bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figure 4 from Mithramycin Represses Basal and Cigarette Smoke–Induced Expression of ABCG2 and Inhibits Stem Cell Signaling in Lung and Esophageal Cancer Cells
Authors: Zhang Mary , Mathur Aarti , Zhang Yuwei , Xi Sichuan , Atay Scott , Hong Julie A. , Datrice Nicole , Upham Trevor , Kemp Clinton D. , Ripley R. Taylor , Wiegand Gordon , Avital Itzak , Fetsch Patricia , Mani Haresh , Zlott Daniel , Robey Robert , Bates Susan E. , Li Xinmin , Rao Mahadev , Schrump David S.
Published: March 2023

PDF file - 363K, Ingenuity pathway analysis demonstrating two common networks targeted by mithramycin in lung cancer cells in vitro and in vivo
Supplementary Figure 3 from Mithramycin Represses Basal and Cigarette Smoke–Induced Expression of ABCG2 and Inhibits Stem Cell Signaling in Lung and Esophageal Cancer Cells
Authors: Zhang Mary , Mathur Aarti , Zhang Yuwei , Xi Sichuan , Atay Scott , Hong Julie A. , Datrice Nicole , Upham Trevor , Kemp Clinton D. , Ripley R. Taylor , Wiegand Gordon , Avital Itzak , Fetsch Patricia , Mani Haresh , Zlott Daniel , Robey Robert , Bates Susan E. , Li Xinmin , Rao Mahadev , Schrump David S.
Published: March 2023

PDF file - 346K, Ingenuity pathway analysis depicting representative intracellular networks modulated by mithramycin lung cancer xenografts
Supplementary Figure 4 from OTX2 Represses Myogenic and Neuronal Differentiation in Medulloblastoma Cells
Authors: Bai Ren-Yuan , Staedtke Verena , Lidov Hart G. , Eberhart Charles G. , Riggins Gregory J.
Published: March 2023

PDF file, 125K, Co-culturing of D425-GFP and C2C12-RFP cells, and the induction of myogenic and neuronal differentiation in D283 cells by OTX2 knockdown.
Supplementary Figure Legends 1-4, Table 1 from Loss of Fibroblast HIF-1α Accelerates Tumorigenesis
Authors: Kim Jung-whan , Evans Colin , Weidemann Alexander , Takeda Norihiko , Lee Yun Sok , Stockmann Christian , Branco-Price Cristina , Brandberg Filip , Leone Gustavo , Ostrowski Michael C. , Johnson Randall S.
Published: March 2023

PDF file - 107K
Supplementary Figure 3 from Loss of Fibroblast HIF-1α Accelerates Tumorigenesis
Authors: Kim Jung-whan , Evans Colin , Weidemann Alexander , Takeda Norihiko , Lee Yun Sok , Stockmann Christian , Branco-Price Cristina , Brandberg Filip , Leone Gustavo , Ostrowski Michael C. , Johnson Randall S.
Published: March 2023

PDF file - 169K, Deletion of Vhl, Hif-2� or Vegfa in Stromal Fibroblasts Does Not affect PyMT Mammary Tumor Growth.
Supplementary Figure 2 from Loss of Fibroblast HIF-1α Accelerates Tumorigenesis
Authors: Kim Jung-whan , Evans Colin , Weidemann Alexander , Takeda Norihiko , Lee Yun Sok , Stockmann Christian , Branco-Price Cristina , Brandberg Filip , Leone Gustavo , Ostrowski Michael C. , Johnson Randall S.
Published: March 2023

PDF file - 146K, Fibroblast Hif-1� Deletion Promotes Mammary Tumor Growth.
Supplementary Figure 6 from The Oncogenic Lung Cancer Fusion Kinase CD74-ROS Activates a Novel Invasiveness Pathway through E-Syt1 Phosphorylation
Authors: Jun Hyun Jung , Johnson Hannah , Bronson Roderick T. , de Feraudy Sebastien , White Forest , Charest Alain
Published: March 2023

PDF file - 173K, Elimination of E-Syt1 expression by RNAi does not abrogate CD74-ROS transformation activity
Supplementary Figure 5 from CXCR3+ T Regulatory Cells Selectively Accumulate in Human Ovarian Carcinomas to Limit Type I Immunity
Authors: Redjimi Nassima , Raffin Caroline , Raimbaud Isabelle , Pignon Pascale , Matsuzaki Junko , Odunsi Kunle , Valmori Danila , Ayyoub Maha
Published: March 2023

PDF file - 32K, Assessment of the ability of CXCR3+ MTreg to migrate toward CXCL10
Supplementary Figure 5 from The Oncogenic Lung Cancer Fusion Kinase CD74-ROS Activates a Novel Invasiveness Pathway through E-Syt1 Phosphorylation
Authors: Jun Hyun Jung , Johnson Hannah , Bronson Roderick T. , de Feraudy Sebastien , White Forest , Charest Alain
Published: March 2023

PDF file - 153K, Cells expressing oncogenic ROS fusion kinases are sensitive to ROS inhibitors
Supplementary Figure 4 from The Oncogenic Lung Cancer Fusion Kinase CD74-ROS Activates a Novel Invasiveness Pathway through E-Syt1 Phosphorylation
Authors: Jun Hyun Jung , Johnson Hannah , Bronson Roderick T. , de Feraudy Sebastien , White Forest , Charest Alain
Published: March 2023

PDF file - 111K, Cells expressing oncogenic ROS fusion kinases are sensitive to ALK/ROS inhibitors
Supplementary Figure 3 from CXCR3+ T Regulatory Cells Selectively Accumulate in Human Ovarian Carcinomas to Limit Type I Immunity
Authors: Redjimi Nassima , Raffin Caroline , Raimbaud Isabelle , Pignon Pascale , Matsuzaki Junko , Odunsi Kunle , Valmori Danila , Ayyoub Maha
Published: March 2023

PDF file - 52K, Combined analysis of CD25, CD127, FOXP3 and CXCR3 expression in OC CD4+ T cells
Supplementary Figure 3 from The Oncogenic Lung Cancer Fusion Kinase CD74-ROS Activates a Novel Invasiveness Pathway through E-Syt1 Phosphorylation
Authors: Jun Hyun Jung , Johnson Hannah , Bronson Roderick T. , de Feraudy Sebastien , White Forest , Charest Alain
Published: March 2023

PDF file - 160K, The ROS fusion kinases activate canonical growth and survival signaling pathways
Supplementary Figure 2 from CXCR3+ T Regulatory Cells Selectively Accumulate in Human Ovarian Carcinomas to Limit Type I Immunity
Authors: Redjimi Nassima , Raffin Caroline , Raimbaud Isabelle , Pignon Pascale , Matsuzaki Junko , Odunsi Kunle , Valmori Danila , Ayyoub Maha
Published: March 2023

PDF file - 46K, Assessment of CCR4 and CCR6 expression in peripheral and OC MTreg
Supplementary Figure 2 from The Oncogenic Lung Cancer Fusion Kinase CD74-ROS Activates a Novel Invasiveness Pathway through E-Syt1 Phosphorylation
Authors: Jun Hyun Jung , Johnson Hannah , Bronson Roderick T. , de Feraudy Sebastien , White Forest , Charest Alain
Published: March 2023

PDF file - 124K, The ROS fusion kinases localize to different compartments within cells
Supplementary Figure 1 from CXCR3+ T Regulatory Cells Selectively Accumulate in Human Ovarian Carcinomas to Limit Type I Immunity
Authors: Redjimi Nassima , Raffin Caroline , Raimbaud Isabelle , Pignon Pascale , Matsuzaki Junko , Odunsi Kunle , Valmori Danila , Ayyoub Maha
Published: March 2023

PDF file - 46K, Assessment of the differentiation stage of Treg and Tconv from PBMC and OC tumors
Supplementary Movie from Mice Expressing Activated PI3K Rapidly Develop Advanced Colon Cancer
Authors: Leystra Alyssa A. , Deming Dustin A. , Zahm Christopher D. , Farhoud Mohammed , Olson Terrah J. Paul , Hadac Jamie N. , Nettekoven Laura A. , Albrecht Dawn M. , Clipson Linda , Sullivan Ruth , Washington Mary Kay , Torrealba Jose R. , Weichert Jamey P. , Halberg Richard B.
Published: March 2023

WMP file - 834MB, The tumors in FC+ PIK3ca*+ mice exhibit high avidity for 124I-CLR1404. A mouse was injected with the imaging agent and then dual hybrid PET/CT colonography was performed. The agent was detected in all three tumors. This mouse is the same as shown in Figure 1, panels C and D. The agent was also detected in heart.
Supplementary Figures 1-4 from VEGF Receptor Inhibitors Block the Ability of Metronomically Dosed Cyclophosphamide to Activate Innate Immunity–Induced Tumor Regression
Authors: Doloff Joshua C. , Waxman David J.
Published: March 2023

PDF file - 667K
Supplementary Tables 1-6 from Impact of Intertumoral Heterogeneity on Predicting Chemotherapy Response of BRCA1-Deficient Mammary Tumors
Authors: Rottenberg Sven , Vollebergh Marieke A. , de Hoon Bas , de Ronde Jorma , Schouten Philip C. , Kersbergen Ariena , Zander Serge A.L. , Pajic Marina , Jaspers Janneke E. , Jonkers Martijn , Lodén Martin , Sol Wendy , van der Burg Eline , Wesseling Jelle , Gillet Jean-Pierre , Gottesman Michael M. , Gribnau Joost , Wessels Lodewyk , Linn Sabine C. , Jonkers Jos , Borst Piet
Published: March 2023

PDF file - 514K
Supplementary Methods from Impact of Intertumoral Heterogeneity on Predicting Chemotherapy Response of BRCA1-Deficient Mammary Tumors
Authors: Rottenberg Sven , Vollebergh Marieke A. , de Hoon Bas , de Ronde Jorma , Schouten Philip C. , Kersbergen Ariena , Zander Serge A.L. , Pajic Marina , Jaspers Janneke E. , Jonkers Martijn , Lodén Martin , Sol Wendy , van der Burg Eline , Wesseling Jelle , Gillet Jean-Pierre , Gottesman Michael M. , Gribnau Joost , Wessels Lodewyk , Linn Sabine C. , Jonkers Jos , Borst Piet
Published: March 2023

PDF file - 44K
Supplementary Figures 6-10 from Ploidy and Large-Scale Genomic Instability Consistently Identify Basal-like Breast Carcinomas with BRCA1/2 Inactivation
Authors: Popova Tatiana , Manié Elodie , Rieunier Guillaume , Caux-Moncoutier Virginie , Tirapo Carole , Dubois Thierry , Delattre Olivier , Sigal-Zafrani Brigitte , Bollet Marc , Longy Michel , Houdayer Claude , Sastre-Garau Xavier , Vincent-Salomon Anne , Stoppa-Lyonnet Dominique , Stern Marc-Henri
Published: March 2023

PDF file - 511K, Figure S6. Persistence and robustness of the discriminating �window� independently of the method of LSTs evalutation (supplementary to Figure 2B). Figure S7. Two tumors with similar total numbers of breakpoints. Figure S8. Distribution of LSTs along the genome, GC content and common fragile site for the chromosome bands with LSTs detected in more than 6 tumors. Figure S9. Somatic mutation in BRCA1 detected in two BLCs. Figure S10. LSTs in xenograft passages from GSE32530.
Supplementary Figure 6 from Soluble CD200 Is Critical to Engraft Chronic Lymphocytic Leukemia Cells in Immunocompromised Mice
Authors: Wong Karrie K. , Brenneman Fred , Chesney Alden , Spaner David E. , Gorczynski Reginald M.
Published: March 2023

PDF file - 69K, Engraftment of CD19+CD5+ CLL cells in peritoneal cavity: Absolute count (x105 cells) of CD19+CD5+ CLL cells in the peritoneal cavity of animals receiving either sCD200hi CLL plasma, or sCD200 absorbed CLL plasma in the presence or absence of T-cell depleting antibody OKT3 (infused iv)
Supplementary Figure 5 from Aptamer Identification of Brain Tumor–Initiating Cells
Authors: Kim Youngmi , Wu Qiulian , Hamerlik Petra , Hitomi Masahiro , Sloan Andrew E. , Barnett Gene H. , Weil Robert J. , Leahy Patrick , Hjelmeland Anita B. , Rich Jeremy N.
Published: March 2023

PDF file - 279K, Aptamer A4 high cells have a differential genetic profile associated with downregulation of genes involved in cellular development.
Supplementary Figure 3 from Aptamer Identification of Brain Tumor–Initiating Cells
Authors: Kim Youngmi , Wu Qiulian , Hamerlik Petra , Hitomi Masahiro , Sloan Andrew E. , Barnett Gene H. , Weil Robert J. , Leahy Patrick , Hjelmeland Anita B. , Rich Jeremy N.
Published: March 2023

PDF file - 226K, TIC-specific apatmers internalize specifically into TICs.
Supplementary Figure 2 from Endoneurial Macrophages Induce Perineural Invasion of Pancreatic Cancer Cells by Secretion of GDNF and Activation of RET Tyrosine Kinase Receptor
Authors: Cavel Oren , Shomron Olga , Shabtay Ayelet , Vital Joseph , Trejo-Leider Leonor , Weizman Noam , Krelin Yakov , Fong Yuman , Wong Richard J. , Amit Moran , Gil Ziv
Published: March 2023

PDF file - 79K, Characterization of macrophages according to the M1 and M2 terminology. Monocyte-derived human macrophages were incubated in three conditions: M-CSF; LPS and condition media from MiaPaCa2 (PDA-CM). We positioned the activated macrophages in the M1/M2 spectrum (classically activated/alternatively activated), by testing the expression of CD86 and CD163, typical M1 and M2 markers, respectively. (a) Incubation with LPS resulted in pure M1 (CD86-positive) population. (b) Incubation with M-CSF produced M2 (CD163-positive) population. (c) Incubation with PDA-CM resulted in mixed M1/M2 population.
Supplementary Methods from Immune Response Is an Important Aspect of the Antitumor Effect Produced by a CD40L-Encoding Oncolytic Adenovirus
Authors: Diaconu Iulia , Cerullo Vincenzo , Hirvinen Mari L.M. , Escutenaire Sophie , Ugolini Matteo , Pesonen Saila K. , Bramante Simona , Parviainen Suvi , Kanerva Anna , Loskog Angelica S.I. , Eliopoulos Aristides G. , Pesonen Sari , Hemminki Akseli
Published: March 2023

PDF file - 85K
Supplementary Figure 3 from VEGF-C and VEGF-D Blockade Inhibits Inflammatory Skin Carcinogenesis
Authors: Alitalo Annamari K. , Proulx Steven T. , Karaman Sinem , Aebischer David , Martino Stefania , Jost Manuela , Schneider Nicole , Bry Maija , Detmar Michael
Published: March 2023

PDF - 932K, Immunofluorescence staining of CD45+,CD4+ and CD45+,CD8+ T cells in DMBA-TPA treated skin of wild-type, control transgenic and transgenic mice.
Supplementary Table 1 from TERT Promoter Mutations Occur Early in Urothelial Neoplasia and Are Biomarkers of Early Disease and Disease Recurrence in Urine
Authors: Kinde Isaac , Munari Enrico , Faraj Sheila F. , Hruban Ralph H. , Schoenberg Mark , Bivalacqua Trinity , Allaf Mohamad , Springer Simeon , Wang Yuxuan , Diaz Luis A. , Kinzler Kenneth W. , Vogelstein Bert , Papadopoulos Nickolas , Netto George J.
Published: March 2023

PDF file - 8K, Table S1. TERT promoter mutation status in 59 pTa and 17 carcinoma in situ (CIS) patients.
Figure S5 from Growth of Triple-Negative Breast Cancer Cells Relies upon Coordinate Autocrine Expression of the Proinflammatory Cytokines IL-6 and IL-8
Authors: Hartman Zachary C. , Poage Graham M. , den Hollander Petra , Tsimelzon Anna , Hill Jamal , Panupinthu Nattapon , Zhang Yun , Mazumdar Abhijit , Hilsenbeck Susan G. , Mills Gordon B. , Brown Powel H.
Published: March 2023

Figure S5 - PDF file 1389K, Inducible inhibition of IL-6, IL-8, and CXCL1, and tandem inhibition of IL-6, IL-8, and CXCL1 in SUM159, MDA-MB-231, and MDA-MB-468 cells
Supplementary Table from CIP2A Modulates Cell-Cycle Progression in Human Cancer Cells by Regulating the Stability and Activity of Plk1
Authors: Kim Jae-Sung , Kim Eun Ju , Oh Jeong Su , Park In-Chul , Hwang Sang-Gu
Published: March 2023

PDF file, 70K, Correlation between CIP2A and Plk1 in human lung, cervical, gastric, and colon cancer specimens.
Figure S4 from Growth of Triple-Negative Breast Cancer Cells Relies upon Coordinate Autocrine Expression of the Proinflammatory Cytokines IL-6 and IL-8
Authors: Hartman Zachary C. , Poage Graham M. , den Hollander Petra , Tsimelzon Anna , Hill Jamal , Panupinthu Nattapon , Zhang Yun , Mazumdar Abhijit , Hilsenbeck Susan G. , Mills Gordon B. , Brown Powel H.
Published: March 2023

Figure S4 - PDF file 195K, Expression of ER� and its effect on IL-6, IL-8 and CXCR1 production in SUM159 cells
Supplementary Figure 7 from CIP2A Modulates Cell-Cycle Progression in Human Cancer Cells by Regulating the Stability and Activity of Plk1
Authors: Kim Jae-Sung , Kim Eun Ju , Oh Jeong Su , Park In-Chul , Hwang Sang-Gu
Published: March 2023

PDF file, 78K, CIP2A forms a multimer complex.
Supplementary Tables from Childhood Height and Body Mass Index Were Associated with Risk of Adult Thyroid Cancer in a Large Cohort Study
Authors: Kitahara Cari M. , Gamborg Michael , Berrington de González Amy , Sørensen Thorkild I.A. , Baker Jennifer L.
Published: March 2023

PDF file 75K, Supplementary Table 1. Hazard ratios and 95% confidence intervals for papillary and follicular thyroid cancer per 1-standard deviation score difference in height and BMI at each age from 7-13 years Supplementary Table 2. Hazard ratios and 95% confidence intervals for total thyroid cancer per 1-standard deviation score difference in height at each age from 7-13 years, by age at diagnosis Supplementary Table 3. Hazard ratios and 95% confidence intervals for total thyroid cancer per 1-standard deviation score difference in BMI at each age from 7-13 years, by age at diagnosis Supplementary Table 4. Hazard ratios and 95% confidence intervals for total thyroid cancer per 1-standard deviation score difference in height and BMI at each age from 7-13 years, mutually adjusted Supplementary Table 5. Hazard ratios and 95% confidence intervals for total thyroid cancer per 1-standard deviation score difference in height and BMI at each age from 7-13 years, restricted to participants with data on birth weight Supplementary Table 6. Hazard ratios of thyroid cancer by quintiles of change in height SDS between ages 7 and 13 years Supplementary Table 7. Hazard ratios of thyroid cancer by quintiles of change in BMI SDS between ages 7 and 13 years
Supplementary Figure 4 from TGF-β Mediates Homing of Bone Marrow–Derived Human Mesenchymal Stem Cells to Glioma Stem Cells
Authors: Shinojima Naoki , Hossain Anwar , Takezaki Tatsuya , Fueyo Juan , Gumin Joy , Gao Feng , Nwajei Felix , Marini Frank C. , Andreeff Michael , Kuratsu Jun-Ichi , Lang Frederick F.
Published: March 2023

PDF file - 5585K, Double staining for GFP and TGF-β detects BM-hMSCs-GFP near tumor cells expressing TGF-β in intracranial tumors.
Supplementary Figure 6 from Myeloid-Specific Expression of Ron Receptor Kinase Promotes Prostate Tumor Growth
Authors: Gurusamy Devikala , Gray Jerilyn K. , Pathrose Peterson , Kulkarni Rishikesh M. , Finkleman Fred D. , Waltz Susan E.
Published: March 2023

PDF file - 303K, Quantification of T-cells in tumors and spleens. For Review and Publication Both.
Supplementary Table 1 from Automated Tracking of Nanoparticle-labeled Melanoma Cells Improves the Predictive Power of a Brain Metastasis Model
Authors: Sundstrøm Terje , Daphu Inderjit , Wendelbo Ingvild , Hodneland Erlend , Lundervold Arvid , Immervoll Heike , Skaftnesmo Kai Ove , Babic Michal , Jendelova Pavla , Sykova Eva , Lund-Johansen Morten , Bjerkvig Rolf , Thorsen Frits
Published: March 2023

PDF file - 37K, Tumor take and mean number of tumors in the labeled 105, 5 x 105 and 106 groups and in the unlabeled 106 group at 4, 6 and 8 weeks post injection
Supplementary Figure 1 from Tissue Damage–Associated “Danger Signals” Influence T-cell Responses That Promote the Progression of Preneoplasia to Cancer
Authors: He Ying , Zha Jikun , Wang Yamin , Liu Wenhua , Yang Xuanming , Yu Ping
Published: March 2023

PDF file - 46K, Lymphocytes promote prostate cancer in TRAMP mice
Supplementary Figures 1 - 5 from MDM2 Small-Molecule Antagonist RG7112 Activates p53 Signaling and Regresses Human Tumors in Preclinical Cancer Models
Authors: Tovar Christian , Graves Bradford , Packman Kathryn , Filipovic Zoran , Xia Brian Higgins Mingxuan , Tardell Christine , Garrido Rosario , Lee Edmund , Kolinsky Kenneth , To Kwong-Him , Linn Michael , Podlaski Frank , Wovkulich Peter , Vu Binh , Vassilev Lyubomir T.
Published: March 2023

PDF file - 1272K, Comparison of MDM2 binding properties of RG7112 and nutlin-3a (S1); Overlay of the crystal structures of MDM2 bound to RG7112 and Nutlin-2 (S2); RG7112 is a non-genotoxic p53 activator (S3); Effect of RG7112 on the viability of HCT116 cancer cells and their p53-null clone HCT116R1 (S4); RG7112 blocks the proliferation of mouse NIH-3T3 cells (S5).
Supplementary Figure 8 from Therapeutic PD-1 Pathway Blockade Augments with Other Modalities of Immunotherapy T-Cell Function to Prevent Immune Decline in Ovarian Cancer
Authors: Duraiswamy Jaikumar , Freeman Gordon J. , Coukos George
Published: March 2023

PDF file, 20K, Combination therapy increases ovarian tumor antigen (mesothelin) specific inflammatory cytokine production by ID8 TILs.
Supplementary Figure 1 from Identification of an Aurora Kinase Inhibitor Specific for the Aurora B Isoform
Authors: Xie Hua , Lee Mee-Hyun , Zhu Feng , Reddy Kanamata , Peng Cong , Li Yan , Lim Do Young , Joon Kim Dong , Li Xiang , Kang Soouk , Li Haitao , Ma Weiya , Lubet Ronald A. , Ding Jian , Bode Ann M. , Dong Zigang
Published: March 2023

PDF file - 107K, HOI-07 inhibits Akt1 and Akt2 activities in vitro but not in cells. A and B, HOI-07 inhibits in vitro Akt1 (A) and Akt2 (B) kinase activities in a concentration-dependent manner. Akt1 and Akt2 kinase assays were performed using the liquid scintillation method. C and D, Western blot analysis of the expression of Akt downstream signaling molecules in A549 (C) and NCI-H520 (D) cancer cells. No obvious inhibitory activity on the Akt downstream pathway was observed after treatment HOI-07 for 2 h
Supplementary Table 1, Figure 1 - 6 from Soluble Carcinoembryonic Antigen Activates Endothelial Cells and Tumor Angiogenesis
Authors: Bramswig Kira H. , Poettler Marina , Unseld Matthias , Wrba Friedrich , Uhrin Pavel , Zimmermann Wolfgang , Zielinski Christoph C. , Prager Gerald W.
Published: March 2023

PDF file - 482K, Supplemental Table 1 displays patients' characteristics of paraffin-embedded tumor tissue sections analyzed in Figure 6D; Supplemental Fig.1 demonstrates tumor-vascularization of CEA-mimotop immunized mice; Supplemental Fig.2 displays Matrigel-invasion as well as CaKi2-xenotransplant in vivo assays; Supplemental Fig.3 gives a description of the purity of CEA used in in vitro assays; Supplemental Fig4 reflects CEA-induced integrin activation and it's independency of VEGF; Supplemental Fig.5 gives a summary of CEAR expression as well as a potential CEA effect in different cell types; Supplemental Fig.6 displays consequences of CEACAM1 downregulation on CEA-induced intracellular signal transduction; a detailed description of the materials and methods used is given in the appendix of the Supplemental Information.
Supplementary Video 1 from A Preclinical Assay for Chemosensitivity in Multiple Myeloma
Authors: Khin Zayar P. , Ribeiro Maria L.C. , Jacobson Timothy , Hazlehurst Lori , Perez Lia , Baz Rachid , Shain Kenneth , Silva Ariosto S.
Published: March 2023

MOV file - 1415K, Patient-derived MM cells (patient 14) were seeded in single (top left) and co-culture with patient-derived stroma cells (top right). They were tested for chemosensitivity to melphalan (continuous exposure for 24h, at highest concentration of 25uM, lowest concentration of 5uM). Digital image analysis algorithm detects live cells and pseudo-colors them as green. MM cells in single culture are significantly more sensitive than in co-culture, a phenomenon commonly referred to as environment-mediated drug resistance (EMDR). At 1nM, bortezomib shows no toxicity to these cells after a 24h continuous exposure (bottom left), but in combination with melphalan, it cancels EMDR (bottom right).
Supplementary Figures 1 - 8 from Monoclonal Antibody Targeting of the Cell Surface Molecule TM4SF5 Inhibits the Growth of Hepatocellular Carcinoma
Authors: Kwon Sanghoon , Choi Kyung-Chan , Kim Young-Eun , Ha Yang-Wha , Kim Dongbum , Park Byoung Kwon , Wu Guang , Kim Doo-Sik , Lee Younghee , Kwon Hyung-Joo
Published: March 2023

PDF file - 1470KB, Supplementary Figure S1. Purification and reactivity analysis of anti-TM4SF5 monoclonal antibody. Supplementary Figure S2. Specificity of anti-TM4SF5 monoclonal antibody. Supplementary Figure S3. Investigation of TM4SF5 expression in normal tissues. Supplementary Figure S4. Expression of TM4SF5 in HCC tissues. Supplementary Figure S5. Analysis of TM4SF5 expression in various cancer tissues. Supplementary Figure S6. Effects of the anti-TM4SF5 monoclonal antibody on E-cadherin expression. Supplementary Figure S7. Effects of the anti-TM4SF5 monoclonal antibody on actin organization. Supplementary Figure S8. Time-dependent biodistribution of the anti-TM4SF5 monoclonal antibody in HCC tumor tissue.
Supplementary Figure 1 from Redox Modulation of Adjacent Thiols in VLA-4 by AS101 Converts Myeloid Leukemia Cells from a Drug-Resistant to Drug-Sensitive State
Authors: Layani-Bazar Adi , Skornick Itai , Berrebi Alain , Pauker Maor H. , Noy Elad , Silberman Alon , Albeck Michael , Longo Dan L. , Kalechman Yona , Sredni Benjamin
Published: March 2023

PDF file - 1027K, Fig. S1: AS101 induces chemotherapy-induced apoptotic death by decreasing VLA-4 activity.
Supplementary Figure 4 from De Novo Design of a Tumor-Penetrating Peptide
Authors: Alberici Luca , Roth Lise , Sugahara Kazuki N. , Agemy Lilach , Kotamraju Venkata R. , Teesalu Tambet , Bordignon Claudio , Traversari Catia , Rizzardi Gian-Paolo , Ruoslahti Erkki
Published: March 2023

PDF file - 1MB, iNGR is cleaved upon entering the cells
Supplementary Figures 1 - 11 from Prodigiosin Rescues Deficient p53 Signaling and Antitumor Effects via Upregulating p73 and Disrupting Its Interaction with Mutant p53
Authors: Hong Bo , Prabhu Varun V. , Zhang Shengliang , van den Heuvel A. Pieter J. , Dicker David T. , Kopelovich Levy , El-Deiry Wafik S.
Published: March 2023

PDF file - 703K, The induction of p21 by prodigiosin at earlier time point (4 hr) in HOP92 cells (S1); Prodigiosin and compound R induce cell cycle arrest at early time point (S2); Prodigiosin does not induce γH2AX foci formation (S3); The higher concentration (1 μM) of prodigiosin or compound R induces cellular apoptosis at 72 hr treatment in HFF normal cells (S4); Dose-responsive curve of prodigiosin in HFF normal cells and SW480 cancer (S5); The effect of prodigiosin on the p53 pathway in normal cells (S6); The effect of prodigiosin on mutant p53 in SW480 cells, and the effect of prodigiosin on wild type p53, p73 and their target proteins in HCT116 cells (S7); The effect of prodigiosin on p63 in SW480 and HCT116 p53-/- cells (S8); High concentration (100 nM) of rapamycin does not disrupt the interaction of mutant p53 and p73 (S9); The bar graph indicates the quantitative data for Ki67 and TUNEL staining (S10); Body weight of nude mice following 5 mg/kg prodigiosin or DMSO treatment in HT29 xenografts and SW480 xenografts (S11).
Supplementary Figure 5 from Increased Dietary Vitamin D Suppresses MAPK Signaling, Colitis, and Colon Cancer
Authors: Meeker Stacey , Seamons Audrey , Paik Jisun , Treuting Piper M. , Brabb Thea , Grady William M. , Maggio-Price Lillian
Published: March 2023

PDF file - 14K, High dietary vitamin D decreases p-P38 and p-P65 expression.
Supplementary Figure S4 from LIMD2 Is a Small LIM-Only Protein Overexpressed in Metastatic Lesions That Regulates Cell Motility and Tumor Progression by Directly Binding to and Activating the Integrin-Linked Kinase
Authors: Peng Hongzhuang , Talebzadeh-Farrooji Mehdi , Osborne Michael J. , Prokop Jeremy W. , McDonald Paul C. , Karar Jayashree , Hou Zhaoyuan , He Mei , Kebebew Electron , Orntoft Torben , Herlyn Meenhard , Caton Andrew J. , Fredericks William , Malkowicz Bruce , Paterno Christopher S. , Carolin Alexandra S. , Speicher David W. , Skordalakes Emmanuel , Huang Qihong , Dedhar Shoukat , Borden Katherine L.B. , Rauscher Frank J.
Published: March 2023

The cell surface area was measured for breast cancer cell lines MDAMB231 (parental, LIMD2-Si5, restoration with vector and LIMD2) using Image-Pro Plus 7.0 program.
Supplementary Table 1 from Vaccine-Mediated Immunotherapy Directed against a Transcription Factor Driving the Metastatic Process
Authors: Ardiani Andressa , Gameiro Sofia R. , Palena Claudia , Hamilton Duane H. , Kwilas Anna , King Thomas H. , Schlom Jeffrey , Hodge James W.
Published: March 2023

PDF file - 208KB, Recombinant Yeast-Twist vaccination does not induce toxicity.
Supplementary Figure 1 from Loss of Androgen Receptor Expression Promotes a Stem-like Cell Phenotype in Prostate Cancer through STAT3 Signaling
Authors: Schroeder Anne , Herrmann Andreas , Cherryholmes Gregory , Kowolik Claudia , Buettner Ralf , Pal Sumanta , Yu Hua , Müller-Newen Gerhard , Jove Richard
Published: March 2023

PDF file - 1025K, Supplementary Fig. 1: Elevated STAT3 activity results in enhanced tumor growth.
Supplementary Figure 1, Table 1 from Identification of FoxR2 as an Oncogene in Medulloblastoma
Authors: Koso Hideto , Tsuhako Asano , Lyons Eli , Ward Jerrold M. , Rust Alistair G. , Adams David J. , Jenkins Nancy A. , Copeland Neal G. , Watanabe Sumiko
Published: March 2023

PDF file - 574K, Supplementary Figure S1. Expression of GLI1, FOXR2, TGIF2 and ALX4 in human MBs and cancer cell lines. Supplementary Table S1: Primers used in the study.
Supplementary Table 1 from Extracellular Vesicles Modulate the Glioblastoma Microenvironment via a Tumor Suppression Signaling Network Directed by miR-1
Authors: Bronisz Agnieszka , Wang Yan , Nowicki Michal O. , Peruzzi Pierpaolo , Ansari Khairul I. , Ogawa Daisuke , Balaj Leonora , De Rienzo Gianluca , Mineo Marco , Nakano Ichiro , Ostrowski Michael C. , Hochberg Fred , Weissleder Ralph , Lawler Sean E. , Chiocca E. Antonio , Godlewski Jakub
Published: March 2023

PDF file - 282K, SUPPLEMENTARY TABLE 1. List of EV proteins identified by mass spectrometry.
Supplementary Methods from Tumor-Derived GM-CSF Promotes Inflammatory Colon Carcinogenesis via Stimulating Epithelial Release of VEGF
Authors: Wang Yi , Han Gencheng , Wang Ke , Liu Guijun , Wang Renxi , Xiao He , Li Xinying , Hou Chunmei , Shen Beifen , Guo Renfeng , Li Yan , Chen Guojiang
Published: March 2023

PDF file - 154K
Supplementary Figure 3 from Phosphorylation at Ser-181 of Oncogenic KRAS Is Required for Tumor Growth
Authors: Barceló Carles , Paco Noelia , Morell Mireia , Alvarez-Moya Blanca , Bota-Rabassedas Neus , Jaumot Montserrat , Vilardell Felip , Capella Gabriel , Agell Neus
Published: March 2023

PDF file - 646K, Fig. S3. Histological pattern of mice grafts derived from NIH3T3 expressing phosphomutants.
Supplementary Figure 1 from Critical Tumor Suppressor Function Mediated by Epithelial Mig-6 in Endometrial Cancer
Authors: Kim Tae Hoon , Lee Dong-Kee , Cho Sung-Nam , Orvis Grant D. , Behringer Richard R. , Lydon John P. , Ku Bon Jeong , McCampbell Adrienne S. , Broaddus Russell R. , Jeong Jae-Wook
Published: March 2023

PDF file - 250K, Steroid hormone regulation of epithelial Mig-6 in the murine uterus.
Supplementary Methods and Figures Legends from FoxO Transcription Factors Promote AKT Ser473 Phosphorylation and Renal Tumor Growth in Response to Pharmacologic Inhibition of the PI3K–AKT Pathway
Authors: Lin Aifu , Piao Hai-long , Zhuang Li , Sarbassov Dos D. , Ma Li , Gan Boyi
Published: March 2023

PDF file - 91KB
Supplementary Figure Legends from Maintaining Glycogen Synthase Kinase-3 Activity Is Critical for mTOR Kinase Inhibitors to Inhibit Cancer Cell Growth
Authors: Koo Junghui , Yue Ping , Gal Anthony A. , Khuri Fadlo R. , Sun Shi-Yong
Published: March 2023

PDF file - 53KB
Supplementary Table 1 from Cysteine Catabolism: A Novel Metabolic Pathway Contributing to Glioblastoma Growth
Authors: Prabhu Antony , Sarcar Bhaswati , Kahali Soumen , Yuan Zhigang , Johnson Joseph J. , Adam Klaus-Peter , Kensicki Elizabeth , Chinnaiyan Prakash
Published: March 2023

PDF file - 53K, Top ten metabolites with highest fold increases (red) and decreases (green) in GBM when compared to Grade II glioma.
Supplementary Figure 7 from Cysteine Catabolism: A Novel Metabolic Pathway Contributing to Glioblastoma Growth
Authors: Prabhu Antony , Sarcar Bhaswati , Kahali Soumen , Yuan Zhigang , Johnson Joseph J. , Adam Klaus-Peter , Kensicki Elizabeth , Chinnaiyan Prakash
Published: March 2023

PDF file - 99K, (A) CDO1 expression in normal brain and glioblastoma evaluated on the TCGA database. (B) CDO1 expression in normal brain sections using IHC.
Supplementary Figure 2 from Maintaining Glycogen Synthase Kinase-3 Activity Is Critical for mTOR Kinase Inhibitors to Inhibit Cancer Cell Growth
Authors: Koo Junghui , Yue Ping , Gal Anthony A. , Khuri Fadlo R. , Sun Shi-Yong
Published: March 2023

PDF file - 142KB, Effects of SB216763 and INK128 combination on mouse body weights.
Supplementary Figure 4 from Cysteine Catabolism: A Novel Metabolic Pathway Contributing to Glioblastoma Growth
Authors: Prabhu Antony , Sarcar Bhaswati , Kahali Soumen , Yuan Zhigang , Johnson Joseph J. , Adam Klaus-Peter , Kensicki Elizabeth , Chinnaiyan Prakash
Published: March 2023

PDF file - 34K, CDO1 expression in GBM cell lines.
Supplementary Figures S1-2, Tables 1-2 from Small-Molecule NSC59984 Restores p53 Pathway Signaling and Antitumor Effects against Colorectal Cancer via p73 Activation and Degradation of Mutant p53
Authors: Zhang Shengliang , Zhou Lanlan , Hong Bo , van den Heuvel A. Pieter J. , Prabhu Varun V. , Warfel Noel A. , Kline Christina Leah B. , Dicker David T. , Kopelovich Levy , El-Deiry Wafik S.
Published: March 2023

Supplementary Figures S1-2, Tables 1-2 Supplementary figure S1. Cell cycle profiles of cancer cells at 8 hours after NSC59984 treatment. Supplementary Figure S2. Effect of NSC59984 treatment on the conformation of mutant p53 in cancer cells. Supplementary Table 1. Combination indices for the NSC59984 treatment with Ad-p73 on cell viability in DLD-1 cells. Supplementary Table 2. Combination indices for the NSC59984 and CPT-11 treatment on cell viability in cells.
Supplementary Figures 1 - 5 from IRP2 Regulates Breast Tumor Growth
Authors: Wang Wei , Deng Zhiyong , Hatcher Heather , Miller Lance D. , Di Xiumin , Tesfay Lia , Sui Guangchao , D'Agostino Ralph B. , Torti Frank M. , Torti Suzy V.
Published: March 2023

PDF file - 514K, Supplemental Figures 1-5. Supplemental Fig 1: IRP2, TfR1 and Ferritin H transcript levels in a series of breast cancer cell lines examined by real-time qPCR. Supplemental Fig 2. IRP2, TfR1 and Ferritin H transcript levels in IRP2 knockdown MDA-MB-231 cells. Supplemental Fig 3. Growth of MCF7 cells following IRP2 knockdown. Supplemental Fig 4. IRP2 overexpression is not sufficient to increase proliferation of MCF10A cells. Supplemental Fig 5. Bioluminescent images of tumor xenografts on day 32.
Supplementary Table 1 from YAP-Induced Resistance of Cancer Cells to Antitubulin Drugs Is Modulated by a Hippo-Independent Pathway
Authors: Zhao Yulei , Khanal Prem , Savage Paul , She Yi-Min , Cyr Terry D. , Yang Xiaolong
Published: March 2023

PDF file - 139KB, Drugs and protein kinase inhibitors used in this study.
Supplementary Figure 4 from YAP-Induced Resistance of Cancer Cells to Antitubulin Drugs Is Modulated by a Hippo-Independent Pathway
Authors: Zhao Yulei , Khanal Prem , Savage Paul , She Yi-Min , Cyr Terry D. , Yang Xiaolong
Published: March 2023

PDF file - 547KB, Response of MCF10A cells expressing wild-type and mutant YAP to Cisplatin.
Supplementary Figure 1 from YAP-Induced Resistance of Cancer Cells to Antitubulin Drugs Is Modulated by a Hippo-Independent Pathway
Authors: Zhao Yulei , Khanal Prem , Savage Paul , She Yi-Min , Cyr Terry D. , Yang Xiaolong
Published: March 2023

PDF file - 5684KB, Identification of 4 phosphorylation sites in YAP by mass spectrometry.
Supplementary Figure 4 from NUP98 Fusion Oncoproteins Promote Aneuploidy by Attenuating the Mitotic Spindle Checkpoint
Authors: Salsi Valentina , Ferrari Silvia , Gorello Paolo , Fantini Sebastian , Chiavolelli Francesca , Mecucci Cristina , Zappavigna Vincenzo
Published: March 2023

PDF - 1659K, Supplementary Figure 4. siRNA knock-down experiments. A, Immunoblots showing the effects of siRNAs on CDC20 or CDH1 protein expression. Anti-betaactin was used as a loading control. Graphs representing immunoblot quantitations are shown on the right side. B, Cell cycle analysis using propidium iodide staining and flow citometry on control siRNA-treated HEK293 cells (left side), and on siRNA-treated HEK293 cells expressing the NUP98-HOXD13 oncogene (right side).
Supplementary Figure S2 from Distinct Functions of Epidermal and Myeloid-Derived VEGF-A in Skin Tumorigenesis Mediated by HPV8
Authors: Ding Xiaolei , Lucas Tina , Marcuzzi Gian P. , Pfister Herbert , Eming Sabine A.
Published: March 2023

Supplementary Figure S2. Blocking VEGFR2 shows no impact on epidermal keratinocyte proliferation and apoptosis.
Data Supplement from Heparanase Cooperates with Ras to Drive Breast and Skin Tumorigenesis
Authors: Boyango Ilanit , Barash Uri , Naroditsky Inna , Li Jin-Ping , Hammond Edward , Ilan Neta , Vlodavsky Israel
Published: March 2023

Supplementary Figure 1:Three dimensional model of heparanase and over-expression of heparanase and the heparanase C-terminal domain (8C) in MCF10A cells.
Data Supplement from Heparanase Cooperates with Ras to Drive Breast and Skin Tumorigenesis
Authors: Boyango Ilanit , Barash Uri , Naroditsky Inna , Li Jin-Ping , Hammond Edward , Ilan Neta , Vlodavsky Israel
Published: March 2023

Supplementary Figure 3:Subcutaneous implantation of MCF10AT1 cells.
Data Supplement from Intestinal Epithelial HuR Modulates Distinct Pathways of Proliferation and Apoptosis and Attenuates Small Intestinal and Colonic Tumor Development
Authors: Giammanco Antonina , Blanc Valerie , Montenegro Grace , Klos Coen , Xie Yan , Kennedy Susan , Luo Jianyang , Chang Sung-Hee , Hla Timothy , Nalbantoglu ILKe , Dharmarajan Sekhar , Davidson Nicholas O.
Published: March 2023

Legend for Supplemental Figures S1-S3.
Supplementary Table S4 from TGFβ Receptor 1: An Immune Susceptibility Gene in HPV-Associated Cancer
Authors: Levovitz Chaya , Chen Dan , Ivansson Emma , Gyllensten Ulf , Finnigan John P. , Alshawish Sara , Zhang Weijia , Schadt Eric E. , Posner Marshal R. , Genden Eric M. , Boffetta Paolo , Sikora Andrew G.
Published: March 2023

Supplementary Table S4. PPI analysis p-values determined using DAPPLE
Supplementary Table S1 from Myostatin Gene Inactivation Prevents Skeletal Muscle Wasting in Cancer
Authors: Gallot Yann S. , Durieux Anne-Cécile , Castells Josiane , Desgeorges Marine M. , Vernus Barbara , Plantureux Léa , Rémond Didier , Jahnke Vanessa E. , Lefai Etienne , Dardevet Dominique , Nemoz Georges , Schaeffer Laurent , Bonnieu Anne , Freyssenet Damien G.
Published: March 2023

Oligonucleotide primers used for qPCR analysis.
Data Supplement from Pyrvinium Attenuates Hedgehog Signaling Downstream of Smoothened
Authors: Li Bin , Fei Dennis Liang , Flaveny Colin A. , Dahmane Nadia , Baubet Valérie , Wang Zhiqiang , Bai Feng , Pei Xin-Hai , Rodriguez-Blanco Jezabel , Hang Brian , Orton Darren , Han Lu , Wang Baolin , Capobianco Anthony J. , Lee Ethan , Robbins David J.
Published: March 2023

Pyrvinium attenuates SHH signaling via CK1a (Figure S1); Validation of CK1a shRNA (Figure S2); Increased CK1a activity induces Gli1 degradation (Figure S3).
Data Supplement from IL4 Receptor ILR4α Regulates Metastatic Colonization by Mammary Tumors through Multiple Signaling Pathways
Authors: Venmar Katherine T. , Carter Kathy J. , Hwang Daniel G. , Dozier E. Ashley , Fingleton Barbara
Published: March 2023

Supplemental Figure 7: Reduced IL4Ra expression results in reduced Erk and Akt activation in lung metastases
Data Supplement from Afatinib Enhances the Efficacy of Conventional Chemotherapeutic Agents by Eradicating Cancer Stem–like Cells
Authors: Wang Xiao-kun , He Jie-hua , Xu Jing-hong , Ye Sheng , Wang Fang , Zhang Hui , Huang Zhen-cong , To Kenneth Kin Wah , Fu Li-wu
Published: March 2023

Supplementary methods
Supplementary Figure S1 from Selective In Vivo Imaging of Syngeneic, Spontaneous, and Xenograft Tumors Using a Novel Tumor Cell–Specific Hsp70 Peptide-Based Probe
Authors: Stangl Stefan , Varga Julia , Freysoldt Bianca , Trajkovic-Arsic Marija , Siveke Jens T. , Greten Florian R. , Ntziachristos Vasilis , Multhoff Gabriele
Published: March 2023

Supplemental Figure S1: Specificity of TPP to Hsp70 vs Hsp60 protein
Supplementary Figure 2 from RAGE Expression in Tumor-Associated Macrophages Promotes Angiogenesis in Glioma
Authors: Chen Xuebo , Zhang Leying , Zhang Ian Y. , Liang Junling , Wang Huaqing , Ouyang Mao , Wu Shihua , da Fonseca Anna Carolina Carvalho , Weng Lihong , Yamamoto Yasuhiko , Yamamoto Hiroshi , Natarajan Rama , Badie Behnam
Published: March 2023

Supplementary Fig. 2: RAGE ablation in GL261 gliomas results in the formation of dilated, leaky vessels.
Supplementary Figure 1 from RAGE Expression in Tumor-Associated Macrophages Promotes Angiogenesis in Glioma
Authors: Chen Xuebo , Zhang Leying , Zhang Ian Y. , Liang Junling , Wang Huaqing , Ouyang Mao , Wu Shihua , da Fonseca Anna Carolina Carvalho , Weng Lihong , Yamamoto Yasuhiko , Yamamoto Hiroshi , Natarajan Rama , Badie Behnam
Published: March 2023

Supplementary Fig. 1: Expression of RAGE in the GL261 glioma blood vessels (CD31+).
Supplementary Figure 4 from A Regulatory Loop Involving miR-22, Sp1, and c-Myc Modulates CD147 Expression in Breast Cancer Invasion and Metastasis
Authors: Kong Ling-Min , Liao Cheng-Gong , Zhang Yang , Xu Jing , Li Yu , Huang Wan , Zhang Yi , Bian Huijie , Chen Zhi-Nan
Published: March 2023

PDF file - 61K, Luciferase assays the effect of miR-22 on Sp3 and Sp4 post-transcriptional regulation.
Supplementary Figures 1 - 9 from The Cancer Stem Cell Marker Aldehyde Dehydrogenase Is Required to Maintain a Drug-Tolerant Tumor Cell Subpopulation
Authors: Raha Debasish , Wilson Timothy R. , Peng Jing , Peterson David , Yue Peng , Evangelista Marie , Wilson Catherine , Merchant Mark , Settleman Jeff
Published: March 2023

PDF file - 1635KB, Elevated ALDH1A1 activity in KATO II and GTL-16 DTPs (S1). ALDHhigh cells exhibit properties similar to CSCs (S2). Effect of DS on growth of parental cells and DTPs (S3). DS has opposite effects on pre- and post- KI-treated cells (S4). ALDH family members are expressed at higher level in DTPs (S5). Role of specific ALDH isoforms and cell density in drug tolerance drug (S6). Effect of the alternative ALDH inhibitor gossypol on drug-tolerant cells (S7). Increased mitochondrial respiration and ROS levels in KATO II ALDHhigh cells (S8). DS effect is not mediated by inhibition of efflux pumps or through proteasome inhibition (S9).
Data Supplement from Molecular Homology and Difference between Spontaneous Canine Mammary Cancer and Human Breast Cancer
Authors: Liu Deli , Xiong Huan , Ellis Angela E. , Northrup Nicole C. , Rodriguez Carlos O. , O'Regan Ruth M. , Dalton Stephen , Zhao Shaying
Published: March 2023

Supplementary Table S5. Supplementary data indicating no differences in histone modification intensity between luminal epithelial cells and myoepithelial cells in complex carcinomas.
Supplementary Table 2 from Gene Profiling of Canine B-Cell Lymphoma Reveals Germinal Center and Postgerminal Center Subtypes with Different Survival Times, Modeling Human DLBCL
Authors: Richards Kristy L. , Motsinger-Reif Alison A. , Chen Hsiao-Wei , Fedoriw Yuri , Fan Cheng , Nielsen Dahlia M. , Small George W. , Thomas Rachael , Smith Chris , Dave Sandeep S. , Perou Charles M. , Breen Matthew , Borst Luke B. , Suter Steven E.
Published: March 2023

XLSX file - 40K, Canine genes identified by Ingenuity Pathway Analysis as part of the NF-kB or B-cell receptor signaling pathways (Fig. 5).
Data Supplement from Molecular Homology and Difference between Spontaneous Canine Mammary Cancer and Human Breast Cancer
Authors: Liu Deli , Xiong Huan , Ellis Angela E. , Northrup Nicole C. , Rodriguez Carlos O. , O'Regan Ruth M. , Dalton Stephen , Zhao Shaying
Published: March 2023

Supplementary Table S6. Supplementary data for differentially expressed genes between canine ER+ and ER- carcinomas, including the gene list and enriched functions among the genes.
Supplementary Table 1 from Gene Profiling of Canine B-Cell Lymphoma Reveals Germinal Center and Postgerminal Center Subtypes with Different Survival Times, Modeling Human DLBCL
Authors: Richards Kristy L. , Motsinger-Reif Alison A. , Chen Hsiao-Wei , Fedoriw Yuri , Fan Cheng , Nielsen Dahlia M. , Small George W. , Thomas Rachael , Smith Chris , Dave Sandeep S. , Perou Charles M. , Breen Matthew , Borst Luke B. , Suter Steven E.
Published: March 2023

XLSX file - 116K, Canine genes that distinguish "ABC-like" and "GCB-like" subtypes (Fig. 5).
Data Supplement from Molecular Homology and Difference between Spontaneous Canine Mammary Cancer and Human Breast Cancer
Authors: Liu Deli , Xiong Huan , Ellis Angela E. , Northrup Nicole C. , Rodriguez Carlos O. , O'Regan Ruth M. , Dalton Stephen , Zhao Shaying
Published: March 2023

Supplementary Table S7. Supplementary data indicating altered genes and their function information.
Supplementary Tables 1 - 6 from Say No to DMSO: Dimethylsulfoxide Inactivates Cisplatin, Carboplatin, and Other Platinum Complexes
Authors: Hall Matthew D. , Telma Katherine A. , Chang Ki-Eun , Lee Tobie D. , Madigan James P. , Lloyd John R. , Goldlust Ian S. , Hoeschele James D. , Gottesman Michael M.
Published: March 2023

XLS file - 106KB, Use of solvent for assessing cytotoxicity of platinum complexes in the journal Molecular Cancer Therapeutics (S1). Use of solvent for assessing cytotoxicity of platinum complexes in the journal Public Library of Science (PLoS)(S2). Use of solvent for assessing cytotoxicity of platinum complexes in the journal Journal of Pharmacology and Experimental Therapeutics (JPET) (S3). Use of solvent for assessing cytotoxicity of platinum complexes in the journal Cancer Research (S4). Use of solvent for assessing cytotoxicity of platinum complexes in the journal Molecular Pharmacology (S5). Use of solvent for assessing cytotoxicity of platinum complexes (S6).
Supplementary Figure 1 from Say No to DMSO: Dimethylsulfoxide Inactivates Cisplatin, Carboplatin, and Other Platinum Complexes
Authors: Hall Matthew D. , Telma Katherine A. , Chang Ki-Eun , Lee Tobie D. , Madigan James P. , Lloyd John R. , Goldlust Ian S. , Hoeschele James D. , Gottesman Michael M.
Published: March 2023

PDF file - 1000KB, Scheme demonstrating the aquation of cisplatin in water, and prevention when stabilized in high chloride solution.
Supplementary Figure Legends from Sentinel Lymph Node Biopsy Revisited: Ultrasound-Guided Photoacoustic Detection of Micrometastases Using Molecularly Targeted Plasmonic Nanosensors
Authors: Luke Geoffrey P. , Myers Jeffrey N. , Emelianov Stanislav Y. , Sokolov Konstantin V.
Published: March 2023

Legend for Supplementary Figures S1-S2.
Supplementary Figure 3 from Patient-Derived Ovarian Tumor Xenografts Recapitulate Human Clinicopathology and Genetic Alterations
Authors: Ricci Francesca , Bizzaro Francesca , Cesca Marta , Guffanti Federica , Ganzinelli Monica , Decio Alessandra , Ghilardi Carmen , Perego Patrizia , Fruscio Robert , Buda Alessandro , Milani Rodolfo , Ostano Paola , Chiorino Giovanna , Bani Maria Rosa , Damia Giovanna , Giavazzi Raffaella
Published: March 2023

Supplementary Figure 3. Comparative immunohistochemical analysis of xenografts at different passages.
Supplementary Fig. 3 from Metastasis Stimulation by Hypoxia and Acidosis-Induced Extracellular Lipid Uptake Is Mediated by Proteoglycan-Dependent Endocytosis
Authors: Menard Julien A. , Christianson Helena C. , Kucharzewska Paulina , Bourseau-Guilmain Erika , Svensson Katrin J. , Lindqvist Eva , Chandran Vineesh Indira , Kjellén Lena , Welinder Charlotte , Bengzon Johan , Johansson Maria C. , Belting Mattias
Published: March 2023

Figure S3. A,B, Increased lipoprotein uptake by hypoxia in several cell types. C, Temperature-dependent uptake of lipoproteins. D, Competitive inhibition of DiI-labelled lipoprotein uptake. E and F, Hypoxia does not induce macropinocytosis.
Supplementary Figures S1-S4 from Modeling Lung Cancer Evolution and Preclinical Response by Orthotopic Mouse Allografts
Authors: Ambrogio Chiara , Carmona Francisco J. , Vidal August , Falcone Mattia , Nieto Patricia , Romero Octavio A. , Puertas Sara , Vizoso Miguel , Nadal Ernest , Poggio Teresa , Sánchez-Céspedes Montserrat , Esteller Manel , Mulero Francisca , Voena Claudia , Chiarle Roberto , Barbacid Mariano , Santamaría David , Villanueva Alberto
Published: March 2023

Supplementary Figures S1-S4. Common histological subtypes of NSCLC orthoallografts (S1); In vitro characterization of primary cell lines derived from NSCLC orthoallografts (S2); Lung colonization and tumor formation upon reintroduction of mKLC cell lines (S3); Inoculation of mKLC single cell clones gives rise to NSCLC heterogeneity in vivo (S4).
Supplementary methods, figure legends and references from Activated d16HER2 Homodimers and SRC Kinase Mediate Optimal Efficacy for Trastuzumab
Authors: Castagnoli Lorenzo , Iezzi Manuela , Ghedini Gaia C. , Ciravolo Valentina , Marzano Giulia , Lamolinara Alessia , Zappasodi Roberta , Gasparini Patrizia , Campiglio Manuela , Amici Augusto , Chiodoni Claudia , Palladini Arianna , Lollini Pier Luigi , Triulzi Tiziana , Menard Sylvie , Nanni Patrizia , Tagliabue Elda , Pupa Serenella M.
Published: March 2023

Supplementary methods, figure legends and references