bluuebunny/crossref_metadata_2025 huggingface dataset:
Analisis Pengaruh Globalisasi terhadap Pertumbuhan Ekonomi di ASEAN Periode 2013-2019
Authors: Virgan Mikmayocha , Yanuar Yanuar
Published: May 2022

This study aims to determine the effect of Economic Globalization from a point of view of Economic Freedom, Trade Openness, and Foreign Direct Investment on Economic Growth. The research sample uses panel data across seven ASEAN countries which are Cambodia, Indonesia, Malaysia, Singapore, Thailand, Philippines, and Vietnam from 2013 to 2019. This research method uses Multiple Linear Regression (MLR) with Fixed Effect Model (FEM) on Eviews 9.0. The result of this study explains that there is a positive and significant effect of Trade Openness on Economic Growth, while there is no significant effect between Economic Freedom and Foreign Direct Investment on Economic Growth. Penelitian ini bertujuan untuk mengetahui pengaruh Globalisasi Ekonomi dari sudut pandang Kebebasan Ekonomi, Keterbukaan Perdagangan, dan Penanaman Modal Asing terhadap Pertumbuhan Ekonomi. Sampel penelitian menggunakan data panel di tujuh negara ASEAN yaitu Kamboja, Indonesia, Malaysia, Singapura, Thailand, Filipina, dan Vietnam dari tahun 2013-2019. Metode penelitian ini menggunakan Regresi Linear Berganda dengan Fixed Effect Model (FEM) pada program Eviews 9.0. Hasil penelitian ini menjelaskan bahwa Keterbukaan Perdagangan berpengaruh positif dan signifikan terhadap Pertumbuhan Ekonomi, sedangkan Kebebasan Ekonomi dan Penanaman Modal Asing tidak berpengaruh signifikan terhadap Pertumbuhan Ekonomi.
Pengaruh Performance Expectation, Effort Expectation, Social Influence, dan Facilitating Condition terhadap Behavioral Intention pada Pengguna ShopeePay di Jakarta
Authors: Kenny By Venansius , Firdausy Carunia Mulya
Published: May 2022

The behavioral intention of e-wallet users has increased significantly today. This study aims to analyze the influence of performance expectation, effort expectation, social influence, and facilitating conditions on the behavioral intention of ShopeePay users in Jakarta. Methods used to collect the data were by distributing questionnaires as an instrument to one hundred respondents who did their transactions by using ShopeePay in Jakarta. The data was then analyzed by applying the Partial Least Squares (PLS) statistical method. The result showed that the behavioral intention of users who used ShopeePay was influenced by performance expectation, effort expectation, social influence, and facilitating conditions. Therefore, the ShopeePay company needs to pay attention to these four variables to improve the behavioral intention of its users. Behavioral intention dari pengguna dompet digital telah meningkat secara signifikan saat ini. Penelitian ini bertujuan untuk menganalisis pengaruh performance expectation, effort expectation, social influence, dan facilitating condition terhadap behavioral intention pengguna ShopeePay di Jakarta. Metode yang digunakan untuk mengumpulkan data adalah dengan menyebarkan kuesioner sebagai instrumen kepada seratus responden yang melakukan transaksi dengan menggunakan ShopeePay di Jakarta. Data tersebut kemudian dianalisis dengan menggunakan metode statistik Partial Least Squares (PLS). Hasil penelitian menunjukkan bahwa behavioral intention pengguna yang menggunakan ShopeePay dipengaruhi oleh performance expectation, effort expectation, social influence, dan facilitating condition. Oleh karena itu, perusahaan ShopeePay perlu memperhatikan keempat variabel ini untuk meningkatkan behavioral intention penggunanya.
Pengaruh Covid-19 terhadap Pertumbuhan Fintech Pinjaman di Indonesia
Authors: Louise Louise , Yanuar Yanuar
Published: May 2022

COVID-19 pandemic affects every economic aspect globally, including the fintech P2P lending industry in Indonesia. Indonesia’s fast P2P lending fintech growth faces challenges during the COVID-19 pandemic. This study aims to detect whether there are significant differences in Indonesia’s fintech P2P lending growth before and during the COVID-19 pandemic, especially on these 5 variables: numbers of new customers, new investors, and amount of loan disbursement, TKB90 percentage, and amount of outstanding loan. Data analysis is done using paired T-test and Wilcoxon Signed Rank Test. This study concludes that there are significant differences between new borrower and the amount of loan disbursement before and during the COVID-19 pandemic, while there are no significant differences between new investors, TKB90 percentage, and amount of outstanding loans before and during the COVID-19 pandemic. Pandemi COVID-19 berdampak pada seluruh aspek perekonomian di dunia termasuk fintech pinjaman di Indonesia. Pertumbuhan fintech pinjaman di Indonesia yang begitu pesat dalam beberapa tahun ini kini memasuki tantangan baru di era pandemi COVID-19. Penelitian ini bertujuan untuk melihat apakah terdapat perbedaan signifikan pada pertumbuhan fintech pinjaman di Indonesia sebelum dan selama pandemi melalui lima variabel jumlah peminjam baru, pendana baru, penyaluran pinjaman, angka TKB90, dan jumlah pinjaman wanprestasi fintech pinjaman di seluruh Indonesia yang terdaftar dan memiliki izin OJK. Analisis data dilakukan menggunakan metode uji T dua sampel dependen dan uji Wilcoxon Signed Rank Test. Hasil penelitian menunjukkan bahwa terdapat perbedaan signifikan pada variabel jumlah peminjam baru dan penyaluran pinjaman sebelum dan selama pandemi COVID-19, dan tidak terdapat perbedaan signifikan pada variabel jumlah pendana baru, angka TKB90, dan jumlah pinjaman wanprestasi sebelum dan selama pandemi COVID-19.
Pengaruh Perceived Usefulness Services dan Self-efficacy terhadap Intention of Use Mobile Payment Fintech di Jakarta
Authors: Budiman Yohanes Imanuel
Published: May 2022

This study was conducted to identify if there is any influence between the perceived usefulness of services and self-efficacy towards the intention of using mobile payment fintech in Jakarta. This study uses primary data sources, with the research instrument used being a questionnaire. The sampling method used is non-probability sampling with purposive sampling technique, where the researcher set specific criteria to be used as samples in the study, namely people who live in Jakarta and have worked and then also have a mobile payment application and have used it for transactions. The research sample in this study was 300 active users of mobile payment services in DKI Jakarta. The method of analysis and processing of data was obtained using the SmartPLS 3.2.9 software. This study gives the results that the impact of perceived usefulness services on the intention of use is significant and there is also a significant impact of self-efficacy on the intention of use. Where in the results of this study, self-efficacy has a higher significant value on the intention of using mobile payment. Penelitian ini dilakukan untuk mengidentifikasi apakah ada pengaruh antara perceived usefulness services dan self-efficacy terhadap intention of use mobile payment fintech di Jakarta. Penelitian ini menggunakan sumber data primer, dengan instrumen penelitian yang digunakan yaitu kuesioner. Metode sampling yang digunakan adalah non-probability sampling dengan teknik purposive sampling, dimana peneliti menetapkan kriteria khusus untuk dijadikan sampel dalam penelitian yaitu masyarakat yang tinggal di Jakarta dan telah bekerja kemudian juga memiliki aplikasi mobile payment serta pernah menggunakannya untuk bertransaksi. Sampel penelitian dalam penelitian ini adalah 300 pengguna aktif layanan mobile payment di DKI Jakarta. Metode proses analisis dan pengolahan data yang diperoleh menggunakan software SmartPLS 3.2.9. Pada penelitian ini memberikan hasil bahwa dampak dari perceived usefulness services terhadap intention of use yang signifikan dan juga terdapat dampak yang signifikan dari self-efficacy terhadap intention of use. Dimana dalam hasil penelitian ini, self-efficacy memiliki nilai signifikasi yang lebih tinggi terhadap intention of use mobile payment.
Pengaruh Perceived Ease of Use dan Perceived Service Credibility terhadap Intention of Use Mobile Payment di Jakarta
Authors: Setiawan Setiawan
Published: May 2022

The purpose of this research is to identify the effect of Perceived Ease of Use and Perceived Service Credibility on the Intention of Use mobile payment in Jakarta. The data in this research was collected through a questionnaire method using Google Form. The sample used as many as 324 respondents the owner of bank accounts and mobile payment application users who live in Jakarta. The research results showed that there is a positive and significant implication between Perceived Ease of Use and Perceived Service Credibility towards Intention of Use Mobile Payment in Jakarta. Tujuan dari riset ini adalah untuk mengidentifikasi pengaruh antara Perceived Ease of Use dan Perceived Service Credibility terhadap Intention of Use mobile payment di Jakarta. Data dalam penelitian ini diambil dari metode kuesioner menggunakan Google Form. Sampel yang digunakan sebanyak 324 orang responden pemilik rekening bank dan pengguna aplikasi mobile payment yang tinggal di Jakarta. Penelitian ini menggunakan teknik analisis PLS (Partial Least Square). Hasil penelitian ini menunjukan adanya pengaruh positif dan signifikan antara Perceived Ease of Use dan Perceived Service Credibility terhadap Intention of Use mobile payment di Jakarta.
Aktivitas Antibakteri Ekstrak Bawang Hitam Variasi Waktu Aging Terhadap Pencegahan Dysbiosis Kulit Penyebab Jerawat
Authors: Muharram Luthfia Hastiani , Syaputri Fauzia Ningrum , Pertiwi Wulan , Saputri Rizki Fika
Published: May 2022

Skin diseases, including acne, can be caused by a microbial imbalance (dysbiosis). The specific bacteria involved in acne dysbiosis are Cutibacterium (Propionibacterium) acnes and Staphylococcus epidermidis. Black garlic has better potential to be alternative antibiotic and chemical to curing ance and maintaining skin health, because it has antimicrobial potential and can inhibit the decrease in collagen deposition on the skin. These potentials can be alternative of antibiotics and chemicals to treat acne and maintain healthy skin. This study aimed to determine the antibacterial activity of black garlic extract against bacteria that cause acne dysbiosis. Garlic was aging with 3 variations of time (7, 14, and 21 days) then macerated with 70% alcohol and tested for antimicrobial activity to Cutibacterium acnes and Staphylococcus epidermidis with clindamycin as positive control. Black garlic extract provided inhibitory activity against Staphylococcus epidermidis and Cutibacterium acnes. The best recommendation time for aging garlic to prevent skin dysbiosis causes acne is 7 to 14 days.
Review: Moleculary Imprinted Polymer Solid Phase Extraction (MIP-SPE) untuk Pengujian Glibenklamid dalam Cairan Biologis
Authors: Kulsum Imas Nurul Siti , Suryana Shendi , Soni Dang
Published: May 2022

Glibenklamid merupakan salah satu obat antidiabetes golongan sulfonilurea yang digunakan dalam penanganan diabetes melitus tipe 2 dan penggunaannya yang jangka panjang sehingga untuk mengetahui efektivitas obat tersebut diperlukan monitoring kadar obat dalam sampel biologis. Secara umum analisis glibenklamid dapat menggunakan metode Solid Phase Extraction (SPE). Salah satu kelemahan SPE yaitu kurang selektif sehingga kemungkinan masih terdapat komponen lain selain analit yang ikut terekstraksi dari matriks sampel. Maka digunakan teknik Molecularly Imprinted Polymer (MIP) untuk memperbaiki kekurangan SPE. Tujuan dilakukan review ini untuk mengetahui efisiensi penggunaan MIP sebagai metode pemisahan glibenklamid dari berbagai matriks sampel biologis. Review artikel ini dilakukan dengan menelusuri dan mengkaji jurnal ilmiah nasional maupun internasional tentang MIP-SPE yang diperoleh dari situs google.com, Google Scholar, Science Direct, ResearchGate dan PubMed. Berdasarkan hasil review, rata-rata nilai % recovery MIP-SPE lebih tinggi dibandingkan dengan SPE. Penggunaan MIP sebagai metode pemisahan glibenklamid dari berbagai matriks sampel biologis lebih efisien.
Gambaran Karekteristik Fraktur Radius Dital di RSUD Abdul Wahab Sjahranie Samarinda Tahun 2017-2019
Authors: Ihza Muhammad Abduh Bachrl , Tekwan Gregorius , Mu’ti Abdul
Published: May 2022

Distal Radius Fractures are the most common fractures in the world. 17.5% of fractures are categorized as distal radius fractures. Distal radius fractures can occur in both young age and old age. Distal radius fractures mostly occur in young adult age group due to high-energy trauma, and in senior age group due to low-energy trauma and osteoporosis. This research aims to capture the overview of distal radius fracture characteristics at RSUD (Rumah Sakit Umum Daerah – Regional Public Hospital) Abdul Wahab Sjahranie Samarinda. The data in this research are secondary data, gathered from medical records of patients. This research was performed in February 2021. This research is a Descriptive Retrospective study. 146 patients diagnosed with distal radius fractures from January 2017 – December 2019 were selected as samples, using Total Sampling method. The result showed that most cases of distal radius fractures occurred in 10-19 years age group (29 patients, 19.9%), male (87 patients, 59.6%), students (47 patients, 34.2%). Furthermore, the most common type of fractures found was closed fracture type (137 patients, 93.8%), the most common clinical fracture found was unidentified fracture (65 patients, 44.5%), and the most common cause of fractures was from trauma (90 patients, 61.6%).
Pelaksanaan Nasional Health Insurance Pada Aspek Kepesertaan Untuk Mencapai Universal Health Coverage
Authors: Putri Syifa Shidqi , Suryati Chriswardani , Nandini Nurhasmidar
Published: May 2022

National Health Insurance in a country is a program to achieve Universal Health Coverage which ensures that every citizen in the population has access to health services. The existence of mandatory NHI membership rules makes participation a very important aspect. In the development of the implementation of NHI, there was a phenomenon of decreasing participation which became the reason for researchers to research to analyze factors related to NHI participation, obstacles, and efforts made to maintain and increase participation. This research is a type of Literature Review research with a simple data analysis method (simplified approach). There are 12 national articles and 8 international articles that have been selected by researchers as research material. The results showed that the factors related to NHI participation were divided into 3 main factors, namely predisposing factors, enabling factors, and needs factors. The predisposing factors include age, gender, education, occupation, and the number of family members. Enabling factors include knowledge, income/income, and family support. Meanwhile, the need factor contains perception and motivation factors. In addition to finding factors, this study also found obstacles that affect participation in NHI, and efforts that can improve aspects of NHI participation.
Isolated but not alone: the response to the pandemic in the story of PAGs from the Italian case history to the Global Health Summit "Rome Declaration"
Authors:   Active Citizenship Network, c/o Cittadinazattiva APS, Via Cereate 6, 00183 Rome, Italy, Votta Mariano , Cardillo Maira , Papavero Michaela
Published: May 2022

Struggling with practical problems such as the sudden cancellation of scheduled visits and exams and a sense of abandonment and uncertainty. This is how the "ordinary" patients lived the period of the health emergency in Italy. At the same time, civic and rights protection associations, since the beginning, have been active with a sense of responsibility, creativity, and energy, often revealing themselves to be the only point of reference and the only service available to citizens. This is the double side of the coin, in the implications of the pandemic on chronic and rare patients, which emerged from the XVIII National Report on Chronic Policies of Cittadinanzattiva, presented on October 13th, 2020, and entitled: "Isolated but not alone: the response to the pandemic in the story of Patients Advocacy Groups (PAGs)". The Report arised from the story of 34 Italian associations of patients with chronic and rare diseases who adhered to the National Coalition of Associations for Patients suffering Chronic Diseases (CnAMC) of Cittadinanzattiva. This experience thanks to Active Citizenship Network was first socialized on the occasion of the 15th European Patients’ Rights Day held on May 5th & 6th, 2021, and then brought to the attention of the leaders of the G20 and other states, gathered together with the heads of international and regional organizations on the occasion of the Global Health Summit held in Rome on May 21, 2021.
Distance Learning: Methods and Factors for Effective Delivery of Educational Experience
Authors: GLUOKSNYTE Odeta
Published: May 2022

The aim of the article is to analyse the distance education also known as distance/open/distributed learning or remote education. It involves acquiring information from methods other than the traditional way of learning or teaching – physically attending the institutions. Modern day distance learning is influenced by advanced technology which enables connection of thousands of learners. Study resources can be delivered instantly through internet in a wide variety of presentation methods. The article will illustrate and consider the methods used in distance learning as well as effectiveness of it if compared with traditional teaching/learning forms.
The Emergence, Reasons and Results of Resistance to Change in Teachers
Authors: AKDENİZ Rahime Kübra , KONAKLI Tugba
Published: May 2022

This research aims to determine why teachers resist change, the ways they show resistance and the consequences of their behaviours and examine the recommendations of teachers and school administrators to prevent resistance and ensure efficiency in change practices. The sampling of the study, determined through the snowball sampling method and the phenomenological design in the qualitative research model, consists of 20 participants, including 10 school principals and 10 teachers in the study group. The data were collected through the interview technique and examined through content analysis. The themes that emerged from the research findings regarding why teachers resist change were personal and organisational perspectives. The personal perspective theme that emphasized the individual-based reasons against change practices included the subthemes: logic, benefit, concerns and living space. According to the results, the reasons for teachers to resist change stemmed from political considerations, school administration, and the school environment under the organisational perspective theme. Within the frame of these themes and subthemes, we defined that the teachers stood up to change in the active forms of resistance by giving voice directly and protesting and in passive forms of resistance by being silent, shying away from happenings both on an individual and group basis. Results show that resistance behaviours against change have consequences at the individual and organisational levels. The results also manifest that resistance to change affects teachers emotionally and professionally, and it influences the relationships between colleagues and the school environment at the organisational level. To eliminate the resistance to change, the participants suggested that the change should be logical, bring benefits to individuals, be clarified from anxiety-provoking elements, and provide a working process that regulates the living space. The participants also made recommendations for policymakers, school administration and the school environment to prevent resistance. The participant views revealed that the most prominent consideration in eliminating resistance to change in schools is closing the gaps in organisational factors beyond changing the personal perspectives toward change.
A large submandibular salivary stone: A case report
Authors: Budhiraja Grace , Kaur Navjot , Dhingra Harsimrat Singh , Bharti Pulkit , Goyal Nischai
Published: May 2022

Sialolithiasis accounts for the most cases of salivary gland obstruction which leads to recurrent painful swelling of the involved gland which often exacerbates while eating. Stones may be encountered in any of the salivary glands but most frequently in the submandibular gland and its duct. This is a case report of a 40-year-old male patient who had a submandibular sialolith. The sialolith was removed with intraoral approach and no post-operative complications were noted. The article also reviews the various available diagnostic modalities and treatment options.
Organic–Inorganic Composites as Photonic Antenna
Authors: Calzaferri Gion
Published: May 2022

A photonic antenna system is an organized multi-component arrangement in which several chromophoric molecular species absorb the incident light and channel the excitation energy to a common acceptor component. Photonic antenna materials, based on dye–zeolite L composites, collect
excitation energy and transport it over large distances. Fine tuning of dye-loaded zeolite L photonic antenna materials in the size range of 30–3000 nm was realized. Stationary and time-resolved luminescence experiments on an ensemble and space and time resolved luminescence measurements
on single crystal antenna materials have been carried out. Coupling of the photonic antenna information to an external device is in progress.
Artificial Ribonucleases
Authors: Häner Robert
Published: May 2022

Chemically modified oligonucleotides serve as tools in fundamental research as diagnostic reagents and pharmaceutical compounds. Various chemical groups can nowadays be linked to oligonucleotides, In particular, synthetic constructs of oligonucleotides and lanthanide complexes can serve
as artificial ribonucleases. In this paper, some applications of modified oligonucleotides originating from our research efforts directed at the development of artificial ribonucleases are summarized.
Radical Reactions as a Tool for Natural Product Synthesis
Authors: Renaud Philippe
Published: May 2022

Four examples of the synthesis of simple natural products and analogues bearing several adjacent stereogenic centers are presented. In all these syntheses, a highly stereocontrolled radical process is used as a key step.
On the Painting Techniques of Ancient Egyptian Funeral Artefacts
Authors: Rinuy Anne
Published: May 2022

The painting techniques of several ancient Egyptian funeral objects were analysed, prior to conservation treatment. To determine a conservation treatment, it is a priority and necessity to identify the binding media (and possible consolidants). The results indicated a very fragile technique,
used throughout centuries, and revealed the finest methods for modifying the hue of the blue pigment.
Etude de la polychromie de la vierge à l'Enfant de Rarogne
Authors: Soares Marie
Published: May 2022

An investigation of the polychromy of the Virgin with Child, dated 1170, from the collection of the Swiss National Museum, was carried out in the laboratory of conservation research at the Swiss National Museum in collaboration with the ETH Zürich.The pigments belonging to
the artisan's palette and the painting techniques were studied. In this article we will publish the first results of this research. The samples of polychromy were documented, examined under the microcope, and analysed by means of electron microprobe and Raman microspectrometer.
Influence of Sunlight during Harvest on the Oxidation and Yellowing of Natural Mastic Resins Used as Varnishes on Artwork
Authors: Dietemann Patrick , Kälin Moritz , Sudano Christian , Knochenmuss Richard , Zenobi Renato
Published: May 2022

The natural resin mastic, composed largely of triterpenes, is used as a varnish on artwork. This study investigates the influence of light on the autoxidation and yellowing of mastic, both during harvest and after application as a film. The nature of photoinitiation reactions is considered,
as is the propagation of oxidative processes in both light and darkness. Oxidation, radical content and yellowing were studied by graphite-assisted laser desorption mass spectrometry, EPR and UV/VIS spectrometry, respectively. Exposure to sunlight during harvesting is found to strongly affect
the resin. The radical content increases dramatically, and oxidation is accelerated. These differences are also observed during artificial aging under a range of conditions. Mastic that is harvested without exposure to sunlight deteriorates less quickly in all respects. This is attributed
to lack of sunlight-generated radicals and/or labile radical precursors, which are very long-lived in the viscous resin or solid film. Remarkably, radicals are found to be nearly as prevalent in dark-aged films as those aged in light. Oxidation in the dark is also nearly as fast as with continuous
light exposure. These results suggest that dark and light aging are not fundamentally different, in contrast to the conventional model.
Modal Logics of Topological Relations
Authors:   Institut für Theoretische Informatik TU Dresden, Lutz Carsten , Wolter Frank
Published: May 2022

The eight topological RCC8(or Egenhofer-Franzosa)- relations between spatial regions play a fundamental role in spatial reasoning, spatial and constraint databases, and geographical information systems. In analogy with Halpern and Shoham’s modal logic of time intervals based on the Allen relations, we introduce a family of modal logics equipped with eight modal operators that are interpreted by the RCC8-relations. The semantics is based on region spaces induced by standard topological spaces, in particular the real plane. We investigate the expressive power and computational complexity of the logics obtained in this way. It turns our that, similar to Halpern and Shoham’s logic, the expressive power is rather natural, but the computational behavior is problematic: topological modal logics are usually undecidable and often not even recursively enumerable. This even holds if we restrict ourselves to classes of finite region spaces or to substructures of region spaces induced by topological spaces. We also analyze modal logics based on the set of RCC5relations, with similar results.
Description Logics with Concrete Domains and Functional Dependencies
Authors: Lutz Carsten , Miličić Maja
Published: May 2022

Description Logics (DLs) with concrete domains are a useful tool in many applications. To further enhance the expressive power of such DLs, it has been proposed to add database-style key constraints. Up to now, however, only uniqueness constraints have been considered in this context, thus neglecting the second fundamental family of key constraints: functional dependencies. In this paper, we consider the basic DL with concrete domains ALC(D), extend it with functional dependencies, and analyze the impact of this extension on the decidability and complexity of reasoning. Though intuitively the expressivity of functional dependencies seems weaker than that of uniqueness constraints, we are able to show that the former have a similarly severe impact on the computational properties: reasoning is undecidable in the general case, and NExpTime-complete in some slightly restricted variants of our logic.
Expressive Non-Monotonic Description Logics Based on Circumscription
Authors: Bonatti Piero , Lutz Carsten ,   Institut für Theoretische Informatik TU Dresden, Wolter Frank ,   Dept. of Computer Science, University of Liverpool
Published: May 2022

Recent applications of description logics (DLs) strongly suggest the integration of non-monotonic features into DLs, with particular attention to defeasible inheritance. However, the existing non-monotonic extensions of DLs are usually based on default logic or autoepistemic logic, and have to be seriously restricted in expressive power to preserve the decidability of reasoning. In particular, such DLs allow the modelling of defeasible inheritance only in a very restricted form, where non-monotonic reasoning is limited to individuals that are explicitly identified by constants in the knowledge base. In this paper, we consider non-monotonic extensions of expressive DLs based on circumscription. We prove that reasoning in such DLs is decidable even without the usual, strong restrictions in expressive power. We pinpoint the exact computational complexity of reasoning as complete for NPNEXP and NEXPNP, depending on whether or not the number of minimized and fixed predicates is assumed to be bounded by a constant. These results assume that only concept names (and no role names) can be minimized and fixed during minimization. On the other hand, we show that fixing role names during minimization makes reasoning undecidable.
A New n-ary Existential Quantifier in Description Logics
Authors:   Institut für Theoretische Informatik TU Dresden, Baader Franz , Lutz Carsten ,   Institut für Theoretische Informatik TU Dresden, Karabaev Eldar ,   Institut für Theoretische Informatik TU Dresden, Theißen Manfred
Published: May 2022

Motivated by a chemical process engineering application, we introduce a new concept constructor in Description Logics (DLs), an n-ary variant of the existential restriction constructor, which generalizes both the usual existential restrictions and so-called qualified number restrictions. We show that the new constructor can be expressed in ALCQ, the extension of the basic DL ALC by qualified number restrictions. However, this representation results in an exponential blow-up. By giving direct algorithms for ALC extended with the new constructor, we can show that the complexity of reasoning in this new DL is actually not harder than the one of reasoning in ALCQ. Moreover, in our chemical process engineering application, a restricted DL that provides only the new constructor together with conjunction, and satisfies an additional restriction on the occurrence of roles names, is sufficient. For this DL, the subsumption problem is polynomial.
Updating Description Logic ABoxes
Authors:   Institut für Theoretische Informatik TU Dresden, Liu Hongkai , Lutz Carsten ,   Institut für Theoretische Informatik TU Dresden, Miličić Maja ,   Institut für Theoretische Informatik TU Dresden, Wolter Frank
Published: May 2022

Aus dem Abstract: Description logic (DL) ABoxes are a tool for describing the state of affairs in an application domain. In this paper, we consider the problem of updating ABoxes when the state changes. We assume that changes are described at an atomic level, i.e., in terms of possibly negated ABox assertions that involve only atomic concepts and roles. We analyze such basic ABox updates in several standard DLs by investigating whether the updated ABox can be expressed in these DLs and, if so, whether it is computable and what is its size.
Knowledge and implementation of the guidelines of the holistic educational approach in the Republic of Slovenia
Authors: KRISTOVIČ Sebastjan , KRISTOVIČ Jasmina , PANGRČIČ Polonca
Published: May 2022

Introduction: The UNESCO Education Sector and the European Commission for decades emphasise the importance and necessity of introducing a holistic approach to education. The school policies emphasise only a cognitive or rationalist approach and the educational process is operating in a reductionist and deterministic manner. From a sustainable point of view, such consequences are various and multifaceted – on a personal and a social level. Methods: The aim of the research was to establish the level of knowledge of Delors Report, Incheon Declaration and holistic approach among educational professionals (N=525) in Slovenia. A causal non-experimental method of research was used to search the causes for use of international guidelines and knowledge of holistic approaches. The connections between knowledge of documents and demographics were determined with chi-square test, the importance of pillars by statements, compliance with international guidelines by self- assessment. Results: The results show low familiarity with Delors Report (27%), Incheon Declaration (10.8%) and holistic approach (58.6%). The reasons given for a better knowledge of the Delors Report are older age, longer years of service, and the position of principal. Familiarity with that report influences the with holistic approach, but not on importance of certain pillar, or implementation of international guidelines. There is an inversely proportional correlation between familiarity with Incheon Declaration and holistic approach. Conclusion: The awareness of documents and holistic educational approaches is perceived only on a formalistic, declarative level. A solution is in the introduction of logopedagogy/holistic approaches based on anthropological attitude (logotherapy/existential analysis) towards understanding man as a physical, mental and spiritual being.
Plan S the Present and Future of Open Access Publishing
Authors: Trajkovski Vladimir
Published: May 2022

Introduction:This editorial is based on a concise introduction to the basics of open access, describing what it is and showing that it is easy, fast, inexpensive, legal, and a beneficial form of academic publishing. The Internet lets us share perfect copies of our workwith a worldwide audience at virtually no cost. Working in “open access”means: digital, online, free of charge, and free of most copyright and licensing restrictions. The purposeof this paper is to provide an overview about Plan S and its significance for open access publishing. Methods: An analysis of relevant literature, sources from the internet and published literature, personal experience and observations of the author. Findings: Formerly, scholars have written peer-reviewed journal articles for impact, not for money, and are free to consent to open access without losing revenue.Open access is beneficialforauthors and readers of research.PlanSis an initiative to drive wider adoption of open access publishing whichwas launched in 2018 by cOAlitionS, an inter-national consortium of organisations who fund or carry out research. The first and main objective was to require that, from 2021, publicly funded research must only be published in journals or on platforms on an open access basis without embargo. Conclusions: There are10 principles of PlanScovering the way in which all stakeholders should work together to-wards an optimal open access future, drive service standards, promote greater transparency around costs and charges, and more fairly assess the merits of research outputs.
Acupuncture Therapy: An Effective Intervention for Acute Low Back Pain
Authors:   Shaanxi University of Traditional Chinese Medicine, Xianyang, China, Z Sun , Y Bi ,   Shaanxi Hospital of Traditional Chinese Medicine, Xi’an, China, C Ji ,   Shaanxi Hospital of Traditional Chinese Medicine, Xi’an, China
Published: May 2022

Acute low back pain is a relatively common case in the emergency department, and the currently used therapeutic measures can hardly meet the need for immediate relief of patients’ low back pain and functional impairment. This study examines the scientific validity and feasibility of acupuncture intervention in the emergency department for this condition and attempts to provide new treatment ideas that can enrich the treatment of acute low back pain. The text demonstrates the scientificity of acupuncture intervention in acute low back pain from three aspects, including the effectiveness of acupuncture therapy in treating the disease and clinical experimental studies and basic research; it also shows the specific acupuncture points and operation steps required for acupuncture therapy in the form of diagrams, which makes acupuncture therapy operable in clinical use. The use of acupuncture therapy should be attempted in future emergency clinical practice with the aim of promoting its use in the treatment of acute conditions.
Nasal Breath Input: Exploring Nasal Breath Input Method for Hands-Free Input by Using a Glasses Type Device with Piezoelectric Elements
Authors: Ogawa Ryoma , Futami Kyosuke , Murao Kazuya
Published: May 2022

Research on hands-free input methods has been actively conducted. However, most of the previous methods are difficult to use at any time in daily life due to using speech sounds or body movements. In this study, to realize a hands-free input method based on nasal breath using wearable devices, we propose a method for recognizing nasal breath gestures, using piezoelectric elements placed on the nosepiece of a glasses-type device. In the proposed method, nasal vibrations generated by nasal breath are acquired as sound data from the devices. Next, the breath pattern is recognized based on the factors of breath count, time interval, and intensity. We implemented a prototype system. The evaluation results for 10 subjects showed that the proposed method can recognize eight types of nasal breath gestures at 0.82\% of F-value. The evaluation results also showed that the recognition accuracy is increased to more than 90\% by limiting gestures to those with a different breath count or different breath interval. Our study provides the first glasses type wearable sensing technology that uses nasal breathing for hands-free input.
Optimization and noise analysis of the quantum algorithm for solving one-dimensional Poisson equation
Authors: Cui Guolong , Wang Zhimin , Wang Shengbin , Shi Shangshang , Shang Ruimin , Li Wendong , Wei Zhiqiang , Gu Yongjian
Published: May 2022

Solving differential equations is one of the most promising applications of quantum computing. Recently we proposed an efficient quantum algorithm for solving one-dimensional Poisson equation avoiding the need to perform quantum arithmetic or Hamiltonian simulation. In this paper, we further develop this algorithm to make it closer to the real application on the noisy intermediate-scale quantum (NISQ) devices. To this end, we first optimize the quantum 1D-Poisson solver by developing a new way of performing the sine transformation. The circuit depth for implementing the sine transform is reduced from n2 to n without increasing the total qubit cost of the whole circuit, which is achieved by neatly reusing the additional ancillary quits. Then, we analyse the effect of common noise existing in the real quantum devices on our algorithm using the IBM Qiskit toolkit. We find that the phase damping noise has little effect on our algorithm, while the bit flip noise has the greatest impact. In addition, threshold errors of the quantum gates are obtained to make the fidelity of the circuit output being greater than 90%. The results of noise analysis will provide a good guidance for the subsequent work of error mitigation and error correction for our algorithm. The noise-analysis method developed in this work can be used for other algorithms to be executed on the NISQ devices.
A tight lower bound for non-coherent index erasure
Authors: Lindzey Nathan , Rosmanis Ansis
Published: May 2022

The index erasure problem is a quantum state generation problem that asks a quantum computer to prepare a uniform superposition over the image of an injective function given by an oracle. We prove a tight $\Omega(\sqrt{n})$ lower bound on the quantum query complexity of the non-coherent case of the problem, where, in addition to preparing the required superposition, the algorithm is allowed to leave the ancillary memory in an arbitrary function-dependent state. This resolves an open question of Ambainis et al., who gave a tight bound for the coherent case, the case where the ancillary memory must return to its initial state. To prove our main result, we first extend the automorphism principle}of Hoyer et al. to the general adversary method of Lee et al. for state generation problems, which allows one to exploit the symmetries of these problems to lower bound their quantum query complexity. Using this method, we establish a strong connection between the quantum query complexity of non-coherent symmetric state generation problems and the Krein parameters of an association scheme defined on injective functions. In particular, we use the spherical harmonics a finite symmetric Gelfand pair associated with the space of injective functions to obtain asymptotic bounds on certain Krein parameters, from which the main result follows.
Mechanistic Understanding and Metal Tuning as a Strategy for Improving Alkyl–Alkyl Cross-Coupling Catalysis with Early Transition Metals
Authors: Belli Roman , Tafuri Victoria , Roberts Courtney
Published: May 2022

Alkyl–alkyl cross-coupling is a powerful C–C bond forming transformation typically catalyzed by late transition metals. Herein we report a mechanistic investigation into an early transition metal-catalyzed variant of this reaction. Through this mechanistic understanding, an ideal Y catalyst was determined through tuning of the metal in order to optimize for oxidation potential, the rate limiting step in this reaction. A wide substrate scope is revealed that includes a variety of functional groups as well as unactivated substrates.
Exploring the NCS-382 Scaffold for CaMKIIα Modulation: Synthesis, Pharmacology, and Biophysical Characterization of Ph-HTBA as a Novel High-Affinity Brain-Penetrant Stabilizer of the CaMKIIα Hub Domain
Authors: Tian Yongsong , Shehata Mohamed , Gauger Stine , Veronesi Carolina , Hamborg Louise , Thiesen Louise , Bruus-Jensen Jesper , Royssen Johanne Schlieper , Leurs Ulrike , Larsen Anne Sofie , Krall Jacob , Solbak Sara , Wellendorph Petrine , Frølund Bente
Published: May 2022

Ca2+/calmodulin-dependent protein kinase II alpha (CaMKIIα) is a brain-relevant kinase and an emerging drug target for ischemic stroke and neurodegenerative disorders. Despite various reported CaMKIIα inhibitors, their usefulness is limited by low subtype selectivity and brain permeability. (E)-2-(5-Hydroxy-5,7,8,9-tetrahydro-6H-benzo[7]annulen-6-ylidene)acetic acid (NCS-382) is structurally related to the proposed neuromodulator, γ-hydroxybutyric acid, and is a brain-penetrating high nanomolar-affinity ligand selective for the CaMKIIα hub domain. Herein, guided by in silico approaches, we synthesized the first series of NCS-382 analogs displaying improved affinity and preserved brain permeability. Specifically, we present Ph-HTBA (1i) with enhanced mid-nanomolar affinity for the CaMKIIα binding site and a marked hub thermal stabilization effect along with a distinct CaMKIIα Trp403 flip upon binding. Moreover, Ph-HTBA has good cellular permeability and low microsomal clearance and shows brain permeability after systemic administration to mice, signified by a high Kp,uu value (0.85). Altogether, our study highlights Ph-HTBA as a promising candidate for CaMKIIα-associated pharmacological interventions and future clinical development.
Camphene-Assisted Fabrication of Free-Standing Lithium-Ion Battery Electrode Composites
Authors: Weeks Jason , Lauro Samantha , Burrow James , Xiao Han , Pender Joshua , Ellison Chris , Mullins Charles
Published: May 2022

Continually increasing technological demands and widespread adoption of electric vehicles has spurred significant motivation to improve the performance of lithium-ion batteries (LIBs). In addition to improving intrinsic battery chemistry, optimizing electrode morphology and cell design can unlock increased energy density and rate capability to enable the adoption of next generation LIBs for societal decarbonization. Although free-standing electrode (FSE) architectures hold the potential to dramatically increase the gravimetric and volumetric energy density of LIBs by eliminating the parasitic dead weight and volume associated with traditional metal foil current collectors, current FSE fabrication methods suffer from insufficient mechanical stability, electrochemical performance, or industrial adaptability. Here, we demonstrate a scalable camphene-assisted fabrication method that allows simultaneous casting and templating of FSEs comprised of common LIB materials with performance superior to foil-cast counterparts. These porous, lightweight, and robust electrodes simultaneously enable enhanced rate performance by improving mass and ion transport within the percolating conductive carbon pore network and eliminating current collectors for efficient and stable Li+ storage (> 1000 cycle in half-cells) at increased gravimetric and areal energy densities. Compared to conventional foil-cast counterparts, the camphene-derived electrodes exhibit ~1.5x enhanced gravimetric energy density, increased rate capability, and improved capacity retention in coin-cell configurations. A full cell with freestanding anode and cathode cycled for over 250 cycles with greater than 80% capacity retention at an areal capacity of 0.73 mAh/cm2 . This active-material-agnostic electrode fabrication method holds the potential to tailor the morphology of flexible, current-collector-free electrodes to optimize LIBs for high power or high energy density Li+ storage and is applicable to other electrochemical technologies and advanced manufacturing methods
Predicting Indium Phosphide Quantum Dot Properties from Synthetic Procedures Using Machine Learning
Authors: Nguyen Hao , Dou Florence , Park Nayon , Wu Shenwei , Sarsito Harrison , Diakubama Benedicte , Larson Helen , Nishiwaki Emily , Homer Micaela , Cash Melanie , Cossairt Brandi
Published: May 2022

Predictions of chemical reaction outcomes using machine learning (ML) has emerged as a powerful tool for advancing materials synthesis. However, this approach requires large and diverse datasets, which are extremely limited in the field of nanomaterials synthesis due to inconsistent and non-standardized reporting in the literature and a lack of understanding of synthetic mechanisms. In this study, we extracted parameters of InP quantum dot (QD) syntheses as our inputs, and resultant properties (absorption, emission, diameter) as our outputs from 72 publications. We “filled in” missing outputs using a data imputation method to prepare a complete dataset containing 216 entries for training and testing predictive ML models. We defined the descriptor space in two ways (condensed and extended) based on either chemical identity or the role of reagents to explore the best approach for categorizing input features. We achieved mean absolute errors (MAEs) as low as 20.29, 11.46, and 0.33 nm for absorption, emission, and diameter respectively with our best ML model across diverse synthetic methods. We used these models to deploy an accessible and interactive webapp for designing syntheses of InP (https://share.streamlit.io/cossairt-lab/indium-phosphide/Hot_injection/hot_injection_prediction.py). Using this webapp, we investigated the power of ML to uncover chemical trends in InP syntheses, such as the effects of common additives, like zinc salts and trioctylphosphine. We also designed and conducted new experiments based on extensions of literature procedures and compared our experimentally measured properties to predictions, thus evaluating the “real-life” accuracy of our models. Conversely, we used inverse-design to obtain InP QDs with specific properties. Finally, we applied the same approach to train, test, and launch predictive models for CdSe QDs by expanding a previously published dataset. Altogether, our data pre-processing method and ML implementations demonstrate the ability to design materials with targeted properties and explore underlying reaction mechanisms even when faced with limited data resources.