bluuebunny/crossref_metadata_2025 huggingface dataset:
Macro- and micro-morphological characteristics of Kickxia Dumort. and some related taxa in Saudi Arabia
Authors: Masoudi Luluah M Al , Bukhari Najat A , Whibi Mona Al
Published: June 2022

The morphological and anatomical aspects of 13 species belonging to genera Kickxia, Scrophularia, and Plantago of Saudi Arabia reveal that the species of Kickxia and Scrophularia are distinct from Plantago major. The most notable morphological differences are the absence of adventitious roots and the presence of acaulescent stem in the species of Kickxia and Scrophularia and the existence of adventitious roots and the absence of acaulescent stem in P. major. The species of Plantago possessed rose-shaped radical leaves, whereas the rest of the species studied had cauline leaves or both. The species of Kickxia and Scrophularia have pentamerous flowers with bilabiate corollas, whereas, P. major has tetramerous flowers with tubular corollas. The separation of P. major from the rest of the studied species is the most obvious result obtained from the dendrogram, and this result is consistent with some traditional taxonomic studies that placed Kickxia in the Scrophulariaceae species while separating P. major into an independent family Plantaginaceae. The anatomical findings revealed that the upper and lower epidermal cells of the leaves were irregular with undulate walls in all analyzed species, except in P. major, where they were polygonal with straight walls. Only P. major had amphianisocytic paracytic stomata, but eight Kickxia species had anomocytic stomata and K. hastata and K. abhaica, and the two Scrophularia species had anisocytic stomata. Therefore, this study suggests the retention of the Kickxia in Scrophulariaceae s.l. and maintaining Plantago in Plantaginaceae s.s.
Bangladesh J. Plant Taxon. 29(1): 1-11, 2022 (June)
Study of Ethnomedicinal Plants Used by the Local People Of Raipura Upazila of Narsingdi District
Authors: Islam Samia , Uddin Mohammad Zashim
Published: June 2022

An ethnomedicinal investigation was conducted from July 2019 to June 2020 in Raipura Upazila, Narshingdi district. The main aim of this study was to record, integrate and document all the scattered distributions of traditional healthcare knowledge of medicinal plants. Data collection of ethnomedicinal plants were performed through key informant interviews, field interviews, checklist interviews, Plant interviews, semi - structured interviews and group discussion. A total of 87 medicinal species with 114 formularies to treat 69 ailments have been recorded. These species belong to 49 families. Most frequently used plant species are trees (43%) followed by herbs (31%), shrubs (21%) and climbers (5%). Oral consumption is the main mode of treatment in the study area followed by external application. The reported ailments were classified into 15 disease categories. Maximum plant species were reported to treat diarrhoea and dysentery. The highest Factor informant consensus (Fic) value was found in respiratory category (fever, cold, cough, pneumonia).The most cited species for this category are Ocimum sanctum L., Nigella sativa L. and Jasticia adhatoda L. Cardiovascular disease showed second highest Fic value. The most cited plant species for this category are Terminalia arjuna (Roxb. ex D.C.) Wight & Arn., Tamarindus indica L. and Allium sativum L. In this survey, 8 species scored 100% Fl values for different disease categories. These are Aerva sanguinolenta (L.) Blume, Neolamarckia cadamba (Roxb.) Bosser, Tamarindus indica L., Momordica charantia L., Cocos nucifera L., Ocimum sanctum L., Leucus aspera (Willd.) Link. and Jasticia adhatoda L. Therefore, such plant species could be further analyzed for bioactive constituents that can lead to discovery of new and potential drugs. The study also revealed that the medicinal plants and traditional knowledge in Raipura Upazila are in threatened condition due to different disturbances and some suggestions have been recommended for conservation.
Bangladesh J. Plant Taxon. 29(1): 137-156, 2022 (June)
Enumeration of Climbing Angiosperms in and Around Rajshahi City, Bangladesh
Authors: Hasan M Tarikul
Published: June 2022

Abstract not available
Bangladesh J. Plant Taxon. 29(1): 161-165, 2022 (June)
Synthesis of nano-sized magnetic iron oxide by a simple and facile o-precipitation method
Authors: Khanam J , Ahmed MF , Zaman SKM , Sharmin N , Ahmed S
Published: June 2022

Magnetic iron oxide (Fe3O4) in nano form has been synthesized by a simple wet chemical method involving co-precipitation using iron salt and ammonium hydroxide as precipitating agents. Characterization of the synthesized nanoparticles were carried out by using XRD, FTIR, FESEM and VSM techniques. Crystallite sizes determined from XRD data were found to be between 6.8 and 12.6 nm with face center cubic crystal structures. The lattice parameter was determined to be 8.34 Å. FESEM microstructure revealed a spherical like nanoparticles with average particle size of. The saturation magnetization of the synthesized magnetite nanoparticles was measured to be 49.88 emu/gm. The Fe3O4 nanoparticles synthesized by co-precipitation method is considered to be potentiality good magnetic material with diverse applications.

Bangladesh J. Sci. Ind. Res. 57(2), 67-76, 2022
Aloe vera cookies preparation, nutritional aspects, DPPH assay and physicochemical assay
Authors: Zahra N , Saeed MK , Nawaz S , Gulzar E
Published: June 2022

Aloe vera has been widely used for various therapeutic purposes over the millennia. It is becoming increasingly popular due to its antiviral and antibacterial qualities. For many years, aloe vera has been employed in biomedical research. It's a fantastic way to boost the nutritional value of any food product. This research aims to expand on the nutritional value of cookies by including Aloe vera gel. It would focus on the substance's biological and pharmacological characteristics. The nutritional quality of aloe vera cookies was evaluated after being manufactured with all-natural, chemical-free ingredients. The primary objective was to investigate its functional properties, sensory characteristics, and quality characterization. Quality control was performed on aloe vera cookies, and the results were discussed. The process is quick and straightforward, and it comes at a reasonable cost that boosts nutrient content, but it can also be utilized as a part of a well-balanced diet. Because of its beneficial characteristics, aloe vera-based cookies could be particularly beneficial for most vulnerable groups in underdeveloped countries. The cookies are safe to eat daily as a snack food.
Bangladesh J. Sci. Ind. Res. 57(2), 117-122, 2022
Design and Development of Clarithromycin Floating Pellets Using Sodium Alginate and HPMC
Authors: Bhuiya Md Abdul Motaleb , Mazumder Kishor , Dewan Irin , Mamun Md Elias Al
Published: June 2022

The purpose of our study was to achieve the gastro-retentive delivery of Clarithromycin by producing floating pellets to get a better therapeutic effect against gastrointestinal ulcers mostly caused by Hedyotis pylori. Thereby Clarithromycin floating pellets were prepared by utilizing the blending of polymers such as Sodium (Na) Alginate and Hydroxy Propyl Methyl Cellulose (HPMCK4M & HPMC K100LV). The HPMC-alginate blend containing Clarithromycin produced a hydrogel bead that was able to show buoyancy in the simulated gastric fluid. The pellets showed more than 8 hours of buoyancy depending on their polymeric ratio. In addition to the buoyancy test, several other tests like floating time (upto 12 hrs with increasing Na-Alginate), contraction ratio, particle size analysis, were performed that showed the development of acceptable floating pellets. Furthermore, SEM was performed on the prepared Clarithromycin pellet to assess their morphological characteristics. Clarithromycin floating pellets with 1.5% Na-alginate & HPMC K4M: HPMC K100LV (1:2) give the better formulation and produce pharmaceutically acceptable parameters.
Dhaka Univ. J. Pharm. Sci. 21(1): 25-31, 2022 (June)
Phyto-pharmacological Investigations of Leaves of Cissus trifoliata (L.)
Authors: Islam Mehedi , Sikder Md Al Amin , Rashid Mohammad A , Hossain Md Khalid
Published: June 2022

Repeated chromatographic separation and purification of dichloromethane soluble partitionate of methanol extract of leaves of Cissus trifoliata (L.) yielded a total of four compounds, namely β-sitosterol (1), β- sitostenone (2), epifriedelanol (3) and friedelin (4). The structures of the isolated chemical compounds were established by high field nuclear magnetic resonance (NMR) analyses, comparison with previously published data and co-TLC with authentic samples, whenever possible. Compounds 1-4 appeared to be the first time they were identified in this plant species. The methanol extract of C. trifoliata was assessed for central and peripheral analgesic activities by tail immersion and acetic acid-induced writhing reflex methods, respectively. The crude extract demonstrated significant central and peripheral analgesic efficacy at 200- and 400-mg/kg b.w. in mice model. The general toxicity of the extractives was assessed through a brine shrimp lethality bioassay, where the ethyl acetate (LC50=0.88 μg ml–1) and dichloromethane (LC50=0.93 μg ml–1) soluble fractions demonstrated considerable activity. The crude extract at 400 mg/kg (b.w.) also displayed significant antidiarrheal activity, whereas its dichloromethane soluble fractions exhibited moderate thrombolytic activity.
Dhaka Univ. J. Pharm. Sci. 21(1): 69-75, 2022 (June)
EL DISEÑO BASADO EN CONOCIMIENTO: EL CASO DE LOS RELOJES DE NOMOS GLASHÜTTE
Authors: Soasti-Bareta Paulo David
Published: June 2022

El artículo examina cómo se manifiesta la dinámica entre agentes, objetos de conocimiento, los contextos de referenciación y la Semiótica Peircieana (SP) en el diseño de artefactos de uso personal, como son los relojes. Se aborda la perspectiva semiótica y del diseño de productos, ya que el objetivo es identificar los conocimientos específicos que permiten una propuesta de significado relevante durante el proceso de diseño. Como marco referencial, se adopta el Desarrollo Basado en Conocimiento (DBC) y la SP, ya que el primero ofrece un enfoque sobre el conocimiento como capital inmaterial, así como el modelo de los Eventos de Conocimiento (EdC). La segunda tiene un carácter fenomenológico que estudia las relaciones más tangibles en los objetos,asociadas a la materialidad y las personas, así como a las relaciones inmateriales asociadas al valor y los significados. Los relojes Ahoi y Autobahn, de la firma NOMOS Glashütte (NG) son analizados en el texto debido al planteamiento de metáforas visuales y al estatus simbólico que han alcanzado como fenómeno cultural posterior a la reunificación alemana. Estos dos impulsores del valor favorecen las innovaciones en el ámbito relojero. El artículo aporta a la expansión del DBC en la escala de productos, al generar el vínculo entre valor y significado, desde lo (in-)material. Los roles de los actores y el papel de la (in-) materialidad plantean unaforma novedosa de interacción para proponer valor, a través de las interpretaciones de la cultura material.Palabras claveCo-creación, cultura material, conocimiento, diseño, producto, semiótica.AbstractThe article examines how dynamics between agents, objects of knowledge and referencing contexts as well as Peirciean Semiotics (PS) are manifested on artifacts design for personal use, such as wristwatches. Semiotics and product design perspectivse are approached, since the objective is to identify the specific knowledge which allows a relevant meaning proposal during design process. Knowledge-Based Development (KBD) and PS are adopted as a referential framework, since the former offers a focus on knowledge as immaterial capital, as well as the Knowledge Events (KE) model. The latter has a phenomenological character that studies the more tangible relationships in objects, related to materiality and people, as well as immaterial relationships associatedwith value and meanings. Wristwatches Ahoi and Autobahn, from NOMOS Glashütte (NG) are analyzed due to the visual metaphors approach and the symbolic status they have achieved as a cultural phenomenon after German reunification. These two value drivers favor innovations in the watchmaking field. The article contributes to the expansion of  KBD on the product scale by generating the link between value and meaning, from the (in)material. Actors’ roles and (in)materiality role pose a novel kind of interaction to propose value, through material culture interpretations.KeywordsCo-creation, Semiotics, knowledge, design, product, Material culture.
Tratamiento y medidas de protección para la víctima en la legislación ecuatoriana.
Authors: Paccha-Chuñir Mélida , Gómez De La Torre-Jarrin Gina
Published: June 2022

El tratamiento y las medidas de protección para la víctima en el sistema penal ecuatoriano, se ha distinguido por ser un tema olvidado en años anteriores, y que hoy en día con la entrada en vigencia del Código Orgánico Integral Penal, se ha dado cambios notorios en el tema de la protección y tratamiento a la víctima. La finalidad de la presente investigación fue analizar la realidad actual de las diferentes normas, códigos, reglamentos y leyes nacionales que nos permitirá encontrar posibles soluciones a la mala aplicación de la ley en relación a las medidas de protección y el tratamiento a las víctimas de delitos penales en el Ecuador. La investigación fue de tipo exploratoria, descriptiva, con un enfoque cualitativo. El método que se usó en este trabajo de investigación fue el analítico, sintético, para ello se consideró la técnica de revisión bibliográfica a través de las fuentes fidedignas recopiladas de revistas nacionales e internacionales. Conclusiones: el tratamiento y las medidas de protección son aspectos que deben ser considerados prioritarios, ya que con el avance de las nuevas sociedades ha inspirado a las víctimas a reclamar con más impulso el libre goce de sus derechos y que se les dé un tratamiento adecuado y se les otorguen las medidas de protección prescritas en la ley penal ecuatoriana vigente, de manera que obliga a los administradores de justicia respetar y hacer cumplir lo estipulado tanto en la normativa ecuatoriana, como en los tratados internacionales de derechos humanos.
Avaliação do conhecimento sobre a COVID-19 entre estudantes de graduação do Instituto do Noroeste Fluminense de Educação Superior (INFES-UFF)
Authors: Silva Arylson Figueiredo da , Miranda Jean Carlos , Semaan Gustavo Silva , Ederli Nicole Brand
Published: June 2022

Em dezembro de 2019, um novo coronavírus conhecido como SARS-CoV-2, causador da COVID-19, emergiu na China e se dispersou pelo mundo, provocando uma pandemia com ares apocalípticos. Desde então, a sociedade teve que adotar novos hábitos de prevenção, como usar máscaras faciais, higienizar as mãos com álcool 70% frequentemente e manter o isolamento social. Ao mesmo tempo, pesquisadores batalharam para desenvolver vacinas que pudessem combater o novo vírus. Diante de um cenário de medo e insegurança, a obtenção de informações corretas e seguras acerca da COVID-19 é de suma importância para que as pessoas se protejam e contribuam para a diminuição do número de casos e de mortes provocados pela doença. Nesse sentido, foi criado o aplicativo Quiz COVID-19, a fim de avaliar o nível de conhecimento dos estudantes de graduação do Instituto do Noroeste Fluminense de Educação Superior (INFES), da Universidade Federal Fluminense (UFF) acerca do novo coronavírus. Setenta e um graduandos dos cursos de Ciências Naturais, Computação, Matemática (Bacharelado), Matemática (Licenciatura) e Pedagogia participaram do Quiz COVID-19. A grande maioria dos graduandos apresentou um conhecimento adequado acerca do novo coronavírus, com uma média percentual de 75% de acertos. Em relação à média percentual de acertos por curso, temos que os graduandos que cursam Pedagogia atingiram a maior média percentual, 80%, seguidos dos que cursam Ciências Naturais, 76%; Matemática (Licenciatura), 75%; Matemática (Bacharelado), 74% e Computação, 71%. O trabalho realizado com os graduandos do INFES-UFF mostra a importância da obtenção de informações corretas e seguras, imprescindíveis para o enfrentamento à pandemia e à infodemia.
A importância da fisioterapia na anorgasmia
Authors: Sousa Klyvia Rodrigues de , Barreira Suely Amorim , Silva Karla Camila Correia da
Published: June 2022

Introdução: A disfunção sexual feminina acontece quando a mulher não consegue concretizar ou tenha qualquer desarranjo relacionado ao desejo sexual, excitabilidade, orgasmo ou dor sexual. A anorgasmia é uma situação clínica, que acomete principalmente mulheres e tem origem por diversas causas, podendo estar relacionada à traumas, alterações físicas ou fisiológicas.  Nos últimos anos houve maior incidência de mulheres com disfunções sexuais, e neste âmbito, surge a fisioterapia como um avanço relacionado ao tratamento e principal alternativa eficaz para mulheres que apresentam essas disfunções.  Objetivo: Proporcionar o embasamento científico para fundamentar os melhores tratamentos fisioterapêuticos para mulheres com anorgasmia, visto que as técnicas fisioterápicas utilizadas são relativamente recentes no tratamento de mulheres com essa disfunção. Metodologia: Trata-se de um levantamento bibliográfico sobre o papel da fisioterapia no tratamento da disfunção sexual feminina. Considerações finais: O tratamento para mulheres acontece com ou sem parceiros. O ato de se “tocar”, conhecer seu corpo e entender como tudo funciona já faz parte do tratamento, e o apoio do parceiro e acompanhamento psicológico traz mais coragem para as mulheres enfrentar este momento.  Atualmente existem diversas técnicas fisioterapêuticas que promovem a melhora das disfunções sexuais, elas devem ser aliadas à conscientização das mulheres e de seus companheiros. Além disso, os fisioterapeutas devem ter embasamento científico na abordagem ao tratamento e permanecer em constante atualizações, demonstrando a eficácia dos tratamentos e responsabilidade na adequação das terapêuticas instituídas de acordo com as principais queixas informadas por cada mulher.
Elementos da vulnerabilidade de adultos com deficiência após lesão neurológica: revisão integrativa
Authors: Aragão Jamilly da Silva , França Inacia Sátiro Xavier de , Coura Alexsandro Silva , Pereira Amanda de Brito Rangel , Basílio Emerson Eduardo Farias , Silva Arthur Felipe Rodrigues , Silva Francilene Maciel Ferreira
Published: June 2022

Objetivo: identificar os elementos da vulnerabilidade de adultos com deficiência motora após lesão neurológica. Método: revisão integrativa, com busca em agosto de 2020 nas bases MEDLINE, LILACS, BDENF, SciELO e PubMed. A síntese e interpretação dos resultados incidiu à luz da Teoria das Transições de Meleis e do conceito de vulnerabilidade de Ayres.  Resultados: selecionou-se 77 artigos, com predomínio de artigos publicados no ano de 2014, realizados no Brasil, com amostra de pessoas com lesão medular, com nível de evidência VI, derivados do portal PubMed e publicados na língua inglesa. Houve predomínio de elementos na dimensão Pessoal/Individual, com maior frequência referente à condição física.  Conclusão: Identificou-se elementos facilitadoras e inibidoras de vulnerabilidade na dimensão Pessoal/Individual, Sociedade/Social e Comunidade/Programática.
Aposentadorias por invalidez em Servidores Públicos em Universidade Federal no Sul do Brasil – Estudo transversal
Authors: Barreto Verônica Figueiredo , Böhlke Maristela , Barreto Filho Danilo
Published: June 2022

A pesquisa tem por objetivo apresentar o perfil epidemiológico e as principais doenças que provocaram aposentadorias por invalidez em servidores públicos de uma universidade federal. Trata-se de um estudo transversal, retrospectivo, cuja população-alvo foi de servidores públicos que necessitaram ser aposentados por invalidez em uma universidade federal, no período de 2015 até 2019. Foram analisadas as seguintes variáveis: idade, sexo, lotação de trabalho, cargo e causa da aposentadoria por invalidez. No período estudado, 16 servidores necessitaram se aposentar por invalidez. A maioria apresentava idade superior a 40 anos (N=14, 87.5%), ocupava os cargos de auxiliar de enfermagem (N=5, 31.25%) e de professor (N=5, 31.25%), lotados no Câmpus Saúde (N=9, 56.25%). As principais causas de aposentadoria por invalidez foram os transtornos mentais e comportamentais (N=5, 31.25%), seguidos por neoplasias, doenças do aparelho circulatório e do sistema osteomuscular e conjuntivo, cada uma com 3 aposentadorias por invalidez, representando 18.75% das mesmas. Verificou-se com este estudo ser importante avaliar mais cuidadosamente as condições de trabalho dos servidores do Câmpus Saúde e os servidores dos cargos de auxiliar de enfermagem e de professor, no intuito de prevenir o adoecimento e a necessidade de aposentadorias por invalidez.
THE EFFECT OF SOCIAL MEDIA MARKETING ACTIVITIES TO PURCHASE INTENTION
Authors:   Jurusan Manajemen, Fakultas Bisnis, Universitas Katolik Widya Mandala Surabaya Indonesia, Dayoh Michellia Lois , Ari Lydia ,   Jurusan Manajemen, Fakultas Bisnis, Universitas Katolik Widya Mandala Surabaya Indonesia, Agrippina Yulika Rosita ,   Jurusan Manajemen, Fakultas Bisnis, Universitas Katolik Widya Mandala Surabaya Indonesia
Published: June 2022

Internet has evolved significantly from its establishment and it proceeds to do so. In addition, the Internet has become a part of people’s daily life. With the increasing number of internet users and various things that can be achieved through the internet, social media is also experiencing developments. This goes the same with marketing concept, where now the traditional marketing is shifted to modern marketing where now many companies use social media for marketing. This is known as social media marketing. Companies do this to enhance their consumer’s purchase intention and simply to promote their products. There are opportunities and new challenges for companies striving to boost their customers' buying intention through social media marketing. Moreover, there must be many aspects that may influence consumer’s purchase intention, precisely Surabaya consumers. Thus, this research is intended to analyze and explore the effect of Social Media Marketing Activities to Purchase Intention with the mediation of Value Equity and Social Brand Engagement of Skincare Somethinc in Surabaya. The data collected from Google Form, hence, there are 222 qualified respondents who live in Surabaya. In addition, the sampling method for this research is purposive sampling and the collected data is analyzed through Structural Equation Modelling (SEM) with SmartPLS 3.0 as the tool.
PENGARUH INDEKS PEMBANGUNAN MANUSIA TERHADAP INDEKS KUALITAS LINGKUNGAN HIDUP DI INDONESIA MENGGUNAKAN REGRESI DATA PANEL
Authors: Ramadhantie Salsabila Salmasauzan , Ramadhan Miftahul Jannah , Hasibuan Mike Alpiyunita
Published: June 2022

Environmental problems are still a chore for the government and the community. Humans are one of the factors that destroy the environment, which plays a big enough role. This study aims to analyze the influence of the Human Development Index on the Living Environment Quality Index in 34 Indonesian Provinces from 2016-2018. The variables used in this study, the Human Development Index (IPM) in 34 Provinces in 2016-2018 as X variable and Living Environment Quality Index (IKLH) in 34 Provinces in 2016-2018 as a Y variable. The analytical method used for this study is the panel data regression fixed effect model (FEM) with Cross Section Weight. Panel data regression analysis is a regression analysis with data structure which is a combination of cross section data and time series data. Based on the results obtained, the Human Development Index variable significantly influences the Environmental Quality Index in Indonesia. The panel data regression model that was formed was able to explain the variability of the Living Environment Quality Index in Indonesia amounting to 99.65%.
ANALISIS STUDI KASUS KRISIS KETERSEDIAN AIR MUSIM KEMARAU DALAM UPAYA MENANGGULANGI PADA MASYARAKAT DESA BUTUH
Authors: Sudarti . , Puspitasari Nila Rayi
Published: June 2022

Water is a source of life that must exist in human life. Water supply crises have hit a lot due to drought disasters from the dry season. Drought is a disaster that occurs slowly due to changes in weather patterns that last a long time. A village that is located in Kediri Regency, namely Butuh Village has experienced a drought. Efforts that must be made can help reduce the impact of extreme climate change disasters. So, this article is used to add insight into the efforts and solutions that can be implemented. Respondents in the study were sixteen respondents with ten respondents who experienced the dry season, five people came to each house for observation. The results of the analysis that the author conducted through interviews resulted in a process carried out by the community by drilling wells and five people using bucket wells. However, if the drilling of wells by means of continuous deepening of the ground hole can have a dangerous impact on the environment. So, the authors provide another solution by making biopores in each house.
KEANEKARAGAMAN JAMUR MAKROSKOPIS DI JALUR CURUG CIBEUREUM, TAMAN NASIONAL GUNUNG GEDE PANGRANGO
Authors: Nurhikmawati Melly Audina , Kurniasih Surti , Awaludin M. Taufik
Published: June 2022

Gunung Gede Pangrango National Park (GGPNP) is a representative type of mountainous tropical rain forest ecosystem that is rich in biodiversity potential. Research on the diversity of Macrofungi has not been widely, especially in the Cibeureum Waterfall Trail, GGPNP. This study aims to study the diversity of Macrofungi in the Cibeureum Waterfall Trail, GGPNP route. The research was carried out from November 2020 to August 2021. Sampling was carried out by the roaming method. The results of the study of Macrofungi in the Cibeureum Waterfall Trail, GGPNP route obtained 2 phyllum, 9 orders, 22 families and 57 species with a total of 1,360 individuals. The value of the Shannon-Wiener diversity index (H') belongs to the medium category, the evenness index (E) is moderate and the dominance index (D) is low. The abiotic conditions in this area based on the recording of temperature, pH, humidity and light intensity indicate conditions that support the life of Macrofungi in the Cibeureum Waterfall Trail, GGPNP route.
POTENSI EKSTRAK CODIUM, HALIMEDA, DICTYOTA, CHONDRUS, GLACILLARIA SEBAGAI SUMBER PIGMEN DAN ANTIOKSIDAN ALAMI
Authors: Haryani Tri Saptari , Hasanah Uswatun , Komala Oom , Lestari Intan , Agustina Dina
Published: June 2022

Macroalgae is one of the marine biological resources that has an important role in terms of economy, as a source of food and medicine that is beneficial to health. This study aims to determine the source of natural pigments and antioxidants extracts of algae Codium, Halimeda, Dictyota, Chondrus, and Glacillaria using acetone, Folin Ciocalteu, and 1,1-Diphenyl-2-Picrylhydrazil (DPPH) reagents. The method includes sampling, measuring water content by gravimetry, making extracts using maceration method, qualitative phytochemical testing, pigment source test for chlorophyll a, chlorophyll b, total chlorophyll, total phenol, and antioxidant activity. Phytochemical test results obtained that all samples contained flavonoid compounds, alkaloids, while Halimeda and Gracillaria extracts did not have terpenoids. The results of the test for the pigment source were the highest value obtained in Chondrus extract, which was 10.0038 mg/g. And from the results of antioxidant activity testing, all sample extracts were obtained including the group with moderate strength (IC50 value) ranging from 100-500).
The Effect of Yeast Starter Variations on the Quality of Virgin Coconut Oil (VCO) Using the Fermentation Method
Authors: Agustine Dine , Gumilang Meylika Mawar , Komalasari Nia
Published: June 2022

Virgin Coconut oil (VCO) is a coconut processed product that has high benefits and economic value. One of the methods of making VCO is the fermentation method. The purpose of this study was to determine the effect of the percentage of 3 types of yeast (starter yeast tape, starter yeast bread (Saccharomyces cerevisiae) and tempeh yeast (Rhizopus sp) on the quality of VCO produced in terms of volume, viscosity, organoleptic(color, distinctive coconut odor) and chemical test (moisture content, acid number, free fatty acid, peroxide number) The manufacturing method used was the fermentation method by varying the percentage ratio of starter for each yeast by 3%, 6%, and 9%. The results showed the addition of starter percentage Yeast has an effect on the volume of VCO produced, moisture content, acid number, free fatty acids, and viscosity These results have met the quality standards according to SNI 7381: 2008 and APCC (Asian and Pacific Coconut Community).
Characterization of Physico-Chemical Levels of β-Carotene and Antioxidant Activity in Dried Carrot Dregs Powder
Authors: Nuraeni Farida , Warnasih Siti , Rizali Vevi Hikmafitri
Published: June 2022

Carrots contain many nutrients needed by the human body, especially as a source of vitamin A. Carrot pulp is a byproduct of the carrot juice process. The utilization of carrot dregs in household waste as food is still low. To increase added value, carrot dregs can be used as an additional ingredient as flour. The process of making dry carrot dregs uses the oven method with variations in drying temperature and time spent drying. The drying temperatures applied in this study were 40◦C, 50◦C, 60◦C and 70◦C with time variations of 17, 22, 27, 32 hours. Physicochemical testing includes yield levels, protein content test using the Kjeldahl method, water content test, ash content test, β-carotene content test using HPLC, vitamin A test, DPPH method antioxidant activity test and organoleptic test. Organoleptic tests in this study include texture, color and smell. The best results were obtained from the assessment of the organoleptic test which had the highest average value, namely carrot dregs dried at a temperature of 50 32C for 32 hours with a value of 6.0, which means the product was rather favored by the panelists.Carrot dregs dried at 50◦C for 32 hours had a yield rate of 19.30%, a moisture content of 4.41%, an ash content of 4.91%, a protein content of 4.07%, the antioxidant test had% inhibition of 661.30 ppm classified as a weak antioxidant. In the dried carrot dregs powder it still contains β-carotene although the level is only 1.92 mg with a vitamin level of 3187.2 IU. This shows that carrot dregs still contain β-carotene and vitamins even though the levels are not high and can function as an antioxidant inhibitor.
THE EFFECT OF FORTIFICATION OF BRANDS AND CHITOSAN ON TEMPEH ON FIBER LEVELS AND PROBIOTIC BACTERIA GROWTH
Authors: Kurniasih Nunung , Dinna Farah , Amalia Vina , Widiastuti Diana
Published: June 2022

Tempeh is a food made from soybean seeds processed through fermentation using Rhizopus sp. This processed food in the form of tempeh contains various nutrients that the body needs such as protein, fat, carbohydrates, and minerals but does not contain enough fiber. Therefore, fortification of rice bran and chitosan was carried out on tempeh. Rice bran is a by-product of rice milling which has a high fiber content. While chitosan is chitin that has removed the acetyl group. Chito-oligosaccharides (COS) contained in chitosan can act as natural prebiotics, preservatives, antimicrobials, lower cholesterol levels and are immunostimulants. The purpose of this study was to determine the fiber content and growth of the probiotic bacteria Lactobacillus acidophilus in soybean tempeh (A), rice bran (B), chitosan (C), the ratio of soybean tempeh: rice bran (6: 3) + 2% chitosan (D) and the ratio of soybean tempeh: bran (6: 2) + 2% chitosan (E). The method used for the analysis of fiber content was gravimetric, while the growth of probiotic bacteria Lactobacillus acidophilus was used to determine the potential of prebiotics contained in samples A, B, C, D, and E. The results obtained in this study were fortification of rice bran and chitosan in tempeh had high levels of fiber and the number of probiotic bacteria cells was higher than soybean tempeh. The higher the bran added, the higher the fiber content and the number of probiotic bacterial cells. while the growth of probiotic bacteria Lactobacillus acidophilus was used to determine the potential of prebiotics contained in samples A, B, C, D, and E. The results obtained in this study were bran and chitosan fortifications in tempeh had higher fiber content and cell counts of probiotic bacteria than soybean tempeh. The higher the bran added, the higher the fiber content and the number of probiotic bacterial cells. while the growth of probiotic bacteria Lactobacillus acidophilus was used to determine the potential of prebiotics contained in samples A, B, C, D, and E. The results obtained in this study were bran and chitosan fortifications in tempeh had higher fiber content and cell counts of probiotic bacteria than soybean tempeh. The higher the bran added, the higher the fiber content and the number of probiotic bacterial cells.
PENERAPAN METODE FUZZY MAMDANI DALAM MENENTUKAN TINGKAT KEBERHASILAN MENGAJAR BERDASARKAN MOTIVASI, KOMPETENSI PEDAGOGIK, DAN CAPAIAN MAHASISWA
Authors: Sari Erina Puspita , Setyaningsih Sri , Wijayanti Hagni
Published: June 2022

Motivated lecturers will encourage students to give and do their best, resulting in good academic results.  Pedagogic competence of lecturers will improve the competence of lecturers in teaching professionally. The purpose of this study is to determine lecturers’level of success in teaching by applying fuzzy method using MATLAB software, in order to determine the impact of motivation, pedagogical competence, and final student achievement (GPA). Data was obtained from survey on lecturers of Faculty of Mathematics and Natural Sciences (FMIPA), Pakuan University, Bogor; as well as secondary data from the quality assurance unit of the faculty.Based on the results of testing the fuzzy Mamdani method on the data, the highest value of teaching success of 8.23 was obtained in 2018 semester 1, which is categorized as high criteria. There are relationships between motivation, pedagogic competence, and student achievement (GPA).  These variables increased by a few points each year.  Highly motivated lecturers as well as relatively good pedagogical competence will have an impact on the final student achievement (GPA); therefore the success of teaching can be categorized as high. Keywords: teaching success, pedagogic,fuzzy Mamdani
KLASTERISASI PENYEBARAN VIRUS CORONA (COVID-19) DI INDONESIA MENGGUNAKAN METODE K-MEANS
Authors: Taqiyyuddin Teguh Ammar
Published: June 2022

Coronavirus Disease 2019 (COVID-19) or commonly called the Corona virus is a new virus that was first confirmed to appear on December 31, 2019. In Indonesia, all of its 34 provinces have confirmed positive cases of the virus. In this study, clustering of the spread of COVID-19 was carried out as an input for the government for a better, focused handling of COVID-19 for all provinces in Indonesia. Clustering is carried out based on the parameters of total positive cases, total cases of death, Recovery Index, Case Fatality Ratio, tracking and isolation ratio, total cases of people under surveillance completed, cumulative total cases of patients under surveillance, population density, and poverty line. In this study, K-means method was used to cluster data. Based on the Elbow test, the recommended number of clusters is three, which can be translated as high, medium, and low risk clusters. The results of this study are expected to be a comparison to updated data, as well as consideration for the government's better performance in handling COVID-19 more effectively and efficiently. Keywords: COVID-19, clustering, K-means
ANALISIS FAKTOR-FAKTOR YANG MEMPENGARUHI KEMATIAN PASIEN COVID-19 MENGGUNAKAN KLASIFIKASI BERSTRUKTUR POHON BINER DENGAN ALGORITMA QUEST
Authors: Mariyam Siti , Faridhan Yasmin Erika , Virgantari Fitria
Published: June 2022

COVID-19 is an infectious disease caused by a type of coronavirus that was only discovered in December 2019. Patients with underlying medical conditions, or comorbidities, have a higher risk of developing severe illness due to COVID-19. The purpose of this study is to classify and analyze the factors which mostly affect the death in COVID-19 patients using QUEST algorithm. The main strengths of QUEST algorithm are unbiased selection of variables and high computational speed.  Data used in this study are primary data of 14 variables on 460 COVID-19 patients taken from Dr. M. Goenawan Partowidigdo Lung Hospital in Cisarua, West Java, from March 2020 to January 2021. Results show that there are three significant factors that affected the death in COVID-19 patients. The first factor is the status of COVID-19 patients. The second and third factors are comorbidities, i.e. hypertension and kidney failure, respectively. The factor which mostly affected the death in COVID-19 patients is patient with probable status, with a mortality rate of 95%. The second most factor affecting the death in COVID-19 is patients with under-surveillance, suspected and confirmed status with kidney failure, where the mortality rate is 60%. The accuracy of the classification tree is 80.6%, which is quite optimal.
PERAMALAN INFLASI DENGAN METODE PARTICLE SWARM OPTIMIZATION – EXTREME LEARNING MACHINE
Authors: Ilmiyah Raudhatul , Rachmatin Dewi , Marwati Rini
Published: June 2022

The Extreme Learning Machine (ELM) method is a learning method on an artificial neural network that is used to solve non-linear problems. In this article, the Particle Swarm Optimization (PSO) method is combined with the Extreme Learning Machine (ELM) method to determine the number of neurons in the hidden layer, so that the results obtained are quite accurate and more efficient in terms of time. Furthermore, the PSO-ELM method was applied to inflation data in Indonesia, and the results showed that the Roots Mean Square Error (RMSE) value in the training process was 0.005487935, and the RMSE value in the testing process was 0.4124935. These results indicate that the PSO-ELM method is suitable for forecasting inflation in Indonesia.
REVIEW: MANFAAT ASAM KLOROGENAT DARI BIJI KOPI (Coffea) SEBAGAI BAHAN BAKU KOSMETIK
Authors: Handayani Retty , Muchlis Fadzilla
Published: June 2022

Chlorogenic acid(Chlorogenicacid,CGA) is one of the secondary metabolites produced from coffee beans. Chlorogenic acid is widely used in cosmetic preparations as an exfoliant (exfoliate). Apart from exfoliating, chlorogenic acid can also be used as an antioxidant, natural cosmetic coloring, antibacterial (acne), cellulite and slimming. In review this, first look at the comparison of the concentration of chlorogenic acid in the two types of coffee, namely Arabica coffee and Robusta coffee. Next, determine several cosmetic preparations that use coffee beans as a natural ingredient which contains chlorogenic acid. The purpose of review thisis to determine the comparison of the concentration of chlorogenic acid from Arabica coffee beans and robusta coffee which can be used in various cosmetic preparations. Based on the data obtained, the highest chlorogenic acid content was found in robusta green coffee beans with a concentration of 6.1-11.3 (g / 100g), while in Arabica green coffee beans with a concentration of 4.1-7.9 (g / 100g). So it can be concluded that the chlorogenic acid content in robusta coffee has a higher content compared to arabica coffee so that robusta coffee is more recommended to be used as a cosmetic raw material.
PENGARUH PEMBERIAN PILL CARD TERHADAP KEPATUHAN MINUM OBAT DAN TEKANAN DARAH PASIEN HIPERTENSI DI RS PMI KOTA BOGOR
Authors: Setiani Lusi Agus , Nurdin Naufal Muharram , Rakasiwi Indriyana Adiesta
Published: June 2022

Pill card merupakan salah satu media yang dapat digunakan sebagai kartu pengingat minum obat untuk meningkatkan kepatuhan terutama untuk pasien yang memiliki regimen terapi yang kompleks seperti hipertensi. Penelitian ini bertujuan untuk melihat adanya pengaruh dalam pemberian pill card terhadap tingkat kepatuhan minum obat dan penurunan tekanan darah pada pasien hipertensi untuk mencapai outcome terapi. Tingkat kepatuhan dinilai menggunakan kuesioner MMAS-8 (Morisky Medication Adherence Scale) dan pemeriksaan tekanan darah untuk melihat outcome terapi pasien. Penelitian ini menggunakan metode quasi-eksperimental dengan rancangan Pretest Posttest Control Group Design yang dilakukan secara prospektif. Subjek pada penelitian terbagi menjadi dua kelompok, yaitu kelompok intervensi dengan pemberian pill card dan kelompok kontrol tanpa pemberian pill card dengan masing-masing sampel berjumlah 29 pasien. Hasil Penelitian menunjukkan bahwa pemberian pill card dapat memberikan pengaruh secara signifikan (p0,05) terhadap tingkat kepatuhan minum obat dan tekanan darah.
POTENSI EKSTRAK REFLUKS KULIT BATANG KAYU MANIS SEBAGAI ANTIJAMUR Candida albicans dan Candida tropicalis
Authors: Djarot Prasetyorini , Utami Novi Fajar , Yulianita Yulianita , Novitasari Novi , Fitriyani Widya
Published: June 2022

Kayu manis (Cinnamomum burmannii) merupakan salah satu tanaman dari famili Lauraceae yang mempunyai potensisebagai antijamur penyebab kandidiasis seperti C.albicans dan C.tropicalis, hal ini disebabkan kulit batang kayu manis mengandung minyak atsiri, flavonoid, polifenol, saponin, dan tannin. Tujuan penelitian adalah mendapatkan obat alternatif untuk mengobati penyakit yang disebabkan oleh jamur C.albicans dan C.tropicalis. Metode esktraksi yang digunakan adalah refluks, menggunakan pelarut yang kepolaran berbeda yaitu n-Heksan (non polar), etil asetat (semi polar), dan etanol 96% (polar). Ekstrak yang diperoleh selanjutnya dilakukan skrining kualitatif untuk kandungan flavanoid, alkaloid, tanin, polifenol dan saponin, diuji daya antioksidanya dan dilakukan penetapan kadar polifenol. Pengujian aktivitas antijamur dilakukan dengan menentukan Konsentrasi Hambat Minimum (KHM) dengan metode dilusi agar dan pengujian Lebar Daerah Hambat  (LDH) menggunakan metode difusi kertas cakram. Hasil penelitian menunjukkan bahwa pelarut etanol 96% menunjukan kadar polifenol tertinggi yaitu 3,89%  dan aktivitas antioksidan terbaik yaitu 66,29 mg/L, kstrak n-heksan mempunyai nilai KHM terbaik 2% dan LDH terbaik pada konsentrasi 8% dengan nilai rata-rata 16.30 mm±0.28 terhadap pertumbuhan C.albicans dan 15.66 mm ± 0.28 terhadap C.tropicalis.
KAJIAN PENGARUH PERBEDAAN METODE EKSTRAKSI TANGKAI BUNGA CENGKEH (Syzygium aromaticum (L) Merr) TERHADAP KADAR EUGENOL
Authors: Sofihidayati Trirakhma , Wardatun Sri
Published: June 2022

Cengkeh (Syzygium aromaticum) merupakan tanaman asli Indonesia. Kandungan utama dalam minyak atsiri dari cengkeh adalah senyawa eugenol. Senyawa ini banyak digunakan dalam perawatan gigi, sebagai antiseptik , analgesik dan efektif melawan sebagian besar bakteri. Beberapa metode ekstraksi seperti destilasi air ataupun destilasi uap telah dilakukan untuk mendapatkan minyak atsiri cengkeh. Penelitian ini bertujuan mengisolasi dan menetapkan kadar senyawa eugenol yang terdapat pada minyak atsiri tangkai bunga cengkeh yang diperoleh dari metode sokletasi dan destilasi air dengan menggunakan pelarut n-Heksan. Penetapan kadar senyawa eugenol dilakukan dengan kromatografi gas. Berdasarkan hasil penelitian diperoleh kadar eugenol ekstrak minyak atsiri tangkai bunga cengkeh metode sokletasi rata-rata sebesar 55,2% sedangkan dengan metode destilasi air tangkai bunga cengkeh didapat 10,96%
EFEKTIVITAS EKSTRAK PEGAGAN (Centella asiatica) DALAM PENCEGAHAN EKSPRESI GEN CASPASE 8 PADA SEL PYRAMIDAL TIKUS MODEL DEMENSIA
Authors: Yuliani Sapto , Kurniati Suci , Iswahyuni Desi , Sofia Vivi , Widyaningsih Wahyu , Bachri Moch. Saiful
Published: June 2022

Penelitian sebelumnya membuktikan bahwa pemberian ekstrak pegagan (Centela asiatica) dapat mencegah peningkatan ekspresi protein caspase 3 dan menurunkan ekspresi Bcl-2 yang berkaitan dengan apoptosis di daerah CA1 dan CA2-CA3 sel pyramidal hippocampus  pada tikus model demensia.  Selain ekspresi protein tersebut, mekanisme apoptosis juga melibatkan protein lain yaitu caspase 8, yaitu protease sistein yang berperan sebagai inisiator apoptosis di jalur ekstrinsik. Tujuan penelitian ini adalah untuk mengetahui efek ekstrak pegagan dalam mencegah ekspresi gen caspase 8 di sel pyramidal hippocampus pada tikus model demensia yang diinduksi dengan trimetiltin (TMT). Sebanyak 30 ekor tikus Sprague Dawley, 3 bulan, jantan, berat 200-300 g dibagi menjadi 6 kelompok.  sebagai berikut: Kelompok Normal dan TMT diberi CMC-Na,  kelompok ekstrak diberi ekstrak dosis 100 (EP-100), 200 (EP-200)  dan 400 mg/kg BB (EP-400), sedangkan kelompok Sitikolin diberi sitikolin dosis 200 mg/kg B. Pemberian perlakuan selama 35 hari.  Injeksi TMT dilakukan pada hari ke-8 perlakuan dengan dosis 8 mg/kg BB secara intraperitoneal, kecuali pada kelompok normal. Pada hari ke 36 tikus dikorbankan, otak diambil, kemudian bagian hippocampus dipisahkan untuk pembuatan preparat imunohistokimia untuk pengamatan ekspresi gen caspase 8 di sel pyramidal daerah CA1 dan CA2CA3. Jumlah sel yang mengekspresikan gen caspase 8 pada sel pyramidal di daerah CA1 dan CA2CA3 dianalisis dengan uji anava satu jalur dilanjutkan dengan uji LSD dengan tingkat signikansi 0.05. Hasil penelitian menunjukkan bahwa pemberian TMT meningkatkan secara signifikan jumlah sel yang mengekspresikan caspase 8 di daerah CA1 namun tidak pada daerah CA2CA3. Pemberian ekstrak pegagan dosis 400 mg/kg BB menurunkan secara signifikan ekspresi caspase 8 namun tidak terjadi pada dosis 100 dan 200 mg/kg BB. Dengan demikian ekstrak pegagan berpotensi dikembangkan untuk  mencegah demensia.
EXTRACTION OF ROBUSTA COFFEE BEANS (Coffea canephora) FROM WONOSOBO BY ULTRASONIC WAVES AND ANTICANCER TESTS
Authors: Hasan Akhmad Endang Zainal , Utami Novi Fajar , . Mona
Published: June 2022

Wonosobo Robusta coffee beans are one of the natural source ingredients that potentially could be used as ananticancer. It contains polyphenolic compounds such as chlorogenic acid, flavonoids, and hydroxy hydroquinone. Thisresearch aims to determine the optimum conditions for the extraction temperature and time of the Ultrasonic-Assisted Extraction (UAE) method on the extract yield and to determine the anticancer activity. Extraction optimizations wereanalyzed using Response Surface Methodology (RSM) with Central Composite Design (CCD) experimental design on atemperature factor of 40, 50, 60 ºC and extraction times of 10, 30 and 50 minutes. Determination of anticancer activitywas conducted using the Methyl Thiazole Tetrazolium (MTT) Assay method against MCF-7 cells. The optimization results indicate that the temperature of 52.74 ºC and time of 29,53 min are the optimum conditions for extraction with an extract yield of 9,16%. The anticancer activity test result at a concentration of 400 µg/mL is 83,25% so it has the potential to be used as an anticancer.
THE EFFECT OF FOREIGN AND DOMESTIC INVESTMENT AND GOVERNMENT SPENDING ON GROWTH CENTRAL KALIMANTAN PROVINCE ECONOMY 2015-2019
Authors: Huda Nurul
Published: June 2022

The purpose of this study was to determine the effect of foreign and domestic investment variables and government spending on gross regional domestic product in Central Kalimantan Province. The analytical tool used is multiple linear regression with panel data, from the test results obtained the value of the coefficient of determination R2 is 0.981, this indicates that the ability of the independent variable to explain the dependent variable is 98.10%. The results of the study conclude that simultaneously foreign investment, domestic investment, and government expenditure have a positive and significant effect on gross regional domestic product, with the results of the F statistic of 16.798 being greater than the F table of 4.737, while the results of the partial test show that investment foreign investment, domestic investment and government spending have a significant effect on gross regional domestic product.