bluuebunny/crossref_metadata_2025 huggingface dataset:
Thermally induced crystallization in NbO2 thin films
Authors: Zhang Jiaming , Norris Kate J. , Gibson Gary , Zhao Dongxue , Samuels Katy , Zhang Minxian Max , Yang J. Joshua , Park Joonsuk , Sinclair Robert , Jeon Yoocharn , Li Zhiyong , Williams R. Stanley
Published: September 2016

Niobium dioxide can exhibit negative differential resistance (NDR) in metal-insulator-metal (MIM) devices, which has recently attracted significant interest for its potential applications as a highly non-linear selector element in emerging nonvolatile memory (NVM) and as a locally-active element in neuromorphic circuits. In order to further understand the processing of this material system, we studied the effect of thermal annealing on a 15 nm thick NbO2 thin film sandwiched inside a nanoscale MIM device and compared it with 180 nm thick blanket NbOx (x = 2 and 2.5) films deposited on a silicon dioxide surface as references. A systematic transmission electron microscope (TEM) study revealed a similar structural transition from amorphous to a distorted rutile structure in both cases, with a transition temperature of 700 °C for the NbO2 inside the MIM device and a slightly higher transition temperature of 750 °C for the reference NbO2 film. Quantitative composition analysis from electron energy loss spectroscopy (EELS) showed the stoichiometry of the nominal 15 nm NbO2 layer in the as-fabricated MIM device deviated from the target 1:2 ratio because of an interaction with the electrode materials, which was more prominent at elevated annealing temperature.
Genome-wide identification of multifunctional laccase gene family in cotton (Gossypium spp.); expression and biochemical analysis during fiber development
Authors: Balasubramanian Vimal Kumar , Rai Krishan Mohan , Thu Sandi Win , Hii Mei Mei , Mendu Venugopal
Published: September 2016

The single-celled cotton fibers, produced from seed coat epidermal cells are the largest natural source of textile fibers. The economic value of cotton fiber lies in its length and quality. The multifunctional laccase enzymes play important roles in cell elongation, lignification and pigmentation in plants and could play crucial role in cotton fiber quality. Genome-wide analysis of cultivated allotetraploid (G. hirsutum) and its progenitor diploid (G. arboreum and G. raimondii) cotton species identified 84, 44 and 46 laccase genes, respectively. Analysis of chromosomal location, phylogeny, conserved domain and physical properties showed highly conserved nature of laccases across three cotton species. Gene expression, enzymatic activity and biochemical analysis of developing cotton fibers was performed using G. arboreum species. Of the total 44, 40 laccases showed expression during different stages of fiber development. The higher enzymatic activity of laccases correlated with higher lignin content at 25 DPA (Days Post Anthesis). Further, analysis of cotton fiber phenolic compounds showed an overall decrease at 25 DPA indicating possible incorporation of these substrates into lignin polymer during secondary cell wall biosynthesis. Overall data indicate significant roles of laccases in cotton fiber development, and presents an excellent opportunity for manipulation of fiber development and quality.
Negative Relationship between Erythropoietin Dose and Blood Lead Level in Patients Undergoing Maintenance Hemodialysis
Authors: Huang Wen-Hung , Hsu Ching-Wei , Weng Cheng-Hao , Lin-Tan Dan-Tzu , Yen Tzung-Hai
Published: September 2016

The adverse effects of increased blood lead levels have been well discussed. Several antioxidant agents have been reported to offer protection from lead toxicity and to reduce blood lead levels (BLL). Given that erythropoietin (EPO) also has antioxidant properties, the aim of this cross-sectional study was to assess the role of EPO and other clinical variables on BLL in hemodialysis (HD) patients. We recruited 931 maintenance hemodialysis (MHD) patients who had undergone HD for at least 6 months and who had ever received blood lead level (BLL) study. Use of erythropoiesis-stimulating agents followed the The National Kidney Foundation Kidney Disease Outcomes Quality Initiative (NKF KDOQI) Clinical Practice Guideline. We estimated demographic, hematological, nutritional, inflammatory, biochemical and dialysis-related data based on this study. In the group with EPO, 7% had high BLL. In the group without EPO, 22% had high BLL. From the stepwise liner regression, urban areas, hemodialysis duration and clearance of urea (KT/Vurea) were positively associated with log BLL. In contrast, diabetes (DM) and monthly EPO dose were negatively associated with log BLL. This study showed that EPO dose might be negatively associated with blood lead levels in patients on maintenance hemodialysis.
Large-scale tissue clearing (PACT): Technical evaluation and new perspectives in immunofluorescence, histology and ultrastructure
Authors: Neckel Peter H. , Mattheus Ulrich , Hirt Bernhard , Just Lothar , Mack Andreas F.
Published: September 2016

Novel techniques, like CLARITY and PACT, render large tissue specimens transparent and thereby suitable for microscopic analysis. We used these techniques to evaluate their potential in the intestine as an exemplary organ with a complex tissue composition. Immunohistochemistry, light sheet- and confocal scanning-microscopy enabled us to follow complex three-dimensional structures, like nerve fibers, vessels and epithelial barriers throughout the entire organ. Moreover, in a systematic electron microscopic study, we analyzed the morphology and preservation of tissue on ultrastructural level during the clearing process. We also connect tissue clearing with classical histology and demonstrate that cleared tissues can be stained with Hematoxylin-Eosin and Heidenhain’s Azan stain, suggesting potential use in histopathology. These experiments showed that a neutral pH during the clearing process results in much better preservation of tissue ultrastructure and standard stainability. Volume changes of specimens were monitored and quantified during the course of the protocol. Additionally, we employed the technique to visualize the enteric nervous system and the epithelial barrier in post mortem human gut preparations. Our data show the high potential of tissue clearing throughout different tissue types supporting its usefulness in research and diagnosis and contribute to the technical discussion of ultrastructural tissue-retention.
Single sample resolution of rare microbial dark matter in a marine invertebrate metagenome
Authors: Miller Ian J. , Weyna Theodore R. , Fong Stephen S. , Lim-Fong Grace E. , Kwan Jason C.
Published: September 2016

Direct, untargeted sequencing of environmental samples (metagenomics) and de novo genome assembly enable the study of uncultured and phylogenetically divergent organisms. However, separating individual genomes from a mixed community has often relied on the differential-coverage analysis of multiple, deeply sequenced samples. In the metagenomic investigation of the marine bryozoan Bugula neritina, we uncovered seven bacterial genomes associated with a single B. neritina individual that appeared to be transient associates, two of which were unique to one individual and undetectable using certain “universal” 16S rRNA primers and probes. We recovered high quality genome assemblies for several rare instances of “microbial dark matter,” or phylogenetically divergent bacteria lacking genomes in reference databases, from a single tissue sample that was not subjected to any physical or chemical pre-treatment. One of these rare, divergent organisms has a small (593 kbp), poorly annotated genome with low GC content (20.9%) and a 16S rRNA gene with just 65% sequence similarity to the closest reference sequence. Our findings illustrate the importance of sampling strategy and de novo assembly of metagenomic reads to understand the extent and function of bacterial biodiversity.
The Golgi associated ERI3 is a Flavivirus host factor
Authors: Ward Alex Michael , Calvert Meredith E. K. , Read Leah R. , Kang Seokyoung , Levitt Brandt E. , Dimopoulos George , Bradrick Shelton S. , Gunaratne Jayantha , Garcia-Blanco Mariano A.
Published: September 2016

Dengue virus (DENV) is a mosquito-borne Flavivirus classified into four serotypes (DENV-1-4) that causes Dengue fever (DF), Dengue hemorrhagic Fever (DHF) or Dengue shock syndrome (DSS). An estimated 390 million people are at risk for infection with DENV and there are no effective vaccines or therapeutics. We utilized RNA chromatography coupled with quantitative mass spectrometry (qMS) to identify host RNA binding proteins (RBPs) that interact with DENV-2 RNA. We identified ERI3 (also PRNPIP and PINT1), a putative 3′–5′ RNA exonuclease, which preferentially associates with DENV-2 genomic RNA via interactions with dumbbell structures in the 3′ UTR. ERI3 is required for accumulation of DENV-2 genomic RNA and production of infectious particles. Furthermore, the mosquito homologue of ERI3 is required for DENV-2 replication in adult Aedes aegypti mosquitos implying that the requirement for ERI3 is conserved in both DENV hosts. In human cells ERI3 localizes to the Golgi in uninfected cells, but relocalizes near sites of DENV-2 replication in infected cells. ERI3 is not required for maintaining DENV-2 RNA stability or translation of the viral polyprotein, but is required for viral RNA synthesis. Our results define a specific role for ERI3 and highlight the importance of Golgi proteins in DENV-2 replication.
Extracting quantum coherence via steering
Authors: Hu Xueyuan , Fan Heng
Published: September 2016

As the precious resource for quantum information processing, quantum coherence can be created remotely if the involved two sites are quantum correlated. It can be expected that the amount of coherence created should depend on the quantity of the shared quantum correlation, which is also a resource. Here, we establish an operational connection between coherence induced by steering and the quantum correlation. We find that the steering-induced coherence quantified by such as relative entropy of coherence and trace-norm of coherence is bounded from above by a known quantum correlation measure defined as the one-side measurement-induced disturbance. The condition that the upper bound saturated by the induced coherence varies for different measures of coherence. The tripartite scenario is also studied and similar conclusion can be obtained. Our results provide the operational connections between local and non-local resources in quantum information processing.
The significance of routine biochemical markers in patients with major depressive disorder
Authors: Peng You-Fan , Xiang Yang , Wei Ye-Sheng
Published: September 2016

The aim of our study is to examine the levels of routine biochemical markers in patients with major depressive disorder (MDD), and combine multiple biochemical parameters to assess the discriminative power for patients with MDD. We used the Hamilton Depression (HAMD) score to evaluate the severity of depressive symptoms in 228 patients with MDD. The phase of depression severity was between moderate and severe in MDD patients. There were significant differences between MDD patients and healthy controls in alanine transaminase (ALT), urea nitrogen (UN), lactate dehydrogenase (LDH), uric acid (UA), total protein (TP), total bile acid (TBA), creatinine (Cr), total bilirubin (Tbil), direct bilirubin (Dbil) and indirect bilirubin (Ibil), high density lipoprotein-cholesterol (HDL-C), fasting blood-glucose (FBG) and fructosamine (SF). Multivariate analysis showed that UN, FBG, HDL-C, SF, TP, Cr and Tbil remained independently association with MDD. Further, a logit equation was established to identify patients with MDD. The composite markers exhibited an area under the curve of 0.810 with cut-off values of 0.410. Our results suggest the associations between UN, FBG, HDL-C, TP, Cr, Tbil, SF and MDD, use of these routine biochemical markers in combination may contribute to improve the complete management for patients with MDD.
Colonization and diversification of the Euphorbia species (sect. Aphyllis subsect. Macaronesicae) on the Canary Islands
Authors: Sun Ye , Li Yanshu , Vargas-Mendoza Carlos Fabián , Wang Faguo , Xing Fuwu
Published: September 2016

Diversification between islands and ecological radiation within islands are postulated to have occurred in the Euphorbia species (sect. Aphyllis subsect. Macaronesicae) on the Canary Islands. In this study, the biogeographical pattern of 11 species of subsect. Macaronesicae and the genetic differentiation among five species were investigated to distinguish the potential mode and mechanism of diversification and speciation. The biogeographical patterns and genetic structure were examined using statistical dispersal-vicariance analysis, Bayesian phylogenetic analysis, reduced median-joining haplotype network analysis and discriminant analysis of principal components. The gene flow between related species was evaluated with an isolation-with-migration model. The ancestral range of the species of subsect. Macaronesicae was inferred to be Tenerife and the Cape Verde Islands and Tenerife-La Gomera acted as sources of diversity to other islands of the Canary Islands. Inter-island colonization of E. lamarckii among the western islands and a colonization of E. regis-jubae from Gran Canaria to northern Africa were revealed. Both diversification between islands and radiation within islands have been revealed in the Euphorbia species (sect. Aphyllis subsect. Macaronesicae) of the Canary Islands. It was clear that this group began the speciation process in Tenerife-La Gomera and this process occurred with gene flow between some related species.
Elevated CO2 increases energetic cost and ion movement in the marine fish intestine
Authors: Heuer Rachael M. , Grosell Martin
Published: September 2016

Energetic costs associated with ion and acid-base regulation in response to ocean acidification have been predicted to decrease the energy available to fish for basic life processes. However, the low cost of ion regulation (6–15% of standard metabolic rate) and inherent variation associated with whole-animal metabolic rate measurements have made it difficult to consistently demonstrate such a cost. Here we aimed to gain resolution in assessing the energetic demand associated with acid-base regulation by examining ion movement and O2 consumption rates of isolated intestinal tissue from Gulf toadfish acclimated to control or 1900 μatm CO2 (projected for year 2300). The active marine fish intestine absorbs ions from ingested seawater in exchange for HCO3− to maintain water balance. We demonstrate that CO2 exposure causes a 13% increase of intestinal HCO3− secretion that the animal does not appear to regulate. Isolated tissue from CO2-exposed toadfish also exhibited an 8% higher O2 consumption rate than tissue from controls. These findings show that compensation for CO2 leads to a seemingly maladaptive persistent base (HCO3−) loss that incurs an energetic expense at the tissue level. Sustained increases to baseline metabolic rate could lead to energetic reallocations away from other life processes at the whole-animal level.
Crystal structures of mono- and bi-specific diabodies and reduction of their structural flexibility by introduction of disulfide bridges at the Fv interface
Authors: Kim Jin Hong , Song Dong Hyun , Youn Suk-Jun , Kim Ji Won , Cho Geunyoung , Kim Sun Chang , Lee Hayyoung , Jin Mi Sun , Lee Jie-Oh
Published: September 2016

Building a sophisticated protein nano-assembly requires a method for linking protein components in a predictable and stable structure. Diabodies are engineered antibody fragments that are composed of two Fv domains connected by short peptide linkers. They are attractive candidates for mediators in assembling protein nano-structures because they can simultaneously bind to two different proteins and are rigid enough to be crystallized. However, comparison of previous crystal structures demonstrates that there is substantial structural diversity in the Fv interface region of diabodies and, therefore, reliable prediction of its structure is not trivial. Here, we present the crystal structures of ten mono- and bi-specific diabodies. We found that changing an arginine residue in the Fv interface to threonine greatly reduced the structural diversity of diabodies. We also found that one of the bispecific diabodies underwent an unexpected process of chain swapping yielding a non-functional monospecific diabody. In order to further reduce structural flexibility and prevent chain shuffling, we introduced disulfide bridges in the Fv interface regions. The disulfide-bridged diabodies have rigid and predictable structures and may have applications in crystallizing proteins, analyzing cryo-electron microscopic images and building protein nano-assemblies.
Assessment of the interaction of Portland cement-based materials with blood and tissue fluids using an animal model
Authors: Schembri Wismayer P. , Lung C. Y. K. , Rappa F. , Cappello F. , Camilleri J.
Published: September 2016

Portland cement used in the construction industry improves its properties when wet. Since most dental materials are used in a moist environment, Portland cement has been developed for use in dentistry. The first generation material is mineral trioxide aggregate (MTA), used in surgical procedures, thus in contact with blood. The aim of this study was to compare the setting of MTA in vitro and in vivo in contact with blood by subcutaneous implantation in rats. The tissue reaction to the material was also investigated. ProRoot MTA (Dentsply) was implanted in the subcutaneous tissues of Sprague-Dawley rats in opposite flanks and left in situ for 3 months. Furthermore the material was also stored in physiological solution in vitro. At the end of the incubation time, tissue histology and material characterization were performed. Surface assessment showed the formation of calcium carbonate for both environments. The bismuth was evident in the tissues thus showing heavy element contamination of the animal specimen. The tissue histology showed a chronic inflammatory cell infiltrate associated with the MTA. MTA interacts with the host tissues and causes a chronic inflammatory reaction when implanted subcutaneously. Hydration in vivo proceeds similarly to the in vitro model with some differences particularly in the bismuth oxide leaching patterns.
Integrative transcriptomic meta-analysis of Parkinson’s disease and depression identifies NAMPT as a potential blood biomarker for de novo Parkinson’s disease
Authors: Santiago Jose A. , Littlefield Alyssa M. , Potashkin Judith A.
Published: September 2016

Emerging research indicates that depression could be one of the earliest prodromal symptoms or risk factors associated with the pathogenesis of Parkinson’s disease (PD), the second most common neurodegenerative disorder worldwide, but the mechanisms underlying the association between both diseases remains unknown. Understanding the molecular networks linking these diseases could facilitate the discovery of novel diagnostic and therapeutics. Transcriptomic meta-analysis and network analysis of blood microarrays from untreated patients with PD and depression identified genes enriched in pathways related to the immune system, metabolism of lipids, glucose, fatty acids, nicotinamide, lysosome, insulin signaling and type 1 diabetes. Nicotinamide phosphoribosyltransferase (NAMPT), an adipokine that plays a role in lipid and glucose metabolism, was identified as the most significant dysregulated gene. Relative abundance of NAMPT was upregulated in blood of 99 early stage and drug-naïve PD patients compared to 101 healthy controls (HC) nested in the cross-sectional Parkinson’s Progression Markers Initiative (PPMI). Thus, here we demonstrate that shared molecular networks between PD and depression provide an additional source of biologically relevant biomarkers. Evaluation of NAMPT in a larger prospective longitudinal study including samples from other neurodegenerative diseases, and patients at risk of PD is warranted.
A comparative study of graphite electrodes using the co-intercalation phenomenon for rechargeable Li, Na and K batteries
Authors: Kim Haegyeom , Yoon Gabin , Lim Kyungmi , Kang Kisuk
Published: September 2016

This work reports the general interplay between guest ions, solvent molecules and graphite host in determining their intercalation characteristics in electrochemical systems.
Enzymatic synthesis and reverse transcription of RNAs incorporating 2′-O-carbamoyl uridine triphosphate
Authors: Masaki Yoshiaki , Ito Hyugo , Oda Yuki , Yamazaki Kazufumi , Tago Nobuhiro , Ohno Kentaro , Ishii Nozomi , Tsunoda Hirosuke , Kanamori Takashi , Ohkubo Akihiro , Sekine Mitsuo , Seio Kohji
Published: September 2016

Enzymatic synthesis and the reverse transcription of RNAs containing 2′-O-carbamoyl uridine were evaluated.
Remarkable catalysis of a wool-like copper electrode for NH3 synthesis from N2 and H2 in non-thermal atmospheric plasma
Authors: Aihara Keigo , Akiyama Mao , Deguchi Takashi , Tanaka Masashi , Hagiwara Rina , Iwamoto Masakazu
Published: September 2016

A copper thin-wire assembly electrode used to produce non-thermal plasma functioned as an efficient catalyst for production of NH3 from N2 and H2 under atmospheric pressure without heating. The NH3 yield was 3.5%.
Synergistic growth factor microenvironments
Authors: Salmerón-Sánchez Manuel , Dalby Matthew J.
Published: September 2016

This paper focuses on developments in materials to stimulate growth factors effects by engineering presentation in synergy with integrins.
Shape-controlled synthesis of CO-free Pd nanocrystals with the use of formic acid as a reducing agent
Authors: Bao Shixiong , Yang Xuan , Luo Ming , Zhou Shan , Wang Xue , Xie Zhaoxiong , Xia Younan
Published: September 2016

This paper reports the use of formic acid as a reducing agent for the shape-controlled synthesis of Pd nanocrystals with no chemisorption of CO on the surface, as confirmed by attenuated total reflection Fourier transform infrared (ATR-FT-IR) spectroscopy.
Molecular dynamics study of di-CF4 based reverse micelles in supercritical CO2
Authors: Liu Bing , Tang Xinpeng , Fang Wenjing , Li Xiaoqi , Zhang Jun , Zhang Zhiliang , Shen Yue , Yan Youguo , Sun Xiaoli , He Jianying
Published: September 2016

Molecular dynamics simulations are performed to investigate the self-aggregation behavior of di-CF4 based reverse micelles in supercritical CO2, and stable and spherical reverse micelles are formed.
Co3(OH)2(HPO4)2 as a novel photocatalyst for O2 evolution under visible-light irradiation
Authors: Zhang Yazhou , Shi Jinwen , Hu Yuchao , Huang Zhenxiong , Guo Liejin
Published: September 2016

Co3(OH)2(HPO4)2 was proved to be a novel visible-light-driven photocatalyst for O2 evolution due to the unique characteristics of Co2+ octahedra.
Two copper(i) cyanide coordination polymers modified by semi-rigid bis(benzimidazole) ligands: syntheses, crystal structures, and electrochemical and photocatalytic properties
Authors: Cui Jing-Wang , An Wei-Jia , Van Hecke Kristof , Cui Guang-Hua
Published: September 2016

Two Cu(i) cyanide complexes with semi-rigid bis(benzimidazole) ligands were synthesized and characterized. Both complexes manifest photocatalytic activities for the degradation of methylene blue.
Exceptional energy and new insight with a sodium–selenium battery based on a carbon nanosheet cathode and a pseudographite anode
Authors: Ding Jia , Zhou Hui , Zhang Hanlei , Stephenson Tyler , Li Zhi , Karpuzov Dimitre , Mitlin David
Published: September 2016

We created a unique sodium ion battery (NIB, SIB) cathode based on selenium in cellulose-derived carbon nanosheets (CCNs), termed Se-CCN.
Design and synthesis of 3-arylbenzopyran based non-steroidal vitamin-D3mimics as osteogenic agents
Authors: Ahmad Mohd. Imran , Raghuvanshi Dushyant Singh , Singh Sarita , John Aijaz A. , Prakash Ravi , Nainawat Kripa Shankar , Singh Divya , Tripathi Shubhandra , Sharma Ashok , Gupta Atul
Published: September 2016

27benhanced osteoblast differentiation at 1 pM in mouse calvarial osteoblast cells without inherent toxicity.
Copper-mediated arylsulfanylations and arylselanylations of pyrimidine or 7-deazapurine nucleosides and nucleotides
Authors: Botha Filip , Slavíčková Michaela , Pohl Radek , Hocek Michal
Published: September 2016

Nucleosides or nucleotides were modified by Cu-mediated arylsulfanylations or -selanylations and used in the enzymatic synthesis of DNA bearing arylsulfanyl or arylselanyl groups.
Narrow bandgap thienothiadiazole-based conjugated porous polymers: from facile direct arylation polymerization to tunable porosities and optoelectronic properties
Authors: Bohra Hassan , Tan Si Yu , Shao Jinjun , Yang Cangjie , Efrem Amsalu , Zhao Yanli , Wang Mingfeng
Published: September 2016

Conjugated porous polymers with narrow bandgaps, tunable morphologies, porosities and optoelectronic properties are synthesized via facile direct arylation polymerization.
One-pot, two-step conversion of alkynes to α-amino (α,α-diamino) ketones with a DMF-activated N-bromoimide strategy
Authors: Li Mengru , Zhang Luyan , Zhao Baozhong , Liang Fushun
Published: September 2016

A simple, one-pot, two-step cascade reaction for the synthesis of α-amino ketones has been developed.
Tackling chemical etching and its mechanisms of polyphenolic composites in various reactive low temperature plasmas
Authors: Puliyalil H. , Filipič G. , Kovač J. , Mozetič M. , Thomas S. , Cvelbar U.
Published: September 2016

We report a systematic study on the selective polymer composite etching and unravelling the mechanisms in various RF gas plasmas.
A facile one-pot multi-component synthesis of novel adamantine substituted imidazo[1,2-a]pyridine derivatives: identification and structure–activity relationship study of their anti-HIV-1 activity
Authors: Tazeem Tazeem , Han Xin , Zhou Qingjun , Wei Jingchen , Tien Po , Yang Guichun , Wu Shuwen , Dong Chune
Published: September 2016

A series of adamantine substituted imidazo[1,2-a]pyridine derivatives were developed through a one-pot multi-component Groebke–Blackburn–Bienaymé reaction, among them several compounds were identified to be the potent inhibitors against HIV-1 cells.
A highly selective and simultaneous determination of ascorbic acid, uric acid and nitrite based on a novel poly-N-acetyl-l-methionine (poly-NALM) thin film
Authors: Kannan Ayyadurai , Sivanesan Arumugam , Kalaivani Govindasamy , Manivel Arumugam , Sevvel Ranganathan
Published: September 2016

This paper demonstrates the facile fabrication of anN-acetyl-l-methionine (NALM) polymer film on a glassy carbon electrode (GCE) by an electropolymerization technique.
The crystal phase transformation of Ag2WO4 through loading onto g-C3N4 sheets with enhanced visible-light photocatalytic activity
Authors: Shi Lei , Gou Jinling , Liang Lin , Wang Fangxiao , Sun Jianmin
Published: September 2016

The morphology and phase of Ag2WO4 were greatly changed through depositing on g-C3N4, enhancing their photocatalytic activity and stability.
Microheterogeneity in binary mixtures of aliphatic alcohols and alkanes: ATR-IR/NIR spectroscopic and chemometric studies
Authors: Wrzeszcz Władysław , Tomza Paweł , Kwaśniewicz Michał , Mazurek Sylwester , Czarnecki Mirosław Antoni
Published: September 2016

This work evidences microheterogeneity and deviation from the ideality in binary mixtures of aliphatic alcohols and alkanes.
Impedimetric detection of pathogenic bacteria with bacteriophages using gold nanorod deposited graphite electrodes
Authors: Moghtader Farzaneh , Congur Gulsah , Zareie Hadi M. , Erdem Arzum , Piskin Erhan
Published: September 2016

Electrochemical impedance spectroscopy (EIS) is applied for the detection of bacteria using bacteriophages as a bioprobe together with gold nanorods (GNRs).
Design and synthesis of the polymers based on alkylthiophenyl side chains and variant acceptor moieties for polymer solar cells
Authors: Liu Hailu , Zhang Zhiquan , Zeng Zhaokui , Zhao Bin , Tan Songting
Published: September 2016

Three new BDT-based polymers with alkylthiophenyl side chains and the relationship between the acceptor structure and the photovoltaic performance.
New approach of modifying the anatase to rutile transition temperature in TiO2 photocatalysts
Authors: Byrne Ciara , Fagan Rachel , Hinder Steven , McCormack Declan E. , Pillai Suresh C.
Published: September 2016

In pure synthetic titanium dioxide, the anatase to rutile phase transition usually occurs between the temperatures of 600 °C and 700 °C.
Multi-modal MR imaging and magnetic hyperthermia study of Gd doped Fe3O4 nanoparticles for integrative cancer therapy
Authors: Thorat Nanasaheb D. , Bohara Raghvendra A. , Yadav Hemraj M. , Tofail Syed A. M.
Published: September 2016

Gadolinium (Gd) doped iron oxide nano-mediator in cancer theranostics are one of the most promising candidates in combining diagnostics (imaging) and therapeutics (molecular therapy) functions in a single, multimodal platform.
Mutagenesis of precursor peptide for the generation of nosiheptide analogues
Authors: Wang Shuzhen , Zheng Xulu , Pan Qi , Chen Yijun
Published: September 2016

Thr3 in the core peptide of NosM could be mutated to generate nosiheptide analogues retaining antimicrobial activities.
Specificity of acyl-CoA binding protein to acyl-CoAs: influence on the lipid metabolism in Aspergillus oryzae
Authors: Yao Yunping , Ouyang Changsheng , Jiang Lu , Liu Xiaoguang , Hao Qing , Zhao Guozhong , Zeng Bin
Published: September 2016

Acyl-CoA binding protein (ACBP) is involved in lipid metabolism and regulation of gene expression in eukaryotic cells, however, the specific functional roles of this important class of proteins remain to be elucidated.
Low-temperature microwave-assisted hydrothermal fabrication of RGO/MnO2–CNTs nanoarchitectures and their improved performance in supercapacitors
Authors: Zhang Jie , Zhang Hailang , Cai Yingjun , Zhang Haitao
Published: September 2016

RGO/MnO2–CNTs nanoarchitectures have been successfully synthesized at low temperature and exhibit high specific capacitance and reversibility.
Spatially branched CdS–Bi2S3 heteroarchitecture: single step hydrothermal synthesis approach with enhanced field emission performance and highly responsive broadband photodetection
Authors: Bankar Prashant K. , Pawar Mahendra S. , Pawbake Amit S. , Warule Sambhaji S. , Late Dattatray J. , More Mahendra A.
Published: September 2016

This report explores the controlled hierarchical synthesis of CdS nanostructure branches on Bi2S3 nanorod cores via a facile single step hydrothermal route for field emission and photo detector applications.
Antibiotic adjuvants from Buxus sempervirens to promote effective treatment of drug-resistant Staphylococcus aureus biofilms
Authors: Abreu A. C. , Paulet D. , Coqueiro A. , Malheiro J. , Borges A. , Saavedra M. J. , Choi Y. H. , Simões M.
Published: September 2016

Plants have been long scrutinized in the quest for new antibiotics, but no strong antibiotic molecule was ever found.
A theoretical study of gas adsorption on silicene nanoribbons and its application in a highly sensitive molecule sensor
Authors: Aghaei S. M. , Monshi M. M. , Calizo I.
Published: September 2016

Silicene nanoribbon is a promising material to detect individual gas molecules with high sensitivity.
Cationic polymerization of isobutylene catalysed by AlCl3 with multiple nucleophilic reagents
Authors: Zhu Shan , Lu Yangcheng , Wang Kai , Luo Guangsheng
Published: September 2016

Adding the multiple nucleophilic reagents, iPr2O and EB, in the initiation system is an effective way to attain the controlled polymerization of isobutylene.
Floc structural characteristics of ferrum-polymer dual-coagulant for treatment of synthetic dyes wastewater: effect of solution pH, hardness and ionic strength
Authors: Li Ruihua , Gao Baoyu , Guo Kangying , Zheng Huaili , Yue Qinyan
Published: September 2016

Lignin-based flocculant (LBF) can be used as a coagulant aid to treat reactive and disperse dyes wastewater.
Low picomolar, instrument-free visual detection of mercury and silver ions using low-cost programmable nanoprobes
Authors: Rana Muhit , Balcioglu Mustafa , Robertson Neil M. , Hizir Mustafa Salih , Yumak Sumeyra , Yigit Mehmet V.
Published: September 2016

A single gold nanoprobe can be programmed for low picomolar visual detection of inorganic mercury and/or silver in water, soil or urine samples.
Zn electrode with a layer of nanoparticles for selective electroreduction of CO2 to formate in aqueous solutions
Authors: Zhang Taotao , Zhong Hexiang , Qiu Yanling , Li Xianfeng , Zhang Huamin
Published: September 2016

A Zn electrode with a layer of nanoparticles exhibits high selectivity and activity for electrochemical CO2 reduction to formate.
Achieving 10.5% efficiency for inverted polymer solar cells by modifying the ZnO cathode interlayer with phenols
Authors: Fu Ping , Guo Xin , Zhang Bin , Chen Tao , Qin Wei , Ye Yun , Hou Jianhui , Zhang Jian , Li Can
Published: September 2016

A simple treatment of the ZnO cathode interlayer with phenols (both on the ZnO surface and in blend) for IPSCs.
Human serum albumin encapsulated gold nanoclusters: effects of cluster synthesis on natural protein characteristics
Authors: Russell B. A. , Jachimska B. , Kralka I. , Mulheran P. A. , Chen Y.
Published: September 2016

The differences in the physiochemical properties between native Human Serum Albumin (HSA) and HSA encapsulated gold nanoclusters (HSA-AuNCs) are characterised.
The design of a multifunctional dendrimer-based nanoplatform for targeted dual mode SPECT/MR imaging of tumors
Authors: Luo Yu , Zhao Lingzhou , Li Xin , Yang Jia , Guo Lilei , Zhang Guixiang , Shen Mingwu , Zhao Jinhua , Shi Xiangyang
Published: September 2016

A multifunctional dendrimer-based nanoplatform labeled with 99mTc can be synthesized for targeted SPECT/MR dual mode imaging of tumors.
Environment-friendly carbon nanotube based flexible electronics for noninvasive and wearable healthcare
Authors: Dinh Toan , Phan Hoang-Phuong , Nguyen Tuan-Khoa , Qamar Afzaal , Foisal Abu Riduan Md , Nguyen Viet Thanh , Tran Canh-Dung , Zhu Yong , Nguyen Nam-Trung , Dao Dzung Viet
Published: September 2016

Carbon nanotube yarns are employed to develop environment-friendly, low cost and lightweight paper-based flexible devices for wearable applications in temperature and respiratory monitoring, and personal healthcare.
Regulation of divalent metal transporter-1 by serine phosphorylation
Authors: Seo Young Ah , Kumara Ruvin , Wetli Herbert , Wessling-Resnick Marianne
Published: September 2016

Divalent metal transporter-1 (DMT1) mediates dietary iron uptake across the intestinal mucosa and facilitates peripheral delivery of iron released by transferrin in the endosome. Here, we report that classical cannabinoids (Δ9-tetrahydrocannabinol, Δ9-THC), nonclassical cannabinoids (CP 55,940), aminoalkylindoles (WIN 55,212-2) and endocannabinoids (anandamide) reduce 55Fe and 54Mn uptake by HEK293T(DMT1) cells stably expressing the transporter. siRNA knockdown of cannabinoid receptor type 2 (CB2) abrogated inhibition. CB2 is a G-protein (GTP-binding protein)-coupled receptor that negatively regulates signal transduction cascades involving serine/threonine kinases. Immunoprecipitation experiments showed that DMT1 is serine-phosphorylated under basal conditions, but that treatment with Δ9-THC reduced phosphorylation. Site-directed mutation of predicted DMT1 phosphosites further showed that substitution of serine with alanine at N-terminal position 43 (S43A) abolished basal phosphorylation. Concordantly, both the rate and extent of 55Fe uptake in cells expressing DMT1(S43A) was reduced compared with those expressing wild-type DMT1. Among kinase inhibitors that affected DMT1-mediated iron uptake, staurosporine also reduced DMT1 phosphorylation confirming a role for serine phosphorylation in iron transport regulation. These combined data indicate that phosphorylation at serine 43 of DMT1 promotes transport activity, whereas dephosphorylation is associated with loss of iron uptake. Since anti-inflammatory actions mediated through CB2 would be associated with reduced DMT1 phosphorylation, we postulate that this pathway provides a means to reduce oxidative stress by limiting iron uptake.
Area and energy‐efficient physically unclonable function based on k‐winners‐take‐all
Authors: Dhar T. , Trivedi A.R.
Published: September 2016

An area and energy‐efficient physically unclonable function (PUF) based on k‐winners‐take‐all (k‐WTA) is presented. Competitive computing dynamics of k‐WTA reduces key‐generation cell in WTA‐based PUF to a single transistor, necessary for area/energy‐constrained applications. Differential key generation in the PUF generates stable keys at varying temperature and supply voltage variations. Array design considerations for WTA‐PUF are studied. Performance of k‐WTA‐based PUF is compared against the static random access memory (SRAM)‐based PUF.
QBPS in RF front‐ends
Authors: Dempster A.G. , Cetin E.
Published: September 2016

Quadrature bandpass sampling (QBPS) offers a reduced complexity alternative to sampled quadrature (Q) downconversion. However, if the in‐phase and quadrature sequences produced are reconstructed at the baseband in the same manner, distortion will result. The effects of this distortion are examined with a view to establish the best way to process the QBPS sequences.
Reference Disposition Modulation Method for non‐ideal Dual Z‐Source Neutral‐Point‐Clamped Inverter
Authors: Roomi Muhammad M. , Maswood Ali I. , Dehghani Tafti Hossein , Harikrishna Raj Pinkymol
Published: September 2016

A single stage Z‐source Neutral‐Point‐Clamped (NPC) inverter for buck‐boost conversion is considered as a better alternative for the two‐staged energy conversion in traditional inverters. The Dual Z‐Source Network (DZSN) uses two distinct X‐shaped impedance networks to connect two individual dc sources to the inverter circuit. The output voltage boosting can be achieved by selectively shooting‐through the power sources in the dual networks. This study proposes a novel modulation method for integrating the shoot‐through state to the traditional inverter switching. The performance of the proposed modulation method for DZSN is examined utilising attributes which include, voltage boosting, switching losses, efficiency, etc. In addition, this study also deals with non‐ideal DZSN, where the circuit resistance and their respective voltage drops are considered. The presented modulation method uses a single carrier signal which is compared with two sets of sinusoidal reference signals to establish the switching. The theoretical findings of the proposed modulation method are verified using Matlab/Simulink and PSIM software. Moreover, an experimental NPC prototype was built and the results for the different values of modulation index are presented, which validate the applicability of proposed modulation method.
Flexibility evaluation of integrating solar power into the Nigerian electricity grid
Authors: Eni Richardson O. , Akinbami John‐Felix K.
Published: September 2016

The study evaluated the capability of current thermal generation to back‐up variation generation from solar energy penetration into the Nigerian power grid from a system operation perspective using security constraint unit commitment model. This provides an empirical evidence of the impacts that can tip the balance towards a sustainable future low carbon electricity mix. Through 10 and 20% solar energy penetration scenarios, greenhouse reduction of 1975.70 and 3590.03 lb/day, respectively, can be achieved. However, daily peak‐valley net demand difference to be supplied by the thermal plants will increase from 702.5 to 857.5 and 1607.5 MW, numbers of daily start‐up will increase from 23 to 30 and 25, daily system spinning reserve will increase from 723 to 757 and 815 MW and daily idle hours of the thermal plants will increase from 52 to 71 and 72 h, in a 10 and 20% solar energy integrated system, respectively. The daily operational revenue of the thermal plants will also reduce by 5.5 and 7.9% in a 10 and 20% solar energy integrated system, respectively. These are useful data in developing policy framework for the future electricity market as the country diversify her energy source and mitigate greenhouse effect.
An Overview of Maxillofacial Trauma in Oral and Maxillofacial Tertiary Trauma Centre, Queen Elizabeth Hospital, Kota Kinabalu, Sabah
Authors: Lee CheeWei , Foo QiChao , Wong LingVuan , Leung YiuYan
Published: September 2016

The aims of this study were to provide an overview of maxillofacial trauma and its relationship to patient's demographic data and alcohol consumption within the state of Sabah. It was a retrospective study of maxillofacial trauma cases treated by Oral and Maxillofacial Surgery Department, Queen Elizabeth Hospital, Kota Kinabalu, Sabah, from January 1, 2009, until December 31, 2013. A total of 630 maxillofacial trauma cases were included. Details of the trauma were collected from patients’ record, including patients’ cause of injuries, injuries suffered, treatment indications, and treatment received. Patients’ demographic data (age, gender), alcohol consumption in relation to causes, and type of maxillofacial injury were analyzed. There were 538 male (85.4%) and 92 female (14.6%) patients (ratio: 5.8:1), with mean age of 31.0 years. Most common causes of maxillofacial injury were motor vehicle accident (MVA; 66.3%), followed by fall (12.4%) and assault (11.6%). Motorcyclists made up more than half of the total cases (53.1%). Cases referred were primarily due to soft-tissue injury (458 cases). Other cases were dentoalveolar and maxillofacial bone fractures. Treatment provided for the fractures included open reduction and internal fixation (22.9%), closed reduction (28.7%), and conservative management (48.4%). Toilet and suturing were done for all patients with soft-tissue injury. Maxillofacial trauma is a major problem in Sabah. It affects mostly males in the age group of 21 to 30 years. Most of the MVA patients were motorcyclists. Mandibular fracture with parasymphysis involvement recorded the highest number. Most of the patients preferred conservative management, probably due to financial and logistic issue.
The “Hoop” Plate for Posterior Bicondylar Shear Tibial Plateau Fractures: Description of a New Surgical Technique
Authors: Schatzker Joseph , Kfuri Mauricio , Giordano Vincenzo
Published: September 2016

High-energy fractures of the proximal tibia with extensive fragmentation of the posterior rim of the tibial plateau are challenging. This technique aims to describe a method on how to embrace the posterior rim of the tibial plateau by placing a horizontal precontoured one-third tubular plate wrapped around its corners. This method, which we named “hoop plating,” is mainly indicated for cases of crushed juxta-articular rim fractures, aiming to restore cortical containment of the tibial plateau. Through a lateral approach with a fibular head osteotomy (Lobenhoffer approach), both anterolateral and posterolateral fragments are directly reduced and supported by a one-third tubular plate of adequate length. The plate is inserted from lateral to medial deep to all soft tissues, and its position is checked with fluoroscopy. The implant sits exactly on the posterior cortex of the tibial plateau and provides containment for the reduced juxta-articular posterior cortex and rim. We begin with immediate range of motion. Toe-touch weight-bearing with crutches is allowed with the operated knee in full extension. Weight-bearing is gradually increased only after 6 weeks as bone healing is taking place. Clinical follow-up is performed at 1, 3, 6, and 12 weeks. If the radiological exam confirms that the fracture is healed, the patient is allowed to proceed to muscle strengthening and bear weight entirely. The “hoop plating” may be a good option for the management in cases of extensive posterior tibial plateau articular surface fracture and impaction with rim and posterior cortical wall fragmentation.
Single-photon emission at 1.5 μm from an InAs/InP quantum dot with highly suppressed multi-photon emission probabilities
Authors: Miyazawa T. , Takemoto K. , Nambu Y. , Miki S. , Yamashita T. , Terai H. , Fujiwara M. , Sasaki M. , Sakuma Y. , Takatsu M. , Yamamoto T. , Arakawa Y.
Published: September 2016

We have demonstrated highly pure single-photon emissions from an InAs/InP quantum dot at the wavelength of 1.5 μm. By applying quasi-resonant excitation, one exciton is deterministically generated in an excited state, which then relaxes to the exciton ground state before recombining to emit a single photon. The photon-correlation function of the emission from the exciton ground state exhibits a record g(2)(0) value of (4.4 ± 0.2) × 10−4 measured using high-performance super-conducting single-photon detectors, without any background subtraction. This single-photon source with extremely low multi-photon emission probability paves the way to realize long distance quantum key distribution and low error-rate quantum computation.
Local complete active space second-order perturbation theory using pair natural orbitals (PNO-CASPT2)
Authors: Menezes Filipe , Kats Daniel , Werner Hans-Joachim
Published: September 2016

We present a CASPT2 method which exploits local approximations to achieve linear scaling of the computational effort with the molecular size, provided the active space is small and local. The inactive orbitals are localized, and the virtual space for each electron pair is spanned by a domain of pair-natural orbitals (PNOs). The configuration space is internally contracted, and the PNOs are defined for uniquely defined orthogonal pairs. Distant pair energies are obtained by multipole approximations, so that the number of configurations that are explicitly treated in the CASPT2 scales linearly with molecular size (assuming a constant active space). The PNOs are generated using approximate amplitudes obtained in a pair-specific semi-canonical basis of projected atomic orbitals (PAOs). The evaluation and transformation of the two-electron integrals use the same parallel local density fitting techniques as recently described for linear-scaling PNO-LMP2 (local second-order Møller-Plesset perturbation theory). The implementation of the amplitude equations, which are solved iteratively, employs the local integrated tensor framework. The efficiency and accuracy of the method are tested for excitation energies and correlation energies. It is demonstrated that the errors introduced by the local approximations are very small. They can be well controlled by few parameters for the distant pair approximation, initial PAO domains, and the PNO domains.