bluuebunny/crossref_metadata_2025 huggingface dataset:
Manejo conservador da espondilodiscite após colpopexia sacral laparoscópica: relato de caso e revisão da literatura
Authors: Souza Stephany Paola , Guedes Fernanda Arbex , Wagner Nicole de Franco , Pedretti Beatriz , Paz Larissa Neves da
Published: August 2024

A colpopexia sacral é um procedimento cirúrgico realizado para tratar o prolapso uterino e outras condições relacionadas. Durante esse procedimento, o útero ou a cúpula vaginal é fixado ao ligamento sacral promontório. A técnica laparoscópica é frequentemente preferida por ser menos invasiva e oferecer uma recuperação mais rápida em comparação com técnicas cirúrgicas tradicionais. Durante a intervenção cirúrgica (convencional ou laparoscópica), a disseminação de bactérias para os tecidos da coluna vertebral é possível, assim como lesões teciduais que facilitam a entrada de agentes infecciosos. Além disso, a imunossupressão pós-cirúrgica e a implantação de dispositivos médicos podem aumentar o risco de infecção bacteriana. Nesse contexto, a cirurgia de colpopexia sacral pode resultar na inflamação ou infecção dos discos intervertebrais da coluna vertebral. Tal complicação é denominada espondilodiscite. O tratamento da espondilodiscite após colpopexia sacral pode ser desafiador, pois os pacientes já podem estar se recuperando de uma intervenção cirúrgica significativa. Nesse sentido, o manejo conservador é uma opção que envolve abordagens não cirúrgicas, como terapia antimicrobiana, uso de órteses, repouso, fisioterapia e acompanhamento médico regular. Em casos mais graves ou persistentes, pode ser necessária intervenção cirúrgica para drenagem de abscessos ou estabilização da coluna vertebral. Neste trabalho, será apresentado um relato de caso de espondilodiscite em uma paciente submetida a colpopexia sacral laparoscópica que foi tratada com sucesso através de uma abordagem conservadora. Destacamos os desafios diagnósticos e terapêuticos enfrentados durante o manejo dessa condição, além de revisar a literatura existente sobre o tema.
Fístula vesico-uterina (síndrome de youssef): descrição de caso e revisão da literatura
Authors: Araujo Cinara Silva , Fagundes Milena Klettenberg , Moitinho Beatriz Geraldo , Oliveira Lis Paulino de , Pinheiro Paula Castro
Published: August 2024

Introdução: As fístulas vesico-uterinas constituem as fístulas urogenitais menos frequentes, ocorrendo em 1 a 4% dos casos. A causa mais comum deste tipo de fístula é a cesárea, especialmente a de repetição. Youssef descreveu a doença em 1957, que posteriormente levou seu nome, sendo caracterizada pela tríade formada por hematúria clínica (menúria), continência urinária e amenorreia. O diagnóstico é feito por um ou mais métodos de imagem ou cistoscopia. O tratamento cirúrgico é o mais comum, entretanto, existem relatos de cura através do tratamento conservador. Materiais, sujeitos e métodos: Revisão realizada consultando-se as bases Medline/PubMed, SciELO e Revista Brasileira de Ginecologia e Obstetrícia, além das referências dos artigos consultados. Resultados e discussão: Evidências mostram forte correlação com parto cesáreo de repetição e fístula vesico-uterina devido ao aumento da proporção de cesáreas. Portanto, ao considerar o surgimento de fístulas vesico-uterinas, deve-se ter em mente este diagnóstico como uma possível complicação da cesárea.
Recomendações para a prática de exercício físico na gravidez: uma revisão crítica da literatura
Authors: Lima Thaís Gonçalves Camarço , Carvalho Geórgia Ribeiro , Neves Luiza Ferreira Rosa Costa , Costa Núbia Carolina Gondin Moraes da , Martins Nathália Quiel Barros
Published: August 2024

Introdução: Este artigo visa revisar criticamente a literatura sobre as recomendações para a prática de exercício físico durante a gravidez. A prática regular de exercícios físicos é geralmente encorajada para a população em geral devido aos seus inúmeros benefícios para a saúde. No entanto, a prática de exercícios durante a gestação requer considerações especiais devido às mudanças fisiológicas e anatômicas significativas que ocorrem durante este período. Esta revisão sistemática explora as diretrizes atuais, os benefícios, os riscos e as considerações específicas para a prática segura de exercícios físicos durante a gravidez. Foram revisados artigos brasileiros publicados entre 2010 e 2023. Os resultados mostram que, com orientação adequada, a prática de exercícios físicos é benéfica e segura para a maioria das gestantes. Conclui-se que há necessidade de mais estudos específicos e a conscientização entre profissionais de saúde sobre a importância da prática de exercícios físicos durante a gravidez.
Hiponatremia associada a antidepressivos: uma revisão
Authors: Castilho Érica Lopes , Zampiroli Izadora Zucolotto , Vieira Fernanda Henriques Miranda , Nava Jusciellyson da Silva
Published: August 2024

Introdução: A hiponatremia é um distúrbio metabólico caracterizado por reduzidos níveis séricos de sódio no organismo. Desidratação, doenças renais, hepáticas e uso de medicações, são algumas das causas para tal distúrbio. O presente estudo tem por objetivo avaliar através de uma revisão bibliográfica a relação entre a hiponatremia e o uso de antidepressivos. Materiais, sujeitos e métodos: Estudo de caráter observacional. Foram avaliados criticamente artigos encontrados nas plataformas PubMed, Scielo e Capes, utilizando as palavras chaves “hiponatremia” e “antidepressivo”. Resultados e discussão: Observa-se que o uso de antidepressivos possuem relação direta com o risco de hiponatremia. Os inibidores seletivos de serotonina são a classe que apresenta maior risco para esse, principalmente escitalopram e citalopram, uma vez que a serotonina age diretamente sob o hormônio anti-diurético (ADH), que quando secretado de forma inapropriada causa hiponatremia. Considerações finais:  Vários fatores têm que ser avaliados antes da prescrição de antidepressivos. Idade, sexo, medicações de uso contínuo, comorbidade, como também avaliar quais os efeitos colaterais que essas medicações podem gerar no organismo de cada um. Antes do início do tratamento, é importante a solicitação dos níveis sérios de sódio dos pacientes, mas também se faz necessário a dosagem desse durante o tratamento visto que a hiponatremia é um efeito-colateral comum em pacientes que utilizam antidepressivos e esse quando em níveis extremamente baixos podem levar a consequências sérias, como letargia, sonolência, crises convulsivas e estado comatoso.
Eficácia e segurança dos antipsicóticos atípicos nas demências: uma revisão sistemática
Authors: Sonda Marília , Chaer Beatriz Laboissiere , Souza Camila Twany Nunes de , Pereira Ingrid Vidal , Maciel Paula Geovana
Published: August 2024

Introdução: A expectativa de vida no Brasil tem aumentado nas últimas décadas, o que está associado ao aumento de doenças senis, como a demência. É comum a manifestação de sintomas psiquiátricos, como ansiedade, alterações de humor, agitação psicomotora e psicose em pacientes com demência, causando sofrimento tanto para os pacientes quanto para seus cuidadores. A identificação precoce desses sintomas pode proteger os pacientes de um declínio cognitivo acelerado e reduzir o estresse dos cuidadores. Objetivo: Revisar o uso de antipsicóticos atípicos em síndromes demenciais, analisando a segurança e eficácia desses medicamentos nessa população. Metodologia: Foi realizada uma revisão sistemática da literatura, utilizando estudos publicados nas plataformas SciELO, Google Acadêmico e PubMed nos últimos cinco anos, com os descritores: demência, antipsicóticos atípicos e manejo das síndromes demenciais. Resultados e Discussão: Os antipsicóticos atípicos demonstram efeitos positivos nas manifestações psicóticas em adultos e idosos, com menos efeitos colaterais que os antipsicóticos típicos, sendo a primeira escolha terapêutica para manifestações psiquiátricas em demências. Considerações Finais: Sintomas comportamentais são comuns em pacientes com demência. A análise criteriosa e o uso de medidas comportamentais devem preceder o tratamento medicamentoso, considerando os possíveis efeitos adversos graves dos antipsicóticos atípicos, como eventos cerebrovasculares e mortes.
Mulheres usuárias de crack: revisão sistemática da literatura brasileira
Authors: Pfeil Heitor Bortolucci , Menezes Isabella Alves de , Oliveira Paula Barros Borges de , Passos Arthur Mendes Porto
Published: August 2024

Introdução: A prevalência do uso de cocaína e derivados, como o crack, é alarmante nos tempos atuais devido ao seu grande potencial de dependência, com absorção na corrente sanguínea em cerca de quinze segundos a partir da via inalatória. Este artigo tem como objetivo traçar o perfil destes usuários, principalmente mulheres, visando viabilizar políticas públicas profiláticas e terapêuticas para essa dependência. Materiais, sujeitos e métodos: Para sua elaboração, foram consultados artigos científicos referenciados na Medline/PubMED, SciELO e Cochrane entre 2000 e 2024, bem como reportagens em jornais virtuais idôneos. Resultados e discussão: A pesquisa demonstrou predominância das seguintes características de usuárias de crack no Brasil: solteiras, mães (de filhos vivos ou não), desempregadas, com ensino fundamental incompleto. Além disso, as mulheres têm mais predisposição ao suicídio (50%) em relação aos homens (34%). O uso abusivo de crack também é mais intenso (em quantidade da substância) em mulheres do que em homens, assim como o risco de infecções sexualmente transmissíveis. Considerações finais: A pesquisa evidencia diferenças significativas que fazem da população feminina usuária de crack um grupo merecedor de intervenções públicas que vão além do âmbito de saúde, incluindo também aspectos sociais, previdenciários e educacionais.
Mortalidade em pacientes psiquiátricos: revisão bibliográfica
Authors: Soares Camila Pavei , Hoffer Jamille , Nogueira Isabela Cristina Ruzza , Vilanova Mariana Lorena Silva
Published: August 2024

Este artigo revisa as altas taxas de mortalidade entre pacientes psiquiátricos, comparando dados de estudos internacionais e nacionais. A pesquisa avaliou a sobremortalidade em pacientes de hospitais psiquiátricos no Rio de Janeiro (1995-2000), revelando um risco relativo de 3,58 vezes maior em comparação à população geral. Fatores como doenças cardiovasculares, diabetes e síndrome metabólica contribuem significativamente para a alta mortalidade por causas naturais. Além disso, o suicídio emerge como a principal causa de morte não natural, sendo 12 vezes mais comum entre esquizofrênicos. Dados de Sorocaba (2004-2011) mostraram mortalidade 118% maior nos manicômios locais, indicando negligência e a necessidade de reforçar a reforma psiquiátrica. A revisão integrativa da literatura (2015-2020) destacou a depressão e o uso de drogas como fatores críticos para o comportamento suicida. Os resultados sublinham a urgência de políticas de saúde mais integradas e preventivas, focando na redução da mortalidade evitável e na melhoria do atendimento psiquiátrico.
Colecistite enfisematosa aguda. Relatório de um caso e revisão da literatura
Authors: Araujo Luana Villete de , Flores Larissa Martins , Vieira Ana Laura Soares , Borges Carine Vilela Ferreira
Published: August 2024

A colecistite enfisematosa aguda é uma forma rara e grave de inflamação da vesícula biliar, caracterizada pela presença de gás na parede da vesícula ou no sistema biliar. Este artigo apresenta o relato de um caso clínico de colecistite enfisematosa aguda em um paciente de 65 anos, revisando a literatura atual sobre a patologia. Discutimos a epidemiologia, etiologia, apresentação clínica, métodos diagnósticos, tratamento e prognóstico desta condição. Através deste estudo, objetivamos fornecer uma compreensão abrangente da colecistite enfisematosa aguda, destacando a importância de um diagnóstico precoce e tratamento adequado para melhorar os desfechos clínicos.
Doença do refluxo gastroesofágico: uma revisão da literatura
Authors: Rodrigues Emilly Bruna Soares , Coquemala Júnior Carlos Nei , Pissolato Maria Luisa Ribeiro , Flizikowski Rayanne Timóteo de Sousa
Published: August 2024

A Doença do Refluxo Gastroesofágico (DRGE) é uma condição crônica que afeta uma parcela significativa da população mundial. Caracteriza-se pelo retorno do conteúdo gástrico para o esôfago, resultando em sintomas como azia e regurgitação. Esta revisão sistemática da literatura tem como objetivo avaliar os avanços recentes no diagnóstico, tratamento e manejo da DRGE. A metodologia incluiu a busca de artigos em bases de dados científicas, seguindo critérios específicos de inclusão e exclusão. Os resultados indicam que, apesar dos avanços no entendimento da fisiopatologia da DRGE, ainda há desafios significativos na sua gestão, particularmente em pacientes refratários ao tratamento convencional. Concluímos que há necessidade de mais estudos que abordem abordagens terapêuticas inovadoras e personalizadas.
Neoplasia avançada de esôfago: uma revisão da literatura
Authors: Costa Ana Carolina Carvas , Abbes Marcela Marques , Oliveira Maria Clara Moreira de , Amaral Maria Luiza Megale Brandão Gurgel do , Morais Renato Augusto Fonseca
Published: August 2024

A neoplasia avançada de esôfago representa um desafio significativo no campo da oncologia devido à sua alta mortalidade e complexidade de tratamento. Esta revisão sistemática da literatura visa sintetizar os avanços mais recentes no diagnóstico, tratamento e prognóstico dessa condição. Foram incluídos estudos publicados entre 2010 e 2023, buscando fornecer uma visão abrangente das abordagens terapêuticas, resultados clínicos e perspectivas futuras. A análise indica que, embora tenham ocorrido avanços significativos em terapias multimodais, a sobrevida a longo prazo ainda é limitada. A compreensão aprimorada dos mecanismos moleculares e a inovação tecnológica são essenciais para melhorar o manejo e os resultados dos pacientes.
Biomarcadores no líquido amniótico e prognóstico fetal: uma revisão de literatura
Authors: Cadore Fernanda Gabrielle , Carvalho Maria Isabel Cardoso dos Passos , Fagundes Beatriz Vilela , Fernandes Gabriela Cavalcante
Published: August 2024

Introdução: Biomarcadores são ferramentas essenciais no diagnóstico e prognóstico de enfermidades fetais. A detecção clínica precoce é fundamental para a abordagem materna e redução de complicações fetais. O líquido amniótico reflete a condição fisiológica do feto. Este artigo revisa a literatura sobre a importância dos biomarcadores no líquido amniótico para o prognóstico fetal. Material, sujeitos e métodos: Foi realizado um levantamento bibliográfico na base de dados MEDLINE-Pubmed entre 2019 e 2024. Utilizaram-se artigos em inglês com os filtros “clinical trial” e “review”, e os descritores “amniotic fluid” e “biomarker”. Resultados e discussões: Todos os artigos selecionados demonstraram que os biomarcadores no líquido amniótico são ferramentas valiosas para o diagnóstico de doenças e mutações genéticas, oferecendo um bom prognóstico fetal. Considerações finais: O líquido amniótico contém informações valiosas sobre o desenvolvimento e metabolismo fetal. O uso de biomarcadores permite o diagnóstico precoce de complicações maternas e fetais, destacando seu papel crucial na triagem de gestantes de risco.
Fotografía de portada_Vol 12(1)
Authors: Alduncin Juan
Published: August 2024

Se desea mostrar el hornero en primera plana, cercano y en interacción con actividades antrópicas que sucedían en el lugar.
An Analysis of the Role of Work Motivation and Work Discipline in Improving Employee Performance: Job Satisfaction as a Mediating Factor (Case study on PT Prima Sejati Sejahtera I)
Authors:   Management Study Program, Atma Bhakti College of Economics, Surakarta, Kristiyanto Bayu , Handayani Rini ,   Management Study Program, Atma Bhakti College of Economics, Surakarta
Published: August 2024

This study analyzes how worker motivation and discipline affect performance through job satisfaction. Using primary data, this study is quantitative. This study took a sample of all workers totaling 48 people because the population was below 100. Path analysis and multiple linear regression are used. The hypothesis of this study produces the following conclusions: work motivation, discipline, and job satisfaction improve employee performance at PT Prima Sejati Sejahtera I. Work motivation and discipline increase job satisfaction in employees. PT Prima Sejati Sejahtera I workers will be more productive when job satisfaction is high, because they can moderate the relationship between work motivation and work discipline.
Evaluation of the Financial Reporting System of LKM Gapoktan Tani Manunggal Temanggung using Black Box Testing
Authors:   Politeknik Negeri Semarang, Jl. Prof. Sudarto, Tembalang, Kec. Tembalang, Kota Semarang, Jawa Tengah 50275 Indonesia, Mansur Ahmad Wafa , Mardinawati Mardinawati ,   Politeknik Negeri Semarang, Jl. Prof. Sudarto, Tembalang, Kec. Tembalang, Kota Semarang, Jawa Tengah 50275 Indonesia, Hidayati Ulfah ,   Politeknik Negeri Semarang, Jl. Prof. Sudarto, Tembalang, Kec. Tembalang, Kota Semarang, Jawa Tengah 50275 Indonesia, Supaya Sandi ,   Politeknik Negeri Semarang, Jl. Prof. Sudarto, Tembalang, Kec. Tembalang, Kota Semarang, Jawa Tengah 50275 Indonesia
Published: August 2024

This study employs Boundary Value Analysis (BVA), a kind of Black-Box Testing, to assess the financial information system of LKM Gapoktan Tani Manunggal Temanggung. Through testing the system's performance in a variety of edge situations pertaining to user registration, login, financial data entry, balance calculation, report creation, data storage, backup, alerts, and system accessibility, the research seeks to evaluate the functionality of the system. The outcomes demonstrate how well the system manages boundary circumstances, producing precise outputs and guaranteeing dependability across various functionality and devices. The study emphasizes the system's resilience and points out areas that may benefit more development, such as enhanced security, better user experience, integration testing, and sophisticated testing methods.
Validity and reliability of motor competence assessment as an instrument measuring fundamental motor skills for 12-year-olds in Indonesia
Authors: Putro Baskoro Nugroho , Kristiyanto Agus , Hidayatullah Mohammad Furqon , Handayani I Gusti Ayu Ketut Rachmi
Published: August 2024

The research aims to assess the validity and reliability of the Motor Competence Assessment (MCA) instrument for 12-year-olds. The validity and reliability test provides a comprehensive framework for objectively measuring motor competence and identifying areas for intervention to enhance motor skill development. The study included 321 participants (156 male and 165 fe-male) from diverse Indonesian elementary school backgrounds. Motor competence assessment involved six test components, each conducted with two trials. Validity was assessed through exploratory factor analysis (EFA), and reliability was assessed via Cronbach's alpha, with raw data converted to a scale for EFA. The Kaiser-Meyer-Olkin (KMO) & Bartlett Test results and the Sampling Ade-quacy (MSA) measure are suitable for running EFA because they show more than 0.50. The standards for each item were met in the Communalities test by showing an extraction of >0.50 for each item. The MCA instrument proved valid because each test item (variable) firmly attaches to one instrument. Reliability tests, using Cronbach's Alpha, show that MCA instruments are reliable and usable. The Motor Competence Assessment (MCA) instrument demonstrates validity and reliability in measuring motor skills. Ex-ploratory factor analysis (EFA) identifies two main components: locomotor skills and stability and manipulative motor skills. Cronbach's alpha further confirms MCA's reliability. Its effectiveness in various contexts, including physical education and rehabilitation, supports targeted interventions. Understanding motor skill development with MCA enhances tailored approaches for individu-als, promoting physical well-being and performance.
Keywords: physical education, motor skill, elementary school, assessment.
Article RETRACTED: include references that are unrelated to the subject of the article and/or the context in which they are cited The effects of circuit training versus high-intensity interval training on the endurance of volleyball athletes: a randomized controlled trial
Authors: Latino Francesca , Susanto Nugroho , Anam Khoiril , Setyawan Hendra , Saraiello Emma , Tafuri Francesco
Published: August 2024

Despite its intermittent nature, volleyball places significance on a high aerobic capacity, particularly evident in multiset games that demand sustained high-performance levels. Various training approaches exist to enhance the endurance of volleyball athletes. Thus, the fundamental aim of this research is to examine the contrasting effects of utilizing high-intensity interval training (HIIT) and circuit training methods to enhance volleyball athletes' endurance. The study used an Experimental group that partook in a HIIT training regime, and a Contrast group that undertook a Circuit training program. Thirty male volleyball players aged between 17 and 22 years (M=19.14; SD±1.61) were purposefully selected for the study and split into Contrast and Experimental groups of 15 each. At the beginning and end of the intervention programs both groups underwent physiological assessments for Maximum Oxygen Consumption (VO2max), Heart Rate Recovery (HRR), Peak Inspiratory Flow (PIF), Peak Expiratory Flow (PEF), and Force Vital Capacity (FVC). As result a meaningful Time x Group interaction for the VO2max, HRR, PIF, PEF and FVC was observed. This represents a significant improvement in the treatment group (p < 0.001). No material change was observed in the comparison group. Findings revealed that the HIIT training approach outperformed the circuit training method in enhancing volleyball athletes' endurance. Consequently, it is should be beneficial for volleyball players to incorporate HIIT into their standard training regimens.
Keywords: VO2max; physiology; sport; exercise; aerobic capacity.
Characteristics of injury to weightlifting athletes in Indonesia
Authors: Solikah Nur Luthfiatus , Apriantono Tommy , Hasan Muhamad Fahmi , Fathannisa Tuliss Bial , Ramania Nia Sri , Pambudi Yudhi Teguh , Firmansyah Awang
Published: August 2024

Weightlifting is requires maximum strength, speed, and explosive power in order to lift maximum weight. Weightlifting carries a risk of injury which can result in pain, damage and limitation of bodily functions. The aim of this study is to describe and characterize of injuries that occur in weightlifting sports. This retrospective cohort study using a questionnaire that valuated 111 male lifters who were currently had experienced injuries. The result that, characteristics of athletes are an average age of 16.4 ± 3.7, height 161.2 ± 8.9, body weight 60.7 ± 14.9, body mass index 23.2 ± 4.7, arm length 67.9 ± 8.8, and leg length 90.4 ± 8.8 who have chronic injuries (67%) occurred during exercise (87%) and most injuries occurred in the upper limb (62%). Locations of injuries are shoulders (57%), wrists (10%), back (33%), hip/groin (10%), hamstring (16%), and knees (35%) with the types of injury experienced athletes are muscle strains (33%), ligament sprains (32%), and impingement (35%). 87% of athletes are injured during practice while 13% are injured during competition. To sum up, this study shows that the characteristics of major injuries occur in the upper extremities, namely the shoulder and the incident injuries occur during exercise.
Keywords: Weightlifter, Performance, Injury, Training Programs
What is the best predictor of body fat percentage for older brazilian women?
Authors: De Oliveira Damasceno Vinícus , Macedo Vianna Jeferson , Barreiros Cardoso Bomfim Alexander , EDSON DE SOUZA DANILO , Felix da Silva Jakson , Vinícius Letieri Rubens , Dos Santos Costa André , Perrout de Lima Jorge
Published: August 2024

This study aimed to investigate the validity of several equations and predictive indices for estimating body fat percentage (%BF) in 152 older women, with an average age of 67.4 years and an average body mass index (BMI) of 28.65 kg/m². To this end, anthropometric measurements including height, body weight, circumferences (waist and hip), and a dual energy X-ray absorptiometry (DXA) scan were performed. All measurements were performed by trained researchers following specific protocols. The results were compared to the dual energy X-ray absorptiometry (DXA) technique, which is considered the reference method. The analyzed equations showed moderate to good correlation coefficients with DXA, with particular emphasis on Visser’s equation 6, which showed the best correlation (r = 0.752, p < 0.001). However, the agreement between the equations and DXA, as assessed by the Lin concordance coefficient, was classified as poor (ρc < 0.90). This indicates that although the equations have a positive correlation with body composition, they tend to deviate from the identity line when compared to the reference method. Additionally, the equations showed high sensitivity for detecting obesity when the cut-off point of 30% body fat was adopted, indicating a good ability to identify the presence of the condition. However, the equations, with the exception of equation 4, showed low specificity, meaning they had limited ability to detect normal individuals, resulting in a low negative predictive value. The results suggest that BF% equations and indices are dependent on the populations in which they were developed. The specificity and sensitivity of these equations may vary, and it is important to carefully select the most appropriate equation for estimating BF% in older Brazilian women.
Keywords: Anthropometry; body composition; older adults.
Research trends in manual therapy: a bibliometric review of the last 10 years
Authors: Bartik Peter , Ahmad Shakil , Adil Hafiz Muhammad , Šagát Peter , Sekáč Jaroslav
Published: August 2024

Manual therapy (MT) is a dynamic entity progressing rapidly. The current trend stimulates a direction toward higher specificity in the research. This is the first bibliometric review to identify the trends in MT in the last ten years (till 2023). The Scopus database was selected to retrieve the bibliographic records. Biblioshiny (Bibliometrix), PowerBI, MS Excel, and MS Access were used to visualize and analyze the results. 1208 relevant studies were included in the analysis. Publishing has a rising character. The four-author articles are the most common, while only 68 are single-author studies. In 2021, the highest number of publications (n=178) was published. The Journal of Bodywork and Movement Therapies has published the highest number of publications (75). The USA is the most prolific country in publishing (361 studies) and total citations (4869). Universidad Rey Juan Carlos (Spain) is the most productive and cited institution. Fernández-De-Las-Peñas C. is the most productive, and Mark D. Bishop is the most cited author. The USA, Australia, Canada, and European countries have the most frequent collaborations. MT was the most common research focus from 2017 to 2019. The topics of exercise therapy, musculoskeletal therapy, physical therapy, and physiotherapy have been the focus of research in the context of MT lately. The present study reported the research-related trends in MT applying bibliometric methods and identified the most productive countries, institutions, and researchers over the past decade. These findings are intended to assist the researchers in better orientation in the research field and to specify the trends for future research studies.
Keywords: Manual therapy; physiotherapy; research trends; bibliometrics; thematic evolution; research collaboration
Pérdida de rendimiento en sprints resistidos asociado a la madurez en jóvenes futbolistas (Performance loss in resisted sprints associated with maturity in young soccer players)
Authors: Fernández Galván Luis Miguel , Castaño-Zambudio Adrián , Gil-Arias Alexander , Casado Arturo
Published: August 2024

El objetivo fue determinar la influencia del estado madurativo en la pérdida de rendimiento del sprint y del sprint resistido en jóvenes futbolistas. Se evaluó la madurez biológica en 56 participantes y se agruparon según los años predichos a partir de la pico de velocidad de crecimiento (PHV) (pre-, mid- y post-PHV). Las diferencias entre grupos se determinaron a través de análisis de covarianzas. El tiempo del sprint de 30 m se midió mediante la aplicación MySprint. En el sprint de 5 m se observó una mayor pérdida de rendimiento entre mid- y pre-PHV que entre post- y mid-PHV (ES = -0.90 a -0.57 vs -0.52 a -0.34). En 30 m se mostró una mayor pérdida entre post- y mid-PHV que entre mid- y pre-PHV (ES = -1.04 a -0.69 vs -0.81 a -0.56). Es importante considerar el desfase madurativo en la optimización del sprint a largo plazo en jóvenes deportistas.
Palabras clave: Maduración biológica, fútbol, entrenamiento de sprint resistido, adolescente.
Abstract. The objective was to determine the influence of maturational status on the loss of sprint performance and resisted sprint performance in young soccer players. Biological maturity was assessed in 56 participants, who were grouped according to predicted years from peak height velocity (PHV) (pre-, mid-, and post-PHV). Differences between groups were determined through covariance analysis. The 30 m sprint time was measured using the MySprint application. For the 5 m sprint, a greater performance loss was observed between mid- and pre-PHV compared to post- and mid-PHV (ES = -0.90 to -0.57 vs. -0.52 to -0.34). Over 30 m, a greater loss was observed between post- and mid-PHV compared to mid- and pre-PHV (ES = -1.04 to -0.69 vs. -0.81 to -0.56). It is important to consider maturational timing in the long-term optimization of sprint performance in young athletes.
Keywords: Biological maturation, football, resisted sprint training, adolescents.
Desarrollo de un aplicativo móvil con Node.js para la venta de productos agrícolas en MiPymes
Authors: Palmera Quintero Luis Manuel , Ríos Barona Danny Jhoan , León Karen , Chinchilla Torres Francisco
Published: August 2024

En el desarrollo de aplicaciones móviles, el diseño se convierte en un elemento central después de tener una visión clara de cómo sería la aplicación. La estructura de las aplicaciones móviles implica algo más que estética, sino también arquitectura de la información, usabilidad y experiencia de usuario (UX). En este sentido, se toma como un estudio de investigación aplicada en particular para contribuir a promover las capacidades de comercialización en las Micro, Pequeñas y Medianas Empresas (MIPYMES) en relación con su sector. La iniciativa se inspiró en una metodología de desarrollo ágil denominada Programación Extrema (XP), reconocida por su orientación cooperativa y rápida entrega de software funcional. Para la investigación la población objetivo fueron las Pymes agrícolas, las cuales constituyen un aspecto significativo de la economía y sostenibilidad de varias comunidades. El estudio tuvo como objetivo crear una infraestructura tecnológica sólida y eficiente que respalde de manera integral las operaciones de un aplicativo móvil destinado a la comercialización de productos agrícolas en pequeñas y medianas empresas (MiPymes). Se empleó Node.js como tecnología fundamental para la creación del Backend en virtud de su eficacia en el desarrollo de aplicaciones móviles a gran escala y de alto rendimiento. Esta elección tecnológica permitió al equipo de desarrollo diseñar una plataforma móvil confiable y fácil de usar que respondiera a necesidades agrícolas particulares. Los resultados mostraron que el Backend desarrollado con Node.js integrará API RESTful que facilitarán la conexión y el intercambio de información entre los productores agrícolas y los compradores. Esta integración permitirá una comunicación fluida y en tiempo real, mejorando la experiencia del usuario y fomentando relaciones comerciales más eficientes y efectivas.
Penerapan Algoritma Huffman Coding Dalam Menghemat Ruang Penyimpanan Data Multimedia File (Teks dan Gambar) Berbasis Python
Authors: Hasan Syahril , Abdullah Saiful Do , Ambarita Arisandy
Published: August 2024

Abstrak: Kompresi adalah teknik yang digunakan untuk mengompres data agar sesuai dengan ukuran pada media yang digunakan. seperti backup data, transmisi data, dan keamanan data. Algoritma Huffman dalam kompresi teks dapat menghasilkan pengurangan ukuran file yang signifikan tanpa kehilangan informasi, struktur pohon Huffman dan pengkodean karakter memberikan wawasan yang mendalam tentang cara algoritma bekerja. Metode Pengembangan yang gunakan adalah Algoritma Huffman yang di mulai dengan Pengumpulan Frekuensi, Pembuatan Tree Huffman, Pembuatan Kode Huffman, Pembuatan Tabel Kompresi, dan Kompresi Data. System ini dibangun dengan menggunakan bahasa pemrogram Phyton yang di terjemahkan pada Visual Studio Code yang mempermudah dalam menganalisa logika perhitungannya sehingga menghasilkan sistem kompresi data file teks dan gambar yang dapat menghemat ruang data multimedia file teks dan gambarKata kunci: Data kompres teks dan gambar; Huffman coding; Aplikasi pythonAbstract: Compression is a technique used to compress data to match the media size, such as backup Compression is a technique used to compress data to match the size of the media used, such as data backup, data transmission, and data security. Huffman's algorithms in text compression can result in significant file size reductions without losing information, Huffmann's tree structure and character encoding provide in-depth insight into how the algorithm works. The developmental methods used are the Huffman algorithm, which starts with Frequency Collections, Huffman Tree Compression, Huftman Code Composition, Compression Tables, and Data Compression. The system is built using the Phyton programming language translated into Visual Studio Code which makes it easy to analyze the logic of the calculation, resulting in a data compression system of text and image files that can save multimedia data space for text and picture files.Keywords: Text and image data compression; Huffman coding; Python Applications
The Role of Virtual Reality in Patient Education: Exploring how Virtual Reality Technology can be used to Educate Patients about Complex Medical Procedures or Health Conditions
Authors:   USA, Yadav Vivek
Published: August 2024

The purpose of this study is to see the extent of VR technology use in patients’ education concerning modern medical procedures and their conditions.
“XITOY-O‘ZBEKISTON-QIRG‘IZISTON” TRANSPORT YO‘LAGI TASHKIL ETILISHIDA O‘ZBEKISTON ISHTIROKINING TARIXIY AHAMIYATI
Authors: Gulmatov Umarali
Published: August 2024

Mazkur maqolada muhim transport loyihalaridan biri bo‘lgan “Xitoy-Qirg‘iziston-O‘zbekiston” multimodal yo‘lining barpo etilishida O‘zbekistonning o‘rni va ahamiyatini turli tahlillar asosida ochib berilgan. Ushbu yo‘l “Bir makon, bir yo‘l” loyihasi asosida olib borilishi va unda Respublikaning faol ishtiroki muhim ahamiyatga ega. Negaki, mazkur transport yo‘lagi qadimgi Buyuk ipak yo‘lining zamonaviy shakli hisoblanib, Osiyo hamda Yevropa davlatlari o‘rtasida mustaham iqtisodiy-ijtimoiy ko‘prik vazifasini bajaradi. Bundan tashqari, mazkur loyihani tashkil etishdagi ijobiy va salbiy holatlar, muammolar va yechimlar to‘g‘risida ham fikrlar bayon etilgan.
Peningkatan Ranah Kognitif Melalui Metode Schaffolding Pada Pembelajaran Pendidikan Agama Islam
Authors: Mira Mira , Takdir Takdir , Fitriani Fitriani , P Sudirman
Published: August 2024

This study aims to determine the increase in the cognitive domain of students through the scaffolding method in PAI learning in Class XI OTP 4 at SMKN 1 Sinjai. This study used the type of PTK research, the subjects in this study were 25 students in class XI OTP 4 and the researcher as the executor of the applied method and the teacher as the observer. The type of action applied is that there are two cycles, where each cycle consists of 4 stages, namely planning, action, observation, and reflection. Used were observation, tests, and documentation. Analysis technique is using validity test, reliability test, descriptive statistical observation, and N-Gain analysis. The results showed that in the first cycle of action, the average score of students was 0.4304 in the low category. While in the action cycle 2 obtained as much as 0.7443 with the high category. Therefore, it can be concluded that the application of the scaffolding method can improve the cognitive domain of students in PAI learning in Class XI OTP at SMKN 1 Sinjai.
Evaluation of virulence factors in Stenotrophomonas maltophilia: a systematic review
Authors: Jassim Lamiaa Mohammed , Abbass Sura Mouaid , zeadan Ayat majeed , Selman Rawaa Saadi
Published: August 2024

Stenotrophomonas maltophilia is a common microorganism that is linked to opportunistic illnesses. Growing prevalence and severity of sickness were seen in immunocompromised hosts, especially opportunistic bloodstream infections and pneumonia syndromes. The present research involved studies published from PubMed and Google Scholar databases resulting in 100 open-access articles. A systematic review and meta-analysis were performed to study virulence factors of S. maltophilia as well as genes that play a role in bacteria’s resistance to antibiotics that contribute to increased bacterial pathogenicity. The result showed virulence factors of S. maltophilia include (fimbrial operon , extracellular enzymes), biofilm production, antibiotic-resistant gene having the main roles in bacteria pathogenicity. In conclusion: S. maltophilia have a significant death rate, and the risk factors for mortality depend on the early diagnostic state and patient population. Additionally, to reduce bacteria’s resistance to antibiotics, appropriate treatments must be used to treat and control infection.
Influence of Leaders Risk Taking and the Sustainability of Savings and Credit Co-Operatives in Kenya
Authors: Warwathe David
Published: August 2024

Purpose: The purpose of the study was to explore the influence of risk taking by leaders on the sustainability of SACCOs in Kenya. The study sought to provide insights on the key focus areas, which contribute towards the sustainability of SACCOs in Kenya. The study was confined to SACCOs within 5 Counties of Nairobi, Kiambu, Machakos, Muranga and Kajiado A sample size of 174 SACCOs was taken.
Methodology: Descriptive research design was adopted for this study. The use of objective and quantifiable data enabled the researcher to generalize the results of the study to the entire population. The correlation coefficient between SACCO sustainability and risk taking is 0.488 with a p-value of 0.000 for a 5% 2-tail test.
Findings: The study concludes that leaders risk taking positively influence sustainability of SACCOs in Kenya.The results of the study also imply that if the SACCOs leaders take risk and venture into unexploited area, they are swift to abandon unprofitable products and also are experienced in risk management; they will be able to guarantee sustainability of their SACCOs.
Unique Contribution to Theory, Practice and Policy: From the findings of the study, it can be noted that government regulations moderates the variable resulting to possibility of the sustainability of such SACCO. The study has important implications on the appropriate conceptualization of sustainable business models in the context of SACCOs. This study encourages management committees, to take risk by venturing into new areas, take credit to introduce new products and abandon those products that are unprofitable for their SACCO sustainability.
The Impact of Musical Training on Linguistic Skills in Children: A Review
Authors: Hong Andrew
Published: August 2024

This paper evaluates the idea of musical education and its benefits on children at the elementary school age.  Music has been and will continue to be a part of people's lives, so it is important to investigate bringing it to the field of education.  This article discusses the effects of musical education on children’s linguistic skills.  It also, if applicable, seeks to find throughlines and common threads between curricula that achieve successful results with children to isolate the important factors that make music more beneficial.  Musical education was found to improve phonological awareness abilities in children, most commonly 4-6 years old, and a wide variety of musical curriculums were further found to have a positive impact on children’s linguistic skills.
Novel Immunotherapies for the treatment of Acute Lymphoblastic Leukemia
Authors: Barros Isabella , Dame Haley
Published: August 2024

CAR T-cell therapy and immune checkpoint inhibitors are groundbreaking immunotherapies with great promise for cancer treatment. CAR T-cell therapy uses engineered T-cells from the patient to help the immune system better identify and eliminate cancer cells. Immune checkpoint inhibitors for PD-1 and PD-L1 use monoclonal antibodies to block the PD-1/PD-L1 interaction that would otherwise allow cancer cells to go unnoticed by the immune system, continuing the growth of the cancer. For acute lymphoblastic leukemia (ALL), CAR T-cell therapy has led to favorable responses, with the potential to induce complete remission. Conversely, the PD-1 and PD-L1 immune checkpoint inhibitors have not shown a significant effect on the disease. Though CAR T-cell therapy is an effective treatment for ALL, its accessibility is impacted by cost and lack of availability. With the initiation of further clinical trials, commercialized CAR T-cell therapy could become more widely available, thus lowering the cost of treatment, and increasing accessibility.
Microbial Engineering for PHB Production and E-Waste Biomining: A Sustainable Approach
Authors: Nagrani Kush , Zytnick Alexa
Published: August 2024

This review delves into the potential of microbial biotechnologies in tackling two major environmental issues that face modern society: the manufacturing of petroleum-based plastics and the management of electronic waste (E-waste). E-waste contains valuable and critical metals that are conventionally extracted using methods that pose a threat to the environment (Gopikrishnan et al., 2020). Through the novel process of biomining, microorganisms have been found to offer a more sustainable way of extracting these metals. Similarly, the production of ecologically-damaging petroleum-based plastics can be mitigated by biologically modifying microorganisms that are naturally capable of producing bioplastics, like polyhydroxybutyrate (PHB), intracellularly (Tsang et al., 2019). This study addresses the current state of these microbial technologies as well as their drawbacks, ultimately culminating in a set of solutions that provide ways for these processes to be scaled up to an industrial level.
The Effect of Antioxidants on Olfactory Dysfunction in Parkinson's Disease
Authors: Pandey Neelesh , Schmidt Tiffany
Published: August 2024

Parkinson’s disease is one of the most prevalent diseases worldwide, with approximately 10 million people worldwide being affected in 2016. Olfactory dysfunction is a common hallmark of early Parkinson’s disease, and research indicates that antioxidants work against reactive oxygen species(ROS) in Parkinson’s disease. Lewy bodies,  alpha-synuclein protein aggregates, are the cause of the death of dopaminergic neurons in Parkinson’s disease. Given olfactory dysfunction is one of the first symptoms of Parkinson’s disease, it has intrigued many to discover its underlying importance. When Lewy bodies are found in the olfactory bulb, there was a greater than 90% correlation with the presence of Parkinson’s disease. It has been observed that alpha-synuclein aggregation may begin in the olfactory bulb before moving to other parts of the brain. Free radicals, such as ROS, are related to dopamine such as oxidized dopamine, and can help sustain alpha-synuclein toxic forms, leading to aggregation. Therefore, antioxidants could play a substantial role in mediating the effects of ROS. This paper will review our current understanding of the usage of antioxidants in alleviating the symptoms posed by oxidative stress and what that could mean for Parkinson’s disease models by providing a critique of 4 papers. Each paper will discuss the usage of treatment for olfactory dysfunction and the potential implications that follow the results. After, the paper will propose new studies to determine whether antioxidants are effective in diminishing the extent of olfactory dysfunction in patients with Parkinson’s disease.
Adaptive Therapy: Using Evolutionary Game Theory to Combat Cancer Treatment Resistance
Authors: Iyer Leela , Brooks Becca
Published: August 2024

Adaptive therapy is a cancer treatment based upon the principles of evolutionary game theory (EGT) utilized to minimize treatment resistance as a cause of tumor evolution. This treatment strategy incorporates a foundation of Darwinian evolutionary principles with mathematical modeling and clinical data.  As a result, adaptive therapy ameliorates the negative effects of traditional cancer treatments such as therapy resistance and a debilitated quality of life. By eliminating the use of maximum tolerated dose (MTD), the hallmark of traditional therapies, the evolutionary properties of tumors to develop drug resistance are circumvented and the probability of a prolonged life for patients is significantly increased. This paper explores the effectiveness of an expanded usage of adaptive therapy through an evaluation of current oncological research.
Statistical analysis of methylation reveals epigenetic biomarkers for high- functioning autism spectrum disorder
Authors: Sharma Aarav , Lee Hayan
Published: August 2024

Autism spectrum disorder (ASD) is a neurological disorder that affects social behavior and learning ability. Although studies have identified certain regions of the genome (22q13.33) linked to the increased risk of ASD, there is no clear etiology, which is why psychologists theorize that ASD is a complex interaction between genetic and environmental factors. The current study was designed to identify genes with a positive correlation toward the diagnosis of high-function autism spectrum disorder (HF-ASD). Samples were obtained from National Center for Biotechnology Information (NCBI) containing 450K CpG methylation from 69 subjects diagnosed as HF-ASD or typically developing (TD). We applied Principal Component Analysis (PCA) and further utilized two sample Kolmogorov-Smirnov test (KS-test) to obtain the p-values for each patient. False Discovery Rate (FDR Correction) is computed by Benjamini-Hochberg Procedure. Based on the output of the FDR method, we identified the top ten genes that have CpGs with statistically differentially methylated. Such potential epigenetic biomarker includes WBP11, LDHB, DHX29, NUB1, C2orf67, SNAI2, MTOR, CLCN3, SYNJ2BP, and TTK. Two sample KS test and FDR Correction code is available at: https://www.kaggle.com/code/aaravsharma123/gse109905-fdr-pvalues/notebook.