bluuebunny/crossref_metadata_2025 huggingface dataset:
Opportunities to improve the effectiveness of complex treatment of optic neuritis of herpesvirus etiology
Authors:   The S. Fyodorov Eye Microsurgery Federal State Institution, the Khabarovsk Branch, Khabarovsk, Russian Federatio, Povalyaeva D.A. , Kolenko O.V. ,   The S. Fyodorov Eye Microsurgery Federal State Institution, the Khabarovsk Branch, Khabarovsk, Russian Federatio,   Postgraduate Institute for Public Health Workers, Khabarovsk, Russian Federation, Danilova L.P. ,   The S. Fyodorov Eye Microsurgery Federal State Institution, the Khabarovsk Branch, Khabarovsk, Russian Federatio,   Postgraduate Institute for Public Health Workers, Khabarovsk, Russian Federation, Makarova T.E. ,   Postgraduate Institute for Public Health Workers, Khabarovsk, Russian Federation, Emanova L.P. ,   The S. Fyodorov Eye Microsurgery Federal State Institution, the Khabarovsk Branch, Khabarovsk, Russian Federatio
Published: November 2022

Purpose. Evaluation of morphofunctional and laboratory-immunological results of the use of immunotherapy in the complex treatment of optic neuritis (ON) associated with herpesvirus infection (HVI). Material and methods. 39 people (39 eyes) with acute ON associated with HVI. The treatment regimen included the appointment of a dexamethasone solution according to a decreasing scheme, a 1 % solution of the drug «Emoxipin» 0.5 ml and a 12.5 % solution of the drug «Dicynone» 0.5 ml through an irrigation system implanted in the retrobulbar space, in combination with the prescription of drugs neuroprotection («Pikamilon» and «Semax») for 10 days. All patients were divided into 2 groups. The main group – 22 patients, in the treatment regimen of which the drug «Imunofan» was added. The control group included 17 patients who received standard treatment. Immunotherapy was carried out for 10–12 days. Results. Data analysis showed that the most significant positive dynamics was noted in patients of the main group. Conclusion. The clinical efficacy of the drug «Imunofan» in the complex therapy of ON associated with HVI was characterized by a reduction in the time for relief of signs of inflammation in the optic nerve by 2 times or more, an increase in the maximum corrected visual acuity by 4.5 times, a decrease in the incidence of relapses of ON by 2 times with follow-up period of 12 months. Keywords: optic neuritis, herpesvirus infection, corticosteroid therapy, immunotherapy
A clinical case of iridocyclitis similar the iris melanoma by the type of sago grains («tapioca»)
Authors:   Kirov state ophthalmology hospital, Podyninogina V.V. , Patrusheva I.N. ,   Kirov state ophthalmology hospital, Plotnikova Y.A. ,   Kirov state ophthalmology hospital
Published: November 2022

Iris melanoma by the type of sago grains («tapioca») is a rare form of malignant neoplasm that develops from melanocytes of the iris stroma. Early diagnosis of this disease is extremely important for the life and ability to work of patients. In a patient with chronic recurrent iridocyclitis, deposits of small calcifications were found on the cornea, long-standing opacities at the stroma level in the lower parts perilimbally, epitheliopathy in the form of small-point defects; multiple rounded nodules (neoplasms) of pale brown color on the iris OU. Diagnostic methods: ultrasound, gonioscopy, UBM, OST of the cornea, OST of the iris. Diagnosis: secondary calcifying ribbon keratopathy OS. Suspected iris melanoma of the type of sago grains («tapioca»), immature cataract, chronic iridocyclitis without exacerbation. Due to conservative treatment, including the use of glucocorticosteroids, the changes in the iris completely disappeared after 1.5 months. A clinical case demonstrates the possibility of developing one disease with manifestations of clinical symptoms of another nosological group disease. This implies a thorough differential diagnosis with the possible use of test therapy. Keywords: melanoma, chronic recurrent iridocyclitis, calcifications.
Multifocal choroiditis with choroidal neovascularization: case report and differential diagnosis
Authors:   Lomonosov Moscow State University, Faculty of Medicine, Department of ophthalmology, Moscow, Stulova A.N. , Troitskaya N.A. ,   Lomonosov Moscow State University Clinic, Moscow, Semenova N.S. ,   Lomonosov Moscow State University, Faculty of Medicine, Department of ophthalmology, Moscow, Akopyan V.S. ,   Lomonosov Moscow State University, Faculty of Medicine, Department of ophthalmology, Moscow
Published: November 2022

This is a retrospective case report of choroidal neovascularization (CNV) associated with multifocal choroiditis (MFC). We describe the results of a multimodal diagnostic approach and discuss differential diagnosis. In this patient the infectious causes of CNV were excluded and MFC was diagnosed. Intravitreal injection of aflibercept was recommended. Keyword: choroidal neovascularization, multifocal choroiditis, punctate inner choroidopathy, aflibercept
Features of the treatment of dry eye disease in patients with intermediate uveitis
Authors:   Siberian State Medical Univercity, Tomsk, Russia, Tatarnikova E.B. , Krivosheina O.I. ,   Siberian State Medical Univercity, Tomsk, Russia
Published: November 2022

Introduction. The development of inflammation and violations of the homeostasis of the tear film are of fundamental importance for the occurrence of dry eye disease (DED). In 28–57 % of cases, intermediate uveitis (IU) is accompanied by signs of irritation of the ocular surface and symptoms characteristic of DED. Purpose. Analysis of the effectiveness of complex treatment of DED and IU, including tear replacement and anti-inflammatory therapy in combination with laser retinal coagulation at the extreme periphery of the fundus. Material and methods. The results of treatment of 98 patients were analyzed: the main group – 78 patients – were prescribed complex treatment of DED, the comparison group – 20 patients – only local tear replacement and anti-inflammatory therapy. Evaluation of the effectiveness of the developed method of treatment of combined pathology was carried out after 3 and 6 months. based on the dynamics of OSDI indices, hyperemia of the bulbar conjunctiva, LIPCOF test and Norn test. Results. The use of complex treatment of DED in patients with IU contributes to a statistically significant (p < 0.05) decrease in signs of discomfort according to the results of OSDI to 34.8 %, a decrease in the bulbar conjunctiva hyperemia index to 51.4 %, a decrease in the LIPCOF test index to 22.2 %, an increase in tear film rupture time to 23.3 % with stable CP relief for 6 months observations. Conclusions. Thus, the results obtained clearly demonstrate the effectiveness of the use of complex treatment of DED in patients with IU. The developed method contributes not only to increasing the stability of the tear film, but also to reducing subjective feelings of discomfort and ensuring relief of inflammation at the extreme periphery, which allows us to recommend its wide application. Keywords: dry eye disease, intermediate uveitis, laser coagulation of the extreme periphery of the retina
Clinical case of treatment of a patient with sympathetic ophthalmia
Authors:   Cheboksary Branch of the S. Fedorov Eye Microsurgery Federal State Institution, Cheboksary, Grigorieva I.N. , Voskresenskaya А.А. ,   Cheboksary Branch of the S. Fedorov Eye Microsurgery Federal State Institution, Cheboksary, Pashtaev N.P. ,   Cheboksary Branch of the S. Fedorov Eye Microsurgery Federal State Institution, Cheboksary,   The Chuvash State University named after I.N. Ulyanov, Cheboksary
Published: November 2022

The clinical case of observation and treatment of patient M., 45 years old, who received in 2011 an open injury of the right eye with a metallic intraocular foreign body, complicated by damage to the lens and hemophthalmos. Primary surgical treatment with diascleral removal of the foreign body was performed on the same day. Subsequently, repeated surgical interventions, including vitreoretinal ones, were performed on the injured eye. 11 years after the injury, the patient was diagnosed with chronic sympathetic uveoneuroretinitis in the left eye. The right eye was enucleated, immunosuppressive therapy was prescribed (systemic therapy with glucocorticosteroids in the form of pulse – therapy with transfer to tablet forms, cyclosporine A). Taking into account the posterior form of sympathetic ophthalmia, verification of the diagnosis at an advanced stage, late start of immunosuppressive therapy, its delayed effect, a strictly individual scheme of long-term controlled treatment of the patient with monitoring of his ophthalmological and somatic status is necessary. Keywords: sympathetic ophthalmia, open globe injury, enucleation, immunosuppressive therapy
Clinical case of cavernous sinus thrombosis in a young patient after suffering COVID-19
Authors:   NJC Kazakh-Russian Medical University, Almaty, Abdullina V.R.
Published: November 2022

The article presents a clinical case of cavernous sinus thrombosis after suffering COVID-19 with complaints of decreased visual acuity and signs of papilledema Hypercoagulability associated with COVID-19 is caused by an active immune response to infection and may predispose to the development of a thromboembolic event in the cavernous sinus. Thus, close attention should be paid to patients' complaints of visual impairment caused by coronavirus infection. Clinical manifestations of cavernous sinus thrombosis may appear some time after the infection due to the possible long-term circulation of this virus in the body, activating immune complexes that cause cavernous sinus thrombosis, followed by the manifestation of ophthalmic symptoms. Keywords: cavernous sinus thrombosis, COVID-19, optic neuropathy, papilledema
SEBERAPA PENGARUH PENETAPAN NISBAH BAGI HASIL, INFLASI, DAN JUMLAH UANG BEREDAR TERHADAP DEPOSITO MUDHARABAH DI INDONESIA
Authors: Wahyu Fauziah Nafisah , Segaf
Published: November 2022

Tujuan dari penelitian ini adalah untuk menganalisis serta menguji pengaruh nisbah bagi hasil, inflasi serta jumlah uang beredar (JUB) terhadap deposito mudharabah pada Bank Muamalat Indonesia baik secara simultan maupun parsial periode tahun 2014-2021. Jenis penelitian ini yaitu kuantitatif dengan studi penelitian pada Bank Muamalat Indonesia dengan menggunakan metode pengumpulan data berupa purposive sampling. Sampel dalam penelitian ini 32 data yang meliputi data keuangan BMI serta data inflasi maupun JUB dari website resmi Bank Indonesia serta Badan Pusat Statistik. Hasil penelitian secara parsial menghasilkan variabel nisbah bagi hasil yang terbukti berpengaruh terhadap deposito mudharabah pada BMI. Sedangkan variabel Inflasi dan JUB terbukti tidak berpengaruh terhadap deposito mudharabah pada BMI. Uji parsial menghasilkan bahwa variabel nisbah bagi hasil, inflasi maupun JUB secara simultan berpengaruh terhadap deposito mudharabah. Hal ini menunjukkan pentingnya perbankan syariah untuk memfokuskan kebijakan pada nisbah bagi hasil yang ditawarkan kepada nasabahnya dan tidak terpengaruh pada situasi keuangan eksternal dalam aspek inflasi dan JUB.
Urban Growth Prediction by Land Suitability Index for Erbil City using Remote Sensing data, road networks and GIS Techniques
Authors: Al-Mamany Dler A. , Hameed Ali Hussein , Muhauwiss Farouk M. , Noori Abbas Mohammed
Published: November 2022

Using remote sensing data and Geographical Information System (GIS) methods, this study tries to anticipate the optimal urban expansion areas in Erbil city. The Analytical Hierarchy Process (AHP) concept was used to create a map of urban expansion. Several social, economic, environmental, utility and physical characteristics including land cover, roads, slope, aspect, elevation, soil texture, power lines, water and exclusion, were combined to construct a final land suitability index map. ASTER Digital Elevation Model (DEM) was also followed to derive slope and aspect variables. While organic growth is prominent, considerable growth is expected to occur around the outskirts of current settlements. This research highlights the use of modelbased prediction of urban sprawl in the development of the city’s master plan and road network plan. The findings of this study can help planners and policymakers adopt preventative or regulating measures in advance and make better informed strategic decisions.
Biotransformation of stevioside to rebaudioside – A in suspension cells of Stevia: Applications of leaf extract in functional biscuits
Authors: Shahu R. , Nambiar P. , Jobby R. , Jha P.
Published: November 2022

The suspension culture of Stevia was conceived as a means of establishing a stevioside-producing cell line in vitro. The highest callus induction rate (90%) was achieved using the Stevia leaf explants in modified MS medium supplemented with 1 mg/L BAP and 2 mg/L NAA. Friable and rapidly growing suspension cells were established in this media. The growth curve of suspension culture was studied by determining its biomass accumulation in PCV where the maximum biomass was obtained after 3 weeks. The suspension culture was preferred over callus culture for the biotransformation. The results indicated the simplicity, relatively inexpensive, eco-friendly nature of the process by showing 37.5% conversion of stevioside to rebaudioside A. As a result, it appears to be a potential method for the large-scale industrial synthesis of rebaudioside-A. This high biotransformation efficiency will be useful in substituting sucrose in functional foods. In the current study, the sensory characteristics and energy values of the biscuits containing Stevia, as a sugar replacement, were investigated. According to our findings, Stevia extract may be utilized as a natural sweetener in a variety of food products such as biscuits. In addition, these functional biscuits may be beneficial in maintaining good health, managing obesity and diabetes in patients.
Omicron and Delta variant spike protein mutations comparison and their interaction with ACE2 receptor
Authors: Vikram Kumar A. , Nazneen Bobby Md. , Srirama Krupanidhi
Published: November 2022

The current outbreak of coronavirus-associated disease characterized as coronavirus disease 19 (COVID-19) marked its existence in late 2019. Since then, it has been a concern for human health and safety. Coronaviruses (CoVs) are known to cause a wide range of diseases; out of which common cold and pneumonia occur in human beings. In this review, we elaborate on the basic characteristics, structure, variants mutations and the pathological attributes of SARS-CoV 2. We also discuss the interaction of the viral proteins with the host cell receptor known as the ACE2 receptor and various therapeutics for the treatment of disease.
Expression of cyclin D1 and its relation with t(11;14)(q13;q32) and trisomy 11 in multiple myeloma patients
Authors: Kalal Akanksha A. , Kumari Sucheta , Krishna Rajesh , Bhat Shubha P. , Shetty Prashanth
Published: November 2022

Multiple Myeloma (MM) is a haematological malignancy associated with various symptoms such as renal deficiency, anaemia, bone lesions and hypercalcemia. To elucidate the mechanism of cyclin D1 expression in MM patients, MM patients were evaluated for t(11;14)(q13;q32) by Interphase Fluorescence in situ hybridization (iFISH) and cyclin D1 expression by Reverse transcriptase-quantitative polymerase chain reaction (RT-qPCR).The incidence rate of t(11;14)(q13;q32) and trisomy 11 was 6% and 15% respectively. Cyclin D1 expression was higher in cases than controls. t(11;14) positive and trisomy 11 patients showed higher expression than patients without t(11;14) and trisomy 11. We found that t(11;14)(q13;q32) was associated with calcium and creatinine. A positive correlation was seen between cyclin D1 expression and globulin and a negative correlation between cyclin D1 and sodium levels.Our study indicated that other than t(11;14), trisomy 11 is also associated with overexpression of cyclin D1. Therefore, identifying a gene expression and its association with trisomy 11 indicate novel therapeutic targets.
Biosynthesis, characterization, toxicity assessment and bio-efficacy of silver nanoparticles synthesized by Microbacterium mitrae in controlling early blight in tomato (Lycopersicon esculentum L.)
Authors: Duhan J.S. , Bansal P. , Sadh P.K. , Kumar R. , Kumar A.
Published: November 2022

This study evaluated the biogenesis of silver nanoparticles (NPs) using Microbacterium mitrae and its possibilities against phytopathogens. Silver nanoparticles have been synthesized using a simple protocol and the synthesized NPs have been characterized using UV visible spectroscopy, particle size analyzer, transmission electron microscope (TEM). Small-sized, stable silver nanoparticles in the range of 10-25 nm have been reported. Their antimicrobial activity against three phytopathogens i.e. Alternaria solani, Thanatephorus cucumeris and Botryodiplodia theobromae, was studied. The nanoparticles showed effective antimicrobial activity against all the tested fungal pathogens under in vitro conditions. The genotoxicity of NPs was also studied using sister chromatid exchange analysis on human lymphocytes and no adverse effects were observed up to the concentration of 100μg/ml. Efficient control against early blight has been observed within cytotoxicity limits in pot study, preventing the disease outbreak in tomato plants.
Expression analysis of efflux gene Rv1634 in drug resistance Mycobacterium tuberculosis isolates
Authors: Kushwaha Ravindra , Kumar Rajeev , Kushwaha Ram Awadh Singh
Published: November 2022

Drug resistant tuberculosis (DR-TB) is a serious health issue worldwide and a number of mechanisms have been suggested which are involved in developing resistance in Mycobacterium tuberculosis to anti-tuberculosis drugs. In the Indian perspective, the pattern and prevalence of drug-resistant tuberculosis (DR-TB) are heterogeneous across regions and settings. Notably, isoniazid (INH), rifampicin (RIF) and ethambutol (EMB) are the most effective drugs in tuberculosis therapy. Understanding the pattern of resistance to these drugs in the Indian population is essential in quick diagnosis of multidrug-resistant (MDR) tuberculosis and extensive DR-TB (XDR-TB). A total of 36 Mycobacterium isolates from the North Indian population were exposed and tested for drug susceptibility with INH, RIF and EMB in vitro and results showed that 25, 24 and 24 isolates were resistant to INH, RIF and EMB respectively. Gene expression analysis revealed that approximately 50% of isolates under the stress of these three anti-tuberculosis drugs showed overexpression of efflux gene Rv1634. Moreover, overexpression of gene Rv1634 contributes to the emergence of drug resistance in M. tuberculosis and inhibition of Rv1634 along with other efflux pump genes and may provide a promising strategy for improving tuberculosis treatment outcomes in North India.
Phyco-chemical and compound analysis from the macro algae, Sargassum ilicifolium and its antibiofilm, antioxidants and Aedes aegypti mosquito larvicidal propensities
Authors: Archana Lakshmanan , Saranya Karuppannan , Balasubramani Govindasamy , Viji Maluventhan , Maruthupandian Arumugam
Published: November 2022

The well-known fact about marine natural resources is that they are made up of physiologically and structurally diverse secondary metabolites, particularly seaweed. These unique phytochemicals play a vital role in drug discovery. Currently, the antibacterial and larvicidal potential of targeted extracts of the brown algae Sargassum ilicifolium are being investigated. The bio-chemicals, namely tannins, saponin, phenolics, flavonoids, alkaloids, carbohydrates, glycosides and steroids, were qualitatively analyzed in the methanolic extract of S. ilicifolium (MESI). The quantitative analysis revealed the probable amount of biochemicals present in MESI viz. carbohydrates (620±2.20), proteins (330±1.70), alkaloids (77.6±1.17mg/g), phenols (47.3±0.90), lipids (45.2±1.12) and flavonoids (5.2±0.50 mg/g). The different functional groups present in MESI were identified based on the characteristic frequency peaks. From GC-MS study, totally 9 major bioactive compounds from the MESI were identified. Furthermore, the antimicrobial activities of the MESI have liberated the maximum activity against the tested gram-positive and negative bacteria.
Green approach for the synthesis of benzimidazoles using Malic acid as catalyst
Authors: Deka Nabajyoti , Talukdar Hrishikesh
Published: November 2022

An efficient malic acid catalyzed method has been developed for the synthesis of 2-substituted benzimidazoles in one step. The present method excludes the usage of any metal catalysts to produce benzazoles in good to excellent yields.
An Electrochemical Study by using Conductivity Measurement for Two Oximes at Different Temperatures supported with DFT Analysis
Authors: Al-Khayat R.Z. , Al-Dabbagh A.B. , Abdulrahman H.A. , Abdulrahman Sh.H.
Published: November 2022

The structure of oximes was proved by using available physical methods included (Infrared, Ultraviolet spectra and melting points). The aim of this study was to evaluate the ionization constant by conductivity method at different temperatures. The thermodynamic parameters namely (ΔG, ΔH, ΔS) of ionization reaction of these oximes as determined and discussed in details. The antibacterial activity of these oximes was tested against some bacteria. Optimized structure, boundary molecular orbitals (HOMO and LUMO) and global reactivity descriptors were analyzed by DFT calculations.
Synthesis and environmental application of TTCHEA resin in effluent handling
Authors: Rathore Sawai Singh , Joshi Archana , . Hanuman , Gupta Vikal
Published: November 2022

Industrial effluents include significant amounts of heavy metals. The elimination of these ions causes great concern towards the environment. The flora and fauna of the aquatic and terrestrial environments are significantly impacted by rising levels of these metal pollutants in the environment. In order to develop new chelating resin, tamarind kernel powder was employed. TKP derivative of tertiary amine acts as metal ion exchanger cum a janitor for removal of harmful toxic metal ions from effluents of mineral and metallurgical industries. This study describes adsorption process for removal of toxic metal ions from wastewater. In dioxane medium, serine was bound to TKP backbone. The resulting ion exchange resin has been used for treatment of effluents. Interesting data were obtained showing the way in which various metal pollutants were removed throughout the depth of resin bed. FTIR methods have been used to describe the structure of the chelating resin.
Phytoconstituent estimation and LC-MS studies of field grown Withania somnifera (L.) Dunal root extract in Jharkhand and Bihar
Authors: Mahto Harishankar , Mahato Dipa , Sharma Hanuman Prasad
Published: November 2022

Plants in either raw form or their root extracts are utilized as complementary and alternative medicine in various disorders. The present study was undertaken for phytoconstituents estimation and to evaluate chemical compositions of methanolic extract of Withania somnifera (L.) Dunal (Ashwagandha) roots collected from BAU, Ranchi, Jharkhand and Sabour, Bhagalpur, Bihar. Phytochemicals through crude methanolic extract were analyzed in Ashwagandha roots. Alcoholic extract was prepared using Soxhlet extraction apparatus. On phytochemical evaluation, total phenolic, flavonoid, total tannin and alkaloids were estimated. Presence of bioactive components in extract was determined by Liquid Chromatography-Mass Spectrophotometry (ESI positive ion) technique. Qualitative screening of extract ensured the presence of alkaloids, phenols, tannins and flavonoids. Quantitatively these phytochemicals showed TPC (66.06 mg/gm), TFC (650.0 mg/gm), TAC (102 mg/gm) and TTC (5.89 mg/gm). However, the phytochemicals and yield did not accumulate in various fractions on polarity. This result was supported by LC-MS analysis which showed 17 definite peaks in their chromatogram but only 8 peaks offer a suitable approximation. Extract revealed forty five bioactive compounds where most of them were phenolic compounds, aryl propionic acid and cinnamide derivatives. Quantitative analysis of present phytochemical showed maximum quantity of TFC followed by TAC, TPC and TTC. On the other hand, presence of various bioactive compounds in root extract showed that plant is having very high medicinal value.
Synthesis, characterization and application of novel green chelating PE-TH resin in the removal of toxic metals from industrial effluents
Authors: Parveen Seema , Kauser Khusbhu , Bais Rajni , Saini Ram Lal
Published: November 2022

One of the world's most serious environmental issues is water contamination produced by toxic metal ions from industrial wastewater. Heavy metal contamination has posed a severe threat to human health and the environment due to its toxicity. To investigate this issue, water contaminated by industrial waste must be rectified with paramount importance. The necessity of generating innovative, environmentally safe remedies to ensure the security of human life and environment is recognized by green chemistry. The purpose of the present research is to synthesize the novel plant-based green chelating resin to trap toxic metal ions from industrial wastewater. The Psyllium Epichlorohydrin Tyrosin Hydroxamate (PE-TH) resin is prepared by crosslinking Psyllium with Epichlorochydrin and Tyrosine amino acid. The total ion exchange capacity (Q) obtained for PE-TH resin is 5.780meq/g. The adsorption coefficient ‘Kd' is obtained by employing the batch adsorption method. The PE-TH resin proved to be very efficient in removing predominantly Cu (II) and Ni (II) ions from the electroplating industry wastewater. The pH range of 7-7.5 produced significant elimination of Cu (II) and Ni (II). The PE-TH resin satisfactorily adsorbs Cu (II) and Ni (II) metal ions from electroplating industry effluents. The newly synthesized PE-TH resin is easy to prepare and is eco-friendly, cost-effective and biodegradable green chelating agent to remove toxic metals ions efficiently from industrial effluents.
Isolation and Characterization of Gibberellin (GA-3) from Banana Blossom of Musa balbisiana Colla and Effect of The Isolate Addition on The Growth of Soybean (Glycine max) Plant
Authors: Fatharani Deika Zhillan , Ishmayana Safri , Hindersyah Reginawanti , Soedjanaatmadja Ukun M.S.
Published: November 2022

There is a type of banana that is unique because the flesh is filled with black seeds locally known as “pisang batu” (Musa balbisiana Colla). The objective of research was directed to determine the content of GA3 in banana blossom of M. balbisiana Colla and its effect on the growth of soybean (Glycine max) plant in vegetative and generative phase. GA3 was prepared by maceration followed by extraction using ethyl acetate and further purified using adsorption column chromatography and preparative TLC. The isolated product was then characterized using FTIR and HPLC. Sprouts of soybeans with uniform height were planted on polybags containing a mixture of planting media (soil: husk: manure = 3:2:1). The sprout was divided into five groups. The first group is the control only spraying with water, while others groups were treated by spraying GA3 isolate, crude extract, commercial Biostimulant and 1% NPK fertilizer. The soybean was determined for chlorophyll content of the leaf, proximate content and α-amylase activity. The results of HPLC and FTIR on gibberelline isolates showed a retention time and wave number which is relatively similar to the GA3 standard. GA3 levels in banana blossom of M. balbisiana Colla were 2.55 mg/g dry weight. The results of research showed that the GA3 isolate, crude extract and commercial biostimulant have significant effects on the growth of soybean plant both in the vegetative and generative phases for each parameter determined, proximate content, chlorophyll content and α-amylase activity compared to the control and NPK fertilizer.
Populationsgröße, Trichterdichte und Habitatpräferenz der Dünen-Ameisenjungfer Myrmeleon bore (Tjeder, 1941) im Gebiet der Dresdner Heide (Neuroptera)
Authors: Anselmi A. C. M. , Gallon S. C. E. , Müller P. , Reinhardt K.
Published: November 2022

Following the first record of Myrmeleon bore (Tjeder, 1941) in the Dresden Heath area in 2019 (KURTH 2020, Sächs. Entomol. Z. 10: 71-80), the population size and density of the species was determined. M. bore mainly was found in open, sparsely vegetated, sandy areas with direct sunlight exposure. The area-weighted density of the entire study site (4.05 hectares) was 0.177 larvae/m2. Population size estimates based on random quadrat counts lead to a figure of 4000-7000 individuals - the largest known population of this species. The positive correlation between larval size and pit diameter known for this species from laboratory trials was confirmed at our study site. This correlation may allow researchers to estimate the age structure of wild populations. Given the special responsibility of Germany for the protection of this species and the size of the population, we urge the protection of the site and a prioritisation over other protected species found in the area.
Design and Parametric Modeling of Pretensioned and Stiffened Membranes Project Work
Authors: Krasnopolskaia Iuliia
Published: November 2022

This research aimed to develop conceptually the pretensioned and stiffened membrane structures, using an experimental approach and computer simulation. The physical method of form finding included the pretensioned fabric with the glued grid made of the wooden sticks. Relaxation of the stressed membrane contributed to forming the specific anticlastic hyparic surface by energy release. The influence of the rigid elements pattern, intensity and direction of pretensioning on the final shape was investigated. The tensegrity structures were also built applying the same form finding way. These experiments led to the modelling of resulting samples with parametric design tools, namely Rhino and Grasshopper. Optimization of the final shape was carried out by changing parameters such as stiffenings configuration and membrane strength. This digital approach demonstrated successful simulation and rationalization of considered structures. Moreover, the final models can be used for further structural analysis and BIM. Considered membrane structures have very efficient load-bearing behavior. They are characterized by small weight, high light transmission and the ability to create large usable spaces free from columns. The most dangerous loads for membrane structures are wind and ponding. In practice, PTFE coated glass-fibre fabric and PVC coated polyester fabric are most suitable for pretensioned and stiffened membrane structures. The role of stiff elements can be played by steel profiles or metal tubes. The average time for the construction of a membrane structure is 6-15 months. Resulted pretensioned and stiffened membrane structures can be used as pavilions, roofs and awnings. They are distinguished by spectacular architectural view and very effective structural system. In addition, membrane tensile structures are characterized by high eco-efficiency and sustainability compared to other types of construction.
Nachhaltiges Bauen in der Praxis : Bewertung des Zertifizierungsprozesses der ökologischen Qualität nach DGNB System
Authors: Wuth Jasmin
Published: November 2022

Linking theory and practice, university research and the real economy, is a pillar of social development. With the financial support of the FOSTER program of the TU Dresden, I succeeded in this desired connection, even before the first dust on my thesis has settled down. With the support of the professorship for business administration, especially sustainability management and corporate environmental economics, I was able to transfer my diploma thesis from theory to practice, from the university to a renowned specialist journal. In my thesis, I dealt with the obstacles in the certification process of the German Sustainable Building Council (DGNB e.V.). The DGNB system in new buildings aims to ensure a holistic assessment of a building in terms of sustainable construction. I have examined which obstacles, from the point of view of the DGNB auditors, can arise in the course of the certification process when assessing ecological quality. Expert interviews with three auditors formed the basis for a structured questionnaire that was sent to all registered DGNB auditors. While the interviews served the explorative identification and systematisation of disruptive factors, the questionnaire empirically examined the extent to which these affect the course of certification over time and the achievement of the highest possible score. The interface cooperation and a late integration date of the DGNB concept in the planning of new buildings emerge as the most decisive obstacles. The analysis lays the foundation for overcoming any obstacles and can consequently make a contribution to optimizing the certification process. This can support building certification as a strategic instrument for sustainable building in establishing itself in the construction industry and increasing its market penetration. At the same time, this serves the overriding goal of promoting sustainable building methods and the construction industry. Further results will be published in an article in the specialist journal 'Bauingenieur' in 2021. So, in close coordination with the professorship and the FOSTER funding, I managed to keep my research in a drawer and to publish my results instead.
Life in plastic isn‘t fantastic Macroplastic effects on blue mussel aggregates in the inlet of Kerteminde Fjord, Denmark
Authors: Kumpitsch Luisa
Published: November 2022

Marine litter is a problem that effects a lot of different marine species, from mammals to invertebrates. It can have several destructing effects on marine ecosystems and is occurring on a global scale. The aim of my research in Kerteminde, Denmark, was to understand potential physiological and structural effects of marine plastic debris (= macroplastic) on aggregates of the blue mussel species Mytilus spp. It is common among these animals to build aggregates in intertidal and shallow subtidal habitats. They provide several ecosystem services, like stabilizing the shoreline or providing habitat for other species. Blue mussels are filter-feeders and so contributing to bioremediation, which is a key capacity to remove wastes from marine ecosystems. Considering the ecosystem services mussel aggregates provide, it is crucial to understand any factors that could harm this structure. My focus laid on the effects of rigid and soft macroplastic films, i.e. bottles and bags, as they represent common marine litter worldwide. I found that macroplastic indeed affects the structure of blue mussel aggregates. My project was part of a global study, organized by GEOMAR Kiel, where Master students from six countries conducted the same experiments to compare macroplastic effects on a global scale. I would like to thank the GAME program at GEOMAR Kiel for financing my research as wells as Dr. Mark Lenz for the organization of the project. Moreover, I want to thank the Marine Biological Research Center in Kerteminde for hosting me during my research.
Off Detailed Balance: Non-Equilibrium Steady States in Catalysis, Molecular Motors and Supramolecular Materials
Authors: Goldup Stephen , Aprahamian Ivan
Published: November 2022

All chemists are familiar with the idea that, at equilibrium steady state, the relative concentrations of species present in a system are predicted by the corresponding equilibrium constants, which are in turn related to the relative free energy difference of the system components. There is also no net flux between species, no matter how complicated the reaction network. Achieving and harnessing non-equilibrium steady states, by coupling a reaction network to a second spontaneous chemical process, has been the subject of work in a number of disciplines including the autonomous operation of molecular motors, the assembly of supramolecular materials, and strategies in enantioselective catalysis. Here we juxtapose these linked fields to highlight their common features, the similar issues that must be overcome, and some common misconceptions that may be serving to stymie progress.
Critical micelle concentration and partition coefficient of mixed micelles: Analysis of ternary systems based on Markov chain model and simple mixture model
Authors: Suzuki Nozomu , Taura Daisuke , Komichi Yuta
Published: November 2022

Hypothesis: When two or more surfactants are mixed, the mixed system exhibits improved performance compared with a single surfactant system in solution. The Markov chain model can analyze the critical micelle concentration (CMC) of mixed micelles, yielding results similar to those of a simple mixture model, which is typically referred to as the “regular solution theory.” In this study, two hypotheses were tested: (1) the Markov chain model for ternary systems can be simplified by approximating the association constant of surfactants i and j as Kij = Kji and (2) the quasi-simple ternary mixture model, that is, an analogous simple mixture model of the Markov chain model, helps interpret the interaction parameter of the simple mixture model that can describe the partition coefficient of the binary mixed micelle. Experiments: Equations were derived for (1) the Markov chain model for ternary systems by assuming Kij = Kji and (2) the interaction parameter of the simple mixture model that can describe the partition coefficient of the binary mixed micelle. Findings: The models were compared with the experiment data, and the derived equations described the experimental data of the CMC and partition coefficient well.
Fouling Resistance and Release Properties of Poly(sulfobetaine) Brushes with Varying Alkyl Chain Spacer Length and Molecular Weight
Authors: Khakzad Fahimeh , Dewangan Narendra , Li Tzu-Han , Safi Samghabadi Farshad , Herrera Monegro Ronard , Robertson Megan , Conrad Jacinta
Published: November 2022

We examined the effects of alkyl carbon spacer length (CSL) and molecular weight on fouling resistance and release properties of zwitterionic poly(sulfobetaine methacrylate) brushes. Using surface-initiated atom transfer radical polymerization, we synthesized two series of brushes with CSL = 3 and 4 and molecular weight from 19 - 1500 kg mol-1, corresponding to dry brush thickness from around 6 - 180 nm. The brush with CSL = 3 was nearly completely wet with water (independent of molecular weight), whereas the brush with CSL = 4 exhibited a strong increase in water contact angle with molecular weight. Though the two brush series had distinct wetting properties, both series of brushes exhibited similarly great resistance against fouling by Staphylococcus epidermidis bacteria and Aspergillus niger fungi spores when submerged in water, indicating that neither molecular weight nor carbon spacer length strongly affected the antifouling behavior. We also compared the efficacy of brushes against fouling by fungi and silicon oil in air. Brushes grafted to filter paper were strongly fouled by fungi and silicon oil in air. Grafting the polymers to the filter paper, however, greatly enhanced removal of the foulant upon rinsing. The removal of fungi and silicon oil when rinsed with a salt solution was enhanced by 219 and 175%, respectively, as compared to a blank filter paper control. Thus, our results indicate that these zwitterionic brushes can promote foulant removal for dry applications in addition to their well-known fouling-resistance in submerged conditions.
Silver-Catalyzed Tandem Cyclization for Syntheses of Azaoxa- and Diazaspirocycles
Authors: Shimaoka Momoka , Sai Masahiro
Published: November 2022

1-Azaspirocycles are important structures present in many drugs and natural products. This paper describes the silver-catalyzed tandem cyclization strategy, which provides atom-economical access to various azaoxa- and diazaspirocycles from alkynes containing two appended oxygen- and nitrogen-based nucleophiles. Intramolecular attack of the pendant nucleophile on the in situ-generated iminium intermediate is the key to the success of this transformation.
Photosensitizer Free Visible Light Synthesis of Multifunctional Coumarins from Trans-hydroxy acrylates
Authors: Roy Niladri Sekhar , Das Biswajit , Sarkar Debayan
Published: November 2022

A photosensitive and transition metal-free technique without inert gas shielding is reported for the facile synthesis of multifunctional coumarins. The current proce-dure avoids the inherent drawbacks of the previous coumarin production protocol in the presence of transition metal. The prominent aspects of the methodology also include the absence of photocatalyst, the absence of external additives including transition metals, and the employment of a straightforward precursor. Additionally, we went into great detail on the mechanistic investigation and utilization of multi-functional coumarins.
Best Available Parent and Duties of Justice
Authors: Walters Jordan
Published: November 2022

I argue that the best available parent view, in its present formulation, struggles to accommodate for our very weighty duty not to perpetuate historical injustices. I offer an alternative view that reconciles this tension.
Problems of organization and activities of guerrillas of Ukraine during the summer of 1941-1942 from the point of view of the modern western historiography
Authors: Prylutska Ludmila
Published: November 2022

The article analyzes the peculiarities of western scientists’ coverage of the problems of organization and effectiveness of the guerrilla movement in Ukraine, which, in their opinion, had a rather complex and ambiguous phenomenon. The role of various factors that took place in the creation and leadership of the detachments, including both the factor of upper leadership of the movement, and the factor of spontaneity, has been examined. The circumstances that served as an accelerator for its expansion in 1943 have been clarified; the thesis of the "nationwide struggle against the Nazi invaders", to which western scientists have always been skeptical, has been considered from a critical point of view. There are some contradictions in the works of historians of Western Europe, the United States, Canada and other countries to the estimation of the effectiveness of guerrilla action. The authors did not ignore the typical problems associated with the attitude of Soviet leaders to the seemingly excessive independence of the guerrillas. Western historians also clarify the relationship between the guerrillas and the local community, which has not always been cloudless. In addition, they constantly emphasize the indifference of guerrilla leaders to the events of Holocaust. Moreover, as a rule, partisans of Jewish origin often felt protected from anti-Semitic manifestations only in mono-ethnic Jewish detachments. The situation of girls and women guerrillas was rather difficult; many of them were forced to become mistresses of certain captains due to the aggressive behavior of male guerrillas. It should be highlighted that the classic work of D.A. Armstrong (1922-2010), Professor of the University of Wisconsin, "Soviet guerrillas. Legend and Reality, 1941-1944” stated that by the autumn of 1942 there were almost no guerrillas in Ukraine. The exceptions were the regions of Sumy and Chernihiv; according to his estimates, even at the beginning of 1943 there were no more than 20,000 guerrillas in Ukraine. It is noteworthy that the historical department of the US Army during the Cold War was monitoring closely the Soviet publications on the activities of Soviet guerrillas. In 1965 the bibliography of books, essays, memoirs, and collections of documents on the guerrillas group in the occupied territory of the USSR, which was collected there, figured up to 227 titles. Western scientists supported the formula of the "involuntary Resistance Movement" that existed in the occupied lands not only in Ukraine. According to them, the activities of the guerrillas had more psychological and political significance than purely military one - that is, the population should have felt that they were the representatives of the Soviet government.
The history of the Azov Battalion based on the materials of the Azov Battalion Archive of unregulated documentation (May-September 2014)
Authors: Kravchenko Mykola
Published: November 2022

The aim of the publication is to build a general scheme of the history of the Azov Volunteer Battalion, using the contents of the Azov Battalion Archive of unregulated documentation in general and internal battalion orders in particular.

The research methodology involves the application of the principles of historicism, the usage of studying whole historical sources and being objective. Descriptive method, methods of classification and systematization as well as methods of analysis and synthesis have been used. The source base of the study is based on internal battalion orders and other materials of the archive of unregulated documentation of the Azov Battalion.

The scientific novelty is conditioned by the high source value of the materials of the Azov Battalion Archive, which are currently completely unexplored within the academic science; these materials are introduced into scientific circulation for the first time.

The conclusions of the study are the construction the general scheme of a history of the Azov Volunteer Battalion from the establishment of the unit on May 5, 2014 on the basis of the training and mobilization center "Cossack Legion" in the actually squatted building in the center of the Ukrainian capital to expand the unit to the regiment of September 17, 2014. Important milestones in the battalion's history are the redeployment of the unit from Kyiv to the Azov coast, participation in hostilities in the summer and autumn of 2014, including the liberation of Mariupol on June 13 and Mar’inka on August 4, and participation in the Ilovaysk operation in August and the defense of Mariupol in early September of that year.
Analysis of the Design and Development Path of the Cultural and Creative Derivatives of Marquis of Haihun Site
Authors: Fang Yi
Published: November 2022

This paper firstly analyzes the culture of Marquis of Haihun site and explores the cultural and creative derivatives, followed by the value of these cultural and creative derivatives of Marquis of Haihun site and the design and development path of the cultural and creative derivatives of Marquis of Haihun site for the reference of relevant scholars.
Application of Nonlinear Triangular Fuzzy Fault Tree Algorithm in Predicting Lithium Battery Air Transport Accidents
Authors: Ji Lingling , Gu Zhengzhong
Published: November 2022

The traditional triangular fuzzy fault tree prediction model adopts the linear approximation method. Therefore, the accident prediction error is large. Based on the analysis of the error sources and the fuzzy set, the precise calculation method of the event at the top of the fault tree is given. By using the numerical calculation software, an accurate calculation method of nonlinear triangular fuzzy accident prediction was adopted to predict lithium battery air transport fire accidents, and the fuzzy importance of the cause event was calculated.