bluuebunny/crossref_metadata_2025 huggingface dataset:
Wear Behavior of Ti6Al4V Based Hybrid Composites Reinforced with TiB2(7.5%) + TiC (7.5%)
Authors: Anbarasan P. , Anandajothi M. , Rajamuthamilselvan M.
Published: November 2022

Titanium matrix composites (TMCs) have a greater capacity to realize needs and wishes in aviation, modern firearm systems, and the locomotive sector due to the outstanding specific strength, higher temperature stability, particular stiffness, and resistance to corrosion. However, due to weak tribological characteristics and low hardness, titanium and its alloys' applicability in harsh friction and wear environments are severely constrained. The goal of this research is to improve the wear properties of Ti6Al4V-based hybrid composites reinforced with TiB2(7.5%) + TiC (7.5%). The dry sliding characteristic of powder metallurgy Ti6Al4V alloy and Ti6Al4V/ TiB2(7.5%) + TiC (7.5%) powder metallurgy composites was examined. The wear and friction behaviour of TMCs are explored utilising a pin-on-disk wear tester in a variety of circumstances. The results show that when the sliding speed increases, the particular wear rate increases as well. With the assistance of a Field Emission-Scanning Electron Microscope (FE-SEM) and Energy Dispersive Spectroscopy(EDS), the impact of TiB2 and TiC enhancement on titanium alloy microstructure as well as wear parameters were investigated. The wear resistance of the Ti6Al4V matrix was found to be increased by adding TiB2 and TiC to the sterilised Ti6Al4V matrix.
Numerical Simulation on the Effect of the Cooling Channel Design on the Warpage of a Thin-Wall Injection Molding Product
Authors: Nguyen Tran Phu , Le Thanh Long , Uyen Tran Minh The
Published: November 2022

In this research, the effect of the colling channel design on the warpage of a thin-wall injection molding plastic product has been numerically simulated. Three cooling channel with different designs are considered. The results indicate that the total displacement of warpage on product significantly depends on cooling channel layout. Using a cooling channel with conformal form, the heat accumulation inside the box is released. Therefore, the maximum total displacement dramatically reduces from 1.05 mm in the original design to 0.19 mm. Though increasing conformal cooling channel length will even decrease the maximum displacement to 0.09 mm, the jump of coolant pressure to 86.7 MPa is a big drawback. Therefore, the final suitable design for this system is the short conformal cooling channel.
Microstructure Evolution and Hardness Properties of Nodular Cast Iron for Varying Tempering Time
Authors: Oktadinata Herry , Dafi M. Sa'ban , Prajitno Djoko Hadi
Published: November 2022

Nodular cast iron is usually used for components that require good mechanical properties such as strength, toughness, and ductility. Heat treatment is applied to the components made from the nodular cast iron to improve their mechanical properties. This study aimed to investigate the influence of tempering time on the microstructure, hardness, and wear rate of nodular cast iron. The heat treatment was performed by austenitizing to 850 °C with a holding time of 1 hour and quenched in the oil medium. After quenching, it was tempered at a temperature of 450 °C by varying the tempering time to 15, 30, 45, and 60 min. The investigation consists of microstructure observation, hardness, and wear rate measurements. The results show that the highest hardness was 55.3 HRC at a tempering time of 15 min, and the lowest hardness was 54 HRC at a tempering time of 60 min. The lowest wear rate was 0.00476 g/min at a tempering time of 15 min, and the highest wear rate was 0.00574 g/min at a tempering time of 60 min. It can be concluded that the longer the holding time of tempering, the lower the hardness and the higher the wear rate.
Review of the safety of nonsteroidal anti-inflammatory drugs and selective cyclo-oxygenase-2 inhibitors
Authors: Tarr G. S. , Reuter Helmuth
Published: November 2022

Nonsteroidal anti-inflammatory drugs (NSAIDs) are one of the most common classes of medication used worldwide, and as the ageing population increases, the prevalence of painful arthritic conditions parallels this, resulting in the increased use of NSAIDs. Selective and nonselective cyclo-oxygenase inhibitors should be avoided, or at best used for short periods at the lowest possible effective dose, in patients with underlying artherosclerotic coronary disease.
Is there a difference between an angiotensin-converting enzyme inhibitor and an angiotensin-specific receptor blocker for the treatment of hypertension?
Authors: Ker James A.
Published: November 2022

No abstract available.
Health status of Koraga community: A pilot study among a particularly vulnerable tribal group of Udupi District, Karnataka, India
Authors: Mallya Sneha Deepak , Shreedhar Shyamsundar , Sudhakaran Deepak , Aravindhkumar B. , Nair Suma , Shetty Ranjitha S.
Published: November 2022

Background & objectives:

Undertaking tribe-specific assessment of health status provides the required data for planning appropriate interventions. Hence, a study was conducted to assess the health profile of the Koraga tribe.

Methods:

This community-based cross-sectional study was conducted among a particularly vulnerable tribal group, the Koragas residing in the Udupi district. Data were collected using a pro forma and were analyzed using the SPSS software version 16.0.

Results:

A total of 273 participants aged ≥18 yr and 94 children aged ≤17 yr were recruited through screening and referral services organized in Koraga hamlets of the Udupi district. Among the adults, 59.7 per cent were females and their median age was 35 yr. About 13.9 per cent had elevated blood pressure and 18.4 per cent had impaired/elevated random blood sugar levels. About 47.6 per cent were underweight and 35.2 per cent were anaemic. Multivariate logistic regression analysis showed that individuals with morbidities were more likely to be aged ≥45 yr [45-60 yr: adjusted odds ratio (AOR)=4.3; 95 per cent confidence interval (CI)=1.3-13.8 and >60 yr: AOR=6.4; 95 per cent CI=1.7-23.7] and overweight or obese [23-24.9 kg/m2: AOR=8.1; 95% CI=1.3-48.2 and >25 kg/m2: AOR=7.9; 95% CI=1.6-38.4]. Of the 26 Koraga children aged ≤5 yr, 30.7 and 42.3 per cent had their height for age and weight for age below the third percentile, respectively. Further, 15.3 per cent of under-five children and 27.9 per cent of 6-17 yr old children were severely wasted. About 21.2 per cent of the children aged ≤17 yr were found to be anaemic and 56.3 per cent had symptoms of respiratory tract infection in the past 15 days.

Interpretation & conclusions:

Malnutrition was prevalent among Koraga adults and children, which warrants designing and implementing appropriate social and health interventions in this population.
Non-communicable diseases as a major contributor to deaths in 12 tribal districts in India
Authors: Kaur Prabhdeep , Borah P.K. , Uike Pankaj V. , Mohapatra P.K. , Das Nabajit Kr , Gaigaware Pooja , Tobgay Karma Jigme , Tushi Aonungdok , Zorinsangi  , Mazumdar Gautam , Marak Bibha , Pizi Dirang , Chakma Tapas , Sugunan A.P. , Vijayachari P. , Bhardwaj Rakesh R. , Arambam Probin C. , Kutum Tridip , Sharma Anand , Pal Piyalee , Shanmugapriya P.C. , Manivel Prathab , Kaliyamoorthy Neelakandan , Chakma Joy , Mathur Prashant , Dhaliwal R.S. , Mahanta J. , Mehendale Sanjay M.
Published: November 2022

Background & objectives:

Non-communicable diseases (NCDs) are the leading cause of death in India. Although studies have reported a high prevalence of NCD in tribal populations, there are limited data pertaining mortality due to NCDs. Therefore, in this study we estimated the proportion of deaths due to NCDs among 15 yr and older age group in tribal districts in India.

Methods:

We conducted a community-based survey in 12 districts (one per State) with more than 50 per cent tribal population. Data were collected using a verbal autopsy tool from the family member of the deceased. The estimated sample size was 452 deaths per district. We obtained the list of deaths for the reference period of one year and updated it during the survey. The cause of death was assigned using the International Classification of Diseases-10 classification and analyzed the proportions of causes of death. The age-standardized death rate (ASRD) was also estimated.

Results:

We surveyed 5292 deaths among those above 15 years of age. Overall, NCDs accounted for 66 per cent of the deaths, followed by infectious diseases (15%) and injuries (11%). Cardiovascular diseases were the leading cause of death in 10 of the 12 sites. In East Garo Hills (18%) and Lunglei (26%), neoplasms were the leading cause of death. ASRD due to NCD ranged from 426 in Kinnaur to 756 per 100,000 in East Garo Hills.

Interpretation & conclusions:

The findings of this community-based survey suggested that NCDs were the leading cause of death among the tribal populations in India. It is hence suggested that control of NCDs should be one of the public health priorities for tribal districts in India.
Molecular Detection of Neglected Tropical Diseases: The Case for Automated Near–Point-of-Care Diagnosis of Leishmaniasis
Authors: Gow Ineka , Smith Nicholas , Stark Damien , Ellis John
Published: November 2022

Neglected tropical diseases affect those in poorer nations disproportionately across the globe. One example of these, leishmaniasis, is a debilitating and potentially fatal parasitic infection. Molecular detection of this disease can provide accurate and fast diagnosis, and with near point-of-care technologies, detection can be provided in many health-care settings. Traditionally, the perceived limitations to such detection methods have hindered their provision to resource-limited nations, but new technologies and techniques are helping to overcome these perceptions. The current pandemic offers an opportunity to maintain and develop further advances, ensuring molecular diagnostics are accessible to all.
Down to the root of vegetated soil: challenges and state-of-the-art
Authors: Cheng Hongyang , Anselmucci Floriana A. R. , Fan Xinyan , Zeng Yijian , Luding Stefan , Magnanimo Vanessa
Published: November 2022

Vegetated soil plays an essential role in confronting climate change. It is the host material where inorganic carbon is stored and green infrastructures are built. The expected impacts of climate change, such as extreme wetting-drying cycles, pose an urgent need to understand the interplay between soil deformation, root growth, and water/solute uptake. The key to this challenge lies in the extension of unsaturated soil mechanics to incorporate bio-hydrological processes, such as root growth and water uptake. In this paper, we first provide an overview of the state-of-the-art knowledge of root-zone mechanics and bio-hydrology. We identify the main knowledge gaps and suggest an integrated, bottom-to-top approach to develop a multidisciplinary understanding of soil-water-root interaction. We demonstrate how emerging experimental and numerical methods can be used to study rooted soil under wetting--drying cycles. Although focused on the biophysical processes at root/soil particle scales, we discuss potential up-scaling from the root to the field scale and further research on remaining challenges, such as the microbial activities in vegetated soil.
Assessment of thyroid dysfunction in type 2 diabetes mellitus patients in Sokoto, North -Western Nigeria
Authors: AbdulRahman M.B. , Jamilu L. , Ladan M.J. , Sahabi D.M. , Abdullahi U.A. , Aminu B. , Fakku A.A. , Kasimu S. , Adanlawo W.T. , Birnin Kebbi M.M. , Sanusi K.O.
Published: November 2022

Diabetes Mellitus (DM) and Thyroid Dysfunction (TD) are the two most common endocrinopathies seen in general population. Type 2 diabetes mellitus (T2DM) is commonly associated with altered thyroid function. The aim of this study is to evaluate TD in patients with T2DM in Sokoto, Nigeria. Blood samples were collected from 80 type 2 diabetic patients and equal number of apparently healthy matched controls and analyzed for fasting blood sugar (FBS), glycated hemoglobin (HbA1c), thyroid stimulating hormone (TSH), triiodothyronine (T3), thyroxine (T4), cholesterol, triglycerides (TG), high density lipoprotein (HDL-C), and low density lipoprotein (LDL-C). The mean age of T2DM patients and controls were 37.06±6.09 and 37.10±9.90 respetively. The levels of FBS, HbA1c, Cholesterol, TG, and LDL-C were observed to be significantly high and the level of HDL-C was significantly low in diabetics as compared to control. The levels of T3 and T4 were significantly low while the level of TSH was significantly high in Type 2 diabetics. Thyroid dysfunction may complicate metabolic control in diabetes mellitus. It’s important for routine screening of thyroid disease (hormones) among patients with diabetes so as to stabilize metabolic control and reduce morbidity.
Drug utilization pattern among paediatric asthma patients attending the respiratory clinic of a Nigerian tertiary hospital: a five-year retrospective survey
Authors: Amorha K. C. , Isiogugu O. N. , Nsionu E. C.
Published: November 2022

Drug prescribing indicators can assess prescribing performance. This study assessed the drug utilization pattern among paediatric asthma patients in University of Nigeria Teaching Hospital (UNTH). The study protocol for this five-year retrospective survey (1st January, 2015 to 31st December, 2019) was approved by the Health Research and Ethics Committee of UNTH. Eligibility criteria included folders of the paediatric asthma patients within the period under review. Descriptive statistics summarized the data and World Health Organization (WHO)/International Network of Rational Use of Drugs (INRUD) core prescribing indicators.

The result presented that 272 prescriptions were extracted from the 68 folders. Majority of the patients were ≤ 10 years old (n = 167, 61.4%) and allergic rhinitis (n = 62, 22.8%) was the most common comorbidity. Antihistamines (n = 1407, 35.5%) were the most commonly prescribed class of drugs. Salbutamol (n = 156, 100.0%) was the only prescribed short-acting beta agonist (SABA) inhaler. The average number of drugs per encounter was 2.92 (reference range: 1.6 – 1.8). The percentage of drugs prescribed by generic name and from the essential drugs list were 66.2% and 18.1%, respectively (expected compliance: 100%). The percentage of encounters with inclusion of prescription of an antibiotic was 22.1% (reference range: 20.0% – 26.8%). The percentage of encounters with inclusion of prescription of an injection was 9.6% (reference range: 13.4% – 24.1%).

Our conclusion was that there is need for rational prescribing in asthma settings, with focus on prescribing drugs using their generic name and also from the essential drugs list, while avoiding unnecessary polypharmacy.
Biochemical effects of lambdacyhalothrin on activities of some detoxifying enzymes of Anopheles gambiae life cycle stages
Authors: Okoh F. N.
Published: November 2022

Recent decrease in global malaria burden was achieved through vector control interventions with pyrethroid insecticides. This study was carried out to determine the influence of lambdacyhalothrin on the physiology and activities of some detoxifying enzymes and to establish the systemic effects on Anopheles gambiae. The life cycle stages of the vector were exposed to six different concentrations of lambdacyhalothrin, in an insectary. After the toxicity tests, 325 each, of the dead eggs, larvae and pupae, and 175 of the dead adults from the toxicity test, were carefully selected and further used for enzyme study. Fifty (50) individuals were used for experimental study and 25 as control, for each of egg, larvae and pupae; 25 were used for experimental study and 25 as control for the adult. Each sample was homogenized in 10ml 0.1M phosphate buffer of pH 7.4, filtered and the filtrate used for enzymes study. Determination of the enzymes: aspartate aminotransferase (AST), alanine aminotransferase (ALT) and alkaline phosphatase (ALP) was done using standard biochemical methods. The results showed that 97% mortality of the life cycle stages was achieved following exposure to six concentrations of lambdacyhalothrin. Some concentrations (1 and 05µg/l) induced stimulatory effect on the enzyme activities while others (15 and 25µg/l) elicited inhibitory effect and some (10µg/l and 20µg/l) had no significant effect (p>0.05) on the enzyme activities. Alkaline phosphatase (ALP) was the most active in all the life cycle stages. Nevertheless, in older stages (pupae and adults), AST and ALT activities were significantly (p<0.05) elevated. This suggests that lambdacyhalothrin is promising in providing effective mosquito control. The results also suggest that the enzymes play a part in detoxification of lambdacyhalothrin and hence could be correlated with the pyrethroid tolerance status of A. gambiae.
Effects of Wetland Policy on Conservation and Household Incomes in Kabale District, Uganda
Authors: Masanyu Julius , Oonyu Joseph
Published: November 2022

This study aimed at establishing why wetland degradation persists in Uganda despite Ramsar and other wetland policy interventions. The objectives were to assess local peoples’ attitudes towards wetlands; assess the level of illegal activities in wetlands; and assess the contribution of wetland management programs and projects to household incomes. We used a cross-sectional mixed methods design and targeted 120 respondents, including residents and opinion leaders in KabaleDistrict. The study showed that fifty three percent of the respondents perceived wetlands favourably. Fifty seven percent of the respondents reported illegal activities of burning followed by hunting at 20%. Twenty two percent did not get any monetary income from wetlands while 43 percent reported getting between shillings 10,000-100,000 annually. Only 12 percent reported getting above 1 million shillings. Illegal activities persisted because of land shortage and being desperate due to lack of other alternatives. In Kabale District, only Nyamuriro wetland project, covering Ikumba and Muko sub counties, implemented wetland restoration. We concluded that the wetland policy has had little impact on household incomes and illegal activities in wetlands. We recommended continuous sensitisation.
High-order Polynomial Comparison and Masking Lattice-based Encryption
Authors: Coron Jean-Sébastien , Gérard François , Montoya Simon , Zeitoun Rina
Published: November 2022

The main protection against side-channel attacks consists in computing every function with multiple shares via the masking countermeasure. For IND-CCA secure lattice-based encryption schemes, the masking of the decryption algorithm requires the high-order computation of a polynomial comparison. In this paper, we describe and evaluate a number of different techniques for such high-order comparison, always with a security proof in the ISW probing model. As an application, we describe the full high-order masking of the NIST standard Kyber, with a concrete implementation on ARM Cortex M architecture, and a t-test evaluation.
World Professional Skills Competitions as a Way of Professional Education Internationalization
Authors: Khan S. I. , Kharina I. V.
Published: November 2022

This article deals with the development of secondary vocational education and training (SVET) in the context of globalization processes. International cooperation is one of the priorities in the development of the SVET system. Constant updating of the educational content and technologies is necessitated by the professional qualiﬁcation requirements and international standards. A promising area of professional education internationalization could be arrangement of international competitions and professional skills championships in the WorldSkills format. Far East State Transport University (FESTU) took part in organizing the WorldSkills BRICS Championship in the “Rail transport technologies” competence in 2022 and it is described in this paper. The professional skills competitions enhance the development of professional and expert communities, professional development of scientists, engineers, and workers in Russia and globally. Such competitions can become one of the main forms of vocational education internationalization, which will enhance and improve education quality overall.
Efficacy of Cognitive Behavioural Therapy for Patients with Chronic Pain in Singapore
Authors: Tan Esther PG , Tan Evangeline SL , Ng Beng-Yeong
Published: November 2022

Background: The use of Cognitive Behavioural Therapy (CBT) techniques to manage chronic pain is relatively new and understudied in Singapore. Using data collected from group CBT programmes carried out at the Singapore General Hospital (SGH), we seek to explore the ef- ficacy of the programme on pain intensity, self-efficacy, attitudes towards pain, and emotional factors. We also examined the efficacy of the longer 6- to 9-day group programme versus an abridged 2-day version called the Pacing Programme covering only some aspects of the full group programme.

Materials and Methods: Twenty-nine adult patients underwent the intensive 6- to 9-day group programme while another 10 patients underwent the abridged 2-day group programme. The more extensive group programme encompassed teaching patients cognitive- behavioural methods of coping with pain, such as setting goals, pacing, cognitive restructuring by thinking in more positively, distraction, problem solving, sleep hygiene, communication skills, ability to cope with changes, and relaxation techniques. The abridged programme focused mainly on developing pacing skills. Patients were required to fill out questionnaires at the begin- ning of the programme, end of the programme, and at the 1-month and 6-month follow-ups to monitor progress.

Results: Preliminary results for the intensive 6- to 9-day group programme indicate decrease in pain and pain distress levels, improvements in management of pain, in- creased confidence to carry out activities despite pain, increased positive self-statements and decreased negative self-statements, decrease in fear of harm and pathophysiological beliefs, as well as decreases in the levels of depression, anxiety, and stress. The abridged 2-day programme yielded little change in pain and pain distress levels, but a slight increase in confidence to carry out activities despite pain.

Conclusion: These preliminary results provide some evidence supporting the efficacy of CBT techniques in chronic pain management and contribute to the growing body of evidence for the effectiveness of psychological and behavioural techniques in the management of chronic pain.

Key words: Group, Multi-disciplinary treatment, Psychological intervention, Psychotherapy
Clinical Aspects and Management of Fibromyalgia Syndrome
Authors: Chong Yong-Yeow , Ng Beng-Yeong
Published: November 2022

Fibromyalgia syndrome (FMS) is a chronic and debilitating musculoskeletal pain disorder of unknown aetiology with usual accompanying features of fatigue, sleep disturbances and stiff- ness. Its place in medical textbooks was controversial with rheumatologists holding the helm of its management for many years. Over the last decade, abnormalities have been identified at multiple levels in the peripheral, central, and sympathetic nervous systems as well as the hypothalomo-pitutary-adrenal axis stress response system. With the elucidation of these pathways of pain, FMS is known more as a central sensitivity syndrome. This led to tremendous increment in interest in both pharmacological and non-pharmacological treatment of FMS. The United States Food and Drug Administration (FDA) has also successively approved 3 drugs for the management of fibromyalgia – pregabalin, duloxetine and milnacipran. Non-pharmacological modalities showed aerobic exercise, patient education and cognitive behavioural therapy to be most effective. Overall, management of FMS requires a multi-disciplinary approach.

Key words: Aetiology, Fibromyalgia-Fibromyositis Syndromes, History, Pain syndrome
A Cross-Sectional Study on Reference Ranges of Normal Oral Temperatures Among Students in Singapore
Authors: Liew Pei Xiong , Ge Feng , Gullo Charles , Teoh Gerrard KH , William YK William YK
Published: November 2022

Introduction: During the 2003 Severe Acute Respiratory Syndrome (SARS) outbreak, all schools in Singapore implemented twice-daily temperature monitoring for students to curtail the spread of the disease. Students were not allowed to attend school if their temperature readings were >37.8oC for students ≤12 years old, or ≥37.5oC for students >12 years old. These values had been arbitrarily determined with professional inputs. The aim of this study is to determine the reference ranges of normal oral temperatures of students in Singapore and recommend the cut-off values for febrile patients. This may be used in another similar outbreak of an infectious disease with fever. Materials and Methods: Four co-ed primary schools and 4 co-ed secondary schools were selected for this study. Four thousand and two hundred primary 1 to secondary 3 students responded (96.8%) and participated in this cross-sectional study. The mean ages of the students in the lowest (primary 1) and highest educational levels (secondary 3) were 7.4 years old and 15.3 years old, respectively. Twelve oral temperature readings per student (i.e. measurements taken 4 times a day in 3 consecutive days) were collected. Forty-six thousand seven hundred and eighty-three (92.8%) out of 50,400 temperature readings were used for the analysis as missing data were excluded. A quantile regression model was applied to estimate reference ranges of normal oral temperatures for students with adjustment for potential confounding factors. Results: The age-specific reference ranges of normal oral temperature from this study for students ≤12 years old and >12 years old were 35.7oC to 37.7oC and 35.6oC to 37.4oC, respectively. Temperatures of 37.8oC and 37.5oC are therefore recommended as the oral temperature cut-offs for those ≤12 years old and >12 years old, respectively. Conclusion: This study has provided empirical data on normal oral temperature cut-offs which could be used during temperature screening in schools. Key words: Cut-offs, Infectious diseases, SARS
Association Between Rectosigmoid Adenomas and Cardiovascular Risk Factors: A Hospital-based, Cross-sectional Study
Authors: Liao Kuan-Fu , Lai Hsueh-Chou , Lai Shih-Wei , Cheng Kao-Chi , Lin Chih-Hsueh
Published: November 2022

Introduction: Little was known about the association between colorectal adenomas and cardiovascular risk factors in Taiwan. The aim of this study was to assess the association between rectosigmoid adenomas and related factors.

Materials and Methods: This was a hospital-based, cross-sectional study. We analysed subjects receiving self-referred health examinations at 1 medical centre in Taiwan between 2001 and 2004. In total, 4413 subjects were enrolled in this study. There were 2444 men (55.4%) and 1969 women (44.6%). The mean age was 49.3 ±12.3 years (range, 20 to 87). All subjects underwent a 60-cm flexible sigmoidoscopic examination and laboratory survey. Adjusted odds ratio (OR) and 95% confidence interval (CI) were expressed using a multivariate logistic regression analysis.

Results: In the final model, increasing age (OR, 1.05; 95% CI, 1.03-1.06), hypertriglyceridemia (OR, 1.49; 95% CI, 1.07-2.07), and alcohol consumption (OR, 2.11; 95% CI, 1.47-3.04) were the risk factors for rectosigmoid adenomas in men. Increasing age was the only risk factor for rectosigmoid adenomas in women (OR, 1.03; 95% CI, 1.01-1.06).

Conclusion: Age, hypertriglyceridemia and alcohol consumption are associated with rectosigmoid adenomas in men, and only age is significantly associated with rectosigmoid adenomas in women.

Key words: Alcohol, Cardiovascular, Hypertriglyceridemia
The MERCI Retrieval System for the Management of Acute Ischaemic Stroke – The NNI Singapore Experience
Authors: Lee Wickly , Sitoh Yih-Yian , Lim CC Tchoyoson , Lim Winston EH , Hui Francis KH
Published: November 2022

Introduction: Systemic and local intra-arterial thrombolysis in patients with large vessel ischaemic stroke is hampered by poor re-canalisation rates and risk of haemorrhage. The Merci Retrieval System is an endovascular device for removal of acute intracranial thrombus. We present our initial experience using this device in conjunction with existing thrombolytic therapy already in place in our institute.

Materials and Methods: Prospective data in all patients presenting with large vessel ischaemic stroke treated using the Merci Retrieval System from July 2007 to March 2009 were analysed. Selection criteria for patients were similar to the multi- Merci trial of 2008. We compared re-canalisation rate, National Institutes of Health Stroke Score (NIHSS) and modified Rankin score (mRS) outcomes to the published trial results.

Results: Seventeen patients were reviewed; none suffered immediate post-procedural complications. Fifteen underwent successful thrombus retrieval but in 2 cases the device failed due to technical considerations. Sites of vascular occlusion included: ICA/ICA-‘T’ junctions 27%, middle cerebral artery 13% and vertebrobasilar artery 60%. Of the 15 patients treated by MERCI with or without adjuvant thrombolytic therapy, complete re-canalisation was achieved in 60%, partial re-canalisation in 20%, partial re-canalisation with persistent distal vessel occlusion in 6% and failure of re-canalisation in 14%. Asymptomatic haemorrhage occurred in 33% and there was 1 death (6%) from symptomatic haemorrhage. Pre-treatment median NIHSS was
17.88 and 9.5 immediately post-treatment. Median mRS at 30 days was 2.6 for patients who achieved complete re-canalisation and 4.5 in failure or partial re-canalisation with or without persistent distal vessel occlusion.

Conclusion: Re-canalisation rates using the Merci Retrieval System was comparable to the multi-Merci trial. Haemorrhagic complications and safety were also found to be satisfactory. Importantly, treatment success with eventual good clinical outcome hinges strongly on the ability of the device to achieve complete re-canalisation.

Key words: Acute ischaemic stroke, Mechanical revascularisation, Thrombectomy, The Merci Retrieval System
HAVE WE MISCONSTRUED CHRIST’S PRIESTLY AND KINGLY WORK? A Discussion on Analytic and Exegetical Christology
Authors: Oswan Devina Benlin
Published: November 2022

Within the framework of traditional Christology, the most common interpretation of Christ’s three-fold office is that Christ’s work as our High Priest culminated on the cross as He suffered divine wrath and judgment, while His kingly rule began at His resurrection and ascension. However, with respect to the priestly role, David Moffitt challenges this common understanding and argues that, based on a careful reading of the Epistle to the Hebrews, Christ’s atoning sacrifice ultimately took place during His ascension. Complementing Moffitt’s account, I argue that Christ’s kingly work climaxed in His death on the cross. Using the tools of analytic method, I shall analyze 2 Chronicles 33:1-20 and offer an interpretation to support my argument. If Moffitt’s and my account is Scripturally tenable, it is safe to conclude that traditional Christology has mistakenly reversed Christ’s priestly and kingly role.
Determinants of costumer’s to use Islamic bank: The case of muhammadiyah in region Yogyakarta
Authors: Wahyudi Rofiul , Almira Almira Rosa Bella
Published: November 2022

This study examines the effect of personal, product, social, and promotion factors on Muhammadiyah residents using Islamic banking at the BSI Yogyakarta Branch. This research uses quantitative research methods with associative research types. The data sources used were primary and secondary data sources. Primary data were obtained through a questionnaire (questionnaire) distributed to Muhammadiyah residents, while secondary data sources were obtained through references. The results showed that Personal Factors, Social Factors, Product Factors, and Promotional Factors partially and simultaneously had a positive and significant effect on the decision of Muhammadiyah residents to use Islamic banks.
ManiacNFT : An Application for NFT Marketplace
Authors: Laud Gaurav , Aishwarya Pardhi  , Ajinkya Wadekar  , Shounik Shukla  , Varad Loya  , Dr. Padma Adane  , Viresh Dhawan
Published: November 2022

Art is mankind's treasure, yet it is often concentrated in the hands of a few. We need a better trade mechanism and technological innovation to enable fair access to artworks. A solution to the problem can be found by using the NFT technology for the trade of artwork. NFTs make the future for the creators’ economy a little brighter, allowing artists to monetize their work by selling to eager collectors, while also collecting due royalties upon future resales of their works. This unique combination of blockchain with artworks provides a layer of security to the ownership of the artwork, and is restoring access to artworks for people from all regions.This research paper is about a decentralized marketplace application where one can buy and sell artworks in the form of NFTs digitally, providing the users with the facility to securely perform transactions of these NFTs that can be verified through Polygon blockchain.
Design and Analysis of Multipliers for DNN application using approximate 4:2 Compressors
Authors: Anjankar Shubham , Hemant Gillurkar  , Joshi Pankaj , Dwaramwar Pravin
Published: November 2022

The demand for Deep Learning applications in resource constrained devices is booming in recent years. Theuse of Deep Neural Network (DNN) is the leading method in these applications which has error resilient nature.This allows the use of Approximate Computing for efficient computation to leverage efficiency accuracy tradeoff by replacing Approximate Multiplier in place of exact multipliers. In this paper we proposed ApproximateCompressors and compared them in different cases of 8 bit integer dadda multipliers in terms of the Error metricsand accuracy in real life object classification applications. The approximate multipliers are designed using differentcompressors and used to perform multiplication in ResNet. We have proposed two approximate compressorsdesigns Design 1 and Design 2.The proposed 4:2 compressors design shows the more correct outputs and lessWorst Case Relative Error (WCRE) in the range of 2-16. Our proposed 4:2 compressor Design1 is utilized in themodified Reduction circuitry of dadda multiplier and shows the accuracy of 81.6 % for DNN application
Role of Blockchain Technology and Machine Learning in Design of Smart and Secure Warehouse Management System: A Survey
Authors: HANDE KAPIL , Dr Manoj B Chandak
Published: November 2022

Blockchain network is defined as interconnection of many computers, and each and every computer holds the copy of the ledger. It can be observed as continuously budding chain of blocks, and blocks are interconnected with the support of hash function. Validating of new blocks is followed by a set of protocols and consensus mechanism from every node in the network. The records are kept and arranged in linear fashion chain. The main feature of the Blockchain technology is that it allows secure communication between untrusted parties without the involvement of any third party authority. Artificial intelligence, which emulates the human intelligence, is impacting heavily on the business and social media applications nowadays. Machine learning which is the subset AI, automatically learns and improve based on input data. Whereas deep learning which is subset of machine learning uses networks to identify complex patterns in data. The basic approach of machine learning is to collect and analyze the data at central location like server. But in today’s scenario the data is decentralized and emerges from multiple sources. Hence the need of distributed machine learning algorithms in many applications is required. ML can be used to make chain smarter than before. By making use of decentralized data architecture of Blockchain we can build good models of machine learning. This paper investigates the possibility of integrating Blockchain Technology and Machine learning for optimization and improvement of Warehouse operations at data and transactions levels by providing security processes needed for smart and secure warehouse system.
Experimental Study on Overall Cooling Effectiveness of Turbine Nozzle Guide Vane with Impingement-Cutback Structure
Authors: He H. B. , Duan F. F. , Li G. C.
Published: November 2022

The overall cooling performance of turbine nozzle guide vane, with the impingement-cutback structure, is experimentally studied in the actual-scale cascade. The gas with the high temperature is used to achieve the actual dynamic viscosity coefficient and the density ratios. The coolant-to-gas mass flow ratio (KG) varies between 0.034 and 0.050 and the gas-to-coolant temperature ratio (KT) varies between 1.5 and 2.4. The local Overall Cooling Effectiveness (OCE) on the middle cross-section of the vane is obtained. The experimental results reveal that the lowest value of the OCE achieves a 10% relative arc length on the suction side of the vane; however, the highest value appears at 40% relative arc length on the pressure side of the vane. The averaged values of the OCE are respectively enhanced by 19.45%, 24.22%, and 35.57% at temperature ratios equal to 1.7, 1.9, and 2.3, with an increase of the KG from 0.034 to 0.050. Added to that, it was identified that an increase of KT from 1.7 to 2.3 leads to the decrease of the OCE. The comparison results show that this characteristic becomes dramatical while KG is 0.034. The higher KT leads to a greater influence of KG, which is illustrated clearly by the compared results of the OCE.
Effect of Lobe Count and Lobe Length of Corrugated Lobed Nozzle on Subsonic Flow Characteristics
Authors: Roy V. P. , Kriparaj K. G. , Tide P. S. , Biju N.
Published: November 2022

The corrugated lobed nozzle is an emerging research topic in jet flow dynamics, and little investigation has been conducted on its effect on flow characteristics. Thus, in this study, the effects of lobe count and lobe length of corrugated lobed nozzles on subsonic jet characteristics were experimentally investigated by analyzing the velocity profiles of the jets emanating from the nozzles. The Pitot tube readings were obtained by varying the count (4 ≤ N ≤ 8) and length (10 mm ≤ L ≤ 20 mm) of corrugated lobes. These measurements were then compared with the experimental readings obtained for a baseline circular nozzle. The nozzle pressure ratio (NPR) and exit nozzle area were kept identical at 1.5 and 600 mm2, respectively, for all nozzle configurations. The most striking observation was the ‘W’-shaped radial velocity profile of the corrugated nozzle, which differed from the ‘Top hat’ profile of the baseline circular nozzle. Additionally, the length of the potential central region of the corrugated nozzle was always shorter than that of the baseline circular nozzle, indicating the early occurrence of turbulence in the former. It was found that the lobe length had a meagre effect on the velocity variation in the jet issuing from the corrugated nozzle, whereas the lobe count had a significant effect on the velocity profile. However, as the lobe count increased, the velocity profile of the corrugated nozzle gradually resembled that of the circular nozzle. The findings of this study would be beneficial for selecting a proper lobe count and lobe length while designing and implementing a corrugated lobed nozzle.
Effect of Inclination Grooves on Axial Flow Compressor Stability: An Experimental and Numerical Simulation Study
Authors: Liu H. W. , Chu W. L. , Zhang H. G. , Zhang C. Y.
Published: November 2022

In the present study, various groove casing treatments were evaluated under a high-speed subsonic axial flow compressor using experimental and numerical simulation methods. The aim of this study was to explore the effect of inclination of grooves on compressor stability and performance. The potential flow mechanisms were also evaluated. Three different inclination grooves were designed in this study: grooves with no inclination, grooves with 30 degrees upstream inclination and grooves with 30 degrees downstream inclination. Similar effect of the grooves on the compressor stability and efficiency was observed under experimental and numerical analyses. The grooves with no inclination, 30 degrees upstream inclination and 30 degrees downstream inclination enhanced stall margin by 6.08%, 8.74% and 3.03%, respectively. The peak efficiency losses of the three types of grooves were 1.62%, 0.94% and 2.33%, respectively. Tip flow field analyses demonstrated that the radial transport effect caused by grooves effectively reduced tip loads and alleviated tip blockage. This explains why the grooves enhanced the compressor stability. The radial transport effect was enhanced, and a larger stall margin improvement was obtained when grooves inclined upstream were applied. The tip flow loss was the dominant loss observed after grooves were applied on the compressor. The grooves with upstream inclination markedly reduced the tip flow loss, indicating that they exhibited the lowest effect on reducing compressor efficiency compared with the other types of grooves.
Shape Optimization of an Asymmetric Airfoil for Low Wind Speed Region having Adjoint-Based Optimization Technique
Authors: Shinde P. , Ohol S. S. , Tripathi V. K.
Published: November 2022

The land needed to install wind turbines is shrinking as power generation from renewable energy sources increases significantly. A large number of studies are being conducted to maximize the power extraction from wind turbines in areas with low wind speeds. Wind turbine blades play a significant role in utilizing the maximum amount of energy from the wind. The aerodynamic performance of a wind turbine blade depends on the airfoil shape. The shape optimization of an asymmetric S2027 airfoil for a low wind speed region was investigated using the adjoint-based optimization technique. The primary objectives of this study were to maximize the lift coefficient, minimize the drag coefficient, and maximize the lift-to-drag ratio. The optimization is based on the adjoint method for Reynolds number variation in the range of 2 × 105 to 5 × 105 and an angle of attack variation from 0° to 12°. A two-dimensional Reynolds–Averaged Navier–Strokes Computational Fluid Dynamics model was created with all the operating parameters and used for optimization. The aerodynamic performance was validated experimentally. For each optimization function, approximately 16 shapes were obtained. The aerodynamic performance for each optimized shape was determined under different operating conditions. Different airfoil shapes with a specific chord, leading and trailing edges, and span arrangement was obtained. The drag coefficient was reduced by 2%–30%; the lift coefficient was improved by 2%–35%, and the lift-to-drag ratio was improved up to 40%.
Penapisan Virtual Senyawa Aktif Sirih Merah (Piper crocatum) sebagai Inhibitor Angiotensin Converting Enzyme
Authors:   Institut Pertanian Bogor, Putera Irsal Riyan Alifbi , Hami Seno Djarot Sasongko ,   Institut Pertanian Bogor, Safithri Mega ,   Institut Pertanian Bogor, Kurniasih Rini ,   Institut Pertanian Bogor
Published: November 2022

Lisinopril (Angiotensin Converting Enzyme inhibitor) merupakan obat pilihan lini pertama dalam pengobatan hipertensi, namun obat tersebut masih memiliki banyak efek samping. Sirih merah telah banyak digunakan dalam pengobatan herbal dan diharapkan berpotensi menghambat aktivitas ACE (Angiotensin Converting Enzyme). Penelitian ini bertujuan untuk menemukan senyawa aktif yang berpotensi menghambat ACE in silico dengan metode molecular anchoring. Enzim ACE memiliki sisi pengikatan Metal binding yang mengikat di logam zinc, interaksi tersebut melibatkan asam amino HIS383, HIS387, dan GLU411. Situs aktif dari enzim ACE terletak pada asam amino GLU384. Ion zinc merupakan komponen penting dari ACE karena terikat pada situs aktif. Terdapat 7 ligan yang berinteraksi dengan asam amino penting sesuai ligan alami dan bernilai (bebas Gibbs dan Ki) lebih negatif dari ligan alaminya. Terdapat 1 ligan yang menjadi terbaik diantara 7 ligan yaitu, 3S,5R,8R,9R,10R,12R,13R,14R,17S)-17-[(2S)-5-[2-(3,4-dimethoxyphenyl)ethylamino]-2-hydroxypentan-2-yl]- 4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,12- diol.
Consistency of Resistance and Nature in Mahmoud Darwish’s Poetry in Exile: Critical Reading in Selected Poems
Authors: Al-Sakkaf Ahmed Abdullah Ahmed , Tayeb Yahya Ameen
Published: November 2022

The aim of this paper is to explore Mahmoud Darwish’s consistency of resistance and nature to the aggression of homeland occupation of Palestine as depicted in selected poems during his exile. In spite of Darwish exile from Palestine, the sense of resistance and opposition can be elicited from his poetic voice momentum regardless of the wide distance between him and his own homeland. In this research paper, the discussion will mainly focus on how Darwish metaphorically develops Palestinian nature creating a unique world full with righteous and justifiable opposition to the hatred colonizers of his homeland in his selected poems of exile. Theoretically, the framework of this study mainly relied on the postcolonial and the ecocritical theories of reading literature which is defined as an ecoresistance framework. Critically, the implications beyond the various notions of ecoresistance in the exile selected poems by an intellectual giant as Mahmoud Darwish, the researchers expect to provide new insights into man’s interrelation with land as an approach to resist the aggression of colonialism.
Tahap Pengetahuan dan Persepsi Guru Terhadap Pengaplikasian TMK dalam Pengajaran Matematik Sekolah Rendah
Authors: Poobalan Mercy Cynthia , Mahmud Muhammad Sofwan
Published: November 2022

Teknologi Maklumat dan Komunikasi (TMK) mengalami perubahan yang ketara sejak beberapa dekad yang lepas. Perubahan ini turut mempengaruhi pengaplikasiannya dalam sistem pendidikan di seluruh dunia. Pelbagai kaedah pengajaran dan strategi pengajaran yang dikaitkan dengan TMK ini turut diperkenalkan dalam pengajaran dan pembelajaran matematik. Pengaplikasian TMK dalam pengajaran Matematik membawa pelbagai faedah kepada murid. Guru matematik yang memahami kepentingan pengaplikasian TMK ini akan menggunakan TMK dalam pengajaran mereka. Persepsi dan pengetahuan seorang guru mengenai TMK juga akan memberi impak dalam pengaplikasian TMK dalam pengajaran mereka. Pandangan pengkaji lepas mengenai aspek demografi seperti jantina dan pengalaman mengajar turut diambil kira dan dibincangkan dalam artikel ini.