bluuebunny/crossref_metadata_2025 huggingface dataset:
Awareness about COVID-19 vaccine, its acceptance and hesitancy among the urban slum & non-slum population of Dharavi in Mumbai, India
Authors: Karan Gade  , Meeta Vashi  , Anish Sinha  , Shyam Pingle  , Mangala Gomare
Published: February 2023

Background: Vaccine apprehension poses a risk to global public health. Since an enormous global initiative was underway to create a vaccine to combat the COVID-19 pandemic, little is known about its acceptance in India. Understanding COVID-19 vaccine-related awareness, acceptance and non-acceptance of current and potential vaccines can aid in the development of strategies to improve the national mass vaccination programme. This study aims to determine vaccine related awareness, acceptance & awareness among Dharavi (Slum & Non-Slum) population of Mumbai for COVID-19 vaccine. Methods: A cross-sectional comparative study was conducted. Total 384 participants were surveyed, among them 192 were from Dharavi slum & 192 from Dharavi non-slum area. Responses to the questionnaire using Google form was filled in the field itself, by doing house to house survey using convenience sampling. Data on socio-demographic characters, COVID-19 vaccine awareness, acceptance & non-acceptance was collected. Results: Overall, out of 384 participants, 227 (59.1%) were having poor or very poor awareness & 157 (40.9%) were having average or above average awareness related to COVID-19 vaccines. Out of 192 slum residents 118 (61.5 %) & out of 192 residents of non-slum 132 (68.8%) were willing to get vaccinated & the difference is not statistically significant. Overall, out of 384 participants of Dharavi 250 (65.1%) were showing vaccine acceptance & 134 (34.9%) participants were showing vaccine hesitancy. Conclusion: Proportion of awareness & acceptance for COVID-19 vaccine varies & interlinked with socio-demographic characteristics like gender, educational level, religion & area of residency of the study population. COVID-19 vaccine acceptance was found to have significant association with awareness.
Effects of LytR on bacterial morphology in Streptococcus pyognes
Authors: Masaaki Minami  , Shunsuke Akahori  , Hiroshi Takase  , Michio Ohta
Published: February 2023

A robust cell envelope is the first line of defense in infectious pathogens when encountering host immune defenses. In Gram-positive bacteria, LytR-CpsA-Psr (LCP) family proteins play a major role in the synthesis and assembly of the cell envelope. The Gram-positive bacterium S. pyogenes causes a wide range of diseases from pharyngitis to septicemia, but the involvement of LytR in the synthesis and assembly of the cell wall envelope in this bacterium is not clear. Therefore, we investigated whether LytR of S. pyogenes, like LytR of other streptococci, is involved in cell wall formation. The lytR gene-deficient strains were used to investigate the bacteria's ability to form a chaining, drug sensitivity to penicillin G, an inhibitor of cell wall synthesis, bacterial biofilm formation, and the morphological structure of bacteria by transmission electron microscopy, and the expression of pbp2b, which encodes a penicillin-binding protein, compared with the wild-type strain. Our results showed that LytR-deficient strains had reduced bacterial chaining compared to wild-type strains. Compared to wild-type strains, LytR-deficient strains were also more drug sensitive to the cell wall synthesis inhibitor penicillin G. This genetic study was accompanied by increased expression of the pbp2b gene in the LytR-deficient strains. In addition, the LytR-deficient strain showed a reduced ability to form biofilms, and the lytR gene-deficient strain showed morphological irregularities with abnormal bacterial septa. These results indicate that the lytR gene is involved in cell wall synthesis in S. pyognes.
Determinants of sexuality development amongst adolescents in the faculty of nursing sciences, Niger Delta University, Amassoma, Bayelsa state, Nigeria
Authors: Letticia Ikiomoye Beredugo  , Esther Emarobebh Muojekwu  , Helen Idubamo Wankasi  , Tabitha Kutim Ishember  , Mary Arthur Ogon
Published: February 2023

Due to the growing number of sexually active adolescents worldwide, adolescent sexual development is critical. The purpose of this study was to look at the factors that influence sexual development in adolescents at Niger Delta University's Faculty of Nursing Sciences in Amassoma, Bayelsa State. Researchers used a descriptive survey design. Two research objectives were established to guide the study's course. The study's sample size was 160 adolescents chosen using a random sampling technique. The study included a self-structured questionnaire. The instrument's face and content validity were assessed. The test-retest approach was employed to determine the reliability of the questionnaire. According to the findings of this survey, adolescents have adequate awareness of sexual development because the majority of the respondents (152%) had heard about it. Friends 68(42.5%), social media 40(25%), school 32(20%), and parents 28(17.5%) were the sources of knowledge about sexuality development. Sex hormones were discovered to impact sexuality development in adolescents 130(81.25%), and estrogens and testosterones were revealed to be responsible for primary and secondary sexual characteristics in adolescents 90(56.25%). Furthermore, peer pressure impacts teenage sexuality development through counseling from peers 110(68.75%), dating relationships 120(75%), drinking and clubbing 116(72.5%), and sexual language usage 100(62.5%). However, psychosocial factor influencing sexuality development in adolescents includes; anxiety/depression 90(56.25%) self-esteem (low/high self-esteem) 83(51.88%), peer pressure 140(87.5%), parental influence 102(63.75%), alcoholism 104(65%), drug addiction 99(61.88%), pornography/masturbation 83(51.88%), religiosity 92(57.5%), culture 100(62.5%), mass media 121(75.63%) and nutrition 82(51.25%). In conclusion, the effects of hormones and psychosocial variables were identified as predictors of sexuality development in adolescents. It is Friends 68(42.5%), social media 40(25%), school 32(20%), and parents 28(17.5%) were the sources of knowledge about sexuality development. Sex hormones were discovered to impact sexuality development in adolescents 130(81.25%), and estrogens and testosterones were revealed to be responsible for primary and secondary sexual characteristics in adolescents 90(56.25%). Furthermore, peer pressure other factors have impacts on sexual development. However, it is recommended that Institutions should employ and retrain counselors through in-service training programs, capacity development seminars, and refresher courses on sexual behavior counseling among adolescents.
Evolution of patients with bipolar disorder according to pharmacological treatment Pediatric Hospital "Juan Manuel Márquez" 2009-2011
Authors: Mabel Aguilar Pérez  , Gladys Castillo Izquierdo  , Zenaida María Sáez  , Juan Aguilar Valdés  , Alina Leyva Castell  , Mairim Escalona Gutiérrez
Published: February 2023

To know the evolution, according to the pharmacological treatment received, of the patients admitted to the Psychiatric Ward of the "Juan Manuel Márquez" Paediatric Hospital, with Bipolar Disorder (TB) in the period from January 2009 to December 2011, the present study. The objective is to identify the evolution of the patients three, six and twelve months after hospital discharge according to the pharmacological treatment used. A retrospective longitudinal descriptive study was carried out between May 2012 and May 2013. 81 hospitalized patients with TB were studied. The source of information was their medical records and a semi-structured interview. The data was processed in SPSS version 15 and the results are presented in statistical tables. Three months after hospital discharge, the highest percentage of patients with satisfactory clinical status had treatment with Haloperidol alone, in second place Risperdal and Carbamazepine and in third place the combination of Haloperidol and Magnesium Valproate (Mg), while Six months was Haloperidol alone, followed by the combination of Olanzapine and Lithium Carbonate, Risperdal and Mg Valproate, one year after hospital discharge the combination of Olanzapine and Lithium Carbonate was found first, followed by Risperdal with Carbamazepine and of quetiapine alone. The treatments most associated with satisfactory clinical status were: Haloperidol alone, Quetiapine alone, as well as the combinations of Risperdal and Carbamazepine, Risperdal and Mg Valproate, Olanzapine and Lithium Carbonate, and Haloperidol with Mg Valproate.
Development and validation of HPLC method for ximenynic acid in semisolid dosage formulation
Authors: Rakesh Shrirang Shivatare  , Dheeraj Hanumansingh Nagore  , Rakesh kumar Jat
Published: February 2023

A novel analytical technique and validation study were developed to determine the concentration of ximenynic acid (XMA) in semisolid dosage formulations (SDF) such as cream, gel, lotion, etc. The procedure makes use of reverse-phase high-performance liquid chromatography (HPLC). A Phenomenex Luna Column 5 (4.6 x 250 mm) was used for the analysis, using acetonitrile as the mobile phase, sodium dihydrogen phosphate monohydrate as the stationary phase, and 229 nm detection at 30 degrees Celsius. In spite of the presence of additional compounds, their presence had no effect on the detection of XMA in SDF. As part of validating this HPLC technique, a number of tests were performed to evaluate its specificity, linearity, accuracy, precision, and durability. International Conference on Harmonization standards were used to determine whether the method was adequate (ICH). Because it is simple to implement and produces reproducible results, the presented HPLC approach has the potential to be utilized in industry to standardize herbs and Phytomedicines. Because XMA has the potential to be a game-changing method of treating ageing, its advancement may benefit the pharmaceutical and cosmetics sectors.
Insulin like growth factor 1 (IGF-1) and IGF binding proteins in obese pregnant women and their babies: Potential effects on placental function and fetal growth
Authors: Ashraf Soliman  , Noor Hamed  , Fawzia Alyafei  , Nada Alaaraj  , Shayma Ahmad  , Maya Itani  , Nada Soliman
Published: February 2023

Introduction: The placenta expresses significant amounts of insulin and IGF1 receptors at distinct locations on both fetal and maternal surfaces. This makes the IGF1 and the insulin receptor accessible to fetal and/or maternal insulin, IGF1 and IGF2. IGFs are involved in the receptor-mediated regulation of placental growth and transport, and placental angiogenesis. Maternal obesity during gestation mediates significant changes in the metabolism of mothers, placentas as well as fetal growth. Objectives: In obese women. the role of the insulin like growth factor system IGFs, IGF receptors, IGF-binding proteins (IGFBPs) and IGFBP proteases during gestation, and their effect on placental growth and fetal anthropometric changes need further clarification. In this update we reviewed the literature on the detected changes in the maternal and fetal IGFs in relation to placental growth and function and to fetal growth and newborn size in pregnant obese mothers. Eighteen research articles fitted the criteria of this update. Results: Twenty-three research papers were including 2817 pregnant obese and non-obese women (controls) and their babies were selected and reviewed. Results showed that obesity and excessive nutrient intake during gestation increase maternal IGF1and decreases IGBP1. Increased maternal IGF1 and/or its availability due to decreased IGFBP1 can increase the size (weight) and development of the placenta, stimulate mTOR signaling which stimulates protein synthesis, mitochondrial function, and upregulate specific placental amino acid transporter isoforms (amino acids transport), GLUT-1, (glucose transport) and possibly lipid transport to the fetus which can induce fetal IGF1 secretion and lead to overgrowth. Conclusions: In obese women during pregnancy, increased level of IGF1 and/or its availability due to decreased IGFBP1 can increase the size (weight) and development of the placenta, stimulate mTOR signaling which stimulates protein synthesis, mitochondrial function, and upregulate placental transport of amino acids, glucose and possibly fatty acids.
PKM PELATIHAN PEMBUATAN ECOPRINT UNTUK IBU-IBU PKK BERDAMPAK COVID-19 DI KOMPLEK BCL HAJIMENA LAMPUNG SELATAN
Authors: Putra Dedi , Irawati Anik , Swissia Pebrina
Published: February 2023

Teknik eco print merupakan salah salah satu alternatif industri rumahan berupa produk tekstil yang ramah lingkungan Ecoprint adalah batik yang menggunaka daun, bunga atau kayu yang dapat mengeluarkan warna. Ibu-ibu PKK Kompleks BCL Lamsel yang belum memiliki ketrampilan dapat memanfaatkan waktu luangnya untuk meningkatkan pendapatan melalui kegiatan pengabdian masyarakat dalam bentuk pelatihan pembuatan ecoprint. Tujuan pengabdian ini adalah untuk meningkatkan pengetahuan dan ketrampilan kepada mitra dalam pembuatan ecoprint 1) sosialisasi kepada ibu-ibu tentang eco print, 2) pelatihan kepada ibu-ibu dalam pembuatan ecoprint. Tahap sosialisasi dilakukan dengan mensosialisasikan ecoprint sebagai produk ramah lingkungan dan mengenalkan bahan-bahan untuk membuat ecoprint. Pelatihan pembuatan ecoprint menggunakan teknik steam melalui tahap-tahap: scouring (pencucian kain), mordanting (perendaman kain pada larutan mordan dan larutan pewarna alami), penyusunan daun di atas kain, pengukusan, dan fiksasi (pengeringan). Hasil yang diperoleh, mitra memiliki peningkatan ketrampilan membuat ecoprint dan memperoleh pendapatan yang lebih baik.
Pemberdayaan Pembuatan Pakan Ternak Fermentasi Berbasis Limbah Pertanian di Desa Labokong Kecamatan Donri-Donri Kabupaten Soppeng
Authors: Sema
Published: February 2023

Limbah pertanian merupakan limbah yang dapat dijadikan sebagai sumber pakan ternak. Limbah ini cukup potensial karena ketersedian bahan bakunya melimpah namun pemanfaatannya belum dilaksanakan secara optimal guna menunjang kebutuhan hidup masyarakat oleh karena itu dilaksanakan kegiatan pemberdayaan masyarakat dengan pembuatan pakan ternak dari batang pisang, Tujuan dari kegiatan  ini yaitu untuk menggambarkan dan menguraikan keadaan atau fakta-fakta  tentang pemanfaatan limbah pertanian sebagai pakan fermentasi di Desa Labokong Kecamatan Donri-Donri Kabupaten Soppeng. Metode pendekatan digunakan adalah sosialisasi program, penyuluhan, pelatihan secara teori dan praktek, serta pendampingan dalam pembuatan pakan ternak dari limbah batang pisang. Hasil kegiatan menunjukkan bahwa keterampilan sosial memiliki kerja sama yang baik dalam menyelesaikan tugas. Bahkan di luar kelas keterampilan sudah menunjukkan bahwa mereka memiliki keterampilan sosial yang baik. Pakan ternak hasil fermentasi dari batang pisang sangat berguna untuk mengatasi kelangkaan pakan utamanya pada musim kemarau dan hasil uji coba pada ternak sangat menyukai pakan fermentasi yang dibuat dibanding pakan tanpa fermentasi, sedangkan kegiatan penyuluhan dan pelatihan berjalan dengan baik dan bermanfaat untuk mewujudkan kemandirian pakan  berbasis limbah pertanian. Kegiatan pendampingan masih diperlukan untuk keberlanjutan program. Pakan ternak batang pisang hasil fermentasi mempunyai nilai nutrisi lebih baik dan lebih disukai ternak sehingga dapat meningkatkan produksi ternak dari bertambahnya bobot badan ternak.
PKM Bahan Ajar Berbasis Website Bagi Guru SMP Negeri Di Kecamatan Sesean, Rantepao, Toraja Utara
Authors: Sampelolo Rigel , Karuru Perdy
Published: February 2023

Program Kemitraan Masyarakat (PKM) ini bermitra dengan guru SMP Negeri di Kecamatan Sesean, Rantepao, Toraja Utara sebagai Mitra sasaran masyarakat yang tidak produktif secara ekonomi. Tujuan Pelaksanaan  program PKM ini yaitu untuk menyelesaikan rangkaian permasalahan pedagogis dan teknologi pada Mitra Sasaran terkait penyediaan bahan atau Materi ajar berbasis Website. Permasalahan yang menjadi fokus pada PKM ini berangkat dari temuan pada studi pendahuluan yang dilakukan pada awal tahun 2021. Adapun permasalahan yang dimaksud yaitu belum tersedianya  materi ajar  dalam bentuk website pada Mitra Sasaran. Metode pelaksanaan ialah dengan sosialisasi, pelatihan, pendampingan, dan evaluasi. Hasil dari kegiatan pengabdian masyarakat yang melibatkan 10 orang guru ini di antaranya: (1) guru mampu mendesain bahan ajar berbasis website, (2) guru dapat memanfaatkan teknologi informasi dan komunikasi dalam pembelajaran yang diampu, (3)  guru bisa mengembangkan kemampuan lebih optimal dalam pembuatan bahan ajar di sekolah dengan  lebih baik
Peningkatan Mutu Kurikulum Sekolah di SD melalui K-13
Authors: Badawi Subiha , Santaria Rustan
Published: February 2023

Penelitian ini bertujuan untuk mendeskripsikan dan memperoleh gambaran tentang peningkatan mutu kurikulum sekolah di SD melalui K-13. Penelitian ini adalah jenis penelitian kepustakaan (Liberary Reserch), dengan pendekatan konten isi. Penulis berkesimpulan bahwa peningkatan mutu kurikulum Sekolah Dasar melalui K-13 diarahkan pada peningkatan peran kepala sekolah yang lebih optimal, adanya kompetensi khusus yang dimiliki oleh guru tentang kurikulum 2013 (K-13), peningkatan kompetensi siswa baik dalam pengetahuan, keterampilan maupun karakter siswa, dan terwujudnya proses belajar yang efektif.
Analisis Tingkat Pemahaman Materi Sanitasi Lingkungan dengan Film Dokumenter pada Mahasiswa
Authors: Asri Asri
Published: February 2023

Tujuan penelitian adalah sebagai upaya untuk meningkatkan pengetahuan tentang pencemaran lingkungan berupa limbah sanitasi, sehingga Mahasiswa Pendidikan Biologi Universitas Cokroaminoto Paopo diberikan pembelajaran dengan menggunakan film dokumenter sebanyak 31 orang. Langkah penelitian adalah metode tindakan pembuatan kit film dokumenter yang divalidasi oleh ahli media pembelajaran agar layak digunakan dan soal evaluasi menggunakan software Google Form untuk dilakukan secara online oleh siswa setelah proses pembelajaran. Kemampuan memahami materi siswa dalam kategori sedang sebanyak 22 orang dari total sampel 31 orang, hasil belajar kemampuan siswa dalam memahami materi penyehatan lingkungan berada pada kategori sedang dengan persentase 71 persen. Kategori rendah memahami materi sebanyak 9 orang dengan persentase 29 persen yang artinya kemampuan memahami materi penyehatan lingkungan dengan menggunakan film dokumenter kurang baik sehingga mendapatkan hasil kategori rendah.
Meningkatkan Pemahaman Konsep Siswa Sekolah Dasar melalui Pendekatan Keterampilan Proses
Authors: Erni Erni
Published: February 2023

Penelitian ini adalah Penelitian Tindakan Kelas yang bertujuan untuk mengetahui peningkatan pemahaman konsep perubahan sifat benda melalui pendekatan keterampilan proses pada siswa kelas V SDN 31 Salotellue Kota Palopo. Subjek penelitian ini adalah siswa kelas V yang berjumlah 26 orang, 14 laki-laki dan 12 perempuan. Teknik pengumpulan data yang digunakan adalah observasi, tes, wawancara dan dokumentasi. Hasil penelitian menunjukkan pada siklus I kemampuan pemahaman konsep siswa mendapat nilai rata-rata sebesar 51,5% dan berada pada kategori sangat rendah dengan pencapaian ketuntasan klasikal hanya 46,2%. Pada siklus II tingkat kemampuan pemahaman konsep siswa meningkat menjadi 87% dan berada pada kategori tinggi dengan ketuntasan klasikal sebesar 88,5%. Hasil tersebut menunjukkan bahwa pemahaman konsep perubahan sifat benda dapat meningkat melalui pendekatan keterampilan pada siswa kelas V SDN 31 Salotellue Kota Palopo
Identifikasi Kesalahan Mahasiswa dalam Menyelesaikan Soal-Soal Komposisi Fungsi Pada Mata Kuliah Kalkulus Dasar
Authors: Fitri Fitriani A.
Published: February 2023

Penelitian ini bertujuan untuk mengidentifikasi kesalahan dalam menyelesaikan soal fungsi komposisi oleh mahasiswa Pendidikan Guru Sekolah Dasar Universitas Cokroaminoto Palopo. Jenis penelitian ini adalah penelitian deskriptif, dengan memberikan 2 jenis soal kepada 43 Mahasiswa. Hasil jawaban mahasiswa kemudian dianalisis dan dikelompokkan ke dalam kelasahan konsep dan kelasahan prosedural. Kesalahan konsep seperti penentuan fungsi f (x) dari fungsi komposisi yang f(x) dan f o g (x) sudah diketahui, dan miskonsepsi terhadap fungsi komposisi f o g (x) = g o f (x). Sedangkan kesalahan prosedural seperti kesalahan dalam melakukan perhitungan atau komputasi, dan kesalahan dalam melakukan operasi aljabar.
Cisgênero e Cissexual
Authors: Cava Peter , Braga Patrick de Almeida Trindade , Neto Rubens Mascarenhas , Zanoli Vinícius
Published: February 2023

Trata-se da tradução do texto de Peter Cava, Cisgender and Cissexual, originalmente publicado em "The Wiley Blackwell Encyclopaedia of Gender and Sexuality Studies" , editado por Nancy A. Naples, no ano de 2016. A tradução foi feita por Patrick de Almeida Trindade Braga com revisão técnica de Rubens Mascarenhas Neto e Vinícius Zanoli.
Valori dell’Olimpismo e pregnanza giuridica nella geopolitica dello sport
Authors: Melica Luigi
Published: February 2023

Il conflitto russo-ucraino ha impattato anche sul mondo dello sport, costringendo i vertici della governance sportiva mondiale ad assumere decisioni forti, nonostante il principio di neutralità politica sancita dalla Carta olimpica. Tuttavia, le stesse istituzioni sportive continuano a tollerare visioni dello sport fortemente in controtendenza rispetto alla visione olimpica, come quella promossa dalla Federazione russa, decisamente orientata verso la componente marziale dello sport. Il contributo indaga sulla pregnanza giuridica che può (o dovrebbe) accordarsi ai valori dell’Olimpismo espressi nella Carta olimpica, in modo da superare l’empasse per cui questi valori sono evidentemente proclamati, ma la loro applicazione da parte delle istituzioni sportive resta incerta, in virtù del peso che le prese di posizione potrebbero comportare sugli equilibri geopolitici su cui lo sport impatta.
L’utilizzo degli animali nello sport – il d.lgs. 36/2021 le criticità di una normativa attesa e dovuta
Authors: Di Paolo Tommaso , Toniato Martina
Published: February 2023

Il decreto legislativo n. 36 del 28 febbraio 2021 opera un cambiamento cardinale, seppur non inatteso, che ha visto la mano normativa affrontare per la prima volta in modo deciso il ruolo degli animali nello sport. Un’apertura che deriva da conoscenze scientifiche, posizioni europee e interventi di federazioni ed enti di promozione sportiva, che porta con sé alcune sostanziali perplessità sulla concreta attuazione futura. L’elaborato affronta i cambiamenti della dottrina e della normativa di settore alla luce delle nuove conoscenze in ambito di benessere animale, ponendo l’accento sulle problematiche valutative e sulla condizione giuridica dell’animale inteso non solo come essere senziente bensì come atleta. Non più una semplice res, come peraltro afferma ancor oggi il nostro codice civile, piuttosto il riconoscimento di un soggetto portatore di autonomi interessi che viene considerato aldilà della longa manus della persona fisica che lo detiene.
Scientist and Leader. Nikolay Gennadiyevich Basov 1922-2001
Authors:   P.N. Lebedev Physical Institute RAS, 119991, Russia, Moscow, Leninskiy pr., 53, Vinogradov A.V. , Gubin M.A ,   P.N. Lebedev Physical Institute RAS, 119991, Russia, Moscow, Leninskiy pr., 53, Kuznetzov A.P. ,   National Research Nuclear University “MEPHI”, 115409, Russia, Moscow, Kashirskoe highway, 31
Published: February 2023

Like the titans of the Renaissance, N.G. Basov represented the heroic era of our science. He was both the leader and the scientist who coexisted in him in the closest possible way. You can say that he was an armchair scientist who defines, thinks over and solves scientific problems one on one. In 1952, thirty-year-old N.G. Basov was the first to point out the fundamental possibility of creating a molecular generator. In the next four years, he carried out work on its theoretical justification and experimental implementation working with the participation of a small group of young scientists, the eldest of whom was A.M. Prokhorov. Already in 1958, N.G. Basov started to organize work in the field of quantum electronics at the Lebedev Physical Institute under the auspices of the USSR Academy of Sciences, and in 1961 he delivered a concept paper on this subject at the All-Union Meeting of Scientists in the Kremlin. The article uses materials that appeared in the scientific literature and the media timed to the centenary of N.G. Basov, as well as impressions of joint work and meetings with him at the Lebedev Physical Institute and MEPhI.
ON THE INFLUENCE OF THE DISPERSION OF ABSORPTION ON THE TIME DEPENDENCE OF A HOLONOMIC NARROW-BAND SIGNAL IN A DISPERSIVE MEDIUM FAR FROM THE POINT OF RADIATION
Authors:   Samara State Technical University, 443001, Russian Federation, Samara, Molodogvardeiskaya str., 244, Bukhman N.S. , Kulikova A.V. ,   Samara State Technical University, 443001, Russian Federation, Samara, Molodogvardeiskaya str., 244
Published: February 2023

It is well known that when a narrow-band signal propagates in any medium with a sufficient length of the path, the amplitude-frequency spectrum of the signal inevitably begins to deform due to the dispersion of the absorption coefficient of the medium, that is, due to the dependence of the absorption coefficient on frequency. Therefore, the time dependence of the signal «at infinity» significantly depends not only on the dispersion of the real part of refractive index, but also on the dispersion of the absorption. In this work, we consider the propagation and distortion of a narrow-band holonomic signal in a homogeneous dispersive medium (by the example of a weakly collisional plasma) taking into account the absorption dispersion. It turns out that the absorption dispersion manifests itself differently for different types of holonomic signals – for holonomic signals with a limited spectrum, the spectrum of which is identically equal to zero outside a certain spectral interval, and for holonomic signals with an unlimited spectrum, the spectrum of which does not vanish with increasing frequency. It is shown that for holonomic signals with an unlimited starting spectrum, the absorption dispersion with increasing path length leads to a shift in the carrier frequency towards lower absorption and to normalization of the spectrum intensity, and hence to normalization of the time dependence of the signal, which becomes Gaussian at infinity. At the same time the signal continues to remain narrow-band. For holonomic signals with a limited spectrum, the absorption dispersion leads to a narrowing of the spectrum, which «presses» it against the boundary of the original signal spectrum. This time, as in the case of signals with an unlimited spectrum, the “standardization” of the time dependence of the signal also occurs, but now the time dependence of an arbitrary signal turns out to be not Gaussian, but “Lorentzian”.
Anteseden dan Konsekuensi Brand Trust
Authors: Keyla Azzahra Putri Alisya , Astarini Dyah
Published: February 2023

Penelitian ini bertujuan menguji dan menganalisis faktor yang mempengaruhi brand trust dan konsekuensi yang ditimbulkan adalah brand loyalty. Sampel yang digunakan dalam penelitian ini berjumlah 230 Responden. Teknik pengambilan sampel yang digunakan adalah purposive sampling. Data dianalisis menggunakan metode Structural Equation Model (SEM). Hasil penelitian ini menunjukkan terdapat pengaruh positif advertisement dan social network sevice content terhadap customer engagement. Terdapat pengaruh positif advertisement dan social network service content terhadap brand trust. Terdapat pengaruh positif customer engagement terhadap brand trust. Terdapat pengaruh positif customer engagement dan brand trust terhadap brand loyalty.
Sistem Informasi Prediksi Kelulusan Menggunakan Metode Naive Bayes Classifer (Studi Kasus: Prodi Pendidikan Teknik Informatika)
Authors: Diska Kemal Refta , Budayawan Khairi
Published: February 2023

Prediksi (prediction) adalah kegiatan memprediksi apa yang akan terjadi di masa yang akan datang. Karena masalah pengambilan keputusan adalah masalah yang harus dihadapi, demikian juga peramalan. Karena prediksi sangat erat kaitannya dengan pengambilan keputusan. Prediksi kelulusan mahasiswa merupakan upaya untuk membantu mahasiswa mengetahui status kelulusannya. Metode yang digunakan yaitu metode prototyping merupakan salah satu metode pengembangan perangkat lunak yang menggunakan pendekatan untuk membuat rancangan dengan cepat dan bertahap sehingga dapat segera dievaluasi oleh calon pengguna/klien. Aplikasi prediksi mahasiswa ini diuji menggunakan data mahasiswa PTI angkatan 2014 dan 2015 sebagai data training berjumlah 94 data, dan data mahasiswa angkatan 2016 sebagai data testing berjumlah 46 data. Pada aplikasi ini klasifikasi naïve bayes classifier digunakan untuk melakukan klasifikasi data berdasarkan hasil studi 6 semester dan total sks. Hasil klasifikasi dari aplikasi ini menyatakan bahwa dari 46 data testing memperoleh hasil accuracy 82,61%, precision 91,66%, recall 61,11%. Aplikasi ini dapat membantu memprediksi hasil kelulusan mahasiswa tepat waktu atau tidak tepat waktu berdasarkan hasil studi.
Aplique modelos de linguagem grandes pré-treinados em pesquisas financeiras com IA
Authors: Kim Donghyun
Published: February 2023

No passado recente, o uso de modelos de linguagem pré-treinados (PLMs) ganhou imensa popularidade para tarefas de processamento de linguagem natural (NLP). Este artigo avalia as capacidades desses modelos no setor financeiro, juntamente com os obstáculos que eles enfrentam nesse domínio. O artigo também avalia a transparência desses modelos e as questões éticas relacionadas ao seu uso em finanças. Nosso estudo mostra que os PLMs têm o potencial de transformar a forma como os dados financeiros são analisados e processados. No entanto, é crucial abordar os desafios e as preocupações éticas associadas à sua implementação para garantir que sejam usados de forma ética e responsável. Estudos futuros se concentrarão em melhorar os modelos para gerenciar a instabilidade dos dados financeiros, reduzir o viés nos dados de treinamento e oferecer previsões transparentes. Em conclusão, acreditamos que o avanço da IA em finanças será determinado pelo crescimento e implementação de modelos de linguagem pré-treinados.
Differential expression of LAMC2 in pancreatic cancer.
Authors: Mamoor Shahan
Published: February 2023

Cancer is a leading cause of death and pancreatic cancer is among the most lethal cancers (1, 2). We mined published microarray datasets (3, 4) to determine in an unbiased fashion and at the level of the transcriptome genes most differentially expressed in the primary tumors of patients with pancreatic cancer, pancreatic adenocarcinoma (PDAC). We found significant differential expression of the gene encoding laminin subunit gamma 2, LAMC2, when comparing pancreatic tumors to the tissue of origin, the pancreas. LAMC2 mRNA was present at significantly higher quantities in tumors of the pancreas as compared to normal pancreatic tissue. Analysis of human survival data revealed that expression of LAMC2 in pancreatic tumors was correlated with overall survival in patients with pancreatic adenocarcinoma. LAMC2 expression changes may be important for the initiation or progression of human PDAC.
Housing and welfare reform, and the suburbanisation of poverty in UK cities, 2011-20
Authors: Bailey Nick , livingston mark , Chi Bin
Published: February 2023

The suburbanisation of poverty has been noted in many advanced industrial nations including the UK. Theory focuses on economic and labour market restructuring combined with processes of market- and/or state-led housing change. This paper examines the contributions of housing and welfare reforms. In the UK, housing policy has driven low-income households increasingly to find accommodation in the private rental sector at the same time that welfare reforms have constrained the rents these households can afford. This paper traces the spatial consequence of these reforms, drawing on a novel combination of Government data and a database of private rental adverts. Up to 2011, the shift from social to private renting for low-income households was relatively neutral in its impacts on suburbanisation. Since then, low-income households in private renting have been increasingly pushed to less central locations as rents in more central areas have risen faster. The role played by housing and welfare policy in the suburbanisation of poverty needs wider consideration.
Investigation of Impact and Energy Absorption Properties in Glass Laminate Aluminum Reinforced Epoxy (GLARE)
Authors: Nikahd Shahram
Published: February 2023

In recent years, fiber-metal layer (FML) composites have attracted interests of aero-space and defense industries due to their unique properties such as good impact resistance and toughness. The most common class of these composites is GLARE which includes aluminum, as metal sheet, and glass fiber-enhanced epoxy. I this study, impact resistance and energy absorption of GLARE sheets are investigated. Different damage mechanisms such as plastic deformation of metal layer, matrix fracture, fiber failure, separation and layering of composite layers and separation of metal layer from composite were studied. Through application of finite element method in ABAQUS software, different impact energies, different mass blows and various layer thicknesses and arrangements were analyzed. The results show that by increasing the blow energy, the plastic strain of the metal sheet will be increased and fibers would be damaged and cracked. Also, it was observed that, depending on the amount of energy and geometrical properties of the sheet and impact inducer, the damage mechanism would be different. Finally, it was indicated that GLARE 3 exhibited better impact resistance in comparison with GLARE 5.
Differential expression of MICAL2 in pancreatic cancer.
Authors: Mamoor Shahan
Published: February 2023

Cancer is a leading cause of death and pancreatic cancer is among the most lethal cancers (1, 2). We mined published microarray datasets (3, 4) to determine in an unbiased fashion and at the level of the transcriptome genes most differentially expressed in the primary tumors of patients with pancreatic cancer, pancreatic adenocarcinoma (PDAC). We found significant differential expression of the gene encoding microtubule associated monooxygenase, calponin and LIM domain-containing 2, MICAL2, when comparing pancreatic tumors to the tissue of origin, the pancreas. MICAL2 mRNA was present at significantly higher quantities in tumors of the pancreas as compared to normal pancreatic tissue. Analysis of human survival data revealed that expression of MICAL2 in pancreatic tumors was correlated with overall survival in patients with pancreatic adenocarcinoma. MICAL2 expression changes may be important for the initiation or progression of human PDAC.
教育効率を改善するための事前訓練された大規模言語モデルの可能性
Authors: Kim Donghyun
Published: February 2023

自然言語処理 (NLP) における事前学習済み言語モデル (PLM) のアプリケーションは、さまざまな NLP タスクおよび公開ベンチマークでの優れたパフォーマンスで広く認められています。 PLM を教育に統合すると、学習と教育の実施方法が変わる可能性があります。 ただし、このような統合に伴う利点と欠点の両方を比較検討することが重要です。 PLM の利点を最大限に活用し、悪影響を最小限に抑えるには、PLM を教育に組み込む際に、慎重かつ責任あるアプローチが必要です。 このホワイト ペーパーでは、教育で PLM を使用することの長所と短所を詳しく説明し、将来の進歩のためのガイダンスを提供します。
Dinamika filsafat hukum di indonesia
Authors: Ihsan Adithia ilal
Published: February 2023

Penulis dalam makalah ini mencoba untuk menyelidiki dan menggambarkan pemikiran Bagaimana Dinamika Filsafat hukum di Indonesia. Dinamika adalah sesuatu yang mengandung arti tenaga kekuatan, selalu bergerak, berkembang dan dapat menyesuaikan diri secara memadai terhadap keadaan serta pembaharuan pemikiran masyarakat. filsafat hukum berkaitan erat dengan hidup dan penghidupan hukum. Di Indonesia hukum tidak cukup berperan sebagai alat, tetapi juga sebagai sarana pembaruan masyarakat. Hukum dalam konsep Mochtar tidak diartikan sebagai “alat” tetapi sebagai “sarana” pembaruan masyarakat.
antropologi menata kehidupan
Authors: adrian yaumil restu
Published: February 2023

antropologi menata kehidupan manusia
Potentiels des grands modèles de langage pré-entraînés pour améliorer l'efficacité de l'éducation
Authors: Kim Donghyun
Published: February 2023

L'application de modèles de langage pré-entraînés (PLM) dans le traitement du langage naturel (TAL) a été largement reconnue pour ses performances exceptionnelles dans diverses tâches de TAL et dans des benchmarks publics. L'intégration des PLM dans l'éducation a la possibilité de transformer la façon dont l'apprentissage et l'enseignement sont menés. Cependant, il est crucial de peser à la fois les avantages et les inconvénients qui peuvent accompagner une telle intégration. Pour tirer pleinement parti des PLM et minimiser les impacts négatifs, une approche prudente et responsable est nécessaire lors de l'intégration des PLM dans l'éducation. Ce document se penche sur les avantages et les inconvénients de l'utilisation des PLM dans l'éducation et offre des conseils pour les progrès futurs.
Tugas makalah nadhif
Authors: luchan nadhif musaid
Published: February 2023

NFilsafat hukum merupakan obyek materi filsafat. Filsafat hukum senantiasa ada kaitannya dengan filsafat moral dan sistem nilai. Filsafat hukum dalam perkembangannya senantiasa berhubungan dengan masalah kekuasaan negara dan kaitan dengan ilmu hukum, tidak lepas dari persoalan hubungan teori hukum dan dogmatika hukum.
Potenzialità di modelli linguistici di grandi dimensioni pre-addestrati per migliorare l'efficienza dell'istruzione
Authors: Kim Donghyun
Published: February 2023

L'applicazione dei modelli linguistici preaddestrati (PLM) nell'elaborazione del linguaggio naturale (NLP) ha ottenuto un ampio riconoscimento per le sue eccezionali prestazioni in vari compiti di PNL e benchmark pubblici. L'integrazione dei PLM nell'istruzione ha la possibilità di trasformare il modo in cui vengono condotti l'apprendimento e l'insegnamento. Tuttavia, è fondamentale soppesare sia i vantaggi che gli svantaggi che possono accompagnare tale integrazione. Per sfruttare appieno i vantaggi dei PLM e ridurre al minimo gli impatti negativi, è necessario un approccio attento e responsabile quando si incorporano i PLM nell'istruzione. Questo documento approfondisce i pro e i contro dell'utilizzo dei PLM nell'istruzione e offre una guida per i progressi futuri.
Social history of micro-chips; Japanese 'imports' (Supplement I:28)
Authors: Akmut Camille
Published: February 2023

Supplement to the Historiography (of computer science and tech.) / Chip making in Taiwan and South Korea + Princess Crown and Touge Max G
Appliquer des modèles de grands langages pré-entraînés à la recherche financière basée sur l'IA
Authors: Kim Donghyun
Published: February 2023

Dans un passé récent, l'utilisation de modèles de langage pré-entraînés (PLM) a acquis une immense popularité pour les tâches de traitement du langage naturel (TAL). Cet article évalue les capacités de ces modèles dans le secteur financier, ainsi que les obstacles auxquels ils sont confrontés dans ce domaine. L'article évalue également la transparence de ces modèles et les enjeux éthiques liés à leur utilisation en finance. Notre étude montre que les PLM ont le potentiel de transformer la façon dont les données financières sont analysées et traitées. Cependant, il est crucial de relever les défis et les préoccupations éthiques associés à leur mise en œuvre pour s'assurer qu'ils sont utilisés de manière éthique et responsable. Les études futures se concentreront sur l'amélioration des modèles pour gérer l'instabilité des données financières, réduire les biais dans les données de formation et offrir des prévisions transparentes. En conclusion, nous pensons que l'avancement de l'IA dans la finance sera déterminé par la croissance et la mise en œuvre de modèles de langage pré-entraînés.
Tugas makalah
Authors: luchan nadhif musaid
Published: February 2023

Filsafat hukum merupakan obyek materi filsafat. Filsafat hukum senantiasa ada kaitannya dengan filsafat moral dan sistem nilai. Filsafat hukum dalam perkembangannya senantiasa berhubungan dengan masalah kekuasaan negara dan kaitan dengan ilmu hukum, tidak lepas dari persoalan hubungan teori hukum dan dogmatika hukum.
Wenden Sie vortrainierte große Sprachmodelle auf KI-gestützte Finanzforschung an
Authors: Kim Donghyun
Published: February 2023

In der jüngeren Vergangenheit hat die Verwendung von vortrainierten Sprachmodellen (PLMs) für Aufgaben der Verarbeitung natürlicher Sprache (NLP) immense Popularität erlangt. Dieses Papier bewertet die Fähigkeiten dieser Modelle im Finanzsektor, zusammen mit den Hindernissen, denen sie in diesem Bereich gegenüberstehen. Das Papier bewertet auch die Transparenz dieser Modelle und die ethischen Fragen im Zusammenhang mit ihrer Verwendung im Finanzwesen. Unsere Studie zeigt, dass PLMs das Potenzial haben, die Art und Weise, wie Finanzdaten analysiert und verarbeitet werden, zu verändern. Es ist jedoch entscheidend, die Herausforderungen und ethischen Bedenken anzugehen, die mit ihrer Umsetzung verbunden sind, um sicherzustellen, dass sie ethisch und verantwortungsbewusst verwendet werden. Zukünftige Studien werden sich auf die Verbesserung der Modelle konzentrieren, um die Instabilität von Finanzdaten zu bewältigen, Verzerrungen in den Trainingsdaten zu reduzieren und transparente Vorhersagen zu bieten. Zusammenfassend glauben wir, dass die Weiterentwicklung der KI im Finanzwesen durch das Wachstum und die Implementierung vortrainierter Sprachmodelle bestimmt wird.
Differential expression of PLCD3 in pancreatic cancer.
Authors: Mamoor Shahan
Published: February 2023

Cancer is a leading cause of death and pancreatic cancer is among the most lethal cancers (1, 2). We mined published microarray datasets (3, 4) to determine in an unbiased fashion and at the level of the transcriptome genes most differentially expressed in the primary tumors of patients with pancreatic cancer, pancreatic adenocarcinoma (PDAC). We found significant differential expression of the gene encoding phospholipase C delta 3, PLCD3, when comparing pancreatic tumors to the tissue of origin, the pancreas. PLCD3 mRNA was present at significantly higher quantities in tumors of the pancreas as compared to normal pancreatic tissue. Analysis of human survival data revealed that expression of PLCD3 in pancreatic tumors was correlated with overall survival in patients with pancreatic adenocarcinoma. PLCD3 expression changes may be important for the initiation or progression of human PDAC.
Potenziale vortrainierter großer Sprachmodelle zur Verbesserung der Bildungseffizienz
Authors: Kim Donghyun
Published: February 2023

Die Anwendung vortrainierter Sprachmodelle (PLMs) in der Verarbeitung natürlicher Sprache (NLP) hat breite Anerkennung für ihre herausragende Leistung bei verschiedenen NLP-Aufgaben und öffentlichen Benchmarks erlangt. Die Integration von PLMs in die Bildung hat die Möglichkeit, die Art und Weise, wie Lernen und Lehren durchgeführt werden, zu verändern. Es ist jedoch entscheidend, sowohl die Vor- als auch die Nachteile abzuwägen, die mit einer solchen Integration einhergehen können. Um die Vorteile von PLMs voll auszuschöpfen und negative Auswirkungen zu minimieren, ist ein sorgfältiger und verantwortungsvoller Ansatz erforderlich, wenn PLMs in die Bildung integriert werden. Dieses Whitepaper befasst sich mit den Vor- und Nachteilen des Einsatzes von PLMs im Bildungswesen und bietet Leitlinien für zukünftige Fortschritte.
Editorial Vol.10(1)
Authors: Gautam Shreedhar
Published: February 2023

Not available.
Livelihood Impacts of Kulekhani Hydropower Station-II Project on Surrounding Community
Authors: Dahal Ananta Raj
Published: February 2023

This research article tries to analyse the livelihood impact of the Kulekhani Hydropower project for the local people. From the use of questioner survey method of the sample area population information were captured. This information had analysed through the descriptive and infernal statistical methods by the help of SPSS software for information gathering. After analysis the information through the descriptive statistics shows the positive impact of the KHS-II project for the local people. Like same, the overall statistics of the regression model result is significant in the5% degree of freedom indicate that the project has positive economic impact for the likelihood of the surrounding community people. The research concluded that KHS-II project have positive impact on the likelihood situation to the surrounding community people.
Subordination in Western Tamang
Authors: Adhikari Manju
Published: February 2023

This article examines the clause combining in Western Tamang of Nuwakot district in Nepal. The significance of language as spoken in a particular community of Nepal reflects in the diversity as being accommodated in the national policy of language by the language commission of Nepal. Western Tamang is a major dialect of Tamang, a Tibeto-Burman language spoken in Nepal. The main goal of this study has been to analyze the forms and functions of clause combining in Western Tamang. This article describes the process of clause combining from both formal and functional perspectives. The data for this study have been taken from the Western Tamang dialect spoken in Rasuwa and Trishuli based on functional-typological grammar of T. Givón (2001).However; simple clauses are discussed in terms of subordination and coordination to some extent. Subordination involves five kinds of clauses: serial verb construction, complement clauses, adverbial clauses, relative clauses and converbal clauses. In subordination, Western Tamang uses non-finite form of the verb as a major strategy for clause combining. In coordination, except for conjunction and adversative conjunction, it uses coordinators borrowed from Nepali. It uses simple juxtaposition, an asyndeton coordination for conjunction. Clause combining as a morpho-syntactic phenomenon in Western Tamang reveals typologically interesting characteristics which needs from a broad typological perspective. The morpho-syntactic analysis of clause combining in the Western Tamang would contribute to understanding new phenomenon in Western Tamang and other related languages. This study may provide the basic foundation for the further study of the morpho-syntactic aspects in dialect. It is useful to local community for preparing materials for multilingual education in the dialect as well. Despite differences perceived among the Tamang speaking people in terms of language variations, the basics in their language are similar. The beauty and property of language can be seen in diversity.
Compulsory Basic Education and Social Inequality: State of Local Government and Compulsory and Free Education Act 2075 BS
Authors: K.C. Ram Bahadur
Published: February 2023

This article analyses the constitutional and legal provisions for school education and particularly Compulsory and Free Education Act, 2075 of Nepal. These provisions are oriented toward creating an environment where all citizens can get basic education so as to enhance equal and just Society. Compulsory and Free Education Act, 2075 is enacted to implement the constitutionally Assured fundamental right to education, and provision of free and compulsory school education without evidence-based analysis, planning and budgeting. The provisions of Compulsory and Free Education Act, 2075,in essence, are closed to the imposed social order from the top envisioned by Durkheim, influence and control of the powerful section of the society by Weber and inequality in the society due to unequal access to education by the classical Marxists.
Transfer matrix algorithm: Energy eigenvalue calculation of an arbitrary potential profile
Authors: Mishra Ravindra
Published: February 2023

The main objective of this article is to study transfer matrix algorithm, energy eigenvalue calculation. This article gives the idea that, in quantum mechanics, the transfer matrix algorithmic a method for calculating the energy eigenvalues of an arbitrary potential profile. The algorithm is based on the transfer formalism, which expresses the wave function of a particle in a potential as a product of matrices. The transfer matrix algorithm is particularly well suited for potentials that are piecewise constant, such as the potentials often used in quantum dot and quantum well devices. The transfer matrix algorithm begins with the construction of the transfer.