bluuebunny/crossref_metadata_2025 huggingface dataset:
ATFL1 (Anti-TFL1), a novel orthologue induces flowering in the masting alpine snow tussock, Chionochloa pallens (Poaceae)
Authors: * Samarth , Lee Robyn , Kelly Dave , Turnbull Matthew , Macknight Richard , Poole Anthony , Jameson Paula
Published: June 2021

Masting, the synchronous highly variable flowering across years by a
population of perennial plants, has been shown to be precipitated by
many factors including nitrogen levels, drought conditions, spring and
summer temperatures. However, the molecular mechanism leading to the
initiation of flowering in masting plants in particular years remains
largely unknown, despite the potential impact of climate change on
masting phenology. We studied genes controlling flowering in Chionochloa
pallens, a strongly masting perennial grass. We used a range of in situ
and manipulated plants to obtain leaf samples from tillers (shoots)
which subsequently remained vegetative or flowered. Here, we show that a
novel orthologue of TERMINAL FLOWER 1 (TFL1; normally a repressor of
flowering in other species) promotes the induction of flowering in C.
pallens (hence Anti-TFL1), a conclusion supported by structural,
functional and expression analyses. Global transcriptomic analysis
indicated differential expression of CpTPS1, CpGA20ox1, CpREF6 and
CpHDA6, emphasising the role of endogenous cues and epigenetic
regulation in terms of responsiveness of plants to initiate flowering.
Our molecular-based study has provided insights into the cellular
mechanism of flowering in masting plants and will supplement ecological
and statistical models to predict how masting will respond to global
climate change.
An Evaluation and Dissemination Model for the Machine Learning Embedded System Lifecycle in Clinical Practice Settings
Authors: besculides melanie , Gorbenko Ksenia , Smith Cardinale , Freeman Robert , Reich David , Kia Arash , Mazumdar Madhu
Published: June 2021

Machine learning (ML) algorithms are gaining popularity in clinical
practice settings due to their ability to process information in ways
that augment human reasoning. While tools that rely on output from ML
algorithms in the healthcare setting are appealing for their ability to
aid in clinical decision making and streamline workflows, their
implementation and effectiveness are not well documented. There is an
abundance of published ML literature that focuses on whether algorithms
can predict an outcome or predict it better than previous algorithms,
but a dearth of effort evaluating their implementation or impact on
patient outcomes. While developing and validating algorithms is an
important first step in research, comprehensive evaluation is needed
before application of ML algorithms in new settings is considered.
Evaluation should examine both the process of implementation and the
outcomes using a mix of qualitative and quantitative methods. This
commentary describes a model we developed to guide our institutional ML
evaluation efforts.
Urgent percutaneous transluminal septal myocardial ablation for left ventricular outflow tract obstruction exacerbated after surgical aortic valve replacement
Authors: Sasahira Yoshitaka , Yamada Ryotaro , Doi Naofumi , Uemura Shiro
Published: June 2021

Percutaneous transluminal septal myocardial ablation (PTSMA) is an
established procedure for treating symptomatic hypertrophic obstructive
cardiomyopathy. We report a case of urgent PTSMA for treating refractory
heart failure due to exacerbated obstruction of the left ventricular
outflow tract after surgical aortic valvular replacement to treat severe
aortic stenosis.
The factors that affecting shockwave lithotripsy treatment outcome of kidney stones
Authors: KAYRA MEHMET VEHBİ , GOREN Mehmet Resit , Ozer Cevahir , Kilinc Ferhat
Published: June 2021

Bacground: We aimed to analyze combination of the schockwave lithotripy
(SWL) success predictors. Methods: In this retrospective study, the
outcomes of the patients with kidney stones treated with SWL were
analyzed. Adult patients (≥18 years) with complete records with
non-contrast computed tomography (NCCT), stone analysis, laboratory data
were involved in the study. Patients who were with urinary system
anomalies, who were receiving alpha-blocker and/or calcium channel
blockers and whom with impaired kidney function were excluded. The
effect of stone density, skin-to-stone distance (SSD), perirenal tissue
density (PTD), subcutaneous tissue density (STD), stone size, stone
burden, stone localization, infundibulopelvic angle (IA), as well as
body mass index (BMI) and stone analysis results on the success of the
treatment was evaluated. Results: SSD, PTD, STD, stone localization, IA,
as well as body-mass index, did not have any association with SWL
success. Stone size and stone burden had a significant association with
treatment success (p = 0.0001), and the cut-off values determined for
stone size and stone burden were 12.95 mm (p = 0.0006) and 121.38 mm2 (p
= 0.004) respectively. Stone density also had a significant association
with treatment success (p = 0.0001), and the cut-off value determined
for stone density was 739 HU (Hounsfield Unit) (p = 0.001). Treatment
success was significantly lower in cystine and calcium oxalate
monohydrate stones compared to other stone types (p = 0.019).
Conclusion: Significant markers that determine SWL effectiveness are
stone size, stone burden, stone density and, besides, stone type.
Abatacept-based Graft-Versus-Host-Disease Prophylaxis in Haplo-identical Hematopoietic Cell Transplant: Single Center Experience in a High-Risk Cohort
Authors: Raffa Enass , Srinivasan Anand , Wall Donna , Schechter Tal , Ali Muhammad , Krueger Joerg , chiang Kuang-Yueh
Published: June 2021

Post-transplant cyclophosphamide (PTCy) has become the most popular
approach in haplo-identical hematopoietic cell transplant (haplo-HCT).
Although there are reports of a small number of adult patients in the
literature who experienced graft failure and were re-transplanted with a
haploidentical donor with PTCy prophylaxis, there is still insufficient
guidance for patients with specific contraindications/complications to
cyclophosphamide and virtually no data in the pediatric setting.
Abatacept (Aba), a T cell co-stimulation blockade, has been shown in
previous studies to prevent severe acute graft-versus-host disease
(GVHD) with minimal toxicity and durable engraftment. We report the
efficacy of Aba-based GVHD prophylaxis in four pediatrics patients (ages
2-12 years) who received a haplo-HCT with peripheral blood stem cells
(PBSC). Three patients had previous transplants. One patient developed
acute GVHD of skin stage 3 and one patient had both stage 3 skin and
stage 1 GI acute GVHD. Two patients had mild chronic skin GVHD. All 4
patients are alive with full donor chimerism and without disease at 7-23
months follow up, weaning or off immunosuppressive agents with no
complications. Successful haplo-HCT utilizing an Aba- based regimen can
result in reliable engraftment and acceptable GVHD. However, our small
sample size limits generalizability and encourages the consideration of
a larger prospective trial to validate these results in the haplo-HCT
setting.
Can propylthiouracil induce autoimmune-related immunotoxicity?
Authors: Bajkin Ivana , Golubovic Sonja , Icin Tijana , Stepanovic Kristina , Ilic Tatjana
Published: June 2021

Introduction. The use of propylthiouracil can be associated with mild adverse reactions, but severe complications such as agranulocytosis and vasculitis can also be seen. Direct toxicity and immune-mediated induction of anti-neutrophile cytoplasmic antibodies have been described as possible mechanisms responsible for agranulocytosis. The majority of vasculitis is antimyeloperoxidase antibodies associated, but the exact mechanism for anti-neutrophile cytoplasmic antibodies-associated vasculitis as an adverse effect of propylthiouracil treatment is still unclear. Case report. We presented a 61-year-old female patient with Graves? disease who experienced a fever and throat pain two weeks after propylthiouracil therapy was initiated. Agranulocytosis alongside basal left-sided pneumonia was noted. Propylthiouracil was discontinued, and the treatment with broad-spectrum antibiotics was started, as well as Lugol?s solution, methylprednisolone, and granulocyte-colony stimulating factor. Further course of treatment was complicated by the occurrence of a generalized erythematous-papillomatous rash. The patient was diagnosed with agranulocytosis and antimyeloperoxidase, anti-neutrophile cytoplasmic antibodies positive vasculitis as an adverse effect of propylthiouracil. Conclusion. Patients presenting with concomitant agranulocytosis and anti-neutrophile cytoplasmic antibodies-associated vasculitis as a complication of propylthiouracil therapy for Graves? disease are rare in clinical practice. Prompt discontinuation of the antithyroid drug is of great importance to reduce damage to target organs. Similarities in the pathogenesis of both conditions could be the potential explanation for these two adverse events occurring at the same time, which points out the need for a deeper understanding of this topic.
Association Between Glucagon-Like Peptide 1 Receptor Agonist and Sodium–Glucose Cotransporter 2 Inhibitor Use and COVID-19 Outcomes
Authors: Kahkoska Anna R. , Abrahamsen Trine Julie , Alexander G. Caleb , Bennett Tellen D. , Chute Christopher G. , Haendel Melissa A. , Klein Klara R. , Mehta Hemalkumar , Miller Joshua D. , Moffitt Richard A. , Stürmer Til , Kvist Kajsa , Buse John B.
Published: June 2021

Objective: To determine the respective associations of premorbid glucagon-like
peptide-1 receptor agonists (GLP1-RA) and sodium-glucose-linked cotransporter 2
inhibitors (SGLT2i) use, compared to premorbid dipeptidyl peptidase-4 inhibitor
(DPP4i) use, with severity of outcomes in the setting of COVID-19 infection.

Research Design
and Methods: We analyzed observational data from SARS-CoV-2-positive adults in the National COVID Cohort Collaborative, a multicenter, longitudinal U.S. cohort (January 2018–February
2021) with a prescription for GLP1-RA, SGLT2i, or DPP4i within 24 months of positive
SARS-CoV-2 PCR test. The primary outcome was 60-day mortality, measured
from positive SARS-CoV-2 test date. Secondary outcomes were total mortality
during the observation period, and emergency room visits, hospitalization, and
mechanical ventilation within 14 days.  Associations were quantified with odds
ratios (OR) estimated with targeted maximum likelihood estimation using a super
learner approach, accounting for baseline characteristics.

Results: The study
included 12,446 individuals (53.4% female, 62.5% White, mean±SD age 58.6±13.1
years). The 60-day mortality was 3.11% (387/12,446), with 2.06% (138/6,692) for
GLP1-RA use, 2.32% (85/3,665) for SGLT2i use, and 5.67% (199/3,511) for DPP4i
use. Both GLP1-RA and SGLT2i use was associated with lower 60-day mortality
compared to DPP4i use (OR (95% confidence intervals (95%CI)): 0.54 (0.37–0.80)
and 0.66 (0.50–0.86), respectively). Use of both medications was also associated
with decreased total mortality, emergency room visits, and hospitalizations.

Conclusions: Among SARS-CoV-2-positive adults, premorbid GLP1-RA
and SGLT2i use, compared to DPP4i use, was associated with lower odds of mortality
and other adverse outcomes, although DPP4i users were
older and generally sicker.
Oral Glucose Tolerance Test Results in Pregnancy Can Be Used to Individualize the Risk of Future Maternal Type 2 Diabetes Mellitus in Women With Gestational Diabetes Mellitus
Authors: Hiersch Liran , Shah Baiju R. , Berger Howard , Geary Michael , McDonald Sarah D. , Murray-Davis Beth , Halperin Ilana , Retnakaran Ravi , Barrett Jon , Melamed Nir
Published: June 2021

OBJECTIVE: We
aimed to quantify the risk of future maternal T2DM in women with GDM based on
the type and number of abnormal 75g-OGTT values and the diagnostic criteria
used for the diagnosis of GDM.

RESEARCH
DESIGN AND METHODS: We conducted a population-based
retrospective cohort study of all nulliparous women with a live singleton birth
who underwent testing for GDM using a 75g-OGTT in Ontario, Canada (2007-2017).
We estimated the incidence rates (per 1000 person years), overall risk
(expressed as adjusted hazard ratio [aHR]), and risk at 5-year post the index
pregnancy of future maternal T2DM. Estimates were stratified by the type and
number of abnormal OGTT values, as well as by the diagnostic criteria for GDM
(Diabetes Canada vs. IADPSG criteria).

RESULTS: A
total of 55,361 women met the study criteria. The median duration of follow-up
was 4.4 (IQR 2.8-6.3, maximum 10.3) years. Using women without GDM as reference
(incidence rate 2.18 per 1000py), women with GDM were at an increased risk of
future T2DM, with the risk being higher for the Diabetes Canada compared with
the IADPSG criteria (incidence rate 18.74 [95%-CI 17.58-19.90] vs. 14.07 [95%-CI
13.24-14.91] per 1000py, respectively). The risk of future maternal T2DM
increased with the number of abnormal OGTT values, and was highest for women
with 3 abnormal values (incidence rate 49.93 per 1000py; aHR 24.57 [95%-CI
21.26-28.39]). The risk of future T2DM was also affected by the type of OGTT
abnormality: women with an abnormal fasting value had the greatest risk while
women with an abnormal 2-hour value had the lowest risk for future T2DM (aHR
14.09 [95%-CI 12.46-15.93) vs. 9.22 [95%-CI 8.19-10.37]), respectively). Similar
findings to those described above were observed when the risk of T2DM at a
fixed time point of 5-years post the index pregnancy was considered as the
outcome of interest.

CONCLUSION: In women
with GDM, individualized information regarding the future risk of T2DM can be provided
based on the type and number of abnormal OGTT values, as well as the diagnostic
criteria used for the diagnosis of GDM.
Abordagens da Psicanálise na literatura brasileira hoje
Authors: Rios Cleusa
Published: June 2021

Entrevista com Cleusa Rios Passos, professora titular da Faculdade de Filosofia Letras e Ciências Humanas da Universidade de São Paulo, que tem experiência na área de Letras, com ênfase em Teoria Literária, atuando principalmente nos seguintes temas: Guimarães Rosa, estudo das formas narrativas e confluências entre crítica literária e psicanálise. Desde 2005, coordena (com outro docente) o grupo de pesquisa "Crítica Literária e Psicanálise". Entrevista: Elisabeth CardosoEdição: Ana Paula Rodrigues da Silva, Thiago Fonseca (TV-PUC)Música: PIPA estúdio
Quantum-chemical modeling of the processes of cadmium sulfide and cadmium selenide films synthesis in aqueous solutions
Authors:   Lviv Polytechnic National University, Sozanskyi M. A. , Shapoval P. Yo. ,   Lviv Polytechnic National University, Stadnik V. E. ,   Lviv Polytechnic National University, Guminilovych R. R. ,   Lviv Polytechnic National University, Kurylo O. P. ,   Lviv Polytechnic National University
Published: June 2021

The quantum-chemical modeling of the synthesis process chemistry of CdS and CdSe in aqueos solutions was carried out. For that reason, the CdS synthesis simulation was carried out through the formation of Cd(II) complex forms with the trisodium citrate and ammonium hydroxide. At the CdSe synthesis, the sodium selenosulfate with and without trisodium citrate was used. It was established that this process passes through several intermediate stages with the transitional reactive complexes formation. On the basis of obtained data, the energy stages diagrams are constructed and the comparison of CdS and CdSe synthesis processes with various complexing agents has been carried out. The CdS and CdSe films were obtained by chemical synthesis method from an aqueous solution of cadmium salt, complexing and chalcogenizing agents. X-ray phase analysis confirmed the formation of desired compounds, which was predicted by modeling.
Micro- and nanostructured titanium(IV) oxide in sono-, photo- and sonophotocatalytic degradation of xanthene dye rhodamine b (Review)
Authors:   Lviv Polytechnic National University, Sukhatskyi Yu. V. , Znak Z. O. ,   Lviv Polytechnic National University, Chupinskyi D. V. ,   Lviv Polytechnic National University
Published: June 2021

Adsorption methods for removing Rhodamine B from wastewater and oxidative degradation methods based on the use of advanced oxidation processes (sonolysis, photolysis, sono-, photo- and sonophotocatalysis) are considered. It was established that naturally occurring materials (such as clays, zeolites, coal ash, anaerobic sludge, agricultural solid wastes) and their modified or activated analogues are used as adsorbents for the removal of Rhodamine B. The possible mechanism of photo- and sonophotocatalytic degradation of Rhodamine B in the presence of micro- and nanostructured titanium (IV) oxide is presented. The effectiveness of its application for degradation of Rhodamine B is analyzed.
Influence of electrode material on the electrochemical behavior of the absorbing solution of the quinhydrone method of gases purification from hydrogen sulfide
Authors:   Lviv Polytechnic National University, Slyuzar А. V. , Mertsalo І. P. ,   Lviv Polytechnic National University, Kozub M. І. ,   Lviv Polytechnic National University, Myliutyna P. V. ,   Lviv Polytechnic National University, Yakymenko Ya. O. ,   Lviv Polytechnic National University
Published: June 2021

The electrochemical behavior of carbonate solutions of the quinhydrone at different concentrations 1, 5, 10, 20, and 30 g/dm3 at the exposure time 0…12 days on different electrode materials – Ni and Au were studied by the cyclic voltammetry (CV) method. The catalytic properties of gold different from nickel in the anodic oxidation reactions of the quinhydrone catalyst are noted.
The structure formation features of gypsum-lime composite binders for non-autoclaved aerated concrete
Authors:   Lviv Polytechnic National University, Chekanskyi B. B. , Lutsyuk I. V. ,   Lviv Polytechnic National University, Pastushok V. R. ,   Lviv Polytechnic National University
Published: June 2021

The crystalline phases of hydration products of the gypsum-lime binder were identified using XRD analysis. The physical and chemical regularities of the structure formation processes in the model system “gypsum – quicklime – metakaolin – amorphous silica – water – borax” were established. The influence of the quicklime type and gypsum binder brand on the morphology and the size of the calcium sulfate dihydrate crystals were investigated. The relationship between processesof the structure formation of composite gypsum-lime binders under normal hardeningconditions and the physical and mechanical characteristics of the stone was established.
C9 Fraction inverse emulsion oligomerization conditions and characteristics of petroleum resins correlation
Authors:   Lviv Polytechnic National University, Subtelnyi R. О. , Kichura D. B. ,   Lviv Polytechnic National University, Kostiuk R. R. ,   Lviv Polytechnic National University, Danyliv A. A. ,   Lviv Polytechnic National University, Dzinyak B. О. ,   Lviv Polytechnic National University
Published: June 2021

It has been studied the production of petroleum resins by low-temperature inverse emulsion oligomerization of C9 fraction of diesel fuel pyrolysis liquid by-products. It is established that the determining factors of the C9 fraction of the inverse emulsion oligomerization are the following: reaction time, emulsifier concentration and phase ratio. Yield and physicochemical characteristics of oligomers сorrelations were established. Multiple linear regression of oligomer yield depends on the main significant parameters of the fraction C9 inverse emulsion oligomerization is proposed.
Іnvestigation of complex formation of cobalt (ІІ) ions with polyacrylic acid
Authors:   Lviv Polytechnic National University, Oliynyk L. P. , Makota О. І. ,   Lviv Polytechnic National University, Komarenska Z. M. ,   Lviv Polytechnic National University, Bernatska N. L. ,   Lviv Polytechnic National University
Published: June 2021

The process of formation of cobalt (II) ion complexes with polyacrylic acid, their influence on the size of the tangle of polyacrylic acid macromolecules and the concentration of monomer units in it have been studied. It is shown that the reaction at a temperature of 20–300 ºC forms a complex in which the cobalt ion binds two carboxyl groups of polyacrylic acid. Binding of the third carboxyl group to the complex is prevented by a sufficiently flexible polyacrylic acid chain. Increasing the temperature significantly increases the flexibility of the polyacrylic acid chain. The formation of complexes at elevated temperature proceeds in the first order by cobalt (II) ion and hydroxyl ion and by zero order – by polyacrylic acid. The change in the concentration of monomer units in the tangle of polyacrylic acid macromolecules during the formation of a complex with a cobalt (II) ion proceeds in the first order.
Energy analysis of the production line for canned carrot production
Authors:   Lviv Polytechnic National University, Huzova І. O. , Atamanyuk V. М. ,   Lviv Polytechnic National University
Published: June 2021

An energy-saving scheme for the production of candied carrots has been developed. The developed scheme includes: washing of raw materials with 1 % NaHCO3 solution, reduction of water consumption for blanching, reduction of syrup consumption for saturation of raw materials with sugar. A new drying technology is introduced: candied fruits are dried in a variable temperature mode, namely: in the initial stages with a heat agent at a temperature of 70 °C, at the final stage – with a heat agent at a temperature of 20 °C. The process of modeling the traditional and energy-saving scheme of candied carrot production in the universal simulation software ChemCad is carried out. The simulation results are analyzed. It is proved that the total energy efficiency of the implemented technology is 340.4 MJ / h or 354.6 kJ / kg of finished product.
The properties of hydrogel membranes obtained by modification in the volyme
Authors:   Lviv Polytechnic National University, Baran N. M. , Suberlyak O. V. ,   Lviv Polytechnic National University, Grytsenko O. M. ,   Lviv Polytechnic National University, Moravskyi V. S. ,   Lviv Polytechnic National University
Published: June 2021

The method of the composite hydrogel membranes synthesis based on the 2-hydroxyethyl methacrylate (HEMA) and polyvinylpyrrolidone (PVP) with simultaneous modification in the volume by the mixture of polyamide-6 (PA-6) and PVP solution with varying the concentration of the reaction mixture in the water has been described in this study. The influence of the water content in the reaction composition on the physical mechanical properties and water absorption of the obtained membranes has been investigated.
НЕЙРОМЕРЕЖЕВА СИСТЕМА ПІДБОРУ ІНВЕНТАРЯ ДЛЯ НАСТІЛЬНОГО ТЕНІСУ
Authors: Тазетдінов Валерій Абударович , Сисоєнко Світлана Володимирівна
Published: June 2021

У статті досліджується питання оптимізації пошукових процесів та актуальність використання штучних нейронних мереж для підбору інвентаря для настільного теннісу. Проводиться аналіз останніх публікацій в обраній темі та розглядаються переваги штучнихнейронних мереж порівняно з традиційними видами знаходження рішень. Визначаються переваги використання комп’ютерних технологій з метою автоматизації процесів підбору інвентаря для настільного тенісу. За домопомгою нейронних мереж можна розв’язати будь-яку задачу. Проблема полягає лише у тому, щоб здійснити правильний вибір архітектури та структури нейронної мережі, алгоритму її функціонування та здійснити формалізацію вихідних даних, результату та відповідного перетворення. В роботі розглядаються варіанти різних побудов штучних нейронних мереж і алгоритми їх функціонування з метою вибору оптимального алгоритму. Аналіуються недоліки та переваги мереж з алгоритмом оберненого поширення похибки, RBF (штучних нейронних мереж із радіально-базисними активаційними функціями) та карти Кохонена. В статті також розглянуто задачу кластеризації ринку інвентаря для настільного тенісу. Результатом дослідження стало створення нейромережевої інформаційно-аналітичної системи «Neuro TT» для аналізу ринку інвентаря настільного тенісу з можливістю підбору оптимального поєднання накладок і основи. Розроблено структуру такої нейромережевої системи. Вона складається з трьох інформаційних банків, в яких міститься інформація про властивості основ і накладок, а такожвідомі комбінації таких поєднань накладок і основ. Елементи системи розташовуються на сервері і є незалежними один від одного. Використання такої системи дасть змогу передбачати тенденції розвитку ринку інвентаря для настільного тенісу, виробникам планувати та змінювати структуру виробництва, покупцям (гравцям) та продавцям повністю задовольнити інформаційні потреби. Використання такої системи дозволить передбачати тенденції розвитку ринку інвентаря для настільного тенісу, виробникам планувати та змінювати структуру виробництва, покупцям (гравцям) та продавцям повністю задовільніть інформаційні потреби.
ЛІНІЙНИЙ СУРОГАТНИЙ СИНТЕЗ РАМКОВИХ ТАНГЕНЦІАЛЬНИХ ВИХРОСТРУМОВИХ ПЕРЕТВОРЮВАЧІВ З ОБ’ЄМНОЮ СТРУКТУРОЮ СИСТЕМИ ЗБУДЖЕННЯ
Authors: Трембовецька Руслана Володимирівна , Гальченко Володимир Якович , Тичков Володимир Володимирович
Published: June 2021

Запропоновано математичний метод лінійного сурогатного параметричного синтезу рухомих рамкових тангенціальних накладних вихрострумових перетворювачів з однорідним розподілом густини вихрових струмів у зоні контролю об’єкта. Побудовано метамодель рамкового вихрострумового перетворювача з об’ємною структурою системи збудження. Прийнятну точність створеної метамоделі отримано шляхом застосування асоціативних нейронних мереж із методами підвищення точності та декомпозиції простору пошуку. Наведено чисельні результати і графічний матеріал, який ілюструє адекватність та інформативність отриманої метамоделі. Розглянуто приклади синтезу систем збудження із використанням сучасних метаевристичних стохастичних алгоритмів пошуку глобального екстремуму. Наведено чисельні результати отриманого розв’язку і графічний ілюстративний матеріал розподілу густини вихрових струмів на поверхні в зоні контролю об’єкта.
АНАЛІЗ І КЛАСИФІКАЦІЯ МЕТРОЛОГІЧНОГО ЗАБЕЗПЕЧЕННЯ ВИМІРЮВАНЬ РЕЛЬЄФУ НАНООБ’ЄКТІВ
Authors: Квасніков Володимир Павлович , Катаєва Марія Олександрівна
Published: June 2021

У статті проведено аналіз наявних методів та засобів вимірювання рельєфу нанооб’єктів і розроблено їх класифікацію на основі принципів використання. Розглянуто основні інформаційні параметри, на яких базується кожний описаний метод, та визначено умови їх найбільш ефективного застосування для вирішення задач вимірювання рельєфу нанооб’єктів. На основі проведеного аналізу було встановлено, що найбільш функціональним та універсальним при вирішенні широкого кола проблем є метод скануючої зондової мікроскопії. Розробленокласифікацію наявних методів скануючої зондової мікроскопії залежно від характеру їх застосування. Доведено, що збільшення кількості методів вимірювання, що використовуються при метрологічному аналізі нанооб’єктів, збільшить надійність і точність результатів вимірювань, і кожний метод забезпечить додаткові інформаційні параметри. Рекомендовано для підвищення точності нановимірювань використовувати методики, побудовані за принципом інтеграції інформації, наданої різними методами.
АВТОМАТИЗАЦІЯ ВИЯВЛЕННЯ ДЕФЕКТІВ МАШИННОГО ОБЛАДНАННЯ ЗАСОБАМИ ВІБРОДІАГНОСТИКИ
Authors: Стахова Анжеліка Петрівна , Квасніков Володимир Павлович
Published: June 2021

В роботі визначено, що актуальною задачею є своєчасне виявлення небезпечного стану механізму. Показано, що вимірювання рівня вібрації машинного обладнання при різних режимах його роботи дає можливість прогнозувати працездатність пристрою протягом терміну експлуатації. В роботі визначено можливі несправності машинного обладнання, в ролі якого виступає навчальний стенд, і складено вібродіагностичну карту, за якою визначаються несправності. Вирішення цієї задачі дає змогу виявляти дефекти обладнання на ранній стадії їх появи з заданою точністю та водночас зменшити витрати на виявлення дефектів, що, в свою чергу, вимагає детального вивчення типових дефектів вібраційного стенду, які визначаються вібродіагностикою.
МЕТОДИКИ ВИЗНАЧЕННЯ ВМІСТУ Δ9-ТЕТРАГІДРОКАНАБІНОЛУ В НАСІННІ КОНОПЕЛЬ МЕТОДОМ ГАЗОВОЇ ХРОМАТОГРАФІЇ: АНАЛІЗ І НАУКОВЕ ОБҐРУНТУВАННЯ
Authors: Шкурдода Сергій Вікторович , Солодовнік Тетяна Володимирівна , Пасічник В’ячеслав Вікторович , Король Костянтин Петрович , Шинкаренко Дмитро Юрійович
Published: June 2021

У статті піддаються предметному аналізу методики рідинно-рідинної екстракції Δ-9-ТГК з конопляного насіння з подальшою їх апробацією й удосконаленням для відділення заважаючих фракцій, насамперед жирів (олій), та з наступною ідентифікацією Δ-9-ТГК методом газової хроматоас-спектрометрії з мас-селективним детектуванням. Апробовано деякі методи рідинно-рідинної екстракції конопляного насіння. Отримані результати досліджень дають змогу визначити наявність Δ-9-ТГК в насінні конопель та продуктах харчування, виготовлених з насіння конопель. Встановлено, що метод екстракції ацетонітрилом з подальшим промиванням гексаном є найбільш ефективним і легко відтворюваним та може бути рекомендованим для якісного визначення Δ-9-ТГК в незначних концентраціях у насінні конопель. Дані дослідження надалі можуть бути використані для кількісного визначення Δ-9-ТГК в насінні конопель та продуктах харчування, виготовлених з насіння конопель, із подальшим визначенням межі детектування (LOD) та межі кількісного виявлення (LOQ) зазначеної речовини, що необхідно для подальшої сертифікації цієї продукції та її експорту.
КРИТЕРІЇ ОПЕРАТИВНОГО МОНІТОРИНГУ БАЗИ ПРОФЕСІЙНИХ КОНЦЕПТІВ КОМПЛЕКСУ АВТОМАТИЗАЦІЇ КЕРУВАННЯ ЕНЕРГОСИСТЕМИ
Authors: Моркун Володимир Станіславович , Котов Ігор Анатолійович
Published: June 2021

Статтю присвячено проблемі розробки критеріїв оперативного моніторингу й оцінювання ефективності інтелектуальної системи підтримки рішень для протиаварійного керування режимами енергосистем на основі використання професійних концептів і спеціалізованих тезаурусів. Запропоновано критерії розрахунку оперативності використання професійних концептів тезауруса знань про автоматизацію ліквідації аварій в енергосистемі. Наукова новизна полягає в розробці та застосуванні коефіцієнтів ефективності тезауруса професійної лексики, що ґрунтуються на поданні професійних концептів знань про ліквідацію аварій в енергосистемі. Отримані показники дають можливість оцінювати ступінь професійності й ефективності лінгвістичного корпусу і будувати продуктивні бази знань. На відміну від існуючих підходів до побудови баз знань, запропонований підхід дає змогу уніфікувати проектування систем підтримки прийняття рішень та скоротити час їх реалізації.Практичне значення одержаних результатів полягає в оцінюванні ефективності використання професійних знань для побудови уніфікованих інтелектуальних систем підтримки рішень в галузі протиаварійного керування енергосистемами. Результати роботи полягають у забезпеченні оперативного моніторингу ефективності використання бази знань професійних концептів термінів і сленгу. Запропонована модель оцінювання ефективності професійноготезауруса базується на відношенні інтенсивностей зростання загального та спеціалізованого професійного тезаурусів. Результати досліджень доводять зростання ефективності професійних тезаурусів при переході до більш специфічних спеціалізованих науково-технічних галузей.
ІНФОРМАЦІЙНА ТЕХНОЛОГІЯ ПАРАМЕТРИЧНОЇ ОПТИМІЗАЦІЇ РЕЖИМІВ АВТОМАТИЗОВАНОГО ЛАЗЕРНОГО ЗВАРЮВАННЯ В УМОВАХ НЕВИЗНАЧЕНОСТІ
Authors: Гардер Дмитро Андрійович
Published: June 2021

В роботі запропоновано підвищення ефективності інформаційної технології параметричної оптимізації режимів автоматизованого лазерного зварювання тонкостінних конструкцій зі сталі в умовах невизначеності шляхом розробки інформаційної спеціалізованої бази даних за результатами експериментальних параметричних досліджень, створення інформаційної технології аналітичного опису функціональних залежностей між шириною зварного шва, швидкістю переміщення лазерного випромінювання щодо оброблюваної заготовки і потужністю лазерного випромінювання. Запропоновано принцип прийняття рішення параметричної оптимізації в умовах невизначеності на базі розробленого графоаналітичного методу. Метод використовує графічне зображення сплайн-функцій, побудованих в єдиному квадранті із загальною абсцисою, значення якої відповідає величинам зварного шва. Координати точки перетину функціональних залежностей визначають відповідні оптимальні параметри режиму автоматизованого лазерного зварювання тонкостінних конструкцій зі сталі. Візуалізація принципу параметричної оптимізації в умовах невизначеності прискорює процес технологічної підготовки виробництва, що сприяє підвищенню продуктивності підприємства.
TTZ-SOUTH seismic experiment
Authors: Janik T. , Starostenko V. , Aleksandrowski P. , Yegorova T. , Czuba W. , Środa P. , Murovskaya A. , Zajats K. , Kolomiyets K. , Lysynchuk D. , Wуjcik D. , Mechie J. , Głuszyński A. , Omelchenko V. , Legostaeva O. , Tolkunov A. , Amashukeli T. , Gryn D. , Chulkov S.
Published: June 2021

The wide-angle reflection and refraction (WARR) TTZ-South transect carried out in 2018 crosses the SW region of Ukraine and the SE region of Poland. The TTZ-South profile targeted the structure of the Earth’s crust and upper mantle of the Trans-European Suture Zone, as well as the southwestern segment of the East European Craton (slope of the Ukrainian Shield). The ~550 km long profile (~230 km in Poland and ~320 km in western Ukraine) is an extension of previously realized projects in Poland, TTZ (1993) and CEL03 (2000). The deep seismic sounding study along the TTZ-South profile using TEXAN and DATA-CUBE seismic stations (320 units) made it possible to obtain high-quality seismic records from eleven shot points (six in Ukraine and five in Poland). This paper presents a smooth P wave velocity model based on first-arrival travel-time inversion using the FAST (First Arrival Seismic Tomography) code. The obtained image represents a preliminary velocity model which, according to the P wave velocities, consists of a sedimentary layer and the crystalline crust that could comprise upper, middle and lower crustal layers. The Moho interface, approximated by the 7.5 km/s isoline, is located at 45—47 km depth in the central part of the profile, shallowing to 40 and 37 km depth in the northern (Radom-Łysogуry Unit, Poland) and southern (Volyno-Podolian Monocline, Ukraine) segments of the profile, respectively. A peculiar feature of the velocity cross-section is a number of high-velocity bodies distinguished in the depth range of 10—35 km. Such high-velocity bodies were detected previously in the crust of the Radom-Łysogуry Unit. These bodies, inferred at depths of 10—35 km, could be allochthonous fragments of what was originally a single mafic body or separate mafic bodies intruded into the crust during the break-up of Rodinia in the Neoproterozoic, which was accompanied by considerable rifting. The manifestations of such magmatism are known in the NE part of the Volyno-Podolian Monocline, where the Vendian trap formation occurs at the surface.
P-velocity of the upper mantle
Authors: Gordienko V.V. , Gordienko L.Ya.
Published: June 2021

The authors have constructed models featuring seismic P-wave velocity distribution in the upper mantle beneath oceanic, continental and transition regions, such as mid-ocean ridges, basins, trenches, island arcs, and back-arc troughs, Atlantic transitional zones, flanking plateaus of mid-ocean ridges, platforms, geosynclines, rifts, recent activation zones. The models are in agreement with the deep-seated processes in the tectonosphere as predicted in terms of the advection-polymorphism hypothesis. The models for areas of island arcs and coastal ridges are similar to those for alpine geosynclines disturbed by recent activation. The models for areas of mid-ocean ridges and back-arc troughs are identical. They fit the pattern of recent heat-and-mass transfer in the case of rifting, which, given the basic crust with continental thickness, leads to oceanization. The model for the basin reflects the effect of thermal anomalies smoothing beneath mid-ocean ridges or back-arc troughs about 60 million years later. The model for the trench and flanking plateau reflects the result of lateral heating of the mantle’s upper layers beneath the quiescent block from the direction of the island arc and basin (trench) and mid-ocean ridge and basin (flanking plateau).

A detailed bibliography on regions covered by studies was presented in the authors’ earlier publications over past eight years. There are quite significant differences between models for regions of the same type that are described in publications of other authors. This is largely due to the fact that individual authors adopt a priori concepts on the velocity structure of the upper mantle.

High variability of seismic P-wave velocities within the subsurface depth interval has been detected as a result of all sufficiently detailed studies. This variability is responsible for the sharp increase in the scatter of arrival times of waves from earthquakes at small angular distances. The corresponding segments of travel-time graphs were simply ignored, and the graphs started from about 3° after which the scatter of arrival time acquired a stable character. Accordingly, velocity profiles were constructed, as a rule, starting from depths of about 50 km. The constructed velocity profiles vary little from region to region with the same type of endogenous regimes. This enables us to maintain that the models represent standard (typical) VP distributions in the mantle beneath the regions, just as presumed in terms of the theory.
On the unusual properties dielectric constant of the electric field of the free atmosphere
Authors: Bilyi T.A.
Published: June 2021

On the basis of experimental data vertical distribution electric field strength of the atmosphere, the applied problem of fitting constants in the model of the average self-consistent electric field is solved.The model is based on the nonlinear Poisson equation. Such an approach is not trivial because generally known in meteorology interpolation exponential function describing the empirical distribution of the electric field, space charge density and conductivity with a height not quite correctly reproduce a stable stratification of the electric field. Since aircraft measurements are carried out in a natural environment, the dielectric constant is lost, which leads to underestimated values of the electron-ion concentration.This is due to the fact that the potential in situ is screened and the Gauss theorem does not hold for it, and if it does, then for the radius of the Gaussian sphere it is less than the Debye screening radius. For a large Gaussian sphere, only the near-wall part of the electrometer is experimentally determined, and the shielded (inner) part does not contribute to the field flux through the surface by the dynamic screening of the electron. The magnitude of the screening of electrons in air is very large due to the dynamic polarizability of the medium and consists of two parts — the Debye and ion-plasma screening spheres. This, in turn, requires a redefinition of the dielectric constant for correct reproduction of field measurements. Thus, the verification of the dielectric constant was carried out on different experimental data, and its values lie within the same limits as the values obtained from the classical relations of Penn, Debye, and Landau.
The effectiveness of plant-based nutrition in the treatment of arterial hypertension
Authors: Rusnak I. , Slyvka N. , Kulachek V. , Kulachek Y.
Published: June 2021

In the treatment of hypertension, an important role is played by the modification of the lifestyle of patients, especially the correction of their diet. Plant nutrition has the ability to improve blood pressure in such patients. However, a large number of types of vegetarian diets leave open the question of which of them is the best in the treatment of arterial hypertension.The aim of the study was to analyze the literature on the effectiveness of different plant-based diets in the treatment of hypertension and to determine whether the complete absence of animal products in a vegetarian diet is necessary to achieve a significant beneficial effect on blood pressure. The paper analyzes the data of many scientific studies and meta-analyses: the team of scientists from the University of Warwick; Dietary Approaches to Stop Hypertension (DASH) research group; a prospective study of coronary risk in young adults (Coronary Artery Risk Development in Young Adults, CARDIA); analysis of three prospective cohorts - Nurses 'Health Study I (NHS I), Nurses' Health Study II (NHS II), and Health Professionals Follow-up Study (HPFS); calibration sub-study Adventist Health Study-2 (AHS-2). The most common plant-based diets and their effect on blood pressure were analyzed: high-fruit and vegetable diet, high-fiber diet, Nordic, lacto-ovo-vegetarian, Mediterranean, vegan and DASH diets. All scientists confirm a positive correlation between the consumption of animal meat and the risk of developing hypertension and/or difficulties in its treatment.Conclusion. The study of literature data allows us to conclude about the important role of plant foods in the prevention and treatment of hypertension. The best results in lowering blood pressure were demonstrated by diets with a complete absence of animal products.
Immunohistochemical study of trophoblast cells using abortion material in the gestation period 9-12 weeks of pregnancy in women against the background of inflammatory diseases of the female genital organs
Authors: Hoshovska A. , Davydenko I. , Yasnikovska S. , Tesliuk A. , Panchenko O.
Published: June 2021

Abstract. This article is devoted to the results of studies of trophoblast during the gestation of 9-12 weeks. This study is a fragment of a series of immunohistochemical studies of trophoblast with TORCH infection, which are scheduled to be carried out at different gestational dates. Purpose of the study – in various types of trophoblast using the immunohistochemical method to establish the features of the expression of metalloproteinase-2 using abortion material in gestation period 9-12 weeks of pregnancy with TORCH infection compared with observations without an infectious process. Material and methods. The main group of the study consisted of 24 observations of TORCH infection, and the control group - 22 observations of an aborted pregnancy without signs of an infectious process (abortion for social reasons). The study examined abortion material 9-12 weeks of gestation. The method of microdensitometry in a specialized computer program ImageJ evaluated the optical density of the color, and an immunohistochemical procedure was performed on metalloproteinase-2 with primary antibodies and a polymer antigen imaging system using DAKO diaminobenzidine. Results. According to the results of immunohistochemical studies using computer microdensitometry at a gestational age of 9-12 weeks, the very expression of metalloproteinase-2 is observed in the invasive trophoblast, the smallest - in the syncytotrophoblast of the choric villi, both with TORCH infection and without an infectious process, and intermediate values are noted in chorionic villus cytotrophoblast and cell column cytotrophoblast. Infection, the expression of metalloproteinase-2 is reduced in all four types of trophoblast (cytotrophoblast of chorionic villi; cytotrophoblast of cell columns; invasive cytotrophoblast in endometrial fragments), with TORCH except for syncytotrophoblast of chorionic villi. Conclusions. According to the results of immunohistochemical studies using computer microdensitometry at a gestational age of 9-12 weeks, both with TORCH infection and without an infectious process, the largest expression of metalloproteinase-2 is observed in invasive trophoblast, the smallest - in the syncytiotrophoblast of chorionic villi, and intermediate indices are noted in the cytotrophoblast of chorionic villi and the cytotrophoblast of cell columns. The expression of metalloproteinase-2 decreases in all types of trophoblast with TORCH infection, excluding the syncytiotrophoblast of chorionic villi.
Load Switching Analysis using Converter with Optimization Algorithm in Hybrid Renewable Energy System
Authors: Bharti Shilpa , Dubey Abhishek
Published: June 2021

Recently, an increasing number of organizations have begun to view renewable energy and industries as opportunities rather than regulations in the context of their production, distribution, and services. In this paper, main objective of designing a grid integrated solar-wind hybrid energy system for driving loads for improving its reliability and efficiency. And the inverter control designing with an AI-based optimization algorithm to attain improved active power at the terminal of loading by reducing the losses. And Improvement in the reactive power output from the system by the inverter control by a designed hybrid system that can compensate the reactive power requirement when required. The active power output from the system has enhanced to 77860 W in the system having converter regulated from the proposed controller that is MF_DEH from 77230 as a result of improved performance and reduced losses. The system was first compared with the PI-directed inverter control and the THD% in current, as well as voltage waveform, was found to be reduced to 0.11% in voltage and 0.41% in current from 0.86% and 1.93% respectively.
Formation of personal stability of a tennis player in the process of training
Authors: Budyakova Tatyana Petrovna , Baturkina Galina Viktorovna
Published: June 2021

Substantiate a program for correcting negative and other ineffective attitudes in the process of table tennis training. The research material was negative and ineffective attitudes, as well as positive attitudes, a list of which was obtained during the first stage of the study using the autobiographical method and the method of expert assessments. The experts were 19 tennis players participating in regional and local competitions.  At the second stage of the study, an experiment was conducted to correct negative and form positive attitudes with members of the tennis sports section of Bunin Yelets State University, for people. After the implementation of the program for correcting negative attitudes, its effectiveness was proved. The share of negative attitudes was significantly reduced; the place of negative attitudes was replaced by positive, productive attitudes. The implementation of the program showed that psychological training in the form of a readiness to demonstrate an anti-victim style in relations with rivals also allows increasing overall performance during training games when time is not wasted on unnecessary experiences of failure.
Abbreviation in korean cyber communication
Authors: Egorova Kyunney , Ahn Sang-Cheol
Published: June 2021

The purpose of this paper is to argue that the various patterns of the Korean abbreviations should be interpreted as cultural icons. Leading approach to research: classification by types of abbreviations and theoretical analysis of their properties. The authors argue that the phonetic but also graphic nature of the Korean alphabet system makes the structure very innovative and unique. Moreover, the authors claim that along with the common borrowing of English abbreviations, the typological differences in writing produce unique abbreviations patterns, especially in Korean. As for the theoretical analyses, we take the examples from various papers on neologism and the online dictionaries. The theoretical significance of the work lies in the fact that the abbreviated expressions are considered as a unique tool of modern communication, especially for the young generation. In this regard, this study can also contribute to the typological research on writing systems. From a practical point of view, the result of this study can serve a reference material as well as a good basis for subsequent research on coinage of neologism.