bluuebunny/crossref_metadata_2025 huggingface dataset:
Sine-wave pattern in a case of severe hyperkalemia and end-stage renal failure from a hospital in a rural area: A case report and narrative review
Authors: Sebastian Matthew , Erbano Briandy Rangga Hernawang , Wardhana Yos Kresno
Published: September 2024

Background: A sine-wave pattern in electrocardiography (ECG) is one of the manifestations of severe hyperkalemia and requires rapid medical intervention and urgent hemodialysis. This manifestation has high specificity for detecting hyperkalemia, and rapid medical intervention is required upon first medical contact.
Case Description: A 60-year-old woman presents to the emergency room with generalized weakness that started around two days ago, and became increasingly more severe and noticeable to the point that the patient went to the emergency department. The patient initially was stable and experienced no other complaints including chest pain or dyspnea. A 12-lead ECG was obtained which showed the sine-wave morphology. Minutes later, the patient rapidly deteriorated and underwent cardiac arrest while waiting for lab results to confirm the hyperkalemia. The patient was resuscitated successfully and lab results confirmed potassium levels of 9.7mmol/L and a creatinine level of 9.55mg/dL (estimated GFR using CKD-EPI formula of 4 ml/min/1.73m2. The patient underwent potassium correction therapy with fast-acting insulin agents, dextrose and calcium gluconate infusions. A secondary ECG post ROSC and potassium correction therapy was taken, showing a reversal of the sine-wave pattern into an accelerated junctional rhythm with tall T waves. Chest X-ray was performed and showed cardiomegaly, and the patient was admitted into the ICU to undergo urgent hemodialysis.
Conclusion: This case further emphasizes the importance of recognizing ECG manifestations of hyperkalemia and rapid management after recognition of said ECG patterns to prevent the clinical deterioration of the patient and potentially fatal outcomes should be undertaken as soon as possible.
Survival and reverse progression outcome of fetal aortic valvuloplasty and extra-cardiac conduit or lateral tunnel Fontan procedure in evolving and evolved hypoplastic left heart syndrome: a systematic review and meta-analysis
Authors: Dewi Cokorda Istri Dyah Yustika , Winata I Gde Sastra , Pertiwi Putu Febry Krisna , Jagannatha Gusti Ngurah Prana
Published: September 2024

Background: Hypoplastic left heart syndrome (HLHS) is a severe congenital heart defect characterized by the underdevelopment of the left-sided heart structures, necessitating staged univentricular palliation to repurpose the right ventricle as the systemic pumping chamber. While the Fontan procedure offers a well-established method to manage single-ventricle physiology and improve survival, the potential of fetal aortic valvuloplasty (FAV) to prevent the progression of critical aortic stenosis to HLHS and achieve biventricular circulation postnatally remains significant. However, the long-term outcomes of both interventions are still uncertain. Therefore this study aims to evaluate the survival and reverse progression outcome of fetal aortic valvuloplasty and extra-cardiac conduit or lateral tunnel Fontan procedure in evolving and evolved hypoplastic left heart syndrome
Methods: The literature search was conducted using PubMed, ScienceDirect, and Google Scholar databases up to May 2024. The analyses in this study were performed using R statistical software v.3.3.
Results: This analysis reviewed 25 prospective and retrospective cohort studies discussing the outcomes of the FAV procedure in evolving HLHS fetuses and the Fontan procedure in pediatric HLHS patients. Among evolving HLHS fetuses, the FAV procedure had a mortality rate of 0.18 (95% CI 0.07-0.29) and a procedural success rate of 0.81 (95% CI 0.78-0.85). In pediatric patients with evolved HLHS undergoing the Fontan procedure, the mortality rate was 0.13 (95% CI 0.00-0.25), and the procedural success rate was 0.93 (95% CI 0.85-1.00).
Conclusion: The Fontan procedure has shown better results than FAV, likely due to interstage procedural interventions and more established techniques for reducing morbidity and mortality in HLHS patients.
Ocular problems among divers: a systematic review
Authors: Dwianggita Priscilla , Juliari I Gusti Ayu Made , Pramita Ida Ayu Ary , Wirawan I Made Ady
Published: September 2024

Background: Scuba diving has been associated with various ocular conditions, affecting divers of all skill levels, from beginners to experienced individuals. Barotrauma, often caused by mask squeeze, is a well-documented issue in diving. Understanding the common eye problems divers encounter is crucial to ensure divers can take necessary precautions and safeguard the health of their eyes during and after dives. We conducted a systematic review to evaluate the various ocular problems that divers may face, explore their underlying causes, discuss preventive measures, and outline potential treatments.
Methods: A systematic review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) from the PubMed and Cochrane Library databases. Study quality and risk of bias were assessed using a checklist from Joanna Briggs Institute (JBI).
Results: We included 10 kinds of literature from all over the world, mostly originating in the United States region. The most common ocular problems are subconjunctival hemorrhage, proptosis, periorbital swelling and ecchymoses, and diplopia. More serious cases, such as intraorbital hemorrhage, proptosis, central retina artery occlusion, and optic nerve avulsion, were also reported.
Conclusions: Understanding and addressing divers' ocular problems is essential to protecting their eye health and enhancing their diving experience. By implementing preventive measures, divers can effectively mitigate the risks and promote the overall well-being of their eyes while immersing themselves in the wonders of the underwater world.
Perdarahan subdural spontan pada dewasa muda : Laporan kasus dan tinjauan literatur
Authors: Yuliantini Ni Nyoman , Putri Dian Kusumastuti Anggraeni , Suputra Gede
Published: September 2024

Introduction: Subdural hematoma (SDH) commonly occurs due to severe head trauma but can also occur spontaneously. Spontaneous SDH in young adults is a rare case because it generally occurs in old age due to brain atrophy, which increases the risk of bridging vein rupture.
Case report: A 23-year-old man was taken to the emergency room with complaints of decreased consciousness. He had a history of headaches in the last 6 days, which did not improve with analgetic. There is no history of previous trauma. Physical examination found GCS E2V2M4, anisocoric pupils, and no lateralization of muscle strength. A non-contrast head CT shows SDH in the right fronto-temporo-parietal region, which caused the subfalcine herniation to the left as far as ±1.3 cm. He underwent a hematoma evacuation with cito decompressive craniectomy and external ventricular drainage. His condition improved after surgery.
Conclusion: Spontaneous SDH in young adults is quite a rare case and the diagnosis is often delayed because the initial symptoms are not typical. Based on several case reports, spontaneous SDH in young adults can occur due to coagulopathy, arteriovenous malformations, aneurysms, intracranial hypotension, arachnoid cysts, or drug abuse such as cocaine and amphetamines. The etiology in this case is still unclear, so further investigation is necessary to reduce the risk of recurrent bleeding.
 
Pendahuluan: Perdarahan subdural biasa terjadi akibat trauma kepala yang berat, namun dapat juga terjadi secara spontan. Perdarahan subdural spontan pada dewasa muda merupakan kasus yang jarang, karena umumnya terjadi pada usia tua akibat atrofi otak yang meningkatkan risiko rupturnya bridging vein.
Laporan Kasus: Laki-laki usia 23 tahun dibawa ke IGD rumah sakit dengan keluhan penurunan kesadaran. Pasien riwayat mengeluhkan nyeri kepala sejak 6 hari sebelumnya yang tidak membaik dengan antinyeri. Pasien tidak ada riwayat trauma sebelumnya. Pemeriksaan fisik didapatkan GCS E2V2M4, pupil anisokor, dan kesan lateralisasi tenaga tidak ditemukan. CT scan kepala tanpa kontras didapatkan perdarahan subdural pada regio fronto-temporo-parietal kanan yang menyebabkan subfalcine herniasi ke kiri sejauh ±1,3 cm. Pasien dilakukan evakuasi hematoma dengan dekompresi kraniektomi dan pemasangan external ventricular drainage cito. Kondisi pasien membaik pasca tindakan pembedahan.
Kesimpulan: SDH spontan pada dewasa muda merupakan kasus yang cukup jarang, penegakkan diagnosis seringkali terlambat karena gejala yang tidak khas. Berdasarkan beberapa laporan kasus, SDH spontan pada dewasa muda bisa terjadi akibat koagulopati, malformasi arterivena, aneurisma, hipotensi intrakranial, kista arachnoid, atau penyalahgunaan obat-obatan seperti kokain dan amfetamin. Etiologi pada kasus ini masih belum jelas, sehingga perlu dilakukan penelusuran lebih lanjut untuk mengurangi risiko perdarahan berulang.
Revision mastoidectomy in a patient with unsafe Chronic Suppurative Otitis Media (CSOM): a case report
Authors: Swardyana I Nyoman , Setiawan Eka Putra
Published: September 2024

Background: Chronic suppurative otitis media (CSOM) with cholesteatoma can locally be destructive. Radical mastoidectomy is a procedure to clean and remove all cholesteatoma. However, there is a 38-60% chance of recurrence after the procedure, and the subsequent intervention is a more difficult and risky revision mastoid operation. In this study, we reported a 56-year-old woman with an unsafe type of CSOM who underwent revision radical mastoidectomy.
Case Presentation: A 56-year-old woman presented with complaints of discharge accompanied by a hole in the left ear. The patient had previously undergone ear surgery about four years ago for similar complaints. Physical examination showed a full ear canal on the left with secretions, and the tympanic membrane was difficult to assess. A head CT scan result was suggestive of chronic mastoiditis with cholesteatoma. The patient was treated with revision radical mastoidectomy and had a good outcome.
Conclusion: In conclusion, this case report presents a 56-year-old woman with recurrent unsafe type CSOM who underwent revision mastoidectomy and had a good outcome. Causes of surgical failure include a high facial ridge and inadequate meatoplasty.
Profil pasien selulitis erisipelas di Poliklinik Kulit Dan Kelamin Rumah Sakit Prof. I.G.N.G. Ngoerah periode Januari 2019 – Desember 2021
Authors: Devi Putu Akopita , Rusyati Luh Made Mas , Setyawati Ni Kadek , Adelia Martalova AJ  , Sutiawan Indry Salonika , Setyono Alfred
Published: September 2024

Introduction: One of the common manifestations of skin infection is pyoderma, which includes cellulitis and erysipelas. Data on the profile and characteristics of erysipelas and cellulitis in Indonesia are still very limited. Nevertheless, the morbidity and mortality rates caused by these diseases continue to increase the clinical burden and healthcare costs.
Method: This study is a retrospective descriptive study with a cross-sectional design, conducted by collecting secondary data from patient medical records at Prof. I.G.N.G. Ngoerah General Hospital from January 2019 to December 2021.
Result: Based on this study, there were 436 research samples that met the inclusion criteria. From 2019 to 2021, the age criteria were dominated by patients aged 41-50 years, predominantly male, most of whom were married, and the majority had no specific comorbidities.
Conclusion: Cases of cellulitis were more frequent than erysipelas, with the most common predilection being the lower extremities. The main treatment administered was 2 grams of ceftriaxone intravenous.
 
Pendahuluan: Salah satu manifestasi infeksi pada kulit yang umum ditemukan adalah pyoderma, yang mana selulitis dan erisipelas termasuk didalamnya. Data profil serta karakteristik erisipelas dan selulitis di Indonesia masih sangat terbatas. Meskipun demikian, angka morbiditas dan mortalitas yang ditimbulkan akibat penyakit-penyakit ini terus memperberat beban klinis serta biaya kesehatan.
Metode: Penelitian ini adalah penelitian deskriptif retrospektif dengan desain cross-sectional, yang dilakukan melalui pengambilan data sekunder dari rekam medis pasien di RSUP Prof Ngoerah, dalam periode Januari 2019 – Desember 2021.
Hasil: Berdasarkan penelitian ini, terdapat 436 sampel penelitian yang memenuhi kriteria inklusi. Berdasarkan kriteria usia tahun 2019–2021 didominasi oleh pasien dalam rentang usia 41 – 50 tahun, berjenis kelamin laki – laki, sebagian besar telah menikah, sebagian besar tanpa komorbid tertentu.
Simpulan: Kasus selulitis lebih sering kejadiannya dibandingkan dengan erisipelas, dengan predileksi tersering pada ekstremitas bawah. Tatalaksana utama pengobatan adalah seftriakson 2 gram IV.
Decellularization of macroalgae Eucheuma cottonii: A potential cellulose-based biomaterial for tissue engineering
Authors: Kerans Fransiscua Fiano Anthony , Dewi A. A. Ayu Asri Prima , Witari Ni Putu Diah , Kurniawati Ida , Sumadewi Komang Trisna , Evayanti Luh Gde , Astini Dewa Ayu Agung Alit Suka
Published: September 2024

Introduction: The success of tissue engineering depends on the characteristics of three-dimensional (3D) scaffolds, such as mechanical strength, porosity, and biocompatibility. These scaffolds are essential both in vitro and in vivo, as they better replicate the natural extracellular matrix (ECM). Cellulose, abundant in nature, is a prime candidate due to its biocompatibility, adaptable biomechanical properties, and cost-effectiveness. It has been explored for applications for cardiac, cartilage, and bone tissue engineering. This study aimed at the macroscopic and microscopic characteristics of decellularized Eucheuma cottonii using SDS (sodium dodecyl sulfate) to assess its potential as a tissue engineering scaffold.
Methods: Macroalgae Eucheuma cottonii were cut into small pieces and then immersed in three different concentrations of SDS solution, namely 0.1%, 0.5%, and 1%. The samples were then agitated using a rotary shaker at 160 RPM for four days. The decellularized macroalgae were processed histologically and stained with Hematoxyline-eosin (H&E). In addition, microscopic characterizations were also assessed via Scanning Electron Microscope (SEM) analysis.
Results: The results indicated the absence of nuclei or cellular contents with intact ECM, confirming acellular microarchitecture, in the decellularized Eucheuma cottoni with 1% SDS. Remarkably, SEM analysis also revealed the porous structure of decellularized Eucheuma cottonii with pore sizes ranging from 5 to 30 μm.
Conclusion: This preliminary study demonstrated the potential of decellularized macroalgae as alternative nature scaffolds. Decellularized Eucheuma cottonii tissues are expected to be cellulose-based biomaterials for candidate biomedical applications in vitro and in vivo in future studies.
Complication acute limb ischemia in a COVID-19 confirmed patient
Authors: Sugitha Komang Siska Lestari , Somia I Ketut Agus , Rena Ni Made Renny Anggreni
Published: September 2024

Introduction: COVID-19 is a condition carried upon by those infected with the SARS-COV-2 coronavirus. Hypercoagulability is one of the many signs of COVID-19. Although the etiology leading to this hypercoagulable state remains unclear, some studies have suggested that it may be linked to alterations in prothrombic factors and the disease's cytokine storm.  One of the uncommon side effects brought on by a sudden drop in arterial limb perfusion is acute limb ischemia (ALI).
Case description: A 64-year-old woman confirmed COVID-19 patient who has acute limb ischemia on the right lower extremities and is in serious condition. The patient had an above-knee amputation in addition to a thrombectomy.
Conclusion: Acute limb ischemia is a threatened life condition that the presence of COVID-19 can aggravate. Early diagnosis and treatment of this therapy are necessary for a good prognosis.
Subclavian artery pseudoaneurysm after penetrating chest trauma: A case report
Authors: Mohamad Rizki  , Soebroto Heroe
Published: September 2024

Introduction: Subclavian artery pseudoaneurysm is a rare entity with significant mortality and morbidity. Most injuries were related to iatrogenic manipulations, but in some cases, this injury has been described as secondary to a chest trauma. This case report presents a case of a subclavian artery pseudoaneurysm caused by a chest stabbing trauma.
Case description: This case is the report of a twenty-four-year-old man with a chief complaint of a painful and pulsating mass on the right shoulder 3 months before admission at the scar on his chest after having penetrating chest trauma; he also complained about weakness on the right arm. An evaluation with thorax MSCT and CT angiography supports the diagnosis of the right subclavian artery pseudoaneurysm. Intraoperative, we found a fistula from the right subclavian artery with hematomas. From the post-operative evaluation, the patient showed motoric improvement in the right arm and no pain. The patient was discharged from the hospital on the ninth day after surgery.
Conclusion: Prompt and accurate diagnosis is crucial in subclavian artery pseudoaneurysm for determining the appropriate therapeutic approach, both in surgical preparation and intraoperative focus.
Devising an integrated methodology for energy safety assessment at an industrial power-generating enterprise
Authors: Prokhorova Viktoriia , Budanov Mykola , Budanov Pavlo
Published: September 2024

This paper’s research object is a process of estimating the level of energy safety at an industrial enterprise within an electricity-power system at a microeconomic level. The task to estimate the energy safety of an industrial enterprise was solved on the basis of a combined method for the continuous monitoring of threats under an automated mode to the hour, in order to make management decisions related to reducing the influence of threats to energy safety.
Analysis of known methods for investigating the state of energy safety was performed, which revealed the lack of continuous control over the dynamic state of research objects, as well as the complexity in objectivity when giving exact and reliable primary information to calculate indicators-indexes.
It has been shown that the use of the combined approach could underlie the development of methodology for estimating the energy safety of industrial power-generating enterprise.
Such approach involves comprehensive combination of logical methods when implementing continuous monitoring of technological parameters at generation, transmission, distribution, and energy consumption facilities.
The process of choosing the objects of research and criteria for describing their properties and functions has been substantiated, in order to build the system of indicators-indexes when estimating the level of enterprise energy safety.
It has been shown that a computation algorithm makes it possible to monitor the dynamics of changes in indicators and take a management decision to eliminate energy safety threats, which leads to a reduction in economic losses in the amount exceeding USD 150,000.
Practical significance of the current research relates to the fact that the results could be used by enterprises (public authorities) for determining obstacles on a way to reducing the consumption of power resources and devising a set of organizational-economic measures
Identification of patterns of the stress-strain state of a standard plastic tank for liquid mineral fertilizers
Authors: Tyukanko Vitaliy , Demyanenko Alexandr , Semenyuk Vladislav , Alyoshin Dmitriy , Brilkov Stanislav , Litvinov Sergey , Shirina Tatyana , Akhmetzhanov Erlan
Published: September 2024

In this study, using the method of probabilistic deterministic planning (PDP), the optimum design parameters of a standard polyethylene tank used worldwide for transporting liquid mineral fertilizers (LMF) were determined.
By the finite element method, the effect of the density of liquid mineral fertilizer, tank wall thickness and four motion modes (braking, acceleration, jump and landing) on the strength of standard polyethylene tanks was studied. According to the results of the study, the five most informative areas in the tank design were identified, for which the values of maximum stresses (σmax) were obtained: filler neck, pockets, walls, tap-in points and wall transition to the tank roof. As the LMF density increases, σmax in the tank increases linearly. Increasing the tank wall thickness by 1.5 times reduces the maximum stresses by 30 to 50 %. It was found that motion mode has a significant effect on the stress-strain state of a standard tank. The “heaviest” mode for a standard tank is “braking”. The “acceleration” motion mode causes σmax of no more than 60 % of the “braking” mode values. The “lightest” mode is “landing”, in which σmax is no more than 28 % relative to “braking”. Based on the PDP method, equations were derived for calculating maximum stresses depending on LMF density, wall thickness and motion mode of the tank. Nomograms were built that make it possible to quickly determine the wall thickness of a standard tank without calculations, depending on external factors. The results of the study can be used in practice when designing safe and durable tanks for transporting liquid mineral fertilizers.
Mathematical and computer identification of the characteristics of oscillation frequency and deformations of the equipment element in the flush purification unit
Authors: Surzhko Tetiana , Molchanov Petro , Hudz Serhii , Knysh Maksym , Sribna Yuliya , Hrytsenko Larysa , Tytarenko Valerii , Savyk Vasyl , Rubel Victoriia
Published: September 2024

The object of research is an element of equipment in a vibrating screen, which is an active working body in the form of a plate.
The key element in the system of the flush purification unit is the vibrating screen. The basic design of the sieve does not allow the flush solution to be distributed evenly over the entire working surface. The concentration of drilling fluid in the central part of the equipment leads to premature abrasive wear and failure of the working element. Therefore, the structure of the vibrating screen needs to be improved in order to extend its service life. This task has been solved through the introduction of an active element to the structure for the redistribution of the solution through additional transverse vibrations.
The use of such an active element is an important step for improving the quality and efficiency of the purification system, which could optimize production processes and reduce costs in industry.
Taking into account transverse vibrations and calculating frequency parameters could help improve the design and use the vibrating screen more productively.
An analysis of the frequencies of oscillations of the active element-plate for cleaning the flush liquid with a vibrating screen was performed and a comparison of the analytically obtained results with the simulation data using the finite element method in the COMSOL Multiphysics software was carried out. The results are the basis for designing vibrating screens, conducting experimental and industrial research, and testing the screens. Computer studies have confirmed the possibility of using the improved design of the vibrating screen. By comparing the results of the calculation and computer simulation, the error was determined to be within 5 %.
The identified patterns could make it possible to select the plate oscillation frequencies depending on the known initial parameters, which would be useful for solving similar tasks.
Assessing the efficiency of using precision farming technology and remote monitoring of weather conditions in the activities of agricultural enterprises
Authors: Neftissov Alexandr , Biloshchytskyi Andrii , Andrashko Yurii , Vatskel Volodymyr , Toxanov Sapar , Gladka Myroslava
Published: September 2024

The object of this study was the technology of precision agriculture and remote monitoring of weather conditions. The task to evaluate the effectiveness of using precision farming and precision irrigation technologies in the activities of agricultural enterprises under different conditions, in particular, different climatic and weather conditions, has been considered. To solve the task, a hardware-software system for smart irrigation and remote monitoring of weather conditions in the activities of agricultural enterprises during the cultivation of agricultural crops was designed and described. Results of the system's performance were analyzed in the activities of the Ukrainian agricultural company, which grew potatoes of various varieties in the Kyiv oblast (Ukraine) from 2021 to 2023. The results show that the average yield of potatoes of different varieties without irrigation for three years of observation was 29.74 t/ha, with irrigation – 48.99 t/ha, and with smart irrigation – 55.26 t/ha. At the same time, in the latter case, water, human, and financial resources were saved. The increase in yield with smart irrigation compared to yield with conventional irrigation over the three years of observation was on average 12.8 %. According to the results of the implementation of the hardware-software system for smart irrigation and remote monitoring of weather conditions in Ukraine, the effect of the possible implementation of this system by agricultural companies in the Republic of Kazakhstan was analyzed. The forecast of the average yield of potatoes for the period from 2024 to 2026 was built based on the model of linear weighted moving average, taking into account corrections in the case of using smart irrigation. Data on potato yield from 1990 to 2023 were chosen as the basis. The use of smart irrigation according to the described technology could increase the yield of potatoes of various varieties on average from 31.71 t/ha to 35.78 t/ha in comparison with the forecast values of yield without irrigation at the level of 19.25 t/ha. This confirms the need to apply the transfer of precision farming technologies to increase the yield of agricultural crops, in particular potatoes, and the productivity of agricultural companies
Development of an innovative patch antenna design and implementation using ENG materials for health care systems and 5G networks
Authors: Nagima Bakirova , Kumar Pramod , Suman Nelaturi , Serikov Tansaule , Temirbekova Marzhan , Sergazin Gani , Mussapirova Gulzada , Arai Tolegenova , Tlenshiyeva Akmaral , Kassym Ruslan
Published: September 2024

The object of this study is a new design of an overhead microstrip antenna, including Epsilon Negative (ENG) metamaterials and L-shaped parasitic overlays aimed at achieving dual-band operation and improving the performance of modern wireless communication systems. The research is aimed at solving the problem of limited bandwidth and dual-band functionality in conventional antenna designs.
This study solves the problem of limited bandwidth and dual-band functionality in conventional microstrip patch antenna designs, which are crucial for modern wireless communication systems. The inclusion of L-shaped parasitic overlays effectively expands the bandwidth in each frequency range.
The results indicate significant improvements: at the upper resonant frequency, a 10 dB return loss bandwidth of 27.84 % (2.88–3.81 GHz) and a 3 dB axial ratio bandwidth of 5.05 % (2.90–3.05 GHz) are achieved, while at the lower resonant frequency, a return loss bandwidth is 10 dB, which is 6.11 % (2.22–2.36 GHz). These improvements indicate a significant increase in antenna performance compared to conventional designs, which is confirmed by comparing the simulation results with the measurement results.
Distinctive features contributing to these results include the use of ENG metamaterials, which improve electromagnetic properties and signal propagation; vertical transitions, which provide efficient dual-band operation; and L-shaped parasitic overlays, which significantly expand bandwidth. These characteristics combine to eliminate the limitations of traditional designs, which makes the proposed antenna suitable for use in a wide frequency range in modern wireless communication systems.
Minimizing sweet cherry fruit losses during storage under the influence of hydrocooling and protective organic composition
Authors: Ivanova Iryna , Serdyuk Marina , Tymoshchuk Tetiana , Malkina Vira , Zinovieva Olha , Lisohurska Dina , Nevmerzhytska Olha , Lisohurska Olha
Published: September 2024

Reducing fruit losses is one of the most important strategies for improving diets and strengthening food systems. Therefore, improving modern technologies for storing sweet cherries, assessing the potential of the necessary capacities and technologies for fruit storage to reduce post-harvest losses and extend the shelf life of fruits remains relevant. Improvement of pre-cooling methods optimize the shelf life of fresh fruit and contributes to the growth of demand for fruit by consumers in the European market. The object of the study is the technology of pretreatment of sweet cherry fruits using an organic composition. The fruits of the model variety Valerii Chkalov were used as experimental material.
The minimum natural losses from microbiological diseases and physiological disorders were recorded on the 40th day of sweet cherry fruit storage. Fruit weight losses during storage of sweet cherries of the Valerii Chkalov variety were minimal when hydro cooling was applied in combination with a protective organic composition of lactic and acetic acid (1.75 %:2.00 %). The optimum concentration of lactic and acetic acids (2.00 %:1.75 %) was determined, which ensures minimal daily fruit losses (0.068 %) under the influence of hydro-cooling during storage of sweet cherries. The analysis of the regression model reveled the optimal value of the average level of daily losses during storage of sweet cherry fruit of Valerii Chkalov variety – 0.0642 % at concentrations of lactic and acetic acid 2.161 % to 1.705 %, respectively. The tendency to minimize sweet cherry fruit losses during storage under the influence of hydrocooling and the optimal concentration of organic acids in the protective composition was identified. The results could be used to improve pre-cooling methods in the food industry to preserve the quality of fruit raw materials in a waste-free fruit supply chain for all relevant stakeholders
Improving regulatory directions for financial stimulation of innovative investment in the European Union
Authors: Hnatkivskyi Bohdan
Published: September 2024

The object of this study is the existing systems of regulatory identification of forms and methods of financial support and stimulation of innovative investment within the European Union. For the purposes of the study, existing approaches to determining the content of state policy in the field of innovative investment within the European Union were summarized. The existing methods and procedures of financial stimulation and innovative investment have been studied, their advantages and disadvantages were determined. It was established that the existing systems of support for innovative investment do not fully meet the needs of participants in innovative relations. The expediency of improving the existing methods of regulatory fixation of methods of financial stimulation of innovative investment is substantiated. The concept of the structure of the regulatory policy of innovative investment within the European Union has been proposed. Directions for improving current international agreements and treaties of the European Union in the field of innovative investment have been formed in the part related to the formation of a system of means of financial stimulation of innovative investment. An indicative system of promising means, methods, and techniques of financial stimulation of innovative investment has been defined.
The research is aimed at the formation of general theoretical foundations for improving the regulatory system of innovative investment, as well as the analysis and systematization of existing methods and techniques for identifying means of financial support for innovative investment. The research results could be used in the formation of international regulatory acts, acts of the national level, and serve as a basis for further scientific research on these issues
Revealing patterns in reducing the fire-hazardous properties of insulation made from plant raw materials
Authors: Tsapko Yuriy , Tsapko Аleksii , Prisyazhnuk Vitally , Klymas Ruslan , Likhnyovskyi Ruslan , Slutskaya Oksana , Lialina Natalia , Kaveryn Kostiantyn
Published: September 2024

An issue related to the use of hemp bundle insulation for building structures is to ensure their fire resistance under the action of a low-calorie ignition source. Therefore, the object of research was the change in the properties of the insulation during fire protection with its compositions capable of forming a layer of pinocoke under the influence of high temperature. On the basis of experimental data, it was established that at fire protection of insulation with a fire retardant agent, hydrolytic stable ethers containing phosphorus and nitrogen atoms are formed on the surface of the fibers. According to the temperature values and the shape of peaks on the DTA curve, it was established that at fire protection, the height of the peaks decreases and the width increases, which characterize the flow of exothermic transformations and the destruction of hemp fibers. At the same time, it was established that the formed residue has 13.3 % for impregnation and 26.6 % for coating. It has been proven that in the process of thermal action on the fire-resistant coating, the heat insulation process of the insulation consists in the formation of soot-like products on the surface of the material. So, it was determined that the sample did not catch fire, it was charred in the place of the radiation panel, and the burning was not recorded. On the other hand, for a sample of insulation treated with a coating during thermal action, the formation of a heat-insulating layer of foam coke occurred, which inhibits the penetration of heat, the temperature of flue gases did not exceed 100 °C, and the flammability index was 0. The practical significance is that the results were taken into account when designing buildings and structures. So, there are reasons to assert the possibility of targeted regulation of fire protection processes of insulation by applying coatings that form a protective layer on the surface of the material
Identifying the impact of absorptive capacity, new product development, and marketing capabilities on digital marketing adoption and new product performance in Indonesian SMEs
Authors: Yulianto Edy , Supriono Supriono , Bafadal Aniesa Samira
Published: September 2024

This study investigates the impact of absorptive capacity on enhancing the performance of SMEs through new product development, marketing capabilities, and the adoption of digital marketing. The research problem addresses how absorptive capacity influences these factors to improve new product performance. A quantitative approach was employed, collecting data from 212 SMEs in three cities in East Java Province, Indonesia. Data analysis was conducted using Partial Least Squares Structural Equation Modeling (PLS-SEM). The results indicate that critical factors influencing new product performance include the ability of SMEs to absorb external knowledge (indicator AC3, loading factor 0.852), new initiatives in product development (indicator NPD4, loading factor 0.886), and strong marketing strategies (indicator MC3, loading factor 0.878). Further analysis reveals that absorptive capacity positively and significantly affects new product development (ß=0.763; p-value<0.05) and marketing capabilities (ß=0.724; p-value <0.05) but has a negative and insignificant effect on digital marketing adoption (ß=–0.102; p-value>0.05). However, digital marketing adoption positively and significantly impacts new product performance (ß=0.628; p-value<0.05). These findings suggest that while absorptive capacity is crucial for new product development and marketing capabilities, it is insufficient to drive digital marketing adoption. The results highlight the important but not significant mediating role of digital marketing adoption. The practical implications provide guidance for SMEs to adjust their marketing strategies and new product development to improve performance, particularly during a crisis
Substantiating the feasibility of using hemp seed protein in cooked sausage technology
Authors: Pasichnyi Vasyl , Shevchenko Oleksandr , Tischenko Vasyl , Bozhko Nataliia , Marynin Andrii , Strashynskyi Igor , Matsuk Yuliiа
Published: September 2024

The object of this study was the technology of cooked sausages with hemp seed protein. The research considers determining the effectiveness of using protein from hemp seeds in the technology of cooked sausages to increase the nutritional value and improve the functional and technological indicators when replacing part of the meat raw material. The subject of the research was meat model systems, cooked sausage with hemp seed protein.
Three prototypes of cooked sausages based on the analog were developed. In experimental samples of cooked sausages, second-grade beef was replaced with protein from hemp seeds (Cannabis Sativa L.) (ToV "Desnaland", Ukraine) in amounts of 12, 14, and 16 %. The functional and technological indicators of hemp seed protein were previously investigated at hydromodules of 1:1, 1:2, and 1:3. It was found that hydrated hemp seed protein in a ratio of 1:1 had the best parameters for introduction into minced meat systems.
It was determined that the introduction of proteins from hemp seeds (hydromodule 1:1) in the amount of 12–16 % increases the water-binding capacity of minced meat to 97.8 %, plasticity by 16.19–23.85 %, and the content of total moisture in samples of cooked sausages after heat treatment by 5.08–7.08 %, yield of the finished product up to 129.83 %. Replacing second-grade beef in cooked sausage with protein from hemp seeds causes an increase in the mass fraction of protein in finished products by 14.99–19.98 %, and mineral substances by 68.52–97.22 %. The organoleptic indicators of the experimental cooked sausages met the regulatory requirements. The safety of the developed products was established according to microbiological indicators.
It has been proven that the use of hydrated protein from hemp seeds in the technology of cooked sausages in the amount of 12–14 % makes it possible to obtain a meat product with a high level of functional and technological indicators of model meat systems and organoleptic indicators of finished products. The use of protein from hemp seeds in the production of cooked sausages makes it possible to expand the range of products popular among the population
Integration of the legal conception into legislation and social reality
Authors: Bedrii Marian
Published: September 2024

The article is devoted to the issues of implementing a legal conception into legislation and social reality. Specifically, it explores the path that legal conceptions take from their creators' consciousness to legal doctrine, lawmaking, and law enforcement. The oral or written publication of a concept elicits an appropriate response from the environment – positive, negative, neutral, or mixed. The recognition of a legal conception determines its integration into legal doctrine (an indicator of such recognition is primarily citation). It is emphasized that legal concepts are vulnerable to plagiarism, as copyright law excludes concepts from the scope of its legal protection.
From legal doctrine, a legal conception moves into the normative base and practical realm. Generally, it initially enters legislation and then societal reality, but there are exceptions. For instance, the history of Ukrainian law knows other cases where a legal conception was implemented in societal life without prior integration into legislation. A recognized legal conception can determine the content of all or specific provisions of a law (including the constitution or code), international treaty, subordinate normative-legal act, interpretative act of a constitutional jurisdiction authority, judicial or administrative decision, etc.
A legal conception, projected onto social relations through the intermediary of legislative text, is usually not fully reflected in them. It should be understood that the norm of the legislation is applied in social life, and its content in most cases corresponds to the provisions of the concept partially and limitedly. The brevity and fragmentary nature of the text of a normative-legal act sometimes lead to misunderstanding or incorrect application of the concept's provisions, on which it was based.
Specific examples of the influence of legal conceptions on legislation and social practice in Ukraine and other countries are highlighted. The example of H. Kelsen and the historical significance of his conception of constitutional justice are considered. Certain directions of influence on the modern legal system of Ukraine by scientific conceptions of representatives of the Faculty of Law of Ivan Franko National University of Lviv are shown
Problems of criminal responsibility for illegal deportation of children
Authors: Politova Anna
Published: September 2024

This article is concerning on the actual problem of criminal responsibility for illegal deportation of children. It has been stressed by the author that illegal deportation of children is of particular concern, although it is almost impossible to document and establish the total number of such cases at the occupied territories. Certain problems arise in the qualification of such encroachments under the Criminal Code of Ukraine, which should be taken into account when developing the draft of a new one.
An emphasis has been made upon the definition of the term of “child” in international law and national legislation. It has been established that international law has a clear mechanism for the protection of children’s rights against illegal displacement or deportation. It has been also noted that the national legislation has an acute problem in the regulation of the use of the terminology “deportation”, “forcible displacement” and “illegal removal” and the definition of criteria for their distinction.
An analysis of the provisions of the drafts of Law of Ukraine “On Amendments to the Criminal Code of Ukraine and other legislative acts of Ukraine regarding forcible displacement of a person in conditions of armed aggression” (Reg. No. 8326 dated 12/30/2022) and Law of Ukraine “On Amendments to the Criminal Code of Ukraine regarding forcible displacement of a person outside the territory of Ukraine” (Reg. No. 9204 dated 04/13/2023) has been made, their shortcomings have been indicated.
It has been demonstrated that the Article 11.5.11. “Illegal abduction of a child” of the draft of the Criminal Code refers to the abduction of a child. The main direct object of such criminal act is the freedom of the child, which proves that this act cannot be attributed to Book Eleven. “Crimes against the international legal order” of the draft of the Criminal Code.
Based on the results of the study, it has been concluded that the illegal deportation of children poses a threat to the national security of Ukraine; the necessity of further scientific development of this issue has been augmented
Legal regulation of vacations of medical workers in Ukraine according to labor legislation
Authors: Teremetskyi Vladyslav , Rusnak Lesya
Published: September 2024

The relevance of this scientific research lies in clarifying the nature and features of the legal regulation of vacations for medical workers in Ukraine. The purpose of this study is to determine the specifics of the legal regulation of the types of vacations that may be granted to medical workers. The methodological basis of the study was general scientific and special legal methods of knowledge, in particular theoretical, formal, dogmatic, and comparative legal methods.
The results of the study are that the rest time of a medical worker is proposed to be understood as a period of release from professional duties for the restoration of work capacity and professional development. Several features of the legal regulation of medical workers’ vacations have been identified.
Please note that additional vacation may be assigned to medical workers of various specialties along with the main vacation. Additional vacations lasting 7 to 25 days are granted to medical workers of certain specialties who work in certain healthcare institutions due to harmful or special working conditions. Additional vacations are established for such medical workers as psychiatrists, pathologists, resuscitators, anesthesiologists, obstetricians, epidemiologists, doctors of medical and social expert commissions, bureaus of forensic medical examinations, and health care institutions for the fight against AIDS. It is emphasized that specific categories of medical workers have the right to additional vacation in connection with the experience of continuous work in rural areas or at another place of work. Also, medical workers have the right to use all types of additional social vacations, established for all categories of workers in Ukraine.
The study concludes that a special Ukrainian law "On the Status of Medical Workers" would improve the legal regulation of medical workers’ labor relations. Taking into account the provisions of the current legislation, an author’s definition of the term "medical worker" has been formulated
Evolution, mechanism of action, and clinical applications of three generations of Antihistamines
Authors: Lisiecka Maria Zofia
Published: September 2024

Introduction. This review investigates the evolution, mechanisms of action, and clinical applications of three generations of antihistamines. Materials and methods: To identify relevant studies, an extensive search was performed across multiple databases, including PubMed, MEDLINE, Web of Science, and Scopus, using a strategic combination of keywords and MeSH terms. The selection process yielded relevant scientific literature sources published between 1985 and 2023. Results and discussion: the study demonstrated that the initial step in the creation and development of antihistamines involved analysing the mechanisms of anaphylaxis and allergy. This analysis led to the discovery of histamine as a mediator of allergic reactions and subsequently to the synthesis of substances with antihistamine effects, resulting in the gradual discovery of three generations of antihistamines. These drugs are designed to block H1-histamine receptors to eliminate allergic manifestations. Due to their non-selective antihistamine activity, first-generation drugs have many side effects, primarily sedation, in addition to their intended therapeutic effects. Second- and third-generation drugs are selective for peripheral H1 receptors and have significantly fewer side effects. The third generation of drugs, as active metabolites of the second generation, demonstrate the highest efficacy and safety profile. First-generation medicines are used for emergency care in acute allergic reactions and to reduce local allergy manifestations, whereas second and third generations are used to treat symptoms of seasonal and chronic allergic rhinitis. Conclusions: The significance of the study lies in the potential application of its results in the clinical practice of allergists.