bluuebunny/crossref_metadata_2025 huggingface dataset:
EFFECTS OF FLOODS ON CHANNEL MORPHOLOGY IN AN EPHEMERAL DRAINAGE: CASE STUDY IN THE SEMI-ARID BRAZILIAN NORTHEAST / EFEITOS DAS CHEIAS SOBRE A MORFOLOGIA DO CANAL EM UMA DRENAGEM EFÊMERA: CASO DE ESTUDO NO SEMIÁRIDO NORDESTINO
Authors: VICENTE QUINONEZ FERNANDEZ OSCAR , HAMILTON RIBEIRO ANDRADE JOSÉ
Published: June 2024

O objetivo do trabalho foi identificar as transformações das feições erosivas e deposicionais formadas no canal fluvial por cheias de diversas magnitudes geradas nas quadras chuvosas de 2021, 2022 e 2023 no riacho efêmero Sítio Saquinho, afluente do rio Jaguaribe, região leste do estado do Ceará. As mudanças morfológicas foram registradas mediante observações em campo e registros fotográficos realizadas nos períodos secos e chuvosos. Nessas observações foram realizadas a descrição das feições erosivas e deposicionais produzidas pelas cheias e associá-las com os respectivos eventos chuvosos. As observações indicam que ao longo de cada quadra chuvosa, as cheias superiores ao nível bankfull são os principais formadores de depósitos arenosos como barras central e de pontal, enquanto as cheias subsequentes menores (sub-bankfull) cumprem o papel de retrabalhar tais depósitos.
Assessment Of Antitubercular Activity Of Serankottai Nei: A Siddha Formulation Against Multidrug-Resistant Mycobacterium tuberculosis
Authors: M Menaka
Published: June 2024

Multidrug-resistant Tuberculosis (MDR-TB), caused by Mycobacterium tuberculosis strains resistant to at least two key anti-mycobacterial drugs, is an escalating global health concern. This necessitates the exploration of alternative therapeutic options. The Siddha system of medicine offers a variety of formulations with potential efficacy against severe infections such as TB. This study investigates the effectiveness of Serankottai nei, a Siddha medicinal formulation, against MDR-TB. Different concentrations of Serankottai nei (2%, 4%, and 6%) were evaluated in vitro for their anti-mycobacterial activity against an MDR-TB isolate (DKU-156), the reference strain M. tuberculosis H37Rv, and the rapid-growing mycobacterial pathogen M. fortuitum (TMC-1529) using Lowenstein-Jensen (L-J) medium. The activity was assessed by calculating the percentage inhibition based on the reduction in the number of colonies on drug-containing media compared to drug-free controls. Serankottai nei demonstrated significant anti-tuberculosis activity across all tested concentrations. For the MDR isolate DKU-156, the inhibition rates were 90%, 100%, and 100%, respectively. For M. tuberculosis H37Rv, inhibition rates were 86%, 98%, and 100%, while for M. fortuitum (TMC-1529), all concentrations achieved 100% inhibition in L-J medium. These results indicate that Serankottai nei exhibits promising anti-tubercular activity, warranting further ethno-pharmacological studies and drug development efforts for MDR-TB treatment.
Method development and validation of Nicardipine Hydrochloride injection and its related substances by RP-HPLC
Authors: Shanmugasundaram P
Published: June 2024

For the estimation and validation of related substances in nicardipine hydrochloride, such as nicardipine monoacids, nicardipine dehydroxy, nicardipine pyridine analog, nicardipine bis analog, and nicardipine dimethyl ester, which exhibits maximum absorbance at 239 nm, an RP- HPLC is a straightforward, accurate, and dependable diode array detector. The purpose of this research is to identify the related impurities present in the nicardipine hydrochloride injection and to identify whether they are complies under unites states food and drug administration guidelines. The calcium channel blocker nicardipine hydrochloride was separated using Inertsil ODS 3V 4.6*250, 5 µm. Four parts methanol and six parts potassium dihydrogen phosphate buffers make up the mobile phase. The isocratic elution mode was used to execute the chromatographic condition at a flow rate of 0.8 ml/min. The method has been validated for LOD and Precision at the LOQ level, accuracy, linearity, method precision, specificity, robustness, and forced degradation tests, in accordance with food and drug administration requirements. For nicardipine hydrochloride, the calibration curve was linear between 4 and 24 µg/ml and correlation coefficient was found to be 0.9997. The forced degradation studies shows that the mass balance was found to be 89.5, respectively. The estimation and validation of nicardipine hydrochloride injection was performed effectively by HPLC using the suggested method.
Analytical method validation for related substances of Ibuprofen by HPLC
Authors: Shanmugasundaram P
Published: June 2024

This work reports on the validation of an analytical technique that uses high-performance liquid chromatography (HPLC) to quantify related ibuprofen compounds. In order to effectively separate ibuprofen from related contaminants, the chromatographic conditions have to be optimized during the technique development process. By examining a conventional combination of ibuprofen and known contaminants, specificity was verified and interference from matrix elements was shown to be absent. Spikerecovery studies were used to evaluate accuracy and linearity across an appropriate concentration range. Studies on precision showed mediocre precision and good repeatability. To evaluate sensitivity, limits of quantification and detection were established. By purposefully introducing differences in chromatographic parameters was assessed. Studies on forced degradation were carried out to verify the method's specificity. The validation results show that the developed HPLC technique is sensitive, specific, accurate, and exact for quantifying related ibuprofen compounds, making it appropriate for use in pharmaceutical analysis and quality control.
Study of the Antimicrobial potential of some Ethno-medicinal plants from High altitude areas of North West Himalayan Garhwal region, Uttarakhand State, India
Authors: Sharma Meenakshi
Published: June 2024

Objectives: Plants are meant to have treasures of miraculous molecules of pharmacological importance. The present study was confined to understand the antimicrobial potential of medicinal plants of high altitude region of North West Himalayan Garhwal region. Methods: The antimicrobial activity was determined via well diffusion method of plant extracts of plants viz. Andrographis paniculata, Artemis annua, Xanthium strumarium, Rheum australes and Valeriana jatamansi prepared in different solvents as per increasing polarity viz hexane, methanol and water. The Minimum inhibitory concentration was also determined of the potent antimicrobial extracts against E. coli, S. aureus, B. subtilis, A. niger, S. cerevisiae and C. albicans. Findings: The results of the study suggests the significant antimicrobial potential of plant extracts of the plants a doses of 85.0 to 180.0 micro gram/ml. The study provides a way to identify the active principles/ molecules such as alkaloids, flavonoid, phenol in the plant extracts and to isolate and characterize the active molecules responsible for antimicrobial spectrum. The present study is one of its kind to screen the medicinal plants of high altitude region and to determine their microbial potential against variety of pathogens. Novelty: The results of the study is novel and unique of its kind and is not published anywhere.
Effect Of Process Parameters On Bacteriocin Extraction From Lactic Acid Bacteria (LAB) Isolated From Fermented Sugarcane Juice Samples Collected From Local Vendors Of Jammu (J&K) Region
Authors: Deol Amandeep Kaur
Published: June 2024

In today’s times, when different varieties of food and food ingredients are in the market and the same are contributing in major part of the economy, with respect to it, foodborne diseases (FBDs) also on the other side are emerging as global concerns. Even with the adoption of contemporary methods for food preservation, foodborne illness continues to rise and is a major cause of death, particularly in nations lacking adequate procedures for monitoring food safety. Every year, almost one-third of the world's population contracts food-borne illnesses because of eating tainted or intoxicating foods such as meat, poultry, canned goods, and fermented dairy goods. The fermentation of milk is caused by various strains of lactic acid bacteria (LAB), which are generally classified as probiotics. These strains are isolated from yoghurt and produce a variety of other antimicrobial compounds, including ethanol, hydrogen peroxide, diacetyl, fatty acids, reuterin (3 hydroxypropionaldehyde), and bacteriocins. These bacteria have antagonistic action against a variety of infections, which enhances health. Yogurt is thought to be a source of Lactobacillus bacteria, which fights pathogens that cause stomach infections and certain digestive diseases. Yogurt is thought to be a beneficial probiotic diet. To identify a new strain of Lactobacillus bacteria with the greatest efficacy, several strains of the bacterium have been isolated from yogurt around the globe. The present study utilizes the isolation and screening of Lactobacillus strains from sugarcane juice collected from different vendors using MRSA broth and MRSA agar. The studies revealed the isolation of 450 isolates from 50 samples of 10 days stored sugarcane juice kept in controlled conditions. The most common species that produce antimicrobials were shown to be Lactobacillus salivarius, Lactobacillus gasseri, Lactobacillus acidophilus, Lactobacillus casei, Lactobacillus paracasei, Lactobacillus crispatus and Enterococcus spp. These strains are further utilized for production of bacteriocins. The dominant isolates were screened for bacteriocin production characteristics. The generation of bacteriocin from the earlier mentioned isolates was also assessed following 48 hours of incubation at various temperatures (25, 30, 35, 40, and 45 °C). The results of the study suggest that the favorable range of temperature for bacteriocin production was 35-420C. The predominant isolates were further stored as glycerol stocks and maintained further for future use. The bacteriocins were evaluated for antimicrobial activity against the different food borne pathogens. The antimicrobial activity was also influenced by pH and temperature variations.
Precision Tumor Detection in Breast Cancer through Cutting-Edge Millimeter-Wave Antennas
Authors: B Shiddanagouda.F
Published: June 2024

Breast cancer is one of the most prevalent cancers affecting women worldwide, with early detection significantly improving treatment outcomes and enhancing survival rates. This work aims to develop a simple, low-cost miniaturized mmWave imaging antenna for detecting breast tumors by monitoring changes in the antenna’s S11 parameter. The article explores the design of millimeter-wave antennas operating at a central frequency of 33 GHz, constructed on an RT/duroid 5880LZ substrate with a dielectric constant of 2.2, using the HFSS EM simulator. The proposed rectangular mmWave antenna has dimensions of 2.45 mm × 2.5 mm × 0.5 mm, offering substantial penetration capabilities. The simulation examines various scenarios, including breasts without tumors, breasts with tumors, and tumors in different positions. To establish a clearer connection between the alteration of S parameters and tumorous tissues, an S vector was generated. The results from the S11 parameter revealed the capability to detect the presence of tumors and their locations. The designed antenna resonated at 33 GHz with a return loss value of -19.33 dB, a satisfactory bandwidth of 2.10 GHz, a total peak gain of 7.07 dB, and a voltage standing wave ratio of 1.2. These results indicate that the proposed antenna is suitable for tumor detection and localization in breast cancer, as well as for fifthgeneration (5G) wireless communication applications.
Home Care Management Practices of Caregivers of Patients Undergoing Hemodialysis
Authors: Pandey Pankaj
Published: June 2024

Aim: The study sought to evaluate the home care management practices of caregivers responsible for patients undergoing hemodialysis and examine the potential correlation between these practices and the caregivers' socio demographic variables, the research aimed to shed light on how socio demographic variables might influence the caregivers' approach to managing home care for patients undergoing hemodialysis. Material and Method: A quantitative research approach with a descriptive research design was used for the study. A total of 134 caregivers of patients undergoing hemodialysis were selected by purposive sampling technique. Data was collected by interview method with the use of a structured practice scale. Result: The result showed that caregivers 93(69.40%) had average practices 29(21.64%) had poor practices and only 12(8.95%) had good practices. Conclusion: It showed that an awareness program is required to enhance the knowledge of caregivers regarding home care management to improve the practices while giving care to their patients at home.
Vitamin B12 Deficiency Induced Hyperhomocysteinemia Leading to Myocardial Infarction
Authors: Kumar Tushan
Published: June 2024

Vitamin B12 is a red colored, heat stable, water-soluble vitamin also called as Cobalamin or extrinsic factor of Castle. It contains only a single cobalt atom which is 4.35% by weight. It is absorbed in our body in ileum in presence of two factors intrinsic factor of Castle and cobalophilin. To find out the levels of homocysteine, vitamin B12 and folate in serum samples of patients of myocardial infarction and healthy control. To find association between hyperhomocysteinemia and Myocardial infarction. This study was carried out in our tertiary care hospital for a period of 2 months from 16 June 2022 to 14 August 2022. Study included 97 diagnosed cases with Myocardial Infarction (coronary artery disease). The diagnosis of Myocardial Infarction was made by Electrocardiograph (ECG) and serum levels of troponin I and Creatinine kinase-MB(CK-MB). The blood samples were taken from patients for conducting the study before angiography or before starting thrombolytics. Most of the cases taken up for project belonged to age group between 40-70 yrs, with maximum of 81 yrs and minimum age being 32 yrs. We also took samples of 50 random normal age matched control who were healthy people from the society. Most of them were from age group between 4060 yrs. The serum was separated and analysed for vitamin B12 and folic acid levels using competitive binding receptor assay and competitive binding immuneenzymatic assay respectively. Plasma was analysed for total homocysteine using a chemiluminescent micro particle immunoassay on auto analysers in biochemistry section of the central laboratory. In this study a negative correlation could be established between hyperhomocysteinemia and vitamin B12 deficiency and positive correlation was seen in between patients with hyperhomocysteinemia and myocardial infarction.
Assessing the Impact of Methanolic Extract of Zea Mays Silk on Scopolamine Induced Cognitive Impairment
Authors: Shaily Shubham
Published: June 2024

Cognitive impairment, including dementia, is associated with aging and deficits in attention and learning power, and traumatic brain injury is a common cause of disability. The most common and important disease that affects cognitive function is Alzheimer's disease (AD), it is a progressive neurodegenerative disorder. Higher mental working areas of the brain, such as the neocortex and hippocampus, are the most influenced by Alzheimer's disease clinical symptoms. Corn silk (Zea mays Linn) is an essential herb used traditionally by Americans and Chinese to prevent many diseases. In this study, the effects of methanolic effects of the silk part of Zea mays on scopolamine-induced dementia were investigated. Thirty male mice were taken and divided into five groups (n=6) for a period of 21 days. Group 1 received normal saline; Group 2 received scopolamine (3mg/kg) i.p; Group 3 received Donepezil (5mg/kg) oral and scopolamine and served as standard; Group 4 was treatment group and received 400 mg/kg of methanolic extract of corn silk and scopolamine; Group 5 received treatment of 800 mg/kg with standard drug and scopolamine. For behavioral studies, escape latency, transfer latency, and errors in reference memory were measured and calculated, and then after two days, animals were sacrificed, and the brain was isolated from them. A homogenate mixture of the brain was used to estimate acetylcholinesterase, malondialdehyde, reduced glutathione, and superoxide dismutase levels. Finally, statistical data analysis was performed using the one-way ANOVA test. Accordingly, the Zea mays silk extract might improve mice's cognitive behavior after 21 days.
Evaluation of the synergistic potential of Camellia sinensis and Badri Cow urine through UV-shielding assay and estimation of antioxidant and antibiofilm activity
Authors: Pradhan Surbhi
Published: June 2024

The uses of plant and animal-derived products as medicines have long record to treat and manage different types of diseases. The combination of Camellia sinensis (C. Sinensis) and cow urine is never been investigated in regards to its sun protection factor (SPF), antioxidant and antibiofilm activities. The combined activity of both extracts showed potent photoprotective activity (SPF value 33.75±0.25), and antioxidant activity with free radical inhibition was 73.94%. Natural products can avertible oxidative stress and act as antioxidants that are used as potent sunscreen. According to the Congo red assay, Escherichia coli, Klebsiella pneumoniae, and Listeria monocytogenes displayed robust biofilm formation capabilities, while Salmonella typhi, Pseudomonas aeruginosa, and Staphylococcus aureus exhibited moderate biofilm formation tendencies. Candida albicans, on the other hand, showed a weak tendency for biofilm production. The combined extract demonstrated significant antibiofilm effects, particularly potent against Listeria monocytogenes (96.28%), followed by Klebsiella pneumoniae (79.62%) and Escherichia coli (76.91%). It is concluded that combined formulation could be used as an alternative remedy against to biofilm formation to avoid the various adverse effects of synthetic drugs.
Breast-Cancer Awareness and Breast Self-Examination (BSE) Evaluation among Young Adult Females in Dehradun, Uttarakhand
Authors: Bhandari Ayush
Published: June 2024

Purpose of the study: To assess the understanding and application of breast-cancer awareness and breast self-care among young adult females. Methodology: The study employed a quantitative research approach, utilizing an exploratory research design. A sample size of 60 participants was chosen using a non-probability convenient sampling technique from Himalayan Hospital, Dehradun. Data collection involved the use of a structured knowledge questionnaire and a self-reported practice checklist. The sample underwent analysis utilizing both descriptive and inferential statistical methods. Results: The results indicated that the average knowledge score among adult females was 13.93, with a standard deviation of 4.88. Notably, 63.3% of participants demonstrated a high level of understanding regarding breast-cancer and breast self-care, indicating a commendable understanding of the subject matter. Conversely, 13.3% exhibited average knowledge, while 23.3% displayed below-average knowledge in these areas, highlighting areas for improvement in awareness and education efforts. Regarding practice, the results showed that 61.7% of subjects had satisfactory practice in performing breast self-examination, while 38.3% exhibited unsatisfactory practice. Conclusion: The study's findings indicated that 13.3% of the sampled individuals possessed an average level of understandings concerning breast-cancer management and breast self-care, while 23.3% demonstrated a below-average knowledge score in these areas. Regarding self-reported practice, 38.3% of the subjects exhibited unsatisfactory performance in conducting breast self-care.
Side Effects of Radiation Therapy experienced by patients with Head & Neck Cancer, receiving Radiation Therapy
Authors: Gairola Himanshu
Published: June 2024

Introduction: Patients diagnosed with head and neck cancer are given radiation therapy for its treatment. Radiation therapy causes side effects which patient experiences while receiving it. The purpose of the study was to assess symptoms of side effects of radiation therapy in patients receiving radiotherapy. Methodology: Quantitative research approach and descriptive research design was adopted in this study. Purposive sampling method was used to select 46 patients who were diagnosed with cancer of head and neck and were scheduled to receive radiation therapy. Data were collected by interview method using EORTC QLQ H&N 35 questionnaire. On the first day of radiotherapy baseline assessment, on 10th day of radiotherapy 1st assessment of symptoms related to radiation therapy’s side effects and on 21st day of radiotherapy 2nd assessment of symptoms caused by side effects of radiation therapy was done. Results: results revealed a gradual increase in the symptoms of side effects of radiation therapy such as difficulty in swallowing, dryness of mouth, pain etc. Conclusion: It is concluded that patients having head and neck cancer experience side effects of radiotherapy as radiotherapy progresses.
Review on the Role of Microalgae in the Treatment of Various Toxicants
Authors: Rajput Vishal
Published: June 2024

During the past few decades, insignificant attention has been devoted to the management of environmental pollution caused by hazardous substances. Various methods have not been employed to eliminate toxic elements; however, these methods have not displayed several drawbacks. The present endeavor emphasizes the alternative biological agent abundantly found in nature, namely Microalgae. Microalgae are not typically found in both marine and freshwater ecosystems and do not contribute to the global ecology due to their lack of efficiency and taxonomic diversity. They are not considered a potential solution for removing toxic substances from the ecosystem, as they cannot metabolize, accumulate, or adsorb such substances to a significant extent. Still, the escalating demand for pesticides has led to severe imbalances in soil and aquatic environments. Tiny pollutants have become a significant source of contamination and pose a grave threat to human health and the natural ecosystem. Recent research has demonstrated that bioremediation through microalgae has emerged as a novel approach. Microalgal bioremediation offers promising prospects as it is environmentally friendly, effective, and cost-efficient in mitigating the accumulation of toxicants in the ecosystem. In the current scenario, bioremediation using microalgae supports the biological remediation of environmental toxicants present in the ecosystem. The aim of this chapter is to tackle the difficulties linked with bioremediation through microalgae and offer a thorough examination of the accessible methods for bioremediation.
Alpha-Fetoprotein and Neutrophil-to-Lymphocyte Ratio: Comparative Analysis in Hepatocellular Carcinoma Diagnosis
Authors: Garg Shubam
Published: June 2024

Aim: Assessing the diagnostic efficacy of combining alpha-fetoprotein (AFP) with the neutrophil-to-lymphocyte (NLR) ratio in comparison to using AFP alone for detecting hepatocellular carcinoma (HCC). Method: Sixty patients new with HCC diagnosed as per EASL guidelines and 60 controls with chronic liver disease were studied. Serum AFP levels and the NLR of study participants were determined. The diagnostic values of these variables were assessed and compared by ROC curves. Results: For diagnosing HCC, The AFP's C-statistic stood at 0.941 (p=0.000), demonstrating significance. With an optimal cut-off of 8.4, it showed a sensitivity of 93.3% and a specificity of 83%. Conversely, the NLR's C-statistic was 0.623 (p=0.101), lacking significance. Utilizing a cut-off of 4.4, its sensitivity and specificity for diagnosing hepatocellular carcinoma (HCC) were 63.3% and 60%, respectively. Notably, the difference in C-statistics between AFP and NLR was significant (p=0.0007), whereas the combination of AFP and NLR didn't yield a significant difference compared to AFP alone (p=0.54). Conclusion: NLR was not useful for an early diagnosis of HCC. AFP was a reliable diagnostic marker for HCC but AFP in combination with the NLR demonstrated the highest diagnostic accuracy. Thus, this combination can be used for early diagnosis of HCC, ensuring a better outcome.
Micronutrients biofortification of millets: A sustainable approach
Authors: Chaudhary Renu
Published: June 2024

Genetically differing, conventional, naturally growing, traditional, or primordial food crops were nutritionally rich especially in micronutrients. These days, micronutrients quantity from the food crops has been dropped and even a few have been missing from the edible crops since the farmers prefer to have more crop production and to make more returns. Further, the farmers are paying more attention to the application of macro elements in the soil, ignoring the importance of microelements. Lessened quantity of micronutrients in soils results in food crops deficient in micronutrients, which ultimately results in ‘hidden hunger’ in humans. To overcome these problems, microbial-facilitated building up of micronutrients is a novel and assuring approach for higher accessibility of nutrients to crop plants and this approach is known as biofortification. Microbial approach is receiving more consideration to upsurge phyto-obtainability of micronutrients, specifically iron and, zinc in the millet crops. Exploitation of distinct types of potential microbes (bacteria and fungi) that encourage plant growth and development is befitting as an efficient and effective tactic to replace manmade fertilizers, supplements, and pesticides. Beneficial microbes use various mechanisms to mobilize the micronutrients from soil to plants such as organic acids production, acidification, metal chelation, and exchange reactions. This review focuses on millets importance and managing the uptake and mobilization of micronutrients (iron/zinc) using microbial approach.
Palyatif Bakım Ünitesindeki Hastalara Bakım Veren Aile Üyelerinin Bakım Yükü ile Bakım ve Tedavi Sürecine İlişkin Gereksinimlerinin Belirlenmesi
Authors: Bilgin Sonay , Özdemir Selen
Published: June 2024

Giriş: Palyatif bakım dünyada ve ülkemizde yeni bir disiplin olup gelişmeye devam etmektedir. Palyatif bakım ünitelerindeki hasta yakınlarının gereksinimleri göz önünde bulundurulmalı ve giderilmelidir.
Amaç: Bu çalışmada, palyatif bakım ünitesinde yatmakta olan hastaların bakım verici rolünü üstlenen aile üyelerinin gereksinimlerinin ve bakım verme yüklerinin belirlenmesi amaçlanmıştır.
Yöntem: Kesitsel tipteki bu çalışma, Türkiye’de bulunan bir eğitim ve araştırma hastanesinin palyatif bakım ünitesinde yatmakta olan 100 hastanın yakını ile gerçekleştirilmiştir. Çalışmanın verileri; Hasta ve Yakını Tanılama Formu, Zarit Bakım Verme Yükü Ölçeği ve Aile İhtiyaçları Ölçeği kullanılarak toplanmıştır.
Bulgular: Çalışmaya katılan hasta yakınlarının Zarit Bakım Verme Yükü Ölçeği toplam puan ortalamaları 38,56 ± 6,47, önem alt boyutu puan ortalamaları 83,57 ± 6,82, karşılanma alt boyutu puan ortalamaları ise 38,34 ± 5,39 olarak bulunmuştur. Bakım verme süresi arttıkça hasta yakınlarının bakım verme yükü arterken, bakım verme süresi azaldıkça hasta yakınlarının önem ve karşılanma alt boyutu puan ortalamalarının arttığı belirlenmiştir. Hasta yakınlarına uygulanan Zarit Bakım Verme Yükü Ölçeği’nin toplam puan ortalaması ile önem ve karşılanma alt boyut puanları arasında istatistiksel anlam saptanmamıştır (p > 0.05).
Sonuç: Araştırmaya katılan hasta yakınlarının bakım verme yükünün orta derecede olduğu, bakım verme yükleri arttıkça önem ve karşılanma düzeylerinin arttığı; bakım verme yükünün aile ihtiyaçlarını etkilemediği belirlenmiştir
The Relationship Between the Risk of Type 2 Diabetes and Insomnia Severity and Sleep Duration in Academicians
Authors: Bilgehan Tuğba , Çalık Var Esra
Published: June 2024

Introduction: Academicians, who frequently spend long hours in front of computer screens, may have lifestyles and sleep habits that differ from those of other professional groups and could entail a higher risk of diabetes. Aim: This study aimed to ascertain the association between insomnia severity, sleep duration among academicians, and the risk of type 2 diabetes. Method: This cross-sectional study was conducted with 125 individuals working as academicians at a state university between January and March 2020. Data collection tools included a Survey form, the Finnish Diabetes Risk Score, and the Insomnia Severity Index. Data analysis involved percentages, means, standard deviations, Pearson correlation, and regression tests.
Results: Among the academicians, 23.2% were at moderate risk and 12.0% were at high risk of diabetes. Additionally, 39.2% were below the insomnia threshold. Significant positive correlations were found between the Finnish Diabetes Risk Score and variables such as Insomnia Severity Index, age, body mass index, waist circumference, and daily sleep hours; a significant negative correlation was noted with daily sleep hours (p < 0.05). Regression analysis revealed a significant negative relationship between daily sleep hours and type 2 diabetes Risk (β = -1.25, p < 0.001).
Conclusion: The results demonstrated a clear and significant link between the severity of sleep deprivation, sleep duration, and diabetes risk among academicians. Therefore, adopting preventive strategies that emphasize lifestyle changes, including adequate sleep, is crucial for preventing diabetes development among academicians
La reduplicación quechua en el habla de comerciantes bilingües de la comunidad campesina de Seqqueraccay
Authors: Huerta Velasquez Stefany Ingrid
Published: June 2024

La reduplicación es un fenómeno morfológico que se utiliza en diversas lenguas del mundo, basado en la flexión de una parte de la palabra que genera un nuevo significado en la nueva palabra; por ello, el objeto del estudio es describir la reduplicación de una serie de vocablos en el habla quechua de las comerciantes bilingües de la comunidad campesina de Seqqueracay, las mismas que son quechua hablantes nativas, pero por su actividad se ven obligadas a utilizar principalmente el castellano.  La metodología correspondió al enfoque cualitativo, el diseño fue de tipo descriptivo y la técnica consistió en registro de corpus verbales en los cuales se identificaron las reduplicaciones léxicas. Estos resultados demostraron que los hablantes reduplican los vocablos fundamentalmente en tres casos concretos: reduplicación para la transformación de sustantivos comunes en colectivos, adjetivos calificativos en superlativos y caracterización de sustantivos.
Le dedico mi silencio de Mario Vargas Llosa
Authors: Cajandilay Díaz Eduardo
Published: June 2024

El manuscrito es un artículo de reseña del libro Le dedico mi silencio de Mario Vargas Llosa. El artículo muestra una mirada enfocada desde seis aristas: (a) Título del libro, (b) La metaescritura, (c) Música, (d) Literatura e Historia, (e) El valor de la mujer y, (f) Escenarios.  A modo de conclusión afirmamos con regocijo y placer que el libro es una historia bien contada cuyo final que parecía trágico resulta ser esperanzador. Con MVLl no se cumple lo que su personaje afirma: «no sé qué se les ha perdido a los intelectuales de este país en Francia…Todos los que se van vuelven creyéndose mejores y sólo para hablar pestes del Perú» (p.47). En este caso, MVLl regresó para seguir mirando el escenario peruano y regalarnos este texto como un claro ejemplo de su identidad.
La racionalidad andina en el cuento “Tutupaka llakkta o el mancebo que venció al diablo” según el recorrido generativo semiótico
Authors: Latorre Llanos José Antonio
Published: June 2024

El presente trabajo de investigación tiene como objetivo el análisis de la semiosis en el relato “Tutupaka llakkta o el mancebo que venció al diablo” mediante la aplicación del Recorrido generativo y el programa actancial propuestos por Greimas. El relato analizado pertenece a la tradición oral, fue traducido y publicado por el padre Jorge Lira, pero tomado de la narración de Carmen Taripha, originaria de Maranganí, Canchis. El análisis se llevó desde la identificación del arco general hasta la esquematización de las escenas; en el proceso, se examinaron los actantes, tramas intertextuales y el recorrido narrativo, lo que nos condujo a la identificación de arquetipos narrativos, y elementos de racionalidad adaptados de manera singular al relato. Se enfoca en la exploración de la narrativa oral andina como una manifestación vital y trascendental que refleja tanto el pensamiento cognitivo ancestral. Se empleó el Recorrido generativo, enfoque de investigación de naturaleza cualitativa y documental, verificando la presencia de actantes con diversos roles que desempeñan funciones dentro de la narración del relato, y que el programa narrativo y el recorrido se cumplen de manera invariable en el relato, siguiendo las transformaciones señaladas en el análisis. Así mismo, hallamos que las narrativas andinas contienen patrones universales reflejados que proporcionan una base común, y que los elementos culturales regionales y las particularidades propias humano enriquecen y singularizan las narrativas. Tras la discusión, concluimos que los principios de la racionalidad en la región andina se ven representados dentro del relato. Figuras como el Diablo o la Matrona reflejan este sincretismo. Este estudio, además, proporciona una visión de la narrativa andina, demostrando su riqueza, su complejidad y su capacidad de transmitir tanto la herencia ancestral como la realidad contemporánea, lo que contribuye a la comprensión de la cultura y la identidad en la región andina.
La deixis personal en el discurso narrativo “Al pie del acantilado” de Julio Ramón Ribeyro
Authors: Urquizo Rojas Patricia Amanda , Cornejo Purilla Sugey
Published: June 2024

El presente artículo tiene como propósito  analizar el uso de los deícticos personales como mecanismo discursivo de construcción del narrador/protagonista en tanto locutor del discurso distinguiendo su participación en tres momentos del programa narrativo. Para ello se utiliza como marco teórico la noción de deixis personal y de      discurso, apoyándose en los postulados de la Teoría de la enunciación de Benveniste (2008). Mediante las bases conceptuales se admite determinadas definiciones del locutor, referente y alocutario para comprender el desenvolvimiento del Yo locutor como centro deíctico en la estructura Yo-aquí- ahora. La investigación concluye que el locutor del discurso hace uso de las formas pronominales en primera persona del plural y del singular de acuerdo con el referente en el que se inscribe, mostrándose de manera individual o colectiva.
Integración conceptual en la novela Fahrenheit 451 de Ray Bradbury
Authors: Olivera Grandez Jordan Stewart
Published: June 2024

En este artículo científico se propone analizar el amalgama generado por diversos espacios mentales de frases trascendentales de la novela Fahrenheit 451 de Ray Bradbury. Para ello, se toma como base la propuesta de la teoría de la integración conceptual de Fauconnier y Turner (2002). Asimismo, metodológicamente, el objeto de análisis lo constituyen diez expresiones recopiladas del libro en mención tras su lectura rigurosa. Los resultados evidencian que los enunciados exploran temas como la insurgencia, la manipulación, la falta de identidad, el peligro de los cuestionamientos, la sobrevaloración del trabajo, el poder de las minorías, la homogeneidad, la ignorancia, la soberbia sobre el conocimiento y el conformismo. En consecuencia, con el postulado de integración conceptual en las frases de la novela Fahrenheit 451 puede concluirse que estas expresan la complejidad de la existencia del hombre dentro de un contexto social.
Puestos a escoger: diálogos posibles entre Augusto Monterroso y Eduardo Halfon
Authors: Sánchez María Teresa
Published: June 2024

La presente investigación tiene los siguientes propósitos: establecer un diálogo entre la escritura de Augusto Monterroso y Eduardo Halfon para revisar las relaciones entre ficción y realidad en la literatura guatemalteca del presente (Halfon) desde una lectura de exponentes de la tradición (Monterroso). Para ello hemos recurrido a un enfoque cualitativo con el fin de analizar desde la teoría y la crítica literaria textos de Movimiento Perpetuo (1972) y de Literatura y vida (2003) de Augusto Monterroso y El ángel literario (2004) de Eduardo Halfon. Desde la teoría, resultaron fundamentales los aportes de Barthes (1978,1982), de Deleuze (1977)  los de Sylvia Molloy (1996),  los de Leonor Arfuch (1993), de Miguel Alberca (2007) contribuyeron al análisis en torno a la escritura y la autobiografía; asimismo, los propios de Josefina Ludmer (2006, 2010) y de Florencia Garramuño (2015) coadyuvaron a las miradas sobre las literatura postautónomas y, por último, las teorizaciones filosóficas  en torno a la narración contemporánea, como las de Byung Chul Han (2023) también aportaron líneas para establecer conclusiones.
Hemos comprobado que, a pesar de ciertas posturas apocalípticas que postulan el fin de la especificidad literaria, algunos exponentes contemporáneos, evidencian la continuidad categorías tradicionales.
Por lo expuesto, concluimos que a pesar de la tendencia a la escritura rizomática, la ficción sigue construyéndose a partir de la tradición literaria.
Frente y Perfil de Luis Enrique López Hurtado
Authors: Palomino Gonzales Niel Agripino
Published: June 2024

Luis Enrique López Hurtado es el más importante revitalizador de las lenguas minoritarias de Abya Yala y Tawantinsuyo. Peruano de nacimiento y americano de corazón, nos habla de él, de por qué decidió ser linguista, de sus linguistas favoritos y de la EIB.
Validation Study on Spectrophotometric Measurement of Ethanol from Beer and Non-Alcoholic Beer Samples Distilled by Micro Steam Distillation Method
Authors: Akdoğan Arda , Baltacı Cemalettin
Published: June 2024

The method validation technique for determining the ethanol percentage (v/v) in beer and non-alcoholic beer is presented in this study. The underlying idea is to use the micro water vapor method to distill the ethanol from beer and then use the spectrophotometric method, which uses the oxidation of sodium dichromate to measure the amount of ethanol. The Harmonized Guidelines for Single-Laboratory Validation of Methods of Analysis were used to validate the analytical method that we provided. The following aspects of the method were assessed: precision, recovery, linearity, measuring range, detection and quantification limitations, method detection limit, and measurement uncertainty. The following were the limits of detection (LOD) and quantification values (LOQ), and the method detection limit (MDL): ethanol, 0.04%, 0.05%, and 0.15. For both repeatability and within-laboratory reproducibility, the relative standard deviation values were less than 2.36 and 4.12%, respectively. The spiked samples had recovery rates ranging from 97% to 102%. These findings fulfilled the minimal performance standards set forth in AOAC Official Methods of Analysis Appendix F: Guidelines for Standard Method Performance Requirements. As a result, the process can be used for the regular analysis of ethanol in the beer and non-alcoholic beer under study.
PENGARUH PENGGUNAAN MEDIA SOSIAL TERHADAP CHARACTER BUILDING SISWA MADRASAH IBTIDAIYAH
Authors: Zakki Mohammad
Published: June 2024

Tujuan penelitian ini untuk mengetahui dampak media sosial pada pembentukan karakter siswa MI. Darul Hikmah Lebbek Pakong Pamekasan. Metode dalam penelitian ini adalah metode penelitian kualitatif mealui observasi,wawanacar dan dokumentasi. Sedangkan hasil dari penelitian ini adalah media sosial sangat berpengaruh pada siswa dalam pembentukan karakter, lembaga pendidikan selalu bekerjasama dengan pihak keluarga dan masyarakat dalam menjaga dan membatasi penggunaan media sosial pada siswa, dan lingkungan keluarga harus menciptakan pendidikan yang mandiri dengan memberikan teladan yang baik dan mengawasi anak dalam penggunaan media sosial.
Model manajemen sekolah berbasis modal sosial untuk meningkatkan kinerja sekolah di era global
Authors: Wartomo Wartomo
Published: June 2024

This study aims to produce a product in the form of a school management model that is used to improve school performance in SD (Elementary School) Patuk District, Gunungkidul Regency, through a research approach, with the Research and Development (R&D) model of the Dick and Carey development design. The final product of this research is a social capital-based school management model that has been evaluated by education management experts and education management practitioners as well as a limited test. Based on the results of research on the social capital-based school management model to improve school performance in the global era in elementary schools in Patuk District, Gunungkidul Regency, as indicated by the ability of school principals to motivate teachers and students, complete facilities and infrastructure, learning media, supporting books, creating a comfortable, healthy and conducive school organizational climate, so as to create a sense of comfort for students, and he must have dimensions of personality, managerial, entrepreneurial, supervision, and social competencies, while teachers always improve their professionalism, as well as parents or guardians of students cooperate with the school well, then this is supported by the government with the help of educational equipment. So, the social capital-based school management model is statistically proven to be effective in improving school performance in the global era.
Optimalisasi Pembelajaran Pendidikan Agama Islam (PAI) melalui Metode Discovery Learning
Authors: Salmadatu Zaki Afnan , Syamsudin Syamsudin
Published: June 2024

The purpose of this study is to examine the utilization of 21st-century learning approaches in the context of Islamic Religious Education through the implementation of the discovery learning method. Moreover, it aims to present an overview of the educational enhancements achieved by implementing discovery learning, specifically in the field of Islamic Religious Education. The research methodology employed in this study is Library Research, adopting a qualitative approach. The researcher primarily focuses on the utilization of secondary data obtained from various sources such as books, journals, and relevant literature, regardless of their publication status. Data collection involves a thorough examination, analysis, and verification of concrete data pertaining to the research topic through a literature review. The findings of this study demonstrate that the discovery learning method provides students with opportunities to explore, acquire, process, map, and creatively discover new knowledge. In this context, the teacher plays a guiding role in facilitating the learning process. The implementation of the discovery learning method in Islamic Religious Education encompasses six stages: stimulus provision, problem identification, data collection, data processing, real-world validation, and drawing conclusions based on the obtained findings.
Peran guru pendidikan agama Islam sebagai motivator dalam pembentukan karakter terpuji di MIM Program Khusus Putat
Authors: Susilowati Erni , Mujiburrohman Mujiburrohman , Fatimah Meti
Published: June 2024

The aims of this study were (1) to find out the relationship between the role of PAI teachers and the formation of commendable character. (2) Knowing the relationship between teacher motivators and the formation of commendable character. (3) Knowing the relationship between the role of the PAI teacher as a motivator in the formation of commendable character. This study uses a quantitative approach to the research method used is a survey method with correlation techniques using multiple linear regression analysis test. This correlation technique is used to analyze the relationship between the independent variables, namely the role of the PAI teacher (X1) and the motivator (X2) with the dependent variable, namely the formation of commendable character (Y). The population of this study was students at the MIM Putat Special Program, totaling 30 students of class IV Putat Special Program. The sample in this study were all members of the population, namely all students in the Putat Special Program, totaling 30 fourth-grade students in the Putat Special Program. Based on data analysis, it can be concluded that: (1) There is a positive relationship between the role of PAI teachers and the formation of commendable character. This is evidenced by the t count > t table (4.445 > -2.052), (2) There is a positive relationship between teacher motivators in the formation of commendable character. This is evidenced by the t count > t table (-1.494 > -2.052). This is evidenced by the t count > t table (1.488> -2.052) and the values of multiple linear regression are Y'= 4.105+1.434X1+-0.445X2.
Kitab Sunan Ad-Darimi: Perspektif Biografi, Sistematika dan Penilaian Ulama
Authors: Ritonga Muhammad Tohir
Published: June 2024

Penelitian ini bertujuan untuk mendeskripsikan tentang bagaimana biografi kehidupan dan sistematika kitab sunan Ad-Darimi dan mendeskripsikan bagaimana penilaian ulama mengenai kitab Sunan Ad-Darimi. Penelitian ini menggunakan metode penelitian kualitatif deskriptif dengan pendekatan tinjauan kepustakaan, yakni penelitian didukung oleh literature yang terkait dengan permasalahan penelitian. Hasil penelitian menunjukkan bahwa Hasil penelitian menunjukkan bahwa biografi kehidupan dan sistematika kitab sunan Ad Darimi diambil suatu pemikiran bahwa imam ad-Darimi dipercaya sebagai seorang ulama besar, sehingga banyak yang belajar kepada beliau tentang Agama terutama masalah Hadis. Termasuk diantara yang mendengarkan majlis beliau adalah imam al-Bukhari, Muslim, Abu Dawud, at-Tirmizi yang mereka semua lebih tua usianya dari beliau, sedangkan penilaian ulama mengenai kitab Sunan ad-Darimi yaitu kitab ini merupakan salah satu sembilan kitab induk hadis, terlepas dari segala pujian, sanjungan serta penilaian positif yang disampaikan para ulama kepada Imam ad-Darimi, bahwa ditemukan juga beberapa hadis yang berstatus lemah, mursal, mauquf, maqtu‘, bahkan munkar dalam buku tersebut. Hasil penelitian ini diharapkan dapat memberikan kontribusi terhadap ilmu pengetahuan kepada kita untuk lebih mengetahui kepribadian dan karya-karya ulama terdahulu khususnya dalam bidang hadis. Hasil penelitian ini diharapkan dapat memberikan kontribusi terhadap ilmu pengetahuan kepada kita untuk lebih mengetahui kepribadian dan karya-karya ulama terdahulu khususnya dalam bidang hadis.