bluuebunny/crossref_metadata_2025 huggingface dataset:
Uji Aktivitas Antibakteri Ekstrak Terpurifikasi Daun Mangga Arumanis (Mangifera indica L.) dan Identifikasi Flavonoid dengan KLT
Authors: Kunti Mulangsri Dewi Andini , Zulfa Elya
Published: March 2020

Arumanis mango leaves (Mangifera indica L.) has antibacterial activity and antifungal, evidently. Escherichia coli and staphylococcus aureus are opprtunistic pathogen bacteria that can cause gastrointestinal and skin infection. Purification of extract was done to eliminate the presence of ballast substances that cannot produce therapeutic effects. This study aims to acknowledge the antibacterial activity of purified mango arumanis leaves extract (PMALE) against E. coli and S. aureus, flavonoid compound content by TLC. Arumanis Mango leaves powder was extracted with 96% ethanol solvent by maceration method, followed purification the extract was done with hot water-ethylacetate solvent by liquid-liquid extraction method. Antibacterial activity test was done by agar diffusion method against E. coli and S. aureus bacteria with the same serial concentration of 6.25; 12.5; 25; 50; 75 and 100% and Thin Layer Chromatography (TLC) tests for detection flavonoid compounds, the stationary phase used silica gel 60F 254 and the mobile phase used n-hexane-ethylacetate (1:3). The results of PMALE had antibacterial activity at lower concentrations 6,25% against both of E. coli and S. aureus. PMALE had flavonoid compounds with Rf values of 0.81.
Uji Efektivitas Anthelmintik Formula Suspensi Biji Mentimun (Cucumissativus L.) Terhadap Cacing Gelang (Ascaris Lumbricoides)
Authors: Farid Nurfiddin , Syamsu Andi Suparlan Isya , Aliah Ahmad Irsyad , Murdi Anna Muthmainna
Published: March 2020

The Effectiveness Test of Cucumber Seeds Suspension Formula (Cucumis sativus L) towards Roundworms (Ascaris lumbricoides) as in Vitro Anthelmintic, It has been conducted research to know cucumber seeds powder (Cucumis sativus L) can be made into form of suspension stock and to know stock of cucumber seeds suspension (Cucumis sativus L) can give effect of anthelmintic toward roundwoms Ascaris lumbricoides. The research was conducted by using experimental method. Powder of cucumber seeds (Cucumis sativus L) were made into suspension stock with 3 concentratios such as 5%, 10%, 15% concetrations and suspension without powder of cucumber seeds (Cucumis sativus L) with different addition subtance concentration. Test animal used was roundworm (Ascaris lumbricoides) that was taken by pig’s intestine. Treatment group consisted into five categories such as 125 mg positive control of pamoat pirantel (Combantrin®), negative control of suspension without powder of cucumber seeds (Cucumis sativus L), and category of cucumber seeds suspension (Cucumis sativus.L) as 5%, 10%, and 15%. Each group was soaked with 40 ml test ingredient into petri dish. Then it was observed and writte the number of died worms in every minute. 100% observation of died worm was group of positive control at 405 minutes, negative control at 1710 minutes, 5% concetration of cucumber seeds suspension stock at 540 minutes, 10%concentration at 465 minutes and 15% concentration at 420 minutes. The result of research showed that cucumber seeds (Cucumis sativus L) can be made into suspension stock and effective as anhelmintic toward roundworms Ascaris lumbricoides.
Aktivitas Ekstrak Daun Salam (Syzygium polyanthum) sebagai Antirheumatoid Artritis pada Tikus yang Diinduksi Complete Freund’s Adjuvants (CFA)
Authors: Amirah Sitti , Wati Aulia , Putra Bayu , Alani Fitri Wasto
Published: March 2020

Rheumatoid arthritis is an chronic autoimmune disease, which is characterized by inflammation and degradation of the joints and cartilages. Rheumatoid therapy is currently using immunosuppressant drugs, nonsteroidal anti-inflammatory drugs and corticosteroids. Treatment of chronic rheumatoid can trigger side effects. Syzygium polyanthum leaves contain alkaloid compounds, flavonoids, saponins, tannins and essential oils consist of citral and eugenol which are thought to be potential as antirheumatoid. This study aims to determine the effect antirheumatoid arthritis and effective dose of ethanol extracts of  Syzygium polyanthum  leaf. This study used 15 male rats. Treatment started by measuring foot volume using a pletismometer and then inducting CFA intraplantary as much as 0,1 mL on day 1 and left until day 16th. On the day 17th a foot volume and arthritis index was measured and then treated until the day 30th. The animals were divided into 5 groups: negative control (Na. CMC 1%), positive control (methylprednisolone dose 1.646 mg / kg BW), ethanol extractof Syzygium polyanthum  leaf at a dose of 75 mg / kg, 150 mg / kg and 300 mg / kg. On the day 31st, foot volume and arthritis index measurements were taken again. The results showed a decrease in foot volume and arthritis index after given of the extract. Foot volume difference data were analyzed using the One Way Anova test followed by the Post Hoc LSD test. The difference between the arthritis index data was analyzed using Kruskal-Wallis followed by the Mann-Whitney test. Statistical results show that positive control has the same effect as extract (P> 0.05). Based on the results of statistical analysis of inflammation of the foot volume and the arthritis index shows that the ethanol extract of Syzygium polyanthum  leaf had an effect as an antirheumatoid arthritis
Perbaikan Kelarutan Albendazol Melalui Pembentukan Kristal Multikomponen dengan Asam Malat
Authors: Alatas Fikri , Abdul Azizsidiq Fahmi , Hartyana Sutarna Titta , Ratih Hestyari , Nurono Soewandhi Sundani
Published: March 2020

An effort to improve the solubility of albendazole (ABZ), an anthelmintic drug has been successfully carried out through the formation of multicomponent crystal with dl-malic acid (MAL). Construction of phase solubility curve of ABZ in MAL solution and crystal morphological observations after recrystallization in the acetone-ethanol (9:1) mixture were performed for initial prediction of multicomponent crystal formation. ABZ-MAL multicomponent crystal was prepared by wet grinding or also known as solvent-drop grinding (SDG) with acetone-ethanol (9:1) mixture as a solvent followed by characterization of the multicomponent crystal formation by powder X-ray diffraction and Fourier transform infrared (FTIR) methods. The solubility of ABZ-MAL multicomponent crystal was tested in water at ambient temperature and in pH 1.2, 4.5 and 6.8 of buffered solutions at 37°C. The phase solubility curve of the ABZ in the MAL solution showed type Bs. The ABZ-MAL mixture has a different crystalline morphology than pure ABZ and MAL after recrystallization in the acetone-ethanol mixture (9:1). The powder X-ray diffraction pattern and the FTIR spectrum of ABZ-MAL from SDG different from intact ABZ and MAL powder X-ray diffraction patterns and these results can indicate the ABZ-MAL multicomponent crystal formation. The ABZ-MAL multicomponent crystal has better solubility than pure ABZ in all media used. These results can be concluded that ABZ-MAL multicomponent crystal can be prepared by solvent-drop grinding method with acetone-ethanol (9:1) mixture as a solvent and can increase the solubility of albendazole.
Aktivitas Antioksidan dan Penghambatan Xantin Oksidase Kulit Batang Songi (Dillenia serrata Thunb.)
Authors: Sabandar Carla Wulandari , Jalil Juriyati , Ahmat Norizan , Aladdin Nor-Ashila , Kamaruddin Harni Sartika , Wahyuningrum Retno
Published: March 2020

Songi (Dillenia serrata) is a tree endemic to Southeast Sulawesi and its stem bark been used in folk medicine. Nonetheless, only a handful scientific knowledge regarding chemistry and biological activities has been investigated on the plant. The present study aimed to investigate the antioxidant and xanthine oxidase (XO) inhibitory activity of the stem bark of the plant. Methanol extract and organic fractions (petroleum ether, ethyl acetate, and methanol) of the dried powdered stem bark of songi were evaluated for phytochemical screening, total phenolic (TPC), total flavonoid contents (TFC), DPPH, FRAP, and XO in vitro assays. Flavonoids, tannins, terpenoids, steroids, and saponins present in the extract. TPC and TFC in extract were 59.2 mg GAE/g and 23.4 mg QE/g. The contents in organic fractions were in solvent-dependent manner (methanol>ethyl acetate>petroleum ether). Extract and fractions scavenged DPPH radicals (48.2–59.7%) at 100 μg/mL compared to ascorbic acid, trolox, and gallic acid (90.3–93.8%). FRAP values varied from 0.8–3.4 μg/μg equivalent trolox amount (quercetin and gallic acid were 25.7 dan 32.4 μg/μg, respectively). They also inhibited xanthine oxidase (15.3–50.3%) at 100 μg/mL (allopurinol, 98.2%). The study concluded the potential of methanol extract and organic fraction of the stem bark of songi, thus highlighted the prospect of songi to be used in herbal and drugs development from nature.
Uji Aktivitas Antioksidan Ekstrak Daun Karet Kebo (Ficus Elastica) dengan Metode Peredaman Radikal Bebas Dpph (1,1-Diphenyl-2-Picrylhydrazil)
Authors: Handayani Selpida , Kurniawati Ida , Abdul Rasyid Faradiba
Published: March 2020

Ficus elastica leaf is one of the Ficus species assumed to be rich in polyphenols so that it can act as an antioxidant. The research aimed to determine the antioxidant activity and IC50 value of methanol and water extracts of rubber leaf. In this research, the extraction was conducted by maceration using methanol and obtained the yield value of 7,03%, while the infundation using water obtained the yield value of 2,82%. The antioxidant activity test was conducted by DPPH free radical scavenging (1,1-diphenyl-2-phycrilhydrazyl) using a quercetin comparator. The qualitative tests were conducted by TLC method using dicloromethane:methanol eluent with a ratio of 99:1 for methanol extracts, and a ratio of 95:5 for water extracts, where all extracts of both methanol and water positively container antioxidants characterized by the formation of yellow spots with a purple background on TLC plates. The results of the quantitative test shower that the methanol extract had medium antioxidant activity with an IC50 value of 78,39 µg/mL, and water extract had an inactive antioxidant activity with an IC50 value of 319,11 µg/mL. While quercetin was classified as a very strong antioxidant with an IC50 value of 7,62 µg/mL.
Desain Turunan Senyawa Leonurine Sebagai Kandidat Obat Anti Inflamasi
Authors: Beny Ruslin , Yana Nindy Rachma Az , Leorita Mesi
Published: March 2020

In this research, there was docking process of leonurine compounds and their derivatives to Cyclooxygenase-2 (COX-2) enzyme as an anti-inflammatory. The receptor code used is 6COX which is downloaded from the protein data bank site (PDB). The aims of this study was to investigate the interaction of leonurine compounds and their derivatives against COX-2 receptors. All compounds are docked using AutoDock 4.2 software. The docking validation is performed by tethering the ligand-receptor with the parameter of the Root Mean Square Deviation (RMSD) value <2 Å. From the docking validation results, have been obtained RMSD value = 0.31 Å. Analysis of docking results indicates that leonurine and its derivatives are predicted to have good interaction with COX-2 receptors. From the results of this research, it can be concluded that leonurine compounds and their derivatives have inhibitory activity against COX-2 receptors. The docking results showed the lowest binding energy value ligand-receptor (ΔG) best matched in the 11th derived compound which is -7.95 kcal/mol.
Diarrea crónica como manifestación de un tumor neuroendocrino
Authors: Sandoval Alzate Hector Fabio , Gonzalez Clavijo Angelica Maria , Angarita Claro Maria Camila , Rosado Rodriguez Micela Beatriz , Arenas Diaz Ruben Dario
Published: April 2020

Las neoplasias neuroendocrinas (Neuroendocrine Neoplasms, NEN) constituyen un grupo heterogéneo de neoplasias poco frecuentes, que se originan en las células endocrinas, con la capacidad de secretar aminas y polipéptidos hormonales. Las NEN de localización pancreática (pNEN) pueden ser funcionales o no funcionales. Las pNEN funcionales secretan hormonas como la gastrina, la insulina y el glucagón y otras menos frecuentes como el péptido intestinal vasoactivo (PIV), por lo que sus características sindromáticas dependen del péptido secretado. Los vipomas se manifiestan con diarrea crónica de características secretoras, que usualmente conducen a trastornos hidroelectrolíticos e incluso a complicaciones serias asociadas como la falla renal. A continuación, se describe el caso de un hombre de 37 años con diarrea crónica de 6 meses de evolución y frecuentes hospitalizaciones por trastornos hidroelectrolíticos, generados por hipocalemia severa y lesión renal aguda por deshidratación. Después de múltiples estudios, se considera el diagnóstico de una diarrea secretora por NEN funcional, secretora de PIV. Por tanto, se inicia una terapia empírica con octreotida y se logra controlar la diarrea, así como corregir el trastorno hidroelectrolítico. Además, se amplían los estudios, para documentar las pNEN tratadas mediante intervención quirúrgica, con respuesta clínica favorable y remisión completa de la sintomatología.
Várices esofágicas superiores (Downhill varices). Presentación de casos y revisión de la literatura
Authors: Ángel Arango Luis Alberto , Donado Moré Andrés Felipe
Published: April 2020

Se describen 21 casos con hallazgo incidental de várices esofágicas superiores (Downhill varices) en endoscopia de las vías digestivas altas. Además, se detallan algunos datos relevantes de la historia clínica y de los hallazgos endoscópicos. La relación hombres/mujeres fue 1:1 y la edad promedio fue de 67,9 años. La comorbilidad más frecuente fue la enfermedad pulmonar obstructiva crónica (EPOC), seguida de las neumoconiosis, la obesidad y el síndrome de apnea-hipopnea, todas con hipertensión pulmonar (HTP) asociada. Las tres últimas causas no han sido descritas previamente en la literatura sobre várices esofágicas superiores. Ningún paciente tenía antecedente de hemorragia variceal.
The informative and the performative in semi-structured interviews: The example of a study of territorial capital in Serbia
Authors: Spasic Ivana
Published: April 2020

The paper reexamines the semi-structured interview method on the basis of
data collected in a study of medium-sized Serbian towns. The analysis of
transcripts shows that the analytic quality of data varied depending on the
interviewee?s position in the local institutional structure, so that in
interviews with representatives of political and social institutions role
playing (the performative) prevailed over providing information on social
reality and attitudes (the informative). This finding is situated in the
context of current debates within qualitative methodology which, while
illuminating the complex intertwining of different dimensions of the
interview (as source of data and interaction situation), fail to recognize
fully the problem of performativity and provide solutions. In the final
section some undesired epistemological and political implications are
discussed of an uncritical application of the semi-structured interview if
conceived in an overly antipositivistic fashion and disregarding the
institutional and broader social framework within which the research takes
place.
Corrigendum: Design and analysis of double-pipe heat exchanger with new arrangements of corrugated tubes using honeycomb arrangements, published in the journal Thermal Science, Year 2020, No. 1A, Vol. 24, pp. 635-643
Authors: Editorial E
Published: April 2020

Corrigendum by Simeon
Oka, Editor-in-Chief of the journal Thermal Science request that it is
necessary write exact personal name of 2nd author of the paper DESIGN AND
ANALYSIS OF DOUBLE-PIPE HEAT EXCHANGER WITH NEW ARRANGEMENTS OF CORRUGATED
TUBES USING HONEYCOMB ARRANGEMENTS by Risuwana Begam HAJ MAIDEEN a* and
Sivashankar SOMU b a Department of Mechanical Engineering, Sir Issac Newton
College of Engineering and Technology, Nagapattinam, Tamilnadu, India b
Department of Mechanical Engineering, Government College of Engineering,
Sengipatti, Tanjore, Tamilnadu, India Original scientific paper
https://doi.org/10.2298/TSCI190602458H published in the journal Thermal
Science, Year 2020, No. 1A, Vol. 24, pp. 635-643 since due to typing error
of the Corresponding author, personal name of the 2nd author was written as
Sivashankar instead of correctly Sivasankar.

 Link to the corrected article 10.2298/TSCI190602458H
Precise laser trimming of alloy strip resistor: A comparative study with femtosecond laser and nanosecond laser
Authors: Su Qiuyue , Bai Shi , Han Jitai , Ma Ying , Yu Yongchao , Deng Yangbao , Wu Meiping , Zheng Chong , Hu Anming
Published: April 2020

Laser trimming has become one of the powerful tools for precise manufacturing of alloy resistors that are widely used in electrical vehicles, electrical controlling, and in appliances. In this work, the influence of femtosecond laser trimming is compared with nanosecond laser trimming. The authors found that lasers focused on different heights relative to the sample surface induced significant changes in surface morphologies. The resistance change was systematically investigated as a function of cutting lengths and cutting depths of different laser powers for both lasers. The experiments display that femtosecond laser trimming has a higher precision of the resistance adjustment than nanosecond laser trimming. The periodic ripple structure by the femtosecond laser was investigated at the focus position above, onto, or beneath the surface. The period of a low frequency ripple structure (LFRS) on the ablated groove bottom is about 600–700 nm when the laser focuses just right on the surface but changes to 490–560 nm when focusing above or beneath the surface. The period of a high frequency ripple structure is about 100–380 nm at the vertical direction of LFRS. The period of low frequency ripple on the outside of the groove is smaller than that on the groove bottom for all three focusing cases. The period of the LFRS is not sensitive to the laser power. The range of the resistor value change in the s-polarized light direction of the femtosecond laser is more than that in the p-polarized light direction.
An Introduction to Sustainable Tourism
Authors: Coghlan Alexandra
Published: March 2020

A comprehensive, pragmatic, and realistic look at integrating sustainability into tourism. It adopts a systems-perspective, looking at the whole tourism supply chain to provide an integrated viewpoint of sustainability in the tourism industry.
Sustainable Tourism Policy Frameworks
Authors: Coghlan Alexandra
Published: March 2020

Having looked at the external and internal challenges facing the move towards more sustainable tourism, and the impacts of tourism, you should now be wondering how sustainability in tourism can be turned into more than an ideal. Perhaps one of the most obvious way to achieve this is simply to regulate the sector. After all regulation worked for the ozone layer: scientists raised the alarm in the 1970s that a hole was appearing in the atmosphere’s ozone layer, caused by Ozone Depleting Substances or ODS (most notably CFCs) and resulting in adverse effects on human health and the environment. By 1987 the Montreal Protocol was established to phase out the use of ODS, and by June 2015, all countries in the United Nations, the Cook Islands, Holy See, Niue and the supranational European Union had ratified the original Protocol. The result was a 98% drop in ODS since ratification, and the hole is expected to have fully repaired itself by 2050. A significant achievement in terms of international cooperation, based on scientific advice.
Ethics and Values
Authors: Coghlan Alexandra
Published: March 2020

Ethical concerns underpin the sector of sustainable tourism. Ethics is what allows us to make decisions about daily interactions with others and the world around us – it is fundamental to constructing the types of sustainable relationships that we have already discussed in Chapter 1. At its most basic level ethics distinguishes right from wrong. Its place in sustainable tourism is so important that an ethics-based platform has been suggested as an extension of the advocacy à cautionary à adaptancy à knowledge-based platforms that we reviewed in Chapter 1. Macbeth (2005) calls for a sixth platform in tourism studies, an ethics platform – he places this even after a fifth sustainability platform. An ethics platform provides us with the moral compass to make decisions about all our travel-related decisions, especially the hard ones that we don’t like to think about.
Operationalising Sustainable Tourism
Authors: Coghlan Alexandra
Published: March 2020

As well as simply (!) learning to keep the three sustainability balls in the air, it’s important to know how to juggle these balls in a coherent and pleasing manner – after all tourism is part of the experience economy and we want to deliver something that is engaging and attractive to its end users, tourists. This chapter therefore discusses how to operationalise sustainability in tourism. Some have tried to do this at the level of a destination, creating the ‘Green Destinations’ brand (Figure 8.1). It’s a laudable effort and one which hopefully will lead to greater sustainability for the sector as a whole in the long run. Given what we know about the complexity of the tourism system, creating a green destination is, however, perhaps outside the scope of this book, and of most of us as practitioners or tourism business managers.
Change and Innovation
Authors: Coghlan Alexandra
Published: March 2020

By its very definition sustainable tourism is a both a current- and a future-oriented activity; it’s tourism “that takes full account of its current and future economic, social and environmental impacts, addressing the needs of visitors, the industry, the environment and host communities” according to the UNWTO. Understanding sustainable tourism and managing therefore has a very strong future-oriented component, which is the focus of this chapter. Often, when we want to understand the future, one of the first things that we need to do is look to the past to identify the trends that have got us to where we are now, and that, in all likelihood, will continue to be trends into the future. The context for tourism’s future is a history of spectacular and sustained growth, measured in terms of volume, geographic spread, economic benefits, as well as environmental and social impacts. Going back 40 years to the 1970s, tourism has grown from under 70 million international tourist arrivals, to over 1 billion international tourist arrivals in 2012, according to UNWTO estimates.
Challenges to Implementing Sustainability Practices in Tourism
Authors: Coghlan Alexandra
Published: March 2020

So has sustainability in tourism actually reached a point of stagnation? The answer on the surface may well be ‘yes’ . At first glance, it would appear that tourism has moved little beyond flight carbon offset schemes, high efficiency lightbulbs, and towel re-use schemes. The cynics would also point to ‘greenwashing’ within tourism, talking up environmental benefits to give the appearance of greater sustainability than is actually occurring. Why would this be? The inclusion of sustainability-related behaviours within a business (green-washing or otherwise) tends to happen for one or several of three reasons. (1) To ward off the imposition of tighter government regulation on tourism activities (2) To tap into this apparently growing market of green consumers, who seek out environmentally and socially sustainable products and services (3) To enhance the social licence of businesses operating in sensitive areas (cruise ships travelling to the highly sensitive Antarctic environment, for example).
Governance and Partnerships
Authors: Coghlan Alexandra
Published: March 2020

The previous chapter addressed frameworks and regulations that support the move towards sustainable tourism. On their own however, these are not enough. First, they need ‘buy-in’ from the people who will be affected by them, the stakeholders on the ground. Second, they may not always be fully supported by politicians and governors, who can overturn policies at different opportunities. We don’t need to think any further than US President Trump making a shock statement on June 1 2017 that his country would withdraw from the Paris Agreement, jeopardising the whole process, as the US is one of the largest producers of GHG emissions.
Introduction
Authors: Coghlan Alexandra
Published: March 2020

Sustainability is often represented as resting on the three founding pillars of social, environmental and economic sustainability (people, planet and profit) – a firm, immovable foundation, upon which all else rests. Build these correctly at the start and the rest will follow, freeing you up to focus on the day to day running of operations.
Perfil TIC de estudiantes de la licenciatura en Educación de la UNACAR
Authors: Diez Irizar Gisela Aquilea , Herrera Sánchez Beatriz , Flores Hernández Jesús Alejandro
Published: March 2020

El objetivo central de este texto es dar a conocer el perfil que tienen los estudiantes de primer semestre de la licenciatura en Educación de la Universidad Autónoma del Carmen (Unacar) en cuanto a habilidades, conocimientos y condiciones materiales individuales y colectivas para el empleo de las tecnologías de la información y la comunicación (TIC). Para ello, se realizó una investigación de tipo cuantitativa, con un alcance descriptivo. El instrumento, una encuesta con 20 reactivos de opción múltiple, estuvo basado en el Cuestionario sobre usos de las TIC entre estudiantes universitarios barineses (Universitat Oberta de Catalunya, 2006), el cual fue adaptado a las características de la población objeto de estudio, las condiciones particulares de las universidades en México, así como la zona en la que se realiza este estudio. Se seleccionó una muestra no aleatoria de 52 estudiantes de los dos grupos primer ingreso, en el ciclo escolar de febrero a julio del 2019,  de la licenciatura en Educación de la Unacar, ubicada en el estado de Campeche. Los resultados obtenidos indican que, del total de la muestra, 44 % permanece conectado a Internet de 13 a 20 horas semanales. Asimismo, 50 % de los encuestados no posee equipo de cómputo personal en sus casas, por lo que realizan sus tareas en algún ciber (33%) o en la universidad (25%). A pesar de que 44 % comenzó a utilizar la computadora entre los 3 y 10 años de edad, solo 19 % la utiliza para actividades académicas; 75 % emplea el Internet para comunicarse con sus compañeros de clase por correo electrónico, fundamentalmente. Aunado a ello, 46 % no ha participado en foros en línea ni tiene experiencia en varios programas informáticos; 49 % emplea el Internet solo para buscar información para las clases. A pesar de todo, 92 % de los estudiantes consideran muy importante el empleo de las TIC en su futura profesión.
¿Enfrentar el COVID 19 o aprender de su embate?
Authors: Herrera Diego
Published: March 2020

La pandemia del coronavirus SARS-Cov-2 viene marcada por su letalidad, su transmisibilidad y su impacto sanitario. Aunque su capacidad letal no es extremadamente alta (alrededor del 3 por ciento), es mucho mayor que la de la gripe (0,1 por ciento) y es más grave en los grupos de edad avanzada, personas con patologías previas y en las clases sociales, mujeres y grupos más frágiles.Presentamos aquí una actualización del editorial publicado en marzo 6 de este año, a propósito de la nueva evidencia encontrada y los planteamientos clásicos de la APS
Melanoma maligno: frecuencia y distribución en un hospital de referencia de la seguridad social
Authors: Ureña-Lopez Valeria , Flores-Mendez1 Katty , Lafuente-Cevallos Lizeth , Flores-Figueroa Carolina , Erazo-Beltran Giselle , Freire-Murgueytio Patricio
Published: March 2020

Objetivo: Describir la frecuencia, magnitud y tratamiento de los diversos tipos de melanoma diagnosticados en el Hospital de Especialidades Carlos Andrade Marín (HECAM) de la ciudad de Quito.Métodos: Se realizó un estudio transversal de los pacientes que acudieron a la clínica de Melanoma del servicio de Dermatología del HECAM, durante los años 2013 a 2018. Se tomó en cuenta a todos los pacientes con histopatología diagnóstica de cualquier tipo de melanoma maligno y que tuvieron tratamiento y seguimiento. Se clasificó a los pacientes según el estadiaje clínico y patológico después de la biopsia y se obtuvieron datos sobre su tratamiento y pronóstico.Resultados: Durante un período de cinco años aproximadamente se obtuvieron datos de 77 sujetos con diagnóstico de melanoma maligno, no existieron diferencias en la presentación por sexo (hombres 49,3% frente a mujeres 50,7%), y edad (hombres 68,5 años frente a mujeres 65,7 años). El tipo de melanoma maligno más frecuente en mujeres fue el melanoma maligno de extensión superficial (58,9%) y en hombres el melanoma invasor (42,1%), el tratamiento más frecuente fue la escisión y cierre directo en los casos menos severos, mientras que en estadiajes severos fue la escisión seguida de injerto. Conclusiones: El melanoma maligno es un tipo de cáncer que en nuestro medio afecta por igual a hombres y mujeres, sin embargo, en el Ecuador parece ser que se manifiesta con mayor severidad en los hombres. Las características clínicas de este tipo de patología retrasan el diagnóstico, por lo que es necesario educar a la población para la detección temprana de lesiones sospechosas de melanoma maligno.
Pride’s “This Bed’s Not Big Enough”: Struggle for marital true love
Authors: Nurhamidah Idha , Purwanto Sugeng
Published: March 2020

The current study was aimed at investigating the struggle of Charley Pride through his song lyric entitled “This Bed’s Not Big Enough” employing a mixed approach of literary and systemic-functional perspectives to save his marriage in an alternative. The marital problem may go even worst when the memories linger in bed, calling his or her ex’s name on sexual encounters. This really hurts, and may or may not end in a divorce depending on the wife's decision. Upon completion of systemic functional linguistic analysis to construe the meaning of the song, it turns out that the song lyric managed to create a discursive practice that most people would experience when encountered in the same situational context. The solution varies from one individual to another pertinent to one's social and educational background. Therefore, to further confirm the research findings, a supplementary survey to twenty male colleagues (husbands) was conducted to reveal their attitude- moral values and judgments on both implicit and explicit intentions of the song, to extrinsically relate them to a social and religious domain (value). The findings show that alternative solutions differ from one individual to another depending on social, educational and religious backgrounds.
Venn-diagram strategy in EFL class to enhance learners’ writing skill and motivation
Authors: Syafii Muhammad Lukman , Miftah M. Zaini
Published: March 2020

This classroom action research was intended to enhance students' skills and motivation in writing report texts by implementing the Venn-diagram strategy. Twenty-one students failing to achieve the passing grade level of scores on their writing skills at the ninth grade of an Islamic secondary school in East Java Indonesia became the subjects of the study. The observation checklist, field notes, questionnaires, and writing test were used to collect data through implementing the Venn-diagram strategy taking a two-set circle and applying the writing process – prewriting via generating ideas, selecting relevant ideas, and ordering ideas; drafting general classification and description paragraphs; revising the rough draft and editing it; and publishing a final version. The results showed that the strategy can enhance the learners’ skills and their motivation in writing report text. The learners’ writing scores significantly increased both in two cycles – thirteen learners of the twenty-one students passed from the passing grade level in Cycle 1, and all learners passed from those in Cycle 2. It also highly motivates learners in writing report text, both in two cycles. Therefore, English teachers are recommended to apply Venn-diagram strategy in EFL writing class to start writing.
EAP alignment in EFL writing courses towards developing student’s academic writing skills
Authors: Workie Melaku Bayu , Haregu Zelealem Shitahun
Published: March 2020

The objective of the present study was to assess the prevailing alignment of English for academic purposes (EAP) in EFL writing courses vis-à-vis the development of academic writing skills of students in public universities of Amhara National Regional State (ANRS) in Ethiopia. The study used a descriptive survey that involved quantitative and qualitative methods. A questionnaire, focus-group discussions, and syllabus and materials survey were used to gather primary and secondary data, respectively, for the study. The descriptive statistics were employed in analyzing the quantitative data. The qualitative data were analyzed and reported thematically. The results showed there were existed a comparable horizontal (cross-department) distribution pattern of common writing courses among the three universities; all learners in taking the common course 'Basic Writing Skills' in each university learnt with the same syllabus and material regardless of their fields of study. So, there was a poor alignment of writing courses with the target students' mainstream discipline (i.e., learning and discourse) both in terms of content and genre.
Cultural representation and intercultural interaction in textbooks of English as an international language
Authors: Putra Tomy Kartika , Rochsantiningsih Dewi , Supriyadi Slamet
Published: March 2020

The present study attempts to scrutinize the manifestation of cultures and intercultural interactions in English textbooks. It investigates three English textbooks for twelfth-grade students produced by three relatively major publishers in Indonesia by employing cultural content and intercultural interaction analysis. The findings show that the examined textbooks do not appropriately demonstrate cultural diversity in the international context as cultures of Indonesia and English-speaking countries have their dominancy. Also, the textbooks mostly demonstrate intercultural interactions in fragmented, limited, and superficial ways. Some recommendations are addressed for future textbooks authors and publishers as well as English teachers. The results suggest textbook publishers and authors include more the material about international culture and to provide more the demonstration of deep intercultural interaction. Moreover, teachers need to be creative by adding supplementary cultural materials to patch up the shortcomings of the textbooks.
Circadian rhythms of leukemia inhibitory factor in the blood of patients with essential hypertension
Authors: Radaeva O.A. , Simbirtsev A.S. , Gromova E.V. , Iskandiarova M.S. , Belyaeva S.V.
Published: March 2020

Leukemia inhibitory factor (LIF) exerts multidirectional effects in the setting of essential hypertension (EH). There is a mounting body of evidence refuting the postulate about identical STAT3 signaling in cardiomyocytes and endothelial/smooth muscle cells, which is important in the situation of extended exposure to gp 130 ligands (LIF in particular). At the same time, there are no reports on the circadian dynamics of peripheral blood LIF concentrations and possible secondary changes to the pathophysiological effects of this cytokine. This study aimed to analyze the circadian dynamics of LIF concentrations in the peripheral blood serum measured at 5 different time points in patients with stage II EH in the presence/absence of antihypertensive therapy and their relationship with the frequency of complications developing within a 5-year follow-up. Blood serum LIF was measured in 60 patients with stage II EH using ELISA at 8:00, 14:00, 20:00, 2:00, and 8:00 o’clock before putting the patients on antihypertensive therapy and one year after its onset. The identified patterns of diurnal LIF concentrations (a rise by ≥15% at 20:00, p < 0.001; a further rise by ≥22% peaking at 2:00, p < 0.001 relative to the values at 8:00) can be regarded as pathologic; their persistence after one year of antihypertensive therapy is a sign of EH progression and puts the patients at 6-fold risk for cardiovascular complications, including myocardial infarction and acute cerebrovascular events.
Reproducción social indí­gena, solidaridad económica y reciprocidad en la comunidad Qom de Pampa del Indio, Chaco
Authors: Colla Julia Lucía
Published: April 2020

En este artí­culo analizamos las experiencias de producción agrí­cola y hortí­cola de los pueblos originarios Qom que conforman el movimiento social Federación Nacional Campesina (FNC) de la localidad de Pampa del Indio (provincia de Chaco). En un contexto de dobleexclusión que impuso el desarrollo del capital en estos territorios, el objetivo es analizar la manera en que estas poblaciones se apropiaron de los programas de asistencia estatal e implementaron diversas estrategias para realizar prácticas campesinas que permitieron la reproducción social en sus territorios. Consideramos que el análisis de estas actividades permite comprender que el objetivo de estas comunidades es la reproducción social de la vida, la cual no se halla anclada a las nociones de rentabilidad, competencia en el mercado o acumulación de capital. El enfoque de abordaje es la etnografí­a y se han realizado entrevistas en profundidad a hombres y mujeres que integran la FNC y observación participante en diversas visitas a las chacras. Además, se utilizan fuentes secundarias para profundizar el análisis sobre las condiciones estructurales y de vida de estas poblaciones.
Tatalaksana Multidisiplin pada Kasus Obesitas Anak Remaja
Authors: Faradilah Andi , Jalaluddin Syatirah , Larasati Iip
Published: March 2020

Seorang anak, 15 tahun 4 bulan, memiliki berat badan 57 kg, tinggi badan 150 cm, dan indeks massa tubuh 25.3 kg/m¬2. Anak masuk rumah sakit dengan keluhan nyeri menelan. Anak didiagnosis dengan faringitis akut dan obesitas. Aktivitas fisik harian berupa aktivitas sekolah. Riwayat pola kebiasaan makan berupa snack rendah kalori, minuman kemasan, dan mie instan. Status gizi anak adalah gemuk dengan status gastrointestinal fungsional. Terapi gizi yang diberikan berupa edukasi pada anak mengenai jumlah dan jenis makanan serta peningkatan aktivitas fisik.
GAMBARAN PENGETAHUAN BIDAN TENTANG LOTUS BIRTH DI PUSKESMAS BARA-BARAYA, PUSKESMAS MAMAJANG, DAN PUSKESMAS BATUA MAKASSAR
Authors: Rahma Andi Sitti , Syam Ni'mayani
Published: March 2020

Lotus Birth merupakan metode persalinan dengan membiarkan tali pusat hingga terlepas sendiri secara alami. Metode persalinan ini masih menjadi kontroversi, baik dari segi manfaat maupun dari aspek tinjauan sosialnya, sehingga masih belum banyak diketahui dan dilakukan.Penelitian ini merupakan penelitian observasional untuk mengetahui tingkat pengetahuan bidan di beberapa Puskesmas di Makassar tentang sejarah, manfaat dan pelaksanaan Lotus Birth. Sampel adalah bidan yang bertugas di puskesmas Bara-Baraya, Puskesmas Mamajang dan puskemas Batua yang berjumlah 31 orang.Hasil yang diperoleh adalah sebanyak 54.84% responden dengan tingkat pengetahuan tentang Lotus Birth secara umum adalah kurang, 83,87% tingkat pengetahuan kurang tentang sejarah Lotus Birth, 58.06% tingkat pengetahuan kurang tentang manfaat Lotus Birth, dan 61,29% tingkat pengetahuan kurang tentang pelaksanaan Lotus Birth.Kesimpulan yang diperoleh adalah bahwa pengetahuan bidan tentang Lotus Birth masih kurang, baik pengetahuan secara umum, maupun pengetahuan tentang sejarah, manfaat dan pelaksanaan Lotus Birth.
Penilaian fungsi terhadap pembedahan pada spinal myeloma, sebuah serial kasus. Studi jangka pendek
Authors: Fauziani Anggi
Published: March 2020

Latar belakang: Multiple myeloma (MM) spinal menimbulkan nyeri, fraktur patologis dan kompresi medula spinalis sehingga menimbulkan defisit neurologis. Terapi standar untuk myeloma adalah radioterapi, tetapi terapi operatif semakin sering dilakukan terutama jika terjadi kompresi medula spinalis. Penelitian ini dilakukan untuk mengetahui efektifitas terapi operatif pada 9 pasien multiple myeloma.Metode : merupakan studi kohort rerospketif terhadap terapi operatif pada 9 pasien MM spinal. Di RSUP Hasan Sadikin Bandung. Gejala neurologis dinilai dengan klasifikasi Frankle, nyeri dinilai dengan Visual analogue scale,dilakukan analisa pada karakteristik populasi, teknik rekonstruksi dan komplikasi operasi, dilakukan follow up pasca operasi selama satu tahun.Hasil : Pada 9 pasien spinal MM terdiri dari 7 pria dan 2 wanita, berusia 56- 70 tahun. 4 pasien lesi di thorakal, 5 pasien lesi di lumbar. Skala nyeri rata-rata preoperatif 8,5 dan membaik postoperatif 3,8. Frankle meningkat pada pasien dengan teknik operasi dekompresi.Hasil : terapi operatif pada spinal multiple myeloma meningkatkan kualitas hidup pasien spinal multiple myeloma dengan berkurangnya nyeri dan perbaikan defisit neurologis.   Kata kunci : Multiple Myeloma, Spinal, Operatif
HUBUNGAN KONFORMITAS DENGAN PROKRASTINASI AKADEMIK PADA MAHASISWA DI KOTA MAKASSAR
Authors: Andi Azis Trisnawaty
Published: March 2020

Penelitian ini bertujuan untuk mengetahui hubungan konformitas dengan prokrastinasi akademik pada mahasiswa di kota Makassar, jumlah responden sebanyak 184 orang. Data penelitian diperoleh dengan menggunakan kuesioner berdasarkan skala Likert. Kuesioner tersebut dianalisis berdasarkan metode deskriptif kuantitatif yang memenuhi persyaratan validitas dan realibilitas yang menggunakan corellation product moment person dengan bantuan komputerisasi.Berdasarkan analisis yang telah dilakukan menunjukkan bahwa konformitas mempunyai hubungan yang kuat dan signifikan dengan prokrastinasi akademik pada mahasiswa. Besarnya korelasi antara konformitas dengan prokrastinasi akademik adalah 0,224. Dengan demikian, maka besarnya kontribusi konformitas dengan prokrastinasi akademik mahasiswa adalah sebesar 9,6 % sedangkan sisanya 90,4 % ditentukan oleh variabel lain. Besarnya tingkat signifikansi koefisien korelasi adalah 0,002 yang di ukur dari probabilitas. Karena probabilitas jauh di bawah standar signifikan 5 % atau 0,05 maka konformitas dengan prokrastinasi akademik memiliki hubungan yang sangat kuat (signifikan) dengan prokrastinasi akademik pada mahasiswa di Kota Makassar
KEJADIAN HIPERTENSI (Studi Analitik Pada Pasien Dewasa di Wilayah Kerja Puskesmas Jongaya Kota Makassar)
Authors: Bagu Andi Alim
Published: March 2020

Hipertensi merupakan salah satu penyakit tanpa gejala atau the silent disaese. Hipertensi adalah keadaan dimana tekanan darah sistolik ≥140 mmHg dan diastolik ≥90 mmHg. Penelitian ini bertujuan untuk mengetahui kejadian hipertensi pada umur, aktivitas fisuk, makanan asin atau garam, obesitas, keturunan atau gen dan stres dengan kejadian hipertensi. Penelitian ini menggunakan deskriptik analitik dengan pendekatan study cross sectional dengan sampel sebanyak 179 responden dengan teknik pengambilan sampel dengan secara purposive sampling. Sedangkan sampel penelitian ini adalah pasien yang berkunjung di Puskesmas Jongaya dengan kriteria umur 25-45 tahun. Penelitian ini dilakukan di Puskesmas Jongaya Kecematan Tamalate Kota Makassar pada bulan Juni-Juli 2019. Berdasarkan hasil penelitian didapatkan bahwa ada hubungan antara umur, aktivitas fisik, makanan asin atau garam, obesitas, keturunan atau gen dan stres dengan kejadian hipertensi dengan nilai P= 0,000 < α = 0,050; P= 0,003 < α = 0,050; P= 0,008> α= 0,050; P= 0,004 < α = 0,050; P= 0,001> α= 0,050 dan P= 0,001> α= 0,050. Pada penelitian ini disarankan bagi masyarakat yang terkena penyakit hipertensi untuk selalu melakukan pemeriksaan 2 kali dalam semingu, untuk melakukan olaraga, menghindari makanan berminyak atau berlemak, mengkonsumsi kadar garam yang cukup dan melakukan pola hidup sehat.
Analisis Kesalahan Siswa dalam Menyelesaikan Soal Matematika pada SMA Pedesaan dan SMA Perkotaan
Authors: Djawa Yani , Asma Satri , Taher Tamrin
Published: March 2020

Abstract:Student errors in solving Mathematical problems are often found by writers in rural schools, and it possibly happened in schools in the city too. This article tries to analyze the mistakes of high school students in rural and urban areas in solving math problems. This research is qualitative with a research location in two schools, each as an interpretation of schools in rural and urban areas. The results found that students in a rural and urban school in principle there an error in solving problems. High school students in urban areas tend to make procedural errors while rural high school students in addition to making procedural errors also tend to make computational skills mistakes. Abstrak:Kesalahan siswa dalam menyelesaikan soal-soal Matematika sering penulis temukan pada sekolah di pedasaan, namun demikian tidak menutup kemungkinan juga terjadi pada sekolah di perkotaan. Artikel ini mencoba menganalisis kesalahan siswa SMA di Pedesaan dan Perkotaan dalam menyelesaikan soal matematika. Jenis penelitian yang digunakan adalah kualitatif dengan loaksi penelitian di dua sekolah yang masing-masing sebagai interpretasi sekolah yang berada di pedesaan dan perkotaan. Hasil penelitian diperoleh bahwa siswa yang bersekolah di pedesaan maupun perkotaan pada prinsipnya ditemukan adanya kesalahan dalam menyelesaikan soal. Siswa SMA di perkotaan cenderung untuk melakukan kesalahan prosedur sedangkan siswa SMA di pedesaan selain melakukan kesalahan prosedur juga cenderung melakukan kesalahan keterampilan komputasi.
Pengaruh Model Pembelajaran Kooperatif Tipe Index Card Match terhadap Hasil Belajar Matematika Siswa
Authors: Hartiningrum Esty Saraswati Nur , Ula Ni’matus Sa’adatul
Published: March 2020

Abstract:Learning will be more meaningful if students are given the opportunity to participate in various learning activities, students can actualize their abilities inside and outside the classroom. Choosing the right learning model can create an atmosphere fun and impact on student activities and learning outcomes. The Index Card Match type cooperative learning model is to find pairs of cards that are quite fun to use to exercises about the material that has been given. The purpose of this study is to determine whether there is influence of cooperative learning model index card match type on student learning outcomes. The research method uses pre-experimental designs with one-group pretest-posttest design models. Technical analysis using hypothesis testing, namely the t-test and correlation, the requirement to do the t-test is to do a normality test. The results of data analysis showed that there was the influence of the Index Card Match type of cooperative learning model on the mathematics learning outcomes of eighth grade students of Sumobito State Junior High School 2. SPSS calculation states that the value of r count = 0.709, which is located between 0.600 <r≤0.800 which means that it is in the high criteria. Abstrak:Belajar lebih bermakna apabila siswa diberi kesempatan berpartisipasi dalam kegiatan belajar, mengaktualisasikan kemampuan mereka di dalam dan di luar kelas. Memilih model pembelajaran yang tepat dapat menciptakan suasana yang menyenangkan dan berdampak pada kegiatan siswa dan hasil belajar. Model pembelajaran kooperatif tipe Index Card Match menyenangkan digunakan untuk mengulang materi yang telah diberikan. Penelitian ini bertujuan untuk mengetahui pengaruh Index Card Match terhadap hasil belajar siswa. Metode penelitian menggunakan desain pra-eksperimental dengan model desain pretest-posttest satu kelompok. Uji hipotesis dilakukan dengan uji-t dan korelasi. Hasil analisis data diperoleh terdapat pengaruh tipe Index Card Match terhadap hasil belajar matematika siswa. Perhitungan SPSS menyatakan bahwa nilai r hitung = 0,709, yang terletak di antara 0,600 <r≤0.800 yang berarti berada dalam kriteria tinggi.