bluuebunny/crossref_metadata_2025 huggingface dataset:
Estimation of the scale parameter in truncated Rayleigh distribution
Authors: Li Jiexiang
Published: November 2023

Abstract
The paper investigated maximum likelihood (ML) estimation of the scale parameter
in truncated Rayleigh distribution (TRD). Some important statistical properties
of MLE for the scale parameter in TRD are derived.

JEL classification numbers: C13, C46, C55.
Keywords: Truncated Rayleigh distribution (TRD), maximum likelihood, Fisher information.
Diplomatic Agents' Privileges and Immunities
Authors: Allan Abu Samra Lama
Published: November 2023

This research examines the extent of diplomatic immunity, specifically in cases where a diplomat commits a criminal offense. This situation raises concerns as it contradicts the fundamental principles upon which diplomatic relations between countries are established, namely, the promotion of economic, social, and cultural ties. The occurrence of such crimes committed by a diplomatic agent undermines the very purpose of fostering these relations. This issue necessitates an investigation into the fundamental characteristics and attributes of diplomatic immunity. It has been observed in global conventions and customary international law that states generally do not relinquish the immunity of their diplomatic representatives, unless the diplomat engages in a non-task-related criminal act, thereby permitting prosecution within the host state's jurisdiction.
A személyes adatok forgalomképessége: párhuzam a személyes adatok helyzete, illetve a sejtek és szövetek jogi szabályozása között
Authors: Turcsiné Czapári Dóra
Published: November 2023

A társadalmi és technikai változásoknak köszönhetően hatalmas és egyre növekvő mennyiségben keletkeznek személyes és egészségügyi adatok. Felismerték a piaci és állami szereplők is ennek jelentőségét, az adatokban rejlő hatalmas potenciált, így egyre nagyobb az igény az adatok felhasználására. A személyes és egészségügyi adatok felhasználása kapcsán megkerülhetetlen a személyes adat jogi természetének, forgalomképességének vizsgálata, hiszen alapjaiban determinálja, hogy lehet-e, illetve milyen típusú szerződés tárgyává tenni. A személyes adatok jogi természetét, illetve forgalomképességét érdemes az emberi sejtek és szövetekre vonatkozó szabályozással párhuzamosan vizsgálni, hiszen az emberi test sejtei és szövetei - így az emberben lévő ivarsejtek és az emberi méhben lévő embriók - kétségkívül az ember alkotórészének, illetve emberi lénynek tekintendők, ezáltal kiterjed rájuk az embert megillető emberi méltóság bizonyos szintig. A személyes adatok védelme is az emberi méltóságból levezethető információs önrendelkezési jogból származik. Az azonos alapvető jogból való levezethetőségük miatt érdemes megvizsgálni, kapcsolódási pontokat keresni a sejtek és a személyes adatok forgalomképességére vonatkozó szabályok között. Ugyanakkor a sejtek és szövetek felhasználása sem általában tilalmazott, hanem a jogalkotó olyan keretek közé szorította, ami egyensúly kialakítását szolgálja az adományozó és recipiens érdekei között.
Avaliação da inibição da nucleosidio trifosfato difosfohidrolase de Trypanosoma cruzi (TcNTPDase1) por compostos sintéticos não naturais derivados da ent-isoquercetina
Authors:   , Ribeiro Isadora Cunha
Published: November 2023

A Doença de Chagas é uma doença tropical negligenciada causada pelo protozoário Trypanosoma cruzi. O arsenal terapêutico para tratamento é muito restrito, com efeitos colaterais importantes e ação limitada dependendo da fase da doença e de variações das cepas do parasito. Sendo é importante o desenvolvimento de novos fármacos. T. cruzi possui em sua superfce uma Ecto-Nucleosídio Trifosfato Difosfohidrolase (E-NTPDase) denominada TcNTPDase1. Já foi demonstrado que a TcNTPDase1 possui papeis importantes para a virulência, infecciosidade e adesão do parasito à célula do hospedeiro mamífero, sendo um potencial alvo para o desenvolvimento de novos medicamentos para tratamento da Doença de Chagas. A quercetina é um flavonóide conhecido por seu papel antioxidante e anti- inflamatório e seu potencial como inibidor de E-NTPDases já foi demonstrado. Este trabalho teve como objetivo a busca de inibidores da TcNTPDase1 recombinante expressa em bactéria. Foram avaliados seis compostos sintéticos (denominados 2, 4, 14, 15, 16 e 17) derivados não naturais da ent-isoquercetina, bem como a quercetina e a miquelianina (derivado natural da quercetina). No capítulo I, apresentamos o artigo que reúne os dados de síntese e de avalição como inibidores desses compostos. A quercetina e miquelianina inibiram a enzima em cerca de 50%. Já 16 apresentou a maior capacidade de inibição (96%) e por cinética enzimática determinou-se inibição do tipo competitiva com Ki de 8,385 µM. Por fim, analisamos a interação do composto 16, o melhor inibidor, com a enzima por docking molecular, verificando o composto 16 interagiu no sitio ativo da enzima e apresentou interações com resíduos considerados importantes para a atividade catalítica da TcNTPDase1. No capítulo II apresentamos a patente “Compostos derivados da ent-isoquercetina, processos de produção e uso como inibidor de NTPDases e em medicamentos para o tratamento da doença de Chagas e Leishmanioses” depositada em maio de 2022. Este trabalho demonstra pela primeira vez que derivados da ent-isoquercetina possuem ação inibitória de ENTPDases podendo ser aplicados no desenvolvimento de fármacos ou de inibidores específicos para uso em terapêutica E- NTPDase alvo dependente.Palavras-chave: Doença de Chagas. E-NTPDases. TcNTPDase1. Inibidores. Quercetina.
Condições de nascimento e fatores gestacionais associados, antes e durante a pandemia da COVID-19, no distrito de Nampula–Moçambique
Authors:   , Alberto Rapieque José
Published: November 2023

Introdução: O peso ao nascer é um indicador com repercussão na saúde e sobrevida infantil, podendo aumentar o risco de morbi-mortalidade no primeiro ano de vida quando este for inferior a 2500 gramas. Durante a pandemia da COVID-19, o setor de saúde viu- se obrigado a ajustar o modelo de assistência às gestantes, afetando adversamente a saúde materna e os resultados perinatais, por conta da adoção de medidas restritivas para contenção da propagação do vírus. Portanto, o estudo objetivou avaliar as condições de nascimento e os fatores gestacionais associados antes e durante a pandemia da COVID-19 no distrito de Nampula-Moçambique. Metodologia: trata-se de um estudo transversal retrospectivo, realizado com dados obtidos nos livros de registro das consultas pré-natal e maternidade, referente ao mês de dezembro dos anos de 2019 (pré- pandêmico), 2020 (fase aguda) e de 2021 (fase amena) em dez centros de saúde do distrito de Nampula. Nas análises a fase pandêmica foi tida como única porque a variável dependente (peso ao nascer) não apresentou diferenças (p>0,05) quando comparado os anos de 2020 e 2021. Foi utilizado o Software Statistical Packege for the Social Sciences (SPSS) versão 20.0. A distribuição das variáveis foi avaliada conforme teste Kolmogorov- Smirnov e a análise descritiva foi por mediana (valor mínimo e máximo). Para comparar as variáveis independentes entre os grupos foi aplicada o Teste Kruskal Wallis com post- hoc de Dunn. A associação foi realizada pelo teste Qui-quadrado de Person (χ2) e teste exato de Fisher com tabela de dupla entrada. A regressão logística binaria foi utilizada para avaliar a associação entre o peso ao nascer e as variáveis preditoras que apresentaram p<0,20 para estimar as razões de chances e intervalos de confiança de 95%, e no modelo final, foram considerado as variáveis que estavam associadas à variável dependente (p<0,05). Resultados: O estudo contou com uma amostra de 761 mulheres e os respetivos neonatos, dos quais 34,2% (n=260) eram referentes ao antes da pandemia da COVID-19 (dezembro de 2019), e os restantes 65,2% (n=501) representaram dois momentos da pandemia, onde 256 são referentes ao ano de 2020 e 245 ao de 2021. Verificou-se associação entre baixo peso ao nascer e a pandemia da COVID-19 (p<0,05), havendo maior prevalência do baixo peso durante a pandemia (10,2%, n=51) quando comparado com o pré-pandêmico (5,8%, n=15). As variáveis preditoras para o baixo peso ao nascer foram o não cumprimento do número mínimo de consulta pré-natal recomendado Ministério da Saúde de Moçambique e a idade gestacional no parto <37 semanas, embora a última tenha se apresentado também antes da pandemia. Conclusão: estudo evidência que a pandemia da COVID-19 impactou no funcionamento do sitemana de saúde, tendo influenciado no aumento da prevalência do baixo peso ao nascer durante a pandemia da COVID-19. Palavras-chave: Peso ao nascer. COVID-19. Pandemia. Prematuro. Fatores gestacionais
STRATEGI COPING STRESS DALAM MENGHADAPI FINANCIAL STRESS PADA MAHASISWA RANTAU (PROGRAM STUDI PSIKOLOGI FIPP UNIVERSITAS NEGERI MANADO) DI TOMOHON
Authors: TAMPI AVRILIA GABRIEL FLORENSIA , LUMAPOW HAROL REFLI , KAPAHANG GLORIDEI LINGKANBENE
Published: November 2023

Tanggung jawab dalam mengelola keuangan sendiri bisa menjadi sumber stress kemudian disebut financial stress. Untuk melewati dan menyelesaikannya, diperlukan strategi coping untuk tetap berefek positif. Tujuan penelitian ini untuk mengetahui faktor-faktor dan strategi coping stress dalam menghadapi financial stress pada mahasiswa rantau. Metode penelitian ini dilakukan menggunakan metode kualitatif dengan pendekatan fenomenologi. Subjek yang diteliti berjumlah 3 mahasiswa rantau pada usia yaitu 18-25 dan teknik pengumpulan data yang digunakan yaitu wawancara, observasi. Hasil penelitian menunjukan bahwa terdapat faktor yang mempengaruhi financial stress mahasiswa rantau yaitu pendapatan orangtua dan literasi keuangan. Kemudian Mahasiswa akan menggunakan strategi coping yang berfokus pada masalah saat mereka memandang situasi tersebut bisa diatasi seperti mencari bantuan seseorang dan mencari solusi. sedangkan strategi coping berfokus pada emosi saat mereka memandang situasi tersebut tidak bisa diatasi. Hal yang akan dilakukan adalah bersikap religius, menciptakan makna positive, menenang diri, membatasi perasaan dan tindakan.
HUBUNGAN TINGKAT PENGETAHUAN IBU DENGAN PEMBERIAN IMUNISASI DASAR PADA BAYI DI PUSKESMAS LAMPASEH BANDA ACEH TAHUN 2023
Authors: Zahra Salsabila Hilmza , Zuheri Zuheri Zuheri , Safirza Satria
Published: November 2023

Imunisasi pada bayi merupakan langkah penting untuk melindungi kesehatan mereka dari penyakit menular yang berbahaya dan mencegah komplikasi serius. Pengetahuan ibu tentang imunisasi lengkap pada bayi memiliki peran krusial dalam menjaga kesehatan dan keselamatan anak-anak. Imunisasi adalah suatu langkah penting dalam upaya pencegahan penyakit menular berbahaya yang dapat mengancam kehidupan bayi. Melalui vaksinasi yang tepat waktu, bayi dapat membangun sistem kekebalan tubuh yang kuat, sehingga dapat melawan infeksi dan menghindari risiko komplikasi serius yang mungkin terjadi pada usia yang rentan. Penelitian ini bertujuan untuk mengetahui hubungan antara pengetahuan ibu terhadap kelengkapan imunisasi dasar bayi. Penelitian ini menggunakan uji chi square yang digunakan untuk melihat hubungan antar dua vairabel. Sampel pada penelitian berjumlah 126 responden. Hasil yang diperoleh penelitian ini adalah tingkat pengetahuan ibu tentang imunisasi 53,2% mempunyai kategori baik, kelengkapan imunisasi pada bayi 55,6% lengkap, dan hasil uji hubungan menunjukkan bahwa adanya hubungan yang signifikan antara pengetahuan ibu terhadap kelengkapan imunisasi pada bayi. Kata kunci: Imunisasi, Pengetahuan Ibu, Kelengkapan imunisasi
Hátráló globalizáció? : A nemzetközi kereskedelmi rendszer változásai
Authors: Goreczky Péter
Published: November 2023

Kína felemelkedése és rivalizálása az USA-val, illetve az Egyesült Államok megváltozott kereskedelempolitikája egyaránt olyan fejlemény, amely eltereli eddigi pályájáról a nemzetközi kereskedelmi rendszert. Az elemzés ezt a két tényezőt vizsgálva keresi a választ arra, kialakulhat-e az USA és Kína körül két, egymástól elkülönülő kereskedelmi blokk, illetve milyen irányba fejlődhet tovább a nemzetközi kereskedelmi rendszer. A kereskedelem stratégiai fontosságú szegmenseiben a két nagyhatalom elkezdett leválni egymásról, ám egyelőre alapvetően csak USA–Kína kétoldalú jelenségről lehet beszélni. A washingtoni vezetők is egyértelművé tették, hogy a két gazdaság teljes elhatárolása mindkét országra nézve katasztrofális következményekkel járna, ezért a világgazdaság két, elkülönült kereskedelmi blokkra történő szétválására tehát jelenleg nincs komoly esély vagy lehetőség. A világkereskedelem jövője szempontjából jelenleg a fő veszély az, hogy a két legnagyobb kereskedőország rivalizálása szétzilálja az évtizedek óta működő kereteket. A hagyományos szabadkereskedelmi egyezményekből kiábrándulva Washington új, innovatív, nemzetközi gazdasági partnerségekben és egyfajta „minilateralizmusban” látja a jövőt. A kereskedelem liberalizációjának és az állami beavatkozás mérséklésének korszakához egy, az amerikai elképzelések mentén megreformált WTO sem jelentene visszatérést.
Analisis Pengaruh Pengalaman Wisata yang Berkesan (Memorable Tourism Experience) terhadap Destination Loyalty
Authors: Nugraheni Veronica Febriana , Dirgantara I Made Bayu
Published: November 2023

Tourism is an activity to eliminate excessive satiety from daily activities. As an effort to eliminate satiety, tourism can be said to be a necessity for every individual. This is a good opportunity for tourism sector entrepreneurs to develop their business. In an increasingly developing era, competition in the tourism business sector is getting tighter. Business managers must have the right strategy to be able to survive and compete with their competitors. The goal to be achieved is to be able to create tourists who are loyal to the destinations they manage. Therefore, this research focuses on the factors that influence loyalty to a destination which can lead to business success. The aim of this research is to analyze the influence of memorable tourist experiences, destination image, place attachment on destination loyalty in the Semarang Old City area. The number of samples used in this research was 150 tourist respondents who had visited the Semarang Old City area. The data collection method was carried out by distributing questionnaires online and analyzed using the Structural Equation Modeling (SEM) method using the Analysis Moment of Structural (AMOS) 22 program. The results of the analysis showed that memorable tourist experiences, destination image and place attachment had a positive and significant influence towards tourist loyalty (destination loyalty).
Review Studies Key Element of Agrotourism Management
Authors: Utama I Gusti Bagus Rai
Published: November 2023

This research seeks to formulate a definition and try to find the key success factors for agrotourism management, especially in Indonesia. Agrotourism helps to preserve local agriculture by providing a new source of income for farmers and encouraging the consumption of locally grown produce. Agrotourism can help diversify rural economies by creating new jobs in hospitality, food service, and transportation. Agrotourism promotes sustainable tourism by encouraging visitors to experience local culture and traditions, while also respecting the environment and supporting local communities. One successful practice in Agrotourism Management is offering farm-to-table experiences. This involves inviting guests to participate in the production and preparation of food, and then serving it on-site. This not only provides a unique experience for visitors, but also helps to promote local agriculture and support small businesses. Another effective practice is creating partnerships with other local attractions and businesses. By working together, agrotourism destinations can offer visitors a more comprehensive and appealing experience. For example, a winery might partner with a nearby bed and breakfast to offer a wine-tasting package that includes overnight accommodations. In conclusion, Agrotourism Management is a crucial aspect of sustainable agriculture and rural development. By promoting responsible tourism activities on farms and ranches, we can create economic opportunities for farmers and local communities while preserving the natural environment.
Pengaruh Country of Origin terhadap Minat Beli Produk Skincare Wajah Korea Selatan dengan Persepsi Kualitas Produk sebagai Mediasi: Studi Kasus pada Mahasiswi Universitas Yapis Papua
Authors: Suratini Suratini , Indahlia Indahlia , Nur Imran S.M.
Published: November 2023

This research aims to determine the influence of Country of Origin on Consumer Purchase Interest with Product Quality Perceptions as mediation among female students at Yapis University, Papua. The population in this study were female students from the Faculty of Economics and Business, Yapis University, Papua, with a total sample of 162 samples. This research uses a proportional sampling technique. The data collection method was carried out by distributing online questionnaires via Google Form. Respondents' attitudes were measured using an interval scale with two extreme categories. The data obtained was processed using quantitative analysis techniques with the help of the Amos for Windows version 24 program. The results of this research show that the country of origin variable has a positive and significant effect on the perception of the quality of Korean facial skincare products. Furthermore, the influence of country of origin on buying interest was found to be positive. Perception of product quality has a positive and significant effect on purchase intention. The country of origin variable has a positive and significant effect on purchase intention through perceptions of the quality of South Korean facial skincare products among FEB students at Yapis University, Papua.
Pengaruh Label Halal terhadap Keputusan Pembelian Produk Makanan Mie Samyang melalui Kepercayaan Konsumen sebagai Variabel Mediasi: Studi Kasus pada Mahasiswa/i Muslim di FEB Universitas Yapis Papua
Authors: Pasolo Fahrudin , Sari Firdi Fadilah Permata
Published: November 2023

Halal labeling is a label that informs consumers of the labeled product, that the product is truly halal and the ingredients it contains do not contain elements that are prohibited by sharia so that these products can be consumed by consumers. Thus, products that do not include a halal label on their products are considered not to have received approval by the authorized institution (LPPOM-MUI) to be classified as halal products or are considered doubtful about their halalness. The halal label is important because it is useful for providing confidence to consumers in the decision-making process. This study aims to determine the effect of halal labeling on purchasing decisions mediated by consumer confidence. This research method is quantitative research with 113 respondents. The data collection method was carried out through distributing online questionnaire links to respondents. The results showed that halal label has a positive and significant effect on purchasing decisions, halal label has a positive and significant effect on consumer confidence, consumer confidence has a positive and significant effect on purchasing decisions, halal label has a positive and significant effect on purchasing decisions for food products through consumer confidence as a mediating variable, consumer confidence is significant to be a mediating variable between halal labels on purchasing decisions.
Pengaruh Technology Acceptance Model (TAM) terhadap Repurchase Intention dimediasi oleh Trust pada Pengguna Facebook Marketplace
Authors: Giantari I Gusti Ayu Ketut , Pamungkas Pamungkas , Putra I Nengah Subawa Kardika , Mahendra I Made Gilang
Published: November 2023

The rapid growth of online stores drives intense competition in the e-commerce industry. Maintaining customer loyalty and retention in e-commerce platforms can be quite challenging. This study aims to determine the influence of perceived ease of use and perceived usefulness on repurchase intention, mediated by trust, in the Facebook Marketplace application. The research was conducted in Denpasar with 118 respondents. Data collection was performed using Google Forms questionnaires, and the data was analyzed using Partial Least Squares (PLS) analysis. The results indicate that perceived ease of use does not have a positive and significant impact on trust and repurchase intention. Similarly, perceived usefulness does not have a positive and significant effect on trust and repurchase intention. However, trust has a positive and significant influence on repurchase intention. Perceived ease of use and perceived usefulness do not significantly affect repurchase intention among Facebook Marketplace users in Denpasar, Bali, when mediated by trust.
Effects of Empowerment Procedures on Clients’ Livelihoods Sustainability: A Case of Deposit Taking Microfinance Institutions in Nakuru County, Kenya
Authors: Karimi Catherine , Koome Dr. Peter , Gesimba Dr. Paul
Published: November 2023

The Microfinance institutions (MFIs) clients’ livelihoods sustainability largely relies on the institutions managerial functions whose aim is to achieve the vision of poverty alleviation through encouraging the poor people to save and get loans in order to begin or enhance their small businesses thus improve their living standards as well as achieve livelihoods sustainability. The study explored the relationship that exists between deposit taking MFIs empowerment procedures on clients’ livelihoods sustainability in Nakuru County, Kenya. The problem of the study is that lack of client’s comprehensive empowerment procedures by the deposit taking MFIs, leads to poor business management and failure to repay the borrowed loans leading to auctioning of their assets. The theory adopted for the study was the agency theory and the resource dependence theory. The study adopted mixed research method. The sample size consisted of 580 MFIs clients and 10 managers out of 1,954,111 target population. The Primary data was collected through the use of questionnaire and the interview. For quantitative analysis the study utilized descriptive statistics to describe the study’s variables characteristics, cross tabulation and chi-square analyses were used to establish the relationship between the independent and dependent variables. The data was presented using tables. The study found out that majority of the MFI clients were women whose highest level of education was primary level. Savings, client representation in management, training time and content and mode of borrowing were found to have a significant relationship with clients’ livelihoods sustainability. The study recommends that the MFIs need to focus on vibrant and continuous empowerment programs.
Level of Readiness of Education Students for Hy Flex Modality
Authors: Jr. Sergio D. Mahinay , Ramirez Sophia Mariefer G. , Rojo Precious Ferly Mae V. , Gama Donna Saira L. De , Viloan Camille R.
Published: November 2023

The core of this research is the readiness of education students for HyFlex learning modality. It made use of the descriptive-correlational research design to describe their readiness for this modality of learning in terms of knowledge, skills, attitude, and values; and to establish the strength and direction of the relationship between these variables. This study was conducted at Notre Dame of Midsayap College during the academic year 2022-2023. It included forty-two Bachelor of Secondary Education students as respondents who were enrolled in the college at any given time during the conduct of the study. They were eighteen to twenty-five years old and were comprised of thirty-five females and seven males. Findings revealed that the respondents had the basic and necessary resources for the operation of HyFlex learning modality including possession of electronic communication devices such as android/smartphones and laptops; provision of internet connections such as pre-paid mobile/WIFI data and PLDT/DSL; and familiarity with virtual platform applications such as ZOOM, Class In, Schoology and Google Meet. The respondents had high level of readiness for the adoption of HyFlex learning. In terms of knowledge, they knew much about this modality as one involving face-to-face, synchronous online, and asynchronous online classes, and as one needing stable internet connections to be carried out effectively. In terms of skills, they could share and receive information using the internet, and could participate in a chat space along with the live video of the class session. In terms of values, they held on to the principles that students must maintain a balance between studying and taking care of their family, and that they should be given flexibility in accomplishing their tasks. In terms of attitude, they believed in the timeliness of HyFlex learning modality especially this time of climate change, and they were interested in participating in class discussions either online or face-to-face. Finally, there is a strong and positive relationship between skills and knowledge, and attitude and values, and that relationship is highly significant.
Bioinformatics Analysis Identifies Potential Hub Genes, Therapeutic Agents, and Crucial Pathways in the Pathogenesis of Refsum's Disease
Authors: Sharma Ravinder , Bhullar Anant , Bansal Parveen , Kaur Gunpreet , Gupta Vikas
Published: November 2023

Refsum Disease is a infrequent, inherited, autosomal recessive condition. The purpose of this study was to investigate prospective therapeutic drugs to cure Refsum disease and to determine the critical genes/pathways through bioinformatics analysis. Using the text mining method, Refsum disease-related genes were discovered and MCODE plugin, GO & KEGG analyses was used to examine modules. A PPI network was created by STRING and visualized in Cytoscape. Drug-gene interactions were investigated using the drug-gene interaction database. Using the text mining of gene (TMG) method, 64 distinct genes in Homo sapiens linked to Refsum illness. There were 71 edges and 48 nodes in a PPI network. 13 hub node genes were discovered using a cluster analysis of filtering nodes. The genes were then significantly elevated in protein trans-membrane transport, protein import to the peroxisome matrix and fatty acid beta-oxidation, according to the enrichment analysis. We discovered that two already-approved medications could target two of the 13 chosen genes. The findings revealed the hub genes for Refsum illness to be SLC27A2, AGXT, GNPAT, CRAT, HSD17B4, AMACR, CAT, SCP2, PEX13, PEX10, PEX1, PEX7, and PEX2. Additionally, Ibuprofen and alcohol were named as prospective therapeutic agents for the management and therapy of Refsum’s illness. Only bioinformatics tools were used in this study further in-vitro and in-vivo studies are required because phenotypic differences will vary from person to person depending on the expressivity of the gene.
 
Received: 9 August 2023 | Revised: 16 October 2023 | Accepted: 20 November 2023
 
Conflicts of Interest
The authors declare that they have no conflicts of interest to this work.
 
Data Availability Statement
The data that support this work are available upon reasonable request to the corresponding author.
Influence of Raw Material Size on the Microstructure of Graphene Oxide and Its Early Strengthening Properties of Cemen
Authors:   School of Materials Science and Engineering, Shenyang Jianzhu University, Yu TONG , Yahe CUI ,   School of Materials Science and Engineering, Shenyang Jianzhu University, Xiangqun DING ,   School of Materials Science and Engineering, Shenyang Jianzhu University, Mingyu ZHAO ,   School of Materials Science and Engineering, Shenyang Jianzhu University
Published: November 2023

With the purpose of exploring the influence of raw material size on the structure-performance of graphene oxide (GO) for cement reinforcement, this paper used natural flaked graphite with different particle sizes as raw material to prepare GO nanosheets by a method of enhanced Hummers, and then used scanning electron microscope (SEM) , X-ray diffraction (XRD) , Raman spectrum, infrared spectrum (IR) and other means to characterise the microstructure of GO products in detail, and then investigated the effects of raw material size and graphene oxide GO dosage on its early strengthening effect in cement. The experimental results showed that with the decrease of raw material particle size, the spacing between the layers of GO products is basically the same, while the oxidization degree is increased, and the oxygen-containing groups on the surface are increased. When the GO matt was used to prepare cement mortar with same GO extent, the mechanical strengths at an age of 3 days were found to initially increase and then decrease with the reduction of raw material particle size, and the GO products had the best effect on the improvement of early mechanical strength of cement when the raw material particle size was 13μm. On the other hand, GO matt being obtained from the raw material particles in a size of 13μm was employed to prepare cement mortar with different GO content, of which the 3d strength was found to increase apparently with the increasing GO content, and thus resulted in the increment of 8. 85% to the 3d compressive strength and 6. 34% to the 3d flexural strength for the mortar specimen obtained with a GO content of about 0. 05%, but the further increasing of the GO content is not proposed, which might gave rise of a relative low mechanical strength.
Creating a Smart Safety Device for Women using IoT
Authors: Dr. Gholap P. S.  , Saurabh Pansare  , Shrikant Khote  , Rushikesh Ambalkar  , Vedant Nalawade
Published: November 2023

Would it be moral if I said that even in today's 2020, women in our society cannot live independently? Every day there is a lot of news of physical violence, rape and violence against women, and this number is increasing, especially in big cities. The presence of CCTV helped to some extent but the suspect could not be identified at the time of the attack. The aim of this article is to enable women to use technology to become self-sufficient, thereby reducing crimes against women and girls in India. The application proposal reveals a practical, effective and portable product that can help women live safe, independent lives. The goal of the Internet of Things is to integrate everything we have created and implemented with SIM 800 GSM modules, force sensitive resistors, impact sensors, Bluetooth modules, LCDs, resistors, transistors, diodes, LEDs, Arduino UNO, buzzer, etc., PCB, breadboard, transformer, switch, Arduino compiler and Neo6mv2 GPS module. The proposed system has dual security where a sick woman can seek help and share her location through the emergency number. It can activate the system in three different modes depending on the situation required, and sometimes it seems to appear at strange or bad times. The victim can activate the device using the alarm button or Bluetooth module. The internal heart rate sensor, GPS module and GSM module will be automatically activated when the device is turned on. The device will constantly beep so neighbors know what's going on, police said. The device is equipped with a force-sensitive resistor to protect the device from any external force during any misbehavior or misuse. In the age of pepper spray and smart bracelets, such tools have become powerful and effective in separating women's lives from bad behavior
Farm Help : A Real Time Mediator Between Service Provider and Farmer
Authors: Subodh Walke  , Shubham Nagargoje  , Rushikesh Rakh  , Rushikesh Gadge  , Prof. Vilas Joshi
Published: November 2023

Several reasons have been evicted as the major concern behind the farmer’s apathy, specifying like scarcity, dues and marketing. However intermediate complication is major difficulty at the present days, in order eliminate the concept of middlemen this application is constructed. Improving the effectiveness and efficiency of agricultural marketing necessitates a comprehensive and cooperative strategy involving farmers, intermediaries, researchers, and administrators. The mounting difficulties faced by farmers, including insufficient financial backing, limited job opportunities, and the absence of proper equipment and machinery, are causing a substantial decline in the nation's agricultural sector. Reversing this trend requires a united effort to tackle the complex challenges affecting the industry.
MODELO MATEMÁTICO DE LA DINAMICA DE TRANSMISIÓN DE LA INFLUENZA MEDIANTE AUTOMATAS CELULARES
Authors: Trujillo-González Julio , Martínez Valderrama Iveth Verónica
Published: November 2023

Este estudio analiza el uso de autómatas celulares (AC) para simular la propagación de la influenza. A pesar de la falta de datos específicos para Panamá, los resultados mostraron que los AC pueden ofrecer una representación precisa y detallada de la dinámica de propagación de enfermedades en el ambiente. Se observó una correspondencia razonable con los modelos continuos, subrayando su potencial para predecir y controlar epidemias, las cuales derivan en un incremento en el uso de los servicios de salud y, por ende, un mayor consumo energético que se traduce en emisión de más contaminantes ambientales. El estudio también enfatizó la necesidad de disponer de datos epidemiológicos precisos y actualizados, ya que son cruciales para la eficacia de los modelos. Esta investigación destaca el valor de los AC en la modelización de enfermedades y la importancia de los datos robustos para el desarrollo de políticas de salud pública eficaces.
Influence of patient trust in provider and health literacy on receipt of guideline-concordant chronic opioid therapy in HIV care settings
Authors: Williams Emily C. , Frost Madeline C. , Lodi Sara , Lira Marlene C. , Tsui Judith I. , Lunze Karsten , Kim Theresa , Liebschutz Jane M. , Del Rio Carlos , Samet Jeffrey H.
Published: November 2023

Objective: Persons with HIV (PWH) frequently receive opioids for pain. Health literacy and trust in provider may impact patient–provider communication, and thus receipt of guideline-concordant opioid monitoring. We analyzed baseline data of HIV-positive patients on chronic opioid therapy (COT) in a trial to improve guideline-concordant COT in HIV clinics.

Design: Retrospective cohort study.

Setting: Two hospital-based safety-net HIV clinics in Boston and Atlanta.

Patients and participants: A cohort of patients who were ≥18 years, HIV-positive, had received ≥ 3 opioid prescriptions from a study site ≥21 days apart within a 6-month period during the prior year and had ≥1 visit at the HIV clinic in the prior 18 months.

Main outcome measures: Adjusted logistic regression models examined whether health literacy and trust in provider (scale scored 11-55, higher indicates more trust) were associated with: (1) ≥ 2 urine drug tests (UDTs) and (2) presence of an opioid treatment agreement.

Results: Among 166 PWH, mean trust in provider was 47.4 (SD 6.6); 117 (70 percent) had adequate health literacy. Fifty patients (30 percent) had ≥ 2 UDTs and 20 (12 percent) had a treatment agreement. The adjusted odds ratio (aOR) for a one-point increase in trust in provider was 0.97 for having ≥ 2 UDTs (95 percent CI 0.92-1.02) and 1.03 for opioid treatment agreement (95 percent CI 0.95-1.12). The aOR for adequate health literacy was 0.89 for having ≥ 2 UDTs (95 percent CI 0.42-1.88) and 1.66 for an opioid treatment agreement (95 percent CI 0.52-5.31).

Conclusions: Health literacy and trust in provider were not associated with chronic opioid therapy quality outcomes.
Nonprescription use of buprenorphine tablets among patients at a tertiary care addictive disorder treatment center in India: Observations and implications
Authors: Balhara Yatan Pal Singh , Saha Priyanka , Mathew Merlin , Kumar Mukul , Parmar Arpit , Lal Rakesh , Sarkar Siddharth
Published: November 2023

Objective: Nonprescribed use of drugs is a clinical and public health challenge fueled by diversion of controlled opioids like buprenorphine. In this study, we report the nonprescription use of buprenorphine and buprenorphine–naloxone for the first time in India.

Design: A cross-sectional observational study utilizing semistructured interviews.

Setting: A tertiary care addictive disorder treatment center in India, which provides inpatient and outpatient medically oriented care that includes agonist treatment (buprenorphine) or detoxification and antagonist treatment (naltrexone).

Participants: Patients aged 18-65 years, registered at the center, and who had a history of current (within the past 6 months) nonprescription use of buprenorphine tablets were recruited.

Main outcome measures: Participants were questioned about demographic and clinical factors and details of nonprescription use of buprenorphine and buprenorphine–naloxone using a structured questionnaire. Since both buprenorphine with naloxone and buprenorphine without naloxone are available and transacted on the street “loose” out of the blister packs, we were unable to differentiate the use of plain buprenorphine and a combination of buprenorphine–naloxone.

Results: A majority of the participants used nonprescribed tablets buprenorphine and buprenorphine–naloxone with an intent to control the withdrawal symptoms, and the reason for this use was that other patients shared their prescriptions of these medications. About half of the participants injected the tablets, and liquid pheniramine was most commonly used as the solvent for dissolving the tablets. A “high” was perceived by around half of those who injected. Participants reported knowing, on an average, around 13 peers who injected the tablet buprenorphine or buprenorphine–naloxone.

Conclusion: Nonprescription use of tablets buprenorphine and buprenorphine– naloxone is a clinical concern and also an important public health issue. Geographical and systemic expansions of the availability of buprenorphine may reduce the “demand” for nonprescribed buprenorphine, while the opportunities for diversion from treatment centers can be minimized through more careful clinical prescriptions and monitoring practices.
Volume 19, Number 5
Authors: Opioid Management Journal of
Published: November 2023

September/October 2023
Analisis kualitas nutrisi kulit buah nanas (Ananas comosus L) yang difermentasi dengan starter berbeda sebagai pakan ruminansia
Authors: Adam Koji Al , Samadi Samadi , Wajizah Sitti
Published: November 2023

Tujuan penelitian ini adalah untuk mengevaluasi kualitas fermentasi kulit nanas dengan menggunakan starter yang berbeda. Penelitian ini dilaksanakan di Laboratorium Ilmu Nutrisi dan Teknologi Pakan, berlangsung selama 1 Agustus hingga 3 Oktober 2018. Penelitian ini menggunakan kulit nanas yang telah dikeringkan. Rancangan yang digunakan adalah Rancangan Acak Lengkap terdiri dari 4 perlakuan dan 4 ulangan, sehingga diperoleh 16 unit percobaan. Perlakuan dalam penelitian ini terdiri dari P0 (kontrol/tanpa pemberian starter), P1 (penggunaan starter EM-4), P2 (penggunaan starter SBP), dan P3 (penggunaan starter Probion). Parameter yang diamati meliputi pH, BK (bahan kering), SK (serat kasar), LK (lemak kasar), PK (protein kasar), Abu, BETN (bahan ekstrak tanpa nitrogen). Data yang diperoleh dianalisis dengan menggunakan sidik ragam (Analisis of Variance/ ANOVA). Hasil penelitian menunjukkan bahwa pemberian starter yang berbeda EM-4, SBP dan Probion dalam fermentasi kulit nanas tidak berpengaruh nyata (P>0,05) terhadap SK, Abu, BK, dan BETN dan berpengaruh nyata (P<0,05) terhadap pH, LK, dan PK.
Potensi pengembangan agroforestri di Desa Tapango, Kabupaten Polewali Mandar melalui pendekatan SWOT Analysis
Authors: Amiluddin Amiluddin , Manggabarani Ishak , Siadina Siadina
Published: November 2023

Agroforestri (Wana Tani) merupakan suatu pengelolaan pemanfaatan lahan secara optimal dan lestari, melalui perpaduan antara kegiatan kehutanan dan pertanian dalam unit-unit pengolahan sosial, ekonomi dan budaya masyarakat. Penelitian ini bertujuan untuk mengidentifikasi peluang usaha agroforestri dan strategi yang dapat diterapkan dalam pengembangan agroforestri di Desa Tapango Kecamatan Tapango Kabupaten Polewali Mandar. Metode yang digunakan dalam penelitian ini adalah analisis SWOT dengan matriks IFAS (Internal Factor Analysis Summary) dan EFAS (External Factor Analysis Summary) untuk mengidentifikasi faktor lingkungan eksternal dan internal yang menjadi kekuatan, kelemahan, peluang dan ancaman pengembangan Agroforestri. Untuk menganalisis strategi potensi pengembangan Agroforestri yaitu faktor internal memiliki faktor kekuatan dengan nilai total 1,69 lebih kecil dari faktor kelemahan dengan nilai total 1,87. Hal ini menunjukkan bahwa kekuatan usaha Agroforestri ini lebih sedikit dibandingkan kelemahannya. Sedangkan faktor eksternal memiliki faktor peluang dengan nilai total 1,85 lebih besar dari faktor ancaman dengan nilai total 1,70, hal ini menunjukkan bahwa potensi peluang pengembangan agroforestri sangat besar. Hasil analisis potensi pengembangan agroforestri berada pada kuadran III (Turn Around) yang menunjukkan strategi terfokus pada aspek potensi pengembangan agroforestri dengan strategi W-O (Weakness-Opportunity), memanfaatkan peluang dan mengubah kelemahan menjadi kekuatan tersendiri. Pelaku usaha harus meningkatkan pendekatan kepada LSM atau pemerintah dan meningkatkan kualitas produksi.
The Impact of Educational Technology on Distance Learning in The Era of Post-Covid-19
Authors: Mohamad Noor Nurdayana
Published: November 2023

E-learning is a type of electronic educational technology that enables online or distance learning to become the norm even before the COVID-19 era. It is a depiction of convergent products, services, and activities that have emerged in the digital media space and are thought to be more efficient at delivering learning and content, resulting in time and cost savings, and having a smaller negative impact on the environment. Based on existing research, the problem area of this study is to understand how technological convergence provides opportunities to promote the convenience of distance learning and its effect on society, as well as the barriers to the idea remaining implemented post-COVID-19. This paper collects data through a semi-systematic literature review based on similar themes which are educational technology, distance learning, and education during and post COVID-19. The primary objectives of this article are to analyse and discuss the impact of educational technology, as well as to discuss the implications of distance learning, particularly after the world was compelled to embrace it during the COVID-19 lockdown. In summary, it appears that educational technology is growing more interactive, mobile, immersive, and ubiquitous in the second decade of this twenty-first century. The development of digital platforms and tools, the availability of digital content to adult professionals, and self-paced continuous learning appear to be the key components of the learning of the future. Although numerous challenges such as infrastructure and internet must be addressed, distance learning has a bright future, and e-learning is the most effective tool for achieving it. More research is needed to shed light on educational technology as a product of technological convergence, which is not only about unification and commonality but also about divergence in various aspects and opportunities.
Using TED Talks Videos to Improve Speaking Skills Among Secondary Students in Kota Kinabalu, Sabah
Authors: FENG TIAN YI , Said Noraini
Published: November 2023

This study investigates the incorporation of TED Talks videos as a pedagogical tool in secondary language instruction, with a specific emphasis on improving speaking fluency and students' attitudes toward learning. By recognizing the increasing importance of multimedia in language acquisition, the research aims to uncover the tangible benefits of integrating TED Talks videos into language lessons. Utilizing a quasi-experimental design with control and experimental groups, the study combined quantitative analysis of pre-tests and post-tests with qualitative insights gathered from a Likert questionnaire. The outcomes strongly indicated that students exposed to TED Talks videos exhibit significant advancements in their as indicated by the significant mean value of post-test scores between the experimental and control groups. Additionally, the research highlights the pivotal role of authentic materials in enhancing motivation and fostering positive learning attitudes. This research also delved into the wider implications of these findings for language instruction, underscoring the potential of multimedia resources to revolutionize conventional teaching methodologies. Beyond the classroom, the research envisions an education landscape where innovative techniques, such as the incorporation of TED Talks videos, reshape language teaching. By addressing pedagogical and motivational facets, the study advocates for contemporary resources to create engaging and effective learning experiences. The research encourages educators to explore how multimedia interacts with diverse learners and cultural contexts, ultimately promoting dynamic instructional approaches aligned with evolving educational needs.
Spatial and seasonal variations in surface water quality of the Lower Kinabatangan River Catchment, Sabah, Malaysia
Authors: Harun Sahana , Dambul Ramzah , Abdullah Mohd. Harun , Mohamed Maryati
Published: November 2023

Surface water quality was examined to determine spatial and seasonal variations in the Lower Kinabatangan River catchment, Sabah, Malaysia between October 2004 and June 2005, during the weak La NiÃ±a event. The study sought to distinguish between the quality in surface waters draining from an oil palm plantation (OP), a secondary forest (SF) and an oxbow lake (OB); and to identify its seasonal variability. A total of 45 samples were collected during fieldwork campaigns that spanned over the inter-monsoonal period, wet and dry seasons. The Water Quality Index (WQI) was calculated and analysed based on the Malaysia Interim National Water Quality Standard (INWQS). Results show that the quality of the river fall into Class II or moderate level. Discriminant analysis (DA) has been employed to classify independent variables into mutually-exclusive groups. Suspended sediment (SS) and chemical oxygen demand (COD) parameters were found higher during the wet season. COD was found dominant in stream located within the oil palm plantation, whilst SS was dominant in oxbow lake. Surface water quality variations could be influenced by weak La NiÃ±a event in 2005/2006, as precipitation anomalies have been observed during the sampling campaign.