bluuebunny/crossref_metadata_2025 huggingface dataset:
Polarization-Independent Ultra-Wideband Metamaterial Absorber for Solar Harvesting at Infrared Regime
Authors: Alam Asraful , Islam Sikder Sunbeam , Islam Md. Hobaibul , Almutairi Ali F. , Islam Mohammad Tariqul
Published: June 2020

This paper presents an ultra-wideband metamaterial absorber for solar harvesting in the infrared regime (220–360 THz) of the solar spectrum. The proposed absorber consists of square-shaped copper patches of different sizes imposed on a GaAs (Gallium arsenide) substrate. The design and simulation of the unit cell are performed with finite integration technique (FIT)-based simulation software. Scattering parameters are retrieved during the simulation process. The constructed design offers absorbance above 90% within a 37.89% relative bandwidth and 99.99% absorption over a vast portion of the investigated frequency range. An equivalent circuit model is presented to endorse the validity of the proposed structure. The calculated result strongly agrees with the simulated result. Symmetrical construction of the proposed unit cell reports an angular insensitivity up to a 35° oblique incidence. Post-processed simulation data confirm that the design is polarization-insensitive.
A Two-Step Annealing Method to Enhance the Pyroelectric Properties of Mn:PIMNT Chips for Infrared Detectors
Authors: Zhu Rongfeng , Zhao Jing , Chen Jianwei , Fang Bijun , Xu Haiqing , Di Wenning , Jiao Jie , Wang Xi’an , Luo Haosu
Published: June 2020

Mn:0.15Pb(In1/2Nb1/2)O3-0.55Pb(Mg1/3Nb2/3)O3-0.30PbTiO3 (Mn:PIMNT) pyroelectric chips were prepared by a two-step annealing method. For the two steps, annealing temperatures dependence of microstructure, defects, surface stress, surface roughness, dielectric properties and pyroelectric properties were studied comprehensively. The controlling factors influencing the pyroelectric properties of the Mn:PIMNT crystals were analyzed and the optimum annealing temperature ranges for the two steps were determined: 600–700 °C for the first step and 500–600 °C for the second step. The pyroelectric properties of the thin Mn:PIMNT chips were significantly enhanced by the two-step annealing method via tuning oxygen vacancies and eliminating surface stress. Based on Mn:PIMNT pyroelectric chips annealed at the most favorable conditions (annealed at 600 °C for the first step and 500 °C for the second step), infrared detectors were prepared with specific detectivity D* = 1.63 × 109 cmHz1/2W−1, nearly three times higher than in commercial LiTaO3 detectors.
Extrusion-Based Additive Manufacturing with Carbon Reinforced Concrete: Concept and Feasibility Study
Authors: Mechtcherine Viktor , Michel Albert , Liebscher Marco , Schmeier Tobias
Published: June 2020

Additive manufacturing with cement-based materials needs sound approaches for the direct, seamless integration of reinforcement into structural and non-structural elements during their fabrication. Mineral-impregnated Carbon-Fibre (MCF) composites represent a new type of non-corrosive reinforcement that offers great potential in this regard. MCF not only exhibits high performance with respect to its mechanical characteristics and durability, but it also can be processed and shaped easily in the fresh state and, what is more, automated. This article describes different concepts for the continuous, fully automated integration of MCF reinforcement into 3D concrete printing based on layered extrusion. Moreover, for one of the approaches presented and discussed, namely 3D concrete printing with MCF supply from a continuous, stationary impregnation line and deposition of MCF between concrete filaments, a feasibility study was performed using a gantry 3D printer. Small-scale walls were printed and eventually used for the production of specimens for mechanical testing. Three-point bend tests performed on two different beam geometries showed a significant enhancement of both flexural strength and, more especially, deformability of the specimens reinforced with MCF in comparison to the specimens made of plain concrete.
Time-Varying Vector Norm and Lower and Upper Bounds on the Solutions of Uniformly Asymptotically Stable Linear Systems
Authors: Vrabel Robert
Published: June 2020

Based on the eigenvalue idea and the time-varying weighted vector norm in the state space R n we construct here the lower and upper bounds of the solutions of uniformly asymptotically stable linear systems. We generalize the known results for the linear time-invariant systems to the linear time-varying ones.
Averaging Methods for Second-Order Differential Equations and Their Application for Impact Systems
Authors: Fečkan Michal , Pačuta Július
Published: June 2020

In this paper, we discuss the averaging method for periodic systems of second order and the behavior of solutions that intersect a hyperplane. We prove an averaging theorem for impact systems. This allows us to investigate the approximate dynamics of mechanical systems, such as the weakly nonlinear and weakly periodically forced Duffing’s equation of a hard spring with an impact wall, or a weakly nonlinear and weakly periodically forced inverted pendulum with double impacts.
Purification and Characterization of a New CRISP-Related Protein from Scapharca broughtonii and Its Immunomodulatory Activity
Authors: Liu Wanying , Bi Sixue , Li Chunlei , Zheng Hang , Guo Zhongyi , Luo Yuanyuan , Ou Xiaozheng , Song Liyan , Zhu Jianhua , Yu Rongmin
Published: June 2020

More and more attention has been paid to bioactive compounds isolated from marine organisms or microorganisms in recent years. At the present study, a new protein coded as HPCG2, was purified from Scapharca broughtonii by stepwise chromatography methods. The molecular weight of HPCG2 was determined to be 30.71 kDa by MALDI-TOF-MS. The complete amino acid sequence of HPCG2 was obtained by tandem mass spectrometry combined with transcriptome database analysis, and its secondary structure was analyzed using circular dichroism. HPCG2 comprised 251 amino acids and contained 28.4% α-helix, 26% β-sheet, 18.6% β-turn, and 29.9% random coil. HPCG2 was predicted to be a cysteine-rich secretory protein-related (CRISP-related) protein by domain prediction. Moreover, HPCG2 was proved to possess the immunomodulatory effect on the murine immune cells. MTT assay showed that HPCG2 promoted the proliferation of splenic lymphocytes and the cytotoxicity of NK cells against YAC-1 cells. Flow cytometry test revealed that HPCG2 enhanced the phagocytic function of macrophages and polarized them into M1 type in RAW264.7 cells. In particular, Western blot analysis indicated that the immunomodulatory mechanism of HPCG2 was associated with the regulation on TLR4/JNK/ERK and STAT3 signaling pathways in RAW 264.7 cells. These results suggested that HPCG2 might be developed as a potential immunomodulatory agent or new functional product from marine organisms.
Circulating Irisin in Healthy Adults: Changes after Acute Exercise, Correlation with Body Composition, and Energy Expenditure Parameters in Cross-Sectional Study
Authors: Lagzdina Rudite , Rumaka Maija , Gersone Gita , Tretjakovs Peteris
Published: June 2020

Background and Objectives: Skeletal muscles are considered to be the main source of circulating irisin, both at rest and during physical activity. The aim of this study was to investigate the connection between irisin, body composition, and energy metabolism in humans. Materials and Methods: Serum irisin concentrations before and after acute aerobic exercise on a treadmill in 84 healthy adults were measured and their association with body composition and energy expenditure (EE) (obtained from indirect calorimetry) was determined. Results: The total pre-exercise irisin concentrations in males and females were similar, but higher in females when expressed per body mass kg (p < 0.001). There was an association between pre-exercise irisin per body mass kg, visceral fat rating (rho = −0.52, p = 0.001), and lean tissue % (rho = 0.41, p < 0.05) in males and lean body mass index (LBMI) (rho = −0.59, p < 0.001) in females. The pre-exercise irisin concentration correlated with the resting metabolic rate (RMR) in both sexes (rho = 0.44 in males, rho = 0.36 in females; p < 0.05), but with walking, running, and the EE difference from RMR in running (Δ running EE) in males only (rho = 0.32 to 0.37, p < 0.05). There was no significant change in irisin concentration after exercise in 58% of participants, while it decreased in 23%, and increased in 19%. In male subjects with no change in irisin concentration after exercise, running (p < 0.05) and Δ running EE per body mass kg (p < 0.05) were higher than in those with decreased irisin concentration. Conclusions: These findings indicate that the association of irisin concentration with body composition and EE parameters has sex-dependent differences, and acute exercise can lead to various changes in post-exercise irisin levels.
A Six-Year Analysis of Biological Therapy for Severe Psoriasis in a Lithuanian Reference Centre of Dermatovenereology
Authors: Raudonis Tadas , Gliebute Akvile , Grigaityte Anna Greta , Lukosiunaite Zivile , Karmaziene Tatjana , Grigaitiene Jurate
Published: June 2020

Background and Objectives: Biological therapy is widely used for the treatment of severe psoriasis. The objective of this study was to evaluate the efficacy and safety of biological therapy for patients with severe psoriasis. Materials and Methods: A retrospective study of 79 patients with severe psoriasis, who have been treated with biological therapy between 2012 and 2018, was conducted. During this study, the following data were collected and evaluated: sex, age, body mass index (BMI), duration of illness, the results of treatment with biological therapy, concomitant therapy, Psoriasis Area and Severity Index (PASI) and adverse events. Results: In total, 74.7% (n = 59) of subjects were male. Their overall average age was 47.4 ± 11.4 (range: 18–73) years. Their baseline BMI was 27.6 ± 5.9, which increased to 29.6 ± 4.5 after 6 years of treatment. The mean duration of psoriasis was 25.7 ± 12.5 years. In total, 39.2% (n = 31) of subjects received infliximab, 36.7% (n = 29)—etanercept, 24.1% (n = 19)—ustekinumab. The treatment duration for infliximab, etanercept and ustekinumab was 201.6 ± 86.8, 156.2 ± 137.4 and 219.1 ± 95.7 weeks (p < 0.01), respectively. Overall, 65.8% (n = 52) of subjects were also on methotrexate; 30.8% (n = 16) of them discontinued it due to clinical improvement (31.3% (n = 5)), impaired liver function (31.3% (n = 5)), and intolerance (25% (n = 4)). Baseline PASI was 20.8 ± 8.8. PASI 50 was achieved by 96.2% (n = 76) of patients at week 11, PASI 75 by 86.1% (n = 68) at week 16, PASI 90 by 54.4% (n = 43) at week 35, and PASI 100 by 13.9% (n = 11) at week 33. The overall incidence rate of adverse events was 0.362 per patient year of follow-up. Conclusion: Biological therapy is an effective and safe treatment for patients with severe psoriasis.
Combination of a Self-Regulation Module and Mobile Application to Enhance Treatment Outcome for Patients with Acne
Authors: Liu Yi-Shan , Lu Nan-Han , Shieh Po-Chuen , Sun Cheuk-Kwan
Published: June 2020

Background and Objectives: Acne, an inflammatory disorder of the pilosebaceous unit associated with both physiological and psychological morbidities, should be considered a chronic disease. The application of self-regulation theory and therapeutic patient education has been widely utilized in different health-related areas to help patient with a chronic disease to attain better behavioral modification. The present study aims at investigating the treatment efficacy of combining a self-regulation-based patient education module with mobile application in acne patients. Materials and Methods: This was one-grouped pretest–posttest design at a single tertiary referral center with the enrollment of 30 subjects diagnosed with acne vulgaris. Relevant information was collected before (week 0) and after (week 4) treatment in the present study, including the Acne Self-Regulation Inventory (ASRI), Cardiff Acne Disability Index (CADI), and Dermatology Life Quality Index (DLQI) that involved a questionnaire-based subjective evaluation of the patient’s ability in self-regulation and quality of life as well as clinical Acne Grading Scores (AGS) that objectively assessed changes in disease severity. To reinforce availability and feasibility, an individualized platform was accessible through mobile devices for real-time problem solving between hospital visits. Results: Thirty subjects completed the designed experiment. An analysis of the differences between scores of pretest and posttest of ASRI demonstrated substantial elevations (p < 0.001). The questionnaire survey of CADI and DLQI dropped significantly after the application of a self-regulation-based patient education module with a mobile application, revealing substantial reductions in both parameters (p < 0.001). The sign test demonstrated a remarkably significant difference in AGS (Z = −7.38, p < 0.001), indicating notable improvement in the clinical severity of acne after treatment. Conclusions: After incorporating modern mobile application, a self-regulation-based therapeutic patient education module could significantly improve treatment outcomes among acne patients.
Acute Disseminated Encephalomyelitis with Seizures and Myocarditis: A Fatal Triad
Authors: Lademann Hanne , Bertsche Astrid , Petzold Axel , Zack Fred , Büttner Andreas , Däbritz Jan , Hauenstein Christina , Bahn Erik , Spang Christian , Reuter Daniel , Warnke Philipp , Ehler Johannes
Published: June 2020

Autoimmune pathology of acute disseminated encephalomyelitis (ADEM) is generally restricted to the brain. Our objective is to expand the phenotype of ADEM. A four-year-old girl was admitted to the pediatric emergency room of a university medical center five days after a common upper respiratory tract infection. Acute symptoms were fever, leg pain, and headaches. She developed meningeal signs, and her level of consciousness dropped rapidly. Epileptic seizure activity started, and she became comatose, requiring intubation and mechanical ventilation. Serial brain magnetic resonance imaging (MRI) illustrated the fulminant development of ADEM. Treatment escalation with high-dose corticosteroids, immunoglobulins, and plasma exchange did not lead to clinical improvement. On day ten, the patient developed treatment-refractory cardiogenic shock and passed away. The postmortem assessment confirmed ADEM and revealed acute lymphocytic myocarditis, likely explaining the acute cardiac failure. Human metapneumovirus and picornavirus were detected in the tracheal secrete by PCR. Data sources–medical chart of the patient. This case is consistent with evidence from experimental findings of an association of ADEM with myocarditis as a postinfectious systemic autoimmune response, with life-threatening involvement of the brain and heart.
Surface Modification of Porous Titanium Discs Using Femtosecond Laser Structuring
Authors: Rodríguez Ángel , Trueba Paloma , Amado José Manuel , Tobar María José , Giner Mercè , Amigó Vicente , Torres Yadir
Published: June 2020

The failure of titanium implants is associated with two main problems that include the bone resorption and fracture of the surrounding bone tissue (stiffness incompatibility) and implant loosening (poor osseointegration). The development of porous titanium implants with low Young modulus solve the stress shielding phenomenon, while the modification of the implant surface must be implemented to promote a fast bond between the implant and bone. In this work, femtosecond laser micromachining was applied to modify the topography of the surface of Ti porous samples obtained by a space-holder technique to obtain hierarchical structures (micro and nano roughness patterns) to enhance osseointegration. Scanning electron microscopy, confocal laser microscopy, and image analysis were used for characterization of the surface morphology, roughness, and porosity before and after performing the laser treatment. Based on these results, the effect of the treatment on the mechanical behavior of the samples was estimated. In addition, a preliminary in-vitro test was performed to verify the adhesion of osteoblasts (filopodia presence) on modified titanium surface. Results revealed that laser texturing generated clusters of micro-holes and micro-columns both on the flat surface of the samples and inside the macro-pores, and periodic nanometric structures across the entire surface. The porous substrate offers suitable biomechanics (stiffness and yield strength) and bio-functional behavior (bone ingrowth and osseointegration), which improves the clinic success of titanium implants.
Inactivation of the sfgtr4 Gene of Shigella flexneri Induces Biofilm Formation and Affects Bacterial Pathogenicity
Authors: Kaoukab-Raji Abdelmoughit , Biskri Latéfa , Allaoui Abdelmounaaïm
Published: June 2020

Biofilm formation is a significant cause for the environmental persistence of foodborne pathogens. This phenomenon remains misunderstood in Shigella flexneri whose pathogenicity is mainly associated with the virulence plasmid pWR100. Sequence analysis of the latter predicts a putative lipopolysaccharides (LPS) glycosyltransferase (Gtr) encoded by Sfgtr4, which is the second gene of the SfpgdA-orf186-virK-msbB2 locus. We demonstrated here that purified SfGtr4 exhibited a Gtr activity in vitro by transferring glucose to lipid A. To establish the role of SfGtr4 in virulence, we generated a Sfgtr4 mutant and assessed its phenotype in vitro. Sfgtr4 mutant significantly reduced HeLa cells invasion without impairing type III effectors secretion, increased susceptibility to lysozyme degradation, and enhanced bacterial killing by polymorphonuclear neutrophils (PMNs). SfGtr4 is related to proteins required in biofilm formation. We established conditions whereby wild-type Shigella formed biofilm and revealed that its appearance was accelerated by the Sfgtr4 mutant. Additional phenotypical analysis revealed that single SfpdgA and double SfpgdA-Sfgtr4 mutants behaved similarly to Sfgtr4 mutant. Furthermore, a molecular interaction between SfGtr4 and SfPgdA was identified. In summary, the dual contribution of SfGtr4 and SfPgdA to the pathogenicity and the regulation biofilm formation by S. flexneri was demonstrated here.
Transcriptome Profiling of Toxoplasma gondii-Infected Human Cerebromicrovascular Endothelial Cell Response to Treatment with Monensin
Authors: Harun Mohammad S. R. , Taylor Mica , Zhu Xing-Quan , Elsheikha Hany M.
Published: June 2020

Central to the progression of cerebral toxoplasmosis is the interaction of Toxoplasma gondii with the blood-brain barrier (BBB) endothelial cells. In the present work, we tested the hypothesis that inhibition of Wnt pathway signalling by the monovalent ionophore monensin reduces the growth of T. gondii infecting human brain microvascular endothelial cells (hBMECs) or microglial cells. The anti-parasitic effect of monensin (a Wnt signalling inhibitor) on the in vitro growth of T. gondii tachyzoites was investigated using two methods (Sulforhodamine B staining and microscopic parasite counting). The monensin inhibited T. gondii growth (50% inhibitory concentration [IC50] = 0.61 μM) with a selective index = 8.48 when tested against hBMECs (50% cytotoxic concentration [CC50] = 5.17 μM). However, IC50 of monensin was 4.13 μM with a SI = 13.82 when tested against microglia cells (CC50 = 57.08 μM), suggesting less sensitivity of microglia cells to monensin treatment. The effect of T. gondii on the integrity of the BBB was assessed by the transendothelial electrical resistance (TEER) assay using an in vitro human BBB model. The results showed that T. gondii infection significantly decreased hBMECs’ TEER resistance, which was rescued when cells were treated with 0.1 µM monensin, probably due to the anti-parasitic activity of monensin. We also investigated the host-targeted effects of 0.1 µM monensin on global gene expression in hBMECs with or without T. gondii infection. Treatment of hBMECs with monensin did not significantly influence the expression of genes involved in the Wnt signalling pathway, suggesting that although inhibition of the Wnt signalling pathway did not play a significant role in T. gondii infection of hBMECs, monensin was still effective in limiting the growth of T. gondii. On the contrary, monensin treatment downregulated pathways related to steroids, cholesterol and protein biosynthesis and their transport between endoplasmic reticulum and Golgi apparatus, and deregulated pathways related to cell cycle and DNA synthesis and repair mechanisms. These results provide new insight into the host-modulatory effect of monensin during T. gondii infection, which merits further investigation.
Anti-Inflammatory and Gut Microbiota Modulatory Effect of Lactobacillus rhamnosus Strain LDTM 7511 in a Dextran Sulfate Sodium-Induced Colitis Murine Model
Authors: Yeo Soyoung , Park Hyunjoon , Seo Eunsol , Kim Jihee , Kim Byoung Kook , Choi In Suk , Huh Chul Sung
Published: June 2020

Inflammatory bowel disease (IBD) is a group of conditions involving chronic relapsing-remitting inflammation of the gastrointestinal tract with an unknown etiology. Although the cause–effect relationship between gut microbiota and IBD has not been clearly established, emerging evidence from experimental models supports the idea that gut microbes play a fundamental role in the pathogenesis of IBD. As microbiome-based therapeutics for IBD, the beneficial effects of probiotics have been found in animal colitis models and IBD patients. In this study, based on the dextran sulfate sodium (DSS)-induced colitis mouse model, we investigated Lactobacillus rhamnosus strain LDTM 7511 originating from Korean infant feces as a putative probiotic strain for IBD. The strain LDTM 7511 not only alleviated the release of inflammatory mediators, but also induced the transition of gut microbiota from dysbiotic conditions, exhibiting the opposite pattern in the abundance of DSS colitis-associated bacterial taxa to the DSS group. Our findings suggest that the strain LDTM 7511 has the potential to be used as a probiotic treatment for IBD patients in comparison to L. rhamnosus GG (ATCC 53103), which has been frequently used for IBD studies.
In vivo Fitness of Acinetobacter baumannii Strains in Murine Infection Is Associated with International Lineage II-rep-2 and International Lineage III Clones Showing High Case Fatality Rates in Human Infections
Authors: Nutman Amir , Lellouche Jonathan , Lifshitz Ziv , Glick Rivka , Carmeli Yehuda
Published: June 2020

We previously reported that the 14-day case fatality rate (CFR) in patients with carbapenem-resistant Acinetobacter baumannii (CRAB) bacteremia varied between infecting clones. Here, we evaluated the in vitro and in vivo fitness of CRAB blood isolates belonging to clones with low CFR (< 32% 14-day mortality) and high CFR (65% 14-day mortality). Fitness was measured in vitro using a growth curve assay and in vivo using murine thigh muscle and septicemia models of infection. Our sample included 38 CRAB isolates belonging to two clones with low CFR (international lineage (IL)-II-rep-1, n = 13 and IL-79, n = 6) and two clones with high CFR (IL-III, n = 9 and IL-II-rep-2, n = 10). In in vitro growth curves, mean lag time, generation time and maximal growth varied between clones but could not discriminate between the high and low CFR clones. In the in vivo models, bacterial burdens were higher in mice infected with high CFR clones than in those infected with low CFR clones: in thigh muscle, 8.78 ± 0.25 vs. 7.53 ± 0.25 log10CFU/g, p < 0.001; in infected spleen, 5.53 ± 0.38 vs. 3.71 ± 0.35 log10CFU/g, p < 0.001. The thigh muscle and septicemia model results were closely correlated (r = 0.93, p < 0.01). These results suggest that in vivo but not in vitro fitness is associated with high CFR clones.
From Wuhan to COVID-19 Pandemic: An Up-to-Date Review of Its Pathogenesis, Potential Therapeutics, and Recent Advances
Authors: Zeouk Ikrame , Bekhti Khadija , Lorenzo-Morales Jacob
Published: June 2020

The emergence of a novel human coronavirus (SARS-CoV-2) causing severe contagious respiratory tract infections presents a serious threat to public health worldwide. To date, there are no specific antiviral agents available for this disease, currently known as COVID-19. Therefore, genomic sequencing and therapeutic clinical trials are being conducted to develop effective antiviral agents. Several reports have investigated FDA-approved drugs as well as in silico virtual screening approaches such as molecular docking and modeling to find novel antiviral agents. Until now, antiparasitic drugs such as chloroquine have shown the most relevant results. Furthermore, there is an urgent need to understand the pathogenesis of this novel coronavirus, its transmission routes, surface survival and evolution in the environment. So far, the scientific community has indicated a possible transmission of COVID-19 via blood transfusion which is challenging in the case of asymptomatic individuals. Protocols for pathogen inactivation are also needed. In this paper, we reviewed recent findings about this life-threatening pandemic.
Glutamine for Amelioration of Radiation and Chemotherapy Associated Mucositis during Cancer Therapy
Authors: Anderson Peter M. , Lalla Rajesh V.
Published: June 2020

Glutamine is a major dietary amino acid that is both a fuel and nitrogen donor for healing tissues damaged by chemotherapy and radiation. Evidence supports the benefit of oral (enteral) glutamine to reduce symptoms and improve and/or maintain quality of life of cancer patients. Benefits include not only better nutrition, but also decreased mucosal damage (mucositis, stomatitis, pharyngitis, esophagitis, and enteritis). Glutamine supplementation in a high protein diet (10 grams/day) + disaccharides, such as sucrose and/or trehalose, is a combination that increases glutamine uptake by mucosal cells. This increased topical effect can reduce painful mucosal symptoms and ulceration associated with chemotherapy and radiation in the head and neck region, esophagus, stomach and small intestine. Topical and oral glutamine seem to be the preferred routes for this amino acid to promote mucosal healing during and after cancer treatment.
Entomological Surveillance for Zika and Dengue Virus in Aedes Mosquitoes: Implications for Vector Control in Thailand
Authors: Kosoltanapiwat Nathamon , Tongshoob Jarinee , Singkhaimuk Preeraya , Nitatsukprasert Chanyapat , Davidson Silas A. , Ponlawat Alongkot
Published: June 2020

Entomological surveillance for arthropod-borne viruses is vital for monitoring vector-borne diseases and informing vector control programs. In this study, we conducted entomological surveillance in Zika virus endemic areas. In Thailand, it is standard protocol to perform mosquito control within 24 h of a reported dengue case. Aedes females were collected within 72 h of case reports from villages with recent Zika–human cases in Kamphaeng Phet Province, Thailand in 2017 and 2018. Mosquitoes were bisected into head-thorax and abdomen and then screened for Zika (ZIKV) and dengue (DENV) viruses using real-time RT-PCR. ZIKV RNA was detected in three samples from two female Ae. aegypti (1.4%). A partial envelope sequence analysis revealed that the ZIKV sequences were the Asian lineage identical to sequences from ZIKV-infected cases reported in Thailand during 2016 and 2017. Dengue virus-1 (DENV-1) and dengue virus-4 (DENV-4) were found in four Ae. aegypti females (2.8%), and partial capsid sequences were nearly identical with DENV-1 and DENV-4 from Thai human cases reported in 2017. Findings in the current study demonstrate the importance of entomological surveillance programs to public health mosquito-borne disease prevention measures and control.
Composition and Antioxidant Activities of Volatile Organic Compounds in Radiation-Bred Coreopsis Cultivars
Authors: Kim Bo-Ram , Kim Hyun Mi , Jin Chang Hyun , Kang Si-Yong , Kim Jin-Baek , Jeon Yeo Gyeong , Park Kong Young , Lee Ik-Soo , Han Ah-Reum
Published: June 2020

Coreopsis is a flowering plant belonging to the Asteraceae family. It is an ornamental plant native to the Americas, Asia and Oceania and its flower is used as a raw material for tea and food manufacture in China. In this study, new cultivars of C. rosea (“golden ring”) were developed via radiation-induced mutation of the original cultivar, “pumpkin pie”. The chemical composition and antioxidant activities of flowers belonging to three different Coreopsis cultivars were evaluated: “golden ring”, “pumpkin pie” and “snow chrysanthemum” (coreopsis tea; C. tinctoria). The volatile compounds were characterized via gas chromatography-mass spectrometry (GC-MS) and 50–59 oils representing 95.3–96.8% of the total volatile compounds in these flower materials were identified. ”Golden ring” contained a high amount of fatty acids (38.13%), while “pumpkin pie” and “snow chrysanthemum” teas were rich in aliphatic amides (43.01%) and esters (67.22%), respectively. The antioxidant activities of the volatile oils of these cultivars were evaluated using 1,1-diphenyl-2-picrylhydraxyl (DPPH) and 2,2-azino-bis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS) radical scavenging assays. The volatile extract of “golden ring” showed higher antioxidant activities compared with the extracts of the other cultivars. Therefore, “golden ring” can be used for further development as a raw material for tea manufacture or as a dietary supplement.
Experimental Evaluation of Low Velocity Impact Properties and Damage Progression on Bamboo/Glass Hybrid Composites Subjected to Different Impact Energy Levels
Authors: Md Shah Ain Umaira , Hameed Sultan Mohamed Thariq , Safri Syafiqah Nur Azrie
Published: June 2020

Six impact energy values, ranging from 2.5 J to 10 J, were applied to study the impact properties of neat epoxy and bamboo composites, while six impact energy values, ranging from 10 J to 35 J, were applied on bamboo/glass hybrid composites. Woven glass fibre was embedded at the outermost top and bottom layer of bamboo powder-filled epoxy composites, producing sandwich structured hybrid composites through lay-up and molding techniques. A drop weight impact test was performed to study the impact properties. A peak force analysis showed that neat epoxy has the stiffest projectile for targeting interaction, while inconsistent peak force data was collected for the non-hybrid composites. The non-hybrid composites could withstand up to 10 J, while the hybrid composites showed a total failure at 35 J. It can be concluded that increasing the filler loading lessened the severity of damages in non-hybrid composites, while introducing the woven glass fibre could slow down the penetration of the impactor, thus lowering the chances of a total failure of the composites.
Some Properties of Composite Drone Blades Made from Nanosilica Added Epoxidized Natural Rubber
Authors: Suchat Sunisa , Lanna Aunnuda , Chotikhun Aujchariya , Hiziroglu Salim
Published: June 2020

The objective of this study was to investigate the basic properties of composite materials that were made from epoxidized natural rubber and nanosilica to be used as blades for drones. Nanocomposite samples were prepared with 5% of epoxidized natural rubber and epoxy resin loaded with 3% nanosilica. Their resistance against accelerated weathering conditions as well as mechanical properties, including flexural strength, impact strength, and hardness, were evaluated. Based on the findings of this work, the impact strength of the samples decreased 13.33% and 33.33% as a result of exposing them to weathering by UV radiation for 168 h and 336 h, respectively. However, their tensile strength properties enhanced 35.71% and 19.05% for the above corresponding exposure time spars. Experimental composite samples that were made in this study would have great potential to be used as raw material for propeller blade for drones based on their properties evaluated within the scope of this work.
Kinetics, Isotherms, and Thermodynamic Modeling of the Adsorption of Phosphates from Model Wastewater Using Recycled Brick Waste
Authors: Edet Uduakobong A. , Ifelebuegu Augustine O.
Published: June 2020

Phosphates in wastewater at elevated concentrations cause eutrophication of water bodies and their removal from treated wastewater is essential before effluents are discharged to the environment. Phosphates are predominately removed during wastewater treatment by chemical precipitation which is usually expensive and has a significant environmental footprint. The purpose of this study was to investigate the effectiveness of waste recycled bricks as adsorbent for phosphate removal during wastewater treatment. The kinetics, isotherms, and thermodynamics of adsorption were investigated to establish the mechanisms of adsorption. The results showed that adsorption capacities increased with an increase in contact time, adsorbent dosage, and initial phosphate concentration. The kinetic study indicated that adsorption was governed by several mechanisms with various processes dominating different stages of the adsorption. The adsorption process was better represented by the pseudo-second-order kinetics and the Langmuir isotherm adequately described the adsorption of phosphates onto brick particles with a maximum adsorption capacity of 5.35 mg/g. The thermodynamic studies showed that the adsorption process was exothermic and proceeded spontaneously, demonstrating that waste bricks can be used as a sustainable alternative for the effective removal of phosphates from wastewater.
Deposition of Boron-Doped Thin CVD Diamond Films from Methane-Triethyl Borate-Hydrogen Gas Mixture
Authors: Polushin Nikolay Ivanovich , Laptev Alexander Ivanovich , Spitsyn Boris Vladimirovich , Alexenko Alexander Evgenievich , Polyansky Alexander Mihailovich , Maslov Anatoly Lvovich , Martynova Tatiana Vladimirovna
Published: June 2020

Boron-doped diamond is a promising semiconductor material that can be used as a sensor and in power electronics. Currently, researchers have obtained thin boron-doped diamond layers due to low film growth rates (2–10 μm/h), with polycrystalline diamond growth on the front and edge planes of thicker crystals, inhomogeneous properties in the growing crystal’s volume, and the presence of different structural defects. One way to reduce structural imperfection is the specification of optimal synthesis conditions, as well as surface etching, to remove diamond polycrystals. Etching can be carried out using various gas compositions, but this operation is conducted with the interruption of the diamond deposition process; therefore, inhomogeneity in the diamond structure appears. The solution to this problem is etching in the process of diamond deposition. To realize this in the present work, we used triethyl borate as a boron-containing substance in the process of boron-doped diamond chemical vapor deposition. Due to the oxygen atoms in the triethyl borate molecule, it became possible to carry out an experiment on simultaneous boron-doped diamond deposition and growing surface etching without the requirement of process interruption for other operations. As a result of the experiments, we obtain highly boron-doped monocrystalline diamond layers with a thickness of about 8 μm and a boron content of 2.9%. Defects in the form of diamond polycrystals were not detected on the surface and around the periphery of the plate.
Catalytic and Non-Catalytic Treatment of Industrial Wastewater under the Exposure of Non-Thermal Plasma Jet
Authors: Shukrullah Shazia , Bashir Warda , Altaf Noor Ul Huda , Khan Yasin , Al-Arainy Abdulrehman Ali , Sheikh Toqeer Ahmad
Published: June 2020

Freshwater is only 2.5% of the total water on the Earth and rest is contaminated or brackish. Various physical and chemical techniques are being used to purify the contaminated water. This study deals with catalytic plasma treatment of contaminated water collected from different sites of Faisalabad-Pakistan. A non-thermal DC plasma jet technique was used to treat the water samples in the presence of TiO2 catalyst. The plasma-assisted catalytic treatment introduced some oxidative species (O3, H2O2, HO2−, OH−) in the water. These species reacted with pollutants and cause the degradation of harmful contaminants, especially dyes. The degradation of dye sample during plasma treatment was more pronounced as compared to other samples. pH, conductivity and TDS of dye containing sample decreased after catalytic plasma treatment. The degradation of organic pollutants increased due to presence of several oxidants, such as TiO2, ferrous ions and hydrogen peroxide. FT-IR analysis revealed the degradation of some functional groups during treatment process and confirmed the effectiveness of the process. The residue of the treated samples was consisted of amines, amides and N-H functional groups. XRD analysis showed the presence of Alite, Ferrite, aluminate, Si, S and some heavy metals in the residue. The effect of plasma treatment on activity of gram-negative Escherichia coli (E. coli) bacteria in water was also checked. The bacterial activity was reduced by almost 50% after 2 min of plasma treatment.
Sustainable Environmental Management and Valorization Options for Olive Mill Byproducts in the Middle East and North Africa (MENA) Region
Authors: Khdair Adnan , Abu-Rumman Ghaida
Published: June 2020

Cultivation of olive trees and olive oil production have been considered as a legacy for the Mediterranean region. This custom represents a very important benefit for many nations in terms of wealth and health. However, huge amounts of by-products and waste are generated during olive oil production. This represents a serious environmental impact on land and water bodies if not properly handled. Olive oil extraction generates two waste streams, a solid waste called pomace and olive mill wastewater (OMWW), which has been considered as highly pollutant and phytotoxic waste. These wastes have high disposal costs and predominantly generated from small-scale enterprises that have limited financial resources to treat them properly before discharge to the environment. Besides being a serious environmental problem, OMWW has potential economic value that remains to be utilized such as: fertilizers, valuable antioxidants agents and fatty acids needed in human diet. Also, Olive pomace is a valuable renewable energy source with an energy density of 23 MJ/kg and has become an inexpensive alternative for fossil fuels. Aiming at adding value to the olive production sectors and potential valorization options for byproducts in the MENA region, international practices applied in olive mills wastes management’s and treatment methods used in major oil producing countries are presented.
Stewarding National User Groups to Strengthen Open Source Software Communities
Authors: Becker Pascal-Nicolas , Mennielli Michele , Trachte Katharina
Published: June 2020

Open Source Software (OSS) communities are often international, bringing together people from diverse regions with different linguistic and cultural backgrounds. National user groups can bolster these international communities by convening local events, championing the software to peers, welcoming and onboarding new contributors, raising money to support the broader community, and collecting important information on user’s needs. The open source community-led software DSpace has had great success encouraging the creation of national user groups; in the UK, North America, and Germany, the Groups have been active for many years. However, it was in 2018, thanks to a renewed focus on international engagement and more diverse representation of the global community in governance groups, that the national communities entered into a new phase: 15 new national User Groups have been formed all over the world since then, while the German user group evolved into the “DSpace-Konsortium Deutschland”, founded by 25 institutions, marking a pivotal point for membership options and National User Group participation within DSpace Governance. This article will offer an overview of the historical development of the DSpace community and its governance model, as well as DuraSpace’s international engagement strategy, including its benefits and challenges. Subsequently, we will present a case study on the DSpace-Konsortium Deutschland and explain its relation to the broader context of how to build national user groups within global communities.
GEOTOURISM as a Tool for Learning: A Geoitinerary in the Cilento, Vallo di Diano and Alburni Geopark (Southern Italy)
Authors: Santangelo Nicoletta , Amato Vincenzo , Ascione Alessandra , Russo Ermolli Elda , Valente Ettore
Published: June 2020

“Geotourism” is a particular type of “sustainable tourism” that is still in an embryonic stage, especially in Italy. The main goal is the transmission of geological knowledge to increase the awareness about geoheritage, geo-resources and geo-hazards. The geoparks represent ideal sites, with a strong educational significance for students, teachers, geo-tourists, and guides interested in geological and environmental sciences, though at different levels. With this in mind, we propose a geoitinerary through some of the most geologically interesting coastal areas in the Cilento, Vallo di Diano, and Alburni Geopark. The aim of the geoitinerary is to provide a good example of how geosites could be promoted through geotourism and used as means of divulgation of geological and environmental knowledge. The selected sites are the San Marco coast, the Licosa Cape and the Elea-Velia archaeological area. They are included in the official list of geosites and geomorphosites of the Geopark and have a relevant stratigraphic and geoarcheological value. The San Marco coast and the Licosa Cape are the “best sites” in the Geopark where Quaternary coastal deposits and morphologies are represented. The Elea-Velia site is one of the most famous archeological sites in the Geopark, which is also representative of complex human-environment interactions. Despite their high scientific significance, the sites that we have selected are not included in a specific promoting program. We have so tried to fill this gap by providing the scientific background for their geotouristic promotion that could also serve as an instrument for the increase of the local economy.
Evaluation of Precipitable Water Vapor from Five Reanalysis Products with Ground-Based GNSS Observations
Authors: Wang Shuaimin , Xu Tianhe , Nie Wenfeng , Jiang Chunhua , Yang Yuguo , Fang Zhenlong , Li Mowen , Zhang Zhen
Published: June 2020

At present, the global reliability and accuracy of Precipitable Water Vapor (PWV) from different reanalysis products have not been comprehensively evaluated. In this study, PWV values derived by 268 Global Navigation Satellite Systems (GNSS) stations around the world covering the period from 2016 to 2018 are used to evaluate the accuracies of PWV values from five reanalysis products. The temporal and spatial evolution is not taken into account in this analysis, although the temporal and spatial evolution of atmospheric flows is one of the most important information elements available in numerical weather prediction products. The evaluation results present that five reanalysis products with PWV accuracy from high to low are in the order of the fifth generation of European Centre for Medium-Range Weather Forecasts (ECMWF) Reanalysis (ERA5), ERA-Interim, Japanese 55-year Reanalysis (JRA-55), National Centers for Environmental Prediction/National Center for Atmospheric Research (NCEP/NCAR), and NCEP/DOE (Department of Energy) according to root mean square error (RMSE), bias and correlation coefficient. The ERA5 has the smallest RMSE value of 1.84 mm, while NCEP/NCAR and NCEP/DOE have bigger RMSE values of 3.34 mm and 3.51 mm, respectively. The findings demonstrate that ERA5 and two NCEP reanalysis products have the best and worst performance, respectively, among five reanalysis products. The differences in the accuracy of the five reanalysis products are mainly attributed to the differences in the spatial resolution of reanalysis products. There are some large absolute biases greater than 4 mm between GNSS PWV values and the PWV values of five reanalysis products in the southwest of South America and western China due to the limit of terrains and fewer observations. The accuracies of five reanalysis products are compared in different climatic zones. The results indicate that the absolute accuracies of five reanalysis products are highest in the polar regions and lowest in the tropics. Furthermore, the effects of different seasons on the accuracies of five reanalysis products are also analyzed, which indicates that RMSE values of five reanalysis products in summer and in winter are the largest and the smallest in the temperate regions. Evaluation results from five reanalysis products can help us to learn more about the advantages and disadvantages of the five released water vapor products and promote their applications.
Modelling Crop Biomass from Synthetic Remote Sensing Time Series: Example for the DEMMIN Test Site, Germany
Authors: Dhillon Maninder Singh , Dahms Thorsten , Kuebert-Flock Carina , Borg Erik , Conrad Christopher , Ullmann Tobias
Published: June 2020

This study compares the performance of the five widely used crop growth models (CGMs): World Food Studies (WOFOST), Coalition for Environmentally Responsible Economies (CERES)-Wheat, AquaCrop, cropping systems simulation model (CropSyst), and the semi-empiric light use efficiency approach (LUE) for the prediction of winter wheat biomass on the Durable Environmental Multidisciplinary Monitoring Information Network (DEMMIN) test site, Germany. The study focuses on the use of remote sensing (RS) data, acquired in 2015, in CGMs, as they offer spatial information on the actual conditions of the vegetation. Along with this, the study investigates the data fusion of Landsat (30 m) and Moderate Resolution Imaging Spectroradiometer (MODIS) (500 m) data using the spatial and temporal reflectance adaptive reflectance fusion model (STARFM) fusion algorithm. These synthetic RS data offer a 30-m spatial and one-day temporal resolution. The dataset therefore provides the necessary information to run CGMs and it is possible to examine the fine-scale spatial and temporal changes in crop phenology for specific fields, or sub sections of them, and to monitor crop growth daily, considering the impact of daily climate variability. The analysis includes a detailed comparison of the simulated and measured crop biomass. The modelled crop biomass using synthetic RS data is compared to the model outputs using the original MODIS time series as well. On comparison with the MODIS product, the study finds the performance of CGMs more reliable, precise, and significant with synthetic time series. Using synthetic RS data, the models AquaCrop and LUE, in contrast to other models, simulate the winter wheat biomass best, with an output of high R2 (>0.82), low RMSE (<600 g/m2) and significant p-value (<0.05) during the study period. However, inputting MODIS data makes the models underperform, with low R2 (<0.68) and high RMSE (>600 g/m2). The study shows that the models requiring fewer input parameters (AquaCrop and LUE) to simulate crop biomass are highly applicable and precise. At the same time, they are easier to implement than models, which need more input parameters (WOFOST and CERES-Wheat).