bluuebunny/crossref_metadata_2025 huggingface dataset:
Prevalence of Body Dysmorphic Disorder among Female Patients Seeking Cosmetic Procedures
Authors: Almuhanna N. , F. Abehed Abdullah, , Zainalabedin A. , Algaidi M. , Algamdi W.
Published: May 2022

Background: Body dysmorphic disorder (BDD) is a psychiatric illness in which one’s with minimal or non-existing defect in appearance shows significant distress and impairment in behavior and psychosocial functioning. Patients with body dysmorphic disorder seeking cosmetic surgery are usually unsatisfied with the outcomes of the surgery; this is why it is an important subject to be focused on. Moreover, physicians should consider the assessment of body dysmorphic disorder before undergoing any cosmetic procedures. Objective: To assess Body Dysmorphic Disorder in patients undergoing cosmetic procedures, and to improve the awareness of Body Dysmorphic Disorder among the providers of cosmetic treatment. Methods: This is a cross sectional study design, using the scale of body dysmorphic disorder modification of the Y-BOCS (BDD-YBOCS) adult version, consisting of 12 items regarding preoccupied thoughts of the participants and the effect on their lives. This scale individual respond to the light of the 5-point Likert-Type scale. We received 220 sample after distributing the questionnaire in different online platforms among females living in the eastern province of Saudi Arabia. Results: A total of 220 females participated in this cross-sectional study, 45 of them had Body Dysmorphic Disorder (prevalence rate of 20.5%) which shows a significant worrying percentage. Moreover, the results indicate that Body Dysmorphic Disorder is more among participants in the (20-35) year’s old age group. Furthermore, it shows a positive correlation between Body Dysmorphic Disorder and females seeking cosmetic procedures. Conclusion: we recognized that one-fifth of the participants were diagnosed with Body Dysmorphic Disorder. Whereas higher rates among those who underwent cosmetic procedures were detected. Therefore, we recommend implementing a Body Dysmorphic Disorder screening tool for patients seeking cosmetic procedures before undergoing it.
Determination the Relationship of Coronavirus Anxiety with Meaning of Life and Life Satisfaction in Adults
Authors: LÖK Neslihan , SEVİNİK Hasan
Published: May 2022

This study was designed to determine the relationship between coronavirus anxiety with the meaning of life and life satisfaction in individuals aged 20-64. The sample population consisted of 386 people between the ages of 20-64 living in Konya central districts. Personal Information Form, Coronavirus Anxiety Scale Short Form, Meaning of Life Scale and Life Satisfaction Scale were used in data collection. The data were collected via social media between January and February 2021. In the descriptive analysis number, percentage, mean and standart deviation; in the correlation analysis Mann Whitney U, Kruskal Wallis tests and Spearman correlation were used. Significant difference was found between coronavirus anxiety scale and gender, educational status, health perception, being Covid-19 positive / suspicious, being in quarantine as a result of being Covid-19 positive / contact and the effect of Covid-19 on the general life. It was determined that coronavirüs anxiety has negative relationship with existing meaning in life and life satisfaciton while has positive relationship with search meaning in life. As a result, it was determined that coronavirüs anxiety differs according to some personal caharacteristics. As the Covid-19 anxiety increases, existing meanning in life and life satisfaciton decreases; and search meaning in life increases. In line with these results, it is recommended to make plans to protect or increase the meaning in life and life satisfaction in a process such as a pandemic that changes life order of the person.
Hydrogeochemical conditions of the Lower-Middle Jurassic complex, the Еm-Еgovsky oil field
Authors: Abdrashitova R. N. , Semenova T. V. , Kadyrov M. A. , Vorobjeva S. V.
Published: May 2022

The research relevance of the structure of deep oil and gas horizons' hydrogeochemical fields in Western Siberia is associated with applied and fundamental issues of oil and gas hydrogeology. The article presents the hydrogeochemical field analysis results of the LowerMiddle Jurassic hydrogeological complex, the Em-Egovsky oil field, which is part of the Krasnoleninsk fields group. The research aim was to establish the reasons for the contrast formation in the hydrogeochemical deposit field. We analyzed ion-salt composition of waters over the area (mainly groundwaters belong to the hydrocarbonate-sodium type according to V. A. Sulin) and revealed a fairly large scatter of salinity values (from 4.5 to 16.1 g/dm3 , with an average value of 8.6 g/dm3 ). Study of the genetic sodium-chloride behavior (values vary from 0.9 to 1.4 with an average of 1.1) and chlorine-bromine coefficients (values vary from 105 to 254.6 with an average of 177.2) in groundwater in combination with the analysis of paleogeographic and tectonic allowed classifying waters as sedimentogenic, undergone significant metamorphization. The conditions for the waters formation made it possible to classify the waters as sedimentogenic, after significant metamorphization. The study of the deposit temperature field gave grounds to assume that one of the reasons for the hydrogeochemical field contrast is the inflow of deep fluids from the basement along faults. In addition, the structure of the hydrogeochemical field was significantly influenced by its formation in the environment of a lithostatic water pumping system and by the feeding province - the Ural framing.
Development of the concept of a multiphase flow meter
Authors: Shulaev N. A. , Nikulin S. G. , Aubakirov R. B. , Puritskis Ja. V. , Motaev K. A.
Published: May 2022

In the oil and gas industry, several problems can be identified that affect the subsequent rates of development of the relevant industry: low quality of oil products and low rates of application of new technologies, which directly slows down the country's economic component. Currently, the development of multiphase flow meters is underway, however, the creation of a universal device is still an unsolved problem, and the existing developments require calibrations. The main problem in calculating the flow rate of the fluid is the determination of the density of the components of the passing mixture. The use of X-ray radiation allows you to solve most of the technical problems, as well as to determine the density with a high accuracy. Flow meters using this concept are of little use. The purpose of the study of our work is to update the applicability of the use of the X-ray range in determining the density of the passing flow. In the course of the work, a search and analysis of tabular data characterizing the interaction of radiation with matter was carried out, according to the results of which acceptable sources of characteristic radiation were determined. In the next step, we modeled the structure of the fluid and derived a system of equations that allows one to determine the densities using existing instruments, as well as constants that are determined experimentally. The result of the research is a solvable system of equations, as well as primary modeling and determination of the component, quantitative composition of the gas-liquid mixture under consideration in laminar flow. The result of this work is to obtain a theoretical confirmation of the relevance of using the device based on this concept, the subsequent addition of characteristic radiation detectors will also help to determine the chemical composition of the fluid.
Relationship of Consanguineous Marriages and Genetic Disabilities Among Children
Authors: Niaz Maham , Ali Shagufta Hamid
Published: May 2022

In a genetic term, “consanguinity” basically is a partnership between couples that are correlated by blood or are second cousins or closer than this. Many countries practise consanguineous marriages like Turkey, Lebanon and Pakistan.The research study aimed to provide information to people about the negative effects of consanguineous marriages. For this purpose, the descriptive research study was conducted in Rawalpindi. Furthermore, people were selected through purposive sampling. The results found that Consanguinity prevails due to caste endogamy and it has a very bad impact on the future generation as it causes a lot of genetic or hierarchical problems. Like many kinds of genetic diseases or problems are very common among the offspring having parents who are cousins by blood. Generally, it is a cultural practice to perform endogamy but has adverse effects on the lives of people. The key factor behind prevailing endogamous marriages is lack of education.
Assessment of Knowledge, Attitude and Practice Regarding Self-Medication Among MBBS and Pharm-D Students in Mirpur District, AJK
Authors: Anjum Adnan , Islam Muhammad Abdul , Iqbal Zafar
Published: May 2022

Self-medication is a common practice among medical and pharmacy students, and it can compromise public trust in this profession. This cross-sectional study determined the self-medication practices among PHARM-D and MBBS students in Mirpur, AJK, through a self-designed questionnaire. The study was performed on a sample of 200 students (mean age =23.60 �1.30 years), 55% (110) were males and 45% (90) were females, out of the 100 were medical students and 100 were pharmacy students. The self-medication prevalence was as high as 75%. Knowledge of MBBS students regarding self-medication was better than PHARM-D students. The common source of advice was textbooks in 56% MBBS and 55% PHARM-D students. The major cause of self-medication was a previous experience, and the most common indications were pain and fever. Therefore, self-medication prevalence was high among students, and potentially harmful drugs sale should be restricted and monitored.
Теорія і практика формування системи знань старшокласників із загальної біології
Authors: Комарова Комарова, Олена Володимирівна
Published: May 2022

У монографії розкрито стан проблеми формування системи знань учнів у педагогічній науці, а саме проаналізовано філософські та психолого-педагогічні підходи до визначення категорії «система знань», у тому числі з точки зору системно-структурного підходу; обгрунтовано виділення методологічних знань фундаментальним елементом системи знань учнів, окреслено їх функції, умови та етапи формування; розглянуто методологічні орієнтири сучасного педагогічного дослідження, серед яких чільне місце належить поліпарадигмальному підходу, що має стати визначальним і при розробці змісту шкільної біологічної освіти у старшій школі; обгрунтовано ідею про те, що основним джерелом системності знань школярів є базова наука; обгрунтовано зміст поняття «система знань старшокласників із загальної біології», описано її якості; схарактеризовано такі елементи системи знань школярів із загальної біології як науковий факт, закон, теорія; визначено методологічні основи формування системи знань із біології в учнів старших класів, описано методи та прийоми формування елементів системи знань про клітинний рівень організації життя, методику формування підсистем генетичних, екологічних, еволюційних знань, подано теоретичне обгрунтування та опис практичного використання методу моделювання біологічних процесів, у тому числі із застосуванням комп’ютерних технологій.
Словник новотворів української мови (кінець 80-х – початок 90-х років ХХ ст.)
Authors: Віняр Г. М. , Шпачук Л. Р.
Published: May 2022

Словник фіксує понад 2000 новотворів, що з'явилися в усному та писемному мовленні кінця 80-х – початку 90-х років ХХ століття. Джерелом надходження стала мова періодичних видань, творів художньої літератури, усне розмовне мовлення, окремі наукові та науково-популярні видання. Матеріал словника може бути використаний при написанні курсових і дипломних робіт з проблем новітнього словотворення, при викладанні спецкурсу у вузі або факультативу у середній школі, при укладанні словників різних типів.
Computer Simulation of Biological Processes at the High School
Authors: Комарова Олена Володимирівна , Азарян Альберт Армаїсович
Published: May 2022

Abstract. Research goals: the necessity of study in high school of the law of Hardy – Weinberg as one of the fundamental genetic laws was justified. The peculiarities of using the method of model experiment in the study of the genetic and evolutionary processes in populations with the use of computer technology. Object of research: computer simulation of population genetic structure. Subject of research: computer simulation of genetic and evolutionary processes in ideal and real populations. Research methods: pedagogical experiment (survey), analysis of scientific publications on the use of the high school method of modelling genetic and evolutionary processes in populations, computer simulation. Results of the research: a web page for processing by the pupils of the modelling results of genetic and evolutionary processes in populations was created.
Proceedings of the 7th Workshop on Cloud Technologies in Education (CTE 2019), Kryvyi Rih, Ukraine, December 20, 2019
Authors: Shyshkina Mariya P.
Published: May 2022

This volume represents the proceedings of the 7th Workshop on Cloud Technologies in Education (CTE 2019), held in Kryvyi Rih, Ukraine, in December 20, 2019. It comprises 42 contributed papers that were carefully peer-reviewed and selected from 66 submissions. The accepted papers present the state-of-the-art overview of successful cases and provides guidelines for future research. The volume is structured in four parts, each presenting the contributions for a particular workshop track.
Розвиток креативності викладача англійської мови як необхідної складової навчального процесу у вищій школі
Authors: Гарлицька Т. С.
Published: May 2022

У статті розглянуто особливості та етапи розвитку креативності педагога вищої школи; проаналізовано форми, методи та прийоми, які слід використовувати у педагогічній діяльності для вдосконалення творчих умінь та навичок. Також акцентовано увагу на важливості розвитку креативності викладача англійської мови та запропоновано шляхи формування творчих здібностей викладача. Важливе значення у статті надається також зв’язку креативності викладача із розвитком творчого потенціалу студентів англомовного профілю.
Тенденції розвитку нелітературних одиниць (на матеріалі української, російської та англійської мов)
Authors: Гарлицька Т. С.
Published: May 2022

Статтю присвячено дослідженню тенденцій розвитку некодифікованих елементів в умовах глобалізації та демократизації суспільства. Характерні риси та можливості розвитку субстандартних одиниць вивчаються крізь призму екстра- та інтралінгвальних чинників, які є рушіями нових тенденцій розвитку будь-якої мови.
Лінгвосоціокультурні особливості міського мовлення крізь призму жаргонних фразеологізмів
Authors: Гарлицька Т. С.
Published: May 2022

Стаття присвячена дослідженню лінгвокультурних та соціолінгвістичних особливостей міського мовлення на матеріалі жаргонних фразеологізмів. У роботі аналізуються та порівнюються жаргонні фразеологічні системи української, російської та англійської мов шляхом визначення основних семантичних та соціальних груп фразеологічних жаргонізмів, їх національно-культурної своєрідності та функціонального призначення. На основі спільних лінгвосоціокультурних рис, притаманних жаргонним фразеологічним одиницям трьох досліджуваних мов, визначаються загальні тенденції розвитку міського мовлення.
Соціолінгвістичні особливості професійних жаргонізмів (на матеріалі української, російської та англійської мов)
Authors: Гарлицька Т. С.
Published: May 2022

Статтю присвячено дослідженню професійних жаргонізмів у соціолінгвістичному аспекті. Професійні жаргонізми розглядаються у складі нелітературних одиниць як феномен міського мовного побуту. У ході дослідження з’ясовано, що в системі професіоналізмів української, російської та англійської мов найчастотнішими є лексеми військової, комп’ютерної, музичної та спортивної сфер, що є об’єднуючим чинником трьох народів. Уживання військових професіоналізмів активізувалося в період військових дій між Україною та Росією, які мають безпосередній уплив на економічне, політичне, мовне життя інших країн, зокрема США. Переважна більшість військових жаргонізмів має негативно забарвлене значення, що виражає зневажливе, іронічне ставлення мовця, спрямоване на приниження особи, до якої звертаються
Кривбас – територія екологічної небезпеки
Authors: Антонік Ірина Петрівна , Антонік Валерій Іванович , Штанько Людмила Олександрівна
Published: May 2022

Криворізький залізорудний басейн є одним із найпотужніших індустріальних центрів України, де на відносно невеликій території сконцентровано десятки гірничо-видобувних підприємств, металургійне виробництво повного циклу та низка обслуговуючих підприємств. Багаторічне ведення економічної діяльності за принципами фронтальної економіки техногенного типу призвело до глибоких і незворотних зрушень на різних екологічних рівнях в стані літосфери і гідросфери регіону, завдало значних змін ландшафтним утворенням, здійснює безперервний негативний вплив на стан атмосфери. Усе це визиває глибоку занепокоєність стосовно майбутнього Криворізького краю та умов проживання населення.
MHC I Expression Predicts Response to Checkpoint Inhibitors in Metastatic Urothelial Carcinoma but Lacks Prognostic Value in Localized Disease
Authors: Slotta-Huspenina Julia , Schwamborn Kristina , Steiger Katja , Simon Ricarda , Kirchhoff Florian Paul , Büchler Jakob Wolf , Fiedler Julia , Retz Margitta , Nawroth Roman , Ritschel Christoph , Gschwend Jürgen Erich , Horn Thomas
Published: May 2022

BACKGROUND:

Loss of MHC I expression is a tumoral escape mechanism, part of the process of immunoediting. MHC expression patterns and their prognostic and predictive value have not been studied in urothelial carcinoma of the bladder (UC) so far.

OBJECTIVE:

To correlate the expression of MHC I and MHC II with prognosis after curative treatment, response to chemotherapy and checkpoint inhibition.

PATIENTS AND METHODS:

We analyzed different patient cohorts for their expression of MHC I(HLA-A/B/C) and II (HLA-DR/DP/DQ) and examined potential correlations with prognosis and response to cisplatin-based chemotherapy or PD-1/PD-L1 directed immunotherapy.

RESULTS AND LIMITATIONS:

Overall, MHC expression was analyzed in 246 patients, and complete MHC I loss was seen in 29.7% of patients. In 35% of patients aberrant tumoral expression of MHC II was observed. In a homogeneous cohort of 149 patients with cystectomy with curative intent there were no significant differences in survival between the MHC expression groups. MHC I+ and MHC II+ patients had higher infiltration densities with CD8+ T effector cells. An analysis of 77 additional patients (cohort II) with neoadjuvant chemotherapy revealed no associations of MHC status with response defined as < pT2 pN0 in the cystectomy specimen. Lastly, we analyzed 26 patients with metastatic disease treated with PD-1/PD-L1 directed immunotherapy (cohort III, best response: 11 PD, 5 SD, 10 OR) and observed responses exclusively in MHC I+ patients (10/19 patients, 52.6). All four MHC I+ /MHC II+ /PD-L1+ patients had a progression-free interval of at least 12 months.

CONCLUSIONS:

Tumoral MHC I expression is frequently lost in UC. We found no association with prognosis or response to cisplatin-based chemotherapy but response to checkpoint inhibitors was limited to MHC I+ patients.
Beneficial Effects of Snail Helix aspersa Extract in an Experimental Model of Alzheimer’s Type Dementia
Authors: Tancheva Lyubka , Lazarova Maria , Velkova Lyudmila , Dolashki Alexander , Uzunova Diamara , Minchev Borislav , Petkova-Kirova Polina , Hassanova Yozljam , Gavrilova Petja , Tasheva Krasimira , Taseva Teodora , Hodzhev Yordan , Atanasov Atanas G. , Stefanova Miroslava , Alexandrova Albena , Tzvetanova Elina , Atanasov Ventseslav , Kalfin Reni , Dolashka Pavlina
Published: May 2022

Background: Alzheimer’s disease (AD) is a complex neurodegenerative disease with multifactorial etiology, unsatisfactory treatment, and a necessity for broad-spectrum active substances for cure. The mucus from Helix aspersa snail is a mixture of bioactive molecules with antimicrobial, anti-inflammatory, antioxidant, and anti-apoptotic effects. So far there are no data concerning the capacity of snail extract (SE) to affect neurodegenerative disorders. Objective: The effects of SE from Helix aspersa on learning and memory deficits in Alzheimer’s type dementia (ATD) induced by scopolamine (Sco) in male Wistar rats were examined and some mechanisms of action underlying these effects were evaluated. Methods: SE (0.5 mL/100 g) was applied orally through a food tube for 16 consecutive days: 5 days before and 11 days simultaneously with Sco (2 mg/kg, intraperitoneally). At the end of Sco treatment, using behavioral methods, we evaluated memory performance. Additionally, in cortex and hippocampus the acetylcholinesterase (AChE) activity, acetylcholine and monoamines (dopamine, noradrenaline, and serotonin) content, levels of main oxidative stress markers, and expression of brain-derived neurotrophic factor (BDNF) and cAMP response element-binding protein (CREB) were determined. Results: We demonstrated that, according to all behavioral tests used, SE significantly improved the cognitive deficits induced by Sco. Furthermore, SE possessed AChE inhibitory activity, moderate antioxidant properties and the ability to modulate monoamines content in two brain structures. Moreover, multiple SE applications not only restored the depressed by Sco expression of CREB and BDNF, but significantly upregulated it. Conclusion: Summarizing results, we conclude that complex mechanisms underlie the beneficial effects of SE on impaired memory in Alzheimer’s type dementia.
Ratio component-wise design method of fuzzy c-means clustering validity function
Authors: Wang Guan , Wang Jie-Sheng , Wang Hong-Yu , Liu Jia-Xu
Published: May 2022

Fuzzy clustering is an important research field in pattern recognition, machine learning and image processing. The fuzzy C-means (FCM) clustering algorithm is one of the most common fuzzy clustering algorithms. However, it requires a given number of clusters in advance for accurate clustering of data sets, so it is necessary to put forward a better clustering validity index to verify the clustering results. This paper presents a ratio component-wise design method of clustering validity function based on FCM clustering method. By permutation and combination of six clustering validity components representing different meanings in the form of ratio, 49 different clustering validity functions are formed. Then, these functions are verified experimentally under six kinds of UCI data sets, and a clustering validity function with the simplest structure and the best classification effect is selected by comparison. Finally, this function is compared with seven traditional clustering validity functions on eight UCI data sets. The simulation results show that the proposed validity function can better verify the classification results and determine the optimal clustering number of different data sets.
Collaboration in the context of supporting people with mental health and addiction issues into employment: A scoping review
Authors: Wharakura Mary-Kaye , Lockett Helen , Carswell Peter , Henderson Geraldine , Kongs-Taylor Heather , Gasparini Jessica
Published: May 2022

BACKGROUND: People with mental health and addiction issues have significantly lower levels of labor force participation than the general population. How organizations collaborate, particularly employment and health services, influence this disparity. Whilst collaboration has been examined, investigation of the role of collaboration context is limited. OBJECTIVE: To identify what affects collaboration to support people with mental health and addiction issues into employment. METHODS: A review and synthesis of the collaborative healthcare literature identified important a priori factors at macro, meso, and micro levels. A targeted scoping review of vocational rehabilitation literature identified the collaboration factors most relevant to supporting people with mental health and addiction issues into employment. RESULTS: Twenty articles met the inclusion criteria for the scoping review. Whilst some factors affecting collaboration aligned across these different contexts, there were notable differences. The vocational rehabilitation literature emphasized roles and responsibilities, contracting, training and technical assistance, sharing information, relationship continuity and practitioner value alignment. There was less emphasis in the vocational rehabilitation literature on practitioners’ beliefs about collaboration, how agencies work together around the person, and on infrastructure support. CONCLUSIONS: Collaboration in the context of supporting people with mental health and addiction issues into employment needs planning and support. Whilst many factors known to enable collaboration remain important, the collaboration context matters.
Clinical and echocardiographic characteristics associated with evolution of patent ductus arteriosus in preterm neonates: A prospective cohort study
Authors: Saha A.K. , Sardar S.K. , Majhi B. , Chatterjee S.
Published: May 2022

BACKGROUND: In preterm infants, persistence of ductus arteriosus is an important medical condition. Functional echocardiography for patent ductus arteriosus (PDA) may guide clinical decision-making regarding treatment requirement strategies. Objectives of the study were to assess the trends of clinical and functional echocardiographic parameters with evolution of ductus arteriosus in babies≤1250 gm of birth weight and to evaluate whether there is any association of these parameters with persistence of ductus. METHODS: In this prospective observational study, recruited babies were assessed serially for clinical events and functional echocardiography. Babies were classified into three groups: without PDA, with PDA but PDA spontaneously closed (within 7 days) and persistent PDA. RESULT: We included 143 infants (Birth weight 1017±179 g, gestational age 30.8±2.7 weeks). Out of 60 babies with PDA, PDA failed to close spontaneously in first week in 32 (53.4 %) infants. PDA Doppler flow pattern on day 3 was found to be one of the most significant markers for future ductus. The highest frequency of growing pattern (37.5%) and pulsatile pattern (59.4%) was seen in persistence ductus group. PDA diameter and LA/Ao ratio were found strongly correlated with all other variables except E/A ratio. CONCLUSION: We noticed persistence of ductus in preterm infants had significant clinical and echocardiographic association. PDA doppler flow pattern on day 3 was found to be a significant marker for future behaviour of ductus. Significant correlation was found among individual functional echocardiographic parameters in babies with PDA. This would guide judicious treatment of PDA in preterm neonates.
Fluid and electrolyte management in preterm infants with patent ductus arteriosus
Authors: Lalitha R. , Surak A. , Bitar E. , Hyderi A. , Kumaran K.
Published: May 2022

Optimal fluid management of preterm babies with suspected or confirmed diagnosis of patent ductus arteriosus (PDA) is frequently challenging for neonatal care physician because of paucity of clinical trials. There is wide variation in practice across neonatal units, resulting in significant impact on outcomes in Extremely Low Birth Weight (ELBW) babies with hemodynamically significant PDA. A delicate balance is required in fluid management to reduce mortality and morbidity in this population. The purpose of this review is to lay out the current understanding about fluid and electrolyte management in ELBW babies with hemodynamically significant PDA and highlight areas for future research.
Proprioceptive based training or modified constraint-induced movement therapy on upper extremity motor functions in chronic stroke patients: A randomized controlled study
Authors: Alaca Nuray , Öcal Numan Melik
Published: May 2022

BACKGROUND: The Modified Constraint-Induced Movement Therapy (mCIMT) method is a unilateral training that respectively avoids and activates less affected and affected sides of upper extremities; however, the selected options are not typically ideal. Proprioceptive based training (PT) includes bilateral training methods and influencing proprioceptive receptors. OBJECTIVE: The primary purpose was to determine if conventional therapy and PT or conventional therapy and mCIMT therapy show similar improvement in patients with chronic stroke. The secondary purpose was to investigate the effectiveness of conventional therapy and PT or mCIMT therapy in patients with chronic stroke and to compare which of the two interventions is more effective. METHODS: Forty patients with chronic stroke were randomly allocated to only conventional therapy (PTR, n = 14), conventional therapy plus proprioception training (PTR-PT, n = 13), and mCIMT (PTR-mCIMT, n = 13) groups. Evaluations were assessed before and 6 weeks after treatment. RESULTS: Intragroup evaluations revealeda significant improvement in the all scores in the PTR-PT and PTR-mCMIT groups (p = 0.006 < 0.001). Intergroup comparisons demonstrated that the PTR-mCIMT group had a significant improvement in spasticity and motor function scores compared to the PTR (p < 0.001) and the PTR-PT groups (p = 0.006–0.015). CONCLUSIONS: PT and mCMIT applied in addition to conventional therapy in patients with chronic stroke were more effective than only conventional therapy. Additionally, mCMIT showed greater improvement in spasticity and motor function scales than PT.
Neuropsychological manifestations of long COVID in hospitalized and non-hospitalized Brazilian Patients
Authors: Braga L.W. , Oliveira S.B. , Moreira A.S. , Pereira M.E. , Carneiro V.S. , Serio A.S. , Freitas L.F. , Isidro H.B.l. , Souza L.M.N.
Published: May 2022

BACKGROUND: There has been a significant increase in number of patients seeking neuropsychological rehabilitation months after the acute phase of COVID-19 infection. OBJECTIVE: Identify the cognitive and psychiatric disorders in patients with long COVID or Post-Acute Sequelae of COVID (PASC) and explore the association between disease severity during the acute phase and persistent neuropsychological manifestations. METHODS: 614 adults were assessed an average of eight months post-infection. Participants were, on average, 47.6 y.o., who sought rehabilitation for neuropsychological problems. Patients were evaluated using the Barrow Neurological Institute Screen for Higher Cerebral Functions (BNIS), Phonemic Verbal Fluency and Clock Drawing tests (NEUPSILIN) for executive functions, and the Hospital Anxiety and Depression Scale (HADS). RESULTS: The BNIS score was significantly below reference values in all subscales, especially affect and memory. Verbal Fluency and Clock Drawing subtest results were also lower. Patients with PASC tested high for anxiety/depression, but there was no statistically significant relationship between HADS and BNIS scores. Neuropsychological evaluations showed no differences in cognitive or psychiatric profiles between hospitalized and non-hospitalized patients. CONCLUSIONS: Neuropsychological results suggest executive function problems and high incidence of anxiety/depression, irrespective of acute-phase severity, underscoring a need for neurorehabilitation programs while providing data for public policy initiatives.
METHODICAL COMPONENTS OF FORMATION OF DIAGNOSTICINFORMATION SUBSYSTEM OF ENSURING FUNCTIONALTECHNOLOGICAL RELIABILITY OF EXECUTORS OF THE CONSTRUCTION PROJECT
Authors: Zhаldak Ruslan
Published: May 2022

The article considers the modern practice of urban innovation, based on the principles of biosphere compatibility. The project solution of providing organizational and technological reliability of construction from the point of view of the possibility of realizing the functions of a biosphere compatibility city and introducing innovative constructive and architectural and planning solutions is analyzed. In relation to the construction project, the formalization of the methodology for calculating the indicators of the biosphere compatibility of cities and settlements, the quantitative indicators of the implementation of the functions of the city are determined. The obtained results of numerical analysis of the realization of city functions can predict the development of urban areal, assess the comfort and safety of the urban environment from the standpoint of biosphere compatibility of construction objects in order to harmonize the characteristics of the life cycle of these projects with the characteristics of the microenvironment of their implementation. The basis of such tools is: multifactorial, multicomponent modeling and multicriterial selection of alternatives for building construction for projects, provided that the level of biosphere compatibility is used as the leading analytical coordinate of such simulation. These models, implemented in the format of modern construction, will serve as a basis for organizational and technological and environmental expertise of projects.
INNOVATIONS REGARDING STATE REGISTRATION OF LAND USE RESTRICTIONS IN THE STATE LAND CADASTRE
Authors: Mykhalova Mariia
Published: May 2022

The article considers innovations in the state registration of land use restrictions in the state land cadastre. In order to establish the optimal regime of land use, the law defines land use restrictions, which are designed in a comprehensive plan of spatial development of the territorial community, master plan of the settlement, detailed plan of the territory and subject to state registration in the State Land Cadastre. The sequence of state registration of land use restrictions is considered. This article considers only the rules on state registration of restrictions on land use, which came into force in 2021. Particular emphasis is placed on changes in the legislation on registration of restrictions on land use, namely: types of land use restrictions subject to state registration and the grounds on which the State Land Cadastre enters information (changes to them) on restrictions. At the legislative level, both land and urban planning legislation defines all types of restrictions, including restrictions defined by sectoral norms on land management, land protection, etc.
PROBLEMS OF THE REVITALIZATION OF RURAL SETTLEMENTS IN UKRAINE IN THE CONTEXT OF SUSTAINABLE DEVELOPMENT
Authors: Tretiak Yuliia , Timokhin Viktor , Shebek Nadiia , Tretiak Maxim
Published: May 2022

The authors of the article considered the problem of the revitalization of the environment of rural settlements of Ukraine, which occupies one of the leading plac-es in the process of transition of the state to sustainable development. Today, Ukraine is taking the first steps in the transition period to sustainable development, and at this stage, the development - renewal, modernization, revitalization - of rural areas and settlements, which occupy about 63.5% of the country's territory, is gaining signifi-cant importance.

The authors analyzed the strategic documents of the international and state lev-els, which determine the goals of transformation of all spheres of life of the country. Various aspects of understanding the process of development of rural settlements in Ukraine today are considered, in particular, based on the strategy of sustainable de-velopment. The paper highlights the results of theoretical elaboration of more than ten years of experience in designing master plans of rural settlements of Kyiv, Dnipropetrovsk, Sumy regions, to further identify patterns and establish principles of the revitalization of rural settlements based on sustainable development. This will help to predict future transformations of their structure, as well as to form the archi-tectural planning and spatial organization of settlements.

The results of the study of theoretical sources and practice of designing rural settlements allowed us to identify several features that characterize the process of formation of a balanced and harmonious environment of settlements located in rural areas, as well as to systematize and determine the promising directions of their revi-talization based on sustainable development. The authors establish the types of func-tional orientation (specialization) of rural settlements production in Ukraine: logis-tics; crop and livestock production; Food Industry; tourism - ecological and ethnic; recreation and rehabilitation; science-intensive innovative production, etc. Multifac-tor analysis of resources and defined specialization of production provides an oppor-tunity to divide rural settlements into "promising" and "unpromising", and according to development options promising settlements in the direction of a certain "speciali-zation" to divide into mono-profile and multi-profile.
MODELING AND ALGORITHM FOR CALCULATION OF PARAMETERS OF THE ROOM MICROCLIMATE REGULATION SYSTEM WITH ARTIFICIAL INTELLIGENCE ELEMENTS.
Authors: Chоvniuk Yuriy , Cherednichenko Petro , Moskvitina Anna
Published: May 2022

The depletion of traditional fuel resources and the deterioration of the ecology of the environment, an increase in emissions into the atmospheric air makes research on the efficient use of energy resources in indoor climate control systems topical. A promising direction is to increase the degree of intellectualization of management, as well as to take into account the conditions of human life and the introduction of features of subjective assessment of processes and events in technical systems. The issues of control and regulation of microclimate parameters in all types of premises, where comfortable conditions for a person's stay or ensuring the necessary parameters for the technological process are an important factor, is the task of systems with fuzzy logic. Intelligent control systems evaluate the parameters of the microclimate in the room and automatically select the operating mode of the corresponding devices that provide the comfortable parameters of this microclimate with the efficient use of energy resources for this. The choice is based on practical analysis - the average wishes of people using this room, as well as standard indicators of temperature, humidity and air pollution, which are necessary for a comfortable stay of a person in a room or to ensure a technological process, are taken as a standard. In addition, the change in temperature and humidity indicators in the room is taken into account when the internal or external conditions change. This article substantiates a model and an algorithm for calculating the parameters of a room microclimate control system with elements of artificial intelligence (based on the methods of the theory of fuzzy sets). The application of the mathematical apparatus of fuzzi-logic for solving the problems of developing a control system for the microclimate of premises is proposed, which makes it possible to take into account the subjective factors of human perception of the parameters of the environment in the technical system. Various cases of regulating the parameters of the microclimate of the premises are considered and the rules for regulating the parameters of the microclimate of the premises to their comfortable values are generalized.
ANALYSIS OF MODERN METHODS FOR TECHNICAL SURVEY OF BUILDINGS AND STRUCTURES
Authors: Biloshytska Nataliia , Tatarchenko Zakhar , Reveka Artem , Lobko Darіа
Published: May 2022

The article analyzes modern methods for monitoring the technical operation of buildings and structures. Technical inspection of buildings and structures is a separate type of construction activity. The necessity for a technical survey is caused by the physical and moral deterioration of building structures and changes of terms of use, as well as the absence in building codes of an explicit account of the time factor. Ensuring the operability of structures at a specific moment of existence requires a set of measures that differ from the design, manufacture and installation of building elements associated with the creation of normal conditions for the life of enterprises in industrial buildings and structures and, above all, the safety of the operation process. 

Specialists in the technical operation of buildings and structures have new tools for more accurate determination of defects and supervision of buildings and structures. The emergence and development of IT technologies, in particular, the use of mathematical, computer modeling techniques have demonstrated unprecedented opportunities for a comprehensive approach to testing the performance of buildings. Most modern methods of technical inspection of buildings do not require significant financial and labor costs; they can be directly implemented both during the planning of the facility and during its operation without reducing the bearing capacity of structures, unlike classical methods (visual, visual-instrumental, etc.). Their goal is to control the technical condition of building structures and early diagnosis of threats to the existence of the object. The integrated use of these methods at different stages of the life cycle of buildings will increase their service life and the comfort and safety of staying in them.
MULTICULTURALLY COMPLEXES. ARCHITECTURAL AND PLANNING FEATURES
Authors: Zhovkva Olha
Published: May 2022

The issue of finding the mechanisms for interaction between different cultures and religions is relevant today for many countries of the world. In the context of globalization, the establishment of intercultural ties is an extremely important process. Despite this, the issue of creating a comfortable multicultural environment for training tolerant, highly educated public and religious figures is still insufficiently researched. The objective of this study is to develop conceptual foundations for the formation of multicultural and polyreligious spiritual educational complexes as a new “universal” enlarged type of spiritual educational institution for representatives of various religions and confessions (Christian, Muslim, Jewish), as well as recommendations regarding their design, taking into account religious and confessional features. During the study, we used theoretical and empirical research methods. Based on that, the principles of the architectural and planning organization of a multicultural polyreligious spiritual educational complex are formulated, where all levels of spiritual education (primary, secondary, higher) and all functions necessary for comprehensive education, as well as intellectual and spiritual development, are presented in a holistic manner. It is concluded that the use of the developed and proposed scientific principles in the design of these objects will contribute to the formation of a harmonious multicultural and polyreligious educational environment.
Optimal Cash Ratio and Adjustment Speed Across Different Firm Characteristics
Authors: Otaify Mahmoud , Dawood Aly , Farouk Mohamed
Published: May 2022

This paper seeks to use fixed effect and dynamic panel models to examine role of firm characteristics, macroeconomic variables, control of corruption and political uncertainty in explaining cash holdings of Egyptian firms over the period 2011 – 2020. We find that firm characteristics strongly explain variations in corporate cash ratios and deviations from the target ratios. However, we document no considerable role of macro variables. Egyptian firms tend to hold liquid assets as cash substitutes in managing their working capital and use debt as cash substitute in financing their operations. The findings support the prediction of main corporate finance theory and support both the precautionary and transactionary motives to hold cash. As expected, Egyptian firms tend to hold more cash during periods of high political uncertainty.  After sorting according to the most influential independent variables which are tangibility and dividend yield (high and low). We find that cash holdings of the firms respond differently to both the firm specific variables and macro variables. Specifically, the high tangibility firms adjust their cash holding to the optimal level faster than the low tangibility firms while the low dividend yield firms adjust faster than the high dividend yield firms. The results of dynamic panel models indicate that Egyptian firms follow a partial adjustment policy towards the optimal cash levels, which corresponds with trade off theory.
PERHITUNGAN ECONOMIC DISPATCH TIGA BUAH PEMBANGKIT TANPA LOSSES DENGAN METODE MERIT ORDER
Authors: Safarudin Yanuar Mahfudz , Stephani Ribka , Aulia Nur Fatowil , Su’udy Ahmad Hamim , Apriandi MS Nanang , Hermawan Baktiyar Mei
Published: May 2022

Merit order merupakan suatu metode yang digunakan dalam tahap economic dispatch. Metode ini merupakan metode yang paling sederhana, apabila dibandingkan dengan metode lain. Metode ini dilakukan dengan cara mengurutkan pembangkit dari yang paling murah hingga yang paling mahal berdasarkan biaya operasinya. Semakin rendah nilai biaya operasi (Rp/MWh) suatu pembangkit, maka dapat dikatakan pembangkit tersebut semakin ekonomis. Penelitian ini membahas mengenai penggunaan metode merit order untuk menghitung daya yang dibangkitkan pada masing-masing pembangkit. Terdapat tiga pembangkit yang digunakan untuk mencatu beban sebesar 975 MW. Simulasi digunakan dalam kondisi tanpa losses. Hasil menunjukkan bahwa merit order merupakan metode yang sederhana dan membantu dispatcher untuk mengambil keputusan lebih cepat. Kemudian SOP dari metode merit order dibuat berdasarkan biaya operasi pembangkit sehingga harus selalu di update sesuai perubahan harga bahan bakar.
RANCANG BANGUN PROTOTYPE PEMBANGKIT TURBIN ANGIN SKALA MIKRO TIPE HORIZONTAL DOUBLE MULTIFLAT BLADE DENGAN VARIASI JUMLAH SUDU
Authors: Sahid Sahid , Prasetyo Budhi , M.S Ulya , E.H. Yoga , H. R Afrida , A.S. Muhammad
Published: May 2022

Kelebihan dari turbin angin poros horizontal yaitu efisiensinya lebih tinggi dibanding turbin angin poros vertikal karena sudu selalu bergerak lurus terhadap arah angin dan menerima daya sepanjang putaran. Tujuan dari tugas akhir ini dibuat untuk mengembangkan tugas akhir tahun 2018 dengan memvariasikan jumlah sudu yaitu 9, 12, dan 15 dan membandingkan kinerja turbin angin dengan menggunakan variasi kecepatan angin. Metode yang digunakan yaitu dengan melakukan tahap penelitian berupa merancang, membuat, dan merakit turbin angin. Turbin angin memiliki dimensi panjang sudu sebesar 650 mm, lebar sisi masuk 60 mm, dan lebar sisi keluar 80 mm. Sedangkan hub memiliki diameter 68,8 mm dan tinggi kerangka 1,5 m. Variabel penelitian meliputi variasi jumlah sudu yaitu 9 buah, 12 buah, dan 15 buah. Data dari hasil pengujian ini kemudian dibuat tabel dan dibandingkan dengan menganalisa grafik karakteristik putaran dan efisiensi. Tahap akhir dari pengujian ini yaitu untuk mendapatkan efisiensi sistem terbaik dengan variabel yang digunakan. Nilai efisiensi pada sudu 9 yaitu sebesar 1,41% pada kecepatan angin 5,15 m/s, pada sudu 12 yaitu sebesar 2,59% pada kecepatan angin 5,58 m/s, dan pada sudu 15 yaitu sebesar 2,68% pada kecepatan angin 5,7 m/s
STUDI NUMERIK BACKWARD –FACING STEP FLOW DENGAN ADANYA BUMP SETENGAH LINGKARAN DISERTAI VARIASI JARAK BUMP PADA MODEL TURBULEN K-EPSILON
Authors: Aulia Nur Fatowil , Wijaya Adi Chandra , Hermawan Baktiyar Mei , Su’udy Ahmad Hamim
Published: May 2022

Studi backward-facing step yang menggunakan turbulent model k- ε (RNG, Realizable) dengan standard wall functions. Sebuah bump ditempatkan di dekat posisi saluran masuk dalam bentuk setengah lingkaran. Studi dimulai dengan melakukan uji grid independency test tanpa menggunakan bump. Metode simulasi yang digunakan dalam studi ini adalah: jarak ketinggian (h): 14; variasi jarak bump (I / h): 2, 4; diameter melingkar (D): 14. Studi ini menggunakan bilangan Reynolds pada 38000 (v = 40.9 m/s). Hasil dari studi ini adalah membandingkan variasi model yang memiliki perbedaan jarak posisi bump dan beberapa model K-epsilon. Dengan tambahan bump setengah lingkaran maka reattachment length menjadi lebih pendek yang memiliki selisih sekitar 6 - 11% pada jarak bump I/h = 2 dan 34 - 42% untuk jarak bump I/h = 4 jika dibandingkan dengan reattachment length tanpa bump