bluuebunny/crossref_metadata_2025 huggingface dataset:
The relationship of health knowledge, attitude and implementation of health protocol with incidence of suspected COVID-19 on pregnant mothers at Lendah II Public Health Center
Authors: Indriastuti Ria , Kasjono Heru Subaris , Estiwidani Dwiana
Published: December 2022

Background: A individual who matches one of the clinical criteria for acute fever and cough is suspected of having COVID-19. Fever, cough, weakness, headache, muscle aches, sore throat, runny nose/stuffed nose, shortness of breath, anorexia, nausea, diarrhea, or loss of consciousness are all possible symptoms or patients with severe ARI (Acute Respiratory Infection) who have had a fever (> 38°C) and cough in the last 10 days, or who have had acute anosmia, or who have had acute ageusia without other causes that have gone away.

Objectives: The goal of this study was to see if there was a link between the amount of knowledge, attitudes, and application of health protocols in pregnant women at the Lendah II Health Center and the incidence of suspected covid-19.

 Methods: This cross-sectional survey took place from November 12, 2021, to January 31, 2022. The number of respondents in this study was 80, and the samples were gathered using a purposive sampling technique. The data collection tool employs a questionnaire sheet and the Ag-RDT screening method to examine covid-19 suspected. Univariate data analysis with frequency distribution, bivariate data analysis with chi square test, and multivariate data analysis with logistic regression were employed in this study

Results: According to the bivariate analysis, there was a 0.000 p value relationship between mothers and the results of the covid-19 screening, a 0.031 p value relationship between the mother's attitude and the results of the incidence of suspected covid-19 and a 0.005 p value relationship between the implementation of the health protocol and the results of the incidence of suspected covid-19. With a significance value of 0.000, the results of the multivariate analysis of the independent variables have a joint effect on the assessment of thi incidence of suspected covid-19. Knowledge has a OR value of 0.006, attitude is 0.196, and health-care implementation has a OR value of 0.079.

Conclusions: There were correlation between of the incidence of suspected covid-19 in pregnant women at the Lendah II Health Center are linked to knowledge, attitude, and application of health protocols
The effect of transcutaneous electrical nerve stimulation (TENS) on decreasing primary dysmenorrhea pain in adolescents
Authors: Sholihah Nur Rahmawati , Kumorojati Ratih
Published: December 2022

Background: Dysmenorrhea is medical condition indicated by an increase of the prostaglandin (PG) F2-alpha hormone and cyclooxygenase (COX-2) causing hypertonic as well as vasoconstriction activity to the myometrium. It leads to ischemia and stimulating pain in the uterine organs. The condition influence quality of life and productivity of majority female patients. Dysmenorrhea incidence in Indonesia is reported by 64.25% and a total of 52% of students in Yogyakarta experienced drop activity during menstruation.

Objectives: This study aimed to evaluate the effect of TENS in reducing primary dysmenorrhea pain among female adolescents in General Ahmad Yani University Yogyakarta

Methods: A quasi experiment study with pretest-posttest control group design was conducted. A total of 24 participants for intervention and control group were recruited. In order to recruit study participants, this research implemented a quota sampling approach. Primary dysmenorrhea pain measured using Numerical Rating Scale (NRS) and bivariate analysis between both groups carried out using T-test.

Results: A significant difference (p<0.05) reported from both groups before and after the intervention. Prior to the treatment, the average pain score for intervention group was 6 (1.70) and ranging from 4-10. After the treatment being delivered, the intervention group experienced lower pain intensity by average 3.42 (1.6) between 1-6 score range. Control group in this study reported average pain score before the intervention by 4 (1.16) with and ranging from 3-6. The treatment decreased control group participants pain level to average 1.50 (0.52) between the range of 1-2. TENS is effective for severe pain management. Effleurage massage suitable for moderate level pain management. TENS intervention effective to lower pain by 3.50%.
Conclusions: TENS and massage intervention potential to decrease pain intensity of primary dysmenorrhea. This study reported lower pain level associated with TENS by 3.50%. TENS had significant effect for reducing dysmenorrhea pain by 3.50%.
Syndromic Surveillance Using Structured Telehealth Data: Case Study of the First Wave of COVID-19 in Brazil
Authors: Boaventura Viviane S , Grave Malú , Cerqueira-Silva Thiago , Carreiro Roberto , Pinheiro Adélia , Coutinho Alvaro , Barral Netto Manoel
Published: December 2022

Background

Telehealth has been widely used for new case detection and telemonitoring during the COVID-19 pandemic. It safely provides access to health care services and expands assistance to remote, rural areas and underserved communities in situations of shortage of specialized health professionals. Qualified data are systematically collected by health care workers containing information on suspected cases and can be used as a proxy of disease spread for surveillance purposes. However, the use of this approach for syndromic surveillance has yet to be explored. Besides, the mathematical modeling of epidemics is a well-established field that has been successfully used for tracking the spread of SARS-CoV-2 infection, supporting the decision-making process on diverse aspects of public health response to the COVID-19 pandemic. The response of the current models depends on the quality of input data, particularly the transmission rate, initial conditions, and other parameters present in compartmental models. Telehealth systems may feed numerical models developed to model virus spread in a specific region.

Objective

Herein, we evaluated whether a high-quality data set obtained from a state-based telehealth service could be used to forecast the geographical spread of new cases of COVID-19 and to feed computational models of disease spread.

Methods

We analyzed structured data obtained from a statewide toll-free telehealth service during 4 months following the first notification of COVID-19 in the Bahia state, Brazil. Structured data were collected during teletriage by a health team of medical students supervised by physicians. Data were registered in a responsive web application for planning and surveillance purposes. The data set was designed to quickly identify users, city, residence neighborhood, date, sex, age, and COVID-19–like symptoms. We performed a temporal-spatial comparison of calls reporting COVID-19–like symptoms and notification of COVID-19 cases. The number of calls was used as a proxy of exposed individuals to feed a mathematical model called “susceptible, exposed, infected, recovered, deceased.”

Results

For 181 (43%) out of 417 municipalities of Bahia, the first call to the telehealth service reporting COVID-19–like symptoms preceded the first notification of the disease. The calls preceded, on average, 30 days of the notification of COVID-19 in the municipalities of the state of Bahia, Brazil. Additionally, data obtained by the telehealth service were used to effectively reproduce the spread of COVID-19 in Salvador, the capital of the state, using the “susceptible, exposed, infected, recovered, deceased” model to simulate the spatiotemporal spread of the disease.

Conclusions

Data from telehealth services confer high effectiveness in anticipating new waves of COVID-19 and may help understand the epidemic dynamics.
Use of and Satisfaction With Mobile Health Education During the COVID-19 Pandemic in Thailand: Cross-sectional Study
Authors: Kittipimpanon Kamonrat , Noyudom Angun , Panjatharakul Pawanrat , Visudtibhan Poolsuk Janepanish
Published: December 2022

Background

RamaCovid is a mobile health (mHealth) education system that provides the Thai population with information about COVID-19 and self-risk assessment. RamaCovid has a chatbot system that provides automatic conversations (available 24 hours per day) and a live chat function that allows users to directly communicate with health professionals (available 4 hours per day in the evening). The system consists of (1) COVID-19 vaccine information, (2) self-care after vaccination, (3) frequently asked questions, (4) self-risk assessment, (5) hospital finding, (6) contact number finding, and (7) live chat with a health professional.

Objective

This study investigates the use of and satisfaction with the RamaCovid system.

Methods

Overall, 400 people were recruited via RamaCovid by broadcasting an infographic about the study. Questionnaires collected demographic data, users’ experiences of RamaCovid, and the use of and satisfaction with the system. The questions were answered using a 5-point Likert scale. Descriptive statistics were used to describe the participant characteristics and their use of and satisfaction with the RamaCovid system. The Mann-Whitney U test was performed to examine the difference in use and satisfaction between the adult and older adult groups.

Results

The participants showed high use of and satisfaction with the RamaCovid system. They used the information to take care of themselves and their family, and they gained information about their COVID-19 risk. The users were satisfied with the system because the information was easy to understand, trustworthy, and up to date. However, the older adult group had lower use of and satisfaction with the system compared to the adult group.

Conclusions

RamaCovid is an example of the successful implementation of mHealth education. It was an alternative way to work with the call center during the COVID-19 pandemic and increased access to health information and health care services. Providing ongoing updated information, improving the attractiveness of the media information, and the age group difference are important issues for further system development.
Cultural Adaptation of the Actionable Health App Evaluation in Japan: Protocol for a Web-Based Modified Delphi Expert Consensus Study (Preprint)
Authors: Yokomitsu Kengo , Takashina Hikari N , Takebayashi Yoshitake , Muranaka Seiji
Published: December 2022

BACKGROUND

With an increase in both the number of mental health disorders people are experiencing and the difficulty in accessing mental health care, the demand for accessible mental health care services has increased. The use of mobile devices has allowed people to receive care in their daily lives without restrictions on time or location. However, the majority of publicly available mobile health apps are not evidence-based, and the top-rated apps are not always safe or user-friendly and may not offer clinically beneficial results.

OBJECTIVE

This study aims to create a cultural adaptation of the American Psychiatric Association’s comprehensive app evaluation framework in Japan using a web-based modified Delphi expert consensus.

METHODS

A web-based modified Delphi study includes developing the Japanese version of the comprehensive app evaluation framework and 3 Delphi rounds. In the first round, our working group sends a questionnaire to the panelists, who then complete it. In the second and third rounds, the working group sends a questionnaire and a summary of the panelists’ answers based on each of the previous rounds. The panelists answer the questionnaires based on this summary. The summarization procedure is automated to help reduce the biases that can be generated when panelists’ answers are summarized and when the panelists receive them. The working group sends only the result of the summarization with the next round’s questionnaire. All interactions between the working group and the panelists will be conducted on Qualtrics (Qualtrics Japan LLC), a questionnaire platform. To culturally validate the comprehensive mental health app evaluation framework, participants from the following three categories will be recruited in Japan: (1) researchers, (2) practitioners, and (3) app developers.

RESULTS

This study received funding from a crowdfunding campaign in Japan (April 2023). The Delphi study began in January 2023 and will be completed in December 2023. We had already completed the translation of the 105 original app evaluation item questions by December 2022.

CONCLUSIONS

While the need for treatment using mental health apps is increasing, no framework that can be used to develop a centralized database for health apps is available or accessible, and no consensus has been reached among stakeholders in Japan about an appropriate framework. The results of the web-based modified Delphi method presented in this paper may provide direction for the development and use of mental health apps in the future among the relevant stakeholders. Furthermore, this study will enhance recognition of the framework among researchers, clinicians, mental health app developers, and users, in addition to devising new instruments to help users or practitioners efficiently choose the right app for their situations.

INTERNATIONAL REGISTERED REPORT

PRR1-10.2196/44469
Adolescent Reproductive Health Issues and Sexual Behaviors in Coastal Communities: A Case of Biriwa, Ghana
Authors: Kumi-Takyiwaa Afua
Published: December 2022

Abstract

Adolescence is a vital stage of human development because it is characterized by physical, mental, emotional, and psychological changes and sexual experimentation as an individual transitions from childhood to adulthood. This study investigated adolescent reproductive health issues and sexual behaviors in Biriwa, Ghana. The study draws on the health belief model and social learning theory components to analyze the motivations and responses toward reproductive health issues. The study employed a descriptive survey design, and a questionnaire was used to gather data from 200 adolescents. The study discovered the prevalence of unhealthy premarital sexual intercourse and consequent abortion of pregnancies. Peer pressure and lack of financial support from parents or guardians were the main factors that motivated adolescents to engage in unhealthy premarital sex. Therefore, it is recommended that the health center provide regular reproductive health education for adolescents in the community.

Keywords: Adolescent, Sexual Behaviour, Sex, Reproductive Health 

Abstrak

Masa remaja merupakan tahap vital perkembangan manusia karena ditandai dengan perubahan fisik, mental, emosional, dan psikologis serta eksperimentasi seksual sebagai transisi individu dari masa kanak-kanak menuju dewasa. Penelitian ini menyelidiki masalah kesehatan reproduksi remaja dan perilaku seksual di Biriwa, Ghana. Studi ini mengacu pada komponen model keyakinan kesehatan dan teori pembelajaran sosial untuk menganalisis motivasi dan tanggapan terhadap masalah kesehatan reproduksi. Penelitian ini menggunakan desain survei deskriptif, dan kuesioner digunakan untuk mengumpulkan data dari 200 remaja. Studi ini menemukan prevalensi hubungan seksual pranikah yang tidak sehat dan aborsi kehamilan. Tekanan teman sebaya dan kurangnya dukungan finansial dari orang tua atau wali menjadi faktor utama yang memotivasi remaja untuk melakukan hubungan seks pranikah yang tidak sehat. Oleh karena itu, disarankan agar Puskesmas memberikan pendidikan kesehatan reproduksi secara berkala kepada remaja di masyarakat.

Kata Kunci: Remaja, Perilaku Seksual, Jenis Kelamin, Kesehatan Reproduksi
Mewujudkan Pembangunan Inklusi: Peran Rumah Kebugaran Difabel di Daerah Istimewa Yogyakarta
Authors: Muna Choirul , Arifin Zukhruf , Maulyansyah Rifaldi
Published: December 2022

Abstrak

Banyaknya populasi penyandang disabilitas menjadikan sebagai kelompok yang paling rentan terjerumus dalam kemiskinan. Perlu adanya intervensi secara kolektif agar dapat terpenuhi hak-haknya. Tujuan penelitian ini adalah melihat peran pihak swasta dalam mewujudkan pembangunan inklusi melalui program Rumah Kebugaran Difabel (RKD) di Yogyakarta. Penelitian ini menggunakan pendekatan kualitatif deskriptif dengan teknik penarikan informan menggunakan purposive. Data-data penelitian diperoleh menggunakan teknik wawancara, observasi dan studi dokumentasi. Hasil penelitian menunjukkan bahwa RKD melakukan identifikasi masalah, pengembangan sumber daya manusia, dan beberapa upaya dalam memberi akses kebugaran bagi kaum difabel. Sedangkan peran RKD sendiri ada lima antara lain menjadi wadah kegiatan, menghasilkan profesional messure, memfasilitasi kebutuhan difabel, memfasilitasi dengan pemangku kepentingan, dan memberikan layanan dengan sistem gotong royong.

 

Kata kunci: Inklusif, Pemberdayaan, Pengembangan, Peran, Rumah Kebugaran Difabel

 

Abstract

The large population of people with disabilities makes them the most vulnerable group to fall into poverty. There needs to be a collective intervention in order to fulfill their rights. The purpose of this research is to see the role of the private sector in realizing inclusive development through the Difabel Fitness House (RKD) program in Yogyakarta. This study uses a descriptive qualitative approach with a purposive of informants. The research data were obtained using interview, observation and documentation studies. The results showed that the RKD carried out problem identification, human resource development, and several efforts to provide access to fitness for people with disabilities. While the role of RKD itself is five, namely being a forum for activities, producing professional messengers, facilitating the needs of people with disabilities, facilitating with stakeholders, and providing services with a mutual cooperation system.

 

Keywords: Development, Empowerment, Home Fitness Disability, Inclusive, Role
Peran Pemberdayaan Komunitas Sona Circle Terhadap Integrasi Finansial Kelompok Pengungsi di Inggris
Authors: Mahsyar Sheila Shafira , Nihayati Arina
Published: December 2022

Abstrak

Keberadaan komunitas pengungsi seringkali dipersepsikan sebagai komunitas yang tidak memiliki kemampuan untuk menjamin keberlangsungan hidupnya secara berkelanjutan. Tulisan ini berfokus pada upaya pemberdayaan komunitas pengungsi yang berada di wilayah Inggris melalui keterlibatan organisasi nonprofit yakni Sona Circle sebagai perantara antara pengungsi dan penyedia lapangan kerja. Penelitian ini menggunakan metode studi Pustaka integratif dengan penyampaian naratif. Melalui pemberdayaan komunitas diproyeksikan mampu meningkatkan taraf kesejahteraan hidup pengungsi di Inggris demi mendapatkan kesejahteraan yang berkelanjutan. Dengan menerapkan konsepsi mengenai pengungsi, integrasi finansial pengungsi, pembangunan berkelanjutan dan pemberdayaan komunitas maka peneliti mampu mengemukakan hasil penelitian yakni Sona Circle memberi pengaruh dalam mendorong integrasi finansial pada pengungsi melalui program yang bertujuan untuk menjembatani kesenjangan dengan menginisiasi pelatihan dasar sesuai pekerjaan yang diminati serta memberikan peluang magang dan pemberdayaan potensi untuk komunitas pengungsi demi tercapainya kesejahteraan hidup yang berkelanjutan.

Kata kunci: Pemberdayaan komunitas pengungsi, Integrasi Finansial, Sona Circle

Abstract

The existence of a refugee community is often perceived as a community that cannot sustainably ensure its sustainability. This study proposes an effort to empower the refugee community in the UK through the involvement of a non-profit organization, namely Sona Circle as an intermediary between refugees and job providers. This study uses an integrative literature studies method in narrative way . Through community empowerment, it is projected to be able to improve the living standards of refugees in the UK to obtain sustainable welfare. By applying the concept of refugees, financial integration of refugees, sustainable development, and community empowerment, the researcher can present the results of the study, namely Sona Circle influences encouraging financial integration of refugees through programs that aim to bridge the gap by initiating basic training according to the work they are interested in and provide opportunities internships and empowerment of potential for the refugee community to achieve sustainable welfare.

Keywords: Community Empowerment, Financial Integration, Sona Circle
The High Rate of Traffic Accidents on BR 364 in the Section from Vilhena to Pimenta Bueno
Authors: Silva Marcos Holander da , Souza José Arilson de , Ramos Elder Gomes , Pontes Joelson Agustinho de , Neto Leonardo Severo da Luz
Published: December 2022

The objective of this research was to seek to identify what makes the stretch of Highway BR-364, between the municipalities of Vilhena-RO and Pimenta Bueno-RO, with approximately 174 km, theoretically small in relation to others, have a high rate of road accidents. traffic, where almost half, about 46%, leave people injured. The data presented here were collected from the Federal Highway Police website, the body responsible for attending to and recording incidents on the country's federal highways. With statistical records of the last 10 years (2010-2020), it was found that almost half of the claims were caused by human error, mainly due to the lack of attention of drivers, as soon as they can be avoided, these numbers would be even greater if we consider defects mechanics, among others, as human error in the lack of preventive maintenance on vehicles. An interesting piece of data found in the surveys is that, contrary to popular belief, more than 75% of traffic accidents occurred in a straight line, theoretically in places with better visibility, added to this, lane departures were the most common causes among the 21 listed by the police. With this study, we seek to help authorities with jurisdiction over the road to make decisions in their public prevention policies, which can reduce accident rates and save lives in the near future. lane departures were the most common cause of the 21 listed by the police. With this study, we seek to help authorities with jurisdiction over the road to make decisions in their public prevention policies, which can reduce accident rates and save lives in the near future. lane departures were the most common cause of the 21 listed by the police. With this study, we seek to help authorities with jurisdiction over the road to make decisions in their public prevention policies, which can reduce accident rates and save lives in the near future.
Care with the fixation for the transflight of the pediatric patient in rotary wing aircraft: integrative literature review
Authors: Batista Euseli de Assis , Souza Ana Izabel Jatobá de , Nascimento Keyla Cristina do
Published: December 2022

The objective was to identify the necessary care for the safe fixation during the transflight of the patient from 0 to 14 years old in aeromedical service of rotary wing aircraft. Method: integrative literature review. Data collection took place in the databases: Medical Literature Analysis and Retrieval System Online, Cumulative Index to Nursing and Allied, Scopus, Latin American and Caribbean Literature in Health Sciences, Embase; Nursing Database and Scientific Electronic Library Online, using the Health Sciences and Medical Subject Headings descriptors: “Air ambulance,” “Air medical service,” “Pediatric patient,” “Helitransported,” “Emergency helicopter,” “ Air rescue,” “Pre-hospital emergency care” From June/July 2022. Inclusion criteria: articles available in full in English, Portuguese and Spanish, from 2010 to 2022. Publication in annals, reports were excluded of experience and texts from graduation course completion works. Results: 412 studies were found, after applying the criteria, the final sample comprised four articles, where the thematic categories emerged: characteristics of pediatric scene flights as well as the procedures performed; transport epidemiology and qualification and training of professionals who work in pediatric emergency services. Final considerations: there is a need for production in the literature addressing the fixation of the pediatric patient in the transflight on a rotary wing after the rescue. Information and concern about the transfer of pediatric patients reinforce the importance of training professionals to provide safe care.
Morbimortality in American Cutaneous Leishmaniasis in the Xingú region – Pará: Elaboration of a digital booklet for health professionals
Authors: Guimarães Simony do Socorro de Vilhena , Santos Valéria Regina Cavalcante dos , Nunes Silvia Ferreira , Neto Silvestre Savino , Costa Marilene de Sousa , Chaves Nelma Maria de Lima , Uchôa Thaís Lopes do Amaral , Oliveira Elane Magalhães , Jacinto Regina Racquel dos Santos , Rupf Josiane Macedo de Oliveira , Ribeiro Elidiane de Carvalho , Souza Edioneise Dantas de , Castilho Carla Caroline Motta , Costa Claudeth Freitas da , Cunha Taynnara de Oliveira do Espírito Santo , Peixoto Ivonete Vieira Pereira , Oliveira Tainá Sayuri Onuma de , Guimarães Adriane Wosny , Rodrigues Larissa das Graças Santos , Uchôa Gizelle Rodrigues , Rocha Claudia Aparecida Godoy , Sousa Patrício Macedo de , Moura Blenda Evangelista de , Ferreira Jean Jorge da Silva , Souza Juliana Nava de , Brito Danielle de Sousa Ferreira , Oliveira Iranildo Lopes de , Carneiro Irna Carla do Rosário Souza
Published: December 2022

Objective: To carry out a survey of the morbidity and mortality of American Tegumentary Leishmaniasis (ATL) in the Xingú / PA region. Method: Study with a quantitative and qualitative approach of an exploratory nature and descriptive characterization, starting from the analysis of morbidity and mortality data to the construction of a technology in Health, in the format of a digital booklet, to assist health professionals in the surveillance and assistance to patients with ATL. Results: Professionals oriented on the use of protocols, the need for assisted treatment and patient follow-up until cure, in addition to the need to pay attention to adverse events and the presence of coinfections, thus reducing complications and deaths during treatment. Conclusion: The use of a health technology proves to be of fundamental importance to help the health professional in the care of ACL patients, as it allows quick and easy access to clarify doubts about protocols, flows, references in the state, available medications. The pilot study took place in the Xingú - Pa health region, due to its epidemiological importance, being one of the most important notifiers of ACL in the state, according to SINAN - PA, and with the particularity of being the region with the largest territorial extension of the country, having many patients in remote areas of care. Thus, it is believed that a digital booklet will help professionals by minimizing the risks of complications, aggravation and death of patients undergoing ATL treatment.
Life Values and Civic Identity of High School Students
Authors: Morozova Elena
Published: December 2022

The paper presents the results of a research project implemented in 2020–2021 at the micro level of political analysis in Krasnodar using survey and expert sessions. The interpretation of empirical data was carried out within the theoretical scope of the concepts of civic identity, theories of values and generational theory. Life values of school students are presented as va­lues-ideals and values-goals, and their significance is determined. The paper characterized cognitive, emotional and behavioural levels of civic identity of high school students and revealed the ideal image of a citizen. The school and the Internet are considered as actors of civic socia­lization. Conclusions were drawn about the need to reconsider the social role of young people in a digital society, to form a new view of the factors and mechanisms of intergenerational transmission, to develop and implement a targeted youth policy. Four university students and five high school students participated in all stages of the project, gaining experience in conducting empirical research and presenting the results.
Peter the Great and Kolomenskoye Palace: Archives, Museums, Archaeology
Authors: Baranova Svetlana , Belyaev Leonid
Published: December 2022

This paper reviews the key deliverables of the study and reconstruction of archaeological findings on the site of the tsar's palace in Kolomenskoye village. The palace was built in the 1660s–1680s during the reign of Aleksei Mikhailovich and his son Fyodor by a group of masters, including from Central Europe (Belarus, Lithuania and other countries), with important assigned roles. In 1670–1690s, the future reformer of Russia Peter the Great, yet a child and a young man, visited this place. He knew and loved the estate. As instructed by him, the palace was fortified and renovated in the late 1710s – early 1720s. It existed for about one century, when the empress Catherine the Great had to dismantle it as it was too old. The site excavations were launched in the 1920s, and were conducted from time to time later. The most important works took place in 1935, 1970–1980s and in the 2000s.

In order to analyze the obtained data, it was necessary to collect the reports on these excavations and finds from various repositories. The missing sections were rebuilt, and a database of finds was compiled. All information was transferred to the map system. A 3D reconstruction is underway. Simultaneously, the archival texts and images of the 17th–19th century palace were collected. As a result, we have been able to show that the palace was the most important of the Tsar's summer residences, also designed to be demonstrated to the global community. Its interiors contained ample European objects. The atmosphere of the palace inspired the young Peter the Great to enjoy and adopt the Western culture and architecture.
Development of Denisovan Culture in Altai
Authors: Derevyanko Anatoliy , Kozlikin Maksim , Shun'kov Mihail
Published: December 2022

The cultural and chronological stratum of the Pleistocene deposits in Denisova Cave, Altai, is the most complete and lengthy in North and Central Asia today. The comprehensive research of the stone and bone industries in the Paleolithic cave layers helped to trace the process of local development of the most antique Altai’s people, who lived 300,000 to 30,000 years ago. The layer-by-layer analysis of stone artifacts helped to identify the stages of material culture of the-then cave dwellers. The most ancient archaeological site in the bottom of the Pleistocene stratum formed ca. 300,000-150,000 years ago is classified as Early Middle Paleolithic. The subsequent development of the Middle Paleolithic traditions is reflected by the discoveries from the layers that formed 150,000-50,000 years ago. According to archaeological, paleoanthropological and paleogenetic data, the development of the Middle Paleolithic site of the cave is associated mostly with the Denisovans. The deposits of the Early Upper Paleolithic uncovered bone remains of only that population. Bone needles with eyes, sets of personal jewelry and symbolic artifacts in the cultural and chronological stratum of Denisova Cave dating back to the period 50,000 years ago all testify that one of the earliest Upper Paleolithic cultures in Eurasia was formed in Altai.
International Experience of Sustainable Farming Systems Operation
Authors: Khalishkhova Laura , Guchapsheva Inga , Temrokova Anzhela
Published: December 2022

This paper explores sustainable farming systems without the drawbacks of conventional intensive farming, as well as focuses on the global organic trends, including the international practice of legal regulation and government support of the area in order to adapt them to the national practice. The author reviews the current state of organic farming in the USA and the European Union: the legislative framework, the certification system, the key measures for the shift from conventional to organic farming, and proposes measures driving the growth of the domestic organic market with such key outcomes as more available high-quality groceries, new ways of tackling environmental challenges, and the establishment of a strong platform for sustainable development of rural areas.
Related Rights in the Digital Economy
Authors: Matveev Anton
Published: December 2022

In the early 21st century, intellectual property has become the most crucial intangible asset. In the digital economy and Industry 4.0, the key drivers of intellectual property law will shift from classical institutions to new legal systems. Related rights are perhaps the most fast-paced new institution of intellectual property law. The purpose of this paper is to determine the role that related rights play in the digital economy. Related rights are a flexible and convenient mechanism protecting intangible property included in the digital economy through organizational and financial investments. In the digital economy, the development of related rights is focused within the framework of the so-called new production rights. We believe that such rights are: 1) the right to investment databases; 2) the right of media publishers to use their publications by online news aggregators; 3) the right to inform about sports events (especially in the digital media).
Historical Tables by Vasily Zhukovsky
Authors: Dolgushin Dmitriy
Published: December 2022

This paper explores the little-studied works of V.A. Zhukovsky, namely, his tables for teaching history. Zhukovsky first learned the didactic genre of history tables back in 1810, when, during his self-learning, he relied on the research conducted by D.J. Hubler and Christian von Schlözer. Schlözer’s historical and geographical maps integrated with synchronistic tables, and metho­dological ideas of his father August Ludwig von Schlözer, became a model for Zhukovsky that steered him in his didactics study. The peak of Zhukovsky's teaching was the period of his service at the court. At that time, he developed a special teaching system using tables with special mnemonic signs. Zhukovsky failed to complete his system and tried to return to it just before his death, when he was busy with the Initial Training Course for his children. In this textbook, the signs created by Zhukovsky were used not only to link the event with the date, but also to encrypt the narrative text. Deciphering it back into the narrative by students was the core of Zhukovsky's didactic plan.
Monkeypox Disease: History, Epidemiology, Threat Assessment, and Management Strategies
Authors: Nath Nikhil , Dhama Kuldeep , Emran Talha Bin
Published: December 2022

Infection with the monkeypox virus is more prevalent among genus Funisciurus squirrels, less prevalent among genus Heliosurus squirrels, and rare among forest monkeys. These squirrels inhabit secondary woods close to human settlements in rural Zaire, particularly where oil palm is cultivated. In Prime Rain Forest, they are in short supply. The monkeypox virus often affects children between the ages of 5 and 9, particularly in rural settings where children hunt and consume squirrels and other small animals. Animal husbandry will minimize the danger and occurrence of human monkeypox, even in areas where the virus has spread to squirrels, as the human population grows and relies primarily on animals for animal protein. Population expansion and economic development in West and Central Africa may lessen the danger of monkeypox infection in people, but visitors who interact with animals should be vaccinated against smallpox. The spread of monkeypox can be stopped by measures such as post-exposure vaccination, contact tracing, case identification, and isolation of infectious patients. The recent monkeypox incidence is of further concern in light of the current COVID-19 pandemic.
Investigative Study of Economic Crisis in Sri Lanka
Authors: Waghmode Pratik Someshwar
Published: December 2022

Abstract: This paper analyses the reasons and scenario of the current economic crisis in Sri Lanka. The study examines the possible reasons for the crisis, its ongoing impact on GDP, tourism industry, and on Sri Lankan rupee against other major currencies in the world. The paper shows that Forex reserves of Sri Lanka mainly depend on Tourism revenue, thus underscoring the importance of the tourism industry. But due to current circumstances of the Covid-19 and its severe impacts leads to a high decline in tourism revenue which ultimately affects the country’s reserves. This resulted in the high depreciation in the value of the Sri Lankan rupee against other major currencies in the world. To assess if the country has enough reserves, we have used the Guidotti - Greenspan rule and we found that since the Covid pandemic has begun, Sri Lanka has been unable to follow this rule and the ratio of reserves to short term debt is continuously decreasing. The external sector of Sri Lanka is also not performing well due to the sharp decline in exports. The IMF has approved a bailout package through its Special Drawing Rights to get over this crisis. Therefore, appropriate actions must be undertaken to overcome the crisis and revive the economy
Timetable Scheduling using Bipartite Graph
Authors: N Buvaneswari , S Rekha
Published: December 2022

Abstract: In any educational institution, the two most common academic scheduling problems are course timetabling and exam timetabling. A schedule is desirablewhich combines resources like teachers, subjects, students, classrooms in a way to avoid conflicts satisfying various essential and preferential constraints. The timetable scheduling problem is known to be NP Complete but the corresponding optimization problem is NP Hard. This problem is solved using bipartite graph. Hence a heuristic approach ispreferred to find a nearest optimal solution within reasonable running time
Deslocamento para trabalho e diferenciais salariais na Região Metropolitana de São Paulo
Authors: Lameira Verônica de Castro , Golgher André Braz
Published: December 2022

O objetivo deste estudo é investigar o diferencial salarial associado à pendularidade na Região Metropolitana de São Paulo com base nos dados do Censo Demográfico de 2010. O foco é averiguar a existência de prêmio salarial para trabalhadores cujos municípios de residência e atividades laborais são distintos, utilizando como controle características individuais, ocupacionais e do município de residência, vis-à-vis trabalhadores que não pendulam e desconsiderando trabalhadores cujos deslocamentos são circunscritos a um mesmo município. Para alcançar esse objetivo, foram usados modelos quantílicos e hierárquicos. Os principais resultados revelam a importância da raça, da instrução e da posição na ocupação para explicar os rendimentos dos trabalhadores ao longo das distribuições de salário de homens e de mulheres. As evidências empíricas sugerem, ainda, uma relação positiva entre deslocamento pendular e rendimento-hora no trabalho principal dos trabalhadores de ambos os sexos. Diferenciais de custo de vida municipais também foram associados com os rendimentos de trabalhadores.
Determinación de timol y carvacrol en una matriz orgánica de alimento para cerdo utilizando Headspace SPME-GC-MS
Authors: Lona-Ramírez Fernando Jonathan , Hernández-López Nancy Lizeth , González-Alatorre Guillermo , Flores-Flores Teresa Del Carmen , Patiño-Herrera Rosalba , Louvier-Hernández José Francisco
Published: December 2022

In recent years, oregano essential oil has been used as an animal food additive due to its antifungal and antibacterial properties as well as s synthetic antibiotic substitute. It is desirable to develop fast and effective thymol and carvacrol quantification method in a swine feed organic matrix. In this work, a performance comparison between the Soxhlet solvent extraction technique using petroleum ether and ethyl acetate and the head space-solid phase microextraction (HS-SPME) technique is made. A 24 design of experiments is performed for defining HS-SPME parameters: equilibrium temperature of 40 ºC, extraction temperature of 40 ºC, ionic strength of 0.57 M, and extraction time of 40 min. The HS-SPME method is more efficient for extracting thymol and carvacrol extraction from an organic matrix. Limits of detection and quantification values using Soxhlet extraction with ethyl acetate were 3.7 and 12.5 μL-1 for thymol and 1.4 and 4.7 μg L-1 for carvacrol, respectively; while LOD and LOQ for HS-SPME were 0.9 and 3.1 μg L-1 for thymol and 0.6 and 1.9 μg L-1 for carvacrol, respectively. The head space-solid phase microextraction method has the potential for quality control in the industry for active compounds present in oregano’s essential oil as an additive into an organic matrix.
Efecto de la consanguinidad y selección sobre los componentes de un índice productivo, en ratones bajo apareamiento estrecho
Authors: Hernández López Dulce Janet , Ulloa Arvizu Raúl , Vázquez Peláez Carlos Gustavo , Tapia Pérez Graciela Guadalupe
Published: December 2022

Con objeto de examinar la influencia de la depresión endogámica en algunas características productivas del ratón de laboratorio, se reanalizaron 871 registros provenientes de 20 generaciones en una línea con cruza consanguínea estrecha con selección a un índice productivo (CNHS) comparando con una línea sin selección, con cruzamiento endogámico (n= 135). Se calcularon los coeficientes de endogamia (F) para cada generación. En todos los componentes del índice (vida reproductiva, estros postparto fértiles y tamaño de camada), se compararon las dos líneas, en las 15 generaciones disponibles de la no seleccionada, por método de mínimos cuadrados, agrupando cada cinco generaciones. La seleccionada, se analizó en las 20 generaciones, para diferencias intergeneracionales con el mismo método. La depresión endogámica se estimó en todas las generaciones con una regresión lineal de consanguinidad (expresada en 10 %) en todos los componentes. Se observó diferencia significativa (P<0.01) entre líneas en las variables analizadas. Los estros post parto fértiles de la línea seleccionada se mantuvieron constantes, hubo un decremento de 0.331 en la no seleccionada (P<0.01). El índice productivo se mantuvo estable (aumentó 0.071) en la seleccionada, en la no seleccionada disminuyó (0.39) hasta desaparecer (G15). La depresión endogámica impactó en la vida reproductiva de ambas, decreció 4.741 días en la seleccionada vs. 7.718 días en la no seleccionada (P<0.01). En la no seleccionada afectó en mortalidad al destete y ciclo estral, la selección al índice contrarrestó ese impacto, probablemente debido a la selección de genes que favorecen el desarrollo gonadal de los ratones.
Identificación de genes candidatos y SNP relacionados con el temperamento del ganado utilizando un análisis GWAS junto con un análisis de redes interactuantes
Authors: Paredes-Sánchez Francisco Alejandro , Sifuentes-Rincón Ana María , Lara-Ramírez Edgar Eduardo , Casas Eduardo , Rodríguez-Almeida Felipe Alonso , Herrera-Mayorga Elsa Verónica , Randel Ronald D.
Published: December 2022

The objective of this study was to identify in Angus and Brangus breed animals with extreme temperament, measured as exit velocity, genomic regions and candidate genes associated with bovine temperament. The population was genotyped with the Genomic Profiler HD 150K chip and after the genome-wide association analysis, the SNPs rs133956611 (P=2.65 E-06) and rs81144933 (P=9.58 E-06) were associated with temperament. The mapping analysis of the regions close to the SNP rs81144933 identified the SNCA (alpha-synuclein) and MMRN1 (multimerin-1) genes at 222.8 and 435.9 Kb downstream respectively, while for the rs133956611 loci the gene GPRIN3 (GPRIN family-member-3) was identified at 245.7 Kb upstream, all three genes are located on the BTA6 chromosome. The analysis of SNCA protein-protein interactions allowed the identification of the genes APP (β-amyloid precursor protein), PARK7 (parkinsonism-associated-deglycase), UCHL1 (ubiquitin-C-terminal-hydrolase-L1), PARK2 (parkin-RBR- E3-ubiquitin-protein-ligase), and genes of the SLC family as candidates to be associated with bovine temperament. All these candidate genes and their interacting were resequenced, which allowed the discovery of new SNPs in the SNCA and APP genes. Of these, the SNPs located in introns 5, 8 and 11 of the APP gene affect splicing site motifs. These results indicate that SNCA and its interacting genes are candidates to be related to bovine temperament.
Concentraciones del factor de crecimiento similar a la insulina 1 (IGF-1) en el líquido sinovial de caballos sanos y osteoartríticos, y su correlación con las citoquinas proinflamatorias IL-6 y TNF
Authors: García-Lacy F. Fernando , Méndez-Cruz Sara Teresa , Reyes-Vivas Horacio , Dávila-Borja Víctor Manuel , Barrera-Morales José Alejandro , Gutiérrez-Ospina Gabriel , Gómez-Chavarín Margarita , Trigo-Tavera Francisco José
Published: December 2022

Insulin-like growth factor I (IGF-1) is the most important known growth factor for cartilage repair in horses. It promotes mitosis of chondrocytes, collagen II expression, and extra cellular matrix production. Osteoarthritis (OA) is the most common musculoskeletal condition that causes lameness and poor performance in sport horses. A total of 11 lame horses were clinically and radiographically evaluated, and all were confirmed to suffer a front metacarpophalangeal lameness by a positive flexion test, a low-4-point nerve block and an intraarticular block. Total protein, IGF-1, IL-6 and TNFa were determined by ELISA, demonstrating changes and different correlations between clinical condition, radiographic changes and degree of inflammation. All horses with joint associated pain and therefore associated lameness, demonstrated a significant increase of total protein (P<0.0001) and IGF-1 concentration (P<0.05). Concentrations of IL-6 and TNFa between controls and lame horses demonstrated significant differences (P<0.01 and P<0.001 respectively). Horses with less radiographic changes, demonstrated the highest IGF-1 expression in synovial fluid, and horses with more chronic OA conditions had very similar IGF-1 expression levels than control joints. In all lame joints, it was identified by Western blot a lighter isoform of IGF-1 (~7.5 kDa) which was inflammation related and it is the molecular weight of the mature peptide, and all control joints expressed a heavier isoform (~12 kDa). This finding could lead to new research for sequencing and targeting the isoform which is not expressed during an inflammatory process within a joint, and to have a better understanding of its role in the horse’s joint.
Uso de células estromales mesenquimales derivadas de la gelatina de Wharton para el tratamiento de uveítis recurrente equina: estudio piloto
Authors: Masri-Daba María , Camacho-Flores Montserrat Erandi , Gómez-Romero Ninnet , Basurto Alcántara Francisco Javier
Published: December 2022

La uveítis recurrente equina (URE) es una enfermedad que afecta del 2 al 25 % de los equinos a nivel mundial, de los cuales el 56 % se quedan ciegos; por lo tanto, es considerada la causa más común de ceguera en caballos. La URE es un padecimiento espontáneo inmunomediado caracterizado por eventos recurrentes de inflamación intraocular. Actualmente, no existe tratamiento para los caballos con esta enfermedad. Las células estromales mesenquimales (CEM) derivadas de diversos tejidos, como la gelatina de Wharton (GW), han demostrado su capacidad de modular la respuesta inmune al regular negativamente el proceso inflamatorio. El objetivo del presente estudio piloto fue el evaluar el efecto del uso de CEM derivadas de GW como tratamiento para la URE. La GW se obtuvo y procesó con base en metodologías previamente descritas para la obtención de CEM. Los caballos involucrados en este estudio recibieron una dosis de 5x106 CEM en la zona subpalpebral. Se evaluó la concentración de interleucinas (IL) (IL-1a, IL-2, IL-10, IFN-g y TNFa) en muestras de lágrima obtenidas antes de la inoculación del tratamiento, 30 min después y 7 días post inoculación. No se observaron cambios significativos en la concentración de IL que sugieran la disminución de IL proinflamatorias. Sin embargo, los caballos con URE tratados con CEM mostraron una respuesta positiva a la terapia, evidenciada por la disminución en la signología de la URE. Los resultados obtenidos sugieren que el tratamiento de la URE con CEM derivadas de GW es una alternativa segura con resultados prometedores.