bluuebunny/crossref_metadata_2025 huggingface dataset:
On the peculiarities of preparation of patients with venous trophic ulcer in outpatient conditions for the performance of radiofrequency ablation of veins
Authors: Goshchynsky V.B. , Mihenko B. O. , Sviderskyi Y.Y.
Published: April 2022

Annotation. The number of patients with venous trophic ulcer is constantly growing. At the same time, there is no effective method of their treatment in outpatient conditions. This issue is of fundamental importance for reducing the period of preparation of patients for radiofrequency ablation (RFA)of varicose veins. The aim of the study. The purpose of the study was: to give a clinical justification for the use of ultrasound debridement, PRP and PRF therapy to stimulate the regeneration process in venous ulcers in outpatient settings, for the aim of prepare patients for the implementation of RFA varicose veins. Under observation were 75 patients with varicose veins of the lower extremities in the stage of decompensation (C6 according to the CEAP classification). There were 49 women, 26 men, 55±4.6 years old. The duration of existence of venous ulcers was 2.1±06 years. The average size of ulcers is 4.5±1.7 cm. Ultrasound debridement was used to purify venous ulcers from necrotic masses, followed by stimulation of the regeneration process in them through PRP and PRF therapy. Thanks to the use of ultrasound debridement, it was possible to translate the chronic inflammatory process into an acute one. So, after the first session of ultrasound debridement, the wounds are regenerative and inflammatory in nature, which is confirmed by their cytological examination. Further use of PRP and PRF as a local factor in stimulating the regeneration process in venous ulcer caused the transition of regenerative-inflammatory to regenerative type of ulcer healing. Thanks to this approach to the treatment of venous ulcers, it was possible to reduce the time for surgical training of patients by 1.87 times. Treatment of venous ulcers, including ultrasound debridement – stimulation of the wound process PRP and PRF followed by operations aimed at eliminating the causes of decompensated chronic insufficiency is a promising direction in the treatment of varicose veins in outpatient settings.
A mathematical prognosis modelling of reocclusions in patients with occlusive-stenotic diseases of the main arteries of the infrarenal aorta
Authors: Shaprynskyi V. V. , Shaprynskyi V. O. , Ocheredko O. M.
Published: April 2022

Annotation. Obliterating atherosclerosis the lower extremities vessels often leads to permanent disability and mortality in some cases. Despite the improvement of methods and techniques of endovascular and open operations, nowadays there is still a significant frequency of amputations due to progression of atheroscleroses and various intra- and postoperative complications, such as shunt thrombosis or thrombosis of zone of reconstruction. Therefore, the aim was to research the factors influencing the occurrence of reocclusion after surgery and to develop predictive modeling of the risk of their occurrence with the help of logistic mathematical regression. 100 patients with occlusive-stenotic lesions of the main arteries of the infrarenal aorta by atherosclerotic origin were examined. 50 patients (general group) revealed reocclusion occurred in the early postoperative period, and 50 patients (comparison group) have no reocclusion. The factors influencing the occurrence of reocclusion have been identified, and mathematical prognostic modeling of reocclusions based on logistic regression has been created. It was found that the risk of reocclusion increases significantly with increasing duration of the lesion (b=0.5214, p=0.005), in the presence of complex anatomical conditions (b=3.5080, p=0.034), in the presence of two or more multistory occlusions (b=9.0073, p=0.002), in the presence of technical errors in the intervention process (b=8.0802, p=0.004).
Analysis of the redistribution of rs4977574-polymorphic variants of the ANRIL gen in patients with acute coronary syndrome of different sex
Authors: Kniazkova P. V. , Harbuzova V. Yu.
Published: April 2022

Annotation. The aim of the study was to analyze the distribution of rs4977574-polymorphic variants of the ANRIL gene in patients with acute coronary syndrome of different sex. The venous blood of 234 patients with acute coronary syndrome (ACS) and 195 people without cardiac pathology was used for the study. DNA was isolated from whole venous blood using the GeneJET Whole Blood Genomic DNA Purification Mini Kit (ThermoFisher Scientific, USA). rs4977574 ANRIL gene polymorphism was studied by real-time PCR reaction in the presence of TaqMan assay C_31720978_30. Statistical analysis of the study was performed using the SPSS program (version 17.0). A difference was found when comparing the frequencies of genotypes at the polymorphic site rs4977574 of the ANRIL gene in their distribution (p=0,035). According to the results of logistic regression, it was detected that in the recessive (p=0,015) and additive (p=0,012) inheritance models, carriers of the G/G genotype are approximately 2 times more likely to develop ACS than carriers of the A-allele. The reliability of the results was maintained after adjustments for gender, age, B<I, smoking habits, diabetes and stress (p=0,049 for the recessive model; p=0,037 for the additive model). Thus, individuals with the rs4977574 G/G genotype polymorphism of the ANRIL long non-coding RNA gene have a 2 times higher risk of developing ACS than dominant allele carriers. Further research will focus on the association of ANRIL polymorphism with the risk of ACS depending on other risk factors.
Abdominal pain in children with intraabdominal purulent diseases and acute complications of type I diabetes mellitus: a non-systematic review
Authors: Yakymenko O. , Suchok S.
Published: April 2022

Annotation. The prevalence of type I diabetes mellitus (T1DM) among children in Ukraine reached 9105 patients in 2018 and continues to rise. Differential diagnosis of abdominal pain in ketoacidosis and intraabdominal purulent diseases is an important factor contributing to prompt and appropriate management of such patients. We analyzed the prevalence of T1DM in different age groups and specific features of abdominal pain related to its complications and concomitant intraabdominal purulent diseases in childhood in this article. Scientific research for the period from 2008 to 2021 was carried out according to the primary search strategy “type I diabetes mellitus” (T1DM, pediatric, children, prevalence), “ketoacidosis” (ketoacidosis, diabetic ketoacidosis, children), “abdominal pain” (acute abdominal pain, children), “acute appendicitis” (acute appendicitis, pediatric, children) and the combination of AND/OR in the scientometric databases MEDLINE (PubMed), Scopus, Web of Science. The leading role in the pathogenesis of pain belongs to electrolyte imbalance (acidosis) arising from the accumulation of intermediate products of fat oxidation. Abdominal pain in intraabdominal purulent diseases includes visceral, somatic parietal, and irradiating elements. The coincidence of onset peaks of intraabdominal purulent diseases, accompanied by acute abdominal pain and T1DM in this population requires the development of a standardized algorithm for the differential diagnosis of these pathologies.
PROSPECTS OF APPLICATION OF THE LATEST PLANT-VITAMIN COMPLEX FOR PREVENTION AND TREATMENT OF ESTROGEN-DEPENDENT DISORDERS IN GYNECOLOGY
Authors: Zaychenko G. V  , Карпенко Н. О.  , Ravshanov T. B.
Published: April 2022

Possibilities and prospects of correcting women's health disorders associated with hypoestrogenic conditions of various etiologies or hormonal imbalances are considered. The causes of estrogen deficiency and features of complaints in women of different ages with an emphasis on peri- and menopause are systematized. An alternative to menopausal hormone therapy (MHT) with the use of phytovitamin preparations is considered. The relationship of hormonal metabolism with vitamin and mineral status, feasibility and benefits of complex phyto-, vitamin- and mineral preparations is shown. The therapeutic efficacy of medicinal plants that are part of the complex phytopreparation "Forevia Maxi" ("Organosyn LTD") in accordance with the symptoms of premenstrual syndrome (PMS): vasomotor (shortness of breath, hot flushes, night sweats, blood pressure fluctuations), genitals and atrophy of the vagina, itching, burning, cystalgia, urinary incontinence, dyspareunia) complications, memory and cognitive impairment, decreased sexuality, libido, sleep disorders, mood swings, anxiety, depression, aggravating psycho-emotional state, osteoporotic changes. Data from clinical trials of phytoextracts are shown, which demonstrate that the effect of the components of Forevia Maxi significantly exceeds the effect of placebo, and sometimes not less than with the use of MHT. The obvious benefits of this tool and as an adjunct to the basic therapy of PMS and hypoestrogenic conditions, characterized by ease of use, good safety profile, allows you to individualize the approach to patients, which is important in cases of medical contraindications for hormone therapy. Forevia Maxi is also the most appropriate for use with MHT, as an additional component of the correction of hypothalamic-pituitary disorders and saturation of the body with essential minerals and vitamins.
Mono- and Bimetallic Silver-Containing Nitrogen-Doped Carbon Composites and Their Electrocatalytic Activity
Authors:   Institute of Organic Synthesis and Coal Chemistry of the Republic of Kazakhstan, Vissurkhanova Ya.A. , Ivanova N.M. ,   Institute of Organic Synthesis and Coal Chemistry of the Republic of Kazakhstan, Soboleva E.A. ,   Institute of Organic Synthesis and Coal Chemistry of the Republic of Kazakhstan, Mukhamedzhanova A.K. ,   Institute of Organic Synthesis and Coal Chemistry of the Republic of Kazakhstan
Published: April 2022

The N-doped metal-carbon composites based on the carbonized melamine-formaldehyde polymer (MFP) with silver, silver-copper, and silver-cobalt particles were synthesized. Mono- and bimetallic silver-containing composites were prepared by the reduction of metal nitrates with hydrazine hydrate in an aqueous ethanol medium in the presence of carbon black particles obtained by the heat treatment of MF-polymer at 500 °C. The structural-phase changes before and after the use of metal-carbon composites as electrocatalysts in the electrohydrogenation of p-nitroaniline (p-NA) were studied by X-ray diffraction analysis. The morpho-logical features of the created MFBC + Ag, MFBC + (Ag+Cu) and MFBC + (Ag+Co) composites were stud-ied by electron microscopy. It was established that the synthesized composites mainly contain crystalline phases of the corresponding reduced metals or their alloys. The monometallic MFBC(1) + Ag(1) composite contains reduced silver crystallites of various shapes and localization on porous MF carbon black particles. Higher electrocatalytic activity of the synthesized Ag-containing composites in the p-NA electrohydro-genation was shown in comparison not only with the electrochemical reduction of p-NA but also with MFBC + (Ag+Cu) composites with electrocatalytic hydrogenation of p-NA on Ag + Cu particles (without MFBC). It was found that the use of the studied MFBC-composites increases the selectivity of the formation of the main hydrogenation product (p-phenylenediamine) and decreases the yields of by-products.
Ikon, Indeks, dan Simbol dalam Kumpulan Cerpen Menghardik Gerimis Karya Sapardi Djoko Damono serta Relevansinya dengan Pembelajaran Bahasa Indonesia di Madrasah Aliyah
Authors: Jannah Marfu'ah nur , Inderasari Elen
Published: April 2022

Abstract
This study aims to describe semiotic signs in the form of icons, indexes, and symbols contained in the short story collection Menghardik Gerimis by Sapardi Djoko Damono (SDD) and their relevance to learning Indonesian at Madrasah Aliyah. This study uses a qualitative descriptive method with semiotic analysis of Charles Sanders Peirce. Data collection techniques in this study used reading and note-taking techniques. The data collection technique used purposive sampling technique, namely the sampling of data sources with certain considerations. Based on the results of the analysis and discussion found: (1) icons, including icons of natural phenomena, plants, animals, celestial bodies, landscapes, religion, and objects created by humans. (2) index, which includes the index of sound, nature, and the nature of human behavior. (3) symbols, including symbols of color, animal, social, spiritual, and philosophy of life. (4) the building blocks of the short story, including the intrinsic and extrinsic elements in accordance with the learning of short stories at Madrasah Aliyah.
Abstrak

           Penelitian ini bertujuan untuk mendeskripsikan tanda semiotika berupa ikon, indeks, dan simbol yang terdapat dalam kumpulan cerpen Menghardik Gerimis karya Sapardi Djoko Damono (SDD) serta relevansinya dengan pembelajaran bahasa Indonesia di Madrasah Aliyah. Penelitian ini menggunakan metode deskriptif kualitatif dengan analisis semiotika Charles Sanders Peirce. Teknik pengumpulan data di dalam penelitian ini menggunakan teknik baca dan catat. Teknik pengambilan data menggunakan teknik purposive sampling yaitu pengambilan sampel sumber data dengan pertimbangan tertentu. Berdasarkan hasil analisis dan pembahasan ditemukan: (1) ikon, mencakup ikon fenomena alam, tumbuhan, binatang, benda langit, bentang alam, religi, dan benda ciptaan manusia. (2) indeks, mencakup indeks suara, alam, dan sifat perilaku manusia. (3) simbol, mencakup simbol warna, binatang, sosial, spiritual, dan falsafah hidup. (4) unsur pembangun cerpen, yakni unsur intrinsik dan ekstrinsik yang sesuai dengan pembelajaran cerpen di Madrasah Aliyah.
Test of ocean tide loading models on the basis of strain data measured at the Vyhne Tidal Station, Slovakia
Authors: BRIMICH Ladislav , BEDNÁRIK Martin , BÓDI Jozef , MENTES Gyula
Published: April 2022

Tidal strain time series recorded at the Vyhne Tidal Station are used to test thirteen different ocean tide loading models. Ten models have been calculated using SPOTL: EOT11a, HAMTIDE11a, OSU.TPXO72atlas, OSU.TPXO72, TPX070, DTU10, CSR4.0, FES2004, FES95.2.1, SCHW1 and three other models were chosen from the Free Ocean Tide Loading Provider (FOTLP) created by Scherneck and Bos: FES2012, FES2014b, GOT00.2. Hourly sampled strain data, corrected for temperature, were subjected to correction for ocean tide loading. The test of models was focused on the diurnal and semi-diurnal tidal harmonic constituents O1, P1, K1 and M2. A negligible difference between the individual global ocean tide loading models was only found mainly due to using different Earth models and Green functions. The amplitude factors for O1, P1, K1 and M2 derived from the measurements are 1.019, 1.226, 0.842 and 1.131, respectively. The average amplitude factors for these tidal components were obtained after ocean load correction using SPOTL routines: 1.121, 1.332, 0.916, 1.283, and in the case of the three models using FOTLP: 1.046, 1.486, 1.067, 1.317. The corrected amplitude factor became closer to the theoretical value only for K1.
Determination of the stress field in the Kopeh Dagh and Eastern Iran regions
Authors: ROSTAM Ghasem Ghorbani
Published: April 2022

The land of Iran is situated in a compression zone with a high seismicity rate due to the convergence of Arabian and Eurasian plates. In this study, the stress field of two provinces of Kopeh Dagh and Eastern Iran, which are located in the east and northeast of Iran, has been studied and compared. These two provinces are different in terms of seismicity patterns so that Kopeh Dagh is much more active than Eastern Iran. To achieve this goal, the iterative joint inversion method for stress and fault orientations developed by Vavryčuk (2014) has been used. The average direction of the maximum principal stress (σ1) and the maximum horizontal stress (SHmax) in the study area are estimated to be N30.1°E and N12.1°E, respectively. These directions are in agreement with the convergence of the Arabian plate and the Eurasian plate. The value of the optimal friction coefficient was determined for both regions and it was found that this coefficient is lower in Kopeh Dagh than in Eastern Iran. This indicates a potential relationship of the fault friction with the activity pattern and seismicity of in the region.
FACTORS CAUSING PARTAI DEMOKRAT INDONESIA VICTORY IN THE 2019 LEGISLATIVE ELECTION IN LAMPUNG PROVINCE
Authors: Widia Novita Lukitasari WA
Published: April 2022

The Indonesian Democratic Party of Struggle in Lampung Province is one of several parties that participated in the 2019 legislative elections and through the rule of law, the PDI-P has the most seats in the Lampung Provincial DPRD, then has the right to propose its cadres to sit as Chair of the Lampung Provincial DPRD.. The focus of writing the paper is the factor that caused the PDI-P's victory in the 2019 Legislative Election in Lampung Province.Peinfluence figures have a dominant role in the electoral system that uses the majority vote system. Competence and credibility of candidates for imaging and electability of the candidates concerned. The key to the PDI-P's victory in the 2019 election in Lampung Province is having militancy capital or traditional voters who are loyal to the party's choice. The nationally valid traditional electorate is the first determining factor. Next is the high level of penetration of legislative candidates in influencing voters.
EVALUASI PERENCANAAN PEMBANGUNAN WILAYAH KEPULAUAN RIAU TAHUN 2019
Authors: Naharuddin Naharuddin
Published: April 2022

Provinsi Kepulauan Riau yang wilayahnya didominasi 96% perairan dan hanya 4% daratan memiliki potensi kemaritiman yang luar biasa. Namun isu-isu strategis pembangunan masih terjadi, kesenjangan pembangunan antar wilayah dan optimalisasi penanganan wilayah perbatasan, pulau-pulau terdepan dan pulau-pulau kecil untuk peningkatan kesejahteraan masyarakat merupakan pekerjaan rumah yang harus diselesaikan. Perencanaan pembangunan yang selama ini dilakukan belum memprioritaskan sektor kemaritiman sebagai prioritas pembangunan wilayah. Penelitian ini bertujuan untuk menganalisa proses perencanaan pembangunan wilayah dan faktor-faktor yang menyebabkan belum optimalnya perencanaan pembangunan wilayah Kepulauan Riau tahun 2019. Proses perencanaan pembangunan dianalisa dan dideskripsikan mengunakan tiga indikator dalam teori evaluasi perencanaan pembangunan Willian N. Dunn, yakni: (1) Efisiensi; (2) Perataan; dan (3) Responsiitas. Metode penelitian digunakan adalah metode penelitian kualitatif. Hasil penelitian menunjukkan bahwa walaupun proses perencanaan pembangunan yang dimulai dari pentahapan dan penjadwalan yang dilakukan oleh Pemerintah Provinsi Kepulauan Riau dalam penyusunan Rencana Kerja Pemerintah Daerah tahun 2019 telah sesuai dan partisipasi Stakeholder dalam Musrenbang juga cukup baik, namun capaian kinerja yang tertuang dalam perjanjian kinerja Kepala Daerah pada akhir tahun ditemukan 25% target kinerja yang belum tercapai. Pendekatan yang dilakukan dalam proses perencanaan pembangunan juga masih menggunakan kaidah normatif, yaitu berorientasi pada perencanaan pembangunan berbasis wilayah daratan (continental approach) yang seharusnya menggunakan pendekatan berbasis wilayah kepulauan (ocean approach).
O desenvolvimento profissional docente em diálogo com as concepções teóricas de pierre bourdieu: a constituição do habitus profissional no ensino de história
Authors: Sena Mariano André Luiz , Lopes de Freitas Leonardo
Published: April 2022

Este artigo objetiva compreender aspectos do desenvolvimento profissional docente tentando relacioná-lo com ao conceito de habitus proposto por Bourdieu. Participaram do estudo professoras graduadas em Pedagogia e atuantes no ensino de História nos anos iniciais do ensino fundamental. O texto procura explorar os condicionantes associados as escolhas, experiências e costumes que cercam o cotidiano escolar e formativo das participantes da pesquisa. Procura ressaltar os elementos estruturantes da prática pedagógica que vão para além do capital cultural institucionalizado, tentando mostrar que, apesar de as professoras estarem submetidas a um mesmo percurso formativo, os determinantes da prática acabam obedecendo a uma dimensão subjetiva, ou seja, cada uma apresenta fontes e formas próprias para a formação do seu habitus profissional e para a organização de sua prática profissional.
O Processo de construção da BNC-Formação a partir de seu contexto de influência
Authors: Caporal Carolina , Da Rocha Vieira Gonçalves Suzane
Published: April 2022

Este artigo busca contribuir para a análise da Base Nacional Comum para a Formação Inicial de Professores da Educação Básica (BNC-Formação) a partir da abordagem do ciclo de políticas e da pesquisa qualitativa. Destaca-se que para a escrita nos atentamos diretamente na análise do seu contexto de influência, apresentada como política educacional neoliberal e evidenciando um projeto político ancorado em concepções gerencialistas de Estado. Ao considerar a pesquisa qualitativa enquanto elemento principal da construção do caminho metodológico para análise de políticas públicas, busca-se tecer significações acerca de como unir a pesquisa qualitativa a abordagem do ciclo de políticas. É notável como a pesquisa qualitativa, a abordagem do ciclo de políticas e análise de documentos de política educacional são intrínsecas à uma análise comprometida com uma compreensão crítica e aprofundada da realidade e que busque romper com uma visão linear e fechada das políticas educacionais.
Safety and feasibility of intramedullary injected bone marrow–derived mesenchymal stem cells in acute complete spinal cord injury: phase 1 trial
Authors: Saini Renu , Pahwa Bhavya , Agrawal Deepak , Singh Pankaj , Gurjar Hitesh , Mishra Shashwat , Jagdevan Aman , Misra Mahesh Chandra
Published: April 2022

OBJECTIVE

The intramedullary route holds the potential to provide the most concentration of stem cells in cases of spinal cord injury (SCI). However, the safety and feasibility of this route need to be studied in human subjects. The aim of this study was to evaluate the safety and feasibility of intramedullary injected bone marrow–derived mesenchymal stem cells (BM-MSCs) in acute complete SCI.

METHODS

In this prospective study conducted over a 2-year period, 27 patients with acute (defined as within 1 week of injury) and complete SCI were randomized to receive BM-MSC or placebo through an intramedullary route intraoperatively at the time of spinal decompression and fusion. Institutional ethics approval was obtained, and informed consent was obtained from all patients. Safety was assessed using laboratory and clinicoradiological parameters preoperatively and 3 and 6 months after surgery.

RESULTS

A total of 180 patients were screened during the study period. Of these, 27 were enrolled in the study. Three patients withdrew, 3 patients were lost to follow-up, and 8 patients died, leaving a total of 13 patients for final analysis. Seven of these patients were in the stem cell group, and 6 were in the control group. Both groups were well matched in terms of sex, age, and weight. No adverse events related to stem cell injection were noted for laboratory and radiological parameters. Five patients in the control group and 3 patients in the stem cell group died during the follow-up period.

CONCLUSIONS

Intramedullary injection of BM-MSCs was found to be safe and feasible for use in patients with acute complete SCI.
Optimal timing of referral for nerve transfer surgery for postoperative C5 palsy
Authors: Saadeh Yamaan S. , Chopra Zoey , Olsen Eric , Smith Brandon W. , Kashlan Osama N. , Yang Lynda J. S. , Park Paul
Published: April 2022

OBJECTIVE

Cervical nerve 5 palsy can occur following surgery for cervical spine pathology. The prognosis of C5 palsy is generally favorable, and most patients recover useful function. However, some patients do not recover useful strength. Nerve transfers are a potential effective treatment of postoperative severe C5 palsy. This study aimed to further delineate the natural history of recovery from postoperative C5 palsy, determine whether lack of recovery at specific time points predicts poor recovery prognosis, and thereby determine a reasonable time point for referral to a complex peripheral nerve specialist.

METHODS

The authors conducted a retrospective review of 72 patients who underwent surgery for cervical spondylosis and stenosis complicated by C5 palsy. Medical Research Council (MRC) motor strength grades were recorded preoperatively; immediately postoperatively; at discharge; and at 2 weeks, 3 months, 6 months, and 12 months postoperatively. Univariate and multivariate logistic regression models were used to identify demographic and clinical risk factors associated with recovery of useful strength after severe C5 palsy.

RESULTS

The mean patient age was 62.5 years, and 36.1% of patients were female. Thirty patients (41.7%) experienced severe C5 palsy with less than antigravity strength (MRC grade 2 or less) at discharge. Twenty-one (70%) of these patients recovered useful strength (MRC grade 3 or greater) at 12 months postoperatively, and 9 patients (30%) did not recover useful strength at 12 months. Of those patients with persistent severe C5 palsy at 3 months postoperatively, 50% recovered useful strength at 12 months. Of those patients with persistent severe C5 palsy at 6 months postoperatively, 25% recovered useful strength at 12 months. No patient with MRC grade 0 or 1 strength at 6 months postoperatively recovered useful strength. A history of diabetes was associated with the occurrence of severe C5 palsy. On multivariate analysis, female sex was associated with recovery of useful strength.

CONCLUSIONS

Most patients with severe C5 palsy recover useful strength in their C5 myotome within 12 months of onset. However, at 3 months postoperatively, patients with persistent severe C5 palsy had only a 50% chance of recovering useful strength by 12 months. Lack of recovery of useful strength at 3 months postoperatively is a reasonable time point for referral to a complex peripheral nerve center to establish care and to determine candidacy for nerve transfer surgery if severe C5 palsy persists.
Pendidikan Kecerdasan Moral Sebagai Penguatan Kepribadian Siswa Era Industry 4.0.
Authors: Hafsah Hafsah , Afni Afni
Published: April 2022

Kecerdasan moral merupakan suatu kecerdasan yang membutuhkan perasaan yang empati, sukarela, toleransi dan bekerjasama untuk mencapai suatu tujuan. Tujuan dalam artikel ini untuk menjelaskan pendidikan kecerdasan moral sebagai model penguatan kepribadian siswa pada era industry 4.0. Metode penelitian yang digunakan adalah metode kualitatif dengan menggunakan pendekatan studi literature. Data primer dalam penelitian ini adalah data yang diperoleh dari hasil penelitian, artikel ilmiah, prosiding, skripsi dan buku yang relevan sedangkan data sekunder berupa buku-buku yang relevan. Metode pengumpulan data dalam peneltian ini yaitu, observasi, dan analisis dokumen. Analisis data dilakukan dengan menggunakan analisis deskriptif. Hasil penelitian ini menunjukkan bahwa pendidikan kecerdasan moral di era industri 4.0 sangat penting dilakukan untuk memberikan penguatan nilai moral kepada anak. Cara yang dapat dilakukan yaitu mendidik, mmebina, memiliki integritas, bertanggung jawab dan berperilaku jujur. Jadi kecerdasan moral merupakan simbol mewujudkan anak yang beraklak mulia dan bermoral tinggi.Moral intelligence is an intelligence that requires feelings of empathy, volunteerism, tolerance and cooperation to achieve a goal. The purpose of this article is to explain moral intelligence education as a model for strengthening students' personalities in the industrial 4.0 era. The research method used is a qualitative method using a literature study approach. Primary data in this study is data obtained from research results, scientific articles, proceedings, theses and relevant books, while secondary data is in the form of relevant books. The data collection methods in this research are observation, and document analysis. Data analysis was carried out using descriptive analysis. The results of this study indicate that moral intelligence education in the industrial era 4.0 is very important to do to provide reinforcement of moral values to children. Ways that can be done are educating, fostering, having integrity, being responsible and behaving honestly. So moral intelligence is a symbol of realizing children who have noble character and high morals.
Desain Pola Integrasi Cyber dalam Mengurangi Kejahatan Cyberbullying
Authors: Sakban Abdul , Bidaya Zaini
Published: April 2022

Dampak akibat dibully adalah depresi berat oleh si remaja korban bullying makin besar bahkan ke arah bunuh diri, menyakiti diri sendiri kepada si anak hasil bully. Tujuan penelitian ini adalah untuk menguraikan desain pola integrasi untuk mengurangi kejahatan cyberbullying. Metode yang digunakan dalam penelitian ini adalah penelitian kualitatif dengan pendekatan deskriptif analitis dan studi kasus. Sasaran subyek penelitian adalah aparat sipil negera, pegawai dan staf yang pada Kepolisian Daerah, Kemenkominfo, Telkom dan Pengadilan Negeri di Nusa Tenggara Barat metode pengumpulan data menggunakan studi kepustakaan, pengamatan, wawancara, analisis dokumen. Desain formulasi pola integrasi cyber dalam penelitian ini menggunakan desain grounded theory menurut Urguhard. Data yang terkumpul baik berupa data kepustakaan maupun data lapangan akan dianalisis dengan menggunakan deskriptif analitis untuk menguraikan data lapangan dengan studi literatur dengan pendekatan deduktif dan induktif. Hasil penelitian menunjukkan bahwa  pola integrasi cyber untuk pencegahan cyberbullying menggunakan sistem siklus cyber dengan tahapan yaitu kolaborasi lembaga, pencegahan melalui penyuluhan, edukasi, kampanye dan pendampingan (PEKP), Patroli Siber, menjaga identitas, menjadi saksi ahli, mengklarifikasi berita hoax menjadi berita yang asli, dan memberikan efek jera kepada pelaku kejahatan cyberbullying.The impact of being bullied is that the teenager who is bullied suffers from severe depression, even leading to suicide, hurting himself or herself to the child who is the result of being bullied. The purpose of this study is to describe the design of integration patterns to reduce cyberbullying crimes. The method used in this research is qualitative research with descriptive analytical approach and case studies. The target subjects of the study were state civil servants, employees and staff at the Regional Police, the Ministry of Communication and Informatics, Telkom and the District Court in West Nusa Tenggara. The data collection methods used were library research, observation, interviews, and document analysis. The design of the cyber integration pattern formulation in this study uses a grounded theory design according to Urguhard. The data collected in the form of library data and field data will be analyzed using analytical descriptive to describe the field data by studying literature with deductive and inductive approaches. The results show that the cyber integration pattern for cyberbullying prevention uses a cyber cycle system with stages, namely institutional collaboration, prevention through counseling, education, campaigns and mentoring (PEKP), Cyber Patrol, maintaining identity, being an expert witness, clarifying hoax news into original news. , and provide a deterrent effect to perpetrators of cyberbullying crimes.
Pembelajaran PPKn di Masa Pandemi Covid-19: Integrasi Learning Management System dan Online Assessment di SMP Muhammadiyah 7 Surakarta
Authors: Wardani Tata Aulia , Ilham Muhammad Nabil , Prasetyo Wibowo Heru , Sa`diyah Halimah
Published: April 2022

Pandemi virus Corona atau Covid-19 Pandemi merupakan kondisi yang tidak diinginkan yang terjadi di seluruh dunia. Dampak Covid-19 adalah beberapa kegiatan yang seharusnya dilakukan secara berkelompok atau bersama-sama merupakan kegiatan sehari-hari harus mengalami pembatasan. Semua sektor dipengaruhi oleh pembatasan ini sehingga aktivitas di semua sektor di transfer secara online. Salah satunya bidang pendidikan, kegiatan belajar mengajar dialihkan menjadi pembelajaran jarak jauh atau pembelajaran online. Artikel ini bertujuan untuk mendeskripsikan penggunaan Google Classroom Learning Management System dan Google Meet sebagai Online Assessment pembelajaran PPKn pada masa pandemi Covid-19 di SMP Muhammadiyah 7 Surakarta. Penelitian ini menggunakan pendekatan kualitatif dengan teknik pengumpulan data menggunakan metode observasi dan wawancara dengan guru mata pelajaran PPKn dan siswa kelas 9A Global. Teknik analisis data yang digunakan adalah menarik kesimpulan dari hasil wawancara dan observasi. Hasil riset menunjukkan bahwa tulisan ini merupakan fakta yang diperoleh dalam pelaksanaan observasi yang dilakukan terhadap pembelajaran PPKn pada saat pandemi Covid-19 di SMP Muhammadiyah 7 Surakarta selama pandemi Covid-19.The Corona virus pandemic or the Covid-19 Pandemic is an undesirable condition that occurs around the world. The impact of Covid-19 is that several activities that should be carried out in groups or collectively and constitute daily activities must experience restrictions. All sectors are affected by this restriction so that activities in all sectors are transferred online. One of them is the education sector, teaching and learning activities are shifted into distance learning or online learning. This article aims to describe the usage Google Classroomas Learning Management Systemand Google Meet as an Online Assessment of PPKn learning during the Covid-19 pandemic at SMP Muhammadiyah 7 Surakarta. This study used a qualitative approach with data collection techniques using the method of observation and interviews with PPKn subject teachers and students of class 9A Global. The data analysis technique used is drawing conclusions from the results of interviews and observations. The results of this article are facts obtained in the implementation of observations made on PPKn learning during the Covid-19 pandemic at SMP Muhammadiyah 7 Surakarta.during the Covid-19 pandemic.
Dampak-Dampak Terjadinya Perkawinan Anak di Era Pandemi Covid-19
Authors: Maemunah Maemunah , Hafsah Hafsah
Published: April 2022

Dampak dari Pandemi covid-19 pada perkawinan pernikahan dini dipengaruhi oleh budaya, masalah ekonomi yang menyebabkan orang tua mengizinkan anak-anaknya menikah di usia dini, pernikahan di anggap sebagai jalan pintas meringankan beban orangtua, aktivitas belajar dirumah mengakibatkan remaja memiliki keleluasaan dalam bergaul dilingkungan. Metode penelitian yang digunakan dalam penelitian ini adalah metode penelitain hukum empiris. Metode pengumpulan data menggunakan metodeo bservasi, wawancara, dokumentasi, sedangkan teknik analisis data melalui tahapan reduksi data, penyajian data, dan penarikan kesimpulan. Hasil penelitian bahwa dampak perkawinan anak terhadap jumlah  kekerasan dalam rumah tangga (KDRT) memiliki dampak negatif yaitu dampak yang tidak hanya merugikan anak maupun keluarga, tetapi secara keseluruhan juga merugikan Negara, akibat BDR sehingga peserta didik melakukan pernikahan tanpa memikirkan masa depan, terganggunnya kesehatan mental anak dan ibu, munculnya pola asuh yang saah pada anak, hingga intifikasi anak yang tidak tercatat karena tidak memiliki akta kelahiran, sehingga memunculkan resiko terburuk yaitu terjadinya perdagangan anak.The impact of the Covid-19 pandemic on early marriage is influenced by culture, economic problems that cause parents to allow their children to marry at an early age, marriage is considered a shortcut to lighten the burden on parents, learning activities at home result in teenagers having the flexibility to socialize in their environment. The research method used in this study is an empirical legal research method. The data collection method used observation, interviews, documentation, while the data analysis technique was through the stages of data reduction, data presentation, and drawing conclusions. The results of the study show that the impact of child marriage on the number of domestic violence (KDRT) has a negative impact, namely the impact that is not only detrimental to the child and family, but overall it is also detrimental to the State, due to BDR so that students marry without thinking about the future, mental health disorders children and mothers, the emergence of legal parenting patterns for children, to identification of children who are not registered because they do not have birth certificates, thus creating the worst risk, namely the occurrence of child trafficking.
Pentingnya Pembelajaran College Ball untuk menumbuhkan Sikap Toleransi
Authors: Rejeki Sri , Nurafiah Nurafiah
Published: April 2022

Pergeseran sikap toleransi siswa dipengaruhi oleh kurang optimalnya penguatan pembelajaran pendidikan kewarganegaraan, media pembelajaran terbatas sehingga penyampaian materi tidak tersampaikan dengan tuntas. Tujuan tulisan ini untuk menguraikan pentingnya pembelajaran college ball untuk menumbuhkan sikap toleransi siswa. Metode penelitian dalam penelitian ini adalah penelitian kualitatif dengan menggunakan pendekatan deskriptif dan studi literature. Pengumpulan data menggunakan data studi pustaka (digunakan untuk mengkaji artikel ilmiah tentang pembelajaran college ball, sikap toleransi), analisis dokumen  (digunakan untuk menganalisis terkait kebijakan pendidikan, makalah, hasil penelitian dan artikel ilmiah terkait pembelajaran college ball dan sikap toleransi). Analisis data menggunakan analisis deskriptif. Hasil penelitian menunjukkan bahwa penting pembelajaran college ball untuk menumbuhkan sikap toleransi siswa dapat menggunakan prinsip pembelajaran terbuka, pembelajaran kelompok, dan pembelajaran bermain game. Untuk menumbuhkan sikap toleransi siswa tidak bisa lepas dari penjelasan dalam Undang-undang Sistem Pendidikan Nasional No.20 pasal 4 tahun 2003 memuat pendidikan berbasis toleransi, bahwa pendidikan itu didasarkan pada sikap hormat terhadap martabat manusia, hati nurani dan keyakinan serta keikhlasan sesama tanpa melihat agama, suku, golongan, ideologi, atau pandangan hidup. Dengan adanya pembelajaran ini sikap toleransi siswa menjadi cara alternative untuk meningkatkan pemahaman siswa untuk menghargai kemultikulturan masyarakat Indonesia.The shift in students' tolerance attitude is influenced by the less than optimal strengthening of civic education learning, limited learning media so that the delivery of material is not delivered completely. The purpose of this paper is to describe the importance of learning college ball to foster student tolerance. The research method in this study is a qualitative research using a descriptive approach and literature study. Collecting data using literature study data (used to review scientific articles about college ball learning, tolerance attitude), document analysis (used to analyze education policies, papers, research results and scientific articles related to college ball learning and tolerance). Data analysis used descriptive analysis. The results of the study indicate that it is important to learn college ball to foster student tolerance by using the principles of open learning, group learning, and learning to play games. To foster an attitude of tolerance in students, it cannot be separated from the explanation in the National Education System Law No. 20 article 4 of 2003 which contains tolerance-based education, that education is based on respect for human dignity, conscience and beliefs and sincerity of others regardless of religion. , ethnicity, class, ideology, or way of life. With this learning, students' tolerance attitude becomes an alternative way to increase students' understanding to appreciate the multiculturalism of Indonesian society.
Морфологічне вивчення ґрунтоутворювальних процесів під лісовими насадженнями Криворіжжя
Authors: Ющук Євген Давидович
Published: April 2022

Розглянуто, що при видобутку залізної руди степові природні ландшафти порушуються. Створюються техногенні ландшафти, що погіршують санітарний стан навколишнього середовища.
Інтродуценти як компонент спонтанної дендрофлори девастованих земель
Authors: Савосько Василь Миколайович , Бєлик Юлія Віліївна , Лихолат Юрій Васильович
Published: April 2022

Мета роботи – з’ясувати місце інтродукованих видів у спонтанній дендрофлорі девастованих землях Криворіжжя. Досліджуючи роль інтродукованих видів у спонтанній дендрофлорі девастованих земель Криворіжжя, прийшли до висновку, що серед деревно-чагарникової флори переважають аборигенні види. Також спостерігається інтенсивне самовідновлення інтродукованих, потенційно інвазивних видів рослин, таких як клен ясенелистий (Acer negundo L.), маслинка вузьколиста (Elaeagnus angustifolia L.), садова iрга звичайна (Amelanchier ovalis Medik.), верба ламка (Salix flagilis L.) та робiнiя звичайна (Robinia pseudoacacia L.). Перспективними теоретичними та практичними дослідженнями є встановлення продуктивності, життєздатності та успішності деревних рослин на девастованих землях.
Із спостережень над семантико-граматичними особливостями лексичного повтору у функції присудка
Authors: Бондаренко Н. Г.
Published: April 2022

Досліджено конструкції з лексичним повтором, що висвітлюють різні аспекти цього мовного явища. Акцентовано особливу увагу на семантико-граматичних особливостях лексичного повтору у функції присудка.
Про своєрідні функції фразеологізованих конструкцій на рівні надфразної єдності
Authors: Явір В. В.
Published: April 2022

Розглянуто речення фразеологізованої структури, що вживаються на тлі контекстуального обрамлення на рівні надфразної єдності чи мікротексту. Розкрито властиві їм своєрідні текстоутворюючі функції, пов'язані з особливостями семантики та досить виразними суб'єктно-модальними значеннями, що дає підстави зробити висновок про тісний зв'язок і своєрідний статус цих речень у структурі НФЄ і мікротексту.
The new historical politics and criticism of Jawaharlal Nehru and Indira Gandhi in contemporary Indian press
Authors: Solodkova Olga
Published: April 2022

To successfully modernize the country and mobilize Indian society and to eventually implement ambitious plans for economic development, Bharatiya Janata Party (BJP) sets itself the task of achieving national unity. The BJP in the face of its leader Narendra Modi is forced to conduct constant polemics with their main political opponent - the Indian National Congress. Having come to power in 2014, the BJP representatives use a number of management methods aimed at changing the historical memory of the peoples of India, which can be characterized as "historical politics". The authorities are trying to back up their actions to mobilize Indian society with a new historical rationale, using Hindutwa as a "new ideology".
A new official version of the past is being formed, history and historical mythology are actively used to solve political problems of the present. The historical memory of society undergoes transformation and becomes an arena for the struggle against a political enemy. In the Indian press, every memorable date, every historical event becomes the basis for broad discussion and polemics with its historical predecessors and political competitors. After coming to power, Bharatiya Janata Party constantly refers to recent historical events, considering them from a certain ideological angle. This controversy, which has spilled over into the pages of the Indian press, allows us to talk about the BJP pursuing a new historical policy aimed at creating comfortable interpretations of controversial historical events for itself.
Japanese youth in the COVID-19 era
Authors: Zhilina Larisa V.
Published: April 2022

In Japan economic and health impacts of the COVID-19 pandemic have been asymmetric across age groups. Japan’s current wave of coronavirus infections has mostly affected its younger generations, reflecting both the efficacy of its vaccination program among the elderly and the pitfalls of a slow rollout that still hasn’t reached most of the youth population. And although now COVID-19 vaccines are available in Japan, it is very important to understand whether young Japanese are willing to be vaccinated against COVID-19, as this can have large consequences for the success of the vaccination program in the country all in all and this can cause potentially large as Japanese nation health and Japanese economic consequences.
Moreover, the surveys on Japanese citizens’ behavioral changes and preparedness against COVID-19 conducted by Japanese researchers in 2021 revealed that being younger was among the factors associated with reluctance to follow COVID-19 prevention measures. Despite a gradual lifting of confinement measures across Japan recently, changes in everyday behavior of Japanese citizen will still be crucial in the coming months to avoid new waves of infections. In this connection, building trust to government’ actions (taken COVID-19 pandemic fight measures) among the young people remains crucial.
Based on carried out in Japan 2021 surveys’ findings, the author highlights the key challenges arisen in the proses of vaccination, Japanese governance responses to build back better this situation for all generations of the country and possible ways for addressing new challenges.
Volume doubling time and radiomic features predict tumor behavior of screen-detected lung cancers
Authors: Pérez-Morales Jaileene , Lu Hong , Mu Wei , Tunali Ilke , Kutuk Tugce , Eschrich Steven A. , Balagurunathan Yoganand , Gillies Robert J. , Schabath Matthew B.
Published: April 2022

BACKGROUND: Image-based biomarkers could have translational implications by characterizing tumor behavior of lung cancers diagnosed during lung cancer screening. In this study, peritumoral and intratumoral radiomics and volume doubling time (VDT) were used to identify high-risk subsets of lung patients diagnosed in lung cancer screening that are associated with poor survival outcomes. METHODS: Data and images were acquired from the National Lung Screening Trial. VDT was calculated between two consequent screening intervals approximately 1 year apart; peritumoral and intratumoral radiomics were extracted from the baseline screen. Overall survival (OS) was the main endpoint. Classification and Regression Tree analyses identified the most predictive covariates to classify patient outcomes. RESULTS: Decision tree analysis stratified patients into three risk-groups (low, intermediate, and high) based on VDT and one radiomic feature (compactness). High-risk patients had extremely poor survival outcomes (hazard ratio [HR] = 8.15; 25% 5-year OS) versus low-risk patients (HR = 1.00; 83.3% 5-year OS). Among early-stage lung cancers, high-risk patients had poor survival outcomes (HR = 9.07; 44.4% 5-year OS) versus the low-risk group (HR = 1.00; 90.9% 5-year OS). For VDT, the decision tree analysis identified a novel cut-point of 279 days and using this cut-point VDT alone discriminated between aggressive (HR = 4.18; 45% 5-year OS) versus indolent/low-risk cancers (HR = 1.00; 82.8% 5-year OS). CONCLUSION: We utilized peritumoral and intratumoral radiomic features and VDT to generate a model that identify a high-risk group of screen-detected lung cancers associated with poor survival outcomes. These vulnerable subset of screen-detected lung cancers may be candidates for more aggressive surveillance/follow-up and treatment, such as adjuvant therapy.