bluuebunny/crossref_metadata_2025 huggingface dataset:
Influence of inorganic nanofiller on the properties of poly(ethylene oxide)/poly(methyl acrylate) composite polymer electrolytes
Authors: Abdul Halim Suhaila Idayu , Zainal Nurul Fatahah Asyqin , Chan Chin Han , Kressler Jӧrg
Published: May 2023

The effect of titanium dioxide (TiO2) on the thermal properties, morphology, intermolecular interactions, and dielectric response of poly(ethylene oxide)/poly(methyl acrylate) (PEO/PMA) polymer electrolytes was studied. These properties were elucidated based on the empirical point of view through systematic sample characterization using differential scanning calorimetry (DSC), polarized optical microscopy (POM), Fourier-transform infrared (FTIR) spectroscopy and impedance spectroscopy (IS). Without TiO2, lithium perchlorate preferably dissolves in the PEO phase rather than in the PMA phase. When TiO2 is added into PEO/PMA/salt systems, TiO2 shows weak interactions either with PEO or PMA phase. The addition of TiO2 changes the morphology of PEO/PMA systems with or without salt from a homogeneous mixture to a heterogeneous mixture displayed by the presence of two T
gs and through the morphological study. The conductivity of both PEO/PMA with and without salt systems remains constant upon the addition of TiO2. Hence, the presented data here have shown that TiO2 provides only a minor effect on the properties of PEO/PMA with and without salt systems. Indirectly, it shows by adding TiO2 under this experimental study may not bring a significant contribution to the improvement of polymer electrolytes.
Ultra-low latency communication technology for Augmented Reality application in mobile periphery computing
Authors: Nagu Bharathiraja , Arjunan Thiruneelakandan , Bangare Manoj L. , Karuppaiah Pradeepa , Kaur Gaganpreet , Bhatt Mohammed Wasim
Published: May 2023

Improved Reliability and Low Latency Communication (IRLC) with Augmented Reality (AR) has become an emerging technology in today’s world. To minimize an accessory adaptation for Customer Equipment (CE) in AR, it may be feasible to offload the AR workload onto the onboard devices. Mobile-Edge Computation (MEC) will improve the throughput of a CE. MEC has caused enormous overhead or communication omissions on wireless media, making it difficult to choose the optimal payload proposition. The proposed system explores on-board devices that work together to achieve an AR goal. Code splitting is a Bayesian network used to examine the overall interdependence of efforts. From a longevity and endurance perspective, it is used to reduce the Probability of Supplier Failure (PSF) of an MEC-enabled AR environment. Weighed Particle Swarm Optimization (WPSO) was proposed despite the reality based on the emphasis on balancing the issue. As a result, a heuristic-based WPSO facilitates to improve the performance measures. A hybrid method could significantly increase the assertion of a predicted PSF in various network scenarios compared to the existing communication technologies. A preliminary iterative approach is suitable for AR operations and IRLC scenarios to generalize the attributes.
Hydration Reaction of Cementitious Composites with Calcium Silicate Slag
Authors: Bai Ru , Zhang Ju , Yan Changwang , Liu Shuguang , Wang Xiaoxiao , Liu Zhigang
Published: May 2023

Calcium silicate slag (CSS) is a secondary solid waste produced during the extraction of aluminum oxide (Al2O3) from fly ash. Pulverized CSS can replace part of portland cement as a supplementary cementitious material. This study investigates the content of chemically bound water and the hydration degree of a CSS-cement system while varying the CSS content, water–binder ratio, and hydration age. Results show that adding CSS can appropriately reduce the content of chemically bound water and the hydration degree. A cube hydration model suitable for the CSS-cement system was established, which considered the spatial distribution and the evolution of cement and CSS particles in the hydration unit. Based on the cubic hydration model, the growth process of hydration products of CSS and cement particles was analyzed, the expression for the volume of CSS and cement particles at different hydration stages was deduced, and the hydration degree of the CSS-cement system was calculated. The calculated value of the hydration degree was compared with the test value to verify the correctness of the former. Overall, the results provide a practical experimental and theoretical framework to understand the application of the CSS-cement system.
Immunohistochemical Expression of Cytokeratin 19 in Patients with Papillary Thyroid Carcinoma and its Mimics in Erbil, Kurdistan Region, Iraq
Authors: Dizeyi Tavga
Published: May 2023

Background and objective: Papillary thyroid carcinoma (PTC) is the most common primary thyroid cancer. PTC diagnosis is based on the presence of classic nuclear features in most cases. However, there are some mimics including both benign neoplastic and non-neoplastic lesions, therefore immune-histochemical stains are necessary for equivocal cases. This study aimed to evaluate the diagnostic expression of CK19 in different thyroid lesions and also to differentiate PTC from other mimicking thyroid lesions. Methods: A retrospective study of 90 cases of different thyroid lesions (56 patients with benign neoplastic and non-neoplastic lesions and 34 PTC) was investigated from January 2018 to January 2020. Immunohistochemical staining with CK19 was performed. Results: CK19 IHC expressed in about 94% of PTC cases as moderate and strong pattern of staining, while in benign neoplastic and non-neoplastic thyroid lesions only 7% expressed as moderate and non with strong pattern of staining, it showed a significant statistical difference (P <0.001).The sensitivity and specificity of CK19 total estimated score for diagnosis of PTC were 94.1% and 92.9%, respectively. Conclusion: Although no single immunohistochemical marker is completely sensitive in differentiating benign from thyroid malignancy, this study found a significant and effective role of CK19 in distinguishing PTC from benign neoplastic and non-neoplastic mimickers’ lesions. In addition, lymph node metastatic tumor cells retained the same staining intensity of CK19.
The impact of rosuvastatin on inflammatory markers in L-NAME induced hypertensive rats
Authors: Dizaye Kawa , Berzinji Begard
Published: May 2023

Background and objective: Many clinical trials have revealed that HMG-CoA reductase inhibitors (statins) have anti-inflammatory effects through their pleiotropic activities there by decreasing the risk of cardiovascular disease (CVD). This study intended to evaluate the effect of rosuvastatin on the level of inflammatory markers (hsCRP, IL-6, sCD40L, Lp-PLA2, and cystatin C) in normotensive and hypertensive rats. Methods: Twenty-four male Wister rats were divided into two groups of twelve. Group 1 consisted of normotensive rats, while Group 2 served as the hypertensive model. Each group was further subdivided into two groups. Subgroup A served as the control group which received the only placebo and subgroup B was the treatment arm which received rosuvastatin 10mg/kg daily for 4 weeks. Results: Rosuvastatin did not significantly affect blood pressure and heart rate in both normotensive and hypertensive rats. The level of inflammatory markers (hsCRP, IL-6, and Lp-PLA2) significantly increased in hypertensive rats, while the level of both sCD40L and cystatin C did not change. Rosuvastatin lowered the level of IL-6, sCD40L, Lp-PLA2, and cystatin C significantly in hypertensive model rats. However, the level of hsCRP was non-significantly reduced by rosuvastatin. In normotensive rats treated with rosuvastatin, the level of cystatin C was significantly reduced. Conclusion: Rosuvastatin significantly decreased the level of IL-6, Lp-PLA2, sCD40L, and cystatin C in hypertensive rats while in normotensive rats, rosuvastatin treatment produced only a reduction of cystatin C. Our results suggest an anti-inflammatory effect of rosuvastatin in hypertention through reduction of inflammatory markers.
Immunohistochemical expression of PTEN (phosphatase and tension homolog) in endometrial carcinoma
Authors: Ali Zena , Berzinji Payman
Published: May 2023

Background and objective: Different molecular alterations have been described in the pathogenesis of endometrial carcinoma, among themis mutation of the PTEN (phosphatase and tension homolog), a tumor suppressor gene. This study aimed to detect PTEN immunoexpression in endometrial carcinoma and to asses the association between PTEN immunoexpression with the clinicopathological parameters. Methods: This cross-sectional retrospective study was carried out between January 2016-December 2021 in Erbil city. A total of 112 formalin fixed, paraffin embedded, archival tissue blocks of total abdominal hysterectomy samples were collected in Erbilcity. The clinicopathological characteristics of the tumors were revised, and the specimens were analyzed immunohistochemically using monoclonal PTEN antibody clone 6H2.1 (Dako. Results: Seventy- seven cases (68.8%) were labeled as negative for PTEN immunoexpression. While 35 cases (31.2%) were labeled as positive for PTEN immunoexpression. PTEN immunoexpression was significantly associated with the tumor histological types (P = 0.001), while no significant association was found between PTEN immunoexpression and other clinicopathological parameters. Conclusion: Loss of PTEN immunoexpression frequently seen in endometrioid type of endometrial carcinoma than other types of endometrial carcinoma and is significantly associated with the histological types of endometrial carcinoma.
Teaching About Climate Change Impacts on Health: Capturing the Experience for Educators
Authors: Lansbury Nina , Mishiro Keiko , Son Kyu-Yeon , Milsom Olivia , Baston Shelby , Buckley Lisa
Published: May 2023

Climate change is a wicked problem. It is valuable for those working in public health to understand the causes, impacts, and possible responses that affect human health. Educators disagree on effective pedagogical strategies that are both engaging and motivating for students. This research evaluated a course involving climate change and health taught to first-year undergraduate students using a survey codesigned and analyzed through a student–staff partnership. The survey found strong correlations between curiosity and interest in learning and motivation to act. The student respondents preferred educational delivery for best learning outcomes included accessible preparatory material, small group tutorials, and guest lecturers providing specialist disciplinary perspectives. The majority considered there is a link between learning about and subsequently acting on climate change, although a need was identified for educators to promote intrinsic motivation within students in addition to disseminating information in classes. In considering the human health impacts of complex health issues, this article provides a valuable capture of course design and teaching methods that can enhance students’ motivation to act beyond the completion of a university course.
Review Kandungan Metabolit Sekunder Tanaman Berkhasiat terhadap Tulang dan Sendi menurut Al-Qanun Fi’l Tibb II
Authors: Siregar Barita Juliano , Sangadji Sarah Nahdah Zhaafirah , Betha Ofa Suzanti , Dhilasari Estu Mahanani
Published: May 2023

Al-Qanun Fi’l Tibb II merupakan buku materia medica karya Ibnu Sina yang terkenal di dunia. Buku tersebut menjelaskan secara rinci mengenai monografi tanaman berkhasiat terhadap organ tubuh, salah satunya terhadap tulang dan sendi. Akan tetapi dalam buku tersebut belum memuat komponen major metabolit sekunder yang diduga berperan penting dalam memberikan efek farmakologis. Penelitian ini ditujukan untuk menginventarisasi tumbuhan yang terdapat di dalam buku Al-Qanun Fi’l Tibb II dan melakukan literatur review terkait kandungan metabolit sekunder yang terdapat dalam tanaman tersebut. Metode penelitian dilakukan dengan literature review melalui studi kepustakaan. Hasil pengambilan data menunjukan terdapat 74 tanaman yang berkhasiat terhadap tulang dan sendi diantaranya memiliki komponen major metabolit sekunder seperti senyawa terpen, flavonoid, alkaloid, tanin, alil isotiosianat, saponin, glikosida, alkohol lemak, asam fenolat, benzofenon, kuinon, sekoiridoid, kumarin, stilbene, anthrone, naftalen, benzaldehida dan asam karboksilat. Terpen merupakan metabolit sekunder yang paling banyak ditemukan dalam tanaman yang berkhasiat terhadap tulang dan sendi. Bioaktivitas yang ditemukan pada tanaman diantaranya antigout, antioksidan, osteoprotektif, antiosteoporosis, antibakteri, antiinflamasi dan analgesik.
On geometric recurrence for time-inhomogeneous autoregression
Authors: Golomoziy Vitaliy
Published: May 2023

The time-inhomogeneous autoregressive model AR(1) is studied, which is the process of the form ${X_{n+1}}={\alpha _{n}}{X_{n}}+{\varepsilon _{n}}$, where ${\alpha _{n}}$ are constants, and ${\varepsilon _{n}}$ are independent random variables. Conditions on ${\alpha _{n}}$ and distributions of ${\varepsilon _{n}}$ are established that guarantee the geometric recurrence of the process. This result is applied to estimate the stability of n-steps transition probabilities for two autoregressive processes ${X^{(1)}}$ and ${X^{(2)}}$ assuming that both ${\alpha _{n}^{(i)}}$, $i\in \{1,2\}$, and distributions of ${\varepsilon _{n}^{(i)}}$, $i\in \{1,2\}$, are close enough.
AUTONOMIA E INOVAÇÃO CURRICULAR
Authors: Julião António Luis
Published: May 2023

O texto focaliza o debate sobre teorias e políticas educativas, argumentando que intentam sobre o controlo dos pensamentos e das práticas que se desenvolvem nas escolas, numa espécie de colonização epistemológica e ontológica dos sujeitos. Propomos, a partir da discussão teórica fundada na revisão bibliográfica interpretativa, ancorada nos pressupostos curriculares críticos e pós-críticos e na nossa prática pedagógica, reflectir sobre a possibilidade de (re)construção do sujeito a partir da criação de espaços para ressignificações e problematizações, possibilitando outras formas de luta para a construção da autonomia, ocasionando uma educação com laivos emancipatórios e transformadores. Defendemos que, a tentativa de fechamento curricular, supondo a possibilidade de controlo, tende a perder força face às demandas contextuais e ontológicas, o que reitera a defesa da necessidade de resistência e questionamento inovadores face aos ditames exógenos por parte dos professores e de um currículo com insígnia da diversidade, cuja significação tenha força para extrapolar margens e ir à procura de uma ilha ainda desconhecida. O texto espera contribuir, estimulando reflexões mais aventuradas, reafirmando a hegemonia da escola, como verdadeiro espaço de ressignificações e centro de decisão das regras do jogo curricular..
CURRÍCULO CULTURAL E BIOLOGIA NA AMAZÔNIA
Authors: Melo Amanda Jessica Coelho , Santos Marcio dos
Published: May 2023

No contexto das mudanças referentes a estrutura da última etapa da educação básica no país, assistimos os movimentos de reorganização dos documentos curriculares acontecendo nas diversas regiões para implementação do chamado novo ensino médio. Com o intuito de estabelecer uma educação de saberes homogêneos e mais pensada para o mercado, a reforma do ensino médio afasta das escolas as discussões que envolvem uma sociedade multicultural. Realizando um movimento contrário a esse, temos neste artigo o propósito de aproximar as reflexões acerca da cultura e da Amazônia, aos espaços educacionais e especialmente ao currículo. Mais especificamente, este estudo tem o objetivo de analisar a influência dos conhecimentos amazônicos no Documento Curricular do Estado do Pará (DCEPA-EM), no campo da Biologia, para isto desenvolvemos uma pesquisa documental, de caráter qualitativo. Nossas lentes investigativas são instigadas por autores que discutem o campo do currículo cultural e a educação amazônida, através dos quais traçamos as reflexões teóricas que são costuradas pelas ponderações resultantes de nossas análises. Os resultados apontam que, por estarmos inseridos no estado do Pará, localizado na região Amazônica, o ensino de biologia poderia se aproximar mais do conhecimento acerca deste bioma, sua rica fauna e flora, sobre os rios e a floresta que compõem e cercam nossas identidades amazônidas e que o DCEPA-EM por um lado utiliza expressões que parecem valorizar as culturas amazônicas, mas segue se alinhando às demandas impostas pelo movimento político educacional mercadológico.
Polymeric materials of secondary industry in bridge engineering
Authors: Anshvaev Adil , Ovchinnikov Igor
Published: May 2023

The article discusses the impact of plastic waste on the environment, disposal methods, and the problems of isolation from the total waste amount. The technology of its recycling is described, as well as the properties of the materials obtained, pros and cons relative to analogs from traditional materials (concrete, steel, and wood), the foreign experience of its use in bridge engineering (construction of new bridges, reconstruction of old bridge structures). The article also analyzes the economic component of construction using building materials from plastic waste and its impact on the environment. A comparison is made of materials from primary polymers and secondary industry polymeric materials. It is shown how things are with plastic waste recycling abroad and in Russia, and what systems are being developed to improve and optimize the recycling process.

The purpose of the article is to point out that humanity needs to reconsider its view of the environmental situation in the world, due to environmental pollution with plastic waste, and to show that there is a way to solve this problem and it is recycling plastic waste. This option of recycling plastic waste will allow us to clean our planet from accumulations of plastic waste (which is formed both on land and in the ocean, adversely affecting flora and fauna) and create competitive, reliable building materials and products that will speed up the process of building bridge structures, facilitate and make more economical the operation of bridges in the future.
Current trends in organising the digital public administration architecture as a new development paradigm
Authors: Pudovkina Olga , Brazhnikov Maxim , Khorina Irina
Published: May 2023

Current global trends of digitalization form a new development paradigm, which entails fundamental changes in the processes of strategic modernization of public administration. The study aims to identify trends in the digital transformation of public administration as a condition for increasing social value through the formation of a platform paradigm.
The authors have developed a model of digital technological architectural environment of public administration, which allows to significantly improve the process of digital interaction with society, with business, but most importantly, to improve the process of efficiency of the state system in the quality of public service delivery.
The authors have structured the definition of the digital transformation of public administration, which represents a transition from the traditional to a holistic transformative approach of digital government.
This article describes the key processes that will define the strategic contours of the digital transformation of public administration, associated with the launch of the next innovation and technology cycle.
The authors have shaped the prospects of using the possibilities of digitalization of public administration, including its digital restructuring, to further its assimilation of the principle of management by results, to improve its efficiency.
To solve the research problems, the authors used a set of scientific methods: system analysis, abstraction, analysis and synthesis. The main method of research was content analysis.
The result of the study is a comprehensive forecast of possible stages of modernization of public administration in conditions of deep penetration of digital technologies, which improve the provision of public services. The development of architectural technological environment will ensure the standardization of digital systems aimed at efficient digital public administration, combining ease of use with high functionality.
The conclusions formed on the implementation of the results of the study will contribute to scientific research aimed at implementing structural change programmes in public administration.
Inhibition of Importin-α–Mediated Nuclear Localization of Dendrin Attenuates Podocyte Loss and Glomerulosclerosis
Authors: Empitu Maulana A. , Kikyo Mitsuhiro , Shirata Naritoshi , Yamada Hiroyuki , Makino Shin-ichi , Kadariswantiningsih Ika N. , Aizawa Masashi , Patrakka Jaakko , Nishimori Katsuhiko , Asanuma Katsuhiko
Published: May 2023

Significance Statement

Nuclear translocation of dendrin is observed in injured podocytes, but the mechanism and its consequence are unknown. In nephropathy mouse models, dendrin ablation attenuates proteinuria, podocyte loss, and glomerulosclerosis. The nuclear translocation of dendrin promotes c-Jun N-terminal kinase phosphorylation in podocytes, altering focal adhesion and enhancing cell detachment–induced apoptosis. We identified mediation of dendrin nuclear translocation by nuclear localization signal 1 (NLS1) sequence and adaptor protein importin-α. Inhibition of importin-α prevents nuclear translocation of dendrin, decreases podocyte loss, and attenuates glomerulosclerosis in nephropathy models. Thus, inhibiting importin-α–mediated nuclear translocation of dendrin is a potential strategy to halt podocyte loss and glomerulosclerosis.

Background

Nuclear translocation of dendrin is observed in the glomeruli in numerous human renal diseases, but the mechanism remains unknown. This study investigated that mechanism and its consequence in podocytes.

Methods

The effect of dendrin deficiency was studied in adriamycin (ADR) nephropathy model and membrane-associated guanylate kinase inverted 2 (MAGI2) podocyte-specific knockout (MAGI2 podKO) mice. The mechanism and the effect of nuclear translocation of dendrin were studied in podocytes overexpressing full-length dendrin and nuclear localization signal 1–deleted dendrin. Ivermectin was used to inhibit importin-α.

Results

Dendrin ablation reduced albuminuria, podocyte loss, and glomerulosclerosis in ADR-induced nephropathy and MAGI2 podKO mice. Dendrin deficiency also prolonged the lifespan of MAGI2 podKO mice. Nuclear dendrin promoted c-Jun N-terminal kinase phosphorylation that subsequently altered focal adhesion, reducing cell attachment and enhancing apoptosis in cultured podocytes. Classical bipartite nuclear localization signal sequence and importin-α mediate nuclear translocation of dendrin. The inhibition of importin-α/β reduced dendrin nuclear translocation and apoptosis in vitro as well as albuminuria, podocyte loss, and glomerulosclerosis in ADR-induced nephropathy and MAGI2 podKO mice. Importin-α3 colocalized with nuclear dendrin in the glomeruli of FSGS and IgA nephropathy patients.

Conclusions

Nuclear translocation of dendrin promotes cell detachment–induced apoptosis in podocytes. Therefore, inhibiting importin-α–mediated dendrin nuclear translocation is a potential strategy to prevent podocyte loss and glomerulosclerosis.
Psychometric Evaluation of the Adaptation of the Short Form Foreign Language Classroom Anxiety Scale
Authors: KARABULUT Halil İbrahim
Published: May 2023

Foreign Language Classroom Anxiety Scale (FLCAS) has been extensively used as a tool for the measurement of anxiety induced by foreign language learning. Numerous studies employed the scale in different contexts including different native languages, age groups, and national or international samples of varying sizes. FLCAS has also been a topic of interest in studies that investigated its psychometric characteristics, with varying results reported over the years regarding dimensionality, construct validity, and differential item functioning. The inconsistent results in the literature has recently directed efforts towards either developing a new scale or forming a short form to be utilized in language anxiety research. This study aims at contributing to the latter line of research through a psychometric evaluation of the short form of the scale (S-FLCAS), as used by Dewaele and MacIntyre (2014), through the implementation of its Turkish translation in a sample of university students in Turkey. S-FLCAS, which is formed by eight items from the original 33-item scale, was evaluated based on validity and reliability analyses. The results of this study lend support to the efficacious use of S-FLCAS in future studies as a psychometrically valid and reliable tool to measure anxiety caused by foreign language learning
Öğretmen Adaylarının Kopya Çekmeye İlişkin Metaforik Algılarının İncelenmesi
Authors: PEHLİVAN Hülya , MERCAN Gamze
Published: May 2023

Bu çalışmanın amacı, öğretmen adaylarının kopya çekme davranışına yönelik metaforik algılarının incelenmesidir. Araştırmanın amacına yönelik olarak, nitel araştırma yöntemlerinden fenomenoloji yaklaşımı kullanılmıştır. Araştırmanın çalışma grubu Hacettepe Üniversitesi Eğitim Fakültesinde 2019-2020 öğretim yılında öğrenim gören 180 öğretmen adayından oluşmuştur. Araştırmanın veri toplama aracı olarak araştırmanın çalışma grubunun demografik özelliklerini belirlemeye yönelik iki soru (cinsiyet ve bölüm) ve öğretmen adaylarının kopya çekmeye davranışına yönelik metaforik algılarının incelenmesine yönelik görüşlerinin belirlenmesine yönelik iki yarı yapılandırılmış açık uçlu sorudan oluşan görüşme formu kullanılmıştır. Veriler MAXQDA 2018 Programı ile içerik analiz tekniği kullanılarak analiz edilmiştir. Araştırma sonuçlarına göre kopya çekmeye yönelik olumlu bir bakış açısına sahip öğrenciler bunu bir yetenek olarak algılamakta ve zor duruma düştüğünde kullanılacak bir araç olarak düşünmektedir. Kopya çekmeyi bir yardımlaşma aracı olarak düşünen ve adrenalin salgılaması nedeniyle heyecan duymaya sebep olan bir unsur olarak düşünen öğrenci grubu da bulunmaktadır. Bu açıdan ele alındığında öğrencilerin özellikle eğitim fakültesi öğrencilerin çoğunun kopya çekmeyi olumsuz olarak algılaması hem kendileri için hem de eğitim sistemi için olumlu bir unsur olarak düşünülebilir. Ayrıca eğitim fakültesi öğrencilerinin büyük bir bölümünün kopya çeken kişiye yönelik olumsuz bir bakış açısı olduğu görülmüştür. Bu öğretmen adaylarının meslek hayatına atıldığında öğrencilerinin kopya çekmesine izin vermeyeceği ve kaliteli bir öğrenme sağlayacağı düşünülebilir.
Proje Tabanlı Öğrenme Üzerine Gerçekleştirilen Bilimsel Çalışmaların Bibliyometrik Analizi
Authors: KOÇ Adem
Published: May 2023

Bu araştırmanın amacı eğitim alanında proje tabanlı öğrenme yöntemi üzerine gerçekleştirilen bilimsel çalışmaların bibliyometrik analizini gerçekleştirerek bu alandaki genel durumu ve eğilimi açığa çıkarmaya çalışmaktır. Bu bağlamda araştırma, elde edilen verilerin doğası gereği, nitel araştırma yöntemlerinden doküman inceleme yöntemine göre gerçekleştirilmiştir. Araştırmada elde edilen veriler betimsel ve bibliyometrik analiz yöntemleri ile çözümlenmiştir. Araştırma kapsamında WoS veritabanına erişim sağlanarak “Project-based learning” anahtar kavramı başlıkta taranmıştır. Bu bağlamda 09.06.2022 tarihinde gerçekleştirilen taramada eğitim alanında ilgili anahtar kavramı içeren toplam 998 bilimsel çalışma olduğu görülmüştür. Erişim sağlanan bulgular öncelikle WoS veri tabanında betimsel özellikler açısından analiz edilmiştir. Ardından elde edilen veriler kaydedilerek VOSviewer programı yardımıyla da bibliyografik özellikler olarak ifade edilen atıf sayıları, ortak atıf, ortak yazarlık, birlikte bulunma, bibliyografik eşleştirme analiz tipleri bakımından yazar, kurum ve ülkelere göre analiz edilmiştir. Buna göre en fazla bilimsel çalışmanın 2017 yılında yayınlandığı ve yayınların büyük çoğunluğunun İngilizce ve İspanyolca dillerinde olduğu görülmüştür. ABD ve İspanya kaynaklı yayınların çoğunlukta olduğu, alandaki en üretken yazarların Krajcik ve Lou olduğu ve yayınları ile en yüksek atıf sayısına sahip derginin de “Educational Psychologist” olduğu sonucuna ulaşılmıştır. Sonuç olarak araştırmada eğitim alanında proje tabanlı öğrenme yöntemi üzerine gerçekleştirilen bilimsel çalışmaların genel eğilimleri analiz edilerek analiz birimleri çerçevesinde genel durum ortaya konulmaya çalışılmıştır.
Balzac picassiano, un Picasso balzaquiano: Mr Frenhofer and the Minotaur, de Sidney Peterson
Authors: Zambrano Carballo Pablo
Published: May 2023

El artículo analiza el cortometraje Mr Frenhofer and the Minotaur (1949), la singular adaptación surrealista que el director vanguardista norteamericano Sidney Peterson realizó del célebre relato Le Chef-d’œuvre inconnu, de Balzac (1837). Se ofrece primero una somera introducción a los principales elementos del mismo y a la fuerte impronta que ha dejado en la historia del arte. A continuación, se estudian las dos contribuciones más relevantes e innovadoras de la película en su recepción de la historia balzaquiana: por un lado, la fusión con los presupuestos artísticos de Picasso y, por otro, el uso de la anamorfosis como técnica capaz de convertir la propia película en una manifestación del tipo de arte que la crítica y un gran número de artistas han visto preconizado en el relato de Balzac y, particularmente, en la figura y en la enigmática obra del pintor Frenhofer, su protagonista.
DeRisi Lab RNA Library Prep 96-well Protocol on Echo 550 v1
Authors: Y Mayday Madeline
Published: May 2023

Preparation of high-quality sequencing libraries is a costly and time-consuming component of metagenomic next generation sequencing (mNGS). While the overall cost of sequencing has dropped significantly over recent years, the reagents needed to prepare sequencing samples are likely to become the dominant expense in the process. Furthermore, libraries prepared by hand are subject to human variability and needless waste due to limitations of manual pipetting volumes. Reduction of reaction volumes, combined with sub-microliter automated dispensing of reagents without consumable pipette tips, has the potential to provide significant advantages. Here, we describe the integration of several instruments, including the Labcyte Echo 550 acoustic liquid handler and the iSeq and NovaSeq Illumina sequencing platforms, to miniaturize and automate mNGS library preparation, significantly reducing the cost and the time required to prepare samples. Through the use of External RNA Controls Consortium (ERCC) spike-in RNAs, we demonstrated the fidelity of the miniaturized preparation to be equivalent to full volume reactions. Furthermore, detection of viral and microbial species from cell culture and patient samples was also maintained in the miniaturized libraries. This protocol has been optimized for bronchoalveolar lavage fluid (BALF), nasopharyngeal swabs, RNA PAXgene blood, and plasma samples (see protocol variations for sample types needing RNA depletion).
Online Courts and Private and Public Aspects of Open Justice: Enhancing Access to Court or Violating the Right to Privacy?
Authors: Ahmed Sabreen
Published: May 2023

As the technological revolution takes over the world, the justice system is also susceptible to change. The Online Court of England and Wales (‘OC’) is an example of such a step taken in that direction. However, some argue that this has vast implications on access to justice for the ‘digitally excluded’ or the Litigant-in-Persons (LIP). While this argument is warranted, it fails to address the two essential implications of Online Courts: First, the potential of online courts to enhance access to justice by legally empowering LIPs along with enhancing access to court for them (Private Aspect of open justice). Further, such access to court is enhanced for the general public and the media (Public Aspect of open justice) alike. Secondly, the threat of uncontrolled access to online proceedings facilitated by modern avenues like ‘live-streaming’ and ‘live-tweeting’, turning justice into a disruptive one. This article argues that OC is better placed at improving access to justice issues than physical courts, by enhancing both the private and public aspects of open justice. However, enhancing the public aspect also poses major threats to the Right to Privacy of individuals. Further, this article argues that a more nuanced approach towards a future technology-focused justice system needs to balance the public aspect of the open justice principle with the Right to privacy. Hence, this article suggests that regulative and accountability measures like ‘penalty point systems’ should be placed right from the outset to prevent any leakage of sensitive data prompted by uncontrolled access to online courts.
Pharmacists Maintain Consistency and Trust During a Pandemic
Authors: Gatton Ouita
Published: May 2023

Pharmacists, physicians, and nurses have been viewed as needed and trustworthy members of the community for years. During the COVID-19 pandemic, pharmacists’ authority was recognized and expanded to include provi­sion of essential services beyond traditional medication expertise and pharmacy operations. This authority needs to be maintained post-pandemic to provide maximum benefit to patients.
ALTIN ORDA HANLIĞI’NDA KADIN (Ailede, Toplumda ve Yönetimde)
Authors: DERİN PAŞAOĞLU Derya
Published: May 2023

Türk kültüründe; ailede, toplumda, milletin ve devletin içinde kadın ve erkek kıyaslanmayan değerlerdir. Bozkır kültürü ile şekillenmiş ekonominin ve toplum yapısının teşkilatına dayanan Türk devletlerinde, kadın yaşamın her alanında yer almıştır. Öncelikle ailede ve toplumda her zaman bir bireydir. Bir eş, gelecek nesli yetiştiren bir anne, aile ekonomisi için üretici, ailesini halkını milletini koruyan bir savaşçı, devleti yöneten bir hatun ya da hanın ardındaki âkil olma gibi sorumluluklar yüklenmiş ve başarıyla yerine getirmiş zaman zaman da taht kavgalarında taraf olmuştur. Altın Orda Hanlığı, Cengiz Han’ın büyük oğlu Cuçi oğullarınca tesis edilmişse de hâkimiyet sahası olan Deşt-i Kıpçak coğrafyasının kadîm Türk yurdu olması hasebiyle kısa sürede Türk- İslâm kimliğini almış olması dolayısıyla Altın Orda coğrafyasında kadın, Türk-İslâm kimliğiyle karşımıza çıkmaktadır. Yerli kaynakların ve resmi yazışmaların yanı sıra bölgeye ulaşan Carpini, Rubruck ve Battuta gibi seyyahların notları, Altın Orda Hanlığı’nda kadını yaşamın her alanında gözlemleme imkânı sunmaktadır. Çalışmada özellikle Cengiz İmparatorluğu’nun merkez coğrafyasındaki veya İlhanlılardaki kadınlar ve yaşamlarına dair örneklerden yola çıkarak genel söylemler oluşturmaktan kaçınılmıştır. Salt Altın Orda Hanlığı coğrafyasındaki uygulamalar ve örnekler değerlendirilerek Altın Orda Hanlığı’nda kadının statüsü; ailede, toplumda ve yönetimdeki rolleri açısından ele alınmış; söz konusu statünün Türk bozkır kültürü, Cengiz Han’ın yasagları ve İslâm kültürü üzerinde sentezlenerek şekillendiği görülmüştür.
ÇOK PARTİLİ SİYASAL HAYATIN İLK YILLARINDA “TÜRK DEMOKRASİSİ”NİN SAVUNUCUSU OLARAK TRABZON HALKEVİ VE İNAN DERGİSİ
Authors: ATALAY Lemi
Published: May 2023

Cumhuriyetin ilk yıllarında Türk İnkılâbı’nın ideolojisini geniş halk kitlelerine yayma amacıyla kurulan Halkevleri, faaliyet içerisinde bulunduğu süreç boyunca tek parti iktidarının politikalarına uygun hareket etmiş ve Halkevleri şubeleri tarafından çıkarılan dergiler bu politikaların önemli araçları olmuştur. Trabzon Halkevi Şubesi ve onun yayın organı olan İnan dergisi de bu durumun yansıdığı örneklerden biri olup, bu çalışmada özellikle çok partili hayata geçiş sürecinin gerçekleştiği ilk dönem olan 1945-1950 yılları arasında, ülke siyasetinde yaşanan demokratik dönüşümün izlerini Trabzon Halkevi ve İnan dergisi üzerinden sürmek amaçlanmıştır. Bu doğrultuda İnan dergisinde dönem içerisinde demokrasi üzerine çıkan yazılar temel alınarak hareket edilmiş ve bu yazılar hem demokrasi teorisi, hem de dönemin genel iktidar politikaları etrafında değerlendirilmeye çalışılmıştır. Yapılan incelemeler sonucunda, Trabzon Halkevi ve İnan dergisinin ülkedeki demokratik dönüşümden etkilendiği ve iktidarın demokrasi konusuna yaklaşımına uygun bir tutum takınarak, bazı çekincelere sahip olunsa da “Türk demokrasisi” olarak niteledikleri süreci destekledikleri tespit edilmiştir.
TARİHİ SÜREÇ İÇERİSİNDE GEÇMİŞ VE GÜNÜMÜZ KENTSEL MEKÂN KULLANIMI: KALEPARK VE GANİTA ÖRNEĞİ
Authors: DOĞAN Filiz
Published: May 2023

Bu çalışmanın amacı, çeşitli kültürlere ve medeniyetlere ev sahipliği yapmış Trabzon kentini 1900’lü yılların başından günümüze kadar geçen tarihsel süreçte geçmiş ve günümüz kentsel mekan kullanımı bağlamında incelemektir. Bu bağlamda araştırmanın amacı, geçmişten günümüze tarihe tanıklık etmiş Trabzon Güzelhisar mevkii Kalepark ve Ganita mekan kullanımına ait yapılan görüşmeler, geçmiş ve günümüzü yansıtan yazılı anlatımlar, hatıratlar ve görsel belgelerden yararlanılarak kullanıcı memnuniyetini tespit edip değerlendir-mektir. Makalede literatür taraması yapılarak, yazılı ve sözlü verilerden yararlanılmıştır. Çalışma alanına ait daha detaylı bilgi elde edebilmek ve elde edilen verilerin eksik yönlerini tamamlayabilmek amacıyla görüşme yapılması planlanmıştır. Yapılan yüz yüze görüşmeler ile geçmişte sosyal hizmet, barınma ve askerlerin eğitimine hizmet veren, kentin başlıca savunma noktalarından biri olan Kalepark ve onun batı yamacında yer alan, deniz kıyısında günümüzde de varlığını sürdüren Ganita çalışma alanını tanımlayan mekanlar, etkinlikler, geçmiş ve günümüz değerlendirmeler fotoğraflar ve anılar üzerinden kullanı-cıların kendi anlatımlarıyla verilmektedir.
GELENEĞİN YENİDEN KEŞFİ: GÜMÜŞHANE ÖRNEĞİ ÇERÇEVESİNDE ZİYARET YERLERİNİN HASTALIKLARIN TEDAVİSİNDEKİ İŞLEVİ
Authors: YILDIRMIŞ Fatma
Published: May 2023

Zengin bir muhtevayla günümüze kadar gelmiş tedavi yöntemlerini içeren Türk halk hekimliğinin tedavi yöntemlerinden biri ziyaret yerlerine giderek şifa aramaktır. Bütün Türk toplumlarında kutsallığına ve sağaltıcı gücüne inanılan ziyaret yerleri, geçmişte bir tedavi merkezi olarak işlev görmüştür. Oralarda dua etmek, adak adamak, kurban kesmek, mum yakmak, para atmak, bazen bir gece orada uyumak tedavi için uygulanan pratiklerdir. Bu ziyaret yerleri içinde hastalıklara iyi geldiğine inanılan türbeler, yatırlar, su gözeleri, mağaralar, ağaçlar, taşlar, kayalar, tepeler mevcuttur. Anadolu toprakları bu açıdan zengin bir birikime sahiptir.

Halk hekimliği uygulamaları, onları uygulayan insanların ekonomik ve sosyal şartlarının değişmesi ve modern tıbbın gelişmesiyle ikinci plana atılmıştır. Fakat geleneksel tıbba olan ihtiyaç tekrar artınca geleneğin yeniden keşfi gündeme gelmiştir. Bu makalede örneklem olarak Gümüşhane ve ilçeleri seçilmiş, örneklem içerisindeki ziyaret yerleri tespit edilerek hangi hastalığa tedavi olarak hangilerinin tercih edildiği incelenmiştir. Makalede gözlem, görüşme, kılavuz ve kaynak kişilerden bilgi toplama yöntemleri ve literatür taraması kullanılmıştır.
OSMANLI DÖNEMİNDE KARADENİZ ŞEHİRLERİNDE SİGORTALI İŞLEMLER VE SİGORTA ŞİRKETLERİNİN AKTİVİTELERİ
Authors: ÖZGER Yunus
Published: May 2023

Dünyada sigortacılık, uluslararası ticaretle paralel gelişim gösterdi. İlk olarak liman şehirlerinde ortaya çıktı daha sonra iç bölgelerdeki şehirlere de yayıldı. Sigortacılığın Türkiye’deki gelişimi de aynıdır. Kapalı bir iç deniz olan Karadeniz, 1774 tarihli Küçük Kaynarca Antlaşması sonrasında ticari yönden ivme kazandı. Bölgede artan ticaret, sigortacılığı da beraberinde getirdi. Osmanlı coğrafyasında sigortacılığa rağbet, 1853-1856 Kırım Savaşı sonrasında arttı. Ancak bu tarihten önce de deniz nakliyatında sigortalı işlemlere tesadüf edilmektedir. Karadeniz’de en eski tarihli sigortalı nakliyat işlemi şimdilik 1789 tarihlidir.

Bu çalışmada Samsun, Trabzon, Sinop, Ordu gibi denize kıyısı olanlarla birlikte Amasya ve Tokat gibi iç bölgelerdeki Karadeniz şehirlerinde sigortacılık faaliyetleri incelendi. Bu bağlamda bölgede işlem yapan yabancı sigorta şirketleri hakkında bilgi verildi. Sigorta şirketlerinin bölgedeki rekabetleri konusu ele alındı. Bölgede kamuya ait yapıların sigortalanma süreçleri üzerinde duruldu. Kasıtlı yangınlar ve bunların sigorta şirketleriyle bağlantısı iddiaları ele alındı.
An uncommon presentation of filariasis: A case report
Authors: Kesavan T M Ananda , Narayan Amrutha , Rose Freena
Published: May 2023

Filariasis continues to be a very important public health problem plaguing India. This is a tropical disease, caused primarily by Wuchereria bancrofti and few caused by Brugia malayi. Even though the prevalence of filariasis is high, it is rarely reported from the lymph nodes. We would like to report the case of a 2-year-old boy who presented with a right sided post-auricular swelling of size 2 x 2 cm since past 1 year. Routine blood investigations including peripheral smear was reported as normal. FNAC from the lymph node revealed microfilaria. This case report is to highlight the chances of finding microfilaria from an unsual site.
The U.S.-Japan Cooperation as part of the Fumio Kishida’s renewed administration strategy
Authors: Motyavin Michael
Published: May 2023

The article outlines the changes in Japan's strategy under the Fumio Kishida’s administration and the areas of interaction with Washington within the framework of Tokyo's new policy. The military, economic, technological and space areas are analyzed.
Bing Crosby – 120 years later
Authors: Popov Nikolay
Published: May 2023

The article is devoted to the analysis of the creative heritage and the role in the cultural life of the USA of the famous vocalist, film actor and creator of the musical style Bing Crosby. His role in the development of the country's musical culture, musical cinema and radio broadcasting, his influence on American and world popular music is considered.
Russia, the USA and the Arctic. Part 2. Conflicts and the new arms race
Authors: Rogov Sergey
Published: May 2023

The article is devoted to the analysis of the primary background issues for the growth of the conflict potential of the US-Russia relations in the Arctic region. The author focuses on the competition for control over the Arctic continental shelf. The Arctic Council has been paralyzed since the start of a special emergency operation. The confrontation in the Northern Sea Route between Russia and the USA, advocating «freedom of navigation», is considered. The article analyses doctrinal documents of Russia and the United States and evaluates the military history of the Arctic region and the arms race launched by NATO in the Arctic. Russian defense response is briefly described.
Technical optimism theoretical limits
Authors: Rodionov D. A.
Published: May 2023

This work reveals a part of the technical optimism theoretical limits. The aim of the study is to represent the technical optimism as a modification of a spontaneous value mindset and to reveal the main theoretical limits of it. In this regard, the main categories of the technical optimism are described as a phenomenon (engineering as the wheal a priori, assertion of the engineering orientation to obtain benefits, technical reality acceptance), the technology axiological neutrality is identified and substantiated. The essence of the technical singularity is revealed as one of the options for describing the limit of the scientific and technological progress, and as one of the main modern optimistic technology concepts. The basic aspects of the epistemic and existential modalities of the technical optimism are revealed, that allows to see the basis of the technical reality axiological thematization. The main research methods are idiographic and nomothetic methods. The study is novel in that it identifies the technical optimism modalities.
Semiotics of the city in the sketches by N. Garin-Mikhailovsky «In the hustle and bustle of the provincial life»
Authors: Perepelkin Mikhail A.
Published: May 2023

This article attempts to analyze the semiotics of the urban space depicted by N. Garin-Mikhailovsky in In the hustle and bustle of the provincial life sketches. For this purpose, the main city locations, described by the author, are identified - the noble assembly, the governor's house, the apartments of the photographer and Abramson, Khlebnaya Square and some others. On the basis of the analysis, it is concluded that, when sketching a portrait of the city, Garin depicts it in almost the entire geographical extent - from the southwest to its northeastern outskirts; the intention to show the whole Samara in terms of the geographical extent is accompanied with a similar intention to show different social levels of the city life; urban locations are not depicted as static, remote and isolated objects, but as connected by a wide variety of connections and relationships. All this together allows us to consider the city, depicted in N. Garin-Mikhailovskys sketches, as a semiotic structure, a complex meaning, and decoding is the only way to get closer to a real understanding of the formula in the title of the cycle In the hustle and bustle of the provincial life.
Turismo e patrimônio no município de Ouro Preto/MG: desigualdades territoriais e contradições socioespaciais circundantes aos valores históricoculturais
Authors: Ferreira Erick Alan Moreira , Teixeira-da-Silva Rafael H.
Published: May 2023

Ouro Preto é reconhecida nacional e internacionalmente por seu valor patrimonial e histórico materializado na monumentalidade das construções do período barroco-colonial. Estes fatores levaram a cidade a ser consagrada enquanto Patrimônio Mundial da UNESCO em 1980. A chancela da UNESCO permitiu que a cidade conquistasse mais renda diante do fluxo de capital em razão do reconhecimento de valores como singularidade, autenticidade e excepcionalidade. Nesse contexto, o objetivo da pesquisa é debater a relação conflituosa entre turismo e patrimônio, tecendo conexões com as motivações políticas, institucionais e econômicas que estão no entorno da sua preservação. Destarte, foi realizada uma pesquisa descritiva e exploratória que encaminhou-se por meio de técnicas de pesquisa bibliográfica e análise documental para efetivar a interpretação e a discussão dos resultados. O estudo foi construído a partir de dezenas de artigos científicos, trabalhos publicados em anais de eventos, capítulos de livros, dissertações e teses de doutorado, buscando aprofundar o conhecimento acerca das características que abarcam o objeto de investigação . Ao final foram perceptíveis as contradições socioespaciais e territoriais reveladas na relação do turismo com o patrimônio , pois ao passo que a municipalidade se aproxima do centro histórico, ela distancia-se das periferias. O processo de refuncionalização turística do centro histórico foi concebido priorizando os valores mercadológicos, prevalecendo a cenarização e a fetichização da paisagem como forma de atrair turistas. Espera-se que o poder local e as resistências sociais instituam instrumentos de enfrentamento úteis frente ao processo de segregação socioespacial, prezando pela manutenção de espaços multifuncionais voltados à fruição e à apropriação efetiva do patrimônio. Além disso, vislumbra-se uma política urbana mais justa, com foco em uma política patrimonial baseada na gestão participativa dos núcleos urbanos tombados. Há ainda a necessidade de ativar memórias que sejam integradoras, que estimulem o diálogo, que permitam escapar de imposições historicamente estabelecidas. Da mesma forma, é necessário suprir a carência de patrimônios identificados em todos os setores territoriais da cidade, sobretudo nos espaços marginais e não somente nos que estão localizados em seu centro histórico.
Editorial
Authors: Sanchez Edney , Botelho Eloise Silveira , Barcelos Fernanda , Belem Ivone
Published: May 2023

Editorial