bluuebunny/crossref_metadata_2025 huggingface dataset:
Inter-departmental variation in surgical treatment of proximal femoral fractures: A nationwide observational cohort study
Authors: Hernefalk Björn , Rydberg Emilia Möller , Ekelund Jan , Rogmark Cecilia , Möller Michael , Hailer Nils P. , Mukka Sebastian , Wolf Olof
Published: February 2023

Background and purpose

Hip fractures should be treated based on the best available evidence and cost-effectively to optimize the outcome for this large group of frail patients. This study examined nationwide variation in surgical methods used for hip fractures.

Methods

In this cohort study 46,243 patients ≥65 years with a trochanteric hip fracture (THF) or a femoral neck fracture (FNF) registered in the Swedish Fracture Register (SFR) between 1 January 2016 and 31 December 2020 were included. Fractures were classified according to the AO Foundation/Orthopaedic Trauma Association (AO/OTA) fracture classification system. The choice of surgical methods was assessed for each fracture type to compare national variation.

Results

21,312 THFs and 24,072 FNFs (67% women) with a mean age of 83 years (SD 8) were surgically treated. In the treatment of two-fragment THFs (AO/OTA A1) departments ranged from using 90% short intramedullary nails to 98% sliding hip screws. Treating displaced FNFs (AO/OTA B3), the proportion of hemiarthroplasty ranged from 9 to 90%, and internal fixation between 0.6 to 21%, depending on the department.

Interpretation

A mature national fracture register permits the monitoring of treatment provided and thus serves as an important aid in assessing compliance with guidelines. The large inter-departmental variation in the surgical management of hip fractures in Sweden appears unwarranted based on the current evidence, indicating a need for updated national guidelines. Further research will have to clarify the impact of this variation on mortality and re-operation rates.
The Effects Of Hydrochloric Acid, Mechanical Scarification And Hot Water On Germination Of

Parkia Biglobosa Seeds (African Locust Bean)
Authors: Tyohemba Stephen
Published: February 2023

The effect of different treatments of breaking seed dormancy of Parkia biglobosa seeds were studied at Federal University Wukari, Taraba State, which is located at north eastern region of Nigeria of Southern Guinea Savanna with coordinate’s latitude 70,51’ N-7.8500N and longitude 90, 49’ E-9.7830E, annual precipitation of 1205mm and it has an average temperature of 26.80. The research took place during the dry season December 2021 to march 2022, the response of different treatments observed showed 100% for mechanical scarification, 88% for hot water and 77.7% for HCL of 50% concentration while the untreated seed control is 66% germination respectively and the data collected when subjected to analysis of variance showed significant differences between the treatments, the seedling height, number of leaves and branches performed better than the control(untreated seeds), 50% hydrochloric acid, mechanical scarification and hot water were found to induce germination of the dormant seeds of Piarka biglobosa These methods could be applied to raise seedlings of plant for field propagation and afforestation programmes which ease the whole process.
Colonic Epstein-Barr Virus-Associated Mucocutaneous Ulcer Associated With Ulcerative Colitis
Authors: Chan Patrick P.Y. , Farzin Mahtab , Acharya Priya , Viiala Nicholas , Gilmore Andrew , Crane Harry , Henderson Christopher , Ng Watson , Williams Astrid , Connor Susan J.
Published: February 2023

Epstein-Barr virus-associated mucocutaneous ulcer is a rare lymphoproliferative disorder that occurs in immunosuppressed states that can develop in the gastrointestinal tract and mimic inflammatory bowel disease or other malignancies. We present the case of a 61-year-old man who presented with concurrent acute severe ulcerative colitis and colonic Epstein-Barr virus-associated mucocutaneous ulcer requiring rituximab therapy and a subtotal colectomy.
Medically Refractory Lymphocytic Colitis Successfully Treated With Upadacitinib
Authors: Miyatani Yusuke , Choi David , Du Xiaotang , Hart John , Rubin David T.
Published: February 2023

Lymphocytic colitis is a microscopic colitis characterized endoscopically by nearly normal-appearing colonic mucosa and histology demonstrating intraepithelial lymphocytosis. Microscopic colitis that is refractory to conventional therapies, including budesonide, is rare but challenging and with scarce evidence. Upadacitinib is a novel Janus kinase 1 selective inhibitor approved by the US Food and Drug Administration for atopic dermatitis, rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and moderately to severely active ulcerative colitis. We present the first case of lymphocytic colitis refractory to conventional and immunosuppressive therapies, which responded promptly to upadacitinib.
Współczesne wyzwania chrześcijaństwa
Authors: Doda-Wyszyńska Agnieszka , Leciejewski Sławomir
Published: February 2023

Is it possible to respond to contemporary challenges of Christianity from the meta-perspective of philosophy and cultural studies? We have divided the articles presented here into three groups: challenges faced by religion regarding science, challenges of secularisation, and challenges in the Church itself. The articles from the volume do not address these problems in totally different ways. The issues of consistency and rationality of religion become reinterpreted, for example when compared to results of empirical sciences, but also in a broadly understood public debate. We shall try to show a close relationship between the Christian religion and such phenomena as: science, media, churches, medicine, war, law, etc. Our point of departure is a search for the current function of Christianity, with the Catholic Church in the centre, but the questions transcend the present state of a particular religion.
Zanik debaty? Odmienność systemów: media – Kościół – nauka
Authors: Doda-Wyszyńska Agnieszka
Published: February 2023

The main question that the article poses is whether today there is still a possibility of media debate, for example on religion or the Church; or perhaps the system of mass media is governed by the logic of what Niklas Luhmann calls the thematic career. Mass media discuss various topics, but probably do not help to search for solutions for intra- and intersystem conflicts. According to Luhmann, mass media, politics, science and religion are autopoietic systems; they develop by their own rules. They are sensitive to external conditions, but primarily refer to what they have developed within themselves. Drawing upon Niklas Luhmann’s systems theory and using the analysis of the old debate (around Galileo), still without participation of mass media, and the current debate from 2012 when Richard Dawkins met Cardinal George Pell, I ask a question about its current shape. This is presented against the backdrop of the problem of how much the so-called synodality of the Catholic Church helps a given religion influence other social systems (such as science) and generally – social life. Why is it so difficult to fulfil the conditions of debate in the context of the three systems: religion (based on the example of the Catholic religion), media (mainly the Internet) and science? Perhaps it is because we deal with extremely different social systems which are mostly concerned with their own internal development. Moreover, the situation of reflection on the phe- nomenon of religion and social systems always becomes complicated by a specific global situation, both in the Church (e.g. synodality), and outside it (e.g. pandemic, war, new social movements).
Schelerowska kategoria resentymentu w świetle sporów o sekularyzację Zachodu
Authors: Banach Wiesław
Published: February 2023

The aim of the article is to verify the category of ressentiment developed by Max Scheler in the light of disputes about the sources and causes of secularization. The category of ressentiment is one of the most important subjects of the author’s scientific reflection, being an expression of his particular interest in the functioning of the world of values. On the other hand, the processes of secularization, which have become visible in Western societies in recent decades, are understood here as the result of a decline in interest in religious issues and the disappearance of references to the broadly understood supernatural world. The key issues concern the extent to which the phenomenological conceptual apparatus developed by Scheler can serve today as an effective tool for a fuller understanding of the essence of contemporary disputes over the secularization of the West. Thus, it seems possible to assess the topicality of Scheler’s approach to the world of values as a timeless model and point of reference in research on the changing social reality.
W zgodzie z sobą i Ewangelią. Czy możliwy jest dzisiaj udany performans religijny?
Authors: Rotengruber Przemysław
Published: February 2023

There is no doubt that the Catholic Church is in a deep crisis. On the one hand, it is internally divided between supporters of the changes initiated during the Second Vatican Council (1962–1965) and conservatives opposing these changes in the name of the (Counter-Reformation) decisions made during the Council of Trent (1545–1563). On the other hand, the Church is involved in a number of political, financial, paedophile, etc. scandals. They prove the progressive loss of contact of this institution with the world as a place to preach the Gospel. For both of these reasons, the number of believers in countries considered Catholic is steadily decreasing. The purpose of this article is to correct or supplement this diagnosis. Historically, the Catholic Church – like many other religious organizations – has never been „spotless”. However, this did not prevent Catholics from identifying themselves with this institution as the depository of the Revealed Truth. Today is different. Many of them are experiencing an identity crisis. They cannot reconcile the Gospel (which takes the form of religious dogma) with the existential and moral challenges they face every day. The subject of the research undertaken in this article is to find answers to the questions (1) about the skills that allow them to reconcile one with the other and (2) about the role of the Church in the education of the community of the faithful.
BITTERNESS AND RECOGNITION: ROOM FOR OTHERS IN THE NOVELS OF STEPH CHA
Authors: WILLEMS Brian Daniel
Published: February 2023

The novels of Steph Cha posit two key characteristics for openness toward others: bitterness and recognition. The thesis of this paper is that both characteristics must be present together in order for openness to occur. Cha’s Juniper Song detective series (2013-15), as well as her stand-alone novel Your House Will Pay (2019), foreground the role that bitterness and recognition play in an openness of Korean-Americans to other American people of color. Following the work of Jacques Rancière and Axel Honneth, bitterness is seen as a characteristic that keeps recognition from falling into the oppressive traps of one group only recognizing the pre-established modes of identity of another. Cha’s novels insist on moments of bitterness within scenes of recognition, thus showing how both characteristics, together, form an essential way for a positive openness to another to be possible. Other Korean-American authors discussed include Cathy Park Hong, Caroline Kim, and Theresa Hak Kyung Cha.
CRITICISM OF LITERATURISM IN THE 1990S: FOCUSING ON MUNHAKDONGNE
Authors: YANG Soonmo
Published: February 2023

Regarding the recent critical evaluations surrounding the Korean literature field in the 1990s, this paper argues that the criticism should be presented at a more ‘intrinsic’ and ‘reflective’ level. In particular, through 문학동네 Munhakdongne (the Literature Village) as a negative origin of today, I would like to examine the rationality of ‘literaturism’ (the art for art’s sake principle) in the 90s, which is difficult to criticize easily. This ‘rationality’ is not only one that is repeated and persuasive in today’s literature, but also one that shares much from the perspective of critically judging Munhakdongne. By critically examining the nature of this ‘rationality’ in the 1990s, this paper aims to define today’s Korean literature field and to prepare for the possibility of moving beyond it.
DEVELOPMENT OF THE KOREAN POETIC DRAMA AND THE SIGNIFICANCE OF THE POETIC DRAMA MOVEMENT
Authors: LEE Hyeon-Jeong
Published: February 2023

This paper deals with the definition and characteristics of poetic drama, and attempts to clarify the significance of poetic drama works during the time when the poetic drama movement took place. Unlike drama-poetry or plays, poetic drama is an independent art genre. It presents artistic vision through the conflict of poetics and dramas. The unity of poetic and dramatic things, which is facilitated through music, internal necessity, stage image, sound effect, and visual auditory indication, poetic drama is a part of complex art. The entire work functions as a poem and must be realized on the stage. For Choi Il-soo, in order to develop the characteristics of these poetry plays, the innatrhythm of the free verse should be embodied within these plays. He accepted Eliot’s theory and tried to establish the position that Western poetic drama works and theories are unique to Korea. This deepening perception of theory led to a poetic drama movement with the creators. In this paper, we classify its characteristics by focusing on approximately 18 poetic drama works. From 1920 to 1999, 18 representative works were classified, focusing on the completeness of the works and the remarkable artists. The characteristics of works can largely be divided into historical, narrative, reality, and philosophy. The meaning of this classification can serve as an opportunity for poetic dramas to advance into more diverse topics or forms. The poetic drama movement was dominated by critics and poets with the aim of pursuing independent Korean art works, and although it failed in performance and popularization, it was an achievement of the times to give a glimpse into the possibility of poetic drama. Poetic drama can act as a new element in the genre of poetry and drama that are losing original literary character, and there is a need to revive in Korean literature.
THE SOCIOCULTURAL FACTORS INFLUENCING THE STUDY OF KOREAN HISTORY IN INDONESIA
Authors: ROSTINEU Rostineu
Published: February 2023

The historic event of the Korean Youth Independent Movement during the Japanese colonial period in Indonesia, which involved soldiers from Korea, has become a point of interest for Indonesian people, especially Indonesian millennials and historians. Since Indonesia’s independence from the Japanese colonial rule in 1945, Indonesia has gone through various difficulties and faced political crises, just as Korea has. This article discusses the social and cultural factors, particularly Indonesian millennials’ activities and interests which influence the study of Korean history in Indonesia. At several points, this research shows that the millennials’ mastery of the Korean language is important for the development of Korean historical studies in Indonesia. Applying the desk review method, this research finds a great interest among Indonesian millennials to study Korean history. One of the encouraging factors is the role of Korean history reviewers who bring Korean historical sources closer to Indonesian audiences through seminars that are intended for not only scholars, but also other millennials and the general public. The growth of Korean language users should be an important instrument to further develop not only the study of Korean history, but also diplomatic relations between Korea and Indonesia.
Levocarnitine regulates the growth of angiotensin II-induced myocardial fibrosis cells via TIMP-1
Authors: Shu Jin , Shi Jue , Gu Yiwen , Deng Lei , Zhao Chen , Wu Chun , Zhao Jiachen , Wang Haiya , Jin Li
Published: February 2023

This study aimed to explore the effects of tissue inhibitor of metalloproteinases‐1 (TIMP‐1) on levocarnitine (LC)-mediated regulation of angiotensin II (AngII)-induced myocardial fibrosis (MF) and its underlying mechanisms. H9C2 cells were treated with AngII for 24 h to induce fibrosis. The cells were then treated with LC or transfected with TIMP‐1-OE plasmid/si‑TIMP‐1. Cell apoptosis, viability, migration, and related gene expression were analyzed. AngII treatment significantly upregulated Axl, α-SMA, and MMP3 expression (P < 0.05) and downregulated STAT4 and TIMP1 expression (P < 0.05) relative to the control levels. After transfection, cells with TIMP-1 overexpression/knockdown were successfully established. Compared with that of the control, AngII significantly inhibited cell viability and cell migration while promoting cell apoptosis (P < 0.05). LC and TIMP-1-OE transfection further suppressed cell viability and migration induced by Ang II and upregulated apoptosis, whereas si-TIMP-1 had the opposite effect. Furthermore, LC and TIMP-1-OE transfection downregulated Axl, AT1R, α-SMA, collagen III, Bcl-2, and MMP3 expression caused by AngII and upregulated caspase 3, p53, and STAT4 expression, whereas si-TIMP-1 had the opposite effect. TIMP-1 is therefore a potential therapeutic target for delaying MF progression.
Pharmacological inhibition of the ubiquitin-specific protease 8 effectively suppresses glioblastoma cell growth
Authors: Long Yu , Hu Zengchun , Yang Dian , Wang Fuqiang , Zhao Chen’ge , Zhang Yang , Zhang Yingqiu , Ma Hui , Lv Huiyi
Published: February 2023

Glioblastoma (GBM) is a malignant brain tumor. The purpose of this study is to estimate the potential effects and underlying mechanisms of a ubiquitin-specific protease 8 (USP8) small-molecule inhibitor on the phenotypic characteristics of GBM cells. The growth, migration, invasion, and stemness of GBM LN229 and T98G cells were evaluated by conducting cell proliferation, colony formation, wound healing, transwell, Ki-67 staining, spheroid formation, and ionizing radiation assays, and the results collectively showed the suppressive effects of USP8 inhibition on GBM cells. Furthermore, transcriptomic profiling of GBM cells treated with the USP8 inhibitor deubiquitinase (DUB)-IN-1 revealed significantly altered mRNA expression induced by pharmacological USP8 inhibition, from which we confirmed downregulated Aurora kinase A (AURKA) protein levels using immunoblotting assays. Our findings indicated that the proliferation, invasion, and stemness of LN229 and T98G cells were markedly suppressed by USP8 inhibition. Pharmacological USP8 suppression elicits multiple tumor-inhibitory effects, likely through dysregulating various mRNA expression events, including that of the key cell cycle regulator and oncogenic protein AURKA. Therefore, our observations corroborate the GBM-supportive roles of USP8 and suggest pharmacological USP8 inhibition is a viable therapeutic approach to target GBM. The purpose of this study was to investigate the effect and mechanism of action of the USP8 inhibitor DUB-IN-1 on GBM.
The properties of potato gluten-free doughs: comparative and combined effects of propylene glycol alginate and hydroxypropyl methyl cellulose or flaxseed gum
Authors: Chen Xueting , Gao Jingyan , Cao Geng , Guo Shule , Lu Dingning , Hu Bingbing , Yang Zuoqian , Tong Yi , Wen Chengrong
Published: February 2023

Different methods are often used to make gluten-free (GF) bread to get better bread characteristics. To explore the effects of emulsifiers and hydrocolloids on the characteristics of GF dough, different esterification levels of propylene glycol alginate (PGA), hydroxypropyl methyl cellulose (HPMC), flaxseed gum with (FG) different molecular weight, and the binary blends of HPMC/PGA and FG/PGA were added to GF dough, made with potato starch and potato protein in a ratio of 6:4. The results showed that the potato GF dough with FG and FG/PGA obtained a higher viscoelasticity than the other doughs. HPMC and FG promoted to the formation of network structure, but the network structure formed by PGA and their combination was more developed. It was found that all PGA, HPMC, FG and their combination could improve the softness of GF breads. The results provided a basis for optimizing the quality of potato GF bread.
Achieving a more diverse special education teacher workforce: guiding questions for researchers and policymakers
Authors: Cormier Christopher J. , Scott LaRon A. , Cornelius Kyena E. , Rosenberg Michael S.
Published: February 2023

Attracting, supporting, and retaining special education teachers of color (SETOCs) is critical in shaping a diverse special education teacher workforce in the United States. However, efforts to diversify this workforce are fraught with challenges at the federal, state, and local levels. This paper reviews what is currently known about efforts to attract, support, and retain SETOCs, and provides guidance for policy makers and researchers regarding what still needs to be done to realize a more diverse special education teacher workforce in the US. Four critical domains serve as the foundation for our guiding considerations: funding priorities, strategies to attract SETOCs, the role of educator preparation programs, and strategies to retain SETOCs.
Decoding Trans-Saccadic Prediction Error
Authors: Barne Louise Catheryne , Giordano Jonathan , Collins Thérèse , Desantis Andrea
Published: February 2023

We are constantly sampling our environment by moving our eyes, but our subjective experience of the world is stable and constant. Stimulus displacement during or shortly after a saccade often goes unnoticed, a phenomenon called the saccadic suppression of displacement. Although we fail to notice such displacements, our oculomotor system computes the prediction errors and adequately adjusts the gaze and future saccadic execution, a phenomenon known as saccadic adaptation. In the present study, we aimed to find a brain signature of the trans-saccadic prediction error that informs the motor system but not explicit perception. We asked participants (either sex) to report whether a visual target was displaced during a saccade while recording electroencephalography (EEG). Using multivariate pattern analysis, we were able to differentiate displacements from no displacements, even when participants failed to report the displacement. In other words, we found that trans-saccadic prediction error is represented in the EEG signal 100 ms after the displacement presentation, mainly in occipital and parieto-occipital channels, even in the absence of explicit perception of the displacement.

SIGNIFICANCE STATEMENTStability in vision occurs even while performing saccades. One suggested mechanism for this counterintuitive visual phenomenon is that external displacement is suppressed during the retinal remapping caused by a saccade. Here, we shed light on the mechanisms of trans-saccadic stability by showing that displacement information is not entirely suppressed and specifically present in the early stages of visual processing. Such a signal is relevant and computed for oculomotor adjustment despite being neglected for perception.
Deep Neural Networks and Visuo-Semantic Models Explain Complementary Components of Human Ventral-Stream Representational Dynamics
Authors: Jozwik Kamila M. , Kietzmann Tim C. , Cichy Radoslaw M. , Kriegeskorte Nikolaus , Mur Marieke
Published: February 2023

Deep neural networks (DNNs) are promising models of the cortical computations supporting human object recognition. However, despite their ability to explain a significant portion of variance in neural data, the agreement between models and brain representational dynamics is far from perfect. We address this issue by asking which representational features are currently unaccounted for in neural time series data, estimated for multiple areas of the ventral stream via source-reconstructed magnetoencephalography data acquired in human participants (nine females, six males) during object viewing. We focus on the ability of visuo-semantic models, consisting of human-generated labels of object features and categories, to explain variance beyond the explanatory power of DNNs alone. We report a gradual reversal in the relative importance of DNN versus visuo-semantic features as ventral-stream object representations unfold over space and time. Although lower-level visual areas are better explained by DNN features starting early in time (at 66 ms after stimulus onset), higher-level cortical dynamics are best accounted for by visuo-semantic features starting later in time (at 146 ms after stimulus onset). Among the visuo-semantic features, object parts and basic categories drive the advantage over DNNs. These results show that a significant component of the variance unexplained by DNNs in higher-level cortical dynamics is structured and can be explained by readily nameable aspects of the objects. We conclude that current DNNs fail to fully capture dynamic representations in higher-level human visual cortex and suggest a path toward more accurate models of ventral-stream computations.

SIGNIFICANCE STATEMENTWhen we view objects such as faces and cars in our visual environment, their neural representations dynamically unfold over time at a millisecond scale. These dynamics reflect the cortical computations that support fast and robust object recognition. DNNs have emerged as a promising framework for modeling these computations but cannot yet fully account for the neural dynamics. Using magnetoencephalography data acquired in human observers during object viewing, we show that readily nameable aspects of objects, such as 'eye', 'wheel', and 'face', can account for variance in the neural dynamics over and above DNNs. These findings suggest that DNNs and humans may in part rely on different object features for visual recognition and provide guidelines for model improvement.
Quantum chemical insight properties of glyphosine(N, N-Bis (phosphonomethyl) glycine) – a combined hf and density functional study
Authors:   Department of Science and Humanities, Sri Eshwar College of Engineering,Kinathukkadavu, Tamil Nadu 641202, India, Gokila A. , Ayyappan S. ,   Department of Physics, Government College of Technology, Coimbatore, Tamil Nadu 64101, India
Published: February 2023

The ab initio HF and Density Functional (DFT / B3LYP) method with a 6-31G(d, p) basis was used to declare a geometric structure and vibrational wave ranges of the glyphosine (GPS) (N, N-Bis (phosphonomethyl) glycine). HF and DFT calculations have optimized geometric hops. The B3LYP method, basis set on a 6-31 G (d, p), is the best level in theory for repeating constructive wave numbers.Density functional theory was used to explore the first hyperpolarizability (β) of the GPS. The results of the computations also indicate that the fragment GPS could be analyzed with Natural Bond Orbital (NBO). The FT-IR and FT-Raman theoretical spectra were constructed for the title component. The prospective, absolute and partial molecular electrostatic density (TDOS, PDOS) was evaluated for the GPS. The established energy from HOMO and LUMO shows that the charge is transferred in the fragment.
Inhibition potency of disulphides and trisulphides on various tumor cell lines growth
Authors:   University of Belgrade - Faculty of Chemistry, Studentski trg 12-16, 11000 Belgrade, Serbia, Mandić B. , Simić K. ,   Institute of Chemistry, Technology and Metallurgy, National Institute, University of Belgrade, Studentski trg 12-16, 11000 Belgrade, Serbia, Trifunović S. ,   University of Belgrade - Faculty of Chemistry, Studentski trg 12-16, 11000 Belgrade, Serbia, Vujisić Lj. ,   University of Belgrade - Faculty of Chemistry, Studentski trg 12-16, 11000 Belgrade, Serbia, Novaković M. ,   Institute of Chemistry, Technology and Metallurgy, National Institute, University of Belgrade, Studentski trg 12-16, 11000 Belgrade, Serbia, Tešević V. ,   University of Belgrade - Faculty of Chemistry, Studentski trg 12-16, 11000 Belgrade, Serbia, Miljanić O. Š. ,   Department of Chemistry, University of Houston, 112 Fleming Building, Houston TX 77204-5003, USA
Published: February 2023

Tumor is one of the leading diseases of today. Chemotherapy and radiation therapy healing chances are limited, so some alternative methods are resorted to. Many papers indicated that garlic and organosulphur compounds diallyldisulphide (DADS) and diallyltrisulphide, which are main components of garlic decrease the cancer risk and inhibit the cell proliferation. In this paper inhibition potency of disulphides (DADS and its synthetic analogues) and trisulphides with different alkyl and phenyl substituents on growth of various tumor (Non-Small cell Lung Cancer, Colon cancer, CNS Cancer, Melanoma, Ovarian Cancer, Renal Cancer, Prostate Cancer, Breast Cancer, Leukemia) cell lines was investigated. Concentration of each compound (DADS, diethyl disulphide, dipropyl disulphide, diphenyl disulphide, tetraethylthiuram disulphide (TETUDS), dimetil trisulphide, dipropyl trisulphide and metilpropyl trisulphide (MPTS) was 10 µmol/L. It was found that DADS has an inhibitory effect on the growth of several cancer cell lines, but synthetic analogues TETUDS and MPTS exhibit stronger effect on certain cells lines. MPTS inhibits the growth of even 12 cell lines for more than 10%, especially leukemia cell line SR and NCI-H522 cell line of Non-Small cell Lung Cancer (reduction of growth for 24% and 47%, resp.). Trisulphide analogues exhibit little higher inhibitory effects in comparison to disulphide ones.
Influence of surface microstructure parameters on wear of steel ball unfolding wheel
Authors:   Key Laboratory of Advanced Manufacturing and Intelligent Technology, Ministry of Education, China, Pan C. Y. , Chang J. H. ,   Key Laboratory of Advanced Manufacturing and Intelligent Technology, Ministry of Education, China, Cao G. Q. ,   Key Laboratory of Advanced Manufacturing and Intelligent Technology, Ministry of Education, China
Published: February 2023

The unfolding wheel is an important part of the steel ball tester in rolling bearing industry, and it is easy to be worn out. In this study, the pit microstructure is applied to the working surface of the unfolding wheel to reduce wear, improve its service life and reduce the testing cost of the steel ball. To analyze the influence of surface microstructure geometrical parameters on the abrasion of unfolding wheel under dry friction condition, the following research was conducted. First of all, the influence of shape, area, depth, and spacing of the microstructure pits on the abrasion of the specimen surface is studied by the orthogonal test method. Then, the subsurface stress of microstructure in contact with the steel ball is analyzed by ANSYS software. Comparing the simulated stress distribution with experimental wear mass, it is found that the more concentrated the high-stress area, the less wear. The diamond microstructure with a single pit area of 3.14×10-2 mm2 and a depth of 100 μm has the best abrasion reduction effect. Finally, the mathematical models including microstructure geometrical parameters for calculating the wear mass of microstructure surface are established. The mathematical models can be used to predict the life of steel ball unfolding wheel and assist the design.
Influence of rice starch nanocrystals on the film properties of the bionanocomposite edible films produced from native rice starch
Authors:   College of Water Resources Engineering , Al-Qasim Green University , Babylon, Iraq, Al-Aseebee M. D. F. , Rashid A.H. ,   Chemical Engineering Department , College of Engineering , University of AL Muthanna , Iraq, Naje A.S. ,   College of Water Resources Engineering , Al-Qasim Green University , Babylon, Iraq, Jayara J. J. ,   School of Mechanical Engineering, Sathyabama Institute of Science and Technology, Chennai, India, Maridurai T. ,   Department of Mechanical Engineering , Saveetha School of Engineering , SIMATS, Chennai.602105, India
Published: February 2023

In the present investigation, the bionanocomposite films were prepared by incorporating rice starch nanocrystals with rice starch based edible films through solution casting method. SNC were obtained from rice starch granules through acid hydrolysis followed by ultrasonication. Rice starch based edible films were prepared by incorporating the rice SNC at varying concentrations (0, 5, 10, 15, 20and25% of rice starch) through solution casting. The film properties, such as water vapour transmission rate (WVTR), mechanical properties, and film colour were determined. From the results, it was observed that the addition of rice SNC did not affect the film colour but significantly improved the mechanical strength and water resistance.
INVESTIGATION OF THE EFFECT OF ANNEALING TEMPERATURE ON STRUCTURAL, OPTICAL AND ANTIBACTERIAL PROPERTIES OF COPPER OXIDE NANOPARTICLES PREPARED BY FACILE CO-PRECIPITATION ROUTE
Authors:   Department of Physics, University of Agriculture, Faisalabad-38040 Pakistan, ANWAR H. ,   Department of Biochemistry, University of Agriculture, Faisalabad-38040  Pakistan, NAQVI S. M. B. , ABBAS B. , SHAHID M. , IQBAL M. , SHAHARYAR M. , ISLAM A. , BATOOL F. , KHALID M. , JAMIL A.
Published: February 2023

Copper oxide (CuO) nanoparticles are important due to their excellent properties and applications such as nano electronics, gas sensors, solar cell and super conductors. Copper oxide have been successfully prepared by using co-precipitation method. CuCl2. 2H2O and NaOH are used in the synthesis of copper oxide nanoparticles as a precursers. Samples annealed at different temperatures such as 400 ºC, 500 ºC, 600 ºC and 700 ºC. The as prepared samples were investigated X-ray diffraction (XRD), scanning electron microscopy (SEM), UV-vis spectroscopy. Their using Antibacterial activity against the two bacterial strain Gram-positive and Gram negative such as (E. coli and B. subtilis) and Hemolysis. Was also investigated XRD analysis showed structure of copper oxide nanoparticles was monoclinic and average crystallite size was found to increase with an increase in annealing temperature in the range of 35 nm to 45 nm. Morphology of SEM images showed that CuO nanostructures were rod like at lower temperature but in higher temperature sphere- like shape was observed. UV-visible spectroscopy results revealed the variation of band gap energy with increasing annealing temperature. Samples prepared at higher temperatures exhibited high antibacterial activity for E. coli and B. subtilis and low toxicity. Low homolytic is safer to use in different applications.
MECHANICAL, DEGRADATION AND MORPHOLOGICAL INVESTIGATIONS ON TAMARINDUS INDICA REINFROCED POLY LACTIC ACID BIO-COMPOSITE FOR BIOMEDICAL APPLICATIONS
Authors:   Department of Mechanical Engineering, Gnanamani College of Technology,  Namakkal,Tamilnadu, India - 637018, SACHIN S. R. , KUZMIN A. M. ,   Department of Mechanization of Agricultural Products Processing, Ogarev  Mordovia State University, Mordovia, Russia - 430005, THIRUVASAGAM C.
Published: February 2023

This research investigates the degradation and mechanical potential of Tamarindus Indiaca Fiber (TIF) reinforced into Poly Lactic Acid (PLA) resulting in a Wood Plastic Composite (WPC) that could be a potential alternative for prosthetic limbs. Fiber weight ratios at 10, 15, 20 and 25 wt%, were processed in micro and nano sizes individually through extrusion. Mechanical investigations were studied to analyze tensile, flexural, impact and hardness properties. Water Absorption Test (WAT) and Thermo Gravimetric Analysis (TGA) were performed for degradation studies. Field Emission Scanning Electron Microscope (FESEM) was used to study morphology. Nano TIF filled WPCs had superior properties than the micro TIF filled WPCs.
Ketabahan (Hardiness) dan Dukungan Sosial Ayah yang Memiliki Anak dengan Gangguan Spektrum Autisme
Authors: Prastuti Endang , Amrullah Novita Candra
Published: February 2023

Tujuan penelitian ini: (1) mengetahui hubungan dukungan sosial dan ketabahan (hardiness); (2) memberikan gambaran dukungan sosial ayah yang memiliki anak dengan gangguan spektrum autisme; dan (3) memberikan gambaran ketabahan (hardiness) pada ayah yang memiliki anak dengan gangguan spektrum autisme. Penelitian ini menggunakan studi populasi yaitu seluruh anggota populasi yang berjumlah 60 orang dijadikan subjek penelitian. Instrumen yang digunakan ialah skala dukungan sosial dan skala ketabahan (hardiness scale). Hasil penelitian menunjukkan bahwa terdapat hubungan positif dan signifikan dukungan sosial dan ketabahan pada ayah yang memiliki anak dengan gangguan spektrum autisme (Rxy = 0,824; P0,01).This study aims to (1) find out the correlation between social support and hardiness; (2) A description of the social support in the father who has children with autism spectrum disorder; and (3) A description of the hardiness in the father who has children with autism spectrum disorder. The study used population studies that amounted to 60 people as the subject of research. The instruments used are the social support and the hardiness scale. The results showed that there was a positive and significant between social support and a hardiness in a father who had children with autism spectrum disorder (rxy = 0,824; p0,01).
Peran Psychological Well-Being dan Efikasi Diri terhadap Stres pada Guru PAUD
Authors: Maharani Ega Asnatasia , Wati Dewi Eko
Published: February 2023

Survei di beberapa negara telah konsisten mencatat guru sebagai salah satu profesi dengan kerentanan stres tertinggi. Penelitian ini adalah penelitian dasar yang bertujuan menggali konstruk kesejahteraan psikologis (psychological well-being) dan efikasi diri sebagai nilai potensial yang nantinya dapat dikembangkan sebagai bagian intervensi penanganan stres pada guru. Partisipan penelitian adalah 116 guru Taman Kanak-kanak (TK) di Kabupaten Bantul Yogyakarta yang telah memiliki masa kerja minimal 2 tahun. Instrumen yang digunakan untuk pengambilan data adalah Perceived Stress Scale (PSS-10), Psychological Well-being Scale (PSWB), dan Teacher Sense Efficacy Scale (TSE). Ketiga skala tersebut disebarluaskan secara online ke Kecamatan Banguntapan dan Sewon sebagai cluster sampling. Data yang terkumpul dianalisis menggunakan regresi linier berganda. Hasil penelitian menunjukkan bahwa ada pengaruh signifikan antara psychological well-being dan efikasi diri terhadap tingkat stres guru. Sumbangan efektif terhadap stres guru yang dijelaskan oleh kedua variabel bebas sebesar 42.9% (p .001). Studi ini menyimpulkan bahwa psychological well-being dan efikasi diri dapat dikembangkan sebagai konstruk intervensi untuk peningkatan kesehatan mental guru.Surveys in several countries have consistently listed teachers as one of the professions with the highest stress vulnerability. This research is basic research that explores psychological well-being and self-efficacy as potential values that can later be developed as part of the stress management intervention for teachers. The data were collected through an online survey from 116 Kindergarten teachers who had minimum 2 years of working experience. Banguntapan and Sewon districts were chosen as cluster sampling from Bantul Regency, Yogyakarta. The instruments used for data collection were the Perceived Stress Scale (PSS-10), the Psychological Well-being Scale (PSWB), and the Teacher Sense Efficacy Scale (TSE). Descriptive statistics and a multiple linear regression test were employed. Results showed that psychological well-being and self-efficacy jointly affected teachers' stress levels by 42.9% (p .001). This study concludes that psychological well-being and self-efficacy have a significant adverse effect on stress. It can be developed as an intervention construct to improve the teacher's mental health.
Analisis Dampak Penggunaan Video Conference Terhadap Kemunculan Zoom Fatigue pada Mahasiswa
Authors: Salma Salma , Machfudh M Sahal , Salwa Arvica , Firdaus Alphindo Muhammad
Published: February 2023

Pandemi COVID-19 yang menyerang hampir seluruh belahan dunia memunculkan dampak terhadap berbagai aspek kehidupan, termasuk pendidikan. Proses pembelajaran yang awalnya berlangsung secara tatap muka beralih menjadi daring. Salah satu media pembelajaran daring yang banyak digunakan adalah video conference. Akan tetapi, penggunaan video conference memunculkan fenomena baru bagi penggunanya, yaitu zoom fatigue atau kelelahan akibat penggunaan video conference. Meski telah cukup banyak diulas, fenomena zoom fatigue masih belum banyak dikaji secara ilmiah. Tujuan penelitian ini adalah untuk mengeksplorasi dampak dan penyebab zoom fatigue pada mahasiswa salah satu perguruan tinggi negeri di Semarang, Jawa Tengah. Penelitian ini menggunakan metode kualitatif studi kasus. Pengambilan data menggunakan metode wawancara, observasi, dan dokumen pendukung. Partisipan yang terlibat adalah lima orang mahasiswa, lima orang anggota keluarga mahasiswa, dan dua orang dosen. Hasil penelitian ini menemukan dampak zoom fatigue berupa dampak fisiologis, psikologis, perilaku, hubungan dengan orang sekitar dan tanda-tanda kemunculan zoom fatigue. Faktor-faktor penyebab zoom fatigue terdiri atas, faktor internal dan faktor eksternal, kendala, serta hambatan penggunaan video conference.The COVID-19 pandemic has spread worldwide and affected many life aspects. One of the aspects that have been affected significantly by the pandemic is education. Offline educational systems need to adapt to the situation by shifting to online educational systems. Video conferences have gained popularity as one of the methods schools can use to conduct online classes. However, the rise of video conferences has brought out a new problem to solve, i.e., the zoom fatigue phenomenon. Zoom fatigue is a condition characterized by fatigue from video conferences. Despite the trending discussion about Zoom fatigue, the scientific study is still limited. This study aims to explore the impacts and causes of zoom fatigue among university students in Semarang, Central Java. This study is a qualitative study with a case study approach. Data were collected through interviews, observation, and complimentary document artifacts. Participants comprised five university students, five family members, and two lecturers. This study finds that the impacts of zoom fatigue consist of physical, physiological, behavioral, interpersonal connection, and zoom fatigue symptoms. Meanwhile, the cause factors include internal and external factors, obstacles, and hindrances.
TAHKİM SÖZLEŞMESİNİN VARLIĞI DURUMUNDA DAVA ŞARTI ARABULUCULUK HÜKÜMLERİNİN UYGULANIP UYGULANAMAYACAĞI ÜZERİNE DEĞERLENDİRMELER (HUAK m. 18/A,18)
Authors: BÖRÜ Levent
Published: February 2023

Son zamanlarda dava şartı (zorunlu) arabuluculuk uygulamasının gelişmesi ile birlikte, tahkime ve arabuluculuğa ilişkin mevzuat hükümlerinin uygulanması noktasında sorunlar ortaya çıkmıştır. Özellikle aynı somut olayda tahkime ve arabuluculuğa ilişkin HUAK, HMK ve özel kanunlarda dava şartına ilişkin (TTK m. 5/A; İK m. 3; TKHK m. 73/A) hükümlerin hangilerinin öncelikle uygulanması gerektiği cevaplandırılması gereken bir sorun olarak ortaya çıkmıştır. Söz konusu sorunun çözümü HUAK m. 18/A,18 hükmü ile düzenlenmiş olmasına rağmen, hükmün yorumlanması bakımından uygulamada bazı tartışmaların yaşandığı görülmektedir. Çalışmamız, HUAK m. 18/A,18 hükmünün değerlendirilmesi üzerinedir. Başka bir deyişle tahkim sözleşmesi karşısında, dava şartı arabuluculuk hükümlerinin HUAK m. 18/A,18 karşısında nasıl bir uygulamasının olması gerektiğinin değerlendirilmesi yapılmıştır.
Effect of dry heat and polishing treatment on the germination rate and performance of seeds from Cassia obtusifolia L. as a turf filling material
Authors: Wang Luyang , Zhang Weixing , Chai Xicun , Zhou Yu , He Chunxia
Published: February 2023

Seeds from Cassia obtusifolia L., i.e. Semen cassiae (SC) were evaluated as environmentally friendly filler particles for artificial turf. The goal was to avoid unwanted germination problems of SC under wet conditions. This work evaluated the influence of different pretreatments on the germination rate and performance of SC. After the combination of polishing and dry heat (90 °C, 72 h) treatment, the germination rate of SC decreased to 0% and the activation energy increased to 216 kJ/mol. Compared with the untreated SC, the thermal stability of SC improved, with an initial degradation temperature of 214 °C and a pyrolysis residue of 31.9%. Additionally, the resilience and the water absorption of SC as a filler material increased to 4.13% and 169%, respectively. This study provides an effective pretreatment method for the solution of germination problem and the performance improvement of SC. This makes the pretreated SC a prospective candidate as an environmentally protective granular filling material.
Visual Code of Realism in Ivan Nechuy-Levytskyi
Authors:   Taras Shevchenko Institute of Literature, National Academy of Sciences of Ukraine, Muravetska/ Yaroslava
Published: February 2023

Yaroslava Muravetska, for the first time in Ukrainian literary studies, explores visual imagery in the fiction of I. Nechuy-Levytskyi. Also, using the example of his work, the researcher analyzes the poetics of realism in terms of the visual code. The researcher outlines functioning of the «visuality» notion in modern literary science, develops the concept of realism at a literary and critical works of I. Nechui-Levytskyi. The role of visual strategies in the writer’s prose is emphasized and the place of visuality in his writing style is determined, as well as the creativity through the prism of visual imagery is considered. There have been characterized the peculiarities of portraying and landscape description and identified the intermedial forms of theatricalization and painterliness in I. Nechui-Levytskyi’s prose. The focus is made on visual representation of literary styles, in particular decadence, within the writer’s creativity, modern intermedial interpretations of I. Nechui-Levytskyi’s novel “Kaidasheva simia” (“Kaidash’s Family”) have been analyzed in the context of visuality. Yaroslava Muravetska applies the methodology of visual studies for the analysis of literature and demonstrates that literature can be an object for visual studies (1.1). The researcher clarifies the individual features of Ivan Nechuy-Levytskyi’s style at the theoretical (1.2, 2.2.) and practical levels (sections 2, 3), and also analyses the presence of romantic, folkloric (1.2, 3.3.) and pre-impressionist (3.4.) features in the author’s style. The author proves that the use of visuality in the writer’s prose is not limited to ethnography and everyday reality, but, in particular, serves to indirectly express the idea of ​​the work (chapters 2, 3). The scientist gives attention to the use of visuality as a storytelling element (chapter 2), and studies the intermedial aspects of the interaction of visuality and literature (chapter 3.1, 3.2, 4). In particular, the scientist highlights the influence of theatrical (3.1) and pictorial (3.2) art on the stylistic, thematic, storytelling level of Ivan Nechuy-Levytskyi’s prose. Finally, the researcher analyzes the impact of the writer’s story “The Kaidash Family” on more recent works by other authors, using the example of book illustrations, a film-diptych, and a play. The author focuses on the art of “translation” from “verbal” to “visual” language (chapter 4).