bluuebunny/crossref_metadata_2025 huggingface dataset:
ChemInform Abstract: Ruthenium‐Catalyzed Directing Group‐Free C2‐Selective Carbenoid Functionalization of Indoles by α‐Aryldiazoesters.
Authors: Chan Wai‐Wing , Yeung Shing‐Hin , Zhou Zhongyuan , Chan Albert S. C. , Yu Wing‐Yiu
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Gold(I)‐Catalyzed One‐Pot Reaction Between 2‐Alkynylanilines and Alkynols Leading to the Formation of C‐3‐Substituted Indoles: A Case of Formal Carboamination of Alkynes.
Authors: Patil Nitin T. , Singh Vipender , Konala Ashok , Mutyala Anil Kumar
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Asymmetric Hydrogenation of 2‐Substituted N‐Protected Indoles (II), (IV) Catalyzed by Rhodium Complexes of BINOL‐Derived Phosphoramidites.
Authors: Mrsic Natasa , Jerphagnon Thomas , Minnaard Adriaan J. , Feringa Ben L. , de Vries Johannes G.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Catalytic Oxyamidation of Indoles.
Authors: Beaumont Stephane , Pons Valerie , Retailleau Pascal , Dodd Robert H. , Dauban Philippe
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Three‐Component Reaction Based on a Remote‐Group‐Directed Dynamic Kinetic Aza‐Michael Addition: Stereoselective Synthesis of Imidazolidin‐4‐ones.
Authors: Xu Zhenghu , Buechler Tyler , Wheeler Kraig , Wang Hong
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Oxazoles Through Pd‐Catalyzed Cycloisomerization—Allylation of N‐Propargylamides with Allyl Carbonates.
Authors: Saito Akio , Iimura Koichi , Hanzawa Yuji
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: General Methodology for the Preparation of 2,5‐Disubstituted‐1,3‐oxazoles.
Authors: Williams David R. , Fu Liangfeng
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A New Practical Synthesis of Linezolid: An Antibacterial Drug.
Authors: Reddy Ganta Madhusudhan , Ramulu Akula , Reddy Padi Pratap
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Palladium‐Catalyzed Direct Arylations, Alkenylations, and Benzylations Through C—H Bond Cleavages with Sulfamates or Phosphates as Electrophiles.
Authors: Ackermann Lutz , Barfuesser Sebastian , Pospech Jola
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Efficient and Regioselective Synthesis of 5‐Hydroxy‐2‐isoxazolines: Versatile Synthons for Isoxazoles, β‐Lactams, and γ‐Amino Alcohols.
Authors: Tang Shibing , He Jinmei , Sun Yongquan , He Liuer , She Xuegong
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Aluminum(salen) and Tetrabutylammonium Bromide Catalyzed Synthesis of Cyclic Di‐ and Trithiocarbonates from Epoxides and Carbon Disulfide.
Authors: North Michael , Villuendas Pedro
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Palladium‐Catalyzed Alkenylation of 1,2,3‐Trizoles with Terminal Conjugated Alkenes by Direct C—H Bond Functionalization.
Authors: Jiang Huanfeng , Feng Zhenning , Wang Azhong , Liu Xiaohang , Chen Zhengwang
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Cheap Amino Alcohol Catalyzed One‐Pot, Tri‐Component Synthesis of Tetrahydrochromene Derivatives.
Authors: Song Shaojun , Shan Zixing , Jin Yong
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Facile Synthesis of Pyrrolo[2,3‐b]quinolines via a Rh(I)‐Catalyzed Carbodiimide‐Pauson—Khand‐Type Reaction.
Authors: Saito Takao , Furukawa Naoki , Otani Takashi
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Rh2(OAc)4‐AgOTf Cooperative Catalysis in Cyclization/Three‐Component Reactions for Concise Synthesis of 1,2‐Dihydroisoquinolines.
Authors: Guo Zhenqiu , Cai Mei , Jiang Jun , Yang Liping , Hu Wenhao
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: 2,3‐Bis(phenylsulfonyl)‐1,3‐butadiene as a Reagent for the Synthesis of the Azatricyclic Core (IX) of (.+‐.)‐Halichlorine.
Authors: Flick Andrew C. , Caballero Maria Jose Arevalo , Lee Hyoung Ik , Padwa Albert
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Concise Synthesis of Fluorine‐Containing Benzo[h]quinolines and Benzo[h]quinolones by Selective Pyridine and Pyridinone Rings Formation Reactions of N‐Propargyl‐2,4‐bis(trifluoroacetyl)‐1‐naphthylamine with Various Active Methylene Compounds.
Authors: Okada Etsuji , Shibata Dai , Tsukushi Norikado , Dohura Masato , Ota Norio , Adachi Satoru , Medebielle Maurice
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of a 6H‐Chromeno[3,4‐b]quinoline and a 6a,12a‐Dehydro‐7‐azarotenoid.
Authors: Morris Andrew L. C. , Jackson Yvette A.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis, Antitumor, and Electrochemical Behavior of Some Piperazinyl Amidrazones.
Authors: Abdel‐Jalil Raid Jamil , El Momani Ehab Q. , Hamad Muawiah , Voelter Wolfgang , Mubarak Mohammad S. , Smith Bianna H. , Peters Dennis G.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Discovery of Benzhydrylpiperazine Derivatives as CB1 Receptor Inverse Agonists via Privileged Structure‐Based Approach.
Authors: Meng Tao , Wang Jue , Peng Hongli , Fang Guanghua , Li Min , Xiong Bing , Xie Xin , Zhang Yongliang , Wang Xin , Shen Jingkang
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: β‐Diketiminate Zinc Complexes for the Hydroamination of Alkynes.
Authors: Biyikal Mustafa , Loehnwitz Karolin , Meyer Nils , Dochnahl Maximilian , Roesky Peter W. , Blechert Siegfried
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chlorotrimethylsilane‐Promoted Synthesis of 1,2‐Dihydro‐1‐arylnaphtho[1,2‐e][1,3]oxazine‐3‐ones.
Authors: Jiang Chenggang , Geng Xin , Zhang Zonglei , Xu Hangxian , Wang Cunde
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: One‐Pot Aryl‐1,4‐thiomorpholine 1,1‐Dioxide Synthesis via Double 1,4‐Addition of in situ Reduced Nitroarenes to Divinyl Sulfones.
Authors: Han Joon Hee , Choi Jaehwan , Jun Young Moo , Lee Byung Min , Kim Byeong Hyo
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Enantioselective Synthesis of a 2,2‐Disubstituted Tetrahydro‐3‐benzazepine as Novel NMDA Receptor Antagonist.
Authors: Husain Syed Masood , Froehlich Roland , Schepmann Dirk , Wuensch Bernhard
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A New Route to 1,4‐Oxazepanes and 1,4‐Diazepanes from Garner Aldehyde.
Authors: Das Sanjit Kumar , Srivastava Ajay Kumar , Panda Gautam
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Allylic Substitution versus Suzuki Cross‐Coupling: Capitalizing on Chemoselectivity with Bifunctional Substrates.
Authors: Hussain Mahmud M. , Walsh Patrick J.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Ultrasound‐Promoted Greener Approach to Synthesize α‐Hydroxy Phosphonates Catalyzed by Potassium Dihydrogen Phosphate under Solvent‐Free Condition.
Authors: Mandhane Priyanka G. , Joshi Ratnadeep S. , Nagargoje Deepak R. , Gill Charansingh H.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chiral N‐Phosphonyl Imine Chemistry: An Efficient Asymmetric Synthesis of Chiral N‐Phosphonyl Propargylamines.
Authors: Kaur Parminder , Shakya Gaurav , Sun Hao , Pan Yi , Li Guigen
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Burkholdines 1097 and 1229, Potent Antifungal Peptides from Burkholderia ambifaria 2.2N.
Authors: Tawfik Kamilia A. , Jeffs Peter , Bray Brian , Dubay George , Falkinham Joseph O. III , Mesbah Mostafa , Youssef Diaa , Khalifa Sherief , Schmidt Eric W.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Cephastigiamide A, and Antiplasmodial Activity of Cephalotaxus Alkaloids from Cephalotaxus harringtonia Forma fastigiata.
Authors: Morita Hiroshi , Nagakura Yuta , Hosoya Takahiro , Ekasari Wiwied , Widyawaruyanti Aty , Mori‐Yasumoto Kanami , Sekita Setsuko , Hirasawa Yusuke
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A New Tetrahydrophenanthrene from Chloranthus henryi
Authors: Fu Hui Zheng , Luo Yong Ming , Liu Hua , Zhang Dong Ming , Ji Teng Fei
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Cyclohexanone Derivatives from Senecio argunenis
Authors: Tian Yong Qiang , Niu Yu Fang , Shen Tong , Weng Cheng Wu , Xie Wei Dong , Row Kyung Ho
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of 7,8‐Methylenedioxy‐4′‐methoxyisoflavone (III) from Indigofera linnaei and Two New Related Flavonoids.
Authors: Menezes Jose C. J. M. D. S. , Kirtany Janardan K. , Kamat Shrivallabh P.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Cytosporones O (I), P (IIa) and Q (IIb) from an Endophytic Cytospora sp.
Authors: Abrei Lucas M. , Phipps Richard K. , Pfenning Ludwig H. , Gotfredsen Charlotte H. , Takahashi Jacqueline A. , Larsen Thomas O.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Total Synthesis of the Polycyclic Fungal Metabolite (.+‐.)‐Communesin F (I).
Authors: Liu Peng , Seo Jae Hong , Weinreb Steven M.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Walkmycin B Targets WalK (YycG), a Histidine Kinase Essential for Bacterial Cell Growth.
Authors: Utsumi Ryutaro , et al. et al.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: JBIR‐69, a New Metabolite from Streptomyces sp. OG05.
Authors: Fujiwara Takeshi , Nagai Aya , Takagi Motoki , Shin‐ya Kazuo
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: PbTiO3 Nanofibers with Edge‐Shared TiO6 Octahedra.
Authors: Han Gaorong , et al. et al.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Quest for New Materials: Inorganic Chemistry Plays a Crucial Role
Authors: Gopalakrishnan J. , Mani Rohini
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Manganese, Technetium and Rhenium
Authors: West Andrew J.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Halogens and Noble Gases
Authors: Justik Michael W.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Bisazines in the Coordination Sphere of Early Transition Metals
Authors: Beckhaus Ruediger
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Structure and Characteristics of the Ionic Forms of Heteroarenium Salts in Organic Solvents
Authors: Shvaika O. P. , Kovach N. A.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Discovery of the Michael Reaction
Authors: Tokoroyama Takashi
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Syntheses of Antiviral Agents from the Family of Acyclic Nucleoside Phosphonates and Their Prodrugs
Authors: Krecmerova Marcela , Holy Antonin
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Stitching Together Palau′amine
Authors: Romo Daniel
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Directing Iridium‐Catalyzed C—C Bond Formation by Selection of the Ancillary Ligands: Polymerization and Cyclotrimerization of Alkynes
Authors: Farnetti Erica , Filipuzzi Serena
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Multicomponent Heterocycle Syntheses via Catalytic Generation of Alkynones
Authors: Willy Benjamin , Mueller Thomas J. J.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Multicomponent Reactions Using Indium(III) Salts
Authors: Yadav Jhillu S. , Antony Aneesh , George Jimil , Reddy Basi V. Subba
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Multicomponent Synthesis of Cyclic Frameworks on Knoevenagel‐Initiated Domino Reactions
Authors: Han Yi‐Feng , Xia Min
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Exploring the Supramolecular Coordination Chemistry Based Approach for Nanotechnology
Authors: Toma Henrique E. , Araki Koiti
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Applications of Dioxomolybdenum(VI) Complexes to Organic Synthesis
Authors: Sanz Roberto , Pedrosa Maria R.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Silver‐Mediated Oxidation Reactions: Recent Advances and New Prospects
Authors: Li Zigang , Capretto David A. , He Chuan
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Properties of Three‐ and Four‐Membered Carbocyclic Compounds
Authors: Benedetti Fabio
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Recent Advances in Noble Metal Nanocatalysts for Suzuki and Heck Cross‐Coupling Reactions
Authors: Narayanan Radha
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Asymmetric Reactions in Total Synthesis
Authors: Nicolaou K. C. , Bulger Paul G.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Pd(II)/HPMoV‐Catalyzed Direct Oxidative Coupling Reaction of Benzene Derivatives with Olefins
Authors: Obora Yasushi , Ishii Yasutaka
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Towards the Elusive Structural of Kotalanol, a Naturally Occurring Glucosidase Inhibitor
Authors: Mohan Sankar , Pinto B. Mario
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Fluorogenic Click Reaction
Authors: Le Droumaguet Celine , Wang Chao , Wang Qian
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Application of CuAAC “Click” Chemistry to Catenane and Rotaxane Synthesis
Authors: Haenni Kevin D. , Leigh David A.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: In situ Click Chemistry: Probing the Binding Landscapes of Biological Molecules
Authors: Mamidyala Sreeman K. , Finn M. G.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Selenium Derivatization of Nucleic Acids for X‐Ray Crystal‐Structure and Function Studies
Authors: Sheng Jia , Huang Zhen
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Click Chemistry under Non‐Classical Reaction Conditions
Authors: Kappe C. Oliver , Van der Eycken Erik
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Peptide Nucleic Acids (PNA) in Chemical Biology and Drug Discovery
Authors: Nielsen Peter E.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Kinetic Target‐Guided Synthesis
Authors: Hu Xiangdong , Manetsch Roman
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Activation and Regulation of Nociceptive Transient Receptor Potential (TRP) Channels, TRPV1 and TRPA1
Authors: Tominaga Makoto
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Monocyclic Hetarenes with π‐Electron Aromatic Sextet
Authors: Balaban Alexandru T.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Fragment‐Based Screening by X‐Ray Structure Analysis
Authors: Yamano Akihito
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Stereoselective metabolism of benalaxyl in liver microsomes from rat and rabbit
Authors: Zhang Ping , Zhu Wentao , Dang Ziheng , Shen Zhigang , Xu Xinyuan , Huang Ledan , Zhou Zhiqiang
Published: June 2010

Benalaxyl (BX), methyl‐N‐phenylacetyl‐N‐2,6‐xylyl alaninate, is a potent acylanilide fungicide and consist of a pair of enantiomers. The stereoselective metabolism of BX was investigated in rat and rabbit microsomes in vitro. The degradation kinetics and the enantiomer fraction (EF) were determined using normal high‐performance liquid chromatography with diode array detection and a cellulose‐tris‐(3,5‐dimethylphenylcarbamate)‐based chiral stationary phase (CDMPC‐CSP). The t1/2 of (−)‐R‐BX and (+)‐S‐BX in rat liver microsomes were 22.35 and 10.66 min of rac‐BX and 5.42 and 4.03 of BX enantiomers. However, the t1/2 of (−)‐R‐BX and (+)‐S‐BX in rabbit liver microsomes were 11.75 and 15.26 min of rac‐BX and 5.66 and 9.63 of BX enantiomers. The consequence was consistent with the stereoselective toxicokinetics of BX in vitro. There was no chiral inversion from the (−)‐R‐BX to (+)‐S‐BX or inversion from (+)‐S‐BX to (−)‐R‐BX in both rabbit and rat microsomes. These results suggested metabolism of BX enantiomers was stereoselective in rat and rabbit liver microsomes. Chirality, 2011. © 2010 Wiley‐Liss, Inc.
High performance liquid chromatography enantioseparation of the novel designed mexiletine derivatives and its analogs
Authors: Zheng Chengzhen , Zhang Datong , Wu Qi , Lin Xianfu
Published: June 2010

A series of novel designed mexiletine derivatives and its analogs were prepared, the structures were confirmed by Nuclear Magnetic Resonance (NMR), Fourier Transform Infrared Spectroscopy (FTIR), and Electrospray Ionization‐Mass Spectrometry (ESI‐MS), and the enantioseparations were performed on polysaccharide‐based chiral stationary phase (CSP), Chiralcel OD‐H, and Chiralcel OJ‐H, under normal‐phase mode. The effects of the concentration of isopropanol in the mobile phase were studied, seven of the eight enantiomers got baseline separation on Chiralcel OD‐H, and five of the eight enantiomers got successfully separation on Chiralcel OJ‐H. The effects of structural features were also discussed. Chirality, 2011. © 2010 Wiley‐Liss, Inc.
A Combined High‐Resolution Mass Spectrometric and in silico Approach for the Characterisation of Small Ligands of β2‐Microglobulin
Authors: Regazzoni Luca , Bertoletti Laura , Vistoli Giulio , Colombo Raffaella , Aldini Giancarlo , Serra Massimo , Carini Marina , Caccialanza Gabriele , De Lorenzi Ersilia
Published: June 2010

β2‐Microglobulin (β2‐m) is a protein responsible for a severe complication of long‐term hemodialysis, known as dialysis‐related amyloidosis, in which initial β2‐m misfolding leads to amyloid fibril deposition, mainly in the skeletal tissue. Whereas much attention is paid to understanding the complex mechanism of amyloid formation, the evaluation of small molecules that may bind β2‐m and possibly inhibit the aggregation process is still largely unexplored mainly because the protein lacks a specific active site. Based on our previous findings, we selected a pilot set of sulfonated molecules that are known to either bind or not to the protein, including binders that are anti‐amyloidogenic. We show how a complementary approach, using high‐resolution mass spectrometry and in silico studies, can offer rapid and precise information on affinity, as well as insight into the structural requisites that favour or disfavour the inhibitory activity. Overall, this approach can be used for predictive purposes and for a rapid screening of fibrillogenesis inhibitors.
Synthesis, 3D‐QSAR, and Structural Modeling of Benzolactam Derivatives with Binding Affinity for the D2and D3Receptors
Authors: López Laura , Selent Jana , Ortega Raquel , Masaguer Christian F. , Domínguez Eduardo , Areias Filipe , Brea José , Loza María Isabel , Sanz Ferran , Pastor Manuel
Published: June 2010

A series of 37 benzolactam derivatives were synthesized, and their respective affinities for the dopamine D2and D3receptors evaluated. The relationships between structures and binding affinities were investigated using both ligand‐based (3D‐QSAR) and receptor‐based methods. The results revealed the importance of diverse structural features in explaining the differences in the observed affinities, such as the location of the benzolactam carbonyl oxygen, or the overall length of the compounds. The optimal values for such ligand properties are slightly different for the D2and D3receptors, even though the binding sites present a very high degree of homology. We explain these differences by the presence of a hydrogen bond network in the D2receptor which is absent in the D3receptor and limits the dimensions of the binding pocket, causing residues in helix 7 to become less accessible. The implications of these results for the design of more potent and selective benzolactam derivatives are presented and discussed.
Off‐Target Effects Related to the Phosphorothioate Modification of Nucleic Acids
Authors: Winkler Johannes , Stessl Martina , Amartey Jennifer , Noe Christian R.
Published: June 2010

Phosphorothioate antisense oligonucleotides have been widely used in clinical studies for rational sequence‐specific gene silencing. However, several sequence‐unspecific off‐target effects have been recently described for this compound class. In contrast to siRNA‐mediated knockdown of the same gene, the bcl‐2‐targeted oblimersen (Genasense, G3139) downregulates a number of proteins involved in apoptotic resistance and several glycolytic enzymes in 607B human melanoma cells. Regardless of their target, phosphorothioate‐modified antisense and siRNA compounds, but not oligonucleotides with a phosphodiester backbone, resulted in a similar impact on the proteome. Unspecifically downregulated proteins include cancer markers involved in apoptotic resistance and endoplasmatic reticulum (ER) stress such as the 78 kDa glucose regulated protein (GRP 78), protein disulfide isomerase A3 (PDIA3, GRP 58), calumenin, and galectin‐1, as well as the glycolytic enzymes triose phosphate isomerase, glyceraldehyde phosphodehydrogenase, and phosphoglycerate mutase. The depletion of the glycolytic enzymes is reflected by a decrease in L‐lactate production, indicating a partial reversal of the Warburg effect. Compared with other phosphorothioate oligonucleotides, oblimersen generally led to a more pronounced effect both in terms of the number of influenced proteins and the extent of downregulation, suggesting a synergistic effect of Bcl‐2 downregulation.
Neighborhood socioeconomic status and behavioral pathways to risks of colon and rectal cancer in women
Authors: Kim Daniel , Masyn Katherine E. , Kawachi Ichiro , Laden Francine , Colditz Graham A.
Published: June 2010

BACKGROUND:

Neighborhood amenities and resources plausibly determine individual modifiable risk factors for colon and rectal cancer. Evidence on the associations between neighborhood socioeconomic status (SES) and incident colon and rectal cancer is limited.

METHODS:

The authors analyzed a prospective cohort of 111,129 women in the Nurses' Health Study with no history of cancer in 1986 followed to 2006. Neighborhood SES was based on Census‐derived characteristics of block groups of residence. Cox models were used to estimate the multivariate‐adjusted associations between neighborhood SES and incident colon and rectal cancer, and to examine for effect modification. For significant associations, path models were estimated with behavioral risk factors included as potential mediators.

RESULTS:

Neighborhood SES was unassociated with colon cancer among all women. However, among women with college or greater education, higher neighborhood SES was inversely related to colon cancer (P for trend = .01; P for interaction between neighborhood SES and education = .03). Path analysis suggested mediation by red meat intakes and body mass index (BMI). Higher neighborhood SES was inversely related to rectal cancer among all women (relative risk in highest quintile, 0.64; 95% confidence interval, 0.44‐0.93; P for trend = .08). Path analysis was consistent with mediation by multivitamin use and BMI.

CONCLUSIONS:

These findings suggest that living in a higher‐SES neighborhood may protect against rectal cancer in women and colon cancer in higher‐educated women, mediated by selected behavioral risk factors. Risk factor differences between colon and rectal cancer may account for discrepancies in estimated neighborhood effects by cancer site. Cancer 2010. © 2010 American Cancer Society.
Forgoing medical care because of cost
Authors: Weaver Kathryn E. , Rowland Julia H. , Bellizzi Keith M. , Aziz Noreen M.
Published: June 2010

BACKGROUND:

Many US cancer survivors live years after diagnosis, which emphasizes the importance of healthcare access for survivors. It is not known whether having cancer has an impact on disparities in healthcare access that are present in the general population. The objective of this study was to examine the prevalence of forgoing care because of financial concerns in a representative sample of US adults to determine whether cancer history and race/ethnicity are associated with the likelihood of forgoing medical care.

METHODS:

Data from the US National Health Interview Survey (NHIS) from 2003 to 2006 were used to identify 6602 adult cancer survivors and 104,364 individuals who had no history of cancer. Self‐reports of forgoing medical care services because of cost were analyzed according to cancer history and race/ethnicity using multivariate logistic regression.

RESULTS:

The prevalence of forgoing care because of cost among cancer survivors was 7.8% for medical care, 9.9% for prescription medications, 11.3% for dental care, and 2.7% for mental healthcare. Cancer survivors aged <65 years were more likely to delay or forgo all types of medical care compared with adults who did not have a history of cancer. Hispanic and black cancer survivors were more likely to forgo prescription medications and dental care than white survivors. Disparities among cancer survivors largely were reflective of those in the general adult population.

CONCLUSIONS:

More than 2 million US cancer survivors did not get 1 or more needed medical services because of financial concerns during the studied period. Future research needs to examine the impact of forgoing care on survivors' quality of life and survival. Cancer 2010. Published 2010 by the American Cancer Society.
Microwave dielectric properties of (1‐x)La(Mg0.5Sn0.5)O3‐x(Sr0.8Ca0.2)3Ti2O7 ceramic system with a near zero temperature coefficient of resonant frequency
Authors: Chen Yih‐Chien , Wang Yen‐Nien , Chen Kai‐Hao
Published: June 2010

In this study, the microwave dielectric properties of (1‐x)La(Mg0.5Sn0.5)O3‐x(Sr0.8Ca0.2)3Ti2O7 ceramic system prepared by the conventional solid‐state method have been investigated for application in mobile communication. It was found that the diffraction peaks of (1‐x)La(Mg0.5Sn0.5)O3‐x(Sr0.8Ca0.2)3Ti2O7 ceramic system shift to higher angles as x increases from 0.2 to 0.4. It was also found that the X‐ray diffraction patterns of the 0.8La(Mg0.5Sn0.5)O3‐0.2(Sr0.8Ca0.2)3Ti2O7 ceramics exhibited no significant phase difference at different sintering temperatures. The average grain size of the (1‐x)La(Mg0.5Sn0.5)O3‐x(Sr0.8Ca0.2)3Ti2O7 ceramic system decreased from 6.4 to 4.3 μm as the value of x increased from 0.2 to 0.4 sintered at 1550 °C for 4 h. The dielectric constant increased from 26.6 to 35.9 and the quality factor (Q×f) decreased from 31,600 to 23,300 GHz for (1‐x)La(Mg0.5Sn0.5)O3‐x(Sr0.8Ca0.2)3Ti2O7 ceramic system as the x value increases from 0.2 to 0.4 sintered at 1550 °C for 4 h. The average value of temperature coefficient of resonant frequency (τf) increased from ‐18 to +8 ppm/ K as the x value increases from 0.2 to 0.4. (© 2010 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Crystal structure of caesium hydrogen (L)‐aspartate and an overview of crystalline compounds of aspartic acid with inorganic constituents
Authors: Fleck M. , Emmerich R. , Bohatý L.
Published: June 2010

The crystal structure of the new polar compound caesium hydrogen (L)‐aspartate, Cs(C4H6NO4), (abbreviated: Cs(L ‐AspH)) was determined from single crystal X‐ray diffraction data; it comprises two crystallographically different L ‐AspH anions that are connected via caesium cations to form a three dimensional framework. The Cs ions are irregularly sevenfold [Cs1O7] respectively eightfold [Cs2O8] coordinated to all α– and β– carboxylate oxygen atoms. Cs(L ‐AspH) represents a novel structure type of its own, as do most compounds of (L)‐aspartic acid with inorganic constituents. A brief summary of such structurally known aspartates is given. (© 2010 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Synthesis of anisotropic gold nanoparticles using xylitol as a dual functional reductant and stabilizer
Authors: Zhu Jinmiao , Yao Chengli , Yuan Xinsong , Chen Chen , Qi Chunxia , Xia Yuehua , Dong Lin
Published: June 2010

The morphology of gold nanoparticles was controlled with hydrogentetrachloroaurate (HAuCl4) and xylitol through a hydrothermal process using xylitol as reducing agent and controlled reagent. The molar ratio of xylitol relative to HAuCl4, reaction time and temperature played important roles in determining the geometric shape and size of the product. These nanoplates were single crystals with planar width of 80‐500 nm. The formation of nanobelts and two‐dimensional single‐crystal nanosheets is explained by the preferential adsorption of xylitol molecules from the solution onto the {111} planes of Au nuclei. These nanosheets could be used, for example, in gas sensors, in the fabrication of nanodevices and substrate materials, in property studies, and also for inducing hypothermia in tumors. (© 2010 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)