bluuebunny/crossref_metadata_2025 huggingface dataset:
Association between vitamin D level and patients with cholestasis
Authors: Anwar Manal M. , Arafa Ahmed E. , Morgan Dalia S. , Mohamed Khaled K.
Published: April 2018

Background: Estimate the prevalence of vitamin D deficiency among patients diagnosed with chronic cholestasis and investigates the association between their clinical manifestations and lab results of 25(OH) D levels.Methods: A cross sectional study of 50 patients aged > 3 months up to 18 years, who had medical care in the Beni-Suef University hospital, Beni-Suef governorate, Egypt. All patients were fully investigated including routine labs in addition to 25- [OH] D levels and dual energy X-ray absorptiometry (DXA).Results: Mean age was 6.5±4.5 years. Mean serum 25 (OH) D levels was 37.9±28.2; 30% of patients had 25 (OH) D <20 ng/ml and 26% had 25 (OH) D 20-<30 ng/ml. Low BMD was diagnosed in 73.1% of patients. The spine DXA BMD ranged between -5.4 and -1.4 (-2.9±0.9 Z-scores). A delayed milestone was reported in 32% of patients, and 56% had signs of rickets.Conclusions: Deficiency of Vitamin D, signs of rickets and osteoporosis were evident in chronic cholestasis patients. No statistical significance was detected between 25- D [OH] levels and clinical, laboratory and radiological findings.
Medication adherence among hypertensive adults residing in a rural area of Dakshina Kannada district
Authors: Kumar Ananta , R. Pracheth
Published: April 2018

Background: Medication adherence is regarded as a critical determinant of control of hypertension. The objective of the study was to determine the prevalence and factors associated with medication adherence among hypertensive adults, residing in a rural area of Dakshina Kannada district.Methods: A cross-sectional study was conducted from August to November 2015. A pre-designed, pre-tested proforma was used to collect information. The study participants were enquired about the medication adherence using the Morisky medication adherence scale (MMAS-8). Medication adherence was graded as high (zero score), medium (1-2 score) and low (3-8 score).Results: A total of 193 hypertensive adults fulfilling the inclusion criteria were included. Low medication adherence was observed in 56 (29.01%) of the study participants. Majority (67.88%), had medium adherence, while a very low percentage (3.11%) had high medication adherence, as per the MMAS-8. Low adherence was found to be higher among participants belonging to low socio-economic status (39.44%) when compared to other classes. This association was statistically significant (p=0.0025). Those having diabetes had higher rates of poor adherence (66.67%) when compared to non-diabetics (13.24%), which was statistically significant (p<0.0001). Consuming ≥3 medications was another factor found to be significantly associated with low medication adherence (p<0.0001).Conclusions: We conclude that 29.01% of the study participants had low medication adherence. Low socio-economic status (Class IV+V), presence of diabetes mellitus and number of medications were the factors found to be significantly associated with low medication adherence.
Awareness of risk of infections to health care professionals and its preventive practices among medical students: a cross-sectional study
Authors: Savanthe Aruna Marati , Savolu Cynthia Subhaprada
Published: April 2018

Background: Occupational health is a neglected public health issue among healthcare workers in developing countries leading to health care associated infections both to patients and medical students unless infection prevention and control (IPC) measures followed. This study was conducted with an aim to assess the degree of knowledge regarding infection in health care professionals and infection control measures among medical students.Methods: A cross-sectional study was conducted from June 1 to July 31, 2017 on 95 students in the MBBS final year Part I at Kurnool Medical College Kurnool by simple random sampling technique after taking informed consent. A semi structured questionnaire with information regarding their knowledge on risk of infection and infection prevention practices was used. Using SPSS ver. 20, data analysed in proportions and means.Results: Mean age of the study participants was 20.29±0.756 years, 83.2% (n=79) students expressed tuberculosis followed by Hepatitis B infection as the most common infection the medical students are exposed to. 97.9% definitely knew that they contact infections if standard precautions are not followed. Only 51.6% students were aware of all steps of hand wash. 83.2% were already vaccinated to hepatitis B and among vaccinated 73.4% had completed the course fully.Conclusions: Effective infection prevention measures are pivotal in providing high quality health care for patients and a safe working environment for those that work in healthcare settings. Hence infection prevention and control guidelines particularly standard precautions should be incorporated into the curriculum before entering clinical postings.
Community based descriptive study on assessment of nutritional status among preschool children Pullipakkam village, Tamil Nadu
Authors: H. Gladius Jennifer , P. A. Archana Lakshmi
Published: April 2018

Background: Nutrition assessment is to obtain precise information on the prevalence of nutritional problems and identification of individuals at risk. 25.7% of Indian children under five years were underweight and 28.6% were stunted due to chronic under nutrition, India accounts for more than 3 out of 10 stunted children in the world. Under nutrition is substantially higher in rural areas. Hence, this study conducted. The objective of the study was to assess the nutritional status of preschool children (1-5 years) in Pullipakkam, field practice area of KIMSRC.Methods: An observational study conducted in Pullipakkam from January 2017 to February 2017. 75 children aged 1–5 years were selected by simple random sampling. After getting informed consent from parents, Data were collected using structured questionnaire by interview method. Chi square test at 5% α were calculated by using SPSS 20V.Results: Among 75 children, stunting (52.8%), wasting (62.3%), mid arm circumference less for age (13.3%). 73% had inadequate calories intake. There was no significant association (p>0.05).Conclusions: The nutritional status of the children usually remains under question. Parents have to be properly health educated on balanced diet with locally available low cost foods has to given.
Health related quality of life in COPD patients: a cross-sectional study
Authors: Gaude Nilam C. , Desai Archana M.
Published: April 2018

Background: Chronic obstructive pulmonary disease (COPD) is a progressive lung disease that causes breathlessness (initially with exertion) and predisposes to exacerbations and serious illness. COPD is not curable, improvement of quality of life of such patients is thus of importance. The aims and objective of the study was to assess health related quality of life and its determinants in patients with COPD.Methods: Cases were first identified from the medical records of Department of RHTC, Mandur. Eligible cases were then interviewed by home visits. Health Related Quality of Life (HRQL) of participants was assessed using St. George’s Respiratory Questionnaire (SGRQ). ANOVA, student’s t test and correlation were used to interpret the data.Results: This study shows an impaired quality of life in COPD patients. Quality of life was impaired in all the domains. However, activity domain was the most affected while impact domain was least affected. Age, sex, smoking, BMI, socioeconomic status, occupation did not impact quality of life in significant manner.Conclusions: This study shows an impaired quality of life in COPD patients. As COPD is slowly progressing disease with no specific cure, we should focus more on treatable aspects of quality of life.
SWOT analysis of IEC implementation in RMNCH+A program in Udupi district
Authors: Dhange Vijay , Sumit Kumar , Pattanshetty Sanjay M.
Published: April 2018

Background: Information education and communication (IEC) activities in “Reproductive, maternal, newborn, child, and adolescent health programme” (RMNCH+A) plays an important role in creating awareness in the community about the key domains of reproductive and child health. The main purpose of the IEC activities is to bring about changes in knowledge, attitude, belief and behavior of the community towards healthcare.Methods: A qualitative cross-sectional study was conducted among the stakeholders involved in the IEC activities of RMNCH+A programme in Udupi district, Karnataka. In-depth interviews were conducted among the Medical officers, Accredited social health activist (ASHAs) Auxiliary nurse midwifes (ANMs) and lady health visitors (LHV) in the health facilities of Udupi District. Thematic analysis was used for data analysis.Results: Mobilizing the community members and local logistics management at the field level are the main barriers identified in the implementation of IEC activities.Conclusions: It is necessary to leverage and comprehend the strengths of the IEC programs, improvise on the weaknesses, explore the opportunities and minimize the threats associated with the IEC activities under RMNCH+A program.
Pomiar zachowań zdrowotnych w okresie późnej dorosłości – Kwestionariusz Zachowań Zdrowotnych dla Seniorów
Authors: Zadworna-Cieślak Magdalena
Published: April 2018

The current demographic processes invite an analysis of the lifestyle of people in late adulthood and its determinants. A thorough diagnosis of senior health is also needed, not only for the purposes of description and explanation, but also – above all – for the creation of health programs. The present study analyses the specificity of health behavior of people of senior age. It describes the Health-Related Behavior Questionnaire for Seniors (KZZ-S), a tool used to measure the health behaviors of seniors (i.e., people aged 60 and above), and presents its theoretical basis. The questionnaire has a five-factor structure, as revealed by exploratory and confirmatory factor analysis. It consists of 24 items and allows the calculation of the overall rate of such health behaviors and behavioral categories as positive attitude to life, behavior related to physical health, attention to mental condition, behavior associated with prevention and treatment, and environmental behavior. A higher score indicates a higher level of behavior beneficial to health. In total, the participants in the study were 522 people diverse in terms of activity and life situation, and the aim was to determine the psychometric properties of the KZZ-S. The KZZ-S is a reliable and valid measure with satisfactory psychometric properties (Cronbach’s α was .87 for the whole test and ranged from .63 to .79 for its subscales; absolute stability determined by test-retest was .88).
Democracy evaluation and its selected determinants in the context of the 2014 local elections in Poland
Authors: Klamut Ryszard , Kantor Agata
Published: April 2018

The local elections that were held in November 2014 stirred up considerable controversy in Po-land. The article is an attempt to describe how Poles evaluated the overall functioning of democ-racy in the context of these elections and what determinants significantly contributed to that evaluation. We examined three levels of democracy evaluation: general beliefs (Jost’s system justification), the current state of democracy (Dahl’s democratic institutions), and specific events connected with the functioning of the democratic system (the quality of the elections and the level of trust in the elected representatives). We also tested the extent to which these levels of democracy evaluation were explained by sociopolitical determinants, such as the general level of trust in people, patriotism and nationalism, or the experience of security. The study was conducted shortly after the second round of the election on a sample of 524 subjects. The obtained results show a low quality of democracy (particularly on the level of general beliefs and trust in the newly elected authorities) and reveal associations between aspects of evaluation and the investigated determinants.
Extrato aquoso de bulbos de tiririca sobre a germinação e crescimento inicial de plântulas de rabanete
Authors: Cavalcante Jerffeson Araujo , Lopes Kilson Pinheiro , Pereira Natali Almeida Evangelista , Silva Joseano Graciliano , Pinheiro Romário Mesquita , Marques Robson Luiz Legorio
Published: April 2018

Objetivou-se avaliar o efeito de diferentes concentrações do extrato aquoso de bulbos de tiririca (Cyperus rotundus L.) em comparação ao ácido indol-3-butírico (AIB) sobre a germinação e desenvolvimento inicial de plântulas de rabanete. Foram conduzidos dois experimentos, em ambos empregando-se o delineamento inteiramente casualizado com quatro repetições de 50 sementes para germinação e 20 sementes para comprimento da raiz primária. No experimento I, as sementes de rabanete foram submetidas às concentrações de zero, 0,5, 1,0 e 1,5 mg L-1 de AIB. No experimento II, as sementes da espécie estudada foram submetidas às concentrações de zero, 15, 25, 50 e 100% do extrato aquoso de bulbos de tiririca, confrontadas com a melhor concentração obtida da auxina sintética. Em ambos experimentos, as sementes foram embebidas em cada uma das soluções por cinco minutos. Para avaliar o efeito dos tratamentos, foi realizado o teste de germinação, primeira contagem de germinação, índice de velocidade de germinação e comprimento de radícula. Os dados obtidos foram submetidos a análise de variância e as médias comparadas pelo teste de Tukey a 5% de probabilidade para o fator qualitativo e regressão polinomial para o fator quantitativo. O AIB possibilitou melhor desempenho fisiológico de sementes de rabanete, sendo 1,5 mg L-1 a melhor concentração empregada. O extrato aquoso de tiririca estimula a germinação e o desenvolvimento inicial de plântulas de rabanete quando suas sementes são embebidas com concentrações em torno de 25%, assemelhando-se aos resultados obtidos quando do emprego do AIB.
O OLHAR DO PEDAGOGO PARA O DESENHO NA EDUCAÇÃO INFANTIL
Authors: Spilere Aline Dagostin , Camargo Gislene
Published: April 2018

: Este artigo objetivou analisar como o pedagogo compreende o desenho na Educação Infantil, investigando as ações pedagógicas desenvolvidas em relação aos desenhos das crianças de 5 e 6 anos. O problema que desencadeou a pesquisa foi: Quais as intencionalidades pedagógicas desenvolvidas em relação ao desenho das crianças de 5 e 6 anos na Educação Infantil? Esta pesquisa se caracterizou como qualitativa, levando em consideração as singularidades dos pesquisados, utilizando como instrumento de coleta de dados, a observação.  As observações foram realizadas em uma escola da Rede Municipal de Criciúma – SC, analisando a atuação dos (as) pedagogos(as) frente ao desenho infantil. Teve como fonte teórica, os documentos: BRASIL (1998); BRASIL (2010); juntamente com autores Derdyk (2015); Sans (2007); Oliveira (1999); Gil (2002) e Zanelli (2002) que foram fundamentais para as análises teóricas desta pesquisa. Considerou-se que as intencionalidades pedagógicas sobre o desenho das crianças da pré-escola, não foram manifestadas de maneira como propõem os RCNEI e DCNEI, constatando-se que as pedagogas necessitam de maior aprofundamento na área. Entende-se que o desenho na Educação Infantil proporciona a criatividade, expressão, desenvolvimento, aprendizado, representações de suas vivências, entre outros, o que suscita das pedagogas explorar melhor essa linguagem e redimensionar seus olhares sobre os desenhos das crianças.PALAVRAS CHAVE: Desenho. Educação Infantil. Pedagogos(as). Formação de professores.
ESCOLA E TECNOLOGIAS: ANÁLISE DAS PRÁTICAS EDUCATIVAS DOS PROFESSORES NOS ANOS INICIAIS DA REDE PÚBLICA DE MARACAJÁ-SC
Authors: Silva Bruna da , Giacomazzo Graziela Fátima
Published: April 2018

Este trabalho buscou analisar e discutir as práticas desenvolvidas pelos professores que utilizam Tecnologia da Informação e Comunicação (TIC), nos anos iniciais do Município de Maracajá- SC. Esse foi o objetivo geral da pesquisa que teve como objetivos específicos: identificar os recursos tecnológicos utilizados pelos professores nas suas práticas em sala de aula; compreender qual a importância da tecnologia no processo de ensino aprendizagem na percepção dos professores; verificar quais as dificuldades encontradas pelos professores na utilização das tecnologias nas práticas pedagógicas; verificar se os professores estão preparados para fazer uso das TIC em suas práticas. Caracteriza-se como pesquisa qualitativa, sendo que a análise dos dados, a partir do referencial teórico, contemplou autores que discutem educação e tecnologias. A pesquisa por meio de um questionário foi realizada com 08 (oito) professores dos anos iniciais da rede pública de Maracajá. Os dados coletados foram organizados em quatro tópicos e analisados a partir do referencial teórico. Os resultados obtidos revelaram que os professores dos anos iniciais da rede pública municipal de Maracajá reconhecem e vivenciam a importância das TIC em suas práticas educativas. Entretanto, também ficou evidente que lidam com os desafios, desde a escassez de recursos tecnológicos até a falta de formação dos professores na área da tecnologia. PALAVRAS CHAVE: Tecnologias. Escola. Práticas Educativas. Professores.
On Theses Without Iterated Modalities of Modal Logics Between C1 and S5. Part 1
Authors: Pietruszczak Andrzej
Published: April 2018

This is the first, out of two papers, in which we identify all logics between C1 and S5 having the same theses without iterated modalities. All these logics canbe divided into certain groups. Each such group depends only on which of thefollowing formulas are theses of all logics from this group: (N), (T), (D), ⌜(T)∨ ☐q⌝,and for any n > 0 a formula ⌜(T) ∨ (altn)⌝, where (T) has not the atom ‘q’, and(T) and (altn) have no common atom. We generalize Pollack’s result from [12],where he proved that all modal logics between S1 and S5 have the same theseswhich does not involve iterated modalities (i.e., the same first-degree theses).
Mieszkanie dla seniora – formy budownictwa senioralnego oraz stan ich rozwoju w Polsce
Authors: Dudek-Mańkowska Sylwia
Published: April 2018

W artykule omówiono nowe formy budownictwa dla seniorów (tj. dom międzypokoleniowy, mieszkanie wspomagane, osiedle z ograniczeniem wiekowym, cohousing senioralny, wielofunkcyjne zespoły mieszkaniowe dla seniorów) oraz ich dostępność w Polsce.
Czynniki kształtujące warunki życia w Piotrkowie Trybunalskim po transformacji ustrojowej
Authors: Nowak Sylwia
Published: April 2018

W artykule przedstawiono diagnozę warunków życia w Piotrkowie oraz czynników na nie oddziałujących w kontekście konsekwencji transformacji ustrojowej Polski w oparciu o dostępne materiały źródłowe, jak i własne badania. Decydujące oddziaływanie na poziom zadowolenia mieszkańców z własnego środowiska zamieszkania ma w świetle wyników pracy estetyka zabudowy. Szczególnie ważne jest dla nich ponadto rozmieszczenie w najbliższej okolicy obiektów usług społecznych: podstawowej opieki zdrowotnej oraz bibliotek.
Sinonimia en locuciones léxicas del español mexicano
Authors: Fajardo Rojas Carmen Teresa
Published: April 2018

La sinonimia en las locuciones ha sido un tema ligado estrechamente a la variación fraseológica, sin embargo, existe una diferencia entre ambos fenómenos. ¿Cuáles son los criterios lingüísticos que nos permiten determinar que dos o más locuciones léxicas son unidades sinonímicas y no variantes? Para contestar esta interrogante he decidido analizar veintitrés locuciones del español de México a través de una serie de criterios lingüísticos, desprendidos del análisis de varias posturas teóricas fraseológicas, con el fin de esclarecer la diferencia entre estas relaciones. Los resultados sugieren que son necesarias cuatro condiciones para considerar sinónimas dos locuciones léxicas: ser semejantes en significado, pertenecer a una misma categoría gramatical, poseer estructura sintáctica distinta y ser intercambiables en sus contextos de uso sin alterar el significado global del enunciado.
Similitud y contraste en el procesamiento léxico: Aproximación teórico-práctica
Authors: Varo Varo Carmen
Published: April 2018

En el presente trabajo nuestro objetivo es valorar la función que los rasgos de similitud y contraste desempeñan en los modelos cognitivos actuales del procesamiento lingüístico. De acuerdo con tal propósito, nos detenemos en las implicaciones de estos en la representación del conocimiento léxico y su relevancia para la caracterización de las relaciones semánticas. Por otra parte, presentamos varias evidencias científicas y algunos datos experimentales a favor de la eficiencia del principio de contraste que nos permiten cuestionar las propuestas mayoritarias elaboradas hasta el momento.
Olweus öğrenciler için akran zorbalığı anketinin Türkçeye ve Türkiye’ye uyarlanması ve geçerlilik, güvenirlik analizi
Authors: TIPIRDAMAZ SİPAHİ Hilal , KARABABA Ali Osman
Published: April 2018

Amaç: Bu çalışmada, Olweus
öğrenciler için akran zorbalığı (OÖAZ) anketinin Türkçe formunun geçerlilik ve
güvenirliğinin incelenmesi amaçlandı. 

Gereç ve Yöntem: İlk aşamada anket
Türkçeye çevrildi. Araştırmacılar ve çevirmenler tarafından ortak formun
oluşturulmasından sonra, form iki ana dili olan bir çevirmen tarafından
İngilizceye çevrildi. Anket geçerlilik çalışması sırasında yüzey ve kapsam
geçerliliği açısından uzman panelinde değerlendirildi ve gerekli görülen
değişiklikler yapıldı. Pilot çalışmanın ardından, anket İzmir ili Bornova
ilçesi Milli Eğitim Müdürlüğü’ne bağlı ilköğretim okulları altıncı ve yedinci
sınıflarını temsil eden 405 öğrenciye uygulandı (%95 G.A., %7.6 prevalans ve
%2.5 hata payı). Anketin güvenirliği Cronbach Alfa ve iki yarım test (Split Half) yöntemleriyle
değerlendirildi.

Bulgular: Uzman paneli anketin
kavramsal yapıyı karşıladığı ve literatüre uygun biçimde akran zorbalığının
temel alanlarını içerdiği görüşünde birleşti. Geçerlilik ve güvenirlik
çalışması 2008 yılı Nisan ayında Bornova’da sekiz ilköğretim okulundaki 6. ve
7. sınıflarda gerçekleştirildi. Araştırmaya katılan 405 öğrenciden OÖAZ
anketini dolduran 400 öğrenci veri tabanına alındı. Anketin tümünün Cronbach
Alfa değeri .81’di. Tek, çift sıralaması içinde Spearman-Brown iki yarım test
güvenirlik katsayısı .85 olarak bulundu.

Sonuç: Çalışmanın bulguları,
Olweus öğrenciler için akran zorbalığı anketinin Türkçe versiyonunun geçerlilik
ve güvenirliğinin tatmin edici olduğunu göstermektedir. Anket akran zorbalığı
araştırmalarında faydalı bir araç olarak kullanılabilir.
Comparison of pain score and patient satisfaction between laparoscopic and open abdominal incisional hernia repair
Authors: ARER İlker Murat , KUŞ Murat , AKKAPULU Nezih , YABANOĞLU Hakan , AYTAC Hüseyin Özgür , TÖRER Nurkan
Published: April 2018

Aim: Incisional hernia is one of the most common postoperative complications of abdominal surgery. Recently laparoscopic repair was introduced. The aim of this study is to compare pain scores and satisfaction rates of patients performed open and laparoscopic incisional hernia repair.Materials and Methods: A total of 164 patients were included. Group 1 (n=47) consists of patients performed laparoscopic repair and Group 2 (n=117) consists of open repair. Patients were analyzed according to demographic data, operative findings, postoperative complications and recurrence. 32 (68.08%) patients in Group 1 and 88 (75.21%) patients in Group 2 were applied to telephone survey. Pain scores and satisfaction rates of patients were compared.Results: 51 (31.1%) patients were male and 113 (68.9%) patients were female. Mean age of patients was 55.35±11.73 years. Postoperative complications were found in only 2.1% of patients in Group 1 and 23.9% of patients in Group 2 (p<0.05). Recurrence rates for Group 1 and 2 was 25.7% and 20%, respectively (p>0.05). No statistical difference was observed between groups regarding to pain scores and satisfaction rates (p>0.05).Conclusion: Although laparoscopic repair seems to have advantages, it has no superiority to the open repair regarding pain and satisfaction.
Çölyak hastalığı'nda teşhis süresi
Authors: KARAAHMET Fatih
Published: April 2018

Amaç: Çölyak hastalığı
(gluten duyarlı enteropati), genetik olarak duyarlı kişilerde buğday, arpa,
çavdar ve yulafın içinde bulunan glutene karşı oluşan duyarlılık reaksiyonudur.
Çölyak hastalığında klinik oldukça farklı ve değişken olabilir. Atipik
belirtilerden ötürü çoğu kez tanının akla getirilmemesi nedeniyle başka
hastalıklar düşünülerek gereksiz ve sonuç getirmeyecek araştırmalar, tedaviler
yapılır. Bu çalışmadaki amaç Çölyak Hastalığının belirtilerinin başlangıcından
teşhis konulmasına kadar geçen zamanı belirlemektir.

Gereç ve
Yöntemler: Ankara
Eğitim ve Araştırma Hastanesi Gastroenetroloji polikliniğine başvuran, yaş
sınırı gözetmeksizin toplam 113 Çölyak hastası çalışmaya alındı. Hastalarda
tanı zamanı, tanı öncesi ilk belirtilerin başladığı tarih, belirtiler ve
belirtiler ile tanı arasındaki süre sorgulandı.

Bulgular:
Hastaların
yaş ortalaması 36.83±14.59, belirti başlangıcından tanı anına kadar geçen süre
ortalaması 29.1±57.11 aydı. Erkeklerde tanı için geçen ortalama süre
22.13±36.75 ay iken kadınlarda 32.36±64.54 ay olarak saptandı.

Sonuç: Çölyak Hastalığı
belirti başlangıcından tanı anına kadar geçen süre ortalaması 2.5 yıl olup, erken
ve doğru klinik tanı maddi kazanç yanında gereksiz zaman ve çaba harcanmasını
da engelleyecektir.
Skin necrosis: An uncommon side effect of warfarin therapy
Authors: DEVRİM Tuba , DEMİRKAN Serkan
Published: April 2018

Warfarin
is commonly used in the treatment and prevention of thromboembolic events.
However, it is known to undesirably cause hypercoagulable conditions, including
warfarin-induced skin necrosis (WISN). This report describes a 70-year-old man presented with an
extensive WISN while an inpatient for treatment of a left deep femoral
vein thrombosis. He had a background
of colon adenocarcinoma and multiple metastatic foci in the liver.
ESKİ ANADOLU TÜRKÇESİ İLE YAZILMIŞ AHVĀL-İ MEVT ADLI ESER ÜZERİNDE BİR DİL İNCELEMESİ
Authors: YAMAN Ümran
Published: April 2018

Bu
makalede, Mahmûd isimli bir şair tarafından Eski Anadolu Türkçesi ile yazılmış,
konu bakımından birbirinden farklı toplam beş manzume üzerinde bir çalışma
gerçekleştirilmiştir. Giriş kısmında manzumelerin bulunduğu yazmanın tavsifi
yapılmış, ardından dil ve üslup özellikleri hakkında genel bir değerlendirmeye
yer verilmiştir. Daha sonra manzumeler dilbilgisi bakımından bir incelemeye
tâbi tutulmuş ve metin transkripsiyonlu olarak Latin harflerine aktarılmıştır.
Makalenin sonuna metnin tıpkıbasımı eklenmiştir.
Dentoalveolar changes in post-twin block appliance orthodontic treatment class II dentoskeletal malocclusion
Authors: Yoana Y , Chemiawan Eka , Setiawan Arlette Suzy
Published: April 2018

Background: The analysis of cephalometric radiographs provides information about facial skeletal structures, jaw bone-base relationships, incisive-axial inclination relationships, soft tissue morphology, growth direction and pattern, malocclusion classification and the limitations of orthodontic treatments. In class II malocclusion, the mesiobuccal cusp of the permanent maxillary first molar rests between the first mandibular molar and the second premolar. A twin block appliance is recommended to treat Class II dentoskeletal malocclusion with retrognathic mandible characteristics. Purpose: The aim of this study was to analyze the dentoalveolar alterations in class II dentoskeletal malocclusion with retrognathic mandible characteristics after orthodontic treatment with twin block appliance based on a Steiner analysis. Methods: This research constitutes a retrospective study using secondary data derived from the lateral cephalometric radiographs of patients with Class II malocclusion treated with twin block appliance at the Pediatric Dentistry Department of the Oral and Dental Hospital, Universitas Padjajaran, Bandung. The data was analyzed using a T-test for normally distributed paired data. In cases where data was not normally distributed, a Wilcoxon test was employed. Results: The average measurements showed statistically significant dentoalveolar changes among class II malocclusion patients after twin block appliance treatment when analyzed using the paired t-test based on Steiner method cephalometric radiograph analysis (p < 0.05). Conclusion: It is concluded that a twin block appliance is effective in treating class II dentoskeletal malocclusion with a retrognathic mandible based on dentoalveolar changes resulting from Steiner analysis.
Lambertianic Acid Sensitizes Non-Small Cell Lung Cancers to TRAIL-Induced Apoptosis Via Inhibition of XIAP/NF-kB and Activation of Caspases and Death Receptor 4
Authors: Ahn Deoksoo , Lee HyoJung , Hwang Jisung , Han Hyukgyu , Shim BumSang , Kim Sunghoon
Published: April 2018

Lambertianic acid (LA) is a biologically active compound from the leaves of Pinus koraiensis. In the present study, apoptotic mechanisms of LA plus TNF-related apoptosis-inducing ligand (TRAIL) were elucidated in non-small cell lung cancer cells (NSCLCs). Cytotoxicity assay, flow cytometry, immunoprecipitation and Western blotting were performed. Here, combined treatment of LA and TRAIL increased cytotoxicity, sub-G1 population and cleaved poly (ADP-ribose) polymerase (PARP) and caspase3/8/9 in A549 and H1299 cells compared to LA or TRAIL alone. Furthermore, combined treatment of LA and TRAIL significantly decreased anti-apoptotic proteins such as B-cell lymphoma 2 (Bcl-2), Fas-like inhibitor protein (FLIP) and X-linked inhibitor of apoptosis protein (XIAP) and enhanced the activation of pro-apoptotic proteins Bid compared to LA or TRAIL alone. In addition, combined treatment of LA and TRAIL upregulated the expression of Death receptor 4 (DR4) and downregulated phosphorylation of nuclear factor kappa-light-chain-enhancer of activated B cells (p-NF-B), inhibitory protein of kB family (p-IB) and FLIP in A549 and H1299 cells along with disrupted binding of XIAP with caspase3 or NF-B. Overall, these findings suggest that lambertianic acid enhances TRAIL-induced apoptosis via inhibition of XIAP/NF-B in TRAIL resistant NSCLCs.
Five-Year Clinical Outcomes of Trabectome Surgery at a Single Glaucoma Center
Authors: Esfandiari Hamed , Shah Priyal , Torkian Pooya , Conner Ian P. , Schuman Joel S. , Hassanpour Kiana , Loewen Nils A.
Published: April 2018

Purpose: To analyze the five-year results of Trabectome ab interno trabeculectomy of a single glaucoma center. Method: In this retrospective interventional single-center case series, data of 93 patients undergoing ab interno trabeculotomy between September 2010, and December 2012 were included. Kaplan-Meier analysis was performed using success criteria defined as postoperative intraocular pressure (IOP) ≤21 mm Hg, or >20% reduction from preoperative IOP, and no need for further glaucoma surgery. Risk factors for failure were identified using Cox proportional hazards ratio (HR). Results: The retention rate for five years follow-up was 66%. The cumulative probability of success at 1, 2, 3, 4 and 5 years was 82.6%, 76.7%, 73.9%, 72.3%, and 67.5%. Risk factors for failure were lower baseline IOP (HR=0.27, P=0.001), younger age (HR=0.25, P=0.02), and higher central corneal thickness (HR=0.18, P= 0.01). Pseudoexfoliation was associated with a higher success rate (HR= 0.39, P=0.02). IOP was decreased significantly from 20.0±5.6 mmHg at baseline to 15.6±4.6 mmHg at 5-year follow-up (P=0.001). The baseline number of glaucoma medications was 1.8±1.2, which decreased to 1.0±1.2 medications at 5 years. Conclusion: Trabectome surgery was associated with a good long-term efficacy and safety profile in this single-center case series with a high retention rate. A higher baseline IOP, older age, thinner cornea, and pseudoexfoliation glaucoma were associated with a higher success rate.
Improvement of the Torque-Speed Performance and Drive Efficiency in an SRM Using an Optimal Torque Sharing Function
Authors: Ye Wei , Ma Qishuang , Zhang Poming
Published: April 2018

In this paper, by evaluating extreme value of the qth-power current, a torque sharing function (TSF) family for reducing the torque ripples in the switched reluctance motor (SRM) is proposed. The optimization criteria of the TSF has two secondary objectives, including the maximization of the torque-speed range and the minimization of copper loss. The evaluation indices in terms of the peak phase current, the rms phase current, and the torque ripple factor are compared between the proposed TSF family and four conventional TSFs including linear, sinusoidal, exponential, and cubic TSFs. An optimization objective function that combines the maximum absolute value of the rate-of-change of the flux linkage (MAV-RCFL) and the qth-power of current is proposed and a weighting factor is used to balance the influence of the two optimization objectives. An optimal TSF can be easily obtained by solving the optimization problem from the TSF family. The proposed TSF is validated by using simulations and experiments with a three-phase 6/4 SRM with 7.5 kW, 3000 rpm, and 270 V DC-link voltage. The dynamic simulation model is implemented in Matlab/Simulink. The results demonstrate the validity and superiority of the proposed control method; the optimal TSF provides better torque-speed performance, and a better reduction in copper loss and torque ripples at high speed compared to the conventional TSFs obviously.
Peritoneal Carcinomatosis Targeting with Tumor Homing Peptides
Authors: Simón-Gracia Lorena , Hunt Hedi , Teesalu Tambet
Published: April 2018

During last decades multiple therapeutic approaches have been explored for improved management of peritoneally disseminated malignancies – a grim condition known as peritoneal carcinomatosis (PC). Intraperitoneal administration can be used to achieve elevated local concentration and extended half-life of the drugs in the peritoneal cavity to improve their anticancer efficacy. However, IP-administered chemotherapeutics have a short residence time in the IP space, and are not tumor selective. An increasing body of work suggests that functionalization of drugs and nanoparticles with targeting peptides increases their peritoneal retention and provides a robust and specific tumor binding and penetration that translates into improved therapeutic response. Here we review a progress in affinity targeting of intraperitoneal anticancer compounds, imaging agents and nanoparticles with tumor homing peptides. We review classes of tumor homing peptides relevant for PC targeting, payloads for peptide-guided precision delivery, applications for targeted compounds and the effects of nanoformulation of drugs and imaging agents on affinity-based tumor delivery.
Real-time Vehicle Roll Angle Estimation based on IoT low-cost devices and Neural Networks
Authors: Garcia-Guzman Javier , Prieto González Lisardo , Pajares Redondo Jonatan , Montalvo Martinez Mat Max , López Boada María Jesús
Published: April 2018

Given the high number of vehicle-crash victims, it has been established as a priority to reduce this figure in the transportation sector. For this reason, many of the recent researches are focused on including control systems in existing vehicles, to improve their stability, comfort and handling. These systems need to know in every moment the behavior of the vehicle (state variables), among others, when the different maneuvers are performed, to actuate by means of the systems in the vehicle (brakes, steering, suspension) and, in this way, to achieve a good behavior. The main problem arises from the lack of ability to directly capture several required dynamic vehicle variables, such as roll angle, from low-cost sensors. Previous studies demonstrate that low-cost sensors can provide data in real-time with the required precision and reliability. Even more, other research works indicate that neural networks are efficient mechanisms to estimate roll angle. Nevertheless, it is necessary to assess that the fusion of data coming from low-cost devices and estimations provided by neural networks can fulfill the reliability and appropriateness requirements for using these technologies to improve overall safety in production vehicles. Because of the increasing of computing power, the reduction of consumption and electric devices size, along with the high variety of communication technologies and networking protocols using Internet have yield to Internet of Things (IoT) development. In order to address this issue, this study has two main goals: 1) Determine the appropriateness and performance of neural networks embedded in low-cost sensors kits to estimate roll angle required to evaluate rollover risk situations. 2) Compare the low-cost control unit devices (Intel Edison and Raspberry Pi 3 Model B), to provide the roll angle estimation with this artificial neural network-based approach. To fulfil these objectives an experimental environment has been set up composed of a van with two set of low-cost kits, one including a Raspberry Pi 3 Model B, low cost Inertial Measurement Unit (BNO055 - 37€) and GPS (Mtk3339 - 53€) and the other having an Intel Edison System on Chip linked to a SparkFun 9 Degrees of Freedom module. This experimental environment will be tested in different maneuvers for comparison purposes. Neural networks embedded in low-cost sensor kits provide roll angle estimations very approximated to real values. Even more, Intel Edison and Raspberry Pi 3 Model B have enough computing capabilities to successfully run roll angle estimation based on neural networks to determine rollover risks situation fulfilling real-time operation restrictions stated for this problem.
Trace Gas Retrieval from AIUS：Algorithm Description and O3 Retrieval Assessment
Authors: Li Xiaoying , Cheng Tianhai , Xu Jian , Shi Hailiang , Zhang Xingying , Ge Shule , Zou Mingmin , Wang Hongmei , Wang Yapeng , Zhu Songyan , Miao Jing
Published: April 2018

AIUS (Atmospheric Infrared Ultraspectral Sounder) is an infrared occultation spectrometer onboard the Chinese GaoFen-5 satellite, which covers a spectral range of 2.4–13.3 μm (750–4100 cm−1) with a spectral resolution of about 0.02 cm−1. AIUS is designed to measure and study chemical processes of ozone (O3) and other trace gases in the upper troposphere and stratosphere around Antarctic. In this study, the corresponding retrieval methodology is described. The retrieval simulations based on the simulated spectra of AIUS have been carried out, with a focus on O3. The relative difference between the retrieved and the true O3 profiles is within 5% from the 15 km to 70 km and about 10% below 15 km. The corresponding averaging kernels illustrate that the overall retrieval information mainly come from the spectra, not the a priori. The retrieval experiments also demonstrate that the shape of the retrieved profiles resembles the shape of the true profile even if the shape of the a priori profile is different from that of the true profile. Further, we perform the O3 retrieval from the real ACE-FTS (Atmospheric Chemistry Experiment-Fourier Transform Spectrometer) measurements and compare the results with the official ACE-FTS Level-2 products. Overall, both profiles agree well in the stratosphere where the retrieval sensitivity is high. The relative difference between both profiles is about 15% below 70 km, which may due to the measurement errors and different forward model parameters.
A Multi-Resolution Approach for Audio Classification
Authors: Voronin Sergey , Grushin Alexander
Published: April 2018

We describe a multi-resolution approach for audio classification and illustrate its application to the open data set for environmental sound classification. The proposed approach utilizes a multi-resolution based ensemble consisting of targeted feature extraction of approximation (coarse scale) and detail (fine scale) portions of the signal under the action of multiple transforms. This is paired with an automatic machine learning engine for algorithm and parameter selection and the LSTM algorithm, capable of mapping several sequences of features to a predicted class membership probability distribution. A conditional probability approach is outlined for combining the predictions of different classifiers, trained over distinct scale feature sets. Initial results show an improvement in multi-class classification accuracy.
What Is the Heart? Anatomy, Form, Function, and Misconceptions
Authors: Buckberg Gerald D. , Nanda Navin C. , Nguyen Christopher , Kocica Mladen J.
Published: April 2018

Cardiac dynamics are traditionally linked to a left ventricle, right ventricle and septum morphology, a topography that differs from the heart’s 5-century-old anatomic description of containing a helix and circumferential wrap architectural configuration. Torrent Guasp’s helical ventricular myocardial band (HVMB) defines this anatomy and its structure, explains why the heart’s 6 dynamic actions of narrowing, shortening, lengthening, widening, twisting and uncoiling happen. This database raises questions about deductions behind “accepted cardiac mechanics”, and its functional aspects will challenge and overturn them. These suppositions include the LV, RV, and septum description, timing of mitral valve opening, isovolumic relaxation period, reasons for torsion/twisting, untwisting, reasons for longitudinal and circumferential strain, echocardiographic sub segmentation, resynchronization, RV function dynamics, and diastolic dysfunction’s cause and unrecognized septum impairment. Torrent Guasp’s revolutionary contributions may alter future understanding of the diagnosis and treatment of cardiac disease.
Diurnal and Seasonal Variations of Carbon Dioxide (CO2) Concentration in Urban, Suburban and Rural Areas around Tokyo-City
Authors: Imasu Ryoichi , Tanabe Yuka
Published: April 2018

Site environments and instrumental characteristics of carbon dioxide (CO2) measurements operated by local governments in the Kanto Plain, the center of which is Tokyo were summarized for this study. The observation sites were classified into environments of three types: urban, suburban, and woodland. Based on a few decades of accumulated hourly data, the diurnal and seasonal variations of CO2 concentrations were analyzed as a composite of anomalies from annual means recorded for each site. In urban areas, the highest concentrations appear before midnight in winter. The second peak corresponds to the morning rush hour and strengthening of the inversion layer. Suburban areas can be characterized as having the highest concentration before dawn and the lowest concentration during the daytime in summer in association with the activation of respiration and photosynthesis of vegetation. In these areas, concentration peaks also appear during the morning rush hour. Woodland areas show background features, with the highest concentration in early spring: higher than the global background by about 5 ppmv.
Starch-Jute fiber hybrid biocomposite modified with Epoxy resin layer: Fabrication and Experimental Characterization
Authors: Verma Akarsh , Joshi Kamal , Gaur Amit , Singh V. K.
Published: April 2018

In this article, bio-composites derived from starch-glycerol biodegradable matrix reinforced with jute fibers have been fabricated using the wet hand lay-up and compression moulding techniques. Samples having different weight percentages of jute fiber in the starch matrix have been analysed. The fibers surface was chemically treated by alkaline sodium hydroxide for improving the interphase bonding between fiber and matrix. Tensile test for the composites were done and the sample with highest tensile strength was selected for further tests that included water absorption, scanning electron microscopy and thermal analysis. It has been concluded that the ultimate tensile strength was found to be maximum for the composition of 15% fiber by weight composite as 7.547 MPa without epoxy coating and 10.43 MPa with epoxy coating. The major disadvantage of bio-composite is its high water absorption property, which in this study has been inhibited by the epoxy resin layer. Herein, the results of various tests done disclose a noteworthy improvement in the overall properties of bio-composite, in comparison to the neat biodegradable starch matrix.
Cardiovascular Health of Construction Workers in Hong Kong: A Cross-Sectional Study
Authors: Chung Joanne Wai-Yee , Wong Bonny Yee-Man , Yan Vincent Chun-Man , Chung Louisa Ming-Yan , So Henry Chi-Fuk , Chan Albert
Published: April 2018

Objectives: 1) To describe the cardiovascular health of the construction workers in Hong Kong, 2) to examine the demographic differences in cardiovascular health, and 3) to examine the association between modifiable lifestyle behaviors and cardiovascular conditions. Methods: 626 registered construction workers were included in the analysis. Blood chemistry, blood pressure, weight and height were measured. Face-to-face questionnaire interview was conducted. T-tests and One-way ANOVAs were used to compare the cardiovascular health score, cardiovascular outcomes, and lifestyle behaviors by demographic characteristics. Logistic regressions were performed to assess the cardiovascular outcomes by lifestyle behaviors. Results: Two-thirds of the construction workers failed to achieve three out of the seven “ideal” cardiovascular health indicators. The younger, more educated, and female subjects had better cardiovascular health scores than their counterparts. The ideal fish and seafood consumption was associated with 1) ideal weight status and 2) ideal cholesterol level, whereas less soft drink consumption was associated with ideal cholesterol level. Conclusions: The findings highlighted the importance of promoting cardiovascular health in the construction industry. This study provided insights for future interventions, which should include increasing fish and seafood intake, decreasing soft drink consumption, and enhancing the health literacy amongst older, less educated, and male construction workers.
Applying STEEPLE to course and curriculum design
Authors: Kelly Peter Colin
Published: April 2018

When it comes to course design in Higher Education, everything from learning theory and learning design theory to needs analysis and potential markets should shape our thinking. A group based course design task on the Post Graduate Certificate in Higher Education (PGCert. HE) at the University of Greenwich (UoG) provided the context within which my colleagues and I were able to bring a key aspect of our professional experience and expertise to course development. Ourbusiness background and an interest in strategic modelling in business led us to adopt the ‘STEEPLE’ model, which is an extension of the ‘PEST’ and ‘PESTLE’ models that preceded it and which is used in strategic decision making in business worldwide.
Flipped classroom: a student experience
Authors: Li Fon Yan , Boden Gemma
Published: April 2018

This is an opinion piece from a paramedic student who was introducted to the concept of flipped classroom.  Hacing previously studied at higher education, this was a new way of learning and required an element of pre-learning and enhanced engagement.  This is written from the student's view-point, touching on the positives and negatives of her experience, as well as introducing the model of flipped learning.