bluuebunny/crossref_metadata_2025 huggingface dataset:
A Long-term Interpretation of the Effect of COVID-19 on Food Security: A Lesson for the Future Pandemic Diseases
Authors: Sadeghi Malihe , Mohammadi Elahe , Ghods Elahe , As’habi Atefeh
Published: April 2024

Background: The global spread of coronavirus disease (COVID-19) could trigger a food security crisis affecting not only impoverished individuals but also urban residents in low- and middle-income countries. Objectives: Given that various strains of COVID-19 impact food security differently, we assessed the food security status of households in Semnan province, Iran, during and after the containment of the omicron variant. Methods: Data from 231 households were gathered using a standard questionnaire that evaluated socioeconomic characteristics, food security based on the U.S. Household Food Security Survey Module, and vulnerability to food insecurity. A quantitative model was utilized to identify factors associated with food insecurity during and post-pandemic. Results: The findings indicated an improvement in household food security following the management of COVID-19, with significant differences observed in food security levels, especially concerning severe food insecurity, during versus after the COVID-19 period. The quantitative model analysis revealed that, with the exception of the head of household's occupation status, personal savings, and the number of educated and employed members within a household, all variables significantly correlated with food security (P < 0.05). Conclusions: These outcomes highlight how the relationship between socioeconomic factors and food security levels may vary depending on the pandemic's timing, environmental conditions, and household resilience, underlining the importance of adaptive policymaking that responds to current circumstances and the evolving links between socioeconomic determinants and food security.
History of the development of non-state higher education after the implementation of the policy of reform and opening in China
Authors: Шао Б.
Published: April 2024

являясь важной частью системы высшего образования, частные учебные заведения внесли важный вклад в популяризацию высшего образования в Китае и удовлетворение потребностей людей в высшем образовании на разных уровнях. С момента реализации политики реформы и открытости негосударственное высшее образование в Китае прошло три периода развития: период исследования, период активного развития и период совершенствования. Оно становится важной частью высшего образования Китая и играет важную роль в увеличении предложения образовательных услуги и обеспечении равенства. Целью исследования является описание процесса его развития и выявление их особенности.

as an important part of the higher education system, private educational institutions have made important contributions to popularizing higher education in China and meeting people's higher education needs at various levels. Since the implementation of the reform and opening up policy, private higher education in China has gone through three periods of development: the period of exploration, the period of active development and the period of improvement. It is becoming an important part of higher education in China and plays an important role in increasing the supply of educational services and ensuring equality. The purpose of the study is to describe the process of its development and identify their features.
Organization of physical education classes for pupils with metabolic disorders and increased body weight
Authors: Романова С.В. , Еремчук В.Ю.
Published: April 2024

в статье рассмотрены наиболее значимые аспекты организации занятий физической культурой для учащихся средней школы, имеющих нарушения обмена веществ и повышенную массу тела. Авторами обозначена актуальность и значимость темы исследования. Дана краткая характеристика проблемы избыточной массы тела. Уточнена роль физической культуры для направленного решения данной проблемы, включая профилактические цели. Проанализированы основные критерии отнесения их к этой категории и основные задачи коррекционно-компенсаторной и лечебно-оздоровительной работы с ними на уроках физкультуры. Подчеркнута актуальность их овладения навыками самоконтроля и безопасности, а также ведения «Дневников здоровья». Дана краткая характеристика программы внеурочных занятий для детей, имеющих нарушения обмена веществ и повышенную массу тела. Данная программа первоочередно ориентирована на развитие выносливости и силы, так как в совокупности именно эти качества способствуют коррекции телосложения. Дополнительно делается акцент на необходимости обязательных рекомендаций для самостоятельной работы педагогом, включая комплексы для утренней гимнастики, упражнения для корригирования индивидуальных особенностей телосложения. Резюмированы актуальные особенности организации занятий в отношении детей и подростков с избыточным весом.

the article discusses the most significant aspects of organizing physical education classes for secondary school students with metabolic disorders and increased body weight. The authors indicate the relevance and significance of the research topic. A brief description of the problem of excess body weight is given. The role of physical education for a targeted solution to this problem, including preventive purposes, has been clarified. The main criteria for classifying them into this category and the main tasks of correctional-compensatory and therapeutic work with them in physical education lessons are analyzed. The relevance of their mastering the skills of self-control and safety, as well as maintaining “Health Diaries” is emphasized. A brief description of the program of extracurricular activities for children with metabolic disorders and increased body weight is given. This program is primarily focused on developing endurance and strength, since together these qualities contribute to the correction of the physique. Additionally, emphasis is placed on the need for mandatory recommendations for independent work as a teacher, including complexes for morning exercises, exercises for correcting individual physique characteristics. The current features of organizing classes for overweight children and adolescents are summarized.
The effect of physical activity on the cognitive functions of a mature person
Authors: Комарова И.Г. , Гончарук С.В. , Гончарук Я.А. , Амурская О.В.
Published: April 2024

данное исследование направлено на изучение влияния физической активности на когнитивные функции у людей зрелого возраста. В работе были проведены анализ научных статей и исследований. Исследования показывают, что разнообразные виды физической активности могут положительно влиять на когнитивные функции человека зрелого возраста, а именно на его память, речь и интеллект. Важно отметить, что интенсивность и регулярность физической активности имеют решающее значение. Физическая активность при данной проблеме улучшает кровообращение, обеспечивает передачу кислорода и питательных веществ к мозгу; упражнения, направленные на укрепление мышц, способствуют обработке информации и принятию решений; снижению уровня стресса и тревоги, а также улучшению концентрации и внимания.

this study is aimed at studying the effect of physical activity on cognitive functions in older people. The analysis of scientific articles and research was carried out in the work. Research shows that various types of physical activity can positively affect the cognitive functions of a mature person, namely his memory, speech and intelligence. It is important to note that the intensity and regularity of physical activity are crucial. Physical activity in this problem improves blood circulation, ensures the transfer of oxygen and nutrients to the brain; exercises aimed at strengthening muscles, promote information processing and decision-making; reduce stress and anxiety, as well as improve concentration and attention.
Comparative analysis of the activity of the autonomic nervous system by orthostatic and clinostatic tests at the beginning and end of the academic year for Russian and foreign students
Authors: Шаренкова Л.А. , Репицкая М.Н. , Смолина В.С. , Горянная Н.А.
Published: April 2024

обучение в университетах и институтах является интенсивной работой для любого человека. Особенно большие учебные нагрузки испытывают студенты-медики. Обучение в медицинском вузе обладает рядом особенностей, отличающих его от других: насыщенность программы, необходимость передвижения между клиническими базами, которые могут находиться в разных районах города, необходимость обработки большого количества визуальной, слуховой, тактильной и другой информации. Все это требует большого напряжения в работе высшей нервной деятельности, что со временем может вызывать снижение работоспособности. Данные негативные факторы отрицательно влияют на здоровье и общее самочувствие студентов. Нами было обследовано 364 студента-медика 2-х и 3-х курсов. В результате исследования выяснили, что русские девушки и юноши имеют более благоприятные показатели по ортостатической пробе к началу летней сессии, чем иностранные студенты, как юноши, так и девушки.

studying at universities and institutes is an intensive job for anyone. Medical students are experiencing particularly heavy academic loads. Studying at a medical university has a number of features that distinguish it from others: the saturation of the program, the need to move between clinical bases that may be located in different areas of the city, the need to process a large amount of visual, auditory, tactile and other information. All this requires a lot of stress in the work of higher nervous activity, which over time can cause a decrease in performance. These negative factors negatively affect the health and general well-being of students. We examined 364 medical students of the 2nd and 3rd courses. As a result of the study, it was found that Russian girls and boys have more favorable indicators for an orthostatic test by the beginning of the summer session than foreign students, both boys and girls.
Connectivity and Application of the Principle of Multiple Intelligences in the Three Domains of Learning Mathematics
Authors: Vivian Maanu  , Francis Ohene Boateng  , Ebenezer Appiagyei  , Hatsu Edo  , Klu kwasi Theophilus
Published: April 2024

The study aimed to examine how Gardner's Multiple Intelligences applied to Ghana's Senior High School's core mathematics curriculum and instruction. The Core Mathematics curriculum was the primary document reviewed for the study. The action verbs used in the objective, section teacher-learner activities section, and the evaluation section of the core mathematics syllabus were identified and grouped with respect to the multiple intelligences. The analysis revealed that the mathematics curriculum was linked to several intelligences, although some intelligence was underserved. The Senior High School Mathematics Curriculum fails to consider diverse learning styles and preferences. It should provide a diverse range of topics using various instructional techniques. However, children with different intelligences should not experience mathematics as a hindrance. A re-evaluation is necessary to address these issues.
Approximation of BPS Skyrme model using modified Lagrangian Skyrmion
Authors: Oktaviana Aditya Tri , Rahman Alfarasyi Abdul , Gia Huy Truong , Fahmi Khazali
Published: April 2024

One of the nuclear atomic models represented by Skyrmion was the Skyrme model. This model was a modified nonlinear sigma model with a Skyrme field where the classical solution use generalized sixth order terms and potential terms. The binding energy that will be studied in the Skyrme SU(2) model is to generalize the second order nonlinear sigma model terms with sixth order derivative terms. The Lagrangian will be obtained for these two terms to find the BPS (Bogomolny Prasad Sommerfield) solution for the profile function numerically. The result of numerical calculation will be used to calculate static energy and rotational energy, where the characteristic of the nucleus can be observed from these two energies. Furthermore, the value of the coupling constant in the Lagrangian Skyrmion will be calculated from the static energy and rotational energy obtained previously. These values are expected to help in the application of Skyrme model for many research physics field.
Mathematical Models of Biological Control of Dengue
Authors: Kumar Nand Kishor , Yadav Dipendra Prasad
Published: April 2024

Dengue fever, transmitted by Aedes mosquitoes, poses a significant public health threat in tropical and subtropical regions worldwide. Despite efforts to control its spread through various means, including vector control strategies and vaccine development, dengue remains a formidable challenge. Mathematical modeling has emerged as a valuable tool in understanding the complex dynamics of dengue transmission and evaluating control strategies, particularly those involving biological control methods.
Սարաջևաներ / Sarajevas
Authors: Harutyunyan Gayane
Published: April 2024

The author Gayane Mnatsakan Harutyunyan studied in the class of Natalya Popova-Sarajeva, then she did her post-graduate studies under Kira Sarajeva at the Gnesin Russian Music Academy in Moscow and presents her memoirs in her article "Three Generations of the Sarajeva Harpists". The author focuses not only on their performing art, but also on their pedagogical activities, teaching and methodology. The author shares her memoirs and appreciates their role in Armenian art and culture. She mentions the world-famous Armenian composer Aram Khachatryan s approach to harp art, who, among his symphony used harp, ballet and solo works. As an example she mention A. Khachatryan's symphonic poem "Ode to Joy", which holds a significant place in Khachatryan's musical legacy. This piece was composed for an ensemble of violinists, a choir, a symphony orchestra, soloists and 12 harps.
Okul yöneticilerinin Yaşam Boyu Öğrenme Eğilimleri ile Dijital Okuryazarlık Düzeylerinin İncelenmesi
Authors: Alpsülün Mustafa , Balıkçı Hasan Celal
Published: April 2024

Bu çalışmanın amacı okul yöneticilerinin dijital okuryazarlık ve yaşam boyu öğrenme eğilimleri arasındaki ilişkinin incelenmesidir. Çalışmanın örneklemini Şanlıurfa'nın Siverek ilçesinde görev yapan 228 okul yöneticisi oluşturmaktadır. Betimsel tarama yöntemi kullanılarak gerçekleştirilen bu çalışmada, kolay ulaşılabilir örneklem yöntemiyle veriler toplanmıştır. Bulgular incelendiğinde ise; kadınların lehine anlamlı bir yaşam boyu öğrenme eğilimi bulunmuştur. Ayrıca, okul yöneticilerinin dijital okuryazarlık düzeyleri ile boyu öğrenme eğilimleri arasında doğrusal yönde pozitif bir ilişki belirlenmiştir. Bu bulgular, okul yöneticilerinin Dijital okuryazarlık düzeyleri ile boyu öğrenme eğilimleri arasındaki ilişkinin değerlendirilmesine ve eğitim politikalarının geliştirilmesine katkı sağlamaktadır.
Methodology of quantum-chemical calculations
Authors: Bolocan Natalia , Balan Iolanta , Duca Gheorghe
Published: April 2024

This paper emphasizes the importance and complexity of quantum- chemical calculation in theoretical chemistry. Specialized quantum-chemical software, such as Gaussian09, GAMESS, and ORCA, are essential for the analysis of various properties such as geometric and electronic structures, thermochemistry, transition states, and others. The need to have access to appropriate software and computational resources, as well as an understanding of the theory of computational chemistry, is emphasized. Molecular system preparation, geometry optimization, identification of transition states, and analysis of electronic structure and molecular properties are discussed. This methodology will serve as a valuable resource for young researchers, providing a detailed insight into the application of computational chemistry methods in research.
Theories of electron and proton transfer and the need for their development
Authors: Duca Gheorghe , Gorbachev Mikhail Yu.
Published: April 2024

This chapter provides a detailed overview of the evolution of electron and proton transfer research. Significant contributions include Libby's 1952 model, for which R.A. Marcus, provided a solution to the problem of energy conservation in this model by proposing that energy levels can adjust through environmental fluctuations. Henry Taube, made essential contributions highlighting the differences between rigid and labile transition metal complexes in redox reactions. The mechanism of the synchronous transfer of an electron and a proton is also addressed, a consequence of the Frank-Condon principle, which limits the number of electrons transferred simultaneously. The existence of synchronous two-electron transfer processes and their importance in enzymatic reactions are mentioned.Special emphasis is placed on compounds with unusual reactivity and the possibility of synchronous multi-electron transfers. Supramolecular systems and the different applicability of theoretical models in this field are also highlighted. The chapter mentions international nanomachine competitions, where supramolecular systems are used in competitive events, thus emphasizing the practical relevance and continuous innovation in this field of study.
Modeling of the immune response to the viral load: minimum model
Authors: Ialtychenko Olga , Gorinchoy Natalia , Duca Gheorghe
Published: April 2024

A model of the kinetics of the body's immune response to viral load is proposed. The model considers both cellular and humoral components of the immune response. The interaction of T and B lymphocytes is analyzed, as well as the effect of delaying the formation of antibodies. The numerical study of the model system with some values of the model parameters showed the possibility of implementing three main types of possible behaviors: 1) Uncontrolled increase of antigen and critical decrease of T lymphocytes (unfavorable prognosis); 2) Dynamic balance between antigen and T lymphocytes (satisfactory prognosis); 3) Rapid reduction of antigen and stabilization of immune cells (favorable prognosis).
Structural properties and interaction mechanisms of some macromolecules with antioxidant activity studied by the small angle scattering method
Authors: Cazacu Lilia
Published: April 2024

Studying the structural properties and associative interactions of bioactive components such as protein molecules is of particular interest for expanding the spectrum of industrial applications or optimizing existing ones. Thus, the purpose of this research is to study the structure of some proteins with antioxidant activity such as lactoferrin, glucooxidase, β-lactoglobulin, using the X-ray/neutron small angle scattering method.
Mechanisms and kinetics of chemical self-purification of natural waters, using the theory of redox processes
Authors: Bunduchi Elena , Duca Gheorghe
Published: April 2024

The paper describes the mechanisms of catalytic redox processes that take place in natural waters, essential for chemical self-purification processes. The types of redox mechanisms involving both partial charge transfer compounds, free radicals, and reductants, all found in natural waters, are examined. The focus is on redox processes, catalyzed by ions or complex compounds of transition metals, including copper, iron and manganese. These processes involve the main oxidative agents in natural waters: oxygen (O2), hydrogen peroxide (H2O2) and hydroxyl radicals (•OH).
Modeling of water self-purification processes in the presence of group "B" vitamins
Authors: Blonschi Vladislav , Gladchi Viorica , Lis Angela , Culea Maria
Published: April 2024

The paper presents the experimental data regarding the modeling of the chemical processes of water self-purification in the presence of vitamins of the B group: B6, B9 and B12. The results of the kinetic study of redox-catalytic and photochemical processes with the participation of vitamin B6 indicate its faster oxidation with dissolved oxygen. Vitamin B9 does not oxidize through redox processes, but following photolysis, the vitamin generates hydrogen peroxide, which positively influences radical self-purification processes.
Homogeneous catalytic oxidation of medicinal drugs in aqueous model systems
Authors: Mocanu Larisa , Gonta Maria , Matveevici Vera
Published: April 2024

The application of AOPs is an effective alternative for the reduction or elimination of emerging pollutants from residual effluents of pharmaceutical origin. According to European health regulations, pharmaceutical preparations must be completely absent from drinking water and water bodies. As a result, the reduction of emerging pollutants (PE) by applying Fenton and Fenton/UV oxidation was studied according to different physicochemical parameters in the presence of surfactants. The scientific results present the study of the kinetic legitimacy of the advanced oxidation processes of simple systems containing amoxicillin, cephalexin, diclofenac sodium, as well as mixed systems amoxicillin : cephalexin : diclofenac sodium, in the presence of surfactants, through homogeneous catalytic oxidation: a) without sources of PE/H2O2/Fe2+ energy and b) with different energy sources (UV radiation at λ = 254 and 365 nm) in PE/UVPE/H2O2/UV and PE/H2O2/Fe2+/UV systems; ultrasonic radiation (50/60 kHZ) PE/H2O2/US. The degradation and oxidation/mineralization processes of PE were studied according to different physico-chemical parameters, such as: reaction time, pH value, concentration of the oxidant (H2O2), of the catalyst (Fe2+ ions), the intensity of UV rays , substrate concentration, lack and presence of surfactants. In the Fenton oxidation of PE from single and mixed aqueous solutions, both the degradation performance and the degree of oxidation/mineralization were found to depend on the molar ratio of reactants [H2O2]0/[Fe2+]0 and substrate. In the presence of UV rays, the speed of the oxidation reaction increases and this leads to the reduction of the oxidation time by 4-5 times. It was established that the initial concentration of the substrate in simple model systems influences the oxidation rate, and the dependence of the oxidation rate on the PE concentration in the coordinateslnW = f (lnC) represents a straight line, which tells us that the oxidation reaction is of order 1. In presence of the anionic surfactant SBS containing benzene rings, the CCOt values of the mixed drug system [AMX : CLX : DFC: SBS]0 were reduced by three units during 30 min, and the oxidation/mineralization achieved, on average, 84 %, compared to the mixed system [AMX : CLX : DFC]0. The presence of the cationic surfactant in the mixed systems [AMX : CLX : DFC: SBS : CTAB]0 from whose structure the benzene ring is missing, increases the CCOt values. These increases are caused by the lack of benzene rings in the CTAB surfactant structure, which are quite stable and undergo both oxidation and mineralization more slowly, even in the presence of OH radicals.
Empoderamiento participativo para la Gobernanza de mujeres rurales en el Perú
Authors: Cueva Rodríguez Medali , Castillo Santamaria Bessy , Palacios Sánchez José M. , Ferrer Chata Elizabeth Norma , Terry Ponte Otto Franklin , Ramírez Calderón Luis Enrique , Cueva Rodríguez Oscar B.
Published: April 2024

La investigación enfoca la participación de la mujer del mundo rural, donde su vida diaria se genera en el entorno de su familia y su comunidad, gesta que logra mediante su capacidad y poder de decisión para lograr el empoderamiento en la sociedad. Partiendo de la premisa de construir el desarrollo local con esfuerzo, siendo éstos basados en la actividad agrícola y ganadera, tiene que enfrentar necesidades ante el desafío por el elevado costo de vida, sin que éstas cuenten con estudios culminados y en su gran mayoría son analfabetos que no asistieron a un centro educativo en ningún momento de su vida. Para lo cual, se aborda como objetivo conocer la participación de las mujeres rurales en la gobernanza de la gesta de su comunidad en Perú. Trabajo desarrollado mediante el enfoque cualitativo, de tipo básica, no experimental, mediante el paradigma interpretativo, haciendo uso del método fenomenológico y hermenéutico, para trabajar mediante la técnica de entrevista y como instrumento la guía de entrevista estructurada, orientando a las participantes mujeres rurales de las zonas de influencia de un distrito de la región Cajamarca, donde se gestionó nueve (9) preguntas a cuatro (4) participantes mujeres representantes y líderes de su comunidad como son: (una representante del Fondo de Cooperación para el Desarrollo Social – FONCODES perteneciente al Estado peruano; una representante de la “Cooperativa Porcón” dedicada a trabajar en equidad de género y religiosidad, una investigadora del Instituto Nacional de Innovación Agraria-INIA, perteneciente al sector agropecuario, y finalmente una ciudadana líder de la comunidad, que trabaja en bien de la sociedad) entrevista que duró entre 40 a 60 minutos. Existe deficiencia en la participación de mujeres en las zonas rurales en cuanto a la gobernanza, poco interés en la gestión de la comunidad, participación activa de programas asistenciales emitidos por el gobierno central, así como, labores diarias de campo en la siembra, cosecha, venta de sus productos a pequeña escala, sumado a ello, la ganadería con la producción de derivados lácteos como: queso, mantequilla, manjar, mermeladas, yogur, entre otros, basados en la conservación de su cultura y ancestros que permanecen en el legado dejado por sus antepasados, influenciando en su vida comunal y de sus hijos, en tal sentido de lograr el empoderamiento en la empleabilidad laboral al culminar sus estudios. Por lo que se concluye, las mujeres rurales consideran que trabajar de forma conjunta con sus familias logran avanzar y evitar actos negativos en la sociedad, sin importar la gestión como posibles candidatas o autoridades en su ámbito.
İngiltere'de Kalkınma Ajansları
Authors: Koca Mehmet
Published: April 2024

Günümüz dünyasında bölgeler arası dengesizlik, gelişmiş ve gelişmekte olan tüm ülkelerin karşı karşıya oldukları önemli bir problem haline gelmiştir. Bu problem daha çok az gelişmiş ülkelerde kendini daha belirgin bir şekilde göstermekle birlikte sosyoekonomik gelişmişlik düzeyi bakımından gelişmiş ülkelerin içinde de kendi aralarında göreli olarak gelişme farklılıkları bulunan bölgeler ortaya çıkmıştır. Ülke içinde zamanla ortaya çıkan bu gelişmişlik farkları pek çok sosyal ve ekonomik sorunları beraberinde getirmiş ve bu nedenle ülke düzeyinde sosyoekonomik entegrasyonu sağlamak amacıyla, bölgeler arasındaki farklılıkları azaltmaya yönelik uygulamalar hayata geçirilmeye başlanmıştır. Bu minvalde özellikle küreselleşme sürecinde daha da ön plana çıkan değişim ve dönüşümler kalkınma politikalarının amaç ve uygulamalarında da değişimlere sebebiyet vermiş ve bu durum beraberinde yeni bir yönetim ve örgütlenme yapısının zorunluluğunu ortaya çıkarmıştır. Yaşanan bu paradigma değişimi zaman içerisinde merkeziyetçi bir yaklaşımdan ziyade âdem-i merkezi bir yapıya doğru dönüşmeye başlamış ve bu süreç dahilinde kalkınma ajansları ortaya çıkmıştır. İngiltere’de de bölgesel gelişmişlik farklarının giderilmesi adına kalkınma ajansları kurulmuştur. Bununla birlikte 2000’li yılların başı itibariyle başlayan etkinlik tartışmaları çerçevesinde yaşanan tartışmalar ve 2010 yılında iktidara gelen koalisyon hükümetinin bölge ölçeğini terk etmesi sonucunda 2011 yılı itibariyle İngiltere’de kalkınma ajanslarının faaliyetlerine son verildiği görülmüştür. Bu çalışmanın konusunu İngiltere’deki kalkınma ajansları oluşturmaktadır. Çalışma ile İngiltere’deki kalkınma ajanslarının tarihsel gelişimi ve mevcut durumunun ortaya konulması amaçlanmıştır. Çalışmada literatür taramasına dayalı nitel bir araştırma yöntemi takip edilmiştir.
Factors Affecting In Quality Of Healthcare Services In Critical Care Departments Of General Hospitals
Authors: Alwaleed Alsuwailem ; Kholoud Alsomali
Published: April 2024

Background: Healthcare organizations strive for quality in their service delivery as a way of keeping up with the competing trends in clients’ attraction. In the process, they have become cognizant of the key performance indicators to help track progress and performance. Despite the growing interests in healthcare KPIs, little has been done in terms of KPIs in the general hospitals, especially in the critical care units. Therefore, this study was designed to assess the implications of KPIs on the quality of healthcare service delivery in the critical care department in a general hospital in the Kingdom of Saudi Arabia.

Methods: Quantitative descriptive quantitative research was conducted a among 300 healthcare workers in the critical care unit of a general hospital in Saudi Arabia. Data was collected after receiving ethical approval and participants’ consent. Accordingly, the researcher administered the questionnaires to the selected participants using a pre-made research questionnaire using the 5-point Likert scale. The collected data was analyzed using linear regression and the descriptive statistical tests of SPSS, version 26.

Results: From the descriptive statistical analysis, two key performance indictors outstood in the critical care department of general hospitals. These include experiences with hospital staff (mean=3.143; SD =2.00) and Patient Readmission Rate (mean=3.106; SD=1.419). A statistically significant relationship was also noted between patient readmission rate (p=.030), experiences with hospital staff (p=.070) and staff's commitment to patients (p=.016) and the quality of critical care care services.

Conclusion: Key performance indicators are crucial in tracking the milestones made in healthcare organizations towards meeting patients’ needs. Healthcare system management need to develop a means of tracking their key performance indicators for informed improvements in quality of their services.
Asma bronquial en niños y factores de mal pronóstico.
Authors: Flores España Ximena del Cisne
Published: April 2024

El asma bronquial es una enfermedad crónica del sistema respiratorio caracterizada por la inflamación de las vías respiratorias, lo que provoca episodios recurrentes disnea, sibilancias, opresión en el pecho y tos. Estos síntomas suelen ser desencadenados por diversos facto-res, como alérgenos, irritantes, ejercicio físico, cambios en el clima o infecciones respiratorias. Es importante tener en cuenta que el pronóstico del asma puede mejorar con un manejo adecuado, que incluye el seguimiento regular con un médico especializado, adherencia al trata-miento prescrito, identificación y evitación de desencadenantes, y educación sobre la enferme-dad y su manejo. A pesar de los diversos esfuerzos dirigidos hacia el control del asma en la población infantil, un número significativo continúan experimentando afectaciones en la función pulmonar, incluso cuando siguen un tratamiento que se supone efectivo. El objetivo del presente estudio es determinar los factores de mal pronóstico que exacerban el cuadro clínico del paciente asmático, la metodología a utilizar fue la revisión bibliográfica mediante la búsqueda de literatura a través de las bases de datos de Scielo, CUIDEN, PubMed, Dialnet, Cochrane, etc. Dentro de los resultados obtenidos: la rinorrea sin catarro, sexo masculino, episodios de, padres asmáticos, dermatitis atópica y hospitalización por enfermedades respiratorias en los últimos seis meses constituyen factores de mal pronóstico asociados a crisis graves y mal control en asma bronquial. Conclusión: abordar los factores de mal pronóstico en el asma bronquial, ofrece un mejor control de la enfermedad, reduce la carga de la enfermedad para los pacientes y mejorar su calidad de vida.
Social media uses amongst adolescents: motives, minority stress and eudaimonic well-being
Authors: López-Sáez Miguel Ángel , Pérez-Torres Vanesa , Pastor Yolanda , Lobato-Rincón Luis-Lucio , Thomas-Currás Helena , Angulo-Brunet Ariadna
Published: April 2024

Introducción: la evidencia científica sobre los efectos del uso de medios sociales en línea sobre el bienestar en la población adolescente es heterogénea. En general, usos pasivos (recepción, visualización de contenidos sin interacción) y mayor tiempo de pantalla se relacionan con menor bienestar en contraposición con usos activos (interacciones directas e intercambios interpersonales). Objetivo: Esta investigación explora el tipo y motivo de uso de medios sociales, estableciendo su diferencia por identidad de género y orientación sexual, así como efectos sobre bienestar eudaimónico y estrés de minorías. Método: estudio transversal, 1259 adolescentes; 14-19 años (M = 16.19; DE = 1.08). Escala motivos de uso de redes sociales, Bienestar eudaimónico, Estrés de minorías, tiempo de pantalla, tipo de perfil. Resultados: mayor tiempo de uso se relaciona con búsqueda de pareja, conexión social o establecer amistades. Los adolescentes gay y bisexuales (GB) perciben más estresores distales en línea. Las mujeres tienen mayores niveles de bienestar. Discusión: los perfiles públicos en hombres GB favorecen la autoexpresión, aunque el estrés de minorías puede relacionarse con discriminación, rechazo o exclusión. La socialización diferenciada puede contribuir a un nivel elevado de bienestar en las mujeres. Usos activos como pasivos favorecen el bienestar eudaimónico de los adolescentes.

Introduction: The scientific evidence regarding the effects of online social media use on the well-being of adolescents is mixed. In general, passive uses (receiving, viewing content without interacting) and more screen time are related to lower well-being when compared with active uses (direct interactions and interpersonal exchanges). Objectives: This study examines the types and motives for social media usage amongst adolescents, differentiating them by gender identity and sexual orientation, as well as its effects on eudaimonic well-being and minority stress. Method: A cross-sectional study was conducted with 1259 adolescents, aged 14 to 19 (M = 16.19; SD = 1.08), analysing the Scale of Motives for Using Social Networking Sites, eudaimonic well-being, the Sexual Minority Adolescent Stress Inventory, screen time and profile type. Results: The results found that longer use time is related to finding partners, social connection and friendships; that gay and bisexual (GB) adolescents perceive more distal stressors online; and that females have higher levels of well-being. Discussion: The public profiles of GB males increase self-expression, although minority stress can be related to discrimination, rejection or exclusion. Differentiated socialization may contribute to a higher level of well-being in females, with both active and passive uses positively effecting eudaimonic well-being in adolescents.
Subjective memory complaints in young people; their relationship with objective cognitive performance and the role of neuroticism
Authors: Crespo-Sanmiguel Isabel , Zapater-Fajarí Mariola , Garrido-Chaves Ruth , Hidalgo Vanesa , Salvador Alicia
Published: April 2024

Perceptions of recurrent forgetfulness or episodes of distraction in daily life are referred to as subjective memory complaints (SMCs). Their nature has been extensively studied in older adults, but their significance and relationship with neurocognitive performance have not been fully addressed in younger adults. Some psychological traits have been suggested as possible moderators of the association between objective and subjective memory performance. The first aim of this study was to analyze the correspondence between the objective and subjective perception of memory failures in young people. Second, we studied whether the psychological trait of neuroticism could be influencing this relationship. To do this, we measured SMCs, different cognitive domains (episodic and working memory and executive functions), and neuroticism in 80 young men and women. Results showed that only immediate episodic memory was statistically related to SMCs. Interestingly, the negative relationships between objective and subjective memory performance only appeared in participants with higher neuroticism. Thus, memory complaints reported by young people could reflect poorer immediate episodic memory performance, whereas neuroticism would play a main role in the association between memory deficits and SMCs. This study provides data that can help to better understand SMCs in young people.

Las percepciones de olvidos recurrentes o episodios de distracción en la vida diaria se denominan quejas subjetivas de memoria (QSM). Su naturaleza se ha estudiado ampliamente en adultos mayores, pero su importancia y relación con el rendimiento neurocognitivo no se han abordado por completo en adultos más jóvenes. Se han sugerido algunos rasgos psicológicos como posibles moderadores de la asociación entre el rendimiento de la memoria objetiva y subjetiva. El primer objetivo de este estudio fue analizar la correspondencia entre la percepción objetiva y subjetiva de los fallos de memoria en jóvenes. En segundo lugar, estudiamos si el rasgo psicológico del neuroticismo podría estar influyendo en esta relación. Para ello, medimos QSM, diferentes dominios cognitivos (memoria episódica y de trabajo y funciones ejecutivas) y neuroticismo en 80 hombres y mujeres jóvenes. Los resultados mostraron que solo la memoria episódica inmediata estaba estadísticamente relacionada con los QSM. Curiosamente, las relaciones negativas entre el rendimiento de la memoria objetiva y subjetiva solo aparecieron en participantes con mayor neuroticismo. Por lo tanto, las quejas de memoria reportadas por los jóvenes podrían reflejar un peor rendimiento de la memoria episódica inmediata, mientras que el neuroticismo jugaría un papel principal en la asociación entre los déficits de memoria y las QSM. Este estudio proporciona datos que pueden ayudar a comprender mejor las QSM en los jóvenes.
Acceptance and Commitment Therapy on suicidal behavior: a systematic review
Authors: Ortas-Barajas Francisco , Manchón Javier
Published: April 2024

Suicide has emerged as a pressing global issue affecting both society and public health. In this context, Acceptance and Commitment Therapy (ACT) could prove effective in its approach, supported by evidence of the relationship between certain components of ACT and suicidal behavior. Thus, the present study aims to conduct a systematic review on the efficacy of ACT in suicidal behavior. For this, the PRISMA protocol was followed, using the following databases: PsycInfo, PubMed, Scopus and PsicoDoc. Initially, 108 potentially relevant publications were obtained, 13 of which were finally included in the review. We analyzed study quality using a risk of bias assessment instrument. As a result, statistically significant decreases in suicidal ideation (SI) and suicide risk factors were observed. In addition, some studies indicated statistically significant relationships between increased psychological flexibility and decreased SI. While the data suggested the potential effectiveness of ACT in reducing suicidal ideation (SI), more experimental studies are needed to consider the complexity of suicidal behavior and explore the processes of change involved.

El suicidio se ha convertido en un problema social y de salud pública a nivel mundial. En este sentido, la Terapia de Aceptación y Compromiso (ACT) podría ser eficaz en su abordaje, existiendo evidencia sobre la relación entre algunos de sus componentes y la conducta suicida. Así, el presente estudio tuvo por objetivo realizar una revisión sistemática sobre la eficacia de ACT en conducta suicida. Para ello se siguió el protocolo PRISMA, empleando las siguientes bases de datos: PsycInfo, PubMed, Scopus y PsicoDoc. Inicialmente se obtuvieron 108 publicaciones potencialmente relevantes, de las cuales, finalmente, 13 fueron incluidas en la revisión. La calidad de los estudios se analizó a través de un instrumento de evaluación de riesgo de sesgos. Como resultados, a nivel general se observaron disminuciones estadísticamente significativas en ideación suicida (IS) y factores de riesgo de suicidio. Además, algunos estudios señalaron relaciones estadísticamente significativas entre un aumento de flexibilidad psicológica y la disminución de IS. Si bien los datos apuntaron a una posible eficacia de ACT en la reducción de IS, es necesario llevar a cabo mayor número de estudios experimentales que contemplen la complejidad de la conducta suicida y exploren los procesos de cambio implicados.
Near Hexagons of Order \((3,t)\) having a Big Quad
Authors:   Department of Mathematics: Algebra and Geometry, Ghent. University, Krijgslaan 281 (S25), B-9000 Gent, Belgium, Bruyn Bart De , Gao Mou ,   Department of Mathematics: Algebra and Geometry, Ghent. University, Krijgslaan 281 (S25), B-9000 Gent, Belgium
Published: April 2024

We classify all near hexagons of order (3,t) that contain a big quad. We show that, up to isomorphism, there are ten such near hexagons.
On Ve-Degree and Ev-Degree Based Topological Invariants of Chemical Structures
Authors:   Department of Mathematics, Minhaj University, Lahore, Pakistan, Nigar Niat , Alam Sajid Mahboob ,   Department of Mathematics, Minhaj University, Lahore, Pakistan, Rasheed Muhammad Waheed ,   Department of Mathematics, Division of Science and Technology, University of Education, Lahore, Pakistan, Farahani Mohammad Reza ,   Department of Mathematics and Computer Science, Iran University of Science and Technology(IUST), Narmak, Tehran, 16844, Iran, Alaeiyan Mehdi ,   Department of Mathematics and Computer Science, Iran University of Science and Technology(IUST), Narmak, Tehran, 16844, Iran, Cancan Murat ,   Faculty of Education, Van Yuzuncu Yl University, Zeve Campus, Tuba, 65080, Van, Turkey
Published: April 2024

In the realm of graph theory, recent developments have introduced novel concepts, notably the ν ε -degree and ε ν -degree, offering expedited computations compared to traditional degree-based topological indices (TIs). These TIs serve as indispensable molecular descriptors for assessing chemical compound characteristics. This manuscript aims to meticulously compute a spectrum of TIs for silicon carbide S i C 4 - I [ r , s ] , with a specific focus on the ε ν -degree Zagreb index, the ν ε -degree Geometric-Arithmetic index, the ε ν -degree Randić index, the ν ε -degree Atom-bond connectivity index, the ν ε -degree Harmonic index, and the ν ε -degree Sum connectivity index. This study contributes to the ongoing advancement of graph theory applications in chemical compound analysis, elucidating the nuanced structural properties inherent in silicon carbide molecules.
On Decompositions of \(\mathbf{K_{18k}}\) and \(\mathbf{K_{18k+1}}\) into Certain Connected Bicyclic Graphs with Nine Edges
Authors:   Department of Mathematics, Illinois State University, USA, Froncek Dalibor ,   Department of Mathematics and Statistics, University of Minnesota Duluth, USA, Sailstad Andrew ,   School of Mathematics, University of Minnesota, Twin Cities, USA
Published: April 2024

We show that connected, bicyclic graphs on nine edges with at least one cycle other than C 3 decompose the complete graphs K 18 k and K 18 k + 1 , for k ≥ 1 , when the necessary conditions allow for such a decomposition. This complements previous results by Freyberg, Froncek, Jeffries, Jensen, and Sailstad on connected bicyclic triangular graphs.
The Index Weighted Hermitian Adjacency Matrices for Mixed Graphs
Authors:   School of Mathematics and Statistics, Central China Normal University, Wuhan, P.R. China, Wang Zheng , She Tao ,   School of Mathematics and Statistics, Central China Normal University, Wuhan, P.R. China, Wang Chunxiang ,   School of Mathematics and Statistics, Central China Normal University, Wuhan, P.R. China
Published: April 2024

Based on the Hermitian adjacency matrices of second kind introduced by Mohar [1] and weighted adjacency matrices introduced in [2], we define a kind of index weighted Hermitian adjacency matrices of mixed graphs. In this paper we characterize the structure of mixed graphs which are cospectral to their underlying graphs, then we determine a upper bound on the spectral radius of mixed graphs with maximum degree Δ , and characterize the corresponding extremal graphs.
The current achievements of immune checkpoint inhibitor therapy in the treatment of cancer and the newly discovered immune checkpoints in recent years
Authors: Wu Han
Published: April 2024

Immune checkpoint inhibitor therapy (ICIs) is a new type of cancer treatment method developed in the past 20 years and is a very eye-catching innovation in the development of clinical immunotherapy. With the emphasis on cancer treatment and our deepening understanding of the human immune system and malignant tumors, the mechanisms of various immune cell responses involved in cancer recognition and elimination have been gradually discovered and clarified one by one [2]. This therapy aims to enhance and activate the anti-tumor immune activity of cytotoxic T cells by blocking negative regulatory molecules on anti-tumor T cells or ligands on antigen-presenting cells and tumor cells through immune inhibitors. This therapy is of considerable importance in the current treatment and research of immuno-oncology. From the beginning, it was only used to treat a specific tumor to gradually treat a variety of different and common tumors. At the same time, it has also been used since the beginning. What started as a single specific inhibitor or two gradually developed into various dosage forms that can be combined. It has become one of the most clinically important methods for treating cancer.
Application and difficulties of deep learning in drug target discovery
Authors: Kuang Xiaoqian
Published: April 2024

The integration of deep learning technology within the domain of drug target discovery represents a cutting-edge approach in the pharmaceutical sciences. This paper delves into the methods and prevailing issues associated with the application of deep learning in the identification of new drug targets. We initiate with an exposition of the fundamental concepts and methodologies underpinning deep learning, subsequently illuminating its utilization in the realm of drug target discovery. Specific attention is given to the deployment of architectures like convolutional neural networks (CNNs) and recurrent neural networks (RNNs) among others.
By interpreting experimental outcomes, it has been discerned that deep learning potentially enhances the precision of identifying drug targets. Nonetheless, this technological arena is not devoid of challenges. A significant hurdle lies in the interpretability of the models—understanding why and how these models arrive at their conclusions is often non-trivial. Moreover, the efficacy of deep learning is heavily reliant on the quality and volume of the datasets employed; insufficient or poor-quality data can severely impede the performance and reliability of predictive models.Through this inquiry, we aim to furnish novel insights into the utilization of deep learning for drug target discovery and underscore the challenges that must be addressed. The perspectives offered herein are vital to propel the progress of this burgeoning field, paving the way for more effective and efficient drug discovery processes.
Application of Critical Chain Project Management on Engine Maintenance at PT. Rekatama Putra Gegana Aviation
Authors: Raga Ridha Azka , Pertiwi Husna Putri , Jasrial Jasrial
Published: April 2024

Planning is a crucial element for aircraft maintenance companies to achieve higher profitability. However, in practice, the company still employs traditional planning methods, which are deemed inefficient as they do not consider the productivity of each task involved, leading to issues arising from human behavior tendencies causing additional time for task completion. Aircraft maintenance planning can be improved by employing the Critical Chain Project Management (CCPM) method, which offers a different approach to determining the time and cost of aircraft maintenance. This method addresses multitasking, student syndrome, Parkinson's law, and provides buffers at the end of tasks. Analysis results show that the completion time for tasks within the company, totaling 76 days, differs by 14 days compared to the completion time using the CCPM method, which is 62 days. This indicates that employing the CCPM method for engine maintenance is more effective and efficient. The efficiency achieved amounts to Rp7,036,323.