bluuebunny/crossref_metadata_2025 huggingface dataset:
Adjuvant hormone therapy in early-stage estrogen-positive breast cancer: a systematic review and network meta-analysis
Authors: Belousov D. Yu. , Cheberda A. E.
Published: June 2023

Relevance. Adjuvant hormonal therapy in postmenopausal women at an early-stage of estrogen-positive breast cancer (BC) includes anastrozole, letrozole, tamoxifen, toremifene, and exemestane, but the most effective drug is not known, and in this situation, the role of adjuvant hormonal therapy becomes especially debatable.

The purpose of the study. Conducting an indirect comparison of oestrogen antagonists and aromatase inhibitors used in postmenopausal women with early-stage estrogen-positive breast cancer through a systematic search and selection of transitive data from randomized controlled trials (RCTs), and their subsequent quantitative synthesis in a network meta-analysis.

Methods. We conducted a systematic review in two databases: MEDLINE and The Cochrane Central Register of Controlled Trials. Full-text versions of articles from RCTs were reviewed to evaluate the comparative efficacy of adjuvant hormonal monotherapy with toremifene, tamoxifen, anastrozole, letrozole, and exemestane in women with early-stage estrogen-positive postmenopausal breast cancer who had not previously received hormone therapy. Efficacy was assessed by overall survival (OS). A network meta-analysis was carried out using the NetMetaXL programme.

Results. As a result of a systematic search, we selected 8 RCTs involving 25167 patients. When performing a synthesis of the obtained data using a network meta-analysis, no statistically significant differences in 5-year OS were obtained between the comparators.

Conclusions. There are no clinically significant differences in 5-year OS between the compared drugs of adjuvant hormonal monotherapy in early-stage breast cancer.
Simple intratesticular cysts: literature review
Authors: Shormanov I. S. , Ryzhkov A. I. , Sokolova S. Yu.
Published: June 2023

Introduction. Until recently, simple cysts of the testicular parenchyma were considered extremely rare pathology. Recently, this condition has been diagnosed more often, which is largely due to the widespread use of ultrasound examination of the scrotum. To date, a unified approach to the management of patients with this nosology has not been developed, which served as the basis for a review of the literature on simple cysts of the testicular parenchyma.

Results. Simple cysts of the testicular parenchyma are observed in 8–10 % of patients. The etiology of simple intratesticular cysts remains unknown. Small cysts of the testicular parenchyma are most often asymptomatic, pain symptoms of a nature for large cysts larger than 2 cm. Asymptomatic single cysts of the testicular parenchyma do not require surgical treatment and probably need dynamic monitoring. In patients with symptomatic and multiple cysts, surgical treatment should be recommended. Preference should be given to organpreserving techniques in the form of cyst resection/enucleation. Orchiectomy for the treatment of simple intratesticular cysts should be considered in exceptional cases.
Masjid sebagai sarana pemberdayaan ekonomi umat
Authors: Adnanda Yudha Rhealdi  , Muthoifin  , Rizka
Published: June 2023

Community development by utilizing the mosque's financial circulation is one of the efforts to maximize the role and function of the mosque. Communities around the mosque are empowered economically through mosque activities. Al-Falah Grand Mosque is one of the mosques that has implemented economic empowerment activities for the people around the mosque. As a result, this mosque became a prosperous mosque and even became a national pilot mosque. The purpose of this research is to dissect the management strategy of Al-Falah Mosque in Sragen in empowering the people's economy. This type of research is qualitative research with a descriptive approach that utilizes case studies to analyze problems. Collecting data using interview techniques, observation and documentation. The research location is at Masjid Raya Al-Falah Sragen. This research resulted in an explanation of the strategy of the Al-Falah Mosque in Sragen in empowering the people's economy. Many kinds of activities are carried out for empowerment participants, ranging from religious studies, learning to read the Koran and tahsin qiro'ah, joint dhikr, distribution of basic necessities and other incidental training to make the Al-Falah Mosque's breadwinner community continue to grow.
HUMAN RESOURCE SCORECARD Mengaitkan Orang, Strategi dan Kinerja SDM ( Suatu Model Pengukuran Kinerja SDM)
Authors: Maradita Fendy
Published: June 2023

Dalam artikle ini membahas tentang apa itu Human Resource Scorecard. Human Resource Scorecard merupakan suatu pengukuran kinerja sumber daya manusia dalam perusahaan maupun perguruan tingg adapaun tema dalam Human Resource Scorecard yaitu dengan menentukan bagaimana perusahaan maupun perguruan tinggi memilih dan menentukan visi,misi dan juga strategi yang digunakan oleh perusahaan maupun perguruan tinggi. Sumber Daya Manusia yang merupakan asset dalam perusahaan perlu dilakukan bagaimana kinerjanya dalam perusahaan dengan mengetahui kinerja sumber daya manusia maka bisa juga perusahaan ataupun perguruan tinggi bisa melihat kinerja perusahaan jadi walaupun tanpa melihat dari segi finansial maka kinerja perusahaan bisa jua di ukur dengan suatu model yang dikembangkan melalui Balanced Scorecard. Didalam article ini juga terdapat tahapan-tahapan dalam menentukan dan mengimplementasikan Human Resourced Scorecard. Karena masih dalam perkembangan dan juga turunan dari Balanced Scorecard maka masih beberapa penelitian yang menggunakan model ini dalam penelitiannya dan beberapa perusahaan yang menggunakan model ini dalam mengukur kinerja SDM dalam perusahaannya maupun perguruan tingginya.
Preparación de madres primerizas para el cuidado efectivo del recién nacido: Una perspectiva sobre conocimientos, habilidades y actitudes
Authors: Reascos Paredes Yu Ling , Hidrobo Guzmán José Fabián , Bermeo-Córdova Bélgica , Andrade Hernández Eugenia Eliza
Published: June 2023

Introducción: El cuidado y supervivencia de los recién nacidos es responsabilidad prioritaria de toda madre, su efectividad depende principalmente de una adecuada atención, que permita mejorar la calidad de vida, y a la vez, incidir en la disminución de la mortalidad infantil. Objetivo: Evaluar los conocimientos, habilidades y actitudes de las madres primerizas en el cuidado del recién nacido. Métodos: Estudio descriptivo y narrativo de corte transversal, con enfoque multimodal; se considera para el análisis cuantitativo la información recolectada, a través de una encuesta aplicada, a 299 madres primigestas en el puerperio inmediato, atendidas en el primer trimestre del año 2022 en el Hospital cantonal de Otavalo de la provincia de Imbabura – Ecuador; el análisis cualitativo se fundamenta en versiones receptadas por medio de una entrevista estructurada a profundidad a 30 madres del mismo grupo de estudio. Resultados: El 89% de las madres investigadas son primigestas adolescentes y adultas menores a 24 años, el 56% son de etnia mestiza y el 44% son indígenas con acceso y atención intercultural; más de la mitad de la población se encuentran en unión libre, con un 70% de instrucción secundaria y apenas el 10% cursando educación superior. Las madres primerizas presentan temor y miedo por las confusiones y vacíos sobre el conocimiento y actitudes de los cuidados del recién nacido, la lactancia materna exclusiva, técnicas de amamantamiento, posiciones adecuadas para realizar el baño, cuidados del cordón umbilical, posición del niño al dormir, signos de alarma, controles preventivos de salud y vacunación para evitar enfermedades. Conclusiones: El conocimiento sobre el cuidado del recién nacido influye en las habilidades y actitudes que las mujeres primigestas adoptan para la atención del niño, se evidencia falta de educación y preparación durante la atención prenatal.
Caminando con las Tripas entre las manos (Chunchulniypas Qapirisqam Purirani) Impacto de las Esterilizaciones Forzadas
Authors: Rojas Orellana Félix , Cáceres Quenta Rolando , Zúñiga Vásquez María Emma , Maquera Maquera Yuselino
Published: June 2023

Objetivo: Describir y mostrar evidencia la problemática de las esterilizaciones forzadas en las mujeres indígenas quechuas en contexto de violencia política en la región Ayacucho. La informante clave describe, que en realidad simbólicamente le habían cortado las tetas y seccionando el útero para que no tengan más hijos. Metodología. La metodología fue cualitativa, diseño descriptivo, la técnica estudio de caso de una mujer esterilizada de manera interpretativo y explicativo con fuentes primarias y secundarias. Resultado. Lo han cortado la barriga para sacar el aparato reproductor de manera obligatoria e involuntaria, estas desde una política de planificación familiar. Sin embargo, por una mala sutura del corte, se infectó y se hizo crónica la herida afectada y reventó expulsado una parte de los intestinos de la mujer, así tuvo que caminar literalmente con las tripas cargadas entre las manos por no tener recursos para su tratamiento por un espacio de 4 años. Conclusiones. El hecho social, radica de que la esterilización forzada, obedeció a una política de un plan demográfico y esta se relaciona con el contexto de violencia política entre los años de 1980 al 2000 en la región Ayacucho (Perú).
Educación formal y su relación con el ejercicio político. una aproximación interpretativa desde la sociología de la educación
Authors: Nombre* José Andrés Herrera Rey
Published: June 2023

El objetivo fundamental de este artículo reside en aportar elementos epistemológicos desde la sociología de la educación, que permitan una aproximación interpretativa al fenómeno de la educación formal que reciben los discentes del ciclo diversificado de la educación costarricense y su conexión desde la praxis, con el ejercicio político ciudadano. Se plantean elementos teóricos y metodológicos propios de la sociología que posibilitan analizar e interpretar el tipo de formación en materia ciudadana que les es provisto a los discentes, desde el ámbito formal de la educación pública y su impacto en la corresponsabilidad y participación ciudadana que tienen las personas. Se toma como punto referencial de análisis, los contenidos y acciones programáticas que se gestan desde la asignatura Educación Cívica, ya que se considera que por aspectos de orden etario y de madurez en los estudiantes, permite abordar con mayor propiedad las acciones o inacciones en el ejercicio político ciudadano que manifiestan estas personas. Se parte del supuesto de que la educación formal ciudadana que se brinda desde la formalidad se limita únicamente a cubrir aspectos formales y procedimentales, que pretenden en forma clara, perpetuar y legitimar el status quo, en detrimento de la formación integral ciudadana que permita a los discentes forjar un pensamiento crítico que posibilite un ejercicio político ciudadano de mayor y mejor calidad.
Intervención Educativa “Fortaleza” en el conocimiento de la prevención del embarazo en adolescentes en un Hospital Público de Lima- 2022
Authors: Vélez-Gallardo María Del Carmen , Aliaga-Pacora Alicia Agromelis
Published: June 2023

El objetivo de la investigación fue determinar la eficacia del programa de intervención educativa “Fortaleza” en el conocimiento de la prevención del embarazo en adolescentes en un hospital público de Lima- 2022. Para la Organización Panamericana de la Salud (2017), la educación sexual debe impartirse en forma integral y de manera sistemática a través de la educación en los diferentes niveles y modalidades en las instituciones educativas. A fin de desarrollar una sexualidad saludable considerada como Derecho Humano. Que importante es que las diversas instituciones como el Ministerio de Educación, de Salud entre otros planteen como políticas de Estado programas de prevención de embarazo en adolescentes, así como de otras enfermedades de alto riesgo, con la finalidad de que la población tome consciencia de la importancia de su desarrollo físico y la calidad de vida que debe mantener. La presente investigación fue de carácter experimental, se aplicó los niveles descriptivo y experimental con un diseño pre experimental antes y después. La muestra estuvo constituida por 30 madres adolescentes que asistían a un hospital público de Lima. Quedando demostrada la hipótesis, en la que los resultados evidenciaron una diferencia de medias el pretest = 10,867 y el Postest = 15,900, dando como diferencia = 5,033. Lo que significa que el programa de intervención educativa “Fortaleza” fue eficaz. El programa tuvo una duración de 12 sesiones. Se recomienda seguir con este tipo de intervenciones a fin de mejorar el normal desarrollo de los adolescentes.
Detection of Intestinal Parasites in Domestic Cats in Mosul City, Iraq
Authors: Najm Nagham , Khalaf Waad , Mekhael Yousif Raed
Published: June 2023

Gastrointestinal parasites are a major source of disease in cats in the tropics and are a major cause of public health problems in many parts of the world. This study was conducted to investigate the intestinal parasites of domestic cats and infection rates according to the age of the animal. Fifty fecal samples were collected from domestic cats in Mosul city during the period from October 2019 Until the end of January 2020. Eleven species of intestinal parasite were identified in the feces of domestic cats included three genera of Nematodes: Toxocara cati (16%), Toxascaris leonina (8%), Ancylostoma tubaeforme (8%), two genera of Cestodes: Taenia caniforms (4%), Diphylobothrium latum (2%), one genus of the Trematodes: Schistosoma intercalatum (2%) and five species of intestinal protozoa: Isospora felis (32%), Isospora rivolta (28%), Cryptosporidium spp. (10%), Entamoeba coli (12%), Toxoplasma like oocyst (6%). The total infection with intestinal parasites was (64%). The highest rate of infection was Isospora felis (32%), followed by Isospora rivolta (28%). This is the first record of the Isospora genus in the Mosul city, also recorded in this study for the first time in Iraq, the infection of cats with the parasite Schistosoma intercalatum (2%) and the infection with Entamoeba coli (12%) is the first record in the Mosul city. No significant differences were observed in the infection rates with different parasites between the age groups of animals and between the types of infection with different species of intestinal parasites in domestic cats.
Diagnosis of Pregnancy and Uterine Infections by Ultrasound During out Breeding in Saanen Goats in Halabja Province, Kurdistan, Iraq
Authors: Ghaidan Talib
Published: June 2023

The aim of this study is to find out the incidence of pregnancy and some uterine diseases, such as hydrometra and mucometra in female Saanen goats out of seasonal breeding by using ultrasound scanning. This study was conducted in January 2022 in field of Saanen goats in Halabja province / Kurdistan Region. Out of 120 examination of female Saanen goats, the investigation were recorded 8 (6.7%) for pregnant, 80 (66.7%) non pregnant and 2 (1.6%) abortion whereas 18 (15%) and 12 (10%) for hydrometra and mucometra respectively. The previous conditions of infected uterus are considered a pseudopregnancy in goats according to the many researchers. In addition to these uterine infections are causes temporary infertility in goats.Therefore, it is preferable to treat such cases as soon as possible using hormones such as PGF2α. Finally it concluded that real-time ultrasound is considered rapid, precise, and accuracy device used for diagnosis of pregnancy and reproductive disorders represented by hydrometra and mucometra in goats.
Effect of N-Acetyl Cysteine, Selenium and Zinc as Oral Nutritional Supplement on Reproductive Performance in Local Iraqi Ewes.
Authors: Huwaish M. H. , Mohammed T. R.
Published: June 2023

The study aimed to investigate the effect of the administration N-acytl cysteine to ewes with or without selenium and zinc on reproductive performance and the level of estrogen and progesterone hormones for local ewes. 24 local ewes were used, 3-5 of age and weighing 45-55 kg. They were randomly distributed to 4 groups, 6 ewes for each one. All ewes were treated six days before pushing the vaginal sponges and continued for 45 days. The Group 1 (T1) was treated with (10 mg N-acytl cysteine/kg body weight), Group 2 (T2) was treated with (10 mg N-acytl cysteine/kg body weight + 0.03 mg selenium/kg body weight), Group 3 (T3) was treated with (10 mg N-acytl cysteine/ kg of body weight + 0.03 mg zinc/kg of body weight) while the Group 4 (T4) was left without treatment (control group). The results showed a significant increased (p≤0.05) of treatment (T1) at the time of first estrus, followed by the control treatment, then treatment (T2, T3). Results recorded a significant increased (p≤0.05) of T1, T3 and T2 respectively in estrus rate. Furthermore, the treated group showed a significant increased (p≤0.05) compared with the control group in the fertilization %pregnancy, the percentage of twins, births and the number of births. The supplement N-acetyl cysteine with selenium or zinc led to an improvement in reproductive performance
Protective Effect of Acetyl L-Carnitine on Rat Spermatogenesis Defects Induced by Lead Acetate
Authors: Ibrahim Abd UL-Rahman Muhammed , Husain. Enas Osama
Published: June 2023

In this study the influences of the ameliorative effects of Acetyl-L-carnitine, when exposed to lead acetate on functional aspects in spermatogenesis process in the testes of albino male rats, studied, 24 male albino rats weight 178-250 g were randomly distributed into four groups, 6 rats in each, the control group received distilled water orally, Treatment 1 lead acetate group received 10mgkg body weight orally, Treatment 2 acetyl L-carnitine(ALCAR) group received 100mgkg body weight orally, and Treatment 3 lead acetate and acetyl L-carnitine group received 10mgkg body weight and 100mgkg body weight orally respectively. After the end of the experiment the weight of sexual organs were taken, in addition, the total sperm count number, and percentage of dead, live, with abnormal spermatozoa also have been calculated. Results showed that the total sperm count in the lead acetate group was decreased compared with the control and ALCAR groups. The lead acetate with ALCAR showed an increase in total sperm count and live sperm percentage in comparison with control and ALCAR groups. Dead and abnormal sperm percentage increased in the lead acetate group and in lead with ALCAR groups in compared with control and ALCAR grou
PENGEMBANGAN DESAIN PEMBELAJARAN BAHASA INGGRIS MENGGUNAKAN DIRECT METHOD BERBASIS BUDAYA LOKAL UNTUK SISWA SEKOLAH DASAR
Authors: Edo Fatima claudian , Noge Maria Desidaria , Awe Ermelinda Yosefa
Published: June 2023

Abstrak Penelitian ini bertujuan untuk : (1) untuk menghasilkan desain pembelajaran bahasa Inggris menggunakan direct method berbasis budaya lokal untuk sekolah dasar, (2) untuk mengetahui kualitas hasil uji produk pengembangan desain pembelajaran bahasa Inggris menggunakan direct method berbasis budaya lokal untuk sekolah dasar. Subjek uji coba dalam penelitian ini antara lain guru bahasa Inggris sebagai ahli konten/materi dari guru SMPS Katolik Kartini Mataloko dan guru SMPS Soegijapranata Mataloko, dosen Universitas Nusantara PGRI Kediri sebagai ahli desain pembelajaran dan 6 orang guru SD sebagai pengguna produk. Desain pembelajaran bahasa Inggris berbasis budaya lokal ini dikembangkan menggunakan model ADDIE terdiri atas lima langkah, yaitu: (1) analyze, (2) design, (3) development, (4) implementation, dan (5) evaluation. Hasil uji coba pada ahli konten/materi mendapat nilai (4,6) dan masuk dalam kategori sangat baik, dan mendapat nilai (3,7) dan masuk dalam kategori baik. Hasil uji coba pada ahli desain pembelajaran mendapat nilai (4) serta masuk dalam kategori baik. Hasil uji coba pada calon pengguna produk SDI Bobou mendapat nilai (4,2), (4,1), dan (4,2) serta masuk dalam kategori sangat baik, SDI Lebijaga mendapat nilai (4,2), (4), dan (4,1) serta masuk dalam kategori sangat baik dan baik. Berdasarkan hasil uji coba tersebut maka pengembangan desain pembelajaran bahasa Inggris menggunakan direct method berbasis budaya lokal Ngada untuk siswa sekolah dasar yang telah dirancang ini dapat diberikan dan digunakan.
Perceptions of pre-service teachers on breakout room micro-teaching with Zoom
Authors: Buttler Timothy , Scheurer Jacob
Published: June 2023

Due to the emergence of Covid-19, many educators moved from a face-to-face teaching environment to an online microteaching setting using Zoom. This study explores pre-service teachers’ perspectives on microteaching within Zoom’s breakout rooms. The authors approached this study from a positivist-postpositivist perspective employing a mixed-methods methodology. The exploratory sequential mixed-method design employed here combines qualitative and quantitative data. Analysis entailed open coding of data from Zoom recordings and statistical analysis of a post-course survey. Convenience sampling of pre-service teachers (PSTs) from a teacher education teaching method course provided the data sets. Findings indicate that microteaching activities within breakout rooms facilitated an environment where pre-service teachers engaged and conversed with peers while developing teaching skills. PSTs valued breakout room interactions, though males and females valued different aspects. Finally, although the findings suggest that microteaching in Zoom’s breakout rooms is effective, the findings indicate that the pre-service teachers desired a return to the classroom. This research extends previous research on online microteaching student experiences by providing recommendations regarding microteaching via video conferences.
Using WhatsAppbased mobile learning environments during abrupt switches to online learning: A duoethnographic account
Authors: Van Staden Christa , Nel Liezel
Published: June 2023

Abrupt switches to online learning without face-to-face contact between facilitators and students can cause distress and have a negative impact on student success. As students use instant messaging applications (IMAs) to communicate with one another, we have integrated WhatsApp-based mobile learning environments (MLEs) in two disparate higher education settings to facilitate learning. Christa used an MLE pre-pandemic in a postgraduate distance education context, while Liezel used several MLEs during the pandemic in an undergraduate contact education context. In this duoethnographic1 account, we share our stories about using these MLEs during times of distress. Duoethnography is a collaborative methodology that allowed us to juxtapose our life histories to create multiple understandings of the phenomenon to learn from one another. With currere as theoretical framework, we employed storytelling to compare our life histories, educational contexts and beliefs while we illustrate a sense of personal change. In addition to sharing our insights regarding the affordances and challenges related to WhatsApp-based MLEs, we illustrate how this dialogic methodology facilitated dialogue and reflection – affording two educational researchers in disparate higher education contexts deeper insights regarding their own practices.
Implementation Of Digital Marketing as An Effort to Increase Sales for MSMEs In the City of Bandar Lampung in The New Normal
Authors: SAEPUDIN Saepudin , AZKA Fuad , YUNIFER Muhammad Glenn
Published: June 2023

Purpose:Since the World Health Organization (WHO implemented the Coronavirus as a global pandemic, with case data in Indonesia as of June 29, 2020, with the number of confirmed cases reaching 55,092 people, it had a major impact on various sectors, one of which is the economic sector, especially MSME businesses. This study aims to see the role of digital marketing in increasing MSME sales in Bandar Lampung City during the COVID-19 pandemic.Methodology:This study uses a qualitative method called literature study, namely the technique of collecting data and information through various literature or references. The primary references used in scientific writing are scientific journals, information, and national and international news. The data used are secondary data, which are mostly obtained from websites and government statistics that are relevant to the object being studied. Processing of the data and information contained in this scientific paper using the descriptive methodFindings:In this scientific paper, digital marketing strategies will be explained with the concepts of social media marketing and content marketing. Digital marketing provides several benefits, including connecting sellers and buyers on the internet, expanding market share, and generating higher sales.Implication:By implementing digital marketing as a marketing strategy, sales turnover for MSME players will increase.
The Neotropical antlion genus Ameromyia Banks, 1913 (Neuroptera: Myrmeleontidae), systematics and redefinition under a phylogenetic approach
Authors: Tavares Leon Gustavo de Miranda , Machado Renato Jose Pires , Calor Adolfo Ricardo
Published: June 2023

A taxonomic revision and the first phylogenetic hypothesis of the Neotropical genus Ameromyia Banks (Myrmeleontidae: Brachynemurini) is herein presented. The phylogeny is based on 45 morphological characters and recovered the traditional Ameromyia as paraphyletic in respect to the monotypic genus Venezueleon Stange, which is here synonymized under Ameromyia. Three species are synonymized (A. hirsuta Navás and A. stevensi Navás under A. nigriventris (Walker), and A. pentheri Navás under A. strigosa (Banks)) and two new species are described (A. clepsydrasp. nov. and A. explicatasp. nov.). Ameromyia sensu novo is a valid genus with 12 species restricted to South America, and divided into two species groups. Taxonomic keys are also presented to adults and larvae, as well as a discussion on the genus biology.
Capital or Democracy? A Review of Thomas Piketty's Capitalism and Ideology
Authors: Rustin Michael
Published: June 2023

Thomas Piketty's Capitalism and Ideology is the 1150-page 2020 sequel to Capital in the Twentieth Century, a best-selling publishing sensation in 2014 that described the inexorable growth of inequality under capitalism. Capitalism and Ideology develops the thesis of the earlier
volume into a micro-historical account of the development of property-based societies. It proposes a strong programme for their reform in the direction of a renewed social democracy. In offering an historical account of the development of capitalism it enables us to reopen debates about political
futures, and to locate proposals for change within this trajectory: it historicises the present as a way of arguing that things could be otherwise. Possibly because of its explicitly socialist political argument, it has not so far received the attention and acclaim of its predecessor.
Neutropenia: A Brief Review
Authors: Villarreal Mariela
Published: June 2023

Neutropenia is one of the most common abnormalities on complete blood count encountered in pediatric clinical practice. It causes anxiety in the pediatric clinician as well as in the patient and their family. Neutropenia can be inherited or acquired. Acquired neutropenia is much more common than inherited neutropenia. Acquired neutropenia self-resolves after the offending cause is removed, and therefore, most acquired neutropenia can be managed by primary care physicians, unless they are associated with severe infections. In contrast, inherited neutropenia needs to be managed in collaboration with the hematologist.

[
Pediatr Ann
. 2023;52(6):e238–e241.]
Social Learning in Disadvantaged Municipalities in Hungary
Authors: Lipták Katalin
Published: June 2023

The aim of the study is to measure the human resource potential of the North-Hungarian region in Hungary by developing and estimating a human development index at the level of municipalities. The results of the calculations will be produced for the last 3 census years (1990, 2001, 2011), showing which municipalities have the strongest human resource potential. In disadvantaged municipalities with low human development, there is an increased need for a social learning process. The existence of social enterprises can further strengthen the population retention capacity of a municipality, especially when targeted improvements and innovations are created. The study describes a successful social enterprise in a deprived municipality.
Comprehensive Evaluation of Experimental Teaching Quality Using AHP-TOPSIS Technique
Authors: Wang Yongqi
Published: June 2023

The key of university experimental teaching is to help students gradually perfect from knowledge learning to improvement of actual operational ability through experiments in the teaching and learning process. University experimental teaching is conducive for promoting innovative thinking and ability of practice of university students, and it plays an important role in the entire talent training system. Establishing scientific and reasonable evaluation methods and reflecting shortages in practical experimental teaching are not only keys of evaluation but also important guarantee to improve university experimental teaching quality. In this study, an evaluation index system of experimental teaching quality was constructed by combining analytic hierarchy process (AHP) and technique for order preference by similarity to ideal solution (TOPSIS). Weights of indexes were determined. Moreover, a case study based on a comprehensive evaluation of experimental teaching quality of Construction Engineering CAD for civil engineering majors of undergraduates was performed. Results demonstrated that Level 2 indexes about teachers’ good preparation of lessons and complete and standard teaching documents (X-1-3), as well as students’ active thinking and positive participation in classroom learning (X-3-2), had the highest weight. Students’ evaluation ranking results provided quantitative references to more scientific evaluation of experimental teaching. The comprehensive evaluation of experimental teaching quality using AHP-TOPSIS technique solves the mutual dependence and feedback relationship among evaluation indexes effectively, and avoids influences of subjectivity and one-sidedness of artificial weighting. Research conclusions can provide important references to optimize experimental teaching process, train the innovation ability of students, increase the comprehensive quality of students, and deepen reform in experimental teaching.
Mobile and Web-Based Security Guard Patrolling, Monitoring and Reporting System to Maintain Safe and Secure Environment at Premises
Authors: Gannapathy Vigneswara Rao , Narayanamurthy Vigneswaran , Subramaniam Siva Kumar , Bin Tuani Ibrahim Ahamed Fayeez , Md Isa Ida Syafiza , Rajkumar Sujatha
Published: June 2023

The guard tour system helps companies and organizations to monitor their security activities such as protecting people, buildings, assets, or equipment. According to the existing system, the patrolling at each checkpoint is being executed by using RFID-based digital data loggers that records and save all patrolling entries internally. The data will be transferred manually by the guard once the patrolling is completed. In some cases, when there is a problem with the device, the system unable to retrieve the patrolling data that has been already stored in the device. In addition, the current system also not be able to track the guard’s movement, patrolling information, and incidents in real-time basis. The developed Security Guard Patrolling, Monitoring and Reporting (eSmartGuard) system is able incorporates many unique and intelligent technologies such as NFC, GPS and IoT to records and save the patrolling data automatically on the cloud/server in real-time basis. An important value-added feature of the system is real-time incidents notification that able to notify any risk of the guards instantly to the in-charged security officer. Furthermore, through the eSmartGuard, the patrolling information such as time, date, GPS coordinate, guard ID can be monitored and retrieved remotely via proposed Mobile Apps and Web at a convenient time. The eSmartGuard patrolling system is proposed to improve the safety of the people and assets by assisting the security guards to perform their patrolling duty efficiently.
A Comparative Study for SDN Security Based on Machine Learning
Authors: Khattab M. Ali Alheeti  , Abdulkareem Alzahrani  , Maha Alamri  , Aythem Khairi Kareem  , Duaa Al_Dosary
Published: June 2023

In the past decade, traditional networks have been utilized to transfer data between more than one node. The primary problem related to formal networks is their stable essence, which makes them incapable of meeting the requirements of nodes recently inserted into the network. Thus, formal networks are substituted by a Software Defined Network (SDN). The latter can be utilized to construct a structure for intensive data applications like big data. In this paper, a comparative investigation of Deep Neural Network (DNN) and Machine Learning (ML) techniques that uses various feature selection techniques is undertaken. The ML techniques employed in this approach are decision tree (DT), Naïve Bayes (NB), Support Vector Machine (SVM). The proposed approach is tested experimentally and evaluated using an available NSL–KDD dataset. This dataset includes 41 features and 148,517 samples. To evaluate the techniques, several estimation measurements are calculated. The results prove that DT is the most accurate and effective approach. Furthermore, the evaluation measurements indicate the efficacy of the presented approach compared to earlier studies.
Recent and Emerging Technologies in Industrial IoT
Authors: Nair Rekha R. , Babu Tina , S. Kishore
Published: June 2023

The industrial internet of things (IIoT) is evolving through remote monitoring, cognitive analytics, and industrial process control. Through product customization, intelligent monitoring applications for production floor shops and machine health, and predictive and preventive maintenance of industrial equipment, the primary goal of IIoT is to achieve high operational efficiency, increased productivity, and better management of industrial assets and processes. But because the industrial sector is only now beginning to implement full-stack development solutions with IIoT, there is a need to deal with the problems that are emerging. The IIoT keeps industrial equipment, machines, and cloud-based applications connected. The authors emphasize the advantages of IIoT, which is one of the chapter's three key themes, which include emerging IIoT hardware and software technologies followed by the challenges of IIoT. Further, this chapter focuses on recent trends and technologies in industrial IoT and challenges in IIoT.
Applicability of Lipid Ratios in the Prediction of Atherogenic Risks of Women on Combined Oral Contraceptives in North-Central Nigeria
Authors: Jimoh Olanrewaju Saheed , Jimoh -Abdulghaffaar Hidaayah Oluwamayowa , Bakare Tola Yinka , Popoola Gbenga Omotade , Oladosu Waliu Olatunbosun , Grillo Elizabeth Oluwakemi , Ahmed Abdullahi , Adeniran Abiodun S.
Published: June 2023

Background:

Combined Oral Contraceptive (COC) pill is associated with atherogenic and cardiovascular changes. Some service providers use individual lipid parameters to assess these changes unlike objective calculation using standard formulae.

Objective:

To determine and compare the atherogenic changes in women on COCs using six lipid ratios; coronary heart disease risk ratio, atherogenic index of plasma, atherogenic co-efficient, Cholesterol index, Castelli risk index I, and Castelli risk index II.

Materials and Methods:

A prospective, comparative study among new acceptors of contraceptives at four family planning clinics in Ilorin, North-Central Nigeria. Participants were categorized into COCs acceptors (group I, n=120) and acceptors of non-hormonal contraceptives (group II, n=120). Participants were followed up with serial lipid profiles at 0, 3 and 6 months after uptake. Atherogenic risks were calculated using six standard formulae; statistical analysis was with SPSS version 21.0 and Analysis of variance (ANOVA) was used to compare the differences of more than two means, Bonferroni Post Hoc test was used to test for specific significance within the group and p-value <0.05 was considered significant.

Results:

A total of 225 participants (111 COC users, 114 non-COC users) aged 19 to 48 years completed the study. Serum levels of Low-Density Lipoprotein showed a statistically significant rise among the COC users over the study period (p=0.038), especially between the third and sixth months. The lipid ratios were statistically increased using all six methods despite apparently normal lipid parameters.

Conclusion:

Atherogenic changes may occur in the presence of apparently normal lipid parameters among COC users; therefore, serial lipid ratio using standard method formulae is recommended.
Cytokine Profile of Scrub Typhus Patients during the Acute Phase of Illness
Authors: Shuaib Afaf , Sultan Asfia , Azam Mohd , Rizvi Meher , Khan Fatima , Khan Haris M. , Shahid Mohd
Published: June 2023

Background:

An early and effective immune response has a role in disease presentation and clearance of pathogen. Chemokine and cytokine responses in the immunopathogenesis of scrub typhus (ST) are the least explored aspect. This study aimed to analyze interleukin (IL)-2, IL-6, tumor necrosis factor-alpha (TNF-α), IL-10, transforming growth factor (TGF)-β, and human macrophage inflammatory protein-1 (HMIP-1) β cytokine levels in ST-positive patients during the acute phase of illness.

Materials and Methods:

A total of 112 ST-positive patients were included in the study with 30 healthy controls (HC). Diagnosis was confirmed by immunoglobulin M enzyme-linked immunosorbent assay (ELISA) and indirect immunofluorescence assay. The serum levels of cytokines were measured using the ELISA. Statistical analysis was performed with the IBM SPSS Statistics 20 and MedCalc 16.1 Software.

Results:

The mean level of IL-6, IL-10, TNF-α, and HMIP1-β (72 pg/ml, 86.7 pg/ml, 187.05 pg/ml, and 12.23 pg/ml vs. 7.30 pg. ml, 8.73 pg/ml, 56.62 pg/ml, and 6.94 pg/ml, respectively) was significantly raised among the ST patients compared to the control group (P < 0.001) However, the mean and median levels of IL-2 and TGF-β were not differed significantly between ST patients and HC (P = 0.0207 and 0.0386, respectively). The severity of the disease involved respiratory complications. Around 90.1% (101/112) of patients showed high levels of IL-6, whereas IL-10, TNF-α, and HMIP-1 β levels were raised in 97 (86.6%), 63 (56.2%), and 69 (61.6%) cases, respectively. There was a higher TNF-α level in severe cases with a few values up to 298.77 pg/ml.

Conclusion:

Proinflammatory cytokines and IL-10 were found to be increased in ST patients during the acute phase of infection. A proper balance of these cytokines is required for a better outcome. These findings suggest that the status of TNF-α levels in the acute phase may predict the severity of ST disease.
Comparative Study to Correlate Hematological Parameters with the Severity of Birth Asphyxia
Authors: Mamatha R. , Meena Jeetam Singh , Sulaniya Pawan Kumar , Sehra Ram Narain , Verma Suniti
Published: June 2023

Introduction:

Birth asphyxia can alter biophysical characteristics of erythrocytes, leukocytes and platelets. Nucleated red blood cell (NRBC) in the umbilical venous blood of neonates has been reported as a possible marker of perinatal asphyxia. NRBCs, platelet count, total leukocyte count, hemoglobin, and hematocrit were taken as hematological parameters. The purpose of this study was to evaluate the various hematological changes following birth asphyxia and their correlation with the severity of birth asphyxia and its outcome.

Materials and Methods:

It was hospital-based comparative observation study conducted in neonatal units of a tertiary hospital in the northern part of India from May 2019 to May 2020. All term appropriate for gestational age newborns with birth asphyxia were taken as cases and healthy newborns as controls. The sample size of 80 participants in each group was calculated. 2 ml cord blood sample was taken for parameters used in the study. P < 0.05 was taken as statistically significant.

Results:

There was no statistically significant difference in relation to sex distribution, birth weight, parity of mothers, and mode of delivery between cases and controls. NRBC and total leukocyte count were statistically positively correlated with the severity of hypoxic-ischemic encephalopathy (HIE), whereas hemoglobin, hematocrit, and platelet counts were not statistically significant. Area under the Receiver operating characteristic (ROC) curve of NRBC was 0.812, and the NRBC count cutoff of >20 has a sensitivity of 83% and specificity of 72%. Forty-six percent of total cases with NRBC 20 or more died.

Conclusions:

NRBC has a significant positive correlation with the severity of HIE and a negative with the Apgar score. NRBCs value more than or equal to 20 can be used as a prognostic marker for assessing the severity and outcome of birth asphyxia.
Use of Diffusion Tensor Imaging in Distinguishing Neoplastic and Infective Intra-Axial Brain Lesions: An Intergroup and Etiology Wise Inter Sub-Group Analysis - Experience from a Tertiary Health Care Center in Northern India
Authors: Kumar Sukriti , Yadav Krishna , Kohli Neera , Gutch Manish , Kumar Neeraj , Bajaj Ankur , Parihar Anit
Published: June 2023

Background:

Neoplastic and infective brain lesions may present as imaging mimickers. This study aims to help differentiate between etiology of lesions based on diffusion tensor imaging (quantitatively and qualitatively).

Method:

DTI was performed in 50 patients (12 - metastases,13 - high grade glioma,13 - tuberculoma, 12 - Neurocysticercosis). Lesional and perilesional Fractional anisotropy (FA) and mean diffusivity (MD) values were calculated. Lesional and perilesional mean FA and MD values were compared by using Student’s ‘t’-test.

Result:

Mean FA values in the perilesional area of neoplastic lesions were found to be significantly higher (0.17±0.12 vs. 0.08±0.02), P < 0.001) in comparison to infective lesions. Mean MD values in the perilesional area of infective lesions were found to be significantly higher (1.51±0.22 vs. 1.20±0.33x10-3mm2/sec, P < 0.001) in comparison to neoplastic lesions. Perilesional FA was found to be significantly higher and perilesional ADC to be significantly lower in High Grade Gliomas (HGG) when compared with Metastasis, Tuberculomas or Neurocysticercosis. Infective group showed significantly higher prevalence of displacement of white matter tracts (60%) and the neoplastic group showed significantly higher prevalence of the disruption (40%).

Conclusion:

FA and MD values from the lesion and from perilesional region are helpful in differentiating among brain lesions. Fiber tracking along with quantitative parameters is helpful in determining type of involvement of tracts, thus helping in prognostication.
Laparoscopic Inguinal Hernia Repair in a Young Female with Associated Multiple Congenital Defects: A Rare Case
Authors: Rashid Tajamul , Husain Musharraf , Salman Syed Mohammad , Ohri Sonali , Sartaj Nikhat
Published: June 2023

Groin hernias are most common among patients presenting with hernia. Males have more predisposition mainly due to anatomy. However, females with groin hernia present with varied abdominal contents including ovaries and fallopian tubes. The worrisome feature of inguinal hernia with ovaries/fallopian tubes as content is torsion. Uncomplicated groin hernia with ovaries as content is managed with conventional laparoscopic or open hernia repair. Young females with groin hernias need to be evaluated thoroughly for features of androgen insensitivity syndrome or any underlying genetic disorder. A 12 years young female presented to our OPD with chief complaints of swelling in the right inguinal region for 6 months. Patient had not achieved menarche yet, however development milestones were found to be normal. On general physical examinations, deformities were noted in the right ear and left upper limb. On local examination, swelling of approximately 3x3 cm was noted in the right inguinal region. An ultrasonography scan of whole abdomen and pelvis which was suggestive of right inguinal hernia containing right ovary with malposition of the right kidney in the pelvis. Consequently, MRI whole abdomen with pelvis confirmed the findings of USG. Patient was taken for laparoscopic inguinal hernia repair. There was right sided indirect inguinal hernia with right ovary as content and a solid mass was also noted in the right pelvic region suggestive of right pelvic kidney. Right ovary was reduced back to the abdomen with transection of the right round ligament and the defect was closed back with interrupted 3’0 Vicryl sutures. Postoperative course was uneventful. Patient was counselled for genetic analysis to rule out any syndrome association. Uncomplicated groin hernia in young females and paediatric age groups with ovarian content can be easily managed with laparoscopic repair. Early intervention should be advised to prevent ovarian torsion and hence long term morbidity.
Universal objects of the infinite beta random matrix theory
Authors: Gorin Vadim , Kleptsyn Victor
Published: June 2023

We develop a theory of multilevel distributions of eigenvalues which complements Dyson’s threefold

\beta=1,2,4

approach corresponding to real/complex/quaternion matrices by

\beta=\infty

point. Our central objects are the G

\infty

E ensemble, which is a counterpart of the classical Gaussian Orthogonal/Unitary/Symplectic ensembles, and the Airy

_{\infty}

line ensemble, which is a collection of continuous curves serving as a scaling limit for largest eigenvalues at

\beta=\infty

. We develop two points of view on these objects. The probabilistic one treats them as partition functions of certain additive polymers collecting white noise. The integrable point of view expresses their distributions through the so-called associated Hermite polynomials and integrals of the Airy function. We also outline universal appearances of our ensembles as scaling limits.
Efectos de la aplicación de "jigsaw" sobre la adquisición de competencias en dirección de operaciones
Authors: López Vargas Cristina , Real Juan C.
Published: June 2023

El presente trabajo analiza los efectos de la aplicación de la técnica de "jigsaw", puzzle o rompecabezas de Aronson en la adquisición de competencias por parte de estudiantes universitarios. Más concretamente buscamos determinar qué competencias sistémicas, instrumentales e interpersonales se adquieren más fácilmente al implantar "jigsaw" en el proceso de enseñanza-aprendizaje. Los resultados alcanzados muestran que esta técnica de aprendizaje cooperativo facilita en mayor medida la adquisición de competencias sistémicas e instrumentales en comparación con las interpersonales. Dentro de las competencias sistémicas, la que desarrollan con más facilidad los alumnos es la denominada metareflexión; es decir, el aprendizaje progresivo por repetición. En el grupo de competencias instrumentales, destacan la interacción entre compañeros, las habilidades comunicativas del alumno, la participación, la ayuda en la resolución de conflictos entre compañeros surgidos durante la dinámica y la mejora de la instrucción directa. Finalmente, en relación a las competencias interpersonales, la más desarrollada es el sentido de la responsabilidad del alumno.