bluuebunny/crossref_metadata_2025 huggingface dataset:
Normas para la presentación de informes de investigación y artículos científicos
Authors: Paba Barbosa Carmelina , Paba Argote Zuany Luz , Vega Villa David Felipe , Ceballos Ospino Guillermo Augusto
Published: May 2021

En la actual edición se presentan y explican diversos aspectos fundamentales para la redacción de manuscritos que cumplan con parámetros, normas y criterios eficientes relacionados con la escritura académica y científica. Este libro está dirigido a estudiantes y profesores con el fin de que les permita la posibilidad de mejorar sus procesos de producción textual en el contexto académico y científico en el que enfrentan actividades y exigencias de alta calidad escritural. Para tal propósito se han actualizado y ampliado apartes en su contenido, tales como orientaciones generales de redacción para utilizar diversos mecanismos básicos de redacción; también se presentan diversas recomendaciones acerca de la macro y microestructura textual, así como recursos de cohesión y coherencia. De otra parte, se ofrece una explicación detallada sobre la estructura general de documentos de investigación y artículo científico. Además, se incluyen elementos importantes de la nueva edición de normas APA séptima edición en lo que respecta a citas y referencias bibliográficas con ejemplos de cómo hacerlo, y se incluye una nueva temática que hace referencia a aspectos relevantes en cuanto a la ética en la redacción de documentos de investigación: plagio y antiplagio. Después de un juicioso trabajo de revisión y actualización, lo invitamos a utilizarla.
Computational and Synthetic Target-based Approaches to the Discovery of Novel Anticonvulsant Compounds
Authors: Gantner Melisa Edith , Llanos Manuel Augusto , Garofalo Federico Mariano , Villalba María Luisa , Gavernet Luciana
Published: May 2021

Background:

During the past decades, an important number of anticonvulsant
drugs have been incorporated into the collection of drugs to treat epilepsy. However, two
main difficulties remain unsolved in therapy: the development of drug-resistant epilepsy
and the occurrence of severe toxic effects caused by the medication in responsive patients.
The retrospective analysis of the strategies for discovering known anticonvulsant
drugs showed that screening campaigns on animal models of epilepsy have been almost
the exclusive strategy for identifying the marketed compounds. However, the actual structural
and functional information about the molecular targets of the anticonvulsant drugs
and the increasing knowledge of the molecular alterations that generate epileptic seizures
allow a more rational identification of active compounds.

Objective:

This review compiles target-based strategies used for the discovery of new anticonvulsant
candidates and is divided in two main topics. The first one provides an
overview of the computational approaches (docking-based virtual screening and molecular
dynamics) to find anticonvulsant structures that interact with the voltage-gated ion
channels and the enzyme carbonic anhydrase. The second one includes the analysis of active
compounds synthesized to act simultaneously on different molecular targets by the
combination of pharmacophores of anticonvulsant drugs.

Conclusion:

Current knowledge of the architectures of anticonvulsant targets makes computational
simulations attractive methods for the discovery and optimization of active
compounds. Combining the results achieved by virtual screening of different targets
could lead to multitarget compounds, as an alternative to the design of structures that
merge scaffolds of known drugs.
SARS-CoV-2 Induced Neurological Manifestations Entangles Cytokine Storm that Implicates for Therapeutic Strategies
Authors: Chong Zhao-Zhong , Souayah Nizar
Published: May 2021

The new coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), can present neurological symptoms and induce neurological complications. The involvement in both the central and peripheral nervous systems in COVID-19 patients has been associated with direct invasion of the virus and the induction of cytokine storm. This review discussed the pathways for the virus invasion into the nervous system and characterized the SARS-CoV-2 induced cytokine storm. In addition, the mechanisms underlying the immune responses and cytokine storm induction after SARS-CoV-2 infection were also discussed. Although some neurological symptoms are mild and disappear after recovery from infection, some severe neurological complications contribute to the mortality of COVID-19 patients. Therefore, the insight into the cause of SARS-CoV-2 induced cytokine storm in context with neurological complications will formulate the novel management of the disease and also further identify new therapeutic targets for COVID-19.
Production of Chemotherapeutic Enzyme L-asparaginase from a Fungal Source
Authors: Pendharkar Girish B. , Sonawane Harshal G. , Khare Kalpesh A. , Yadav Dhananjay
Published: May 2021

Background:

L-Asparaginase is an antineoplastic agent used in the treatment of acute
myeloid and acute lymphoblastic leukemia. The present study deals with the production of this
chemotherapeutic enzyme drug from Aspergillus flavus NCIM 526. The production of enzymes
was carried out using oil-extracted cakes in a shake flask culture. Process parameters like carbon
and nitrogen sources were also taken into account.

Methods:

A total of six isolates were used to screen out efficient microorganisms for enzyme
production. Aspergillus flavus NCIM 526 exhibited 138 IU/ml of enzyme activity in oil extracted
mix cake after 96 hours of the incubation period. Molasses and l-asparagine were proved to be
the best carbon and nitrogen sources for enzyme production. The enzyme was purified by column
chromatography and the finest enzyme exhibited specific activity of 28 IU/mg.

Results and Discussion:

The fungal enzyme exhibited low Km values as compared with standard
E. coli L-asparaginase, proving more substrate affinity of fungal enzyme than bacterial enzymes.

Conclusion:

The study explored the Aspergillus flavus NCIM 526 as a potential fungal source
for high yield production of antileukemic enzyme drugs.
In vitro Antioxidant, α-amylase and Horseradish Peroxidase Inhibitory Potential
of Phenolics Extracts from Chamomilla pubescens, Pulicaria crispa
and Rhanterium adpressum Growing in Algeria
Authors: Mahfoudi Feriel , Reguia Mahfoudi , Harrat Mohamed , Djeridane Amar , Yousfi Mohamed
Published: May 2021

Background:

Plants are a main source of drugs for the therapy of a large number of diseases.

Objective:

The aim of the present work is to evaluate the in vitro antioxidant and anti-α-amylase and anti-peroxidases (HPR) potentials of phenolic extracts obtained from three spontaneous plants; growing in the South of Algeria such as (Chamomilla pubescens, Pulicaria crispa, and Rhanterium adpressum). This is the first report on the study of α-amylase and horseradish peroxidase (HRP) inhibitory activity for phenolic extracts from the Chamomilla pubescens and Pulicaria crispa plants.

Method:

The antioxidant activity was evaluated in vitro using four tests: DPPH, CUPRAC, FRAP, and ABTS. The phenolic, flavonoid, and tannin compounds of the three selected Algerian plants were quantified. Also, the inhibition of α-amylase and HRP was evaluated.

Results:

The quantification of the total phenolic contents revealed that they are widely variable, and depending on extraction solvents, the highest content was recorded by the ethyl acetate extract of Chamomilla pubescens (flowers) 774.93±60.14mg/100 g of dry matter. In all the antioxidant tests, ethyl acetate extracts showed the most effective activity, which the best was (VCEAC = 65.62 ±0.50 µM/g dry matter) of Pulicaria crispa for the DPPH test. Furthermore, the results of α-amylase and peroxidase inhibitory effects indicated that all plants extracts have inhibitory effects on the two enzymes, with AEIC values ranged from 76.55±3.54 to 149.54±6.68 μM/g of dry matter for the α-amylase, and CEIC values ranged from 8.89±2.22 to 9668.31±254.42 μM/g of dry matter for the peroxidase (HRP).

Conclusion:

The present study results suggest that the three Algerian spontaneous plant species (Rhanterium adpressum, Pulicaria crispa, and Chamomilla pubescens) inhibit peroxidase and α-amylase and exhibit a high antioxidant activity what can be related to the treatment of diabetes and thyroid diseases.
ANALYSIS OF FEASIBILITY OF DEVELOPMENT OF AGROPOLITAN AREA PROBOLINGGO DISTRICT
Authors: Patiung Markus
Published: May 2021

This research was conducted in Probolinggo district, East Java Province, Indonesia. The research objective was to analyze the feasibility of developing an agropolitan area from the financial and infrastructure aspects. The analytical methods used are: Revenue Cost Ratio analysis; Payback Period (PP); Net Present Value (NPV); Internal Rate of Return (IRR). The results showed that the development of the farmer's market, namely the development of the Krucil fruit and vegetable market, the construction of a flat storage market and the development of the leaning agribusiness sub-terminal, and infrastructure are very feasible to build in the context of developing an agropolitan area and need to be continued in the Detail Engineering Design (DED).
PRODUCTIVITY GAP BY GENDER AMONG RICE FARMERS IN NORTH-CENTRAL NIGERIA
Authors: Sadiq Sanusi Mohammed , Singh P I , Ahmad M M
Published: May 2021

The present research used a field survey data of 2020 rice cropping season to determine yield gap by gender among rice farmers in North-Central Nigeria. A total of 376 farmers were drawn from a sampling frame through a multi-stage sampling technique and a structured questionnaire coupled interview schedule was used for information elicitation. Both descriptive and inferential statistics were used for data analysis. The empirical evidences showed that most of the farmers have negative attitudes towards risk and this owes to poor resource capital base, thus hinders cultivation of economic holdings. Besides, women farmers were more averse to risk than the men farmers which owes largely to gender discrimination and stereotype induced by culture and religion, thus hindered their access to and control over productive resources. Furthermore, neither gender nor risk attitudinal differentials have impact on the average yield of the farmers. However, it was established that yield gap was largely due to gender and risk attitudinal discriminations. Therefore, the study enjoins the farmers, especially the women folk to harness social capital viz. participation in co-operative association- pecuniary advantages, thus enable them to have access to and control over productive. In addition, the policymakers are advised to create an enabling agricultural environment for the women folk viz. gender budget mainstreaming, thus tackling women farmers’ susceptibility to the vicious cycle of poverty.
Diagnóstico de riesgos en el sector turístico latinoamericano para el trienio 2020-2022
Authors: González-Rodríguez Julio César , Acevedo-Navas Christian
Published: May 2021

Este artículo identifica los principales riesgos que podrían generar crisis en la industria turística latinoamericana para el trienio 2020-2022, a partir de una revisión de literatura y un tanque de pensamiento con 38 expertos en seguridad, en el marco del Congreso de la Asociación Latinoamericana de Seguridad (ALAS) en Punta Cana (2020). Se establece un listado de 20 principales riesgos, sobre el cual se interrogó al grupo de expertos y se aplicó una escala de Likert para definir su importancia en función de su probabilidad o consecuencias. Como resultado, se determinó que los principales riesgos que pueden impactar el turismo son: virus y plagas, amenazas naturales, sabotajes a infraestructura crítica, inseguridad ciudadana, y escándalos y rumores. Además, el listado aumentó a 27 riesgos críticos, como referente para futuros estudios.
Comparación del acondicionamiento físico en alumnos de tres escuelas del Ejército Nacional de Colombia
Authors: Cubides-Amézquita Jenner Rodrigo , Castro-Jiménez Laura Elizabeth , García-Muñoz Ana Isabel
Published: May 2021

Una condición física adecuada es fundamental para el desempeño y la supervivencia en operaciones militares. Por ello, este estudio evalúa el acondicionamiento físico de los militares en formación de tres escuelas del Ejército Nacional de Colombia mediante un estudio transversal, donde se midieron y compararon variables morfológicas y fisiológicas de 120 estudiantes (40 por escuela). Se evidenciaron diferencias en el consumo de VO2 mediante el test de Léger; en flexibilidad mediante el test de Sit and Reach; en fuerza prensil mediante dinamometría de mano; en tiempo de vuelo mediante plataformas de salto y en el índice de masa corporal. Aunque el plan de entrenamiento del Ejército es estándar, estas diferencias en el acondicionamiento, favorables para la escuela de soldados profesionales, se deben a su intensidad, duración y frecuencia.
La mortalidad del COVID-19 como prueba factual para fortalecer las estrategias de seguridad y defensa
Authors: Núñez-Cuevas Juan Camilo
Published: May 2021

La pandemia del COVID-19 ha generado grandes cambios políticos, económicos y sociales, por lo cual, en consecuencia, las estrategias de seguridad y defensa han enfrentado una amenaza inusual, que puede poner en riesgo soberanías, territorios y alterar el orden mundial. Esta investigación, realizada con un estudio tipo mixto con enfoque histórico, estadístico y epidemiológico observacional no experimental simulado, utiliza cinco variables independientes y una dependiente con el objetivo de comparar la mortalidad de las guerras y el terrorismo trasnacional con la de la actual pandemia, y así mismo proyectar el impacto de una eventual pandemia futura sobre dichas estrategias. Mediante esto se busca establecer una prueba factual, con sólidos argumentos, que explique la necesidad de fortalecer y replantear las estrategias de seguridad y defensa para el futuro pos-COVID.
Armonización entre derechos de menores víctimas de reclutamiento y su participación en crímenes internacionales
Authors: Villegas-Arévalo Sandra Consuelo
Published: May 2021

La situación de los menores víctimas de reclutamiento ilícito y su eventual participación en la comisión de crímenes internacionales abre un interesante debate en torno a las rutas procesales que debe afrontar luego de su desvinculación. Hay allí una tensión entre los derechos de las víctimas de dichos crímenes que el Estado debe investigar, juzgar y sancionar y los derechos que, como menor de edad, le son inherentes al menor desvinculado. Este artículo recoge una investigación jurídica sobre la necesidad de una interpretación sistemática y armónica que materialice el principio de centralidad de las victimas dentro del modelo de justicia transicional con enfoque restaurativo, con el fin de abrir una ruta procesal que garantice los derechos tanto de las víctimas de crímenes internacionales como de los menores víctimas de reclutamiento.
El helicóptero como factor decisivo para la movilidad táctica: el caso colombiano (1997-2012)
Authors: Tovar-Cabrera Gustavo Andrés , Figueroa-Pedreros Erika Constanza
Published: May 2021

Para un ejército, la movilidad es determinante para ejecutar misiones en el nivel táctico, con sus respectivos efectos en los resultados operacionales y estratégicos. Esto es especialmente primordial en la lucha contrainsurgente, dada la dificultad del terreno en el que se lleva a cabo la confrontación. Este artículo estudia el cambio en la movilidad aérea táctica del Ejército colombiano desde 1997, cuando se comenzó a incorporar helicópteros, hasta 2012. Se presentan los antecedentes del uso de aeronaves con fines militares, así como de la experiencia obtenida por Colombia en la Guerra de Corea, y luego se presentan los resultados del estudio, que muestran cómo la progresiva adquisición e implementación de helicópteros en el Ejército tuvo un impacto a favor en la confrontación armada, luego del último lustro de los noventa.
Propuesta de un modelo de medición del poder marítimo de las naciones
Authors: Vargas-Suárez Rubén Alfonso , Cuervo-Vázquez Noé , Moloeznik-Gruer Marcos Pablo
Published: May 2021

El poder marítimo de una nación es un factor crucial para su desarrollo y su seguridad, y al mismo tiempo involucra diversas variables que lo hacen un concepto relativo y complejo de comparar con los demás países de la región y el mundo. Por ello, este artículo busca proponer un modelo de medición del poder marítimo que permita evaluar los Estados, así como hacer comparaciones entre ellos. Para ello se parte de conceptos navales doctrinarios básicos, con el fin de construir definiciones claras y medibles de poder marítimo, desarrollo marítimo, seguridad marítima y poder naval, para generar los indicadores e índices necesarios que sustentan la validez y confiabilidad del modelo. Finalmente se presentan los resultados de su aplicación en una muestra global y regional.
El control de convencionalidad y las garantías jurídicas en el proceso para el subrogado penal
Authors: Ramírez-Carvajal Diana María , Paniagua-Galeano Alexander
Published: May 2021

Las tradiciones jurídicas en extremo legalistas que aún se mantienen en el proceso penal colombiano sustentan las decisiones de los jueces e impiden que se apliquen fuentes del derecho que emanan de la Constitución y de las normas convencionales y los precedentes de la Corte Interamericana de Derechos Humanos. Dado que las políticas legislativas restringen los beneficios de la pena, se debe hacer un esfuerzo por avanzar en una interpretación judicial más acorde con la humanización del proceso. Así, este artículo investiga el abanico de normas y de precedentes con que cuenta el juez penal de conocimiento para lograr los fines de la justicia en la decisión judicial, promoviendo a la vez un cambio en la vulneración masiva de derechos de las personas privadas de la libertad.
Evaluating the Impact of a Digital Nutrition Platform on Cholesterol Levels in Users With Dyslipidemia: Longitudinal Study
Authors: Hu Emily A , Scharen Jared , Nguyen Viet , Langheier Jason
Published: May 2021

Background

A strong association exists between consuming a healthy diet and lowering cholesterol levels among individuals with high cholesterol. However, implementing and sustaining a healthy diet in the real world is a major challenge. Digital technologies are at the forefront of changing dietary behavior on a massive scale, as they can reach broad populations. There is a lack of evidence that has examined the benefit of a digital nutrition intervention, especially one that incorporates nutrition education, meal planning, and food ordering, on cholesterol levels among individuals with dyslipidemia.

Objective

The aim of this observational longitudinal study was to examine the characteristics of people with dyslipidemia, determine how their status changed over time, and evaluate the changes in total cholesterol, high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), non-HDL-C, and triglycerides among individuals with elevated lipids who used Foodsmart, a digital nutrition platform that integrates education, meal planning, and food ordering.

Methods

We included 653 adults who used Foodsmart between January 2015 and February 2021, and reported a lipid marker twice. Participants self-reported age, gender, weight, and usual dietary intake in a 53-item food frequency questionnaire, and lipid values could be provided at any time. Dyslipidemia was defined as total cholesterol ≥200 mg/dL, HDL-C ≤40 mg/dL, LDL-C ≥130 mg/dL, or triglycerides ≥150 mg/dL. We retrospectively analyzed distributions of user characteristics and their associations with the likelihood of returning to normal lipid levels. We calculated the mean changes and percent changes in lipid markers among users with elevated lipids.

Results

In our total sample, 54.1% (353/653) of participants had dyslipidemia at baseline. Participants with dyslipidemia at baseline were more likely to be older, be male, and have a higher weight and BMI compared with participants who had normal lipid levels. We found that 36.3% (128/353) of participants who had dyslipidemia at baseline improved their lipid levels to normal by the end of follow-up. Using multivariate logistic regression, we found that baseline obesity (odds ratio [OR] 2.57, 95% CI 1.25-5.29; P=.01) and Nutriscore (OR 1.04, 95% CI 1.00-1.09; P=.04) were directly associated with achieving normal lipid levels. Participants with elevated lipid levels saw improvements as follows: HDL-C increased by 38.5%, total cholesterol decreased by 6.8%, cholesterol ratio decreased by 20.9%, LDL-C decreased by 12.9%, non-HDL-C decreased by 7.8%, and triglycerides decreased by 10.8%.

Conclusions

This study characterized users of the Foodsmart platform who had dyslipidemia and found that users with elevated lipid levels showed improvements in the levels over time.
Health-Related Internet Use by Informal Caregivers of Children and Adolescents: An Integrative Literature Review
Authors: Park Eunhee , Kim Heejung , Steinhoff Andreanna
Published: May 2021

Background

Internet-based health resources can support informal caregivers who are caring for children or adolescents with health care needs. However, few studies discriminate informal caregivers’ needs from those of their care recipients or those of people caring for adults.

Objective

This study reviews the literature of health-related Internet use among informal caregivers of children and adolescents.

Methods

A total of 17 studies were selected from literature searches conducted in 6 electronic databases: PubMed, Cochrane, CINAHL, PsycINFO, ERIC, and EMBASE. All databases searches were limited to articles published in the years 2004 to 2014 in peer-reviewed publications. Search terms consisted of “health-related Internet use,” “eHealth,” “Internet use for health-related purpose(s),” “Web-based resource(s),” and “online resources,” combined with informal caregiver (or “parents”) of “child,” “adolescent,” “student,” “youth,” and “teen.” The age range of the children receiving care was limited to younger than 22 years. Their informal caregivers were defined as persons (parents) who provided unpaid care or assistance to a child or an adolescent with health problems.

Results

Among 17 empirical studies, the majority of informal caregivers of children with medical issues were the parents. Quantitative studies (14/17, 77%) reported prevalence and predictors of health-related Internet use, while mixed-methods and qualitative studies (3/17, 24%) investigated informal caregiver perceptions of helpful health-related Internet use and barriers of use. The prevalence of health-related Internet use varied (11%-90%) dependent upon how health-related Internet use was operationalized and measured. Disease-specific information was used for decision making about treatment, while social support via virtual communities and email were used for informal caregiver emotional needs. A digital divide of Internet access was identified in lower educated minorities. Most studies had methodological challenges resulting from convenience sampling, cross-sectional surveys, lack of theoretical frameworks, or no clear definitions of health-related Internet use.

Conclusions

This study provides an important understanding of how family members use Internet-based information and support systems during child caregiving. Healthcare providers and policy makers should integrate family needs into their current practices and policies. Further rigorous research is required to design efficient and effective nursing interventions.
Using the Think-Aloud Method to Assess the Feasibility and Acceptability of Network Canvas Among Black Men Who Have Sex With Men and Transgender Persons: Qualitative Analysis (Preprint)
Authors: Crawford Natalie D , Josma Dorie , Harrington Kristin R V , Morris Joseph , Quamina Alvan , Birkett Michelle , Phillips II Gregory
Published: May 2021

BACKGROUND

Characteristics of an individual’s social network have been important factors in understanding infectious disease transmission patterns. Social network data collection is generally time and resource intensive, yet it is crucial to our understanding of the complex epidemiologic landscape of human behaviors among stigmatized social groups.

OBJECTIVE

We sought to evaluate the feasibility and acceptability of a self-administered social network data collection tool, Network Canvas, among Black men who have sex with men (BMSM) and transgender persons using the think-aloud method, which is a robust and flexible research technique used to perform usability testing.

METHODS

We piloted a self-administered network interview within the Network Canvas Software Suite. Participants aged 18 years and older were recruited through a community-based organization in Atlanta, GA, and were included based upon their willingness to share information on sexual behaviors and drug use for themselves and their social networks. A semistructured interview guide was used to document cognitive decision-making processes while using the tool. Recorded interviews were transcribed verbatim, and thematic analyses were performed.

RESULTS

Among 7 BMSM and transgender participants, three main themes were identified from cognitive processes: (1) the utility, (2) navigation, and (3) intuitive design of Network Canvas. Overall, Network Canvas was described as “easy to use,” with suggestions mainly directed toward improving navigation tools and implementing an initial tutorial on the program prior to use. Participants were willing to use Network Canvas to document their social networks and characteristics. In general, observed verbal responses from participants matched their behavior, although there were some discrepancies between verbal affirmations of use and understanding versus external observation.

CONCLUSIONS

We found Network Canvas to be a useful new tool to capture social network data. Self-administration allowed participants the opportunity to provide sensitive information about themselves and their social networks. Furthermore, automated name generation and visualization of an individuals’ social network in the app has the potential to reduce cognitive burden during data collection. More efficient methods of social network data collection have the potential to provide epidemiologic information to guide prevention efforts for populations with stigmatized health conditions or behaviors.
US Parents’ Acceptance of Learning About Mindfulness Practices for Parents and Children: National Cross-sectional Survey (Preprint)
Authors: Mathur Mala , Kerr Bradley R , Babal Jessica C , Eickhoff Jens C , Coller Ryan J , Moreno Megan A
Published: May 2021

BACKGROUND

Mindfulness practices are associated with improved health and well-being for children. Few studies have assessed parents’ acceptance of learning about mindfulness practices.

OBJECTIVE

This study aims to assess parents’ beliefs and interest in learning about mindfulness, including from their health care provider, and differences across demographic backgrounds.

METHODS

We conducted a national cross-sectional survey of parents with children aged 0-18 years in October 2018. Measures included beliefs and interest in learning about mindfulness. These measures were compared across demographic backgrounds using chi-square analysis. Multivariate linear and logistic regression analyses were used to perform adjusted comparisons between demographic backgrounds.

RESULTS

Participants (N=3000) were 87% (n=2621) female and 82.5% (n=2466) Caucasian. Most (n=1913, 64.2%) reported beliefs that mindfulness can be beneficial when parenting, 56.4% (n=1595) showed interest in learning about mindfulness to help their child stay healthy, and 40.8% (n=1214) reported interest in learning about mindfulness from their health care provider. Parents with a college degree 49.6% (n=444) were more likely to report interest in learning about mindfulness from a health care provider compared to those without 37.1% (n=768; P<.001). Parents interested in learning about mindfulness were more likely to be male 62.6% (n=223; P<.001). There was no significant difference in interest in learning about mindfulness from a health care provider based on race.

CONCLUSIONS

This study indicates that many parents believe mindfulness can be beneficial while parenting and are interested in learning how mindfulness could help their child stay healthy. Findings suggest there is an opportunity to educate families about mindfulness practices.
Acceptability of an mHealth App for Youth With Substance Use and Mental Health Needs: Iterative, Mixed Methods Design (Preprint)
Authors: Adams Zachary , Grant Miyah , Hupp Samantha , Scott Taylor , Feagans Amanda , Phillips Meredith Lois , Bixler Kristina , Nallam Phani Teja , La Putt Dorothy
Published: May 2021

BACKGROUND

Treating substance use disorders (SUDs) during adolescence can prevent adult addiction and improve youth outcomes. However, it can be challenging to keep adolescents with SUDs engaged in ongoing services, thus limiting potential benefits. Developmentally appropriate tools are needed to improve treatment engagement during and between sessions for youth with SUDs and mental health disorders. Mobile health apps may augment or replace psychotherapy components; however, few have been developed specifically for youth with SUDs following user-guided design principles, which may limit their appropriateness and utility. Formative research on acceptability to intended end users is needed before the efficacy of such tools can be examined.

OBJECTIVE

This study involves user-centered, iterative development and initial user testing of a web-based app for adolescents with SUDs and mental health concerns.

METHODS

Adolescents aged 14 to 17 years with past-year involvement in outpatient psychotherapy and behavioral health clinicians with adolescent SUD treatment caseloads were recruited. Across 2 assessment phases, 40 participants (alpha: 10 youths and 10 clinicians; beta: 10 youths and 10 clinicians) viewed an app demonstration and completed semistructured interviews and questionnaires about app content and functionality.

RESULTS

Participants expressed positive impressions of the app and its potential utility in augmenting outpatient therapy for youth with SUDs and mental health concerns. Noted strengths included valuable educational content, useful embedded resources, and a variety of activities. Adolescents and clinicians favored the app over conventional (paper-and-pencil) modalities, citing convenience and familiarity. The app was found to be user-friendly and likely to improve treatment engagement. Adolescents suggested the inclusion of privacy settings, and clinicians recommended more detailed instructions and simplified language.

CONCLUSIONS

The novel app developed here appears to be a promising, acceptable, and highly scalable resource to support adolescents with SUDs and mental health concerns. Future studies should test the efficacy of such apps in enhancing adolescent behavioral health treatment engagement and outcomes.
PEDAGOGICAL COMPETENCE OF TEACHERS AND STUDENTS ACADEMIC ACHIEVEMENT IN JUNIOR HIGH SCHOOLS IN ASHAIMAN, GHANA
Authors: KPORYI EBENEZER , ARKO AUGUSTUS DANIEL
Published: May 2021

The study investigated the pedagogical competence of teachers and its influence on student’s academic achievement. The descriptive survey research design was adopted and the census (all) sampling technique was used to sample 250 Junior High School (JHS) teachers in Ashaiman Municipality. The collected data from the close-ended questionnaire was analysed with mean and standard deviation on the scale of 1-4 and the Pearson’s Product Moment Correlation was used to test the hypothesis. The study revealed that as a pedagogical competence, the teachers provided appropriate feedback, adapted to changing conditions, explained content to students and communicated learning goals effectively. It was also found that there was a weak positive relationship between the classroom management competence of teachers and student’s academic achievement. The study, therefore, concluded that the pedagogical competence of teachers could help promote deep knowledge, understanding and expectation among students if teacher’s pedagogical competencies are effective. Also, when teachers increase their knowledge and competence to manage the classroom, they could provide high expectations for student’s social support, guidance and independent thought in learning. Recommendations were made to the municipal education directorate, Ghana Education Service and Ministry of Education, Ghana based on the findings.
EFFECT OF LOCKDOWN ON EDUCATION OF RURAL UNDERGRADUATE STUDENTS DURINGCOVID-19 PANDEMIC IN UMARBAN (DHAR), M.P., INDIA
Authors: Agrawal Jyoti
Published: May 2021

A survey was conducted to assess the impact of lockdown due to COVID-19 on online education of undergraduate learners of government colleges Umarban, district Dhar (454449) Madhya Pradesh, India. An online as well as offline survey was conducted from 10 October 2020 to 15 March 2021 to collect the information. To analyze the possibility and attention of students for online education, various online quizzes were conducted in which a structural questionnaire link using ‘Google form’ was sent to students through WhatsApp. A total of 265 students were taken for the survey. The simple percentage distribution was used to assess the learning status of the study participants. During the lockdown period, around 15.47% of learners were involved in e-learning. Most of the learners were used android mobile for attending e-learning. The present study revealed that around 60% of students were seen to involve in farming during lockdown instead of online classes. In addition to this, 45% of students never joined an online class during the entire session. Further analysis demonstrated that 13% of students do not have their own mobile phone, nearly 18% could not join due to poor internet connectivity, 21% of students faced unfavorable study environment at home and 3% of students have other reasons. This study also showed a comparative analysis of the presence of students before and after the COVID 19 pandemic. As the ratio of presence of students in physical and virtual classrooms was 2.32. The overall results from this study revealed that especially in rural areas COVID – 19 pandemic had affected more adversely on classroom attendance, where people already do not want to give importance to education. Higher education institutions may benefit from these findings while formulating strategies to support students during this pandemic. Moreover, to promote education in COVID 19 era strong strategies are urgently needed.
Problem Issues of Implementation of the Constitutional Right to Peaceful Assembly
Authors:   Vinnytsia National Agrarian University, Pravdiuk Andrii
Published: May 2021

The article examines the problems of constitutional and legal regulation of peaceful assemblies of citizens in Ukraine. Constitutional norms that guarantee freedom of peaceful assembly are analyzed. The primary normative documents that regulate the holding of peaceful assemblies in Ukraine are considered. The legal content of the concept of "peaceful assembly", the main approaches to its interpretation in the science of constitutional law and international legal doctrine are revealed. The importance of implementing international legal standards to ensure the right to peaceful assembly is emphasized. The necessity to adopt a special law on peaceful assemblies has been proved, enabling the regulation of the organizational and legal bases to prepare and hold peaceful assemblies of Ukraine's citizens.
Marketing of Hybrid Corn in Tapenpah Village, Insana District, North Central Timor Regency during the New Habit Adaptation Period
Authors: Siki Kanisius , Joka Umbu , Nubatonis Agustinus
Published: May 2021

The goal of this study was to determine the general definition of the marketing channel, to know the marketing roles, the marketing margins, and to use a marketing analysis to determine the price earned by hybrid corn traders. The sampling scheme was carried out by purposive sampling on hybrid corn dealers, the number of samples taken by as many as 26 respondents. The data collection tool was used to perform interviews with respondents using questionnaires. The methodological method used was the study of the marketing margin. The findings showed that the margin at the retailer level was IDR 500/kg (0.11 percent) while the retailer margin was IDR 1500/kg (0.11 percent) (0.25 percent). This means that the difference between the purchasing price and the sale price of the collector is less than the difference between the purchase price and the retail price. Since there are two elements in the marketing margin, namely the expense component and the benefit component.  Thus, the price component is IDR 4.500/kg (0.11 percent) and IDR 6.000/kg (0.25 percent) for retailers. This indicates that the market prices by the collectors are higher than the retailers
Multi-time correlations in the positive-P, Q, and doubled phase-space representations
Authors: Deuar Piotr
Published: May 2021

A number of physically intuitive results for the calculation of multi-time correlations in phase-space representations of quantum mechanics are obtained. They relate time-dependent stochastic samples to multi-time observables, and rely on the presence of derivative-free operator identities. In particular, expressions for time-ordered normal-ordered observables in the positive-P distribution are derived which replace Heisenberg operators with the bare time-dependent stochastic variables, confirming extension of earlier such results for the Glauber-Sudarshan P. Analogous expressions are found for the anti-normal-ordered case of the doubled phase-space Q representation, along with conversion rules among doubled phase-space s-ordered representations. The latter are then shown to be readily exploited to further calculate anti-normal and mixed-ordered multi-time observables in the positive-P, Wigner, and doubled-Wigner representations. Which mixed-order observables are amenable and which are not is indicated, and explicit tallies are given up to 4th order. Overall, the theory of quantum multi-time observables in phase-space representations is extended, allowing non-perturbative treatment of many cases. The accuracy, usability, and scalability of the results to large systems is demonstrated using stochastic simulations of the unconventional photon blockade system and a related Bose-Hubbard chain. In addition, a robust but simple algorithm for integration of stochastic equations for phase-space samples is provided.
O jogo dos falsos tronos: do arquétipo nobre ao estereótipo esnobe
Authors: De Melo Lucas Almeida , De Paula Marcus Vinicius
Published: May 2021

Trata-se de uma investigação intermidiática que utiliza a teoria iconológica de William Mitchell (1995) para associar as características gráficas e conceituais de um jogo contemporâneo a uma ideologia esnobe e historicista – encontrada em pinturas, romances e folhetins, no século XIX – com o intuito de produzir uma reflexão sobre o consumismo. Questionam-se os fundamentos de uma cultura visual e verbal difusora da necessidade de se adquirir uma identidade aristocrática clichê mascarada por pretensões arquetípicas. O objetivo é entender em que medida esse modelo, aparentemente arcaico, distante e inócuo, pode ainda reverberar na comunicação visual veiculada numa mídia moderna.
O visível e o invisível da imagem em Bavcar
Authors: Dos Santos Sérgio Coutinho , Kabengele Daniela do Carmo , Mendes Júnior Walcler de Lima , Monteiro Lorenna Nascimento
Published: May 2021

Esta análise propõe desenvolver o conceito de imagem que apela à problematização dos campos do visível e do invisível. Através da obra do fotógrafo Evgen Bavcar, discute-se as possibilidades de expressão e relação entre imagens e coisas que se apontam no mundo, para além da mera ideia de representação ou de um suposto real que existiria como materialidade pura. O texto segue destacando as intrínsecas possibilidades de relacionamento entre a palavra e a imagem e como abrem-se territórios de acolhimento e troca entre percepções de deficientes visuais e percepções oculocêntricas. Trata-se de propor um tipo de troca, expresso por uma pós-imagem, em que a deficiência visual seja percebida como possibilidade de abertura para outras leituras de mundo, outras sensibilidades e percepções. Abre-se um modo de inserção do deficiente visual, por trocas entre percepções do visível e do invisível.
Educación remota y acceso tecnológico en Paraguay: perspectiva de padres y alumnos a través del COVID-19
Authors: Canese Valentina , Mereles Juan Ignacio , Amarilla Jessica
Published: May 2021

Las medidas adoptadas como resultado de la pandemia de COVID-19 han hecho que más del 70 % de las instituciones educativas de todo el mundo se cierren e implementen estrategias para dar continuidad a los procesos educativos escolares. En este estudio se analizan las perspectivas de los padres y los estudiantes con respecto a los retos y dificultades relacionados con el acceso a los recursos tecnológicos y la realización de actividades educativas en el Paraguay. Se utilizó una metodología mixta, cuantitativa y cualitativa; se administraron cuestionarios cerrados y abiertos durante las primeras semanas de cuarentena. La muestra incluyó 505 padres y 856 estudiantes de instituciones públicas y privadas de todo el país. Se encontraron diferencias significativas en el acceso a dispositivos como teléfonos móviles y computadoras (p< 0,001), pero no en las limitaciones para conectarse a internet (p= 0,58). Los participantes coinciden en que las principales dificultades incluyen la falta de comprensión de las tareas asignadas, la falta de motivación y problemas de conectividad, especialmente en el interior del país. Llegar correctamente a padres y estudiantes es de vital importancia si se quiere asegurar la calidad de la educación y la continuidad del proceso educativo.
Dimensión ética de la actividad científica y tecnológica en Latinoamérica. Una visión de Ciencia, Tecnología y Sociedad
Authors: Fernández-Bermúdez Adianez , Rodríguez-Ramírez Daily
Published: May 2021

El desarrollo de la actividad científica y tecnológica por intelectuales y científicos en América Latina, durante las décadas del 60 y 70 del siglo XX, puso en evidencia la explicación de nuevos valores epistémicos y prácticos que la conforman, por lo que valorar la dimensión ética de esta actividad constituye el objetivo principal de este estudio. Para ello se utilizaron los métodos generales del conocimiento propios del nivel teórico y los estudios sobre el pensamiento social además del análisis documental como técnica de investigación a través del análisis de contenido latente. La valoración del uso eficaz de la ciencia y la tecnología para revertir las tendencias negativas y la utilización de este material en los estudios de postgrado, son elementos que representan la aplicación práctica del tema. Su originalidad radica en la valoración de la comprensión ética como uno de los ejes articuladores del enfoque social de la ciencia y la tecnología en el contexto latinoamericano. En el estudio se refleja el vínculo entre la dimensión ética, la ciencia y la tecnología en cada una de las proyecciones de los principales autores abordados, tomando como referencia una ética subyacente a partir de principios como la responsabilidad, la transparencia y el compromiso social.
The Practice Is the Curriculum
Authors: Neutze Dana , Hodge Bryan , Steinbacher Erika , Carter Charles , Donahue Katrina E. , Carek Peter J.
Published: May 2021

abstract: The training family medicine residents receive will have a lasting impact on how they deliver care in the future. Evidence demonstrates an imprinting effect based on the training environment itself. Thus, residency training represents a critical time for establishing clinical experiences that embody core primary care principles and ensure excellent care delivery. This paper focuses on the clinical experience in the family medicine practice setting. We have used Starfield’s four C’s of primary care and added two more: cost and community, as the tools to achieve the triple aim. In reviewing the current state of residency programs across the country, we noted that there was a lack of measurement on how programs were performing when it came to the six C’s. We will briefly describe some recent innovative collaboratives among residencies. Next, we examine the six C’s of primary care in context of current care. These six C’s inform our recommendations for residency training standards to create the family physicians of the future. The overarching theme of these recommendations is the need to measure and report on what we want to ultimately improve.
Apuração in loco: o impacto do trabalho de campo no fazer jornalístico
Authors: Rovida Mara
Published: May 2021

Numa sociedade orientada pela tecnologia, o investimento no trabalho de campo como elemento essencial da apuração jornalística parece cada vez mais raro. Na contramão dessa realidade, observa-se o trabalho in loco como diferencial na elaboração de narrativas sobre temas do cotidiano urbano. A relação entre dialogia jornalística e observação-experiência no exemplo da cobertura radiofônica do trânsito é discutida neste artigo. A costura de vozes e perspectivas de personagens do trânsito urbano é observada em seu aspecto dialógico nas narrativas da Radio Trânsito (antiga SulAmérica Trânsito). A metodologia de trabalho que dá base para o presente debate está alicerçada na pesquisa empírica cujos sujeitos observados são os jornalistas que atuam na emissora de rádio escolhida para esta análise.
Circunlóquio da Palavra
Authors: Chauvin Jean Pierre
Published: May 2021

Neste ensaio, propõe-se acercar-se da Palavra, considerando algumas de suas variadas acepções. Recorrendo a reflexões de Roland Barthes e Michel Foucault, discutem-se circunstâncias que envolvem a concepção de mundo e sua representação, tanto na literatura quanto no discurso cotidiano.
Narrativa e temporalidade na cultura midiática
Authors: Follain Vera
Published: May 2021

Distanciando-se das abordagens formalistas, o artigo constitui-se numa reflexão sobre o lugar da narrativa na cultura midiática, considerando a problematização da instância da enunciação, do próprio ato de narrar, intensificada ao longo do século XX. Por esse viés, discute-se o abalo da hegemonia da narrativa como forma de estruturar nossa experiência do tempo, tendo em vista o avanço da tecnologia digital e a crescente afirmação de uma cultura do banco de dados.
botinha branca e a echarpe verde
Authors: Bon Velozo Olga Pontes , Siciliano Tatiana
Published: May 2021

O artigo se propõe a compreender o sentido dado à objetos dos mais diversos dentro de perspectivas e estudos que abarcam o fenômeno do consumo, ao entender que estes mesmos objetos passam a estetizar a vida cotidiana, a partir de sistemas classificatórios e simbologias sobrepostas em nossa sociedade contemporânea. Deste modo, nos encontramos, diariamente, atravessados pelo sistema de consumo e suas narrativas complexas, onde bens materiais são transformados em totens mágicos e poder simbólico. Neste contexto, o trabalho fará uso de autores como Jean Baudrillard para refletir sobre as relações construídas entre pessoas e objetos, a partir de um prosaico relato adolescente: a compra de uma bota branca; e de uma cena específica do filme Os delírios de consumo de Becky Bloom: a compra de uma echarpe verde.