bluuebunny/crossref_metadata_2025 huggingface dataset:
Scope of Practice for Occupational Health Nurses: A Concept Analysis Based on Walker and Avant Methods
Authors: Onyeador Colette C. , Umberger Reba A.
Published: November 2023

Purpose. The purpose of this paper is to analyze the concept of scope of practice for occupational health nurses. Background. Occupational health nurses (OHNs) practice in different industries alone or with other nurses, providing care to employees. The demand on occupational health nurses to respond to increasing organizational healthcare needs of employees and other healthcare demands raises the question, do occupational health nurses understand their scope of practice? Occupational health nurses inadvertently practicing outside their scope may jeopardize their nursing licenses, and the safety and quality of care of employees. Method. A literature review was conducted to identify defining attributes, antecedents, and consequences for the concept of scope of practice for OHNs. Walker and Avant’s eight-step framework for concept analysis was applied. Results. The defining attributes of the scope of practice for OHN include but are not limited to standards and guidelines: competency, public safety; practicing certificates; using sound judgement; regulatory restrictions, limitations of practice in occupational health settings, and type of educational qualifications. The antecedents include education, training, competency, regulation, and experience. The consequences include improved quality care when education, training, and competencies are met within the practice guidelines. Possible disciplinary actions against the nurse and employer violation of workplace safety standards may occur. Conclusion. OHNs must understand and practice within their scope of practice even when placed in situations by their employers that could defy the limits of their practice. Defining the scope of practice for OHNs will lay the framework for research studies.
Resúmenes Analíticos de las Tesis del Programa de Magíster en Contabilidad y Auditoría, Primera Parte
Authors: Caiceo Escudero Jaime , Ulcen Cabrera Carlos
Published: November 2023

Se difunden las tesis realizadas en el Programa de Magíster en Contabilidad y Auditoría de la Universidad de Santiago de Chile, a través de resúmenes analíticos para que sirvan de fuente para investigaciones futuras, tanto para alumnos como también para la comunidad científica en general. En esta ocasión se presentan 67 resúmenes analíticos de una parte de las tesis realizadas entre los años 2002 y 2010. Se agrupan en cinco áreas: Auditoría (39), Contabilidad (3), Control de Gestión (18), Costos (3) y Finanzas (4); la cantidad en cada área revela el peso que tiene el control -base de la Auditoría-, dentro del Programa, puesto que si se suman las áreas de Auditoría y Control de Gestión se obtiene un 85% con ese enfoque.
Operationalization of parameters and diagnostics of personal identity
Authors: Makarevskaya Yuliya E. , Ryabikina Zinaida I.
Published: November 2023

Background. In modern conditions of existence, it is difcult to talk about the stability of a person’s identity: it fuctuates, transforms, multiplies, and disappears. Te instability of identity is manifested not only in the problems of self-determination, adaptation, self-realization, but also in the risks of losing the opportunity to be a subject of one’s own life, to consciously identify and responsibly present oneself to the outside world. Te research shows that personal identity provides internal harmony and stability of the subject. However, currently we don’t have a corresponding diagnostic tool with satisfactory psychometric indicators, which makes it difcult to study, monitor, and determine available resources for maintaining the stability of the personality in a changing world. Objective. Te study was aimed at creation and psychometric verifcation of the methodology for diagnostics of personal identity, providing empirical verifcation of its structure, assessment of validity, internal consistency, and retest reliability. Methods. Te study implemented the methods of semi-structured interview, unfnished sentences, survey, expert assessments, calculation of statistical correlation coeffcients and comparison of averages, factor analysis as well as standardization procedures and psychometric checks of validity and reliability of the test. Sample. Te total volume of the research measurements was carried out on a sample of 1,384 people (36.8% men, 63.2% women) aged 13 to 90. Results. Te results of psychometric verifcation of the test (N = 500) showed a satis- © Makarevskaya Y.E., Ryabikina Z.I., 2023 27 factory degree of internal consistency, retest reliability of the scales (factors) “refected Self ”, “unique Self ” and variability of the values on the “personal Self ” scale. Conclusion. Te methodology can be used in the scientifc and practical activities of psychologists specializing in the problems of personality psychology, in the diagnostics of self-identifcation processes of personality in various life situations and in diferent periods of life, while determining the stability of personality in conditions of social change.
Scientifc and everyday ideas in the world view of modern students of early adolescence
Authors: Andreeva Alla D.
Published: November 2023

Background. Te modern information space containing both reliable and quasi-scientifc information has a signifcant impact on the formation of students’ scientifc worldview. Objective. To obtain an empirical support for the theoretical model of the formation of scientifc worldview in the middle-adolescent students which was formulated in the framework of the cultural-historical conception. Methods. A special questionnaire was developed containing 16 pairs of statements. Each pair presented both scientifc and an everyday interpretation of a natural science phenomenon. Te respondents had to choose the answer considered to be correct. When processing the data, the number of answers corresponding to the modern scientifc concepts was taken into account. Sample. Te study involved 200 high school students and 196 junior college students aged 16–18 years, a total of 396 people (232 girls and 164 boys). Results. Te study has revealed that the worldview of middle-adolescent students is predominantly characterized by an average level of scientifc concepts and presents an individual combination of scientifc and everyday knowledge. It has been found out that boys demonstrate a signifcantly higher level of scientifc views than girls. College students’ outlook tends to be more scientifc than that of high school students, but the diferences linked to the type of educational institution do not reach statistica signifcance. Conclusion. Te theoretical model of scientifc worldview formation in the middle adolescence proposed by L.I. Bozhovich in the framework of cultural-historical approach is not confrmed. It is assumed that the key factor in the formation of an individual’s scientifc worldview is not the scope of one’s knowledge but its personal meaning. Te data obtained expand understanding of formation of the students’ worldview and provide new insights into the content and structure of modern individual’s outlook.
Features of imagination in 5–6-year-old children
Authors: Almazova Olga V. , Bukhalenkova Daria А. , Chichinina Elena А.
Published: November 2023

Background. Te relevance of the study is due to understanding of important role of imagination in the cognitive and emotional development of children as well as the contradictory results of modern research on imagination development in older preschool age. Objective. Te study had its purpose to assess the level of productive imagination of the present-day preschoolers educated in the senior groups of kindergarten and to identify types of imagination being based on statistical data processing. Methods. Te study implemented the technique “Complete the drawing” (a modifed Torrens’ Test) and the typology of productive imagination by O.M. Dyachenko (2007). Drawings of preschoolers were analyzed in terms of elaboration, fexibility, and originality of images. Processing the obtained data included calculation of the mean and median values, standard deviations; the cluster analysis method; the non-parametric Kruskal-Wallis’s criterion and Kolmogorov-Smirnov’s, Mann-Whitney’s criteria were used. Sample. Te study involved 768 preschoolers of older groups of kindergartens in four regions of Russia (Moscow, the Republics of Sakha and Tatarstan, Perm Territory) aged 58 to 72 months (of which 47.9% were boys). Results. Modern methods of statistical data processing have made it possible to identify and compare signifcantly diferent types of productive imagination in preschoolers. According to the results of the assessment of imagination development of the of older preschool children in diferent regions of Russia, a similar distribution was obtained for 6 types of productive imagination. Te study revealed the low level of imagination development in about half of older preschoolers: children either do not accept the task at all (type 0), or draw individual objects that are not detailed (type 1). Productive imagination at the age of 5–6 years develops heterochronously: children with diferent types of imagination have relatively high scores for various parameters (types 2, 3, 4). Less than 5% of older preschoolers are characterized by a high level of imagination development when children use “inclusions” (type 5). Conclusion. Te results of the study expand the understanding of productive imagination in today’s preschool children and contribute to studying its development in the changed conditions of educational environment. Te typology of productive imagination built on the basis of quantitative methods can be useful for both researchers and practicing psychologists, preschool educators.
Towards an ‘Eco-Theo-Logy’
Authors: Kureethadam Joshtrom Isaac
Published: November 2023

The paper seeks to draw the contours of an “Eco-Theo-Logy” in the context of the unprecedented crisis of our Common Home and with special reference to Laudato Si’, Pope Francis’ landmark encyclical on creation care. An “eco” theology would begin with the sense of awe and gratitude for Earth, our unique common planetary home blessed with the gift of life, and listen attentively to the growing “cry of the Earth and of the poor” (Laudato Si’, 49). Secondly, it seeks to articulate anew the theological understanding of an ‘in-carnate’ God, a God who enters human and cosmic vicissitudes and manifests in the pangs of creation. It also strives to a religious vision of the natural world as the “Gospel of creation”. Thirdly, it’s time to re-imagine the logos component of an eco-theo-logy, embracing an integral and relational approach, raising a prophetic theological voice in the face of profound inequalities and injustices that exist in our one common household, and adopting a decisively practice/action orientation.
The Role of ʿAjamī in Hausa Literary Production
Authors: Yanco Jennifer J , Kurfi Mustapha Hashim
Published: November 2023

Islamic education and literacy were present in Hausaland long before the jihad of Usman ɗan Fodio, which culminated in the establishment of the Sokoto Caliphate in 1804. While ʿAjamī made its way into Hausaland with the spread of Islam, its use today is not limited to sacred or religious texts. In fact, it serves as a medium for the diffusion of information through newspapers, personal correspondence, political and advertising signage, poetry, and even currency notes. At the same time, the Islamic values that inform Hausa culture are an integral aspect of these materials. Over time, Hausa scholars adapted the Warsh-based Arabic script to the particularities of the Hausa language, resulting in Hausa ʿAjamī’s enriched inventory of characters and diacritics. The ʿAjamī tradition remains strong and widespread, as shown in our collection of 20 manuscripts, most from the 20th century, that highlight a range of personal qualities valued by the Hausa people.
ʿAjamī Script in Senegambian Mandinka Communities
Authors: Cisse Ousmane
Published: November 2023

The article discusses the rich oral and written traditions of the Mandinka communities in West Africa. Their oral traditions, which are embodied by the jali (griot) caste, have served for centuries to transmit multiple forms of knowledge between generations. Besides their oral traditions, multiple forms of literacy coexist with illiteracy in the Mandinka communities in Senegambia. The first form of literacy in Mandinka communities is ʿAjamī. Currently, ʿAjamī remains the primary means of written communication for many Mandinka speakers in Senegambia. They keep their records of various events and transmit various forms of knowledge in this medium. Using selected Mandinka ʿAjamī texts, this paper focuses on the innovations that Mandinka scholars have made to the classical Arabic script in order to develop their own ʿAjamī writing system. I discuss the people who use the system, the types of texts that are produced, and the broader social and cultural significance of ʿAjamī in Senegambian Mandinka communities.
Aleocharine rove beetles of New Hampshire, USA: new taxa and new records (Coleoptera, Staphylinidae, Aleocharinae)
Authors: KLIMASZEWSKI JAN , CHANDLER DONALD S. , DAVIES ANTHONY , BOURDON CAROLINE
Published: November 2023

Based on the specimens housed primarily in the University of New Hampshire Insect Collection (UNH) and the Canadian National Collection (CNC), we present here a comprehensive faunal review of aleocharine beetles of the state and provide new distribution and natural history data. We report 252 species from New Hampshire belonging to some 74 genera in 15 tribes; 159 of these constitute new New Hampshire state records (NSR), of which 37 (excluding new species and including 1 New York record) constitute new country distribution records (NCR) for the USA. In addition, we provide 36 new state records for ME, with 5 of these species not yet known from NH, seven new state records for MA, two new state records for PA and VT, and one each for CT, DE, MI, NC, NY (also a NCR), OH, and OK. One new genus, Belladonna Klimaszewski and Chandler is erected, and nine species are described as new to science (alphabetical order): Agaricomorpha hampshirensis Klimaszewski and Chandler, sp. n., Atheta ellisi Klimaszewski and Chandler sp. n, Atheta monroe Klimaszewski and Chandler, sp. n., Atheta struyvei Klimaszewski and Chandler sp. n, Belladonna barryi Klimaszewski and Chandler, sp. n., Belladonna fortieri Klimaszewski and Chandler, sp. n., Colusa smetanai Klimaszewski and Chandler, sp. n., Philhygra pinkhami Klimaszewski and Chandler sp. n., and P. pseudomagniceps Klimaszewski and Chandler, sp. n. Undescribed females of Aleochara daviesi Klimaszewski and Brunke, and Silusa langori Klimaszewski, are described and illustrated. Illustrations of Atheta (Tetropla) tubericauda Bernhauer are provided for the first time, based on a male from New Hampshire. A new combination is proposed for Atheta (Dimetrota) mcalpinei Klimaszewski and Webster.
5. Listening
Authors: Weizsäcker Georg
Published: November 2023

Chapter 5 discusses the analogous belief for the listener, the “first-order listening belief”. It comes in two variants, depending on whether the listener learns about the state of the world or about the talker’s subsequent actions – e.g., the actions that may follow after a promise is made. Like for the talker, the listener’s belief is conditional on information about the other person’s type and about the context, and the chapter discusses the importance of whether or not the listener realizes the relevance of such information. Notably, the empirical evidence reported in this chapter points to an insufficient conditioning of listening beliefs.
10. Conclusion
Authors: Weizsäcker Georg
Published: November 2023

Chapter 10 concludes the book, briefly summarizing the ideas explored within each chapter. Alongside these summaries, this chapter compares the ideas explored and addresses the concepts behind them. Here, the writer also elaborates on how these ideas can be applied, along with establishing that this book is not an exhaustive guide to every instance of discussion – as such, it cannot predict every outcome perfectly, but it is an example of some of the many forms conversations can take.
Plasma indole-3-aldehyde as a novel biomarker of acute kidney injury after cardiac surgery: a reanalysis using prospective metabolomic data
Authors: Hu Linhui , Bai Yunpeng , Lai Changchun , Mo Leitong , Li Ying , Jiang Xinyi , Xu Wang , He Yuemei , Zhou Xinjuan , Chen Chunbo
Published: November 2023

Background

Acute kidney injury (AKI) is a frequent complication of cardiac surgery that poses significant risks for both the development of chronic kidney diseases and mortality. Our previous study illustrated that heightened expression levels of faecal and plasma indole metabolites before the operation were associated with ischemic AKI. In this study, we aimed to validate the supposition that plasma indole-3-aldehyde (I3A) could serve as a predictive biomarker for AKI in patients undergoing cardiac surgery.

Methods

This statistical reanalysis utilized AKI metabolomic data from patients scheduled for cardiac surgery between April 2022 and July 2022 in two tertiary hospitals. Faecal and blood samples were prospectively collected before surgery within 24 h, and variables related to the preoperative, intraoperative, and postoperative periods were recorded. AKI diagnosis was based on the Kidney Disease Improving Global Outcomes criteria.

Results

In this study, 55 patients who underwent cardiac surgery were analyzed, and 27 of them (49.1%) developed postoperative AKI. Before surgery, these patients had significantly higher levels of faecal indole metabolites, including skatole, trans-3-indoleacrylic acid, and 5-methoxyindoleacetic acid. The plasma I3A, clinical model that considered perioperative and intraoperative variables, and their combination had area under the receiver operating characteristic curve (ROC) values of 0.79 (95% CI 0.67–0.91), 0.78 (95% CI 0.66–0.90), and 0.84 (95% CI 0.74–0.94) for predicting AKI, respectively. Furthermore, by utilizing net reclassification improvement and integrated discrimination improvement, plasma I3A showed significant improvements in risk reclassification compared to the clinical model alone.

Conclusions

The dysregulation of gut microbiota metabolism in patients scheduled for cardiac surgery can result in an increase in indoles from tryptophan metabolism, which may be associated with postoperative acute kidney injury (AKI). This suggests that indoles may serve as a predictive biomarker for AKI in patients undergoing cardiac surgery.
Effectiveness of an educational intervention to promote psychosocial well-being of school-going adolescents in Sri Lanka
Authors: Vithana Chiranthika , Lokubalasooriya Ayesha , Pragasan Ganeshamoorthy , Mahagamage Kanchana Lanka , Nanayakkara Kumudumalee , Herath Himali Prasangika , Karunarathna Priyani , Perera Nadeeka , de Silva Chithramalee , Jayawardene Dushyanthi , Wickramasinghe Nuwan Darshana
Published: November 2023

Background

One-fifth of the Sri Lankan population consists of adolescents, with 71% of them schooling. An extreme need exists in the country for the introduction of evidence-based interventions for the psychosocial well-being of adolescents. The present study assessed the effectiveness of an educational intervention to promote the psychosocial well-being of school-going adolescents in grade nine in Western Province, Sri Lanka.

Materials and methods

A quasi-experimental study was conducted among grade nine students in Western Province in 2019. Panadura Medical Officer of Health (MOH) area was selected as the interventional area (IA), and Kelaniya MOH area was identified as the control area (CA). Teachers at schools in the IA received training on psychosocial health promotion of adolescents. They delivered the activity-based educational intervention package to the grade nine students as 20-min classroom sessions for three months. Pre- and post-intervention assessments of attitudes and practices related to the psychosocial well-being of adolescents were conducted using an interviewer-administered questionnaire. Categorical data were compared using Chi-Square or Fisher’s exact test. Mann–Whitney U test was applied to determine the difference between the medians of the pre-and post-intervention scores on attitude and practices for psychosocial well-being.

Results

A total of 1040 grade nine students were enrolled. There was a statistically significant increase in median score on attitudes [81.8 (IQR:75.5–85.5) to 82.3(IQR:78.6–87.2] and practices [81.7(IQR: 76.1–85.7) to 83.1(IQR: 79.1–86.9)] in the IA while there was no significant difference in the CA. The proportion of bullied adolescents in the past 30 days reduced significantly from 14.8% (n = 38) to 7.9% (n = 20) in IA(p = .03), whereas there was a slight reduction from 17.1% (n = 44) to 11.3% (n = 26) in CA (p = .17).

Conclusions

The present psychosocial intervention is effective in improving the psychosocial well-being of school adolescents, though long-term effectiveness was not assessed. It is recommended to utilise study findings in deciding to introduce the present intervention to basic and in-service teacher training packages and school curricula with necessary modifications.
Anterior fusion surgery with overcorrection in the treatment of adolescent idiopathic scoliosis with Lenke 1 AR curve type: how to achieve overcorrection and its effect on postoperative spinal alignment
Authors: Tanaka Nobuki , Inami Satoshi , Moridaira Hiroshi , Sorimachi Tsuyoshi , Ueda Haruki , Aoki Hiromichi , Takada Satoshi , Nohara Yutaka , Haro Hirotaka , Taneichi Hiroshi
Published: November 2023

Background

The efficacy of anterior fusion with overcorrection in the instrumented vertebra for Lenke 1 AR type curves has been reported, but how to achieve overcorrection and how overcorrection affects spinal alignment are unclear. The purpose of this study was to identify the factors that cause overcorrection, and to investigate how overcorrection affects postoperative spinal alignment in the surgical treatment of Lenke 1 AR type curves.

Methods

Patients who had anterior surgery for a Lenke type 1 or 2 and lumbar modifier AR (L4 vertebral tilt to the right) type scoliosis and minimum 2-year follow-up were included. The radiographic data were measured at preoperative, postoperative 1 month, and final follow-up. The UIV-LIV Cobb angle was determined as the Cobb angle between the upper instrumented vertebra (UIV) and the lower instrumented vertebra (LIV), and a negative number for this angle was considered overcorrection. The screw angle was determined to be the sum of the angle formed by the screw axis and the lower and upper endplates in the LIV and UIV, respectively. The change (Δ) in the parameters from postoperative to final follow-up was calculated. The relationships between the UIV-LIV Cobb angle and other radiographic parameters were evaluated by linear regression analyses.

Results

Fourteen patients met the inclusion criteria. Their median age was 15.5 years, and the median follow-up period was 53.6 months. The median UIV-LIV Cobb angle was –1.4° at postoperative 1 month. The median screw angle was 4.7°, and overcorrection was achieved in 11 (79%) cases at postoperative 1 month. The screw angle (r2 = 0.42, p = 0.012) and Δ FDUV-CSVL (the deviation of the first distal uninstrumented vertebra from the central sacral vertical line, r2 = 0.53, p = 0.003) were significantly correlated with the UIV-LIV Cobb angle.

Conclusions

Screw placement in the UIV and LIV not parallel to the endplate, but angled, was an effective method to facilitate overcorrection in the instrumented vertebrae. The results of the present study suggest that overcorrection could bring spontaneous improvement of coronal balance below the instrumented segment during the postoperative period.
Uptake of retroviral pre-exposure prophylaxis and its associated factors among female sex workers, Northwest Ethiopia
Authors: Shibesh Belayneh Fentahun , Admas Aragaw Bitew , Lake Amarech Wondie , Getu Samuel Befekadu , Worede Daniel Tarekegn
Published: November 2023

Background

Pre-exposure prophylaxis is the use of antiretroviral medications by HIV-negative individuals to prevent infection before exposure. Ethiopia has made progress in reducing new HIV infections, but the burden remains high with ongoing challenges in prevention uptake. This study examined the utilization and factors associated with pre-exposure prophylaxis among female sex workers.

Methods

A community-based cross-sectional study design was conducted in Bahir Dar city administration among female sexual workers in 2022. The results were collected using a pre-tested and structured questionnaire. Epi data for data entry and social package for social science for analysis were used.

Result

Overall, 15.9% (CI: 12.0-21.1) of female sexual workers received pre-exposure prophylaxis. Parents’ living condition (only father alive [AOR = 0.23, 95% CI, 0.02–0.64], only mother alive [AOR = 0.31, 95% CI, 0.02–0.74]), marital status being single (AOR = 0.27, 95% CI, 0.06–0.94), having history of STI (AOR = 2.82, 95% CI, 1.60–4.77) were associated with pre-exposure prophylaxis uptake.

Conclusion

This study showed low pre-exposure prophylaxis uptake. The study identified a history of sexually transmitted infections, marital status, and parent living conditions as significant factors. To increase pre-exposure prophylaxis uptake and reduce HIV incidence, an awareness campaign, tailored support, targeted interventions, and addressing concerns of high-risk groups are needed.
Influence of the 2000-m ergometer test on indirect markers of intestinal injury in competitive elite rowers in different training phases
Authors: Dziewiecka Hanna , Kasperska Anna , Ostapiuk–Karolczuk Joanna , Cichoń-Woźniak Justyna , Basta Piotr , Skarpańska-Stejnborn Anna
Published: November 2023

Background

We examined the effect of the 2000-m ergometer test on gut injury in competitive elite rowers in two different training phases. Given that inflammatory markers during the competitive phase are higher, we hypothesise that markers of intestinal injury are also more elevated during that phase.

Methods

We performed this study during the preparatory phase (Test I) and competitive phase (Test II) of annual training. We included 10 competitive elite rowers, members of the Polish Rowing Team, in the study after applying the inclusion/exclusion criteria. The participants performed a 2000-m ergometer test during both phases (Tests I and II). We collected blood samples before the test, immediately after the test and after 1 h of recovery. We measured the levels of interleukin 6 (IL-6), intestinal fatty acid binding protein (I-FABP), lipopolysaccharide (LPS), lipopolysaccharide-binding protein (LBP), and zonulin.

Results

There were no significant changes over time in Test I and Test II in the gut integrity markers. There were significantly lower I-FABP and IL-6 levels after the test for Test II compared with Test I. The pre-test LPS level was significantly lower for Test II compared with Test I. The pre-test LBP and zonulin levels were numerically lower in Test II, but the differences were not significant.

Conclusions

The 2000-m ergometer test showed no influence on gut integrity markers. However, there were differences in the response to exercise between Tests I and II. The lower level of gut injury markers after extreme exercise tests carried out during the preparation period may be the result of adaptive mechanisms and could indicate that rationally conducted training significantly decreases intestinal injury.
Surgical strategies and outcomes for myocardial bridges coexisting with other cardiac conditions
Authors: Zhang Mingkui , Xu Xiruo , Wu Qingyu , Li Hongyin , Xu Zhonghua , Xue Hui , Jin Yongqiang , Fan Lixin , Li Lina
Published: November 2023

Background

Myocardial bridges are congenital coronary artery anomalies. There are still many controversies surrounding surgical treatment strategies for myocardial bridges combined with other heart disorders. The purpose of this study was to evaluate the surgical treatment strategies and outcomes in patients with these conditions.

Methods

Between March 2004 and October 2021, our institution witnessed 77 patients diagnosed with myocardial bridging who underwent surgical intervention. According to the myocardial bridge and combined heart disorder, four groups were identified: 1. isolated LAD supra-arterial myotomy group, 2. LAD CABG and(or not) myotomy  group, 3. LAD supra-arterial myotomy and grafting of other branches group, and 4. LAD supra-arterial myotomy and other cardiac surgery group. The perioperative outcomes, symptoms, life quality, mortality, and major adverse cardiac events (MACEs) were analyzed.

Results

There were no deaths during hospitalization and no rethoractomy for postoperative bleeding or major adverse cardiac events (MACEs). The follow-up period ranged from 2 months to 199.2 months (55.61 ± 10.21) months, the 10-year cumulative survival rates for the four groups of patients were 95.0%, 100%, 100% and 74.1%, and the 10-year freedom rates from the MACEs were 83.9%, 92.0%, 87.5% and 76.2%, respectively.

Conclusions

Supra-arterial myotomy is preferred in patients with isolated myocardial bridge, and acceptable results can be achieved by choosing supra-arterial myotomy in combination with CABG or other cardiac surgery simultaneously for patients with myocardial bridges and other heart disorders.
Multisystem Inflammatory Syndrome (MIS) following SARS-CoV-2 vaccinations; a systematic review
Authors: Elsaid Mohamed , Nune Arvind , Hesham Deyaa , Fouad Fatma Mohamed , Hassan Hamsa , Hamouda Heba , Sherif Huda , Abdelwahab Maya Magdy , Hegazi Nourelhoda , El-Rahman Yasmena Abd
Published: November 2023

Background

Although SARS-CoV-2 vaccines are generally safe, there are growing concerns about their link to a potentially life-threatening multi-system inflammatory syndrome following vaccination (MIS-V). We conducted this systematic review to elucidate the prevalence of MIS, severity, treatment, and outcomes following SARS-CoV-2 vaccination.

Methods

We searched PubMed, Scopus, ScienceDirect, Google Scholar, Virtual Health Library (VHL), Cochrane Library, and Web of Science databases for articles and case reports about MIS-V. We performed a qualitative analysis of individual cases from the included studies.

Results

Of the 1366 studies identified by database search, we retrieved twenty-six case reports and two cohort studies. We analyzed the data of 37 individual cases extracted from 27 articles. The average age of the cases included in this review was 18 (1–67) years, with the most being male (M: F 3.1:1). Of the 37 included cases, the cardiovascular system was the most affected system by MIS (36, 97.3%), followed by the gastrointestinal tract (32, 86.5%).

Conclusion

MIS after SARS-CoV-2 vaccinations can be fatal, but the incidence is low. Prompt recognition of MIS and ruling out the mimickers are critical in the patient’s early recovery.
Thyroid and Adrenal Dysfunction in Hemoglobinopathies Before and After Allogeneic Hematopoietic Cell Transplant
Authors: Mandava Mamatha , Lew Jeffrey , Tisdale John F , Limerick Emily , Fitzhugh Courtney D , Hsieh Matthew M
Published: November 2023

Purpose

To determine the rate and clinical characteristics associated with abnormal thyroid and adrenal function in recipients of nonmyeloablative hematopoietic cell transplantation (HCT) for sickle cell disease (SCD) and beta-thalassemia.

Methods

We retrospectively reviewed patients who enrolled in 4 nonmyeloablative HCT regimens with alemtuzumab and total body irradiation (TBI). Baseline and annual post-HCT data were compared, which included age, sex, sickle phenotype, thyroid panel (total T3, free T4, thyroid stimulating hormone, antithyroid antibodies), cortisol level, ACTH stimulation testing, ferritin, medications, and other relevant medical history.

Results

Among 43 patients in haploidentical transplant and 84 patients in the matched related donor protocols with mostly SCD, the rate of any thyroid disorder pre-HCT was 3.1% (all subclinical hypothyroidism) and post-HCT was 29% (10 hypothyroidism, 4 Grave's disease, and 22 subclinical hypothyroidism). Ninety-two (72%) patients had ferritin >1000 ng/dL, of which 33 patients (35.8%) had thyroid dysfunction. Iron overload was noted in 6 of 10 patients with hypothyroidism and 12 of 22 patients with subclinical hypothyroidism.

Sixty-one percent were on narcotics for pain control. With respect to adrenal insufficiency (AI) pre-HCT, 2 patients were maintained on corticosteroids for underlying rheumatologic disorder and 8 had AI diagnosed during pre-HCT ACTH stimulation testing (total 10, 7.9%). Post-HCT, an additional 4 (3%) developed AI from corticosteroid use for acute graft vs host disease, Evans syndrome, or hemolytic anemia.

Conclusion

Although iron overload was common in SCD, thyroid dysfunction pre-HCT related to excess iron was less common. Exposure to alemtuzumab or TBI increased the rates of thyroid dysfunction post-HCT. In contrast, AI was more common pre-HCT, but no risk factor was identified. AI post-HCT was infrequent and associated with corticosteroid use for HCT-related complications.
Promising areas of research of professional activity of employees of metallurgical industries
Authors: Gavryushkin Roman
Published: November 2023

The article discusses promising areas of research of professional activity of workers of metallurgical industries. The practice of taking into account occupational risks and occupational morbidity of employees of metallurgical industry enterprises shows that inefficient performance of labor functions in the course of professional activity may be associated with a distorted idea of the requirements that are imposed on the subject of labor and its professionally important qualities, and this, in turn, requires a certain professional readiness and adaptation to working conditions based on selection of coping strategies appropriate to the professional situation. One of the contradictions may be the current requirements for the professionally important qualities of employees of metallurgical industries, for their performance of certain labor functions within a particular position in accordance with professional standards and the inconsistency of the existing professional and personal characteristics of employees with existing qualification requirements. The assessment of the degree of digital support of metallurgical devices and production in general makes it possible to optimize not only the policy of economic development in general, but also the professional activity of an employee of metallurgical industries, in particular – on machines with software and in the management of complex production complex systems. Considering professional training as a dynamic process of forming an employee of metallurgical industries, such trends and priority areas of educational activity as the use of a collective form of educational interaction, the implementation of a differentiated approach to students, the use of electronic and mixed learning, the use of virtual and augmented reality technologies in educational practice, individualization of training and mentoring are highlighted. The implementation of the institute of mentoring in the metallurgical sphere is significant for increasing the success of the enterprise and, importantly, for the development of a person, an employee as a person and as a subject of activity, the disclosure of his professional and personal qualities in work, as a professional at various stages of professionalization. The identified promising areas of research of the professional activity of workers of metallurgical industries can lay the foundation for the creation and implementation of a systematic approach, a model of psychological support of professional activity aimed at the development of professional and personal constructive mechanisms of professional adaptation within the framework of professional activity in the metallurgical sphere.
Volunteers’ psychological condition during the war in Ukraine – a survey
Authors: Rodek Patryk , Kucia Karolina , Pastuszka Artur , Mędrala Wojciech , Kucia Krzysztof
Published: November 2023

Cel pracy

Celem pracy była ocena wpływu wolontariatu na kondycję psychiczną wolontariuszy w trakcie wojny w Ukrainie.

Metoda

Wykorzystując platformę społecznościową "Facebook" woluntariusze zostali poproszeni o wypełnienie autorskiego kwestionariusza, dotyczącego ich kondycji psychicznej. Link do ankiety pozostawał otwarty od kwietnia do maja 2022 roku. W sumie uzyskano 867 odpowiedzi, z czego do ostatecznej analizy włączono odpowiedzi 703 respondentów. Uczestnicy badania zostali podzieleni na trzy grupy w zależności od tego w jaki sposób wolontariat wpłynął na ich zdrowie psychiczne. Następnie wyodrębniono dwie grupy: woluntariuszy działających na terenie Ukrainy oraz tych przyjmujących uchodźców pod swój dach. W każdej z grup oceniono wpływ wolontariatu na kondycję psychiczną wolontariuszy.

Wyniki

U 45.10% uczestników badania wolontariat miał pozytywny wpływ na kondycję psychiczną, 35.56% respondentów nie stwierdziło żadnego wpływu, a u 19.35% wolontariuszy doszło do pogorszenia kondycji psychicznej. Somatyczne objawy lęku występowały w 11.10% przypadków, a osiągały znaczne nasilenie w 8.25%. 14.10% uczestników częściej sięgało po substancje psychoaktywne. Wśród wolontariuszy przyjmujących uchodźców do swoich domów 52.23% odczuwało nasilone wewnętrzne napięcie i irytację. 18% wolontariuszy działających na terytorium Ukrainy zgłaszało potrzebę pomocy psychiatrycznej lub psychologicznej.

Wnioski

Wpływ wolontariatu na jednostkowe zdrowie psychiczne wolontariuszy waha się od pozytywnego do negatywnego. Wyjściowy nastrój ma znaczący wpływ na kondycję psychiczną po zakończeniu wolontariatu. Zjawisko traumy pośredniej jest wciąż niewystarczająco poznane i wymaga dalszych badań.
Peculiarities of the formation of exocrine pancreatic insufficiency in patients with primary osteoarthritis under conditions of comorbidity
Authors: Halabitska Iryna
Published: November 2023

Summary.  The comorbidity of primary OA and diseases of the gastrointestinal tract, which EPI accompanies, is an extremely relevant, complex, and unstudied problem of modern medicine, as it has a number of unsolved problems both in the treatment and rehabilitation of such patients. Common pathogenetic mechanisms of the progression of such comorbidity often have a mutually aggravating effect, which requires further study.

The aim of the study is to analyze the changes in indicators of exocrine pancreatic insufficiency (EPI) in patients with primary OA under the conditions of comorbidity with diseases of the gastrointestinal tract (GI).

Research material and methods. 304 patients with primary OA in comorbidity with diseases of the gastrointestinal tract accompanied by non-exacerbation EPI were examined. The comparison group consisted of 30 practically healthy individuals who did not have clinical, anamnestic, and instrumental signs of diseases of the gastrointestinal tract and joints.

Results and discussion. It was established that in patients with primary OA in comorbidity with diseases that are accompanied by EPI, the levels of EPI indicators were statistically significantly different depending on the etiology of EPI.

Conclusion. Post hoc analysis established the ranking of the pathology of the gastrointestinal tract, accompanied by EPI, according to the indicators of EPI in primary OA, which was located as follows, starting from the highest: CP ˃ T2DM ˃ chronic non-calculous cholecystitis and functional diseases of the gallbladder and biliary system ˃ chronic gastroduodenitis (p ˂0.05).
A Crown of Appreciative Sonnets
Authors: Mann Ada Jo
Published: November 2023

After retirement, Ada Jo Mann explored poetry through classes at a local bookstore. The sonnet form intrigued her, the crown of sonnets, a ring of fifteen related sonnets that begin and end with the same line. She decided to explore this complicated structure through the lens of a topic close to her heart, Appreciative Inquiry.
Futureproofing the Leadership Pipeline: An Appreciative Inquiry Exploring Reverse Mentoring to Prepare Millennials for Leadership in Pharmaceuticals
Authors: Walton Renata A. , Conrad Kelley A.
Published: November 2023

To futureproof the leadership pipeline at a top worldwide pharmaceutical company, an appreciative inquiry among 75 employees improved the existing reverse mentoring program. Promotion of the study introduced approximately 300 employees to Appreciative Inquiry and the program, and resulted in a 25% increase in program participants. The study contributed to and expanded our understanding of Millennials’ proclivities, reverse mentoring best practices, and offered future practitioners examples for applying AI.
How Business Can Prosper by Building a Better World: A Strengths-Based Approach to Co-Creating Mutual Value
Authors: Mohr Bernard J. , Donnan Susan , Reaves Chris , Samuels Neil , Walter Fritz
Published: November 2023

Businesses could, in partnership with their stakeholders, do even better than they are by identifying and capturing new value-creation opportunities that directly address the 17 UN development goals. Co-creating Mutual Value is an approach to using the positive core of a business, its ecosystem, and engagement of all voices.
RADIOLOGICAL AND CLINICAL OUTCOMES IN ADOLESCENT IDIOPATHIC SCOLIOSIS CORRECTIVE FUSION SURGERY
Authors: Blankson Benjamin , Dunn Robert , Noconjo Lubabalo
Published: November 2023

Adolescent idiopathic scoliosis (AIS) is a complex three-dimensional deformity of the spine characterized by a Cobb angle of at least 10 degrees. The goal of surgery is to not only prevent progression but restore sagittal and coronal balance, protecting cardiopulmonary function and improving cosmesis.

We reviewed the impact of deformity correction surgery in terms of radiology and patient reported outcome(PROMs).

The senior authors prospectively maintained database from 2003 –2022 was retrospectively analysed in terms of pre- and post-operative patient reported outcome measures (SRS 22) as well as radiological parameters.

44 patients with AIS were identified with pre and post op PROMS. The average age at surgery was 15yrs with 84% female. 38% had a Lenke 1 curve and 3 patients had Lenke 6 curves. 73% had posterior surgery.

There was a total improvement in SRS 22 scores by 7.8%. Patients reported significant satisfaction with treatment 4.8/5 and improvement in self-image with a change of 0.4 (p<0.001). However, no difference in function, pain and mental health were recorded.

Overall, proximal thoracic (PT) curves improved from 24 degrees to 11 degrees (p<0.001), Main thoracic (MT) curve 55 degrees to 19 degrees and Thoracolumbar/Lumbar curves (TL/L) 45 degreesto 11 degrees. Pre-operative flexibility and post-operative correction were 0.40 and 0.41 respectively for PT curve. MT was 0.32 and 0.67. That for TL/L was 0.57 and 0.71 respectively.

Surgery yields significant main curve correction correlating with high patient reported satisfaction rate. Although total SRS 22 score yielded 7.8% improvement, sub-analysis of self-image showed the most significant improvement.
MORTALITY IN PATIENTS ADMITTED TO ACUTE SPINAL CORD UNIT IN CAPE TOWN, SOUTH AFRICA
Authors: Kruger Nicholas , Arnolds Delroy , Dunn Rob
Published: November 2023

To analyse the causes and factors associated with mortality in patients admitted to ASCI unit in a low- or middle-income country. The study was performed at a Tertiary Hospital at Groote Schuur Hospital, Cape Town South Africa

Data between 1996 –2022 were retrospectively collected from hospital records of patients admitted to the ASCI Unit. There was approximately 3223 admissions for the study period. 682 patients were confirmed dead 87% were male and 64% were unemployed. The mean age was 46 years (ranging from 14 – 87 years).

A 1/3 of injuries were caused by a MVA, a ¼ by a fall (low energy and from a height), and 1/5 by a gunshot wound. Average length of stay was 47 days (SD = 52 days), ranging from as short as 1 day to 512 days for one patient. Majority (65%) were admitted for more than a week but less than 2 months 32% were ventilated, and 17% with a CPAP facemask. 10% of patients had a pre-existing ulcer prior to admission. 65% of patients had surgery via the posterior approach, 33% via the anterior approach. On average patients died within 5 years of being admitted to hospital, ranging from dying in the same year as the injury to 20 years later. 73% of the deaths were classified as natural deaths and 20% as unnatural.

There is a high mortality in patients with acute spinal cord injury, causes are multifactorial, and in depth critical analyses is required to improve clinical outcomes and rationalise resource allocation.
CLINICAL OUTCOMES FOLLOWING GLENOHUMERAL DISLOCATION WITH GREATER TUBEROSITY FRACTURE
Authors: Hackney Rosemary , Toland Gemma , Crosbie Gearoid , Mackenzi Samuel , Clement Nick , Keating John
Published: November 2023

A fracture of the tuberosity is associated with 16% of anterior glenohumeral dislocations. Manipulation of these injuries in the emergency department is safe with less than 1% risk of fracture propagation. However, there is a risk of associated neurological injury, recurrent instability and displacement of the greater tuberosity fragment. The risks and outcomes of these complications have not previously been reported. The purpose of this study was to establish the incidence and outcome of complications associated with this pattern of injury.

We reviewed 339 consecutive glenohumeral dislocations with associated greater tuberosity fractures from a prospective trauma database. Documentation and radiographs were studied and the incidence of neurovascular compromise, greater tuberosity fragment migration and intervention and recurrent instability recorded.

The mean age was 61 years (range, 18–96) with a female preponderance (140:199 male:female). At presentation 24% (n=78) patients had a nerve injury, with axillary nerve being most common (n=43, 55%). Of those patients with nerve injuries 15 (19%) did not resolve. Greater tuberosity displacement >5mm was observed in 36% (n=123) of patients with 40 undergoing acute surgery, the remainder did not due to comorbidities or patient choice. Persistent displacement after reduction accounted for 60 cases, later displacement within 6 weeks occurred in 63 patients. Recurrent instability occurred in 4 (1%) patients. Patient reported outcomes were poor with average EQ5D being 0.73, QDASH score of 16 and Oxford Shoulder Score of 41.

Anterior glenohumeral dislocation with associated greater tuberosity fracture is common with poor long term patient reported outcomes. Our results demonstrate there is a high rate of neurological deficits at presentation with the majority resolving spontaneously. Recurrent instability is rare. Late tuberosity fragment displacement occurs in 18% of patients and regular follow-up for 6 weeks is recommended to detect this.