bluuebunny/crossref_metadata_2025 huggingface dataset:
Ensino religioso: política, diversidade, fenômeno religioso e práticas pedagógicas
Authors: Carneiro Everton
Published: February 2022

Everton Nery Carneiro nos apresenta um vasto conteúdo sobre religião, diversidade, fenômeno religioso e suas práticas pedagógicas. Essas temáticas convidam o leitor a se posicionar e se implicar com esse mundo religioso, experienciado de forma intolerante e agressiva que exclui e demoniza aqueles que não se afirmam e se firmam como cristãos. Às vezes, é preciso professar uma fé religiosa para ser aceito(a) e respeitado(a), e quando isso não acontece, a conduta religiosa do estudante ou colega é excluída, negada, demonizada e estigmatizada. Partindo dessa constatação do cenário educacional, o autor propõe nesta obra uma prática pedagógica inclusiva com adesão dos estudantes e professores no sentido de buscar juntos a construção de um projeto pedagógico que tenha como princípio educativo a ética, inclusão, diversidade religiosa e humana. Isso exige uma nova postura pedagógica humanizada nos espaços pedagógicos e um engajamento respeitoso dos atores que compõem a escola e buscam construir uma pedagogia freireana. Assim sendo, a obra Ensino religioso: política, diversidade, fenômeno religioso e práticas pedagógicas nos convida a pensar e engajar em uma perspectiva de educação que inclui, humaniza, compartilha saberes e produz conhecimentos necessários à transformação social, educacional e política de cada sujeito. Em suma, o autor mostra para nós, leitores, que é possível construir uma pedagogia com base na discussão dos valores religiosos e não religiosos dos estudantes, com ênfase à formação humana e o reconhecimento dos valores sociais, culturais das tradições religiosas dos sujeitos, atores dos espaços escolares e da sociedade.
Enseñanza-aprendizaje de la electrónica digital basa- do en niveles de complejidad de programación
Authors: Jiménez Hernández Luis Alexánder , Laiton Poveda Ignacio
Published: February 2022

En este artículo se presentan los aspectos principales del proyecto “Etapa de análisis de aprendizajes en estu- diantes empleando el prototipo para procesos de enseñanza-aprendizaje de la electrónica digital con dispositi- vos programables en la especialidad técnica mecatrónica”, financiado por la Escuela Tecnológica Instituto Técni- co Central (Conv. 04, 2016). Abarca la formulación y aplicación de una interacción didáctica, con el propósito de evaluar los avances en el aprendizaje de las temáticas relacionadas con la Electrónica Digital. Como resultados de investigación, se espera obtener información relevante acerca de los aprendizajes de los estudiantes de Elec- trónica Digital basada en la metodología didáctica formulada para el desarrollo del curso y apoyada en el uso del prototipo diseñado en la etapa previa a este proyecto.
The use of spatial statistics in the analysis of salaries at poviat level in Poland
Authors: Ręklewski Marek
Published: February 2022

The spatial differentiation of salaries is the subject of many scientific studies, both theoretical and empirical. One of the factors determining remuneration in Poland is the structure and type of business activity, specific for a given region and depending on its poviats (counties) in terms of the level of the average gross monthly salary by means of spatial autocorrelation statistical methods. The analysed statistical data for 2010–2019 come from the Local Data Bank (Bank Danych Lokalnych – BDL) of Statistics Poland. Global and local measures were used in the analysis. The calculation of the global parameters of spatial autocorrelation was based on the I Moran and C Geary statistics, while the Ii Moran statistic, which belongs to local spatial indicators from the LISA group (Local Indicators of Spatial Association), was used to identify the local autocorrelation. The statistical significance of the global statistics was verified by means of a randomisation approach based on theoretical moments.
The I Moran and C Geary global statistics indicated a significant (very weak or weak) and positive spatial autocorrelation between poviats in terms of the level of average gross monthly salaries in 2010–2019, which shows the existence of spatial poviat structures of similar values, i.e. clusters with high or low values of average salaries. The increase in I Moran’s statistics and the growth of the C Geary in the analysed period indicate a decrease in the differentiation of average monthly salaries between poviats, thus signifying an increase in the dependence of spatial autocorrelation. The analysis of the results of the obtained local statistics allowed the determination of clusters of similar poviats in Poland, e.g. Mazowiecki, Pomorski and Śląski. Furthermore, the results of the analysis indicated the presence of outlier poviats.
Maria Grzegorzewska's doctoral dissertation in the context of the development of psychological sciences at that time and some aspects of her biography
Authors: Hryniewicka Anna
Published: February 2022

This article is an introduction to Maria Grzegorzewska's doctoral dissertation on the development of aesthetic feelings in children and adolescents. It presents the course of her education at the International Pedological Faculty in Brussels and the Sorbonne in Paris, the value of her doctoral dissertation in the context of the development of psychology at that time, and the circumstances surrounding the change in her interests and life plans, which led to the creation of an original concept of teacher education and the establishment of the National Institute of Special Education.
Blessed Mother Elżbieta Róża Czacka: an outstanding typhlopedagogue
Authors: Kuczyńska-Kwapisz Jadwiga
Published: February 2022

On September 12, 2021, Mother Elżbieta Róża Czacka was proclaimed Blessed. It is an opportunity to recall the events of her life and activity as well as her achievements in the field of typhlological theory and practice. We know Róża Czacka's views on the upbringing, education and rehabilitation of the blind and visually impaired mainly thanks to specialist publications in pedagogical journals: "Szkoła Specjalna" (System Braille’a w Polsce [Braille System in Poland] and Książka niewidomego [Book of the Blind]) and „Ku szczytom” (Dziecko niewidome) [Blind Child]. The article pays particular attention to her research efforts to adapt the Braille system to the Polish alphabet, as well as to the topicality and great importance of her theses in the context of contemporary expectations. Both Róża Czacka and the environment she created and shaped enjoy unflagging recognition and social prestige.
Contralateral and Lateral Views: Analysis of the Technical Aspects of Spinal Cord Stimulator Lead Insertion
Authors: Gill Jatinder , Kohan Lynn , Hasoon Jamal , Urits Ivan , Viswanath Omar , Sadegi Kambiz , Orhurhu Vwaire , Lee Anthony C , Aner Musa M , Simopoulos Thomas T.
Published: February 2022

Background: Spinal cord stimulation (SCS) is an established treatment modality for neuropathic pain. The critical part of this technique is safe access to the epidural space for lead placement. There have been innovations in radiological views, improving access to the epidural space. Objectives: This study analyzes the adoption of these technical advantages in daily practice Methods: We conducted a survey of members in the Spine Intervention Society and American Society of Regional Anesthesia in regard to the practice patterns in SCS therapy. Here we present our findings regarding the use of contralateral oblique (CLO) and lateral views as well direct upper thoracic or cervicothoracic access for SCS lead insertion Results: A total of 195 unique responses were received between March 20, 2020 and June 26, 2020. Forty-five percent of respondents “always used” the lateral view technique while 15% “always used” CLO view for SCS lead insertion. Overall, sixty-five percent of respondents used the CLO view with varying frequency. Cervical and upper thoracic approach for cervical SCS lead placement is always or often used by 66.8% of the respondents. Conclusions: A depth view (CLO or lateral) is always used by only 45 - 60% of the respondents and CLO view has been rapidly adopted in clinical practice for SCS lead insertion. Direct cervicothoracic and upper thoracic is the preferred approach for cervical lead placement by the majority.
Falsedad en las primeras obras de Agustín
Authors: Sato Makiko , Eguiarte B. Enrique A. ,   Order of Augustinian Recollects
Published: February 2022

In the second book of Soliloquia, Augustine queries: what is ‘true’ and what is ‘false’. Through the examination, Augustine (Ratio) expresses the idea that ‘true’ is that which exists. Therefore, whatever exists is true; nothing will be false. But then, what is ‘false’? This paper will first clarify that the examination of ‘false’ in Soliloquia relates to Augustine’s awareness of the problem of sin. Already in Soliloquia, Augustine finds that the soul can have in itself the cause of sin so as to be unable to have the truth. Secondly, the author examines how the epistemology of falsehood is developed in the early Augustine by examining his articles after Soliloquia, focusing on the concept of lying in De Genesi contra Manichaeos and De vera religione. This will show that Augustine's understanding of falsehood and lying is related to his soteriology. Thirdly, the paper focuses on q. 63 of De diversis quaestionibus LXXXIII, in order to clarify what Augustine thinks about the relationship between God and human soul, where Augustine notes the significance of knowing and confessing sin as the means of cooperative salvation already described in his early works.
Teaching Medical Ethics through Medical Law
Authors: Cowley Christopher ,   Philosophy Documentation Center
Published: February 2022

Medical ethics is normally taught in a combination of three ways: through discussions of normative theories and principles; through for-and-against debating of topics; or through case studies (narrative ethics). I want to argue that a fourth approach might be better, and should be used more: teaching medical ethics through medical law. Medical law is already deeply imbued with ethical concepts, principles and reasons, and allows the discussion of ethics through the “back door,” as it were. The two greatest advantages of the law are (i) its familiar authority, especially among the disengaged medical students who have little interest or respect for the subject of ethics; and (ii) its focus on the reality of the people and the tragedies discussed (as opposed to the abstractness of a lot of ethical discussion). Finally, I argue that medical law, unlike ethics, allows more efficient and more detailed MCQ assessment.
Effect of Yb: Fiber laser on surface roughness and wettability of titanium
Authors: Dündar Yılmaz , Halil Tepe , Nigiz Remzi , Seyfioğlu Polat , Mutluay Unal
Published: February 2022

Background/Aim: In recent years, the role of computer aided design (CAD) and computer aided manufacturing (CAM) in dentistry has increasingly become important. However, the influence of different Yb: fiber laser applications on surface roughness of CAD/CAM implant has rarely been studied. The aim of this study is to investigate the effect of different Yb: fiber laser parameters on the surface roughness of CAD/CAM titanium. Material and Methods: Titanium samples, produced by CAD/CAM, were divided into 11 groups according to laser parameters such as scanning types (ST), application angles (AA) and hatch interval (HI). The surface roughness of CAD/CAM titanium was examined for each group. Wettability contact angles (CA) were also determined. Results: The highest surface roughness (43 mm) value was obtained for Group 10 (three-ways ST, 60o AA, 0.07mm HI). The lowest value (2.77 mm) after control group was obtained for Group 6. Surface roughness values, for Group 3, Group 9 and Group 10 were significantly higher than for the other groups (P= 0.000). In contact angle evaluations, the highest contact angle (144o) was observed in Group 10, while the lowest (95o) was observed in control group. Conclusions: Surface roughness was dependent on mixed effect of the laser application parameters. Three-ways ST, 60o AA, 0.07mm HI provided highest surface roughness and wettability contact angles. The surface roughness values of one-way ST, 0.06 mm HI, two-ways HT, 45o AA and 0.08 mm HI and three-ways ST, 60o AA and 0.07 mm HI were significantly higher than for the other groups (P=0.000).
Submandibular swelling, pulsations and otalgia due to sublingual gland and blood vessels herniation through mylohyoid boutonnière: Case report
Authors: Janović Aleksa , Bracanović Đurđa , Antić Svetlana , Marković-Vasiljković Biljana
Published: February 2022

Background/Aim: Mylohyoid boutonnière is a common anatomical variant with extremely rare clinical manifestations. We report two cases of symptomatic unilateral mylohyoid boutonnière with sublingual gland herniation. Case report: The first was a 34-year-old female with a two months history of a left submandibular swelling, intermittent pulsations, and otalgia. The second 67-year-old female presented with a left submandibular pain six months after total thyroidectomy due to papillary carcinoma. After detailed clinical and radiological evaluation by ultrasonography (US) and computed tomography (CT), the mylohyoid gap with sublingual gland herniation was diagnosed in both patients. The dynamic US with a tongue pressed down on the mouth floor revealed blood vessel compression by a herniated sublingual gland in the first patient. Conclusions: This is the first case of a mylohyoid boutonnière related intermittent vascular compression. Dynamic US and CT may help to differentiate intermittent and persistent sublingual gland herniation through the mylohyoid boutonnière from other pathological lesions in the submandibular region.
Role of PKCd and ERK1/2 in trombin-stimulated vascular smooth muscle cells proliferation
Authors: Smiljanić K. , Resanović I. , Savić K. , Obradović M. , Putniković B. , Đorđević J. , Isenović E.R.
Published: February 2022

Cardiovascular disease is the greatestest single cause of mortality and its major underlying pathology is atherosclerosis. The proliferation of vascular smooth muscle cells (VSMC) is a key event in the pathogenesis of various vascular diseases, including atherosclerosis and hypertension. Thrombin is involved in the differentiation and abnormal proliferation of VSMC associated with atherosclerosis and hypertension. Thrombin stimulation results in extracellular signal-regulated kinase (ERK1/2) activation through transactivation of the epidermal growth factor receptor (EGFR). Based on our reacent studies in which PD98059 used to inhibit ERK1/2, we have shown previously that ERK1/2 was involved in the regulation by thrombin of VSMC's proliferation. In addition, protein kinase C delta (PKCd) have also been detected in VSMC and shown to be regulated by thrombin. In this review, we are presenting literature data relating to role of PKCd and ERK1/2 in mediating the mitogenic action of thrombin in VSMC.
Public health and biomedical aspects of scoliosis among school population at the age of 7-14 in the Republic of Macedonia
Authors: Antuleska-Belčeska G.
Published: February 2022

Introduction: Scoliosis is a three-dimensional deformity of the spine, which as a pathological condition was known and treated at the time of Hypocrites. Scoliosis is a problem which exists in all countries around the world, especially in the developing ones. In RM, scoliosis among school children at the age of 7-14 is represented by 7.5 %. Objective: To certify the representation of radiologically diagnosed scoliosis among school children in RM, the specific types of scoliosis in relation to age, location, degree of scoliosis according to the angle of deviation of the spine, as well as to define the risk factors for the occurrence. Study Design: Casecontrol study from casual type conducted on children at the age of 7-14. Methods: In order to fulfil the purposes of the research, two groups were formed: examined and control group. Children were divided into three groups according to age: the age of 7-9, 10-12 and 13-14. A questionnaire was also prepared on the basis of recommendations given by SRS. The questionnaire consisted of 15 rules and was intended for parents. Statistical processing was done in Statistics for Windows 8.0. Results: According to gender distribution, scoliosis is more likely to be found in females, 64.49% in comparison to male children. Distribution according to age illustrates that scoliosis is most likely to appear among age groups of 10-12, 58.7%. Juvenile and adolescent scoliosis is much more likely to appear in female children. The connection between the socioeconomical status and scoliosis was also confirmed. Namely, 52.9% of children from average socioeconomical status according to FAS-scale have 2.18 times significantly greater risk of developing scoliosis. Ratio of scoliosis according to the place of living (urban and rural area) is 52.9% : 47.1%. Sitting in front of the computer, physical inactivity, as well as high BMI is a great risk factor for development of scoliosis. The questionnaire also confirmed low level of education among parents regarding this problem, 15.9%. Symmetrical sports prevent scoliosis from developing. Within the examined group of children, the division is made according to the level of scoliosis: mild, medium and severe scoliosis. Most often developed is the double scoliosis 66.87% in comparison to single thoracic 12.32% and lumbar 21.02% deviation. The angle of deviation (Cobb) moves in intervals of 9-78 degrees, with average value of 15.76+8.5. Conclusion: The first research of this type in the country, which gives information of essential significance for improvement and promotion of health, as well as improvement of primary prevention, all aiming to protect child health, and thus creating a healthy society and realization of the Declaration of WHO "Health for everyone in the 21st century".
Students attitudes on learning English for medical academic purposes and adapting the teaching process to their needs
Authors: Mićić S. , Sinadinović D.
Published: February 2022

Since the Faculty of Medicine, University of Belgrade is the institution of long-term tradition of the study and teaching of EMP, the aim of this paper is to investigate the attitudes of students towards these teaching programmes and the teaching material in order to adapt them to the students' real needs. Two questionnaires were used in the research and they were completed by 128 first and second year students of the integrated academic studies and 9 students of the English studies. These questionnaires consisted of open and close questions (the first research) and evaluating statements on Likerttype scale (the second research). The results we got in this small-scale research show that the students are aware of the need to learn this specialized language, that they consider it difficult to master as related to General English (GE), as well as what in their classes they find useful or useless for learning English for Medical Purposes and if they would change anything to their actual needs. As for the teaching material used in classes, the opinions of the limited number of surveyed students are mostly very positive, but a larger-scale research should be conducted to get more relevant results.
Increase of Healthy Food Quality among the Kazakhstan Population
Authors: Z. Yessimsiitova  , N. Ablaikhanova  , S. Sagyndykova  , G. Tussupbekova  , M. Kulbayeva  , G. Atanbayeva  , M. Aitzhan    , Z. Bissenbayeva
Published: February 2022

At present, one of the most important urgent issues is the study of healthy nutrition of the population of Kazakhstan. Proper nutrition ensures the growth and development of children, contributes to the prevention of diseases, increase the capacity for work and prolong the life of people, while creating conditions for adequate adaptation to the environment.Most of the population of Kazakhstan because of technological processing, the use of inadequate food raw materials, influence of other causes, does not receive the necessary amount of essential components of food, which lead to illnesses, premature aging and shortening of life.The situation aggravates by the low cultural level of the population in matters of rational nutrition and the lack of skills for healthy lifestyles.In this regard, the main task in the work was to study methods of improving the health and quality of life of the population of Kazakhstan, especially those living in zones of environmental problems and contacting with harmful factors.
Et in Arcadia ego: Elegias da pátria e da infância na poesia de Alberto de Lacerda e Rui Knopfli
Authors: Pereira Paulo Alexandre
Published: February 2022

Conformadas por circunstâncias biográficas e eixos temáticos comuns, as poéticas de Rui Knopfli (1932-1997) e Alberto de Lacerda (1928-2007) exploram um mesmo ethos elegíaco, compaginando-o com a tópica evocação nostálgica dos lugares da memória. Tanto no caso do autor de Elegias de Londres, como no de O Monhé das Cobras, o género da elegia surge coligado com o tema seminal do exílio, que em ambos surge declinado nas suas múltiplas modulações geográficas, políticas, temporais e ontológicas, com particular incidência nas saudades da infância moçambicana comum aos dois poetas. Se, no caso de Knopfli, a elegia tematiza a dilacerante experiência de expatriado de um império extinto, num verdadeiro trabalho de luto pós-colonial, em Lacerda a exaltação libertária vivida numa pátria adotiva, livre da sombra da ditadura, não deixa, contudo, de ser manchada pela solidão congénita de quem se sabe exilado de si próprio. Mais do que a convencional meditatio mortis que ecoa na elegia clássica, na poesia de Knopfli e Lacerda reverbera-se, assim, a consciência de que qualquer arcádia é precária e que, mais cedo ou mais tarde, nela se insinuará o seu fim.
Violência, Samurais e o Bushido no cinema de Akira Kurosawa
Authors: Figueiredo Antônio Marcus Lima
Published: February 2022

O livro trata do uso da violência encenada no cinema como recurso narrativo, expressivo e discursivo. Tomando as cenas de luta como locais privilegiados para examinar a relação entre cultura e cinema, a obra examina como a violência encenada significa nas obras do diretor japonês e como esse processo faz dialogar tradições cinematográficas orientais e ocidentais, com a cultura marcial propagada pela figura do samurai e por seu código de honra, o bushido, importantes elementos do nacionalismo japonês.
Measurement of local contact potential difference of atomic scale Au/Si(111)-(7×7) delocalized adsorption state in room-temperature and ultra-high vacuum environment
Authors: Wang Hui-Yun , Feng Jie , Wang Xu-Dong , Wen Yang , Wei Jiu-Yan , Wen Huan-Fei , Shi Yun-Bo , Ma Zong-Min , Li Yan-Jun , Liu Jun ,   State Key Laboratory of Dynamic Measurement Technology, North University of China, Taiyuan 030051, China,   School of Instrument and Electronics, North University of China, Taiyuan 030051, China,   Shanxi Province Key Laboratory of Quantum Sensing and Precision Measurement, North University of China, Taiyuan 030051, China,   Department of Applied Physics, Graduate School of Engineering, Osaka University, Osaka 5650871, Japan
Published: February 2022

The structural properties and local contact potential difference of Au on Si(111)-(7×7) surface are studied by the homemade ultra-high vacuum non-contact Kelvin probe force microscope. Although scanning tunneling microscopy has been widely used to study the metal- adsorbed semiconductor surfaces on an atomic scale, the tunnel current measured by scanning tunneling microscopy is easy to lead the charge states to accidentally switch in the measurement process, and it is limited only to the observation of metal and semiconductor surfaces. Kelvin probe force microscope allows us to directly measure the charges at different positions of various flat surfaces by local contact potential difference on an atomic scale, which has become a more convenient and accurate means of charge characterization. In this paper, the topography and local contact potential difference of Au adsorbed Si(111)-(7×7) surface are measured on an atomic scale by Kelvin probe force microscope at room temperature, and the corresponding adsorption model and first principle calculation are established. The differential charge density distribution of the stable adsorption position of Au/Si(111)-(7×7) is obtained, and the local contact potential energy difference relationship of the stable adsorption position of Au on Si surface is given, The mechanism of charge transfer between Au atom and Si(111)-(7×7) surface during adsorption is analyzed. The experimental results show that at room temperature, single Au atom will form triangular delocalized adsorption state in the half unit cell of Si(111)-(7×7). The delocalized adsorption state is due to the fact that the moving speed of a single Au atom in the HUC is faster than the scanning speed of Kelvin probe force microscope, and the local contact potential difference measurement of Au/Si(111)-(7×7) adsorbed surface can effectively identify Au and Si atoms. Obviously, this research is of great significance in promoting the development of surface charge precision measurement, and is expected to provide some insights into the charge properties of metal adsorbed semiconductor surfaces.
Efficacy of brain natriuretic peptide vs. nicorandil in preventing contrast-induced nephropathy: a network meta-analysis
Authors: Mei Ziwei , Luo Songmei , Chen Peipei , Zhang Qiankun , Zhou Limei , Zhu Chaoyong , Zhu Hong , Jin Lie
Published: February 2022

This study aimed to conduct a network meta-analysis (NMA) to compare the efficacy of brain natriuretic peptide (BNP) vs nicorandil for preventing contrast-induced nephropathy (CIN). Databases of Pubmed, Cochrane, Embase, Web of Science were searched by keywords for eligible studies of randomized controlled trials investigating different agents (BNP, nicorandil, nitroglycerin, intravenous saline) for preventing CIN. The outcomes included a change in serum creatinine level at 48 h and the incidence of CIN after percutaneous coronary intervention (PCI) or coronary angiography (CAG). A total of 13 studies with 3,462 patients were included. Compared with intravenous saline alone, except for nitroglycerin (odds ratio [OR]: 1.02, 95% CI [0.36–2.88]), the other drugs significantly reduced the CIN incidence with OR of 0.35 (95% CI [0.24–0.51]) for BNP, 0.52 (0.29, 0.94) for usual-dose nicorandil, 0.28 (0.19, 0.43) for double-dose nicorandil. BNP and double-dose nicorandil significantly decreased the change of serum creatinine (SCr) levels with mean difference (MD) of −6.98, (−10.01, −3.95) for BNP, −8.78, (−11.63, −5.93) for double-dose nicorandil. No significant differences were observed in the change of SCr levels for nitroglycerin (−4.97, [−11.46, 1.52]) and usual-dose nicorandil (−2.32, [−5.52, 0.89]) compared with intravenous saline alone. For double-dose nicorandil, the CIN incidence and the change of SCr level in group of 4–5 days treatment course were more than group of less than or equal to 24 h treatment course (OR of 1.48, [0.63–3.46] and MD of 2.48, [−1.96, 6.91]). In conclusion, BNP and double-dose nicorandil can have effects on preventing the incidence of CIN and double-dose nicorandil performed better than BNP. In double-dose nicorandil groups, a course of less than or equal to 24 h before and after procedure performed with better efficacy than a course of 4–5 days.
Synthesis and Significance of Atrial Natriuretic Peptide: A Review
Authors: Jasmeen Shaikh , Annabelle Rajaseharan , Pradeep Bokariya , Shirin Shaikh
Published: February 2022

Unhealthy lifestyle habits lead to numerous diseases and among them heart diseases are predominant. Various factors play important role in heart diseases. Amongst such factors is Atrial Natriuretic Peptide (ANP) which tends to be significant. Though the discovery of ANP is the recent one, but its role in diagnosis of cardiovascular disease has taken fasttrack. In this context, authors have tried to review and summarise the current evidences and roles of ANP in cardiovascular diseases along with the focus on rising use of ANP in diagnosis and treatment of cardiovascular diseases. Hence, this is a brief account of discovery and biological actions of ANP, its synthesis and role as a biomarker
An Extremely Rare Case of Granular Cell Tumour of Right Nasal Vestibule
Authors: Agarwal Pooja , Kaushik Nupur , Kumar Lalit , Singh Akhil Pratap
Published: February 2022

Granular Cell Tumour (GCT) of nasal and paranasal area is an extremely rare entity, while the most common site is the tongue in oral cavity. GCT was first time described by Abrikossoff in 1926, which occurs in 3rd to 5th decades of life and most frequently involving the head and neck region. Abrikossoff in 1926, first time described GCT, to be derived from smooth muscle and gave the term myoblastomas, also known as Abrikossoff’s tumours. Schwann cell origin of GCT was demonstrated on immunohistochemistry through positive S100 protein identification. Herein, the authors report a case of GCT arising from right nasal vestibule in a 28- year-old female who presented with swelling since three months. On gross examination, the specimen revealed firm red and white pieces of tissue measuring 0.8x0.8x0.5cm. Diagnosis was made by histopathological examination which was confirmed by PAS special stain and S100 immunohistochemistry. Author also abridge the clinical information, microscopic features, treatment and patient status after follow-up. This case is believed to be the 7th reported case of GCT as primary lesion at this location.
Production and Management Practices of Goat Farming in Sirohi District, India
Authors: Kakraliya Arjun Lal , Pandey Ramesh , Tetarwal Jhabar Mal , Chopra Goutam , Serawat Rohan
Published: February 2022

Total 80 respondents  from Sirohi tehsil of Sirohi  district  from 4 randomly  selected villages were used for this study. Total 80 respondents were used in this study. The results indicated  that  most  of goat  owners  took  extra  care  at the time  of kidding  (75.00%)  and pregnant doe (81.25%). 55.00 per cent respondents used 20 -40 breedable  goat per breeding buck for service. Results showed that 60.00 per cent goat owners gave extra ration to buck during breeding season. 40.00 per cent respondents change the breeding buck every year to avoid  inbreeding and 47.50 per cent goat owners bred  the goat during rainy season and half of goat  owners  selected  the breeding  buck  on the basis  of body  weight.  Majority  of goat owners practiced  semi  stall-feeding  (60.00%),  4 -6 hours grazing  (40.00%)  and grazing  on community type pasture land (56.25%). All goat owners protected the pasture land. Balance ration was feed by 37.50 per cent and 62.50 per cent did not know regarding balance feeding. Majority of respondents  offered green fodder feeding (65.00%), looping of trees (93.75%), feeding  dry  fodder  (68.75%),  out  of them  result  showed  that  36.25  per  cent  feeding  of concentrate  and 63.75  per cent did not know regarding  feeding  of concentrate,  give extra ration to kids for meat purpose (65.00%). Data showed that feeding of pregnancy ration for pregnant  animal  (32.50%),  feeding  of mineral  mixture  (77.50%),  feeding  of common  salt (45.00%) and most of goat owners were used clean water for drinking purpose (93.75%).
Socio-economic Empowerment of Women through Self Help Groups: An Empirical Study in Odisha, India
Authors: Hossain Sk. Mosharaf , Mishra Subhasree , Atibudhi H. N.
Published: February 2022

The past three decades have witnessed tremendous emphasis and policy support to the collectivization of women into self-help groups (SHG) for their socio-economic empowerment; consequently, there is a surge in the numbers of the SHGs in the country. The present study was undertaken in Khordha district of Odisha with 80 SHG women to reflect on the impact of being in SHG on incremental employment, income, expenditure, and savings. It also assessed how the decision-making ability of SHG members is influenced by different determinants. The constraints that challenge SHG were also evaluated. The majority of SHG members were able to get additional employment under different activities by SHG finance. All the members (100%) reported increased income after they join the SHGs. Gini ratio-a measurement of inequality has shown improvement from 0.489 to 0.154 after the women joined an SHG. An upward shift in expenditure has been observed as 85% of women after joining SHG expend more than INR 2000 compared to just 11.25% before they were part of the group. Before SHG inclusion, only 25% of women used to save INR 100 or more a month but post participation in SHG, 85.25% of members reported to have saved more than INR 100 every month. However even after joining SHG, both household and financial decision-making capacity is largely determined by education level of the women, age, the number is working days. Challenges in marketing products, competitive market environment, inadequate financial services, and lesser scope of business skilling opportunities are the major challenges, the SHGs face very often. A target-specific and well-directed supports from the government will act as an enabler for the sustainable growth of this SHG initiative.
Spatiotemporal Modelling of Endemic-epidemic Cholera in Nigeria
Authors: Usman A. , Isah A. , Abubakar U. , James M.
Published: February 2022

This study used a multivariate negative binomial model to capture the Spatiotemporal endemic-epidemic of infectious disease and explore the spatial and temporal patterns of cholera outbreaks in Nigeria. The model for the epidemic part measured spatial weights for the disease spread across the geographical neighboring regions and the endemic part accounted for temporal variation of disease incidence. Weekly count data on cholera from the Nigeria Department of Disease Control and Monitoring Epidemiology (NCDC SED) between January 1st and November 19th, 2018 was used to illustrate the model. In fitting the model, the study has shown that the model with seasonality and autoregressive components provided an adequate fit for the cholera count data and also perform better than the model without seasonality and autoregression for modelling the Spatiotemporal dependency structure of cholera disease
Abscisic Acid Mediated Abiotic Stress Tolerance in Plants
Authors: Rehman Rao Saad , Ali Mujahid , Ali Zafar Syed , Hussain Mubashar , Pasha Asad , Saqib Naveed Muhammad , Ahmad Muhammad , Waseem Muhammad
Published: February 2022

Abiotic stress is one of the major environmental stresses that decrease crop growth and yield even in irrigated soils worldwide. An important plant hormone abscisic acid (ABA) plays a vital role in addressing various stresses, such as thermal or heat stress, high salinity level, heavy metal stress, low temperature, drought, and stress on radiation. Its role is well explained in different processes for development, including germination of seed, stomata closure, and dormancy. Abscisic acid works through alteration of the gene expression levels and subsequently analyzing the cis and trans-regulatory components for receptive promoters. It is considered to have an interaction with the signaling elements of processes taking part in stress response and seed development. In general, a plant can be vulnerable or tolerant to stress when the correlated actions of different stress-reacting genes are considered. Many transcription factors are required for the regulation of expression of abscisic acid-responsive genes through interacting with their specific cis-acting components. Therefore, the mechanism behind it should be understood to make the plants stress-tolerant. This review explains the significance and function of ABA signaling concerning specific stress, the management of abscisic acid biosynthesis, and transcription factors (TFs) associated with stress tolerance.
Quantification of Negative Externalities of Irrigation Well Investment of Overexploited Firka: The Case of Coimbatore District of Tamil Nadu
Authors: Deepika K. , Kumar D. Suresh , Ashok K. R. , Kannan Balaji , Duraisamy M. R.
Published: February 2022

Aims: To study the total negative externality cost of irrigation well investment of overexploited firka.

Study Design: Purposive random sampling.

Place and Duration of Study: The study was conducted in the Coimbatore district of Tamil Nadu and the survey was conducted during July 2021 and September 2021.

Methodology: The sample size selected for the study is 160 which includes farmers (80 farmers+80 farmers) from Annur and Thondamuthur firka. Four villages were selected from each firka, similarly, 20 farmers from each village were selected for the study. Market price method and damage cost method were used to estimate the externality cost of overexploited firka of Coimbatore.

Results: The total negative externality cost estimated from the analysis is Rs. 21.19 lakhs per hectare of gross cropped area (GCA). The damage cost of dried wells is dominant when compared to all other costs. The cost of increased pumping hours is very negligible.

Conclusion: Small and marginal farmers are highly affected among different the category of farmers. The externalities can be reduced by optimal extraction of groundwater which can be achieved by monitoring done by the formal and informal institutions.
Projection of Investment and Incremental Capital Output Ratio Analysis of Nusa Tenggara Barat Province
Authors: . Zulkieflimansyah , Nurjihadi Muhammad , Ilman Abdul Hadi , Kemala Sari Putri Reno , Masniadi Rudi , Hasri Diah Anggeraini
Published: February 2022

Aims: This study aims to project investment in the Province of NTB.

Study design: This research is a quantitative research using secondary data for analysis. Place and Duration of study: West Nusa Tenggara, Duration of study from September to December

Methodology: There are two analytical tools used, namely trend analysis to make investment projections based on the MAPE (Mean Absolute Percentage Error) and MAD (Mean Absolute Deviation) values. Furthermore, investment needs are analyzed using the Incremental Capital Output Ratio (ICOR).

Results: Based on the results of the study, it was found that the investment trend in NTB was using the exponential growth model. Based on ICOR analysis, the average ICOR value in 2011 – 2020 is 12, 11 with the assumption of a lag of 0, and reaches 8 with a grace period of 3 years. If it is assumed that the ICOR value of NTB has not changed, namely 8, then with economic growth of 7% as targeted in the RPJMD 2109-2023, an increase in investment of 56% is needed, even though if viewed from the average increase in investment, it was only 43% in 2016 – 2020.

Conclusion: The projection carried out in this study only uses trend analysis. In subsequent research, the use of other analysis tools to projections such as the use of dynamic systems and modeling can be done so that the projection of investment needs can be in accordance with the regional concert.
Optimizing Percentages of Asphalt Content Extracted from Mixes Containing RAP and/or RAS
Authors: Deef-Allah Eslam , Abdelrahman Magdy
Published: February 2022

Extracting asphalt binders (ABs) from mixes including recycled asphalt shingles and/or reclaimed asphalt pavement (RAP) needs more investigation. The most popular way for extracting ABs from mixes is centrifuge extraction. The fine materials (dust) extracted with the effluent were quantified using ashing and centrifuge mineral matter determination methods (MMDMs). MMDM could underestimate the extracted asphalt content (EAC)% by overestimating dust amounts. As a result, the actual asphalt content% values were compared to the EAC% values utilizing ashing and centrifuge MMDMs. The EAC% values using the centrifuge MMDM showed more accurate values when compared to the EAC% values using the ashing MMDM. The fabrication techniques used in the field, lab, and plant mixes and the additives used in these mixes altered the interaction processes between virgin asphalt binders (VABs) and RAP binders. More interactions occurred in the plant mixes due to reheating these mixes prior to compaction in the lab. Thus, the EAC% values from plant mixes were higher than the EAC% values from the same mixes obtained from the field. The interactions between the RAP binder and the VAB were boosted by Evoflex that increased the EAC% values.
A Review on Impact of Glyphosate on Development of Cancer
Authors: Prasad Monisha , Rekha U. Vidhya , Rajagopal Ponnulakshmi , Sekar Durairaj , Jayaraman Selvaraj
Published: February 2022

Pesticides are a vast mixture of compounds used to control pests like plants, moulds, and insects. In agriculture, non-agricultural vegetation management, and crop desiccant harvesting aid, chemicals from every major functional family of pesticides, such as insecticides, herbicides, fungicides, and fumigants, were frequently used. Herbicides are one of the most effective tools for farmers to obtain optimal crop yields when used correctly. Glyphosate (N-(phosphonomethyl) glycine) is a broad-spectrum weed killer that is used all over the world in agriculture and forestry. Glyphosate's herbicidal activity in plants is to disrupt the shikimic acid pathway's generation of branched-chain amino acids by preventing the binding of phosphoenolpyruvate (PEP) to the enzyme 5-enolpyruvylshikimate 3-phosphate synthase. This causes a deficiency in aromatic amino acid synthesis and, as a result, weeds mortality. Glyphosate exposure through food, drinking water, wind, water erosion, and other environmental pathways has been linked to human health issues as a carcinogen, mutagen, and reproductive toxicity. Glyphosate has a wide range of tumorigenic effects in biological systems, and epidemiological evidence suggests that glyphosate use on crops is linked to a wide range of cancers, including liver cancer, breast cancer, thyroid cancer, pancreatic cancer, kidney cancer, bladder cancer, and myeloid cancer. The shikimate pathway enzymes, intermediates, and derivative amino acids, which have been associated to genotoxicity and carcinogenicity, are thought to have a role in most cancer pathologies. This review summarises glyphosate's function in cancer pathology, including the ability of the glyphosate circuit to induce cancer and implications for future therapeutic methods.
Evaluation of the Antiurolithiatic Activity of the Extract of Boswellia serrata Roxb in Rats
Authors: Kushwaha Sujata , Tyagi Chandra Kishore
Published: February 2022

In rats' urinary bladders, the antiurolithiatic action of a methanolic extract of Boswellia serrata Roxb (root) was examined on the development of calculi on calcium oxalate crystal implants or zinc disc implants. The plant is a member of the Burseraceous family, and it has long been used as a folk remedy for urinary issues and stone removal. When a foreign body was present in the urinary bladder of adult rats, it caused urinary stones and smooth muscle hypertrophy. After 4 weeks after surgery, oral therapy with Boswellia serrata Roxb extract (0.25 and 0.5 g/kg per day) decreased calculi development but did not prevent smooth muscle growth. In the presence and absence of the extract (0.3–3 mg/ml) or atropine (0.3–3 nM), the contractile responses of isolated urinary bladder preparations to the muscarinic agonist bethanecol were not different among the experimental groups.
m-NUTRIC Score for Assessment of Nutritional Status and Treatment Outcomes in Chronic Kidney Disease Patients
Authors: Verma Prerna , Kumar Sunil , Acharya Sourya , Bawankule Shilpa , Wanjari A. K. , Agrawal Sachin , Bakre Anand
Published: February 2022

Background: Malnutrition entails insufficiency arising of protein, vitamin, and trace elements related to inadequate and unstable diet which may cause poor quality of life and sometimes even lead to death. Undernourishment is the leading reason having a greater impact on outcomes following treatment, which lengthens patient stay and impacts mortality and morbidity. Protein deficiency is commonly reported among chronic kidney disease (CKD) patients. Lack of proper nutrition affects the quality of life of patients with chronic kidney disease. Nutritional problems among CKD subjects needs to be detected earlier. This study aims to  assess the nutritional risk of patients with CKD by m-Nutric score and compare the  m-Nutric scores among patients with and without haemodialysis.

Materials and Methods: This will be a cross-sectional study in the Dept. of Medicine, at AVBRH, Wardha. Total 150 patients with CKD reporting to Medicine Department, AVBRH, Wardha  will be enrolled in the study. The m-NUTRIC score will be calculated as per the criteria. APACHE II at admittance and Sequential Organ Failure Assessment (SOFA) score will be assessed .  NUTRIC points will be calculated without interleukin (IL)-6. Morbidity data, duration of stay of patients and mortality will be recorded.

Expected Results: Subjects having m-NUTRIC scores more than or equal to five will be graded in the high risk category of undernourishment whereas scores less than  or equal to four will be categorised as low risk. We expect a significant correlation of m-NUTRIC scores ≥5 to duration of hospitalisation and risk of death.

Conclusion: The m-NUTRIC scores would be directly correlated with mean ICU duration of stay and mortality for patients with hospitalised CKD.
Virtual Screening to Identify Protein Targets of Aggregatibacter Actinomycetemcomitans Interacting with Emodin
Authors: Preety R. , Jeevitha M. , Priyadharsini J. Vijayashree , Jayaraman Selvaraj
Published: February 2022

Aim: The aim of the study is to identify protein targets of aggregatibacter actinomycetemcomitans interacting with emodin.

Introduction: Aggregatibacter mycetemcomitans is a gram negative bacteria that is associated with localized chronic periodontitis and other systemic diseases. The organism produces a number of virulence factors which provides some benefits to the bacterium. In this study, protein targets of Aggregatibacter actinomycetemcomitans interacting with emodin were identified.

Methodology: The present study follows an observational study design wherein we employed computational tools used to identify the targets, assess its functional role and virulence property. The protein targets in the bacteria were identified by virtual screening by using emodin as the compound.

Results: Peptide epitopes present in the virulence factors were identified using the BepiPred tool. The subcellular location of the protein targets were elucidated using emodin as the phytocompound. The 3 - Deoxy - D - manno octulosonic acid, ArcB, hypothetical protein and Arabinose - 5 - phosphate isomerase were found to be virulent.

Conclusion: Within the limits of this study, it provides substantial evidence on the protein targets acting against emodin.
Synthesis, Characterisation and Antimicrobial Evaluations of Acetyloxyphenyl-1,2,3-triazole Linked Hexahydro Acridinediones
Authors: Shanmugasundaram P. , Sujatha R. , Aanandhi M. Vijey , Manivannan V. , Sivaraju M.
Published: February 2022

10-(2-hydroxyphenyl)-hexahydro acridinediones were treated with chloroacetyl choloride to give 10-(2-chloroacetyloxyphenyl) hexahydro acridinediones, which were treated with NaN3 in acetone followed by reaction with DMAD yielded 10-[2-(1-triazolo-4,5-dicarboxymethyl)acetyloxyphenyl]-3,4,6,7,9,10-hexahydro-1,8-(2H,5H)-  acridinediones.
Evaluation of Haematological Parameters of Obese Individuals Based on Age Groups at Omisanjana Area of Ado Ekiti, Ekiti State
Authors: Obeagu Emmanuel Ifeanyi , Rashid Huba K. , Okafor Chukwuma J. , Omotunde Precious Ifeoluwa
Published: February 2022

Obesity is a chronic disease which has spread all over the world and threatens public global health. Eighty (80) obese individuals based on age groups. The table above show no significant difference in PCV (p=0.241), WBC (p=0.445), LYM (p=0.531), GRAN (p=0.514), MID (p=0.930), LYM (p=0.984), GRAN (p=0.682), MID (p=0.343), RBC (p=0.971), HGB, MCV (p=0.389), MCH (p=0.755), MCHC (p=0.052), RDW_CV (p=0.392), RDW_SD (p=0.177), PLT (p=0.055), MPV (p=0.224), PDW (p=0.432), P_LCR (p=0.096) when compared between obese individuals and non-obese individuals based on age group respectively.  Age group has no changes in the haematological parameters of obese individuals among the studied subjects.