bluuebunny/crossref_metadata_2025 huggingface dataset:
Validity and Reliability of the Acceleration-Speed Profile for Assessing Running Kinematics' Variables Derived From the Force-Velocity Profile in Professional Soccer Players
Authors: Alonso-Callejo Antonio , García-Unanue Jorge , Guitart-Trench Marc , Majano Carlos , Gallardo Leonor , Felipe Jose Luis
Published: October 2023

Alonso-Callejo, A, García-Unanue, J, Guitart-Trench, M, Majano, C, Gallardo, L, and Felipe, J. Validity and reliability of the acceleration-speed profile for assessing running kinematics' variables derived from the force-velocity profile in professional soccer players. J Strength Cond Res XX(X): 000–000, 2023—This research aim to assess the validity and reliability of the acceleration-speed profile (ASP) for measuring the mechanical variables of running kinematics when compared with the force-velocity profile (FVP) obtained by reference systems. The ASP and FVP of 14 male players of an elite football club were assessed during a competitive microcycle. Three ASPs were tested according to the number and type of sessions included in its plotting (ASP1: 5 training sessions and competitive match; ASP2: 5 training sessions; ASP3: competitive match). Force-velocity profile was tested 4 days before match (MD-4) with a 30-m linear sprint using 3 previously validated devices (encoder, mobile App, and global positioning system). Level of significance was p < 0.05. Acceptable reliability (intraclass correlation coefficient > 0.5) was found between the ASP1 and the encoder for all variables (F0-A0, V0-S0, and Vmax). The more reliable ASP method was the ASP1 showing a lower bias than the ASP2 and ASP3 methods for almost all variables and reference systems. For ASP1, lower mean absolute error (MAE: 0.3–0.5) and higher correlation (P-M corr: 0.57–0.92) were found on variables related to the velocity in comparison with variables related to the early acceleration phase (F0-A0; MAE: 0.49–0.63; P-M corr: 0.13–0.41). Acceleration-speed profile, when computed with data from a complete competitive week, is a reliable method for analyzing variables derived from velocity and acceleration kinematics. From these results, practitioners could implement ASP and the applications of the FVP previously studied, such as resistance training prescription, performance assessment, and return-to-play management.
An Overview on the Dispersion of Steel Fiber in Ultra-High-Performance Concrete
Authors: Dong Enlai , Fan Dingqiang , Ma Xianwei , You Peibo
Published: October 2023

Ultra-high-performance concrete (UHPC) is widely recognized for its high toughness, which is directly affected by the dispersion of steel fiber and its loading mode. To investigate the reinforcement effect of steel fiber, this paper summarizes the influencing factors, evaluation methods, and theoretical models of steel fiber dispersion in UHPC. First, the results reveal that a scientifically designed mixture can reduce the cost of steel fiber dosage in UHPC and improve fiber dispersion by adjusting matrix rheological properties. The optimum plastic viscosity of the slurry should range from 30 to 80 Pa·s for achieving the best fiber dispersion effect. Second, during slurry placement, the orientation of fibers in UHPC can be improved by up to 80 % through flow induction and the wall effect, which increases the bending strength, tensile strength, and toughness of UHPC matrix by 5–67 %, 30–90 %, and 13–200 %, respectively. Moreover, although the dispersion of fiber in two-dimensional space has been extensively studied, further characterization in three-dimensional space is required. Lastly, some theoretical simulation results have been achieved on fiber orientation, but factors such as aggregate or reinforcement must be considered.
Tuned to Tremor: Increased Sensitivity of Cortico-Basal Ganglia Neurons to Tremor Frequency in the MPTP Nonhuman Primate Model of Parkinson's Disease
Authors: Rahamim Noa , Slovik Maya , Mevorach Tomer , Linkovski Omer , Bergman Hagai , Rosin Boris , Eitan Renana
Published: October 2023

Rest tremor is one of the most prominent clinical features of Parkinson's disease (PD). Here, we hypothesized that cortico-basal ganglia neurons tend to fire in a pattern that matches PD tremor frequency, suggesting a resonance phenomenon. We recorded spiking activity in the primary motor cortex (M1) and globus pallidus external segment of 2 female nonhuman primates, before and after parkinsonian state induction with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. The arm of nonhuman primates was passively rotated at seven different frequencies surrounding and overlapping PD tremor frequency. We found entrainment of the spiking activity to arm rotation and a significant sharpening of the tuning curves in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine state, with a peak response at frequencies that matched the frequency of PD tremor. These results reveal increased sensitivity of the cortico-basal ganglia network to tremor frequency and could indicate that this network acts not only as a tremor switch but is involved in setting its frequency.

SIGNIFICANCE STATEMENTTremor is a prominent clinical feature of Parkinson's disease; however, its underlying pathophysiology is still poorly understood. Using electrophysiological recordings of single cortico-basal ganglia neurons before and after the induction of a parkinsonian state, and in response to passive arm rotation, this study reports increased sensitivity to tremor frequency in Parkinson's disease. We found sharpening of the population tuning to the midrange of the tested frequencies (1-13.3 Hz) in the healthy state that further increased in the parkinsonian state. These results hint at the increased frequency-tuned sensitivity of cortico-basal ganglia neurons and suggest that they tend to resonate with the tremor.
Early Action Error Processing Is Due to Domain-General Surprise, Whereas Later Processing Is Error Specific
Authors: Choo Yoojeong , Mather Alec , Wessel Jan R.
Published: October 2023

The ability to adapt behavior after erroneous actions is one of the key aspects of cognitive control. Error commission typically causes people to slow down their subsequent actions [post-error slowing (PES)]. Recent work has challenged the notion that PES reflects adaptive, controlled processing and instead suggests that it is a side effect of the surprising nature of errors. Indeed, human neuroimaging suggests that the brain networks involved in processing errors overlap with those processing error-unrelated surprise, calling into question whether there is a specific system for error processing in the brain at all. In the current study, we used EEG decoding and a novel behavioral paradigm to test whether there are indeed unique, error-specific processes that contribute to PES beyond domain-general surprise. Across two experiments in male and female humans (N= 76), we found that both errors and error-unrelated surprise were followed by slower responses when response–stimulus intervals were short. Furthermore, the early neural processes following error-specific and domain-general surprise showed significant cross-decoding. However, at longer intervals, which provided additional processing time, only errors were still followed by post-trial slowing. Furthermore, this error-specific PES effect was reflected in sustained neural activity that could be decoded from that associated with domain-general surprise, with the strongest contributions found at lateral frontal, occipital, and sensorimotor scalp sites. These findings suggest that errors and surprise initially share common processes, but that after additional processing time, unique, genuinely error-specific processes take over and contribute to behavioral adaptation.

SIGNIFICANCE STATEMENTHumans typically slow their actions after errors (PES). Some suggest that PES is a side effect of the unexpected, surprising nature of errors, challenging the notion of a genuine error processing system in the human brain. Here, we used multivariate EEG decoding to identify behavioral and neural processes uniquely related to error processing. Action slowing occurred following both action errors and error-unrelated surprise when time to prepare the next response was short. However, when there was more time to react, only errors were followed by slowing, further reflected in sustained neural activity. This suggests that errors and surprise initially share common processing, but that after additional time, error-specific, adaptive processes take over.
The Impact of Environmental Performance and Environmental Disclosures on Economic Performance
Authors: Mar'ati Fudji Sri , Darsono Darsono
Published: October 2023

Purpose : This study aims to ascertain how economic performance is impacted by environmental performance and environmental disclosures.Method : The study population consists of LQ45-indexed enterprises registered on the Indonesia Stock Exchange between 2015 and 2019. With a total sample size of 65 financial statement data and annual reports, they were ascertained using the purposive sampling technique. SEM-PLS (Structural Equation Modeling based on Partial Least Squares) data analysis methods with SmartPLS 3.3 were employed for this investigation.Findings : Environmental performance significantly negatively affects economic performance, according to an examination of a study on 13 companies indexed LQ45 in 2015–2019 with 65 financial statement data and annual reports. Ecological transparency, nevertheless, has a very good implication for economic performance. The results of this study have significance for LQ45 firms listed on the Indonesia Stock Exchange, helping them become more environmentally conscious. It can be a strategy for LQ45 companies to get PROPER awards from the government. Additionally, it can serve as a guide when creating environmental rules. Novelty : This study is to measure the economic performance that can be seen from the practice of work on the results of the value of environmental disclosure and environmental performance. This study also explores environmental performance (X1) and environmental disclosure (X2). This study formulates the relationship between environmental performance and the company’s economic performance. And a study of the relationship of environmental disclosure with the company’s economic performance. So that the resulting hypothesis is stronger and more accurate about economic performance resulting from environmental disclosure and environmental performance.Keywords : Economic Performance; Environmental Performance; Environmental Disclosure; LQ45 Companies
Seed germination ability and biochemical features of two Teucrium taxa (germander) of Lamiaceae
Authors: Dönmez Şirin , Önal Fatma
Published: October 2023

Teucrium chamaedrys subsp. chamaedrys and Teucrium polium, from the Lamiaceae family, have ornamental, medicinal, and aromatic usage potentials. In this study, seed germination and biochemical features of samples of two taxa grown in natural habitat and cultivated were determined. Seed germination tests were carried out in petri dishes. Phenological and biochemical characteristics were performed on the seedlings and grown in viols obtained from two different origins. While germination rate was between 41% and 46% in T. chamaedrys, it was 33% in T. polium. In T. chamaedrys the seedling raising rate was between 16% and 26%, however, it was determined as 33.3% and 26.7% in T. polium, natural and cultivated plants, respectively. In terms of macro and micro elements, no statistical difference was observed in seedlings of both origins. Germacrene-D was determined with the highest amount in T. chamaedrys as 41.1% in natural plants seedlings and 40.46% in the cultivated ones. Moreover, β-myrcene in T. polium was found to be the major component in both seedlings as 20.2% and 23.4%, respectively.
Comparative study on the chemical composition and biological activity of polyphenolic extracts obtained from Maclura pomifera (Raf.) C.K. Schneid bark and periderm
Authors: Coman Năstaca-Alina , Babotă Mihai , Nădășan Ingrid , Dinică Ștefania , Ștefănescu Ruxandra , Frumuzachi Oleg , Man Adrian , Mocan Andrei , Tanase Corneliu
Published: October 2023

Literature is limited regarding the potential use of the bark of Maclura pomifera as a source of bioactive compounds. The influence of different extraction methods was assessed for the chemical and biological properties of extracts obtained from the bark and periderm of M. pomifera. The extraction process was completed using three methods: microwave-assisted extraction (MAE), ultrasound-assisted extraction (UAE), and sonicator-assisted extraction (SAE). The extracts were characterized by total polyphenol content. The antioxidant capacity was evaluated using DPPH and ABTS methods, the antimicrobial effect was tested against Gram-positive and Gram-negative bacterial strains, and the inhibition of enzyme activity was conducted using α-glucosidase, lipase, and α-amylase assays. The extracts obtained from the periderm exhibited a lower total polyphenolic content compared to those obtained from the bark. The highest antioxidant activity using the DPPH method was observed in the MAE bark extracts and when using the ABTS method, and the highest activity was observed in the UAE bark extracts. Enzymatic activity was most strongly inhibited by the SAE bark extract. The most pronounced antibacterial potential was observed in the MAE and UAE bark extracts, with minimum inhibitory concentration values obtained below 1 mg/mL.
An Experimental Study on the Cooling Performance of Refrigerant (R134a/R1234yf) in Automobile HVAC System
Authors: CS Rajamanickam , P Tamil Selvan
Published: October 2023

The present work deals with the experimental investigation on the performance evaluation of R134a and R1234yf as automotive HVAC refrigerants. As the usage of R134a increases environmental issues due to its higher global warming potential (GWP), it is necessary to find an alternative without compromising the performance of the HVAC system. R1234yf having low GWP is one such drop-in alternative. But the COP of the system using R1234yf is observed to be low. Hence this work investigates on the effects of using an internal heat exchanger (IHX) with the conventional automotive HVAC system in the performance enhancement. The results indicate acceptable range of cooling capacity, COP and compressor discharge temperature for R1234yf when integrated with IHX and a high efficiency evaporator. COP of the R1234yf IHX system is observed to higher than the COP of R134a baseline system. The results of cooling capacity and compression discharge temperature of R1234yf IHX system also shows an enhancement and matches with the corresponding values of R134a baseline system.
Exploring Students' Financial Willingness for Online Mental Health Counseling Services
Authors: Mirawati Ira , Wirakusumah Teddy Kurnia , Rahmawan Detta
Published: October 2023

Mental Health Consultation Services are widely available in Indonesia, comprising both professional consultations led by psychologists and peer counseling services. While professional services have set fees, peer counseling is offered free of charge. However, all services involve operational costs, such as website and application maintenance, internet and mobile credit for peer counselors, and training expenses. This research aims to explore students' willingness to incur costs for seeking consultation. The research employed a survey with 101 respondents and interviews with selected samples. The findings indicate eight aspects influencing students' readiness to pay for online mental health consultations. These aspects include client awareness of application operational costs, willingness to donate, response, expertise, determination of donation amounts, payment timing, and payment methods.
To The Question about the Sources of the "Canon of Medicine" By Abu Ali Ibn Sina
Authors: Karimova Surayyo Ubaydullaevna
Published: October 2023

The great polymath of the Middle Ages Abu Ali Hussein ibn Abdallah ibn Sina (980-1037) (Avicenna) in the history of mankind is better known as a brilliant physician. His vast knowledge, advanced ideas and practical innovations are reflected in his famous medical encyclopedia "The Canon of Medicine" (Kitab al-qanun fi-t-tibb), used in medical practice and education as the most complete and fundamental work in both Muslim East as well as in Europe. The article attempts to determine the circle and number of authors, and written sources used by Avicenna, identify them, and also show his attitude towards them through their citation in all five books.
An explorative study to assess the factors influencing well-being of patients with End Stage Renal Disease (ESRD) undergoing hemodialysis at dialysis units of selected hospitals of Bagalkot
Authors: Torvi Miss. Janhavi P , Joseph Treesa , Natekar Deelip S , P Ashpak , . Arun , M Rekha , O Sachin , . Jicksy , B Megha
Published: October 2023

Background: Kidneys are paired organ, occupying the lower position in the body and performing the upper most roles in homeostasis. Nowadays, chronic kidney disease (CKD) has been increasing due to various factors. Chronic Renal Failure is defined by the level of kidney function and the evidence of kidney damage. End Stage Renal Disease (ESRD) is a known increasing public health concern globally. The irreversible advanced CKD leads to End Stage Renal Disease (ESRD) where there is permanent loss of kidney function causing extreme mortality rates among this population1 Objective: Find the factors influencing wellbeing of patients with End Stage Renal Disease (ESRD) undergoing hemodialysis. Methods: This cross-sectional study included a sample of 100 patients with End Stage Renal Disease (ESRD) undergoing hemodialysis at Hanagal Shri Kumareshwar Hospital and Research Centre, Bagalkot and District Government Hospital, Bagalkot. Data were collected using self report method and Hospital’s records. Tools used for data collection were; socio-demographic questionnaire, Ryff’s Psychological Wellbeing scale and Centre for Epidemiologic Studies Depression Scale (CES-D Scale), Generalized Anxiety Disorder Scale – 7 (GAD-7). Multiple linear regression analysis was performed to find the significant predictors of Psychological Wellbeing. Results: A significant regression equation was found (F16, 99=4.5, R2=0.46, P=0.000).  Social Support has positively predicted the Psychological Wellbeing of patients with End Stage Renal Disease (ESRD) undergoing      hemodialysis. Depression and Anxiety was the strongest negative predictors of Psychological Wellbeing of patients with End Stage Renal Disease (ESRD) undergoing      hemodialysis. Conclusion: Interventions aimed at management of depression, anxiety and strengthening of social support among patients with End Stage Renal Disease (ESRD) undergoing      hemodialysis would result in enhancement their Psychological Wellbeing.
Effectiveness of animation distraction on pain response among preschool children during venipuncture in selected hospitals at Bagalkot
Authors: Hiremath Sangamma , Teli Shridevi , Natekar Deelip S
Published: October 2023

Background:  Today’s society is complex and ever changing children need to grow and learn many things. Children are vulnerable  to different forms of illness, hospitalization is one of the stressful event in child life . Venepuncture is an invasive procedure in hospital settings. Which may produce pain, anxiety, and discomfort in children. The animation destraction is one of the effective method which helps to reduce the pain stimuli. Objectives:  To assess the pain perceived by the pre school children during venipuncture in both experimental and control group.   Methods : A Quasi experimental  study with sample of considered of 60 pre school children (30 sample in the control group ,30 sample in experimental group) selected by inclusion or exclusion of samples  from the target population.  FLACC SCALE was used to  assess the pain level. The data was entered in the MS excel  sheet  and transffered  to SPSS 18 for  analysis .   Result : The mean value of experimental group of pain score during venipuncture 2.8± 1.03 and control group pain score during venipuncture7.9±0.71.The mean pain score between  the control group and experimental group 5.1,P<0.001. Conclusion :  Mean score of control group is greater than mean score of experimental group. This study found that animation distraction is one of the effective nursing intervention in reducing the pain level among pre school children during venipuncture .
Alcaftadine 0.25% Vs Olapatadine 0.2% Ophthalmic Solutions in Allergic Conjunctivitis: A Study in a Clinical Setting in South India
Authors: R Akash , Veeramani Panimalar A , G Taarika
Published: October 2023

Objective: Although allergic conjunctivitis seldom causes visual impairment, it holds significance due to its frequency and severity. This study was carried out to compare the safety and efficacy of Alcaftadine 0.25% and Olapatadine 0.2% ophthalmic solutions in treating the symptoms and signs of allergic conjunctivitis as there is not much literature comparing these two drugs directly. Materials and methods: This is a prospective, observer masked study of 80 patients with allergic conjunctivitis assigned to two groups-Group I: 40 patients received Alcaftadine 0.25% and Group II:40 patients received Olapatadine 0.2% ophthalmic solution and relief of symptoms were noted and assessed with a follow at 1 week and 1 month. Results: Eyes treated with Alcaftadine 0.25% had significantly low mean itch score of 0.6 compared to Olapatadine 0.2% ophthalmic solution which was 1. Eyes treated with both Alcaftadine 0.25% and Olapatadine 0.2% ophthalmic solutions reduced lid swelling, redness and discharge; safe and no serious adverse effects were encountered. Conclusion: BothAlcaftadine 0.25% and Olapatadine 0.2% ophthalmic solutions used in the study are safe and effective in treating the symptoms and signs of Allergic conjunctivitis. However, Alcaftadine 0.25% ophthalmic solution is comparatively more efficacious.
Role of Visual Acuity & Contrast Sensitivity in Early Diagnosis of Cognitive Impairment in Parkinson’s Disease
Authors: R Akash , Reddy Chiramana Supreeth , Ramakrishnan Abinaya
Published: October 2023

The study aims to evaluate the role of visual acuity and contrast sensitivity in early diagnosis of cognitive impairment in Parkinson’s disease. This cross sectional study was performed us- ing validated assessments on cognitive function using Mini Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA). Visual acuity was assessed using LogMAR and contrast sensitivity using the Pelli-Robson test. Anxiety and depression were assessed using the Hospital Anxiety and Depression Scale (HADS). One hundred patients presenting to the Neurology department for complaints satisfying the criteria for Parkinson’s disease at Saveetha Medical College and Hospital were randomly selected. The visual acuity and contrast sensitivity was found to be decreased in patients with low MMSE and MoCA scores, suggestive of visual function being a marker for progression of cognitive impairment in Parkinson’s disease. This could thereby be used in early diagnosis of dementia and in for- mulating a customised treatment plan for each individual. Parkinson’s disease has a deleteri- ous effect on various aspects of a person’s life, not just the motor functions. This in turn harms the day to day activities of the individuals, mainly the older age group and results in psychological disorders, like anxiety and depression. Therefore, this study aims to establish visual function as a marker for cognitive impairment in Parkinson’s disease, with the hopes of improving the quality of life of patients with this disease, thus revamping their purpose and outlook of their lives.
Keratometric Study of Cornea in Allergic Conjunctivitis Patients
Authors: Harshitha Konda , Reddy Chiramana Supreeth , R Akash
Published: October 2023

Background: To explore corneal biomechanical changes, identify related factors and determine early indicators of keratoconus (KC) development risk in allergic conjunctivitis (AC) patients. Methods: A total of 50 patients, including 20 eyes without AC and 30 eyes with AC were enrolled in this study. All patients underwent a complete ocular examination, including evaluations of clinical manifestations of AC, corneal tomography and densitometry by Pentacam, corneal biomechanics by Corvis ST, and corneal and epithelial thickness mapping by RTvue optical coherence tomography (OCT). Results: The index of surface variance (ISV), index of vertical asymmetry (IVA), keratoconus index (KI), index of height decentration (IHD) and Belin/Ambrosio enhanced ectasia total deviation index (BAD-D) were significantly higher in the AC group than in the non-allergic conjunctivitis (NAC) group (P < 0.05). The tomography and biomechanical index (TBI) was also significantly higher in the AC group (P =?0.04). The average epithelial thickness in the 2–7?mm annulus  was significantly thinner in the AC group than in the NAC group (P < 0.05). The average densitometry of the total cornea and the anterior layer were higher in the AC group than in the NAC group (P < 0.001). The ISV, IVA, KI, IHD and BAD-D were significantly correlated with the TBI and changes in corneal epithelial thickness in AC patients (P < 0.05). The changes in epithelial thickness were closely related to the eye rubbing frequency and allergic sign scores (P < 0.05). CONCLUSIONS: AC patients should be advised to routinely undergo corneal tomographic and biochemical measurements and the TBI could be used an indicator of KC devolopment risk in AC patients.
Code Switching in The Learning Process at Putra Kaili Permata Bangsa Superior Elementary School
Authors: . Iriyanti , . Nurhayati , . Lukman , . Tammasse
Published: October 2023

In the learning process at Unggulan Putra PutraKailiPermataBangsa Elementary School, many code-flipping techniques are used. This research tries to define these techniques. Descriptive analysis is the method applied in this study. The speech of the teachers at Putra KailiPermataBangsa Primary School is the data processed. Teachers at Putra KailiPermataBangsa Primary School provided the data for this study. The observation method is the one used to collect the data. Research data analysis is done using the Miles Huberman model. According to the study, teachers and pupils at Unggulan Putra KailiPermataBangsa Elementary School used standard Indonesian and switched between several dialects when speaking. Code swapping can in a variety of forms, including internal code-switching, external code switching, and multiple code switching. There are fifty-four data relating to code-switching. Internal code-switching is eighteen data, external code-switching is thirty-two data, and multi code-switching is 4 data. Code-switching functions to translate, explain, emphasize, answer, praise, ask, order, and test.
Gemcitabine (A Chemotherapy Medication) Vs. Phytochemicals Against Non-Small Cell Lung Cancer – A Computational Approach
Authors: L Sujatha P , Preetha S P , I Manikkavasagan , Devendran P , K Anbukumar , Sarkar Siddhartha
Published: October 2023

Non-small cell lung cancer is a type of lung cancer, where healthy cells in the lungs grow out of control forming a tumor or a nodule. Although small cell lung cancer and non-small cell lung cancer share few common symptoms and causes, their rate of spread or metastasis differs significantly. Targeted gene therapies involving uses of targeted drugs against specific gene or protein are increasingly being used for the treatment of lung cancer. This study aims at understanding the efficacy of the bioactive compounds over the already existing chemotherapy drug- Gemcitabine. For this study, the target receptor proteins of Non-Small Cell Lung Cancer (NSCLC) were retrieved from Protein Data Bank (PDB) and the ligand compounds were retrieved using PubChem NCBI. Based on various research studies, four target proteins from NSCLC and sixteen bioactive compounds of Curculigoorchioides (Black musale) were selected. And their effect of bioactive compounds has been studied by means of in-silico approach and further the identified potential active compounds have been compared with control. This comparative in-silico study has predicted that the bioactive principle of Curculigoorchioides has better efficacy against cancer receptors and can considered as an effective alternative drug for cancer treatment. Concluding, the present study will be useful in future for designing novel therapeutic plant-based drug with higher efficacy for the treatment of lung cancer.
Cryobiology and Cryomedicine Techniques’ Boosting in Wartime
Authors:   Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv, Goltsev Anatoliy , Bondarovych Mykola ,   Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv, Volkova Nataliia ,   Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv, Ukraine, Lutsenko Olena ,   Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv, Ukraine, Gaevska Yuliia ,   Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv, Ukraine, Babenko Natalia ,   Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv, Chelombytko Olha ,   Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv, Ukraine, Ostankov Maksym ,   Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv, Ukraine, Vvedenskyi Dmytro ,   Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv, Ukraine, Kisielova Hanna ,   Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv, Ukraine, Dubrava Tetiana ,   Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv, Ukraine
Published: October 2023

The review surveys the published data on a strong negative impact of psycho-emotional stress, which accompanies both the military servicemen and civilians of any state in martial law period. Such a load can lead to severe disorders of the systems that ensure the human body homeostatic stability, in particular to post-traumatic stress disorder. In this case human body is subjected to a state accompanied by the development of severe oncology and autoimmune diseases, as well as dysfunction of the male reproductive system. The study offers modern approaches to the treatment of the listed pathologies, most of which are based on the international experience of clinical and experimental research as well as achievements of national academic science. Special attention is paid to the development of cryobiological and cryomedical cell-tissue techniques, the use of those can be promising in the strengthening of both mental and physical health of civilian population during the wartime.
Time-Dependent Features of Mass Transfer and Transmembrane Potential in Erythrocytes During Equilibration in Cryoprotective Solutions
Authors:   Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv, Todrin Oleksandr , Timofeyeva Olena ,   Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv, Gordiyenko Olga ,   Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv, Ukraine
Published: October 2023

On the basis of the developed physical and mathematical model of mass transfer, which takes into account the transmembrane transfer of non-electrolytes, basic ions and the associated changes in the transmembrane potential, the redistribution of osmotically active substances during equilibration of erythrocytes in cryoprotective solutions was investigated. Time parameters of changes in concentrations of osmotically active substances inside and outside cells, as well as transmembrane electric potential, were calculated. It is shown that during the exposure of human erythrocytes to 1M solutions of glycerol, 1,2-propanediol (1,2-PD) and dimethylsulfoxide (DMSO), the sign of their transmembrane electric potential changes three times, and in solutions of ethylene glycol (EG) and of acetamide (AA) – once. The analysis of the obtained results showed that the most acceptable for further cryopreservation from the point of view of erythrocytes reaching a state close to equilibrium in a 1M solution of glycerol was their equilibration for 5.5 min, and in solutions of DMSO, AA, EG and 1,2-PD with the same concentration – 1 min. At the same time, the cells remain somewhat dehydrated (by 5.5–7.5%), and the concentrations of cryoprotectants inside erythrocytes change insignificantly during longer exposure. The indicated degree of dehydration does not affect cell viability, but reduces the likelihood of intracellular ice formation during subsequent freezing.
Trolox Antioxidant as a Factor in Stabilization of Human Cord Blood Nucleated Cells During Cryopreservation
Authors:   Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv, Zubov Pavlo , Zubova Oksana ,   Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv, Babijchuk Lyubov ,   Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv, Ukraine
Published: October 2023

The paper presents experimental data on the determination of preservation rate of human cord blood nucleated cells and their apoptosis/necrosis stages to determine the number of viable functionally active cells after cryopreservation in solutions with different concentrations of DMSO and the water-soluble analogue of vitamin E, the antioxidant trolox. Counting the number of human cord blood nucleated cells after freezing in media with the addition of trolox revealed their maximum preservation in the samples with 7.5% DMSO and 50, 70 or 200 μM of the antioxidant. Using the flow cytometry with the addition of the Annexin V FITC reagent, which specifically binds to phospholipids, and the DNA dye 7-amino-actinomycin D (7-AAD), it was established that trolox in concentrations of 50–70 μM provided an increase in the number of viable cells with intact membrane (AnnexinV─/7AAD─) by 12–16% compared to the control, which involved the use of only DMSO in the cryoprotective solution. The obtained results indicate the effectiveness of using the antioxidant trolox and the prospects of developing trolox-containing cryoprotective mixtures for freezing and long-term storage of nucleated cord blood cells, including hematopoietic progenitor cells.
Soybean (Glycine max) Purple Syndrome and its relationship with bioclimatic variables
Authors: Lavilla M. , Ivancovich A. , Díaz Paleo A.
Published: October 2023

Introduction. Cercospora leaf blight (TFC) and purple seed stain (MPS) are two endemic soybean (Glycine max) diseases in Argentina. Objective. Select the bioclimatic variables (VB) related to severity values greater than or equal to 90 % of the TFC and/or incidence greater than or equal to 50 % of the MPS in Argentina. Materials and methods. In the soybean region of Argentina during the years 2015 and 2023, 45 VB available in Worldclim (temperatures, precipitations and radiation) were used for modeling with the MaxEnt program. From the maps obtained in the
modeling, the probabilities of a severity (SEV) of TFC ≥ 90 % and/or an incidence (I) of MPS ≥ 50 % were extracted for each geographical point evaluated in this experience, to later use them in the analysis. generation of multiple linear regressions. Results. Of the 45 VB analyzed, the ones that were most related to both diseases were rainfall and temperatures. Radiation was the VB with the least association both with the SEV of the TFC and with the I of the MPS Conclusion. The bioclimatic variables temperatures (between 25 °C and 30 °C) and rainfall between the months of December to April had the greatest associations with severity values greater than or equal to 90 % of the TFC and/or incidence greater than or equal to 50 % of the MPS in Argentina.
Evaluación de carne de conejo marinada en mostaza y en vino blanco con especias
Authors: González Balmaceda Felipe , Chacón-Villalobos Alejandro , Pineda-Castro María Lourdes
Published: October 2023

Introducción. Desarrollar nuevas opciones comerciales puede generar beneficios al mercado de carne de conejo. Objetivo. Evaluar características sensoriales, fisicoquímicas y microbiológicas de dos preparaciones marinadas de carne cunícola en mostaza y vino blanco con especias. Materiales y métodos. La investigación, realizada en Costa Rica, implicó un estudio de almacenamiento en refrigeración, con dos productos marinados de carne cunícola: con mostaza y con vino con especias. Se evaluó un recuento total de psicotrofos anaerobios, rendimiento, color, pH, textura, y el agrado sensorial con 100 consumidores. Resultados. No existieron diferencias (α>0,05) en el rendimiento. Se obtuvieron valores de pH más bajos que los reportados en conejo fresco, para la preparación con vino, que tuvo cargas de UFC/g de psicotrofos anaerobios menores (p>0,05), lo cual le dio mayor estabilidad y permitió almacenarla hasta 28 días sin sobrepasar 106 UFC/g. Se obtuvo un L* alto para ambas preparaciones. En todos los parámetros de color existieron diferencias significativas según el método de preparación (p<0,05), y para L*, b* y C, existió una interacción entre los factores tiempo y el marinado. En cuanto a textura, no hubo diferencias (p>0,05) según el marinado, pero sí entre este método y el tiempo para la fuerza de corte, dureza, masticabilidad y elasticidad. La preparación no afectó los parámetros de textura con respecto al conejo sin marinar. Ambas preparaciones tuvieron una buena aceptación sensorial. Conclusión. Los procesos de marinado con mostaza y vino con especias generaron productos con alta aceptación sensorial y con características fisicoquímicas y microbiológicas apropiadas.
Cobertura del suelo sobre la concentración de nutrientes en un agroecosistema en Napo, Ecuador
Authors: Abril Saltos Ricardo Vinicio , Changoluisa Vargas Daysi , Morell Perez Leobel , Toscano Guatatoca Mayerling Kirina , Pérez Tuti Brigitte Tatyana
Published: October 2023

Introducción. La pérdida de nutrientes en diferentes coberturas de suelo, genera una disminución de la productividad en sistemas agroforestales en los bosques tropicales. Objetivo. Determinar el efecto durante dos años de la cobertura del suelo sobre la concentración de nutrientes en el agroecosistema del Centro Experimental de Investigación y Producción Amazónica. Materiales y métodos. El estudio se desarrolló en el Centro Experimental de Investigación y Producción Amazónica en Napo, Ecuador. Se establecieron dos parcelas de bosque primario con coberturas: a) guabas (Inga sp.) y b) melastomatáceas. Se realizaron dos muestreos aleatorios de suelo, uno en el año 2019 (cuatro muestras por cobertura) y otro en el año 2021 (seis muestras por cobertura), se analizaron las concentraciones de nitrógeno, fósforo, potasio, calcio y materia orgánica. Se aplicó un análisis de varianza para determinar diferencias significativas entre las coberturas y los períodos de muestreo. Se realizó un análisis de correlación de Pearson para determinar las relaciones entre las concentraciones de los diferentes nutrientes. Resultados. Se observaron diferencias significativas (p<0,05) para las coberturas de suelo en las concentraciones de materia orgánica y fósforo, que fueron mayores en la parcela con melastomatáceas. En el año 2021 se observaron diferencias significativas para las concentraciones de potasio, fósforo y nitrógeno. La interacción año x cobertura, en la cobertura guabas, mostró un incremento de concentración de nutrientes después de los dos años. Hubo correlaciones significativas entre las concentraciones de potasio con el resto de nutrientes y de la materia orgánica con el nitrógeno. Conclusión. La cobertura de suelo influyó sobre la concentración de nutrientes, que varió entre años. El bosque primario reportó la mayor pérdida de nutrientes y la cobertura de Inga tuvo un incremento en la concentración de estos con el paso del tiempo.
Reseña del libro Tras los rastros de un corpus seropositivo: VIH y sida en la poesída costarricense (1983-2017), de Ronald Campos López (2022)
Authors: Rojas González José Pablo
Published: October 2023

En este trabajo se reseña el libro Tras los rastros de un corpus seropositivo: VIH y sida en la poesída costarricense (1983-2017), de Ronald Campos López (2022). Primero, se expone su importancia para los estudios sobre la literatura «VIH-positiva» costarricense; además, se señala la relevancia de su tema, «olvidado» en el ámbito académico literario, y de los aportes teóricos que apoyan todo el trabajo de análisis. Luego, se ofrece una síntesis de algunos capítulos del libro de Campos López, donde se comentan las aproximaciones a los distintos poemas seleccionados por el autor. Finalmente, se concluye que el libro ofrece mucho material para la reflexión académica, pero también para la política, ya que el estudio de la literatura VIH-positiva implica también el análisis de los saberes que han construido la «enfermedad».
Problem-Based Learning about Error Detection and Correction in Locus Problems with the Aid of GeoGebra Software
Authors: Sy Nam Pham , Nguyen Ngoc-Giang , Anh Tuong Hoa , Haas Ben , Lavicza Zsolt , Kreis Yves
Published: October 2023

Problem-based learning puts students in situations that suggest problems without providing instructions and available knowledge. Therefore, when using problem-based learning, students need to be flexible, self-disciplined, active and self-occupied with knowledge and turn the knowledge
the teacher intends to impart into their knowledge. For locus problems, learners often make mistakes in predicting results. GeoGebra software has been brought into teaching and has been a great help for students in the process of detecting and correcting mistakes in locus problems. Our article
will analyze the views on problem-based learning and the scientific basis and provide a teaching process to detect and correct mistakes in locus problems with the help of GeoGebra software. In addition, we designed a teaching example that explicitly illustrates the above process. We found
that students were more interested and excited.
Promoting formative assessment practices in senior phase mathematics classrooms using meaning equivalence reusable learning objects
Authors: Adesanya Lydia Omowunmi , Graham Marien Alet
Published: October 2023

South African mathematics teachers in the Senior Phase (Grades 8 and 9) were introduced to the pedagogical tool, meaning equivalence reusable learning objects (MERLO), as a formative assessment (FA) strategy to promote and support teachers’ professional growth in using FA practices in the classroom. The cultural-historical activity theory (CHAT) and meta-didactical transposition (MDT) were used to frame the evolution process of teachers’ praxeologies. In this study we used qualitative participatory action research that encompassed 3 phases: pre-MERLO phase, MERLO workshop and post-MERLO phase. The study was conducted in the northeast of Pretoria in the Tshwane district in the Gauteng province, South Africa. Twelve Senior Phase mathematics teachers were purposively sampled in 6 public schools before the workshop training. During the workshop training, only 5 teachers participated due to the COVID-19 outbreak. The data collection techniques included pre- and post-interviews, workshop training sessions, classroom observations, field notes, teachers’ reflective journals, teachers’ lesson plans, learners’ workbooks and learners’ worksheets, and data were analysed using thematic analysis. The findings reveal that the teachers acquired adequate knowledge and skills to effectively structure and integrate the lesson plan of teachers’ didactical praxeologies as FA activities into their mathematics classrooms. The findings also reveal that the learners showed more interest and motivation, were actively involved, developed a deeper understanding of mathematics content, and showed increased autonomy in learning. Future research could involve implementing MERLO in all South African provinces and introducing MERLO to other emerging countries. However, the findings of this study are based on a limited sample of teachers and schools, and the recommendation is that, for future studies, more teachers should be involved in the MERLO professional development.
Physical Activity Might be the Protective Factor for Psychopathological Symptoms of Polish Female Teachers
Authors:   Józef Piłsudski University of Physical Education in Warsaw, Poland, Piątkowska Monika , Biernat Elżbieta ,   Warsaw School of Economics, Poland
Published: October 2023

The paper aimed to analyse the level of depression, anxiety and stress of female teachers and determine its association with the subjects’ psychosocial, sociodemographic, and lifestyle characteristics. A survey based on Depression Anxiety Stress Scale and International Physical Activity Questionnaire was carried out. Among teachers, 27.3% reported moderate or higher overall levels of negative emotional symptoms. Teachers with low physical activity level (PAL) were likelier to report higher levels of depression, anxiety, and stress than those with moderate or high PAL. The study indicates the importance of PA interventions for maintaining mental health in this group.
Perceived Parenting Styles and Attachment of Adolescents Aged 10 to 15 Years
Authors:   Paneuropean University, Bratislava, Slovakia, Čerešník Michal
Published: October 2023

The study presents conclusions of research on perceived parenting styles and attachment of adolescents attending Slovak state schools. The study aimed to investigate whether the emotional relationship with the child and work with behavioural boundaries that are the basis of parents’ parenting style relate to the degree of adolescents’ attachment. The theoretical background of the research problem was based on the theory of attachment and the theory of parenting styles. The research sample consisted of 1011 adolescents aged 10 to 15 (mean age 12.75 years, standard deviation 1.483) from all Slovak regions. Data were collected using the Parenting Style Questionnaire and the revised version of The Inventory of Parent and Peer Attachment. We assumed that the degree of adolescents’ attachment strongly relates to their perception of their parents’ parenting styles. The results were significant and indicated that the character of parenting affects the perception of the closeness of the relationship between adolescents and their parents.
Monitoring the Prevalence of Eating Disorder Symptoms in Slovak Secondary School Students
Authors:   Matej Bel Univerzity, Slovakia, Dulovics Mário , Kollárová Soňa ,   Matej Bel Univerzity, Slovakia
Published: October 2023

The study aims to analyse the risk of eating disorder emergence in secondary school students. Data were collected by questionnaire method. The questionnaire battery consisted of nominal variables and the EDE-Q Eating Disorder Examination Questionnaire scale. 776 secondary school students participated in the research. The mean age of respondents was 17. The empirical research identified 247 (31.8%) respondents displaying symptoms of eating disorders at least in one of four examined dimensions of the EDE-Q scale (Restraint, Eating Concerns, Shape Concerns, Weight Concerns). Significant differences were found in eating disorder symptoms regarding the preferred eating form. Respondents ticking the option “I buy my food” achieved the highest scores. Also, a significant difference in eating disorder symptoms was identified according to the accommodation type, where students living in “sublets” can be considered to be at the highest risk in this regard. A significant difference in the prevalence of eating disorder symptoms was also recorded in terms of gender, where girls scored statistically significantly higher than boys in the monitored dimensions.