bluuebunny/crossref_metadata_2025 huggingface dataset:
Long non-coding RNAs involved in the regulatory network during porcine pre-implantation embryonic development and iPSC induction
Authors: Zhong Liang , Mu Haiyuan , Wen Bingqiang , Zhang Wei , Wei Qingqing , Gao Ge , Han Jianyong , Cao Suying
Published: April 2018

Long non-coding RNAs (lncRNA) play a key role in the orchestration of transcriptional regulation during development and many other cellular processes. The importance of the regulatory co-expression network was highlighted in the identification of the mechanism of these processes in humans and mice. However, elucidation of the properties of porcine lncRNAs involved in the regulatory network during pre-implantation embryonic development and fibroblast reprogramming to induced pluripotent stem cell (iPSC) has been limited to date. Using a weighted gene co-expression network analysis, we constructed the regulatory network and determined that the novel lncRNAs were functionally involved in key events of embryonic development during the pre-implantation period; moreover, reprogramming could be delineated by a small number of potentially functional modules of co-expressed genes. These findings indicate that lncRNAs may be involved in the transcriptional regulation of zygotic genome activation, first lineage segregation and somatic reprogramming to pluripotency. Furthermore, we performed a conservation and synteny analysis with the significant lncRNAs involved in these vital events and validated the results via experimental assays. In summary, the current findings provide a valuable resource to dissect the protein coding gene and lncRNA regulatory networks that underlie the progressive development of embryos and somatic reprogramming.
Prevalent metabolic derangement and severe thrombocytopenia in ABO-incompatible liver recipients with pre-transplant plasma exchange
Authors: Kwon Hye-Mee , Jun In-Gu , Lee JungBok , Moon Young-Jin , Jung Kyeo-Woon , Jeong Hye-Won , Park Yong-Seok , Song Jun-Gol , Hwang Gyu-Sam
Published: April 2018

Desensitisation with therapeutic plasma exchange (TPE) is essential for ABO-incompatible (ABO-I) liver transplants (LTs). However, excessive citrate load and coagulation disturbances after TPE have been poorly studied, in particular in cirrhotic patients with hypocapnic alkalosis, metabolic compensation and electrolyte imbalances. We retrospectively evaluated 1123 consecutive LT recipients (923 ABO-compatible [ABO-C], 200 ABO-I) from November 2008 to May 2015. TPE was generally performed a day before LT and blood sampling was performed before anaesthesia induction. We performed propensity score matching (PSM) and inverse probability treatment weighting (IPTW) analyses. In 199 PSM pairs, metabolic alkalosis was prevalent in ABO-I LT recipients (expectedly due to citrate conversion) with higher pH ≥ 7.50 (IPTW-adjusted odds ratio [aOR] = 2.23) than in ABO-C LT recipients. With increasing cirrhosis severity, the arterial pH and bicarbonate levels showed dose-dependent relationships, whereas mild hypoxaemia was more prevalent in ABO-I LT recipients. ABO-I LT recipients exhibited worsened hypokalaemia ≤3.0 mmol/l (17.6%, aOR = 1.44), hypomagnesaemia ≤1.7 mg/dl (27.6%, aOR = 3.43) and thrombocytopenia <30,000/µl (19.1%, aOR = 2.26) confirmed by lower maximal clot firmness (P = 0.001) in rotational thromboelastometry (EXTEM), which necessitated platelet transfusions. Preoperative identification of these change may prevent worsening of severe electrolyte disturbances and thrombocytopenia for optimal LT anaesthesia.
MicroRNA 199a-5p induces apoptosis by targeting JunB
Authors: Yan Mengjie , Yang Sibao , Meng Fanbo , Zhao Zhihui , Tian Zhisen , Yang Ping
Published: April 2018

MicroRNAs participate in a variety of physiological and pathophysiological processes in various organs including the heart. Our previous work revealed that the level of miR-199a-5p was significantly higher in failing hearts than in control hearts. However, whether it is associated with the progression of heart failure (HF) and mediates cardiomyocyte apoptosis remained unclear. In the present study, we used various biochemical and molecular biological approaches to investigate the changes in miR-199a-5p levels in failing hearts in a rat model induced by acute myocardial infarction. We found that miR-199a-5p levels in the heart increased with the progression of HF, and overexpression of miR-199a-5p significantly increased apoptosis in untreated H9C2 cells and potentiated angiotensin II-induced apoptosis. Thus, our results indicate that miR-199a-5p is involved in the progression of HF and mediates cardiomyocyte apoptosis. We also confirmed that JunB, a member of the activator protein-1 transcription factor family, is one of direct targets of miR-199a-5p via a dual-luciferase reporter assay and mutagenesis on the 3′ untranslated region of the JunB gene. Consistent with the above findings, overexpression of JunB in H9c2 cells suppressed cell apoptosis. Based on our findings, miR-199a-5p induces apoptosis by targeting JunB.
Application of droplet digital PCR in the analysis of genome integration and organization of the transgene in BAC transgenic mice
Authors: Nakagaki Ayumi , Urakawa Asuka , Hirano Shiori , Anami Takeru , Kishino Tatsuya
Published: April 2018

Transgenic (Tg) mice containing bacterial artificial chromosome (BAC) DNA are widely used for gene expression analysis and gene therapy models because BAC transgenes provide gene expression at physiological levels with the same developmental timing as endogenous genes. To ensure correct interpretation of transgene functions, investigation of the genomic organisation and integration of the BAC transgene is required. Here, we describe a reliable method based on droplet digital PCR (ddPCR) and inverse PCR to estimate copy number, genomic organisation and insertion sites of BAC transgenes in the mouse genome. We generated BAC Tg mice containing fragments of BAC clone RP23-59P20. ddPCR and iPCR analysis showed that the transgene consisted of five fragments of the BAC clone containing the Mkrn3 gene region, and that the transgene was inserted into Bckdhb, homozygous deletion of which causes the maple syrup urine disease phenotype. The ddPCR method described here should prove useful for analysis of genomic organisation and integration of BAC transgenes.
Structural defects in a nanomesh of bulk MoS2 using an anodic aluminum oxide template for photoluminescence efficiency enhancement
Authors: Kim TaeWan , Kim DongHwan , Choi Chan Ho , Joung DaeHwa , Park JongHoo , Shin Jae Cheol , Kang Sang-Woo
Published: April 2018

Two-dimensional (2D) materials beyond graphene have attracted considerable interest because of the zero bandgap drawbacks of graphene. Transition metal dichalcogenides (TMDs), such as MoS2 and WSe2, are the potential candidates for next 2D materials because atomically thin layers of TMDs exhibit unique and versatile electrical and optical properties. Although bulk TMDs materials have an indirect bandgap, an indirect-to-direct bandgap transition is observed in monolayers of TMDs (MoS2, WSe2, and MoSe2). Optical properties of TMD films can be improved by the introduction of structural defects. For example, large-area spatial tuning of the optical transition of bulk MoS2 films is achieved by using an anodic aluminum oxide (AAO) template to induce structural defects such as edge- and terrace-terminated defects in a nanomesh structure. Strong photoluminescence emission peaks with a band gap of 1.81 eV are observed, possibly because of radiative transition at the defect sites. This work shows that the AAO template lithography method has potential for the production of homogenous large-scale nanomesh structures for practical semiconductor processing applications in future MoS2-based electronic and optical devices.
Skillful prediction of hot temperature extremes over the source region of ancient Silk Road
Authors: Zhang Jingyong , Yang Zhanmei , Wu Lingyun
Published: April 2018

The source region of ancient Silk Road (SRASR) in China, a region of around 150 million people, faces a rapidly increased risk of extreme heat in summer. In this study, we develop statistical models to predict summer hot temperature extremes over the SRASR based on a timescale decomposition approach. Results show that after removing the linear trends, the inter-annual components of summer hot days and heatwaves over the SRASR are significantly related with those of spring soil temperature over Central Asia and sea surface temperature over Northwest Atlantic while their inter-decadal components are closely linked to those of spring East Pacific/North Pacific pattern and Atlantic Multidecadal Oscillation for 1979–2016. The physical processes involved are also discussed. Leave-one-out cross-validation for detrended 1979–2016 time series indicates that the statistical models based on identified spring predictors can predict 47% and 57% of the total variances of summer hot days and heatwaves averaged over the SRASR, respectively. When the linear trends are put back, the prediction skills increase substantially to 64% and 70%. Hindcast experiments for 2012–2016 show high skills in predicting spatial patterns of hot temperature extremes over the SRASR. The statistical models proposed herein can be easily applied to operational seasonal forecasting.
The fungus Aspergillus niger consumes sugars in a sequential manner that is not mediated by the carbon catabolite repressor CreA
Authors: Mäkelä Miia R. , Aguilar-Pontes María Victoria , van Rossen-Uffink Diana , Peng Mao , de Vries Ronald P.
Published: April 2018

In nature, the fungus Aspergillus niger degrades plant biomass polysaccharides to monomeric sugars, transports them into its cells, and uses catabolic pathways to convert them into biochemical building blocks and energy. We show that when grown in liquid cultures, A. niger takes up plant-biomass derived sugars in a largely sequential manner. Interestingly, this sequential uptake was not mediated by the fungal general carbon catabolite repressor protein CreA. Furthermore, transcriptome analysis strongly indicated that the preferential use of the monomeric sugars is arranged at the level of transport, but it is not reflected in transcriptional regulation of sugar catabolism. Therefore, the results indicate that the regulation of sugar transport and catabolism are separate processes in A. niger.
Topical pharyngeal anesthesia provides no additional benefit to propofol sedation for esophagogastroduodenoscopy: a randomized controlled double-blinded clinical trial
Authors: Sun Xiaotian , Xu Yang , Zhang Xueting , Li Aitong , Zhang Hanqing , Yang Teng , Liu Yan
Published: April 2018

Propofol sedation has been applied during esophagogastroduodenoscopy procedures, but whether topical pharyngeal anesthesia should be administered at the same time has rarely been reported. Our study examined the role of topical pharyngeal anesthesia in sedated endoscopies in a randomized controlled double-blinded clinical trial. A total of 626 patients who underwent sedated esophagogastroduodenoscopy were randomized into the experimental group (n = 313) or the control group (n = 313). The discomfort score, immediately and one day after the procedure, was not statistically significant [7.2 (5–9) vs. 7.5 (6–9), P = 0.210; 2.3 (0–3) vs. 2.6 (0–4), P = 0.095, respectively]. Two patients in the experimental group and three patients in the control group needed oral medication for pharyngeal discomfort (P = 0.354). The satisfaction score was 9.2 (8–10) in the experimental group and 8.9 (7–10) in the control group (P = 0.778). Lidocaine topical pharyngeal anesthesia in propofol-sedated esophagogastroduodenoscopy did not further reduce the pharyngeal discomfort or improve the satisfaction. This clinical trial was registered at ClinicalTrials.gov (ClinicalTrials.gov ID: NCT03070379).
Anisotropic diamond etching through thermochemical reaction between Ni and diamond in high-temperature water vapour
Authors: Nagai Masatsugu , Nakanishi Kazuhiro , Takahashi Hiraku , Kato Hiromitsu , Makino Toshiharu , Yamasaki Satoshi , Matsumoto Tsubasa , Inokuma Takao , Tokuda Norio
Published: April 2018

Diamond possesses excellent physical and electronic properties, and thus various applications that use diamond are under development. Additionally, the control of diamond geometry by etching technique is essential for such applications. However, conventional wet processes used for etching other materials are ineffective for diamond. Moreover, plasma processes currently employed for diamond etching are not selective, and plasma-induced damage to diamond deteriorates the device-performances. Here, we report a non-plasma etching process for single crystal diamond using thermochemical reaction between Ni and diamond in high-temperature water vapour. Diamond under Ni films was selectively etched, with no etching at other locations. A diamond-etching rate of approximately 8.7 μm/min (1000 °C) was successfully achieved. To the best of our knowledge, this rate is considerably greater than those reported so far for other diamond-etching processes, including plasma processes. The anisotropy observed for this diamond etching was considerably similar to that observed for Si etching using KOH.
Personality traits affecting judgement bias task performance in dogs (Canis familiaris)
Authors: Barnard Shanis , Wells Deborah L. , Milligan Adam D. S. , Arnott Gareth , Hepper Peter G.
Published: April 2018

Certain personality traits (e.g. anxiousness, fearfulness), are known to affect the cognitive processing of environmental stimuli, such as the judgement of ambiguous stimuli (judgement bias). Our aim was to assess if personality traits are predictive of a more or less ‘pessimistic’ or ‘optimistic’ judgement bias in the domestic dog. We assessed dog personality (N = 31) using two validated protocols: the Dog Mentality Assessment (standardised battery test) and the CBARQ (owner-based survey). We used a common task based on the animals’ latency to approach a bowl placed in one of three ambiguous positions (Near Positive, Middle, Near Negative) between a baited (Positive) and a non-baited food bowl (Negative) to assess judgement bias. Linear Mixed Model analyses revealed that dogs scoring higher on sociability, excitability and non-social-fear had shorter response latencies to bowls in an ambiguous location, indicating a more ‘optimistic’ bias. In contrast, dogs scoring higher on separation-related-behaviour and dog-directed-fear/aggression traits were more likely to judge an ambiguous stimulus as leading to a negative outcome, indicating a more ‘pessimistic’ bias. Results, partially consistent with previous findings in humans, indicate that personality plays a role in the cognitive processing of environmental stimuli in the domestic dog.
Intracellular glycolysis in brown adipose tissue is essential for optogenetically induced nonshivering thermogenesis in mice
Authors: Jeong Jae Hoon , Chang Ji Suk , Jo Young-Hwan
Published: April 2018

Release of fatty acids from lipid droplets upon activation of the sympathetic nervous system (SNS) is a key step in nonshivering thermogenesis in brown adipose tissue (BAT). However, intracellular lipolysis appears not to be critical for cold-induced thermogenesis. As activation of the SNS increases glucose uptake, we studied whether intracellular glycolysis plays a role in BAT thermogenesis. To stimulate BAT-innervating sympathetic nerves in vivo, we expressed channelrhodopsin-2 (ChR2) in catecholaminergic fibers by crossbreeding tyrosine hydroxylase-Cre mice with floxed-stop ChR2 mice. Acute optogenetic stimulation of sympathetic efferent fibers of BAT increased body temperature and lowered blood glucose levels that were completely abolished by the β-adrenergic receptor antagonist. Knockdown of the Ucp1 gene in BAT blocked the effects of optogenetic stimulation on body temperature and glucose uptake. Inhibition of glucose uptake in BAT and glycolysis abolished optogenetically induced thermogenesis. Stimulation of sympathetic nerves upregulated expression of the lactate dehydrogenase-A and -B genes in BAT. Optogenetic stimulation failed to induce thermogenesis following treatment with the LDH inhibitor. Pharmacological blockade and genetic deletion of the monocarboxylate transporter 1 completely abolished the effects of sympathetic activation. Our results suggest that intracellular glycolysis and lactate shuttle play an important role in regulating acute thermogenesis in BAT.
Solid-state electrical applications of protein and peptide based nanomaterials
Authors: Panda Sayak Subhra , Katz Howard E. , Tovar John D.
Published: April 2018

This review summarizes recent advancements in electrical properties and applications of natural proteins and mutated variants, synthetic oligopeptides and peptide–π conjugates.
Graphitization of Miscanthus grass biocarbon enhanced by in situ generated FeCo nanoparticles
Authors: Major Ian , Pin Jean-Mathieu , Behazin Ehsan , Rodriguez-Uribe Arturo , Misra Manjusri , Mohanty Amar
Published: April 2018

The synergistic activity of iron and cobalt nitrate has been highlighted by the generation of FeCo nanoparticles which enhanced the graphitization process of biomass into biocarbon.
Multi-element analysis of single nanoparticles by ICP-MS using quadrupole and time-of-flight technologies
Authors: Naasz Steffi , Weigel Stefan , Borovinskaya Olga , Serva Andrius , Cascio Claudia , Undas Anna K. , Simeone Felice C. , Marvin Hans J. P. , Peters Ruud J. B.
Published: April 2018

In this study, we investigate the capability of spICP-MS using time-of-flight and quadrupole mass analyzers to determine composition size distribution and concentration.
Comparative lipidomic profiling of the human commensal bacteriumPropionibacterium acnesand its extracellular vesicles
Authors: Jeon Jinseong , Park Seung Cheol , Her Jin , Lee Jae Won , Han Jin-Kwan , Kim Yoon-Keun , Kim Kwang Pyo , Ban Changill
Published: April 2018

Propionibacterium acnesis a lipophilic commensal bacterium mainly found on the skin and in the gastrointestinal tract. Pathophysiological effects ofP. acneshave recently been reported not only in acne progression but in various diseases.
Simultaneous tuning of martensitic transformation behavior, magnetic and mechanical properties in Ni–Mn–Sn magnetic alloy by Cu doping
Authors: Zhang Kun , Tan Changlong , Guo Erjun , Feng Zhicheng , Zhu Jiachen , Tong Yunxiang , Cai Wei
Published: April 2018

A new strategy of performance tuning is proposed, which shows that replacing Sn by Cu in the Ni47Mn38Sn15−xCux magnetic shape memory alloys can simultaneously tune their martensitic transformation behavior, magnetic and mechanical properties.
Detailed investigation on how the protein corona modulates the physicochemical properties and gene delivery of polyethylenimine (PEI) polyplexes
Authors: Zhu Dingcheng , Yan Huijie , Zhou Zhuxian , Tang Jianbin , Liu Xiangrui , Hartmann Raimo , Parak Wolfgang J. , Feliu Neus , Shen Youqing
Published: April 2018

Given the various cationic polymers developed as non-viral gene delivery vectors, polyethylenimine (PEI) has been/is frequently used inin vitrotransfection.
Rigid tetraarylene-bridged cavitands from reduced-symmetry resorcin[4]arene derivatives
Authors: Smith Jordan N. , Lucas Nigel T.
Published: April 2018

Two tetraaryl-extended macrocycles were prepared from resorcin[4]arenes. The C2v-symmetric isomer afforded a new rigid cyclooctaphenylene cavitand following oxidative cyclodehydrogenation.
Hydrogenation of silyl formates: sustainable production of silanol and methanol from hydrosilane and carbon dioxide
Authors: Koo Jangwoo , Kim Seung Hyo , Hong Soon Hyeok
Published: April 2018

Simultaneous production of methanol and silanols was achieved by hydrogenation of silyl formates readily obtained from silanes and CO2.
Cysteine-activated hydrogen sulfide (H2S) delivery through caged carbonyl sulfide (COS) donor motifs
Authors: Zhao Yu , Steiger Andrea K. , Pluth Michael D.
Published: April 2018

Cysteine-activated acrylate-functionalized thiocarbamates provide access to triggered COS/H2S donors.
Precursor control over the self-assembly of [2]catenanesviahydrazone condensation in water
Authors: Wang Cai-Yun , Wu Guangcheng , Jiao Tianyu , Shen Libo , Ma Ge , Pan Yuanjiang , Li Hao
Published: April 2018

By means of hydrazone condensation, a series of homo-[2]catenanes were self-assembled in high yields in water.
A planarized B-phenyldibenzoborepin: impact of structural constraint on its electronic properties and Lewis acidity
Authors: Ando Naoki , Kushida Tomokatsu , Yamaguchi Shigehiro
Published: April 2018

Planarization of B-phenyldibenzo[b,f]borepin allows π-expansion across the B-phenyl group and makes this scaffold a useful electron-accepting unit for donor-π-acceptor type fluorophores.
Topochemical transformation of single crystalline SrTiO3 microplatelets from Bi4Ti3O12 precursors and their orientation-dependent surface piezoelectricity
Authors: Wu Jie , Chang Yunfei , Lv Weiming , Jiang Guicheng , Sun Yuan , Liu Yingchun , Zhang Shantao , Yang Bin , Cao Wenwu
Published: April 2018

This work described the synthesis of SrTiO3 microplatelets with improved characteristics, explored the related topochemical mechanism, and discovered their orientation-dependent surface piezoelectricity.
La–La bonded dimetallofullerenes [La2@C2n]−: species for stabilizing C2n(2n= 92–96) besides La2C2@C2n
Authors: Li Qiao-Zhi , Zheng Jia-Jia , He Ling , Nagase Shigeru , Zhao Xiang
Published: April 2018

Theoretical investigations suggest that carbon cages C2ncould be captured as both electron reduced [La2@C2n]−with La–La bonding and pristine La2C2@C2nforms.
Identification of the binding site between bovine serum albumin and ultrasmall SiC fluorescent biomarkers
Authors: Dravecz Gabriella , Jánosi Tibor Z. , Beke Dávid , Major Dániel Á. , Károlyházy Gyula , Erostyák János , Kamarás Katalin , Gali Ádám
Published: April 2018

Combined experimental and theoretical studies propose a delayed diffusion model for describing the interaction between ultrasmall NPs and proteins.
Construction of strontium tantalate homo-semiconductor composite photocatalysts with a tunable type II junction structure for overall water splitting
Authors: Sun Feng , Wang Ping , Yi Zhouxiang , Wark Michael , Yang Junhe , Wang Xianying
Published: April 2018

The presence of at least two different strontium tantalates with a type II junction structure for efficient photocatalytic overall water splitting.
Characterization of the binding of strychnine with bovine β-lactoglobulin and human lysozyme using spectroscopic, kinetic and molecular docking analysis
Authors: Rudra Suparna , Jana Abhisek , Sepay Nayim , Patel Biman Kumar , Mahapatra Ambikesh
Published: April 2018

The binding interaction of a well known alkaloid strychnine (STN) with the mammalian milk protein β-lactoglobulin and human lysozyme has been explored by using several spectroscopic techniques along with computational studies.
One-step synthesis of photoluminescent catalytic gold nanoclusters using organoselenium compounds
Authors: Attia Yasser A. , Abdel-Hafez Shams H.
Published: April 2018

In this study, a facile and rapid method was developed to synthesize intensely photoluminescent catalytic gold nanoclusters (AuNCs) based on etching small citrate-capped gold nanoparticles using 4,6-dimethyl-2-pyridineselenol-3-caronitrile as a model for organoselenium compounds.
Nanowire lasers as intracellular probes
Authors: Wu Xiaoqin , Chen Qiushu , Xu Peizhen , Chen Yu-Cheng , Wu Biming , Coleman Rhima M. , Tong Limin , Fan Xudong
Published: April 2018

We investigate a cadmium sulfide (CdS) nanowire (NW) laser that is spontaneously internalized into a single cell to serve as a stand-alone intracellular probe.
Efficient synthesis of 3-sulfolenes from allylic alcohols and 1,3-dienes enabled by sodium metabisulfite as a sulfur dioxide equivalent
Authors: Dang Hang T. , Nguyen Vu T. , Nguyen Viet D. , Arman Hadi D. , Larionov Oleg V.
Published: April 2018

The new method enables a simple and efficient synthesis of 3-sulfolenes from 1,3-dienes and allylic alcohols using sodium metabisulfite.
Controllable fabrication of novel pH-, thermo-, and light-responsive supramolecular dendronized copolymers with dual self-assembly behavior
Authors: Yang ChangAn , Chen Ling , Huang He , Ji Tuo , Jiang YingXiang , Chen Xiaobo , Zhou CongShan
Published: April 2018

Novel tri-stimulus responsive supramolecular dendronized copolymers with dual self-assembly behavior are prepared, exhibiting fast and fully reversible phase transitions and trans–cis isomerization.
Controlled flexibility of porous coordination polymers by shifting the position of the –CH3 group around coordination sites and their highly efficient gas separation
Authors: Duan Jingui , Zhang Qiang , Wang Suna , Zhou Bihang , Sun Jiajia , Jin Wanqin
Published: April 2018

By adjusting the position of the methyl group, we found significant changes in the structural flexibility of the obtained PCPs, which also showed good gas separation ability.
Do two oxidants (ferric-peroxo and ferryl-oxo species) act in the biosynthesis of estrogens? A DFT calculation
Authors: Wang Xiang-Yun , Yan Hui-Min , Han Yan-Li , Zhang Zhu-Xia , Zhang Xiao-Yun , Yang Wen-Jing , Guo Zhen , Li Yan-Rong
Published: April 2018

Density functional theory calculations were performed in order to reveal the mysterious catalytic step of the biosynthesis of estrogens.
Application of a cation-exchange reaction of CuS nanoparticles and fluorescent copper nanoparticles in a DNA biosensor
Authors: Song Weiling , Zhang Nan , Luan Zhenzhu , Zhang Xiaoru , He Peng
Published: April 2018

A novel detection method based on cation-exchange of CuS nanoparticles combined with poly T-templated fluorescent Cu nanoparticles was developed and applied to the exonuclease III catalyst DNA biosensor.
Nematic colloidal knots in topological environments
Authors: Hashemi S. Masoomeh , Ravnik Miha
Published: April 2018

We demonstrate the role of environment, especially its topology, on defect formation and elastic fields, such as in nematic colloidal knots.
Biomimetic scale-resistant polymer nanocomposites: towards universal additive-free scale inhibition
Authors: Sheikhi Amir , Kakkar Ashok , van de Ven Theo G. M.
Published: April 2018

Scale-resistant membranes may be produced by incorporating nanoengineered anionic hairy cellulose crystals into model polymer matrices.
Eu and F co-doped ZnO-based transparent electrodes for organic and quantum dot light-emitting diodes
Authors: Luo Jingsong , Lin Jie , Zhang Nan , Guo Xiaoyang , Zhang Ligong , Hu Yongsheng , Lv Ying , Zhu Yongfu , Liu Xingyuan
Published: April 2018

A novel Eu and F co-doped zinc oxide (EFZO) thin film has been prepared by ion-assisted electron beam evaporation.
The role of fluorine-substitution on the π-bridge in constructing effective thermally activated delayed fluorescence molecules
Authors: Li Yun , Liang Jiao-Jiao , Li Hong-Cheng , Cui Lin-Song , Fung Man-Keung , Barlow Stephen , Marder Seth R. , Adachi Chihaya , Jiang Zuo-Quan , Liao Liang-Sheng
Published: April 2018

The fluorination on the π-bridge can obviously affect the photophysical behavior of the emitters and thus improve the device performance.
Inkjet printing of specular holograms based on a coffee-ring effect concave structure
Authors: Slabov Vladislav , Vinogradov Alexandr V. , Yakovlev Aleksandr V.
Published: April 2018

The proposed method for creating specular holograms on a variety of surface materials is based on creating a three-dimensional surface microstructure by controllable ink deposition.
The intragenic epistatic association of ADD3 with biliary atresia in Southern Han Chinese population
Authors: Wang Zhe , Xie Xiaoli , Zhao Jinglu , Fu Ming , Li Yonglan , Zhong Wei , Xia Huimin , Zhang Yan , Zhang Rui-Zhong
Published: April 2018

Biliary atresia (BA) is a multifactorial pathogenic disease with possible genetic components. As a member of membrane skeletal proteins in the liver and bile ducts, a haplotype composed by five single nucleotide polymorphisms (SNPs) on adducin 3 (ADD3) has been identified as associated with BA. However, limited study was designed to further elaborate the mutual relationship amongst those replicated SNPs to disease. We selected three susceptibility SNPs in ADD3 and conducted a replication study using 510 BA cases and 1473 controls to evaluate the individual function of the SNPs and further stratified the potential roles with disease and its subclinical features. Two SNPs in ADD3 were replicated as associated with BA (1.60E-04 ≤ P≤1.70E-04, 1.33 ≤ odds ratio (OR) ≤ 1.58 for rs17095355, 2.10E-04 ≤ P≤5.30E-04, 1.26 ≤ OR ≤ 1.57 for rs2501577). Though we failed to replicate the individual association of rs10509906 to disease, the intragenic epistatic effect between rs10509906 and rs2501577 was suggested as exhibiting susceptibility to BA, further cross-validated by multifactor dimensionality reduction (MDR) (P=0.068, OR = 1.37), which may explain extra hidden heritability of ADD3 to BA. Furthermore, through subclinical stratification, we also observed the association of risk to disease mainly came from the female patients.
The prognostic significance of preoperative serum albumin in urothelial carcinoma: a systematic review and meta-analysis
Authors: Liu Jing , Wang Fang , Li Shaohong , Huang Wenhui , Jia Yanjuan , Wei Chaojun
Published: April 2018

Preoperative serum albumin has been considered to be closely correlated with the prognosis of various cancers, including urothelial carcinoma (UC). However, to date, this conclusion remains controversial. The aim of this meta-analysis is to investigate the prognostic significance of preoperative serum albumin in UC. A literature search was performed in PubMed, Web of Science, Embase, and Cochrane Library up to 4 July 2017. Herein, a total of 15506 patients from 23 studies were enrolled in our meta-analysis. Decreased preoperative serum albumin level predicted poor overall survival (OS) (HR = 1.88, 95% CI: 1.44–2.45, P<0.0001), cancer-specific survival (CSS) (HR = 2.03, 95% CI: 1.42–2.90, P=0.0001), recurrence-free survival (HR = 1.85, 95% CI: 1.15–2.97, P=0.01), 30-day complications (30dCs) after surgery (odds ratio (OR) = 1.93, 95% CI: 1.16–3.20, P=0.01), and 90-day mortality after surgery (OR = 4.24, 95% CI: 2.20–8.16, P<0.001). The subgroup analyses indicated that low preoperative serum albumin level is still positively associated with a worse prognosis of UC based on ethnicity, cut-off value, tumor type, analyses type, and sample size. Our meta-analysis indicated that reduced preoperative serum albumin level was a predictor of poor prognosis of UC.
Structure and fragmentation of a high line-mass filament: Nessie
Authors: Mattern M. , Kainulainen J. , Zhang M. , Beuther H.
Published: April 2018

Context. An increasing number of hundred-parsec-scale, high line-mass filaments are being detected in the Galaxy. Their evolutionary path, including fragmentation towards star formation, is virtually unknown.

Aims. We characterize the fragmentation within the hundred-parsec-scale, high line-mass Nessie filament, covering size-scales in the range ~0.1–100 pc. We also connect the small-scale fragments to the star-forming potential of the cloud.

Methods. We combine near-infrared data from the VISTA Variables in the Via Lactea (VVV) survey with mid-infrared Spitzer/GLIMPSE data to derive a high-resolution dust extinction map for Nessie. We then apply a wavelet decomposition technique on the map to analyze the fragmentation characteristics of the cloud. The characteristics are then compared with predictions from gravitational fragmentation models. We compare the detected objects to those identified at a resolution approximately ten times lower from ATLASGAL 870 μm dust emission data.

Results. We present a high-resolution extinction map of Nessie (2″ full-width-half-max, FWHM, corresponding to 0.03 pc). We estimate the mean line mass of Nessie to be ~627 M⊙ pc−1 and the distance to be ~3.5 kpc. We find that Nessie shows fragmentation at multiple size scales. The median nearest-neighbor separations of the fragments at all scales are within a factor of two of the Jeans’ length at that scale. However, the relationship between the mean densities of the fragments and their separations is significantly shallower than expected for Jeans’ fragmentation. The relationship is similar to the one predicted for a filament that exhibits a Larson-like scaling between size-scale and velocity dispersion; such a scaling may result from turbulent support. Based on the number of young stellar objects (YSOs) in the cloud, we estimate that the star formation rate (SFR) of Nessie is ~371 M⊙ Myr−1; similar values result if using the number of dense cores, or the amount of dense gas, as the proxy of star formation. The star formation efficiency is 0.017. These numbers indicate that by its star-forming content, Nessie is comparable to the Solar neighborhood giant molecular clouds like Orion A.
Matched filter in low-number count Poisson noise regime: Efficient and effective implementation
Authors: Vio R. , Andreani P.
Published: April 2018

The matched filter (MF) is widely used to detect signals hidden within the noise. If the noise is Gaussian, its performances are well-known and can be described in an elegant analytical form. The treatment of non-Gaussian noises is often cumbersome as in most cases there is no analytical framework. This is true also for Poisson noise which, especially in the low-number count regime, presents the additional difficulty to be discrete. For this reason in the past methods have been proposed based on heuristic or semi-heuristic arguments. Recently, an analytical form of the MF has been introduced but the computation of the probability of false detection or false alarm (PFA) is based on numerical simulations. To overcome this inefficient and time-consuming approach, we propose here an effective method to compute the PFA based on the saddle point approximation (SA). We provide the theoretical framework and support our findings by means of numerical simulations. We also discuss the limitations of the MF in practical applications.
IoT-Based Car's Parking Monitoring System
Authors: Dwiputra Albertus Ega , Khoswanto Handry , Sutjiadi Raymond , Lim Resmana
Published: April 2018

Internet-of-things-based technologies have advanced so much and helped public necessities. The use of IoT at a parking lot will help vehicle users to know the availability of a parking location through smartphones. This IoT-based parking system is created by using controllers, sensors, servers and cloud. Controllers and sensors will be placed on the ceiling of each parking slots to detect the presence of a car. Server collect the results of the sensors and store them in Cloud. System test is conducted by installing three sensor circuits and server in a parking lot. The tests consist of measuring time that required for data transmission and the rate of success of data transmission from the parking lot to the Cloud. Based on above tests, it is observed that the sensor circuit and Radio Frequency Identification are able to transmit the parking lot data without error. This system require maximum 1 min to update parking lot data. The process of obtaining data until the data being stored in Cloud takes 12 s and the process of acquiring parking condition data from Cloud to smartphone takes 30 s. The accuracy level of parking lot data transfer is 100 %.
Green Industrial System in Indonesia
Authors: Handoko Fourry , Nursanti Ellysa , Gatot  , Edwin Tjahjadi Martinus , Hutabarat Julianus , Mulyadi Lalu , Kustamar
Published: April 2018

The environmentally friendly manufacturing influences the worldwide community both private and public to run the concept of green productivity. The concept of green productivity drives the organisation to seek integration of sustainable environmental management and environmentally friendly production system design. The lack of green and sustainable concept have reduced the competitiveness of the organisation due to the low capability to meet the international standard of ISO 14000. One of the important thing of being ‘green’ is our capability to deal with the pollution. Continuous improvement approach to achieve green productivity is an effort to increase sustainable competitiveness by maintaining green product and reducing the pollution. The continuous improvement to achieve the capability to overcome the pollution problem will lead into tangible and intangible benefit. It is therefore the green productivity is crucial. In this research, the concept of green produtivity and continuous improvement approah are utilised to overcome the problems of pollution in manufacturing industries.
Uniform and Non-Uniform Image Enlargement Based on the Window Kernel
Authors: Somawirata I Komang , Prio Hartono Bambang , Herbasuki Teguh , Soetedjo Aryuato
Published: April 2018

Several different of image resizing methods have been proposed. However, resizing image in different ratio produces non proportional feature image enlarged and the enlarged image in different ratio with retaining the salient content is limited. This paper proposes an image enlargement method with edge improvement and inpainting method. This method consists of two steps. First, the image enlargement method is used for enlarging an image to the minimum size of the target image. Second, image inpainting method is used for obtaining the full-size image. We have evaluated the proposed method for enlarging an image uniformly and it compares with the typical of image enlargement methods. The uniform image enlarged and image enlarged in different ratio using the proposed method have been presented.
Data Mining Application using Association Rule Mining ECLAT Algorithm Based on SPMF
Authors: Reynaldo Jason , Boy Tonara David
Published: April 2018

Data mining is an important research domain that currently focused on knowledge discovery database. Where data from the database are mined so that information can be generated and used effectively and efficiently by humans. Mining can be applied to the market analysis. Association Rule Mining (ARM) has become the core of data mining. The search space is exponential in the number of database attributes and with millions of database objects the problem of I/O minimization becomes paramount. To get the information and the data such as, observation of the master data storage systems and interviews were done. Then, ECLAT algorithm is applied to the open-source library SPMF. In this project, this application can perform data mining assisted by open source SPMF with determined writing format of transaction data. It successfully displayed data with 100 % success rate. The application can generate a new easier knowledge which can be used for marketing the product.
RFID and IOT for Attendance Monitoring System
Authors: Dedy Irawan Joseph , Adriantantri Emmalia , Farid Akh
Published: April 2018

In recent years, RFID technology has been widely used in various sectors, such as in-education, transportation, agriculture, animal husbandry, store sales and other sectors. RFID utilization in education is student attendance monitoring system, by using Internet of Things (IoT) and Cloud technology, it will produce a real time attendance monitoring system that can be accessed by various parties, such as lecturer, campus administration and parents. With this monitoring system if there are students who are not present can be immediately discovered and can be taken immediate action and the learning process can run smoothly.
Automatic Essay Scoring in E-learning System Using LSA Method with N-Gram Feature for Bahasa Indonesia
Authors: Setiadi Citawan Rico , Christanti Mawardi Viny , Mulyawan Bagus
Published: April 2018

In the world of education, e-learning system is a system that can be used to support the educational process. E-learning system is usually used by educators to learners in evaluating learning outcomes. In the process of evaluating learning outcomes in the e-learning system, the form type of exam questions that are often used are multiple choice and short stuffing. For exam questions in the form of essays are rarely used in the evaluation process of educational because of the difference in the subjectivity and time consuming in the assessment process. In this design aims to create an automatic essay scoring feature on e-learning system that can be used to support the learning process. The method used in automatic essay scoring is Latent Semantic Analysis (LSA) with n-gram feature. The evaluation results of the design features automatic essay scoring showed that the accuracy of the average achieved in the amount of 78.65 %, 58.89 %, 14.91 %, 71.37 %, 64.49 % in the LSA unigram, bigram, trigram, unigram + bigram, unigram + bigram + trigram.
Implementation of Winnowing Algorithm Based K-Gram to Identify Plagiarism on File Text-Based Document
Authors: Nurdiansyah Yanuar , Nur Muharrom Fiqih , Firdaus
Published: April 2018

Plagiarism occurs when the students have tasks and pursued by the deadline. Plagiarism is considered as the fastest way to accomplish the tasks. This reason makes the author tried to build a plagiarism detection system with Winnowing algorithm as document similarity search algorithm. The documents that being tested are Indonesian journals with extension .doc, .docx, and/or .txt. Similarity calculation process through two stages, the first is the process of making a document fingerprint using Winnowing algorithm and the second is using Jaccard coefficient similarity. In order to develop this system, the author used iterative waterfall model approach. The main objective of this project is to determine the level of plagiarism. It is expected to prevent plagiarism either intentionally or unintentionally before our journal published by displaying the percentage of similarity in the journals that we make.
The Design of E-Commerce System in the Shrimp Paste Industry using the Method of Structured Analysis and Design Technique (SADT) to Increase Marketing
Authors: Nurdiansyah Yanuar , Wijayanto Feri , Firdaus
Published: April 2018

The E-Commerce system in the shrimp paste industry is designed to increase the marketing and branding of Payangan shrimp paste. The shrimp paste produced by KUB (Kelompok Usaha Bersama—Business Group) and Poklahsar (Kelompok Pengolah Pemasaran—Marketing Processing Group) consisting of a number of joint household industries is yet to meet the sales number set. Shrimp paste has several variants, such as the processed one, the raw one and one in the form of powder which constitute the result of the development of maritime research group of Universitas Jember. The target market of the product is both national and international, especially for the powder shrimp paste which is the recent innovation of the maritime research group. It is considered to be a possibility to increase the sales figures and to decrease the marketing costs by optimizing the use of the internet. In order to do so, a system should be design using Structured Analysis and Design Technique (SADT) to build an e-commerce application. It is expected that the E-Commerce application can increase the sales of the shrimp paste and reach a wider number of consumers.
Optimized Matching Lift Unit Transmission Ratio of Engine Driven Ducted Fan
Authors: Xiao Senlin , Qiao Hongxin , Xu Guanxiong , Luo Guailin , Ma Chao , Guo Zhiyong , Zhang Depeng
Published: April 2018

As a kind of VTOL technology, ducted fan is not only used by many kinds of aircrafts, but also one of the trends of the future aircraft lift system, and attracts more and more attention. For an engine driven ducted fan lift unit, involving the engine and ducted fan matching problem, the form of transmission and transmission ratio are the key design parameters. In order to design and develop a ducted fan aircraft reasonably, a thrust test platform was set up to connect the engine with the ducted fan through the belt driving. The matching relationship between the engine and the transmission system was experimentally studied and the optimal transmission ratio was determined. The results showed that the optimal transmission ratio for the engine 1 is 2.2:1, and for the engine 2, the optimal transmission ratio should be 2.95:1 based on the current ducted and movable blade aerofoil design. At this time, the lift will exceed 130 kg•f, meeting the aircraft's original design requirements.
A Study on the Design of Rural Material Flow System Based on the Traditional Chinese Twenty-four Solar Terms - A Case Study of Lifengjie in Liyang City, Jiangsu Province, China
Authors: Xie Xiao-Yu , Fan Sheng-Xi
Published: April 2018

In the view of Chinese traditional twenty-four solar terms, the circulation of various substances in the material flow system of base production and life is systematically analyzed, and on the basis of the existing system problem point, as well as by combining with the concept of the twenty-four solar terms and the system design method, the author reconstructs each subsystem of the base material flow system, moreover, the author eventually connects the subsystems and reconstructs a material flow system conforming to the traditional Chinese solar terms and conforming to the requirements of ecological sustainability.
Survey, Research And Prospect Of Signage Systems In National Parks In Yunnan Province
Authors: wenjuan XU , shengxi FAN
Published: April 2018

The Signage System is essential to establishing a national park. The authors conducted surveys, analysis and research of identification signs, informational sign, directional signs and functional signs from the signage systems adopted by five national parks in Yunnan Province. Relying on the results, with reference to industry experience, years of research related to national park, successful cases of overseas national parks and the current signage systems across China’s national parks, the paper aims to explore future development strategies of national park signage systems that are suitable for China.
Structural Performance Evaluation for Vibration-based Energy Harvester utilized in Railway Vehicle
Authors: Kang Ki-Weon , Jin Ji-Won
Published: April 2018

This study aims to assess the structural performance and structural integrity of vibration energy harvester (VEH). For this, the structural performance test were conducted to identify the natural frequency and structural response against frequency. And then, static structural analysis was performed using finite element analysis to investigate the failure critical locations (FCLs). Finally, we conducted the frequency response analysis in frequency domain to obtain the structural response with frequency and investigate the structural integrity of VEH. Using the above results, we assessed the structural performance and structural integrity of two types of VEHs.
Transverse and Longitudinal Stress Analysis in Reinforced Welded Oil Branched Pipes
Authors: Safari H , Pourrajab R , Yaghootian A
Published: April 2018

Welding process results in the non-uniform distribution of heat. Combined with thermal strain, plastic deformation and welding-induced distortion, it causes important problems such as failure. This study models welding process in a 12×16 split tee junction using finite element. This junction is a reinforcing branch used in the hot taping of oil pipe line. The model is studied in 3D state. This zone, i.e. heat affected zone (HAZ) is of high importance due to the existence of a severe temperature gradient and stress in the vicinity of HAZ. This study analyses single pass butt welding with a cooling time of 2700 seconds. In order to apply boundary conditions to the model, the studied structure should be in Free State according to practical procedure. The main aim of this simulation is to analyse Longitudinal and transverse residual stresses originated from co-directional and opposite-directional welding. This joint is formed of two semicircles welded to each other as linear single pass welding. Two welders simultaneously welded both sides of the pipe.