bluuebunny/crossref_metadata_2025 huggingface dataset:
Considerations for the Integration of Glass in Superyacht Structures
Authors: Wium Daniël , Lataire Evert , Belis Jan
Published: June 2022

In recent years, it has become popular for superyacht designs to incorporate large uninterrupted glazed areas in the superstructure. Larger windows increase the amount of natural light that enters the yacht and add to the yacht’s aesthetic appeal and exclusivity. Cruise vessels and other types of passenger ships have seen similar trends. However, window panes are currently isolated from the structural loads within a vessel and their dimensions are restricted by the presence of a frame as a conventional load-bearing structural component. The use of load-bearing glass components presents a solution to this problem as it can also add to the strength of a ship’s structure, thereby reducing the extent of conventional structural materials such as steel or aluminium profiles. Major challenges exist for the use of glass as a load bearing component in a ships’ structure. Even though a solid scientific background has been established for the structural use of glass in structures on land, a lack in knowledge exists of how the challenges in the marine environment can be addressed. This paper gives an overview of the requirements of a ship structure, and more specifically yacht structures, and describes the challenges associated with using glass as a fully integrated structural component. Further implications for the integration of structural glass in a superyacht structure are also discussed and suggestions for a possible design approach is presented.
Investigation the Effect of Boric Acid effect on Antioxidant System, HDL Levels and PON Activity on Rats Feding to the High-Fat Diet
Authors: KALAÇAY Destan , ATAKİSİ Onur
Published: June 2022

Recent studies have revealed that boron compounds can be effective in the treatment of obesity, which is known to be one of the most dangerous and complex health problems of this age. In this study, the therapeutic effect of boron molecules in the diet on obesity was investigated.

For this purpose, the effects of boron compounds on Total Antioxidant Status (TAS), Total Oxidant Status (TOS), High Density Lipoprotein (HDL) levels and paraoxanase (PON) activity were investigated in mice fed a high-fat diet.

The study material was 40 Sprague Dawley rats 4-5 months old with a mean live weight of 226.95 ± 5.75 g. Animals were divided into 4 groups as Group I (normal diet), Group II (High fat), Group III (High fat + Boric Acid) and Group IV (Boric Acid). Six weeks after the experiment, blood samples were taken from the animals and TAS, TOS, HDL levels and PON activity were measured from the samples. In addition, the live weight changes of the animals were recorded.

At the end of the study, we found that boric acid given in addition to drinking water did not significantly change TAS level and PON activity, but increased TOS and HDL levels. In addition, the weight average of the group treated with boric acid decreased.

As a result, boric acid did not have an effect on the antioxidant system, but it caused an increase in HDL level and a decrease in PON activity. In addition, boric acid can be effective in lowering body weight.
Formulation and Evaluation of Herbal Toothpowder
Authors: Miss. Pratiksha N. Uchale  , Dr. Subhash T. Kumbhar
Published: June 2022

Denitrifies are the product which is used to maintain the oral hygiene such as freshness of mouth and to avoid tooth decay The oral hygiene can be maintained throughout the day by using various Dentrifices prepared by herbal and synthetic ingredients. This work was carried out to prepare a tooth powder which can be used as a tool for proper oral hygiene and to overcome the side effects of the conventional tooth powder which can be used as a tool for proper oral hygiene and to overcome the side effects of the conventional tooth powder prepared by synthetic ingredients. Tooth powder is used in combination with tooth brush to maintain the oral hygiene such as freshness of mouth and to avoid tooth decay. The work was carried out to prepare a tooth powder which can be used as a tool for proper oral hygiene and to overcome the side effects of the conventional tooth powder prepared by synthetic ingredients. The tooth powder was prepared by using various herbal ingredients which posses the antibacterial, antiseptic and cooling properties. The prepared tooth powder way evaluated for its organoleptic and physical characteristic such as color, odor, taste, stability, pH , moisture content, swelling index flow property, bulk density, tapped density and abrasiveness to ensure that it posses all the desired futures to use against the dental diseases. The result was found to be within the permitted limits.
The Opportunity for Occupational Therapy in Pediatric Disaster Recovery
Authors: Rashad Diamond E. , Zapf Susan A. , Groger Sandra E.
Published: June 2022

As natural disasters increase in frequency throughout the world, more children and families are exposed to disaster-related stress and trauma. Many children with disaster exposure face occupational disruption, in which common activities, roles, and relationships are damaged or destroyed. In this descriptive column, we explore the impact that natural disasters have on children, the contribution of pediatric occupational therapy to disaster management, and the opportunity for occupational therapy practitioners to engage in collaborative psychosocial and activity interventions during disaster recovery. Through trauma-informed occupational therapy, children in traditional and community-based services will benefit from assistance in restoring normalcy. With this column, we aim to contribute to the continued exploration of roles in pediatric disaster prevention and recovery and a call for qualitative and quantitative scholarship in this setting.
The role of mobile applications in the conservative management of stress urinary incontinence in women
Authors: Pilch Anna , Magdoń-Kierzkowska Gabriela
Published: June 2022

Urinary incontinence (UI) affecting over 300 million women worldwide, regardless of race and age, is considered one of the most important health issues in the 21st century. Due to the scale of the problem, the priority should be to provide therapy to as many patients as possible. Although effective conservative treatment measures for UI are available, they may not cater to all individuals who seek help. Sometimes a sense of embarrassment or a fear of stigmatization causes patients’ reluctance to report UI symptoms to their health provider and to join therapy. That forces to search for the new approach. In this field, use of mHealth technologies seems very promising. They became even more valuable during the Covid-19 pandemic, when the interest in telemedicine, as a means of providing care, while not being exposed to the risk of virus infection, further increased.

The purpose of this work is a narrative review showing possibilities of using conservative measures of stress urinary incontinence (SUI) in women, with particular emphasis on the use of mHealth technologies, as recent studies have shown that mobile application seem to be an effective tool in terms of improving SUI symptoms, satisfaction and adherence to therapy.
MALÁRIA UMA PARASITEMIA EM DECLÍNIO: UMA VISÃO DO QUADRO EPIDEMIOLÓGICO DA MALÁRIA NO BRASIL NOS ÚLTIMOS ANOS DE 2019 A 2021
Authors: Russo Felipo Giovani Feitosa , Souza Fênix Rafaiela Ferman
Published: June 2022

Introdução: A malária e uma doença infecto parasitaria, com um elevado gral de distribuição no mundo espalhando-se por América, África, Ásia e Oceania, continentes estes que abrigam quase a metade da população mundial. Já nas Américas a malária tem ocorrência na América do Sul, central e caribe (Brasil, Bolívia, Colômbia, equador, El Salvador, Haiti Honduras, Peru e Venezuela). Dados da Organização Mundial Da Saúde os países que mais ocorreram casos de infecção por malária na América do Sul são Brasil, Colômbia e Venezuela. Objetivo: Neste resumo buscou-se avaliar o número de casos oficiais registrados no Brasil e os cinco estados que mais contribuíram para estes números no período de janeiro a junho de 2019, 2020 e 2021. Metodologia: Foram utilizados os seguintes parâmetros de busca: a) definição do tema (perfil epidemiológico nos 5 estados que mais ocorrem malária no Brasil): b) escolha das palavras chaves (boletim, epidemiológico, malária, ministério da saúde); c) período de publicação (2019 a 2021); d) identificação dos resultados. Resultados: A busca apontou 1780 Resultados neste período no período de 2019 a 2021, no entanto, foram aproveitados somente dados oficiais do Ministério da Saúde (MS). Sendo observados de janeiro a junho de 2019 no Brasil notificou 70.264 casos de malária na região amazônica sendo os estados que mais contribuíram para estes números foram o Amazonas (29.615), Pará (15.346), Roraima (9.704), Acre (6.500) e Amapá (4.670), casos notificados. No mesmo período do ano de 2020 o Brasil registrou 65.558 mil casos na Amazônia os estados do Amazonas (28.051), Roraima (13.466), Pará (9.832), Acre (5.548) e Rondônia (4.860), faram os que mais contribuíram neste período para este número. Já no ano de 2021 na mesma temporada de janeiro a junho do ano de foram registrados 57.374 mil acometidos por malária, sendo os estados do Amazonas (23.667), Roraima (12.199), Pará (8.109), Rondônia (5.596) e Acre (4.051). Conclusão: Observa-se que está havendo um decaimento no número de casos acometidos por malária em grande maioria dos estados apenas em Rondônia houve aumento de caos, demostrando que o plano brasileiro de contingência da malária está alcançando seu objetivo.
Regulación pública en turismo
Authors:   Universidad Nacional de San Martín, Córdova Calle Elia Anacely , Flores Ramírez Rony ,   Universidad Nacional de San Martín, López Sánchez Teresa del Pilar ,   Universidad Nacional de San Martín
Published: June 2022

Este libro se presenta con la intención de explicar de qué se trata la regulación pública de los servicios públicos en el Perú, en donde el Estado, como regulador de la vida económica, es necesario, y cómo se conjuga éste con la actividad turística, en primer lugar, porque todas las relaciones humanas precisan de normas y leyes de comportamiento, y, en segundo lugar, por razones económicas que justifican esa intervención pública. En este marco, se presenta una serie de casos para establecer mecanismos de reflexión para poder realizar un buen trabajo y desempeño en todas las instituciones que forman parte de la cadena de valor del turismo y la economía, siendo útil como un instrumento guía para docentes, estudiantes, empresarios y servidores públicos implicados en que emerja sosteniblemente esta importante labor. Además, se adjunta modelos y fichas de evaluaciones que utilizan algunas instituciones como MINCETUR, CENFOTUR, entre otras, para el diagnóstico de empresas turísticas, que nos pueden servir como modelos de regulación pública y privada, con el único propósito de ayudar a cualquier profesional en el ejercicio de sus funciones. Además de otros ejemplos y conceptos de la regulación económica en beneficio de todo el país.
Erciyes Clinical Guideline For Multisystem Inflammatory Syndrome In Children (MIS-C) Associated With COVID-19
Authors: Cetin Benhur Sirvan , Kısaarslan Ayşenur Paç , Baykan Ali , Akyıldız Başak Nur , Poyrazoglu Hakan
Published: June 2022

Multisystem Inflammatory Syndrome in Children (MIS-C) is an inflammatory response to prior SARS-CoV-2 infection. Clinical features of MIS-C could resemble those seen in other diseases, including Kawasaki Disease, Hemophagocytic Lymphohistiocytosis, and cardiovascular shock. The pathogenesis is unclear; however, it is thought to develop 4 to 6 weeks after infection. This guideline aims to provide a framework for physicians to use to guide the evaluation of patients and management of those diagnosed with MIS-C.
Demographic features of patients followed up in COVID intensive care units during the pandemic period
Authors: İncaman Deniz , Çolak Rumeysa , Çınar Mahmut , Çalışır Abdullah İbrahim
Published: June 2022

Aim: Coronavirus disease is the third coronavirus infection defined in the world in the 21st century, after severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS).Material and Method: We planned to evaluate demographic characteristics retrospectively and present them to the literature with statistical data. The patients included in our study, positive PCR ( polymerase chain reaction) test, who is under treatment in the COVID-19 intensive care units of our hospital due to COVID-19 disease. Age, comorbid conditions, admission complaints, physical examination findings, acute phase reactants, tomography results, length of hospital stay, and treatments of these patients were scanned from the patient files.Results: Demographic characteristics were found to be similar to the literature, but there is not enough data in the literature about chronic drug use. Elderly age, cardiovascular diseases, and ıntensive care unit hospitalization were associated with mortality.Conclusion: The patient group who has a chronic disease and uses multiple drugs should be considered. We think that we contribute to the literature with this information in our study.
The effect of intraoperative epidural levobupivacaine administration in lumbar disc surgery for postoperative pain
Authors: Çetin Gül Serpil , Yılmaz Ayşe , Balaban Zeynep , Yılmaz Özgür , Yörükoğlu Dilek
Published: June 2022

Aim: Postoperative pain is an essential problem that affects morbidity in surgical cases. We aimed to provide maximal benefits with minimal side effects, facilitate the recovery period, accelerate mobilization, and provide patient safety and comfort through the usage of the drug and method of our choice to provide postoperative analgesia.Material and Method: Our study included 60 elective or urgent lumbar disc surgery cases. The patients were randomly divided into two groups; (a) The Group S; patients receiving general anesthesia and intraoperative epidural saline injection, and (b) The Group L; patients receiving general anesthesia and intraoperative epidural 2.5 mg/mL levobupivacaine 10 mL injection. The patient’s hemodynamic parameters were monitored perioperatively. To all patients, in case of necessity, patient-controlled analgesia with IV morphine was administered. The pain assessment was done using a numeric pain rating scale and visual analog scale. In addition, morphine usage during the 24 hours, pain scores, mobilization time, patient satisfaction, and side effects were evaluated.Results: In the levobupivacaine group, the pain scores were lower during the whole trial, the morphine consumption in the 24 hour period was lower, the first time of mobilization was shorter, the patient satisfaction was more remarkable, and this group was more clinically significant considering side effects.Conclusion: The usage of epidural bupivacaine combined with IV morphine instead of IV morphine alone for postoperative analgesia is more beneficial for early mobilization, reducing complications, and better patient satisfaction
Calcinosis cutis in the auricle: a case report
Authors: Atalay Fatma , Topal Kübra , Kars Ayhan
Published: June 2022

Calcinosis cutis is a rare condition defined as the pathological accumulation of amorphous insoluble calcium salts in cutaneous and subcutaneous tissue. There are four subtypes - dystrophic, idiopathic, metastatic, and iatrogenic calcification. The dystrophic form is the most common type of calcinosis cutis, the major agent being trauma. Serum calcium and phosphorus values are within normal limits in these patients. The clinical manifestation generally involves small white papules, and subcutaneous nodules or plaques. The first choice in the treatment of calcinosis cutis is surgery. Surgical procedures have been recommended as the first and most effective option in almost all cases in the literature. We report a case of a patient presenting with growing, painless swelling following trauma to the auricle of the ear identified as dystrophic calcinosis cutis following surgical excision.
RỐI LOẠN ĐÔNG MÁU Ở TRẺ SỐC SỐT XUẤT HUYẾT DENGUE
Authors: Nguyễn Thế Nguyên Phùng , Quý Tỷ Dao Nguyễn , Diệp Tuấn Trần
Published: June 2022

Đặt vấn đề- Mục tiêu: rối loạn đông máu là 1 trong 2 cơ chế bệnh sinh của sốt xuất huyết dengue. Nghiên cứu này khảo sát tình trạng rối loạn đông máu ở bệnh nhi sốc sốt xuất huyết dengue tại Khoa Hồi Sức Tích Cực Chống Độc Bệnh Viện Nhi Đồng 1. Đối tượng và phương pháp: Nghiên cứu 466 trẻ chẩn đoán sốc sốc sốt xuất huyết dengue nhập Bệnh Viện Nhi Đồng 1 từ ngày 1 tháng 12 năm 2017 đến ngày 30 tháng 6 năm 2019. Đông máu được thực hiện tại các thời điểm lúc sốc (T0), 24 giờ (T24) và 48 giờ (T48) sau thời điểm sốc. Kết quả: Tuổi trung bình 9,4 ± 3,1 tuổi, trong đó 251 (53,9%) trẻ nam. 4,7% có biểu hiện xuất huyết trên lâm sàng, trong đó xuất huyết tiêu hoá là 7 ca (1,5%), chảy máu mũi 7 ca (1,5%), chảy máu chân răng 2 ca (0,4%), hành kinh kéo dài 6 ca (1,3%). Trong quá trình điều trị chảy máu tiêu hoá thêm 5 ca, trong đó tổng số ca xuất huyết tiêu hoá nặng cần truyền máu là 6 ca (1,3%). Giá trị trung bình số lượng tiểu cầu (đơn vị x103/mm3) các thời điểm T0, 24, 48 lần lượt là 38,9 ± 24,1 ; 27,3 ± 24,1 ; 36 ± 27. Tỷ lệ phần trăm giảm tiểu cầu tại thời điểm T0, 24, 48 lần lượt là: 84,3% ; 97,8% và 100%. Tỷ lệ APTT kéo dài thời điểm T0, 24, 48 lần lượt là 25,4% ; 78,3% và 66,7%. Tỷ lệ kéo dài PT thời điểm T0, 24, 48 lần lượt là 4,4%; 39,1% và 44%. Tỷ lệ giảm fibrinogen < 1 g/l thời điểm T0, 24, 48 lần lượt là 3%; 54,9% và 32%. Ở thời điểm nhập viện: rối loạn đông máu có 70 (25,9%), trong đó 6 trường hợp (2,2%) thoả tiêu chuẩn DIC. Trong 48 giờ theo dõi rối loạn đông máu 140 (40,8%) và DIC là 39 trường hợp (11,4%). Tỷ lệ trẻ cần truyền các chế phẩm hồng cầu lắng, tiểu cầu, huyết tương tươi đông lạnh, kết tủa lạnh lần lượt là 3,2%; 3,6%; 2,4% và 3,2%. Kết luận: Rối loạn đông máu có tỷ lệ 40,8% trong sốc SXHD ở trẻ em, trong đó DIC là 11,4%. Biểu hiện lâm sàng nặng có tỷ lệ thấp. Tỷ lệ trẻ cần truyền các chế phẩm thấp và rối loạn đông hồi phục với điều trị và diễn tiến của bệnh.
SỬ DỤNG DỊCH VỤ Y HỌC CỔ TRUYỀN CỦA NGƯỜI DÂN TẠI TRẠM Y TẾ PHƯỜNG 9, QUẬN 8, THÀNH PHỐ HỒ CHÍ MINH
Authors: Thị Kim Anh Võ , Hồng Chương Nguyễn , Thị Mỹ Trang Nguyễn , Phú Nguyên Hưng Lê
Published: June 2022

Mục tiêu: Mô tả thực trạng sử dụng y học cổ truyền của người dân tại trạm y tế phường 9, quận 8, thành phố Hồ Chí Minh. Phương pháp: Nghiên cứu cắt ngang mô tả trên 347 người dân đến khám tại trạm y tế phường 9 từ tháng 12/2018 đến tháng 4/2019, hình thức phỏng vấn trực tiếp bằng bộ câu hỏi cấu trúc soạn sẵn. Kết quả: Tỷ lệ người dân sử dụng y học cổ truyền tại trạm y tế là 70,6%. Lý do chủ yếu được chọn sử dụng là gần nhà 87,3% và chi phí thấp 84,1%. Hình thức sử dụng chủ yếu là kết hợp giữa thuốc y học cổ truyền và xoa bóp, bấm huyệt chiếm 71%. Các yếu tố thực sự có tác động mạnh đến tỷ lệ sử dụng dịch vụ y học cổ truyền bao gồm: biết chữa bệnh bằng y học cổ truyền, được nhân viên y tế hướng dẫn sử dụng dịch vụ và trạm y tế đáp ứng tốt việc khám chữa bệnh.
NGHIÊN CỨU THỰC TRẠNG TUÂN THỦ SỬ DỤNG THUỐC VÀ SO SÁNH MỘT SỐ YẾU TỐ ẢNH HƯỞNG ĐẾN TUÂN THỦ SỬ DỤNG THUỐC Ở NGƯỜI BỆNH ĐÁI THÁO ĐƯỜNG TÍP 2 TẠI BỆNH VIỆN ĐẠI HỌC Y HÀ NỘI
Authors: Thu Thuỷ Lê , Thị Hiên Lương , Quang Tuyến Hà , Thị Song Hà Nguyễn
Published: June 2022

Mục tiêu: Mô tả thực trạng tuân thủ sử dụng thuốc và một số yếu tố ảnh hưởng đến tuân thủ sử dụng thuốc ở người bệnh đái tháo đường (ĐTĐ) típ 2 tại bệnh viện Đại học Y Hà Nội. Phương pháp nghiên cứu: Nghiên cứu mô tả cắt ngang sử dụng 2 phương pháp thu thập dữ liệu là phỏng vấn qua điện thoại bằng bộ câu hỏi và hồi cứu dữ liệu trên hệ thống phần mềm của bệnh viện. Sử dụng phần mềm R để thực hiện các phân tích mô tả. Kết quả: 79,3% người bệnh tham gia nghiên cứu tuân thủ sử dụng thuốc. Điểm trung bình tuân thủ sử dụng thuốc là 6,87 (SD=1,41). Một số yếu tố được xem xét ảnh hưởng đến việc không tuân thủ sử dụng thuốc là yếu tố nhân khẩu học, quản lý bệnh, bệnh, kiến thức về thuốc điều trị và thái độ. Bốn yếu tố khác biệt có ý nghĩa thống kê giữa nhóm tuân thủ và không tuân thủ sử dụng thuốc là tiền sử gia đình có người mắc bệnh ĐTĐ, đi khám đều đặn, lo sợ gặp tác dụng phụ của thuốc và lo sợ gặp biến chứng của bệnh. Kết luận: Người bệnh tham gia nghiên cứu tuân thủ tương đối tốt tuân thủ sử dụng thuốc và có một số yếu tố có sự khác biệt giữa nhóm tuân thủ và không tuân thủ.
THỰC TRẠNG KÊ ĐƠN THUỐC ĐIỀU TRỊ TĂNG HUYẾT ÁP TRONG ĐIỀU TRỊ NGOẠI TRÚ TẠI BVTW QUÂN ĐỘI 108 NĂM 2019
Authors: Thị Lan Anh Trần , Đức Anh Mai , Thị Thu Hằng Lê
Published: June 2022

Đặt vấn đề: Hiện nay, tăng huyết áp (THA) là một trong những bệnh mạn tính được thăm khám chủ yếu trong điều trị ngoại trú tại các bệnh viện đa khoa ở nước ta. Kê đơn thuốc ngoại trú phù hợp về phác đồ và liều dùng sẽ góp phần đáng kể giúp người bệnh kiểm soát huyết áp tốt và giảm tình trạng nhập viện. Nghiên cứu được thực hiện nhằm mục đích phân tích các liệu pháp kê đơn và liều sử dụng trong điều trị ngoại trú bệnh THA tại bệnh viện. Đối tượng và phương pháp nghiên cứu: Đơn thuốc điều trị ngoại trú được chẩn đoán bệnh tăng huyết áp lưu tại khoa Dược bệnh viện TWQĐ 108, phương pháp nghiên cứu mô tả cắt ngang. Kết quả: Liệu pháp đa trị liệu là liệu pháp có tỷ lệ điều trị cao nhất (78%) trong tổng số các liệu pháp điều trị và có chi phí trung bình cho một đơn thuốc cao nhất: 364.688 đồng. Đơn thuốc được kê kết hợp 3 nhóm ARB + BB + CCB có tỷ lệ số đơn nhiều nhất, tương ứng 10,05%. Thuốc ramipril là thuốc được kê đơn trị liệu cao nhất. Các nhóm thuốc CCB và ARB có liều PDD/DDD gằn bằng 1, đúng với liều khuyến cáo trong khi nhóm ACE-I có liều kê đơn chưa phù hợp với khuyến cáo. Kết luận: Phần lớn các đơn thuốc trong mẫu nghiên cứu áp dụng kê đơn đa trị liệu. So sánh liều kê đơn với liều DDD có sự khác nhau giữa các nhóm thuốc.
Reasons Making Newly Baptized Members Relapse into Alcoholism
Authors: Tom Ogal; Jongimpi Papu; David Odhiambo; Robert Osei-Bonsu. Azaria O. Otula;
Published: June 2022

This study focused on determining why newly baptized members relapse into alcoholism. The study examines Biblical principles of mentoring and reviews related literature to develop a strategy for recovering alcohol addicts in the church. In addition, the study investigates the reasons why they relapse to drinking after baptism. To solve the problem, the researcher used a mixed research method, which is a combination of qualitative and quantitative methods. This involved digging into concepts, characteristics, symbols, and descriptions. This approach gave the researcher sufficient opportunity to delve into possible solutions to the research questions as to what reasons make newly baptized members to relapse into alcoholism. The mixed-method helped the researcher gain a more complete picture of the research than the stand-alone quantitative and qualitative methods. The addicts gave true reasons why they left the church after baptism, there is no special program for them after and before baptism, how the church members handle them was a problem to them, they also have their weaknesses, which come from the environment like the availability of alcohol, peer pressure, the unresolved issues and others. Since this problem is a global problem, there is a need to open Rehabilitation centres where the addicts can be nurtured after baptism or before they are baptized for the church to meet their needs through training them in the rehabilitation centres.
ORHAN PAMUK’UN “VEBA GECELERİ” ROMANINDA ÖLÜM KAYGISI
Authors: KARABULUT Mustafa , KARASU Ferhat
Published: June 2022

Ölüm kaygısı, insanoğlunun genel olarak en büyük kaygısıdır. Ölüm, insanın en büyük kaybıdır. Orhan Pamuk’un Veba Geceleri adlı romanında 1901 yılında Osmanlı Devleti’ne bağlı olan Minger Adası’ndaki veba salgını ile yapılan mücadele anlatılır. Romanın merkezinde veba salgını olmakla birlikte kimi zaman salgınla ilgili kimi zaman da salgından bağımsız aşk hikâyeleri, siyasi ilişkiler, polisiye olayları, Osmanlının son dönemine ilişkin tarihi analizler farklı bakış açılarıyla ele alınır. Başkimyager Bonkowski Paşa ile Vali Sami Paşa arasındaki anlaşmazlık, Osmanlının son dönemindeki sancılı süreç, hanedan içerisindeki hesaplaşmalar ve bir kadın olarak Pakize Sultan’ın duygu dünyası romanda göze çarpan önemli unsurlardır. Yazar, veba hastalığının belirtilerini, farelerden insanlara bulaşmasını, insandan insana bulaşma yollarını, hastalığın bulaştıktan sonraki belirtilerini, salgınla ilgili tedbirlerin alınmasını ve hastalığın insan psikolojisi üzerindeki etkilerini dile getirir. Vebanın ortaya çıkmasıyla adadaki huzur ortamı kaybolur ve insanlar ölüm kaygısı ile baş başa kalırlar. İnsanlardaki korkunun temel kaynağı vebadır. Vebaya yakalanan insana artık ölü gözüyle bakılır ve ölüm sırasının kimde olduğu endişesi derinden hissedilir. Vebanın bir tedavisinin olmaması, vebaya yakalanan herkesin bir süre sonra ölmesi Minger Adası’nda korkuyu en üst seviyeye çıkarır. Bu makalede amaç, Orhan Pamuk’un Veba Geceleri adlı romanındaki ölüm korkusu ve kaygısını ortaya koymaktır.
Utilization of online media as an emergency alternative for implementing community service activities during the COVID-19 pandemic
Authors: Slamet Riyadi  , Bunda Taqiyya Syahri Ramadona , Bahrul Ulum  , Zulham Effendi  , Lubis Arbonas
Published: June 2022

Community service activities are a routine agenda for every college in Indonesia. although constrained by the pandemic which limits the space for carrying out social activities in the community, it must still be carried out. One solution to overcome the limited space for movement is to carry out community service activities online. By utilizing various kinds of existing social media, community service activities can also run as effectively as activities that go directly to the field. On the one hand, there are indeed many obstacles when interacting with the public through social media, but on the other hand, there is an advantage that is no less important: a much more comprehensive range of locations. Community service activities has been held in Desa Manis, Desa Bangkolak II, Medan Area, Kambu, Desa Atu Kapur, Kadia, Kumpeh Jambi, Manokwari, for two weeks starting on April 19 to May 2, 2021. Starting from the problem of the lack of public interest in studying the Al-Qur'an and familiarizing the recitations of the Al-Qur'an. At this Community service activity, we raised the theme Ramadhan with Al-Qur'an. The Community service activities begin with a village observation process to explore the villages and see the village's potential, which will be the main target in implementing the Community service activities. The programs are designed sequentially starting with discussions between Community service activities groups and lecturers. And it was found that this Community service activities activity would be carried out in two ways, directly and online. The implementation of the Community service activities program is carried out in a balanced manner, starting with planning, implementation, and evaluation at the end of each program. The results achieved from the entire Community service activities program include increased interest in the recitation of the Qur'an for online Community service activities participants and village communities with the holding of recitation presence programs every day. In the social sector, the Islamic book and magazine spread program is one of the programs to introduce and educate rural communities in literacy. Then it was closed with a competition program to increase enthusiasm for Community service activities participants and the community and as an appreciation for their participation in the Community service activities program that we have implemented
Stereotactic Ablative Radiotherapy for the Treatment of Oligometastatic Cancer: A Clinical Review as Part of a Health Technology Assessment, Version 2.0
Authors: Tran Khai , Kumar Diksha , Kim Joanne , Gates Allison , Loewen Shaun , Rader Tamara , MacDougall Danielle , Ford Caitlyn
Published: June 2022

Oligometastatic cancer (cancer with a limited number of metastases) represents an intermediate state between cancer confined to a single location in the body and cancer that has metastasized — or spread — widely.

One treatment option, for which there is growing interest, is stereotactic ablative radiotherapy, also known as SABR.

SABR precisely delivers a high dose of radiation to ablate tumours at specific sites while minimizing the radiation dose to surrounding normal tissues.

SABR may be used independently or alongside other treatment options in the management of oligometastatic cancer.

This CADTH clinical review evaluated the evidence regarding the clinical effectiveness and safety of SABR with or without standard of care (SOC) for people with oligometastatic cancer and found the following:

SABR in addition to SOC may offer a benefit in terms of overall survival (OS) and progression-free survival (PFS).

The findings for the effectiveness of SABR alone compared with SOC were mixed and deemed inconclusive.

There are insufficient data related to adverse events (AEs) at the present time to draw conclusions regarding the safety of SABR relative to SOC alternatives.

This CADTH clinical review was maintained as a living systematic review for 1 year from January 2021 to January 2022. Updates were conducted every 3 months during that year to ensure the findings remained up-to-date as new evidence emerged. Please refer to the CADTH project page for all versions of the report and for the version history document, which outlines the results of each quarterly update.
Building Three-Dimensional Model for Manama City Center Kingdom of Bahrain
Authors: Belaid Mohamed Ait , Altureeki Nissreen
Published: June 2022

This research project explains how Three-Dimensional (3D) city models are important and developed all over the world, because it represent the Earth’s surface and give the people the chance to enjoy a virtual visit in cities. It also presents some Techniques used for generating 3D cities, how we used it, and the difficulties we faced. It also shows that The Kingdom of Bahrain started to develop itself and to follow the world in its progress. A mosaic of high resolution aerial photographs was used to reconstruct 3D building models with accurate details. First, we used stereo graphics to determine the rooftops, roads and trees in the 3D window and also we determined the centroid of the roofs. Second, after finishing all roofs we used the tool extrude for extruding the buildings to ground and we used the tool 3D construct to extrude the buildings from the centroid of the roof. So the main goal of this paper was to build 3Dimensional buildings for Manama capital as a case study using available techniques and datasets. The results show that there is many ways to create 3D buildings if the dataset and the software are available, but not all the ways show real 3D city. In the present research we were able to extrude 3D solid buildings with high quality and high accuracy for Manama Center because this work was huge and needed many interpreters or operators with plenty of time.
Eksistensi Tarekat Naqsyabandi Haqqani di Jakarta
Authors: Estuningtiyas Retna Dwi
Published: June 2022

Tasawwuf saat ini tidak lagi dianggap hal baru bahkan sudah menjadi tren di mana diikuti banyak orang dengan mengikuti tarekat. Salah satu tarekat yang berkembang dengan baik dan dianggap muktabar yaitu tarekat Naqsyabandi Haqqani, dan eksis di Jakarta dan sekitarnya, bahkan tarekat ini berkembang di seluruh dunia. Tarekat ini masuk Jakarta  pertama kali masuk ke Jakarta pada bulan April 1997 diperkenalkan oleh Syaikh Muhammad Hisham Kabbani. Tarekat Naqsyabandi Haqqani merupakan cabang baru dari Naqsyanandi yang bersanad pada Baha’ al-Din Naqsyabandi (w. 1389). Naqsyabandiyah Haqqani dinisbatkan kepada pendiri Yayasan Haqqaniyah yaitu Syaikh Muhammad Nadzim Adil al-Haqqani yang berpusat di Cyprus. Ajaran Tarekat Naqsybandi Haqqani adalah tentang cinta, di mana pelaksanaan zikir dan berkumpul dilakukan di zawiyah-zawiyah yang tersebar di banyak tempat di bawah naungan Yayasan Haqqani Indonesia.
Analisis Semiotika De Saussure pada syair pupujian sunda Eling Eling Umat
Authors: Perdana Kiki Esa
Published: June 2022

Judul penelitian ini adalah “analisis semiotika pada syair pupujian sunda eling-eling umat”. Syair pupujian eling-eling umat ini merupakan ciri khas pupujian yang muncul pada tempat ibadah yang mayoritas penduduk nya orang sunda, karena pupujian menggunakan Bahasa sunda.  Ajaran pupujian sunda ini merupakan salah satu ajaran aswaja yang diserap oleh pertumbuhan islam di nusantara. Tujuan penelitian ini adalah untuk mengetahui bagaimana dari umat islam di indonesia, terutama di daerah sunda, dalam mempertahankan ajaran keislaman yang mereka percayai dalam menyebarkan syiar melalui kebudayaan. Pengumpulan data dilakukan melalui wawancara, observasi dan studi pustaka. Sedangkan pengujian validitas data dalam penelitian ini menggunakan triangulasi data, data yang diperoleh disesuaikan atau dilakukan cek ulang dengan sumber data lainnya. Berdasarkan hasil penelitian, penulis menyimpulkan pendekatan beragama menggunakan kebudayaan local setempat, dinilai cukup efektip untuk meyebarkan pendidikan dasar islam di masyarakat.

 

The title of this research is "semiotic analysis of the Sundanese poetry of the eling-eling umat". This eloquent verse of praise for the people is a characteristic of the praise that appears in places of worship where the majority of the population is Sundanese, because the praise uses the Sundane language. This Sundanese praise teaching is one of the Aswaja teachings that were absorbed by the growth of Islam in the archipelago. The purpose of this study is to find out how the Muslims in Indonesia, especially in the Sundanese area, maintain the Islamic teachings. They believe in spreading wisdom through culture. Data was collected through interviews, observation, and literature study. While testing the validity of the data in this study using data triangulation, the data obtained was adjusted or rechecked with other data sources. Based on the results of the study, the authors conclude that a religious approach using local culture is considered effective enough to spread Islamic basic education in the community.
Using Aircraft Measurements to Characterize Subgrid-Scale Variability of Aerosol Properties Near the ARM Southern Great Plains Site
Authors: Fast Jerome D. , Bell David , Liu Jiumeng , Mei Fan , Saliba Georges , Shilling John E. , Suski Kaitlyn , Tomlinson Jason , Wang Jian , Zaveri Rahul , Zelenyuk Alla
Published: June 2022

Abstract. Complex distributions of aerosol properties evolve in space and time as a function of emissions, new particle formation, coagulation, condensational growth, chemical transformation, phase changes, turbulent mixing and transport, removal processes, and ambient meteorological conditions. The ability of chemical transport models to represent the multi-scale processes affecting the lifecycle of aerosols depends on their spatial resolution since aerosol properties are assumed to be constant within a grid cell. Subgrid-scale-dependent processes that affect aerosol populations could have a significant impact on the formation of particles, their growth to cloud condensation nuclei (CCN) sizes, aerosol-cloud interactions, dry deposition and rainout, and hence their burdens, lifetimes, and radiative forcing. To address this issue, we characterize subgrid-scale variability in terms of measured aerosol number, size, composition, and CCN concentrations made by repeated aircraft flight paths over the Atmospheric Radiation Measurement (ARM) program’s Southern Great Plains (SGP) site during the Holistic Interactions of Shallow Clouds, Aerosols and Land Ecosystem (HI-SCALE) campaign. Subgrid variability is quantified in terms of both normalized frequency distributions and percentage difference percentiles using grid spacings of 3, 9, 27, and 81 km that represent those typically used by cloud-system resolving models as well as the current and next generation climate models. Even though the SGP site is a rural location, surprisingly large horizontal gradients in aerosol properties were frequently observed. For example, 90 % of the 3, 9, and 27 km cell mean organic matter concentrations differed from the 81 km cell around the SGP site by as much as ~46 %, large spatial variability in aerosol number concentrations and size distributions were found during new particle formation events, and consequently 90 % of the 3, 9, and 27 km cell mean CCN number concentrations differed from the 81-km cell mean by as much as ~38 %. The spatial variability varied seasonally for some aerosol properties, with some having larger spatial variability during the spring and others having larger variability during the late summer. While measurements at a single surface site cannot reflect the surrounding variability of aerosol properties at a given time, aircraft measurements that are averaged within an 81-km cell were found to be similar to many, but not all, aerosol properties measured at the ground SGP site. This analysis suggests that it is reasonable to directly compare most ground SGP site aerosol measurements with coarse global climate model predictions. In addition, the variability quantified by the aircraft can be used as an uncertainty range when comparing the surface point measurements to model predictions that use coarse grid spacings.
The formation and composition of the Mount Everest plume in winter
Authors: Hindman Edward E. , Lindstrom Scott
Published: June 2022

Abstract. Mount Everest's summit pyramid is the highest obstacle on earth to
the wintertime jet-stream winds. Downwind, in its wake, a visible plume can
form. The meteorology and composition of the plume are unknown. Accordingly,
daily from 1 November 2020 through 31 March 2021 (151 d), we observed
real-time images from a geosynchronous meteorological satellite to identify
the days plumes formed. The corresponding surface and upper-air
meteorological data were collected. The massif was visible on 143 d
(95 %), plumes formed on 63 d (44 %) and lasted an average of 12 h. We used the upper-air data with a basic meteorological model to show
the plumes formed when sufficiently moist air was drawn into the wake. We
conclude the plumes were composed initially of either cloud droplets or ice
particles depending on the temperature. The plumes were not composed of
resuspended snow. One plume was observed to glaciate downwind. We estimated
snowfall from the plumes may be significant.
Updated estimation of forest biomass carbon pools in China, 1977–2018
Authors: Yang Chen , Shi Yue , Sun Wenjuan , Zhu Jiangling , Ji Chengjun , Feng Yuhao , Ma Suhui , Guo Zhaodi , Fang Jingyun
Published: June 2022

Abstract. China is one of the major forest countries in the world,
and the accurate estimation of its forest biomass carbon (C) pool is
critical for evaluating the country's C budget and ecosystem services of
forests. Although several studies have estimated China's forest biomass
using national forest inventory data, most of them were limited to the
period of 2004–2008. In this study, we extended our estimation to the most
recent period of 2014–2018. Using datasets of eight inventory periods from
1977 to 2018 and the continuous biomass expansion factor method, we
estimated that the total biomass C pool and average biomass C density in
Chinese forests increased from 4717 Tg C (1 Tg = 1012 g) in the
period of 1977–1981 to 7975 Tg C in the period of 2014–2018 and 38.2 Mg C ha−1 to 45.8 Mg C ha−1 (1 Mg = 106 g), respectively, with a
net increase of 3258 Tg C and an annual sink of 88.0 Tg C yr−1. Over
the most recent 10 years (2009–2018), the average national forest biomass C
density and C sink were 44.6 Mg C ha−1 and 154.8 Tg C yr−1,
respectively, much larger than those of 39.6 Mg C ha−1 and 63.3 Tg C yr−1 in the period 1977–2008. These pronounced increases were largely
attributed to afforestation practices, forest growth, and environmental
changes. Our results have documented the importance of ecological
restoration practices, provided an essential basis for assessing ecosystem
services, and helped to achieve China's C neutrality target.
Causes of the weak emergent constraint on climate sensitivity at the Last Glacial Maximum
Authors: Renoult Martin , Sagoo Navjit , Zhu Jiang , Mauritsen Thorsten
Published: June 2022

Abstract. The use of paleoclimates to constrain the equilibrium climate sensitivity (ECS) has seen a growing interest. In particular, the Last Glacial Maximum (LGM) and the mid-Pliocene Warm Period have been used in emergent constraint approaches using simulations from the Paleoclimate Modelling Intercomparison Project (PMIP). Despite lower uncertainties regarding geological proxy data for the LGM in comparison with the Pliocene, the robustness of the emergent constraint between LGM temperature and ECS is weaker at both global and regional scales. Here, we investigate the climate of the LGM in models through different PMIP generations, and how various factors contribute to the spread of the model ensemble. Certain factors have large impact on an emergent constraint, such as state-dependency in climate feedbacks or model-dependency on ice sheet forcing. Other factors, such as models being out of energetic balance and sea-surface temperature not responding below -1.8 °C in polar regions have a limited influence. We quantify some of the contributions and find that they mostly have extratropical origins. Contrary to what has previously been suggested, from a statistical point of view, the PMIP model generations do not differ substantially. Finally, we show that the lack of high or low ECS models in the ensembles critically limits the strength and reliability of the emergent constraints.
Deep Learning Approach Towards Precipitation Nowcasting: Evaluating Regional Extrapolation Capabilities
Authors: Beutler Tarek , Rudolph Annette , Goehring Daniel , Vercauteren Nikki
Published: June 2022

Abstract. Precipitation nowcasting refers to the prediction of precipitation intensity in a local region and in a short timeframe up to 6 hours. The evaluation of spatial and temporal information still challenges todays numerical weather prediction models. The increasing possibilities to store and evaluate data combined with the advancements in the developments of artificial intelligence algorithms make it natural to use these methods to improve precipitation nowcasting. In this work a Convolutional Long Short-Term Memory network (ConvLSTM) is applied to Radar data of the GermanWeather Service. The positive effectiveness of finetuning a network pretrained at a different location and for different precipitation intensity thresholds is demonstrated. Furthermore, in the framework of two case studies the skill scores for the different thresholds are shown for a prediction time up to 100 minutes. The results highlight promising regional extrapolation capabilities for such neural networks for precipitation nowcasting.
Seed traits and phylogeny explain plant’s geographic distributions
Authors: Chen Kai , Burgess Kevin S. , He Fangliang , Yang Xiang-Yun , Gao Lian-Ming , Li De-Zhu
Published: June 2022

Abstract. Understanding the mechanisms that shape the geographic distribution of plant species is a central theme of biogeography. Although seed mass, seed dispersal mode and phylogeny have long been suspected to affect species distribution, the link between the sources of variation of these attributes and their effects to the distribution of seed plants are poorly documented. This study aims to quantify the joint effects of key seed traits and phylogeny on species’ distribution. We collected seed mass and seed dispersal mode from 1,426 species of seed plants representing 501 genera of 122 families and used 4,138,851 specimens to model species distributional range size. Phylogenetic generalized least squares regression and variation partitioning were performed to estimate the effects of seed mass, seed dispersal mode and phylogeny on species distribution. We found that species distributional range size was significantly constrained by phylogeny. Seed mass and its intraspecific variation were also important in limiting species distribution, but their effects were different among species with different dispersal modes. Variation partitioning revealed that seed mass, seed mass variability, seed dispersal mode and phylogeny together explained 46.82 % of the variance in species range size. Although seed traits are not typically used to model the geographic distributions of seed plants, our study provides direct evidence showing seed mass, seed dispersal mode and phylogeny are important in explaining species geographic distribution. This finding underscores the necessity to include seed traits and the phylogenetic history of species in climate-based niche models for predicting the response of plant geographic distribution to climate change.
HOTRUNZ: an open-access 1 km resolution monthly 1910–2019 time series of interpolated temperature and rainfall grids with associated uncertainty for New Zealand
Authors: Etherington Thomas R. , Perry George L. W. , Wilmshurst Janet M.
Published: June 2022

Abstract. Long time series of temperature and rainfall grids are
fundamental to understanding how these environmental variables affect
environmental or ecological patterns and processes such as plant
distributions, plant and animal phenology, wildfires, and hydrology. Ideally
such temperature and rainfall grids are openly available and associated with
uncertainties so that data-quality issues are transparent to users. We
present a History of Open Temperature and Rainfall with Uncertainty in New
Zealand (HOTRUNZ) that uses climatological aided natural neighbour
interpolation to provide monthly 1 km resolution grids of total rainfall,
mean air temperature, mean daily maximum air temperature, and mean daily
minimum air temperature across New Zealand from 1910 to 2019. HOTRUNZ
matches the best available temporal extent and spatial resolution of any
open-access temperature and rainfall grids that include New Zealand and is
unique in providing associated spatial uncertainty in the variables' units.
The HOTRUNZ grids capture the dynamic spatial and temporal nature of
monthly temperature and rainfall and the uncertainties associated with the
interpolation. We also demonstrate how to quantify and visualise temporal
trends across New Zealand that recognise the temporal and spatial variation
in uncertainties in the HOTRUNZ data. The HOTRUNZ data are openly available
at https://doi.org/10.7931/zmvz-xf30 (Etherington et al., 2021).