bluuebunny/crossref_metadata_2025 huggingface dataset:
Positive solutions for the Robin p-Laplacian problem with competing nonlinearities
Authors: Gasiński Leszek , Papageorgiou Nikolaos S.
Published: January 2019

We consider a parametric nonlinear elliptic equation driven by the Robin p-Laplacian.
The reaction term is a Carathéodory function which exhibits competing nonlinearities
(concave and convex terms). We prove two bifurcation-type results describing the set of
positive solutions as the parameter varies.
In the process we also prove two strong comparison principles for Robin equations.
These results are proved for differential operators which are more general than the
p-Laplacian and need not be homogeneous.
Emodin promotes apoptosis of human endometrial cancer through regulating the MAPK and PI3K/ AKT pathways
Authors: Jiang Jun , Zhou Nanyang , Ying Pian , Zhang Ting , Liang Ruojia , Jiang Xuelu
Published: January 2019

Emodin, a major component of rhubarb, has anti-tumor effects in a variety of cancers, influencing multiple steps of tumor development through modulating several signaling pathways. The aim of this study is to examine the effect of emodin on cell apoptosis and explore the underlying mechanisms in human endometrial cancer cells. Here we report that emodin can inhibit KLE cell proliferation and induce apoptosis in a time- and dose-dependent manner. Western blot assay found that emodin was involved in MAPK and PI3K/Akt signaling pathways. Specifically, emodin significantly suppressed the phosphorylation of AKT, and enhanced the phosphorylation of MAPK pathways. Furthermore, the generation of reactive oxygen species (ROS) was up-regulated in KLE cells upon treatment with emodin, while the anti-oxidant agent N-acetyl cysteine (NAC) can inhibit emodin-induced apoptosis and promote the activation of AKT and Bcl-2. Taken together, we revealed that emodin may induce apoptosis in KLE cells through regulating the PI3K/AKT and MAPK signaling pathways, indicating the importance of emodin as an anti-tumor agent.
’National Belonging’ in Legal and Diplomatic Formulas: The Pole’s Card as a Legacy of Poland’s Colonial History
Authors: Ładykowski Paweł
Published: January 2019

The article explores the sources of the idea of nation as it is encoded in the legislative framework of the Pole’s Card and its implications for the processes of identity-making taking place beyond the eastern borders of the Polish state. Given the problems with defining the role of the historical Polish diaspora in the East, the question of the conceptualization of national belonging is significant and has practical consequences at the macro-, meso- and micro-levels. The argument of the paper is twofold: (1) On the one hand, the document of the Pole’s Card reflects a specific inclusive—”cultural”— conception of the nation. In this conception, which is forged by the Polish policymakers, the conditions whereby the national belonging can be achieved are widely conceived. (2) On the other hand, the administrative decision-making process and the diplomatic practice of granting the Card prioritizes and executes the exclusive conception of the nation with its limited ethnic, religious (Roman Catholic) and linguistic background. This way, the document of the Pole’s Card becomes a legal device for establishing new social distinctions in societies of Poland’s eastern neighbours. By discussing this case on the ground, this paper hopes to demonstrate the ways in which the new creative notions of the nationhood are forged in Poland.
Isotopic Abundances and Atomic Weights: History of IUPAC Commission II.1 in the ­Service of Chemistry
Authors: Laeter John R. De
Published: January 2019

Atomic weights are of fundamental importance in science, technology, trade and commerce. In particular, atomic weights relate mass to molar quantities. It is therefore not surprising that the measurement of atomic weights has played a central role in the development of chemistry and continues to be a key component in the progress of discipline.
Isotopes Matter
Authors: Holden Norman E. , Coplen Tyler B. , Mahaffy Peter
Published: January 2019

Two years ago, the King’s Centre for Visualization in Science (KCVS) at The King’s University, Edmonton released a new digital interactive version of the IUPAC Periodic Table of the Elements and Isotopes with accompanying educational resources at an International Conference on Chemistry Education. It can be found at www.isotopesmatter.com. The effort was part of an IUPAC project [1]. The science behind this new table was developed by Inorganic Chemistry Division scientists working for over a decade on an earlier IUPAC project [2]. These projects were joint efforts between the IUPAC Committee on Chemistry Education (CCE) and the Inorganic Chemistry Division.
Application of 2N Design of Experiment Method for The Evaluation of The Efficiency and Cross-Effects of Oilfield Chemicals
Authors: Lukács Zoltán , Kristóf Tamás
Published: January 2019

It has been known for a long time that oilfield chemicals used for different purposes (corrosion and scale inhibitors, scavengers, biocides, etc.) can modify the efficiency of each other. These cross-effects can exhibit adverse or beneficial impacts and may modify the overall corrosiveness of the medium to a great extent. However, there is no standard procedure in order to evaluate the cross-effects, i.e. the extent to which the effect of one of the chemicals is modified by the addition of another. The 2N Design of Experiment (DoE) method provides a robust and simple statistical way to evaluate the change in efficiency of oilfield chemicals owing to the addition of other additives. The 2N DoE method can also be applied to other systems. In the present work the effects and cross-effects in systems consisting of a corrosion inhibitor, as well as an oxygen and a hydrogen sulphide scavenger are investigated and successfully demonstrated in a typical oilfield corrosion system with electrochemical corrosion monitoring methods.
Worker Movement Diagram Based Stochastic Model of Open Paced Conveyors
Authors: Ruppert Tamás , Abonyi János
Published: January 2019

Human resources are still utilized in many manufacturing systems, so the development of these processes should also focus on the performance of the operators. The optimization of production systems requires accurate and reliable models. Due to the complexity and uncertainty of the human behavior, the modeling of the operators is a challenging task. Our goal is to develop a worker movement diagram based model that considers the stochastic nature of paced open conveyors. The problem is challenging as the simulator has to handle the open nature of the workstations, which means that the operators can work ahead or try to work off their backlog, and due to the increased flexibility of the moving patterns the possible crossings which could lead to the stopping of the conveyor should also be modeled. The risk of such micro-stoppings is calculated by Monte-Carlo simulation. The applicability of the simulator is demonstrated by a well-documented benchmark problem of a wire-harness production process.
Effect of Algae Treatment On Stevia Rebaudiana Growth
Authors: Czinkóczky Réka , Németh Áron
Published: January 2019

Stevia rebaudiana Bertoni is a small, perennial and herbaceous shrub which originated in Paraguay (South America). Stevia rebaudiana is not native to Hungary but its cultivation and consumption may have many benefits, e.g. to reduce blood pressure and as a non-caloric sweetener. Steviol glycosides, mostly stevioside and rebaudioside A, located in the leaves are about 200–300 times sweeter than sucrose. S. rebaudina cultivation in Hungary would offer many opportunities in healthcare and the sweet industry. With the aim of achieving good green biomass yields, the effect of MACC4 autotrophic and heterotrophic algae strains was investigated by testing them as both leaf and soil fertilizers in the soil of Stevia rebaudiana seedlings and in its aqueous rooting experiments. In one of the later set up, the formation of roots was improved by combining the application of red light and algae treatment.
Regularity of fuzzy convergence spaces
Authors: Li Lingqiang , Jin Qiu , Yao Bingxue
Published: January 2019

(Fuzzy) convergence spaces are extensions of (fuzzy) topological spaces. ⊤-convergence spaces are one of important fuzzy convergence spaces. In this paper, we present an extending dual Fischer diagonal condition, and making use of this we discuss a regularity of ⊤-convergence spaces.
Sources of lead exposure in various countries
Authors: Obeng-Gyasi Emmanuel
Published: January 2019

This review evaluates the sources of lead exposure worldwide. Studies from searches relating to sources of lead exposure in various countries within different regional zones were reviewed. Results indicated that in Nigeria, exposure sources include electronic waste, paint and batteries. In Mexico exposure sources include glazed ceramics, lead contaminated utensils and lead contaminated water, for India lead sources include cosmetics and traditional medicines. Sources of lead exposure in China include e-waste, traditional medicines and industrial emissions. In France, exposure sources included lead paint from older homes, imported ceramics and cosmetics and industrial emissions. Australia’s exposure sources include paint, dust, imported toys and traditional medicines. Finally, in the United States exposure sources included paint, the industrial legacy of lead exposure and batteries. In high-income countries (HICs) the legacy of lead exposure keeps populations continuously exposed. In lower- and middle-income countries (LMICs), in addition to the legacy of lead exposure, lack of regulations or the inability to enforce regulations keeps populations exposed. In all, evidence suggests that lead exposure remains an issue of public health significance in both HIC and LMIC.
Experimental Study on Influence of Material Parameters on Bond Behavior of Glued-in Rod Connection
Authors: Wang Fangbo , Xiong Haibei
Published: January 2019

Glued-in rod connection for timber structure has shown great potential for engineering applications because of its high strength, stiffness, and aesthetic appeal. During the past few decades, extensive research has been carried out to investigate the effects of geometrical parameters on bonding behavior of glued-in rod connection. On the other hand, comprehensive studies on the effects of material parameters are rare. This article presents an experiment program to study the effects of a number of material parameters—adhesive type, rod surface type, glued-in direction—of glued-in rod connection. Twenty-four glued-in rod specimens were tested using a universal testing machine, and the full bond-slip behaviors of specimens were collected. Test result shows that bond strength of glued-in rod connection with epoxy resin is 20 % to 30 % higher than that with polyurethane, and the effect of rod types on bond strength is negligible. Although parallel-to-grain glued-in rod connection has higher bond strength than that of perpendicular-to-grain connection, sudden brittle failure is observed for parallel-to-grain glued-in rod connection. Furthermore, a new bonding strength model is proposed to account for the effects of material parameters.
DIC Measurement on Stress Wave Propagation and Strain Field Distribution Induced by Deep Rock Blasting
Authors: Yang Liyun , Wang Qingcheng , Ding Chenxi , Zhang Lanyue
Published: January 2019

An ultra-high-speed digital image correlation system was applied in a blasting experiment that simulates the blasting response of deep rock under high ground stress. The full field strain evolutionary process of the specimen and the strain time histories of certain gauges were analyzed. Under a static stress field (simulating high ground stress), stress concentration occurs within three times the radius of the blasthole, and then, according to the region of stress concentration, the specimen plane was divided into near zone and far zone of the blasthole. There was no significant difference between deep and superficial formation in the law of explosive stress wave propagation in the blasthole far zone, which was based on the blasting compression zone, crack zone, and vibration zone, and elastic mechanics theory. Through nonlinear fitting, the explosive stress wave attenuation function between the maximum principal strain and the distance from the blasthole was obtained quantitatively, namely, by εmax=697+718·e−0.166·s. In addition, the strain value of the blasthole far zone caused by the combined action of the blasting stress field and the static stress field was equal to the linear superposition of the strain values caused by these two fields separately.
Escolas de fronteira: educação integral e currículo fronteiriço intercultural
Authors: Borges Paulo Ricardo , Fernández Ana Lourdes
Published: January 2019

A extensão é um instrumento importantíssimo para as universidades institucionalizarem suas relações com a sociedade local e regional. Um dos projetos desenvolvidos pelo Centro de Letras e Comunicação (CLC) da Universidade Federal de Pelotas (UFPel) denomina-se “Programa Escolas Interculturais de Fronteira - PEIF. As atividades do PEIF estão presentes em diferentes projetos extensionistas que, desde 2013, desenvolvem importantes ações nas áreas de educação intercultural em zonas de fronteira e de formação continuada de docentes das escolas das redes públicas municipal e estadual de ensino. As ações extensionistas são desenvolvidas nas cidades gêmeas de Santana do Livramento/Rivera, em parceria com a Secretaria Municipal de Educação e a 19ª Coordenadoria Estadual de Educação, com apoio do Ministério da Educação e da Secretaria de Educação Básica – MEC/SEB. A continuidade e o aprofundamento das ações extensionistas com parceiros das escolas públicas do Brasil e do Uruguai tornam-se importantes para que as atividades propostas em conjunto com os professores e as escolas do Brasil e do Uruguai sejam plenamente executadas e os resultados sejam devidamente avaliados conjuntamente, com o objetivo de aprimorar as relações institucionais e as atividades educacionais desenvolvidas naquela zona de fronteira. Já foram desenvolvidos, sob orientação da UFPel/CLC, doze projetos de extensão relacionados ao PEIF nas seguintes áreas: formação continuada, língua, cultura, história, interculturalidade, vigem intercultural, diversidade cultural, metodologia de ensino e projetos de pesquisa.
Cenpj Regulates Cilia Disassembly and Neurogenesis in the Developing Mouse Cortex
Authors: Ding Wenyu , Wu Qian , Sun Le , Pan Na Clara , Wang Xiaoqun
Published: January 2019

Primary cilia are microtubule-based protuberances that project from the eukaryotic cell body to sense the extracellular environment. Ciliogenesis is closely correlated to the cell cycle and defects of cilia are related to human systemic diseases such as primary ciliary dyskinesia. However, the role of ciliogenesis in cortical development remains unclear. Here, we demonstrate that Cenpj, a protein that is required for centriole biogenesis, plays a role in regulating cilium disassemblyin vivo. Depletion of Cenpj in neural progenitor cells results in long cilia and abnormal cilia disassembly. Radial glial cells Cenpj depletion exhibit uncompleted cell division, reduced cell proliferation, and increased cell apoptosis in the developing mouse cerebrum cortex, leading to microcephaly. In addition, Cenpj depletion causes long and thin primary cilia and motile cilia in adult neural stem cells and reduced cell proliferation in the subventricular zone. Furthermore, we show that Cenpj regulates cilia disassembly and neurogenesis through Kif2a, a plus-end-directed motor protein. These data collected from mice of both sexes provide insights into how ciliogenesis plays roles in cortical development and how primary microcephaly is induced byCenpjmutations in humans.

SIGNIFICANCE STATEMENTAutosomal recessive primary microcephaly is a neurodevelopmental disorder with the major symptoms of reduction of circumference of the head, brain volume, and cortex thickness with normal brain architecture in birth. We used conditional Cenpj deletion mice and found that neural progenitor cells (NPCs) exhibited long primary cilia and abnormal cilium appendages. The defective cilium disassembly caused by Cenpj depletion might correlate to reduced cell proliferation, uncompleted cell division, cell apoptosis, and microcephaly in mice. Cenpj also regulates the cilium structure of adult neural stem cells and adult neurogenesis in mice. Additionally, our results illustrate that Cenpj regulates cilia disassembly and neurogenesis through Kif2a, indicating that primary cilia dynamics play a crucial role in NPC mitosis and adult neurogenesis.
The Beavis Effect in Next-Generation Mapping Panels inDrosophila melanogaster
Authors: King Elizabeth G , Long Anthony D
Published: January 2019

A major goal in the analysis of complex traits is to partition the observed genetic variation in a trait into components due to individual loci and perhaps variants within those loci. However, in both QTL mapping and genetic association studies, the estimated percent variation attributable to a QTL is upwardly biased conditional on it being discovered. This bias was first described in two-way QTL mapping experiments by William Beavis, and has been referred to extensively as “the Beavis effect.” The Beavis effect is likely to occur in multiparent population (MPP) panels as well as collections of sequenced lines used for genome-wide association studies (GWAS). However, the strength of the Beavis effect is unknown—and often implicitly assumed to be negligible—when “hits” are obtained from an association panel consisting of hundreds of inbred lines tested across millions of SNPs, or in multiparent mapping populations where mapping involves fitting a complex statistical model with several d.f. at thousands of genetic intervals. To estimate the size of the effect in more complex panels, we performed simulations of both biallelic and multiallelic QTL in two major Drosophila melanogaster mapping panels, the GWAS-based Drosophila Genetic Reference Panel (DGRP), and the MPP the Drosophila Synthetic Population Resource (DSPR). Our results show that overestimation is determined most strongly by sample size and is only minimally impacted by the mapping design. When < 100, 200, 500, and 1000 lines are employed, the variance attributable to hits is inflated by factors of 6, 3, 1.5, and 1.1, respectively, for a QTL that truly contributes 5% to the variation in the trait. This overestimation indicates that QTL could be difficult to validate in follow-up replication experiments where additional individuals are examined. Further, QTL could be difficult to cross-validate between the two Drosophila resources. We provide guidelines for: (1) the sample sizes necessary to accurately estimate the percent variance to an identified QTL, (2) the conditions under which one is likely to replicate a mapped QTL in a second study using the same mapping population, and (3) the conditions under which a QTL mapped in one mapping panel is likely to replicate in the other (DGRP and DSPR).
Deleterious Mutation Burden and Its Association with Complex Traits in Sorghum (Sorghum bicolor)
Authors: Valluru Ravi , Gazave Elodie E , Fernandes Samuel B , Ferguson John N , Lozano Roberto , Hirannaiah Pradeep , Zuo Tao , Brown Patrick J , Leakey Andrew D B , Gore Michael A , Buckler Edward S , Bandillo Nonoy
Published: January 2019

Sorghum (Sorghum bicolor (L.) Moench) is a major staple food cereal for millions of people worldwide. Valluru et al. identify putative deleterious mutations among ∼5.5M segregating variants of 229 diverse sorghum...

Sorghum (Sorghum bicolor L.) is a major food cereal for millions of people worldwide. The sorghum genome, like other species, accumulates deleterious mutations, likely impacting its fitness. The lack of recombination, drift, and the coupling with favorable loci impede the removal of deleterious mutations from the genome by selection. To study how deleterious variants impact phenotypes, we identified putative deleterious mutations among ∼5.5 M segregating variants of 229 diverse biomass sorghum lines. We provide the whole-genome estimate of the deleterious burden in sorghum, showing that ∼33% of nonsynonymous substitutions are putatively deleterious. The pattern of mutation burden varies appreciably among racial groups. Across racial groups, the mutation burden correlated negatively with biomass, plant height, specific leaf area (SLA), and tissue starch content (TSC), suggesting that deleterious burden decreases trait fitness. Putatively deleterious variants explain roughly one-half of the genetic variance. However, there is only moderate improvement in total heritable variance explained for biomass (7.6%) and plant height (average of 3.1% across all stages). There is no advantage in total heritable variance for SLA and TSC. The contribution of putatively deleterious variants to phenotypic diversity therefore appears to be dependent on the genetic architecture of traits. Overall, these results suggest that incorporating putatively deleterious variants into genomic models slightly improves prediction accuracy because of extensive linkage. Knowledge of deleterious variants could be leveraged for sorghum breeding through either genome editing and/or conventional breeding that focuses on the selection of progeny with fewer deleterious alleles.
La Amazonía y el Petén: ¿dos lugares improbables para el desarrollo de las civilizaciones?
Authors: Solórzano Fonseca Juan Carlos
Published: January 2019

Durante casi todo el siglo XX los investigadores dieron por sentado que la región del Amazonas en Brasil, el Petén en Guatemala, Belice y sur de Yucatán eran territorios cuyo tipo de suelos, vegetación y clima no eran aptos para sustentar una agricultura productiva, sostenible a largo plazo y capaz de sustentar grandes concentraciones de población, ni sociedades complejas en la época precolombina. No fue sino hasta finales de la centuria pasada que gracias a las investigaciones arqueológicas y etnohistóricas de las últimas décadas se modificó tal visión. La información reciente viene a probar que tanto en la Amazonía como el Petén sus pobladores fueron capaces de implementar técnicas de producción agrícola adaptadas a la ecología de la región, capaces de generar excedentes suficientes para un gran crecimiento poblacional. Esto posibilitaría la aparición de sociedades no solo de gran densidad demográfica sino también de gran complejidad social.
Recuperar el legado histórico y etnográfico de Henri Pittier
Authors: Cruz Meléndez Carlos
Published: January 2019

Henri Pittier es un científico de origen suizo, quien realiza una extensa como dilatada investigación en la Costa Rica de finales del siglo XIX e inicios del siglo XX en campos como la botánica y la geografía. Pero también incursiona en áreas de la lingüística, la etnografía y la historia. En este ensayo se busca mostrar la importancia que, en particular para las ciencias sociales, tiene la recuperación y estudio de este legado. Para este propósito y a manera de ejemplos, se comenta la actualidad y pertinencia de tres ensayos o informes del investigador donde se abordan temas como la longevidad de los habitantes de la región nicoyana, las costumbres de los pueblos indígenas y su relación con el Estado, o el proceso de expansión de la sociedad nacional costarricense hacia la actualmente denominada “Zona Sur”.
Entrevista con Rafael Cuevas Molina: Estados-nación, identidades e integración en América Latina
Authors: Cuevas Molina Rafael
Published: January 2019

Los Estados-nación se encuentran en un momento de cuestionamiento de su vigencia por los procesos de globalización y seguramente hacia el futuro, tendencialmente, esta situación se irá acentuando. Digo tendencialmente porque es posible que haya momentos en los que tal situación se revierta momentáneamente, pero a largo plazo, seguramente darán paso a nuevas formas de organización macrosocial.
Las estrategias educativas para la formación ciudadana según su alcance y sentido
Authors: González Rivero Berta Margarita
Published: January 2019

En el artículo se presentan las ideas fundamentales acerca de la formación ciudadana. A partir de la conceptualización diferente de esta, se determina una clasificación de las estrategias educativas para lograrla en estudiantes universitarios. Loa grupos de estrategias están creados por el alcance y sentido que tienen las acciones de influencia sobre ese estudiante. Se aportan experiencias de diferentes autores según la clasificación creada.
La marca país Esencial Costa Rica: más allá del bienestar ambiental
Authors: Arce Aguirre Dalia
Published: January 2019

El presente trabajo da un panorama sobre lo que es la marca país Esencial Costa Rica. Al ser un sello mundial, se analizan los discursos en torno a su promoción tomando en cuenta que este sello es un atractivo para la apertura económica y para la vinculación con inversores o empresas extranjeras. En el caso costarricense, se puede observar que lo ambiental está acompañado con lo político y económico.
Community-Academic Peer Review: Prospects for Strengthening Community-Campus Engagement and Enriching Scholarship
Authors: Levkoe Charles Z. , Schembri Victoria , Wilson Amanda DiVito
Published: January 2019

Scholarly peer review is hailed as an indispensable process to maintain quality and rigour in research publications. However, there is growing recognition of the limitations of peer review and concerns about the unexamined assumptions surrounding the processes that favour academic ways of knowing. In this paper, we build on these debates by exploring the possibilities for engaging communities in shaping and assessing the value of knowledge. Drawing on insights of a community-academic peer review pilot project through a pan-Canadian research partnership, we reflect on the value of incorporating community perspectives into research review processes and challenges of scaling-up these efforts. We argue that the perspectives of community-based practitioners are a necessary part of peer review—especially for Community-Based Research—to increase validity and accountability. This process gives academics and practitioners the power to collectively assess and evaluate knowledge products. Fundamentally, these efforts are about reviving higher education and critical research as part of a democratic public sphere that is open, inclusive, and relevant. We conclude by reflecting on the value of incorporating community perspectives into the peer review process. We also offer recommendations on how to recognize and incorporate community knowledge and experiences into assessment structures.
Perinatal Risk Factors and Outcome Coding in Clinical and Administrative Databases
Authors: Tawfik Daniel S. , Gould Jeffrey B. , Profit Jochen
Published: January 2019

BACKGROUND AND OBJECTIVES:

Administrative databases may allow true population-based studies and quality improvement endeavors, but the accuracy of billing codes for capturing key risk factors and outcomes needs to be assessed. We sought to describe the performance of a statewide administrative database and the clinical database from the California Perinatal Quality Care Collaborative (CPQCC).

METHODS:

This population-based retrospective cohort study linked key perinatal risk factors and outcomes from the 133-unit CPQCC database to relevant billing codes from administrative maternal and newborn inpatient discharge records, for 50 631 infants born from 2006 to 2012. Using the CPQCC record as the gold standard, we calculated the positive predictive value, negative predictive value, and Matthews correlation coefficient for each item, then evaluated comparative performance across units.

RESULTS:

The Matthews correlation coefficient was highest (>0.7; strong positive correlation) for multiple delivery, Cesarean delivery, very low birth weight, maternal hypertension, maternal diabetes, patent ductus arteriosus, in-hospital death, patent ductus arteriosus and retinopathy of prematurity surgeries, extracorporeal life support, and intraventricular hemorrhage. Maternal chorioamnionitis, fetal distress, retinopathy of prematurity staging, chronic lung disease, and pneumothorax were the least reliably coded. Maternal factors and delivery details were more reliably coded in the maternal inpatient record than the newborn inpatient record.

CONCLUSIONS:

Several important perinatal risk factors and outcomes are highly congruent between these administrative and clinical databases. Several subjective risk factors and outcomes are appropriate targets for data improvement initiatives. The ability for timely extraction of administrative inpatient data will be key to their usefulness in quality metrics.
Interacción tangible para la Compensación Social de procesos mediados en niños con diversidad funcional
Authors: Passerino Liliana , Roselló Teresa Coma , Baldassarri Sandra
Published: January 2019

Las tecnologías pueden tener un papel mediador y potenciador del aprendizaje del alumnado con diversidad funcional. En este artículo se discute la compensación social en procesos mediados con tecnologías y se presenta un estudio de caso en el que se utiliza interacción tangible con 6 niños con autismo y 7 con problemas específicos de comunicación en un proceso de intervención educativa. A partir de los datos, se analiza la interacción social y los procesos de mediación emergentes en el grupo de estudio. Los resultados muestran una mejoría de las interacciones en la mayoría de los participantes así como su capacidad de representación de los objetos manipulados, facilitando la transición de lo concreto a lo simbólico. Ese cambio se mostró más evidente en los participantes que no tenían lenguaje oral funcional y alfabetización. Las mediaciones con la interacción tangible y las diferentes formas de representación posibilitaron el acceso al lenguaje simbólico y potenciaron la zona de desarrollo próximo, clave para la compensación social señalada por Vygotsky.
Multiparentalidade e seus efeitos na sucessão
Authors: Mares Flávio Miranda , Paranhos Vinicius Lucas
Published: January 2019

A evolução contínua do direito de família, motivada principalmente pelas chamadas famílias recompostas, e com o objetivo de observar o Princípio do melhor interesse do menor, trouxe consigo a possibilidade de figurar no registro de nascimento de um indivíduo mais de um pai ou mais de uma mãe, sem, no entanto, perderem aqueles anteriormente registrados. Como fundamento principal, tem-se o texto constitucional que prevê a igualdade entre os modelos de família, bem como a sua pluralidade, sendo que, em qualquer caso, todas merecerão o mesmo tratamento e proteção do Estado, tendo em vista o seu caráter formador do indivíduo. No entanto, por se tratar de uma novidade do Direito de Família, não se podem deixar de lado os efeitos que tal instituto traria, principalmente dentro do Direito Sucessório, ao tratar dos bens a serem herdados e por quem seriam herdados.
DISTRIBUSI SPASIAL IKAN FAMILI SCARIDAE DI PERAIRAN TAMAN NASIONAL BUNAKEN, SULAWESI UTARA
Authors: Rachmad Basuki
Published: January 2019

ABSTRAKIkan karang Famili  Scaridae adalah salah satu ikan herbivora yang hidup di ekosistem terumbu karang. Namun keberadaan dan kondisi ikan ini belum banyak diketahui di perairan Taman Nasional Bunaken. Penelitian ini bertujuan untuk mengetahui komposisi dan distribusi ikan famili Scaridae yang berhubungan dengan terumbu karang, di Taman Nasional Bunaken yang dilakukan di tiga pulau pada bulan Februari hingga Mei 2017. Pengamatan ini dilakukan dengan metode sensus visual Line Intercept Transect (LIT) Dalam penelitian ini ditemukan keragaman ikan famili Scaridae terdiri dari 9 spesies, dua spesies ikan yaitu Scarus spirus dan S. niger memiliki distribusi spasial di seluruh perairan. Jenis ikan yang memiliki kelimpahan tertinggi adalah S. gobbhan (110 ind/ha).  Kesamaan spesies dicirikan oleh kecenderungan dari kelompok yang terjadi di perairan Pulau Bunaken yang kerucut. Penilaian ekologi ikan Scaridae menunjukkan bahwa terumbu karang di perairan Taman Nasional Bunaken masih dalam kondisi baik.Kata Kunci: Distribu spasial Scaridae, keanekaragaman, Taman Nasional Bunaken ABSTRACTCoral fishes Scaridae family is one of the herbivorous fishes that live in coral reef ecosystem. But  the existence and condition of this fishes has not been widely known in  of Bunaken National Park waters. This study aims to determine the composition and distribution of Scaridae family associated with coral reefs, in Bunaken National Park conducted at three islands in February to May 2017. The observation is ware made with the visual census method Line Intercept Transect (LIT)  In this study found diversity of Scaridae family consists of 9 species, two species Scarus spirus and S. niger has spatial distribution throughout the waters. S. gobbhan has the highest abundance (110 ind/ha). The similarity of species characterized by the tendency to from groups that occur in the conical Bunaken Island waters. Ecological assessment of the Scaridae fish shows that the coral reefs in the waters of Bunaken National Park are still in good condition.Key Words: Spasial Distributian, Scaridae, diversity, Bunaken National Park
Ya?odhar? in J?takas
Authors: Shaw Sarah
Published: January 2019

This paper discusses the role of the Buddha’s wife, Yasodhar?/R?hulam?t?, in P?li J?takas. Noting her continued popularity in South and Southeast Asian Buddhism, it considers her path to liberation seen as a composite whole, through many lifetimes, and considers some of the literary implications of this multiple depiction. The intention of this paper is to initiate more discussion about this figure as a sympathetic and central presence in Southern Buddhist text and practice.
The Gathering of Intentions: A History of Tibetan Buddhist Tantra, by Jacob P. Dalton
Authors: Van Schaik Sam
Published: January 2019

The Gathering of Intentions: A History of Tibetan Buddhist Tantra, by Jacob P. Dalton. Columbia University Press, 2016. 272pp. Hb. $60.00 (cloth), ISBN-13: 9780231176002.
The Ins and Outs of Collateral Re-Use
Authors: Infante Sebastian , Press Charles , Strauss Jacob
Published: January 2019

In this article, we empirically document how primary dealers use and re-use collateral (that is, financial securities) in the United States.
Avaliação da qualidade da água na Bacia Hidrográfica do Arroio Preto, Santa Cruz do Sul, RS, Brasil
Authors: Wiesel Patrik Gustavo , Dresch Elias , Ramos de Santana Eduardo Rodrigo , Alexis Lobo Eduardo
Published: January 2019

A pesquisa objetivou avaliar a qualidade da água da Bacia Urbana do Arroio Preto, Santa Cruz do Sul, RS, aplicando o Índice de Qualidade da Água (IQA) adaptado para sistemas lóticos sul brasileiros, em três pontos de amostragem ao longo do Arroio, Ponto 1, trecho superior; Ponto 2, trecho intermediário; e Ponto 3 próximo à foz. Foram realizadas 19 campanhas entre 2007 e 2016, medindo: temperatura, pH, turbidez, oxigênio dissolvido, demanda bioquímica de oxigênio, nitrato, nitrito, nitrogênio amoniacal total, fosfato, sólidos totais dissolvidos e coliformes termotolerantes. Os resultados indicaram que houve uma significativa diminuição da qualidade da água (p
Fitoacumulacion de arsénico en plantas terrestres del desierto de Chile
Authors: Schultze Oscar Diaz , Tapia Yasna , Pastene Rubén
Published: January 2019

El objetivo de este trabajo fue mostrar la capacidad de 4 especies de plantas terrestres: Atriplex atacamensis, Atriplex halimus, Lupinus microcarpus y Tessaria absinthioides para acumular arsénico en suelos agrícolas de la Región de Antofagasta, Chile, para ser utilizadas en fitorremediación y/o revegetación para la recuperación de suelos contaminados, así como también mostrar los efectos del arsénico en las especies L. microcarpus, A. halimus y A. atacamensis a través de bioindicadores de estrés. Los resultados indican que A. atacamensis y A. halimus resisten la contaminación por arsénico, acumulando el metaloide principalmente en las raíces, pero no en el caso de L. microcarpus. Síntomas visuales de toxicidad por arsénico, tales como clorosis y necrosis en las hojas, hojas arrugadas y decrecimiento, fueron observados en la especie L. microcarpus.
Gestión del riesgo en poblaciones humanas expuestas a contaminantes químicos ambientales
Authors: Schultze Oscar Diaz , Pastene Rubén
Published: January 2019

El objetivo de la presentación es entregar información actualizada acerca del procedimiento recomendado por agencias internacionales, tales como la Agencia de Estados Unidos para la Protección Ambiental (del inglés USEPA), en los estudios sobre evaluación y la gestión del riesgo en poblaciones humanas expuestas a contaminantes químicos. La evaluación del riesgo para la salud humana, por acción de agentes xenobióticos, incluye las siguientes etapas: Identificación del peligro, evaluación de la exposición, evaluación de la toxicidad, evaluación de los efectos y caracterización del riesgo. Con esta última etapa, se puede llevar a cabo el Plan de Acción, el cual incluye las diferentes medidas que se aplicarán para reducir o mitigar el (los) riesgo(s) y que forma parte de la gestión del riesgo. Se concluye en destacar la importancia de considerar en la evaluación del riesgo, las relaciones dosis-respuesta y tiempo-respuesta, las cuales permiten poder relacionar adecuadamente con las alteraciones epigenéticas observadas.
Histórico do programa de Pagamento por Serviços Ambientais (PSA) na Bacia Hidrográfica do Arroio Andréas, RS, Brasil
Authors: Delevati Dionei Minuzzi , Moraes Jorge Amaral de , Costa Adilson Ben da , Lobo Eduardo Alexis
Published: January 2019

A UNISC, em parceria com a Empresa Universal Leaf Tabacos e Fundación Altadis (organização sem fins lucrativos, pertencente ao Grupo Imperial Tobacco), e contando com o apoio do Município de Vera Cruz, RS, desenvolveram o projeto “Pagamento por Serviços Ambientais (PSA) na Bacia do Arroio Andréas, RS, Brasil”, denominado “Protetor das Águas”, de 2011 a 2017, tendo como objetivo proteger as nascentes e áreas ripárias da bacia, garantindo a preservação dos recursos hídricos mediante pagamento aos agricultores de pequenas propriedades pelo fornecimento de serviços ambientais de proteção destas áreas, caracterizando-os como “Produtores de Água”. Assim, este artigo aborda a evolução do projeto “Protetor das Águas”, incluindo o diagnóstico das áreas de abrangência e o processo de negociação com os agricultores. Atualmente, o projeto conta com a participação de 63 produtores abrangendo 68 propriedades e totalizando 144,6 ha de áreas preservadas. Pesquisas para avaliar a eficiência da implantação destas áreas de preservação de recursos hídricos verificaram um aumento significativo na diversidade de espécies vegetais e na qualidade da água das nascentes. Desta forma, a adoção do PSA como instrumento de política de desenvolvimento sustentável do território rural, pelos órgãos públicos competentes, torna-se uma alternativa promissora em termos de gestão pública.
Presentación del dossier. Configuraciones de clase, trabajo y capital en América Latina
Authors: Marega Magali , Vogelmann Verónica , Vitali Sofía
Published: January 2019

Presentación del dossier "Trabajo y nuevas configuraciones de clase en América Latina".
Rutin ikinci trimester sonografisinde diastematomiyelinin teşhisi
Authors: ERİŞ YALÇIN Serenat , YAVUZ And , AKKURT Mehmet Özgür , YALÇIN Yakup , ÇINAR Aslım , SEZİK Mekin
Published: January 2019

Diastematomiyeli, spinal kordun yarılmasıyla ortaya
çıkan, fibröz veya kemik bir septum ile ayrılabilen iki hemikord oluşumuna
neden olan, nadir bir okült spinal disrafizmdir. Diastematomiyeli izole
olabileceği gibi, miyelomeningosel, meningosel, spinal lipom, dermal sinüs,
vertebral cisimlerin diğer segmental anomalileri veya viseral malformasyonlar
gibi diğer disrafizmlerle ilişkili olabilir. Bu malformasyonun izole formu iyi
prognoza sahiptir. Bu nedenle, diastematomiyeli saptandığında doğru ebeveyn
danışmanlığı sağlamak için, diğer anomalileri dışlamak adına prenatal
değerlendirme dikkatle yapılmalıdır. Dikkatli sonografik inceleme ile
diastematomiyelinin prenatal tanısı mümkündür. Spinal kanalda ekstra ekojenik
posterior odak saptanması, bu durum için oldukça spesifik bir prenatal
işarettir. MRG, diğer ilişkili malformasyonları dışlamak için faydalıdır. İzole
diastematomiyeli, çok az veya ilişkisiz defisitle ortaya çıkabilir. Burada
rutin ikinci trimester sonografisinde tespit edilen izole bir diastematomiyeli
olgusu sunulmaktadır.
Illumina (post-MR DNA) processing pipeline : mothur v1
Authors: Langlois Kylie
Published: January 2019

This pipeline is for datasets generated from Illumina (2x300) sequencing by MR DNA. MR DNA runs sequences through a proprietary pipeline for quality control of sequences and OTU clustering. This pipeline begins with the OTU abundnace table and utilizes the representative sequence set generated by the MR DNA pipeline. Through trial and error, I have discovered the easiest and best practice for my lab is to use a combination of QIIME (full installation) and mothur. This protocol is the mothurportion. This protocol does not include data visualization. As of 4/5/17, the following versions were used: QIIME v.1.9.1-amd64.vdiand mothur v.1.39.5
Validity of Teaching Materials for Writing Poetry Based on Creative Techniques in Elementary Schools
Authors: Habibi M , Chandra Chandra , Mahyuddin Ritawati , Hendri S
Published: January 2019

One form of literary literacy in elementary schools is that students are able to write poetry. But in reality, students tend to have difficulty making poetry with certain themes. The reason is because teaching materials used were not able to lead students to carry out poetry writing activities well. Therefore, this study aims to develop teaching materials for writing poetry that is valid. The use of various creative techniques is expected to help students in expressing their ideas and imagination into verses of poetry. The research design uses Research and Development with the ADDIE development model. This model consists of the stages of Analysis, Design, Development, Implementation, and Evaluation. Data to determine the level of validity of instructional materials obtained by expert validation and practitioner validation. Validation aspects of teaching materials include: (1) content feasibility aspects, (2) language aspects, (3) presentation aspects, and (4) graphical aspects. Research findings show that teaching materials for poetry writing based on creative techniques are declared valid with an average score of 3.59. Specifically, the scores obtained for each aspect are: (1) content feasibility 3.59, (2) language 3.45, (3) presentation 3.61, and (4) graphical 3.68.
Disfobia.
Authors: MORENO MOLINA DAVID
Published: January 2019

En la presente investigación se categoriza el miedo, el rechazo irracional, hacia un colectivo determinado de la sociedad, como son las personas con diversidad funcional, como disfobia. Para ello, se realiza una profunda revisión histórica acerca del tratamiento hacia las personas con diversidad funcional. Asimismo, el considerable aumento de delitos de odio hacia este colectivo incita a conocer cómo las propias personas que lo padecen lo perciben. Con el objetivo de analizar las percepciones de las personas con diversidad funcional, se lleva a cabo un grupo de discusión. Así, se llega a la conclusión de que la propia sociedad tiene una serie de prejuicios estigmatizantes hacia estas personas, los cuales son, en ocasiones, la causa de la disfobia. Finalmente, debido a la problemática que presenta la disfobia y con el fin de darle una solución, en la medida de lo posible, se plantean una serie de propuestas para paliar dicho problema.
Inclusão Escolar: carências e desafios da formação continuada e atuação profissional docente na inclusão de alunos com deficiência no Ensino Regular e Política Nacional de Educação Inclusiva.
Authors: LOPES DE SOUSA DOMITILIA
Published: January 2019

O presente estudo objetiva apresentar o resultado da pesquisa sobre: Inclusão Escolar: carências e desafios da formação continuada e atuação profissional docente na inclusão de alunos com deficiência no ensino regular e políticas nacional de educação inclusiva no Colégio São José de Caxias – Maranhão – Brasil no ano de 2015. A pesquisa baseou-se nos princípios da abordagem mista. A metodologia adotada para a aquisição dos dados envolveu a observação diária da prática docente, a elaboração e aplicação de questionário e entrevista caracterizando este estudo como uma pesquisa descritiva. Para análise de dados partiu-se da exploração do material coletado. Avaliando os indicadores apresentados através dos dados recebidos quanto a Inclusão Escolar: carências e desafios da formação continuada e atuação profissional docente na inclusão de alunos com deficiência no ensino regular e políticas nacional de educação inclusiva no Colégio São José de Caxias – Maranhão – Brasil no ano de 2015.
Interaction of verbal and graphic image in decoration of the Kyiv-Pechersk Lavra old-printed Akaphistus-books of the 17-18th cc.
Authors: Kurhanova Olena
Published: January 2019

The article explores the development of art decoration tradition in Kyiv-Pechersk Lavra old-printed Akaphistus-books editions of 17-18th cc. The essential elements of art decoration in these Akaphisthus-books are gravures with iconographic images of prayer addressees, corresponding to certain parts of the akaphistus text. The prayer addressee engravings are located in two positions: before or inside of the akaphistus text part. Frontispiece engravings initiate each part of Akaphistus-book. Iconographic posture of prayer addressee in such gravures directs the reader’s attention to the main topic of preceding text – glorification of God, angels or a saint. The frontispiece engraving in Kyiv-Pechersk Akaphistus of the 17th c. are often accompanied with verbal inscriptions, i. e. citations from the well-known church hymns. Quite often baroque poetic texts, which belong to the genre of Ukrainian baroque descriptive poetry, are placed below the frontispiece engraving. Such verbal inscriptions describe images of the engraving, verbalizing the general features of prayer addressee image. The lack of verbal inscriptions on frontispiece engraving in Akaphistus-books of 18th century is compensated by higher quality of the engraving, due to the usage of xylography technique. The image of prayer addressee is frequently used in the center of headset engraving, which precedes the title of each akaphistus text part. The miniatures inside the text part of akaphistus provide visual enrichment of the prayer process. The tradition of small plot illustrations insertion, corresponding to each of the 12 kondaks and ikoses of akaphistus, was initiated by the first Akaphistus editions of 1625 and 1629. This tradition was quite productive during the 17th – early 18th cc. Since the Akaphistus edition of 1731, the miniatures were substituted by engraved initials. The other peculiarity of this edition, which emerged in the subsequent editions of the 18th c., was the usage of engraved frame on each page. Such elements of the artistic decoration enable simultaneous visual and mental perception of akaphistus, declared in introductions to the first Kyiv-Pechersk Akaphistos editions. This masterpiece contamination of verbal and graphic aids in book artistic decoration presents the distinctive feature of the baroque style that influenced the Ukrainian book culture of the 17-18th centuries.