bluuebunny/crossref_metadata_2025 huggingface dataset:
De La Saison à Estação: a tradução como forma de representação cultural na imprensa feminina do século XIX
Authors: Silva Beatriz Romero da , Deângeli Maria Angélica
Published: June 2022

Este trabalho tem por objetivo analisar o periódico feminino francês La Saison (1867-1909) e sua tradução para o português, A Estação (1879-1904), sob um viés linguístico e cultural, com base em uma perspectiva que, segundo Crépon (2016), pressupõe que toda cultura é constitutivamente o resultado de uma tradução ou de uma sucessão de traduções. Tencionamos, assim, verificar como a tradução da imprensa feminina francesa foi determinante para a constituição da imagem e dos costumes da mulher brasileira no século XIX, uma vez que a cultura disseminada no Brasil da época era importada da Europa, sobretudo, por meio da imprensa e de sua tradução.Palavras-chave: tradução cultural; imprensa feminina; identidades; La Saison; A Estação.
Alfabetização e letramento de surdos: mapeamento das contribuições de pesquisas
Authors: Barbosa Marcela Gomes , Maria Alves Cavalcanti Wanilda , Pastor de Andrade Sousa Wilma
Published: June 2022

O presente artigo tem como objetivo analisar as contribuições de pesquisas realizadas, entre os anos de 2000 e 2019, acerca da alfabetização e do letramento de surdos na Biblioteca Digital Brasileira de Teses e Dissertações (BDTD). Adotamos, como referencial teórico, Cavalcanti (2011), Cárnio, Couto e Lichtig (2000), Fernandes (2006), Quadros e Schmiedt (2006), Lacerda, Albres e Drago (2013), Soares (2003), Sousa (2014) Sousa e Mourão (2018), entre outros. Optamos pela pesquisa qualitativa, e os dados coletados totalizaram vinte e sete trabalhos. Para a análise dos dados, utilizamos o procedimento metodológico da análise de conteúdo de Bardin (2016). Os resultados nos mostraram poucas pesquisas nessa base de dados abordando a temática proposta, todavia foram encontradas diversas contribuições para a educação bilíngue de pessoas surdas, priorizando atividades escolares e experiências baseadas nos aspectos visuais.Palavras-chave: educação bilíngue de surdos; formação de professores; leitura e escrita.
Discurso e(m) re(x)istência no/pelo digital: memórias de um acontecimento e a arte em rede
Authors: Ruiz Marco Antonio Almeida
Published: June 2022

Este artigo tem como objetivo apresentar um gesto de interpretação acerca do efeito de re(x)istência criado em alguns memoriais virtuais irrompidos durante a pandemia da Covid-19 no Brasil. Mais especificamente, observamos a instauração de novas memórias sobre o morrer e o luto ressignificadas pela arte em perfis da rede social Instagram, tais como: Museu do Isolamento e Inumeráveis. Trata-se de desconstruir a naturalização imposta pelas estatísticas e singularizar as características dos sujeitos vítimas da doença, ressaltando as suas subjetividades, não como números e gráficos oficiais, mas como amores e entes queridos, brasileiros e brasileiras, que perderam a vida por conta dessa doença. Para estas nossas reflexões, partimos dos pressupostos teórico-metodológicos da análise do discurso francesa, em especial as noções de memória e acontecimento de Michel Pêcheux (2008, 2010).Palavras-chave: arte; acontecimento; discurso, re(x)istência; pandemia.
Habilidades afetivas em livros didáticos: o gerenciamento tensivo do gosto pela leitura
Authors: França Poliana Sabina Quintiliano Silvesso de
Published: June 2022

Este trabalho tem como objetivo discutir as estratégias utilizadas em duas seções do livro destinado ao 6º ano escolar da coleção Way to English (TAVARES; FRANCO, 2020) para a disciplina de Língua Inglesa. Interessam-nos as estratégias que dialogam com o domínio afetivo da aprendizagem. Em relação aos objetivos afetivos, dispostos na Base Nacional Comum Curricular (BNCC), as reformulações dos livros didáticos, ocorridas nos últimos três anos, visam estabelecer vínculos com eles. Para esta discussão, exploramos a habilidade “interessar-se pelo texto lido” (EF06LI12), conforme disposta na BNCC. Elegemos a Semiótica Tensiva, fundamentada por Zilberberg (2011), desdobramento teórico da Semiótica Discursiva, como ferramenta teórico-metodológica. Da mesma forma, partimos do esquema afetivo proposto por Bloom, Krathwohl e Masia (1982), uma classificação de objetivos educacionais do campo.Palavras-chave: semiótica tensiva; ensino; BNCC; livro didático; competências socioafetivas.
Monitoring of the principles of awards law of the Russian Federation subjects
Authors: Kabanov P. A.
Published: June 2022

Objective: to assess the state of legal regulation of award relations in the Russian Federation subjects and to develop measures

to improve it.

Methods: the main methods of the conducted research are general scientific methods of cognition: analysis, synthesis, comparison, extrapolation, and the specific-legal methods of cognition of award relations based on them, used in the Russian theory of law and the state.

Results: the knowledge about the legal regulation of award relations in the Russian Federation subjects is systematized; the features of the legal regulation of the higher official (state) regional awards system formation and application by the legal norms of the Russian Federation subjects are identified. Typical shortcomings of the constitutional and legal regulation of award relations in individual Russian Federation subjects are revealed: on the one hand, the lack of consolidation of the regional awards institution within the constitutional (statutory) legislation, and on the other hand, excessive detailing of award relations in regional constitutions and statutes, which is to be reflected in the norms of special regional award legislation. Measures are proposed to eliminate the identified shortcomings and improve the constitutional and legal regulation of award relations in the Russian Federation subjects.

Scientific novelty: for the first time in the Russian legal science, a monitoring study of the principles of award law of the Russian Federation subjects was conducted, which allows assessing the quality of legal regulation of award relations in the Russian regions.

Practical significance: the results obtained can be used in the law-making activities of state authorities of the Russian Federation subjects to improve the legal regulation of award relations.
Early-stage Phishing Detection on the Ethereum Transaction Network
Authors: Wan Yun , Xiao Feng
Published: June 2022

As cryptocurrency is widely accepted and used, illegal activities based on it have also attracted attention, especially phishing scams, which bring great losses to both customers and countries. Therefore, early-stage detection of this behavior is of great significance, as it can minimize users’ losses when a phishing scam is ongoing. Existing detection methods perform effectively with all available data; however, in the early stage of a phishing scam, the performance is not satisfactory. This paper proposes the Early-stage Phishing Detection framework, which contains data processing, feature extraction, and detection components. One main contribution of this paper is the design of features based on the local graph structure and time-series attributes of the transaction network. Moreover, the phishing scam is divided into early, middle, and late stages, according to the fraud amount. Finally, the proposed method is validated on a real dataset, and the experimental results show that it can achieve the best performance. Specifically, in the early stage, the proposed method performs far better than the embedding methods. In addition, with time, it can maintain a certain degree of robustness. Thus, this paper provides useful ideas for regulators and platforms to detect phishing scams in advance.
On the (non)scalability of target media used in controlled archaeological projectile experiments
Authors: Pettigrew Devin B. , Bamforth Douglas B.
Published: June 2022

When they work, controlled experiments can efficiently and clearly reveal essential characteristics of the functions and performance of ancient hunting and fighting weapons. However, homogenous target media must be carefully validated to ensure that the same variables that made weapons effective in their original application are being captured in controlled tests. Although homogenous flesh simulants have proven effective for studying firearms, the same simulants cannot be assumed to be effective when testing low velocity piercing/cutting projectiles. In fact, we build on past research showing that two flesh simulants that are commonly used by archaeologists, ballistics gelatin and pottery clay, fail to capture how atlatl darts and arrows perform when penetrating living bodies. In accord with forensic research of knife stabbing attacks, polymeric skin simulants may prove effective in future experiments, but this requires further research.
The Swiss Health Insurance Literacy Measure (HILM-CH): Measurement Properties and Cross-Cultural Validation
Authors: Bardy Tess L. C.
Published: June 2022

Background
Most consumers face difficulties when choosing and navigating health insurance plans. Health insurance literacy (HIL) has been discussed as a critical lever to ensure efficient choices and navigation in choice-based health insurance systems. Still, existing evidence about HIL mainly comes from the US, and the only validated scale, the Health Insurance Literacy Measure (HILM), may not be adequate to measure HIL outside US samples. This paper describes the measurement properties of the Swiss Health Insurance Literacy Measure (HILM-CH), the first scale to measure HIL in Switzerland.
Methods
The items of the HILM-CH were adapted from the HILM in German, French, and Italian. A panel of experts refined it to ensure its suitability for the Swiss context. The final version of the HILM-CH contains 21 items, and other relevant measures were administered in the Swiss Health Insurance Literacy Survey to a sample of 6036 insurees. Measurement properties were investigated overall and per linguistic group. Internal reliability was determined using Cronbach’s alphas. Criterion validity was examined through convergent and concurrent validity of the HILM-CH. The construct validity was assessed using factor analysis. Measurement invariance of the HILM-CH between linguistic regions was further evaluated using multiple-group confirmatory factor analyses.
Results
The HILM-CH had acceptable to good reliability (alphas between 0.70 and 0.91). Concurrent and convergent validity showed that HILM-CH is a good measurement of HIL. Factor analysis revealed a four-factor model and showed a good fit to the data (CFI = 0.977; TLI = 0.974; RMSEA = 0.061; SRMR = 0.032). Using the established four-factor model, measurement invariance was established across Switzerland’s German, French, and Italian-speaking regions.
Conclusions
The HILM-CH is a reliable and valid measure of HIL across Switzerland’s German, French, and Italian-speaking regions. It can be used in future research to find associations between HIL and individual characteristics.
Splay-bend nematic phases of bent colloidal silica rods induced by polydispersity
Authors: Kotni Ramakrishna , Grau-Carbonell Albert , Chiappini Massimiliano , Dijkstra Marjolein , Blaaderen Alfons van
Published: June 2022

Liquid crystal (LC) phases are in between solids and liquids with properties of both. Nematic LCs composed of rod-like molecules or particles exhibit long-range orientational order, yielding characteristic birefringence, but they lack positional order, allowing them to flow like a liquid. This combination of properties as well as their sensitivity to external fields make nematic LCs fundamental for optical applications e.g. liquid crystal displays (LCDs). When rod-like particles become bent, spontaneous bend deformations arise in the LC, leading to geometric frustration which can be resolved by complementary twist or splay deformations forming intriguing twist-bend (NTB) and splay-bend (NSB) nematic phases. Here, we show experimentally that the elusive NSB phases can be stabilised in systems of polydisperse micron-sized bent silica rods. Our results open avenues for the realization of NTB and NSB phases of colloidal and molecular LCs.
Mechanism Study on the Spatial Distribution Pattern and Vertical Migration of Phosphorus in a Constructed Wetland
Authors: Tian Yonglan , Chen Hao , Yang Liuye , Zhang Huayong , Tian Wang , Wang Zhongyu , Huang Tousheng , Lv Wei , Zhong Xin
Published: June 2022

In this work, phosphorus fractionations (PFs) in the surface, overlying and interstitial water, sediments and two macrophytes (reed and cattail) were investigated in a near-nature constructed wetland. The mechanism of vertical migration and transformation, diffusion flux of sediment and overlying water and the risk of phosphorus release from sediments were studied. The results showed that the occurrence of macrophytes influenced the horizontal and vertical distributions of phosphorus. Reed community area resulted in different orders of TP, TDP and SRP concentrations in the surface, overlying and interstitial water as well as higher removal efficiencies than open water area and cattail community area. Phosphorus distributions in reed community area were closely correlated to the environmental factors and phosphorus in the overlying water were significantly correlated to the biomass and morphological characteristics of reeds (p < 0.01). TP in sediments were positively correlated to the OM contents in both macrophytes free and covered area (p < 0.05) and Org-P was negatively correlated to APA in both open water area (p < 0.05) and reed community area (p < 0.01). Phosphorus diffused from sediment into overlying water due to the positive diffusion flux of sediment-overlying water. The degree of phosphorus saturation (DPS) in macrophytes covered area communities was higher while the phosphorus sorption index (PSI) was lower than that in macrophytes free area. The eutrophication risk index (ERI) of wetland sediment showed the risk of phosphorus released from sediment was high, especially in cattail community area. The results of this study provided references for macrophytes management and removal efficiency improvement in constructed wetlands.
Meta Reinforcement Learning Based Computation Offloading Strategy for Vehicular Networks
Authors: Yang chao , Gao Yangshui , Ding Hongwei , Nie Rencan , Li Bo
Published: June 2022

Deep learning (DL) and reinforcement learning (RL) based methods can efficiently generate offloading strategies for computational offloading problems in mobile edge computing (MEC) environments. However, the rapid movement of vehicles in the vehicular network causes dynamic changes in the network environment, and DL or RL methods require additional training samples and multiple gradient updates before the model converges, which is time-consuming. In this letter, we propose a meta reinforcement learning-based computation task offloading and resource allocation (MRLOA) algorithm for vehicular networks. Specifically, the MRLOA can converge quickly for a new task with a small number of experience and gradient updates based on a pre-trained meta policy. Simulation results show that our proposed algorithm can more quickly adapt to new computational offloading tasks in the vehicular network environment compared to traditional baseline algorithms.
Bacterial degradation of bisphenol A and its analogues: An overview
Authors: Farias Julia de Morais , Krepsky Natascha
Published: June 2022

Bisphenol A (BPA) is one of the most produced synthetic monomers in the world and is widespread in the environment. Due to its adverse effects on life, BPA was replaced by bisphenol analogues (BP). Bacteria can degrade BPA and other bisphenol analogues (BP) diminishing their concentrations in the environment. To summarize the knowledge and contribute to future studies, in this review we surveyed papers on bacterial degradation of twelve different bisphenol analogues published until 2020. A total of 84 original papers from PubMed and Google Scholar were selected for this review. Most of the studies (95.2%, n = 80) on bacterial degradation of bisphenol analogues (BP) focused on bisphenol A (BPA), and then on BPF, and BPS. The number of studies on bacterial degradation of bisphenol analogues increased almost six times from 2000 (n = 2) to 2020 (n = 11). Indigenous microorganisms and the genera Sphingobium and Cupriavidus could degrade several BP. However, few studies focused on Cupriavidus. Biodegradation of BPA does not imply the degradation of other analogues. The acknowledgement of various aspects of BP bacterial biodegradation is vital for choosing the most suitable microorganisms for the bioremediation of a single BP or a mixture of BP.
Investigations on Deformation Characteristics of AZ31B Magnesium Alloys during Friction Heating Incremental Sheet Forming
Authors: Li Panpan , Zhou Liuru , Jiang Xu , Wang Jiahao , Hu Shiyao , Yang Qunyi
Published: June 2022

A method of friction heating incremental sheet forming (FHISF) is presented with friction heating of rotating tools and sheet metal, which does not necessitate the use of external heating and saves costs. Utilizing orthogonal experimental design, CATIA reverse engineering methods and finite element model (FEM) analysis, the deformation characteristics of AZ31B magnesium alloy FHISF are investigations, which include formability, geometrical accuracy, thickness distribution, Mises stress and plastic strain at various forming stages. The findings reveal that: In FHISF, increasing the spindle speed is the most significant method to improve the formability, and the maximum forming angle is similar to that of other heating-assisted incremental sheet forming can reach 71°. The bending phenomenon appears early in the forming process, causing the upper corner area to have the poorest precision, and the lower corner area to have visible flaws. The actual part sidewall stabilization region is 11% thinner than the theoretically stable thickness. By the establishment of the FEM, observed and predicted the thickness and stress-strain changing trend of the complete FHISF process satisfactorily.
WITHDRAWN: Evaluation of the Effect of Headgear on the Eruption of Maxillary Third Molars: A Longitudinal Controlled Study.
Authors: Ghoneim Salma H , Alsolami Aseel M , Alshamrani Samer S , Nassar Afnan A , Alansari Reem A , Linjawi Amal I
Published: June 2022

Objectives: To evaluate the short and long term effects of headgear on the third molar eruption space and the eruption status of the maxillary third molar at the long term follow up. Materials and Methods: Records were collected for 33 Class II cases treated with headgear. Three records were collected: before treatment (T1), after treatment (T2), and at the long term follow up (T3). Three corresponding time points were selected for the control sample. Lateral cephalograms were used to measure the distance from the distal surface of the maxillary first molar to pterygoid vertical (PTV). The third molar status at T3 was categorized into five groups as follows: impacted, extracted, erupted, missing, and formation stage. Results: No significant statistical difference was found between test and control groups for U6-PTV at T1 (p= 0.128) and T3 (p= 0.289). However, a significant statistical difference was found at the end of treatment T2 (p=0.000). Regarding molar status, no significant statistical difference was observed (p= 0.108). Conclusion: Headgear caused a temporary decrease in the U6-PTV distance that was recovered later on. This decrease was not observed in the control group and did not affect the eruption of the third molar. Clinical Relevance: The use of headgear to correct Class II malocclusion does not seem to increase the risk of upper third molar impaction.
From pilot site knowledge via integrated reservoir characterization to utilization perspectives of a deep geothermal reservoir: 3D geological model at the research platform Groß Schönebeck in the Northeast German Basin
Authors: Norden Ben , Bauer Klaus , Krawczyk Charlotte M.
Published: June 2022

The Groß Schönebeck site in the North German Basin serves as research platform for studying the geothermal potential of deeply buried Permian reservoir rocks and the technical feasibility to extract their geothermal heat. The structural setting of the site was investigated in more detail by studying a newly acquired 3D-seismic survey to improve the structural picture that was based on several old 2D seismic lines so far. The new data allows a revision of the geological interpretation of the site, enabling the set-up of a new reservoir model and providing base information for a possible further site development of the Permian and Permo-Carboniferous targets. The 3D seismic of Groß Schönebeck allows for the first time a consistent geological interpretation and model parameterization of the well-studied geothermal site. Main reflector horizons and the corresponding stratigraphic units were mapped and the structural pattern of the subsurface presented in the 8 km x 8 km x 4 km large seismic volume. While some fracture and fault patterns are visible in the upper Zechstein and post-Permian units, formerly hypothesized large offset faults are not present in the Rotliegend reservoir itself. However, a well-established graben-like structure at the top of the Zechstein succession is most likely related to broken anhydritic Zechstein stringers. Most reflectors above the salt show a rather undisturbed pattern. The main reservoir sandstone of the Dethlingen Formation (Rotliegend) was mapped and characterized. The base of the underlying Permo-Carboniferous volcanic rock sequence and hence its thickness could not be depicted reliably from the geophysical data. Based on the new seismic data and the available reconnaissance drilling, logging, and laboratory data of the Groß Schönebeck research site, the thickness and distribution of the sedimentary Rotliegend (with emphasis of the sandy reservoir section) and of the volcanic rock sequence was modelled and parameterized with petrophysical properties (i.e., total and effective porosity, fluid permeability, bulk density, thermal conductivity, thermal diffusivity, and specific heat capacity), providing a more realistic reservoir description. The data and interpretation constitute the basis for a better understanding of the dominating processes at the site and for future measures. Further site development could include a deepening of one well to give evidence on the volcanic rock sequence and consider deviated wells into favourable zones and the design of a fracture-dominated utilization approach.
WITHDRAWN: Drawing-upsetting-extrusion-clinching of high strength steel and aluminum alloy
Authors: Luo Lingfeng , Huang Shangyu , Mei Yang , Hu Jianhua , Ou Bing
Published: June 2022

To realize good point connection between high-strength steel and aluminum alloy, a process of drawing-upsetting-extrusion-clinching was proposed. First, the sheets were thinning drawn, then the bottom of the protrusion part was extruded, forming the necessary initial interlock, finally the protrusion part was reverse press clinched, forming a certain height of the clinched head. Taking DP980 high strength steel and Al5083 aluminum alloy as the connection objects, using the method of numerical simulation combined with experimental test, the mold was made and the experiment was carried out on the basis of numerical simulation. The experimental results proved the feasibility of the process and the effectiveness of the numerical model. The simulation and experimental results show that the necessary interlock in the drawing-upsetting-extrusion stage is the premise of effective connection. The relative protrusion height should be around 55.6% after reverse-press-clinching. The best comprehensive mechanical properties measured by strength test were shear resistance of 2644N, fatigue life of 24535 times and peel resistance of 1522N. Through failure form analysis, the relationship between the interlock Tu and the neck thickness Tn of the joint with the best comprehensive mechanical properties was established: Tu = 0.35Tn. The design method of die and process parameters when the sheet thickness changes was researched by numerical simulation. The results show that the clearance between the punch and die, bottom thickness are directly proportional to the sheet thickness, and the drawing depth is directly proportional to the punch radius.
Quantitative Investigation on Localized Deformation Process of Rocks by Uniaxial Test and Digital Image Correlation
Authors: Zhu Ling , Cui Shenghua , Pei Xiangjun , Luo Luguang , Cheng Jianlong , Wang Hui , Du Ruifeng , Yang Qingwen
Published: June 2022

The uniaxial monotonic and cyclic loading tests were carried out. The acoustic emission (AE) events and surface deformation images in the loading process were obtained using the AE system and digital image correlation (DIC). The variance of the deformation field was introduced to reveal the formation and evolution processes of the localized deformation. The results show that the variance begins to increase significantly in the initiation of the macro-scale failure stage, and it increases sharply under cyclic loading before failure. The shape of the stress-variance hysteresis curve varies with increasing upper limit stress, and four types of stress-variance hysteresis curves were revealed. The damage variables are respectively defined by cumulative AE counts and variance, and the evolution process of damage variable can be divided into crack closure stage, initial damage stage, stable development stage, accelerated development stage and failure stage. By proposing the differentiation rate, it is found that there are apparent failure precursor points under monotonic and cyclic loading.
Detection of chlorfenapyr resistance in the malaria vector Anopheles gambiae contrasts with full susceptibility in Anopheles funestus across Africa
Authors: Tchouakui Magellan , Assatse Tatiane , Tazokong Hervé R. , Oruni Ambrose , Menze Benjamin D. , Nguiffo-Nguete Daniel , Mugenzi Leon M. J. , Kayondo Jonathan , Watsenga Francis , Mzilahowa Themba , Osae Michael , Wondji Charles S.
Published: June 2022

New insecticides have recently been produced to help control pyrethroid-resistant malaria vectors including the pyrrole chlorfenapyr. Monitoring the susceptibility of mosquito populations against novel insecticides and potential cross-resistance with current insecticides is vital for better resistance management. In this study, we assessed the resistance status of the major malaria vectors Anopheles gambiae and Anopheles funestus to chlorfenapyr across Africa and explored potential cross-resistance with known pyrethroid resistance markers.Efficacy of chlorfenapyr 100µg/ml against An. gambiae and An. funestus from five Cameroonian locations, the Democratic Republic of Congo, Ghana, Uganda, and Malawi was assessed using CDC bottle assays. Synergist assays were performed with PBO (4%), DEM (8%) and DEF (0.25% and several pyrethroid-resistant markers were genotyped in both species to assess potential cross-resistance between pyrethroids and chlorfenapyr.Resistance to chlorfenapyr was detected in An. gambiae populations from DRC (Kinshasa) (mortality rate: 64.3 ± 7.1%) Ghana (Obuasi)(65.9 ± 7.4%), Cameroon (Mangoum ;75.2±7.7% and Nkolondom ; 86.1 ± 7.4). In contrast, all An. funestus populations were fully susceptible. A negative association was observed between the L1014F-kdr mutation and chlorfenapyr resistance with a greater frequency of homozygote resistant mosquitoes among the dead mosquitoes after exposure compared to alive (OR=0.5; P=0.02). No association was found between GSTe2 (I114T in An. gambiae; L119F in An. funestus) and resistance to chlorfenapyr. A significant increase of mortality to chlorfenapyr 10µg/ml was observed in An funestus after to PBO, DEM and DEF whereas decreased mortality was observed in An gambiae after pre-exposure to PBO although not significant.This study reveals a greater risk of chlorfenapyr resistance in An. gambiae populations than in An. funestus. However, the higher susceptibility in kdr-resistant mosquitoes points to the efficacy of chlorfenapyr against the widespread kdr-based pyrethroid resistance.
A novel initial wiring technique for chronic total occlusion of the superficial femoral artery using the structural features of a polymer jacket guidewire
Authors: Karashima Eiji , Soga Yoshimitsu , Arima Takeshi , Noda Hirotaka , Yasuda Shioto , Kaneko Takeo
Published: June 2022

Background: To evaluate the efficacy of the GLadIus MG drilLINg technique (GLIMGLIN), a novel initial wiring technique using the Gladius MGTM structural features, for crossing the superficial femoral artery (SFA) with chronic total occlusion (CTO). Methods: This retrospective, single-center study enrolled 27 symptomatic patients (mean age 77.4±8.5 years; 20 men) with de novo SFA CTO (mean CTO length 16.1±8.9 cm) who underwent GLIMGLIN as the initial wiring between January 2020 and December 2021. The success of GLIMGLIN was defined when the wire crossing was completed using a Gladius MGTM and a microcatheter without any additional devices. GLIMGLIN was defined as one of the conventional wiring techniques.Results: The success rates of GLIMGLIN and conventional wiring were 48.1% and 74.1%, respectively. Intravascular ultrasound findings showed complete true lumen passage in the GLIMGLIN success group. Compared to the failure group, the proximal (6.3±0.8 vs. 5.5±0.9 mm, p=0.02) and distal (5.9±0.5 vs. 5.4±0.6 mm, p=0.02) reference vessel diameters were significantly larger, and the rate of calcium angle >180° was significantly fewer (30.8 vs. 71.4 %, p=0.04) in the success group. No significant difference was shown in the CTO length between the group. Total wiring time, total procedure time, and fluoroscopic time were significantly shorter in the success group. Conclusions: GLIMGLIN may enable operators to perform CTO wiring easily, efficiently, and at a lower cost in selected cases.
Annealing effect of thermotropic liquid crystalline copolyester fibers on thermo- mechanical properties and morphology
Authors: Park Sanghyeon , Na Yeji , Kim A Young , Kwac Lee Ku , Kim Hong Gun , Chang Jin-Hae
Published: June 2022

A series of thermotropic liquid crystal copolyesters (Co-TLCPs) was prepared by melt polymerization using 2,5-diethoxyterephthalic acid (DTA), 2,7-dihydroxynaphthalene (DHN), and p-hydroxybenzoic acid (HBA) monomers, where the HBA content was varied (0–5 mol). At 3 mol HBA, the Co-TLCPs formed nematic mesophases, while below this concentration, the liquid crystalline phase did not appear. The Co-TLCP sample with 3 mol HBA was subjected to melt spinning and heat-treated under various conditions (temperature and time) to investigate their effect on the thermo-mechanical properties and degree of crystallinity. The objective was to determine the critical heat treatment condition that can maximize the properties of the spun Co-TLCP fibers. The microstructure of the heat-treated fiber was investigated using scanning electron microscopy, and the optimal annealing conditions were confirmed based on the morphology of the fiber, which exhibited a skin–core structure owing to the varying heat and pressure conditions applied during spinning.
Genetic labeling reveals cellular expression pattern of neuregulin 1 in mouse forebrain
Authors: Ding Chen-Yun , Ding Yan-Ting , Wang Yao-Yi , Ji Haifeng , Yin Dong-Min , Zhang Xinwen
Published: June 2022

Neuregulin 1 (Nrg1) encodes a neurotrophic factor and is genetically associated with schizophrenia, bipolar disorder and major depression. NRG1 has been shown to play important roles in neurodevelopment and neurotransmission. However, the knowledge about the cellular expression pattern of Nrg1 in mouse forebrain remains controversial and inconclusive. Here we used CRISPR/Cas9 techniques to generate Nrg1Cre/+ knockin mice which express the Cre recombinase immediately before the stop codon of Nrg1 gene. By crossing the Nrg1Cre/+ mice with Ai14 reporter mice which express fluorescent protein tdTomato in a Cre-dependent manner, we generated Nrg1 reporter mice which express tdTomato in cells where Nrg1 gene is actively transcribed. Using fluorescence imaging and unbiased stereology, we revealed the cellular expression pattern of Nrg1 in mouse forebrain regions including the olfactory bulb, cerebral cortex, striatum and hippocampus. We further performed stereotaxic injection of adeno-associated virus (AAV) which express tdTomato in a Cre-dependent way into different forebrain regions of adult Nrg1Cre/+ mice, and thus explored the distribution and axon projection of Nrg1-positive cells. These results provide fundamental information needed for the study of Nrg1 function in mouse forebrain. Moreover, the Nrg1Cre/+ mice generated here may represent a useful tool to study the function of neuronal populations expressing Nrg1.
Development of Cellulose Aerogel as a New Material for the Reduction of Harmful Substances in Cigarette Smoke
Authors: Rahamin Hashem , Jonoobi Mehdi , Abzan Nooshin , Sepahvand Sima , Ashori Alireza , Mekonnen Tizazu H
Published: June 2022

The current study proposed a novel and improved cigarette filtration design comprising cellulose nanofibers (CNF) and powdered activated carbons (PAC) with different dry matter contents. The proposed filter samples were primarily analyzed to verify their applicability as a cigarette filter via several measurements and standard tests, such as SEM, BET, DSC, and airflow permeability analysis and obtained results were compared with cellulose acetate (CA) sample which is used as a conventional filter in cigarettes. The preliminary results indicated noticeable improvement compared to the reference CA. Also, The cigarettes were tested using a smoking machine and the filtered smoke was analyzed using GC-MS to evaluate the performances of the filters in reducing the main harmful substances present in smoke. The obtained result showed that the filters made of CNF and PAC significantly reduced the hurmful substances in comparison with reference but do not significantly affect the nicotine and therefore will not negatively impact the trance level of smokers.
Enhanced Sensitivity of Surface Plasmon Resonance Biosensor for the Selective Detection of Immunoglobin (IgG)
Authors: Kumar Awadhesh , Dubey Sarvesh K. , Kumar Anil , Tripathi Chandra Shekhar Pati , Srivas S. K.
Published: June 2022

In this work, we propose a surface plasmon resonance (SPR) biosensor based on a hybrid structure of silicon nitride (Si3N4), molybdenum trioxide (MoO3), and graphene oxide (GO) in the Kretschmann configuration. In order to investigate the performance parameter of the SPR biosensor, we calculate, theoretically, the reflectance spectra of the proposed model and analysed it. The investigation of various performance parameters i.e., sensitivity, detection accuracy, and quality factor, of sensor configuration are theoretically done with the optimized thickness of silver (55 nm), silicon nitride (5 nm), molybdenum trioxide (10 nm), and graphene oxide (2.55 nm) respectively. The sensitivity, detection accuracy, and figure of merit for the proposed SPR structure is found at 301 deg./RIU, 4.01, and 133 RIU-1 respectively for the detection of IgG. It is clearly observed that the sensitivity of the proposed biosensor is enhanced by 43.2% with respect to other conventional SPR biosensors. The refractive index of the analyte changes from 1.33 to 1.37 due to adsorption of the analyte at the GO surface. The proposed sensor design is able to detect the small change in the refractive index of the sensing media doped with the analyte. Therefore, the proposed structure of the SPR sensor may have potential applications in the field of biomedical and chemical sensing applications.
Forest fire at the K-Pg boundary on the Pacific margin of Baja California, Mexico: timing and causes
Authors: Catharina Amanda Santa , Kneller Benjamin , Marques Juliana , McArthur Adam , Cevallos-Ferriz Sergio , Theurer Thomas , Kane Ian , Muirhead David
Published: June 2022

We report K-Pg-age deposits in Baja California, Mexico, consisting of terrestrial and shallow marine materials re-sedimented onto the continental slope, including corals, gastropods, bivalves, shocked quartz grains, an andesitic tuff with a SHRIMP U-Pb age (66.12 ± 0.65 Ma) indistinguishable from that of the K-Pg boundary, and charred tree trunks. The overlying mudstones show an iridium anomaly, and fungal and fern spores spikes. We interpret these heterogeneous deposits as a direct result of the Chicxulub impact, and a mega-tsunami in response to seismically-induced landsliding. The tsunami backwash carried the megaflora offshore in high-density flows, remobilizing shallow marine fauna and sediment en route. Charring of the trees at temperatures up to >1000°C took place in the interval between impact and arrival of the tsunami, which on the basis of seismic velocities and historic analogues amounted to only tens of minutes at most. This constrains the timing and causes of fires, and the minimum distance from the impact site over which fires may be ignited.
A lack of a definite correlation between male infertility and single nucleotide polymorphisms in sperm mitochondrial genes MT-CO3, MT-ATP6 and MT-ATP8
Authors: Jaweesh Mayyas saleh , Hammadeh Mohamad Eid , Dahadhah Fatina W. , Smadi Mohammad A. Al , Zoubi Mazhar Salim Al , Alarjah Manal Issam Abu , Amor Houda
Published: June 2022

An inability of a man to conceive in a potentially fertile woman is defined as male infertility. It is reported that 30–40% of males in their reproductive years have abnormalities in sperm production, either qualitatively or quantitatively, or both. However, genetic factors result in up to 15% of male infertility cases. The present study aimed to analyze the possible correlations between infertility and polymorphisms in sperm mitochondrial CO3, ATP6 and ATP8 genes in subfertile men. For 67 subfertile and 44 fertile male samples, Sanger sequencing of selected mitochondrial DNA genes was done. A total of twelve SNPs in the MT-CO3 gene: rs2248727, rs7520428, rs3134801, rs9743, rs28358272, rs2853824, rs2856985, rs2854139, rs41347846, rs28380140, rs3902407, and 28411821, fourteen SNPs in the MT-ATP6: rs2001031, rs2000975, rs2298011, rs7520428, rs9645429, rs112660509, rs6650105, rs6594033, rs6594034, rs6594035, rs3020563, rs28358887, rs2096044, and rs9283154, and ten SNPs in the MT-ATP8: rs9285835, rs9285836, rs9283154, rs8179289, rs121434446, rs1116906, rs2153588, rs1116905, rs1116907, and rs3020563 were detected in the case and control groups at different nucleotide positions. Only the rs7520428 in the MT-CO3 and MT-ATP6 showed a statistically significant difference between subfertile and fertile groups in the genotype’s and allele’s frequency test (P < 0.0001 for both). The results of our study suggest that male infertility is linked with rs7520428 SNP in MT-CO3 and MT-ATP6. The studied polymorphic variations in the MT-ATP8 gene, on the contrary, did not reveal any significant association with male infertility
Design of a Compact Tri-band Mimo Antenna With Reduced Mutual Coupling
Authors: rao srinivasa , Babu K. Jagadeesh , Prasad A. Mallikarjuna
Published: June 2022

The mutual coupling analysis in a tri-band MIMO antenna is the subject of this article. The suggested antenna has three frequencies of resonance: 5.8 GHz, 7.2 GHz, and 8.6 GHz. This mutual coupling study is performed in three ways: (1) without the use of any additional structure; (2) with the use of additional structure (2) Polarization diversity (3) Spatial diversity The mutual coupling is negated in the first technique because the current flow in adjacent arms is in the opposite direction. The second method involves altering the distance between them to do mutual coupling analysis. In the third method, mutual coupling analysis is performed for various antenna orientations. Finally, all three approaches are compared in terms of mutual coupling. The MIMO antenna's performance was further tested in terms of radiation pattern, ECC, gain, and efficiency. It's also worth noting that the simulation results match the measured ones.
Surgical management of traumatic spinal injuries in Sylvanus Olympio Teaching Hospital
Authors: Doléagbénou Agbéko Komlan , Djoubairou Ben Ousmanou , Ahanogbé Mensah Kodjo Hobli , Egu Komi , Békéti Anthony Katanga , Kpélao Essossimna , Abalo Anani
Published: June 2022

Introduction : Traumatic spinal injuries (TSI) is a global disease burden in low - and middle–income countries (LMIC). The burden of TSI is higher in LMICs than in developed countries. Despite improvements in TSI management, resource-constrained settings have not benefitted from this progress to the same extent as more developed countries. Hypothese : Spinal implants availability and early surgery are associated with improved neurologic function.Material and methods: This is a retrospective and descriptive study from November 2017 to October 2020. We included adult patients who presented with traumatic spine injury and who underwent surgery stabilization.Results: A total of 93 patients were studied. The population was young (35.92 ± 9.68 years old), men (91.4%). Road traffic accidents accounted for 85% of patients. At presentation, 59.1% of patients had an incomplete neurologic deficit (ASIA B-D). The cervical spine was the most common segment injured (57%). The median time from admission to the operating room was 21.06 ± 11.8 days. After surgery, 15.3% improved by at least 1 ASIA grade. Bedsores (14%) and superficial wound infection (10.8%) were the most typical complications in our series after surgery. Discussion : According to the AANS/CNS guideline, available literature has defined « early » surgery inconsistently, ranging from < 8 hours to < 72 hours. In our series, the median time from admission to the operating room was 21.06 ± 11.8 days (range 2-62). That finding could be explained by the fact that most low-income people have to pay out of their pocket because the rate of medical insurance coverage is low. In the study, only 17.2% of patients have public insurance, and 2.2% private insurance. We performed three types of surgery: anterior cervical discectomy and fusion, anterior cervical corporectomy with tricortical iliac crest graft and plate, and posterolateral thoracic/lumbar fusion. Implant availability for posterior cervical fusion was the principal driver of that decision in our limited resources.Type of study and level of proff: level 3, retrospective cohort study.
Supporting post-pandemic recovery: Capabilities, opportunities, and motivations of practitioners to deliver oral health promotion and behaviour change conversations to parents of young children in community settings.
Authors: Goldthorpe Joanna , Killbee Lauren , Pretty Iain , Cotterill Sarah , Hart Jo , Peters Sarah
Published: June 2022

The COVID-19 pandemic exacerbated vulnerabilities and inequalities in children’s oral health and treatment activity virtually ceased during periods of lockdown. However, opportunities to support the dental workforce through offering some preventative care in outreach settings may exist. This has the additional benefit of potentially reaching children who do not routinely see a dentist. The aim of this study was therefore to investigate views around upskilling practitioners working in strategic community settings to support families of pre-school aged children to adopt and maintain preventative oral health behaviours. Using the Capability, Opportunity and Motivation model of behaviour (COM-B) to structure our research, we conducted semi-structured interviews with 16 practitioners (dental and non-dental) and analysed the data using deductive framework analysis. The data was a good fit with the COM-B model and further themes were developed within each construct, representing insights from the data. Early years practitioners can reach vulnerable children who are not usually brought to see a dentist. Staff have the capability, opportunity and motivation to support the oral health behaviours of families. Further research is needed to identify training needs, acceptability to parents, and supporting dental practice teams to work in partnership with early years settings. In brief: · Preventative dental activity was greatly diminished during the COVID-19 pandemic however there may be opportunities for professionals based outside general dental practice to have oral health behaviour change conversations with parents· Early years practitioners in particular can potentially reach vulnerable children who are not routinely brought to dental check-ups and have the capability, opportunity and motivation to have oral health behaviour change conversations with parents.· Further research is needed to identify training requirements and how to develop supportive relationships with NHS dental teams
A numerical study of Two-Dimensional Magnetized Bioconvective Unsteady fluid flow in two Stretching Parallel Plates with Internal Heating and Chemical Reaction Effects
Authors: Khan Waris , Rasheed Haroon
Published: June 2022

Driven by scientific development, the bio-convection unsteady nanofluid flow has gained enormous attention in research due to its applications in various disciplines such as biosensors, biological polymer synthesis, pharmaceutics, microbial improved oil recovery, and environment-friendly applications. As such, this study aims to investigate the mixed bio-convective magnetized and electrically conducting 2-dimensional flow in view of two extended wall channels subjected to MHD, thermal radiation, and binary chemical reaction effects. A mathematical framework is developed underflow of a nonofluid based on certain conditions. The implication of Soret and Dufour impacts is considered in the model problem. Such a nonlinear mathematical model is tackled by invoking similarity solutions for mass conservation, momentum, temperature, concentration, and micro-organisms expressions. The dimensionless principles (ODEs) are addressed by the efficacy Nactsheim-Swigert shooting along with the iteration process, explicitly through shooting technique (RK-4). The outlines of distinguished emerging constraints on flow fields are offered through the plotted graphic visuals. The impact of physical quantities of engineering interest is offered numerically via tabulated values.
Associations of morbid obesity with late diagnosis of gestational diabetes, and with related obstetrical and neonatal outcomes
Authors: Shqara Raneen Abu , Or Shany , Francis Yara Nakhleh , Weiner Yifat , Lowenstein Lior , Wolf Maya Frank
Published: June 2022

Objective: To investigate associations of maternal obesity with late GDM diagnosis (>34 weeks) and related obstetrical and neonatal outcomes.Study Design: This was a retrospective cohort study of 238 women who underwent late oral glucose tolerance tests (OGTT) (>34 weeks) for suspected macrosomia or polyhydramnios. Obstetrical and perinatal outcomes were stratified by GDM and morbid obesity (BMI>35 kg/m2) status. Obstetrical complications included pre-eclampsia, induction of labor, cesarean delivery, shoulder dystocia, and third or fourth-degree perineal tear. Neonatal outcomes included Apgar score, arterial cord pH, neonatal hypoglycemia, jaundice, the need for phototherapy, and polycythemia. Results: Late GDM rate was 22.2% and increased the risk for macrosomia, large-for-gestational-age fetus, induction of labor; and neonatal hypoglycemia, jaundice, and need for phototherapy. Conclusion: Adverse pregnancy outcomes are related to morbid obesity in women with late GDM; this population requires special surveillance. Repeat GDM screening beyond 34 weeks should be considered.