bluuebunny/crossref_metadata_2025 huggingface dataset:
Pharmacist Goes to School: Promoting DAGUSIBU As A Pharmaceutical Education Tool for Adolescents
Authors: Saputra Yoga Dwi , Ulya Tuhfatul , Hasina Raisya , Aini Siti Rahmatul , Puspitasari Candra Eka , Andanalusia Mahacita , Lisnasari Baiq Risky Wahyu , Hamdin Candra Dwipayana
Published: December 2024

Drug misuse is an urgent public health issue, often arising from a lack of knowledge about proper medication use. Research shows that over half of the medications worldwide are used irrationally. The DAGUSIBU program (Dapatkan, Gunakan, Simpan, Buang or known as Get, Use, Store, Dispose) was developed as a solution to address this issue by providing education on proper medication management. This community service activity was organized by the Pharmacy Study Program and the Pharmacy Professional Education Program (PSPPA), Faculty of Medicine and Health Sciences (FKIK), Universitas Mataram, on August 9, 2024, at Kesuma Catholic High School in Mataram. The primary goal of this activity was to teach students the correct ways to obtain, use, store, and dispose of medications, as well as to introduce the pharmacist profession and the Pharmacy program at UNRAM to high school students. The activity included interactive presentations on DAGUSIBU, an introduction to the pharmacist profession, and a quiz competition as an evaluation method. The quiz encouraged active student participation, with prizes to boost motivation. Despite challenges such as varying levels of student comprehension and time constraints, the activity successfully improved students’ understanding of rational drug use and introduced career opportunities in pharmacy. Overall, this activity proved effective in raising student awareness and knowledge, positively impacting their health literacy.
Implementasi Horisontal Net Untuk Meningkatkan Peran Perempuan Dalam Pengelolaan Kebun Bibit Rumput Laut
Authors: Kasim Ma'ruf , Sudia LaBaco , Nurdiana Nurdiana , Jalil Wardha
Published: December 2024

Seaweed cultivation currently uses the longline method. In practice, the longline method demands significant effort, leading to a greater male dominance in the cultivation process. This community service activity offers the most effective approach to enhancing the involvement of women in seaweed cultivation. We carried out this community service activity in one of the cultivation areas in North Buton Regency, Southeast Sulawesi Province. Seaweed farmers received training and assistance to implement horizontal nets. Twenty female seaweed farmers and 20 male farmers participated in the training. During the training activities, women play a significant role by performing practical tasks such as creating, cultivating, and maintaining horizontal net tools used in seaweed cultivation. At the field implementation level, women play a greater role in operating and maintaining horizontal nets. This community service activity has instilled new hope in expanding the availability of seaweed seed gardens and enhancing the role of women, thereby potentially increasing the income of female seaweed farmers.
Upaya Peningkatan Produktivitas Petani Tembakau Melalui Diversifikasi Budidaya Sayur-Sayuran di Luar Musim di Desa Mujur Lombok Tengah NTB
Authors: Ngawit I Ketut , Supeno Bambang , Jihadi Amrul
Published: December 2024

Efforts to improve the welfare of tobacco farmers require efforts that focus on increasing income, education, access to technology and information. One way is through diversifying vegetable crops outside the season, to get high prices. The problem is that soil fertility decreases due to water saturation resulting in poor aeration, solid structure and low soil pH. For this reason, counseling and assistance is carried out which aims to increase farmers' knowledge and skills in cultivating vegetable crops outside the season. The participatory action activity method was carried out for 5 months, through several stages, namely, problem identification, implementation, monitoring and evaluation. Counseling and mentoring activities take place in an orderly, safe and smooth manner. Farmers' knowledge and skills have increased, as evidenced by their high participation and enthusiasm in cultivating out-of-season vegetables. The application of agronomic measures such as the use of plastic mulch, organic fertilizer 20 - 25 tons ha-1 and NPK Ponska 75 - 150 kg ha-1, provides higher yields of mustard greens, tomatoes, chilies and shallots compared to the application of NPK Ponska 300 kg ha-1 without organic fertilizer and mulch. The income and profit from cultivating pakchoy, tomatoes, chilies and shallots is more than cultivating spinach, long beans and sweet corn, because the selling value is more expensive and stable with each price, pakchoy Rp. 12,500,- kg-1, tomatoes Rp. 8,500,- kg-1, chilies Rp. 25,000,- kg-1, and shallots Rp. 40,000,- kg-1.
Sumur Resapan sebagai Alternatif Drainase Berwawasan Lingkungan untuk Penanggulangan Genangan Banjir di Desa Suwangi Timur Kabupaten Lombok Timur
Authors: Budianto Muh Bagus , Saidah Humairo , Negara IDG Jaya , Setiawan Ery , Supriyadi Anid
Published: December 2024

East Suwangi Village is one of the villages in Sakra District, has an area of ​​2.17 km2, has hilly geographical conditions and a population of 5,069 people. Based on survey results and interviews with village heads, some areas are prone to flood disasters. The flooding that occurred was caused by overflow from drainage channels, causing it to accumulate on roads and residential areas. One effort to minimize inudation is the implementation of an environmentally friendly drainage system by constructing infiltration wells along flooded channels. The method used in this community service activity is to explain environmentally friendly drainage systems to the community and the practice of making infiltration wells in locations that are often flooded.  The result of this activity is an increase in public understanding of the function and benefits of infiltration wells as a medium for environmentally friendly flood management. And the public can see firsthand how to make infiltration wells through practice in locations that are often flooded.
PEMBERDAYAAN MASYARAKAT DESA SANDIK MELALUI PENGENALAN INSTALASI MODUL SURYA SEBAGAI SUMBER ENERGI LISTRIK DALAM MENDUKUNG PROGRAM DIVERSIFIKASI ENERGI
Authors: Muljono Agung Budi , Nrartha I Made Ari , Ginarsa I Made , Sasongko Sudi Mariyanto Al , Sultan Sultan , Yadnya Made Sutha
Published: December 2024

Kemajuan teknologi di bidang energi, khususnya ketenagalistrikan, diperlukan untuk memanfaatkan sumber energi yang bersih dan terbarukan menuju net zero emisi. Kondisi ini mendukung pemanfaatan energi baru terbarukan (EBT) oleh pemerintah dan masyarakat. Bersama Mitra (kepala desa Sandik) tim Program Pengabdian Karya Dosen Universitas Mataram akan melaksanakan pemberdayaan masyarakat bidang EBT dengan mensosialisasikan Perpres No. 5 tahun 2006 tentang KEN dan PP No. 112 Tahun 2022 tentang Percepatan Pengembangan EBT untuk pasokan penyedia energi listrik serta melakukan pengenalan instalasi modul surya sebagai sumber energi listrik dalam mendukung program diversifikasi energi. Metode yang digunakan adalah presentasi, diskusi, pre-test, post-test, praktek, penggunaan alat ukur energi surya dan presentasi pemasangan modul surya sebagai sumber listrik. Pelaksanaan kegiatan PkM ini dibantu mahasiswa jurusan teknik elektro sistem kelistrikan dan perangkat Desa Sandik. Peserta PkM sebanyak diikuti oleh 21 orang pria dan 9 orang perempuan. Hasil evaluasi prestasi rerata nilai pre-test ke skor post-test meningkat dari 49,725 menjadi 72,0375, rata-rata meningkat sebesar 44,87%. Ketertarikan masyarakat dalam memanfaatkan PLTS sebagai sumber listrik menunjukkan antusiasnya peran serta masyarakat desa Sandik.
PENDAMPINGAN PACKAGING DAN DIGITAL BRANDING PRODUK UMKM MASYARAKAT PESISIR DESA GILI GEDE INDAH
Authors: Ika Wijayanti  , Farida Hilmi  , Latifa Dinar Rahmani Hakim
Published: December 2024

Pengabdian kepada masyarakat yang berjudul Pendampingan Packaging Dan Digital Branding Produk UMKM Masyarakat Pesisir Desa Gili Gede Indah dilaksanakan di Desa Desa Gili Gede, Kecamatan Sekotong Kabupaten Lombok Barat. Gili Gede merupakan jajaran pulau kecil yang memiliki potensi hasil laut dan sebagai daerah tujuan wisatawan. Urgensi dari pengabdian ini adalah dengan melihat minimnya pengetahuan inovasi design produk UMKM yang menarik dan digitalisasi pemasaran. Selain itu, Gili Gede menjadi salah satu destinasi unggulan jajaran kawasan Gili di pesisir barat Lombok yang memiliki produk UMKM pangan berupa olahan hasil bahari dan produk non pangan. Produk UMKM pangan berupa abon ikan tongkol, keripik kerang, dan kerupuk gurita. Permasalahan yang dihadapi oleh UMKM adalah ketersediaan bahan baku yang sangat bergantung pada musim, packaging dan pemasaran. Maka dari kegiatan pengabdian ini perlu dilakukan mengingat peroduk unggulan UMKM Desa Gili Gede menjadi peluang usaha yang membantu ekonomi rumah tangga. Kegiatan akan dimulai dengan FGD (Focus Grup Discussion) untuk mengidentifikasi permasalahan. Kegiatan selanjutnya yaitu pengenalan dan pelatihan aplikasi design untuk packaging. Kegiatan terakhir yaitu pelatihan digital branding produk UMKM.
SOSIALISASI PENERAPAN PEMBELAJARAN BERDEFRENSIASI BERDASARKAN KURIKULUM MERDEKA PADA GURU MGMP PPKn KOTA MATARAM
Authors: Mohammad Ismail  , Mohammad Mustari  , Lalu Sumardi  , Basariah  , Jumrawati
Published: December 2024

Pengabdian Kegiatan pengabdian pada masyarakat ini dilaksanakan berdasarkan kondisi saat ini yang sedang melanda berbagai tempat khususnya di Kota Mataram. Pembelajaran berdiferensiasi menjadi salah satu pilihan yang tepat untuk memenuhi kebutuhan peserta didik dalam memperoleh ilmu dari pendidik. Dalam proses pembelajaran tentunya yang dituntut tidak hanya kemampuan pengetahuan peserta didik, akan tetapi kemampuan sikap dan keterampilan juga harus dapat terpenuhi meskipun melalui pembelajaran daringsebagaimana tujuan dari pembelajaran saat tatap muka langsung. Tujuan pengabdian ini adalah untuk meningkatkan kompetensi para guru di sekolah mitra tentang pembelajaran berdiprensiasi sesuai kurikulum merdeka. Selain itu, guru memiliki konsep pembelajaran yang dapat mencapai tujuan pembelajaran secaraa holistik sehingga hak siswa dapat terpenuhi sebagaimana mestinya. Solusi yang ditawarkan dalam pengabdian ini adalah melakukan serangkaian kegiatan sosialisasi dan pelatihan pembelajaran berdiferensiasi. Kegiatan sosialisasi ini diikuti oleh 20 guru PPKn di Kota Mataram sebagai peserta. Hasil pengabdian menunjukkan bahwa ada peningkatan pengetahuan guru MGMP PPKn SMP Negeri se Kota Mataram. Sebelum kegiatan sebagian besar guru belum begitu memahami terkait pembelajaran berdiferensiasi. Setelah kegiatan, semua memiliki pemahaman baik mengenai hal tersebut dan berkomitmen untuk melakukan pembelajaran berdiferensiasi ke depannya.
A IMPORTÂNCIA DA MOBILIDADE NA PRÁTICA DO FUTEBOL
Authors:   , Quintas Fábio Araújo
Published: December 2024

O Futebol é um esporte que está sempre evoluindo e atualmente não basta o atleta ter apenas boas habilidades individuais, precisa possuir uma boa mobilidade. Esta, por sua vez, é cada vez mais necessária na vida do atleta e pode ser caracterizada como uma valência física da articulação. Quando se tem uma boa mobilidade o atleta pode ter um bom desempenho dentro das quatro linhas desempenhando bons aspectos técnicos como passes, dribles, entre outros, posicionamentos, defesa eficiente, movimentos dinâmicos e complexos, aspectos táticos, adaptação ao estilo de jogo e um dos mais importantes, a prevenção de lesões. A Flexibilidade também faz parte de todo este contexto, pois ambos trabalham em sinergia, porém, caso haja algum desequilíbrio entre ambos, isto pode ocasionar alguma possível lesão ou um mal desempenho do atleta em campo, pensando por este lado, o estudo abaixo foi elaborado como forma de apresentar a importância de se praticar a mobilidade dentro do futebol. Como amostra, foi realizado uma pesquisa de campo para avaliar como estava o nível de flexibilidade e mobilidade de algumas articulações de cada um dos 30 atletas avaliados, focando em membros inferiores e superiores, foi possível identificar que muitos atletas de categorias diferentes possuem diferenças bem significativas ao medir a angulação de cada um, e as causas podem ser diversas como, desvios posturais, falta de práticas de atividades físicas, comodismo, sedentarismo, ou ainda alguma possível lesão.
GEODIVERSIDADE DE PERNAMBUCO: CARACTERÍSTICAS PEDOLÓGICAS
Authors: Araújo Filho José Coelho de , Marques Flávio Adriano , Araújo Maria do Socorro Bezerra de , Sampaio Everardo Valadares de Sá Barreto
Published: December 2024

O capítulo cinco apresenta os solos de Pernambuco levando em consideração os aspectos da geodiversidade. A diversidade dos tipos de rocha favorece o desenvolvimento de uma gama de solos, controlados por topografia, clima e outros fatores.
CLIMAS DE PERNAMBUCO
Authors: Nóbrega Ranyére Silva , Anjos Rafael Silva dos , Soares Deivide Benicio , Wanderley Lucas Suassuna de Albuquerque
Published: December 2024

O capítulo seis trata da variação climática do estado de Pernambuco nas suas distintas regiões geográficas. As características topográficas do estado com os seus brejos de altitude são apresentadas, junto com as preocupações concernentes a eventos extremos, que carecem de monitoramento.
GEODIVERSIDADE DE PERNAMBUCO: CARACTERÍSTICAS MINERAIS
Authors: Souza Sebastião Rodrigo Cortez de , Noronha Daniel Delduque de , Souza Neto João Adauto
Published: December 2024

O capítulo sete apresenta e discute os recursos minerais de Pernambuco passando por minerais metálicos e não metálicos e suas contribuições para o desenvolvimento social e econômico do Estado. Apresenta uma visão atual da mineração em Pernambuco, sua importância e as potencialidades futuras.
Linguagem jurídica: produção textual, direito e argumentação v.3
Authors: Oliveira Ana Larissa Adorno Marciotto , Dias Luiz Francisco , Santos Isabel Peixoto dos
Published: December 2024

Em seu volume 3, esta coletânea congrega artigos provenientes de trabalhos de conclusão de curso da turma 2023/1, terceira turma do Curso de Especialização em Linguagem Jurídica (LINJUR) da Faculdade de Letras da Universidade Federal de Minas Gerais. Ao representar uma conquista acadêmica importante para os autores, a obra também procura modestamente cumprir a função de aproximar a comunidade ao trabalho produzido no curso. Ela também busca servir de encorajamento aos alunos concluintes para que continuem a perseguir o aperfeiçoamento profissional e acadêmico, sempre desejáveis e cada vez mais necessários, principalmente frente às rápidas mudanças dos tempos presentes.
COMBATE À DESINFORMAÇÃO NO PROCESSO ELEITORAL BRASILEIRO: ANÁLISE DA RESOLUÇÃO N.º 23.714, DE 2022
Authors: Pereira Júnior Antônio Afonso , Cabra Ana Lúcia Tinoco
Published: December 2024

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REFLEXÃO CRÍTICA COMO UM JUIZ OU JURISTA NEGRO SOBRE DECISÕES JUDICIAIS CONTRÁRIAS ÀS DECISÕES DAS BANCAS DE HETEROIDENTIFICAÇÃO – NECESSIDADE DE RETEXTUALIZAÇÃO/REESCRITA
Authors: Santos Grigório Carlos dos , Cabral Ana Lúcia Tinoco
Published: December 2024

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UMA ANÁLISE HERMENÊUTICA DO ART. 142 CRFB/88: A INTERPRETAÇÃO DA ANÁLISE DO DISCURSO DOS ATORES PÚBLICOS E A SEMIÓTICA DO PODER
Authors: Brito Marco Aurélio de , Oliveira Ana Larissa Adorno Marciotto
Published: December 2024

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TERMOS TÉCNICOS JURÍDICOS E A IMPRENSA BRASILEIRA: INCORREÇÕES NA ADAPTAÇÃO DA LINGUAGEM JURÍDICA NO JORNAL O TEMPO
Authors: Reis Vinícius Fernandes , Oliveira Fabiana Meireles de
Published: December 2024

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Non-invasive exosome diagnostics for Parkinson's disease
Authors: Alejandro Mella-Diaz  , Diana L Escobedo-Andrade  , Oscar J Fierro-Cisneros  , Victor Valdez-Hernández  , Jorge Felix-Mendivil  , Andrik S Alcalá-Nevárez  , Brissia Lazalde
Published: December 2024

Parkinson's disease (PD) is a neurodegenerative disease, characterized by signs and symptoms such as festinating gait, bradykinesia, resting tremor, and cognitive delays.
Exosomes have emerged as biomarkers of clinical interest for the diagnosis and prevention of Parkinson's disease. These organelles between 30 nm and 200 nm in diameter play a crucial role in protein biogenesis, cellular homeostasis, and cell-to-cell signal transmission.
Exosomes with intraneuronal accumulation of α-synuclein protein are relevant in Parkinson's disease as a key pathological feature in disease progression and Lewy body formation.
A review on recent advancement and pharmacological management of migraine
Authors: Sharda K. Lokade  , Ashish N. Umale  , Swati P. Deshmukh  , Neha. R.Jadhav  , Prajwal P. Raghuwanshi  , Arun V. Kamble
Published: December 2024

Modern theories suggest that the primary disorder in migraine takes place within the CNS and that this inspires adjustments in blood vessels within pain-producing intracranial meningeal systems that deliver upward push to headache pain. Migraine is now concept of as a neurovascular ailment it has been proposed that genetic abnormalities may be answerable for changing the response threshold to migraine particular trigger elements in the mind of a migraine compared to a normal individual. the exact nature of the principal disorder that is produced in migraine continues to be not clear and can contain spreading despair-like phenomena and activation of mind stem monoaminergic nuclei that are a part of the primary autonomic, vascular and ache control facilities. it is commonly notion that local vasodilatation of intracranial extracerebral blood vessels and a consequent stimulation of surrounding trigeminal sensory nervous ache pathways is a key mechanism underlying the era of headache ache related to migraine. This activation of the Trigeminovascular device’ is idea to reason the release of vasoactive sensory neuropeptides, mainly CGRP, that boom the ache reaction. The activated trigeminal nerves deliver nociceptive records to significant neurons within the mind stem trigeminal sensory nuclei that in turn relay the ache alerts to better facilities in which headache pain is perceived. it's been hypothesized that these significant neurons may become sensitized as a migraine assault progresses.The ‘triptan’ anti-migraine marketers (e.g. sumatriptan, rizatriptan, zolmitriptan naratriptan) are serotonergic agonists which have been proven to act selectively via inflicting vasoconstriction through 5-HT1B receptors which are expressed in human intracranial arteries and by way of inhibiting nociceptive transmission via an movement at five-HT1D receptors on peripheral trigeminal sensory nerve terminals within the meninges and crucial terminals in brain stem sensory nuclei. these 3 complementary web sites of movement underlie the clinical effectiveness of the 5-HT1B/1D agonists towards migraine headache pain and its related signs and symptoms
Kinetic Studies on the Inhibition Potential of Bitter Leaf (Vernonia Amygdalin) in the Management of Diabetes
Authors: Uthman H
Published: December 2024

The aim of this study was to investigate the inhibition potential of extracts from Vernonia amygdalina on α-amylase and α-glucosidase activity, and its useful mechanisms in the treatment of diabetes specifically Type 2. The searchlight is beamed on the potential of the plant extract to inhibit the activity of α-amylase and thereby determining its mechanism or mode on inhibition as well as its IC50 value. The inhibition of alpha-amylase and alpha-glucosidase enzymes is a key strategy in managing diabetes. Vernonia amygdalina is a natural plant extract that has been used traditionally to manage diabetes. In this study, the inhibition potential of Vernonia amygdalina on alpha-amylase and alpha-glucosidase was investigated. Kinetic studies were conducted to determine the inhibitory effects of the plant extract on these enzymes. The results showed that vernonia amygdalina exhibited significant inhibition of both alpha-amylase and alpha-glucosidase enzymes. The study also evaluated the kinetic parameters of the inhibition process, including the type of inhibition and the inhibition constant. The findings of this study suggest that Vernonia amygdalina has the potential to be used as a natural inhibitor of alpha-amylase and alpha-glucosidase enzymes, which could lead to the development of new natural remedies for managing diabetes. These results are of interest to researchers studying natural product chemistry and drug development and inhibition of enzyme in bioreactors. Vernonia amygdalina inhibits alpha-amylase and alpha glucosidase activities but with greater inhibitory effects experienced in alpha glucosidase shows that plants tend to have higher inhibitory effect on alpha-glucosidase. With the obtain IC50 values it helps to provide insight into the mechanism of actions of an inhibitor by helping to determine the nature and strength of the interaction between the inhibitor and the enzyme or the biological process being inhibited. Acarbose which serves as inhibitors of these enzymes with greater effect on alpha-amylase but resulting to gastrointestinal adverse effects due to the accumulation of undigested carbohydrates becoming readily available for bacterial fermentation. With these outcomes the possibility exists that controlling glycemic complication is achievable by combining the inhibitory effect of Vernonia amygdalina and acarbose while reducing acarbose dose to alleviate anti-diabetic related adverse effects. Further investigation and studies are warranted in humans to help in glycemic control while in bioreactors this may include the usage of alpha-glucosidase and alpha-amylase as enzyme which similarly employs Vernonia amygdalina. It is noteworthy that the activity of these enzymes can be inhibited in bioreactors.
Examining the role of religious organizations in trauma support and healing within gun violence prevention efforts
Authors: Eromosele Favour Ojiemudia  , Samson Ajetomobi  , Oluseun Timothy Womiloju  , Ayodeji Samuel Adeusi  , Kaosara Temitope Adebayo  , Habeeb Olayinka Dauda
Published: December 2024

This scholarly examination explores the critical role of religious organizations in providing trauma support and facilitating healing within gun violence prevention initiatives. Through a rigorous, interdisciplinary analysis of diverse faith-based approaches, the research investigates how religious institutions strategically leverage their distinctive theological frameworks and deeply rooted community connections to address trauma resulting from gun violence.
The study conducts an in-depth exploration of successful trauma-informed religious counseling programs, examining innovative interfaith collaboration models and healing practices that synthesize spiritual wisdom with contemporary therapeutic methodologies. Critically, our research unveils the nuanced advantages religious organizations possess in trauma support, demonstrating their capacity to integrate spiritual guidance with evidence-based mental health interventies.
Empirical findings reveal that faith-based trauma interventions consistently achieve higher community engagement and more sustainable outcomes compared to secular alternatives, while simultaneously illuminating the complex challenges inherent in this emerging interdisciplinary field. This research contributes significant scholarly insights into faith-based trauma intervention strategies, offering a comprehensive framework for understanding how religious organizations can enhance comprehensive gun violence prevention efforts and improve trauma support services across diverse community contexts.
Integrating DevOps and Large Language Model Operations (LLMOps) for GenAI-Enabled E-commerce Innovations A Pathway to Intelligent Automation
Authors: Rahul Kalva
Published: December 2024

This study explores the integration of DevOps methodologies with Large Language Model Operations (LLMOps) to drive intelligent automation and innovation in e-commerce. It is our goal to forecast and examine consumer faith in online marketplaces by making use of GenAI and the neural computation powers of LLMs. The strategy's core goal is to improve confidence by means of a two-pronged approach: first, predictive modeling with LLMs; and second, causal analysis with QCA. In order to determine the degree of trust based on reviews, LLMs examine fundamental aspects of online shopping, such as product quality, customer service, refund policies, and delivery speed. At the same time, customer journey stages including product selection, delivery, and post-purchase assistance are uncovered by QCA as causal linkages between trust. The integration of LLMOps within a DevOps framework ensures efficient deployment and maintenance of AI models, fostering seamless innovation and operational agility. This hybrid approach offers e-commerce platforms actionable insights into enhancing customer trust while setting a benchmark for intelligent automation in the industry.
From Democracy to Dictatorship: The Economic Impact of Guinea's 2021 Coup
Authors: Paul Terlumun Bemgba  , Ene Vincent-Orugbo
Published: December 2024

The central thesis of this paper is the examination of economic management within the period of Alpha Conde and Colonel Mamady Doumbouya in Guinea. To achieve this objective, the scope of this paper was limited to the Guinea coup of 2021 which was incidental to the promulgation permitting Alpha Conde to seek two more terms in office even though he just won his third reelection bid. The paper adopted the content analysis of secondary materials such as journal articles, magazines, the internet, etcetera using the desk research methodology. The purposive technique was adopted for sample (document) selection. The presentation and discussion of data were done in prose. As demonstrated, there is indeed a relationship between political institutions and economic performance. While Guinea’s coup d’état provided the Guinean people with hope that their political and economic conditions may improve, the military’s assumption of power potentially made things worse for the Guinean people as can be seen with the GDP rate for 2020 and 2021. Aside from international disapproval of an unconstitutional takeover, Guinea’s economy suffered as a result of crippling sanctions. Regardless of regime type, there should be limited state intervention in the economy, leaders should eschew clientelist tendencies, and the promotion of bureaucratic capacities as measures to ensure effective economic management.
Designing policy frameworks for the future: Conceptualizing the integration of green infrastructure into urban development
Authors: Rasheed O. Ajirotutu  , Abiodun Benedict Adeyemi  , Gil-Ozoudeh Ifechukwu  , Obinna Iwuanyanwu  , Tochi Chimaobi Ohakawa  , Baalah Matthew Patrick Garba
Published: December 2024

This paper explores the critical role of green infrastructure in urban development, proposing a conceptual model for designing policy frameworks that effectively integrate sustainable practices into urban planning. Green infrastructure and low-impact development (LID) strategies are essential for addressing environmental challenges such as stormwater management, water quality, and biodiversity preservation. The paper discusses the benefits of green infrastructure in promoting social equity, enhancing public health, and fostering long-term sustainability in urban environments. It also examines regulatory tools, economic incentives, and public-private partnerships as key mechanisms for encouraging the adoption of green infrastructure. The proposed model provides policymakers and urban planners with a roadmap to create resilient and equitable urban spaces, ensuring environmental and social sustainability for future generations.
Role of family medicine physicians in management of Mpox Disease
Authors: Hamad Abdulaziz AlSubaie
Published: December 2024

Mpox, formerly known as monkeypox, has emerged as a significant public health concern. Family medicine physicians, due to their integral role in primary care and community health, are crucial in the management of Mpox. This literature review examines the responsibilities and strategies for family medicine physicians in the diagnosis, management, and prevention of Mpox. By analyzing recent studies and guidelines, this review aims to highlight best practices and identify gaps in current knowledge, offering a comprehensive overview of how family medicine physicians can effectively address Mpox within their practices
Verification of the analytical performance of the serum phosphorus assay on Abbott Architect ci8200
Authors: Sabrina Belmahi  , Oumaima Nassiri  , Abdessamad Amrani  , Amjad Idrissi  , El-houcine Sebbar  , Mohammed Choukri
Published: December 2024

This study aimed to evaluate the analytical performance of the serum phosphorus assay using the Abbott Architect ci8200® automated system in the biochemistry laboratory of CHU Mohammed VI, Oujda. Method verification was conducted following NF ISO 15189 standards and COFRAC guidelines, assessing key performance parameters such as repeatability, reproducibility, and measurement uncertainty. The colorimetric method for phosphorus determination demonstrated excellent precision, with coefficients of variation (CV) for repeatability ranging from 0.93% to 1.06% across low, medium, and high concentrations. Reproducibility assessments yielded CVs between 2.07% and 2.53%, indicating robust intra-laboratory performance. A comparative analysis between systems using the Bland-Altman method showed strong agreement, with a correlation coefficient of 0.997. Measurement uncertainties at all levels were within acceptable limits. These findings confirm the reliability and accuracy of the assay, highlighting its suitability for clinical diagnostics and its alignment with international accreditation standards.
Skin exfoliation with herbal face creams: A review
Authors: Deepak Pate  , Janki Sahu  , Sanjay Kumar  , Baburam Ratre  , Bhuneshwari Sahu  , Tilotma Sahu  , Gyanesh Kumar Sahu
Published: December 2024

Herbal cosmetics are beauty products containing herbal ingredients for physiological activities like healing, smoothing, and conditioning. The use of herbs in cosmetic production has grown, leading to a strong market for herbal cosmetics. Creams are semi-solid emulsions used for external use, providing a calming effect and shielding the skin from various conditions. Our research aims to develop a herbal moisturizer to reduce acne, treat skin conditions, and enhance facial brightness. Cosmetics are substances used to clean, beautify, or alter the appearance of the human body.
Herbal formulations have gained popularity as a result of the search for safe and effective skincare products because of their possible therapeutic advantages and low risk of side effects. The thinnest and most visible part of the body is the skin on the face. There are four types of skin: normal, dry, oily, and mixed. The skin of the face acts as an essential barrier against the external environment, just like other types of skin. Compared to other parts of the body, the skin on the face is far more delicate. It's critical to adhere to all recommended procedures and treatments in order to preserve beautiful, healthy skin. Skincare, usually referred to as skin integrity support, is a group of treatments intended to enhance skin health and attractiveness. These could include eating a healthy diet, limiting time spent in the sun, and using emollients as necessary.
Exfoliation, a process that removes dead skin cells, originated in Egypt, China, and Asia. Today, cosmetic products use scrubs and chemical peels, with some synthetic and botanical ingredients used as exfoliants.
Awareness of forensic medicine services staff in hail with appropriate infection control practices
Authors: Musleh Samil Reshidi  , Abdulah Saadi Algarni  , Mohammed Hamdan Alshammari  , Mohammad Ayed Alreshidi  , Mubarak Saad Alshammari  , Naif Sulaiman Alenezi  , Ahmed Mahal Alreshidi  , Mamdouh Awad Alonezi
Published: December 2024

The study provides a comprehensive evaluation of infection control awareness, implementation, and attitudes among forensic medical staff in Hail. Given the high-risk nature of forensic work, which frequently involves exposure to biological hazards and infectious materials, adherence to strict infection control measures is essential. The findings reveal a generally strong awareness and agreement on the importance of infection control practices among forensic staff. This is reflected in their recognition of the challenges faced and the value they place on formal training and adherence to protocols.
However, the study also highlights some areas needing improvement. Despite a high level of agreement on the necessity of infection control measures and their implementation, there are inconsistencies in practice adherence and understanding of certain infection control measures. For instance, while personal protective equipment (PPE) usage and sterilization protocols are generally well-regarded and applied, the responses indicate variability in their routine application and the overall understanding of infection control guidelines.
These findings underscore the need for ongoing efforts to enhance infection control practices within forensic medicine. Recommendations include strengthening training programs to address identified gaps, ensuring clearer and more comprehensive infection control guidelines, and improving the consistency of resource availability and application. Addressing these areas will help bridge the gap between theoretical knowledge and practical implementation, ensuring that forensic medical staff in Hail can better manage the risks associated with their work.
The study's insights are crucial for informing policy and practice improvements in forensic medical settings. By identifying current strengths and weaknesses, the research provides a foundation for developing targeted
interventions that will enhance safety and efficacy in forensic medicine. Ultimately, this research contributes to safeguarding both forensic medical professionals and the broader community by ensuring adherence to robust infection control standards, aligned with both national and international guidelines.
A review on antioxidant property containing red grapes of herbal medicine for breast cancer
Authors: Snehal Dhewale  , D. K. Vir  , Unnati Rajendrasing Rajput  , Yash Kishor Pendharkar  , Gurudatta D. Rasne  , Vardhanand Vijay Pawar
Published: December 2024

Breast cancer is a major cause of mortality among women worldwide, making the exploration of novel therapeutic strategies crucial. Among the various alternative treatments, herbal formulations have gained significant attention due to their therapeutic potential. This review focuses on the role of red grape, known for its antioxidant properties, in the prevention and management of breast cancer. The bioactive compounds found in red grapes, particularly resveratrol and polyphenols, exhibit potent anticancer effects through various mechanisms such as oxidative stress reduction, apoptosis induction, and inhibition of cancer cell proliferation. This article discusses the evidence supporting the inclusion of red grape in herbal formulations and its therapeutic potential in breast cancer treatment
Prognostic value of ultrasound and doppler imaging in the diagnosis and treatment of peripheral tuberculous lymphadenitis
Authors: Anvarova Ekaterina Vladimirovna
Published: December 2024

Background: Tuberculous lymphadenitis, a common form of extrapulmonary tuberculosis, poses diagnostic challenges due to its nonspecific clinical presentation. Traditional methods often require invasive procedures for confirmation, underscoring the need for reliable noninvasive techniques. Ultrasonography (US), Doppler imaging, and elastography have emerged as potential diagnostic tools for evaluating lymph node pathology, enabling detailed assessment of tissue characteristics and vascularization.
Objective: This study aims to evaluate the diagnostic accuracy and clinical value of combining ultrasonography, Doppler imaging, and elastography in the noninvasive diagnosis and management of peripheral tuberculous lymphadenitis.
Methods: A total of 160 patients suspected of having tuberculous lymphadenitis underwent ultrasonography, Doppler imaging, and elastography. Documented ultrasonographic characteristics included lymph node size, central necrosis, and hypoechoic areas. Doppler imaging assessed vascularization, while elastography provided strain ratios to measure tissue stiffness, distinguishing between purulent and fibrotic lymph nodes. Diagnostic accuracy was assessed using sensitivity, specificity, and area under the ROC curve (AUC), with microbiological confirmation as the gold standard.
Results: Ultrasonography identified abnormal lymph nodes in 90% of cases, with central necrosis observed in 60.6% of cases. Doppler imaging revealed increased peripheral vascularization in 72% of cases, while elastography identified necrotic (low stiffness) and fibrotic (high stiffness) nodes in 67.2% and 10.6% of cases, respectively. The combined modalities achieved a sensitivity of 93%, specificity of 88%, and an AUC of 0.92, indicating excellent diagnostic performance. Microbiological confirmation was achieved in 88.7% of cases.
Conclusions: The integration of ultrasonography, Doppler imaging, and elastography provides a highly accurate, noninvasive approach for diagnosing tuberculous lymphadenitis, reducing the need for invasive procedures. This multimodal approach holds significant potential for improving diagnostic workflows, particularly in resource-limited settings, and guiding clinical management by distinguishing between active and chronic disease stages.
Comparación de la estimulación por microvibración versus inhibidores de catepsina K a nivel molecular y celular: una revisión sistemática
Authors: Salgado Martínez Yomira , Villanueva Arriaga Rosina Eugenia , García López Salvador , Molina Frechero Nelly
Published: December 2024

Introducción: El hueso está en remodelación constante para mantener la estructura del tejido óseo que lo compone. Este es susceptible a cambios que pueden ser tanto favorables como perjudiciales, marcados por ciertas variables como lo son la edad, sexo, enfermedades, alteraciones hormonales, traumas, entre otras
Método: Debido a lo anterior se planteó la idea de estudiar que tratamiento es mejor en la regeneración del tejido óseo, comparando tratamientos farmacológicos (inhibidores de la catepsina K) contra tratamiento de estimulación micro-vibratoria o no farmacológicos.
Objetivo: Realizar una revisión sistemática de tratamientos con microvibraciones e inhibidores de la catepsina K en relación con la remodelación ósea. Para realizar una comparación entre la efectividad del tratamiento basado en micro-vibraciones y con inhibidores de la catepsina K, se realizó una revisión sistemática en nueve bases de datos (Wiley Online Library, Pubmed, Google Academic, Scopus, Science Direct, Scielo, Medline, EBSCO y SpringerLink).
Resultados: En este estudio se incluyeron 20 artículos, los cuales demostraron que ambos tratamientos mejoran el proceso de remodelado óseo.
Conclusiones: Tomando en consideración la revisión sistemática realizada, se ha determinado que el tratamiento de micro-vibraciones de baja intensidad alta frecuencia incrementa la cortical externa, sin embargo, el uso de inhibidores de la catepsina k, promete tratamientos innovadores en la regeneración del tejido óseo, no obstante, se requiere de más estudios en ambos tipos de tratamientos a nivel celular y molecular para determinar su mecanismo de acción.
Polypharmacy in the Elderly of an Educational Program in the Brazilian Capital: A Cross-Sectional Study
Authors: Da Costa Vinícius Vieira , Costa Camila de Oliveira , De Paula Alves Cássia Cristina , Da Silva Emília Vitória , Karnikowski Margô Gomes de Oliveira , Rinaldo Eduardo Machado de Oliveira
Published: December 2024

Introduction: The elderly correspond to the most medicalized group in society. Therefore, studies related to the use of medicines are important to improve policies that guarantee comprehensive care. The objective of this study was to investigate the polypharmacy among elderly individuals attending an educational program in the Federal District of Brazil and estimate the prevalence and associated variables.
Method: This is a cross-sectional study with 150 elderly individuals whose data were collected in the period from December 2022 to April 2023 by means of telephone calls.
Results: The prevalence of polypharmacy was estimated in 18.7%. The variables showing a positive association with polypharmacy were the following: health self-perceived as bad or very bad (PR = 8.9; 95 % CI 4.78 – 16.70), smoking (PR = 2.50; 95 % CI 1.06 – 5.89), systemic arterial hypertension (PR = 3.55; 95 % CI 1.40 – 9.00), diabetes mellitus (PR = 3.46; 95 % CI 1.67 – 7.18), depression (PR = 3.32; 95 %CI 1.58 – 6.75), multimorbidity (PR = 8.97; 95 % CI 1.26 – 64.10) and Charlson Comorbidity Index equal to or greater than 3 (PR = 7.21; 95 % CI 1.14 – 26.17).
Conclusions: The prevalence of polypharmacy and associated variables are corroborated by other Brazilian studies. Therefore, it is pointed out that healthcare teams should pay attention to this aspect of geriatric pharmacotherapy to favour the responsible use of medications and yield positive clinical outcomes.
Perfil de seguridad de Paxlovid® contra SARS-CoV2 en pacientes de un hospital en México
Authors: Chan Canche Belem Arieth , Arcos-Díaz Abraham , Argaez-Ojeda Kyra Angélica , Torres-Erazo Darwin Stalin , Marín-Alvarado Carmen Patricia , Bonnabel-Becerra Gustavo
Published: December 2024

Introducción: Debido al incremento de contagios de la variante Ómicron de la Enfermedad por Coronavirus 2019, la autoridad sanitaria mexicana autorizó el antiviral oral Paxlovid® para el tratamiento ambulatorio de pacientes con infección leve a moderada. Contando con un perfil de seguridad limitado, el objetivo fue describir las reacciones adversas y otros problemas de seguridad relacionados con el uso, tratados en un hospital de tercer nivel en México y compararlas con las reportadas en otros países.
Método: Serie clínica semilongitudinal prospectiva realizado en el Hospital Regional de Alta Especialidad de la ­Península de Yucatán entre 17 octubre 2022 y 10 julio de 2023. Se le dio seguimiento por llamada telefónica a los pacientes tratados con Paxlovid®, siendo cuestionados sobre las reacciones adversas presentadas durante el tratamiento.
Resultados: Se incluyeron 65 pacientes. La edad promedio fue 46,8±15,3 años. El 89,2 % (n=58) presentó una o más reacciones adversas y 13,8 % (n=9) suspendió el tratamiento debido a las mismas. Se identificaron un total de 132 reacciones adversas, 2±1 por paciente, siendo las más frecuentes de tipo leve (78 %) como sabor amargo, náuseas y cansancio. Se identificaron otras reacciones adversas no reportadas en el prospecto de Paxlovid®.
Conclusiones: Paxlovid® tiene un perfil de seguridad aceptable y equiparable con otros estudios, siendo consistente con la experiencia clínica previa y respaldando la seguridad del uso de la combinación de nirmatrelvir y ritonavir como opción terapéutica contra la Enfermedad por Coronavirus 2019.
The discovery learning and Google sites: Its application in learning the process of urine formation for high school students
Authors: Mustofa Ali , Hayuana Wachidah , Damopolii Insar , Ibrohim Ibrohim , Susilo Herawati
Published: December 2024

In the application of discovery learning in the classroom, the main source of science information is not the teacher, but various other sources that can be easily accessed by students. Learning sources that can be flexibly accessed by students are Google sites. This study was conducted to analyze how the implementation of discovery learning and Google sites in learning the formation of human urine. The research was conducted in one of the high schools in Malang. The students involved were grade XI. Data were collected through observation, teacher reflection sheets, learning implementation sheets (student and teacher activities), and student response questionnaires. The research data were narrated based on observations and learning implementation and student responses were calculated using percentages. The research findings show that the implementation of discovery learning and Google sites in learning the formation of human urine has changed the learning conditions of students for the better. High school students can actively answer teacher questions, are able to work on student worksheets, can work together well, discuss actively and draw conclusions. Google sites are a medium that can help students to find information related to the learning being carried out. Student responses related to learning scored 78.95 which is included in the good category. Collaborative activities among students can run well. Students agree that they do not forget the responsibilities given by their group to each individual.
Digital literacy level of prospective teacher students in the 4.0 industrial revolution era
Authors: Hartati Tri Asih Wahyu , Lestari Purwaning Budi , Istiawan Nurcholis , Darmawan Ericka
Published: December 2024

Digital literacy is an essential competency needed in the Industrial Revolution 4.0 era, driven by rapid technological advancements. This study aims to analyze the level of digital literacy of prospective teacher students in facing the Industrial Revolution 4.0 era, focusing on students’ demographics, namely age, gender and length of study. Survey method was administered in this study, involving 120 prospective teacher students from Universitas Insan Budi Utomo as the respondents. The data were collected through a questionnaire of 1-5 Likert scale, which included questions assessing students' digital literacy levels. The findings of this study portrayed data on students' digital literacy levels according to demographics (gender, age, and length of study). In general, the digital literacy level of Insan Budi Utomo University students is known to be in the “fairly good” category with an average score of 3.14 for the knowledge aspect and 3.20 for the usage aspect. The results of this study are recommended as a reference for designing learning experiences that empower digital literacy, supporting students in becoming more digitally proficient.
An analysis of primary school students' scientific literacy
Authors: Nasir Nur Indah Ririn Fitriani , Purwaningsih Endang , Ekawati Ratna , Yambi Tomás de Aquino Caluyua
Published: December 2024

The study aims to analyze the scientific literacy skills of elementary school students. In addition, differences in scientific literacy based on gender were also examined in this study. The study is quantitative and measures students' scientific literacy. Researchers investigated the literacy profile of sixth-grade students in one of the primary schools in Malang City. The target population was 107 sixth-grade students. The sampling technique was saturated, and the population was included in the sample. Data were collected using ten multiple-choice tests. The findings were analyzed by calculating the results of the validity and reliability tests, percentages, mean, and the Mann-Whitney test to calculate the differences in scientific literacy of boys and girls. The results showed that ten items were valid (sig. <0.05), and the reliability was 0.72. The results of the study showed that the less category dominated students' scientific literacy, while only 2.80% achieved excellence. The average total scientific literacy of students was less (45.51). There is no difference in the scientific literacy of girls and boys. It can be concluded from this study that the scientific literacy skills of sixth-grade primary school students are lacking but do not show significant differences between boys and girls. The results of this research are the basis for developing students' scientific literacy in the future by creating appropriate learning.