bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparison of the efficacy of interlesional corticosteroid and silicone gel for keloid treatment: a review article
Authors: Limanda Claudia Felicia , Widhiartini Ida Ayu Alit
Published: May 2023

Keloid is an abnormal scar associated with various skin problems including physical and psychological distress. Keloid is often presented as skin itching, swelling, and pain with possible complications such as recurrent sequelae and stigma. Prevention and treatment of this problem include topical non-invasive and invasive options, such as silicon-based products and corticosteroids which are available in the market. Silicon is stated as a standard product, however, is used more often as a combination with corticosteroids than single use. Effectiveness of both products have been discussed separately in previous studies, making it unclear which one is more superior. Thus, a review is needed to ensure their uses in daily practice and to determine their superiority as a single or combination treatment in order to apply them efficiently. Aim of this study is to compare effectiveness of corticosteroids and silicone products to prevent or treat keloid. Keywords such as "keloid," "corticosteroid," and "silicone products" were used in PubMed, national library of medicine, ResearchGate, and dermatology textbooks. Journals found were analyzed for their validity and reliability before the compilation of this review article. Results found stated that both silicone pharmaceutical products and corticosteroids have their own benefits and risks. In addition, according to their treatment phase, they can be used as single or combination treatment. However, due to limited existing studies found, further research is necessary.
A review on determinants and barriers affecting the transition from curative care to palliative care in patients suffering from terminal cancer
Authors: Sharma Karan , Prathipati Roja Prasanthi , Agrawal Aniket , Shah Kavita
Published: May 2023

The integration of palliative care into comprehensive cancer care has become increasingly recognized as an essential aspect of cancer treatment. Palliative care can improve patient outcomes, symptom management, and overall satisfaction with care. However, despite the benefits of palliative care, several barriers exist that prevent its widespread implementation, including lack of awareness and understanding of palliative care, lack of access to palliative care services, and stigma associated with palliative care. The decision to transition from curative to palliative care is complex and influenced by several factors, including patient preferences, disease stage, and prognosis, symptom burden, comorbidities, and social support. Effective communication between healthcare providers, patients, and families is essential in ensuring that patients are informed about their options and can make informed decisions about their care. This literature review aims to explore the factors that influence the decision to transition to palliative care and to identify the barriers to the implementation of palliative care in cancer patients. The review also discusses strategies to overcome these barriers and highlights the importance of integrating palliative care into cancer care from the time of cancer diagnosis.
Multiple core histopathologies for discriminative diagnosis of phyllodes pathology in breast
Authors: Singh Vijay Pratap , Singh Akash Kumar , Jha Arun Kumar , Sircar Sumantra , Singh Vishal Mohan , Verma Pranab Kumar , Jaipuriyar Manish , Ranjan Priyadarshi , Singh Chandan Kumar , Kumar Sanjay
Published: May 2023

Background: Historical patient’s records were analyzed. Patients diagnosed with phyllodes tumors of the breast who   received preoperative core needle biopsy and undergone breast surgery at a tertiary cancer centre in Patna, Bihar, India from January 2020 to December 2020. The resulting data allowed us to compare the accordance between core needle biopsy and final histopathology of phyllodes tumor    of the breast patients and evaluate the accuracy of core needle biopsy in preoperative diagnosis.
Methods: This is a retrospective study evaluated the case records of one hundred twenty (n=120) patients for core needle biopsy findings and subsequent histopathology reports post-surgery. Sensitivity and significance of core needle biopsy was determined for phyllodes tumor of the breast.
Results: A total of one hundred twenty (n=120) patients’ data were analyzed. There were ninety (n=90) fibroadenoma and thirty (n=30) phyllodes tumor patients. Sensitivity of core needle biopsy for benign tumor was 64.2%, borderline 40% and a malignant phyllodes tumor was 100% respectively.
Conclusions: Core needle biopsy provides a pathological basis for pre-operative diagnosis of phyllodes tumor, but it has a low accuracy and offers limited guidance for surgical decisions, if used alone. An integrated assessment using needle biopsies in combination with clinical data and imaging features is suggested as a reliable strategy to aid phyllodes tumor diagnosis and subsequent treatment.
Duplex collecting system with renal malrotation: an unusual combination
Authors: Secodiningrat Raden H. P. S. , Singgih Nicholas A. , Oktaviani Jacinda R. , Manuputty Egi E.
Published: May 2023

Both duplex collecting system and renal malrotation are congenital developmental anomalies of kidney. They usually present asymptomatic and accidentally diagnosed while patients undergo radiology examinations. We are reporting a case of a 33-year-old-male with a combination of duplex and malrotation kidney. Although these two are common anomalies of kidney, their combination is extremely rare. We found only two reports that had similar combined cases, so our case is the third reported.
Ileo-ileal knotting masquerading as internal hernia: a rare cause of acute intestinal obstruction
Authors: Kumar Manish , Khanna Rahul , Meena Ram N. , Mishra Shashi P. , Panigrahy Panchanana , Anand Akshay , Kumar Binod
Published: May 2023

Intestinal knotting is a rare cause of acute intestinal obstruction and in most cases is diagnosed intraoperatively due to its rarity and uncommon presentation. Out of different types of intestinal knots, ileo-ileal knotting is rarest and very few such cases have been reported in the literature. Due to very high mortality, early diagnosis and immediate surgical intervention are needed. Here we present a case of a 52-year-old male patient who presented with a history of non-passage of stool and flatus, after resuscitation patient was planned for exploratory laparotomy. Findings revealed gangrenous ileal loops and an ileo-ileal knot masquerading as an internal hernia. End-to-end anastomosis of the gangrenous ileum was done along with a decompressive proximal loop ileostomy. The patient was transferred to the intensive care unit after surgery. He died on postoperative day 1 due to metabolic acidosis with endotoxic shock. By reporting this case we want to emphasize on the need of keeping intestinal knots as a differential diagnosis while operating a case of acute intestinal obstruction.
Extra cardiac perforation following failed percutaneous transvenous mitral commissurotomy
Authors: T. R. Sunil Kumar , Karthik Kumar  , Mahesh Kumar Aishwarya
Published: May 2023

Percutaneous transvenous mitral commissurotomy (PTMC) is the procedure of choice for select patients with mitral valve disease who have favorable valve architecture and meet the requirements for balloon valve dilatation. Complications following PTMC are rare (<3%). A 56-year-old woman with rheumatic valvular heart disease, severe mitral stenosis and moderate mitral regurgitation in atrial fibrillation underwent elective PTMC. She developed an extra-cardiac perforation during PTMC because of abnormal catheter course, and underwent emergency mitral valve replacement with extra-cardiac perforation repair. Catheter-related complications following PTMC are rare but not unheard of. Prompt management of immediate complications result in favorable outcomes.
A rare case of wandering spleen with its unreported associations: case report and literature review
Authors: Digumarthi Asha R. , Khanna Seema , Satendra Kumar  , Sanjeev K. Gupta
Published: May 2023

Wandering spleen (WS) is a rare clinical entity with unclear clinical picture. Patient can be asymptomatic or can present with acute abdomen, based on the degree of associated splenic torsion, but most of the cases needed an emergency splenectomy. We herein report an unusual presentation of a wandering spleen in the elderly with thrombocytosis, portal, and splenic vein thrombosis, and sinistral hypertension. To the best of our knowledge, this is the first case report documenting all these associations altogether. This case report describes how this challenging case was managed well. Splenectomy was inevitable in this patient as the spleen was infarcted. This enlightens the need for timely diagnosis and intervention of wandering spleen for splenic preservation.
Peritoneal dermoid cyst, rare location with no other primary focus: a rare case report
Authors: Sai Sampath Kumar Vasantham  , Jameel Akhter
Published: May 2023

Growth of dermoid cyst on parietal peritoneum without any prior history of ovarian dermoid cyst is considered a rare condition. The presentation of peritoneal dermoid cyst is vague and depends on the location of the cyst. We report a case of a 28-year-old young female who presented at our outpatient department with vague right upper quadrant pain and no other complaints, but upon examination a swelling was felt on the right upper quadrant, she was investigated radiologically, which reported as a peritoneal cyst, she was taken up for surgery. The cyst was excised and confirmed histopathologically as a dermoid cyst. Clinical progress was uneventful and postoperative recovery was excellent.
Iatrogenic bile duct injury: a stitch in time
Authors: Mangipudi Surya Pratap  , Ravi Ranjan  , Gyan Saurabh  , Ranvir Singh
Published: May 2023

Intraoperative bile duct injuries often are difficult to be identified intraoperatively can lead to a variety of complications and require complex surgical procedures for their definitive treatment. With multiple complicated treatment options, these injuries become a therapeutic challenge. We present a case of a 49-year-old lady diagnosed with symptomatic gallstone disease who underwent open cholecystectomy in an outside hospital, during which she had an iatrogenic bile duct injury which was diagnosed postoperatively. She was promptly referred to a higher centre. After investigations, the patient underwent a Roux-en-Y hepaticojejunostomy with a subhepatic drain. The patient was discharged post-successful recovery on post-op day 7.  Iatrogenic bile duct injury can be missed intraoperatively in a cholecystectomy. The patient provides non-specific symptoms, and a high degree of suspicion can help in early diagnosis. Prompt treatment by an experienced hepatobiliary surgeon is necessary for the successful treatment of the condition.
Patella thickness in TKR- Intra operative measurement in Indian population
Authors: Kedia Ankit , Kadian Anuj Kumar
Published: May 2023

Patellar resurfacing is one of the most contentious issues in total knee replacement, with anterior knee pain ranging from 4 to 49% post TKR. One of the important decision maker in patellar resurfacing techniques is thickness of patella. Minimum 14 mm native patella thickness is essential after 8 mm cut, to avoid patellar complications like loosening, pain and crepitus.

We present a study of patellar sizes in Indian population, taken intra-operatively while performing total knee replacement of 73 consecutive knees. We measured thickness, superoinferior and mediolateral dimensions and compared them with height, weight and implant size.

The average patellar size in Indian adults was 21.7 mm with 42 knees having patellar size less than 22 mm. In males it was 24.3 mm and in Indian adult females it was 20.8 mm. The patellar size had significant direct correlation with height of the patient. And smaller femoral and tibial implant size correlated with smaller patellar thickness.

Average patellar thickness in Indian adults is small. Patelloplasty is a better alternative for such patients than resurfacing.
A case of proximal femoral giant cell tumor treated with total hip arthroplasty following a pathological fracture
Authors: Paigude Prithviraj Anil , Bartakke Girish , Lakde Shubham , Puranik Rahul , Katkar Minish
Published: May 2023

Giant cell tumors occurring in the proximal femoral region are rather rare and present as challenges to physicians due to their aggressive nature leading to pathological fractures. Preservation of the hip joint is rather difficult due to their affinity to the periarticular area. As per vast literature search, reconstruction of the proximal femoral region using total hip arthroplasty provide favorable results compared to hip preservation in terms of functional outcomes and reduced recurrence rates. Hereby, we present our experience in a case of proximal femoral giant cell tumor managed with total hip arthroplasty following pathological fracture.
Impact of COVID-19 containment measures on children with cancer in Indonesia
Authors: El Salih Ibrahim , Widjajanto Pudjo Hagung , Sutrisni Sri , Hoogland Iris , Kaspers Gertjan , Mostert Saskia
Published: May 2023

Containment measures to limit COVID-19 spreading profoundly impact children around the globe, especially in low- and middle-income countries such as Indonesia. The aim of this case series study is to uncover the impact that COVID-19 measures have on Indonesian children with cancer and their families.

A case series study was conducted in July 2021. Investigators identiﬁed three children diagnosed with cancer at an Indonesian referral hospital and studied their medical records. Caretakers were interviewed inside the hospital by an independent interviewer using a semi-structured questionnaire.

This study presents three children with cancer and their families. Access to proper healthcare was hindered during COVID-19 pandemic due to mobility restrictions, medical staff shortage, limited chemotherapy and blood products availability, postponed medical procedures, and delayed or modified treatment administration. Financial hardships resulted because caretakers lost their jobs due to lockdowns and medication costs were no longer fully covered by health-insurance. Children and their relatives suffered from mental health issues. Anxiety, depression, stress and loneliness were caused by the fear of receiving suboptimal cancer treatment, serious concerns about financial difficulties, and restricted social interactions. All families believed that COVID-19 measures worsened their children’s survival chances.

COVID-19 measures adversely impact children with cancer and their families in Indonesia, and most likely in other low- and middle-income countries as well. Disruptions in timely and adequate childhood cancer treatment administration may importantly deteriorate survival chances. Governments and policymakers should take these indirect effects into account to protect vulnerable children and their families.
Preliminary proteomic analysis of human tears in lacrimal adenoid cystic carcinoma and pleomorphic adenoma
Authors: Yue Han ,   Department of Ophthalmology, Eye & ENT Hospital of Fudan University, Shanghai 200031, China; Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai 200031, China, Zhang Rui , Qian Jiang ,   Department of Ophthalmology, Eye & ENT Hospital of Fudan University, Shanghai 200031, China; Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai 200031, China,   Department of Ophthalmology, Eye & ENT Hospital of Fudan University, Shanghai 200031, China; Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai 200031, China
Published: May 2023

AIM: To detect proteomic differences in tears between adenoid cystic carcinoma (ACC) and pleomorphic adenoma (PA).
METHODS: Tear samples were collected from 4 patients with ACC, 5 with PA, and 4 control cases. Label-free analysis and parallel reaction monitoring (PRM) were used to screen and validate the tear proteome. Gene Ontology (GO) annotation and Kyoto Encyclopedia of Genes and Genomes (KEGG) were conducted for bioinformatics analysis.
RESULTS: In total, 1059 proteins in tear samples were identified by label-free analysis. Between ACC and PA, 415 differentially expressed proteins were detected. Based on the GO annotation, enzyme regulator activity and serine-type endopeptidase inhibitor activity in the molecular function category, blood microparticle and extracellular matrix in the cellular component category, and response to nutrient levels in the biological process category were most predominant. By KEGG pathway annotation, the different proteins between ACC and PA mainly participated in complement and coagulation cascades, amoebiasis, African trypanosomiasis and cholesterol metabolism. Eight proteins with mostly significant differences were verified by PRM, and five proteins with more than 10-fold increases in ACC compared with PA, including integrin β, α-2-macroglobulin, epididymal secretory sperm binding protein Li 78p, RAB5C, and complement C5, were identified.
CONCLUSION: The combined tools of label-free analysis and PRM are very effective and efficient, especially for samples such as tears. Some proteomic differences in tears between ACC and PA are identified and these protein candidates may be specific biomarkers for future exploration.
Different serum levels of IgG and complements and recurrence rates in IgG4-positive and negative lacrimal gland benign lymphoepithelial lesion
Authors: Liu Rui ,   Beijing Ophthalmology and Visual Sciences Key Laboratory, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China, Wang Jin-Jin , Li Jing , Ge Xin , Zhang Jing-Xue , Ma Jian-Min ,   Beijing Ophthalmology and Visual Sciences Key Laboratory, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China,   Beijing Ophthalmology and Visual Sciences Key Laboratory, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China,   Beijing Ophthalmology and Visual Sciences Key Laboratory, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China,   Beijing Ophthalmology and Visual Sciences Key Laboratory, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China,   Beijing Ophthalmology and Visual Sciences Key Laboratory, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China
Published: May 2023

AIM: To analyze the differences in immune indicators and prognosis between IgG4-positive and negative lacrimal gland benign lymphoepithelial lesion (LGBLEL).
METHODS: This was a single-center retrospective clinical study including 105 cases of IgG4-positive LGBLEL and 41 cases of IgG4-negative LGBLEL. Basic information, related indicators of peripheral venous blood samples using immunoscattering turbidimetry, treatment (partial surgical excision and glucocorticoid therapy) and prognosis (recurrence and death) were collected. Survival curves for recurrence were created using the Kaplan-Meier analysis. Univariate analysis and multivariate regression analysis were used to analyze prognostic factors.
RESULTS: The mean age was 50.10±14.23y and 44.76±11.43y (P=0.033) in IgG4-positive and negative group respectively. The serum C3 and C4 was lower in IgG4-positive group (P=0.005, P=0.002), while the serum IgG and IgG2 was higher in IgG4-positive group (P=0.000 and P=0.008). Twenty-one cases had recurrence in IgG4-positive group and 3 cases recurrence in IgG4-negative group. The 5-year recurrence-free cumulative percentages of IgG4-positive group was 81.85%, and 83.46% in the IgG-negative group (P=0.216). The history of preoperative glucocorticoid therapy, serum C4, IgG1 and IgG2 were the factors affecting recurrence in IgG4-positive group, while serum C4, and IgG1 were the factors affecting recurrence of LGBLEL.
CONCLUSION: Serum C4 and IgG1 are the factors affecting recurrence of LGBLEL, while the IgG4 does not affect recurrence of LGBLEL.
Time in range as a useful marker for evaluating retinal functional changes in diabetic retinopathy patients
Authors: Zhu Dan-Dan ,   Department of Ophthalmology, Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School, Nanjing 210000, Jiangsu Province, China, Cheng Xin-Xuan , Ding Ning ,   Department of Ophthalmology, Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School, Nanjing 210000, Jiangsu Province, China,   Department of Nutrition and Food Hygiene, Nanjing University of Chinese Medicine, Nanjing 210000, Jiangsu Province, China
Published: May 2023

AIM: To elucidate the relationship between macular sensitivity and time in range (TIR) obtained from continuous glucose monitoring (CGM) measures in diabetic patients with or without diabetic retinopathy (DR).
METHODS: This was a cross-sectional study including 100 eyes of non-DR patients and 60 eyes of DR patients. An advanced microperimetry was used to quantitate the retinal mean sensitivity (MS) and fixation stability in central macular. TIR of 3.9-10.0 mmol/L was evaluated with CGM. Pearson coefficient analysis and multiple linear regression analysis were used to assess the correlation between TIR and retinal sensitivity.
RESULTS: In a comparison of non-DR patients, significant differences (P<0.05) were found in HbA1c, TIR, coefficient of variation (CV), standard deviation of blood glucose (SDBG) and mean amplitude of glucose excursion (MAGE) values in DR patients. Besides, those DR patients had significantly poor best-corrected visual acuity (BCVA, logMAR, P=0.001). In terms of microperimetry parameters, retinal mean sensitivity (MS) and the percentages of fixation points located within 2° and 4° diameter circles were significantly decreased in the DR group (P<0.001, P<0.001, P=0.02, respectively). The bivariate contour ellipse area (BCEA) encompassing 68.2%, 95.4%, 99.6% of fixation points were all significantly increased in the DR group (P=0.01, P=0.006, P=0.01, respectively). Correlation analysis showed that MS were significantly correlated with HbA1c (P=0.01). TIR was positively correlated with MS (r=0.23, P=0.01). SDBG was negatively correlated with MS (r=-0.24, P=0.01) but there was no correlation between CV and MAGE with MS (P>0.05). A multivariable linear regression analysis was performed to prove that TIR and SDBG were both independent risk factors for MS reduction in the DR group.
CONCLUSION: TIR is correlated with retinal MS reduction in DR patients, suggesting a useful option for evaluating DR progression.
Estudo qualitativo da água no município de Picuí-PB, enfocando os parâmetros cor, turbidez e pH
Authors: Gomes Adely Suelma Pereira , Silva Carisa Rocha da , Moreira Aldenice Amélia Dantas , Araújo Ilka Nayara da Silva , Pereira Frederico Campos
Published: May 2023

A disponibilidade de água com qualidade é indispensável para a manutenção da vida, todavia, a qualidade deste recurso tem sido alterada de forma continuada devido ao manejo inadequado e a intervenção antrópica nos agroecossistemas. Devido a essa realidade a disputa por este recurso tem gerado grandes conflitos em função da alteração da sua qualidade como também de sua iminente escassez. Este trabalho tem por objetivo avaliar a qualidade de água para consumo humano, no município de Picuí-PB, classificando os padrões de cor, turbidez e pH, com enfoque no rio Picuí (afluente principal), açude Várzea Grande (principal fonte de distribuição), açude Picuí (fonte secundária de distribuição) e uma torneira aleatória. As amostras de água foram coletadas e analisadas laboratorialmente, entre os meses de janeiro e março de 2012. Observou-se uma disparidade nos índices do rio Picuí, açude Várzea Grande e açude Picuí, tornando imprópria para o consumo humano, necessitando assim, um monitoramento sustentável dos corpos hídricos; com relação à água da torneira esta se apresenta em conformidade com os parâmetros de pH e turbidez.
Desarrollo y validación de una escala de ansiedad basada en el modelo de los Cinco Factores
Authors: Abal Facundo Juan Pablo , Lozzia Gabriela Susana , Attorresi Horacio Félix
Published: May 2023

Se presenta el proceso de construcción de una escala para medir la faceta Ansiedad según el Modelo de los Cinco Factores. A partir de una revisión de las definiciones teóricas y operacionales de autores relevantes en el tema, se redactaron 13 ítems con formato tipo Likert. Estos ítems fueron sometidos a juicio experto y una prueba piloto. Luego se administraron a 742 adultos de población general residentes en el área metropolitana de Buenos Aires, Argentina (55.3% mujeres, edad media = 38 años y DE = 13.9 años). Se verificó la unidimensionalidad mediante un análisis factorial exploratorio. El ajuste del Modelo de Respuesta Graduada de Samejima (2010) fue satisfactorio para todos los ítems. Se aportan evidencias de validez convergente y discriminante con Big Five Inventory y SCL-90-R. No se halló funcionamiento diferencial del ítem por género. Se obtuvieron indicadores óptimos de consistencia interna (Alfa de Cronbach = .85, Alfa Ordinal = .88 y Omega Ordinal = .88). La fiabilidad marginal obtenida en el marco de la Teoría de Respuesta al Ítem resultó de .88. La Función de Información del Test fue adecuada en un rango amplio de niveles del rasgo latente. Se concluye que la escala de la faceta Ansiedad cuenta con evidencias de validez y confiabilidad suficientes que dan garantías para su aplicación.
Enemy at the gates. Analysis of media discourse on the wPolityce.pl portal (August 18 – September 6, 2021) regarding the refugee camp in Usnarz
Authors: Wezgraj Jacek
Published: May 2023

Celem artykułu była analiza dyskursu medialnego w portalu wPolityce.pl, związanego z kryzysem uchodźczym na granicy polsko-białoruskiej (lato − jesień 2021). Zastosowano indukcyjną analizę tematyczną zebranego materiału, wyodrębniając osiem zasadniczych wątków tematycznych, a następnie przestudiowano wypowiedzi pojawiające się w mediach. W jej toku wysunięto wniosek, że sytuacja w pobliżu polsko-białoruskiej granicy to przejaw wojny hybrydowej przeciwko Polsce. Po stronie atakujących znajduje się nie tylko reżim Aleksandra Łukaszenki, lecz również osoby, partie polityczne oraz organizacje mające krytyczne nastawienie do rządów Zjednoczonej Prawicy. W celach politycznych, ze względu na niechęć do rządzących, wpisują się w „scenariusz” przygotowany przez białoruskiego dyktatora i bezpośrednio lub pośrednio szkodzą w ten sposób polskiemu państwu. Dokonano również próby interpretacji postaw obiorców oraz emocji, jakie mogą wywoływać w nich tego typu teksty. Zastosowana retoryka może z jednej strony budzić niechęć i złość wobec partii mających mniejszość w parlamencie, z drugiej zaś przekonanie o bezwzględnej słuszności postępowania rządu i wspierających go osób, instytucji, środowisk. W odniesieniu do osób koczujących na granicy u odbiorców portalu pojawiać się mogą: strach, poczucie zagrożenia oraz przekonanie, że władze Białorusi chcą narzucić Polakom coś nieakceptowalnego, sprowadzając na nich tym samym zagrożenie. U czytelników portalu może pojawić się również brak zaufania i niechęć do mediów niesprzyjających rządowi, przedstawianych jako niewiarygodne czy podające fałszywe lub niesprawdzone informacje. Z kolei rząd oraz partie wchodzące w skład Zjednoczonej Prawicy są prezentowane jako stojące na straży polskiego interesu i bezpieczeństwa państwa. Zidentyfikowano w związku z tym elementy dyskursu nacjonalistycznego.
Correlation of Tooth Shade with Age and Gender: Promising Applications in Aesthetic and Forensic Dentistry
Authors: Goyal Shree , Chaudhary Rishabh , Juneja Saurabh , Charan Shetty Devi
Published: May 2023

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Navigating the Ethical Challenges of Artificial Intelligence in Higher Education: An Analysis of Seven Global AI Ethics Policies
Authors: Slimi Zouhaier , Villarejo Carballido Beatriz
Published: May 2023

AI use in higher education raises ethical concerns that must be addressed. Biased algorithms pose a significant threat, especially if used in admission or grading processes, as they could have devastating effects on students. Another issue is the displacement of human educators by AI systems, and there are concerns about transparency and accountability as AI becomes more integrated into decision-making processes. This paper examined three AI objectives related higher education: biased algorithms, AI and decision-making, and human displacement. Discourse analysis of seven AI ethics policies was conducted, including those from UNESCO, China, the European Commission, Google, MIT, Sanford HAI, and Carnegie Mellon. The findings indicate that stakeholders must work together to address these challenges and ensure responsible AI deployment in higher education while maximizing its benefits. Fair use and protecting individuals, especially those with vulnerable characteristics, are crucial. Gender bias must be avoided in algorithm development, learning data sets, and AI decision-making. Data collection, labeling, and algorithm documentation must be of the highest quality to ensure traceability and openness. Universities must study the ethical, social, and policy implications of AI to ensure responsible development and deployment. The AI ethics policies stress responsible AI development and deployment, with a focus on transparency and accountability. Making AI systems more transparent and answerable may reduce the adverse effects of displacement. In conclusion, AI must be considered ethically in higher education, and stakeholders must ensure that AI is used responsibly, fairly, and in a way that maximizes its benefits while minimizing its risks.
Monitoring of the Fe2O3 Particle Size Distribution by Intensity in the Context of Digital Company
Authors: Marticek Matus , Knapcikova Lucia , Tauberova Rebeka
Published: May 2023

This research studies monitoring of Fe2O3 iron particle size produced in industrial companies on the premises of a hot rolling mill. The analysis used the distribution curve method - particle size distribution by intensity. This method determined which particles occur most often in the sample, what is the average particle size, smallest and largest particles. Digitization of individual procedures and monitoring of technological processes provides data that can be worked with at a given time.The obtained data represent a source of information for their further processing in the field of maintenance prediction.
Mobile Applications in Childhood Immunization: A Systematic Review
Authors: Mejia Cristian Tinoco , Necochea-Chamorro Jorge Isaac
Published: May 2023

The central objective of this paper is to distinguish the impact of different cell phone applications on child vaccination completion. A systematic literature review was conducted to determine how mobile applications have improved the acceptance, education, and fulfillment of vaccines. To this end, an analysis of the aspects, objectives, and differentiated technologies that have fostered the growth of mobile applications and new technologies in childhood immunization is presented. In addition, the obstacles to achieving positive results reported in the scientific literature are identified. Lastly, suggestions are made for future work to improve childhood immunization coverage.
The Proposal of Data Sharing Platform Principles for Academic Spin-off Companies
Authors: Boubin Jan
Published: May 2023

In order to streamline the technology transfer process, eliminate errors and speed up the implementation of new innovations, the author proposes basic principles for creating a platform for sharing information between spin-off companies, which will enable effective cooperation between individual entities with the potential to have a positive impact on the economic and technological environment. By studying research on the topic of strategy, innovation and data sharing, the author compiled the basic principles of the platform according to the qualitative Grounded theory method with regard to the practical usability of the created proposal.
Extracting Patterns of Proximity in Regional Development Inequality Using Hierarchical Agglomerative Clustering
Authors: Munandar Tb Ai , Handayani Dwipa
Published: May 2023

Equitable regional development is still difficult to implement. Many interests in determining regional development priorities make it difficult to realize the main goals of national development. Political interests and the underutilization of regional statistical data are often other obstacles in carrying out regional development. This study aims to classify regional development data to be used to analyse existing development inequalities. Gross regional domestic income (GRDP) data is the main data in this study. The researcher used the hierarchical agglomerative clustering (HAC) technique. The results of the cluster can be used as a consideration for local governments to determine future regional development priorities. In addition, visualized cluster results in the form of a dendrogram can show the proximity of development inequality between regions.
Model of Watershed Segmentation in Deep Learning Method to Improve Identification of Cervical Cancer at Overlay Cells
Authors: Riana Dwiza , Jamil Muh , Hadianti Sri , Na’am Jufriadif , Sutanto Hadi , Sukwadi Ronald
Published: May 2023

Cervical cancer is a disease that is very scary for women because it is the cause of death among women. To be aware of this disease is to do an early examination through the Pap Smear (PS) test. In terms identifying overlapping cancer cells, it still has low accuracy. Therefore, this research was carried out with the aim of getting the level of cell separation with high accuracy. This study uses a model to develop the Watershed segmentation technique in the Deep Learning Method. The data tested in this study comes from the RepomedUNM dataset. The amount of data tested is 420 overlapping images with the formulation of 1,260 test images. The results of this study can very well separate each overlapping cell with an average Intersection over Union (IoU) score of 0.9061. Each result can be divided fully by the whole of its area, so the final results of overlapping cells were successfully separated with an average score of 0.945. Therefore, this research can be used as a reference in identifying cervical cancer cells.
Evaluation of Different Types of Communication Used in Aircraft Maintenance
Authors: Sekelová Ingrid , Korba Peter , Al-Rabeei Samer
Published: May 2023

Aircraft maintenance is an essential part of aviation that ensures the safety of the aircraft, which is achieved by effective communication. Since English is the language of aviation, it is also present in aircraft manuals and other necessary documentation for aircraft maintenance. The data was gathered by means of a questionnaire at the MRO facility in Eastern Slovakia and was processed by the statistical software Jamovi. This research besides other findings revealed that the most common types of communication are; reading the written text and engaging in dialog. This article revealed the importance of continuous training in the English language.
Universalização do ensino médio com qualidade social: desafios dos estados de Alagoas e Goiás
Authors: Costa Gilvan Luiz Machado , Silva Mônica de Morais Sampaio
Published: May 2023

O artigo buscou responder à pergunta diretriz: quais os limites e possibilidades à universalização do Ensino Médio com qualidade social nos estados de Alagoas e Goiás? No âmbito dos aspectos teórico-metodológicos, optou-se pela abordagem dialética. Foram utilizados dados estatísticos relacionados, obtidos por meio da Pesquisa Nacional por Amostra de Domicílios Contínua e do Censo Escolar, nos anos de 2016 e 2019. O estudo aponta as desigualdades educacionais entre dois estados de uma mesma nação e a distância que ambos estão da materialização do proposto nas metas do Plano Nacional de Educação (2014-2024). Ao Ensino Médio é relevante e urgente ter todos os jovens de 15 a 17 regularmente matriculados, professores com formação e condições de trabalho adequadas e, por fim, mas não menos importantes, escolas com infraestrutura ampla. Materializar as metas estabelecidas no Plano Nacional de Educação é um caminho profícuo à universalização do Ensino Médio com qualidade social.
A Novel Method Development and Validation by Ultra-Performance Liquid Chromatography for Assay of Asciminib in Dosage Form
Authors: GADDEY Pridhvi Krishna , SUNDARARAJAN Raja
Published: May 2023

The main objective of the present study was to develop and validate simple, precise, sensitive and accurate UPLC method for the estimation of asciminib in pure and dosage form. The UPLC method was developed by using Waters Acquity liquid chromatographic system and Zorbax Phenyl (100x1.0mm,1.7µm) column. The developed method was validated according to the international conference on harmonization (ICH) guidelines. The chromatographic separation of asciminib with good resolutions has been achieved by using the mobile phase acetonitrile: ammonium dihydrogen phosphate buffer (20:80 v/v) at a flow rate of 0.5 mL/min, injection volume of 5 µL, and at 242 nm wavelength. The validated method was found to be linear in the range of 4 - 60 µg/mL. The limit of detection (LOD) and limit of quantification (LOQ) for asciminib were found to be 0.4 and 0.12 µg/mL respectively. The % RSD was found to be less than 2 % revealing the precision of the developed method. Besides, the recovery rate was observed close to 100 % confirming the accuracy of the method. Minor alterations in the chromatographic conditions have revealed robustness and ruggedness of the developed method. The developed analytical method is simple, precise, sensitive, and reproducible which can be used for the estimation of asciminib.
Acil servise başvuran yaşlı hastalarda eritorist dağılım genişliği ile hastane içi mortalitesi arasındaki ilişki
Authors: ŞAHİN Yusuf , AKYOL Pınar Yeşim , KARAKAYA Zeynep , TOPAL Fatih , ÇAKIR Adem
Published: May 2023

Amaç: Eritrosit dağılım genişliği tam kan sayımı incelemesinde kullanılan bir parametredir. Son çalışmalar, kırmızı kan hücresi dağılımının, birçok hastalıkta mortalitede klinik olarak anlamlı prediktif değerde artan mortalite ile ilişkili olduğunu göstermektedir. Hastaneden taburcu olan hastaların eritrosit dağılım değerleri ile hastaneye yatan hastaların RDW düzeylerini karşılaştırdık ve hastane içi mortalite ile ilişkisi olup olmadığını araştırdık.

Gereç ve Yöntemler: Bu çalışma acil serviste yapılmış kesitsel retrospektif bir çalışmadır. Dışlama kriterlerini karşılamayan toplam 843 kişi (435 çalışma(eski) grubu ve 408 kontrol grubu) çalışmaya dahil edildi. Eritrosit dağılım değerleri çalışma ve kontrol gruplarına göre değerlendirildi.

Sonuç: Çalışma(eski) grubunda kırmızı kan hücresi dağılımının ortalama değeri 16.03 olarak bulundu. Kontrol grubunda ortalama eritrosit dağılımı değeri 14,67 bulundu. Mann Whitney U testi ile karşılaştırıldığında çalışma(eski) grubunda kırmızı kan hücre dağılım değerinin kontrol grubuna göre anlamlı olarak arttığı ve mortalite ile ilişkili olduğu gösterildi (p
Kendine Zarar Verme Davranışı Olan Ergenlerde Aile İşlevlerinin, Ebeveyn Ve Arkadaşlara Bağlanmanın, Karar Verme Stillerinin Ve Problem Çözme Becerilerinin Değerlendirilmesi
Authors: KAVURMA Canem , BİLAÇ Öznur , ÖNDER Arif , DOĞAN Yakup , UZUNOĞLU Gülçin , ADANİR Asli , KANDEMİR Hasan
Published: May 2023

AMAÇ: Kendine zarar verme davranışı, intihar amacı olmaksızın kişinin kendi bedenine yönelik zarar verici davranışta bulunmasıdır. Yapılan çalışmalarda birçok psikiyatrik bozuklukla beraber olabildiği gösterilmiştir. Ayrıca kendine zarar verme davranışının etiyolojisinde kişiler arası etkileşim (aile ve arkadaşlara bağlanma), akran zorbalığı, istismar öyküsü gibi birçok etkenin yer aldığı bilinmektedir. Kendine zarar verme davranışı olan ergenlerin klinik uygulamalarda problem çözme ve karar verme becerilerinde güçlükler yaşadıkları görülmekle birlikte bu alanda yazında oldukça az araştırma olduğu dikkati çekmektedir. Çalışmamızda kendine zarar verme davranışı nedeniyle polikliniğe başvuran ergenlerin karar verme stillerini, problem çözme becerilerini, arkadaş ve ebeveyne bağlanmalarını, aile özellikleri ve işlevselliklerini sağlıklı ergenlerle karşılaştırarak incelemeyi amaçladık.

GEREÇ ve YÖNTEMLER: Çalışmamıza Manisa Ruh Sağlığı ve Hastalıkları Hastanesine başvuran, kendine zarar verme davranışı olan, 10-17 yaş aralığında bulunan 46 olgu ve 33 sağlıklı kontrol alınmıştır. Olgu ve kontrol grubundaki her ergene sosyodemografik veri formu, aile değerlendirme ölçeği, ebeveyn ve arkadaşlara bağlanma envanteri, ergenlerde karar verme ölçeği ve problem çözme envanteri uygulanmıştır.

BULGULAR: Gruplar sosyodemografik veriler açısından karşılaştırıldığında olgu grubunda anne baba boşanmasının daha sık ve ailenin aylık gelirinin daha düşük olduğu sonucuna varılmıştır. Kendine zarar veren grupta sigara kullanımı ve intihar girişimi istatistiksel olarak anlamlı derecede yüksek bulunmuştur. Kendine zarar veren ergenlerde aile değerlendirme ölçeğinin gereken ilgiyi gösterme ve genel işlevler alt boyutunda kontrol grubuna göre anlamlı derecede olumsuzluk saptanmıştır. Ergenlerde karar verme ölçeği değerlendirildiğinde karar vermede öz saygı bölümü kendine zarar veren grupta anlamlı derecede düşük bulunmuştur. Aynı ölçeğin panik kısmı hasta grubunda anlamlı derecede yüksek bulunmuştur. Kendine zarar veren grupta bağlanma envanterinin ebeveyn alt ölçeği anlamlı derecede düşük bulunmuştur. Problem çözme envanteri değerlendirildiğinde kendine zarar veren grupta anlamlı derecede yüksek puan aldığı saptanmıştır.

SONUÇLAR: Kendine zarar veren çocuk ve gençlerde aile ile olan ilişkide, karar verme süreçlerinde, aile bağlanması ve problem çözmede yazınla uyumlu şekilde sorunlar mevcuttur. Kendine zarar veren çocuk ve gençlerin bu alanlarda desteklenmesi tedavinin bir parçası olmalıdır.
Surgical Management of Basilar Invagination: Comparison of Clinical and Radiographic Outcomes Utilizing Differing Surgical Approaches
Authors: SANDAL Evren , KINALI Burak , KARADAG Ali , ÇAĞLI Sedat
Published: May 2023

Aim: Previous studies have outlined various surgical approaches to treatment of basilar invagination, but none have compared multiple different treatment options using objective clinical and radiological criteria.

Material and Methods: We retrospectively reviewed the records of 30 patients with basilar invagination treated by five different surgical approaches. The surgical outcomes were evaluated and compared using objective clinical (Ranawat score) and radiological parameters (Chamberlain distance, atlantodental interval, and craniovertebral angle).

Results: Our results show a statistically significant improvement in the Ranawat score for patients undergoing 1) anterior decompression with posterior stabilization, 2) posterior decompression with posterior stabilization, and 3) the Goel procedure (posterior decompression, posterior reduction, cage distraction, and posterior stabilization). Of these, the Goel procedure produced the most significant improvement in functional and radiographic outcomes. Neither group without posterior stabilization (posterior decompression alone or endoscopic transnasal odontoidectomy alone) had a significant improvement in Ranawat score or radiographic outcomes.

Conclusion: For surgical management of basilar invagination, a combination of posterior decompression, posterior reduction, cage distraction, and posterior stabilization yielded the best clinical and radiological outcome. There is a risk of craniocervical instability and kyphosis and recurrence of stenosis in patients treated surgically without posterior stabilization. Therefore, when deciding on bacillary invagination surgery without posterior stabilization, it should be carefully considered.
Double-J Stentlerin Erkek Cinsel Fonksiyonu Üzerine Etkisi
Authors: ŞİRİN Mehmet Emin , KARAASLAN Mustafa , ÖLÇÜCÜOĞLU Erkan , POLAT Muhammed Emin , YILMAZ Mehmet
Published: May 2023

Amaç: Bu çalışmamızla URS/RIRS sonrası çok sık kullanılan double-J stentler’in (DJS) erektil fonksiyon üzerine etkisini araştırarak literatüre katkıda bulunmayı amaçladık.

Gereç ve Yöntemler: Bu retrospektif çalışmada, üreter ve/veya böbrek taşı nedeniyle yapılan URS/RIRS sonrası DJS uygulanan erkek hastalar yer almaktadır. Hastaların stentli iken ve stent çıkarıldıktan sonraki İİEF-5 skor değişimi ile demografik verileri, alfa blokör kullanımı, cerrahi türü, IPSS, İİEF-5, VAS skoru ve stent takılı kalma süresi univariate analiz ile değerlendirildi. p
As práticas corporais de aventura nas aulas de Educação Física escolar: uma revisão de escopo
Authors: França Dilvano Leder de , Rocha Adair José Pereira da , De Oliveira Valdomiro , Vagetti Gislaine Cristina
Published: May 2023

Introdução: as práticas corporais de aventura compreendem diferentes práticas que são realizadas em contato com a natureza, porém ainda são um conteúdo pouco estudado e desenvolvido no contexto escolar. Desde 2017, entretanto, o tema está presente nos documentos que norteiam o ensino da Educação Física escolar. Sendo assim, é importante compreender os objetivos, resultados e conclusões que estudos mais recentes apontam sobre essas práticas. Objetivo: caracterizar a produção científica do conhecimento sobre as práticas corporais de aventura nas aulas de Educação Física escolar nos últimos 10 anos, de 2012 a 2022. Método: trata-se de um estudo de revisão de escopo no qual utilizaram-se os seguintes descritores: práticas corporais de aventura, esportes de aventura, esportes radicais, atividades de aventura, esportes na natureza, Educação Física, Educação Física escolar e escola, considerando os artigos publicados desde 2012 disponíveis em diferentes bases de dados. Resultados: foram identificadas 33 publicações que tratam das práticas corporais de aventura no contexto escolar, sendo eleitos 22 estudos para análise. Os resultados apontam para uma escassez de estudos originais sobre o tema nas aulas de Educação Física, além de diversas possibilidades e dificuldades no ensino dessas práticas no ensino escolar. Conclusão: as práticas corporais de aventura contemplam uma série de possibilidades e desafios que necessitam de novos estudos para sua compreensão no âmbito escolar.
Estado do conhecimento: teoria e prática, a expertise de três pesquisadoras
Authors: Vega Antonio Paulo Valim
Published: May 2023

Resenha do livro Estado do Conhecimento: teoria e prática
Sense Líquen: uma proposta para trabalhar com números e quantidades
Authors: Zancan Sabrina , Berticelli Danilene Gullich Donin
Published: May 2023

Cartazes de números e quantidades são muito comuns e estão presentes em muitas salas de aula do Ensino Fundamental I. Geralmente coloridos e com figuras diversas, buscam representar os números em forma de algarismos, por extenso e com desenhos representando as quantidades. Neste texto, apresentamos uma proposta alternativa de representar os números e as quantidades, uma forma desenhada e outra manipulativa, que pode ser utilizada para representação de quantidades ou para resolução de operações de adição e subtração, a qual denominamos Sense Líquen. O Sense Líquen facilita o processo de ensino e aprendizagem na construção da relação entre números e quantidades, valoriza as relações numéricas e leva os estudantes a perceberem que os números se relacionam, que um está dentro do outro, ou que um contém o outro. Permite a visualização de números e quantidades sem a necessidade de contagem, a resolução de operações de adição e subtração estabelecendo e valorizando as relações numéricas, o senso numérico, a criatividade e a flexibilidade com os números. O material favorece a construção de conhecimentos necessários para a elaboração de estratégias de cálculo mental, essenciais para resolver situações-problema do dia a dia.