bluuebunny/crossref_metadata_2025 huggingface dataset:
Emissions Control Scenarios for Transport in Greater Cairo
Authors: Alaa Abbass Rana , Kumar Prashant , El-Gendy Ahmed
Published: November 2021

Air pollution is a major cause of premature death in Greater Cairo, but studies on emission control are limited. We used local and international data to predict the impact of transport emission control measures on sector parameters including congestion. The International Vehicle Emission model accordingly estimated quantities of criteria, toxic and global warming emissions produced by on-road vehicles. Emissions were estimated for 2019 base case (2019-BC) and projected for 2030 under the ‘do nothing’ scenario (2030-DNS) and five scenarios: fuel subsidy removal (2030-FSR), road expansions (2030-RE), public transport improvements (2030-PTI), inspection and maintenance (I/M) programs (2030-I/MP), and fuel enhancements (2030-FE). The 2030-FSR would reduce emissions by 11.2% versus 2030-DNS. The 2030-RE resulted in an average increase of 37% in emissions compared with 2030-DNS since it induces more traffic. The 2030-PTI provides alternatives to car travel; hence, cars result in an average drop of 32.8% for all emission types compared with 2030-DNS. The 2030-I/MP exhibited reductions in PM10 and toxic pollutants, of 35–54.8% compared with 2030-DNS. The 2030-FE reduced SOx, benzene and N2O emissions by 91.8%, 81% and 39.1%, respectively, compared with 2030-DNS. The 2030-I/MP is most effective in reducing health damaging pollutants while 2030-PTI positively impacts commuters’ lifestyle.
Methylmercury-Induced Metabolic Alterations in Caenorhabditis elegans Are Diet-Dependent
Authors: Crawford Nicole , Martell Megan , Nielsen Tyson , Khalil Belal , Imtiaz Farooq , Nguidjo Etienne , Newell-Caito Jennifer , Bornhorst Julia , Schwerdtle Tanja , Caito Samuel
Published: November 2021

Methylmercury (MeHg) is a well-known neurotoxicant; however, its role in metabolic diseases has been gaining wider attention. Chronic exposure to MeHg in human populations shows an association with diabetes mellitus and metabolic syndrome (MS). As the incidences of both obesity and MS are on the rise globally, it is important to understand the potential role of MeHg in the development of the disease. There is a dearth of information on dietary interactions between MeHg and lipids, which play an important role in developing MS. We have previously shown that MeHg increases food seeking behaviors, lipid levels, fat storage, and pro-adipogenic gene expression in C. elegans fed the standard OP50 Escherichia coli diet. However, we hypothesized that these metabolic changes could be prevented if the worms were fed a bacterial diet lower in lipid content. We tested whether C. elegans developed metabolic alterations in response to MeHg if they were fed two alternative E. coli strains (HT115 and HB101) that are known absorb significantly less lipids from their media. Additionally, to explore the effect of a high-lipid and high-cholesterol diet on MeHg-induced metabolic dysfunction, we supplemented the OP50 strain with twice the standard concentration of cholesterol in the nematode growth media. Wild-type worms fed either the HB101 or HT115 diet were more resistant to MeHg than the worms fed the OP50 diet, showing a significant right-hand shift in the dose–response survival curve. Worms fed the OP50 diet supplemented with cholesterol were more sensitive to MeHg, showing a significant left-hand shift in the dose–response survival curve. Changes in sensitivity to MeHg by differential diet were not due to altered MeHg intake in the worms as measured by inductively coupled mass spectrometry. Worms fed the low-fat diets showed protection from MeHg-induced metabolic changes, including decreased food consumption, lower triglyceride content, and lower fat storage than the worms fed either of the higher-fat diets. Oxidative stress is a common characteristic of both MeHg exposure and high-fat diets. Worms fed either OP50 or OP50 supplemented with cholesterol and treated with MeHg had significantly higher levels of reactive oxygen species, carbonylated proteins, and loss of glutathione than the worms fed the HT115 or HB101 low-lipid diets. Taken together, our data suggest a synergistic effect of MeHg and dietary lipid levels on MeHg toxicity and fat metabolism in C. elegans, which may affect the ability of MeHg to cause metabolic dysfunction.
Methicillin-Resistant Coagulase Negative Staphylococci and Their Antibiotic Susceptibility Pattern from Healthy Dogs and Their Owners from Kathmandu Valley
Authors: Khanal Muna , Joshi Prabhu Raj , Paudel Saroj , Acharya Mahesh , Rijal Komal Raj , Ghimire Prakash , Banjara Megha Raj
Published: November 2021

This cross-sectional study was designed to identify information on the frequency, antimicrobial resistance and species diversity of methicillin-resistant coagulase negative staphylococci (MRCoNS) among pet dogs and humans within households. Fifty five nasal swabs each from dogs and their owners were collected. MRCoNS were identified based on gram staining, culture on mannitol salt agar, biochemical tests, and mecA gene amplification. The antibiotic susceptibility of the isolates was assessed by a disc diffusion test. Uniplex and multiplex polymerase chain reaction (PCR) were employed for the species identification of MRCoNS and SCCmec typing, respectively. Species were further confirmed by MALDI-TOF-MS. The prevalence of MRCoNS was 29% in dog owners and 23.6% in dogs. Four different species of MRCoNS, Staphylococci saprophyticus (48.3%), S. haemolyticus (24.1%), S. warneri (17.2%), and S. epidermidis (10.3%), were detected. Two isolates each from dog owners and dogs showed a constitutive resistance to macrolide-lincosamide-streptogramin B (cMLSB) resistance, eight isolates each from dogs and their owners showed a macrolide-streptogramin B (MSB) resistance, and only two isolates from dog owners revealed an inducible resistance to macrolide-lincosamide-streptogramin B (iMLSB) resistance. SCCmec types were SCCmec type IV (55.2%), SCCmec type V (24.1%), SCCmec III (10.3%), SCCmec II (3.4%); two isolates were non-typable. MRCoNS are prevalent and genetically diverse in companion animals and humans. Different species of MRCoNS were found in dogs and their owners.
Review on Indirect Dark Matter Searches with Neutrino Telescopes
Authors: Zornoza Juan de Dios
Published: November 2021

The search for dark matter is one of the hottest topics in Physics today. The fact that about 80% of the matter of the Universe is of unknown nature has triggered an intense experimental activity to detect this kind of matter and a no less intense effort on the theory side to explain it. Given the fact that we do not know the properties of dark matter well, searches from different fronts are mandatory. Neutrino telescopes are part of this experimental quest and offer specific advantages. Among the targets to look for dark matter, the Sun and the Galactic Center are the most promising ones. Considering models of dark matter densities in the Sun, neutrino telescopes have put the best limits on spin-dependent cross section of proton-WIMP scattering. Moreover, they are competitive in the constraints on the thermally averaged annihilation cross-section for high WIMP masses when looking at the Galactic Centre. Other results are also reviewed.
Gravitational Effects on Neutrino Decoherence in the Lense–Thirring Metric
Authors: Luciano Giuseppe Gaetano , Blasone Massimo
Published: November 2021

We analyze the effects of gravity on neutrino wave packet decoherence. As a specific example, we consider the gravitational field of a spinning spherical body described by the Lense–Thirring metric. By working in the weak-field limit and employing Gaussian wave packets, we show that the characteristic coherence length of neutrino oscillation processes is nontrivially affected, with the corrections being dependent on the mass and angular velocity of the gravity source. Possible experimental implications are finally discussed.
Ringing of the Regular Black Hole with Asymptotically Minkowski Core
Authors: Simpson Alexander Marcus
Published: November 2021

A Regge–Wheeler analysis is performed for a novel black hole mimicker ‘the regular black hole with asymptotically Minkowski core’, followed by an approximation of the permitted quasi-normal modes for propagating waveforms. A first-order WKB approximation is computed for spin zero and spin one perturbations of the candidate spacetime. Subsequently, numerical results analysing the respective fundamental modes are compiled for various values of the a parameter (which quantifies the distortion from Schwarzschild spacetime), and for various multipole numbers ℓ. Both electromagnetic spin one fluctuations and scalar spin zero fluctuations on the background spacetime are found to possess shorter-lived, higher-energy signals than their Schwarzschild counterparts for a specific range of interesting values of the a parameter. Comparison between these results and some analogous results for both the Bardeen and Hayward regular black holes is considered. Analysis as to what happens when one permits perturbations of the Regge–Wheeler potential itself is then conducted, first in full generality, before specialising to Schwarzschild spacetime. A general result is presented explicating the shift in quasi-normal modes under perturbation of the Regge–Wheeler potential.
Development of a Double-Antibody Sandwich ELISA for Rapid Detection of the MCP Antigen Concentration in Inactivated ISKNV Vaccines
Authors: Liang Hongru , Zhang Lixi , Fu Xiaozhe , Lin Qiang , Liu Lihui , Niu Yinjie , Luo Xia , Huang Zhibin , Li Ningqiu
Published: November 2021

Infectious spleen and kidney necrosis virus (ISKNV) resulted in severe systemic diseases with high morbidity and mortality in Siniperca chuatsi. Vaccination is the primary method for effective prevention and control of these diseases. The development of inactivated ISKNV vaccines made some progress, but the technique of quality evaluation is scarce. Herein, a measurement of the MCP (major capsid protein) antigen concentration for the inactivated ISKNV vaccine was developed by double-antibody sandwich ELISA. Firstly, mouse monoclonal antibodies against ISKNV particles and MCP were generated. Then, a double-antibody sandwich ELISA was developed using the monoclonal antibody 1C8 1B9 as the capture antibody and Biotin-3B12 6B3 as the detection antibody. A standard curve was generated using the MCP concentration versus OD value with the linear range of concentration of 4.69~300 ng/mL. The assay sensitivity was 0.9 ng/mL. The antigen content of three batches of inactivated ISKNV vaccines was quantitatively detected using the double-antibody sandwich ELISA. The results showed that MCP antigen contents of inactivated ISKNV vaccines were positively correlated with the viral titers. The newly established double-antibody sandwich ELISA provided a useful tool for the detection of antigen quality for ISKNV inactivated vaccines.
Bilateral Renal Large B Cell Lymphoma in a Dog: A Case Report and Review of the Literature
Authors: Apostolopoulou Emmanouela P. , Vlemmas Ioannis , Pardali Dimitra , Adamama-Moraitou Katerina K. , Poutahidis Theofilos , Papadopoulou Paraskevi L. , Brellou Georgia D.
Published: November 2021

Canine lymphoma is a commonly reported neoplasia and, in most dogs, arises from lymph nodes before spreading to other organs. Renal lymphoma rarely occurs, and kidneys usually are a secondary site of origin. Primary renal lymphoma is infrequently described in the veterinary literature. In this study, we present a rare case of primary renal lymphoma in a dog and a review of similar cases. A 3-year-old male dog was admitted due to anorexia, weakness and vomiting. Clinical examination revealed bilaterally enlarged kidneys. Imaging demonstrated the presence of multiple renal masses. Cytology of abdominal fluid and kidneys led to the diagnosis of large cell lymphoma. Histopathology and immunohistochemistry on tissue samples taken from the kidneys confirmed the cytological diagnosis of lymphoma and categorized it as primary bilateral renal large B-cell lymphoma (LBCL).
D. ZILBERMAN’S MODAL METHODOLOGY AND THE PHENOMENON OF THE PLAY: FEATURES OF CONCEPTUALIZATION
Authors: Lysokolenko Tetiana
Published: October 2021

There is an opinion about the prospects of studying the play in the context of language, culture and media. The phenomenon of the play through the prism of deontic, apodictic and hypothetical levels of D. Zilberman’s modal methodology is presented. It is revealed that at the deontic level of modalization, the play, as part of the indicated planes, is revealed through the concept of language games by L. Wittgenstein, understanding the essence of the play in the culture of J. Huizinga, F. Schiller and G. Hesse and in the context of “mass media reality” by N. Luhmann. It is substantiated that the dynamism of language development, the application of the game approach to the characterization of culture and the representation of the media space as a total play (J. Baudrillard) represent the essence of the apodictic level of modalization of the phenomenon of the play. It is proposed to comprehend the hypothetical level of modalization of the play by demonstrating the process of transformation of the research phenomenon in the context of language, culture and media, manifested through the theory of performatives, the phenomenon of Bakhtin’s carnival and manipulations, information throws and fakes in media reality.
PHILOSOPHICAL AND THEOLOGICAL CONCEPT OF JOHN HARVEY KELLOGG IN RELATION TO THE PRINCIPLES OF A HEALTHY LIFESTYLE
Authors: Kuryliak Valentyna
Published: October 2021

Examining the ideas of the Living Temple, it was found that it contains a description of the principles of health according to which it is necessary to take care of the human body. According to Kellogg, the stated principles of health care are in harmony with the laws of nature and the Bible. The title of the book reflects the core and essence of Kellogg's philosophy, which calls the human body a "living temple." Kellogg based this concept on the words of the Apostle Paul: "Your body is the temple of the Holy Spirit" (1 Corinthians 6:19). Kellogg was convinced that a man living in a civilized environment had departed far from the divine ideal that was originally proposed for the comfortable life of man.
Organizational and legal framework for the functioning of the National Police investigation units
Authors: Romanov Maksym , Vasylynchuk Viktor , Grytsyshen Dymytrii , Melnyk Oksana , Denysiuk Denys
Published: October 2021

The purpose of the article is a scientific interpretation of the concept, essence and general structure of the organizational and legal framework for the functioning of inquiry units of the National Police of Ukraine and their regulatory support. The subject of the study is the organizational and legal basis for the functioning of inquiry units of the National Police of Ukraine. The research methodology includes the use of general scientific and special methods of scientific cognition: dialectical, logical, normative and dogmatic, logical and semantic, monographic, method of generalization. Research results. The analysis of approaches to understanding the concept and essence of organizational and legal framework for inquiry units of the National Police of Ukraine is carried out. The notion and significance of normative bases, which are focused on providing organizational and legal support for law enforcement agencies in general and inquiry units of the National Police of Ukraine, in particular, are outlined. Practical implication. The significance and elements of organizational and legal framework in the context of sustainable and stable functioning of inquiry units of the National Police of Ukraine are clarified. Value / originality. The problems are outlined and recommendations for their possible solution and improvement of the relevant institution are developed.
Modeling sensitivity indices of industrial enterprise organizational change
Authors: Bilyk Victoriia , Kolomytseva Olena , Myshkovych Olha , Tymoshyk Nataliia , Shcherbatykh Denis
Published: October 2021

Evaluation of sensitivity of commercial enterprises to organizational changes should be made in terms of short-term planning for which it is important to ensure the financial results, as well as in terms of long-term planning, which is important for non-monetary indicators of development effectiveness. To solve this problem, the paper is designed model sensitivity Descriptive indicators of industrial enterprises to organizational changes, reflecting monetary and non-monetary effects of organizational change. The authors determined that the proposed model allows for the analysis of organizational change with regard to their impact on monetary and non-monetary efficiency.

This paper contributes to the theory and practice at the border to ensure a balance between short-term and long-term development of industrial enterprises. Convincingly demonstrated the possibility of using research results in practice.
Science organization of management as a method of production systems’ effectiveness increasing
Authors: Zakharova Lilya F.
Published: October 2021

Modern high-tech production must be highly-effective and competitive, what is possible only when effective management system is available. There are disadvantages and problems of domestic machine-building enterprises and their practical experience. On the basis of made research with using fundamental theoretical and applied developments in the sphere of increasing management there is suggested conceptual appearance of a unique prognostic system of machine-building enterprises not mass production, the choice of directions of increasing these enterprises’ operative management system is justified. The purpose of the article is to propose ways to improve the efficiency of manufacturing enterprises. The methodology used in conducting this study and developing proposals for increasing the efficiency of production systems is based on the principles and methods of the general theory of management, its cybernetic and social components, as well as methods of specific management sciences for the creation and effective functioning of enterprise management mechanisms.
Particularidades de las réplicas en el proceso de la comunicación lingüística intercultural en la etapa inicial de la conversación telefónica, entre representantes de los países hispano y ruso-hablantes
Authors: Goicochea Morales Lorenzo Benjamín , Kapustina Daria M.
Published: October 2021

En el presente trabajo se lleva a cabo un análisis de la literatura sobre el problema de la comunicación intercultural, incluyendo la conversación telefónica, entre representantes de los países hispano y ruso-hablantes. Cobra especial relevancia el análisis de las peculiaridades de las réplicas en el proceso de la comunicación lingüística intercultural en la etapa inicial de una conversación telefónica, entre representantes de países hispanohablantes y de habla rusa, ya que contribuye a la interacción de las culturas y al enriquecimiento del acervo lingüístico de sus participantes. El objetivo del presente trabajo fue analizar las réplicas clave durante las conversaciones telefónicas entre representantes de varios países de habla hispana. El autor utiliza réplicas de clichés en diferentes etapas de una conversación telefónica y describe las razones para elegir una u otra réplica. Además, el autor presta especial atención a las réplicas usadas en el inicio de la conversación telefónica. El principal método de investigación para obtener información sobre el tema del trabajo fue la entrevista realizada con interlocutores hispanos sobre temas específicos. Además, se realizó un análisis de contenido de las conversaciones telefónicas para identificar las réplicas más repetitivas.
Relationship between quality of work-life and individual work performance: Moderating role of organizational culture
Authors: Kundi Ghulam Muhammad
Published: October 2021

The study aimed to find the contingent role of organizational culture upon relation and cooperation, and facilities provided to employees at the workplace to enhance individual’s work performance. A cross-survey approach was adopted. A total of 400 complete questionnaires were used in the analysis. SPSS-25 was used for the analysis of data. Hierarchical multiple regression was employed to test the hypotheses. It was found that there is a significant moderating role of organizational culture upon relation and cooperation, and facilities provided to employees to enhance individual work performance. The study finds that there is an intense need to improve the quality of work-life and workplace of health professionals so they deliver their best to achieve organizational objectives. The study recommends that there is a need to a supportive culture because it plays an instrumental role in bringing the desired level of performance which ultimately leads the organization to success. This study was conducted in healthcare organizations; the findings of this study could only be generalized into the health sector.
Effect of Zinc Oxide Nanoparticles on Loaded Antibiotics Against Multidrug-Resistant Acinetobacter spp.
Authors: Shokrollahi Behnaz , Tabatabaee Bafroee Akram Sadat , Saleh Tayebeh
Published: November 2021

Background: Metal oxide nanoparticles (NPs) have shown promising efficacy for combating bacterial resistance due to their antibacterial properties. This research investigated the effect of zinc oxide NPs (ZnO-NPs) on the antibacterial activity of conventional antibiotics including ciprofloxacin (CIP), cefotaxime (CTX), and colistin (CST) against multidrug-resistant Acinetobacter isolates. Methods: The disc diffusion method was performed to detect the pattern of antibiotic resistance in isolates. The synthesized ZnO-NPs via the solvothermal method were characterized by field emission scanning electron microscopy (FESEM), X-ray diffraction (XRD), and energy-dispersive X-ray spectroscopy (EDS). Finally, the broth microdilution technique was conducted to demonstrate the antibacterial activity of CIP, CTX, and CST antibiotics with and without a sub-inhibitory concentration of ZnO-NPs. Results: XRD, EDS, and FESEM results confirmed the crystalline structure of ZnO-NPs, and the average size was 100±58.68 nm. All isolates were discovered to be of multidrug-resistant (MDR) type and fully susceptible to CST. The antibacterial activity of CTX and CIP was restored when combined with a sub-inhibitory level of ZnO-NPs (0.25 mg/L), and the highest activity was obtained at the concentrations of 32 µg/mL CTX and 8 µg/ mL CIP. Eventually, ZnO-NPs showed a synergistic effect on the antibacterial properties of CST against MDR Acinetobacter. Conclusions: This research indicated that the combination of ZnO-NPs with some common antibiotics can be considered as a novel strategy for reducing the spread of antibiotic-resistant bacteria.
Spectroscopic Characteristics of Xeloda Chemodrug
Authors: Abdollahi Jahdi Sahar , Parvin Parviz , Seyedi Solaleh , Jelvani Saeid , Razzaghi Mohammad Reza
Published: November 2021

Introduction: Spectroscopic properties of Xeloda chemodrug have been studied over varying concentrations ranging between 0.001 and 10 mg/mL, using laser-induced fluorescence (LIF) spectroscopy. The alternative photoluminescence (PL) and near infrared (NIR) measurements are carried out to authenticate the obtained results by the LIF method. Methods: The XeCl laser as the excitation coherent source with 160 mJ/pulse at 308 nm is employed for LIF measurements of the fluorophore of interest in the modular spectroscopic set-up. Results: Xeloda as a significant chemodrug acts as a notable fluorophore. LIF, PL and NIR spectroscopy techniques are employed to investigate the spectral properties of the chemodrug in terms of concentration. The maximum LIF peak intensity of Xeloda is achieved at λmax=410.5 nm and the characteristic concentration of CP1=0.05 mg/mL. PL signals are in good agreement with the data given by the LIF measurements. The characteristic NIR spectra of Xeloda as solid evidence of chemical bonding formation attest to fluorescence quenching at the fluorophore concentration of ~ 0.2 mg/ mL. Besides, the spectral shift of fluorescence signals which is obtained in terms of fluorophore concentration- demonstrating as a diagnostic marker for the purpose of optimized chemotherapy. Conclusion: Xeloda exhibits outstanding fluorescence properties over the allowable concentration in human serum (Cmax). These characteristics could benefit potential advantage of simultaneous laser-based imaging of cell-chemodrug interaction over in-vivo studies.
Review of Laser Therapy in Cardiovascular Diseases
Authors: Karvandi Mersedeh
Published: November 2021

Introduction: In recent years, there has been a rise in laser therapy for the treatment of cardiovascular diseases. Methods: This paper attempted to represent recent advances in laser therapy in cardiovascular tissue repairs. Three standard techniques have been explicitly described here in cardiovascular tissue repairs by laser. Results: One of the advantages of using laser therapy in cardiovascular diseases is its non-invasiveness. It also reduces the treatment process pain and prevents massive surgical incisions and bleeding throughout the operation. Laser therapy can ensure an alternative method to treat the ischemic region of the heart and creating anastomosis of vessels. Conclusion: With professional technologies and endoscopic surgery method development, the role of using lasers has become much more precise and more transparent in cardiovascular diseases.
Intravaginal Pulsed Contractile Radiofrequency for Stress Urinary Incontinence Treatment; A Safety Study
Authors: Razzaghi Mohammadreza , Asghari-azghan Afsar , Montazeri Saeed , Razzaghi Zahra , Mazloomfard Mohammad Mohsen , Vafaee Reza
Published: November 2021

Introduction: Radiofrequency (RF)-based stress urinary incontinence (SUI) treatment, which has quickly attracted attention, is administered in an office setting. This pilot-safety study assessed the efficacy of transvaginal RF treatment in the quality of life (QOL) and frequency of incontinence episodes in women with SUI. Methods: Twenty-eight women suffering from SUI were treated with an intravaginal quadric applicator while a grounding pad was attached in front of their pubes. The first phase is thermic, which will heat up the vaginal wall up to 40°C for 10 minutes. The second step is contraction to stimulate an aerobic exercise of pelvic floor muscles for 20 minutes (pulsed contractile RF at 20-40 watts and 1000-300 kHz with a modulation of 1 to 300 Hz for muscle exercise). It was scheduled for one session per week for 3 sessions. Patients had follow-up visits before and 1, 6 and 12 months following the treatment for one-day voiding diary, Persian version of urinary incontinence QOL questionnaire (I-QOL), Q-tip test, 24 hours-pad test and daily incontinence episodes’ number. Results: The patients’ mean age, duration of incontinence and median vesical leak point pressure were 41.6±9.6 years, 5.48±6.84 years and 140 cm H2 O respectively. Significant changes were observed in the mean I-QOL total score and the pad test. Also, a notable reduction was observed in the number of daily leakage episodes and the Q-tip test at any follow-up visit (P=0.001). Conclusion: Preliminary results suggest that transvaginal RF is a convenient method of SUI treatment. Significant changes were observed in the mean I-QOL total score and the pad test. Also, a notable reduction was observed in the number of daily leakage episodes.
Comparative Study Between the efficacy of Long-Pulsed Neodymium- YAG Laser and Fractional Co2 Laser in the Treatment of Striae Distensae
Authors: Hendawy Alyaa Farouk , Aly Dalia Gamal , Shokeir Hisham Aly , Samy Nevien Ahmed
Published: November 2021

Introduction: Stretch marks, or striae distensae (SD), are the lesions of the dermis caused by its linear atrophy at the sites of stretching. They occur in more than 70% of pregnant women and adolescents as a result of cutaneous stretching. This study aimed at evaluating and comparing the clinical and histological efficacy of the fractional CO2 laser versus the long pulsed (LP) Nd: YAG laser in the treatment of striae alba. Methods: Thirty female subjects having bilateral symmetrical stretch marks were managed by the LP Nd: YAG laser on the right side and the fractional CO2 laser on the left side. The laser treatment course consisted of 3 sessions with an interval of 3 weeks. The patient satisfaction score and the Global Aesthetic Improvement Scale (GAIS) were employed in the study in order to assess the improvement 3 months after therapy. Punch biopsies measuring 4 mm were extracted from one lesion on each side at baseline and after the last treatment session by 3 months to evaluate the thickness of both collagen and epidermis Results: Clinical improvement was more significant in the lesions treated by the LP Nd:YAG laser than those treated with the fractional CO2 laser. The patient satisfaction score and the GAIS were higher with a statistically significant value in the side treated by the LP Nd:YAG laser. Collagen and epidermal thickness increased more in the LP Nd: YAG laser-treated lesions in comparison to their thickness in the fractional CO2 laser-managed lesions, but this difference did not have a statistical significance. Conclusion: The clinical efficacy of the LP Nd-YAG laser exceeded that of the fractional CO2 laser in the treatment of striae alba without severe side effects in spite of the insignificant histological difference between the two lasers.
The Principal Role of Several Members of HLA and IRF Genes in Prevention of Oral Mucositis After Chemoradiotherapy
Authors: Arjmand Babak , Khodadost Mahmood , Jahani Sherafat Somayeh , Rezaei Tavirani Mostafa , Ahmadi Nayebali , Hamzeloo Moghadam Maryam , Okhovatian Farshad , Rezaei Tavirani Sina
Published: November 2021

Introduction: One of the chemoradiotherapy (CRT) side effects is oral mucositis (OM). Since photobiomodulation therapy (PBMT) is a public method for the repair process, in the present study the mechanism of PBMT in the prevention of OM is investigated via the bioinformatics approach. Methods: Six validated and significant differentially expressed genes (DEGs) associated with the prevention of OM in head and neck cancer (HNC) patients who had experienced CRT were extracted from the literature. After adding 50 neighbors from STRING, the network was constructed and analyzed. The results of the action map and network analysis were compared and discussed. Results: HLA gene family were identified as central nodes of the analyzed network. Based on action map finding, activation is prominent action and IRF9 was the potent activator. The role of the IRF gene family was highlighted by action map analysis. Conclusion: Regulation of the immune system by HLA and IRF genes family is a crucial factor in the prevention of OM in the studied patients.
Renal replacement therapy in patients with familial Mediterranean fever
Authors: Bashardoust Bahman , Bashardoust Bahram , Ghavami Maryam , Shami Nasrin
Published: November 2021

One of the causes of end-stage renal disease (ESRD) in some countries is the renal involvement caused by the complications of the familial Mediterranean fever (FMF). Amyloidosis is of the most important complications of FMF that can lead to ESRD. We report our experiences of FMF patients with ESRD who received hemodialysis and kidney transplantation over the past 17 years. Of nine patients, four had amyloidosis, two had focal segmental glomerulosclerosis (FSGS), one had IgA nephropathy, and two did not undergo biopsy because their kidneys were atrophic. Of the nine patients, one died of amyloidosis. Seven patients had kidney transplantation and one patient is currently undergoing dialysis. Six patients were transplanted from a living donor and one from a cadaver. The ultrasound examination revealed that five patients had bilateral kidney atrophy, four patients had normal size kidney with amyloidosis. None of the seven patients who underwent renal transplantation had a history of rejection. Kidney transplantation and hemodialysis in patients with FMF is similar to those with other ESRD etiologies.
EDİNİLMİŞ MALLARA KATILMA REJİMİNİN SÖZLEŞMEYLE BAŞKA BİR MAL REJİMİNİN KABULÜ İLE SONA ERMESİ HÂLİNDE ARTIK DEĞERE KATILMA ESASINI DEĞİŞTİREN ANLAŞMALARIN GEÇERLİLİĞİ
Authors: GÜVENÇ Özgür , YAZICI Ayşe Nur Merve
Published: November 2021

Edinilmiş mallara katılma rejiminde eşler, TMK m. 237/I uyarınca, bir mal rejimi sözleşmesi akdederek artık değere katılma esasını değiştirebilirler. Fakat TMK m. 238’de, mal rejiminin boşanma, evliliğin iptali veya mahkeme kararıyla mal ayrılığına geçiş yoluyla sona ermesi hâlinde, eşler tarafından açıkça aksi kararlaştırılmadığı sürece, anlaşmanın uygulanmayacağı düzenlenmiştir. TMK m. 238’in amacı, katılma esasını değiştiren anlaşmayla diğer eşe kazandırmada bulunan eşin farazî iradesinden doğan menfaatinin korunmasıdır. Bu farazî irade, mal rejiminin arzulanmayan, olağandışı sebeplerle sona ermesi hâlinde, anlaşmanın geçersiz olması yönündedir. Sözleşmeyle başka bir mal rejiminin kabulü ise, olağandışı ya da arzulanmayan bir sona erme sebebi teşkil etmediğinden, anılan ihtimalde TMK m. 238’in kıyasen uygulanmasını gerektiren bir farazî iradenin mevcudiyetinden söz edilemez. Dolayısıyla, sözleşmeyle başka bir mal rejimine geçiş hâlinde artık değere katılma oranını değiştiren anlaşmalar kural olarak geçerliliğini korur.
ALMAN HUKUKUNDA YAĞMA BENZERİ HIRSIZLIK SUÇU IŞIĞINDA TÜRK HUKUKUNDA HIRSIZLIK VE YAĞMA SUÇLARININ TAMAMLANMA VE SONA ERME ZAMANLARININ TESPİTİ
Authors: YAŞAR Ercan
Published: November 2021

Bu çalışma ile öncelikle Alman Ceza Kanunu’nun 252. maddesinde düzenlenmiş olan yağma benzeri hırsızlık suçu ele alınacaktır. Akabinde 765 sayılı TCK’nın 495. maddesinin 2. fıkrasında yer verilen ancak 5237 s. TCK’ya alınmamış olan yağma benzeri hırsızlık düzenlemesine kısaca yer verilip, ACK m. 252 ile 765. s. TCK m. 495/2 düzenlemelerinin barındırdığı kıstaslar çerçevesinde Türk hukukunda hırsızlık ve yağma suçlarının tamamlanma ve sona erme anları tespit edilecek ve yağma benzeri hırsızlık suçuna dönüşen fiillerin Türk hukukunda nasıl değerlendirilmesi gerektiği konusunda görüş bildirilecektir. Suçun tamamlanması ve sona ermesi zamanlarının gönüllü vazgeçme ve etkin pişmanlık bağlamında etkileri söz konusu olduğundan benzer olaylar üzerinden bu hususlara açıklık getirilmeye çalışılacaktır.
IOT MODEL WITH MULTIMODAL NODE ALLOCATION AND THE METHOD OF USING MOBILE HEAD NODES FOR DATA COLLECTION
Authors: ВОРОБЬЕВА Д.М. , ПАРАМОНОВ А.И. , КУЧЕРЯВЫЙ А.Е.
Published: October 2021

Рассмотрена задача организации движения головных узлов (ГУ) в сети интернета вещей (ИВ) при неоднородном (мультимодальном) распределении узлов в зоне обслуживания. Предложен метод кластеризации неоднородной сети, позволяющий выделить кластеры (отличающиеся плотностью узлов) и выбирать скорость движения ГУ в соответствии с плотностью в каждом кластере. Метод основан на использовании алгоритма кластеризации DBSCAN, позволяет повысить эффективность использования подвижных ГУ и может быть применен при организации сбора данных в сети ИВ.

The paper is devoted to the problem of organizing the movement of head nodes in the Internet of Things (IoT) network with a heterogeneous (multimodal) distribution of nodes in the service area. A method for clustering a heterogeneous network is proposed, which makes it possible to distinguish clusters that differ in the density of nodes and select the speed of movement of the head node in accordance with the density in each cluster. The proposed method is based on the use of the DBSCAN clustering algorithm and makes it possible to increase the efficiency of the use of mobile head nodes. The method can be applied in organizing data collection in the IoT network.
APPLICATION OF CYCLOSTATIONARY PROPERTIES OF PERIODIC SIGNALS FOR POWER ANALYSIS IN ELECTRIC CIRCUITS
Authors: ШЕВГУНОВ Т.Я. , ГУЩИНА О.А.
Published: October 2021

Предложен циклостационарный подход к анализу мощности электрических цепей, возбуждаемых источниками периодических токов и напряжений. Получены теоретические выражения для характеристик мгновенной мощности на основе взаимной спектральной ковариационной функции и показана их связь со средней и полной мощностью. Проведен анализ гармонического распределения мощности в линейной цепи при периодическом воздействии. На примере численного расчета резонансной цепи продемонстрированы этапы циклостационарного анализа и получены основные характеристики мощности.

The paper proposes a cyclostationary approach to the power analysis for electric circuits excited by sources of periodic currentsorvoltages.Theformalexpressions forcharacteristics of instantaneous power are obtained on the basis of cross spectral covariance function and their relation to the average and apparent power is established. The analysis of the harmonic distribution of the power in a linear circuit under periodic excitation is carried out. The main stages of the method are illustrated with a numerical simulation example.
SAMPLE CLOCK OFFSET COMPENSATION IN THE FIFTH-GENERATION NEW RADIO UPLINK
Authors: ПОНОМАРЕВ О.Г. , АСАФ М.
Published: October 2021

Рассмотрена проблема коррекции искажений OFDM-сигнала, вызванных смещением частоты дискретизации сигнала в приемном и передающем устройствах системы сотовой связи пятого поколения. Предлагаемый метод компенсации смещения частоты дискретизации основывается на прямой коррекции искажений, вносимых в передаваемый сигнал наличием смещения, и не предполагает какой-либо оценки величины смещения. Метод предназначен для коррекции сигналов в восходящем канале системы сотовой связи пятого поколения и основывается на использовании референсных сигналов, рекомендованных стандартами 3GPP. Результаты численного моделирования показали, что использование предлагаемого метода позволяет повысить эффективность передачи данных по многолучевому радиоканалу более чем на 15% в широком диапазоне значений отношения сигнал/шум.

5G-NR, CP-OFDM, synchronization, sample clock offset, PUSCH. О The paper investigates the issue of sampling clock offset ( SCO) in the fifth generation new radio systems. Due to the imperfect SCO estimation methods, the correction methods relying on the SCO estimation are not perfect, so the proposed method directly corrects the effect of SCO without using any kind of estimation method. Our method is designed to correct the signals in the physical uplink shared channel (PUSCH). The method uses reference signals as recommended by the 3rd generation partnership project (3GPP) standards. The results of the numerical simulation show that the use of the proposed method increases the efficiency of data transmission over the multipath radio channel by more than 15% in a wide range of signal-to-noise ratio values.
“Los vegetales que viven en la República”. El estudio de la flora uruguaya en Anales del Museo Nacional de Montevideo, 1894-1925
Authors: Vega y Ortega Baez Rodrigo Antonio
Published: November 2021

Entre 1894 y 1925, Anales del Museo Nacional de Montevideo publicó veintiséis escritos botánicos de la autoría de diez autores, algunos residentes en el Uruguay y otros en el extranjero. El objetivo del artículo es caracterizar las prácticas botánicas desarrolladas por los autores vinculados con el Museo en cuanto a la elaboración del inventario de la flora uruguaya. Los temas en que se divide el artículo son la colecta botánica en las excursiones; el estudio, descripción y clasificación de las especies en el Museo; la práctica experimental en las instituciones científicas de Montevideo; y la utilidad de algunas plantas uruguayas. Los cuatro temas muestran las prácticas científicas que llevaron a cabo los autores al estudiar la flora del país, así como que la revista fungió como un medio impreso que hace evidente la coproducción de conocimiento científico entre diferentes especialistas en la naturaleza del Uruguay ubicados en varias partes del mundo.
Diagnóstico de trastornos funcionales motores agudos a través de la semiología.
Authors: Videla Pablo Agustín , Ferri María Eugenia , Tavolini Darío
Published: November 2021

Los trastornos neurológicos funcionales (TNF) motores se refieren al conjunto de manifestaciones en el movimiento y la fuerza que presentan inconsistencia interna e incongruencia con cualquier enfermedad neurológica descrita. Objetivo: evaluar la utilidad de maniobras semiológicas, en un escenario de urgencia, para demostrar inconsistencia motora. Se evaluaron 31 pacientes con debilidad de algún miembro de menos de 72 horas de evolución, que consultaron al servicio de urgencias de un efector público. Se aplicaron 6 maniobras descriptas en la bibliografía enfrentándose con el diagnóstico del servicio de neurología. Se administraron escalas validadas para el tamizaje de trastornos anímicos. De los pacientes reclutados, 16 fueron diagnosticados como TNF y el resto como orgánicos. No hubo diferencias demográficas significativas. Los signos que demostraron asociarse al diagnóstico de TNF (p<0,01) con alta sensibilidad y especificidad fueron: caída sin pronación, “Spinal Injuries Center (SIC) Test”, signo de Hoover y signo de abducción de la cadera. La presencia de al menos dos signos positivos demostró mejorar su especificidad sin menoscabo de la sensibilidad. Se encontró, además, una asociación contundente entre el diagnóstico de TNF y la presencia de síntomas depresivos así como de estresor psicológico agudo. En conclusión, cuatro de las maniobras evaluadas mostraron utilidad a la hora de definir la etiología de un foco motor. Consideramos que los resultados jerarquizan el examen físico del especialista al evaluar una paresia aguda. Además, la suma de hallazgos significativos colabora en la conformación de un perfil distintivo.
Actualización sobre el uso de estándares de crecimiento de la Organización Mundial de la Salud en la red de atención primaria de Rosario.
Authors: Blanco Virginia I. , Sguassero Yanina , Harvey Guillermina B.
Published: November 2021

Objetivo: a más de 10 años del cambio del patrón de referencia del crecimiento infantil en argentina, se realizó un estudio para conocer el estado de implementación de los estándares de crecimiento de 0 a 5 años de la organización mundial de la salud en atención primaria de la salud. Métodos: estudio transversal realizado en la ciudad de rosario, santa fe (mayo 2018—mayo 2019). Se enviaron encuestas en línea a médicos pediatras y generalistas, y se entrevistaron a informantes clave. Los ejes de indagación fueron: valoración de la herramienta, estrategias de capacitación, e intervenciones para promover el uso e interpretación. El análisis fue cuali—cuantitativo. Resultados: se completaron 95 encuestas y se realizaron ocho entrevistas. La adopción de los estándares oms fue considerado un cambio favorable para la argentina. Las intervenciones de valoradas como de mayor utilidad para optimizar el uso de los estándares de la organización mundial de la salud por los médicos encuestados fueron: mantenimiento de los equipos para mediciones antropométricas, promoción de consejería nutricional e impresión de gráficas de crecimiento para uso individual. Las diferencias de opinión entre los médicos de los centros de salud y quienes ocupan un cargo en gestión estuvieron dadas por la factibilidad de algunas intervenciones en atención primaria de la salud. Conclusión: existen estrategias tendientes a favorecer la implementación de intervenciones valoradas por los médicos de la red de atención primaria que permitirían un mayor aprovechamiento de los estándares de la organización mundial de la salud.
Design and development of experimental models for textile structures
integrated in wound dressings applied in curative therapy of inflammatory
skin diseases, using specific instruments of descriptive statistics
Authors: MIHAI CARMEN , GROSU CRISTINA , CHIRILA LAURA , OLARU SABINA , POPESCU ALINA
Published: October 2021

Wound dressing is a key factor of the wound management system, having as main objective the stimulation of the
healing process for a variety of inflammatory skin diseases. To maximize the therapeutic effects, innovative medical
devices with integrated drug delivery system become of real interest during the last decade. For the realization of the
optimal woven fabrics used as a substrate for various active principles, such as propolis and cinnamon essential oil, the
multivariate linear regression analysis was used to elaborate the conceptual models on the basis of which the
experimental models of the textile supports were designed. Using as input data the characteristics of the selected yarns
(breaking force, elongation at break, torsion/twist, hygroscopicity), one can predict the structural parameters of the
woven fabrics (raw materials, yarn density, lengths of the underlaps) and also the assembly and adjusting parameters
for the machinery from weaving preparation and weaving sectors (advance and height of the drum, reed width,
drawing-in, input/output of the gripper, cross unevenness reed, stationary in maximum open lease, the moment of the
grippers opening, impulse time, the moment of the shaft smoothening, etc.). The validation of the elaborated conceptual
models it was confirmed by the registered yields in the range of 88–96 %, during the weaving process
CLOTHES DEVELOPMENT BASED ON METHODS OF HANDLING
OF PREMATURE BABIES IN THE INTENSIVE CARE UNIT
Authors: Danila V. , Curteza A. , Balan S.
Published: October 2021

The health of children born prematurely remains a significant challenge, but clothing products
designed considering medical requirements and handling methods used in the intensive care unit, may
contribute to the reduction of neonatal mortality. Assistants in the therapy unit implement practices based on
the needs of vulnerable infants, from the very first second of life.
This pilot clinical study was conducted in a specialised on neonatal intensive care unit, at the IMSP Municipal
Clinical Hospital Gheorghe Paladi from Chisinau. Informed consent of parents and/or careers was required.
All users (nurses and doctors) were informed about the product and instructed regarding dressing and
undressing process. This controlled study was conducted under the supervision of doctors and nurses. As the
study was exploratory in nature, aspects of grounded theory have been used for qualitative data collection.
The sample studied consists of preterm infants less than 30 weeks GA, admitted by UTIN in 2018. The
population eligible for qualitative data collection was made up of neonatology nurses from the clinic. To
obtain a heterogeneous sample, aspects such as age, work experience, environment, and education were
considered. The method of observation and subsequent testing used of the newly designed products and every
manipulation under medical conditions was intensely studied. Local reactions, if any, due to the texture and
quality of the textile material that come into contact with the baby's skin, were also carefully monitored. The
process of dressing and stripping off the products, carrying out medical manipulations (in case of neonatal
emergencies), were also carefully observed for developing ease of use clothes.