bluuebunny/crossref_metadata_2025 huggingface dataset:
Destination images of visitors attending to travel expo in key markets of Turkey
Authors: Altintas Volkan , Sirakaya-Turk Ercan , Bertan Serkan
Published: July 2021

The objective of the current study was to assess how the origin, education levels, gender, ages and income of expo visitors affected their perceptions of Turkey and what could be done to improve visitors’ perception of Turkey. Data were collected in three expos held in three countries via self-reported survey instruments. Survey instrument included scale items which probed people’s perceptions and images of Turkey along with other relevant variables. There were 264 Germans participants, 332 Dubains, and 94 Russians. Profiles of markets were analyzed using t-tests. The result of this study showed that demographic characteristics of participants affected their perceptions of the destination differently.
Peningkatan Ketrampilan Kreativitas Desain Grafis Digital Siswa SMU Menggunakan Aplikasi CANVA pada Ponsel Pintar
Authors:   Informatika, Fakultas Ilmu Komputer, Universitas Pembangunan Nasional “Veteran” Jawa Timur, Anggraeny Fetty Tri , Wahanani Henni Endah ,   Informatika, Fakultas Ilmu Komputer, Universitas Pembangunan Nasional “Veteran” Jawa Timur, Akbar Fawwaz Ali ,   Informatika, Fakultas Ilmu Komputer, Universitas Pembangunan Nasional “Veteran” Jawa Timur, Raharjo M. Ilham Prasetyo ,   Informatika, Fakultas Ilmu Komputer, Universitas Pembangunan Nasional “Veteran” Jawa Timur, Rizkyando Sandy ,   Informatika, Fakultas Ilmu Komputer, Universitas Pembangunan Nasional “Veteran” Jawa Timur
Published: July 2021

During the COVID-19 pandemic, teaching and learning activities must be carried out online from home. The development of technology today really helps the online teaching and learning process, there are many tools / software that can be used. Tools / software commonly used in online teaching and learning activities are Ms. Word, Ms. Power Point, and Virtual Lab. Another impact of technological developments coupled with pandemic conditions has led to more interactions between humans being carried out online through internet intermediaries on cellphones or computers. Currently cellphones do not only function as a medium of communication, some work that was previously completed using a computer / laptop can now be completed using a smart phone. So that cellphones can be used for more positive activities and support the teaching and learning process, sharing is carried out with students through sharpening design creativity through mobile applications on smart phones. In this activity, students hone graphic design skills using the CANVA application to support the teaching and learning process. The enthusiasm of students is quite high, as evidenced by the work produced in the form of personal profile designs, extracurricular activities and logos. Students can practice well the material presented. The school welcomes this activity, and wants to form an extracurricular Graphic Design at SMA Dharma Wanita so that it becomes a forum for student creativity in graphic design.
The Influence of pH and Temperature on Water as a Pressurized Fluid in the Extraction of Bioactive Myconutrients from Chaga Mushroom (Inonotus obliquus)
Authors: Abu-Reidah Ibrahim M. , Critch Amber , Manful Charles , Rajakaruna Amanda , Vidal Natalia Prieto , Pham Thu Huong , Cheema Mumtaz , Thomas Raymond
Published: July 2021

Mushrooms have long rich history in folk medicine, traditional and functional foods due to high content of dietary myco-nutrients. Currently, there is increased interest in finding appropriate food-grade green ex-traction systems capable of extracting these bioactive compounds from dietary mushrooms for applica-tions in various food, pharmacological or nutraceutical formulations. Herein, we evaluated a modified Swiss water process (SWP) method using alkaline and acidic pH at low and high temperature under pressurized conditions as a suitable green food grade solvent to obtained extracts enriched with my-co-nutrients (dietary phenolics, total antioxidants (TAA), vitamins, and minerals) from Chaga. Ultra-high performance liquid chromatography coupled to high resolution accurate mass tandem mass spectrometry (UHPLC-HRAMS-MS/MS) was used to assess the phenolic compounds and vitamin levels in the extracts, while inductively coupled plasma mass spectrometry (ICP-MS) was used to determine the mineral con-tents. Over twenty phenolic compounds were quantitatively evaluated in the extracts and the highest total phenolic content and antioxidant activity was observed at pH11.5 at 100°C. The most abundant phenolic compounds present in Chaga extracts included phenolic acids such as protocatechuic acid 4-glucoside (0.7-1.08µg/mL), syringic acid (0.62-1.18µg/mL), and myricetin (0.68-1.3µg/mL). Vitamins are being reported for the first time in Chaga. pH 2.5 at 100°C treatment shows superior effects in extracting the B vitamins whereas pH 2.5 at 60 and 100°C treatments were outstanding for extraction of total fat-soluble vitamins. Vitamin E content was the highest for the fat-soluble vitamins in the Chaga extract under acidic pH (2.5) and high temp. (100°C) and ranges between 50 to 175 µg/100g Chaga. Antioxidant minerals ranged from 85.94 µg/g (pH7 at 100°C) to 113.86 µg/g DW (pH2.5 at 100°C). High temperature 100°C and a pH of 2.5 or 9.5. The treatment of pH11.5 at 100°C was the most useful for recovering phenolics and antioxidants from Chaga including several phenolic compounds reported for the first time in Chaga. SWP is being proposed herein for the first time as a novel, green food-grade solvent system for the extraction of myco-nutrients from Chaga and have potential applications as a suitable approach to extract nutrients from other matrices. Chaga extracts enriched with bioactive myconutrients and antioxidants may be suitable for further use or applications in the food and nutraceutical industries.
Using a Product Life Cycle Cost Model to Solve Supplier Selection Problems in the High-Technology Company
Authors: Jwo Tao Yu , Shyuan Lin Yi , Shih Lee Hsuan , Shu Tu Chang
Published: July 2021

Using the PLCC advantages generates revenue and lowers costs more than might be anticipated. It ensures better decisions by using a more perfect and practical assessment of revenues and costs. Although the supplier selection (SC) product life cycle cost (SCPLCC) is an important consideration among corporations, SCPLCC problem has become associated with deciding how one supplier should be selected from possible alternatives. In this study, we applied two types of goal programming, multiobjective linear programming and revised multichoice goal programming to develop a PLCC-based concept to solve the SCPLCC problem and construct a decision-making tool for application to a case of supply chain management in a Taiwanese light-emitting diode company in the high-tech industry. Our study main contribution Company managers can easily use the two approaches of the SCPLCC model with different parameters to solve SCPLCC model problems. Finally, we comparing five models found RMCGP with weighted linear goal programming had an adequate effect for application to the PLCC concept for high-technology company; this cloud make company decision–makers focus on low PLCC and select better supplier.
Simultaneous Recording of the Uptake and Conversion of Glucose and Choline in Tumors by Deuterium Metabolic Imaging (DMI)
Authors: Veltien Andor , van Asten Jack , Ravichandran Niveditha , De Graaf Robin , De Feyter Henk , Oosterwijk Egbert , Heerschap Arend
Published: July 2021

: Increased glucose and choline uptake are hallmarks of cancer. We investigated if the uptake and conversion of [2H9]choline alone and together with that of [6,6’ 2H2]glucose can be assessed in subcutaneous tumors by deuterium metabolic imaging (DMI) after bolus administration of these compounds. Therefore tumors with human renal carcinoma cells were grown subcutaneously in mice up to ~0.5 cm3. Mice were anesthetized with isoflurane and IV infused in the MR magnet for ~20 sec with ~0.2 ml solutions containing either [2H9]choline (0.05g/kg) alone or together with [6,6’ 2H2]glucose (1.3g/kg). 2H MR was performed on a 11.7T MR system with a home-built 2H/1H coil using a 900 excitation pulse and 400ms repetition time. 3D DMI was recorded at high resolution (2x2x2mm) in 37 min or at low resolution (3.7x3.7x3.7mm) in 2:24 min. Absolute tissue concentrations were calculate assuming initial [HOD]=13.7mM. Within 5 minutes after [2H9]choline infusion its signal appeared in tumor spectra representing concentration increasing up to 0.3–1.2 mM and then slowly decreased or remained constant over 100 minutes. In plasma [2H9]choline disappeared within 15 minutes post-infusion implying that its tumor signal arises from tissue and not blood. After infusing a mixture of [2H9]choline and [6,6’ 2H2]glucose their signals were observed separately in tumor 2H spectra. Over time the [2H9]choline signal broadened, possibly due to conversion to other choline compounds, [[6,6’ 2H2]glucose] declined, [HOD] increased and a lactate signal appeared, reflecting glycolysis. Metabolic maps of all 2H compounds were reconstructed from high resolution DMIs. As choline infusion and glucose DMI is feasible in patients, their simultaneous detection has clinical potential for tumor characterization.
A Natural Degradant of Curcumin, Feruloylacetone Inhibits Cell Proliferation via Inducing Cell Cycle Arrest and a Mitochondrial Apoptotic Pathway in HCT116 Colon Cancer Cells
Authors: Chou Yu-Ting , Koh Yen-Chun , Nagabhushanam Kalyanam , Ho Chi-Tang , Pan Min-Hsiung
Published: July 2021

Feruloylacetone (FER) is a natural degradant of curcumin after heating, which structurally reserves some functional groups of curcumin. It is not as widely discussed as its original counterpart in previous studies and, therefore, its anti-cancer efficacy is investigated herein. This study focuses on the suppressive effect of FER on colon cancer, as the efficacious effect of curcumin on this typical cancer type has been well evidenced. In addition, demethoxy-feruloylacetone (DFER) was applied to compare the effect that might be brought on by the structural differences of the methoxy group. It was revealed that both FER and DFER inhibited the proliferation of HCT116 cells, possibly via suppression of the phosphorylated mTOR/STAT3 pathway. Notably, FER could significantly repress both the STAT3 phosphorylation and protein levels. Furthermore, both samples showed the capability of arresting HCT116 cells at the G2/M phase via the activation of p53/p21 and upregulation of cyclin-B. In addition, ROS elevation and changes in mitochondrial membrane potential were revealed, as indicated by p-atm elevation. The apoptotic rate rised to 36.9% and 32.2% after being treated by FER and DFER, respectively. In summary, both compounds exhibited an anti-cancer effect, and FER showed a greater pro-apoptotic effect, possibly due to the presence of the methoxy group on the aromatic ring.
Plants Metabolome Study: Emerging Tools and Techniques
Authors: Patel Manish Kumar , Pandey Sonika , Kumar Manoj , Haque Intesaful , Pal Sikander , Yadav Narendra Singh
Published: July 2021

Metabolomics is now considered to be a wide-ranging, sensitive and practical approach to acquire useful information on the composition of a metabolite pool present in any organism, including plants. Investigating metabolomic regulation in plants is essential to understand their adaptation, acclimation and defense response to environmental stresses through the production of numerous metabolites. Moreover, metabolomics can be easily applied for the phenotyping of plants; and thus, it has great potential to be used in molecular breeding and genome editing programs to develop superior next generation crops. This review describes the recent analytical tools and techniques available to study plants metabolome, along with their significance of sample preparation using targeted and non-targeted method. Advanced analytical tools, like gas chromatography-mass spectrometry (GC-MS), liquid chromatography mass-spectroscopy (LC-MS), capillary electrophoresis-mass spectrometry (CE-MS), fourier transform ion cyclotron resonance-mass spectrometry (FTICR-MS) and matrix-assisted laser desorption/ionization (MALDI) have speed up metabolic profiling in plants. Further, we deliver a complete overview of bioinformatics tools and plant metabolome database that can be utilized to advance our knowledge to plant biology.
Loop-Mediated Isothermal Amplification in Core-Shell Beads Assay for the Detection of Tyrosine Kinase AXL Over Expression
Authors: Sreejith Kamalalayam Rajan , Umer Muhammad , Singha Pradip , Nguyen Nhat-Khuong , Kasetsirikul Surasak , Ooi Chin Hong , Shiddiky Muhammad , Nguyen Nam-Trung
Published: July 2021

The upregulated expression of thyrosine kinase AXL has been reported in several hematologic and solid human tumors including gastric, breast, colorectal, prostate, and ovarian cancers. Thus, AXL can potentially serve as a diagnostic and prognostic biomarker for various cancers. This paper reports the first-ever use of loop-mediated isothermal amplification (LAMP) of the AXL gene as a diagnostic method for ovarian cancer. We demonstrated simple instrumentation toward a point-of-care device to perform LAMP. This paper also reports the first-ever use of core-shell beads as a microreactor to perform LAMP as an attempt to promote environmentally friendly laboratory practices.
Macrocyclic Tetramers – Structural Investigation of Peptide-Peptoid Hybrids
Authors: Herlan Claudine , Sonnefeld Anna , Gloge Thomas , Brückel Julian , Schlee Luisa , Muhle-Goll Claudia , Nieger Martin , Bräse Stefan
Published: July 2021

The determination of the three-dimensional structure is a key step for the identification of new targets as well as the rational design of bioactive compounds. Herein, we report the synthesis and the structural elucidation of novel tetrameric macrocycles. Measurements were taken in solid and solution states with the help of X-ray scattering and NMR spectroscopy. The investigations made will help to find diverse applications for this new, promising compound class.
OPINIONS AND KNOWLEDGE ABOUT EAR CROPPING AND TAIL DOCKING AT DOGS IN STARGARD CITY
Authors:   Department of Biotechnology and Animal Husbandry, West Pomeranian University of Technology in Szczecin, Poland, KARATYSZ Karla
Published: July 2021

Currently, ear cropping and tail docking are practised surgeries at veterinary clinics. These procedures have been around for centuries with first cases already performed in ancient Rome. The purpose of such body modifications is based on editing ear and tail shapes in a Since 1997, ear cropping and the tail docking is prohibited in Poland, with an exception for when animal’s life is endangered and depends upon it. This law also applies to other European countries and the rest of the world, including laws on crossing their boarders with pets recently subjected to this kind of surgery; all of which are regulated by adequate ruling bodies. The aim of this research study was to explode various opinions and level of knowledge on this topic of residents of Stargard city, as well as their personal position with regard to the ear cropping and tail docking at dogs. The research material was collected by direct survey and the selection of respondents was random. Achieved results explicitly pointed at predominating number of negative opinions of performing described surgeries on dogs.
MORPHOLOGICAL CHANGES IN THE TISSUES OF THE RABBIT KNEE JOINT DUE TO EXPERIMENTAL OSTEOARTHRITIS AFTER THE USE OF MESENCHYMAL STEM CELLS
Authors:   Department of Surgery and Pathophysiology named after acad. I.O. Povazhenko, National University of Life and Environmental Sciences of Ukraine, Kyiv, Ukraine, MALYUK Nikolai , DEMIANTSEVA Yuliia ,   Department of Surgery and Pathophysiology named after acad. I.O. Povazhenko, National University of Life and Environmental Sciences of Ukraine, Kyiv, Ukraine, KHARKEVYCH Yuriy ,   Department of Surgery and Pathophysiology named after acad. I.O. Povazhenko, National University of Life and Environmental Sciences of Ukraine, Kyiv, Ukraine, BOKOTKO Roman ,   Department of Surgery and Pathophysiology named after acad. I.O. Povazhenko, National University of Life and Environmental Sciences of Ukraine, Kyiv, Ukraine, MELNYK Oleg ,   Department of Animal Anatomy, Histology and Pathomorphology named after academician Vladimir G. Kas’janenko, National University of Life and Environmental Sciences of Ukraine, Kyiv, Ukraine, GRYZINSKA Magdalena ,   Institute of Biological Basis of Animal Production, Faculty of Biology, Animal Sciences and Bioeconomy, University of Life Sciences in Lublin, Poland
Published: July 2021

The purpose of the study was to investigate the regenerative processes in the knee joint of rabbits with experimental osteoarthritis after using of allogeneic bone marrow stem cells and a traditional treatment with the non-steroidal anti-inflammatory drug Meloxicam. For the experiment were used 27 male California rabbits (males). Three groups of animals were formed: a control group; the first experimental group treated by the traditional method; the second experimental group treated with allogeneic mesenchymal stem cells (MSC). Animals in the three groups were subjected to osteoarthritis of the knee joint by double injection of 3.44% retinol acetate into the joint cavity at a dose of 1 ml at intervals of 7 days. Tissue from the affected site was sampled for histological examination at 7, 14 and 28 days. The histological sections were stained with haematoxylin-eosin and examined under a microscope. It has been established that intra-articular administration of 3.5 × 106 cells of allogeneic MSCs in experimental osteoarthritis contributes to the restoration of the superficial layer of cartilage, as evidenced by the formation of columns of chondrocytes in the middle layer of articular cartilage and the appearance of isogenic groups of cartilage cells with basophilic cytoplasm in the matrix, uniform articular surface. The use of the traditional method of treating rabbits using the drug Meloxicam is accompanied by incomplete chondrogenesis: part of the chondrocytes is localized in typical chambers, in some cases chondrocyte chambers did not differentiate; articular cartilage had unequal thickness, cell placement was uneven.
An Evaluation of Adaptive Capability on Organizational Performance of Tier Two Commercial Banks in Kenya
Authors: Mweu Wambua Benjamin , Mung’ara Maria W.
Published: July 2021

Banking sector rivalry has escalated which can be attributed to many factors including innovation, new legislation, problems caused by a global financial crisis, government regulations, among others that have resulted in increased competition in the banking sector. The objective of this study was to evaluate the influence of adaptive capability on the organizational performance of tier two commercial banks in Kenya. The study found that the application of adaptive capabilities in commercial banks in Kenya is influenced by mainly customer demands, staff expertise and the prevailing market trends.  The study results show that there is a positive and statistically significant relationship between Adaptive Capability and performance in tier two banks. The study concluded that adaptive capability has a positive and significant relationship with performance in tier two banks. The research findings recommended that the employees should be fully involved in the decision-making process so that they can own up to the strategies being formulated by the top management.
Efektivitas Dakwah Melalui Media Sosial Di Era Media Baru
Authors: Zaini Ahmad , Rahmawati Dwy
Published: July 2021

Sesungguhnya dakwah merupakan tanggung jawab setiap orang, apapun itu pekerjaannya harus bisa menyampaikan pesan dakwah agar bisa diterima oleh khalayak atau masyarakat. Tentu dalam menyampaikan pesan dakwah harus ada cara yang efektif. Efektivitas dakwah melalui media sosial saat ini menjadi penelitian utama yang banyak dipelajari oleh para kalangan karena hal tersebut sangat penting untuk diketahui, supaya kita dapat mengukur sejauh mana tingkat keberhasilan kegiatan dakwah melalui media sosial. Penggunaan media sosial sebagai media atau sarana dakwah di era baru saat ini memang menjadi alternatif bagi para penceramah/dai/ustadz dalam melaksanakan aktivitas dakwahnya. Berbagai platform media baru pun digunakan untuk mendukung proses dakwah, menjadi sebuah bukti bahwa internet berperan penting dalam proses kegiatan dakwah. Oleh karena itu, peluang dakwah menjadi besar karena IPTEK saat ini berkembang pesat. Dakwah melalui internet akan menjadi alat yang akan berperan penting dalam proses meningkatkan, menyeimbangkan, dan memberikan arah hidup yang lebih baik. Maka dari itu dalam jural artikel ini penulis mencoba mengkaji tentang bagaimana tingkat efektivitas dakwah yang dilakukan melalui media sosial di era baru saat ini.
Konflik Sosial Kegamaan di Pati: dari Motif Teogenetis ke Sosiogenetis atas al Quran dan Hadis
Authors: Mukhamad Agus Zuhurul Fuqohak Mukhamad Agus Zuhurul Fuqohak Zuhurul
Published: July 2021

This article aims reveal the conflicting motives for understanding the coran and Hadith in Sundoluhur Pati Village, Indonesia. This article uses a phenomenological approach for looking through interviews with five charismatic peoples. This paper uses theory of motives and Bourdieu's theory of habitus, capital and arena. Motive theory is used to reveal the nature and characteristics of the problems, and Bouerdie's theory analyzes the developing problems in order to detect the modals used in arguing. The finding of the article is that the conflict began when the study of the Coran and Hadith with the books of al-Muwafaqat and al-I'tisham by Imam as-Syâthibi could be categorized as a theogenetic motif. The power desired by some figures and the community is a sociogenetic motive because of the community's push for religious leaders to return to old traditions.
PERAN SAHABAT DALAM PERIODISASI HADIS DAN IMPLIKASINYA TERHADAP TRANSMISI KEILMUAN PENDIDIKAN ISLAM
Authors: Rosyidah Aisyatur , Kholis Nur , Husna Jannatul
Published: July 2021

Periodisasi hadits menjadi bahasan penting dalam diskusi keilmuan Islam. Sebagai sumber kedua dalam Islam, secara otomatis hadits juga menerima kritik yang dilontarkan oleh para sarjana barat yang mendiskreditkan sumber ajaran Islam. Penelitian ini mengambil pemikiran Mustafa al-Azami, yaitu cendekiawan yang berupaya untuk mendudukkan kembali periodisasi hadits dari masa pencatatan hingga kodifikasi. Adapun metode pewartaan dalam periodisasi tersebut berimplikasi kepada landasan transmmisi keilmuan saat ini. Penelitian ini adalah penelitian kualitatif yang bersifat deskriptif-analitis, Hasil penelitian menunjukkan bahwa periodisasi hadits dari masa pencatatan hingga kodifikasi menimbulkan jejak metode dalam proses validitas atau kritik terhadap sanad dan matan hadits. Hal ini berimplikasi dalam penerapan terhadap transmisi keilmuan masa kontemporer, sebagaimana yang telah dipraktikkan jauh pada masa para sahabat. Metode para sahabat menandakan bahwa kegiatan literasi telah dilakukan pada masa Nabi SAW. Bahkan metode tersebut telah direfleksikan dengan kegiatan transmisi keilmuan masa kini. Hal ini menegaskan bahwa Islam dalam transmisi keilmuan hanya membawa kebenaran sebagai petunjuk bagi seluruh umat manusia.

[The Role of Friends in The Periodization of Hadith and Their Implications on The Transmission of Islamic Education Science. Periodization of hadits to be an important discussion in the discussion of Islamic scholarship. As a second source in Islam, hadits automatically also received criticsm by scholars of the western that discredit the source of the teaching of Islam. This study based the thingking of Mustafa al-Azami. He is a scholars who focus to but back the periodization of the hadits of the recording to the codification. As for the method of preaching in the periodization of the implications to the transmission of science at this time. This research is qualitative research which is descriptive-analytical. Result of the study is that the periodization of the hadits of the recording to the codification cause the trace method in the process of the validity or criticsm of sanad and matan of hadits. This has implications in the application to the transmission of scientific contemporary period, as has been practised of the companions. The method of the companions indicates that the literacy activities have been done since at the time of prophet Muhammad SAW. Even the method that has been reflected by the activities of transmission of knowledge of the present. This confirm that Islam in the transmission of scientific just bring the truth as guidance for all human.]
Knee Arthroplasty in Klippel-Trénaunay Syndrome with 3-Dimensional–Printed Patient-Specific Instruments
Authors: Wang Xiaohua , Zhang Ke , Yuan Liang , Sun Bin , Yang Bin
Published: July 2021

Case:

Using a multidisciplinary team approach, a cemented posterior-stabilized total knee arthroplasty was performed using 3-dimensional–printed patient-specific instruments (PSI) in a 34-year-old man with symptomatic end-stage knee osteoarthritis secondary to Klippel-Trénaunay syndrome (KTS). At 1-year follow-up, the patient was able to walk without pain and return to work.

Conclusion:

Knee arthroplasty is rare in patients with KTS. Compared with traditional instrumentation, PSI provides the benefit of minimal tissue dissection which can be advantageous in patients with altered anatomy such as KTS. Multidisciplinary cooperation is vital in terms of dealing with multiple comorbidities in KTS.
Development of Parsonage-Turner Syndrome After Interscalene Brachial Plexus Block Including 10-Year Follow-up
Authors: Parnes Nata , Dunn John C. , Perrine Jeff , Scanaliato John P.
Published: July 2021

Case:

A 22-year-old female patient demonstrated physical examination findings of Parsonage-Turner syndrome (PTS) 5 days after left shoulder arthroscopic surgery with interscalene brachial plexus block. The diagnosis was confirmed with electrodiagnostic testing 2 weeks after surgery. Symptoms resolved spontaneously within 2 years with full return-to-preinjury sport and job activity. These outcomes were maintained at the 10-year follow-up.

Conclusions:

PTS should be considered in the differential diagnoses for any postsurgical neurological variations after upper extremity surgery under regional anesthesia.
Urban Disaster Management in Government Communication Perspective
Authors: Jumansyah Jumansyah , Alaydrus Anwar , Budiman Budiman , Alamsyah Bebika
Published: July 2021

One indicator of the success of regional governance is the ability of local governments to provide security and comfort for people from natural and social disasters, thus through the authority and resources of the local government they are required to build horizontal and vertical communication in order to respond and provide alternative solutions to all potential disaster that can cause material or non-material loss to the community. Therefore, this study aims to explore disaster management in the perspective of government communication in Botang City. This study used a qualitative case study approach with interactive analysis, so it was found that government communication in Bontang City was built through territorial, program and business approaches. So that the community and the private sector are actively involved in the disaster management process through coordinated communication under the command of the local government. In addition, communication between the local government of Bontang City in disaster management is also continuously improved through active involvement of experts / experts, mass media, and community organizations / NGO / associations.
РАЗВИТИЕ МОНОГОРОДОВ В УСЛОВИЯХ МОДЕРНИЗАЦИИ ЭКОНОМИКИ
Authors: УГОЛЬНИКОВА О. , РИЗОВ А.
Published: July 2021

Развитие моногородов в условиях модернизации экономики России является важнейшим аспектом не только развития экономики страны, но и основой социальной стабильности в обществе и фактором регулирования внутренних миграционных потоков.
В статье рассматриваются различия экономического развития регионов, с учетом разных природных условия, обеспеченности инфраструктурой и ресурсами, дана классификация моногородов и сделан сравнительный анализ экономического развития регионов России.
Также в статье рассмотрены варианты стратегического развития регионов и моногородов с учетом трендов мировой экономики.
МЕНЕДЖМЕНТ И ИНЖИНИРИНГ ПРИ РЕШЕНИИ ПРОБЛЕМЫ ОЧИСТКИ ПИТЬЕВОЙ ВОДЫ
Authors: ДРОЗДОВ Г. , ЧУРИЛИН А.
Published: July 2021

Снабжение населения качественной питьевой водой в больших городах представляет серьезную научную и практическую задачу. С одной стороны, ужесточаются требования к качеству питьевой воды, подаваемой в системы централизованного водоснабжения. С другой стороны, существующие технологии не всегда могут справляться с поставленной задачей в силу различных причин. В мировой практике накоплен опыт разработки и применения различных технологий улучшения качества воды, подаваемой в водопроводную сеть. Однако в настоящее время все большее предпочтение отдается мембранным методам с большой надеждой на будущее ввиду невысокой стоимости, компактности, простоте обслуживания. В статье рассмотрены эффективные способы очистки питьевой воды.
LOGISTICS MANAGEMENT FOR SMALL AND MEDIUM-SIZED ENTERPRISES
Authors: Kuhan S.
Published: July 2021

Managing the logistics of small businesses at the regional level helps to create a competitive advantage of the territory by coordinating and integrating the functions, processes and activities of all participants in the logistics chain. The article deals with the interaction of logistics management systems for small enterprises that are part of the logistics system of the region.
FACTORS AND TRENDS OF DEVELOPMENT OF THE BELARUSIAN-SYRIAN ECONOMIC RELATIONS
Authors: Safwan Mashi Ammar
Published: July 2021

Thearticleisdevotedtothestudyofconceptualfoundationsandthedeterminationof directions for increasing the development efficiency of Belarusian-Syrian economic relationships. According to the results of the study, it was found that bilateral economic relationships and their effectiveness depend on the characteristics of the development of national economies, and the potential of export-import relations between countries depends on the state of the national economy, the scale of the national economy, industry specifics, etc. Projects of bilateral cooperation in the industrial sphere were proposed: a project of organization of the import of Syrian phosphates by Gomel Chemical Plant OJSC in exchange for supplies by the Belarussian side of BelAZ mining dump trucks, a project for the production of new generation medical atraumatic needles and suture material in Syria, together with LLC Polimedteh, RSPC Cardi- ology and BelMAPO and in the agro-industrial complex.
Plaguicidas en alimentos: riesgo a la salud y marco regulatorio en Veracruz, México
Authors: Díaz-Vallejo Jahaziel , Barraza-Villarreal Albino , Yañez-Estrada Leticia , Hernández-Cadena Leticia
Published: July 2021

Objetivo. Evaluar el cumplimiento de los límites máximos permisibles de residuos de plaguicidas en alimentos del estado de Veracruz, así como evaluar el riesgo para la salud humana debido a su consumo. Material y métodos. Se midieron las concentraciones de residuos de plaguicidas en productos vegetales y se compararon con los valores esta­blecidos como límites de seguridad en el marco regulatorio del uso de plaguicidas. Se calculó el cociente de peligro y sus posibles efectos a la salud. Resultados. El 14.8% de las muestras excedieron la concentración permitida. Se detec­taron plaguicidas prohibidos (metamidofos, monocrotofos, triazofos y clorpirifos) que superaron las dosis de referencia establecidas, lo que pone en riesgo de sufrir posibles efectos a la salud del tipo neurológico, hepatotóxico y alteraciones endocrinas a la población. Conclusiones. Se encontraron residuos de plaguicidas altamente peligrosos en los alimentos, los cuales están prohibidos por los convenios internacionales ambientales derivado de su potencial para causar efectos a la salud y al medio ambiente, por lo cual es necesario su elimi­nación. El marco regulatorio de México debe actualizarse y ser dinámico conforme se avance en el conocimiento de los efectos adversos de los plaguicidas en la salud.
Impacto del aislamiento por la pandemia de Covid-19 en hábitos de la vida diaria en población mexicana
Authors: Aguilar-Díaz Fátima del Carmen , Ramírez-Trujillo María de los Ángeles , Villanueva-Vilchis María del Carmen , De la Fuente-Hernández Javier
Published: July 2021

No disponible.
Removal of Cr(III) From Water By Polyurethane Foam Incorporated With Green Liquor Dregs Waste
Authors: Schoeler Guilherme Pereira , Afonso Thays França , Delucis Rafael de Avila , Okeke Benedict C , Andreazza Robson
Published: July 2021

Water bodies contaminated by heavy metals cause a series of severe environmental and health issues. Chromium compounds stand out as one of the main contaminants since they are widely used by several industries. The low efficiency of effluent treatment facilities and the expensive sanitation procedures needed to remove metals from the water lead to serious concerns about the water quality in Brazil. In this study, a rigid polyurethane foam incorporated with green liquor dregs waste was prepared by the free expansion method. The foam composite and its isolated phases were evaluated for removing Cr(III) from water. The isolated dregs removed 81.93% of the Cr(III), which yielded a removal capacity of 135.45 mg·g-1. Whereas, the foam composite displayed Cr(III) removal percentage and capacity of 36.15% and 58.50 mg·g-1, respectively. Results suggests that the hybrid material may be considered for selective removal and extraction of Cr(III) from contaminated water.
Cobb Angle Measurement Method of Scoliosis Based on U-net Network
Authors: Cui Jia-Li , Gao De-Dong , Shen Sheng-Jun , Wang Lin-Ze , Zhao Yan
Published: July 2021

The Cobb angle is an important indicator for judging the severity of scoliosis. However, the segmentation and corner marking methods based on deep learning have problems such as target area segmentation and corner detection blur in the X-ray Cobb angle measurement. In this paper, a new convex hull algorithm to detect the corners and a mask generation strategy are proposed to improve the accuracy of Cobb angle recognition. On this basis, the Cobb angle measurement method is presented to identify and segment the target area based on U-net network, and then combine the new convex hull algorithm to detect corners and mask generation strategies. A total of 68 corner points were marked on 17 vertebrae, and the corner points detected by the markers were used to calculate the Cobb angle. The experimental results have proved that the U-net based measurement method could effectively improve the corner detection accuracy on the basis of segmentation, thereby reducing the calculation error of the Cobb angle. The Cobb mean absolute error (AMAE) is 9.2832°, and the symmetric mean absolute percentage error (SMAPE) is 21.675%, which achieved a relatively good result compared with the measurement by professional orthopaedist in error.
Separable Convolutional Neural Networks For Facial Expressions Recognition
Authors: Chowanda Andry
Published: July 2021

Social interactions are important for us, human, as social creatures. Emotions play an important part in social interactions. They usually express meanings along with the spoken utterances to the interlocutors. Automatic facial expressions recognition is one technique to automatically capture, recognise, and understand emotions from the interlocutor. Many techniques proposed to increase the accuracy of emotions recognition from facial cues. Architecture such as convolutional neural networks demonstrates promising results for emotions recognition. However, most of the current models of convolutional neural networks require an enormous computational power to train and process emotional recognition. This research aims to build compact networks with depthwise separable layers while also maintaining performance. Three datasets and three other similar architectures were used to be compared to the proposed architecture. The results show that the proposed architecture performed the best among the other architectures. It achieved up to 13% better accuracy and 6-71% smaller and more compact than the other architectures. The best testing accuracy achieved by the architecture was 99.4%.
Regulation of Angiogenesis in Psoriasis by Dermal Mscs-Derived-EDIL3 via the Integrin Pathway
Authors: Niu Xuping , Han Qixin , Li Xinhua , Li Xiaofang , Li Juan , Liu Yanmin , Li Yan , Wu Yan , Zhang Kaiming
Published: July 2021

One of the earliest events in the development of psoriatic lesion is a vascular network expansion. The abnormal vascular network is associated with increased endothelial cells (ECs) survival, proliferation, adhesion, migration, angiogenesis and permeability in psoriatic lesion. Recently, researchers found that the dermal mesenchymal stem cells (DMSCs) in psoriatic lesion involved in course of psoriasis. Our prior study demonstrated the mRNA and protein expression of the epidermal growth factor (EGF)-like repeats and discoidin I-like domains 3 (EDIL3) which is an important angiogenic and anti-inflammatory mediator in DMSCs was significantly upregulated in psoriasis. So, this study aimed to explore the association between DMSCs-derived-EDIL3 and psoriasis-associated angiogenesis in vivo and in vitro. In the present study, we confirmed that in vitro DMSCs-derived-EDIL3 involved in the adhesion, migration and tube formation of ECs via integrin-FAK/MEK/ERK signaling. In vivo, this research found that after injected recombination EDIL3 protein, the epidermis thickness and microvessel density were both elevated in the IMQ-induced psoriasis-like mouse model. Based on these results, we suggested that the modification of DMSCs, EDIL3 and integrin signal pathway might be a novel therapeutic strategy for psoriasis.
Effects of Exenatide on Urinary Albumin in Overweight/Obese Patients with T2DM: A Randomized Clinical Trial
Authors: Kang Chao , Qiao Qiao , Tong Qiang , Bai Qian , Huang Chen , Fan Rong , Wang Hui , Kaliannan Kanakaraju , Wang Jian , Xu Jing
Published: July 2021

In this study, we investigated the effect of exenatide (EXE), a glucagon-like peptide (GLP)-1 receptor agonist, on kidney function, obesity indices, and glucose control in overweight/obese patients with type 2 diabetes mellitus (T2DM). A total of 159 overweight/obese patients with T2DM were randomized to the EXE group or insulin glargine (GLAR) control group for a total treatment period of 24 weeks. EXE intervention significantly reduced the UAC at both week 12 and week 24 endpoints. The levels of the anthropometric parameters and glucose parameters, lipid parameters (TG and HDL-c), and inflammation biomarkers (CRP and TNF-α) in the EXE group were improved at 12 weeks or 24 weeks respectively (P < 0.05). Meanwhile, a comparison between two groups showed significant (P < 0.05) changes in anthropometric parameters, glucose parameters (FBG HBA1C, C-peptide, and HOMA-IR), lipid parameters (TG and HDL-c) and serum levels of CRP, IL-6 and TNF-α. Correlation network analysis showed that FGF 21 had a more central role in improving metabolism in the EXE group, and the change of FGF 21 was significantly negatively correlated with UAC at week 12 and week 24 respectively (r=-0.297, P = 0.010; r=-0.294, P = 0.012). Our results showed that EXE could help patients improve UAC, glycemic levels, and inflammatory biomarkers after a follow-up period of 24 weeks intervention, which may be partly mediating by FGF 21, indicating that EXE is an effective and safe way for albuminuria control in overweight/obese patients with T2DM.
Recent invasion and eradication of two members of the Euwallacea fornicatus species complex (Coleoptera: Curculionidae: Scolytinae) from tropical greenhouses in Europe
Authors: Schuler Hannes , Witkowski Radosław , de Vossenberg Bart van , Hoppe Björn , Mittelbach Moritz , Bukovinszki Tibor , Schwembacher Stefan , de Meulengraaf Bas van , Lange Uwe , Rode Sabine , Andriolo Alessandro , Belka Marta , Mazur Andrzej , Battisti Andrea
Published: July 2021

Ambrosia beetles of the Euwallacea fornicatus species complex are emerging tree pests with a broad host range including important agricultural crops. Native to Southeast Asia, these species were introduced into various countries, where they cause considerable damage to many tree species. Here we report several outbreaks of E. fornicatus s.l. in Europe. The first individuals were found in 2017 in a palm house of a botanical garden in Poznan (Poland) whereas in 2020 an outbreak was detected in a tropical greenhouse in Merano (Italy). In 2021, two additional outbreaks were detected in two greenhouses in Germany, in Erfurt and Berlin. For the latter cases it was possible to trace back the invasion to a distributor of exotic plants in the Netherlands where several infected plants were detected. Molecular analysis show that individuals from Poland and Italy are genetically identical but belong to a different mitochondrial clade than individuals in Germany which are identical to most individuals of two greenhouses in the Netherlands. Moreover, in the two greenhouses in the Netherlands we found beetles that belong to another haplotype of E. fornicatus and two haplotypes of E. perbrevis, a species in the E. fornicatus complex, which has not been previously intercepted in Europe. Our study provides novel insights into the invasion history of E. fornicatus and the first eradication measures in Europe. Considering the high potential of introduction and establishment of Euwallacea ambrosia beetles, particular attention should be paid to monitor the presence of these pests in greenhouses across Europe.
Anionic Methyl Orange Removal from Aqueous Solutions by Activated Carbon Reinforced Conducting Polyaniline as Adsorbent: Synthesis, Characterization, Adsorption Behavior, Regeneration and Kinetics Study
Authors: Bekhoukh Amina , Moulefera Imane , Zeggai Fatima Zohra , Benyoucef Abdelghani , Bachari Khaldoune
Published: July 2021

This work investigated the elimination of Methyl Orange (MO) using a new adsorbent prepared from Activated Carbon (AC) with polyaniline reinforced by a simple oxidation chemical method. The prepared materials were characterized using XRD, TGA, FTIR and nitrogen adsorption isotherms. Furthermore, PANI@CA highest specific surface area values (near 332 m2.g− 1) and total mesoporous volume (near 0.038 cm3.g− 1) displayed the better MO removal capacity (192.52 mg.g− 1 at 298 K and pH 6.0), which is outstandingly higher than that of PANI (46.82 mg.g− 1). Besides, the process's adsorption, kinetics, and isothermal analysis were examined using various variables such as pH, MO concentration and contact time. To pretend the adsorption kinetics, various kinetics models, the pseudo first- and pseudo second- orders, were exercised to the experimental results. The kinetic analysis revealed that the pseudo second order rate law performed better than the pseudo first order rate law in promoting the formation of the chemisorption phase. In the case of isothermal studies, an analysis of measured correlation coefficient (R2) values showed that the Langmuir model was a better match to experimental results than the Freundlich model. By regeneration experiments after five cycles, acceptable results were observed.
Linear programming feedrate optimization - Adaptive path sampling and feedrate override
Authors: Petráček Petr , Vlk Bořivoj , Švéda Jiří
Published: July 2021

This paper focuses on two aspects of feedrate optimization via linear programming methods. Namely, the effect of curve sampling on time optimality of the resultant feedrate profile and a method of feedrate profile adaptation in response to a feedrate override command. A comparison of three distinct curve sampling approaches (uniform in parameter, uniform in arc length and curvature adaptive) is performed on a series of standard tool path curves. Results show that the curvature-adaptive sampling approach leads to substantial machining time reduction for tool path curves displaying high degree of curvature variation. Secondly, a method by which a new feedrate profile can be calculated in response to a feedrate override command is developed. The method formulates a new set of boundary conditions on the control point sequence of the feedrate curve in such a way that the resulting profile is guaranteed to coincide with the currently active profile up to the moment of override command, while minimizing the arc length necessary for transition to the newly commanded feedrate.
Determination of Some Growth Characteristics and Some Blood Values of The Goat Kids Fed with the Feed Containing Whey and Propolis
Authors: MANAV Selda , YILMAZ Murat
Published: July 2021

In this study, it was aimed to obtain an alternative, more economical and preferable milk substitute feed by adding whey powder to cow's milk in kid rearing and to determine the effect of propolis supplement on this diet. 40 Saanen goat kids born in the same period were divided into 4 groups, on average 7 days after taking colostrum, and while the 10 kids in the control group were kept together with their mothers. the kids in the other three groups, 10 heads in each one, were taken into seperate sections. Kids in all three experimental groups were fed only formula. In addition to the feed, 0.4 cc and 0.2 cc propolis were given to the kids in the second and third experimental groups, respectively, once a day. Some growth and development parameters and rectal temperature were measured once a week for 5 weeks from all groups and morning and evening diarrhea scoring was done. Some biochemical and hematological analyzes were performed. According to all the results obtained, the differences between the groups were found to be significant in terms of body temperature, glucose and urea evaluations, and the differences within the group in other characteristics were statistically significant (P < 0.05). The insignificant difference between the average growth and development parameters of the kids in the groups fed with the formula and the average of the kids in the control group is an important result in terms of growing kids economically and bringing goat's milk to the economy. According to the diarrhea scores, it has been observed that propolis is effective on diarrhea and can be used in growing kids as a preventive measure. Feeding kids with the formula was found more economical than feeding their mother's milk. As a result of this study, it can be said that the use of milk replacers containing whey and propolis will positively affect the growth, development and health of the kid.
Characterization of Aluminium Hybrid Metal Matrix Composites
Authors: Srivast Siddharth , Malik Vansh , Bhatnagar Mudit K. , Verma Neeraj , G Mamatha T , VISHNOI MOHIT
Published: July 2021

Hybrid Metal Matrix composites have emerged as an epicentre of material research due to their vast applications and a wide array of reinforcement combinations. In this experiment, a hybrid Aluminum metal matrix composite has been fabricated by the double (two steps) stir casting method. The present study evaluates the mechanical properties of AA6061 in varying concentrations of silicon carbide with 5, 10, 15 and 20 weight percent (wt.%), in addition to Rice Husk Ash, Tungsten Carbide and Alumina Powder which are in a fixed quantity. Mechanical properties have been evaluated by conducting an Impact test, Hardness test, Flexural test and Tensile Strength. In addition, micrograph Images have been incorporated for analysing the microstructural characteristics of the Hybrid AMMC. It was observed that MMC properties such as Tensile Strength, Yield Strength, Hardness, Impact Strength were highest at 20 wt.% SiC. Hence, it was inferred that 20wt% SiC was an appropriate concentration for applications in automobile and aerospace pertaining to its augmented mechanical properties. In conclusion, prospects of future research are also explored.