bluuebunny/crossref_metadata_2025 huggingface dataset:
«НОВА КАМЕРНІСТЬ» ІНСТРУМЕНТАЛЬНОЇ МУЗИКИ ХХ СТОЛІТТЯ ТА ЇЇ ВПРОВАДЖЕННЯ У СОНАТІ ДЛЯ СКРИПКИ ТА ФОРТЕПІАНО Ф. ПУЛЕНКА
Authors: Humen O. I. , Vizun T. O.
Published: January 2020

Мета статті – виявити особливості камерно-інструментальної музики Ф. Пуленка в аспекті «нової камерності» ХХ сторіччя. Відповідно до поставленої мети визначено наступні завдання наукового дослідження, а саме – висвітлити особливі риси французької камерної музики ХХ століття, продемонструвати недостатність вивчення камерно-інструментальної музики французького майстра у вітчизняному музикознавстві, виявити обумовленість стильових особливостей камерно-інструментальної музики Ф. Пуленка з музикою «Шістки», описати особливості трактування жанру сонати у творчості композитора, а також висвітлити історію створення сонати для скрипки і фортепіано Ф. Пуленка та її приховану програмність. Ціллю пропонованої наукової розвідки є також і аналіз окресленої сонати з точки зору множинності тематизму та домінування художньо-музичної процесуальності. Методологія означеного дослідження ґрунтується як на загально-наукових, так і спеціальних методах, а саме – на історичному, компаративному, жанрово-стильовому та структурно-функціональному. Наукова новизна статті полягає у наступному. Скрипкову сонату Ф. Пуленка розглянуто з позицій явища «нової камерності», що надає змогу виявити стильові версії французької камерної музики ХХ століття. Висновки. На прикладі сонати для скрипки та фортепіано Ф. Пуленка виявлено риси «нової камерності» у французькій музиці ХХ століття, а саме – ігрова та театральна природа жанрів, відносна вільність форми, узагальнена портретність. Множинний та різноманітний тематизм сонати можливо трактувати як віддзеркалення вражень від складного, експресивного та трагічного образу Лорки. Домінування процесуальності над кристалічною формою надає сонаті динамічності та мобільності, притаманній музиці ХХ століття. Все це дозволяє бачити у феномені «нової камерності» передусім дух експерименту та невпинного пошуку нових шляхів розвитку інструментального ансамблю.
¿Se puede ser realista en torno a las leyes de la termodinámica?
Authors: Rojas Durán Edgar Eduardo
Published: January 2020

En el estudio de las teorías filosóficas sobre las leyes naturales, se ha prestado poca atención a las leyes de la termodinámica. El artículo busca aplicar los marcos conceptuales de tres teorías relevantes, la universalista, la disposicionalista y la contrafactualista, para reformular dichas leyes, y mostrar cómo los marcos conceptuales de las dos primeras no resultan adecuados para tal reformulación, pero sí lo es el de la tercera. Si esta teoría se considera realista, se puede ser realista en este caso.
Bal kamrai deformáció cardialis könnyűlánc-amyloidosisban és hypereosinophilia-szindrómában. Eredmények a MAGYAR-Path Tanulmányból
Authors: Kormányos Árpád , Domsik Péter , Kalapos Anita , Marton Imelda , Földeák Dóra , Modok Szabolcs , Gyenes Nándor , Borbényi Zita , Nemes Attila
Published: January 2020

Absztrakt:

Bevezetés: A hypereosinophilia-szindróma (HES) és az
immunglobulinkönnyűlánc-amyloidosis (ALA) két ritka hematológiai betegség,
melyek cardialis eltérésekkel járnak együtt. Célkitűzés: A
jelen vizsgálat célja a HES- és ALA-betegek bal kamrai (BK-i) deformációs
paramétereinek összehasonlító vizsgálata volt háromdimenziós speckle-tracking
echokardiográfia (3DSTE) segítségével. Módszer: A vizsgálatok
során 10 HES-beteg (átlagos életkor: 60,9 ± 14,7 év) és 19 ALA-ban szenvedő
páciens (átlagos életkor: 63,4 ± 7,8 év, 13 férfi) eredményeit elemeztük.
Kontrollcsoportként 13, korban és nemben egyeztetett, egészséges felnőtt
szolgált (átlagos életkor: 59,2 ± 4,3 év, 5 férfi). Valamennyi esetben teljes
körű kétdimenziós Doppler-echokardiográfiás vizsgálat készült 3DSTE-vel
kiegészítve. Eredmények: A kontrollcsoporthoz képest az
ALA-betegcsoportban mért valamennyi basalis szegmentális BK-i strain
szignifikánsan alacsonyabbnak mutatkozott. Az ALA-betegek globális és átlagolt
szegmentális BK-i longitudinális strain (LS) értékei az egészséges
kontrollcsoporthoz hasonlítva szignifikánsan alacsonyabbnak bizonyultak. A
HES-betegcsoport és az egészséges kontrollok összehasonlítása során szignifikáns
különbséget tapasztaltunk a globális BK-LS tekintetében, míg a szegmentális
basalis BK-LS is szignifikánsan alacsonyabbnak bizonyult a HES-betegekben. A
HES- és az ALA-betegcsoport értékeit összehasonlítva a basalis BK-i radiális és
3D strain mutatott szignifikáns eltérést. Következtetések: A
3DSTE alkalmas módszer a HES- és az ALA-betegcsoportban a BK-i deformációs
mechanika részletes vizsgálatára. Mindkét betegcsoportban jelentős deformációs
eltérések tapasztalhatók, ALA fennállása esetén az eltérések kifejezettebbek.
Orv Hetil. 2020; 161(5): 169–176.
Koraszülöttek kétéves kori pszichomotoros fejlettsége a leggyakoribb krónikus utóbetegségek tekintetében
Authors: Kenyhercz Flóra , Sveda Brigitta , Nagy Beáta Erika
Published: January 2020

Absztrakt:

Bevezetés: A neonatológia fejlődésével a koraszülöttek életben
tarthatóságának határai kitolódtak, így nőtt az utóbetegségekkel túlélők aránya.
A koraszülöttek későbbi életminőségét, életkilátásait és szociális integrációját
leginkább befolyásoló kórképek a retinopathia prematurorum (ROP), az
intraventricularis haemorrhagia (IVH) és a bronchopulmonalis dysplasia (BPD).
Célkitűzés: A 2500 gramm alatti születési súlyú (LBW)
kisgyermekek kétéves kori pszichomotoros fejlődésének leírása a leggyakoribb
utóbetegségek (ROP, IVH, BPD) tekintetében. Módszer: Vizsgálati
mintánkat 200 LBW-kisgyermek alkotta kétéves korban. A pszichomotoros
készségeket a Brunet–Lézine-féle fejlődési skálával mértük fel, valamint az
újszülöttkori zárójelentéseket elemeztük retrospektív módon.
Eredmények: A születési súly az életkori korrekciót
követően is pozitívan korrelált a kétéves kori fejlődési kvócienssel (FQ), míg a
kórházi tartózkodás hossza negatívan. Az utóbetegségek közül az I/II. stádiumú
újszülöttkori IVH nem, a III/IV. stádiumú azonban szignifikáns előrejelzőnek
bizonyult az alacsonyabb FQ tekintetében. Hasonló összefüggést találtunk a ROP
stádiumaival is, az enyhe fokú nem, a III/IV-es azonban szignifikánsan
befolyásolta a kétéves kori pszichomotoros fejlettségi szintet. A BPD-nek nem
találtuk jelentős összefüggését az FQ-val. A szignifikánsnak talált kórképek
homogenitásvizsgálata azt mutatta, hogy egymástól független hatásokról
beszélhetünk. Alátámasztottuk továbbá azon összefüggést, miszerint egy
koraszülött minél több betegségben szenved, annál veszélyeztetettebb a későbbi
fejlődési elmaradás tekintetében. Következtetés: Ajánljuk az
1500 gramm alatti születési súlyú gyermekek körében a fejlődésük szempontjából
leginkább veszélyeztetettek – mint az újszülöttkori súlyos ROP-on és IVH-n
átesettek – minél korábbi életszakaszban történő korai fejlesztését az esetleges
képességdeficitek csökkentése érdekében és fejlődésük utánkövetését, így
megelőzve későbbi mentális, motoros nehézségeket. Orv Hetil. 2020; 161(5):
183–192.
A musculus tensor tympani és a musculus stapedius ín átvágásának hatása a Ménière-betegségben szenvedők életminőségére
Authors: Szirmai Ágnes , Maihoub Stefani , Molnár András , Fent Zoltán , Tamás László , Polony Gábor
Published: January 2020

Absztrakt:

Bevezetés: A musculus (m.) stapedius és a m. tensor tympani (TT)
inának átvágása egy minimálinvazív sebészi lehetőség a Ménière-betegség sebészi
terápiájában. A feltételezett hatásmechanizmus szerint a tensor tympani
medializálja a stapest az ovális ablakban, és ennek, valamint a stapediusínnak
az átvágása befolyásolja a belső fül nyomásviszonyait Ménière-betegségben.
Célkitűzés: Dizziness Handicap Inventory (DHI) –
szédülésterheltségi skála – és Tinnitus Handicap Inventory (THI) –
fülzúgásterheltségi skála – segítségével annak megállapítása, hogy a tenotomia
hogyan befolyásolja a Ménière-betegek életminőségét. Módszer:
Diagnosztizált, egyoldali Ménière-betegeket vizsgáltunk (22 beteg), akik
előzetes beleegyezésük után tenotomia műtéten estek át, általános vagy helyi
érzéstelenítésben. A betegek a műtét előtt, a műtét után 3 hónappal és egy évvel
töltöttek ki kérdőívet, és beszámoltak betegségük tüneteiről.
Statisztikai analízis: A statisztikai analízis az IBM SPSS
V24-es programmal készült. Mivel a vizsgált paraméterek nem mutattak
normáleloszlást, nemparametrikus tesztet (Mann–Whitney-féle U-teszt)
alkalmaztunk. Szignifikanciaszintnek minden esetben a p<0,05 értéket
tekintettük. Eredmények: A DHI-értékek minden betegben
szignifikánsan csökkentek, azaz életminőségük jelentősen javult. Elmondásuk
szerint szédüléses rohamaik ritkábbá váltak, rövidültek. A fülzúgás
szignifikánsan csökkent. Minden beteg állapotjavulásról számolt be.
Következtetés: Bár a műtét hatásának patomechanizmusa (a
stapes medializációjának csökkenése az ovális ablakban) nem teljesen tisztázott,
és az utánkövetési idő sem hosszú, a rohamok súlyosságának csökkentésével a
tenotomia ígéretes, minimálinvazív sebészi lehetőségnek tűnik a konzervatív
terápiára rezisztens, Ménière-betegségben szenvedő betegek életminőségének
javításában. Orv Hetil. 2020; 161(5): 177–182.
A fizikai aktivitás hatásai az időskori kognitív működésre
Authors: Mile Marianna , Tatai Csilla , Fábián Balázs , Csiki Zoltán
Published: January 2020

Absztrakt:

Az időskorú személyek száma és társadalmi aránya folyamatosan növekszik, különös
tekintettel az európai országokra, de ez a világ teljes népességére is
vonatkozik. Az idősebb korosztály arányának további gyarapodásával az öregedő
társadalom egészségi állapotának romlása okozta szociális és egészségügyi
szférákat érintő többletköltségek is egyre tovább emelkednek. Az öregedés
folyamata az egészségi állapot romlásának és az általános funkcióképesség
csökkenésének testi vonatkozásain túl a mentális, kognitív teljesítmény
romlásával is együtt jár, ami tovább nehezíti az idős korosztály mindennapjait.
Ezek a tények felhívják a figyelmet a beavatkozás megjósolható szükségességére.
A korábbi vizsgálati eredmények szerint a fizikai aktivitás alkalmas lehet a
kognitív működés javítására, a romlás megállítására és megelőzésére. A jelen
közleményben áttekintjük a fizikai aktivitásnak a kognitív működésre kifejtett
hatásait mind általánosságban, mind pedig három specifikus mozgásforma
tekintetében, illetve a további aktuális kutatási irányokat is felvázoljuk. Orv
Hetil. 2020; 161(5): 163–168.
Extrém hosszú tartamú 1-es típusú diabetes mellitus ritka esete
Authors: Fövényi József
Published: January 2020

Absztrakt:

Az 1-es típusú diabetes mortalitása, bár csökkenő tendenciát mutatva, jelentősen
meghaladja a standard mortalitást. Ez egyúttal a diabetesszel megélt életévek
rövidülésével jár együtt. Az esetismertetés tárgya egy 86 éves diabetestartammal
a 91. életévét megélő nőbeteg, akit több mint 55 éven keresztül egyetlen orvos –
a szerző – kezelt/gondozott. Az 1932-ben, ötéves korában fellépett diabetest
először naponta háromszor adagolt gyors hatású inzulinnal, majd 1940-től kezdve
naponta egyszer alkalmazott gyors hatású és cink-protamin inzulinnal, később
sertés, majd humán kristályos cinkinzulinnal, majd az utolsó 16 évben gyors
hatású NPH-inzulin keverékével kezelték. Ennek oka az volt, hogy a beteg
rögeszmésen ragaszkodott a napi egyszeri inzulinadáshoz, és hogy esetében
mindegyik inzulin hatástartama 24 órásnak bizonyult. Az évtizedeken át
folyamatosan túladagolt egyszeri inzulinadás következménye a szinte naponta,
főként az éjjeli órákban fellépő hypoglykaemia lett, következményes nagyfokú
vércukor-ingadozásokkal. Az 1930-as évek közepétől a hatvanas évekig
polarimetriás, majd száraz kémiás módszerrel vizeletcukor-önellenőrzést végzett
a nyolcvanas évek elejéig, majd áttért a vércukor-önellenőrzésre. Az ötvenes
években két sikertelen terhessége volt, 2010–11-ben egymás után jobb, majd bal
oldali combnyaktörést szenvedett, majd mindkét szemén megműtötték a
cataractáját. Az utolsó 25 évben HbA1c-szintje 7% körül mozgott. Sem
retinopathia, sem nephropathia nem fejlődött ki nála, csupán súlyos neuropathia
okozott panaszokat az utolsó években. Emellett időskori száraz
maculadegeneratiója miatt látása folyamatosan romlott. Elnyerte a ’Joslin 75’
medált is. Élete utolsó két hónapjában engedte, hogy degludek + glulizin
inzulinnal intenzíven kezeljék. Halálát myocardialis infarctus okozta. Bár a
vércukor-ingadozások minimalizálása és a tartósan jó anyagcsere-vezetés
jelentősen javítja a diabetesesek életkilátásait, esetünkben jó fél évszázadon
keresztül egyik sem állt fenn. Ezért az extrém hosszú diabetestartamra nem
találtunk magyarázatot. Orv Hetil. 2020; 161(5): 193–197.
Nacimiento del judaísmo: Nehemías 8-10
Authors: Favaretto Bernardo
Published: January 2020

Los capítulos 8-10 de Nehemías se ubican como conclusión lógica de los libros de Esdras-Nehemías. La proclamación solemne de la Torah, en la plaza frente a la puerta de las Aguas, refleja la participación de todo el pueblo, la alegría de la escucha de la palabra, el revivir el camino del desierto y el compartir los alimentos. Todo se da como conclusión de la reconstrucción de la muralla y la organización social de Nehemías: fue un tiempo de nuevas esperanzas. El capítulo 9 inicia con la división de los sionistas, apoyados por los diaspórico de los pueblos de Judá y Samaria llamados “extranjeros”. Allí nace una nueva forma de ver y vivir la fe del Éxodo. Se cambia la Pascua por el Sinaí y la Misericordia Deuteronomísta por la Santidad. El Templo será sostenido por los sacerdotes, levitas y el pueblo sionista, que se compromete a contribuir con pesantes impuestos: las primicias de los frutos, el diezmo de sus propiedades y las primogenituras. Es el inicio de un judaísmo duro que marcará toda la historia de Israel hasta nuestros días.
An interview with Alan Warren, chair, British Dam Society
Authors: Pether Rachel
Published: January 2020

The following is an interview with the current chair of the British Dam Society (BDS), Alan Warren (Figure 1). Alan is a technical director and an all reservoirs panel engineer with Mott MacDonald based in Bristol. He is the company's global practice leader for dams and reservoirs, responsible for providing thought-leadership, guidance and innovation in related services.
Fragen über Fragen
Authors: Meier Christian
Published: January 2020

Reinhart Koselleck war Doktorant und an der Schwelle zu seinem dreißigsten Lebensjahr, as er am 21. Januar 1953 aus der Heidelberger Sandgasse seinen ersten Brief an Carl Schmitt schrieb. Über drei Jahrzehnte entspann sich in unterschiedlicher Dichte eine Korrespondez zwischen dem jungen Historiker und dem Staatsrechtler, der in den frühen fünfziger Jahren schon ein halbes Leben hinter sich hatte. Der Briefwechsel leuchtet aus der "Situation" der zweiten Hälfte des 20. Jahrhunderts stieg hinab in die Ideengeschichte und ist eine Schlüsselquelle für die intellektuelle Biographie Reinhart Kosellecks.
Fernwirkungen
Authors: Geulen Eva
Published: January 2020

Was den Unterschied zwischen politischer Philosophie und politischer Theorie genau ausmacht, lässt sich kaum trennscharf beschreiben. Ein Vorschlag zur Güte wäre die dsziplinäre Zuordnung. Dann tritt auch ins Bewusstsein, dass zwei wesentliche Gründungsfiguren der Politikwissenschaft der Weimarer Philosophie entstammen und welche enge Verbindung zur klassischen Ideengeschichte die Reflexion über Politik einst besaß.Dolf Sternberger war als philosophisch gebildeter Denker zweifellos eine Ausnahmeerscheinung unter den Nestoren der bundesrepublikanischen Politologie. Da der Schöngeist elegant schreiben konnte, hat man ihm lange Zeit den Weg zur Professur verbaut. Wie seine lebenslange Freundin Hannah Arendt war er von Heidegger fasziniert, kannte auch Karl Jaspers aus gemeinsamen Heidelberger Zeiten, wurde dann aber bei Paul Tillich über eine Heidegger-kritische Arbeit zum «verstandenen Tod» promoviert. Hannah Arendt fungierte sogar 1931 als Trauzeugin des Ehepaars Sternberger (und schenkte einen Mülleimer), blieb Heidegger aber philosophisch treu, der Jaspers für die Betreuung der Dissertation empfahl, damit Privates und Denkerisches getrennt bleiben konnte.
Aufrichtigkeit, Lüge und Verstellung
Authors: Stollberg-Rilinger Barbara
Published: January 2020

Wir haben es mit einer Zeit beschleunigten Wandels zu tun. Die sozialen Unterschiede verschärfen sich; es gibt Gewinner und Verlierer dieses Wandels. Viele fühlen sich durch die Dynamik abgehängt und sehen ihre altvertrauten Selbstverständlichkeiten bedroht. Ein Thema beherrscht den gesellschaftlichen Diskurs und wirkt in einem bisher unbekannten Ausmaß polarisierend; es provoziert jeden Einzelnen zur eindeutigen Parteinahme. Der Zwang zum Bekenntnis der richtigen Gesinnung nimmt zu, das wechselseitige Misstrauen steigt. Die Spaltung verläuft quer durch jedes Land, jede soziale Schicht, mitunter sogar quer durch die Familien. Gemäßgte, vermittelnde Stimmen haben es immer schwerer, sich Gehör zu verschaffen. Die gemeinsame Basis an fraglos geteilten Überzeugungen und Verfahren, auf der man sich über die feindlichen Lager hinweg verständigen kann, wird immer schmaler.
Als Adam Weishaupt einmal fast einen Musikabend verdorben hätte
Authors: Mulsow Martin
Published: January 2020

Man muss kein Verschwörungstheoretiker sein, um festzustellen, dass Adam Weishaupt, der Gründer des Illuminatenordens, ein ernster Zeitgenosse gewesen ist - ja: ein verschlossener, hölzerner und schroffer. An ihm schieden sich die Geister: Manche waren fasziniert vom feurigen Eindruck, andere aber auch schnell abgestoßen. Was uns fehlt, ist ein Ölporträt dieses düsteren Menschen. Wir kennen immer nur das harmlose, nichtssagende Kupferstich-Gesicht.
Interaction between Science Process Skills and Scientific Attitudes of Students towards Technological Pedagogical Content Knowledge
Authors: JUHJİ Juhji , NUANGCHALERM Prasart
Published: January 2020

The purpose of this research aims to study the interaction between scientific attitudes and science process skills toward technological pedagogical content knowledge. A survey research with an ex post facto design is employed. Data collection is carried out by direct observation, learning outcomes documents, questionnaire sheets which covered by science process skills, and scientific attitudes questionnaires. Seventy eight students were taken randomly. The research instruments consisted of 14 items about basic science process skills, 18 items about integrated science process skills, and 28 items about scientific attitudes. Data analysis used descriptive statistics, regression analysis, and multiple correlations. The results showed that 1) positive interactions between basic science process skills in TPCK, 2) negative interaction between integrated science process skills in TPCK, 3) positive interactions between scientific attitudes towards TPCK, and 4) the presence of joint interactions -the same between science process skills and scientific attitudes toward TPCK. Further discussion needs to be carried out why this happens to help students understand scientific attitudes, scientific process skills, and TPCK as well.
Indonesian Science Teachers’ Views on Attitude, Knowledge, and Application of STEM
Authors: PARMİN Parmin , SAREGAR Antomi , DETA Utama Alan , EL ISLAMİ R. Ahmad Zaky
Published: January 2020

This study
aims to describe Indonesian science teachers’ views on STEM attitude, STEM knowledge, and STEM application. The
survey method was used in this study.
Ninety-three Indonesian science teachers at junior
high schools in Indonesia from four of 11 provinces with the
largest number teachers such as Lampung, Banten, Jawa Tengah, and Jawa Timur were surveyed. The instrument in this study consisted of 30 items. The
quantitative analysis was performed to address the level of three domains such
as STEM attitude, STEM knowledge, and STEM application.
The results showed that Indonesian science
teachers’ views are very good on STEM attitude (=4.68), moderate-level
category on STEM application
(=3.99), and low-level
category on STEM knowledge (=3.72).
It can be concluded that Indonesian
science teachers believe that they have very good STEM attitude, moderate-level category on STEM application, and low-level
category on STEM knowledge. These findings recommended to science teachers or science educators in
Indonesia to promote STEM Education in the national curriculum especially in
science subject to improve STEM attitude, STEM knowledge, and STEM application of Indonesian
science teachers.
EASY AND INEXPENSIVE NUCLEIC ACID EXTRACTION PROTOCOL FOR RECALCITRANT SPECIES v1
Authors: P Matallana Ramirez Lilian , Kurt Yusuf , Kohlway William , Frampton John , Whetten Ross
Published: January 2020

Background: Some of the major contributions to the rapid genetic improvement of commercial plant species and crops come through the identification of genetic markers linked to specific traits with a marketable value that have been difficult or impossible to identify and improve with conventional methods. Next-Generation Sequencing (NGS) is a powerful platform that has enabled the exploration of the genome in different plant species. The success of NGS is dependent on the quality of DNA or RNA extracted. Methods and commercial kits for extraction of intact nucleic acids for many model plant species are available but the need exists still for high-throughput methods suitable for most non-model plants, in particular, recalcitrant plant species. Findings: - Our group has developed a detailed method that allows the isolation of genomic DNA or total RNA from different tissues from different plant species that yield enough material suitable for high-throughput SNP genotyping, sequencing applications and traditional downstream genetic analysis. - One single operator can extract nucleic acids from 192 samples in about 3.5 hours but the protocol is completely or partially-compatible with automation depending on available equipment. - We provide tips and comments that will help to improve the quality of the isolated material and solutions for everyday laboratory problems that will save time and money. - Little variations in the protocol allow the application of the method to plant tissues from fresh, dry or frozen samples. - The protocol is easy to set up in any molecular research laboratory, uses inexpensive reagents and handmade solutions that can be stored for several months, does not require the use of liquid nitrogen, and works best with 15 - 30 mg of fresh, frozen or dry plant material. - DNA and RNA have been isolated from at least 30 species, including especially recalcitrant forest trees from angiosperm and gymnosperm families. DNA has been also extracted from stored (2 to 6 years) silica-dried samples of species of Pinaceae and Nymphaeaceae families. - The protocol is a home-made adapatation of different published protocols that can be used in combination with different nucleic acids extraction kits. For reference consult: Ivanova, N.V. et al. 2006, Ivanova, N.V. et al 2008, and Whitlock R. et al. 2008.
Wuhan coronavirus (2019-nCoV) real-time RT-PCR ORF1ab 2020 (Wuhan-ORF1ab) v1
Authors: A Northill Judy , M Mackay Ian
Published: January 2020

A real-time RT-PCR to detect the "novel Wuhan" betacoronavirus or Wuhan seafood market pneumonia virus. Based on sequence MN908947 made available by Professor Yong-Zhen Zhang, Fudan University, Shanghai, China. The target region is within the ORF1ab sequence. Not tested on wild-type virus (as of 25Jan2020), it is expected to be capable of only detecting the Wuhan coronavirus. Notes Assay is fully optimised (as of 24Jan2020). A final name for this virus has not been decided (as of 25Jan2020).
Association between ABO blood group and uterine fibroids risk:a case-control study v1
Authors: Shen Changxin , Huang Shuang , Fu Yourong , Lin Chenyao , Yu Shuhong , Zhou Shuimei
Published: January 2020

The aim of this protocol was to conduct a case-control study between 2144 patients who had uterine fibroids and 1914 age-matched controls. Eligible patients were registered in Zhongnan Hospital of Wuhan University from January2017 to December 2018. Detailed informations of all participants, such as parity, menopausal status and menarche age wereobtained from electronic medical records. ABO blood group was detected by the examiners in the blood transfusion department through routine clinical trials. Unconditional multivariable logistic regression analysis was applied to evaluate the relationship between ABO blood group and uterine fibroids risk. All statistical analyses were performed by SPSS version21.0 for Windows and statistical significance was described as a P value <0.05. Gene chip data were downloaded from GEO(www.ncbi.nlm.nih.gov/geo) under the registration number GSE47577 and Differentially expressed genes (DEGs) between uterine fibroids and normal myometrium tissue samples were recognized by a web tool GEO2R(www.ncbi.nlm.nih.gov/geo/geo2r). DEGs were considered when an adjusted P < 0.05 and a |log2fold change|>1.0.
Protocol Temephos Bioassay v1
Authors: Ferrero Gomez Lara
Published: January 2020

Performing bioassays to assess the larval susceptibility to Temephos
TissueCyte Specimen Embedding Acrylamide Coembedding v1
Authors: Institute for Brain Science Allen
Published: January 2020

This protocol describes the preparation of a fixed mouse brain specimen bonded to an agarose block for blockface imaging and sectioning using the TissueCyte 1000 system.
Maintenance of TissueCyte System v1
Authors: Institute for Brain Science Allen
Published: January 2020

This protocols provides detailed instructions for procedures needed for maintenance of the TissueCyte scanning systems.
Mouse Genotyping with KAPA Kit in 2 Hours (#KK7302) v2
Authors: Wu Cq
Published: January 2020

This protocol uses KAPA Mouse Genotyping kit (#KK7302)
Redesign of a water quantity, quality, and sediment-monitoring network in a tropical region
Authors: Velez-Upegui Jorge Julian , Londoño-Carvajal Adela , Solorzano-Gómez Maria Valentina , Vélez-Upegui Jaime Ignacio , Botero-Fernández Verónica
Published: January 2020

The CORNARE region, located in Antioquia (Colombia), required a redesign of its water quantity, quality, and sediment-monitoring network, in order to collect convincing data to help decision-makers to respond to different technical and environmental issues. This paper proposes a methodology which is based on secondary information and which employs Geographical Information System –GIS- tools and knowledge of the region, given that historical data are unavailable in most of the region. Although the main methodology, which applied physical, anthropic, and economic factors was the same for all networks, specific strategies were used for water quantity, quality, and sediment networks in the region. These used expert criteria and weight distance methods. The results were satisfactory. Macro-location was implemented for the sites monitored in the CORNARE region, and this indicated that the proposed methodology was adequate for tropical Andean watersheds, where historical data were insufficient and did not permit the use of more complex techniques. This methodology integrates water quantity, water quality and sediment in an integrated hydrological monitoring network.
Simulation of Cr-III dispersion in the High Bogotá River Basin using the WASP model
Authors: Ramos Ramirez Luis Angel , Guevara Luna Marco Andres , Chiriví-Salomón Juan Sebastian , Muñoz Nieto Diana Marcela
Published: January 2020

The Bogotá River is the major river in Cundinamarca because it crosses the entire region from north to south. Industries from different economic activities have been established in the river, especially tanneries. Nevertheless, the current and traditional tanning process requires a large volume of water and generates tremendous environmental problems due to the chemical composition of dumpings that are discharged in the river. Chrome III (Cr III) is a persistent pollutant that represents a huge health public problematic because it can transform into Chrome VI, which is very harmful to the environment and people. Simulations carried out with this pollutant can help to establish a degree of pollution and monitoring and treatment spots in the river. For this reason, we aimed to simulate Cr III in a defined stretch of approximately 8 km along from Villapinzón. WASP model was chosen to simulate this pollutant with the study conditions, based on its software properties and similarities with previous studies. From our results, eight mixing zones were identified in the simulated stretch, which constitutes key points for water uptake for treatment and further applications. Dispersive coefficient, flow, and system geometry were identified as the main factors in the simulation. WASP efficiently simulated the system because observed and obtained data reached an index of agreement (IOA) of 0.975, which is higher than the criterium established for simulation. Experimental data can improve simulations to further understand the degree of pollution in the river.
Design, Construction and Evaluation of an Energy Harvesting Prototype built with Piezoelectric Materials
Authors: Echeverry Velasquez Alejandra , Velez Quintana Mateo , Posada-Montoya Jose Alejandro , Palacio-Fernandez José Alfredo
Published: January 2020

The piezoelectricity allows the generation of electric power taking advantage of the movement of vehicles and pedestrians. Many prototypes have been made with piezoelectric generators, but at present, their commercialization and use has not been popularized due to their low power generation and energy losses. A design of an experimental prototype of an energy harvester with piezoelectric materials that reduces these losses and generates more energy thanks to the resonance with the beams is proposed in this article. An equilateral triangular tilde is designed such it will not deform when a force act on it. The tilde has four-cantilever beams, and it is designed to resonate with the natural frequency of the piezoelectric material. This is coupled to the piezoelectric device. The vibration generated on the beam, by average of a mechanical load, is used to generate more energy when it resonates. The piezoelectric is a ceramic material and generates a nominal power of 75 mW before placing it on the beam, and 375 mW after being placed on the beam. However, the energy collection circuit has losses due to its own consumption, the transmission of energy to the storage system, and in the mechanical system.
Improving Farm Management Information Systems with Data Mining
Authors: CATAL Cagatay , KASSAHUN Ayalew , HOVİNG Henk Jan
Published: January 2020

Over the past several
years, farm enterprises have grown in size substantially while their number has
steadily declined. As the size of their farms grow more and more farmers are
deploying information systems, commonly called as Farm Management Information
Systems (FMIS), to manage the day to day activities of their farms. The
deployment of FMIS enable farmers to capture detailed data that can potentially
be analysed by data mining tools to provide valuable information for optimizing
the farm enterprises. However, data mining is generally not a common feature of
many FMIS. In order to evaluate the suitability of data mining for use in FMIS,
we performed two case studies using data captured in FMIS and applying data
mining. Microsoft Azure Machine Learning Studio is chosen because it provides a
simple drag-and-drop visual interface that can be used by farm domain experts.
We addressed two common problems in dairy farming: calving prediction of dairy
cows and prediction of lactation value of milking cows. In both cases we built
data mining models and run experiments and our results in both cases indicate
that the required data is available from FMIS and data mining techniques provides
acceptable performance. We also showed that farm domain experts can easily use
a user-friendly and drag-and-drop data mining tools with minimal initial
training. Based on the insight from the two case studies and literature study, we
identified several decision problems that can be addressed with data mining such
as heat prediction and  lameness prediction.
INTERACTION OF POWER AND SOCIETY WITHIN THE FRAMEWORK OF THE ASSOCIATION AGREEMENT BETWEEN UKRAINE AND THE EU AND EASTERN PARTNERSHIP POLICY PAPERS
Authors: Vnuchko Svitlana
Published: January 2020

Communication of public authorities and society, in particular, public authorities and separate social groups, is an important component of the political and managerial practice of modern society.
The world practice shows that effective communication between these actors provides citizens with free access to information, improves the efficiency of government and local self-government bodies, and creates a favourable environment for business development, which in turn serves as the basis for economic stability and the engine of the country’s social and economic development.
In the conditions of the development of the information society, new models, mechanisms, platforms of relations and communication between the authorities and the public are emerging. The constructive interaction between power structures and civil society organizations, with a «feedback» component, will contribute to meeting the needs and interests of citizens and strengthening the credibility of both power structures and civil society institutions. Moreover, it will improve the status of Ukraine at the international level by ensuring compliance with the Association Agreement and creating the preconditions for Ukraine to achieve the 20 key priorities of the Eastern Partnership 2020. In the future, consideration should be given to this issue in order to deepen, broaden and improve the effectiveness of the communication component of the government bodies and civil society organizations in Ukraine.
In the implementation of communication interaction, special attention should be paid to providing a feedback between communicators. After all, it is this component of the communications process that provides interaction and information about the society’s reaction to the results of the implemented decisions.
Purpose of the research: to conduct a scientific, theoretical and practical analysis of functioning of the existing in Ukraine communication platforms of civil society organizations and authorities in the framework of the Association Agreement and the Eastern Partnership policy papers.
THE GERMAN CONJUNCTIVE AND THE MODAL MEANING OF “IRREALITY” (IN FRAMES OF THE SIMPLE SENTENCE
Authors: Kozlovskyi V.W.
Published: January 2020

The article investigates the specificity of the German conjunctive within the construction of structural und semantic models. It is proved that the form of Konj. Präteritum is the means in to individualize the simple sentence in the aspect of its structural and semantic organization
OTOMATİK DÜŞÜNCELERİN YORDAYICILIĞI: UMUT VE UMUTSUZLUK FARKI
Authors: Artıran Murat , Şeker Alperen
Published: January 2020

Bu çalışmanın temel amacı, bilişsel terapide
tedavi uygulamalarının ana öğelerinden biri olan negatif otomatik düşüncelerin umut
değişkeni ve umutsuzluk değişkeni ile ilişkisi ortaya konulmak istenmiştir. Araştırmaya
özel sektör çalışanlarından kolaydan örnekleme yöntemiyle seçilen 74’ü kadın 123 erkek olmak üzere
toplamda 197 katılımcı iştirak etmiştir. Verilerin incelenmesinde spearmen
korelasyon ve çoklu doğrusal regresyon analizi kullanılmıştır. Elde edilen
bulgulara göre negatif otomatik düşüncelerin, yaşam projesi ölçeği değişkenlerinden
olan ‘pozitif’ umut değişkenini yordamadığı gözlenlenmiştir. Öte yandan Beck
Umutsuzluk Ölçeği ile kavramsallaştırılan umutsuzluk ile güçlü bir ilişkisellik
içinde olduğu ve yordadığı bulgulanmıştır. Bu çalışmada kullanılan veri setiyle
sınırlı olmak üzere, negatif otomatik düşüncelerin psikolojideki pozitif yapılarla
ilişkisellik içerisinde olduğu ancak bu değişkenleri etkilemediği söylenebilir.
Gelecekteki çalışmalarda bilişsel terapinin sadece psikolojideki olumsuz
değişkenlerle değil pozitif psikoloji değişkenleri ile test edilmesi
önerilebilir
ASKERİ DENİZALTILARIN İÇ MEKAN KURGULARININ ERGONOMİ KAPSAMINDA İRDELENMESİ
Authors: Kılıç Onur
Published: January 2020

Mekan tasarımı, uzayın sonsuz boşluğu içerisinde
sınırlandırılan ve kullanıcı ile etkileşim halinde olan her türlü hacmin kurgulanması
ile ilgilenir. Bu hacimlerin, kullanıcıların en verimli şekilde kullanımına imkan
verecek şekilde düzenlenmesi mekan tasarımının temel amacını oluşturur. Ancak
iç mekan tasarımındaki farklı gereksinimler ve buna göre şekillenen kazanımlar değişkenlik
göstermektedir. Bu değişkenlik işlevsel farklılığın dışında, sınırlı hacimde
çözülmesi gereken ihtiyaçlar ve öncelikler nedeniyle ortaya çıkmaktadır. Mobil mekan-yapı
türlerinin hepsi için bu “sınırlı alanda tasarım” zorunluluğu geçerlidir. Bu zorunluluk
bir tasarım sorunsalı olarak görülmüş ve çok sayıda mürettebatın uzun süre
boyunca birlikte yaşamak zorunda olduğu askeri denizaltılar inceleme konusu
olarak seçilmiştir. Bu seçimde askeri araçların iç mekan tasarımları ile ilgili
çalışmaların azlığı ve bu alana dikkat çekme ihtiyacı duyulması da etkili
olmuştur. Bu çalışmada sınıf ve yıl farkı gözetmeksizin bütün askeri
denizaltılar kapsam dahilinde tutulmuş, iç mekan tasarım yaklaşımları ergonomi ilkeleri
temel alınarak yorumlanmıştır.
OKUL MÜDÜRÜ GERİ BİLDİRİM ÖLÇEĞİ GEÇERLİK VE GÜVENİRLİK ÇALIŞMASI
Authors: Balcı Suphi , Özkan Habib
Published: January 2020

Okul müdürlerinin
verdiği geri bildirimlerin etkililiği öğretmenlerin mesleki olarak
gelişimlerinde önemli etkenler arasında sayılmaktadır. Bu bağlamda okul
müdürlerinin öğretmenlere verdiği geri bildirimlerin etkililiğini ölçecek bir
ölçme aracı geliştirmek bu araştırmanın amacını oluşturmaktadır. Ölçek
maddeleri yazılırken hem etkili geri bildirimin işe vuruk tanımına hem de
etkili geri bildirim veren okul müdürü davranışlarına uygunluğuna dikkat edilerek
literatür taranmıştır. Kapsam geçerliği için 7 alan uzmanından görüş alındıktan
sonra ölçek açımlayıcı faktör analizi için önce Hatay ili Antakya ilçesindeki
resmi ortaokullarda görevli 363 öğretmene, sonra doğrulayıcı faktör analizi
için İskenderun ilçesindeki 315 öğretmene uygulanmıştır. Temel Bileşen Analizi
tekniğinin seçildiği ve dik döndürme yöntemlerinden Varimax’ın kullanıldığı faktör
analizi sonucunda her biri 17 maddeden oluşan iki boyut elde edilmiştir. Elde
edilen boyutlar “süreç” ve “işlev” olarak isimlendirilmiştir. Ölçeğin
açıkladığı toplam varyans %76.887 olarak bulunmuştur. Doğrulayıcı faktör
analizi ile ölçeğin model
uygunluk ölçütleri bakımından iyi ve kabul edilebilir uyum aralığında olduğu
sonucuna ulaşılmıştır. Ölçeğin güvenirlik katsayısı Cronbach’s Alfa katsayısı
ve iki yarı test istatistik teknikleri kullanılarak hesaplanmıştır. Her iki
analiz sonucunda da elde edilen değer hem ölçeğin bütünü ve alt boyutlarda
.90’nın üzerindedir. Sonuç olarak, yapılan analizler okul müdürü geri bildirim
ölçeğinin geçerli ve güvenilir bir ölçek olduğunu göstermektedir.
ZAMAN YÖNETİM BECERİLERİNİN AKADEMİK BAŞARI İLE İLİŞKİ
Authors: Akyüz Müslüme , Taşkın Yılmaz Feride , Aldemir Kadriye
Published: January 2020

Araştırma
zaman yönetimi becerilerinin akademik başarı ile ilişkisini ortaya koymak
amacıyla yapılmıştır. Tanımlayıcı ve ilişkisel olarak gerçekleştirilen
çalışmaya, bir üniversitenin Hemşirelik bölümünde öğrenim gören ve çalışmaya
katılmayı kabul eden 562 öğrenci dahil edilmiştir. Öğrencilerin zaman yönetimi
beceri düzeylerinin orta derecede olduğu belirlenmiştir. Öğrencilerin akademik
başarı not ortalaması ile Zaman Yönetimi Envanteri’nin zaman planlaması ve
zaman harcattırıcılar alt boyutu puan ortalamaları arasında anlamlı bir
farklılık saptanmazken; akademik başarı not ortalaması yüksek olan öğrencilerin
zaman yönetimi uygulamalarının daha iyi olduğu, zamanlarını iyi yönettikleri ve
planlamalarında uzun zaman aralığını gözettikleri tespit edilmiştir. Ayrıca
çalışmada zaman yönetimi genel ve zaman tutumları alt boyut değişkenlerinin
akademik başarı üzerinde anlamlı bir yordayıcı olduğu belirlenmiştir.
Hemşirelik öğrencilerin zaman yönetimi becerilerinin orta düzeyde olduğu ve
zaman yönetimi becerilerinin akademik başarıyı önemli derecede etkilediği
belirlenmiştir.
TARIMSAL YAYIMDA KİTLE İLETİŞİM ARAÇLARI VE ZİRAAT FAKÜLTESİ ÖĞRETİM ELEMANLARININ TARIM TEMALI TELEVİZYON KANALLARINA KARŞI TUTUMLARI
Authors: Sert Mustafa , Sevinç Mehmet Reşit , Cançelik Mehmet , Aydoğdu Mustafa Hakki
Published: January 2020

Bu
çalışma, ziraat fakültelerinde görev yapan öğretim elemanlarının, tarım temalı
televizyon kanallarına karşı tutumlarını ortaya koymak amacıyla yapılmıştır. Bu
araştırmanın ana materyalini; Türkiye’de ki ziraat fakültelerinde görev yapan öğretim
elemanlarından anket yöntemi ile elde edilen birincil veriler oluşturmaktadır.
YÖK akademi kayıtlarına göre ilgili alanda Türkiye’de toplam 4728 öğretim
elemanı bulunmaktadır. Anket formu elektronik posta yöntemi ile tüm öğretim elemanlarına
gönderilmiş olup, 312 geri dönüş olmuştur. Bu örneklem büyüklüğü; %95 güven
seviyesi ve ±%5,36 hata payına karşılık gelmektedir. Katılımcılara sorulan 16
likert ölçekli soruya faktör analizi uygulanmış, ifadeler dört faktör başlığı
altında toplanmıştır. Katılımcılara göre tarım temalı TV ler çok yüksek düzeyde
olmasa da tarımsal ilgi ve gelişime olumlu bir katkı sağlamaktadır (genel
ortalama 3.55) ancak paydaşlarla iletişimi yeterli düzeyde değildir (genel
ortalama 2.85). Katılımcılar tarım temalı TV kanallarının program içeriklerinin
teknik yeterliliğinin çok yüksek düzeyde olmadığını (genel ortalama 2.97) bu
nedenle akademisyenlerden daha çok yararlanılması gerektiğini belirtmiştir (genel
ortalama 4.05). Tarım temalı TV kanalları tarımsal yayım ve gelişimde önemli
bir rol üstlenmektedir. Bu önemli sorumluluk yerine getirilirken, hazırlanan
programların teknik içerikleri uzman kadrolarca ve özellikle alanında uzman
akademisyenlerce hazırlanmalı ya da denetlenmelidir. Üreticilerde motivasyonun
arttırılmasına yönelik yarışmalara ve başarı öykülerine daha çok yer
verilmelidir.
JuSPARC - The Jülich Short-Pulsed Particle and Radiation Center
Authors: Büscher Markus , Adam Roman , Tusche Christian , Hützen Anna , Wiemann Carsten , Chen Ying-Jiun , Schneider Claus M.
Published: January 2020

JuSPARC, the Jülich Short-Pulsed Particle and Radiation Center, is a laser-driven facility to enable research with short-pulsed photon and particle beams to be performed at the Forschungszentrum Jülich. The conceptual design of JuSPARC is determined by a set of state-of-the-art time-resolved instruments, which are designed to address the electronic, spin, and structural states of matter and their dynamic behaviour. From these instruments and experiments JuSPARC derives the need of operating several dedicated high pulse-power laser systems at highest possible repetition rates. They serve as core units for optimized photon up-conversion techniques generating the light pulses for the respective experiments. The applications also include experiments with spin polarized particle beams, which require the use of laser-based polarized gas targets. Thus, in its rst stage JuSPARC comprises four driving laser systems, called JuSPARC_VEGA, JuSPARC_DENEB, JuSPARC_SIRIUS and JuSPARC_MIRA, which are outlined in this article.
Remodeling of the heart and main vessels in patients with marfanoid habitus
Authors: Timofeev Eugene V. , Malev Eduard G. , Parfenova Nina N. , Zemtsovsky Eduard V.
Published: January 2020

For many hereditary connective tissue disorders (HCTD), especially Marfan syndrome, remodeling of the heart and main vessels is described, which is manifested by a decrease in the systolic function of the left ventricle and expansion of the thoracic aorta. Evaluation of morphometric characteristics of the heart and main vessels in patients with other HCTD, in particular marfanoid habitus (MH) has not been previously carried out.

Materials and methods. Weexamined 90 young men and 74 young women between the ages of 18 to 25 years, 111 patients older age groups with stable over coronary heart disease (mean age 64.66.2 years) and 9 patients with verified Marfan syndrome (mean age 27.99.3years). All survey phenotypic and performed anthropometric survey identifying bone signs of dysembryogenesis as well as Echocardiography study on standard protocol.

The results.Patients with MH as compared with control group revealed a relatively larger diameter of aortic root (30.44.7 vs 28.03.6 mm,p= 0.03) and the ascending aorta (26.64.9 vs 24.63.2 mm,p= 0.05). Also young with MH turned out to be significantly thicker myocardium of left ventricular posterior wall (8.30.8 vs 7.71.1 mm,p= 0.02) and interventricular septum (8.81.2vs 8.21.1mm,p= 0.04). When performing correlation analysis identified reliable positive correlation between such highly specialized bone signs as high palate (r= 0.31), infundibular deformation of the chest (r= 0.43), arachnodactyly (r= 0.45) andZ-test (p 0.05 for all). Expansion of the aorta (Z-criterion 2.0) have found 24% of older patients with MH.

Conclusion.Inpatients with MH revealed significant structural changes of heart and main vessels which are progredient character thickening of the left ventricular myocardium and expansion of the aortic root.
Gastrointestinal risk factors for anemia in children with celiac disease
Authors: Shapovalova Natalia S. , Novikova Valeriya P. , Revnova Maria O. , Gurina Olga P. , Dementieva Elena A. , Klikunova Ksenia A.
Published: January 2020

With oral intake, iron absorption in patients with celiac disease (CD) is reduced due to the decreased absorption surface of the atrophic small intestine mucous membrane. Besides, there are additional risk factors for anemia whose mechanisms are unclear.The aimof this study was to evaluate gastrointestinal risk factors for anemia in children.

Materialsand methods.The first group consisted of 58 children with newly diagnosed CD who did not adhere to the gluten-free diet(GFD). The second group included 49 children with CD who hasnt been adhering to the GFD. The third group included 69children with chronic gastritis (CG) without CD. In addition to the standard examination, which includes the determination of antibodies to tissue transglutaminase and histological examination of the duodenum mucous membrane, a histological evaluation of the gastric mucosa, determination of pepsinogen 1 and 2 and their ratio, antibodies to Castles intrinsic factor were performed.

Results.The mean level of hemoglobin in the group 1114,71120,10125,50g/l, in the group 2124,37128,74133,10g/l, in the group 3130,12133,78137,43g/l (p1,2=0.013;p1,3=0,000;p2,3=0.083). A correlation analysis of the hemoglobin level and morphological parameters of the duodenal mucosa among the studied patients revealed an inverse moderate correlation between the hemoglobin level and the degree of the small intestinal atrophy according to Marshr=0.331,p=0,000, crypt depthr=0,439,p=0,000, and a moderate direct with the ratio of villi:cryptr=0.417,p=0.000, with the height of the villir=0.366,p=0,000. Additionally, a moderate direct correlation between the level of hemoglobin and the number of parietal cells was found to ber=0.354,p=0.037. In group 1, a significant inverse correlation between the level of hemoglobin and the level of antibodies to Castles factorr=0.529,p=0.006, was obtained for the level of antibodies in the Castles factor.

Conclusion.Autoimmune gastritis may be an additional risk factor in combination with malabsorption, as a possible cause of anemia in children with CD.