bluuebunny/crossref_metadata_2025 huggingface dataset:
Model-based motion compensation for corneal topography by optical coherence tomography
Authors: Wagner Joerg , Robledo Lucio , Pezold Simon , Eggenschwiler Laura , Hasler Pascal , Goldblum David , Cattin Philippe C.
Published: June 2020

Corneal topography is an essential tool in ophthalmology, in particular for surgical planning and diagnostics. Optical coherence tomography (OCT) enables cross-sectional or volumetric imaging with high resolution. It is, however, not widely used for corneal topography. A major reason for this is that conventional beam-scanning OCT is susceptible to eye motion compared to established modalities, which measure corneal shape in a single shot. To overcome this limitation, we propose a novel pipeline for motion-compensated OCT-based corneal topography. The pipeline includes three main features: (1) continuous, two-dimensional scanning; (2) the three-dimensional continuous motion compensation in postprocessing; and (3) regularised Zernike reconstruction. First, we evaluated our method on an eye phantom that is moved to mimic typical eye motion. The proposed motion compensation was able to determine and correct the movements of the phantom. Second, we performed an in vivo study on 48 eyes, measuring each eye twice with our OCT-based topography, Placido disc topography (Atlas 9000, Carl Zeiss Meditec), and Scheimpflug (Pentacam, Oculus) topography. We then compared the performance of the OCT-based topography to the reference topographies in terms of repeatability and equivalence. The results confirm the necessity and efficiency of the presented motion compensation and validate the proposed methods for scanning and reconstruction.
Fragmentos de Aristófanes
Authors: Sacconi Karen Amaral
Published: June 2020

Este trabalho tem por objetivo iluminar o corpus de fragmentos da comédia antiga, em geral ofuscado pelas 11 comédias preservadas de Aristófanes. Apresenta-se aqui a primeira tradução anotada, para o português, dos fragmentos do poeta cômico e de suas fontes. O volume contém ainda uma introdução dedicada às fontes desses excertos, do contexto em que surgiram e como se deu sua transmissão. Ele reúne e organiza informações úteis aos estudos sobre lexicografia e trata também da recepção de Aristófanes na própria antiguidade.
Genotyping of rabbit hemorrhagic disease virus detected in diseased rabbits in Egyptian Provinces by VP60 sequencing
Authors: Erfan Ahmed M. , Shalaby Azhar G.
Published: June 2020

Background and Aim: Rabbit hemorrhagic disease (RHD) is an economically important disorder of rabbits, where infection results in severe losses to the meat and fur industries. Our goal was to characterize the RHD virus (RHDV) strains currently circulating in different regions of Egypt.

Materials and Methods: Fifty rabbits suspected of harboring RHDV from 15 Egyptian governorates were evaluated. Diseased rabbits were identified by clinical signs and postmortem lesions. RHDV was confirmed through hemagglutination assay (HA) and polymerase chain reaction (PCR). Partial sequencing of the VP60 gene was performed for genotyping.

Results: From 50 rabbits, we identified 16 cases of RHDV (32%) by HA and PCR, including seven males and nine females. We identified two distinct genotypes through sequencing of an amplified fragment of the virus VP 60 gene. One group is composed of those circulating primarily in upper Egypt, which is closely related to the classical G3-G5 virus strains, and the second group, circulating predominantly in lower Egypt, was more closely related to the RHDV2 variant. The overall nucleotide sequence identity ranged from 78.4% to 100%, and identity with the vaccine strains ranged from 78.8% to 91.1%.

Conclusion: Our results constitute important documentation of RHDV strains currently circulating in Egypt. The findings suggest that there may be a limit to the effectiveness of currently applied vaccine strains as this formulation may not cover all circulating strains. A wider investigation that includes both domestic and wild rabbits will be needed to identify appropriate control measures for this disease.
Apoio psicossocial em tempos de COVID-19: experiências de novas estratégias de gestão e ajuda mútua no sul da Bahia, Brasil
Authors: Cruz Náira Menezes Luz Vasconcelos , Souza Edilza Bastos de , Sampaio Catilene Souza Florencio , Santos Adriana Jesus Matias dos , Chaves Sarita Virolli , Hora Ronoel Nunes da , Souza Rozemere Cardoso de , Santos Josenaide Engracia dos
Published: June 2020

Este artigo relata experiências de profissionais e usuários de serviços da Rede de Atenção Psicossocial (RAPS), nos municípios de Ilhéus e Itabuna, os quais estão entre os que lideram as estatísticas em número de casos da COVID-19 no estado da Bahia, Brasil. Descreve-se a criação de um grupo de WhatsApp para usuários de um Centro de Atenção Psicossocial (CAPS), com impactos na proximidade das interações entre eles, e entre eles e a equipe e a comunidade. A experiência é encorajadora, na medida em que a mútua ajuda nasce e produz autonomia e protagonismo. A outra experiência baseia-se em movimentos de uma gestora da RAPS, para articular usuários do CAPS e Atenção Primária à Saúde, para apoio emocional e respostas às demandas em momentos de pandemia e isolamento social. Nesses cenários, as experiências têm criado e fortalecido novas estratégias de saúde mental, ampliando atores sociais, ferramentas e setores, na produção do cuidado na comunidade.
A prática do núcleo de apoio à saúde da família do Recife no enfrentamento à pandemia COVID-19
Authors: Oliveira Maria Angélica Bezerra de , Monteiro Laís De Souza , Oliveira Rebeca De Castro , Moreira Tarcilla Sousa , Marques Ana Carolina Fonseca , Silva Ursula Maria de Araújo , Oliveira Nadvânia Albuquerque , Pereira Gladys Fernanda Coelho , Silva Ana Cláudia Serra , Santana Renata Morais
Published: June 2020

Este artigo tem por objetivo relatar a experiência de reorganização do processo de trabalho do Núcleo de Apoio a Saúde da Família (Nasf) na Atenção Primária a Saúde (APS) visando a pandemia do COVID-19 no município do Recife, Pernambuco. Adequando-se ao contexto de cada território e demandas específicas das equipes de Saúde da Família (eSF), as atividades e ações do Nasf foram gradativamente reformuladas para manter a continuidade do cuidado no território frente a pandemia do COVID-19. As atividades realizadas são apresentadas no presente artigo em três eixos: atividades ligadas diretamente aos usuários, suporte as eSF e seus profissionais e as ações nos territórios. Consideramos que as possibilidades de atuação do Nasf ampliaram a capacidade de visão da comunidade e o desenvolvimento de habilidades para o enfrentamento deste desafio e outros tantos que virão no âmbito da APS.
Saúde do trabalhador em tempos de COVID-19: a experiência do município de Londrina
Authors: Fillis Michelle Moreira Abujamra , Dellaroza Mara Solange Gomes , Machado Rosilene Aparecida , Pelaquim Tatiane Aparecida Alves , Coelho Valdelice Vaz , Barbosa Valéria Cristina Almeida de Azevedo , Alcântara Vânia Cristina da Silva , Trelha Celita Salmaso
Published: June 2020

A pandemia da COVID-19 está sendo um grande desafio para a saúde e o processo de trabalho como um todo deve ser considerado na elaboração e implantação de estratégias para seu enfrentamento. A necessidade de distanciamento social para evitar a proliferação rápida do vírus, de acordo com as orientações da Organização Mundial de Saúde, levou milhares de pessoas ao trabalho remoto, fechamento de indústrias, serviços e escolas em todos os níveis de ensino. Diante do exposto, o objetivo do presente estudo é relatar a experiência de um programa de prevenção à saúde do trabalhador no enfrentamento da pandemia do COVID-19 no município de Londrina e região.
COVID-19 & informal settlements: is Stay Home safe?
Authors: Nix Emily , Paulose Jacob , Lakhanpaul Monica , Factor-Litvak Pam , Parikh Priti , Altamirano-Medina Hector , Bou Karim Yasmin , Manikam Logan
Published: June 2020

Disproportional burden of COVID-19 and vulnerability to containment measures in informal settlements have been recognised, however, the role of poor housing conditions in propagating these remains neglected. Poor housing conditions will make it difficult to effectively implement social distancing measures. With increased time spent in cramped, dark and uncomfortable indoor environments, water and sanitation outside the home, and no outdoor space, higher exposure to existing health hazards and high levels of stress, with women and children most vulnerable, are anticipated. We reflect on these interconnections and recommend immediate measures and the long-term need for adequate housing for health and well-being.
Can we count on each other? An inquiry about Portuguese citizens’ individual and relational dispositions
Authors: Minas Maria
Published: June 2020

Todos os seres humanos têm a capacidade de contribuir para o bem-estar coletivo. Este artigo apresenta um estudo quantitativo que envolveu a análise das respostas de 1187 cidadãos portugueses a um questionário online, com o objetivo de analisar a sua satisfação com a vida (SLS), sentido de comunidade (BSCS), apoio social percebido (SPS), comparação social (SCS), competição (SAIS), vergonha externa (OASS) e desejo de contribuir (WCS), tendo em conta a influência de fatores sociodemográficos como o sexo e a situação económica. Através da criação de grupos, cruzando os valores respeitantes à Competição e aos Recursos, os valores mais altos nas variáveis globais de SLP, SPS, BSCS e os valores mais baixos nas variáveis globais de OASS concentraram-se predominantemente no grupo alta competição, baixos recursos. Relativamente à escala WCS, os valores mais baixos concentraram-se nos grupos de alta competição e os valores mais altos nos grupos de baixa competição. Não foram encontradas diferenças significativas entre os grupos na variável global SCS. Estes resultados sugerem que o foco em valores coletivos de confiança mútua estão associados a uma maior satisfação, apoio social e desejo de contribuir, envolvendo uma menor necessidade para competir e assumir posturas de defensividade.
The expression of lncRNA-MALAT1 in breast cancer patients and its influences on prognosis
Authors: Sun Zhenxuan , Liu Jinquan , Liu Jintao
Published: June 2020

This study aimed to explore the expression of lncRNA-metastasis associated lung adenocarcinoma transcript 1 (lncRNA-MALAT1) in breast cancer (BC) patients and its influences on the prognosis of the patients. A total of 120 BC patients admitted to our hospital were enrolled as a BC group, of which 58 patients at I/II stage were treated with breast-conserving surgery as an operation group, and the other 62 patients at III/IV stage were treated with neoadjuvant chemotherapy combined with breast-conserving surgery as a combination group. Meantime, 100 healthy people in physical examination during the same period were enrolled as a normal group. The expression of serum lncRNA-MALAT1 in the subjects was determined, and the expression in BC patients and its influences on the patients were analyzed. LncRNA-MALAT1 was over-expressed in patients from the BC group, and the area-under-the-curve (AUC) of it for diagnosing BC was 0.911. After treatment, the expression of lncRNA-MALAT1 in the operation group and the combination group significantly decreased, and the expression of it in patients with good prognosis was greatly lower than that in patients with poor prognosis. The AUC of lncRNA-MALAT1 for predicting poor prognosis was 0.838, and TNM staging, pathological differentiation, tumor diameter, and lncRNA-MALAT1 were independent prognostic factors for poor prognosis of the patients. Furthermore, low expression of lncRNA-MALAT1 was associated with a relatively high 5-year overall survival (OS) of BC patients. The expression of lncRNA-MALAT1 was up-regulated in BC patients, while it was down-regulated in BC patients treated with breast-conserving surgery combined with neo-adjuvant chemotherapy, so lncRNA-MALAT1 can be used as a potential indicator for early diagnosis and prognosis prediction of BC patients.
Bazedoxifene effects on osteoprotegerin, insulin-like growth factor, tumor necrosis factor and bone mineral density
Authors: Ma Yonggang , Chai Zhen , Ren Longlong , Hu Qiaolong
Published: June 2020

To observe the clinical effect of estrogenic drugs (Bazedoxifene) on bone targeting in the treatment of osteoporosis and explore its mechanism. Methods:112 patients with postmenopausal osteoporosis who received Bazedoxifene drugs in our hospital from January to December 2018 were collected as a study group, and 56 patients treated with calcium alone were collected as a control group. the risk of adverse events such as bone mineral density, osteoprotegerin (OPG), insulin-like growth factor (IGF), tumor necrosis factor (TNF-Î±), and fracture after treatment were analyzed before and after treatment. Results: There was no significant difference in the mean lumbar positive position (L2-4) and right femoral neck bone density and OPG, IGF, TNF-Î± level between the two groups before treatment (P>0.05). The total effective rate of clinical treatment in the study group was 88.39%, the control group was 23.21%, the difference between the two groups was statistically significant (PË‚0.05). After treatment, the mean lumbar positive position (L2-4) and the right femoral neck bone density and OPG, IGF in the study group were higher than those in the control group, lower than those in the control group (P<0.05). the occurrence of adverse events such as fracture, spinal deformation and fatigue in the study group after 12 months of treatment was significantly lower than that in the control group (P<0.05), but there was no significant difference in the occurrence of hot flashes and venous thromboembolism between the two groups (P>0.05). Conclusion: Bazedoxifene is an effective drug for the treatment of postmenopausal osteoporosis. It can not only prevent the rapid loss of bone mass, effectively relieve the symptoms of menopause, but also improve bone density and reduce the risk of fracture.
Patrinia herba aqueous extract on the proliferation, apoptosis, invasion and migration of hepatocellular carcinoma cells
Authors: Guan Zhenhua , Chen Jing , Li Xueliang
Published: June 2020

This study aims to study the effect and mechanism of Patrinia herba aqueous extract on proliferation, apoptosis, invasion and migration of hepatocellular carcinoma cells. Hepatocellular carcinoma cells MHCC97-H were treated with 2.5, 5, 10 mg/mL P. herba aqueous extract, cell counting kit 8 (CCK-8), flow cytometry, plate cloning experiments, and Transwell measured cell survival, apoptosis, colony formation, invasion, and migration, respectively. Real-time quantitative PCR (qPCR) and western blot were used to detect long non-coding RNA (lncRNA) HTR2A-AS1 and expression of proteins P21, Caspase-3, E-cadherin and matrix metalloproteinase-2 (MMP-2), respectively. Transfected pcDNA3.1-HTR2A-AS1 in MHCC97-H cells, or transfected si-HTR2A-AS1 and treat with 10 mg/mL P. herba aqueous extract to evaluate their roles in cell proliferation, apoptosis, invasion, and migration. Different concentrations of P. herba aqueous extract significantly reduced the survival rate, colony formation, number of migrating cells, number of invading cells, and MMP-2 protein expression of MHCC97-H cells, and obviously increased the cell apoptosis rate, the expression levels of Caspase-3, E-cadherin protein and HTR2A-AS1 (P<0.05), which were all concentration-dependent. Overexpression of HTR2A-AS1 evidently decreased the survival rate, colony formation, number of migrating cells, number of invading cells, and MMP-2 protein levels in MHCC97-H cells, while remarkably enhanced the apoptosis rate of cells, P21, Caspase-3, and E-cadherin protein levels and HTR2A-AS1 expression level (P<0.05). Inhibition of HTR2A-AS1 greatly improved the survival rate, the number of clone formation, the number of migrating cells, the number of invading cells and the expression of MMP-2 protein of MHCC97-H cells treated with P. herba aqueous extract, dramatically reducing the cell apoptosis rate, P21, Caspase-3, E-cadherin protein levels and HTR2A-AS1 expression levels (P<0.05). P. herba aqueous extract may inhibit the proliferation, invasion and migration of hepatocellular carcinoma cells by up-regulating the expression of HTR2A-AS1 in hepatocellular carcinoma cells and induce apoptosis.
Down-regulation of miRNA-196b expression inhibits the proliferation, migration and invasiveness of HepG2 cells while promoting their apoptosis via the PI3K/Akt signaling pathway
Authors: Xu Fanggui , Zhu Feng , Wang Wulin , Gao Wenjie , Chen Xin , Yu Chunzhao
Published: June 2020

The purpose of this study was to investigate the effects of microRNA-196b (miRNA-196b) on proliferation, migration, invasiveness and apoptosis of hepatocellular carcinoma cell line (HepG2), and the mechanism involved.   MiRNA-196b inhibitor or negative control were transfected into HepG2 cells, while empty liposome vector was used as normal control. The results of transfection were assessed using real-time quantitative polymerase chain reaction (qRT-PCR). Cell proliferation, migration, invasiveness and apoptosis were determined using cell counting kit 8 (CCK-8), scratch test, Transwell invasion assay, and flow cytometric analysis, respectively. The expressions of PIK3, Akt and p-Akt proteins were determined using Western blotting. The HepG2 cells were also treated with PI3K/Akt signaling pathway inhibitor LY294002, and its effect on cell proliferation, migration, invasion, and apoptosis, and expressions of PIK3, Akt, and p-Akt proteins were determined. The results of RT-PCR showed that the relative expression of miRNA-196b in the inhibitor group (0.42 ± 0.13) was significantly lower than that in the blank control group (0.96 ± 0.10) and the negative control group (1.01 ± 0.32) (p < 0.05). The miRNA-196b inhibitor significantly and time-dependently reduced the invasiveness, proliferation migration abilities of HepG2 cells, while promoting their apoptosis (p < 0.05). The expressions of PIK3 and p-Akt proteins were significantly down-regulated in the inhibitor group, when compared with normal and negative control groups (p < 0.05). However, there were no significant differences in the expression of Akt protein among the groups (p > 0.05). After treatment of HepG2 cells with PI3K/Akt signaling pathway inhibitor LY294002, the proliferative, migratory and invasive abilities of cells in the treatment group were significantly enhanced, while cell apoptosis was significantly reduced (p < 0.05). Similarly, the protein expressions of PIK3 and p-Akt in the non-treatment group was significantly upregulated, relative to the treatment group (p < 0.05), but there was no significant difference in the expression of Akt protein between the two groups (p > 0.05). Downregulation of miRNA-196b expression inhibits the proliferation, migration and invasiveness of HepG2 cells, while promoting their apoptosis via a mechanism involving the PI3K/Akt signaling pathway.
Nitric oxide donor andrographolide enhances humoral and cell-mediated immune responses
Authors: Zhang Bing , Yang Bo , Du Lijun , Guo Yunfen
Published: June 2020

The present study was aimed to investigate the regulatory effect of Nitric oxide  donor andrographolide (Q-1) on cellular immunity in patients with chronic hepatitis B. Peripheral blood mononuclear cells (PBMCs) were isolated from patients with chronic hepatitis B. Cell viability was assessed using 3"‘(4,5"‘dimethyl"‘thiazol"‘2"‘yl)"‘2,5"‘diphenyl"‘2H"‘tetrazolium bromide (MTT) assay. The levels of expression of interferon gamma (IFN-Î³), interleukin 4 (IL-4), interleukin 10 (IL-10) and tumor necrosis factor Î± (TFN-Î±) in PBMCs of patients with chronic hepatitis B were determined using real-time quantitative polymerase chain reaction (qRT-PCR). Anti-HBV effect of isolated HBV DNA was also assessed in vitro. Q-1 had no significant effect on the viability of Vero and isolated PBMCs (p > 0.05). The expression of IFN-Î³ in PBMCs of control patients significantly and time-dependently increased after treatment with Q-1, but the expressions of IL-4 and IL-10 in PBMCs of patients with chronic hepatitis B were decreased significantly and time-dependently (p < 0.05). The function of Th1 cells was significantly enhanced by Q-1 treatment (p < 0.05). The mean replication of HBV DNA in HepG2cells at the three concentrations of Q-1 and adefovir were 3.96 í— 106, 4.13 í— 106 and 4.53 í— 106 copies/mL, respectively. There was no significant difference in the expression of HBV DNA among the concentration levels. These results indicate that andrographolide enhances the function of HBV-specific T cells in patients with chronic hepatitis B.
Equality and Merit. Through Experiments to Normative Justice
Authors: Leist Anton
Published: June 2020

When we want to justify claims against one another, we discover that conceptual thought alone is not sufficient to legitimize property and income in the relative and proper proportions among members of a productive group. Instead, the basis for justification should also be seen in motivational states, validated less by rational thought than by an effective behaviour. To circumnavigate otherwise dangerously utopian claims to justice, the social sciences, and especially behavioural economics, are the most reliable basis for normative distributive justice. This article builds on recent findings of experiments, first of all in order to give proof of the extent to which a general behavioural tendency towards equality is widespread among people, and second of all in order to highlight ‘desert’ and ‘need’ as the crucial criteria of just distribution, which will then sum up to justified inequality in the economic sphere.
Habermas’s Politics of Rational Freedom: Navigating the History of Philosophy between Faith and Knowledge
Authors: Verovšek Peter J.
Published: June 2020

Despite his hostility to religion in his early career, since the turn of the century Habermas has devoted his research to the relationship between faith and knowledge. His two-volume Auch eine Geschichte der Philosophie is the culmination of this project. Spurred by the attacks of 9/11 and the growing conflict between religion and the forces of secularization, I argue that this philosophy of history is the centerpiece of an important turning point in Habermas’s intellectual development. Instead of interpreting religion merely as part of the history of postmetaphysical thinking, Habermas now sees it as a crucial normative resource for both philosophy and social cohesion in the future aswell. Despite its backward-looking approach,my basic thesis is that this book is best understood as a forward-looking appeal for a tolerant, self-reflective democratic politics that brings religious and secular citizens together dialogically through the cooperative use of their rational freedom.
Luck Egalitarianism and Relational Egalitarianism: An Internal Tension in Cohen’s Theory of Justice
Authors: Chen Jiangjin
Published: June 2020

Relational Egalitarianism focuses on the construction of equal social relationships between persons. It strongly opposes luck egalitarianism, which understands equality as a distributive ideal. In Cohen’s theory of justice, luck egalitarianism and relational egalitarianism simultaneously exist, and Cohen provides arguments corresponding to each. In this paper, we explore the manifestation of tension between these two forms of egalitarianism in his theory. In addition, we also reconstruct some possible solutions provided by Cohen to soften this tension, including the three approaches of market mechanism, egalitarian ethos and value pluralism, and find them to be unsuccessful. This tension is a serious challenge that needs to be addressed in Cohen’s theory of justice.
Technological and antioxidant properties of proteins obtained from waste potato juice
Authors: Jeżowski Paweł , Polcyn Karolina , Tomkowiak Agnieszka , Rybicka Iga , Radzikowska Dominika
Published: June 2020

The article presents the technological and antioxidant properties of potato juice (PJ) protein concentrate obtained by the novel ultrafiltration method. Commercial products, obtained from waste PJ by the traditional method of acid coagulation of proteins, were studied for comparison. Functional properties such as water or oil absorption, foaming capacity, and foam stability (FS) as well as solubility at various pH were assessed. Moreover, the total phenolic compound content, antioxidant activity, and mineral composition were determined. The results showed that PJ protein concentrate obtained by ultrafiltration has good oil absorption properties (6.30 mL/g), which is more than two times higher than the commercial proteins used in the comparison (P2 = 2.33 mL/g and P3 = 2.67 mL/g). Moreover, the ability to create and stabilize foam was also higher (FS ranging from 20.0% at pH = 10 to 11.3% at pH = 2 after 60 min of testing). It had higher content of macro- and microelements and antioxidant activity compared to other samples. Therefore, it is possible to obtain interesting potato protein concentrate from the waste product of the starch production process, which may be an interesting raw material for enriching food.
Photopoetics: Sisyphus Outdone, the Apostrophal Subject and the Elusive Image
Authors: Sánchez-Pardo Esther
Published: June 2020

In Sisyphus Outdone (2012), Nathanaël’s particular tribute to Albert Camus’ The Myth of Sisyphus (1942), the reader faces a challenging hybrid text in which the verbal and visual dimensions intermingle to produce an idiosyncratic type of narrative. Fragmentary, elliptical, a web of quotations, dictums, and meditations on the difficult condition of the individual in the current image-saturated scenario of the first decades of the 21st century, the text manages to propose a rigorous reflection upon crucial aspects of representation from History and temporality, to the Subject now, photography, catastrophe theory, architecture, failure and translation, among the most salient. Sisyphus, I suggest, exhibits a strategic photopoetics which operates as a self-reflective mechanism contributing to the persistence of an impermanent liminal subject and to the (re)production of textuality and the proliferation of voices against silence.
Pilot-scale production of polylactic acid nanofibers by melt electrospinning
Authors: Koenig Kylie , Langensiepen Fabian , Seide Gunnar
Published: June 2020

Melt electrospinning has been used to manufacture fibers with diameters in the low micrometer range, but the production of submicrometer fibers has proven more challenging. In this study, we investigated the feasibility of fabricating polylactic acid nanofibers using polymer grades with the increasing melt flow rates (15–85 g/10 min at 210°C) by melt electrospinning with a 600-nozzle pilot-scale device featuring an integrated climate control system realized as a glass chamber around the spinneret. Previous experiments using this device without appropriate climate control produced fibers exceeding 1 µm in diameter because the drawing of fibers was inhibited by the rapid cooling of the polymer melt. The integrated glass chamber created a temperature gradient exceeding the glass transition temperature of the polymer, which enhanced the drawing of fibers below the spinneret. An average fiber diameter of 810 nm was achieved using Ingeo Biopolymer 6252, and the finest individual fiber (420 nm in diameter) was produced at a spin pump speed of 5 rpm and a spinneret set temperature of 230°C. We have therefore demonstrated the innovative performance of our pilot-scale melt-electrospinning device, which bridges the gap between laboratory-scale and pilot-scale manufacturing and achieves fiber diameters comparable to those produced by conventional solution electrospinning.
„Commercium nach dem Sinn Jesu“
Authors: Dorfner Thomas
Published: June 2020

This paper analyses the market behaviour of the Moravian Church around 1800 as illustrated by the transatlantic trade with Labrador. The pietistic religious community, which originated in Herrnhut/Saxony, founded numerous missionary stations and settlements in the Atlantic world after 1732. In the course of this expansion, a broad range of trade opportunities opened up to the Moravians, which they utilised to finance their exceedingly expensive missionary activities. As this paper sets out, they founded their own Ship’s Company in London in 1770, which imported sought-after raw materials to Great Britain, such as whalebone or fur from Labrador. However, the leadership committee, known as the Unity Elders Conference, imposed strict regulations on the market activities of all Moravians. All trade activities had tobe consistent with biblical standards. This was intended to ensure that the individual merchant or missionary remained free of sin. The Unity Elders considered fair prices tobe of particular importance. This belief also served to distinguish the community from the large number of non-pietistic merchants and their trading practices.
„Große Unternehmungen sind dringend zu widerraten“ – Die Wirtschaft der Deutschen Brüderunität zwischen Ideal und Reform
Authors: Kokel Susanne
Published: June 2020

This essay examines the process of the fundamental reform undertaken by the Moravian Brethren in Germany at the end of the 19th century, building a separate and professionally managed business area within the church. An analysis of institutions, practices and semantics helps to explain this institutional change of a religious entrepreneur. Finally, the case of Sunday work in the church-owned companies illustrates the conditions set for corporate practices by the new institutional structure.
Wettbewerb als „Glaubensbekenntnis“? „Religiöse“ Semantiken im Deutschen Handelstag (1861–1914)
Authors: Gehlen Boris
Published: June 2020

On the basis of general discussions, the paper examines the “religious” functions of competition within the Deutsche Handelstag: firstly, the sensegiving function of “competition”, secondly, its relevance in questions of interest policy and thirdly, semantic change and ritualised communication. By referring to cultural studies approaches, the paper shows that institutions and market practices were discursively (or “religiously”) rationalised and legitimised even if they had nothing in common with competition anymore.

The concept of competition remained undefined in content, was sometimes only ritualised rhetoric and changed semantically as was opportune. Nevertheless, given that interest politics are specific to space and time, an analysis cannot solely rely on abstract cultural studies approaches: The DHT's policy positions cannot be explained by “religious” belief in competition alone as pragmatism was strong. At the same time, a cultural studies perspective contributes to a better understanding of the logic of organisation because it focuses on the changes in semantics and (ritualised) acts of self-assurance.
Geldtheorie und -politik in Preußen Mitte des 18. Jahrhunderts
Authors: Greitens Jan
Published: June 2020

In the history of economic thought, monetary theories in the Germanspeaking world of the early modern era are considered backward compared to the approaches in other European countries. This backwardness can be illustrated by two authors from the mid-18th century who were not only contemporaries but also successively in the service of Frederick II (“the Great”) of Prussia. The first is Johann Philipp Graumann, one of the 'projectors' of the 18th century. As master of the mints in Prussia, he developed a coin project, where he tried to implement a new monetary standard to promote trade, generate seigniorage income and implement the Prussian coins as a kind of a reserve currency. In his writings, he developed a typical mercantilistic monetary theory with a clear understanding of the mechanism in the balance of payments. But even when he tried to include credit instruments, he did not take banks or broader financial markets into account. The second thinker is Johann Heinrich Gottlob Justi, who took the opposite position concerning the coin project as well as in his theory. He defended a strictly metalistic monetary approach where the value of money is only based on the metal's value. While Graumann rejected the English coin system, Justi recommended its laws for countries without their own mines, because the sovereign should not misuse his right of coinage. For him, the monetary system had tobe reliable and stable to serve trade and economic development.
Multiparty Non-Interactive Key Exchange and More From Isogenies on Elliptic Curves
Authors: Boneh Dan , Glass Darren , Krashen Daniel , Lauter Kristin , Sharif Shahed , Silverberg Alice , Tibouchi Mehdi , Zhandry Mark
Published: June 2020

We describe a framework for constructing an efficient non-interactive key exchange (NIKE) protocol fornparties for anyn≥ 2. Our approach is based on the problem of computing isogenies between isogenous elliptic curves, which is believed to be difficult. We do not obtain a working protocol because of a missing step that is currently an open mathematical problem. What we need to complete our protocol is an efficient algorithm that takes as input an abelian variety presented as a product of isogenous elliptic curves, and outputs an isomorphism invariant of the abelian variety.

Our framework builds acryptographic invariant map, which is a new primitive closely related to a cryptographic multilinear map, but whose range does not necessarily have a group structure. Nevertheless, we show that a cryptographic invariant map can be used to build several cryptographic primitives, including NIKE, that were previously constructed from multilinear maps and indistinguishability obfuscation.
Recovering Secrets From Prefix-Dependent Leakage
Authors: Ferradi Houda , Géraud Rémi , Guilley Sylvain , Naccache David , Tibouchi Mehdi
Published: June 2020

We discuss how to recover a secret bitstring given partial information obtained during a computation over that string, assuming the computation is a deterministic algorithm processing the secret bits sequentially. That abstract situation models certain types of side-channel attacks against discrete logarithm and RSA-based cryptosystems, where the adversary obtains information not on the secret exponent directly, but instead on the group or ring element that varies at each step of the exponentiation algorithm.

Our main result shows that for a leakage of a single bit per iteration, under suitable statistical independence assumptions, one can recover the whole secret bitstring in polynomial time. We also discuss how to cope with imperfect leakage, extend the model to k-bit leaks, and show how our algorithm yields attacks on popular cryptosystems such as (EC)DSA.
Self-dual DeepBKZ for finding short lattice vectors
Authors: Yasuda Masaya
Published: June 2020

In recent years, the block Korkine-Zolotarev (BKZ) and its variants such as BKZ 2.0 have been used as de facto algorithms to estimate the security of a lattice-based cryptosystem. In 2017, DeepBKZ was proposed as a mathematical improvement of BKZ, which calls LLL with deep insertions (DeepLLL) as a subroutine alternative to LLL. DeepBKZ can find a short lattice vector by smaller blocksizes than BKZ. In this paper, we develop a self-dual variant of DeepBKZ, as in the work of Micciancio and Walter for self-dual BKZ. Like DeepBKZ, our self-dual DeepBKZ calls both DeepLLL and its dual variant as main subroutines in order to accelerate to find a very short lattice vector. We also report experimental results of DeepBKZ and our self-dual DeepBKZ for random bases on the Darmstadt SVP challenge.
Thalidomide-induced serious RR interval prolongation (longest interval >5.0 s) in multiple myeloma patient with rectal cancer: A case report
Authors: Huang Li , Kuang Yuemin , Jiang Zhiyong , Zhu Yan , Luo Xinguo , Shi Fangjing , Hu Shanshan , Gao Xinfang
Published: June 2020

Primary secondary tumor increased recently with the use of immunomodulatory drugs in patients with multiple myeloma (MM). However, MM with prior diagnosis of primary secondary tumor is relatively rare. In this study, we reported an MM patient with prior diagnosis of rectal cancer. In brief, an 85-year-old man was first diagnosed with rectal cancer. Given the age, heart failure and small-cell hypochromic anemia (hemoglobin level: 54 g/L), rectal cancer resection was not advised and symptomatic treatments were performed (including sufficient iron supplementation). Eight months later, the patient was diagnosed with MM due to worsening anemia. Anemia and heart failure were corrected after three cycles of treatment with thalidomide, dexamethasone and capecitabine. Radical resection of rectal carcinoma (Hartmann) was finally performed due to acute abdominal distension. Meanwhile, RR interval prolongation (longest interval >5.0 s) and atrial fibrillation occurred in the fifth cycle treatment. One month after discontinuation of thalidomide, RR interval returned to normal range, while atrial fibrillation developed into persistent atrial fibrillation.
Crystal structure of catena-poly[chlorido-(μ2-formato-κ2
O:O′)-(1,10-phenathroline-κ2
N,N′)copper(II)], C26H18Cl2Cu2N4O4
Authors: Li Xia , Liu Shangjun , Shen Mingle , Yan Weihong
Published: June 2020

C26H18Cl2Cu2N4O4, monoclinic, P21/c (no. 14), a = 9.5129(9) Å, b = 17.8130(17) Å, c = 15.2973(12) Å, β = 110.975(5)°, V = 2420.4(4) Å3, Z = 4, R
gt(F) = 0.0269, wR
ref(F
2) = 0.0929, T = 293(2) K.
Cultural outsiders’ evaluations of (im)politeness in Finland and in France
Authors: Isosävi Johanna
Published: June 2020

Intercultural interaction may be complicated by differing verbal and nonverbal displays of (im)politeness. Yet cultural outsiders’ evaluations of (im)politeness have not been widely examined. To fill this gap, this study investigated perceptions of Finnish politeness among French people living in Finland and perceptions of French politeness among Finns currently or previously living in France. Focus groups were used in order to study culturally shared (im)politeness norms and their variations. Based on a dialogical discourse analysis of five focus group discussions, it is argued that personal space emerges as a salient factor for politeness in Finland, while verbal and nonverbal rapport is more important in France. These overarching themes - personal space and rapport - led to discussions about greetings, silence and holding doors open. Greeting and opening doors appeared more categorical in France, while silence was better tolerated in Finland. In addition to dominant norms, regional and individual variations were reported. Overall, (im)politeness norms appeared to be vaguer in Finland than in France. Building upon this study, future research should examine if changes emerge in Finnish (im)politeness norms related to rapport or if space remains more valued.
Towards an emic understanding of Mianzi giving in the Chinese context
Authors: Li Hui
Published: June 2020

Face-giving is an understudied notion among the studies of face and facework. This article aims to enhance the understanding of the concept by exploring how the first-order concept of mianzi giving is understood by native members. By examining native discourses in which mianzi giving is explicitly mentioned, we find that in addition to being based on the actor’s intention or the recipient’s feeling, the interpretation of mianzi giving can also be based on the interpersonal consequence of an act grounded in the understanding of the (meta)participant, who takes the footing of the author in the Goffmanian sense. In the (meta)participant’s understanding, mianzi giving is understood as a marked and favorable alternative act with reference to the empirical or moral parameter evoked in the local interaction.
First archaeological investigations of barrows in the Bačka region and the question of the Eneolithic/Early Bronze Age barrows in Vojvodina
Authors: Koledin Jovan , Bugaj Urszula , Jarosz Paweł , Novak Mario , Przybyła Marcin M. , Podsiadło Michał , Szczepanek Anita , Spasić Miloš , Włodarczak Piotr
Published: June 2020

In various prehistoric periods, the territory of Vojvodina became the target of the migration of steppe communities with eastern origins. The oldest of these movements are dated to the late Eneolithic and the beginning of the Early Bronze Age. There are at least two stages among them: I – dated to the end of the fourth millennium BC / beginning of the third millennium BC and II – dated from 3000 to 2600 BC and combined with the communities of the classical phase of the Yamnaya culture. The data documenting these processes have been relatively poor so far – in comparison with the neighboring regions of Bulgaria, Romania and Hungary. A big drawback was the small number of systematically excavated mounds, providing comprehensive data on the funeral ritual of steppe communities. This poor database has been slightly enriched as a result of the design of the National Science Centre (Cracow, Poland) entitled “Danubian route of the Yamnaya culture”. Its effect was to examine the first two barrows located on the territory of Bačka – the western region of Vojvodina. Currently, these burial mounds are the westernmost points on the map of the cemeteries of the Yamnaya culture complex. Radiocarbon dates obtained for new finds, as well as for archival materials, allow specifying two stages of use of cemeteries of Yamnaya culture: I – around 3000–2900 BC and II – around 2800–2600 BC. Among the finds from Banat, there were also few materials coming probably from the older period, corresponding to the classical phase of Baden – Coţofeni I–II. The enigmatic nature of these discoveries, however, does not allow to specify their dating as well as cultural dependencies.
HIV Risk Behaviors in Relation to Psychosocial Factors and Internet Usage Among Asian and Pacific Islander (API) Men Who Had Sex With Men (MSM) in California
Authors: Nemoto Tooru , Xie Hui , Iwamoto Mariko , Sakata Maria
Published: June 2020

Very few studies have been conducted to investigate HIV risk and protective behaviors in relation to psychosocial factors among Asian and Pacific Islander (API) MSM whose HIV/AIDS prevalence is lower than those of other racial/ethnic groups. This study, based on an online survey targeting API MSM in California revealed that API MSM often met sex partners online and that psychosocial factors (e.g., homophobia and identity with API gay community) were correlated with condomless receptive anal sex (RAS) with casual partners. In particular, an Asian cultural construct, interdependency, was correlated with condom use for RAS; that is, those who consider sex partners' health and value harmony tend to engage in safe sex. This finding sheds light on re-thinking the current over-emphasis on assertiveness and self-responsibility to keep free from HIV/STIs during negotiation with partners. Future STI prevention programs for API MSM should incorporate Asian cultural constructs and target specific risk groups.
Identifying Community-Informed Language to Promote HIV Pre-exposure Prophylaxis (PrEP) in Black LGBTQ Communities in Baltimore
Authors: Fields Errol L. , Long Amanda , Bademosi Kehinde , Granderson Ricky , Schumacher Christina M. , Chandran Aruna , Kingon Yvonne , Jennings Jacky M.
Published: June 2020

LGBTQ populations, particularly Black men who have sex with men and transgender women, experience significant HIV disparities; public health messages may inadvertently stigmatize LGBTQ populations. We sought to use qualitative methods to inform a PrEP campaign. Unstructured focus groups were conducted among predominantly Black LGBTQ persons recruited through social media and events. Discussions were audio-recorded, transcribed, and analyzed in NVivo using categorical analysis. Eighty individuals participated in 13 focus groups; 80% (64) identified as sexual or gender minorities. Eighty-eight percent (70) identified as Black/African American. Four themes emerged: (1) culturally competent, community-informed, locally relevant messaging, (2) avoiding stigmatizing language or images, (3) inaccessibility of clinical language, and (4) using identity labels representing local communities and their diversity. Findings suggest PrEP campaigns need to be developed through community-informed processes to engage and avoid stigmatizing priority populations. Ongoing partnerships between public health and LGBTQ communities can facilitate development of campaigns with engaging, acceptable language.
Mental Health Support in the Perinatal Period for Women With a Personality Disorder Diagnosis: A Qualitative Study of Women's Experiences
Authors: Zacharia Alice , Taylor Billie Lever , Sweeney Angela , Morant Nicola , Howard Louise M. , Johnson Sonia
Published: June 2020

Women who receive a diagnosis of personality disorder may face particular challenges in the context of having a baby. However, this area has received little attention. This study aimed to qualitatively explore experiences of mental health support during the perinatal period in a group of mothers who self-reported having a personality disorder diagnosis. Semistructured interviews were conducted with 12 women who received mental health support during the perinatal period. These data were analyzed thematically. Key themes related to women feeling judged to be unfit mothers; not feeling heard or understood by services; feeling that services struggled with the complexity of their needs; valuing specialist support to cope with their struggles in motherhood; and valuing professional relationships that resembled real-life friendships. Our findings raise questions about how best to provide support to this group of women and about the use and consequences of the diagnosis of personality disorder among new mothers.
Reciprocal Influences of Parent and Adolescent Borderline Personality Symptoms Over 3 Years
Authors: Kaufman Erin A. , Victor Sarah E. , Hipwell Alison E. , Stepp Stephanie D.
Published: June 2020

Leading etiological theories implicate the family environment in shaping borderline personality disorder (BPD). Although a substantive literature explores familial aggregation of this condition, most studies focus on parent influence(s) on offspring symptoms without examining youth symptom influence on the parent. The current study investigated reciprocal relations between parent and adolescent BPD symptoms over time. Participants were 498 dyads composed of urban-living girls and their parents enrolled in a longitudinal cohort study (Pittsburgh Girls Study). The authors examined BPD severity scores assessed yearly when youth were ages 15-17 years in a series of cross-lagged panel models. After controlling for autoregressive effects, a measure of parent-child conflict, and an indicator of socioeconomic status, evidence of parental influence on adolescent symptoms did not emerge. However, adolescent BPD symptoms at age 16 predicted greater parent BPD symptoms at age 17 above the influence of depression. Results highlight the importance of considering the influence of youth BPD on parental symptoms.
Progress in Treatment of Myocardial Injury in Patients with 2019-nCoV: A Chinese Experience
Authors: Wei Shixiong , Zhang Lin , Cui Huimin , Jiang Shengli
Published: June 2020

Since December 2019, the 2019 novel coronavirus (2019-nCoV) infection began to appear in Hubei Province of China and gradually spread to other provinces and other countries. The virus has the characteristics of strong transmission capacity, diverse clinical manifestations, long incubation period, and latent infection, thus posing a serious threat to human life safety and health. With the increasing number of cases and the continuous enrichment of clinical data, 2019-nCoV–infected patients have received more and more attention regarding myocardial injury related to virus infection besides typical respiratory system manifestations. According to the published data, we summarize the myocardial injury manifestations, characteristics, effects on disease condition, and prognosis of 2019-nCoV–infected patients and discuss the possible injury mechanism, treatment methods, and future research directions.