bluuebunny/crossref_metadata_2025 huggingface dataset:
The Influence of Thyroid Hormone on Ca 2+ Signaling Pathways During Embryonal Development
Authors: Krebs Joachim
Published: June 2021

Thyroid hormones influence brain development through the regulation of gene expression.
Ca2+-dependent gene expression is a major pathway controlled by the Ca2+/calmodulin-dependent
protein kinase IV (CaMKIV), which in turn is induced by the thyroid hormone T3, as also demonstrated
in a mouse embryonic stem cell line. In addition, T3 controls the expression of
neurexin, synaptotagmin2 (SYT2), synaptotagmin-related gene1 (SRG1), and a number of other
genes involved in neurotransmitter release in a Ca2+-dependent manner. It has been noticed that the
development of dopaminergic neurons by evoking significant calcium entry occurs through TRPC
calcium channels. It was also demonstrated that the T3-mediated development of an early neuronal
network is characteristic for depolarizing GABAergic neurons concomitant with intracellular calcium
transients. An important aspect of T3-dependent regulation of gene expression in the developing
brain is its modulation by the transcription activator COUP-TF1. Regulation of alternative splicing
by CaMKIV is another important aspect for embryonal neural development since it can lead to
the expression of PMCA1a, the neuronal-specific isoform of the plasma membrane calcium pump.
Maternal hypothyroidism or CaMKIV deficiency can have a severe influence on fetal brain development.
Basal Cell Carcinoma Destruction by a Concentrate of Proteolytic Enzymes Enriched in Bromelain: A Preliminary Report
Authors: Rosenberg Lior , Singer Adam J , Shoham Yaron
Published: June 2021

Objectives:

Basal Cell Carcinoma (BCC) is the most common skin cancer generally treated by a variety of surgical and non-surgical destructive therapies. A Concentrate of Proteolytic Enzymes Enriched in Bromelain (CPEEB) derived from the stems of pineapples is approved for use for debriding deep burns. Prior studies suggest that bromelain also has anti-tumor effects. We describe our preliminary off-label treatment experience using topical CPEEB for the destruction of six BCCs in three patients.

Methods:

CPEEB was self-applied by three patients on six different Morphea, nodular, and superficially invasive BCCs. The CPEEB was applied as a thin layer prior to bedtime and left for a period of 9-12 hours. The wound was then covered with a petrolatum-based ointment for the next 24 hours. Application of the CPEEB was repeated up to 5 times over the course of 10 days, during which the patients were monitored daily and reevaluated by a board-certified plastic surgeon. If necessary, the CPEEB was reapplied up to five additional times over the next 10-day period. If necessary, any remaining lesion was surgically excised (MOHS surgery). The patients were then followed for up to 1 year.

Results:

Six BCCs located on the face, neck, and extremities were self-treated by three patients with 2-6 CPEEB applications. All of the BCCs were completely removed after the CPEEB application. CPEEB application was associated with local irritation and mild itching pain which resolved untreated within hours. In one patient, two of the lesion’s sites were surgically excised after 6 months with no tumor cells noted on histopathology. None of the BCCs recurred over the next 1 year.

Conclusion:

Our preliminary findings are a proof-of-concept that a concentrate of proteolytic enzymes enriched in bromelain may be a safe and effective destructive treatment for basal cell carcinomas. Future studies on larger groups of BCC patients are necessary in order to elucidate the potential use of CPEEB for this indication.
Scaphechinus mirabilis Extract Effectively Inhibits the Proliferation of
BPH-1 and LNCaP Prostate Epithelial Cells
Authors: Kim Kyung-Hyun , Hong Geum-Lan , Karunasagara Shanika , Jung Ju-Young
Published: June 2021

Background:

Benign Prostatic Hyperplasia (BPH) is an age-related disease characterized
by progressive proliferation of prostate stromal and epithelial cells. While the precise etiology
of BPH is still not clear, the proliferation of epithelial cells has been implicated in the development
of the disease. Scaphechinus mirabilis (S. mirabilis) is a marine species belonging to the order Clypeasteroida,
which contains flat, burrowing sea urchins.

Objective:

This study examined the effects of S. mirabilis extract on the proliferation of BPH-1 and
LNCaP prostate epithelial cells.

Methods:

BPH-1 and LNCaP cells were cultured and treated with S. mirabilis extract (50, 100, and
200 μg/ml). The viability of cells treated with S. mirabilis extract was determined by the MTT assay.

Results:

Proliferation of BPH-1 and testosterone-induced LNCaP cells was inhibited by treatment
with S. mirabilis extract. S. mirabilis extract suppressed the expression of androgen-related proteins,
such as androgen receptor, prostate-specific antigen, and 5α-reductase 2. S. mirabilis extract
inhibited testosterone-induced proliferation. Moreover, S. mirabilis extract induced apoptotic responses
by regulating the expression of caspase-9, Bcl-2, and Bax.

Conclusion:

These findings suggest that S. mirabilis extract abrogated the expression of androgen-
related proteins by inducing apoptotic responses, which could be valuable for the design of
new therapeutic agents for the treatment of BPH.
Alcohol and Psychosis: A Narrative Review of the Prevalence, Clinical Manifestations, and Management of Alcohol-related Psychotic Symptoms
Authors: Barrio Pablo , Seeman Mary V. , González-Rodríguez Alexandre
Published: June 2021

Background:

Alcohol use disorders, defined as the maintenance of alcohol use for at least a
12-month period despite negative psychological, biological, behavioral, and social consequences, are
frequently associated with psychotic symptoms.

Objective:

Our aim in this paper is to review alcohol-related clinical conditions that are accompanied
by psychotic symptoms, alcohol-induced psychotic disorder, alcohol withdrawal delirium, Wernicke’s
encephalopathy, Korsakoff’s dementia, comorbid schizophrenia, or delusional disorder.

Methods:

This is a non-systematic, narrative review based on the relevant literature indexed in
PubMed and Google Scholar databases [2000-2020].

Results:

Alcohol-induced psychotic disorder is characterized by the presence of auditory
hallucinations or delusions. In the state of alcohol withdrawal, tactile, visual hallucinations and
delusions are common. Wernicke-Korsakoff syndrome, caused by malnutrition secondary to chronic
alcohol misuse, is characterized by the presence of ataxia, ophthalmoplegia, and a range of mental
disturbances. The dual diagnosis of schizophrenia and alcohol use disorder rests on shared biological
impairments, as shown by neuroendocrinological and brain imaging studies. The subtype of the
delusional disorder called Othello’s syndrome, or delusional jealousy based on false beliefs of
infidelity, is often seen in the context of alcohol alone or alcohol and neurological disorder. Treatment
for alcoholic disorders with psychotic symptoms are dietary, psychological, and pharmacological.

Conclusions:

There are a number of alcohol-related psychotic syndromes, each requiring its own
specific treatment approach.
Kerentanan Spasial Air Tanah Terhadap Pencemaran Metode GOD Pada Formasi Batugamping Koral Kota Saumlaki, Maluku
Authors: Febriarta Erik , Prabawa Bayu Argadyanto , Larasati Ajeng
Published: June 2021

Kota Saumlaki merupakan ibu kota Kabupaten Maluku Tenggara Barat, yang secara geografis berada di ujung Pulau Yamdena bagian selatan dan merupakan bagian dari Pusat Kegiatan Strategis Nasional (PKSN) Saumlaki di Provinsi Maluku. Sebagai kawasan strategis Kota Saumlaki juga menjadi pusat pemerintahan dan memiliki laju pertumbuhan penduduk meningkat dan pembangunan yang semakin intensif. Dampak dari aktivitas tersebut dari ketersediaan sumber daya air (air baku) dapat mengalami defisit (kekurangan dalam mencukupi kebutuhan). Meningkatnya kebutuhan air baku dalam jumlah yang tinggi dapat mengakibatkan penurunan daya dukung sumber daya air secara kuantitas maupun kualitas. Penurunan kualitas air dapat ditimbulkan dari sisa hasil penggunaan air secara domsetik (rumah tangga), kegiatan perdagangan (kantor/pasar) maupun kegiatan industri. Menurunnya kualitas air tanah melebihi baku mutu air dapat mengakibatkan masalah kesehatan. Selain dari pengelolaan limbah air, pelu juga ditinjau dari sisi faktor lingkungan (geologi) dari sifat batuan terhadap kerentanan pencemaran. Untuk mengetahui hal tersebut maka tujuan dari penelitian ini adalah mengetahui potensi kerentanan air tanah terhadap pencemaran pada batugamping koral dengan pedekatan GOD di Kota Saumlaki. Kerentanan GOD didasarkan atas sifat batuan dalam meloloskan air tanah yaitu, tipe akuifer (G), litologi akuifer (O) dan kedalaman tinggi muka air (D). Berdasarkan hasil pengukuran diketahui di Kota Saumlaki dan sekitarnya terdapat dua (2) kelas, yaitu kerentanan tinggi dan kerentanan ekstrim. Pusat Kota Saumlaki termasuk kerentanan ekstrim yang dipengaruhi oleh kedalaman air tanah yang dangkal, dan sifat batuan yang porus dalam potensi mempercepat mengalirkan pencemaran.
Virtual fieldwork: inovasi pembelajaran aspek geografi fisik pasca pandemi COVID-19
Authors: Ashari Arif , Syarifudin Bagas , Wardoyo Muhammad Asrori Indra , Rosa Amalia Fadila , Kharisma Kharisma , Jamaludin Syarif
Published: June 2021

Pandemi global COVID-19 telah berdampak pada kehidupan penduduk dunia di 223 negara termasuk Indonesia. Sektor pendidikan merasakan dampak besar dengan ditutupnya banyak institusi pendidikan, sehingga pembelajaran harus dipindahkan ke dalam ruang virtual. Kondisi ini memberikan tantangan besar bagi pembelajaran geografi fisik yang membutuhkan penyampaian materi secara kontekstual didukung dengan studi lapangan. Artikel ini bertujuan untuk memberikan gagasan inovasi pembelajaran aspek geografi fisik di sekolah menengah maupun perguruan tinggi dengan sistem virtual fieldwork. Gagasan ini disertai dengan contoh implementasi yang telah dilakukan di Laboratorium Geografi Fisik UNY dalam pelaksanaan praktikum daring selama masa pandemi COVID-19 pada semester kedua 2020/2021. Virtual fieldwork dapat dilakukan melalui pembelajaran sikron tidak langsung atau dengan mengembangkan video pembelajaran yang didesain untuk memberikan visualisasi kondisi lapangan secara detail ke dalam ruang pembelajaran online. Penyajian video dan ruang lingkup materi perlu disesuaikan untuk mengakomodir kebutuhan ini. Inovasi pembelajaran semacam ini sangat diperlukan sebagai solusi pembelajaran daring pada masa pandemi dan juga tuntutan inovasi pembelajaran di Abad 21.
Identifikasi local climate zone dan sebaran spasial land surface temperature di Kota Semarang tahun 2019
Authors: Nucifera Fitria , Astuti Sola Tri
Published: June 2021

Urbanization in Indonesia has continued to increase starting in 2011. The increasing population impacted the conversion of agricultural land to non-agricultural land. Reduction in the proportion of green open space results in changes in the spatial pattern of the area which affects the increase in urban temperatures, thus triggering the occurrence of UHI. This study aims to determine the spatial distribution of LST and LCZ in Semarang City by using quantitative descriptive analysis. Semarang City has LST variation values between 24.72ºC to 32.56ºC. Semarang City has 13 types of LCZ, consisting of 6 LCZs based on building types and 7 LCZs based on land cover. LCZ type B is the largest LCZ which reaches 58.52 km² or 15.12% of the total area. The highest LST is LCZ type E, reaching 32.10 °C which displays rock landscapes or asphalt cover. The lowest value is LCZ type G, reaching 25.09°C, which is an open water body such as reservoirs and ponds. Climate-based urban planning can be carried out in the LCZ area which has a high temperature by observing and mitigating it through the constituent components of each LCZ.
Derecho y Medicina
Authors: Negrete Doria Eduar Felipe
Published: June 2021

El tema hace referencia a la responsabilidad médica y se desarrolla desde la perspectiva histórica hermenéutica del derecho clásico romano con base en la teoría jurídica de la argumentación de Alexis. Plantea la necesidad de estudios comparativos en derecho, como una forma de abordar fundamentos y criterios jurídicos transversales para confrontar su naturaleza. En él, se hace uso de principios jurídicos como el de la proporcionalidad, autorresponsabilidad, conducta humana, riesgo objetivo, ruptura del derecho y posición de garante entre otros para su desarrollo conceptual, especialmente en lo que corresponde a la evolución de la responsabilidad patrimonial partiendo del principio de la carga de la prueba   enfocado desde las obligaciones de medio y de resultado y considerando la tensión jurídica en las decisiones judiciales. Los diferentes criterios jurídicos se desarrollan con base en casos clásicos celebres del derecho romano que tratan diferentes eventos.
Language and Sentiment Regarding Telemedicine and COVID-19 on Twitter: Longitudinal Infodemiology Study
Authors: Pollack Catherine C , Gilbert-Diamond Diane , Alford-Teaster Jennifer A , Onega Tracy
Published: June 2021

Background

The COVID-19 pandemic has necessitated a rapid shift in how individuals interact with and receive fundamental services, including health care. Although telemedicine is not a novel technology, previous studies have offered mixed opinions surrounding its utilization. However, there exists a dearth of research on how these opinions have evolved over the course of the current pandemic.

Objective

This study aims to evaluate how the language and sentiment surrounding telemedicine has evolved throughout the COVID-19 pandemic.

Methods

Tweets published between January 1, 2020, and April 24, 2021, containing at least one telemedicine-related and one COVID-19–related search term (“telemedicine-COVID”) were collected from the Twitter full archive search (N=351,718). A comparator sample containing only COVID-19 terms (“general-COVID”) was collected and sampled based on the daily distribution of telemedicine-COVID tweets. In addition to analyses of retweets and favorites, sentiment analysis was performed on both data sets in aggregate and within a subset of tweets receiving the top 100 most and least retweets.

Results

Telemedicine gained prominence during the early stages of the pandemic (ie, March through May 2020) before leveling off and reaching a steady state from June 2020 onward. Telemedicine-COVID tweets had a 21% lower average number of retweets than general-COVID tweets (incidence rate ratio 0.79, 95% CI 0.63-0.99; P=.04), but there was no difference in favorites. A majority of telemedicine-COVID tweets (180,295/351,718, 51.3%) were characterized as “positive,” compared to only 38.5% (135,434/351,401) of general-COVID tweets (P<.001). This trend was also true on a monthly level from March 2020 through April 2021. The most retweeted posts in both telemedicine-COVID and general-COVID data sets were authored by journalists and politicians. Whereas the majority of the most retweeted posts within the telemedicine-COVID data set were positive (55/101, 54.5%), a plurality of the most retweeted posts within the general-COVID data set were negative (44/89, 49.4%; P=.01).

Conclusions

During the COVID-19 pandemic, opinions surrounding telemedicine evolved to become more positive, especially when compared to the larger pool of COVID-19–related tweets. Decision makers should capitalize on these shifting public opinions to invest in telemedicine infrastructure and ensure its accessibility and success in a postpandemic world.
Smartloss: A Personalized Mobile Health Intervention for Weight Management and Health Promotion
Authors: Martin Corby K , Gilmore L. Anne , Apolzan John W , Myers Candice A , Thomas Diana M , Redman Leanne M
Published: June 2021

Background

Synonymous with increased use of mobile phones has been the development of mobile health (mHealth) technology for improving health, including weight management. Behavior change theory (eg, the theory of planned behavior) can be effectively encapsulated into mobile phone-based health improvement programs, which is fostered by the ability of mobile phones and related devices to collect and transmit objective data in near real time and for health care or research professionals and clients to communicate easily.

Objective

To describe SmartLoss, a semiautomated mHealth platform for weight loss.

Methods

We developed and validated a dynamic energy balance model that determines the amount of weight an individual will lose over time if they are adherent to an energy intake prescription. This model was incorporated into computer code that enables adherence to a prescribed caloric prescription determined from the change in body weight of the individual. Data from the individual are then used to guide personalized recommendations regarding weight loss and behavior change via a semiautomated mHealth platform called SmartLoss, which consists of 2 elements: (1) a clinician dashboard and (2) a mobile phone app. SmartLoss includes and interfaces with a network-connected bathroom scale and a Bluetooth-connected accelerometer, which enables automated collection of client information (eg, body weight change and physical activity patterns), as well as the systematic delivery of preplanned health materials and automated feedback that is based on client data and is designed to foster prolonged adherence with body weight, diet, and exercise goals. The clinician dashboard allows for efficient remote monitoring of all clients simultaneously, which may further increase adherence, personalization of treatment, treatment fidelity, and efficacy.

Results

Evidence of the efficacy of the SmartLoss approach has been reported previously. The present report provides a thorough description of the SmartLoss Virtual Weight Management Suite, a professionally programmed platform that facilitates treatment fidelity and the ability to customize interventions and disseminate them widely.

Conclusions

SmartLoss functions as a virtual weight management clinic that relies upon empirical weight loss research and behavioral theory to promote behavior change and weight loss.
Sequential Data–Based Patient Similarity Framework for Patient Outcome Prediction: Algorithm Development (Preprint)
Authors: Wang Ni , Wang Muyu , Zhou Yang , Liu Honglei , Wei Lan , Fei Xiaolu , Chen Hui
Published: June 2021

BACKGROUND

Sequential information in electronic medical records is valuable and helpful for patient outcome prediction but is rarely used for patient similarity measurement because of its unevenness, irregularity, and heterogeneity.

OBJECTIVE

We aimed to develop a patient similarity framework for patient outcome prediction that makes use of sequential and cross-sectional information in electronic medical record systems.

METHODS

Sequence similarity was calculated from timestamped event sequences using edit distance, and trend similarity was calculated from time series using dynamic time warping and Haar decomposition. We also extracted cross-sectional information, namely, demographic, laboratory test, and radiological report data, for additional similarity calculations. We validated the effectiveness of the framework by constructing k–nearest neighbors classifiers to predict mortality and readmission for acute myocardial infarction patients, using data from (1) a public data set and (2) a private data set, at 3 time points—at admission, on Day 7, and at discharge—to provide early warning patient outcomes. We also constructed state-of-the-art Euclidean-distance k–nearest neighbor, logistic regression, random forest, long short-term memory network, and recurrent neural network models, which were used for comparison.

RESULTS

With all available information during a hospitalization episode, predictive models using the similarity model outperformed baseline models based on both public and private data sets. For mortality predictions, all models except for the logistic regression model showed improved performances over time. There were no such increasing trends in predictive performances for readmission predictions. The random forest and logistic regression models performed best for mortality and readmission predictions, respectively, when using information from the first week after admission.

CONCLUSIONS

For patient outcome predictions, the patient similarity framework facilitated sequential similarity calculations for uneven electronic medical record data and helped improve predictive performance.
Body Weight Gain and Carcass Quality of the Hybrid Chicken Derived from the Crossing between Female F1 Kampung Super and Male F1 Kampung-Broiler
Authors: Puspita Utin Elsya , Saragih Hendry T.S.S.G. , Hartatik Tety , Daryono Budi Setiadi
Published: June 2021

This research was conducted to observe the body weight gain and carcass quality of the hybrid chicken derived from the crossing between female F1 Kampung Super and male F1 Kampung-Broiler. The weekly weight gain for seven weeks and carcass quality, including breast yield, protein content, lipid content, moisture, and pH were measured with each group consists of six individuals. The chickens were slaughtered for meat quality measurements on the 7th week. The results showed that the hybrid chickens’ weight at the 7th week (888.22±139.63) was higher than layer (467.06±85.7) and pelung (436.39±42.33). The hybrid chicken’s breast yield (3.20%) was significantly higher than pelung’s (1.66%). These characteristics of hybrid chicken breast muscle lead to the conclusion that hybrid chicken is a potential alternative meat-type chicken with local chicken meat characteristics and has relatively fast growth.
What works when: mapping patient and stakeholder engagement methods along the ten-step continuum framework
Authors: Edwards Hillary A , Huang Jennifer , Jansky Liz , Mullins CD
Published: June 2021

Aim:This study provides a recommended ‘patient engagement translation table’ that identifies evidence-based methods for meaningful patient engagement along a ten-step framework for continuous engagement.Materials & methods:We used a mixed methods research design to collect data on preferred engagement methods, including an environmental scan of available literature, interviews and focus groups with patient-centered outcomes research stakeholders to match methods with research steps and a modified Delphi process with subject matter experts to create the final translation table.Results:Evidence-based engagement methods included community partnerships, focus groups, interviews, meetings, sharing print materials, social media, storytelling, surveys and including patients as research team members.Conclusion:Our recommended patient engagement translation table is designed to assist investigators in determining appropriate engagement methods for meaningful interactions with stakeholders.
Injusticias en los campos artísticos: el caso de directoras teatrales contemporáneas en Córdoba, Argentina
Authors: Marin Fwala-lo
Published: June 2021

Problematizamos desigualdades de género en torno a premios en el teatro independiente de Córdoba (Argentina), con el propósito de entender las lógicas de reconocimiento en un asimétrico mundo del arte. Para ello, revisamos teóricamente los criterios de distinción desde la perspectiva de género, considerando aspectos estéticos y extra estéticos de las obras, así como la noción de genio, asociada históricamente con el rol de la dirección. Además, analizamos los reconocimientos y auto reconocimientos de mujeres y disidencias en roles directoriales. Luego, atendemos a las esferas pública y privada como ordenadoras de las prácticas teatrales. En particular, abordamos el caso de los Premios Provinciales de Teatro; incluimos datos estadísticos, sistematizamos las repercusiones de la edición 2019 y confrontamos posturas sobre posibles soluciones afirmativas o transformativas en torno a las injusticias de reconocimiento.
Palabras clave: Artes dramáticas; Igualdad de género; Estética; Distinción público y privado; Dirección teatral
El movimiento para la Liberación de la Mujer en Costa Rica (1975-1981)
Authors: Quesada Alexia Ugalde
Published: June 2021

Este artículo recupera la historia de la primera agrupación de la segunda ola feminista en Costa Rica, el Movimiento para la Liberación de la Mujer (MLM). Con el objetivo de comprender cuáles ideas y debates introdujo en el país, se analizan sus discursos publicados en Qué hacer?, un periódico de la Organización Socialista de los Trabajadores (OST), primer partido trostskista costarricense. Se concluye que el MLM posicionó la discusión sobre los derechos reproductivos de las mujeres y la doble jornada laboral, gracias a un análisis de la realidad nacional que vinculó el feminismo radical con el marxismo.

Palabras clave: Historia; Segunda ola del feminismo; Doble militancia; Trotskismo; Derechos reproductivos; Planificación familiar
Social Development in Sungai Kakap Village (Study on Social Change and Development)
Authors: Ramadhan Iwan , Daniel Daniel
Published: June 2021

The problems that often arise in village development are the low of welfare and quality of people’s life in the village; lack of desire of the stakeholders to accelerate the development itself; as well as village governance that requires adjustment to the mandate of Law Number 14 of 2014 concerning Villages. Therefore, village development needs to have proper planning and management, so the village can be developed properly. In this case, there is a need for sustainable planning and development that fit of planning and programs that have been prepared in order to optimize the potential of natural resources, human resources, and science and technology. By matching and combining the three components, it is hoped that these three aspects can run well. and can be sustainable. The method used in this research was descriptive qualitative research method. The expected objectives of this research were to find out the existing development programs in Sungai Kakap village, investigate what facilities are available there, and community empowerment programs implemented. It was also to find out the social changes that have occurred in Sungai Kakap village due to the development that occurred there.
SOSIAL EKONOMI PEREMPUAN MIGRAN KEMBALI (RETURN MIGRANT) JORONG KAPUH, NAGARI SUMANI, KAB. SOLOK
Authors: Nengrum Yuliana , Yulkardi Yulkardi , Rahmad Darmairal
Published: June 2021

Marantau is a tradition in Minangkabaunes. Such as with Jorong Kapuh society it is economic factor and behavior as support their to do it. In the bight economic factor homogeny and less economic to get daily want until 70% in that condition. The aims based on resolution of the problem are: first, to describe a woman knowledge about bight, second, to describe the reason a woman can do it, third, to describe the reason a woman as a brighter and return migrant, fourth, to describe economic social condition us return migrant. Research counducted with qualitative approach with descriptive method. Informant chosed using purposive. The result of this research conclusion of bight woman is studied, couple research, socialization with another society. Social economic condition have two differences variable, first, economic variable (their physic necessity, health for economic physic), second, social variable (long life need, the appreciate of society, help another, success in their life).Merantau merupakan tradisi masyarakat Minangkabau. Demikian halnya dengan masyarakat Jorong Kapuh, selain dari merantau menjadi suatu tradisi faktor ekonomi dan keadaan alam juga sebagai pendorong bagi masyarakat Jorong Kapuh untuk merantau. Berdasarkan rumusan masalah terdapat empat tujuan penelitian yaitu: pertama, mendeskripsikan pengetahuan perempuan tentang merantau, kedua, mendeskripsikan alasan perempuan merantau, ketiga, mendeskripsikan alasan perempuanperantau, kembali kekampunghalamannya, keempat, mendeskripsikan kondisi sosiale konomi perempuan perantau pasca migrasi sebagai migrant kembali. Penelitian dilakukan dengan pendekatan kualitatif dengan metode penelitian deskriptif. Teknik pengambilan informan dilakukan dengancara purposive sampling. Hasil dari penelitian ini, dapat disimpulkan bahwa perempuan merantau yaitu mencari pengalaman hidup, perubahan ekonomi yang lebih baik, mencari jodoh, menuntut ilmu, bersosialisasi dengan masyarakat di rantau. Kondisi sosial ekonomi perempuan perantau migrant kembali dibedakan dua yaitu: pertama, ekonomi (berupa kebutuhan dasar berupa sandang, pangan, papan, kesehatan, terpenuhinya kebutuhan ekonomi). Kedua, secara sosial (berupa terpenuhinya kebutuhan hidup, saling bekerjasama, penghargaan yang di berikan oleh masyarakat, keberhasilan perubahan hidup yang dicapai)
Front Matter Jurnal Ilmu Sosial Mamangan
Authors: Admin Admin
Published: June 2021

..
Evaluation of Government Policy in Development of Pentadio Resort in Gorontalo
Authors: Mohi Widya Kurniati , Akbar Muh Firyal , One Astin Yasin
Published: June 2021

The development of tourism object of Pentadio resort in Gorontalo is required in order to increase the benefit to tourism object especially economic value. In fact, these expectations have not been supported by the Local Government. This research aims to obtain information on government policy evaluation in the development of tourism object of Pentadio Resort in Gorontalo, by using a theory of policy evaluation. The research method used a qualitative approach with case study research, while the data were collected from in-depth interviews with informants. Data were also collected from participant observations and recording of secondary data related to the research problem. The results of this study evaluate the policy undertaken in the development of Pentadio Resort. It has not been maximally shown by five indicators of policy evaluation by William N. Dunn. There are still obstacles encountered in the implementation of a policy. So the recommendations in this article are expected to optimize the implementation of policy evaluations that have been made, in order to take a policy that serves as a benchmark of success in the development of a tourism development. One of consideration in the Pentadio Resort development of a tourist attraction is the possibility of management of tourism by private parties
Social Rehabilitation Constraintsin Children Facing the Laws Management
Authors: Ningrum Prike , Elfitra Elfitra , Alfiandi Bob
Published: June 2021

Program rehabilitasi sosial Anak Berhadapan dengan Hukum (ABH) merupakan upaya pemerintah untuk pemenuhan hak-hak dasar ABH selama di Lembaga Penyelenggaraan Kesejahteraan Sosial yaitu Panti Sosial Asuhan Anak Bina Remaja Budi Utama. Terdapat kendala PSAABR melaksanakan rehabilitasi sosial ABH. Tujuan dari penelitian ini adalah untuk mengetahui kendala-kendala apa yang dialami oleh PSAABR dalam rehabilitasi sosial ABH. Teori yang digunakan adalah teori strukturasi yang dipelopori oleh Anthony Giddens yang memfokuskan pada hubungan dualitas antara agen dan struktur. Penelitian dilakukan dengan pendekatan hermeneutika ganda sebagai salah satu sub tipe riset kualitatif. Artikel ini akan menunjukkan bahwa kendala-kendala yang dihadapi pengelola PSAABR dalam rehabilitasi sosial ABH adalah kurangnya sumber daya manusia, minimnya anggaran dana untuk ABH, sarana dan prasarana yang kurang memadai, serta kurangnya pemahaman pengelola terkait metode penanganan ABH.Kata kunci: Anak,  Hukum, Rehabilitasi, Sosial
The Role of Forsis LSM (Fort De Kock Society in Social) for Reach The Risk Groups of HIV / AIDS (Case Study: LGBT And Penasun Group�s in The City of Padang)
Authors: Yanti Anggun Mustika , Yuhelna Yuhelna , Fitlayeni Rinel
Published: June 2021

One of the existing NGOs is FORSIS which is engaged in the grouping of HIV / AIDS risk groups to cope with the spread of HIV / AIDS in the city of Padang. The purpose of this study is to describe how the role of FORSIS in outreach groups at risk of HIV / AIDS in the city of Padang. The approach used in this research is a qualitative descriptive researcher, a technique used for data collection in interviews, observations, and document studies. In addition to the selection of informants is purposive sampling, which consists of informants who are considered to know about the role of FORSIS in outreach groups at risk of HIV / AIDS. The subjects in this research are Padang city community that is the board of FORSIS, LGBT group, caretaker of soul conscience, and LGBT with HIV. The results of this study are to describe the role of FORSIS in outreach groups at risk of HIV / AIDS. Prior to outreach there was a process planned for outreach. This NGO plays a role in improving community knowledge through socialization, then invites VCT to know the status of self so that can cope with the spread of viruses and NGOs also do cooperation with NGOs taratak soul heart to accompany PLWHA. It can be concluded that this FORSIS NGO plays an important role in providing counselling, inviting VCT and working with specific NGOs to assist in the prevention and transmission of HIV / AIDS.
Using virtual reality technologies to visualize parameters of urban microclimate
Authors: Olenkov Valentin D. , Biryukov Aleksandr D. , Alena O. Kolmogorova
Published: June 2021

Abstract Introduction. Methods of computational fluid dynamics (CFD) are widely used in architecture and civil engineering to study the microclimate of a city or simulate the wind regime of a building. Using virtual reality (VR) technologies to assess local airflow parameters in respect of an individual can significantly increase the informativity of the microclimate simulation. The process of simulation and post-processing of hydrodynamic simulation problems in classical CAE (computer-aided engineering) packages is difficult for non-professional researchers and does not provide a flexible interaction mechanism for specialists in the remote work environment. The solution is to develop an external universal post-processor supporting modern technologies of virtual reality and network interaction. Materials and methods. A model of an airflow around a group of buildings was used as the test data, and the results were exported to an external visualizer. The solution employs the Unity3D engine, and the Ansys Fluent package is used as the data source. Results. The paper describes the general architecture and implementation details of the PLT-Sim prototype, which includes basic tools for interactive visualization of vector airflow data in the virtual reality mode, as well as the system designated for importing results from different modeling systems. The stereoscopic representation of the image of airflow velocities makes it possible to implement new mechanics of interaction with computer models from the point of view of pedestrians. Conclusions. Using new methods of VR visualization of experiments in the real time makes it possible to more accurately substantiate the results of research activities. The proposed solution will allow to predict and detect design errors, as well as facilitate remote collaboration between researchers focused on research tasks in the context of a pandemic. This software and hardware solution is one of the first prototypes that implements an approach to visualizing microclimate and wind comfort data as viewed by an individual pedestrian.
A research into the development of models of random variables as part of the structural reliability analysis performed in the absence of some statistical information
Authors: Soloveva Anastasia A. , Solovev Sergey A.
Published: June 2021

Introduction. The scientific review article addresses the approaches to the modeling of random variables performed as part of the structural reliability analysis of elements provided that some statistical information missing (limited). The objectives of the research include the statement of the problem of the probabilistic structural reliability analysis subject to incomplete statistical data, the study of the development of approaches to the generation of models of random variables within the framework of this problem, as well as the assessment of the current state of affairs in this field and some development prospects for the coming years.

Materials and methods. The principal model of a random variable, considered in the article, represents a p-box (pro­bability box) model. A p-box is an area of possible functions of distributed probabilities of a random variable generated by the two boundary functions of the probability distribution. The article addresses p-boxes generated using the fuzzy set theory, the probability theory, Kolmogorov–Smirnov boundaries, etc.

Results. The approaches, considered in the article, are illustrated by the numerical examples of p-boxes that use the same statistical data. P-boxes, based on the probability theory, allow to accurately simulate a random variable; however, a priori information about the type of the distribution function is needed. P-boxes, based on the possibility theory, can be used even if an extremely small amount of statistical data is available, and it is also necessary to carefully address the issue of assigning the cutoff (risk) level. P-boxes based on the Chebyshev inequality and the Kolmogorov–Smirnov statistics allow to effectively simulate random variables regardless of the type of the probability distribution. However, these approaches may generate an assessment that is too uninformative for decisions to be made in a number of tasks.

Conclusions. The choice of a probabilistic model of a random variable for the further reliability analysis of structural elements will depend on the amount and type of statistical data obtained about the random variable. In particular cases, if the statistical information represents a subset of intervals, special approaches based on the Dempster–Shafer theory can be used. A promising and relevant method that underlies both the development of probabilistic models of random variables and the analysis of structural reliability in case of missing statistical information encompasses the employment of numerical modeling methods that employ surrogate models (kriging, Bayesian networks, interval predictors, etc.) and neural network algorithms.
a×b=c in 2+1D TQFT
Authors: Buican Matthew , Li Linfeng , Radhakrishnan Rajath
Published: June 2021

We study the implications of the anyon fusion equation a×b=c on global properties of 2+1D topological quantum field theories (TQFTs). Here a and b are anyons that fuse together to give a unique anyon, c. As is well known, when at least one of a and b is abelian, such equations describe aspects of the one-form symmetry of the theory. When a and b are non-abelian, the most obvious way such fusions arise is when a TQFT can be resolved into a product of TQFTs with trivial mutual braiding, and a and b lie in separate factors. More generally, we argue that the appearance of such fusions for non-abelian a and b can also be an indication of zero-form symmetries in a TQFT, of what we term "quasi-zero-form symmetries" (as in the case of discrete gauge theories based on the largest Mathieu group, M24), or of the existence of non-modular fusion subcategories. We study these ideas in a variety of TQFT settings from (twisted and untwisted) discrete gauge theories to Chern-Simons theories based on continuous gauge groups and related cosets. Along the way, we prove various useful theorems.
State-Confessional Relations Modern Classifications Analysis
Authors:   Office of the Ombudsman for Human Rights in the Russian Federation, Shikher N.D.
Published: June 2021

The typologies of relations between the state and religious associations existing in the scientific doctrine, are considered. Based on a systematic analysis, the typologies are grouped according to the complexity of the internal structure and analyzed for universality of application. The author has proposed a new classification of state-confessional relations models which most fully reflects the realities of the modern world.
Demarcation of Legislative Powers between the Chambers of the Bicameral Russian Parliament in the Context of Foreign Experience
Authors:   Russian Presidential Academy of National Economy and Public Administration, Chervinskaya A.P.
Published: June 2021

Demarcation of legislative competence of the chambers of the Federal Assembly of the Russian Federation: the State Duma and the Federation Council, is studied. It is concluded that the actual powers of the Federation Council in the legislative process are significantly inferior to the real competence of the State Duma. The experience of foreign countries in the demarcation of legislative competence between the chambers of bicameral parliaments is studied.
New Federal Law as the Completion of the Youth Policy Constitutionalization Process in the Russian Federation
Authors:   Russian Presidential Academy of National Economy and Public Administration, Merkulov P.A.
Published: June 2021

The final stage of the process of constitutionalization of youth policy in modern Russia is analyzed. Based on the results of the analysis, the author expresses a scientifically reasoned point of view on the key provisions of the new law, concluding that the constitutionalization of youth policy has been completed and that it is important to adopt the new law in terms of creating regulatory and legal conditions for the effective implementation of youth policy in Russia.
Territorial Autonomies in Unitary States in the Post-Soviet Space: Devolution of Legislative Powers
Authors:   Kazan (Volga Region) Federal University, Nazaretyan D.G.
Published: June 2021

A comparative legal analysis of the legislative powers of territorial autonomies in the form of republics in post-Soviet countries is drawn. On the basis of constitutional legal acts, the presence or absence of certain signs of statehood in the autonomies under consideration, as well as their relationship with the central authorities of the countries they are part of, are analyzed.
Legal Regulation of Public Relations in the Context of Digitalization: Institutions and the Institutional Environment
Authors:   Russian Presidential Academy of National Economy and Public Administration, Bryantsev I.I. , Bryantseva O.V. ,   Saratov State Academy of Law
Published: June 2021

An overview of information and communication practices affecting the formation of public relations in the state and determining the institutional environment is presented. It is noted that the actual task of the state in these conditions becomes the management of a structured system of social relations, formed on the basis of communication relationships between various subjects of civil society, business and citizens.
Russian Legislation Development in Conditions of COVID -19
Authors:   Saratov State Academy of Law, Arkhipova E.Yu.
Published: June 2021

The main trends typical for the current Russian legislation system are considered. Traditional or constant trends and new ones conditioned by a number of external and internal factors are distinguished. To the external factors in particular, the author refers the spread of coronavirus pandemic, which actualized the development of cyclic legislation as well as the digitalization of law.
Implementing the Principle of Legality in Improving Educational Organizations Territories
Authors:   Saratov State Academy of Law, Ivanov A.A. , Kondrashov Yu.A. ,   Saratov State Academy of Law
Published: June 2021

Issues of legality of using students’, their legal representatives and teachers’ labor on the territory of schools from the point of view of Russian and international legislation are considered. The article analyzes the issues related to involving students (and their parents) in the activities aimed at improving the territory and premises of an educational institutions from the point of view of the federal law “On Environmental Protection” and bylaws and instilling socially significant qualities in the younger generation.
Forecasting Activities Reflective Function in a Systemic Crisis
Authors:   Russian Presidential Academy of National Economy and Public Administration, Cheremnykh V.Yu. , Yakovlev L.S. ,   Russian Presidential Academy of National Economy and Public Administration
Published: June 2021

Issues of the predictive activity methodology regarding changes in self-identification practices of societies are analyzed. A genetic approach to understanding the logic of the development of strategies for developing forecasts is implemented. Types of strategies inherent in traditional, industrial, and post-industrial societies are identified. The conclusion about the necessity of transition to a methodology based on the articulation of dynamic processes, rather than static states, in forecasting activities is substantiated.
Social Accountability and Graduate Medical Education
Authors: Kaufman Arthur , Scott Mary Alice , Andazola John , Fitzsimmons-Pattison Danielle , Parajón Laura
Published: June 2021

Because graduate medical education (GME) is largely publicly funded, it should be judged on how well it addresses the public’s health needs. However, the current system distributes GME resources inequitably by specialty and geography, and neglects to focus on training physicians adequately in the care of populations while reducing health disparities. Instead, GME continues to concentrate training in hospital-based academic centers and in subspecialties, which often exacerbates disparities in health outcomes and access to care. GME can be more socially accountable by shifting incentive structures to support primary care, creating more equitable distribution of residency slots and funding, and promoting training programs that focus on social and structural determinants of health.
Common diseases of snap bean (phaseolus vulgaris l.) for biological production
Authors:   Maritsa Vegetable Crops Research Institute (MVCRI) – Plovdiv, Georgieva Olga , Karadzhova Natalia ,   Maritsa Vegetable Crops Research Institute (MVCRI) – Plovdiv
Published: June 2021

The main diseases of snap bean (Phaseolus vulgaris L.) for organic production and the possibilities for control have been studied. The strategic directions of the experimental work included: monitoring of diseases; study of pathogens’ variability; the field resistance of the Bulgarian bean varieties “Evros” and “Tangra” to the diseases in organic farming; optimization of the phytosanitary state of the crop through the authorized plant protection products. It has been established that seed-borne diseases are of predominant importance for organically grown garden beans. These are bacterial blight Xantomonas axanopodis pv. phaseoli, halo blight Pseudomonas syringae pv. phaseolicola and anthracnose Colletotrichum lindemuthianum. The screening of Bulgarian bean varieties for disease resistance showed that the “Evros” variety is relatively resistant to bacterial blight and anthracnose, which makes it suitable for growing by biological technologies. The development of bacterial blight and anthracnose after five treatments with the fungicide Bordeaux Mix 20VP (Bordeaux mixture 200 g/kg Cu +) with an interval of 10-14 days, starting from the flowering phase, is in the range up to 12.5%.
Stability assessment of maize hybrids by different methods in relation to their zoning
Authors:   Maize Research Institute, Kneja, 5835, Vulchinkov Stefan , Reseleshka L. ,   Maize Research Institute, Kneja, 5835, Vulchinkova Penka ,   Maize Research Institute, Kneja, 5835, Ilchovska Mima ,   Maize Research Institute, Kneja, 5835, Petrovska Natalya ,   Maize Research Institute, Kneja, 5835, Valkova Valentina ,   Maize Research Institute, Kneja, 5835
Published: June 2021

A many-sided evaluation of grain yield stability of 22 maize hybrids from the early group (FAO 300-400), tested in 4 locations was done. Different methods and models were applied: variation and regression analysis; AMMI and cluster analysis as well. A modified method for grouping of hybrids by mean yield and mean values of the regression coefficient bi was proposed. A good accordance between that method and AMMI-1 analysis was observed. The cluster analysis also confirms this consent. Calculated theoretical yields by locations create conditions for more precise zoning of hybrids according to environments.