bluuebunny/crossref_metadata_2025 huggingface dataset:
Promosi Kesehatan Mata melaui Kegiatan Skrining Mata pada Siswa SMP di Kecamatan Wedung, Demak
Authors: Cahyo Wulandari  , Rahmafari Fikra Maulida  , Muhammad Asyam Fawwaz Akbar  , Abdurrahman Nur Prasetyo
Published: June 2024

Mata memegang peran penting dalam hidup seorang siswa. Bila terjadi gangguan pada mata, bisa terjadi penurunan ketajaman penglihatan, yang dapat berdampak pada kualitas hidup siswa. Hal ini bisa ditandai dengan mata buram saat melihat papan tulis atau melihat jauh. Aktivitas siswa seringkali melibatkan kegiatan yang mengharuskan berlama-lama menatap objek dekat, seperti membaca, mengerjakan tugas, maupun menggunakan gawai seperti telepon pintar dan laptop. Tanpa disadari, kebiasaan-kebiasaan tersebut menjadi faktor risiko seorang siswa mengalami gangguan refraksi berupa miopi, atau rabun jauh. Siswa yang mengalami miopi seringkali tidak menyadarinya, sehingga sebagai upaya menjaga kesehatan mata perlu dilakukan skrining mata untuk mengetahui apakah siswa mengalami gangguan refraksi atau tidak, tak terkecuali di Kecamatan Wedung yang menjadi lokasi KKN-PPM UGM unit JT-133. Dalam rangka melaksanakan pengabdian masyarakat, dilakukan skrining mata pada siswa SMP.  Berlokasi di 4 SMP di Kecamatan Wedung, dilakukan pengukuran ketajaman penglihatan (visus) dengan snellen chart. Jumlah yang diperiksa yakni 300 siswa, 55 diantaranya mengalami penurunan ketajaman penglihatan. Setiap selesai pemeriksaan, dilakukan edukasi terhadap siswa tentang cara menjaga kesehatan mata. Pada siswa dengan penurunan ketajaman penglihatan, dilakukan penggalian faktor risiko. Artikel ini disusun untuk menggambarkan bagaimana jalannya skrining kesehatan mata serta kondisi penurunan ketajaman penglihatan beberapa siswa SMP, dan faktor risiko yang mungkin menjadi penyebab gangguan refraksi. Metode yang dilakukan untuk pengumpulan data yakni mendata hasil pemeriksaan visus tiap sekolah dan anamnesis singkat setelah pemeriksaan. Hasil pemeriksaan visus dianalisis dengan metode kuantitatif deskriptif, sedangkan data wawancara dianalisis menggunakan metode kualitatif. Skrining mata pada siswa SMP diharapkan dapat menjadi alat promosi kesehatan baik bagi siswa dengan kelainan refraksi maupun yang tidak, sebagai pengingat untuk menjaga kesehatan mata mereka. Bagi siswa dengan kelainan refraksi, skrining bisa menjadi awal untuk pemeriksaan selanjutnya agar siswa mendapatkan penanganan segera, bisa berupa koreksi refraksi dengan penggunaan kacamata, agar gangguan refraksi yang terjadi tidak berprogresi ke arah yang lebih buruk.
Pengembangan dan Pelatihan Sistem Pengukuran Antropometri Digital kepada Kader Posyandu sebagai Upaya Peningkatan Pelayanan Posyandu Balita dan Pencegahan Dini Stunting
Authors: Sentagi Sesotya Utami  , Aji Nurohman  , Jujun Mulyana  , Tiara Kus Anindita Maharani  , Nadine Mutiara Wibowo  , Jeihan Vitriashiila Maharani  , Izzah Marisa Tasallia  , Annisa Maulidina  , Salsabila Aulia Rahmadani
Published: June 2024

Pertumbuhan dan perkembangan balita merupakan cerminan kesehatan generasi mendatang. Untuk mencegah terjadinya stunting, pelayanan posyandu menjadi sangat penting dalam memantau pertumbuhan anak secara berkala. Kementerian Kesehatan telah mengupayakan penerapan alat antropometri digital di posyandu, tetapi dalam praktiknya, sebagian besar kader masih mengandalkan pencatatan manual karena kesulitan dalam menggunakan antropometri digital dari pemerintah. Sistem antropometri digital ini dirancang untuk memberikan solusi yang lebih akurat dalam mengukur pertumbuhan balita. Berbeda dari antropometri digital yang telah ada, sistem ini juga terintegrasi dengan aplikasi yang intuitif sehingga memudahkan kader saat melakukan pengukuran. Selain fungsi pengukuran, sistem antropometri digital ini dilengkapi dengan dashboard kesehatan yang berguna untuk memberikan pandangan komprehensif terhadap status pertumbuhan balita dan secara otomatis menghasilkan grafik analisis. Dengan demikian, petugas kesehatan dapat dengan cepat mengidentifikasi anak yang berpotensi stunting dan mengambil tindakan dini. Kegiatan pengabdian masyarakat ini bertujuan untuk mengembangkan dan melatih penggunaan sistem pengukuran antropometri digital kepada kader posyandu di Desa Karangsari dan Desa Sarwodadi. Pengabdian ini dilakukan dengan metode pelatihan berbasis Focus Group Discussion (FGD) kepada para kader posyandu. Selanjutnya, metode evalusi penggunaan sistem antropometri digital dilakukan melalui System Usability Scale (SUS) yang menggunakan sepuluh pernyataan sebagai tolok ukur penggunaan sistem antropometri digital ini. Dari hasil pengujian menggunakan System Usability Scale (SUS), diperoleh skor akhir sebesar 56,58 yang mengindikasikan rating tingkat kelayakan "OK". Hasil ini menunjukkan bahwa sistem antropometri digital ini sudah dapat digunakan dengan baik, tetapi para kader posyandu masih tetap memerlukan pendampingan dari bidan desa yang sudah memahami cara penggunaan sistem ini.
Assessing the Efficacy of Language Assessment Tools in Educational Settings
Authors: ABIMBOLA PHD AKINKUOTU, FOLUKE , SIMEON FOWOWE, SUNDAY , OMOWUMI PHD ADEBANJO, MOPELOLA
Published: June 2024

Language assessment plays a pivotal role in evaluating learners’ language proficiency and informing educational practices. This paper provides a comprehensive review of international standards guiding the assessment of language proficiency in educational settings. Drawing upon established frameworks such as the Common European Framework of Reference for Languages (CEFR) and the American Council on the Teaching of Foreign Languages (ACTFL) proficiency guidelines, this review examines the key principles, methodologies, and criteria for assessing the efficacy of language assessment tools. It explores the importance of validity, reliability, authenticity, and practicality in the design and implementation of language assessment instruments. Furthermore, it discusses the significance of considering socio-cultural and contextual factors in ensuring the fairness and equity of language assessment practices. The review also highlights emerging trends and challenges in language assessment, including the integration of technology and the need for continuous professional development for assessors. By synthesizing international standards and best practices, this paper offers valuable insights for educators, assessment specialists, and policymakers striving to enhance the quality and effectiveness of language assessment in educational contexts.
A Study on the Current Situation of English Teaching in Compulsory Education and Countermeasures
Authors: Li Xiaoling , Feng Zhenxi
Published: June 2024

The purpose of this paper is to study the current situation and existing problems of English teaching in China's compulsory education stage, and to propose corresponding countermeasures. By analysing the current syllabus, curriculum, teaching objectives and contents, teaching methods and means, teaching evaluation and feedback, this paper finds that there are problems such as insufficient students’ interest in learning, teachers’ professional qualities and teaching abilities need to be improved, uneven distribution of educational resources, and high social and parental expectations of English education. Aiming at these problems, this paper puts forward countermeasure suggestions such as optimising curriculum and teaching content, improving teaching methods and means, improving teacher training and quality enhancement, strengthening the integration and distribution of educational resources, and adjusting social and parental expectations of education. It is hoped that the research in this paper can provide certain reference and learnings for the reform of English education in China’s compulsory education stage.
El centro de la ciudad capital del estado de Chiapas y su historia fragmentada
Authors: Tondopó Mendoza Yonalli
Published: June 2024

Los centros históricos son espacios que normalmente concentran edificaciones de diferentes etapas arquitectónicas de la ciudad, sin embargo, en ocasiones no siempre se resguardan la mayoría de estos. El caso del centro histórico de Tuxtla Gutiérrez, Chiapas, es uno de este tipo, pues al cambiar constantemente su imagen urbana, a simple vista no parece ser un sitio con historia por no haber conservado sus bienes monumentales. Sin embargo, mediante una narración cronológica de los acontecimientos más relevantes de este lugar se hará énfasis en que esta zona contiene historia y por lo tanto debe ser reconocido como tal.
POCUS en el paciente trasplantado renal para un diagnóstico temprano de hidronefrosis: casos clínicos y revisión de literatura
Authors: Anaya-Taboada Marco , Palacio-Echeverri Laura , Sanabria-Giraldo Valeria , Lozano-Suárez Nicolás , Gómez-Montero Andrea , García López Andrea , Girón-Luque Fernando
Published: June 2024

Introducción: el ultrasonido en el punto de atención (POCUS, según las siglas en inglés para point-of-care ultrasound) es una herramienta rápida y fácil de usar que permite correlacionar la anamnesis con hallazgos ecográficos. Ha tomado fuerza en distintos campos de la práctica médica y en nefrología ha sido utilizado para pacientes con enfermedad renal crónica, evidenciando alteraciones anatómicas y vasculares; aun así, se dispone de poca literatura sobre su utilización en pacientes trasplantados renales.
Objetivo: exponer cómo el POCUS fue utilizado en una serie de pacientes de Colombiana de Trasplantes y el impacto en sus desenlaces clínicos, correlacionando los hallazgos con una revisión de la literatura actual.
Presentación del caso: se reportaron tres casos de pacientes trasplantados renales en seguimiento por Nefrología, en quienes se utilizó POCUS para su valoración postrasplante, evidenciando hidronefrosis. Ante este hallazgo, se solicitó confirmación imagenológica por radiología con ecografía o pielografía y se indicó un tratamiento oportuno de derivación de las vías urinarias. En el seguimiento posterior al manejo, los pacientes presentaron una adecuada evolución clínica y de su función renal.
Discusión y conclusión: los casos presentados soportan el beneficio del POCUS en el seguimiento de pacientes trasplantados, permitiendo una identificación y un manejo oportuno de hidronefrosis. Se considera que este estudio puede ser un primer paso en la utilización de esta herramienta de rutina en el seguimiento de esta población, pero aun así se hace énfasis en la necesidad de estudios con mayor tamaño de muestra que incluyan diferentes hallazgos ecográficos.
Textual connections of the mythonyms in I.A. Bunin’s poetry
Authors: Selemeneva Olga A.
Published: June 2024

The question of the textual functioning of mythonyms in the poetic heritage of I.A. Bunin is raised. The relevance of the topic is due to the interest of linguists in the problem of artistic text-building, in particular the author’s preference in vocabulary selection, as well as the unresolved issue of modeling Bunin’s onomasticon. The purpose of the study is to describe the textual connections of mythological names, through which meaningful and conceptual information is explicated and a subtext is formed. The research material included the scientific edition (by Professor T.M. Dvinyatina) of I.A. Bunin’s poetry, from which 272 units were extracted by continuous sampling. The factual material was systematized and interpreted with the descriptive, taxonomic, quantitative methods, contextual analysis, modeling. Standing out against the background of different layers of the Bunin’s vocabulary, mythological names interact with each other, with other semantic subgroups of onyms, appellatives, attributive and verbal vocabulary. The author notes that mythoanthroponyms and theonyms have the richest syntagmatic connections. Contextual synonymy is found in demononyms, mythoanthroponyms, mythopersonyms, mythoponyms and theonyms; and contextual antonymy is found in mythoponyms and mythopersonyms. The intertextual nature and the precedent level determine the associative connections of Bunin’s mythonymicon units. It is concluded that the textual functioning of mythonyms is determined by I.A. Bunin’s intention to overcome the particularization of cultural worlds and create such an individual author’s mythopoetic space where images and plots already familiar to readers are constantly enriched with new meanings. The prospects of the work include the study of Bunin’s prose mythonymicon and the textual connections of mythonyms in it, which will allow to create a consistent onomastic model of Bunin-writer.
Educating future Russian language teachers in the United States
Authors: Reagan Timothy G.
Published: June 2024

The increasing tensions between the Russian Federation and the United States of America have exacerbated the already serious decline in numbers of students seeking to study Russian, as well as the concomitant elimination of many Russian language programs at both the K-12 and university levels. The purpose of the research is to consider the need to improve the preparation and quality of future teachers of Russian in U.S. public schools. This work draws on applied philosophical analysis and policy studies, as well as a review of existing Russian language and literature programs at major U.S. universities. Measures of relevant data are presented, showing a paucity of linguistic competence in Russian produced through current practice in the U.S. Implementation is suggested. A model five-year program is proposed for the preparation of future Russian language teachers in the United States. Based on the typical undergraduate curriculum, this model would involve coursework in three broad areas: general education courses (the liberal arts and sciences), Russian language and related courses, and courses concerned with pedagogy.
Folk orthology in the digital environment
Authors: Likhachev Sergei V. , Popova Elena I.
Published: June 2024

In the digital era, folk orthologs (language normalizers who are not professional in the quality of speech, the choice of criteria, and the codified norm) have received unlimited access to the electronic publication of their opinions, which has come to the attention of scientists. The relevance of the proposed topic is determined by the need to popularize traditional cultural values, in particular, knowledge of the Russian language. The purpose of the study is to find out the motives of folk orthologs and the norm criteria used in their rulemaking, degree of objectivity, the correspondence of their opinions to scientific ideas and the level of literacy in their statements. The research material was based on judgments about the language of non-professional linguists available at online forums (public dialogues) about the Russian language. The method of content analysis was used, including the search and selection of judgments of folk orthologs, as well as the analysis of linguistic material from the perspective of compliance with norms in linguistic dictionaries. The results of the study showed both the lack of knowledge of folk orthologs about the Russian language and their demand for this knowledge. The motives for their activities were identified - interest in the language and its protection, self-realization, leisure time, and also the main areas of activity of folk orthologs - rulemaking, and the search for norms in spelling, vocabulary and grammar. This knowledge made it possible to propose recommendations for a possible dialogue between scientists and folk orthologs.
BENEFÍCIOS E DIFICULDADES NA UTILIZAÇÃO DA CONTABILIDADE AMBIENTAL: REVISÃO SISTEMÁTICA DA LITERATURA NO BRASIL
Authors: Paula Débora Daiana de , Rosa Maria Clair da , Feil Alexandre André
Published: June 2024

A contabilidade ambiental fornece informações aos stakeholders sobre eventos ambientais por meio de relatórios e notas explicativas com uma visão mais clara sobre as ações na redução dos impactos ambientais e melhora da sustentabilidade ambiental. Neste sentido, este estudo objetivou a realização de uma revisão sistemática da literatura para análise dos benefícios e das dificuldades na aplicação da contabilidade ambiental no Brasil. A abordagem vincula-se a qualiquantitativa, descritiva e o procedimento técnico consiste na revisão sistemática da literatura. Nesta revisão sistemática utilizou-se as palavras-chave por meio dos operadores boleanos (“contabilidade ambiental” AND “benefícios” AND “dificuldades” OR “desvantagens” OR “vantagens”) aplicado na base de periódicos do Google Scholar, na qual foram selecionados 20 artigos científicos. Os resultados revelam um número de publicações estável de 2012 a 2023; os autores são distintos nas publicações; os estudos de caso foram nas indústrias em geral e de grande porte localizadas na região sudeste e sul do brasil; e o Qualis/CAPES no estrato inferior (B e C). Os benefícios da contabilidade ambiental com maior frequência vinculam-se a imagem organizacional, redução de multas e indenizações ambientais, auxilia na tomada de decisão, entre outros. As dificuldades relacionam-se a identificação, mensuração e reconhecimento dos fatos contábeis ambientais, elevados gastos, falta de profissionais qualificados, entre outros. Conclui-se que os artigos científicos que exploram a temática dos benefícios e dificuldades na contabilidade ambiental são incipientes. Os benefícios e as dificuldades com maior frequência retratam a realidade da utilização da contabilidade ambiental nas organizações brasileiras.
Analisis Keterlaksanaan Pendekatan Experiential Learning dan Pengaruhnya Terhadap Keterampilan Proses Sains Siswa pada Materi Ikatan Kimia di Kelas X MIA SMAN 1 Kota Jambi
Authors: Dewi Fatria , Afrida Afrida , Efrianto Bayu
Published: June 2024

Keterlakasanaan pendekatan experiential learning oleh guru memiliki persentase sebesar 79,17% dikategorikan baik, persentase pendekatan oleh siswa sebesar 76,68% dikategorikan baik, dan persentase keterampilan proses sains siswa sebesar 71,95% dikategorikan baik. Hubungan keterlaksanaan pendekatan experiential learning dengan keterampilan proses sains siswa diperoleh rxy = 0,78973 dengan tingkat hubungan kuat. Uji signifikansi dilakukan dengan uji t dengan diperoleh thitung>ttabel (6,812018 > 2,048) dengan dk = 28 dan Î± = 0.05, sehingga H0 ditolak dan Ha diterima. Berdasarkan hasil penelitian bahwa keterlaksanan pendekatan experiential learning berjalan dengan baik serta terdapat pengaruh keterlaksanaan pendekatan experiential learning terhadap keterampilan proses sains siswa pada materi ikatan kimia di kelas X MIA 3 SMAN 1 Kota Jambi.
Essays on Design Science in Management and Marketing
Authors:   , Micu Daniela
Published: June 2024

This thesis explores design science in management and marketing, with a focus on how to expand the research approach from the field of management to that of marketing specifically. Design science is a pragmatic problem-solving approach that provides the researcher with the means to develop artifacts that improve future outcomes. This cross-disciplinary study scopes the allied field of management and proceeds to answer the research question: How can marketing use design science? The thesis employs a systematic literature review, a bibliometric co-citation analysis and conceptual development. Key findings: 1. Purpose of design science: A systematic literature review reveals that design science is presently used in empirical articles to support researchers to evidence the development of an artifact, often related to technology. 2. Norms: The study explores how design science is used by researchers in empirical articles, in the allied field of management. Our findings indicate that design science can be used as a research method, employing a well-known theoretical process or framework, or alternatively as a paradigm on its own. 3. Mapping: Examining the progress over time, a visualization of the various streams of research in design science is presented, by employing a bibliometric co-citation analysis. Findings suggest that the design science literature is segmented, however still concentrated around Information Systems authors. 4. Positioning: This thesis assesses the positioning of design science and suggests some options that may prove useful for marketing. First, critical realism philosophy of science aligns well with the pragmatism of design science; a second direction is seeing design science as a new paradigm, a new lens to understand the world. 5. Exemplifying: Using a conceptual paper as an example, this PhD thesis explores how marketing can use design science. As a paradigm, a new lens, design science can help advance research in problematic areas, such as conceptualizing value creation in digital platforms. Implications for future research and marketing: This PhD thesis not only contributes to the management and the emerging stream of design research in the field of marketing by exploring how this approach is presently used, but also provides guidelines, propositions, and research agendas to guide future research. Such avenues include the exploration of using design science in essential areas of marketing such as consumer research and developing marketing-led conceptual works for design science, design artifact or operationalization of kernel theory. Conclusion: In conclusion, this study underlines the importance of having a problem-solving approach to research when dealing with today’s challenges for marketing, design science being ideally positioned to increase collaborations and drive innovation. By developing design science grounding, this PhD thesis offers valuable guidance for future research seeking to find solutions to the increased demands of marketing practitioners, policymakers, and society at large.
A neural-mast cell axis regulates skin microcirculation in diabetes
Authors: Li Xinran , Yuan Dan , Zhang Peng , Luo Chenglei , Xie Xinyang , Zhang Yue , Wei Zhengqi , Wang Mingyang , Cai Yunqiu , Zeng Yi , Lai Luying , Che Delu , Ling Hao , Shi Shengjun , Zhang Hong-Fei , Wang Fang , Li Fengxian
Published: June 2024

Abstract

Changes in microcirculation lead to the progression of organ pathology in diabetes. Although neuroimmune interactions contribute to a variety of conditions, it is still unclear whether abnormal neural activities affect microcirculation related to diabetes. Using laser speckle contrast imaging, we examined the skin of patients with type 2 diabetes and found that their microvascular perfusion was significantly compromised. This phenomenon was recapitulated in a high-fat-diet-driven murine model of type 2 diabetes-like disease. In this setting, although both macrophages and mast cells were enriched in the skin, only mast cells and associated degranulation were critically required for the microvascular impairment. Sensory neurons exhibited enhanced TRPV1 activities, which triggered mast cells to degranulate and compromise skin microcirculation. Chemical and genetic ablation of TRPV1+ nociceptors robustly improve skin microcirculation status. Substance P (SP) is a neuropeptide and was elevated in the skin and sensory neurons in the context of type 2 diabetes. Exogenous administration of SP resulted in impaired skin microcirculation, whereas neuronal knockdown of SP dramatically prevented mast cell degranulation and consequently improved skin microcirculation. Overall, our findings indicate a neural-mast cell axis underlying skin microcirculation disturbance in diabetes and shed light on neuroimmune therapeutics for diabetes-related complications.

Article Highlights

· Impaired microcirculation is a shared feature of various complications in type 2 diabetes. Mechanisms underlying its pathology remain not fully understood. Compared to internal organs, the skin is superficial and accessible for microcirculation observation.

· Whether neuroimmune elements play a role in the skin microcirculation impairment associated with type 2 diabetes.

· Sensory neurons are hypersensitized in diabetes and induce overexpression of substance P that triggers mast cell degranulation and consequently impairs skin microcirculation.

· Neuroimmune modulation sheds light on new strategies for treating microcirculation disturbance in type 2 diabetes.
Comparative Evaluation of Antioxidant Activity in Extracts and Fractions from Leaves and Stem of Geophila obvallata (Schumach.) Didr
Authors: LO Iserhienrhien
Published: June 2024

Background: Oxidative stress, a condition characterized by an imbalance between reactive oxygen species (ROS) and antioxidant defences, is increasingly implicated in various human diseases. Medicinal plants with potent antioxidant properties hold promise for therapeutic interventions against oxidative stress-related pathologies. This study aimed to comparatively evaluate the antioxidant potential of leaf and stem extracts and fractions derived from Geophila obvallata. Methods: Methanolic extracts of G. obvallata leaves and stems were subjected to solvent partitioning to obtain fractions based on polarity. Total phenolic content (TPC) and total flavonoid content (TFC) were determined. The antioxidant capacities of the extracts and fractions were assessed using established assays, including hydroxyl radical scavenging (HRSA) and ABTS+ cation radical scavenging. Results: The highest concentrations of phenolics (86.35 and 79.72 mg/g tissue gallic acid equivalents – GAE) and flavonoids (67.56 and 64.92 mg/g tissue quercetin equivalents – QE) were observed in the leaf and stem methanol extracts, respectively. Remarkably, the antioxidant activity of both leaf and stem methanol fractions surpassed that of the standard controls (ascorbic acid, α-tocopherol, and trolox). The antioxidant capacity exhibited a decreasing trend across the various extracts and fractions, following the order: methanol > 1-butanol > chloroform > benzene > ethyl acetate > n-hexane > aqueous. These findings suggest superior free radical scavenging abilities in the leaf extracts and fractions compared to the controls.Conclusion: This investigation unveils the significant antioxidant potential of G. obvallata leaf extracts, highlighting their potential efficacy in combating diseases associated with oxidative stress. These findings warrant further exploration to elucidate the underlying mechanisms of action and validate their therapeutic potential in vivo models.
Pentahelix Stakeholder Synergy in a Public Communication Perspective to Realize Digital Tourism
Authors: Helmi Rahmadhona Fitri , Nurhabibi Pratiwi , Evelynd Evelynd , Putri Sinta Westika , Ikhlas Al
Published: June 2024

The tourism industry in Indonesia was the second-largest contributor to foreign exchange earnings, which absorbed approximately 10% (13 million workers) of the total national workforce in 2019. However, COVID-19 led to a drastic decline in tourists visiting Indonesia. The number of tourists in West Sumatra Province decreased by more than 50%, while the city of Padang experienced a decrease of more than 75% for foreign and 50% for domestic tourists. To solve this problem, the Padang City Tourism Office devised an alternative solution using digital platforms. The Padang City Tourism Office launched an application called SIDETA (Tourist Destination Information System), which contains information about tourism in Padang. This research aims to investigate how the collaboration between the Padang City Tourism Office and other helix elements contributes to the realization of digital tourism in Padang City and analyze the obstacles and challenges faced by the Padang City Tourism Office in building synergy with other helix elements. This research uses a qualitative and quantitative research approach. Informants and respondents were selected using purposive sampling. Furthermore, three data collection techniques were used: surveys, rapid appraisal, and participatory methods. The results show that 75% of the helix elements in Padang's tourism sector are unaware of the existence of the SIDETA, and 94.2% admit to not being involved in the creation and development of the application.
Imperative Strategy of Digital Transformation: A Case Study of Surabaya City's Digital ID Card Identity
Authors: Dwi Putra Maulana Yogi Aditya , Kriswibowo Arimurti
Published: June 2024

Digitalization is an innovation based on technological advances that can make governance more effective and efficient. This makes human activities carry out digital transformation in both the public and private sectors. One of the implementations of digital transformation in the public sector is the implementation of Digital ID cards. Digital transformation in the context of digital ID cards must be balanced with the readiness of both implementers and the community as policy actors. This research identifies digital transformation in the context of Digital KTP in Surabaya City using the imperative strategy theory of digital transformation model Verhoef which has 4 indicators, namely: Digital Resources, Organizational Structure, Improvement Strategy, and Measures and Goals. Data is obtained through analysis of observation results, documentation, and interviews with implementing agencies and the community. The results of the study found that there was a 25% target non-achievement from the Ministry of Home Affairs of the Republic of Indonesia for the activation of Digital KTP in Surabaya, this was due to a less massive improvement strategy and a lack of public awareness regarding this innovation. This study concludes that there are still indicators that have obstacles such as digital resources, which in its implementation there are still obstacles in the IKD application and growth strategies that still need strategies to reach the elderly and add features to increase the value of innovation to increase public awareness of digital transformation.
Su Dante e la cultura visuale: l’Inferno illustrato da Tom Phillips
Authors: Casadei Alberto
Published: June 2024

Der Aufsatz betrachtet die Illustrationen, die der englische Künstler Tom Phillips (1937–2022) für Dantes Inferno angefertigt hat, das er auch übersetzt hat. Die Analyse zeigt die Bedeutung der allegorischen Wiederverwendung von Bildern und Materialien, die bereits in der Tradition vorhanden sind, gemäß einer ‘postmodernen’ Vorgehensweise, die hier jedoch durch eine sorgfältige Interpretation von Dantes Text untermauert wird. Auf diese Weise erhält man wirklich originelle Interpretationen der verschiedenen dargestellten Gesänge
Multifunktionale und nachhaltige Durchfahrtssperren
Authors: Gebbeken Norbert , Andrae Matthias , van der Woerd Jan Dirk
Published: June 2024

Der Schutz von öffentlichen Plätzen vor Angriffen mit Fahrzeugen, sogenannten Überfahrtaten, ist zu einem wichtigen Bestandteil bei der Planung von Innenstädten geworden. Planer und Planerinnen stehen hierbei vor der besonderen Herausforderung, sichere und lebenswerte Orte zu gestalten. Dabei kommt es häufig zu Zielkonflikten, denn die Errichtung von Durchfahrtssperren an prominenten öffentlichen Plätzen kann im Widerspruch stehen zu Leitbildern in der Stadtentwicklung, die darauf abzielen, eine offene urbane Atmosphäre zu schaffen. Daten zur Eintretenswahrscheinlichkeit von Überfahrtaten im Vergleich zu anderen allgemein akzeptierten Gefahren zeigen, dass die Gefahr, durch Überfahrtaten verletzt oder getötet zu werden, äußerst gering ist. Errichtete Durchfahrtssperren werden somit mit großer Wahrscheinlichkeit während ihrer Lebensdauer ihre Schutzwirkung nie zeigen müssen. Da eine Monofunktionalität in diesem Fall weder sicherheitstechnisch noch ökonomisch sinnvoll ist, plädieren wir für multifunktionale Durchfahrtssperren. Doch welche Kriterien sollten diese erfüllen? Angesichts des Klimawandels befürworten wir „grüne“ und „blaue“ statt „graue“ Durchfahrtssperren. Für die Gestaltung sicherer und lebenswerter Orte eignen sich insbesondere Elemente der Stadtmöblierung sowie der Landschafts- und Gartenarchitektur.
USE OF LEUCINE IN A PATIENT WITH SHWACHMAN-DIAMOND SYNDROME: A CLINICAL CASE
Authors:   National Scientific and Practical Center for Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, Moscow, Russia, Deordieva E.A. , Rostegaev R.S. ,   National Scientific and Practical Center for Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, Moscow, Russia, Shvets O.A. ,   National Scientific and Practical Center for Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, Moscow, Russia, Grishutina A.M. ,   I.M. Sechenov First Moscow State Medical University, Moscow, Russia, Pavlova A.V. ,   National Scientific and Practical Center for Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, Moscow, Russia, Abasov R.Kh. ,   National Scientific and Practical Center for Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, Moscow, Russia, Raikina E.V. ,   National Scientific and Practical Center for Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, Moscow, Russia, Lebedev V.V. ,   Krasnodar Krai Regional Children's Clinical Hospital, Krasnodar, Krasnodar Krai, Russia, Asekretova T.V. ,   Krasnodar Krai Regional Children's Clinical Hospital, Krasnodar, Krasnodar Krai, Russia, Shcherbina A.Yu. ,   National Scientific and Practical Center for Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, Moscow, Russia
Published: June 2024

Schwachman-Diamond syndrome (SDS) is a rare autosomal recessive disease from the group of ribosomopathies characterized by exocrine pancreatic insufficiency, bone marrow dysfunction, malnutrition, protein-energy malnutrition, growth retardation, skeletal abnormalities and a predisposition to the development of myelodysplastic syndrome and acute myeloid leukemia. Severe hematological disorders, a high risk of developing MDS/AML, with a high percentage of unfavorable outcomes, prompted the consideration of alternative routes for the therapy in these circumstances. The possibility for the use of L-leucine, an essential amino acid, as a pathogenetic therapy in patients with severe dyshematopoiesis in SDS by analogy with its use in another ribosomopathy disease, Diamond-Blackfan anemia (DBA), is discussed in the Article.
VACCINATION IN CHILDREN WITH INBORN ERRORS OF IMMUNITY: MODERN SAFETY AND EFFECTIVENESS APPROACHES
Authors:   National Scientific and Practical Center for Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, Moscow, Russia, Musaeva E.Ya. , Dvorkina S.N. ,   “Tigryonok” Children's Medical Center, Moscow, Russia, Deordieva E.A. ,   National Scientific and Practical Center for Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, Moscow, Russia, Shcherbina A.Yu. ,   National Scientific and Practical Center for Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, Moscow, Russia
Published: June 2024

Primary immunodeficiencies (PIDs) or inborn errors of immunity (IEIs) are a heterogeneous group of genetically-determined diseases that are divided into ten groups according to modern classification. The high heterogeneity in clinical manifestations and pathogenetic mechanisms as well as wide use of immunoglobulin replacement therapy, various immunosuppressant and anti-inflammatory drugs make it difficult to decide on the safety and efficacy of vaccination for patients with IEIs. There are no universally accepted recommendations for vaccine prophylaxis among patients with IEIs both in Russia and Worldwide due to the lack of controlled clinical trials available. Authors have attempted summarizing the bibliographical sources available on the safety and efficacy of vaccine prophylaxis in individuals with different forms of IEIs considering the Authors’ own opinion raising the importance of controlled clinical trials.
SYSTEMIC JUVENILE IDIOPATHIC ARTHRITIS, MACROPHAGE ACTIVATION SYNDROME AND CARDIOPULMONARY INVOLVEMENT IN RHEUMATIC DISEASES: A RHEUMATOLOGIST’S MUST-KNOWS
Authors:   Saint Petersburg State Pediatric Medical University, Saint Petersburg, Russia, Belozerov K.E. ,   Saint Petersburg City Children's Polyclinic No. 29, Saint Petersburg, Russia, Kostik M.M. ,   Saint Petersburg State Pediatric Medical University, Saint Petersburg, Russia
Published: June 2024

Systemic juvenile idiopathic arthritis (sJIA) is the most severe variant of JIA that can be characterized by a life-threatening course. sJIA manifests with fever, arthralgia/arthritis, hepatosplenomegaly, leukocytosis and systemic inflammation markers. Macrophage activation syndrome (MAS) is the most severe complication of this disease. This Article represents up-to-date information on pathogeneses of sJIA and MAS, describes approaches to diagnosis, treatment of both uncomplicated and complicated forms of sJIA and refractory variants of the MAS course. Current data regarding the monitoring of sJIA therapy effectiveness and safety is presented as well. Predictors for the most recently discovered, i.e. relatively new “target organs” in patients with sJIA and cardiopulmonary disorders in particular are given.
PHYSIOLOGICAL BASIS OF CARDIONEUROABLATION AND ITS CLINICAL APPLICATION IN CARDIAC ARRHYTHMIAS
Authors:   Research and Clinical Institute of Pediatrics and Pediatric Surgery named after Academician Yuri Veltischev with the Pirogov Russian National Research Medical University, Moscow, Russia, Kovalyov I.A. , Solovyov V.M. ,   Research and Clinical Institute of Pediatrics and Pediatric Surgery named after Academician Yuri Veltischev with the Pirogov Russian National Research Medical University, Moscow, Russia, Egorov L.V. ,   Research and Clinical Institute of Pediatrics and Pediatric Surgery named after Academician Yuri Veltischev with the Pirogov Russian National Research Medical University, Moscow, Russia
Published: June 2024

Increased tone of the parasympathetic part of the autonomic nervous system, affecting the pacemaker cells, may cause sinus bradycardia, develop long pauses of heart rhythm, paroxysmal or permanent atrioventricular block followed by reflex syncope. The usual reflex syncope treatment is conservative and includes avoiding situations that trigger syncope (prolonged standing, sight of blood etc.), tilt-training, adequate drinking regime, wearing compression underwear, sleeping with the head of the bed elevated and in some cases stimulating neuro- and vegetotropic therapy. Some patients are refractory to conventional methods of treatment and retain severe symptoms that worsens quality of their life seriously. These patients may be required a pacemaker implantation subsequently. Cardioneuroablation is an alternative treatment in patients with overactive parasympathetic nervous system that is based on radiofrequency catheter ablation of the major parasympathetic autonomic ganglia around the heart.
CLINICAL CASE OF PYODERMA GANGRENOSUM IN A FEMALE ADOLESCENT
Authors:   Pirogov Russian National Research Medical University, Moscow, Russia, Udzhukhu V.Yu. , Ilyenko L.I. ,   Pirogov Russian National Research Medical University, Moscow, Russia, Gumennaya E.R. ,   Russian Children's Clinical Hospital with the Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia, Moscow, Russia, Botkina A.S. ,   Pirogov Russian National Research Medical University, Moscow, Russia,   Russian Children's Clinical Hospital with the Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia, Moscow, Russia, Kukalo S.V. ,   Pirogov Russian National Research Medical University, Moscow, Russia
Published: June 2024

Pyoderma gangrenosum (PG) is the most severe type of pyoderma and is extremely rare among children and adolescents. Authors represent a clinical case of PG in a 14 years old female adolescent characterized by multiple sharply painful ulcerative defects with a pronounced tendency to peripheral growth. PG had arisen and proceeded further during the postoperative period against the background of iron deficiency anemia, chronic nonspecific nonulcerative colitis and a dysfunctional state of humoral immunity. Making a diagnosis, conducting differential diagnostics, identifying provoking factors, searching for concomitant somatic pathology, using a set of therapeutic measures made possible eliminating the PG clinical manifestations completely though development of the preventive measures and determination of the prognosis of the disease are difficult clinical tasks for pediatric practitioners nowadays.
ATYPICAL HEMOLYTIC-UREMIC SYNDROME IN CHILDREN IN BELARUS AND THE FIRST USE OF COMPLEMENT BLOCKING TREATMENT THERAPIES
Authors:   Belarusian State Medical University, Minsk, Republic of Belarus, Baiko S.V. , Charadnichenka M.D. ,   Belarusian State Medical University, Minsk, Republic of Belarus
Published: June 2024

Atypical hemolytic uremic syndrome (aHUS) is one of the most complex and severe forms of thrombotic microangiopathy with an unfavorable outcome in its natural course. The purpose of this research was to study the epidemiology, demographics, course and outcomes of aHUS in comparison with patients with typical hemolytic uremic syndrome (tHUS) as well as to conduct a personal analysis of all cases of aHUS and evaluate the response to therapy, including comple-ment-blocking with Eculizumab. Materials and methods used: the study was longitudinal, obser-vational and included all 349 cases of HUS in children in Belarus in 2015-2023. A comparative analysis of demographic and clinical data, laboratory results and outcomes was performed in pa-tients with HUS hospitalized at the Center for Pediatric Nephrology and Renal Replacement Therapy of the Republic of Belarus (Minsk, Belarus). Results: of 349 HUS cases, the proportion of aHUS was 3,7% (13). Children with aHUS were older (4,6 (1,6; 6,7) v. 2,7 (1,7; 4,8) y/o with tHUS) due to the portion of patients older than 5 y/o (46%). In aHUS, severe central nervous system disorders were more often observed (62% v. 14%, p=0,002), the development of critical conditions requiring transfer to mechanical ventilation (39% v. 9%, p=0,006), prolonged anuria with the need for dialysis therapy in 100% of cases and severe adverse outcomes (death or end-stage renal disease) during natural course (66,0% v. 2,7%, p<0,001). The most common trigger for aHUS was acute intestinal infections in 54% of cases. A genetic study was performed in 9 (69%) children with aHUS and in 8 (89%) of them the CFHR3/CFHR1 deletions were detected: in 4 cases (3 hetero- and a single homozygous) and heterozygous pathogenic and probably patho-genic gene mutations, CFHR5 in 2 cases, CFH in a single case and combined CD46 and CFI in a single case as well. Antibodies to complement factor H were detected in 5 patients, 3 of which had a CFHR3/CFHR1 deletion. Therapy with a biosimilar of the original Eculizumab showed its effectiveness in aHUS: in 3 (100%) children it was possible to prevent the return of the disease in the kidney graft, in single patient who did not receive prophylaxis it was able to block the recur-rence of aHUS in the transplanted kidney while preserving its function, in 3 (100%) patients with late administration of treatment the urine output was restored after prolonged anuria (24, 33 and 59 days); in a single child with the antibody variant of aHUS, with early administration of the drug, renal function was preserved. No complications of complement blocking therapy were not-ed. Conclusions: the introduction into clinical practice of a biosimilar of the original Eculizumab in children in Belarus has significantly improved the outcomes and prognosis of the disease.
O professor investigador em comunidades de prática
Authors:   Universidade do Porto, Cosme Ariana
Published: June 2024

Recensão crítica da obra de Mestre. L (2023). O professor investigador em comunidades de prática. Gráfica Manuel Barbosa & Filhos, Lda, 281 p.
PERBANDINGAN NILAI TARGET STRENGTH IKAN GABUS (Channa striata) DAN IKAN LELE (Clarias gariepinus)
Authors: Risandes Octa , Brown Arthur , Isnaniah Isnaniah
Published: June 2024

Ikan lele memiliki bentuk tubuh yang lonjong dan ramping, dengan kepala yang relatif besar dan mulut yang lebar dengan kulit halus dan berwarna gelap, cenderung kehitaman atau kebiruan dengan bintik-bintik kecil berwarna putih. Ikan gabus memiliki sisik yang halus dan berwarna abu-abu kehijauan dengan bercak-bercak hitam kecil di bagian punggung dan sisi tubuhnya. Ikan gabus memiliki gelembung renang yang berkembang dengan baik namun ikan lele memiliki gelembung renang yang tidak berkembang. Penelitian bertujuan untuk mengukur nilai Target Strength (TS) ikan lele dan juga ikan gabus berdasarkan panjang dan bobotnya serta membandingkan nilai TS ikan gabus dan ikan lele berdasarkan gelembung renang yang dimiliki menggunakan splitbeam echosounder. Pengukuran dilakukan secara ex-situ pada atau pada watertank. Ikan diikat dengan tali monofilamen, jarak antara permukaan transducer dengan ikan ± 1 m. Hasil dari penelitian ini menunjukkan bahwa nilai target strength rata-rata ikan lele yaitu -55,79 dB dan ikan gabus dengan nilai TS rata-rata yaitu -50,89 dB. Ikan gabus memiliki nilai TS yang lebih besar dikarenakan memiliki ukuran panjang dan bobot yang lebih besar. Ikan gabus juga memiliki organ gelembung renang, sedangkan ikan lele memiliki gelembung renang tetapi tidak berkembang dan memiliki panjang bobot yang lebih kecil.
Control cultural en la gastronomía de San Pedro y San Pablo Teposcolula, Oaxaca, México
Authors: Reyes-Santiago María del Rosario , Pérez-López Elvira Iveth , Méndez-García Elia María del Carmen
Published: June 2024

Objetivo: analizar procesos de cambio en el control cultural de elementos gastronómicos: ingredientes, formas de preparación, conocimiento culinario, consumo y aprovechamiento; en cinco platillos tradicionales de San Pedro y San Pablo Teposcolula, Oaxaca, México. Metodología: la investigación es de corte cualitativo, etnográfico y exploratorio. Se realizó observación participante y entrevistas a cocineras tradicionales. Con la información obtenida se realizó análisis de contenido y triangulación con la literatura revisada. Resultados: el control cultural se presenta como un mosaico de posibilidades que coexisten y satisfacen las necesidades materiales y simbólicas tanto de los miembros de la comunidad como de los visitantes. La diversidad de significados se materializa en diferentes versiones de un mismo platillo. Limitaciones: se necesita mayor investigación e incidencia en los turistas y actores gubernamentales. Conclusiones: evidenciar que no hay una única y homogénea cultura en el ámbito gastronómico comunitario, permite contrarrestar procesos de colonialismo culinario, reconocer los ámbitos en los cuales las cocineras tradicionales conservan el control de los platillos y visibilizar las preparaciones que aun cuando no se ofertan al turismo cumplen una función vital para la comunidad.