bluuebunny/crossref_metadata_2025 huggingface dataset:
Analysis of sequence polymorphism of OsHKT1;5 gene in rice (Oryza sativa L.)
Authors: Huy Duong Nguyen , Xuan An Tran , Phuc Do Thi
Published: August 2022

In salt stress conditions, the excessive accumulation of Na+ ion in the cytoplasm could cause ion toxicity, metabolic imbalances, and reduction in growth of plant. The ability of maintaining a low Na+ concentrations or low Na+/K+ ratio in cytosol plays the important roles of plant adapt to salinity stress. In rice, the HKT transporter family has been proven to be critical for salt tolerance and the maintenance of Na+, K+ homeostasis under salinity conditions. In this study, we conducted the sequence polymorphisms analysis in the OsHKT1;5 coding region in order to detect the potential allelic variants in some local rice cultivars in Viet Nam. The exon 1 region and exon 2-3 region of OsHKT1;5 gene were amplified by PCR in two separate reactions. After direct sequencing of PCR products, the full length coding region of OsHKT1;5 gene was obtained and compared to reference Nipponbare OsHKT1;5 coding sequence.  Accordingly, twelve nucleotide substitutions in coding sequence of OsHKT1;5 were identified, including six non-synonymous substitutions (G382A, C418G, G551A, C994G, C1183G, A1630C) and the other six synonymous substitutions (G225A, C1038G, G1152A, G1261A, G1304C, C1608T).  Further analysis revealed that six non-synonymous substitutions (G382A, C418G, G551A, C994G, C1183G, A1630C) caused the changes in amino acids (D128N, P140A, R184H, H332D, V395L, and S544R). The single nucleotide polymorphism A1630C leading substitution of S544R was newly found in the Chiem Rong cultivar. In silico analysis of protein structure and post-translational modifications indicated that amino acid substitutions had no influence on protein structure but led to changes in post-translational modifications such as phosphorylation and SUMOylation.
Genetic distance and phylogenetic relationships of some Echinostoma species (E. malayanum, E. revolutum, E. miyagawai) and Hypoderaeum conoideum (family Echinostomatidae) inferred from partial 28S rDNA sequence analysis
Authors: Hoa Le Thanh , Khanh Linh Pham Thi , Khue Nguyen Thi , Roan Do Thi , Kim Xuyen Le Thi , Thanh Huong Doan Thi
Published: August 2022

Echinostomiasis is a neglected disease caused by the intestinal flukes (family Echinostomatidae, suborder Echinostomata) and is common in communities in Asian countries, such as India, Indonesia, the Philippines, China, Malaysia, Singapore, Korea, Japan, Thailand, Laos, Cambodia and Vietnam. The genetic markers from the nuclear ribosomal transcription units are commonly used in genetic studies and phylogenetic analyses. A portion of the 28S rDNA sequence (domains D1–D3, of 1062–1067 bp for the final use) was obtained from the zoonotic Echinostoma malayanum (strain E/Amala-EMI3-TH), E. revolutum (strain Erevo-MSD15-TH), E. miyagawai (Emiya-RED11-TH), and Hypoderaeum conoideum (Hcono-RED42-TH) species; and used to perform an alignment for genetic distance estimation and phylogenetic analysis. The alignment was performed using 62 strains of 42 species from 19 genera of the family Echinostomatidae, including Echinoparyphium, Echinostoma, Artyfechinostomum, Patagifer, Neoacanthoparyphium, Hypoderaeum, Echinoparyphium, Drepanocephalus, Euparyphium, Chaunocephalus, Neopetasiger, Ribeiroia, Cathaemasia, Rhopalias, Isthmiophora, Petasiger, Moliniella, Pegosomum, and Schistosoma (family Schistosomatidae). The genetic distance estimation among 16 strains/10 species has shown a low intra-specific divergence level between strains within the same species, such as E. miyagawai (0–0.10%), E. revolutum (0.10–0.50%), and H. conoideum (0–0.10%), while between strains within the same genus it was higher (normally over 1.0%) and among strains/species between genera it was the highest (3.06–4.12%). The 28S rDNA sequence analysis and phylogenetic relationship well supported the Echinostoma/ Artyfechinostomum malayanum intergeneric taxonomy and the topology indicated clear, well-supported positions of member species in different genera in the family Echinostomatidae of the suborder Echinostomata. More sensu lato samples of the genera, are required for sequencing, particularly those of zoonotic species in the five genera: Artyfechinostomum, Echinostoma, Hypoderaeum, Echinoparyphium, and Isthmiophora. The resultant mitochondrial and nuclear data obtained from these species will be a good source to use to clearly assess the taxonomic and generic relationships.
Consciousness in Toni Morrison's Novel the Bluest Eye
Authors: Satyam S. , Prasad B. Bala Nagendra
Published: August 2022

Toni Morrison is the most well-known sophisticated novelist in the history of African American literature. She has been recognised as a strident voice for exploited black people as well as master craftsman of the dominant artistic form. The Bluest Eye is a tragic tale about a young,
black girl Pecola and her desire for the bluest eyes, the symbol for her of what it means to be beautiful and therefore worthy in society. It clarifies the damaging impacts of white standards and the importance on the lives of black people. It represents very sad feeling in terms of tragic
conditions of blacks in racist America. She investigates the devastating effects of the beauty standards of the dominant culture of the self-image of the African female adolescent. Exploring the complexity of black female experience in white America, Toni Morrison attempts to resolve the contradiction
inherent in her African American identity as a black women writer. In the novel The Bluest Eye it shows the terrible consequences for black internalising the values of a white culture that both directly & indirectly rejects them. A close study of the interrelationship of race, gender,
and class in the novels of Toni Morrison reveals the emergence of a revolutionary pattern. This paper attempts to find out the trial of the blacks women in search of self-identity in the novel of Toni Morrison.
A rational framework for post-flood road network condition recovery
Authors: Liang Pui Kay Patrick , Burrow Michael P N , Sasidharan Manu , Torbaghan Mehran Eskandari , Ghataora Gurmel S
Published: August 2022

Heavy-precipitation events can lead to widespread flooding and prolonged inundation of road pavement, which in turn would weaken its structural performance and accelerate its deterioration. A major challenge for road authorities is to prepare a suitable and swift recovery programme to restore the road network in the event of flood-related disruptions. Furthermore, widespread damage caused by flooding and other competing needs for recovery resources imposes additional constraints. The situation is exacerbated by the uncertainty and complexity of the post-flood situation. To address this challenge, a methodology for the formulation of a strategic post-flood pavement recovery programme based on life-cycle analysis is proposed in this paper. The resultant road conditions associated with the choice of work standards, the timing of implementation and funding constraints were evaluated in a case study, and a cost-effective recovery programme was formulated. The case study also demonstrated the use of output data to assist road authorities in strategic decision making. This study serves as a guide for road administration to develop a post-disaster recovery programme and provides insights for further research into post-disaster management of infrastructure systems.
Bonney’s Militant Poetics: Revolutionary Aesthetics, Politics and Black Poetics
Authors: Sharma-Patel Kashif
Published: August 2022

This essay looks at Sean Bonney’s relationship to the Black Radical Tradition, initially thinking of him as a bridge-like figure between the Marxist strains of the British Poetry Revival, and Black modernist poetics. Through looking at his relationship to Amiri Baraka, I interrogate the role of aesthetics and politics, and turn to Bonney’s conception of ‘militant poetics’. This links disparate formations within avant-garde aesthetics under the dialectic of Surrealism and Marxism where poetics synthesises creative and critical thought. Bonney’s work allows an opening of the apparent aporia between Black poetics and the British Poetry Revival, harnessing a subaltern trace in the structure of modernism, Marxism and politics which articulates a fractal subjectivity of sorts, which could be read along paraontological lines. Bonney’s engagement and embrace of Black poetics hints at an untetherable capacity for an embodied poetic practice, but a practice indicative of the wider structural faultlines of racial capitalism through the failed meeting of the British Poetry Revival and Black poetics. Bonney’s failure to engage with the Caribbean Artists Movement also raises questions around wider responsibilities of countercultural political aesthetics that operate across the revolutionary Black Atlantic.
How to obtain a copula from a process verb: Insights from the event structure of posture verbs
Authors: Gomez-Vazquez Diana , Mateu Jaume
Published: August 2022

Posture verbs (sit, stand, lie) seem to constitute an aspectual class of their own, as they do not readily fit the description of either states or activities. The contradicting results obtained from applying various diagnostic tests, which group posture verbs with either states or activities depending on the test’s sensitivity, have led to the creation of additional classes of states, namely, interval states (Dowty 1979) and Davidsonian states (Maienborn 2005), to account for the particular nature of the events denoted by these verbs. These approaches leave unanswered why equivalent verbs such as sentar ‘sit’ in Spanish, a Romance language, but also setzen ‘sit’ in German, a Germanic language, cannot denote stationary motion by themselves. This paper proposes that it is not necessary to introduce additional types of events to account for the lexical aspectual properties of posture verbs in English. Instead, it is their basic aspectual make-up, that is, their having a single process subevent (procP) (Ramchand 2008), and the labile nature of English that can explain their recalcitrant properties and the cross-linguistic issues they raise, while at the same time offering a seamless explanation for the propensity of posture verbs to become copulas cross-linguistically.
Literatura e afetividade nas redes durante a pandemia: uma análise das interações na “Quarentena Literária”
Authors: Thomé Cláudia de Albuquerque , Martins Vanessa Coutinho
Published: August 2022

O presente artigo traz resultados de pesquisa sobre o clube do livro virtual “Quarentena Literária”, da Editora Record, considerando que o isolamento social na pandemia reconfigurou possibilidades de interação na web. Busca-se verificar se a promessa de construção de laços se efetiva e categorizar as temáticas das interações, seguindo a Análise de Conteúdo de Bardin (2010). Conclui-se que não há manutenção de laços no ambiente, que dissipa seus participantes ao findar das transmissões.
Güncel Metasezgisel Algoritmalarla PID Ayarlama
Authors: VATANSEVER Fahri , HACIİSKENDEROGLU Emre
Published: August 2022

Uygulamalarda sistemlerin kontrolü son derece önemlidir. Bu amaçla uygun denetleyicilerin tasarlanması gerekmektedir. En popüler denetleyicilerin başında PID'ler gelmektedir ve bunların tasarımı için geleneksel yöntemler mevcuttur. Son yıllarda PID katsayılarının ayarlanması için metasezgisel algoritmalardan da faydalanılmaktadır. Gerçekleştirilen çalışmada PID türü denetleyicilerin tasarımını, farklı performans kriterlerine göre altı güncel metasezgisel algoritma ile yapan etkileşimli grafiksel kullanıcı arayüz programı tasarlanmıştır. Tekli veya karşılaştırmalı tasarımlar gerçekleştiren, sayısal ve grafiksel çözümler sunan, ayrıntılı analiz ve sentezlere olanak sağlayan bu yazılım aracıyla denetleyici katsayılarının ayarlanması kolay, hızlı ve etkin şekilde yapılabilmektedir.
Türkiye’deki Trombe Duvarı Sistemine ait Sayısal Isı Akışı Analizi
Authors: KAYA Ercan Şerif
Published: August 2022

Trombe duvarı, güneş enerjisinin depolanarak iç ortam sıcaklığının ilave enerji tüketimi gerektiren herhangi bir mekanik sisteme bağımlı kalmaksızın arttırılması için kullanılan pahalı olmayan bir pasif ısıtma sistemidir. Son zamanlarda ısı duvarının konfigürasyon ve enerji verimliliğine yönelik yapılan çalışmaların çoğu hesaplamalı akışkanlar dinamiği yardımıyla gerçekleştirilmiştir. Bunun sebeplerinden bir tanesi, bu programlarda cam ve akışkan alan çevresindeki yüzey sınır koşullarının temsil edildiği yarı geçirgen ve geçirimsiz duvarların kullanıcıya sağlanması ve enerjinin sadece yarı geçirgen duvarlar içerisinden geçebilmesine izin verilmesidir. Ancak, sonlu elemanlar metodu programlarında geçirimsiz duvar özelliklerine karşılık gelen ve enerjiyi ısı akışı şeklinde aktaran katı ve kabuk elemanlar kullanılabilmektedir. Bu çalışmada, daha önce deneysel bir çalışma kapsamında inşa edilmiş Trombe duvarı sistemine ait sayısal ısı akışı analizi gerçekleştirilmiş olup deneysel sonuçlarla doğrulanmıştır. Simülasyon çalışmalarına göre, güneş ışığı alması beklenen yüzeylere geçirimlilik katsayısına bağlı olarak hesaplanacak ilave güneş enerjisi tanımlanması halinde elde edilen sonuçların deneysel çalışmalarla örtüştüğü görülmüştür. Bununla birlikte, sayısal olarak doğrulanmış Trombe duvarı modelinin kullanılarak Türkiye’deki üç farklı iklim bölgesine ait konut yapılarındaki enerji tasarruf potansiyelinin değerlendirilmesine yönelik bir çalışma yapılmıştır.
High-throughput papain-based DNA extraction from whole invertebrates v1
Authors: Whittingham Rosa
Published: August 2022

This protocol is designed for extracting DNA from individual invertebrates in 96-well plate format for downstream barcoding or metabarcoding. The reagents and methods proposed offer a cost effective and high-throughput method for molecular identification, dietary analysis, parasitism diagnostics and more from individual invertebrate samples using standard lab equipment.
Biological sample lysis and extraction using the Covaris LE220+ for LC-MS v1
Authors: not provided ronan.ocualain
Published: August 2022

This protocol details the procedure of sample lysis and protein extraction using the Covaris LE220+ ultrasonicator.
PERAN PENDIDIKAN DAN PEMBERDAYAAN EKONOMI KELUARGA
Authors: Haryono Mas
Published: August 2022

Era globalisasi menuntut adanya sumber daya manusia (SDM) yang terampil, professional dan mampubersaing baik secara lokal, regional mapun internasional. Hal ini diiukti dengan adanya kemajuan yangsangat pesat di dalam bidang ilmu pengetahuan dan teknologi yang akan berdampak baik secara langsungmaupun tidak langsung terhadap dunia kerja. Sasaran program peningkatan mutu SDM diantaranyapada berbagai jenis keahlian dan keterampilan agar dapat membentuk manusia Indonesia yang terampildan siap bekerja sesuai dengan standar kompetensi tenaga kerja yang dibutuhkan.
KESIAPAN BELAJAR MANDIRI KONTRIBUSINYA PADA PRESTASI BELAJAR MATAKULIAH STENOGRAFI MAHAMAHASISWA ANGKATAN 2011 KLS A PADA PROGRAM STUDI PENDIDIKAN MANAJEMEN PERKANTORAN
Authors: Supardi Endang
Published: August 2022

Penelitian ini dilakukan pada Mahasiswa Angkatan 2011 Kls A  Pada  Program Studi Pendidikan Manajemen Perkantoran Universitas Pendidikan Indonesia.Permasalahan yang menjadi kajian dalam penelitian ini adalah rendahnya prestasi belajar stenografi Mahasiswa Angkatan 2011 Kls A  Pada  Program Studi Pendidikan Manajemen Perkantoran. Bukti empiris masalah tersebut dapat dilihat dari  rendahnya nilai ujian akhir semester (UAS) yang berada di bawah kriteria kelulusan. Nilai ini menjadi sebuah gambaran dan juga merupakan sebuah tolak ukur dalam tingkat keberprestasian belajar. Penelitian ini terdiri dari dua variabel yaitu minat kesiapan belajar mandiri (X) dan prestasi belajar mahasiswa (Y). Tujuan penelitian ini adalah untuk memperoleh  gambaran tingkat minat kesiapan belajar mandiri, tingkat prestasi belajar mahasiswa, dan juga untuk mengetahui apakah ada hubungan antara minat kesiapan belajar mandiri dengan prestasi belajar stenografi  Mahasiswa Pendidikan Manajemen Perkantoran Angkatan 2011 Kelas A.Metode yang digunakan dalam penelitian ini adalah laporan penelitian-verifikatif dengan  teknik survey, dengan teknik pengumpulan data melalui penyebaran angket, skala pengukuran yang digunakan yaitu ratting scale, angket dikumpulkan dari responden  dengan  ukuran populasi 47 Mahasiswa Angkatan 2011 Kls A  Pada  Program Studi Pendidikan Manajemen Perkantoran. Teknik analisis data yang digunakan dalam penelitian ini adalah uji koefiesien kontingensi.Berdasarkan prestasi penelitian, peneliti mendapatkan informasi bahwa tingkat minat kesiapan belajar mandiri berada pada kategori sedang dan tingkat prestasi belajar mahasiswa berada pada kategori sedang. Dari prestasi uji hipotesis diperoleh bahwa terdapat hubungan positf dan signifikan antara tingkat minat kesiapan belajar mandiri mahasiswa dengan tingkat prestasi belajar Mahasiswa Angkatan 2011 Kls A  Pada  Program Studi Pendidikan Manajemen Perkantoran
Motivasi Pengembangan Jiwa Kewirausahaan pada Mahasiswa (Langkah Strategi Pengembangan Usaha)
Authors: Aisyah S R Siti
Published: August 2022

Motivasi Pengembangan Jiwa Kewirausahaan pada Mahasiswa (Langkah Strategi Pengembangan Usaha)
Peranan Teknologi Informasi Pada Era Globalisai
Authors: Wardiana Wawan
Published: August 2022

Peranan Teknologi Informasi Pada Era Globalisai
Pengaruh Penempatan Terhadap Produktivitas Kerja Pegawai Administrasi
Authors: Suwatno Suwatno
Published: August 2022

Pengaruh Penempatan Terhadap Produktivitas Kerja Pegawai Administrasi
Pengaruh Internal Staffing dan Pelatihan Terhadap Prestasi Kerja Karyawan
Authors: Rofaida Rofi
Published: August 2022

Pengaruh Internal Staffing dan Pelatihan Terhadap Prestasi Kerja Karyawan
Front Matter Vol 6 No 1 Tahun 2007
Authors: Setiawan Yana
Published: August 2022

Front Matter Vol 6 No 1 Tahun 2007
Back Matter Vol 6 No 2 Tahun 2007
Authors: Setiawan Yana
Published: August 2022

Back Matter Vol 6 No 2 Tahun 2007
Komunikasi Pelayanan Prima Perpustakaan (Studi Kasus Pelayanan Prima Perpustakaan Universitas Bung Hatta Padang)
Authors: Sumartono Sumartono
Published: August 2022

Komunikasi Pelayanan Prima Perpustakaan (Studi Kasus Pelayanan Prima Perpustakaan Universitas Bung Hatta Padang)
Kelembagaan Hubungan Industrial dalam Penyelesaian Konfli Ketenagakerjaan Perusahaan Sebuah Tinjauan Komprehensif
Authors: Sontani Uep Tatang
Published: August 2022

Kelembagaan Hubungan Industrial dalam Penyelesaian Konfli Ketenagakerjaan Perusahaan Sebuah Tinjauan Komprehensif
Dysphemisms in English Literature of the XX Century. Modernist Tendency
Authors: Varfolomeev F.V. , Zenkevich I.V.
Published: August 2022

The following work is devoted to the study of dysphemisms in the modernist English literature of the XX century. The article examines some particular features of these means of language expression based on a specific literary material. The research is based on a selection of examples from sources, their contextual analysis, and the identification of dysphemisms. The provided information allows avoiding awkward situations during intercultural communication with native English speakers, translations and language learning, as well as familiarization with English literature to a certain extent.
The Role of Quality of Academic Information Systems and Facilities on Student Loyalty
Authors: Sianipar Milka Rositi , Pakpahan Efendy , Manalu Putranto
Published: August 2022

Abstract:  The growth of quality standards, as well as, higher student demands has implications for higher education to improve service quality to be able to provide satisfaction that leads to increased student loyalty.Research aims: This study determines the effect of academic information systems and facilities on student loyalty at the Faculty of Economics, Universitas Prima Indonesia through satisfaction as an integral variable.Design/Methodology/Approach: Data analysis using path analysis, and feasibility test of the model with the Smartpls 3.0 program. The population in this study were all 5th term students of Management Undergraduate Degree and Accounting Undergraduate Degree. The number of samples was determined using the Krejcie-Morgan table so that 291 people were selected.Research findings:  The results showed that the academic information system had a significant positive effect on student loyalty through satisfaction, so that the satisfaction variable  mediates the academic information system on student loyalty (t-statistic = 2.131 ( t-table): p-value = 0.034). Likewise, the effect of facilities on student loyalty through satisfaction as an intervening variable that shows a significant value (t-statistic = 2,220 ( t-table): p-value = 0.027).Theoretical contribution/Originality:. The novelty of this research is that increasing student loyalty can be done by improving academic information system services and adequate campus facilities.Practitioner/Policy implication:  The university management must provide quality facilities and infrastructure to increase student loyalty.
Vertodrom covering calculation and designing technology
Authors: Bieliatynskyi Andrii , Akmaldinova Oleksandra , Akmaldinova Victoria
Published: August 2022

The article is devoted to the analysis of existing methods of calculation of rigid heliport coverings, both domestic and foreign. Considerable attention is paid to the geometric dimensions in the plan and layout; location and orientation of heliports. Types of helipads are considered; materials used in the construction of heliports; type of structures (panels), designed for the construction of helicopter pads at the surface level (on any dense surface or ordinary soil), that successfully replace concrete, as well as for the reconstruction of worn and damaged concrete helicopter pads on rooftops and other heliport modifications; possible locations of helicopter pads, which may be different in size and configuration: mobile, off-road, ground, on the roofs of buildings and structures, on pontoons, on sea or river vessels and yachts, on offshore drilling platforms, by individual projects. Approaches to the improvement of the existing method of calculation and design of rigid helipads are analyzed.A comparative analysis of ICAO, FAA, SNiP 2.05.08-85 regulatory documentation and recommendations, which do not provide a clear idea of ​​the method of calculating the thickness of rigid heliports, do not separate the calculation of heliports from the calculation of aerodrome pavements, do not consider any critical cross sections in calculating the load from helicopters and the main differences in designing coverings for helicopters from those for aircraft maintenance, connected with the dynamics of the takeoff and landing operations.As the weight of modern helicopters varies widely, it has been established that different types of coverings must be used for different weight categories (from structures raised above the ground level for light and medium-weight helicopters to cement concrete coverings for heavy helicopters).
Місце гравюри у творчому доробку дизайнера-графіка Миколи Стратілата
Authors: Петрушевська Христина , Стратілат Микола
Published: August 2022

Досліджується творчий доробок професора Миколи Стратілата крізь призму етнодизайнерського світосприйняття на матеріалі його альбому “Поезія в образах”. Розглядаються попередні дослідження творчих здобутків митця. Наводяться основні факти з життя дизайнера-графіка, що безпосередньо пов’язані його розвитком як цілісної творчої особистості. Poзглядаються основні мотиви у творчості Народного художника України Миколи Стратілата. Проводиться системний аналіз символічно-образного підгрунтя, художніх засобів та технологічних особливостей, а також окремих робіт зі збірки “Поезія в образах”. Висвітлюється життєва та філософська позиція, які стали рушійною силою і роблять твори Миколи Стратілата такими самобутніми і неповторними. Підбиваються підсумки його творчих досягнень. Художником-дизайнером створено понад 500 станкових гравюр, майже 200 екслібрисів, проілюстровано близько 100 книг, він є автором акварелей, які стали знаковими в українському образотворчому мистецтві. У своїй творчості Микола Стратілат заперечує сумну дійсність не відвертим протестом, як це робили революційні шістдесятники, а утвердженням всього позитивного, доброго і гуманного в українському народі. Митець є справжнім героєм на ниві української культури та мистецтва, адже початок його творчості припадає на важкі часи радянського тоталітаризму, зневажання людяності, гідності та свободи. Творчість Миколи Стратілата отримала високу оцінку мистецтвознавців та вчених, таких, як професори Дмитро Степовик, Євген Антонович, академік Микола Жулинський, колег-художників Сергія Якутовича, Тетяни Голембієвської, Валерія Франчука та ін. Особливо Микола Стратілат відзначився, створюючи реконструкції архітектурних пам’яток України, за що і отримав почесне звання Народного художника України та нагороджений орденом святого архістратига Михаїла Української православної церкви Київського патріархату.Мета. Визначити місце творчого внеску в український етнодизайн ХХІ сторіччя Народного художника України Миколи Стратілата та провести системний аналіз графічно-ілюстративного матеріалу з точки зору дизайну книги на прикладі його творів з альбому « Поезія в образах».Методологія. У статті використано традиційні наукові методи історичного аналізу, порівняльного аналізу, метод системно-структурного аналізу.Результати. Досліджено книжкову ілюстрацію Миколи Стратілата, виокремлені основні риси його творчості.Наукова новизна. Вперше досліджується творчий доробок професора Миколи Стратілата крізь призму етнодизайнерського світосприйняття на матеріалі його альбому “Поезія в образах”.Практична значущість. Даний матеріал може бути використаний у культурно-освітньому процесі при підготовці дизайнерів-графіків.
ПОЛІКУЛЬТУРНА КОМПЕТЕНТНІСТЬ В СИСТЕМІ КОМПЕТЕНТНОСТЕЙ ОСОБИСТОСТІ
Authors: Кременчук Анна Сергіївна
Published: August 2022

У статті визначається місце полікультурної компетентності в системі компетентностей особистості, досліджується доцільність взаємозамінності понять «соціокультурний», «міжкультурний» та «полікультурний», а також доцільність віднесення полікультурної компетентності до складових комунікативної компетентності.
УДОСКОНАЛЕННЯ ПЕДАГОГІЧНОЇ МАЙСТЕРНОСТІ В УМОВАХ ЦИФРОВОЇ ТРАНСФОРМАЦІЇ ОСВІТИ
Authors: Ляхоцька Лариса Леонідівна , Науменко Тетяна Юхимівна
Published: August 2022

У статті розглянуто проблему удосконалення педагогічної майстерності викладача закладу освіти в умовах цифрової трансформації освітнього простору України.
ПРОФЕСІЙНЕ СТАНОВЛЕННЯ МАЙБУТНІХ КРИЗОВИХ ПСИХОЛОГІВ В УМОВАХ СУЧАСНОГО ЗАКЛАДУ ВИЩОЇ ОСВІТИ
Authors: Мельничук Тетяна Іванівна , Зубіашвілі Ірина Костянтинівна
Published: August 2022

У статті проаналізовані основні психологічні детермінанти процесу підготовки майбутніх кризових психологів. Досліджені результати теоретичного обґрунтування проблематики професійного становлення кризових психологів на час навчання їх у закладі вищої освіти. Розглянуто вважливість визначення якості освіти та вибору певних дисциплін для подальшої професійної реалізації майбутніх кризових психологів. Визначені основні компоненти підготовки психологів до діяльності їх в ситуаціях надзвичайних подій та кризових ситуацій.
МЕТОД ПРОЄКТІВ ЯК ІННОВАЦІЙНА ТЕХНОЛОГІЯ ПІДВИЩЕННЯ КВАЛІФІКАЦІЇ СОЦІАЛЬНИХ ПРАЦІВНИКІВ
Authors: Рудь Ксенія Вікторівна
Published: August 2022

У статті розглядається актуальність використання методу проєктів, як інноваційної технології підвищення кваліфікації соціальних працівників. Розглядаються види проєктів та їх переваги впровадження у процес навчання та розвитку.
ДОШКІЛЬНА ОСВІТА ЗА ПРИНЦИПОМ ТЕРИТОРІАЛЬНОЇ ДОСТУПНОСТІ: УКРАЇНСЬКІ РЕАЛІЇ ТА ПЕРСПЕКТИВИ
Authors: Сіткар Віктор Ілліч , Сіткар Степан Вікторович
Published: August 2022

У статті розглянуто деякі аспекти забезпечення територіальної доступності шкільної освіти в Україні починаючи із закладів дошкільної освіти. Розкрито естонський досвід реалізації цього принципу в закладах дошкільної освіти та гімназіях. Наголошується, що маленькі кроки можуть призвести до великих змін в освіті, зокрема діяльності місцевих територіальних громад, щодо стратегії безперервного навчання.
РЕЙТИНГ ЯК СУЧАСНА ТЕХНОЛОГІЯ ОЦІНЮВАННЯ РЕЗУЛЬТАТІВ НАВЧАННЯ СТУДЕНТІВ
Authors: Ямковий Олександр Юрійович , Ямкова Тетяна Андріївна
Published: August 2022

У статті здійснено порівняльний аналіз модульно-рейтингової системи оцінювання навчальних досягнень студентів та традиційної системи, що використовується нині в закладах фахової передвищої освіти.
Protocols of Standard of Care for Adult Patients with Primary Antibody Deficiencies Will Improve Timing of Diagnosis, Survival, and Quality of Life
Authors: Napiórkowska-Baran Katarzyna , Więsik-Szewczyk Ewa , Ziętkiewicz Marcin , Matyja-Bednarczyk Aleksandra , Kołtan Sylwia , Bąkowska-Kocik Natalia , Rosada Tomasz , Baranowska Karolina , Alska Ewa , Tykwińska Marta , Szynkiewicz Ewa , Zacniewski Robert , Bartuzi Zbigniew
Published: August 2022

The majority of primary immunodeficiencies (PIDs) are antibody deficiencies (PADs), and not all of them are rare diseases; As an example, Caucasian individuals suffer from selective IgA deficiency at a frequency of 1:500.In addition to infections, symptomatic patients with PAD are more likely to develop neoplastic, autoimmune, and allergic diseases. In the event that PAD is neglected or delayed for more than ten years, complications develop, eventually resulting in death. No studies have been conducted to devise and report detailed ready-to-use protocols for managing PAD to date.This study aimed to propose protocols and guidelines for the adult PAD patients’ standard care. Preparing the protocol, we considered the frequency and type of laboratory tests, imaging, endoscopic examinations, specialist consultations, and standardized recommendations for further care in the place of residence. As a result of the proposed monitoring scheme, patients can be provided with complete care in terms of their underlying conditions and comorbidities, as well as early detection of complications. This protocol will serve as a guide for physicians dealing with these patients and enable comparisons of patient groups across a variety of treatment centers, even far away from each other. A national consultant in the field of clinical immunology verified the protocol mainly developed by Polish experts from reference immunology centres for adults.
Influence of Vitamins A and D on the Expression of MicroRNA27-3p Isoforms and GATA3 in Experimental Autoimmune Encephalomyelitis
Authors: Mohammadi Kordkhayli Marziyeh , Mansouri Fatemeh , Talebi Farideh , Noorbakhsh Farshid , Saboor-Yaraghi Ali Akbar
Published: August 2022

Vitamins A, D, and microRNAs contribute to T cell differentiation into TH2 phenotypes. We investigated the molecular mechanisms and effects of vitamin A and D on the expression of GATA3 and miR-27-3p isoforms in experimental autoimmune encephalomyelitis (EAE) animal model of multiple sclerosis.
EAE was induced in C57BL/6 mice by immunization with myelin oligodendrocyte glycoprotein, mixed with Complete Freund's Adjuvant, together with injection of pertussis toxin. Treatments began one day before immunization with (200 μg and 100 ng of vitamin A and vitamin D per mouse, respectively, and vitamin A+D (100 μg+50 ng) per mouse. Expression levels of GATA3 and miR‑27‑3p isoforms were measured in the CNS and splenocytes by real-time RT-PCR.
The expression level of GATA3 in the mice spinal cords and splenocytes was increased in the vitamin A and A+D-treated EAE mice at 24 h and 48 h after restimulation by 10 µg and 40 µg of myelin oligodendrocyte glycoprotein. Vitamins A and D and their combination upregulated the miR-27-3p isoforms compared with EAE mice with no treatments. We also demonstrated that miR-273p isoform expression was altered in splenocytes of vitamin-treated EAE mice. The results showed a positive correlation between splenocyte GATA3 levels and miR-27-3p isoform expression.
The protective impacts of vitamins A and D in EAE mice may be mediated by the upregulation of GATA3. However, it is not specified whether suppression of GATA3-targeting miRNAs of the miR-27-3p family is involved in this effect. These results do not rule out the possibility that miR-27-3p isoforms might have beneficial effects by targeting other transcripts, such as GluA2 and NR2B.
The pros and cons of the second booster dose of the COVID-19 vaccine
Authors: Mostafavi Ehsan
Published: August 2022

The Article Abstract is not available.
First report of SPM metallo-β-lactamases producing Acinetobacter baumannii isolates in Morocco
Authors: Massik Abdelhamid , Hibaoui Lahbib , Moussa Benboubker , Yahyaoui Ghita , Oumokhtar Bouchra , Mahmoud Mustapha
Published: August 2022

Background and Objectives: Carbapenem-resistant Acinetobacter baumannii has recently been identified by the World Health Organization as a critical pathogen. We propose to characterize the molecular characteristics of clinical isolates of A. baumannii resistant to carbapenems collected in a Moroccan hospital.
Materials and Methods: Seventy carbapenem-resistant A. baumannii isolates from various samples were received at the mi- crobiology laboratory of the Hospital Center. Antibiotic susceptibility was tested by the diffusion disc method and molecular characterization of antimicrobial resistance was performed by PCR and sequencing.
Results: Carbapenemase genes were detected in our isolates: the OXA-51 gene and the ISbA1 sequence were detected in all isolates (100%), the OXA-23 and OXA-58 genes were detected in 82.85% and 10% of isolates respectively, MBL genes were dominated by VIM 39 isolates (55.7%), followed by GIM 26 isolates (37%), SIM 20 isolates (28.5%), IMP 8 isolates (11, 4%), NDM 3 isolates (4%) and for the first time in Morocco SPM with 4 isolates (5.7%).
Conclusion: The emergence of resistance of A. baumannii to carbapenems is a serious problem in our hospital which re- quires the establishment of a prevention strategy and strict respect for hygiene to minimize their dissemination.
Effect of eliminating hdcA gene of Staphylococcus epidermidis TYH1 on Histamine production
Authors: Pashangeh Safoora , Berizi Enayat , Majlesi Majid , Ghaderi Sajad , Nizet Victor , Dahesh Samira
Published: August 2022

Background and Objectives: The possible adverse effect of histamine on human health has made it a detrimental aspect to the quality and safety of many fermented food products especially fish sauce.
Materials and Methods: In the present study, hdcA gene in Staphylococcus epidermidis TYH1 was knocked out and its effect on histamine production was evaluated. HdcA encodes histidine decarboxylase, an enzyme that produces histamine from histidine. Both strains of TYH1, the wild type (WT) and mutant (∆hdcA) were then incubated in tryptic soy broth (TSB) supplemented with histidine (0.5 mM). The histamine content determined by capillary zone electrophoretic (CZE) analysis. Safety assessment of this mutant of food origin was conferred by virulence genes.
Results: It was found that S. epidermidis TYH1 exhibited production of histamine (50.09 ± 0.06 μg/mL), while ∆hdcA strain of TYH1 exhibited no histamine forming activity. Safety assessment of ∆hdcA revealed the presence of nuc gene, while superantigenic toxins and coa genes were not observed. Therefore, it has the ability to be used as a starter culture to decrease the histamine content in any fermented food products.
Conclusion: Our study findings may contribute to provide a novel approach of promoting the food safety of fish sauce and other fermented food products regarding the regulation of histamine content.
The mutations frequency of enhancer II/ HBx regions of hepatitis B virus in acutely infected Iranian patients: a cross-sectional study
Authors: Karami Chiman , Mollaei Hamidreza , Arabzadeh Seyed Alimohammad , Mazloum Jalali Kamyar , Amerkani Saman , Pashangzadeh Salar , Nikpour Najmeh
Published: August 2022

Background and Objectives: The viral transactivator HBx protein affect cellular, viral and pregenomic factors pathway. Mutations in this protein can produce new viruses with new antigenic determinants that are generally related to developing cancerous.
Materials and Methods: In this cross-sectional study, 33 serum samples of patients diagnosed with acute HBV infection were investigated for HBeAg and HBV DNA viral load and HBx gene mutations. mutation in the HBx protein detected by sequencing analysis.
Results: Out of the 33 samples, 19 samples were males (57.6%), and 14 samples were females. 15 (45.5%) were positive for HBx DNA and 18 patients were negative for HBx DNA (54.5%). After sequencing, three mutations were recognized in HBx at nucleotide positions 147, 148, and 391 that were stationed to G1524A, G1525A, and G1767C mutations.
Conclusion: The analysis result of this study shows G1524A and G1525A mutations that an important role in altering the inhibition function of the HBx activity domain. The G1767C mutation inactivates HBx transactivation activity. These muta- tions have a critical role in the pathogenicity of the virus, and the intensity of hepatic tissue demolition and the development of cirrhosis or carcinoma in patients can be understood.
Development of gold nanoparticles-lateral flow test as a novel field diagnostic assay for detecting foot-and-mouth disease and lumpy skin disease viruses
Authors: Abdalhamed Abeer Mostafa , Naser Soad Mohammed , Mohamed Ayman Hamady , Gamil Zeedan Gamil Sayed
Published: August 2022

Background and Objectives: Rapid diagnosis is a cornerstone for controlling and preventing viral disease outbreaks. The present study is aimed to develop a rapid field diagnostic test based on gold nanoparticles for the detection of lumpy skin diseases (LSD), and foot and mouth diseases (FMD) in animals with high sensitivity and specificity.
Materials and Methods: FMD and LSD vaccines were used as a source of viruses' antigens for preparing monoclonal anti- bodies and conjugated with gold nanoparticles that characterized using various techniques such as UV-visible spectrometry, and transmission electron microscopy (TEM).  Monoclonal antibodies (mAbs) for each serotype produced in experimental rats and used to capture antibodies for FMDV and /or LSDV. ELISA was used to screen 469 milk samples and 1165 serum samples from naturally infected cattle, buffaloes, sheep, and goats for validation of the lateral flow test (LFT). LSDV DNA was extracted from 117 blood and skin biopsy samples collected from naturally infected cattle during the 2019 outbreak.
Results: The specificity and sensitivity of GNP-LFT were evaluated and compared to Ag-ELISA, Western blot tests (WB), and PCR. A total of 95 FMDV positives out of 469 (20.25%) milk samples  and 268  FMDV positives out of 1165 (23.3%) serum samples from natural infected cattle, buffaloes, sheep, and goats examined by ELISA to valid GNPS-LFT Viral LSDV DNA was detected in 60/117 (51.5%) and 31/60 (52.9%). While the GNPS-LFT assay results were 49/117 (41.9%) and 29/60 (48.3%) blood and skin biopsy samples, respectively. The diagnostic sensitivity and specificity of the GNP-LFT test were 72% and 82%, respectively. All vesicular fluid and epithelium samples collected from infected animals were identified as positive by the GNP- LFT and Ag-ELISA. Ag-ELISA, on the other hand, was 90% and 100%. While the developed GNP- LFT used LSDV polyclonal antibodies were similar to ELISA and IgG-WB with a sensitivity of 72.8% and a specificity of 88.8%, respectively.
Conclusion: The GNPS-LFT is a novel immunoassay based on mono or polyclonal antibodies conjugated with gold nanopar- ticles that provides an accurate, rapid, specific, and sensitive tool for field rapid diagnosis of FMDV and LSDV.
Cosmologias racializadas: processos políticos e educativos anti(racistas) no ensino de Física e Astronomia
Authors: Alves-Brito Alan
Published: August 2022

Os modelos cosmológicos desenvolvidos pela Astronomia e pela Física são considerados fundamentais não apenas para a construção histórica do conceito moderno e contemporâneo de ciência, mas também como elementos fundantes da epistemologia vigente no campo da educação em ciências, ambos marcadamente brancos e eurocentrados. Este trabalho objetiva fazer uma discussão teórica, epistemológica e metodológica sobre como o uso do conceito de raça na produção do racismo e nos processos políticos e educativos anti(racistas) tem sido feito no contexto das Ciências Exatas, particularmente no caso de Física e de Astronomia. Por meio da categoria “cosmologias racializadas”, fazemos uma discussão teórica de como o conceito de raça e do racismo científico foram produzidos a partir do pensamento científico europeu do século XIX e têm sido reproduzidos na comunidade científica, em suas práticas políticas, educacionais e epistemológicas, de forma que o racismo científico, uma pseudociência, contribua para a afirmação de estereótipos e representações negativas do pensamento da população negra, contribuindo para a invisibilização e subalternização do lugar da produção do conhecimento sobre a África e o legado afrodiaspórico nas Ciências Exatas. Concluímos que as práticas e formas de pensar o Universo na perspectiva da Física e da Astronomia moderna e contemporânea são etnocêntricas e branconcêntricas, baseadas nos modelos europeus e dos Estados Unidos. Embora negado, as Ciências Exatas operam o tempo inteiro com o fenômeno do racismo, atualizado, perpetuado e legitimado pela ideia de raça, hierarquizando saberes e diferentes visões acerca da origem e evolução do Universo.
Casos de ensino na pesquisa e na formação de professores: entrevista com Maria da Graça Mizukami
Authors: Mendonça Luciana de Oliveira Souza
Published: August 2022

A entrevista com a educadora Maria da Graça Nicoletti Mizukami tem como foco temático casos de ensino na pesquisa e na formação de professores. Casos de ensino são narrativas de situações, reais ou não, abordando dilemas que permeiam o trabalho do professor na escola e na sala de aula ou mesmo em outras ocorrências de sua vida profissional. No Brasil, a Profa. Dra. Mizukami possui expressiva produção sobre casos de ensino, sua teorização, elaboração e uso na pesquisa e na formação de professores. Considerando sua trajetória de pesquisadora e de formadora, a entrevista focaliza seu encontro com esse instrumento, as principais referências teóricas, usos e aprendizados dessa experiência.
Caso de ensino: Vamos Quintanear? O encontro das crianças com o Poeta Passarinho
Authors: Rodrigues Adria Maria Ribeiro , Domingues Isa Mara Colombo Scarlati , Rocha Simone Albuquerque da
Published: August 2022

O artigo apresenta a narrativa em forma de caso de ensino sobre a prática leitora de uma professora com crianças do Ensino Fundamental, a partir da poética de Mário Quintana. O trabalho realizado considera a contribuição da literatura na tarefa de ajudar a criança a dar um novo sentido ao mundo por meio das palavras, e, sobretudo, possibilita a experiência estética e lúdica com a linguagem promovendo laços de afeto com a leitura. O objetivo é o de provocar os professores à reflexão a partir do caso de ensino que traz a possibilidade de uma prática leitora significativa e desafiadora, em que o texto literário é um aliado do professor no cotidiano da sala de aula. Adotados como estratégia investigativa e formativa, os casos de ensino e métodos de casos apresentam inúmeras possibilidades, entre elas o potencial formativo para o desenvolvimento profissional de professores a partir de uma narrativa que evidencia a prática potente de uma professora, capaz de promover experiências intensas mediadas por espaços de escuta sensível e diálogos com a obra de Mário Quintana. O caso de ensino concentra possibilidades de ensinar e aprender em processo de alteridade e alternância ao propiciar ao leitor da narrativa colocar-se no lugar de protagonista e com ele partilhar sua prática em um ethos de pertença.
A importância da participação no estudo de aula na formação continuada de professores que ensinam medidas nos anos iniciais
Authors: Pereira Sandro Augusto do Vale , Melo Gilberto Francisco Alves de
Published: August 2022

Os professores que ensinam matemática nos anos iniciais têm o desafio de ensinar conteúdos para os alunos que não apresentam, na maioria das vezes, domínio ou conhecimentos prévios suficientes para compreenderem determinado assunto, por exemplo, o objeto de estudo medidas. Além disso, os processos convencionais de formações docentes não têm dado conta dessa demanda. De um lado, porque não atendem às necessidades dos(as) professores(as), e do outro, porque não há participação ativa e reflexiva na construção/reconstrução dos saberes escolares. O presente artigo tem como objetivo defender as potencialidades e limites do Estudo de Aula, como possibilidade de formação continuada, tomando como referência, de modo específico, os seus colaboradores, os estudos desenvolvidos em Portugal e uma revisão da literatura sobre o tema, Estudo de Aula. Ou seja, um processo de formação continuada, o qual os(as) professores(as) planejem um objeto de estudo a ser desenvolvido e apresentem para os demais, e em seguida reflitam sobre o desenvolvimento da aula e sobre o que aprenderam, para que haja contribuições para a sua formação, sua prática profissional e sua produção/ressignificação de saberes. Compuseram o material de análise, como instrumentos de construção dos dados, o diário de campo com as observações de aulas, a produção coletiva (gravações e escritas) e entrevista semiestruturada. Por fim, com base nos resultados obtidos, permitiu-nos observar a necessidade que existe entre os docentes de aprimorar seus conhecimentos no conteúdo de medidas de comprimento e puderam compartilhar, por meio da formação continuada, dificuldades e compreensão do conteúdo trabalhado no processo formativo – medidas de comprimento, nos Anos Iniciais. O Estudo foi baseado no estudo de caso utilizando o Estudo de Aula, com a participação de professoras dos anos Iniciais.
O federalismo e as políticas de municipalização: um estudo sobre a educação básica em Xaxim (SC)
Authors: Trevisol Joviles Vitório , Silva Paulo Roberto da Silva
Published: August 2022

O presente artigo apresenta os resultados de uma pesquisa realizada entre 2017 e 2019 cujo propósito principal foi analisar os desdobramentos das políticas de municipalização da educação básica nos últimos trinta anos (1988-2018). Além das políticas em âmbito nacional e estadual, decidiu-se realizar um estudo numa unidade específica da federação. O estudo foi realizado no município de Xaxim, localizado na região Oeste de Santa Catarina, com população estimada em 28.424 habitantes. A pesquisa foi desenvolvida por meio de uma extensa revisão bibliográfica, análise documental e sistematização e análise de dados primários e secundários do município e da educação municipal disponíveis em diversas bases de dados. O estudo evidenciou que a partir da CF de 1988 o governo federal e o estado de Santa Catarina implementaram, de forma progressiva, uma série de políticas de descentralização de competências aos municípios. Tendo em vista esse conjunto de políticas, o município de Xaxim implementou inúmeras ações de expansão de sua rede municipal de ensino. Em 2018, a rede municipal respondia por 77% das matrículas do Ensino Fundamental e 72% de todas as matrículas da Educação Básica. Em 2018, a rede municipal respondia por 98% das matrículas das Creches; 97%, da Pré-escola; 77%, do Ensino Fundamental; 70%, da Educação Especial Exclusiva, e 62% da Educação de Jovens e Adultos. O município não oferta ensino médio. O estudo demonstrou também que a rede privada responde por apenas 3% do total das matrículas da educação básica.