bluuebunny/crossref_metadata_2025 huggingface dataset:
Prevalence of psychological morbidity and its correlates among school-going adolescents of urban Puducherry, India
Authors: SRINIVASAN MANIKANDAN , PREMARAJAN K.C. , REDDY MAHENDRA M. , MENON VIKAS , KUMAR S. GANESH
Published: November 2022

Background

Experiencing poor mental health during adolescence predisposes an individual to psychiatric morbid conditions in adulthood. We estimated the prevalence of psychological morbidity and its associated factors, among school-going adolescents in higher secondary schools of urban Puducherry.

Methods

We did this cross-sectional study among adolescents studying in classes 11 and 12 from selected schools of urban Puducherry, including one government and three private schools. Study tools used were the General Health Questionnaire-12 and Perceived Stress Scale-10 to assess psychological morbidity and perceived psychological stress in adolescents, respectively. Risk factors in academic, environmental, personal and health-related domains were captured using a structured questionnaire. Study questionnaires were self-administered by the participants in classrooms. Bivariate and multivariate analyses were done to identify risk factors for psychological morbidity.

Results

Of the 820 adolescents surveyed, the prevalence of psychological morbidity was 25.4% (95% CI 22.4– 28.5). Academic factors such as reporting peer pressure for academic performance and lack of extracurricular activities at school were associated with psychological morbidity. Among health-related factors, adolescents who reported having difficulty in coping with pubertal changes, being worried about their physical appearance, reporting substance abuse and experiencing sleep disturbances had greater chances of having screened with psychological morbidity. Of note, adolescents with psychological stress had 2.5 times higher chances of having psychological morbidity.

Conclusions

We estimated that 1 in 4 school-going adolescents in urban Puducherry suffered psychological morbidity. Reducing the academic burden and advocating health promotion through a life skills approach may improve mental wellness in Indian adolescents.
دور مجتمعات التعلم المهنية في تعزيز المهارات الحياتية لدى المعلمين في فلسطين
Authors: الديك سامية عمر , حزبون غريس نصري , عابد غدير ثابت , ناصر إيناس
Published: November 2022

هدفت الدراسة للتعرّف على دور مجتمعات التعلم المهنية في تعزيز المهارات الحياتية لدى المعلمين في محافظات فلسطين، وتكون مجتمع الدراسة من جميع معلمي المدارس الحكومية في محافظات نابلس وجنوب الخليل ورام الله والبالغ عددهم (8831) معلم/ة للعام الدراسي 2021-2022، معلم/ة، واستخدمت الباحثات المنهج الوصفي التحليلي، وتمثلت الأداة في استبانة تكونت من (45) عبارة موزعة على أربعة مجالات؛ تم تطبيقها على عينة طبقية عنقودية بلغت (372) معلماً ومعلمة في محافظات فلسطين. وأظهرت نتائج الدراسة أن دور مجتمعات التعلم المهني في تعزيز المهارات الحياتية لمعلمي المدارس الحكومية في فلسطين جاءت بدرجة عالية وبنسبة مئوية (82.1%). وأسفرت النتائج عن عدم وجود فروق ذات دلالة إحصائية عند مستوى الدلالة (0.05 ≥α) بين متوسطات دور مجتمعات التعلم المهني في تعزيز المهارات الحياتية لمعلمي المدارس الحكومية في فلسطين تعزى لمتغير الجنس، والتخصص، والمؤهل العلمي، والمديرية. وفي ضوء ذلك أوصت الدراسة بضرورة استمرار تفعيل دور مجتمعات التعلم المهني في تنمية المهارات الحياتية وخاصة المهارات الاجتماعية لدى المعلمين من خلال الممارسة والتدريب.
العلاقة بين الأليكسثيميا والسلوك العدواني لدى مرتادي مجمع إرادة والصحة النفسية بمدينة جدة
Authors: الهزازي محمد يحيى
Published: November 2022

هدفت الدراسة الحالية إلى بحث العلاقة بين الأليكسثيميا والسلوك العدواني لدى مرتادي مجمع إرادة والصحة النفسية بمدينة جدة، وقد استخدم الباحث المنهج الوصفي الارتباطي حيث تكوّن مجتمع البحث من مرتادي مجمّع إرادة والصحة النفسية بمدينة جدة، وتم اختيار العينة بطريقة عشوائية بلغت(65) مرتاداً، حيث تم توزيع مقياس تورينتو للألكسثيميا(Tas-20)، من إعداد باجي وزملاؤه (Bagby at el., 1994)، وترجمة (العيدان، 2019)، ومقياس السلوك العدواني الذي صممه بص وبيري Buss & Perry 1992، وعرّبه وقنّنهُ علي البيئة السعودية (عبد الله وأبو عباة, 1995(. وأظهرت نتائج الدراسة توسّط درجات مستوى متغيريّ كلاًّ من الألكسيثيميا والسلوك العدواني لدى مرتادي مجمّع إرادة والصحة النفسية بمدينة جدة. كما كشفت الدراسة عن وجود علاقة ارتباطية بين الأليكسثيميا والسلوك العدواني، وأوصت الدراسة بالتوسّع في الأبحاث التي تدرس مستوى الألكسيثيما وعلاقتها وأثرها باضطرابات الشخصية المتعددة وذلك لندرة بحثه وإعداد البرامج الإرشادية لخفض مستواها لدى المسترشدين.
دور وحدة جودة التعليم والمساءلة في تطوير الكفايات الإدارية لمديري مدارس لواء قصبة إربد من وجهة نظر معلميها
Authors: سايب نعيمة كبيح
Published: November 2022

هدفت الدراسة إلى الكشف عن دور وحدة جودة التعليم والمساءلة في تطوير الكفايات الإدارية لمديري مدارس لواء قصبة إربد من وجهة نظر معلميها، واستخدمت الباحثة المنهج الوصفي التحليلي وتمثلت الأداة في استبانة من (14) عبارة في مجال واحد، تم توزيعها على عينة عشوائية بسيطة بلغت (291) معلماً ومعلمة؛ بالمدارس الحكومية التابعة لمديرية التربية والتعليم في لواء قصبة إربد في الأردن، وبينت نتائج الدراسة أن استجابات أفراد عينة الدراسة حول دور وحدة جودة التعليم والمساءلة في تطوير الكفايات الإدارية لمديري مدارس لواء قصبة إربد من وجهة نظر معلميها جاءت بمتوسط حسابي (3.31)، بدرجة (متوسطة). كما أظهرت النتائج عدم وجود فروق ذات دلالة إحصائية عند مستوى (0.05α≤) تعزى لأثر متغيري (الجنس، وسنوات الخبرة). بينما تبين وجود فروق ذات دلالة إحصائية عند مستوى (0.05α≤) تعزى لأثر متغير المؤهل العلمي ولصالح البكالوريوس. وفي ضوء النتائج أوصت الباحثة بوضع معايير محددة لتطبيق المساءلة التربوية؛ وتبني مديري المدارس فلسفة إدارية وأساليب تنظيمية تدعم مشاركة العاملين في تخطيط وتنفيذ البرامج المدرسية مما يزيد من فاعلية التطوير التنظيمي والكفايات الإدارية للمديرين.
The Effect of Transitioning to Online Learning on the Academic Performance of Upper Basic Stage Female Students in English Language in Amman District Directorate from their Point of View
Authors: Daghmash Heba Hasan , El-Hanbali Saba Azzam
Published: November 2022

The study aimed at identifying the effect of transitioning to online learning on the academic performance of upper basic stage female students in Amman district directorate. The population was (3953) of upper basic stage female students in Amman District directorate. The sample consisted of (375) female students. The questionnaire consisted of (4) dimensions and (32) statements. It was found that the status quo of the academic performance of upper basic stage female students in English language in Amman district directorate before transitioning to online learning was high. The status quo of the academic performance of upper basic stage female students in English language in Amman district directorate after transitioning to online learning was moderate .There were significant differences in the means to identify the status quo of the effect of transitioning to online learning on the academic performance of upper basic stage female students in Amman district directorate, which came in favour of before transitioning to online learning, there were significant differences in the status quo of the academic performance of upper basic stage female students in English language in Amman district directorate after transitioning to online learning, attributed to Grade and English Language Average Score. Several recommendations were presented.
مستوى إتقان طالبات المرحلة المتوسطة لمهارات التواصل الإلكتروني في مقرر الحاسب الآلي وتقنية المعلومات بالمملكة العربية السعودية
Authors: المحمدي نجوى عطيان , الحربي أروى صالح دخيل
Published: November 2022

هدفت الدراسة إلى الوقوف على مستوى إتقان طالبات المرحلة المتوسطة لمهارات التواصل الإلكتروني، في مقرر الحاسب الآلي وتقنية المعلومات بالمملكة العربية السعودية من وجهة نظر معلماتهن، ولتحقيق هدف الدراسة اتبعت الباحثتان المنهج الوصفي المسحي، واستخدمت الاستبانة كأداة للدراسة، مكونة من (12) عبارة، تم تطبيقها على عينة من (102) من معلمات الحاسب الآلي للمرحلة المتوسطة في المدينة المنورةـ وتوصلت الدراسة إلى أن مستوى إتقان طالبات المرحلة المتوسطة لمهارات التواصل الإلكتروني من وجهة نظر معلماتهن كان بمستوى (مرتفع)، وبمتوسط حسابي (4.03) وبنسبة مئوية قدرها (80.6%)، وفي ضوء هذه النتائج أوصت الباحثتان بضرورة تشجيع المعلمات على تعزيز قدرات طالباتهن وتشجعيهن للدخول المتواصل للمنصات التعليمية والمشاركة في الصفوف الافتراضية، وتفعيل حلقات النقاش وتوجيههم للاستخدام الأمثل للتعلم الإلكتروني.
مدى فاعلية نظام الترقية الوظيفية للمعلمين في تحسين دافعية الإنجاز من وجهة نظر معلمي المرحلة الأساسية في قصبة المفرق
Authors: عناجره فواز أحمد
Published: November 2022

هدفت هذه الدراسة للتعرف على مدى فاعلية نظام الترقية الوظيفية للمعلمين (رتب المعلمين) في تحسين دافعية الإنجاز من وجهة نظر المعلمين في تربية قصبة المفرق، ولتحقيق أهداف الدراسة تم اتباع المنهج الوصفي التحليلي من خلال تطوير استبانة وتوزيعها على عينة عشوائية مكونة من (359) معلمًا ومعلمة للمرحلة الأساسية في محافظة المفرق، وتم التحليل الإحصائي باستخدام برنامج (SPSS) تبين أن مستوى فاعلية نظام الترقية الوظيفية للمعلمين (رتب المعلمين) في تربية قصبة المفرق من وجهة نظر المعلمين أنفسهم حصل على متوسط كلي (3.25 من 5) بتقدير فاعلية (متوسطة)، وعلى مستوى المجالات؛ حصل الالتزام بمعايير الترقية على متوسط (3.43) بتقدير فاعلية (كبيرة)، ثم تحقيق أهداف الترقية بمتوسط (3.17)، وأخيرًا تطبيق أسس مبادئ الترقية بمتوسط (3.15) وكلاهما بتقدير (متوسط)، وحصل مجال دافعية الإنجاز لدى معلمي المرحلة الأساسية على متوسط كلي (3.58 من5) بدرجة تقييم (كبيرة). كما بينت النتائج أن العلاقة بين فاعلية نظام الترقية الوظيفية ودافعية الإنجاز بلغت (0.56) وتعكس معامل ارتباط (متوسط)، وهي طردية ودالة إحصائية عند مستوى (α≥0.05). واستنادا للنتائج أوصى الباحث بالاعتماد على تقييم المشرفين للمعلمين، وتطبيق نظام رواتب وحوافز مناسب لطبيعة عمل المعلمين، وتطوير أداء المعلمين؛ بتنويع أنشطة وفعاليات البرامج التدريبية إضافة إلى مقترحات بدراسات مستقبلية.
واقع الصمت التنظيمي لدى قادة المدارس الابتدائية الحكومية للبنين بمدينة بريدة من وجهة نظر المشرفين التربويين والمعلمين
Authors: الشلاش عبدالرحمن سليمان
Published: November 2022

هدفت الدراسة الحالية إلى التعرف على واقع الصمت التنظيمي لدى قادة المدارس الابتدائية بمدينة بريدة من وجهة نظر المشرفين التربويين والمعلمين؛ باستخدام المنهج الوصفي التحليلي، وقد استخدم الباحث استبانة من إعداده كأداة للدراسة، تم تطبيقها على جميع المشرفين التربويين بمدينة بريدة، وعددهم (213) مشرفا ومعلما ابتدائيا، وقد توصلت نتائج الدراسة إلى حصول الأداة على متوسط كلي (1.95 من 3) بتقدير ممارسة (متوسطة) وعلى مستوى الأبعاد حصل تخوف قائد المدرسة من التغذية الراجعة من قبل إدارة التعليم على أعلى متوسط (2.17) يليه التخوف من التغذية الراجعة من المعلمين بمتوسط (1.99) وثالثا ممارسة ما يتعلق بإساءة السطلة الرسمية بمتوسط (1.82) ورابعا ممارسة وسائل الاتصال بمتوسط (1.80) وجميعها بتقدير ممارسة (متوسطة)، كما كشفت الدراسة أن أهم أسباب الصمت التنظيمي قلة دعم الإدارة لمقترحات المعلمين، وتخوف قائد المدرسة من ردود أفعال إدارة التعليم، وقلة صلاحيات قائد المدرسة، وكثرة مسئوليات ومهام القائد، وضعف الخبرة، كما وُجدت فروق ذات دلالة إحصائية بين متوسطات استجابات العينة تبعاً لمتغير الوظيفة لصالح المشرفين التربويين، وتبعا لمتغير المؤهل العلمي لصالح حملة الدكتوراه، واستنادا للنتائج قدم الباحث عددا من التوصيات والمقترحات. من بينها: يجب أن يعمل قائد المدرسة على توفير فرص مشاركة كافية للمعلمين لطرح أفكارهم، على قائد المدرسة عدم الاحتفاظ بكل الصلاحيات لنفسه دون تفويض أحد من فريق العمل.
Soft Potato: an open source electrochemical simulator and toolkit
Authors: Rodríguez Oliver
Published: November 2022

Here, I introduce Soft Potato, an open source electrochemical simulator and toolkit that contains typical electrochemical equations and simulations to aid researchers streamline their data analysis when dealing with large datasets. As examples, I show here how to use it to calculate steady state voltammograms from ultramicrodisc electrodes and obtain a calibration curve from the limiting current as a function of the redox species concentration. This example, showcases the use of the library, as well as the flexibility given by interfacing with third-party libraries to perform data analysis. The second example consists on simulating macroelectrode voltammograms with varying electron transfer rate constants to automate the simulations by iterating over any parameter. Overall, I believe this open source library can be of great help to the electrochemistry community to easily streamline data analysis and potentially obtain immediate feedback for following experiments.
Unique Spin Crossover Pathways Differentiated by Scan Rate in a New Dinuclear Fe(II) Triple Helicate: Mechanistic Deductions Enabled by Synchrotron Radiation Studies
Authors: Wallis Matthew J. , Craze Alexander R. , Zenno Hikaru , Tokunaga Ryuya , Taira Takahiro , Min Hyunsung , Bhadbhade Mohan M. , Bhattacharyya Saroj Kumar , Tian Ruoming , Rich Anne M. , Hayami Shinya , Clegg Jack K. , Marjo Christopher E. , Lindoy Leonard F. , Li Feng
Published: November 2022

The achievement of targeted properties in spin crossover (SCO) materials is complicated by often unpredictable cooperative interactions in the solid state. Herein, we report a dinuclear Fe(II) triple helicate 1, which is a rare example of a SCO material possessing two distinct magnetic behaviors that depend upon the thermal scan rate. Desolvated 1 was seen to undergo spin transition (ST) which was complete following slow cooling (1 K min-1), but incomplete ST (corresponding to 50% conversion) on fast cooling (10 K min-1). The incomplete ST observed in the latter case was accompanied by a higher temperature onset of ST, differing from TIESST (Temperature-Induced Excited Spin-State Trapping) materials. The two SCO pathways have been shown to arise from the interconversion between two structural phases (a and b), with both phases having associated high spin (HS) and low spin (LS) states. SCXRD (Single Crystal X-ray Diffraction) experiments using controlled cooling rates and a synchrotron light source enabled short collection times (2-3 minutes per dataset) which has enabled the identification of a mechanism by which the slow-cooled material may fully relax. In contrast, fast-cooled materials exhibit disordered arrangements of multiple structural phases, which has in turn revealed that the [HS-LS] ↔ [LS-HS] equilibria are controllable in the solid by varying the scan rate. Such behavior has been previously observed in solution studies, but its control in solids has not been reported up to now. This study demonstrates how intermolecular cooperativity can allow multiple distinct magnetic behaviors, and provides some insight into how [HS-LS] ↔ [LS-HS] equilibria can be controlled in the solid state, which may assist in the design of next-generation logic and signaling devices.
Screening Unknown Novel Psychoactive Substances Using GC-MS Based Machine Learning
Authors: Wong Swee Liang , Tan Justin , Ng Li Teng , Pan Jonathan
Published: November 2022

In recent years, there is a large increase in structural diversity of novel psychoactive substances (NPS), exacerbating drug abuse issues as these variants evade classical detection methods such as spectral library matching. Gas chromatography mass spectrometry (GC-MS) is commonly used to identify these NPS. To tackle this issue, machine learning models are developed to address the analytical challenge of identifying unknown NPS, using only GC-MS data. 891 GC-MS spectra are used to train and evaluate multiple supervised machine learning classifiers, namely artificial neural network (ANN), convolutional neural network (CNN) and balanced random forest (BRF). 7 classes, comprising 6 NPS classes (cathinone, cannabinoids, phenethylamine, piperazine, tryptamines and fentanyl) and other unrelated compounds can be effectively classified with a macro-F1 score ~ 0.9, averaged across all cross-validation folds. These results indicate that machine learning models are a promising complement as an effective NPS detection tool.
Minimal Active Space: NOSCF and NOSI in Multistate Density Functional Theory
Authors: Lu Yangyi , Zhao Ruoqi , Zhang Jun , Liu Meiyi , Gao Jiali
Published: November 2022

In this Perspective, we introduce a minimal active space (MAS) for the lowest N eigenstates of a molecular system in the framework of a multistate density functional theory (MSDFT), consisting of no more than N2 nonorthgonal Slater determinants. In comparison with some methods in wave function theory in which one seeks to expand the ever increasing size of an active space to approximate the wave functions, it is possible to have an upper bound in MSDFT because the auxiliary states in a MAS are used to represent the exact N-dimensional matrix density D(r). In analogy to Kohn-Sham DFT, we partition the total Hamiltonian matrix functional H[D] into an orbital-dependent part, including multistate kinetic energy Tms and Coulomb exchange energy EHx plus an external potential energy R dr v(r)D(r), and a correlation matrix density functional Ec[D]. The latter accounts for the part of correlation energy not explicitly included in the minimal active space. However, a major difference from Kohn-Sham DFT is that state interactions are necessary to represent the N-matrix density D(r) in MSDFT, rather than a non-interacting reference state for the scalar ground-state density ρo(r). Two computational approaches are highlighted. We first derive a set of non-orthogonal multistate self-consistent-field (NOSCF) equations for the variational optimization of H[D]. We introduce the multistate correlation potential, as the functional derivative of Ec[D], which includes both correlation effects within the MAS and that from the correlation matrix functional. Alternatively, we describe a non-orthogonal state interaction (NOSI) procedure, in which the determinant functions are optimized separately. Both computational methods are useful for determining the exact eigenstate energies and for constructing variational diabatic states, provided that the universal correlation matrix functional is known. It is hoped that this discussion would stimulate developments of approximate multistate density functionals both for the ground and excited states.
Minimal Active Space: NOSCF and NOSI in Multistate Density Functional Theory
Authors: Lu Yangyi , Zhao Ruoqi , Zhang Jun , Liu Meiyi , Gao Jiali
Published: November 2022

In this Perspective, we introduce a minimal active space (MAS) for the lowest N eigenstates of a molecular system in the framework of a multistate density functional theory (MSDFT), consisting of no more than N2 nonorthgonal Slater determinants. In comparison with some methods in wave function theory in which one seeks to expand the ever increasing size of an active space to approximate the wave functions, it is possible to have an upper bound in MSDFT because the auxiliary states in a MAS are used to represent the exact N-dimensional matrix density D(r). In analogy to Kohn-Sham DFT, we partition the total Hamiltonian matrix functional H[D] into an orbital-dependent part, including multistate kinetic energy and Coulomb-exchange energy plus an external potential energy, and a correlation matrix density functional Ec[D]. The latter accounts for the part of correlation energy not explicitly included in the minimal active space. However, a major difference from Kohn-Sham DFT is that state interactions are necessary to represent the N-matrix density D(r) in MSDFT, rather than a non-interacting reference state for the scalar ground-state density. Two computational approaches are highlighted. We first derive a set of non-orthogonal multistate self-consistent-field (NOSCF) equations for the variational optimization of H[D]. We introduce the multistate correlation potential, as the functional derivative of Ec[D], which includes both correlation effects within the MAS and that from the correlation matrix functional. Alternatively, we describe a non-orthogonal state interaction (NOSI) procedure, in which the determinant functions are optimized separately. Both computational methods are useful for determining the exact eigenstate energies and for constructing variational diabatic states, provided that the universal correlation matrix functional is known. It is hoped that this discussion would stimulate developments of approximate multistate density functionals both for the ground and excited states.
Utilizing Biocatalysis and an Unprecedented Sulfolane-mediated Reductive Acetal Opening to Access Nemtabrutinib from Cyrene
Authors: Kuhl Nadine , Turnbull Ben W. H. , Ji Yining , Larson Reed T. , Shevlin Michael , Prier Christopher K. , Chung Cheol K. , Desmond Richard , Guetschow Erik , He Cyndi Qixin , Itoh Tetsuji , Kuethe Jeffrey T. , Newman Justin A. , Reibarkh Mikhail , Rivera Nelo R. , Shang Gao , Wang Zhixun , Zewge Daniel , Thaisrivongs David A.
Published: November 2022

The chiral building block 5-amino-2-hydroxymethyltetrahydropyran 1a has been previously synthesized through a cumbersome 9-step synthesis from tri-O-acetyl-D-glucal, which renders access to nemtabrutinib (2), a BTK inhibitor currently being evaluated for the treatment of various hematologic malignancies, inefficient and wasteful. Herein, we describe the development of a protecting group-free, 2-step synthesis of 1a from Cyrene, a biorenewable feedstock. The improved synthesis involves a biocatalytic transamination reaction of Cyrene to install the desired amine-stereocenter in a single step with high diastereoselectivity. The enzymatic reaction is followed by a stereo-retentive reductive acetal opening reaction of the chiral cyrene amine intermediate 3a to furnish 1a. A mechanistic investigation of the acetal opening reaction is also described which uncovered unprecedented reaction conditions for the in-situ generation of diborane mediated by the sulfolane co-solvent. The streamlined synthesis of 1a from Cyrene resulted in a > 27% yield improvement and a significant reduction in the environmental impact of the synthesis.
Microfluidic quantum sensing platform for lab-on-a-chip applications
Authors: Allert Robin Derek , Bruckmaier Fleming , Neuling Nick Ruben , Freire-Moschovitis Fabian Alexander , Liu Kristina Song , Schrepel Claudia , Schätzle Philip , Knittel Peter , Hermans Martin , Bucher Dominik Benjamin
Published: November 2022

Lab-on-a-chip (LOC) applications have emerged as invaluable physical and life sciences tools. The advantages stem from advanced system miniaturization, thus, requiring far less sample volume while allowing for complex functionality, increased reproducibility, and high throughput. However, LOC applications necessitate extensive sensor miniaturization to leverage these inherent advantages fully. Atom-sized quantum sensors are highly promising to bridge this gap and have enabled measurements of temperature, electric and magnetic fields on the nano- to microscale. Nevertheless, the technical complexity of both disciplines has so far impeded an uncompromising combination of LOC systems and quantum sensors. Here, we present a fully integrated microfluidic platform for solid-state spin quantum sensors, such as the nitrogen-vacancy (NV) center in diamond. Our platform fulfills all technical requirements, such as fast spin manipulation, enabling full quantum sensing capabilities, biocompatibility, and easy adaptability to arbitrary channel and chip geometries. To illustrate the vast potential of quantum sensors in LOC systems, we demonstrate various NV center-based sensing modalities for chemical analysis in our microfluidic platform, ranging from paramagnetic ion detection to high-resolution microscale NV-NMR. Consequently, our work opens the door for novel chemical analysis capabilities within LOC devices with applications in electrochemistry, high throughput reaction screening, bioanalytics, organ-on-a-chip, or single-cell studies.
Low-temperature electrochemical ammonia synthesis: recent progress and comparison to Haber-Bosch in terms of energy efficiency
Authors: Rezai Fateme , Ege Sahin Nihat , Læsaa Søren , Catalano Jacopo , Dražević Emil
Published: November 2022

The electrochemical synthesis of ammonia, in the literature often referred to as Electrochemical Nitrogen Reduction Reaction (ENRR), has gained attention as a milder alternative to the Haber-Bosch process, which requires high temperature and pressure. Recently, several breakthrough scientific papers were published showing a way to achieve nearly 100% selectivity of the ENRR over hydrogen reduction at very high production rates, which had been identified earlier as a main challenge. These results motivated the present study to benchmark the energy efficiencies of the most reliable ENRR studies against the Haber-Bosch process. ENRR studies historically suffered from reliability issues due to low ammonia production rates, which were often within the range of ambient ammonia contamination, potentially leading to false positive measurements. Consequently, rigorous experimental protocols have been published in the last four years. Here we first reviewed the protocols and established a methodology and a reliability indicator to assess the reliability of the results. Then we used the indicator to evaluate the studies reported in the literature from January 2019 to Aug 2022. Finally, we discussed and calculated the energy efficiency of ENRR for works that were assessed as reliable and probably reliable with the indicator. We identified and discussed several promising systems and strategies enabling higher energy efficiency. The energy efficiency had a maximum of 41%, which is within the efficiency range of current Haber-Bosch plants. However, ENRR energy efficiencies must improve to get closer to the 56% some of the state-of-the art Haber-Bosch plants achieve.
Critical review on uranium and arsenic content and their chemical mobilization in the groundwater: A case study of the Malwa region Punjab, India
Authors: kumar vajinder , Saha Sandip , Kumar Avneesh , Maity Arnab , Mukherjee Tirtha , Kumar Atul
Published: November 2022

Groundwater played a pivotal role in the social and economic development of the Malwa Region. With the advent of the green revolution, water for irrigation and domestic use led to the development of groundwater resources. Slowly, the green revolution changed into a greed revolution, and the exploitation of groundwater resources converted into their overexploitation. Groundwater's overexploitation not only led to groundwater depletion but also led to a change in the chemistry of the Malwa region's aquifers. Researchers from academia and institutions worked and published their findings of the uranium and arsenic contaminations in the Malwa region of Punjab. In this article, we are the first to bring all the dispersed data to one commonplace. By studying the physicochemical parameters of groundwater of all districts of the Malwa region and their correlation, this paper is going to highlight the various chemical reactions occurring in the Malwa region's aquifer and how they impact groundwater chemistry. For understanding, we devised a hypothetical model to understand the complex interplay of this region's natural dynamics of groundwater aquifers. Finally, we tried to describe how the various chemical changes in the groundwater aquifer can be the reason for the mobilization of arsenic and uranium by making schematic chemical flow-charts of their mobilization. This article aims to highlight the importance of using a multidisciplinary and interdepartmental approach to comprehending the complex problem of groundwater management.
13C and 15N NMR Detection of Metabolites via Relayed Hyperpolarization at 1 T and 1.4 T
Authors: Alcicek Seyma , Dyke Erik Van , Xu Jingyan , Pustelny Szymon , Barskiy Danila
Published: November 2022

Nuclear-spin hyperpolarization allows various magnetic-resonance applications in chemistry and medicine that are unattainable by standard methods. For such applications, parahydrogen-based hyperpolarization approaches are particularly attractive because of their technical simplicity, low cost, and ability to quickly (in seconds) produce large volumes of hyperpolarized material. Although many parahydrogen-based techniques have emerged, some of them remain unexplored due to the lack of careful optimization studies. In this work, we investigate and optimize a novel parahydrogen-induced polarization (PHIP) technique that relies on proton exchange referred to below as PHIP-relay. An INEPT (insensitive nuclei enhanced by polarization transfer) sequence is employed to transfer polarization from hyperpolarized protons to heteronuclei (15N and 13C) and nuclear signals are detected using benchtop NMR spectrometers (1 T and 1.4 T, respectively). We demonstrate the applicability of the PHIP-relay technique for hyperpolarization of a wide range of biochemicals by examining such key metabolites as urea, ammonium, glucose, amino acid glycine, and a drug precursor benzamide. By optimizing chemical and NMR parameters of the PHIP-relay, we achieve a 17,100-fold enhancement of 15N signal of [13C, 15N2]-urea compared to the thermal signal measured at 1 T. We also show that repeated measurements with shorter exposure to parahydrogen provide a higher effective signal-to-noise ratio compared to longer parahydrogen bubbling.
Total alopecia and vascular malformation: a random association or a prognostic factor?
Authors: Golousenko Igor Yu. , Solovyov Anton M. , Solovev Fedor A.
Published: November 2022

Background. Alopecia areata (AA) is a chronic recurrent autoimmune disease that leads to a deterioration in the quality of life. And capillary malformation (CM) occurs in 1/3 of AA patients.
Aim. To identify the connection of one of the forms of AA with CM in the occipital region.
Materials and methods. 18 patients with total alopecia (TA), 5 men and 13 women were under observation. The age ranged from 26 to 58 years, the duration of the disease ranged from 1 to 29 years. To determine the relationship between CM and TA, the odds ratio was used with the corresponding 95% confidence intervals.
Results. The study showed the occurrence of CM in patients with TA in 94.4%. The correlation of CM and TA turned out to be statistically significant in comparison with the control group.
Conclusion. The results indicate that there is a reliable relationship between CM and TA, which allows us to conclude that CM is associated with severe forms of alopecia. In addition, CM can be a valuable marker and prognostic factor indicating the development of more severe forms and course of AA.
Itchy scalp
Authors: Katkova Ksenia V. , Plieva Kristina T. , Denisova Elena V. , Zhukova Olga V. , Korsunskaya Irina M.
Published: November 2022

Itchy scalp troubles many people. The causes of itching can be systemic, psychogenic, neurological, and dermatological diseases. The most common dermatological diseases associated with scalp itching are seborrheic dermatitis and psoriasis. The pathogenesis of these diseases is very different, but in both cases, skin microbiota changes may present, supporting the inflammation. Also, in both conditions, flaking and other similar clinical presentations occur. In addition to adequate therapy, the choice of care product is important. For a patient with scalp disease, the specialist should recommend shampoo and other products that can complement the basic therapy. Such products should have some features: they should help to normalize the microbiota and pH, relieve inflammation, and eliminate unpleasant symptoms, including itching. One such product is LE SANTI shampoo, which shows good clinical efficacy for several dermatological diseases.
Dermatologic masks of Langerhans cell histiocytosis. Case report
Authors: Belysheva Tatiana S. , Valiev Timur T. , Murashkin Nikolay N.
Published: November 2022

Langerhans cell histiocytosis (LCH) is a rare pathology in pediatric age with heterogeneous clinical presentation in skeletal system, skin, central nervous system, liver, spleen, lungs, lymph nodes and bone marrow. Therefore, a number of diagnostic mistakes increase and inadequate therapy administrates. For a diagnostic period, a try at treatment, LCH disseminates with organs and systems involvement and at the moment of morpho-immunologic diagnosis verification, a disease characterizes as multiorgan multiple site affection, which decreased survival rate. In the current issue a clinical case of LCH with mistaken prolonged (2 year) atopic dermatitis anamneses is presented. The absence of pronounced effect of topical therapy along with nontypical for atopic dermatitis became not an indication for skin biopsy. After appearance of systemic symptoms with anemia, leuko- and thrombocytopenia became an evidence for pediatric oncologist-hematologist consultation.
Syndrom Parry–Romberg: clinical case of a rare disease
Authors: Perlamutrov Yuri N. , Volkova Svetlana B. , Olhovskaya Kira B. , Godzenko Tatiana A.
Published: November 2022

The article is devoted to ParryRomberg syndrome, one of the rare diseases. Here we declare contemporary views on predisposing factors, pathogenesis and character of clinical performance. We describe the methods of differential diagnostics, the criteria of diagnostics as well as contemporary treatment methods. We also describe a case history of the disease.
Fungal sensitization in patients with severe atopic dermatitis as a distinct phenotype
Authors: Fomina Daria S. , Lebedkina Marina S. , Chernov Anton A. , Nikitina Ekaterina A. , Mukhina Olga A. , Mikhaylova Valeriya I.
Published: November 2022

Background. Many factors influence the development of atopic dermatitis (AD): genetic, environmental (including exposure to allergens), skin barrier damage, and activation of the T2-pathway immune response. Patients with AD, including those with severe disease, are prone to sensitization to various allergens, including fungal ones. Fungal sensitization (FS) promotes autoreactivity to the body's own structures due to shared epitopes with homologous fungal allergens. It can contribute to the development of allergic diseases, including AD, asthma, and rhinitis, as well as to their exacerbation and uncontrolled course. Since FS can be considered a factor aggravating AD, it is relevant to distinguish patients with FS and AD into a separate phenotype.
Aim. To characterize the phenotype of patients with severe AD and FS using retrospective data analysis from a digital analytics platform in a real-world clinical setting.
Materials and methods. A retrospective observational single-center study was conducted between 01.06.2017 and 01.07.2022. The study cohort included 88 patients with severe AD who were candidates for therapy or received treatment with either dupilumab or upadacitinib. FS was confirmed in 49 patients from the study group. Part of the cohort without FS (n=39) was used as a comparison group. Inclusion criteria: the age over 18 years old; severe AD (SCORAD40 points at the beginning of therapy); determination of specific immunoglobulin E to a panel of fungal allergens or individual fungi (or by the ImmunoCAP ISAC method to fungal allergen components). A digital analytics platform was used to generate primary data.
Results. The phenotype of a patient with severe AD and confirmed FS was described. The patient profile is characterized by an extended sensitization spectrum (at least 34 allergen groups) with the most typical combination of pollen, epidermal, and FS. If there is a food allergy, it is of the classic "big eight" nature. Besides exacerbation of the skin disorder, its manifestations include angioedema of life-threatening localization and bronchospasm. Markers of T2 inflammation (high levels of immunoglobulin E and blood eosinophilia) are observed according to the test results, and the T2 endotype of allergy-related abnormalities is typical.
Conclusion. Apparently, the presence of FS in patients with AD may exacerbate parenteral sensitization mechanisms, expanding its spectrum, including food allergens. Therefore, distinguishing the phenotype of severe AD with FS needs further detailing with a subsequent adaptation of monitoring and treatment methods of severe AD.
Investigation of the Physical Properties and Droplet Combustion Analysis of Biofuel from Mixed Vegetable Oil and Clove Oil
Authors: Gamayel Adhes , Zaenudin Mohamad , Mohammed M. N. , Yusuf Eddy
Published: November 2022

The study of vegetable oil used as fuel in conventional engines leads to problems like the low volatility and high viscosity. This research aims to evaluate the droplet combustion characteristics that correlated with the density, viscosity, and the flash point of the biofuel from mixed vegetable oil with clove oil. Biofuels used in research are Jatropha Oil (CJO), Kapok Oil (KSO), Coconut oil (CCO), and all biofuel mixed with clove oil in 5% basis volume. Fuel properties that tested both biofuel and fuel mixture using the ASTM method are density (ASTM D1298), viscosity (ASTM D445), The flash point (ASTM D93). The droplet combustion experiment used suspended droplets placed in the junction of the K-type thermocouple and the Ni-Cr wire (as the coil heater) to heat the droplet until the combustion occurred. The result indicates that adding 5% clove oil in biofuel creates higher density, the viscosity decreases until 10%, and the flash point decrease to 30%. Droplet combustion results that adding 5% clove oil creating a more complete combustion process in CCO than KSO and CJO. Higher viscosity in KSO and CJO leads to eugenol and terpene (clove oil compound) trapping in the fuel droplet. Due to eugenol and terpene having great volatility, they are evaporating rapidly leading to secondary atomization and micro-explosion phenomena.
SAFETY OF PARTICIPANTS IN CRIMINAL PROCEEDINGS
Authors: Koretsky Oleg Pavlovich , Koretska Victoria Vitalievna
Published: November 2022

Introduction. Security must be ensured in various spheres of socially significant activity. As criminal proceedings are one of the most important activities of the state, the issue of ensuring the safety of participants in criminal proceedings becomes particularly relevant. The term "security of participants in criminal proceedings" is not an abstract concept, as security must be provided to specific persons involved in criminal proceedings, and if there are real grounds for doing so.

Summary of the main research results. The need to ensure the safety of participants in criminal proceedings in Ukraine arose not so long ago as some other criminal procedural institutions (for example, the Institute for the Protection of Suspects and Accused). Many procedural scholars have dealt with this issue. It is proposed to expand the provisions on ensuring the safety of a person harmed by a crime and to specify that such security should be provided to a natural person who has suffered from a crime, regardless of his status as a victim, and to a representative of a legal entity in case of property damage. reputation of this legal entity.

Conclusions. It should be noted that the vast majority of proposals developed and substantiated by criminal procedure science were requested by the legislator to form a system of security measures enshrined in the CPC of Ukraine. At the same time, a large number of issues related to the establishment of criminal security measures remain unresolved to this day. Ways to improve the current legislation of Ukraine are suggested.
ІННОВАЦІЇ В ГОТЕЛЬНО-РЕСТОРАННІЙ ІНДУСТРІЇ
Authors: Паска Марія Зіновіївна , Радзімовська Ольга Володимирівна , Гузенко Ірина Іллівна , Гузенко Анастасія Юріївна , Холявка Володимир Зеновійович
Published: November 2022

Успіх у веденні бізнесу залежить від вчасного реагування на потреби ринку в модернізації та задоволенні назрілих потреб споживачів, у підтримуванні екологічних трендів у харчуванні. Метою роботи є визначення міжнародних інноваційних трендів у готельно-ресторанній індустрії, а також аналіз, дослідження та визначення затребуваності екопродукції у споживчому секторі України. У готельно-ресторанному бізнесі є низка вагомих розробок, серед яких праці Архіпова В. В., Калашникова О. Ю., Карпенка В. Д., Мостової Н. О., Нечаюк Л. І., Новикової О. В., П’ятницької Г. Т., Сірого В. М. та ін. Завдання, які потребують вирішення: 1. Аналіз технічних сервісів та особливостей міжнародних трендів інноваційного розвитку у готельно-ресторанній індустрії. 2. Аналіз переваг виробництва органічних продуктів в Україні, а також дослідження ринку еко-продуктів для постачання у ресторани. Методами дослідження було обрано метааналіз інформаційних джерел, емпіричні спостереження, системний підхід. Постановка проблеми: проаналізувати міжнародні інноваційні тренди у сфері готельно-ресторанної індустрії. Результат дослідження. Сучасний ресторан, клуб чи кав'ярня сприяє комфортному проведенню часу. У готельно-ресторанній індустрії завжди в тренді оригінальне подання та оформлення страв. У елітних ресторанах частують молекулярною кухнею. У дизайні інтер’єру популярним стає скандинавський стиль. Піклування про здоров’я споживачів стало черговим популярним трендом. Ресторани та кав’ярні закуповують екопродукцію з фермерських угідь, де вирощують овочі, фрукти без використання хімічних добавок, доглядають за тваринами. Адресне обслуговування відвідувачів включає люб’язність, ввічливість, комунікабельність, розуміння та персональний підхід з боку обслуговуючого персоналу. Впровадження інновацій та digital-технологій сприяє збільшенню кількості відвідувачів, розширенню асортименту продукції та способів її подачі, а також пошуку нових оригінальних рішень. Інновації в готельно-ресторанній індустрії сприяють гарантованому успіху у готельно-ресторанній індустрії.
Coordinators’ leadership styles and teachers’ perceived level of job performance and job satisfaction in primary private school in Lebanon. (c2022)
Authors:   ,   Lebanese American University, Hably Farah
Published: November 2022

Leadership style is defined as a leader’ characteristic behaviours when working with a group of people. At school, coordinators might have different leadership styles they use with teachers. An effective leadership style would increase employees’ satisfaction and enhance their performance level. The purpose of this study is to investigate how teachers perceive their job performance and satisfaction according to two different leadership styles: transformational and transactional. Quantitative and qualitative data were collected through a questionnaire and an interview. Participants consisted of 31 teachers working at the elementary level in a private school in Beirut. Results were mostly comparable, showing that teachers feel satisfied and perform better when working with a coordinator who has a transformational leadership style. That is, one who recognizes that teachers have different abilities and needs, who spends time coaching and training, who communicates a common vision and mission, who projects confidence that goals can be achieved, who talks optimistically about future goals, and who gets teachers to look at problems and solve them from multiple perspectives. Further research is needed on a larger scale to confirm these results.
Keputusan Investasi Digital dan Transaksi Non Tunai Investor Muslim
Authors: Nurohman Yulfan Arif , Qurniawati Rina Sari
Published: November 2022

Muslim investors invest for financial gain in the future. The current investment decision determines the profit or loss received. The purpose of the study was to determine how much financial literacy and risk tolerance influence in determining digital investment decisions and to find out how much financial literacy and risk tolerance influence in conducting non-cash transactions during the covid-19 pandemic for Muslim investors. The research was conducted on Muslim investors in Sukoharjo Regency. Determination of the sample using purposive sampling with the number of respondents as many as 110. Data collection was done using a questionnaire distributed to Muslim investors who have done investment activities. Testing the model using Path Analysis with SmartPLS Software by performing Individual Item Reliability Test, Internal Consistency Test, and Discriminant Validity Test. The test results show that the financial literacy of Muslim investors has no effect on investment decisions and non-cash transaction decisions. Meanwhile, risk tolerance affects investment decisions and non-cash transaction decisions. The investment decisions of a Muslim are not based on their financial knowledge but on the current economic situation.
Profit Terhadap Return Perusahaan Manufaktur Indonesia dan Malaysia
Authors: Annisa Qurrota’ayun  , Diah Ayu Kususmawati
Published: November 2022

The purpose of this study was to examine and analyze the effect of profitability variables on stock returns of manufacturing companies in Indonesia and Malaysia. Total sample in this study was 302 companies using purposive sampling method. Based on the results of statistical tests, it is shown that in Indonesia the independent variable that affects return is only EPS and size is not a control variable. In Malaysia, the variables that can have a significant effect on returns are only EVA and ROA, the size of the Malaysian sample cannot be used as a control variable. In the combined sample of Indonesia and Malaysia, the variable size can be used as a control and the variables that can have a significant positive effect are EPS, ROE and ROA.
Analisis Komparatif Kinerja Reksadana Syariah Di Indonesia Sebelum Dan Saat Pandemi Covid-19
Authors: Hapsari Tri Dyah
Published: November 2022

This research aims to find out how to optimize the function of the mosque as a means of da'wah and economic empowerment of the people. The subject of this research is the Assalam Mosque located in Rowosari Village, Ulujami District, Pemalang Regency. This research uses a descriptive qualitative method. Data analysis by triangulation, data obtained through observation and interviews with informants of the management and congregation of the Assalam Mosque. The results show that, apart from functioning as a place of worship, Masjid Assalam seeks to optimize its other functions as a center for da'wah for youth, youth and adult congregations. Other parts carried out at the Assalam Mosque are social functions in distributing rice alms to pilgrims, collecting and distributing aid to disaster victims, and economic empowerment to stalls and shops owned by pilgrims.
STEAM Dijital Oyun Platformunda Bulunan Eğitici İçerikli Dijital Oyunların Elektrik-Elektronik Mühendisliği Öğretim Müfredatına Entegrasyonu İçin Öneriler
Authors: Fidan Şehmus , Karaman Ömer Ali , Yıldırmaz Abdullah
Published: November 2022

Bu makalede eğitici içeriğe sahip dijital video oyunları ele alınmış olup Elektrik-Elektronik Mühendisliğine entegrasyonu için STEM (Bilim, Teknoloji, Mühendislik, Matematik) felsefesi içinde bazı değerlendirilmeler yapılmıştır. STEM kavramına daha sonradan sanat kavramı da eklenerek genişletilen STEAM (Bilim, Teknoloji, Mühendislik, Sanat, Matematik) felsefesiyle aynı ismi taşıyan STEAM dijital oyun dağıtım platform 30.000’i geçen sayıda oyun sunmaktadır. Bu platform ayrıca en fazla eğitici içerikli dijital video oyunu sunan platform olarak dikkat çekmektedir. Eğitici içeriğe sahip dijital oyunlar öğrencilerin derse daha fazla katılımını sağlayarak motivasyonun arttırılmasına, alan yeterliliğine ve takım çalışmasına olumlu katkı sunmaktadır. Eğitici içerikli oyunların belirlenmesi için STEAM oyun platformu içinde 100’den fazla oyun değerlendirmeye alınmış ve eğitici içeriğe sahip olanlar belirlenmiştir. Örnek olarak seçilen bazı oyunlar için incelemeler sunulduktan sonra en fazla indirilme ve olumlu yorum alma durumlarına göre değerlendirilmiştir. Literatürde seçilen eğitici içerikli oyunlar için bir sınıflandırma yapılmadığı için öneride bulunulmuştur. Yapılan incelemeler sonunda belirtilen oyunların Elektrik-Elektronik Mühendisliği bölümü müfredatına eklenebileceği ancak dikkate alınması gereken eksiklikler bulunduğu belirtilmiş ve öneriler sunulmuştur.