bluuebunny/crossref_metadata_2025 huggingface dataset:
From Exclusion to Inhabitation: Response to Gray, Benjamin. Citizenship as Barrier and Opportunity for Ancient Greek and Modern Refugees. Humanities, 2018, 7, 72
Authors: Boano Camillo
Published: July 2019

Spaces of refuge represent the paradoxical encounters between a series of governmental forces, disciplinary knowledge, aesthetic regimes and spatial conditions that tend to arrest, fix in time and space forms of lives. Considering the fact that camps are meant to be the materialisation of a temporal status, spatial and political, the proposition posed by Benjamin Gray’s Citizenship as Barrier and Opportunity for Ancient Greek and Modern Refugees, to look at “citizenship-in-exile” practices in ancient Greece and their forms of “improvised quasi-civic communities”, is welcome as it is refreshing. This short response engages with Gray’s text, addressing two different but interconnected points: in one respect, I hope to rescue Agamben’s work from its linear reading by commenting on the depoliticization of the camp and the critique of its exceptionalism; and, in another, I wish to provoke reflection around the universalising claim of hospitality and full assimilation, by introducing the disruptive terminology of inhabitation. This critical insertion aims to redefine an ethical relationship with the space, as a space of and for life, that Agamben sees as the basis for a new ethics, reversing its status as a productive and active force where the camp, in its paradigmatic reading, and the form of life it generates, helps to think beside the exceptional and move to inhabit such indistinctions.
Long-Term Care Admissions Following Hospitalization: The Role of Social Vulnerability
Authors: Godin Judith , Theou Olga , Black Karen , McNeil Shelly A. , Andrew Melissa K.
Published: July 2019

We sought to understand the association between social vulnerability and the odds of long-term care (LTC) placement within 30 days of discharge following admission to an acute care facility and whether this association varied based on age, sex, or pre-admission frailty. Patients admitted to hospital with acute respiratory illness were enrolled in the Canadian Immunization Research Network’s Serious Outcomes Surveillance Network during the 2011/2012 influenza season. Participants (N = 475) were 65 years or older (mean = 78.6, SD = 7.9) and over half were women (58.9%). Incident LTC placement was rare (N = 15); therefore, we used penalized likelihood logistic regression analysis. Social vulnerability and frailty indices were built using a deficit accumulation approach. Social vulnerability interacted with frailty and age, but not sex. At age 70, higher social vulnerability was associated with lower odds of LTC placement at high levels of frailty (frailty index (FI) = 0.35; odds ratio (OR) = 0.32, 95% confidence interval (CI) = 0.09–0.94), but not at lower levels of frailty. At age 90, higher social vulnerability was associated with greater odds of LTC placement at lower levels of frailty (FI = 0.05; OR = 14.64, 95%CI = 1.55, 127.21 and FI = 0.15; OR = 7.26, 95%CI = 1.06, 41.84), but not at higher levels of frailty. Various sensitivity analyses yielded similar results. Although younger, frailer participants may need LTC, they may not have anyone advocating for them. In older, healthier patients, social vulnerability was associated with increased odds of LTC placement, but there was no difference among those who were frailer, suggesting that at a certain age and frailty level, LTC placement is difficult to avoid even within supportive social situations.
Male-Specific Long Noncoding RNA TTTY15 Inhibits Non-Small Cell Lung Cancer Proliferation and Metastasis via TBX4
Authors: Lai I-Lu , Chang Ya-Sian , Chan Wen-Ling , Lee Ya-Ting , Yen Ju-Chen , Yang Chin-An , Hung Shih-Ya , Chang Jan-Gowth
Published: July 2019

Gender affects cancer susceptibility. Currently, there are only a few studies on Y chromosome-linked long noncoding RNAs (lncRNAs), and the potential association between lncRNAs and cancers in males has not been fully elucidated. Here, we examined the expression of testis-specific transcript Y-linked 15 (TTTY15) in 37 males with non-small cell lung cancer (NSCLC), and performed circular chromosome conformation capture with next-generation sequencing to determine the genomic interaction regions of the TTTY15 gene. Our results showed that the expression levels of TTTY15 were lower in NSCLC tissues. Lower TTTY15 expression levels were associated with Tumor-Node-Metastasis (TNM) stage. A TTTY15 knockdown promoted malignant transformation of NSCLC cells. Based on the bioinformatics analysis of circular chromosome conformation capture data, we found that T-box transcription factor 4 (TBX4) may be a potential target gene of TTTY15. The RNA immunoprecipitation and chromatin immunoprecipitation results showed that TTTY15 may interact with DNA (cytosine-5)-methyltransferase 3A (DNMT3A), and the TTTY15 knockdown increased the binding of DNMT3A to the TBX4 promoter. We concluded that low TTTY15 expression correlates with worse prognosis among patients with NSCLC. TTTY15 promotes TBX4 expression via DNMT3A-mediated regulation. The identification of lncRNAs encoded by male-specific genes may help to identify potential targets for NSCLC therapy.
Using Flexible Blades to Improve the Performance of Novel Small-Scale Counter-Rotating Self-Adaptable Wave Energy Converter for Unmanned Marine Equipment
Authors: Sun Chongfei , Shang Jianzhong , Luo Zirong , Lu Zhongyue , Wu Guoheng , Zhu Yiming
Published: July 2019

Unmanned marine equipment has been increasingly developed for open seas. The lack of efficient and reliable power supply is currently one of the bottlenecks restricting the practical application of these devices. In order to provide a viable power supply method for unmanned marine equipment, such as sonic buoys and sea robots, we originally propose a novel small-scale flexible blade wave energy converter (WEC) based on self-adaptable counter-rotating operation mechanism. The flexible blade WEC is designed on the basis of the rigid blade WEC with the caging device. This paper identifies the key factors affecting WEC performance through theoretical analysis. According to the numerical simulation analysis, the output mechanical power of the double-layer absorber is 12.8 W, and the hydraulic efficiency is 36.3%. The results of the verification experiment show that the peak power of WEC is 5.8 W and the average power is 3.2 W. The WEC with 65Mn flexible blade under most experimental conditions has the best performance when the blade thickness is 0.10 mm. The study shows that the new generation WEC can effectively overcome the excessive fluctuation of the output power of the previous generation WEC. The output power curve of the novel WEC is relatively smooth, which is conducive to its smooth operation and subsequent utilization and storage of electrical energy.
Modeling and Efficiency Optimization of Steam Boilers by Employing Neural Networks and Response-Surface Method (RSM)
Authors: Maddah Heydar , Sadeghzadeh Milad , Ahmadi Mohammad Hossein , Kumar Ravinder , Shamshirband Shahaboddin
Published: July 2019

Boiler efficiency is called to some extent of total thermal energy which can be recovered from the fuel. Boiler efficiency losses are due to four major factors: Dry gas flux, the latent heat of steam in the flue gas, the combustion loss or the loss of unburned fuel, and radiation and convection losses. In this research, the thermal behavior of boilers in gas refinery facilities is studied and their efficiency and their losses are calculated. The main part of this research is comprised of analyzing the effect of various parameters on efficiency such as excess air, fuel moisture, air humidity, fuel and air temperature, the temperature of combustion gases, and thermal value of the fuel. Based on the obtained results, it is possible to analyze and make recommendations for optimizing boilers in the gas refinery complex using response-surface method (RSM).
Association between the No-Reflow Phenomenon and Soluble CD40 Ligand Level in Patients with Acute ST-Segment Elevation Myocardial Infarction
Authors: Tascanov Mustafa Begenc , Tanriverdi Zulkif , Gungoren Fatih , Besli Feyzullah , Erkus Muslihittin Emre , Gonel Ataman , Koyuncu Ismail , Demirbag Recep
Published: July 2019

Background and objectives: No-reflow (NR) phenomenon is defined as insufficient myocardial perfusion in coronary circulation in the absence of angiographic evidence of mechanical obstruction. The primary mechanisms of the NR occurrence are thought to be high platelet activity and thrombus burden. Soluble CD40 ligand (sCD40L), which is released into the plasma following platelet activation, accelerates the inflammatory process and causes further platelet activation. The aim of our study is to investigate the relationship between the NR phenomenon and sCD40L level in patients with ST-elevation myocardial infarction (STEMI). Methods: A total of 81 acute STEMI patients undergoing primary percutaneous coronary intervention and 40 healthy participants were included in this study. Acute STEMI patients were classified into two groups: 41 patients with the NR phenomenon (NR group) and 40 patients without the NR phenomenon (non-NR group). The serum sCD40L level was measured for all groups. Results: The serum sCD40L level was significantly higher in the NR group than in non-NR and control groups (379 ± 20 pg/mL, 200 ± 15 pg/mL and 108 ± 6.53 pg/mL, respectively; p < 0.001). Univariate regression analysis demonstrated that male sex, age, Gensini score and sCD40L level were the possible factors affecting the occurrence of the NR phenomenon. In multivariate regression analysis, age (odds ratio [OR], 1.091; 95% confidence interval [CI], 1.023–1.163; p < 0.008) and serum sCD40L (OR, 1.016; 95% CI, 1.008–1.024; p < 0.001) remained the independent predictor of the presence of NR. Conclusions: Our study showed that serum sCD40L level was an independent predictor of the NR phenomenon occurrence.
Origin and Sources of Minerals and Their Impact on the Hydrocarbon Reservoir Quality of the PaleogeneLulehe Formation in the Eboliang Area, Northern Qaidam Basin, China
Authors: Chen Bo , Wang Feng , Shi Jian , Chen Fenjun , Shi Haixin
Published: July 2019

The Lulehe sandstone in the Eboliang area is a major target for hydrocarbon exploration in the northern Qaidam Basin. Based on an integrated analysis including thin section analysis, scanning electron microscopy, X-ray diffraction, cathodoluminescence investigation, backscattered electron images, carbon and oxygen stable isotope analysis and fluid inclusion analysis, the diagenetic processes mainly include compaction, cementation by carbonate and quartz, formation of authigenic clay minerals (i.e., chlorite, kaolinite, illite-smectite and illite) and dissolution of unstable materials. Compaction is the main factor for the deterioration of reservoir quality; in addition, calcite cement and clay minerals are present, including kaolinite, pore-filling chlorite, illite-smectite and illite, which also account for reservoir quality reduction. Integration of petrographic studies and isotope geochemistry reveals the carbonate cements might have originated from mixed sources of bioclast- and organic-derived CO2 during burial. The quartz cement probably formed by feldspar dissolution, illitization of smectite and kaolinite, as well as pressure solution of quartz grains. Smectite, commonly derived from alteration of volcanic rock fragments, may have been the primary clay mineral precursor of chlorite. In addition, authigenic kaolinite is closely associated with feldspar dissolution, suggesting that alteration of detrital feldspar grains was the most probable source for authigenic kaolinite. With the increase in temperature and consumption of organic acids, the ratio of K+/H+ increases and the stability field of kaolinite is greatly reduced, thereby transforming kaolinite into mixed layer illite/smectite and illite. Within the study area, porosity increases with chlorite content up to approximately 3% volume and then decreases slightly, indicating that chlorite coatings are beneficial at an optimum volume of 3%. A benefit of the dissolution of unstable minerals and feldspar grains is the occurrence of secondary porosity, which may enhance porosity to some extent. However, the solutes cannot be transported over a large scale in the deep burial environment, and simultaneous precipitation of byproducts of feldspar dissolution such as authigenic kaolinite and quartz cement will occur in situ or in adjacent pores, resulting in heterogeneity of the reservoirs.
Design, Synthesis and Biological Evaluation of Novel Coumarin-Based Hydroxamate Derivatives as Histone Deacetylase (Hdac) Inhibitors with Antitumor Activities
Authors: Yang Feifei , Zhao Na , Song Jiali , Zhu Kongkai , Jiang Cheng-shi , Shan Peipei , Zhang Hua
Published: July 2019

A series of novel coumarin-based hydroxamate derivatives were designed and synthesized as histone deacetylase inhibitors (HDACis). Selective compounds showed a potent HDAC inhibition with nM IC50 values, with the best compound (10e) being nearly 90 times more active than vorinostat (SAHA) against HDAC1. Compounds 10e and 11d also increased the levels of acetylated histone H3 and H4, which is consistent with their strong HDAC inhibition. In addition, 10e and 11d displayed a higher potency toward human A549 and Hela cancer cell lines compared with SAHA. Moreover, 10e and 11d significantly arrested A549 cells at the G2/M phase and enhanced apoptosis. Molecular docking studies revealed the possible mode of interaction of compounds 10e and 12a with HDAC1. Our findings suggest that these novel coumarin-based HDAC inhibitors provide a promising scaffold for the development of new potential cancer chemotherapies.
β-Peltoboykinolic Acid from Astilbe rubra Attenuates TGF-β1-Induced Epithelial-to-Mesenchymal Transitions in Lung Alveolar Epithelial Cells
Authors: Bang In Jae , Kim Ha Ryong , Jeon Yukyoung , Jeong Mi Ho , Park Yong Joo , Kwak Jong Hwan , Chung Kyu Hyuck
Published: July 2019

Epithelial-to-mesenchymal transition (EMT) is increasingly recognized as contributing to the pathogenesis of idiopathic pulmonary fibrosis. Therefore, novel plant-based natural, active compounds have been sought for the treatment of fibrotic EMT. The aim of the present study was to investigate the inhibitory effects of Astilbe rubra on TGF-β1-induced EMT in lung alveolar epithelial cells (A549). A. rubra was subjected to extraction using 70% ethanol (ARE), and ethanol extracts of the aerial part and that of the rhizome were further partitioned using various solvents. Protein expression and cell motility were investigated to evaluate the inhibitory effects of ARE on EMT. EMT occurred in A549 cells treated with TGF-β1, but was prevented by co-treatment with ARE. The dichloromethane fractions showed the strongest inhibitory effect on TGF-β1-induced EMT. β-Peltoboykinolic acid was isolated from the dichloromethane fractions of A. rubra by activity-oriented isolation. β-Peltoboykinolic acid not only attenuated TGF-β1-induced EMT, but also the overproduction of extracellular matrix components including type I collagen and fibronectin. The Smad pathway activated by TGF-β1 was inhibited by co-treatment with β-peltoboykinolic acid. Taken together, these results indicate that β-peltoboykinolic acid from A. rubra and dichloromethane fractions shows potential as an antifibrotic agent in A549 cells treated with TGF-β1.
Virus-Incorporated Biomimetic Nanocomposites for Tissue Regeneration
Authors: Raja Iruthayapandi Selestin , Kim Chuntae , Song Su-Jin , Shin Yong Cheol , Kang Moon Sung , Hyon Suong-Hyu , Oh Jin-Woo , Han Dong-Wook
Published: July 2019

Owing to the astonishing properties of non-harmful viruses, tissue regeneration using virus-based biomimetic materials has been an emerging trend recently. The selective peptide expression and enrichment of the desired peptide on the surface, monodispersion, self-assembly, and ease of genetic and chemical modification properties have allowed viruses to take a long stride in biomedical applications. Researchers have published many reviews so far describing unusual properties of virus-based nanoparticles, phage display, modification, and possible biomedical applications, including biosensors, bioimaging, tissue regeneration, and drug delivery, however the integration of the virus into different biomaterials for the application of tissue regeneration is not yet discussed in detail. This review will focus on various morphologies of virus-incorporated biomimetic nanocomposites in tissue regeneration and highlight the progress, challenges, and future directions in this area.
Hydrothermal Synthesis of SnO2 Nanoneedle-Anchored NiO Microsphere and its Gas Sensing Performances
Authors: Wei Zhijie , Zhou Qu , Wang Jingxuan , Lu Zhaorui , Xu Lingna , Zeng Wen
Published: July 2019

In this study, we reported a successful synthesis of a nanocomposite based on SnO2 nanoneedles anchored to NiO microsphere by a simple two-step hydrothermal route. The results show that the SnO2/NiO nanocomposite-based sensor exhibits more prominent performances than the pristine NiO microsphere to NO2 such as larger responses and more outstanding repeatability. The improved properties are mainly attributed to the p–n heterojunctions formed at the SnO2–NiO interface, leading to the change of potential barrier height and the enlargement of the depletion layer. Besides, the novel and unique nanostructure provides large and effective areas for the surface reaction. In addition, a plausible growth mechanism and the enhanced sensing mechanism were proposed to further discuss the special nanostructure which will benefit the exploration of high-performance sensors.
Do Bioreactor Designs with More Efficient Oxygen Supply to Ovarian Cortical Tissue Fragments Enhance Follicle Viability and Growth In Vitro?
Authors: Catapano Gerardo , Fragomeni Gionata , Falvo D’Urso Labate Giuseppe , De Napoli Luigi , Barbato Vincenza , Di Nardo Maddalena , Costanzo Valentina , Capriglione Teresa , Gualtieri Roberto , Talevi Riccardo
Published: July 2019

Background: Autotransplantation of cryopreserved ovarian tissue is currently the main option to preserve fertility for cancer patients. To avoid cancer cell reintroduction at transplantation, a multi-step culture system has been proposed to obtain fully competent oocytes for in vitro fertilization. Current in vitro systems are limited by the low number and health of secondary follicles produced during the first step culture of ovarian tissue fragments. To overcome such limitations, bioreactor designs have been proposed to enhance oxygen supply to the tissue, with inconsistent results. This retrospective study investigates, on theoretical grounds, whether the lack of a rational design of the proposed bioreactors prevented the full exploitation of follicle growth potential. Methods: Models describing oxygen transport in bioreactors and tissue were developed and used to predict oxygen availability inside ovarian tissue in the pertinent literature. Results: The proposed theoretical analysis suggests that a successful outcome is associated with enhanced oxygen availability in the cultured tissue in the considered bioreactor designs. This suggests that a rational approach to bioreactor design for ovarian tissue culture in vitro may help exploit tissue potential to support follicle growth.
A Numerical Approach to Solve Volume-Based Batch Crystallization Model with Fines Dissolution Unit
Authors: Mukhtar Safyan , Sohaib Muhammad , Ahmad Ishfaq
Published: July 2019

In this article, a numerical study of a one-dimensional, volume-based batch crystallization model (PBM) is presented that is used in numerous industries and chemical engineering sciences. A numerical approximation of the underlying model is discussed by using an alternative Quadrature Method of Moments (QMOM). Fines dissolution term is also incorporated in the governing equation for improvement of product quality and removal of undesirable particles. The moment-generating function is introduced in order to apply the QMOM. To find the quadrature abscissas, an orthogonal polynomial of degree three is derived. To verify the efficiency and accuracy of the proposed technique, two test problems are discussed. The numerical results obtained by the proposed scheme are plotted versus the analytical solutions. Thus, these findings line up well with the analytical findings.
Dowling, P.; et al. Characterization of Contractile Proteins from Skeletal Muscle Using Gel-Based Top-Down Proteomics. Proteomes 2019, 7, 25
Authors: Dowling Paul , Zweyer Margit , Swandulla Dieter , Ohlendieck Kay
Published: July 2019

The authors wish to make the following correction to their paper [...]
Clonal Evolution of B-Cell Acute Lymphoblastic Leukemia with del(9)(p13p21) into Mixed Phenotype Acute Leukemia Presenting as an Isolated Testicular Relapse
Authors: Miller Lane H. , Park Sunita I. , Saxe Debra , Lew Glen , Raikar Sunil S.
Published: July 2019

Lineage switch in acute leukemias is a well-reported occurrence; however, most of these cases involve a switch from either lymphoid to myeloid or myeloid to lymphoid lineage. Here, we report a case of a 14-year-old male with B-cell acute lymphoblastic leukemia (B-ALL) who initially responded well to standard chemotherapy but then later developed mixed phenotype acute leukemia (MPAL) at relapse, likely reflecting a clonal evolution of the original leukemia with a partial phenotypic shift. The patient had a del(9)(p13p21) in his leukemia blasts at diagnosis, and the deletion persisted at relapse along with multiple additional cytogenetic aberrations. Interestingly, the patient presented with an isolated testicular lesion at relapse, which on further analysis revealed both a lymphoid and myeloid component. Unfortunately, the patient did not respond well to treatment at relapse and eventually succumbed to his disease. To our knowledge, an isolated extramedullary MPAL at relapse in a patient with previously diagnosed B-ALL has not been reported in the literature before.
A Qualitative Investigation of Young Footballers’ Perceptions Regarding Developmental Experiences
Authors: Gerabinis Panagiotis , Goudas Marios
Published: July 2019

This study examined perceptions of Greek young football players regarding sport-related developmental experiences using a model of PYD through sport based on results from a qualitative study as a theoretical framework. Twenty one young football athletes (aged 12–15) gave semi-structured interviews. The young athletes identified both positive and negative developmental experiences related to the behaviors of coaches, parents and peers. They did not report any explicit teaching of life-skills. However, young footballers identified their life-skills development by implicit processes. Nevertheless, their understanding of life-skills was rather simplistic.
An Improved Bat Algorithm Based on Lévy Flights and Adjustment Factors
Authors: Li Yu , Li Xiaoting , Liu Jingsen , Ruan Ximing
Published: July 2019

This paper proposed an improved bat algorithm based on Lévy flights and adjustment factors (LAFBA). Dynamically decreasing inertia weight is added to the velocity update, which effectively balances the global and local search of the algorithm; the search strategy of Lévy flight is added to the position update, so that the algorithm maintains a good population diversity and the global search ability is improved; and the speed adjustment factor is added, which effectively improves the speed and accuracy of the algorithm. The proposed algorithm was then tested using 10 benchmark functions and 2 classical engineering design optimizations. The simulation results show that the LAFBA has stronger optimization performance and higher optimization efficiency than basic bat algorithm and other bio-inspired algorithms. Furthermore, the results of the real-world engineering problems demonstrate the superiority of LAFBA in solving challenging problems with constrained and unknown search spaces.
Outcomes of hospital admissions among frail older people: a 2-year cohort study
Authors: Keeble Eilís , Roberts Helen C , Williams Christopher D , Van Oppen James , Conroy Simon Paul
Published: July 2019

Background

‘Frailty crises’ are a common cause of hospital admission among older people and there is significant focus on admission avoidance. However, identifying frailty before a crisis occurs is challenging, making it difficult to effectively target community services. Better longer-term outcome data are needed if services are to reflect the needs of the growing population of older people with frailty.

Aim

To determine long-term outcomes of older people discharged from hospital following short (<72 hours) and longer hospital admissions compared by frailty status.

Design and setting

Two populations aged ≥70 years discharged from hospital units: those following short ‘ambulatory’ admissions (<72 hours) and those following longer inpatient stays.

Method

Data for 2-year mortality and hospital use were compared using frailty measures derived from clinical and hospital data.

Results

Mortality after 2 years was increased for frail compared with non-frail individuals in both cohorts. Patients in the ambulatory cohort classified as frail had increased mortality (Rockwood hazard ratio 2.3 [95% confidence interval {CI} = 1.5 to 3.4]) and hospital use (Rockwood rate ratio 2.1 [95% CI = 1.7 to 2.6]) compared with those patients classified as non-frail.

Conclusion

Individuals with frailty who are discharged from hospital experience increased mortality and resource use, even after short ‘ambulatory’ admissions. This is an easily identifiable group that is at increased risk of poor outcomes. Health and social care systems might wish to examine their current care response for frail older people discharged from hospital. There may be value in a ‘secondary prevention’ approach to frailty crises targeting individuals who are discharged from hospital.
Workload impact of the Quality and Outcomes Framework for patients with diabetes: an interrupted time series in general practice
Authors: Gilbert Claire , Allgar Victoria , Doran Tim
Published: July 2019

Background

There are substantial concerns about GP workload. The Quality and Outcomes Framework (QOF) has been perceived by both professionals and patients as bureaucratic, but the full impact of the QOF on GP workload is not well known.

Aim

To assess the impact of the QOF on GP consultation rates for patients with diabetes mellitus.

Design and setting

This study used interrupted time series of 13 248 745 general practice consultations for 37 065 patients with diabetes mellitus in England.

Method

Clinical Practice Research Datalink general practice data were used from 2000/2001 to 2014/2015, with introduction of the QOF (1 April 2004) as the intervention, and mean annual GP consultation rates as the primary outcome.

Results

Mean annual GP clinical consultation rates were 8.10 per patient in 2000/2001, 6.91 in 2004/2005, and 7.09 in 2014/2015. Introduction of the QOF was associated with an annual change in the trend of GP clinical consultation rates of 0.46 (95% confidence interval [CI] = 0.23 to 0.69, P = 0.001) consultations per patient, giving a post-QOF trend increasing by 0.018 consultations per year. Introduction of the QOF was associated with an immediate stepped increase of ‘other’ out-of-hours and non-clinical encounters, and trend change of 0.57 (95% CI = 0.34 to 0.81, P<0.001) per year, resulting in a post-QOF trend increasing by 0.27 other encounters per year.

Conclusion

Introduction of the QOF was associated with a modest increase in clinical GP consultation rates and substantial increase in other encounters for patients with diabetes independent of changes in diabetes prevalence. National prevalence of diabetes increased by 90.7% from 2004/2005 to 2014/2015, which, combined with this study’s findings, means GPs would have provided nearly double the number of consultations for patients with diabetes over this timescale.
ANALISIS DAMPAK PENINGKATAN KAPASITAS BRODO FOOTWEAR TERHADAP BIAYA RELEVAN DAN UTILITAS STATION KERJA DI CV MARASABESSY DENGAN MODEL SIMULASI KEJADIAN DISKRIT
Authors: Mulyani Mulyani , Santosa Alam
Published: July 2019

Tujuan dari penelitian ini adalah menemukan solusi untuk peningkatan kapasitas produksi dengan melihat dampak terhadap biaya relevan dan utilitas station kerja. Alternatif solusi dikembangkan melalui eksperimen terhadap model simulasi sistem produksi perusahaan menggunakan metode simulasi kejadian diskrit, dengan tahapan mengidentifikasi data struktur dan data numerik, membuat model, melakukan eksperimen, dan menyajikan hasil analisis. Pada tahap eksperimen didapatkan 11 skenario yang mungkin diterapkan oleh perusahaan dengan kommbinasi penambahan jam kerja dan perbaikan tata letak pabrik. Hasil yang diperoleh pada model aktual adalah 81 pasang/hari, jumlah ini dibawah permintaan perhari, solusi yang diterapkan perusahaan adalah menambah jam lembur. Hasil eksperimen pada skenario 3 sampai 8 diperoleh hasil produksi 80 sampai 103 pasang/hari, ini menunjukan peningkatan dari model aktual namun masih dibawah permintaan 100 pasang/hari, sedangkan hasil pada skenario 9 sampai 11 diperoleh hasil produksi 155 sampai 159 pasang/hari, ini menunjukan bahwa jumlah produk sudah diatas permintaan. Setiap skenario tersebut dapat digunakan oleh perusahaan untuk memenuhi permintaan yang berfluktuasi. Disimpulkan bahwa jika permintaan kurang dari 80 pasang, perusahaan dapat menggunakan model aktual dengan hasil 81 pasang/hari dan biaya Rp. 32.000 per pasang sedangkan permintaan antara 82 – 106, direkomendasikan menggunakan skenario 3 dengan hasil 106 pasang/hari denganbiaya Rp. 44.908/pasang, dan jika permintaan lebih dari 106 perusahaan dapat menggunakan skenario 9 dengan hasil 155 pasang/hari dan biaya Rp. 32.000. Utilitas stasiun kerja pada setiap skenario berkisar 26% hingga 89%.
ANALISIS PERILAKU KONSUMEN MIE INSTAN DENGAN MENGGUNAKAN ANALISIS MARKOV
Authors: Anthara Made Aryantha
Published: July 2019

Persediaan merupakan suatu masalah yang harus dikendalikan. Persedian barang di toko untuk penjualan ataupun persediaan bahan baku untuk produksi. Banyak toko ataupun perusahaan yang tidak melakukan proses pengendalian masalah dengan baik dalam pengelolaan persediaan. Persediaan barang sangat diperlukan karena pengadaan barang dibutuhkan waktu untuk proses pemesanaan atau pembelian.Persediaan suatu barang di toko, menjadi salah satu hal yang dapat menpengaruhi perilaku konsumen dalam mengkonsumsi sebuah produk. Jika produk yang dibutuhkan tidak tersedia atau stoknya habis, maka hal ini bisa membuat konsumen untuk beralih ke produk sejenis namun dengan merk yang berbeda

 

Produk yang dijadikan objek penelitian adalah produk mie instan yang banyak beredar di pasaran. Dasar pemilihan produk ini adalah dikatenakan produk ini banyak ditemukan di pasaran dan konsumennya dapat dikatakan banyak. Ada tiga merk mie instan yang akan dianalisis dalam penelitian ini. Dalam penelitian ini juga akan diketahui bagaimana perilaku konsumen terhadap pemenuhan kebutuhan mie instan dalam satu periode tertentu.

 

Untuk merencakan persediaan di toko diperlukan suatu metode, salah satu metode yang dapat dipakai yaitu rantai markov. Rantai markov (markov chain) dikembangkan oleh seorang ahli Rusia A.A. Markov pada tahun 1896 dimana merupakan suatu metode yang mempelajari sifat-sifat suatu variabel pada masa sekarang yang didasarkan pada sifat-sifatnya di masa lalu dalam usaha menaksir sifat-sifat variabel tersebut dimasa yang akan datang. Dalam penelitian ini diperoleh hasil bahwa perpindahan terbesar untuk pembelian mie instan terjadi pada konsumen Sarimi yang berpindah untuk membeli mie instan merk Indomie yaitu sebesar 83% sedangkan untuk kondisi steady state diperoleh bahwa konsumen akan tetap dalam pilihan membeli satu merk mie instan terdapat pada bulan ke -4
USULAN PERANCANGAN TATA LETAK FASILITAS LANTAI PRODUKSI MENGGUNAKAN ALGORITMA CRAFT DI PABRIK ALUMUNIUM SUPER (CAP KOMODO)
Authors: Andriani Diana , Maskur Agung Arief
Published: July 2019

Perancangan tata letak fasilitas lantai produksi dalam penelitian ini bertujuan untuk menyelesaikan permasalahan di lantai produksi yaitu letak departemen satu dengan departemen lainnya yang letaknya berjauhan berdasarkan aliran produksi.  Departemen tersebut yaitu receiving dengan peleburan dan pengikiran dengan perakitan. Metode yang digunakan untuk menyelesaikan permasalahan dalam penelitian ini yaitu Algoritma CRAFT. Metode ini dipilih karena dapat melakukan pertukaran antar departmen dan melakukan pemindahan departemen sehingga departemen yang bejauhan dapat kembali berdekatan. Selain itu juga adanya departemen yang fix atau tidak dapat dipindahkan. Departemen fix tersebut yaitu peleburan dan gudang bahan jadi (shipping). Hasil yang  diperoleh setelah dilakukan perbaikan pada tata letak lantai produksi menggunakan algoritma CRAFT dengan bantuan software WINQSB di Pabrik Alumunium Super (Cap Komodo yaitu permutasi yang menghasilkan 233 pilihan alternatif layout usulan. Layout yang terpilih menghasilkan tata letak yang sama yaitu pada layout 1, 8, 9, 30, 31 dan 83.

Layout ini menghasilkan tata letak departemen bahan baku (receiving) yang menjadi berdekatan dengan peleburan serta lokasi pengikiran yang menjadi berdekatan dengan perakitan. Total Ongkos Material Handling awal yaitu Rp 5960,77, maka total Ongkos Material Handling  layout usulan CRAFT lebih rendah yaitu dengan total sebesar                     Rp 4021,68 per satu kali frekuensi perpindahan material.
USULAN PENJADWALAN PERGANTIAN KOMPONEN PADA MESIN FILLING MULTILINE MENGGUNAKAN MODEL AGE REPLACEMENT DAN BLOCK REPLACEMENT DI PT IKAFOOD PUTRAMAS
Authors: Sianturi Gabriel , Imaduddin Azka Fauzan Hafizh
Published: July 2019

Pada zaman sekarang, penggunaan mesin pada perusahaan sudah banyak diterapkan untuk meningkatkan kualitas dan kuantitas produksi. Hal tersebut dilakukan perusahaan agar produknya dapat bersaing serta dapat memenuhi kebutuhan pasar. Kelancaran suatu proses produksi sangatlah bergantung pada baik atau tidaknya kondisi mesin yang akan digunakan. Salah satu hambatan pada mesin salah satunya ada di bagian komponen yang mengalami kerusakan sehingga mesin tidak dapat bekerja dengan baik. PT. IKAFOOD PUTRAMAS merupakan suatu perusahaan yang memproduksi bumbu-bumbu masakan dan macam-macam saus. Pada bagian proses filling, PT. IKAFOOD PUTRAMAS sudah menggunakan mesin otomatis yaitu mesin filling multiline. PT. IKAFOOD PUTRAMAS saat ini tidak mempunyai jadwal pergantian khusus untuk suatu komponen, maka dari itu penggantian komponen hanya dilakukan saat terjadinya kerusakan pada komponen tersebut. Kondisi tersebut berdampak pada terjadinya kerusakan komponen saat sedang digunakan yang mempengaruhi kuantitas dan kualitas dari produk yang dihasilkan. Penjadwalan pergantian komponen merupakan solusi yang tepat untuk mengatasi permasalah tersebut. Jadwal pergantian komponen dapat dicari menggunakan model age replacement dan block replacement. Model pergantian ini berguna untuk menentukan interval waktu penggantian komponen berdasarkan data histori kerusakan yang telah terjadi. Hasil dari penelitian adalah komponen seal piston mempunyai interval waktu pergantian selama lima hari sekali dengan biaya pergantian Rp. 20.740 untuk age replacement dan lima hari sekali dengan biaya pergantian Rp. 20.015 untuk block replacement. Komponen lainnya adalah heater horizontal mempunyai interval waktu pergantian selama 47 hari sekali dengan biaya pergantian Rp. 401.239 untuk age replacement dan 48 hari sekali dengan biaya pergantian Rp. 405.696 untuk block replacement.
PERHITUNGAN WAKTU BAKU DAN SIMULASI ALIRAN PROSES PRODUK SPARE PART DI CV. GRAND MANUFACTURING INDONESIA
Authors: Riyanto Agus , Sofyan Dilan Ramadhan
Published: July 2019

Grand Manufacturing Indonesia adalah perusahaan yang memproduksi produk spare part yang dihasilkan dengan berbagai macam produk spare part kendaraan roda dua. Perusahaan sangat membutuhkan adanya pengukuran waktu kerja yang tepat untuk menargetkan produksi yang dapat dijadikan salah satu tujuan untuk memenuhi kebutuhan konsumen.

 

Perusahaan akan menghadapi persoalan yang berhubungan dengan pencapaian permintaan konsumen agar terpenuhi, terkadang target yang ditetapkan tidak dapat terpenuhi karena kurang sesuai. Ketidakpastian waktu kerja yang berakibat tidak pastimya produk yang dihasilkan oleh perusahaan untuk memenuhi pemintaan, sedangkan konsumen meminta perusahaan memasok produk sekali pengiriman 3000-4000 per minggu terkadang  delapan hari baru terkirim dikarena belum mencapai target. Agar mendapatkan waktu yang sangat efektif dan efesien terhadap perusahaan.

 

Dalam penelitian ini pengukuran dengan metode work sampling digunakan untuk menghitung waktu baku, dan untuk menentukan faktor penyesuaian digunakan secara objektif. Beberapa langkah untuk memperoleh waktu baku dari satu siklus dari proses pembuatan saringan oli melakukan pengukuran, penentuan faktor kelonggaran dan menghitung waktu siklus serta waktu normal. yang dihasilkan operator serta waktu penyesuaian selama waktu operator bekerja dan waktu baku dari setiap operasi”kerja.

 

Hasil penelitian menunjukan waktu”baku”total”adalah 198,77”detik”(3,31menit). Hasil untuk”simulasi dari ”promodel ”menujukan ” produk yang dihasilkan adalah 373 perhari sedangkan target perusahan dalam satu minggu 3000-4000 satu kali pengiriman sehingaa tidak bisa memenuhi waktu yang ditetapkan oleh konsumen. Perusahan harus segera” mengambil keputusan” untuk” memperbaiki”  lantai produksi”dan”adanya evaluasi kerja”operator agar”target”produksi tercapai.
Para pensar a cultura na periferia do capitalismo / Thinking culture on the periphery of capitalism
Authors: Kropf Paula
Published: July 2019

O presente texto procura discutir relações entre cultura e forma social. Para tal percurso, buscamos abordar a seguinte questão: a cultura, como prática social - tomando a compreensão do marxista britânico Raymond Williams - pode ser configurada como um elemento anti-barbárie na periferia do capitalismo, conforme debate Schwarz (1999). A compreensão das relações sociais, aqui, se encontra angulada pela tonalidade destrutiva inerente à lógica capitalista, que caminha em direção a um estado de regressão acentuado sem precedentes. Trata-se de um sistema centrado na produção de mercadorias que contém a sua dissolução por meio da violência. É possível o cultivo das potencialidades humanas quando estamos amalgamados e movidos por algo – a valorização do valor – que é contraditória às tendências de emancipação?
Homenagem: Homenagem a José Paulo Netto Entrega da Medalha Pedro Ernesto / Tribute to José Paulo Netto Delivery of the Pedro Ernesto Medal
Authors: Iamamoto Marilda
Published: July 2019

Gostaria de saudar a iniciativa do mandato do vereador Renato Cinco do PSOL-RJ pela homenagem a José Paulo Netto, concedendo-lhe a medalha Pedro Ernesto, a maior Honraria da Câmara dos Vereadores do Rio de Janeiro, neste dia 07 de novembro, exatamente nos 100 anos da Revolução Russa. Estas comemorações são também dos 70 anos de vida intensamente vividos de nosso homenageado, comemorados em 29 de novembro.
Questão ambiental, lutas sociais e agroecologia: a luta por território no Engenho Ilha/Pernambuco / Environmental issues, social struggles and agroecology: the struggle for territory in Engenho Ilha / Pernambuco
Authors: Silva Maria das Graças e , Grossi Mônica , Silva Rebeca Gomes de Oliveira , Prazeres Amanda Rayza Brito dos , Domingues Vera Lucia
Published: July 2019

Este artigo pretende discutir a relação entre questão ambiental, lutas sociais e agroecologia, no contexto de crise do capital. Ao intensificar a exploração dos trabalhadores, o capital avança sobre os recursos naturais e bens comuns, exacerbando suas contradições e gerando uma série de conflitos no campo e na cidade. Os chamados conflitos socioambientais, em defesa do acesso e posse da terra e/ou de recursos naturais, vêm se generalizando. Destacamos, para efeito deste artigo, a experiência de luta da Associação de Pequenos Agricultores de Ponte dos Carvalhos, município do Cabo de Santo Agostinho - Pernambuco e sua luta em defesa do território, da preservação do modo de vida dos moradores da área; em relevo também as estratégias de fortalecimento político-organizativo e econômicas, tendo como referência a agroecologia.
Assistentes sociais, saber e identidade: reflexões sobre um processo de investigação etnográfica / Social workers, knowledge and identity: reflections on a ethnographic research process
Authors: Granja Berta
Published: July 2019

A comunicação apresenta um processo de investigação etnográfica sobre o saber agir profissional dos Assistentes Sociais, saber que é aqui considerado como uma componente fundamental da sua identidade. Descreve o processo de construção do objeto e da metodologia e aborda os problemas de gestão das relações sociais de observação no que diz respeito aos profissionais mas, também, relativamente às pessoas que com ele interagiam na vida quotidiana das instituições sociais. Apresenta os diferentes tipos de dados recolhidos e a complexidade da sua categorização, análise e tratamento. São, ainda, analisadas as possibilidades e limites deste processo de investigação etnográfica e as condições implementadas para o necessário controlo epistemológico.
Estudo socioeconômico: atribuição privativa do serviço social? / Socioeconomic study: private assignment of social service?
Authors: Pedroso Andreia Pereira
Published: July 2019

Este artigo trata-se de uma explanação sobre as divergências que cercam os estudos socioeconômicos, que dividem opiniões dos profissionais do serviço social sobre ser ou não atribuição privativa da categoria. Esta discussão foi realizada no âmbito do Instituto Federal de Educação Ciência e Tecnologia do Rio Grande do Sul, dadas as atividades que se colocam para esta categoria neste meio, mas não houve consenso. No entanto, o assunto foi debatido anteriormente, em outros âmbitos e para o Conselho Federal do serviço social, assim como para as autoras estudadas para o presente artigo, o estudo socioeconômico trata-se de atribuição privativa.
Entrevista - Mineração e crise do capital
Authors: Pontes Nicole Alves Espada
Published: July 2019

A discussão dessa temática acontece em entrevista com Márcio Zonta, formado em Jornalismo e Relações Públicas, com especialização em estudos latino-americanos. Há aproximadamente 10 anos iniciou seu trabalho como jornalista para o “Brasil de Fato”, com a cobertura de violência policial em favelas de São Paulo e, posteriormente, tornou-se correspondente do jornal no Pará, no Maranhão e no Peru – três regiões fortemente marcadas pelo processo minerador, levando-o a se debruçar sobre o tema da mineração e suas mazelas na América Latina.  Em meados de 2013, ao retornar da cobertura dos conflitos na mineração norte peruana, se integrou ao coletivo de sujeitos que formulavam a elaboração do movimento brasileiro que hoje é reconhecido como MAM: Movimento Pela Soberania Popular na Mineração, do qual ocupa a coordenação nacional atualmente.
A reforma da contrarreforma agrária no Brasil / The reform of the agrarian counter-reform in the Brazil
Authors: Firmiano Frederico Daia , Mafort Kelli Cristine de Oliveira
Published: July 2019

Este artigo tem por objetivo analisar as políticas do atual governo Temer para a reforma agrária. Seu argumento central é que, ancorado nas condições políticas e econômicas do golpe, as medidas de Temer para o campo possuem um caráter mais acelerado e agressivo de regressão dos direitos, marcado por continuidades com relação aos governos do PT. Busca-se demonstrar que, ao promover os agronegócios e em alguma medida a agricultura familiar, abandonando a possibilidade de uma política massiva de assentamento rural de novas famílias no país, Lula da Silva praticou uma contrarreforma agrária, que sob o governo Dilma Rousseff foi aprofundada, em face da crise econômica que a levou a produzir severos cortes nos gastos públicos, particularmente, nos incentivos que vinham sendo destinados para a agricultura familiar. Tal reforma, agora, tem sido levada às últimas consequências por Temer. A isto chamou-se de reforma da contrarreforma agrária.
Um Rio de Janeiro feérico e decadente
Authors: Taddei Brandini Laura
Published: July 2019

O presente artigo tem por objetivo analisar o olhar do escritor francês Gilles Lapouge sobre o Rio de Janeiro a partir da leitura do verbete dedicado à cidade em seu Dictionnaire Amoureux du Brésil, publicado em 2011. Os diálogos com outros escritores-viajantes que conheceram o Rio, como Stefan Zweig, ou com o escritor que buscava, no tema da viagem, evadir-se da realidade, Baudelaire, conduzem a construção da imagem da cidade para Lapouge, oscilando entre um Rio de Janeiro feérico e decadente.
Favela e floresta – escritas de periferias brasileiras
Authors: Rothier Cardoso Marília
Published: July 2019

Nas últimas décadas, escritas das margens da sociedade moderna organizada e do cânone literário erudito começaram a circular entre os leitores, apresentando novos escritores desconhecidos até então. Este artigo comenta algumas narrativas coletadas na floresta tropical por índios que falam tanto sua língua nativa quanto português. Em paralelo, estuda estórias construídas na periferia das grandes cidades cujo tema é o modo de vida nas favelas. O fundo mítico destas vem principalmente da cultura ioruba herdada por muitos afrodescendentes. A leitura comparativa de tal seleção de textos traz argumentos para discutir conceitos e valores ocidentais, como antropocentrismo, preconceitos machistas e premissas centrais do racionalismo moderno. Outros aspectos observados são as marcas da tradição oral no estilo narrativo e a presença de personagens fantásticas como meio de explicar fenômenos naturais. Alguns textos buscaram publicação apenas para preservar saberes arcaicos, outros construíram-se com o intuito de produzir efeito artístico. Esses últimos usam o português como se fosse uma língua estrangeira misteriosa.
A carta entre a esfera da memória e da história: José de Alencar escreve a D. Pedro II
Authors: Brandão Mendes Moema Rodrigues , De Mattos Revelino Leonardo Pires
Published: July 2019

RESUMO:Esta reflexão propõe, por meio do caráter interdisciplinar, agregar a relação entre Epistolografia e História sob o aporte da Memória. O dossiê missivístico consultado é constituído por 32 cartas enviadas por José de Alencar a D. Pedro II no período de 1868 a 1870. O objeto eleito para esta reflexão é 1 carta deste lote, sem data que apresentou um caráter híbrido transitando entre o pessoal e o institucional haja vista que Alencar, o literato, ocupou o lugar de Ministro da Justiça, o político, em cujo período enviou esta carta ao referido Imperador. A correspondência tratada encontra-se sob a custódia do Arquivo Histórico do Museu Imperial de Petrópolis (AHMIP-RJ) e disponível à pesquisa pública e, para efeito de critério, esta correspondência classifica-se como ativa a partir do envio do remetente em questão. O desenvolvimento desta reflexão valeu-se da modalidade qualitativa, com apoio metodológico de natureza histórica e documental, em base bibliográfica exploratória e virtual. Este estudo é uma ação do Projeto Arquivos literários: memória, resgate, preservação, devidamente certificado pelo CNPq que propõe historiar a correspondência em questão, situá-la no tempo e no espaço e compreendê-la no campo da interdisciplinaridade como é o caso.
O avesso do bordado: Walter Benjamin, José Leonilson e Lu Menezes
Authors: Camêlo Francisco
Published: July 2019

Este artigo reflete sobre o gesto de bordar no trabalho do artista plástico José Leonilson e da poeta Lu Menezes, a partir do pensamento de Walter Benjamin sobre a infância e, em particular, sobre a imagem da “Caixa de costura” (Der Nähkasten), de Infância em Berlim por volta de 1900, que guarda ferramentas dadas às crianças como atividade iniciatória a escrita.