntomas, evaluación e intervención en los niños con alimentación exigente realizada por el equipo multiprofesional.
 La revisión de literatura fue conducida en las bases de datos PubMed y Scopus, aplicando como principal criterio de inclusión artículos en inglés, español y portugués, sobre alimentación exigente en niños entre el nacimiento y los 5 años. Los resultados de esta revisión apuntan que la alimentación exigente estaría determinada por tres estadios importantes en la vida del niño; la gestación, la fase temprana de alimentación y las experiencias durante su segundo año de vida, por lo tanto, se requiere reconocer las señales de alerta (rechazo a comer determinados alimentos, falta de habilidades para alimentarse, duración excesiva durante los tiempo de alimentación etc.,), lo que permite realizar una evaluación temprana, que guie la intervención terapéutica, favoreciendo así una alimentación segura y eficaz para la nutrición y calidad de vida del niño.
El incremento de las alteraciones auditivas en población infantil: una revisión narrativa
Authors: Cano-Villagrasa Alejandro , López-Zamora Miguel , Porcar-Gozalbo Nadia
Published: June 2024

El desarrollo del habla, el lenguaje, la comunicación, la cognición y otros aspectos en la infancia se ven profundamente influenciados por la audición. Cuando un niño presenta pérdida auditiva no detectada o no tratada, se reducen los estímulos y se dificulta el desarrollo de habilidades lingüísticas. La falta de atención temprana puede llevar a retrasos en el desarrollo del lenguaje, afectando la capacidad del niño para comprender y comunicarse. La hipoacusia pediátrica es un problema de salud pública que afecta a un porcentaje significativo de niños en todo el mundo. El aumento de la causa de la hipoacusia infantil en diferentes países se atribuye a factores como la falta de conciencia y educación sobre la importancia de la detección temprana, la disponibilidad y acceso limitados a servicios de detección y diagnóstico, la ausencia de programas de detección temprana en algunos países y la necesidad de contar con profesionales de la salud capacitados en el manejo de la audición pediátrica. Todo ello puede afectar áreas fundamentales del desarrollo, incluyendo el lenguaje y la comunicación, el desarrollo cognitivo, sensorial, motor y adaptativo. Por tanto, este trabajo tuvo el objetivo de llevar a cabo una revisión narrativa de la literatura científica sobre la situación de las alteraciones auditivas en la población pediátrica.
Prevalencia de los tipos de cáncer que conlleva a la necesidad de oxígeno en una clínica oncológica en el periodo enero 2020 a diciembre 2021
Authors: Gómez Hernández Florangela Marcela
Published: June 2024

El cáncer genera en el organismo diferentes cambiosque afectan a la persona. El primero está dado por lainmunovigilancia tumoral y radicales libres, de igualforma la quimioterapia, radioterapia e intervencionesquirúrgicas, cada una de estas promueven elrequerimiento de oxígeno en pacientes oncológicos,desarrollando complicaciones de su enfermedady estancias hospitalarias prolongadas. Objetivo:Identificar la prevalencia de los tipos de cáncer queconllevan al uso oxígeno en una clínica en el periodo2020 a 2021. Metodología: El presente estudio es unainvestigación no experimental, descriptiva de tipomixto. Resultados: Las patologías oncológicas quemayor requirieron oxígeno en la clínica durante esteperiodo fueron colon, seguido por estómago, mamay tiroides, sin embargo, estas requieren de sistemasde bajo flujo por tiempos prolongados. Por otro lado,la leucemia uso en su mayoría de un sistema de altoflujo de oxigenación, y una proporción importanterequirió ventilación mecánica. Conclusiones:Frente al estudio se pudo identificar que el 33% delos pacientes atendidos en la clínica oncológica,requirieron oxígeno en algún momento de su estanciahospitalaria, el tipo de cáncer que requirió oxígenoen mayor prevalencia fue colon y estómago, porotro lado, el uso de este en pacientes oncológicospromueve complicaciones como aumento deradicales libres, generación de angiogénesisy apoptosis en células sanas que conllevan acomplicaciones de su enfermedad, afectando lacalidad de vida de los pacientes.
Disfunción sexual y actividad física en mujeres universitarias
Authors: Eraso Angulo Rosa Helena , Chaves Paz Claudia Ximena , Riascos Andrade Diana Lorena , Ascuntar Insuasty Hengi Cristina
Published: June 2024

Las disfunciones sexuales femeninas se describencomo un problema que afecta la salud sexual enmujeres, se ha descrito que el nivel de actividad físicapuede estar relacionado con estas disfunciones,teniendo en cuenta su influencia fisiológica, mecánicay hormonal lo que podría generar efectos en elcomponente sexual. Objetivo: determinar la relaciónentre el nivel de actividad física y la función sexualfemenina. Método: Estudio cuantitativo, descriptivo,transversal basado aplicación del instrumentodenominado índice de función sexual femenina y elcuestionario IPAQ, se realizó un análisis estadísticode tipo univariado y bivariado, el procesamientode los datos se realizó con paquete estadísticoIBM SPSS Statistics 25. Resultados: participaron134 mujeres universitarias, 52% del programa deTerapia Ocupacional y 48% de Fisioterapia, con unpromedio de edad de 22 años, el 98% de la poblaciónpertenecen a los tres niveles socioeconómicos másbajos, son solteras, sin hijos y clasifican su génerocomo heterosexual, el método de planificación másutilizado fue el implante subdérmico con un 23% y el68% refieren tener pareja sexual estable. El 31% delas participantes manifiestan que ven afectadas susrelaciones sexuales por la carga académica, mientrasque el 5% por la carga laboral. Se encontró un nivelmoderado de actividad física en un 41% y bajo en un30%. De las estudiantes 83% presentan algún tipode disfunción sexual, siendo el trastorno del deseoel más referido con un 24%, seguido del orgasmoy satisfacción global con un 21% respectivamente;con respecto a la asociación de las variables, no seencontró relación estadísticamente significativa.Conclusión: existe un alto predominio de disfuncionessexuales en las mujeres participantes, sin embargo,no se encontró asociación con el nivel de actividadfísica.
A leg model based on anatomical landmarks to study 3D joint kinematics of walking in Drosophila melanogaster
Authors: Haustein Moritz , Blanke Alexander , Bockemühl Till , Büschges Ansgar
Published: June 2024

Walking is the most common form of how animals move on land. The model organismDrosophila melanogasterhas become increasingly popular for studying how the nervous system controls behavior in general and walking in particular. Despite recent advances in tracking and modeling leg movements of walkingDrosophilain 3D, there are still gaps in knowledge about the biomechanics of leg joints due to the tiny size of fruit flies. For instance, the natural alignment of joint rotational axes was largely neglected in previous kinematic analyses. In this study, we therefore present a detailed kinematic leg model in which not only the segment lengths but also the main rotational axes of the joints were derived from anatomical landmarks, namely, the joint condyles. Our model with natural oblique joint axes is able to adapt to the 3D leg postures of straight and forward walking fruit flies with high accuracy. When we compared our model to an orthogonalized version, we observed that our model showed a smaller error as well as differences in the used range of motion (ROM), highlighting the advantages of modeling natural rotational axes alignment for the study of joint kinematics. We further found that the kinematic profiles of front, middle, and hind legs differed in the number of required degrees of freedom as well as their contributions to stepping, time courses of joint angles, and ROM. Our findings provide deeper insights into the joint kinematics of walking inDrosophila, and, additionally, will help to develop dynamical, musculoskeletal, and neuromechanical simulations.
Urban sustainability assessment: An analysis of how weighting and aggregating coefficient system was used in the development of SUCCEED assessment tool for developing countries
Authors: Momoh Job , Ige Olubisi , Seidu Rafiu , Ogbenjuwa Lucy , Young Bert , Ibraheem Yusuf
Published: June 2024

The development of a weighting and aggregating coefficient system used in urban sustainability assessment tools is a process that needs well-defined procedures using a series of steps, methodology, and a systematic approach in its development. The development of assessment tools has been successful in developed countries but developing countries would need to have a structured process that will assist in the development of an assessment tool that is tailored to its environs. This paper aims to understand the various weighting and aggregating coefficient systems employed in the development of sustainability assessment tools. Alongside using these findings to understand how these weighting and aggregating coefficients can be adopted in the development of sustainability assessment tools for developing countries based on their differences, advantages, and disadvantages. Qualitative Content Analysis based on a systematic review of existing literature was used in this study to understand various weighting and aggregating coefficients. It is imperative to note that this research will focus on how assessment tools are developed with a clear focus on sustainability assessment weighting and aggregating. The study also further analyses how a case study SUCCEED (Sustainable Composite Cities Environmental Evaluation and Design Tool) has benefited from the adoption of equal weighting and additive aggregation methods based on validation carried out. The findings of this research show that the selection of weighting and aggregating systems is defined by the relevance, importance, and purpose of the assessment tool. It also develops a guide/recommendations on the process utilised in the development of assessment tools for developing countries.
Serum C-reactive protein to albumin ratio as a potential risk indicator of pneumonia caused by Chlamydia psittaci: a multicenter retrospective study
Authors: Shi Tianyun , Yu Yunxia , Shen Yao , Shen Meili , Du Yong , Zhang Meng , Mei Zhoufang , Ding Yi , Feng Jingjing , Zhu Moran , Ge Fangxia , Zhao Qi , Wang Ruilan , Jie Zhijun
Published: June 2024

Introduction

The aim of the study was to describe psittacosis pneumonia and to assess the predictive value of the C-reactive protein/albumin ratio in psittacosis pneumonia for severity.

Methods

Data on psittacosis pneumonia cases diagnosed using metagenomic sequencing were collected from three hospitals in Shanghai, China from Oct. 2019 to Oct. 2022. Serum levels of C-reactive protein and albumin were measured and the C-reactive protein to albumin ratio (CAR) was calculated. Spearman’s correlation analysis, ordered logistic regression analysis, and receiver operating characteristic curve analysis were conducted to examine the correlation and predictive ability of the three indicators on the severity of the disease.

Results

A total of 27 patients with psittacosis pneumonia were enrolled, with an average age of 62 years and 70.4% being male. 44.4% of patients had a clear history of contact with poultry or birds. The predominant symptom was fever (100%). Patients treated in the respiratory intensive care unit (RICU) had a higher likelihood of experiencing wheezing (88.9% versus 33.3%, P=0.013) and chest tightness (88.9% vs. 33.3%, P=0.013) than those in the general ward (Non-RICU). The proportion of patients with pleural effusion was significantly higher in the RICU compared to the Non-RICU (88.9% vs. 38.9%, P=0.019). The RICU group had a significantly higher CAR than the Non-RICU group (9.41 vs. 4.05, P=0.017). This result was accompanied by higher intubation and ventilator support (33.3% vs. 0.0%, P=0.029), higher PCT and CRP levels and lower albumin and PaCO2 levels in the RICU than in the Non-RICU. Logistic regression analysis indicated that CAR (OR 1.49; 95% CI 1.07–2.06, P=0.017) was risk factor for prolonged hospitalization (> 14 days).

Discussion

Elevated serum CAR levels were found to be associated with a greater risk of severe psittacosis pneumonia. Consequently, it may serve as an uncomplicated and useful diagnostic tool for clinicians to promptly and precisely ascertain the severity of psittacosis pneumonia, ultimately aiding them in devising the most optimal therapeutic plan.
Cutting-edge research frontiers in oral cavity vaccines for respiratory diseases: a roadmap for scientific advancement
Authors: Sallard Erwan , Aydin Malik
Published: June 2024

Intramuscular vaccines present limitations in eliciting robust mucosal immunity and preventing respiratory pathogens transmission. Sublingual vaccine administration offers promising advantages, including interconnected mucosal protection. Despite these advantages, only a few clinical trials have explored sublingual vaccines, underscoring the necessity of optimizing next-generation vaccine formulas. Critical research priorities include understanding vector behavior in the oral environment, understanding their interactions with mucosal immunity and developing formulations enabling sustained mucosal contact to facilitate efficient transduction. Consequently, tonsil organoids, as representative human mucosal models, could offer critical insights into sublingual immunization. Thus, a multi-disciplinary approach integrating pharmacological, immunological, and manufacturing considerations is pivotal for sublingual vaccines in targeting pathogen-aggravated prevalent respiratory diseases including asthma, COPD and lung cancer, as well as the antimicrobial resistance crisis.
The Trypanosoma cruzi pleiotropic protein P21 orchestrates the intracellular retention and in-vivo parasitism control of virulent Y strain parasites
Authors: Silveira Anna Clara Azevedo , Uombe Nelsa Paula Inácio , Velikkakam Teresiama , Borges Bruna Cristina , Teixeira Thaise Lara , de Almeida Vitelhe Ferreira , Torres Jhoan David Aguillon , Pereira Cecília Luiza , de Souza Guilherme , Teixeira Samuel Cota , Servato João Paulo Silva , Silva Marcelo José Barbosa , Mineo Tiago Wilson Patriarca , Ribas Rosineide Marques , Mortara Renato Arruda , da Silveira José Franco , da Silva Claudio Vieira
Published: June 2024

P21 is a protein secreted by all forms of Trypanosoma cruzi (T. cruzi) with recognized biological activities determined in studies using the recombinant form of the protein. In our recent study, we found that the ablation of P21 gene decreased Y strain axenic epimastigotes multiplication and increased intracellular replication of amastigotes in HeLa cells infected with metacyclic trypomastigotes. In the present study, we investigated the effect of P21 in vitro using C2C12 cell lines infected with tissue culture-derived trypomastigotes (TCT) of wild-type and P21 knockout (TcP21−/−) Y strain, and in vivo using an experimental model of T. cruzi infection in BALB/c mice. Our in-vitro results showed a significant decrease in the host cell invasion rate by TcP21−/− parasites as measured by Giemsa staining and cell count in bright light microscope. Quantitative polymerase chain reaction (qPCR) analysis showed that TcP21−/− parasites multiplied intracellularly to a higher extent than the scrambled parasites at 72h post-infection. In addition, we observed a higher egress of TcP21−/− trypomastigotes from C2C12 cells at 144h and 168h post-infection. Mice infected with Y strain TcP21−/− trypomastigotes displayed higher systemic parasitemia, heart tissue parasite burden, and several histopathological alterations in heart tissues compared to control animals infected with scrambled parasites. Therewith, we propose that P21 is important in the host–pathogen interaction during invasion, cell multiplication, and egress, and may be part of the mechanism that controls parasitism and promotes chronic infection without patent systemic parasitemia.
Assessment of performance and comparison of three commercial HDV RNA detection assays: implications for diagnosis and treatment monitoring
Authors: Illescas-López Marta , Chaves-Blanco Lucía , de Salazar Adolfo , Hernández-Febles Melisa , Carracedo Raquel , Lagarejos Eduardo , Fuentes Ana , Pereira Sara , Cea Maria , De La Iglesia Alberto , Freyre Carolina , Iborra Asunción , Odero Valle , García-Barrionuevo Aurora , Aguilera Antonio , Pena María José , García Federico
Published: June 2024

Objectives

Precise HDV-RNA detection and quantification are pivotal for diagnosis and monitoring of response to newly approved treatment. We evaluate the performance of three HDV RNA detection and quantification assays.

Methods

Hepatitis Delta RT-PCR system kit, EurobioPlex HDV assay, and RoboGene HDV RNA Quantification kit 2.0 were used for testing 151 HBsAg-positive samples, 90 HDV-RNA negative and 61 HDV-RNA positive. We also evaluated serial dilutions of the WHO international standard for HDV, PEI 7657/12. All HDV-RNA positive samples were genotyped using a next-generation sequencing strategy.

Results

Qualitative results indicated a 100% concordance between tests. Quantitative results correlated well, r2 = 0.703 (Vircell-vs-Eurobio), r2 = 0.833 (Vircell-vs-RoboGene), r2 = 0.835 (Robogene-vs-Eurobio). Bias index was 2.083 (Vircell-vs-Eurobio), -1.283 (Vircell-vs-RoboGene), and -3.36 (Robogene-vs-Eurobio). Using the WHO IS, Vircell overestimated the viral load by 0.98 log IU/mL, Eurobio by 1.46 log IU/mL, and RoboGene underestimated it by 0.98 log IU/mL. Fifty-nine samples were successfully genotyped (Genotype 1, n=52; Genotype 5, n=7; Genotype 6, n=1), with similar results for correlation and bias.

Conclusion

This study underscores the necessity of using reliable HDV-RNA detection and quantification assays, as evidenced by the high concordance rates in qualitative detection and the observed variability in quantitative results. These findings highlight the importance of consistent assay use in clinical practice to ensure accurate diagnosis and effective treatment monitoring of HDV infection.
Pre-contact Indigenous fire stewardship: a research framework and application to a Pacific Northwest temperate rainforest
Authors: Coughlan Michael R. , Johnston James D. , Derr Kelly M. , Lewis David G. , Johnson Bart R.
Published: June 2024

Fire is a key disturbance process that shapes the structure and function of montane temperate rainforest in the Pacific Northwest (PNW). Recent research is revealing more frequent historical fire activity in the western central Cascades than expected by conventional theory. Indigenous peoples have lived in the PNW for millennia. However, Indigenous people's roles in shaping vegetation mosaics in montane temperate forests of the PNW has been overlooked, despite archaeological evidence of long-term, continuous human use of these landscapes. In this paper, we present a generalizable research framework for overcoming biases often inherent in historical fire research. The framework centers Indigenous perspectives and ethnohistory, leveraging theory in human ecology and archaeology to interpret fire histories. We apply this framework to place-based, empirical evidence of Indigenous land use and dendroecological fire history. Our framework leads us to conclude that the most parsimonious explanation for the occurrence of historical high fire frequency in the western Cascades is Indigenous fire stewardship. Further, our case study makes apparent that scholars can no longer ignore the role of Indigenous people in driving montane forest dynamics in the PNW.
Hypertonicity during a rapid rise in D-glucose mediates first-phase insulin secretion
Authors: Kamat Varun , Sweet Ian R.
Published: June 2024

Introduction

Biphasic insulin secretion is an intrinsic characteristic of the pancreatic islet and has clinical relevance due to the loss of first-phase in patients with Type 2 diabetes. As it has long been shown that first-phase insulin secretion only occurs in response to rapid changes in glucose, we tested the hypothesis that islet response to an increase in glucose is a combination of metabolism plus an osmotic effect where hypertonicity is driving first-phase insulin secretion.

Methods

Experiments were performed using perifusion analysis of rat, mouse, and human islets. Insulin secretion rate (ISR) and other parameters associated with its regulation were measured in response to combinations of D-glucose and membrane-impermeable carbohydrates (L-glucose or mannitol) designed to dissect the effect of hypertonicity from that of glucose metabolism.

Results

Remarkably, the appearance of first-phase responses was wholly dependent on changes in tonicity: no first-phase in NAD(P)H, cytosolic calcium, cAMP secretion rate (cAMP SR), or ISR was observed when increased D-glucose concentration was counterbalanced by decreases in membrane-impermeable carbohydrates. When D-glucose was greater than 8 mM, rapid increases in L-glucose without any change in D-glucose resulted in first-phase responses in all measured parameters that were kinetically similar to D-glucose. First-phase ISR was completely abolished by H89 (a non-specific inhibitor of protein kinases) without affecting first-phase calcium response. Defining first-phase ISR as the difference between glucose-stimulated ISR with and without a change in hypertonicity, the peak of first-phase ISR occurred after second-phase ISR had reached steady state, consistent with the well-established glucose-dependency of mechanisms that potentiate glucose-stimulated ISR.

Discussion

The data collected in this study suggests a new model of glucose-stimulated biphasic ISR where first-phase ISR derives from (and after) a transitory amplification of second-phase ISR and driven by hypertonicity-induced rise in H89-inhibitable kinases likely driven by first-phase responses in cAMP, calcium, or a combination of both.