bluuebunny/crossref_metadata_2025 huggingface dataset:
Impact of Brewers’ Spent Grain-Containing Biscuit on Postprandial Glycaemic Response in Individuals with Metabolic Syndrome: A Crossover Randomised Controlled Trial
Authors: Xu Yujing , Leong Zi Ning , Zhang Weijia , Jin Xinrui , Kong Jia Wen , Chan Gregory Chung Tsing , Kim Jung Eun
Published: March 2024

Brewers’ spent grain (BSG) is a fibre and protein-rich by-product of beer-brewing. Fermenting BSG with Rhizopus oligosporus can further increase its content of soluble fibre, protein and certain antioxidants. Since nutrients rich in BSG can improve postprandial glycaemic response, this study assessed the postprandial glucose response (PPGR) and postprandial insulin response (PPIR) controlling effect of consuming 30% wheat flour substituted biscuits with autoclaved BSG (ABSG) or fermented BSG (FBSG) in individuals with metabolic syndrome (MetS). The effect on postprandial lipid panel, breath hydrogen (H2) and methane (CH4) concentration and subjective appetite response was also examined. Fifteen subjects with MetS participated in this crossover randomised controlled trial, and blood was collected at 9 time-points for 4 h after consumption of control biscuits (Control), ABSG and FBSG. A significant interaction effect was observed (Pinteraction = 0.013) for the glucose time-points concentration. At 180 min, the glucose concentration was lowered after the consumption of ABSG (p = 0.010) and FBSG (p = 0.012) compared to the Control. Moreover, the FBSG resulted in a significantly lower glucose incremental area under curve (iAUC) compared to the Control (p = 0.028). Insulin level was also lowered at 180 min after the ABSG (p = 0.010) and FBSG (p = 0.051) consumption compared to the Control. However, no difference was noted for postprandial lipid panel, breath H2 and CH4 concentration and subjective appetite response. In conclusion, the consumption of BSG-incorporated biscuits can attenuate PPGR, and fermented BSG incorporation conferred a further PPGR controlling benefit.
A Review of Advances in Bioanalytical Methods for the Detection and Quantification of Olanzapine and Its Metabolites in Complex Biological Matrices
Authors: Czyż Anna , Zakrzewska-Sito Alicja , Kuczyńska Julita
Published: March 2024

Schizophrenia is a serious mental disorder that significantly affects the social and professional life of patients, causing distortion of reality and loss of identity and cognitive abilities. Psychopharmacological treatment is an integral part of modern psychiatry, and the introduction of new “atypical” antipsychotic drugs has brought significant progress in the treatment of this disorder. One of these drugs is olanzapine, which has an effective effect on the productive symptoms of schizophrenia while having an almost minimal potential to cause extrapyramidal syndrome. However, its effectiveness is confronted with frequent side effects, referred to as “metabolic disorders”. Therefore, to ensure the effectiveness of treatment and to minimize the side effects caused by olanzapine, it is recommended to monitor the drug level during therapy. This article reviews the bioanalytical methodologies that enable efficient extraction and sensitive analysis of olanzapine. We considered the advantages and disadvantages of different sample pretreatment methods, including traditional and novel strategies. The analytical conditions required for the separation and detection of olanzapine and its metabolites were analyzed using chromatographic methods combined with various detectors.
Optimization of the Production Process of Clinical-Grade Human Salivary Gland Organoid-Derived Cell Therapy for the Treatment of Radiation-Induced Xerostomia in Head and Neck Cancer
Authors: Zanten Jacoba van , Jorritsma-Smit Annelies , Westra Hans , Baanstra Mirjam , Bruin-Jellema Anne de , Allersma Derk , Gareb Bahez , Coppes Rob P.
Published: March 2024

Head and neck cancer is a common cancer worldwide. Radiotherapy has an essential role in the treatment of head and neck cancers. After irradiation, early effects of reduced saliva flow and hampered water secretion are seen, along with cell loss and a decline in amylase production. Currently, there is no curative treatment for radiation-induced hyposalivation/xerostomia. This study aimed to develop and optimize a validated manufacturing process for salivary gland organoid cells containing stem/progenitor cells using salivary gland patient biopsies as a starting material. The manufacturing process should comply with GMP requirements to ensure clinical applicability. A laboratory-scale process was further developed into a good manufacturing practice (GMP) process. Clinical-grade batches complying with set acceptance and stability criteria were manufactured. The results showed that the manufactured salivary gland-derived cells were able to self-renew, differentiate, and show functionality. This study describes the optimization of an innovative and promising novel cell-based therapy.
Comparative Transcriptome Analysis Reveals Inhibitory Roles of Strigolactone in Axillary Bud Outgrowth in Ratoon Rice
Authors: Ku Wenzhen , Su Yi , Peng Xiaoyun , Wang Ruozhong , Li Haiou , Xiao Langtao
Published: March 2024

Axillary bud outgrowth, a key factor in ratoon rice yield formation, is regulated by several phytohormone signals. The regulatory mechanism of key genes underlying ratoon buds in response to phytohormones in ratoon rice has been less reported. In this study, GR24 (a strigolactone analogue) was used to analyze the ratooning characteristics in rice cultivar Huanghuazhan (HHZ). Results show that the elongation of the axillary buds in the first seasonal rice was significantly inhibited and the ratoon rate was reduced at most by up to 40% with GR24 treatment. Compared with the control, a significant reduction in the content of auxin and cytokinin in the second bud from the upper spike could be detected after GR24 treatment, especially 3 days after treatment. Transcriptome analysis suggested that there were at least 742 and 2877 differentially expressed genes (DEGs) within 6 h of GR24 treatment and 12 h of GR24 treatment, respectively. Further bioinformatics analysis revealed that GR24 treatment had a significant effect on the homeostasis and signal transduction of cytokinin and auxin. It is noteworthy that the gene expression levels of OsCKX1, OsCKX2, OsGH3.6, and OsGH3.8, which are involved in cytokinin or auxin metabolism, were enhanced by the 12 h GR24 treatment. Taken overall, this study showed the gene regulatory network of auxin and cytokinin homeostasis to be regulated by strigolactone in the axillary bud outgrowth of ratoon rice, which highlights the importance of these biological pathways in the regulation of axillary bud outgrowth in ratoon rice and would provide theoretical support for the molecular breeding of ratoon rice.
DEAD-Box RNA Helicase Family in Physic Nut (Jatropha curcas L.): Structural Characterization and Response to Salinity
Authors: da Silva Rahisa Helena , Silva Manassés Daniel da , Ferreira-Neto José Ribamar Costa , Souza Bruna de Brito , de Araújo Francielly Negreiros , Oliveira Elvia Jéssica da Silva , Benko-Iseppon Ana Maria , da Costa Antonio Félix , Kido Éderson Akio
Published: March 2024

Helicases, motor proteins present in both prokaryotes and eukaryotes, play a direct role in various steps of RNA metabolism. Specifically, SF2 RNA helicases, a subset of the DEAD-box family, are essential players in plant developmental processes and responses to biotic and abiotic stresses. Despite this, information on this family in the physic nut (Jatropha curcas L.) remains limited, spanning from structural patterns to stress responses. We identified 79 genes encoding DEAD-box RNA helicases (JcDHX) in the J. curcas genome. These genes were further categorized into three subfamilies: DEAD (42 genes), DEAH (30 genes), and DExH/D (seven genes). Characterization of the encoded proteins revealed a remarkable diversity, with observed patterns in domains, motifs, and exon–intron structures suggesting that the DEAH and DExH/D subfamilies in J. curcas likely contribute to the overall versatility of the family. Three-dimensional modeling of the candidates showed characteristic hallmarks, highlighting the expected functional performance of these enzymes. The promoter regions of the JcDHX genes revealed potential cis-elements such as Dof-type, BBR-BPC, and AP2-ERF, indicating their potential involvement in the response to abiotic stresses. Analysis of RNA-Seq data from the roots of physic nut accessions exposed to 150 mM of NaCl for 3 h showed most of the JcDHX candidates repressed. The protein–protein interaction network indicated that JcDHX proteins occupy central positions, connecting events associated with RNA metabolism. Quantitative PCR analysis validated the expression of nine DEAD-box RNA helicase transcripts, showing significant associations with key components of the stress response, including RNA turnover, ribosome biogenesis, DNA repair, clathrin-mediated vesicular transport, phosphatidyl 3,5-inositol synthesis, and mitochondrial translation. Furthermore, the induced expression of one transcript (JcDHX44) was confirmed, suggesting that it is a potential candidate for future functional analyses to better understand its role in salinity stress tolerance. This study represents the first global report on the DEAD-box family of RNA helicases in physic nuts and displays structural characteristics compatible with their functions, likely serving as a critical component of the plant’s response pathways.
The Dynamic Changes of Brassica napus Seed Microbiota across the Entire Seed Life in the Field
Authors: Yao Yao , Liu Changxing , Zhang Yu , Lin Yang , Chen Tao , Xie Jiatao , Chang Haibin , Fu Yanping , Cheng Jiasen , Li Bo , Yu Xiao , Lyu Xueliang , Feng Yanbo , Bian Xuefeng , Jiang Daohong
Published: March 2024

The seed microbiota is an important component given by nature to plants, protecting seeds from damage by other organisms and abiotic stress. However, little is known about the dynamic changes and potential functions of the seed microbiota during seed development. In this study, we investigated the composition and potential functions of the seed microbiota of rapeseed (Brassica napus). A total of 2496 amplicon sequence variants (ASVs) belonging to 504 genera in 25 phyla were identified, and the seed microbiota of all sampling stages were divided into three groups. The microbiota of flower buds, young pods, and seeds at 20 days after flowering (daf) formed the first group; that of seeds at 30 daf, 40 daf and 50 daf formed the second group; that of mature seeds and parental seeds were clustered into the third group. The functions of seed microbiota were identified by using PICRUSt2, and it was found that the substance metabolism of seed microbiota was correlated with those of the seeds. Finally, sixty-one core ASVs, including several potential human pathogens, were identified, and a member of the seed core microbiota, Sphingomonas endophytica, was isolated from seeds and found to promote seedling growth and enhance resistance against Sclerotinia sclerotiorum, a major pathogen in rapeseed. Our findings provide a novel perspective for understanding the composition and functions of microbiota during seed development and may enhance the efficiency of mining beneficial seed microbes.
Exploring Vortex–Flame Interactions and Combustion Dynamics in Bluff Body-Stabilized Diffusion Flames: Effects of Incoming Flow Velocity and Oxygen Content
Authors: Chen Mingmin , Zhao Minwei , Wang Zhihao , Huang Xinbo , Zheng Hongtao , Deng Fuquan
Published: March 2024

An afterburner encounters two primary features: high incoming flow velocity and low oxygen concentration in the incoming airflow, which pose substantial challenges and contribute significantly to the deterioration of combustion performance. In order to research the influence of oxygen content on the dynamic combustion characteristics of the afterburner under various inlet velocities, the effect of oxygen content (14–23%) on the field structure of reacting bluff body flow, flame morphology, temperature pulsation, and pressure pulsation of the afterburner at different incoming flow velocities (0.1–0.2 Ma) was investigated in this study by using a large eddy simulation method. The results show that two different instability features, BVK instability and KH instability, are observed in the separated shear layer and wake, and are influenced by changes in the O2 mass fraction and Mach number. The oxygen content and velocity affected the oscillation amplitude of the downstream flow. As the O2 mass fraction decreases, the flame oscillation amplitude increases, the OH concentration in the combustion chamber decreases, and the flame temperature decreases. Additionally, the amplitude of the temperature pulsation in the bluff body flame was primarily influenced by the temperature intensity of the flame and BVK instability. Moreover, the pressure pulsation is predominantly affected by the dynamic characteristics of the flow field behind the bluff body. When the BVK instability dominated, the primary frequency of the pressure pulsation aligned with that of the temperature pulsation. Conversely, under the dominance of the KH instability, the temperature pulsation did not exhibit a distinct main frequency. At present, the influence of oxygen content and incoming flow rate on the combustion performance of the combustion chamber is not clear. The study of the effect of oxygen content on the combustion characteristics of the combustion chamber at different incoming flow rates provides a reference for improving the performance of the combustion chamber and enhancing the combustion stability.
Christian Neoplatonism and Deep Incarnation: Nicholas of Cusa and Giordano Bruno as Inspirations for Contemporary Ecotheology
Authors: Eaton Matthew
Published: March 2024

In response to the specter of looming anthropogenic ecological catastrophe, many Christian thinkers have begun to rethink the God/world relationship and reimagine the ontic cleavage between divinity and creation. The idea of “deep incarnation”, which expands the scope of divine incarnation in an attempt to draw God and creation into closer relation, is a prevalent framework for such reimagination. Two historic, underutilized thinkers that might help deep incarnation theologians expand their own theologies and make sense of the conceptual and ethical differences among them are Neo-Platonist philosopher–theologians Nicholas of Cusa and Giordano Bruno. Working within an ecofeminist framework, this article argues that while both Cusanus and Bruno provide significant philosophical grounds for contemporary ecotheologies of deep incarnation, a Brunist perspective is preferable because of its more expansive anthropology and its more inclusive understanding of divinity.
The Self and the Other: A Further Reflection on Buddhist–Christian Dialogue
Authors: Zhang Shiying
Published: March 2024

The dialogue between and comparative research into Christianity and Buddhism theoretically involve the issues of self and other. Faced with the cultural reality of religious diversity, theologies of religions provide four modes of dialogue through which Christianity can interface with religious others. The exploration of the infinite and transcendent traits of otherness in contemporary phenomenological philosophy, as well as the emphasis on differences in postmodern philosophy, contributes to maintaining a clear awareness of otherness and self-identity in the Buddhist–Christian dialogue. Following the dialogical path in comparative theology, which leads one out of oneself, into the other, and back into oneself, in experimental Buddhist-Christian dialogue activities, both Christianity and Buddhism figure as the self and the other. If they openly accept each other’s otherness and heterogeneity, view each other as mirrors, and criticize and reflect on themselves, then creative insights into themselves will ultimately be generated. Their selves will be rediscovered, and their understanding and expression will be updated. Reflecting on the Buddhist–Christian dialogue from four aspects, namely, ultimate realism, cosmology, ethics, and religious ideals, can eliminate some misunderstandings and deepen both parties’ understandings of themselves and others.
Seals as a Reflection of the Self-Confidence, Self-Image and Identity of the Teutonic Order
Authors: Kemmer Katharina
Published: March 2024

This article deals with the question of the extent to which the Teutonic Order, as a clerical order of knights founded during the Third Crusade, succeeded in expressing its self-confidence and identity by means of its seal. The “geographical” area of investigation extends to the bailiwicks of Franconia, Alsace–Burgundy, Lorraine, Austria, An der Etsch and in the mountains (South Tyrol) as well as the so-called Deutschmeistertum, whereby the terms mentioned do not necessarily correspond to the present-day areas of that designation. The time frame is within the Middle Ages. Due to the large number of surviving seals of the Teutonic Order, however, only a small insight from a larger study can be provided here. Selected seals of the Order’s various internal leadership strata are therefore presented, compared and examined to determine whether and to what extent they express a form of self-confidence and identity.
Clusterisation and Temporal Trends of Heat Flux by UAS Thermal Camera
Authors: Marotta Enrica , Peluso Rosario , Avino Rosario , Avvisati Gala , Bellucci Sessa Eliana , Belviso Pasquale , Caputo Teresa , Carandente Antonio , Cirillo Francesca , Pescione Romano Antonio
Published: March 2024

Analysis of a series of thermal mappings obtained by UAS flights on quiescent volcanoes requires some special techniques to be performed. The main challenge is represented by the difficulty of separating hot and cold pixels in areas where their temperatures are quite similar. This task is indeed much simpler, for example, for lava flows where the temperature differences between the hot lava and the cold soil is rather big. This paper shows various software developed in order to perform this extraction and calculate the trends over time of both the average temperature and the heat flux from the soil. This prototypal implementation used thermal flights performed over a time span of a few years on an area in the Campi Flegrei caldera in southern Italy. Standard image manipulation techniques were used to segmentate and clusterise each thermal mapping in order to reduce the thermal anomalies to some sets of simpler features characterised by their fundamental parameters. The temporal trends of some physical parameters (temperature, heat flux, etc.) were extracted from these sets, and we found interesting results necessary for correlations and for ongoing research with other parameters.
Evolution of Social Competencies in Sustainable Supply Chains
Authors: Foltynowicz Zenon , Łupicka-Fietz Anna , Jeszka Anna Maria , Kowalczyk Damian
Published: March 2024

In many sectors of the economy, the global changes brought about by COVID-19, the war in Ukraine and the ensuing economic crisis have challenged the hitherto used social competencies necessary to successfully manage companies in sustainable supply chains. The slogan of sustainability has now become a household word in the global economy. At the same time, the EU is moving from a 4.0 to a 5.0 economy, with increasing attention being paid to the soft competencies of future managers. This article aims to present the patterns of competencies in supply chains and to identify the relevance of specific social competencies for doing business in the face of the above challenges. The survey was conducted among selected experts from the healthcare industry, who were asked to identify the importance of social competencies. This choice was primarily motivated by certain characteristics of the industry. This work aims to determine which social competencies seem to be essential for future managers in sustainable supply chains and the transformation towards a 5.0 economy. The answer to this question is crucial for research and teaching centers aiming to educate future managers at the highest level of specific social competencies and skills in a business environment. Given the dynamic development of specific industries, it is reasonable to identify the needs in the areas of social skills.
Utilization of Inedible Parts of Aralia cordata with High-Content Chlorogenic Acid Cultivated in Tokyo
Authors: Matsuo Hirotaka , Kawakami Hitomi , Otsuki Yuka , Miyashita Chieto , Kawahara Nobuo , Fuchino Hiroyuki , Yoshimatsu Kayo
Published: March 2024

Aralia cordata is called “Udo” and is one of the famous herbaceous perennial plants found in Korea, China, and Japan. In Japan, aerial parts of A. cordata have been consumed. Furthermore, its rhizome and root are utilized as crude drugs known as “dokukatsu” and “wakyoukatsu”, respectively. A. cordata is cultivated as a vegetable in many places in Japan, and one of the production areas is Tokyo. A. cordata made in Tokyo is known as a high-quality “Udo” product (aerial part) using a unique cultivation method, known as “Udo muro”. “Udo muro” blocks light and maintains optimal temperature and humidity throughout the year, facilitating the soft cultivation of udo. However, the roots of A. cordata cultivated in Tokyo are all discarded. Thus, the utilization of the A. cordata root cultivated in Tokyo might lead to sustainability and income improvement for farmers. In this study, we investigated the effect of “Udo muro” with or without cultivation and drying temperature on chlorogenic acid (CA) contents in A. cordata root and compared it with A. cordata produced in other areas (“wakyoukatsu”) by a quantitative analysis of the CA content using high-performance liquid chromatography. The results indicate that the CA content of the roots of A. cordata grown in Tokyo was higher than those grown in other areas. Furthermore, the usefulness of A. cordata root was evaluated using inhibitory activity tests such as nitric oxide production and melanin production using Raw264.7 and B16F10 cell lines, respectively.
Seasonal Freezing Drives Spatiotemporal Dynamics of Dissolved Organic Matter (DOM) and Microbial Communities in Reclaimed Water-Recharged River
Authors: Zhao Jiaqi , Huo Yang , Zhang Zhiruo , Zhang Ying , Hou Zhenlai , Fan Wei , Geng Zhi , Huo Mingxin
Published: March 2024

Although reclaimed water (RW) has become a promising alternative source for alleviating water shortage in arid and semiarid regions, the ecological risks it poses to the receiving water bodies remain largely unknown. Dissolved organic matter (DOM) is crucial for affecting the quality of RW and strongly influences bacterial communities (BCs) in aquatic ecosystems. In this study, we aimed to unravel the role of DOM signatures on the spatiotemporal composition of microbial communities (MCs) in a seasonally ice-sealed urban river that had been chronically replenished by RW. We found that discharging RW resulted in elevated DOM levels in the receiving river. Notably, an increase of 10% in protein-like substances was revealed. The differences between compositional characteristics of DOM and the abundance of riverine BCs between freezing and non-freezing periods were revealed. In the freezing season, humic-like components, aromaticity, and hydrophobicity of DOM were more significant, and bacterial taxa such as Bacteriodetes and Flavobacterium were increased, while Proteobacteria was decreased. Similarly, co-occurrence network analysis revealed an enhanced interplay between DOM and BCs at the same time. However, Klebsiella pneumoniae markedly decreased during the ice-sealed period. These results suggest that variations in DOM characteristics have remarkable impacts on the dynamics of aquatic BCs, which points to the need for a DOM−oriented RW quality monitoring strategy.
Experimental Study on the Slip–Stick Vibration of Plane Gate
Authors: Wang Yanzhao , Xu Guobin , Liu Zhicheng , Yang Deming
Published: March 2024

The slip–stick vibration intensity of a plane gate is usually large, which often brings serious safety risks to itself and the auxiliary structure. The slip–stick vibration of a plane gate is investigated using an experimental model test. The test conditions mainly focus on the gate-closing and gate-opening processes in transient flow. Based on the results, comparison diagrams of the slip–stick vibration response versus the external fluid excitation are constructed. The intensity and period of the slip–stick vibration both gradually increase with the opening degree of the plane gate decreasing. The frequency of slip–stick vibration is consistent with the natural frequency of the equivalent system, indicating that the slip–stick vibration is a nonlinear self-excited vibration. The slip–stick vibration and fluid excitation acting on the plane gate have a significant difference in response intensity and dominant frequency. In addition, a difference in gate support material can have a significant effect on the slip–stick vibration intensity. Therefore, the friction factor between gate support and track, rather than the fluid excitation, is the direct cause of slip–stick vibration, which can further prove that the slip–stick vibration is a friction-induced vibration caused by the gate’s active motion, enriching the theory of the gate’s vibration.
Visual Odometry Based on Improved Oriented Features from Accelerated Segment Test and Rotated Binary Robust Independent Elementary Features
Authors: Wu Di , Ma Zhihao , Xu Weiping , He Haifeng , Li Zhenlin
Published: March 2024

To address the problem of system instability during vehicle low-speed driving, we propose improving the visual odometer using ORB (Oriented FAST and Rotated BRIEF) features. The homogeneity of ORB features leads to poor corner point properties of some feature points. When the environmental texture lacks richness, it leads to poor matching performance and low matching accuracy of the feature points. We solve the problem of the corner point properties of feature points using weight calculation for regions with different textures. When the vehicle speed is too low, the continuous frames captured by the camera will overlap significantly, causing large fluctuations in the system error. We use motion model estimation to solve this problem. Meanwhile, experimental validation using the KITTI dataset achieves good results.
La Cour africaine des droits de l’homme et des peuples à la croisée des chemins
Authors: Burgorgue-Larsen Laurence
Published: March 2024

La Cour africaine des droits de l’homme et des peuples est à la croisée des chemins. D’un côté, son office se déroule dans un contexte continental marqué par une recrudescence des conflits où certaines grandes puissances se font la guerre indirectement et où les attaques djihadistes, au coeur du Sahel, terrorisent les populations. Ce contexte géopolitique n’encourage guère les Etats membres de l’UA, déjà historiquement réticents au mécanisme africain de garantie, à s’engager activement afin de soutenir les compétences

de la Commission et de la Cour africaines. Bien au contraire, leurs politiques juridiques extérieures se déploient, en général, pour affaiblir et contrôler leurs actions. D’un autre côté, l’oeuvre prétorienne de la Cour ne cesse de s’enrichir. Qu’il s’agisse de la protection des enfants, des femmes, des communautés autochtones, des détenus ; de l’édification de critères relatifs aux garanties du procès équitable ou encore de la défense de la démocratie, la jurisprudence de la Cour est, comme tel, incontestablement à la hauteur des questions qui assaillent le continent africain. La «Cour d’Arusha » est donc, incontestablement, à la croisée des chemins : vulnérable et puissante à la fois. Pour combien de temps encore cette ambivalence perdurera-t-elle ? Nul ne peut le prédire.
La bataille de la 5G et le droit international
Authors: Achilleas Philippe
Published: March 2024

Résumé : La sécurité des systèmes d’information, désormais considérée comme une question de souveraineté, a pris une soudaine dimension politique avec l’arrivée de la cinquième génération de téléphonie mobile (5G) dont le déploiement a commencé en 2020, selon le calendrier fixé par l’UIT. La prise de conscience des enjeux de cybersécurité est liée à la montée en puissance rapide de la Chine et de son fleuron technologique Huawei dans l’écosystème numérique. Les États-Unis, déjà engagés dans un bras de fer commercial avec Pékin, ont pris une série de mesures visant à limiter la dynamique technologique de la Chine. Depuis, plusieurs pays ont adopté des mesures de contrôle et de restriction visant les équipements chinois. L’objectif est double : prévenir les atteintes à la sécurité nationale par le biais des infrastructures de télécommunications et soutenir l’émergence d’écosystèmes 5G souverains. La Chine inquiète, car elle ne partage pas les valeurs des États-Unis et de l’Union européenne en matière de libertés numériques. Pourtant, aucune preuve ne permet clairement de corroborer les accusations d’espionnage numérique proférées à l’encontre de Pékin. Dès lors, cette contribution vise à déterminer si la 5G, et plus particulièrement la position dominante des équipementiers chinois, représente une menace pour les autres États et pour les personnes afin de mieux apprécier la portée et la licéité des mesures de protection adoptées par les gouvernements.
Anatomia ar: uma abordagem interativa ao corpo humano com um software de Realidade Aumentada
Authors: Canto Pâmela Vitória Lima , Pinto Yago Vitório Colares , Miranda Francisco Otávio
Published: March 2024

A transformação educacional se dá por meio da integração de novas tecnologias. Nesse sentido, a partir da Realidade Aumentada (RA) no ensino de ciências, destacamos a aplicação "ANATOMIA AR”, que proporciona uma experiência interativa e envolvente ao explorar os sistemas muscular e esquelético do corpo humano. A RA promove uma compreensão aprofundada da anatomia, enquanto a interatividade dinâmica estimula o engajamento dos alunos. O artigo inclui um recurso complementar, o livreto "Corpo Humano em 3D", enriquecendo a exploração anatômica. Os resultados demonstram a eficácia da RA na criação de uma experiência educacional rica em detalhes. O projeto representa um avanço na integração tecnológica e destaca a importância de abordagens inovadoras para enriquecer o aprendizado.
Jóvenes hiperconectados: producción y consumo de contenidos en el entorno comunicacional contemporáneo
Authors: Guardia Crespo Marcelo
Published: March 2024

La academia está transitando hacia enfoques más complejos que descentran los medios de comunicación y las redes sociales como únicos generadores de consciencia. La investigación sobre jóvenes está desafiada a comprender los procesos culturales a partir de la perspectiva de los actores. Esta reflexión revisa literatura científica e identifica las variables: identidad, participación, uso de redes y desinformación; como relevantes. Las mismas se contrastan con los resultados de la investigación de campo realizada sobre jóvenes, en áreas urbanas y rurales, concluyendo que los jóvenes están desarrollando estrategias de sobrevivencia material y simbólica en función de intereses concretos e interpelan al mundo oficial adulto, debido a que éste pone en riesgo el futuro, en todos sus componentes sociales.
Pseudociencia,conspiración, enfasis individualista: discurso negacionista en Twitter ante vacunación por Covid-19
Authors: Gartenlaub Andrea , Arenas Rodolfo , Alfaro Andrea
Published: March 2024

Frente a la pandemia por la COVID-19 y ante la resistencia al inicio de las jornadas de vacunación realizadas en Chile en 2021, se buscó describir la tematización de los discursos negacionistas. Para ello se recopilaron 15.530 tweets que se referían a estos temas y, tras descartar duplicados y temas tangenciales, se analizó un corpus de 3.652 mensajes con una lectura categorial basada en la teoría fundamentada. Los resultados muestran la existencia de dos grandes campos negacionistas: los argumentos pseudocientíficos -desconfianza respecto de la vacuna, sospechas frente a la política y defensa de derechos individuales- y argumentos conspiranoicos -experimentación, ocultamiento de decisiones y acciones de la elite-. Este trabajo concluye que el individualismo (descreencia, sospecha, elucubraciones, ideología) vertebra el negacionismo vacunal chileno.
Marketing digital como herramienta para ventas en plataformas en los emprendedores de tumbes, 2020
Authors: Mena Farfan Karl Vladimir , Mendoza Saldaña Claudia , Santos Cornejo Lynley Mylena
Published: March 2024

El objetivo principal de esta investigación es “Determinar la influencia del marketing digital en las ventas en RR.SS. entre los emprendedores de Tumbes en el año 2020”. Respecto a la metodología, el tipo es correlacional explicativa. El enfoque es cuantitativo con diseño no experimental y corte transversal. Se emplea como instrumento un cuestionario dirigido a la muestra que está conformada por 60 emprendedores. Los resultados evidencian que el grado de influencia es “bueno”, con un 87% respecto a ventas, mientras el 10% lo clasifica como “regular”. Además, tan solo una frecuencia de 3 emprendedores lo considera como “excelente”. Se concluye que sí existe influencia del marketing digital en las ventas en RR.SS. entre los empresarios tumbes.
institucionalización editorial de la historia patria en Colombia, 1900-1918
Authors: Samacá Alonso Gabriel David
Published: March 2024

El artículo busca reconstruir la concepción y puesta en marcha de la Biblioteca de Historia Nacional como parte del proceso de institucionalización que experimentó la escritura de la historia en Colombia en las dos primeras décadas del siglo XX. Esta empresa comenzó como una iniciativa particular para convertirse en uno de los proyectos fundamentales de la Academia Nacional de Historia. Mediante la compilación, preparación y publicación de fuentes documentales, así como la difusión de investigaciones originales, se sentaron las bases para la práctica científica de la historia. A partir de algunas herramientas de la historia de la edición, sostenemos que la formalización del saber histórico en este país norandino fue posible gracias a la labor editorial que emprendió el Estado para afianzar una visión del pasado centrada en la construcción del orden republicano por encima de las diferencias partidistas. La historia oficial elaborada desde la Academia no estuvo exenta de las debilidades administrativas, limitaciones económicas y avatares propios de un Estado en tiempos de postguerra. El trabajo se basa en el estudio de la correspondencia institucional, documentación personal de uno de los principales editores de la Biblioteca, los volúmenes publicados en las dos primeras décadas y publicaciones seriadas.
Variaciones sobre la metáfora del “Continente Enfermo”. El caso de César Zumeta: “El hierro fortifica. Armémonos”
Authors: Granados Aimer
Published: March 2024

Este trabajo involucra dos niveles de estudio. En el primero de ellos se tipifica analíticamente lo que el escritor venezolano César Zumeta representó en términos de un “escritor politizado” y de un “intelectual polivalente”. Estas dos categorías involucran la siguiente pregunta ¿Qué fue un intelectual latinoamericano durante el cambio del siglo XIX al XX?  A partir de tipificar a Zumeta dentro de ciertas figuras del intelectual, paralelamente se dan algunas puntadas críticas al problema de las generaciones con el fin de posicionar a Zumeta dentro de la generación latinoamericana del 900. En la segunda parte del trabajo se aborda el opúsculo de Zumeta titulado El Continente Enfermo, con el fin de contextualizar este escrito dentro de una serie de ensayos escritos por intelectuales latinoamericanos que, a la vuelta del siglo XIX al XX, reflexionaron, escribieron y compartieron un horizonte de expectativas nada positivo para los países de la región. De allí que hubieran acuñado la metáfora del “continente enfermo”. Sin embargo, no fue ésta una noción unívoca, todo lo contrario, como lo muestra la reflexión que sobre las “enfermedades” del continente realizó Zumeta.
Presentación del dossier "América Latina: la metáfora del “Continente Enfermo”"
Authors: Granados Aimer
Published: March 2024

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Semblanza histórica del cronista peruano fray Diego de Córdova y Salinas (Siglo XVII)
Authors: Gento Sanz Benjamín
Published: March 2024

Uno de los franciscanos más distinguidos e ilustres en el mundo de las letras en el siglo XVII, en Sudamérica, fue el celebrado Cronista Fray DiegodeCórdovay Salinas. Su pluma en ocasiones churrigueresca y ágil, fecunda y florida, aunque a veces algún tanto pesada y embarazosa, le coloca en un sitial preponderante en el templete de los escritores americanos, y sus Crónicas y escritos, son y serán una fuente de cristalinas aguas de la historiografía y de la consulta documental.
Los caminos de Santa Cruz de la Sierra en el siglo XVI
Authors: Vazquez Machicado Humberto
Published: March 2024

Los caminos, o sean las rutas de comunicación de un lugar con otro, son muchísimo más antiguos que la humanidad. Las quiebras de las montañas, las hendiduras en los llanos, servían de caminos a los grandes o pequeños torrentes que se desplazaban en uno y otro sentido y que hoy día constituyen ríos, arroyos, quebradas, etc. Aquellos "caminos que andan", como se ha dado en llamarles, fueron pues los primeros que conoció el planeta, mientras apenas comenzaba a aparecer la vida sobre la superficie de la tierra.
La historia intelectual de Hispanoamérica en el siglo XVIII
Authors: Whitaker Arthur
Published: March 2024

El foco del presente ensayo historiográfico, necesariamente breve, es la Ilustración del siglo XVIII. La Ilustración fue, en este siglo, el tema central de los pensadores hispanoamericanos más importantes y de los pensadores extranjeros que dedicaron atención a Hispanoamérica; y, desde entonces, las distintas maneras de considerar la Ilustración han influido radicalmente sobre la interpretación de la historia intelectual de Hispanoamérica en el siglo XVIII.
Un intento de evangelizar a los indios Araucas en 1553
Authors: Gómez Canedo Lino
Published: March 2024

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Las actas de Independencia de América (Rafael Heliodoro Valle)
Authors: Millares Carlo Agustin
Published: March 2024

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GONZALO BULNES, Guerra del Pacifico
Authors: Silva Castro Raúl
Published: March 2024

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Encyclopédie de l'Amérique Latine, Politique, économique, culturelle
Authors: Pierre Berthe Jean
Published: March 2024

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ILUSTRE Colegio Notarial de Madrid. La vida privada española en el Protocolo notarial. Selección de documentos de los siglos XVI, XVII y XVIII del Archivo Notarial de Madrid, publicada con ocasión del II Congreso Internacional del Notariado Latino.
Authors: Millares Carlo Agustin
Published: March 2024

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IZQUIERDO, JOSÉ JOAQUÍN: Montaña y los orígenes del movimiento social y científico de México, México, 1955, Ediciones Ciencia, prólogo del Dr. Henry E. Sigerist, XVI +442 p., 57 ils.
Authors: D`Ardois G. Solominos
Published: March 2024

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JIMÉNEZ RUEDA, JULIO: Historia Jurídica de la Universidad de México, México, Facultad de Filosofía y Letras, 1955, 262 p.
Authors: Hernández Millares Jorge
Published: March 2024

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RODRIGUES, JOSÉ HONORIO: A Pesquisa histórica no Brasil. Sua evolução e problemas atuais. Rio de Janeiro, Departamento de Imprensa Nacional, 1952. 286 (2) pp. (Ministerio da Educação e Saúde.
Authors: Mantecón José Ignacio
Published: March 2024

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SBARRA, NOEL H.: Historia del alambrado en Argentina. Buenos Aires, Editorial Raigal, 1955, 85pp.
Authors: Piccirilli Ricardo
Published: March 2024

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GREVE, ERNESTO: El conquistador Francisco de Aguirre. Comentarios y complementos al libro del Pbro. Luis Silva Lezaeta. Santiago de Chile, Fondo Histórico y Bibliográfico J.T. Medina, 1953, 204 pp.
Authors: Canedo Lino G.
Published: March 2024

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VARGAS UGARTE, RUBÉN, S. J.: La Carta a los españoles americanos de Don Juan Pablo Vizcardo y Guzmán. Lima, Editorial del CIMP, s. f. [1955], 131 pp., 24.7 cm., ils.
Authors: Bravo Ugarte José
Published: March 2024

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Arteryel Switch Operasyonlarında Aortopulmoner Çap Uyumsuzluğunu Gidermek İçin Nonkoroner Sinüs Plikasyonu
Authors: Doyurgan Onur , İrdem Ahmet Kuddusi , Kılıç Yiğit , Özdemir Fatih , Balık Hasan , Akdeniz Osman
Published: March 2024

Öz
Amaç: Ciddi aortopulmoner çap uyumsuzluğu arteryel switch operasyonu sırasında karşılaşılan bir problemdir. Sinotubuler bileşke geometrisini bozarak postoperatif neoaortik kapak yetmezliğine neden olabilir. Bu çalışmada aortopulmoner çap uyumsuzluğunu gidermek için uyguladığımız cerrahi teknikleri ve bu prosedürün sonuçlarını inceledik. Materyal ve metod: Hastanemizde Aralık 2017-Mayıs 2023 tarihleri arasında büyük arter transpozisyonu (BAT) tanısı ile opere edilen hastalar arasından pulmoner arter / aort çap uyuşmazlığını gidermeye yönelik cerrahi prosedür uygulanan hastalar çalışmaya alındı. Hastalar nonkoroner sinüs plikasyonu yapılanlar ve diğer teknikler uygulananlar olarak iki gruba ayrıldı. Pulmoner arter / aort çap uyuşmazlığı sinotubuler bileşkede pulmoner arter çapının aorta çapının iki katından fazla olması olarak tanımlandı. Bulgular: Arteryel switch operasyonu yapılan 127 hastadan 23’ünde (%18,1) aortopulmoner çap uyumsuzluğu mevcuttu. Aortopulmoner çap uyumsuzluğu olan hastaların 15’ine (%65,2) nonkoroner sinüs plikasyonu, 5’ine (%21,7) aort anterior duvarına longitudinal insizyon ile genişletme, 2’sine (%8,7) pulmoner arterden doku rezeksiyonu ve 1’ine (%4,4) aort anterior duvarda otolog perikard yama ile genişletme yapıldı. Hastaların 15’i erkek, ortanca yaşı 14 gün ve ortanca ağırlığı 3,3 kg olarak saptandı. Hastaların 9’u basit BAT iken 10 hastada büyük arter transpozisyonuna ventriküler septal defekt, 4 hastada Taussig-Bing anomalisi, 4 hastada aortik ark patolojisi eşlik ediyordu. İki hasta sol ventrikül disfonksiyonu nedeniyle ve bir hasta sepsis nedeniyle yaşamını yitirdi. Gruplar arasında perioperatif veriler açısından anlamlı farklılık bulunmadı. Takipte hafif neoaortik kapak yetmezliği oranı nonkoroner sinüs plikasyonu yapılan hastalarda %33,3 (n=5), diğer tekniklerin uygulandığı hastalarda %37,5 (n=3) bulundu. Hiçbir hastada neoaortik kapak darlığı veya orta/ciddi neoaortik kapak yetmezliği saptanmadı. Sonuç: Nonkoroner sinüs plikasyonu arteryel switch operasyonlarında aortopulmoner çap uyumsuzluğunu gidermeye yönelik basit, düşük riskli ve uygulaması kolay bir prosedürdür. Bu teknik kullanılarak aort ve pulmoner arter arasındaki asimetri ortadan kaldırılabilir ve daha doğal bir anatomi oluşturulması sağlanabilir.
Maternal Aneminin Perinatal Sonuçlara Etkisinin Değerlendirilmesi
Authors: Barut Mert Ulaş , Adak İbrahim Halil , Sak Sibel
Published: March 2024

Amaç: Çalışmamızın amacı Harran Üniversitesi Tıp Fakültesi Kadın Hastalıkları ve Doğum kliniğinde son 1 yılda yatan ve doğum yapan gebelerde Maternal Aneminin Perinatal Sonuçlara etkisinin değerlendirilmesidir.

Gereç ve Yöntemler: Çalışmaya 1 Ocak 2021 – 31 Aralık 2021 arasında Harran Üniversitesi Tıp Fakültesi Kadın Hastalıkları ve Doğum kliniğine yatan ve doğum yapan gebeler dahil edildi. Bu gebelerin bilgileri retrospektif olarak değerlendirildi. Çalışma grubu, doğum için başvuru esnasında hemog¬lobin düzeyi ile 3. trimesterda bakılmış hemoglobin düzeyi <11 g/dl olan gebelerden oluşturuldu. Kontrol grubu ise aynı tarih aralığında doğum yapan, doğumda ve 3. trimesterda hemoglobin düzeyi 11 g/dl ve üzerinde olan ve sistemik hastalığı olmayan gebeler tarafından oluşturuldu. Hastalar randomize seçildi. Gruplar obstetrik ve perinatal sonuçlar açısından karşılaştırıldı.
Bulgular: Bu araştırmaya 50 gebe çalışma grubu olarak ve 50 gebe de kontrol grubu olmak üzere toplam 100 gebe dahil edildi. Gruplar arasında düşük doğum ağırlığı, normal doğum ağırlığı, intrauterin gelişme kısıtlılığı oranları, bebeklerin 1. ve 5. dakika apgar skorları, yenidoğan servisine yatış oranları açısından istatistiksel olarak anlamlı bir farklılık saptanmadı (p>0,05). Anemik grupta preterm doğum, oranı istatistiksel olarak kontrol grubuyla anlamlı derecede yüksek bulundu. (%34 vs %14, p=0,020),

Sonuç: Çalışmamızda elde edilen verilere göre gebelerde Anemik grupta preterm doğum, oranı istatistiksel olarak kontrol grubundan anlamlı yüksek bulundu.
Lenguaje e inconsciente en Freud: representaciones de palabras y representaciones de cosas
Authors: Arrivé Michel , Vilela Izabel
Published: March 2024

Los psicoanalistas tienden a menudo a olvidar ¿o bien a ocultarlo? Corresponde a los lingüistas y a los semiotistas recordárselo: el lenguaje está en el centro de las preocupaciones de Freud. Es según un criterio semiológico que se efectúa la distinción freudiana entre inconsciente y preconsciente-consciente. El artículo de Michel Arrivé e Isabel Vilela sigue la historia de esta oposición fundante a lo largo de la reflexión freudiana. Consideran también las incidencias —complejas y paradójicas, pero particularmente instructivas para el semiotista— sobre el postulado lacaniano del “inconsciente estructurado como un lenguaje”.
La conversión de tocar en ver. Trompe-l’oeil y posicionamiento estratégico
Authors: Beyaert-Geslin Anne
Published: March 2024

El artículo trata de poner de manifiesto la axiología subyacente a la representación de las sensorialidades en el objeto que constituye un trompe-l’oeil. Se apoya en el ejemplo de la porcelana de Limoges para revelar la dificultad de la situación estratégica de ciertos materiales considerados como preciosos, los cuales, para renovar su imagen, se ven obligados a la degradación y representan valores comunes por medio de materiales nobles.
Cambios inducidos por contacto en el español de la sierra ecuatoriana: la simplificación de los sistemas pronominales (procesos de neutralización y elisión)
Authors: Palacios Alcaine Azucena
Published: March 2024

En esta investigación abordo los cambios que se documentan en los sistemas pronominales del español serrano ecuatoriano de Otavalo e Ibarra; en concreto, la simplificación del sistema pronominal, que se manifiesta en dos aspectos intrínsecamente relacionados: a) la simplificación de las formas pronominales mediante la neutralización de los rasgos de género y/o caso; y b) la elisión pronominal. Muestro, igualmente, que el rasgo [+/- animado] del referente juega un importante papel. Asimismo, señalo cómo estos cambios han sido favorecidos por el contacto con el quichua, lengua de bilingüismo histórico en la zona.
El cuerpo de la escritura
Authors: Rodríguez Vázquez Blanca Alberta
Published: March 2024

Este artículo es un acercamiento a la obra Migraciones de Gloria Gervitz (México 1943), cuya poesía se presenta como una suerte de deriva que va de una escritura del cuerpo al cuerpo mismo de la escritura. El cuerpo es no sólo un tema recurrente de esta poesía sino que la propia página que la alberga está configurada como un cuerpo que acompaña a aquél en sus inflexiones.El cuerpo exige ser tratado como superficie de inscripción, como página, y ésta —objeto pregnante— se vuelve una suerte de piel que se ofrece simultáneamente al ojo y a la mano. Una revisión diacrónica de las continuas reconfiguraciones que este extenso poema ha tenido en su historia, deja ver que ellas inciden no sólo en la fisonomía del poema, sino también en su significación. Esto es así porque, cualquiera que sea su modalidad, la escritura implica la modificación de una superficie cuando se produce la incisión. La acción de la mano sobre el soporte material convierte en lugar significante lo que hasta entonces era una simple extensión. Ese lugar es la página. El poema, por tanto, no se agota en lo que las palabras dicen, pues el lugar desde donde lo hacen contribuye al sentido. El espacio, en consecuencia, no se limita a su condición de soporte material porque, configurado en página, constituye ahora un espacio ya no sólo visible sino también legible. Y es en este momento de la inscripción que la voz del poema deviene cuerpo visible, cuerpo figurado.Procederemos a semejanza del test de Rorschach que consiste en “encontrar” una figura en una simple mancha de tinta sobre el papel —en nuestro caso, sin ningún fin psicológico sino puramente imaginativo, en el sentido de crear imágenes—, a la vez que iremos poniendo en evidencia el estrecho vínculo que hay, en la poesía de Gervitz, entre la escritura del cuerpo y el cuerpo de la escritura.