bluuebunny/crossref_metadata_2025 huggingface dataset:
Fujita type results for quasilinear parabolic inequalities with nonlocal terms
Authors: Filippucci Roberta , Ghergu Marius
Published: November 2021

In this paper we investigate the nonexistence of nonnegative solutions of parabolic inequalities of the form

   \begin{document}$ \begin{cases} &u_t \pm L_\mathcal A u\geq (K\ast u^p)u^q \quad\mbox{ in } \mathbb R^N \times \mathbb (0,\infty),\, N\geq 1,\\ &u(x,0) = u_0(x)\ge0 \,\, \text{ in } \mathbb R^N,\end{cases} \qquad (P^{\pm}) $\end{document}

where \begin{document}$ u_0\in L^1_{loc}({\mathbb R}^N) $\end{document}, \begin{document}$ L_{\mathcal{A}} $\end{document} denotes a weakly \begin{document}$ m $\end{document}-coercive operator, which includes as prototype the \begin{document}$ m $\end{document}-Laplacian or the generalized mean curvature operator, \begin{document}$ p,\,q>0 $\end{document}, while \begin{document}$ K\ast u^p $\end{document} stands for the standard convolution operator between a weight \begin{document}$ K>0 $\end{document} satisfying suitable conditions at infinity and \begin{document}$ u^p $\end{document}. For problem \begin{document}$ (P^-) $\end{document} we obtain a Fujita type exponent while for \begin{document}$ (P^+) $\end{document} we show that no such critical exponent exists. Our approach relies on nonlinear capacity estimates adapted to the nonlocal setting of our problems. No comparison results or maximum principles are required.
Happiness as an Expression of Health
Authors: de Carvalho Rodolfo Andrade , Magalhães Jorge Lima de
Published: November 2021

Health gained a global prominence and became a right declared by the World Health Organization in 1948. In the 21st century, it is understood as a complete well-being of the individual, far beyond the absence of disease. In this context, the right to happiness translates as an expression of the aspirations for the realization of the right to health. Thus, this chapter aims to understand, in the light of the Freudian perspective, the aspects of soul life that lead the individual to the exhausting task of seeking happiness and seeks to reflect the possible contributions that legal science can offer to the improvement of individual well-being as a right health in the context of global health. Freud's theories about the formation of the psychic apparatus, his conception of malaise caused by culture and legal interventions that can possibly contribute to the reduction of individual unhappiness are presented.
COVID-19 Spread Prediction Using Prophet and Data Fusion Algorithm
Authors: V. Sangeetha , D. Evangeline , M. Sinthuja
Published: November 2021

Today, technology plays a vital role in the healthcare industry. In the traditional way, physicians' minds were predicting the unknown disease based on their expertise and experience. Use of new technology like predictive analytics is transforming the healthcare industry. Predictive analytics in healthcare uses historical data (demographic information, person's past medical history and behaviors) to make predictions about the future. In this chapter, a predictive model is proposed to predict COVID-19 using prophet algorithm. A novel approach based on longitudinal data fusion approach will maintain temporal data from time to time. Sparse regularization regression uses data source and feature level to predict the spread of virus. The proposed model designed using longitudinal data fusion offers better clinical insights. Predictions will be very beneficial to government and healthcare groups to provoke suitable measures in controlling coronavirus. It is also beneficial to pharmaceutical companies to fabricate pills at a quicker rate.
Development of an Efficient Monitoring System Using Fog Computing and Machine Learning Algorithms on Healthcare 4.0
Authors: B. J. Sowmya , D. Pradeep Kumar , R. Hanumantharaju , Mundada Gautam , Kanavalli Anita , K. N. Shreenath
Published: November 2021

Disruptive innovations in data management and analytics have led to the development of patient-centric Healthcare 4.0 from the hospital-centric Healthcare 3.0. This work presents an IoT-based monitoring systems for patients with cardiovascular abnormalities. IoT-enabled wearable ECG sensor module transmits the readings in real-time to the fog nodes/mobile app for continuous analysis. Deep learning/machine learning model automatically detect and makes prediction on the rhythmic anomalies in the data. The application alerts and notifies the physician and the patient of the rhythmic variations. Real-time detection aids in the early diagnosis of the impending heart condition in the patient and helps physicians clinically to make quick therapeutic decisions. The system is evaluated on the MIT-BIH arrhythmia dataset of ECG data and achieves an overall accuracy of 95.12% in classifying cardiac arrhythmia.
An Improved Cross-Domain Sentiment Analysis Based on a Semi-Supervised Convolutional Neural Network
Authors: Lee Lap-Kei , Chui Kwok Tai , Wang Jingjing , Fung Yin-Chun , Tan Zhanhui
Published: November 2021

The dependence on Internet in our daily life is ever-growing, which provides opportunity to discover valuable and subjective information using advanced techniques such as natural language processing and artificial intelligence. In this chapter, the research focus is a convolutional neural network for three-class (positive, neutral, and negative) cross-domain sentiment analysis. The model is enhanced in two-fold. First, a similarity label method facilitates the management between the source and target domains to generate more labelled data. Second, term frequency-inverse document frequency (TF-IDF) and latent semantic indexing (LSI) are employed to compute the similarity between source and target domains. Performance evaluation is conducted using three datasets, beauty reviews, toys reviews, and phone reviews. The proposed method enhances the accuracy by 4.3-7.6% and reduces the training time by 50%. The limitations of the research work have been discussed, which serve as the rationales of future research directions.
IL-13 Controls IL-33 Activity through Modulation of ST2
Authors: Zhang Melvin , Duffen Jennifer L , Nocka Karl H , Kasaian Marion T
Published: November 2021

IL-33 is a multifunctional cytokine that mediates local inflammation upon tissue damage. IL-33 is known to act on multiple cell types including group 2 innate lymphoid cells (ILC2s), Th2 cells, and mast cells to drive production of Th2 cytokines including IL-5 and IL-13. IL-33 signaling activity through transmembrane ST2L can be inhibited by soluble ST2 (sST2), which acts as a decoy receptor. Previous findings suggested that modulation of IL-13 levels in mice lacking decoy IL-13Rα2, or mice lacking IL-13, impacted responsiveness to IL-33. In this study, we used Il13−/− mice to investigate whether IL-13 regulates IL-33 activity by modulating the transmembrane and soluble forms of ST2. In Il13−/− mice, the effects of IL-33 administration were exacerbated relative to wild type (WT). Il13−/− mice administered IL-33 i.p. had heightened splenomegaly, more immune cells in the peritoneum including an expanded ST2L+ ILC2 population, increased eosinophilia in the spleen and peritoneum, and reduced sST2 in the circulation and peritoneum. In the spleen, lung, and liver of mice given IL-33, gene expression of both isoforms of ST2 was increased in Il13−/− mice relative to WT. We confirmed fibroblasts to be an IL-13-responsive cell type that can regulate IL-33 activity through production of sST2. This study elucidates the important regulatory activity that IL-13 exerts on IL-33 through induction of IL-33 decoy receptor sST2 and through modulation of ST2L+ ILC2s.
Characteristics of circumferential vesico-vaginal fistulas: A cross-sectional and multicentric study
Authors: Kaboré Moussa , Kirakoya Brahima , Ouattara Adama , Yameogo Clotaire Alexis Marie Kiemdiba Donega , Nama Stéphanie Dominique Amida , Karsenty Gilles , Kaboré Fasnéwindé Aristide
Published: November 2021

The objective of the study was to determine the risk factors for development of circumferential fistula. We carried out a crosssectional, multicentric and analytical study over 7 years period, from 1st January, 2010 to 31 December, 2016. We compared circumferential and non- circumferential fistula patients in order to determine the risk factors for circumferential fistula development. Circumferential fistula accounted for 20% (91/456) of all vesico-vaginal fistulas. The mean age of the 456 patients was 35.9 years±12.15 (min 15 years; max 72 years). On univariate analysis, factors associated with the risk of circumferential fistula were: residence (P=0.039; OR=1.7), parity (P=0.04; OR=0.47), marital status before fistula (P=0.002; 4.3), duration of labor (P=0.041; OR=2.7) and fistula aetiology (P=0.038; OR=2.54). In a logistic regression model, two factors remained significant: marital status before fistula (P=0.029; OR=0.13) and duration of labor (P=0.017; OR=0.26). Circumferential fistula occurs in urban, primiparous, unmarried women who have been in labor for more than 41 hours.
Identification of Patients with Recurrent Epithelial Ovarian Cancer Who Will Benefit from More Than Three Lines of Chemotherapy
Authors: Seol Aeran , Yim Ga Won , Chung Joo Yeon , Kim Se Ik , Lee Maria , Kim Hee Seung , Chung Hyun Hoon , Kim Jae-Weon , Park Noh Hyun , Song Yong Sang
Published: November 2021

Purpose This study aimed to identify patients who would benefit from third and subsequent lines of chemotherapy in recurrent epithelial ovarian cancer (EOC).Materials and Methods Recurrent EOC patients who received third, fourth, or fifth-line palliative chemotherapy were retrospectively analyzed. Patients’ survival outcomes were assessed according to chemotherapy lines. Based on the best objective response, patients were divided into good-response (stable disease or better) and poor response (progressive disease or those who died before response assessment) groups. Survival outcomes were compared between the two groups, and factors associated with chemotherapy responses were investigated.Results A total of 189 patients were evaluated. Ninety-four and 95 patients were identified as good and poor response group respectively, during the study period of 2008 to 2021. The poor response group showed significantly worse progression-free survival (median, 2.1 months vs. 9.7 months; p < 0.001) and overall survival (median, 5.0 months vs. 22.9 months; p < 0.001) compared with the good response group. In multivariate analysis adjusting for clinicopathologic factors, short treatment-free interval (TFI) (hazard ratio [HR], 5.557; 95% confidence interval [CI], 2.403 to 12.850), platinum-resistant EOC (HR, 2.367; 95% CI, 1.017 to 5.510), and non-serous/endometrioid histologic type (HR, 5.045; 95% CI, 1.152 to 22.088) were identified as independent risk factors for poor response. There was no difference in serious adverse events between good and poor response groups (p=0.167).Conclusion Third and subsequent lines of chemotherapy could be carefully considered for palliative purposes in recurrent EOC patients with serous or endometrioid histology, initial platinum sensitivity, and long TFIs from the previous chemotherapy regimen.
Bleeding complications associated with the molecular adsorbent recirculating system: a retrospective study
Authors: Yoo Seon Woo , Ki Min-Jong , Kim Dal , Kim Seul Ki , Park SeungYong , Han Hyo Jin , Lee Heung Bum
Published: November 2021

Background: The molecular adsorbent recirculating system (MARS) is a hepatic replacement system that supports excretory liver function in patients with liver failure. However, since MARS has been employed in our hospital, bleeding complications have occurred in many patients during or after MARS. The objective of this study was to determine how MARS affects coagulopathy and identify specific factors associated with bleeding complications.Methods: We retrospectively analyzed data from 17 patients undergoing a total of 41 MARS sessions. Complete blood count, coagulation profiles, and blood chemistry values were compared before and after MARS. To identify pre-MARS factors associated with increased bleeding after MARS, we divided patients into bleeder and non-bleeder groups and compared their pre-MARS laboratory values.Results: MARS significantly reduced bilirubin and creatinine levels. MARS also increased prothrombin time and reduced platelet and fibrinogen, thus negatively impacting coagulation. Pre-MARS hemoglobin was significantly lower in the bleeder group than in the non-bleeder group (P=0.015). When comparing the upper and lower 33% of MARS sessions based on the hemoglobin reduction rate, hemoglobin reduction was significantly greater in MARS sessions involving patients with low pre-MARS international normalized ratio of prothrombin time (PT-INR) and factor V (P=0.038 and P=0.023, respectively).Conclusions: MARS could appears to alter coagulation-related factors such as factor V and increase the risk of bleeding complications particularly in patient with low hemoglobin. However, individual differences among patients were large, and various factors, such as low hemoglobin, PT-INR, and factor V levels, appear to be involved.
Atrial fibrillation of new onset during acute illness: prevalence of, and risk factors for, persistence after hospital discharge
Authors: Ramanathan Abarna , Pearl John Paul , Li Manshi , Wang Xiaofeng , Sadana Divyajot , Duggal Abhijit
Published: November 2021

Background: Atrial fibrillation of new onset during acute illness (AFNOAI) has a variable incidence of 1%–44% in hospitalized patients. This study assesses the risk factors for persistence of AFNOAI in the 5 years post hospital discharge for critically ill patients.Methods: This was a retrospective cohort study. All patients ≥18 years old admitted to the medical intensive care unit (MICU) of a tertiary care hospital from January 1st, 2012, to October 31st, 2015, were screened. Those designated with atrial fibrillation (AF) for the first time during the hospital admission were included. Risk factors for persistent AFNOAI were assessed using a Cox’s proportional hazards model. Results: Two-hundred and fifty-one (1.8%) of 13,983 unique MICU admissions had AFNOAI. After exclusions, 108 patients remained. Forty-one patients (38%) had persistence of AFNOAI. Age (hazard ratio [HR], 1.05; 95% confidence interval [CI], 1.01–1.08), hyperlipidemia (HR, 2.27; 95% CI, 1.02–5.05) and immunosuppression (HR, 2.29; 95% CI, 1.02–5.16) were associated with AFNOAI persistence. Diastolic dysfunction (HR, 1.46; 95% CI, 0.71–3.00) and mitral regurgitation (HR, 2.00; 95% CI, 0.91–4.37) also showed a trend towards association with AFNOAI persistence. Conclusions: Our study showed that AFNOAI has a high rate of persistence after discharge and that certain comorbid and cardiac factors may increase the risk of persistence. Anticoagulation should be considered, based on a patient’s individual AFNOAI persistence risk.
Determinants of catfish farmers’ use of sustainable environmental management practices in Enugu State, Nigeria
Authors: Andegebe Chukwuone Nnaemeka , Chiebonam Onyia Chukwuemeka , David Aniokoh Chukwuebuka
Published: November 2021

The study assessed the use of sustainable environmental management practices (SEMP) by fish farmers in Enugu state, Nigeria. Seventy-five catfish farmers selected through multistage sampling procedure were used for the study. Data were obtained with the aid of a well-structured questionnaire. Analysis of data was done using descriptive statistics, probit regression model and factor analysis. Results showed that most of the catfish farmers did not apply SEMP as only 25.33% of them had a score of 50% and above regarding the application of SEMP. The number of years spent in school and being a male significantly increased the likelihood of using SEMP. In contrast, the likelihood of use of SEMP significantly reduced with an increase in the number of production cycles carried out by a fish farmer. The fish farmers' constraints were grouped as poor technical knowledge and feed issues, financial uncertainties, and water supply problems. Government should deliver training packages and provide information on SEMP to catfish farmers through different media, including extension agents, radio and television messages, handbills and billboards. Supporting the farmers with credit facilities through existing credit programmes would help reduce their challenges in applying SEMP.
Herbaceous farmers’ linkage to grocery stores in Ondo State, Nigeria
Authors: Wole-alo Felicia Itunnu , Alokan Agnes Olubunmi
Published: November 2021

This study examined linkage between herbaceous farmers and grocery stores in Ondo State, Nigeria. A multi stage sampling procedure was used to select 96 respondents for the study. Interview schedule was used to elicit information while data were analysed using percentages, mean, and the Pearson Product Moment Correlation. The results revealed that all the respondents (100%) of the herbaceous farmers got information from input suppliers, which can enhance their linkage to grocery stores. However, the linkage between the herbaceous farmers and groceries store was low. Increase profitability ( x̅ = 4.7) and increase yield (x̅ = 4.3) were major factors that encouraged the farmers to sell to grocery stores. Result showed that farmers’ age, educational level and farm size influence farmers ‘linkage to grocery stores. There is need for the state government and other non-governmental bodies to create awareness and training for farmers on how to get connected with grocery stores other than just selling at the local markets.
Call for emergency action to limit global temperature increases, restore biodiversity, and protect health
Authors: Atwoli Lukoye , Baqui Abdullah H , Benfield Thomas , Bosurgi Raffaella , Godlee Fiona , Hancocks Stephen , Horton Richard , Laybourn- Langton Laurie , Monteiro Carlos Augusto , Norman Ian , Patrick Kirsten , Praities Nigel , Rikkert Marcel GM Olde , Rubin Eric J. , Sahni Peush , Smith Richard , Talley Nicholas J , Turale Sue , Vázquez Damián
Published: November 2021

No Abstract
Chemical profiling and anti-breast cancer potential of hexane fraction of Sphaeranthus indicus flowers
Authors: Rasheed Hafiz Majid , Wahid Fazli , Ikram Muhammad , Qaisar Muhammad , Shah Abdul Jabbar , Khan Taous
Published: November 2021

Purpose: The current study aimed to determine the phytochemicals and anti-breast cancer potential of Sphaeranthus indicus.Methods: S. indicus flowers were extracted with methanol followed by fractionation using n-hexane. For the chemical composition of n-hexane fraction, qualitative phytochemical and GC-MS analysis were performed. The anti-proliferative activity was measured by MTT assay, whereas, cytotoxic and proapoptotic effects in MCF-7 (breast cancer) cells were determined using propidium iodide, 4′,6-diamidino- 2-phenylindole, dichlorofluorescin diacetate, and JC-1 staining through fluorescent microscopy.Results: The phytochemical analysis indicated presence of phytosterols, oils and resins in the nhexane fraction. GC-MS analysis showed that n-hexane fraction comprises of 11 compounds including methyl esters of caprylic acid, myristic acid, pentadecanoic acid, palmitic acid, margaric acid, stearic acid, oleic acid, elaidic acid, linoleic acid, linolenic acid and behanic acid. The tested fraction showed remarkable cytotoxic activity against breast cancer (MCF-7) cells while it was found less toxic towards non-cancerous (BHK-21) cells. Furthermore, morphological assessment through fluorescent microscopy revealed cytotoxic and apoptotic effects by improved cell membrane permeability, increased reactive oxygen species level, compromised mitochondrial activity and condensation of chromatin network.Conclusion: The n-hexane fraction of S. indicus contains phytosterols, oils and fatty acid methyl esters and produced apoptotic effect against breast cancer cells.
Les (a)céphales dela modernité. Reconfigurations du motif de la « femme sans tȇte » dans Au Bonheur des Dames d’Émile Zola
Authors: Rachwalska von Rejchwald Jolanta
Published: November 2021

(A)céphales of modernity. Transformations of the “headless women” theme in Émile Zola’s novel Au Bonheur des Dames

The article reflects on the “headless woman” motif, taking into account its transhistorical and transsemiotic character, in Émile Zola’s novel Au Bonheur des Dames. The eleventh volume of Les Rougon- Macquart describes the moment of the transition from the economy of the “ancien regime” to capitalism. This naturalistic view of socio-economic modernity is reflected in the depiction of figures, mainly female ones. The aim of the article is to show that although the presentation of the new femininity is based on the old figure of ambivalence, this time the axis of opposition runs between the “hysterical fever of novelty” and reason or logic.
Dynamics of Language Change: The Case of Polish barzo > bardzo
Authors: Górski Rafał L.
Published: November 2021

The paper discusses the benefits and shortcomings of modelling a language change with logistic regression, an approach often called the Piotrowski-Altmann law. It is shown with an example of an isolated change, which occurred in Middle Polish, namely barzo > bardzo. The study is based on a historical corpus of Polish consisting of several hundreds of texts with over 12 million running words. Logistic regression based on the entire dataset shows relatively high goodness of fit, still there are some data points, especially close to the end of the process, which are quite far removed from the idealised trajectory. In the article, the author seeks to answer the question: to what extent the quality of the corpus affects the model. An experiment was conducted: a number of texts were randomly removed in order to create a smaller corpus, containing 90%, 75% and 50% of the texts of the entire set. Since such procedure is repeated 200 times, it is possible to compare the distribution of the scores indicating the goodness of fit of the model. It turns out that the smaller the corpus, the more diverse the goodness of fit, and in some rare cases it is even better than its counterpart for a larger corpus. Still the larger the corpus, the scores indicating goodness of fit tend to be higher.
What Are Personal Meanings of Healthy Eating and Physical Activity in Individuals Living With Spinal Cord Injury? A Qualitative Exploration
Authors: LaVela Sherri L. , Ehrlich-Jones Linda S. , Jones Kayla , Bartle Brian , Heinemann Allen W.
Published: November 2021

Objectives: To explore the personal meanings of healthy eating and physical activity among individuals living with spinal cord injury (SCI) and the information and resources they find beneficial. Methods: We conducted in-depth semistructured individual interviews to understand the personal meanings of healthy eating and physical activity among individuals with SCI. We completed a thematic analysis of qualitative data. Results: Participants were 11 Veterans and 14 civilians, predominantly male, non-Hispanic White, and with paraplegia. Data were described across two categories, including the personal meaning of healthy eating and the personal meaning of physical activity/exercise. Individuals with SCI described their meaning of healthy eating around four themes: types of food, amounts/portions of food, conscious/mindful eating, and eating to enhance health. Individuals wanted information on tailored diets for individuals with paraplegia and tetraplegia and healthy foods that are easy to prepare by people with SCI. Their personal meaning of physical activity/exercise focused on four themes: types of physical activity and exercise, staying active, moving/movement, and differences from non-SCI. Desired information around physical activity included cardiovascular workouts that are effective and possible to do in a wheelchair so that people with SCI can burn enough of the calories they consume to lose or maintain weight. Conclusion: Results provide a better understanding of what healthy eating and physical activity mean to people with SCI and information they desire toward these goals, which can be used to guide patient–provider discussions, develop health promotion programs, and tailor interventions to capitalize on meaningful concepts and beliefs that facilitate healthy behaviors.
Longitudinal Trends and Prevalence of Bowel Management in Individuals With Spinal Cord Injury
Authors: Dietz Nicholas , Sarpong Kwadwo , Ugiliweneza Beatrice , Wang Dengzhi , Aslan Sevda S. , Castillo Camilo , Boakye Maxwell , Herrity April N.
Published: November 2021

Background: Neurogenic bowel dysfunction (NBD) following spinal cord injury (SCI) represents a major source of morbidity, negatively impacting quality of life and overall independence. The long-term changes in bowel care needs are not well-reported, preventing consensus on the natural course and optimal management of NBD following injury. Objectives: To understand the changes in bowel management needs over time following SCI. Methods: A retrospective observational study using the National Spinal Cord Injury Model Systems database evaluated the degree of independence with bowel management at discharge from inpatient rehabilitation across time (1988–2016). The prevalence and consecutive trajectory of bowel management was also evaluated at discharge and at each 5-year follow-up period, for 25 years. Results: The majority of individuals discharged from inpatient rehabilitation (n = 17,492) required total assistance with bowel management, a trend that significantly increased over time. However, by 5-years post injury, there was a significant shift in bowel management needs from total assistance to modified independence. In those with consecutive 25-year follow-up data (n = 11,131), a similar shift in bowel management to a less dependent strategy occurred even at chronic time points post injury, primarily in individuals with paraplegia and classified as motor and sensory complete. Conclusion: The findings of this study highlight the need for providing continued multipronged interventions (e.g., rehabilitative, educational, psycho-social) at the different stages of SCI to support individuals not only in the immediate years after discharge but also well into the chronic stages after injury.
Fast Diameter Computation within Split Graphs
Authors: Ducoffe Guillaume , Habib Michel , Viennot Laurent
Published: November 2021

When can we compute the diameter of a graph in quasi linear time? We address
this question for the class of {\em split graphs}, that we observe to be the
hardest instances for deciding whether the diameter is at most two. We stress
that although the diameter of a non-complete split graph can only be either $2$
or $3$, under the Strong Exponential-Time Hypothesis (SETH) we cannot compute
the diameter of an $n$-vertex $m$-edge split graph in less than quadratic time
-- in the size $n+m$ of the input. Therefore it is worth to study the
complexity of diameter computation on {\em subclasses} of split graphs, in
order to better understand the complexity border. Specifically, we consider the
split graphs with bounded {\em clique-interval number} and their complements,
with the former being a natural variation of the concept of interval number for
split graphs that we introduce in this paper. We first discuss the relations
between the clique-interval number and other graph invariants such as the
classic interval number of graphs, the treewidth, the {\em VC-dimension} and
the {\em stabbing number} of a related hypergraph. Then, in part based on these
above relations, we almost completely settle the complexity of diameter
computation on these subclasses of split graphs: - For the $k$-clique-interval
split graphs, we can compute their diameter in truly subquadratic time if
$k={\cal O}(1)$, and even in quasi linear time if $k=o(\log{n})$ and in
addition a corresponding ordering of the vertices in the clique is given.
However, under SETH this cannot be done in truly subquadratic time for any $k =
\omega(\log{n})$. - For the {\em complements} of $k$-clique-interval split
graphs, we can compute their diameter in truly subquadratic time if $k={\cal
O}(1)$, and even in time ${\cal O}(km)$ if a corresponding ordering of the
vertices in the stable set is given. Again this latter result is optimal under
SETH up to polylogarithmic factors. Our findings raise the question whether a
$k$-clique interval ordering can always be computed in quasi linear time. We
prove that it is the case for $k=1$ and for some subclasses such as
bounded-treewidth split graphs, threshold graphs and comparability split
graphs. Finally, we prove that some important subclasses of split graphs --
including the ones mentioned above -- have a bounded clique-interval number.
EFFECT OF NEGATIVE SHIFT OF METALHYDRIDE CATHODE ON THE EMISSION OF H– IONS FROM PENNING DISCHARGE
Authors: Sereda I. , Tseluyko A. , Hrechko Ya.
Published: November 2021

On the basis of numerical calculations, the experimental results obtained by the authors in the study of the source of negative hydrogen ions of the Penning type with a metal hydride cathode are explained. It was shown that the yield of negative ions depends on the potential at the metal hydride cathode and is determined by the temperature of the plasma electrons. The dependence of this potential on the electron temperature is calculated numerically to ensure the maximum current of negative ions
SCINTILLATION CHARACTERISTICS OF HEAVILY DOPED CsI:Tl, IO3 CRYSTALS
Authors: Shpilinskaya A.L. , Кudin A.N. , Trefilova L.N. , Zosim D.J.
Published: November 2021

The effect of 3 IO− ions on spectrometric characteristic of CsI:Tl crystal has been considered. It has been shown that co-doping of CsI:Tl crystal by 3 IO− anions permits to obtain clear ingots with increased thallium concentration up to CTl ~ 0.9 mole % in which the concentration quenching of photo- or radioluminescence do not observed. It has been shown that the decay of solid solution in CsI:Tl, 3 IO crystals is not observed, at least up to CTl ~ 0.5 mole %, as evidenced by a good energy resolution (R = 6.3%) of samples with the specified Tl concentration and this also evidenced by a larger segregation coefficient of thallium in CsI:Tl, 3 IO crystals (k = 0.24 contrary to k = 0.19 in CsI:Tl). An explanation of thallium solid solution stability in CsI matrix has been proposed which based on experimental fact of complex formation. Compensation of elastic stresses of opposite sign due to complex formation results in preventing of nucleation for solid solution decay.
El impacto de la era digital y su importancia en los negocios educativos en tiempos de Covid-19
Authors: Reyes Denisse Rosario Argüello , Alencastro Carla Paola Espinoza
Published: November 2021

Este trabajo analiza la importancia del mercado educativo y la inclusión de medios tecnológicos para el proceso de transformación de las empresas tradicionales a negocios digitales; la investigación es documental de tipo descriptiva - exploratoria; en esta se examinó documentación científica y representativa de instituciones educativas de educación superior; esencialmente sobre servicios digitales y los efectos del COVID-19 en la manera de hacer negocios.

El objetivo de este paper fue indagar el proceso transformador de los servicios tradicionales a actividades comerciales con plataformas tecnológicas en el área educativa. A modo de resultado de este análisis, se observa una correlación entre los sucesos de la pandemia y el ineludible cambio de los negocios en la educación superior; comprobándose una innovación efectiva de una instrucción flexible y herramientas especializadas para la era actual.
Clinical significance of Epstein-Barr virus polymerase chain reaction in cerebrospinal fluid
Authors: Shin Yong Woo , Sunwoo Jun-Sang , Lee Han-Sang , Lee Woo-Jin , Ahn Seon-Jae , Lee Sang Kun , Chu Kon
Published: November 2021

Purpose: Epstein-Barr virus (EBV) is implicated in various neurological conditions. However, the relationship between EBV DNA in cerebrospinal fluid (CSF) and central nervous system (CNS) infection is unclear. We evaluated the clinical manifestation of patients with EBV DNA detected in CSF.Methods: We reviewed the medical records of patients admitted to Seoul National University Hospital from January 2000 to March 2021 who underwent EBV polymerase chain reaction (PCR) tests in CSF. The subjects were divided into positive and negative groups depending on the presence of EBV DNA, and further clinical information was obtained from positive patients.Results: CSF EBV PCR tests were performed in 807 patients, and 57 (7.1%) tested positive. Pleocytosis was common (81%) in CSF samples with EBV DNA detected, and the proportion was significantly higher than that in samples that were EBV PCR negative (44.5%, p < 0.0001). Among 57 patients with EBV DNA detected in CSF, 51 (89.5%) were diagnosed with CNS infection or inflammatory disorders. Of the 51 patients, 31 (60.8%) had possible etiologies other than EBV. Follow-up evaluation was conducted in 19 of 20 patients, and 63.2% showed a favorable outcome.Conclusion: Positive EBV PCR in CSF is mostly nonspecific and should be interpreted with caution. A comprehensive workup is needed to identify other etiologies before considering EBV as the sole culprit.
A Study on Various Phishing Techniques and Recent Phishing Attacks
Authors: Bhuvana  , Bhat Arundhathi S , Shetty Thirtha , Naik Mr. Pradeep
Published: November 2021

Now-a-days internet has become a very unsafe space to deal with. Hackers are constantly trying to gain the user's personal information, and detailed credentials. So many websites on the internet, even though safe, this safety cannot be assured by all websites. These rule breakers avoid abiding by rules, and try to employ methods like trickery and hacking to gain illegal access to private information. T o be able to overcome this problem, we need to first understand the intricacies of how the virus is designed. This paper mainly deals with the different phishing techniques and recent phishing attacks that took place during COVID 19. like Link Manipulation, Filter Evasion, Website Forgery, Phone Phishing and Website Forgery. We have also studied a subtle method to perform phishing attacks that makes links appear legitimate, but actually redirect a victim to an attacker's website called Convert Redirect. In this paper , we present some phishing examples like Paypal phishing which involves sending an email that fraudulently claims to be from a well known company and Rapidshare Phishing where in the spoofed web page, phishers attempt to confuse their victims just enough to entice them to enter their login name and password. To perform these types of phishing the Phishers uses so many phishing techniques like Link Manipulation, Filter Evasion, Website Forgery, Phone Phishing and Website Forgery. Phishing techniques include the domain of email messages. Phishing emails have hosted such a phishing website, where a click on the URL or the malware code as executing some actions to perform is socially engineered messages. Lexically analyzing the URLs can enhance the performance and help to differentiate between the original email and the phishing URL. As assessed in this study , in addition to textual analysis of phishing URL, email classification is successful and results in a highly precise anti phishing. From the thorough analysis of the research paper, we have understood how phishing attacks work and the different methods employed to carry out the attack. Also, we have studied some of the most recent phishing attacks and measures taken by the authorities to overcome and prevent any such attacks in future.
Translating Knowledge to Optimize Value-Based Occupational Therapy: Strategies for Educators, Practitioners, and Researchers
Authors: Juckett Lisa A. , Robinson Monica L. , Malloy Julie , Oliver Haley V.
Published: November 2021

With the continued evolution of health care reform and payment models, it is imperative that the occupational therapy profession consistently and clearly articulate its distinct value. As payment models shift from paying for the volume of services provided to paying for the value of services, the field of occupational therapy must be sure to implement high-quality care by translating evidence into practice and facilitating improvements in client outcomes. Yet the process of translating evidence-based interventions and programs to real-world settings can be quite complex, and successful implementation often requires active collaboration across occupational therapy stakeholders. In this Health Policy Perspectives article, we provide occupational therapy educators, practitioners, and researchers with key recommendations for how the profession can translate evidence into practice, ultimately leading to the improvement of client outcomes and the provision of value-based care.
Low-orbit satellite grouping of the system for monitoring geodesic parameters of the Earth and the direction of its development
Authors: Кузин С.П.
Published: November 2021

Спутниковые миссии наряду с наземными геодезическими сетями различных космических технологий являются второй важной составляющей российского сегмента системы контроля геодезических параметров Земли (ГПЗ). Спутники имеют неоспоримое преимущество в том, что они непрерывно собирают однородные данные над большими частями земной поверхности. Они позволяют сбор данных, которые не могут быть зарегистрированы на поверхности Земли. Такие спутники в наше время оборудованы множеством датчиков, контролирующих поверхности суши, океана и льда, а также гравитационное поле Земли и его временные изменения. Потенциал и влияние спутниковых миссий для наблюдений Земли значительно возрастут в связи с тем, что: (1) будут запускаться все больше и больше спутниковых созвездий, вместо отдельных спутников, увеличивая тем самым временное и пространственное разрешение получаемых данных; (2) спутники будут летать в «формированиях», образуя большие наблюдательные приборы, состоящие из датчиков, расположенных на нескольких спутниках. В работе автор, с учетом рекомендаций международного геодезического сообщества, предлагает набор низкоорбитальных спутниковых миссий различных направлений, необходимых для полноценного функционирования системы контроля ГПЗ, и рассматривает направления развития данных миссий.

Satellite missions, along with ground-based geodesic networks of various space technologies, will be the second important component of the Russian segment of the system for monitoring geodesic parameters of the Earth (GPE). Satellites have the undeniable advantage of continuously collecting uniform data over large parts of the Earth’s surface. They allow the collection of data that cannot be registered on the Earth’s surface. Such satellites are now equipped with a variety of sensors that monitor the surface of land, ocean and ice, as well as the Earth’s gravitational field and its temporal changes. The potential and impact of satellite missions for Earth observations will increase significantly as: (1) more and more satellite constellations will be launched, instead of individual satellites, thereby increasing the temporal and spatial resolution of the data received; (2) satellites will fly in “formations”, forming large observation instruments consisting of sensors located on several satellites. In this article the author taking into account the international geodetic community recommendations proposes a set of low-orbit satellite missions to various areas, necessary for proper operation of the system for monitoring GPE, and the directions of development of these missions are considered.
Strangeness of translational and rotational motion of the geosynchronous object 10294 according to optical observations
Authors: Бахтигараев Н.С.
Published: November 2021

Представлены особенности изменения параметров движения геосинхронного объекта 10294 SIRIO-1 №1977-080A по результатам оптических наблюдений в обсерваториях в Звенигороде, на пике Терскол и на горе Санглох республики Таджикистан. Пассивный итальянский научный космический аппарат SIRIO-1 представляет интерес тем, что он описывает классическую восьмерку вокруг точки либрации 75 ◦ в.д. без дрейфа по долготе и всегда доступен наблюдениям с наших пунктов. Это дает возможность детально исследовать поступательно-вращательное движение объекта, используя только результаты своих измерений. SIRIO-1 наблюдался нами для проверки аппаратуры и программного обеспечения как тестовый объект с очень устойчивой орбитой. В 2018 г. у этого объекта были обнаружены изменения в движении и в кривых блеска, не свойственные космическому мусору. Были зафиксированы небольшое скачкообразное изменение орбиты между 7 и 11 марта 2018 г. и изменение коэффициента отношения площади миделевого сечения объекта к его массе; кроме того перестал надежно определяться период изменения блеска и появилось характерное изменение блеска на одном и том же участке траектории с периодом, примерно равным звездным суткам.

The features of changes in the motion parameters of the geosynchronous object 10294 SIRIO-1 No.1977-080A based on the results of optical observations at the observatories in Zvenigorod, Terskol Peak and Sanglokh Mountain in the Republic of Tajikistan are presented. The passive Italian scientific spacecraft SIRIO-1 is of interest to us because it describes the classic eight around the libration point of 75 ◦ E without longitude drift and is always available to observations from our observation points. This makes it possible to study in detail the translational-rotational motion of the object, using only the results of their measurements. SIRIO-1 was observed by us to test the hardware and software as a test object with a very stable orbit. In 2018, this object was found to have changes in motion and in the light curves that are not characteristic to space debris. A small abrupt change in the orbit between March 7 and 11, 2018, and a change in the area-to-mass ratio of the object were recorded. In addition, the period of change in the brightness was no longer reliably determined, and a characteristic change in the brightness appeared on the same part of the trajectory with a period approximately equal to the sidereal day.
Progression in pediatric glaucoma: Lessons learnt from 8 years’ follow-up
Authors: Sharifipour Farideh , Arasteh Elahe , Hajizadeh Maryam , Mahdian-Rad Atefe , Mirdehghan Mohammad Sadegh
Published: November 2021

Background: Surgical procedures are used as 1 of the main treatment modalities for pediatric glaucoma, even though progression may occur. In this study, we aimed to investigate the risk factors affecting the progression of pediatric glaucoma.Methods: In this retrospective cohort study, we reviewed the medical records of patients diagnosed with pediatric glaucoma between April 2009 and March 2017. Pediatric glaucoma patients who underwent regular follow-up for at least 1 year were included. Demographics, intraocular pressure (IOP), central corneal thickness (CCT), axial length (AL), cup-to-disc ratio (C/D ratio), corneal diameter, type of glaucoma, age at time ofdiagnosis, and age at surgery were recorded. Progression was defined as an increase in AL > 2 mm, C/D ratio > 0.2, or corneal diameter > 1 mm during 1 year of follow-up.Results: Eighty-three eyes from 46 patients were included: 37 eyes (45%) with primary congenital glaucoma (PCG), 46 eyes (55%) with secondary glaucoma, and 27 of these 83 eyes (32.5%) showed progression. Progression was comparable between eyes with PCG and secondary glaucoma (PCG, 22%; secondary glaucoma, 41%; P = 0.152). Age at the time of diagnosis and age at the time of the first surgery were significantly lower in the eyes with progression (P = 0.046 and 0.012, respectively). The mean ± standard deviation of surgeries in progressed versus non-progressed eyes was 1.88 ± 1.1 versus 1 ± 0.8 (P = 0.015). The frequency of comorbid systemic disease was significantly higher in patients with glaucoma progression (P = 0.043). The progressed and non-progressed eyes were comparable in terms of other demographic characteristics and ocular parameters (allP > 0.05).Conclusions: Pediatric glaucoma patients who were younger at the time of diagnosis and the first glaucoma surgery and those with comorbid systemic disease are at higher risk of glaucoma progression. These findings are useful for clinicians when counseling parents of children with pediatric glaucoma about disease outcomes. However, future prospective studies with larger sample sizes and longer follow-up periods are needed to confirm our findings.
ПРОЦЕСС ОБУЧЕНИЯ ПАТРИОТИЗМУ И НАЦИОНАЛЬНОМУ САМООПРЕДЕЛЕНИЮ МОЛОДЕЖИ
Authors: Муродзода Мухсин
Published: November 2021

В этой статье автор выражает свои взгляды на воспитание патриотизма и его роль в укреплении национальной идентичности в таджикском обществе. По мнению автора, для укрепления национального единства, прежде всего, необходимо обеспечить стабильные и мирные условия жизни людей, подлинное равенство и полную дружбу и сотрудничество всех народов, наций и социальных групп. Автор убежден, что в современных условиях государственности необходимо защищать независимость национального государства, безопасность Родины, укреплять и развивать демократические институты, повышать общественное сознание и мировоззрение, познавать прошлое и укреплять национальную идентичность. Реализация этого важного вопроса - непростая задача, требующая дальновидной экономической, социальной и культурной политики.
ПРОГНОЗУВАННЯ ЗОН РОЗУЩІЛЬНЕННЯ В КРИСТАЛІЧНОМУ ФУНДАМЕНТІ ОЛИНСЬКОГО ГЕОБЛОКУ УКРАЇНСЬКОГО ЩИТА МЕТОДАМИ ГЕОФІЗИЧНОЇ ГОЛОГРАФІЇ
Authors: Баньковський Михайло , Гейхман Анатолій , Потапчук Іван
Published: November 2021

Застосована ідея про спільну хвильову природу усіх потенціальних полів у методі геофізичної голографії з метою побудови реального інструмента на допомогу сейсмічним методам як при вивченні глибинної будови Землі, так і при пошуках родовищ корисних копалин на території Коростенського плутону в умовах Українського щита.
SUSTAINABLE DEVELOPMENT ECONOMICS AND GLOBAL INVESTMENT TRENDS
Authors: Kaiyrbek Meruyert , Aituova Darina , Kulpeisova Saule
Published: November 2021

This article provides a brief overview of current global trends in the development of a sustainable economy, as well as investment trends. Among the identified trends, the following are noted: the predominance of economic interests of states over political differences, the formation of a multipolar world, the rapid growth rates of technologization and digitalization, their merging with all spheres of life, the rapid development of the IT sphere, the formation of new energy trends against the background of the structural transformation of energy balances, qualitative methodological changes in the field of education, demographic and environmental problems, as well as the COVID-19 pandemic. Currently, the needs in the field of international investment are significantly high. Problems related to the role of investments in the development of the world economy are considered. The issues of using investment resources to achieve the goals of sustainable development of the world economy are gaining priority. It is noted that for the implementation of an effective economic policy, countries need to attract foreign investment. The analysis carried out in the article confirms that the investment attractiveness of the country, the stability of the national financial system, and the legal protection of entrepreneurship play a decisive role in attracting foreign direct investment.