bluuebunny/crossref_metadata_2025 huggingface dataset:
Genetic and Epigenetic Profiling Reveals EZH2-mediated Down Regulation of OCT-4 Involves NR2F2 during Cardiac Differentiation of Human Embryonic Stem Cells
Authors: Pursani Varsha , Pethe Prasad , Bashir Mohsin , Sampath Prabha , Tanavde Vivek , Bhartiya Deepa
Published: October 2017

Human embryonic (hES) stem cells are widely used as an in vitro model to understand global genetic and epigenetic changes that occur during early embryonic development. In-house derived hES cells (KIND1) were subjected to directed differentiation into cardiovascular progenitors (D12) and beating cardiomyocytes (D20). Transcriptome profiling of undifferentiated (D0) and differentiated (D12 and 20) cells was undertaken by microarray analysis. ChIP and sequential ChIP were employed to study role of transcription factor NR2F2 during hES cells differentiation. Microarray profiling showed that an alteration of about 1400 and 1900 transcripts occurred on D12 and D20 respectively compared to D0 whereas only 19 genes were altered between D12 and D20. This was found associated with corresponding expression pattern of chromatin remodelers, histone modifiers, miRNAs and lncRNAs marking the formation of progenitors and cardiomyocytes on D12 and D20 respectively. ChIP sequencing and sequential ChIP revealed the binding of NR2F2 with polycomb group member EZH2 and pluripotent factor OCT4 indicating its crucial involvement in cardiac differentiation. The study provides a detailed insight into genetic and epigenetic changes associated with hES cells differentiation into cardiac cells and a role for NR2F2 is deciphered for the first time to down-regulate OCT-4 via EZH2 during cardiac differentiation.
Genetically driven brain serotonin deficiency facilitates panic-like escape behavior in mice
Authors: Waider J , Popp S , Lange M D , Kern R , Kolter J F , Kobler J , Donner N C , Lowe K R , Malzbender J H , Brazell C J , Arnold M R , Aboagye B , Schmitt-Böhrer A , Lowry C A , Pape H C , Lesch K P
Published: October 2017

Multiple lines of evidence implicate brain serotonin (5-hydroxytryptamine; 5-HT) system dysfunction in the pathophysiology of stressor-related and anxiety disorders. Here we investigate the influence of constitutively deficient 5-HT synthesis on stressor-related anxiety-like behaviors using Tryptophan hydroxylase 2 (Tph2) mutant mice. Functional assessment of c-Fos after associated foot shock, electrophysiological recordings of GABAergic synaptic transmission, differential expression of the Slc6a4 gene in serotonergic neurons were combined with locomotor and anxiety-like measurements in different contextual settings. Our findings indicate that constitutive Tph2 inactivation and consequential lack of 5-HT synthesis in Tph2 null mutant mice (Tph2−/−) results in increased freezing to associated foot shock and a differential c-Fos activity pattern in the basolateral complex of the amygdala. This is accompanied by altered GABAergic transmission as observed by recordings of inhibitory postsynaptic currents on principal neurons in the basolateral nucleus, which may explain increased fear associated with hyperlocomotion and escape-like responses in aversive inescapable contexts. In contrast, lifelong 5-HT deficiency as observed in Tph2 heterozygous mice (Tph+/−) is able to be compensated through reduced GABAergic transmission in the basolateral nucleus of the amygdala based on Slc6a4 mRNA upregulation in subdivisions of dorsal raphe neurons. This results in increased activity of the basolateral nucleus of the amygdala due to associated foot shock. In conclusion, our results reflect characteristic syndromal dimensions of panic disorder and agoraphobia. Thus, constitutive lack of 5-HT synthesis influence the risk for anxiety- and stressor-related disorders including panic disorder and comorbid agoraphobia through the absence of GABAergic-dependent compensatory mechanisms in the basolateral nucleus of the amygdala.
Field-effect sensors – from pH sensing to biosensing: sensitivity enhancement using streptavidin–biotin as a model system
Authors: Lowe Benjamin M. , Sun Kai , Zeimpekis Ioannis , Skylaris Chris-Kriton , Green Nicolas G.
Published: October 2017

This critical review provides an overview of sensitivity-enhancement strategies and a systematic, quantitative analysis of field-effect transistor (IS-FET/BioFET) sensor literature.
Simultaneous detection of superoxide anion radicals and determination of the superoxide scavenging activity of antioxidants using a N,N-dimethyl-p-phenylene diamine/Nafion colorimetric sensor
Authors: Dondurmacıoğlu Ferda , Avan Aslı Neslihan , Apak Reşat
Published: October 2017

A novel colorimetric DMPD assay was developed for superoxide radicals generated by the NADH/PMS/O2system, and compared with conventional NBT assay.
A proton-hopping charge storage mechanism of ionic one-dimensional coordination polymers for high-performance supercapacitors
Authors: Phattharasupakun Nutthaphon , Wutthiprom Juthaporn , Kaenket Surasak , Maihom Thana , Limtrakul Jumras , Probst Michael , Nagarkar Sanjog S. , Horike Satoshi , Sawangphruk Montree
Published: October 2017

A proton-conducting coordination polymer of Zn2+ phosphate and protonated imidazole has been used as a novel supercapacitor material in aqueous electrolytes.
High-resolution microstrip NMR detectors for subnanoliter samples
Authors: Chen Ying , Mehta Hardeep S. , Butler Mark C. , Walter Eric D. , Reardon Patrick N. , Renslow Ryan S. , Mueller Karl T. , Washton Nancy M.
Published: October 2017

We present the numerical optimization and experimental characterization of two microstrip-based nuclear magnetic resonance (NMR) detectors.
Application of spin-ratio scaled MP2 for the prediction of intermolecular interactions in chemical systems
Authors: Tan Samuel Y. S. , Wylie Luke , Begic Ivan , Tran Dennis , Izgorodina Ekaterina I.
Published: October 2017

Accurate prediction of intermolecular interactions plays a pivotal role in many areas of chemistry and biology including (but not limited to) the design of pharmaceuticals, solid electrolytes and food additives.
A novel explanation for the enhanced colloidal stability of silver nanoparticles in the presence of an oppositely charged surfactant
Authors: Skoglund Sara , Blomberg Eva , Wallinder Inger Odnevall , Grillo Isabelle , Pedersen Jan Skov , Bergström L. Magnus
Published: October 2017

The structural behavior in aqueous mixtures of negatively charged silver nanoparticles (Ag NPs) together with the cationic surfactants cetyltrimethylammonium bromide (CTAB) and dodecyltrimethylammonium chloride (DTAC), respectively, has been investigated using SANS and SAXS.
A study of the competitive multiple hydrogen bonding effect and its associated excited-state proton transfer tautomerism
Authors: Chen Yi-Ting , Wu Pei-Jhen , Peng Chia-Yu , Shen Jiun-Yi , Tsai Cheng-Cheng , Hu Wei-Ping , Chou Pi-Tai
Published: October 2017

1,8-Dihydroxynaphthalene-2,7-dicarbaldehyde (DHDA) has been strategically designed and synthesized with the aim to study the competitive multiple hydrogen bonding (H-bonding) effect and the associated excited-state intramolecular proton transfer reaction (ESIPT).
Hybrid heterojunctions between a 2D transition metal dichalcogenide and metal phthalocyanines: their energy levels vis-à-vis current rectification
Authors: Banerjee Arnab , Kundu Biswajit , Pal Amlan J.
Published: October 2017

Hybrid heterojunctions between a monolayer of 2D transition metal dichalcogenides and another of metal-phthalocyanines have evidenced unidirectional electron-transfer.
The reaction of C5N−with acetylene as a possible intermediate step to produce large anions in Titan's ionosphere
Authors: Lindén Carl Fredrik , Žabka Ján , Polášek Miroslav , Zymak Illia , Geppert Wolf D.
Published: October 2017

Our experimental and theoretical study investigated possible reaction mechanisms producing large anions observed by the Cassini spacecraft in Titan's atmosphere.
Tuneable 3D printed bioreactors for transaminations under continuous-flow
Authors: Peris Edgar , Okafor Obinna , Kulcinskaja Evelina , Goodridge Ruth , Luis Santiago V. , Garcia-Verdugo Eduardo , O'Reilly Elaine , Sans Victor
Published: October 2017

A method to efficiently immobilize enzymes on 3D printed continuous-flow devices is presented.
A tuneable microfluidic system for long duration chemotaxis experiments in a 3D collagen matrix
Authors: Aizel Koceila , Clark Andrew G. , Simon Anthony , Geraldo Sara , Funfak Anette , Vargas Pablo , Bibette Jérôme , Vignjevic Danijela Matic , Bremond Nicolas
Published: October 2017

A microfluidic device to expose cells in 3D matrices to tuneable and stable chemokine gradients.
Enhanced surface acoustic wave cell sorting by 3D microfluidic-chip design
Authors: Ung W. L. , Mutafopulos K. , Spink P. , Rambach R. W. , Franke T. , Weitz D. A.
Published: October 2017

We demonstrate an acoustic wave driven microfluidic cell sorter that combines advantages of multilayer device fabrication with planar surface acoustic wave excitation.
Microfluidic magnetic bead conveyor belt
Authors: van Pelt Stijn , Frijns Arjan , den Toonder Jaap
Published: October 2017

Magnetic beads can be manipulated in a microfluidic channel using on-chip soft-magnetic structures and an external rotating field.
Synthesis of diastereomeric anhydrides of (RS)-ketorolac and (RS)-etodolac, semi-preparative HPLC enantioseparation, establishment of molecular asymmetry and recovery of pure enantiomers
Authors: Malik Poonam , Bhushan Ravi
Published: October 2017

Herein, enantioseparation of two anti-inflammatory drugs, namely, (RS)-ketorolac and (RS)-etodolac, commonly marketed and administered as racemates, was achieved by RP-HPLC.
An efficient route for design of luminescent composite materials based on polyethylene containing europium dibenzoylmethanate
Authors: Roitershtein Dmitrii M. , Puntus Lada N. , Lyssenko Konstantin A. , Taidakov Ilya V. , Varaksina Evgenia A. , Minyaev Mikhail E. , Gerasin Victor A. , Guseva Maria A. , Vinogradov Alexey A. , Savchenko Maria S. , Nifant'ev Ilya E.
Published: October 2017

A Eu-doped luminescent composite material based on polyethylene has been developed and studied by optical spectroscopy, luminescence intensity mapping, and SEM.
One step, high yield synthesis of amphiphilic carbon quantum dots derived from chia seeds: a solvatochromic study
Authors: Jones S. Solomon , Sahatiya Parikshit , Badhulika Sushmee
Published: October 2017

In this work, we demonstrate the high-yield synthesis of carbon quantum dots using a one-step eco-friendly, low-cost thermal treatment of a renewable biomass, i.e. natural chia seeds.
Self-ordering of nontrivial topological polarization structures in nanoporous ferroelectrics
Authors: Van Lich Le , Shimada Takahiro , Wang Jie , Kitamura Takayuki
Published: October 2017

Nontrivial topological polarization structures in nanoporous ferroelectrics.
Correction: Femtosecond laser ablation of transparent microphotonic devices and computer-generated holograms
Authors: Alqurashi Tawfiq , Montelongo Yunuen , Penchev Pavel , Yetisen Ali K. , Dimov Stefan , Butt Haider
Published: October 2017

Correction for ‘Femtosecond laser ablation of transparent microphotonic devices and computer-generated holograms’ by Tawfiq Alqurashi, et al., Nanoscale, 2017, 9, 13808–13819.
Photochromic RAFT reagent helps construct superior photoswitchable fluorescent polymer nanoparticles for rewritable fluorescence patterning and intracellular dual-color imaging
Authors: Chen Jian , Zhong Weibang , Xue Mingju , Wang Hong , Yu Maolin , Zhang Peisheng , Yi Pinggui
Published: October 2017

Photoswitchable fluorescent polymeric nanoparticles with photochromic RAFT chain transfer reagent were synthesized for rewritable fluorescence patterning and intracellular dual color imaging.
Detection of phosphate based on phosphorescence of Mn doped ZnS quantum dots combined with cerium(iii)
Authors: Qin Jin , Li Dongxia , Miao Yanming , Yan Guiqin
Published: October 2017

A simple and rapid room-temperature phosphorescence (RTP) sensor for phosphate detection was developed on the basis of Ce3+ modulated mercaptopropionic acid (MPA)-capped Mn-doped ZnS quantum dots (QDs).
Intercalating copper into layered TaS2 van der Waals gaps
Authors: Liu Rui , Wang Cong , Li Yuanyuan , Xie Yong , Chen Qiang , Chen Ziyu , Liu Qian
Published: October 2017

An efficient method to intercalate copper atoms into 2D layered 1T-TaS2 without disturbing the crystal structure of the target material.
A broad-band orange-yellow-emitting Lu2Mg2Al2Si2O12: Ce3+ phosphor for application in warm white light-emitting diodes
Authors: Zhou Yunan , Zhuang Weidong , Hu Yunsheng , Liu Ronghui , Jiang Zhouqing , Liu Yuanhong , Li Yanfeng , Zheng Yaling , Chen Lei , Zhong Jiyou
Published: October 2017

A newly developed orange-yellow-emitting Lu2Mg2Al2Si2O12: Ce3+ phosphor with excellent luminescent properties for warm white-LEDs.
Confined crystallization of a HKUST-1 metal–organic framework within mesostructured silica with enhanced structural resistance towards water
Authors: Mazaj M. , Čendak T. , Buscarino G. , Todaro M. , Zabukovec Logar N.
Published: October 2017

A HKUST-1 metal–organic framework was crystallized in the NH2-modified mesostructured silica FDU-12 in order to improve its structural stability upon water exposure.
Covalent organic frameworks as metal-free heterogeneous photocatalysts for organic transformations
Authors: Zhi Yongfeng , Li Ziping , Feng Xiao , Xia Hong , Zhang Yumin , Shi Zhan , Mu Ying , Liu Xiaoming
Published: October 2017

A robust two-dimensional covalent organic framework (COF-JLU5), which exhibits excellent heterogeneous photocatalytic performances for oxidative C–H functionalizations under visible-light irradiation using O2as a green oxygen source, is reported.
Relationships between luminescence properties and polyhedron distortion in Ca9−x−y−zMgxSryBazCe(PO4)7:Eu2+,Mn2+
Authors: Wang Chao , Wang Zhijun , Li Panlai , Cheng Jinge , Li Zhenling , Tian Miaomiao , Sun Yuansheng , Yang Zhiping
Published: October 2017

Bond length and symmetry of the ligand polyhedron have an important influence on the spectral band.
Flexible low-dimensional semiconductor field emission cathodes: fabrication, properties and applications
Authors: Chen Shanliang , Yang Weiyou
Published: October 2017

We present an overview on the fabrication, properties, and applications of flexible field emission cathodes based on low-dimensional semiconductor nanostructures.
Processing of syndecan-2 by matrix metalloproteinase-14 and effect of its cleavage on VEGF-induced tube formation of HUVECs
Authors: Lee Young Hun , Park Jun Hyoung , Cheon Dong Huey , Kim Taeyoung , Park Yae Eun , Oh Eok-Soo , Lee Ji Eun , Lee Seung-Taek
Published: October 2017

Syndecans (SDCs) are transmembrane proteoglycans that are involved in cell adhesion and cell communication. Specifically, SDC2 plays a key role in tumorigenesis, metastasis, and angiogenesis. Previously, we found that rat SDC2 is shed by matrix metalloproteinase-7 (MMP-7) in colon cancer cells. Here, we analyzed the susceptibility of rat SDC2 to various MMPs. We found that the rat SDC2 ectodomain (ECD) fused to the C-terminal Fc region, which was expressed in mammalian cells, was cleaved more efficiently by MMP-14 than MMP-7. Likewise, when anchored on the surface of HeLa cells, rat SDC2 was cleaved more efficiently by the treatment of MMP-14 than MMP-7 and was shed more readily by membrane-anchored MMP-14 than soluble MMP-14. Furthermore, MMP-14 cleaved recombinant SDC2-ECD expressed in Escherichia coli into multiple fragments. Using N-terminal amino acid sequencing and the top-down proteomics approach, we determined that the major cleavage sites were S88↓L89, T98↓M99, T100↓L101, D132↓P133, and N148↓L149 for rat SDC2-ECD and S55↓G56, S65↓P66, P75↓K76, N92↓I93 D122↓P123, and S138↓L139 for human SDC2-ECD. Finally, the rat and human SDC2-ECD lost the ability to suppress vascular endothelial growth factor-induced formation of capillary-like tubes by human umbilical vein endothelial cells following cleavage by MMP-14, but its major cleavage-site mutant of rat SDC2-ECD did not. These results suggest that MMP-14 is a novel enzyme responsible for degrading SDC2 and impairing its physiological roles including angiogenesis.
Extracellular microRNAs as messengers in the central and peripheral nervous system
Authors: Scott Hannah
Published: October 2017

MicroRNAs are small post-transcriptional regulators that play an important role in nervous system development, function and disease. More recently, microRNAs have been detected extracellularly and circulating in blood and other body fluids, where they are protected from degradation by encapsulation in vesicles, such as exosomes, or by association with proteins. These microRNAs are thought to be released from cells selectively through active processes and taken up by specific target cells within the same or in remote tissues where they are able to exert their repressive function. These characteristics make extracellular microRNAs ideal candidates for intercellular communication over short and long distances. This review aims to explore the potential mechanisms underlying microRNA communication within the nervous system and between the nervous system and other tissues. The suggested roles of extracellular microRNAs in the healthy and the diseased nervous system will be reviewed.
Pressurized Wideband Absorbance Findings in Healthy Neonates: A Preliminary Study
Authors: Wali Hamzah A. , Mazlan Rafidah , Kei Joseph
Published: October 2017

Purpose

The present study aimed to establish normative data for wideband absorbance (WBA) measured at tympanometric peak pressure (TPP) and 0 daPa and to assess the test–retest reliability of both measurements in healthy neonates.

Method

Participants of this cross-sectional study included 99 full-term neonates (165 ears) with mean chronological age of 46.7 hrs (
SD
= 26.3 hrs). Of the 99 neonates, 58 were Malay, 28 were Indian, and 13 were Chinese. The neonates who passed high-frequency (1 kHz) tympanometry, acoustic stapedial reflex, and distortion product otoacoustic emission screening tests were assessed using a pressurized WBA test (wideband tympanometry). To reduce the number of measurement points, the WBA responses were averaged to 16 one-third octave frequency bands from 0.25 to 8 kHz. A mixed-model analysis of variance was applied to the data to investigate the effects of frequency, ear, gender, and ethnicity on WBA. The analysis of variance was also used to compare between WBA measured at TPP and 0 daPa. An interclass correlation coefficient test was applied at each of the 16 frequency bands to measure the test–retest reliability of WBA at TPP and 0 daPa.

Results

Both WBA measurements at TPP and 0 daPa exhibited a multipeaked pattern with 2 maxima at 1.25–1.6 kHz and 6.3 kHz and 2 minima at 0.5 and 4 kHz. The mean WBA measured at TPP was significantly higher than that measured at 0 daPa at 0.25, 0.4, 0.5, 1.25, and 1.6 kHz only. A normative data set was developed for absorbance at TPP and at 0 daPa. There was no significant effect of ethnicity, gender, and ear on both measurements of WBA. The test–retest reliability of WBA at TPP and 0 daPa was high with the interclass correlation coefficient ranging from 0.77 to 0.97 across the frequencies.

Conclusions

Normative data of WBA measured at TPP and 0 daPa for neonates were provided in the present study. Although WBA at TPP was slightly higher than the WBA measured at 0 daPa at some frequencies below 2 kHz, the WBA patterns of the 2 measurements were nearly identical. Moreover, the test–retest reliability of both WBA measurements was high.
Ordinary Interactions Challenge Proposals That Maternal Verbal Responses Shape Infant Vocal Development
Authors: Fagan Mary K. , Doveikis Kate N.
Published: October 2017

Purpose

This study tested proposals that maternal verbal responses shape infant vocal development, proposals based in part on evidence that infants modified their vocalizations to match mothers' experimentally manipulated vowel or consonant–vowel responses to most (i.e., 70%–80%) infant vocalizations. We tested the proposal in ordinary rather than experimentally manipulated interactions.

Method

Response-based proposals were tested in a cross-sectional study of 35 infants, ages 4 to 14 months, engaged in everyday interactions in their homes with their mothers using a standard set of toys and picture books.

Results

Mothers responded to 30% of infant vocalizations with vocal behaviors of their own, far fewer than experimentally manipulated response rates. Moreover, mothers produced comparatively few vowel and consonant–vowel models and responded to infants' vowel and consonant–vowel vocalizations in similar numbers. Infants showed little evidence of systematically modifying their vocal forms to match maternal responses in these interactions. Instead, consonant–vowel vocalizations increased significantly with infant age.

Conclusions

Results obtained in ordinary interactions, rather than response manipulation, did not provide substantial support for response-based mechanisms of infant vocal development. Consistent with other research, however, consonant–vowel productions increased with infant age.
Architecture of the Suprahyoid Muscles: A Volumetric Musculoaponeurotic Analysis
Authors: Shaw Stephanie M. , Martino Rosemary , Mahdi Ali , Sawyer Forrest Kip , Mathur Sunita , Hope Andrew , Agur Anne M.
Published: October 2017

Purpose

Suprahyoid muscles play a critical role in swallowing. The arrangement of the fiber bundles and aponeuroses has not been investigated volumetrically, even though muscle architecture is an important determinant of function. Thus, the purpose was to digitize, model in three dimensions, and quantify the architectural parameters of the suprahyoid muscles to determine and compare their relative functional capabilities.

Method

Fiber bundles and aponeuroses from 11 formalin-embalmed specimens were serially dissected and digitized in situ. Data were reconstructed in three dimensions using Autodesk Maya. Architectural parameters were quantified, and data were compared using independent samplest-tests and analyses of variance.

Results

Based on architecture and attachment sites, suprahyoid muscles were divided into 3 groups: anteromedial, superolateral, and superoposterior. Architectural parameters differed significantly (p< .05) across muscles and across the 3 groups, suggesting differential roles in hyoid movement during swallowing. When activated simultaneously, anteromedial and superoposterior muscle groups could work together to elevate the hyoid.

Conclusions

The results suggest that the suprahyoid muscles can have individualized roles in hyoid excursion during swallowing. Muscle balance may be important for identifying and treating hyolaryngeal dysfunction in patients with dysphagia.
Using Self-Regulated Strategy Development to Support Curriculum-Based Homework: A Case Study
Authors: Dunn Davison Megan
Published: October 2017

There are multiple aspects of language to consider when treating language and literacy impairments in school-age children. Therefore, it is important for speech-language pathologists (SLPs) to understand how to systematically and comprehensively target language in intervention while also considering home and school expectations. The purpose of this paper is to explore a case involving a third grade student struggling with writing and the use of a cognitive apprenticeship model of writing to promote multiple aspects of language using curriculum-based materials and parent support.
Telehealth for Dysphagia Rehabilitation: The Present and the Future
Authors: Malandraki Georgia A. , Kantarcigil Cagla
Published: October 2017

Dysphagia affects about nine million adults and half a million children annually in the United States alone, and its prevalence is only projected to increase as the baby boomer generation grows older. For many individuals who live in rural or underserved areas, accessing a speech-language pathologist (SLP) with expertise in dysphagia can be challenging. Telehealth appears to be a viable solution to address the needs of individuals living in these areas, and for patients and clinicians with mobility/access limitations. This article provides an overview of the current research evidence in dysphagia telehealth and identifies research and clinical practice gaps as well as potential solutions. Our aim is to provide foundational knowledge for dysphagia clinicians who are interested in entering the telehealth arena.
Discrete‐level memristive circuits for HTM‐based spatiotemporal data classification system
Authors: Irmanova Aidana , Ibrayev Timur , James Alex Pappachen
Published: October 2017

The authors propose a discrete‐level memristive memory design for analogue data processing in hardware implementations of hierarchical temporal memory (HTM). In this study, memristors were set to ternary and quaternary states in a sub‐cell by application of different write voltage levels through a resistive network configuration. Simulations of the proposed circuit show that the highest number of discrete output levels of the memory was achieved using quaternary logic. However overall, using the same number of sub‐cells and ternary logic exhibits the lowest relative error rate. For data classification purposes, the proposed discrete‐level memristive cells are incorporated into the TM of HTM architecture, and its hardware circuit is presented for pattern recognition. They report improved results of face recognition using AR, ORL and UFI databases, and TIMIT database for speech recognition. These results are compared with the earlier design of HTM having only the spatial pooler (SP). Accuracy of the HTM architecture incorporating both SP and TM with discrete‐level memristive cells for face recognition increased from 76.5 to 83.5% for AR database and speech recognition accuracy is improved from 73.3 to 93.3%.
Passive islanding detection scheme based on autocorrelation function of modal current envelope for photovoltaic units
Authors: Haider Raza , Kim Chul Hwan , Ghanbari Teymoor , Bukhari Syed Basit Ali , Saeed uz Zaman Muhammad , Baloch Shazia , Oh Yun Sik
Published: October 2017

Islanding detection in power systems poses a challenge that can result in technical problems and safety hazards. This study examines a new passive islanding detection method for photovoltaic‐based distributed generation (DG) units. The modal signal of the three‐phase current and its envelope are calculated for a targeted DG unit. Variance in the autocorrelation of the modal current envelope (VAMCE) is used as an islanding detection criterion in the proposed method. The proposed method employs autocorrelation function (ACF) of modal current envelope (derived by Hilbert‐transform‐based approach) to extract the transient content. Then, the variance of the ACF is calculated, called criterion VAMCE to distinguish between islanded and normal operating conditions. The main advantage of the proposed technique is more relevant to its more accuracy and smaller non‐detection zone in comparison with the other similar passive techniques. Since the VAMCE has significant variation during islanding conditions and negligible change in normal conditions, it can be used for detection of islanding condition effectively. The method was evaluated through several simulations under different islanded and normal operating conditions. The results confirm that the proposed method has better accuracy and speed compared to other similar methods.
Photonics‐assisted wireless link based on mm‐wave reconfigurable antennas
Authors: Feliciano daCosta Igor , Cerqueira Sodré Arismar , Rodriguez Páez Juan Sebastián , Puerta Rafael , Vegas Olmos Juan José , da Silva Luis Gustavo , Spadoti Danilo Henrique , Tafur Monroy Idelfonso
Published: October 2017

The authors report a novel concept for photonics‐assisted and broadband optical‐wireless indoor networks based on optically‐controlled reconfigurable antenna arrays (OCRAAs) and photonic down conversion (PDC) techniques, operating in the 28 and 38 GHz frequency bands. The antenna bandwidth is optically reconfigured by using photoconductive switches. In this way, the optical backhaul can either be used for high data rate transmission and remotely controlling the antenna operation. Experimental results on 40 Mbaud with complex modulation formats up to 64‐QAM wireless transmission supported by PDC are successfully reported under 78 dB link budget requirement. Two OCRAAs have been simultaneously tested in an indoor environment at 1.25 Gb/s wireless data signal transmission. The proposed antenna design significantly increases the degrees of freedom, opening new possibilities in the development of antennas for access networks in the mm‐wave frequency range.
A new paguroid from the type Maastrichtian (upper Cretaceous, the Netherlands) and erection of a new family
Authors: Fraaije René H.B. , Van Bakel Barry W.M. , Jagt John W.M.
Published: October 2017

On the basis of a fragmentary carapace a new extinct paguroid, Annuntidiogenes massetispinosus n. sp., is described from the upper Meerssen Member (Maastricht Formation, upper Maastrichtian) of the Maastrichtian type area in the southeast Netherlands. The new taxon represents the fifth and stratigraphically youngest member of this Mesozoic genus that shows a remarkably close resemblance to the extant diogenids Aeropaguristes Rahayu and McLaughlin, 2010 (Rahayu DL, McLaughlin PA. 2010. Areopaguristes, a generic replacement name for Stratiotes Thomson, 1899 (Crustacea: Decapoda: Paguroidea: Diogenidae). Zootaxa 2509: 67–68), Paguristes Dana, 1851 (Dana JD. 1851. Conspectus crustaceorum quae in orbis terrarum circumnavigatione, Carolo Wilkes e classe reipublicae foederatae duce, lexit et descripsit. (Preprint from) Proceedings of the Academy of Natural Sciences, Philadelphia 5: 267–272) and Pseudopaguristes McLaughlin, 2002 (McLaughlin PA. 2002. Pseudopaguristes, a new and aberrant genus of hermit crabs (Anomura: Paguridea: Diogenidae). Micronesica 34(2): 185–199). Morphological features of paguroid carapaces, not previously used by neontologists, form the basis for a further systematic refinement of the Paguroidea, with the erection of a new family, the Calcinidae n. fam.
Spectral methods for Langevin dynamics and associated error estimates
Authors: Roussel Julien , Stoltz Gabriel
Published: October 2017

We prove the consistency of Galerkin methods to solve Poisson equations where the differential operator under consideration is hypocoercive. We show in particular how the hypocoercive nature of the generator associated with Langevin dynamics can be used at the discrete level to first prove the invertibility of the rigidity matrix, and next provide error bounds on the approximation of the solution of the Poisson equation. We present general convergence results in an abstract setting, as well as explicit convergence rates for a simple example discretized using a tensor basis. Our theoretical findings are illustrated by numerical simulations.
New advances in the laboratory characterization of refractories: testing and modelling
Authors: Poirier Jacques , Blond Eric , de Bilbao Emmanuel , Michel Rudy , Coulon Antoine , Gillibert Jean , Boussuge Michel , Zhang Yang , Ryckelynk David , Dusserre Gilles , Cutard Thierry , Leplay Paul
Published: October 2017

This publication presents new advances in the field of refractories characterization. These laboratory methods that combine experiments and numerical analyses and concern both the thermomechanical and thermochemical behaviour are illustrated through different examples: identification of asymmetrical creep, determination of elastic and inelastic properties, measurements of macroscopic deformation, phase transformations or corrosion kinetics. These advanced techniques offer the refractory community new opportunities to improve the knowledge and the prediction of the phenomena of degradation of the refractories.
A fuzzy imperfect production and repair inventory model with time dependent demand, production and repair rates under inflationary conditions
Authors: Jain Shalini , Tiwari Sunil , Cárdenas-Barrón Leopoldo Eduardo , Shaikh Ali Akbar , Singh Shiv Raj
Published: October 2017

This research work derives an integrated inventory model for imperfect production/remanufacturing process with time varying demand, production and repair rates under inflationary environment. This inventory model deals with the joint manufacturing and remanufacturing options. There is a collection process devoted to collect used items with the aim to remanufacture them. Both production and repair runs generate imperfect items. The repair process remanufactures used and imperfect items. Further, it is also considered that the remanufactured item that is classified as good has exactly same quality as that of new one. Demand rate is supposed as time dependent. The production rate is assumed to be demand dependent and therefore it is also time dependent. The repair rate is supposed to be a function of time. All system costs are contemplated in uncertain environment. Therefore, the costs are considered as fuzzy nature. Theoretical results are illustrated thru a numerical example. Finally, a sensitivity analysis is performed in order to know the impact of different parameters on the optimal policy.
Bicriteria scheduling for due date assignment with total weighted tardiness
Authors: Lin Hao , He Cheng , Lin Yixun
Published: October 2017

In the due date assignment, the bicriteria scheduling models are motivated by the trade-off between the due date assignment cost and a performance criterion of the scheduling system. The bicriteria scheduling models related to the maximum tardiness and the weighted number of tardy jobs have been studied in the literature. In this paper we consider a new model with criteria of the due date assignment cost and the total weighted tardiness. The main results are polynomial-time algorithms for the linear combination version, the constraint version, and the Pareto optimization version of bicriteria scheduling.
Limb and Flap Salvage in Gustilo IIIC Injuries Treated by Vascular Repair and Emergency Free Flap Transfer
Authors: Papa Giovanni , Ramella Vittorio , Novati Federico , Ahcan Uros , Stocco Chiara , Arnež Zoran
Published: October 2017

Background Gustilo classification system defines IIIC fractures as open fractures associated with an arterial injury that requires repair. The aim of our study was to analyze the early outcome in terms of limb and flap salvage, early amputation, and early complication rate in patients with Gustilo IIIC open fractures treated in an emergency setup.

Methods We retrospectively reviewed 20 patients with Gustilo IIIC injuries treated by the “fix and flap” principle during the first surgical procedure in the first 24 hours after injury (emergency free flap transfer). All patients underwent surgery with radical debridement, wound irrigation, skeletal stabilization, vascular repair, and immediate free flap coverage.

Results In this study, 18 patients were men (90%) and 2 were women (10%). In all patients, a vascular repair was performed and in 17 cases (85%), the lower limb/foot was avascular and limb salvage was performed. Three patients had one vessels injured (15%) and 17 had two or three vessels injured (85%). In 9 out of 20 (45%), a revision surgery was needed for arterial (10%, 2 patients), arterial–venous (15%, 3 patients), and venous thrombosis (20%, 4 patients), while 4 patients required an early amputation (20%) and 1, a late one (5%). In three patients (15%), a flap loss occurred. Superficial infection occurred in seven cases (35%) and deep infection (osteomyelitis) in one (5%).

Conclusion A single-stage procedure performed in an emergency operating room could lead to an effective outcome with a high rate of limb salvage and satisfying long-term results.
Meerschweinchen stressarm behandeln und Unwohlsein erkennen
Authors: Schneider Barbara
Published: October 2017

Meerschweinchen sind sehr stressanfällig. Stress äußert sich bei diesen Tieren jedoch,
ähnlich wie Schmerzen, oft nur subtil. Daher muss der behandelnde Tierarzt die Tiere
aufmerksam beobachten. Zudem kann er mit wenigen, simplen Maßnahmen dafür sorgen, den
Stress der Behandlung zu reduzieren.
Narkosemanagement beim Vogel
Authors: Bücking Bianca , Wüst Elisa
Published: October 2017

In den letzten Jahren hat die Haltung von Exoten in privaten Haushalten deutlich zugenommen. Die Tiere
sind hierbei häufig Familienmitglieder. Aus diesem Grund steigt die Nachfrage nach aufwendigeren
Behandlungen stetig. Allerdings müssen die besonderen Ansprüche des Vogels als Patient berücksichtigt
werden.
Eine zeitgemäße Weiterbildung
Authors: Gostomzyk Johannes , Nüchtern Elisabeth , von Mittelstaedt Gert
Published: October 2017

Die Novellierung der Weiterbildungsordnung (WBO) für Ärzte zu einer kompetenzbasierten Muster-Weiterbildungsordnung (M-WBO) steht an. Auf der Jahrestagung der Deutschen Gesellschaft für Sozialmedizin und Prävention 2016 in Essen wurde in einem Workshop des Fachbereichs 2 der DGSMP „Praktische Sozialmedizin und Rehabilitation“ über die strukturelle und inhaltliche Weiterentwicklung der WBO zur Zusatzbezeichnung Sozialmedizin diskutiert.
Men’s Involvement in a Parenting Programme to Reduce Child Maltreatment and Gender-Based Violence: Formative Evaluation in Uganda
Authors: Siu Godfrey E. , Wight Daniel , Seeley Janet , Namutebi Carolyn , Sekiwunga Richard , Zalwango Flavia , Kasule Sarah
Published: October 2017

Parenting programmes involving fathers can reduce child maltreatment and gender-based violence. However, most parenting programmes find it difficult to recruit fathers. We piloted a 21 session parenting intervention, ‘Parenting for Respectability’, with fathers and mothers near Kampala, Uganda. Sixty-one fathers and 83 mothers were recruited initially and 52 fathers and 76 mothers retained to the end. We interviewed with 24 fathers and 16 mothers. Data were analysed thematically. Success in involving fathers was probably due to (a) the first 10 sessions being father-only, allowing them to share experiences before participating in mixed-sex sessions; (b) exploiting men’s pre-existing motivation to improve their children’s behaviour, thereby enhancing family respectability; and (c) the interactive, participatory delivery. Mixed sessions enabled couples to clarify conflicting perspectives regarding spousal relationships and gendered norms. However, men experienced social pressure to conform to conventional masculinity, suggesting the need to instil intervention values at community level.
Observability and synchronization of neuron models
Authors: Aguirre Luis A. , Portes Leonardo L. , Letellier Christophe
Published: October 2017

Observability is the property that enables recovering the state of a dynamical system from a reduced number of measured variables. In high-dimensional systems, it is therefore important to make sure that the variable recorded to perform the analysis conveys good observability of the system dynamics. The observability of a network of neuron models depends nontrivially on the observability of the node dynamics and on the topology of the network. The aim of this paper is twofold. First, to perform a study of observability using four well-known neuron models by computing three different observability coefficients. This not only clarifies observability properties of the models but also shows the limitations of applicability of each type of coefficients in the context of such models. Second, to study the emergence of phase synchronization in networks composed of neuron models. This is done performing multivariate singular spectrum analysis which, to the best of the authors' knowledge, has not been used in the context of networks of neuron models. It is shown that it is possible to detect phase synchronization: (i) without having to measure all the state variables, but only one (that provides greatest observability) from each node and (ii) without having to estimate the phase.
Optimization of the defects and the nonradiative lifetime of GaAs/AlGaAs double heterostructures
Authors: Cevher Z. , Folkes P. A. , Hier H. S. , VanMil B. L. , Connelly B. C. , Beck W. A. , Ren Y. H.
Published: October 2017

We used Raman scattering and time-resolved photoluminescence spectroscopy to investigate the molecular-beam-epitaxy (MBE) growth parameters that optimize the structural defects and therefore the internal radiative quantum efficiency of MBE-grown GaAs/AlGaAs double heterostructures (DH). The DH structures were grown at two different temperatures and three different As/Ga flux ratios to determine the conditions for an optimized structure with the longest nonradiative minority carrier lifetime. Raman scattering measurements show an improvement in the lattice disorder in the AlGaAs and GaAs layers as the As/Ga flux ratio is reduced from 40 to 15 and as the growth temperature is increased from 550 to 595 °C. The optimized structure is obtained with the As/Ga flux ratio equal to 15 and the substrate temperature 595 °C. This is consistent with the fact that the optimized structure has the longest minority carrier lifetime. Moreover, our Raman studies reveal that incorporation of a distributed Bragg reflector layer between the substrate and DH structures significantly reduces the defect density in the subsequent epitaxial layers.
Electrical characteristics and density of states of thin-film transistors based on sol-gel derived ZnO channel layers with different annealing temperatures
Authors: Wang S. , Mirkhani V. , Yapabandara K. , Cheng R. , Hernandez G. , Khanal M. P. , Sultan M. S. , Uprety S. , Shen L. , Zou S. , Xu P. , Ellis C. D. , Sellers J. A. , Hamilton M. C. , Niu G. , Sk M. H. , Park M.
Published: October 2017

We report on the fabrication and electrical characterization of bottom gate thin-film transistors (TFTs) based on a sol-gel derived ZnO channel layer. The effect of annealing of ZnO active channel layers on the electrical characteristics of the ZnO TFTs was systematically investigated. Photoluminescence (PL) spectra indicate that the crystal quality of the ZnO improves with increasing annealing temperature. Both the device turn-on voltage (Von) and threshold voltage (VT) shift to a positive voltage with increasing annealing temperature. As the annealing temperature is increased, both the subthreshold slope and the interfacial defect density (Dit) decrease. The field effect mobility (μFET) increases with annealing temperature, peaking at 800 °C and decreases upon further temperature increase. An improvement in transfer and output characteristics was observed with increasing annealing temperature. However, when the annealing temperature reaches 900 °C, the TFTs demonstrate a large degradation in both transfer and output characteristics, which is possibly produced by non-continuous coverage of the film. By using the temperature-dependent field effect measurements, the localized sub-gap density of states (DOSs) for ZnO TFTs with different annealing temperatures were determined. The DOSs for the subthreshold regime decrease with increasing annealing temperature from 600 °C to 800 °C and no substantial change was observed with further temperature increase to 900 °C.
A large-diameter hollow-shaft cryogenic motor based on a superconducting magnetic bearing for millimeter-wave polarimetry
Authors: Johnson B. R. , Columbro F. , Araujo D. , Limon M. , Smiley B. , Jones G. , Reichborn-Kjennerud B. , Miller A. , Gupta S.
Published: October 2017

In this paper, we present the design and measured performance of a novel cryogenic motor based on a superconducting magnetic bearing (SMB). The motor is tailored for use in millimeter-wave half-wave plate (HWP) polarimeters, where a HWP is rapidly rotated in front of a polarization analyzer or polarization-sensitive detector. This polarimetry technique is commonly used in cosmic microwave background polarization studies. The SMB we use is composed of fourteen yttrium barium copper oxide (YBCO) disks and a contiguous neodymium iron boron (NdFeB) ring magnet. The motor is a hollow-shaft motor because the HWP is ultimately installed in the rotor. The motor presented here has a 100 mm diameter rotor aperture. However, the design can be scaled up to rotor aperture diameters of approximately 500 mm. Our motor system is composed of four primary subsystems: (i) the rotor assembly, which includes the NdFeB ring magnet, (ii) the stator assembly, which includes the YBCO disks, (iii) an incremental encoder, and (iv) the drive electronics. While the YBCO is cooling through its superconducting transition, the rotor is held above the stator by a novel hold and release mechanism. The encoder subsystem consists of a custom-built encoder disk read out by two fiber optic readout sensors. For the demonstration described in this paper, we ran the motor at 50 K and tested rotation frequencies up to approximately 10 Hz. The feedback system was able to stabilize the rotation speed to approximately 0.4%, and the measured rotor orientation angle uncertainty is less than 0.15°. Lower temperature operation will require additional development activities, which we will discuss.
Rate of hemifusion diaphragm dissipation and ability to form three-junction bound HD determined by lipid composition
Authors: Gardner Jasmine M. , Abrams Cameron F.
Published: October 2017

Though the hemifusion diaphragm (HD) is widely accepted as an intermediate in bilayer membrane fusion, lipid contributions toward HD stability and dynamics are still not fully understood. In this paper, we study large, binary, protein-free HD systems at varying compositions of negative intrinsic curvature (NIC) lipids using molecular dynamics (MD) simulations of a solvent-free coarse-grained lipid model. Under MD, initially created HDs are found to relax to three major end states depending on the composition and lipid intrinsic curvature. Low compositions of NIC lipids or weak intrinsic curvature result in double-bilayer end states, and moderate compositions of moderate to strong NIC lipids result in metastable fusion pores. Importantly, high compositions of moderate NIC lipids result in a metastable HD that persists beyond μs time scales. NIC lipids stabilize the HD by filling the junction core around the HD. Sorting of NIC lipids toward the three-junction region occurs in fused-endpoint systems, but no significant sorting was seen in systems that end in a double bilayer indicating that high line tension at the triple junction drives HD dissipation faster than sorting can enrich that junction enough to lower that line tension. The appearance of three end states dependent on the NIC lipid composition highlights the necessity of NIC lipids for non-leaky fusion.
Design and test of a simple fast electromagnetic inductive gas valve for planar pulsed inductive plasma thruster
Authors: Guo Dawei , Cheng Mousen , Li Xiaokang
Published: October 2017

In support of our planar pulsed inductive plasma thruster research, a fast electromagnetic inductive valve for a gas propellant injection system has been built and tested. A new and important design feature is the use of a conical diaphragm as the action part, which greatly contributes to the virtue of simplicity for adopting the resultant force of the diaphragm deformation as the closing force. An optical transmission technique is adopted to measure the opening and closing characters of the valve while the gas throughput is determined by measuring the pressure change per pulse in a test chamber with a capacitance manometer. The experimental results revealed that the delay time before the valve reaction is less than 40 μs, and the valve pulse width is no longer than 160 μs full width at half maximum. The valve delivers 0-2.5 mg of argon gas per pulse varied by adjusting the drive voltage and gas pressure.