bluuebunny/crossref_metadata_2025 huggingface dataset:
Students’ Motivation to Learn English Using Mobile Applications: The Case of Duolingo and Hello English
Authors: Hidayati Tuti , Diana Sari
Published: June 2022

The development of language learning mobile application soft-wares (apps) for smart mobile devices such as smartphones and tablet computer has risen amazingly in these recent days. These apps were continuously reported to be highly potential to support the students to learn the target language. This study introduced two free English learning apps to the students and investigated how they made use of the apps to support their English learning. More specifically, it examined how their English motivation in learning English is, how they used the apps, and whether their different level of motivation influenced the time they spent in accessing the apps. The study was conducted in a mixed method approach utilizing daily journal and questionnaire as the instruments to collect data. The finding pointed that the students were considerably active in using both of the apps. They could enjoy the practicality and flexibility of learning English by the apps despite some superficial engagement. In addition, although studentsâ€™ English learning motivation was found to have no influence on the amount of time spent in using the apps, their positive response toward using the apps was a potential indication to foster independent English learning outside the classroom. A further detailed finding was discussed along with important issues in the current trends of mobile language learning.
Peran Modal Sosial Dalam Program Penanggulangan Kemiskinan Di Kelurahan Betet Kecamatan Pesantren Kota Kediri
Authors: Al-Amin Taufiq
Published: June 2022

So far an approach in overcoming poverty, both at the national, regional and local, generally is with a purely economic approach. The problem of poverty seems to be simply understood as a problem of lack of income, so that the prevention programs which are carried out especially by the government focus only on the provision of assistance in the field of capital, the provision of subsidies, aid equipment and the like. This paper uses the form of social capital theory to understand, map out and promote poverty reduction by optimally utilizing social capital in the community. By utilizing social capital theory of Bourdieu, Coleman and Putnam, this research takes place in the Betet Village, Pesantren, Kediri City as the unit of analysis. The basic consideration of the location chosen is that Betet village is one of village areas in Kediri which implements poverty reduction programs since 2009 until now. The result shows that the poverty reduction in Betet village is implemented through a series of stages called PNPM Mandiri Urban cycle; it is started with a reflection of poverty, self power-mapping, determination of a medium-term program of poverty reduction programs. The characteristics of social capital of Betet Village community has grown and developed far before the PNPM program is implemented. The characteristics of social capital includes trust, links that has formed, values and norms that are awakened, participation and pro-active action. The existence of social capital contributes positively to their poverty reduction programs that emphasize community participation in various activities.
Persepsi Guru Pamong Terhadap Pelaksanaan Praktik Pengalaman Lapangan (PPL) Mahasiswa
Authors: Fanani Moh. Zainal
Published: June 2022

This research aims at getting a picture of guardian teachersâ€™ perception in MTsN, MAN, and SMAN in Kediri city toward pedagogical, professional, personal and social competences of PPL students of Tarbiyah department of STAIN Kediri in 2005. The research method used is a descriptive qualitative. The findings show that the average score for pedagogical competence is 69.13 % which is included in good criteria. The average score for professional competence is 72.36 % which is included in good criteria. The average score for personal competence is 75.97 % which is included in good criteria. Furthermore, the average score for social competence is 75.09 % which is included in good criteria. Therefore, it can be concluded that the guardian teachersâ€™ perception in MTsN, MAN, and SMAN in Kediri city toward the implementation of PPL (Praktek Pengalaman Lapangan) of Tarbiyah students of STAIN Kediri is good with average score 73.14 %.
Implementasi Kebijakan Kabupaten Layak Anak Di Kabupaten Probolinggo
Authors: Ni’mah Mamluatun
Published: June 2022

Probolinggo has done the policy of planning worthy children regency. It can be said that Probolinggo has just step up to do that policy. The purpose of the research is to describe the implementation of planning worthy children regency in Probolinggo and to know the factors that support and embedded the success of the policy. The research used qualitative approach by descriptive research. The result of the research showed that the implementation of worthy children policy used Darwin theory by doing 3 steps: interpreting, organizing and applying. The factors that supports its success is the commitment of departments and the leader in fulfilling the facilities and budgeting, although the ego-sectoral of departments were still exist. This could slow up the coordination and the success of KLA. In sort, it needs more intentional coordination and the same commitment and paradigm from the regency to rural level.
Efektivitas Self Assessment dan Peer Assessment Dalam Pembentukan Karakter Siswa
Authors: Wijayanti Anita
Published: June 2022

Measurement of student attitudes can be done through self-assessment and peer assessment which is a component of assessment in Curriculum 2013. Therefore the researcher wants to show how much effectiveness of self-assessment and peer assessment to form the character of student. With the formulation of the problem as follows: How the implementation of self-assessment and peer assessment to be effective in shaping the character of students? The results of this study show that; Self-assessment and peer assessment that is part of the assessment of the 2013 curriculum is the most effective assessment technique in shaping the character of the students. The character can have a positive impact, and if a positive personality has been established (self-actualization) then intellectual development (knowledge and skills) will also increase. This can be applicable in all areas of learning and will contribute to understanding the concepts within it.
Manajemen Pengembangan Pembelajaran Kitab Kuning
Authors: Hanani Nurul
Published: June 2022

Kitab kuning viewed as theory and values contributor that followed al-Quran and Hadis Nabi as a background. In pesantren world, kitab kuning position are very strategic because it used as text book, references, and curriculum within pesantren education system. Aside from being religion procedure guideline,kitab kuning also functioned as universalreferences on responding every life challenge among pesantren people. Presevartion of learning method with kitab kuning in pesantren has been running constantly and culturally being special characteristic of pesantren. There is a few kitab kuning categorization which is based on its'characteristic, meaning content, serving proportion, writing creativity, and description appearance. The learning method of kitab kuning in salafiyah pesantren will not be separated from conventional traditional method use. These are few learning method we talking about; wetonan or bandongan, sorogan and hafalan (tahfidz) and munazharah (musyawarah/muzkarah). There is also learning evaluation in the learning method of kitab kuning.
Analisis Kritis Sistem Penyelenggaraan Manajemen Pembelajaran Pendidikan Islam Di Indonesia Dalam Kemasan Scientific Learning
Authors: Zaharoh Irma
Published: June 2022

This Articles depart from the glasses Implementation of Islamic education management that until now still experiencing significant constraints. This happens because the lack of familiarity of educational management concepts in Islamic educational institutions. The issues discussed in this journal article include: What is the Basic Concept of Management of Learning? How is the Islamic Education Institution in Indonesia? And how the System of Implementation of Islamic Education Learning Management in Indonesia (in Packaging Scientific Learning). The basic concept of learning management at least there are three basic elements that must be managed in the context of implementation of education management in Islamic educational institutions, namely: student management, management personnel, and curriculum management and teaching programs. As stated in Law No. 20 of 2003 on National Education System, Educational Institutes are grouped into three groups, namely Formal Islamic Education, Non-Formal Islamic Education, and In-Formal Islamic Education. Implementation of Education System in Indonesia has been arranged clearly in the Act SISDIKNAS then translated into Government Peratuaran and then operated in Meneteri Peratuaran.
Konsep Nasikh Mansukh Jalaluddin Al-Suyuti Dan Implikasi Metode Pengajarannya Di Perguruan Tinggi
Authors: Masrur Imam
Published: June 2022

Ali ibn Abi Thalib said, a judge without nasikh-mansukh knowledge can make damages. Imams said, everyone forbidden interpret al-Qur'an before he knows nasikh-mansukh. But, many university students can't detail nasakh verses, many literatures don't detail it, and teaching process isn't appropriate. It causes they get misunderstanding in determining of Islmic law. To limit the discussion, this article will explore and analyze nasikh-mansukh concept of Jalaluddin al-Suyuti and the implication in teaching process. This article showed that Jalaluddin al Suyuti explores nasikh-mansukh concept completely until mapping nasakh verses. Mapping nasakh verses are main poin in understanding nasikh-mansukh. Without it, someone become misunderstanding in determining of Islamic law. Finally, this article concluded that concept nasikh-mansukh of Jalaluddin al-Suyuti can support teaching process how to understand nasikh-mansukh corectly toward university students.
Teknik Komunikasi Persuasif Buya Yahya Pada Ceramah “Apa Dan Bagaimana Hijrah Itu?”
Authors: Dia Kelaut , Wahyuni Sri
Published: June 2022

KH. Yahya Zainul Ma'arif (Buya Yahya) in the lecture "What and How Is Hijrah?", There is a persuasive communication technique, because there are many positive responses from mad'u. The existence of positive audience participation on the message conveyed, indicates the successful application of persuasive communication techniques. This study explains Buya Yahya's persuasive communication technique in the lecture "What and How Is Hijrah?". The study methodology is a qualitative researcher with the Philipp Mayring content analysis method, namely the research used to examine the content of messages in a communication process, in this study the content of da'wah messages. This study used video transcribed into text, then analyzed using a coding agenda with the patterns and categories of each persuasive communication technique used in this study. The data were collected through observation of broadcasts on the Al-Bahjah TV Youtube channel in the video lecture entitled "What and How Is Hijrah?". As a result, there are seven persuasive communication techniques used by Buya Yahya in his lecture "What and How Is Hijrah?" namely: association technique, integration technique, reward technique or “pay-off” technique, “Putting it up to you” technique, transfer technique, “bandwagon” technique, “don't ask if” technique and “ask which” technique. With the persuasive communication techniques used by preachers in conveying their da'wah messages, hopefully that mad'u can easily understand, so the purpose of da'wah communication is easily achieved.
Praktik Kepemimpinan Tranformasional Dalam Organisasi Islam (Studi Tentang Kepemimpinan Umar Bin Khattab Dalam Peristiwa Pembebasan Ibukota Persia – Madain)
Authors: Faridh Tri Ahmad
Published: June 2022

This study aims to describe the practice of transformational leadership, specifically regarding the practice of the components of transformational leadership applied by Umar bin Khattab in the event of the liberation of the Persian capital-Madain. This study method is qualitative-non-experimental-descriptive. The data collection used the documentation method with secondary data sources, namely the life history of Umar bin Khattab written by historians such as Muhammad Husain Haekal, Ali Muhammad AshShalabi, and Musthafa Murad. Data analysis used the Miles and Huberman model, with the components theory of transformational leadership developed by Bass and Avolio as a theoretical framework. The findings show that the leadership components of Umar bin Khattab were used in overcoming pessimistic situations due to Persian forces. Umar showed a leadership that was able to change the great vision of Muslims in facing Persian rule and had clear steps to realize it, was consistent in realizing dreams, was able to arouse and maintain the motivation of members by attending especially in difficult situations, and providing guidance to get out of difficulties. In the event that he cannot attend in person, long-distance communication is maintained. He appointed representatives who were believed to be able to transform leadership at lower levels. Umar succeeded in reviewing opportunities to improve the situation in ways that were outside the habits of his predecessors, one of which was by using an army of apostates who had repented. Thus Umar bin Khattab applied the four components of transformational leadership, namely idealized influence, inspirational motivation, individualized consideration, and intellectual stimulation.
Critical Success Factors Analysis Towards Development of Shariah Tourism Regency Kediri
Authors: Fatmawatie Naning
Published: June 2022

Pengembangan pariwisata syariah harus memenuhi persyaratan syariah, antara lain destinasi wisata, hotel atau restoran, akomodasi, transportasi, biro perjalanan, pemandu dan tempat ibadah. Critical Success Factor merupakan alat analisis dalam manajemen perusahaan yang menjadi pertimbangan penting bagi manajemen untuk mencapai visi dan misi perusahaan. Pengelolaan pengelolaan wisata syariah di daerah membutuhkan sistem pengelolaan yang profesional melalui Critical Success Factors.Tujuan dari penelitian ini adalah untuk mengetahui Critical Success Factors bagi pengembangan wisata syariah di Kabupaten Kediri dan pertumbuhan strategis keunggulan kompetitif wisata syariah di Kabupaten Kediri. Jenis penelitian ini adalah deskriptif kualitatif.Hasil penelitian ini menunjukkan bahwa: CSF pengembangan pariwisata di Kabupaten Kediri meliputi: budaya dari Kerajaan Joyoboyo mendominasi aspek sosial budaya Kabupaten Kediri, oleh karena itu perlu dilakukan studi yang melibatkan pemerintah daerah serta masyarakat setempat, mengingat budaya kerajaan Joyoboyo sangat lekat dengan sosial budaya. Perlu ada regulasi dari Kementerian Pariwisata tentang pengembangan wisata syariah di pemerintah daerah. Selain itu, semua destinasi wisata di Kabupaten Kediri belum memiliki sertifikasi halal. Strategi mewujudkan keunggulan daya saing pariwisata di Kabupaten Kediri, bahwa pengembangan destinasi wisata religi kunjungan ke makam pemuka agama berpotensi untuk dikembangkan wisata syariah. Untuk itu diperlukan sertifikasi halal dari MUI.
Creation and validation of a bilingual test to estimate aural and written vocabulary size
Authors: Aoiz Martín
Published: June 2022

Language learners’ vocabulary size is a reliable predictor of their success in a second language as it clearly correlates with better performances in the target language. Being precise in those estimations is paramount to plan language teaching. However, the instruments employed by previous studies for those estimations might present validity and reliability issues that affect their research sensitivity and accuracy.

This paper presents a step-by-step account of the creation of an aural and a written version of a bilingual vocabulary test. Test was delivered to 73 adult L1-Spanish students attending English classes. Their answers were analysed with Rasch model to determine the best performing items in the test so that the overall reliability of the instrument was enhanced.

The final version of the test presents high levels of reliability: .89 for the listening vocabulary test and .82 for the written vocabulary test. Furthermore, descriptive statistics confirm that recognizing the words in their aural form is more challenging than in their written form: participants got 10.80% fewer correct answers in the listening vocabulary test. This finding confirms the claim that aural and written vocabulary are two separate dimensions, and impacts on how vocabulary should be taught in L2 classrooms.
¿Influye el análisis de vídeo en la posición de los maestros en formación en contextos AICLE?
Authors: Díaz-Martín Cristina , Gómez Parra María Elena
Published: June 2022

Positioning theory helps to understand pre-service teachers’ performance and their professional identity. In the Content and Language Integrated Learning (CLIL) approach, studying teachers’ praxis from the positioning theory is relevant as integrating language and content is problematic for both in-service and pre-service teachers. Moreover, positioning theory could help teachers understand their teaching position. Video technology, as a valuable tool for teacher training, facilitates teachers’ analysis of their own teaching praxis and more importantly, it can help develop teaching awareness. However, scarce literature is found on how video-analysis from the positioning theory may benefit teachers in CLIL contexts. The objective of this paper is to analyse the influence of self video-analysis on pre-service teachers’ positions within CLIL settings. To conduct this research, pre-service teachers recorded and analysed a simulated CLIL lesson. Interviews were designed and administered to know the influence of video on participating teachers’ positions. Video supported pre-service teachers noticing their praxis and the meaning of CLIL while operating changes on their positions. Knowing the evolution of pre-service teachers’ positioning may contribute to, on the one hand, understanding professional identity and, on the other hand, to implement video-technology actions in pre-service programmes to support pre-service teachers’ noticing.
A qualitative examination of parents' views on the applicability of the project-based learning approach in science courses
Authors:   Department of Mathematics and Science Education, Education Faculty, Trakya University, Edirne, Turkey, Kiliç İsmail
Published: June 2022

This study was conducted to investigate the role of the parents of students in the science and technology lessons of the project-based teaching approach. The research was carried out through a case study, one of the qualitative research methods. The data of the study were obtained from semi-structured interviews with 24 students' parents. As a result of the research, it was understood that the parents of the students saw the project as a study aimed at increasing the students' hand skills, thinking skills, and productivity to prepare something new. As a result, it was seen that after the project assignment was given by the teachers, the parents were involved in the process to help their children complete the projects. At the end of the process of doing the project assignments, it was concluded that the parents received informal training, both in one-on-one interviews with the parents who helped their children and in the observations made during the project exhibitions at the school. This situation was important in terms of the informal education of parents. It was also determined that the parents helped their children during the setup and presentation of the project and that they wanted to complete it when wrong or incomplete explanations were made. It was observed that as the contribution of the parents increased during the completion of the projects, the role of the students in the projects decreased and they did not take responsibility. It was concluded that the students thought of family aids as a tool to achieve higher academic success than the project assignments, and therefore the homework deviated from its purpose.
La arquitectura entre el Arte y la Técnica. Aportes para una revisión historiográfica
Authors: Bellot Rodolfo , Fiscarelli Diego
Published: June 2022

La producción arquitectónica expone particulares conceptualizaciones a partir de la tensión arte│técnica. Los avances tecnológicos presentan objetos con profundos cambios en su naturaleza, tanto en la función como en la forma. En este sentido, este trabajo propone una renovada reflexión sobre la relación entre arte y técnica en arquitectura, que pretende reconocer los recientes criterios de actuación y construir un posible estado de situación. Para esto, comienza por definir ambos conceptos y sus orígenes, para luego explicitar momentos de estrecha relación, signados por procesos de continuidad o ruptura. En términos metodológicos, se recurre a una discusión bibliográfica, que incluye una cuidadosa selección de exponentes teóricos, se busca comprender la compleja red de atracciones y desencuentros, con el objeto de habilitar una discusión aun no saldada, que incluso ha intensificado su debate en los últimos años.
Online Learning Quality, Satisfaction, and Word-of-Mouth Promotion
Authors:   Maranatha Christian University, Indonesia, Mikhael Mikhael , Carolin Yohana , Nathania Yohanna , Hadianto Bram
Published: June 2022

This study aimed to verify and analyze the two influences. The first was the effect of online learning quality (OLQ) on student satisfaction and word-of-mouth (WOM) promotion. The second was the impact of student satisfaction on WOM promotion. Then, we used the population of 137 students taking online classes during the COVID-19 pandemic at Indonesia's Interkultural Edukasi Partner (IEP) in Bandung to support this intention. Furthermore, we applied the Slovin formula with a 5% border of fault to obtain a sample size of 103. After getting it, the samples were taken by simple random sampling. Unfortunately, only 45 students responded by filling out the questionnaire distributed. As a result, this study utilized the structural equation model based on variance to examine the proposed hypotheses. After testing and discussing them, this research concluded that OLQ positively influenced student satisfaction, but OLQ did not. Besides, student satisfaction positively affected this promotion.
Eritema necrolítico migratorio como manifestación de tumor neuroendocrino de páncreas. Valoración clínico-radiológica
Authors: Dulcich Gonzalo , Mestas Nuñez Marcos Alejandro , Gentile Ernestina Maria Jose
Published: June 2022

El glucagonoma es un tumor neuroendocrino de muy baja incidencia, se estima 1 caso cada 20 millones de personas por año. Típicamente, se manifiesta con un síndrome clínico que incluye una dermatosis característica denominada eritema necrolítico migratorio (ENM). Presentamos el caso de un varón de 60 años con ENM como presentación inicial de un tumor pancreático y los hallazgos por imágenes del mismo. Resaltamos la importancia de reconocer las características clínicas del ENM y el rol de los diferentes métodos por imágenes para un diagnóstico precoz y correcto manejo de estos tumores pancreáticos.
Variantes en el número de copias y consanguinidad parental en neonatos de altura con anomalías congénitas en Perú
Authors: Abarca Barriga Hugo Hernán , Chavesta Velásquez Felix , Barletta Carrillo Claudia , Paucarmayta Tacuri Abel , Bazán Hurtado Margaret , Vásquez Loarte Tania , Ordoñez Rondón Luis , Ordoñez Linares Marco , Rondón Abuhadba Evelina Andrea
Published: June 2022

Introducción. Las variantes en el número de copias son un tipo de cambios en el genoma provocan anomalías congénitas.

Objetivo. Determinar las variantes en el número de copias y el grado de consanguinidad parental en neonatos con síndromes malformativos o una anomalía congénita mayor asociado a dismorfia facial o hipotonía.

Material y métodos. Se realizó el análisis cromosómico por micromatrices a 60 neonatos con anomalías congénitas  evaluados en los Hospitales Antonio Lorena y Regional de Cusco.

Resultados. Del total de pacientes estudiados, el 70% tuvo un resultado anómalo; de los cuales en el 14,2% de los recién nacidos se encontraron variantes en el número de copias patogénicas o probablemente patogénicas asociadas o no a regiones de homocigosidad que tuvieron relación con las anomalías congénitas descritas. En el 48,3% de los recién se encontró regiones de homocigosidad mayores a 0,5% (coeficiente de endogamia superior a 1/64). Por otro lado, encontramos cinco variantes en el número de copias de patogenicidad desconocida que no se han descrito anteriormente y podrían estar relacionadas con el fenotipo.

Conclusiones. Nuestra tasa de detección de las variantes en el número de copias está en relación con los reportes internacionales previos. Sin embargo, el porcentaje de neonatos con consanguinidad parental se encuentra por encima de lo reportado previamente, siendo superior a otras regiones de Sudamerica. Este es el primer reporte en el Perú, y es pionero en Latinoamérica al utilizar el análisis cromosómico por micromatrices en esta cohorte específica de pacientes.
COVIDx-US: An Open-Access Benchmark Dataset of Ultrasound Imaging Data for AI-Driven COVID-19 Analytics
Authors: Ebadi Ashkan , Xi Pengcheng , MacLean Alexander , Florea Adrian , Tremblay Stéphane , Kohli Sonny , Wong Alexander
Published: June 2022

Background: The Coronavirus Disease 2019 (COVID-19) pandemic continues to have a devastating effect on the health and well-being of the global population. Apart from the global health crises, the pandemic has also caused significant economic and financial difficulties and socio-physiological implications. Effective screening, triage, treatment planning, and prognostication of outcome play a key role in controlling the pandemic. Recent studies have highlighted the role of point-of-care ultrasound imaging for COVID-19 screening and prognosis, particularly given that it is non-invasive, globally available, and easy-to-sanitize. COVIDx-US Dataset: Motivated by these attributes and the promise of artificial intelligence tools to aid clinicians, we introduce COVIDx-US, an open-access benchmark dataset of COVID-19 related ultrasound imaging data. The COVIDx-US dataset was curated from multiple data sources and its current version, i.e., v1.5., consists of 173 ultrasound videos and 21,570 processed images across 147 patients with COVID-19 infection, non-COVID-19 infection, other lung diseases/conditions, as well as normal control cases. Conclusions: The COVIDx-US dataset was released as part of a large open-source initiative, the COVID-Net initiative, and will be continuously growing, as more data sources become available. To the best of the authors’ knowledge, COVIDx-US is the first and largest open-access fully-curated benchmark lung ultrasound imaging dataset that contains a standardized and unified lung ultrasound score per video file, providing better interpretation while enabling other research avenues such as severity assessment. In addition, the dataset is reproducible, easy-to-use, and easy-to-scale thanks to the well-documented modular design.
Altered Amplitude of Low-Frequency Fluctuations and Degree Centrality in Patients with Acute Subjective Tinnitus: A Resting-State Functional Magnetic Resonance Imaging Study
Authors: Chen Jianfei , Fan Li , Cai Guoqian , Hu Bing , Xiong Yuanping , Zhang Zhiyuan
Published: June 2022

Background: The difference in spontaneous brain activity between acute subjective tinnitus patients (with or without hearing loss) and control participants was explored using the amplitude of low-frequency fluctuations and degree centrality methods through resting-state functional magnetic resonance imaging. The study aimed to provide an objective basis for clinical diagnosis and pathogenesis of patients with acute subjective tinnitus. Methods: Fourteen acute subjective tinnitus (AST) patients with hearing loss (AST-HL), 6 AST patients with no hearing loss (AST-NHL), and 14 healthy controls (HCs) with age, sex, and education status matched were recruited for this study. Resting-state functional magnetic resonance imaging (fMRI) examinations were performed in a resting state and the amplitude of low-frequency fluctuations (ALFF) and degree centrality (DC) values of each group were acquired. Statistical analysis was performed to assess the ALFF and DC values of different brain areas of the participants (AST-HL and AST-NHL were compared with HCs, but AST-HL and AST-NHL were not). Results: Patients with acute subjective tinnitus and hearing loss showed a significantly increased amplitude of low-frequency fluctuation values in the left middle temporal gyrus and bilateral frontal gyrus/marginal lobe/cingulate gyrus but a decreased amplitude of low-frequency fluctuations values in the bilateral superior temporal gyrus/anterior cerebellar lobe in comparison with healthy controls. The amplitude of low-frequency fluctuation values of patients with acute subjective tinnitus and hearing loss in the right posterior lobe of the cerebellum, bilateral temporal gyrus, bilateral lenticular nucleus, bilateral frontal gyrus, right inferior occipital gyrus, were higher, but were significantly lower in the bilateral anterior lobe of cerebellum/superior temporal gyrus and left posterior cerebellar lobe as compared with those of healthy controls. Degree centrality values in the healthy controls group were increased in the right superior marginal gyrus and decreased in the right thalamus in patients with acute subjective tinnitus and hearing loss, while patients with acute subjective tinnitus with no hearing loss presented significantly higher degree centrality values in the left frontal lobe and lower degree centrality values in the left center rear return. Conclusions: Aberrant amplitude of low-frequency fluctuations and values exist in various brain regions, indicating abnormal spontaneous brain activity in both acute subjective tinnitus and hearing loss and acute subjective tinnitus no hearing loss patients. The pathogenesis of acute subjective tinnitus may be related to abnormalities in both the auditory cortex and nonauditory cortex. These findings provide more evidence to help clarify the neuronal symptoms of acute subjective tinnitus patients.
Glymphatic System Function in Patients with Transient Global Amnesia
Authors: Lee Dong Ah , Park Bong Soo , Park Sihyung , Lee Yoo Jin , Ko Junghae , Park Kang Min
Published: June 2022

Background: The purpose of this study was to examine glymphatic system function in patients with transient global amnesia (TGA), as well as to conduct a recurrence analysis. Methods: We enrolled patients with TGA and healthy controls from our hospital retrospectively. The patients and healthy controls were all scanned with the same 3T scanner, which included diffusion tensor imaging (DTI). We investigated the function of the glymphatic system using DTI analysis along the perivascular space (DTI-ALPS). The ALPS index was compared between patients with TGA and healthy controls, as well as between patients who had recurrent TGA events and those who had only a single TGA event. Results: Seventy-two patients with TGA and 53 healthy controls were enrolled. Sixty-five patients with TGA had a single TGA event, while seven patients had recurrent TGA events. The ALPS index did not differ significantly between patients with TGA and healthy controls (1.665 vs. 1.618, p = 0.436). The ALPS index, on the other hand, varied significantly according to recurrence in patients with TGA. The ALPS index was significantly higher in patients with recurrent TGA events compared to those with a single event (1.928 vs. 1.636, p = 0.049). Conclusions: We investigated the glymphatic system function in patients with TGA compared to healthy controls for the first time using the DTI-ALPS method. We discovered that these groups did not differ in terms of glymphatic system function. However, glymphatic system function in patients with TGA may differ according to recurrence. Additional research is required to substantiate these findings.
Advances in chondroitinase delivery for spinal cord repair
Authors: Wei Yuting , Andrews Melissa R.
Published: June 2022

Chondroitin sulfate proteoglycans (CSPGs) present a formidable barrier to regrowing axons following spinal cord injury. CSPGs are secreted in response to injury and their glycosaminoglycan (GAG) side chains present steric hindrance preventing the growth of axons through the lesion site. The enzyme chondroitinase has been proven effective at reducing the CSPG GAG chains, however, there are issues with direct administration of the enzyme specifically due to its limited timeframe of activity. In this perspective article, we discuss the evolution of chondroitinase-based therapy in spinal cord injury as well as up-to-date advances on this critical therapeutic. We describe the success and the limitations around use of the bacterial enzyme namely issues around thermostability. We then discuss current efforts to improve delivery of chondroitinase with a push towards gene therapy, namely through the use of lentiviral and adeno-associated viral vectors, including the temporal modulation of its expression and activity. As a chondroitinase therapy for spinal cord injury inches nearer to the clinic, the drive towards an optimised delivery platform is currently underway.
Aortic Valve Replacement in the Failing Left Ventricle: Worthwhile?
Authors: Kalyanasundaram Asanish , Vinholo Thais Faggion , Zafar Mohammad A. , Anis Osama , Charilaou Paris , Ziganshin Bulat , Elefteriades John A.
Published: June 2022

Purpose: According to the 2020 American College of Cardiology/American Heart Association guidelines, the aortic valve should be replaced in the setting of severe aortic stenosis or regurgitation, independent of left ventricular function (even for EF <55%). However, in clinical practice, especially in a very low EF range, surgeons may avoid surgical aortic valve replacement (SAVR) because of concern over operative risk. This study examines outcomes of patients with EF ≤35% undergoing SAVR. Methods: From 2004 to 2019, 895 patients underwent SAVR for aortic stenosis (AS) and/or regurgitation (AR) by a single surgeon at our institution. From among these, 40 patients (4.47%) had an ejection fraction (EF) of 35% or less, forming the study group. Intra-aortic balloon pump was placed intraoperatively prophylactically pre-bypass in 18 out of the 40. Preoperative and post-operative echocardiograms were compared to determine changes in ejection fraction. Mid-term survival was assessed. Results: 16 patients presented with AS, 20 with AR, and 4 with a combination of AS and AR. Hospital survival was 97.5% (one patient death). The average ejection fraction progressively improved over time from 26% initially to 46% mid-term with mean follow-up of 43 months (0.1–140.7). Remarkably, five-year survival was comparable between the study group and an age- and gender-matched general population (p = 0.834). Downward trends in LV end-diastolic diameter and end-systolic diameter were seen. The former achieved statistical significance (6.0 cm to 5.3 cm; p = 0.0046), while the latter fell slightly short (4.8 cm to 4.1 cm; p = 0.056). Patients in whom an IABP was used had lower EFs than those without IABP (range 10–35, mean 23% vs. 15–35%, mean 27.6%). The EFs of the three subgroups improved significantly postoperatively (p < 0.001 for AS, p = 0.002 for AR, and p = 0.046 for AS and AR). Conclusions: Surgical AVR can be done safely in patients with a failing LV with EF ≤35%. Significant improvements in the ejection fraction are seen over time. We believe there is a role for prophylactic pre-bypass IABP. Five-year survival is normalized. Surgeons should not hesitate to perform AVR in these highly jeopardized patients.
Systolic Pulmonary Artery Pressure and Cardiovascular Biomarkers—New Non-Invasive Ways to Detect Pulmonary Hypertension in Patients with Severe Aortic Valve Stenosis Undergoing TAVR?
Authors: Boxhammer Elke , Köller Clara , Paar Vera , Fejzic Dzeneta , Rezar Richard , Reiter Christian , Kammler Jürgen , Kellermair Jörg , Hammerer Matthias , Blessberger Hermann , Steinwender Clemens , Hoppe Uta C. , Lichtenauer Michael
Published: June 2022

Background: Patients with severe aortic valve stenosis (AS) frequently present with pulmonary hypertension (PH). The gold standard for detection of pulmonary hypertension is right heart catheterization, which is not routinely performed as a preoperative standard in cardiology centers today, neither before surgical valve replacement nor before transcatheter aortic valve replacement (TAVR) procedure. Echocardiographic determination of systolic pulmonary artery pressure (sPAP) provides an opportunity to assess the presence or absence of PH. The aim of the present study was to investigate the extent to which plasma levels of common cardiovascular biomarkers behave in patients with severe AS and an sPAP <40 mmHg in comparison to patients with an sPAP ≥40 mmHg. Methods: 179 patients with echocardiographic evidence of severe AS before TAVR procedure were divided into 2 groups based on sPAP. An sPAP of 40 mmHg was considered the cut-off value, with absence of PH defined by an sPAP <40 mmHg (n = 82) and presence of PH defined by an sPAP ≥40 mmHg (n = 97). Directly before TAVR, a blood sample was drawn from each patient, and plasma concentrations of the cardiovascular biomarkers Soluble Suppression of Tumorigenicity-2 (sST2), Growth/Differentiation of Factor-15 (GDF-15), Heart-Type Fatty-Acid Binding Protein (H-FABP), Insulin Like Growth Factor Binding Protein 2 (IGF-BP2), Soluble Urokinase-Type Plasminogen Activator Receptor (suPAR), Brain Natriuretic Peptide (BNP) and Cardiac Troponin I (cTnI) were determined. Results: Patients with an sPAP ≥40 mmHg had significantly higher sST2 (p = 0.010), GDF-15 (p = 0.005), IGF-BP2 (p = 0.029), suPAR (p = 0.018), BNP (p < 0.001) and cTnI (p = 0.039) plasma levels. Only for H-FABP (p = 0.069), no significant differences were discernible between the two groups. In addition, cut-off values were calculated to predict an sPAP ≥40 mmHg. Significant results were shown with 16045.84 pg/mL for sST2 (p = 0.010), with 1117.54 pg/mL for GDF-15 (p = 0.005), with 107028.43 pg/mL for IGF-BP2 (p = 0.029), with 3782.84 pg/mL for suPAR (p = 0.018), with 2248.00 pg/mL for BNP (p < 0.001) and with 20.50 pg/mL for cTnI (p = 0.002). Conclusions: sPAP as an echocardiographic parameter in combination with supplementary use of cardiovascular biomarkers presented here have the potential to provide more detailed information about the presence or absence of PH in a non-invasive way.
Bagaimana Dampak Kebijakan Insentif PPnBM Ditanggung Pemerintah Terhadap Kinerja Industri Kendaraan Bermotor? Bukti Dari Indonesia
Authors: Pratama Rheza Afrian , Rezki Jahen Fachrul
Published: June 2022

This study discusses the impact of the Government borne PPnBM incentive policy for the motor vehicle industry which was carried out during the Covid-19 pandemic by analyzing motor vehicle sales data for 2020-2021. This study is a quantitative study that measures the impact of policies using the difference-in-difference (DiD) method. From the results of research using the DiD method, it was found that in the short term the PPnBM incentive policy had a positive impact on increasing vehicle sales by 46.1%. Meanwhile, in the long-term evaluation, it was found that the PPnBM incentive policy did not have a significant impact on motor vehicle sales in Indonesia as long as the policy was implemented.
Studi ini membahas mengenai dampak kebijakan insentif PPnBM Ditanggung Pemerintah untuk industri kendaraan bermotor yang dijalankan selama pandemi Covid-19 dengan menganalisis data penjualan kendaraan bermotor selama tahun 2020-2021. Penelitian ini adalah penelitian kuantitatif yang mengukur dampak kebijakan dengan menggunakan metode difference-in-difference (DiD). Dari hasil penelitian dengan menggunakan metode DiD ditemukan bahwa dalam jangka pendek kebijakan insentif PPnBM memberikan dampak positif pada peningkatan penjualan kendaraan sebesar 46,1%. Sementara dalam evaluasi jangka panjang ditemukan bahwa kebijakan insentif PPnBM justru tidak memberikan dampak signifikan pada penjualan kendaraan bermotor di Indonesia selama kebijakan dilaksanakan.
Pengaruh Kepercayaan Kepada Pemerintah Terhadap Kepatuhan Pajak Dengan Persepsi Keadilan Pajak Sebagai Variabel Intervening
Authors: Zainudin Fardan Ma'ruf , Nugroho Rahadi , Muamarah Hanik Susilawati
Published: June 2022

This study aims to examine the role of tax justice perception in mediating the effect of trust in government on tax compliance. The research was conducted using quantitative methods. The type of data used in this study is primary data obtained directly from respondent answers to the questionnaires that have been distributed. The population in this study is WPOP Non Karyawan in Indonesia. The sampling technique used in this study is non probability sampling with convenience sampling technique. The research sample used in this study was 385 taxpayers. The results show that trust in government had a positive effect on perception of tax justice and tax compliance, perception of tax justice had a positive effect on tax compliance, and perception of tax justice mediates between trust in government and tax compliance.
Penelitian ini bertujuan untuk menguji peran persepsi keadilan pajak dalam memediasi pengaruh kepercayaan kepada pemerintah terhadap kepatuhan pajak. Penelitian dilakukan dengan metode kuantitatif. Jenis data yang digunakan dalam penelitian ini adalah data primer yang diperoleh langsung dari jawaban responden atas kuesioner yang telah dibagikan. Populasi dalam penelitian ini adalah WPOP Non Karyawan di Indonesia. Teknik pengambilan sampel yang digunakan dalam penelitian ini adalah non probability sampling dengan teknik convenience sampling. Sampel penelitian yang digunakan dalam penelitian ini sebanyak 385 Wajib Pajak. Hasil Penelitian menunjukkan bahwa kepercayaan kepada pemerintah berpengaruh positif terhadap persepsi keadilan pajak dan kepatuhan pajak, persepsi keadilan pajak berpengaruh positif terhadap kepatuhan pajak, dan persepsi keadilan pajak menjadi mediasi antara kepercayaan kepada pemerintah terhadap kepatuhan pajak.
Property Taxation: Transformational Changes in the Digital Era and Impact of the COVID-19 Pandemic
Authors:   St. Petersburg State University, St. Petersburg 191123, Russian Fedetation, Timchenko Elena N. , Pogorletsky Alexander I. ,   St. Petersburg State University, St. Petersburg 191123, Russian Fedetation
Published: June 2022

The timeliness of this research is determined by the large-scale changes taking place in the world economy under the influence of digitalization, which accelerated during the COVID-19 pandemic. These processes affect the direction of transformational changes in property taxation. The object of the study is property taxation in the context of the proliferation of various forms of digital assets, which are virtual property. The purpose of the article is to find correlations between digitalization, the need to limit overconsumption, which has increased during the pandemic of a new coronavirus infection, and the prospects for changes in property taxation. The possibilities of state tax regulation and interstate cooperation in the context of property taxation are considered. The prospects for expanding the effect of property taxation to the virtual spaces of the metauniverse are highlighted. The article uses general scientific research methods such as analysis, synthesis, generalization and analogy, and contains historical and cross-country comparison. The information base is formed on the basis of data from international organizations, consulting, analytical and research companies, as well as government agencies. As a result of the research, the hypothesis was confirmed that the current changes in the global economy require transformation of approaches to property taxation both at the state and international levels, taking into account the expansion of modern technology capabilities and the need to limit excessive consumption. Recommendations have been formulated to expand the scope of property taxation in virtual spaces and to increase the level of the wealth taxation of the wealthiest segments of the population possessing virtual forms of ownership.
Providing Incentives for Intellectual Labor through Tax Policy in Belarus
Authors:   Belarusian State Economic University, Minsk 220070, Republic of Belarus, Kireyeva Alena , Pinskaya Milyausha R. ,   Financial Research Institute, Moscow 127006, Russian Federation
Published: June 2022

This paper discusses the idea of providing tax incentives for scholars and researchers as a necessary factor in the formation of innovative environment. The research aims at formulating proposals for increasing income from intellectual work through tax incentives based on the analysis of scientific research context and existing tax regime for Belorussian researchers. It is argued that the quantity and quality of intellectual labor depend on the tax regime applied. Academic science environment in Belarus is analyzed and the mechanism of taxation of researchers’ income is discussed in its context. The structure of current costs for research and development is demonstrated. Authors show the insufficiency of the existing tax incentives for intellectual labor, including research grants. The analysis is focused on the mechanism of taxation and collection of social insurance contributions from the remuneration of members of temporary research teams. The authors propose to introduce special tax rules for research income from research activities, and consider these possible rules in detail. The theoretical framework of this article is based on the research of national and foreign scholars in the fields of taxation theory, taxation of individuals, and intellectual capital.
Sentiment analysis for identifying the political inflection point in Putin’s war
Authors: Cetera Wiesław , Żołnierski, Aleksander , Jaruga Dariusz , Celinski Piotr , Grzegorek Jan
Published: June 2022

  

Sentiment analysis is a tool used in many areas (marketing, management, sociology) and its effectiveness depends on the quality of sources and the volume of data gathered. The authors present procedures that allow the collection of large volumes of text data and the processing thereof, the result of which is a quick (practically in real time) assessment of emotions and their changes. In the example analysis Russian sources are given (in the Russian language, creating a system of media monopolised by the authorities). The analysis was between week 1 and 17 of 2022 - before and during the conflict between Russia and Ukraine. The results obtained, trends of changes in sentiments pertain to Presidents Joe Biden, Andrzej Duda, Aleksandr Lukashenko, Emmanuel Macron, Volodymyr Zelensky and Vladimir Putin - the results are emotionally charged figures of presidents created for the internal purposes of Russia and provide significant information for analysts of the ongoing conflict. Obtaining similar results without the use of information technology is practically impossible. Sentiment analysis of large resources makes it possible to detect the change dynamics that are difficult for a human being to capture (a person analysing source materials). Concurrently, the cost and time of obtaining results recommends the described method as supporting analytical work. 