bluuebunny/crossref_metadata_2025 huggingface dataset:
BH4 activates CaMKK2 and rescues the cardiomyopathic phenotype in rodent models of diabetes
Authors: Kim Hyoung Kyu , Ko Tae Hee , Song In-Sung , Jeong Yu Jeong , Heo Hye Jin , Jeong Seung Hun , Kim Min , Park Nam Mi , Seo Dae Yun , Kha Pham Trong , Kim Sun-Woo , Lee Sung Ryul , Cho Sung Woo , Won Jong Chul , Youm Jae Boum , Ko Kyung Soo , Rhee Byoung Doo , Kim Nari , Cho Kyoung Im , Shimizu Ippei , Minamino Tohru , Ha Nam-Chul , Park Young Shik , Nilius Bernd , Han Jin
Published: July 2020

Diabetic cardiomyopathy (DCM) is a major cause of mortality/morbidity in diabetes mellitus patients. Although tetrahydrobiopterin (BH4) shows therapeutic potential as an endogenous cardiovascular target, its effect on myocardial cells and mitochondria in DCM and the underlying mechanisms remain unknown. Here, we determined the involvement of BH4 deficiency in DCM and the therapeutic potential of BH4 supplementation in a rodent DCM model. We observed a decreased BH4:total biopterin ratio in heart and mitochondria accompanied by cardiac remodeling, lower cardiac contractility, and mitochondrial dysfunction. Prolonged BH4 supplementation improved cardiac function, corrected morphological abnormalities in cardiac muscle, and increased mitochondrial activity. Proteomics analysis revealed oxidative phosphorylation (OXPHOS) as the BH4-targeted biological pathway in diabetic hearts as well as BH4-mediated rescue of down-regulated peroxisome proliferator-activated receptor-γ coactivator 1-α (PGC-1α) signaling as a key modulator of OXPHOS and mitochondrial biogenesis. Mechanistically, BH4 bound to calcium/calmodulin-dependent protein kinase kinase 2 (CaMKK2) and activated downstream AMP-activated protein kinase/cAMP response element binding protein/PGC-1α signaling to rescue mitochondrial and cardiac dysfunction in DCM. These results suggest BH4 as a novel endogenous activator of CaMKK2.
PARTICULARITIES OF DRIVER’S WORK AND REST SCHEDULE CONDITIONS IN ORGANIZED CHILDREN CARRIAGE IN INTERCITY CONNECTION
Authors: Ianuchkova O. E. , Ianuchkov M. R. , Iakunina N. V.
Published: July 2020

Introduction. The article is devoted to the description of the shedule development particularities and a drivers’ work and rest schedule adjustment in an organized children carriage considering their age in an intercity connection. During the interurban transportation after first four hours and thirty minutes of uninterrupted driving, a special break for the rest is provided for drivers on the way lasting at least 45 minutes. This period can be divided into two or more parts, but the first part should last at least 15 minutes and the last one at least thirty minutes. At the same time children of different age groups perceive long distant travels variously due to their physiological development. The restriction of physical activity during a long time may have a negative impact on children’s physical and mental state. Children may have some problems with behavior control during long distant travels, it may lead to a travel rules violation, they remove their seat belts, start to walk around the bus, etc. The dependencies of the covered distance and time on a children’s age were identified based on the study results of the intercity children carriage process. The findings may be applied in a bus route timetables development, a drivers’ work and rest schedule adjustment during an organized children carriage in an intercity connection and also when planning transport infrastructure objects along popular tourist routes or frequently used transportation directions for students.

The purpose of article is the description of a traffic schedule particularities development and a drivers’ work and rest schedule adjustment in an organized children carriage considering their age in an intercity connection. The scientific novelty lies in methodology used for a drivers’ work and rest schedule adjustment which depends on a distance and travel time in an organized children carriage by buses in an intercity connection and on the age of the carried children.

Materials and techniques. While writing the article the methods of a passengers carriage theory, a statistical and systematic analysis, a transport process theory and also some other scientific methods and techniques were used.

Results. The results have advisory nature and are proposed for use in a drivers’ work and rest schedule adjustment in an organized children carriage considering their age in an intercity connection.

Discussion and conclusion. For the carriage of different aged children the scheme of traffic according to a children age group should be chosen. 4 age groups of children each of which correspond to a certain traffic and rest time on the way were identified during the study.
LOW TEMPERATURES EFFECT ON THERMAL CONDITIONS OF DZ-98 AUTOGRADER HYDRAULIC UNITS
Authors: Okhlopkov T. N.
Published: July 2020

Introduction.The article discusses the climatic conditions of Yakutia, as well as the cooling process of the hydraulic system of DZ-98 motor grader in order to prevent violation of the thermal regime of hydraulic units under the influence of low temperatures, taking into account the wind blowing and operating conditions. The surface temperature of the hydraulic units was measured on January 16, 2018 in the city of Yakutsk on the basis of Yakutdorstroi joint-stock company at an ambient temperature of -42 ° С.

Materials and methods.To ensure a reliable operation of the hydraulic system at low temperatures, hydraulic units must provide a supply of working fluid under pressure, regardless of changes in ambient temperature. The thermal regime of hydraulic units is characterized by three main parameters: pressure, temperature and volume. In the North, where the ambient winter temperature varies from -27 ° С to -49 ° С, the absolute temperature is the determining parameter. Studying the problem, theories of heat conduction and heat transfer in solids, hydrodynamics, and differential equations were used.

Results.Natural and climatic data, as well as the recorded surface temperature of hydraulic units, allow to determine the number of days with a critically negative temperature, the heat transfer of hydraulic units and the regularity of its change depending on the operating mode.
EXPERIMENTAL INVESTIGATION ON NATURAL FIBER ALONG WITH SILICA FUME IN CONVENTIONAL CONCRETE
Authors: G Venkatesan , P. Kapgate Bharat , K Rajkumar
Published: July 2020

Concrete is globally recognized for its long term service period in the application of concrete. In the region of five billion tons of concrete are utilized more or less in the planet and increasing every year. In view of the environmental problems faced today considering the fast reduction of natural resources like sand and aggregate. Owing to the growth of Science and Technology in recent decades, there is a modification in the practice of concrete along with some additives as the complement for strength and workability.Basalt Fiber is categorized under the Mineral additive and brought into usage in early 1920’s in the period of World war for Military purposes. Silica fume is hugely known for its durability and it increases the density of concrete. On Another hand, the building are often subjected to risk of corrosion and Sustainability, the application of any element in the proportions of concrete will possess the property of Resisting and rejuvenating the nature of Concrete.
Information security controls for multi-cloud and microservices
Authors: Alok Kumar
Published: July 2020

The current study, provides the information security control process involved in multi-cloud and micro services. In recent years, there has been great demand to provide two layer securities in almost all sectors with the use of information technologies. Hence the present study highlights on the information securities and their importance.
Fundamentals of deep data science
Authors: Naveena M
Published: July 2020

The present study reports the fundamentals of deep data sciences and their emerging roles across the globe. The influence of deep data science plays important roles in information science. The tools and softwares designed using big data science are creating huge impact on the society. Keeping these into consideration, the study reports the beneficial aspect of it along with basic information.
The influence of multi cloud strategy
Authors: Sasikanth Reddy Mandat
Published: July 2020

The study describes the architecture of multi cloud strategy in the IT and computer sector.The study provides the techniques which are involved in the cloud strategy, its usages and importance in the growing world. The study also highlights the working and elements involved in multi cloud strategy along with the future applications of it.
新时代民营经济高质量发展的难点与策略
Authors: 柯 美胜
Published: July 2020

在国家的大力投入下，中国的民营企业迎来了巨大的发展机遇，经过多年的发展，在项目投资、财税政策、金融政策、资金投入和基础建设等问题上有了非常大的改善，但是在新时代下依然存在总体规模、整体实力、产业结构、产业科技含量等问题。论文讨论了新时代民营经济高质量发展的难点与策略，以顺应新时代的发展。
浅析基层行政事业单位内部控制规范实施中存在的问题及对策
Authors: 邓 水英
Published: July 2020

2015 年 12 月 21 日，财政部印发《关于全面推进行政事业单位内部控制建设的指导意见》（财会 [2015]24 号）要求：各级行政事业单位要在 2020 年全面建成并有效实施内部控制。经调查研究发现，中国基层行政事业单位内部控制目前已初步建成，但因内部控制意识淡薄、制度落实不到位、内部控制制度编制水平参差不齐、专业胜任能力不足、评价与监督流于形式、成果运用较差等一系列问题导致内控规范实施受挫。基于此，论文针对基层行政事业单位内控规范实施过程中存在的问题进行分析和探讨。
企业排污权交易行为及交易制度稳定性影响
Authors: 安 鸿飞
Published: July 2020

在过去，中国在环境污染物防治方面采取的方式较为单一，主要以政府主导和治理为主，致使企业被动按照指令执行污染物防治。企业排污权的设置坚持以良好的生态环境为导向，排污权交易制度的设置始终以排污企业为主体，既要满足污染物的排放又可以做到合理管控，不造成环境的二次污染。论文通过了解企业排污权交易的概况、发展历程以及应用，分析企业排污权交易制度的构成因素和完善内容。
大数据技术对审计的影响研究
Authors: 汪 泳
Published: July 2020

伴随着移动互联网、云计算等应用的到来，大数据技术也迎来蓬勃发展。把大数据运用于组织实践管理并从中挖掘有价值的信息渐成趋势。大数据战略的实施为企业带来丰富的数据资源，帮助其准确洞察市场、抓住商机提高企业竞争力的同时，也给企业数据存储与数据分析带来了极大挑战。大数据时代的到来，为审计的转型升级提供了技术支持、指明了方向，并引起了学术界的广泛关注。论文重点介绍当前的时代背景下，大数据对审计产生的影响及审计人员的应对策略。
中国民营企业上市公司的跨国并购研究——以美的集团并购德国 KUKA 为例
Authors: 陈 云 , 苗 聪
Published: July 2020

目前，中国的经济发展处于转型的阶段，中国的民营企业也跟随海外并购相关政策的出台来到了海外并购的舞台中。中国民营企业如今的选择较之前会更加的宽泛和多元化，这也促使中国民营企业在海外并购项目数量上独占鳌头。对民营企业海外并购案例的研究不仅有利于民营企业更好的借鉴海外并购相关经验，而且对海外并购行为的发展提供了一个良好契机，如能促进企业进行规模扩张、销售渠道渐趋多样化、有效提高技术水平等。与此同时，这些良好的契机对于民营企业的整体发展来说也起到了借鉴作用，能够增强其他民营企业的海外并购风险意识。
Kajian stilistika dalam antologi puisi negeri dongeng karya mahasiswa universitas peradaban
Authors: Farkhatin Lilis , Purnama Wulan , Irma Cintya Nurika
Published: July 2020

Stylistics is basically the activity of writers using language, especially language that triggers creativity to sort out the use of language. In this research using the study of stylistics in the poetry anthology of "Negeri Dongeng" by the students of Peradaban University. This research is a qualitative descriptive study. The data in this study are descriptive words in the Poetry Anthology of "Negeri Dongeng" by Indonesian Language and Literature Education Students at the Peradaban UniversityÂ  and reference books related to research. Data collection techniques with document analysis that starts from the stages of reading, recording, and analyzing data in the Anthology Poem "Negeri Dongeng". The data validity technique in this research is data triangulation. The purpose of this research is to explain the study of stylistics in the anthology of "Negeri Dongeng" poetry by Peradaban UniversityÂ  Students. The results of this study are to explain 6 problems regarding the use of sound style, word style, sentence style, discourse style, the existence of figurative language in the use of figurative language types: metaphor, personification, paradox, hyperbole. While the use of images, namely: vision, hearing, smell, motion, touch. Which is dominated by figurative language imagery.
Sosok Ibu dalam Puisi Bunda Airmata Karya M.H. Ainun Najib dan Puisi Ibu Karya Widji Tukul: Suatu Kajian Sastra Bandingan
Authors: Fisari Nika , Wulandari Yosi
Published: July 2020

This study aims to determine the relationship of the poetry of the mother of tears by M.H Ainun Najib with the poem of the mother of Widji Tukul. Analysis in this theory uses a comparative literary theory that discusses metaphors, symbols and relevance in both poems. The method of this study uses an intertextuality approach. This research found the mother's figure as a parent and in God's eyes so that there is a relationship that connects a mother's tears in God's eyes with a mother's tears for affection for her children, namely the relation of Islamic elements in the contents of the two poems.
Captive Insurance Companies: Do They Provide "Insurance"?
Authors: McCulloch Stewart
Published: July 2020

This article explores captive insurance companies and focuses on whether a true "insurance" relationship exists between captive insurer and its insured. After providing a general background to captives, the article briefly visits the legal definition of "insurance" and then considers the captive insurer/insured relationship to determine whether an "insurance" relationship exists. Finally, the article considers situations where the existence or absence of a true "insurance" relationship may be of significance.
Consumer Contract Governance in a Deregulating Japan
Authors: Taylor Veronica
Published: July 2020

This article analyses patterns of governance - how public and private policy networks are managed - in consumer contracts in a deregulating Japan. It outlines the structure of Japan's service industry and consumer problems, before considering the framework for a juridical intervention, bureaucratic regulation and pressures for further legislative activity. As the question of how to curb excesses of power in a deregulated environment governed by multiple agents become more acute, consumer governance seems likely to change, and with it the utility of current theories of how law operates in Japan.
Rationality or Intuition? - The Assessment of the Quantum of Damages for Personal injuries in Solomon Islands
Authors: Corrin Care Jennifer
Published: July 2020

The development of a Pacific islands jurisprudence is considered in this article in the specific context of six recent judgments of Solomon Islands' courts, which dealt with the rules relating to the assessment of damages for personal injury. The discussion of the issues and the rules enunciated by courts is of social and economic interest, not only as a matter of Solomon Islands' law but also for its value for other small Pacific states where similar issues are having to be resolved.
Electoral Reform in Japan: A Comparative Constitutional Law Perspective
Authors: Asaka Kichimoto
Published: July 2020

The electoral systems of both Japan and New Zealand were recently reformed, and both states had their first elections under the new regimes in October 1996. This article considers some features of the two electoral systems from the point of view of the legal context in which the electoral reforms were made, and of the main reasons for those reforms.
Maximizing the impact of E-Therapy and Serious Gaming: Time for a paradigm shift
Authors: Fleming Theresa , de Beurs D , Khazaal Y , Gaggioli A , Riva G , Botella C , Baños RM , Aschieri F , Bavin LM , Kleiboer A , Merry S , Lau HM , Riper H
Published: July 2020

© 2016 Fleming, de Beurs, Khazaal, Gaggioli, Riva, Botella, Baños, Aschieri, Bavin, Kleiboer, Merry, Lau and Riper. Internet interventions for mental health, including serious games, online programs, and apps, hold promise for increasing access to evidence-based treatments and prevention. Many such interventions have been shown to be effective and acceptable in trials; however, uptake and adherence outside of trials is seldom reported, and where it is, adherence at least, generally appears to be underwhelming. In response, an international Collaboration On Maximizing the impact of E-Therapy and Serious Gaming (COMETS) was formed. In this perspectives' paper, we call for a paradigm shift to increase the impact of internet interventions toward the ultimate goal of improved population mental health. We propose four pillars for change: (1) increased focus on user-centered approaches, including both user-centered design of programs and greater individualization within programs, with the latter perhaps utilizing increased modularization; (2) Increased emphasis on engagement utilizing processes such as gaming, gamification, telepresence, and persuasive technology; (3) Increased collaboration in program development, testing, and data sharing, across both sectors and regions, in order to achieve higher quality, more sustainable outcomes with greater reach; and (4) Rapid testing and implementation, including the measurement of reach, engagement, and effectiveness, and timely implementation. We suggest it is time for researchers, clinicians, developers, and end-users to collaborate on these aspects in order to maximize the impact of e-therapies and serious gaming.
Trial for the Prevention of Depression (TriPoD) in final-year secondary students: Study protocol for a cluster randomised controlled trial
Authors: Perry Y , Calear AL , Mackinnon A , Batterham PJ , Licinio J , King C , Thomsen N , Scott J , Donker T , Merry S , Fleming Theresa , Stasiak K , Werner-Seidler A , Christensen H
Published: July 2020

© 2015 Perry et al. Background: Evidence suggests that current treatments cannot fully alleviate the burden of disease associated with depression but that prevention approaches offer a promising opportunity to further reduce this burden. Adolescence is a critical period in the development of mental illness, and final school examinations are a significant and nearly universal stressor that may act as a trigger for mental health difficulties such as depression. The aim of the present trial is to investigate the impact of SPARX-R, an online, gamified intervention based on cognitive behavioural principles, on the prevention of depression in secondary school students before their final examinations. Methods/Design: Government, independent and Catholic secondary schools in New South Wales, Australia, will be recruited to participate in the trial. All students enrolled in their final year of high school (year 12) in participating schools will be invited to participate. To account for possible attrition, the target sample size was set at 1600 participants across 30 schools. Participating schools will be cluster randomised at the school level to receive either SPARX-R or lifeSTYLE, an attention-controlled placebo comparator. The control intervention is an online program aimed at maintaining a healthy lifestyle. The primary outcome will be symptoms of depression, and secondary outcomes will include symptoms of anxiety, suicidal ideation and behaviours, stigma and academic performance. Additional measures of cost-effectiveness, as well as process variables (e.g., adherence, acceptability) and potential predictors of response to treatment, will be collected. Consenting parents will be invited to complete measures regarding their own mental health and expectations for their child. Assessments will be conducted pre- and post-intervention and at 6- and 18-month follow-up. Primary analyses will compare changes in levels of depressive symptomatology for the intervention group relative to the attention control condition using mixed-effects model repeated-measures analyses to account for clustering within schools. Discussion: This is the first trial of a universal depression prevention intervention delivered to school students in advance of a specific, significant stressor. If found to be effective, this program may offer schools a new approach to preparing students for their final year of schooling. Trial registration: Australian New Zealand Clinical Trials Registry identifier: ACTRN12614000316606. Registered 25 March 2014.
Views of young people in rural Australia on SPARX, a fantasy world developed for New Zealand youth with depression
Authors: Cheek C , Bridgman H , Fleming Theresa , Cummings E , Ellis L , Lucassen MFG , Shepherd M , Skinner T
Published: July 2020

Background: A randomized control trial demonstrated that a computerized cognitive behavioral therapy (cCBT) program (Smart, Positive, Active, Realistic, X-factor thoughts [SPARX]) was an appealing and efficacious treatment for depression for adolescents in New Zealand. Little is known about the acceptability of computerized therapy programs for rural Australians and the suitability of computerized programs developed in one cultural context when used in another country. Issues such as accents and local differences in health care access might mean adjustments to programs are required. Objective: This study sought to explore the acceptability of SPARX by youth in rural Australia and to explore whether and how young people would wish to access such a program. Methods: Focus groups and semistructured interviews were conducted with 16 young people attending two youth-focused community services in a small, rural Tasmanian town. An inductive data-driven approach was used to identify themes using the interview transcripts as the primary data source. Interpretation was supported by demographic data, observer notes, and content analysis. Results: Participants reported that young people want help for mental health issues but they have an even stronger need for controlling how they access services. In particular, they considered protecting their privacy in their small community to be paramount. Participants thought computerized therapy was a promising way to increase access to treatment for youth in rural and remote areas if offered with or without therapist support and via settings other than school. The design features of SPARX that were perceived to be useful, included the narrative structure of the program, the use of different characters, the personalization of an avatar, "socialization" with the Guide character, optional journaling, and the use of encouraging feedback. Participants did not consider (New Zealand) accents off-putting. Young people believed the SPARX program would appeal to those who play computer games generally, but may be less appealing for those who do not. Conclusions: The findings suggest that computerized therapy offered in ways that support privacy and choice can improve access to treatment for rural youth. Foreign accents and style may not be off-putting to teenage users when the program uses a playful fantasy genre, as it is consistent with their expectation of fantasy worlds, and it is in a medium with which they already have a level of competence. Rather, issues of engaging design and confidential access appeared to be more important. These findings suggest a proven tool once formally assessed at a local level can be adopted cross-nationally.
Vaccines, polarising divides and the role of public health
Authors: Dew Kevin , Donovan S
Published: July 2020

No description supplied
Ascertaining patients’ understandings of their condition: a conversation analysis of contradictory norms in cancer specialist consultations
Authors: Dew Kevin , Barton J , Stairmand J , Sarfati D , Signal L
Published: July 2020

© 2019, © 2019 Informa UK Limited, trading as Taylor & Francis Group. Patient-centred care requires patients to be active participants in decision-making in consultations. Decision-making participation requires patients to understand their condition and to be able to convey their health literacy to medical specialists they encounter. Based on conversation analysis of 18 audio-recorded consultations between cancer patients and a range of cancer care specialists, this article analyses the ways cancer specialists attempt to ascertain their patient’s understanding of their disease. Cancer specialists routinely enquire about their patient’s understanding. In doing so, they phrase enquiries in different ways, resulting in different patient responses. How questions are phrased can require patients to deal with contradictory norms in the consultation, such as the patient being competent but not assuming medical expertise, and potentially hinder patient participation. Alternatively, questions can allow patients to draw on their own experience and so facilitate greater patient involvement. Questions aimed directly at the patient’s medical understanding result in minimal or negative responses. In contrast, questions directed at what the patient has been told or has experienced, elicit longer and more in-depth responses from the patient. This analysis illuminates the co-construction of cancer specialist consultations and suggests simple ways in which patient involvement in the consultation can be facilitated.
ntergenerational earnings mobility in Taiwan: 1990–2010.
Authors: Chu Yu-Wei , Lin Ming-Jen
Published: July 2020

© 2019, Springer-Verlag GmbH Germany, part of Springer Nature. In this paper, we study the intergenerational earnings mobility between fathers and sons in Taiwan. We apply the two-sample approach developed by Björklund and Jäntti (Am Econ Rev 87(5):1009–1018, 1997) and find that the intergenerational earnings elasticity in Taiwan was around 0.4–0.5 in both the early 1990s and the late 2000s. We also estimate the intergenerational rank association in earnings to have been around 0.3 in both periods. Intergenerational earnings mobility in Taiwan is similar to that in less mobile countries such as the USA, and it appears to remain stable during a period of rapid economic development.
Cancer care decision-making and treatment consent: An observational study of patients’ and clinicians’ rights
Authors: Dew Kevin , Signal L , Stairmand J , Simpson A , Sarfati D
Published: July 2020

© The Author(s) 2018. This study identified ways in which patients and medical specialists negotiated decisions about cancer treatment by observing decision-making discussion in situ. Audio-recordings of cancer care consultations with 18 patients, their support people, and their medical specialists, including medical oncologists, radiation oncologists and surgeons were collected in different regions of New Zealand. Patients were followed up with interviews and specialists provided consultation debriefings. The interpretation of the data drew on the concepts of epistemic and deontic rights to argue that in complex consultations, such as occur in cancer care, we need to reconsider the simple dichotomy of preferred consultations styles as paternalistic or based on shared decision-making. Decision-making is a dynamic process with specialists and patients linked into networks that impact on decision-making and where rights to knowledge and rights to decision-making are interactionally negotiated. The level of information and understanding that patients desire to exercise rights needs to be reconsidered.
Can local NURBS refinement be achieved by modifying only the user interface?
Authors: Dodgson Neil , Kosinka J
Published: July 2020

© 2015 The Authors. NURBS patches have a serious restriction: they are constrained to a strict rectangular topology. This means that a request to insert a single new control point will cause a row of control points to appear across the NURBS patch, a global refinement of control. We investigate a method that can hide unwanted control points from the user so that the user's interaction is with local, rather than global, refinement. Our method requires only straightforward modification of the user interface and the data structures that represent the control mesh, making it simpler than alternatives that use hierarchical or T-constructions. Our results show that our method is effective in many cases but has limitations where inserting a single new control point in certain cases will still cause a cascade of new control points to appear across the NURBS patch.
Cancer Care Decision Making in Multidisciplinary Meetings
Authors: Dew Kevin , Stubbe M , Signal L , Stairmand J , Dennett E , Koea J , Simpson A , Sarfati D , Cunningham C , Batten L , Ellison-Loschmann L , Barton J , Holdaway M
Published: July 2020

© The Author(s) 2014. Little research has been undertaken on the actual decision-making processes in cancer care multidisciplinary meetings (MDMs). This article was based on a qualitative observational study of two regional cancer treatment centers in New Zealand. We audiorecorded 10 meetings in which 106 patient cases were discussed. Members of the meetings categorized cases in varying ways, drew on a range of sources of authority, expressed different value positions, and utilized a variety of strategies to justify their actions. An important dimension of authority was encountered authority - the authority a clinician has because of meeting the patient. The MDM chairperson can play an important role in making explicit the sources of authority being drawn on and the value positions of members to provide more clarity to the decision-making process. Attending to issues of process, authority, and values in MDMs has the potential to improve cancer care decision making and ultimately, health outcomes.
Limits to Neoliberal Reforms in the Health Sector: The Case of Pharmaceutical Management in New Zealand
Authors: Dew Kevin , Davis A
Published: July 2020

In New Zealand in 1993, a pharmaceutical management agency (PHARMAC) was established during the height of neoliberal reforms in the health sector. The agency's relationship with pharmaceutical companies, patient lobby groups, and health professionals has been hostile at times, but despite this hostility, PHARMAC has remained substantially independent from political interference. This article draws on critical theory and Durkheimian perspectives to explain how such a strong regulatory organization was established during a time when attempts were made to reshape the health sector to conform to a neoliberal agenda. An analysis of historical and contemporary issues demonstrates the contradictory position of the state in relation to the regulation and subsidization of pharmaceuticals, with conflicting demands to retain popular support, restrain state expenditure, and respond to expectations to provide pharmaceuticals to its citizens. This article demonstrates how the establishment of PHARMAC reconciles these contradictory demands, arguing that it removes decision making from political control and has been able to sustain its place by appealing to objective assessment criteria. This case signals limits of the neoliberal agenda. © 2014, Baywood Publishing Co., Inc.
Book Review: Moneish Bhatia, Scott Poynting and Waqas Tufail (eds) Media, Crime and Racism
Authors: Salman Sarah
Published: July 2020

No description supplied
Cultural Criminology and Gender Consciousness: Moving Feminist Theory From Margin to Center
Authors: Naegler L , Salman Sarah
Published: July 2020

© 2016, © The Author(s) 2016. Cultural criminology emerged in the mid-nineties with defining texts written by Jock Young, Keith Hayward, and Jeff Ferrell, among others. Since its inception, it has been criticized for its shallow connections with feminist theory. While in theory cultural criminology clearly acknowledges the influence of feminist scholarship, it has in practice often only superficially ‘added’ on gender and sexuality to its scholarly investigations. Yet, as we argue, research identified with cultural criminology has much to gain from feminist theory. This article reviews a range of cultural criminological scholarship, particularly studies of subcultures, edgework, and terrorism. We investigate three themes significant for feminist research: masculinities and femininities, sexual attraction and sexualities, and intersectionality. Such themes, if better incorporated, would strengthen cultural criminology by increasing the explanatory power of resulting analyses. We conclude by advocating that feminist ideas be routinely integrated into cultural criminological research.
Providing gender-affirming hormone therapy through primary care: Service users' and health professionals' experiences of a pilot clinic
Authors: Ker A , Fraser Gloria , Lyons Antonia , Stephenson C , Fleming T
Published: July 2020

© 2020 CSIRO Publishing Journal Compilation © Royal New Zealand College of General Practitioners 2020 This is an open access article licensed under a. INTRODUCTION: Primary health care providers are playing an increasingly important role in providing gender-affirming health care for gender diverse people. This article explores the experiences of a primary care-based pilot clinic providing gender-affirming hormone therapy in Wellington, New Zealand. AIM: To evaluate service users' and health professionals' experiences of a pilot clinic at Mauri Ora (Victoria University of Wellington's Student Health and Counselling Service) that provided gender-affirming hormones through primary care. METHODS: In-depth interviews were conducted with four (out of six) service users and four health professionals about their perspectives on the clinic. Interviews were transcribed verbatim and analysed using thematic analysis. RESULTS: Three themes were identified in service users' interviews, who discussed receiving affirming care due to the clinic's accessibility, relationship-centred care and timeliness. Three themes were identified in the health professionals' interviews, who described how the clinic involves partnership, affirms users' gender and agency, and is adaptable to other primary care settings. Both service users and health professionals discussed concerns about the lack of adequate funding for primary care services and the tensions between addressing mental health needs and accessing timely care. DISCUSSION: The experiences of service users and health professionals confirm the value of providing gender-affirming hormone therapy in primary care. Models based in primary care are likely to increase accessibility, depathologise gender diversity and reduce wait times.
التحرُّش بالمرأة العاملة في المراكز التجاريَّة بالمجتمع السعودي: دراسة وصفية
Authors: Almazyad Haya  A.
Published: July 2020

المستخلص

سعت الدراسة الحالية إلى اكتشاف أنواع التحرُّش التي تتعرَّض لها المرأة العاملة في المراكز التجارية، وأساليب تعامل المرأة مع مواقف التحرُّش في المجتمع السعودي. وتعدُّ هذه الدراسة من الدراسات الوصفية التي استخدمت منهج المسح الاجتماعي، حيث صمَّمت الباحثة استبانة لقياس أنواع التحرُّش. وشاركت في الدراسة 268 امرأة عاملة في المراكز التجارية في مدينة الرياض. وأوضحت نتائج الدراسة موافقة المفردات على تعرُّضهن للتحرُّش البصري بنسبة بلغت 51.8%، واللفظي بنسبة 44.5%، وبلغت نسبة التحرَّش باللمس 37.6%, وبلغت نسبة التحرش غير المباشر، كالمتابعة والملاحقة 43.59%، وأخيرًا بلغت نسبة التحرُّش الإلكتروني 36.26%. كما أظهرت نتائج الدراسة أن نسبة موافقة أفراد العينة على أن المبالغة في مظهر المرأة يجعلها ضحية للتحرش بلغت 67.9% وبناء عليه، وأوصت الدراسة بضرورة وضع سياسات وإجراءات خاصة بالمراكز التجارية، تحت إشراف وزارة الموارد البشرية والتنمية الاجتماعية، للتعامل مع بلاغات التحرُّش.
التربية المرورية في المنهج الإسلامي وآثار تطبيقها في الحد من حوادث السير
Authors: Arabi Amenchar Omar bin Al
Published: July 2020

تتناول الدراسة موضوع التربية المرورية في المنهج الإسلامي، من حيث المفهوم، والأسس، والأهداف، وآثار تطبيقها في الحد من حوادث السير، وقد انبثقت من الحاجة الملحة إلى منهج تربوي مروري من منظور إسلامي للتقليل من حوادث السير، وتمت الدراسة بناء على الآيات القرآنية والأحاديث النبوية الصحيحة الواردة في تنظيم التعامل المروري وأخلاقيات الطريق، وقد استخدم الباحث المنهج الوصفي التحليلي.

ومن نتائج الدراسة أن التربية المرورية في المنهج الإسلامي بعناصرها المختلفة (المفـاهيم، والأسس، والأهداف) تغرس في الإنسان المسلم قيم المحافظة على الحياة الإنسانية، والمال، والبيئة، والأنظمة والقوانين؛ ما يؤثر إيجابيًّا في السلوك المروري، ويؤدي إلى الحد من حوادث السير.

وتوصلت الدراسة إلى عدة توصيات، أهمها: تربية الأبناء على التعامل السليم مع الطريق ومستخدميه، وتقرير مادة تعليمية مستقلة للتربية المرورية في كل مراحل التعليم، ودمج التربية المرورية في مختلف المقررات الدراسية، وفتح أقسام متخصصة في الكليات التربوية تُعنى بالمرور، وتوظيف الإعلام للعناية بالوعي المروري.
A CRITICAL REVIEW: TAMAKA SHWASA (BRONCHIAL ASTHMA)
Authors: Narhari Saka Vaishnavi
Published: July 2020

Out of most morbid disorders, the disease shwas is also becoming a major health problem of the society. Difficulties in breathing, cough are common health complains which everyone experiences throughout their life with different magnitude. Such complains are found in every age group. Dyspnea due to respiratory diseases comes under ShwasaRoga. Maha- Urdhva-Chinna-Tamaka and Kshudra are the types of ShwasaRoga. Bronchial asthma is a chronic inflammatory disease of airways characterized by cough, difficulty in breathing and wheeze. Exposure to dust, smoke, recurrent respiratory infections and climatic changes are chief triggering factors of this disease. Bronchial asthma and its associated features clinically correspond to the Tamaka Shwasa described in Ayurveda.
POLICE INTEGRITY IN THE COURTROOM WHEN TESTIFYING
Authors: Neely Jr. Phillip R. , Cillo JD Joseph
Published: July 2020

The integrity of police when testifying in the courtroom is critical for the trust, confidence, and reputation of both the police force and the criminal justice system. Despite this, however, perjury is a major problem affecting the criminal justice system as can be evident from its high preference across jurisdictions in the entire nation. In addition, it is a real concern to the ability of the criminal justice system to deliver justice to all in the society. However, perjury is a complex problem to deal with due to the ethical nature of different influencers. The influencers range from strict requirements on the rights of defendants for the police to comply with to the inherent demand on officers to ensure successful convictions and implied support by court officials, prosecution, and police departments within the criminal justice system. Accordingly, the collaboration of the different stakeholders in this problem of justice remains a promising solution.
La tecnología en el uso sostenible del agua para riego en México. El caso del acuífero de Tecamachalco, Puebla, 2017
Authors: Carrillo-Huerta Mario Miguel , Gómez Bretón Enrique
Published: July 2020

En 2012, 170 de los 653 acuíferos de México estaban en condiciones deficitarias y cinco, incluido el de Tecamachalco, habían sido declarados en peligro de extinción, afectando la sostenibilidad del desarrollo de la región. Este trabajo reporta los resultados de un estudio de campo realizado en 2016-2017 entre 121 productores agrícolas de esa zona con el objeto de evaluar cómo el mercado, las políticas del gobierno y la acción de los usuarios contribuían o no a la sostenibilidad del acuífero. Se muestra aquí que los usuarios y el gobierno influyen más porque los primeros usan tecnología adecuada en el riego, y ésta es parte de la asistencia técnica que incluye la política pública de administración del agua en México.
Peran dan Tugas Dukun Bayi dalam Penanganan Kesehatan di Desa Talang Perapat, Kecamatan Seluma Barat, Kabupaten Seluma
Authors: Heriadi Meddyan
Published: July 2020

Abstrak: Peran dan Tugas  Dukun Bayi dalam Penanganan Kesehatan di Desa Talang Perapat,  Kecamatan Seluma Barat, Kabupaten Seluma. Kematian ibu dan bayi, aborsi, dan prosesi pengobatan yang tidak sejalan dengan nilai agama menjadi momok negatif yang disematkan pada dukun bayi selama ini. Namun, meskipun demikian masyarakat masih tetap mempercayakan pengobatan pada dukun tersebut, dengan alasan biaya yang terjangkau, obat-obatan alami, serta ketidakmampuan bidan dalam mengobati penyakit tertentu, khususnya yang berhubungan dengan penyakit supranatural. Tujuan dari penelitian ini adalah untuk mengkaji tugas dukun bayi khususnya di Desa Talang Perapat, Kecamatan Seluma Barat, Kabupaten Seluma. Permasalahan yang akan dibahas nantinya yakni, bagaimana tugas dukun bayi dalam memberikan pengobatan terhadap warga setempat. Dalam kajian ini peneliti menggunakan metode kualitatif dengan instrumen wawancara terhadap dukun bayi setempat, yaitu Ibu Patelawati. Tugas dukun bayi di Desa Talang Perapat Kecamatan Seluma Barat mencakup beberapa hal: Pertama tugas yang berkenaan dengan wanita dan anak. Pada bagian ini tugas dukun merujuk pada tugas sebelum persalinan yang meliputi mendeteksi kehamilan; memijat rahim yang mengalami goncangan; dan  memimpin syukuran kehamilan 8 bulan. Tugas berikutnya yaitu membantu proses persalinan. Selanjutnya, tugas dukun bayi pun berlajut ke fase pasca-persalinan. Yang mana  meliputi: perawatan terhadap ibu pasa-melahirkan; membasuh ari-ari bayi; memimpin upacara maling aiak; mengobati penyakit nonmedis yang berhubungan dengan supranatural; mengobati penyakit medis  seperti turunnya rahim pada ibu yang telah melahirkan dan demam pada bayi dan anak.  Selain itu, pengobatan pada wanita remaja juga dilakukan seperti pengobatan pada nyeri buang air kecil dan nyeri saat menstruasi. Kemudian, pengobatan juga dilakukan pada pria, seperti susah mendapat keturunan, Peghut Telulugh, dan demam.
The Implementation of Quality Control Management for Student Guidance in Man 1 Parepare
Authors: Halik Abdul , Das St. Wardah Hanafie
Published: July 2020

The purpose of this study is to control the quality control of the guidance of the students, to minimize the quality control management barrier in the field of student guidance, and to formulate the applicative concept of the implementation of the quality control management field guidance of students in State Islamic Senior High School (MAN) 1 Parepare. This research method is case study at MAN 1 Parepare as the research object, data collecting technique are observation, interview, document study, triangulation, and Focus Group Discussion (FGD). Data analysis techniques are the identification and reduction of data, analysis, verification and conclusion. As results, MAN 1 Parepare has not applied quality management guidance and counselling learners. Barriers to the implementation of quality control management are limited human resources, insufficient infrastructure, limited budgets, uncompetitive learners, low external support, and limited partnerships. The implementation of quality control management of guidance and counselling field of students in MAN 1 Parepare is to carry out management functions in quality control, beginning with availability of quality standard system, quality procedure, quality audit, and quality control. The institutional requirements of the application of quality control management are the political will of the head of madrasah, the commitment and togetherness of human resources, the fulfilled infrastructure, the adequate budget, and the broad partnership.
The Utilization of Picture and Picture Strategy: An Effective Way to Improve Efl Students’ Writing Ability in Madrasah Tsanawiyah
Authors: Hakim M. Arif Rahman , Susanti Tri Nur , Asiyah Asiyah , Abidin Mohamad Jafre Zainol
Published: July 2020

The aim of this study is to find out whether or not there was a significant difference between students who were taught using picture and picture strategy and that of those who were not in writing recount text. The study employed a quasi-experimental study. The population in this study were the second grade students of Madrasah Tsanawiyah in Bengkulu city, Indonesia with a total number are 89 students. Out of this population, 60 students were taken as the sample. They are divided into two groups; experiement and control group, which consisted of 30 students for each group. The data were collected by using writing test. The data obtained were analyzed by using t- test formula. The data were found that the result of t-count post-test (6.34) was higher than t- table (2.00) with α = 5 % and df= 58. The finding of this research shows that there is a significant difference between students in Madrasah Tsanawiyah who are taught using picture and picture strategy and that of those who are not. Based on the result on the study, picture and picture strategy can improve students’ writing achievement in writing recount text evidently
Age, Religion, and Taboos Influence Subsistence Hunting by Indigenous People of the Lower Madeira River, Brazilian Amazon
Authors: Knoop Simon B. , Morcatty Thais Q. , El Bizri Hani R. , Cheyne Susan M.
Published: July 2020

Subsistence hunting is an essential livelihood strategy of Indigenous people in the Amazon. The present study examines the aspects influencing hunting practices by the Indigenous Maraguá people in the central Amazon, Brazil. We used a Generalized Additive Model to test the effects of economic (breeding of domestic animals), demographic (individual age), cultural (preference for hunting vs. fishing), and religious (Adventism, an Evangelical denomination vs. other Christian beliefs) factors on the frequency of hunting. We used a Principal Coordinate Analysis to assess how religious taboos associated with Adventism determine the composition of target taxa. The average hunting frequency of the 26 interviewees was 10.2 trips per month. Sixty-five percent (n = 17) of the interviewees were non-Adventists, and 35% (n = 9) were Adventists. Both younger and older people hunted less frequently than those in the middle age group (c. 50 years old). We found no influence of religious affiliation or breeding of domestic animals on the frequency of hunting. Ten taxa were cited as favorite game by the informants, and while Adventists avoided eating several mammalian taxa, non-Adventists did not declare any religious dietary restrictions. This study is one of the first to approach the influence of modern Christian belief systems on hunting habits of Indigenous Amazonian people. We highlight the importance of considering of cultural and religious particularities in research on subsistence hunting and design of management plans for Indigenous lands in Amazonia.
An Analysis of the Listening Comprehension in CET-6——Illustrated by the CET-6 Test on June, 2018
Authors: Liu Hongying
Published: July 2020

The College English Test Band Six (CET-6) is one of the most widely applied exam across China. As a national teaching test, CET-6 is sponsored by the Department of higher education of the Ministry of education of The People’s Republic of China and held twice a year. In this study, 77 sophomores of different majors were tested using the listening test in June 2018. It is ensured that the test method is exactly same as that of CET-6. The purpose of this paper is to analyze the content and specification of CET-6 listening comprehension test, and to evaluate this part in detail according to the real data, including score report and item analysis, trying to provide some enlightenment for the revision of the examination.
Features of the course and treatment of glaucoma during pregnancy
Authors: Chernyakova T. V. , Brezhnev A. Yu. , Gazizova I. R. , Kuroyedov A. V. , Seleznev A. V.
Published: July 2020

In the review we have integrated all up-to-date knowledge concerning clinical course and treatment of glaucoma among pregnant women to help specialists choose a proper policy of treatment for such a complicated group of patients. Glaucoma is a chronic progressive disease. It rarely occurs among childbearing aged women. Nevertheless the probability to manage pregnant patients having glaucoma has been recently increasing. The situation is complicated by the fact that there are no recommendations on how to treat glaucoma among pregnant women. As we know, eye pressure is progressively going down from the first to the third trimester, so we often have to correct hypotensive therapy. Besides, it is necessary to take into account the effect of applied medicines on mother health and evaluate possible teratogenic complications for a fetus. The only medicine against glaucoma which belongs to category B according to FDA classification is brimonidine. Medicines of the other groups should be prescribed with care. Laser treatment or surgery may also be a relevant decision when monitoring patients who are planning pregnancy or just bearing a child. Such treatment should be also accompanied by medicines.
Diagnosis and treatment lung damage in systemic scleroderma
Authors: Bilichenko T. N.
Published: July 2020

The progressing system sclerosis (PSS), M34.0 according to IСД-10 — an autoimmune disease with characteristic spastic vascular reactions as Reynaud’s syndrome and obliterating endarteritis with ischemic violations at which the specific frustration which are followed by activation of a fibrosis and excess adjournment of collagen in fabrics develop. The progressing current of PSS leads to development of irreversible fibrous changes of skin, the musculoskeletal device, internals (lungs, heart, a digestive tract, kidneys), to malfunction of bodies, an disability of patients with the general bad forecast of a disease. Thanks to modern therapy severe damage of kidneys, meets at PSS more rare and changes in lungs in a clinical picture come to the forefront. Early diagnostics of PSS and the differentiated approach to treatment of a disease can change the course and prognosis of the disease considerably.