bluuebunny/crossref_metadata_2025 huggingface dataset:
Determination of Modes in the Ice–Water Bi-layer Waveguide
Authors: Tang Shengyu , Zhu Guangping , Wang Xiaoyu , Yin Jingwei
Published: December 2021

The seismic method on ice provides rich information and a feasible technical way for acoustic study in ice-covered water. This paper presents a method to determine the modes in ice–water bi-layer waveguides. We achieve the purpose by deducing the scaled boundary formulation for solid and fluid layers then coupling them with the coupling matrix. The wave numbers and mode shapes are compared with the results of the finite element method. It shows that the configuration for ice–water bi-layer waveguide is of high precision. In underwater acoustic applications, the depth of water is comparatively large relative to ice thickness, which addresses the additional difficulty of accuracy in high frequency. The study on convergence is carried out, and approximate formulas are addressed based on the calculated results, giving a quick insight into piratical application.
Resolution and Quality Issues in 3D Analysis of Inscribed Signs: An Example from Cypro-Minoan Inscriptions
Authors: Polig Martina , Hermon Sorin , Bretschneider Joachim
Published: December 2021

A recurrent demand in many archaeological digital documentation systems is the need for an accurate as possible registration of data. Somehow, contrary to this request, are efforts led by various computer science groups dealing with 3D documentation and focusing on developing fast and cheap solutions to record 3D models of archaeological assets. The aim of the article is to highlight the importance of aligning the 3D documentation strategy to the archaeological aims, by detailing all factors to be considered when deciding on one documentation strategy over another. The archaeological question discussed here, part of the PhD thesis of one of the co-authors (MP), relates to the Cypro-Minoan signatory and its diachronic variability. The 3D geometric characterization of signs and subsequent shape analysis is the method chosen to reach this goal. A major effort to be invested in correctly determining the shape and variability of each sign, is in assuring that the 3D captured shape is as close as possible to the archaeological reality, which is a common problem not only in palaeographical analysis but also in other fields, where features of interest are in the sub-millimetre range. The paper will illustrate how different data acquisition approaches and post-processing steps such as alignment methods and error treatment may distort the visualised result and thus have a negative impact on planned analysis. Thus, it will argue for the importance of more detailed paradata to allow an informed assessment of the reliability of 3D models and it proposes a list of values and decision-making steps that help make the 3D digitization process more robust and verifiable.
“Real Change Comes from Within!”: Towards a Symbiosis of Human and Digital Guides in the Museum
Authors: Antoniou Angeliki , Vayanou Maria , Katifori Akrivi , Chrysanthi Angeliki , Cheilitsi Filippia , Ioannidis Yannis
Published: December 2021

Extensive research on mobile guides for museums has explored the potential of technology to offer some of the services that have been traditionally provided by human guides, including guiding visitors in the museum space, providing information about the exhibits, and using more advanced interpretative approaches such as digital storytelling and gamified techniques. However, the majority of these approaches either ignores or tries to substitute entirely the role of the human guide. In this work, we present a user study with 10 experienced tour guides, currently working in the museum of modern art of the Basil & Elise Goulandris Foundation. Based on a three-phase procedure, the study is designed to empower professionals into envisaging their work in symbiosis with current technological developments. First, we attempt to identify existing challenges guides face and to capture their tacit knowledge in addressing emerging problems in guided tours. In the second and third stage, through a reflective and productive discussion, we employ a set of contemporary innovative digital applications as a starting point to elicit their views on their role in an envisaged symbiotic future of human-led hybrid digital experiences.
A Query Language for Workflow Logs
Authors: Tang Yan , Cui Weilong , Su Jianwen
Published: December 2021

A business process (workflow) is an assembly of tasks to accomplish a business goal. Real-world workflow models often demanded to change due to new laws and policies, changes in the environment, and so on. To understand the inner workings of a business process to facilitate changes, workflow logs have the potential to enable inspecting, monitoring, diagnosing, analyzing, and improving the design of a complex workflow. Querying workflow logs, however, is still mostly an ad hoc practice by workflow managers. In this article, we focus on the problem of querying workflow log concerning both control flow and dataflow properties. We develop a query language based on “incident patterns” to allow the user to directly query workflow logs instead of having to transform such queries into database operations. We provide the formal semantics and a query evaluation algorithm of our language. By deriving an accurate cost model, we develop an optimization mechanism to accelerate query evaluation. Our experiment results demonstrate the effectiveness of the optimization and achieves up to 50× speedup over an adaption of existing evaluation method.
Meta-Analysis of Factors Associated with Occupational Therapist Burnout
Authors: Park Eun-Young
Published: December 2021

Burnout, a reaction to chronic emotional stress, affects health and reduces the quality of service. Reportedly, healthcare professionals are especially vulnerable to burnout. This meta-analysis is aimed at examining the factors associated with occupational therapists’ burnout. The results of 2,430 occupational therapists, across 17 peer-reviewed English articles, the most recent published in 2020, were analysed. Results revealed significant associations between related variables and burnout. Marital status, work field, and work hours, job challenges, patient age, position, turnover intention, working type, and work addiction showed significant positive correlation effect sizes in relation to burnout, whereas age, education, engagement, job satisfaction, personal identity, professional identity, rewards, and feeling valued showed significant negative correlation effect sizes. The results of this meta-analysis suggest that strategies to reduce occupational therapists’ burnout need to consider organizational as well as psychological aspects.
A Fast Postprocessing Algorithm for the Overlapping Problem in Wafer Map Detection
Authors: Li Yang , Wang Jianguo
Published: December 2021

Mixed defects have become increasingly popular in defect detection and one of the hottest research areas in wafer maps. Postprocessing methods used to solve the overlapping problem in mass mixed defects have a poor detection speed, which is insufficient for rapid defect detection. In this paper, the fast‐soft nonmaximum suppression (fs‐NMS) method is proposed to solve this problem. The score of the detection box is updated by optimizing the penalty distribution function. Further, this paper analyzes the performance of the fs‐NMS method in wafer defect detection. As a penalty, the logistic function is used, and experiments are conducted using single‐stage and two‐stage detectors. The final results show that, compared to the soft‐NMS, the efficiency for the single‐stage and two‐stage detectors is increased on average by 9.63% and 21.72%, respectively.
Advances in an Event-Based Spatiotemporal Data Modeling
Authors: Zhu Xinming , Liu Haiyan , Xu Qing , Liu Jun’nan , Lihua Xiaoyang
Published: December 2021

Spatiotemporal data are vitally important for the national economy and defense modernization since it is not only an important component of human society and geographical information of the environment but also a key carrier of spatiotemporal information. An event-based spatiotemporal data model and its improvements are employed to model spatiotemporal objects, change history, and change relation, which is the main approach to resolve the spatiotemporal change modeling and has been comprehensively developed in modeling theory and applications. This manuscript studies the event-based spatiotemporal data modeling theory based on three aspects of the cognitive theory, which are the spatiotemporal object, the concept of the spatiotemporal dynamic object, and the spatiotemporal object relationship. Then, the implementation characteristics of the models were analyzed regarding the management of cadastral information, analog natural disaster phenomena, and reasoning. Finally, the key points and difficulties of an event-based spatiotemporal data modeling and prospective developmental trends were discussed to provide insights with spatiotemporal data modeling.
circABCB10 Promotes Malignant Progression of Gastric Cancer Cells by Preventing the Degradation of MYC
Authors: Zhang Yingchun , Zhou Yong , Wei Fang
Published: December 2021

Objective. To investigate the role of circABCB10 in gastric cancer and the molecular mechanism of promoting malignant progression of gastric cancer cells by preventing the degradation of MYC by hsa-miR-1252-5p. Methods. The expression of circABCB10 in gastric cancer tissues and cells was detected by real-time quantitative PCR. MTT, Transwell, clone formation, and TUNEL assay were used to detect the effects of circABCB10 on the proliferation, invasion, and apoptosis of gastric cancer cells. A subcutaneous tumor-bearing model was established to study the inhibitory effect of knockdown circABCB10 on gastric cancer proliferation. The dual luciferase reporter gene assay and RNA pull-down assay were used to verify the regulatory effect of circABCB10 on miR-1252-5p and the regulatory effect of miR-1252-5p on MYC. Results. Compared with paracancerous tissues and gastric mucosal epithelial cells, the expression of circABCB10 was significantly increased in human gastric cancer tissues and gastric cancer cells. circABCB10 knockout significantly decreased cell viability and invasion ability and promoted cell apoptosis (

P
<
0.01

). Subcutaneous tumor-bearing experiments in nude mice demonstrated that circABCB10 knockdown inhibited the proliferation of gastric cancer cells. circABCB10 can act as a sponge for miR-1252-5p in gastric cancer cells. Meanwhile, MYC is the target gene of miR-1252-5p. Overexpression of miR-1252-5p and knockdown of MYC reversed the promoting effect of circABCB10 on gastric cancer. Conclusion. circABCB10 can promote the proliferation, invasion, and clonal formation of gastric cancer cells by targeting miR-1252-5p and upregulating the expression of MYC. circABCB10/miR-1252-5p/MYC constitutes the regulatory mechanism of ceRNA.
Dynamic Characteristics of Four Systems of Difference Equations with Higher Order
Authors: Khan Abdul Qadeer , Qureshi Shahid Mahmood , Ahmed Imtiaz
Published: December 2021

In this paper, we explore the global dynamical characteristics, boundedness, and rate of convergence of certain higher-order discrete systems of difference equations. More precisely, it is proved that for all involved respective parameters, discrete systems have a trivial fixed point. We have studied local and global dynamical characteristics at trivial fixed point and proved that trivial fixed point of the discrete systems is globally stable under respective definite parametric conditions. We have also studied boundedness and rate of convergence for under consideration discrete systems. Finally, theoretical results are confirmed numerically. Our findings in this paper are considerably extended and improve existing results in the literature.
Weighted Norm Inequalities for Multilinear Fourier Multipliers with Mixed Norm
Authors: Fujita Mai
Published: December 2021

In this paper, weighted norm inequalities for multilinear Fourier multipliers satisfying Sobolev regularity with mixed norm are discussed. Our result can be understood as a generalization of the result by Fujita and Tomita by using theLr-based Sobolev space,1<r≤2with mixed norm.
Optimized Algebraic Reconstruction Algorithm Based Hemodynamic Changes in Color Doppler Ultrasound in Monitoring the Patients with Colorectal Cancer Undergoing Peripherally Inserted Central Catheter and Catheterization Nursing
Authors: Yu Miao , Li Junhui , Li Yue , Yu Lejing
Published: December 2021

The purpose of this study was to analyze the hemodynamic changes and nursing care of patients with colorectal cancer who were peripherally placed into the central venous catheter (PICC) by color Doppler ultrasound based on an optimized algebraic reconstruction (ART) (OART) algorithm. In this study, 150 patients with colorectal cancer were selected and randomly divided into observation group and control group, with 75 cases in each group. Different nursing interventions were carried out. An optimized algebraic reconstruction (OART) algorithm was proposed, and the traditional ART algorithm and filtered back-projection (FBP) algorithm were introduced for comparison. They were applied in ultrasounds of 150 colorectal cancer patients undergoing PICC. The results showed that the Dice coefficient (Dice) and peak signal-to-noise ratio (PSNR) of the OART algorithm were greater than those of the ART and FBP algorithms, while the difference function (DF) and the running time were opposite (

P

 < 0.05). The blood flow velocity (BFV) and blood flow (BF) of the arm vein 5 days after puncture were the least, which were less than those before puncture and 10 days and 30 days after puncture (

P

 < 0.05). Thrombosis was most likely to be found 4–6 days after puncture (28 cases), followed by 10–15 days after puncture (22 cases), and one day after the puncture (19 cases). The BFV and BF of patients with thrombosis were lower than those of patients without thrombosis (

P

 < 0.05). The total infection rate of PICC in the observation group was 10.7%, which was lower than that in the control group 32.0%,

P

 < 0.05. Nursing satisfaction of patients in observation group and control group was 95.99% and 75.99%, respectively,

P

 < 0.05, and the difference was statistically significant. In short, the ORAT algorithm proposed had better performance than the traditional algorithms in ultrasound image reconstruction; strengthening nursing intervention for chemotherapy patients with colorectal cancer undergoing PICC could effectively reduce the infection rate of PICC and improve the nursing satisfaction of patients.
Barcode Location in Financial Statement System Based on the Partial Differential Equation Image Recognition Algorithm
Authors: Ning Jinghua , Yu Song
Published: December 2021

Financial statements are the basis of financial analysis. Most of them are still using traditional financial statement software, and financial data cannot achieve better information sharing. Using a barcode to improve the efficiency of data sharing is undoubtedly the most convenient and fast way to realize financial statement information sharing. This paper studies the problem of the barcode image location and recognition in the financial statement system and tries to apply the partial differential equation image recognition algorithm to the barcode location in the financial statement system. In this paper, image technology is used to preprocess the code 39 barcode label image in the captured image, including color space conversion, image enhancement, threshold segmentation, binarization, and edge detection. The barcode position location is realized by using the method based on integral projection peak analysis and Hough transform line detection. It is proved that the positioning function of the barcode makes the data in financial statements realize resource sharing. Then, the performance of the completed barcode positioning and recognition algorithm is tested. The reliability and effectiveness of the algorithm are verified on the manually made test set.
A Steep Early Learning Curve for Endoscopic Submucosal Dissection in the Live Porcine Model
Authors: Küttner-Magalhães Ricardo , Dinis-Ribeiro Mário , Bruno Marco J. , Marcos-Pinto Ricardo , Rolanda Carla , Koch Arjun D.
Published: December 2021

Background: Endoscopic submucosal dissection (ESD) is a demanding procedure requiring high level of expertise. ESD training programs incorporate procedures with live animal models. This study aimed to assess the early learning curve for performing ESD on live porcine models by endoscopists without any or with limited previous ESD experience. Methods: In a live porcine model ESD workshop, number of resections, completeness of the resections, en bloc resections, adverse events, tutor intervention, type of knife, ESD time and size of resected specimens were recorded. ESD speed was calculated. Results: A total of 70 procedures were carried out by 17 trainees. The percentage of complete resections, en bloc resections and ESD speed increased from the first to the latest procedures (88.2%–100%, 76.5%–100%, 8.6–31.4 mm2/min, respectively). The number of procedures in which a trainee needed tutor intervention and the number of adverse events also decreased throughout the procedures (4 to 0 and 6 to 0, respectively). During the workshop, when participants changed to a different type of knife, ESD speed slightly decreased (18.5 mm2/min to 17.0 mm2/min) and adverse events increased again (0–2). Conclusions: Through successive procedures, complete resections, en bloc resections, and ESD speed improve whereas adverse events decrease, supporting the role of the live porcine model in the preclinical learning phase. Changing ESD knives has a momentarily negative impact on the learning curve.
КЛІНІКО-ЛАБОРАТОРНА ХАРАКТЕРИСТИКА ЛЕТАЛЬНИХ ВИПАДКІВ ВІД ПАНДЕМІЧНОГО ГРИПУ А/H1N1 ПОРІВНЯНО З ТЯЖКИМИ ФОРМАМИ COVID-19
Authors: Юрко К. В. , Кацапов Д. В. , Бондаренко А. В. , Нартов П. В. , Максуль Т. Є. , Харченко О. М.
Published: December 2021

У поточному епідемічному сезоні продовжується циркуляція вірусів грипу, зокрема А – A(H3N2) та A(H1N1)pdm09, а також вірусу грипу В, переважно (98 %) лінії B/Victoria. За даними центру Громадського здоров’я МОЗ України, рівень щеплення проти грипу залишається низьким, становлячи близько 0,6 % населення України, а серед груп професійного та епідемічного ризику – 22,8 %. У сучасних умовах одночасна циркуляція вірусів грипу та SARS-CoV-2 може призвести до труднощів диференційної діагностики та лікування.
Мета роботи – порівняння клініко-лабораторних особливостей тяжкого перебігу грипу, ускладненого пневмонією, спричиненого пандемічним вірусом грипу A(H1N1) pdm09 в епідемічному сезоні 2015/2016 років із COVID-19.
Пацієнти і методи. Проведено аналіз клінічних симптомів і даних лабораторного обстеження 19 хворих на грип, ускладнений негоспітальною пневмонією ІV клінічної групи, які перебували на лікуванні в ОКІЛ м. Харкова, та їх порівняння з такими у хворих на COVID-19 за даними літератури.
Результати досліджень та їх обговорення. Серед досліджених хворих переважали чоловіки – 12 осіб (63,2 %) віком (50,7±11,9) років. Більшість мала супутні захворювання. На початку захворювання переважали помірна слабкість, головний біль, фебрильна температура, незначні катаральні явища, у зв’язку з чим ушпиталення затримувалось. Із 3-4-ї доби недуги стан суттєво погіршувався, приєднувались задишка, ціаноз. Типовими початковими симптомами COVID-19 були гарячка різного ступеня (73 %), непродуктивний кашель (59 %) та задишка або відчуття нестачі повітря, що швидко прогресувало. Важливу роль у ранній діагностиці тяжких форм COVID-19 відіграє комп’ютерна томографія легень.
Висновки. У хворих на COVID-19 та тяжкий грип спостерігається здебільшого гострий початок захворювання, який супроводжувався помірною слабкістю, головним болем та гарячкою до 38 °С. Ураження верхніх дихальних шляхів характеризувалось симптомами фарингіту. При грипі відбувається затримка звернення за медичною допомогою та ушпиталення на (6,2±1,5) добу від початку захворювання. Тяжкість грипу зумовлена приєднанням негоспітальної пневмонії, на відміну від COVID-19, де типовими ознаками є дифузне, переважно субплевральне ураження легень. Для запобігання тяжкому ускладненому перебігу грипу, спричиненого пандемічним вірусом A/H1N1pdm в умовах пандемії COVID-19 необхідна вакцинація осіб із груп ризику до початку епідемічного сезону.
НЕЙРОІМУННІ ЗМІНИ В РАННІЙ ДІАГНОСТИЦІ ВІЛ-ІНФЕКЦІЇ
Authors: Чемич М. Д. , Сосновенко Д. С. , Янчук С. М.
Published: December 2021

Мета – вивчення впливу нейроспецифічних білків на розвиток нейро-СНІДу, встановлення перспектив їх визначення з метою ранньої діагностики ВІЛ-інфекції.
У дослідженні використовували теоретичні методи, які включали аналіз та синтез вивчення сучасних світових наукових публікацій та клінічних спостережень, дедуктивно-індуктивні методи.
Висновки. В Україні, як і у всьому світі, відбувається активне поширення та пізнє виявлення ВІЛ-інфекції. Стандартні методи лабораторної діагностики не можуть забезпечити якісну ранню діагностику хвароби.
Швидке проникнення вірусу у центральну нервову систему (ЦНС) створює труднощі для диференційної діагностики з подальшим формуванням стійкості до антиретровірусних препаратів. Поки ВІЛ у крові залишається протягом тривалого прихованого періоду, збудник активно реплікується у клітинах мозку і призводить до розвитку нейро-СНІДу.
Зв’язки та особливості накопичення матриксу ВІЛ-білка р-17 у ЦНС, активність транскрипційного трансактиватора, регуляторного білка Vpr залишаються недостатньо вивченими. Нейроспецифічні білки як маркери вірусного патологічного процесу у нервовій системі людини потребують особливої уваги та вивчення.
Перегляд основ ранньої діагностики ВІЛ-інфекції дасть можливості посилити епідеміологічний контроль та запобігати новим випадкам хвороби, що у підсумку приведе до зменшення фінансового навантаження щодо цієї проблеми не лише в Україні, а й у багатьох країнах світу.
ОКИСНА ДЕСТРУКЦІЯ БІЛКІВ ПРИ ГІПОКСИЧНО-ІШЕМІЧНИХ УРАЖЕННЯХ ГОЛОВНОГО МОЗКУ НА ЕТАПАХ КАРДІОХІРУРГІЧНИХ ВТРУЧАНЬ З ВИКОРИСТАННЯМ ШТУЧНОГО КРОВООБІГУ
Authors: Маньковський Д. С.
Published: December 2021

Роль вільнорадикального окиснення білків крові в механізмах розвитку гіпоксично-ішемічних уражень (ГІУ) головного мозку (ГМ) та у ефективності функціонування гематоенцефалічного бар’єру (ГЕБ) залежить від ендотеліальних клітин, астроцитів і перицитів, порушення функцій яких викликає дисфункцію ГЕБ, зокрема за рахунок окиснення білкових фрагментів.

Мета – вивчення особливостей окиснення білкових фрагментів клітин та нуклеїнових кислот у пацієнтів з гіпоксично-ішемічними ураженнями до та після кардіохірургічних втручань з використанням штучного кровообігу.

Матеріал і методи. Наведені результати обстеження 38 пацієнтів з гіпоксично-ішемічними ураженнями головного мозку після кардіохірургічних втручань; діагностику неврологічного статусу виконували згідно з клінічними протоколами. Метаболічні зміни щодо окисної модифікації білків (ОМБ) та нуклеїнових кислот (ОМНК) досліджено у спонтанних та індукованих (Fe++) реакціях на доопераційному (за 3–5 діб) та післяопераційному (через 5–7 діб) етапах. Вивчено вміст білкових компонентів у сироватці крові – 2,4 – динітрофенілгідрозонів (ДНФГ).

Результати. Спонтанна ОМБ на етапах КХВ характеризується достовірними (р<0,001) змінами у накопиченні як альдегідних, так і карбонільних продуктів, а також у зміні ступеня (глибини) деструкції білків. В індукованих реакціях ОМБ виявлено зростання (з (0,303±0,007) у.о./мг білка до (0,396±0,003)у.о./мг білка) ступеня (глибини) деструкції білка за рахунок білкових фрагментів середнього розміру та достовірного збільшення питомої ваги фрагментів малого розміру, що є найінформативнішою ознакою впливу на метаболічні резерви ОМБ у хворих.

Висновки. На етапах кардіохірургічного втручання формуються передумови, що сприяють інтенсифікації процесу ОМБ плазми крові та ОМНК. Особливістю змін стану ОМНК та ОМБ є найбільш виразне зростання їх вмісту в післяопераційний період на тлі відносного зростання вмісту альдегідних та карбонільних продуктів окиснення з перерозподілом ступеня (глибини) ОДБ в спонтанних та, особливо, в індукованих реакціях. Наведене свідчить про зростання проявів деструкції та інтенсифікації ОМБ при одночасному накопиченні резервів окиснення білкових фрагментів плазми крові в післяопераційному періоді.
OPTIMIZATION OF OPERATIVE DELIVERY OF WOMEN IN LABOR WITH PLACENTA PREVIA
Authors: Zhelezov D. M.
Published: December 2021

The aim – to evaluate the effectiveness of preventive ligation of uterine vessels during caesarean section in women with placenta previa.

Material and Methods. The study was conducted on the basis of the Regional Perinatal Center and Maternity Hospital № 5 (Odessa) for 2000–2020 and performing the main stage of cesarean section after reducing perfusion in the placenta. Uterine ligation was performed after fetal removal. The volume of blood loss, the condition of the mother and fetus were monitored, and perinatal results were analyzed.

Statistical processing was performed by methods of variance and frequency analysis using Statistica 13.0 software (TIBCO, USA).

Results. The mean age of pregnant women was 33.4±1.2 years. The clinic of placenta previa during pregnancy was extremely scanty. As a rule, the diagnosis was made during ultrasound monitoring. In 16 (17.7 %) there was repeated bleeding from the genital tract without pain and increased uterine tone, with the development of anemia of moderate severity. Single bleeding was observed in 53 (58.9 %) women.

Blood loss was 1380±112 ml in group I, 466±34 ml in group II (p<0.05). The frequency of anemia in the postoperative period was 38.0 % and 17.5 %, respectively (p<0.05). All newborns were discharged on the 5-7th day of the postpartum period in satisfactory condition. There were no cases of distress syndrome.

Conclusions: 1. The method of control of blood loss during placenta previa by ligation of the uterine arteries is effective – blood loss was in group I 1380±112 ml, in group II – 466±34 ml (p<0,05). 2. The frequency of anemia in the postoperative period was 38.0 in group I and 17.5 % in group II (p<0.05).
“Clinging Stubbornly to the Antithesis of Assumptions”: On the Difference Between Hegel’s and Spinoza’s Systems of Philosophy
Authors: Smith Daniel J.
Published: December 2021

This essay re-examines Hegel’s critique of Spinoza’s Ethics, focusing on the question of method. Are the axioms and definitions unmotivated presuppositions that make the attainment of absolute knowledge impossible in principle, as Hegel charges? This essay develops a new reading of the Ethics to defend it from this critique. I argue that Hegel reads Spinoza as if his system were constructed only according to the mathematical second kind of knowledge, ignoring Spinoza’s clear preference for knowledge of the third kind. The Ethics, I argue, is a book with several layers: it is at once a deductive mathematical system, and a handbook to aid the intuitive power of the active philosophical reader. The letter of each text may be identical, but they have little else in common – Pierre Menard’s rewriting of Don Quixote given systematic philosophical form.
Where Is Negation in Merleau-Ponty’s Ontology? Symbolic Formation and the Implex
Authors: Kaushik Rajiv
Published: December 2021

This paper concerns a basic ambiguity in Merleau-Ponty’s ontology between the reversibility of flesh and its écart. Where the former suggests continuity between the sensing and the sensible, the latter suggests their separation. It is difficult to know from reading The Visible and the Invisible which is to be prioritized or how one is to be read alongside the other. I argue that such a relation comes to light by thinking through the negation that is, for Merleau-Ponty, always constellated with being. This becomes more explicitly an ontology of differentiation or difference itself which does not prioritize identity. Such an ontology is, I argue, prefigured in Merleau-Ponty’s work on passivity and its symbolic formation. The idea is that the dynamic between negation and being and of symbolic formation happens at the level of, or even in, the body. The final section is thus a consideration of “the implex,” a term Merleau-Ponty borrows from Paul Valéry along with “chiasm.”
Divining: ΥΔΩΡ, Opacity, and Thalean Considerations
Authors: Spitzer D. M.
Published: December 2021

Dowsing, water-witching, divining – the procedure seeks a flow or spring beneath the surface of earth. So too this inquiry attempts to locate and sound the meanings associated with the polestar of Thalean considerations, ὕδωρ, that course beneath the interpretative strata of an overly-familiar tradition grounded in the principles of clarity and intelligibility. If these principles are held in suspension, what meanings flow from the Thalean considerations of ὕδωρ? A twofold task guides this inquiry. First is to show opacity as the primary valence of ὕδωρ, challenging the prevailing tendency to imagine Thales and other Milesian thinkers as positing a principle of clarity in the form of what can be brought under the Aristotelean concept of underlying thing and matter (ὕλη). Second, in the course of drawing up the opacity of ὕδωρ form varied archaic sources emerge some connections to important terms for Greek thinking: φύσις, λόγος, ἀλήθεια.
The Spirit in the Book of Psalms
Authors: Martin Lee Roy
Published: December 2021

This survey of the Spirit’s activity in the book of Psalms examines six prominent texts in which the word “spirit” (‮רוח‬‎) appears (Psalms 18, 51, 104, 139, 142, and 143). The study of these texts suggests that the Spirit is described in the Psalter as the agent of God’s life-giving power and as the administrator of God’s moral authority. As the agent of God’s life-giving power, the Holy Spirit creates all life and sustains all life. As administrator of God’s moral authority, the Holy Spirit saves, guides, sanctifies, and enacts judgment.
The Spirit in Isaiah
Authors: Ma Wonsuk
Published: December 2021

This study employs an “elect” concept to frame the diverse nature and work of the Spirit in Isaiah. God created humans in his image and enlivened them by his to “rule over” the whole of creation. This makes God’s elect a “charismatic” figure: chosen or called to be his possession and to stand between God and the recipients of the elect’s ministry, and to perform God-given tasks with his enduring and equipping presence through the Spirit. For the “tasks,” the Spirit equips or empowers the elected entity. However, the book of Isaiah also contains references to the Spirit without a human agent, revealing God’s character and work. This study will examine key passages of the Spirit in Isaiah to identify the Spirit’s role over the recipients with a focus on its “charismatic” function upon the “elect.”
The Spirit in Ephesians and Philippians
Authors: Darko Daniel K.
Published: December 2021

This study aims to shed light on the richness, essence, and range of πνεῦμα lexemes in Paul’s correspondence to Christ followers in Western Asia Minor and Roman Philippi. I will endeavor to show the import of each occurrence of πνεῦμα or its cognate in these letters and provide a synthesis of the findings at the conclusion. It will become apparent that Paul does not have one consistent referent for πνεῦμα, either to the Holy Spirit or to other spiritual activities. The study will also show that Paul’s use of πνεῦμα lexemes is predicated upon the occasion and provenance of the letter in question. The analysis begins with Ephesians due to its higher frequency and range of πνεῦμα usage compared to its five appearances in Philippians.
Breaking Bread with the Bedchamber
Authors: Ng Jennifer S.
Published: December 2021

This article examines the institution of the Bedchamber of James I of England (1603–1625) through the practice of feasting. Originally comprising James VI’s Scottish entourage, the Bedchamber was a novel introduction to the English royal household in the Jacobean period: as such, this group of attendants came to represent both a body with unparalleled royal access, and a Scottish barrier between James I and his English court. By approaching the Bedchamber through its social and cultural obligations, the institution emerges as a mediating, rather than restrictive, body, serving to enact reconciliation between the king, the Court, and foreign states. Moreover, the Bedchamber’s feasting calendar indicates a broad basis of reward, circulating around several Bedchamber Gentlemen rather than a single favorite. Patterns of Bedchamber feasting ultimately reflected a Court that was largely accessible, not significantly structured by ethnic divisions, and conducive to the proliferation of culture and favor.
A new insect (probably basal Odonatoptera) from the Pennsylvanian (Late Carboniferous) of the Piesberg Fossil-Lagerstätte, Osnabrück, Germany
Authors: ZESSIN WOLFGANG , BRAUCKMANN CARSTEN , GRÖNING ELKE
Published: December 2021

The rich Pennsylvanian (Late Carboniferous; Moscovian, Westphalian D/Asturian) insect fauna of the large Piesberg quarry N Osnabrück, Lower Saxony, Germany with hitherto more than 1,300 registered specimens shows a great diversity. It includes palaeopterous (more than 20 specimens of Odonatoptera, and a number of Palaeodictyoptera) as well as neopterous insects (far more than 1,000 specimens). Only a smaller part has already been described, and the research is still continuing.
The Kiandra leek orchid is the previously presumed extinct mignonette leek orchid (Orchidaceae; Orchidoideae): evidence from morphological comparisons
Authors: AYRE BRONWYN M. , HAYASHI TOBIAS , PHILLIPS RYAN D. , REITER NOUSHKA
Published: December 2021

Prasophyllum morganii (Orchidaceae), the mignonette leek orchid, was first collected from a single population in the subalps of Victoria, Australia, in 1929 but has not been collected since 1933. A morphologically similar leek orchid, P. retroflexum, was described in 2000 from Kosciuszko National Park, New South Wales, Australia. We measured 51 morphological traits on 14 field collected and 13 herbarium specimens of P. retroflexum, and six historical herbarium collections of P.  morganii. In addition, we conducted a comparison of the types of both species with the field and herbarium specimens. Multivariate analyses were undertaken using 35 characters, and an ordination performed on range-standardised data. Results show no morphological differences between specimens identified as P. morganii and P. retroflexum, and we conclude they are conspecific.
Diospyros xylocarpa, a New Species of Ebenaceae from China and Vietnam
Authors: SIMA YONG-KANG , CHEN WEN-HONG , WU JIAN-YONG , SHUI YU-MIN
Published: December 2021

A new species of Ebenaceae, Diospyros xylocarpa Y. M. Shui, W. H. Chen & Sima, from China and Vietnam, is described and illustrated. The new species is similar to D. phuketensis Phengklai, but differs in its bigger and densely ochre brown villous leaves, more pairs of lateral veins, shorter petioles, 8-locular ovaries, xyloid fruits with nearly square fruiting calyx and much shorter fruiting peduncle and eight seeds. The new species is also similar to D. dasyphylla Kurz, but differs in its leaf blades with a cuneate to round base, eight stamens and bigger and xyloid fruits.
Rediscovery and supplemental description of Begonia hymenophylloides (Begoniaceae) as new record in China
Authors: TIAN JING , WANG YAN , REN JING , PENG SHUAI , WANG JUN-JIE , ZHANG CAI-FEI , HU GUANG-WAN
Published: December 2021

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Scene terrain classification for autonomous vehicle navigation based on semantic segmentation method
Authors: Julius Fusic S , Hariharan K , Sitharthan R , Karthikeyan S
Published: December 2021

Autonomous transportation is a new paradigm of an Industry 5.0 cyber-physical system that provides a lot of opportunities in smart logistics applications. The safety and reliability of deep learning-driven systems are still a question under research. The safety of an autonomous guided vehicle is dependent on the proper selection of sensors and the transmission of reflex data. Several academics worked on sensor-based difficulties by developing a sensor correction system and fine-tuning algorithms to regulate the system’s efficiency and precision. In this paper, the introduction of vision sensor and its scene terrain classification using a deep learning algorithm is performed with proposed datasets during sensor failure conditions. The proposed classification technique is to identify the mobile robot obstacle and obstacle-free path for smart logistic vehicle application. To analyze the information from the acquired image datasets, the proposed classification algorithm employs segmentation techniques. The analysis of proposed dataset is validated with U-shaped convolutional network (U-Net) architecture and region-based convolutional neural network (Mask R-CNN) architecture model. Based on the results, the selection of 1400 raw image datasets is trained and validated using semantic segmentation classifier models. For various terrain dataset clusters, the Mask R-CNN classifier model method has the highest model accuracy of 93%, that is, 23% higher than the U-Net classifier model algorithm, which has the lowest model accuracy nearly 70%. As a result, the suggested Mask R-CNN technique has a significant potential of being used in autonomous vehicle applications.
A Social Network Analysis–based approach to investigate user behaviour during a cryptocurrency speculative bubble
Authors: Bonifazi Gianluca , Corradini Enrico , Ursino Domenico , Virgili Luca
Published: December 2021

In this article, we present a Social Network Analysis–based approach to investigate user behaviour during a cryptocurrency speculative bubble in order to extract knowledge patterns about it. Our approach is general and can be applied to any past, present and future cryptocurrency speculative bubble. To verify its potential, we apply it to investigate the Ethereum speculative bubble happened in the years 2017 and 2018. We also describe several interesting knowledge patterns about the behaviour of specific categories of users that we obtained from this investigation. Furthermore, we describe how our approach can support the construction of an identikit of the speculators who maneuvered behind the Ethereum bubble analysed. Finally, we show that this capability of supporting the hunting for speculators is intrinsic of our approach and can cover past, present and future bubbles.
Levels of endoplasmic reticulum stress-related mRNA in peritoneal fluid of patients with endometriosis or gynaecological cancer
Authors: Yeo Seung Geun , Lee Sung Jong , Lee Ji Woo , Oh Sujung , Park Dong Choon
Published: December 2021

Objective

To compare the levels of endoplasmic reticulum (ER) stress-associated mRNAs and the clinical characteristics of patients with endometriosis or gynaecological cancer.

Methods

This prospective study obtained intraperitoneal fluid samples from female patients that underwent surgery. The levels of ER stress mRNAs in the peritoneal fluid, including C/EBP-homologous protein (CHOP), X-box binding protein 1 (sXBP1), activating transcription factor 6 (ATF6), immunoglobulin heavy chain-binding protein (BiP), inositol-requiring enzyme 1α (IRE1α) and protein kinase RNA-like endoplasmic reticulum kinase (PERK), were measured using real-time reverse transcription–polymerase chain reaction in patients with benign disease without endometriosis (control group), with endometriosis or with gynaecological cancer.

Results

This study enrolled 126 patients: 46 control patients; 47 with endometriosis; and 33 with cancer. The levels of CHOP and BiP mRNA were significantly higher in the control group compared with the cancer group. Levels of sXBP1 and ATF6 mRNA were significantly higher in the cancer group than in the control and endometriosis groups. In the endometriosis group, ATF6 mRNA level was inversely correlated with age and positively correlated with serum cancer antigen 125 levels; and ATF6 and PERK mRNA levels were inversely correlated with parity.

Conclusion

The levels of ER stress-related mRNAs were related to the pathogenesis of endometriosis and gynaecological cancers.
The Role of Indian Hedgehog Signaling in Tendon Response to Subacromial Impingement: Evaluation Using a Mouse Model
Authors: Liu Yulei , Deng Xiang-Hua , Zhang Xueying , Cong Ting , Chen Daoyun , Hall Arielle Jordan , Ying Liang , Rodeo Scott A.
Published: December 2021

Background:

The underlying cellular and molecular mechanisms involved in the development of tendinopathy due to subacromial supraspinatus tendon (SST) impingement and the response to subsequent removal of impingement remain unknown.

Purpose:

To investigate the involvement of Indian hedgehog (IHH) signaling in the development of SST tendinopathy and the subsequent healing process after the relief of subacromial impingement in a novel mouse shoulder impingement model.

Study Design:

Controlled laboratory study.

Methods:

A total of 48 male wild-type C57BL/6 mice were used in this study. Supraspinatus tendinopathy was induced by inserting a microsurgical clip into the subacromial space bilaterally. Eleven mice were sacrificed at 4 weeks after surgery to establish impingement baseline; 24 mice underwent clip removal at 4 weeks after surgery and then were euthanized at 2 or 4 weeks after clip removal. Thirteen mice without surgical intervention were utilized as the control group. All SSTs were evaluated with biomechanical testing; quantitative histomorphometry after staining with hematoxylin and eosin, Alcian blue, and picrosirius red; and immunohistochemical staining (factor VIII, IHH, Patched1 [PTCH1], and glioma-associated oncogene homolog 1 [GLI1]).

Results:

The mean failure force and stiffness in the 4-week impingement group decreased significantly compared with the control group ( P < .001) and gradually increased at 2 and 4 weeks after clip removal. Histological analysis demonstrated increased cellularity and disorganized collagen fibers in the SST, with higher modified Bonar scores at 4 weeks, followed by gradual improvement after clip removal. The IHH-positive area and PTCH1- and GLI1-positive cell percentages significantly increased after 4 weeks of clip impingement (20.64% vs 2.06%, P < .001; 53.9% vs 28.03%, P = .016; and 30% vs 12.19%, P = .036, respectively) and continuously increased after clip removal.

Conclusion:

The authors’ findings suggest that the hedgehog signaling pathway and its downstream signaling mediator and target GLI1 may play a role in the development and healing process of rotator cuff tendinopathy due to extrinsic rotator cuff impingement.

Clinical Relevance:

This study suggests the potential for the hedgehog pathway, together with its downstream targets, as candidates for further study as potential therapeutic targets in the treatment of supraspinatus tendinopathy.
Health Care Professionals’ Experiences of Facilitating Patient Activation and Empowerment in Chronic Illness using a Person-Centered and Strengths-Based Self-Management Program
Authors: Heggdal Kristin , Stepanian Natalie , Oftedal Bjørg Frøysland , Mendelsohn Joshua B. , Larsen Marie Hamilton
Published: December 2021

Objective

Patients with chronic illness who are empowered and activated are more likely to engage in self-management in order to stabilise their condition and enhance their quality of life. This study aimed to explore Health Care Professional's (HCP) assessment of a person-centered intervention called ‘The Bodyknowledging Program’ (BKP) for the facilitation of empowerment and patient activation in the context of chronic illness.

Methods

This study employed a qualitative process evaluation after programme completion. Data was collected through focus-groups and individual interviews with HCPs and content analysis was used in the analysis.

Results

Four themes were identified: 1) Shifts towards the patient-perspective, 2) The value of a patient-centered conceptual framework, 3) Patient activation through dialogue based support and 4) Challenging competencies. Discussion: This study introduces ‘The Bodyknowledging Program’ as a useful tool to uncover patients’ needs and to activate and empower them to take more responsibility for their health through self-care management. The usability of the new intervention depends on HCP's ability to develop their counselling skills and changing their approach towards utilising patients’ individual resources in the promotion of their health.
Clinical features of severe fever with thrombocytopenia syndrome and analysis of risk factors for mortality
Authors: He Feng , Zheng Xinxin , Zhang Zhaoru
Published: December 2021

Background

To understand the clinical characteristics of and explore the risk factors for mortality in patients with severe fever with thrombocytopenia syndrome (SFTS).

Methods

Data from SFTS patients diagnosed by laboratory examination at Chaohu Hospital affiliated with Anhui Medical University from June 2017 to January 2021 were retrospectively analysed. According to the clinical results, all confirmed patients were divided into the surviving group (80 patients) and non-surviving group (20 patients). The two groups were compared in terms of general characteristics, clinical symptoms and signs, laboratory indicators and other aspects. The independent risk factors for mortality in SFTS patients were analysed by multivariate binary logistic regression.

Results

Univariate analysis showed a significant difference in age and the incidence of consciousness disturbance, respiratory failure, haemorrhagic manifestations, renal dysfunction, shock, aspartate aminotransferase (AST) ≥400 U/L, creatine kinase (CK)≥1000 U/L, creatine kinase isoenzymes (CK-MB) ≥100 U/L, lactate dehydrogenase (LDH) ≥1000 U/L, serum creatinine ≥100 mmol/L, blood urea nitrogen ≥7.5 mmol/L and C-reactive protein ≥8 mg/L between the two groups (P < 0.05).

Conclusions

Consciousness disorder, haemorrhagic manifestations, renal dysfunction, AST ≥ 400 U/L, and LDH ≥ 1000 U/L are independent risk factors for mortality in SFTS patients and merit close attention in clinical treatment to avoid fatal consequences.