bluuebunny/crossref_metadata_2025 huggingface dataset:
Doppler espectral del flujo de las venas hepáticas en el perro
Authors: Bartolomeo Mario
Published: December 2024

En condiciones normales, el flujo venoso hepático drena en la vena cava caudal y ésta en el atrio derecho. Esto ocurre durante la sístole ventricular gracias a la caída de la presión atrial derecha, en respuesta a la relajación atrial y al desplazamiento ventral del anillo tricúspide.
El registro Doppler normal del flujo de las venas hepáticas en el perro muestra una morfología caracterizada por tres ondas. Una onda sistólica negativa (S) que se produce en la sístole ventricular por el descenso del anillo tricúspide y la relajación del atrio derecho; una onda diastólica negativa (D) producida por el llenado ventricular rápido y una onda positiva (A) generada por la sístole atrial. El objetivo del presente estudio fue establecer la velocidad pico de cada una de las ondas del flujo de las venas hepáticas en el perro. Se estudiaron 30 caninos cardiológicamente sanos. Se utilizó un equipo SonoSite con transductor electrónico multifrecuencia de 6,5 a 5 MHz.  El Doppler pulsado se configuró estableciendo el límite de Nyquist en 50 – 60  cm/seg y un filtro de pared de 100 Hz .Para obtener mediciones exactas de frecuencia y velocidad se trabajó con un ángulo  Doppler  menor a 60 °. Los resultados obtenidos fueron los siguientes: Onda (S ): Media :31,60; Desvío estándar (D.E.): 7,53; Onda (D) Media: 20,70; Desvío estándar (D.E):; Onda (A): Media :22,30 , Desvío estándar (D.E): 2,26. La aplicación clínica de este método es ideal para pacientes con patología tricúspide. Ya que en la regurgitación tricúspide severa, a diferencia del flujo normal, la eyección ventricular derecha genera un flujo reverso sostenido que alcanza a través del atrio derecho el sistema de la vena cava y venas hepáticas Produciendo así un flujo reverso sistólico registrado en las venas hepáticas como onda S positiva, siendo ésta en condiciones normales negativa. En presencia de regurgitación tricúspide moderada la onda S (sistólica) se halla disminuida o ausente.
Estudo da metodologia do processamento da pele de tilápia para tratamento de queimaduras
Authors: Reis Maycon do Amaral , Marigo Ingrid Melo Rodrigues , Rego Ramon de Sousa , Rodrigues Filho Jandyr de Almeida , Souza Hingrid Barbosa de
Published: December 2024

A incidência de queimaduras é o quarto tipo de trauma que mais acontece no mundo, podendo ser lesões de primeiro, segundo ou terceiro grau. Abordando os dados disponibilizados pela OMS (Organização mundial de saúde), ela descreve como uma das principais causas da letalidade dos pacientes que sofreram queimaduras as infecções sistêmicas. Para essa problemática existem diversas tecnologias disponíveis para tratamento, destacamos neste trabalho a utilização do couro de tilápia como método de tratamento. Objetivou-se descrever a prática no processamento da pele de tilápias e testar diferentes métodos de processamento e esterilização, para isso foram realizadas variações do período de imersão do bioproduto em glicerol e testando a eficiência da esterilização com diferentes tratamentos e a inclusão de uma etapa em câmara de ozônio, garantindo que o bioproduto não seja degradado.  Entre os tratamentos avaliados concluímos que a inclusão da etapa com ozônio foi favorável para a garantia da esterilidade. Obtivemos um resultado satisfatório, constatando a esterilidade da pele de Tilápia
Inovação na 1ª série do ensino médio: separação de misturas e compostos emergentes na água tratada como temática de aprofundamento no itinerário formativo de ciências da natureza
Authors: Silva Márcio Eustáquio Pereira da , Santos Carolina Rodrigues , Rocha Ana Beber e Souza Fiorilo , Silveira Ana Clara Oliveira Beltrão , Domingueti Lavínia , Leão Letícia Mendes
Published: December 2024

O presente trabalho apresenta a proposta de material didático com a temática de separação de misturas e compostos emergentes na água tratada como aprofundamento em Itinerário Formativo de Medicina, Saúde e Biológicas para o Ensino Médio. A aplicação deste material didático permitiu que 4 alunas, com bom desempenho acadêmico em 2024, pudessem participar como coautoras deste trabalho, o que favoreceu aspectos de melhoria no processo de ensino/aprendizado e no entendimento relacionado à produção de uma publicação científica. Por fim, a temática mostrou-se eficaz para aprofundar e aplicar os conceitos de separação de misturas, trabalhados na Formação Geral Básica, conforme proposta da Base Nacional Comum Curricular para a educação básica.
Taxonomic morphometry of Juniperus phoenicea L. (Cupressaceae) from the coast of the Tlemcen region (western Algeria)
Authors: Korso Lamia Bouabdallah , Meziane Haciba , Babali Brahim , Chaouki Dib
Published: December 2024

The current study's objectives were to identify the subspecies of Juniperus phoenicea and conduct a morphometric comparison of 10 Juniperus phoenicea individuals found along the Tlemcen region's shoreline. First, we tallied how many seeds were present in 20 fruits from each particular species (in total 200 fruits). Measurements will be made for the second study's height, diameter, and circumference of the tree. The sheet's dimensions, as well as the berries' size and color. These data were statistically processed using statistical tools. The black size and color of the ripe fruits, which are frequently upright and found on the Mediterranean shore in dunes and stabilized rocks, were studied for all of the individuals (representing Juniperus phoenicea subsp. turbinata L.) based on the number of galbules, which ranges from (3-7). less dense port, which is frequently dug in the middle (in the trash). while demonstrating the phoenicea subspecies' absence and the existence of the turbinata subspecies. We were successful in eradicating the species' identifying characteristics, geographic distribution, and systematics along the coast of the Tlemcen region (Juniperus phoenicea L.subsp phoenicea).
Hemorragia digestiva alta: orientación diagnóstica y conducta actual sobre las estrategias terapéuticas, revisión bibliográfica
Authors: Quirós Pérez Jackeline , Herdoíza Morales Cristian Andrés , Segnini Miranda Jorge Andrés
Published: December 2024

La hemorragia digestiva alta constituye una de las causas de patología gastrointestinal de carácter urgente que amerita un diagnóstico y manejo expedito para reducir, de manera significativa, la morbimortalidad asociada.
Para clasificarla se puede dividir en variceal o no variceal. Para la enfermedad no variceal destaca la presencia de úlcera péptica como principal factor etiológico donde juega un papel importante la colonización por parte de la Helicobacter pylori (H.pylori). En el momento de evaluar al paciente se debe tomar en cuenta la historia previa de sangrado, ya que esta resulta importante a la hora de pensar en una recurrencia del mismo cuadro hemorrágico previo. Además, hay otros factores de riesgo que participan en la sospecha de esta patología. 
Es importante tomar en cuenta que existen diversos diagnósticos diferenciales los cuales se abordan a lo largo del artículo. Saber diferenciar cada uno permite un tratamiento y manejo adecuado.
Para el tratamiento existen tres etapas relevantes que deben seguirse en orden para garantizar el manejo más organizado posible y mejorar la supervivencia del paciente, los cuales son manejo pre endoscópico, endoscópico y post endoscópico.
Valor predictivo del Índice Neutrófilos- Linfocitos en lesionados ancianos con quemaduras extensas. Hospital Calixto García, Habana, Cuba
Authors: Zaldìvar Castillo Dayamí , Zamora Fernández Fernando , Aguirre Oramas Alberto Alejandro
Published: December 2024

El envejecimiento poblacional representa un desafío en el ámbito social durante las últimas décadas. En la vejez existe un aumento en la incidencia y prevalencia de enfermedades y traumas, constituyendo el trauma térmico una de las lesiones más devastantes que afectan al adulto mayor. La inmunodeficiencia senil ha sido señalada como uno de los factores que empeoran el pronóstico. El objetivo es determinar el valor predictivo del Índice neutrófilos-linfocitos en la aparición de complicaciones en el lesionado geriátrico con quemaduras extensas. Se realizó un estudio descriptivo, longitudinal y prospectivo, en la Unidad de Quemaduras del Hospital Universitario¨ General Calixto García, entre el 2021 -2023. Se incluyeron ingresados con quemaduras mayores de 25 % de superficie corporal y edades entre 60 y 90 años. Las enfermedades crónicas descompensadas e inmunodeficiencias constituyeron criterios de exclusión. Se determinaron los agentes etiológicos y mecanismos de producción del trauma. Se realizaron  determinaciones de índice neutrófilos linfocitos. Se diagnosticaron las complicaciones y se relacionaron con dichos valores. El universo de trabajo estuvo conformado por 96 lesionados. Predominó el sexo masculino, (51%). El grupo de 60 a 69 años fue el más afectado. El fuego directo fue el principal agente causal y prevalecieron los accidentes sobre otros mecanismos de producción. El 29 % de los lesionados sufrió complicaciones y el 94,8 % egresó vivo. Valores elevados de índice neutrófilos-linfocitos se asociaron a la aparición de complicaciones y mayor mortalidad. Se concluye que Índice neutrófilos linfocitos tiene un valor predictivo para el diagnóstico precoz de complicaciones en ancianos con quemaduras extensas.
الأنساق الثقافية في الشعر الجاهلي "عمرو بن كلثوم أنموذجاً"
Authors: Kadad Mustafa
Published: December 2024

: لقد نال الشعر الجاهلي مكانة رفيعة في الأدب العربي، حيث حاكى الشعراء اللاحقون لغته وصوره وتعبيراته، لما امتاز به من جمال اللغة وبلاغتها، وصوره الفنية الصادقة، وقدرته على تمثيل العواطف والطبيعة ببساطة وصدق. لكن لا يمكن الحكم على جميع شعراء الجاهلية بسمة واحدة بسبب تنوع أساليبهم وخصائصهم الفنية. لذا، وقع الاختيار في هذه الدراسة على عمرو بن كلثوم، لما له من أهمية ثقافية وسياسية واجتماعية في عصره. تناولت الدراسة مفهوم الأنساق الثقافية في شعره، مجاراة للاتجاهات الحديثة في النقد الثقافي، التي تسعى لتحليل النصوص الأدبية ضمن سياقها الثقافي بما يشمل المعتقدات والعادات والتقاليد الفنية. وقد أظهرت أهمية الأنساق الثقافية في إبراز القيم الجمالية للنصوص الأدبية وتحليلها، باعتبارها منظوراً جديداً في دراسة الأدب يتجاوز النقد التقليدي.
What are the Cohesive Devices in Opinion Essays Written by Turkish EFL Students across Different Proficiency Levels?
Authors: Subasi Gonca , Uner Seda
Published: December 2024

Effective writing requires important features and one of them is cohesion which is necessary to bind a text. Halliday and Hasan (1976) state that grammatical and lexical devices which are called cohesive devices (CDs) create texture. To make a text coherent and understandable, CDs should be used frequently and skilfully. The present study aims to investigate the students’ employment of CDs in a specific genre. The participants were 60 EFL students enrolled in the beginner and pre-intermediate preparatory classes at a state university in Turkey. The student’s opinion essays were examined via the modified version of Halliday and Hasan’s (2001) taxonomy of CDs developed by Yang and Sun (2012). The collected data were analysed by calculating the frequency of CDs and comparing the means of CDs used correctly or incorrectly by the participants. The outcomes yielded that the pre-intermediate level students used cohesive devices more frequently and accurately in their opinion essays compared to the beginner-level students. In addition, it was diagnosed that the most problematic area for both levels was the use of conjunctions. Hence, as a pedagogical implication, it is recommended that cohesive devices be taught at the core of writing instruction.
Investigation of The Inhibition of SARS-CoV-2 Spike RBD and ACE-2 Interaction by Phenolics of Propolis Extracts
Authors: Ay Fulya , Güler Halil İbrahim , Çanakçı Sabriye , Beldüz Ali
Published: December 2024

The molecules that consist of propolis are generally polyphenols, and they have many activities such as antiviral, antibacterial and antifungal activities. In this study, it is aimed to investigate the inhibiting capacity of the interaction between ACE-2 and Spike RBS by propolis samples belong to three different cities (Trabzon, Kocaeli, Kırıkkkale). After determining the propolis sample exhibiting the highest inhibition effect, the phenolics within this sample were identified, individual assessments of the inhibition effects of each phenolic compound were conducted with Spike S1 (SARS-CoV-2): ACE2 Inhibitor Screening Colorimetric Assay Kit and supported by docking studies in silico. Propolis sample with the highest inhibition effect was determined as 'Kocaeli'. Then, the pure molecules known to be present in Kocaeli propolis were tested and found that p-OH benzoic acid, syringic acid, ferulic acid and gallic acid did not have any inhibitory effects on the Spike S1 (SARS-CoV-2): ACE2 interaction. The substances with the greatest inhibitory effect are; protocathecuic acid, caffeic acid, p-coumaric acid with the inhibition of 62.29%, 58.34%, 59.20%, respectively. The lowest IC50 value of the flavonoids was found to be 0.89 mM with caffeic acid. Over all in silico, in vitro experiments, and MTT analyses conducted in the literature have demonstrated that caffeic acid and protocatechuic acid can be used as a highly active compound against COVID-19.
Potential geographic accessibility to municipal medical services (Cruz Verde) in the municipality of Guadalajara, Jalisco, Mexico
Authors: Ortiz-Curiel Yaireth Deyanira , Niño-Gutiérrez Naú Silverio , Andrade-García María Dolores , Macías-Huerta María del Carmen
Published: December 2024

This research evaluated the potential geographic accessibility of the population in the municipality of Guadalajara to the municipal medical services units, considering distances and road barriers. The central objective was to analyze how the location of health units and road infrastructure influenced the population's access to these services. A quantitative approach was adopted, using a potential geographic accessibility index based on spatial analyses conducted with QGIS. The results showed that units located in the center of the municipality, such as Dr. J. Jesús Delgadillo Araujo, had greater accessibility, while those located on the outskirts, such as Dr. Leonardo Oliva Alzaga and Dr. Mario Rivas Souza, showed lower levels of access. It was concluded that the planning of health services must consider both geographic distribution and road infrastructure to improve equity in health access.
Dark Agoras: Insurgent Black Social Life and the Politics of Place
Authors:   State University of New York at Buffalo, Ujie Diamond Alissa
Published: December 2024

Historian and urbanist J. T. Roane’s debut book Dark Agoras traces Black worldmaking practices, socialities and spatial politics from the enslavement-era rural Upper South to twentieth-century urban Philadelphia. Roane takes readers through geographies and communities connected by the Great Migration, the mass movement of Black workers from the rural South to the urban North. For Roane, dark agoras are the gathering spaces enslaved and working-class Black people created beyond institutional surveillance and control. Drawing on analytical frames from Black, Indigenous, religious, phenomenological, geographic and ecological thought, Roane brilliantly makes visible the Black worldmaking practices that have always existed alongside and in tension with the plantation and the capitalist city. This work is vital in a moment when much urban history focuses on structures of oppression. Critical scholarship of this type is vital for understanding how the production of American urbanism is entangled with racism (see for example Rothstein, The Color of Law, 2017). But critique has its limitations, and it can overstate oppressive systems’ relative power and success. Attending to historical resistances and alternatives, as Roane’s book does, can expand pathways for design actors to maneuver within these systems.
Space and Context: Exploration of Information Experience and Document Experience
Authors: Boettcher Carrie
Published: December 2024

This paper explores documents that are recorded and cataloged, but the original is a one-of-a-kind phenomenon that only exists once. It ponders where information ends, and document begins and the concepts of space and context that contribute to the shape or structure of the document. Specifically, the confidential counseling session, only experienced by the individuals present during the session, repeated but not duplicated, and how information and documents contribute to understanding of the counseling session.
Dette entrée en communauté du chef d’un époux et saisie‑attribution d’un compte joint : sur qui pèse la charge de l’identification des fonds saisis ?
Authors: Pierre Nathalie
Published: December 2024

Lorsque le créancier d’un époux commun en biens fait diligenter, au titre d’une créance de prêt, une saisie-attribution sur un compte dont sont cotitulaires les époux, comment s’applique concrètement l’article 1415 du Code civil, limitant le droit de gage du créancier aux propres et revenus de l’époux débiteur ? Alors que, en l’espèce, les époux n’établissaient ni qu’ils étaient soumis au régime légal de communauté ni que le compte était alimenté par les revenus des deux époux, la Cour d’appel de Grenoble fait peser la charge de l’identification des revenus du débiteur parmi les éléments fongibles du compte sur les époux et non sur le créancier. La pleine portée de l’arrêt est à établir, alors que la Cour de cassation, dans le cadre d’une jurisprudence constante, met à la charge du créancier la preuve de l’origine des fonds saisis.
De la caractérisation de la faute du gérant et du préjudice individuel de l’associé
Authors: Vicente Serge
Published: December 2024

Un associé égalitaire de SARL engage une action individuelle en responsabilité à l’encontre de son gérant coassocié en invoquant la prise en charge non autorisée de ses cotisations sociales par la société ainsi que la conclusion de ventes d’actifs à des prix soldés. L’arrêt rendu retient l’attention par la caractérisation tant de la faute du gérant que du préjudice individuel de l’associé.
Quelques rappels utiles relatifs à l’exception préjudicielle d’illégalité
Authors: Ratineau Yannick
Published: December 2024

L’exception d’illégalité d’un acte administratif doit être présentée par les parties avant toute défense au fond devant la juridiction de première instance pour pouvoir être ultérieurement soulevée en cause d’appel‚ ce d’autant que si le juge pénal dispose de la faculté de soulever d’office l’illégalité d’un acte administratif‚ c’est à la condition toutefois que l’examen de la légalité de l’acte dépende la solution du procès pénal conformément à l’article 111‑5 du Code pénal.
Pengujian Earning Management dan Leverage Terhadap Efisiensi Investasi
Authors: Perdana Djaja
Published: December 2024

This research aims is to investigate the effect of earnings management and leverage from business activities in the previous period on investment efficiency in the current period. The sample consisted of 46 banking companies listed on the Indonesia Stock Exchange during the 2019-2023 period and was selected using a purposive random sampling technique. The data obtained was 195 after deducting outliers and then analyzed using multiple regression. The results of this research prove that earnings management practices in the previous period had a significant negative effect on overinvestment in the current period. These earnings management practices also correlate with the level of liquidity in the same period. Meanwhile, leverage in the previous period had a significantly positive effect on underinvestment in the current period especially in large companies.
Pengujian Determinan Kinerja Keuangan Pada Perusahaan Manufaktur Di Indonesia
Authors: Dewi Maria Rosa Kumala , Kristantiningtyas Dhian , Dwiyani Titik
Published: December 2024

This research was conducted to examine the influence of environmental performance, environmental costs, and company size on financial performance. The research was conducted on manufacturing companies listed on the Indonesia Stock Exchange (BEI) in the 2018-2021 period that met the sample criteria. The 2018-2019 period is categorized as conditions before the Covid-19 pandemic in Indonesia, while the 2020-2021 period is categorized as conditions during the Covid-19 pandemic in Indonesia. The research results show that in two conditions, environmental performance influences financial performance. In conditions before the Covid-19 pandemic, environmental costs had an effect on financial performance, whereas during the Covid-19 pandemic environmental costs had no effect on financial performance. In two conditions, company size has no effect on financial performance.
Análisis cognitivista de la semántica resultativa de los verbos sintagmáticos con chu (出‘fuera’) en chino
Authors: Wang Yuan
Published: December 2024

Being a satellite frame language, Chinese abounds in [verb + directional particle] constructions (V+DP). Semantically, V+DP expresses literal movement and resultative aspect, indicating the culmination of the event. When denoting resultative aspect, the amalgamation of the verb and the DP corresponds to the linguistic phenomenon of the phrasal verb (PV). The lexical meaning carried by a specific DP endows the resultative PV with unique meanings. This paper analyzes the semantic behavior of the resultative PV formed with chu (出 ‘out’), one of the most frequent DPs, from a cognitive approach. By analyzing data extracted from the BCC Corpus (BLCU Corpus Center), we have observed certain significant patterns. The results have shown that the semantic behavior of the resultative PV with chu (出 ‘out’) is suitable for representing the concept of ‘visibility’, motivated by the container image schema. This concept acts, first, as a source domain for figurative meanings such as ‘understand’. Secondly, it reflects in various specific interpretations linked to container metaphors. Therefore, it is concluded that the cognitive analysis allows us to distinguish the PV with chu (出 ‘out’) from the V+chu (出 ‘out’) grammatical constructions, establishing it as a consolidated lexical unit. This study provides a deeper understanding of the PV with chu (出 ‘out’) in Chinese and suggests future research in intercultural comparison and pedagogical applications in teaching Chinese as a foreign language.
Inferencias en memes y noticias digitales sobre política: una prueba de comprensión multimodal en estudiantes universitarios costarricenses
Authors: Chavarría Ortiz Wendy , Vergara Heidke Adrián , Cambronero Alejandro
Published: December 2024

When we encounter a political event, heated discussions are often generated on social media, which are complemented by memes and digital news. This highlights the need to explore how these texts are understood. The aim of this research is to describe the inferences made by students of Business Administration at the National University after exposure to these texts, using a test designed to assess inferences. A qualitative approach was applied, with an initial pilot, expert reviews, and the evaluation of 40 first- and fourth-year students through six stimuli (three memes and three digital news articles). The results revealed that memes generated more expected inferences (91.67% recognition of referents) compared to news articles (63.33%), as well as a higher identification of logical-semantic relationships in memes (82.5%) compared to news articles (30%). It was found that the focus on building optional inferences related to news was mainly verbal (94.7%), while in memes, most of the focus was on integration (59.10%), followed by the graphic mode (22.72%). Finally, the most common intentions were those specific to each genre. The paper concludes with recommendations for future research on multimodal texts.
Extraction of Ocimum Basilicum and Its Application inSynthesis of Transdermal Patches for Medical Applications
Authors: *Ms. Akshaya A *Ms. Akshaya A , Sivapriya S Sivapriya S , Praneesh S Praneesh S
Published: December 2024

This invention relates to the extraction of bioactive
compounds from Ocimum basilicumfor transdermal
patch development in medical applications. The
method utilizes efficient techniques for isolating
therapeutic constituents, including essential oils and
flavonoids. These compounds are formulated into a
patch matrix that ensures controlled transdermal
release. The patches present a non-invasive
alternative to traditional drug delivery, enhancing
patient compliance while reducing gastrointestinal
side effects. They are engineered to maintain the
stability and efficacy of active ingredients,
facilitating effective therapeutic delivery. This
invention encompasses the techniques for
extraction, formulation processes, and evaluation
methods for these patches. The primary objectives
include enhancing the therapeutic potential of
Ocimum basilicum, ensuring formulation safety,
and providing effective treatments for conditions
like pain and inflammation. The significance of this
invention lies in its ability to integrate natural
extracts into modern medicine, offering a
sustainable and patient-centric drug delivery
method. By utilizing the medicinal attributes of
Ocimum basilicum, this invention aims to develop
a versatile and effective transdermal delivery
system for diverse therapeutic purposes
Transdermal Drug Delivary System
Authors: Sudhakar Mhaske Rameshwar , Pratik Baban MrBhanage , Salve Dr megha
Published: December 2024

Many noninvasive administrations have recently e
merged as alternatives to conventional needle inject
ions.The transdermal drug delivery system (TDDS)
, which has a low rejection rateremarkable ease of a
dministration, and remarkable patient convenience
and persistence, is the most alluring of all.TDDS m
ay be useful not only in the pharmaceutical industr
y but also
in the skin care industry, which includes cosmetics.
Because this method focuses on local
administration, it can prevent local drug
concentration accumulation and nonspecific drug
distribution to tissues that are not the medication's
target. There has been a lot of research on
techniques to overcome the various
physicochemical properties of the skin that hinder
transdermal delivery. In this review, we enumerate
the several types of TDDS methodologies now in
use and critically analyze their unique advantages
and disadvantages, characterization methods, and
potential.Research on these alternative ways has
advanced, demonstrating the high efficiency of
TDDS, and it is expected that these technologies
will be used in many different industries
“Enhancing Idli Pre-Mix: Incorporation of Black Cumin Seeds (Nigella sativa) for Improved Nutritional and Functional Properties”
Authors: Abdul Gafoor Abdul Gufran , Bornare Dr. Deepak , Jaiswal Dr.Swapnil
Published: December 2024

Fermented foods and beverages have been integral
to human diets for centuries, produced either
spontaneously or with the addition of starter
cultures. This process Beverages local raw
materials from plants or animals, transforming
them through the activity of microorganisms. These
microorganisms enhance the nutritional and
biochemical properties of the raw materials,
improving taste, texture, and aroma. The methods
of producing and consuming fermented foods vary
across different cultures and ethnic groups. Despite
their numerous health benefits, the consumption of
fermented foods globally is declining due to the
effects of globalization and changing dietary habits.
In India, some of the most popular fermented foods
include idli, dosa, appam, porridge (koozh), dhokla,
gundruk, dahi, sinki, rumba, fermented rai, kanji
ka, and handua. These foods were traditionally
favored for their extended shelf life achieved
through acetic acid and alkaline fermentations.
Fermentation enriches foods biologically,
increasing the content of proteins, essential amino
acids, essential fatty acids, and vitamins, while
reducing anti-nutrients. This process also enhances
flavor and aroma, improves digestibility, and offers
various health benefits.
Prognosis and Treatment Selection in Appendicitis: Insights from Alvarado Score, Appendicitis Inflammatory Response Score, NLR and PLR
Authors: Jeeva P G Jeeva P G , Niranjana E S Niranjana E S , Elavarasi K Elavarasi K , Liju L Liju L
Published: December 2024

Appendicitis ranks among the leading causes of
acute abdominal pain in both adults and children.
Scoring systems like the Alvarado score, while
established and validated, have drawbacks that
newer systems like the AIR score aim to overcome.
The aim of the study is to investigate if certain
predictive markers can be helpful in identifying
appendicitis early and guiding the selection of
appropriate treatments. The Retrospective study
conducted in Tamil Nadu for 6 months. The study
include 206 patients with acute appendicitis.
Statistical analysis was conducted using IBM's
SPSS. The research involved a male majority
(54.37%) with all patients displaying right lower
quadrant tenderness. Most cases (77.67%) opted
for laparoscopic appendicitis surgeries. Notably,
there was a marked NLR ratio difference between
laparoscopy and laparotomy patients, favoring
higher NLR ratios. Alvarado scores varied
significantly across different appendicitis
inflammatory response levels. The study
highlighted a strong positive correlation between
NLR and PLR ratios, as well as with appendicitis
inflammatory response scores. It also indicated a
positive association between variables, suggesting
a trend towards higher values in one corresponding
to higher values in the other. This study concluded
that a significant association among the Alvarado
score, Appendicitis Inflammatory Response (AIR)
score, Neutrophil-to-Lymphocyte Ratio (NLR), and
Platelet-to-Lymphocyte Ratio (PLR) in patients
with acute appendicitis.
A Study on Drug Utilization and Drug Interaction on Antibiotics in the Orthopedic Patients
Authors: Sethuraman K Sethuraman K , Shalini S Shalini S , Ishwarya Roy Sharon , Philips Merin levy , GokulaKrishnan GokulaKrishnan
Published: December 2024

A study entitled "Drug Utilization Evaluation and
Drug Interaction of antibiotics in orthopedic
patients” was conducted in the department of
orthopedics of a 1000 bedded multispecialty
private hospital. The prospective observational
study was conducted for a period of six months. A
total of 70 cases were collected and study was
conducted. The Maximum number of patients were
in between the age group of 39-59 years (41%),
followed by 25 patients (36%) between the age of
60-90 years, then 16 patients (23%) between 18-36
years. Based on diagnosis, 37
patients (53%) were diagnosed with Fracture, 11
patients (15%) with Osteoarthritis, 2 patients (3%)
with Osteomyelitis.The length of stay of the study
population was analyzed and it was observed that,
43 patients (62%) stayed less than or equal to 5
days. Among the 70 patients, 45 (64%) were
prescribed with one antibiotic, 20 (29%) with two
antibiotics and 5 (7%) with 3 antibiotics.
Cephalosporin’s were prescribed to 53 patients
(76%). Drug interactions were identified, with 94
interactions, 47% major, 28% moderate and 25%
minor.
Transforming Healthcare: The Potential of Personalized Medicine in the Era of Precision Health
Authors: S. Wadatkar Miss. Jagruti , Kohale Dr. Nitin B , M Jawalkar Mr. Gajanan , S Sawarka Dr. Harigopal
Published: December 2024

Personalized medicine (PM) is about tailoring a
treatment as individualized as the disease. The
approach relies on identifying genetic, epigenomic,
and clinical information that allows the
breakthroughs in our understanding of how a
person’s unique genomic portfolio makes them
vulnerable to certain diseases. PM approach is a
complete extension of traditional approach (OneSize-Fits-All) to increasing our ability to predict
which medical treatments will be safe and effective
for individual patient, and which ones will not be,
based on the patient’s unique genetic profile.
Implementation of PM has the potential to reduce
financial and time expenditure, and increase quality
of life and life extension of patients. Knowledge of
PM facilitates earlier disease detection via
enhanced use of existing biomarkers and detection
of early genomic and epigenomic events in disease
development, particularly carcinogenesis. The PM
approach predominantly focuses on preventative
medicine and favours taking pro-active actions
rather than just reactive. This approach delays or
prevents the need to apply more severe treatments
which are usually less tolerated and with increased
quality of life and financial considerations.
Increasing healthcare costs have placed additional
pressure on government funded healthcare systems
globally, especially regarding end of life care. PM
may increase the effectiveness of existing
treatments and negate the inherent problems
associated with non-PM approaches. PM is a young
but rapidly expanding field of healthcare where a
physician can select a treatment based on a
patient’s genetic profile that may not only
minimize harmful side effects and guarantee a
more successful result, but can be less cost
effective compared with a ‘trial-and-error’
approach to disease treatment. The less efficient
non-PM (‘trial-and-error’) approach, which can
lead to drug toxicity, severe side effects, reactive
treatment and misdiagnosis continue to contribute
to increasing healthcare costs. Increased patient
stratification will allow for the enhanced
application of PM and pro-active treatment
regimens, resulting in reduced costs and quality of
life enhancement.
Integrative Approaches to Endometriosis: Ayurvedic and Modern Perspectives on Comprehensive Management
Authors: Wagh Dr. Sonal
Published: December 2024

Endometriosis is a complex gynaecological
condition characterized by the presence of
endometrial tissue outside the uterine cavity,
leading to chronic pelvic pain, infertility, and a
significant impact on quality of life. Although
modern medical interventions, including hormonal
therapy and surgery, are commonly used to manage
the condition, limitations such as recurrence and
side effects often exist. Ayurveda, an ancient
system of holistic medicine, offers alternative
perspectives on the management of endometriosis.
This article explores the Ayurvedic understanding
of endometriosis in relation to its aetiology,
pathology, and treatment modalities, including
Panchakarma (detoxification therapies) and the use
of herbal formulations such as KanchanarGuggulu,
Shatavari, and Ashwagandha. Additionally,
integrative approaches combining Ayurvedic
therapies with contemporary practices like diet
modification and yoga are discussed. By merging
the wisdom of Ayurveda with modern scientific
insights, this article aims to provide a
comprehensive approach to managing
endometriosis and improving patients' overall
health outcomes.
Reflexive organization of decision-making process in youth
Authors: Buherko Jaroslava , Kuzmynska Dina
Published: December 2024

The article considers reflection as a complex multi-aspect phenomenon, which is described from the conceptual positions of various theoretical approaches that causes different quality of filling its category-conceptual content and ambiguous certainty of place in the system of psychological knowledge. The phenomenological complexity of a structural-functional organization of reflexive activity objectively causes difficulties in determining its qualitative filling-with-content and specificity. It is proved that reflection can be described as the ability of a person to realize, and therefore to organize and regulate his own mental processes, states, properties, tendencies, and as a complexly structured psycho-conscious process, and as an integral mental property, and as a metastate, that is, as a superstate, the meaning of which is in awareness and subsequent possibility of the personality’s regulation of his own psycho-spiritual states. It is argued that the development of reflexive issues in the field of national education acquires special importance. The use of various training reflexive practices contributes to the development of creative reflexivity, which is an important component of personality’s creative in-depth self-cognition and self-construction. One of the universal socio-psychological forms of a specific-practical organization of parity educational activity in high school, which ensures the full-fledged development of reflection, is the model of a full functional cycle of the educational module proposed by A.V. Furman. Analysis of the information-cognitive period of modular-developmental education indicates a significant development of reflexive components in the search cognitive activity of high school students and students, which contributes to the intensive formation of such an important personality’s property as the ability to make decisions independently. It has been substantiated that reflexive organization of the decision-making process in an educational problem situation contains the following stages: a) subject-operational movement-advance of thought in the process of finding a solution-removal of the problem situation; b) reflexive-subject transformation of an educational problem situation; c) activation of the need for understanding and rethinking of educational-cognitive tasks and educational assignments; d) active self-restructuring of the inner world of a subject, associated with the exit to a reflexive position and deciding to act.
Optimization of psychologists’ professional responsibility formation
Authors: Lypka Arsen
Published: December 2024

The article substantiates the formulation of recommendations for optimizing the development of professional responsibility among modern university’s students-psychologists; it is highlighted that the essence of optimization is to choose the best option or method of action-deed out of a set of possible directions or versions from the standpoint of the best circumstances and the least used resources, the time spent and the efforts made; basic principles and rules for strengthening the components of the future psychologists’ professional responsibility are proposed; it has been analyzed the signs-characteristics of irresponsible behavior in order for each of them not to get into the nets of personal degradation; psychological steps that the successor must take in order to cultivate responsibility as a personal trait-quality are outlined; an ethical alphabet of professional responsibility is suggested, which includes prescriptions, recommendations, according to which a person can act as a specialist in his business; it is described that the psychologist’s professional responsibility is his basic (fundamental) socio-psychological property or characteristic as a competent specialist, which is produced (formed) by him during professional activity.
COOPERATIVISMO FINANCIERO: ANÁLISIS COMPARATIVO DE LA ESTRUCTURA REGULATORIA DE LAS ORGANIZACIONES DE ECONOMÍA SOCIAL DEL SECTOR FINANCIERO COOPERATIVO EN COLOMBIA Y ESPAÑA
Authors: Galvis Macias Ivan Humberto
Published: December 2024

El sector de la economía social o solidaria se encuentra regulado en los ordenamientos jurídicos colombiano y español a partir de diversos instrumentos normativos que lo asocian, en el primer caso, al desarrollo de actividades sin ánimo de lucro. Forman parte de este sector, entre otras organizaciones, las denominadas cooperativas financieras. El presente trabajo pretende realizar un análisis comparativo de los principales aspectos regulatorios aplicables a estas entidades en uno y otro ordenamiento, con el fin de ubicarlas dentro de las organizaciones de la economía social e identificar posibles modificaciones normativas que permitan que el mismo sector pueda operar de una manera más eficiente y con más cobertura en el mercado colombiano. Del análisis realizado se concluye que para esta finalidad es necesario ajustar el funcionamiento de las cooperativas financieras adaptándolo al concepto de economía social, permitir en ellas la participación de personas mercantiles, ajustar los capitales mínimos a contextos territoriales, implementar sistemas institucionales de protección y permitir la ejecución de las demás operaciones habilitadas a los establecimientos de crédito.
ACERCA DE LAS (IN)VISIBILIZACIONES DE LA ECONOMÍA SOCIAL Y SOLIDARIA. UN TRABAJO SOBRE LAS AGENDAS DE LOS MEDIOS DIGITALES DE SAN LUIS, ARGENTINA
Authors: Hidalgo Ana Laura , Galende Belén del Carmen
Published: December 2024

La presente contribución se propone sistematizar un trabajo de campo realizado durante los años 2020-2021 sobre las agendas de los medios digitales de la provincia de San Luis, Argentina.El estudio parte en considerar el lugar que ocupan las noticias referidas a las prácticas de la Economía Social y Solidaria (ESS) en la agenda de los medios seleccionados y cómo estos se visibilizan respecto de otros contenidos. Para ello, además, se recurre a relevar contribuciones precedentes a partir de estudios similares que sientan jurisprudencia en temas afines.El artículo organiza la información obtenida en gráficos que permiten comprender la escasa presencia de este tipo de actores en las agendas mediáticas digitales en San Luis y delinea futuras líneas de estudio sobre la cuestión.
KOSMETOLOGŲ ŽINIOS APIE BIOTECHNOLOGIJOS PAGRINDU SUKURTŲ INGREDIENTŲ POVEIKĮ SENSTANČIAI ODAI
Authors: Barragan Ferrer Diana , Povilionytė Diana , Mickienė Žaneta
Published: December 2024

Biotechnologijų vystymasis skatina inovacijas įvairiose pramonės šakose, įskaitant grožio industriją. Naudojant fermentacijos procesus ir genų inžineriją, kuriamos odos senėjimą lėtinančios molekulės, veikiančios odą ląstelių lygmenyje ir mažinančios senėjimo požymius. Žinios apie biotechnologinius ingredientus ir jų poveikį sens­tančiai odai yra esminė šiuolaikinių grožio specialistų darbo dalis, leidžianti jiems teikti efektyvias, saugias ir individualizuotas odos priežiūros paslaugas. Šiame tyrime buvo siekiama išsiaiškinti, ar kosmetologai turi pakankamai žinių apie šiuos inovatyvius ingredientus ir ar tikslingai juos įtraukia į savo darbą sprendžiant odos senėjimo problemas. Tyrimo metu buvo atlikta anketinė apklausa. Rezultatai parodė, kad dauguma kosmetologų turi žinių apie biotechnologijos pagrindu sukurtų ingre­dientų poveikį odai, o žinių lygis koreliuoja su darbo pa­tirtimi – ilgesnę patirtį turintys specialistai turi daugiau žinių. Vis dėlto, respondentai pripažino turintys nepa­kankamai žinių apie kai kuriuos specifinius ingredientus, tokius kaip peptidai, termofilinės bakterijos ir biotech­nologiniu pagrindu sukurtų medžiagų kilmę.
NAUJŲ DARBUOTOJŲ ADAPTACIJA DARBO RINKOJE: AKUŠERIŲ PATIRTYS
Authors: Vaškelytė Alina , Laimutytė Akvilė
Published: December 2024

Adaptacija – tai dinamiškas procesas, kurio metu in­dividai prisitaiko prie naujų sąlygų, aplinkos ar situa­cijų, kad išlaikytų arba pagerintų savo funkcionalumą ir gerovę. Jaunų specialistų, pradedančių dirbti sveikatos priežiūroje, adaptacijos procesas gali apimti dvi pagrin­dines adaptacijos rūšis: profesinę ir socialinę. Siekiant atskleisti ką tik studijas baigusių ir pirmoje darbovietėje įsidarbinusių akušerių adaptacijos patirtis, buvo atliktas kokybinis tyrimas taikant individualų pusiau struktūruotą interviu metodą. Tyrime dalyvavo 11 akušerių, dirbančių Kauno miesto gimdymo stacionaruose. Tyrimo radiniai atskleidė, jog adaptacijos procesas apima ne tik žinių ir įgūdžių įgijimą, bet ir integravimąsi į socialinę darbo vietos struktūrą bei profesinio tapatumo ugdymą. Akuše­rėms tenka ne tik tobulinti savo klinikinius įgūdžius, bet ir išmokti laviruoti tarp profesinių ir asmeninių santykių su kolegomis, tampant visaverčiu komandos nariu. Adap­tacijos periodu akušerės išgyvena platų emocijų spektrą. Pirmomis dienomis jas lydi nerimas, baimė, noras viską mesti, tačiau su didėjančia kompetencija auga atsparumas stresui, darbas pradeda teikti daugiau džiaugsmo, didėja pasitikėjimas savimi, atsiranda pasitenkinimas darbu ir užtikrinami geresni darbo rezultatai.
INFLUENCE OF CLIMATIC CONDITIONS OF BESSARABIA ON THE EPIZOOTOLOGY OF INTESTINAL STRONGYLATOSIS OF SHEEP
Authors: Bogach M. V. , Bondarenko L. V.
Published: December 2024

The development of gastrointestinal nematode parasites of sheep depends significantly on the climate. Extreme heat and cold have a negative effect on the development and survival of helminth larvae, while an increase in temperature, within acceptable values, usually accelerates their development. Moisture is necessary for the development and movement of larvae from feces to pasture, so the amount of precipitation is a limiting factor for the transmission of infestation. Together, these factors determine the seasonal dynamics of sheep infestation, as well as geographic variation in epizootology. Thus, the effects of climate change are particularly important for the spread of parasitic helminths because of its potential to affect their free-living stages and their intermediate hosts.
The purpose of the work: to find out the distribution of gastrointestinal parasites in sheep in the farms of Bessarabia, taking into account hydrometeorological conditions in 2023 and 2024.
The main criterion during the epizootological survey of farms was the level of sheep infestation by nematodes Trichostrongylus colubriformis, Strongyloides papillosus, which parasitize in the small intestines, and Oesophagostomum venulosum, which parasitizes in the large intestine. In 2023, a total of 1,019 sheep were examined, and in 2024, 795 sheep of different age groups from sheep farms in Bessarabia. Helminthoscopy of faecal samples was performed using a modified McMaster technique with a minimum detection level of 20 nematode eggs per gram of faeces. The intensity of the invasion was determined using a quantitative helminthocoprological study (Stoll's method).
Atmospheric precipitation is one of the least stable climatic factors, and at the same time, its volume and seasonal distribution in the south of Ukraine affect the distribution of gastrointestinal parasites in small cattle. According to the data of the hydrothermal coefficient, the climate of Bessarabia in 2023 was quite humid, while the climate of 2024 was characterized by severe drought. In 2023, the total infestation of sheep with strongylids was 40.8%, while in 2024 it was only 26.8%, which is 34.3% less.
The maximum indicators of strongylidosis extensiveness in sheep were recorded in May 2023 during a period of sufficient moisture (65.5%) and in June (65.7%), when moderate drought conditions had set in, but a substantial release of helminth eggs (391.09±8.13 EPG) was still observed. In the dry year 2024, the peak infestation was recorded only once in April (51.7%) and a slight increase in September to 33.7% due to increased humidity. During the four dry summer months, the incidence of strongylids in sheep was at a low level of 19.1% to 24.5%.