bluuebunny/crossref_metadata_2025 huggingface dataset:
Pelatihan Kerajinan Pot dari Semen dan Handuk Bekas Guna Menumbuhkan Kreativitas Masyarakat
Authors: Nasrulloh M Farid , Khotimah Khusnul , Khotimah Khusnul , Hariyanti Wiwid Ika , Rochmawati Siti
Published: August 2022

Residents who live in this area on average plant certain types of flowers in flower pots, they buy flower pots at a fairly high price. Flowers with aglonema type need a pot as a place to grow. This community service activity is carried out to foster knowledge and understanding of PKK mothers and IPNU and IPPNU youth in utilizing unused objects that can be processed into products that have added value and are very useful which is termed Upcycle. The pot training activity from used cloth is carried out to train the community to use used cloth which can be a product that has high artistic value. This community service activity uses a training method for making pots from cement and used towels. The results of this activity are (1) It can foster the creativity of PKK mothers and IPNU IPPNU teenagers in utilizing used goods such as used towels. (2) PKK mothers and IPNU IPPNU youth have new knowledge about the utilization of unused used goods in the surrounding environment to be processed into useful products and have a high buying and selling value. (3) PKK mothers and IPNU IPPNU youths can save money on buying similar products that can be made by themselves.
Pelatihan Perencanaan Keuangan Santri di Pondok Pesantren Bustanul Mansuriyah
Authors: Fariduddin Fahriyan , Saputra Edi , Busthom Aby Yazid Al , Adinugraha Hendri Hermawan
Published: August 2022

This financial planning training service program for students at the Bustanul Mansuriyah Islamic Boarding School aims to share knowledge and practical training in management knowledge in preparing monthly budgets and provide insight into the urgency of professional financial planning management to raise awareness of better personal financial management for students in Islamic boarding schools. Bustanul Mansuriyah Islamic Boarding School. The method applied to this service activity is the method of direct material decomposition as well as simulations and dialogues regarding management, financial management and intensive assistance in personal financial planning with a problem solving approach that has an impact on the welfare of students. The result of this community service is mentoring in proportional financial planning management and data obtained on average students have the ability to prepare personal financial planning well.
Pelatihan Pendesainan Perangkat Pembelajaran yang Melibatkan Literasi Matematika untuk Guru Sekolah Menengah
Authors: Gustiningsi Tria , Putri Ratu Ilma Indra , Zulkardi Zulkardi , Inderawati Rita , Kurniadi Elika , Herlina Rini , Rahayu Chika , Lisnani Lisnani , Malalina Malalina , Rawani Dewi , Sari Arika , Septimiranti Delia
Published: August 2022

This activity is carried out with the aim of understanding secondary teachers about learning tools that involve mathematical literacy. The methods used are training, discussion, and mentoring. Training and discussions were carried out using zoom for two days, while mentoring was carried out using google classroom for one month. The target of this activity is secondary teachers in Pagaralam City, South Sumatera. Evaluation is carried out by giving assignments to teacher and providing a satisfaction questionnaire for implementation. The results show that teachers are satisfied with the overall implementation of the activity and teachers understand learning tools that involve mathematical literacy, teachers can design tools well and test them out on students.
Pelatihan Strategi Pemecahan Masalah Matematika Nonrutin Sebagai Persiapan KSN Matematika Di SMP Al Irsyad Purwokerto
Authors: Kartika Dwiani Listya , Pratama Dian , Sofiyati Noor
Published: August 2022

The purpose of this service activity is to introduce, prepare and increase students' knowledge, especially students of mathematics achievement at SMP Al Irsyad Al Islamiyah Purwokerto about effective and efficient as a provision to take part in the National Science Competition in the field of mathematics or other similar math competitions. So far, the selected students are given independent guidance by the teachers at the school. However, due to scientific limitations and the teacher's busy schedule, the activity of building mathematics achievement is still not optimal. The method of implementing this activity consists of three stages starting with the first stage, namely the introduction of mathematical problem solving strategies, followed by the second and third stages in the form of material deepening activities. The post-test results showed an increase in the average post-test score of 22% from the average pre-test score. This shows an increase in the non-routine mathematical problem solving ability of the participants after being given training. The results of observing participant activities for three meetings also showed that the percentage of activity during the training increased at each meeting. This shows the increasing ability and motivation of the trainees in solving non-routine math problems.
Keywords: Problem Solving, Non-routine Mathematics Problems, National Science Competition
Pelatihan dan Pendampingan Maharah Kalam Santri dalam Pembelajaran Bahasa Arab di TKA/TPA
Authors: Amir Nurazizah , Nurjannah Nurjannah
Published: August 2022

Arabic is familiar to Muslims because the main source of teaching is the Qur'an and hadith, both of which use Arabic. In addition, the books of scholars in the field of Islamic sciences also use Arabic. Thus, Arabic is an urgent language to learn as Muslims. However, the Indonesian people, especially the millennial generation of students, still regard Arabic as a very difficult language to learn. Therefore, providing an understanding of the importance of learning Arabic needs to be done to the community so that they are able to recognize their identity as Muslims as a whole. Speaking skill (maharah kalam) is one of the most important aspects in learning Arabic because learning a foreign language will be easy if you are actively involved in communication efforts. Therefore, the author held training and mentoring activities for maharah kalam in learning basic Arabic at TKA/TPA Al-Ikhsan, Congkoe Hamlet, Lamatti Riaja Village, Bulupoddo District. The result of this activity is that in the process of learning Arabic, students show an enthusiastic attitude in receiving learning materials. This can be seen from their enthusiasm for learning, enthusiastic attitude in practicing vocabulary or conversation in front of friends, asking questions about the material that has been presented, and responding well to questions asked. Thus, the results of the learning evaluation show that students who have never studied Arabic are able to know well the lessons that have been taught and can pronounce Arabic vocabularies properly and correctly.
Pendampingan Peningkatan Kemampuan Bahasa Inggris Santri di Pondok Pesantren
Authors: Bahtiar Yuyun , Fikri Ahmad Kanzul , Khasibah Nur
Published: August 2022

In addition to studying in formal schools, Students (Santri) can also study in non-formal schools such as participating in training to increase their understanding of a lesson. However, to be able to participate in the training certainly costs a lot. The symptoms found were that some of the students came from underprivileged families, found it difficult to divide study time with their busy lives at the Islamic Boarding School Darul Ulum Widang - Tuban, lacked interest in learning English, and did not have English manuals or other than textbooks from school. This service activity aims to improve the students' English through training at the Islamic Boarding School Darul Ulum Widang - Tuban. The method used in this service activity is fun training in the form of games, singing, and short conversations. The result of this service is that the students' English skills have increased with this training as evidenced by the increase in the average score of the students' English from 31.66 on the initial test to 65.83 on the final test, it can be concluded that using the training method is an effective way to improve Students' English at Islamic Boarding School Darul Ulum Widang - Tuban.
Liquid Organic Fertilizer Waste Painage Skin on Tomato Growth and Production in Alluvial Soil
Authors: Ciptono Eko Bahtiyar , Ramtalungi Yoshep , Pragustavi Lukman
Published: August 2022

This study aims to obtain a concentration of POC of pineapple skin waste that can provide the best growth and yield of tomatoes in alluvial soils. The research was carried   out from December 1, 2, 2019 to March 05, 2020 at the location located on Jalan Silat Baru, untan komplek. Pontianak City.  The study used the Complete Randomized Design (RAL) method with one factor, which consisted of 5 treatments with 5 tests and each test consisted of 4 sample plants. The treatment in question is k1 = 10% POC pineapple skin waste, k2 = 15% POC pineapple skin waste, k3= 20% POC pineapple skin waste, k4 = 25% POC pineapple skin waste, k5 = 30% POC pineapple skin waste. The variables observed in this study were plant height, root volume, dry weight of plants, Number of Fruits Per plant, Fruit Weight Per Plant, and Weight Per Fruit.  Based on the results of the study, it can be concluded that the application of POC pineapple skin waste with a concentration of 15% and 20% shows good growth at plant height 1 and 2 weeks after planting.  Based on the results of the study, it can be concluded that from the administration of PINEAPPLE SKIN WASTE POC, it is not found that the best concentration but an efficient concentration for tomato growth and yield is 10% POC of pineapple skin waste.
MURDER Using Learning to Improve Understanding Motivation and Learning Ability
Authors: Lilawati Emi , Wardani Dian Kusuma , Aini Alfi Qurrota
Published: August 2022

This study aims to determine the influence of Murder (cooperative) learning on learning outcomes reviewed from students' learning understanding and motivation. This study uses quantitative method with a type of questionnaire involving students of grade X SMK PGRI 2 Jombang with a population of 322 students, with a sample of 76 students randomly selected, data retrieval using questionnaires as data collection to find out how MURDER learning can motivate students. The results showed that the validity test results that have been conducted in this study showed that all questionnaire items (X1) were valid with a total score of Sig. greater than 0.227 and person correlation was positive. The results of the reliability test were then compared with the table r in this study N=76 and dk = 76 – 2 =74 with a significant level of 5% so that the table r value = 0.227. If r calculates ≥ r table then reliable question items, From the SPSS output results it appears that the significant value in the questionnaire 0.002 > .01 so it can be said that the data spread following the spread normal, and Hypothesis Test in this study shows that Murder learning has an effect on student learning.
Developing Instructional Media Based on ICT for Fourth Grade Students
Authors: Afidah Nurul , Kristanti Oktavia Ayu , Hanifah Hanifah
Published: August 2022

ABSTRACT

The aim of this study is to develop ‘English Fun’ in English instruction  for  fourth grade students of MI Al Hidayah Pagotan Jombang. This product focused on some vocabularies such as fruit, part of body, vegetables, and animals. The researcher chooses the ADDIE model in developing the product. This model consists of five steps. Those are: (1) analyze, (2) design, (3) development, (4) implementation, and (5) evaluation.on develop phase,  validation sheet was used to evaluate the quality of English Fun that was developed. Based on the data from the material expert validation sheet instrument above, the average of the overall aspect was 94% which means this product was “very good" and deserves to be implemented. The following were the validation results from media experts. Based on the data from the media expert validation sheet instrument above, the average of the whole aspect was 89% which mean this product was “very good” and feasible to be implemented. Based on the results of implementation with 10 students as a respondent, the result was 67% which mean that the results of the implementation were included in "good" which mean this instructional media can be used as a means of learning media to help students in learning activities
РИНОК КАВИ В УКРАЇНІ: ТЕНДЕНЦІЇ ТА ПЕРСПЕКТИВИ
Authors: Воробйов Костянтин , Гуржій Наталія
Published: August 2022

У статті проаналізовано динаміку середніх цін на зелене зерно Арабіки та Робусти та динаміку імпорту зеленого кавового зерна у світі з 2016 по 2020 рік. Розглянуто структуру експорту та імпорту кави в Україні за 2020 рік, визначено питому вагу кожної із підгруп кави. За базисним та ланцюговим методами розрахунку темпів приросту проаналізовано динаміку експорту та імпорту кави в Україні з 2016 по 2020 рік. Визначено ключових країн-партнерів України з імпорту та експорту кави з 2018 по 2020 р. Розглянуто та проаналізовано динаміку експорту та імпорту кави в Україні з 2016 по 2020 р. Проаналізовано обсяги товарообігу підприємств роздрібної торгівлі у фактичних та співставних цінах за 2016-2020 рр. Визначено частки продажів підприємствами роздрібної торгівлі кавою, що вироблена на території України з 2016 по 2020 рік. Окреслено тенденції розвитку українського ринку кави та його перспективи. На основі отриманих результатів проведеного дослідження зроблено висновок, що ринок кави в Україні поділений між світовими та національними товаровиробниками. Незважаючи на досить значну конкуренцію, український ринок кави зберігає можливості свого розвитку, зберігає стійкість і можливість для нарощування свого потенціалу. Також, було визначено перспективи подальших досліджень у даному напрямі.
ОЦІНКА ДОСТОВІРНОСТІ ІНФОРМАЦІЇ У ФІНАНСОВІЙ ЗВІТНОСТІ ПІДПРИЄМСТВА НА ОСНОВІ МОДЕЛЕЙ ДЖ. МОНТЬЄ, М. Д. БЕНІША ТА М. Л. РОКСАС
Authors: Артюх-Пасюта Олена , Мілька Алла
Published: August 2022

У статті проведено оцінку достовірності інформації у фінансовій звітності ПрАТ «Моршинський завод мінеральних вод «Оскар» за 2016-2020 рр. на основі моделі Дж. Монтьє (C-Score), моделі М. Д. Беніша (M-Score (8 variable) та моделі М. Л. Роксас (M-Score (5 variable). Запропоновано для оцінки достовірності інформації у фінансовій звітності вітчизняних суб’єктів господарювання різних форм і видів діяльності використовувати модель М. Д. Беніша (8 variable) та М. Л. Роксас (5 variable) на основі вивчення сутності, порядку застосування та обґрунтування їх переваг (відносна простота застосування, потенціал прогнозування, широта використання). Уточнено алгоритм розрахунку показників моделі Дж. Монтьє (C-Score), моделі М. Д. Беніша ( M-Score (8 variable) та моделі М. Л. Роксас (M-Score (5 variable) відповідно до затверджених в Україні форм фінансової звітності, що дозволить визначити рівень достовірності звітної інформації.
Gastroesophageal reflux in children with recurrent and chronic respiratory diseases: non-acid or acid?
Authors: Nguyen Van Bich
Published: August 2022

In some cases, gastroesophageal reflux (GER) may be accompanied by duodenogastric reflux, forming non-acid reflux, which has a certain influence on the clinical presentation and the response to anti-reflux therapy. The study aimed to determine the role of non-acid reflux in children with recurrent and chronic respiratory diseases (RCRD).

All children with RCRD, for unknown reason, poorly responding to respiratory-specific therapy, hospitalized for gastroesophageal reflux disease (GERD) screening, using dual pH-multichannel intraluminal impedance (pH-MII).

The study was conducted in 42 children at the age Me – 2.75; IQR 1.08-9.42. The most common type of reflux was weakly acid reflux - 62.25 [36.425-121.225], then acid - 34.05 [12.875-71.65], alkaline - 1.75 [0 - 12.375] episodes per day (p <0.05). Non-acid reflux was more common in children with only respiratory symptoms - no esophageal manifestations of GERD. All types of refluxes were more often recorded in the upright compared to the supine position. In 70% patients, cough could be associated with reflux, while in 88% children reflux was non-acid (including 69% - weakly acid, 19% - alkaline), in 38% - acid.

Non-acid reflux is the main type of GER in children with RCRD refractory to standard therapy, which could be associated with cough in this patient population.
CHROMagarTM Strep B for detecting group B Streptococcus in pregnant women at 35th to 37th of gestation
Authors: Nguyen Anh Thi Truc , Nguyen Loc Tran Mai , Tran Ngoc Bich
Published: August 2022

Group B Streptococcus (GBS) is one of the common causes of neonatal sepsis spreading from mothers to newborns. A common method to isolate and identify GBS is using Blood agar which delivers results in at least 48 hours. Although chromogenic culture media including CHROMagarTM StrepB, can develop colored colonies for detecting pathogenic bacteria easily, there has not been approached GBS isolation in Vietnam. This study was conducted to find out the GBS infection ratio in pregnant women at the 35th – 37th week of gestation. Furthermore, this research evaluates the efficacy of CHROMagarTM StrepB media and Blood agar in GBS detection as well.

In a cross-sectional survey, a total of 258 pregnant women at 35th to 37th of gestation screened for GBS at Thuan Kieu General Clinic from 04/2021 to 12/2021 were recruited. Rectovaginal swabs from these patients were cultured on Blood agar and CHROMagarTM StrepB. We performed data analysis using SPSS ver 20, p<0.05 was statistically significant.

Overall, out of 258 participants, 52 (20.16%) were GBS carriers. CHROMagarTM StrepB has significantly higher sensitivity than blood agar if spending a similar time (1.52 fold, p-value < 0.001), or event training a shortened time (18 hours and 48 hours), CHROMagarTM StrepB media is still more sensitive than blood agar (1.16 fold, p-value 0.044).

In this study, the GBS infection ratio in pregnant women at 35-37 weeks of gestation at Thuan Kieu General Clinic is 20.16%. Culturing vaginal-rectal specimens on CHROMagarTM StrepB medium is higher sensitivity and rapidly than blood agar for GBS detection. CHROMagarTM StrepB should be used to get more effective in identifying GBS carriers in near-term pregnant women.
Macroporous Sorbents for Adsorptive Removal of Metals, Sulfur and Non-Volatile Components from Oil Residues
Authors:   All-Russian Research Institute of Oil Refining, Iuzmukhametova R. F. ,   Gubkin University, Shmelkova O. I. ,   All-Russian Research Institute of Oil Refining, Boldushevskii R. E. ,   All-Russian Research Institute of Oil Refining, Khamzin Yu. A. ,   All-Russian Research Institute of Oil Refining, Shipitcyna A. A. ,   All-Russian Research Institute of Oil Refining, Antonov S. A. ,   All-Russian Research Institute of Oil Refining,   Gubkin University, Nikulshin P. A. ,   All-Russian Research Institute of Oil Refining,   Gubkin University
Published: August 2022

Upgrading of oil residues by adsorption techniques without hydrogen using macroporous large-granular adsorbents with high mechanical strength, a small surface area and a large volume of macropores, modified with various additives,has been studied. To obtain a macroporous structure, templates were tested - guar gum and wax emulsion. Both templates showed high efficiency; however, the use of wax makes it possible to obtain adsorbents with a larger pore volume. The processof adsorptive purification of feed based on the cracked residue of visbreaking provided a reduction of heavy metals content by 98%, while conversion of the residue boiling above 540°C was 75%. Adsorption treatment on a grained adsorbent can be used to obtain feedstock for a hydrotreating process aimed at obtaining both low-sulphur marine fuel and catalytic cracking feedstock.
The contemporary management of peritoneal metastasis: A journey from the cold past of treatment futility to a warm present and a bright future
Authors: Foster Jason M. , Zhang Chunmeng , Rehman Shahyan , Sharma Prateek , Alexander H. Richard
Published: August 2022

Peritoneal metastasis (PM) is often regarded as a less frequent pattern of spread; however, collectively across all spectra of primary tumors, the consequences of PM impact a large population of patients annually. Unlike other modes of metastasis, symptoms at presentation or during the treatment course are common, representing an additional challenge in the management of PM. Early efforts with chemotherapy and incomplete surgical interventions transiently improved symptoms, but durable symptom control and survival extension were rare, which established a perspective of treatment futility for PM through most of the 20th century. Notably, the continued development of better systemic therapy combinations, optimization of cytoreductive surgery (CRS), and rigorous investigation of combining regional therapy—specifically hyperthermic intraperitoneal chemotherapy—with CRS, have resulted in more effective multimodal treatment options for patients with PM. In this article, the authors provide a comprehensive review of the data establishing the contemporary approach for tumors with a high frequency of PM, including appendix, colorectal, mesothelioma, and gastric cancers. The authors also explore the emerging role of adding hyperthermic intraperitoneal chemotherapy to the well established paradigm of CRS and systemic therapy for advanced ovarian cancer, as well as the recent clinical trials identifying the efficacy of poly(adenosine diphosphate ribose) polymerase maintenance therapy. Finally, recent data are included that explore the role of precision medicine technology in PM management that, in the future, may help further improve patient selection, identify the best systemic therapy regimens, detect actionable mutations, and identify new targets for drug development.
Критерии разработки эффективных неорганических замедлителей горения для нетканых тонковолокнистых полиэфирных материалов
Authors: Назарович Андрей Николаевич , Рева Ольга Владимировна
Published: August 2022

Цель. Выявление важнейших критериев эффективности неорганических замедлителей горения по отношению к объемным полиэфирным материалам и особенностей термоокислительной деструкции модифицированных ими полиэфирных теплоизоляционных материалов.
Методы. Теоретический метод сравнительного анализа, экспериментальные методы гравиметрии, просвечивающей электронной микроскопии, дифференциально-сканирующей калориметрии, ГОСТированные огневые испытания.
Результаты. Исследовано влияние химического и гранулометрического состава аммонийно-фосфатных замедлителей горения на эффективность поверхностной огнезащиты и закономерности термоокислительной деструкции модифицированных ими полиэфирных волокнистых материалов. Доказано, что наиболее эффективны коллоидные системы с размерами частиц не более 50 нм, содержащие компоненты как газофазного, так и твердофазного действия. Сформулированы принципы разработки синтетических неорганических замедлителей горения для тонковолокнистых полимерных материалов.
Область применения исследований. Полученные результаты являются основой целенаправленного синтеза новых нетоксичных замедлителей горения для тонковолокнистых полиэфирных материалов различного назначения, в том числе строительных утеплителей и звукоизоляторов.
Особенности методологии расследования пожаров на легковых автомобилях
Authors: Пасовец Владимир Николаевич , Ковтун Вадим Анатольевич , Горошко Елена Юрьевна , Тагиев Шамхал Шахин
Published: August 2022

Цель. Совершенствование методики расследования пожаров на автотранспортных средствах.
Методы. Теоретический анализ, обобщение, систематизация.
Результаты. Статья посвящена расследованию дел о пожарах на легковых автомобилях. С учетом современных тенденций развития криминалистической тактики описаны этапы осмотра транспортных средств при поджогах, особенности работы с вещественными доказательствами, средства, приемы и методы обнаружения и изъятия следов.
Область применения исследований. Представленные результаты могут быть использованы в правоприменительной деятельности при расследовании пожаров на автотранспортных средствах.
Mídias sociais e práticas de luto online: uma revisão integrativa
Authors: Gomes Janete Monteiro , Oliveira Júnior Jesuino Santana de , Carneiro Maria Tereza Lemes Moreira
Published: August 2022

O processo de luto caracteriza-se como um fenômeno incompreendido e é ainda mais complicado quando nas interseções da vida urbana em um público em rede. Nesse contexto o objetivo do presente estudo foi buscar na literatura de forma integrativa autores que enfatizaram o luto e as redes sociais. Trata-se de um estudo de revisão integrativa de literatura com abordagem qualitativa onde durante a busca, encontrou-se um total de 361 resumos distribuídos de forma diferenciada em relação às bases de dados onde foram eleitos 11 artigos para leitura e estudo na íntegra, como resultados da presente revisão em que foi verificado que os métodos utilizados pelos artigos estudados, para poder diferenciar as mais variadas formas de evidência a serem discutidas. Dessa forma este estudo sobre o luto e o uso de mídia social continua a aumentar nossa base de conhecimento sobre o luto que afeta a experiência de diversas pessoas.
Noninvasive intracranial pressure in patients with traumatic brain injury
Authors: Link Caroline , Botelho Ana Flávia , Dhaese Thomas Markus , Frigieri Gustavo , Vellosa José Carlos Rebuglio , Welling Leonardo Christiaan
Published: August 2022

Monitoring and treatment of intracranial pressure are extremely important procedures in the management of patients with traumatic brain injury. The monitoring methods currently marketed are invasive and are not suitable for all patients. In addition to the risks offered, they are not available on all services. This study aims to describe the cases of five patients with traumatic brain injury of different severity who underwent noninvasive monitoring of intracranial pressure in the acute phase of the injury, relating the changes identified with the clinical picture presented. Patients showed important changes in intracranial pressure wave morphology, possibly related to the lesions, clinical presentation and therapeutic interventions used.
Motivação corporativa: um estudo em empresas do setor turístico na cidade de Carnaubal – Ceará
Authors: Nascimento Samara Rodrigues do , Pimenta Alcineide Aguiar , Reinaldo Felipe Alves , Lima Taísa Maria Gomes de , Aguiar Talita Souza , Bastos Francisca Flávia Freire , Albuquerque Anderson Terceiro de
Published: August 2022

O objetivo do estudo é analisar os fatores motivacionais aplicados ao setor turístico de Carnaubal – Ceará. Procedimentos metodológicos: Estudo qualitativo, realizado por meio de aplicação de entrevistas semiestruturadas para com os empregados e empregadores. Resultados: Percebeu-se que na visão dos empregadores os fatores motivacionais para o funcionário geram impactos perceptíveis para a empresa, assegurando que o funcionário motivado influencia no desenvolvimento da organização. Com base nas respostas dadas pelos empregados, percebeu-se que eles têm um conhecimento e entendimento médio sobre a importância da motivação do funcionário no ambiente de trabalho. Conclusão: Os funcionários de ambas as empresas têm uma visão limitada ao se tratar de motivação organizacional, mas ainda há confusão em correlacionar seu nível de motivação as suas atividades realizadas.
Recursos digitais como instrumentos didáticos: utilização do Mentimeter para uma aula interativa
Authors: Morais Roberta Alves de , Reis Deyse Almeida dos
Published: August 2022

A presente pesquisa possui como tema central a proposta de metodologias ativas na Educação Básica, a partir da utilização de recursos digitais como instrumentos didáticos, tomando como alvo de aplicação prática do estudo uma turma do terceiro ano do Ensino Médio da instituição de ensino Colégio Estadual Higino da Silveira, localizada na cidade de Teresópolis/RJ. O objetivo dessa pesquisa está na proposição de uma metodologia didática que se diferencie das práticas tradicionais de ensino, a fim de promover mais interação entre os discentes e o docente, através da ferramenta Mentimeter. Para tal, sua metodologia se baseia em um levantamento bibliográfico acerca dos temas que abrangem o ensino e os estilos de aprendizagem, bem como a inserção das tecnologias na educação, seguido por sua justaposição às atividades práticas para realização de uma análise final considerando a funcionalidade e eficácia da estratégia didática proposta na produção de melhores resultados no processo de ensino-aprendizagem.
Análise das características intervenientes do ambiente de prática do enfermeiro no espaço do hospital
Authors: Maciel Kamilla Rodrigues Leite , Ribeiro Antônio César , Souza Matheus Ricardo Cruz
Published: August 2022

Objetivo: Analisar a associação entre o ambiente das práticas e as características sociodemográficas e profissionais entre enfermeiros. Método: estudo com delineamento transversal, analítico, abordagem quantitativa, em um hospital público. A população foi constituída pelos profissionais enfermeiros. Para investigar as características intervenientes no ambiente de prática utilizamos o instrumento Practice Environment Scale, adaptado e validado para a cultura brasileira. Resultados: Participaram do estudo 103 (88,04%) profissionais enfermeiros. Os dados revelaram que 62,14% dos profissionais enfermeiros perceberam seu ambiente de prática profissional como desfavorável. Identificando-se correlação com as variáveis: estado civil, natureza do vínculo, natureza da função, unidade de lotação e tempo de trabalho na instituição. Conclusões: Aumentar as evidências sobre o reflexo dos ambientes desfavoráveis para a prática profissional da enfermagem resultará na melhoria da qualidade do trabalho ao tempo em que proporcionará condições aos gestores de planejamento e implementação de programas que visem ambientes de trabalho favoráveis à prática profissional.
IMPLEMENTATION OF VALUE STREAM MAPPING TO REDUCE WASTE IN WARRANTY CLAIM PROCESS AT COMMERCIAL VEHICLE AUTOMOTIVE COMPANY
Authors: Nur Maulana Sokheh , Amrina Uly
Published: August 2022

In the automotive industry, after-sales service becomes one of the marketing strategies used. The obstacles arose when there was a problem with the products, but the services related follow-up decisions problem report from customers seems too long because the information delivered by the dealer has not been fulfilled. This research aims to identify waste and implement improvements that can reach the standard after-sales service time set by the company. This study uses the value stream mapping (VSM) method combined with a root cause analysis approach to reduce waste. The problem identification found that the most prolonged decision was the starting system. Then, the dominant waste is a waiting process. The VSM improved processing time efficiency by 34.47% or 33.97 hours (1.4 days). This result proved that the overall reporting time reached 60 hours (2 days) as the company target.
OPTIMIZATION OF LASER CUTTING ENGRAVING PERFORMANCE WITH ACRYLIC MATERIAL USING THE TAGUCHI METHOD APPROACH
Authors: Buwono Bagas Jaya , Martana Budhi , Lukmana Muhammad Arifudin
Published: August 2022

Today's laser cutting machining process is often utilized in large industries as well as individual and student scientific projects. Acrylic is one of the materials whose processing involves a lot of laser cutting, but currently many laser cutting, especially low power ones, are not optimally optimized. In this study, the author wants to optimize laser cutting with 6.5 Watt power using the Taguchi optimization method on solid black acrylic material with a thickness of 3 mm, with reference to the surface roughness value of the workpiece after being subjected to the laser cutting process using the Ra unit. The control factors included are laser distance, laser power, cutting speed and cooling time. The experimental process was carried out 27 times with replication of measurements 2 times. The best result from the experiment was the roughness measurement value of 0.782 µm while the mean roughness value was 2.271 µm. After conducting the experiment, it is known that the best results are obtained with a laser distance factor of 20.6mm, cutting speed of 70 mm/min, laser power of 6.5 watts and cooling time of 10 s. Meanwhile, the effect of factors on the surface roughness results is the laser distance 27%, cutting speed 40.9%, laser power 18.9% and cooling time 7.05%. After calibrating the laser cutting, the cutting accuracy increased from ± 1mm to ± 0.4 mm or an increase of 60%, with an average final dimension measurement of 24.87 mm.
PENGARUH MODEL PROBLEM BASED LEARNING TERHADAP HASIL BELAJAR SUBTEMA MANUSIA DAN BENDA DI LINGKUNGANNYA
Authors: Marwah Hilda Sovia , Suchyadi Yudhie , Mahajani Tri
Published: August 2022

THE EFFECT OF PROBLEM BASED LEARNING MODEL ON LEARNING OUTCOMES OF HUMANS AND OBJECTS IN THEIR ENVIRONMENTThis research aims to determine the effect of the Problem Based Learning Model on Learning Outcomes of the Human and Objects Subtheme in their Environment in class V of SDN Duta Pakuan Bogor City for the 2020/2021 academic year. This study uses a quantitative research method through a two-group design quasi-experimental approach with Simple Random Sampling. The analytical technique used is the analysis prerequisite test which includes normality test, homogeneity test of variance, and hypothesis testing using t test. The results of the study show that there is an effect of the Problem Based Learning Model on the Learning Outcomes of Humans and Objects in their Environment. This can be seen from the N-Gain in the experimental class group of 82, while the control class group got an N-Gain value of 73. The completeness of learning outcomes obtained by the experimental group was 94% while in the control class group it was 77%. And the results of hypothesis testing that H0 is rejected and Ha is accepted because tcount (2,64697) ttable (2,00030). With this it can be concluded that the research has a positive and significant influence between "The Effect of Problem Based Learning Models on Learning Outcomes of Humans and Objects in their Environment". The results of this study are expected to provide new knowledge regarding the application of innovative learning models that can improve learning outcomes.
Consciousness and life after death in the evolution of intelligence
Authors: Senarath Dayathilake Kande Lekamalaya
Published: August 2022

To date, no scientific study has found evidence of an afterlife, and the mechanism of consciousness is two of the most challenging questions. Here, I show a hypothesis for consciousness and the probability of an afterlife through three simple thought experiments and theoretical evidence. The consciousness can be discussed based on a new theory that when a person or animal dies, the selection of a new nervous system's characteristic of a new life might depend on the characteristics of the final evolved yet unknown particle. Here, I suggest that the evolution of the said particle depends on the natural evolution of cognition. The fittest intellectuals survive happier; when a brain dies, the two microparticles might emit at infinite speed from the dead brain and simultaneously bond with a naturally select suitable zygote or early nervous system somewhere in the universe/s, forming a new life with the impact of new nurture.
Development of a simple mechanical measurement method to measure spasticity based on an analysis of a clinical maneuver and its concurrent validity with the modified Ashworth scale
Authors: Tanikawa Hiroki , Mukaino Masahiko , Itoh Shota , Kondoh Hikaru , Fujimura Kenta , Teranishi Toshio , Ohtsuka Kei , Hirano Satoshi , Kagaya Hitoshi , Saitoh Eiichi , Otaka Yohei
Published: August 2022

Background: Despite recent developments in the methodology for measuring spasticity, the discriminative capacity of clinically diagnosed spasticity has not been well established. This study aimed to develop a simple device for measuring velocity-dependent spasticity with improved discriminative capacity based on an analysis of clinical maneuver and to examine its reliability and validity.

Methods: This study consisted of three experiments. First, to determine the appropriate motion of a mechanical device for the measurement of velocity-dependent spasticity, the movement pattern and the angular velocity used by clinicians to evaluate velocity-dependent spasticity were investigated. Analysis of the procedures performed by six physical therapists to evaluate spasticity were conducted using an electrogoniometer. Second, a device for measuring the resistance force against ankle dorsiflexion was developed based on the results of the first experiment. Additionally, preliminary testing of validity, as compared to that of the Modified Ashworth Scale (MAS), was conducted on 17 healthy participants and 10 patients who had stroke with spasticity. Third, the reliability of the measurement and the concurrent validity of mechanical measurement in the best ankle velocity setting were further tested in a larger sample comprising 24 healthy participants and 32 patients with stroke.

Results: The average angular velocity used by physical therapists to assess spasticity was 268 ± 77°/s. A device that enabled the measurement of resistance force at velocities of 300°/s, 150°/s, 100°/s, and 5°/s was developed. In the measurement, an angular velocity of 300°/s was found to best distinguish patients with spasticity (MAS of 1+ and 2) from healthy individuals. A measurement of 300°/s in the larger sample differentiated the control group from the MAS 1, 1+, and 2 subgroups (p < 0.01), as well as the MAS 1 and 2 subgroups (p < 0.05). No fixed or proportional bias was observed in repeated measurements.

Conclusion: A simple mechanical measurement methodology was developed based on the analysis of the clinical maneuver for measuring spasticity and was shown to be valid in differentiating the existence and extent of spasticity. This study suggest possible requirements to improve the quality of the mechanical measurement of spasticity.
Mannose-decorated ginsenoside Rb1 albumin nanoparticles for targeted anti-inflammatory therapy
Authors: Fu Zhihui , Wang Xiaohui , Lu Xuan , Yang Ying , Zhao Lingling , Zhou Lin , Wang Kaikai , Fu Hanlin
Published: August 2022

Ginsenoside Rb1 is a potential anti-inflammatory natural molecule, but its therapeutic efficacy was tremendously hampered by the low solubility and non-targeted delivery. In this study, we innovatively developed a mannose (Man)-modified albumin bovine serum albumin carrier (Man-BSA) to overcome the previously mentioned dilemmas of Rb1. The constructed Man-BSA@Rb1 NPs could improve the solubility and increase the cellular uptake of Rb1, finally leading to the enhanced anti-inflammatory effects. The robust therapeutics of Man-BSA@Rb1 NPs were measured in terms of nitrite, tumor necrosis factor-α (TNF-α), and interleukin-6 (IL-6) levels, which might be achieved by potently inhibiting nuclear factor-κB (NF-κB) and mitogen-activated protein kinase (MAPK) signaling pathways in lipopolysaccharide (LPS)-induced Raw264.7 cells. Moreover, the therapeutic efficacy of Man-BSA@Rb1 NPs was further confirmed in the d-Gal/LPS-induced liver injury model. The results indicated that Man-BSA may offer a promising system to improve the anti-inflammatory therapy of Rb1.
Single-cell RNA sequencing reveals the cellular and molecular changes that contribute to the progression of lung adenocarcinoma
Authors: Liu Bing , Wang Chen , Fang Zhanjie , Bai Jing , Qian Ying , Ma Yuanyuan , Ruan Xiuyan , Yan Shi , Li Shaolei , Wang Yaqi , Dong Bin , Yang Xin , Li Meng , Xia Xuefeng , Qu Hongzhu , Fang Xiangdong , Wu Nan
Published: August 2022

Pure ground glass nodules (GGNs) and solid nodules (SNs) represent early and relatively late stages of lung adenocarcinoma (LUAD) in radiology, respectively. The cellular and molecular characteristics of pure GGNs and SNs have not been comprehensively elucidated. Additionally, the mechanism driving the progression of lung adenocarcinoma from pure GGN to SN in radiology is also elusive. In this study, by analyzing the single-cell transcriptomic profiles of 76,762 cells from four pure GGNs, four SNs, and four normal tissues, we found that anti-tumor immunity mediated by NK and CD8+T cells gradually weakened with the progression of LUAD and humoral immunity mediated by plasma B cells was more active in SNs. Additionally, the proliferation ability of some special epithelial cell increased during the progression process from pure GGN to SN. Furthermore, stromal cells and M2 macrophages could assist the progression of LUAD. Through comprehensive analyses, we revealed dynamic changes in cellular components and intercellular interactions during the progression of LUAD. These findings could facilitate our understanding of LUAD and discovery of novel therapeutic targets.
Synthesis, bioactivity, and molecular docking of novel arylpiperazine derivatives as potential AR antagonists
Authors: Qi Yueheng , Chen Hong , Chen Shijin , Shen Jianliang , Li Jingguo
Published: August 2022

Prostate cancer is one of the malignant tumors and the second most common malignant tumor in men. Clinically used androgen receptor (AR)–targeted drugs can antagonize androgen and inhibit tumor growth, but these drugs can cause serious resistance problems. To develop novel AR antagonists, 22 kinds of arylpiperazine derivatives were designed and synthesized, and the derivatives 5, 8, 12, 19, 21, 22, 25, and 26 not only showed strong antagonistic potency (>55% inhibition) and binding affinities (IC50 <3 μM) to AR, but also showed stronger inhibitory activity to LNCaP cells versus PC-3 cells. Among them, derivative 21 exhibited the highest binding affinity for AR (IC50 = 0.65 μM) and the highest antagonistic potency (76.2% inhibition). Docking studies suggested that the derivative 21 is primarily bound to the AR-LBP site by the hydrophobic interactions. Overall, those results provided experimental methods for developing novel arylpiperazine derivatives as potent AR antagonists.
Dual-functional SERRS and fluorescent aptamer sensor for abscisic acid detection via charged gold nanorods
Authors: Zhang Yanyan , Li Wei , Zhang Hao , Wang Shun , Li Xiaodong , Zaigham Abbas Naqvi Syed Muhammad , Hu Jiandong
Published: August 2022

Abscisic acid (ABA) is a plant hormone, which plays an important role in plant growth, crop cultivation and modern agricultural engineering management. Accordingly, the detection of ABA content combined with new techniques and methods has become a more and more popular problem in the field of agricultural engineering. In this work, a SERRS and fluorescence dual-function sensor based on the fluorescence quenching and Raman enhancement properties of gold nanorods (AuNRs) was developed, and applied to the detection of plant hormone ABA. The dual-function reporter molecule Rhodamine isothiocyanate (RBITC) and complementary DNA (cDNA) were modified on AuNRs (AuNRs@RBITC@cDNA) as signal probes and aptamer modified magnetic nanoparticles (Fe3O4MNPs@Apt) as capture probes. Through the specific recognition of ABA aptamer and its complementary chains, an dual-function aptamer sensor based on SERRS and fluorescence was constructed. When ABA molecules were present in the detection system, the signal probes were detached from the capture probes due to the preferential binding between aptamer and ABA molecules. SERS signal of the reporter molecules appeared in the supernatant after magnetic separation, and it increased with the increase of ABA concentration. If the etching agent that can etch AuNRs was added to the supernatant, the AuNRs was etching disappeared, then the signal molecules fall off from the AuNRs, and the fluorescence signal intensity would recovered. The intensity of fluorescence signal also increased with the increase of ABA concentration. Thus, the quantitative relationship between ABA concentration and SERRS intensity and fluorescence intensity of signal molecules was established. The linear range of SERRS detection was 100 fM–0.1 nM, the detection limit was 38 fM; The linear range of fluorescence detection was 1 pM–100 nM, the detection limit is 0.33 p.m. The constructed dual-effect sensor was used in the recovery laboratory of real ABA samples, the recovery rate was up to 85–108%.
Preparation and characterization of ZnO/graphene/graphene oxide/multi-walled carbon nanotube composite aerogels
Authors: Shen Yang , Yuan Zhihao , Cheng Fengjiao , Cui Zhen , Ma Deming , Bai Yueyue , Zhao Shuqing , Deng Jieyao , Li Enling
Published: August 2022

ZnO/Graphene (G)/Graphene Oxide (GO)/Multi-walled Carbon Nanotube (MCNT) composite aerogels with a three-dimensional porous structure were prepared by the sol-gel method under average temperature and alkaline conditions, combined with freeze-drying process and heat treatment process. The photocatalytic degradation of Rhodamine B (RhB) was mainly studied. The scanning electron microscope (SEM) test results showed that the morphology uniformity of the ZnO/G/GO/MCNT composite aerogel was significantly enhanced, which effectively solving the agglomeration problem of MCNT and ZnO. The photocatalytic degradation test results of RhB show that due to the synergistic effect of physical adsorption and photocatalytic degradation, the total degradation efficiency of RhB by ZnO/G/GO/MCNT could reach 86.8%, which is 3.3 times higher than that of ZnO. In addition, the synergistic effect of ZnO and G effectively hinders the recombination of photo-generated electron-hole pairs and enhances photocatalytic activity. The ZnO/G/GO/MCNT composite aerogel can be applied in the visible light catalytic degradation of water pollution.
The first apicoplast tRNA thiouridylase plays a vital role in the growth of Toxoplasma gondii
Authors: Yang Yimin , Lin Mi , Chen Xueqiu , Zhao XianFeng , Chen Lulu , Zhao Mingxiu , Yao Chaoqun , Sheng Kaiyin , Yang Yi , Ma Guangxu , Du Aifang
Published: August 2022

Toxoplasmosis caused by the protozoan Toxoplasma gondii is one of the most common parasitic diseases in humans and almost all warm-blooded animals. Lys, Glu, and Gln-specific tRNAs contain a super-modified 2-thiourea (s2U) derivatives at the position 34, which is essential for all living organisms by maintaining the structural stability and aminoacylation of tRNA, and the precision and efficiency of codon recognition during protein translation. However, the enzyme(s) involved in this modification in T. gondii remains elusive. In this report, three putative tRNA-specific 2-thiolation enzymes were identified, of which two were involved in the s2U34 modification of tRNALys, tRNAGlu, and tRNAGln. One was named TgMnmA, an apicoplast-located tRNA-specific 2-thiolation enzyme in T. gondii. Knockout of TgMnmA showed that this enzyme is important for the lytic cycle of tachyzoites. Loss of TgMnmA also led to abnormities in apicoplast biogenesis and severely disturbed apicoplast genomic transcription. Notably, mice survived from the infection with 10 TgMnmA-KO RH tachyzoites. These findings provide new insights into s2U34 tRNA modification in Apicomplexa, and suggest TgMnmA, the first apicoplast tRNA thiouridylase identified in all apicomplexans, as a potential drug target.