bluuebunny/crossref_metadata_2025 huggingface dataset:
A comparative randomized study of awareness during two anesthetic induction techniques in old aged patients using isolated forearm technique
Authors: Ibrahim Tamer Hamed , Ayoub Ahmed H. , Ibrahim Ibrahim Mohamed , Abdulnaiem Ismaiel Mohamed Abdulmohsen , Mostafa Raham Hasan
Published: February 2022

Background & Objective: Awareness under anesthesia is defined as intraoperative consciousness and/or postoperative recall of surgical events. The isolated forearm technique (IFT) is a technique that has the ability to assess consciousness of the external world through a verbal command during general anesthesia. It provides live information about the presence of consciousness.

We compared inhalational induction technique versus intravenous induction technique regarding awareness during laryngoscopy and intubation in elderly patients.

Design: A prospective, randomized trial

Methodology: A total of 50 patients scheduled for elective surgery under general anesthesia; aged 60 to 80 years were recruited. Patients were randomized into either Group A (inhalational induction group) or Group B (total intravenous induction group). Awareness reaction using IFT technique was observed during laryngoscopy and intubation phase to identify awareness incidence. A patient was considered a responder if IFT score > 2.

Results: At laryngoscopy and intubation phase, 32% of cases had an awareness reaction in intravenous induction group (Group B): While in the inhalational induction group (Group A), only 8% of cases had an awareness reaction. Additionally, none of the patients, suffered from postoperative explicit recall as detected by modified Brice questionnaire (MBQ).

Conclusions: On the basis of the results of our study, we conclude that intravenous induction of general anesthesia may subject old aged patients to a higher incidence of awareness when compared to inhalational induction technique.

Trial Registration: NCT05019560

Abbreviations: TIVA - Total intravenous anesthesia; IFT - Isolated forearm technique; MBQ - Modified Brice questionnaire; BISTM -Bispectral Index™; ETAC - End-tidal anesthetic concentration; MAC – Minimum alveolar concentration

Key words: Awareness; The modified Brice questionnaire; Elderly patients; Isolated forearm technique; Sevoflurane; TIVA

Citation: Ibrahim TH, Ayoub AH, Ibrahim IM, Ismaiel MAA, Mostafa RH. A comparative randomized study of awareness during two anesthetic induction techniques in old aged patients using isolated forearm technique. Anaesth. pain intensive care 2022;26(1):81-88.

DOI: 10.35975/apic.v26i1.1772

Received: November 14, 2021, Reviewed: December 18, 2021, Accepted: December 22, 2021
Systemic thrombolysis and anticoagulation in postpartum patient with acute respiratory distress syndrome, COVID-19 and acute pulmonary embolism: a case report
Authors: Rotua Samuel Hotma , Arilaksono Dwisetyo Gusti , Hutajulu Shinta Vera
Published: February 2022

COVID-19 has a wide spectrum of clinical presentations, from asymptomatic cases to severe respiratory distress, multi-organ dysfunction, and death. Pulmonary embolism (PE) is the most feared and severe complication of venous thromboembolism (VTE). We present a case of a 25-year-old nonsmoker pregnant woman (gravida 2, no history of abortion/miscarriage), who underwent an elective cesarean section at 39 weeks of gestation after uneventful pregnancy. She exhibit clinical presentation of pulmonary embolism (PE) overlapping with severe COVID-19 pneumonia. The diagnosis was made based upon severe oxygen desaturation, McConnel sign finding on POCUS and elevated D-dimer level (34.19 µg/mL). Alteplase and low-molecular-weight heparin were used, which resulted in rapid clinical improvement. We should be warned about high or extremely elevated D-dimer levels and severe oxygen desaturation, as markers of severe COVID-19 pneumonia in patients with high clinical suspicion of PE. Thrombolysis could be an effective and safe therapy for PE in ARDS secondary to COVID-19. Furthermore, we underline that POCUS, despite its inherent limitations, could be a flexible diagnostic and management tool in refractory ARDS due to COVID-19.

Key words: COVID-19; SARS-CoV-2; Pulmonary Embolism; Thrombolysis; Postpartum; POCUS

Abbreviations: ARDS - Acute respiratory distress syndrome; PE - Pulmonary embolism; VTE - Venous thromboembolism; BPM – Beats per minute

Citation: Rotua SH, Arilaksono DG, Hutajulu SV. Systemic thrombolysis and anticoagulation in postpartum patient with acute respiratory distress syndrome, COVID-19 and acute pulmonary embolism: a case report. Anaesth. pain intensive care 2022;26(1):115-118.

DOI: 10.35975/apic.v26i1.1777

Received: September 13, 2021, Reviewed: November 06, 2021, Accepted: November 10, 2021
Professor Sajid Usman Kaul
Authors: Ali Liaqat , Taqi Arshad
Published: February 2022

Prof. Sajid Usman Kaul touched many lives during his lifetime, significant among them a group of anesthetists he recruited, nurtured, and empowered to take over when he passed the baton. Prof. Kaul became the pioneer of corporate anesthesia and pain services in Pakistan when he established Kaul Associates (Pvt) Ltd.
Microsatellite (D9S905) Instability in Two Urogenital Schistosomiasis Patients with Abnormal Squamous Cells in the Urine
Authors:   Public Health and Epidemiology Department, Nigerian Institute of Medical Re-search, P.M.B. 2013, Yaba, Lagos, Nigeria., Akinwale Olaoluwa P. , Gyang Pam V. , Ajayi Morakinyo B.
Published: February 2022

Background: Schistosomiasis ranks second to malaria among parasitic diseases of socio-economic and public health importance. Schistosoma haematobium infection-causing urinary schistosomiasis is widespread in Nigeria. Literature has shown that bladder cancer of squamous cell carcinoma type could be associated with long-term S. haematobium infection. Many studies have also reported genomic alterations in cancers and have detected identical microsatellite instability in bladder cancer and corresponding urine sediment from the same patients. Therefore, this study aimed to detect microsatellite instability in genomic DNA obtained from exfoliated urine cells of S. haematobium infected participants using microsatellite marker D9S905, which is one of the genetic markers located around regions of frequent chromosomal loss in bladder cancer. Methods: Genomic DNA was extracted from urine and blood of 24 S. haematobium infected study participants. Microsatellite marker D9S905 located on locus 9q34.2 with allele size 294 base pair (294bp) was analyzed to identify genetic variation between exfoliated urine cells and corresponding blood samples from the infected participants. Result: Microsatellite alterations due to allelic loss were seen in the DNA of exfoliated urine cells of 2 of the participants. Also, previous cytopathological examinations of exfoliated urine cells of these 2 participants revealed squamous cell abnormalities. Conclusion: Bladder cancer is one of the severe complications of chronic S. haematobium infection. Since not all cases of the infection are chronic, this might have accounted for the low number of cases of microsatellite instability seen among participants in this study
Prevalence of Urogenital Schistosomiasis and its Implication on Control Efforts Among School Pupils in Ogun State, Southwest Nigeria
Authors:   Department of Zoology, University of Lagos, Akoka, Lagos State, Nigeria, Alexander Susan I. , Nwafor Timothy S. , Gyang Pam V. , Idowu Emmanuel T. , Akinwale Olaoluwa P.
Published: February 2022

Background: Schistosomiasis causes anaemia, stunting, and cognitive impairment in children, which impairs school performance. Government coordinated school-based preventive chemotherapy with donated praziquantel has been primarily used for schistosomiasis control in Ogun State, necessitating the need to monitor treatment coverage and its effect on schistosomiasis burden. Methods: We screened 422 pupils aged 1-14 years old for Schistosoma haematobium in June 2018 using the filtration technique. KAP data and socio-demographic characteristics of participants were also recorded. Results: Out of 422 screened pupils, 59 (14%) tested positive using the filtration method. Peak prevalence (31.6%) occurred in pupils under five years. Heavy infection intensity occurred in 3.4% of the infected population. KAP studies revealed that 55% knew schistosomiasis was linked to urinating blood. Symptoms experienced main-ly were diarrhoea (44.6%), stomach ache (29.7 %), and fever (13.5 %). Pipe-borne water (48.2%), well water (28.7%), and stream water (23.1%) were the major sources of water for household chores. Investigations on excreta disposal showed that 70.3% defecated in latrines, 17.3% in the bush, and 12.4% in water closets. About 54.7% had contact with a stream, while 74.2% were dewormed in the last six months. Conclusion: Children below five years old should be included in the Ogun State’s Ministry of Health’s treatment efforts. Health education should be intensified in the study areas because the population visiting streams and openly defaecating will continue undermining the Ogun State Ministry of Health’s treatment efforts. Our study will serve as an evidence base for refining control measures and effectively utilising already scarce resources.
Giant Inguinal Hernia: Two Case Reports and Literature Review
Authors:   Department of Surgery, Ekiti State University, Ado-Ekiti, Nigeria, Olaogun Julius G. , Ige Joshua T. , Kadiri Innih A. , Wuraola Obafemi K.
Published: February 2022

Giant inguinal hernia is a rare entity in developed world but are still occasionally encountered among rural dwellers in developing countries mostly as a result of ignorance, believe in alternate therapy and fear of surgery. Its management is very challenging and requires adequate preoperative preparation. We present two patients with giant inguinal herniae, one of which was left sided Amyand’s her-nia, who successfully had mesh hernioplasty in our center.
Metabolic Syndrome Associated with Polycystic Ovary Syndrome in Some Nigerian Women
Authors:   Department of Medical Laboratory Sciences, Faculty of Basic Medical Sciences, College of Medicine of the University of Lagos, Adewuni Daniel , Samuel Titilola A. , Iranloye Bolanle , Magbagbeola Olubunmi , Akinloye Oluyemi
Published: February 2022

Background: Polycystic Ovary Syndrome (PCOS) is a group of symptoms associated with endocrine disorders in women of reproductive age. Women with this syndrome is at increased risk of metabolic syndrome. This study described the metabolic syndrome and its associated components among women with PCOS in Nigerian populace. Methods: A total of 90 participants (50 PCOS and 40 controls) were recruited for the study. The diagnosis of PCOS was established using the criteria defined by International PCOS guidelines 2018. Demographic, anthropometric, and clinico-pathological data, including blood pressure, were obtained for each participant. Metabolic syndrome was diagnosed using the 2005 revised National Cholesterol Education Program Adult Treatment Panel-III (revised NCEP ATP_III) guidelines. Fasting blood glucose, insulin, total cholesterol, HDL, LDL, and triglycerides were evaluated with conventional spectrophotometric methods. Results: The prevalence of metabolic syndrome in PCOS women was 24%, with an odds ratio of 5.211, while the prevalence of 5.7% was observed in the control group. The prevalence of central obesity (waist circumference >88cm), FBS ≥100 mg/dl, HDL <50 mg/dl, triglycerides ≥150 mg/dl, and blood pressure ≥130/85 mmHg in PCOS women was 60%, 22%, 54%, 12%, and 20%, respectively. The most frequently observed individual components of metabolic syndrome were increased waist circumference and decreased HDL cholesterol. Conclusion: Metabolic syndrome and its components, especially obesity, are a major risk factor of PCOS in our population. Routine screening and modulating individual contributors of metabolic syndrome may support PCOS management.
Study of wear performance of wheel and rail steels under dry sliding conditions
Authors: Leso TP , Siyayisa CW , Mostert RJ , Moema J
Published: February 2022

The demand for efficient railway services has significantly increased in the past years due to an increased demand for the high-speed transportation of goods with high loads. The increase in loads and velocities has resulted in increased problems associated with rolling contact fatigue (RCF), rolling and sliding wear on the wheel and rail materials causing a reduction of service life of wheel/rail systems. Rail operating companies spend significant funds in maintenance and replacing damaged rails and wheels caused by wear. In addition, unscheduled maintenance due to wear and RCF often lead to poor availability of railway networks. For this study, dry sliding wear was investigated on wheel and rail steels using RTEC Multi-Function Tribometer. The results demonstrated that the rig was successful in simulating sliding wear, and that the fractions of the wear components could be varied, and it also provided instrumentation. Information on coefficient of friction against sliding distance and applied force were obtained which were used to compare sliding wear performance of both wheel and rail steels. The wheel was found to perform better than the rail under the same conditions due to its high initial hardness values and smaller interlamellar spacing.
Effect of Nanosilver Fluoride Varnish on Demineralized Primary Teeth: A Systematic Review
Authors: Aldubayyan Abdulwahab Mohammed Rashed , Alsuawari Ahmed Tarik Ahmed , Alotaibi Bassam Mansour , Almalki Hussam Abdullah Fawaz , Alkhamis Faisal Saleh , Hussein Bader Al , Ansari Dr. Shahzeb H.
Published: February 2022

Demineralization of teeth or caries is a common health problem among pediatric patients. It is a more serious issue among children from low-income households due to their lack of access to proper dental care. Silver diamine fluoride (SDF) is an effective agent used to treat demineralization, but experiments are being done to replace it with nanosilver fluoride (NSF). The purpose of this study was to assess the effectiveness of nanosilver fluoride varnish in containing demineralization of primary teeth. A systematic literature review method was used. About 15 articles met the inclusion criteria. Findings are conflicting, but most of the reviewed studies confirmed the effectiveness of an agent with nanoparticles compared to all other alternatives, especially SDF. Apart from suppressing microorganisms that cause demineralization at very low concentrations, agents with nanoparticles protect patients from discoloration of teeth and formation stains. Nanosilver fluoride varnish can be used to replace the current alternatives, but the findings should be used with caution since most of the present studies are experimental.
The Extended Person in Maya Ontology
Authors: Gillespie Susan D.
Published: February 2022

For the Maya reality is a unified whole within which every entity shares in the same fundamental animating principle. This is a relational ontology whereby no phenomenon is self-contained but emerges from relations with others, including humans and non-humans, in various fields of action.  This ontology correlates with a more encompassing “process metaphysic” in which reality is in constant flux, continually “becoming.”  The process metaphysic envisioned by philosopher Alfred North Whitehead provides a technical language for analyzing the composition and extension of Maya persons, using the model of personhood developed by anthropologist Marcel Mauss.  In life individual Maya persons assembled divergent components endowed by their maternal and paternal ancestors, which were subsequently disassembled upon their deaths.  They also assembled non-corporeal components–souls and names–that linked them to existences beyond the physical boundaries and timelines of their bodies.  Aspects of personhood were also shared by objects worn or manipulated by humans. Persons were thus extended in space and in time, outliving individual human beings. Maya belief and practice reveals the fundamental process known as k’ex, “replacement” or “substitution,” accounts for much of the flux and duration of the universe as a Maya-specific mode of “becoming.”
PROSPECTIVE DIRECTIONS OF HOTELS DEVELOPMENT AS INFRASTRUCTURAL ELEMENTS OF MICE TOURISM IN UKRAINE
Authors: Давидюк Ю. , Жалінська І. , Кравчук В.
Published: February 2022

The specific features of MICE tourism as a specialized type of tourism have been characterized and its main development trends in Ukraine have been highlighted. The state of the current infrastructure of MICE tourism – hotels and business centers, as well as the list of services provided by them in the course of servicing business tourists, have been described. The principles have been detailed, the implementation of which would lead to the development of this type of tourism and the expansion of service range, namely: an individual approach to every client, creating a unique experience for tourists, diversifying, social distancing, and authenticity. Promising areas and relevant activities have been highlighted, the implementation of which would ensure the development of Ukrainian hotels as an infrastructural element of MICE-tourism, namely: 1) rationalization of hotel management systems within the following subsystems: diagnostics of financial condition and assessment of prospects and business development, marketing, investment policy, personnel management, organizational and production management; 2) improving the quality management process of the hotel's MICE-service; 3) expansion of the hotel’s MICE-service range: business speed dating; organization and development of express programs for guests within bleisure trips (combining a business trip with a leisure trip); deluxe room (a room containing an office); 4) providing additional benefits for consumers within the framework of loyalty programs and innovative organizational and design solutions on the hotel territory, e.g. three nights for the price of two; special prices for three days before or after the scheduled date of the business trip; early check-in or late check-out; organization for corporate clients of the so-called “flexible” spaces in halls and other public areas, which would be multifunctional and easily adaptable to various formats of events; offer of free tea and coffee in the hotel lobbies; the possibility of taking all kinds of water procedures included in the price; additional discounts in themed restaurants of the city and the organization of a cultural program, etc.
San Manuel's Second Exception: Identifying Treaty Provisions That Support Tribal Labor Sovereignty
Authors: Green Briana
Published: February 2022

Inspired by the holding in WinStar World Casino, this Note considers the potential for tribes to make treaty-based arguments when facing the threat of National Labor Relations Board jurisdiction. This Note presents the results of a survey of U.S. government treaties with Native Americans to identify those treaties with language similar to that interpreted by the Board in WinStar World Casino. The survey identified four treaties and four tribes that could make treaty-based arguments like those made in Winstar World Casino: the Confederated Tribes of the Umatilla Indian Reservation, the Muscogee (Creek) Nation, the Seminole Nation of Oklahoma, and the Menominee Indian Tribe of Wisconsin. As the applicability of WinStar World Casino is narrow, this Note also considers the possibility of a broader legislative option to clarify the law and ensure labor sovereignty for all tribes.
We Need Protection from Our Protectors: The Nature, Issues, and Future of the Federal Trust Responsibility to Indians
Authors: Rey-Bear Daniel , Fletcher Matthew
Published: February 2022

The federal trust responsibility to Indians essentially entails duties of good faith, loyalty, and protection. While often thought of as unique to federal Indian policy, it developed from and reflects common law principles of contracts, property, trusts, foreign relations/international law, and constitutional law. However, several issues preclude a greater understanding and implementation of the federal trust responsibility. These include Executive Branch efforts to avoid liability, neocolonial judicial activism, and episodic congressional attention. Enactment of legislation to reaffirm and modernize the federal trust responsibility through greater self-determination, integration, elevation, oversight, and funding should help overcome these issues to improve federal Indian policy.
Brexit and the WTO: What Happens Next
Authors: Xu Andrea
Published: February 2022

In the summer of 2016, the United Kingdom (the “UK”) announced its decision to leave the European Union (the “EU”). This decision, more commonly known as “Brexit,” subsequently stirred British politics, which included Theresa May replacing David Cameron as Prime Minister. Brexit created a unique situation in European and global politics, and instigated a discussion among politicians, academics, economists, and the likes about how the UK will leave the EU and Brexit’s implications in the UK, Europe, and the world as a whole.

This Note analyzes one specific aspect of Brexit: the administrative procedures the UK must undergo to establish itself as an independent Member State in the World Trade Organization (“WTO”). This Note solely focuses on the UK’s Schedule of Concessions and considers three possible administrative proceedings that address the UK’s challenges with its Schedule of Concessions. This Note advances the argument that the most realistic administrative proceeding will be for the UK to de facto adopt the EU’s Schedule of Concessions under Article XXVI:5(c) and invoke the UK’s right to reserve to renegotiate certain provisions of its Schedule of Concessions under Article XXVIII of the 1947 General Agreement on Tariffs and Trade (the “GATT”). This procedure will allow the UK greater freedom to choose its own trade policies and draft a Schedule of Concessions in the shortest period, thus mitigating a potentially severe disruption in international trade.
Aktivitas Penyembuhan Luka Ektstrak Herba Krokot (Portulaca Oleracea)
Authors: Budiawan Antonius , Agus Purwanto  , Levi Puradewa
Published: February 2022

Krokot (Portulaca oleracea) merupakan tanaman yang secara tradisional digunakan sebagai olahan pangan dan tanaman hias. Hasil penelitian terbaru menunjukkan bahwa krokot memiliki aktivitas antibakteri yang kuat sehingga dapat dikembangkan untuk pengujian aktivitas penyembuhan luka berkaitan dengan kandungan flavonoidnya. Penelitian ini bertujuan untuk mengetahui kemampuan penyembuhan luka dan kandungan flavonoid total ekstrak herba krokot (Portulaca oleracea). Uji aktivitas penyembuhan luka dilakukan menggunakan hewan uji kelinci yang diinduksi luka dengan ukuran 8 mm. Luka kemudian dikelompokkan menjadi empat kelompok uji yaitu kelompok kontrol negatif (diberi aqua destilata), kontrol positif (diberi betadine solution), ektrak herba krokot konsentrasi 10% dan 20%. Hasil uji menunjukkan aktivitas penyembuhan luka yang berbeda signifikan dengan kelompok kontrol negatif pada kelompok yang diberi ekstrak 10 dan 20% dengan rata-rata diameter luka berturut-turut sebesar 4,14±1,30 dan 4,56±1,93 di hari ke-7, 0,81±1,40 dan 0,52±0,90mm di hari ke-11.  Uji kandungan flavonoid total ekstrak herba krokot menunjukkan rata-rata hasil 3,27±0,19 mgEQ/g.
Uji Aktivitas Antibakteri Gel Minyak Atsiri Daun Kelor (Moringa Oleifera L.)
Authors: Nurrahman Asep , Issusilaningtyas Elisa , Tia Destari MurtI
Published: February 2022

Hand sanitizer umumnya mengandung senyawa alkohol sebagai antiseptik untuk membunuh bakteri, tetapi penggunaan gel antiseptik yang mengandung alkohol dalam jangka panjang dapat menimbulkan iritasi. Oleh karena itu, diperlukan bahan alternatif alami yang ramah di kulit dan tidak mengiritasi kulit, salah satu tanaman yang memiliki daya antibakteri adalah daun kelor (Moringa oleifera L.). Tujuan penelitian ini untuk mengetahui formulasi dan uji sifat fisik dan aktivitas antibakteri gel hand sanitizer dari minyak atsiri daun kelor. Gel dibuat dalam tiga formula dengan konsentrasi carbopol yang berbeda yaitu 0,2%, 0,5%, 0,8%. Hasil evaluasi menunjukkan formula I (carbopol 0,2%) dan formula II (carbopol 0,5%) memenuhi semua syarat pada evaluasi sifat fisik gel yang meliputi uji organoleptik, homogenitas, daya sebar, daya lekat, pH, dan viskositas. Sedangkan formula III (carbopol 0,8%) tidak memenuhi uji sifat fisik yaitu uji daya sebar. Dari hasil penelitian uji antibakteri yang dilakukan diketahui bahwa minyak atsiri daun kelor konsentrasi 5% mempunyai aktivitas antibakteri terhadap Stapylococcus aureus pada dosis 2 µl, 4 µl dan 6 µl dan zona hambat minimum yang didapat yaitu 12,50 mm
Несуча здатність та деформативність елементів і конструкцій з керамзитобетону на багатокомпонентному в’яжучому
Authors: Кравченко С.А. , Постернак О.О. , Столевич І.А.
Published: February 2022

У статті наведені основні матеріали та експериментальні зразки, що використовуються у дослідженнях. Наведено основні склади керамзитобетону на багатокомпонентному в'яжучому згідно проектної міцності для виготовлення експериментальної партії елементів та конструкцій. Отримано результати експериментальних досліджень несучої здатності, деформативності та тріщиностійкості згинальних елементів, стінових блоків в натуральну величину і фрагментів стінових панелей із керамзитобетону на багатокомпонентному в’яжучому.
Bionic mechanical design and SLM manufacture of porous Ti6Al4V scaffolds for load-bearing cancellous bone implants
Authors: Bo Liao  , Cheng Xu  , Wei Li  , Dong Lu  , Zhong Min Jin
Published: February 2022

In order to repair the load-bearing cancellous bone defect of the human lower extremity, the development of a porous scaffold with high porosity, appropriate pore size, low elastic modulus and high fatigue strength has been faced with great challenges. In this study, the Ti6Al4V coaxial scaffolds with five types of beam angles and three types of pore sizes were designed using CAD and fabricated with the use of SLM. The porous characteristics and mechanical properties of scaffolds were investigated systematically. The results show that the porosity of the coaxial scaffolds is 63–69%, and the pore size is 480–700 m. Meanwihle, the elastic modulus and compressive strength of the coaxial scaffolds were 1.08–1.85 GPa, 40–88 MPa, respectively. Moreover, the fatigue strength of the coaxial scaffolds with 500–40°, 600–40°, 700–40° were 1387, 1110 and 420 MPa, respectively. The pore size and porosity of the coaxial scaffolds in our study satisfied the size requirements for bone cells growth. Meanwhile, the low elastic modulus and high fatigue strength of the scaffolds also met the bio-mechanical bearing requirements of cancellous bone implants. Our study provided a reference for the design of biomimetic cancellous bone implants with good dynamic load-bearing mechanical properties.
Trabecular bone remodelling in the femur of C57BL/6J mice treated with diclofenac in combination with treadmill exercise
Authors: Lehmann Tomasz P. , Wojtków Magdalena , Pruszyńska-Oszmałek Ewa , Kołodziejski Paweł , Pezowicz Celina , Trzaskowska Aleksandra , Mielcarek Sławomir , Szybowicz Mirosław , Nowicka Ariadna B. , Nowicki Marek , Misterska Ewa , Iwańczyk-Skalska Ewa , Jagodziński Paweł , Głowacki Maciej
Published: February 2022

Purpose: Analgesic treatment with diclofenac deteriorates bone structure and decreases biomechanical properties. This bone loss has been though to be reversed by training. The impact of exercise on bone treated with diclofenac (DF) has reminded elusive. In the present study, we assayed the combined impact of exercises and DF on mouse femur. Methods: The femur samples we obtained from 30 days treated C57BL/6J female mice. The training group ran on a horizontal treadmill at 12 m/min by 30 min a day (5% grade/slope). The group of ten mice treated with DF received the drug subcutaneously every day (5 mg/kg of body weight/day). The combined group ran on the treadmill and obtained DF. After 30 days, we sacrificed mice and studied their femurs using microcomputed tomography (µCT), dynamic mechanical analysis (DMA) and nanoindentation. Results: We observed that treadmill running and DF decreased trabecular bone volume and mineral density. Combined effect of training and DF was not additive. A significant interaction of both parameters suggested protective effect of training on bone loss provoked by DF. The femur cortical bone shell remained untouched by the training and treatment. The training and the DF treatment did not alter the storage modulus E' significantly. The unchanged storage modulus would be suggesting on the unaltered bone strength. Conclusions: We concluded that even relatively short time of training with concomitant DF treatment could be protective on trabecular bone. Although viscoelastic properties of the entire femur were not modulated, femur trabecular tissue was thinned by treatment with DF and protected by training.
Assessment of marginal integrity of five different polymers in retrograde root-end filling following apicoectomy: An in-vitro analysis with scanning electron microscope and micro-radiography
Authors: Gulses Aydin , Ayna Mustafa , Emmert Marie , Karataban Pinar , Kubel Paul , Wiltfang Jorg , Acil Yahya
Published: February 2022

Purpose: The aim of the study was to evaluate marginal adaptation properties of five different sealers used as root filling material. Materials: Apical resection was performed on 100 canals of 50 maxillary premolars in slaughtered pigs. The root end of 24 canals were retrogradely filled with Diaket™, 37 root canals with Super-EBA™ including 18 with Super-EBA™. Regular and 19 with Super-EBA™ fast, 20 canals with ProRoot® MTA and 19 canals with AH-Plus™. For quantitative examination, scanning electron microscope (SEM) analysis and for qualitative examination, microradiography was performed. Results: Diaket™ achieved an overall average of 4.872 microns gap value as the best result. The mean values of marginal gap widths of AH-Plus™ and Super-EBA™ were almost with 8.044 microns and 9.951 microns in about the same magnitude, followed by Super-EBA™ Regular with 11,560 microns. Highest marginal gap value was found for ProRoot® MTA with 18.343 microns (p < 0.001). Conclusions: Both in terms of its marginal integrity and material properties, Diaket™ is the most suitable material for retrograde obturation. A preliminary version of the current paper could be found at www.researchsquare.com/article/rs-6198/v1.
Entero-enteric intestinal invagination due to intraluminal lipoma
Authors: Serrano Borrero I , Merlo Molina S , Roldán Aviña JP
Published: February 2022

Los lipomas intestinales son tumores benignos raros, la mayoría de ellos asintomáticos y diagnosticados de modo incidental. El TAC de abdomen es la prueba de imagen que más ayuda en el diagnóstico. Su tratamiento viene determinado por la situación clínica que origine, el tamaño y su localización. Sólo deben ser resecados si producen síntomas, sobre todo en aquellos cuyo tamaño es superior a los 2 cm.
Úton a közérthetőség felé
Authors: Suba László
Published: February 2022

A szerző abból a megállapításból indul ki, hogy a hivatali kommunikációban részt vevő felek kölcsönösen érdekeltek a másik fél számára érthető üzenet megfogalmazásában. Ez nem csupán jogszabályok által előírt követelmény; a hatóságok csak akkor képesek jogkövetésre ösztönözni ügyfeleiket, ha azok teljes egészében megértik, illetve pontosan értik, amit a hivatal közölni kíván velük. E cél elérése csak közérthető kommunikáció révén lehetséges. A cikk kitér a közérthetőség meghatározására és arra is, hogy hogyan mérhető egy üzenet közérthetősége. A szerző a világban már az 1950-es évektől elindult közérthetőségi törekvésektől kezdve az európai uniós, illetve a magyarországi projekteket vizsgálja, eljutva a Nemzeti Adó- és Vámhivatal közérthetőségi programjáig, kitérve a fogyatékkal élők vagy a magyar nyelvet valamilyen okból nehezebben értők számára is könnyen érthető kommunikációs üzenetek alkalmazására. A szerző által elemzett egyik legfőbb probléma a jogi szaknyelv azon sajátsága, hogy egyrészt egyszerűen, érthetően kell fogalmazni, ugyanakkor nem szabad feladni a szakmai tartalmat és a színvonalat. Egy napjainkból való esetpélda kapcsán pedig arról is képet kaphatunk, hogyan lehet teljesen érthető mondatokkal félreérthető információkat közölni.
EMPLOYABILITY OF THE USER OPINION IN DEVELOPING A PRODUCT RECOMMENDER SYSTEM
Authors: Jain Armaan
Published: February 2022

EMPLOYABILITY OF THE USER OPINION
IN DEVELOPING A PRODUCT
RECOMMENDER SYSTEM
Mekanisme Absensi Karyawan Departemen Lab Inspection di PT. Metro Pearl Indonesia
Authors: Cendani Cindy Kafita
Published: February 2022

Adanya persaingan bisnis mendorong suatu perusahaan untuk menciptakan suatu inovasi untuk bersaing unggul dalam kondisi apapun. Salah satu cara untuk dapat mencapai perusahaan yang unggul dimulai dari diterapkannya sistem manajamen operasional dalam perusahaan tersebut. Tujuan dari penelitian ini adalah untuk mengetahui tentang Mekanisme Absensi Karyawan Departemen Lab Inspection di PT. Metro Pearl Indonesia. Mekanisme Absensi Karyawan Departemen Lab Inspection di PT. Metro Pearl Indonesia dilakukan beberapa sistem terhadap setiap laporannya, beberapa diantaranya yaitu penjadwalan jam kerja karyawan, lemburan, sistem laporan absensi harian, mingguan dan perubahan jadwal jam kerja karyawan yang tiap harinya diinput dan diupdate melalui email yang dikirimkan ke attandance dengan atas sepengetahuan dan persetujuan manajer Departemen Lab Inspection.
Prosedur Pembiayaan Kepemilikan Kendaraan Bermobil iB Di PT. Bank BRI Syariah KC Purwakarta
Authors: Ramdani Zaelani Muhamad , Siti Nurjanah Riski
Published: February 2022

Perbankan merupakan Bank yang menggunakan prinsip syariah dalam menjalankan kegiatan usahanyan dimana landasan hukum dijaalankan prinsip syariah mengacu kepada Al-Qur’an dan Hadist. Tujuan  Penelitian ini di untuk mengetahui Prosedur Pembiayaan KKB iB di Bank BRI Syariah KC Purwakarta. Penelitian ini juga mengkaji terkait persetujuan pembiayaan kredit terhadap nasabah, pindah alih kepemilikan (Take over) pada Bank BRI Syariah KC Purwakarta. Termasuk juga strategi mengenai metode yang dilakukan untuk pemberian pembiayaan kredit kepada nasabah. Penelitian ini menggunakan metode penelitian kualitatif deskriptif dengan proses teknik pengumpulan data yang digunakan adalah obsevasi, wawancara, dokumentasi di lapangan.
Analisis Tugas Dan Tanggung Jawab Islami Pada Karyawan Toko Indomaret Veteran 162 Purwakarta
Authors: Gunawan Iwan , Hapipah Siti , Siti Khoeriah Ai
Published: February 2022

Tugas dan tanggung jawab karyawan toko adalah uraian pekerjaan yang harus dikerjakan oleh karyawan toko termasuk tanggung jawabnya terhadap barang-barang yang ada di toko. Dalam hal ini, yang penulis fokuskan adalah tugas dan tanggung jawab karyawan toko Indomaret, yang merupakan salah satu ritel minimarket yang terkemuka di Indonesia. Fokus penelitian ini adalah untuk mengetahui tugas dan tanggung jawab karyawan di toko Indomaret Veteran 162 PT. Indomarco Prismatama Cabang Purwakarta, untuk mencari informasi mengenai permasalahan/ kendala yang sering terjadi, dan mencari solusi agar permasalahan pada karyawan di toko Indomaret Veteran 162 PT. Indomarco Prismatama Cabang Purwakarta dapat diselesaikan tanpa harus merugikan siapapun. Adapun hasil dari penelitian ini menunjukan bahwa pembagian tugas dan tanggung jawab karyawan di toko atau gerai Indomaret Veteran 162 sudah sesuai dengan prinsip-prinsip Islam karena tugas yang dikerjakan sesuai dengan jabatan karyawan. Selain itu di Indomaret dalam bekerja benar-benar harus menjunjung tinggi nilai-nilai kejujuran, kebenaran dan keadilan, kerjasam tim, kemajuan melalui inovasi yang ekonomis, serta sangat mengutamakan kepuasan pelanggan dalam segala aspek transaksi yang dilakukan
Tackling the inverse care law: Analysis of policies to improve general practice in deprived areas since 1990
Authors: Fisher Rebecca , Allen Lucinda , Malhotra Akanksha , Alderwick Hugh
Published: February 2022

This analysis reviews attempts to tackle inequities in the supply of general practice services in England over the past 30 years. The report looks at policies on general practice funding, workforce, premises, contracts and commissioning. It provides several recommendations for national policymakers, including: a new equity test for all new policies in general practice; an independent review of general practice funding allocations; and a long-term workforce strategy for general practice that should consider stronger central coordination and oversight of GP distribution.
Orbital Elements and Individual Component Masses from Joint Spectroscopic and Astrometric Data of Double-line Spectroscopic Binaries*
Authors: Anguita-Aguero Jennifer , Mendez Rene A. , Clavería Rubén M. , Costa Edgardo
Published: February 2022

We present orbital elements, orbital parallaxes, and individual component masses for 14 spatially resolved double-line spectroscopic binaries derived doing a simultaneous fit of their visual orbit and radial velocity curve. This was done by means of a Markov Chain Monte Carlo code developed by our group that produces posterior distribution functions and error estimates for all of the parameters. Of this sample, six systems had high-quality previous studies and were included as benchmarks to test our procedures, but even in these cases, we could improve the previous orbits by adding recent data from our survey of southern binaries being carried out with the HRCam and ZORRO speckle cameras at the SOAR 4.1 m and Gemini South 8.1 m telescopes, respectively. We also give results for eight objects that did not have a published combined orbital solution, one of which did not have a visual orbit either. We could determine mass ratios with a typical uncertainty of less than 1%, mass sums with uncertainties of about 1%, and individual component masses with a formal uncertainty of 0.01 M
⊙ in the best cases. A comparison of our orbital parallaxes with available trigonometric parallaxes from Hipparcos and Gaia eDR3 shows a good correspondence, the mean value of the differences being consistent with zero within the errors of both catalogs. We also present observational H-R diagrams for our sample of binaries, which, in combination with isochrones from different sources, allowed us to assess their evolutionary status and the quality of their photometry.
Anomalous Orbital Characteristics of the AQ Col (EC 05217-3914) System
Authors: Otani T. , Lynas-Gray A. E. , Kilkenny D. , Koen C. , von Hippel T. , Uzundag M. , Vučković M. , Pennock C. M. , Silvotti R.
Published: February 2022

AQ Col (EC 05217-3914) is one of the first detected pulsating subdwarf B (sdB) stars and has been considered to be a single star. Photometric monitoring of AQ Col reveals a pulsation timing variation with a period of 486 days, interpreted as time delay due to reflex motion in a wide binary formed with an unseen companion with expected mass larger than 1.05 M
⊙. The optical spectra and color–magnitude diagram of the system suggested that the companion is not a main-sequence star but a white dwarf or neutron star. The pulsation timing variation also shows that the system has an eccentricity of 0.424, which is much larger than any known sdB long period binary system. That might be due to the existence of another short period companion to the sdB star. Two optical spectra obtained on 1996 December 5 show a radial velocity change of 49.1 km s−1 in 46.1 minutes, which suggests the hot subdwarf in the wide binary is itself a close binary formed with another unseen white dwarf or neutron star companion; if further observations show this interpretation to be correct, AQ Col is an interesting triple system worthy of further study.
Toward Accurate Modeling of Galaxy Clustering on Small Scales: Constraining the Galaxy-halo Connection with Optimal Statistics
Authors: Szewciw Adam O. , Beltz-Mohrmann Gillian D. , Berlind Andreas A. , Sinha Manodeep
Published: February 2022

Applying halo models to analyze the small-scale clustering of galaxies is a proven method for characterizing the connection between galaxies and their host halos. Such works are often plagued by systematic errors or limited to clustering statistics that can be predicted analytically. In this work, we employ a numerical mock-based modeling procedure to examine the clustering of Sloan Digital Sky Survey DR7 galaxies. We apply a standard halo occupation distribution (HOD) model to dark matter only simulations with a ΛCDM cosmology. To constrain the theoreStical models, we utilize a combination of galaxy number density and selected scales of the projected correlation function, redshift-space correlation function, group multiplicity function, average group velocity dispersion, mark correlation function, and counts-in-cells statistics. We design an algorithm to choose an optimal combination of measurements that yields tight and accurate constraints on our model parameters. Compared to previous work using fewer clustering statistics, we find a significant improvement in the constraints on all parameters of our halo model for two different luminosity-threshold galaxy samples. Most interestingly, we obtain unprecedented high-precision constraints on the scatter in the relationship between galaxy luminosity and halo mass. However, our best-fit model results in significant tension (>4σ) for both samples, indicating the need to add second-order features to the standard HOD model. To guarantee the robustness of these results, we perform an extensive analysis of the systematic and statistical errors in our modeling procedure, including a first of its kind study of the sensitivity of our constraints to changes in the halo mass function due to baryonic physics.
Chemical Evolution of CO2 Ices under Processing by Ionizing Radiation: Characterization of Nonobserved Species and Chemical Equilibrium Phase with the Employment of PROCODA Code
Authors: Pilling Sergio , Carvalho Geanderson A. , Rocha Will R. M.
Published: February 2022

Astrophysical ices are being exposed to ionizing radiation in space environments, which trigger new reactions and desorption processes. In the lab, such processing by radiation has revealed the appearance of several new species and complements the study of the chemical evolution of icy astrophysical scenarios. Here, we develop a computational methodology that helps to clarify the chemical evolution of ices investigated experimentally under photolysis/radiolysis processes until reaching chemical equilibrium (CE). Briefly, the code (named PROCODA) solves a system of coupled differential equations and describes the evolution of the molecular abundances with the irradiation time for ices under processing by radiation. Two experimental ice samples containing pure CO2 and irradiated by two ionizing agents (cosmic rays and ultraviolet photons) were considered prototype systems. Here, we considered 11 different chemical species within the ice (four observed: CO2, CO, O3, and CO3; seven nonobserved or unknown: O, O2, C, C2, C2O, C2O2, and C2O3), 100 reaction routes (e.g., direct dissociation reactions, bimolecular and termolecular reactions) and radiation-induced desorption processes. The best-fit models provide the reaction rates, several desorption parameters, as well as the characterization of the CE phase. At CE, the percentage of nonobserved species in the UV model was almost triple the one calculated in the CR model (which also includes a lot of O and C atoms). The determined values can be employed in future astrochemical models to map chemical evolution embedded species in astrophysical regions under the presence of an ionizing radiation field.
Collisional Excitation and Non-LTE Modeling of Interstellar Chiral Propylene Oxide
Authors: Dzenis Karlis , Faure Alexandre , McGuire B. A. , Remijan A. J. , Dagdigian P. J. , Rist C. , Dawes R. , Quintas-Sánchez E. , Lique F. , Hochlaf M.
Published: February 2022

The first set of theoretical rotational cross sections for propylene oxide (CH3CHCH2O) colliding with cold He atoms has been obtained at the full quantum level using a high-accuracy potential energy surface. By scaling the collision reduced mass, rotational rate coefficients for collisions with para-H2 are deduced in the temperature range 5–30 K. These collisional coefficients are combined with radiative data in a non-LTE radiative transfer model in order to reproduce observations of propylene oxide made toward the Sagittarius B2(N) molecular cloud with the Green Bank and Parkes radio telescopes. The three detected absorption lines are found to probe the cold (∼10 K) and translucent (n
H ∼ 2000 cm−3) gas in the outer edges of the extended Sgr B2(N) envelope. The derived column density for propylene oxide is N
tot ∼ 3 × 1012 cm−2, corresponding to a fractional abundance relative to total hydrogen of ∼2.5 × 10−11. The present results are expected to help our understanding of the chemistry of propylene oxide, including a potential enantiomeric excess, in the cold interstellar medium.
L’aventure entrepreneuriale vécue par une femme
Authors: Deroo Marie-Noëlle
Published: February 2022

Que faut-il faire pour entreprendre quand on est une femme ? Braquer une banque et éliminer tous ceux qui portent une cravate ? Divorcer et donner la garde des enfants à son ex conjoint ? Acheter des Louboutin ? Ou s’appuyer sur ses paires en s’enfermant dans des réseaux féminins ? Voici le témoignage sans détour d’une entrepreneure qui s’est depuis reconvertie dans l’accompagnement… d’entrepreneur(e)s. Avec humour, sincérité et une pointe d’ironie, elle raconte comment elle a vécu les différentes phases de son aventure : de son rêve de devenir entrepreneur, en passant par le lancement et la gestion de son entreprise, jusqu’à sa décision d’abandonner, incluant ses réflexions sur ce qu’elle a appris. Elle propose également de nombreux conseils précieux aux futures femmes entrepreneurs.
How gender norms impact growth-oriented female entrepreneurs
Authors: Garcia-Quevedo Diana
Published: February 2022

L’entrepreneuriat est un terrain genré. Malgré des années de programmes et de supports adressés aux femmes entrepreneuses, elles rencontrent toujours des difficultés et des défis liés à la prédominance masculine perçue dans l’entrepreneuriat. Une étude qualitative a été conduite auprès de onze entrepreneuses orientées vers la croissance. L’article étudie comment ces femmes entrepreneuses qui sont orientées vers la croissance entrepreneuriale abordent les stéréotypes de genre dans leur business. Intériorisent-elles les normes masculines et sont-elles par conséquence confrontées à la menace de stéréotypes et au syndrome de l’imposteur ou réussissent-elles à devenir des femmes entrepreneuses à succès ? Les résultats montrent que même les plus qualifiées des entrepreneuses ne sont pas épargnées par l’influence de la norme masculine existante. Cette étude analyse les conséquences des stéréotypes et normes de genre sur l’entrepreneuriat féminin et propose des suggestions afin d’aider les femmes entrepreneuses à les surmonter.
Can women entrepreneurs thrive in Saudi Arabia?
Authors: Al-Dajani Haya , Alsahli Mashael
Published: February 2022

Alors que les stratégies actuelles de diversification économique de l’Arabie Saoudite éliminent les barrières institutionnelles à l’entreprenariat féminin, elles modifient également la ségrégation qui permettait auparavant aux femmes entrepreneurs d’obtenir certains résultats positifs. Pour comprendre comment les femmes entrepreneurs peuvent prospérer dans la « nouvelle » Arabie Saoudite inclusive, tournée vers l’avenir, nous devons réfléchir à l’« ancienne » Arabie Saoudite ségréguée par le genre. Nous avons mené une étude qualitative auprès de 30 femmes entrepreneurs pour explorer cette transition de l’ancien au nouveau. Nous mettons en évidence 5 implications managériales et entrepreneuriales des réformes de genre qui se mettent en place. De plus, cette étude spécifique à un pays et portant sur un lieu d’entrepreneuriat unique remet en question l’approche dominante centrée sur les États-Unis et l’Europe concernant le traitement des questions de genre en termes de ségrégation et d’inclusion.