bluuebunny/crossref_metadata_2025 huggingface dataset:
PM-Gati Shakti: A Case Study of Demand Forecasting
Authors: Reddy M SujayKumar , G Gopakumar
Published: August 2023

PM-Gati-Shakti Initiative, integration of ministries, including railways, ports, waterways, logistic infrastructure, mass transport, airports, and roads. Aimed at enhancing connectivity and bolstering the competitiveness of Indian businesses, the initiative focuses on six pivotal pillars known as "Connectivity for Productivity": comprehensiveness, prioritization, optimization, synchronization, analytical, and dynamic. In this study, we explore the application of these pillars to address the problem of "Maximum Demand Forecasting in Delhi." Electricity forecasting plays a very significant role in the power grid as it is required to maintain a balance between supply and load demand at all times, to provide a quality electricity supply, for Financial planning, generation reserve, and many more. Forecasting helps not only in Production Planning but also in Scheduling like Import / Export which is very often in India and mostly required by the rural areas and North Eastern Regions of India. As Electrical Forecasting includes many factors which cannot be detected by the models out there, We use Classical Forecasting Techniques to extract the seasonal patterns from the daily data of Maximum Demand for the Union Territory Delhi. This research contributes to the power supply industry by helping to reduce the occurrence of disasters such as blackouts, power cuts, and increased tariffs imposed by regulatory commissions. The forecasting techniques can also help in reducing OD and UD of Power for different regions. We use the Data provided by a department from the Ministry of Power and use different forecast models including Seasonal forecasts for daily data.
Laryngeal Complications following Thyroid Surgery: An Update on Bilateral Recurrent Laryngeal Nerve Injury
Authors: Testa Domenico , Vecchio Lucia Del , Motta Giovanni , Conzo Giovanni , Carandente Vincenza , Docimo Giovanni , Apuzzo Giovanni , Conzo Alessandra , Motta Sergio , Docimo Ludovico
Published: August 2023

Bilateral recurrent nerve damage following total thyroidectomy in thyroid surgery represents severe complications. These complications have almost low incidence thanks also by using the Nerve Intraoperative Monitoring. The aim of this observational retrospective study is to evaluate the inception mode and the recovery time for different clinical laryngeal pictures that arise from this surgery. We enrolled 25 patients with bilateral vocal folds mobility deficit between October 2017 and October 2022, diagnosed in ENT Unit of University of Campania “L. Vanvitelli”, out of a total of 1417 patients undergoing total thyroidectomy. The 25 patients (23F,2M) aged from 24 to 78 years old (average age 51.7) presented a bilateral vocal folds motility deficit (occurring in about 0.1% of cases). All patients underwent 9 months diagnostic/therapeutic process, which started approximately 30 days after thyroid surgery. There are several outcomes of these complications with functional laryngeal defects being mainly related to respiratory and phonatory activities. These clinical manifestations evolve in different ways within a context of a wide range of possibilities, from spontaneous bilateral or monolateral recovery to functional or surgical restoration. This study allowed the acquisition of useful information about prognostic indications and an adequate therapeutic process, based on the specific clinical characteristics.
Industrial Scale Direct Liquefaction of Eucalyptus Biomass
Authors: Fernandes Irina , Condenço José , Cecilio Duarte , Correia Maria Joana Neiva , Bordado João Carlos Moura , Mateus Margarida
Published: August 2023

The reagents and raw materials used, as well as the products obtained (bio-oil, reaction condensates, polyols and sugar phases) were characterized by elemental analysis, infrared spectroscopy, thermogravimetry and high performance liquid chromatography with mass spectrometry. The heating value of the bio-oils is higher than that of the original biomass (higher heating value of Eucalyptus sawdust bio-oil 29 MJ/kg versus 19.5 MJ/kg of the original Eucalyptus sawdust). The analyses of the bio-oils allowed to identify the presence of high added-value compounds, such as levulinic acid and furfural. Finally, a study of the accelerated aging of the liquefied biomass showed that the biofuel density increases with the storage time due to the occurrence of repolymerization reactions.
Current Transducer Based on Magneto-Piezoelectret Thermoformed Technology
Authors: Santos Amélia M. , Moreira Rui A.S. , Silveira Tagleorge M. , Altafim Ruy Alberto Pisani , Altafim Ruy Alberto Corrêa
Published: August 2023

This paper introduces a new category of electrical current transducers based on piezoelectrets with thermoformed channels exhibiting magnetic characteristics. These magnetic characteristics gave rise to a new class of piezoelectrets called Thermoformed Magneto-Piezoelectrets (MPTs). Testing the MPTs reaction to external electrical currents showed that these devices respond proportionally to the magnetic fields generated by the applied electrical current. The occurrence of the direct piezoelectric effect is thus verified, and when subjected to magnetic fields produced by electrical currents, the sensor evidenced piezoelectric and piezo-magnetic coefficients of 8300 pC/N and 4980pC/G, respectively. Therefore, the additional layer of magnetostrictive material optimized the piezoelectric characteristics of the MPTs, but also allowed them to respond to external magnetic fields produced by electrical currents.
Alpha-Mangostin: A Potent Inhibitor of TRPV3 and Pro-inflammatory Cytokine Secretion in Keratinocytes
Authors: Dang Thi Huyen , Kim Ji Yeong , Kim Hyun Jong , Kim Byung Joo , Kim Woo Kyung , Nam Joo Hyun
Published: August 2023

The TRPV3 calcium ion channel is vital for maintaining skin health and has been associated with various skin-related disorders. Since TRPV3 is involved in the development of skin inflammation, inhibiting TRPV3 could be a potential treatment strategy. Alpha-mangostin isolated from Garcinia mangostana L. extract exhibits diverse positive effects on skin health; however, the underlying mechanisms remain obscure. This study investigated the TRPV3-inhibitory properties of alpha-mangostin on TRPV3 hyperactive mutants associated with Olmsted syndrome and its impact on TRPV3-induced cytokine secretion and cell death. Our findings demonstrate that alpha-mangostin effectively inhibits TRPV3, with an IC50 of 0.077 ± 0.013 μM, showing inhibitory effects on both wild-type and mutant TRPV3. TRPV3 inhibition with alpha-mangostin decreased calcium influx and cytokine release, protecting cells from TRPV3-induced death. These results indicate that alpha-mangostin reduced inflammation in TRPV3-activated skin keratinocytes, suggesting that alpha-mangostin could be potentially used for improving inflammatory skin conditions such as dermatitis.
Experimental Study on Photodegradation and Leaching of Typical Pesticides in Greenhouse Soil from Shouguang, Shandong Province, Northern China
Authors: Hua Li-Ting , Wu Rui-Lin , Wang Chao-Nan , Li Yi-Long , Xu Fu-Liu
Published: August 2023

Abstract: The migration and transformation of pesticides in the environment will have an impact on the ecosystem. This study collected greenhouse soil from Shouguang, Shandong Province, and studied the photodegradation and leaching of 17 common pesticides in the soil. The results of photodegradation experiments showed that the degradation rate of certain pesticides was increased in the light environment, compared with that in the dark controls. The light half-lives of emamectin benzoate, pyraclostrobin, and metalaxyl were all shorter than their respective dark half-lives, indicating that their residues in soil were greatly affected by light. The leaching experiment showed that the leaching potential of the leachable pesticides was: nitenpyram ≫ metalaxyl > acetamiprid > carbendazim > diethofencarb ≈ chlorantraniliprole > isoprothiolane > oxadixyl > boscalid ≈ tebuconazole > hexaconazole. Pesticides that are easy to leach but not easy to degrade, such as chlorantraniliprole and metalaxyl, have a high potential risk of groundwater pollution, and more degradation technologies should be used to reduce their pollution risk. The study on photodegradation and vertical migration behavior of various pesticides in this study was conducive to providing references for the agricultural use and pollution control of pesticides.
Decarbonisation of Offshore Oil & Gas Production Platforms a Case Study of the North Sea
Authors: Oluka N. , Iyalla I. , Mahon R. , Andrawus J.
Published: August 2023

The United Kingdom Continental Shelf (UKCS) of the North Sea Greenhouse gas emission from offshore oil & gas operations accounts for 14 mega tonnes of Co2 equivalent per annum, the majority of which comes from power generation for platforms (10 mega tonnes per annum of CO2 accounting for 70% of total CO2 emissions). In line with the COP 26 agreements and the Net Zero timeline, Green House Gas (GHG) emissions from power generation for offshore oil and gas platforms is one aspect that is key to the long-term decarbonisation of the North Sea.

In this paper the Sustainability Assessment approach of Multi Criteria Decision Analysis (MCDA) is used to analyse electrification options on a case study offshore oil and gas production platform in the North Sea by considering Technical, Economic and Environmental criteria. These sustainability indicator criteria are then evaluated using Simple Additive Weighting (SAW) to normalise decision making in the ranking process of electrification options.

The results show that decarbonisation of the offshore oil and gas platforms can be achieved by using the sustainability assessment approach to determine the best electrification option available to any offshore production platform.
Modular compliant cube with anisotropic nonlinear responsiveness
Authors: Mi Shengli , Yao Hongyi , Zhao Xiaoyu
Published: August 2023

Compliant mechanisms are a class of mechanical structures in which rigid joints are replaced by flexible components. With its simplified structure and high resilience, the flexible joints bring high precision, low cost and easy maintenance to the compliant mechanisms. However, mainstream compliant mechanisms respond linearly to external excitation via small elastic deformations (< 10%) and cannot expand their sizes and work collectively. Here, we propose an inverse design strategy which generating a family of modular compliant cubes (MCC) with a wide range of elastic deformations (25%~65%) from arbitrary cubic geometry. We found these cubes exhibited mechanical softening undergoing compression stimulus. Further, we built mechanical metamaterials as well as flexible robots by assembling MCCs. These metamaterials were hyperelastic, anisotropic, compressable. The modular flexible robot was metre-scale, free of complex pipelines and traversed complex scenarios on demand. We expect this strategy provide insights into the application of compliant mechanisms in large scale interdisciplinary applications.
Accurate solutions of interval linear quadratic regulator optimal control problems with fractional-order derivative
Authors: Allahdadi Mehdi , Soradi-Zeid Samaneh , Shokouhi Tahereh
Published: August 2023

In this study, the goal is to obtain optimal solutions of fractional interval linear quadratic regulator problems. The major contributions made in this paper is to apply an indirect approach based on the interval calculus of variations with a joint application of constrained interval arithmetic to transcribe the fractional problem under study into a system of Volterra integral equations. To do so, we present the fractional interval Pontryagin's minimum principle for the extraction of necessary optimality conditions. The obtained conditions are first transformed to a system of Volterra integral equations and then using the Laplace transform method, we solve these equations and obtained the optimal solutions. One of the key points of this method is to keeping the continuous form of the problems, which we can change it to an equivalent form without discretizing it, and proving the existence of its solution.
Some numerical examples are carried out to confirm the standard criteria with theoretically accurate results.
Soyabean Oil Concentration Dependent Abundance of Rhamnolipid Homologues Determines Microbial Enhanced Oil Recovery Efficacy In Pseudomonas aeruginosa RA5
Authors: Ankulkar Rutuja , Aphale Durgadevi , Chavan Meera
Published: August 2023

In the present research, we isolated rhamnolipid (RLs) biosurfactant producing Pseudomonas aeruginosa RA5 from oil contaminated refinery soil. The proportion of its major mono-RLs and di-RLs homologues; Rha-C10, Rha-C10-C10, Rha-Rha-C10, and Rha-Rha-C10-C10 was investigated with minor change in the Soyabean oil concentration from 2–4%. We report P. aeruginosa RA5 for its capacity to efficiently produce di-rhamnolipid (Rha-Rha-C10-C10) as the predominant component with 2% and 4% soybean oil as a sole carbon source, accounting for 3.7 % and 0.7% of total products, respectively. The critical micelle concentration (CMC) of rhamnolipid products varies with the content of di-rhamnolipid, whereby lower CMC values correspond to higher di-rhamnolipid contents. The rhamnolipids containing 3.7% di rhamnolipid had the lowest CMC value of 206 mg/L. Accordingly, the viscosity-reducing efficiency and oil-washing efficiency of rhamnolipids increased with the higher di-rhamnolipid component. At a concentration of 1000 mg/L, the rhamnolipids containing 3.7% di-rhamnolipid (Rha-Rha-C10-C10) worked best and showed 85% oil-washing efficiency, which offered great promise for applications in enhanced oil recovery. The results showed the variation of structure and composition of rhamnolipids had a significant effect on their application.
Population-specific reference panel improves imputation quality and enhances locus discovery and fine-mapping
Authors: Terao Chikashi , Flanagan Jack , Tomizuka Kohei , Liu Xiaoxi , Ortega-Reyes David , Matoba Nana , Akiyama Masato , Ishigaki Kazuyoshi , Ashikawa Kyota , Takata Sadaaki , Aoi Tomomi , Momozawa Yukihide , Ito Kaoru , Murakami Yoshinori , Matsuda Koichi , Kamatami Yoichiro , Morris Andrew , Horikoshi Momoko
Published: August 2023

In order to improve the imputation quality for genome-wide association studies (GWAS) conducted on the Japanese population, we created and assessed four Japanese population-specific reference panels. These reference panels were generated using whole genome sequencing (WGS) data, encompassing diverse sample sizes (3K ~7K Japanese enrolled through the Biobank Japan (BBJ) project), and varying sequencing depths (3× to 30×). An augmented reference panel that included 7,472 Japanese WGS of mixed depth (1000 genome project (1KG)+7K) provided the greatest improvement in imputation quality relative to the 1KG panel alone, with ~2× the total number of imputed variants and ~3.8x the number of “well-imputed” variants (defined by r2 > 0.3). Furthermore, most these improvements were observed for rare variants with a minor allele frequency (MAF) < 1%. To demonstrate the benefits of improved imputation in association analyses of complex traits, a GWAS of serum uric acid levels was performed after imputation up to the 1KG+7K panel. The analysis revealed four potentially novel loci at genome-wide significance (P<5×10-8) distinct from those previously reported. In summary, the augmented imputation panel demonstrates significant advantages in the discovery and fine-mapping of complex trait loci, particularly those influenced by low-frequency association signals.
Expert deduction rules in data mining with association rules: new results and challenges
Authors: Rauch Jan
Published: August 2023

The paper deals with applications of domain knowledge in data mining with association rules. We consider enhanced association rules – general relations of general Boolean attributes derived from columns of analyzed data matrices. The challenge is to filter out rules – consequences of given items of domain knowledge. The general syntax of enhanced rules motivated the study of logical calculi whose formulas conform to these rules. Deduction rules in such calculi have proven inadequate for dealing with domain knowledge. This led to the definition and study of expert deduction rules – incorrect deduction rules, which are, however, supported by indisputable facts on the whole calculus. Such expert deduction rules can remarkably reduce the number of output association rules by omitting the consequences of given items of domain knowledge. This concerns both the association rules produced by the apriori algorithm and the enhanced association rules. However, expert deduction rules are available only for association rules evaluated using the confidence measure of interest. New expert deduction rules for association rules evaluated using the lift measure of interest are defined and studied. Two case studies demonstrate their usefulness. Finally, new challenges to study expert deduction rules are formulated.
Holography for bulk states in 3D quantum gravity
Authors: Raeymaekers Joris , Vos Gideon
Published: August 2023

In this work we discuss the holographic description of states in the Hilbert space of (2+1)-dimensional quantum gravity, living on a time slice in the bulk. We focus on pure gravity coupled to pointlike sources for heavy spinning particles. We develop a formulation where the equations for the backreacted metric reduce to two decoupled Liouville equations with delta-function sources under pseudosphere boundary conditions. We show that both the semiclassical wavefunction and the gravity solution are determined by a universal object, namely a classical Virasoro vacuum block on the sphere. In doing so we derive a version of Polyakov’s conjecture, as well as an existence criterion, for classical Liouville theory on the pseudosphere. We also discuss how some of these results are modified when considering closed universes with compact spatial slices.
Trajectory planning and control algorithm of industrial robot manipulator
Authors: Liu Jing
Published: August 2023

As the industrial robot task becomes more complex, the difficulty of trajectory planning and tracking control of manipulator is gradually increasing. To minimize the vibration during the manipulator motion and improve the planning accuracy, the method of quintic polynomial combined with non-uniform B-spline interpolation is studied for joint space (JS) planning. The trajectory tracking system is easily affected by friction nonlinearity and parameters. So a JS trajectory tracking controller based on based on fuzzy neural network (FNN) is designed. Through simulation experiments, the curve obtained by the planning method studied is smoother and the planning error is minimum. The maximum position error is 0.09 rad, and the speed error is not more than 0.1 rad/s. The controller performance test results under different parameters show that the W^, c^, κ^ parameter in FNN can be adjusted in real time, and the value will not affect the performance of the controller. The fluctuation range of trajectory error of different joints is within ±0.2×10-5rad, which indicates that the performance of AFNNC controller studied is better. And its response time is the shortest and its robustness is better when the load changes suddenly.
How will the conflict in Ukraine affect the system of international information security?
Authors:   Irkutsk State University, Sebekin Sergey
Published: August 2023

The article is devoted to the consideration of the main changes taking place in the system of ensuring international information security after the start of a special military operation in Ukraine. An attempt is made to predict the challenges and risks that the IIS system will face in the future. The priority transformations are connected with the negotiation process within the UN, which, in the context of increasing political antagonism between the key subjects of the dialogue, is becoming increasingly politicized and is beginning to experience some difficulties. It is assumed that in the conditions of the new political reality, the issue of “comprehensive” counteraction to international cybercrime will remain unresolved. There is some fragmentation of the international information security system itself, which is experiencing centrifugal tendencies in terms of promoting alternative approaches to solving key issues in this sphere. Finally, it can be expected that the United States, in interaction with Russia, will more actively engage in a proactive strategy of so-called defend forward, which should be implemented through the concept of persistent engagement. The preliminary conclusions demonstrated by the actions in Ukraine regarding the role and place of cyber attacks directly within the framework of the armed conflict are also considered. It is assumed that in the near future cyber attacks will not be considered as a means of achieving real strategic effects on the battlefield, where conventional weapons play a dominant role. An attempt is made to give some recommendations on maintaining a certain dynamic of the development of the IIS system.
Social effects of neoliberal policy in post-Soviet Saint Petersburg: Urban space contestation revisited
Authors:   Sociological Institute of the Russian Academy of Sciences — Branch of the Federal Center of Theoretical and Applied Sociology of the Russian Academy of Sciences, Tykanova Elena V. , Khokhlova Anisya M. ,   St. Petersburg State University
Published: August 2023

Neoliberal city policy has become central for urban planning and (re)development in postsoviet St. Petersburg. Competing views on how urban space should be organized make citizens consolidate and buck the decisions of strong advocacy groups. This paper considers the contestation of urban space by urban dwellers and city elites in the early times of establishment and spread of neoliberal rhetoric and policy. It focuses on four cases of local communities struggling against spot construction, demolition, and renovation of historical areas (2005–2012). Empirically, the paper relies on a series of semi-structured interviews with local residents and activists as well as materials of semi-formalized observations at local gatherings and rallies. We use theories of urban political regimes to analyze the decisions on urban futures made by administrations and developers, and the theories of Lefebvre, Scott, and de Certeau providing insights into everyday grassroots resistance of citizens to structural pressures, domination and exploitation — to describe the responses of urbanites. Our data shows that these theories need to be adapted to the local context, where struggles over urban space unfolded under the conditions of total uncertainty including multiple property regimes, unstable legal frameworks, non-transparent decision-making by city authorities and investors, and rising tradition of civic participation. As a result, we question the scholarly convention about the paternalistic relations between urbanites and powerholders, and problematize the boundaries between the core concepts of urban theory: in particular, we demonstrate the relative nonbinary character of the opposition of spatial strategies vs. spatial tactics.
Green practices of citizens: Sources, stabilization and dissemination (case of Tyumen)
Authors:   University of Tyumen, Zakharova Olga V. , Karagulian Egine A. ,   University of Tyumen, Payusova Tatiana I. ,   University of Tyumen
Published: August 2023

Changing planetary conditions force all actors of social processes to transform social practices. A significant role of society greening belongs to socio-political activism, which becomes a mechanism for launching innovations and changes practices. This article studies the sources of green practices of citizens, the mechanisms of stabilization and dissemination of new practices by questioning the population in Tyumen. To achieve this goal, we formulated five hypotheses. The study did not confirm the hypothesis that green practices arise due to school education, that the authorities are the initiators of greening society, that young people are the driving force of green practices. The obtained data partially confirmed the hypotheses that the green practices of the population are not regular and involvement in green practices occurs through ecological communities. It was found that from 30 to 71% of Tyumen residents know about green practices and are engaged in them. The most common are both practices that have a long history — cleaning the territory, planting trees, and modern practices — taking care of pets, separate waste collection. Respondents consider environmental organizations, activists, and environmental foundations to be initiators and key drivers of green practices. The research contributes to understanding how green practices appear, how they gain their supporters, how they spread in society. Our research can be useful for authorities for improving of the greening process.
Hdt. 4.79 διεπρήστευσε
Authors:   Ludwig-Maximilians-Universität München, Nikolaev Alexander
Published: August 2023

This paper examines the form διεπρήστευσε, obelized in the editions of Herodotus. There have been two ways of interpreting the form: some scholars have taken it to refer to an act of speech, while others have sought here a verb of motion. Both groups of scholars proposed a variety of conjectures, some of them addenda lexicis and none of them commanding immediate acceptance. After a review of various solutions that have been proposed to-date, this paper argues in favor of retaining the reading of the paradosis and analyzing (-)πρηστεύω as a verb of quick motion. The verb is argued to be an Ionic colloquialism (or even Herodotus’ own Augenblicksbildung), derived from the root of πίμπρημι in its original meaning ‘to blow’ (of which ‘to burn’ is a secondary development) via an agent noun πρηστήρ / *πρήστης, cf. μνηστεύω ‘woo’ : μνηστήρ ‘suitor’ or δυναστεύω ‘hold power’ : δυνάστης ‘person with power’. The proposed translation ‘blasted, dashed’ is supported by typological parallels for the semantic development ‘to blow’ → ‘to move (impetuously)’, such as Old English bl.́stan ‘to blow; to move impetuously’ or Russian dut’ ‘to blow; to dash, to rush’. Interestingly, Hittite (parip) parāi-, the cognate of Gk. πίμπρημι, may show the same semantic
Nec vero contemnendum vulgus interdum est: Vernacular animal names among Theodore Gaza’s Latin neologisms
Authors:   Ghent University, Vorobyev Grigory
Published: August 2023

The article discusses the origins of four Neo-Latin animal names, denoting a beetle, a bird, a fish and a mollusk, coined by the Greek scholar Theodore Gaza in the third quarter of the fifteenth century: two neologisms of form, or proper neologisms, gal(l)eruca and gallinago, and two neologisms of sense, cernua ‘inclined forwards, head foremost’ and patella ‘plate, pan’. These words, still valid in today’s zoological nomenclature, were first introduced in Gaza’s Latin version of Aristotle’s Historia animalium, where they stood, respectively, for μηλολόνθη, σκολόπαξ/ἀσκαλώπας, ὀρφώς/ὀρφός and λεπάς. Apparently, they owe their existence to Gaza’s acquaintance with Italian dialectal vocabulary, as can be deduced from two sixteenthcentury sources: Agostino Nifo’s commentary to Aristotle’s zoological writings and Ippolito Salviani’s encyclopedic work on aquatic animals. Gaza’s galleruca must have originated from the Lombard galeruca ‘rose chafer’ (the identification of μηλολόνθη with the latter probably due to the hapax legomenon χρυσομηλολόνθιον, Ar. Vesp. 1341), gallinago from the Emilian gallinazza ‘woodcock’ (since the only known characteristic of σκολόπαξ/ἀσκαλώπας is that it is similar to a hen, Arist. Hist. an. 617b24), cernua from the Calabrian cerna/cernia (identified with ὀρφώς/ὀρφός either due to Gaza’s use of a bilingual glossary or due to his own experience in the Calabrian bilingual milieu) and patella from the Calabrian or Roman patella ‘pan; limpet’ (perhaps identified with λεπάς because Gaza kept in mind the name of a vessel, λεπαστή/λεπάστη, considered deriving from λεπάς by Eustathius). All the said dialects correspond to the Italian regions where Gaza spent parts of his life.
The sustainability of groundwater in semi-arid regions: the case of Makutupora Basin in Tanzania
Authors: Mseli Zaina Hussein , Said Alfred , Sankaranna Gaduputi , Mwegoha William John
Published: August 2023

Groundwater sustainability ensures groundwater development and uses to meet current and future needs without causing unacceptable environmental, economic, or social consequences. In semi-arid regions, water resources are typically limited, and water management is critical to ensure a sustainable water supply. Groundwater sustainability indexing is vital for groundwater management. The study used four indicators in six dimensions, i.e., quantitative and qualitative hydrogeology, environmental, social-economic, and political factors, to evaluate the sustainability of the aquifer in Makutupora basin, Dodoma, Tanzania. The resulting aquifer sustainability index is 0.59, with a 95% confidence interval between 0.3856 and 0.7944, showing that the aquifer is sufficiently sustainable. The hydrogeological analysis revealed that groundwater sustainability is promising, although groundwater use per capita is alarming. This study also recommends effective water management strategies, including improving water use efficiency, promoting water conservation, implementing policies to limit water withdrawals, and promoting alternative water sources such as recycled wastewater, especially for agricultural activities.
Drug Repurposing against Novel Therapeutic Targets in Plasmodium falciparum for Malaria: The Computational Perspective
Authors: Rai Shweta , Shukla Shruti , Scotti Luciana , Mani Ashutosh
Published: August 2023

:

Malaria remains one of the most challenging tropical diseases. Since malaria
cases are reportedly alarming in terms of infections and mortality, urgent attention is
needed for addressing the issues of drug resistance in falciparum malaria. High throughput
screening methods have paved way for rapid identification of anti-malarial. Furthermore,
drug repurposing helps in shortening the time required for drug safety approvals.
Hence, discovery of new antimalarials by drug repurposing is a promising approach for
combating the disease. This article summarizes the recent computational approaches
used for identifying novel antimalarials by using drug target interaction tools followed by
pharmacokinetic studies.
Dietary, Herbal and Nutritional Interventions for Managing Rheumatoid
Arthritis: A Review
Authors: Verma Aanchal , Dubey Nandini , Agrawal Anant , Goyal Ahsas
Published: August 2023

Rheumatoid Arthritis (RA) is a systemic, inflammatory disease that affects joints and
leads to progressive cartilage and bone deterioration. The susceptibility to RA is determined by
genetic and environmental factors. Recently, many efforts have been undertaken to develop natural
compounds capable of reducing the symptoms of RA to avoid the negative effects of the current
anti-inflammatory drugs. Interestingly, substantial data has revealed that nutritional, and herbal
supplements may be effective adjuvants in reducing the symptoms of RA by influencing the
pathogenic inflammatory processes. In this context, various kinds of food, phenolic substances,
spices like ginger, and turmeric, several vitamins, and probiotics are reported to control the activity
of inflammatory molecules implicated in the pathophysiology of RA and therefore, have proved
successful in slowing the course of this arthritic illness. Therefore, the goal of this review article is
to compile various findings on RA that have revealed illuminating information about the antiinflammatory,
antioxidant, analgesic, immunomodulatory, and bone erosion-preventing properties
of nutritional, and herbal components. Conclusively, this review concentrates on natural ingredients
that may enhance overall well-being, promote health, and lessen the risk of RA.
Neuropathic Pain in Aged People: An Unresolved Issue Open to Novel
Drug Approaches, Focusing on Painful Diabetic Neuropathy
Authors: Marchesi Nicoletta , Fahmideh Foroogh , Pascale Alessia , Allegri Massimo , Govoni Stefano
Published: August 2023

A majority of older patients suffer from neuropathic pain (NP) that significantly alters their
daily activities and imposes a significant burden on health care. Multiple comorbidities and the risk of
polypharmacy in the elderly make it challenging to determine the appropriate drug, dosage, and
maintenance of therapy. Age-dependent processes play a contributing role in neuropathy given that diabetic
neuropathy (DN) is the most common form of neuropathy. This narrative review is mainly focused
on the drug treatment approach for neuropathy-associated pain in aged people including both
drugs and dietary supplements, considering the latter as add-on mechanism-based treatments to increase
the effectiveness of usual treatments by implementing their activity or activating other analgesic
pathways. On one hand, the limited clinical studies assessing the effectiveness and the adverse effects
of existing pain management options in this age segment of the population (> 65), on the other hand,
the expanding global demographics of the elderly contribute to building up an unresolved pain management
problem that needs the attention of healthcare providers, researchers, and health authorities as
well as the expansion of the current therapeutic options.
Inflammation in Posttraumatic Stress Disorder: Dysregulation or
Recalibration?
Authors: Patas Kostas , Baker Dewleen G. , Chrousos George P. , Agorastos Agorastos
Published: August 2023

Despite ample experimental data indicating a role of inflammatory mediators in the behavioral
and neurobiological manifestations elicited by exposure to physical and psychologic stressors,
causative associations between systemic low-grade inflammation and central nervous system
inflammatory processes in posttraumatic stress disorder (PTSD) patients remain largely conceptual.
As in other stress-related disorders, pro-inflammatory activity may play an equivocal role in PTSD
pathophysiology, one that renders indiscriminate employment of anti-inflammatory agents of
questionable relevance. In fact, as several pieces of preclinical and clinical research convergingly suggest,
timely and targeted potentiation rather than inhibition of inflammatory responses may actually be
beneficial in patients who are characterized by suppressed microglia function in the face of systemic
low-grade inflammation. The deleterious impact of chronic stress-associated inflammation on the
systemic level may, thus, need to be held in context with the - often not readily apparent - adaptive
payoffs of low-grade inflammation at the tissue level.
Pediatric Malnutrition and Natural Dietary Supplementary Food to
Overcome it: A Review
Authors: Kesharwani Rohit Kumar , Fatima Sana , Bajpai Meenakshi
Published: August 2023

Malnutrition is described by the World Health Organization (WHO) as a person's energy
and/or nutrient consumption being insufficient, excessive, or out of proportion. Health officials in
India are quite concerned about malnutrition in children under five. Recent research revealed a significant
frequency of undernutrition among children under the age of five. It is estimated that malnutrition
affects roughly 2/3 of India's population under the age of five and that 5-8% of those children
are severely malnourished. It could be argued that it is one of the most prevalent issues affecting
children's health in the nation. Mothers' nutritional health, breastfeeding habits, women's education,
and cleanliness are all factors that contribute to malnutrition. The use of dietary supplements is
widespread, and they are a class of ingestible goods that can be distinguished from common meals
and medications. Over the past few decades, the demand for phytonutrients has increased, and individuals
are now using them to meet their nutritional needs. This review enlightens and explores the
prevalence of undernutrition, its causes, and the necessary countermeasures, treatments for malnutrition
among children under the age of five in India and nutritional diversification of food and other
benefits which make it a better choice to use in our daily diet to combat pediatric malnutrition.
O contexto de uso do termo Arquivos Comunitários a partir da vertente dos estudos críticos e decoloniais uma análise terminológica pontual
Authors: Alencar Maíra Fernandes , Nogueira Brígida Maria , Barité Cervantes, Mário
Published: August 2023

The objective of this work was to analyze the context of use of the term Community Archives, based on the scientific production in the period 2008-2021 of three members of the Archival Education Research Initiative(AERI)discursive community. The methodology is exploratory and descriptive, and made use of Hjorland's Domain Analysis in the terminologicaldimension, but with apunctual focus. As for results, it was possible to reach ten categories in total. The predominance was the category of the political dimension with 81.25% of the works, in a corpus of 16 articles. This shows a dimension of engagement, so that it is possible to understand that, considering the context of use of the term community archives in the discursive community of AERI, this theme has meanings of actions aimed at marginalized social groups, since the emphasis given lies in the perspective of making thehistory of such groups accessible, based on their own ways of acting in political activism
Promoção dos ODS nas bibliotecas de Universidades Federais Brasileiras influência das práticas informacionais e das comunidades de prática na atuação dos bibliotecários
Authors: Trindade Alessandra Stefane Cândido Elias da , Rangel Tayná Ladislau , Moreno Danielle Harlene da Silva , Cerveró Maria Aurora Cuevas , Valero Pablo Parra , Nascimento Geysianne Felipe do
Published: August 2023

The Sustainable Development Goals (SDG) are 17 global goals aimed at fostering the economic, social and political development of regions, countries, and therefore the planet. Although libraries are cultural equipment indispensable for the development of the SDG, their performance depends on the social and informational practices of the librarians. Objective: To investigate the promotion of SDG in Federal Universities(FU)libraries in Brazil. Methodology: This study of an applied nature, is explanatory, uses a mixed approach (quantitative-qualitative) and questionnaire as a technique of data collection.Results: It is noteworthy that the questionnaire was answered by 58 professionals. All Brazilian FUlibraries can develop actions capable of contributing to the advancement of the SDG, however, some do so unintentionally. Conclusions: There are librarians who do not know the SDG and libraries that intentionally and unintentionally develop actions and activities related to the SDG. The informational practices of librarians can influence their professional performance, including with regard to the development of the SDG. Communities of practice are excellent means of accessing information, participating in these communities can help librarians in the process of innovation of university library products and services.
Memória social dos quilombos do Cariri um acervo virtual em construção
Authors: Santana Wagner , Régis Priscilla
Published: August 2023

The lack of registration of the oral traditions of quilombola communities and the urgent need to strengthen the quilombos in a context of persecution and invisibility justify this research, which seeks to contribute to the production of knowledge as well asto collect memory and oral tradition of the Quilombo Serra dos Mulatos, in Jardim/CE. In a qualitative approach, we used bibliographical research and documental survey. In a later stage, field research will becarried out with the application of interviews and complementary methodologies. The objective is to capture and understand the memories that permeate the process of self-recognition and the potential impact of preserving the quilombola memory in the reality of the community. This is an important contribution to valuing the country's cultural diversity and to strengthening the remaining quilombo communities, ensuring that future generations have access to those oral traditions and the memory of their ancestors.
REGULAÇÃO PELA TECNOLOGIA COMO RESPOSTA ESTATAL À DESCENTRALIZAÇÃO NO SETOR FINANCEIRO CONTEMPORÂNEO
Authors: Lourenço da Costa Pedro Henrique
Published: August 2023

Este estudo tem como objetivo analisar a interação entre a descentralização financeira, a regulação e a soberania estatal no contexto das tecnologias emergentes. Concentrando-se nas finanças descentralizadas (DeFi) e nas implicações da tecnologia blockchain, o estudo aborda três tópicos principais: as finanças descentralizadas (DeFi) e seu impacto na estrutura do sistema financeiro tradicional, a resposta dos reguladores financeiros ao fenômeno DeFi e o papel regulatório das moedas digitais soberanas. O texto também discute os desafios associados à disrupção do sistema financeiro pela introdução de elementos descentralizados, que diminuem sensivelmente a capacidade de implementação de política monetária pelo regulador estatal. Os reguladores financeiros estão respondendo a essas mudanças disruptivas, buscando alternativas que preservem sua participação ativa na implementação da política monetária. A introdução de Moedas Digitais de Bancos Centrais (CBDCs, no acrônimo em inglês) é considerada uma possível alternativa para manter o controle estatal sobre a política monetária em um ambiente cada vez mais descentralizado. No entanto, essa questão vai além do controle econômico, envolvendo disputas políticas e institucionais. A preservação da autoridade do Estado é um ponto-chave na análise das instituições dominantes na regulação do sistema financeiro tradicional e suas reações às inovações descentralizadas. Portanto, este estudo tem como objetivo contribuir para uma compreensão mais aprofundada da interação complexa entre tecnologia emergente, descentralização financeira, regulação e soberania estatal.
Potential Application of Structural Linguistics Methodology in the Network Analysis of Roman and Medieval Regulae Iuris
Authors: Kotlyar Ilya Andreevich
Published: August 2023

The article presents the preliminaryresults of the research of Roman and medieval Regulae iuris using a novel combination of methods. It demonstratesthe productivity of combining network analysis and the methodology ofstructural linguistics in the analysis of the database of Latin ‘rulesof law’,which were juristic generalizations of the legal matter. This methodology allowsmeasuring the extent to which scholastic dialectics helped medieval learned juriststo achieve a systematization of law, as well as offers a good combination of historicaland dogmatic approaches, so important in the research of normative systems,especially in law and legal history.  
Influence of the upper electrode material on the electrophysical properties of MDM structures based on ferroelectric films
Authors: Afanasyev M. S.  , Belorusov D. A.  , Kiselev D. A.  , Chucheva G. V.
Published: August 2023

Ferroelectric films of the composition Ba0.8Sr0.2TiO3 (BST) were synthesized on platinized silicon substrates by RF sputtering. Top electrodes made of nickel, aluminum, copper and chromium were formed on the grown films by electron beam sputtering. The results of studies of the electrophysical properties of the obtained metal-dielectric-metal (MDM) heterostructures (Me-BST-Pt-Si) are presented. Keywords: ferroelectric BST films, metal-dielectric-metal (MDM) structures, microstructure, electrophysical properties.
Pyroelectric effect in doped nonpolar glycine crystals
Authors: G.U. Sotnikova  , P.S. Zelenovskiy  , A.D. Ushakov  , G. A. Gavrilov  , V. Shur  , A.L. Kholkin
Published: August 2023

Doping-induced local symmetry breaking of centrosymmetric molecular crystals endows them with piezoelectric and pyroelectric properties. In this work, we measured temperature dependences of pyroelectric and piezoelectric coefficients in α--glycine crystals single-doped by threonine and double-doped by threonine and alanine. We analyzed primary and secondary pyroelectric effects in these crystals and suggested a model of the dopant complexes related to the observed effects. Keywords: pyroelectricity, α-glycine, doped molecular crystals.
The Psychometric Properties of the COVID Stress Scales in Korean University Students
Authors: Lee Boram , Jeong Hyelin
Published: August 2023

The COVID-19 pandemic and its associated disruptions have significantly impacted university students’ lives worldwide. The COVID Stress Scale (CSS) is a 36-item self-reporting instrument designed to measure stress caused by the COVID-19 pandemic. This study purposed to examine the psychometric properties of the Korean version of the CSS for use with Korean university students. The study sample comprised 402 undergraduate students enrolled in a four-year private university in central South Korea. This cross-sectional investigation employed an anonymous online survey conducted during the peak of the COVID-19 pandemic. The forward-backward translation method was adopted to convert the original English version of the CSS to Korean. Confirmatory factor analysis (CFA) was performed to determine the structure of the CSS. Convergent validity was assessed using correlation analysis with the Hospital Anxiety and Depression Scale (HADS). McDonald’s omega and Cronbach’s alpha reliability coefficients were used to evaluate reliability. The results revealed that a bifactor model specifying general factors and the six specific factors of danger, contamination, socioeconomic characteristics, xenophobia, traumatic stress symptoms, and compulsive checking and reassurance seeking provided the best fit among all alternatives. Further investigations demonstrated that the general factor of COVID-19-related stress accounted for the majority of CSS variances than the six specific factors. The results highlighted the unidimensionality of the measure. Additionally, the actions displayed excellent internal consistency. Our findings endorse the use of the Korean version of the CSS as a tool for measureing general stress experienced in reaction to the COVID-19 pandemic and we support using the instrument’s total score in this context. 