bluuebunny/crossref_metadata_2025 huggingface dataset:
A Review of Complementary and Alternative Medicine Therapies on Muscular Atrophy: A Literature Review of In Vivo/In Vitro Studies
Authors: Jeong Seong-Mok , Seo Byung-Kwan , Park Yeon-Cheol , Baek Yong-Hyeon
Published: November 2018

Objective. The objective of this review is to evaluate the recent treatment and study trends of complementary and alternative medicine (CAM) treatments on muscular atrophy by reviewing in vivo/in vitro studies. Materials and Methods. The searches were conducted via electronic databases including PubMed, the Cochrane Library, China National Knowledge Infrastructure (CNKI), Wanfang MED, and five Korean databases. Only in vivo and in vitro studies were included in this study. Results. A total of 44 studies (27 in vivo studies, 8 in vitro studies, and 9 in vivo with in vitro) were included. No serious maternal or fetal complications occurred. There were various animal models induced with muscular atrophy through “hindlimb suspension”, “nerve damage”, ‘alcohol or dexamethasone treatment’, “diabetes”, “CKD”, “stroke”, “cancer”, “genetic modification”, etc. In 28 of 36 articles measuring muscle mass, CAM significantly increased the mass. Additionally, 10 of them showed significant improvement in muscle function. In most in vitro studies, significant increases in both the diameter of myotubes and muscle cell numbers were reported. The mechanisms of action of protein synthesis, degradation, autophagy, and apoptotic markers were also investigated. Conclusions. These results demonstrate that CAM could prevent muscular atrophy. Further studies about CAM on muscular atrophy are needed.
Pure Well-Differentiated Adenocarcinoma Is a Safe Factor for Lymph Node Metastasis in T1 and T2 Colorectal Cancer: A Pilot Study
Authors: Yoshida Naohisa , Nakanishi Masayoshi , Inoue Ken , Yasuda Ritsu , Hirose Ryohei , Naito Yuji , Itoh Yoshito , Arita Tomohiro , Murayama Yasutoshi , Kuriu Yoshiaki , Otsuji Eigo , Yanagisawa Akio , Ogiso Kiyoshi , Murakami Takaaki , Morinaga Yukiko , Konishi Eiichi , Inada Yutaka , Kishimoto Mitsuo
Published: November 2018

Background and Aims. Various risk factors for lymph node metastasis (LNM) have been reported in colorectal T1 cancers. However, the factors available are insufficient for predicting LNM. We therefore investigated the utility of the new histological factor “pure well-differentiated adenocarcinoma” (PWDA) as a safe factor for predicting LNM in T1 and T2 cancers. Materials and Methods. We reviewed 115 T2 cancers and 202 T1 cancers in patients who underwent surgical resection in our center. We investigated the rates of LNM among various clinicopathological factors, including PWDA. PWDA was defined as a lesion comprising only well-differentiated adenocarcinoma. The consistency of the diagnosis of PWDA was evaluated among two pathologists. In addition, 72 T1 cancers with LNM from 8 related hospitals over 10 years (2008–2017) were also analyzed. Results. The rates of LNM and PWDA were 23.5% and 20.0%, respectively, in T2 cancers. Significant differences were noted between patients with and without LNM regarding lymphatic invasion (81.5% vs. 36.4%, p<0.001), poor histology (51.9% vs. 19.3%, p=0.008), and PWDA (3.7% vs. 25.0%, p=0.015). The rates of LNM and PWDA were 8.4% and 36.1%, respectively, in T1 cancers. Regarding the 73 PWDA cases and 129 non-PWDA cases, the rates of LNM were 0.0% and 13.2%, respectively (p<0.001). Among the 97 cases with lymphatic or venous invasion, the rates of LNM in 29 PWDA cases and 68 non-PWDA were 0% and 14.7%, respectively (p=0.029). The agreement of the two pathologists for the diagnosis of PWDA was acceptable (kappa value > 0.5). A multicenter review showed no cases of PWDA among 72 T1 cancers with LNM. Conclusions. PWDA is considered to be a safe factor for LNM in T1 cancer.
Analysis of Immune Responses in Mice Orally Immunized with Recombinant pMG36e-SP-TSOL18/Lactococcus lactisand pMG36e-TSOL18/Lactococcus lactisVaccines ofTaenia solium
Authors: Zhou Bi Ying , Sun Jun Chao , Li Xiang , Zhang Yue , Luo Bo , Jiang Nan , Liu Mei Chen
Published: November 2018

Cysticercosis is a cosmopolitan zoonotic parasitic disease infected by larval ofTaenia solium(T. solium). Several drugs for the treatment of cysticercosis, such as praziquantel, albendazole, and mebendazole, have certain toxicity and side effects. Considering that there is no vaccine available, we studied a new vaccine for cysticercosis in this study. The completeTSOL18gene and the optimizedSP-TSOL18gene fragments were obtained using PCR-based accurate synthesis method. The secretory and intracellular recombinant pMG36e-SP-TSOL18/Lactococcus lactis(L. lactis) and pMG36e-TSOL18/L. lactisvaccines ofT. soliumwere prepared. Immune responses in mice orally immunized with these two recombinantL. lactisvaccines were analyzed by the determination of specific antibodies (IgG, IgG1, IgG2a, and sIgA) in serum, spleen lymphocyte proliferation, and cytokines (IL-2, IFN-γ, IL-4, and IL-10) in spleen lymphocyte culture supernatant. Our results showed that, after the first immunization, in these two recombinantL. lactisvaccine groups, the levels of serum specific IgG, IgG2a, and IgG1 increased on 14–56 d and reached the highest level on days 42, 42, and 28, respectively. The level of specific sIgA of intestinal mucosa also increased on 14–56 d and reached the highest level on day 42. The level of spleen lymphocyte proliferation increased on 14–56 d and reached the highest level on day 42. The levels of IL-2, IFN-γ, IL-4, and IL-10 in spleen lymphocyte culture supernatant increased on 14–56 d and reached the highest level on days 42, 42, 28, and 28, respectively. These results indicated that the recombinant pMG36e-SP-TSOL18/L. lactisand pMG36e-TSOL18/L. lactisvaccines can induce specific cellular, humoral, and mucosal immune responses in mice with oral vaccination. More importantly, the recombinant pMG36e-SP-TSOL18/L. lactisvaccine has a better immune effect. In summary, these results demonstrated the possibility of usingL. lactisstrain as a vector to deliver protective antigens ofT. solium.
Symptomatic Primary Hyperparathyroidism as a Risk Factor for Differentiated Thyroid Cancer
Authors: Vargas-Ortega Guadalupe , Balcázar-Hernández Lourdes , González-Virla Baldomero , Ramírez-Rentería Claudia , Nieto-Guzmán Oriana , Garrido-Mendoza Ana Pamela , Flores-Maya Marco Antonio , Mercado Moisés , Victoria Mendoza-Zubieta
Published: November 2018

Background. The primary hyperparathyroidism (PHPT) is a common disease for the endocrinologist. The concomitant thyroid disease and differentiated thyroid cancer (DTC) appear to be more frequent in patients with PHPT than in the general population. The aim of this study was to characterize patients with symptomatic PHPT with and without DTC and analyze frequency and risk factors.Methods. We consecutively studied patients with symptomatic PHPT diagnosed and treated at our center between 2013 and 2015. Patients with subclinical and syndromic forms of PHPT were excluded. Clinical and biochemical characteristics of patients with and without DTC were compared and risk factors were determined. All patients were studied with thyroid ultrasound and thyroid gammagraphy with TC-MIBI. Two expert surgeons performed all the surgical procedures.Results. In 59 patients included, we found 12 cases of PTC (20.3%). The final histopathological report of the PTC was 7 cases of follicular variant, 2 cases of oncocytic variant, 2 cases of classic variant, and 1 case of columnar cells variant of PTC. Patients with thyroid cancer were older than patients without thyroid cancer (62 ± 9.5 versus 52 ± 15.8, p = 0.03). Higher preoperative levels of iPTH were associated with PTC (p=0.03) [OR 5.16 (95% CI: 1.08-24.7)].Conclusion. PTC is frequent in patients with symptomatic PHPT. Thyroid nodules in patients with symptomatic PHPT must be studied before parathyroidectomy. In symptomatic PHPT, higher level concentration of parathormone (PTH) was associated with higher risk of DTC.
Predicting Discharge Location among Low-Energy Hip Fracture Patients Using the Score for Trauma Triage in the Geriatric and Middle-Aged (STTGMA)
Authors: Konda Sanjit R. , Saleh Hesham , Lott Ariana , Egol Kenneth A.
Published: November 2018

Patterns of discharge location may be evident based on the “sickness” profile of the patient. This study sought to evaluate the ability of the STTGMA tool, a validated mortality risk index for middle-aged and geriatric trauma patients, to predict discharge location in a cohort of low-energy elderly hip fracture patients, with successful discharge planning measured by readmission rates. Low-energy hip fracture patients aged 55 years and older were prospectively followed throughout their hospitalization. On initial evaluation in the Emergency Department, each patient’s age, comorbidities, injury severity, and functional status were utilized to calculate a STTGMA score. Discharge location was recorded with the primary outcome measure of an unsuccessful discharge being readmission within 30 days. Patients were risk stratified into minimal-, low-, moderate-, and high-risk STTGMA cohorts. A p-value of <0.05 was considered significant for all statistical tests. 408 low-energy hip fractures were enrolled in the study with a mean age of 81.3±10.6 years. There were 214 (52.5%) intertrochanteric fractures, 167 (40.9%) femoral neck fractures, and 27 (6.6%) subtrochanteric femur fractures. There was no difference in readmission rates within STTGMA risk cohorts with respect to discharge location; however, among individual discharge locations there was significant variation in readmission rates when patients were risk stratified. Overall, STTGMA risk cohorts appeared to adequately risk-stratify readmission with 3.5% of minimal-risk patients experiencing readmission compared to 24.5% of moderate-risk patients. Specific cohorts deemed high-risk for readmission were adequately identified. The STTGMA tool allows for prediction of unfavorable discharge location in hip fracture patients. Based on observations made via the STTGMA tool, improvements in discharge planning can be undertaken to increase home discharge and to more closely track “high-risk” discharges to help prevent readmissions.
Insights into Endothelial Progenitor Cells: Origin, Classification, Potentials, and Prospects
Authors: Chopra H. , Hung M. K. , Kwong D. L. , Zhang C. F. , Pow E. H. N.
Published: November 2018

With the discovery of endothelial progenitor cells (EPCs) in the late 1990s, a paradigm shift in the concept of neoangiogenesis occurred. The identification of circulating EPCs in peripheral blood marked the beginning of a new era with enormous potential in the rapidly transforming regenerative field. Overwhelmed with the revelation, researchers across the globe focused on isolating, defining, and interpreting the role of EPCs in various physiological and pathological conditions. Consequently, controversies emerged regarding the isolation techniques and classification of EPCs. Nevertheless, the potential of using EPCs in tissue engineering as an angiogenic source has been extensively explored. Concomitantly, the impact of EPCs on various diseases, such as diabetes, cancer, and cardiovascular diseases, has been studied. Within the limitations of the current knowledge, this review attempts to delineate the concept of EPCs in a sequential manner from the speculative history to a definitive presence (origin, sources of EPCs, isolation, and identification) and significance of these EPCs. Additionally, this review is aimed at serving as a guide for investigators, identifying potential research gaps, and summarizing our current and future prospects regarding EPCs.
A Sociologia da Educação de Bourdieu na revista Actes de la Recherche en Sciences Sociales
Authors: Hey Ana Paula , Catani Afrânio Mendes , Medeiros Cristina Carta Cardoso de
Published: November 2018

O texto apresenta uma incursão pelos artigos sobre educação do sociólogo francês Pierre Bourdieu (1930-2002) publicados na revista Actes de la Recherche en Sciences Sociales (ARSS). Fundada por Bourdieu em 1975 e dirigida por ele até a sua morte, a ARSS acolheu onze de seus artigos na temática educacional (sendo quatro em co-autoria) entre 1975 e 2000. Ressalta-se que nas páginas do periódico o autor “rascunhou” vários trabalhos que viriam a se constituir em seus livros. Nos textos ali apresentados Bourdieu reafirma a relevância da sociologia da educação como um capítulo importante da sociologia do conhecimento e da sociologia do poder, fornecendo um verdadeiro programa de investigação para enxergar os mecanismos instituídos de produção da dominação e das estratégias de reprodução nas sociedades de classes contemporâneas.
Dios nos salve de las ciencias sociales: os relatórios de Ernesto Quesada e o debate sobre as humanidades nas universidades argentinas
Authors: Tedesco Alexandra Dias Ferraz
Published: November 2018

A partir da análise de três relatórios elaborados pelo professor Ernesto Quesada, este artigo almeja refletir acerca das tensões entre os principais projetos intelectuais em debate na Argentina das primeiras décadas do século XX: as análises de orientação positivista (reivindicando, duplamente, uma aposta teórica e uma visão de organização universitária) e aquelas ligadas à preservação de uma “cultura do espírito”, conectada aos discursos fundacionais do campo universitário argentino. Observou-se que, através da análise dos relatórios, é possível capturar uma dimensão do debate que ultrapassa as contendas teóricas e aciona a necessidade de reflexão acerca das disputas disciplinares no campo universitário.
Reflecting in/on field theory in practice
Authors: Grenfell Michael
Published: November 2018

The article discuses the dimension of reflexivity within the work of the social theorist Pierre Bourdieu. It alludes to the provenance of Bourdieu’s theory of practice and the epistemology, which underpins it. Language is a key element in reflexivity, the article therefore outline’s Bourdieu approach to language and the significance it holds in the development of his key concepts, as well as the relationship between subject and object. Reference is made to the works of Habermas, Heidegger, Merleau-Ponty and others to offer a ground base in just what Bourdieusian reflexivity is and how it operates in practice. Phases and stages in methodology are referred to as well as how reflexivity should operate within them. Finally, the significance of the discussion is underlined with reference to consequent outcomes.
Chesnais, François. Finance Capital Today: Corporations and Banks in the Lasting Global Slump
Authors: Lapyda Ilan
Published: November 2018

Resenha do livro Finance Capital Today: Corporations and Banks in the Lasting Global Slump, Boston, Brill Academica Pub., 2016, de François Chesnais
Pinheiro-Machado, Rosana. Counterfeit Itineraries in the Global South: The human consequences of piracy in China and Brazil
Authors: Piza Douglas de Toledo
Published: November 2018

Book Review: Counterfeit Itineraries in the Global South: The human consequences of piracy in China and Brazil, London and New York, Routledge, 2017, by Rosana Pinheiro-Machado
Turismo en automóvil en Argentina (1920-1950)
Authors: Piglia Melina
Published: November 2018

A Argentina chegou a ser, no período entre guerras, o país latino-americano com mais automóveis. Sua acelerada difusão implicou também o advento de uma nova cultura do automóvel. A partir da análise de documentos primários (imprensa, guias de viagem, fotografias) e numa perspectiva histórica das mobilidades, este trabalho analisa a configuração do turismo em automóvel como uma nova prática de lazer e consumo, na primeira metade do século XX na Argentina, como parte de um processo em que se entrelaçaram a democratização social do consumo de automóveis, a expansão do turismo nacional, a transformação técnica dos veículos e a construção de infraestrutura viária.
Cidades, práticas e representações em movimento: notas para uma análise cultural da mobilidade como experiência urbana
Authors: Zunino Singh Dhan
Published: November 2018

Neste ensaio, introduzem-se noções-chave sobre o “giro móvel” para compreender e definir a experiência de mobilidade urbana, com base em uma crítica aos estudos urbanos e de transporte, bem como às ciências sociais em geral, e na América Latina em particular. Propõe-se que as cidades são espaços para circulação, destacando a importância que esta tem na produção do espaço urbano. Ainda que a tradição da teoria social moderna tenha sustentado a ideia de que os espaços de trânsito são não lugares, os deslocamentos na cidade são formas de habitar e toda mobilidade é uma prática social com sentido. Por fim, a experiência de mobilidade urbana é caracterizada através de exemplos concretos, como a automobilidade.
Turismos Diaspóricos: Mapeando Conceitos e Questões
Authors: Pinho Patricia de Santana
Published: November 2018

O estudo do turismo nas ciências sociais possui hoje o reconhecimento merecido e já não é mais necessário comprovar a sua relevância para o entendimento das sociedades e culturas, principalmente em um mundo marcado pela intensificação das mobilidades. No entanto, algumas das vertentes do turismo, como o turismo sexual e o ecoturismo, têm sido mais estudadas do que outras. Este artigo visa contribuir para o desenvolvimento do estudo dos turismos diaspóricos, que têm atraído um interesse cada vez maior de viajantes e pesquisadores. Analisando as interseções entre turismo, diáspora e raça, o artigo tem dois objetivos centrais: mapear os principais conceitos que têm sido utilizados nas análises dos turismos diaspóricos e discutir algumas das suas questões centrais. A apresentação dos conceitos não tem um intuito meramente taxonômico, visando, em vez disso, gerar ferramentas que possam aprofundar as análises. Já as questões aqui discutidas, embora não abranjam a totalidade das experiências diaspóricas do turismo, indicam alguns dos principais caminhos a serem percorridos nesses estudos, tais como as análises sobre as conexões entre turismo e identidades, as hierarquias inerentes a diásporas e os paradoxos da mobilidade privilegiada de turistas pertencentes a grupos raciais subordinados.
Theorising mobility justice
Authors: Sheller Mimi
Published: November 2018

Mobility justice is one of the crucial political and ethical issues of our day, when the entire world faces the urgent question of how to make the transition to more environmentally sustainable and socially just mobilities. All around the planet urban, regional, and international governing bodies are grappling with a series of crises related to how we move: an urban crisis of pollution and congestion, a global refugee crisis of borders and humanitarianism, and a climate crisis of global warming and decarbonisation. This article seeks to think across these crises showing how each is part of a wider disturbance in prevailing institutions concerned with the management of mobilities and immobilities. Mobility justice offers a new way to think across the micro and macro scale of transitioning toward more just mobilities.
AS TESSITURAS DA LIBERDADE NO PERNAMBUCO OITOCENTISTA (RECIFE: 1883 E 1884)
Authors: Silva José Bento Rosa da
Published: November 2018

O artigo investiga dois processos cíveis envolvendo africanos e crioulos na cidade do Recife, nos anos de 1883 e 1884. No primeiro processo analisado, uma escravizada reivindica sua liberdade, a partir do argumento de que era africana livre, pois que desembarcara no Império do Brasil após a Lei de 7 de novembro de 1831. O processo revela que outros africanos desembarcaram com ela no mesmo navio negreiro na região do Cabo de Santo Agostinho. Esses malungos – companheiros de barco – foram as testemunhas no processo movido contra a senhora de Maria, corroborando a tese de que era uma africana livre. O segundo processo é emblemático, trata- se de uma mãe brigando na justiça contra a reescravização de sua filha, que teria o direito à liberdade por haver sido abandonada por sua senhora, em virtude de estar doente. Amparada na Lei de 28 de setembro de 1871, ela busca o direito à liberdade da filha.
Aplicação de entrevistas cognitivas para produção de versões brasileiras de instrumentos de avaliação da prática centrada na família
Authors: Vaz Daniela Virginia , Silva Dayana Karen Esteves da , Campos Débora Silva , Antunes Ana Amélia Moraes , Magalhães Lívia de Castro , Furtado Sheyla Rossana Cavalcanti
Published: November 2018

A Prática Centrada na Família (PCF), considerada como best practice na assistência à criança, é um conjunto de atitudes e valores que reconhece a família como centro do cuidado. A MPOC-20 e MPOC-SP são questionários que avaliam a percepção dos cuidadores e dos profissionais de saúde, acerca da PCF. Este trabalho descreve o processo de tradução e adaptação transcultural dos instrumentos para o português brasileiro. A tradução deve garantir total compreensão das questões pelos entrevistados, assim, para avaliar essa compreensão utilizamos como ferramenta a entrevista cognitiva. Foram identificados problemas de compreensão em ambos os questionários, e foram feitos ajustes para solucioná-los. O uso da entrevista cognitiva foi fundamental para o processo de tradução e adaptação transcultural dos questionários.
Trabalhadores em processo de reabilitação profissional
Authors: Figueiredo Mirela de Oliveira , Silva Lurian Rodrigues , Daidone Vitória , Magalhães Lilian
Published: November 2018

Esta pesquisa teve como objetivo verificar a percepção de trabalhadores submetidos à reabilitação profissional por meio da intervenção grupal desenvolvida pela terapia ocupacional. O estudo foi qualitativo e utilizou a análise temática. Foram realizadas entrevistas semi-estruturadas, com 5 trabalhadores afastados por distúrbios músculo-esqueléticos e em reabilitação profissional no INSS de São Carlos – SP. Os participantes mencionaram que a intervenção em grupos é realizada por meio de diferentes atividades como simulação de provas escolares (acesso à educação superior), entrevistas de emprego, discussões sobre perspectivas para o futuro, profissionais e consultoria com trabalhadores que passaram pelo programa e pelas intervenções em grupo. Também foi relatado que a intervenção em grupo, proposta pela terapia ocupacional, é de grande importância, pois fornece orientação, estimula a aprendizagem, promove qualificação profissional e a reabilitação vocacional. Além desses aspectos práticos e dos benefícios para a reabilitação, os participantes declararam que os grupos oferecem bem-estar emocional, satisfação pessoal e redução de pensamentos negativos e sentimentos inadequados.
Desafios enfrentados por usuários da saúde mental
Authors: Luiz Carolina Con Andrades , Leal Erotildes Maria , Galletti Maria Cecília
Published: November 2018

Este artigo é extraído de pesquisa de mestrado cujo objetivo foi conhecer a experiência de trabalho de usuários da saúde mental em oficinas de geração de trabalho e renda na cidade de Campinas, São Paulo. Tratou-se de pesquisa qualitativa, dentro da perspectiva da pesquisa social, foram realizados grupos focais com participantes das oficinas do NOT (Núcleo de Oficinas e Trabalho), todos os seis participantes tiveram experiências de trabalho anteriores a entrada nas oficinas e trazem algumas experiências de violência, humilhação e submissão em situações de trabalho dentro do modelo capitalista. Neste artigo traremos as narrativas de oficineiros, que nos possibilitam conhecer o cotidiano de trabalho nas oficinas de geração de trabalho e renda na perspectiva dos usuários participantes. O trabalho, nos moldes capitalistas, não contribui para a inclusão de pessoas em processo de vulnerabilidade social. O entendimento do trabalho dos usuários da saúde mental como direito de cidadania e o encontro dos princípios da reforma psiquiátrica e da economia solidária, são fundamentais para a construção de espaços de trabalho dignos e de superação do preconceito e estigma.
Novos olhares para outros modos de existência
Authors: Ferreira Thayane Pereira da Silva , Sampaio Juliana , Gomes Luciano Bezerra
Published: November 2018

O artigo discute a potência da produção de novas visibilidades sobre pessoas com transtorno mental que reconheçam outros modos de existência. O percurso metodológico se deu a partir do encontro e suas afecções no qual os pesquisadores misturaram-se ao mundo pesquisado. Caracteriza-se como um estudo de caso, desenvolvido entre equipes de saúde, durante fevereiro a dezembro de 2015 no município de João Pessoa-PB. O caminhar cartográfico aponta o olhar inicial das equipes de saúde sobre a família, suas ofertas terapêuticas e o deslocamento dos olhares sobre os sujeitos. Este acompanhamento nos revelou que os sujeitos produzem infinitas conexões de vida, com, sem, ou mesmo apesar, dos profissionais de saúde. Produzir um cuidado que reconheça e legitime a autonomia do sujeito no seu modo de levar sua vida, implica em reconhecê-lo protagonista de sua história.
Perfil sensorial e sua relação com risco psíquico, prematuridade e desenvolvimento motor e de linguagem por bebês de 12 meses
Authors: Beltrame Vitória Hoerbe , Moraes Anaelena Bragança de , Souza Ana Paula Ramos de
Published: November 2018

Objetivo: Analisar a correlação entre perfil sensorial do bebê, idade gestacional e risco psíquico e seus efeitos na avaliação motora e de linguagem. Método: a amostra foi composta por 40 bebês, 20 prematuros e 20 nascidos a termo, com 10 bebês com risco psíquico e 10 sem risco em cada grupo, identificados a partir dos sinais PREAUT e dos Indicadores Clínicos de Referência ao Desenvolvimento Infantil e avaliados pelo DENVER II, na faixa etária de 12 meses a 12 meses e 29 dias. A análise estatística foi realizada pelos programas STATISTICA 9.1 e PASW 17.0. Resultados: Foi identificada significância estatística nas correlações entre testes sensoriais e protocolo de risco psíquico, bem como no fator de risco prematuridade. Os resultados não demonstraram significância estatística com os resultados em motricidade e linguagem no teste DENVER II. Conclusão: Alterações no perfil sensorial estiveram relacionadas a risco psíquico e idade gestacional menor, mas não se correlacionaram ao desenvolvimento motor e linguístico.
significado das ocupações cotidianas
Authors: Hasselkus Betty Risteen
Published: November 2018

Apresentamos na seção “Ponto de Vista” o artigo “O significado das ocupações cotidianas: pesquisa e prática”, escrito pela doutora Betty Risteen Hasselkus, professora emérita de terapia ocupacional da Universidade de Wisconsin-Madison e autora do livro The meaning of everyday occupation (2 ed., 2011). No texto, ela traz cenas de sua prática profissional articuladas a sua compreensão do significado das ocupações cotidianas como norteador da prática da Terapia Ocupacional.
prática de registros em Terapia Ocupacional
Authors: Bombarda Tatiana Barbieri , Moreira Mauricio de Souza , Dahdah Daniel Ferreira , Marcolino Taís Quevedo , Joaquim Regina Helena Vitale Torkomian
Published: November 2018

Este artigo busca tecer reflexões a partir dos fundamentos técnico-legais da resolução do Conselho Federal de Fisioterapia e Terapia Ocupacional (COFFITO), número 415, sancionada em 2012, a qual regulamenta o procedimento do registro terapêutico ocupacional em prontuário. Apresentamos o estado da arte das pesquisas sobre registro em prontuário no Brasil, as relações entre o raciocínio clínico/terapêutico e seu registro e as diretrizes da resolução COFFITO-415 de modo a elucidar tensionamentos, fragilidades e dar destaque às potências do registro em prontuário. Além disso, o artigo busca trabalhar alguns aspectos práticos para ampliar a prática de registro em prontuário na área.
Retrospective evaluation of a local protocol used to enhance laboratory savings through minimizing the performance of alkaline phosphatase isoenzyme analysis
Authors: Haji Saliha MI , Chipchase Allison , Fraser William D , Gomez Javier
Published: November 2018

Background

Alkaline phosphatase isoenzyme analysis is an expensive and time-consuming laboratory test. We evaluated the effect of a locally derived screening algorithm for alkaline phosphatase isoenzyme requests on the number of alkaline phosphatase isoenzyme analyses performed, laboratory cost and patient care.

Method

A total of 110 alkaline phosphatase isoenzyme analysis requests from the year 2015 were reviewed and subsequent alkaline phosphatase concentrations were monitored over a two-year period, to determine if the decision of performing/not performing alkaline phosphatase isoenzyme analysis, based on the algorithm, had an impact on patient care and laboratory cost. All alkaline phosphatase isoenzyme analysis requests with two consecutive elevated alkaline phosphatase concentrations (>upper limit of reference interval) were screened and, subject to the gamma glutamyl transferase being within the reference interval, either Bone alkaline phosphatase or 25 hydroxyvitamin D was measured depending on the age of the patient.

Results

Compliance with this algorithm led to the normalization of subsequent serum alkaline phosphatase in 97% of patients without requiring alkaline phosphatase isoenzyme analysis. The cost of performing Bone alkaline phosphatase and 25 hydroxyvitamin D in-house was £778.50, while the cost of performing alkaline phosphatase isoenzyme analysis would have been £3040. This resulted in a laboratory saving of £2261.50.

Conclusions

Implementation of this algorithm led to a significant reduction in alkaline phosphatase isoenzyme analysis, without compromising patient care. Total savings could be increased if 25 hydroxyvitamin D was used as a first-line test, for all patients with an elevated alkaline phosphatase and a normal gamma glutamyl transferase regardless of age. This algorithm is cost-effective and can be implemented in laboratories with 25 hydroxyvitamin D assay.
Investigation of time-dependent behavior of sandwich panel with poly vinyl carbon foam and fiber glass/epoxy faces
Authors: Karami Ahmad , Ranji Ahmad Rahbar , Mirghaderi Hamid R
Published: November 2018

The main purpose of this study is to investigate the time-dependent behavior of a sandwich panel numerically and experimentally. The core of the panel is made of poly vinyl carbon Airex 70.75, and shells are made by vacuum injection method from 600 g glass fiber per square meter. To determine the time-dependent compressive and shear modulus of the core, dynamic tests are performed at different temperatures. Using appropriate equations, time-dependent Bulk modulus and Poison's ratio are calculated. Performing three-point-bend tests on sandwich panels, time-dependent behavior of this material is investigated. Finally, these three-point-bend tests are simulated using finite element method and calculated values of viscoelastic parameters. Accordingly, numerical simulation results are compared with experimental data. Regarding the well matching of the quasi-static model, modeling of the relaxation behavior of the beam sample is investigated.
Preparation and evaluation of thermo-regulating bamboo fabric treated by microencapsulated phase change materials
Authors: Zhang Guoqing , Cai Changwei , Wang Yilai , Liu Guojin , Zhou Lan , Yao Juming , Militky Jiri , Marek Jaromir , Venkataraman Mohanapriya , Zhu Guocheng
Published: November 2018

Two types of microencapsulated phase change materials (ENPCMs) were synthesized by polymerization. The core material of ENPCM was n-octadecane and the shell materials were polymethyl methacrylate-butyl acrylate and polymethyl methacrylate-butyl acrylate-hydroxyethyl methacrylate. Subsequently, the synthesized ENPCMs were applied onto bamboo fabric by the dip and dry method. The properties of ENPCMs were analyzed in terms of surface morphology, size distribution and latent heat; the treated bamboo fabrics were evaluated in terms of surface morphology, hydrophilicity, washing fastness and heat storage capacity. The results showed that polymethyl methacrylate-butyl acrylate/ n-octadecane (PMBO) microcapsules had an irregular shape, while polymethyl methacrylate-butyl acrylate-hydroxyethyl methacrylate/ n-octadecane (PMBHO) microcapsules were spherical, and the mean diameters of both microcapsules were less than 1 µm. The latent heat of phase change material (PCM) microcapsules was almost the same at a thermal storage capacity of 110 J/g. There were many more and more even PMBHO microcapsules deposited on bamboo fabric than that of PMBO microcapsules deposited on bamboo fabric. Bamboo fabrics treated by both microcapsules were hydrophilic, and the hydrophilicity of fabric treated by PMBHO microcapsules was even better. The ratio of PCM microcapsules to bamboo fabric was about 1:4, and the latent heat of treated bamboo fabrics was about 20 J/g. Moreover, the treated bamboo fabrics exhibited excellent washing fastness due to the strong binding strength between the highly hydrophilic microcapsules and bamboo fibers. Approximately 72% of PCM microcapsules were retained on the fabric after 15 washing cycles.
Hot dry rock geothermal resource potential in the Wudalianchi volcanic field, NE CHINA: Implications from geophysical exploration
Authors: Shengtao Li , Tianfu Xu , Senqi Zhang , Xiaofeng Jia , Puyuan Tian , Dongdong Yue , Qiuxia Zhang , Bo Feng , Zhaolong Feng
Published: November 2018

Hot dry rock is regarded as the clean energy of the future and is an important part of geothermal resources, with great research value and development prospects. The Weishan volcano, located in the northern part of the Wudalianchi volcanic group, was formed in the Pleistocene, and its age is only (0.57–0.31) ± 0.05 Ma. This area has a geothermal setting similar to but a younger age than that of the Fenton Hill volcano (formed 1.40–1.10 Ma) where a hot dry rock power project has operated since 1973. In this study, we used ambient noise tomography and magnetotelluric sounding methods to investigate deep heat sources beneath the Weishan volcano. The results show good geothermal conditions for hot dry rock formation in this region. A cooling magma chamber that might be the hot dry rock heat source is indicated in the upper crust at 6.5–13 km depth, with a volume of ∼200 km3. Our study suggests that the monzonitic granites of the Indosinian Xiaohongshan unit, which lies beneath the Late Cretaceous Nenjiang Formation and the Neoproterozoic-Early Cambrian Beikuanhe Formation, should be the main target for further hot dry rock geothermal energy exploration and development.
Detecting impaired function of renal allografts at the early stage after transplantation using intravoxel incoherent motion imaging
Authors: Chen Lihua , Ren Tao , Zuo Panli , Fu Yingxin , Xia Shuang , Shen Wen
Published: November 2018

Background

Detecting renal allografts with impaired function early after renal transplantation and timely intervention are important to ensure a successful outcome.

Purpose

To detect impaired function of renal allografts at the early stage after renal transplantation using intravoxel incoherent motion imaging (IVIM).

Material and Methods

Forty-six recipients with good allograft function and 32 recipients with impaired function were included in this study. All participants were scanned with IVIM using 11 b-values on a 3-T magnetic resonance (MR) scanner; the apparent diffusion coefficient (ADC), ADC of slow diffusion (ADCslow), pseudo-diffusion (ADCfast), and perfusion fraction (f) values were calculated using a full bi-exponential model. Correlations between estimated glomerular filtration rate (eGFR) and the IVIM parameters were assessed by using Spearman correlation analysis. Receiver operating characteristics were used to assess the diagnostic utilities for detecting allografts with impaired function.

Results

The ADC, ADCslow, ADCfast, and f values of the renal cortex and the ADC and ADCslow values of the renal medulla were significantly higher in allografts with good function compared to those with impaired function (all P < 0.05). There was a significant corticomedullary difference in ADCslow, ADC, and f in all allografts. ADCfast values were higher in the cortex than in the medulla for allografts with good function but no differences were seen in allografts with impaired function ( P > 0.05). Combined use of all cortical IVIM parameters has higher efficacy in detecting renal allograft dysfunction than any single parameter (sensitivity = 90.62%; speciﬁcity = 78.26%).

Conclusion

IVIM technique may be useful for detecting renal allograft dysfunction, especially combined use of cortical parameters.
Acute migraine therapy with external trigeminal neurostimulation (ACME): A randomized controlled trial
Authors: Chou Denise E , Shnayderman Yugrakh Marianna , Winegarner Dana , Rowe Vernon , Kuruvilla Deena , Schoenen Jean
Published: November 2018

Objective

To assess the safety and efficacy of external trigeminal nerve stimulation for acute pain relief during migraine attacks with or without aura via a sham-controlled trial.

Methods

This was a double-blind, randomized, sham-controlled study conducted across three headache centers in the United States. Adult patients who were experiencing an acute migraine attack with or without aura were recruited on site and randomly assigned 1:1 to receive either verum or sham external trigeminal nerve stimulation treatment (CEFALY Technology) for 1 hour. Pain intensity was scored using a visual analogue scale (0 = no pain to 10 = maximum pain). The primary outcome measure was the mean change in pain intensity at 1 hour compared to baseline.

Results

A total of 109 participants were screened between February 1, 2016 and March 31, 2017. Of these, 106 patients were randomized and included in the intention-to-treat analysis (verum: n = 52; sham: n = 54). The primary outcome measure was significantly more reduced in the verum group than in the sham group: −3.46 ± 2.32 versus −1.78 ± 1.89 ( p < 0.0001), or −59% versus −30% ( p < 0.0001). With regards to migraine subgroups, there was a significant difference in pain reduction between verum and sham for ‘migraine without aura’ attacks: mean visual analogue scale reduction at 1 hour was −3.3 ± 2.4 for the verum group versus −1.7 ± 1.9 for the sham group ( p = 0.0006). For ‘migraine with aura’ attacks, pain reduction was numerically greater for verum versus sham, but did not reach significance: mean visual analogue scale reduction at 1 hour was −4.3 ± 1.8 for the verum group versus −2.6 ± 1.9 for the sham group ( p = 0.060). No serious adverse events were reported and five minor adverse events occurred in the verum group.

Conclusion

One-hour treatment with external trigeminal nerve stimulation resulted in significant headache pain relief compared to sham stimulation and was well tolerated, suggesting it may be a safe and effective acute treatment for migraine attacks.

Study protocol

ClinicalTrials.gov Identifier: NCT02590939.
Altered speech with migraine attacks: A prospective, longitudinal study of episodic migraine without aura
Authors: Schwedt Todd J , Peplinski Jacob , Garcia-Filion Pamela , Berisha Visar
Published: November 2018

Background and Objective

Some individuals with migraine report the presence of speech changes during their migraine attacks. The goal of this study was to compare objective features of speech during the migraine pre-attack, the migraine attack, and during the interictal period.

Methods

This was a prospective, longitudinal, observational study of adults with episodic migraine and healthy non-migraine controls. Participants provided speech samples three times per day using a speech elicitation tool included within a mobile app. Six complementary speech features that capture articulation and prosody were extracted from speech samples. Participants with migraine maintained a daily headache diary using the same app. A mixed effects model and t-tests were used to investigate differences in speech features between controls, the migraine pre-attack phase, the migraine attack, and the interictal period.

Results

In total, 56,767 speech samples were collected, including 43,102 from 15 individuals with migraine and 13,665 from matched healthy controls. Significant group-level differences in speech features were identified between those with migraine and healthy controls and within the migraine group during the pre-attack vs. attack vs. interictal periods (all p < .05). Most consistently, speech changes occurred in the speaking rate, articulation rate and precision, and phonatory duration. Within-subject analysis revealed that seven of 15 individuals with migraine showed significant change in at least one speech feature when comparing the migraine attack vs. interictal phase and four showed similar changes when comparing the pre-attack vs. interictal phases.

Conclusions

Changes in speech occurred in almost half of the individuals during migraine attacks. Once confirmed in subsequent studies, speech changes could be considered a feature of the migraine attack.
The effects of S-glass fiber hybridization on vibration-damping behavior of intraply woven carbon/aramid hybrid composites for different lay-up configurations
Authors: Bulut Mehmet , Alsaadi Mohamad , Erkliğ Ahmet , Alrawi Humam
Published: November 2018

In this study, the vibration and damping characteristics of the hybrid composites reinforced with plain woven S-glass and intraply woven carbon/Kevlar fiber fabrics are investigated. Vibration tests on the samples have been conducted only for measuring the first mode of natural frequency with application of experimental modal analysis procedures. Symmetric and asymmetric layering structures have been prepared for the hybrid composite configurations in order to study the stacking sequence effects. Damping ratios have been evaluated from the logarithmic decrement method by using acceleration–time envelope curves. Results have shown that position and percentage of the fibers in the composites are the most effective parameters for natural frequency and damping characteristics of hybrid samples, and some samples have shown the synergistic effects leading to a significant enhancement in damping and natural frequency.
Performance-based fault diagnosis of a gas turbine engine using an integrated support vector machine and artificial neural network method
Authors: Fentaye Amare Desalegn , Ul-Haq Gilani Syed Ihtsham , Baheta Aklilu Tesfamichael , Li Yi-Guang
Published: November 2018

An effective and reliable gas path diagnostic method that could be used to detect, isolate, and identify gas turbine degradations is crucial in a gas turbine condition-based maintenance. In this paper, we proposed a new combined technique of artificial neural network and support vector machine for a two-shaft industrial gas turbine engine gas path diagnostics. To this end, an autoassociative neural network is used as a preprocessor to minimize noise and generate necessary features, a nested support vector machine to classify gas path faults, and a multilayer perceptron to assess the magnitude of the faults. The necessary data to train and test the method are obtained from a performance model of the case engine under steady-state operating conditions. The test results indicate that the proposed method can diagnose both single- and multiple-component faults successfully and shows a clear advantage over some other methods in terms of multiple fault diagnosis. Moreover, 5-8 sets of measurements have been used to assess the prediction accuracy, and only a 2.3% difference was observed. This result indicates that the proposed method can be used for multiple fault diagnosis of gas turbines with limited measurements.
Fatigue damage-healing model based on plasticity change for copper film by laser repair
Authors: Liu Xiao-Dong , Shang De-Guang , Sun Guo-Qin
Published: November 2018

A healing method for fatigue damage was investigated by laser shock peening and laser irradiation with excimer laser for polycrystalline copper film. It is found that the sum of the consumed fatigue ductility and the total fatigue ductility for damaged specimen after both laser treatments is equal to the total fatigue ductility for undamaged specimen after both laser treatments. According to the relationship of plasticity, two variables are defined. One is healing variable and the other one is enhancement variable. Based on the relationship of damage variable, healing variable and enhancement variable, a residual fatigue life prediction method is proposed. The results show that the predicted lives by the proposed method agree well with the experimental results.
A chemo-mechanically coupled model for capsule-based self-healing polymer materials
Authors: Tian Fang , Zhong Zheng , Pan Yihui
Published: November 2018

In this paper, a chemo-mechanically coupled model for capsule-based self-healing polymer materials has been proposed within a thermodynamic consistent framework. Elasto-plastic deformation, mechanical deterioration due to plastic damage and recovery resulting from the release of healing agents are all considered. By introducing a variable representing the extent of chemical reaction associated with healing agents, we are able to describe the healing behavior of self-healing materials from chemical kinetics. The Helmholtz free energy function and the evolution equations for the damage and the healing processes are specified. The proposed model offers a novel viewpoint to the establishment of damage-healing models by incorporating chemo-mechanical couplings. Taking the dicyclopentadiene-filled microcapsules and Grubbs' catalyst-embedded self-healing epoxy matrix composite as an example, we discuss the effects of temperature, loading conditions, and initial damage on the evolution of damage-healing and the mechanical performance of self-healing materials.
Maneuver load alleviation for high performance aircraft robust to flight condition variations
Authors: Li Hongkun , Huang Rui , Zhao Yonghui , Hu Haiyan
Published: November 2018

The design of a robust maneuver load alleviation (MLA) system for a high-performance aircraft is studied in this paper. First, the aeroservoelastic (ASE) models of a high-performance military aircraft in climbing maneuver at varying Mach numbers are established. Then, a linear parameter-varying (LPV) model of the ASE systems is constructed and an [Formula: see text] robust controller is designed based on the LPV model. The robust control is realized via a pair of outboard ailerons to alleviate the wing-root bending moments in the climbing maneuvers. To compensate the loss of performance in the load alleviation, a controller based on recurrent neural networks is designed in the flight control. Finally, some numerical simulations are made to testify the performance and robustness of the MLA system.
Telehealth model of care for routine follow up of renal transplant recipients in a tertiary centre: A case study
Authors: Andrew Narissa , Barraclough Katherine A , Long Karrie , Fazio Timothy N , Holt Steve , Kanhutu Kudzai , Hughes Peter D
Published: November 2018

Royal Melbourne Hospital (RMH) performs over 140 kidney transplant operations annually. Kidney transplant recipients require regular medical review, which results in loss of time and costs from travel, particularly for regional patients, and places high demand on the hospital outpatient service.

The RMH renal transplant unit initiated a telehealth service in 2016 to provide cost effective, patient-centred clinical care for regional patients. To date, 263 clinical reviews have been conducted via telehealth, potentially saving 203,202 kilometres in travel distance; 2771 hours in car travel time; an estimated AUD $31,048 in petrol savings and 51 tonnes CO2 equivalents of greenhouse gas emissions.

Lessons learnt have included the importance of using technology that allows patients to access telehealth from their place of choice. The option of a joint consultation with local healthcare providers has facilitated the development of extended care networks for our patients. Incorporation of telehealth into our outpatient system has been achieved with the existing nephrology workforce, making it a sustainable long-term review option.

Our renal transplant telehealth outpatient clinic has been a successful change in the way we provide care to regional patients. Formal comparison of clinical outcomes and the patient experience of telehealth versus in person reviews are underway.