bluuebunny/crossref_metadata_2025 huggingface dataset:
Efecto de la cosecha mecanizada sobre la calidad del grano de maíz para la recepción y el procesamiento agroindustrial
Authors: Ruiz-Silvera Carlos , Ávila-Ramírez Manuel , Alezones-Gómez Jesús , Romero-Hernández Marbella , Tona-Hernández Henry
Published: October 2018

En Venezuela, el maíz es el cereal de mayor importancia alimentaria. Cada año se cultivan cientos de miles de hectáreas de maíz blanco y amarillo, que son destinados en un alto porcentaje al procesamiento en la industria de alimentos para consumo humano y animal. En las principales zonas productoras de maíz predomina la cosecha mecanizada, cuyos efectos y parámetros de eficiencia no están bien documentados. Con el propósito de suplir esta carencia, se determinaron los efectos de la cosecha mecanizada sobre parámetros de calidad del grano en híbridos comerciales y experimentales de maíz, en localidades de los estados Portuguesa y Yaracuy, Venezuela, durante el ciclo de lluvias 2016. Se examinaron el contenido de humedad, las impurezas (IMPZ), y los atributos de calidad del grano, granos partidos (GPAR), granos con germen dañado (GGRD) y granos dañados por microorganismos (GDMO). Los contenidos de humedad a la cosecha (16,8% ± 1,7 en cultivares amarillos y 20,9% ± 1,1 en cultivares blancos) y de IMPZ (0,3% ± 0,3 en cultivares amarillos y en cultivares blancos), se ubicaron por debajo del límite tolerado para su uso en la industria (24% de humedad y 5% de impurezas). La cosecha mecanizada tuvo efectos sobre los atributos de calidad del grano evaluados, tanto en híbridos amarillos como en blancos. La cosecha mecánica tuvo su mayor impacto sobre los atributos de los granos partidos (GPAR) y los granos dañados por microorganismos (GDMO), y pudo afectar la inocuidad de la materia prima y la clasificación del lote de granos para el procesamiento industrial.
Análisis fenológico comparativo de las accesiones más productivas de un banco de germoplasma de Jatropha curcas (tempate), en Costa Rica
Authors: Castillo-Ugalde Marvin , Briceño-Elizondo Elemer , Arias-Aguilar Dagoberto , Moreira-González Ileana , Arnáez-Serrano Elizabeth
Published: October 2018

La especie Jatropha curcas (tempate) es típica de la zona mesoamericana, su centro de origen se ha establecido en México.  Ha sido domesticada para uso en  cercas vivas y por su valor medicinal según el conocimiento tradicional.  En la actualidad se cataloga como una especie de alto valor para la producción de aceites que pueden tener uso en biocombustibles o como diluyente de pinturas.  En Costa Rica se ha establecido un banco de germoplasma en la estación experimental Fabio Baudrit de la Universidad de Costa Rica, ubicada en la Garita de Alajuela.  Comprende un total de 52 accesiones procedentes de todo el país y algunas de ellas de origen internacional.  Producto del seguimiento anual del mismo se tuvo conocimiento de que las procedencias  Turrubares JCCR36 ,Jacó JCCR-3 ,El Barro de Turrubares JCCR-43,Orotina JCCR-1, Marichal JCCR-42, Tempate 1 JCCR-6, San Vito 2 JCCR-30, México 2 JCCR-31,India JCCR-27, Tempate 1-Guanacaste JCCR-23, fueron las más productivas y de cada una se seleccionaron 3 individuos a los que se les dio un seguimiento semanal estimando el número de flores femeninas, masculinas, número de inflorescencias, número de frutos.  A los datos se les aplicó un análisis no paramétrico de Kruskal Wallis y los resultados se correlacionaron con el nivel de irradiación y precipitación.  Lo que permitió estimar que las procedencias más productivas fueron San Vito 2 JCCR-30, México 2 JCCR-31 y Tempate 1-Guanacaste-23.   La mayor tasa de irradiancia se registró en los meses de febrero- marzo en el 2014 y marzo-abril en el 2015, se encontró correlaciones inversas mayores a 0,40 entre la radiación solar para los años 2014 y 2015, con respecto a la producción de flores, mientras que el comportamiento de la producción de inflorescencias presentó correlaciones con la precipitación y la radiación solar.
Desarrollo sostenible. Aplicabilidad y sus tendencias
Authors: Madroñero-Palacios Sandra , Guzmán-Hernández Tomás
Published: October 2018

El presente artículo tiene como finalidad desarrollar un recorrido en torno al concepto de desarrollo sostenible, iniciando con los antecedes que preceden su generación, analizando su definición e implicaciones, para luego identificar sus componentes: social, económico y ecológico. Se profundiza su análisis a través de diferentes enfoques: contextual, conceptual, disciplinar y geopolítico; estableciendo sus limitantes en la claridad del concepto y en su aplicabilidad. Se resalta los tipos de sostenibilidad, muy fuerte, fuerte y débil y  la influencia que ha tenido el sistema económico actual para determinar, el tipo de interrelación entre los diferentes componentes del sistema, resaltando el papel preponderante que debe tener la conservación del sistema ecológico como proveedor de los insumos que permiten potencializar el sistema social y económico. Así mismo, se analiza las diferencias sustanciales entre sostenibilidad y sustentabilidad ahondando en su origen y significado. Finalmente se realiza un breve análisis acerca de las implicaciones del cambio climático y las medidas de mitigación y adaptación que se hace necesario tomar para responder a una problemática en crecimiento que pone en riesgo el alcance de lo que se conoce como sostenibilidad.
A Simulation Based Approach for Efficient Yard Planning in a Container Port
Authors: Çolak Murat , Aydın Keskin Gülşen , Esen Hatice , Bektaş Canan
Published: October 2018

Maritime transport is the most significant one among
several transportation modes. Containers are transported at international level
as a part of maritime transport. Seaports have critical role for efficiency of
container stacking process. It is necessary to complete operations of arriving
vessels at the shortest time in order to provide high customer satisfaction. At
this point, simulation is effectively utilized as a decision support system in
order to improve port processes. In this study, current situation and two
alternative scenarios are compared to each other through simulation so as to
realize the most suitable stack planning by removing bottlenecks in a container
port. It is aimed to determine the most suitable yard layout to provide
minimization of discharging times for arriving vessels, decreasing waiting
times of carriers under quay and yard cranes and fair usage of all equipment.
Thus, it is planned to reduce energy and workforce costs.
On Concircular Curvature Tensor in Space-Times
Authors: Kırık Bahar
Published: October 2018

The aim of this work is to examine some properties of the concircular curvature tensor on $4-$dimensional manifolds admitting a Lorentz metric (so called space-times). In the first two sections, the study is introduced and the interrelated concepts together with some notations are presented. In the third section of the study, some results are obtained connected to eigenbivector structure of the concircular curvature tensor on these manifolds by taking into account the classification scheme of 2--forms (also known as bivectors) in this metric signature. Then, the known holonomy algebras on space-times are considered and some theorems are given regarding the concircular and Riemann curvature tensors. This analysis is also associated with the types of the Riemann curvature tensor on these manifolds. In the last section, the results of the study is summarized and the discussion part is presented.
Bazı Kişniş (Coriandrum sativum L.) Genotiplerinin Isparta Koşullarında Verim ve Kalite Özelliklerinin Belirlenmesi
Authors: Gökduman Göksel Ali , Telci İsa
Published: October 2018

Bu

çalışmada; ıslah edilmiş kişniş çeşit ve hatlarının Isparta ekolojik koşularına

uyumu ile verim ve kalite özelikleri araştırılmıştır. Çalışma 2017 vejetasyon

döneminde Süleyman Demirel Üniversitesi, Tarımsal Araştırma ve Uygulama Merkezi

arazilerinde yürütülmüştür. Çalışmada Arslan, Erbaa, Pelmus, Kudret K. Gamze,

Gürbüz tescilli çeşitler ile saflaştırılmış Tokat K, Tokat B ve Mardin hatları

kullanılmıştır. Tarla denemesi tesadüf blokları deneme desenine göre üç

tekrarlamalı olarak yürütülmüştür. Çalışma sonucunda en yüksek biyolojik verim

(450 kg/da) ve meyve verimi (113 kg/da) Erbaa çeşidinden elde edilmiştir. Uçucu

yağ ve sabit yağ oranları sırasıyla  %

0.17-0.33 ile %18.64-22.16 aralıklarında bulunmuştur. Çalışma sonucunda, kozmetik

sektörünün önemli olduğu Isparta koşullarında kişniş bitkisinden maksimum 113

kg/da meyve verimi alınabileceği ve bölgenin kişniş üretimi için uygun olduğu

belirlenmiştir.  Çalışmada ayrıca Erbaa

çeşidinin diğer çeşitlerden daha yüksek verim verdiği belirlenmiştir.
Severe Pseudotumor Formation on an Asymptomatic Well Functioning Metal-On-Metal Total Hip Arthroplasty - A Case Report and Follow - Up
Authors: ÖZCAN Hakan , ÖNDER Hacı
Published: October 2018

A 72-year-old patient who had metal-on-metal (MMO) total hip arthroplasty
(THA) 7 years ago has developed a gluteal mass and pain. Plain radiographs
showed a well-fixed THA on the left side with an increased acetabular
inclination. Needle aspiration of the mass showed “milky stained” highly
viscous liquid. After the approval of the patient, a revision total hip
arthroplasty had been performed. There were severe necrosis and granulomatous
type reactions all around the hip and the components. After extensive
debridement, all the components were removed and a long-stemmed revision total
hip arthroplasty with polyethylene insert was performed. We think that patients
with MMO THA must be carefully reviewed after the surgery even if they are
asymptomatic.
Antalya Kaleiçi Sokaklarının Bitki Materyali Ve Bitkisel Tasarım Açısından Değerlendirilmesi
Authors: KÖSA Selma
Published: October 2018

Canlı varlıklar olan
bitkiler, Peyzaj Mimarlığı mesleğinin en önemli tasarım materyalleridir. Bitkilerin
kullanıldıkları mekânlarda yapısal ve bitkisel diğer materyallerle olan
ilişkilerini istenilen şekilde düzenleyebilmek için bitkisel tasarım ilkelerini
göz önünde bulundurmak gerekir. Araştırmanın amacı, Antalya Kaleiçi sokaklarında
bulunan bitki türlerinin belirlenmesi, bu sokakların bitkisel tasarımlarının
çeşitlilik, tekrar, vurgu ve denge ilkelerine göre değerlendirilmesi ve sokak
özellikleri ile bitkisel tasarım ilkeleri arasındaki ilişkilerin analiz
edilmesidir. Sokakların tasarım ilkesine göre değerlendirilmesinde, temel
tasarım öğeleri olan form, renk, doku ve ölçü unsurlarının kullanılma durumları
sorgulanmıştır. Antalya Kaleiçi sokaklarında 127 farklı bitki türü olduğu, 70
türün de sadece saksılı ve 21 türün sadece yere dikim olarak kullanılırken 36
türün ise hem saksılı hem de yere dikim olarak kullanıldığı belirlenmiştir. Değerlendirilen
63 sokaktan 6’sının, bitkisel tasarımda çeşitlilik, tekrar, vurgu ve denge
ilkelerini başarılı bir şekilde sağladığı tespit edilmiştir. Sokaklarda yere
dikim bitki tür sayıları, saksılı olarak kullanılmış bitki tür sayıları ve toplam
tür sayıları ile tasarım ilkeleri arasındaki ilişkiler istatistiksel anlamda
önemli bulunmuştur. Sonuç olarak, Antalya Kaleiçi sokaklarında bitkisel tasarım
ilkelerinin sağlanmasında bitki tür sayısının etkili olduğu, aynı zamanda
sokaklarda bitkilerin yere dikim veya saksılı olarak kullanımının farklı etkiler
yarattığı ve sokak uzunluğu ile sokak genişliğinin de bitkisel tasarımı
etkilediği belirlenmiştir.
Patrimônio fabril e historia urbana no bairro do Reduto em Belém (PA)
Authors: Vidal Celma Chaves de Souza Pont , Oliveira Douglas Nélio Lima de
Published: October 2018

O bairro do Reduto, em Belém, Pará, apresenta um processo de modernização intrinsecamente relacionado à instalação das primeiras fábricas da capital, desde a última década do século XIX. Estas atividades fabris se iniciam com a extração e exportação do látex, e começam a arrefecer a partir do final dos anos 50, porém, as portas da últimas fábricas se fecham na década de 70, quando a abertura de novas rodovias desestabilizam o setor produtivo da Amazônia, facilitando o acesso dos produtos vindos do sul e sudeste do país. Este artigo propõe-se a refletir sobre alguns dos edifícios fabris do bairro em sua relação com a historia urbana de Belém, considerando sua importância como patrimônio arquitetônico, as transformações pelas quais passaram, e a situação atual da área que abrigou algumas das principais indústrias da capital do Pará.
O modelo das duas rodas: uma referência para o sistema de gestão da inovação em pequenas e médias empresas
Authors: Silva Iara Sibele , Libório Matheus Pereira , Bernardes Patrícia , Ramalho Felipe
Published: October 2018

O modelo das duas rodas: uma referência para o sistema de gestão da inovação em pequenas e médias empresas de Bagno & Faria (2017) descreve as bases teóricas e metodológicas do programa de organização, direcionamento e sistematização da gestão da inovação da Federação das Indústrias de Minas Gerais, implantado em 43 empresas. Nesta resenha, analisamos a adequação das bases teóricas e metodológicas da obra com a realidade das empresas.
Slope Compensation Design for a Peak Current-Mode Controlled Boost-Flyback Converter
Authors: Muñoz Juan-Guillermo , Gallo Guillermo , Angulo Fabiola , Osorio Gustavo
Published: October 2018

Power converters with coupled inductors are very promising due to the high efficiency and high voltage gain. Apart from the aforementioned advantages, the boost-flyback converter reduces the voltage stress on the semiconductors. However, to obtain good performance with high voltage gains, the controller must include two control loops (current and voltage), and a compensation ramp. One of the most used control techniques for power converters is the peak current-mode control with compensation ramp. However, in the case of a boost-flyback converter there is no mathematical expression in the literature, to compute the slope of the compensation ramp. In this paper, a formula to compute the slope of the compensation ramp is proposed in such a way that a stable period-1 orbit is obtained. This formula is based on the values of the circuit parameters, such as inductances, capacitances, input voltage, switching frequency and includes some assumptions related to internal resistances, output voltages, and some other electrical properties related with the physical construction of the circuit. The formula is verified numerically using the saltation matrix and experimentally using a test circuit.
Systematic Understanding of the Mechanism of Pristimerin via Computational Target Fishing
Authors: Li Zaiyu , Hu Cong , Zhen Yu , Pang Bo , Yi Huanfa , Chen Xianglin
Published: October 2018

Pristimerin (PM) is a naturally occurring quinonemethide triterpenoid compound that isolated from the Celastraceae and Hippocrateaceae families. Its anticancer effects have attracted a great deal of attention, but the mechanisms of action remain obscure. In this study, we screened for the active compounds of Pristimerin using a drug-likeness approach. Potential protein targets of Pristimerin were predicted by PharmMapper and Coremine database. Candidate protein targets were then uploaded to GeneMANIA and GO pathway analysis. Finally, compound-target, target-pathway, and compound-target-pathway networks were constructed using Cytoscape 3.3. The results showed that Pristimerin had good drug ability and identified 13 putative protein targets. Network analysis revealed that these targets are associated with cancer, inflammation and other physiological processes. In summary, Pristimerin is predicted to target a variety of proteins and pathways to form a network that exerts systemic pharmacological effects.
Chemotherapeutic Drug Functionalized Nanoparticles are Beneficial When Treating Breast Cancer Via Magnetic Hyperthermia
Authors: Piehler Susann , Dähring Heidi , Grandke Julia , Göring Julia , Couleaud Pierre , Aires Antonio , Cortajarena Aitziber L. , Courty José , Latorre Alfonso , Somoza Álvaro , Miranda Rodolfo , Hilger Ingrid
Published: October 2018

Doxorubicin (DOX) is a frequently used chemotherapeutic drug for breast cancer, but its site specificity and local internalization into tumor cells is rather low. In this paper we conjugated magnetic nanoparticles (MNPs) with DOX and/or a pseudopeptide NucAnt (N6L) as modality to enhance DOX-induced antitumor effects in breast cancer cells (BT474). In this context, we determined cellular uptake of MNP formulations, analyzed cell viability and expression of apoptotic and cell cycle proteins after magnetic hyperthermia (43°C, 1 h) in vivo and in vitro. We have shown that i) the presence of N6L on the surface of DOX-functionalized MNPs increases their internalization into a target cells and potentiates the cytotoxic potential of the anticancer drug, ii) in combination with hyperthermia, DOX functionalized MNPs influence the expression of apoptotic and cell cycle proteins, and also favors tumor regression in vivo. Our data show that intratumoral application of DOX coupled MNPs is able to overcome biological barriers to chemotherapeutic drugs, enabling them to penetrate into the target cells. Combined with hyperthermia these MNPs can be an effective method in enhancing the localised delivery and penetration of DOX into breast cancer cells.
Coexistence of Different Scaling Laws for the Entanglement Entropy in a Periodically Driven System
Authors: Apollaro Tony J. G. , Lorenzo Salvatore
Published: October 2018

The out-of-equilibrium dynamics of many body systems has recently received a burst of interest, also due to experimental implementations. The dynamics of both observables, such as magnetization and susceptibilities, and quantum information related quantities, such as concurrence and entanglement entropy, have been investigated under different protocols bringing the system out of equilibrium. In this paper we focus on the entanglement entropy dynamics under a sinusoidal drive of the tranverse magnetic field in the 1D quantum Ising model. We find that the area and the volume law of the entanglement entropy coexist under periodic drive for an initial non-critical ground state. Furthermore, starting from a critical ground state, the entanglement entropy exhibits finite size scaling even under such a periodic drive. This critical-like behaviour of the out-of-equilibrium driven state can persist for arbitrarily long time, provided that the entanglement entropy is evaluated on increasingly subsytem sizes, whereas for smaller sizes a volume law holds. Finally, we give an interpretation of the simultaneous occurrence of critical and non-critical behaviour in terms of the propagation of Floquet quasi-particles.
The Turn to Overall Sustainable Social Transformation: Does it Real?
Authors: Martynov Arkady
Published: October 2018

The paper is devoted to fundamental issues concerning to the ideology of the future sustainable development. Its implementation has available in the first place basing on the recognized framework concept of sustainable development (SD). At the same time, this concept requires serious improvement. As follows from the argumentation, a realistic design of institutional changes in connection with resource and organizational/behavioral changes needed for SD is called for to realize in the line of overall social system transformation. Its adequate understanding presupposes an exhaustive study of interconnected transformations in the main social fields as system processes taking into account the influence of relatively exogenous factors (technological, demographic and climate changes).According to the author, the transition to global sustainable social transformation is achievable. Main attention focuses on a number of possible fundamental shifts, the synergetic implementation of which will make such a transition possible.Proceeding from the arguments, the sustainable reproduction of the economy of a mature post-industrial type, including the green sectors, implies its stable and quiet growth, although the rapid growth of individual markets, especially innovative ones, may take place. The main findings also include the substantiation in favor of the choice of the national middle way model as the most appropriate for the corresponding sustainable system transformation of society.
Emergence of Standard-Model-Like Fields and Particles in Gravitation-Diffusion Vacuum
Authors: Manasson Vladimir A.
Published: October 2018

A number of experiments suggest that the elementary particles are non-local entities. A dissipative self-organization, that treats particles as open systems may provide a better understanding of the underlying phenomena than conservative models. The proposed toy model is such an attempt. We found that self-gravitation (although accompanied by self-diffusion) may not only be compatible with the quantum phenomena but is perhaps the major reason for the existence of quantum fields. According to the proposed model, fields/particles (resemble those of the Standard Model) emerge from a dynamic self-organized medium (which we associate with vacuum dust) from competition between self-gravitation and self-diffusion. These forces produce turbulence in the form of vortices (which we call vacuum cells) that serve as the building blocks for fields and particles. Field/particle features and symmetries are based on their internal (intracellular) dynamics and vortex synchronization (intercellular dynamics). This model allows for rough estimations of relative field coupling strengths, the quantity of charges and flavors, the probabilities of quark transmutations, the dimensionality and the topologies of phase spaces, and other Standard Model parameters that came not from the theory but rather determined by experiment.
Statistical Analysis of Raageshwari Deep Gas Fracturing and Production Logging Data for Understanding Fracture Performance and Future Optimization
Authors: Bhardwaj Charu , Ranjan Vishal , Pathak Shashank , Tiwari Shobhit , Tripathi Archit , Beohar Abhudai
Published: October 2018

Raageshwari Deep Gas field situated in southern Barmer Basin of India is a retrograde gas condensate volcanic reservoir. More than 150 fracturing treatments have been pumped in this reservoir to achieve sustained economical production. The paper describes the results of a statistical analysis done to find correlations between production data and fracturing design parameters including petrophysical and geo-mechanical properties of the rock, pre-frac diagnostic tests, and fracturing treatment data including both pumping data and pressure matched parameters.

This paper uses the data from multiple production logs to generate stage wise Productivity Index (PI). This PI data was then cross plotted against various parameters and combinations of parameters such as In-situ proppant concentration, formation porosity, net pay, average stress, proppant mass pumped per stage, fracturing fluid recovery rate and percentage, and fracture dimensions. One interesting line of investigation looked at the rate of pressure decline post Step Rate Test (SRT). A method was developed to evaluate the SRT declines even though they were too short to analyze for permeability using post closure analysis.

This paper presents the results of these statistical analysis and where reasonable correlations were obtained. It also shows that for this volcanic formation, the rate of pressure decline after the SRT is a better indicator of Reservoir Quality (RQ) and future stage performance than the log derived porosity and permeability. While the use of short term fall-off data is only qualitative, it does appear to be an effective tool for evaluating the potential of a stage just before fracturing which would allow improved onsite treatment optimization.

Since the quality of a reservoir generally varies across the areal extent of a field, it is very important to ascertain the same either qualitatively or quantitatively. This paper presents a technique for qualitatively defining RQ, which can be useful to validate the pre-existing workflows used for defining RQ.
INFLUENCE OF BEEF MARBLING SCORE ON QUALITY INDICATORS DURING MEAT AGING
Authors: Kozyrev Il`ya A. , Mittelshtein Tat`yana M. , Kuznetsova Tat`yana G. , Pchelkina Viktoriya A. , Spiridonov Kiril I. , Lisitsyn Andrey B.
Published: October 2018

In the experiment, beef samples were used with the marbling scores «moderate» and «good» (n = 4). Half of the samples were packaged in a plastic film under vacuum, while the rest ones were left unpackaged. Aging was carried out for 4, 16, and 28 days in a storage chamber at a temperature of 2 ± 1 °C and a relative humidity of not more than 90 %. During beef aging, pH, sensory indicators of quality and freshness, microstructural indicators, and shear force were evaluated. Regardless of the marbling score, on day 28, sensory indicators of unpackaged beef had the signs of non-fresh meat, while the packaged samples had no deviations. Regardless of the marbling score, sensory evaluation indicated the high quality of boiled meat and broth during the entire aging period for packaged beef and during 16 days for unpackaged beef. Histological studies found that with the increase in beef aging period, the destructive changes in tissues increased as well. On days 16 and 28, samples of packaged beef, both with marbling score «good» and «moderate», corresponded to the second and third stage of meat aging. Changes in unpackaged beef at the corresponding days of aging were less pronounced. The results of a shear force study indicated that, during the entire observed aging period, a gradual decrease in shear force occurred.
THE PROPERTIES OF THE CONIDIA OF STRAINS OF THE ACTINOMYCETE STREPTOMYCES LUCENSIS AND STREPTOMYCES VIOLACEUS DURING STORAGE AT LOW TEMPERATURES
Authors: Sharova Natalya Yu. , Vybornova Tatyana V. , Printseva Anastasia A. , Manzhieva Bairta S.
Published: October 2018

Collection cultures of actinomycetes are mainly stored in a dried state on adsorbents. Practiced low-temperature storage of actinomycetes at minus 70°C. The article presents the results of investigations of the properties of the conidia of strains of the actinomycete Streptomyces lucensis VKPM Ac–1743 and Streptomyces violaceus VKPM Ac–1734 is in the process of storage at minus 12°C and minus 18°C in glycerin solution and in 0,9 % aqueous sodium chloride solution. It was found that the inhibitory activity in the native solution for the studied strains stored in the glycerin solution at minus 12°C and plus 4°C, as a result of their subsequent cultivation on the starch hydrolyzate for 120 h is at the level of (450 ± 10) IE/cm3. The indicator for crops stored at minus 18°C was higher (560 ± 10) IE/cm3. Low-temperature storage of conidia in saline solution is less effective. Pigmentation is more active in the cultivation of strains stored at minus 18°C.
PHYSICAL AND CHEMICAL FEATURES OF DYNAMIC OF POLYMERIC FLUID
Authors: Karimov Alexander R. , Taleysnik Mikhail A. , Savenkova Tat’yana V. , Aksenova Larisa M. , Gerasimov Timofei V.
Published: October 2018

In order to determine the nature of processes of the dynamic polymer flow with simple chemical reactions in two-dimensional cylindrical geometry, objects — a sugar melt and a high molecular weight fraction of glutenin of flour — were chosen in the hydrodynamic description, which were investigated on a rotational rheometer HAAKE RotoVisco 1 and the Moisture Analyzer OHAUS MB23. The nonlinear dynamics of a viscous flow of a compressible, homogeneous liquid with chemical reactions is considered. A nonstationary exact solution of the Poiseuille type is obtained. This solution is used to investigate the effect of viscosity and chemical reactions of the first order on the characteristics of the nonequilibrium dynamic states of the system. The present results of the joint research of the specialists of the All-Union Research Institute of the Confectionery Industry and the MEPhI are a continuation of the work on the formation of structures in food disperse systems and indicate that similar features can also be manifested in real flows of polymer liquids in various industrial installations.
Practical use of modern guidelines for the diagnosis and treatment of exocrine pancreatic insufficiency in patients with chronic pancreatitis
Authors: Minushkin O. N. , Maslovsky L. V. , Evsikov A. E. , Chebotareva A. M.
Published: October 2018

The article presents a review of current European and Russian guidelines on diagnostics and treatment of exocrine pancreatic insufficiency in patients with chronic pancreatitis. Results of our own comparative study on treatment of 55 chronic pancreatitis patients with low and adequate doses of pancreatic enzyme replacement therapy (PERT) confirm the need for usage of recommended doses of modern micronized polyenzyme drugs since it improves both clinical manifestation and nutritional status in such patients unlike the lower doses. Our research findings show that the optimal criterium for PERT efficacy assessment is the normalization of antropometric and biochemical nutritional markers.
Inflammatory factor in the clinical picture and therapy of irritable bowel syndrome
Authors: Makhov V. M. , Balakhonov A. A. , Isaikina M. A. , Doronina Yu. A.
Published: October 2018

The article shows the dynamics of evaluation of prognostic factors of irritable bowel syndrome. Evolution of the views indicates an increasing evaluation of inflammation and the role of markers of inflammation of cytokines, especially alpha-TNF in clinical manifestations. The rationale for using a complex drug based on affinity purified release-active antibodies to alpha-TNF, to the brain-specific protein S-100 and histamine-colourant is presented.
Pharmacological approaches to the treatment of combined functional pathology (biliary and intestinal tract)
Authors: Minushkin O. N.
Published: October 2018

The article presents data on a new classification of functional disorders according to Rome IV criteria. Particular attention is given to the combined functional pathology - the overlap syndrome. The combination of functional biliary disorders (PBD) and irritable bowel syndrome (IBS) is the most common functional disorder. The tactic of conservative treatment - the choice of myotropic antispasmodic is considered. The analysis of the results of our own study of the efficacy of Niaspam in the treatment of abdominal pain, flatulence and stool disorders in patients with PBD and IBS are presented.
Correction of intestinal microbiocenosis as a preventive measure for progression of chronic kidney disease
Authors: Barilko M. S. , Seliverstov P. V. , Radchenko V. G. , Murzina A. A.
Published: October 2018

At present, much attention is paid to the study of the influence of gut microbiota on the development of many diseases of internal organs, including chronic kidney disease. Thus, changes of gut microbiota in the qualitative and quantitative composition toward increasing the proteolytic flora, which is the source of the formation of uremic toxins, endotoxinemia, systemic inflammation, secondary immunodeficiency and cardiovascular complications, contribute to the worsening of the course and the progression of chronic kidney disease. That why the use of medicines which normalize gut microbiota, is the significant aspect of preventing the progression of chronic kidney disease.
A randomized placebo-controlled clinical trial of a multi-strain probiotic formulation (Bio-Kult®) in the management of diarrheapredominant irritable bowel syndrome
Authors: Ishaque M.Sh. , Khosruzzaman S.M. , Ahmed D.S. , Sah M.P.
Published: October 2018

Background: Accumulating evidence supports the view that an imbalance of gut bacteria contributes to IBS, and that increasing the mass of beneficial species may reduce the numbers of pathogenic bacteria and help alleviate symptoms.

Methods: In this double-blind trial 400 adult patients with moderate-to-severe symptomatic diarrhea-predominant IBS (IBS-D) were randomized to treatment with the multi-strain probiotic Bio-Kult® (14 different bacterial strains) or placebo for 16 weeks. The change in severity and frequency of abdominal pain was the primary outcome measure.

Results: Probiotic treatment significantly improved the severity of abdominal pain in patients with IBS-D. A 69% reduction for probiotic versus 47% for placebo (p < 0,001) equates to a 145 point reduction on the IBS-severity scoring system (IBS-SSS). The proportion of patients who rated their symptoms as moderate-to-severe was reduced from 100% at baseline to 14% for the multi-strain probiotic at follow-up (month 5) versus 48% for placebo (p < 0,001). Also, the number of bowel motions per day from month 2 onwards was significantly reduced in the probiotic group compared with the placebo group (p < 0,05). In addition to relieving symptoms, the probiotic markedly improved all dimensions of quality of life in the 34-item IBS-Quality of Life (IBS-QoL) questionnaire. No serious adverse events were reported.

Conclusions: The multi-strain probiotic was associated with significant improvement in symptoms in patients with IBSD and was well-tolerated. These results suggest that probiotics confer a benefit in IBS-D patients which deserves further investigation. Trial registration: [Clinicaltrials.gov NCT03251625; retrospectively registered on August 9, 2017].
Expectorants: principles of choice and possibilities of modern herbal therapy
Authors: Lazareva N. B. , Ermakova V. A.
Published: October 2018

Herbal therapy occupies a special niche in the treatment of acute respiratory infections. The article discusses the causes and mechanisms of cough, as well as the possibility of its therapy with herbal drugs. It presents the multipurpose effect of phytopreparations on all components of the cough pathogenesis: they facilitate expectoration, improve the bronchial drainage, as well as the antimicrobial effect, which is an integral part of the treatment. The authors highlighted the compatibility of phytopreparations with other drugs for the treatment of respiratory pathology.
Avaliação da Sustentabilidade do Instituto Federal de Educação, Ciência e Tecnologia do Rio Grande do Norte
Authors: Silva José Irivaldo Alves Oliveira , Pinheiro André Luis Santos
Published: October 2018

Este trabalho tem como objetivo avaliar a sustentabilidade do Instituto Federal de Educação, Ciência e Tecnologia do Rio Grande do Norte por meio da investigação das ações de sustentabilidade implementadas nos campi, mensurando, em seguida, seus desempenhos em sustentabilidade. Utilizou-se fonte documental e a aplicação de lista de verificação proposta no Sistema Contábil Gerencial Ambiental – SICOGEA 2ª geração. Constatou-se a preocupação da instituição com a redução do consumo e da produção de resíduo e com sua destinação, assim como com a produção de energia fotovoltaica e ao tratamento e reuso de efluentes líquidos. Por outro lado, os resultados indicam que as ações de sustentabilidade não estão adequadamente articuladas, havendo uma sinalização recente de progresso no sentido de sistematização dessas ações.
Percepção Ambiental de Trabalhadores em Empresa Certificada ISO 14001: práticas e comportamentos
Authors: Aguiar Alexandre De Oliveira e , Ribeiro Cristiano Silveira , Nascimento Ana Paula Branco do
Published: October 2018

Empresas certificadas no Sistema de Gestão Ambiental ISO14001 desenvolvem programas para controle de seus aspectos ambientais por meio de procedimentos e práticas como coleta seletiva de resíduos, medidas de economia de energia e consumo de água, entre outros. A aplicação de práticas ambientais dentro da empresa pode influenciar a atitude ambiental do trabalhador fora dela. Este trabalho visa estudar as práticas ambientais aplicadas pelo trabalhador no interior de uma empresa, a correlação desta com a vida cotidiana e se essas práticas estão relacionadas com a atitude do trabalhador fora do ambiente profissional. Foram obtidas 147 respostas de um questionário desenvolvido especificamente para esta pesquisa com funcionários de uma empresa de tratamento de superfície de metais. Os resultados foram tratados analisando-se as correlações bivariadas entre as respostas. Além do questionário, foram obtidas informações operacionais e de gestão ambiental da empresa. A análise dos resultados triangulou ambas informações. Destaca-se que entre as assertivas ligadas a postura da empresa aquelas em que a atitude da liderança serve como estímulo ao comportamento ambientalmente responsável se correlacionou com o maior número de assertivas sobre comportamento do funcionário. Como resultado da pesquisa realizada concluiu-se que as ações de formação de desenvolvimento dos trabalhadores podem ser revistas no sentido de apresentar abordagens práticas a vida profissional e cotidiana e de forma a despertar no trabalhador a percepção ambiental sobre a relação de seus impactos internos e externos sobre o meio ambiente.
Desenvolvimento Humano dos Municípios de Mato Grosso e Mato Grosso do Sul Contidos no Bioma Pantanal
Authors: Scheuer Junior Miranda , Neves Sandra Mara Alves da Silva , Galvanin Edinéia Aparecida dos Santos , Neves Ronaldo José
Published: October 2018

Objetivou-se avaliar, por meio do Índice de Desenvolvimento Humano (IDHM) dos municípios do bioma Pantanal, o desenvolvimento humano da fundação e/ou emancipação municipal, estabelecendo comparações ao IDHM dos municípios pantaneiros com o IDH brasileiro e dos estados de Mato Grosso (MT) e Mato Grosso do Sul (MS). Selecionou-se os municípios de MT e MS contidos no bioma, agrupados por data de fundação/emancipação em períodos de 50 anos. Os municípios fundados no século XVIII apresentaram os melhores resultados no IDHM (m) e nos indicadores de renda (m) e educação (m). Os emancipados em 1913 a 1963 destacaram-se no de longevidade (m). Os emancipados entre 1811 a 1861 perfizeram os menores valores para o IDHM (m), renda (m), educação (m) e longevidade (m). Os municípios de MT e MS contidos no bioma exibiram resultados inferiores quando comparado aos estados e ao Brasil. A emancipação que não observa a sustentabilidade sócio-estrutural pode resultar na criação de municípios sem as características básicas de manutenção e de suporte ao desenvolvimento humano, a exemplo de Barão de Melgaço e Bodoquena. Concluiu-se que o desenvolvimento humano da fundação/emancipação dos municípios não associaram-se, diretamente, com os períodos de sua criação, ou seja, os mais antigos, de maneira geral, não se sobressaíram aos mais novos, e vice e versa. Ademais, questões como o perfil da gestão e administração pública, políticas públicas, localização geográfica, riquezas naturais, infraestrutura etc., podem contribuir significativamente com os resultados do IDHM tanto positivamente quanto negativamente.
A participação dos países em desenvolvimento e menos desenvolvidos no Órgão de Solução de Controvérsias da Organização Mundial do Comércio
Authors: De Lucena Andréa Freire , De Carvalho Samuel Rufino
Published: October 2018

O Órgão de Solução de Controvérsias da Organização Mundial do Comércio almeja solucionar as disputas comerciais dos países, por meio da supervisão, do monitoramento e da averiguação do cumprimento de suas regras. Um dos entraves do sistema diz respeito às dessemelhanças entre países desenvolvidos e em desenvolvimento. Este artigo investiga a existência de assimetrias de participação entre os países menos desenvolvidos (PMD), países em desenvolvimento (PED) e países desenvolvidos (PD) no âmbito do Órgão de Solução de Controvérsias, desde a sua criação em 1995 até o ano de 2016. Os dados coletados foram trabalhados pelo uso dos métodos estatístico e comparativo, com a intenção de se obter uma análise minuciosa acerca das disputas comerciais e verificar os níveis de desigualdade de atuação na instituição. Observou-se que o Órgão possui assimetrias evidentes de participação, que refletem a divisão internacional do trabalho presente no sistema internacional, em que os Estados de maiores rendas atuam mais facilmente com vistas a suprir suas demandas.
Paradiplomacia como Política Externa e Política Pública: modelo de análise aplicado ao caso da cidade do Rio de Janeiro
Authors: Mercher Leonardo , Pereira Alexsandro Eugenio
Published: October 2018

O presente artigo argumenta que estudos de paradiplomacia devem se aproximar dos estudos de política externa quando investigada como política pública. Essa seria uma estratégia para análise das práticas e estratégias das cidades nas relações internacionais. Os rendimentos analíticos dessa estratégia podem ser observados por meio de um modelo dimensional de análise de paradiplomacia como política externa e política pública. Esse modelo é propostoneste artigo e aplicado ao estudo empírico da cidade do Rio de Janeiro, no período de 1993 até 2016. O modelo sugere cinco dimensões explicativas nas análises da paradiplomacia: gestão política; mercado; institucional; internacional; e epistêmica. A aplicação desse modelo à cidade do Rio de Janeiro permitiu identificar as dimensões mais relevantes no caso específico da cidade — as dimensões política e de mercado —, enquanto que a variável partidária,defendida por outros pesquisadores do campo como de alta capacidade explicativa, pouco interferiu nos resultados observados durante a pesquisa.
O pensamento geoestratégico e os documentos estratégicos dos Estados Unidos no pós Guerra Fria
Authors: Padula Raphael
Published: October 2018

O propósito do artigo é mostrar que há uma conexão entre o pensamento geopolítico clássico anglo-saxão (Mahan, Mackinder e Spykman), as formulações geoestratégicas de Brzezinski e Kissinger durante a Guerra Fria e o pós Guerra Fria, e os documentos estratégicos dos Estados Unidos nesse último período. Essa hipótese é comprovada através da prioridade atribuída à Eurásia (relações Leste-Oeste, no hemisfério Norte), mudando somente a intensidade de atuação em suas diferentes áreas em função da conjuntura histórica. Ao mesmo tempo, não se deixa de atentar para uma geoestratégia permanente de supremacia na América (hemisfério Ocidental). A pesquisa se apoia em bibliografia original dos autores abordados e na análise de documentos estratégicos selecionados de todos os governos estadunidenses na era pós Guerra Fria entre 1991-2016 (Bush a Obama).
An assessment of the operational freeware management tools for multi-reservoir systems
Authors: Rozos Evangelos
Published: October 2018

Water resources management is one of the most challenging problems of the water sector. The complexity of this problem is mostly attributed to the dynamic nature of the natural hydrosystems, of which the inputs are characterized by stochasticity. The assessment of the impact of alternative decisions on such a system requires a probabilistic approach. It is evident that this is a very demanding task even for a single-reservoir system, not to mention multi-reservoir systems. For this reason, computer codes have been developed since the early 1970s to help with this procedure. Nowadays, these codes have evolved into decision support platforms that offer a user interface to assist the pre-processing and the post-processing. However, the majority of the available tools are commercial and require a considerable amount of money for a licence. Thankfully, a few freeware tools that are based on the simulation–optimization method and with a modern user interface exist. The objective of this study is to assess the performance of these freeware tools. The assessment is based both on an analysis of the theoretical basis and on an application of the models on a simplified representation of the Athens water supply system.
Primera época - Año II, Número 4, abril 2000
Authors: El Colegio de San Luis Revista de
Published: October 2018

Este número corresponde a la primera época de la Revista de El Colegio de San Luis, denominado VETAS.
Structural and Molecular Tear Film Changes in Glaucoma
Authors: Mastropasqua Rodolfo , Agnifili Luca , Mastropasqua Leonardo
Published: October 2018

:

The Tear Film (TF) is a trilaminar and dynamic fluid covering the entire Ocular
Surface (OS), consisting of a mucus, aqueous, and lipid layer deeply interacting between
them. Because of its structure and functions, TF plays a pivotal role in the preservation of the
OS integrity and the quality of vision. Medical therapy for glaucoma is recognized to profoundly
disturb the OS homeostasis by altering all components of the ocular surface unit, including
TF. The presence of preservatives, the number of daily eye drops instillations, and the
duration of therapy are the main contributors to TF changes. From the physio-pathological
side, TF alterations are induced by toxic and allergic mechanisms and result from goblet cell
and Meibomian gland loss, dysfunction of accessory lacrimal glands, and epithelial disruption.

:

In detail, TF changes are represented by mucus layer thinning, reduced mucin concentration,
aqueous layer volume reduction, and lipid layer thinning with increased tear evaporation. Hyper-
osmolarity and instability represent the main hallmarks of these changes and are an
expression of a iatrogenic form of dry eye. TF undergoes also molecular modifications that
primarily reflect a therapy- or disease-induced inflammatory status of the OS. Over the last
years, this field of research aimed a progressively growing interest since molecular variations
may be considered as potential candidate biomarkers of glaucoma. The aim of this review is
to report the main TF changes occurring during glaucoma, exploring the relationship they
may have with the glaucoma-related ocular surface disease and the patient quality of life, and
their utility as potential biomarkers of disease.
Torsion of Wandering Spleen: Importance of Splenic Density and Liver-to- Spleen Attenuation Ratio on CT
Authors: Cetinoglu Yusuf Kenan , Karasu Sebnem , Acar Turan , Uluc Muhsin Engin , Haciyanli Mehmet , Tosun Ozgur
Published: October 2018

Background:

Wandering spleen (WS) is a rare clinical condition which may cause fatal
complication like torsion with subsequent infarction. Determination of splenic parenchyma viability
is very important in deciding whether splenopexy rather than splenectomy is an option. Contrast-
enhanced computed tomography (CECT) is important for the diagnosis of WS and assessment
of the viability of spleen.

Discussion:

We reviewed the CT studies of four cases with WS. We measured the mean splenic
and liver density and calculated liver-to-spleen attenuation ratio (LSAR). We also assessed the CT
findings for each patient. Mean splenic density was measured as 40.77 Hounsfield Unit (HU) in
cases with infarction, 127.1 HU in case without infarction. LSAR was calculated as 2.55 in cases
with infarction, 0.99 in case without infarction. We detected whirlpool sign, intraperitoneal free
fluid, splenic arterial enhancement in all patient, parenchymal and splenic vein enhancement in one
patient without infarction, fat rim sign in three patients with infarction, capsular rim sign in one patient
with infarction.

Conclusion:

CECT should be obtained for the diagnosis of WS and assessment of the viability of
spleen. CECT could suggest the diagnosis of infarction of the spleen with following findings; absence
of parenchymal enhancement, very low density of spleen (<45 HU), and LSAR which is
greater than 2.
El laboratorio como herramienta didáctica aplicada al estudio de sistemas dispersos groseros. Clase práctica sobre el magma de hidróxido de magnesio
Authors: Perez Ana Raquel
Published: October 2018

En este trabajo se describen experimentos de laboratorio sobre una preparación muy usual en farmacia oficinal: el magma de hidróxido de magnesio (MHM), también conocido como leche de magnesia. Su ejecución permite al alumno caracterizar las variables relevantes para la estabilidad de sistemas dispersos groseros (SDG), con el fin de determinar el tipo de SDG, la concentración óptima de electrolito que produce la máxima floculación y la naturaleza del ión floculante responsable del fenómeno. El objetivo de esta práctica es que el alumno adquiera los conocimientos necesarios y las habilidades útiles para el diseño, desarrollo y caracterización de suspensiones de uso común en farmacia.