bluuebunny/crossref_metadata_2025 huggingface dataset:
Therapeutic Potential of Naturally Occurring Benzofuran Derivatives and
Hybrids of Benzofurans with other Pharmacophores as Antibacterial
Agents
Authors: Xu Zhi , Xu Dan , Zhou Wei , Zhang Xiaoyan
Published: November 2021

Gram-positive and Gram-negative pathogens are able to evade the host immune system, persist within the human host, and lead to severe disease and even death. At present, bacterial infec-tions are one of the leading causes of morbidity and mortality across the world. The development of novel antibacterial agents still represents a challenging endeavor, which is mainly attributed to the continuous emergence of more virulent and drug-resistant pathogens. Benzofuran constitutes the core of diverse pharmacologically active compounds, and there are a variety of approved benzofuran-based drugs in the market or currently going through different clinical phases or registration statuses. Benzofurans could exert antibacterial activity through various mechanisms and possess pronounced activity; therefore, benzofuran is a useful skeleton for the discovery of novel antibacterial agents. This review focuses on the recent advancement of naturally occurring benzofuran derivatives and hybrids of benzofurans with other pharmacophores as antibacterial agents, covering articles published be-tween January 2015 and July 2021. The chemical structures and structure-activity relationships are also discussed.
Taurine: A Water Friendly Organocatalyst in Organic Reactions
Authors: Agarwal Shikha , Kalal Priyanka , Sethiya Ayushi , Soni Jay
Published: November 2021

:

Organocatalysis has become a powerful tool in organic synthesis for the formation of C-C and C-X (N, S, O, etc.) bonds, leading to the formation of complex molecules from easily available starting materials. It provides an alternative platform to the conventional synthesis and fulfills the principles of green chemistry. During the last decades, taurine has emerged as a promising organocatalyst in an array of organic transformations in addition to its plentiful biological properties. It is highly stable, easy to store and separate, water-soluble, of low cost, easily available, and recyclable. The present article highlights the recent and up-to-date applications of taurine in organic transformations.
Comparison Between Kidney and Liver Transplant Recipients Admitted
to a Referral Center Regarding Coronavirus-2019 Manifestations in the
Northeast of Iran During Three Peaks of Pandemic
Authors: Aliakbarian Mohsen , Khodashahi Rozita , Sabbagh Mahin Ghorban , Naderi Hamid Reza , Khodashahi Mandana , Jahanian Shahrzad , Moghaddam Maliheh Dadgar
Published: November 2021

Background:

Transplant recipients are at high risk for severe Coronavirus disease-2019
(COVID-19). Transplant recipients are immune-compromised individuals at high risk for severe infection.
This study aimed to compare the presentations and outcomes of liver and kidney transplant
recipients who were infected with COVID-19 in the Iranian population.

Methods:

This cross-sectional study was conducted at Imam Reza and Montaserieh Hospitals affiliated
with Mashhad University of Medical Sciences, Mashhad, Iran, between 2020 and 2021. In general,
52 patients were selected and divided into two groups of the kidney (n=28) and liver (n=24)
transplantation. Two groups were compared in terms of demographic characteristics and clinical
findings.

Results:

Of the 52 patients, severe COVID-19 infection was reported in 61% of the patients. There
was no significant difference between the two groups in terms of symptoms, except for cough
(χ2=8.09; P=0.004), clinical condition, and laboratory symptoms, except for creatinine (Z=14;
P<0.005), alkaline phosphatase (Z=4.55; P=0.03), total bilirubin (Z=8.93; P=0.03), and partial
thromboplastin time (Z=5.97; P=0.01). There was no relationship between the outcome and the use
of immunosuppressive medications (P>0.05). All patients with kidney transplantation survived,
while two cases in the liver transplantation group failed to survive (χ2=2.42; P=0.11).

Conclusion:

The mortality rate was higher in the liver transplant recipients, compared to the patients
who underwent kidney transplantation.
Using Smartwatches to Observe Changes in Activity During Recovery From Critical Illness Following COVID-19 Critical Care Admission: 1-Year, Multicenter Observational Study (Preprint)
Authors: Hunter Alex , Leckie Todd , Coe Oliver , Hardy Benjamin , Fitzpatrick Daniel , Gonçalves Ana-Carolina , Standing Mary-Kate , Koulouglioti Christina , Richardson Alan , Hodgson Luke
Published: November 2021

BACKGROUND

As a sequela of the COVID-19 pandemic, a large cohort of critical illness survivors have had to recover in the context of ongoing societal restrictions.

OBJECTIVE

We aimed to use smartwatches (Fitbit Charge 3; Fitbit LLC) to assess changes in the step counts and heart rates of critical care survivors following hospital admission with COVID-19, use these devices within a remote multidisciplinary team (MDT) setting to support patient recovery, and report on our experiences with this.

METHODS

We conducted a prospective, multicenter observational trial in 8 UK critical care units. A total of 50 participants with moderate or severe lung injury resulting from confirmed COVID-19 were recruited at discharge from critical care and given a smartwatch (Fitbit Charge 3) between April and June 2020. The data collected included step counts and daily resting heart rates. A subgroup of the overall cohort at one site—the MDT site (n=19)—had their smartwatch data used to inform a regular MDT meeting. A patient feedback questionnaire and direct feedback from the MDT were used to report our experience. Participants who did not upload smartwatch data were excluded from analysis.

RESULTS

Of the 50 participants recruited, 35 (70%) used and uploaded data from their smartwatch during the 1-year period. At the MDT site, 74% (14/19) of smartwatch users uploaded smartwatch data, whereas 68% (21/31) of smartwatch users at the control sites uploaded smartwatch data. For the overall cohort, we recorded an increase in mean step count from 4359 (SD 3488) steps per day in the first month following discharge to 7914 (SD 4146) steps per day at 1 year (P=.003). The mean resting heart rate decreased from 79 (SD 7) beats per minute in the first month to 69 (SD 4) beats per minute at 1 year following discharge (P<.001). The MDT subgroup’s mean step count increased more than that of the control group (176% increase vs 42% increase, respectively; +5474 steps vs +2181 steps, respectively; P=.04) over 1 year. Further, 71% (10/14) of smartwatch users at the MDT site and 48% (10/21) of those at the control sites strongly agreed that their Fitbit motivated them to recover, and 86% (12/14) and 48% (10/21), respectively, strongly agreed that they aimed to increase their activity levels over time.

CONCLUSIONS

This is the first study to use smartwatch data to report on the 1-year recovery of patients who survived a COVID-19 critical illness. This is also the first study to report on smartwatch use within a post–critical care MDT. Future work could explore the role of smartwatches as part of a randomized controlled trial to assess clinical and economic effectiveness.

INTERNATIONAL REGISTERED REPORT

RR2-10.12968/ijtr.2020.0102
УСИЛЕНИЕ ФОТОТОКА В СЛОЯХ КВАНТОВЫХ ТОЧЕК GE/SI-МОДАМИ ДВУМЕРНОГО ФОТОННОГО КРИСТАЛЛА
Authors: Двуреченский А.В. , Якимов А.И. , Блошкин А.А. , Кириенко В.В. , Уткин Д.Е.
Published: November 2021

Обнаружено, что встраивание слоев квантовых точек Ge/Si в двумерный фотонный кристалл (ФК) приводит к многократному (до 30 раз) усилению фототока в ближнем ИК-диапазоне, что связывается с возбуждением падающей световой волной планарных мод ФК, взаимодействущих с межзонными переходами в квантовых точках.
ОБОСНОВАНИЕ ФАКТА СДВИГА РЕЗОНАНСНОЙ ЧАСТОТЫ ОБЪЕМНОЙ КОРОТКОЗАМКНУТОЙ UHF-МЕТКИ ПРИ КОНТАКТЕ С МЕТАЛЛОМ
Authors: Эпов И.В.
Published: November 2021

В работе было проведено численное моделирование объемных короткозамкнутых UHF-меток, а также измерение импедансов антенн меток. Результатом работы стало качественное объяснение сдвига резонансной частоты метки при контакте с металлом.
ВЛИЯНИЕ ТЕМПЕРАТУРЫ ПРОЯВЛЕНИЯ НА ШЕРОХОВАТОСТЬ КРАЯ ЭКСПОНИРУЕМЫХ ЛИНИЙ В HSQ-РЕЗИСТЕ
Authors: Шишлянников А.В. , Татаринцев А.А. , Шарапов А.А.
Published: November 2021

В работе проведено исследование влияния температуры проявления на шероховатость края экспонируемых линий в резисте HSQ.
ФЕНОМЕНОЛОГИЧЕСКАЯ МОДЕЛЬ ДЛЯ МЕТОДА НАПРАВЛЕННОЙ САМОСБОРКИ
Authors: Литаврин М.В. , Горнев Е.С. , Матюшкин И.В.
Published: November 2021

В работе приводится компактная модель для симуляции самосборки блок-сополимера. Приведены результаты для самосборки внутри контактного окна, но модель может быть обобщена и на более сложные структуры.
МОДЕЛИРОВАНИЕ РАСПРЕДЕЛЕНИЯ ЭЛЕКТРИЧЕСКИХ ПОЛЕЙ В СТРУКТУРЕ С ЭФФЕКТОМ ПАМЯТИ С ПОРИСТЫМ LOW-K-ДИЭЛЕКТРИКОМ В КАЧЕСТВЕ БУФЕРНОГО СЛОЯ
Authors: Орлов А.А. , Ганыкина Е.А. , Резванов А.А.
Published: November 2021

В работе приведено моделирование распределения электрического поля в структурах с эффектом памяти с пористым low-k-диэлектриком в качестве буферного слоя в зависимости от значений величин открытой пористости.
АНАЛИЗ ЭФФЕКТИВНОСТИ ПРИМЕНЕНИЯ БИНАРНЫХ НЕЙРОННЫХ СЕТЕЙ ДЛЯ РАСПОЗНАВАНИЯ РЕЧИ
Authors: Мошкарова Л.А. , Тельминов О.А.
Published: November 2021

В работе исследуется возможность распознавания русскоязычной речи с применением нормированных по мощности кепстральных коэффициентов и бинарных нейронных сетей.
ПРИНЦИПЫ АВТОМАТИЗАЦИИ МАРШРУТОВ ПРОЕКТИРОВАНИЯ ФОТОШАБЛОНОВ
Authors: Медведев К.А. , Колобов А.В. , Иванов В.В.
Published: November 2021

В работе сформулированы основные принципы автоматизации маршрутов проектирования фотошаблонов и продемонстрировано их применение на примере интеграции маршрутов 180 и 90 нм в рамках единого программного комплекса.
ОПТИЧЕСКИЕ ХАРАКТЕРИСТИКИ МНОГОСЛОЙНОЙ СТРУКТУРЫ С ПРОСВЕТЛЕННЫМИ ПЛЕНКАМИ ФАЗОИЗМЕНЯЕМЫХ МАТЕРИАЛОВ
Authors: Притоцкий Е.М. , Езько Е.П. , Панков М.А.
Published: November 2021

Представлена модель многослойной структуры с просветленными пленками теллурида германия для реализации быстрой многоуровневой модуляции коэффициента пропускания.
ИССЛЕДОВАНИЕ ХАРАКТЕРИСТИК АКТИВНОИНДУКТИВНЫХ ЦЕПЕЙ С ОТРИЦАТЕЛЬНОЙ ГРУППОВОЙ ЗАДЕРЖКОЙ НА ВЕРХНИХ ЧАСТОТАХ
Authors: Тищук Б.Ю.
Published: November 2021

В данной работе было проведено исследование характеристик активно-индуктивных электрических цепей с отрицательной групповой задержкой на верхних частотах. Были разработаны и изготовлены два прототипа, на которых проводились измерения характеристик. Измеренные значения коррелируют со значениями, полученными при симуляции схем прототипов.
Efficient Encryption Algorithm for Data Security in Big Data Cloud Environment
Authors: Kumar K. Praveen
Published: November 2021

Abstract: High speed Internet technology development and data technologies create a huge amount of information in day by day. Use of big data and cloud both are managing traditional data processing and storage issues. At the same time users can face many issues like data security and privacy manner. Here we proposed Blockchain based secure algorithm for to achieve Security and Privacy for big data. Keywords: Security, Blockchain, Big data and Cloud environment
A Case Report on Chronic Intestinal Pseudo-obstruction Presenting as Unspecified Abdominal Pain in an Adult
Authors: Ha Yu-bin , Jang Han-sol , Shin Gil-cho
Published: November 2021

Objectives: This study examined a case of chronic intestinal pseudo-obstruction (CIPO) in an adult with unspecified abdominal pain.Methods: The patient was treated with herbal medicine, acupuncture, and moxa. Treatment progress was evaluated by follow-up monitoring of the intensity, frequency, and duration (in hours) of abdominal pain and body weight.Results: The average abdominal pain level on the Numerical Rating Scale (NRS) and its incidence decreased. The duration of pain was 15 hours maximum and 2.5 hours minimum. The body weight repeatedly increased and decreased but increased overall. Despite no remarkable findings from X-rays, air-fluid levels and coil-shaped folds of the small bowel were observed.Conclusions: Korean medical treatment based on a dialectic effectively relieved chronic abdominal pain and suspected CIPO-a disease that requires continuous management and therapeutic intervention.
A Case Report of Essential Tremors Treated with Yeokhan-san
Authors: Ha Da-jung , Huh Tae-young , Park Sang-eun
Published: November 2021

Objective: This report describes the case of a patient with essential tremors of the mouth and hands, which were improved by Yeokhan-san treatment.Methods: To relieve the symptoms, Korean medicine treatments, including Yeokhan-san, Ohaeng-Hwa acupuncture, and electronic moxibustion, were performed. To evaluate the effects of the treatments, the visual analog scale and Fahn-Tolosa-Marin clinical rating scale for tremor were used.Results: After the treatment, the patient's clinical symptoms were improved. The visual analog scale score decreased from 10 to 2 for the hand tremor and from 10 to 1 for the mouth tremor. The Fahn-Tolosa-Marin tremor scores decreased from 3 to 1 for both the hand and mouth tremors.Conclusions: The present case suggests that Yeokhan-san and Ohaeng-Hwa acupuncture are effective for the treatment of essential tremor.
A Case Report on Drug-induced Liver Injury Induced by Antilipidemic Agents
Authors: Oh Seo-hye , Gwon Gi-hyeon , Park Eun-su , Kim Won-young , Kim Dong-young
Published: November 2021

Objective: This case report describes a patient who suffered a drug-induced liver injury and was treated with Saengganggeonbi-tang.Methods: A patient was treated with Korean herbal medicine, and the treatment effect was evaluated using liver function tests (LFT) to determine total cholesterol and triglyceride levels.Results: The patient’s LFT levels were normal on 27 July 2021 but became abnormal by 12 August 2021 after taking Western drugs. After 15 days of treatment with Saengganggeonbi-tang, the LFT levels had improved.Conclusion: This study shows that Saenggangeonbi-tang may be an effective treatment for drug-induced liver injury.
A Case Report on Spinocerebellar Ataxia Type 2
Authors: An Da-young , Han Seung-hee , Nam Hyun-seo , Han Su-zy , Kim Mi-kyung , Sun Seung-ho
Published: November 2021

Objectives: The purpose of this study was to investigate a case of a patient with spinocerebellar ataxia (SCA) type 2 whose condition improved following treatment with Korean medicine.Methods: A 25-year-old man, diagnosed with SCA type 2, was treated with herbal medicine (Yukmijiwhang-tang-gami), acupuncture, and physical treatment. The therapeutic effect was evaluated using the Berg Balance Scale (BBS) and gait status.Results: Following treatment, the BBS score increased, and gait ataxia improved.Conclusions: This case study suggests that Korean medicine could be effective for relieving symptoms of SCA type 2.
A Case Report on a Patient Treated with Combined Korean Medicine for Chronic Headache with Digestive Symptoms
Authors: Choi Gyu-cheol , Bae Ji-eun , Park Jae-won , Kim Dong-jin , Hong Jeong-su
Published: November 2021

Objectives: The purpose of this study was to examine the effect of combined Korean medical treatment on chronic headache with digestive symptoms.Methods: We collected data from October to December 2020 and evaluated the efficacy of combined Korean medical treatment using the Korean Headache Impact Test-g (KHIT-6), European Quality of Life Five Dimensions (EQ5D) Scale, and Numerical Rating Scale (NRS) at admission, after two weeks of hospitalization, and on discharge.Results: At the end of treatment, the patient had increased EQ5D and reduced KHIT-6 and NRS scores.Conclusions: After the combined Korean medical treatment, the patient showed improvement, suggesting the efficacy of treatment.
Modern and Classical Aspects on Infectious Diseases and their Management w.s.r. to Current Pandemic Situation: A Review
Authors: Kanungo Neeraj , Kumar Ojha Ajit , Kanungo Vijayata
Published: November 2021

The ancient term Sankramaka Roga resembles communicable diseases as per modern science. These diseases mainly arise due to the influence of microbial invasion inside the body. The transmissions of such disease from one person to another take places via various means including Gatra Sansparsha, Prasnaga, sleeping and eating together; sharing objects and sexual contact, etc. The microbial toxin induces pathogenesis of infectious diseases after invasion of microorganism inside the body. Sankramaka Roga turned to Janapadodhwamsa if large numbers of people get affected, this condition can be correlated with resembles situation as per modern science. The modern science described uses of antibiotics and immune-therapy for the management of these diseases. Similarly Ayurveda rely on natural drugs, classical formulations, Panchakarma and Rasayana Chikitsa, etc. to treat Sankramaka Roga. Ayurveda concept of Ahara-Vihara, Dinacharya, Ratricharya, Ritucharya and Sadvritta improves immune system thus helps to prevent pathogenesis of Sankramaka Roga. Present article explores modern and classical aspects on infectious diseases and their management w.s.r. to current pandemic situation.
Clinical importance of Marma w.s.r. to Role in Pathological Condition: An Ayurveda Review
Authors: Jain Sapan , Dange Mrunal
Published: November 2021

Ayurveda as science of life and spiritualism provides many ways of healthy living and focused towards the prevention and treatment of diseases. The observation, supervision and practical understating contributed towards the built up of principles of Ayurveda. Ayurveda presented several concepts related to the physiological functioning and anatomy of body, Marma is one such aspect of Ayurveda considered as resuscitative and penetrable area of the body. These Marma points are presents all over the body including neck, head, trunk & extremities. Marmas points in body mainly built up by groups of muscles, ligaments, vessels, tendons and bones, etc. Marma points are related with Tridosha, Bhutatma and Triguna therefore any injury and trauma to the Marma can lead painful manifestations which may be lethal sometimes. Generally 107 Marma’s described in various Ayurveda literatures which are responsible for many clinical events. The knowledge of Marma points can be utilizes for diagnostic, clinical and therapeutic purposes.
CRITICIZING THE BUGIS ISLAMIC SCRIPT, PAU-PAU RIKADONNA I DARAMATASIA FROM SIRIQ NA PESSÉ PERSPECTIVE
Authors: Bermawy Munthe  , Mustari Mustari , Maharsi
Published: November 2021

Pau-Pau Rikadonna I Daramatasia (PRID) is a very popular story and has an important position in the lives of Bugis people in South Sulawesi as well as in other region. In the script form, the story has three versions: Bone, Barru, and Pangkep. Not only being written in script form, the story is also staged in short films, picture stories, dances, and others. This article aims to understand the meaning for the Bugis' collective awareness of PRID stories. To reveal the meaning, Bone version of PRID will be used with considering the whole story. Bone's PRID is also unique because it has some additions of episodes at the beginning and at the end of the story that become the focus of this article analysis. In understanding the meaning contained in the PRID, Levi Strauss's theory of structuralism will be used by building binary opposition to the depth structure of the text. Based on the analysis conducted, the addition of episodes contained in the PRID version of Bone is closely related to the cultural value ofÂ siriq na pesseÂ (honor and solidarity) which is opposing sharia values. This can be interpreted as an effort by the Bugis to reconcile the two values so that PRID is well thanked and appreciated until now as can be seen in Youtube contents.
Performance and Sustainability of Halal Food Smes
Authors: Qurniawati Rina Sari , Nurohman Yulfan Arif
Published: November 2021

This study investigates the performance and sustainability of halal food SMEs in the FinTech era. The large aggregate contribution of SMEs does not yet reflect good performance in domestic and foreign market competition due to lack of financial literacy. FinTech can support financial literacy so performance and sustainability SMEs will increase. Consequently, testing the effect of fintech and literacy on the performance and sustainability of MSMEs. A total of one hundred respondents are selected using the quantitative method as sources of data collection. The questionnaires are distributed using a purposive sampling method in Surakarta, Indonesia. The software used for analysis is SEM-PLS. Â The results of this study state that the performance and sustainability of SMEs are influenced by FinTech and financial literacy
An investigation into remote sensing techniques and field observations for modeling of dynamic hydraulic roughness from riparian vegetation
Authors: Chaulagain Smriti , Stone Mark , Dombroski Daniel , Gillihan Tyler , Chen Li , Zhang Su
Published: November 2021

Riparian vegetation provides many noteworthy functions in river and
floodplain systems including its influence on hydrodynamic processes.
Traditional methods for predicting hydrodynamic characteristics in the
presence of vegetation involve the application of static roughness (
n) values, which neglect changes in roughness
due to local flow characteristics. The objectives of this study were to:
(1) implement numerical routines for simulating dynamic hydraulic
roughness ( n) in a two-dimensional (2D)
hydrodynamic model; (2) evaluate the performance of two dynamic
roughness approaches; and (3) compare vegetation parameters and
hydrodynamic model results based on field-based and remote sensing
acquisition methods. A coupled vegetation-hydraulic solver was developed
for a 2D hydraulics model using two dynamic approaches, which required
vegetation parameters to calculate spatially distributed, dynamic
roughness coefficients. Vegetation parameters were determined by field
survey and using airborne LiDAR data. Water surface elevations modeled
using conventional and the proposed dynamic approaches produced similar
profiles. The method demonstrates the suitability in modeling the system
where there is no calibration data. Substantial spatial variations in
both n and hydraulic parameters were observed when comparing the
static and dynamic approaches. Thus, the method proposed here is
beneficial for describing the hydraulic conditions for the area having
huge variation of vegetation. The proposed methods have the potential to
improve our ability to simulate the spatial and temporal heterogeneity
of vegetated floodplain surfaces with an approach that is more
physically-based and reproducible than conventional “look up”
approaches. However, additional research is needed to quantify model
performance with respect to spatially distributed flow properties and
parameterization of vegetation characteristics.
Automation of hydrological drought typology to study drought propagation in a tropical catchment
Authors: Quesada-Montano Beatriz , Loon Anne F. Van , Hidalgo Hugo , Westerberg Ida , Birkel Christian , Wetterhall Fredrik
Published: November 2021

Understanding how droughts propagate through the hydrological cycle from
precipitation to streamflow and groundwater is important for improving
water and risk management policies. At the catchment scale, the analysis
of drought propagation and classification into drought types is usually
done manually, which can be time consuming and difficult to replicate.
Here, we developed an automated, objective procedure for classification
of different drought types with the aim to study drought propagation in
the tropics. The method was applied to the Savegre catchment in Costa
Rica as a proof-of-concept. We first confirmed that drought events in
the catchment could be classified into the process-based typology from
the literature: classical rainfall deficit drought, wet-to-dry season
drought, and composite drought. The automation algorithm was able to
replicate the classification obtained with the manual typology with the
exception of two events, and thus it is a development towards objective
and time efficient hydrological drought analysis in tropical catchments.
Most of the detected hydrological droughts (80% and 76% of all river
discharge and baseflow droughts, respectively) were classical rainfall
deficit droughts, which suggests that climate plays a more important
role in drought development than catchment characteristics in this
catchment. However, the importance of catchment characteristics was
revealed by the presence of severe composite drought events and by the
attenuation of significant precipitation droughts.
Factors Associated With Nonattendance in a Nationwide Screening Program for Diabetic Retinopathy: A Register-Based Cohort Study
Authors: Petersen Gabriela B. , Byberg Stine , Vistisen Dorte , Fangel Mia V. , Vorum Henrik , Joensen Lene E. , Kristensen Jette K.
Published: November 2021

OBJECTIVE

The aim of the study was to identify factors associated with nonattendance in a Danish nationwide screening program for diabetic retinopathy among people with type 2 diabetes.

RESEARCH DESIGN AND METHODS

A retrospective observational study linking individual-level register data was performed. First, we compared characteristics of 156,878 people with type 2 diabetes divided into attenders and never-attenders on the basis of their screening history over a 6-year period. Second, we assessed 230,173 screening intervals within the same 6-year period. Mixed-effects models were used to investigate the effect of sociodemographic and health-related factors on the likelihood of having a nonattender interval (i.e., failing to attend screening within the recommended interval).

RESULTS

A total of 42,068 (26.8%) people were identified as never-attenders, having no registered eye screening over a 6-year period. Compared with attenders, never-attenders were more frequently divorced/widowed, lived in the Capital Region of Denmark, and had poorer health. A total of 62,381 (27.1%) screening intervals were identified as nonattender intervals. Both sociodemographic and health-related factors were significantly associated with the likelihood of having a nonattender interval. The largest odds ratios for nonattendance were seen for mental illness, nonwestern descent, divorce, comorbidity, and place of residence.

CONCLUSIONS

Our findings suggest that never- and nonattendance of screening for diabetic retinopathy are more common among people who are divorced/widowed and of poorer health. Additionally, nonattendance is more frequent among people of nonwestern decent. These population subgroups may benefit from targeted interventions aimed at increasing participation in diabetic retinopathy screening.
A Marine-Biology-Centric Definition of Ocean Connectivity and the Law of the Sea
Authors: Johansen Elise , Dahl Irene Vanja , Lott Alexander , Nickels Philipp Peter , Solstad Andreassen Ingrid
Published: November 2021

The inter-connectedness of marine ecosystems has been repeatedly acknowledged in the relevant literature as well as in policy briefs. Against this backdrop, this article aims at further reflecting on the question of to what extent the law of the sea takes account of or disregards ocean connectivity. In order to address this question, this article starts by providing a brief overview of the notion of ocean connectivity from a marine science perspective, before taking a closer look at the extent to which the law of the sea incorporates the scientific imperative of ocean connectivity in the context of four examples: (i) straits, (ii) climate change and ocean acidification, (iii) salmon and (iv) the ecosystem approach to fisheries. Tying the findings of the different examples together, this study concludes by stressing the need of accommodating ocean connectivity not only in the interpretation and implementation of the existing law (of the sea) but also in its further development.
Anerkjennelsens logikk1
Authors: Bøhn Einar Duenger
Published: November 2021

In this essay, I provide an intuitive analysis of “recognition” in the sense of the Norwegian “anerkjennelse”, and the german “anerkennen”. I discuss the word (section 1), the concept (section 2), and the phenomenon (section 3) of such recognition, and especially its philosophical, psychological, moral and political importance.
«Det snakker vi ikke om! Familiehemmeligheter etter krigen»: Et blikk på krigens langtidskonsekvenser i et tre-generasjoners perspektiv
Authors: Pabst Kathrin
Published: November 2021

Under the surface of our societies, there are thousands and thousands of stories which could add nuances and details to a black-and-white picture of historical events. But many of these stories are too private, too personal or too traumatic to share. Feelings like despair, shame or guilt might be associated, and one could be afraid of the reactions of others when telling them. Here, museum institutions and museum professionals might function as mediators and connecting links between those who want to share but do not know how – and those who need to know.

In this article, we present the first results of a documentary- and exhibition project dealing with the long-term consequences of WW2—in the families and in the local societies. 21 informants, mainly from the second and third generation, were questioned about how difficult and traumatic experiences—during or after the war—affected their families and their own feeling of identity. The answers we received showed that especially the not-knowing what has happened often has severe effects on one’s personal life and well-being.
Krigsminner i nye norske romaner
Authors: Langås Unni
Published: November 2021

In this article, I analyze three novelistic projects from the last decade, i.e., Jon Michelet’s six-volume work En sjøens helt (2012–2018), Simon Stranger’s Leksikon om lys og mørke (2018), and Kjartan Fløgstad’s Due og drone (2019). The novels address events during the war but have different agendas in contemporary public debate. Michelet’s errand is to draw attention to the war sailors’ achievements, Stranger’s to remind us of the sufferings of the Jews, as well as to try to understand a Norwegian Nazi, and Fløgstad’s to underpin a thesis about the corruptive workings of capitalism and today’s terrorism’s roots in the past. I show how Michelet uses the suspense genre, and how he writes engaging about his seamen, but recirculates an old-fashioned gender matrix. Stranger involves the reader in the questions he asks and tries to evoke empathy and promote insight but tends to use clichés and a pathologizing discourse to understand the perpetrator. Fløgstad has a deconstructive strategy in his plot development since the novel’s generational pattern, its hero narratives and its subject constitutions are consistently questioned and dissolved. His style is more self-reflective than the other two, due to a saturating ironic rhetoric and a playful attitude to conventions. Finally, I discuss the noteworthy phenomenon, that they all use sexuality to further their conceptualizations of the past in the present.
THE TOPOGRAPHY OF THE HIP JOINT REGION IN THE PRENATAL PERIOD OF HUMAN ONTOGENESIS
Authors: D. I. Yakymiuk
Published: November 2021

The topography and structures of the hip joint region were studied by means of morphological methods in 40 embryos and prefetuses, 28 fetuses and 9 human newborns. The topography of structures of the hip joint region was defined. For the first time, the chronological patterns of development and formation of bone and muscle structures of the hip area and its topographic anatomical formation during intra-uterine development were comprehensively studied. The dynamics of morphometric parameters of muscles, ligaments and osseous structures of the hip joint region were determined.
GENETIC DETERMINATION OF POSTOPERATIVE INTESTINAL PARESIS IN THE BACKGROUND OF PERITONITIS
Authors: Polianskyi I. , Moskaliuk V.
Published: November 2021

Postoperative intestinal paresis remains an urgent problem of abdominal surgery, since it is one of the most common postoperative complications in terms of frequency. In most studies, the violation of the motor function of the intestine after surgery on the hollow organs of the digestive system is considered as a pathological process, is a consequence of postoperative peritonitis. The paper presents data on the relationship between the variants of the SERT gene, which regulates the reuptake of serotonin, with the concentration in the blood plasma and the likelihood of postoperative intestinal paresis and peritonitis. This made it possible not only to predict the occurrence of postoperative disorders of the motor-evacuation function of the intestine, but also to improve the algorithms for their prevention and pathogenetically justified treatment. It has been established that it is with the SS-genotype that postoperative disorders of the motor-evacuation function of the intestine occur more often, which lead to peritonitis. This leads to a change in treatment tactics in such patients. If these unfavorable genotype variants are found for surgery in such patients, we consider it expedient to expand the indications for intestinal intubation even without intraoperative manifestations of its paresis. We have proposed a technique in which nasointestinal intubation of the small intestine is first performed, which is necessary for the main stage of the operation. If it is necessary to withdraw the stoma, the indications for which in patients with unfavorable genotype variants are considered appropriate to expand, the intubation probe is cut off at the first opening, which is placed in the stomach, and the other end is withdrawn through the stoma. This greatly simplifies the technique of bowel intubation, avoids various complications associated with retrograde intubation, and, first of all, wound infection. Studies indicate a high risk of developing postoperative peritonitis in surgical patients who, after surgical interventions on the digestive organs, had pronounced disorders of the motor-evacuation function of the intestine. Improved algorithms for the treatment of such patients make it possible to significantly reduce the risk of developing postoperative intestinal paresis and peritonitis, and, if they occur, to effectively eliminate their manifestations.
Binary terminological units containing the basic seme “erythema”
Authors: Synytsia Valentyna , Myronyk Olena , Teslenko Mariia
Published: November 2021

The article is studied for the first time status of terminological phrases with the basic sema "Erythema" in the structure of the Latin medical terminology.Verbal codification of the selected is traced terminological phrases in modern medical encyclopedic dictionaries. Carried out etymological, morphological, syntactic analysis of binary attributive components of functioning terminological phrases in medical oral and written discourse. Methods research. In the study, the method of continuous sampling, which allowed the selection of actual material; descriptive the method by which the inventory and internalinterpretation of selected terminological phrases; structural method for establishing connections and relationships between linguistic elements. Conclusions. According to the study found that the attributive component in the structure of binary terminological phrases with the basic sema "erythema"outlines the etiological sign, symptoms of the disease, form, consequence, clinical expressiveness, ie, attributive component in each case carries outclassification detail of the denoted phenomenon and thus contributes to the specification of clinical forms of erythema and allows avoid misunderstandings when making a diagnosis. Predominant most terminological phrases with sema "Erythema" consists of binary terminological phrases, formed according to the scheme Subst. nom. sing. + Adject. nom. sing .; model formation of terminological phrases according to the scheme Subst. nom. sing. + Subst. gen. sing./gen. plur. is unproductive; terminological phrases using prepositions refer to unproductive model of term formation.
Peculiarities of use and methods of translation of english adjectives of dimension to denote the general small size (based on the films of the BBC channel “The Blue Planet” and “Life”)
Authors: Berehovenko Natalia , Demchenko Natalia
Published: November 2021

Aim of investigation. This scientific research aims to describe English adjectives of dimension to denote the general small size and ways to reproduce them in Ukrainian and Russian based on BBC films “The Blue Planet” and “Life”. The main research methods are a complex translation, inductive and deductive methods for generalization of the selected language material and derivation of new provisions on the basis of well-known ones. In addition, the method of continuous sampling was also used – to form the body of the studied material; method of comparative and translation analysis of original texts and translations and contextual analysis; method of linguistic description – for direct study of the phenomenon in the text, systematization and generalization of adjectives of dimension translation features. The scientific novelty of the article is that, despite the significant achievements of domestic and foreign linguistics in the study of English adjectives of dimension, the problem of their field semantics with a fairly wide range of lexical compatibility still remains insufficiently studied. Therefore, this study highlights the problem of adequate translation and selection of a lexical equivalent from a wide range of synonyms that are part of the lexical and semantic group of adjectives of dimension. Also new is the research material – English-language films and their simultaneous interpretation, which we recorded in writing. Conclusions. Thus, adjectives of dimension of the micro field to denote the small overall size such as small, little, tiny, minute, microscopic, miniature, slight are translated in an appropriate way. Unlike other adjectives of dimension of the same micro field, small and tiny are used with a large number of comparative structures. Adjective of dimension small is often combined with collective nouns and words meaning representatives of flora and fauna. In contrast to the above- mentioned adjectives, adjective of dimension tiny has a wider range of equivalents, lexical and grammatical transformations are rarely used in its translation. In addition, the article identifies differences in the structures of the conceptual space of English adjectives of dimension to denote the general small size. Besides this, the basic stylistic and semantic differences between English adjectives of dimension that belong to the same micro field are established. The main methods and translation techniques of the adjectives of dimension to denote the general small size from English into Ukrainian and Russian are determined. The use of such lexical and grammatical transformations in translation as replacement of a word of one part of speech with a word of another (nominalization, adverbialization), lexical (contextual) replacement, semantic development, antonymous translation is mostly noticed.
Taras Shevchenko in the literary reception of Ivan Reboshapka
Authors: Markuliak Larysa
Published: November 2021

In the article the Shevchenko studies of the famous Romanian scientist-Ukrainist Ivan Reboshapka are analyzed. The scientific visions of the literary critic on the poetic universe of Taras Shevchenko are commented. The purpose of the article is to analyze the Shevchenko studies of the famous Romanian Ukrainianist, professor of the University of Bucharest Ivan Reboshapka, who makes up a large array of the scholar's literary studies. The relevance of the study is due to the need for a systematic analysis of the reception of T. Shevchenko's creativity in the literary discourse of a foreign scientist. The novelty of the article lies in the fact that there is no comprehensive analysis of T. Shevchenko's art in the assessment of the Romanian-Ukrainian scholar in contemporary Shevchenko studies. In the article biographical, descriptive and comparative research methods are used. Conclusions. Ivan Reboshapka's Shevchenko studios represent deep scientific observations at the intersection of cultural studies and literary studies. They are characterized by a multivector approach, a deepening into the individual style of the writer. Interdisciplinary parallels, many of which we observe in the literary works of Professor Ivan Reboshapka, are the basis for a modern rethinking of creativity of T. Shevchenko, and also offer the ways for further Shevchenko studies
IMPLEMENTASI MUSHÄ€RAKAH MUTANÄ€QIÅžAH WAL IJÄ€RAH DALAM PEMBIAYAAN HUNIAN SYARIAH PADA PT. BANK MUAMALAT INDONESIA CABANG PONOROGO
Authors: Sarpini Sarpini
Published: November 2021

The price of a house that is increasingly expensive makes not everyone can afford it because home is one of the basic needs for everyone. Bank Muamalat Indonesia has a financing product for the home namely is financing musyÄrakah mutanÄqiÅŸah  wal ijÄrah.
This research is both a descriptive analysis, i.e. the author lays out all the data that includes data about the reasons to use the musyÄrakah mutanÄqiÅŸah  wal ijÄrah in financing Residential Sharia in PT.Bank Muamalat Indonesia Branch Ponorogo. contract relationships and data on musyÄrakah mutanÄqiÅŸah and ijÄrah in financing Residential Sharia in PT.Bank Muamalat Indonesia Branch systematically Ponorogo, meticulous and factual with the deductive pattern i.e. a fringe theories or propositions that are common on musyÄrakah mutanÄqiÅŸah  then do an analysis of the data concerning multi contract to acquire a specific conclusion.This research concluded that the reason Bank Muamalat Indonesia branch using contract Ponorogo musyÄrakah mutanÄqiÅŸah  wal ijÄrah in financing the residence of Islamic Muamalat (PHSM) namely musyÄrakah mutanÄqiÅŸah  wal ijÄrah is suitable for contract be used as an alternative solution in financing PHSM in Bank Muamalat Indonesia branch Ponorogo.Bank Muamalat Indonesia branch using contract Ponorogo musyÄrakah mutanÄqiÅŸah  wal ijÄrah in financing the residence of Islamic Muamalat (PHSM) is reviewed from a multiple of contract that is allowed under Islamic law and does not include the category of the prohibition Hadith.The relationship contract musyÄrakah mutanÄqiÅŸah  and ijÄrah in Islamic Muamalat Residential Financing (PHSM) in Bank Muamalat Indonesia branch Ponorogo i.e. Shirkat al-' Belong ' (shared ownership) and ijÄrah.
RANCANG BANGUN PENGUATAN UMKM BERBASIS KULINER KHAS DAERAH MENUJU CIREBON HALAL TOURISM
Authors: Hasanudin Agus
Published: November 2021

Rancang bangun penguatan UMUKM berbasis kuliner khas daerah menuju Cirebon Halal Tourism. Penelitian ini bertujuan untuk mengidentifikasi dan menyusun strategi penguatan UMKM berbasis kuliner khas Cirebon dalam mengembangkan Halal tourism sertamenyusun model penguatan UMKM berbasis kuliner khas Cirebon dalam mengembangkan Halal tourism. Data yang digunakan dalam penelitian ini adalah yang diperoleh secara langsung melalui Focus Group Discussion (FGD) dan wawancara dari para narasumber yang terlibat dalam penelitian, yaitu dinas UMKM Kabupaten dan Kota Cirebon, dinas pariwisata Kabupaten dan Kota Cirebon, Perhimpunan UMKM Kabupaten dan Kota Cirebon, serta perwakilan UMKM Kabupaten dan Kota Cirebon. Hasil SWOT dari penilaian responden terhadap faktor internal didapatkan total skor rata-rata IFE sebesar 1.929. Hal ini mengindikasikan bahwa posisi strategi internal UMKM kuliner khas daerah Cirebon berada pada kondisi lemahsedangkanhasil dari penilaian responden terhadap faktor eksternal UMKM kuliner khas Cirebon didapatkan total skor rata-rata EFE sebesar 3.149. Hal ini mengindikasikan bahwa posisi external pada kondisi banyak peluang. Analisis matriks IE dengan hasil skor dari Matriks IFE sebesar 1,929 dan skor Matriks EFE sebesar 3,149, sehingga apabila masing-masing skor dipetakan kedalam Matriks IE maka posisi UMKM kuliner khas daerah Cirebon berada pada kuadran III. memiliki makna bahwa posisi ini menandakan sebuah organisasi yang lemah namun sangat berpeluang.Rekomendasi strategi yang diberikan adalah Ubah Strategi, artinya organisasi disarankan untuk mengubah strategi sebelumnya.Sebab, strategi yang lama dikhawatirkan sulit untuk dapat menangkap peluang yang ada sekaligus memperbaiki kinerja organisasi.
Joint Initiatives Instead of Multilateralism: A New Reality for the WTO?
Authors: Biryukova O. V.
Published: November 2021

The article examines the complexities of the negotiation function of the WTO, in which consensus in decision-making plays an important role. The author systematizes the possibilities and limitations for incorporating the results of plurilateral negotiations (i.e., with a limited number of participants) held within the framework of the so-called joint statement initiatives into the organization's law. The article also analyzes the prospects for integrating specific joint initiatives (internal regulation in services, simplification of investments in development, e-commerce) into the WTO system. The article emphasizes that despite standard features, all initiatives are unique in their content, format, and history and are at different stages of readiness, for Russia, which takes an active part in these joint initiatives, bringing the negotiations to a conclusion. The article criticizes joint initiatives from their primary opponents (India and South Africa), who insist that plurilateral initiatives' participation ignores existing multilateral mandates reached by consensus. Thus, they destroy the multilateral system.The purpose of the article is to review conceptual and practical approaches to forming new trade rules in the WTO system in the context of the multilateral crisis. The author concludes that plurilateral agreements can become a way out of the crisis in the negotiation function of the WTO, as well as the basis for future trade agreements in the system of organization. However, for plurilateralism to be effective and sustainable, it must be linked to multilateral norms and principles. Any plurilateral approach must allow flexibility in forming the basis for negotiating trade rules at multilateral level. It seems that if in the near future the WTO does not take decisive actions to adjust the rules and procedures for the new agreements, the prospects for advancing negotiations and maintaining the relevance of the leading institution of the international trading system will become even bleaker.
Awareness and knowledge about painconcepts among medical students in King Abdulaziz University: a cross-section study
Authors: Trabulsi Nora , Alzahrani Abdulmajeed , Khafagy Abdulmajeed , Banaamah Mohanned , Alazdi Fawaz , Safhi Mohammed , Saleem Abdulaziz , Kadi Mai , Nassif Mohammed , Samkari Ali
Published: November 2021

Background: Pain is a common presenting complain in general practice and constitutes a major proportion of outpatient visits. This study aimed to assess clinical medical students\' knowledge and awareness regarding pain concepts at King Abdulaziz University (KAU).
Methods: A cross-sectional study was conducted using a questionnaire administered through an online survey form among medical students of KAU. The questionnaire contained baseline characteristics of students and open and closed-ended items related to awareness and knowledge regarding pain concepts.
Results: The study showed that 63.8% of medical students reported attending lectures on pain management, and among those, 55.6% received that within the medical curricula. It was found that 19.2% reported that they educated patients suffering from acute/chronic pain. Only 17% students demonstrated good knowledge regarding pain concepts. The knowledge level of the students showed a significant relationship with grade point average and clinical interest of the students (p < 0.05).
Conclusion: The study demonstrated a deficiency in knowledge and exposure regarding pain concepts and their management. Undergraduate medical curricula should be reassessed in that aspect to provide adequate training in pain management.