bluuebunny/crossref_metadata_2025 huggingface dataset:
Management of Cervical Spinal Cord Injury without Major Bone Injury in Adults
Authors: Nakajima Hideaki , Honjoh Kazuya , Watanabe Shuji , Takahashi Ai , Kubota Arisa , Matsumine Akihiko
Published: October 2023

The incidence of cervical spinal cord injury (CSCI) without major bone injury is increasing, possibly because older people typically have pre-existing cervical spinal canal stenosis. The demographics, neurological injury, treatment, and prognosis of this type of CSCI differ from those of CSCI with bone or central cord injury. Spine surgeons worldwide are debating on the optimal management of CSCI without major bone injury. Therefore, this narrative review aimed to address unresolved clinical questions related to CSCI without major bone injury and discuss treatment strategies based on current findings. The greatest divide among spine surgeons worldwide hinges on whether surgery is necessary for patients with CSCI without major bone injury. Certain studies have recommended early surgery within 24 h after injury; however, evidence regarding its superiority over conservative treatment remains limited. Delayed MRI may be beneficial; nevertheless, reliable factors and imaging findings that predict functional prognosis during the acute phase and ascertain the necessity of surgery should be identified to determine whether surgery/early surgery is better than conservative therapy/delayed surgery. Quality-of-life assessments, including neuropathic pain, spasticity, manual dexterity, and motor function, should be performed to examine the superiority of surgery/early surgery to conservative therapy/delayed surgery.
Current Role of SLGT2 Inhibitors in the Management of the Whole Spectrum of Heart Failure: Focus on Dapagliflozin
Authors: Escobar Carlos , Pascual-Figal Domingo , Manzano Luis , Nuñez Julio , Camafort Miguel
Published: October 2023

Heart failure (HF) is associated with a high morbidity and mortality burden. In light of more recent evidence, SGLT2 inhibitors are currently recommended as first-line therapy in managing patients with HF, regardless of ejection fraction, to reduce HF burden. The DAPA-HF and DELIVER trials, and particularly, the pooled analysis of both studies, have shown that dapagliflozin significantly reduces the risk of cardiovascular death, all-cause death, total HF hospitalizations, and MACE in the whole spectrum of HF, with sustained benefits over time. Recent data have shown that the full implementation of dapagliflozin in clinical practice would translate into a robust reduction in hospitalizations for HF and death in real-life populations. Many pathophysiological mechanisms have been involved in these benefits, particularly the positive effects of dapagliflozin on reversing cardiac (atrial and ventricular) remodeling, reducing cardiac fibrosis and inflammation, and improving endothelial dysfunction. In this manuscript, we reviewed from a practical point of view the role of dapagliflozin in the management of the whole spectrum of patients with HF.
Elevated Sperm DNA Damage in IVF–ICSI Treatments Is Not Related to Pregnancy Complications and Adverse Neonatal Outcomes
Authors: Hervás Irene , Rivera-Egea Rocio , Pacheco Alberto , Gil Julia Maria , Navarro-Gomezlechon Ana , Mossetti Laura , Garrido Nicolás
Published: October 2023

This multicenter retrospective cohort study assesses the effect of high paternal DNA fragmentation on the well-being of the woman during pregnancy and the health of the newborn delivered. It was performed with clinical data from 488 couples who had a delivery of at least one newborn between January 2000 and March 2019 (243 used autologous oocytes and 245 utilized donated oocytes). Couples were categorized according to sperm DNA fragmentation (SDF) level as ≤15% or >15%, measured by TUNEL assay. Pregnancy, delivery, and neonatal outcomes were assessed. In singleton pregnancies from autologous cycles, a higher but non-significant incidence of pre-eclampsia, threatened preterm labor, and premature rupture of membranes was found in pregnant women from the >15%SDF group. Additionally, a higher proportion of children were born with low birth weight, although the difference was not statistically significant. After adjusting for potential confounders, these couples had lower odds of having a female neonate (AOR = 0.35 (0.1–0.9), p = 0.04). Regarding couples using donor’s oocytes, pregnancy and neonatal outcomes were comparable between groups, although the incidence of induced vaginal labor was significantly higher in the >15% SDF group (OR = 7.4 (1.2–46.7), p = 0.02). Adjusted analysis revealed no significant association of elevated SDF with adverse events. In multiple deliveries from cycles using both types of oocytes, the obstetric and neonatal outcomes were found to be similar between groups. In conclusion, the presence of an elevated SDF does not contribute to the occurrence of clinically relevant adverse maternal events during pregnancies, nor does it increase the risk of worse neonatal outcomes in newborns. Nevertheless, a higher SDF seems to be related to a higher ratio of male livebirths.
Therapeutic Potential of Rituximab in Managing Hepatitis C-Associated Cryoglobulinemic Vasculitis: A Systematic Review
Authors: Covic Andreea , Caruntu Irina Draga , Burlacu Alexandru , Giusca Simona Eliza , Covic Adrian , Stefan Anca Elena , Brinza Crischentian , Ismail Gener
Published: October 2023

(1) Background. Hepatitis C infection often leads to extrahepatic manifestations, including cryoglobulinemic vasculitis. This systematic review aimed to assess the efficacy and safety of rituximab in treating hepatitis C-associated cryoglobulinemic vasculitis. (2) Methods. Following PRISMA guidelines, databases were searched for relevant studies. Eligibility criteria included studies on hepatitis C-associated cryoglobulinemic vasculitis treated with rituximab. (3) Results. Nine studies met the eligibility criteria and were included in this analysis. Rituximab was commonly administered at 375 mg/m2 weekly for one month. The results consistently demonstrated the efficacy of rituximab, whether as a standalone treatment or as part of a therapeutic regimen. The combination of rituximab with Peg-IFN-α and ribavirin significantly increased the complete response rate compared to Peg-IFN-α and ribavirin alone (54.5% vs. 33.3%, p < 0.05). The 3-year sustained response rate was notably higher in the rituximab combination group (83.3% vs. 40%). In another trial, rituximab achieved remission in 83.3% of patients at 6 months, compared to only 8.3% in the control group. The efficacy of rituximab was supported by long-term experience, with clinical benefits in patients with severe cryoglobulinemic vasculitis, including those resistant to standard therapies. Mild adverse events were generally reported, with rare severe reactions in some studies. (4) Conclusions: In conclusion, rituximab appeared to be effective and safe in managing hepatitis C-associated cryoglobulinemic vasculitis, either alone or with antiviral therapy.
Evidence-Based Surgery: What Can Intra-Operative Images Contribute?
Authors: Regazzoni Pietro , Jupiter Jesse B. , Liu Wen-Chih , Fernández dell’Oca Alberto A.
Published: October 2023

Evidence-based medicine integrates results from randomized controlled trials (RCTs) and meta-analyses, combining the best external evidence with individual clinical expertise and patients’ preferences. However, RCTs of surgery differ from those of medicine in that surgical performance is often assumed to be consistent. Yet, evaluating whether each surgery is performed to the same standard is quite challenging. As a primary issue, the novelty of this review is to emphasize—with a focus on orthopedic trauma—the advantage of having complete intra-operative image documentation, allowing the direct evaluation of the quality of the intra-operative technical performance. The absence of complete intra-operative image documentation leads to the inhomogeneity of case series, yielding inconsistent results due to the impossibility of a secondary analysis. Thus, comparisons and the reproduction of studies are difficult. Access to complete intra-operative image data in surgical RCTs allows not only secondary analysis but also comparisons with similar cases. Such complete data can be included in electronic papers. Offering these data to peers—in an accessible link—when presenting papers facilitates the selection process and improves publications for readers. Additionally, having access to the full set of image data for all presented cases serves as a rich resource for learning. It enables the reader to sift through the information and pinpoint the details that are most relevant to their individual needs, allowing them to potentially incorporate this knowledge into daily practice. A broad use of the concept of complete intra-operative image documentation is pivotal for bridging the gap between clinical research findings and real-world applications. Enhancing the quality of surgical RCTs would facilitate the equalization of evidence acquisition in both internal medicine and surgery. Joint effort by surgeons, scientific societies, publishers, and healthcare authorities is needed to support the ideas, implement economic requirements, and overcome the mental obstacles to its realization.
Congenital, Acquired, and Trauma-Related Risk Factors for Thoracic Outlet Syndrome—Review of the Literature
Authors: Maślanka Krystian , Zielinska Nicol , Karauda Piotr , Balcerzak Adrian , Georgiev Georgi , Borowski Andrzej , Drobniewski Marek , Olewnik Łukasz
Published: October 2023

Thoracic outlet syndrome is a group of disorders that affect the upper extremity and neck, resulting in compression of the neurovascular bundle that exits the thoracic outlet. Depending on the type of compressed structure, the arterial, venous, and neurogenic forms of TOS are distinguished. In some populations, e.g., in certain groups of athletes, some sources report incidence rates as high as about 80 cases per 1000 people, while in the general population, it is equal to 2–4 per 1000. Although the pathogenesis of this condition appears relatively simple, there are a very large number of overlapping risk factors that drive such a high incidence in certain risk groups. Undoubtedly, a thorough knowledge of them and their etiology is essential to estimate the risk of TOS or make a quick and accurate diagnosis.
Corticophobia among Parents of Children with Atopic Dermatitis: Assessing Major and Minor Risk Factors for High TOPICOP Scores
Authors: Herzum Astrid , Occella Corrado , Gariazzo Lodovica , Pastorino Carlotta , Viglizzo Gianmaria
Published: October 2023

Corticophobia, fear of applying topical corticosteroids (TCSs), is a rising issue in industrialized countries, despite the actual safety of TCSs for atopic dermatitis (AD). Patients attending the Pediatric Dermatology Unit for skin examination were screened for AD. AD patients were included, and data were collected. Parental corticophobia was evaluated through the Topical Corticosteroid Phobia (TOPICOP) questionnaire. The χ2 test and logistic regression were used to analyze statistical associations between parental corticophobia (mild/moderate vs. severe) and patients’ and parents’ characteristics. Overall, 100 patients were included (53 females; 47 males; mean age 5.9 years): 44 had mild/moderate AD (EASI ≤ 21), and 56 had severe AD (EASI > 21) (mean EASI 19.7). Of the patients, 33 never consulted healthcare providers for AD, and 67 did. Parental education was low/intermediate in 60 cases and high (gymnasium/university degree) in 40. Mean parental DLQI was 10.7. Mean parental TOPICOP was 39.1%: 51 had mild/moderate corticophobia (TOPICOP ≤ 50%), and 49 had severe corticophobia (TOPICOP > 50%). At the χ2 test, corticophobia was associated with mild/moderate AD (OR 20.9487; 95% CI 7.2489–60.5402; p < 0.001), older age of patients (OR 4.1176; 95% CI 1.7880 to 9.4828; p < 0.001), early disease onset (OR 9.8925; 95% CI 2.7064–36.1596; p < 0.001), and previous healthcare professional consultations (OR 4.9279; 95% CI 1.9335–12.5597; p < 0.001). Also, severe parental corticophobia was very significantly associated with severe parental involvement of life quality (OR 33.3333; 95% CI 10.9046–101.8937; p < 0.001) and with high education of parents (gymnasium or university degree) (29/49) (OR 5.2727; 95% CI 2.1927–12.6790; p < 0.001). At logistic regression, high parental DLQI (p < 0.0001), high parental education (p < 0.0338), older age of patients (p = 0.0015), and early disease onset (p < 0.0513) accounted for major risk factors influencing severe parental corticophobia. Assessing risk factors for corticophobia is essential for addressing groups of parents at higher risk for corticophobia using educational programs, to overcome unfounded fears and augment treatment adherence.
Characterization and Modelling of Composites, Volume III
Authors: Georgantzinos Stelios K.
Published: October 2023

The realm of composite materials continues to evolve, with researchers pushing the boundaries of understanding and application. This Special Issue published in the Journal of Composites Science encapsulates the essence of these advancements, presenting a curated collection of research articles that highlight the latest developments in the characterization and modelling of composites. The diversity of the covered topics ranges from a foundational understanding of composite behaviours to the application of cutting-edge modelling techniques. Each contribution offers a fresh perspective, expanding our knowledge of composites and setting the stage for future explorations in this dynamic domain.
A Numerical Study of the Hydrodynamic Noise of Podded Propulsors Based on Proper Orthogonal Decomposition
Authors: Chen Changsheng , Li Guoping , Ma Zhenlai , Mei Ziyi , Gao Bo , Zhang Ning
Published: October 2023

Podded propulsors have become a focal point of research in the field of marine propulsion in recent years due to their high efficiency, low noise, and excellent maneuverability. To investigate the acoustic characteristics induced by the flow field of podded propulsors, a high-precision unsteady numerical simulation was conducted using the Delayed Detached Eddy Simulation (DDES) coupled with Ffowcs Williams–Hawkings (FW-H) equations. Multiple spatial acoustic receiving arrays were employed, and analysis methods including Proper Orthogonal Decomposition (POD) and Fast Fourier Transform (FFT) were utilized to determine the spatial distribution of the acoustic field of the podded propulsor. The results show that the blade passing frequency and the shaft frequency consistently dominate as the primary characteristic frequencies. On the plane of the propeller disk, the distribution of sound pressure levels is uniform without distinct directivity. Across the space curved surface, approximately the first ten POD modes encompass 99.8% of the total energy, and their spatial distribution characteristics of sound pressure are closely related to the pod structure. Additionally, these modes exhibit characteristic frequencies such as the blade passing frequency and shaft frequency. The spatial distribution of sound pressure at a single frequency on the spatial surface corresponds well with the results obtained from the POD analysis.
Assessment of Ship Hull Ultimate Strength under Fire Conditions: The Fire Smith Method Approach
Authors: Wu Jiaxin , Du ZhiPeng , Yan Ming , Sun Xingwei
Published: October 2023

This article presents the fire Smith method, which integrates the plate model and the Smith method, to analyze the impact of fire temperature and extent on the buckling strength of frigates. This investigation focused on the frigate’s buckling strength and how it is affected by a fire, achieved by modifying both deck temperature and area. Leveraging the principle of oxygen consumption, a coefficient “D” was introduced to account for fire temperature and region variations. This enabled the characterization of buckling strength under varying temperature and regional conditions through 64 simulations conducted on a frigate model. The outcomes revealed that the disparity between simulation results and the fire Smith method remained below 10%, establishing a solid basis for engineering assessment. As the high-temperature area decreased and necessitated less oxygen, the ultimate strength initiated a decline. However, upon reaching a certain threshold temperature, the ultimate strength stabilized. Conversely, expansive high-temperature zones caused a decline in ultimate strength, coupled with an increased oxygen requirement. Under consistent oxygen consumption conditions, the rate of ultimate strength reduction intensified. Consequently, these divergent characteristics of ultimate strength in various high-temperature areas underscored that minimizing the expansive fire high-temperature zones can significantly enhance the ship’s fire resistance, safeguarding its structural integrity.
Sporothrix brasiliensis Infection Modulates Antimicrobial Peptides and Stress Management Gene Expression in the Invertebrate Biomodel Galleria mellonella
Authors: Reis Nathália Faria , de Jesus Myrela Conceição Santos , de Souza Lais Cavalcanti dos Santos Velasco , Alcântara Lucas Martins , Rodrigues Julia Andrade de Castro , Brito Simone Cristina Pereira , Penna Patrícia de Azambuja , Vieira Cecília Stahl , Silva José Rodrigo Santos , Penna Bruno de Araújo , Machado Ricardo Luiz Dantas , Mora-Montes Hector M. , Baptista Andréa Regina de Souza
Published: October 2023

Sporothrix brasiliensis is the most pathogenic species, responsible for the Brazilian cat-transmitted sporotrichosis hyperendemic. In this scenario, an investigation of the pathogen–host interaction can provide relevant information for future treatment strategies. To this end, the invertebrate Galleria mellonella has proven to be a suitable alternative for evaluating the virulence of pathogenic fungi, since the insect immune system is similar to the mammalian innate immune response. The aim of this work was to investigate phenotypic and molecular aspects of the immune response of G. mellonella throughout the S. brasiliensis infection. Hemocyte density and the evolution of the fungal load were evaluated. In parallel, RT-qPCR expression analysis of genes encoding antimicrobial peptides (Gallerimycin and Galiomycin) and stress management genes (C7 Contig 15362 and C8 Contig 19101) was conducted. The fungal load and hemocyte densities increased simultaneously and proportionally to the deleterious morphological events and larvae mortality. Gallerimycin, C7 Contig 15362 and C8 Contig 19101 genes were positively regulated (p < 0.05) at distinct moments of S. brasiliensis infection, characterizing a time-dependent and alternately modulated profile. Galiomycin gene expression remained unchanged. Our results contribute to the future proposal of potential alternative pathways for treating and consequently controlling S. brasiliensis zoonosis, a major public health issue in Latin America.
Pyricularia’s Capability of Infecting Different Grasses in Two Regions of Mexico
Authors: Sequera-Grappin Ivan , Ventura-Zapata Elsa , De la Cruz-Arguijo Erika Alicia , Larralde-Corona Claudia Patricia , Narváez-Zapata Jose Alberto
Published: October 2023

The genus Pyricularia includes species that are phytopathogenic fungi, which infect different species of Poaceae, such as rice and sorghum. However, few isolates have been genetically characterized in North America. The current study addresses this lack of information by characterizing an additional 57 strains of three grasses (Stenotaphrum secundatum, Cenchrus ciliaris and Digitaria ciliaris) from two distant regions of Mexico. A Pyricularia dataset with ITS sequences retrieved from GenBank and the studied sequences were used to build a haplotype network that allowed us to identify a few redundant haplotypes highly related to P. oryzae species. An analysis considering only the Mexican sequences allowed us to identify non-redundant haplotypes in the isolates of C. ciliaris and D. ciliaris, with a high identity with P. pennisetigena. The Pot2-TIR genomic fingerprinting technique resulted in high variability and allowed for the isolates to be grouped according to their host grass, whilst the ERIC-PCR technique was able to separate the isolates according to their host grass and their region of collection. Representative isolates from different host grasses were chosen to explore the pathogenic potential of these isolates. The selected isolates showed a differential pathogenic profile. Cross-infection with representative isolates from S. secundatum and C. ciliaris showed that these were unable to infect D. ciliaris grass and that the DY1 isolate from D. ciliaris was only able to infect its host grass. The results support the identification of pathogenic strains of Pyricularia isolates and their cross-infection potential in different grasses surrounding important crops in Mexico.
20-Year Ecological Impact Analysis of Shibing Karst World Natural Heritage through Land Use
Authors: Zhang Ning , Chi Yongkuan
Published: October 2023

Changes in the spatial pattern of land use are inextricably linked to the ecosystem environment, and the assessment of regional eco-environment quality can help provide sustainable and healthy development strategies for heritage management organizations. In this study, based on RS and GIS technologies, we quantitatively analyzed the characteristics of land use changes in the Shibing Karst World Natural Heritage site from 2000 to 2020, and introduced the regional eco-environment quality assessment index for quantitative factor analysis. The results show that: (1) The heritage site is mainly dominated by forest and shrub, with more aggregated cropland, and impervious surfaces in the buffer zone. The area of shrub has increased during the 20-year period, occupying 12.63% of the total transferred area. Cropland has been basically converted to forest, accounting for more than 60% of the total transferred area, followed by shrubs, which have been basically transferred to ecologically better land types. (2) By analyzing the attitude of motivation, forest, shrub, and water have positive values, while cropland, grassland, and impervious surfaces have negative values. Grassland has the largest absolute value of kinetic attitude, and the smallest is for water. The integrated dynamic attitude is basically maintained at 24%, showing a state of rapid and then stable land category conversion. (3) Over the past 20 years, the regional eco-environment quality index has been stable between 0.68 and 0.71, and shows a trend of rapid growth and stabilization, which is consistent with the comprehensive attitude. The conversion between cropland, forest, and shrubs is the main cause of ecological improvement and deterioration. Overall, the relevant conservation measures at the site and China’s corresponding responses to global climate change have led to a stabilization and increase in the regional ecological quality of the site. The management measures of the relevant authorities have begun to bear fruit, but further promotion of the sustainable development of the site is needed to provide a scientific model for the conservation of other karst heritage sites.
Movement Asymmetries: From Their Molecular Origin to the Analysis of Movement Asymmetries in Athletes
Authors: Egoyan Alexander , Parulava Giorgi , Baker Steven , Gilhen-Baker Melinda , Roviello Giovanni N.
Published: October 2023

Asymmetry plays a major role in biology at all scales. This can be seen in the helix of DNA, the fact that the human heart is on the left side, or that most people use their right hand. A single protein such as Myosin 1D can induce helical motion in another molecule. This causes cells, organs, and even entire bodies to twist in a domino effect, causing left–right behaviour. More generally, athlete movements are often asymmetric and, during the physical rehabilitation after injury, the asymmetry is visually discernible. Herein, we review the molecular basis of the movement asymmetries and report on the available knowledge on the few therapeutics investigated so far such as meloxicam. From a more rehabilitative perspective, it is very important to use effective methods to control the process of resolving the injury-related movement asymmetry through the complex use of specialised exercises, measurements, and gait analysis, which can all provide useful information on the effectiveness of the rehabilitation plans. If for each athlete, the normal range of asymmetry is known, the asymmetry can be individually treated and the evolution can be monitored over time. Appropriate measures should be taken if the movement asymmetry is outside this range. In addition, genetic, physiological, and psychological factors relevant to athlete health should be considered in the process of assessing and improving exercise asymmetry, which we also discuss in this review. The main proposal of this work is that the movement asymmetries in athletes should be individually treated, while taking into account the athlete’s genetics, physical condition, and previous injuries.
Impact of Immunity on Coronary Artery Disease: An Updated Pathogenic Interplay and Potential Therapeutic Strategies
Authors: Laera Nicola , Malerba Paolo , Vacanti Gaetano , Nardin Simone , Pagnesi Matteo , Nardin Matteo
Published: October 2023

Coronary artery disease (CAD) is the leading cause of death worldwide. It is a result of the buildup of atherosclerosis within the coronary arteries. The role of the immune system in CAD is complex and multifaceted. The immune system responds to damage or injury to the arterial walls by initiating an inflammatory response. However, this inflammatory response can become chronic and lead to plaque formation. Neutrophiles, macrophages, B lymphocytes, T lymphocytes, and NKT cells play a key role in immunity response, both with proatherogenic and antiatherogenic signaling pathways. Recent findings provide new roles and activities referring to endothelial cells and vascular smooth muscle cells, which help to clarify the intricate signaling crosstalk between the involved actors. Research is ongoing to explore immunomodulatory therapies that target the immune system to reduce inflammation and its contribution to atherosclerosis. This review aims to summarize the pathogenic interplay between immunity and CAD and the potential therapeutic strategies, and explore immunomodulatory therapies that target the immune system to reduce inflammation and its contribution to atherosclerosis.
Effect of the Type of Lateritic Soil on the Effectiveness of Geomechanical Improvement Using a Low Quantity of Cement for Sustainable Road Construction
Authors: Mbengue Marie Thérèse Marame , Lawane Gana Abdou , Messan Adamah , Mone Ousseni , Pantet Anne
Published: October 2023

In Burkina Faso, the most commonly used road construction material is lateritic soil. However, in its raw state, this soil does not meet the required recommendations. To overcome this problem, previous studies have often focused on improving these soils by adding cement. However, these studies have rarely included a multi-criteria characterisation of the main geomechanical parameters of treated soils. It was also noted that the identification parameters of lateritic soils could have an influence on their improvement with cement. The aim of this study is to highlight the influence of the physical and mineralogical properties of lateritic soils on the effectiveness of improving their geomechanical properties by adding a low content of cement (<3% wt.). The soils were taken from two sites: Saaba (LAS) and Kamboinsé (LAK). The effects of cement addition on the plasticity index, CBR index, Young’s modulus, unconfined compressive strength, tensile strength and shear strength were studied. In their raw state, LAS and LAK have different physical properties and cannot be used as sub-bases. The addition of cement improves the overall physical and mechanical properties of both soils, but to different degrees. Indeed, after adding 3% cement to the raw soils, the CBR index of LAS increases by 1275% compared with 257% for LAK; the unconfined compressive strength of LAS is twice as high as that of LAK, and the Young’s modulus increases by around 460% for LAS compared with 360% for LAK. After improvement, these two soils met all the CEBTP specifications except for tensile strength. The effect of cement was more significant on LAS due to its better physical properties and higher clay mineral content, which would improve pozzolanic reactivity during cement hydration. Knowing the mineralogy of lateritic soils when treating them with cement would allow us to reduce the quantity of cement, thereby mitigating its negative impact on the environment.
Calibration of Yld2000-2D Anisotropy Yield Criterion with Traditional Testing and Inverse Identification Strategies
Authors: Chen Jiaqi , Wang Zhihao , Chu Xingrong , Yue Zhenming , Zhao Chao , Zhou Yiqi
Published: October 2023

In order to improve predictive capabilities of numerical simulations, Yld2000-2D yield criterion is used to model the plastic anisotropic behaviors of AA5086 sheets. The parameters of Yld2000-2D yield criterion are identified based on the traditional testing strategy and the inverse identification strategy, respectively. The traditional testing strategy considers uniaxial and equi-biaxial tensile tests. The inverse identification strategy relies on the finite element model update (FEMU) method that couples with a biaxial tensile test using a dedicated cruciform specimen or the Pottier bulging test. The identified parameters are preliminarily evaluated by comparing predicted and experimental yield stresses, r-values, and yield loci. Then, the deep drawing test and simulations are performed. The identified parameter sets of Yld2000-2D yield criterion are further evaluated in terms of practical forming by comparing the predicted earing profile height with the experimental results. The results show that the inverse identification strategy can be an effective alternative to identify the parameters of Yld2000-2D yield criterion, and a well-designed heterogeneous test could lead to a better identification result.
Analyzing the Effects of Nano-Titanium Dioxide and Nano-Zinc Oxide Nanoparticles on the Mechanical and Durability Properties of Self-Cleaning Concrete
Authors: Mostafa Fatma El-Zahraa M. , Smarzewski Piotr , El Hafez Ghada M. Abd , Farghali Ahmed A. , Morsi Wafaa M. , Faried Ahmed S. , Tawfik Taher A.
Published: October 2023

The goal of this paper is to investigate the impact of nano-materials on the mechanical and electrochemical properties of self-cleaning concrete. Nano-titanium dioxide and nano-zinc oxide were used as additives for this purpose. Additionally, a comparative study on the effect of using these materials on the self-cleaning concrete’s characteristics was conducted. The dosages of nano-titanium dioxide (nps-TiO2) and nano-zinc oxide (nps-ZnO) used were 0, 0.5, 1, 1.5, 2, and 2.5% and 0, 1, 2, and 3% of the weight of the cement, respectively. The results showed that the optimum compressive strength and the lowest corrosion rate were fulfilled at 2.5% of nps-TiO2 and 1% of nps-ZnO, and using 2.5% of nps-TiO2 achieved the highest improvement in the corrosion rate. However, 1% for nps-TiO2 mixtures and 1% for nps-ZnO mixtures were the best ratios for flexural strength. On the other hand, for the corrosion rate, the samples were tested at 2 and 6 months. When nps-TiO2 and nps-ZnO samples were compared to the control sample, 2.5% and 1% of nps-TiO2 and nps-ZnO, respectively, showed the largest improvement in resistance to corrosion. Also, the self-cleaning property of the samples containing nano-materials (nps-TiO2 and nps-ZnO) was tested. As the results illustrated, the self-cleaning property of the samples was increased over time due to photocatalytic degradation. Furthermore, the results of the photocatalytic tests showed that nps-TiO2 samples outperformed nps-ZnO samples overall.
Novel Calculation Method for the Shear Capacity of a UHPC Beam with and without Web Reinforcement
Authors: Gao Chuansong , Jiang Hui , Zhang Gaozhan , Chen Liang , Hu Yuqing
Published: October 2023

To accurately predict the shear-bearing capacity of UHPC beams, it is crucial to quantify the shear contribution of the fiber bridging effect and UHPC compression zone. Nevertheless, it should be noted that the shear contribution of UHPC in the compression zone is not fully considered in most existing calculation methods, and the probability distribution of fibers within the matrix is also not taken into full account, which reduces the calculation accuracy of the shear bearing capacity of UHPC beams. In this paper, a UHPC beam shear test database containing 247 samples was created, and the influencing factors on the shear capacity of UHPC beams, such as the shear span ratio, the web reinforcement ratio, and the volume fraction of steel fiber, were analyzed. It was found that the ratio of cracking load to ultimate load ranges from 0.2 to 0.6, and the failure in the compression zone of UHPC beams can be divided into diagonal tension failure and shear compression failure. Based on the failure mechanism of the compression zone, considering the contribution of fiber micro tensile strength, a formula for calculating the shear-bearing capacity of UHPC beams with and without web reinforcement was proposed. Verified by experimental data, the proposed formula accurately predicts the shear-bearing capacity of UHPC beams. In comparison with other shear capacity formulas in current design codes, the proposed formula in this paper provides a higher prediction accuracy.
Built-In Piezoelectric Nanogenerators Promote Sustainable and Flexible Supercapacitors: A Review
Authors: Meng Shuchang , Wang Ning , Cao Xia
Published: October 2023

Energy storage devices such as supercapacitors (SCs), if equipped with built-in energy harvesters such as piezoelectric nanogenerators, will continuously power wearable electronics and become important enablers of the future Internet of Things. As wearable gadgets become flexible, energy items that can be fabricated with greater compliance will be crucial, and designing them with sustainable and flexible strategies for future use will be important. In this review, flexible supercapacitors designed with built-in nanogenerators, mainly piezoelectric nanogenerators, are discussed in terms of their operational principles, device configuration, and material selection, with a focus on their application in flexible wearable electronics. While the structural design and materials selection are highlighted, the current shortcomings and challenges in the emerging field of nanogenerators that can be integrated into flexible supercapacitors are also discussed to make wearable devices more comfortable and sustainable. We hope this work may provide references, future directions, and new perspectives for the development of electrochemical power sources that can charge themselves by harvesting mechanical energy from the ambient environment.
Preparation of NaYF4:Tm, Yb, and Gd Luminescent Nanorods/SiO2 Nanospheres Composite Thin Film and Its Application in Perovskite Solar Cells
Authors: Luo Qi , Yu Jian , Deng Xueshuang , Cao Ming , Ma Shifang , Hua Qiongxin , Xue Dan , An Fenghui
Published: October 2023

In this study, we aim to minimize light loss and achieve high power conversion efficiencies (PCE) in perovskite solar cells (PSCs) by employing a spectral conversion film component with antireflection properties. In our scheme, NaYF4:Tm, Yb, and Gd luminescent nanorod/silica nanosphere-based thin films are applied on CH3NH3PbI3 PSCs to improve the device efficiency. The film was fabricated by spin coating an aged silica sol containing NaYF4:Tm, Yb, and Gd luminescent nanorods. The size and the spectral conversion properties of the NaYF4:Tm, Yb, and Gd luminescent nanorods were controlled by tuning the Gd3+ ion concentration. The microstructure and the transmittance properties of the thin film were controlled by changing the concentration of NaYF4:Tm, Yb, and Gd luminescent nanorod in silica sol. The thin films have excellent spectral conversion properties while exhibiting a maximum transmittance. The photovoltaic performance of PSCs with NaYF4:Tm, Yb, and Gd luminescent nanorod/silica nanosphere-based thin films was systematically investigated. The light transmittance was optimized to 95.1% on a cleaned glass substrate, which resulted in an average increase of about 3.0% across the broadband range of 400–800 nm. The optimized films widen the spectrum of light absorbed by conventional PSC cells and reduce reflections across a broad range, enhancing the photovoltaic performance of PSCs. As a result, the PCE of the PSC increased from 14.51% for the reference device without a thin film to 15.67% for the PSC device with an optimized thin film. This study presents a comprehensive solution to the problem of Fresnel reflection and spectral response mismatch of the PSCs, which provides new ideas for the light management of PSCs.
A Thermomechanical Model for Time-Varying Deformations of Spigot Interference Connection under Shrink-Fitting Assembly
Authors: Zhu Junjiang , Yuan Bo , Mao Yibai , Zhou Ping , Sun Qingchao , Fang Guozhen
Published: October 2023

The interference fit connection structure is widely employed in various industries. Different from the conventional connection structure, the aero-engine rotor connection has a spigot-bolt structure. The quality of the shrink-fitting assembly process directly affects the final assembly performance of the rotor. The complexity of the connection structure and the time-varying thermal deformation bring great challenges in analyzing the formation patterns of connection performance. However, existing methods of interference connection analysis are mainly used in the wide range of interference connection structures, which makes them difficult to apply in low height interference connection for aero-engine rotors. This paper introduces a thermomechanical interference fit pressure model. First, a theoretical model for interference fit pressure considering temperature-variable loads is established to obtain the time-varying pressure during the assembly process. Second, a finite element model is established to explore the influence of interference and temperature loads on the spigot pressure and the mounting edge deformation. Finally, the experiments validate the accuracy of both the theoretical model and the finite element analysis. The results indicate that during the shrink-fitting assembly process, the interference fit pressure exhibits a nonlinear evolution trend, and the warping deformation of the mounting edge is a result of the combined influence of temperature and interference fit pressure. The law found in this paper has an application prospect in the process parameter setting of shrink-fitting assembly for special structures.
Design and Implementation of Hardware-in-the-Loop Simulation Environment Using System Identification Method for Independent Rear Wheel Steering System
Authors: Moon Chulwoo
Published: October 2023

In the automotive field, with the advancement of electronic and signal processing technologies, active control-based chassis systems have been developed to enhance vehicle stability. In this study, a Hardware-in-the-Loop (HiL) simulation environment was developed to effectively improve time and cost during the development process of an independent rear-wheel steering system. The HiL Simulation Environment was developed—a specific test bench capable of simulating driving loads on the prototype. Based on the system identification method, a reaction force modeling technique for the target driving loads was proposed. The full vehicle dynamics simulation model was developed with a lateral maximum error of 4.5% and a correlation coefficient of 0.98, as well as a longitudinal maximum error of 0.1% and a correlation coefficient of 0.99. The reaction force generation system had a maximum error of 2.9%. Using the developed HiL simulation environment, performance verification and analysis of the independent rear-wheel steering system were conducted, showing reductions of 5.1% in lateral acceleration and 5.2% in yaw rate.
Towards Robust and Effective Passive Compliance Design of End-Effectors for Robotic Train Fluid Servicing
Authors: Eshraghi Kourosh , Wang Mingfeng , Mares Cristinel
Published: October 2023

Without mechanical compliance robots rely on controlled environments and precision equipment to avoid clashes and large contact forces when interacting with an external workpiece, e.g., a peg-in-hole (PiH) task. In such cases, passive compliance devices are used to reduce the insertion force (and in turn the robot payload) while guiding corrective motions. Previous studies in this field are limited to small misalignments and basic PiH geometries inapplicable to prevalent robotic and autonomous systems (RASs). In addition to these issues, our work argues that there is a lack of a unified approach to the development of passive compliance systems. To this end, we propose a higher-level design approach using robust engineering design (RED) methods. In a case study, we demonstrated this general approach with a Taguchi design framework, developing a remote centre compliant (RCC) end-effector for robotic train fluid servicing. For this specific problem, a pseudo-rigid-body model (PRBM) is suggested in order to save enormous computation time in design, modelling, and optimisation. Our results show that the compliant end-effector is capable of significantly reducing the insertion force for large misalignments up to 15 mm and 6 degrees.
Analysis of Vacation Fluid M/M/1 Queue in Multi-Phase Random Environment
Authors: Ammar Sherif I. , Alharbi Yousef F. , Zhao Yiqiang Q.
Published: October 2023

An M/M/1 fluid queue with various vacations is studied in the context of a multi-phase random environment. When the system is in operation (i = 1, 2, …, n), it behaves according to the M/M/1 fluid queue model. However, in any other situation, the system is on vacation, so this leads it to transition into the vacation phase (i = 0). This transition occurs only when there is no data in the system. If the system returns from a vacation and finds it still empty of jobs, it will initiate a new vacation and continue in this pattern until jobs become available in the system, at which point it resumes working. When the vacation phase ends, the probability of the system transitioning to the operational phase is denoted as qi(i = 1, 2, …, n). Subsequently, we derive the stationary probability and analyze the buffer content in relation to the modified Bessel function of the first kind. We utilize the generating function approach and the Laplace–Stieltjes transform to achieve this, enabling us to accomplish our objectives. We provide numerical results to elucidate the overall behavior of the system under consideration.
Robust DDoS Attack Detection Using Piecewise Harris Hawks Optimizer with Deep Learning for a Secure Internet of Things Environment
Authors: Ragab Mahmoud , M. Alshammari Sultanah , Maghrabi Louai A. , Alsalman Dheyaaldin , Althaqafi Turki , AL-Ghamdi Abdullah AL-Malaise
Published: October 2023

The Internet of Things (IoT) refers to the network of interconnected physical devices that are embedded with software, sensors, etc., allowing them to exchange and collect information. Although IoT devices have several advantages and can improve people’s efficacy, they also pose a security risk. The malicious actor frequently attempts to find a new way to utilize and exploit specific resources, and an IoT device is an ideal candidate for such exploitation owing to the massive number of active devices. Especially, Distributed Denial of Service (DDoS) attacks include the exploitation of a considerable number of devices like IoT devices, which act as bots and transfer fraudulent requests to the services, thereby obstructing them. There needs to be a robust system of detection based on satisfactory methods for detecting and identifying whether these attacks have occurred or not in a network. The most widely used technique for these purposes is artificial intelligence (AI), which includes the usage of Deep Learning (DL) and Machine Learning (ML) to find cyberattacks. The study presents a Piecewise Harris Hawks Optimizer with an Optimal Deep Learning Classifier (PHHO-ODLC) for a secure IoT environment. The fundamental goal of the PHHO-ODLC algorithm is to detect the existence of DDoS attacks in the IoT platform. The PHHO-ODLC method follows a three-stage process. At the initial stage, the PHHO algorithm can be employed to choose relevant features and thereby enhance the classification performance. Next, an attention-based bidirectional long short-term memory (ABiLSTM) network can be applied to the DDoS attack classification process. Finally, the hyperparameter selection of the ABiLSTM network is carried out by the use of a grey wolf optimizer (GWO). A widespread simulation analysis was performed to exhibit the improved detection accuracy of the PHHO-ODLC technique. The extensive outcomes demonstrated the significance of the PHHO-ODLC technique regarding the DDoS attack detection technique in the IoT platform.
On Solving Stochastic Optimization Problems
Authors: Blăjină Ovidiu , Ghionea Ionuţ Gabriel
Published: October 2023

Many optimization mathematical models, associated with the technical-economic processes of real-world problems, have elements of uncertainty in their structure, which places them in stochastic optimization programming. Their diversity and complexity, due to the large uncertainty space, require special methods of solving, because there is no general solution method. Within this context, in this paper we consider the category of optimization models that can contain random variable type coefficients and/or imposed probability levels on the constraints. The purpose of the paper is to propose a methodology dedicated to these studied models. Applying the methodology leads to developing a deterministic linear programming model, associated with the initial stochastic model. In fact, the proposed methodology reduces the stochastic formulation to a deterministic formulation. The methodology is illustrated with a numerical case study based on a manufacturing problem. Solving the obtained deterministic model is carried out in the version assisted by a specialized software product (WinQSB Version 2.0). It allows for the performing of a sensitivity analysis of the optimal solution, and/or a parametric analysis relative to certain model coefficients, both also presented in the paper. The main result of the study in this paper is the proposed methodology, which is applicable on a large scale, for any mathematical model of stochastic optimization of the mentioned type, regardless of complexity, dimensions and the domain of the process to which it is associated. The numerical results obtained when applying this methodology indicate its efficiency and effectiveness in finding the solution for the studied models. The approach to this issue in the present paper is determined by the wide range of stochastic optimization problems in the various studied real-life processes and by the imperative need to adopt the best decisions in conditions of uncertainty.
Solitons Equipped with a Semi-Symmetric Metric Connection with Some Applications on Number Theory
Authors: Hakami Ali H. , Siddiqi Mohd. Danish , Siddiqui Aliya Naaz , Ahmad Kamran
Published: October 2023

A solution to an evolution equation that evolves along symmetries of the equation is called a self-similar solution or soliton. In this manuscript, we present a study of η-Ricci solitons (η-RS) for an interesting manifold called the (ε)-Kenmotsu manifold ((ε)-KM), endowed with a semi-symmetric metric connection (briefly, a SSM-connection). We discuss Ricci and η-Ricci solitons with a SSM-connection satisfying certain curvature restrictions. In addition, we consider the characteristics of the gradient η-Ricci solitons (a special case of η-Ricci soliton), with a Poisson equation on the same ambient manifold for a SSM-connection. In addition, we derive an inequality for the lower bound of gradient η-Ricci solitons for (ε)-Kenmotsu manifold, with a semi-symmetric metric connection. Finally, we explore a number theoretic approach in the form of Pontrygin numbers to the (ε)-Kenmotsu manifold equipped with a semi-symmetric metric connection.