bluuebunny/crossref_metadata_2025 huggingface dataset:
Regulate PD-L1's membrane orientation thermodynamics with hydrophobic nanoparticles
Authors: Lin Xiaoqian , Lin Xubo
Published: December 2024

Embedded hydrophobic NPs promote PD-L1's transition from a “lie down” (L) state to a “stand up” (S) state.
Biaxially chiral compounds: research and development of synthesis
Authors: Feng Kongling , Yao Chaochao , Xu Hao
Published: December 2024

To date, two asymmetric catalytic methods have been established for the synthesis of biaxially chiral molecules: transition-metal-catalysis and asymmetric organocatalysis.
Methanesulfonic acid (MSA) and SO3 formation from the addition channel of atmospheric dimethyl sulfide oxidation
Authors: Berndt Torsten
Published: December 2024

CH3SO3 radicals represent the key intermediate for the formation of methanesulfonic acid (MSA) and SO3 from the addition channel of dimethyl sulfide (DMS) oxidation in the atmosphere. HO2 radicals are not a main H-atom donor for MSA production.
Enhancing activity and selectivity of palladium catalysts in ketone α-arylation by tailoring the imine chelate of pyridinium amidate (PYA) ligands
Authors: Reusser Esaïe , Aeschlimann Michael , Albrecht Martin
Published: December 2024

Palladium complexes with chelating pyridinium amidate ligands are efficient catalysts for the α-arylation of ketones. Their catalytic activity depends on the chelating group at the PYA, with iPr-substituted pyrazole PYAs reaching high turnover frequencies.
Hybrid-LLM-GNN: integrating large language models and graph neural networks for enhanced materials property prediction
Authors: Li Youjia , Gupta Vishu , Kilic Muhammed Nur Talha , Choudhary Kamal , Wines Daniel , Liao Wei-keng , Choudhary Alok , Agrawal Ankit
Published: December 2024

This study combines Graph Neural Networks (GNNs) and Large Language Models (LLMs) to improve material property predictions. By leveraging both embeddings, this hybrid approach achieves up to a 25% improvement over GNN-only model in accuracy.
Rational side-by-side self-assembly of gold nanorods with short and medium aspect ratios via the self-evaporation method to boost their potential as a surface-enhanced Raman scattering (SERS) substrate
Authors: Vo Khuong Quoc , Huynh Thanh-Tuyen Thi , Nguyen Thu Anh , Truong Tan-Trung
Published: December 2024

A facile approach for the perpendicular and parallel arrangements of gold nanorods on a silicon substrate is essential for enhancing the electromagnetic field intensity of SERS substrates.
Unravelling the in vivo biotoxicity of a green-biofabricated graphene oxide–microplastic hybrid mediated by proximal intrinsic atomic interactions
Authors: Sinha Adrija , Lenka Sudakshya S. , Gupta Abha , Singh Dibyangshee , Choudhury Anmol , Naser Shaikh Sheeran , Ghosh Aishee , Simnani Faizan Zarreen , Nandi Aditya , Mishra Richa , Verma Suresh K. , Suar Mrutyunjay
Published: December 2024

GO@PS exhibit higher biotoxicity than individual graphene oxide and polystyrene primarily through oxidative stress in zebrafish embryos emphasizing the environmental and health risks.
EES Catalysis: embracing energy and environmental catalysis
Authors: Qiao Shi-Zhang
Published: December 2024

Editor-in-Chief, Shizhang Qiao, reflects on the second year of EES Catalysis and looks ahead to 2025.
Broccoli (Brassica oleracea L. var. italica Planch) alleviates metabolic-associated fatty liver disease through regulating gut flora and lipid metabolism via the FXR/LXR signaling pathway
Authors: Lu Yingjian , Li Xin , Ma Shaotong , Ding Meng , Yang Feiyu , Pang Xinyi , Sun Jing , Li Xiangfei
Published: December 2024

The increased consumption of dietary fats contributes to the development of MAFLD (metabolic fatty liver disease).
Lactobacillus rhamnosus LC-STH-13 ameliorates the progression of SLE in MRL/lpr mice by inhibiting the TLR9/NF-κB signaling pathway
Authors: Liao Wen , Zhang Xinyi , Jia Chunjian , Chen Wenjing , Cai Yujie , Zhang Hongyan , Wei Jing , Chen Tingtao
Published: December 2024

Lactobacillus rhamnosus LC-STH-13 ameliorates the progression of SLE in MRL/lpr mice by modulating the gut microbiota and inhibiting the TLR9/NF-κB signaling pathway.
Antihypertensive effects of rice peptides involve intestinal microbiome alterations and intestinal inflammation alleviation in spontaneously hypertensive rats
Authors: Li Juan , Wei Wei , Ma Xiaomin , Ji Jing , Ling Xiaomeng , Xu Zhuyan , Guan Yutong , Zhou Leyan , Wu Qiming , Huang Wenhua , Liu Fuguo , Zhao Min
Published: December 2024

Schematic diagram describing the proposed pathway for the effects of rice peptides on spontaneous hypertension.
Solvent-free preparation of propionyl-modified pulp fibers for high-density polyethylene reinforcement
Authors: Zhang Shuya , Zhao Yixin , Che Mingda , Huang Renliang , Cui Mei , Qi Wei , Su Rongxin
Published: December 2024

We report a solvent-free approach for the production of high-density polyethylene reinforced with propionic anhydride-modified fibers (HDPE/PAF). By recycling the reagents, the production cost of HDPE/PAF was reduced by 65.50%.
Stretchable impedance electrode array with high durability for monitoring of cells under mechanical and chemical stimulations
Authors: Kim A Ri , Hong Seok Ju , Lee Han-Byeol , Lee Nae-Eung
Published: December 2024

Electrochemical impedance spectroscopy (EIS) serves as a non-invasive technique for assessing cell status, while mechanical stretching plays a pivotal role in stimulating cells to emulate their natural environment.
A FET-based flexible biosensor system for dynamic behavior observation of lipid membrane with nanoparticles in vitro
Authors: Zhu Keyi , Lu Hanjing , Xue Qiannan , Zhou Feng , Guo Wenlan , Sun Chen , Duan Xuexin
Published: December 2024

An in vitro FET-based flexible biosensor system to study the interactions between nanoparticles and cell membranes under active conditions is proposed; this system can be applied to various research areas, such as the toxicology or pharmacology.
3D-printed acoustic metasurface with encapsulated micro-air-bubbles for frequency-selective manipulation
Authors: Ji Miaomiao , Liu Yukai , Zhang Zheng , Xu Rui , Pan Fanyun , Zhang Ya , Su Rouyu , Lu Minghui , Zhang Xiujuan , Wang Guanghui
Published: December 2024

A low-frequency acoustic metasurface with PDMS-stabilized microbubbles achieves stable vibration modes, precise control over micro-object aggregation, rotation, separation, and selective trajectory manipulation through frequency-tuned excitation.
Mn-substitution effects on the magnetic and zero-field ferromagnetic resonance properties of ε-Fe2O3 nanoparticles
Authors: MacDougall Jessica , Namai Asuka , Strolka Onno , Ohkoshi Shin-ichi
Published: December 2024

Mn-substituted ε-Fe2O3 (ε-MnxFe2−xO3−x/2) nanomagnets show increased coercive field and zero-field ferromagnetic resonance frequency with higher Mn content.
Supramolecular ionogels enable highly efficient electrochromism
Authors: Zhou Kaijian , Tang Liang , Kuang Guoqiang , Zhang Jun , Li Zhiyong , Xing Guoqiang , Jiang Xueao , Chen Zhanying , Tao Yijie , Zhang Yan , Zhang Shiguo
Published: December 2024

Supramolecular ionogels served as gel electrolytes for electrochromic devices using electrochromic polymers or viologen derivatives, exhibiting performance comparable to ionic liquid electrolytes and superior to polymer gelator-based ionogels.
Cyanocarbazole-based bipolar host materials for efficient phosphorescent and thermally activated delayed fluorescence OLEDs
Authors: Tao Yeting , Zhang Yaotian , Hu Shiying , Wang Jian , Wu Yuying , Yuan Wenbo , Yao Wei , Tao Youtian
Published: December 2024

Bipolar host material o-4CN-TRZ with cyano substitution at the 4-position of carbazole exhibited higher efficiency than o-3CN-TRZ in both phosphorescence and TADF OLEDs.
Neutral self-assembly of dinuclear copper(ii) metallacycles derived from Schiff base ligands: synthesis, characterization and catalysis
Authors: Jain Isha , Rohini  , Jain Ravish Kumar , Devi Sudha , Malik Payal
Published: December 2024

The synthesis and characterization of neutral dinuclear copper(ii) metallacycles are discussed and their photophysical, magnetic and catalytic properties are investigated.
Synthesis of a hydrogel from a combination of cellulose Gracilaria verrucosa and carboxymethyl sago starch using freeze-drying and oven-drying methods as a commercial textile dye adsorbent
Authors: Tuljannah Nudia , Sondari Dewi , Amanda Putri , Hanifah Arzqa Sabila , Ahmad Ahyar , Karim Harningsih
Published: December 2024

This study aimed to develop a hydrogel adsorbent capable of absorbing dyes from textile industry waste.
Rb-promoted Fe/CeO2 nanocatalyst for aniline conversion into azoxybenzene, DFT calculations and mechanism
Authors: Khan Afsar , Xiao Sa , Xie Yu , Kaya Savaş , Zareen Shah , Muhammad Nisar , Parveen Kousar , Xu Dayong
Published: December 2024

Selectivity control of aniline oxidation and low reactant conversion in traditional synthesis methods are great challenges, and it is desirable to develop a green, low-cost and highly efficient catalytic route toward value-added products.
Controlled growth of oriented porous hexagonal ZnO nanosheets on nitinol fibre as superior coatings in solid-phase microextraction coupled to HPLC-UV for preconcentration and determination of polycyclic aromatic hydrocarbons in water
Authors: Zhou Hua , Liu Haixia , Qin Nian , Ke Jianlan , Wang Xuemei , Du Xinzhen
Published: December 2024

Oriented porous hexagonal ZnO nanosheets were grown on a nitinol (NiTi) fiber substrate as a superior fiber in SPME coupled to HPLC-UV for the enrichment and determination of trace PAHs in water samples.
Rational design of d-glucose derived nitrogen-doped hierarchical porous activated carbon: an ultra-performance cathode for zinc-ion hybrid supercapacitors
Authors: Sarathkumar Sankar , Yuvaraja Raji , Gowsalya Venkatesan , Anitha Juliet Sorna Pandian , Veeralakshmi Selvakumar , Nehru Selvan
Published: December 2024

Optimally prepared N-doped hierarchical porous activated carbon from d-glucose and urea at 700 °C shows enhanced specific capacitance, energy density, and appreciable cycling stability as a cathode material in Zn-ion hybrid supercapacitors.
Investigation of Ti nanostructures via laboratory scanning-free GEXRF
Authors: Staeck Steffen , Baumann Jonas , Hönicke Philipp , Wauschkuhn Nils , Spikermann Ferdinand , Grötzsch Daniel , Stiel Holger , Kanngießer Birgit
Published: December 2024

Laboratory scanning-free GEXRF in the tender X-ray range is utilized to investigate a Ti nanograting. For the first time, a reconstruction of a periodic 2D nanosample is presented based on laboratory measurements.
Injectable sustained-release hydrogel for high-concentration antibody delivery
Authors: Zheng Talia , Doyle Patrick S.
Published: December 2024

Highly concentrated solid antibodies are formulated in an injectable dual-network composite hydrogel for sustained-release delivery.
One-step preparation of anisotropic snowman-like poly(ionic liquid) microspheres via microwave-assisted dispersion polymerization
Authors: Hu Xufeng , Li Jingyi , Zhao Xiaopeng , Yin Jianbo
Published: December 2024

We reported a one-step microwave-assisted dispersion polymerization method to prepare snowman-like PIL microspheres whose morphology can be adjusted by the amounts of monomer, DVB, initiator, solvent and microwave radiation temperature and mode.
The Shastry–Sutherland lattice in two-dimensional magnetic lanthanide metal–organic frameworks
Authors: Li Jing , Sun Xiao , Chen Peiqiong , Huang Ruiqin , Zeng Suyuan , Liu Hou-Ting , Han Yibo , Zhang Yi-Quan , Tian Haiquan
Published: December 2024

A detailed study on the relaxation dynamics of the SS lattice, using a targeted orthogonal-dimer dissolution–crystallization strategy, has shown this method to be highly effective for developing novel 2D lanthanide compounds for magnetic studies.
Theoretical design and experimental realization of Fe3+-doped dual-band near-infrared garnet phosphors
Authors: Wang Yutong , Chen Anfei , Jiang Sha , Zhong Lei , Li Li , Zhou Xianju , Duan Chang-Kui , Chen Qiaoling
Published: December 2024

Dual-band near-infrared luminescence in Fe3+-doped garnets successfully implemented experimentally based on theoretical design.
A tandem nanoreactor constructed by coating Cu2O on the surface of single-atom catalyst Ni-NC3 for electroreduction of CO2 to C2 products
Authors: Liang Cheng-Peng , Huang Jia-Run , Liao Pei-Qin , Chen Xiao-Ming
Published: December 2024

A tandem nanoreactor constructed by coating Cu2O on the surface of single-atom catalyst Ni-NC3 for electroreduction of CO2 to C2 products.
Stimuli-responsive gold–polyoxometalate multielectron transformers
Authors: Monakhov Kirill
Published: December 2024

Gold-polyoxometalate hybrid materials promise a positive impact on various application areas, from unsolved diagnostic problems to increasing electron storage capacity.
Acetic acid-catalyzed synthesis of 1,5-disubstituted 1,2,3-triazoles under azide-free conditions
Authors: Li Jiuling , Jia Xinyu , Yang Qiangguo , Guo Jiakang , Ren Qianhui , Liu Taichen , Wei Kai , Kang Zhenghui
Published: December 2024

An environmentally-friendly and safe method has been developed to synthesize 1,5-disubstituted 1,2,3-triazoles containing difluoromethyl fragments, which can be obtained from readily available 2,2-difluoroarylethylamines under azide-free conditions.
Solvent-controlled C2/C3-regioselective ring-opening/coupling of aziridines with amines and CS2: synthesis of 2-aminoethyl dithiocarbamates
Authors: Li Wenxue , Yang Xueying , Miao Man , Sun Fengkai , Yuan Hui , Lan Xiao-Bing , Yu Jian-Qiang , Zhang Jian , An Zhenyu
Published: December 2024

A solvent-controlled C2/C3-regioselective ring-opening/coupling strategy was developed to synthesize two types of 2-aminoethyl dithiocarbamates from aziridines, amines, and CS2.
Blue light-activated 5,10,15,20-tetrakis(4-bromophenyl)porphyrin for photodynamic eradication of drug-resistant Staphylococcus aureus
Authors: Qin Hongshuang , Niu Huaying , Guo Yanxiang , Wang Xiaoting , Liu Tao , Zhao Chuanqi
Published: December 2024

Photodynamic therapy mediated by 5,10,15,20-tetrakis(4-bromophenyl)porphyrin (TBPP) effectively eliminates drug-resistant Staphylococcus aureus, inhibits biofilm formation and accelerates wound healing in a mouse model.
Enabling amidation in water: micellar catalysis approach for sustainable synthesis of iopamidol
Authors: Zucchi Anita , Mattiello Sara , Maschio Rachele , Bellotti Valentina , Giovenzana Giovanni B. , Lattuada Luciano , Beverina Luca
Published: December 2024

Micellar catalysis is becoming an increasingly versatile tool to carry out a wide range of organic transformations using water as the reaction medium.
On the redox mechanism of methanol carbonylation on a dispersed ReOx/SiO2 catalyst
Authors: Tran Neil D. , Mironenko Alexander V.
Published: December 2024

Methanol carbonylation on –ORe(O)3 sites is studied via DFT and NBO. Re(vii) reduction is required for activation. While C–C coupling is facile, C–O activation is challenging on monopodal site, suggesting a different form of catalyst's structure.
Aromatic–aromatic interactions drive fold switch of GA95 and GB95 with three residue difference
Authors: Chen Chen , Zhang Zeting , Duan Mojie , Wu Qiong , Yang Minghui , Jiang Ling , Liu Maili , Li Conggang
Published: December 2024

This study reveals that aromatic interactions at F52 are crucial for protein fold switching in GA95 and GB95. The aromatic cluster involving Y45 in GB95 further facilitates this transition, highlighting the cooperative role of three mutation sites.
Buried interface management toward high-performance perovskite solar cells
Authors: Du Bin , Lin Yuexin , Ma Jintao , Gu Weidan , Liu Fei , Yao Yijun , Song Lin
Published: December 2024

The interface between the perovskite layer and the electron transport layer is an extremely important factor that cannot be ignored in achieving high-performance perovskite photovoltaic technology.
Regulation of swelling behaviour while preserving bulk modulus in hydrogels via surface grafting
Authors: Nishimoto Taihei , Akimoto Aya M. , Enomoto Takafumi , Lin Chia-Hsuan , Luo Shy-Chyang , Yoshida Ryo
Published: December 2024

In this study, we systematically controlled the swelling behavior of the gel without affecting the bulk elastic modulus by grafting polymers into the surface region of the gel only while systematically varying the density.
Quantification of mobile charge carrier yield and transport lengths in ultrathin film light-trapping ZnFe2O4 photoanodes
Authors: Miriyala Kumaraswamy , Shor Peled Sa'ar , Klotz Dino , Grave Daniel A.
Published: December 2024

Resonant light trapping is used to enhance the performance of Ti-doped ZnFe2O4 (ZFO) photoanodes. Spatial collection efficiency analysis shows that non-unity photogeneration yield of mobile charge carriers limits the performance of ZFO.
Capacity-weighted figures-of-merit for battery transport metrics
Authors: Sturgill CJ , Sutton Christopher , Schwenzel Julian , Stefik Morgan
Published: December 2024

Fast-charging materials are necessary for a battery-centric future. Ionic and electronic transport crucially determine performance where their capacity-weighted figures-of-merit account for performance across all states-of-charge.
Perfluoroalkyl-functionalization of zirconium-based metal–organic framework nanosheets for photosynthesis of hydrogen peroxide from dioxygen and water
Authors: Kondo Yoshifumi , Mizutani Shiori , Kuwahara Yasutaka , Mori Kohsuke , Sekino Tohru , Yamashita Hiromi
Published: December 2024

Hydrophobization of Zr-based MOF nanosheets using perfluoroalkyl carboxylates dramatically promotes photocatalytic hydrogen peroxide production from dioxygen and water.
Plant-derived exosome-like nanoparticles in tissue repair and regeneration
Authors: Gao Canyu , Chen Yang , Wen Xingyue , Han Ruiying , Qin Yuxiang , Li Sijie , Tang Rong , Zhou Weikai , Zhao Junyu , Sun Jianxun , Li Zhengyong , Tan Zhen , Wang Deli , Zhou Changchun
Published: December 2024

This article reviews the extraction and characterization of ELNs, discussing their structure-function relationship. It examines recent advances in ELNs for tissue regeneration and highlights challenges and future directions in tissue repair and regeneration.
Design, synthesis, and characterization of an Ag–Bi–S-based multifunctional nanotheranostic platform
Authors: Tan Yuan-Yi , Chen Xin , Zheng Dong-Yun , Liu Chao , Liu Xiao-Jun , Lin Xian-Guang , Zhu Chun-Nan
Published: December 2024

The optimized Ag–Bi–S-based nanotheranostic platform was demonstrated to be Ag2S/Bi2S3 core/shell nanocrystals, exhibiting bright NIR-II fluorescence, good CT imaging contrast, and a significant photothermal effect.
Antibonding Cu (d)–Te (p) states and bonding inhomogeneity in inducing low lattice thermal conductivity and extraordinary thermoelectric properties of the layered heteroanionic NdCuOTe material: a first-principles study
Authors: Tang Shuwei , Guo Wanrong , Wan Da , Li Xiaodong , Zheng Tuo , Wang Hao , Li Qingshun , Qi Xiuling , Bai Shulin
Published: December 2024

Layered NdCuOTe material exhibits excellent thermoelectric properties on account of the bonding inhomogeneity, antibonding state, and band degeneracy.
Structural commonalities determined by physicochemical principles in the complex polymorphism of the amyloid state of proteins
Authors: Errico Silvia , Fani Giulia , Ventura Salvador , Schymkowitz Joost , Rousseau Frederic , Trovato Antonio , Vendruscolo Michele , Bemporad Francesco , Chiti Fabrizio
Published: December 2024

Advances in solid-state nuclear magnetic resonance (ssNMR) spectroscopy and cryogenic electron microscopy (cryoEM) have revealed the polymorphic nature of the amyloid state of proteins. Given the association of amyloid with protein misfolding disorders, it is important to understand the principles underlying this polymorphism. To address this problem, we combined computational tools to predict the specific regions of the sequence forming the β-spine of amyloid fibrils with the availability of 30, 83 and 24 amyloid structures deposited in the Protein Data Bank (PDB) and Amyloid Atlas (AAt) for the amyloid β (Aβ) peptide, α-synuclein (αS), and the 4R isoforms of tau, associated with Alzheimer’s disease, Parkinson’s disease, and various tauopathies, respectively. This approach enabled a statistical analysis of sequences forming β-sheet regions in amyloid polymorphs. We computed for any given sequence residue n the fraction of PDB/AAt structures in which that residue adopts a β-sheet conformation (Fβ(n)) to generate an experimental, structure-based profile of Fβ(n) vs n, which represents the β-conformational preference of any residue in the amyloid state. The peaks in the respective Fβ(n) profiles of the three proteins, corresponding to sequence regions adopting more frequently the β-sheet structural core in the various fibrillar structures, align very well with the peaks identified with five predictive algorithms (ZYGGREGATOR, TANGO, PASTA, AGGRESCAN, and WALTZ). These results indicate that, despite amyloid polymorphism, sequence regions most often forming the structural core of amyloid have high hydrophobicity, high intrinsic β-sheet propensity and low electrostatic charge across the sequence, as rationalised and predicted by the algorithms.
“1-800-Help-Me-With-Open-Science-Stuff”: A Qualitative Examination of Open Science Practices in Communication Sciences and Disorders
Authors: Pfeiffer Danika L. , Thompson Austin , Ciullo Brittany , Hirsch Micah E. , El Amin Mariam , Ford Andrea , Riccardi Jessica , Kearney Elaine
Published: December 2024

Purpose:

The purpose of this qualitative study was to examine the perceptions of communication sciences and disorders (CSD) assistant professors in the United States related to barriers and facilitators to engaging in open science practices and identify opportunities for improving open science training and support in the field.

Method:

Thirty-five assistant professors (16 from very high research activity [R1] institutions, 19 from institutions with other Carnegie classifications) participated in one 1-hr virtual focus group conducted via Zoom recording technology. The researchers used a conventional content analysis approach to analyze the focus group data and develop categories from the discussions.

Results:

Five categories were developed from the focus groups: (a) a desire to learn about open science through opportunities for independent learning and learning with peers; (b) perceived benefits of engaging in open science on assistant professors' careers, the broader scientific community, and the quality of research in the field of CSD; (c) personal factors that act as barriers and/or facilitators to engaging in open science practices; (d) systemic factors that act as barriers and/or facilitators to engaging in open science practices; and (e) differences in perceptions of R1 and non-R1 assistant professors.

Conclusions:

Assistant professors in CSD perceive benefits of open science for their careers, the scientific community, and the field. However, they face many barriers (e.g., time, lack of knowledge and training), which impede their engagement in open science practices. Preliminary recommendations for CSD assistant professors, academic institutions, publishers, and funding agencies are provided to reduce barriers to engagement in open science practices.

Supplemental Material and Open Science Form:

https://doi.org/10.23641/asha.27996839
Sentence Comprehension in Spanish-Speaking Children With Hearing Loss: On the Integration of Morphosyntactic and Lexico-Semantic Cues
Authors: Taboh Analí Rosa , Shalom Diego Edgar , Alvares Belén , Gattei Carolina Andrea
Published: December 2024

Purpose:

Children with hearing loss (CHL) who use hearing devices (cochlear implants or hearing aids) and communicate orally have trouble comprehending sentences with noncanonical order. This study explores sentence comprehension strategies in Spanish-speaking CHL, focusing on their ability to integrate morphosyntactic cues (word order, morphological case marking) with verbs differing in their syntax-to-semantics configuration.

Method:

Fifty-eight Spanish-speaking CHL and 58 children with typical hearing (CTH) with a hearing age of 3;5–7;8 (years;months; i.e., time of adequate access to sound, in the case of CHL since effective fitting or implantation) were recruited in Argentina. A sentence comprehension task using the truth-value judgment paradigm was designed, including sentences with activity verbs and object-experiencer psych verbs in subject–verb–object (SVO) and object–verb–subject (OVS) orders, thus varying in canonicity.

Results:

Both groups showed good comprehension of SVO sentences with activity verbs but had difficulties with structures that deviated from canonicity. Comprehension was at chance level in both groups and at all hearing ages for sentences with activity verbs in OVS order and sentences with object-experiencer psych verbs in SVO order (both are noncanonical for the verb type). Sentences with object-experiencer psych verbs in OVS order were also comprehended at chance level by CHL and by the youngest CTH.

Conclusions:

These results suggest that Spanish-speaking CTH aged 7 years prioritize semantic information over case marking in sentences with a noncanonical syntactic structure. In CHL, difficulties with noncanonical structures seem to extend to semantic deviations, at least until hearing age 7 years. CHL might also struggle with the semantic structures of object-experiencer psych verbs beyond the age when CTH do. These findings are relevant for the linguistic assessment and education of CHL.
Exploring Self-Reported Quality of Life in Developmental Language Disorder
Authors: Larson Caroline
Published: December 2024

Purpose:

Developmental language disorder (DLD) is a lifelong condition associated with poorer outcomes than neurotypical peers, yet relatively little is known about long-term quality of life in DLD. This preliminary study adopts a neurodiversity-informed approach by exploring
self-reported
quality of life in an adolescent and young adult DLD sample, as well as linguistic and risk factors contributing to quality of life.

Method:

Participants were five individuals with DLD aged 12–20 years (
M
= 15.60,
SD
= 3.05). I administered two self-report quality-of-life scales, a language assessment, an experimental morphosyntax task, and measures of risk factors. Data were analyzed descriptively.

Results:

Participants generally reported positive views about their quality of life, although accessing accommodations and health services emerged as barriers. Relatively better grammaticality judgment performance appeared to be linked with poorer ratings of happiness and the ability to “be yourself.” Nonverbal ability represented a potential risk factor, although there may be a stronger cumulative role for risk factors.

Conclusions:

Participants with DLD reported relatively good quality of life. Exploratory findings suggest barriers to quality of life in some contexts, as well as roles for individual differences in language and risk factors. These descriptive findings should be examined in larger scale studies and may represent areas of consideration when clinicians address functional challenges that impact mental health and well-being in individuals with DLD.

Supplemental Material:

https://doi.org/10.23641/asha.27997529
Study of bistability and hyperchaos in a coupled class‐B laser system
Authors: Yan Senlin
Published: December 2024

A coupled class‐B laser system is presented to obtain a nonlinear emitter. Its bistability was theoretically predicted, and numerically illustrated to demonstrate by a typical bistable curve diagram. The bistable system exhibits some typical nonlinear dynamic behaviours, such as hyperchaos, quasi‐period as well as coexistent scenarios, and shows a route to a single‐period away from hyperchaos. The hyperchaotic states are diagnosed to find by Lyapunov exponent. The hyperchaotic four‐scroll strange attractor was illustrated to be characterized by ergodicity, complexity, and randomness. The result has a reference value for a bistable optical device, a hyperchaotic emitter, and their applications.
A unified multi‐class anomaly detection model based on reverse distillation
Authors: Fu Maoli , Fu Zhongliang
Published: December 2024

The multi‐class single‐model detection paradigm is a prevalent design for industrial anomaly detection, exhibiting suitability for varying industrial classes and dynamic, flexible production scenarios. This approach not only enhances model adaptability but also minimizes maintenance costs. However, the current popular methods are susceptible to the ‘copying shortcut’ phenomenon, which constrains their performance on benchmark datasets. To overcome this limitation, this article proposes a multi‐class anomaly detection model: UniRD, based on the reverse distillation method. This model creates an image corruptor that expands the dataset and generates ‘normal‐corrupt’ image pairs. During the training process, their correspondence is used to optimize the reverse distillation. This process greatly exploits and releases the potential of the student decoder. Furthermore, a teacher feature adaptation module is devised to enhance the compatibility between the pre‐trained model and the anomaly detection task. This has the effect of reducing the discrepancy between teacher and student features while ensuring the consistency of normal sample features. The comprehensive evaluation results in two mainstream datasets, MVTec and VisA, and demonstrates that the proposed method exhibits improvement in all indicators compared to benchmark methods. The proposed method attains the state‐of‐the‐art, substantiating its effectiveness and advancement.
Asteroid detection polar equation calculation and graphical representation
Authors: Cano J. L. , Micheli M. , Ramírez-Moreta P. , Hoffmann T. , Conversi L. , Fenucci M. , Oliviero D. , Ocaña F.
Published: December 2024

Context. The observability of an asteroid from the ground depends on the distance to the Sun and the observer, on the phase angle, on the object shape, and on its surface reflectivity properties. Several magnitude systems have been proposed in the past decades to model the visual magnitude of the object based on these parameters.

Aims. Independently of the magnitude system, there is a three-dimensional representation of the geometrical locus of equal visual magnitude when this value is constrained for a given asteroid. We called this the detection polar curve, or just, the detection polar. We derived a process in order to represent it graphically.

Methods. We analysed the shape of this geometrical locus for the H, G magnitude system and determined its applicability to the representation of the detectability of an asteroid in its trajectory. We thus calculated the asteroid detection polar equation, as well as the threshold values that change the type of asteroid detectability solution.

Results. The resulting detection polar is discussed, the synodic orbit visualisation tool is introduced, as are examples of how it can be used to analyse the graphical representation of an asteroid trajectory, and to represent the detection polar for a given limiting visual magnitude.
Searching for star-planet interactions in GJ 486 at radio wavelengths with the uGMRT
Authors: Peña-Moñino L. , Pérez-Torres M. , Kansabanik D. , Blázquez-Calero G. , Kavanagh R. D. , Gómez J. F. , Moldón J. , Alberdi A. , Amado P. J. , Anglada G. , Caballero J. A. , Mohan A. , Leto P. , Narang M. , Osorio M. , Revilla D. , Trigilio C.
Published: December 2024

Aims. We search for radio emission from star–planet interactions in the M dwarf system GJ 486, which hosts an Earth-like planet.

Methods. We observed the GJ 486 system with the upgraded Giant Metrewave Radio Telescope (uGMRT) from 550 to 750 MHz in nine different epochs between October 2021 and February 2022, covering almost all orbital phases of GJ 486b from different orbital cycles. We obtained radio images and dynamic spectra of the total and circularly polarized intensity for each individual epoch.

Results. We did not detect any quiescent radio emission in any epoch above 3σ. Similarly, we did not detect any bursty emission in our dynamic spectra.

Conclusions. While we cannot completely rule out that the absence of a radio detection is due to time variability of the radio emission or to the maximum electron-cyclotron maser emission being below our observing range, these cases seem unlikely. We discuss two possible scenarios: an intrinsic dim radio signal and, alternatively, a situation where the anisotropic beamed emission is pointed away from the observer. If the non-detection of radio emission from the star-planet interaction in GJ 486 is due to an intrinsically dim signal, this implies that independent of whether the planet is magnetized or not, the mass-loss rate is small (Ṁ⋆ ≲ 0.3 Ṁ⊙) and that, concomitantly, the efficiency of the conversion of the Poynting flux into radio emission must be low (β ≲ 10−3). Free-free absorption effects are negligible, given the high value of the coronal temperature. Finally, if the anisotropic beaming pointed away from the observer, this would imply that GJ 486 has very low values of magnetic obliquity and inclination.
Towards an update of the ILD ZHH analysis
Authors: Bliewert Bryan , Vernieri Caterina , Ntounis Dimitris , List Jenny , Torndal Julie Munch , Tian Junping
Published: December 2024

The double Higgs-strahlungs process e+e− → ZHH allows to access the Higgs self-coupling at center-of-mass energies above 450 GeV. Its cross-section exhibits a very different behavior as a function of the value of the self-coupling than fusion-type processes like gluon-gluon fusion at LHC (and future hadron colliders) and WW / ZZ fusion at higher energy lepton colliders. Therefore it adds unique information to the picture, in particular should the value of the Higgs self-coupling differ from its Standard Model prediction. The last full evaluation of the potential of the ILC to measure this process is more than ten years old, and since then many of the reconstruction tools have received very significant improvements. This contribution presents the ongoing work in the ILD collaboration to update the ZHH projections for the next European Particle Physics Strategy Update.
X-LAB: A very high-capacity X-band RF test stand facility at the University of Melbourne
Authors: Volpi Matteo , Giansiracusa Paul J. , Sheehy Suzanne L. , Rassoll Roger P. , Taylor Geoffrey N. , Pushkarna Paarangat , Dowd Rohan , Valerian Joel , Catalan-Lasheras Nuria , Cherrill Mark
Published: December 2024

The X-band Laboratory for Accelerators and Beams (X-LAB) has been commissioned at the University of Melbourne. One of the key projects within this laboratory involves re-homing half of the CERN high gradient X-band test stand, XBOX3, now known as Mel-BOX. This initiative aims to validate the performance of high-gradient travelling wave accelerating structures operating at a frequency of 12 GHz, which are a crucial component of the acceleration baseline for the Compact Linear Collider (CLIC). Mel-BOX will be employed to assess the performance of these accelerating structures under high power pulsed RF. As with XBOX3, Mel-BOX uses the combined power from two high average power klystron units to feed two test slots at a repetition rate of up to 400 Hz. Additionally, the parameters such as repetition rate, peak power, pulse length, and pulse shape can be tailored to meet specific test requirements. This method of generating high-power, high-repetition RF pulses holds promise for various applications necessitating multiple test slots. Moreover, there are plans to leverage this technology as a foundation for developing compact accelerators tailored for medical or university applications, including radiotherapy and compact light sources.
The LISA project: opportunities and challenges of recycling automotive heat exchangers
Authors: Lattanzi Lucia , Liljenfors Tomas , Westergård Richard , Windmark Christina
Published: December 2024

A modern vehicle typically has up to ten different heat exchangers, ensuring prolonged technology life, improved performance, and passenger comfort. Heat exchangers for automotive applications are made of multilayer-clad brazed aluminium. They are mature products, having been used in passenger and commercial internal combustion engine vehicles for decades, and their use will continue in electrified vehicles to cool batteries, power electronics and other components that exchange heat with the environment. With the increased awareness of the industrial impact on sustainability and commitment to scientific-based targets, the push for circularity drives the need for economically viable solutions to recycle the multilayered materials in automotive heat exchangers. The project’s final goal is to identify the value chain’s sustainability, cost-improvement potential, and business opportunities to minimise material degradation and value losses. This work presents the research methods used in the project to approach the last two steps of the value chain. The results of the laboratory-scale remelting experiments are promising and indicate the possibility of recycling heat exchangers to produce new ones, keeping the material within the same value chain and limiting the material value losses. There is also an increased drive for cost calculations in products, and the foundations of a techno-economic model are being developed to assess the outcome of future recycling operations.
Development of clump-on sonar flow meter using symmetry channel model
Authors: Krivonogov Aleksei , Taranenko Pavel Alexandrovich , Khan Afrasyab
Published: December 2024

In connection to methods developed for determining of “liquid–gas” volume-mass parameters, research has been carried out by a group of scientists from South Ural State University and University of Dundee, where the current manuscript presents a new method for measuring a liquid and gas flow rate. Method able to measure a turbulent flow convective velocity through the pipeline wall and volumetric flow rate of a liquid and gas. A brief description of G. Taylor's “frozen turbulence” hypothesis is given on the basis of which the method works. Main scientific problems associated with its proof in relation to the problem of determining the convection velocity of turbulence are identified. Mathematical modeling was performed in the CFD computational fluid dynamics package using the hybrid eddy-resolving turbulence model SBES to determine an optimal configuration of the experimental setup. This model contains 2-D symmetry domain to decries simulation time. In this article describe correlation between 2-D symmetry model and full-scale tests. Result of experimental tests are presented. Therefore, novelty of this investigation is noninvasive method for flow measurement and experimental confirmation that it works.
Portal vein velocity and its dynamics: a potentially useful tool for detecting clinically silent transjugular intrahepatic porto-systemic shunt dysfunction using Doppler ultrasonography
Authors: Spârchez Zeno , Procopeţ Bogdan , Crăciun Rareș , Ștefănescu Horia , Nicoară-Farcău Oana , Fischer Petra , Fodor Andreea , Tanţău Marcel , Radu Corina
Published: December 2024

Background  Ultrasound (US) surveillance for transjugular intrahepatic portosystemic shunt (TIPS) dysfunction has yet to be standardized, as clear-cut criteria have not been conventionally defined. This study evaluated the role of US-based parameters in detecting hemodynamic TIPS dysfunction (HD).

Methods  We included consecutive patients treated with TIPS. All patients were scheduled within the first six weeks after the procedure for TIPS revision, comprised of a Doppler US exam and invasive hemodynamic reassessment. Clinical TIPS dysfunction (CD) was defined as symptom recurrence, while HD was defined by a portal pressure gradient (PPG)≥12 mmHg. The predictive capabilities of Doppler US for predicting TIPS dysfunction were tested against the hemodynamic gold standard.

Results  86 patients were included. Secondary prophylaxis of variceal bleeding was the main indication for TIPS in 72 patients (83.7%), while 27 (31.4%) had refractory ascites. HD occurred in 37 cases (43%), of which 25 patients (67.5%) had no CD. Patients with HD had a significantly lower portal vein velocity (PVV): 35 (20–45) cm/s vs. 40.5 (35–50) cm/s, p=0.02. Compared to the immediate post-TIPS assessment, the patients without HD had a ΔPVV of 6.08±19.8 cm/s vs. a decrease of − 8.2±20.2 cm/s in HD (p=0.04). Using a cut-off value of 40.5 cm/s, PVV had an AUROC of 0.705 for predicting HD, while the addition of ΔPVV (cut-off 9.5 cm/s) improved the AUROC to 0.78.

Conclusion  Despite adequate symptom control, a considerable percentage of patients have a post-TIPS PPG≥12 mmHg. The dynamic assessment of PVV and its temporal dynamics can reliably predict TIPS dysfunction.
Diagnostic work-up of bile duct strictures: European Society of Gastrointestinal Endoscopy (ESGE) Guideline
Authors: Facciorusso Antonio , Crinò Stefano Francesco , Gkolfakis Paraskevas , Spadaccini Marco , Arvanitakis Marianna , Beyna Torsten , Bronswijk Michiel , Dhar Jahnvi , Ellrichmann Mark , Gincul Rodica , Hritz Istvan , Kylänpää Leena , Martinez-Moreno Belen , Pezzullo Martina , Rimbaş Mihai , Samanta Jayanta , van Wanrooij Roy L.J. , Webster George , Triantafyllou Konstantinos
Published: December 2024

Main recommendations

1 ESGE recommends the combination of endoscopic ultrasound-guided tissue acquisition (EUS-TA) and endoscopic retrograde cholangiopancreatography (ERCP)-based tissue acquisition as the preferred diagnostic approach for tissue acquisition in patients with jaundice and distal extrahepatic biliary stricture in the absence of a pancreatic mass.

2 ESGE suggests that brushing cytology should be completed along with fluoroscopy-guided biopsies, wherever technically feasible, in patients with perihilar biliary strictures.

3 ESGE suggests EUS-TA for perihilar strictures when ERCP-based modalities yield insufficient results, provided that curative resection is not feasible and/or when cross-sectional imaging has shown accessible extraluminal disease.

4 ESGE suggests using standard ERCP diagnostic modalities at index ERCP. In the case of indeterminate biliary strictures, ESGE suggests cholangioscopy-guided biopsies, in addition to standard ERCP diagnostic modalities. Additional intraductal biliary imaging modalities can be selectively used, based on clinical context, local expertise, and resource availability.
Effekte von Genesungsbegleitung in der Psychiatrischen Versorgung:
Ein Systematischer Review of Reviews
Authors: Walde Peggy , Völlm Birgit
Published: December 2024

Ziel Der vorliegende systematische Literaturreview fasst
Überblicksarbeiten zu Effekten von Genesungsbegleitung in formalen
klinischen psychiatrischen Settings zusammen, um so ein umfassendes Bild
über den aktuellen Stand der Evidenz zu erhalten.

Methode Suche in fünf elektronischen Datenbanken nach relevanten
Überblicksarbeiten zu Effekten von Genesungsbegleitung im psychiatrischen
Setting. Die Datenbanksuche wurde durch eine Handsuche ergänzt.

Ergebnisse 16 Reviews wurden gefunden. Diese betrachten vorrangig
klinische und psychosoziale Outcomes. Keine konsistenten Effekte werden im
Zusammenhang mit klinischen Outcomes berichtet. Eine geringe positive
Tendenz zeichnet sich für die psychosozialen Outcomes ab.

Schlussfolgerung Die Autor*innen der Reviews beklagten durchgehend die
geringe Qualität der Ausgangsstudien. Daher können die vorliegenden
Ergebnisse eher als vorläufige Tendenz interpretiert werden. Weitere Studien
sind nötig, um die Wirkung von Genesungsbegleitung differenzierter
betrachten zu können.
Onasemnogene Abeparvovec is Safe in Hemolytic Disease of the Newborn: A Case Report
Authors: Almomen Momen , Edoussouki Maher L. , Aldossary Shaikhah , Atawi Tasneem
Published: December 2024

Spinal muscular atrophy (SMA) is a rare autosomal recessive genetic disease caused by Survival Motor Protein 1 (SMN1) gene mutations. Classically divided into three types, SMA is characterized by hypotonia, weakness, and tongue fasciculation in the first 6 months of life in type 1, inability to walk and limb weakness in type 2, and failure to run with proximal weakness in type 3 SMA. With the advent of newborn screening, treating presymptomatic patients with Onasemnogene abeparvovec (OA) is the treatment of choice in some centers worldwide. The incidence of jaundice is high in this age group, with no recommendation to guide the use of OA in newborns with jaundice. To our knowledge, treating an SMA patient with alloimmune hemolytic disease of the newborn (HDN), a relatively common disease in the newborn period, has never been reported in the past. We report our experience with dosing a presymptomatic child with SMA who had neonatal jaundice and hemolytic anemia due to hemolytic disease of the newborn who tolerated the treatment well. To our knowledge, this is the first case to report the safety of this novel treatment for an SMA patient with alloimmune HDN.
Reductive Ring Opening of Cyclic Amines: Pyrrolidines and Beyond
Authors: Aida Kazuhiro , Ota Eisuke , Yamaguchi Junichiro
Published: December 2024

The reductive ring opening of cyclic amines is powerful strategy for transforming cyclic structures into entirely different molecular frameworks, with significant potential application in synthetic and medicinal chemistry. Previously reported methods have primarily been mainly limited to highly strained substrates such as aziridines and azetidines. In this study, we reported a novel approach for generating carbon-centered radicals upon ring openingfrom less strained cyclic amines, particularly pyrrolidines, using Lewis acid and photoredox catalysis. Notably, while still in its early stages, this method shows potential applicability to larger rings, such as six- and seven-membered systems. Here, we detail the development, scope, and potential of this method, demonstrating efficient and selective reactions of a range of cyclic amines.