bluuebunny/crossref_metadata_2025 huggingface dataset:
Decellularized vascularized bone grafts as therapeutic solution for bone reconstruction: A mechanical evaluation
Authors: Heller Ugo , Evrard Robin , Lengelé Benoit , Schubert Thomas , Kadlub Natacha , Boisson Jean
Published: January 2023

Introduction

Large bone defects are challenging for surgeons. Available reimplanted bone substitutes can’t properly restore optimal function along and long term osteointegration of the bone graft. Bone substitute based on the perfusion-decellularization technique seem to be interesting in order to overcome these limitations. We present here an evaluation of the biomechanics of the bones thus obtained.

Material and methods

Two decellularization protocols were chosen for this study. One using Sodium Dodecyl Sulfate (SDS) (D1) and one using NaOH and H2O2 (D2). The decellularization was performed on porcine forearms. We then carried out compression, three-point bending, indentation and screw pull-out tests on each sample. Once these tests were completed, we compared the results obtained between the different decellularization protocols and with samples left native.

Results

The difference in the means was similar between the tests performed on bones decellularized with the SDS protocol and native bones for pull-out test: +1.4% (CI95% [-10.5%– 12.4%]) of mean differences when comparing Native vs D1, compression -14.9% (CI95% [-42.7%– 12.5%]), 3-point bending -5.7% (CI95% [-22.5%– 11.1%]) and indentation -10.8% (CI95% [-19.5%– 4.6%]). Bones decellularized with the NaOH protocol showed different results from those obtained with the SDS protocol or native bones during the pull-out screw +40.7% (CI95% [24.3%– 57%]) for Native vs D2 protocol and 3-point bending tests +39.2% (CI95% [13.7%– 64.6%]) for Native vs D2 protocol. The other tests, compression and indentation, gave similar results for all our samples.

Conclusion

Vascularized decellularized grafts seem to be an interesting means for bone reconstruction. Our study shows that the decellularization method affects the mechanical results of our specimens. Some methods seem to limit these alterations and could be used in the future for bone decellularization.
Evaluation of first and second trimester maternal thyroid profile on the prediction of gestational diabetes mellitus and post load glycemia
Authors: Mennickent Daniela , Ortega-Contreras Bernel , Gutiérrez-Vega Sebastián , Castro Erica , Rodríguez Andrés , Araya Juan , Guzmán-Gutiérrez Enrique
Published: January 2023

Maternal thyroid alterations have been widely associated with the risk of gestational diabetes mellitus (GDM). This study aims to 1) test the first and the second trimester full maternal thyroid profile on the prediction of GDM, both alone and combined with non-thyroid data; and 2) make that prediction independent of the diagnostic criteria, by evaluating the effectiveness of the different maternal variables on the prediction of oral glucose tolerance test (OGTT) post load glycemia. Pregnant women were recruited in Concepción, Chile. GDM diagnosis was performed at 24–28 weeks of pregnancy by an OGTT (n = 54 for normal glucose tolerance, n = 12 for GDM). 75 maternal thyroid and non-thyroid parameters were recorded in the first and the second trimester of pregnancy. Various combinations of variables were assessed for GDM and post load glycemia prediction through different classification and regression machine learning techniques. The best predictive models were simplified by variable selection. Every model was subjected to leave-one-out cross-validation. Our results indicate that thyroid markers are useful for the prediction of GDM and post load glycemia, especially at the second trimester of pregnancy. Thus, they could be used as an alternative screening tool for GDM, independently of the diagnostic criteria used. The final classification models predict GDM with cross-validation areas under the receiver operating characteristic curve of 0.867 (p<0.001) and 0.920 (p<0.001) in the first and the second trimester of pregnancy, respectively. The final regression models predict post load glycemia with cross-validation Spearman r correlation coefficients of 0.259 (p = 0.036) and 0.457 (p<0.001) in the first and the second trimester of pregnancy, respectively. This investigation constitutes the first attempt to test the performance of the whole maternal thyroid profile on GDM and OGTT post load glycemia prediction. Future external validation studies are needed to confirm these findings in larger cohorts and different populations.
El delito político subversivo anarquista y la interpretación de la norma más allá de la ley: los casos de Numen y el proceso de los subversivos 1919-1920, Chile
Authors: Vásquez Saavedra Julia
Published: January 2023

Esta investigación cuestiona la noción de delito político por subversión utilizado contra los anarquistas chilenos durante las primeras dos décadas del siglo XX, el cual fue aplicado reiteradamente contra los anarquistas, lo que los volvió los enemigos internos por antonomasia de la elite gobernante. Se realiza un análisis de dos casos particulares sucedidos en Chile, el asalto a la Editorial Numen y el Proceso de los Subversivos (1919-1920). Los casos anteriores nos hacen cuestionar la forma de ejercer justicia como una práctica cambiante al servicio de ciertos intereses, o más específicamente de cierta cultura política, la que, comparada con la norma legal, paradójicamente no siempre condenaba prácticas que aparentemente y para el imaginario de quienes detentaban el poder político, eran ilegales y propiciaban el desorden.
Crimen y odio en la vida cotidiana de la Transición española: los ejemplos de Interviú
Authors: Ortega Muñoz Víctor José , Serrano Sánchez Carmen
Published: January 2023

El odio es un sentimiento primario e inevitable, que en su máximo apogeo y sin frenos sociales o culturales genera conflictos e infortunios. A través de las páginas de Interviú durante el periodo conocido como Transición, nos aproximamos a las noticias de sucesos con el fin de analizar aquellos actos que tienen el odio como protagonista, los discursos que se elaboran en torno a dichas acciones y la sociedad en la que se producen, desde el punto de vista de la Historia social y la Historia de las mujeres.
El tratamiento jurídico del discurso del odio a ambos lados del Atlántico: ¿referentes para España?
Authors: Ferrari Puerta Alberto José
Published: January 2023

El presente trabajo trata de comparar el tratamiento jurídico del discurso del odio en Estados Unidos y en el Consejo de Europa. En el primero este tipo de discurso forma parte de la libertad de expresión, la cual goza de unos amplísimos márgenes en este país; por su parte, en el segundo estos discursos pueden ser legítimamente restringidos, lo cual responde al modelo de democracia militante que impera en el Consejo de Europa. Una vez analizados ambos modelos, se analiza en qué medida podrían servir de referencia para el ordenamiento jurídico español.
Prácticas de dialectología sincrónica española
Authors: Alonso Pascua Borja
Published: January 2023

Las 250 prácticas que recoge este libro aspiran a llenar un vacío en el repositorio de materiales de que disponen el docente y el estudiante de dialectología española. La obra se organiza en seis bloques de ejercicios respectivamente dedicados al asturiano-leonés, el aragonés, el español noroccidental, septentrional, oriental y meridional —subdividido este último en andaluz, extremeño y canario—, además de dos baterías de prácticas sobre dialectología general e ibérica y sobre otros fenómenos dialectales del castellano. Las actividades que se proponen no se conciben como preguntas cuyas respuestas deban simplemente ser localizadas en un manual, sino más bien como problemas que estimulen al estudiante para poner a funcionar sus conocimientos y extraer conclusiones acerca de las cuestiones lingüísticas que analiza. Se pretende con ello que el alumno busque explicaciones a esos fenómenos y que lo haga manejando adecuadamente la terminología propia de la disciplina, que sea consciente de las dificultades que entraña el estudio de la variación y que trate, en definitiva, no solo de afianzar los conocimientos teóricos que ha adquirido sobre la materia, sino también de hacer por sí mismo dialectología ofreciendo respuestas a los interrogantes que se le plantean.
Learning to Teach Without Teaching: A Mixed Methods Case Study of Preservice Teachers’ Efficacy Beliefs and Perceptions of an Evidence-based Creative Arts Subject
Authors:   Charles Sturt University, Deehan James , Hutchesson Rachael ,   Charles Sturt University, Bathurst, Parker Paul ,   Charles Sturt University, Bathurst
Published: January 2023

Recognition of the inherent value of the Creative Arts in society seldom extends beyond rhetoric to meaningful action. The powerful ways the Creative Arts are positioned within curriculum documents, for example, stand in contrast to entrenched problems such as poor teacher attitudes, disengaging teaching practices and low status. Initial Teacher Education (ITE) programs and preservice teachers are essential to the long-term improvement of Creative Arts education. Creative Arts in ITE is also an interesting context in which to examine the divide between Subject Matter Knowledge (SMK) and Pedagogical Knowledge (PK) that has influenced both educational research and policy. This paper reports on a mixed methods case study of 24 preservice teachers’ Creative Arts teaching efficacy beliefs and perceptions as they completed an evidence-based, discipline-focussed creative arts subject. The Likert scale efficacy data, collected via the CATEBI-B, modified from the established STEBI-B (Enochs & Riggs, 1990), were analysed via MANOVA with repeated measures and T-tests. These analyses were complemented by thematic analysis of qualitative survey data. Results showed statistically significant increases in participants' personal Creative Arts teaching efficacy upon completion of the subject. The significance of Creative Arts teaching outcome expectancy increases was questionable and the qualitative results were somewhat mixed despite being mostly positive. Implications of these findings and directions for further research in this space are discussed.
‘In the West of traditions, 1793 was yesterday’: Royalism at the 1889 Decennial Exhibition
Authors: Stevenson Glynnis
Published: January 2023

My dissertation, tentatively titled ‘The bleus and the blancs: Political Division, Compromise, and the French Revolution at the 1889 Exposition Universelle’, explores the revolutionary-themed paintings on display in the Decennial exhibition celebrating the past decade of art against the backdrop of a tense political election. The event, a spectacle heralding France’s "progress,” was criticized at the time on the left for insufficiently celebrating the legacy of French Revolution. This paper is a portion of my chapter on royalism at the 1889 Decennial art exhibition at the world’s fair, focused on the martyr cult of the western French royalist leader, Charette. Nearly one hundred years after his execution, he appeared at the Decennial in the form of Julien Le Blant’s acclaimed 1883 painting The Execution of Charette. This painting provides a case-study for thinking about the political mobilization of past trauma. A 1969 interview with Charette’s descendants who owned the painting was aptly subtitled “In the west of traditions, 1793 was yesterday” and it speaks to simmering resentment against the political descendants of the Revolution with modern repercussions. With this paper, I analyze paintings aligned with royalist ideology to probe the legacy of the French founding myth of the Revolution and the modern relevance of the politics of memory. 
Moderasi Keberagamaan dan Nilai Sosial Dalam Pemikiran Mukti Ali
Authors: Ahmad Rizal Derry , Maksun Slamet , Dwi Cahyati Ernah
Published: January 2023

This article aims to describe the religious moderation that exists in Indonesia with the perspective of Mukti Ali's thoughts. In this article method, it uses library research. The understanding of religious moderation conveyed in Mukti Ali's thinking, harmony, and harmony that exist in society are the basic values that must be possessed by everyone. As it becomes a basic value that every society must have, it will foster social values in religion. The conclusion of this article is that Indonesian society has not fully applied the understanding of religious moderation. Field evidence shows that there are several cases that occur in Indonesia on behalf of certain religious groups. This requires a re-evaluation of the understanding or implementation of the value of religious moderation.
Keyword: Moderasi Beragama, Mukti Ali, Sosial
Sewa Menyewa Dalam Perspektif Ekonomi Islam
Authors: Ali Ridlo
Published: January 2023

Abstract
The purpose of this study is to describe how leasing in the perspective of Islamic economics. The research method used is qualitative research with a literature study approach. This research is limited and carried out from January 2021 to November 2021.The results showed that the pelungguh rental in Padukuhan Seneng, Siraman Village, Wonosari District, Gunungkidul Regency, Yogyakarta Special Region Province was carried out by the head of the hamlet as the recipient of the pelungguh who rented out (Mu'jir) and the community as tenants (Mus'ta'jir). While the governor's Regulation number 34 of 2017 concerning the utilization of Village Land, the lease is carried out by the Village Government, the proceeds of which are given to the Village Government and Village Apparatus receiving the pelungguh. Economically, there is income obtained from the rent for the Village Government and Village Apparatus who receive Pelungguh. Meanwhile, according to Imam Syafi'i, renting is the same as buying and selling. The item being rented must be his. Although the pelungguh does not belong to the village apparatus, based on the Governor's Regulation Number 34 of 2017, the leasing of the pelungguh is allowed, and the one who rents it is the Village Government. The rental of pelunguh by the head of the hamlet is a problem that occurs in the Village Government.
 Keywords: Rent, Tenants, Renters, Pelungguh, Islamic economics
LARANGAN JUAL BELI GHARAR: KAJIAN HADIST EKONOMI TEMATIS BISNIS DI ERA DIGITAL
Authors: Basyariah Nuhbatul
Published: January 2023

The development of transaction and business models in the current digital era requires Muslims to understand the facts and concepts of correct transactions, in order to avoid acts that violate sharia, one of which is transactions that contain gharar. To understand sharia, we must learn from sources of Islamic law, one of which is the hadith of the Prophet Muhammad. This study aims to describe and analyze comprehensively with various sides of the study of economic hadith about gharar in business. This research is a qualitative type with a literature study approach. The results of the study show that there are many hadiths that explain prohibited buying and selling and business transactions due to the presence of gharar or unclear elements. Because it can harm one of the parties to the transaction. A business is said to be permissible or lawful if it is free from all elements of maghrib; maysir, gharar, usury.
AGENSI LAKI-LAKI DALAM PENCEGAHAN KEKERASAN BERBASIS GENDER DALAM KELUARGA: STUDI KELUARGA DESA JETIS, SAPTOSARI, GUNUNGKIDUL
Authors: Khairun Nisa  , Muhammad Mukhlis Ardianto
Published: January 2023

The majority of men are perpetrators of gender-based violence in the family. Meanwhile, men who are not perpetrators of violence, often choose to be the silent majority, because they consider violence to be in the private sphere. Involving men in the discourse and practice of gender-aware education is expected to change the perspective and attitude of men in seeing women. This is done to decide and reduce the number of violence against women and children. This study focuses on the agency of men in efforts to prevent gender-based violence in the family and to achieve gender justice in the family. Using descriptive qualitative methods with observation and interview models, the resource persons were taken from participants who took part in the father's class program and community facilitators from Rifka Aniisa WCC. This study shows that the process of building agent awareness begins through the reinterpretation of religious texts with religious leaders. This interpretation provides new understanding to the participants in the father class discussion regarding relationships with partners based on monotheism. Practical awareness is achieved by agents through assertive communication with partners. Agents reflect on material learned in class with a partner. The results of these reflections become the basis for producing a just social system in the family and society.
Keyword: Gender Equality and Justice, Rifka Annisa, Agen and Strucutre
DINAMIKA HUBUNGAN ANTARA AGAMA LOKAL, AGAMA RESMI, DAN NEGARA
Authors: Arafat Noor Abdillah  , Syafira Anisatul Izah
Published: January 2023

Discrimination against local religions frequently imposes stigmas on Indonesian society, resulting in long-term trauma for their adherents. This does not always result from the perpetrators or the religious practices they perform. Religious institutions and associative organizations that can be formalized by using adherents of certain religions have a huge hand in the dynamics of inter-religious relations. This function cannot be separated from religious elites who have religious authority and create their own personal privileged space to determine collective settlement on the production and reproduction of religious values and teachings, potentially creating problems in religious construction. The writer analyzes this problem with a structural-functional paradigm of the way state rules on serving local religions that used to be discriminatory have been modified. This study aims to look at assumptions based on social stigma towards adherents of local religions and find a resolution to these problems. Its goals are to enhance understanding of the practices of beliefs and local cultural ancestral wisdom, form inclusive religious awareness, and construct positive and moderate inter-religious relations in Indonesia. The consequences show that discrimination in opposition to local religions can be reduced by tightening the socialization of government policies via the participation of religious institutions and associative agencies.

Keywords: Local religions, religious institutions, government policies.
RADIAL EXTRUSION OF A PIPE BILLET WITH INTERNAL LEDGE. EXPERIMENTAL VERIFICATION OF THEORETICAL FORMULAS ON AN UNHARDENED LEAD BILLET
Authors: Vorontsov A. L. , Reshchikov E. O.
Published: January 2023

The goals of experimental verification of theoretical results are formulated. The characteristics of the tools used, the geometric parameters of extrusion experiments, the strength characteristics of deformable materials, and their lubrication are described in detail. Studies of extrusion of a non-hardening material – lead C00, simulating hot deformation, were carried out. The high accuracy of the obtained calculation formulas is confirmed.
PHYSICAL-TECHNICAL PROPERTIES OF VERMICULITE MINERAL DETERMINED BASED ON EXPERIMENTS AND ANALYTICAL PHYSICAL MODELING. Part 2
Authors: Nizhegorodov A. I.
Published: January 2023

In order to develop technologies and technological equipment for processing vermiculite concentrates and conglomerates including sungulite-vermiculite raw materials, it is necessary to define strength, optical and aerodynamic properties of the above-mentioned materials. This paper gives new topical and classified information about these properties obtained by experiments and analytical physical modelling. The results gained by the author of the present paper and other authors supplement existing data about physical properties and constants of vermiculite as building and refractory material with new topical information.
Роль эго-сети фрилансера в увеличении его накопленного капитала
Authors: Картузова Мария Владимировна , Зангиева Ирина Казбековна , Сулейманова Анна Наильевна
Published: January 2023

Под действием ускоренного развития IT-технологий и эпидемиологической обстановки последних лет трудовые практики продолжают трансформироваться. От этого выигрывает и работодатель (возможность привлекать исполнителя под конкретные задачи), и работник (возможность диверсифицировать свою занятость, не будучи привлекательным кандидатом для рынка труда по найму). Как следствие, фриланс посредством электронных платформ остается привлекательной альтернативой работе в штате.
Отличаясь по характеру и времени сотрудничества, данная трудовая стратегия имеет общую черту с работой по найму — важность развития исполнителем сетевых связей. Построенные эго-сети из профессиональных и личных контактов не только облегчают поиск новых заказов, ведение операционной деятельности фрилансера и дают моральную поддержку, но и служат базисом накопленного капитала. Такой капитал позволяет уникально презентовать свой опыт заказчикам, найденным на электронных платформах, несмотря на стандартизированную форму страниц исполнителей.
Цель настоящего исследования — выявить связи между накопленным капиталом фрилансера и характеристиками его эго-сети. В выборку включены фрилансеры, зарабатывающие посредством русскоязычных цифровых платформ. В анализ включены 136 анкет, собранных методом онлайн-опроса на фриланс-биржах Freelancehunt и Workspace. С помощью линейного регрессионного анализа было установлено, что более широкий накопленный человеческий капитал у фрилансера свидетельствует о наличии тесных связей между значимыми для поддержания жизнедеятельности фриланса людьми, входящими в его эго-сеть.
Благодарность. Статья подготовлена в результате проведения исследования в рамках Программы фундаментальных исследований Национального исследовательского университета «Высшая школа экономики» (НИУ ВШЭ). Авторы выражают признательность менеджменту указанных платформ за помощь в предоставлении доступа к респондентам.
Самооценка эффективности обучения и типы трудностей первокурсников в период коронавирусных ограничений
Authors: Габдрахманов Нияз Камилевич , Груздев Иван Андреевич , Лешуков Олег Валерьевич , Терентьев Евгений Андреевич
Published: January 2023

Образовательный опыт на первом году обучения имеет критически важное значение для всей образовательной траектории студента в университете. Исследования показывают, что именно первый курс становится временем, когда происходит первичная академическая и социальная интеграция в университетскую среду, в значительной степени определяющая последующую успешность обучения. В настоящей статье на данных всероссийского опроса студентов рассмотрены трудности, с которыми столкнулись первокурсники российских университетов в период пандемии COVID-19. Анализ ответов более девяти тысяч первокурсников из университетов, представляющих все федеральные округа Российской Федерации, показывает, что к числу ключевых проблем относятся трудности социализации (нехватка коммуникации с преподавателями и другими студентами), организации самостоятельного обучения (сложно долгое время удерживать внимание онлайн, сложно сосредоточиться на самостоятельном изучении материала), а также технические трудности (проблемы со связью, плохие технические условия для дистанционного участия в занятиях). С помощью латентного анализа классов участники опроса были разделены на восемь групп в зависимости от того, с какими трудностями они столкнулись, и принадлежность к этим группам использовалась для предсказания самооценки эффективности обучения. Результаты анализа свидетельствуют о том, что трудности с социализацией и организацией самостоятельного обучения являются более сильными предикторами низкой самооценки эффективности обучения по сравнению с техническими трудностями. Это указывает на важность системной работы университетов по обеспечению возможностей для коммуникации студентов между собой и студентов с преподавателями, а также развития навыков самостоятельного обучения для студентов-первокурсников в условиях дистанционного и гибридного обучения. 
Благодарность. Авторы выражают благодарность М.О. Абрамовой и Центру социологии образования Томского государственного университета за продуктивную работу в рамках совместного научно-исследовательского проекта.
Креативные пространства как «третьи места» в регионах России
Authors: Кузинер Евгения Николаевна , Петрунина Дарья Сергеевна
Published: January 2023

Статья посвящена исследованию роли креативных пространств в российских региональных центрах с высоким уровнем молодежной миграции — Пскове, Петрозаводске и Сыктывкаре. Наличие креативных пространств может служить одним из аспектов развития города, влиять на привлекательность региона для туризма и инвестиций, а также на миграционные изменения. В данном исследовании анализируются творческие пространства в малых городах. Авторы рассматривают креативные пространства через призму исследований креативной экономики и концепции «третьих мест». Используя метод кейс-стади, они анализируют креативные пространства с фокусом на региональной специфике их организации и взаимодействии с местными сообществами. Эмпирическая база исследования состоит из 45 полуструктурированных интервью по трем исследуемым городам (23 интервью с молодежью, 11 экспертных интервью и 11 интервью с организаторами и сотрудниками/волонтерами креативных пространств), а также дневников наблюдения. В результате анализа были выделены два типа организации пространств: 1) «сверху» по инициативе городских властей и 2) малыми инициативными группами горожан «снизу». Креативные пространства являются отдельной формой «третьих мест», не только выполняющих коммуникативную функцию, но и предоставляющих местным сообществам площадку для самовыражения и производства локальной идентичности, что может выступать одним из факторов, удерживающих молодежь в регионе.
Благодарность. Исследование выполнено при финансовой поддержке Российского научного фонда в рамках проекта Центра молодежных исследований НИУ ВШЭ Санкт-Петербург «Выбор жизненных стратегий талантливой молодежью и ее роль в повышении конкурентоспособности российских регионов как ответ на глобальные вызовы “утечки мозгов”» (грант № 21-18-00122). Авторы благодарят коллег из Центра молодежных исследований, участвовавших в сборе эмпирических данных.
Adherencia al ejercicio físico y mejora en parámetros físicos y psicológicos en una persona mayor. Análisis de caso.
Authors: Pérez Córdoba Eugenio Antonio , Estrada Contreras Omar , Rivas Campoy Paula
Published: January 2023

La evidencia científica sustenta que la práctica del ejercicio genera beneficios físicos, y psicológicos en las personas mayores, pero para conseguirlos es necesario una adherencia en los programas adaptados a sus necesidades. El objetivo de la intervención es iniciar en la práctica físico-deportiva a una persona mayor de 80 años, con un estilo de vida sedentario y con enfermedades crónicas. Para ello, se trabajó en su motivación utilizando herramientas psicológicas como el establecimiento de metas, el refuerzo positivo y el entrenamiento en autoinstrucciones. Los resultados obtenidos mostraron incrementos positivos en los parámetros físicos y en las variables psicológicas como percepción de calidad de vida, de autoeficacia general, en la regulación de la motivación y en un aumento de comportamientos autónomos. De acuerdo a los resultados obtenidos, se cumplió con el objetivo de este estudio, ya que la participante pudo comenzar y completar el programa de entrenamiento personalizado. De esta manera podemos decir que la combinación de ejercicio físico junto con el entrenamiento en habilidades psicológicas puede mejorar la adherencia a los programas de entrenamiento y por ende en obtener beneficios en la salud de las personas mayores.
Bats in the Maldives: a review of historical data and first record of a vagrant Long-winged Tomb Bat (Emballonuridae: Taphozous longimanus)
Authors: Anderson R. Charles , Chakravarty Rohit , Raman Sreehari
Published: January 2023

The Maldives is a country made up entirely of coral atolls with very limited terrestrial habitat diversity and only one known resident bat species: the Maldivian Flying Fox, Pteropus medius ariel. Here we report the first confirmed record of any insectivorous bat from the Maldives: a single bat that flew on board a boat off Raa Atoll in the north of Maldives on 13 February 2019. Wind trajectory analysis suggests that it had flown from Kerala, south India. From photos and morphometric estimates, we could identify it as a Long-winged Tomb Bat Taphozous longimanus. Reports of Flying Foxes from the Maldives (P. medius ariel and P. hypomelanus maris) are also reviewed. The former is widespread and common, while the latter is known only from a single disputed and now apparently missing specimen.
Addendum: Camiña et al. (2022) Impacto en los quirópteros de dos parques eólicos en el Valle del Ebro (Zaragoza) y propuesta de mitigación
Authors: Camiña Álvaro , Antonio Pinzolas José , Inmaculada Ibañez María , Vicente Nana , García-Albi Hernando
Published: January 2023

Esta adenda incluye los resultados del segundo año del monitoreo post-construcción de dos parques eólicos en el Valle del Ebro en la provincia de Zaragoza, además de hacer una corrección a nuestro trabajo anterior. En 2021 detectamos 168 colisiones de murciélagos entre marzo y octubre, lo que representa un descenso del 46.2% respecto al año 2020. Se encontraron tres especies más colisionada, el murciélago rabudo Tadarida teniotis, el murciélago de cueva Miniopterus schreibersii y el nóctulo pequeño Nyctalus leisleri. Empleando las tasas de detectabilidad anteriores de 0,2 y 0,4 y los valores de 3,46 y 6,97 días como tasas de permanencia de los cadáveres y frecuencia entre visitas respectivamente, la estima de siniestralidad fueron de 188-751 murciélagos (17,06-68,26 murciélagos/aero/año, equivalentes a 5,84-23,35 murciélagos/ MW/año). Estos resultados se solapan ligeramente con los obtenidos en 2020. Por ello, concluimos que el descenso de siniestralidad observado puede no ser real. Hemos revisado además más informes del Plan de Vigilancia Ambiental de la consultora. Detectamos carencias importantes en el estudio de la actividad de los murciélagos así como en el número de colisiones que detectaron. La detección mediante ultrasonidos añadió una especie adicional a la comunidad de quirópteros, el murciélago orejudo gris Plecotus austriacus. Como estrategia de mitigación proponían instalar cajas refugio para murciélagos, lo que podría incrementar aún más la siniestralidad y constituir un sumidero para sus poblaciones. En conjunto, bien a través de las colisiones o del seguimiento de actividad, la comunidad de quirópteros en la zona asciende de momento a nueve especies. La distribución espacial de las colisiones en los aerogeneradores y la temporal a lo largo de los meses del año muestra una gran similitud en ambos años. Los resultados de ese segundo año de seguimiento refuerzan las conclusiones del trabajo anterior y la idea de desarrollar análisis del impacto acumulativo en un área más extensa, discutiéndose los objetivos de la Comisión de seguimiento creada por el Gobierno de Aragón con esta idea. Además, se valoran las directrices de seguimiento de quirópteros y protocolos de mitigación del Ministerio de Transición Ecológica y Reto Demográfico (MITERD) y su aplicación a los proyectos estudiados.
Perspectives of The Community Regarding Electronic-Based Dengue Vector Surveillance in the COVID-19 Pandemic
Authors: Pujiyanti Aryani , Trapsilowati Wiwik
Published: January 2023

Background: Penjaga is a google form-based application that helps families share their weekly larva monitoring data online. A study of community perceptions of the Penjaga application needs to be carried out to see the advantages and barriers to its implementation. This study measures the response rate and the public's perception of the online larva monitoring application.Method: The study used a cross-sectional design. Data were collected through an online survey involving 284 households in RW 3 and 7 in the South Rejowinangun Village, Magelang City, Central Java Province, in 2021. The online questionnaire includes questions about demographic information, perceptions of the application (convenience of use, duration of use, appearance, and benefits for preventing dengue), barriers to use, and suggestions for application improvement. Data analysis was done descriptively using the Product-Moment correlation statistical test. Results: Most respondents (59.5%) were female and 56.3% had completed their senior high education. Most of the respondents were in their pre-retirement and middle-aged. An average response rate of 86.3 % indicated that the family answered the application questions satisfactorily. The response rate dropped by 5.8 % when the health cadres released the application assistance. The community views the Penjaga application as user-friendly, quick, easy to use and learn, practical, and fascinating. The three most common challenges are the lack of respondents’ cell phone data quota and familiarity with Android devices. This study encourages health cadres to use the app, especially for elderly and non-mobile phone-owning families.
The Effectiveness of Self-Management Book in Patients with Diabetes Mellitus
Authors: Sidiq Rapitos , Widdefrita Widdefrita , Silaban Evi Maria , Nadira Nindy Audia , Handayani Marni , Lubis Heny Indriati
Published: January 2023

Background: Diabetes mellitus (DM) is a non-communicable disease that causes complex health problems globally and nationally. In addition to high prevalence and mortality rates, it has an adverse socio-economic impact. To reduce the adverse impacts of diabetes mellitus on the quality of a patient's life, education on self-management is required. This study aimed to determine the effectiveness of self-management books for people with diabetes in improving their self-management.Method: The research was quantitative, with a quasi-experimental design. The samples were people with diabetes mellitus who never received health education or were not respondents to the chronic/PROLANIS disease service program. The total number of samples was 312 people. Data were collected using guided interviews before the intervention from June 26, 2022, to July 10, 2022, and after the intervention from July 28, 2022, to October 27, 2022. Data were processed through editing, coding, transferring, and tabulating. They were analyzed by univariate and bivariate analysis using a paired t-test, with a 95% confidence degree (α = 0.05). They were descriptively presented in tables. Results: The average value of self-management before and after the intervention was 46.37 and 50.42, respectively. The paired t-test showed a p-value of <0.05 (0.001 < 0.05).  Based on the results, a self-management book was effective in increasing the self-management of people with diabetes. In the future, it is necessary to carry out further research to determine the impact of using this book on improving the quality of life of DM sufferers, especially its impact on the stability of blood sugar in DM sufferers.
Caveolin‐1 inhibition mediates the opposing effects of alcohol on γ‐secretase activity in arterial endothelial and smooth muscle cells
Authors: Rajendran Naresh K. , Liu Weimin , Cahill Paul A. , Redmond Eileen M.
Published: January 2023

Notch is important to vessel homeostasis. We investigated the mechanistic role of caveolin‐1 (Cav‐1) in mediating the effects of alcohol (Ethanol/EtOH) on the γ‐secretase proteolytic activity necessary for Notch signaling in vascular cells. Human coronary artery endothelial cells (HCAEC) were treated with EtOH (0–50 mM), Notch ligand delta‐like ligand 4 (Dll4), and the γ‐secretase inhibitor DAPT. EtOH stimulated Notch signaling in HCAEC as evidenced by increased Notch receptor (N1, N4) and target gene (hrt2, hrt3) mRNA levels with the most robust response achieved at 25 mM EtOH. Ethanol (25 mM) stimulated γ‐secretase proteolytic activity, to the same extent as Dll4, in HCAEC membranes. Ethanol inhibited Cav‐1 mRNA and protein levels in HCAEC. Caveolin‐1 negatively regulated γ‐secretase activity in HCAEC as Cav‐1 knockdown stimulated it, while Cav‐1 overexpression inhibited it. Moreover, Cav‐1 overexpression blocked the stimulatory effect of EtOH on γ‐secretase activity in HCAEC. Although EtOH also inhibited Cav‐1 expression in human coronary artery smooth muscle cells (HCASMC), EtOH inhibited γ‐secretase activity in HCASMC in contrast to its effect in HCAEC. The inhibitory effect of EtOH on γ‐secretase in HCASMC was mimicked by Cav‐1 knockdown and prevented by Cav‐1 overexpression, suggesting that in these cells Cav‐1 positively regulates γ‐secretase activity. In conclusion, EtOH differentially regulates γ‐secretase activity in arterial EC and SMC, being stimulatory and inhibitory, respectively. These effects are both mediated by caveolin‐1 inhibition which itself has opposite effects on γ‐secretase in the two cell types. This mechanism may underlie, in part, the effects of moderate drinking on atherosclerosis.
Alterations of pulmonary vascular afterload in exercise‐induced pre‐ and post‐capillary pulmonary hypertension
Authors: Karvasarski Elizabeth , Bentley Robert F. , Buchan Tayler A. , Valle Felipe H. , Wright Stephen P. , Chang Isaac S. , Granton John T. , Mak Susanna
Published: January 2023

Exercise imposes increased pulmonary vascular afterload based on rises in pulmonary artery (PA) wedge pressure, declines in PA compliance, and resistance‐compliance time. In health, afterload stress stabilizes during steady‐state exercise. Our objective was to examine alterations of these exercise‐associated stresses in states of pre‐ and post‐capillary pulmonary hypertension (PH). PA hemodynamics were evaluated at rest, 2 and 7 min of steady‐state exercise at moderate intensity in patients who exhibited Pre‐capillary (n = 22) and post‐capillary PH (n = 22). Patients with normal exercise hemodynamics (NOR‐HD) (n = 32) were also studied. During exercise in all groups, PA wedge pressure increased at 2 min, with no further change at 7 min. In post‐capillary PH and NOR‐HD, increases in PA diastolic pressure and diastolic pressure gradient remained stable at 2 and 7 min of exercise, while in pre‐capillary PH, both continued to increase at 7 min. The behavior of the diastolic pressure gradient was linearly related to the duration of resistance‐compliance time at rest (r2 = 0.843) and exercise (r2 = 0.760). Exercise resistance‐compliance time was longer in pre‐capillary PH associated with larger increases in diastolic pressure gradient. Conversely, resistance‐compliance time was shortest in post‐capillary PH compared to pre‐capillary PH and NOR‐HD and associated with limited increases in exercise diastolic pressure gradient. During steady‐state, modest‐intensity exercise‐specific patterns of pulmonary vascular afterload responses were observed in pre‐ and post‐capillary PH relative to NOR‐HD. Longer resistance‐compliance time related to greater increases in PA diastolic pressure and diastolic pressure gradients in pre‐capillary PH, while shorter resistance‐compliance time appeared to limit these increases in post‐capillary PH.
Widths of balls and free boundary minimal submanifolds
Authors: Zhu Jonathan J.
Published: January 2023

We observe that the

k

k

-dimensional width of an

n

n

-ball in a space form is given by the area of an equatorial

k

k

-ball. We also discuss the relationship between widths and lower bounds for the area of a free boundary minimal submanifold in a space form ball.
Exploring the Existence of a Short-Run Kuznets Curve: Does the Fourth Industrial Revolution Affect Income distribution?
Authors: Castaldo Angelo , De Bonis Valeria
Published: January 2023

The link between technological change and income inequality is central to the Kuznets hypothesis. In a time of technological transition towards the digitization and intelligentization of manufacturing processes (the fourth industrial revolution), this paper investigates the relationship between economic development and income distribution through the implementation of both a system generalized method of moments (system-GMM) and a semiparametric fixed effects model approach. Based on a panel of 31 European-area countries over a period of 12 years (2007–2018), accounting for the endogeneity bias arising from the transitional dynamics of income inequality and per capita income, our main results confirm the existence of an inverted U-shaped relationship between income inequality and economic development. Moreover, our analysis shows that the change in the share of labour employed in high-tech sectors is the main driver of this evolutionary pattern.
Evaluation of analytical performance of homocysteine LC-MS/MS assay and design of internal quality control strategy
Authors: Zhao Furong , Pan Guoliang , Hong Mo , Zhao Haipeng , Liu Mingli , Wang Shuang , Sun Xiaoyu , Cao Yunfeng
Published: January 2023

Objectives

Liquid chromatography-tandem mass spectrometry (LC-MS/MS) has become a common technique in clinical laboratories in recent years. Because most methods are laboratory-developed tests (LDTs), their reproducibility and quality control (QC) have been controversial. In this study, Westgard Sigma Rules were used to evaluate the analytical performance and establish an individualised internal QC (IQC) strategy for these LDTs.

Methods

Taking the LC-MS/MS LDT method for homocysteine (Hcy) as an example, the ‘desirable specifications’ from the Biological Variation Database were used as quality goals. Based on the external quality assessment (EQA) samples, bias was calculated and the coefficient of variation (CV) was also calculated by IQC measurements for six consecutive months. The analytical performance was evaluated by calculated sigma metrics and an IQC strategy was designed using the Westgard Sigma Rules with run size.

Results

Over 116 days within 6 months, a total of 850 data points were collected for each of IQC 1 and IQC 2. The monthly coefficient of variation CV% was 2.57–4.01%, which was non-significant (p-value: 0.75). The absolute bias% for IQC1 and IQC2 was 1.23 and 1.87%, respectively. The allowable total error (TEa) was selected as 15.5%, Sigma metrics were 4.02 and 4.30, and the analytical performance was ‘Good’. The 13s/22s/R4s/41s multi rules (n=4, r=1) with a run size of 200 samples were suggested for the Hcy IQC scheme. The quality goal index (QGI) values were over 1.2, indicating that trueness needed to be improved.

Conclusions

The analytical performance of the Hcy LC-MS/MS LDT conformed to the Six Sigma rating level, achieving ‘good’ (four Sigma). Clinical practice indicated that calibration bias was the primary factor affecting trueness.
Design and analysis of novel DGS-loaded low-pass filter with wide stopband
Authors: Arican Galip Orkun , Kanbaz Ihsan , Noamadeh Zohreh , Aksoy Ertugrul
Published: January 2023

This article deals with design and development of a novel 7th order low-pass filter with defected ground structures for S-band applications. The proposed LPF structure was comprised of dumbbell shaped interdigital defected ground structures and open stubs as series inductor and shunt capacitor in the pass band. In addition, an equivalent circuit model was derived and optimized to achieve a 3-dB cut off frequency about 4 GHz with a reflection coefficient of better than −20 dB. Moreover, proposed low-pass filter was manufactured on a Rogers RO4003C substrate with a dielectric constant of 3.38, the dissipation factor of 0.0027. The developed LPF has a very flat pass-band with a transmission coefficient less than −0.5 dB and the measured transmission coefficient better than −18 dB in the passband (DC-3.6 GHz). Meanwhile, the prototype has a 20 dB harmonic suppression level in the frequency range from 5.54 GHz up to 43.5 GHz. Furthermore, the measured peak to peak group delay variation was less than 170 ps in the passband. The proposed filter has a very compact size of 195.3 mm2.
Design of dual-band BPFs with high selectivity
Authors: Wang Min , Chen Lei , Zhang Tian Tian , Peng Jia Yi
Published: January 2023

In this article, two dual-band microstrip bandpass filters (BPFs) with high selectivity and independently controllable passbands are designed based on three parallel-coupled lines (TPCLs). The first BPF proposed in this paper is achieved by employing a pair of folded F-type resonators (FFRs) and conventional TPCL structure. By adjusting the above parameters of each FFR, the center frequencies of the two passbands can be controlled easily. In the meantime, TPCL can enhance the coupling between the source and load, and introduce multiple transmission zeros (TZs), which can conduce to a higher selectivity. To obtain superior selectivity, the second BPF is designed based on a novel TPCL. The novel TPCL is based on the traditional one, which further enhances selectivity since transmission paths are doubled. In order to achieve miniaturization and enhance coupling, FFRs are folded. In addition, four transmission zeros (TZs) are generated to improve the selectivity of the two passbands. The measured results of the fabricated BPFs centered at 2.45/3.5 GHz agree well with the simulated ones, which validates the proposed design method.
Streitfragen, Problemfelder und Perspektiven in der Interkulturalitätsforschung
Authors: Liang Yong
Published: January 2023

Angesichts der veränderten Situationen und Bedingungen für interkulturelle Kommunikation (Globalisierung, Migrationsbewegung, digitale Vernetzung etc.) wird in der Interkulturalitätsforschung seit Anfang des neuen Jahrhunderts verstärkt an einer konzeptuellen Neuorientierung gearbeitet. Der vorliegende Beitrag geht exemplarisch-exploratorisch auf die aktuellen Diskurse zum Kultur- und Interkulturalitätskonzept ein und versucht dabei, sowohl die dort ausgetragene Kritik an den „alten“ Konzeptionen als auch die als „neu“ bezeichneten Überlegungen und Ansätze näher zu beleuchten und kritisch zu hinterfragen. Außerdem wird der Frage nachgegangen, warum die neuen Theorien und Modelle kaum in der interkulturellen Praxis umgesetzt werden konnten. Unter den Aspekten eines diskursiv-reflexiven Kulturverständnisses wird schließlich diskutiert, was wir aus den neuen Debatten lernen können.