bluuebunny/crossref_metadata_2025 huggingface dataset:
Un acto de deseo irremediable: el onanismo en la poesía contemporánea y en español escrita por mujeres
Authors: Moya Micaela
Published: October 2022

A lo largo de la historia de la literatura, la mujer ha sido fundamentalmente musa de la poesía amatoria masculina. A partir de la década del ochenta, se observa en la poesía en español un fuerte auge del erotismo en clave femenina. Este trabajo se propone estudiar, entre las formas del erotismo femenino en la poesía, particularmente una: el onanismo. Tomando como punto de partida la aproximación que realiza a esta temática Luna Miguel en El dedo (2016) y Caliente (2021), se analizarán los poemas citados por la propia Miguel (Sexton, Rosal, Román Marroquín), pero, además, se añadirán a su corpus otros textos poéticos que, anteriores a los de las poetas más jóvenes citadas por Miguel, abordan la masturbación femenina (Peri Rossi, Rossetti, Galaz, Parra). El fin del trabajo será no solo poner de manifiesto la existencia y recurrencia de esta temática en la poesía de mujeres sino también evaluar las distintas imágenes que se proyectan en relación con la práctica en los textos.
Pacto de silencio: expresiones de la culpa en Derecho natural (2017) y Fin de temporada (2020) de Ignacio Martínez de Pisón
Authors: García Ponce David
Published: October 2022

Ignacio Martínez de Pisón describe en sus novelas un retrato de la Transición española basado en la experiencia de los que no estuvieron en primera fila y que, sin embargo, fueron testigos de los cambios políticos y sociales acaecidos. En esta línea, el autor relata historias familiares donde quedan reflejadas las emociones que desarrollan los personajes: una de ellas es la culpa. Debido a la relevancia de esta en la narrativa del escritor, en este artículo nos proponemos analizar su presencia en las dos últimas novelas de ficción publicadas por el autor: Derecho natural (2017) y Fin de temporada (2020). Para tal objetivo, analizamos las diversas formas de representación de culpabilidad a través de dos ejes diferentes: el retrato psicológico de los personajes y los ambientes narrativos de ambas obras.
An Investigation of Learning English as a Second Language in Korea
Authors: Richter Nicholas E.
Published: October 2022

Purpose: Decades of literature have described that learning English as a second language (ESL) is an important yet difficult undertaking for Korean university students. This study investigated, from an educational and social perspective, student perceptions on how they learned, comprehended, communicated, and used ESL.Methods: An exploratory descriptive method used conclusions from the literature followed by interviews with 14 students from different universities examined factors they perceived impacted the ability and confidence with the acquisition of basic English language skills.Results: Learning English as a second language (ESL) is influenced by choices in approaches to student learning. Interviewees reflected on their personal experiences and reported on different approaches within programs for learning English as a second language. The emergent categories and themes highlighted challenges at each educational level, as well as the influence of Korean cultural factors and social issues on learning outcomes. The latter are confined to meeting examination requirements rather than listening skills and comprehension that would achieve fluency in ESL.Conclusion: Given the importance that listening comprehension plays in Korean students’ achievement of fluency in the English language, it is suggested ESL teachers could integrate more active learning approaches and methodologies into their teaching/learning approaches to assist competence and confidence with English conversation would overcome problems arising from the difference between Korea’s first and second languages.
Evaluación de la fenología de la Cinchona officinalis L. en la zona de amortiguamiento del bosque de protección de Pagaibamba
Authors: Marcelo-Bazán Fátima E. , Baselly-Villanueva Juan R.
Published: October 2022

El objetivo del presente estudio fue evaluar la fenología de la Cinchona officinalis L. en la zona de amortiguamiento del bosque de protección de Pagaibamba. Para lo cual se seleccionaron individuos de quina teniendo en cuenta criterios básicos de selección. Se instalaron ocho parcelas circulares de 12.5 m de radio y se seleccionó 10 árboles referenciales ubicados en áreas agropecuarias, evaluándose en total 22 individuos. Las evaluaciones se realizaron de forma mensual entre el periodo de junio de 2016 a mayo de 2017. Los resultados encontrados muestraron que la tendencia de las fenofases entre los árboles referenciales ubicados en áreas agropecuarias y los árboles en las parcelas fenológicas ubicadas en áreas boscosas fue la misma, en la etapa fenológica de foliación se encontró la máxima formación de hojas durante el mes de agosto y su maduración en octubre, mientras que la defoliación fue constante. La etapa fenológica de floración inició en enero y alcanzó el pico en junio. La etapa fenológica de fructificación se presentó en julio y maduró en septiembre llegando a la etapa dehiscente en octubre. La quina es una especie perenifólia y que los posibles meses para la colecta de semillas es de septiembre a noviembre.
Megahertz-Rate Imaging of Hypersonic Boundary-Layer Instabilities in a Mach 10 Shock Tunnel
Authors: Jiang Naibo , Hsu Paul S. , Slipchenko Mikhail , Roy Sukesh , Lauriola Daniel K. , Webb Austin M. , Meyer Terrence R. , Gragston Mark , Parker Ron , Portoni Phillip , McDermott Conor , Seitz Kevin , Wadhams Timothy P.
Published: October 2022

The transition of the boundary-layer state from laminar to turbulent on a 7° sharp cone in Mach 10 flow is measured using several high-speed optical diagnostics capable of time-resolved measurements of the second-mode instability with high spatial resolution. Specifically, megahertz-rate nitric oxide planar laser-induced fluorescence (NO PLIF) imaging is done at 1 MHz to provide a non-path-integrated visualization of second-mode associated structures in the transitioning boundary layer. A recent variation of focused laser differential interferometry (FLDI), namely, linear array FLDI (LA-FLDI), is also applied for multipoint measurements of frequency content in the transitioning boundary layer. From each data set, the frequency of the most unstable second-mode instability is obtained along with the phase velocity of the second-mode waves. Measurements show good agreement relative to each other and also with surface pressure sensors and high-speed schlieren imaging. Furthermore, the 1 MHz NO PLIF imaging demonstrated here shows great potential for visualization of transitional and turbulent boundary layers when path-integrated diagnostics cannot be used.
COVID-19 and the ‘New Normal’ in Education: Exacerbating Existing Inequities in Education
Authors: Sayed Yusuf , Singh Marcina , Mort Thelma
Published: October 2022

This paper considers education responses to the COVID-19 pandemic, with specific reference to South Africa, examining how inequality has been exacerbated as a result of the pandemic. It outlines how education policy choices are shaped and how the (mis)use of evidence highlights the lack of meaningful and robust involvement by key education stakeholders and social science specialists, particularly from the critical tradition. COVID-19 has intensified and sharpened social, political and economic fragilities and inequities globally, forcing governments to (re)think responses to social problems and disruptions. This paper underscores three dimensions of inequity in education as a result of the pandemic: equitable teaching and learning during the lockdown and school closures; inequities that may result from the (re)opening of schools in the ‘new normal’; and the lack of attention to psychosocial support and professional development. The paper argues that while this pandemic may be new, it has exacerbated existing inequities in education provision, intensified by the COVID-19 disaster management and education policy. The paper argues for a progressive approach to education transformation in response to this pandemic and future crises and disruptions.
What’s in a Name? Reflections at a Milestone Moment in African Safety Promotion
Authors: Seedat Mohamed
Published: October 2022

The year 2020 marked 19 years since African Safety Promotion: A Journal of Injury and Violence Prevention (ASP) was launched. In this reflective account, I describe selected aspects of the journal’s reach and published contents, with reference to the founding impulse and aims that shaped its vision and trajectory over almost two decades. Even though ASP was successful in its aim of attracting contributions that support the development of public health-oriented injury and violence prevention science, it did not gain the requisite traction with respect to its intention to serve as an Africa-centred dialogical space. Several factors appear to have influenced ASP’s substantive trajectory, identity and progression, and the subsequent decision to change its name.
Literature Review: Generating a South African-Based Theory on the Development of Violent Youth Behaviour in South Africa
Authors: Erasmus Helena Catharina
Published: October 2022

The article is aimed towards guiding the reader along the road I have travelled towards realising the importance of generating South African theories on youth violence for improved violence prevention interventions. The article reflects important insights that I have developed on the way in which the predictability of violence is investigated. These insights revolve around the study of risk and protective factors, the development of models predicting the future occurrence of violence, and theories used to explain the development of youth violence. Challenges identified are that psychological mechanisms are not accounted for when working with risk and protective factors and predictive models, that youth violence is mostly studied under an umbrella term reflecting a collection of youth offences, and that some studies on violent behaviour separate violent behaviour from the context in which it took place. The solution presented is embedded in the generation of theory using the grounded theory methodology, with the aim to redress the challenges to better inform programme theories in prevention programmes for youth violence.
Looting the archive
Authors: Samudzi Zoé
Published: October 2022

Since African nation-states began to gain their independence in the mid-twentieth century, they have fought for the repatriation of cultural artifacts and human remains as an integral part of continental processes of decolonization. Using the concept of the “afterlife of genocide” as a method for understanding transformed but still ongoing processes of genocidal dispossession, this paper engages the relationship between the organizing colonial logics of the 1904-1908 German genocide of Ovaherero and Nama people in South West Africa and the continued presence of Ovaherero and Nama skulls in Euroamerican museum institutions.
Migration, homelessness and internalised displacement
Authors: Asani Furaha , Kinouani Guilaine
Published: October 2022

Discourses of migration tend to be decontextualised from the personal and from the lived experience of displaced peoples. Splitting migrant bodies from land, history and their socio-political realities contributes to the dehumanisation of those who have had to make a home outside borders set by colonialism, whiteness and associated ethno-nationalist violence – often because of the sequelae of colonialism, whiteness and associated ethno-nationalist violence. Engaging with the embodied experience of migrants and situating it within intergenerational contexts of homelessness and displacement is the strategy adopted here to give a name to the nameless and to theorise that which is all too often rendered meaningless, insignificant and, therefore, invisible. In this article, through an auto-ethnographic engagement with our roots in the “heart of Africa” – a part of the world so heavily tainted with blood, mutilation and imperial necropolitics – we reflect on the journey to navigating the hostility, territoriality and dislocation caused by migration. We are two Black African women with complicated and fragmented histories with the continent of Africa. We ask the reader to follow our journeys and that of ‘Others’ as we reflect on the psychological and ontological consequences of border violence and necropolitics. We consider what living at the border of home entails and the various ways of being and thinking we have employed to resist internalised displacement.
Health and Physical Fitness Profiles of Security Guards at an Urban University in South Africa
Authors: Morar Meenal , Coopoo Yoga , Noorbhai Habib
Published: October 2022

In this study, we documented the value and importance of health and fitness of male and female security guards at an urban university in South Africa. We invited 84 participants to determine their health, selected fitness profiles and work readiness. We used four questionnaires, namely the physical activity readiness questionnaire, the medical history questionnaire, the lifestyle evaluation questionnaire, and the heart risk factor questionnaire. These questionnaires assisted with risk factor classification for the study cohort. Health and selected fitness parameters were also tested. Descriptive data were analysed using means and standard deviations for each variable. Comparisons between the male and female participants were made to find any statistically significant differences. A t-test was used to analyse the means between the gender groups. The correlation coefficient was used to determine the relationships between the variables. The results indicate that the female participants were less fit than the male participants; however, the fitness results were similar to the general population, which should be much higher as such occupations require higher levels of fitness. In this study, we provide recommendations for developing health and fitness protocols (for protection service personnel) in the field of health and fitness, and practical implications that can be utilised for both protective personnel and broader society.
Energy Supply Security and Artificial Intelligence Applications
Authors: TÜR MEHMET RIDA
Published: October 2022

There are various options and instruments to ensure energy security, which is very important in terms of accepting energy efficiency as a source of supply and implementing an innovative political perspective. When energy efficiency practices are supported by relatively rich renewable energy resources, it will be possible to reduce the energy import bill. In this process, coal, and nuclear options, as well as renewable energy, may play a prominent role on the supply side. In this context, the necessity of a well-functioning legal system, an independent decision-making authority, and a well-developed accountability institution to make the necessary investments remains important. In integrated cooperation with artificial intelligence, the internet of things, and machine learning technologies, it is possible to store, process, and manage data, which creates energy supply security, with less time and cost. Advanced technology continues to permeate every aspect of the modern world, and the energy industry is no exception. Artificial intelligence has all the capabilities that can radically change or even revolutionize the energy industry. This study predicts that in the near future AI will go from being a useful technological marvel to being the most influential decision-maker in the energy industry.
Pyruvate kinase deficiency: A rare cause of hemolytic anemia: A case report from North-Eastern India
Authors: Kazi Bilal Shoeb , Dolai Tuphan Kanti , Sen Ankita , Das Reena
Published: October 2022

Pyruvate kinase, liver and RBC (PKLR) gene located on chromosome 1q21 encodes erythrocyte pyruvate kinase enzyme. Pyruvate kinase conveys the concluding tread of the glycolytic pathway, along with production of the 50% red cell total adenosine triphosphate. Pyruvate kinase deficiency (PKD) is a rare autosomal recessive disorder causing congenital non-spherocytic hemolytic anemia (CNSH). Biallelic pathogenic variation in the PKLR gene is responsible for PKD. It is the most common glycolytic defect resulting in CNSH. This case report highlights different pathogenic variants in PKLR gene detected in a patient having severe PKD.
GaTewAY : Graph theory-based software for automatic analysis of molecular conformers generated over time
Authors: Bougueroua Sana , Quessette Franck , Barth Dominique , Gaigeot Marie-Pierre
Published: October 2022

GaTewAY is a post-processing tool for molecular dynamics (MD) simulation databased on graph theoretical techniques. The main idea is to construct 2D graphs from the 3D structures. Then, GaTewAY identifies the conformations over time based on the dynamics of bonds and the isomorphism test. The use of graph theory methods/tools does not only provide a direct and fast methodology to identify conformers, but also allows following in time the interconversion reactions between the different conformers as shown by graphs of transitions. In this paper, we describe the methodology used to develop GaTeWAY. Then, we describe the code with its different modules. We present the inputs of GaTeWAY, the threshold values, the usage of the code and the main outputs. Our software has been tested and validated on DFT-MD and QM-MM trajectories of gas phase molecules and clusters. We will, in particular, illustrate results for peptides to have an idea about the outputs. The algorithm's transferability is further demonstrated on a more complex air/liquid water interface. We designed our algorithm so that it can be extended and consider any types of bonds/interactions and parameters; hence, GaTeWAY can be applied to any molecular system. Ongoing work aims to analyze reaction networks in clusters for catalysis. The results are promising. Another manuscript has just been submitted, which illustrates the performance of GateWAY for these systems.
Improved Performance of Positive-ion mode Free Radical-Initiated Peptide Sequencing with para-TEMPO-Bz
Authors: Osho Kemi , Wasik Kimberly , Geary Laina , Borotto Nicholas
Published: October 2022

Free radical-initiated peptide sequencing (FRIPS) is a tandem mass spectrometry (MS/MS) technique that generates sequence informative ions via collisionally-initiated radical chemistry. Collision activation (CA) homolytically cleaves an installed radical precursor, initiates radical formation, extensive hydrogen atom transfer, and peptide backbone dissociation. While FRIPS technique shows great promise, when applied to multiply charged derivatized peptide ions, a series of high abundance mass losses are observed which syphon ion abundance from radically generated sequence ions. This loss of ion abundance reduces the sequence coverage generated by FRIPS fragmentation. In this work, we hypothesized that these mass losses were instigated by the ortho-orientation of the radical precursor undergoing facile conversion into five- or six-membered intermediates and that the para-precursor would not undergo this chemistry. To test this assertion, we synthesized para-TEMPO-Bz, conjugated it to these peptides, and collisionally activated each. And indeed, we see the complete elimination of these undesired collisional processes and the significant increase in radical precursor ion abundance. The increase in ion abundance leads to a significant increase in the sequence coverage generated. These results demonstrate that p-TEMPO-Bz significantly improves the performance of positive-ion mode FRIPS and may be a suitable alternative to the currently utilized ortho-TEMPO-Bz-based FRIPS.
Performance of Density Functionals and Semiempirical 3c Methods for Small Gold-Thiolate Clusters
Authors: Khatun Maya , Paul Sayan , Roy Saikat , Dey Subhasis , Anoop Anakuthil
Published: October 2022

Amid the surge of computational studies of gold thiolate clusters in the recent past, we present a comparison of popular density functionals (DFAs) and three-part corrected methods (3c-methods) on their performance by taking a dataset consisting 18 isomers of Aun(SCH3)m (m ≤ n =1-3) stoichiometry. We have compared the efficiency and accuracy of the DFAs and 3c-methods in geometry optimization with RI-SCS-MP2 and energies with DLPNO-CCSD(T) as reference methods. The lowest energy structure out of the largest stoichiometry from our dataset i.e., Au3(SCH3)3 is considered to evaluate the computational time for SCF and gradient. Alongside, the number of optimization steps to locate the most stable minima of Au3(SCH3)3 are compared to assess the efficiency of the methods. A comparison of relevant bond lengths with the reference geometry was made to estimate the accuracy in geometry optimization. Some methods such as LC-BLYP, ⍵B97M-D3BJ, M06-2X, and PBEh-3c are unable to locate many of the minima that are found by most of the other methods; thus, the versatility in locating various minima is also an important criterion in choosing a method for the given project. We have compared the relative energies among the isomers along every stoichiometric series and the interaction energy of the gold core with the ligands to estimate the accuracy of the methods. The dependence of basis set size and relativistic effects on energies are also compared. Some of the highlights are the following. TPSS shows accuracy, whereas mPWPW is fast with comparable accuracy. The range separated hybrid DFAs are the best choice for the relative energies of the clusters. CAM-B3LYP excels, whereas B3LYP shows poor performance. Overall, LC-BLYP is a balanced performer considering both the geometry and relative stability of the structures, but it lacks diversity. The 3c-methods, although fast, are less impressive in relative stability.
Stacks of a Hidden Treasure: on the Self-Assemble of Perovskite Nanoplates in Organic Solvents
Authors: Moral Raphael , Malfatti-Gasperini Antônio , Bonato Luiz , Vale Brener , Oliveira Cristiano , Nogueira Ana
Published: October 2022

In recent years, perovskite nanocrystal superlattices have been reported with collective optical and electronic quantum phenomena. Regarding perovskite nanoplates, their superlattices can be easily observed on electron microscopy grids, for example, and they too present ensemble optical response. However, little is known on the self-assemble and optical properties of the perovskite nanoplates superlattices in solvents. Here, we report a simple strategy to induce the formation of these nanoplates stacks (1D superlattices) in suspension in different organic solvents. We investigate the influence of concentration and viscosity on their formation. For that purpose, we combined wide- and small-angle X-ray scattering and scanning transmission electron microscopy to evaluate CsPbBr3 and CsPbI3 perovskite nanoplates with different thickness distributions. We found that, in hexane, the concentration threshold for the formation of the aggregated stacks is rather high and approximately 80 mg/mL. In contrast, in decane, dodecane, and hexadecane, we observe a much easier formation of these stacks: the higher is the viscosity, the easier is the stacking of the nanoplates. We, then, discuss the impact of the proximity of the perovskite nanoplates in their colloidal stacks or solid superlattices in terms of Föster resonant energy transfer. We predict an efficiency higher than 50% in the energy transfer even in a low photoluminescence quantum yield scenario for both perovskite compositions.
Global Reactivity Models are Impactful in Industrial Synthesis Applications
Authors: Neves Paulo , McClure Kelly , Verhoeven Jonas , Dyubankova Natalia , Nugmanov Ramil , Gedich Andrey , Menon Sairam , Shi zhicai , Wegner Jörg
Published: October 2022

Artificial Intelligence is revolutionizing many aspects of the pharmaceutical industry. Deep learning models are now routinely applied to guide drug discovery projects leading to faster and improved findings, but there are still many tasks with enormous unrealized potential. One such task is the reaction yield prediction. Every year more than one fifth of all synthesis attempts result in product yields which are either zero or too low. This equates to chemical and human resources being spent on activities which ultimately do not progress the programs, leading to a triple loss when accounting for the cost of opportunity in time wasted. In this work we pre-train a BERT model on more than 16 million reactions from 4 different data sources, and fine tune it to achieve an uncertainty calibrated global yield prediction model. This model is an improvement upon state of the art not just from the increase in pre-train data but also by introducing a new embedding layer which solves a few limitations of SMILES and enables integration of additional information such as equivalents and molecule role into the reaction encoding, the model is called BERT Enriched Embedding (BEE). The model is benchmarked on an open-source dataset against a state-of-the-art synthesis focused BERT showing a near 20-point improvement in r2 score. The model is fine-tuned and tested on an internal company data benchmark, and a prospective study shows that the application of the model can reduce the total number of negative reactions (yield under 5%) ran in Janssen by at least 34%. Lastly, we corroborate the previous results through experimental validation, by directly deploying the model in an on-going drug discovery project and showing that it can also be used successfully as a reagent recommender due to its fast inference speed and reliable confidence estimation, a critical feature for industry application.
A Quantum Information Processing Machine for Computing by Observables
Authors: Remacle Francoise , Levine Raphael D.
Published: October 2022

A quantum machine that accepts an input and processes it in parallel is described. The logic variables of the machine are not wavefunctions (qubits) but observables (i.e., operators) and its operation is decribed in the Heisenberg picture. The active core is a solid-state assembly of small nanosized colloidal quantum dots(QDs) or dimers of dots. The size dispersion of the nanodots that causes fluctuations in their discrete electronic energies is a limiting factor. The input to the machine is provided by a train of very short in time laser pulses, at least four in number. The coherent band width of each ultrashort pulse needs to span at least several and preferably all the single electron excited states of the dots. The spectrum of the QD assembly is measured as a function of the time delays between the input laser pulses. The dependence of the spectrum on the time delays is Fourier transformed to a frequency spectrum. This spectrum of a finite range in time is made up of discrete pixels. These are the visible, raw, basic logic variables. The spectrum is analyzed to determine a possibly smaller number of principal components. A Lie-algebraic point of view is used to explore the use of the machine to emulate the dynamics of other quantum systems. An explicit example demonstrates the considerable quantum advantage of our scheme.
Assessments of Variational Autoencoder in Protein Conformation Exploration
Authors: Xiao Sian , Song Zilin , Tian Hao , Tao Peng
Published: October 2022

Molecular dynamics (MD) simulations have been extensively used to study protein dynamics and subsequently functions. However, they are unable to sufficiently explore the conformational space within equilibrium timescales. The purpose of this study is to evaluate the feasibility of using variational autoencoders to assist the exploration of protein conformational landscapes. Using three modeling systems, we show that variational autoencoders are capable of capturing high-level hidden information which distinguishes alternate protein conformations, which can be readily used for generating unseen and physically plausible protein conformations to direct sampling to favored conformational spaces. Based on our investigations, we also find that VAE prefers interpolation than extrapolation and increasing latent space dimension can lead to a trade-off between performances and difficulties, thus we propose that the initial data preparation is important for building VAE models to explore protein conformational landscapes.
Synthesis and Biological Evaluation of tert-Butyl Ester and Ethyl Ester Prodrugs of L-γ-Methyleneglutamic Acid Amides for Cancer
Authors: Khan Md Imdadul , Mahdi Fakhri , Penfornis Patrice , Akins Nicholas , Hossain Md Imran , Kim Seong Jong , Sulochana Suresh , Adam Amna , Tran Tristan , Tan Chalet , Claudio Pier Paolo , Paris Jason , Le Hoang
Published: October 2022

In cancer cells, glutaminolysis is the primary source of biosynthetic precursors. Recent efforts to develop amino acid analogues to inhibit glutamine metabolism in cancer have been extensive. Our lab recently discovered many L-γ-methyleneglutamic acid amides that were shown to be as efficacious as tamoxifen or olaparib in inhibiting the cell growth of MCF-7, SK-BR-3, and MDA-MB-231 breast cancer cells after 24 or 72 h of treatment. None of these compounds inhibited the cell growth of nonmalignant MCF-10A breast cells. These L-γ-methyleneglutamic acid amides hold promise as novel therapeutics for the treatment of multiple subtypes of breast cancer. Herein we report our synthesis and evaluation of two series of tert-butyl ester and ethyl ester prodrugs of these L-γ-methyleneglutamic acid amides and the cyclic metabolite and its tert-butyl esters and ethyl esters on the three breast cancer cell lines MCF-7, SK-BR-3, and MDA-MB-231 and the nonmalignant MCF-10A breast cell line. These esters were found to suppress the growth of the breast cancer cells, but they were less potent compared to their parent L-γ-methyleneglutamic acid amides. Pharmacokinetic (PK) studies were carried out on the lead L-γ-methyleneglutamic acid amide to establish tissue-specific distribution and other PK parameters. Notably, this lead compound showed moderate exposure to the brain with a half-life of 0.74 h and good tissue distribution, such as in the kidney and liver. Therefore, the L-γ-methyleneglutamic acid amides were then tested on glioblastoma cell lines BNC3 and BNC6 and head and neck cancer cell lines HN30 and HN31. They were found to effectively suppress the growth of these cancer cell lines after 24 or 72 h of treatment in a concentration-dependent manner. These results suggest broad applications of the L-γ-methyleneglutamic acid amides in anticancer therapy.
GOVERNMENT PROGRAM IN UKRAINE AND THE MEMBER STATES OF THE EUROPEAN UNION: COMPARATIVE AND LEGAL ASPECT
Authors: Zubenko Hanna
Published: October 2022

Introduction. The article is devoted to the study of the peculiarities of the normative-legal consolidation of the government program in the member states of the European Union and Ukraine. Emphasis is placed on the issue of constitutional and legal regulation of interaction between the parliament and the government in terms of development and approval of the government program. The purpose of the study is to reveal the constitutional nature of the government program in Ukraine and the мember states of the European Union on the basis of legislation. To solve the set goals and objectives, such research methods as logical-semantic, system-structural, formal-legal, comparative-legal, historical-legal, etc. were used.

Summary of the main research results. The legal nature of the government program of activities is considered. Emphasis is placed on the specifics of enshrining in the constitutions of individual member states of the European Union this document of the highest executive body, the obligation to submit it to parliament and its approval. The article analyzes the legal positions on the classification of the above states into those in which the approval of the government program is one of the conditions for its formation and further operation and those where the procedure of government formation does not depend on approval or disapproval of its program. The consolidation of certain issues concerning the Program of Activities of the Cabinet of Ministers of Ukraine in the Constitution of Ukraine is analyzed. The main stages of the procedure of approving the Program of Activities of the government by the Verkhovna Rada of Ukraine are revealed.

Conclusions. It was emphasized that there are a number of unresolved issues regarding the approval of the Program of Activities of the Cabinet of Ministers of Ukraine by the Verkhovna Rada of Ukraine, which should be resolved by amending the legislation. Relevant amendments to the Constitution of Ukraine and laws of Ukraine on the need for approval by the Verkhovna Rada of Ukraine of the Program of Activities of the Cabinet of Ministers of Ukraine at the stage of its formation have been proposed.
LEGAL REMEDIES FOR LAND RIGHTS AFFECTED BY ACQUISITION TO THE CONSTRUCTION OF PERMANENT HOUSING FULFILLING THE NEED FOR POST-EARTHQUAKE SHELTER IN PALU
Authors: Suwardi  , Pradipta Auriga
Published: October 2022

Basically, the state has the authority to regulate the use of land rights in the territory of Indonesia. However, the problem that often occurs is the disagreement between the Land Acquisition Committee and the holders of land rights in determining the amount of compensation, resulting in problems such as what happened in Palu after the earthquake which flattened housing buildings and required a plot of land for housing construction. Therefore, the aim of this research is to explore legal efforts for land rights that are affected by the acquisition for the construction of permanent housing to meet housing needs after the earthquake in Palu. The research method that used is legal research, while the approach used in this research is statute approach. The results of data analysis show the legal action of land rights holders that are affected by land acquisition for the construction of permanent housing by means of certificate cancellation, the cancellation of the certificate is based on law. Land acquisition for the public interest, including the interests of the nation and the State as well as the common interest of the people, can revoke land rights by giving compensation.
STRATEGIC DEVELOPMENT OF THE BANK UNDER EFFECTIVE CORPORATE GOVERNANCE
Authors: Kochorba Valeriia , Panshun Volodumur
Published: October 2022

The development strategy is the conceptual basis of any business, which determines the priorities in the process of making key decisions to ensure the competitiveness of the organization. The development of common scientific approaches to the content and methodology of the development strategy of Ukrainian banks and its individual functional components is becoming more important in solving the problem of increasing the competitive potential of banking institutions compared to leading foreign banks and banks with foreign capital operating in Ukraine.
Banks, in an effort to maximize their profits, may prefer speculative operations by placing their assets in high-risk instruments, which can lead to a loss of liquidity and solvency. This leads to an increase in the responsibility of the bank's management to determine the strategic goals of financial development of the institution, which should meet current trends in the level of competition in the banking services market in general and its individual segments in particular. Under these circumstances, the role and importance of theoretical and practical aspects of the formation of the bank's strategy, which determines the objectives of financial management and vectors of financial development.
The theoretical principles of corporate culture and compliance of the organization were considered in the work. The strategic development of the banking institution under the conditions of forming an effective corporate policy was presented; the practice of applying effective risk management by banks of Ukraine in compliance with their internal compliance procedures has been studied.
The article analyzes the procedure of observance of corporate culture by banks of Ukraine with the study of performance indicators and their impact on the overall riskiness of the bank. Ratings of domestic banks, their missions, slogans and key aspects of corporate culture in 2021 are presented. The stability of domestic banks is analyzed on the basis of asset quality assessment and stress testing conducted by the National Bank of Ukraine in 2021.
The conclusions provide projected expectations of strategies for further development of public and private sector banks until 2024. The most profitable and unprofitable banks of Ukraine according to the results of 2021 are presented.
INFRASTRUCTURAL ASSURANCE OF THE MECHANISM FOR REGULATING IMBALANCES IN THE MOVEMENT OF FINANCIAL RESOURCES OF THE UKRAINIAN ECONOMY IN THE CONTEXT OF EXTERNAL FLUCTUATIONS
Authors: Zhytar Maksym , Samorodov Borys
Published: October 2022

The article proves that the state regulation of negative manifestations in the functioning of the financial architecture of the national economy is carried out on the basis of a list of effective instruments of national financial policy, directly fiscal and monetary. It is determined that the subjects of ordinary state regulation of the financial architecture of the national economy are the National Bank of Ukraine, the National Commission on Securities and Stock Market, other regulatory bodies (such as the Antimonopoly Committee of Ukraine and the Ministry of Finance of Ukraine and others). It is proposed to include in the goals of such regulation: protection of socio-economic interests of potential participants in financial architecture; equal access of relevant market participants to various components of the financial architecture; support of healthy competition in the financial market, level of transparency and openness, gradual integration into the international financial architecture. It is concluded that the presented strategic directions for state regulation of negative manifestations in the functioning of the financial architecture of the national economy are aimed at forming a reliable system for protecting the rights of investors, as well as protecting socio-economic interests of relevant consumers of financial services. The regulatory mechanism is presented, under which we propose to understand the interconnected system of subjects, forms, instruments and objects of financial market regulation, which operates to achieve sustainable development of financial architecture and all its components, which is generally aimed at improving the sustainability of national economy.
INSTRUMENTAL PRINCIPLES OF INTELLECTUAL CAPITAL ANALYSIS OF SOCIO-ECONOMIC SYSTEMS
Authors: Morozova Nadiia , Novikova Tetyana , Khrystoforova Olena , Malafeyev Timur
Published: October 2022

The article offers the latest approaches to assessing the level of intellectual capital of socio-economic systems based on models and methods of assessing intellectual capital. Modern tools for modeling are applied, namely: methods of reducing information space to assess the overall level of intellectual capital of Ukraine; model of forecasting the level of intellectual capital of Ukraine using adaptive forecasting methods; system-dynamic modeling. Models of intellectual potential assessment are systematized and analyzed according to the following approaches: by analogy with the calculation of the index of human potential development; by functional structure or components of intellectual capital; according to the process approach, which involves determining the input parameters of intellectual capital, indicators that reflect the intellectual processes during the study, and output parameters that represent the final results; by a step-by-step approach based on a step-by-step assessment of intellectual capital.
The aim of the study is to develop a set of models for assessing and analyzing the intellectual capital of socio-economic systems at the macro level, in particular, at the state level, which will improve the quality of formation and management decisions in public relations. To achieve this goal, the article proposes and solves the following scientific tasks: a model for assessing the level of intellectual capital of Ukraine has been built; the model of forecasting of indicators of the intellectual capital of the state has been developed; a simulation model of intellectual capital management of Ukraine has been developed.
The results obtained from the set of models can be used in the formation and adoption of management decisions to improve the efficiency of intellectual capital of Ukraine and the development of strategies for safe development of human resources by state and regional governments.
DETERMINATION OF PROSPECTIVE DIRECTIONS FOR IMPROVEMENT OF CASHLESS CALCULATIONS AND THEIR STANDARDIZATION FOR THE UKRAINIAN PAYMENTS MARKET
Authors: Bitner Irina , Viazovyi Serhii
Published: October 2022

The current state of the banking system takes place in conditions of high competition and rapid development of innovative innovations in the field of payments. Secure and efficient payments are crucial for users, banks and the economy as a whole. That is why an important and urgent task for the state and the banking system is to understand and form a clear course for the introduction of new types of calculations. Today, the trend is non-cash payments that are increasingly pushing cash out of circulation.

The paper describes the definition of "non-cash payments" and their functioning in the light of national experience. The process of regulation of settlements by the regulatory framework in Ukraine was considered. An analysis of the self-regulation of the payment industry and the principles of its implementation in foreign countries was conducted.

The current state of non-cash payments in banks and financial institutions of Ukraine is given.

The article considers new forms of non-cash payments that are already used abroad in developed countries and the possibility of their introduction and standardization in the Ukrainian financial and banking sector.

An analysis of the state of use of plastic payment cards and modernization in Ukraine was conducted. Different types of PoS-terminals are also characterized and their comparative characteristics are carried out.

The possibility of using non-cash payments using mobile devices and the Internet has been studied. The use of telephones for payment has led to significant changes in the systems of receiving and transmitting money over the Internet. In turn, there is a problem, which is that not everywhere you can access the network to make payments. In this regard, the world's leading countries use the USSD service.

The analysis of the impact of positive and negative aspects of the use of new types of non-cash payments and analyzes their impact on the economic condition of Ukraine after the introduction of these opportunities in the banking market.

The paper presents the impact of the demographic situation and customer habits on the use of non-cash payments in Ukraine.
Revija Les/Wood izhaja pod okriljem Založbe Univerze v Ljubljani
Authors: Rudolf Matevž
Published: October 2022

Univerza v Ljubljani je s 40.000 študentkami in študenti največja in najstarejša univerza v Sloveniji. Sestavlja jo kar 26 fakultet in akademij in pokriva vsa znanstvena področja. Posledično je bogata tudi njena založniška dejavnost, ki pa je zelo razvejana. Konec študijskega leta 2019/2020, ko je Univerza praznovala 100. obletnico, so se uresničile dolgoletne želje, da bi Univerza dobila skupno založbo. Nastala je Založba Univerze v Ljubljani (University of Ljubljana Press), ki s svojevrstno organiziranostjo povezuje založniško dejavnost na fakultetah in akademijah. Osnova Založbe UL sicer ostaja založniška dejavnost na članicah UL, pomemben korak pa smo naredili z začetkom izdajanja publikacij pod skupnim imenom Založba UL. Ko bo ta proces v celoti končan, bo šele res razvidno, da je Založba UL ena večjih evropskih univerzitetnih založb, ki letno izdaja več kot 250 monografij.

V okviru Univerze v Ljubljani izhaja tudi 50 mednarodnih znanstvenih revij. Skoraj vse revije izhajajo v odprtem dostopu, kar pomeni, da so članki dostopni takoj po izidu posamezne številke. Ker so bile do pred kratkim revije objavljene na najrazličnejših naslovih in platformah, je Založba UL vzpostavila skupni spletni portal Revije UL. Portal temelji na odprtokodnem sistemu Open Journals Systems, ki poleg objave posameznih člankov v ozadju omogoča tudi vse potrebne založniške korake za urednikovanje (elektronsko sprejemanje člankov, posredovanje člankov recenzentom, oblikovalcem, lektorjem itd.). Portal je dostopen na naslovu https://journals.uni-lj.si/. Na portalu trenutno gostuje 19 revij, objavljenih pa je več kot 6.500 člankov.

Ena izmed takih revij je tudi revija Les/Wood, ki od leta 2017 dvakrat letno izhaja z odprtim dostopom po diamantnem modelu. Revija sicer nadaljuje zapuščino revije Les: revija za lesno gospodarstvo, ki je neprekinjeno izhajala med leti 1949 in 2013. Revija obravnava širše področje lesarstva in z lesarstvom povezana področja, teme, ki so še kako pomembne za trajnostno naravnan odnos do današnjega sveta. Les je namreč edina obnovljiva surovina, ki jo imamo v Sloveniji v izobilju, zato je še toliko bolj pomembno, da tudi preko znanstvenih člankov podpiramo poglobitev znanj o lesu in lesnih kompozitih ter sodobnih tehnologijah za predelavo in obdelavo lesa, hkrati pa tudi spodbujamo raziskave o konstruiranju in oblikovanju ter gospodarjenju z lesom in lesnimi proizvodi. Sedež uredništva revije Les/Wood je na Biotehniški fakulteti Univerze v Ljubljani, z letom 2021 pa je revija začela izhajati pod imenom Založbe Univerze v Ljubljani. Verjamemo, da bo s tem korakom revija Les/Wood pridobila večjo mednarodno prepoznavnost in tako še okrepila svojo interdisciplinarno naravnanost.

Uredništvu revije Les/Wood na tem mestu izrekam pohvale za vse opravljeno delo, zaradi katerega revija dosega visoke akademske založniške standarde. S skupnimi močmi bomo tako še bolj spodbudili globalno izmenjavo znanja in tako pripomogli k bolj trajnostnemu razvoju sodobnega sveta.
Problems and Countermeasures of Educational Management of Postgraduates in Colleges and Universities
Authors: Zhang Haiyun , Zhu Yi
Published: October 2022

With the rapid development of postgraduate education in China, the number of postgraduate students in school shows a trend of continuous growth. The postgraduate education management system in most of the colleges and universities has been gradually improved, and it is the primary task of contemporary postgraduate education administrators to cultivate high-level innovative talents who are suitable for the country’s social and economic development. This study analyzed the existing problems in the management of postgraduate education in colleges and universities, and the relevant solutions of the problems were also proposed in this paper.
Relações entre os indícios de Pensamento Matemático Avançado e a aprendizagem interpretadas a partir de pesquisas na licenciatura em Matemática
Authors: Inarejos Osvaldo , Savioli Angela Marta Pereira das Dores
Published: October 2022

Este artigo apresenta resultados de um levantamento de pesquisas fundamentadas no referencial teórico do Pensamento Matemático Avançado (PMA) no contexto da licenciatura em Matemática, que resultou em um corpus de dezessete estudos que utilizaram o referencial teórico do PMA para verificar indícios de pensamento matemático em produções de estudantes. A partir da análise desse corpus, procurou-se entender como essas pesquisas relacionam a aprendizagem em Matemática com os indícios de pensamento matemático. São apresentadas concepções diferentes, mas não contraditórias, tais como: que a aprendizagem pode ser avaliada pelo desenvolvimento do PMA; que o PMA é necessário para a aprendizagem de Matemática Avançada e que o referencial teórico do PMA pode auxiliar o professor a diagnosticar dificuldades e contribuir para a aprendizagem de seus alunos.