bluuebunny/crossref_metadata_2025 huggingface dataset:
Open pelvic fractures – results of a multi-institutional study
Authors: Mladenovic Marko , Stoiljkovic Predrag , Lalic Ivica , Harhaji Vladimir , Krstic Andrija
Published: June 2021

Open pelvic fractures are devastating injuries, rare, and with high
mortality. Leading causes of mortality are: haemorrhage, infection and
associated injuries. The aim of this paper is to point out methods of
treating these injuries and great number of prognostic mortality factors.
Material - in period from January 2011 to December 2015, 221 patients with
pelvis ringfracture were treated in three large clinical centers of Serbia,
of which 13(5%) had an open fracture type. We have classified pelvic ring
fractures according to the Young - Burgess classification. We have
classified injuries according to Gustilo at I, II, and III degree, and the
location of the wound according to Faringer classification was distributed
in zone I, II and III. Urogenital and intra-abdominal injuries were
monitored, and severity of injuries was determined according to Severity
Score Injury (ISS) and Trauma Score (TS). Results - there were 6(46%) women
and 7(54%) men at the average age of 41(13 - 76). Injuries from traffic
trauma are dominant. The most common cause of pelvic ring fracture is an
anterior posterior compression - 6(46%), lateral compression - 4(31%) and
vertical force in 3 (23%) patients. Dominant injuries are type I and II
according to Gustilo, and zone I according to Faringer classification. There
were 6 (46%) patients with urogenital injuries, and the same number with
intra-abdominal injuries, of which 3(23%) patients have been treated with
colon resection and diversion. Due to abundant hemorrhage and hypovolemic
shock 2 patients died, and another one died after three days due to sepsis
and multisystem organ failure (MSOF). Conclusion - Open pelvic fractures
have high mortality rate, due to: haemorrhage, infection, associated
abdominal and genitourinary tract injuries, ISS> 25, TS <8 and age of
patient >65 years.
MEK/ERK Signaling in β Cells Bifunctionally Regulates β-cell Mass and Glucose-stimulated Insulin-secretion Response to Maintain Glucose Homeostasis
Authors: Ikushima Yoshiko Matsumoto , Awazawa Motoharu , Kobayashi Naoki , Osonoi Sho , Takemiya Seiichi , Kobayashi Hiroshi , Suwanai Hirotsugu , Morimoto Yuichi , Soeda Kotaro , Adachi Jun , Muratani Masafumi , Charron Jean , Mizukami Hiroki , Takahashi Noriko , Ueki Kohjiro
Published: June 2021

In diabetic pathology, insufficiency in β-cell mass
unable to meet peripheral insulin demand and functional defects of individual β
cells to produce insulin are often concurrently observed, collectively causing hyperglycemia.
Here we show that the phosphorylation of ERK1/2 is significantly decreased in
the islets of db/db mice as well as
in those of a cohort of subjects with type 2 diabetes. In mice with abrogation
of ERK signaling in pancreatic β cells through deletion of Mek1 and Mek2, glucose
intolerance aggravates under high-fat diet-fed conditions due to insufficient
insulin production with lower β-cell proliferation and reduced β-cell mass,
while in individual β cells dampening of the number of insulin exocytosis
events is observed, with the molecules involved in insulin exocytosis being less
phosphorylated. These data reveal bifunctional roles for MEK/ERK signaling in β
cells for glucose homeostasis, i.e., in regulating β-cell mass as well as in
controlling insulin exocytosis in individual β cells, thus providing not only a
novel perspective for the understanding of diabetes pathophysiology but also a potential
clue for new drug development for diabetes treatment.
Diabetic Ketoacidosis and Mortality in People With Type 1 Diabetes and Eating Disorders
Authors: Gibbings Nicole K. , Kurdyak Paul A. , Colton Patricia A. , Shah Baiju R.
Published: June 2021

Objective: To determine the risk of diabetic ketoacidosis (DKA) and
all-cause mortality among adolescents and young adults with type 1 diabetes
with and without an eating disorder.

Research Design
and Methods: Using population-level healthcare administrative data covering the
entire population of Ontario, Canada, all people with type 1 diabetes aged 10
to 39 as of January 2014 were identified. Individuals with a history of eating
disorders were age/sex matched 10:1 with individuals without eating disorders. All
individuals were followed for 6 years for hospitalization/emergency department
visits for diabetic ketoacidosis, and for all-cause mortality.

Results: We
studied 168 people with eating disorders and 1680 age/sex-matched people
without eating disorders. Among adolescents and young adults with type 1
diabetes, 168 (0.8%) had a history of eating disorders. The crude
incidence of diabetic ketoacidosis was 112.5 per 1,000 patient-years in people
with eating disorders, versus 30.8 in people without eating disorders. After
adjustment for baseline differences, the subdistribution hazard ratio comparing people with and without
eating disorders was 3.30 (95% confidence interval 2.58-4.23, p<0.0001).
All-cause mortality was 16.0 per 1,000 person-years in people with eating
disorders, versus 2.5 in people without eating disorders. The adjusted hazard
ratio was 5.80 (95% confidence interval 3.04-11.08, p<0.0001).

Conclusions: Adolescents
and young adults with type 1 diabetes and eating disorders have more than
triple the risk of diabetic ketoacidosis and nearly 6-fold increased risk of
death compared to their peers without eating disorders.
Lacan, linguística e antropologia: consolidação e contribuições
Authors: Rios Cleusa
Published: June 2021

Entrevista com Cleusa Rios Passos, professora titular da Faculdade de Filosofia Letras e Ciências Humanas da Universidade de São Paulo, que tem experiência na área de Letras, com ênfase em Teoria Literária, atuando principalmente nos seguintes temas: Guimarães Rosa, estudo das formas narrativas e confluências entre crítica literária e psicanálise. Desde 2005, coordena (com outro docente) o grupo de pesquisa "Crítica Literária e Psicanálise". Entrevista: Elisabeth CardosoEdição: Ana Paula Rodrigues da Silva, Thiago Fonseca (TV-PUC)Música: PIPA estúdio
Тhermodynamic properties solutions 5-(nitrophenyl)-furan-2-carboxylic acid in ethyl acetate
Authors:   Lviv Polytechnic National University, Sobechko І.B. , Gorak Yu.I. ,   Ivan Franko National University of Lviv, Dibrivnyi V. M. ,   Lviv Polytechnic National University, Klachko O. R. ,   Lviv Polytechnic National University, Kostyuk R. R. ,   Lviv Polytechnic National University
Published: June 2021

According to the temperature dependence of the solubility of 5-(2-nitrophenyl)-furan-2-carboxylic acid, 5-(3-nitrophenyl)-furan-2-carboxylic acid and 5-(4-nitrophenyl)-furan-2-carboxylic acid, in the values of enthalpy and entropy of their dissolution were calculated in ethyl acetate. Taking into account the enthalpy and entropy of melting listed up to 298 K, the enthalpies and entropies of mixing are calculated. The dependence of the solubility of carboxyl-containing substances at 298 K on their melting point was established.
Рotentiometric and conductometric determination of amine and acid numbers of reaction mixture from fatty acid amidation
Authors:   Lviv Polytechnic National University, Poliuzhyn I. P. , Tsiupko F. I. ,   Lviv Polytechnic National University, Laruk M. M. ,   Lviv Polytechnic National University, Yurin O. O. ,   Lviv Polytechnic National University, Guminilovych R. R. ,   Lviv Polytechnic National University
Published: June 2021

The possibility of simultaneous potentiometric and conductometric titration is considered for determination of the acid (A.N.) and amine (AM.N.) numbers of the amidation reaction mixture for technical fatty acids (F.A.) by diethylenetriamine (DETA). Interpretation of titration curves was performed on the basis of model mixtures for DETA and F.A. industrial sample. The obtained results indicate the possibility of determining A.N. and AM.N. values by sequential titration of one sample for industrial organic products and amidation reaction mixtures.
Normal phase thin layer chromatography for aromatic derivatives of 3-chloro-1,4-naphtochinone
Authors:   Lviv Polytechnic National University, Smirnova O. Ya. , Yatchyshyn Yo. Yo. ,   Lviv Polytechnic National University, Kolobych S. V. ,   Lviv Polytechnic National University, Poliuzhyn I. P. ,   Lviv Polytechnic National University
Published: June 2021

The chromatographic characteristics were investigated for eight aromatic derivatives of 3-chloro-1,4-naphthoquinone under conditions of normal-phase thin-layer chromatography for benzene-based binary mobile phase and such polar solvents as chloroform, acetone, acetonitrile, methanol and propan-2-ol. The slope of linear retention dependencies for the investigated compounds on the concentration of the polar component in the mobile phase satisfactorily correlates with the area occupied by the adsorbed analyte molecule in the stationary phase. The intercept in the Soczewinski equation depends on the polar component of the mobile phase.
Transesterification of sunflower oil’s triglycerides by aliphatic alcohols С1–С4
Authors:   Lviv Polytechnic National University, Melnyk Yu. R. , Melnyk S. R. ,   Lviv Polytechnic National University, Bezdil V. V. ,   Lviv Polytechnic National University, Mahorivska H. Ya. ,   Lviv Polytechnic National University
Published: June 2021

Transesterification of sunflower oil triglycerides by C1-C4 aliphatic alcohols in the presence of cation exchange resin KU-2-8 with immobilized divalent metal ions has been studied. It was found that the reaction occurs at a high initial rate and the conversion of triglycerides for 180 min in presence aliphatic alcohols C1– C3 is 88.4-99.8 %. It is shown that under these conditions the rate of transesterification reaction of triglycerides with butan-1-ol is significantly lower and the conversion achieved in 180 min does not exceed 52.3 %.
Antioxidant activity of heterocyclic amino containing derivatives of naphthoquinone and their compositions with surface-active rhamnolipids
Authors:   Lviv Polytechnic National University, Polish N. V. , Marintsova N. G. ,   Lviv Polytechnic National University, Karkhut A. I. ,   Lviv Polytechnic National University, Yaremkevysh O. S. ,   Lviv Polytechnic National University, Karpenko O. V. ,   Lytvynenko Institute of Physicoorganic and Coal Chemistry Ukrainian
Published: June 2021

Composite preparations based on heterocyclic amine-containing naphthoquinone derivatives and surfactant rhamnolipids were obtained. The intensity of the processes of lipid peroxidation (LPO), oxidative modification of proteins (OMB) and radical-absorbing activity against 1,1-diphenyl-2-picrylhydrazyl (DFPG) was studied. Compounds exhibiting high antioxidant activity against LPO and OMB processes were identified, namely: 2-[(6-(4-fluorophenyl-5-oxo-2,5-dihydro-1,2,4-triazin-3-yl) phenyl)amino]naphthalene-1,4-dione 1d and its composite preparation with rhamnolipid 1d + RL. It was found that all synthesized compounds show antioxidant activity in LPO processes.
Determination of qualitative characteristics of soybean and rapeseed oil by infrared spectroscopy
Authors:   Lviv Polytechnic National University, Hlukhaniuk A. R. , Ivashchuk O. S. ,   Lviv Polytechnic National University, Khomyak S. V. ,   Lviv Polytechnic National University, Chyzhovych R. A. ,   Lviv Polytechnic National University, Kuzminchuk T. A. ,   Lviv Polytechnic National University, Semenyshyn Ye. M. ,   Lviv Polytechnic National University
Published: June 2021

The article presents results of the study of soybean and rapeseed vegetable oils’ qualitative composition dependence on the degree of raw materials grinding obtained by extraction in a stationary layer in a Soxhlet apparatus using methylene chloride as a solvent. A number of experiments were performed to determine the optical properties of oil by infrared spectroscopy. The absorption spectra for different oil samples are present in the article. The obtained results were compared with previous refractometric and UV-Vis spectroscopy studies.
Оbtaining isovaleric acid extraction from plant raw material
Authors:   Lviv Polytechnic National University, Dyachok V. V. , Dіachok I. L. ,   Danylo Halytsky Lviv National Medical University, Ivankiv O. L. ,   Danylo Halytsky Lviv National Medical University
Published: June 2021

The paper presents a mathematical description of the process of obtaining isovaleric acid by the method of extraction of roots and rhizomes of valerian, taking into account its chemical structure and the nature of the extractant. The traditional case of the extraction process, the straight line of equilibrium in the case of using an aqueous alcohol solution as an extractant and the unconventional case of using desalinated water as an extractant, which is represented by a convex equilibrium line, is substantiated. The cause of the unconventional case is the phenomenon of formation of associations between diphilic molecules of isovaleric acid and dipole molecules with water. The possibility of using ion exchange was investigated to isolate isovaleric acid from the extract of biologically active compounds. The identity of isovaleric acid obtained in this way by the gas method was confirmed chromatography.
Influence of polystyrene modifier on features of polyvinylchloride plastics production
Authors:   Lviv Polytechnic National University, Katruk D. S. , Masyuk A. S. ,   Lviv Polytechnic National University, Levytskyi V. Ye. ,   Lviv Polytechnic National University
Published: June 2021

The main methods of physical modification of PVC materials is the combination with other polymers, including PS plastic, and the creation of polymer (nano) composites containing metal and silicate fillers. Modification of polyvinyl chloride by polystyrene plastic leads to obtain materials with reduced degree of plasticizer release out of matter volume, adjustable elastic-plastic characteristics, and enhanced physico - mechanical and thermal properties. Physical modification of vinyl chloride polymers by other polymers or nanoscale particles of inorganic nature enables predictable affect on the morphology of these materials and directed regulate their technological and performance properties.
ANALISIS PERFORMANSI TURBIN PROPELLER OPEN FLUME TIPE TC 60 KAPASITAS 100 W TERHADAP PERUBAHAN DEBIT
Authors: Sugandi Wahyu K , Kendarto Dwi R , Dwiratna Sophia , Rahmanda Arif
Published: June 2021

The TC 60 open flume propeller turbine is an example of a pico-hydro-based fluid engine. The potential of the TC 60 open flume propeller turbine can be maximized by paying attention to the flow rate. This study aims to analyze the performance of the TC 60 open flume propeller turbine performance which is influenced by changes in discharge. The method used is descriptive analysis method. The turbine performance testing was carried out at the CV Cihanjuang Inti Teknik laboratory in Cimahi. Turbine testing begins by making 9 discharge ranges from 1.28 litre/sec until 4.85 litre/sec then testing each of these flows. Power testing is carried out using a lamp load of 10 to 100 watts. The results showed the effect of changes in discharge on the power generated by the turbine. The maximum power produced in this study is 74 watts at a discharge flow of 4.85 litre/sec with a load of 70 watts. The lowest discharge to be able to move the turbine is 1.28 litre/ sec. The results of the technical feasibility analysis on civil buildings in CV Cihanjuang Teknik show that the TC 60 open flume propeller turbine is feasible to use by considering the design of the discharge, head and channel shape of civil buildings. Keywords: discharge, picohydro, propeller turbine, performance
ANALISIS FAKTOR PRIORITAS PENGEMBANGAN KOMODITAS PERKEBUNAN UNGGULAN DENGAN METODE AHP (ANALTYCAL HIERARCHY PROCESS
Authors: Herdhiansyah Dhian , Sudarmi Sudarmi , Sakir Sakir , Asriani Asriani
Published: June 2021

This study aims to determine the priority factors in the development of plantation commodities, including cocoa, coffee, coconut, and oil palm as substitutes in East Kolaka District-Southeast Sulawesi.The method used is the analytic hierarchy process (AHP) of expert choice software 11. The AHP method includes: (a) developing a hierarchy; (b) determining priorities, and (c) calculating the consistency ratio (CR).  The consistency ratio test (CR) of Expert Choice 11software on priority factors in the development of leading plantation commodities was obtained from each resource person (informant) from: (a) the Department of Agriculture; (b) Plantation Service; (c) Trade, Industry, Small and Medium Enterprises Office; (d) traders; (e) Gapoktan; (f) banking, and (g) academics. The study shows acceptable or consistent results because of CR<0.100. AHP analysis indicates that the priority factors for developing superior plantation commodities in East Kolaka Regency include: (a) feasible for business development (LBPB) 26.7%; (b) contribution of community income (KPM) 18.0%; (c) Added value (NT) 13.3%; (d) local government policies (KPD) 11.0%; (e) land suitability (KL) 10.5%; (f) market orientation (OP) 10.7%; and (g) non-conformance with environmentally friendly standards (RL) 9.7%. Keywords: analytical hierarchy process (AHP), expert choice 11, superior plantation commodities
ОПТИМІЗАЦІЯ РОЗРАХУНКУ ТЕМПЕРАТУРИ ТА ШВИДКОСТІ ДЛЯ ТЕПЛООБМІННИХ ПРОЦЕСІВ В АДІАБАТИЧНИХ УМОВАХ
Authors: Онищук Оксана Олександрівна
Published: June 2021

У статті показано модель теплообміну для циліндричної заготовки з нестаціонарним режимом в адіабатичних умовах. Визначено середню швидкість поширення тривимірного фронту теплообміну вздовж циліндра та середню поперечну температуру для цього режиму через рівняння теплопровідності та рівняння кінетики. Крім того, визначено вплив радіуса ци-ліндра на швидкість теплообміну. Використовуючи рівняння теплопровідності та граничні умови, визначено середню поперечну температуру циліндра при теплообміні. Також викорис-товуючи рівняння кінетики, отримуємо значення середньої швидкості поширення тривимірно-го фронту вздовж циліндра для нестаціонарного режиму в адіабатичних умовах. Досліджено через параметр R0, який показує, наскільки радіус циліндра більший характеристичної величи-ни зони реакції, що при збільшенні радіуса швидкість теплообміну незначно зменшується. Графічно показано залежність R0 від характеристичної величини зони реакції G/Td для двох режимів ступеня віддалення від області. Використовуючи рівняння теплопровідності та рів-няння кінетики з початковими і граничними умовами, визначено середню швидкість поширен-ня фронту вздовж циліндра для нестаціонарного режиму в адіабатичних умовах та середню поперечну температуру. Розв’язано осесиметричну граничну задачу нестаціонарного теплооб-міну з рухом фронту тепла уздовж осі симетрії циліндра. Приведена математична модель теплообмінного процесу досліджувалася із застосуванням методу кінцевих різниць і програм-ного забезпечення ANSYS. Показано, що температура глибини перетворення теплообміну зна-ходиться в перерізі, перпендикулярному осі циліндра, який проходить через точку з максималь-ною температурою, причому, чим вища температура, тим світліша штриховка області.
МЕТОД ВИЯВЛЕННЯ І ЗБЕРЕЖЕННЯ НЕПОДІЛЬНОЇ СЕМАНТИЧНОЇ СКЛАДОВОЇ АНГЛОМОВНОГО МАНІПУЛЯТИВНОГО ТЕКСТУ ПРОПАГАНДНОГО ДИСКУРСУ НА ОСНОВІ КВАНТОВОГО ФОРМАЛІЗМУ
Authors: Тарасенко Ярослав Володимирович
Published: June 2021

У статті проведено дослідження особливостей використання квантового формалізму в задачах комп’ютерного аналізу та обробки маніпулятивних текстів. Розроблений метод виявлення і збереження неподільної семантичної складової маніпулятивного тексту пропагандного дискурсу дає можливість підвищити ефективність виявлення і збереження неподільної семантичної складової порівняно з методами семантичного стиснення, що базуються на інформаційній ентропії тексту, що дає змогу виокремити та зберегти ключові індивідуальні семантичні конструкції, притаманні психолінгвістичному портрету зловмисника для подальшого впровадження в них зворотного впливу. Змодельовано роботу системи визначення ремиманіпулятивного англомовного тексту та проведено порівняння з результатами роботи систем семантичного стиснення, що доводить можливість подолання межі семантичного стиснення. Попередні експериментальні дані дають змогу стверджувати про високу ефективність розробленого методу. Окреслено перспективи використання подібного методу в процесі забезпечення інформаційної безпеки.
ПОРІВНЯННЯ ПРЯМОТОЧНОЇ І ВИТІСНЮВАЛЬНОЇ БІОФІЛЬТРАЦІЇ В ПРИСТРОЯХ ДЕЦЕНТРАЛІЗОВАНОГО ОЧИЩЕННЯ ВОДИ
Authors: Гевод Віктор Сергійович , ЧЕРНОВА АНАСТАСІЯ СЕРГІЇВНА , ІСАЄВА АКМАРАЛ УМІРБЕКОВНА
Published: June 2021

Денітрифікація питної води досліджена методами прямоточної і витіснювальної біо-фільтрації в спеціально розроблених малогабаритних фільтруючих пристроях, призначених для систем децентралізованої водопідготовки. Показано, що заміна прямоточного режиму біо-фільтраційної денітрифікації на витіснювальний має суттєві переваги. Зникає необхідність використовувати периферійне обладнання для підтримки безперервного, повільного протоку води крізь біофільтр. Споживач отримує можливість періодично подавати великі порції води в біофільтр і синхронно отримувати таку ж кількість денітрифікованої води. Ефект досяга-ється шляхом оптимізації конструкції пристрою та структури фільтруючого простору. Конструкція створених біофільтрів проста, для їх складання можуть використовуватися матеріали з мінімальним «вуглецевим відбитком».
Peculiarities of morphogenesis of orbit and organ of vision structures in human fetuses
Authors: Tsyhykalo A. , Kozariichuk N. , Yakovets K. , Kulynych H.
Published: June 2021

The aim of this work is to elucidate the features of morphogenesis, syntopic and morphometric changes in the structures of the orbit, neurovascular and muscular structures of the organ of vision in the fetal period of human ontogenesis.Material and methods. By means of complex of methods of morphological research (anthropometry, morphometry, microscopy, preparation, three-dimensional computer reconstruction and statistical analysis), 30 specimens of human fetuses of both sexes aged from 4 to 10 months of intrauterine development (IUD) (160.0-460.0 mm parietal-coccygeal length (PCL)) were studied. Computer tomography was used to study 17 human fetuses aged from 4 to 9 months of IUD (180.0-440.0 mm PCL).Results. At the end of the 5th month of IUD, an orbital index is 75%, which is noted in the transformation of the shape of orbit from flattened to rounded due to an increase in its vertical size relative to the horizontal one. We associate this transformation of the orbit with syntopic influence of adjacent regions: the growth of the lateral wall of the nasal cavity, development of the paranasal sinuses, and facial skeleton. At the end of the 5th week of intrauterine development, external eyeball muscles are finally differentiated from the common muscle rudiment. The analysis of changes in morphometric parameters of muscles of the eyeball made it possible to derive mathematical functions, that describe normal dynamics of growth of their length, as well as to reveal critical periods of their development in terms of the rate of changes in their thickness and width.Conclusions1. The development of the organ of vision in the fetal period of human ontogenesis is a complex process due to the coordinated interaction between morphological and morphometric changes in the orbit, eyeball and its muscles, nerves and vessels.2. Critical periods of development of the orbit and its structures is the 6th month of intrauterine development, during which there is an uneven growth rate of the size of the muscles of the eyeball, as well as the size of the orbit.3. At the 6th month of intrauterine development, uneven growth rates of the horizontal size of the orbit relative to the vertical one are observed, as a result of which its shape begins to return to the mesoconchal type characteristic of such prefetuses. Such age-related transformations of shape and size of the orbit are due to the growth of the eyeball, skull and face, which generally determines the shape of the orbit.4. Starting from the 8th month of fetal period of development, structure and topography of the structures of the orbit acquire signs of a definitive condition, the shape of the orbit is finally established, and uniform growth rates of all structures of the organ of vision are observed, except for the growth of the circumference of the orbit at the end of prenatal period of human ontogenesis.
On the epidemic situation of tick-borne spotted fevers in Ukraine (literature review)
Authors: Zarichna O. , Loginov Y. , Lozynskyi I.
Published: June 2021

The results of the distribution of rickettsiae of the group of tick-borne spotted fevers in Ukraine are presented. The progress made in the study of rickettsiae is associated with the improvement of methods for their detection and isolation.The purpose of the work. To study the distribution of rickettsiae of the group of tick-borne spotted fever, including the causative agent of Marseille spotted fever, in different regions of Ukraine.Conclusion. The endemicity of rickettsial infections of the group of tick-borne spotted fevers in Ukraine has been proved. Data on new types of vectors and polyvector nature of natural foci were obtained. The circulation of the pathogen of Marseille spotted fever was established by serological monitoring of the total population.
Pathogenetic influence of liver steatosis in patients with hemorrhagic vasculitis: correlation analysis
Authors: Komarytsya O. , Radchenko O.
Published: June 2021

According to own data, 74% of patients with hemorrhagic vasculitis have sonographic signs of liver steatosis, but its influence on clinical and laboratory parameters of vasculitis is not established yet.

The aim – to reveal the pathogenetic links of liver steatosis influence using correlation analysis, which could help in the planning of management strategy.

Matherial and methods. We retrospectively analyzed the data of 50 inpatients with the help of Pearson’s correlation analysis.

Results. In patients with hemorrhagic vasculitis, liver steatosis was more prominent in older ones and in higher body weight patients. Liver steatosis was accompanied by more significant changes in the right ventricle, left atrium, and aorta. It was also associated with systemic inflammation activity, serum proteolytic and thrombotic activity. In patients with liver steatosis, their age – a non-modifiable cardiovascular risk factor – was strongly associated with the deterioration of heart condition and changes of serum proteolytic and thrombotic activity, which, in turn, creates the background for adverse cardiovascular events. Liver steatosis was accompanied by the activation of systemic inflammation, which led to the transformation into steatohepatitis.

Conclusion. The influence onto the liver steatosis is the only way of prevention of cardiovascular events and steatohepatitis in patients with hemorrhagic vasculitis.
Russian musical folklore as a development factor of ethnic self-consciousness of students-musicians in the educational space of a higher educational establishment
Authors: Klimov Vladimir Igorevich , Kirichenko Tatiana Dmitrievna
Published: June 2021

The purpose of this article is to analyze the results of the development of ethnic self-awareness of students-musicians using Russian musical folklore in the educational space of a higher educational establishment. As a result of the study and analysis of the normative legal documents regulating the professional training students-musicians in the direction of training 44.03.05 Pedagogical education (with two training profiles), focus (profile): Music, Additional education; Music, World art culture, the disciplines of the curriculum were determined, and the forms of educational work of young people were identified, contributing to the most effective immersion in the Russian musical tradition, the formation of an environment of ethnic unity, the development of ethnic identity. The conducted research has confirmed the effectiveness of the development of ethnic self-awareness of students-musicians in the educational space of a higher educational establishment using Russian musical folklore. The mechanism for the implementation of this process was the provision of a choice of content and forms of familiarizing students-musicians with folk musical art.
Distance education as a currently topical form of future specialists’ professional training: development problems and prospects
Authors: Bazarova Tatiana Sodnomovna , Kibalnik Alena Vyacheslavovna , Nikitina Elena Vyacheslavovna , Solovyeva Rimma Alekseevna , Fomitskaya Galina Nikolaevna
Published: June 2021

The article deals with a topical problem – the development of distance education in the context of modern society’s digitalization. This problem is considered in view of the growing importance of electronic educational resources (EER) to increase the educational process efficiency through a remote interactive mode. The analysis of the given results helped to highlight the current problems of modern education in a distance format: the lack of contact interaction between the participants, which allows implementing a differentiated approach and solve educational problems; compliance  with the mandatory requirements of distance education by students (student’s rigid self-discipline and high motivation); free access to EER; an increase in the number of independent tasks and the absence of constant feedback from students, etc. To solve the mentioned problems, it is necessary to ensure the organization of the educational process aimed to develop students’ sustainable interest in learning.
Emergencia y crecimiento inicial de festuca alta libre e infectada con endófitos silvestres o seguros
Authors: Petigrosso L.R. , Spagnuolo G. , Vignolio O.R. , Monterubbianesi M.G. , Assuero S.G.
Published: June 2021

El objetivo de este trabajo fue evaluar, durante la etapa temprana de implantación de festuca alta, el porcentaje y la velocidad de emergencia, la producción de biomasa y la proporción de raíz en plantas provenientes de una población naturalizada del sudeste de la Provincia de Buenos Aires (S) y del cv. Taita (T), libres (S- y T-, respectivamente) e infectadas con el endófito silvestre Epichloë coenophiala (S+) y con el endófito seguro AR584 (T+) respectivamente. Se sembraron ocho bandejas plantineras de 50 celdas para cada tratamiento (i.e. S-, S+, T- y T+) y se ubicaron de forma tal que la superficie superior de la misma quedara al ras del suelo en una parcela preparada para la siembra de una pastura. El número de plántulas emergidas en cada bandeja se registró diariamente hasta los 28 días desde la siembra y se determinó el porcentaje y la velocidad de emergencia. A los 47 días desde la siembra se determinó la materia seca de la parte aérea y radical de las plantas emergidas. A los 28 días desde la siembra, no se registraron diferencias significativas en el número de plantúlas emergidas dentro de las festucas infectadas (p=0,9965) ni entre las libres (p=0,7525). No se encontraron diferencias significativas (p=0,4738) entre las festucas en la velocidad de emergencia. Las festucas infectadas presentaron una biomasa total por planta superior a la de las libres debido a una mayor biomasa de raíces, aunque las diferencias para ambas variables sólo fueron significativas (p<0,001) en el caso del cv. Taita. En nuestras condiciones la presencia del endófito aumentó el porcentaje de plántulas emergidas tanto en la población naturalizada como en Taita, y promovió el desarrollo radical en este último.
“It Turns Out Glavlit Has Not Yet Signed Off on Ostrovsky Dictionary…” (Correspondence of N. S. Ashukin and S. I. Ozhegov 1940—1960s)
Authors: Nikitin O. V.
Published: June 2021

The   little-known   factsof the work of N. S. Ashukin, S. I. Ozhegov and V. A. Filippov on the original lexicographic edition  of  the  1940s — “Dictionary   to  the plays of A.  N.  Ostrovsky”  is  analyzed in the article. The connection between the socio-cultural situation in the country and the scientific research of those years is shown. Special attention is paid to the facts of ideological pressure on philological thought. The circumstances that  hindered the publication of the Dictionary are revealed. For the first  time,  genuine  letters   from the participants in this project, telling about the ambiguous situation in Glavlit (Soviet Main Administration for Safeguarding State Secrets in the Press) and the intention of the authors to save the manuscript from death are published in the appendix. It tells about further attempts of scientists and their descendants to resume the preparation of the publication of the book in the  1960—1970s.  The facts given in the correspondence are commented on from the standpoint  of  history  and  philosophy  of science, the necessary references are indicated, possible comparisons are made with the events and persons mentioned in the letters. The presented fragment of the linguistic picture of the world is also considered  in  the  key of the development of linguistic personality and its role in the era of dictatorship. Attention is drawn to the high historical  value of the undertaken work and its place in the lexicographic tradition of the XX century. It is concluded  that archival materials  play a key role in reconstructing the real picture  of the life and activities of Soviet scientists, supplement the chronicle of science with valuable observations and contribute to an objective  assessment  of  the  achievements of philologists, show their firm position in upholding the interests  of  science  during  the dominance of ideologization in society.
Character’s Inner Speech as Effective Way of Literary Discourse Organization (Novel “The Remains of the Day” by Kazuo Ishiguro)
Authors: Lavrova S. Yu. , Ermakova L. A.
Published: June 2021

The article examines the protagonist’s verbalized  inner  speech  in  the   literary   text of the novel “The Remains of the Day” as a way of literary discourse organization by English novelist Kazuo Ishiguro. The  relevance of the study is explained by the interest in   the analysis of the inner speech of characters in a literary text, which differs from the natural inner speech of an individual in the ways of  linguistic  expression,  the  specifics   in the structure of the narrative. It is shown that the study of the inner speech of a character   of literary discourse using such parameters of its measurement as structural-compositional, semantic-conceptual, communicative, allows us to identify the features of the functional role of this type of speech. The novelty of the research lies in the substantiation of how the character's inner speech (introspection), being a significant unit of composition, correlates with prospection and retrospection of the text, acting as the main form of narration. The article elicits four basic concepts that organize the content of the character's inner speech. The authors of the article offer a close analysis of the rheme-theme correlation of the title of the novel and the main text as the basis of the author’s literary discourse. Particular attention is paid to the modality of the character's inner speech from the point of view of the pragmatic orientation of this type of speech towards the addressee-reader and discourse markers that influence the process of discourse interpretation.
Using Online Services to Report a Crime
Authors: MASLENNIKOVA Larisa , VILKOVA Tatyana , SOBENIN Andrew , TABOLINA Kseniia , TOPILINA Tatyana
Published: June 2021

The purpose of the study is to analyze the Russian and foreign experience in the introduction of online services for reporting crime and substantiate proposals for improving effective communication between the state and the population in the context of the development of digital technologies.

The features of online services for filing crime reports of various leading states in the field of e-government development are considered. The general trends and limits of the use of online services for filing a crime report in electronic form are revealed:1) the possibility of handling such a report only in cases that do not require an immediate response from law enforcement officials; 2) a limited number of categories of crimes for which an electronic crime report can be made; 3) the identification of the applicant both through national portals of public services, and without mandatory identification and authentication; 4) an electronic warning to the applicant about the responsibility for providing deliberately false information; 5) the ability to attach various materials to the application, including a video recording of the crime, data about the person who committed the crime, and other information.

The conclusion is justified that the introduction of electronic crime reports should complement the ability to directly report a crime to the police, and not compete with it. The prospects of using online services for reporting a crime by persons with hearing and/or speech impairments are determined. The ways of informing the persons who reported the crime about their rights are shown.
Armenian Apostolic Church Under Bolshevik Ideological and Political Pressure Between 1920 and 1922
Authors: MIRZAKHANYAN Ruben , GRIGORYAN Hayk
Published: June 2021

This article presents the ideological controversies that arose between the Armenian Apostolic church and the bolshevik regime following the invasion of soviet troops into Armenia. From its first days in power bolshevik authorities implemented radical steps against its ideological rival – the armenian church. Following the harsh anti-church political line of Russian bolsheviks, the soviet authorities in Armenia started a massive appropriation of Armenian church properties. The article mentions also the first attempts of the soviet administration to organize state institutions for the preservation and study of national cultural heritage.
An anti-sum-symmetry model and its orthogonal decomposition for ordinal square contingency tables with an application to grip strength test data
Authors: Ando Shuji
Published: June 2021

For the analysis of R × R square contingency tables, we need to estimate an unknown probability distribution with high confidence from obtained observations. For that purpose, we need to perform the analysis using a statistical model that fits the data well and has a simple interpretation. This study proposes two original models that have symmetric and asymmetric structures between the probability with which the sum of row and column variables is t, for t = 2, . . ., R, and the probability with which the sum of row and column variables is 2(R + 1) − t. The study also reveals that it is necessary to satisfy the anti-global symmetry model, in addition to the proposed asymmetry model, in order to satisfy the proposed symmetry model. This decomposition theorem is useful to explain why the proposed symmetry model does not hold. Moreover, we show that the value of the likelihood ratio chi-squared statistic of the proposed symmetry model is equal to the sum of those of the decomposed models. We evaluate the utility of the proposed models by applying them to real-world grip strength data.
Properties of an MLE algorithm for the multivariate linear model with a separable covariance matrix structure
Authors: Szczepańska-Álvarez Anna , Zawieja Bogna , Álvarez Adolfo
Published: June 2021

In this paper we present properties of an algorithm to determine the maximum likelihood estimators of the covariance matrix when two processes jointly affect the observations. Additionally, one process is partially modeled by a compound symmetry structure. We perform a simulation study of the properties of an iteratively determined estimator of the covariance matrix.
Innovativeness of Senior Consumers’ Attitudes – An Attempt to Conduct Segmentation
Authors: Olejniczak Tomasz
Published: June 2021

Research background: Ageing societies is a global phenomenon. In the media and the press, there strongly exists a stereotype of elderly people being poorly adjusted to social change, lonely, poor and not open to market novelties. However, an in-depth description of the senior consumer market segment shows their high degree of variety and differentiation in their approach to purchasing product innovations.

Purpose: The aim of the article is to present a model of segmentation of older people according to the criterion of their attitudes towards innovation on the FMCG market.

Research methodology: The source of information for building the typology was personal interviews conducted in 2018 with people aged over 60 in Greater Poland (the Wielkopolska region). The selection of respondents (the sample consisted of 1,451 people) was carried out using the quota selection method. The K-means clustering algorithm was applied to classify the respondents into clusters.

Results: The research procedure allowed for the identification of different segments of senior consumers: reluctant conservatives, knowledgeable traditionalists, aspiring withdrawn/passive, unaware practical and rational innovators.

Novelty: The results of the analysis of the segmentation of senior consumers confirm that people actively interested in product innovations on the FMCG market constitute a relatively small part of the elderly population (18.0%) and that there is a clear relationship between the attitude towards innovation and the characteristics of consumers in terms of economic, demographic and social variables.
Customer Orientation and Innovation – The Perspective of Top-Level Management
Authors: Widelska Urszula , Krot Katarzyna
Published: June 2021

Research background: Scientific exploration of customer orientation also confirms the existence of connections which occur between the focus of an enterprise on the needs of its customers and the level of its innovativeness. For it is the customer and his/her needs that determine a company’s primary directions of development and, in the end, the customer decides whether to make purchases and accept the company’s offer

Purpose: The goal of the present study is the systemization of knowledge within the scope of customer orientation and dependencies that exist between innovativeness and customer orientation.

Research methodology: Inferences have been supported by the results of a CAWI quantitative survey conducted among 204 business leaders (top managers) from the Podlasie Voivodeship in Poland.

Results: The study results confirm that customer orientation within a company can vary in form and differ in character as well as indicate that innovation can determine the level of customer orientation within an enterprise.

Novelty: The study of the dependence between customer orientation and innovativeness is a challenge for management sciences and is subject to some limitations since both innovativeness as well as customer orientation are structures which are very complex and ambiguous. Innovation becomes a factor unifying a company with a customer because it guarantees the provision of new values and is the answer to the dynamic character of those changes.
The Application of Continuous Quality Improvement Methods at Universities in the Opinion of Students and Lecturers of the University of Lodz
Authors: Zalewska Elżbieta
Published: June 2021

Research background: Total Quality Management – TQM consists in managing an organization in which the continuous striving for quality based on the Deming Cycle is an important assumption. Even though the ‘product’, in reference to higher education, is not the same as in reference to industry, higher education can be improved in terms of quality and the manner of conducting classes, and administrative work by applying the TQM methods.

Purpose: The main purpose of the research conducted at the University of Lodz was to identify and compare the determinants affecting the opinion of the students and lecturers on the assessment of the possibilities and effectiveness of introduction of the CQI methods in the Polish higher education.

Research methodology: Multivariate statistical methods – cluster analysis were used for the analysis and cross tabulations.

Results: Students and lecturers of the University of Lodz positively evaluated the CQI methods. The research shows most of the assumptions of the CQI concept can be adapted to the conditions of work at Polish universities; 68.92% of respondents stated that the CQI methods may be perceived as a concept of improvement of the quality of a university institution; 89.86% of respondents believe that the CQI methods are appropriate on the concept of the improvement of the quality of given classes/lectures.

Novelty: The value of this paper is a contribution to the debate on needs and improving the quality of education at Polish universities.
Spatial resolution of unmanned aerial vehicles acquired imagery as a result of different processing conditions
Authors: Kubišta Jaroslav , Surový Peter
Published: June 2021

Increasing availability of Unmanned aerial vehicles (UAV) and different software for processing of UAV imagery data brings new possibilities for on-demand monitoring of environment, making it accessible to broader spectra of professionals with variable expertise in image processing and analysis. This brings also new questions related to imagery quality standards. One of important characteristics of imagery is its spatial resolution as it directly impacts the results of object recognition and further imagery processing. This study aims at identifying relationship between spatial resolution of UAV acquired imagery and variables of imagery acquiring conditions, especially UAV flight height, flight speed and lighting conditions. All of these characteristics has been proved as significantly influencing spatial resolution quality and all subsequent data based on this imagery. Higher flight height as well as flight speed brings lower spatial resolution, whereas better lighting conditions lead to better spatial resolution of imagery. In this article we conducted a study testing various heights, flight speeds and light conditions and tested the impact of these parameters on Ground Resolved Distance (GRD). We proved that from among the variables, height is the most significant factor, second position is speed and finally the light condition. All of these factors could be relevant for instance in implementation of UAV in forestry sector, where imagery data must be often collected in diverse terrain conditions and/or complex stand (especially vertical) structure, as well as different weather conditions.
Reproduction and Accompanying Fauna of Red Mason Bee Osmia rufa L. (syn. Osmia bicornis L.) in Areas with Different Levels of Urbanization
Authors: Zajdel Barbara , Borański Mikołaj , Kucharska Kornelia , Teper Dariusz
Published: June 2021

An increasing number of studies show that urbanized areas are habitats of high biological value and ecological significance. Most bee species live in areas altered by man, either in cities - fragmented urban habitats - or in large rural monocultures. Our research is based on three-year observations of population development of the solitary bee Osmia rufa L. in three habitat types: city, suburbs and villages. We compared reproductive parameters and diversity of accompanying nest fauna. Population growth rate was high in all habitats, exceeding five times the number of cocoons placed in the previous year. We found no significant differences in the number of cocoons and brood mortality between areas with different urbanization levels. In nests located in suburbs, parasites and cleptoparasites occupied almost three times more nest chambers than in other habitats. Changes in the habitat structure had a significant impact on the diversity and abundance of accompanying fauna. Our study shows that red mason bees are flexible and easily adapt to new conditions, despite changes caused by urbanization and agriculture.