bluuebunny/crossref_metadata_2025 huggingface dataset:
Implementasi Sinici Kudo Apps pada Peternakan Kelinci Peci P’Rama di Kabupaten Tulungagung
Authors: Fadhillah Arief Rizki , Iriananda Syahroni Wahyu , Purnomowati Wiwin , Nugroho Kuncahyo Setyo , Akbar Ismail , Sakinah Renada Julia
Published: February 2023

Broiler rabbits have a very high potential to improve the community's economy. In addition, rabbits can also be a potential source of animal protein as an alternative food for the community. Peci P'Rama (Home Broiler Rabbit Breeder) is a broiler rabbit farming business initiated in October 2017. The problems of Peci P'Rama in running a broiler rabbit farm, among others: have not carried out the codification/identification of broiler rabbits owned according to standards, and the financial management carried out is not well organized and structured. In solving the problems faced by Peci P'Rama partners, the implementing team designs activity methods for problem-solving: Planning, Analysis, Problem Identification, Design, Implementation, Testing and Integration, Training and Mentoring, Maintenance, Evaluation of the Use of Indonesia's Leading Rabbit Farm Information System (SiNiCi Kudo) Mobile Based. Based on the results of the Sinici Kudo application on the Peci P'Rama rabbit farm, it can be concluded that with the implementation of the Sinici Kudo application on the P'Rama rabbit farm, an increase in rabbit productivity and financial management went well and was recorded neatly.ABSTRAKTernak kelinci pedaging memiliki potensi yang sangat tinggi dalam meningkatkan perekonomian masyarakat. Selain itu, ternak kelinci juga dapat sebagai potensi sumber protein hewani alternatif pengan bagi masyarakat. Peci P’Rama (Peternak Kelinci Pedaging Rumahan) merupakan usaha ternak kelinci pedaging yang dirintis sejak Bulan Oktober Tahun 2017. Permasalahan Peci P’Rama dalam menjalankan peternakan kelinci pedaging, antara lain : belum melakukan kodifikasi/pemberian identitas pada kelinci pedaging yang dimiliki sesuai standar, pengelolaan keuangan yang dilakukan belum tertata dan terstruktur baik. Dalam menyelesaikan permasalahan yang dihadapi mitra Peci P’Rama, maka tim pelaksana merancang metode kegiatan untuk penyelesaian permasalahan : Planning, Analisis dan Identifikasi Masalah, Desain, Implementasi, Ujicoba dan Integrasi,  Pelatihan dan Pendampingan, Maintanance, Evaluasi Penggunaan Sistem Informasi Peternakan Kelinci Unggulan Indonesia (SiNiCi Kudo) Berbasis Mobile. Berdasarkan hasil implementasi aplikasi sinici kudo pada peternakan kelinci Peci P’Rama, maka dapat disimpulkan bahwa dengan implementasi Aplikasi Sinici Kudo pada peternakan kelinci P’Rama didapatkan peningkatan produktifitas ternak kelinci dan pengelolaan keuangan berjalan dengan baik dan tercatat dengan rapi.Kata Kunci : ternak kelinci,  Sinici kudo, kodefikasi, Keuangan
Pelatihan Pembuatan Insektisida Hayati Pada Kelompok Tani Apel Di Batu Jawa Timur
Authors: Indratmi Dian , Hartawati Hartawati , Wulandari V. Safitri , Rachmawan Muhammad Danang
Published: February 2023

Community service activities were carried out in the Batu area with apple farmer group partners in Giripurno Village, Bumiaji District. Apple farmer groups experienced a decline in apple production which was getting worse due to the widespread attack of apple pests and the challenge of conventionally controlling synthetic chemical pesticides. The activity aims to improve the household welfare of apple farmers and apple production through training on applying appropriate technology for biological insecticides as an alternative to controlling apple pests. The activities are carried out using training methods, counseling, consultation, demonstration plots, and assistance in manufacturing techniques, mass production, and application of biological insecticides. The activity results showed an income and apple production increase by 75%, reduced pest attacks, and healthier plant growth. Increased motivation of apple farmers from low to high.ABSTRAKKegiatan pengabdian pada masyarakat  dilaksanakan  di daerah Batu dengan mitra kelompok tani apel Desa Giripurno, Kecamatan Bumiaji.  Kelompok tani apel mengalami penurunan produksi apel yang semakin parah akibat maraknya serangan hama apel dan sulit dikendalikan dengan cara konvensional menggunakan pestisida kimia sintetik. Kegiatan bertujuan  meningkatkan kesejahteraan rumah tangga petani apel dan produksi apel melalui pelatihan penerapan teknologi tepat guna insektisida hayati sebagai alternatif pengendalian hama apel. Kegiatan dilaksanakan dengan metode pelatihan, penyuluhan, konsultasi, demplot, dan pendampingan dalam hal teknik pembuatan, produksi massal, dan aplikasi insektisida hayati di lapang. Hasil kegiatan menunjukkan bahwa terjadi peningkatan pendapatan dan produksi apel sebesar 75%; penurunan serangan hama, serta pertumbuhan tanaman yang lebih sehat. Meningkatnya  motivasi petani apel yang semula rendah menjadi tinggi.
Pemberdayaan Pedagang Sayur Keliling Melalui Program “Abang Sayur” dalam Upaya Peningkatan Penjualan di Era Covid-19
Authors: Dyanasari Dyanasari , Trianawati Anis , Arvianti Eri Yusnita
Published: February 2023

This community service program aims to provide counseling about increasing sales of vegetable products through the concept of "Abang Sayur," which pays attention to the quality and marketing methods through online to mobile vegetable traders. At this time, problems were found due to government policies amid the Covid-19 pandemic. Restrictions on movement and space trigger limitations for traders to move during the pandemic, resulting in a decrease in the sales turnover of mobile vegetable traders. With the problems that occur, the solutions offered are to provide direction and strategies to increase sales of vegetable products through online marketing and carry out promotional strategies through social media. The results of this extension activity can help increase farmers' income and sales turnover by up to 70%, better packaging, selling labels, financial reports, and product sales through online marketing on Whatsapp Business.ABSTRAKProgram pegabdian masyarakat ini bertujuan untuk memberikan penyuluhan tentang peningkatan penjualan produk sayuran melalui konsep “abang sayur”, yaitu memperhatikan kualitas dan cara pemasaran melalui online kepada pedagang sayuran keliling. Pada saat ini, permasalahan ditemukan akibat kebijakan pemerintah ditengah pandemi Covid-19. Pembatasan gerak dan ruang memicu keterbatasan pedagang untuk bergerak di masa pandemi sehingga terjadinya penurunan omset penjulan pedagang sayur keliling. Dengan adanya permasalahan yang terjadi maka solusi yang ditawarkan yaitu memberikan arahan dan strategi peningkatan penjualan produk sayur melalui pemasaran online dan melakukan stategi promosi melalui sosial media. Hasil dari kegiatan penyuluhan ini dapat membantu meningkatkan pendapatan petani dan omset penjualan hingga 70%, pengemasan menjadi lebih baik, pemberian label jual, memiliki laporan keuangan dan penjualan produk melalui pemasaran online di Whatsapp Business
Perencanaan Rehabilitasi Drainase Ruas Jalan Telaga Warna Tlogomas Malang
Authors: Azwar Erizaldy , Pandulu Galih Damar , Primasworo Rifky Aldila , Sadillah M. , Rahma Pamela Dinar
Published: February 2023

The people of the Tlogomas sub-district, especially the residents of RT 07 RW 06, are facing the problem of rainwater inundation on the Telaga Warna road. Therefore the Tlogomas sub-district community needs competent personnel with Civil Engineering expertise and requires supporting equipment in terms of surveys and analysis equipment to plan drainage rehabilitation. This community service activity uses the AutoCAD program to apply topography measurement technology applications and drainage designs. The results of the topographic survey describe the longitudinal and transverse sections of the Telaga Warna road section. The cross-sectional design of the drainage channel using precast concrete/U-Gatter measuring 100x100 cm. From the calculation of the volume of drainage and rehabilitation needs for the Telaga Warna road section, a cost of Rp. 676,187,000,-. As a result of this community service activity, partners receive assistance in terms of planning so that a good and efficient implementation of the drainage rehabilitation plan is obtained.ABSTRAKMasyarakat kelurahan Tlogomas khususnya warga RT 07 RW 06 menghadapi permasalahan genangan air hujan di ruas jalan Telaga Warna. Oleh karena itu masyarakat kelurahan Tlogomas membutuhkan kompetensi personil yang mempunyai keahlian Teknik Sipil serta membutuhkan peralatan yang mendukung dalam hal survei maupun peralatan analisa untuk merencanakan rehabilitasi drainase. Tujuan dari kegiatan pengabdian kepada masyarakat ini adalah penerapan aplikasi teknologi pengukuran topografi serta desain drainase menggunakan program AutoCAD. Hasil survey topografi menggambarkan penampang memanjang dan melintang ruas jalan Telaga Warna. Serta desain penampang saluran drainase yang menggunakan beton precast/ U-Gatter ukuran 100x100 cm dari hasil perhitungan volume kebutuhan rehabilitasi drainase ruas jalan Telaga Warna dibutuhkan biaya sebesar Rp. 676.187.000,-. Hasil dari kegiatan pengabdian masyarakat ini, mitra memperoleh pendampingan dalam hal perencanaan sehingga diperoleh implementasi perencanaan rehabilitasi drainase yang baik dan efisien
Integrasi Teknologi Steam Sterilization dan Blancing Jamur Tiram Terolah Minimal dalam Mengatasi Over Stock saat Panen bagi UMKM di Kabupaten Malang
Authors: Ferdian Muh. Agus , Zairina Anisa , Rahardjo Poegoeh Prasetyo
Published: February 2023

This community service is carried out at the location of the oyster mushroom cultivation business in the District of Dau AR-5 RT. 02 RW. 10 District of Malang. Under these business conditions, many oyster mushroom products rot and are wasted during the main harvest, especially when demand for mushrooms falls, because oyster mushrooms have a short shelf life or are easily damaged quickly. In addition, the process of making baglog for oyster mushroom cultivation is carried out through the process stages. One of the main processes is sterilization/pasteurization, which requires a high cost. This phenomenon was experienced by CV. Tower two started the oyster mushroom cultivation business in 2011. The method that will be applied is the community empowerment method for the SME group to increase the productivity and independence of partners economically and socially through counseling and mentoring efforts. Assistance or introduction of tools in the form of sterilization equipment and boilers for the process of making baglog and technology for the production of blanching mushroom products. The service results provide benefits to partners' production to increase with a capacity of 500 baglogs used 4x a week. Based on these calculations, there is an increase in efficiency and turnover from partners.ABSTRAKPengabdian Masyarakat ini dilakukan dilokasi usaha budidya jamur tiram yang berada di Kecamatan Dau AR-5 RT. 02 RW. 10  Kabubaten Malang. Dengan kondisi usaha saat, terdapat banyak produk jamur tiram yang busuk dan terbuang saat panen raya terutama pada waktu permintaan jamur turun karena jamur tiram memiliki umur simpan yang pendek atau cepat mengalami kerusakan. Selain itu, proses pembuatan baglog jamur tiram yang dilakukan melalui beberapa tahapan proses salah satu proses utamanya adalah sterilisasi/pasteurisasi membutuhkan cost yang besar. Fenomena hal ini dialami oleh CV. Menara dua yang dimiliki oleh Bapak Azhal Alam Islamy yang memulai usaha budidaya jamur tiram dari tahun 2011 yang sampai saat ini masih belum menemukan formula yang tepat dalam mengatasi masalah tersebut. Metode yang akan diterapkan yaitu metode pemberdayaan masyarakat kelompok UKM dalam upaya peningkatan produktivitas dan kemandirian mitra secara ekonomi, sosial melalui usaha penyuluhan dan pendampingan. Bantuan ataupun perkenalan alat berupa alat seterilisasi dan boiler untuk proses pembuatan baglog serta teknologi produksi produk jamur blanching sangat membantu mereka dalam memajukan dan mengembangkan usaha.
Ahli Statistik Bola Basket dalam Pengembangan Sports Science
Authors: Mu'ammal Immanuel , Firmansyah Muhammad , Fuddin Muhammad Khoirul
Published: February 2023

Sports science is a factor that supports the sports industry. In basketball, game statistics are part of sports science. Basketball clubs in Malang need to become more familiar with match statistics, and the number of statisticians is insufficient. This community service aims to socialize and train human resources in several Malang city basketball clubs regarding game statistics. The activity is carried out in three stages: first, socialization of game statistics; second, training on the FIBA LiveStats application, third, Simulation of real games. The result of this activity is to create and form a community of basketball statisticians in Malang. This activity's existence impacts the recognition of basketball statistics, which will enhance the development of sports science. Actual experience in the field is needed to form a competent statistician, so further training is necessary.ABSTRAKSports science adalah faktor yang mampu mendukung industri olahraga. Dalam olahraga bola basket, statistik pertandingan adalah bagian dari sport science. Klub bola basket di kota Malang belum familiar dengan statistik pertandingan dan kuantitas ahli statistik belum memadai. Pengabdian masyarakat ini bertujuan untuk mensosialisasikan dan melatih sumber daya manusia di beberapa klub basket kota Malang mengenai statistik pertandingan. Pengabdian dilakukan melalui tiga tahap: pertama, sosialisasi statistik pertandingan, kedua, pelatihan aplikasi FIBA LiveStats, ketiga, Simulasi pada pertandingan. Hasil dari kegiatan ini adalah mencetak ahli statistik bola basket dan membentuk komunitas di kota Malang. Adanya kegiatan ini berdampak pada semakin dikenalnya statistik bola basket yang akan meningkatkan perkembangan sport science. Untuk membentuk ahli statistik yang kompeten maka diperlukan pengalaman nyata di lapangan maka pelatihan lanjutan perlu dilakukan.
Typical Cockpit Ergonomics Influence on Cervical Motor Control in Healthy Young Male Adults
Authors: Heggli Ursula , Swanenburg Jaap , Hofstetter Léonie , Häusler Melanie , Schweinhardt Petra , Bron Denis
Published: February 2023

INTRODUCTION: Neck pain and injury are common problems in military high-performance aircraft and helicopter aircrews. A contributing factor may be the reclined sitting position in cockpits. This study aimed to determine the effect of typical cockpit ergonomics on cervical proprioception,
assessed by using the cervical joint position error (cJPE).METHODS: A total of 49 healthy male military employees (mean age 19.9 ± 2.2 yr) were examined. Measurements of the cJPE were obtained in the flexion, extension, and rotation directions in an upright and in a 30°-reclined
sitting position. Each condition comprised three trials, with an additional 3-kg head load to mimic real world working conditions.RESULTS: A smaller cJPE was noted in the 30°-reclined sitting position (mean cJPE = 3.9 cm) than in the upright sitting position (mean cJPE = 4.6
cm) in the flexion direction. The cJPE decreased significantly in all movement directions across the three trials; for example, in the flexion direction in the 30°-reclined sitting position: Trial 1/2/3 mean cJPE = 5.0/3.8/3.1 cm.CONCLUSION: It seems that a reclined seating
position has a positive influence on cJPE. However, the result is weak. In both sitting positions and all three directions, the first tests of the cJPE showed the highest values. Already after one or two further measurement runs, a significantly reduced cJPE was observed. This rapid improvement
might indicate that an exercise similar to the cJPE test may improve the pilots' cervical proprioception and possibly reduce the risk of injury or pain.Heggli U, Swanenburg J, Hofstetter L, Häusler M, Schweinhardt P, Bron D. Typical cockpit ergonomics influence on cervical motor
control in healthy young male adults. Aerosp Med Hum Perform. 2023; 94(3):107–112.
Hypoxia Altitude Simulation and Reduction of Cerebral Oxygenation in COPD Patients
Authors: Dehe Lukas , Hohendanner Felix , Gültekin Emin , Werth Gordon , Wutzler Alexander , Bender Thorsten Onno
Published: February 2023

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is highly prevalent and often associated with chronic hypoxia. Previous studies have shown alterations of cerebral oxygenation and cardiac repolarization in COPD patients (GOLD stage II–IV). Airplane travel is common
in patients with COPD; however, the clinical effects of a diminished oxygen partial pressure in aircraft cabin environments at cruising altitude remain elusive. The aim of this study was to assess changes of cerebral oxygenation as well as parameters of cardiac repolarization during a hypoxia
altitude simulation combined with mild physical activity in these patients.METHODS: Patients with COPD and healthy subjects (10 per group) randomly selected from the Charité outpatient clinic conducted a hypoxia altitude simulation test which consisted of three phases. The
regional cerebral oxygen saturation (rSO2) of the frontal cortex was measured at rest using near-infrared spectroscopy (NIRS). Furthermore, oxygen saturation (SpO2), blood pressure, and heart rate values, as well as a 12-lead-ECG, were recorded. Subsequently,
a mild treadmill exercise program (25 W) was divided into 10 min of normoxia (pre-hypoxia), 30 min of mild hypoxia (FIO2 = 0.15), followed by a second 10-min period of normoxia (post-hypoxia). Meanwhile, mentioned parameters were recorded in 2-min intervals. P, PQ, QRS,
QT, QTc, QTd, T-peak-T-end interval (TpTe), and corrected TpTe (TpTec) were measured on three ECG complexes, each at baseline, at the end of the normoxic phase, and at the end of the hypoxic phase.RESULTS: A total of 10 patients with COPD and 10 control subjects were included in
this study. SpO2 was significantly lower in COPD patients throughout the whole test. Frontal cerebral rSO2 was significantly lower in the left hemisphere during hypoxia altitude simulation in COPD patients (59.5 ± 8.5 vs. 67.5 ± 5.7).CONCLUSIONS:
We show reduced left frontal cerebral oxygenation during hypoxia and mild exercise in patients with COPD, suggesting diminished altitude resilience and altitude capabilities. Preflight hypoxia assessment might be recommended to patients with severe COPD.Dehe L, Hohendanner F, Gültekin
E, Werth G, Wutzler A, Bender TO. Hypoxia altitude simulation and reduction of cerebral oxygenation in COPD patients. Aerosp Med Hum Perform. 2023; 94(3):102–106.
Extended Reality Applications for Space Health
Authors: Ebnali Mahdi , Paladugu Phani , Miccile Christian , Park Sandra Hyunsoo , Burian Barbara , Yule Steven , Dias Roger D.
Published: February 2023

INTRODUCTION: Spaceflight has detrimental effects on human health, imposing significant and unique risks to crewmembers due to physiological adaptations, exposure to physical and psychological stressors, and limited capabilities to provide medical care. Previous research has
proposed and evaluated several strategies to support and mitigate the risks related to astronauts' health and medical exploration capabilities. Among these, extended reality (XR) technologies, including augmented reality (AR), virtual reality (VR), and mixed reality (MR) have increasingly
been adopted for training, real-time clinical, and operational support in both terrestrial and aerospace settings, and only a few studies have reported research results on the applications of XR technologies for improving space health. This study aims to systematically review the scientific
literature that has explored the application of XR technologies in the space health field. We also discuss the methodological and design characteristics of the existing studies in this realm, informing future research and development efforts on applying XR technologies to improve space health
and enhance crew safety and performance.Ebnali M, Paladugu P, Miccile C, Park SH, Burian B, Yule S, Dias RD. Extended reality applications for space health. Aerosp Med Hum Perform. 2023; 94(3):122–130.
Lingering Altitude Effects During Piloting and Navigation in a Synthetic Cockpit
Authors: Beer Jeremy , Morse Bria , Dart Todd , Adler Samantha , Sherman Paul
Published: February 2023

INTRODUCTION: A study was performed to evaluate a cockpit flight simulation suite for measuring moderate altitude effects in a limited subject group. Objectives were to determine whether the apparatus can detect subtle deterioration, record physiological processes throughout
hypobaric exposure, and assess recovery.METHODS: Eight subjects trained to perform precision instrument control (PICT) flight and unusual attitude recovery (UAR) and completed chamber flights dedicated to the PICT and UAR, respectively. Each flight comprised five epochs, including
ground level pressure (GLP), ascent through altitude plateaus at 10,000, 14,000, and 17,500 ft (3050, 4270, and 5338 m), then postexposure recovery. PICT performance was assessed using control error (FSE) and time-out-of-bounds (TOOB) when pilots exited the flight corridor. UARs were assessed
using response times needed to initiate correction and to achieve wings-level attitude. Physiological indices included Spo2, heart rate (HR), end tidal O2 and CO2 pressures, and respiration metrics.RESULTS: Seven subjects completed both
flights. PICT performance deteriorated at altitude: FSE increased 33% at 17,513 ft and 21% in Recovery vs. GLP. Mean TOOB increased from 11 s at GLP to 60 s in Recovery. UAR effects were less clear, with some evidence of accelerated responses during and after ascent.CONCLUSIONS:
The test paradigm was shown to be effective; piloting impairment was detected during and after exposure. Physiological channels recorded a combination of hypoxia, elevated ventilation, and hypocapnia during ascent, followed by respiratory slowing in recovery. Findings indicate precision piloting
and respiration are subject to changes during moderate altitude exposure and may remain altered after Spo2 recovers, and changes may be linked to hypocapnia.Beer J, Morse B, Dart T, Adler S, Sherman P. Lingering altitude effects during piloting and navigation
in a synthetic cockpit. Aerosp Med Hum Perform. 2023; 94(3):135–141.
ATP binding by an F1Fo ATP synthase ε subunit is pH dependent, suggesting a diversity of ε subunit functional regulation in bacteria
Authors: Krah Alexander , Vogelaar Timothy , de Jong Sam I. , Claridge Jolyon K. , Bond Peter J. , McMillan Duncan G. G.
Published: February 2023

It is a conjecture that the ε subunit regulates ATP hydrolytic function of the F1Fo ATP synthase in bacteria. This has been proposed by the ε subunit taking an extended conformation, with a terminal helix probing into the central architecture of the hexameric catalytic domain, preventing ATP hydrolysis. The ε subunit takes a contracted conformation when bound to ATP, thus would not interfere with catalysis. A recent crystallographic study has disputed this; the Caldalkalibacillus thermarum TA2.A1 F1Fo ATP synthase cannot natively hydrolyse ATP, yet studies have demonstrated that the loss of the ε subunit terminal helix results in an ATP synthase capable of ATP hydrolysis, supporting ε subunit function. Analysis of sequence and crystallographic data of the C. thermarum F1Fo ATP synthase revealed two unique histidine residues. Molecular dynamics simulations suggested that the protonation state of these residues may influence ATP binding site stability. Yet these residues lie outside the ATP/Mg2+ binding site of the ε subunit. We then probed the effect of pH on the ATP binding affinity of the ε subunit from the C. thermarum F1Fo ATP synthase at various physiologically relevant pH values. We show that binding affinity changes 5.9 fold between pH 7.0, where binding is weakest, to pH 8.5 where it is strongest. Since the C. thermarum cytoplasm is pH 8.0 when it grows optimally, this correlates to the ε subunit being down due to ATP/Mg2+ affinity, and not being involved in blocking ATP hydrolysis. Here, we have experimentally correlated that the pH of the bacterial cytoplasm is of critical importance for ε subunit ATP affinity regulated by second-shell residues thus the function of the ε subunit changes with growth conditions.
Roles of lncRNAs in childhood cancer: Current landscape and future perspectives
Authors: Liu Fei , Xiong Qian-Wen , Wang Jin-Hu , Peng Wan-Xin
Published: February 2023

According to World Health Organization (WHO), cancer is the leading cause of death for children and adolescents. Leukemias, brain cancers, lymphomas and solid tumors, such as neuroblastoma, ostesarcoma and Wilms tumors are the most common types of childhood cancers. Approximately 400,000 children and adolescents between the ages of 0 and 19 are diagnosed with cancer each year worldwide. The cancer incidence rates have been rising for the past few decades. Generally, the prognosis of childhood cancers is favorable, but the survival rate for many unresectable or recurring cancers is substantially worse. Although random genetic mutations, persistent infections, and environmental factors may serve as contributing factors for many pediatric malignancies, the underlying mechanisms are yet unknown. Long non-coding RNAs (lncRNAs) are a group of transcripts with longer than 200 nucleotides that lack the coding capacity. However, increasing evidence indicates that lncRNAs play vital regulatory roles in cancer initiation and development in both adults and children. In particular, many lncRNAs are stable in cancer patients’ body fluids such as blood and urine, suggesting that they could be used as novel biomarkers. In support of this notion, lncRNAs have been identified in liquid biopsy samples from pediatric cancer patients. In this review, we look at the regulatory functions and underlying processes of lncRNAs in the initiation and progression of children cancer and discuss the potential of lncRNAs as biomarkers for early detection. We hope that this article will help researchers explore lncRNA functions and clinical applications in pediatric cancers.
Detection of peanut seed vigor based on hyperspectral imaging and chemometrics
Authors: Zou Zhiyong , Chen Jie , Wu Weijia , Luo Jinghao , Long Tao , Wu Qingsong , Wang Qianlong , Zhen Jiangbo , Zhao Yongpeng , Wang Yuchao , Chen Yongming , Zhou Man , Xu Lijia
Published: February 2023

Rapid nondestructive testing of peanut seed vigor is of great significance in current research. Before seeds are sown, effective screening of high-quality seeds for planting is crucial to improve the quality of crop yield, and seed vitality is one of the important indicators to evaluate seed quality, which can represent the potential ability of seeds to germinate quickly and whole and grow into normal seedlings or plants. Meanwhile, the advantage of nondestructive testing technology is that the seeds themselves will not be damaged. In this study, hyperspectral technology and superoxide dismutase activity were used to detect peanut seed vigor. To investigate peanut seed vigor and predict superoxide dismutase activity, spectral characteristics of peanut seeds in the wavelength range of 400-1000 nm were analyzed. The spectral data are processed by a variety of hot spot algorithms. Spectral data were preprocessed with Savitzky-Golay (SG), multivariate scatter correction (MSC), and median filtering (MF), which can effectively to reduce the effects of baseline drift and tilt. CatBoost and Gradient Boosted Decision Tree were used for feature band extraction, the top five weights of the characteristic bands of peanut seed vigor classification are 425.48nm, 930.8nm, 965.32nm, 984.0nm, and 994.7nm. XGBoost, LightGBM, Support Vector Machine and Random Forest were used for modeling of seed vitality classification. XGBoost and partial least squares regression were used to establish superoxide dismutase activity value regression model. The results indicated that MF-CatBoost-LightGBM was the best model for peanut seed vigor classification, and the accuracy result was 90.83%. MSC-CatBoost-PLSR was the optimal regression model of superoxide dismutase activity value. The results show that the R2 was 0.9787 and the RMSE value was 0.0566. The results suggested that hyperspectral technology could correlate the external manifestation of effective peanut seed vigor.
Sugemalimab plus chemotherapy vs. chemotherapy for metastatic non-small-cell lung cancer: A cost-effectiveness analysis
Authors: Liang Xueyan , Chen Xiaoyu , Li Huijuan , Liu Xiaoxia , Li Yan
Published: February 2023

Background

Sugemalimab is a newly developed inhibitor of programmed death ligand 1 (PD-L1). As a first-line treatment for metastatic non-small-cell lung cancer (NSCLC), sugemalimab plus chemotherapy (Sugema-Chemo) has been proven effective. Still, its cost-effectiveness has not yet been determined. The objective of this study was to assess the cost-effectiveness of Sugema-Chemo from a health care perspective in China.

Methods

A partitioned survival model was used. According to the GEMSTONE-302 trial, the clinical characteristics and outcomes of the patients were obtained. The outcomes were costs, quality-adjusted life-years (QALYs), incremental cost-effectiveness ratio (ICER), incremental net health benefits (INHB) and incremental net monetary benefits (INMB). The robustness of the model was further evaluated, as well as subgroup analyses. When the ICER was lower than the willingness to pay (WTP) threshold ($38,017/QALY or $86,376/QALY, defined as three times the per capita gross domestic product value of the general region and Beijing), the cost-effectiveness of Sugema-Chemo was assumed for general regions or Beijing.

Results

Compared with chemotherapy alone, Sugema-Chemo resulted in an incremental gain of 0.82 QALYs, an incremental gain of 1.26 life-years, as well as an average increase cost of $72,472. The ICER was $88,744/QALY. Model outcomes were susceptible to average body weight and cost of sugemalimab. Sugema-Chemo was cost-effective at a WTP threshold of 86,376/QALY if the average body weight was <62.44 kg or if the price of sugemalimab was <$2.996/mg. As well, Sugema-Chemo was also cost-effective when the cost of sugemalimab was <$1.839/mg for a WTP threshold of $38,017/QALY. Sugema-Chemo had a probability of > 50% being considered cost-effective in most subgroups at the $86,376/QALY threshold. However, Sugema-Chemo did not achieve cost-effectiveness (0%) in any of the subgroups when WTP was set at $38,017/QALY.

Conclusion

Sugema-Chemo might not be cost-effective in patients with metastatic NSCLC in China. In deciding between Sugema-Chemo and chemotherapy alone, it is essential to consider both the body weight of patients and the price of sugemalimab. A price reduction of sugemalimab under the National Healthcare Security Administration may be an effective measure to improve the cost-effectiveness of the drug.
Analytical Analysis of a Novel Flux Adjustable Permanent Magnet Eddy Current Coupling with Double-Sided Conductor
Authors: Kong Deshan , Wang Dazhi , Ni Yongliang , Song Keling , Qi Yufei , Li Yanming
Published: February 2023

The permanent magnet eddy current coupling is widely used in fan and pump equipment as an energy-saving speed control device. The traditional coupling speed adjustment method occupies too much axial space, limiting its application in the process of upgrading old equipment. This paper proposes a novel flux adjustable permanent magnet eddy current coupling with a double-sided conductor to reduce the coupling axial distance while increasing the coupling output torque. The relative angle between the permanent magnet rings is controlled to adjust the output torque, and the double-sided conductor structure is used to improve the output torque. The working principle of the proposed design is illustrated. An analytical model for estimating the regulation performance of the proposed structure is proposed, which introduces the regulated reluctance into the equivalent magnetic circuit method. Based on this model, the expressions for magnetic flux density, eddy current density, and output torque are established. Finally, the accuracy of the analytical model was verified by the 3D finite element method, and the parameter sensitivity analysis was performed. The analysis results show that this device can achieve a relatively large range of output torque regulation under the condition of a fixed air gap, and the output torque is greatly improved by adopting a double-sided conductor structure.
Women’s Risk-Taking Behaviour during COVID-19 Pandemic: Will Work–Family Enrichment and Work Satisfaction Prevent Turnover Intention?
Authors: Dewi I Gusti Ayu Manuati , Rajiani Ismi , Riana I Gede , Puspitawati Ni Made Dwi , Muafi Muafi , Rihayana I Gede
Published: February 2023

The COVID-19 pandemic has impacted all employment conditions as working during the pandemic is a risk to employees’ health. This study investigates women’s intentions to leave their job during times of crisis. However, opportunities for job selection were quite limited, and there are better ways to deal with job insecurity than leaving an organisation. The questionnaires were tested on valid data from 593 female employees of four-star hotels, and structural equation modelling (SEM) was employed. Cultural characteristics and the macroenvironment in Indonesian society cause different practices for women to achieve work–family enrichment, job satisfaction, and turnover intention than in developed Western cultures. Female employees will not be inclined to leave their job even though they are not satisfied. Moreover, work–family enrichment has an essential role in enhancing work satisfaction because it can improve women’s quality of life. Work–family enrichment was also found to reduce the intention of women to leave an organisation. However, work–family enrichment has a more substantial influence on intensifying work satisfaction than on deflating the choice to quit during a crisis. Therefore, the research findings revealed that work–family enrichment is essential in improving work satisfaction, increasing employees’ likelihood of remaining in the organisation. This study contributes to filling the research gap within work–family enrichment by digging into the practical lessons of women’s work behaviour in the service sector, specifically in the hotel industry.
Multi-Objective 3D Airspace Sectorization Problem Using NSGA-II with Prior Knowledge and External Archive
Authors: Zhang Weining , Hu Minghua , Yin Jianan , Li Haobin , Du Jinghan
Published: February 2023

Airspace sectorization is a powerful means to balance the increasing air traffic flow and limited airspace resources, which is related to the efficiency and safety of operations. In order to divide sectors reasonably, a multi-objective optimization framework for 3D airspace sectorization is proposed in this paper, including four core modules: Flight clustering, sector generation, workload evaluation, and sector optimization. Specifically, it clusters flights and generates initial sectors using a Voronoi diagram. To further optimize sector shape, the concept of dynamic density is introduced to evaluate the controller workload, based on which a sector optimization model is constructed. The model not only considers intra-sector and inter-sector workloads as objective functions but also sets hard constraints to meet operation and safety requirements. To solve it, a Non-dominated Sorting Genetic Algorithm II (NSGA-II) with prior knowledge and an external archive is designed. By analyzing the optimization results of actual operational data in the Singapore regional airspace, our approach obtains diverse optimal sectorization schemes for decision makers to choose from. Qualitative and quantitative experimental results confirm that the initial population strategy with prior knowledge significantly accelerates the convergence process. At the same time, the mechanism of the external archive effectively enriches the diversity of solutions.
A Method for Managing ADS-B Data Based on a 4D Airspace-Temporal Grid (GeoSOT-AS)
Authors: Deng Chen , Cheng Chengqi , Qu Tengteng , Li Shuang , Chen Bo
Published: February 2023

With the exponential increase in the volume of automatic dependent surveillance-broadcast (ADS-B), and other types of air traffic control (ATC) data containing spatiotemporal attributes, it remains uncertain how to respond to immediate ATC data access within a target area. Accordingly, an original multi-level disaggregated framework for airspace, and its corresponding information management is proposed. Further, a multi-scale grid modeling and coding mapping method of airspace information represented by ADS-B is put forth. Finally, tests on the validity of the 4D airspace-temporal grid we named as the GeoSOT-AS framework were conducted across key areas based on the development of an effective data organization method for ADS-B, or an effective algorithm for extracting relevant spatiotemporal data. Experimentally, it was demonstrated that GeoSOT-AS conforms to the existing Chinese specification of civil aeronautical charting and is advantageous for its low deformation and high practicality; furthermore, the airspace grid identification code modeling was less costly, and improved performance by >80% when used for ADS-B data extraction. GeoSOT-AS can thus provide effective reference and practical information for existing airspace data management methods represented by ADS-B and can subsequently be extended to other forms of airspace management scenarios.
Deep Reinforcement Learning-Based Failure-Safe Motion Planning for a 4-Wheeled 2-Steering Lunar Rover
Authors: Park Beom-Joon , Chung Hyun-Joon
Published: February 2023

The growing trend of onboard computational autonomy has increased the need for self-reliant rovers (SRRs) with high efficiency for unmanned rover activities. Mobility is directly associated with a successful execution mission, thus fault response for actuator failures is highly crucial for planetary exploration rovers in such a trend. However, most of the existing mobility health management systems for rovers have focused on fault diagnosis and protection sequences that are determined by human operators through ground-in-the-loop solutions. This paper presents a special four-wheeled two-steering lunar rover with a modified explicit steering mechanism, where each left and right wheel is controlled by only two actuators. Under these constraints, a new motion planning method that combines reinforcement learning with the rover’s kinematic model without the need for dynamics modeling is devised. A failure-safe algorithm is proposed to address the critical loss of mobility in the case of steering motor failure, by expanding the devised motion planning method, which is designed to ensure mobility for mission execution in a four-wheeled rover. The algorithm’s performance and applicability are validated through simulations on high-slip terrain scenarios caused by steering motor failure and compared with a conventional control method in terms of reliability. This simulation validation serves as a preliminary study toward future works on deformable terrain such as rough or soft areas and optimization of the deep neural network’s weight factor for fine-tuning in real experiments. The failure-safe motion planning provides valuable insights as a first-step approach toward developing autonomous recovery strategies for rover mobility.
End-to-End Optimization of Power-Limited Earth–Moon Trajectories
Authors: Petukhov Viacheslav , Yoon Sung Wook
Published: February 2023

The aim of this study is to analyze lunar trajectories with the optimal junction point of geocentric and selenocentric segments. The major motivation of this research is to answer two questions: (1) how much of the junction of the trajectory segments at the libration point between the Earth and the Moon is non-optimal? and (2) how much can the trajectory be improved by optimizing the junction point of the two segments? The formulation of the end-to-end optimization problem of power-limited trajectories to the Moon and a description of the method of its solution are given. The proposed method is based on the application of the maximum principle and continuation method. Canonical transformation is used to transform the costate variables between geocentric and selenocentric coordinate systems. For the initial guess, a collinear libration point between the Earth and the Moon is used as a junction point, and the transformation to the optimal junction of these segments is carried out using the continuation method. The developed approach does not require any user-supplied initial guesses. It provides the computation of the optimal transfer duration for trajectories with a given angular distance and facilitates the incorporation of the perturbing accelerations in the mathematical model. Numerical examples of low-thrust trajectories from an elliptical Earth orbit to a circular lunar orbit considering a four-body ephemeris model are given, and a comparison is made between the trajectories with an optimal junction point and the trajectories with a junction of geocentric and selenocentric segments at the libration point.
Can Agricultural Production Services Influence Smallholders’ Willingness to Adjust Their Agriculture Production Modes? Evidence from Rural China
Authors: He Yaping , Fu Dandan , Zhang Hua , Wang Xiudong
Published: February 2023

The transformation of agricultural production modes is an inevitable trend in China’s agricultural development. It is important to study the willingness of smallholder farmers to adjust their agricultural production modes to promote the transformation of China’s agricultural production modes. Agricultural production services are an effective way to realize the organic linkage between smallholder farmers and modern agriculture. To analyze the impact of agricultural production services on smallholder farmers’ willingness to adjust their agricultural production modes, this study uses data from a thematic study of 590 smallholder farmers in the Huang–Huai–Hai regions in 2022 to measure the extent of smallholder farmers’ full-cycle adoption of agricultural production services from the perspective of regional cropping systems for the first time and analyzes the impact of agricultural production services on farmers’ willingness to adjust their agricultural production modes. The study results show that the extent of full-cycle adoption of agricultural production services significantly affects farmers’ willingness to adjust their agricultural production modes. For each unit increase in the extent of full-cycle adoption of agricultural production services in line with the regional cropping system, the probability of farmers choosing “farmland transfer” and “agricultural production trusteeship” becomes 11.31 and 7.24 times higher than that of choosing “self-growing”, respectively. Based on the research results, this paper proposes the following countermeasures: first, we should pay more attention to the supply and demand of agricultural production services, especially to support the key weak links in developing agricultural production services for the process of grain production. Second, we should undertake more active and effective publicity measures to make full use of expressions that are acceptable to farmers to improve their understanding of productive agricultural services further and enhance their willingness to adopt productive agricultural services.
Effect of FASN, SCD, and GH Genes on Carcass Fatness and Fatty Acid Composition of Intramuscular Lipids in F1 Holstein × Beef Breeds
Authors: Pećina Mateja , Konjačić Miljenko , Ugarković Nikolina Kelava , Ivanković Ante
Published: February 2023

To improve beef quality, a selection of specific breeds for crossbreeding, genotyping, and selection of specific candidate genes in breeding animals can be some of the solutions. The objective of this study was to determine the effects of FASN, SCD, and GH genes on carcass fatness and fatty acid (FA) composition of intramuscular lipids of crossbred Holstein × beef breeds (Simmental, Belgian Blue, Limousin, and Piemontese). The allelic and genotypic distribution of polymorphisms in the FASN, SCD, and GH genes was studied in 80 crossbreed animals. Genomic DNA was isolated from musculus longissimus dorsi, whose chemical composition was determined by near infrared transmittance spectrophotometry, while the fatty acid composition was determined by gas chromatography. DNA polymorphism was analyzed by restriction fragment length polymorphism analysis. The FASN (g. 17924A>G) polymorphism was significantly associated with C19:1 n-9 and C24:1 n-9, whereas GH (g.2141C>G) was significantly associated with C16:0 and C20:1 n-9. The SCD (g.8586C>T) polymorphism was significantly associated with C16:0, C18:0, C20:0, C14:1 n-5, C16:1, C18:1, C18:2 n-6, C18:3 n-3, C20:2 n-6, and C20:4 n-6, and analyzed the sum and ratios of fatty acids. Sex had significant effect on carcass fatness and fatty acid composition. This study provided useful results for the above candidate genes and their association with some FA, supporting their influence as genes associated with fats and fatty acid composition in beef meat.
Ergot and Sterility in Bahiagrass: Genotypic and Environmental Effects on Seed Yield Potential
Authors: Do Canto Javier , Reyno Rafael , Oberti Hector , Dalla Rizza Marco , Real Daniel
Published: February 2023

Ergot disease (Claviceps paspali) and sterility have the potential to reduce seed yield in bahiagrass (Paspalum notatum Flüggé). Our objective was to determine the genotypic and environmental effects on seed yield, and the levels of ergot and sterility. Seventeen genotypes were evaluated in three locations across two years for seed yield, ergot severity, and total seed fractions (percentage of full seeds, ergot sclerotia and empty seeds). The percentage of full seeds and total seed yield were correlated (r = 0.52) but both were negatively correlated with the percentage of ergot sclerotia (r = −0.81 and −0.51). Empty seeds were negatively correlated with full seeds (r = −0.39), but not with ergot sclerotia and total seed yield. The genotype effect was significant for total seed yield and severity of infection with large heritabilities (H2 = 0.92 and 0.86) but had no effect on the percentage of the seed fractions. Location and the interaction with genotype explained most of the variation in the percentage of the seed fractions and their weight. Ergot and sterility were significant detrimental factors, genotype was a major determinant of ergot levels and seed yield, while non-genetic factors were co-determinants in constructing the seed yield potential but were the main determinants of the yield potential realization.
Multi-Trait Selection Index for Superior Agronomic and Tuber Quality Traits in Bush Yam (Dioscorea praehensilis Benth.)
Authors: Adewumi Adeyinka S. , Asare Paul A. , Adejumobi Idris I. , Adu Michael O. , Taah Kingsley J. , Adewale Samuel , Mondo Jean M. , Agre Paterne A.
Published: February 2023

Dioscorea praehensilis Benth. is a semi-wild yam species and a valuable source of resistance trait genes. To access the agronomic and tuber quality performance, eleven quantitative phenotypic traits were used to discriminate and identify promising accessions among 162 accessions of D. praehensilis collected in Ghana. Significant and high genetic variability (p < 0.001) for all eleven quantitative traits was found among the evaluated accessions. Moderate broad-sense heritability (H2) (30–60%) was observed for all the evaluated quantitative traits except the response to YMV and tuber hardness. The accessions were clustered into three groups; each cluster displayed genotypes with good potentiality for the different traits evaluated. Path coefficient analysis revealed positive contributions (p < 0.01) of the number of tubers per plant, tuber length, tuber width, stem internode length, number of internodes, and tuber flesh hardness to the total tuber weight per plant. Through the multi-trait genotype–ideotype distance index (MGIDI), 24 accessions were identified from the 162 evaluated accessions as top-ranking and could be used as progenitors for trait introgression. The results of this study provide insight for future yam breeding and improvement programs in West Africa.