bluuebunny/crossref_metadata_2025 huggingface dataset:
Characterization of Insulin Mucoadhesive Buccal Films: Spectroscopic Analysis and In Vivo Evaluation
Authors: Diab Maram , Sallam Al-Sayed , Hamdan Imad , Mansour Randa , Hussain Rohanah , Siligardi Giuliano , Qinna Nidal , Khalil Enam
Published: January 2021

Insulin mucoadhesive buccal films (MBF) are a noninvasive insulin delivery system that offers an advantageous alternative route of administration to subcutaneous injection. One major concern in the formulation of insulin MBF is the preservation of an insulin secondary structure in the presence of the other film components. Buccal films were formulated using chitosan, glycerin, and L-arginine. The MBF-forming solutions (MBF-FS) and the films (MBF) were examined for their chemical and structural stability and for their in vivo activity. Enzyme-Linked Immunosorbent Assay (ELISA) of the insulin-loaded MBF showed that each individualized unit dose was at least loaded with 80% of the insulin theoretical dose. Results of Synchrotron Radiation Circular Dichroism (SRCD) measurements revealed that MBF-FS retained the α-helices and β–sheets conformations of insulin. Fourier transform infrared (FTIR)-microspectroscopy (FTIR-MS) examination of insulin MBF revealed the protective action of L-arginine on insulin structure by interacting with chitosan and minimizing the formation of an unordered structure and β-strand. A blood glucose-lowering effect of insulin MBF was observed in comparison with subcutaneous (S.C) injection using a rat model. As a result; chitosan-based MBFs were formulated and characterized using SRCD and FTIR-MS techniques. Furthermore, the results of in vivo testing suggested the MBFs as a promising delivery system for insulin.
Stereoselective Synthesis of Chiral α-SCF3-β-Ketoesters Featuring a Quaternary Stereocenter
Authors: Boselli Monica Fiorenza , Faverio Chiara , Massolo Elisabetta , Raimondi Laura , Puglisi Alessandra , Benaglia Maurizio
Published: January 2021

The development of new and efficient methods, reagents, and catalysts for the introduction of fluorine atoms or fluorinated moieties in molecular scaffolds has become a topic of paramount importance in organic synthesis. In this framework, the incorporation of the SCF3 group into organic molecule has often led to beneficial effects on the drug’s metabolic stability and bioavailability. Here we report our studies aimed to the stereoselective synthesis of chiral α-SCF3-β−ketoesters featuring a tetrasubstituted stereocenter. The use of a chiral auxiliary was crucial to synthesize enantiopure enamines that were reacted with N-trifluoromethylthio saccharin or phthalimide, to afford enantioenriched α-SCF3-tetrasubstitued β-keto esters. By using a readily available, inexpensive chiral diamine, such as trans-1,2-diaminocyclohexane, the fluorinated products could be obtained in modest to good yields, and, after the removal of the chiral auxiliary, α-substituted- α trifluoromethylthio-β−ketoesters were isolated with high enantioselectivity (up to 91% ee).
Comparative Analysis of Neurotoxicity of Six Phthalates in Zebrafish Embryos
Authors: Tran Cong , Do Trinh , Kim Ki-Tae
Published: January 2021

The effects and underlying mechanisms of phthalates on neurotoxicity remain unclear as compared with the potentials of these substances as endocrine disruptors. The locomotor activities of zebrafish embryos were investigated upon exposure to six phthalates: dimethyl phthalate (DMP), diethyl phthalate (DEP), benzyl butyl phthalate (BBzP), di-2-ethylhexyl phthalate (DEHP), di-n-octyl phthalate (DnOP), and diisononyl phthalate (DiNP). Moreover, changes in fluorescence intensity in the green fluorescent protein (GFP) transgenic (Tg) lines Tg(HuC:eGFP), Tg(sox10:eGFP), and Tg(mbp:GFP) were measured after exposure to six phthalates, and changes in the expression profiles of genes involved in the cholinergic (ache) and dopaminergic systems (dat, th, and drd1b) were assessed. Exposure to BBzP, DEHP, and DiNP affected larval behaviors, whereas exposure to DMP, DEP, and DnOP revealed no alterations. A reduced expression of Tg(HuC:eGFP) was observed upon exposure to BBzP, DEHP, and DiNP. The expression of Tg(sox10:eGFP) and Tg(mbp:GFP) was reduced only in response to BBzP and DiNP, respectively. Further, exposure to DiNP upregulated ache and drd1b. The upregulation of ache and downregulation of drd1b was observed in DEHP-exposed groups. Exposure to BBzP suppressed th expression. These observations indicate that exposure to phthalates impaired embryogenesis of the neurological system and neurochemicals in zebrafish embryos, although the detailed mechanisms varied among the individual phthalates. Further mechanistic studies are needed to better understand the causality between phthalate exposure and neurotoxicity.
Management of Herpesvirus Infections in Hematopoietic Cell Transplant Recipients
Authors: Styczynski Jan
Published: January 2021

Following primary infection, herpesviruses establish latency in infected individuals in the host cells and may reactivate upon external stimuli and during periods of immunosuppression. The objective of this paper was to the present current strategies on preventive and therapeutic management of infections with herpesviruses in recipients of hematopoietic cell transplantation. Strategies of antiviral management include prophylaxis, pre-emptive treatment and targeted treatment. Empirical therapy is not used in antiviral strategies. Prophylaxis can be done at universal (preventive strategy) and specific level. Universal prophylaxis includes non-pharmacologic methods of prevention of infection or reactivation. Risk-adapted specific prophylaxis includes use of specific antivirals or cellular therapy or other specific methods in order to prevent specific infection, in high-risk groups. Pre-emptive therapy means use of therapeutic approaches in asymptomatic infection, detected by a screening assay. Targeted therapy is used in established specific viral end-organ infections. The following sections of the paper refer to prophylaxis and treatment strategies, respectively, against CMV, EBV, HSV, VZV, HHV-6, HHV-7, and HHV-8 after allogeneic hematopoietic cell transplantation.
Kajian Konsep Zero Complaint Untuk Meningkatkan Minat Beli Ulang pada Program Studi di Universitas Semarang
Authors: DC Kuswardani , TE Yani , Nurhidayati Nurhidayati
Published: January 2021

This study aims to contribute to the understanding of increasing interest in repurchasing the University of Semarang Higher Education services. The variables tested to increase the Repurchase Interest directly are Switching Cost and Perceived Quality. The indirect variable to increase repurchase interest is student satisfaction through Perceived Quality and Service Recovery. The population is all students using USM Higher Education services as many as 25,302 active students, while a sample of 100 respondents using purposive sampling technique. The analytical tool used is Structural Equation Medelling (SEM) with Partial Least Square (PLS) program applications, namely smartPLS.3.0. The results of hypothesis testing indicate that Hypothesis 1 is rejected, while the other hypotheses are supported. Switching Cost has no significant effect on Repurchase Interest. Perceived Quality and Service Recovery is not directly influential on Repurchase Interest, mediated by Student Satisfaction. Student Satisfaction and Service Recovery have a direct effect on Repurchase Interest.
Mechanical, physiological and perceptual responses to different rest interval conditions during consecutive sets of the high-pull exercise
Authors: Sabido Rafael , Hernández Jose Luis
Published: January 2021

Olympic weightlifting movements and their derivates are commonly used within resistance training sessions. The aim of the present study was to assess the influence of different rest intervals (RI) over five sets of the high-pull (HP) on power output performance, lactate concentration [La] and rating of perceived exertion (RPE) responses in trained subjects. Eleven well-trained males attended four testing sessions. The first session consisted of 1 repetition maximum (1RM) assessment. The next three sessions consisted of the same protocol (5 sets x 6 repetitions at 80% 1RM in the HP) but differing in the RI between sets used (1, 2 and 3 min). No significant power output decreases over the five sets in any RI condition. [La] did not significantly differ between RI conditions. The 1 min RI condition led to greater RPE values (6.5 ± 1.8) than both 2 (5.4 ± 1.6) and 3 min RI (5.0 ± 1.8). The present study shows that short RIs (i.e., 1 min) can be used by strength coaches to design more time-efficient sessions. The use of RPE during power training sessions should be considered as a sensitive tool to quantify training intensity.
Health Care Services in Theni District - A Survey
Authors: Moni Sudalai
Published: January 2021

Theni District was carved out of erstwhile composite Madurai district on 01 January 1997 and ranked 28th in terms of the highest population in Tamil Nadu (around 12 ½ lakhs population). For providing necessary Health Care Services and facilities, the task was entrusted to the Public Health and Family Welfare Department. This establishment takes care of - primary health centers, child health services, maintains environmental sanitation and other vital services. Discussed in this paper certain key components such as Health Service Organization at the District level, Medical Department, Hospitals, Dispensaries, services rendered by organization and individuals, functions of primary health centers, family welfare programs, besides facilities in government hospitals, health checkup programs, counseling, and testing centers and other Health Care Services. The study indicates the necessity to enhance not only the quality of service but also to make it more accessible to the rural and tribal population of the Theni District in Tamil Nadu.
Social Implications of Covid-19 Pandemic: A Brief Analysis
Authors: Riswan M
Published: January 2021

The occurrence of Coronavirus disease (Covid-19) has become a serious worldwide health hazard. This newly invented virus or respiratory illness has affected 216 countries so far. This pandemic has caused economic, political, psychological, and cultural impacts across countries, especially among middle-class, lower-class, poor migrants who have been suffered a lot due to this pandemic worldwide. All affected countries are now battling against this tragedy and inventing proper medicine to overcome this very solemn health calamity from the world. Thus, this paper aimed to explore the social implications which occurred due to Covid-19 widespread globally. This article is an initial attempt to study and examine numerous social impacts of Covid-19 and generally interpret the ways how people are adjusting their social life during a lockdown scenario everywhere. Without previous literature contribution, this study intends to input knowledge to the existing fields. It found that people associated with the concept of social distance, lockdown, self-isolation or quarantine, sanitation, etc. In this situation, most of the communities in the world are now distorted, and it has been found that social interaction and social network were disrupted, source of income and job were dislocated, cultural practices and religious institutions are dysfunctional, and people lose their lives daily and affected seriously across global. The study will provide basic facts on social implications of Coronavirus prevalence to use as key ideas for future studies.
Prevalence of Work-Related Musculoskeletal Disorders (WMSD’s) among Bank Employees of Patiala (Preliminary Study)
Authors: Kaur Ramanjit , Pal Nat Ajay
Published: January 2021

The purpose of this study is to examine bank employees of Government and Private sector banks for the prevalence of Work-Related Musculoskeletal Disorders (WMSD’s). For this purpose, a sample group of 30 bankers age 25-35 years were examined with the help of the Standardized Nordic Questionnaire. Statistical tools were used to evaluate the responses from the respondents. Results-56.66% of respondents reported having neck problems, 33.33% Suffers from low backrelated problems, and 20% were suffering from shoulder related problems. The study shows the high prevalence of WMSD’s in bank employees.
ANÁLISIS FACTORIAL CONFIRMATORIO DEL CUESTIONARIO DE SALUD GENERAL GHQ-12, EN ODONTÓLOGOS PERUANOS.
Authors: BECERRA-CANALES BLADIMIR , HERNÁNDEZ-LÓPEZ MIGUEL ÁNGEL , YBASETA-MEDINA JORGE
Published: January 2021

Objetivo: Explorar las propiedades psicométricas de medida del Cuestionario de Salud General GHQ-12, en una muestra de odontólogos peruanos. Métodos: Estudio de tipo instrumental, participaron 260 odontólogos de la región de Ica-Perú, seleccionados por muestreo no probabilístico por disposición. Se realizó análisis de variabilidad y correlación de los ítems, análisis factorial exploratorio (AFE) y para validar la estructura interna del cuestionario el análisis factorial confirmatorio (AFC), que incluyó el método de estimación de máxima verosimilitud robusta; finalmente, evaluamos la confiabilidad del instrumento. Resultados: Los hallazgos confirman índices de variabilidad de los ítems de 0,30 a 0,71; con valores de correlación ítem-total de 0,48 hasta 0,79; el AFC, en base a dos modelos (unidimensional y bidimensional), propuestos por la literatura, mostró que los índices de bondad de ajuste fueron aceptables en el modelo de dos factores. La consistencia interna global mostró un índice satisfactorio (α=0,88); así como, la dimensión disforia general (α=0,85) y disfunción social (α=0,77). Conclusiones: El Cuestionario de Salud General GHQ-12, presenta propiedades métricas aceptables; por lo tanto, puede ser usado en futuras investigaciones y estudios de validación.
Lazer e Pandemia
Authors: Versiani Isabela Veloso Lopes
Published: January 2021

A crise instaurada pela pandemia de coronavírus expõe outras tantas crises e desigualdades em nossa sociedade, que são agravadas pelo modelo de desenvolvimento hegemônico pautado no neoliberalismo. A partir do diálogo com diferentes autores, este ensaio propõe reflexões sobre a temática “Lazer e Pandemia” em articulação com o campo do desenvolvimento e seus desdobramentos no contexto social. Apresenta, como alternativa ao modelo vigente, a aproximação com novas racionalidades e subjetividades que têm no princípio do “comum” um horizonte de potencialidades para a ação e superação dos muitos desafios pela frente. Tais reflexões podem contribuir para pensarmos novos caminhos para e pelo lazer no cotidiano, especialmente quanto ao seu entendimento como uma necessidade fundamental, ao seu potencial político e as suas possibilidades em direção a uma maior emancipação humana.
Chandra Gayatri And Mind : Perspective from Indian Scriptures
Authors: Tandon Neeti
Published: January 2021

Gayatri mantra is one of the most sacred chants to be found in Hindu lore, where an entire philosophy of Indian culture is compressed into these few syllables. Gayatri is the considered as supreme source with infinite divine forces. One of them is ‘Chandra Gayatri’. Chandra (moon) has a strong relation in Indian Scripture. The aim of this perspective is to understand the importance of Chandra Gayatri Mantra in Vedic texts for reaching mental peace and stability.
Human Perception on the Effects of Dust Storm on the Health of Residents’ of Damaturu Metropolis, Yobe State
Authors: Jimme M. A. , Disa A. L. , Ngamdu M. B.
Published: January 2021

Dust storms are among nature’s most violent and unpredictable phenomena. High winds lift dirt or sand particles into the air, unleashing a turbulent, suffocating cloud that reduces visibility to almost nothing in a matter of seconds and cause property damage, injuries, and deaths. Damaturu Metropolis has been experiencing dust storm most frequently more especially during the onset of the rainy season. The study examined the human perception on the effects of dust storm on the health of residents’ of Damaturu metropolis with the aim of identifying and examining the causes, frequency, effects of dust storm on human health and socio-economic life of resident and their coping strategies. A total of one hundred (100) copies of interview schedules were administered to residents of Damaturu metropolis. The result indicated that desertification and deforestation are the main cause of dust storm and the frequency of its occurrence is more often and it occurs most frequently in the second quarter of the year at the onset of the rainy season. Its duration of occurrence ranges from thirty minutes to an hour, although sometimes it varies. The identified health effects associated with dust storms include asthma, allergic reaction, injury and Road Traffic Accident (R.T.A). The socio-economic and livelihood of the community is equally affected during the dust storm episodes. The coping mechanisms adopted by residents during the dust storm, includes closing doors and windows and using face masks. The study recommended that residents should remain indoors, wear face masks, plant trees and cover crops, among others.
Ductility and Seismic Suitability of Locally Sourced High Yield Rebars in Benin City
Authors: Nwankwo E. , Attama E.
Published: January 2021

Ductility is the ability of a system to sustain large deformations beyond its yield point without breaking or failing. Eurocode 8 makes allowance for receipt of seismic forces using the damping capacity of ductile members. This allows for the absorption of energy and helps increase the amount of energy absorbed by ductile structures before failure. This paper investigates the maximum ductility locally sourced steel rebars in Benin City structure can sustain without damage by establishing parameters that influence ductility. Tensile tests were conducted for rebar sizes of 10 mm, 12 mm, and 16 mm diameters, which were sourced from three different vendors within Benin City, Nigeria. The strain-hardening ratio Stu/Sty, i.e. the ratio of tensile strength Stu to yield strength Sty, and the elongation at maximum tensile force Agt were investigated in order to determine plastic deformation capacity and the degree of ductility of these rebars. A numerical model – the modified Ramberg- Osgood and Rasmussen equations – was modified in order to predict the experimentally obtained ductility parameters of these locally sourced rebars. The model collaborates well with experiments and could be used to establish ductility parameters of local rebars. Also, ductility test results showed that strain hardening ratios and elongation were relatively low (Recommended strain hardening ratio of rebar for seismic design is 1.15) and this could result in reinforced concrete structures made with these rebar exhibiting moderate ductility, i.e. a moderate plastic deformation capacity which might not have sufficient energy absorbing capacity in events of large earthquakes.
Assessment of Water Quality of Okomu Wetland Using Water Quality Index
Authors: Ehiorobo S. I. , Ogbeibu A. E.
Published: January 2021

The water quality of the Okomu Wetland was evaluated using the Water Quality Index (WQI) technique which provides a number that expresses overall water quality of a water body or water sample at a particular time. Sampling of physicochemical parameters spanned two years covering the wet and dry seasons and the water quality data were obtained from 10 sampling locations; Ponds 36, 52, 54, 61, 64, 90, 94, Arhakhuan Stream, Okomu River (Agekpukpu) and Okomu River (Iron bridge) all within the Okomu National Park. Parameters such as Total Dissolved Solids (TDS), Turbidity, pH, Electrical conductivity (EC), Chlorine (Cl), Nitrate (NO3), Sulphate (SO4), Sodium (Na), Magnesium (Mg), (Iron) Fe, Chromium (Cr), Zinc (Zn), Copper (Cu), Manganese (Mn), Lead (Pb), and Nikel (Ni) were used to compute WQI and the values obtained for the wetland ranged between 34.36 and 167.28. The Index shows that pond 36, 52 and 54 are unfit for drinking with values between 103.86 and 167.28; ponds 61 and 64 are of the very poor quality category with WQI values of 95.19 and 92.44 respectively, Pond 90, pond 94, Arhakhuan Stream and Okomu River (Agekpukpu) are of poor quality and WQI values between and 53.58 and 73.15. Whereas, the Okomu River (Iron bridge) is within the good water quality (34.36) category. The Okomu River by Iron bridge is of good quality rating while other sampled points were of poor, very poor or unfit for drinking though these water bodies are mostly free from anthropogenic activities because of the conservative status of the study area. A major source of pollution within the wetland is surface runoff. The water quality of the wetland may not be suitable for man’s consumption especially pond water which are majorly impacted by runoff, yet very important for the survival and sustenance of the forest animals and plants. The water quality index (WQI) interprets physicochemical characteristics of water by providing a value which expresses the overall water quality and thus, reveals possible pollution problems of a water body. It turns complex water quality data into information that is easily understandable and usable by scientists, researchers and the general public.
Modelling and Forecasting of Ikpoba River Discharge in the Niger Delta Region using Adaptive Neuro-Fuzzy Inference System (ANFIS)
Authors: Egbiki S. , Ehiorobo J. O. , Izinyon O. C.
Published: January 2021

In this study, the discharge of Ikpoba River was modelled and forecasted using adaptive neuro-fuzzy inference system (ANFIS). The river daily discharge, temperature and precipitation data sets from year 1991 to 1995 were used. In applying the ANFIS, five models stages; model-1, model-2, model-3, model-4 and model-5 were created using MATLAB. Model-1 to 4 were created using only the river discharge data, while model-5 was created by incorporating temperature and precipitation to cater for the effect of climate change into model-4. Five performance evaluation criteria, coefficient of correlation (R), coefficient of determination (R2), mean square error (MSE), modelling efficiency (E) and index of agreement (IOA) were used for comparative analysis. The results showed that though Model 1 to 4 were able to predict the river discharge accurately, model-5 (when the effect of climate change was incorporated) performed better than the other four models with only discharge data. The training phase in model-5 showed an over-estimation of 0.043% of the observed target output sets while an over-estimation of 0.044% was observed in the testing phase. These are within acceptable error tolerance of +/-10% for data validation. This information is useful for integrated water resources planning and management.
BACKPACKS – LUMBAGO AFFECT ADOLESCENT AND CHILDREN: A REVIEW
Authors: Qamar Mehek , Aamir Khan Amna , Nadeem Muhammad , us Saba Navaid
Published: January 2021

OBJECTIVE
Occurrence of Low Back Pain (LBP) at an early age, the associated causal
factors and resulting consequences in adulthood have been an area of interest
for many researchers around the globe. A systematic review in accordance
with PRISMA was performed to explore the prevalence of LBP and significant
role of carrying heavy backpacks as a risk factor among various others for
developing mechanical low back pain among school going children.
An electronic search of databases from 2000 to 2013 was carried out. The
selected articles reported LBP due to mechanical loads in children and
adolescents aged 9-18 years as main outcome. Our analysis was conducted on
prevalence rates and associated risk factors.
The results of the review revealed mostly the outcome measure based upon
prevalence, risk factors of mechanical LBP and the association with backpack.
Adolescent girls and children reported higher prevalence. The review reported
the use of heavy backpack as dominant risk factor followed by psychological
factors and physical inactivity. Only 1 study outlined incorrect posture and
structural anomalies as the resulting cause.
A positive correlation is found between heavy backpack and childhood LBP.
The review exhibits a higher prevalence with increasing age.
FREQUENCY AND TYPE OF FRACTURES ENTERING THE EMERGENCY UNITS OF ORTHOPEDIC HOSPITALS
Authors: Rekha Pawan , Kumari Sheena , Aamir Khan Amna
Published: January 2021

BACKGROUND
Trauma is globally encountered in the emergency department on regular
intervals placing a burden on the economy through an increase in the mortality
and morbidity. Multiple types of fractures have been notified leading from
moderate to severe disability.
The aim of the study is to assess different types of fracture entering the emergency
department, the risk of these fractures and also to find the association
between genders.
A cross sectional survey was conducted on 450 participants in different
Emergency Departments of tertiary care units of Karachi.
It has been observed that fracture cases are increasing in emergencies in
Karachi. Road Traffic Injuries (RTA) with 41.6% is the most dominant cause of
fracture whereas fall or slip injuries and brawl/fight show 22.2% and 14.7%
respectively. Generally, alcohol and cigarette smoking has adverse effect yet
91.6% population revealed no relationship. Regional distribution of fracture
shows lower limb fracture with 40.9% as most commonly occurring fractures
where male percentages is higher than females. The selected population
presented no idea about BMD and Vitamin D test which causes fractures in old
age commonly.
LEVEL OF SATISFACTION OF PHYSIOTHERAPISTS WITH REGARDS TO THEIR PROFESSION
Authors: Usman Rabia , Nafees Fariha , Imran Farooqui Sumaira , Mujahid Faruq Nabiha
Published: January 2021

The aim of this study was to investigate the level of satisfaction among
physiotherapist with regards to their profession
A cross sectional survey was conducted.
The data was collected from 450 physical therapists with recognized degrees of
BPT, PPDPT, and Masters in Physical Therapy. Data was collected from 5 tertiary
care hospitals, 6 clinics and privately practicing Physiotherapists in Karachi.
The results shows that 70% physiotherapist somewhat satisfied with their general
working conditions. When assessed the barriers face during the job with respect
to gender it was observed that neutral responses were reported.
The finding shows that the physiotherapists are moderately satisfied with th
FREQUENCY OF WORK RELATED LOW BACK PAIN AMONG PHYSICAL THERAPISTS
Authors: Javed Saima , Jawaid Sultan Anum , Khan M. Usman , Rahim Maria
Published: January 2021

To find out the frequency of work, related to Low Back Pain (LBP) among
physical therapist of tertiary care hospital of Karachi. To analyze the effects of
physical activity level, sub-specialty areas and Body Mass Index (BMI) on Work
Related Low Back Pain (WRLBP) as well.
A cross-sectional survey was conducted with non-probability convenience
sampling technique was used.
The study included 265 Physical Therapist working in Tertiary Care Hospitals of
Karachi.
Data was collected throughpre-tested, structured and self-administered
questionnaire and then,wasanalyzed on SPSS version 17.
This study reported that prevalence of WRLBP was 66.4%. The rate was higher in
femalephysiotherapist, that is, 42.6%. Data revealed that, 69% of respondents
experienced WRLBP within 2 years of their practices. Moreover, the manual
therapy was found to be the most common cause for WRLBP. No significant
association was found between BMIand physical activitylevel of physical
therapist, but interestingly, it was found that sub-specialty area of work was
correlated with WRLBP.
The rate of WRLBP has been found to be high in physical therapists due to their
profession. It is therefore, required to build up an effective ergonomic strategy,
strengthen training for prevention at undergraduate level in order to reduce
and prevent WRLBP.
WORKSTATION FOR UNIVERSITY FACULTY – AN ERGONOMIC VIEW
Authors: Noor Nizam Ghazala
Published: January 2021

Ergonomics deals with work performance, emphasizing on worker safety and productivity. It deals with the scientific study of
human capabilities and limitations in relation to work demands. Ergonomics is a crucial issue nowadays because with the
advancement in technology, all tasks in most organizations, especially universities, are completed in a sedentary position and
on the computer. If daily tasks are not carried out properly without considering posture and duration, there will be slow development
of injuries. A person starts making adjustment to body instead of work environment, which further predisposes to
injuries. When ergonomically-designed workstations are not utilized, it leads to Repetitive Strain Injuries (RSI) and Musculoskeletal
disorders (MSD).
Applying ergonomics at any organization helps to make the workplace comfortable and efficient for the worker, hence, it is
important to introduce ergonomic workstations at universities. Usually, most individuals are not concerned about the posture
in which they sit and work. Either, they are unaware about good posture habits or may not consider it a health-risk. When pain
is initially felt, it is ignored until severe symptoms begin to surface. Prolonged periods of work with the head or trunk bent puts
stress on them; hence, complaints arise over the time spend. Working with unsupported raised arm predisposes to shoulder
strain. Furthermore, factors that contribute to ergonomic injuries are: sitting in awkward postures by tilting head down or
forward, leaning forward, keeping wrist or elbow on hard surface. Chair height does not correspond with their popliteal height
- either it is low or high. Also, not using a document holder when working with computers or working continuously without
intervals - all these behaviors play a role in developing or accelerating the problems.
T4 SYNDROME: THE PAIN IN NECK THAT IS OFTEN MISDIAGNOSED
Authors: Shafqat Sadaf
Published: January 2021

It has been ascertained that musculoskeletal issues arising from the upper thoracic spine are often incorrectly diagnosed
as cervical in nature, by both the therapists and the medical professionals equally. This may be due to the reason that the
lower cervical and upper thoracic vertebrae are closely linked with regards to cervical movements, predominantly, flexion,
and extension. Symptoms from the upper thoracic spine can also bring up pain in the arm and forearm, thus, mimic a heart
attack1.
One such condition of upper thoracic spine is of T4 vertebra - the T4 syndrome. In 1994, Evans P, discussed the basic science
behind the genesis of T4 syndrome and argued that, the term upper thoracic disorder might be a more accurate term, in view
of the fact that, the condition generally ranges between T1 to T72. However, it is generally referred to as T4 or T3 syndrome3. If
we examine the vertebral column, the compressive load at T1 is about 9% of body weight, increasing to 33% at T8 and 47% at
T124. In between each one of these vertebrae, lie the facet joints and discs, which help in maintaining the weight and directing
the movement among the individual vertebrae. When either of these joints gets injured, damage in turn can be imposed on
the nerves
CASE STUDY: WEIGHT LOSS CAUSES IMPROVEMENT IN METABOLIC SYNDROME AND COST EFFECTIVE
Authors: Sarfraz Muhammad , Naz Erum , Shamsi Arham , Rizvi Syeda Amool Sakeena , Ilyas Roomi
Published: January 2021

A case report study conducted in a tertiary care hospital to determine the
effectiveness of supervised exercise diet plan along with behavioral therapy to
reduce weight in the metabolic syndrome. A 54 years old obese male was
selected to conduct the study that suffering from diabetes for last 10 years,
hypertensive previous 13 years, knee osteoarthritis previous 8 years back and
also has complaint of dyspnea as a result facing severe problems in his ADL. He
was on 8 different medications when he visited a Physiotherapy OPD in a tertiary
care hospital by his consultant to secure his health status. He was than enrolled
in fitness program to reduce weight under supervision of a physical therapist.
According to his lab reports he was highly on health risk and was going in severe
depression due to the difficulty facing in his daily life. The out measures of our
study was Visual Analogue scale, Exercise and diet plan with counseling
sessions, after 16 weeks supervised exercise diet plan and counseling sessions
we observe a marked improvement in glucose tolerance, exercise tolerance,
lipid profile and hypertension. The patient was following exercise plan for
5days/week and diet plan throughout the month with a single counseling
session in a week with marked reduction in medications. Our study concludes
that the medically supervised weight-loss program facilitates is safe and
effective in weight
The cultivation of Argyranthemum frutescens L. in the "Alexandru Ciubotaru" National botanical garden (Institute) and prospects for its development
Authors: Voineac I. V.
Published: January 2021

Argyranthemum frutescens (L.) Sch.Bip. (clade Magnoliophyta, class Magnoliopsida, order Asterales, family Asteraceae, genus Argyranthemum Webb ex Sch. Bip) is commonly named Paris daisy, marguerite or marguerite daisy. The species was formerly considered part of the genus Chrysanthemum, but now it is placed in an independent genus – Argyranthemum, which includes 23 species. The research was carried out in the greenhouse and on the experimental site of the Floriculture Laboratory of the “Alexandru Ciubotaru” National Botanical Garden (Institute). The article presents the results of studying the ontogenetic stages and biological characteristics of various cultivars of Argyranthemum frutescens L. Eight cultivars of Argyranthemum frutescens L. served as research subjects (White Swan, AngelicTMLemon, AngelicTMMagentа, Neptun, Pink Delight, Perfection pink, Burgundy, Giant Pink ). In accordance with the methodology, the study on cultivars was carried out taking into account the shape of the bush, the density of the foliage, the height and habit of the bush, the size and colour of the leaves, the shape, size, type and colour of inflorescences. The regenerative abilities and the capacity to produce shoots of marguerite daisy were studied. The optimal time for propagation, the length and intensity of the flowering phase of the introduced cultivars have been determined. The optimal conditions for their successful propagation and cultivation in Moldova have been established. On the basis of observations, the economic value and the best uses of marguerite daisy in landscape design have been determined. According to the results of the study on cultivars, their characteristics have been determined. It has been found that the main stages of ontogenesis in Argyranthemum frutescens L. are not clearly defined. The onset of a certain stage of development and its duration depends on climatic conditions. Some agricultural techniques for growing Argyranthemum frutescens L. under the given soil and climatic conditions have been developed.
PENGARUH PERMAINAN TERHADAP KEMAMPUAN PASSING BAWAH BOLAVOLI PADA PESERTA DIDIK KELAS VIII MTsN 6 JOMBANG
Authors: Arnaz Arnaz
Published: January 2021

Tujuan Penelitian ini adalah untuk mengetahui  Pengaruh Permainan Terhadap Kemampuan Passing Bawah Bolavoli pada Peserta Didik Kelas VIII-B MTsN 6 Jombang. Jenis penelitian kuantitatif menggunakan model One group Pretest- Posttest Design. Sampel seluruh peserta didik kelas VIII-B MTsN 6 Jombang. Penilaian tes ini yang dinilai yaitu kemampuan Passing Bawah. Berdasarkan hasil penelitian, bahwa pada hasil penelitian ini diperoleh perhitungan hasil proses pada tabel Paired Samples T-Test diperoleh Sig (2-tailed) sebesar 0,000. Hal ini berarti nilai sig 0,000 < 0,05, maka H0 ditolak. Berdasarkan data tersebut dapat disimpulkan bahwa ada pengaruh permainan terhadap kemampuan passing bawah pada peserta didik kelas VIII-B MTsN 6 Jombang. Sesuai dengan deskriftif data dan pembahasan, maka dapat disimpulkan bahwa terdapat pengaruh yang signifikan antara permainan terhadap kemampuan passing bawah pada peserta didik kelas VIII-B MTsN 6 Jombang. maka peneliti menyarankan sebagai berikut: (1) Dengan adanya penelitian ini diharapkan dapat menjadi salah satu acuan dalam pembelajaran PJOK khususnya passing bawah dalam pembelajaran bola voli agar lebih kreatif dan inovatif. (2) Untuk penyempurnaan hasil penelitian yang lebih baik maka perlu dilakukan penelitian lagi. (3) Untuk mendapatkan hasil yang lebih baik, perlu dilakukan penelitian dengan populasi yang lebih luas terhadap sampel yang diperketat.
PENGGUNAAN MEDIA PIRING PLASTIK TERHADAP HASIL BELAJAR LEMPAR CAKRAM PADA SISWA KELAS VII A SMP NEGERI 2 SUKODONO SIDOARJO
Authors: Frederika Saputri Sabar  , Moh. Hanafi
Published: January 2021

Pendidikan jasmani dapat diartikan sebagai suatu proses pendidikan melalui kegiatan jasmani yang dirancang untuk meningkatkan kesegaran jasmani, keterampilan, pengetahuan dan sikap sehat, sportivitas dan sikap aktif. Tujuan yang ingin dicapai dalam penelitian ini adalah untuk mengetahui sejauh mana media modifikasi plat plastik dapat meningkatkan keefektifan pembelajaran lempar cakram siswa kelas VII A SMPN 2 Sukodono. Rancangan penelitian yang digunakan dalam penelitian ini adalah metode one group pre-post test design dengan subjek 20 siswa. Berdasarkan hasil penelitian penggunaan media piring plastik berpengaruh terhadap hasil belajar lempar cakram pada siswa kelas VII A SMPN 2 Sukodono dibuktikan dari hasil perhitungan statistik menunjukan peningkatan dari hasil pre test dan post test sebesar rata-rata pre test 73,05 dan hasil post test 84,70.
Pengaruh Produk, Testimoni Dan Store Atmosphere Terhadap Minat Beli Ulang Di Kafe Warunk Upnormal Gresik
Authors: Yohanes Dicky Yoeniargo  , Sutama Wisnu Dyatmika
Published: January 2021

Dalam menunjang usaha dalam meningkatkan pembelian pada warunk upnormal di gresik maka perlu dilakukan suatu penelitian mengetahui pengaruh Pengaruh Produk, Testimoni dan Store Atmosphere  secara Terhadap Minat Beli Ulang di kafe Warunk Upnormal Gresik. jumlah ada 105 orang. Hasil penelitian diharapkan dapat digunakan oleh manajemen warunk upnormal dalam upaya meningkatkan pendapatn melalui peningkatan pembelian  knsumen. Hasil pengujian diperoleh hasil bahwa Produk, Testimoni dan Store Atmosphere berpengaruh positif dan signifikan terhadap Minat Beli Ulang di Kafe Warunk Upnormal Gresik.
PENGARUH STORE ATMOSPHERE DAN lN-STORE DlSPLAY TERHADAP lMPULSE BUYlNG Dl MATAHARl DEPARTMENT STORE ClTY OF TOMORROW - SURABAYA
Authors: Nindrasari  , I Ketut Surabaiarta
Published: January 2021

Perkembangan bisnis riteI di lndonesia teIah berkembang dengan sangat cepat termasuk bisnis riteI yang ada di Surabaya. lniIah yang memicu terjadinya persaingan antar bisnis riteI yang juga diaIami oIeh Matahari Department Store City Of Tomorrow Surabaya. Maka Matahari Department Store City Of Tomorrow Surabaya harus memanfaatkan betuI konsumen yang datang dengan membuat mereka meIakukan yang namanya lmpulse Buying.Tujuan peneIitian ini untuk mengetahui pengaruh store atmospheredan in-store dispIay terhadap impuIse buying pada konsumen di Matahari Department Store City Of Tomorrow Surabaya. PeneIitian ini teIah mengambil sampeI sebanyak 110 manusia dengan teknik pengambiIan sampeI yaitu accidentaI sampIing dengan menyebarkan kuesioner.
ANALISIIS FAKTOR – FAKTOR YANG MEMPENGARUHI KINERJA SISTEM INFORMASI AKUNTANSI PADA PT. BINA AREA PERSADA
Authors: Arik Puji Rahmawati  , Taudlikhul Afkar
Published: January 2021

To analyze the factors that influence the performance of accounting information systems is a goal that researchers want to achieve. Retrieval of data by distributing questionnaires to respondents, then analyzing the data that has been obtained and then draw conclusions. The results of respondents' answers by using several tests such as validation tests and so on to support more valid results and the results can be justified. The results show that the Capability of Personnel Techniques, Management Support, User Engagement and User Education and Training affect the performance of the accounting information system
FAKTOR FUNDAMENTAL YANG MEMPENGARUHI HARGA SAHAM PERUSAHAAN BUMN YANG TERDAFTAR DI BEI TAHUN 2016-2018
Authors: Sixma Goodta Rama  , Mohamad Afrizal Miradji
Published: January 2021

The purpose of this study was to determine the influence of fundamental factors on the price of shares on the Indonesia Stock Exchange (IDX). The background of this writing because there are only few companies listed on the IDX and show a decline in the Composite Stock Price Index (CSPI). This study used 39 samples from 13 state own companies (BUMN) with reporting period of 3 years. Data is used secondary data. Research writing method uses quantitative methods, where the analysis of data with classic assumption test, multiple linear regression analysis, and the coefficient of determination. While testing the hypothesis by t test and f test. This study shows the results of hypothesis testing with CTO and ATO significantly influence stock prices. While DAR, ROA, and PER have no significant effect on stock prices. Simultaneously the ratio of CTO, DAR, ATO. ROA, and PER signifacnly influence the stock prices of BUMN companies.
Analisis Perbandingan Kinerja Dalam Proses Pembuatan Laporan Kas Harian Secara Manual Dan Penggunaan Sistem Accurate Pada CV. Rejeki Abadi
Authors: Moses Albertho Girendra  , Taudlikhul Afkar
Published: January 2021

The case study of this research intends to analyze the performance comparison of making daily cash statements manually and using an accurate system on the company CV. Eternal Fortune. Qualitative data is used in this study. The author uses primary and secondary data sources. Based on the results of the analysis and discussion by the author, it states that the performance of the process of making a daily cash statement using accurate can be completed faster and more precisely because it has been integrated while making it manually is very long time because it must be written one by one.
Pengaruh Current Ratio(CR), Return On Equity (ROE), Debt To Equity Ratio (DER)Terhadap Harga Saham (Pada Perusahaan Manufaktur yang Terdaftar di BEI Periode 2015-2018)
Authors: Dhawi Ardy Wibowo  , Moh Afrizal Miradji  , Ulfa Puspa Wanti Widodo
Published: January 2021

Produk adalah sertifikat kepemilikan perusahaan, dan pemegang saham berhak mengklaim pendapatan dan aset perusahaan. Motif penelitian ini adalah untuk mengetahui pengaruh Current Ratio (CR), Return on Equity (ROE), dan Debt to Equity (DER) persentase Indonesia secara bergantian selama 2015-2018. Simak metode kuantitatif yang digunakan, sebuah contoh ditemukan oleh 10 produsen pada 2015-2018. Kumpulan record menggunakan beberapa jejak regresi. pada pendapatan (ROE) dan debt to income ratio (DER) terpengaruh dan pada saat yang sama berdasarkan total share charge dari grup-grup yang terdaftar pada perdagangan saham Indonesia tahun 2015-2018.
Pengaruh Kualitas Produk dan Desain Produk Terhadap Keputusan Pembelian Sepatu Adidas Universitas PGRI Adi Buana Surabaya
Authors: Ichwan Haqqi Muhammad  , Subakir
Published: January 2021

PeneIitian ini diIakukan untuk mengetahui Pengaruh KuaIitas Produk dan Desain Produk terhadap Keputusan PembeIian Sepatu Adidas Universitas PGRI Adi Buana Surabaya PopuIasi yang diteIiti sebanyak 100 responden dengan cara menyebarkan kuisioner dan menggunakan teknik random sampling. Pengujian instrumen data yang digunakan Uji Validitas dan Uji ReIiabilitas. Uji Asumsi kIasik dengan Uji NormaIitas Data, Uji MuItikolinieritas, Uji AutokoreIasi, dan Uji Heteroskedasitas. Analis data Regresi Linear Berganda. Pengujian Hipotesis menggunakan Uji t dan Uji F. HaI tersebut menunjukan bahwa KuaIitas Produk dan Desain Produk berpengaruh terhadap Keputusan PembeIian Sepatu Adidas Universitas PGRI Adi Buana Surabaya.
Pengaruh Likuiditas, Leverage, Profitabilitas Dan Ukuran Perusahaan Pada Kelengkapan Pengungkapan Laporan Keuangan Perusahaan Rokok Yang Terdaftar Di Bursa Efek Indonesia
Authors: Mei Gita Risti Mawarni  , Rina Fariana
Published: January 2021

Maksud peneliti melakukan penelitian ini ialah untuk memahami dan mengkaji apakah ada impresi likuiditas, leverage, profitabilitas, dan ukuran perusahaan terhadap kelengkapan pengungkapan laporan keuangan atas perusahaan rokok yang tertera di BEI tahun 2012-2018. Variabel daIam observasi ini yakni 4 perusahaan rokok. Penjabaran eksplorasi ini menggunakan metode anaIisis regresi Iinier berganda. Didapatkan hasiI uji-t bahwa niIai sig X1 sebanyak 0,646 < 0,05, niIai sig X2 sebanyak 0,40 < 0,05, niIai sig X3 sebanyak 0,000 < 0,05 dan niIai sig X4 sebanyak 0,000 < 0,05. Sedangkan dari uji-F diperoIeh niIai Fhitung sebanyak 39,520 Dengan sig sebanyak 0,000, sehingga 0,000 < 0.05. dari uraian tersebut menunjukan bahwa leverage, profitabiIitas dan ukuran perusahaan berpengaruh signifikan dan Iikuiditas tidak berpengaruh signifikan terhadap kelengkapan pengungkapan Iaporan keuangan baik secara parsiaI dan berpengaruh secara simuItan
Peningkatan Keaktifan dan Motivasi Belajar Mahasiswa melalui Pendekatan Kontekstual
Authors: Purwasih Silviana Maya , Rani Kurnia Putri
Published: January 2021

Penelitian ini bertujuan untuk meningkatkan keaktifan dan motivasi belajar mahasiswa Program Studi Pendidikan Matematika di Universitas PGRI Adibuana pada mata kuliah Matematika Kejuruan melalui pendekatan kontekstual. Penelitian Ini merupakan Penelitian Tindakan Kelas dengan 2 siklus. Teknik pengumpulan data dilakukan melalui observasi, angket, dan dokumentasi, sedangkan teknik analisis data menggunakan reduksi data, penyajian data, dan penarikan kesimpulan. Hasil penelitian ini menunjukkan bahwa pendekatan kontekstual memberikan konstribusi dalam meningkatkan keaktifan dan motivasi belajar mahasiswa pada mata kuliah Matematika kejuruan. Secara klasikal, peningkatan tersebut dapat dilihat dari hasil data presentase angket keaktifan belajar mahasiswa pada siklus I mencapai 64,28%, pada siklus II meningkat sebesar 12,43% menjadi 76,71%, juga melalui presentase keseluruhan indikator motivasi belajar mahasiswa  yang semula pada siklus I sebesar 62,10%, pada siklus kedua meningkat sebesar 13,74% menjadi 75,84%.
PERAMALAN BEBAN LISTRIK JANGKA PENDEK PADA PT. PLN AREA JAWA TIMUR Ã‚â€“ BALI MENGGUNAKAN SUPPORT VECTOR MACHINE
Authors: Trapsilasiwi Rani Kemala
Published: January 2021

Peramalan beban listrik jangka pendek merupakan faktor yang sangat penting dalam perencanaan dan pengoperasian sistem tenaga listrik. Tujuan dari peramalan beban listrik adalah agar permintaan listrik dan penyediaan listrik dapat seimbang. Metode Support Vector Machine (SVM) adalah salah satu metode yang dapat dipakai untuk peramalan beban listrik dikarenakan karakteristik beban listrik sangat fluktuatif dan mempunyai pola non linier. Keakuratan metode SVM dapat diketahui dengan menggunakan MAPE, MAE, MSE, MPE dan R2. Hasil dari kriteria keakuratan menunjukkan bahwa hasil peramalan SVM adalah sangat bagus dengan nilai MAPE dari SVM adalah 3.01 serta nilai R2 dari SVM adalah 91.53%.
Tabel Kontingensi Untuk Mengetahui Hubungan Antara Jenis Penyakit, Jenis Kelamin, Usia, Lama Rawat dan Keadaan Keluar Pasien
Authors: Pramesti Wara
Published: January 2021

Tabel kontingensi dapat digunakan untuk melihat hubungan dua peubah kategorik. Dari tabel kontingensi ini dapat dibuat kesimpulan apakah ada hubungan antara satu variabel dengan variabel lainnya. Data jenis penyakit, jenis kelamin, usia pasien, lama rawat dan keadaan keluar pasien diambil dari rumah sakit Siti Khadijah Sepanjang yang selanjutnya dengan menggunakan uji Chi-Square pada table Kontingensi dapat diketahui hubungan antara jenis penyakit dengan jenis kelamin, jenis penuyakit dengan usia dan jenis penyakit dengan lama rawat serta jenis penyakit dengan keadaan keluar pasien. Hasil analisis menunjukkan bahwa jenis kelamin dan usia pasien rawat inap tidak saling bebas dan keduanya saling berkaitan. Ketergantungan antara jenis penyakit dengan jenis kelamin yang paling signifikan adalah jenis penyakit GE atau diare, gastritis dan diabetes mellitus. ada jenis penyakit tertentu yang tidak signifikan hubungannya dengan usia pasien yaitu untuk jenis penyakit gastritis pada usia remaja, penyakit hypertensi pada usia dewasa, penyakit pneumonia pada usia tua dan lansia, penyakit step pada usia anak Ã‚â€“ anak dan juga penyakit FUO (demam) pada usia dewasa. Untuk hal dependensi yang paling signifikan antara lama rawat dengan keadaan keluar pasien adalah lama rawat lebih dari 2 minggu dan keluar dalam keadaan di rujuk ke rumah sakit lain dan meninggal.