bluuebunny/crossref_metadata_2025 huggingface dataset:
Behind the Saying “Landsbergis Destroyed the Collective Farms”: Transformation of Agriculture from the Perspective of Cultural Trauma Narrative
Authors: Budreckaitė Valda
Published: March 2023

This article explores what is told about the supposed “collapse” of the collective farms in Lithuania, how is the negative connotation explained, and how is it attuned to the negative understanding of collectivization and collective farms in general. Relying on the theoretical literature dedicated to narrative and trauma, a scheme of cultural trauma narrative is formulated as a conceptual tool. Through narrative analysis of qualitative interviews collected in Panevėžys, Jonava, and their vicinities in 2021, it is demonstrated that the collective farm of early Soviet times is seen negatively, but the collective farm of late Soviet times is defined as a consistent unit. During transformation, this unit is suddenly disintegrated. Ordinary people are defined as the main victims. The named perpetrators can be divided into two groups. The first one is local people: the former chairs of the collective farms and other local leaders are mostly mentioned, as well as the “smarter ones” (“gudresnieji”). The second group is comprised of National government and Vytautas Landsbergis (personally); they are assigned a fatal role. A group of “critics” has been analytically distinguished. These informants have been harshly critical of collective farms regardless of times and distanced themselves from parlance regarding the “collapse” of collective farms. However, some of the “critics” repeated some elements of the cultural trauma narrative.
FEED EFFICIENCY AND GROWTH OF CATFISH (Clarias sp.) FED WITH THE ADDITION OF IMMUNE-BOOSTING FERMENTED EARTHWORMS
Authors: Djalil Mukhlisnah , Isnansetyo Alim , Triyanto Triyanto , Nugraha Tito Arya
Published: March 2023

A fermented earthworm (FEW) is reported to be an alternative to an immune-modulator feed additive in catfish. However, the effects on growth and feed efficiency have not been reported yet. The present study aimed to evaluate the effects of fermented earthworms (FEW) on the growth and feed efficiency of catfish (Clarias sp.). A feeding trial was conducted in a completely randomized design with five treatments of diet in quadruplicate. The trial was conducted for 78 days. The observed parameters comprised of survival rate (SR), specific growth rate (SGR), feed conversion ratio (FCR), feed efficiency (FE), protein efficiency ratio (PER), and total biomass. The results revealed that the FEW at up to 5% did not affect (P>0.05) the growth rate of catfish, but FEW gave a negative effect on the growth rate (P>0.05) at the addition rate higher than 5%. The highest growth rate was found at the addition rate of 2.5%. FEW also did not affect the survival rate (SR), FCR, PER, and total biomass (P>0.05). This study successfully confirmed that FEW could be used as an alternative to immuno-modulator ingredient without any negative impact on the growth of catfish when FEW was added to the feed at as high as 5%. These findings give a new perpective in utilizing FEW as a fuctional aqua-feed ingredient to increase immune response without alteration of the fish growth.
\(\textit{Schisandra grandiflora}\) (Wall.) Hook. F. & Thomson (Schisandraceae: sect. \(\textit{Pleiostema}\)), a new record for the flora of Vietnam
Authors: The Cuong Nguyen , Van Hai Do , Thi Hoan Duong
Published: March 2023

Schisandra grandiflora (Wall.) Hook. f. & Thomson (Schisandraceae: sect. Pleiostema), the specimens collected in Ha Giang, Cao Bang, and Vinh Phuc provinces, as a new recorded species for the flora of Vietnam. A morphological comparison with related species and a key to species in Vietnam was provided. A description including details of distribution and habitat is supplied with a line-drawing.
Genetic variations of filaggrin encoding gene \(\textit{(FLG)}\) in the Vietnamese population revealed from whole-exome sequencing
Authors: Nhung Vu Phuong , Giang Nguyen Huong , Hong Nhung Nguyen Thi , Ton Nguyen Dang , Ha Nguyen Hai
Published: March 2023

Filaggrin is a key protein that facilitates terminal differentiation of the epidermis and maintains skin barrier function. Mutations in the gene encoding filaggrin (FLG) have been identified to cause ichthyosis vulgaris, increase the risk of atopic dermatitis and other skin diseases. In this study, we established the database of FLG gene obtained by whole-exome sequencing (WES) of 244 Vietnamese. We also estimated allele and genotype frequencies of the FLG gene in this Vietnamese population and predicted the impact of novel variants on protein function using in silico analysis tools. The detected variants included 126 nonsynonymous, six nonsense mutations, six frameshift insertions/deletions, and one non-frameshift deletion, mostly located in exon 3. Of which, there were 11 novel variants have been identified and four of them were predicted as detrimental for encoding protein. Remarkable pathogenic variants were mostly nonsense variants, showing the main genetic factor underlying the pathology of diseases caused by FLG. The results obtained in this study would provide essential information about the genetic characteristics of FLG in the Vietnamese population and the risk of occurrence of diseases related to this gene, which facilitates the development of new specific and accurate diagnosis, treatment, and prevention options for FLG-related diseases, particularly in Vietnamese.
Characteristic of multiple-antibiotic-resistant \(\textit{ Salmonella enteritica }\) from Muscovy duck in Hanoi
Authors: Nguyen Trung , Le Hoa , Ta Yen , Pham Da , Nguyen Nam , Nguyen Hoang
Published: March 2023

Nowadays, as the global population grows, the demand for food is also becoming higher each day. Together with the rise in food demand, Muscovy duck has been gradually bred industrially as a poultry food supply along with the chicken. The change from traditional to industrial breeding poses a potential risk of pathogenic bacteria infection and antimicrobial resistance bacteria. Especially Salmonella, one of the leading pathogens worldwide, is also notable for its antimicrobial resistance. In this study, by using Muscovy duck carcasses collected from wet markets in 05 districts in Ha Noi, we assessed the rate of Salmonella infection at first, then conducted an antibiotic susceptibility test utilizing 15 types of antibiotics, from then whole genome sequencing was applied for 8 multidrug resistant isolates. Next, the genomic data after successfully sequenced was used for analyzing antibiotic resistance genes, genotypes, multi-locus sequence-based typing (MLST), virulence factors, and plasmids. 65% of Muscovy duck samples were positive for Salmonella, in which 95% (19/20 strains) of Salmonella isolated was multidrug resistant. The result of the antibiotics susceptibility test indicated that phenotypic resistance to ampicillin was the most observed (92.3%, 19/20), followed by tetracycline (90%, 18/20), cefuroxime (85%, 17/20), cefazolin (85%, 17/20), ceftriaxone (85%, 17/20), Cefotaxime (85%, 17/20), trimethoprim (70%, 14/20), gentamicin (60%, 12/20), chloramphenicol (55%, 11/20), nalidixic acid (55%, 11/20), ceftazidime (50%, 10/20), ciprofloxacin (2/20). However, all isolates were susceptible to cefoxitin and meropenem. Sixty-five antibiotic resistance genes were identified, including genes that are resistant to aminoglycoside, 3rd generation antibiotics (cefotaxime, cefoperazone, ceftizoxime, ceftazidime, ceftriaxone, etc.). Col, IncA plasmids and some mobile genetic elements were identified. Simultaneously Salmonella pathogenic islands were found in all sequenced strains, exclusively SPI 1, SPI 3, and SPI 9 were carried in every isolate.
Use of dietary garlic \(\textit{(Allium sativum L.) }\) and Vietnamese balm\(\textit{ (Elsholtzia ciliata)}\) extract for prevention of Bacillary Necrosis in Pangasius (BNP) in striped catfish (Pangasianodon hypophthalmus)
Authors: Phuc Khang Luu Tang , Vinh Truong , Le Tho Luong Thi , Tong Nguyen Xuan , Phuong Dung Tran Thi
Published: March 2023

Garlic (Allium sativum) and Vietnamese balm (Elsholtzia ciliata) are well-known herbs that have been widely used in Vietnamese traditional medicines. However, studies on the effects of these plants in improving the immune system of fish have received less attention. This study aimed to investigate the effect of ethanolic leave extracts from garlic and Vietnamese balm leaves on the growth and immune response of striped catfish (Pangasianodon hypophthalmus) for the prevention of Bacillary Necrosis of Pangasius. Bacillary Necrosis of Pangasius (BNP) caused by Edwardsiella ictaluri is the most serious disease occurring in farmed striped catfish in Vietnam. The experiment was in a completely randomized design with five triplicated treatments including 0% (control); 2% and 4% of garlic and 2% and 4% of Vietnamese balm leaves extract. Fish were soaked with E. ictaluri. Samples were collected on the days 7th and 14th of the growth experiment and days 3rd, 5th and 7th of the challenge test. Fish mortalities and immune response among challenge tests were also recorded. The results suggest that plant extracts possibly modulate the striped catfish’s immune response in a time and dose dependent manner. Specifically, diets enriched with extracts of A. sativum at 4% have great potential than Vietnamese balm extraction for improving striped catfish health by enhancing the immune system. After challenging with E. ictaluri, the accumulative mortality of fish in garlic and Vietnamese balm leaves treatments was lower than that of the control. The mortality of fish fed with 4% garlic extract was the lowest. These results indicated that supplementation of 4% garlic extract significantly improved the resistance to the BNP infection in striped catfish and has the ability to add fish feed in reality.
Typification and novelties in Rubiaceae for the flora of Vietnam
Authors: Hong Quang Bui , Duc Binh Tran , Ngoc Diep Tran Thi , Thuy Duong Tran Thi , Tuan Anh Le
Published: March 2023

Four Rubiaceous species viz. Hedyotis diversifolia, Involucrella lithophila, Mouretia larsenii, Ophiorrhiza cana are newly recorded for the flora of Vietnam. Morphology based identification key, taxonomic notes, and photo-plates of the newly reported species are provided. Moreover, the second-step lectotype has been designated for the name Involucrella chereevensis. These findings provide some new basic data essential for biodiversity research in Vietnam. key, taxonomic notes, illustration provided.
\(\textit{Ophiocordyceps xuansonae}\) a novel species of genus \(\textit{Ophiocordyceps}\) in Vietnam
Authors: Viet Nguyen Dinh , Lam Truong Xuan , Lam Duong Minh
Published: March 2023

The Ophiocordyceps is an important globally distributed genus that includes over 239-recorded species. Many species of the genus are famous for their significance in ecology, agriculture and pharmaceuticals. There have been 12 species of genus Ophiocordyceps found in Vietnam. In this study, the samples of Ophiocordyceps parasitizing the larva of order Lepidoptera at Xuan Son National Park in Phu Tho province were collected and characterized using both morphology and molecular analyses. The morphology comparison and ITS sequence analysis revealed that the fungus belongs to a new species of Ophiocordyceps. The paper presents the morphological and molecular description of the species.
Bacterial diversity in the sediments of three lagoons in Central Vietnam
Authors: Thi Hong Tran , Viet Cuong Pham , Van Phuong Nguyen
Published: March 2023

The prokaryotic community in sediment plays an important role in the nutrient cycles of lagoon ecosystems. However, the diversity of microbiota in sediments of Vietnamese lagoons has not been discovered. In this study, sediment samples from three lagoons in Central Vietnam were collected. The microbial community structure in the sediments was determined using Illumina sequencing of 16S rRNA at V3V4 regions. Mother software was used to analyze the data and identify the Operational Taxonomic Units (OTUs). Proteobacteria, Firmicutes, Campilobacterota, and Bacteroidetes were the major phyla in three lagoons, while Fusobacteria, Verrucomicrobia, Acidobacteria, Actinobacteria, and Chloroflexi were the minor. These groups of bacteria have been reported to be involved in organic metabolism cycles in sediments. Tam Giang lagoon showed more diversity in species composition when compared with Nai and Thi Nai lagoons. Class Clostridia were predominant in Tam Giang sediment (46%), which may indicate the presence of organic sewage in the environment. Thi Nai and Nai lagoons witnessed the significant presence of Lactobacilales and Vibrionales. While Vibrionales is an indicator of urban pollution, Lactobacilales and other groups of phylum Actinobacteria were potential materials for the screening of natural antibiotics.
CURRÍCULO
Authors: Lopes Quenizia Vieira , Tiroli Luiz Gustavo , Santos Adriana Regina de Jesus
Published: March 2023

O objetivo deste artigo consiste em discorrer sobre as principais concepções de currículo no cenário educacional a partir de quatro correntes teóricas-metodológicas distintas, quais sejam, o currículo Humanista, o currículo Acadêmico, o currículo Tecnológico e o currículo Reconstrucionista Social. Como percurso metodológico, trata-se de uma abordagem qualitativa, em que se adotou a pesquisa documental. Nas considerações finais, tem-se que o currículo não é campo de neutralidade epistemológica, ao contrário, é espaço de embate e tensões. Da análise, constatou-se que o currículo Reconstrucionista Social se revela mais comprometido com uma educação crítica e emancipatória, tendo em vista que visa instrumentalizar o sujeito com o acervo teórico-científico-cultural elaborado pela humanidade ao longo das quadras históricas, um currículo sócio-historicamente situado com vistas à humanização do sujeito.
La iglesia de los Jesuitas en Cusco como un modelo para la arquitectura de la región
Authors:   Cátedra de Historia del Arte de Universidad de Lodz Instituto Polaco de Investigación del Arte Mundial, Kubiak Ewa
Published: March 2023

At the end of the first half of the 17th century, a “European” character of Peruvian architecture was loosened. In 1650, an earthquake in Cusco destroyed existing buildings and, as the result, proved to be an impetus for building movement intensification. One of a few buildings which were not destroyed was a still unfinished Cusco cathedral, which later played a unique role in baroque architecture development in Peru. The temple was undoubtedly one of the first productions which could be associated with a baroque style. However, without diminishing the significance of the object, it is worth emphasizing other (not less important) sources of baroque architecture in the region. Another temple that undoubtedly influenced the shaping of a new trend in local building was a Jesuit church in Cusco. Mentioned as an important object for Peruvian architecture of the colonial period, it is usually treated as an element in the sequence of baroque architecture development in Peru. It is worth emphasizing the role that the temple played in creation of certain architectural models, which were present in Peruvian building of the late 17th and 18th centuries. Three analysed elements are: a facade composition (influence on the architecture of Cusco: San Pedro, Nuestra Señora de Belén, San Sebastián and the region – temples in Ayaviri, Asillo, Mamara, Huaquira, Puno); a design, a spatial layout and a structural system (similarity to a Jesuit church in Cusco of the temples of San Pedro in Cusco, San Pedro in Juli, Santiago de Pomata, Pisco); decorative-ornamental motifs – towers’ finials (San Pedro in Cusco) or columns’ decoration (Santa Cruz in Juli).
La dinámica cultural de una sociedad mediante los procesos de constitución y desintegración del territorio benedictino fluminense (1590–1922)
Authors:   Patrimonio del Monasterio de San Benito de Rio de Janeiro, Universidado do Estado do Rio de Janeiro, Fragoso Mauro Maia
Published: March 2023

Thanks to Edith Stein’s phenomenology, philosophy (including philosophy of culture) cannot be perceived as a static knowledge, unconnected with other fields of life and science. Based on such an assumption, research on cultural dynamics associated with functioning of the Benedictine order, which is presented in this article, has been divided according to three theoretical problems. One of them is the appearance of Benedictines (the first ones in Brazil) in Rio de Janeiro state, treated not only in literal, physical sense, but also as a spiritual phenomenon. The next part focuses on territorial borders – the area belonging to the order and connected with its functioning. It describes donations which contributed to the creation of cohesive area of the order’s properties as well as its activity. The last aspect that enables depiction of Benedictines’ presence in a social as well as territorial and cultural context is existence and functioning of the house of slaves (la casa de esclavos benedictina fluminense). What is particularly worth describing in this respect is a specific relationship between “a master” and “a slave” (señor y siervo) and an opportunity for individual development of some slaves in accordance with their interests, as was the case of a master of painting, Antonio Teles, or organists, Matias (known only by his first name) and José Campistas. Without emphasizing a relationship between human actions and the area of a social group’s activity, it would be impossible to point at the contribution of an institution to the heritage of the region to which it belonged. Dynamic presence of the order is illustrated with photos of São Bento church as well as a Benedictine monastery in Rio de Janeiro, being one of the most distinguished monuments of the metropolis, which is not only the evidence of bygone splendour, but also a centre of present Benedictine activity
La imagen colonial neogranadina y su aurea mediocritas
Authors:   Universidad de Buenos Aires Investigador Instituto de Investigaciones Sobre el Patrimonio – IIPC UNSAM, Rey-Márquez Juan Ricardo
Published: March 2023

The history of colonial art in Colombia is based on the idea of material poverty. This idea worked as a founding directive that conditioned historical perspective to a captatio benevolentiae exercise. As a consequence historians tried to explain that creative and material inferiority from a formalist paradigm, leaving unsolved many other historical problems. This essay attempts to unveil some of the theories underneath this historical perspective, analyzing some of the main New Grenade researchers.
Art Déco en la arquitectura Colonia Hipódromo Condesa, Cd. de México–Ciudad de Puebla: estudio comparativo
Authors:   Facultad de Arquitectura, Benemérita Universidad Autónoma de Puebla, Nochebuena Maria Cristina Valerdi , Oliver Jorge Sosa ,   Facultad de Arquitectura, Benemérita Universidad Autónoma de Puebla, Hernández Julia Judith Mundo ,   Universidad de las Américas Puebla – UDLAP
Published: March 2023

Art Deco was the largest decorative style of the 1920’s and perfect expression of extravagant Paris during that decade. It emerged as a force opposing the historicist academic trend, both in architectural and industrial design that expanded globally and despite the opinions and being ignored by researchers and architecture historians. This paper aims to show through comparative photographic coincidences and discrepancies in two different geographic locations in Mexico, and the features demonstrated in Art Deco style in architecture as a response to meet the needs of architectural spaces, emphasizing housing (among others) for the middle class that developed in that historical moment, as a result of questioning about what strategy would meet its formal characteristics. Formally structured according to the following content: Introduction, background, Art Deco architecture in Mexico, in the Colonia Hipordromo-Condesa and in the city of Puebla concluding with the photographic comparison showing the similarities regarding this style.
Rusya'nın 2014 Yılı Kırım'ı İlhakının Avrupa Birliği Ülkelerinin Askeri Harcamalarına Etkisi
Authors: ÖZCAN Oğuz , OZCAN Yunus
Published: March 2023

NATO’nun koruma şemsiyesi altındaki ülke sayısı en son 2020'de Kuzey Makedonya’nın katılımı ile 30’a yükselmiştir. Rusya’nın yayılmacı politikalarına karşı bu koruma avantajdan yararlanmak isteyen Ukrayna, Gürcistan, Bosna Hersek, İsveç ve Finlandiya’da üyelik müzakerelerini sürdürmektedir. 2014 yılında Rus silahlı birlikleri Ukrayna’nın Kırım bölgesini ilhak etmiş fakat bu durum Birleşmiş Milletler ve Avrupa Birliği gibi uluslararası kuruluşlar tarafından hiçbir zaman tanınmamıştır. NATO’ya üyeliğin önemi altı üyesi dışında hepsi NATO üyesi olan Avrupa Birliği ülkeleri için Rusya-Ukrayna arasında yaşanan gerilimlerde bir kez daha ortaya çıkmıştır. Rusya 2022 yılının Şubat ayında Ukrayna’nın Herson, Zaporijya, Donetsk ve Luhansk bölgelerini kapsayan daha geniş bir işgal harekâtını başlatarak bölgedeki gerilimi üst bir noktaya taşımıştır. Rusya’nın son dönem batıya doğru yayılmacı politikaları ve süregelen işgal hareketleri Avrupa Birliği’ni teşkil eden 27 ülke için milli savunmaları açısından riskleri artırmış ve neticesinde devlet bütçelerinden savunma harcamalarına ayrılan paylarını değiştirmelerini zorunlu kılmıştır. Birlik üyesi ülkeler güvenlik kaygılarını bertaraf edebilmek için savunma harcamalarını artırmışlardır. Bu çalışma ile öncelikle Rusya-Ukrayna arasında yaşanan gelişmeler tarihsel bir süreç içerisinde ele alınmakta ve sonrasında Avrupa Birliği’ne üye ülkelerin savunma amaçlı yaptıkları harcamaların yaşanan gelişmelere karşı seyri incelenmektedir. Çalışmada Kırım’ın ilhak edildiği tarih olan 2014 yılının etkilerinin daha belirgin hale gelebilmesi için analiz periyodu 2007-2014 ve 2014-2021 dönemleri olarak ayrıştırılmıştır. SIPRI veri tabanından elde edilen veriler ile Avrupa Birliği ülkelerinin 2007-2021 dönemi için askeri harcama gelişmeleri incelenmektedir. Çalışma bulgularına göre Avrupa Birliği ülkelerinin toplam askeri harcamaları 2007 yılında yaklaşık 213 milyar dolar iken 2014 yılında bu tutar 208 milyar seviyesine gerilemiştir. 2007-2014 periyodunda sadece 7 ülke askeri harcamalarını çok küçük oranlarda da olsa artırmıştır. 2014 deki ilhaktan sonra tüm üye ülkelerin askeri harcamalarını artırması ile 2021 yılına gelindiğinde Avrupa Birliği’nin toplam harcama tutarı yaklaşık 49 milyar dolar artarak 257 milyar doları geçmiştir. 2014-2021 döneminde birlik üyesi olarak harcamalarını oransal en çok artıran ilk üç ülke sırasıyla; Litvanya (%191), Letonya (%180) ve Macaristan (%130) olmuştur.
Um sistema de recomendação de rotas turísticas baseado em filtragem colaborativa
Authors: Santos Suzanne Loures , Durão Frederico Araújo
Published: March 2023

Resumo Planejar uma viagem, seja como turista ou a trabalho, pode não ser uma tarefa simples. Comprar passagens, encontrar acomodações disponíveis, selecionar lugares para conhecer, todo esse processo pode ser muito exaustivo considerando a quantidade de plataformas online que oferecem serviços no âmbito turístico e a sobrecarga de informações em buscadores na Web. Sistemas de Recomendação entram nesse contexto, para filtrar as informações e sugerir dados relevantes para o usuário. Este artigo propõe um sistema de recomendação de rotas turísticas, que visa auxiliar um viajante a encontrar pontos turísticos relevantes de acordo com suas preferências e interesses.
Virtual tools in the concept of reading of future teachers: a lexical exploration
Authors: Ibanez Ester Trigo , Díaz Inmaculada Clotilde Santos
Published: March 2023

Abstract New forms of reading have emerged recently, and virtual tools and environments have been developed to promote reading. Initial teacher training must be up to date to train good mediators. Therefore, this research analyses the presence of digital tools in the concept of reading of future teachers. The data has been collected through a lexical availability test to explore the centre of interest “Reading” and a sociodemographic questionnaire with questions related to reading and knowledge of languages. 520 students from the degrees in Early Childhood and Primary Education at the University of Malaga have participated. Dispogen has been used to process the available lexicon and the SPSS package has been used for the statistical analysis. In addition, clusters have been obtained from the lexicon related to digital tools using the DispoGrafo tool. The results show a motivation to read on social networks and a rootedness of the lexicon referred to digital media: e-book, Kindle, specifying format: PDF, Word, and type of reading: digital review, Academic Google, but they do not demonstrate a lexical domain for the formation of new readers.
The Concept of Hydroecosystems' Health (a Review)
Authors: Gandziura V. P. , Afanasyev S. O. , Biedunkova O. O.
Published: March 2023

The comprehensive analysis of the "hydroecosystems' health" concept was carried out; various views on this concept were considered in view of modern approaches to the natural water bodies' state assessment. The application of this concept in the monitoring programs and national legislation regarding the water resources' protection and management was analyzed. The evolution of the concept of "hydroecosystems' health" and search for indicators of its diagnostics was shown. The generalization of the analyzed information enabled to suggest the original definition of the concept of "hydroecosystems health", including all its aspects.
A MODELING STUDY ON AMMONIA AND AMMONIA/HYDROGEN KINETICS FOR GAS TURBINE ENGINES
Authors: Bedick Clinton , Tulgestke Andrew , Strakey Peter
Published: March 2023

The use of ammonia as a fuel source in gas turbine engine power cycles represents an attractive means to decarbonize the energy sector due to higher energy density and achieving liquid state at far lower pressures compared to pure hydrogen. However, due to low flammability and a propensity for high NOx emissions, its use is not without challenge. A number of zero- and one-dimensional modeling tools were utilized to study the combustion characteristics of ammonia and ammonia/hydrogen mixtures, examining basic fundamental properties such as laminar flame speed, variability among existing chemical kinetic mechanisms, and considering the use of two-stage rich-lean combustion strategies to
achieve low NOx emissions.
Experimental study on uniaxial compression of granite under real-time loading at designated low-temperature conditions
Authors: Zhang Yi-Feng , Zhang Fan , Lv Dun-Bo , Ding Xiang
Published: March 2023

A low temperature and the degree of saturation have important influence on the mechanical properties of rock surrounding cave-type underground liquefied natural gas storage. Uniaxial compression tests were carried out on dry and saturated granite under different real-time loadings at designated low-temperature conditions (25, 0, −20, −40, −50 and −60°C). The porosity and microstructure were then observed by nuclear magnetic resonance spectroscopy and scanning electron microscopy. The results show that with the decrease in temperature, the uniaxial compressive strength (UCS) and porosity of both dry and saturated granite monotonically increase, while the elastic modulus undergoes an increase–decrease transition and finally stabilises. At the same temperature, the UCS and elastic modulus of dry granite are generally greater than those of saturated granite. The reinforcement in the UCS and elastic modulus is caused by cold shrinkage, while the degradation in the elastic modulus, particularly for saturated granite, is attributed to freezing damage below 0°C. The results of this study can provide technical support for the long-term stability analysis and evaluation of underground cavernous liquefied-natural-gas-storage reservoirs.
Mechanical behaviour of grouted sands with acrylates and polyurethane resins
Authors: Spagnoli Giovanni , Collico Stefano , Tintelnot Götz
Published: March 2023

Chemical grouting is a technique where solution-based binders are used to improve both mechanical and hydraulic properties of the soil or rocks. The following research study shows an extensive laboratory programme where a polyurethane (PU) and an acrylate (AC) were grouted in a tertiary sand under different water contents and relative density, with different gelling time and grouting conditions. Unconfined compressive strength, splitting tests, triaxial tests and creep tests on the grouted materials were conducted. A statistical interpretation considering the kernel probability density function was performed in order to understand the interdependency of the changing parameters. In general, PU-consolidated samples provide higher mechanical properties with respect to ACs; however, the effects and the dependency on the geotechnical base parameters are different.
Autoexamen de mamas en estudiantes de una Universidad Pública del Caribe Colombiano
Authors: Díaz Cárdenas Shirley , Rodríguez Rodríguez Adrián , Arrieta-Vergara Katherine
Published: March 2023

Introducción: el autoexamen de mamas (AEM) es considerado el método más relevante, simple, asequible para prevenir y diagnosticar tempranamente cáncer de mama. Objetivo: Evaluar conocimientos, actitudes y prácticas sobre autoexamen de mama en universitarias del área de la salud. Métodos: Estudio de corte transversal realizado en 400 estudiantes de sexo femenino de una universidad pública. Se aplicó cuestionario anónimo ad-hoc de auto reporte, que incluía variables sociodemográficas y relacionadas con conocimientos, actitudes y prácticas sobre AEM. Datos analizados a partir de proporciones, regresión de Poisson estimando razones de prevalencias y asociaciones con intervalo de confianza de 95%. Resultados: 55,7%, 51,0% y 54,5 % presentaban adecuados conocimientos, actitudes y prácticas hacia AEM, respectivamente. En análisis multivariado el modelo que mejor explica conocimientos inadecuados fue ser adolescentes (RP=1,36), procedencia rural (RP=1,30), estudiar en programas no relacionados con AEM (RP=1,92) y consumir alcohol (RP= 1,28); actitudes inadecuadas: pertenecer a programas no relacionados con AEM (RP=1,44) y consumir alcohol (RP=1,48) y prácticas inadecuadas con ser adolescente (RP= 1,74) y pertenecer a programas no relacionados con AEM (RP=1,37). Conclusiones: Conocimientos, actitudes y prácticas inadecuadas sobre AEM en universitarias se encuentran asociados con edad, procedencia, consumo de alcohol y estudiar en programa académico no relacionado con AEM, ofreciendo luces específicas a intervenir desde la promoción en salud.
Prototipo de alimento funcional con ingredientes asociados a la disminución de los síntomas de la gastritis en adultos.
Authors: Zapata Daniela , Nuñez Merizalde Maria Antonia , Zuluaga Arroyave Natalia
Published: March 2023

La gastritis es una inflamación aguda o crónica de la mucosa gástrica, que se ha relacionado con infección con Helicobacter pylori (H. pylori), el sobre uso de antiinflamatorios no esteroideos, drogas, alcohol, tabaco, entre otros, llegando a producir síntomas como dolor localizado en el epigastrio o dispepsia, que largo plazo y en compañía de hábitos de vida no saludable, hay mayor riesgo de desarrollar cáncer gástrico. Por lo tanto, el objetivo general de este artículo fue desarrollar un prototipo de alimento funcional con ingredientes asociados a la disminución de los síntomas de la gastritis en adultos; Métodos: proyecto de innovación de prototipo de alimento que se basó en validación de información científica sobre alimentos funcionales relacionados con disminución de síntomas de la gastritis. El prototipo fue validado mediante pruebas sensoriales a panel experto y consumidor y desarrollo del modelo CANVAS; Resultados: se utilizaron Aloe Vera y Caléndula como ingredientes funcionales incluidos en dos bebidas de sabores fresa-mora y mango, encontrando que la primera tuvo una mayor aceptación y calidad sensorial tanto con panel experto como consumidor; Conclusiones: se obtuvo un prototipo de alimento con características sensoriales aceptadas, con los ingredientes funcionales caléndula y Aloe Vera que han sido relacionados en el público en general y por la evidencia científica para el manejo de los síntomas de la gastritis.
Impact of the COVID-19 pandemic on Muslim older immigrants in Edmonton, Alberta: A community-based participatory research project with a local mosque
Authors: Rehmani Amyna Ismail , Abdi Khadija , Mabrouk Esra Ben , Zhao Tianqi , Salami Bukola O. , Jones Allyson , Tong Hongmei , Salma Jordana
Published: March 2023

Objective

Older Muslim immigrants experience multiple vulnerabilities living in Canada. This study explores the experiences of Muslim older adults during the COVID-19 pandemic to identify ways to build community resilience as part of a community-based participatory research partnership with a mosque in Edmonton, Alberta.

Methods

Using a mixed-methods approach, check-in surveys (n = 88) followed by semi-structured interviews (n = 16) were conducted to assess the impact of COVID-19 on older adults from the mosque congregation. Quantitative findings were reported through descriptive statistics, and thematic analysis guided the identification of key findings from the interviews using the socio-ecological model.

Results

Three major themes were identified in consultation with a Muslim community advisory committee: (a) triple jeopardy leading to loneliness, (b) decreased access to resources for connectivity, and (c) organizational struggles to provide support during the pandemic. The findings from the survey and interviews highlight various supports that were missing during the pandemic for this population.

Conclusion

The COVID-19 pandemic exacerbated the challenges associated with aging in the Muslim population and contributed to further marginalization, with mosques being sites of support during times of crises. Policymakers and service providers must explore ways of engaging mosque-based support systems in meeting the needs of older Muslim adults during pandemics.
Diffusion of digital technologies in the face of external shocks: The case of the COVID-19 pandemic
Authors: Shcherbakov Roman , Privorotskaya Sofya , Vishnevskiy Konstantin
Published: March 2023

This paper investigates the impact of external shocks on the spread of digital technologies. Using the example of the COVID-19 pandemic, we identify and describe four patterns that reflect the uneven response of different digital technologies to external conditions undergoing transformation. The patterns differ in both the magnitude of the pandemic’s impact and the timing of the resulting effects. Video conferencing, business continuity and telemedicine services showed a dramatic increase in demand at the beginning of COVID-19 and a gradual decline in the later stages. A more moderate response in the early weeks of the pandemic is typical of e-commerce and online entertainment. Delayed effects are seen in digital logistics services and digital currencies, which reacted much later than other technologies. Finally, a slow decline in significance after the pandemic began has been observed for biometrics and cybersecurity technologies. Similar patterns may describe the transformation of the spread of digital technologies not only under the influence of COVID-19, but also in the face of dramatic economic and social changes of other origins.
Cas9 RNP nucleofection (CD34+ HSPCs) v2
Authors: not provided gregoire.cullot
Published: March 2023

Protocol for nucleofection of human HSPCs with Cas9 RNP.
DISCOVER-Seq: MRE11 ChIP Seq v2
Authors: van de Venn Lilly
Published: March 2023

Genome editing using nucleases such as CRISPR-Cas induces programmable DNA damage at a target genomic site, but can also affect off-target sites. We develop a powerful assay for the unbiased identification of off-target sites that we term DISCOVER-seq. This approach takes advantage of the recruitment of endogenous DNA repair factors for genome-wide identification of Cas-induced double strand breaks. One such factor, MRE11, is recruited so precisely to a double stranded break that nuclease cut sites can be determined with single-base resolution. DISCOVER-seq is applicable to multiple types of Cas nucleases and provides an unprecedented molecular picture of events that precede repair of the affected sites. DISCOVER-seq furthermore detects off-targets in cellular models and tissues.
Hashimoto Tiroidit’i ile Papiller Tiroid Karsinom Birlikteliği ve Prognoza Etkileri
Authors: CEYRAN Ayşe Bahar
Published: March 2023

Tiroidit, tiroid glandının inflamasyonu ile karakterize, çeşitli hastalıkları içeren genel bir terimdir. Hashimoto tiroiditi, en sık görülen otoimmun tiroid
hastalığıdır ve son yıllarda insidansı giderek artmaktadır. Papiller tiroid kanseri ise en sık görülen tiroid kanseri olup Hashimo tiroiditi zemininde genel
popülasyona göre daha sık görülmektedir.
Hashimoto tiroiditi ile papiller tiroid karsinomu arasındaki ilişki ilk olarak 1955 yılında Dailey ve ark tarafından ortaya atıldığından beri bununla ilgili
tartışmalar ve araştırmalar hala devam etmektedir. Hashimoto tiroiditi ve papiller tiroid karsinomu birlikte görülme insidansı literatüre göre %0.5 ile %41.4
arasında değişmekte olup ortalama yaş daha düşük bulunmuştur. Hashimoto tiroiditi ve papiller tiroid karsinom birlikteliğinin koruyucu bir etki gösterdiği,
Hashimoto tiroiditi ile birlikte olan papiller tiroid karsinomunun daha az agresif, tümörün daha küçük ve daha sıklıkla multifokal olduğu, daha az lenf nod
invazyonu gösterdiği bildirilmiştir. Hashimoto tiroiditi zemininde, multifokal alanlarda izlenen, displastik tirosit gruplarındaki papiller tiroid karsinomu
ilişkili gen aktivasyonları, Hashimoto tiroiditi-papiller tiroid karsinom birlikteliği ve multifokaliteden sorumlu tutulabilir.noz, Tiroidit.
Impact of COVID-19 on lifestyles related etiquette among nursing staff in India: a cross sectional descriptive e-survey
Authors: Kalal Nipin , K Sharma Suresh , Rana Nimarta , Kumar Ashok
Published: March 2023

Objective. To analyze the impact of COVID-19 pandemics on lifestyle-related etiquettes like eating, physical activity, and sleep behavior among nursing staff in India.   

Methods. A cross sectional descriptive E-survey was conducted among 942 nursing staff. The validated electronic survey questionnaire was used to assess the changes in lifestyle-related etiquette before and during COVID-19 Pandemic. 

Results. A total of 942 responses (mean age 29.01±5.7years) were collected, 53% of the respondents were men. A slight decline in healthy meal consumption pattern (p<0.0001) and a restriction of unhealthy food items were observed (p<0.0001), and also reduction in physical activity coupled with decreased participation in leisure-related activities was seen (p<0.0001). The stress and anxiety slightly increase during COVID–19 pandemics (p<0.0001). Additionally, social support extended by family and friends to maintain healthy lifestyle-related behaviors also significantly decreased during COVID-19 PANDEMIC pandemics compared to before (p<0.0001). Although the COVID-19 Pandemic slightly reduced the intake of healthy meals and deterred participants from consuming unhealthy food, this this may have led to individual weight loss.

Conclusion.  In general, there was a negative impact on, lifestyle like diet, sleep and mental health was observed. A detailed understanding of these factors can help to develop interventions to mitigate the harmful lifestyle-related etiquette that has manifested during COVID-19 Pandemic.
Nursing care for the transgender population in primary health care: an integrative review
Authors: Carneiro Chagas Manoella Alves , Dos Santos Adriano Maia , Neves de Jesus Naila
Published: March 2023

Objective. To describe the care provided to the transgender population by nursing in Primary Health Care (PHC).

Methods. Integrative literature review performed in the Virtual Health Library (VHL), Medline/PubMed and Web of Science (WoS) databases without a pre-established time frame, using the descriptors “transgender persons”, “gender identity”, “nursing care” and “primary health care”.

Results. Eleven articles published between 2008-2021 were included. They were categorized as follows: Embracement and healthcare; Implementation of Public Health Policies; Weaknesses in academic training; Barriers between theory and practice. The articles showed a limited scenario of nursing care for the transgender population. The scarcity of research focused on this theme is an important sign of how care has been incipient or even non-existent in the context of PHC.

Conclusion. Structural and interpersonal stigmas materialized in discriminatory and prejudiced practices perpetrated by managers, professionals and health institutions constitute the greatest challenges to be overcome for comprehensive, equitable and humanized care provided to the transgender population by nursing
Theoretical Reviewing Of Overlapping Consensus In The Context Of Abortion Debate
Authors: DOĞAN Mehmet Akif
Published: March 2023

Since the beginning of the late modern era, modern constitutions have been trying to keep both group rights as minority rights and individual rights. But, in some cases, it is still ambiguous if an action or a phenomenon must refer to individual rights or group rights. Abortion discussions, with regard to political rights, are one example of these ambiguous cases. In this context, whereas Liberal view tends to regard abortion as individual rights of a woman, Communitarian view can be against it by pointing out the right to life and this case may lead to a kind of liberal constitutional crises. This article gains importance as such constitutional crises still emerge even nowadays. John Rawls’s theory of overlapping consensus in Political Liberalism tries to solve these political conflicts that emerged in liberal constitutions by prioritizing public reason. This article conceptionally aims to examine Rawls’s theory in terms of prioritization and value relativity in abortion discussions. The method of article is hermeneutics. In order to extend the universe of the discussion, some important thinkers such as Immanuel Kant, Isaiah Berlin and John Gray, who have related studies on the topic, were included. In conclusion, it is asserted that Rawl’s theory is weak both practically and theoretically as to the principle of utilitarianism violates the rights of communitarians.
Perspectiva de Género y Acceso a puestos de Responsabilidad en Instituciones Sociosanitarias desde el Trabajo Social
Authors: Morcillo-Martínez Juana Maria , Martinez-Salvador Isabel Maria , Ochando-Ramirez Maria Victoria
Published: March 2023

A partir de la construcción social del género se establecen estereotipos y roles diferenciales para cada sexo, los cuales generan situaciones de discriminación y desigualdad para las mujeres. Esta cuestión se materializa en todos los ámbitos de la vida, incluido el laboral, y trae consigo una diferente valoración entre las funciones que han de desarrollar los hombres frente a las que deben desarrollar las mujeres. Este estudio se plantea el objetivo de analizar cuáles son las cuestiones clave que dificultan a las mujeres ocupar puestos de responsabilidad y liderazgo en las instituciones sociosanitarias. Para ello, hemos utilizado una metodología cualitativa, realizando entrevistas a veinticinco Trabajadoras Sociales, que desarrollan su praxis profesional en entidades de ámbito público, privado y tercer sector de diferentes provincias de la zona de Andalucía Oriental (España). Los resultados señalan que, pese a que la situación de las mujeres ha mejorado en los últimos tiempos, la realidad es que siguen existiendo barreras y obstáculos que impiden hablar de equidad para avanzar hacia la igualdad real, el emprendimiento y liderazgo desde la perspectiva de género en las instituciones sociosanitarias.
Generation Z and Intention to Travel: Effects of the Perception of COVID-19
Authors: Jiménez-García Mercedes , Ruiz-Chico José , Peña-Sánchez Antonio-Rafael
Published: March 2023

Previous studies have investigated the effects of the coronavirus pandemic on different aspects of tourism behaviour. However, research on a specific generational group, Generation Z, is still limited. This exploratory study aims to examine, for members of this generation, the effect of the perceived risk of COVID-19 and non-pharmaceutical interventions (NPI) on their intention to travel and, in turn, whether this intention influences their willingness to pay extra to benefit from additional safety measures. With this approach, a Structural Equations methodology has been applied based on 629 surveys received and using SmartPLS 3.0 to analyse them. The results showed that the higher the travel intention of Gen Z, the higher the individual's willingness to pay for additional security measures, the perceived risk of COVID-19 positively influences the NPI taken and in turn, these NPI influence a higher travel intention. However, the authors have not found a significant effect between the perceived risk and Gen Z's intention to travel. Finally, they discuss the theoretical and practical implications of the results, providing suggestions for the recovery of Gen Z tourism after the pandemic.
Change in the spectrum of detected mutations in the DMD gene depending on the methodological capabilities of the laboratory
Authors: Zinina E. V. , Bulakh M. V. , Ryzhkova O. P. , Shchagina O. A. , Polyakov A. V.
Published: March 2023

Background. Duchenne muscular dystrophy (DMD) is a severe, progressive form of muscular dystrophy that occurs in children between one and three years of age. The disease is mainly characterized by weakness of the proximal muscles, which leads to difficulty in movement, and ultimately to complete disability. Becker muscular dystrophy (BMD) is a milder allelic form of the disorder characterized by late onset and slow progression. The cause of the development of DMD/BMD is mutations in the DMD gene, leading to a deficiency in the production of various isoforms of the dystrophin protein family. The most common mutations in case of DMD/BMD are gross deletions (55–65 %) and duplications (6–11 %) of one or several exons The remaining cases of DMD/BMD are due to small mutations (approximately 20–30 %). Depending on the methodological capabilities of the laboratory, the idea of the spectrum of mutations in the DMD gene changed, which is important in genetic counseling of patients and planning the therapy available today.

Aim. To analyze the spectrum of mutations in the DMD gene, including three time slices, depending on the methodological capabilities of the laboratory.

Materials and methods. We analyzed the spectrum of mutations in the DMD gene for a sample of 2957 patients admitted to the laboratory of DNA diagnostics of the Research Centre for Medical Genetics with a referral diagnosis of DMD/BMD. Depending on the time of treatment and the capabilities of the laboratory, patients were divided into three groups: 2008–2015, 2016–2018, 2019–2022.

Results. As a result of the study, the full range of mutations in the DMD gene was analyzed over three-time intervals, which makes it possible to get an idea of the distribution of mutation types in the sample among Russian patients. Regardless of the methodological capabilities of the laboratory, the spectrum of mutations in the DMD gene remains biased relative to world data. At the moment, there is a significant decrease in the proportion of extended deletions (50.7–59.6 %), while the proportion of extended duplications (11.8–17.2 %) and small mutations (23.2–35.0 %) increased. We assume that the main reason for such features of the spectrum is ethnic and population differences.

Conclusion. Duchenne/Becker muscular dystrophy (DMD/BMD) is the most common form of muscular dystrophy, accounting for more than 50 % of all cases. Determination of the spectrum of mutations provides an understanding of their frequencies, which in the future may help patients in the appointment of therapy specific to a particular type of mutation.