bluuebunny/crossref_metadata_2025 huggingface dataset:
SV-4: Vertical reconstruction of P1 cells from A Distinct Oncogenerative Multinucleated Cancer Cell Serves as a Source of Stemness and Tumor Heterogeneity
Authors: Díaz-Carballo David , Saka Sahitya , Klein Jacqueline , Rennkamp Tobias , Acikelli Ali H. , Malak Sascha , Jastrow Holger , Wennemuth Gunther , Tempfer Clemens , Schmitz Inge , Tannapfel Andrea , Strumberg Dirk
Published: April 2023

P1 reconstruction in 3D vertical projection from TEM sections superposed. The inner structure of G1-containing cells is shown.
SV-2: P1 oncogenerative cells in parturient events from A Distinct Oncogenerative Multinucleated Cancer Cell Serves as a Source of Stemness and Tumor Heterogeneity
Authors: Díaz-Carballo David , Saka Sahitya , Klein Jacqueline , Rennkamp Tobias , Acikelli Ali H. , Malak Sascha , Jastrow Holger , Wennemuth Gunther , Tempfer Clemens , Schmitz Inge , Tannapfel Andrea , Strumberg Dirk
Published: April 2023

Oncogenerative P1 cells are giant cells with a syncytium-like morphology. This distinctive cell type complete cell life cycles which resemble lysogenic viral cycles. The mode of cellularization of the intracytoplasmically generated G1 cells (generation 1) is unique and takes place in different ways: a) in a lateral form which means that the G1 cells abandon the maternal P1 cells by trans cytoplasmic budding, b) through crevices formed with the participation of mitochondria around G1s until expulsion. After cellularization, the resulted aperture is filled by fusogenic HERV proteins, c) using a kind of funiculus or bridge connected to P1 maternal cells. An interesting process conducted by P1 cells is the horizontal transmission of G1 inoculating these cells into proximal receptor cells.
Figure S5 from Retinoic Acid–Related Orphan Receptor C Regulates Proliferation, Glycolysis, and Chemoresistance via the PD-L1/ITGB6/STAT3 Signaling Axis in Bladder Cancer
Authors: Cao Dalong , Qi Zihao , Pang Yangyang , Li Haoran , Xie Huyang , Wu Junlong , Huang Yongqiang , Zhu Yao , Shen Yijun , Zhu Yiping , Dai Bo , Hu Xin , Ye Dingwei , Wang Ziliang
Published: April 2023

Influence of RORC on the growth and proliferation of bladder cancer in vivo
A Containerized Software System for Generation, Management and Exploration of Features from Whole Slide Tissue Images from A Containerized Software System for Generation, Management, and Exploration of Features from Whole Slide Tissue Images
Authors: Saltz Joel , Sharma Ashish , Iyer Ganesh , Bremer Erich , Wang Feiqiao , Jasniewski Alina , DiPrima Tammy , Almeida Jonas S. , Gao Yi , Zhao Tianhao , Saltz Mary , Kurc Tahsin
Published: April 2023

Video describing the containerized Software System for Generation, Management and Exploration of Features from Whole Slide Tissue Images
Figure S3 from Retinoic Acid–Related Orphan Receptor C Regulates Proliferation, Glycolysis, and Chemoresistance via the PD-L1/ITGB6/STAT3 Signaling Axis in Bladder Cancer
Authors: Cao Dalong , Qi Zihao , Pang Yangyang , Li Haoran , Xie Huyang , Wu Junlong , Huang Yongqiang , Zhu Yao , Shen Yijun , Zhu Yiping , Dai Bo , Hu Xin , Ye Dingwei , Wang Ziliang
Published: April 2023

RORC Sensitizes Bladder Cancer Cells to Cisplatin
Table S2 from CDK8 Selectively Promotes the Growth of Colon Cancer Metastases in the Liver by Regulating Gene Expression of TIMP3 and Matrix Metalloproteinases
Authors: Liang Jiaxin , Chen Mengqian , Hughes Daniel , Chumanevich Alexander A. , Altilia Serena , Kaza Vimala , Lim Chang-Uk , Kiaris Hippokratis , Mythreye Karthikeyan , Pena Maria Marjorette , Broude Eugenia V. , Roninson Igor B.
Published: April 2023

List of PCR primers
Figure S5 from CDK8 Selectively Promotes the Growth of Colon Cancer Metastases in the Liver by Regulating Gene Expression of TIMP3 and Matrix Metalloproteinases
Authors: Liang Jiaxin , Chen Mengqian , Hughes Daniel , Chumanevich Alexander A. , Altilia Serena , Kaza Vimala , Lim Chang-Uk , Kiaris Hippokratis , Mythreye Karthikeyan , Pena Maria Marjorette , Broude Eugenia V. , Roninson Igor B.
Published: April 2023

Effects of Senexin B on the expression of different MMPs in a panel of human colon cancer cell lines and human colon cancer growth s.c.
Suppmental Data from Truncated Glioma-Associated Oncogene Homolog 1 (tGLI1) Mediates Mesenchymal Glioblastoma via Transcriptional Activation of CD44
Authors: Rimkus Tadas K. , Carpenter Richard L. , Sirkisoon Sherona , Zhu Dongqin , Pasche Boris C. , Chan Michael D. , Lesser Glenn J. , Tatter Stephen B. , Watabe Kounosuke , Debinski Waldemar , Lo Hui-Wen
Published: April 2023

This file contains Supplemental Figure 1 and Supplemental Tables I and II.
Figure S1 from CDK8 Selectively Promotes the Growth of Colon Cancer Metastases in the Liver by Regulating Gene Expression of TIMP3 and Matrix Metalloproteinases
Authors: Liang Jiaxin , Chen Mengqian , Hughes Daniel , Chumanevich Alexander A. , Altilia Serena , Kaza Vimala , Lim Chang-Uk , Kiaris Hippokratis , Mythreye Karthikeyan , Pena Maria Marjorette , Broude Eugenia V. , Roninson Igor B.
Published: April 2023

Supplemental data for effects of CDK8 inhibition on CT26 tumor growth.
Supplementary Methods and Figure Legends from Nuclear Receptor LRH-1 Functions to Promote Castration-Resistant Growth of Prostate Cancer via Its Promotion of Intratumoral Androgen Biosynthesis
Authors: Xiao Lijia , Wang Yuliang , Xu Kexin , Hu Hao , Xu Zhenyu , Wu Dinglan , Wang Zhu , You Wenxing , Ng Chi-Fai , Yu Shan , Chan Franky Leung
Published: April 2023

Supplementary Methods and Figure Legends
Supplementary Figures S1-S6 from Nuclear Receptor LRH-1 Functions to Promote Castration-Resistant Growth of Prostate Cancer via Its Promotion of Intratumoral Androgen Biosynthesis
Authors: Xiao Lijia , Wang Yuliang , Xu Kexin , Hu Hao , Xu Zhenyu , Wu Dinglan , Wang Zhu , You Wenxing , Ng Chi-Fai , Yu Shan , Chan Franky Leung
Published: April 2023

Supplementary Figures S1-S6
Supplementary Figure Legends and Table S1, S2, S3 from SWI/SNF-Compromised Cancers Are Susceptible to Bromodomain Inhibitors
Authors: Shorstova Tatiana , Marques Maud , Su Jie , Johnston Jake , Kleinman Claudia L. , Hamel Nancy , Huang Sidong , Alaoui-Jamali Moulay A. , Foulkes William D. , Witcher Michael
Published: April 2023

Table S1: List of shRNA plasmids. Table S2: List of primers S3: Mutations in ovarian and lung cancer cell lines.
Supplemental Table 1 from TumorMap: Exploring the Molecular Similarities of Cancer Samples in an Interactive Portal
Authors: Newton Yulia , Novak Adam M. , Swatloski Teresa , McColl Duncan C. , Chopra Sahil , Graim Kiley , Weinstein Alana S. , Baertsch Robert , Salama Sofie R. , Ellrott Kyle , Chopra Manu , Goldstein Theodore C. , Haussler David , Morozova Olena , Stuart Joshua M.
Published: April 2023

Supplemental Table 1A: Differential expression scores used in the pan-cancer cluster GSEA analysis. These scores represent integrated t-statistic scores from the differential analysis within each tissue (see Supplemental Methods). Supplemental Table 1B: Full results of the GSEA analysis of the pan-cancer cluster, based on differential expression scores. Supplemental Table 1C: Per-sample ESTIMATE scores used in analysis of the pan-cancer cluster. Supplemental Table 1D: Per-sample surrogate purity scores used in analysis of the pan-cancer cluster. Supplemental Table 1E: List of genes located on sex chromosomes that were excluded from the methylation dataset in order to analyze only autosomal gene features. Supplemental Table 1F: Attributes available in the TumorMap that annotate metadata of the samples, along with descriptions of those attributes. Supplemental Table 1G: Statistical tests computed by different attribute enrichment analysis (AEA) tools available in the TumorMap. Supplemental Table 1H: List of 82 samples in the pan-cancer cluster in the integrated map as well as tissue composition, along with the number of samples, in the integrated pan-cancer cluster. Supplemental Table 1I: Input data for the LAML survival analysis.
Figure S3 from SWI/SNF-Compromised Cancers Are Susceptible to Bromodomain Inhibitors
Authors: Shorstova Tatiana , Marques Maud , Su Jie , Johnston Jake , Kleinman Claudia L. , Hamel Nancy , Huang Sidong , Alaoui-Jamali Moulay A. , Foulkes William D. , Witcher Michael
Published: April 2023

Variable responses to epigenetic drugs
Supplemental Figure 4 from TumorMap: Exploring the Molecular Similarities of Cancer Samples in an Interactive Portal
Authors: Newton Yulia , Novak Adam M. , Swatloski Teresa , McColl Duncan C. , Chopra Sahil , Graim Kiley , Weinstein Alana S. , Baertsch Robert , Salama Sofie R. , Ellrott Kyle , Chopra Manu , Goldstein Theodore C. , Haussler David , Morozova Olena , Stuart Joshua M.
Published: April 2023

Enrichment of Immune signaling in the integrated pan-cancer cluster. Different level of evidence support the association of the integrated pan-cancer cluster with an immune phenotype. (A) Enrichment of T- and B-cell signaling shown on the integrated map, yellow gradient (see Supplemental Methods). (B) Enrichment of high ESTIMATE scores in the pan-cancer samples, waterfall plot with pan-cancer cluster samples in red. (C) Enrichment of the immune-related pathways identified by differential expression analysis. (D) Unsupervised analysis of master regulator activities inferred by the MARINa method. Gene clusters enriched for T- and B-cell signaling, interferon signaling, and TNFA via NFKB signaling, red font. (E) The top enriched pathways based on the output of master regulator scores derived with MARINa are immune-related. (F) Copy number events in the integrated pan-cancer cluster compared to other samples in the full cohort. The pan-cancer cluster shows a lower number of copy number events in both arm-level events and focal events. Arm-level events (pan-cancer group on the right, background cohort on the left). (G) Same as F but focal events (pan-cancer group on the right, background cohort on the left). (H) Purity estimates in the integrated pan-cancer cluster compared to all other samples in the cohort. The pan-cancer cluster (green box) shows lower purity when compared to the whole cohort as a background (yellow box). This finding is consistent with other analyses indicating high immune signaling in the pan-cancer cluster.
Supplemental Figure 3 from TumorMap: Exploring the Molecular Similarities of Cancer Samples in an Interactive Portal
Authors: Newton Yulia , Novak Adam M. , Swatloski Teresa , McColl Duncan C. , Chopra Sahil , Graim Kiley , Weinstein Alana S. , Baertsch Robert , Salama Sofie R. , Ellrott Kyle , Chopra Manu , Goldstein Theodore C. , Haussler David , Morozova Olena , Stuart Joshua M.
Published: April 2023

Tissue and molecular subtype distribution among the samples in the entire cohort (A-B), and in the pan-cancer cluster (C-D). The pie charts represent the number of samples from each tissue of origin in the entire cohort (A) and the integrated pan-cancer cluster (C). Black and white matrices illustrate the presence of molecular features of each platform (x-axis) across samples (y-axis), in the entire cohort (B) or in the integrated pan-cancer cluster (D). Data available for this sample for a given platform is marked black, otherwise the entry is white.
Figure S1 from SWI/SNF-Compromised Cancers Are Susceptible to Bromodomain Inhibitors
Authors: Shorstova Tatiana , Marques Maud , Su Jie , Johnston Jake , Kleinman Claudia L. , Hamel Nancy , Huang Sidong , Alaoui-Jamali Moulay A. , Foulkes William D. , Witcher Michael
Published: April 2023

Response of cancer cells to epigenetic targeting molecules
Supplementary Tables 1-6 from Genome-Wide Interrogation of Human Cancers Identifies EGLN1 Dependency in Clear Cell Ovarian Cancers
Authors: Price Colles , Gill Stanley , Ho Zandra V. , Davidson Shawn M. , Merkel Erin , McFarland James M. , Leung Lisa , Tang Andrew , Kost-Alimova Maria , Tsherniak Aviad , Jonas Oliver , Vazquez Francisca , Hahn William C.
Published: April 2023

Supplementary Tables 1-6. Supplementary Table 1 contains a list of constructs used in this manuscript. Tab 2 with Supplementary table 2 is a list of all six-sigma genes we identified. Supplementary table 3 contains EGLN1 CRISPR Associations with mutations, gene expression, CRISPR dependencies and copy number. Supplementary table 4 contains EGLN1 RNAi Associations with mutations, gene expression, RNAi dependencies and copy number. Supplementary Table 5 contains all cell line information and annotations used for this manuscript. Supplementary Table 6 contains RNA sequence data from EGLN1 KO cells and EGLN1 WT cells.
Supplementary Figures 1-7 from Genome-Wide Interrogation of Human Cancers Identifies EGLN1 Dependency in Clear Cell Ovarian Cancers
Authors: Price Colles , Gill Stanley , Ho Zandra V. , Davidson Shawn M. , Merkel Erin , McFarland James M. , Leung Lisa , Tang Andrew , Kost-Alimova Maria , Tsherniak Aviad , Jonas Oliver , Vazquez Francisca , Hahn William C.
Published: April 2023

Supplementary Figure 1 identifies EGLN1 as a cancer dependency in RNAi and CRISPR datasets and contains all significant associations. Supplementary Figure 2 is a lineage analysis of EGLN1 dependency within RNAi dataset. Supplementary Figure 3 is an immunoblot showing EGLN1 knockout in EGLN1-insensitive cell line. Supplementary Figure 4 shows pan-EGLN inhibition affects proliferation and apoptosis. Supplementary Figure 5 shows specific EGLN1 inhibitor IOX2 and VHL inhibitor VH298 inhibit proliferation. Supplementary Figure 6 shows differentially expressed genes in EGLN1-KO cells. Supplementary Figure 7 shows increased apoptosis in vivo when inhibiting EGLN1 or VHL.
Supplementary Fig 4 from YAP Suppresses Lung Squamous Cell Carcinoma Progression via Deregulation of the DNp63–GPX2 Axis and ROS Accumulation
Authors: Huang Hsinyi , Zhang Wenjing , Pan Yafang , Gao Yijun , Deng Lei , Li Fuming , Li Fei , Ma Xueyan , Hou Shenda , Xu Jing , Li Peixue , Li Xiaoxun , Hu Guohong , Li Cheng , Chen Haiquan , Zhang Lei , Ji Hongbin
Published: April 2023

Digitoxin treatment in mice doesn't result in significant weight loss and pathological or immunochemical changes.
Supplementary Fig 3 from YAP Suppresses Lung Squamous Cell Carcinoma Progression via Deregulation of the DNp63–GPX2 Axis and ROS Accumulation
Authors: Huang Hsinyi , Zhang Wenjing , Pan Yafang , Gao Yijun , Deng Lei , Li Fuming , Li Fei , Ma Xueyan , Hou Shenda , Xu Jing , Li Peixue , Li Xiaoxun , Hu Guohong , Li Cheng , Chen Haiquan , Zhang Lei , Ji Hongbin
Published: April 2023

YAP promotes ROS accumulation via the DNp63-GPX2 signaling axis
Supplementary Fig 2 from YAP Suppresses Lung Squamous Cell Carcinoma Progression via Deregulation of the DNp63–GPX2 Axis and ROS Accumulation
Authors: Huang Hsinyi , Zhang Wenjing , Pan Yafang , Gao Yijun , Deng Lei , Li Fuming , Li Fei , Ma Xueyan , Hou Shenda , Xu Jing , Li Peixue , Li Xiaoxun , Hu Guohong , Li Cheng , Chen Haiquan , Zhang Lei , Ji Hongbin
Published: April 2023

Negative correlation of YAP and P63 expression in human lung SCC.
Table S3 from Exosomes from Glioma-Associated Mesenchymal Stem Cells Increase the Tumorigenicity of Glioma Stem-like Cells via Transfer of miR-1587
Authors: Figueroa Javier , Phillips Lynette M. , Shahar Tal , Hossain Anwar , Gumin Joy , Kim Hoon , Bean Andrew J. , Calin George A. , Fueyo Juan , Walters Edgar T. , Kalluri Raghu , Verhaak Roel G. , Lang Frederick F.
Published: April 2023

MicroRNAs enriched in GA-MSC-derived exosomes down-regulate predicted gene targets in GSCs.
Table S1 from Exosomes from Glioma-Associated Mesenchymal Stem Cells Increase the Tumorigenicity of Glioma Stem-like Cells via Transfer of miR-1587
Authors: Figueroa Javier , Phillips Lynette M. , Shahar Tal , Hossain Anwar , Gumin Joy , Kim Hoon , Bean Andrew J. , Calin George A. , Fueyo Juan , Walters Edgar T. , Kalluri Raghu , Verhaak Roel G. , Lang Frederick F.
Published: April 2023

GA-hMSCs and GSCs exhibit stem cell-like characteristics.
Supplementary Figure Legends from KDM4 Inhibition Targets Breast Cancer Stem–like Cells
Authors: Metzger Eric , Stepputtis Stella S. , Strietz Juliane , Preca Bogdan-Tiberius , Urban Sylvia , Willmann Dominica , Allen Anita , Zenk Fides , Iovino Nicola , Bronsert Peter , Proske Amelie , Follo Marie , Boerries Melanie , Stickeler Elmar , Xu Jiangchun , Wallace Michael B. , Stafford Jeffrey A. , Kanouni Toufike , Maurer Jochen , Schüle Roland
Published: April 2023

This file contains the legends to all Supplementary Figures
Figure S5 from Exosomes from Glioma-Associated Mesenchymal Stem Cells Increase the Tumorigenicity of Glioma Stem-like Cells via Transfer of miR-1587
Authors: Figueroa Javier , Phillips Lynette M. , Shahar Tal , Hossain Anwar , Gumin Joy , Kim Hoon , Bean Andrew J. , Calin George A. , Fueyo Juan , Walters Edgar T. , Kalluri Raghu , Verhaak Roel G. , Lang Frederick F.
Published: April 2023

NCOR1 levels impact GSC proliferation.
Figure S4 from Exosomes from Glioma-Associated Mesenchymal Stem Cells Increase the Tumorigenicity of Glioma Stem-like Cells via Transfer of miR-1587
Authors: Figueroa Javier , Phillips Lynette M. , Shahar Tal , Hossain Anwar , Gumin Joy , Kim Hoon , Bean Andrew J. , Calin George A. , Fueyo Juan , Walters Edgar T. , Kalluri Raghu , Verhaak Roel G. , Lang Frederick F.
Published: April 2023

GA-hMSC-derived exosomes increase miRNA expression and impact miRNA target gene expression in GSCs.
Figure S6 from KDM4 Inhibition Targets Breast Cancer Stem–like Cells
Authors: Metzger Eric , Stepputtis Stella S. , Strietz Juliane , Preca Bogdan-Tiberius , Urban Sylvia , Willmann Dominica , Allen Anita , Zenk Fides , Iovino Nicola , Bronsert Peter , Proske Amelie , Follo Marie , Boerries Melanie , Stickeler Elmar , Xu Jiangchun , Wallace Michael B. , Stafford Jeffrey A. , Kanouni Toufike , Maurer Jochen , Schüle Roland
Published: April 2023

Treatment with QC6352 inhibits xenograft tumor growth of a second breast cancer stem cell line (BCSC2).
Figure S3 from Exosomes from Glioma-Associated Mesenchymal Stem Cells Increase the Tumorigenicity of Glioma Stem-like Cells via Transfer of miR-1587
Authors: Figueroa Javier , Phillips Lynette M. , Shahar Tal , Hossain Anwar , Gumin Joy , Kim Hoon , Bean Andrew J. , Calin George A. , Fueyo Juan , Walters Edgar T. , Kalluri Raghu , Verhaak Roel G. , Lang Frederick F.
Published: April 2023

GA-hMSC-derived exosomes do not contain growth factors or cytokines.
Figure S4 from KDM4 Inhibition Targets Breast Cancer Stem–like Cells
Authors: Metzger Eric , Stepputtis Stella S. , Strietz Juliane , Preca Bogdan-Tiberius , Urban Sylvia , Willmann Dominica , Allen Anita , Zenk Fides , Iovino Nicola , Bronsert Peter , Proske Amelie , Follo Marie , Boerries Melanie , Stickeler Elmar , Xu Jiangchun , Wallace Michael B. , Stafford Jeffrey A. , Kanouni Toufike , Maurer Jochen , Schüle Roland
Published: April 2023

Additional evidence showing control of EGFR expression by QC6352 is presented here. The specific EGFR inhibitor erlotinib diminishes proliferation and sphere formation in BCSC1 and BCSC2.
Figure S1 from Exosomes from Glioma-Associated Mesenchymal Stem Cells Increase the Tumorigenicity of Glioma Stem-like Cells via Transfer of miR-1587
Authors: Figueroa Javier , Phillips Lynette M. , Shahar Tal , Hossain Anwar , Gumin Joy , Kim Hoon , Bean Andrew J. , Calin George A. , Fueyo Juan , Walters Edgar T. , Kalluri Raghu , Verhaak Roel G. , Lang Frederick F.
Published: April 2023

Uptake of GA-hMSC-derived exosomes by GSCs.
Figure S1 from KDM4 Inhibition Targets Breast Cancer Stem–like Cells
Authors: Metzger Eric , Stepputtis Stella S. , Strietz Juliane , Preca Bogdan-Tiberius , Urban Sylvia , Willmann Dominica , Allen Anita , Zenk Fides , Iovino Nicola , Bronsert Peter , Proske Amelie , Follo Marie , Boerries Melanie , Stickeler Elmar , Xu Jiangchun , Wallace Michael B. , Stafford Jeffrey A. , Kanouni Toufike , Maurer Jochen , Schüle Roland
Published: April 2023

Characterization of the breast cancer stem cell line BCSC2 in vitro and in vivo. Like BCSC1 in Figure 1, BCSC2-derived xenografts also recapitulate the original patient tumor.
Figure S5 from Extracellular Matrix Protein Tenascin C Increases Phagocytosis Mediated by CD47 Loss of Function in Glioblastoma
Authors: Ma Ding , Liu Senquan , Lal Bachchu , Wei Shuang , Wang Shuyan , Zhan Daqian , Zhang Hao , Lee Richard S. , Gao Peisong , Lopez-Bertoni Hernando , Ying Mingyao , Li Jian Jian , Laterra John , Wilson Mary Ann , Xia Shuli
Published: April 2023

Figure S5 shows Arg-1 staining and quantification in xenografts from CD47 WT +/- TNC KD, and CD KO +/- TNC KD.
Supplementary Data from MITF Expression Predicts Therapeutic Vulnerability to p300 Inhibition in Human Melanoma
Authors: Kim Edward , Zucconi Beth E. , Wu Muzhou , Nocco Sarah E. , Meyers David J. , McGee Jean S. , Venkatesh Samantha , Cohen Daniel L. , Gonzalez Estela C. , Ryu Byungwoo , Cole Philip A. , Alani Rhoda M.
Published: April 2023

Supplemental Methods and Figure Legends
S1 from PDX-MI: Minimal Information for Patient-Derived Tumor Xenograft Models
Authors: Meehan Terrence F. , Conte Nathalie , Goldstein Theodore , Inghirami Giorgio , Murakami Mark A. , Brabetz Sebastian , Gu Zhiping , Wiser Jeffrey A. , Dunn Patrick , Begley Dale A. , Krupke Debra M. , Bertotti Andrea , Bruna Alejandra , Brush Matthew H. , Byrne Annette T. , Caldas Carlos , Christie Amanda L. , Clark Dominic A. , Dowst Heidi , Dry Jonathan R. , Doroshow James H. , Duchamp Olivier , Evrard Yvonne A. , Ferretti Stephane , Frese Kristopher K. , Goodwin Neal C. , Greenawalt Danielle , Haendel Melissa A. , Hermans Els , Houghton Peter J. , Jonkers Jos , Kemper Kristel , Khor Tin O. , Lewis Michael T. , Lloyd K.C. Kent , Mason Jeremy , Medico Enzo , Neuhauser Steven B. , Olson James M. , Peeper Daniel S. , Rueda Oscar M. , Seong Je Kyung , Trusolino Livio , Vinolo Emilie , Wechsler-Reya Robert J. , Weinstock David M. , Welm Alana , Weroha S. John , Amant Frédéric , Pfister Stefan M. , Kool Marcel , Parkinson Helen , Butte Atul J. , Bult Carol J.
Published: April 2023

A figure showing the process of generating and using PDX models.
Figure S2 from A Convolutional Neural Network Uses Microscopic Images to Differentiate between Mouse and Human Cell Lines and Their Radioresistant Clones
Authors: Toratani Masayasu , Konno Masamitsu , Asai Ayumu , Koseki Jun , Kawamoto Koichi , Tamari Keisuke , Li Zhihao , Sakai Daisuke , Kudo Toshihiro , Satoh Taroh , Sato Katsutoshi , Motooka Daisuke , Okuzaki Daisuke , Doki Yuichiro , Mori Masaki , Ogawa Kazuhiko , Ishii Hideshi
Published: April 2023

Figure S2
Supplemental Table (2) from Upregulation of Cystathionine-β-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis
Authors: Phillips Ches'Nique M. , Zatarain John R. , Nicholls Michael E. , Porter Craig , Widen Steve G. , Thanki Ketan , Johnson Paul , Jawad Muhammad U. , Moyer Mary P. , Randall James W. , Hellmich Judith L. , Maskey Manjit , Qiu Suimin , Wood Thomas G. , Druzhyna Nadiya , Szczesny Bartosz , Módis Katalin , Szabo Csaba , Chao Celia , Hellmich Mark R.
Published: April 2023

Gene Set Enrichment Analysis for NCM356 vector vs. CBS cells.
Supplemental Table (1) from Upregulation of Cystathionine-β-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis
Authors: Phillips Ches'Nique M. , Zatarain John R. , Nicholls Michael E. , Porter Craig , Widen Steve G. , Thanki Ketan , Johnson Paul , Jawad Muhammad U. , Moyer Mary P. , Randall James W. , Hellmich Judith L. , Maskey Manjit , Qiu Suimin , Wood Thomas G. , Druzhyna Nadiya , Szczesny Bartosz , Módis Katalin , Szabo Csaba , Chao Celia , Hellmich Mark R.
Published: April 2023

Single-nucleotide polymorphism analysis for NCM356 cells.
Supplemental Figure Legends from Upregulation of Cystathionine-β-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis
Authors: Phillips Ches'Nique M. , Zatarain John R. , Nicholls Michael E. , Porter Craig , Widen Steve G. , Thanki Ketan , Johnson Paul , Jawad Muhammad U. , Moyer Mary P. , Randall James W. , Hellmich Judith L. , Maskey Manjit , Qiu Suimin , Wood Thomas G. , Druzhyna Nadiya , Szczesny Bartosz , Módis Katalin , Szabo Csaba , Chao Celia , Hellmich Mark R.
Published: April 2023

Additional description of metabolic effects and effects of hydrogen sulfide on CBS overexpression in NCM356 cells.
Supplemental Figure (3) from Upregulation of Cystathionine-β-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis
Authors: Phillips Ches'Nique M. , Zatarain John R. , Nicholls Michael E. , Porter Craig , Widen Steve G. , Thanki Ketan , Johnson Paul , Jawad Muhammad U. , Moyer Mary P. , Randall James W. , Hellmich Judith L. , Maskey Manjit , Qiu Suimin , Wood Thomas G. , Druzhyna Nadiya , Szczesny Bartosz , Módis Katalin , Szabo Csaba , Chao Celia , Hellmich Mark R.
Published: April 2023

Effect of buthionine-sulfoximine (BSO) on growth of CBS2 and vector control cells.
Supplementary Figure 4 from Gemcitabine-Induced TIMP1 Attenuates Therapy Response and Promotes Tumor Growth and Liver Metastasis in Pancreatic Cancer
Authors: D'Costa Zenobia , Jones Keaton , Azad Abul , van Stiphout Ruud , Lim Su Y. , Gomes Ana L. , Kinchesh Paul , Smart Sean C. , Gillies McKenna W. , Buffa Francesca M. , Sansom Owen J. , Muschel Ruth J. , O'Neill Eric , Fokas Emmanouil
Published: April 2023

Supplementary Figure describing the impact of TIMP-1 on cell migration and invasion.
Supplementary Figure 3 from Gemcitabine-Induced TIMP1 Attenuates Therapy Response and Promotes Tumor Growth and Liver Metastasis in Pancreatic Cancer
Authors: D'Costa Zenobia , Jones Keaton , Azad Abul , van Stiphout Ruud , Lim Su Y. , Gomes Ana L. , Kinchesh Paul , Smart Sean C. , Gillies McKenna W. , Buffa Francesca M. , Sansom Owen J. , Muschel Ruth J. , O'Neill Eric , Fokas Emmanouil
Published: April 2023

Supplementary Figure showng Real time qPCR data on the expression of cytokines in-vitro.
Figure S6 from Elevated Heme Synthesis and Uptake Underpin Intensified Oxidative Metabolism and Tumorigenic Functions in Non–Small Cell Lung Cancer Cells
Authors: Sohoni Sagar , Ghosh Poorva , Wang Tianyuan , Kalainayakan Sarada Preeta , Vidal Chantal , Dey Sanchareeka , Konduri Purna Chaitanya , Zhang Li
Published: April 2023

Fig. S6 HSPs inhibit NSCLC cell proliferation in a dose-dependent manner. (A) The same doses of HSP1 and HSP2 that affect NSCLC cell lines (B-D) do not affect significantly the HBEC30KT cell lines representing normal lung epithelial cells. Data from representative NSCLC cell lines HCC4017 (B), H1299 (C), and A549 (D) are shown. For statistical analysis, the levels in treated cells were compared to the levels in untreated cells with a Welch 2-sample t-test. **, p-value < 0.005.
Figure S3 from Elevated Heme Synthesis and Uptake Underpin Intensified Oxidative Metabolism and Tumorigenic Functions in Non–Small Cell Lung Cancer Cells
Authors: Sohoni Sagar , Ghosh Poorva , Wang Tianyuan , Kalainayakan Sarada Preeta , Vidal Chantal , Dey Sanchareeka , Konduri Purna Chaitanya , Zhang Li
Published: April 2023

Fig. S3 (A) NSCLC cell lines exhibit a varying degree of migration capabilities. (B) NSCLC cell lines exhibit a varying degree of invasion capabilities. The images shown are cells that had migrated across Transwell inserts (in A) or had crossed invasion chambers coated with Corning Matrigel matrix and also passed Transwell inserts (in B). At least three independent experiments were carried out for every condition. Data are plotted as mean {plus minus} SD. For statistical analysis, the levels in NSCLC cells were compared to the levels in HCC cells with a Welch 2-sample t-test.*, p-value, 0.05, **, p-value < 0.005.
Table S5 from NK Cells Mediate Synergistic Antitumor Effects of Combined Inhibition of HDAC6 and BET in a SCLC Preclinical Model
Authors: Liu Yan , Li Yuyang , Liu Shengwu , Adeegbe Dennis O. , Christensen Camilla L. , Quinn Max M. , Dries Ruben , Han Shiwei , Buczkowski Kevin , Wang Xiaoen , Chen Ting , Gao Peng , Zhang Hua , Li Fei , Hammerman Peter S. , Bradner James E. , Quayle Steven N. , Wong Kwok-Kin
Published: April 2023

Innate immune response proteins identified via mass spectrometry
Table S1 from Genomic Status of MET Potentiates Sensitivity to MET and MEK Inhibition in NF1-Related Malignant Peripheral Nerve Sheath Tumors
Authors: Peacock Jacqueline D. , Pridgeon Matthew G. , Tovar Elizabeth A. , Essenburg Curt J. , Bowman Megan , Madaj Zachary , Koeman Julie , Boguslawski Elissa A. , Grit Jamie , Dodd Rebecca D. , Khachaturov Vadim , Cardona Diana M. , Chen Mark , Kirsch David G. , Maina Flavio , Dono Rosanna , Winn Mary E. , Graveel Carrie R. , Steensma Matthew R.
Published: April 2023

Summary of R26-MET transgene localization.
Supplementary video figure legend from A Novel Small-Molecule Inhibitor of MRCK Prevents Radiation-Driven Invasion in Glioblastoma
Authors: Birch Joanna L. , Strathdee Karen , Gilmour Lesley , Vallatos Antoine , McDonald Laura , Kouzeli Ariadni , Vasan Richa , Qaisi Abdulrahman Hussain , Croft Daniel R. , Crighton Diane , Gill Kathryn , Gray Christopher H. , Konczal Jennifer , Mezna Mokdad , McArthur Duncan , Schüttelkopf Alexander W. , McConnell Patricia , Sime Mairi , Holmes William M. , Bower Justin , McKinnon Heather J. , Drysdale Martin , Olson Michael F. , Chalmers Anthony J.
Published: April 2023

Supplementary video figure legend
Supplementary Tables from Molecular Subtype-Specific Immunocompetent Models of High-Grade Urothelial Carcinoma Reveal Differential Neoantigen Expression and Response to Immunotherapy
Authors: Saito Ryoichi , Smith Christof C. , Utsumi Takanobu , Bixby Lisa M. , Kardos Jordan , Wobker Sara E. , Stewart Kyle G. , Chai Shengjie , Manocha Ujjawal , Byrd Kevin M. , Damrauer Jeffrey S. , Williams Scott E. , Vincent Benjamin G. , Kim William Y.
Published: April 2023

Supplemental Table 1: Flow cytometry antibody information. Supplemental Table 2: List of genes (top 10% most differentially expressed genes) used to cluster mouse cell lines from Figure 3D. Supplemental Table 3: List of genes (top 10% most differentially expressed genes) used to cluster mouse cell line tumors from Figure 3E. Supplemntal Table 4. Class I predicted neoantigens. Supplemental Table 5. Class II predicted neoantigens
Supplementary Figure S4 from mTOR Inhibition via Displacement of Phosphatidic Acid Induces Enhanced Cytotoxicity Specifically in Cancer Cells
Authors: Nguyen Tra-Ly , Nokin Marie-Julie , Egorov Maxim , Tomé Mercedes , Bodineau Clément , Di Primo Carmelo , Minder Lætitia , Wdzieczak-Bakala Joanna , Garcia-Alvarez Maria Concepcion , Bignon Jérôme , Thoison Odile , Delpech Bernard , Surpateanu Georgiana , Frapart Yves-Michel , Peyrot Fabienne , Abbas Kahina , Terés Silvia , Evrard Serge , Khatib Abdel-Majid , Soubeyran Pierre , Iorga Bogdan I. , Durán Raúl V. , Collin Pascal
Published: April 2023

The file contains supplementary results showing that FRB domain of mTOR adopts different conformations in the apo form and in complex with ICSN3250 and PA.
Table S1 from Adoptive Immunotherapy Using PRAME-Specific T Cells in Medulloblastoma
Authors: Orlando Domenico , Miele Evelina , De Angelis Biagio , Guercio Marika , Boffa Iolanda , Sinibaldi Matilde , Po Agnese , Caruana Ignazio , Abballe Luana , Carai Andrea , Caruso Simona , Camera Antonio , Moseley Annemarie , Hagedoorn Renate S. , Heemskerk Mirjam H.M. , Giangaspero Felice , Mastronuzzi Angela , Ferretti Elisabetta , Locatelli Franco , Quintarelli Concetta
Published: April 2023

TABLE S1
Supplementary Figure S1 from mTOR Inhibition via Displacement of Phosphatidic Acid Induces Enhanced Cytotoxicity Specifically in Cancer Cells
Authors: Nguyen Tra-Ly , Nokin Marie-Julie , Egorov Maxim , Tomé Mercedes , Bodineau Clément , Di Primo Carmelo , Minder Lætitia , Wdzieczak-Bakala Joanna , Garcia-Alvarez Maria Concepcion , Bignon Jérôme , Thoison Odile , Delpech Bernard , Surpateanu Georgiana , Frapart Yves-Michel , Peyrot Fabienne , Abbas Kahina , Terés Silvia , Evrard Serge , Khatib Abdel-Majid , Soubeyran Pierre , Iorga Bogdan I. , Durán Raúl V. , Collin Pascal
Published: April 2023

The file contains supplementary results showing that ICSN3250 specifically inhibited mTORC1 pathway.
Video 1 from Long Noncoding RNA CRYBG3 Blocks Cytokinesis by Directly Binding G-Actin
Authors: Pei Hailong , Hu Wentao , Guo Ziyang , Chen Huaiyuan , Ma Ji , Mao Weidong , Li Bingyan , Wang Aiqing , Wan Jianmei , Zhang Jian , Nie Jing , Zhou Guangming , Hei Tom K.
Published: April 2023

Using a live cell imaging system showed cytokinesis and cell movement after overexpress of LNC NC.
Table S1 from Spliceosome Mutations Induce R Loop-Associated Sensitivity to ATR Inhibition in Myelodysplastic Syndromes
Authors: Nguyen Hai Dang , Leong Wan Yee , Li Weiling , Reddy Pavankumar N.G. , Sullivan Jack D. , Walter Matthew J. , Zou Lee , Graubert Timothy A.
Published: April 2023

List of primers used for RNA splicing assay
Supplemental Figure S8 from Therapeutically Active RIG-I Agonist Induces Immunogenic Tumor Cell Killing in Breast Cancers
Authors: Elion David L. , Jacobson Max E. , Hicks Donna J. , Rahman Bushra , Sanchez Violeta , Gonzales-Ericsson Paula I. , Fedorova Olga , Pyle Anna M. , Wilson John T. , Cook Rebecca S.
Published: April 2023

4T1 cells were transfected with SLR20 or OH-SLR20. At 4 hours after transfection, 4T1 cells were washed 5 times, then cultured in serum-free media for 16 hours. 4T1-cultured supernatant was collected, passed through a 0.2ï�­m filter, then added neat to cultures of Raw264.7 cells for 30 minutes. Western analysis of RAW264.7 whole cell lysates was used to measure P-STAT1. Cells were transfected, and after 16 h, total RNA was assessed by RT-qPCR to measure expression of the indicated gene.. Each point represents the average of three experimental replicates, N = 3. Midlines are average {plus minus} S.D. Student's T-test.
Supplemental Figure S4 from Therapeutically Active RIG-I Agonist Induces Immunogenic Tumor Cell Killing in Breast Cancers
Authors: Elion David L. , Jacobson Max E. , Hicks Donna J. , Rahman Bushra , Sanchez Violeta , Gonzales-Ericsson Paula I. , Fedorova Olga , Pyle Anna M. , Wilson John T. , Cook Rebecca S.
Published: April 2023

Immunohistochemistry was used to measure Ki67 and TUNEL+ cells in tumors harvested at day 5. Representative Images are shown. N = 5. Immunohistochemistry was used to measure Ki67 and TUNEL+ cells in tumors harvested at day 5. Representative Images are shown. N = 5. Western analysis of whole cell lysates collected 16 hours after transfection using antibodies indicated at the left of each panel. MCF7 Cells were transfected, and after 16 h, total RNA was assessed by RT-qPCR to measure expression of the indicated genes involved in pyroptosis. Each point represents the average of three experimental replicates, N = 3. Midlines are average {plus minus} S.D. Student's T-test.
List of SCC SUVmax correlated genes from GFPT2-Expressing Cancer-Associated Fibroblasts Mediate Metabolic Reprogramming in Human Lung Adenocarcinoma
Authors: Zhang Weiruo , Bouchard Gina , Yu Alice , Shafiq Majid , Jamali Mehran , Shrager Joseph B. , Ayers Kelsey , Bakr Shaimaa , Gentles Andrew J. , Diehn Maximilian , Quon Andrew , West Robert B. , Nair Viswam , van de Rijn Matt , Napel Sandy , Plevritis Sylvia K.
Published: April 2023

This supplement file contains the identified SUVmax correlated genes in the lung squamous cell carcinoma patients in the RG cohort.
List of AD SUVmax-correlated genes from GFPT2-Expressing Cancer-Associated Fibroblasts Mediate Metabolic Reprogramming in Human Lung Adenocarcinoma
Authors: Zhang Weiruo , Bouchard Gina , Yu Alice , Shafiq Majid , Jamali Mehran , Shrager Joseph B. , Ayers Kelsey , Bakr Shaimaa , Gentles Andrew J. , Diehn Maximilian , Quon Andrew , West Robert B. , Nair Viswam , van de Rijn Matt , Napel Sandy , Plevritis Sylvia K.
Published: April 2023

This supplement file contains the identified SUVmax correlated genes in the lung adenocarcinoma patients in the RG cohort.
Figure S6 from YAP1-Mediated Suppression of USP31 Enhances NFκB Activity to Promote Sarcomagenesis
Authors: Ye Shuai , Lawlor Matthew A. , Rivera-Reyes Adrian , Egolf Shaun , Chor Susan , Pak Koreana , Ciotti Gabrielle E. , Lee Avery C. , Marino Gloria E. , Shah Jennifer , Niedzwicki David , Weber Kristy , Park Paul M.C. , Alam Md. Zahidul , Grazioli Alison , Haldar Malay , Xu Mousheng , Perry Jennifer A. , Qi Jun , Eisinger-Mathason T.S. Karin
Published: April 2023

The role of AMOT in sarcomagenesis
Figure S3 from Plk1-Mediated Phosphorylation of TSC1 Enhances the Efficacy of Rapamycin
Authors: Li Zhiguo , Kong Yifan , Song Longzhen , Luo Qian , Liu Jinghui , Shao Chen , Hou Xianzeng , Liu Xiaoqi
Published: April 2023

Cells expressing different forms of TSC1 (2A or 2E) have different mTORC1 activities
Figure S1 from Plk1-Mediated Phosphorylation of TSC1 Enhances the Efficacy of Rapamycin
Authors: Li Zhiguo , Kong Yifan , Song Longzhen , Luo Qian , Liu Jinghui , Shao Chen , Hou Xianzeng , Liu Xiaoqi
Published: April 2023

Inhibition of mTORC1, but not PI3K, prevents mitosis-associated S6 phosphorylation
Supplementary Data from EWS/ETS-Driven Ewing Sarcoma Requires BET Bromodomain Proteins
Authors: Gollavilli Paradesi Naidu , Pawar Aishwarya , Wilder-Romans Kari , Natesan Ramakrishnan , Engelke Carl G. , Dommeti Vijaya L. , Krishnamurthy Pranathi M. , Nallasivam Archana , Apel Ingrid J. , Xu Tianlei , Qin Zhaohui S. , Feng Felix Y. , Asangani Irfan A.
Published: April 2023

Supplementary Data from EWS/ETS-Driven Ewing Sarcoma Requires BET Bromodomain Proteins
Figure S2 from Semaphorin 7A Promotes Macrophage-Mediated Lymphatic Remodeling during Postpartum Mammary Gland Involution and in Breast Cancer
Authors: Elder Alan M. , Tamburini Beth A.J. , Crump Lyndsey S. , Black Sarah A. , Wessells Veronica M. , Schedin Pepper J. , Borges Virginia F. , Lyons Traci R.
Published: April 2023

Macrophage gating strategy and chemoattractant expression levels
Figure S1 from Semaphorin 7A Promotes Macrophage-Mediated Lymphatic Remodeling during Postpartum Mammary Gland Involution and in Breast Cancer
Authors: Elder Alan M. , Tamburini Beth A.J. , Crump Lyndsey S. , Black Sarah A. , Wessells Veronica M. , Schedin Pepper J. , Borges Virginia F. , Lyons Traci R.
Published: April 2023

LYVE-1 expression during involution
Data File S2 from Dose and Schedule Determine Distinct Molecular Mechanisms Underlying the Efficacy of the p53–MDM2 Inhibitor HDM201
Authors: Jeay Sébastien , Ferretti Stéphane , Holzer Philipp , Fuchs Jeanette , Chapeau Emilie A. , Wartmann Markus , Sterker Dario , Romanet Vincent , Murakami Masato , Kerr Grainne , Durand Eric Y. , Gaulis Swann , Cortes-Cros Marta , Ruetz Stephan , Stachyra Therese-Marie , Kallen Joerg , Furet Pascal , Würthner Jens , Guerreiro Nelson , Halilovic Ensar , Jullion Astrid , Kauffmann Audrey , Kuriakose Emil , Wiesmann Marion , Jensen Michael R. , Hofmann Francesco , Sellers William R.
Published: April 2023

Median of the shRNAs and RSA values. File containing median counts and log fold changes of each gene from Supplementary Data File S1. According significance values of each gene as activator or sensitizer compared to DMSO control (see Methods) are included.
Supplementary Figure 5 from Extracorporeal Photochemotherapy Drives Monocyte-to-Dendritic Cell Maturation to Induce Anticancer Immunity
Authors: Ventura Alessandra , Vassall Aaron , Robinson Eve , Filler Renata , Hanlon Douglas , Meeth Katrina , Ezaldein Harib , Girardi Michael , Sobolev Olga , Bosenberg Marcus W. , Edelson Richard L.
Published: April 2023

Additional data for Figure 3, showing representative tumor growth data with tumor volumes to complement Figure 3A, as well as the full panel of soluble analytes examined by Luminex, to complement Figure 3C and D, for review and publication
Table S7 from Computational Characterization of Suppressive Immune Microenvironments in Glioblastoma
Authors: Luoto Suvi , Hermelo Ismaïl , Vuorinen Elisa M. , Hannus Paavo , Kesseli Juha , Nykter Matti , Granberg Kirsi J.
Published: April 2023

Tables contain immune subgroup for each sample and results from statistical testing for all probes from Illumina Infinium Human DNA Methylation 450 array. Statistical testing was done between the following sample groups: IDH1 mutated sampels; IDH1 wild type samples with CDK4-MARCH9 locus amplification; Other IDH1 wild type samples.
Table S4 from Computational Characterization of Suppressive Immune Microenvironments in Glioblastoma
Authors: Luoto Suvi , Hermelo Ismaïl , Vuorinen Elisa M. , Hannus Paavo , Kesseli Juha , Nykter Matti , Granberg Kirsi J.
Published: April 2023

Tables contain results from Ingenuity Pathway Analysis for immune system related gene clusters.
Supplementary Tables (S1-S5) from An ATM/TRIM37/NEMO Axis Counteracts Genotoxicity by Activating Nuclear-to-Cytoplasmic NF-κB Signaling
Authors: Wu Geyan , Song Libing , Zhu Jinrong , Hu Yameng , Cao Lixue , Tan Zhanyao , Zhang Shuxia , Li Ziwen , Li Jun
Published: April 2023

Supplementary Tables to support primary figures
Supplementary Figures (S1-S5) from An ATM/TRIM37/NEMO Axis Counteracts Genotoxicity by Activating Nuclear-to-Cytoplasmic NF-κB Signaling
Authors: Wu Geyan , Song Libing , Zhu Jinrong , Hu Yameng , Cao Lixue , Tan Zhanyao , Zhang Shuxia , Li Ziwen , Li Jun
Published: April 2023

Supplementary Figure S1 shows that TRIM37 promotes genotoxic stress-induced NF-κB activation. Supplementary Figure S2 shows TRIM37 promotes NEMO monoubiquitination at residue K309. Supplementary Figure S3 shows Genotoxic stress induces TRIM37 nuclear translocation and association with NEMO. Supplementary Figure S4 shows TRAF6 is required for TRIM37-induced NEMO monoubiquitination. Supplementary Figure S5 shows TRAF6-binding motif and Ring finger domain of TRIM37 is essential for the interaction with TRAF6.
Figure S5 from Loss of MED12 Induces Tumor Dormancy in Human Epithelial Ovarian Cancer via Downregulation of EGFR
Authors: Luo Xiao-Lin , Deng Cheng-Cheng , Su Xiao-Dong , Wang Fang , Chen Zhen , Wu Xing-Ping , Liang Shao-Bo , Liu Ji-Hong , Fu Li-Wu
Published: April 2023

MED12 KO could decrease the expression of MED13, Cyclin C and CDK8.
Figure S3 from Loss of MED12 Induces Tumor Dormancy in Human Epithelial Ovarian Cancer via Downregulation of EGFR
Authors: Luo Xiao-Lin , Deng Cheng-Cheng , Su Xiao-Dong , Wang Fang , Chen Zhen , Wu Xing-Ping , Liang Shao-Bo , Liu Ji-Hong , Fu Li-Wu
Published: April 2023

EGFR knock-down decreased the proliferation and sphere formation of SKOV3 cells.
Supplementary Fig S5 from Mucosal HPV E6/E7 Peptide Vaccination in Combination with Immune Checkpoint Modulation Induces Regression of HPV+ Oral Cancers
Authors: Dorta-Estremera Stephanie , Chin Renee L. , Sierra Gloria , Nicholas Courtney , Yanamandra Ananta V. , Nookala Sita M.K. , Yang Guojun , Singh Shail , Curran Michael A. , Sastry K. Jagannadha
Published: April 2023

Durability of tumor regression in mice treated with vaccine, a4-1BB and aCD40
Supplementary Fig S2 from Mucosal HPV E6/E7 Peptide Vaccination in Combination with Immune Checkpoint Modulation Induces Regression of HPV+ Oral Cancers
Authors: Dorta-Estremera Stephanie , Chin Renee L. , Sierra Gloria , Nicholas Courtney , Yanamandra Ananta V. , Nookala Sita M.K. , Yang Guojun , Singh Shail , Curran Michael A. , Sastry K. Jagannadha
Published: April 2023

Sequential treatment of vaccine and immune checkpoint modulation
Table S1 from Pharmacologic Ascorbate Reduces Radiation-Induced Normal Tissue Toxicity and Enhances Tumor Radiosensitization in Pancreatic Cancer
Authors: Alexander Matthew S. , Wilkes Justin G. , Schroeder Samuel R. , Buettner Garry R. , Wagner Brett A. , Du Juan , Gibson-Corley Katherine , O’Leary Brianne R. , Spitz Douglas R. , Buatti John M. , Berg Daniel J. , Bodeker Kellie L. , Vollstedt Sandy , Brown Heather A. , Allen Bryan G. , Cullen Joseph J.
Published: April 2023

Radiation induced intestinal damage histology and collagen deposition information.
Figure S3 from Targeting CCR8 Induces Protective Antitumor Immunity and Enhances Vaccine-Induced Responses in Colon Cancer
Authors: Villarreal Daniel O. , L'Huillier Andrew , Armington Susan , Mottershead Cristina , Filippova Elena V. , Coder Brandon D. , Petit Robert G. , Princiotta Michael F.
Published: April 2023

Expression of Lm-AH1 vaccine construct.
Figure S3 from Cyclophilin A Function in Mammary Epithelium Impacts Jak2/Stat5 Signaling, Morphogenesis, Differentiation, and Tumorigenesis in the Mammary Gland
Authors: Volker Sonja E. , Hedrick Shannon E. , Feeney Yvonne B. , Clevenger Charles V.
Published: April 2023

Immunohistochemistry of CypA+/+ and CypA-/- wk 14 virgins
Figure S6 from Paclitaxel Reduces Tumor Growth by Reprogramming Tumor-Associated Macrophages to an M1 Profile in a TLR4-Dependent Manner
Authors: Wanderley Carlos W. , Colón David F. , Luiz João Paulo M. , Oliveira Francisco F. , Viacava Paula R. , Leite Caio A. , Pereira Janaina A. , Silva Camila M. , Silva Cassia R. , Silva Rangel L. , Speck-Hernandez Cesar A. , Mota José M. , Alves-Filho José C. , Lima-Junior Roberto C. , Cunha Thiago M. , Cunha Fernando Q.
Published: April 2023

Gating strategy for flow cytometry analysis
Supplementary Tables S3 and S4 from Neonatal Inflammatory Markers Are Associated with Childhood B-cell Precursor Acute Lymphoblastic Leukemia
Authors: Søegaard Signe Holst , Rostgaard Klaus , Skogstrand Kristin , Wiemels Joseph Leo , Schmiegelow Kjeld , Hjalgrim Henrik
Published: April 2023

Intra and inter assay variations and correlation matrix of the inflammatory markers.
Supplementary Table S2 from Targeting STAT5 or STAT5-Regulated Pathways Suppresses Leukemogenesis of Ph+ Acute Lymphoblastic Leukemia
Authors: Minieri Valentina , De Dominici Marco , Porazzi Patrizia , Mariani Samanta A. , Spinelli Orietta , Rambaldi Alessandro , Peterson Luke F. , Porcu Pierluigi , Nevalainen Marja T. , Calabretta Bruno
Published: April 2023

Primary human Ph-like sample
Supplementary Table S9 from Neonatal Inflammatory Markers Are Associated with Childhood B-cell Precursor Acute Lymphoblastic Leukemia
Authors: Søegaard Signe Holst , Rostgaard Klaus , Skogstrand Kristin , Wiemels Joseph Leo , Schmiegelow Kjeld , Hjalgrim Henrik
Published: April 2023

Association between neonatal inflammatory markers and risk of infections before age 2 years.
Figure S1-7,Table S1-3 from IL22RA1/STAT3 Signaling Promotes Stemness and Tumorigenicity in Pancreatic Cancer
Authors: He Weizhi , Wu Jinghua , Shi Juanjuan , Huo Yan-Miao , Dai Wentao , Geng Jing , Lu Ping , Yang Min-Wei , Fang Yuan , Wang Wei , Zhang Zhi-Gang , Habtezion Aida , Sun Yong-Wei , Xue Jing
Published: April 2023

Figure S1.Flow cytometry analysis of IL-22RA1 expression among PDAC; Figure S2. The correlation analyses between IL-22RA1 and CSCs Figure S3. IL-22RA1hi pancreatic cancer cells have CSCs properties Figure S4. IL-22RA1hi pancreatic cancer cells express higher EMT markers FigureS5. IL-22 promotes stemness of pancreatic cancer cells FigureS6. IL-6 activates STAT3, but unable to promote stemness of PDACs Figure S7. Dot1L is not involved in IL-22 induced stemness of PDACs Table S1. Quantitative real-time PCR and ChIP primers TableS2&3. The co-relationship between IL-22RA1 expression and PDAC patients characteristics
Figure S1-S6 from Network Modeling of microRNA–mRNA Interactions in Neuroblastoma Tumorigenesis Identifies miR-204 as a Direct Inhibitor of MYCN
Authors: Ooi Chi Yan , Carter Daniel R. , Liu Bing , Mayoh Chelsea , Beckers Anneleen , Lalwani Amit , Nagy Zsuzsanna , De Brouwer Sara , Decaesteker Bieke , Hung Tzong-Tyng , Norris Murray D. , Haber Michelle , Liu Tao , De Preter Katleen , Speleman Frank , Cheung Belamy B. , Marshall Glenn M.
Published: April 2023

This file contains Supplementary Figure legends and Figures Supplementary Figure 1 - Comparisons between time-dependent gene expression quantification models Supplementary Figure 2 - Comparisons of Piscore for miRNA and mRNA members of interaction hubs Supplementary Figure 3 - Survival metrics for miRNA and miRNA signature in human neuroblastoma tumors Supplementary Figure 4 - Gene set enrichment analysis of predicted miR204 target genes upon MYCN siRNA treatment Supplementary Figure 5 - Data to support the creation of dox-inducible miR204 expressing cells and to support miR204 MYCN relationship Supplementary Figure 6 - Data to support miR204 effects on MYCN expression, neuroblastoma proliferation and xenograft experiments.