bluuebunny/crossref_metadata_2025 huggingface dataset:
Quality of Education as a Factor of University Competitiveness
Authors:   Synergy University, Drondin Alexander L.
Published: December 2021

The strategic orientation of any modern educational organization is to achieve competitive advantages in the market of educational services. The competitiveness of the university is directly dependent on the quality of its educational services. Evaluation of the quality of education, in turn, goes to such concepts as the rating of the university and its accreditation. Discussion of this area of higher education is actively conducted in the academic community, but its research, especially in the realities of the digital economy, is insufficient, which makes this publication relevant. The purpose of the study is to identify the actual features of achieving high competitiveness in the conditions of digital transformation by a domestic university. To do this, it is necessary to analyze the existing experience of Russian higher education in terms of responding to the challenges of digital transformation and develop recommendations for achieving high quality education in modern conditions. The research methodology is based on the theoretical foundations of professional education and the competitiveness of Russian universities. The article analyzes the domestic and international experience in assessing the quality of education, while proving that the main criterion for assessing the competitiveness of a university is the quality of learning outcomes. Methods of comparative analysis, observation and generalization are used. The study proves that modern Russian higher education does not always adequately respond to the challenges and opportunities of digital transformation. A number of systemic problems hindering the achievement of high quality of modern higher education are identified. The necessity of combining the introduction of innovative technologies of the educational process with the preservation of the advantages of traditional education is confirmed. Promising directions of constructive interaction of the university with the most important stakeholders of higher education – employers are proposed.
Advertising Agency: the Specific Features of Working in a Competitive Digital Environment
Authors:   Synergy University, Deryabina Galina G. ,   Peoples’ Friendship University of Russia,   ROMART Contact LLC, Trubnikova Nina V. ,   Peoples’ Friendship University of Russia
Published: December 2021

The article is devoted to changes in the advertising market in the field of relationships between its main subjects. The author systematizes the problems that have intensified in connection with sanctions, restrictions and the global crisis caused by the global course of the pandemic 2020–2021. The research focuses on the advertising agency, its new role and functionality. Particular attention is paid to the agency’s work in the most dynamic segment of the advertising market – digital, and new tools, formats and technologies used in agency work. The study reveals a set of problems that arise in the digital environment and are associated, on the one hand, with man-made causes and features of information technologies 3.0, which are not so easy to adapt to solve marketing problems, and on the other hand, with the problems of communication management and updated agency functionality. Such a characteristic feature as transparency, which initially, at the dawn of the digital communication era, was a serious competitive advantage compared to classic advertising media, has now almost disappeared. This limits the possibilities for cooperation between advertisers, advertising distributors, and advertising producers. The movement towards transparency should be supported both at the macro-level of the industry and at the micro-scale of the individual agency, in order to help the agency business maintain its key role in the advertiser’s business and not push it to directly cooperate with advertising carriers, which will lead to a loss of content quality and media placement. In digital communications, the differentiation between the tasks of consistently strengthening the brand value and the tactics of quick advertising for immediate purchase is very serious, since these tasks are solved by completely different – not overlapping-tools. The authors consider integrated marketing in the digital environment as the implementation of the agency’s functions of planning, selecting promotion channels in accordance with the tasks set, budgeting, monitoring efficiency and building work with the subjects of the communication market.
From Competition to Competitive Cooperation: New Paradigm for Territories Development
Authors:   Institute of Economics of the Ural Branch of RAS, Vazhenina Irina S. , Vazhenin Sergey G. ,   Institute of Economics of the Ural Branch of RAS
Published: December 2021

The modern economic space demonstrates, on the one hand, the intensifying competitive struggle of various territorial entities for natural and financial resources, investments and business, for the population, qualified personnel, tourists, etc. On the other hand, the process of formation of competitive cooperation of territories, which does not exclude competition, and complements it, acting as a driving force for the development of the economy of regions and municipalities. The authors in the study assessed the current level and prospects of territorial competition, clarified the goals of competition of regions and municipalities. Consideration of the territory as a subject of competition is explained by the fact that the regions acquire the quality of a mega- enterprise. The potential of cooperation between the territories in the modern competitive economy is revealed. In modern Russia, competitive cooperation between territories is still very rare. A number of features of the evolution of competitive cooperation of territories are revealed: cooperation is specifically limited in time; any cooperation is inherent in risk; its formation and implementation always involve certain financial, intellectual, labor and other costs. The results of expert surveys conducted by the authors in 2007, 2010, 2013, 2016 and in 2019 made it possible to highlight positive and negative results, as well as the consequences of interregional and intermunicipal cooperation in a competitive economy. An assessment of the readiness of territories (regions, municipalities) for cooperation is given. The paper draws attention to the fact that the regions and municipalities of Russia have different economic potentials, differ in the volume and specificity of resources, have features of spatial position, etc., which determines the possibilities for the development of their competitive cooperation. In the process of research, general scientific methods were used, in particular the dialectical method, the unity of the historical and logical, abstractions, analogies, expert surveys, etc. The results of the study can be used in the development and implementation of strategies for the socio-economic development of regions and municipalities in the modern competitive economic space.
Development of Dark Stores as a Competitive Form of Delivery of Goods
Authors:   Synergy University, Chernukhina Galina G. , Ermolovskaya Оlga Yu. ,   Financial University under the Government of the Russian Federation
Published: December 2021

The aim of the scientific article is to study the transition of retail entities from the store format to the e-commerce format using the competitive advantages of dark stores. The subject of the research is competitive advantages when using high-tech and flexible forms of supply chains and in the delivery of goods. The relevance of the scientific article is due to the fact that the pace of development of online trade in 2018-2020 testifies to the growth of the largest companies in the e-commerce sector annually. This growth is due to high-tech trend trends that have been actively developing in recent years. They are structurally formed into a single system, the elements of which are: the use of Big data, the digital transformation of trade business processes, the integration of global marketing technologies, the use of smart forecasting and analysis of consumer behavior, personalization, orientation towards virtual content. This system is inherently aimed at the globalized development of trade relations. The authors investigate the essence of the concept of “dark store”, analyze the competitiveness of this phenomenon in e-commerce in modern conditions. Dark stores promote the development of a new generation of commerce, with competitive advantages, they do not interfere with existing production and distribution processes, but rather complement them. Currently, all large trade organizations of the food and non-food sectors are engaged in electronic commerce. First of all, online commerce is organized through online stores and marketplaces, but there are still many other electronic means of making a transaction - this is a page on a social network or a chatbot of a messenger, dark stores that require additional research. It is appropriate to characterize such marketplaces as aggregator sites playing the role of specialized structural intermediaries with a stable base engaged in the sale and distribution of the products of commercial agents. E-commerce in the dark store format thus contributes to the high-quality and competitive development of global economic ties.
Implementation of a Discount Policy the Shortage B2B Markets: a Marketing Ploy or Price Discrimination?
Authors:   Siberian Institute of Management – branch of RANEPA, Knyazeva Irina V. , Bondarenko Irina V. ,   Siberian Institute of Management – branch of RANEPA, Zaikin Nikolay N. ,   Siberian Institute of Management – branch of RANEPA
Published: December 2021

Modern research of B2B markets focuses on various aspects of information and economic interaction of market participants, but most often the features of marketing strategies in the field of promoting goods / services and building marketing communications are analyzed in order to increase customer satisfaction and loyalty. The issues of effective pricing and the implementation of discount policy as a tool to stimulate sales in B2B markets have not been practically studied. The variability in the application of seller pricing policy instruments in B2B markets under conditions of a limited number of buyers can have a significant impact on the intensity of competition in the market and, as a consequence, lead to a change in the market structure, its transformation and loss of balance. Therefore, the pricing system in non-equilibrium, in particular, shortage markets, in which the inefficient use of discount mechanisms by sellers can take the form of price discrimination of buyers due to the increased market power of the seller, is of considerable scientific and practical interest. This article, being a continuation of the discourse started by the authors on price discrimination in scarce markets, published in No. 3 of the journal Modern Competition, and is devoted to the study of the feasibility of using discounts in equilibrium and scarce B2B markets. At the end of the series of articles on price discrimination in scarce markets [1], the authors intend to publish a third article, which will examine the case of a shortage solid-rolled wheel market in Russia in 2018-2019 from the standpoint of assessing the feasibility of preserving discount programs for certain categories of buyers in the specified oligopolistic B2B market.
STIGMA SOSIAL PADA KELUARGA PASIEN CORONAVIRUS DISEASE 2019 DI KECAMATAN SUNGAILIAT KABUPATEN BANGKA
Authors: Elviera Firginia , Saputra Putra Pratama , Dedoe Amir
Published: December 2021

Penelitian ini mengenai stigma yang muncul dalam masyarakat Kecamatan Sungailiat Kabupaten Bangka yang ditujukan kepada keluarga pasien Coronavirus Disease 2019 yang belum tentu terinfeksi tetapi tetap mendapatkan stigma negatif dari masyarakat. Penelitian ini bertujuan untuk menggambarkan bentuk stigma sosial dan cara keluarga pasien Coronavirus Disease 2019 mengelola stigma yang diberikan masyarakat Kecamatan Sungailiat. Metode penelitian yang digunakan adalah metode kualitatif dengan jenis penelitian deskriptif. Data dikumpulkan melalui wawancara, observasi, dan studi kepustakaan. Peneliti menemukan bahwa masyarakat memberikan stigma kepada keluarga pasien Coronavirus Disease 2019 dengan pembatasan kontak sosial berupa perilaku mengucilkan, mengasingkan, menjauhi, dan menghindar yang disebabkan karena adanya rasa takut, waspada, dan kurangnya kerahasiaan dalam masyarakat. Keluarga pasien Coronavirus Disease 2019 melakukan pengelolaan stigma yaitu menuruti keinginan masyarakat untuk menjaga jarak dengan mereka serta tetap melakukan interaksi dengan masyarakat sekitar agar terlihat normal.
Kata Kunci: Coronavirus Disease 2019, Keluarga Pasien, Stigma Sosial
PENGARUH TAYANGAN MY TRIP MY ADVENTURE DI TRANS TV TERHADAP PENGETAHUAN WISATA SISWA
Authors: Tegar Tegar Prasetiyo , Agustari Tina
Published: December 2021

Televisi sebagai medium komunikasi massa memiliki fungsi informasi, mendidik, dan menghibur. Salah satu program TV yang memiliki fungsi tersebut adalah program My Trip My Adventure. Tujuan dari penelitian ini untuk melihat dampak dari tayangan My Trip My Adventure terhadap pengetahuan wisata siswa. Apakah siswa yang telah menonton tayangan My Trip My Adventure akan mendapatkan pengetahuan wisata. Pengaruh tersebut diungkap berdasarkan ketertarikan pada tayangan My Trip My Adventure dan ekspektasi pengembangan kemampuan kognitif individu terhadap informasi wisata dari tayangan ini. Metode penelitian yang digunakan adalah kuantitatif dengan paradigma positivisme. Penelitian dilakukan dengan pengumpulan data primer melalui survey, kemudian dianalisis dengan menggunakan metode analisis deskriptif. Populasi penelitian ini adalah siswa SMKN 29 Jakarta, kelas 10 tahun ajaran 2020-2021 yang berjumlah 338 siswa, dengan sampel minimal sebanyak 78 siswa. Hasil dari penelitian ini menunjukkan tayangan My Trip My Adventure yang menampilkan wisata Indonesia cenderung memengaruhi bagaimana individu memproses informasi tentang potensi wisata Indonesia dan ragam budaya Indonesia. Selain itu tayangan My Trip My Adventure yang mengedukasi untuk peduli lingkungan memengaruhi keputusan penonton untuk ikut menjaga alam. Kesimpulan dari penelitian ini adalah tayangan My Trip My Adventure di Trans Tv memberi pengaruh yang signifikan terhadap pengetahuan wisata siswa.
Kata kunci: Tayangan My Trip My Adventure, media televisi, pengetahuan wisata siswa.
THE ROLE OF THE 18TH ASIAN GAME IN THE PEACE OF THE KOREAN PENINSULA
Authors: Abdul Rodhi Nadia , Paksi Arie Kusuma
Published: December 2021

This journal examines the role of the 18th Asia Game as a diplomatic tool in the Korean peninsula conflict in 2018, specifically in promoting peace on the Korean Peninsula. This journal aims to describe and analyze the effectiveness of sports or Olympics affiliated with the Olympic Council of Asia (OCA) as a unifying tool in pushing for reunification opportunities on the Korean Peninsula. The 18th Asian Games, on the other hand, has played an essential role in uniting North and South Korea into one unit under the same flag in a variety of ways that have had a positive impact on peace between the two countries. This study employs qualitative research methods, such as literature review and triangulation, to collect data. A descriptive-analytical approach was used to collect and analyze data. This study's analysis employs sports diplomacy theory to examine the effectiveness of sports in resolving conflicts on the Korean Peninsula. Because the current state of the Korean peninsula has not entirely resulted in the ideals of the two countries' reunification, the theory of sports diplomacy can identify the factors that support the reduced intensity of the Korean Peninsula's cold war. One of the factors is the role of sport as a tool of sports diplomacy, which has increased opportunities for promoting peace and conflict resolution to reach a peace agreement between the two parties and eventually lead to reunification.
SÜTÇÜ İNEKLERDE ÖSTRUS SİKLUSUNUN, FOLİKÜLER GELİŞİMİN ve OVULASYONUN HORMONAL KONTROLÜ
Authors: CENGİZ Mehmet , TOHUMCU Vefa
Published: December 2021

Süt sığırcılığı işletmelerinde sürdürülebilir üretim ve verimlilik için en önemli faktörlerden biri döl verimidir. İşletme ölçeğine bağlı olarak, verimliliği artırabilmek için çeşitli yaklaşımlar kullanılmaktadır. Bunlar, seksüel aktivitenin gözlenmesi, sensör teknolojilerinin kullanımı, endokrin ölçümler ve hormon müdahaleleridir. Son elli yıl içinde, işletmelerdeki hayvan sayısının artışı, insan faktöründen kaynaklı kayıpları artırmıştır. Bu nedenle, sürülerde üremenin denetlenmesinde diğer teknolojik yaklaşımlara göre daha ucuz olan hormon uygulamaları yaygın hale gelmiştir. Bu amaçla prostaglandin F2-alfa (PGF2α) analogları, gonadotropin salıcı hormon (GnRH) analogları, progesteron, östradiol (E2), gebe kısrak serum gonadotropini (PMSG), insan koriyonik gonadotropini (hCG) gibi hormonlar veteriner hekimlikte geniş bir uygulama alanı bulmuştur. Üreme hormonlarının analog formlarının kullanımıyla çeşitli östrusun, foliküler gelişimin ve ovulasyonun senkronize edildiği programlar geliştirilmiştir. Bunların en yaygın kullanılanları, hedeflenmiş tohumlama programı, modifiye edilmiş hedef tohumlama programı, ov-synch, presenkronizasyon uygulanan ov-synch, progesteronla desteklenmiş ov-synch, double (çift) ov-synch programlarıdır.
Cultivos intercalados: una alternativa para aumentar los ingresos y la sostenibilidad de cafetales.
Authors: Jaramillo Santiago , Salazar Hugo Mauricio
Published: December 2021

La rentabilidad es un factor determinante para el caficultor al momento de tomar la decisión de establecer cultivos intercalados en las calles del cafetal, ya que su principal interés es tener un flujo positivo de ingresos adicionales, sin que se afecte la productividad del café. Otros factores que influyen en la adopción de la práctica de intercalamiento están relacionados con la disponibilidad de capital, los rendimientos alcanzables, los costos de producción, la facilidad de comercialización, el precio de venta y los riesgos asociados a la producción de nuevos cultivos.
Overdentures Supported by Mini or Conventional Implants-effect on Patient Satisfaction and Bone Resorption Rates. A Randomized Clinical Trial
Authors: Gaballa Osama Ahmed , Hamed Hamdy Abo El Fotouh , Fayyad Ahmed Emad , Rahhal Mohamed Marwan
Published: December 2021

AIM: The aim of the study was to assess the difference between patient satisfaction and bone height changes of mini-implant supported overdentures in comparison with conventional implant after bone expansion technique.

METHODS: This randomized clinical trial contains 36 edentulous participants with thin mandibular ridges randomly divided to receive 2 mini-implants, or 2 conventional implants after ridge splitting, both treatments were done in the inter-forminal area of the anterior mandible. Then, the patients received mandibular overdentures with ball and socket attachments. At base line, after 6 and 12 months of loading the implants, patients’ satisfaction was evaluated using visual analog scale, in addition to bone height changes using Soredex DIGORA Optime Classic software.

RESULTS: There was statistically significant difference in the overall satisfaction between the mini-implants and the conventional implants group; the amount of bone height changes in the mini-implant group was statistically significant less than the conventional implant group at base line, 6 and 12 months.

CONCLUSION: Treatment with two mini-implants provides high level of satisfaction and less bone height changes in a follow-up period of 12 months in comparison to conventional implants after ridge expansion.
Effect of Enhydra fluctuans on Kidney Function in Alloxan-induced Diabetic Rats
Authors: Delfita Rina , Dahelmi Dahelmi , Tjong Djong , Suhatri Suhatri
Published: December 2021

AIM: The aim of this study was to explore the effect of n-hexane fraction of Enhydra fluctuans aerial on kidney function in alloxan induced diabetic rats. METHODS: Five groups of diabetic Wistar rats were studied: Group 1 was given 0.5% Na-CMC (G0), group 2 was given glibenclamide 0.45 mg/kg (G1), groups 3, 4, and 5 were given a dose of n-hexane fraction 57.03, 114.06, and 171.09 mg/kg respectively. The experiment was completed in 21 days. Blood glucose was estimated on day 0 and day 21 of treatment. Histology of kidney, creatinine, and blood urea nitrogen (BUN) was examined. ANOVA was used to evaluate quantitative data, which was then followed by Duncan's new multiple range test (p < 0.05). RESULTS: Our results demonstrate that n-hexane fraction dosages of 57.03 mg/kg and 114,06 mg/kg significantly improved blood glucose profile, BUN, and creatinine in diabetic rats. Moreover, the dosage of 57.03 mg/kg is effective to counteract necrosis and fibrosis of kidney cells.   CONCLUSION: Our findings revealed that the administration of the n-hexane fraction of E. fluctuans aerial improved the kidney function of diabetic rats, especially at the dosage of 57.03 mg/kg. Therefore, E. fluctuans can be relied upon to be a drug to prevent the development of diabetes mellitus and diabetic nephropathy.
Cervical Hydatidiform Moles Pregnancy: Diagnosis and Treatment
Authors: Sastra Winata I Gede , Kusuardiyanto Popy , Aryana Made Bagus Dwi , Mulyana Ryan
Published: December 2021

Cervical partial hydatidiform mole is a rare condition and difficult to diagnose. A 39-year-old Balinese woman from Sanglah General Hospital, Bali, Indonesia complained vaginal bleeding with abdominal pain. The patient was diagnosed with a partial hydatidiform mole based on physical examination, ultrasound, beta HCG levels and pathology examinations. Mass evacuation surgery followed by arterial ligation to stop the bleeding and periodically examination of beta HCG levels was carried out until the 14th week after the procedure. Beta HCG decreased gradually to normal level and indicate no risk of trophoblastic malignancy. Establishing the early diagnosis significantly affects the outcome of patient.
Keywords: partial cervical hydatidiform mole, blighted ovum, pregnancy, diagnosis, therapy.
Mapping the economic loss of ecosystem services caused by the invasive plant species Antigonon leptopus on the Dutch Caribbean Island of St. Eustatius
Authors: Huisman Seringe , Jesse Wendy , Ellers Jacintha , van Beukering Pieter
Published: December 2021

Invasive species are a worldwide threat to biodiversity, especially on Caribbean islands. Through their impact on the structure and functioning of ecosystems, they also affect ecosystem services. Therefore, invasive species can have profound socio-economic effects. On the Dutch Caribbean Island of St. Eustatius, the invasive perennial vine Coralita is present on roughly 33% of the Island. While ecological damage is evident, effective management strategies are still lacking. This study links the ecological, cultural and societal effects of the invasion to the economy of the Island by estimating the ecosystem service losses due to Coralita in monetary value. We have spatially assessed the economic value of five main ecosystem services (tourism, non-use value, carbon sequestration, archaeology and local cultural and recreational value) to the different habitats on the Island and estimated the loss of these values under three scenarios of Coralita cover: 0%, 3% and 36% dominant cover. The baseline scenario of 0% demonstrated a total ecosystem service value of $2.7 million per year, concentrated on the Quill volcano. The 3% and 36% scenario showed a yearly loss of $39,804 and $576,704, respectively, with the largest losses located on the northern and eastern slopes of the Quill. These areas should be prioritised for management and the known potential gain per area enables choice of strategy, based on cost-benefit considerations. To reduce further economic loss by Coralita, we urgently advise an immediate management strategy and ongoing research into eradication and restoration methods.
Vicia mingyueshanensis (Fabeae, Papilionoideae, Fabaceae), a new species from western Jiangxi, China
Authors: Xiao Zhi-Yong , Li Xiao-Chun , Luo Ying , Zeng Chuan-Sheng , Qiu Bang-Gui , Cao Fu-Liang
Published: December 2021

Vicia mingyueshanensis, a new species from the Mingyue Mountain Region of western Jiangxi, China, is described and illustrated. It is a perennial climbing liana that always links to riparian woods. A morphological comparison indicated that the new species is closely similar to Vicia taipaica K. T. Fu and Vicia dichroantha Diels; however, it differs from the other two species by several salient characters, such as plant indumentum, stipule shape, corolla colour, bractlet shape and calyx shape. Photographs, a preliminary conservation assessment, table of morphological characters and distribution map comparing this new species to two morphologically-similar species are also provided.
Sur le seuil
Authors: Indirli Vincent
Published: December 2021

Avant le geste, avant l’acte, il y a le verbe et celui-ci, simple ou complexe, réfléchi ou ressenti, analysé, posé délicatement au-devant de l’autre ou l’emprisonnant, va, quoi que nous fassions ensuite, guider, façonner le geste, accompagner l’acte. Il nous faudrait être tout entier tourné vers celui qui exprime sa demande, vers ses proches, partageant avec tous ceux qui accompagnent, la complexité que revêt cette dite demande si particulière, dormir pour ne pas se voir mourir.
Entendre une demande d’une aide active à mourir : convocation à l’altérité, au temps, à l’inattendu
Authors: Legenne Myriam
Published: December 2021

L’ambivalence a, semble-t-il, continué à prendre largement place dans ses dernières semaines de vie et jusqu’à son décès, mais il a pu choisir. L’histoire de cet homme, de sa famille, mêlée aux soins et aux relations tissées avec les soignants, a permis un ajustement éthique et non idéologique. Cet ajustement est une parole germée des profondeurs, des soubassements d’une vie qui a pu, à un moment, perdre puis retrouver sens, autrement.
Recevoir et contenir ensemble la demande de mort
Authors: Le Jamtel Cyrille
Published: December 2021

Le propos de ce partage d’expérience n’est pas de nier l’existence chez certains patients d’un désir de mort. Il pose l’importance, pour tous les professionnels et bénévoles engagés dans l’accompagnement, de recevoir et contenir cet éprouvé plutôt que de tenter rapidement de le résoudre de manière défensive par des mécanismes de déni et d’évitement ou de manière plus radicale encore par un passage à l’acte. Plus que jamais, il est impératif de laisser vivre le désir de mort.
Comprendre et former à l’innovation : détours par la pensée complexe
Authors: Morel Laure , Rault Valérie
Published: December 2021

Former à l’innovation les nouvelles générations est devenu un enjeu unanimement reconnu. Cependant, force est de constater que les façons de concevoir les référentiels métiers ne sont pas génériques et procèdent trop souvent d’une logique de juxtaposition des compétences. Nous voulons dans cet article, rappeler l’expérience d’une école d’ingénieur, pionnière dans la compréhension et la mise en œuvre de la pensée complexe au sens d’Edgar Morin afin de former non pas à l’innovation mais aux processus innovants dans une approche ouverte et multi acteurs. En effet, rechercher à innover passe par des voies complexes dans la mesure où un projet d’innovation est producteur d’un résultat mais aussi producteur de son processus. Il ne se résume plus au fait de changer les structures, les produits ou les modes de travail, : les modes de raisonnement , les mentalités et les comportements sont impactés. Un détour par la pensée complexe est donc nécessaire.
Gene expression signature of exercise and change of diet on non-alcoholic fatty liver disease in mice
Authors: Melo L. , Hagar A. , Klaunig J.E.
Published: December 2021

Non-alcoholic fatty liver diseases (NAFLD) are particularly prevalent in the general Western adult population, with around one third of the population suffering from the disease. Evidence shows that NAFLD is associated with metabolic syndromes such as obesity, insulin resistance, and hypertension. Currently, the sole therapy for NAFLD involves exercise intervention. Studies showed that, with and without weight loss, exercise interventions produced a significant cutback in intrahepatic lipid content in humans, but better controlled studies that can investigate the cellular and molecular mechanisms are still lacking. In the current study we perform RNA sequencing analysis on liver samples from C57BL/6 mice submitted to aerobic exercise and diet interventions that are human-translatable and determine the genetic expression signature of exercise in the NAFLD onset. We show that aerobic exercise affects genes and pathways related to liver metabolism, muscle contraction and relaxation, immune response and inflammation, and development of liver cancer, counteracting non-alcoholic steatohepatitis and hepatocellular carcinoma development. While genes and pathways implicating immune response are activated by aerobic exercise in all interventions, the most effective intervention in terms of improvement of NASH is the combination of aerobic exercise with change of diet.
A degenerate bifurcation from simple eigenvalue theorem
Authors: Liu Ping , Shi Junping
Published: December 2021

A new bifurcation from simple eigenvalue theorem is proved for general nonlinear functional equations. It is shown that in this bifurcation scenario, the bifurcating solutions are on a curve which is tangent to the line of trivial solutions, while in typical bifurcations the curve of bifurcating solutions is transversal to the line of trivial ones. The stability of bifurcating solutions can be determined, and examples from partial differential equations are shown to demonstrate such bifurcations.
Factors Influencing the Postrelease Movements of Translocated Fishers: Implications for Translocation Success
Authors: Lewis Jeffrey C. , Happe Patricia J. , Jenkins Kurt J. , Manson David J.
Published: December 2021

Long-distance, postrelease movements of translocated wildlife can be a key factor limiting translocation success. Yet, for many species, we have little or no understanding of factors that influence postrelease movements. Translocations have been important for recovering fisher Pekania pennanti populations across the southern portion of their North American range. However, little is known about the postrelease movements of translocated fishers and how these movements may be influenced by demographic or translocation-process factors. To restore fishers in Washington State, we moved 90 fishers from central British Columbia and released them at nine sites in the Olympic Fisher Recovery Area on the Olympic Peninsula of Washington from 2008 to 2010. We evaluated postrelease movements of 48 fishers to determine both the distance and duration of movements prior to home range establishment. Fishers moved extensively following their release. Multimodel selection indicated a high level of support for the hypothesis that postrelease movements differed by fisher sex and age; whereas, year of release had no apparent effect on movements, and release date had only a marginal influence on movements. Mean distance (±95% CI) from a release site to a home range was greater for adult males (62.0 ± 19.6 km) than for juvenile males (31.4 ± 16.0 km), adult females (30.9 ± 21.1 km), and juvenile females (29.0 ± 13.5 km). Mean number of days from release until home range establishment was similar for the sexes; however, the variance in movement duration was greater for females. Twenty-six of 27 females established home ranges over an 11-mo period (December–October), while 19 of 21 males did so within a 4-mo period (April–July). Mean home range sizes differed between males (128.3 ± 21.1 km2) and females (63.5 ± 9.0 km2) and were among the largest reported for the species. A greater proportion of females (18 of 27; 67%) than males (8 of 21; 38%) established home ranges within or partially within the recovery area. Six females left a previously established home range during the breeding season, presumably to find breeding males. Given the large distances that fishers can move following release, translocation success could be furthered by releasing individuals at fewer sites in the interior of large reintroduction areas to facilitate greater exposure to a recovery area and greater opportunity to interact with conspecifics and potential mates.
Screening and Diagnosis of Autism Spectrum Disorder via Assistive Tools
Authors: Tuna Gurkan , Tuna Ayşe
Published: December 2021

Autism spectrum disorder (ASD) is a challenging developmental condition that involves restricted and/or repetitive behaviors and persistent challenges in social interaction and speech and nonverbal communication. There is not a standard medical test used to diagnose ASD; therefore, diagnosis is made by looking at the child's developmental history and behavior. In recent years, due to the increase in diagnosed cases of ASD, researchers proposed software-based tools to aid in and expedite the diagnosis. Considering the fact that most of these tools rely on the use of classifiers, in study, random forest, decision tree, k-nearest neighbors, and zero rule algorithms are used as classifiers, and their performances are compared using well-known performance metrics. As proven in the study, random forest algorithm can provide higher accuracy than the others in the classification of ASD and can be integrated into a computer- or humanoid-robot-based system for automated prescreening and diagnosis of ASD in preschool children groups.
Strategies, Tips, and Language to Support Parent and Educators Through the IEP Process
Authors: Francis Denise
Published: December 2021

This chapter provides strategies, tips, and language through the IEP process from the first person perspective of a parent turned parent-advocate. This chapter shares with educators what the experience is like from a parent side of the table and the emotions involved. It also is meant to help build a knowledge base for parents and encouragement from the author's perspective as a parent. Lastly, this chapter shows that there are ways to bring the student's voice into their IEP regardless of their communication ability.
Distribution of Wealth for Sustainable Happiness
Authors: Noor Sheakh Reyad Muhammad , Afroz Zobaida , Mousumi Ayesha Akter
Published: December 2021

The richest one percent of the entire population of the world now owns more than half of the global wealth which shows global wealth is unequally distributed. Moreover, this is assumed that sustainable growth is impossible based on impossibility theorem. Considering the above, the study has been conducted and critically overviewed the wealth distribution of an ancient period based on Islamic rules and practice. Upon study, it has been found that people are very much self-centered and unaware of the broader perspective like searching happiness instead of immediate wealth maximization. The finding has also shown that right of inheritances, relatives, neighbors, society, and state should be defined clearly and need distribution of wealth based on definition. If we become more self-centered, we will find ourselves helpless. Here, wealth means knowledge and physical assets.
U.S. Unemployment Rate Prediction by Economic Indices in the COVID-19 Pandemic Using Neural Network, Random Forest, and Generalized Linear Regression
Authors: Zhao Zichen , Hou Guanzhou
Published: December 2021

Artificial neural network (ANN) has been showing its superior capability of modeling and prediction. Neural network model is capable of incorporating high dimensional data, and the model is significantly complex statistically. Sometimes, the complexity is treated as a Blackbox. However, due to the model complexity, the model is capable of capture and modeling an extensive number of patterns, and the prediction power is much stronger than traditional statistical models. Random forest algorithm is a combination of classification and regression trees, using bootstrap to randomly train the model from a set of data (called training set) and test the prediction by a testing set. Random forest has high prediction speed, moderate variance, and does not require any rescaling or transformation of the dataset. This study validates the relationship between the U.S. unemployment rate and economic indices during the COVID-19 pandemic and constructs three different predictive modeling for unemployment rate by economic indices through neural network, random forest, and generalized linear regression model.
Torrent Monitoring and Early Warning Systems Development
Authors: Vasović Dejan , Ristić Ratko , Bajrić Muhamed
Published: December 2021

The level of sustainability of a modern society is associated with the ability to manage unwanted stressors from the environment, regardless of origin. Torrential floods represent a hydrological hazard whose frequency and intensity have increased in recent years, mainly due to climate changes. In order to effectively manage the risks of torrents, it is necessary to apply early warning systems, since torrential floods are formed very quickly, especially on the watercourses of a small catchment area. The early warning system is part of a comprehensive torrential flood risk management system, seen as a technical entity for the collection, transformation, and rapid distribution of data. Modern early warning systems are the successors of rudimentary methods used in the past, and they are based on ICT and mobile applications developed in relation to the requirements of end users. The chapter presents an analysis of characteristic examples of the use. The main conclusion of the chapter indicates the need to implement early warning systems in national emergency management structures.
Teacher Identity, Growth Mindset, and Agency
Authors: LaFrance Diane , Rakes Lori
Published: December 2021

This chapter discusses the problem of teacher retention as it relates to handling the unexpected, whether it be meeting the needs of all learners, classroom management, or any other problem teachers may encounter. The authors propose that teacher education programs can support the growth of preservice teachers by helping them to develop teacher identity early in their learning through experiences and autonomy. In addition, preservice teachers should develop a growth mindset to promote agency when encountering learning obstacles and to engage in reflective practice. By identifying as teachers, allowing themselves to grow, and being proactive in searching for ways to improve their practice, preservice teachers can better prepare themselves for the reality of teaching and, hopefully, remain in the teaching profession.
Skill Acquisition
Authors: Adeniyi Bolaji Comfort
Published: December 2021

The purpose of the study was to examine the extent to which skill acquisition would influence economic development in Nigeria. The descriptive research design of the survey type was adopted in the study. The population of this study comprised all the students of government technical colleges in Southwest Nigeria. The reliability of the instrument was estimated using Chronbach's Alpha reliability method. The data collected for this study was analyzed using both descriptive and inferential statistics. The result of the study revealed that skill acquisition program has a positive and significant effect on the ability of students of technical colleges in Southwest Nigeria to be self-reliant at graduation; skill acquisition program has a positive and significant effect on the ability of students of technical colleges in Southwest Nigeria to produce goods for local consumption. It was also recommended based on the study that the various government parastatals should review, standardize, and expand the curricula of all skill acquisition schemes in Nigeria among others.
Persistence of T Cell and Antibody Responses to SARS-CoV-2 Up to 9 Months after Symptom Onset
Authors: Law Jaclyn C , Girard Melanie , Chao Gary Y C , Ward Lesley A , Isho Baweleta , Rathod Bhavisha , Colwill Karen , Li Zhijie , Rini James M , Yue Feng Yun , Mubareka Samira , McGeer Allison J , Ostrowski Mario A , Gommerman Jennifer L , Gingras Anne-Claude , Watts Tania H
Published: December 2021

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces T cell, B cell, and Ab responses that are detected for several months in recovered individuals. Whether this response resembles a typical respiratory viral infection is a matter of debate. In this study, we followed T cell and Ab responses in 24 mainly nonhospitalized human subjects who had recovered from PCR-confirmed SARS-CoV-2 infection at two time points (median of 45 and 145 d after symptom onset). Ab responses were detected in 95% of subjects, with a strong correlation between plasma and salivary anti-spike (anti-S) and anti—receptor binding domain IgG, as well as a correlation between circulating T follicular helper cells and the SARS-CoV-2–specific IgG response. T cell responses to SARS-CoV-2 peptides were determined using intracellular cytokine staining, activation markers, proliferation, and cytokine secretion. All study subjects had a T cell response to at least one SARS-CoV-2 Ag based on at least one T cell assay. CD4+ responses were largely of the Th1 phenotype, but with a lower ratio of IFN-γ– to IL-2–producing cells and a lower frequency of CD8+:CD4+ T cells than in influenza A virus (IAV)-specific memory responses within the same subjects. Analysis of secreted molecules also revealed a lower ratio of IFN-γ to IL-2 and an altered cytotoxic profile for SARS-CoV-2 S- and nucleocapsid-specific responses compared with IAV-specific responses. These data suggest that the memory T cell phenotype after a single infection with SARS-CoV-2 persists over time, with an altered cytokine and cytotoxicity profile compared with long-term memory to whole IAV within the same subjects.
Association between breastfeeding and breast, thyroid, and cervical cancer among Korean adult women: based on the Korean Genome and Epidemiology Study
Authors: Jin Eunju , Kang Hyunju , Son Mia
Published: December 2021

Purpose: The purpose of this study was to explore the relationship between breastfeeding and the prevalence of breast, thyroid, and cervical cancer among Korean adult women.Methods: The study was a secondary analysis of data from the Korea Genome and Epidemiology Study. The final samples were 113,944 Korean women among 173,205 urban-based cohort participants collected between 2004 and 2013 for adults aged forty and over. To determine the association between female cancers and breastfeeding experience, the number of childbirth, and total breastfeeding duration, logistic regression analysis was done. The demographic characteristics, health behavior, and female history were adjusted.Results: The prevalence of breast cancer was 1.37 times higher in non-breastfeeding group than in breastfeeding group. Compared to having breastfed for more than 36 months, the prevalence of thyroid cancer was 1.68 times higher at breastfeeding for 13 to 36 months, 1.67 times higher at breastfeeding for 6 to 12 months, and 2.06 times higher at breastfeeding less than 6 months. Also, the prevalence of cervical cancer was 1.54 times higher at breastfeeding for 13 to 36 months compared to breastfeeding for more than 36 months.Conclusion: The study provides that breastfeeding experience and the longer breastfeeding duration have reduced the risk of breast, thyroid, and cervical cancer in Korean women. It can be used as a basis for encouraging breastfeeding, which is identified to reduce the risk of breast, thyroid, and cervical cancers in Korean women.
Effects of a newborn care education program using ubiquitous learning on exclusive breastfeeding and maternal role confidence of first-time mothers in Vietnam: a quasi-experimental study
Authors: Nguyet Tran Thi , Huy Nguyen Vu Quoc , Kim Yunmi
Published: December 2021

Purpose: This study aimed to examine the effect of a newborn care education program using ubiquitous learning (UL-NCEP) on exclusive breastfeeding and maternal role confidence of first-time mothers.Methods: This quasi-experimental study with a nonequivalent control group design was conducted at a university hospital in Hue city, Vietnam between June and July 2018. Eligible first-time mothers were conveniently allocated to the experimental (n=27) and the control group (n=25). Mothers in the control group received only routine care, whereas mothers in the experimental group received UL-NCEP through tablet personal computers in addition to routine care in the hospital. Then, the educational content was provided to mothers by their smartphone for reviewing at home. UL-NCEP was developed based on the World Health Organization’s “Essential Newborn Care Course” guidelines. The exclusive breastfeeding rate and maternal role confidence level after birth and at 4 weeks postpartum were assessed in both groups to assess the effect of UL-NCEP.Results: At 4 weeks postpartum, the experimental group showed a significantly higher level than the control, for exclusive breastfeeding rate (p<.05) as well as mean maternal role confidence (p<.05).Conclusion: UL-NCEP was a feasible and effective intervention in increasing first-time Vietnamese mothers’ exclusive breastfeeding rate and maternal role confidence level. This program may be integrated into routine care for postpartum mothers to promote mother and infant health among first-time mothers in Vietnam.
Sickle Cell Disease Complications
Authors: Voskaridou Ersi
Published: December 2021

Sickle cell disease (SCD) is an inherited, lifelong condition. The sickle mutation consists a single nucleotide change (GAT->GTT) in the sixth codon of exon 1 of the β-globin gene coding for the β-globin polypeptide of hemoglobin (Hb) (a2β2). This change results in replacement of the wild type glutamic acid residue by a valine residue in β-globin chain and the formation of the sickle Hb (HbS) in homozygotes for this mutation. Heterozygotes live a normal life. In SCD patients, sickle erythrocytes are rigid with decreased deformability and reduced life span resulting in hemolysis, vaso-occlusive disease, vasculopathy and subsequent inflammation and end organ damage. Sickle cell disease affects millions of people worldwide. Today, with proper health care, many SCD patients have a good quality of life (QoL) and are in fairly good health most of the time. These people can live up to their forties or fifties, or longer. Despite the ‘common’ underlying genetic basis and a similar pathophysiology, patients with SCD present a highly variable clinical phenotype due to Single Nucleotide Polymorphisms (SNPs) variability throughout the genome. Patients with SCD are at high risk for developing multisystem acute and chronic complications associated with significant morbidity and mortality.
e-ENERCA: Telemedicine Platform for Rare Anaemias
Authors: Gulbis Béatrice , del Mar Mañú Pereira María , Armaza Armaza Emilio J. , Nicolás Pilar ,   for the ENERCA Working Group
Published: December 2021

The creation of a telemedicine, tele-expertise platform opens a new challenge within the European Network for Rare and Congenital Anaemias (ENERCA; www.enerca.org). This is a cornerstone in the field of rare anaemias, in which national expertise is usually scarce and a significant number of patients remain undiagnosed. Experts in rare diseases are specially needed of shared knowledge platforms offering the possibility of a faster and more accurate diagnosis and the availability of a better patients’ follow-up. The platform developed by e- ENERCA will be user friendly and intuitive so it will be used by the majority of professionals without requiring a specific formation. The idea of inter professional consultation is to bring medical experts together for collaborative involvement in activities that maximize the benefits and improvement in patient care.