bluuebunny/crossref_metadata_2025 huggingface dataset:
Emergence of human infections with the novel avian influenza in Zhejiang Province, China post COVID-19 pandemic: An epidemiological analysis
Authors: Wang Xiaoxiao , Mao Haiyan , Kong Lingjie , Xu Zenghao , Ren Jiangping , Sun Zhou , Shou Jun , Pang Zhifeng , Sun Yi , Lou Xiuyu , Su Lingxuan , Huang Chen , Sun Jimin , Ling Feng , Jiang Jianmin , Chen Zhiping
Published: November 2024

Avian influenza viruses (AIVs) continue to pose a significant public health threat globally, particularly after the COVID-19 pandemic. Between January 2020 and January 2024, four human cases of AIV infection were reported in Zhejiang Province, China, raising concerns about the emergence of novel strains. A 63-year-old woman from Anhui Province became the first globally reported case of AIV H10N5 infection, likely contracted while slaughtering live ducks. In June 2022, a 33-year-old man from Zhejiang Province was confirmed as first case of AIV H10N3 in Zhejiang Province and the second case globally. Additionally, two women, aged 51 and 55, were confirmed to have AIV H5N6 infection in December 2021, with no epidemiological links between them. Their infections were likely caused by exposure to infected or contaminated poultry during unprotected cleaning and processing activities. Except for H10N5 patient who died, the other three patients recovered after antiviral treatment with oseltamivir. Epidemiological investigations and genomic analysis confirmed avian origins for these cases. These cases underscore the ongoing risk posed by novel AIV strains, particularly in environments where there is direct or indirect contact with infected birds, such as wet markets or poultry processing facilities. Continuous surveillance, improved monitoring, and stricter protocols for poultry handling and processing are crucial to reducing the risk of human exposure to these viruses. This study emphasizes the need for enhanced preventive measures to mitigate the potential for future outbreaks of AIV in humans.
Portrait of a series of patients with pheochromocytoma/paraganglioma from a reference center in Brazil: Relevance of prior background features
Authors: Lima José Viana , Scalissi Nilza M. , Goldman Suzan M. , Kater Claudio E.
Published: November 2024

Context: Pheochromocytomas (Pheo) and paragangliomas (PGL) (PPGL) are catecholamine-producing tumours, whose functionality is confirmed by elevated plasma (Pl) and/or 24-h urinary (Ur) metanephrines (MN).
Objective/Design: We review clinical, hormonal, and imaging aspects of 116 patients studied prospectively: 93 Pheo, 22 PGL, and one Pheo plus PGL.
Results: Twenty-five % PPGL were discovered incidentally. Systemic arterial hypertension (SAH) was present in 81% (43% on stage 3), whereas 9.5% were prehypertensiveand 9.5%, normotensive. SAH plus paroxysms occurred in 31 (33%) patients, being exclusively sustained in the remaining; 26 (28%) had resistant SAH. Orthostatic hypotension was present in 65% of patients. Pl/Ur MN and normetanephrine (NMN) were compared to those of a positive (56 functioning PPGL) and a negative control group (654 subjects with normal MN/NMN). Total and fractionated Ur MN were elevated in 94% PPGL patients. Cut-off values of 885 mcg/24-h for Ur MN, and of 1.5 nmol/L for Pl MN identified functioning lesions with 100%/100% sensitivity and 93%/97% specificity, respectively. MRI detected 56% Pheo on the right side,25% on the left, and 19% bilateral; 13 of 23 PGL (56.5%) were retroperitoneal and 10 (43.5%), cervical. Right-side Pheo were larger (5.8 cm) than left-side ones (3.7 cm), but retroperitoneal (6.5 cm) and neck PGL (6.9 cm) were similar in size. Tumour size positively correlated with total Ur MN.
Conclusions: in this large cohort of PPGL patients we highlighted relevant aspects of SAH, the frequentlyoverlooked manifestation of orthostatic hypotension, common incidental presentation, and significant tumour size/hormonal production correlation.
Research on hydrodynamic characteristics of a floating horizontal axis tidal turbine considering wave and platform motion
Authors: Mei Yunlei , Jing Fengmei , Wang Xinru , Guo Bin , Lu Qiang
Published: November 2024

The floating horizontal-axis tidal turbine (FHATT) stands out as the most commercially viable tidal energy device. This paper reviews recent literature on FHATT and summarizes experimental and computational fluid dynamics (CFD) methods employed in FHATT research. Based on this foundation, the coupling effects of wave and platform motion (pitch/roll) on FHATT hydrodynamic performance were investigated through flume experiments and CFD simulations. The variations of the power coefficient (CP) and thrust coefficient (CT) are analyzed under different platform motion periods, amplitudes, wave periods, and wave heights. The results demonstrate that under the coupling of waves and pitch motion, CP and CT exhibit dual-frequency oscillations based on the pitch period, with oscillation amplitudes increasing with both pitch frequency (wave frequency) and pitch amplitude (wave height). Within the working conditions of this study, the maximum mean output power under the coupling of pitch motion and waves increases by 26.1%. The maximum fluctuation amplitude of CP reaches 349.8%. When waves and roll motion are coupled, wave parameters dominate, while the influence of roll motion can be ignored. Moreover, the hydrodynamic fluctuations induced by waves and platform motion can couple with each other. This coupling effect not only amplifies the fluctuation amplitude of hydrodynamic coefficients but also has the potential to offset each other. These findings provide insights into the structural design and system control of FHATT, serving as valuable references for FHATT development.
Fathers Role in Infant Feeding and Care: Exploring Perceptions, Practices, And Challenges in Lesotho’s Rural Communities
Authors: Kaloro Kaloro , Mahlelehlele Bokang , TURKSON Rose Kokui Dufe
Published: November 2024

BACKGROUND: Few studies have been conducted that considered the fathers’ role in proper nutrition of infants and young children. Mothers are the ones perceived to offer optimal care and feeding to infants while fathers are often responsible for the income related support especially in low-income class families. Therefore, this study was intended to find out to what degree fathers were involved in infants’ care and feeding.
AIM: The study was aimed at investigating perceptions, practices, and challenges of fathers in infancy (1-12 months) care and feeding.
METHOD: A qualitative study was conducted in Ha Mafefooane village in Roma, Maseru district of Lesotho. Six fathers, who had children between 1-12 months, participated in the study. Individual interviews in Sesotho language were carried out. Thematic analysis was adopted to identify emerged themes from the data.
RESULTS: The study showed that, traditional fathers are partially involved in infants’ care and feeding. Based on their perceptions, practices, and challenges of everyday infants’ care and feeding, fathers perceive routine child care and feeding as mothers’ duty and they only get involved as the way of assisting mothers as well as income generation. The findings showed that fathers lack knowledge of their role in child care and feeding practices.
CONCLUSION: This study helped to reveal the perception, practice and challenges of fathers with respect to the care, infant feeding. Fathers generally think that their role is to provide money for the house, while it is the duty of the mother to take care of the child by feeding and caring. The findings of this study suggest that educating fathers could raise awareness of their importance in infants’ care thus ensuring optimal infants’ feeding, growth and development.
Projected changes in seasonal and monthly atmospheric near surface parameters over West Africa from simulations of CORDEX-CORE ensemble
Authors: Lenouo Andre , Weber Torsten , Tamoffo Alain T. , Hoffmann Peter , Langendijk Gaby S. , Betant Carine , Um Alphonse Um , Meukaleuni Cyrille , Efon Eric , Djiondo Rinelle N.
Published: November 2024

Surface-to-near-surface atmospheric fluxes are essential to improve our understanding of their interactions. Evaluating their evolution allows for advancing climate applications. This study examines the seasonal and monthly Atmospheric Near Surface Parameters (ANSP) over West Africa during the early (2030–2060) and late (2071–2099) periods of the 21st century, considering the representative concentration pathways RCP 2.6 and RCP 8.5. We utilise nine experiments resulting from dynamically downscaling at ~25 km horizontal resolution, of three general circulation models (GCMs) by the means of three regional climate models (RCMs) participating in the Coordinated Regional Climate Downscaling Experiment – Coordinated Output for Regional Evaluations (CORDEX-CORE) initiative. The analysed ANSP includes mean temperature and relative humidity at 2 metres, precipitation and wind speed at 10 metres above the surface. To offer a comprehensive overview of the nine model experiments, we also present and compare the results of their ensemble mean against the reanalysis ERA5 used as reference over the period 1971-2000 for temperature, humidity and wind speed. Furthermore, we also used the rainfall data from Climate Hazards Group InfraRed Precipitation with Station version 2 (CHIRPS2) over the historical period (1983–2005). In general, the results show that the ensemble mean of the model experiments adequately simulates ANSP over West Africa over the historical period. The climate projections reveal an increase in seasonal 2-metre mean temperatures up to 5°C in September-October-November and June-July-August seasons during the last 30 years of the century over the Sahara Desert. Changes in 2-metre relative humidity during the period 2031-2060 are expected to reach 10% between 10°-15°N in the rainy and dry seasons. Meanwhile, changes in 10-metre wind and precipitation are projected to be less than 1 m/s and 1mm/day respectively across the entirety of West Africa.
In-vitro comparisons of African swine fever virus isolates from Uganda reveal similar genetic identity and titer amounts
Authors: Mulondo Samuel , Ezinga Richard , Kabaka Richard Mumali , Abila Patrick P’Odyek , Semakula Jimmy , Ssekiziyivu Rogers , Owila Godious , Anjero Byansi , Kiplangat Joshua , Dhikusooka Moses Tefula , Mugerwa Swidiq , Majalija Samuel , Kabuuka Tonny
Published: November 2024

Background
African swine fever (ASF) is a highly contagious hemorrhagic fever affecting both domestic and wild pigs. It is endemic in sub-Saharan Africa with frequent outbreaks in Eastern and Central Africa. This disease is a threat to the pig industry causing a huge economic impact through pig deaths, failure to export pork or pork products and expenses incurred in its control and prevention.
Methods
Using plaque counts in 6 well cell culture plates, we determined titers of 5 old field viruses namely UG-P9C, UG-SOR36, UG-SQ517B, UG-KAS04, and UG-BUN05 isolated by Kabuuka et al, 2024, and one new field strain UG-P3E.
Results
Sucrose purification of virus isolates resulted in higher titer yields in comparison to supernatant-derived titers. High titers of up to 8.0 x 10− 8 pfu/ml, a log higher than the usual recommended commercial vaccine titer requirements of 1.0 x 10− 7 pfu/ml were registered for some isolates. Further partial genome sequencing of the p72 gene of ASF indicated that all six isolates belong to genotype IX of African swine fever viruses. This study therefore presents scientific evidence that ASF viruses in Uganda are majorly genotype IX, and these have sufficient titers for further vaccine development work.
Failure Analysis of Advanced Ceramics using Bivariate Weibull Distribution and Bayesian Estimation
Authors: Hajizadeh Pouria , Khosravi Mostafa , Ravandi Mohammad
Published: November 2024

This research paper presents a comprehensive study on modeling the failure behavior of advanced ceramics by integrating phenomenological and physics-based approaches. The proposed methodology utilizes the bivariate Weibull distribution to capture the complex failure mechanisms in advanced ceramics, considering the impact of Subcritical Crack Growth (SCG). Approximate Bayesian Computation (ABC) is employed for parameter estimation, leveraging Metropolis-Hastings (MH) and Hamiltonian Monte Carlo (HMC) algorithms to enhance computational efficiency. The study validates the proposed models against a physics-based Batdorf theory approach using NASA’s CARES/Life. Results demonstrate the robustness of the ABC MH and ABC HMC models, highlighting the capability of statistical approach to predict failure dynamics in advanced ceramics under varying conditions. This research contributes to a deeper understanding of advanced ceramic failure mechanisms, paving the way for further advancements in material science and engineering applications of ceramics.
Prevalence and Perception of Premature Ejaculation in Algeria: A Retrospective Cross-Sectional Survey
Authors: BOURAS SAMIR , Yebdri samir
Published: November 2024

Background
Premature ejaculation (PE) is a prevalent sexual dysfunction in men. Despite its significant impact, it remains underreported in the Maghreb countries, particularly in Algeria, due to cultural taboos. This study aims to provide essential epidemiological data on PE in this region.
Methods
A prevalence survey was conducted in January 2024 in the urology department, involving 120 men and 18 women. Participants completed a questionnaire addressing the prevalence of PE, its effects on sexual satisfaction, and perceptions within the couple. Several variables were analyzed to identify potential correlations.
Results
PE was reported by 42% of men and 22% of women regarding their partners, with an intravaginal ejaculation latency time (IELT) ≤ 2 minutes reported by 39.2% of men and 27.7% of women. Incidence increased to 45% among men over 50. The median IELT was 3.5 minutes overall and 1.5 minutes among those with PE. No significant correlation was found between age, sexual frequency, sexual satisfaction, and PE, though significant associations with erectile dysfunction and lower urinary tract symptoms were identified.
Conclusion
The prevalence of PE shows considerable variability, ranging from 4–75%, and tends to increase with age. To our knowledge, this is the first epidemiological study on PE in Algeria and potentially the Maghreb. It underscores the importance of increased awareness and targeted management strategies to improve sexual health and quality of life for affected individuals
Simulation Environment for Reconfigurable Virtual Accelerators Using a Field Programmable Gate Array Development Environment
Authors: Kawai Shunya , Maeda Eriko , Yaguchi Kazuki , Osana Yasunori , Miyoshi Takefumi , Nakajo Hironori
Published: November 2024

In recent years, studies on artificial intelligence and high-performance computing have accelerated computations using field programmable gate arrays (FPGAs). High-Level Synthesis (HLS) is beneficial for implementing algorithms from these fields onto FPGAs as circuits. However, because the circuits generated by HLS are generally larger than those designed with hardware description language, using FPGAs in practice presents challenges regarding resource restrictions. To address these issues, we proposed a Reconfigurable Virtual Accelerator (ReVA), that allows the sharing of resources across multiple FPGAs and enables the implementation of large-scale circuits. In this study, we proposed and implemented a ReVA Simulator. Furthermore, we estimated the execution time when utilizing ReVA and performed evaluations. The evaluation results demonstrate that the ReVA Simulator achieves a fast Fourier transform reduced by 36% compared to execution in C.
Comparative study on different endoscopic submucosal dissection techniques for the treatment of superficial esophageal cancer and precancerous lesions
Authors: Jiang Shuanghong , Luo Zichen , Liu Xiuyu , Guo Haiyang , Cui Yutong , Liang Shiqi , Chen Xinrui , Zuo Ji , Wang Xianfei
Published: November 2024

Background
This study aims to compare the effectiveness and safety of traditional endoscopic submucosal dissection (ESD), endoscopic submucosal tunneling dissection (ESTD), and endoscopic submucosal dissection with C-shaped incision (ESD-C) in the treatment of superficial esophageal cancer and precancerous lesions, providing reference and guidance for the treatment of esophageal cancer.
Methods
A retrospective analysis was conducted on the clinical data of patients who underwent ESD (n = 96), ESTD (n = 103), and ESD-C (n = 98) for superficial esophageal cancer or precancerous lesions between January 2017 and December 2022. Through comparative analysis, the effectiveness and safety of the three surgical methods were evaluated, and the risk factors for postoperative esophageal stricture were explored.
Results
In terms of total operative time and dissection time, the ESD group > ESTD group > ESD-C group; in terms of dissection speed, the ESD group < ESTD group < ESD-C group; in terms of dissection area, the ESD group < ESTD group and ESD-C group; and in terms of wound treatment time, the ESD group > ESTD group and ESD-C group. In terms of surgical outcomes, the en bloc resection rate was 100% in all three groups, with curative resection rates of 86.46%, 90.29%, and 87.76% in the ESD, ESTD, and ESD-C groups, respectively. The incidence of stricture was higher in the ESTD and ESD-C groups than in the ESD group. The risk factors for postoperative esophageal stricture included dissection area, circumferential proportion of the lesion, and injury to the muscularis propria.
Conclusion
ESD, ESTD, and ESD-C are all safe and effective methods for the treatment of superficial esophageal cancer and precancerous lesions. Among them, ESD-C demonstrates advantages over ESTD and ESD in terms of operative time, lesion resection speed, and surgical efficiency. With increasing circumferential proportion of the lesion, larger dissection area, and injury to the muscularis propria during surgery, the risk of postoperative esophageal stricture also increases accordingly.
Barriers and Enablers to the Implementation of Integration Models of Medical and Elderly Care Services in China: A Qualitative Study Using the Theoretical Domains Framework
Authors: Ye Li , Wu Jingyi , Li Kaijun , Sheng Pianpian , Ji Siyuan , Ye Minghua
Published: November 2024

Background Amidst China's rapid demographic aging,the government has initiated the integration of medical and elderly care services,with general practitioners (GPs) at the forefront.This study aims to investigate the perceptions of GPs regarding the barriers and enablers to the implementation of integration models in medical and elderly care services within the Chinese healthcare system.
Methods A qualitative study design was employed and semi-structured interviews were conducted with 23 general practitioners involved in primary and integrated healthcare.We utilized constructs from the Theoretical Domains Framework (TDF) to guide data collection and analysis,examining current practices and identifying key factors perceived to influence the implementation of integrated medical and elderly care services.Two researchers independently coded transcripts into predefined themes using deductive thematic analysis.
Results The barriers and enablers perceived by general practitioners were primarily categorized within eight TDF domains. Key barriers included: knowledge and skill deficiencies among general practitioners (GPs); absence of incentives; insufficient personnel; time constraints;traditional concept in elderly care. Additionalbarriers included unclear service provider roles, uneven distribution of resources, Underutilization of technology. In contrast,perceived enablers included: Sustained policy support; Comprehensive personnel training; innovation in service models; technological advancement.
Conclusions The utilization of the TDF provided a comprehensive insight into the barriers and enablers to the implementation of integrated medical and elderly care services, and consequently, has given direction to future interventions strategies aimed at enhancing the quality and effectiveness of this services.
Epitulipinolide diepoxide induces apoptosis in bladder cancer cells by inhibiting the ERK/MAPK signaling pathway and promoting autophagy
Authors: jing zhiqiang , li kai , feng shuang , su hao , yuan dongbo , zhu jianguo
Published: November 2024

Purpse: Epitulipinolide diepoxide has antitumor effects through previous studies, and this paper describes that Epitulipinolide diepoxide inhibits the proliferation of bladder cancer cells and reveals its mechanism.
Methods: Bladder cancer cells (T24) were treated with different concentrations of Epitulipinolide diepoxide, and the IC50 was determined at 24, 48, and 72 h. The proliferation, apoptosis, migration, and invasion activities of the cells were assessed by CCK-8, clone formation, flow cytometry, Transwell, and scratch assay. Cell proliferation, apoptosis, migration, and invasion activities were assessed The Epitulipinolide diepoxide-target-pathway network was investigated by network pharmacology, molecular docking, enrichment analysis, kinetic simulation, and further confirmed by kinetic simulation of Epitulipinolide diepoxide-target binding, and Western blot to evaluate the ERK/MAPK pathway (ERK/PERK/JUK/PAPK) and the protein levels of autophagy markers (LC3/ATG5/P62) were measured by Western blot to evaluate autophagy. Chloroquine (Chq), an autophagy inhibitor, was used to validate the role of autophagy in the mechanisms regulating Epitulipinolide diepoxide regulation of cell behavior in T24 cells, and a combination of ERK agonists (C16-PAF) was used to explore the involvement of this pathway.
Results: Epitulipinolide diepoxide significantly inhibited the proliferation, invasion, and scratch healing of T24 cells.After Epitulipinolide diepoxide acted on T24 cells, the levels of ERK, JUK, and P38 in the ERK/MAPK pathway were decreased and the level of PERK protein was increased, and the levels of LC3 and ATG5 in autophagy proteins were decreased, resulting in accelerated apoptosis of T24 cells. CHq and C16-PAF partially reversed the Epitulipinolide diepoxide-mediated malignant behavior in T24 cells.
Effect of Ultrasound Treatment on Structural and Physical Properties of Native Maize Starch
Authors: PARRA ESTEBAN JOSUE CARRILLO , Palavecino Pablo , Ribotta Pablo Daniel , Penci Maria Cecilia
Published: November 2024

The focus of this work was to evaluate the differences between the thermal and mechanical energy generated by ultrasound waves on the properties of corn starch, which facilitate the subsequent enzymatic hydrolysis for the generation of porous starches. The results showed that both the thermal and mechanical effects have the capacity to disorganize/alter the structure of starch, impacting on its properties. Characteristics such as particle size, pasting and thermal properties of starch and water absorption were the most affected, while crystallinity was practically unmodified. The thermal effect induced by the ultrasound treatment caused most of the alterations in the properties of corn starch. It was associated with the partial gelatinization of the material due to an increase in the system's temperature. The effect of the mechanical phenomenon of the treatment by ultrasound waves contributed to a lesser extent compared to the thermal effect. The mechanical effect can extend over time, without the aggravating factor of causing starch gelatinization. The combination of both effects could synergistically modify the granular structure of starch. In conclusion, ultrasound waves as a pre-treatment to enzymatic hydrolysis can cause structural disorganization of starch granules and facilitate the subsequent enzymatic attack for the production of porous starches.
Endometriosis and its effects on workplace absenteeism and presenteeism: disrupting inequality regimes
Authors: Howe Danielle , O'Shea Michelle , Duffy Sarah , Eathorne Allie , Armour Mike
Published: November 2024

Endometriosis symptoms, including persistent pelvic pain and fatigue, profoundly affect many people’s ability to undertake paid employment, globally the condition affects between 10-14% of women/those presumed female at birth. Despite its prevalence there is a paucity of research examining supports that might help employees manage their symptoms. The present research investigates how employee endometriosis symptom management shapes workplace presenteeism and absenteeism; while also problematising the organisational practices strengthening inequities for this employee cohort. Individuals engaged in paid employment in Australia (389 respondents) with a self-reported endometriosis diagnosis completed an online survey. Data collected included demographics, symptom experiences, treatment preferences, impacts of endometriosis on work/ career trajectory and disclosure experiences. Results showed that endometriosis symptoms negatively shape absenteeism, presenteeism and career trajectories. Workplace flexibility (hybrid work, breaks, bathroom amenity use) and supportive managers contributed to enhanced productivity (reduced absenteeism and improved presenteeism). Overall, age was the most significant factor influencing absenteeism (P=0.007) and presenteeism (P=0.001), with younger employees reporting greater workplace impacts. Implementing guidelines that prioritise flexibility and inform/educate managers on workplace supports, and challenging the workplace norms (re)producing inequality regimes (discriminating against people with endometriosis based on their gender and ability) emerged as effectual strategies increasing workplace productivity and wellbeing.
Predicting Mean Depth and Area Fraction of Antarctic Supraglacial Melt Lakes with Physics-Based Parameterizations
Authors: Grau Danielle , Hussain Azeez , Robel Alexander
Published: November 2024

Supraglacial melt lakes have been implicated in decreasing albedo and increasing flow speed of the Greenland Ice Sheet and ice shelf disintegration in Antarctica. However, supraglacial melt lakes are largely not represented in current large-scale climate and ice sheet models due to their small size compared to typical model grid spacing. In this study, we first use extensive surface elevation measurements from the ICESat-2 satellite altimetry mission to show that roughness on the Antarctic Ice Sheet surface is largely self-affine, consistent with prior observations of bed roughness beneath ice sheets and geomorphic surfaces more broadly. This self-similarity of ice sheet surfaces across scales enables us to develop a broadly applicable set of simple mathematical expressions parameterizing the average supraglacial melt lake area fraction and lake depth. These parameterizations depend only on two ice sheet roughness parameters and the depth of water supplied as runoff from the surface melt. We derive these parameterizations from statistical fitting of large Monte Carlo ensembles of numerical simulations of water flow on random, self-affine surfaces and show that they provide predictions that are generally consistent with observations. Finally, we predict that on large portions of Antarctic ice shelves supraglacial lakes are likely to, on average, stay less than one meter deep and occupy less than 40% of the ice area, absent changes in ice shelf surface roughness.
Novel Approach for Enhanced Ransomware Detection: Introducing Adaptive Pattern Signature Analysis
Authors: Gromov Frances , Ferreira Julian , Lombardi Patrick , Grigori Samuel
Published: November 2024

The escalating sophistication and frequency of ransomware attacks have rendered traditional detection methods increasingly inadequate, necessitating the development of more adaptive and intelligent security solutions. Adaptive Pattern Signature Analysis (APSA) emerges as a novel framework that dynamically generates and adjusts behavioral signatures in real-time, thereby enhancing detection accuracy and adaptability to evolving ransomware tactics. APSA's architecture integrates advanced pattern recognition techniques with adaptive matching mechanisms, enabling the system to identify and respond to previously unseen ransomware behaviors with minimal latency. Comprehensive evaluations demonstrate APSA's superior performance in detection accuracy, reduced false positive rates, and scalability across diverse operational environments. These findings demonstrate APSA's potential to significantly advance ransomware detection technologies, offering a robust and flexible approach to mitigating the impact of sophisticated cyber threats.
Mental Health and Mental Disorders
Authors: McCord Carly E. , Phillips Reindel Kala M. , Sopchak Kelly , Stickley Mariah , Williamson Meredith
Published: November 2024

Addressing mental health needs is a clear priority for rural constituents. Issues of accessibility, availability, and acceptability of mental health care in rural areas are well documented. There are viable solutions for improvement as evidenced by the percentage of federally designated MHPSAs in rural or partially rural areas dropping from more than 85% to just under 68% since the 2015 publication of RHP 2020. The use of screening tools for anxiety and depression and the continued integration of mental/behavioral health care within primary care, coupled with intentional focus on training health professionals across disciplines in these models will positively benefit rural areas. Telehealth has a critical role in addressing the mental health crisis and can be used across the lifespan in a variety of settings including homes, schools, community centers, and medical facilities. Thinking outside the medical system by including peer support, utilizing evidence-based models for suicide prevention and mental health awareness, and capitalizing on extended support from community mental health workers will further increase access. Particular attention should be paid to those experiencing the greatest disparities in access and outcomes such as youth, LGBT individuals, and individuals with disabilities
An Examination of the Workforce in Rural America
Authors: Brandford Arica , Falia Gogoal , Fahrenwald Nancy , Clark Heather , Bolin Jane N. , Rigsby Matilin , Kolade Fiyinfolu
Published: November 2024

It is important to leverage the healthcare workforce in new and innovative ways, with more care taking place outside of traditional settings. Flexibility in the way individuals connect with and engage in care is critical. Relationships are central to the development, forward progress, and collective action of community-based partnerships and collaborations. Often, evaluation of partnerships or community collaborative efforts focuses on achieving outcomes and effectiveness; however, community capacity building has many dimensions including: skills and resources, nature of social relations, structures and mechanisms for community dialogue, civic participation, value systems, and learning culture. Continued expansion of telehealth as a means of healthcare provision means identifying evidence-based practices and policy changes to address challenges. There is a need to improve the quality and standardization of data to fully demonstrate and understand the impact of telehealth and identify where disparities persist. Telehealth plays a key role in helping to address workforce issues by enhancing access and reducing burnout.
Rural Health Issues in Child and Adolescent Development
Authors: Wilson Kelly
Published: November 2024

The Rural Healthy People 2030 survey ranked “Child and Adolescent Development” as a top 20 health priority, emphasizing the need for specialized attention to rural youth. This demographic faces higher health and developmental risks than urban peers. Key areas requiring targeted efforts include education, literacy, healthcare access, and mental health services. These are vital for improving the health and development of rural children and adolescents. Ongoing monitoring of health trends and the effectiveness of evidence-based programs in rural settings is essential. Such surveillance will enhance health outcomes and provide insights into the utilization of resources by rural youth. Understanding the complex challenges faced by rural children, particularly those with multiple risk factors, is crucial as they transition into adulthood. This knowledge is imperative for shaping interventions that cater to the evolving needs of this growing population.
The Issue of Chronic Pain in Rural America
Authors: Williamson Brandon , Woodland Gracie
Published: November 2024

Chronic pain remains a devastatingly common disease in the U.S., with higher prevalence and greater severity in rural areas. Treatment of chronic pain in rural settings presents many challenges, including patient demographics, a lack of available medical resources, a lack of multidisciplinary options, and limitations on current epidemiologic knowledge related to rurality and chronic pain. Future directions should focus on training providers to not initiate opioid medications inappropriately and to avoid abrupt cessation in patients who have been on opioids for long periods of time without careful counseling and follow up. Availability of multimodality treatment options should be developed in rural areas and additional research related to chronic pain will help elucidate prevention strategies and care solutions effective for rural communities as a vulnerable patient population.
Preventive Care for Rural Populations and Providers
Authors: Bolin Jane , Weston Cynthia , Sanaullah Syeda Fatima , Noureldin Amal A. K. , Obeidat Raghad , Page Robin
Published: November 2024

Solutions to improve preventive healthcare services in rural areas include: (1) expanding Medicaid in states that have not adopted that provision of the ACA; (2) removing physician oversight requirements for nurse practitioners in the 23 remaining states that continue to place this financial burden and restriction on nurse practitioners; (3) utilizing school-based primary care clinics; (4) educating rural residents on the importance of and need for USPSTF-recommended screenings; and (5) providing continuing education for rural providers on updates in preventive guidelines. More than ever, rural health policymakers need to be monitoring potential gaps in access to health care, as well as providing support for social determinants of health, with the goal of improving access to routine health screenings for rural residents. By increasing access to regular preventive care, we can significantly improve the health of rural communities in America.
EDMUND BLUNDEN’S WAR VERSES: NATURE AS THE UNSEEN VICTIM OF THE GREAT WAR
Authors: Alhas Hüseyin
Published: November 2024

War leaves a lasting mark not only on the lives of those directly involved but also on the natural environment profoundly, an aspect frequently overshadowed by the stark human tragedies. Edmund Blunden, a World War I poet, focuses on the environmental destruction caused by war. This article aims to analyse Blunden’s poems “Preparations for Victory” and “Thiepval Wood,” exploring the themes of desolation and the interconnected destinies of soldiers and nature through his resonant poetic expression. These poems provide a compelling lens to view an often-neglected aspect of warring: its effect on the natural world. Moving beyond traditional representations where nature is merely a setting for human struggles, Blunden portrays it as a primary victim, subjected to the harsh transformations and devastation of war. Accordingly, this study illuminates how Blunden articulates nature’s suffering and alteration fundamentally intertwined with human strife, offering a critical voice in understanding the multifaceted impacts of military conflicts.
CORROSÃO LOCALIZADA DO ALUMÍNIO EM MEIOS AERADOS E EM MEIOS COM BAIXO TEOR OXIGÊNIO: ESTUDO E COMPARAÇÃO POR MEIO DE CURVAS DE POLARIZAÇÃO
Authors: de S. Araujo João Victor , D. Gabbardo Aline , M. Fernandes Stela , Costa Isolda
Published: November 2024

LOCALIZED CORROSION OF ALUMINUM IN AERATED ENVIRONMENTS AND IN ENVIRONMENTS WITH LOW OXYGEN CONTENT: STUDY AND COMPARISON THROUGH POLARIZATION CURVES. In this study, the influence of deaeration on the electrochemical behavior of aluminum was studied by polarization techniques. The advantages of deaeration for the evaluation of localized corrosion on aluminum are discussed. The influence of the corrosive environment with low oxygen contents on the electrochemical response of aluminum was evaluated by anodic and cathodic potentiodynamic polarization curves. The polarization tests were carried out in chloride solutions followed by optical and scanning electron microscopy characterization. It was observed that deaeration of the solution significantly influences the electrochemical behavior of aluminum, as predicted by corrosion kinetics theories. For the cathodic curves, a decrease in the limiting current density for the oxygen reduction reaction (ORR) was observed for low oxygen solutions, while the “apparent” initiation of the hydrogen evolution reaction (HER) was shifted to higher potentials. In the anodic curves, a common passive behavior was not observed in aerated conditions, however, at the corrosion potential, localized pitting was observed indicating that the material was already above the breakdown potential (Ebr). In the low oxygen content solution, however, a passive region with a breakdown potential, was observed on the anodic curves.
CONTROLE DE CONVENCIONALIDADE FEITO PELO STF DIANTE DECISÕES DA CORTE INTERAMERICANA DE DIREITOS HUMANOS
Authors: Arcaro Conci Luiz Guilherme , Fioramonte Tonet Livia
Published: November 2024

O presente artigo é fruto de uma pesquisa empírica na área de direito internacional de direitos humanos e apresenta como o Supremo Tribunal Federal (STF) realiza o controle de convencionalidade diante das decisões da Corte Interamericana de Direitos Humanos (Corte IDH) em suas próprias decisões. A conclusão é de que não existe uma técnica, análise ou método para aplicação das decisões internacionais nos acórdãos, estas são usadas como as demais citações e referências ao longo do texto realizadas pelos ministros. O caminho da pesquisa perpassa por: (i) o direito internacional dos direitos humanos e o constitucionalismo multinível; (ii) o diálogo entre cortes; (iii) o controle de constitucionalidade; (iv) a Corte Interamericana de Direitos Humanos; (v) o Supremo Tribunal Federal; (vi) as análises individuais e a análise conjunta dos acórdãos extraídos da parte empírica; e (vii) a conclusão.
ENTRE ARGUMENTOS DE PRINCÍPIO E ARGUMENTOS DE POLÍTICA
Authors: De Sousa Oliveira Aldenilson , Barbosa Ramos Edith Maria , Teixeira Leal Pastora do Socorro
Published: November 2024

O crescente número de ações judiciais buscando as mais variadas prestações tem transferido ao Poder Judiciário a atribuição para decidir sobre questões importantes na área da saúde. Sob essa perspectiva, a presente pesquisa tem por objetivo explicitar e discutir a distinção estabelecida por Ronald Dworkin entre argumentos de princípio e argumentos de política. Para tanto, realiza-se, inicialmente, uma breve exposição da teoria do direito de Dworkin, com ênfase para a sua oposição à concepção positivista de Hart, notadamente à tese da discricionariedade judicial. Em um segundo momento, examina-se se a implementação do direito à saúde melhor se opera como uma questão de princípio ou de política, destacando que no caso de intervenção do Poder Judiciário deverão ser observados sempre argumentos de princípio. Trata-se de uma pesquisa qualitativa, realizada por meio de método dedutivo e de procedimento técnico de revisão de literatura e documental. Os resultados evidenciam a aplicação da distinção proposta por Dworkin nas decisões relacionadas à saúde no contexto brasileiro, apesar de reconhecer certos equívocos dos juízes na aplicação dos argumentos de princípio.
Palavras-Chave: Direito à saúde. Política pública. Princípios. Judicialização.
RESERVAS AOS TRATADOS INTERNACIONAIS DE DIREITOS HUMANOS:
Authors: Oliveira Vieira Gustavo , Sesterheim Maria Luiza
Published: November 2024

A partir da clareira aberta pela Declaração Universal dos Direitos Humanos, passou a se construir um rol de tratados internacionais em matéria de Direitos Humanos, fortalecendo e especializando a sua promoção. Em compensação, novos e mais mecanismos de implementação demandam aprimoramento no sentido de se perquirir a melhoria dos aparatos promotores da sua concretização, como é o caso da problemática que envolve o amplo uso das “reservas” aos tratados. O presente artigo enfrenta, numa abordagem dialética, um dos mecanismos ambíguos no âmbito da universalização dos Direitos Humanos, que são as reservas aos tratados internacionais sobre o assunto. O uso das reservas aos tratados internacionais, que tem limites definidos pelo próprio Direito Internacional, não permitindo ter seu funcionamento em contradição aos objetivos centrais do tratado, padece de um déficit de monitoramento e controle.  Tomando o exemplo das reservas à Convenção Internacional sobre o Direito das Crianças, problematiza-se o tema para caracterizar suas contradições e mesmo certos paradoxos, notando que nalguns casos pode funcionar (ou não).
DIREITO À SAÚDE E MEDICINA BASEADA EM EVIDÊNCIAS NA JURISPRUDÊNCIA DO ESTADO DE MATO GROSSO
Authors: Dionello Taiana Castrillon , Dezordi Wermuth Maiquel Ângelo
Published: November 2024

A medicina baseada em evidências é uma ferramenta indispensável para uma fundamentação técnica pelo julgador na adequada tutela do direito à saúde nos casos concretos. Sua relevância se torna ainda maior naqueles casos que envolvem medicamentos e/ou tratamentos de saúde ainda não aprovados pelos órgãos reguladores competentes e/ou que estão ainda em fase experimental ou de testes. Nesse sentido, o artigo realiza pesquisa e fornece um panorama atual das decisões judiciais sobre o direito à saúde e que leva em conta a medicina baseada em evidências, no cenário estadual mato-grossense. O problema que orienta a investigação pode ser sintetizado da seguinte forma: em que medida as decisões proferidas pelo Poder Judiciário do Estado do Mato Grosso, nas demandas que envolvem o direito à saúde, levam em consideração, na sua fundamentação, os critérios técnicos elaborados pela medicina baseada em evidências? Para responder à problemática suscitada, a análise voltou-se para as decisões colegiadas julgadas pelo Tribunal Regional Federal da 1ª Região, envolvendo a base territorial do Estado de Mato Grosso e o Tribunal de Justiça do Estado de Mato Grosso nos últimos 2 (dois) anos. O objetivo geral da pesquisa consiste na análise da jurisprudência dos referidos Tribunais a respeito dos casos que envolvem o direito à saúde em interface com a medicina baseada em evidências. Especificamente, o texto, que está estruturado em duas seções, busca: a) elucidar o conceito de medicina baseada em evidências e sua relevância no âmbito da efetivação do direito à saúde; b) apresentar os resultados da pesquisa jurisprudencial realizada no Estado de Mato Grosso. O método de análise empregado foi o qualitativo, na medida em que a pesquisa foi construída com base na apreciação do conteúdo de 12 (doze) acórdãos localizados, a partir dos critérios de busca já mencionados, junto ao TRF da 1ª Região e Juizado Especial Federal da 1ª Região, e de 32 (trinta e dois) acórdãos localizados junto ao repositório jurisprudencial on-line do Tribunal de Justiça do Estado de Mato Grosso. Como resultado, a pesquisa aponta que atualmente no âmbito da discussão relativa à medicina baseada em evidências, com a judicialização da saúde, o Poder Judiciário do Estado de Mato Grosso utiliza-se, na maioria dos casos, de critérios científicos para avaliar a adequação de medicamentos e procedimentos em cada caso individualizado, contudo, ainda há grande quantidade de decisões desprovidas de fundamentação que considere as melhores evidências científicas. Assim, embora já criados espaços de debate sobre o tema e núcleos de apoio técnico na Justiça mato-grossense, torna-se indispensável a intensificação de capacitação contínua de magistrados na área, para o fim de despertar a responsabilidade sobre o tema e orientar os fundamentos do direito à saúde para critérios mais técnicos e científicos.
USO INDEVIDO DE MARCAS NA PUBLICIDADE PARASITÁRIA DESENVOLVIDA NAS MÍDIAS SOCIAIS COMO CRIME DE CONCORRÊNCIA DESLEAL
Authors: Germano Alves Fabrício , Dias Souza Hellen Dayane , Da Mata Rodrigues Sousa Pedro Henrique
Published: November 2024

A publicidade parasitária, caracterizada pelo uso indevido de marcas em campanhas de marketing, tem se tornado uma prática crescente e preocupante no cenário digital atual. Esta forma de publicidade explora a reputação e o reconhecimento de marcas estabelecidas para atrair consumidores de maneira ilícita, configurando concorrência desleal. Este estudo foca especificamente no uso indevido de marcas na publicidade parasitária desenvolvida nas mídias sociais, analisando-a como um crime de concorrência desleal. Utilizando uma abordagem qualitativa, com procedimento técnico bibliográfico e documental, a pesquisa examina os impactos dessas práticas tanto para os fornecedores detentores das marcas quanto para os consumidores, que são induzidos ao erro e prejudicados em suas decisões de compra. O estudo também discute medidas jurídicas e tecnológicas para combater a publicidade parasitária, propondo soluções para garantir a proteção das marcas e promover a lealdade nas relações comerciais. Conclui-se que a efetiva aplicação de medidas preventivas e repressivas é essencial para mitigar os efeitos prejudiciais dessa prática e assegurar um mercado justo e equilibrado, dado que a concorrência desleal é tipificada como crime, principalmente a partir do art. 195 da Lei de Propriedade Industrial.
TELEMARKETING ABUSIVO:
Authors: De Negreiros Calado Vinicius , Gustavo Xavier de Albuquerque Domingos , De Paula Filho Alexandre
Published: November 2024

Quais são os mecanismos que atualmente os proprietários das linhas telefônicas podem valer-se para protegerem-se do telemarketing abusivo? A atuação do telemarketing, visando oferecer produtos e serviços por vezes se configura hostil e invasiva ao consumidor. Este trabalho foi desenvolvido em método misto, associando abordagens teórica e qualitativa e valendo-se de coleta de material bibliográfico e documental. Diante da ausência de norma proibitiva expressa na legislação federal, apresentaram-se alguns meios inibitórios, previstos notadamente por entes estaduais, a exemplo do Ato nº 10.413/2021 da ANATEL, e os meios repressivos do ordenamento jurídico, como sanções administrativas e responsabilização civil das empresas.
CHRYSANTHEMUM FLOWERS AS A SOURCE OF IDEAS FOR CREATING PARTY WEAR
Authors: Suryani Adelia , Suhartini Ratna
Published: November 2024

Chrysanthemums have several types of flowers with attractive petal shapes and colours. This research describes the making process and the result of men's and women's party wear with chrysanthemums as decorative trims. This research method uses a double-diamond design process consisting of four stages: discovered, defined, developed, and delivered. The discovery stage is the stage of finding the source of ideas as outlined in the mood board, inspired by the arrangement of petals and varied colours in flowers. The defined stage was to create eight designs of women's party wear and four designs of men's party wear based on the mood board. In the development stage, the women's party fashion will be created using the draping technique on a medium-sized mannequin, and the men's party wear will be created using a large-size construction pattern. The deliver stage is the stage of making decorative trims in the form of chrysanthemum flowers and fabric manipulation tucking as the centre of attention on the apparel. The result of the research was a party dress that was based on the source of the chrysanthemum flower idea. Recommendations for future research can explore the application of chrysanthemum flower idea sources on different designs.