bluuebunny/crossref_metadata_2025 huggingface dataset:
Post-cheilorhinoplasty esthetic evaluation of unilateral cleft lip and palate infants treated with and without pre-surgical nasoalveolar molding
Authors: Bhusri Navdeep , Lim Dennis C. , Pandan Maria Janet Mapa
Published: November 2023

Objectives:

Unilateral cleft lip and palate sets many challenges both functional and esthetic. Cleft patients are at an elevated risk for developing psychosocial problems. The objective of this study was to assess any difference in esthetics post-cheilorhinoplasty in unilateral cleft lip and palate (UCLP) infants treated with and without nasoalveolar molding.

Materials and Methods:

Esthetic evaluation of nasolabial appearance and comparative analysis of photographic records collected post-cheilorhinoplasty for presurgical nasoalveolar molding (PNAM), lip-tape (LPTP), no pre-treatment (NoPreTx), and control (CTRL) groups were done using 5 point scale. There were six evaluators, two orthodontists, and one maxillofacial surgeon each from the two participating institutions. Paired “t”-test for nasolabial score comparison between groups, Cronbach’s alpha for reliability analysis, and Fleiss Kappa for interevaluator agreement were used for statistics. All statistical analysis was done at confidence level of 95% and 0.05 as level of significance.

Results:

Significant difference was found between nasolabial esthetic scores for PNAM group when compared to LPTP (P = 0.000) and NoPreTx (P = 0.001) groups. Infants who underwent PNAM had better nasolabial esthetic scores in all categories compared to infants who underwent LPTP or NoPreTx. The scale of measurement and the nasolabial esthetic evaluation scores were coherent and reliable as shown by Crohnbach’s alpha (<0.9) both for individual components and for overall score.

Conclusion:

UCLP infants who were brought by their parents to the craniofacial center early within 1 month of their birth and who underwent nasoalveolar molding therapy before cheilorhinoplasty had significantly better nasolabial esthetics post-surgery.
Use of the temporalis muscle flap in reconstructive surgery of extensive eyelid defects
Authors:   The S. Fyodorov Eye Microsurgery Federal State Institution, the Khabarovsk Branch, Khabarovsk, Russian Federation, Kolenko O.V. ,   Far-Eastern State Medical University, Khabarovsk, Russian Federation,   Postgraduate Institute for Public Health Workers, Khabarovsk, Russian Federation, Banshchikov P.A. ,   The S. Fyodorov Eye Microsurgery Federal State Institution, the Khabarovsk Branch, Khabarovsk, Russian Federation
Published: November 2023

Монография посвящена новому методу хирургического лечения обширных рубцовых дефектов век. Это одноэтапная реконструкция с использованием трехсоставного лоскута, в состав которого входит лоскут височной мышцы. В ней подробно изложена хирургическая техника выполнения метода у пациентов с обширными рубцовыми дефектами век. Описан метод математического прогнозирования ожидаемого результата по характеру завершения репаративного процесса при различных вариантах одноэтапной сложносоставной пластики рубцовых дефектов век.
Water-soluble and Water-dispersible Polymers Used in Commercial Agricultural Formulations: Inventory of Polymers and Perspective on their Environmental Fate
Authors: Kleemann Kevin , Sander Michael
Published: November 2023

Agricultural formulations contain water-soluble and water-dispersible polymers (WSPs and WDPs) to increase the application efficiency of the active ingredients (e.g. pesticides and fertilizers). Despite their direct release to soils and crops, there is currently no inventory of used polymers and their fate in soils is poorly studied and understood. Herein, we identify WSPs and WDPs used in agricultural formulations on the German and Swiss markets. By searching the scientific literature, patents, and manufacturer websites, we tentatively identified that 233 of the 1815 listed trade names of formulation additives contained polymers, the majority of which belonged to three main chemical classes: polyethylene glycol (PEG)-based (co)polymers, functionalized polysaccharides (PSacs), and vinylic (co)polymers (VCPs). We report information on their functionalization, molecular weights, and market significance. In 2015, their estimated combined annual application volume in Switzerland surpassed 100 tonnes. Low molecular weight PEGs and natural, unfunctionalized PSacs reportedly biodegrade, suggesting no accumulation in soils associated with their use as formulation additives. Conversely, high molecular weight functionalized PEGs, functionalized PSacs, and the majority of the VCPs have been reported to undergo only slow or no soil biodegradation. These polymers may thus persist and accumulate in agricultural soils, requiring more detailed investigations of their environmental fate and resulting exposure scenarios. There is a need for systematic studies on the effects of polymer structure, molecular weight, and functionalization on soil biodegradability.
Anthelminthic Veterinary Medicines Interactions with the Soil Microbiota
Authors: Lagos Stathis , Karpouzas Dimitrios G.
Published: November 2023

Anthelminthics (AHs) are used to control gastrointestinal nematodes (GINs) in productive animals. They are rapidly excreted by animals, ending up in soil through direct deposition of animal dung or application of animal excreta as manures. Most environmental research on AHs has focused on their toxicity to aquatic organisms and soil fauna while their interactions with the soil microbiota, a key component of a functioning soil ecosystem, have been overlooked. In this article, we summarize current knowledge on the interactions of Ahs with the soil (micro) biota, we highlight recent evidence for the toxicity of AHs on soil microorganisms and discuss those results in the frame of the current environmental risk assessment (ERA) of veterinary medicines.
Impact of treatment with sling placement for stress urinary incontinence on quality of life: case report and literature review
Authors: Andrade Marcos Alécio Bispo de , Almeida José Carlos de , Vieira Marcelo , Santos Eduesley Santana
Published: November 2023

Introduction: urinary incontinence is defined as a condition of involuntary leakage of urine. Although minimal, incontinence is associated with a significant decline in quality of life, social, professional, and mental health, as well as sexual dysfunction in these women. Objective: To report the impact of sling used on the long-term quality of life of a patient with stress urinary incontinence. Case Report: 37-year-old patient without comorbidities, five pregnancies, three natural deliveries, one cesarean section, and one abortion, with an interval between deliveries of approximately one year. She began to experience mild urinary incontinence at medium and heavy exertion (cycling, climbing stairs quickly, carrying weight) or in near-maximum bladder capacity, in drips, with progressive worsening of symptoms over time that negatively impacted her quality of life. After several outpatient evaluations and with the persistence of symptoms, the patient underwent insertion of a mid-urethral sling. Conclusion: the use of a urethral sling had a positive impact on the control of incontinence and improvement in the long-term quality of life of a young patient with stress urinary incontinence.
Variações de peso no primeiro ano de graduação em universitários na área da saúde / Variations in weight in the first year of undergraduate studies in health
Authors: Cardoso Luciana Gonzaga dos Santos , Coyado Mariá Spina , Ávila Lívia Keismanas de
Published: November 2023

Introdução: O ingresso à universidade pode alterar significativamente o estilo de vida dos estudantes para melhor ou pior devido a novas atividades e rotina, o que favorece a variações de peso entre eles. Objetivo: Identificar as variações de peso e sua relação com o Estilo de Vida em universitários da área da saúde, durante o primeiro ano de graduação. Material e Método: Pesquisa de campo, prospectiva, longitudinal e de análise quantitativa dos dados com 123 universitários de uma instituição de ensino na área da saúde. Resultados: A variação de peso ao final doprimeiro semestre foi de -6,3 a 20,5 kg, com mediana de 0,7 kg. No segundo semestre variou de -17,0 a 5,1 kg, com mediana de 0,3 kg. A variação da pontuação do Estilo de Vida Fantástico ao final do primeiro semestre foi de -36 a 16, com mediana de -5 pontos. No segundo semestre, a variação foi de -24 a 18, com mediana de 0 pontos. Conclusão: O ganho de peso foi maior que a perda nos dois semestres. No primeiro semestre, a piora no estilo de vida predominou nos que ganharam e nos que perderam peso. No segundo semestre, observou-se que a piora no estilo de vida foi maior entre os que ganharam peso, porém, entre os que perderam peso, predominaram estudantes que melhoraram o estilo de vida.Palavras-chave: Estudantes de Ciências da Saúde, Perda de peso, Ganho de peso, Estilo de vida.
ABSTRACT:
Introduction: Admission to university can significantly alter students’ lifestyle for better or worse due to new activities and routine, which favors weight variations among them. Objective: To identify the variations of weight and their relation with the lifestyle of university students of the health area, during the first year of graduation. Method: Field research, with a prospective, longitudinal and quantitative data analysis of 123 university students from a health education institution. Results: The weight variation at the end of the first semester was -6.3 to 20.5 kg, with a median of 0.7 kg. In the second semester it varied from -17.0 to 5.1 kg, with a median of 0.3 kg. The variation of the Fantastic Lifestyle score at the end of the first semester was -36 to 16, with a median of -5 points. In the second semester the variation was -24 to 18, with a median of zero points. Conclusion: Weight gain was greater than the loss in the two semesters. In the first semester, the worsening in lifestyle predominated in those who gained and those who lost weight. In the second semester, it was observed that the worsening of the lifestyle was greater among those who gained weight; however, among those who lost weight, students who improved their lifestyle predominated.Keywords: Students, Health Occupations; Weight loss; Weight gain; Life style.
Direct Control of Electron Spin at Chiral Active Sites for Highly Efficient Oxygen Reduction Reaction
Authors: Wang Xia , Peralta Mayra , Li Xiaodong , Möllers Paul V. , Zhou Dong , Merz Patrick , Burkhardt Ulrich , Borrmann Horst , Iñigo Robredo Magro , Chandra Shekhar , Zacharias Helmut , Feng Xinliang , Felser Claudia
Published: November 2023

The oxygen reduction reaction (ORR) in acidic suffers from sluggish kinetics owing to the spin-dependent electron transfer process. However, the direct generation of spin-polarized electron at catalytic active sites remains elusive and the underlying mechanism is still controversial due to the lack of intrinsically homochiral catalysts. To address this challenge, we demonstrate the topological homochiral PdGa (TH PdGa) crystal with chiral active sites for ORR. Spin-resolved photoemission and theoretical simulations probed the in-situ generated spin polarizations at Pd sites. Both structural chirality and spin-orbital coupling are essential for inducing spin polarization. TH PdGa with remarkable concentration of spin-polarized electron outperforms the benchmark Pt/C by about 70 times in terms of kinetic current density at 0.85 V vs. the reversible hydrogen electrode (RHE) and over 200 times in terms of the turnover frequency. This work allows us to elucidate the respective contributions of spin polarization to the enhanced acidic ORR activity.
Probing Ion-Receptor Interactions in Halide Complexes of Octamethyl Calix[4]Pyrrole
Authors: Terry Lane M. , Foreman Madison M , Rasmussen Anne P , McCoy Anne B , WEBER J. Mathias
Published: November 2023

The interplay of solvation and ion binding in anion host-guest complexes in solution governs the binding efficiency and selectivity of ion receptors. To gain molecular-level insight into the intrinsic binding properties of octamethyl calix[4]pyrrole (omC4P) host molecules with halide guest ions, we performed cryogenic ion vibrational spectroscopy (CIVS) of omC4P in complexes with fluoride, chloride, and bromide ions. We interpret the spectra using density functional theory, describing the infrared spectra of these complexes with both harmonic and anharmonic VPT2 calculations. The NH stretching modes of the pyrrole moieties serve as sensitive probes of the ion binding properties, as their frequencies encode the ion-receptor interactions. While scaled harmonic spectra reproduce the experimental NH stretching modes of the chloride and bromide complexes in broad strokes, the high proton affinity of fluoride introduces strong anharmonic effects. As a result, the spectrum of F−·omC4P is not even qualitatively captured by harmonic calculations, but it is recovered very well by VPT2 calculations. In addition, the VPT2 calculations recover the intricate coupling of the NH stretching modes with overtones and combination bands of CH stretching and NH bending modes and with low-frequency vibrations of the omC4P macrocycle, which are apparent for all halide ion complexes investigated here. A comparison of the CIVS spectra with infrared spectra of solutions of the same ion-receptor complexes shows how ion solvation changes the ion-receptor interactions for the different halide ions.
Structure-activity studies of 1,2,4-oxadiazoles for the inhibition of the NAD+ dependent lysine deacylase Sirtuin2
Authors: Colcerasa Arianna , Friedrich Florian , Melesina Jelena , Moser Patrick , Vogelmann Anja , Tzortzoglou Pavlos , Neuwirt Emilia , Sum Manuela , Zhang Lin , Ramos-Morales Elizabeth , Romier Christophe , Einsle Oliver , Metzger Eric , Schüle Roland , Gross Olaf , Sippl Wolfgang , Jung Manfred
Published: November 2023

The NAD+-dependent lysine deacylase Sirtuin2 (Sirt2) is involved in multiple pathological conditions, including cancer and targeting Sirt2 has thus received an increased interest for therapeutic purpose. Furthermore, addressing the ortholog from Schistosoma mansoni (SmSirt2) has been considered for the potential treatment of the neglected tropical disease schistosomiasis. We previously identified a 1,2,4-oxadiazole-based scaffold from the screening of the “Kinetobox” library as a dual inhibitor of human Sirt2 and SmSirt2. Herein, we describe structure-activity studies on 1,2,4-oxadiazole based analogs, which are potent inhibitors of human Sirt2 deacetylation. As proposed by docking studies, a substrate competitive and co-factor non-competitive binding mode of inhibition could be determined in vitro via binding assays and kinetic analysis, and further confirmed by a crystal structure of an oxadiazole inhibitor in complex with hSirt2. Optimized analogs reduced cell viability and inhibited prostate cancer cell migration, in correlation with Sirt2 deacetylase inhibition both in vitro and in cells.
A high macro molecular ghost in SEC analysis of conjugate polymer
Authors: Yamaoka Seiha , Okano Kentaro , Mori Atsunori
Published: November 2023

SEC (size exclusion chromatography) analyses of conjugated polymers (polythiophene and polyphenylene) were carried out. When a semimicro analytical column was employed for the measurement of the molecular weight, an extremely large molecular weight peak (>100000 Da) was observed. Preparative SEC of each fraction and the further analysis revealed that such a high-molecular-weight peak was only found in the analysis with a semimicro column and found that the ghost peak was derived from low-molecular-weight fraction (M < 4000), which would form aggregation to higher molecular weight of earlier eluate in SEC.
Speciation and organic phase structure in nitric acid extraction with trioctylamine
Authors: Nayak Srikanth , Servis Michael J. , Combs Derrick , Szeliga Krystian , Seifert Soenke
Published: November 2023

Understanding chemical speciation and intermolecular interactions in multicomponent liquids is essential to understanding their phase behavior, which underpins chemical separation processes including solvent extraction. Here we report on the extraction of nitric acid from its aqueous solutions into organic solutions of trioctylamine (TOA) in toluene, investigated with spectroscopic, X-ray scattering, and computational tools to understand the molecular speciation in the organic phase and its relationship with the nanoscale structure of the organic phase. Trends in acid and water extraction clearly show two and three regimes, respectively, but the speciation of HNO3, water, and amine in these regimes is not apparent. 1H-NMR of the organic phase shows that there are at least two distinct acidic protons in the organic phase while ATR-FTIR results show that the organic phase with excess acid extraction is a mixture of trioctylammonium-nitrate ion pairs (TOAH.NO3), and undissociated HNO3 molecules. Comparison with DFT-computed IR spectra show that the chain-like configurations of TOAH.NO3.HNO3.H2O are favored over TOAH.NO3.H2O.HNO3, i.e., direct interaction between the two HNO3 molecules is more favored compared to a water-mediated interaction. SAXS of the organic phases were modeled as sums of Ornstein-Zernike (O-Z) scattering and a prepeak feature in the higher Q region, corresponding to features from density fluctuations and extractant packing, respectively. The extraction of undissociated HNO3 by the ion pairs leads to an increased X-ray scattering contrast in the organic phase without any significant change in the O-Z correlation length. These results show that the organic phase nanostructure is more sensitive to the concentration of TOAH.NO3 and is relatively unaffected by excess acid extraction. These findings will enable a molecular understanding of the mechanisms behind metal extractions from acidic media with basic extractants.
Synthetic Protein-to-DNA Input Exchange for Protease Activity Detection Using CRISPR-Cas12a
Authors: Capelli Luca , Pedrini Federica , Di Pede Andrea C. , Bagheri Neda , Fortunati Simone , Giannetto Marco , Mattarozzi Monica , Corradini Roberto , Porchetta Alessandro , Bertucci Alessandro
Published: November 2023

We present a novel activity-based detection strategy for matrix metalloproteinase 2 (MMP2), a critical cancer protease biomarker, leveraging a mechanism responsive to the proteolytic activity of MMP2 and its integration with CRISPR-Cas12a-assisted signal amplification. We designed a chemical translator comprising two functional units — a peptide and a peptide nucleic acid (PNA) — fused together. The peptide presents the substrate of MMP2, while the PNA serves as a nucleic acid output for subsequent processing. This chemical translator was immobilized on micrometric magnetic beads as a physical support for an activity-based assay. We incorporated into our design a single-stranded DNA partially hybridized with the PNA sequence and bearing a region complementary to the RNA guide of CRISPR-Cas12a. The target-induced nuclease activity of Cas12a results in the degradation of FRET-labeled DNA reporters and amplified fluorescence signal, enabling detection of MMP2 in the low picomolar range, showing a limit of detection of 72 pg/mL. This study provides new design principles for a broader applicability of CRISPR-Cas-based biosensing.
Following structural changes in iridium nanoparticles during oxygen evolution electrocatalysis with operando X-ray total scattering
Authors: Pittkowski Rebecca , Punke Stefanie , Anker Andy S. , Bornet Aline , Magnard Nicolas , Schlegel Nicolas , Mirolo Marta , Drnec Jakub , Kirkensgaard Jacob J. K. , Arenz Matthias , Jensen Kirsten M. Ø.
Published: November 2023

Understanding the structure of nanoparticles under (electro)catalytic operating conditions is crucial for uncovering structure-property relationships. By combining operando X-ray total scattering and PDF analysis with operando small angle X-ray scattering, we obtain comprehensive structural information on ultra-small (< 3 nm) iridium nanoparticles and track their changes during the acidic oxygen evolution reaction. When subjected to electrochemical conditions at reducing potentials, the metallic Ir nanoparticles are found to be decahedral clusters. Upon electrochemical oxidation, iridium oxide forms, containing small rutile-like clusters composed of edge- and corner-connected [IrO6] octahedra of very confined range. These rutile domains are less than 1 nm. Combined with SAXS analysis of the particle size, we find that the iridium oxide phase active in the oxygen evolution reaction (OER) lacks crystalline order.
Advance Care Directives: A Herzl Clinic Quality Improvement Project on Patients' perspectives
Authors: Hersson-Edery Fanny
Published: November 2023

Background: Advance Care Planning (ACP) has benefits for patients and is often optimal when done in the primary care setting. Despite the development of multiple resources and tools to support ACP discussions at our Family Medicine Teaching Clinic, the initiation and documentation of Advance Care Directives (ACD) in patients’ medical files were low and resident physicians had perceived that patients were unwilling or unprepared for ACP discussions. The goal of this project was to understand the challenges and barriers that patients and their caregivers face in initiating and discussing ACD with their primary care team.

Methods:

An online survey was conducted among 78 patients who are part of the Home Care program at the Herzl clinic. Participants were asked about the value placed on ACP and their preferences on various aspects surrounding the initiation of ACD discussions.

Results:

25 of 78 possible responses were received. This included survey responses from 6 patients, 13 caregivers, 4 family members and 2 physicians. Our results show that patients and their caregivers value Advance Care Planning discussions (>80%). Additionally, they endorse multiple benefits of ACP for themselves, their care teams and families. Patients and caregivers prefer that medical professionals initiate and facilitate the discussions (70-80%) and are open to receive educational material to prepare for these discussions (68%).

Conclusion: Patients in a frail population are willing and open to discuss advance care planning with their primary care team. Family Medicine teaching clinics can support patients’ desire to engage in ACP by providing access to education material and initiating these discussions.
Neurobiogical and biochemical mechanisms of the influence of alcohol on the central nervous system and cognitive personal activity
Authors: Vovk Viktoriya , Strashok Oleg
Published: November 2023

Topicality. The problem of alcohol addiction remains an acute medical and social problem. The intense stressful biochemical background of today greatly burdens alcohol abuse with all the consequences that follow. Given the availability of alcohol in our country, the negative multi-organ effects, including on the nervous and mental systems and cognitive functions, as well as the attractiveness of its rapid anxiolytic, hypnotic and other effects, the problem of alcohol addiction requires close attention of specialists.

The purpose of this work was to determine the neurobiological and biochemical mechanisms of the formation of cognitive disorders due to alcohol consumption.

Materials and methods: Modern scientific publications on neurobiological and biochemical mechanisms of the effect of ethanol on the central nervous system and, as a result, on human cognitive activity were analyzed.

Results: The analysis of literature data showed that with alcohol addiction, the frontal lobes of the cerebral hemispheres are more prone to damage, which is manifested by a violation of executive functions (ability to abstract and plan, inhibition of perseverative processes, switching between different cognitive processes, speed of cognitive processes, etc.). The neurotransmitter systems of the brain are also negatively affected. The disease progresses as the compensatory capabilities of the body are exhausted, the role of which is performed by the increased synthesis of catecholamines in the central nervous system. Hypotheses explaining the phenomenology of the neuropsychological defect in alcoholism are considered.

Conclusions: Thus, timely detection of brain dysfunctions associated with alcohol dependence in patients is of great importance at all stages of work - both in diagnostic and therapeutic processes. Also, theses from the given analytical data can be used when conducting psychoeducation as a stage of CBT intervention in alcohol addiction for all participants of the therapeutic process.
Stroke prevention as a psychological problem
Authors: Bondarenko Nikita
Published: November 2023

The article presents an overview of research into psychological factors of stroke. It was determined that the susceptibility to stroke is formed by the following psychological qualities: high emotionality, anxiety, intrapersonal conflict, tension, reduced stress resistance, difficulties in social and psychological adaptation. Two personality psychotypes (A and B )were noted, to which increased risk for stroke is attributed:1) extroverts, with a fast pace of reactions and emotional excitability, competitiveness, desire for achievements, conflict and a constant feeling of time pressure, impulsive, egocentric, situationally anxious; 2) introverts, emotionally unbalanced, with a changeable character and a tendency to low mood, anxious and prone to depression, insecure. Based on data analysis, it is emphasized the need to learn effective methods of overcoming stress and reducing anxiety, increasing the level of communicative competence and learning effective methods of overcoming conflicts, mastering methods of emotional self-regulation for stroke prevention. Psychological recommendations are proposed for implementation in the lifestyle of the general public for the prevention of psychosomatic diseases.
ENGENHARIA DIDÁTICA COMO METODOLOGIA DE PESQUISA NOS TRABALHOS PUBLICADOS NO EBRAPEM (2014-2021)
Authors: Miranda Natali de Jesus Ferreira de , Santos Maria de Lourdes Silva , Sá Pedro Franco de
Published: November 2023

O termo Engenharia Didática foi definido por Michèlle Artigue (1996) e caracterizado como procedimentos metodológicos que se assemelham ao trabalho do engenheiro ao realizar um projeto arquitetônico, ou seja, trata-se da concepção, planejamento e execução de um projeto. A partir da divulgação das ideias de Artigue a Engenharia Didática (ED) vem sendo utilizada como metodologia de pesquisa por educadores de diversas áreas. Considerando tal temática, nos sentimos motivados a investigar a seguinte questão problema: Quais pesquisas apresentadas no Encontro Brasileiro de Estudantes de Pós-Graduação em Educação Matemática (EBRAPEM), no período de 2014 a 2021, fazem utilização da Engenharia Didática como metodologia? Diante disso, o presente artigo tem por objetivo analisar a presença da ED como metodologia de pesquisa em trabalhos apresentados no EBRAPEM de 2014 a 2021. Para a elaboração desse artigo foi realizada pesquisa bibliográfica nos anais do evento nesse período e uma ampliação do estudo de Lopes; Palma e Sá (2018) que tinha analisado trabalhos de 2014 a 2016. O resultado alcançado indicou a presença constante da ED nas edições do evento, assim como, uma queda do percentual de trabalhos com utilização da Engenharia Didática como metodologia a partir de 2017. Concluímos que a ED é uma metodologia importante e eficiente para se investigar o processo de ensino aprendizagem de matemática e útil para desenvolver novos modos de ensino.
UM OLHAR SOBRE A PSICOLOGIA DA APRENDIZAGEM EM MATEMÁTICA NO CONTEXTO DE TEORIAS COGNITIVAS DO PENSAMENTO MATEMÁTICO AVANÇADO
Authors: Messias Maria Alice de Vasconcelos Feio , Brandemberg João Cláudio
Published: November 2023

Apresenta-se neste artigo uma discussão relacionada a Psicologia da Aprendizagem em Matemática, tendo em vista os apontamentos de Skemp (1987), no contexto do Pensamento Matemático Avançado. Para tanto, apresentou-se uma reflexão sobre a noção de Esquema e suas implicações na aprendizagem matemática, sobretudo, no que se refere às múltiplas associações entre conceitos, representações, interpretações, dentre outros elementos, os quais são parte constituinte do processo de construção do conhecimento matemático, fato que tem sido discutido no âmbito dos estudos associados ao Pensamento Matemático Avançado. Por isso, destacam-se alguns apontamentos relacionados à sua natureza, tendo em vista os trabalhos de Tall (1991,1992), Dreyfus (1991), Ervinck (1991) e Messias (2018), bem como às teorias sobre Imagem Conceitual e Definição Conceitual (VINNER, 1991) e APOS (DUBINSKY et al., 1988; ARNON et al, 2014).  Evidenciou-se a relevância dessas perspectivas teóricas, uma vez que elas permitem visualizar o processo de apreensão de conhecimentos por parte dos estudantes mediante uma pluralidade de construções mentais, por meio das quais é possível conjecturar sobre conflitos cognitivos, bem como sobre os mecanismos e processos mentais necessários para superá-los e, consequentemente, viabilizar uma compreensão mais madura dos objetos matemáticos em estudo, tornando-os significativos à realidade e necessidades dos educandos.
Excessive Use of the Preferred Foot in on-The-Ball Skills Execution Compromises Performance and Tactical Behaviour of Football Players
Authors: Mattos dos Reis Marcos Antônio , Hallé Petiot Grégory , Bezerra Almeida Marcos
Published: November 2023

This study aimed to compare tactical behaviour and performance of football players with different on-the-ball skills execution functional technical asymmetry levels and to verify whether functional technical and tactical performance indexes of football players are associated. The sample included 59 football players (14.2 ± 1.5 years of age). FUT-SAT and SAFALL-FOOT were used as instruments for performance analysis. Participants were divided in two groups: higher and lower functional technical asymmetry. Student’s t-test was used to compare the behaviour and tactical performance of the groups, and the Pearson test was used to verify associations between functional technical asymmetry and tactical performance indexes. A significance level of 5% was adopted. The higher functional technical asymmetry group showed less tactical efficiency (t57 = 1.9; p = .05; d = .17) and low performance results in the execution of defensive actions (t57 = 2.1; p = .04; d = .55; t57 = 2.1; p = .04; d = .61) compared to the lower functional technical asymmetry group. No association was found between the functional technical asymmetry and tactical performance indexes (r = -.06; p = .66). It is concluded that the levels of functional technical asymmetry affected the behaviour and tactical performance of players although functional technical asymmetry and tactical performance indexes values are not associated. Future investigations may verify how football players with high and low levels of functional technical asymmetry change their behaviour and tactical performance from different kinds of training.
Effects of plyometric jump training on running economy in endurance runners
Authors: Dudagoitia Barrio Ekaitz , Fernández-Landa Julen , Negra Yassine , Ramirez-Campillo Rodrigo , García de Alcaraz Antonio
Published: November 2023

Running economy (RE) has a strong relationship with distance running performance and is defined as the energy demand for a given velocity. Plyometric jump training may improve RE. The present study aimed to assess the effects of plyometric jump training on endurance runners’ running economy and to estimate the effectiveness of program duration, training frequency, total sessions, age, training status and velocity. A literature search was performed using PubMed/MEDLINE, Web of Science, and SCOPUS databases. Subgroup and single training factor analyses of program duration, frequency, total sessions, chronological age, training status, and running velocity were performed. A random-effects model for meta-analyses was used. Eighteen studies were selected for the systematic review and 10 for the meta-analysis. A trivial effect was noted for plyometric jump training on running economy (ES=0.19). However, plyometric jump training combined with resistance training revealed a large effect on running economy (ES=1.34). Greater running economy improvements were noted after training interventions with >15 total sessions (ES=1.00), >7 weeks (ES=0.95) and >2 days/week (ES=0.89). The youngest (ES=0.95) and highly trained participants (ES=0.94) with faster velocities (ES=0.95) obtained better results. Our findings highlight the effect of plyometric jump training that may improve running economy, particularly in combination with resistance training, after longer-term interventions (i.e., >15 total sessions, >7 weeks), with greater frequency, and among younger and more highly trained runners, especially during running at higher competitive velocities.
An approach to harmonic optimization for 25KVA auxiliary converter used in indian railway
Authors: Shawanti Roy , Sayan Paramanik , Krishna Sarker
Published: November 2023

As the Indian railway network expands, the demand for reliable and efficient power systems, especially auxiliary converters supporting various on-board systems, grows. By reducing power losses and fuel consumption, it is more crucial to design an energy-efficient and economic auxiliary converter for the railway system. This is partially accomplished by using a 25KVA auxiliary (Aux.) converter, which can accept input electrical energy from a 110V DC battery at Self-Generation (SG) coaches. Biogeography Based Optimization (BBO) method of harmonic elimination for a 25KVA converter is described in this study. The paper explores the 120-degree mode of conduction and compares the existing technique with a proposed 7-switching selective odd harmonic removal method. Results from Matlab simulations demonstrate the effectiveness of the BBO technique in reducing Total Harmonic Distortion (THD). The output voltage waveforms with and without BBO are compared, showcasing a significant improvement in harmonic suppression. The paper concludes by emphasizing the practical implementation of the optimized switching angles using an ATmega2560R3 microcontroller. The online application of stored switching angles on the microcontroller is calculated offline.
As percepções e limitações acerca do conceito de sustentabilidade: um estudo com agricultores familiares
Authors: Traça Rebeca Ribeiro , Godoy Cristiane Maria Tonetto , Campos José Ricardo da Rocha , Oliveira Paulo Henrique de
Published: November 2023

Para alcançarmos a proposta de desenvolvimento sustentável é necessário que a sociedade considere a reformulação dos valores e percepções de forma a orientar as práticas ambientais, sociais e econômicas. Nessa busca por novos valores, também se torna imperativo a inclusão social participativa dos indivíduos, gerando discussões e reflexões acerca da construção da sustentabilidade. Nesse sentido, o presente trabalho teve como objetivo compreender qual a percepção dos agricultores familiares do município de Vitorino Paraná, sobre o conceito de sustentabilidade e práticas produtivas sustentáveis, contrapondo as práticas convencionais. Para alcançar o objetivo proposto foram realizadas entrevistas com os agricultores familiares do município. Como resultados, foi observado que a temática sobre a sustentabilidade não é de domínio dos agricultores familiares, pois muitos desconhecem o significado e a existência de práticas mais ecologicamente corretas, reproduzindo assim a agricultura convencional. Contudo, vê-se a necessidade de uma nova abordagem, onde sejam valorizados os saberes locais, indo contra o sistema de desenvolvimento homogêneo para a consolidação de um modelo que seja mais sustentável.
Sistemas agroalimentares sustentáveis e saudáveis: reflexões a partir da perspectiva agroecológica
Authors: Fraga Ligia Kochhan de , Gonçalves Larisse Medeiros , Godoy Wilson Itamar , Outeiro Marlete Turmina
Published: November 2023

Um sistema alimentar saudável é aquele que, integrando o sistema produtivo agrícola e a nutrição, possibilita a produção e o consumo de alimentos nutritivos e acessíveis para todos, gerenciando adequadamente os recursos naturais, de modo a preservar os ecossistemas e garantir sustentabilidade, contudo, sob a ótica da ideologia neoliberal da globalização e do Estado mínimo, a alimentação, o mercado de terras e as empresas agroalimentares têm sido vistas como potenciais instrumentos financeiros, impactando negativamente sobre a sustentabilidade do sistema agroalimentar. Neste sentido, o presente trabalho tem como objetivo suscitar a reflexão acerca da insustentabilidade do modelo de produção agroalimentar hegemônico, os riscos associados à desconexão entre produção e consumo de alimentos, denotando a agroecologia como uma alternativa de produção sustentável em meio à crise socioambiental contemporânea. O presente manuscrito é um aporte teórico crítico, buscando lincar a literatura básica com artigos mais recentes. Apontamos entre as principais considerações inferidas aqui para a premência em se reestabelecer uma relação mais harmônica entre sociedade e natureza, superando o distanciamento e a ideia de domínio absoluto do homem sobre a natureza. Ademais, reconectar produção e consumo de alimentos é imprescindível, visto os inúmeros agravos à saúde e ao meio ambiente que se desenvolveram com a ascensão dos impérios agroalimentares e os riscos que ainda desconhecemos. Riscos à saúde, riscos ambientais, sociais e econômicos. Ao desconectar a produção do consumo de alimentos, perde-se a soberania alimentar, perdendo consequentemente a autonomia de escolha e a segurança alimentar e nutricional.
Meta-Analysis: Effects of Hormonal Contraceptive Use and History of Sexually Transmitted Disease on the Risk of Cervical Cancer
Authors: Damayanti Siti , Budihastuti Uki Retno , Murti Bhisma
Published: November 2023

Background: Cervical cancer is a sexually transmitted disease (STD) with the fourth largest number of new cases and deaths worldwide. This study aimed to analyze the effects of the use of hormonal contraception and a history of STD on the risk of cervical cancer in women.
Subjects and Method: The meta-analysis was carried out using the PRISMA flowchart and the PICO model. Population: women of reproductive age. Intervention: use of hormonal contraception and history of sexually transmitted infections Comparison: not using hormonal contraception and history of sexually transmitted infections Outcome: Cervical Cancer. The process of searching for articles is by searching through online journal databases which include Google Scholar, Elsevier and PubMed. With keywords “oral pill” OR “1 month injection” OR “3 month injection” OR “implant” OR “hormonal contraception” AND “cervical cancer” OR “syphilis” OR “chlamydia” OR “herpes” OR “gonorrhea” OR ”HIV” AND “Sexually transmitted infections” AND “Cross sectional” AND aOR. Articles were selected using the PRISMA flow and data analysis using the Review Manager 5.3 application.
Results: This meta-analysis consisted of 12 articles from Africa and Asia . The total sample was 8,240. The use of hormonal contraception (aOR = 2.34; 95% CI= 1.83 to 4.66; p<0.001) and had history of STD (aOR = 1.97; 95% CI = 1.49 to 2.61; p<0.001) increased the risk of cervical cancer.
Conclusion: The use of hormonal contraception and has history of std increase the risk of cervical cancer.
Keywords: hormonal contraception, history of sexually transmitted infections, cervical cancer.
Correspondence: Siti Damayanti. Master’s Program in Public Health, Universitas Sebelas Maret. Jl. Ir Sutami No.36, Kentingan, Jebres, Surakarta 57126, Central Java, Indonesia. Email: Sitidamayanti269@gmail.­com.
SEESAWING: An Evaluation of the Educational Aspirations and Attainments of College-aged BIWOC
Authors: Gilkenson Sara
Published: November 2023

There are disparities in achievement for Black, Indigenous, and Women of Color
(BIWOC) both during college as well as beyond completion due to insufficient
preparation before matriculation. Researchers have attributed this struggle of aligning
attainment and aspiration to financial constraints, culture shock, and overcoming an
academic and social learning curve. However, many institutions have naively created
programming and scholarship to aid these barriers, yet retention and graduation rates
for BIWOC students are still lower than their white counterparts. These gaps that are
characterized by race and ethnicity are persistent, leading institutions to wonder how
effective their support systems are. This thesis study explores the voices of college-
aged BIWOC. It aims to educate universities on dismantling their group stereotypes of
BIWOC to adopt a more communal climate for students that treats BIWOC as
individuals rather than homogeneously.
The goal of this study is to support BIWOC students by educating universities on the
importance of intentional programming that includes being transparent about disparities
and why the programming exists altogether. This thesis uses reflexivity and qualitative
interviews with a sample of 15 BIWOC who had attended one or more college classes,
who are currently between the ages of 18 to 35, and who have lived in Rhode Island at
some point in their life to better understand the experience of BIWOC. Among the
sample size, an eclectic mix of colleges were represented including community
colleges, public universities, Historically Black Universities, Hispanic Serving
Institutions, Predominately White Institutions, and other private institutions. Zoom
interviews were held from December 2022-February 2023. They were recorded,
transcribed, and coded inductively and then the researcher analyzed the codes, noting
seven overarching themes: Educational Seesawing, Ignorance Fatigue, Heightened
Awareness of Disparities, Drive/Focus/Disposition, Family Influence, Literacy, and Self-
Limitation.
ON THE ROLE OF BASIC VALUES IN THE TEACHING OF THE RUSSIAN AS A FOREIGN LANGUAGE (ON THE EXAMPLE OF SPEAKERS OF ITALIAN AND RUSSIAN LINGUOCULTURES)
Authors:   Venice University Ca’Foscari, Nistratova Svetlana L.
Published: November 2023

The article is about the role of basic values of Russian and Italian linguacultures in teaching Russian as a foreign language. It considers the possibilities of using the results of a comparative study of common human values in teaching intercultural communication. The author describes the methods of studying and describing common human values, presents the data obtained through experimental research of specific values of the Russian and Italian linguacultures, and identifies common and nationally labeled elements.
The views, opinions and decision-making of UK-based paramedics on the use of pre-hospital 12-lead electrocardiograms in acute stroke patients: a qualitative interview study
Authors: Munro Scott , Cooke Debbie , Holah Janet , Quinn Tom
Published: November 2023

Introduction: A qualitative exploration into the views, opinions and decision-making of paramedics involved in undertaking pre-hospital 12-lead electrocardiograms (PHECGs) for stroke patients was undertaken, in order to gain a deeper understanding of the clinical and occupational
context that the paramedics work within, the acceptability of the paramedics in using PHECGs for stroke patients and the consequences and influences of their decision-making.Methods: Data were collected via semi-structured interviews and analysed using the framework method, with
the underpinning theoretical framework of cognitive continuum theory. A purposive sample of 14 paramedics was recruited and interviewed.Results: Five themes were generated from the analysis of the interviews: (1) ‘time is brain’: minimising delays and rapid transport
to definitive care; (2) barriers and facilitators to undertaking PHECGs for stroke patients; (3) recognising and gaining cues; (4) maintaining patient dignity, self-protection and fully informed consent; and (5) education, experience and engagement with evidence.Conclusion: The
study showed mixed views on the usefulness of PHECGs, but all participants agreed that PHECGs should not cause additional delays. Paramedic decision-making on recording PHECGs relies on intuitive and quasi-rational cognitive modes, and requires a number of clinical, logistical and ethical
considerations. The findings suggest careful consideration is needed of the benefits and potential drawbacks of incorporating PHECGs into pre-hospital stroke care.
Exploring paramedic professional identity
Authors: Hill Lawrence , Eaton Georgette
Published: November 2023

The notion of a paramedic (as a title protected in law) has recently entered its third decade, but the history of the paramedic is considerably older than that. Who are we as a profession? What does it mean to be a paramedic? What makes us who we are? These intriguing and yet seldom
asked philosophical questions are at the heart of this article, which is intended to provoke discussion and serve as a foundation for further inquiry into questions of identity and philosophy in paramedicine.Literature pertaining to paramedic professional identity was explored and contextualised
within current paramedic practice. Although the overall picture is complex, four key areas for discussion emerged: the history of the paramedic profession; role diversity; the influence of ambulance work; and the education and training of paramedics. The influence of ambulance work permeates
all areas, suggesting that it is central to the development of paramedic professional identity. This discussion article is an exploration of the unique contexts and experiences that are associated with the process of being and becoming for paramedics.
Sosialisasi K3 (Keselamatan dan Kesehatan Kerja) di Miing Bengkel Cunda
Authors: Rizki Muhammad Nuzan , Safriwardy Ferri , Masrullita Masrullita , Zulmiardi Zulmiardi , Habibi Muhammad , Nurlaila Rizka
Published: November 2023

Peningkatan jumlah kendaraan bermotor di Indonesia, terutama mobil, telah mendorong kebutuhan akan bengkel perawatan kendaraan. Namun, lingkungan kerja di bengkel mobil memiliki potensi risiko tinggi terhadap kecelakaan dan kesehatan pekerja. Sosialisasi Keselamatan dan Kesehatan Kerja (K3) bertujuan untuk melindungi karyawan bengkel dengan meningkatkan kesadaran tentang bahaya potensial dan langkah-langkah pencegahan. Melalui sosialisasi K3, budaya keselamatan dan kesehatan dapat dikembangkan di bengkel, menciptakan lingkungan kerja yang lebih aman dan sehat. Sosialisasi ini juga memberikan kesempatan untuk meningkatkan pengetahuan karyawan tentang risiko potensial dan cara menerapkan K3, yang dapat mengurangi biaya perawatan dan pemeliharaan mesin. Kegiatan ini diharapkan akan menciptakan lingkungan kerja yang lebih produktif dan berkelanjutan di bengkel kendaraan. Dari hasil sosialisasi K3 di Miing Bengkel dapat dilihat bahwa terjadi peningkatan yang cukup signifikan terhadap pemahaman peserta sosialisasi. Sehingga dapat disimpulkan bahwa kegiatan sosialisasi ini memiliki dampak yang sangat besar untuk meningkatkan pemahaman peserta dalam penerapan K3 di lingkungan bengkel. Jika peserta memiliki tingkat pemahaman yang baik/tinggi terhadap pentingnya penerapan K3 saat bekerja, maka dapat meminimalisir terciptanya kondisi tidak aman saat bekerja sehingga dapat menurunkan angka kecelakaan kerja di lingkungan bengkel. Oleh karena itu, kegiatan sosialisasi ini direncanakan akan terus dilakukan dan dikembangkan, agar cakupan peserta semakin banyak.  Sehingga akan membantu masyarakat untuk meningkatkan standar keselamatan dan Kesehatan kerja dalam berkegiatan sehari-hari.