bluuebunny/crossref_metadata_2025 huggingface dataset:
Laryngeal sarcoidosis: An adult presenting with ENT manifestations to a tertiary referral centre
Authors:   Department of Otolaryngology, Charring Cross Hospital, Imperial College Healthcare NHS Trust, London, UK., Mehtani Nikita , Thong Gerard ,   Department of Otolaryngology, Charring Cross Hospital, Imperial College Healthcare NHS Trust, London, UK., Al-Yaghchi Chadwan ,   Department of Otolaryngology, Charring Cross Hospital, Imperial College Healthcare NHS Trust, London, UK., Sandhu Gurpreet ,   Department of Otolaryngology, Charring Cross Hospital, Imperial College Healthcare NHS Trust, London, UK.
Published: March 2022

A 55-year-old lady female presents to the clinic complaining of hoarseness of voice, difficulty swallowing and breathlessness on exertion. This was associated with dryness and crusting in her nose. She underwent flexible nasoendoscopy, which was suggestive of supraglottic oedema with nodules over the back of the epiglottis. She subsequently underwent microlaryngoscopy and biopsy of the lesions. The histopathology confirmed the diagnosis of laryngeal sarcoidosis. She was treated with laser debulking, serial intralesional steroid injections, balloon dilatation to aid with her symptoms. Sarcoidosis is a multisystemic inflammatory disease with extrathoracic manifestations, most commonly affecting the young and middle-aged, female, and black populations. Diagnosis usually requires evidence of non-caseating granulomata and, when treated, prognosis is usually favourable.
Rare case of COVID-19 pneumonia in a neonate
Authors:   Paediatrics Department, Prince Charles Hospital, Cwm Taf University Hospital Health Board, Merthyr Tydfil, United Kingdom., Omolokun Omotakin , Elhassan Hiba ,   Paediatrics Department, Prince Charles Hospital, Cwm Taf University Hospital Health Board, Merthyr Tydfil, United Kingdom.
Published: March 2022

Children infected with COVID-19 are often asymptomatic or with very mild symptoms [1]. While the risk of vertical transmission has not been fully elucidated [2], it is less common for newborns to have serious infection. We report a case of a 9-day old with COVID-19 Pneumonia requiring mechanical respiratory support.
Inflammatory cytokines and cell activation markers in HIV and HIV/TB co-infected patients attending AMPATH clinic at MTRH-Eldoret, Kenya
Authors:   Moi university, School of medicine, Eldoret, Kenya., Undisa Rose , Awuor Silas O ,   Ministry of Health, Masogo Sub county hospital, Kisumu County, 12-40122, Kisumu, Kenya., AK Chemtai ,   Moi university, School of medicine, Eldoret, Kenya., LO Diero ,   Moi university, School of medicine, Eldoret, Kenya.
Published: March 2022

Background: Infection with HIV and TB leads to inflammation. Markers of inflammation include TNF-α, IFN-γ, CD38 and HLA-DR. In HIV infection these markers create an environment which favours reactivation of latent TB to TB disease in patients on HAART. The markers TNF-α, IFN-γ, CD38, HLA-DR and CD4 cell count can be used to predict possible reactivation of latent TB to disease in HIV patients on HAART. The level of these inflammatory markers in HIV and HIV/TB co-infection is unknown. The purpose of this study was to investigate inflammatory markers TNF-α, IFN-γ, CD38, and HLA-DR levels in HIV and HIV/TB coinfected patients attending AMPATH clinic at MTRH-Eldoret. Objective: To determine inflammatory cytokines and cell activation markers in HIV and HIV/TB co-infected patients attending AMPATH clinic at MTRH-Eldoret. Methods: This was a cross sectional comparative study of 168 patients comprising of 84 HIV/TB co-infected and 84 HIV only patients who had been on HAART for more than 1 year. Clinical and demographic information was obtained from the patients hospital files and interview guide. Blood samples from each patient were collected into EDTA tubes and plasma separated within 2 hours of collection at 3,000 r.p.m for 3 minutes then kept at -800 C until analysis. Activation markers CD38, HLA DR and CD4 count were analysed by flow Cytometry (BD FAC’S calibur® ) on whole blood samples. Analysis of the inflammatory cytokines (TNF-α and IFN-γ) were done on the plasma samples by ELISA (Genway’s® ). The levels of inflammatory markers in the two groups were compared. Data was analysed using STATA version 13. P-value ≤ 0.05 was considered significant. Findings: The mean age for both HIV/TB and HIV patients was 42 years. The median (IQR) levels for TNF-α (pg/ml) was 7.26 (6.76- 8.12), IFN-γ (pg/ml) 26.3 (25.18- 27.22), CD38(%) 4.36 (2.06-6.31), HLA-DR (%) 92.44 (90.52-95.51) and CD4 (cells/mm3 ) 231 (117-350) in HIV/TB co-infected patients, while in HIV patients the levels were TNF-α 10.72 (8.12-12.13), IFN-γ 25.40 (23.59-27.67), CD38 5.94 (4.44-7.41), HLA-DR 93.33 (90.24-96.56) and CD4 383 (318-543). HIV only patients had higher levels of TNF-α (p=<0.001), CD38% (p=0.0002) and CD4 (p=<0.001) compared to those of TB/HIV co-infected patients. No significant difference was observed in the levels of IFN-γ and HLA-DR (p=0.1559) and (p=0.1754) respectively. Conclusion: Higher levels of inflammatory markers were found in HIV only patients compared to HIV/TB co-infected patients. This high level of inflammation leads to TB-reactivation. Keywords: inflammatory cytokines; cell activation marker; HIV and HIV/TB co-infected.
Non radiographic axial spondyloarthropathy in tuberculoid leprosy
Authors:   Professor and Dean (Retired), Faculty of Medicine, Institute of Medical Science, Banaras Hindu University B 15/14-A2, Faridpura, Varanasi-221001, India., Bhattacharya Sujit Kumar
Published: March 2022

Rationale: Axial Spondyloarthirtis (ax-SpA) includes a non-radiographic variant, called Non Radiographic Axial Spondyloararthrophy (nr-ax-SpA), which is a very rare type of arthritis of spine. Hansen disease or Leprosy is a chronic infectious disease with various clinical manifestations, which is endemic in India. Various arthritic manifestations have been reported in leprosy patients. Though the condition is treatable and reversible, it may remain unrecognized and undisclosed in patients suffering with Leprosy. Patient concern: Here we illustrate a case of non-radiographic axial spondyloararthrophy in 40-year old male with diagnosis of borderline Hansen’s disease (leprosy) 15 years ago. Patient had reported chronic back pain for over five years, leading to stiffness of dorsal spine, and presented swollen wrist joint. Leprosy symptoms presented include dry hyper-pigmented, non-ulcerating, hypo-aesthetic (pain and temperature) patches on both legs, buttocks, upper abdomen and iliac crest. Diagnosis: The patient was diagnosed as border line tuberculoid leprosy with nr-ax-SpA. Treatments: He was treated with in domethacin, leflunomide and hydroxy-chloroquine, along with a standard treatment regimen to combat BT Leprosy. Follow up at 3 and 6 month revealed significant improvement. Keywords: spondyloarthritis; leprosy; hydroxy-chloroquine.
Unusual inhalation of a tissue piece in an infant
Authors: Imad Najoua , Lahmini Widad , Bourrous Mounir
Published: March 2022

Foreign body inhalation is a major problem in children and is one of the most serious accidents in early childhood. It is considered a common cause of childhood morbidity and mortality. We present a unique and unusual case of inhalation of a piece of tissue in a 10-month-old infant admitted to the Pediatric Emergency Department of the Mohamed VI Teaching University Hospital in Marrakech in 2021. The patient was initially seen with acute dyspnea, persistent dry cough, and signs of respiratory distress. The auscultation revealed decreased vesicular murmurs in the right lung field. Chest radiography did not reveal the presence of the foreign body, justifying the use of rigid bronchoscopy for diagnostic and therapeutic purposes, and revealing the presence of a tissue in the bronchial area. Our case report is distinguished by the strange and atypical nature of the foreign body not reported in the literature. Prevention especially parental education is recommended to reduce the morbidity and mortality associated with this domestic accident. Keywords: foreign body; aspiration; choking; bronchoscopy.
Impact of the COVID-19 declaration of the state of emergency on weekly trends in the care of asthma and COPD in Japan: A retrospective and descriptive study
Authors:   Department of Hygiene, Public Health and Preventive Medicine, Showa University School of Medicine, Tokyo, Japan., Minoura Akira , Murakami Kouzou ,   Department of Radiology, Division of Radiology, Showa University School of Medicine, Tokyo, Japan., Matoba Masaaki ,   Department of Health Management, Showa University Graduate School of Health Sciences, Tokyo, Japan., Ito Yoshinori ,   Department of Radiology, Division of Radiology, Showa University School of Medicine, Tokyo, Japan., Kamijo Yumi ,   Department of Health Management, Showa University Graduate School of Health Sciences, Tokyo, Japan., Kokaze Akatsuki ,   Department of Hygiene, Public Health and Preventive Medicine, Showa University School of Medicine, Tokyo, Japan.
Published: March 2022

Introduction: To examine trends in respiratory diseases other than infectious diseases is important for public health issue during coronavirus disease 2019 (COVID-19) pandemic. This study aimed to examine the trends in patient consultations for asthma and Chronic Obstructive Pulmonary Disease (COPD) at Show a University Hospital in Japan during the COVID-19 declaration of the state of emergency. Methods: This study designed as a retrospective and descriptive study. Subjects were 6,483 patients who had received medical treatment at Show a University Hospital and were diagnosed asthma or COPD from 2017 to 2020. To examine the impact of the COVID-19 declaration of the state of emergency, the number visits to hospital by asthma were summarised from January to September, for each year. Results: Compared to the average of the previous 3 years, a comparison of the three periods (before, during and after the COVID-19 declaration of the state of emergency) showed a V-shaped curve in 2020, with a large drop in the number of asthma and COPD patients during the COVID-19 declaration of the state of emergency. The number of patients recovered after the COVID-19 declaration of the state of emergency was lifted, but not returned to the pre-declaration level. Conclusions: This study showed a long-term decrease in asthma and COPD patients visits to Show a University Hospital since the beginning of the COVID-19 pandemic compared to the previous 3 years. It is also possible that medical care that would have been available may not have been provided due to the COVID-19 declaration of the state of emergency, so it is necessary to follow up patients while keeping a close eye on measures other than infectious diseases. Keywords: asthma; COPD; the COVID-19 declaration of the state of emergency; infection control; japanese.
Per oral endoscopic myotomy (POEM) in a COVID-19 patient
Authors:   Gastroenterology Division, Internal Medicine Department, Faculty of Medicine, Cairo University, Egypt., Elkholy Shaimaa , Essam Kareem ,   Gastroenterology Division, Internal Medicine Department, Faculty of Medicine, Cairo University, Egypt., El-Gazzarah Ahmed Ragab ,   Tropical Medicine Department, Faculty of Medicine, Menoufia University, Egypt., Gamal Gina ,   Gastroenterology Division, Internal Medicine Department, Faculty of Medicine, Ain shams University, Egypt., Abdellatif Abeer Awad ,   Gastroenterology Division, Internal Medicine Department, Faculty of Medicine, Cairo University, Egypt., El-Sherbiny Mohamed ,   Gastroenterology Division, Internal Medicine Department, Faculty of Medicine, Cairo University, Egypt.
Published: March 2022

Background: SARS-COV2 pandemic had a great impact on our life. Changes had been done to accommodate the current situation. Infection control measures in the endoscopy units had entirely changed. Also, prioritizations of different procedures had changed especially in the lockdown time. Peroral Endoscopic Myotomy (POEM) is considered a low priority endoscopic procedure. Case presentation: We report a 12-year-old child complaining of dysphagia and weight loss who was diagnosed as Type II achalasia. She underwent POEM. According to our Egyptian protocol; COVID-19 was excluded pre-procedural. After POEM, immediately post-procedural chest X-ray was done as usual, and it showed a shadow in the right lung base. Accordingly, HRCT of the chest was done and it showed bilateral asymmetrical patchy areas of ground-glass opacities in the posterior segments of both lower lung lobes (CO-RADS 4). PCR for COVID-19 was positive. Conclusion: We report a very unique COVID-19 case that raises many challengeable issues and shows a useful message about the risk of silent COVID-19 infection in children during the endoscopy. Keywords: achalasia; Poem; 3rd Space endoscopy; COVID-19.
Too close for comfort: A case of extrinsic compression of the left ventricle by a large hiatal hernia
Authors:   Department of Medicine, Reading Hospital, Tower Health System, West Reading, Pennsylvania, USA., Oke Ibiyemi , Shah Smit ,   Department of Medicine, Reading Hospital, Tower Health System, West Reading, Pennsylvania, USA., Reggio Christopher ,   Department of Medicine, Reading Hospital, Tower Health System, West Reading, Pennsylvania, USA., Gupta Riju ,   Department of Medicine, Reading Hospital, Tower Health System, West Reading, Pennsylvania, USA., Reddy Rajesh ,   Department of Medicine, Reading Hospital, Tower Health System, West Reading, Pennsylvania, USA.
Published: March 2022

A 77-year-old man with a history of Coronary artery disease, COPD, and pulmonary fibrosis on 5 L of oxygen at home presented to the emergency department with dizziness. Vital signs at presentation included temperature 37°C, pulse 160/min, blood pressure 86/60 mmHg, respiratory rate 24/min, oxygen saturation 96% on 5 L of oxygen. He had end-inspiratory crackles on lung auscultation. His labs were unremarkable, but he had atrial fibrillation with a ventricular rate of 162 and non-specific T wave changes on EKG. Chest X-ray showed prominent interstitial markings representing fibrosis, and Chest CT revealed a large hiatal hernia with left pleural thickening and worsening emphysema. Transthoracic Echocardiogram (TTE) showed an Ejection fraction of 75%, extrinsic compression of the inferior, lateral, and inferolateral wall, and impaired relaxation. Other Echocardiographic findings were extrinsic compression of the left atrium, dilated right atrium, moderate tricuspid regurgitation, and estimated right ventricular systolic pressure of at least 96 mmHg (Figures 1a,b&c).
Bony deformities in a child with untreated osteogenesis imperfecta type III
Authors:   University of Arizona College of Medicine, Phoenix, 475 N 5th St., Phoenix, AZ 85004, USA, Vij Neeraj , V Belthur Mohan ,   Phoenix Children’s Hospital, Department of Orthopedics, Main Building, Clinic B, 1919 E, Thomas Rd, Phoenix, AZ 85016, USA.
Published: March 2022

Osteogenesis Imperfecta (OI) is a skeletal dysplasia that affects the cross-linking of Type 1 collagen leading to a wide spectrum of manifestations including bony abnormalities, scleral abnormalities, dentinogenesis imperfecta, and hearing abnormalities [1]. Orthopedic manifestations of OI include basilar invagination, kyphoscoliosis, codfish vertebrae, bowing deformities of the long bones, coxa vara, protrusion acetabuli, pathologic fractures, and radial head dislocations [1]. The Sillence Classification, originally designed to describe Types I – IV, has been expanded upon to includes Type V, VI, VII, which do not have a Type I collagen mutation, and instead have other genetic explanations (CRTAP, LEPRE1 genes) for the abnormal bone seen on microscopy [1,2]. Type I, IV represent milder forms of disease, Type V-VII represent milder forms of disease, Type III is the most severe survivable form, and Type II is lethal at birth [1,2]. We present a case of Sillence Type III OI, diagnosed by genetic analysis at birth, with significant bony deformities. She did not have appropriate multidisciplinary medical management of her condition and presented to our clinic at age 14. Radiographs of the spine and extremities demonstrated kyphoscoliosis, bilateral protrusio acetabuli, multiapical bowing bony deformities of femora, tibia, humeri, forearm, radial head dislocations, and short stature. This case highlights the importance of multidisciplinary management for children with OI. This includes physical rehabilitation [3], bisphosphonates [3,4] and more recently gene therapies [3,4], and stem cell transplantation therapies [4]. Patients with Osteogenesis Imperfecta Type III have a limited lifespan [5] and it is important to maximize the advantage of medical therapies. In the absence of the appropriate medical care, osteogenesis imperfecta can develop progressive deformities in the long bones, a high risk of fragility fractures, and progressive kyphoscoliosis that can be difficult to manage surgically due to underlying osteopenia.
Our cases of monoclonal gammopathy renal significance (MGRS): Single center experience
Authors:   Department of Nephrology, Lütfi Kırdar Resarch and Training Hospital, Istanbul, Turkey, Yadigar Serap , Parmaksiz Ergün ,   Department of Nephrology, Lütfi Kırdar Resarch and Training Hospital, Istanbul, Turkey
Published: March 2022

Objective: To analyze the clinical, pathological spectrum and prognosis of patients with Monoclonal Gammopathy of Renal Significance (MGRS). Methods: Patients with kidney biopsy-proven MGRS at Dr Lütfi Kırdar City Hospital between 2015 and 2019 were included, clinical data, kidney pathology type, treatment and prognosis were collected. Results: Thirteen patients, constituting 0.77% of kidney biopsies, were recorded. Eight MGRS patients had amyloidosis. 2 patients had monoclonal immunoglobulin deposition disease. 1 patient with proliferative glomerulonephritis with monoclonal immunoglobulin (G) deposits, 1 patient with cryoglobulinemic glomerulonephritis and one patient with C3 glomerulonephritis. All of our patients were treated with chemotherapy and/or stem cell transplantation. The mean follow-up period was 26 ± 34 months. Multiple myeloma developed in one patient at 19 months during follow-up. At the end of the follow-up, 2 patients (%) died, 3 patients (%) developed End-Stage Renal Disease (ESRD). Conclusion: MGRS is a rare form of hematological disorder that causes kidney damage presenting with a wide range of pathological lesions. Amyloidosis is the most common form. Early diagnosis and close follow-up are important because renal survival of MGRS patients can be improved with early treatment. Keywords: monoclonal gamopaties; renal injury; proteinüria.
Complete anterior capsule phimosis after routine cataract surgery
Authors:   Institut Arthur Vernes, 36 rue d’Assas 75006, Paris, Jumeau Aliénor Vienne , Guedj Mikaël ,   Institut Arthur Vernes, 36 rue d’Assas 75006, Paris
Published: March 2022

A 79-year-old woman with pseudoexfoliation and zonular weakness underwent routine phacoemulsification with 5.5 mm capsulorhexis and implantation of posterior chamber intra-ocular hydrophobic lens (KSSPStaar®). Examination at one-week post-surgery was normal. One-month post-surgery, the vision had decreased to 20/200. Slit-lamp examination showed complete anterior capsular contraction syndrome with a thick central occluding membrane and decentered lens (Figure 1A). No inflammation of the anterior segment was noted. Because of the zonular weakness, YAG laser anterior capsulotomy was chosen rather than further intra-ocular surgery with scissors and cystotome. Radial impacts, performed as usual, failed to clear the thick central membrane, so we detach edit and let the operculum drop away from the visual axis (Figure 1B). This procedure allowed for visual clearance and 20/20 vision recovery.
Case of Geotrichum capitatum septicemia successfully resolved by the use of liposomal amphotericin B in a patient with acute myeloid leukemia
Authors:   Hematology Unit, AO of Cosenza, Cosenza, Italy, Vigna Ernesto , Caracciolo Daniele ,   Hematology Unit, AO of Cosenza, Cosenza, Italy, Perugini Daniela ,   Hematology Unit, AO of Cosenza, Cosenza, Italy, Martino Enrica ,   Hematology Unit, AO of Cosenza, Cosenza, Italy, Mendicino Francesco ,   Hematology Unit, AO of Cosenza, Cosenza, Italy, Lucia Eugenio ,   Hematology Unit, AO of Cosenza, Cosenza, Italy, Botta Cirino ,   Hematology Unit, AO of Cosenza, Cosenza, Italy, Morelli Rosellina ,   Internal Medicine Department, AO of Cosenza, Cosenza, Italy., Barbato Angelo ,   Direzione Sanitaria, AO of Cosenza, Cosenza, Italy., Greco Francesca ,   Microbiology and Virology Unit, AO of Cosenza, Cosenza, Italy, Gentile Massimo ,   Hematology Unit, AO of Cosenza, Cosenza, Italy
Published: March 2022

Background: Geotrichum capitatum infection is a rare condition and it has only been reported in immune-compromised patients. The prognosis is poor, with a mortality rate between 50-90%. Case presentation: Here we report a case of Geotrichum capitatum septicemia in a neutropenic patient undergoing induction chemotherapy for acute myeloblastic leukemia. At day +24 from the beginning of chemotherapy, the patient’s blood cultures were positive for Geotrichum capitatum. When we received the antimicogram a therapy with liposomal amphotericin B (3 mg/kg/day) was started. After 15 days of antifungal treatment, the patient’s clinical condition had dramatically improved and at the twenty-first day of antifungal treatment the blood culture was negative for Geotrichum capitatum. On day +47 from the start of induction, the patient died in hematological remission of AML due to sudden death. An autopsy was not performed. Conclusion: This clinical case highlights the emergence of Geotrichum capitatum as an opportunistic fungus in Italian leukemia patients. Moreover, our case report shows how liposomal amphotericin B could represent an effective therapeutic approach for these infections. Further studies are needed to shed more light on these rare fungal infections, in order to define the best therapeutic approach towards invasive geotrichosis. Keywords: geotrichum capitatum; fungemia; neutropenia; acute myeloid leukemia.
Pengaruh leverage, likuiditas, dan capital intensity terhadap tax avoidance dengan komite audit sebagai variabel moderating
Authors: Khasanah Fitriyatul , Indriyani Fany
Published: March 2022

The purpose of this study was to determine the effect of Leverage, Liquidity, and Capital Intensity on Tax Avoidance with Audit Committee as a Moderating Variable in Companies Listed in the Jakarta Islamic Index (JII) 2015-2020. This research is included in the category of quantitative research with a sample selection model using purposive sampling. The selected sample is eight companies. The research data was analyzed using the moderated regression analysis method. The results showed that partially the leverage variable had a negative and significant effect on tax avoidance. The liquidity variable had a negative and insignificant effect on tax avoidance. The capital intensity variable had a positive and insignificant effect on tax avoidance. Meanwhile, simultaneously the variables of leverage, liquidity, and capital intensity cannot affect tax avoidance (ETR). Based on the Moderated Regression Analysis (MRA) test results, the moderating variable is that the audit committee can moderate the effect of leverage on tax avoidance, and the audit committee cannot moderate the effect of liquidity and capital intensity on tax avoidance.
Pengungkapan islamic social reporting yang dimoderasi komisaris independen dengan teknik moderated regression analysis
Authors: Safitri Febrianti , Rofiuddin Mohammad
Published: March 2022

The purpose of this study is to obtain empirical evidence regarding the effect of firm size, profitability, and leverage on the disclosure of Islamic social reporting (ISR) with independent commissioners as moderating variables. This study applies secondary data in the form of panel data from the annual financial statements of 11 Islamic commercial banks in 2016-2020 through the purposive sampling technique. The analytical technique used is multiple linear analysis and moderated regression analysis (MRA). The research proves that firm size and leverage variables have a positive effect on ISR; profitability harms ISR. Meanwhile, analysis through independent commissioners shows that independent commissioners are unable to moderate firm size and profitability on ISR. Meanwhile, independent commissioners can moderate leverage on ISR.
Overview Faktor Penentu Nilai Perusahaan
Authors: Agustin Isni , Annisa Arna Asna
Published: March 2022

This research aims to analyze the effect of debt-to-equity ratio, return on asset, and current ratio on firm value as measured by economic value added. This research is quantitative research with use regression analysis. This research used secondary data sourced from the annual report of Islamic commercial banks for 2015–2020. The population in this research was 14 Islamic commercial banks in Indonesia for 2015-2020. The sample selection in this study uses purposive sampling to ensure 11 Islamic commercial banks. The results found that the debt-to-equity ratio has a negative and insignificant effect on firm value, return on assets has a positive and significant effect on firm value. The current ratio has a positive and significant effect on firm value. Meanwhile, Islamic social reporting can moderate the relationship between debt-to-equity ratio and return on assets to firm value but cannot moderate the current ratio and firm value.
Pengaruh dewan pengawas syariah, ukuran perusahaan dan investment account holder terhadap pengungkapan Islamic social reporting dengan profitabilitas sebagai variabel moderating
Authors: Hariyanti Anik , Annisa Arna Asna
Published: March 2022

The study examined the effect of DPS (sharia supervisory board), size, and investment account holder on Islamic social reporting with profitability as moderating variable (a case study of sharia commercial banks registered at OJK 2015-2020). The type of research is quantitative by using moderated regression analysis (MRA) as data analysis and using secondary data in the form panel. Based on the study results, it is shown that partially the DPS (sharia supervisory board), size, investment account holder have positive and significant on Islamic social reporting. Profitability can moderate the effect of size on Islamic social reporting but negatively moderate the DPS (sharia supervisory board) and investment account holder on Islamic social reporting.
Determinan pembiayaan murabahah dengan non-performing financing sebagai variabel moderating
Authors: Nauval Amiratun , Rahman Taufikur
Published: March 2022

This study aims to determine the effect of third-party funds, capital adequacy ratio, and return on assets on murabahah financing with non-performing financing as moderating variables. This type of research is a quantitative research using secondary data. The population in this study amounted to 14 Islamic commercial banks. The sample of this study was determined by the purposive sampling method with the criteria determined by the researcher to obtain 60 samples from 12 Islamic commercial banks in the 2016-2020 period. The results showed that the third-party funds and capital adequacy ratio variables positively and significantly affected murabahah financing. In contrast, the return on assets variable had a positive but not significant effect. The moderated regression analysis (MRA) test shows that the non-performing financing interaction can moderate the effect of third-party funds, capital adequacy ratio, and return on assets on murabahah financing.
Analisis faktor-faktor yang mempengaruhi kinerja keuangan Bank Umum Syariah
Authors: Kurniawan Heri
Published: March 2022

This study aims to examine how much Intellectual Capital, Islamic Corporate Governance, Islamic Social Responsibility, Islamic Ethical Identity, and Zakat can affect Islamic commercial banks' financial performance. The population in this study is Islamic Commercial Banks in Indonesia. The method of determining the sample using the purposive sampling method. The data used is secondary data. Hypothesis testing is done by using multiple regression analysis techniques. The study results indicate that Intellectual Capital and Islamic Ethical Identity affect financial performance. Islamic Corporate Governance does not affect Financial Performance, Islamic Social Responsibility, Islamic Corporate Governance, Islamic Social Responsibility, and Zakat does not affect Financial Performance of Islamic Commercial Banks. Simultaneously, these independent variables have a positive and significant influence on the Financial Performance of Islamic Commercial Banks.
Diversidad alfa de pteridofitas en el bosque siempre verde de tierra bajas de la Reserva Ecológica Cofán Bermejo, Sucumbíos – Ecuador
Authors:   Universidad Estatal Amazónica, Facultad de Ciencias de la vida, Carrera de Biología, Nueva Loja, Ecuador., Guala Paola , Monar Richard ,   Universidad Estatal Amazónica, Facultad de Ciencias de la vida, Carrera de Biología, Nueva Loja, Ecuador., Mestanza-Ramón Carlos ,   Research Group YASUNI-SDC, Escuela Superior Politécnica de Chimborazo, Sede Orellana, El Coca 20001, Ecuador
Published: March 2022

Los helechos son un grupo taxonómico de criptógamas vasculares pertenecientes al reino plantae división de las pteridofitas, estas carecen de flores y semillas. Son de importancia ecológica por que se fijan al suelo otorgando una protección contra la erosión, cumplen funciones muy importantes dentro de los ecosistemas, ya que intervienen en el ciclo del nitrógeno y fósforo por lo tanto pueden actuar como fitorremediadores de la salud de los ecosistemas. En los últimos 10 años no han existido investigaciones sobre las pteridofitas en la Reserva Ecológica Cofán Bermejo y se desconoce su situación actual respecto de su diversidad y estado ecológico. En este contexto, el presente estudio tuvo como objetivo general determinar la diversidad alfa de Pteridofitas en la Reserva Cofán Bermejo, provincia de Sucumbíos, mediante técnicas individuales que permita establecer desafíos en procesos de conservación biológica y 4 objetivos específicos; Diagnosticar la situación actual del área de estudio, mediante entrevistas semiestructuradas de campo, para establecer una línea base. Determinar la riqueza, abundancia y caracterización de las principales especies de Pteridofitas en la Reserva Cofán Bermejo, aplicando los índices de Shannon y Simpson, complementando con la ayuda del repositorio Bioweb. Establecer desafíos en procesos de conservación biológica, utilizando la técnica juicio de expertos para fortalecer la gestión del área protegida y la funcionalidad de sus ecosistemas. Los principales resultados indican que existe una diversidad media y baja de pteridofitas. Finalmente, es necesario centrar esfuerzos para mejorar la gestión de la Reserva Ecológica Cofán Bermejo enfocado en la capacitación del personal que permita contribuir a la conservación de las especies en estudio y disminuir los conflictos internos de la reserva.
Necessity and Feasibility of Logistics Informatization in Ceramic Industry
Authors:   Financial Management Department, Branch of Islamic Azad University, Yazd, Iran., Purnowidodo Anindito , Anam Khairul ,   Financial Management Department, Branch of Islamic Azad University, Yazd, Iran., Wahyudi Ari ,   Financial Management Department, Branch of Islamic Azad University, Yazd, Iran.
Published: March 2022

During past decade, following the increase in the diversity of the patterns of client expectations and its consequent rise of industrial competition for better productions and services, organizations increasingly paved the ground for higher flexibility in production lines and product development to meet the costumers' needs. But managers of many industries learned that in order to survive in the market, improving internal procedures and company's flexibility is not solely enough but material and parts suppliers must also match the company's market development policies. Competitive environment faced companies with several challenges such as reduction of production cycles, decrease in distribution time, decrease in inventories and also waiting time, which are all of high importance to maintain profitability in the market. In order to solve these problems, the process which is now referred to as Supply Chain Management was introduced; meanwhile the notion was soon spread that the real competition was not between companies but was between supply chains indeed and logistic as a part of it was remarked. In the first step, through a critical review of the literature the constituent elements of logistics costs were integrally identified and content classified. The output of this stage developed a model that represents the main structural constituent of logistics costs with associated variables. By using a questionnaire and interviewing elites the general model was then turned into a native model in the ceramic and tile industry. Then based on conceptual cost model, consisting of structures and variables, a case study on Khayyam Ceramic and Tile Company was conducted and using financial statements and interviewing relevant units within the company, a cost framework was extracted and following results were obtained. According to the study, 11% of the total costs of the company accounted for logistics costs of which, 33% was transportation costs , 39% inventory costs, 16% storage and handling costs, and 12% costumer related services and order processing.
The Exploration of the Main Commercialization Modes of Online News Communication
Authors:   University of Journalism and Mass Communication of the Republic of Uzbekistan, Tashkent, Uzbekistan, Seetharama N
Published: March 2022

In the article discussed the mechanism of the process of commercialization of media products and the information model of the internet media as the main element of commercialization is very complex by nature of the news segment of the Internet Media: article technical, form legal, purpose socio-economic. Each of its components is considered to develop a serious supply of information (information-technological, information-analytical), which is the basis of the process of commercialization of media systems. Today, the Internet is a rapidly developing type of media, as well as information and advertising sources. It is also necessary that the company that wants to use Internet opportunities effectively exists in the global network. This also sets new requirements for website creators. The wide use of the internet as a data transmission channel in the implementation of projects makes it possible to reduce the financial costs of the company. Already, the Website is an open resource for residents of the whole world.
Concept of Environmental Protection in Geographical Culture
Authors:   Department of Geography, Namangan state University, Uychi street 160136, Uzbekistan, Samoylenko D
Published: March 2022

During the years of independence, especially in recent years, serious attention has been paid to improving the environmental situation in our country. In particular, Presidential Decree No. PF-5863 “On the approval of the Concept of Environmental Protection of the Republic of Uzbekistan for the period up to 2030” was adopted. Decision No. PP-4477 “On Approval of the Strategy for the Transition of the Republic of Uzbekistan to a Green Economy for the Period of 2019-2030,” Cabinet of Ministers Decision No. 841 on measures to implement national goals and targets for sustainable development until 2030, the implementation of which is directly related to the geographical culture of the individual.
Discussion on Chaos Circulation Schema of Taiji Diagram
Authors:   University of Southern Mindanao, Deshmukh Monal
Published: March 2022

The fusion of China, I like to move the arrow of the dynamic field on the Taiji chart to the heart of one of the following laws of motion, the creation of yin and yang, the movement of metal, wood, water, fire and the earth to give rise to all evolutionary philosophical thoughts. The Taoist inaction WTO emphasizes the unity and contradiction of opposites. Confucius is indeed another gossip about the centrifugal movement, such as arrows, benevolence, justice, etiquette, wisdom, and belief in the birth of Confucianism. They are born to promise the highest degree of ethical adaptation. Unfortunately, they are usually viewed from a macro and micro perspective. Analysis of the problem. I don’t really understand the picture of the voltmeter of Tai Chi Bagua, and there is no way to find the source below, nor does it explain all the real meanings of Taiji Bagua. It cannot play a huge role in science and technology.
A HUMANIZAÇÃO DO PARTO - SUA INFLUÊNCIA NA PRÁTICA DE EPISIOTOMIA SEM INDICAÇÃO CLÍNICA
Authors: Moreira de Sousa Jorge Luiz , Vilanova Araújo Raquel
Published: March 2022

Mesmo com a existência das recomendações, observa-se que no Brasil tem sido frequente o emprego inapropriado da episiotomia, e, portanto das implicações negativas para a mulher como o desconforto físico, riscos de infecção pós-parto, aumento de perdas sanguínea, disfunção sexual e outras. O estudo objetiva saber se a humanização do parto influencia na prática de episiotomia sem indicação. Trata-se de um estudo de revisão integrativa da literatura realizado em seis etapas interligadas: elaboração da pergunta norteadora, busca na literatura, coleta de dados, análise crítica dos estudos incluídos, discussão dos resultados e apresentação da revisão integrativa. Utilizou-se a estratégia PICo, em que P refere-se à população (Gestantes em trabalho de parto); I refere-se ao interesse do estudo (Uso da Episiotomia); C refere-se ao contexto em que o estudo se pauta (Humanização do parto vaginal) e O aplica-se aos resultados (Parto normal sem Episiotomia).  Observa-se que a episiotomia é uma prática inapropriada e prejudicial à saúde da mulher quando não recomendada. É um dos procedimentos cirúrgicos mais utilizados na obstetrícia atual, chegando ao alarmante percentual entre 12,2% a 75%, contrariando a Organização Mundial da Saúde – OMS que preconiza apenas 10% excepcionalmente.  Concluímos que as contribuições da pesquisa visam aprofundar a discussão de que a prática da episiotomia em partos vaginais está absolutamente em desacordo com a OMS, afirmando que devemos adotar medidas de cuidado comprovadas cientificamente. A prática da episiotomia de forma indiscriminada sem indicação clínica configura-se negligencia e desrespeito a mulher, colocando o binômio mãe-filho em situação de risco.
Pengaruh Gaya Mengajar Demonstrasi Terhadap Kemampuan Renang Gaya Punggung
Authors: Tendean Nicky , Makadada Fredrik , Mumekh Mieke
Published: March 2022

Masalah yang yang ditemukan dalam penelitian ini adalah banyak peserta didik pada Saat materi renang tidak beriminat bahkan banyak yang takut untuk mengikuti materi. Banyak hal yang menyebabkan sehingga permsalahan ini muncul seperti, pemilihan metode dari seorang guru yang kurang tepat sehingga para siswa takut untuk mengikuti kegiatan pembelajaran renang. Oleh sebab itu masalah dalam penelitian  ini dapat dirumuskan pada: Apakah terdapat pengaruh metode mengajar demonstrasi terhadap kemampuan renang pada Mahasiswa Jurusan PKL FIK Unima. Metode penelitian yang digunakan adalah metode eksperimen berupa metode mengajar demonstrasi. Dengan hasil analisis penelitian menggunakan uji t observasi dan uji table yang didapat dari derajad kebebasan yaitu 12+12-2 =22 dengan taraf kesalahan 5% maka dapat disimpulan bahwa penelitian tentang Metode mengajar demonstrasi diberikan selama delapan minggu dengan frekuensi tiga kali seminggu dapat meningkatkan kemampuan renang gaya punggung pada Mahasiswa Jurusan PKL FIK Unima.
Pengaruh Daya Ledak Otot Terhadap Kemampuan Mengoper Bola Dalam Permainan Sepakbola
Authors: Rambi Cirsten , Sumarauw Fredrik , Sukadana Bacilius
Published: March 2022

Masalah yang ditemukan saat pelaksanaan observasi adalah kurangnya penguasaan teknik dasar dalam permainan sepak bola terlebih khusus dalam teknik mengoper bola, masih sangat minim pelaksanaanya sehingga melalui itu peneliti merumuskan permasalahan sebagai berikut Apakah terdapat daya ledak otot tungkai terhadap kemampuan mengoper bola dalam permainan sepak bola pada siswa SMA Negeri 1 Modoinding. Pengujian hipotesa penelitian menggunakan teknik statistik Uji t dengan metode eksperimen berdasarkan pemberian perlakuan berupa latihan yang mengarah kedaya ledak otot tungkai. Sedangkan hasil analisis hipotesa diperoleh dari pengolahan data sebelum dan sesudah diberikan perlakuan pada objek. Maka t observasi yang diperoleh dari perhitungan tes observasi dengan menggunakan taraf kesalahan 5% adalah 5,28. Sehingga dapat disimpulkan bahwa daya ledak otot tungkai memberikan pengaruh terhadap kemampuan mengoper bola dalam permainan sepak bola pada siswa SMA Negeri 1 Modoinding.
Pengaruh Metode Bagian Gerak Dasar Forehand Drive Permainan Tenis Meja Mahasiswa Universitas Negeri Manado
Authors: Tangka Aprilyanto , Sungkudon Djoni , Kumenap Eduard
Published: March 2022

Dari hasil pengamatan, banyak mahasiswa Pendidikan Olahraga (POR) Fakultas Ilmu Keolahragaan (FIK) Unima belum bisa melakukan gerak dasar forehand drive dalam permainan tenis meja dengan baik serta benar. Tujuan penelitian mengetahui pengaruh penerapan metode bagian terhadap peningkatan gerak dasar forehand drive dalam permainan tenis meja pada mahasiswa putra POR FIK Unima. Metode yang digunakan yaitu metode eksperimen. Sampel berasal dari mahasiswa POR berjumlah 30 orang diambil secara acak. Rancangan penelitian yaitu“randomized control group pre-test and post test design. Teknik analisa data yaitu analisis statistik uji – t. Hasil pengujian hipotesis penelitian diperoleh thitung senilai 7,102. Berdasarkan tabel distribusi t pada = 0,05  dengan dk  = n1 + n2 – 2 = 15 + 15 – 2 = 28, maka diperoleh nilai t tabel = 2,048. Kesimpulan penelitian ini yaitu terdapat pengaruh penerapan metode bagian terhadap gerak dasar forehand drive dalam permainan tenis meja mahasiswa POR FIK Unima.
Pengaruh Gaya Mengajar Periksa Sendiri Terhadap Kemampuan Menggiring Bola Dalam Permainan Sepak Bola
Authors: Parengkuan Alvaro , Paturusi Achmad , Lomboan Ellen B
Published: March 2022

Masalah dalam penelitian ini adalah kurangnya penguasaan teknik dasar dalam permainan sepak bola terlebih khusus dalam teknik menggiring bola. Hal ini terlihat jelas pada pembelajaran sepak bola banyak pemain yang belum bisa menggiring bola dengan cepat dan luwes sehingga berpengaruh pada gerakan serangan balik kedaerah lawan. Melalui itu peneliti merumuskan permasalahan sebagai berikut: Apakah terdapat pengaruh gaya mengajar periksa sendiri terhadap kemampuan menggiring bola dalam permainan sepak bola pada mahasiswa Jurusan PKL FIK Unima? Pengujian hipotesa penelitian menggunakan teknik statistik Uji t dengan metode eksperimen. Populasi dan Sampel adalah mahasiswa putra semester IV Jurusan PKL FIK Unima yang berjumlah 24 orang. Instrumen penelitian yang digunakan adalah tes menggiring bola sedangkan Hasil analisis hipotesa yang diperoleh dari pengolahan data sebelum dan sesudah diberikan perlakuan pada objek adalah senilai 5,33 dari taraf kesalahan 5%. Maka didapat kesimpulan penerapan gaya mengajar periksa sendiri memberikan pengaruh terhadap kemampuan menggiring bola dalam permainan sepak bola.
Models of use of technology in elementary schools at Kosovo
Authors: Kryeziu Veli , Avdiu-Kryeziu Shqipe
Published: March 2022

There is relatively little research on the use of technology in contemporary teaching in our schools, therefore it is very important to explore this topic and to produce realistic results that reflect the use of technology in teaching in elementary schools in Kosovo. The topic of this research is going to be studied in terms of theory as well as in terms of practice. Regarding the theoretical aspect, various literature related to this issue will be analyzed and explored, respectively with the elementary school planning, the use of technology in teaching, curricula, laws, administrative instructions and regulations in force, whereas regarding the practical aspect, a special attention will be paid to the use of technology in contemporary teaching in Kosovo elementary schools, by analyzing the findings of the research that will be presented statistically in this study. Particular focus will be given to the use of technology in the curricular area society and environment. The research will be carried out through method, respectively qualitative methods. The teacher interviews will contain 5 questions. This research is expected to define the level of the use of technology in the curricular area society and environment in elementary schools of Kosova.
In silico identification of potential inhibitors from rumex vesicarius against DPP4 of diabetes mellitus
Authors: Davella Rakesh , Reddy V. Ravinder , Pujala Shivakrishna , Burgula Kavitha , Mamidala Estari
Published: March 2022

Given the global epidemic of type-2 diabetes mellitus (T2DM) infection and the lack of suitable therapeutic options for diabetics, only a few medications have been licensed for the treatment of infected patients. Newer anti-diabetic medications with innovative mechanisms of action, as well as ways to reduce attrition in the early stages of drug development, are urgently needed. Rumex vesicarius was tested for antibacterial and antioxidant properties. Hence far, no in silico anti-diabetic study has been published against DPP4, so the goal of this paper is to report on the in silico docking of phytochemicals found in this plant against the target DPP4. On a series of known Rumex vesicaris compounds, in silico anti-T2DM lead prioritization was done. Using Autodock 4, the docking of DPP4 with 12 phytochemical compounds was done. Twelve compounds (Apigenin, Chrysophanol, Emodin, Physcion, Catechin, Epicatechin, Luteolin, quercetin, Rhein, tetramethylene sulfone, alloaromadendrene, and cis-Limonene oxide) were docked into DPP4 in the present study, and one compound, Chrysophanol, showed a high binding score (-8.99 PHE:559 may have a crucial function in the binding of these compounds.
Response of date palm cv.barhi microshoots to salinity stress elevation
Authors: Alasadi Mufeed Daher , Ali Abdulminam H. , Abdel-Wahid Aqil Hadi
Published: March 2022

Salinity is one of the serious and crucial problem facias the plant in this planet. Fortunately, plants have different lines of defending system that help to overcome such environmental stress. This study uses a different NaCl level to investigate the behavior of date palm microshoots at two stages (multiplication and elongation) of micropropagation protocol. Study found the salinity stress effect on multiplied and elongated shoots at high levels of salt 150 and 200mM. At these levels the morphological and physiological aspects are changed in compression with control and other salt treatments (25-100mM). The physiological aspects recorded elevation in the rates of carbohydrate, proline and abscisic acid when NaCl concentration increasing. However, study concluded the salinity may help to improve some morphological aspect like shoot diameter that help to increase the plant survival during acclimation stage.  stage. Concentrations.