bluuebunny/crossref_metadata_2025 huggingface dataset:
On assigning service life for technical systems under inflation
Authors: Smolyak Sergey
Published: June 2022

A technical system is used by an enterprise that is a typical market participant to perform specific work. During operation, the operating characteristics of the system deteriorate. In case of a possible failure of the system, it is decommissioned and this causes losses for the enterprise. It turns out that it is beneficial to assign a certain service life to the system after which (if no failure has occurred) it is subject to decommissioning. We are solving the problem of optimizing this assigned service life. Usually, when solving it, inflation is not taken into account, and the optimality criteria are the average costs per unit of time and other indicators that do not fully reflect the commercial interests of the enterprise owning the system. Using the principles and methods of valuation, we build a mathematical model and propose formulas that allow us, taking into account inflation, to find the optimal assigned service life of the system and at the same time estimate the market value of the work performed by the system and calculate the change in the market value of the system with age. Moreover, in this problem, the optimality criterion is the ratio of the expected discounted costs to the expected discounted volume of work performed by the system. We show that such a criterion maximizes the market value of the enterprise owning the system. We give examples of using the constructed model. The results obtained can be used both for solving other optimization problems of the reliability theory and for practical valuation of some types of machinery and equipment.
Development and Evaluation of Ensemble Learning Models for Detection of DDOS Attacks in IoT
Authors: YILMAZ Yıldıran , BUYRUKOĞLU Selim
Published: June 2022

Internet of Things that process tremendous confidential data have difficulty performing traditional security algorithms, thus their security is at risk. The security tasks to be added to these devices should be able to operate without disturbing the smooth operation of the system so that the availability of the system will not be impaired. While various attack detection systems can detect attacks with high accuracy rates, it is often impos-sible to integrate them into Internet of Things devices. Therefore, in this work, the new Distributed Denial-of-Service (DDoS) detection models using feature selection and learn-ing algorithms jointly are proposed to detect DDoS attacks, which are the most common type encountered by Internet of Things networks. Additionally, this study evaluates the memory consumption of single-based, bagging, and boosting algorithms on the client-side which has scarce resources. Not only the evaluation of memory consumption but also development of ensemble learning models refer to the novel part of this study. The data set consisting of 79 features in total created for the detection of DDoS attacks was minimized by selecting the two most significant features. Evaluation results confirm that the DDoS attack can be detected with high accuracy and less memory usage by the base models com-pared to complex learning methods such as bagging and boosting models. As a result, the findings demonstrate the feasibility of the base models, for the Internet of Things DDoS detection task, due to their application performance.
The Structure-Activity Relatıonships of Familiar Antiepileptic Drugs and Na+ Channels
Authors: ÇAKMAK Esra Nur , GÜR Mahmut , KIRAN Bayram
Published: June 2022

The aim of this study is to examine the effects of drug active compounds, which are widely used in the treatment of epilepsy, on voltage-gated Na+ channels are important channels that advance the action potential in the excitation direction by molecular docking method. These molecules have been selected considering the physiopathological effect mechanisms of epilepsy disease. When the action potential is stimulated, Na+ channels allow sodium ion entry into the cell and cause epilepsy seizures. For this reason, PDB ID: 4PA6 receptor, which acts as an antagonist according to its activity on the canal in the formation of epileptic seizures, was chosen for molecular docking study. As a result of molecular docking studies; Phenytoin gave the best binding affinity for 4PA6 with a value of -7.7 kcal/mol. Other results in descending order (as kcal/mol); Mesuximide (-7.5), Remasemide (-7.3), Tiagabine (-7.1), Ethotoin and Mephenytoin (-7.0), Primidon (-6.9), Topiramate (-6.6), Oxcarbazepine and Lamotrigin (-6.3), Felbamat (-6.0), Lokosamidine (-5.9), Zonisamide (-5.8), Levetiresetam and Gabapentin (-5.7), Ethosuximide (-5.6), Trimethadion (-5.1), Valproic Acid (-5.0), Vigabatrin (-4.0), determined as.
A random maintenance last model with preventive maintenance
for the product under a random warranty
Authors: Shang Lijun , Zou Anquan , Qiu Qingan , Du Yongjun
Published: June 2022

Although renewing pro-rate replacement warranty (RPRW) can help producers obtain some
compensation from users, there seldom exists a two-dimensional random RPRW with a
refund (2D-RRPRW with R) where a refund can guarantee the fairness of users. In addition,
although random periodic replacement last (RPRL) can extend the service span after the
expiry of the warranty, RPRL considering preventive maintenance (PM) has been seldom
modeled to further lengthen the service span after the expiry of the warranty. In view of
these, a 2D-RRPRW with R is devised to guarantee the fairness of users by integrating the
limited job cycles and a refund into RPRW. Under the case where 2D-RRPRW with R warrants products with job cycles, a RPRL with PM is modeled to further lengthen the service
span after the expiry of the warranty and reduce the failure frequency. It shows that to shorten the warranty period can makes the warranty cost of 2D-RRPRW with R to be less than
the warranty cost of classic RPRW; and the performance of RPRL with PM outperforms the
performance of classic RPRL.
COVID-19 Vaccine Hesitancy: Mobile Education Initiatives to Improve Vaccination Uptake among Healthcare Workers
Authors:   Clinical Research Centre, Hospital Tuanku Fauziah, Jalan Tun Abdul Razak, 01000 Kangar, Perlis, Malaysia., Khalid Karniza
Published: June 2022

Vaccine hesitancy is a global threat to public health contributed by misinformation and lay beliefs about diseases and health. Our study aimed to assess preparedness and intent to receive COVID-19 vaccine among healthcare workers in a single institution in northwest Malaysia and assess the feasibility and efficacy of our mobile education programme to overcome vaccine hesitancy among healthcare workers. Our initial survey among 1,616 respondents found that 25.3% of healthcare workers either refused or were hesitant towards COVID-19 vaccination; 238 respondents (58.2%) of which with no absolute clinical contraindication. Our multifaceted mobile education programme involved: (i) series of continuous medical education (CMEs) to 72 elected liaison officers, (ii) small scale briefing session to individual unit and/or department upon request, and (iii) a one-to-one counselling session upon request. The programme took the course of over four weeks prior to the actual vaccination drive. Re-assessment of intent to receive COVID-19 vaccine found a significant reduction of healthcare workers refusing COVID-19 vaccination without absolute contraindication (25.3% vs. 2.8%). The most common reasons cited among those who were still hesitant were due to pregnancy (non-first trimester) and planning to conceive in the near future. Our study demonstrated the efficacy of physical interaction and teaching session to allow rapid communication and gives better understanding, particularly when dealing with myths, misinformation and misconception related to COVID-19 vaccine.
New Anomaly Network Intrusion Detection System in Cloud Environment Based on Optimized Back Propagation Neural Network Using Improved Genetic Algorithm
Authors: Chiba Zouhair
Published: June 2022

Cloud computing is distributed architecture, providing computing facilities and storage resource as a service over an open environment (Internet), this lead to different matters related to the security and privacy in cloud computing. Thus, defending network accessible Cloud resources and services from various threats and attacks is of great concern. To address this issue, it is essential to create an efficient and effective Network Intrusion System (NIDS) to detect both outsider and insider intruders with high detection precision in the cloud environment. NIDS has become popular as an important component of the network security infrastructure, which detects malicious activities by monitoring network traffic. In this work, we propose to optimize a very popular soft computing tool widely used for intrusion detection namely, Back Propagation Neural Network (BPNN) using an Improved Genetic Algorithm (IGA). Genetic Algorithm (GA) is improved through optimization strategies, namely Parallel Processing and Fitness Value Hashing, which reduce execution time, convergence time and save processing power. Since,  Learning rate and Momentum term are among the most relevant parameters that impact the performance of BPNN classifier, we have employed IGA to find the optimal or near-optimal values of these two parameters which ensure high detection rate, high accuracy and low false alarm rate. The CloudSim simulator 4.0 and DARPA’s KDD cup datasets 1999 are used for simulation. From the detailed performance analysis, it is clear that the proposed system called “ANIDS BPNN-IGA” (Anomaly NIDS based on BPNN and IGA) outperforms several state-of-art methods and it is more suitable for network anomaly detection.
Workload Cluster Balance Algorithm to Improve Wireless Sensor Network Performance
Authors: Jedidi Ahmed
Published: June 2022

Wireless sensor Networks (WSNs) became in one of the important technologies in our days in which it is applied in many applications and domains. The low cost technology of the WSNs is the first obstacle to improve performance in these applications. However, the usual methods of routing algorithm cannot be applied in WSNs. Consequently, an adaptive routing algorithm is critical issue in the current deployment of WSN applications. The main contribution of this paper is to develop a new routing protocol that address performance challenges in WSNs this will consequent extend the network lifetime of WSN. Moreover, this proposed algorithm uses a new cluster system to define a route from source node to sink node in which the balance load cluster routing algorithm consists to balance the workload between the different nodes to keep the lifetime for the whole network. As a result, the proposed algorithm improve the network lifetime by 22% compare to existing algorithms and the average of the energy consumption is decreased by 18%.
Karma Lif Takviyeli KYB Karışımlarının İşlenebilirlik ve Mühendislik Özelliklerinin Araştırılması
Authors: TÜRK Kazım , KATLAV Metin , TURGUT Paki
Published: June 2022

Bu çalışmada, benzer işlenebilirliğe sahip farklı boyut (makro ve mikro) ve narinlikteki çelik lif takviyeli kendiliğinden yerleşen beton (KYB) karışımların mühendislik ve işlenebilirlik özellikleri araştırılmıştır. Bu amaçla, lifsiz, sadece makro lif ve karma lif içeren KYB olmak üzere toplamda üç adet karışım tasarlanmıştır. Lifli KYB karışımları, EFNARC (2002) komitesi tarafından önerilen kriterlere göre mümkün olan benzer işlenebilirlik esas alınarak elde edilmiştir. Bu sebeple, çökme-yayılma, t500 ve J-halkası işlenebilirlik testleri yapılmıştır. Elde edilen lifli KYB karışımlarından 3, 28 ve 90 günlük basınç, yarmada çekme ve eğilmede çekme dayanımlarının belirlenmesi için numuneler hazırlanmış ve standartlara uygun şekilde test edilmiştir. Sonuç olarak, karışıma hem tekli hem de karma lif ilave edilmesi, karışımların işlenebilirlik özelliklerini olumsuz etkilemiştir. Bunun yanında, KYB karışımlarına narinliği 87 olan düz mikro çelik liflerin ilave edilmesinin basınç ve yarmada çekme dayanımlarında, narinliği 65 olan kancalı uçlu makro çelik liflerin ilave edilmesinin ise eğilmede çekme dayanımı değerlerinde olumlu bir etkiye sahip olduğu bulunmuştur.
Design of a 3D Printed Open Source Humanoid Robot
Authors: PARALI Levent , SARI Ali , ESEN Mehmet
Published: June 2022

Nowadays, humanoid robots with great capabilities used in a variety of purposes to serve humans have become an integral part of our lives. In this study, we have developed a low-cost humanoid robot that can be fabricated with an open-source 3D printer. Firstly, the 3D-CAD model of the humanoid robot was created using source codes of the “InMoov” project which is originated by Gael Langevin who works as a designer on his project since 2012. The humanoid robot involves approximately 685 parts built from the PLA (Poly-Lactic Acid) raw material. After that, a new electronics system based on the embedded controllers which have been controlled with the python programming language has been designed. This robotic platform controlled with the help of voice commands has the capability to communicate with people. Furthermore, a skilled prosthetic hand controlled according to the commands from a smart glove, can grasp and holds objects, have been specially developed in this study. When comparing to the existing commercial humanoid robots, this humanoid robot developed as specific has a substructure which is not only low cost but also open to new improvements as well.
Hadis Literatüründe Yüz Hadisler
Authors: HALİLOĞLU Mevlüt
Published: June 2022

Hz. Peygamber’in (sas) hadislerinin yazılı metinleri ve bu metinler üzerine yapılan çalışmalar, hadis literatürünü oluşturmaktadır. Hadisler, hıfz, kitâbet ve tedvin safhalarından sonra tasnif döneminde kitaplardaki yerini almış, böylece temel hadis kitapları oluşmuştur. Hicrî beşinci asırdan beri hadis alimlerinin temel hadis kitapları üzerinde yaptıkları çalışmalarla, hadis tarihi boyunca binlerce hadis kitabı tasnif ve te’lif edilmiştir. Yüz hadis kitapları da bunlar arasındadır. Arapça olarak on beş adet yüz hadis kitabı bulunabilmiş olup bunlardan dördü incelenmiştir. Türkçe’ de ise ulaşılabilen biri mensur, diğerleri manzum yedi adet yüz hadis kitabı tetkik edilmiştir. İncelenen eserlerdeki hadislerin çoğunlukla ahlâkî konularla ilgilidir. Yüz hadis kitaplarının Türk-İslam kültürünün ürünü olduğu intibaını vermektedir.
The Effect of Chitosan-Gelfoam Cacao Pod Husk on Wound Epithelial Thickness in the Post-Extraction Tooth with Anticoagulant Therapy
Authors: Swastirani Astika , Marsudi Fiorina Divasinta Mirelia
Published: June 2022

Tooth extraction is removing a tooth from its socket when it cannot be restored. Tooth extraction performed in patients on anticoagulant therapy can increase the risk of excessive bleeding. Therefore, a local hemostatic agent is needed to accelerate the hemostasis process and reduce the risk of tooth extraction complications in anticoagulant users. This study aims to determine the effect of chitosan-gelfoam extract of cacao pod husk to increase epithelial thickness in the post-extraction socket of male Wistar rats with anticoagulant therapy. This research used quantitative data collection techniques on 24 male Wistar rats who were given anticoagulant therapy. It was divided into eight groups: negative control group H+3, negative control group H+7, positive control with oral tranexamic acid therapy H+3, positive control with oral tranexamic acid therapy H+7, treatment 1 with 1 ml chitosan-gelfoam cacao pod husk extract therapy H+3, treatment 1 with 1 ml chitosan-gelfoam cacao pod husk H+7, treatment 2 with 10 ml chitosan-gelfoam cacao pod husk H+3, and treatment 2 with 10 ml chitosan-gelfoam cacao pod husk H+7. The test animals were decapitated on the 3rd and 7th day. The histology preparations, observations, and statistical tests were then carried out. The statistical tests showed that chitosan gelfoam extract of cacao pod husk with doses of 1.6% and 15% extract of cacao pod husk was able to replace the effectiveness of tranexamic acid. The 15% dose had better significance than the 1.6% dose. This research is expected to contribute to the farmers’ welfare and the cacao industry by converting cacao pod waste into helpful medicine.
3D Orientation Estimation Using Inertial Sensors
Authors: Bai Lu
Published: June 2022

Recently, inertial sensors have been widely used in the measurement of 3D orientations because of their small size and relative low cost. One of the useful applications in the area of Neurorehabilitation is to assess the upper limb motion for patients who are under neurorehabilitation. In this paper, the computation of the 3D orientation is discussed utilising the outputs from accelerometers, gyroscopes and magnetometers. Different 3D orientation representations are discussed to give recommendations for different use scenarios. Based on the results form the 3D orientation, 2D and 3D position tracking techniques are also calculated by considering the joint links and kinematics constraints from the upper limb segments. The results showed that the performance using complementary filter can make good estimation of the orientation.
Taḥlīl Ahliyyati Muḥtawiyāti Kitābi Qawā’idī Fī Al-Jawāhir Al-Maḥmūd Min An-Naḥwi Wa Aṣ-Ṣarfi Lisy-Syaikh Baḥr Al Munīr Al-Ḥamīm Trenggalek
Authors: Sholihah Niswatush , Arifin Zainal
Published: June 2022

Penelitian ini bertujuan untuk mengetahui kelayakan isi Kitāb Qawā’idī karya Syekh Bahr Al-Munir Al-Hamim Trenggalek dengan standar buku teks yang baik menurut tujuan, kualitas, kaidah penulisan dan bagian-bagiannya. Penelitian ini merupakan penelitian deskriptif kualitatif. Pengumpulan data melalui metode observasi dan dokumentasi. Analisis data dilakukan dengan identifikasi data, penyajian data, dan penarikan kesimpulan. Adapun hasil penelitiannya yaitu buku ini sesuai dengan standar buku teks yang baik sesuai dengan tujuan, kualitas, kaidah penulisan dan bagian-bagiannya, yaitu memiliki sudut pandang dan konsep yang jelas, sesuai dengan kurikulum 2013 dan kurikulum terpadu, mempunyai media pendidikan yang baik, mempunyai kesesuaian dengan standar keterkaitan dengan materi lain, menarik minat siswa, dan memiliki nilai-nilai kebaikan yang membentuk akhlak yang baik bagi siswa, yaitu pengembangan aktivitas siswa dalam menganalisis semua komponen, pengembangan aktivitas siswa dalam berbicara, yaitu dengan bernyanyi, pengembangan siswa dalam berpikir, dan pengembangan aktivitas siswa dalam berbicara, serta pengembangan toleransi siswa. Namun, berdasarkan pedoman penulisan buku teks yang baik, kitab ini tidak sesuai dengan etos kerja praktek serta tidak memiliki daftar gambar, daftar tabel, dan halaman penutup di dalamnya.
Study of various laboratory parameters in COVID-19 patients at a tertiary care center
Authors: Kumar Harendra , Kumar Lalit , Kaushik Nupur , Singh Rajdeep , Gautum Ashish
Published: June 2022

In China, Wuhan City became the epicentre of unexplained cases of pneumonia in December 2019 and was temporarily labelled as, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). World Health Organization renamed it to coronavirus disease 2019 (COVID-19) in February 2020. In COVID-19 patients hematological profile showed increased total leukocyte count (TLC) and neutrophilic count, while decrease in other hematological parameters. The mild increase in TLC was found in severe disease patients; however significant increase was associated with clinical worsening and poor outcome. Significant elevation of various biochemical and inflammatory markers was noticed among COVID-19 patients

We conducted a retrospective study on RT-PCR confirmed 239 COVID-19 patients who were hospitalized in various COVID-19 facilities from Sept 2020 to Dec 2020. The laboratory data is used in de-identified form and doesn’t reveal identity of any subjects.

A total of 239 cases were examined, out of which 176(73.7%) were male and 63(26.3%) were female (M:F ratio= 2.79:1). We found that 104 cases had Hb level ≥ 12gm/dl. We found that maximum patients (175) had TLC level >11000/cumm, 187 patients had ANC level > 7000/cumm. We found that 160 cases had serum urea of >43mg/dl, 134 case with serum creatinine of >1.4gm/dl.134 cases had ALT level of >40IU/L and 143 cases had AST levels of >42IU/L In this study out of 239 cases 126 cases were found to have increased level of all inflammatory markers levels.

We found a significant association of various inflammatory markers with haematological and biochemical parameters in COVID-19 patients.
Clinical profile of extra pulmonary tuberculosis: A retrospective south Indian study
Authors: Palani Vinodh Kumar , Sahukar Shruthi Basavaradhya , Ranganathan Raghini , Kumpthala Satyavani
Published: June 2022

: Tuberculosis (TB) is one of the most important global health problems. The prevalence of TB is high among the developing world. India has the highest TB burden, accounting for 1.9 million cases of the 9.1 million cases of globally. Although tuberculosis is primarily the disease affecting the lungs, Called Pulmonary TB (PTB), it may also affect other sites such as lymph nodes, central nervous system, bones, and gastrointestinal tract which is known as Extra pulmonary tuberculosis (EPTB). Extra-pulmonary TB patient reporting has been increased from 17% to 21% over period of 10 years which demands the evaluation of clinical profiles of EPTB in order to diagnose and implement the precise treatment plan.

: To Determine the clinical profile of extra pulmonary tuberculosis (EPTB) patients in South Indian population.

: Three years’ retrospective data of TB patients from 2015 – 2017 registered in 4 TB units of central Chennai was collected. The Study included the confirmed cases of EPTB without co-infections. Parameters such as Socio-demographic variables, clinical features and treatment outcome was collected. Age and gender wise comparisons was done for all the parameters using descriptive statistics.

Lymphnode TB was the most common type of EPTB and significant association between age, gender and site of EPTB was found in the study necessitating well planned strategies, program-specified protocols for the diagnosis and treatment of extra pulmonary tuberculosis cases.
A challenging case of a tanycytic ependymoma – A case report
Authors: BD Impana , S Seethalakshmi , Jeris W.Lydia , R Raghavendran
Published: June 2022

Intramedullary spinal cord neoplasms are among one of the rare tumors and account for 4% to 10% of all the central nervous system tumors. Spinal cord ependymomas are the most common type of tumors in adults, and astrocytomas of the cord are most common in children. Among the ependymomas, Tanycytic type is a rare one that usually arises in the intramedullary part of the spine. The histology is unique which is emphasized by the absence of ependymal pattern of cells but has close resemblance to schwannoma and astrocytoma which poses a diagnostic challenge. Hereby we present a case of a young male diagnosed as tanycytic ependymoma but was initially thought to be a glioma clinically. The histology showed spindle cells with oval and elongated nuclei in fascicles in a fibrillary background suggesting a preliminary diagnosis of glioma / schwannoma. However with the help of Immunohistochemical staining, a strong immunoreactivity for glial fibrillary acidic protein (GFAP) with S-100 positivity, confirmed that the tumor was a tanycytic ependymoma. This case underlines the importance of accurate diagnosis of CNS tumors with the help of age, location, detailed histopathological examination and immunohistochemistry to differentiate from other neoplasms as treatment differs for different tumors.
Um Ensaio Sobre Ciência e Arte a Partir da Obra de Cecília Meireles
Authors: Amorim Monteiro Julia , Silveira Camila
Published: June 2022

Cecília Meireles, renomada escritora brasileira, teceu sua trajetória escrevendo sobre Folclore, Educação e Educação Infantil em colunas de jornais, poemas e crônicas. Essas faces da vida da autora foram e são amplamente estudadas. Uma possibilidade de estudo que encontramos nestas obras, foram escritos de Cecília que se remetem à Ciência, especificamente no livro O Estudante Empírico, publicado em 1974. Sendo assim, este ensaio tem como objetivo traçar uma articulação entre Ciência e Arte a partir do poema Mapa da Anatomia: O Olho, presente no livro citado. As aproximações entre Ciência e Arte feitas a partir do poema convergem para uma compreensão de que ambas produções humanas são históricas e sociais, se configuram como linguagem e tomam a realidade como ponto de partida. Além disso, apesar de suas especificidades, Ciência e Arte podem empregar criatividade, sensibilidade e emoções, bem como a racionalidade e a lógica. Por fim, podemos considerar a potência de ambas as produções na formação de sujeitos que consigam ter uma visão de mundo global, neste caso, tendo a Ciência e a Arte como fios condutores possíveis para essa formação.
Allah-La-Ô: Caminhos para a Conscientização sobre o Consumo de Álcool por meio das Marchinhas Carnavalescas da Década de 1950
Authors: Ribeiro da Silva Frederico Augusto
Published: June 2022

Os festejos carnavalescos podem ser entendidos como retratos populares dos mais diversos momentos já vividos pelo país, criando um conjunto de quadros históricos em que estão, por exemplo, as marchinhas cantadas em Carnavais da década de 1950. Logo, considerando a importância da realização de pesquisas voltadas para a arte nacional e da produção de estudos interdisciplinares relacionados à experiência com bebidas (tema que está intimamente ligado à saúde pública), o artigo tem como objetivo investigar possíveis caminhos para a sensibilização acerca da ingestão excessiva de álcool por meio de cinco marchinhas carnavalescas cantadas na década de 50 do século XX. Para tanto, foi escolhida uma metodologia qualitativa e procedimentos típicos da análise de discurso. Pelos caminhos percorridos, acredita-se que as escolas, assim como ambientes de educação não formal, podem ser espaços onde tais canções têm o potencial de se tornarem ferramentas lúdicas para a compreensão das múltiplas dimensões que envolvem o consumo alcoólico.
Influence of conditioned media from glial cell cultures on contractility of uterine in rats of different ages
Authors: Nesteruk H.V. , Alabedalkarim N.M. , Komaromi N.A. , Tkachenko N.О. , Protsenko O.S. , Lehach Y.I.
Published: June 2022

Background. The physiological regulation of the uterine contractile activity changes with age, which leads to an increased number of prolonged labor and emergency caesarean sections in women giving birth at the age of 35+. One of the modern approaches to correct the function of the reproductive system is the use of from cell cultures. CM from glial cell culture contains neurotrophic factors that play an important role in maintaining the contractile function of the uterus. Current cell culture technologies include cryopreservation.Objective: to research experimentally the effect of CM obtained from intact and cryopreserved cultures of glial cells on the contractile activity of the uterus in rats of different reproductive ages.Materials and methods. The monolayer cell culture was obtained from the dorsal root ganglia of neonatal piglets and cryopreserved in the presence of cryoprotectant dimethyl sulfoxide. CM from native and cryopreserved cultures were collected for 28 days, after which fractions with a molecular weight of < 30 kDa were obtained from them by ultrafiltration. Rats at the age of 6 and 14 months, which corresponds to reproductive age and late reproductive age (LRA), were intraperitoneally injected with 0.2 ml of media from intact (ICM) or cryopreserved (CCM) cultures for 9 days. On the 30th – 32nd day after the end of the administration of CM animals were slaughtered and the uterine contractile activity was determined by the organ bath method, the relative area of myometrium and density of myocytes by histological method, the average area of labeling with specific antibodies to smooth muscle actin by immunohistochemical method. The statistical significance of differences was assessed by the Mann–Whitney test.Results. It was found that spontaneous, OT-, and KCl-induced tension of isometric contraction of the uterus in intact LRA rats decreased by 19, 20, and 14%, respectively, compared with intact reproductive aged animals. After the introduction of ICM and CCM in LRA animals, normalization of isometric contraction parameters was observed. This effect was realized against the background of an increase in the area of the myometrium, the density of myocytes, and actin expression.Conclusions. Intra-abdominal administration of CM from glial cell culture increases the uterine contractile activity in LRA rats. This effect is realized by increasing the relative area of the myometrium, the density of myocytes, and the area of expression of smooth muscle actin. The effect of media from intact and cryopreserved cultures on the contractile activity of the uterus was similar, which makes it possible to use low-temperature culture storage technologies to obtain CM without losing its biological effect.
Seyfüddîn el-Âmidî’nin Mu‛tezile’ye Yönelik Eleştirileri
Authors: YAVUZ Abdullah Ömer
Published: June 2022

İslam düşünce geleneğinde mezheplerin tarihsel hafızaları muhatap veya muhalif oldukları ekollerden etkilenmektedir. Eş‛arîliğin tarihsel sürecinde Mu‛tezile ile olan ilişkisi, mezhebi hafıza ve bunun neden olduğu algının tezahürleri üzerinden ilerlemektedir. İmam Eş‛arî’nin kırklı yaşlarında Mu‛tezile’den ayrılmasıyla başlayan süreç, iki mezhebi sürekli karşı karşıya getirmiştir. Bu araştırma, Mısır-Şam bölgesinde Eş‛arîliğin Mu‛tezile’yi algılayış biçimini, Seyfüddîn el-Âmidî üzerinden değerlendirmeyi amaçlamaktadır. İslam Mezhepleri Tarihi araştırmalarında kullanılan şahıslar üzerinde derinleşme prensibini merkeze almaktadır. Çünkü, Âmidî’nin Mısır-Şam Eş‛arîliği çerçevesinde kendine has bir konu-ma sahip olması Mu‛tezile eleştirileri-ni daha da önemli hale getirmekte-dir. Âmidî, incelediği pek çok konu-da Mu‛tezile’nin görüşlerine yer verip çoğu kez eleştirmekte bazen de doğ-ru bulmaktadır. Eleştirilerinde kimi zaman genelleyerek Mu‛tezile olgu-sunu öne çıkarırken bazen de isim isim Mu‛tezilî bilginlere yer vermektedir. Âmidî’nin Mu‛tezile’ye yönelik eleştirilerinin başında bilgi kuramına dair meseleler gelmektedir. Mu‛tezilî akılcılığına karşı felsefi bir akılcılığı öne çıkarmaktadır. Âmidî’nin Mu‛tezile’ye yönelttiği eleştirilerinin ikinci ana sahası kelâmî konular üzerinedir. Bu gerilimin temelinde ise Allah tasavvuru yatmaktadır. Âmidî’nin Mu‛tezile’ye yönelik eleşti-rileri felsefi birikiminden, Eş‛arî kim-liğinden ve özgün ilmi yaklaşımından beslenmektedir.
el-Esmâ ve’l-Ahkâm Görüşleri Bağlamında İbâdiyye-Mu‘tezile Etkileşimi
Authors: YOLDAŞ Mehmet , KUBAT Mehmet
Published: June 2022

Hz. Ali’nin hilafet yıllarında yaşanan fitne olayları, fırkalaşma hareketlerinin başlamasına neden oldu. Bu dönemdeki toplumsal-siyasal olayların sonucu çeşitli konular farklı mahfillerde tartışılıyordu. Tartışılan konulardan “iman-kebire” ilişkisi gündemin en önemli konusuydu. Bu tartışmaların hararetle yapıldığı yerlerin başında Basra gelmekteydi. Basra’da etkin olan gruplar içerisinde İbâdiyye önemli bir konuma sahipti. Aynı şekilde Mu‘tezile’nin de ilim çevrelerinde hatırı sayılır bir ağırlığı bulunmaktaydı. Her iki mezhebin görüşleri incelendiğinde bazı konularda benzer düşüncelerin varlığı söz konusudur. Bir yandan bedevî kökenli İbâdiyye, diğer yandan entelektüel yönü ağır basan mevâlî kökenli Mu‘tezile arasında etkileşimin olacağını düşünmek mümkün görünmemekle beraber eserlerde zikredilen fikri yakınlık örnekleri, bu iki mezhep arasında bir fikri etkileşimin varlığını akla getirmektedir. Makalemizde “el-esmâ ve’l-ahkâm” görüşleri bağlamında her iki mezhep arasında özellikle teşekkül dönemlerini dikkate alarak fikirlerin benzerliğini tespit etmeye ve aralarında var olduğunu düşündüğümüz etkileşimi ortaya koymaya gayret edeceğiz.
The Presentation of Zaydiyya in Sunnī and Shi`ite Maqālāt Tradi-tion: A Comparative Approach to the Maqālāt of Abū l-Ḥasan al-Ashʿarī and Saʿd b. Abdullah al-Qummī
Authors: BAYRAM Aydın
Published: June 2022

Zaydiyya, which is one of the main branches of Shīʿa that has survived until today, is considered to be the closest group to Sunnīsm with its theo-logical and political views. Zayd b. ʿAlī (d. 122/740), the grandson of ʿAlī b. Abī Tālib in the fifth generation, was left alone by the majority of the Shi’ites due to his views on the imāmate in the rebellion he started against the Umay-yads. Those who adopted Zayd b. ʿAlī 's views and followed him experienced some differences on their opinions over time. From a comparative perspective, this study deals with how Zaydiyya and its subsects being examined in some early samples of maqālāt tradition (one of the heresiography types) namely, Maqālāt al-islāmīyīn wa-ihtilāf al-musallīn written by Abū l-Ḥasan ʿAlī ibn İsmāʿīl ibn İsḥāq al-Ashʿarī (d. 324/935-6) and Kitāb al-maqālāt wa’l-firāq written by Saʿd b. Abdillah al-Qummī (d. 307/913-4). The main pur-pose of this study is to make a com-parative analysis by revealing how a branch of Shīʿa is described by two authoritative figures accepted in both Sunnī and Shīʿa as far as the history of Islamic sects concerned. This article has been prepared in accordance with re-search and publication ethical rules.
Ebû’l-Kâsım Abdilvâhid b. Ahmed el-Kirmânî’ye Nispet Edilen 73 Fırka Tasnifli Bir Risâle’nin Tahlil ve Tercümesi
Authors: AHMETOĞLU Şahin , DEMİR Habip
Published: June 2022

İslâm Mezhepleri Tarihi yazıcılığı zengin bir birikime sahiptir. Nitekim yüz yıllardır mezhepler hakkında çok sayıda çalışmanın kaleme alındığını görmekteyiz. Bu çalışmalardan birçoğu tespit edilerek neşri yapılmış, birçoğu ise araştırılmak için kendi sırasını beklemektedir. Çalışmamızda konu edindiğimiz ve muhtemelen müstensih tarafından “Şerhü kavli aleyhisselam:“Setefteriku Ümmetî alâ Selâse ve Seb’îne Fırkaten ve Ta‘dîdiha bi-Esmâihâ” olarak isimlendirilen risâle, Ebû’l-Kâsım Abdilvâhid b. Ahmed el-Kirmânî’ye nispet edilmiş olup 4.-5./10.-11. yüzyıllar içerisinde kaleme alındığı tahmin edilmektedir. Risâlenin içeriğinden müellifin Ashâbu’l-Hadîs çizgisine mensup olduğu anlaşılmaktadır. Çalışmamızda, Kirmânî’ye nispet edilen ve “73 fırka” hadisi eksenli olarak hazırlanan bu risâleyi farklı yönlerden inceleyerek değerlendirmeler yapmayı hedefledik. Bunun için risâlenin ilk önce İslâm Mezhepleri Tarihi bilimi içerisindeki yerini ele aldık. Arkasından risâlenin genel özellikleri hakkında bilgiler verdik. Daha sonra risâlenin tasnif sistemini ele alarak kendisinden önceki ve sonraki dönem eserleri ile karşılaştırmalı şekilde değerlendirmelerde bulunduk. Buna ilaveten risâlenin metodu ve içeriğinden bahsederek tercümesini ve yazma nüshalarını da metnin sonuna ilave ettik.
Index of Attitude towards Scientific Research in Peruvian Psychology Students
Authors: Hernandez Ronald M , Montes-Valer Esther , Mamani-Benito Oscar , Ortega-Pauta Beatriz I , Saavedra-Lopez Miguel A , Calle-Ramirez Xiomara M
Published: June 2022

The attitude towards scientific research of university students is a determinant index of the education quality in an institution, and it is fundamental to consolidate the profession as a science. The aim of this study was to describe the attitudes towards scientific research of the Peruvian students of the professional program of psychology. The research approach was quantitative, non-experimental design of basic and field type. The sample consisted of 546 undergraduate students of the professional program of psychology. A sociodemographic form and the Index of Attitude towards Research were used to collect information. The results show that psychology students have an unfavorable attitude towards research. Likewise, they have a low opinion about their self-assessment of research skills, the quality of human resources in teaching research and the promotion of research by the university where they study. In conclusion, it is essential to promote strategies to improve students' attitudes towards research, reinforcing the quality of research courses and selecting teachers with knowledge of research and potential for scientific production.
RESEARCH OF COGNITIVE ACTIVITY OF PRESCHOOL CHILDREN WITH SPEECH DISORDERS
Authors: Sokolova H. B.
Published: June 2022

Modern requirements for the development of personality in the earlystages of ontogenesis provide for its diverse enrichment: spiritual, moral,intellectual, social and communicative, and others. A significant place inthis process is occupied by the child’s speech development, which in preparationfor the reform of preschool education is formed into a holisticeffective system that should successfully solve the problem of combiningspeech development and stimulating cognitive activity in different socialand psychological-pedagogical situations.But, despite the sufficient number of studies of the speech sphere ofpersonality in the Ukrainian psychological science, the issues of studyingthe cognitive activity of children with speech disorders remain out of theattention of scientists. This direction is especially important because anumber of scientists emphasize that the development of speech is closelylinked with the formation of the most important mental functions: sensation,perception, memory, attention, imagination, and through the stimulationof speech develops thinking and such important competencies asthe ability to awareness and expression of the perceived, etc.Thus, the importance of the problem of development of cognitive activityof children with speech disorders at different stages of preschoolage is relevant and practically significant.The purpose of the article: to identify the level of development ofcognitive activity of children with speech disorders and different stagesof preschool age.The objectives of the study at the ascertaining stage were: to investigatethe levels of development of cognitive activity of children of junior,middle and senior preschool age with speech disorders; identify levels ofcognitive activity of children with speech disorders.Object of research: the personality of a preschool child with speechdisorders. Subject of research: features of cognitive activity of preschoolchildren with speech disorders. The results of empirical research haveshown that preschool children with speech disorders have a low level ofcognitive activity (for all tasks assigned to children).Based on the results, we assume that special attention on the backgroundof the correction of speech disorders should be paid to the formationof the emotional component of cognitive activity of children; to formperception; expand the range of external and internal cognitive actions.
THE ILLUSION OF CONTROL AS A CATEGORY OF THE ILLUSION OF THINKING
Authors: Shovkova O. D.
Published: June 2022

People often make mistakes evaluating their personal control over certain situations. It is the result of a normal functioning of cognitive system. The illusion of control is a cognitive bias. It is our tendency to believe that, or act as if, we can skillfully influence and control outcomes of chance events. The illusion of control occurs when individuals overestimate their personal influence over an outcome. The article provides a theoretical analysis of the concept of «the illusion of control» in cognitive psychology. Langer (1975) originally proposed that the illusion of control occurs because people confuse skills and chance situations. Langer found that people’s confidence in their chances of winning was influenced by many different factors—none of which actually had any effect on their chances of winning. Thompson et al. (1998) have presented a more comprehensive explanation of the illusion of control based on a control heuristic that can account for more of the findings. According to the control heuristic explanation, people use both connection and intention to judge their control. Because both can be present even when control is not, personal control is often overestimated. The illusion of control is affected by skill-related factors, success or failure emphasis, need or desire for the outcome, mood, intrusion of reality, power, and regulatory focus. The illusion of control consists of overestimating the influence that our behavior exerts over uncontrollable outcomes. The challenge for scientists is to research how individuals manage their use of illusory control across a variety of circumstances to find optimal effects.
PSYCHOLOGICAL FEATURES OF EXPRESSED EMOTION IN INDIVIDUALS WITH MEDICAL CONDITIONS
Authors: Pastryk T. V.
Published: June 2022

The article is an attempt to discuss psychological featuresof individuals with bowel diseases, namely irritable bowel syndrome, ulcerative colitis, Crohn’s disease as well as diabetes, bronchial asthma inrelation to expressed emotion. Expressed emotion is manifested throughrelatives’ attitude and behavior towards those individuals. Such behaviorcan include hostile attitude, critical comments, emotional overinvolvement.This expressed emotion on the part of family relatives typically cancause the worsening of the sick individual psychological state. A specialfocus in this study is on the individuals with bowel syndromes and theirpsychological states. The research goal is to find out the specifics of theexpressed emotion impact on the quality of life of individuals with medicaldiagnoses. Theoretical literature overview, deduction, induction wereamong the main research tools. Results of the study have shown that thepsychological states of sick individuals clearly correlate with expressedemotion on the part of their spouses/ parents or relatives who typicallydemonstrate critical comments, overinvolvement. Future studies of boweldiseases and expressed emotion would benefit from concentrating on aclearly defined and relatively homogeneous group of individuals.
BULLING CHILDREN WITH AUTISM SPECTRUM DISORDER
Authors: Dushka A. L.
Published: June 2022

The article is devoted to a review of existing research on bullying of children and adolescents with autism spectrum disorder (ASD). Particular attention is paid to the prevalence of this phenomenon, risk factors, forms and consequences of bullying, as well as the possibility of intervention. It is necessary to expand the available knowledge base on this problem, as well as propose practical, sound approaches to its solution. Community awareness of bullying and understanding of the importance of the problem have increased somewhat in recent years. However, RAS students are still extremely vulnerable to bullying, so parents, teachers, classmates and other members of society should be sensitive to the needs of such students. There is no one-size-fits-all way to learn about bullying right away. Children’s reaction to bullying depends on its severity, on its nature. Among those most at risk are children with ASD, Asperger’s syndromeand those with difficulty understanding social conventions, and teens who attend regular schools or have several behavioral problems. The basis of any intervention should be an understanding that children with ASD are at high risk, and adjusting the chosen technique according to their specific needs. In light of the above, there is an urgent need for further research to evaluate the effectiveness of comprehensive, multilevel intervention strategies aimed at preventing and reducing bullying of ASD students in different educational contexts. The success of development and social adaptation of a child with ASD is also determined by the presence of individual correctional plans and programs, special equipment, special techniques, a differential approach to socio-psychological services, creativity and professionalism (correctional teachers and special psychologists). To implement the principles of consistency, systematic implementation of the correctional process, taking into account the personal development of the child, the programs are integrated depending on the characteristics of its development.
PECULIARITIES OF THE COGNITIVE SPHERE IN CHILDREN WITH DELAYED MENTAL DEVELOPMENT
Authors: Khartsiy E. M.
Published: June 2022

Purpose of the study — to study the level of development of attention, memory and thinking in children aged 4–6 years with mental retardation.The main objectives of the study: 1. To carry out a theoretical and methodological analysis of the content of the concepts of “cognitive sphere” and children with mental retardation in the scientific literature. 2. To clarify the features of the development of the cognitive sphere in preschoolers and preschoolers with mental retardation. 3. Empirically investigate the level of development of the cognitive sphere in preschoolers with mental retardation.Received further development of the idea of the possibility of the impactof correctional programs on the functions of the cognitive sphere ofpreschool children with mental retardation. The practical significance lies in the fact that the obtained research results, taking them into account in psycho-preventive, educational work with children with mental retardation, ensure the actualization and development of the cognitive spheres of preschoolers with mental retardation, optimize and accelerate their overall development, socialization and adaptation to the surrounding world. In our study, we used methods of collecting empirical information, including psychodiagnostic techniques: a method for diagnosing the state of visual memory “10 cards” of Luria;Wexler’s method “Consecutive pictures” to determine the formation of thought processes; method for diagnosing attention “Find and cross out” Nemov. The revealed data on the features of the development of the cognitive sphere of preschoolers with CRA can be used in lecture courses on age, pedagogical, social, special psychology, defectology, psychodiagnostics, psychocorrection by teachers of pedagogical universities.
Excel as an electronic method for determining thermal diffusivity from experimental data
Authors: Carneiro Camila Rodrigues , Neves Mateus Tomaz , Alhaji Adamu Muhammad , Sousa Rita de Cássia Superbi de
Published: June 2022

It is undoubted that, with industrial development, the thermophysical characterization of materials and substances, among other reasons, maximizes the performance of equipment and the efficiency of the most diverse unit operations. In these studies, related to thermal diffusivity, a property that is directly related to the heat transfer between materials, are increasingly recurrent. A simple and effective apparatus for estimating thermal diffusivity in an experimental and direct way was developed by Dickerson (1965), and since then it has been widely used in research related to this topic. However, considering that experimentally, a series of data is obtained related, for example, to the dimensions of the equipment, as well as the time values, and efficiently in order to obtain results that make it possible to infer as much information about the object of study as possible. Therefore, with this proposed work, the use of electronic spreadsheets, calculated for Excel data processing, from the experimental Microsoft software obtained by the apparatus. The functionality of the physical spreadsheets was verified through the electronic calculation resolution, in the manual form and in the demonstration of efficiency and agility of the computational method, in addition to the characterization of the potential for several materials or substances.
Democracia iliberal, populismo y Estado de Derecho
Authors: Barrio López Astrid
Published: June 2022

El artículo aborda la afectación de la democracia iliberal y del populismo sobre el Estado de Derecho. En primer lugar se discute acerca de la idoneidad de concepto de democracia iliberal que desde el punto de vista teórico y normativo resulta un oxímoron. En segundo lugar se aborda la vinculación entre la democracia liberal y el populismo asumiendo que el primero es un elemento consustancial. Por último se analizan las prácticas iliberales de algunas democracias modernas, sus pautas comunes y como ello incide en el Estado de Derecho

Recibido: 25.05.2022Aceptado: 14.06.2022