bluuebunny/crossref_metadata_2025 huggingface dataset:
THE ROLE OF PATIENTS AND MEDICAL SPECIALISTS IN ACHIEVING HIGHER LEVEL OF THERAPY COMPLIANCE- AN EXAMPLE WITH WILLINGNESS TO PARTICIPATE IN CLINICAL TRIALS
Authors: Stoev Svetoslav , Atanasov Vladimir , Getov Ilko
Published: October 2016

BACKGROUND: Patients’ compliance is a leading factor in achieving determined endpoints of a treatment process. Low patient compliance with prescribed therapeutic plan is very common in both ambulatory practice and clinical trials. Non-adherence of subjects in clinical studies can seriously jeopardize validity of results obtained during randomized clinical trials (RCTs).METHODS: Both systematic literature review and cross-sectional survey were conducted among physicians and patients to determine evaluation of therapy adherence by both groups. RESULTS: According to the analytical reviews in published articles, the most common definition of therapy adherence or compliance is “the ability and willingness of patients to abide to a prescribed therapeutic regimen”. There is a strong correlation between patient adherence to the therapeutic regimen determined by the study protocol of RCTs, and the validity of efficacy and safety evaluation of the investigated medicinal product. Analysis of the results from the conducted survey lead to the conclusion that 35% of physician’s state that the results of ongoing therapy are highly dependent on patient compliance. As far as patients are concerned, almost half of the respondents have answered they comply with the prescribed therapy and would evaluate the treatment process as successful. Both patients and medical professionals declare their willingness to participate in clinical trials and strictly stick to the requirements of the study protocol.Conclusion: These results decisively confirmed that the control of a disease is a bilateral process between the patient and the doctor. Patient satisfaction with their current therapy directly correlates with the results of treatment. Majority of patients evaluate their possible participation in a clinical trial as an opportunity to get an access to a better medical service. Both medical professionals and patients declare their strong motivation to comply with the therapeutic plan if it is a part of a clinical study protocol.
INTERACTION BETWEEN BIG DATA AND COMPETITION LAW IN DIGITAL SINGLE MARKET
Authors: Puksas Andrius
Published: October 2016

Representatives of undertakings are familiar with the importance of carefully handling and protecting personal data. However, this does not lessen the importance of improving legislation regarding data management. Both the content and quantity of information have value and potentially determine the strength of the undertakings that can access such information. This influences the constant growth in demand to improve the legal framework. The consumers and institutions responsible for consumer protection are the main initiators and stakeholders of such demand. The constant growth in the amount of preserved data more sharply raises the questions about data protection. The potential risk raises proposals enabling a competition law in data protection. The article examines such possibility in the light of digital single market. This possibility is analyzed in the light of interaction between the data protection and competition law and covers trends on enabling competition law in data protection. To ensure proper data protection, cooperation among institutions should be encouraged.
EXPLORATION OF STYLIZED FACTS IN THE ARTIFICIAL LIFE SYSTEM AVIDA
Authors: Koyano Shinta , Pichl Lukáš
Published: October 2016

Population dynamics in the evolution, extinction, and re-evolution of various logic-function performing organisms is studied in the artificial life system, Avida. Following the work of Yedid (2009), we design an experiment involving two extinction regimes, pulse-extinction (corresponding to a random-kill event) and press-extinction (corresponding to a prolonged episode of rare resources). In addition, we study the effect of environmental topology (toroidal grid and clique graph). In the study of population dynamics, logarithmic returns are generally applied. The resulting distributions display a fat tail form of the power law: the more complex the logic function (in terms of NAND components), the broader the full width at half a maximum of the histogram. The power law exponents were in sound agreement with those of “real-life” populations and distributions. The distributions of evolutionary times, as well as post-extinction recovery periods, were very broad, and presumably had no standard deviations. Using 100 runs of 200,000 updates for each of the four cases (about 1 month of central processing unit time), we established the dynamics of the average population, with the effect of world topology.
MOBILE 5G TECHNOLOGY ADOPTION INVESTMENT TIMING DECISION MAKERS CLUSTERING AND WILLINGNESS TO INVEST UNDER VOLATILE DEMAND CHANGES
Authors: Adamauskas Saulius , Krušinskas Rytis
Published: October 2016

Enterprises need to identify the optimal timing for technological change in order to increase competitiveness and increase the value of the company in an uncertain demanding environment. Investment decisions for adopting new technologies are costly and sometimes risky because technological investments are irreversible. To simulate the process, comprehensive technological adoption regarding investment timing was used in a management decision support model. The constructed model is structured as follows: 1) historical demand paths analysis; 2) application of statistical data validity tests; 3) the forecast of market parameters regarding data arrays using the geometric Brownian motion method, based on Monte Carlo simulation; 4) determination of technological life cycle using a Hodrick–Prescott filter; 5) technological adoption time-window determination; and 6) calculation of company net present values (NPV) based on change in free cash-flow. The model for mature 5G mobile markets, created and empirical tested, was performed in relation to 18 largest Europe mobile service providers, as potential decision makers operating across 33 countries. Results confirmed that selection of the technological investment time depends on companies’ strategic financial decisions and financial state. The performed simulations revealed the consequence of 5G technology investment for investor roles, clustered according to financial data within a 5-year period (2010–2014). The analyzed companies were assigned to roles of pioneers-innovators, pragmatics, followers, or laggards. Finally, it is assumed and argued that financial parameters indicate the willingness to adopt new technologies in a global technologically changing environment.
PARAMETRIC DESIGN OF DELTA ROBOT
Authors: Gürgen Mert , Eryılmaz Cenk , Ömürlü Vasfi Emre
Published: October 2016

This article describes a sophisticated determination and presentation of a workspace volume for a delta robot, with consideration of its kinematic behavior. With the help of theoretical equations, optimization is performed with the aid of the stiffness and dexterity analysis. Theoretical substructure is coded in Matlab and three-dimensional (3D) data for delta robot are developed in computer-aided design (CAD) environment. In later stages of the project, both 3D and theoretical data are linked together and thus, with the changing design parameter of the robot itself, the Solidworks CAD output adapts and regenerates output with a new set of parameters. To achieve an optimum workspace volume with predefined parameters, a different set of robot parameters are iterated through design optimization in Matlab, and the delta robot design is finalized and illustrated in the 3D CAD environment, Solidworks. This study provides a technical solution to accomplish a generic delta robot with optimized workspace volume.
LATHE SELECTION USING ANALYTIC HIERARCHY PROCESS AND INFORMATION AXIOM
Authors: Kentli Aykut , Akbaş Serhat
Published: October 2016

Selection of appropriate equipment, place, or employee is a problem that needs consideration by industry, as capacities develop and efficiencies become more valued over the recent decades. Several decision-making techniques have been developed and applied to many different areas to evaluate their reliability. This study focuses on the application of a hybrid decision-making technique of Analytic Hierarchy Process and Information Axiom to solve the problem of lathe selection. Results show that appropriate machine tools can easily be selected within a short time using this approach.
MICROSCOPIC MODEL OF KNOWLEDGE INCREASE AND ITS VERIFICATION
Authors: Dudáková Simona , Benko Michal , Lacsný Boris , Teleki Aba
Published: October 2016

Knowledge growth models, based on primary principles, play a fundamental role in the cognitive sciences. The authors submit an extension of their model (ENKI) from 2005, with the results of the practical testing, which was performed using the method developed for the purpose of model ENKI of solving tasks with immediate feedback. This was applied to the curriculum of parallel configuration of resistors in electrical circuits. There were 73 pupils from six elementary schools in attendance for testing. Analysis based on ENKI indicates that three autonomous units (scopes) were evaluated simultaneously during the assessment. Results showed that 25% of pupils knew the curriculum, 9% of pupils showed no improvement, while 66% of pupils showed an increased success in accordance with the ENKI model (significance level ). Solving 7.2 typical tasks on average, by a method of immediate feedback resulted in 90% of the pupils mastering the curriculum.
Short Communication: Screening the potency of Zingiberaceae leaves as antioxidant and antiaging agent
Authors: ZAHRA UMMI , KARTIKA YUNI , BATUBARA IRMANIDA , DARUSMAN LATIFAH K , MADDU AKHIRUDDIN
Published: October 2016

Abstract. Zahra U, Kartika Y, Batubara I, Darusman LK, Maddu A. 2016. Short Communication: Screening the potency of Zingiberaceae leaves as antioxidant and antiaging agent. Nusantara Bioscience 8: 221-225. Zingiberaceae is a family of plant with antioxidant, anticancer, and antiaging activities. The use of the leaves part of this family has never been explored. Therefore, the aim of this research is to evaluate the antioxidant and antiaging activities of some Zingiberaceae’s leaves. The species of Zingiberaceae used in this study are Alpinia galanga (L), Curcuma aeruginosa Roxb, Curcuma longa L, Curcuma zedoaria, Curcuma xanthorrhiza Roxb, Boesenbergia rotunda (L.), Elettaria cardamomum, Zingiber zerumbet, Zingiber officinale Roscoe, and Zingiber purpureum Roscoe. Leaves were extracted with 2 different solvents sequentially: ethyl acetate and methanol. Total phenolic and flavonoid contents of the extracts were determined spectrophotometrically. Antioxidant activities were tested by using DPPH (2,2-diphenyl-1-picrylhydrazyl ) and ABTS (2,2'-azino-bis-3-ethyl benzothiazoline-6-sulfonic acid), whilst antiaging activity was tested by using antiglycation method. The results showed that the flavonoid content of the extracts was in the range of 0.83-25.17 g QE/100 g extract with total phenolic content ranging from 9.80-91.71 GAE mg/100 mg extract. The methanol extract of Curcuma xanthorrhiza displayed the highest antioxidant capacity in the DDPH (IC50 282.35 mg/mL) and TEAC (10.08%) assays, followed by the ethyl acetate extract of C. longa, ethyl acetic extract of C. xanthorrhiza and methanol extract of Z. officinale, while the most active antiglycation is the methanol extract of Z. officinale (IC50 203.85 mg/L).
Os 20 anos da comunidade dos países de língua portuguesa na imprensa brasileira: discutindo as condições para uma communitas possível
Authors: Góes José Christian , Antunes Elton
Published: October 2016

O presente estudo analisa as informações que a imprensa brasileira vem divulgando acerca da Comunidade dos Países de Língua Portuguesa (CPLP), que completa 20 anos em 2016. Segundo as ideias de communitas trabalhadas por Roberto Esposito (2012), o que une os membros de uma comunidade é uma falta, uma carência, gerando uma obrigação, um dever recíproco e fraterno. Nessas condições, a CPLP pode ser imaginada como uma communitas possível? No caso do Brasil, o desafio começa pelo enfrentamento da invisibilização da comunidade. Nossa investigação revelou que, desde o início, a CPLP esteve ausente nos dois maiores jornais brasileiros: Folha de S. Paulo e O Globo. Até os poucos registros encontrados são exemplares para debater esse não reconhecimento. Todavia, as construções identitárias entre os povos da CPLP, as condições históricas comuns e a conjuntura contemporânea são potencialidades que provocam uma discussão sobre essa comunidade na perspectiva da communitas.
O império contra-ataca: a produção secreta de propaganda feita por estrangeiros para projecção internacional de “portugal do ultramar”
Authors: Piçarra Maria do Carmo
Published: October 2016

Quando se iniciou a contestação internacional à posse de colónias por Portugal, como é que o Estado Novo usou o cinema na projecção de uma retórica luso-tropical? A partir de 1965, vários documentários realizados pelos franceses Jean-Noel Pascal-Angot e Jean Leduc foram exibidos internacionalmente, no circuito comercial de distribuição cinematográfica, em festivais, nas televisões e mostrados às principais organizações não governamentais. O financiamento desta produção supostamente independente - em que o Brasil era apontado como o modelo social em recriação em Angola enquanto que o funcionamento da Commonwealth era assumidamente inspirador em Moçambique -, dando enfoque ao desenvolvimento económico e social, foi mantido confidencial. “Do Minho a Timor somos todos portugueses” era a “evidência” que este cinema encomendado queria impor. Através da análise de filmes de propaganda do colonialismo português realizados por realizadores franceses questiono, porém, se a afirmação do “orgulhosamente sós” foi uma declinação retórica, para afirmação da política colonial internamente, enquanto para o exterior se projectava, progressivamente e com maior intensidade durante o Marcelismo mas ainda durante o Salazarismo, a imagem de outro Portugal, menos espartilhado, em termos de costumes, e aberto ao capital estrangeiro.
Tarzán y el Dr. Moreau contra los subhumanos y los Zombis Vudú: discursos colonialista y anticolonialista en el hollywood pre-code (1932-1934)
Authors: Aragón Alfonso M. Rodríguez de Austria Giménez de
Published: October 2016

El presente artículo analiza los discursos colonialista y anticolonialista implícitos en seis películas de Hollywood de los primeros años treinta, antes de que se impusiera definitivamente el discurso hegemónico sustentado por el código de censura de 1934. El recorrido comienza con Tarzán, guardián de las colonias africanas, y termina con Island of Lost Souls, una película que los aborígenes australianos tenían prohibido ver.
Los macheteros y el rol de la prensa en la lucha de liberación nacional en Puerto Rico
Authors: Pesante Francisco
Published: October 2016

El siguiente artículo recapitula parte la cobertura de prensa de la detención, el encarcelamiento y el procesamiento de los miembros de la organización separatista clandestina puertorriqueña Los Macheteros. Con la intensión de acentuar la importancia de la prensa independiente y los organismos de solidaridad política para romper el cerco informático por parte de las autoridades o sectores de la prensa comercial (mass media) que reproducen los discursos hegemónicos del estado. Además de reconocer su valor como fuente histórica. También se reseña algunos acontecimientos en los que las autoridades coloniales interfirieron con el derecho a la libertad de prensa, al interferir con algunos periodistas que trabajaron de cerca las historias relacionadas a Los Macheteros. Eventos que permiten reflexionar sobre la reproducción o desafíos de las posturas oficiales articuladas por las autoridades contra los miembros de la organización clandestina y la cobertura de los acontecimientos por la prensa.
Visualization approaches to support healthy aging: A systematic review
Authors: Backonja Uba , Chi Nai-Ching , Choi Yong , Hall Amanda K , Le Thai , Kang Youjeong , Demiris George
Published: October 2016

Background: Health technologies have the potential to support the growing number of older adults who are aging in place. Many tools include visualizations (data visualizations, visualizations of physical representations). However, the role of visualizations in supporting aging in place remains largely unexplored.Objective: To synthesize and identify gaps in the literature evaluating visualizations (data visualizations and visualizations of physical representations), for informatics tools to support healthy aging.Methods: We conducted a search in CINAHL, Embase, Engineering Village, PsycINFO, PubMed, and Web of Science using a priori defined terms for publications in English describing community-based studies evaluating visualizations used by adults aged ≥65 years.Results: Six out of the identified 251 publications were eligible. Most studies were user studies and varied methodological quality. Three visualizations of virtual representations supported performing at-home exercises. Participants found visual representations either (a) helpful, motivational, and supported their understanding of their health behaviors or (b) not an improvement over alternatives. Three data visualizations supported understanding of one’s health. Participants were able to interpret data visualizations that used precise data and encodings that were more concrete better than those that did not provide precision or were abstract. Participants found data visualizations helpful in understanding their overall health and granular data.Conclusions: Studies we identified used visualizations to promote engagement in exercises or understandings of one’s health. Future research could overcome methodological limitations of studies we identified to develop visualizations that older adults could use with ease and accuracy to support their health behaviors and decision-making.
NOTAS CIENTÍFICAS: ANIDAMIENTO DE PALOMA TORCAZA (Zenaida auriculata) EN RASTROJOS DE SORGO
Authors: Dardanelli Sebastián , Orduna Laura Addy , Canavelli Sonia
Published: October 2016

La paloma torcaza (Zenaida auriculata) es una de las especies de aves más co-munes y abundantes de Argentina, con gran capacidad de adaptación a los am-bientes modificados por el hombre. Un aspecto clave del éxito de esta especiees su capacidad para anidar de manera colonial en remanentes de bosque enpaisajes agrícolas. Este factor ha contribuido significativamente al crecimientopoblacional experimentado por la especie en las últimas décadas. Se presentael hallazgo de una nidada colonial en rastrojos de sorgo. En octubre de 2013 selocalizó una colonia de anidamiento de paloma torcaza en un lote con rastrojosde sorgo. En dicho lote, se realizaron 5 transectas de faja. Se obtuvo un promediode 0,89 nidos (±0,19) por m 2 y 1,79 (±0,17), huevos por nido. La mayoría (93,4 %)de los huevos estaba sano y el resto (6,6 %) mostraba signos de depredación.Éste sería el primer registro publicado de anidamiento colonial de torcaza enrastrojos de cultivo de sorgo. Establecer la frecuencia de este comportamientode anidamiento a escala regional y estimar el impacto que podría tener sobre elcrecimiento poblacional de esta especie sería importante para comprender, demanera más cabal, los aumentos poblacionales experimentados por esta palomaen los últimos años.
The Effect of Water-Soluble Stem Extract “Kayu Kuning“ (Arcangelisia flava L.Merr) On The Growth Inhibition of Candida albicans ATCC 10231 and Trichophyton mentagrophytes IN VITRO
Authors: Setyowati Rini , Sudarsono Sudarsono , P Setyowati E
Published: October 2016

“Kayu kuning” (Arcangelisia flava L.Merr) was used when someone has a skin problem caused by Candida albicans and Trichophyton mentagrophytes. Scientific based medicine on this traditional knowledge was necessary be  done. Stem powderwas extracted by  distilled water.The extract was then evaporated. Qualitative and quantitative analysis of the active substance e.g., Berberin chloride by Thin Layer Chromatography (TLC)  The antifungal activity againts Candida albicans and Trichophyton mentagrophyteswere tested by using agar diffusion and microdilution methods.  The absorbance from microdilution were analized by One way ANOVA. The conclusion showed that the extract contained 1.55±0.12% w/walkaloid calculated as Berberine chloride. The inhibition zone for Candida albicans and Trichophyton mentagrophytes were 16.65±4.52 and 6.55±0.05 mm respectively. The MIC vallue for both fungi was 10 mg/mL.The MBC value for Candida albicans was 40 mg/mL and for Trichophyton mentagrophytes was 50 mg/mL. From the analysis with one-way ANOVA, shows that there are significant differences between the positive control group and the test solution with the negative control group with p=0.020 for Candida albicans and p=0.028 for Trichophyton mentagrophytes (p<0.050). Post hoc Tukey analysis results showed  that both inter-group and between the concentration of the test solution to the control group did not differ significantly positive because the value of p>0.050.
Larvicidal Activity of A Mixture of Cashew Nut Shell Liquid and Water-Soluble Extract of Soap Nut Fruit (Sapindus rarak DC.) Against 3rd Instar Larvae of Aedes aegypti
Authors: Raraswati Glory Resia , Sudarsono Sudarsono , Mulyaningsih Budi
Published: October 2016

Cashew Nut Shell Liquid (CNSL) which has been known as a waste of processing cashew fruits which is contain phenolic compounds have activity as larvicides. Cashew nut shell liquid is not soluble in the water where the larvae grow. Cashew nut shell liquid mixed with water-soluble extract of soapnut fruit which serves as a natural surfactant that can emulsify oil in water. The test subjects were larvae of Aedes aegypti third instar. Test subjects were divided into treatment group and control group. In the treatment group, test subjects were  the mixture of CNSL and Ethylacetat Soluble Extract (ESE) in tap water. The Larvae mortality observations were done 24 hours after the treatment. LC50 and LC90 as final test data were analyzed using probit analysis. Extract constituents   of CNSL and Water Soluble Extract of SoapNut fruit (WSEoSN) were  investigated using Thin Layer Chromatography (TLC) method. The effect of CNSL as larvicides against third instar larvae of Ae. aegypti with were LC50 of 14,12 ppm, while the LC90 of 24,85 ppm.
The Antidepressant Effects of (Arcangelisia flava (l.) Merr) Water-Soluble Extract in Balb-C Mice Reviewed from Immobility Time by Forced
Authors: A Tiara , H Arief R , Sudarsono Sudarsono
Published: October 2016

This study was conducted to examine / determine the antidepressant effects of (Arcangelisiaflava L.) on immobility time of the white male mice strain Balb-c by the forced swim test method. The method of research using laboratory animals such as 25 micewas divided into 5 groups. As a negative control group was only given distilled water ad libitum. Amitryptiline was used as the positive control group; the experiment group was a water-soluble extract of A.flava by  multiple doses. The results showed that the best antidepressant effects were312 mg/kgBW ; it had a minimum of immobility time compared with the other groups.
Open Conversion after Aortic Endograft Infection Caused by Colistin-Resistant, Carbapenemase-Producing Klebsiella pneumoniae
Authors: Montelione Nunzio , Menna Danilo , Sirignano Pasqualino , Capoccia Laura , Mansour Wassim , Speziale Francesco
Published: October 2016

A 62-year-old man presented with fever, abdominal pain, and malaise 13 months after emergency endovascular aortic repair. Computed tomographic angiograms showed a periprosthetic fluid and gas collection, so infection was diagnosed. Open conversion was performed, involving endograft explantation and in situ aortic reconstruction. Cultures and the explanted prosthesis were positive for carbapenemase-producing Klebsiella pneumoniae, resistant to colistin. Because of the sparse data on endograft infections caused by this pathogen, we placed the patient on an empiric double-carbapenem regimen for 4 weeks. Symptomatic recovery occurred after 21 days. On the 30th day, we deployed a stent to treat a new pseudoaneurysm. Three years later, the patient had no signs of persistent or recurrent infection. We think that this is the first report of aortic endograft infection caused by colistin-resistant, carbapenemase-producing K. pneumoniae.
Ewing Sarcoma in the Right Ventricle
Authors: Petrovic Marija , Zhao Bihong , Thangam Manoj , Loyalka Pranav , Buja L. Maximilian , Kar Biswajit , Gregoric Igor D.
Published: October 2016

Ewing sarcoma is the second most prevalent malignant primary bone tumor but constitutes only a small proportion of cardiac metastases. We present a case of asymptomatic Ewing sarcoma metastatic to the right ventricle.

A 36-year-old man presented for evaluation and resection of a pedunculated right ventricular cardiac tumor. Three years before, he had been diagnosed with translocation-negative Ewing sarcoma, for which he had undergone chemotherapy and amputation of the left leg below the knee. We resected the right ventricular tumor. Analysis of the resected mass supported the diagnosis of metastatic Ewing sarcoma. Postoperative transthoracic echocardiograms showed normal biventricular size and function. One year later, the patient had no recurrence of the sarcoma. In addition to discussing this case, we review the relevant medical literature.
Delayed-Onset Left Main Coronary Artery Obstruction More than 24 Hours after Balloon-Expandable Transcatheter Aortic Valve Replacement
Authors: Isawa Tsuyoshi , Tada Norio , Ootomo Tatsushi
Published: October 2016

Coronary obstruction during or after transcatheter aortic valve replacement is a rare and catastrophic sequela that occurs most frequently just after valve implantation. Even rarer is the delayed clinical presentation, in some few patients, of coronary obstruction on the day after self-expandable valve implantation. Here we describe a case of balloon-expandable (not self-expandable) transcatheter aortic valve replacement, followed by partial obstruction of the left main coronary artery on the day after that procedure in a 93-year-old man, despite normal left ventricular contraction just after valve implantation. Visual evaluation of the echocardiogram for left ventricular wall motion was not sufficient, by itself, to achieve early diagnosis of the obstruction.

We performed emergency percutaneous coronary intervention. Ninety days after the procedure, the patient was in New York Heart Association functional class I.
The Effect of Interferon-γ and Lipopolysaccharide on the Growth of Francisella tularensis LVS in Murine Macrophage-like Cell Line J774
Authors: Holická Monika , Novosad Jakub , Loudová Martina , Kudlová Manuela , Krejsek Jan
Published: October 2016

Background:Francisella tularensis, a causative agent of human tularemia, displaying the ability to proliferate inside the human cells. Aims: To evaluate the growth potential ofF. tularensisLVS strain in macrophage-like cell line J774 modulated by recombinant interferon γ andE. coliderived lipopolysaccharide. Results: Stimulation of J774 cells either by interferon-γ or lipopolysaccharide alone, or especially in combination before infectionF. tularensis, revealed protective effects. Higher concentrations of stimulating agents were needed to inhibit ongoingF. tularensisinfection. Conclusions: Stimulation of J774 cell line by combination of interferon-γ with lipopolysaccharide inhibits the intracellular growth ofF. tularensis.
Zehn Jahre Digitalisierung in der SUB Hamburg – zehn Jahre Strategien in Progress
Authors: Hagenah Ulrich , Wendt Kerstin
Published: October 2016

Die SUB Hamburg digitalisiert seit zehn Jahren hamburgisches Kulturerbe. Kernbestände zur Landesgeschichte und Landeskunde, die Sondersammlungen und physisch gefährdeten Bestände stehen dabei im Mittelpunkt. Gemeinsam mit der Universität und anderen Einrichtungen werden weitere kulturell und wissenschaftlich bedeutsame Sammlungen für die digitale Transformation in den Blick genommen. Ihre Workflow- und Präsentationsplattform Kitodo entwickelt die SUB im Konsortium aktiv weiter. Das von der SUB kooperativ betriebene Regionalportal HamburgWissen Digital bündelt die Recherche nach digitalen Ressourcen zur Geschichte und Landeskunde der Metropolregion. Zentrale Zukunftsperspektive ist die passgenaue Bedienung wissenschaftlicher und öffentlicher digitaler Bedarfe.
Fünfzehn Jahre Digitalisierung in der Universitäts- und Stadtbibliothek Köln: Bilanz, Wandlung und Ausblick
Authors: Hoffrath Christiane
Published: October 2016

Dieser Beitrag möchte anhand der im Fokus stehenden Altbestandsdigitalisierung nicht nur den Weg von den ersten Schritten bis hin zu den aktuellen Herausforderungen der Sammlungsdigitalisierung und der digital humanities

Vgl.: Schmale, Wolfgang (Hg.): Digital humanities. Praktiken der Digitalisierung, der Dissemination und der Selbstreflexivität. Stuttgart 2015; Kurz, Susanne: Digital humanities . Grundlagen und Technologien für die Praxis. 2. Aufl. Wiesbaden 2016.

beschreiben, sondern die „Digitalisierung“ an sich in einen größeren Rahmen stellen. Digitalisierung bedeutet im Bibliothekswesen längst nicht mehr nur Scannen anstatt Kopieren, die Einbindung eines Links in eine Titelaufnahme oder die Aggregation freier digitaler Sammlungen für den eigenen Katalog. Digitalisierung umfasst ebenso die Automatisierung im Sinne vernetzter Produktionsprozesse. Ziel ist die Vermeidung redundanter Arbeitsgänge, sei es durch die Nachnutzung bereits vorhandener Daten oder der Infrastruktur im technischen und personellen Bereich für weitere digitale Projekte und Dienstleistungen, ohne dass dies erneut einen nennenswerten (Kosten-) Aufwand implizieren würde. Und schließlich heißt Digitalisierung in Bibliotheken auch das Schritthalten mit technischen Entwicklungen und den Anforderungen unserer Nutzer.
Vitamin K plasma levels determination in human health
Authors: Fusaro Maria , Gallieni Maurizio , Rizzo Maria Antonietta , Stucchi Andrea , Delanaye Pierre , Cavalier Etienne , Moysés Rosa M.A. , Jorgetti Vanda , Iervasi Giorgio , Giannini Sandro , Fabris Fabrizio , Aghi Andrea , Sella Stefania , Galli Francesco , Viola Valentina , Plebani Mario
Published: October 2016

Vitamin K (phylloquinone or vitamin K1and menaquinones or vitamin K2) plays an important role as a cofactor in the synthesis of hepatic blood coagulation proteins, but recently has also aroused an increasing interest for its action in extra-hepatic tissues, in particular in the regulation of bone and vascular metabolism. The accurate measurement of vitamin K status in humans is still a critical issue. Along with indirect assays, such as the undercarboxylated fractions of vitamin K-dependent proteins [prothrombin, osteocalcin (OC), and matrix gla protein], the direct analysis of blood levels of phylloquinone and menaquinones forms might be considered a more informative and direct method for assessing vitamin K status. Different methods for direct quantification of vitamin K serum levels are available. High-performance liquid chromatography (HPLC) methods coupled with post-column reduction procedures and fluorimetric or electrochemical detection are commonly used for food and blood analysis of phylloquinone, but they show some limitations when applied to the analysis of serum menaquinones because of interferences from triglycerides. Recent advancements include liquid chromatography tandem mass spectrometry (LCMS/MS) detection, which assures higher specificity. The optimization and standardization of these methods requires specialized laboratories. The variability of results observed in the available studies suggests the need for further investigations to obtain more accurate analytical results.
High Selectivity Wideband Bandpass Filter Using Stub Loaded Resonator
Authors: Ma Xing-Bing , Jiang Ting
Published: October 2016

This article presents a high selectivity wideband bandpass filter (BPF) adopting stub loaded resonator. Hereinto, aim passband is determined by BPF without stub embedded, which is only composed of four half-wavelength open-loop resonators. Based on typical tapped-line coupling, two same stubs are located at physical middle points of two resonators connected with I/O feed lines, respectively. Due to embedded point at middle of loaded resonator, the stub with two open-end branches has no influence on original half-wavelength resonant frequency, and aim passband keeps unchanged. Because of different even-mode resonant frequencies between loaded and unloaded resonators, no new passband is constructed. With the help of embedded stubs, original transmission zero (TZ) near low-edge of aim passband is shifted towards passband, and a new TZ is introduced near high-edge. High selectivity and good passband characteristics are obtained optimizing sizes of stubs, I/O tapped position and top open-end length of loaded resonator.
On the covering number of small symmetric groups and some sporadic simple groups
Authors: Kappe Luise-Charlotte , Nikolova-Popova Daniela , Swartz Eric
Published: October 2016

A set of proper subgroups is a cover for a group if its union is the whole group. The minimal number of subgroups needed to cover
Experimentally Validated CFD Model for Gas-Liquid Flow in a Round-Bottom Stirred Tank Equipped with Rushton Turbine
Authors: Gradov Dmitry Vladimirovich , Laari Arto , Turunen Ilkka , Koiranen Tuomas
Published: October 2016

Hydrodynamics of gas-liquid flow in a round-bottom stirred tank is modelled at two gas flow rates, constant bubble size and agitator speed of 300 rpm. A round-bottom tank equipped with four baffles and a Rushton turbine was chosen to represent a typical reactor used in hydrometallurgical processes operating under pressure. The applicability of different momentum interchange models and the Realizable k-ε, SST k-ω, and RSM turbulence models was studied using CFD software. The results were compared and validated against experimental data from Particle Image Velocimetry measurements by means of liquid and gas velocity distributions. In addition, energy balance between power input and dissipation energy was compared for the different turbulence models. The CFD model was found to be in good agreement with the measurements. Of the turbulence models studied, the Realizable k-ε model showed best agreement with the measured velocity profiles. Popular drag force models proposed in the literature were assessed, as was the influence of inclusion of non-drag forces. Gas flow was found to affect the liquid phase flow in the tank by generating an additional secondary circulation loop in the upper part of the reactor.
Efficiency Improvements in Meta-Heuristic Algorithms to Solve the Optimal Power Flow Problem
Authors: Reddy S. Surender , Bijwe P. R.
Published: October 2016

This paper proposes the efficient approaches for solving the Optimal Power Flow (OPF) problem using the meta-heuristic algorithms. Mathematically, OPF is formulated as non-linear equality and inequality constrained optimization problem. The main drawback of meta-heuristic algorithm based OPF is the excessive execution time required due to the large number of power flows needed in the solution process. The proposed efficient approaches uses the lower and upper bounds of objective function values. By using this approach, the number of power flows to be performed are reduced substantially, resulting in the solution speed up. The efficiently generated objective function bounds can result in the faster solutions of meta-heuristic algorithms. The original advantages of meta-heuristic algorithms, such as ability to handle complex non-linearities, discontinuities in the objective function, discrete variables handling, and multi-objective optimization, etc., are still available in the proposed efficient approaches. The proposed OPF formulation includes the active and reactive power generation limits, Valve Point Loading (VPL) and Prohibited Operating Zones (POZs) effects of generating units. The effectiveness of proposed approach is examined on IEEE 30, 118 and 300 bus test systems, and the simulation results confirm the efficiency and superiority of the proposed approaches over the other meta-heuristic algorithms. The proposed efficient approach is generic enough to use with any type of meta-heuristic algorithm based OPF.
Sampling for variety
Authors: Miestamo Matti , Bakker Dik , Arppe Antti
Published: October 2016

Variety sampling aims at capturing as much of the world’s linguistic variety as possible. The article discusses and compares two sampling methods designed for variety sampling: the Diversity Value method, in which sample languages are picked according to the diversity found in family trees, and the Genus-Macroarea method, in which genealogical stratification is primarily based on genera and areal stratification pays attention to the proportional representation of the genealogical diversity of macroareas. The pros and cons of the methods are discussed, some additional features are introduced to the Genus-Macroarea method, and the ability of both methods to capture crosslinguistic variety is tested with computerized simulations drawing on data inThe world atlas of language structuresdatabase.
Crosslinguistic categories, comparative concepts, and the Walman diminutive
Authors: Dryer Matthew S.
Published: October 2016

In this article, I consider the notions of crosslinguistic categories and comparative concepts as they apply to a diminutive category in Walman, a language in the Torricelli family spoken in Papua New Guinea. I discuss three interpretations of the question of whether the Walman diminutive is a gender. One interpretation is the question whether the Walman diminutive is an instance of a crosslinguistic category of gender. I argue that this interpretation is problematic since it assumes the existence of crosslinguistic categories and I argue that there is no reason to believe that crosslinguistic categories exist, since the similarities among languages can be explained without appeal to crosslinguistic categories. A second interpretation involves a question of how the diminutive fits into the grammar of Walman, whether the diminutive should be considered a third value of a feature in the grammar of Walman which has two clear values, masculine and feminine. I argue that the evidence supports the view that the Walman diminutive is not a gender in this sense. The third interpretation is whether the Walman diminutive is an instance of a comparative concept of gender. But the answer to that question depends on how one defines gender as a comparative concept.
Crosslinguistic categories in morphosyntactic typology: Problems and prospects
Authors: Rijkhoff Jan
Published: October 2016

This article offers a new, transparent method to construe morphosyntactic categories for crosslinguistic research. It avoids the problem of categorial confusion attested in major post-Greenbergian studies in morphosyntactic typology, in particular in probabilistic typological investigations, which tend to mix up semantic and formal criteria and marginalize “statistically insignificant” morphosyntactic variants. These and other problems are avoided by using functional criteria as the starting point in identifying comparable forms and constructions in different languages. Subsequently formal and semantic criteria are employed to arrive at a morphosyntactic category whose members are sufficiently similar in terms of function, form, and meaning.
Surface currents in the Porsanger fjord in northern Norway
Authors: Stramska Malgorzata , Jankowski Andrzej , Cieszyńska Agata
Published: October 2016

We describe surface currents in the Porsanger fjord (Porsangerfjorden) located in the European Arctic in the vicinity of the Barents Sea. Our analysis is based on surface current data collected in the summer of 2014 using High Frequency (WERA, Helzel Messtechnik GmbH) radar system. One of our objectives was to separate out the tidal from the nontidal components of the currents and to determine the most important tidal constituents. Tides in the Porsanger fjord are substantial, with tidal range on the order of about 3 m. Tidal analysis attributes to tides about 99% of variance in sea level time series recorded in Honningsvaag. The most important tidal component in sea level data is the M2 component, with amplitude of ~90 cm. The S2 and N2 constituents (amplitude of ~20 cm) also play a significant role in the semidiurnal sea level oscillations. The most important diurnal component is K1 with amplitude of about 8 cm. The most important tidal component in analyzed surface currents records is the M2 component. The second most important component is the S2. Our results indicate that in contrast to sea level, only about 10-30% of variance in surface currents can be attributed to tidal currents. This means that about 70-90% of variance is due to wind-induced and geostrophic currents.
Climate projections in the Hornsund area, Southern Spitsbergen
Authors: Osuch Marzena , Wawrzyniak Tomasz
Published: October 2016

The aim of this study was to provide an estimation of climate variability in the Hornsund area in Southern Spitsbergen in the period 1976-2100. The climatic variables were obtained from the Polar-CORDEX initiative in the form of time series of daily air temperature and precipitation derived from four global circulation models (GCMs) following representative concentration pathways (RCP) RCP 4.5 and RCP 8.5 emission scenarios. In the first stage of the analysis, simulations for the reference period from 1979 to 2005 were compared with observations at the Polish Polar Station Hornsund from the same period of time. In the second step, climatic projections were derived and monthly and annual means/sums were analysed as climatic indices. Following the standard methods of trend analysis, the changes of these indices over three time periods - the reference period 1976-2005, the near-future period 2021-2050, and far-future period 2071-2100 - were examined. The projections of air temperature were consistent. All analysed climate models simulated an increase of air temperature with time. Analyses of changes at a monthly scale indicated that the largest increases were estimated for winter months (more than 11°C for the far future using the RCP 8.5 scenario). The analyses of monthly and annual sums of precipitation also indicated increasing tendencies for changes with time, with the differences between mean monthly sums of precipitation for the near future and the reference period similar for each months. In the case of changes between far future and reference periods, the highest increases were projected for the winter months.
The pleasure of the non-conceptual: Theory, leisure and happiness in Hans Blumenberg’s philosophical anthropology
Authors: Keiling Tobias
Published: October 2016

The article discusses the place of leisure in Hans Blumenberg’s philosophical anthropology, focusing on “Theorie der Unbegrifflichkeit” (2007). According to Blumenberg, the tradition of philosophical anthropology unjustly reduces human rationality to the attempt of self-preservation. Not only is the actual process of anthropogenesis better described as led by a logic of prevention, not of preservation. Sedentary life, product of preventive behavior, not only secures survival but grants leisure as the condition of culture. Yet cultural practices, although an eminent product of human rationality, cannot be explained by the logic of either self-preservation or prevention. Blumenberg thus argues that within philosophical anthropology, rationality can best be explained in is orientation towards happiness, an orientation encompassing not only preventive, conceptual forms of reason, but also contemplative, non-conceptual uses, such as in myth and mysticism. As the condition for articulating a self-understanding more adequate than self-preservation or prevention, leisure thus assumes a central place in determining human nature. It is in leisure that rationality is experienced as a source of happiness.
Depiction and imagination
Authors: Benovsky Jiri
Published: October 2016

Depiction and imagination are intimately linked. In this article, I discuss the role imagination (as well as inference and knowledge/belief) plays in depiction, with a focus on photographic depiction. I partly embrace a broadly Waltonian view, but not always, and not always for Walton’s own reasons. In Walton’s view, imagination plays a crucial role in depiction. I consider the objection to his view that not all cases of depiction involve imagination – for instance, documentary photographs. From this discussion, two points will emerge: first, we will see that it is an unnecessary mistake to insist too heavily on the fact that photographs are produced in a mechanical way (as opposed to, say, paintings), and second, we will see that the notion of “imagining-seeing”, as it is articulated by Walton, is perhaps too strong and does not entirely do justice to the external character of the role imagination plays here. Focusing mainly on photographs, I then illustrate the view I want to advocate by a series of different cases, where the nature of the role that imagination, knowledge/belief, and inference play in depiction will become apparent.
Back to the 3 R’s: Rights, Responsibilities and Reasoning
Authors: Westphal Kenneth R.
Published: October 2016

Kant’s motto for enlightenment,
Hydrothermal synthesis of a new lead(II) borate (Pb4O)Pb2B6O14-II
Authors: Schönegger Sandra , Wurst Klaus , Heymann Gunter , Huppertz Hubert
Published: October 2016

A new centrosymmetric modification of the lead borate (Pb4O)Pb2B6O14 has been obtained as a side phase through a facile hydrothermal reaction from Pb(BO2)2·H2O, H2O, and KOH as starting materials. The compound (Pb4O)Pb2B6O14-II crystallizes in the space group P1̅ (no. 2) with the lattice parameters a=695.9(3), b=778.0(3), c=1408.3(3) pm, α=97.35(1)°, β=100.39(1)°, and γ=103.02(1)°. The structure consists of anti-parallel arranged B6O14 chains and isolated oxygen-centered OPb4 tetrahedra. The compound Pb6B12O21(OH)6 constitutes the major phase of the synthesis, as verified through a Rietveld analysis. The characterization of (Pb4O)Pb2B6O14-II is based on a Rietveld analysis, single-crystal X-ray diffraction data, and FT-IR spectroscopy.
Density Functional Theory Calculations, Spectroscopic (FT-IR, FT-RAMAN), Frontier Molecular Orbital, Molecular Electrostatic Potential Analysis of 5-Fluoro-2-Methylbenzaldehyde
Authors: Iyasamy Sehar , Varadharajan Krishnakumar , Sivagnanam Sivakumar
Published: October 2016

The FT-IR and FT-Raman spectra of 5-fluoro-2-methylbenzaldehyde (5F2MB) have been recorded in the regions 4000–400 cm−1and 4000–100 cm−1, respectively. Using the observed FT-IR and FT-Raman data, a complete vibrational assignment and analysis of the fundamental modes of vibrations of the compound were carried out. The optimum molecular geometry, vibrational frequencies and Raman scattering activities were calculated by density functional theory with B3LYP/6-311+G** basis sets. A close agreement was achieved between the calculated and observed frequencies by refinement of scale factors. Unambiguously normal modes of vibrational assignments have been made with the help of the GUASSVIEW 5.0 program and the potential energy distribution (PED) calculated by the density functional theory calculations. Natural bonding orbital (NBO) analyses were carried out to discuss the stability of the molecule. The molecular electrostatic potential (MEP) map and electron density map were drawn and analyzed. Using nuclear magnetic resonance (NMR) analysis, the chemical shifts of hydrogen atoms and carbon atoms were calculated. The charge distribution, Mullikan atomic charge values and HOMO–LUMO energy have been calculated to explore the reasons for the change in biological activity. Furthermore, the first hyperpolarizability and the dipole moment of the molecule have also been calculated.