bluuebunny/crossref_metadata_2025 huggingface dataset:
EVALUASI TINGKAT KEPUASAN PASIEN TERHADAP PELAYANAN KEFARMASIAN DI KLINIK X MENGGUNAKAN APLIKASI E-SERVQUAL BERBASIS WEB
Authors: Rianto Leonov , Al'Qarana Gilang , Sabrina Alifa
Published: April 2020

In an effort to improve the quality of service, patient satisfaction can be measured by the SERVQUAL (SERVICE QUALITY) method by making a comprehensive customer satisfaction assessment survey for services in the field of goods and services that prioritize pharmaceutical services. Customer satisfaction analysis is based on five dimensions of service quality, namely responsiveness, reliability, assurance, empathy, and tangible. The formulation of the problem in this study wanted to find out how patient satisfaction with pharmacy services in clinic X. The purpose of this study was to describe patient satisfaction with pharmacy services in clinic X. Using descriptive quantitative methods to determine the level of patient satisfaction with pharmaceutical services using questionnaires as instruments Study data on patient visits were treated at 3 months beginning in 2018 in January 2,970 patients, February 2,868 patients, and March 3,304 patients. Based on data that has been recapitulated in a system by web-based e-SERVQUAL application and its validity has been tested, the percentage of each variable is evenly distributed in the range of 70%, on the dimensions of attitude and appearance. , 20% of patients were satisfied, in the dimension of drug waiting time, 73.90% of patients were satisfied, on the assurance dimension 74.45% of patients were satisfied, on the dimensions of empathy satisfied patients were 73.50%, on the dimensions of facilities and patient facilities were satisfied , 87%. From these results, the patient is satisfied with the overall dimensions of service, the greatest level of satisfaction is in the dimensions of attitude and appearance, and the smallest level of satisfaction is on the dimensions of facilities and facilities, it can be concluded that the percentage of 74.14% is in the predicate satisfied.
Volumetric Reconstructions of Found Footage: Stressing the Non-Identity of 3-D Replicas
Authors: Gonring Gabriel Menotti Miglio Pinto
Published: April 2020

This article examines the history and operational underpinnings of forms of volumetric reconstruction based on the capture of visual data, particularly photogrammetry. Photogrammetry is one of the chief techniques currently employed in the production of virtual replicas for heritage conservation and audiovisual production. The computational realism resulting from this process induces the belief that it is possible to recover the totality of an object from its medial traces. The author analyses how his work, as well as those of other artists, challenge this technological promise by exploring the formal idiosyncrasies of photogrammetric models.
ORAL REHABILITATION BY TWIN STAGE TECHNIQUE IN A CASE OF AMELOGENESIS IMPERFECTA
Authors: CHATTERJEE NIRMALYA , GHOSH AMRITA
Published: April 2020

Amelogenesis Imperfecta (AI) is a diverse collection of inherited diseases that exhibit quantitative or qualitative tooth enamel defects in the absence of systemic manifestations. It is necessary to diagnose the case and provide durable functional and aesthetic management of these patients, as the unaesthetic appearance has a definite negative psychological impact. This clinical report describes the use of the Hobo twin-stage procedure for rehabilitation of a patient with amelogenesis imperfecta and reduced vertical dimension of occlusion. The treatment plan was executed keeping in mind not only the severely damaged dentition but also treating the whole stomatognathic system. Utmost care was taken to achieve harmonious occlusion with no possible occlusal interferences which would otherwise initiate the habit of bruxism and thereby cause wear of the prosthesis. KEY WORDS : Amelogenesis Imperfecta , Hobo twin-stage procedure , harmonious occlusion .
Polymeric Planar Microcavities Doped with a Europium Complex
Authors: Lova Paola , Olivieri Marco , Surace Alba , Topcu Gokhan , Emirdag-Eanes Mehtap , Demir Mustafa , Comoretto Davide
Published: April 2020

Organo-metallic europium complex tetrakis (dibenzoyl methide) triethylammonium (EuD4TEA) shows a sharp emission spectrum, which makes it interesting for photonic applications. In this work, we embedded it into all-polymeric planar microcavities and investigated the effect of the photonic environment on its emission spectrum. To this end, submicron-sized EuD4TEA crystals were loaded into a blend of polystyrene and carboxylic terminated polystyrene matrix, which served to stabilize the emitter in the polymer and to make the composite processable. The new composite was then casted by spin-coating as a defect layer in a polymeric planar microcavity. Spectroscopic studies demonstrate that fine spectral tuning of the cavity mode on the sharp organometal luminescence is possible and produces spectral redistribution of the fluorophore emission, along with a remarkable cavity quality factor.
Non-Precious Metal Graphene-Based Catalysts for Hydrogen Evolution Reaction
Authors: Luis-Sunga Maximina , Regent Lana , Pastor Elena , García Gonzalo
Published: April 2020

Developing sustainable and renewable energy sources is critical as higher and higher global energy and environmental challenges arise. Hydrogen has the highest mass/energy density of any fuel and is considered one of the best sources of clean energy. Water splitting is regarded as one of the most promising solutions for hydrogen production on a large scale. Highly efficient, durable, and cost-effective catalysts for hydrogen evolution reaction (HER) are critical in the realization of this goal. Among the many materials proposed, graphene-based materials offer some unique properties for HER catalysis. In this review, we present recent progress on development of graphene-based electrocatalysts toward HER throughout the past few years.
Flexibility Evaluation Method of Power Systems with High Proportion Renewable Energy Based on Typical Operation Scenarios
Authors: Tang Xiangying , Hu Yan , Chen Zhanpeng , You Guangzeng
Published: April 2020

The development of renewable energy represented by wind, photovoltaic and hydropower has increased the uncertainty of power systems. In order to ensure the flexible operation of power systems with a high proportion of renewable energy, it is necessary to establish a multi-scenario power system flexibility evaluation method. First, this study uses a modified k-means algorithm to cluster operating scenarios of renewable energy and load to obtain several typical scenarios. Then, flexibility evaluation indices are proposed from three perspectives, including supply and demand balance of the zone, power flow distribution of the zone and transmission capacity between zones. Next, to calculate the flexibility evaluation indices of each scenario—and according to the occurrence probability of each scenario—we multiplied the indices of each scenario by the scenario occurrence probability to obtain comprehensive evaluation indices of all scenarios. Based on the actual historical output data of renewable energy and load of a southern power system in China, a flexibility evaluation was performed on the modified IEEE 14 system and modified IEEE 39 system. The results show that the proposed clustering method and flexibility indices can effectively reflect the flexibility status of the power system.
Correction: Shoombuatong, W., et al. iQSP: A Sequence-Based Tool for the Prediction and Analysis of Quorum Sensing Peptides via Chou’s 5-Steps Rule and Informative Physicochemical Properties. Int. J. Mol. Sci. 2020, 21, 75
Authors: Charoenkwan Phasit , Schaduangrat Nalini , Nantasenamat Chanin , Piacham Theeraphon , Shoombuatong Watshara
Published: April 2020

The authors wish to make the following corrections to this paper: [...]
The Effect of Nanosystems on ATP-Binding Cassette Transporters: Understanding the Influence of Nanosystems on Multidrug Resistance Protein-1 and P-glycoprotein
Authors: Mello Francisco V.C. , de Moraes Gabriela N. , Maia Raquel C. , Kyeremateng Jennifer , Iram Surtaj Hussain , Santos-Oliveira Ralph
Published: April 2020

The cancer multidrug resistance is involved in the failure of several treatments during cancer treatment. It is a phenomenon that has been receiving great attention in the last years due to the sheer amount of mechanisms discovered and involved in the process of resistance which hinders the effectiveness of many anti-cancer drugs. Among the mechanisms involved in the multidrug resistance, the participation of ATP-binding cassette (ABC) transporters is the main one. The ABC transporters are a group of plasma membrane and intracellular organelle proteins involved in the process of externalization of substrates from cells, which are expressed in cancer. They are involved in the clearance of intracellular metabolites as ions, hormones, lipids and other small molecules from the cell, affecting directly and indirectly drug absorption, distribution, metabolism and excretion. Other mechanisms responsible for resistance are the signaling pathways and the anti- and pro-apoptotic proteins involved in cell death by apoptosis. In this study we evaluated the influence of three nanosystem (Graphene Quantum Dots (GQDs), mesoporous silica (MSN) and poly-lactic nanoparticles (PLA)) in the main mechanism related to the cancer multidrug resistance such as the Multidrug Resistance Protein-1 and P-glycoprotein. We also evaluated this influence in a group of proteins involved in the apoptosis-related resistance including cIAP-1, XIAP, Bcl-2, BAK and Survivin proteins. Last, colonogenic and MTT (3-(4,5-dimethylthiazol-2-yl)- 2,5-diphenyltetrazolium bromide) assays have also been performed. The results showed, regardless of the concentration used, GQDs, MSN and PLA were not cytotoxic to MDA-MB-231 cells and showed no impairment in the colony formation capacity. In addition, it has been observed that P-gp membrane expression was not significantly altered by any of the three nanomaterials. The results suggest that GQDs nanoparticles would be suitable for the delivery of other multidrug resistance protein 1 (MRP1) substrate drugs that bind to the transporter at the same binding pocket, while MSN can strongly inhibit doxorubicin efflux by MRP1. On the other hand, PLA showed moderate inhibition of doxorubicin efflux by MRP1 suggesting that this nanomaterial can also be useful to treat MDR (Multidrug resistance) due to MRP1 overexpression.
Reduced Graphene Oxide-Based Impedimetric Immunosensor for Detection of Enterotoxin A in Milk Samples
Authors: Rocha Giovanna S. , Silva Martin K. L. , Cesarino Ivana
Published: April 2020

A simple, cheap, and less aggressive immobilization procedure for biomolecules using reduced graphene oxide (rGO) was employed to prepare an impedimetric immunosensor for detection of staphylococcal enterotoxin A (SEA) from Staphylococcus aureus in milk samples. The scanning electron microscopy, cyclic voltammetry, and electrochemical impedance spectroscopy (EIS) were used to monitor the single steps of the electrode assembly process. The glassy carbon (GC)/rGO platform detected the antigen-antibody binding procedures of SEA with concentrations of 0.5 to 3.5 mg L−1 via impedance changes in a low frequency range. The impedimetric immunosensor was successfully applied for the determination of SEA in milk samples.
Optimization the Process of Chemically Modified Carbon Nanofiber Coated Monolith via Response Surface Methodology for CO2 Capture
Authors: Malekbala Mohamad Rasool , Soltani Soroush , Abdul Rashid Suraya , Abdullah Luqman Chuah , Rashid Umer , Nehdi Imededdine Arbi , Choong Thomas Shean Yaw , Teo Siow Hwa
Published: April 2020

In the present study, a sequence of experiments was performed to assess the influence of the key process parameters on the formation of a carbon nanofiber-coated monolith (CNFCM), using a four-level factorial design in response surface methodology (RSM). The effect of reaction temperature, hydrocarbon flow rate, catalyst and catalyst promoter were examined using RSM to enhance the formation yield of CNFs on a monolith substrate. To calculate carbon yield, a quadratic polynomial model was modified through multiple regression analysis and the best possible reaction conditions were found as follows: a reaction temperature of 800 °C, furfuryl alcohol flow of 0.08525 mL/min, ferrocene catalyst concentration of 2.21 g. According to the characterization study, the synthesized CNFs showed a high graphitization which were uniformly distributed on a monolith substrate. Besides this, the feasibility of carbon dioxide (CO2) adsorption from the gaseous mixture (N2/CO2) under a range of experimental conditions was investigated at monolithic column. To get the most out of the CO2 capture, an as-prepared sample was post-modified using ammonia. Furthermore, a deactivation model (DM) was introduced for the purpose of studying the breakthrough curves. The CO2 adsorption onto CNFCM was experimentally examined under following operating conditions: a temperature of 30–50 °C, pressure of 1–2 bar, flow rate of 50–90 mL/min, and CO2 feed amount of 10–40 vol.%. A lower adsorption capacity and shorter breakthrough time were detected by escalating the temperature. On the other hand, the capacity for CO2 adsorption increased by raising the CO2 feed amount, feed flow rate, and operating pressure. The comparative evaluation of CO2 uptake over unmodified and modified CNFCM adsorbents confirmed that the introduced modification procedure caused a substantial improvement in CO2 adsorption.
C-S-H Pore Size Characterization Via a Combined Nuclear Magnetic Resonance (NMR)–Scanning Electron Microscopy (SEM) Surface Relaxivity Calibration
Authors: Naber Christoph , Kleiner Florian , Becker Franz , Nguyen-Tuan Long , Rößler Christiane , Etzold Merlin A. , Neubauer Jürgen
Published: April 2020

A new method for the nuclear magnetic resonance (NMR) surface relaxivity calibration in hydrated cement samples is proposed. This method relies on a combined analysis of 28-d hydrated tricalcium silicate samples by scanning electron microscopy (SEM) image analysis and 1H-time-domain (TD)-NMR relaxometry. Pore surface and volume data for interhydrate pores are obtained from high resolution SEM images on surfaces obtained by argon broad ion beam sectioning. These data are combined with T2 relaxation times from 1H-TD-NMR to calculate the systems surface relaxivity according to the fast exchange model of relaxation. This new method is compared to an alternative method that employs sequential drying to calibrate the systems surface relaxivity.
Is Initial Misdiagnosis Associated with Reaching Disability Milestones in Patients with Multiple Sclerosis?
Authors: Ivaniuk Alina , Marusich Tetiana , Solodovnikova Yuliia , Son Anatoliy
Published: April 2020

Background and objectives: multiple sclerosis (MS) is a chronic demyelinating disorder of the CNS with a variable course and disability progression. The latter may be prevented with disease-modifying therapy (DMT). Initial misdiagnosis may postpone the use of DMT. There are no studies to explore whether initial misdiagnosis is indeed associated with a higher rate of reaching disability in MS patients. We aimed to investigate the association between initial misdiagnosis and reaching disability milestones in relapsing-remitting MS (RR-MS) patients. Materials and methods: Data from 128 RR-MS patients were retrospectively reviewed. EDSS 4 and EDSS 6 were chosen as disability milestones as those associated with a significant decrease in ambulation. Survival analysis was used, and Kaplan–Meier curves were generated to investigate how initial misdiagnosis affects reaching the defined milestones. Results: 53 patients (41.4%, 31 females, 22 males) were initially misdiagnosed. Initially misdiagnosed patients had a lesser risk of reaching EDSS 4 up to 11 years and EDSS 6 up to 22 years from the onset than non-misdiagnosed patients (p = 0.22 and p = 0.25 correspondingly). Median time to reaching EDSS 4 and 6 was eight years (95% CI 0.0–17.6) and 10 years (95% CI 4.25–20.75) in misdiagnosed and three years (95% CI 0.0–20.0 years) and five years (95% CI 0.0–13.73 years) in non-misdiagnosed patients correspondingly. Conclusions: Initially misdiagnosed RR-MS patients tended to reach disability milestones later than non-misdiagnosed ones, which might reflect an intrinsically milder disease. Individuals presenting with mild or non-specific symptoms suspicious of MS, must be deliberately managed.
Effects of Bilberry Supplementation on Metabolic and Cardiovascular Disease Risk
Authors: Chan Sze Wa , Tomlinson Brian
Published: April 2020

Metabolic syndrome is a cluster of interrelated conditions that is associated with an increased risk of cardiovascular disease (CVD) and type 2 diabetes mellitus (T2DM). Oxidative stress may impair normal physiological functions, leading to various illnesses. T2DM is considered to be associated with increased oxidative stress, inflammation, and dyslipidemia, which may play a significant role in the development of cardiovascular complications, cancer and vision loss through cataracts and retinopathy. While conventional therapies are a cornerstone for the management of the major risk factors of metabolic syndrome, increasing antioxidant defense by increasing intake of antioxidant-rich foods may improve long term prospects in CVD, obesity and T2DM. Bilberry (Vaccinium myrtillus L.) is one of the richest natural sources of anthocyanins which give berries their red/purple/blue coloration. Anthocyanins are powerful antioxidants and are reported to play an important role in the prevention of metabolic disease and CVD as well as cancer and other conditions. This review focuses on the potential effects of bilberry supplementation on metabolic and cardiovascular risk factors. Although there is evidence to support the use of bilberry supplementation as part of a healthy diet, the potential benefits from the use of bilberry supplementation in patients with T2DM or CVD needs to be clarified in large clinical trials.
New Phosphine Oxides as High Performance Near- UV Type I Photoinitiators of Radical Polymerization
Authors: Dietlin Céline , Trinh Thanh Tam , Schweizer Stéphane , Graff Bernadette , Morlet-Savary Fabrice , Noirot Pierre-Antoine , Lalevée Jacques
Published: April 2020

Carbazole structures are of high interest in photopolymerization due to their enhanced light absorption properties in the near-UV or even visible ranges. Therefore, type I photoinitiators combining the carbazole chromophore to the well-established phosphine-oxides were proposed and studied in this article. The aim of this article was to propose type I photoinitiators that can be more reactive than benchmark phosphine oxides, which are among the more reactive type I photoinitiators for a UV or near-UV light emitting diodes (LED) irradiation. Two molecules were synthesized and their UV-visible light absorption properties as well as the quantum yields of photolysis and photopolymerization performances were measured. Remarkably, the associated absorption was enhanced in the 350–410 nm range compared to benchmark phosphine oxides, and one compound was found to be more reactive in photopolymerization than the commercial photoinitiator TPO-L for an irradiation at 395 nm.
Recent Advances in Synthesis of Benzothiazole Compounds Related to Green Chemistry
Authors: Gao Xiang , Liu Jiao , Zuo Xin , Feng Xinyue , Gao Ying
Published: April 2020

Benzothiazoles have played an important role in the field of biochemistry and medicinal chemistry due to their highly pharmaceutical and biological activity. The development of synthetic processes is undoubtedly one of the most significant problems facing researchers. In this review paper, we provided recent advances in the synthesis of benzothiazole compounds related to green chemistry from condensation of 2-aminobenzenethiol with aldehydes/ketones/acids/acyl chlorides and the cyclization of thioamide or carbon dioxide (CO2) as raw materials, and the future development trend and prospect of the synthesis of benzothiazoles were anticipated.
Polymeric Coatings Based on Water-Soluble Trimethylammonium Copolymers for Antifouling Applications
Authors: Tsagdi Artemis , Druvari Denisa , Panagiotaras Dionisios , Avramidis Pavlos , Bekiari Vlasoula , Kallitsis Joannis K.
Published: April 2020

Crosslinked polymeric materials based on a quaternary trimethylammonium compound were developed and evaluated as potential antifouling coatings. For this purpose, two water-soluble random copolymers, poly(4-vinylbenzyltrimethylammonium chloride-co-acrylic acid) P(VBCTMAM-co-AAx) and poly(N,N-dimethylacrylamide-co-glycidylmethacrylate) P(DMAm-co-GMAx), were synthesized via free radical polymerization. A water based approach for the synthesis of P(VBCTMAM-co-AAx) copolymer was used. Coatings of the complementary reactive copolymers in different compositions were obtained by curing at 120 °C for one day and were used to coat aquaculture nets. These nets were evaluated in respect to their release rate using Total Organic Carbon (TOC) and Total Nitrogen (TN) measurements. Finally, the antifouling efficacy of these newly-composed durable coatings was investigated for 14 days in accelerated conditions. The results showed that this novel polymeric material provides contact-killing antifouling activity for a short time period, whereas it functions efficiently in biofouling removal after high-pressure cleaning.
Synthesis and Biological Evaluation of New Antitubulin Agents Containing 2-(3′,4′,5′-trimethoxyanilino)-3,6-disubstituted-4,5,6,7-tetrahydrothieno[2,3-c]pyridine Scaffold
Authors: Romagnoli Romeo , Prencipe Filippo , Oliva Paola , Cacciari Barbara , Balzarini Jan , Liekens Sandra , Hamel Ernest , Brancale Andrea , Ferla Salvatore , Manfredini Stefano , Zurlo Matteo , Finotti Alessia , Gambari Roberto
Published: April 2020

Two novel series of compounds based on the 4,5,6,7-tetrahydrothieno[2,3-c]pyridine and 4,5,6,7-tetrahydrobenzo[b]thiophene molecular skeleton, characterized by the presence of a 3′,4′,5′-trimethoxyanilino moiety and a cyano or an alkoxycarbonyl group at its 2- or 3-position, respectively, were designed, synthesized, and evaluated for antiproliferative activity on a panel of cancer cell lines and for selected highly active compounds, inhibition of tubulin polymerization, and cell cycle effects. We have identified the 2-(3′,4′,5′-trimethoxyanilino)-3-cyano-6-methoxycarbonyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine derivative 3a and its 6-ethoxycarbonyl homologue 3b as new antiproliferative agents that inhibit cancer cell growth with IC50 values ranging from 1.1 to 4.7 μM against a panel of three cancer cell lines. Their interaction with tubulin at micromolar levels leads to the accumulation of cells in the G2/M phase of the cell cycle and to an apoptotic cell death. The cell apoptosis study found that compounds 3a and 3b were very effective in the induction of apoptosis in a dose-dependent manner. These two derivatives did not induce cell death in normal human peripheral blood mononuclear cells, suggesting that they may be selective against cancer cells. Molecular docking studies confirmed that the inhibitory activity of these molecules on tubulin polymerization derived from binding to the colchicine site.
Relationship of Performance Measures and Muscle Activity between a 180° Change of Direction Task and Different Countermovement Jumps
Authors: Nygaard Falch Hallvard , Guldteig Rædergård Håvard , Van den Tillaar Roland
Published: April 2020

The ability to rapidly perform change of direction (COD) is crucial for performance in Soccer. COD speed is thought to share similarities with countermovement jumps in kinematics and muscle activation. Thus, the objective of the current study was to investigate the relationship between muscle activities in performance measures of a modified 505-agility test and different countermovement jumps. Twenty-one experienced soccer players performed a COD test including the 505-agility test and uni- and bi-lateral horizontal and vertical countermovement jumps. The main findings were that the vertical bilateral and horizontal unilateral countermovement jump were able to predict total time to complete the COD, but not 505-agility time. Muscle activity in the COD and countermovement jumps was only distinguished by a higher peak muscle activity for the adductor longus, semitendinosus and biceps femoris in the COD to stabilize the hip and decelerate knee joint movements when turning compared with the jumps. Conclusively, the relationship between performance in countermovement jumps and total time to complete the COD test was due to longer sprint distances, which makes the distinction between performances bigger. Peak muscle activity of most muscles is similar between the jumps and the COD step, indicating similar muscular demands between these activities.
Systematic Mapping of Research on Farm-Level Sustainability in Egg and Chicken Meat Production
Authors: Gunnarsson Stefan , Arvidsson Segerkvist Katarina , Göransson Lina , Hansson Helena , Sonesson Ulf
Published: April 2020

The sustainability of future poultry production needs to be improved in order to meet global challenges. The global chicken population has expanded significantly in recent decades, due to increased human demand for eggs and chicken meat. Therefore, it is critically important to mitigate challenges to the sustainability of modern poultry production, such as pollution, the depletion of finite natural resources and animal welfare issues. This study systematically mapped the scientific literature on farm-level sustainability in egg and chicken meat production. The concept of sustainability was considered holistically, covering its economic, environmental and social dimensions, each consisting of a broad range of different aspects that may contradict or reinforce each other. The literature published between January 2000 and March 2020 with a geographical focus on Europe, North America and Australia–New Zealand, were included. The literature search resulted in a total of 428 hits, but after the exclusion of articles that did not match the scope of the study, only 26 papers remained for the systematic mapping. Of these, only three papers covered all three dimensions of sustainability. Aspects of economic sustainability were addressed in 10 papers, aspects of environmental sustainability in 18 papers, and aspects of social sustainability in 23 papers. The findings in this study are an important foundation for the discussion and prioritisation of future actions to increase knowledge of farm-level sustainability in egg and chicken meat production.
Euler–Catalan’s Number Triangle and Its Application
Authors: Shablya Yuriy , Kruchinin Dmitry
Published: April 2020

In this paper, we study such combinatorial objects as labeled binary trees of size n with m ascents on the left branch and labeled Dyck n-paths with m ascents on return steps. For these combinatorial objects, we present the relation of the generated number triangle to Catalan’s and Euler’s triangles. On the basis of properties of Catalan’s and Euler’s triangles, we obtain an explicit formula that counts the total number of such combinatorial objects and a bivariate generating function. Combining the properties of these two number triangles allows us to obtain different combinatorial objects that may have a symmetry, for example, in their form or in their formulas.
Clinical and Epidemiological Characteristics of Severe Acute Adult Poisoning Cases in Martinique: Implicated Toxic Exposures and Their Outcomes
Authors: Resiere Dabor , Kallel Hatem , Oxybel Odile , Chabartier Cyrille , Florentin Jonathan , Brouste Yannick , Gueye Papa , Megarbane Bruno , Mehdaoui Hossein
Published: April 2020

The epidemiology of severe acute poisonings in the French overseas departments of the Americas remains poorly reported. The main objective of this study was to determine the epidemiology and characteristics of severe acutely poisoned adult patients. Methods: A retrospective descriptive study was conducted from 1 January 2000 to 31 December 2010 in severely poisoned patients presenting to the emergency department (ED) of the University Hospital of Martinique, and the general public hospitals of Lamentin and Trinité. Results: During the study period, 291 patients were admitted for severe poisoning, giving an incidence rate of 7.7 severe cases/100,000 inhabitants. The mean age was 46 ± 19 years and 166 (57%) were male. Psychiatric disorders were recorded in 143 (49.8%) patients. Simplified Acute Psychological Score (SAPS II) at admission was 39 ± 23 points and Poisoning Severity Score (PSS) was 2.7 ± 0.8 points. Death was recorded in 30 (10.3%) patients and hospital length of stay was 6 ± 7 days. The mode of intoxication was intentional self-poisoning in 87% of cases and drug overdose was recorded in 13% of cases. The toxic agent involved was a therapeutic drug in 58% and a chemical product in 52% of cases. The predominant clinical manifestations were respiratory failure (59%), hemodynamic failure (27%), neurologic failure (45%), gastrointestinal manifestations (27%), and renal failure (11%). Polypnea, shock, ventricular fibrillation or tachycardia, and gastro-intestinal disorders were the main symptoms associated with death. The main biological abnormalities associated with death in our patients were metabolic acidosis, hypokalemia, hyperlactatemia, hypocalcemia, renal injury, rhabdomyolysis, increased aspartate aminotransferases, and thrombocytopenia. Extracorporal membrane oxygenation (ECMO) was used in three patients and specific antidotes were used in 21% of patients. Conclusions: Acute poisonings remain a major public health problem in Martinique with different epidemiological characteristics to those in mainland France, with a high incidence of poisoning by rural and household toxins.
Case study: Effect of acoustic characteristics of interior aircraft noise on pilot
Authors: Asakura T. , Takagi Y.
Published: April 2020

The influence of acoustic characteristics of in-flight noise on airplane operations and sound impression has been investigated through objective and subjective measure including the flight simulation. The authors verified the influence of the noise conditions including seven conditions,
in which the sound pressure levels and frequency characteristics of them were parametrically changed, on the airplane operations using shortterm flight simulation. Resultantly, the change of the sound pressure levels of the in-flight noise did not greatly affect the operation accuracy although
clearly affected the subjective impressions. On the other hand, it has been suggested that the change of the frequency characteristics of in-flight noise affected not only the subjective impressions but also the operation accuracy.
Case study: Theoretical calculation model and variable condition analysis research on the water-splashing noise for natural draft wet cooling towers
Authors: Zhouo Yang , Gao Ming , He Suoying , Shi Yuetao , Sun Fengzhong
Published: April 2020

Based on the basic theory of water droplets impact noise, the generation mechanism and calculation model of the water-splashing noise for natural draft wet cooling towers were established in this study, and then by means of the custom software, the water-splashing noise was studied
under different water droplet diameters and water-spraying densities as well as partition water distribution patterns conditions. Comparedwith the water-splashing noise of the field test, the average difference of the theoretical and the measured value is 0.82 dB, which validates the accuracy
of the established theoretical model. The results based on theoretical model showed that, when the water droplet diameters are smaller in cooling tower, the attenuation of total sound pressure level of the water-splashing noise is greater. From 0 m to 8 m away from the cooling tower, the sound
pressure level of the watersplashing noise of 3 mm and 6 mm water droplets decreases by 8.20 dB and 4.36 dB, respectively. Additionally, when the water-spraying density becomes twice of the designed value, the sound pressure level of water-splashing noise all increases by 3.01 dB for the cooling
towers of 300 MW, 600 MW and 1000 MW units. Finally, under the partition water distribution patterns, the change of the sound pressure level is small. For the R s/2 and Rs/3 partition radius (Rs is the radius of water-spraying area), when the water-spraying density ratio between the outer
and inner zone increases from 1 to 3, the sound pressure level of water-splashing noise increases by 0.7 dB and 0.3 dB, respectively.
Study on noise characteristics of a novel equal-thickness screen
Authors: Wen Pengfei , Duan Chenlong , Tang Ligang , Qiao Jinpeng , Jiang Haishen , Wu Jida
Published: April 2020

As the key unit in coal preparation and utilization, equal-thickness screens characterized by a large capacity and high efficiency have been extensively applied in coal preparation plants. Recently, the noise pollution caused by the screening of coal has become more and more serious.
Reducing the noise of vibrating screens is the key to control the noise of coal preparation plants. In this article, the noise test system was used to measure three-dimensional (3D) sound intensity of the equal-thickness screen. According to the analysis of sound intensity distribution and
spectral coherence, the main sources of noise were identified. The main sources of noise of equal-thickness screen were vibration motors, side panel, screen surface and damping supports. A displacement model was fitted to the experimental data, and the kinematics of the sieve body was studied.
The results showed that the amplitude of the sieve body decreased as the distance from the feeding end (towards the discharge end). Similarly, the intensity of the noise decreased about 2 dB in the same direction (from the feeding end to discharge end). However, in the direction perpendicular
to the movement of the material, the noise distribution was symmetrical. Finally, various noise reduction measures were also put forth. It could be seen that when the composite spring was adopted as the damping support and the structures of vibration motors, screen surface and side panel were
changed, the noise could be effectively reduced.
Acute exercise on memory function: open vs. closed skilled exercise
Authors: Cantrelle Justin , Burnett Grace , Loprinzi Paul D.
Published: April 2020

Background:Previous studies suggest that acute exercise may improve memory function. Few studies, however, have investigated the differential effect of the acute exercise movement patterns on memory. Such an effect is plausible, as research demonstrates that open-skilled exercise (e.g.,racquetball) may have a greater effect on memory-related neurotrophins (e.g., brain-derived neurotrophic factors) when compared to closed-skilled exercise (e.g. treadmill exercise). A key distinction between open- and closed-skilled exercise is that open-skilled exercises are those that require an individual to react in a dynamic way to a changing, unpredictable environment. Our aim in this study was to assess wether retrospective and prospective memory are differentially influenced from open- and closed-skilled acute exercise.Methods:A within-subject design was employed. Participants (Mage= 20.6 years; 69% female)completed two visits, in a counterbalanced order. The two experimental conditions included open-skilled acute exercise (racquetball) and closed-skilled acute exercise (treadmill exercise),each lasting 30-minute at 60% of heart rate reserve (HRR). During both experimental conditions,participants completed short- and long-term assessments of retrospective and prospective memory function. Retrospective memory was evaluated across multiple word-list trials (e.g.,Trials 1-6, 20-minute delay, 24-hour delay).Results:No significant effect of exercise was found on prospective memory. For retrospective memory, there was a significant main effect for condition, F(1, 57) = 5.33, P = 0.02, η2= 0.004,main effect for trial, F(4.12, 234.9) = 227.85,P< 0.001, η2= 0.46, but no condition by trial interaction, F(4.63, 264.08) = 1.022,P= 0.40, η2= 0.002.Conclusion:Retrospective memory was greater after closed-skilled exercise (treadmill) when compared to open-skilled exercise (racquetball).
A cross-sectional study to investigate motivation for physical activity in a sample of Iranian community-dwelling older adults
Authors: Derakhshanrad Seyed Alireza , Piven Emily , Zeynalzadeh Ghoochani Bahareh
Published: April 2020

Background: On the basis of the Social-Ecological Model, there are assumed to be three sources of motivation – intrapersonal, interpersonal, and community motivation – that prompt older adults to participate in physical activity (PA). These three motivational sources can lead to PA behavior adherence. Little empirical research exists that investigates which motivational source is more influential in older adults’ adherence to PA, thus creating an area of interest for this research. Methods: A cross-sectional study was used to investigate the relationship between levels of PA and different sources of motivation. The convenience sample of 140 community-dwelling older adults, aged 60 and greater, living in Shiraz, Iran agreed to complete self-reported questionnaires,to measure motivation and PA. Five statistical tests were used: Independent-samples t test, one way ANOVA, Pearson correlation coefficient, chi-square, and ordinal regression. Results: Ordinal regression indicated that gender (P = 0.001, CI: 0.523-2.115) and intrapersonal motivation (P < 0.001, CI: 0.038-0.126) were useful predictors of variations in the levels of PA. Compared to males, females engaged in PA with less frequency (P = 0.006). Community motivation decreased with age (r = - 0.213, P < 0.05). There were no significant relationships between age, educational level, health status, and PA (P > 0.05). Conclusion: Interpersonal and community motivation were insignificant factors for PA participation, perhaps due to non-facilitating environment. Future research should be conducted to investigate the environmental issues that hinder PA participation in older adults.
What are the optimal cut-off points of anthropometric indices for prediction of overweight and obesity? Predictive validity of waist circumference, waist-to-hip and waist-to-height ratios
Authors: Tutunchi Helda , Ebrahimi-Mameghani Mehrangiz , Ostadrahimi Alireza , Asghari-Jafarabadi Mohammad
Published: April 2020

Background: Planning for obesity prevention is an important global health priority. Our aim in this study was to find the optimal cut-off points of waist circumference (WC), waist- to- hipratio (WHR) and waist- to- height ratio (WHtR), as three anthropometric indices, for prediction of overweight and obesity. We also aimed to compare the predictive ability of these indices to introduce the best choice. Methods: In this cross-sectional study, a total of 500 subjects were investigated. Anthropometric indicators were measured using a standard protocol. We considered body mass index (BMI) as the simple and most commonly used index for measuring general obesity as the comparison indicator in the present study to assess the diagnostic value for other reported obesity indices.We also performed receiver operating characteristic (ROC) curve analysis to define the optimal cut-off points of the anthropometric indicators and the best indices for overweight and obesity. Results: The proposed optimal cut-offs for WC, WHtR, and WHR were 84 cm, 0.48 and 0.78for women and 98 cm, 0.56 and 0.87 for men, respectively. The area under the ROC curve ofWHtR (women: AUC=0.97, 95% CI: 0.96-0.99 vs. men: AUC=0.97, 95%CI: 0.96-0.99) and WC(women: AUC=0.97, 95% CI, 0.95-0.99 vs. men: AUC=0.98, 95% CI: 0.97-0.99) were greater than WHR (women: AUC=0.79, 95% CI =0.74-0.85 vs. men: AUC=0.84, 95% CI=0.79-0.88). Conclusion: This study demonstrated that the WC and WHtR indicators are stronger indicators compared to the others. However, further studies using desirable and also local cutoffs against more accurate techniques for body fat measurement such as computerized tumor (CT) scans and dual-energy x-ray absorptiometry (DEXA) are required.
Clostridium difficile in patients with nosocomial diarrhea, Northwest of Iran
Authors: Hematyar Yalda , Pirzadeh Tahereh , Moaddab Seyyed Reza , Ahangarzadeh Rezaee Mohammad , Memar Mohammad Yousef , Samadi Kafil Hossein
Published: April 2020

Background:
Clostridium difficile is known as a prevalent pathogen leading to infections ranging from mild diarrhea to severe disease and death. The aim of the present study was to evaluate the incidence of C. difficile from inpatients with nosocomial diarrhea hospitalized in different wards in the northwest region of Iran. Methods: In this cross-sectional study, 485 diarrheal stool samples were collected from 384 patients referred from different wards of Imam Reza, Sina and Pediatric hospitals, Tabriz and transferred to the laboratory from 25 March 2015 till 1 March 2018. Immuno-chromatographicassay for detection of toxins A and B of C. difficile was used for identification. Results: Clostridium difficile was isolated from 24 (4.7%) out of 485 samples. Fifteen patients(62.5%) were males and 9 were females (37.5%). Twelve positive patients were from the gastrointestinal ward (50%), 5 patients (20.8%) from surgery ward, 3 patients from infectious disease ward (12.5%), 3 patients from rheumatology ward (12.5%) and 1 patient (4.1%) were collected from neurology ward. 95.3% of diarrhea samples had no signs from toxin A and B. Conclusion: These results indicate most of infected patients were from the gastrointestinaland surgery wards which show a different pattern of infection compared to previous studies.The neurology department had the lowest rate of infection. C. difficile is a health threat afterantibiotic consumption and for health promotion, developing strategies for less antibioticconsumption and preventing these emerging infections is critical. The low rate of this infection shows improvement in knowledge and effect of stewardships in physicians.
The association of maternal plant-based diets and the growth of breastfed infants
Authors: Daneshzad Elnaz , Moradi Maedeh , Maracy Mohammad R , Brett Neil R. , Bellissimo Nick , Azadbakht Leila
Published: April 2020

Background:Studies are needed to further understand how different plant-based dietary patterns of mothers relate to infant growth. Thus, we investigated the association between maternal plant-based diets and infant growth in breastfed infants during the first 4 months of life.Methods:This cross-sectional study included 290 Iranian mothers and infants. Maternal dietary intake was assessed using a 168-question validated semi-quantitative food frequency questionnaire (FFQ). Three plant-based diet indices (PDIs) were then created to evaluate dietary intakes. Eighteen food groups were classified in three main categories by scoring method: wholeplant diet, healthy plant diet, and animal and unhealthy plant diet.Results:Participants in the top tertile of unhealthy PDI (uPDI) had a lower intake of potassium,phosphorus, zinc, magnesium, calcium, folate and vitamin C, B1, B2, and B3. The upper tertileof uPDI was associated with stunting at 4-month in infants (uPDI: odds ratio [OR] = 3.27, 95%CI= 1.32, 8.10). There were no significant associations between plant-based diet scores and anthropometric indices, including weight, weight status and head circumference (P> 0.05).Conclusion:In conclusion, higher adherence to uPDI may be associated with stuntingamong Iranian infants. Other PDIs were not associated with anthropometric measures. Future studies are needed to further understand the association between plant-based diets and infant growth.
USING MIND MAPS IN TEACHING ENGLISH GRAMMAR TO GRADE-10 STUDENTS
Authors: Yến Trần Thị
Published: April 2020

Giáo viên ngoại ngữ đã sử dụng sơ đồ tư duy để khuyến khích học sinh học từ vựng. Mục đích của nghiên cứu này là điều tra tính hiệu quả của việc sử dụng sơ đồ tư duy trong việc dạy và học ngữ pháp của học sinh lớp 10. Đối tượng nghiên cứu bao gồm 20 học sinh lớp 10 trường THPT Chuyên Thái Nguyên, được chia thành hai nhóm (thực nghiệm và đối chứng). Nghiên cứu được thực hiện dựa trên các phương pháp thực nghiệm, định tính và định lượng. Trước hết, một thực nghiệm đã được tiến hành để kiểm tra tác động của sơ đồ tư duy đối với trình độ ngữ pháp của học sinh lớp 10. Kết quả thực nghiệm cho thấy có sự khác biệt không nhỏ trong điểm trung bình của nhóm thực nghiệm và nhóm đối chứng trong bài kiểm tra ngữ pháp vì việc sử dụng sơ đồ tư duy trong việc dạy và học ngữ pháp đã có tác động tích cực lên nhóm thực nghiệm. Cùng với thực nghiệm, việc quan sát lớp học cũng được thực hiện để thu thập dữ liệu liên quan đến phản hồi và thái độ của học sinh trong các bài học ngữ pháp. Cuối cùng, bảng hỏi được sử dụng trước và sau thực nghiệm nhằm thu thập khó khăn liên quan đến việc học ngữ pháp cũng như phản hồi của người học đối với việc sử dụng sơ đồ tư duy trong các lớp học ngữ pháp. Dựa trên kết quả điều tra, nghiên cứu đã đưa ra những gợi ý giúp học sinh và giáo viên sử dụng sơ đồ tư duy trong học tập và giảng dạy ngữ pháp một cách hiệu quả.
THE EFFECTIVENESS OF USING VISUAL AIDS TO PROMOTE SPEAKING SKILLS FOR THE 12TH GRADERS AT CAM PHA HIGH SCHOOL
Authors: Nhung Nguyễn Thị , Dương Nguyễn Thị
Published: April 2020

Nghiên cứu này là một nỗ lực để điều tra việc sử dụng các phương tiện trực quan trong việc dạy nói cho  học sinh lớp 12 tại trường trung học Cam Pha. Mục đích chính của nghiên cứu là tìm hiểu: tình hình dạy và học nói tiếng Anh hiện nay tại trường trung học Cam Pha; các hoạt động và kỹ thuật giảng dạy với các phương tiện trực quan được giáo viên và học sinh áp dụng theo sở thích; những khó khăn trong việc học và dạy nói tiếng Anh và sau đó đưa ra một số gợi ý cho giáo viên để kích thích học sinh nói và vượt qua những khó khăn mà họ phải đối mặt trong việc dạy nói tiếng Anh cho học sinh. Nghiên cứu áp dụng phương pháp nghiên cứu hành động, với việc sử dụng các phương pháp nghiên cứu hỗn hợp liên quan đến cả dữ liệu định tính và định lượng. Hai trăm học sinh lớp 12 và bốn giáo viên đã tham gia vào nghiên cứu. Các phát hiện cho thấy rằng việc sử dụng các phương tiện trực quan giúp học sinh tăng cường đáng kể sự quan tâm và tham gia vào các kỹ năng nói. Học sinh cũng báo cáo sự cải thiện của họ về các khía cạnh khác nhau của kỹ năng nói. Nghiên cứu đề xuất ý nghĩa và đề xuất sử dụng các phương tiện trực quan trong việc cải thiện kỹ năng nói.
PARADA CARDÍACA: PRINCIPAIS COMPLICAÇÕES OCASIONADAS PELA SÍNDROME DA RABDOMIÓLISE
Authors: dos Santos Araujo Amauri , Nunes da Silva Izadora , dos Santos Silva Glaucia , Maria do Nascimento Vanessa
Published: April 2020

A parada cardiorrespiratória (PCR) é uma situação clínica que acarreta prioridade de atendimento devido à necessidade de intervenções rápidas e eficazes. OBJETIVO: identificação da produção científica a nível internacional e nacional sobre as principais complicações fisiopatológicas advindas da síndrome rabdomiólise, MÉTODOS: trata-se de um estudo de revisão integrativa, realizada na bases de dados Biblioteca Virtual em Saúde (BVS), da Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS), Base de Dados em Enfermagem (BDENF), Scientific Eletronic Library Online (SciELO) e Medical Literature Analysisand Retrieval System Online (MEDLINE). RESULTADOS E DISCUSSÃO: O presente estudo possibilitou compreender e identificar a definição da condição patológica e sua ampla vertente e etiologia. Entretanto, além da sua relevância, identificou-se a limitação de conhecimento pelos profissionais da saúde, oriundo da escassez de estudo publicado na área. CONCLUSÃO: A falta de conhecimento pode causar algumas situações que interferem na atuação de toda a equipe na assistência prestada. É conferido ao enfermeiro a responsabilidade do suprimento do carrinho de parada e todos os materiais necessários, bem como os cuidados dispensados durante todo o evento. Palavras chave: Lesão muscular. Parada Cardíaca. Rabdomiólise.