bluuebunny/crossref_metadata_2025 huggingface dataset:
Graves’ disease with spontaneous resolution following ocrelizumab in primary progressive multiple sclerosis
Authors: Duarte Diana Borges , Silva Ana Martins da , Freitas Claudia , Cardoso Helena
Published: September 2021

Objectives. Immune reconstitution therapies (IRT), which include antibody-based cell-depleting therapies targeting CD52+ (alemtuzumab) or CD20+ (rituximab, ocrelizumab) leukocytes, are approved for the treatment of multiple sclerosis. Thyroid autoimmunity is a common adverse effect of alemtuzumab treatment, Graves’ disease (GD) being the most prevalent manifestation. To date, thyroid autoimmunity events have not been reported with CD20-targeting monoclonal antibodies.

Case Report. A 59-year-old woman with primary progressive multiple sclerosis with no prior personal history of thyroid disease or autoimmunity, was diagnosed with GD 6 months following the first ocrelizumab infusion. She was asymptomatic and had no signs of ophthalmopathy. Due to the temporal association of GD diagnosis with ocrelizumab infusion, absence of symptoms and our experience with alemtuzumab-induced GD, we decided for an active surveillance strategy and antithyroid drugs were not started. She underwent spontaneous resolution of hyperthyroidism with thyroid-stimulating hormone (TSH) receptor antibodies (TRAb) negativity and a mild and transitory period of subclinical hypothyroidism, while she continued the biannually ocrelizumab administration schedule. To present date, she has maintained close clinical and biochemical surveillance with normal TSH, free thyroxine (fT4) and free triiodothyronine (fT3) levels and undetectable TRAb.

Conclusions. This is the first case of GD reported after ocrelizumab administration. The timing, onset and course of this case is similar to alemtuzumab-induced GD, usually interpreted as an “immune reconstitution syndrome”; however, ocrelizumab cell count depletion is inferior in severity, cell population affected and duration of depletion. This case highlights the importance of pre-screening and follow-up with thyroid function tests in patients treated with ocrelizumab. As a novel therapeutic antibody, further investigation is required to unravel the causes of thyroid autoimmunity.
Budget behaviour and cultural contingencies: case study in a Tunisian company
Authors: Dakhli Anissa
Published: September 2021

Background

Budgetary participation has a positive impact on a variety of emotional and behavioural responses. However, the review of empirical studies conducted in Tunisia reveals a low participation rate among operating managers in the budget control systems of their companies.

Research aims

The purpose of this study is to understand, from a contingency perspective, the practices of budgetary participation in Tunisian companies. It aims to explore forms of budgetary participation practised by Tunisian companies and examine to what extent Tunisian cultural variables explain these budgetary behaviours.

Methodology

A qualitative methodology based on a single case study was used. The data collected were the subject of a thematic content analysis.

Findings

The results show that the Tunisian companies have serious difficulties engaging in budgetary participation. Several factors hinder the implementation and operation of this budgetary practice. The primary factors include personality variables that, although interact with cultural values rooted in Tunisian society, create a psychological inconsistency between the ideal environment for the development and success of a participative approach and the environment of the Tunisian company.
About Sacubitril/Valsartan: A Clinically-Oriented Primer for Internists
Authors: Casian Mihnea , Munteanu Alice Elena
Published: September 2021

The medical therapy of heart failure (HF) has been traditionally based on inhibiting the main pathophysiologic mechanisms: the adrenergic and renin-angiotensin-aldosterone systems. Introducing the therapeutical triad of beta-blockers, angiotensin converting enzyme inhibitors and mineralocorticoid receptor antagonists in the treatment of HF patients almost 40 years ago marked an important step since they were not only addressing the symptoms of HF, but also the prognosis and life- expectancy of these patients. Although many discoveries have been made in the past years, no other therapeutic class was able to increase survival among HF patients, until recently, when th SA e benefits of modulating the natriuretic peptide system were brought to the attention of the scientific community. Increasing the levels of natriuretic peptides with Sacubitril/ Valsartan (SV) led to several benefits for the reduced ejection fraction HF population, including less long and short term complications, increased survival and a reduced symptom burden. As this article is being written, it is estimated that more than 2.8 million patients are being treated with SV(1). Therefore, SV is an important and validated therapy for HF patients and internists should be aware of its indications, benefits and management in clinical practice.
Protection of power transformers against the effect of magnetic storms
Authors: Mayer Daniel
Published: September 2021

In the operation of large-scale power systems for the long-distance transmission of large amounts of electricity, a number of cases have been reported in which anomalies in the Earth’s magnetosphere, referred to as geomagnetic storms, have caused a severe system collapse. Changes in the geomagnetic field cause a semi-saturating phenomenon, in which the high-voltage lines and especially the high-voltage windings of the power transformers of the system are overloaded with current and subsequently also thermally. The present article briefly explains the physical nature of magnetic storms and then describes a new device that either eliminates the possibility of a step-down power transformer accident or significantly reduces its effects on the system. The essence of this device are frequency filters, which are connected in parallel to the high-voltage windings of power transformers. At the beginning of a geomagnetic storm, the frequency filter is automatically connected to the system and is automatically disconnected when it subsides. The operation of frequency filters does not require human intervention, acquisition and operating costs are low and their integration into existing power systems is easy.
THE ROLE OF TELEMEDICINE IN TRAINING OF SCIENTIFIC-PEDAGOGICAL AND PROFESSIONAL MEDICAL STAFF
Authors:   Department of General Surgery № 1, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan, GULOV M.K. , MUKHABBATOV D.K. ,   Department of General Surgery № 1, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan, KOBILOV K.K. ,   Department of Operative Surgery and Topographic Anatomy, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan, ALI-ZADE S.G. ,   Department of Surgical Diseases № 1, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan
Published: September 2021

Nowadays, telemedicine services are widely used throughout the world. Various types of telemedicine services, such as the storage and transmission of real-time information, remote monitoring or self-control can be applied in the fields of education, health and management, disease screening and disaster risk management worldwide. Telemedicine can play a big role in conducting medical research, as well as in the field of training scientific personnel, allowing remotely collaborate with scientific and clinical institutions and gain access to expensive remote equipment. In this context, it is considered appropriate to develop and apply such innovative ideas as online computing models in telehealth applications; simplified software and hardware interfaces, programs for modelling; portable telepresence systems; artificial intelligence applications that are especially relevant in cases where simulated patients cannot replace real ones; and development of a large number of application simulators. Keywords: Telemedicine, technology, telecommunications, innovation.
CLINICAL AND LABORATORY FEATURES OF ENDOGENOUS INTOXICATION SYNDROME IN CHILDREN UNDER 3 YEARS WITH PNEUMONIA
Authors:   Department of Morphology, Faculty of Medicine, Tajik National University, Dushanbe, Republic of Tajikistan, ABDURAKHIMOV R.M. , VOKHIDOV A. ,   «Istiklol» Health Complex, Dushanbe, Republic of Tajikistan
Published: September 2021

Objective: To study the clinical features of the course and the dynamics of some haematological indices in endogenous intoxication syndrome in children under 3 years of age suffering from pneumonia. Methods: There were 80 children under surveillance, of which 60 were pneumonia patients (main group), and 20 healthy children (control group). Laboratory survey included determining levels of leukocyte index of intoxication (LII), lactic and uric acids. The respiratory failure (RF) I is noted in 51.6%, RF II in 34.2% and RF III in 14.2% of cases. Results: Clinically and radiologically, 60.5% of children were diagnosed with bilateral processes in lungs, and in 39.5% the unilateral process. Signs of endogenous intoxication were: hyperhidrosis (59.4%), acrocyanosis (46.6%), perioral cyanosis (55.5%), mottled skin integument (49.2%), pronounced subcutaneous venous network (48.2%). The LII rate in the acute period had a strong tendency towards an increase of up to 5 days, with a gradual reduction to normal reference values by the end of the first week. It was found that high levels of lactic and uric acids were closely correlated with hypoxia. For example, in RF I, II and III levels of lactic acid were 1.3±0.1, 1.9±0.2 and 2.61±0.25 respectively. Children with RF III have degrees of lactic acid concentration that was statistically significant (p<0.001) higher than in the control group. Conclusions: Lactic and uric acid levels depend on the degree of RF and can indicate the severity of endogenous intoxication syndrome. The reduction of LII indices below 3.0 by the end of the first week of the disease, maybe a sign of a favorable outcome. Keywords: Pneumonia, respiratory failure, endogenous intoxication, leukocyte index of intoxication, lactic acid, uric acid.
FEATURES OF CLINICAL MANIFESTATIONS, CELLULAR AND HUMORAL IMMUNITY OF NEWBORNS WITH INTRAUTERINE MIXED INFECTIONS
Authors:   Department of Pediatric Diseases № 2, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan, YUSUPOVA M.A. , ISMOILOV K.I. ,   Department of Pediatric Diseases № 2, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan
Published: September 2021

Objective: To study the features of clinical manifestations, cellular and humoral immunity of newborns with intrauterine mixed infections (IUMI). Methods: A comprehensive survey of 45 infants with IUMI was carried out. Depending on the classification of IUMI they were divided into 3 main groups: group I – 24 patients (53%) with the viral-bacterial association, group II – 12 patients (27%) with the viral-viral association, and group III – 9 patients (20%) with the viral-parasitic association. The control group consisted of 10 newborns born from uninfected, somatically healthy mothers. Diagnosis of IUMI was based on the detection of specific antibodies of the IgA, IgG and IgM classes, as well as phagocytic activity and phagocytic index of leukocytes. In addition, general clinical, biochemical, bacteriological and instrumental research methods have been conducted. Results: The blood serum IgA and IgM indices in patients of the main group were significantly higher, and the mean IgG values were lower compared to the control group. Analysis of cellular immunity parameters in the main group showed a decrease in the number of mature T-lymphocytes (CD3), B-lymphocytes (CD20), the number of T-helpers and cells that produce IL-2 in the peripheral blood, compared with the control group. In the main group, there was also an increase in the number of apoptosis cells (CD95), cells with high cytotoxic activity (CD25, CD71) and the percentage of natural killer cells (CD16). A decrease in the phagocytic activity and phagocytic index of neutrophils was recorded, which indicates the insufficiency of the nonspecific component of immunity. Conclusions: In newborns, various changes were found both on the part of specific and nonspecific components of immunity. This indicates the development of secondary immunodeficiency in this category of patients and makes it necessary to add to the main treatment of immune corrective therapy. Keywords: Congenital infections, mixed intrauterine infections, TORCH syndrome, opportunistic infections, secondary immunodeficiency.
RESULTS OF THE USE OF MINIMALLY INVASIVE TECHNOLOGIES IN THE SURGICAL TREATMENT OF HEPATIC ECHINOCOCCOSIS AND ITS COMPLICATIONS
Authors:   Department of Surgical Diseases № 1, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan, KURBONOV K.M. , AZIZZODA Z.A. ,   Department of Surgical Diseases № 1, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan, EFANOV M.G. ,   Department of Hepatopancreatobiliary Surgery, Loginov Moscow Clinical Scientific Center, Moscow, Russian Federation, RUZIBOYZOD K.R. ,   Department of Surgical Diseases № 1, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan
Published: September 2021

Objective: To evaluate the results of using minimally invasive technologies in the surgical treatment of hepatic echinococcosis (HE) and its complications. Methods: The results of examination and surgical treatment of 165 patients with HE and its complications using minimally invasive technologies are presented. Results: 77 patients with uncomplicated HE underwent: open echinococcectomy (EE) from various mini-accesses (n=37), laparoscopic EE (n=30), PAIR technology (n=6), hepatic resection using the da Vinci S robotic complex (n=4). In patients with suppurated hydatid cysts (n=49) a combination of percutaneous cyst puncture with laparoscopic (4) and open (5) EE; PAIR technology (5) and laparoscopic EE (35) were performed. All 39 patients with intrabiliary rupture of hydatid cysts underwent two-stage interventions: percutaneous transhepatic choledochostomy followed by laparoscopic (7) and traditional (4) EE; endoscopic papillosphincterotomy (EPST) followed by open EE (9); laparoscopic choledochostomy followed by open EE (3); EPST followed by laparoscopic total (2) and subtotal (14) pericystectomy. Postoperative complications were noted in 29 (17.5%), relapses of the disease – in 12 (10.9%), lethal outcome – in 1 (0.6%) cases. Based on the analysis of the study, an algorithm for choosing the method of surgical treatment for HE and its complications was developed. Conclusions: The use of minimally invasive technology for hepatic echinococcosis can improve surgical treatment outcomes. Keywords: Hepatic echinococcosis, diagnosis , minimally invasive technologies, surgical treatment, treatment results.
MYCOBACTERIOSIS: A REVIEW OF EVIDENCE-BASED CLINICAL MANIFESTATIONS AMONG HUMANS
Authors:   Regional Office of Rospotrebnadzor for the Republic of Tatarstan, Kazan, Russian Federation, PETROVA F.S. , PETROV I.V. ,   Department of Fundamental Medicine, Mari State University, Yoshkar-Ola, Russian Federation, AMIROVA T.KH. ,   Department of Fundamental Medicine, Mari State University, Yoshkar-Ola, Russian Federation, PETROVA L.V. ,   Microbiological Laboratory, Republican TB Dispensary, Yoshkar-Ola, Russian Federation
Published: September 2021

The review presents data on proven clinical manifestations of the disease caused by non-tuberculosis mycobacteria. It was determined that pulmonary mycobacteriosis is one of the most common clinical forms of this mycobacterial infection, which is characterized by intoxication and respiratory syndromes. Dust in the air of the working area, as a professional factor, contributes to the emergence of pneumoconiosis and silicosis associated with mycobacteria. It is proved that M. avium has the ability to damage the intestinal mucosa, causing bacteremia and secondary damage to the bone marrow and spleen. The researchers point to the fact that non-tuberculosis mycobacteria can cause lymphadenopathy with lesions of the intraabdominal and cervical lymph nodes. Also, there is the possibility of mycobacteriosis of the skin. It is proved that mycobacterial infection contributes to the development of calcification of mitral, aortic valves and coronary arteries. It was determined that in the etiology of acute pancreatitis mycobacteriosis also plays definite role. Keywords: Mycobacteriosis, non-tuberculosis mycobacteria, clinical presentations, epidemiology.
THE IMPACT OF COLOUR ON STUDENTS’ PERCEPTION IN LEARNING SPACES
Authors: Baper Salahaddin Yasin , Husein Husein Ali , Salim Sazgar Samir
Published: September 2021

Color has a crucial impact on students’ perception. It encourages the learning atmosphere to be affiliated with the anticipated learning outcomes. The purpose of this study is to investigate the impacts of contextual colors on student’s perception of interior spaces and to validate previous related studies that emphasize on colors as a media to convey meanings that affect behaviors and students’ perception as well. Accordingly, the objective of this study is to determine and validate previous related studies regarding the impact of background color on student’s perception. Meanwhile the study evaluates the previous relevant models in order to validate or reject previous assumptions. The study concentrates on quantitative survey method using in depth questionnaire to determine student’s perception at UHD-University of Human Development, Sulaimani. Seven Colors from Munsell color system (yellow, green, blue, purple, white, and black, grey) are applied in the test in order to indicate the students’ perceptual status. The results show that cool colors like white, green and blue are mostly recommended for educational spaces. These colors affected positively the perception of respondents and add feeling of hope, curiosity and satisfaction to the group. In contrast dark colors (black and grey) are indicated as colors of worry and fear. The findings demonstrate that environments colors play an important effect on student’s perception. The study concluded that colors affect the behavior, performance and mood of the space users.
O corpo humano no cotidiano: analogias como recurso no ensino morfofuncional
Authors: Queiroz Tassio Danilo Rego de , Siebra Sabrina Mércia dos Santos , Júnior José Edvan de Souza , Nascimento Ellany Gurgel Cosme do , Maia Allyssandra Maria Lima Rodrigues , Fernandes Cleanto Rogério Rego
Published: September 2021

Objetivo: Relatar a experiência na utilização de analogias por monitores como metodologia ativa de ensino e aprendizagem dos componentes curriculares morfofisiológicos do curso de medicina. Relato de experiência: Cinco analogias foram desenvolvidas comparando objetos do dia a dia com as seguintes estruturas do corpo humano: miocárdio, capilares sinusoidais, células ciliares do epitélio respiratório, melanócitos epidérmicos e células ganglionares da retina. A atividade consistiu em comparar as semelhanças estruturais e funcionais de diferentes regiões do corpo humano com sua contraparte cotidiana, bem como evidenciar as suas diferenças, com o auxílio de imagens sem descrição mostradas aos alunos. O trabalho foi realizado nas aulas de laboratório por monitores de Histologia com sessenta alunos do primeiro e segundo semestres do curso de Medicina. Considerações finais: As analogias foram desenvolvidas e aplicadas com sucesso, as discussões foram além do objetivo inicial em algumas situações, sendo discutida, em todos os casos, a limitação da analogia, evitando o desenvolvimento de equívocos. As analogias são ferramentas úteis para o ensino e aprendizagem das ciências morfológicas, o que requer mais estudos para testar seu uso e eficácia.
Análise da influência dos hormônios sexuais na Doença de Alzheimer: revisão integrativa de literatura
Authors: Fonseca Bárbara Souza , Araujo John Klysman , Borges João Pedro Moraes , Mota Letícia Damasceno Janhaki , Miranda Luíza Vitória Evangelista de , Fernandes Tenylle Botelho , Santos Tereza Paula Pereira , Barbosa Sabrina Suellem Soares , Santos Mariane Costa , Souza Clarissa Leal Silva e
Published: September 2021

Objetivo: Analisar a influência dos hormônios sexuais na fisiopatologia e predisposição da Doença de Alzheimer, além dos seus benefícios neuroprotetores. Métodos: Trata-se de uma revisão integrativa da literatura e foi realizada nas bases de dados PubMed, Biblioteca Virtual em Saúde (BVS) e Scientific Electronic Libray Online (SciELO), utilizando palavras chaves incluídas nos Descritores em Ciências da Saúde (DeCS), em suas variantes na língua inglesa e portuguesa, nas seguintes combinações utilizando o operador booleano AND: “Doença de Alzheimer AND Hormônios Sexuais” e “Alzheimer Disease AND Sex Hormones”. Resultados: Foram selecionados 18 artigos para revisão. A partir da leitura dos artigos foi observado as diferenças sexuais na Doença de Alzheimer, mediadas principalmente pelos hormônios esteroidais. Verificou-se a atividade neuroprotetora desses hormônios contra processos inflamatórios no Sistema Nervoso Centra Considerações finais: Os estudos mostram a participação dos hormônios sexuais na fisiopatologia da doença de Alzheimer. As alterações desses esteroides influenciam em diferentes sítios, como: proteínas, organelas, células neuronais e da glia, resultando no processo neurodegenerativo que caracteriza a doença. Portanto, considera-se um campo promissor em pesquisas voltadas para a terapia dessa demência, inclusive destacando quais seriam mais benéficas para cada sexo.
Assessing the Unacquainted: Inferred Reviewer Personality and Review Helpfulness
Authors:   University of North Carolina at Charlotte, Liu Angela Xia , Li Yilin ,   Tsinghua University, Xu Sean ,   Tsinghua University
Published: September 2021

This work examines the question of who is more likely to provide future helpful reviews in the context of online product reviews by synergistically using personality theories and data analytics. It trains a deep learning model to infer a reviewer’s personality traits. This enables analyses to reveal the role of personality traits in review helpfulness among a large population of reviewers. We develop hypotheses on how personality traits are associated with review helpfulness, followed by hypotheses testing that confirms that higher review helpfulness is related to higher openness, conscientiousness, extraversion, and agreeableness and to lower emotional stability. These results suggest the appropriateness of using these five personality traits as inputs for developing a model for predicting future review helpfulness. Based on an ensemble model using supervised classification algorithms, we develop a predictive model and demonstrate its superior performance. Theoretical and practical implications are discussed.
Leveraging Machine Learning for Enantioselective Catalysis: From Dream to Reality
Authors: Rinehart N. Ian , Zahrt Andrew F. , Denmark Scott
Published: September 2021

Catalyst optimization for enantioselective transformations has traditionally relied on empirical evaluation of catalyst properties. Although this approach has been successful in the past is it intrinsically limtied and inefficient.  To address this problem, our laboratory has developed a fully informatics guided workflow to leverage the power of artificial intelligence (AI) and machine learning (ML) to accelerate the discovery and optimization any class of catalyst for any transformation. This approach is mechanistically agnostic, but also serves as a discovery platform to identify high performing catalysts that can be subsequently investigated by with physical organic methods to identify the origins of selectivity.
Contribution to the Discovery of a Novel Medicine for a Neuromuscular Disease and of other Promising Molecules for the Treatment of Neurodevelopmental and Neurodegenerative Diseases
Authors: Ratni Hasane
Published: September 2021

Nervous system disorders affect millions of people around the world, through a very broad range of diseases. Here we describe our contribution to find a treatment for patients suffering from three of those diseases. The first one, autism spectrum disorder (ASD), affects approximately one in every 59 children in US. The second one, spinal muscular atrophy (SMA) is a rare disease affecting one in 1 in 10000 live births worldwide, often leading to death if untreated. The third one, Alzheimer’s disease (AD) is a very well known devastating disease with an estimated 50 million people living with AD and other dementia, a number expected to triple by 2050. Our strategy to address those diseases was directed towards the discovery of a selective vasopressin 1a (V1a) antagonist for ASD, a splicing modifier of the survival of motor neuron 2 (SMN2) for SMA, and finally a g-secretase modulator (GSM) for AD. In the frame of our GSM project, we also reported the discovery of a bridge piperidine moiety as a bioisostere for a phenyl moiety with an improved drug-like profile.
«Futuras glorias annuncia, tàm beneficas, quàm claras»: profecía y esperanza criolla en el poema Hispano-Latino (1687) de Rodrigo de Valdés
Authors:   Vanderbilt University, López Andrea V.
Published: September 2021

Rodrigo de Valdés (1609-1682), sacerdote de la Compañía de Jesús nacido en Lima y descendiente de los primeros conquistadores del Perú, dedicó más de diez años a la elaboración del Poema Heroyco Hispano-Latino Panegyrico de la Fundación, y grandezas de la muy noble, y Leal Ciudad de Lima (1687). El resultado de sus esfuerzos fue un extenso poema en que la erudición propia de la estética barroca acompaña una de las más tempranas manifestaciones de la conciencia criolla que se diferencia de los españoles peninsulares en el virreinato del Perú. El poema Hispano-Latino de Valdés cuenta con 572 estrofas y 412 notas que glosan el contenido de los versos. La tradición clásica pagana y bíblica, así como el conocimiento filosófico, histórico y geográfico que contiene el poema, configuran desde distintos ángulos una defensa de los derechos de los criollos en un tiempo en que el sistema encomendero los enfrentaba con los peninsulares.
Los defensores de la humanidad
Authors:   Universidad de Santiago de Compostela (España), Pereira Menaut Antonio-Carlos
Published: September 2021

Un extraterrestre que llevara los últimos decenios observándonos desde otra galaxia podría tener la sensación de estar presenciando una carrera en la que la técnica ejerce más y más atributos de carácter divino (o considerados hasta ahora como propios de Dios), como seleccionar el sexo o el color de ojos de los hijos, dotar a las personas de más memoria, hacerlas guapas o feas (lo segundo es menos probable), decidir qué vida es digna de ser vivida, y otros más, sin excluir la pretensión de ser inmortales. Pero el problema –resumidamente– es que, acabe esa carrera donde acabe, al final no va a ser fácil, por no decir imposible, privar a Dios de ninguno de sus atributos, mientras que es fácil que, de rebote, al intentar todo eso, se dañe al hombre –sobre todo al hombre común–, y quizá lo estemos haciendo ya. Uno se pregunta, entonces, quién defiende realmente lo humano.
MILITARY SPHERE OF NATIONAL SECURITY OF THE REPUBLIC OF BELARUS: OBJECTIVE NECESSITY AND VECTOR OF DEVELOPMENT
Authors: Ксенофонтов Владислав Анатольевич
Published: September 2021

Рассмотрены основные теоретико-методологические аспекты функционирования военной сферы национальной безопасности Республики Беларусь. Подчеркивается ее объективная необходимость как важнейшего фактора обеспечения стабильности белорусского общества и государства, перспектив их развития. Показаны основные приоритеты развития военной сферы национальной безопасности.

The article considers main theoretical and methodological aspects of the functioning of the military sphere of the national security of the Republic of Belarus. The article emphasizes its objective necessity as the most important factor in ensuring the stability of the Belarusian society and state, as well as the prospects for their development. Main priorities of the development of the military sphere of national security are shown.
IMAGES OF THE FUTURE OF RUSSIA AND YOUTH POLICY: A SOCIO-PHILOSOPHICAL ANALYSIS
Authors: Козлова Наталия Николаевна , Овчарова Ольга Геннадиевна , Рассадин Сергей Валентинович
Published: September 2021

Авторы проводят анализ дискурса «образ будущего» в современной социально-политической мысли. Разделяя позицию З. Баумана о риторической манифестации власти о приватизации будущего, авторы обращают внимание на имманентно присущую природе политики функцию целеполагания, в том числе выработке и реализации коллективных целей, ориентированных на будущее. Анализируя молодежную политику в современной России, авторы приходят к выводу, что российское государство стремится адаптировать запросы молодых людей под собственные образы будущего великой и сильной державы, расставляя акценты на воспитание гражданственности и патриотизма. Авторы полагают, что для повышения эффективности государственного управления при разработке национальных проектов необходимо учитывать взгляд молодежи на будущее страны.

The authors analyze the discourse «the image of the future» in modern sociopolitical thought. Sharing the position of Z. Bauman on the rhetorical manifestation of the authorities about the privatization of the future, the authors pay attention to the goalsetting function inherent in the nature of politics, including the development and implementation of collective goals oriented towards the future. Analyzing the youth policy in modern Russia, the authors come to the conclusion that the Russian state seeks to adapt the needs of young people to its own images of the future of a great and strong power, placing emphasis on the education of citizenship and patriotism. The authors believe that in order to improve the efficiency of public administration, when developing national projects, it is necessary to take into account the view of young people on the future of the country.
Analysis of Dual Null Field Methods for Dirichlet Problems of Laplace’s Equation in Elliptic Domains with Elliptic Holes: Bypassing Degenerate Scales
Authors:   National Sun Yat-sen University, Li Z.C. , Huang H.T. ,   I-Shou University, Zhang L.P. ,   Zhejiang University of Technology, Lempert A.A. ,   Matrosov Institute for System Dynamics and Control Theory of Siberian Branch of Russian Academy of Sciences, Lee M.G. ,   Chung Hua University
Published: September 2021

Dual techniques have been used in many engineering papers to deal with singularity and ill-conditioning of the boundary element method (BEM). Our efforts are paid to explore theoretical analysis, including error and stability analysis, to fill up the gap between theory and computation. Our group provides the analysis for Laplace’s equation in circular domains with circular holes and in this paper for elliptic domains with elliptic holes. The explicit algebraic equations of the first kind and second kinds of the null field method (NFM) and the interior field method (IFM) have been studied extensively. Traditionally, the first and the second kinds of the NFM are used for the Dirichlet and Neumann problems, respectively. To bypass the degenerate scales of Dirichlet problems, the second and the first kinds of the NFM are used for the exterior and the interior boundaries, simultaneously, called the dual null field method (DNFM) in this paper. Optimal convergence rates and good stability for the DNFM can be achieved from our analysis. This paper is the first part of the study and mostly concerns theoretical aspects; the second part is expected to be devoted to numerical experiments.
How does my training as an applied behavioural analysis practitioner influence my development as a Music Therapy student?
Authors:   , Manere Anthony
Published: September 2021

The current study is attempting to answer the research question “the impact my previous ABA training may have on my current practice as a must therapy student?”. The goal of this study is to gain insight on my own clinical practice in order to develop a more well-rounded therapeutic approach. I used a secondary analysis of session notes from my student music therapy placement at an intermediate school. A deductive content analysis was used to explore data within separate categories underpinning either humanistic or behavioural approaches. The data collected into these categories was qualitatively considered to create themes and to support how behavioural methods manifest in my current practice. The study assumes that a behavioural way of thinking is already present in my practice and seeks to investigate how has also manifested in my professional identity. The study acknowledges that although the field of music therapy can take on a variety of different therapeutic approaches, the training that I have received at Victoria University of Wellington has a largely humanist emphasis.

Overall, the study found that the use of either behavioural or humanistic approaches are situationally dependent on the client, activity, or therapeutic goal. In both goal setting, and musical choice, there was a spectrum of attitudes falling between the theories while other methods such as therapeutic relationship or prompting held a unique perspective falling into one or the other. I feel that the use of dual methodologies in my practice compliment the limitations and advantages that each approach may present. As these approaches both fall on opposite ends of the “theoretical spectrum”, they pair to create a middleground between a holistic, client-centered practice, and a tightly structured, goal-oriented practice.

KEYWORDS:Music therapy, behaviourism, humanism, principles, content analysis, secondary analysis, deductive, qualitative
Murabaha İşlemlerinin Faizsiz Finans Muhasebe Standartlarına Göre Muhasebeleştirilmesinin TMS/TFRS’ler Açısından Karşılaştırmalı İncelemesi
Authors: KILINÇ Yavuz
Published: September 2021

Murabaha sözleşmesi, peşin satın alma imkânı olmayan bir kişi/işletmenin İslami Finansal Kuruluşlar (İFK) aracılığı ile malı, vadeli olarak satın alma imkanı ortaya çıkaran sözleşme türüdür. Bu açıdan murabaha sözleşmesi bir satış sözleşmesi olarak karşımıza çıkar. Murabaha sözleşmelerinin geleneksel bankacılık sistemi içerisinde bir karşılığı bulunmamaktadır. Bunun yerine banka kişi/işletmenin ihtiyaç duyduğu ürünü satın alabilmesine yönelik kredi sağlayabilmektedir. Banka bu kredinin karşılığı olarak da belirli bir oranda faiz geliri elde edecektir. İslam dini faizi kesin olarak yasakladığından tüketiciler, bankalardan bu yolla kredi elde etme yerine murabaha sözleşmeleri kapsamında satın almak istedikleri ürünü vadeli olarak satın alabilmektedirler. Çünkü İslami finansal kuruluşlarla yapılan murabaha sözleşmesi şeriat hükümlerine uygundur ve bu nedenle Müslümanlar tarafından daha da kullanılabilir hale gelmektedir. Bu makalenin amacı, İslami Finansal Kuruluşlar tarafından gerçekleştirilen murabaha işlemlerinin muhasebeleştirilmesine yönelik gerek TMS/TFRS’ler gerekse FFMS’lerin içeriğinin karşılaştırmalı olarak incelenmesidir.
Gender estimation from angular parameters of mandible in Turkish adults
Authors: SERTEL MEYVACI Seda , GÖLLER BULUT Duygu , ÖZTÜRK Ayşe Tuğçe , ANKARALI Handan
Published: September 2021

Aim: In this study, it was aimed to evaluate the effect of angular parameters, which are a part of mandibular morphometry, on gender assessment with the help of cone beam computed tomography (CBCT).

Material and Methods: A total of 197 healthy adults, 100 females and 97 males, aged between 18-68 years were included in our study. Ten angular parameters of the mandible were evaluated using CBCT. Independent samples t-test was used to compare the gender for each of the age and angle measurements. In addition, the success of the angles in gender diagnosis was examined by a stepwise linear canonical differential analysis. Statistical significance level was accepted as p0.05). In order to eliminate the effect of age difference, a total of 11 variables including age were comprised in the model, and discriminant analysis was performed with the stepwise variable elimination method to select only the variables that could make significant gender discrimination. As a result of variable elimination, we found that the overall correct classification success of the discriminant function, which includes a total of 4 angles, sexually dimorphic right α angle, left Go angle, right β angle, and left α angle, was 71.5%.

Conclusion: This study showed that among the angular parameters of the mandible, the left Go angle being the highest, the right α angle, right β angle and left α angles have sexual dimorphic properties, and gender estimation can be made with 71.5% overall accuracy with the discriminant function containing these parameters.
Confianza y satisfacción de estudiantes universitarios durante la pandemia de COVID-19
Authors: Cantú Martínez Pedro César
Published: September 2021

El propósito de esta indagación fue conocer los niveles de confianza y satisfacción de estudiantes universitarios hacia las actividades emprendidas por instancias gubernamentales, civiles y educativas. Estudio descriptivo y correlacional, participaron 54 alumnos de la Universidad Autónoma de Nuevo León –México-. Los resultados demuestran que los participantes brindan muy buena confianza y buena satisfacción a la Secretaría de Salud Estatal, la atención en salud ofrecida por instituciones privadas y autoridades de la dependencia universitaria. Con moderada confianza y satisfacción fueron catalogadas las agrupaciones ciudadanas y organismos empresariales. Subsiste una relación estadísticamente significativa entre la confianza y satisfacción expresada.
Pseudo-Chilblains in a COVID-19 Patient
Authors: Moutinho-Guilherme Ricardo , Bessa Gisela
Published: September 2021

The aim of this case is to describe an example of cutaneous manifestations caused by COVID-19 infection, helping to better understand the disease and support an early clinical suspicion. This case addresses a 36-year-old patient with COVID-19 infection, symptomatic, with mild complaints. Seven days after the start of the clinic, she exhibited dermatological lesions in the acral areas bilaterally on her hands. The presence of erythematous-violet papules/vesicles was found in the dorsal extensor zones of the fingers, with local inflammatory signs, skin rash, flushing, edema, local burning sensation, itching and pain. Pseudo-chilblains were assumed as diagnostic hypotheses. She underwent symptomatic treatment, having achieved complete resolution at 10 days, with no subsequent sequelae.Attention should be paid to the fact that COVID-19 may present only with cutaneous manifestations, therefore these may serve as an indicator of the disease in suspected cases.
Diagnóstico Precoce do Cancro Oral: Prevenção Secundária sob a Forma de Rastreio Oportunista ou Rastreio Organizado?
Authors: Pinto Silva Joana Filipa
Published: September 2021

Oral cancer is the sixth most common cancer in the world with around 300 000 new cases annually, with a five-year survival rate after diagnosis of 40%.2 In Portugal, there are about 1000 new cases per year and 500 deaths.2 Oral cancer appears more frequently in men (2: 1 ratio male / female) after the fourth decade, although it has been documented worldwide, an increased number of this cancer in younger adults and women. [...]
Lições da Primeira Evangelização
Authors: Boff Clodovis M.
Published: September 2021

Que nos ensina a primeira evangelização do nosso continente a nós que estamos envolvidos com a “nova evangelização”? Não se trata aqui de fazer o processo do passado, mas de aprender com ele em função de nosso presente. O passado pode nos sugerir o que devemos fazer e também o que não devemos. “A história é mestra de vida” – repetiam os antigos. Que podemos, pois, aprender com os primeiros missionários da América Latina?

Desenvolveremos a seguir algumas lições importantes que podemos tirar de nosso passado.
A Qualitative Study Examining Macao’s Parents’ Attitude towards Native and Non-native English-speaking Teachers for Private Online Synchronous One-on-one English Lessons
Authors: Chan Cheng Tak
Published: September 2021

In terms of English learning, whether native English-speaking teachers (NESTs) surpass non-native English-speaking teachers (NNESTs) or vice versa has been a heated topic. These two types of teachers have their own respective benefits and drawbacks with respect to English teaching. Most of the current related studies are on the traditional educational classroom setting in both secondary school and higher education. However, the study of the virtual learning platform as a method of teaching English is rare. This research displays valuable significance in identifying whether parents in Macao have a preference towards NESTs and NNESTs before they purchase the online synchronous one-on-one English lessons for their children. This qualitative study, after two participants were interviewed, concludes that they both prefer NESTs due to their authentic accent and pronunciation and believe it is more suitable in such a speaking-andlistening oriented online lesson. Price is not the prioritized factor to consider. They are generally satisfied with the teaching style of the online NESTs but it is also important to take note of the teaching approach conducted in the online lessons towards children, to ensure that it holds their interest appropriately.
TECHNOLOGIES FOR TRAINING SPECIALISTS IN THE HOTEL AND CATERING INDUSTRY IN UKRAINE IN THE CONTEXT OF LIFELONG LEARNING
Authors:   Mykolaiv National Agrarian University, Faculty of Management, Department of Hotel and Restaurant Business and Business Organization, Mykolaiv, Ukraine, ANDRIUSHCHENKO Iana E. , IVANENKO Tetiana Ya. ,   Mykolaiv National Agrarian University, Faculty of Management, Department of Hotel and Restaurant Business and Business Organization, Mykolaiv, Ukraine, BURAK Valentina H. ,   Kherson State University, Faculty of Business and Law, Department of Hotel and Restaurant and Tourist Business, Kherson, Ukraine, KOVALENKO Ganna V. ,   Mykolaiv National Agrarian University, Faculty of Management, Department of Enterprise Economics, Mykolaiv, Ukraine, ZAMFERESKO Olena V. ,   Lviv Higher Profession School of the Trade and Service Sphere, Lviv, Ukraine
Published: September 2021

This article is relevant, as staff training in the context of lifelong learning increases the value of travel services for customers, providing added value in the hotel and catering industry. The purpose of the paper is to study the technologies of training specialists in the hotel and catering industry in the context of lifelong learning for the formation of the life cycle of an employee in the hospitality industry. The research methodology is based on statistical analysis of indicators for distribution. The results demonstrate that there are differences in the technologies for training specialists in the hospitality industry in terms of such characteristics, as: the provider of educational services, the initial educational level, the position held by the specialist and the status in the society. The practical value of the research lies in the possibility of using the existing methodology of the life cycle of training a specialist in the practice of hotel and catering industry.
The optimization of binary group sequences generated by the nonlinear code multiplexing
Authors:   Federal State Budgetary Institution ", Berdyshev O. Y. ,   16 Central Research and Testing Institute of the Order of the Red Star named after Marshal of the Communication Troops A. I. Belov",   of the Ministry of Defense of the Russian Federation
Published: September 2021

This paper presents the challenge of optimization of binary group sequences obtained from the nonlinear code multiplexing. It shows that at optimal element wise methodology for group sequences in a full system of orthogonal Walsh functions, a maximum criterion for the minimum distance of group sequences is equal to a maximum criterion for the minimum correlation response for the information orthogonal Walsh functions which contain group sequences. After a nonlinear code multiplexing group sequences are often contained errors, that makes using this method of multiplexing more difficult. To eliminate this source of errors the algorithm of optimization of group sequences was suggested. In this algorithm some elements of group sequences can be replaced with the opposite elements. Additionally, the algorithm of receiving of the entire group sequence among the nearest group sequences was developed. This algorithm provides considerable increasing of immunity while group sequence receiving unlike the other algorithm of element-to-element receiving in a full system of orthogonal Walsh functions.
Innovative Potential of the Smart City
Authors:   Institute of Economics of the Ural branch of Russian Academy of Sciences, Semyachkov K.A.
Published: September 2021

This study aims to systematize the main factors of the smart city model that affect the increment of the territorial innovative potential. The development of digital technologies and new forms of socio-economic interactions built on their basis has a significant impact on urban transformations and the innovative processes associated with the development of the urban environment. Methodologically, the study relies on a system logical analysis of Russian and international publications in this field. The study reveals the features of the smart city model that significantly increase the innovative potential of modern cities. It is shown that the smart city model enhances the effect of the factors that can significantly increase the innovative potential of a territory. The main factors of innovative development include the availability of digital infrastructure, the development of high-tech businesses and creative industries, social integration, and so on. The study has both theoretical and practical significance and its findings can be used in further research on the topic of smart cities and innovative development.