bluuebunny/crossref_metadata_2025 huggingface dataset:
Prevalence and Molecular Characterization of Macrolide Resistance in Clinical Isolates of Beta Hemolytic Streptococci from a Tertiary Care Teaching Hospital in Kerala, India
Authors: George Ann , Jose Rosmi , Valsan Chithra
Published: December 2023

Background: Beta-hemolytic streptococci (BHS) are responsible for both invasive and noninvasive infections, and the preferred treatment for these infections is penicillin due to the distinctive characteristics of these bacteria. However, in patients who cannot tolerate β-lactam antibiotics, macrolides and clindamycin are important alternative options for treating BHS infections. This study aimed to analyse the pattern of macrolide resistance among clinical strains of beta-hemolytic streptococci (BHS).
Methods: Beta hemolytic streptococci isolated from clinical specimens during December 2018 to May 2020 were included in this study. Identification of the isolates were done by conventional and Vitek 2 method. All isolates were subjected to serogrouping. Antibiotic susceptibility testing done by disc diffusion method. Genes encoding macrolide resistance were detected by conventional multiplex polymerase chain reaction.
Results: A total of 129 beta hemolytic streptococcal isolates were obtained which included 27 S. pyogenes (20.9%), 77 S.agalactiae (59.7%), 23 S.dysgalactiae spp equisimilis (17.8%) and one isolate of S.anginosus and S. porcinus each (0.8%). Erythromycin, clindamycin, quinuprisitn and tetracycline resistance were found to be 20.2%, 12.1%, 16.3% and 51.2% respectively. Among the 26 erythromycin resistant isolates, 12(46.2%) were inducible clindamycin resistant phenotype. Out of 26 erythromycin resistant isolates, 7(26.9%) isolates were harbouring erm(A) gene, 10(38.5%) erm(B) and 9(34.6%) mef(A) gene.
Conclusion: Our study highlights the importance of routine antibiotic susceptibility testing for betahaemolytic streptococci, as well as the detection of inducible resistance to prevent therapeutic failure.
Comparative Evaluation of Serological, ELISA and Molecular Tests in Diagnosis of Brucella abortus in Human Serum
Authors: Ghanbari Fereshteh , Bashi Zadeh Fakhar Haniyeh , Alamian Saeed , Shaghaghi Babak
Published: December 2023

Background: Brucellosis is one of the most prevalent and common diseases between humans and animals.Prompt diagnosis and timely treatment of this disease can prevent many complications. In this regard, this study aims to comparatively evaluate ELISA, PCR and serological methods to identify Brucella abortus.
Methods: In this study, the serum of 100 patients referred to Tonekabon private laboratory from July 2020 to January 2021 was examined by PCR, ELISA and Wright, Coombs Wright, and 2ME methods for the detection of Brucella abortus.
Results: In this study, the mean age of the sample was 43.3 ± 18.2 of which 21% were infected with Brucella abortus according to the above serological methods. According to ELISA test, 22% of the samples were IgM, 6% of the samples were IgG and 16% were PCR positive. Kappa agreement coefficient in Wright and Coombs Wright test and 2me were significant (P <0.001). Serological diagnostic indices and ELISA sensitivity were 68.75% and 68.75%, respectively. The lowest prediction rate of Brucella abortus among diagnostic methods was related to Elisa (IgM). Based on Fisher's exact test, there was no significant relationship between the percentage of Brucella abortus positive PCR cases and age, sex, previous history of infection with Brucella, fever, body aches and dairy consumption.
Conclusion: Based on the results of our study, the accuracy of all methods is comparative and the lowest accuracy is related to Elisa (IgM) which has a lower level of predictability than other methods. The highest level of prediction belonged to Wright and 2me tests.
Decolonial health literature can increase our thinking about ethics dumping
Authors: Ewuoso Cornelius
Published: December 2023

This article draws on the underexplored or novel accounts of inclusion and the moral accounts of decolonization in African health decolonial literature to increase our understanding of how ethics dumping manifests in health research partnerships, and what more ought to be done to eliminate this phenomenon. African decolonial health literature proposes “inclusion that matters” – conceptualized as substantial, respectful and deep engagement with African agency – as a solution to end domination or mitigate the “appearance” of inclusion. Based on this supposition, the harm of ethics dumping – and I demonstrate how – is that it fails to engage the agency of Africans, and listen to or echo their voices in health and health research collaborations on the continent, or research collaborations that have significant implications for them. This account of inclusion can usefully increase our thinking about ethics dumping, which is ultimately and in several ways a failure to practice responsible science. Research is required to increase our understanding of what could reasonably constitute responsible science from a variety of perspectives.
Acute Leukemia in A Young Female Adult Presenting for Care in A Resource Constrained Setting
Authors: Mwizabi Simakando A. , Musuka Brian , Mwape Celine , Mulenga Audrey , Mweene Mutale , Maliko Catherine , Maksoud Gamal , Chimese Mwinsa , Zulu Mabvuto , Chinkoyo Sebastian , Nyirenda Christopher
Published: December 2023

Background: Acute leukemia is a rare malignant disorder arising from an abnormal proliferation of hematopoietic precursor cells. With advances in the management of leukemia, patients of acute leukemia have high chances of achieving adequate remission and survival. However, due to late presentation, diagnosis and treatment, the disease has significantly contributed to high morbidity and mortality especially in resource limited settings.
Method: A comprehensive history and physical examination was taken, coupled with literature review. Various rationale for each intervention and recommended interventions unavailable in our setting were noted.
Results: Early diagnosis and treatment of leukemia and its complications is a major public health concern for which the general public needs to be educated on. In this case report, material and human resource constraints in our setting may contribute towards the patient’s poor clinical outcome.
Conclusion and recommendations: Acute leukemia is a manageable disorder provided the availability of appropriate resources and interventions being implemented early. There is therefore need to equip our health facilities and personnel with resources towards early clinical detection, diagnosis and treatment which measures are essential for successful management and prevention of unwanted complications.
Adsorptive Removal of Volatile Organic Compounds from Industrial Effluent Using Synthesized ZnO-CA Composite Base Adsorbent
Authors: BAMİGBOYE Mercy , KURANGA Ayinla Ibrahim , BENJAMİN Orimolade , MUSTAPHA Ayuba , OJO Olayinka , WASİU Jamiu , ABDULGANİY Aishat A , OBA Hameeda Sinmiloluwa
Published: December 2023

In this study, a composite adsorbent consisting of ZnO nanoparticles and cellulose acetate nanoparticles was prepared. The composite was extensively characterized through Scanning electron microscopy (SEM), Transmission Electron Microscopy (TEM), Energy Dispersive X-ray Spectroscopy (EDX), and Brunnaeur Emmet Teller analysis (BET). Batch adsorption experiments were carried out to study the effects of concentration of adsorbate (10- 80 mL), dose of adsorbent (0.1 – 1 g), pH(3-13), contact or exposure time (30-180 minutes) and temperature(30 - 70℃) on the removal of benzene and toluene using the synthesized adsorbent. The pseudo-second-order model well described the kinetics of adsorption studied, and Langmuir's isotherm best described the isotherm modeling of the adsorption data. Thermodynamic studies revealed that all the adsorption processes are feasible, endothermic, and spontaneous. The prepared adsorbent is suitable for removing benzene and toluene from wastewater.
Synthesis And Characterization of Two New Hofmann-Type-Like Compounds From Some Alkali Metal Atoms And Glycine Anhydride
Authors: KARTAL Zeki , ŞAHİN Zarife Sibel
Published: December 2023

In this study, two new compounds with their closed formula, C8H10K2N6NiO4, and C8H10Na2N6NiO4, were synthesized, the first in crystal form and the second in powder form. Various properties of these compounds were characterized by SC-XRD and FT-IR methods. Theoretical information about the compounds was obtained with the help of the Gaussian 03 program. The molecular formula that best reflects the structural properties of this first 3D compound, which is in crystalline form and has polymeric properties, can be given as {K2(GA)(H2O)2[Ni(CN)4]}n. With a similar thought, it can be suggested that the molecular formula that best reflects the structural properties of the second 3D compound in powder form and with polymeric properties will be {Na2(GA)(H2O)2[Ni(CN)4]}n. The asymmetric unit of the {K2(GA)(H2O)2[Ni(μ4-CN)4]}n compound is composed of a half Ni(II) ion, one K(I) cation, two cyanide ligands, a half GA ligand molecule, and one bounded water ligand molecule. The structure of the compound, which consists of 3D polymeric chains, is formed by various bonds between the GA molecule, K(I) cations, water ligand molecules, and Ni(CN)4 ions.
Performance and Safety Evaluation of Polypropylene Mesh Used in Inguinal Hernia Repairs
Authors: BARLAS Aziz Mutlu , ALTINER Saygın
Published: December 2023

Aim: This study aimed to compare the data of patients who underwent open tension-free hernia repair using polypropylene mesh with the data obtained from the literature, and to evaluate the efficacy and safety of this mesh in the early postoperative period. The results of this study will provide additional data to the literature in terms of comparing different mesh materials.
Material and Methods: In this cross-sectional, and observational study, the early postoperative-period data of 96 patients who had undergone standard Lichtenstein tension-free hernia repair using polypropylene mesh in a tertiary-level hospital, using polypropylene mesh were evaluated and compared with the data obtained from the literature.
Results: The mean age of patients was 58.59±13.82 (range, 20-83) years. The median length of hospital stay was 1 (range, 1-4) day. The median of visual analogue scale (VAS) scores was 2 (range, 0-4) for the day of surgery, 0 (range, 0-4) for postoperative day-1, and 0 (range, 0-2) for postoperative day-2. A total of 6 complications developed in 5 of the patients, 3 (3.13%) were hematoma, 2 (2.08%) were wound site infections, and 1 (1.04%) was seroma. In one patient, both hematoma and wound infection were determined. No mortality was encountered.
Conclusion: Polypropylene mesh could be used effectively and safely in groin hernia operations. Although some complications with the use of synthetic mesh materials have been reported since the introduction of these materials into clinical use, none of these have yet been considered as conditions that will adversely affect the use of polypropylene mesh.
Diretrizes para mapeamento de formas de relevo tecnogênicas no Sistema Brasileiro de Classificação do Relevo (SBCR)
Authors: Moura Nina Simone Vilaverde , Silva Telma Mendes da , Caccia-Gouveia Isabel Cristina Moroz , Peixoto Maria Naíse de Oliveira , Felippe Miguel Fernandes , Oliveira Antônio Manoel dos Santos , Peloggia Alex Ubiratan Goossens , Nolasco Marjorie Csekö
Published: December 2023

O objetivo deste trabalho é discutir a particularidade da classificação das formas de relevo tecnogênicas, isto é, derivadas direta ou indiretamente do agenciamento humano, por meio dos estudos realizados no âmbito do Sistema Brasileiro de Classificação do Relevo. Tais formas, como expressão dos terrenos tecnogênicos, são analisadas por meio do método morfoestratigráfico, com base em seus processos de formação, configuração e materiais constituintes. Tal aplicação levou aos seguintes resultados em termos de classificação, em dois níveis básicos: (1) Categorias, definidas segundo a dinâmica geomorfológica seja aditiva (elevações ou superposições), subtrativa (cicatrizes ou depressões) ou conservativa (corrugações e equiformas), esta última diferenciada pela ocorrência ou não de alteração topográfica; (2) Tipos, diferenciados conforme o agenciamento humano, seja direto (tecnoformas), ou indireto (geotecnoformas), ou ainda, segundo o caráter superficial ou profundo do processo modificador (no caso das equiformas). Conclui-se que as formas tecnogênicas constituem uma categoria geomorfológica particular, passível de análise, classificação e mapeamento por métodos próprios, e sua referenciação taxonômica é considerada em uma abordagem transversal, observando-se sua maior expressão ao nível do sexto, do quinto e do quarto táxons de Ross (1992), podendo ocorrer variações nesta classificação frente às dimensões da intervenção da agência humana.
Is wine an emotional object? Measurements of the subjective and automatic components of emotions in a wine-tasting situation
Authors: Elali Inès , M’Bailara Katia , Sanders Victoria , Riquier Laurent , De Revel Gilles , Tempère Sophie
Published: December 2023

Wine is often described with emotional terms, such as surprising, disappointing, or pleasant. However, very little has been done to understand the role of emotions in wine tasting and characterise this link between emotions and wine. Many studies have looked at the extrinsic factors that can improve the emotional experience of tasters when discovering a wine, but few have been carried out on the emotional impact of the organoleptic characteristics of wines. The present study aims to determine if the automatic component of emotion has a measurable output (motor and physiological) when tasting wine. If so, does wine tasting induce a concomitant activation of the different components of emotion, such as subjective feelings or physiological and motor responses?Sixty-five connoisseurs tasted seven different red Bordeaux wines with different sensory properties and quality levels pre-defined by wine experts. Emotions were measured using subjective (subjective feelings measurement using self-declarative questionnaires) and automatic (physiological measurements such as skin conductance and heart rate, or motor measurements through facial expressions) methods. The results showed that there was a measurable physiological and motor emotional output in wine tasting. The results also highlighted that changes in the autonomic nervous system in a wine-tasting situation are structured around the dimensions of pleasantness and arousal. Motor measurements taken through facial expressions showed a marginally significant difference between wines providing pleasant and unpleasant emotions for the activation intensity of action units. The relationships established between these components, as well as their concomitant activation, allow us to define wine as an emotional object.
ECONOMIC BURDEN OF COVID-19 IN THE REPUBLIC OF BASHKORTOSTAN
Authors:   Ufa University of Science and Technology, TIMIRYANOVA VENERA M. , LAKMAN IRINA A. ,   Ufa University of Science and Technology, VALISHIN DAMIR A. ,   Bashkir State Medical University, GAREEVA DIANA F. ,   Ufa University of Science and Technology, SULTANOV BULAT R. ,   Ufa University of Science and Technology, ZAGIDULLIN NAUFAL SH. ,   Ufa University of Science and Technology
Published: December 2023

Abstract. Introduction. Extent of social losses due to the COVID-19 pandemic is still evaluated incompletely fully assessed despite its declared end. Aim. To study the socioeconomic burden of the novel coronavirus (COVID-19) in the Republic of Bashkortostan. Materials and Methods. In this study, we used the method of accounting for the economic burden caused by hospitalizations, sick leaves, and deaths. Four disease severity levels (mild, moderate, severe, and critical) and two treatment options (inpatient or outpatient) were considered. Direct costs were evaluated using the data provided by the Tariff Agreement on Compulsory Medical Insurance in the Republic of Bashkortostan. Indirect losses were evaluated considering the times of the patients’ incapacity to work and assessing the amounts of “underproduced” Gross Regional Product due to their premature deaths. Results and Discussion. The results obtained indicate that total direct medical costs related to the diagnosis and treatment of coronavirus infection increase annually, despite the reducing costs of each treatment stage. Based on published data alone, the three-year direct costs amounted to 0.3 billion rubles for outpatient treatment, 7.4 billion rubles in hospitals, and 4.6 billion rubles for PCR tests. In the loss structure, significant are indirect costs associated with incapacity periods (4.7 billion rubles) and mortality (2.3 billion). Conclusions. COVID-19 pandemic has led to large socioeconomic losses.
ANEMIA OF VARYING SEVIRITY DEGREES IN PATIENTS WITH STEMI
Authors:   Kazan State Medical University, KHAMADULLINA ILIDA F. , KHUSAINOVA ALIA A. ,   Kazan State Medical University, IVANTSOV EVGENIY N. ,   Kazan State Medical University, KHASANOV NIYAZ R. ,   Kazan State Medical University
Published: December 2023

Abstract. Introduction. Anemia associated with cardiovascular diseases, particularly with myocardial infarction, is a significant risk factor for adverse outcomes. At the same time, it is poorly known about the issue of acute blood circulatory disturbances during myocardial infarction in the setting of anemia of varying severity degrees. Our aim was to study the at-admission hemoglobin levels in patients with ST-elevation myocardial infarction with favorable and fatal outcomes of hospitalization. Material and Methods. We selected 177 records of patients with fatal outcomes of and 380 records of patients discharged with favorable outcomes of ST-elevation myocardial infarction from the emergency departments for patients with acute coronary syndrome of State Clinical Hospital 7, Kazan. The study included 349 men and 208 women aged 32 to 96 years, median age being 67 (58–76) years. Results and Discussion. Incidence of anemia (hemoglobin lower than 130 g/l in men and 110 g/l in women) in the group of patients under study with favorable and fatal hospitalization outcomes was significantly different and amounted to 8.7% and 18.1%, respectively (p = 0.001). Probability of unfavorable outcomes in the group of patients with anemia was 2.32 times higher than that in the group of patients without anemia, the differences in odds were statistically significant (95% CI: 1.38 - 3.92; p = 0.001). Moderate and severe anemia (Hb <90 g/l) was more common in patients with unfavorable outcomes than in patients with favorable outcomes of hospitalization, i.e., in 43.8% and 15.2% of cases, respectively. Odds of an unfavorable outcome were 4.35 times higher in patients with moderate to severe anemia than in patients with mild anemia, the difference in odds was statistically significant (95% CI: 1.34 - 14.08, p = 0.015). Conclusions. Anemia in an ST-elevation myocardial infarction patient is associated with a 2.32 greater chance of an unfavorable outcome. A decrease in hemoglobin level below 90 g/L in a patient with ST-elevation myocardial infarction is associated with a 4.35 times greater chance of an unfavorable outcome.
The experience of caregiving for children with rare musculoskeletal conditions: A qualitative study in Arthrogryposis Multiplex Congenita
Authors: Elekanachi Rose Uzoma , Lajoie Ariane , Tavukcu SeyhanSena , Snider Laurie , Dahan-Oliel Noemi
Published: December 2023

Background Arthrogryposis Multiplex Congenita (AMC) is a rare musculoskeletal condition with a global health impact. It imposes significant financial burdens on caregivers, affecting them directly, indirectly, and psychologically. Caring for a child with AMC is complex due to their mobility limitations and frequent hospitalizations. Other challenges experienced by caregivers include, but are not limited to, financial strain, job changes, abandonment, and changes in interpersonal relationships. Hence, our study was aimed at exploring the experience of caregivers of children with AMC. Methods This study is part of a global mixed method study. Over 100 caregivers of children aged 0–21 years with AMC participated in the quantitative aspect of this mixed-method study which involved responding to a validated cost of care survey on Qualtrics. Of the 100 participants, 13 caregivers consented to be part of the qualitative aspect of this study which involved a 60-minute semi-structured interview. Individual interviews were semi-structured, conducted remotely with open-ended questions exploring a deeper understanding of the different direct and indirect costs and their impact on the caregivers' lives and caregiving experience. Interviews were subsequently transcribed; a coding scheme was developed drawing from both existing literature and the content of the interviews. The qualitative data were then inductively and deductively analyzed using the coding scheme on the qualitative data analysis software (NVivo). Results and Conclusion Five themes describing the experience of caregivers of children with AMC emerged from the analysis of the qualitative data: 1. Impact of caregiving experience; 2. Cost of childcare; 3. Support system for care; 4. Managing and navigating care; 5. Supporting child’s growth and development. Alongside these themes, recommendations shared by the caregivers included the need for support groups and providing support for youth to prepare them for adolescence. These findings can inform resource allocation, policymaking, and support services for children with rare conditions.
Differential Perspectives Between miRNA and lncRNA in Light of Biogenesis and Functions: A Review
Authors: Tewari Shilpa , Kaur Bhawanpreet , Rana Kanwaljit , Mukhopadhyay Chandra Sekhar
Published: December 2023

The central dogma is suggested that deoxyribonucleic acid is translated into ribonucleic acid (RNA) and then into protein. It is considered that 2–3% of the genomic DNA in a functionally active cell, is transcribed to protein-coding RNA. The presence of noncoding transcripts has been neglected many a time as cellular DNA and transcript noises, however, increasing proof proposes that a very important part of these non-coding transcripts is functionally effective as RNA molecules. The non-coding transcripts of up to 100 bases are known as small non-coding RNA that comprises tRNA, miRNA, snoRNA, piwi-interacting RNA (pi-RNA), etc. Interestingly, rRNA features about 6.9 kb, though these are not considered long-non-coding RNAs. However, RNA molecules that are over 200 bases long (ranging between 0.8 to 10 kb) are known as long non-coding RNA (lncRNA). It does not have open reading frames (with some exceptions), 3`- untranslated regions (3’-UTRs), and these RNAs are devoid of any translation-termination regions. However, these may be capped, spliced, and polyadenylated as RNA molecules and play a major role in factor regulation, neoplastic cell invasion, chromatin granule transforming, and cell differentiation. Downregulation of lncRNA is responsible for numerous diseases in mammals. miRNAs are mature transcripts of 22 nt in length and function as antisense regulators of other RNAs. They play role in post-transcriptional factors and are involved in differentiation, proliferation, immune response, cell growth, and caspase-mediated cell death. Downregulation in miRNA expression has a necessary role in many diseases, together with cancers.
Nigeria’s Foreign Policy and Insecurity: Addressing the Missing Links and Reoccurring Issues
Authors: Chioke Stephen Chinedu , Umeokafor Chibuike Chris
Published: December 2023

Insecurity is the biggest problem in Africa and nothing meaningful has been done by several sovereign states in Sub-Saharan Africa to stem the tide and its effects on nations all over the region. To this end, security has risen to be the dire need to be considered through the lens of foreign policy as an integral part of public administration and governance in Nigeria. Therefore, this paper specifically explored the missing links that gave rise to the problem of insecurity from foreign policy perspective; and the reoccurring issues that the ebb and flow of her foreign policy posed to Nigerian public space with major focus on Buhari’s Administration. Secondary data was employed to analyse the broad and specific objectives of this paper through a descriptive and explanatory method. The missing link in Nigeria’s foreign policy and security challenges spotted in the analysis are political ideology, globalization, poorly unchecked borderlands, and high rate of migration of criminal elements. The paper discovered some reoccurring issues in Nigeria’s foreign policy and security challenges. The paper concluded that all is not well with the country, because while the protectionist policy under President Buhari to a great extent blocked foreign trade, it left security of borderlands at the mercy of corrupt security personnel. Based on this, all hands must be on deck to exterminate the current tide in the wave of insecurity ravaging the country at all costs.
LEADERSHIP PRACTICES OF SUBJECT GROUP HEADS (SGH) AS PERCEIVED BY SENIOR HIGH SCHOOL (SHS) TEACHERS: A QUANTITATIVE ACTION RESEARCH APPROACH
Authors:   Sorsogon State University, Sorsogon City Campus, Sorsogon, Philippines., Ann T. Dollentas Jamie , Julius B. Foster Jan ,   Sorsogon State University, Sorsogon City Campus, Sorsogon, Philippines., Recto H. Burton Ralph ,   Sorsogon State University, Sorsogon City Campus, Sorsogon, Philippines., Crestina C. Dolorica Maria ,   Sorsogon State University, Sorsogon City Campus, Sorsogon, Philippines., D. Sano Sheryll ,   Sorsogon State University, Sorsogon City Campus, Sorsogon, Philippines., S. Janer PhD Susan ,   Sorsogon State University, Sorsogon City Campus, Sorsogon, Philippines.
Published: December 2023

Enhancing the leadership of subject group heads lies in the recognition of the crucial role that effective leadership helps improve and promote positive outcomes for both teachers and students. This research was conducted to identify leadership practices of Subject Group Heads (SGH) along communication skills, decision-making abilities, support for professional development, and their overall effectiveness in managing the subject groups and evaluate how these insights can be used to provide recommendations for enhancing their leadership effectiveness towards the improvement of the Senior High School Programs in Gallanosa National High School (GNHS). This study used a quantitative action research approach, to promote collaboration between researchers and practitioners and ensure informative and actionable findings. A survey with a 5-point Likert scale questionnaire was done. Its reliability was confirmed with an excellent internal consistency of 0.90 using Cronbachs Alpha. The results demonstrated that the effectiveness of communication in schools facilitates effective leadership and promotes a positive learning environment.Also, decision-making skills are crucial in enhancing student achievement and addressing challenges. Supporting the professional development of Teachers fosters a culture of continuous learning and collaboration. However, it is notable that some areas of concern focus on conflict and challenge management, giving timely and constructive feedback, and fostering unity and collaboration. As a result, it is recommended to improve leadership practices by fostering effective communication, decision-making skills, supporting teacher professional growth, and managing subject groups effectively with unity and collaboration provide quality educational experience for students, teachers, and the community.
RISQUESPSYCHOSOCIAUX ET MILIEU PROFESSIONNEL: APPROCHE PSYCHOSOCIALE
Authors:   Chercheur doctorante sous la Direction du Pr. Ahmed El Bouazzaoui a la Faculte des Lettres et Sciences Humaines, au seinde lequipe de Recherche en Psychologie Sociale et Clinique et du Travail (PSCT)de Rabat au Maroc., Bennamate Safa , El Bouazzaoui Ahmed ,   Enseignant chercheur a laFaculte des Lettres et Sciences Humaines de Rabat au Maroc et Directeurde lequipe de Recherche en Psychologie Sociale et Clinique et du Travail (PSCT).
Published: December 2023

The objective of this article was to investigate various issues related to the world of work through the lens of social categorization theory, and more specifically, that of social representations. The aim was to identify the most prevalent social risks in the professional environment by administering questionnaires to randomly selected workers. Following this study, we were able to observe the significance of the emotional aspect in the professional domain.
ENDOMETRIOTIC SCAR AFTER HYSTEROTOMY-A RARE CASE
Authors:   Specialist Obstetrics & Gynaecology Department, Hatta Hospital, Dubai Health, United Arab Emirates., Naz Huma , Siddique Saadia ,   Senior Specialist Obstetrics & Gynaecology Department, Hatta Hospital, Dubai Health, United Arab Emirates., Ahmidat Adel ,   Consultant, Obstetrics & Gynaecology Department, Hatta Hospital, Dubai Health, United Arab Emirates., Khalifa Jinan ,   Consultant & Head of Department Obstetrics & Gynaecology, Hatta Hospital, Dubai Health, United Arab Emirates., Fatima Iraj ,   Medical Student, 3rd Year MBBch, Dubai Medical College, United Arab Emirates.
Published: December 2023

The presence of endometrium outside the uterine cavity is known as endometriosis. Scar endometriosis is an uncommon type of extra-pelvic endometriosis, that is usually confused with other surgical or dermatological conditions leading to delay in diagnosis.Abdominal wall or cutaneous endometriomas are quite uncommon with an incidence of less than 1%. The symptoms are nonspecific, typically involving abdominal wall pain at the incision site at the time of menstruation. It commonly follows obstetrical and gynecological surgeries.We are reporting a scar endometriosis case, involving the rectus sheath which presented as cyclical painful previous hysterotomy scar.
THE IMPACT OF E-COMMERCE ON TRADITIONAL RETAIL: A COMPREHENSIVE ANALYSIS OF ECONOMIC, SOCIAL, AND POLICY DIMENSIONS
Authors:   The Aravali School., Goel Manya
Published: December 2023

This research aims to investigate the multifaceted effects of the growing e-commerce sector on traditional retail businesses, considering economic, social, and policy dimensions. The study will explore the economic implications for both e-commerce and brick-and-mortar retailers, analyzing factors such as market dynamics, pricing strategies, and consumer behavior. Additionally, it will examine the social consequences, including changes in employment patterns and the overall retail landscape. Furthermore, the research will evaluate the role of government policies in shaping the e-commerce and traditional retail sectors, addressing issues like taxation, regulatory frameworks, and competition policies. By adopting a comprehensive approach, this study seeks to provide valuable insights into the evolving relationship between e-commerce and traditional commerce, offering practical recommendations for businesses and policymakers alike.
CURRENT STATUS OF ETHONOPHARMACOLOGY OF MEDICINAL PLANTS IN INDIA: A COMPREHENSIVE ANALYSIS
Authors:   Department of Botany, Faculty of Sciences&IT, Madhyanchal Professional University, Ratibad, Bhopal, Madhya Pradesh, India., Kumar Mahato Parimal , Mohabe Satish ,   Department of Botany, Faculty of Sciences&IT, Madhyanchal Professional University, Ratibad, Bhopal, Madhya Pradesh, India., Kumar Mandal Ashok ,   Department of Botany, P.K. Roy Memorial College, Binod Bihari Mahato Koylanchal University, Lohar Kulli, Saraidhella, Dhanbad, Jharkhand, India.
Published: December 2023

This in-depth study examines the current situation and ethnopharmacology of Indias medicinal plants, shedding light on the countrys rich biodiversity, traditional knowledge, and cutting-edge scientific research into these invaluable assets. Indias many ecologists have endowed the country with a remarkable array of plant species used in traditional medicine. Researchers in the field of ethnopharmacology have uncovered a wealth of indigenous wisdom that demonstrates the mutually beneficial relationship that exists between human communities and their natural environments. Modern scientific research has proved the potential pharmacological characteristics of these plants, bridging the gap between traditional and modern medicine. The richness of this species is threatened by factors such as over exploitation, habitat degradation, and climate change, making conservation efforts imperative. Regulatory frameworks have been established to ensure the quality and safety of herbal products, and continual harmonization between traditional and modern medical practices is necessary to achieve this goal. The significance of Indias medicinal plant resources necessitates collaborative research and commercial endeavours for the benefit of global health. The findings of this study stress the need of a comprehensive approach that integrates traditional wisdom, cutting-edge scientific understanding, conservation efforts, and vigilant regulation. Sustainable use and conservation of these invaluable resources require collaboration between different parties, and protecting Indias medicinal plant heritage is not only a matter of national pride but also has important implications for the future of biodiversity and healthcare around the world.
TRAITEMENT DU PHOSPHATE NATUREL DE LA TAPOA (NIGER) PAR DES ACIDESMINERAUX ET ORGANIQUES
Authors:   Departement de Chimie, Faculte des Sciences et Technologie, Universite de Niamey, BP 10662, Niamey, Niger., Mahamane Sani Ousmane , Souley Abdoul Aziz Mamane ,   Departement de Chimie, Faculte des Sciences et Technologie, UniversiedAgadez, BP 199, Agadez, Niger., Gondah Ismaila Abdou ,   Departement de Chimie, Faculte des Sciences et Technologie, UniversiedAgadez, BP 199, Agadez, Niger., Adamou Zanguina ,   Departement de Chimie, Faculte des Sciences et Technologie, Universite de Niamey, BP 10662, Niamey, Niger., Ibrahim Natatou ,   Departement de Chimie, Faculte des Sciences et Technologie, Universite de Niamey, BP 10662, Niamey, Niger.
Published: December 2023

This study propose away for the development of hardly soluble natural phosphate. Thusitwascarried out, the dissolution of natural phosphate from Tapoa (Niger) in solutions of mineralacids (nitricacid and sulfuricacid) and in solutions of organicacids (citricacid and ethylene diamine tetraacetic EDTA) in function of pH and attack time. The resultsobtainedshowedthat the maximum rate of dissolvedphosphorus as a percentage of phosphoric anhydride (P2O5) is 14.08% and 15.99% respectively in solutions of nitricacid and sulfuricacid at the concentration of after 7 hours of attack. In organicacid solutions, the dissolution rate is 4.67% and 5.17% respectively in citricacid and EDTA solutions at the same concentration. In addition, the dissolution rate decreaseswhen the acid concentration decreaseswhileit tends to increasewith the attack duration regardless of the acid solution used (mineral or organic). Also, this dissolution rate isalmostzero in solutions of organicacidswhen the concentrationis.
LEGAL PROTECTION OF WORKERS AND TRADE UNIONS IN THE CONTEXT OF COMPANY ACQUISITIONS
Authors:   Lampung University., Riza Amalia Kasmawati , Sunaryo,
Published: December 2023

Changes in company ownership sometimes cause employers to ignore relations with workers and trade unions. Entrepreneurs do not realize that there is an employment agreement that must be maintained intact before the process of transferring company ownership. This must be taken into account because the old owner has a work relationship which is regulated through a work agreement or collective work agreement.This research aims to examine how the law provides protection for workers and also labor unions when a company acquisition occurs. This research uses normative methods. The conclusion of this research is that the rights of workers and trade unions in foreign companies that change ownership are protected by law. If we look at Law No. 13 of 2003 concerning Employment, protection for workers is contained in the provisions of Article 163 which states Employers can terminate employment relations with workers/laborers in the event of a change in status, merger, consolidation or change in ownership of the company and workers/laborers. is not willing to continue the employment relationship, then the worker/laborer is entitled to 1 (one) severance pay in accordance with the provisions of Article 156 paragraph (2), 1 (one) time period of service compensation as stipulated in Article 156 paragraph (3) and compensation money in accordance with the provisions in Article 156 paragraph (4).
EVALUATION OF WEBINAR FOLLOW-UP BY PEDIATRIC RESIDENTS DURING THE PERIOD OF COVID 19
Authors:   Neonatal Intensive Care Unit, Mother-Child Hospital, CHU Mohammed VI, Marrakech, Morocco., Danaoui K. ,   Childhood, Health and Development Research Unit, Faculty of Medicine and Pharmacy, Cadi-Ayyad University, Marrakech, Morocco., Bennaoui F. ,   Neonatal Intensive Care Unit, Mother-Child Hospital, CHU Mohammed VI, Marrakech, Morocco.,   Childhood, Health and Development Research Unit, Faculty of Medicine and Pharmacy, Cadi-Ayyad University, Marrakech, Morocco., El idrissi Slitine N. ,   Neonatal Intensive Care Unit, Mother-Child Hospital, CHU Mohammed VI, Marrakech, Morocco.,   Childhood, Health and Development Research Unit, Faculty of Medicine and Pharmacy, Cadi-Ayyad University, Marrakech, Morocco., Maoulainine F.M.R. ,   Neonatal Intensive Care Unit, Mother-Child Hospital, CHU Mohammed VI, Marrakech, Morocco.,   Childhood, Health and Development Research Unit, Faculty of Medicine and Pharmacy, Cadi-Ayyad University, Marrakech, Morocco.
Published: December 2023

Since the WHO declared COVID-19 a global pandemic, several countries have applied social distancing rules including quarantine. In Morocco, this measure has been in force since March 20, 2020. This has forced the closure of several scientific activities, including pediatric congresses and scientific days. To compensate for this, webinars have taken center stage in this time of global pandemic. The aim of our work is to assess pediatric residents perception of continuing medical education via webinars during COVID-19, and to find out how they see the organization of future scientific events. A survey was carried out among pediatric residents at CHU Med VI in Marrakech via the Google Forms platform. The average age of residents was 30, with a predominance of women. 44% of pediatric residents were bothered or very bothered by the suspension of face-to-face scientific events. A total of 33% of pediatric residents attended an average of 15 webinars during the pandemic, and 24% of them found the experience interesting. Overall, the reasons for not viewing the webinars were, in 28% of cases, coincidence with on-call duty and, in 16%, unsuitable scheduling. The majority were satisfied with the content presented, the choice of webinar themes and the choice of speakers. The worldwide pandemic of COVID-19 has put the spotlight on webinars, which are an interesting alternative for continuing medical education but can never replace a face-to-face scientific meeting, according to the residents.
¿Por qué estudiar la comunicación actual desde la perspectiva de la retórica digital?
Authors: López Aguirre José Luis , Fernández Fernández Eduardo José , Gómez Aguilera Blanca Nahayeli
Published: December 2023

Este artículo presenta el concepto de retórica digital como un término novedoso y esencial para el estudio teórico y metodológico de los usos y aplicaciones actuales del discurso que discurre en la era digital y que es expresado en entornos populares como las redes sociodigitales. Asimismo, se explica al lector la concepción de este constructo interdisciplinar y su contribución al campo de estudio, se ofrece una reflexión crítica sobre los estudios de la retórica en distintas capas que comprenden desde su trascendencia histórica, conceptual, técnica y multidisciplinar en el análisis de los discursos y prácticas humanas y sociales mediadas por los distintos lenguajes, hasta su posibilidad de reinvención para motivar otras interrogantes sobre las nuevas funciones retóricas en la actualidad, que son aplicadas a los distintos mensajes y niveles de la comunicación digital.
Food Preferences in Two Detritivore Species: Laboratory Choice Tests Using Leaf Litters of Different Tree Species
Authors: Makulec Gabriela , Ilieva-Makulec Krassimira
Published: December 2023

Soil fauna, including terrestrial isopods, millipedes and earthworms, play an important role in the decomposition of litter through the process of shredding it during consumption. In the present study, the food preferences in two detritivores, the common woodlouse (Oniscus asellus) and the earthworm (Lumbricus rubellus) over the leaf litter of four common tree species: common black alder (Alnus glutinosa), silver birch (Betula pendula), small-leaved linden (Tilia cordata) and pedunculate oak (Quercus robur) were quantified in the laboratory. For each animal species, two sets of feeding mesocosms were prepared: one set with single litter species and another with mixed litter material (cafeteria-type test), where the animals were allowed to choose among the four litter species at once. The food preferences of the studied animals were determined on the basis of the consumption (mass loss) of litter for each litter species at the end of two-weeks lasting experiments. The results showed that the litter mass losses in both detritivores were significantly influenced by the tree species. The litter mass losses can be ranked in descending order as follows: alder, birch, linden, oak. In the case of O. asellus, litter mixing had no effect on litter mass loss when compared to single alder and birch litter, however mixing clearly accelerated litter mass loss compared to single lime or oak litter. For L. rubellus, litter mixing was found to slow litter mass loss compared to each single alder, birch and lime litter, while accelerating litter mass loss compared to single oak litter. For the interpretation of the results, the literature data on carbon to nitrogen ratio, as well as the proportion of difficult-to-degrade polyphenols and lignins in leaves of the studied tree species were used.
Introduction to Python
Authors: Kumar Mohbey Krishna , Acharya Malika
Published: December 2023

Python is an object-oriented programming language that can support a wide
range of applications like web development, desktop applications, etc. Its general-purpose programming features make coding easy, comprehensive and readable even for
beginners.
Control Flow
Authors: Kumar Mohbey Krishna , Acharya Malika
Published: December 2023

It's now the time for the readers to acquaint themselves with the control flow
in the programming. So far the users have seen the linear path of execution, where the
execution commences from the top and moves sequentially to the bottom. Further, our
world is filled with tasks required to run in loops, for example in banking applications,
unless the user enters the correct password the system prompts the dialogue "Please
enter the correct password". In this chapter, we introduce the concept of control flow
through which the users can decide the execution path for the program and the looping
constructs to iterate through the tasks. Our key takeaways from this chapter are listed
below:

1. Understanding the decision control statements.
2. Programming with if-else ladder and its variants.
3. A hand on for, and while loop statements.
4. Understanding the control flow alterations the jump statements like break, continue
and pass.
Exception Handling
Authors: Kumar Mohbey Krishna , Acharya Malika
Published: December 2023

In this chapter, we introduce the concept of exception handling in Python.
They are used to specify the alternate sequence of actions the program needs to jump to
at the occurrence of the event. For example, if we want to print several pages from the
printer and somewhere in the middle of the job the paper gets stuck in the printer. In
such as situation we would want to jump to the function that aborts the printing and
handles this situation by instant shut down of the printer. In such events comes the
exception handling. When the program jumps to the exception handler part the current
sequence of commands is abandoned and the commands given to the exception handler
are executed. After the exception is tackled the programming returns to the point where
the marker left.
FBDD & De Novo Drug Design
Authors: Das Anwesha , Nandi Arijit , Kumari Vijeta , Alvala Mallika
Published: December 2023

Fragment-based drug or lead discovery (FBDD or FBLD) refers to as one of
the most significant approaches in the domain of current research in the pharmaceutical
industry as well as academia. It offers a number of advantages compared to the
conventional drug discovery approach, which include – 1) It needs the lesser size of
chemical databases for the development of fragments, 2) A wide spectrum of
biophysical methodologies can be utilized for the selection of the best fit fragments
against a particular receptor, and 3) It is far more simpler, feasible, and scalable in
terms of the application when compared to the classical high-throughput screening
methods, making it more popular day by day. For a fragment to become a drug
candidate, they are analyzed and evaluated on the basis of numerous strategies and
criteria, which are thoroughly explained in this chapter. One important term in the field
of FBDD is de novo drug design (DNDD), which means the design and development of
new ligand molecules or drug candidates from scratch using a wide range of in silico
approaches and algorithmic tools, among which AI-based platforms are gaining large
attraction. A principle segment of AI includes DRL that finds numerous applicabilities
in the DNDD sector, such as the discovery of novel inhibitors of BACE1 enzyme,
identification and optimization of new antagonists of DDR1 kinase enzyme, and
development and design of ligand molecules specific to target adenosine A2A, etc. In
this book chapter, several aspects of both FBDD and DNDD are briefly discussed.
Free Energy Estimation for Drug Discovery: Background and Perspectives
Authors: Prieto-Martínez Fernando D. , Galván-Ciprés Yelzyn
Published: December 2023

Drug development is a remarkably complex subject, with potency and
specificity being the desired traits in the early stages of research. Yet, these need
careful thought and rational design, which has led to the inclusion of multidisciplinary
efforts and non-chemistry methods in the ever-changing landscape of medicinal
chemistry. Computational approximation of protein-ligand interactions is the main goal
of the so-called structure-based methods. Over the years, there has been a notable
improvement in the predictive power of approaches like molecular force fields.
Mainstream applications of these include molecular docking, a well-known method for
high-throughput virtual screening. Still, even with notable success cases, the search for
accurate and efficient methods for free energy estimation remains a major goal in the
field. Recently, with the advent of technology, more exhaustive simulations are
possible in a reasonable time. Herein, we discuss free energy predictions and
applications of perturbation theory, with emphasis on their role in molecular design and
drug discovery. Our aim is to provide a concise but comprehensive view of current
trends, best practices, and overall perspectives in this maturing field of computational
chemistry.
A globalizáció hatása a felsőoktatásban, az online oktatás előnyei és hátrányai
Authors: Kézi Csaba
Published: December 2023

This article was prepared with the support of PADME (Pallas Athéné Domus Meriti). E-learning has many advantages and disadvantages. Among these, I would like to highlight some of the more important ones, as well as present the results of my surveys in which I assessed university students' modeling, abstraction and lexical knowledge before and after online education.