bluuebunny/crossref_metadata_2025 huggingface dataset:
Optimal Control of an Active Suspension System Applying Distributed Parameter Simulation Test
Authors: Maradey Lázaro Jessica Gissella , Esteban  Villegas Helio Sneyder , Aldana Afanador Andres Felipe , Cáceres Mojica Kevin Sebastian
Published: July 2023

Automotive is one of the most important industries in the world, which lead to a need for continuous improvement of vehicles and their internal systems. Suspension systems have been improved for better vehicle performance and passenger comfort, keeping the tire in contact with the road surface. Active suspensions require optimal control to modulate the flow of energy and generate the control force by implementing active actuators able to provide negative damping and a wider range of forces and velocities. This article aims the design of an active suspension system based on LQG and LQR controller evaluating its performance in a distributed parameters simulation using COMSOL Multiphysics® and MATLAB®. The quarter car model is proposed and is linearized to design the optimal control (LQG and LQR) respectively. An early mathematical simulation is developed in MATLAB (R) software to verify and compare the open and closed loop results. Finally, the full system model is implemented in COMSOL Multiphysics (R) software considering rigid materials and the controller to analyze the distributed parameters simulation results.
Bayes' Theorem for Multi-Bearing Faults Diagnosis
Authors: Ts. YEO SIANG CHUAN  , Ir. Dr. Lim Meng Hee  , Dr. Hui Kar Hoou  , Eng Hoe Cheng
Published: July 2023

During the process of fault diagnosis for automated machinery, support vector machines is one of the suitable choices to categorize multiple faults for machinery. Regardless of the volume of sampling data, support vector machines can handle a high number of input features. It was learned that support vector machines could only sense binary fault classification (such as faulty or healthy). However, the classification accuracy was found to be lower when using support vector machines to diagnose multi-bearing faults classifications. This is because the multiple classification problem will be reduced into several sub-problems of binary classification when support vector machines adapt to multi-bearing faults classifications. From there, many contradictory results will occur from every support vector machine model. In order to solve the situation, the combination of Support Vector Machines and Bayes’ Theorem is introduced to every single support vector machine model to overcome the conflicting results. This method will also increase classification accuracy. The proposed Support Vector Machines - Bayes’ Theorem method has resulted in an increase in the accuracy of the fault diagnosis model. The analysis result has shown an accuracy from 72% to 95%. It proved that Support Vector Machines - Bayes’ Theorem continuously eliminates and refines conflicting results from the original support vector machine model. Compared to the existing support vector machine, the proposed Support Vector Machines - Bayes’ Theorem has proven its effectiveness in diagnosing the multi-bearing faults problem classification.
Convection heat transfer of stepped basin single slope solar still: A numerical investigation
Authors: M. Varun  , S. Subhani  , R. Senthil Kumar
Published: July 2023

Solar-powered desalination is a quick and easy way to make drinking water. Numerous solar distillation systems have been investigated for various parameter modifications based on local resource availability. In this work, a solar still with a modified stepped basin is investigated to raise the rate of internal evaporation and, therefore the output yield of the solar still. Stepped basin solar stills are taken into consideration for the study since they are very effective because the water's surface exposure to radiation is greater. Thus, increasing the rate of internal water evaporation enhances the rate of convective heat transfer between the evaporating and condensing surfaces, leading to improved and consistent output. The two-dimensional stepped basin single slope solar still was investigated and contrasted with the traditional single slope still in terms of heat transfer and fluid dynamics. To optimize the configuration for better performance in various types of climatic and operational circumstances that imitate the scenario of daily life, design elements such as the number of steps and the different heights of the basin are also taken into account. Each step was added with far more success than the one before it, up until the length was reduced to 1.16% of the entire shorter length. This numerical study enables us to draw the conclusion that the rise in natural heat transfer rate with the addition of steps is mostly caused by the increased surface area and the inherently restrictive nature within the domain. Additionally, with an increase in Rayleigh number, Ra, the gradient variations of the traditional single slope solar still overheat transfer features have been greatly regulated and successfully raised for the modified stepped basin Solar still.
Statistical analysis, modeling and multi-objective optimization of parameters intermittent turning process of AISI D3
Authors: Fethi Khelfaoui  , M. A. Yallese  , N. Ouelaa  , S. Chihaoui  , S. Belhadi
Published: July 2023

Intermittent machining is characterized by its complex and irregular context. This intermittency causes machining to occur under difficult conditions that greatly influence the technological performance parameters. The aim of the present work is to evaluate the effects of input parameters, cutting speed, Vc, depth of cut, ap, tool nose radius, r and feed rate, f, on surface roughness, Ra, tangential cutting force, Fz, motor power consumption, Pm, cutting power, Pc and material removal rate (MRR), during intermittent turning (IT) of AISI D3 tool steel. Machining was performed with a triple CVD coated carbide tool (AI2O3/TiC/TiCN) by adopting a Taguchi L9 (3^4) experimental design. The ANOVA and RSM methods were used to analyze the effects of cutting factors on the outputs parameters resulting in statistical prediction models. In addition, a multi-objective optimization of the cutting conditions exploiting the desirability function (DF) was done according to four cases of relative importance corresponding to different industrial contexts. Furthermore, the grey relational analysis (GRA) method was applied and compared with the DF method. The results show that the optimal regime found by the DF method, (r =1.6mm, Vc= 240 m/min, f = 0.084 mm/rev and ap = 0.64 mm), favors Ra and MRR. On the other hand, for the GRA method, the combination of (r = 0.4 mm, Vc = 240 m/min f = 0.08 mm/rev and ap = 0.3 mm) favors the minimization of Fz, Pm and Pc. This work presents an originality because the results found are very useful in the field of optimization for a better control of the process IT.
Information packaging strategies serving the communicative needs of speakers
Authors:   Ss Cyril and Methodius University, Skopje, North Macedonia, Stojanovska-Ilievska Natasha
Published: July 2023

This paper presents the findings of a study of diverse information packaging strategies employed by speakers of English to better serve their communicative needs in given contexts, based on examples from the British National Corpus (BNC). More precisely, the analysis centres around the information packaging possibilities offered by light verb constructions (LVCs) in comparison to their full verb counterparts. As is conventionally recognised in previous studies, LVCs formally stretch the predicate over a verbal and a nominal element (e.g. to order vs to give an order). It is precisely this fact that makes it possible for speakers to structure their utterances in various ways. Thus, either all participants are overtly realized in the sentence and the communicative focus could be placed on each one of them depending on the context, or some participants are reduced, which is the preferred strategy when their identity is implied, unfamiliar, irrelevant or would rather be concealed.
The lexico-phraseological profile of professional film reviews published by the British media: A corpus-linguistic study
Authors:   University of Bielsko-Biala, Poland, Szczygłowska Tatiana
Published: July 2023

Using corpus linguistic techniques, this exploratory study is intended to provide a descriptive in-sight into frequent lexical bundles, keywords and key terms as well as selected lexical markers of style used in a corpus of professional film reviews. The research material includes 210 domain-specific texts from the years 2020-2021, extracted from the websites of six British newspapers, magazines and institutions offering guides for moviegoers. The results show that the analyzed reviews make frequent use of general cinematic terms and more specific lexis denoting the different types and (sub)genres of cinematic productions repre-sented by the reviewed films. Other salient lexical features include a high concentration of referential but low concentration of stance bundles, though attitudinal items, particularly evaluation adjectives, signifi-cantly enrich the lexical inventory of the reviews. The presented data may have important pedagogic appli-cations in the area of teaching authentic English to future film reviewers and film journalists.
Cognitive “warning signs” in human trafficking media texts
Authors:   Borys Grinchenko Kyiv Metropolitan University, Ukraine, Paliichuk Elina
Published: July 2023

This paper focuses on image schema manifestations in media texts on human trafficking, which may perform the role of “warning” signals in anti-trafficking media campaigns. For this, a conceptual analysis was done to establish profiled image schemas, and a survey was conducted to measure the readerʼs response to two types of texts on human trafficking (HT), different in genre and schemata organ-isation. The texts were selected as experimental material representing typical human trafficking media discourse. The participants were divided into control (G1) and experimental (G2) groups according to the type of text they were exposed to. G1 read an expository text (T1) and G2 read a media narrative (T2). The respondents of G2 showed a significant tendency for a higher degree of involvement in the problem of human trafficking when reading T2 as contrasted to the responses of G1 to T1. G2 identified their reaction as a feeling being in danger. Looking back to T2, it was clear that respondents reacted to verbal manifesta-tions of prevailing CONTAINMENT and SCALE/ PROCESS/UP schemata clusters. G1 gave the weaker emo-tional response toT1 with verbal manifestations of UP, BLOCKAGE, and COUNTERFORCE schemata. It can be assumed that CONTAINMENT is the image schema organising spatial representation of human traffick-ing from the victimʼs perspective, conveying the feeling of being contained, being in a difficult situation, being in an enclosed space, supported with other schemata manifestations through the lens of the concept of big-ness, large scale, growing process, etc. The results may be used in anti-trafficking content as a new method-ology for raising awareness in a target audience vulnerable to HT.
Between V and T address: The translation of English address terms into Polish in serial storytelling (the case of Doc)
Authors:   University of Białystok, Poland, Rozumko Agata
Published: July 2023

This study is concerned with the translation of address terms in serial storytelling. It adopts the interpersonal pragmatics perspective on address terms and treats them as elements of fictional charactersʼ relational work, i.e. the work they do to negotiate their relationships in interaction. More specifically, this paper focuses on the renditions of the form Doc as used by detective Jane Rizzoli to address doctor Maura Isles in the Polish translation of Tess Gerritsenʼs Rizzoli and Isles crime fiction series. Since English and Polish have different address systems (N-V-T and T-V, respectively) and there are no informal terms equivalent to Doc to address a female doctor in Polish, its renditions depend entirely on the translatorʼs ability to understand and recreate the charactersʼ relational interaction. The Polish translators of the Rizzoli and Isles series showed different degrees of attention to the interactional coherence of the translation, which is why some of its parts contain inappropriate and impolite address forms. Overall, the relational work done by the characters has largely been domesticated in the translation and adapted to Polish speech patterns and rules of politeness. Consequently, shifts in the charactersʼ address mode take place at different moments in the translation than they do in the original version, and the form Doc is rendered in a variety of ways (both formal and informal) depending on the stage of the charactersʼ relational interaction.
Federal Educational Program of Preschool Education: Aspects of Management Problems and Solutions
Authors:   Nizhny Novgorod Institute of the Education Development, Belousova Rimma Yu. , Novoselova Antonina N. ,   Antonina N. Novoselova Nizhny Novgorod State Research University named after N. I. Lobachevsky, Podoplelova Natalia M. ,   Nizhny Novgorod Institute of the Education Development
Published: July 2023

The article presents the main results of a study of scientific, methodological and substantive support for additional professional education of the leaders and teachers of the preschool educational organization on the implementation of federal educational program in the context of the requirements of actual legislation, which are pedagogical innovation for the practice of managing preschool education of the Russian Federation. The authors indicate the problems identified during the analysis of requests and professional difficulties of the leading and pedagogical workers of the preschool educational organization conducted by the Department of Preschool Education in the process of implementing the programs of additional professional education of the heads of preschool educational organization in the context of the Federal Law “On Education in the Russian Federation”, taking into account the Federal Law 304-FL and changes in the federal educational standard of preschool education. As a tool, diagnostic maps presented in the methodological recommendations of the Ministry of Education of the Russian Federation were used. The results of the activities of the department of preschool education on the organizational and methodological support of the practice of developing educational programs of preschool educational organizations are also reflected. As a methodological support of work with children-foreigners, an additional general development program “Russian Language as a Native” was proposed at the innovative sites of the Nizhny Novgorod region. The article presents the partial programs of preschool children developed and implemented in the practice of kindergartens of the Russian Federation: the partial program of spiritual and moral education of children is 5–7 years old “with a pure heart” (published by the Russian Word publishing house, posted in the federal register of educational programs of preschool Education in 2019), the partial program of the patriotic education of children 5–7 years old “Glory will not remain silentˮ. The content of the program is aimed at developing childrenʼs ideas about the Russian army, historical exploits of the defenders of the Fatherland and the education of moral-patriotic feelings and qualities of a person of an older preschool child.
Support of Games on Gender and Age Identification in Psychological and Pedagogical Habilitation of Preschoolers with Development Delay
Authors:   Institute of Special Education of the Ministry of Education of the Russian Federation, Vechkanova Irina G.
Published: July 2023

The article discusses the results of the study of the gender and age identification of preschoolers and, based on their consideration, suggests approaches to the organization of jointly distributed activities and a spatially developing play environment for habilitation and educational activities with children with different starting opportunities. The analysis of the results of the diagnosis of the process of sexual identification showed the role of social factors, the immediate environment in the formation of this process. The social factors of habilitation are revealed – play and communication during educational events involving children and adults (teachers and parents), as well as technological parameters of the educational situation, which are aimed at accompanying games on gender and age identification. The directions of the organization of the universal design of the educational environment and the implementation of tasks in games on social literacy/gender and age identification in the conditions of the “Educational eventˮ technology are described. Attention is drawn to social and museum-educational practices on the assimilation of roles, traditional cultural values, norms and rules of behavior in an inclusive society, civic identity, and historical memory by children with development delay.
Activities of the Class Teacher for the Diagnosis and Socialization of Children from Disadvantaged Families
Authors:   Novosibirsk State Pedagogical University, Shabanov Artyom G.
Published: July 2023

The article substantiates the importance of the activities of the class teacher for the diagnosis and socialization of children from disadvantaged families. Along with the main pedagogical activity, the class teacher carries out activities for the adaptation and socialization of children, interacting with the family, ensuring the solution of key tasks and solving issues of child upbringing. The main goals and objectives that the class teacher sets and solves for himself imply effective and regular interaction with the microsocium: parents, students, teachers, social educators and psychologists. The purpose of the article is to reveal the significance of the activities of the class teacher for the diagnosis and socialization of children from disadvantaged families, to show the directions of this activity in a mass school. The methodological basis of the article was the work of such authors as S. A. Belicheva, O. I. Volzhina, A. A. Rean, M. I. Rozhkov, V. M. Tseluiko, T. I. Shulga and others. The study is based on an activity approach, which sets the benchmark for including the child in a variety of areas of emotionally rich socially recognized and socially approved activities.
Integration of the Educational Space of the School: Potential and Prospects for Development
Authors:   Norilsk Children’s Art School named after Nikolai Pavlovich Loy, Eliseeva Svetlana V. , Romm Tatiana A. ,   Novosibirsk State Pedagogical University
Published: July 2023

The article deals with the problem of updating the educational strategy of the school by integrating additional education into the educational space of the school. The aim of the article is to substantiate the socio-pedagogical conditions of supplementary education integration into the educational space of the school. The research methodology is based on the system and network approaches. Evidence base served as the results of experimental work on approbation of the program “School of Cosmonautics” to integrate additional education in the educational space of the school, obtained through the methods of analysis, design, comparison, questioning, interviews, implementation of a system of measures, integrated in its content, comprehensive in types, forms and technologies of educational activities. Results of the study. The educational space of the school is considered as a pedagogically organized process, which on the basis of integration includes interested subjects of the educational environment, as well as the result of proactive activities of its internal and external elements, between which there are relations aimed at ensuring the implementation of the subjective position of the schoolchild. Within the integrative model of the educational space of the school there have been worked out educational programs in which individual components of activities could be combined with each other depending on the interests and abilities of students, school traditions, which allowed forming the content of all modules of the educational work program. The educational process was carried out in different environments and situations with the implementation of the principle of joint activities through the creation of socio-pedagogical conditions. As a result, the positive dynamics of the development of educational space, integrating and combining the potential of additional and general education, proved the presence of qualitative changes in the value orientations of schoolchildren. Conclusion. Experimental work has confirmed the effectiveness of additional education as an equal subject of integration processes in the educational space of the school to ensure the creative interaction of all subjects of educational space. The results of approbation of the program of integration of additional education in the educational space of the school confirmed its significance and reproducibility as an experience of expanding the possibilities of external and internal integration.
Features of the Development of the Personal Potential of Adolescents in the System of Additional Education of Physical Culture and Sports Orientation
Authors:   Kuzbass Center for Physical Education of Children, Smyshlyaev Dmitry V. , Kazin Eduard Mikhaylovich ,   Kemerovo State University, Kirichenko Vladimir V. ,   Secondary School № 36, Panina Tatyana S. ,   Russian State Specialized Academy of Arts, Koshko Natalya N. ,   Kuzbass Regional Center for Psychological, Pedagogical, Medical and Social Assistance “Health and Personal Development”
Published: July 2023

The purpose of the article is to identify the features of the development of the personal potential of adolescents in the system of additional education of physical culture and sports orientation on the basis of psychophysiological and psychological and social characteristics of adolescent students. The article actualizes the problem of creating organizational and pedagogical conditions during the implementation of the training cycle, adequate to the chosen specialization and regulatory and behavioral vegetative characteristics of students. Methodology. One of the central methodological problems considered in the article is the use of a complex of psychophysiological and psychological-social monitoring. The research of psychophysiological and psychological-social characteristics is carried out with the help of the program complex “School – Adaptation – Health”, which has an author’s certificate. The results of the study. The article presents materials reflecting the peculiarities of the development of the personal potential of adolescents; pedagogical tools, methods and technologies used taking into account the profile of sports specialization, individual typological, regulatory and behavioral mechanisms of the vegetative status of an individual. In conclusion, it is concluded that the development of the personal potential of adolescents is a process of complex influence of psychological and pedagogical factors determined by organizational and pedagogical conditions, the specifics of sports specialization of students based on the use of a health-oriented resource of an educational organization that provides increased physical fitness, psychological stability, individual, communication, improvement of moral and normative values, socialization of the individual, implemented taking into account age, psychophysiological (regulatory-typological) features.
The Formation of Tolerance in Older Preschool Children in Inclusive Education as a Psychological and Pedagogical Problem
Authors:   Novosibirsk State Technical University, Ogoltsova Elena G. , Paletskaia Tatyana V. ,   Novosibirsk State Pedagogical University
Published: July 2023

The article raises the problem of the need to form a tolerant attitude towards peers with disabilities in the framework of inclusive preschool education. The objective necessity of educating preschoolers in the spirit of tolerance in connection with the changes of recent decades in the economic, political, cultural life of the country and the actively developing system of inclusive education is substantiated. The purpose of the article is to theoretically and empirically investigate the process of forming a tolerant attitude towards children with disabilities in a preschool organization. Methodology. The analysis of the formation of a tolerant attitude towards peers with special health opportunities according to three criteria: cognitive, emotional and effective-practical. To do this, the following methods and techniques were used: observation; conversation; diagnostic methods for measuring the level of tolerant attitude towards peers with disabilities (a study of emotional interest in a peer on the test “Human Drawing” by K. Mahover, a study of subjective assessment of interpersonal relationships of a child (SOMOR), a sociometric study “Two houses” by T. D. Marcinkovskaya). The results of the study showed the need to search for effective pedagogical and psychological tools for the development of friendly and open interaction of older preschoolers with peers with disabilities. A plan of psychological and pedagogical measures for the further formation of a tolerant attitude towards peers with special health opportunities in the inclusive space of a preschool organization is proposed.
Sustainability Reporting, Foreign Ownership, Firm Value as a Function of Investment Opportunity Set
Authors: Hasanah Vanisa Nur , Nuraina Elva , Styaningrum Farida
Published: July 2023

Purpose: Firm value is one of the relevant company goals. Increasing firm value is supported by sustainability reporting and foreign ownership. The increase in firm value can be strengthened through a trusted Investment Opportunity Suitable to obtain returns that are attractive to investors and can be used as an injection of funds to implement sustainability reporting. Investigating the Investment Opportunity Set role in moderating the effect of sustainability reporting and foreign ownership on firm value. This study aims to investigate the Investment Opportunity Set in moderating the effect of sustainability reporting and foreign ownership on firm value.Method: This study uses a quantitative approach with independent variables on sustainability reporting and foreign ownership, the dependent variable on firm value, and the moderating variable. Investment Opportunity Set. This research is classified as non-experimental with cross-sectional data classification and documentation method. The research sample was 46 companies from 606 companies listed on the Indonesia Stock Exchange for 2013-2018. This study uses regression and Moderated Regression Analysis.Findings: The results showed that the Investment Opportunity Set does not moderate the effect of sustainability reporting on firm value. But Investment Opportunity Set moderate the influence of foreign ownership on firm value. Novelty: This study develops from previous research by proving that foreign ownership based on foreign investors is able to increase firm value. The study was conducted in all companies listed on the IDX that publish annual reports and sustainability reporting for the 2013-2018 period, this period is determined based on the first year of the change from the GRI G3 version to GRI G4 on May 22, 2013 which was launched in Amsterdam at the global sustainability reporting conference.
Sex chromosome aneuploidies and fertility: 47,XXY, 47,XYY, 47,XXX and 45,X/47,XXX
Authors: Rogol Alan D
Published: July 2023

The overall incidence of sex chromosome aneuploidies is approximately 1 per 500 live-born infants, but far more common at conception. I shall review the fertility aspects of the sex chromosome trisomies, XXY, XYY, and XXX, with special reference to the karyotype 45,X/47,XXX. Each has a ‘specific’ (but variable) phenotype but may be modified by mosaicism. Although the alterations in the hypothalamic–pituitary–gonadal axis are important (and discussed), the emphasis here is on potential fertility and if one might predict that at various epochs within an individual’s life span: fetal, ‘mini’-puberty, childhood, puberty, and adulthood. The reproductive axis is often affected in females with the 47,XXX karyotype with diminished ovarian reserve and accelerated loss of ovarian function. Fewer than 5% of females with Turner syndrome have the 45,X/47,XXX karyotype. They have taller stature and less severe fertility issues compared to females with the 45,X or other forms of Turner syndrome mosaicism. For the 47,XXY karyotype, non-obstructive azoospermia is almost universal with sperm retrieval by micro-testicular sperm extraction possible in slightly fewer than half of the men. Men with the 47,XYY karyotype have normal to large testes and much less testicular dysfunction than those with the 47,XXY karyotype. They do have a slight increase in infertility compared to the reference population but not nearly as severe as those with the 47,XXY karyotype. Assisted reproductive technology, especially micro-testicular sperm extraction, has an important role, especially for those with 47,XXY; however, more recent data show promising techniques for the in vitro maturation of spermatogonial stem cells and 3D organoids in culture. Assisted reproductive technology is more complex for the female, but vitrification of oocytes has shown promising advances.
Impaired colonic motility in high-glycemic diet-induced diabetic mice is associated with disrupted gut microbiota and neuromuscular function
Authors: Pei Ying , Wang Rui , Chen Wanyu , Yi Shulin , Huang Chen , Liang Shaochan , Cao Hongying , Xu Yifei , Tan Bo
Published: July 2023

Background

Similar to the high-fat diet (HFD), the high-glycemic diet (HGD) contributes to the development and progression of type 2 diabetes mellitus (T2DM). However, the effect of HGD on gastrointestinal motility in T2DM and its underlying mechanisms remain unclear.

Methods

Thirty C57BL/6J mice were randomly designated into the normal-feeding diet (NFD) group, HFD group, and HGD group. The plasma glucose, plasma insulin, and gastrointestinal motility were examined. Meanwhile, the tension of isolated colonic smooth muscle rings was calculated, and the gut microbiota was analyzed by 16s rDNA high-throughput sequencing.

Result

After 16 weeks of HGD feeding, obesity, hyperglycemia, insulin resistance, and constipation were observed in HGD mice. Autonomic contraction frequency of the colonic neuromuscular system and electrical field stimulation-induced contractions were reduced in HGD mice. On the contrary, neuronal nitric oxide synthase activity and neuromuscular relaxation were found to be enhanced. Finally, gut microbiota analysis revealed that Rhodospirillaceae abundance significantly increased at the family level in HGD mice. At the genus level, the abundance of Insolitispirillum increased remarkably, whereas Turicibacter abundance decreased significantly in HGD mice.

Conclusion

HGD induced constipation in obese diabetic mice, which we speculated that it may be related to neuromuscular dysmotility and intestinal microbiota dysbiosis.
Impact of vitamin B12 on the reproductive health of women with sickle cell disease: a narrative review
Authors: Agbalalah Tarimoboere , Robert Faith Owabhel , Amabebe Emmanuel
Published: July 2023

Sickle cell disease (SCD) poses an increased risk of infertility, pregnancy complications and maternal and perinatal mortality among women of reproductive age. This risk is particularly higher for women in sub-Saharan Africa, where the disease burden is highest and access to comprehensive health care is limited, as well as in other countries with a high SCD prevalence due to migration. Disease-modifying treatments for SCD could directly and indirectly harm the ovaries, potentially compromising the quality and quantity of existing oocytes. Therefore, it is essential to explore alternative interventions, such as nutritional modifications that are less harmful and cost-effective in order to improve reproductive outcomes and enhance the overall well-being of both mother and child in this population. Maintaining optimal levels of B12 may possibly provide benefits to the ovaries and pregnancy by decreasing homocysteine levels, increasing nitric oxide (NO) bioavailability and promoting antioxidant and anti-inflammatory activities. Individuals living with SCD are more susceptible to vitamin B12 (B12) deficiency. However, there is a lack of clinical data investigating the relationship between systemic levels of B12, its supplementation, and reproductive outcome measures in SCD women. Therefore, this review aims to examine the current evidence regarding the impact of SCD on female reproductive health and the role of B12 in the reproductive biology of women living with SCD.

Lay summary

Poor reproductive health is a concern for patients with sickle cell disease (SCD). SCD can lead to damage to the ovaries. Most of the therapies for sickle cell disease are toxic to the ovaries, expensive and unavailable to affected women, particularly those living in resource-poor areas such as sub-Saharan Africa. There is a need to seek less harmful and affordable interventions such as nutrition to improve reproductive outcomes for women with SCD who are of child-bearing age. Good levels of vitamin B12 have been found to maintain ovarian health and pregnancy. Patients with SCD have been reported to have a high risk of vitamin B12 deficiency, but the impact of B12 on reproduction in this group of women is yet to be evaluated. The review explores current evidence of the impact of both SCD and B12 on female reproduction.
A characterization for $B$-singular integral operator and its commutators on generalized weighted $B$-Morrey spaces
Authors: Hasanov J.J. , Ekincioglu I. , Keskin C.
Published: July 2023

We study the maximal operator $M_{\gamma}$ and the singular integral operator $A_{\gamma}$, associated with the generalized shift operator. The generalized shift operators are associated with the Laplace-Bessel differential operator. Our analysis is based on two weighted inequalities for the maximal operator, singular integral operators, and their commutators, related to the Laplace-Bessel differential operator in generalized weighted $B$-Morrey spaces.
Applications of uniform boundedness principle to matrix transformations
Authors: Sarıgöl M.A.
Published: July 2023

Using the uniform boundedness principle of Maddox, we characterize matrix transformations from the space $(\ell_{p}) _{T}$ to the spaces $m(\phi )$ and $n(\phi )$ for the case $1\leq p\leq \infty$, which correspond to bounded linear operators. Here $(\ell _{p})_{T}$ is the domain of an arbitrary triangle matrix $T$ in the space $\ell _{p}$, and the spaces $m(\phi )$ and $n(\phi )$ are introduced by W.L.C. Sargent. In special cases, we get some well known results of W.L.C. Sargent, M. Stieglitz and H. Tietz, E. Malkowsky and E. Savaş. Also we give other applications including some important new classes.
TEORÍA DEL CUERPO HUMANO EN ARISTÓTELES. SU BIOLOGÍA Y FILOSOFÍA TAL COMO APARECE EN DE PARTIBUS ANIMALIUM
Authors: Rodríguez López Juan
Published: July 2023

Toda la biología de Aristóteles es teleológica, esencialista, individualista, organicista y no evolucionista. Estos principios de explicación del ser vivo son aplicados por Aristóteles al cuerpo humano. La capacidad de pensar del ser humano determina la forma de su cuerpo y sus características: liberación del peso de la parte superior, manos y brazos con características especiales, nalgas carnosas y musculosas que le permiten estar de pie y sentado, piernas con músculos para estar de pie, senos en la parte delantera gracias a la liberación de la función de sustentación de los miembros superiores y que permiten proteger el tórax y sus órganos vitales, ausencia de cola que permite estar sentado, pies de mayor tamaño en comparación con los animales para facilitar la bipedestación y la marcha.  Por ello, el cuerpo humano no aparece realmente como modelo para el cuerpo de los animales sino como contrapartida, ya que lo que determina la forma de todo cuerpo vivo es su función (ergon) o forma de vivir, y la del ser humano para Aristóteles es vivir pensando, algo privativo del hombre, aunque comparta muchas otras capacidades cognitivas con los animales. Así, el deporte, en sus movimientos, es manifestación genuinamente humana y del pensamiento.
UNA CONSTATACIÓN ACTUAL DE LA VIGENCIA DEL IDEARIO OLÍMPICO EN LA EDUCACIÓN ESPAÑOLA A TRAVÉS DE UNA PROPUESTA EN EDUCACIÓN FÍSICA BASADA EN EL TRABAJO DE LA SOSTENIBILIDAD Y LOS PROYECTOS DE APRENDIZAJE-SERVICIO
Authors: Robles González Marta , Martínez Muñoz Luis Fernando
Published: July 2023

El presente artículo se sustenta sobre el contenido del Trabajo de Fin de Grado (TFG) presentado, el pasado curso académico, en la Facultad de Formación de Profesorado y Educación de la Universidad Autónoma de Madrid con motivo de la finalización del Grado en Ciencias de la Actividad Física y el Deporte.

Sus objetivos, su orientación y su propuesta didáctica para las clases de Educación Física evidencian que el ideario que supone la base del Olimpismo, es una propuesta que se sigue viendo interesante para que esté implícitamente vigente, presente y desarrollado en España por parte del profesorado de Educación Física dentro de dicha asignatura.

A través de un análisis exhaustivo del centro educativo de prácticas donde se desarrolló la materia del prácticum se pudieron detectar, entre otras circunstancias: 1) la falta de interés por parte del alumnado por la asignatura de Educación Física, 2) la necesidad de trabajar la resolución de problemas y conflictos en las sesiones de Educación Física y 3) la inactividad física del alumnado, muy presente durante los tiempos de recreo. 

Para subsanar dichas circunstancias, en el citado TFG se presentó una propuesta globalizada que combina el trabajo de los Objetivos de Desarrollo Sostenible a través de una programación didáctica para la Educación Física de 1º de Bachillerato y la puesta en marcha de proyectos de Aprendizaje-Servicio con carácter trimestral. Con ello se ha pretendido garantizar una EF de calidad, inclusiva, reflexiva y comprometida con el desarrollo sostenible, que viene a tener un paralelismo directo con los valores que propugna el ideario olímpico desde su creación.

El proyecto de Aprendizaje Servicio presentado se sitúa en el contexto de los recreos activos, favoreciendo la participación del alumnado de 1º de la Educación Secundaria Obligatoria del centro educativo de prácticas.
A proposito dei rapporti tra Persia e Mesopotamia: l'affaire Ciro-Nabonedo
Authors: D'Agostino F.
Published: July 2023

ISIMU
Recogiendo leña en los jardines de Samas
Authors: Da-Riva Muñoz M.
Published: July 2023

ISIMU
El final del discurso parabólico de Mateo: el escriba docto (MT 13, 51-52)
Authors: Carrón J.
Published: July 2023

ISIMU
La cuestión de eph'hoi en Romanos 5, 12
Authors: García Iglesias L.
Published: July 2023

ISIMU
Origini ed evoluzione del sistema centralizzato ad Arslantepe: dal tempio al palazzo nel IV millennio A.C.
Authors: Frangipane M.
Published: July 2023

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[es] LAS CULPAS DEL REY Y DE SU FAVORITO. EL PROCESO A ALONSO RAMÍREZ DE PRADO (1607-1608)
Authors: Mrozek Eliszezynski Giuseppe
Published: July 2023

El enorme poder alcanzado por el letrado Alonso Ramírez de Prado en los primeros ocho años (1598-1606) del reinado de Felipe III fue resultado directo del dominio que su patrón, el duque de Lerma, ejerció sobre la corte y el joven rey. El 26 diciembre de 1606, su repentina detención puso fin a una rutilante carrera política y empezó un proceso, descuidado por mucho tiempo por los historiadores, junto al conde de Villalonga, don Pedro Franqueza. A través del análisis de la documentación oficial relativa a la causa de Ramírez de Prado, el presente trabajo pretende ilustrar las diferentes razones de la acusación y, sobre todo, los argumentos de la defensa, encargada al hijo del acusado, don Lorenzo Ramírez de Prado. El veredicto de culpabilidad emitido al final del proceso parecía anular cualquier argumento de la defensa. Sin embargo, el debate sobre la responsabilidad del soberano con respecto al poder de sus favoritos continuó a lo largo de las décadas siguientes.PALABRAS CLAVE: Valimiento, Felipe III, Duque de Lerma, Visita, Alonso Ramírez de Prado, Lorenzo Ramírez de Prado, siglo XVII.THE FAULTS OF THE KING AND HIS FAVOURITE. THE TRIAL AGAINST ALONSO RAMÍREZ DE PRADO (1607-1608) The huge power achieved by the jurist Alonso Ramírez de Prado in the first eight years (1598-1606) of the reign of Philip III was a direct result of the supremacy of his patron, the Duke of Lerma, over the whole court and the young king. On December 26, 1606, his sudden arrest brought his brilliant career in politics to an end and started a trial, overlooked for a long time by historians in favor of the concurrent one against the Earl of Villalonga, Pedro Franqueza. Through the analysis of the official documentation about the case of Ramírez de Prado, the article aims to illustrate the many reasons of the prosecution and, above all, the arguments of the defence, entrusted to his son, Lorenzo Ramírez de Prado. The verdict of guilty returned at the end of the process seemed to erase any argument of the defence. However, the debate about the responsibilities of the sovereign in relation to the power of his favourites was destined to continue in the following decades.KEY WORDS: Favouritism, Philip III, Duke of Lerma, Visita, Alonso Ramírez de Prado, Lorenzo Ramírez de Prado, 17th century.
[es] LA CASA DE DON JUAN DE AUSTRIA EN EL GOBIERNO DE LA MONARQUÍA DE FELIPE IV
Authors: Trápaga Monchet Koldo
Published: July 2023

La forma en que se había configurado la Monarquía Hispánica durante los reinados de Carlos V y Felipe II quebró durante la segunda mitad del reinado de Felipe IV, por lo que se hizo necesaria la búsqueda de nuevas fórmulas para que la constitución de la Monarquía volviera a ser viable. El reconocimiento de don Juan de Austria, por parte de Felipe IV, se enmarca en éste proceso mediante el intento de recomposición de las relaciones de la corte de Madrid con los territorios periféricos de la Monarquía, por lo que la trayectoria política de don Juan durante los primeros años estuvo vinculada a la coyuntura y evolución global de la Monarquía. Así lo demuestra su periplo: Portugal, Flandes, gobierno de la Armada marítima para la recuperación de los presidios toscanos y, finalmente, Nápoles. Para llevar a cabo todas esas empresas políticas, Felipe IV situó a su alrededor a una serie de asesores y ministros que conformaron sus sucesivos servicios. En estas líneas se va a proceder al estudio de las mismas, con el fin de comprender el papel político desempeñado por don Juan antes de su llegada a Nápoles en la segunda mitad de 1647.PALABRAS CLAVE: Don Juan de Austria, Monarquía Hispánica, casas reales, territoriosTHE HOUSEHOLD OF DON JOHN OF AUSTRIA IN THE GOVERNMENT OF THE MONARCHY OF PHILIP IVThe way in which the Spanish Monarchy was organized during Charles V and Philip II reigns, broke up at the second half of Philip IV reign. So, there was necessary to find new alternatives with which the Spanish Monarchy returned to be viable. The recognition of don John of Austria by Philip IV, must be frame in this process, because it tried to recompose the relationships between the court of Madrid and the other European territories of the Monarchy. So, the earliest years of the political career of don John were connected with the political evolution of the whole Monarchy. His different political destinations prove this: Portugal, Flanders, the government of the royal navy to recover the Presidi Toscani and, finally, the reign of Naples. To obtain the success in all these territories, Philip IV situated around him different advisers and ministers whom composed his successives households. In this paper we will analyze them to understand the political role played by don John before his arrival in Naples at the second half of 1647.KEY WORDS: Don John of Austria, Spanish Monarchy, royals household, territories
[es] ENDEUDAMIENTO DINÁSTICO Y CRISIS FINANCIERAS EN TIEMPO DE LOS AUSTRIAS: LAS SUSPENSIONES DE PAGOS DE 1557-1627
Authors: Carlos Morales Carlos Javier
Published: July 2023

La historiografía modernista ha dedicado una constante atención a las relaciones entre gasto dinástico y crédito, fiscalidad y desarrollo político, hacienda y mercados monetarios. Al mismo tiempo, desde la historia económica también se han planteado diversas explicaciones sobre las crisis financieras, en particular, de Felipe II. En este artículo se analizan dichos trabajos y se expone la evolución de las suspensiones de pagos entre 1557 y 1627, con objeto de proponer un modelo explicativo basado en la integración diversos factores políticos, institucionales y económicos.PALABRAS CLAVE: endeudamiento, crisis financieras, Austrias, bancarrotas, finanzas.
Removal efficacy of toxic metals in leachate through micro-organisms isolated from the natural environment
Authors: Kocaman Ayhan , Savaş Burak Feyyaz , İşler Ceyhan Derya
Published: July 2023

Landfill leachate is a serious contaminant for groundwater and surface water because of its potentially toxic metal content. In many countries, leachate is discharged into the natural environment without treatment because of the high disposal cost. However, this environmental problem can be solved by microorganisms, as they can adsorb the contaminants or convert them into end products, and this is cost-effective. This study focused on determining bacteria capable of efficiently removing toxic metals from leachates. Therefore, bacteria were isolated from nature that have a high adsorption and resistance capacity to a number of toxic metals. This potential was achieved by Enterobacter hormaechei, Priestia aryabhattai, and Mycobacterium sacrum, among others. Their efficiency in removing toxic metals compared to raw leachate was Cd (78%, 67%, 78%), Ni (64%, 57%, 56%), Pb (99%, 75%, 76%), Cr (41%, 46%,19%), Co (45%, 60%, 40%), and Cu (80%, 80%, 60%), respectively. According to the results, these bacterial strains proved to be very effective in the treatment of toxic metals from leachate. Therefore, they are good candidates for the treatment of wastewater by bioremedial methods.
Thermo-mechanical pulping as a pretreatment for agricultural biomass as biochemical conversion
Authors: Gonzalez Ronalds , Jameel Hasan , Chang Hou-min , Treasure Trevor , Pirraglia Adrian , Saloni Daniel
Published: July 2023

The use of thermo-mechanical pulping (TMP), an existing and well known technology in the pulp and paper industry, is proposed as a potential pretreatment pathway of agriculture biomass for monomeric sugar production in preparation for further fermentation into alcohol species. Three agricultural biomass types, corn stover, wheat straw, and sweet sorghum bagasse, were pretreated in a TMP unit under two temperature conditions, 160 ºC and 170 ºC, and hydrolyzed using cellulase at 5, 10, and 20 FPU/g OD biomass. Wheat straw biomass was further pretreated at different conditions including: i) soaking with acetic acid, ii) longer steaming residence time (15 and 30 min), and iii) refined at lower disk gap (0.0508 and 0.1524 mm). Preliminary results showed that carbohydrate conversion increased from 25% to 40% when the TMP temperature was increased from 160 to 170 ºC. Carbohydrate conversion was relatively similar for the three biomasses under the same pretreatment conditions and enzyme loading. Acetic acid soaking and refining at a reduce disk gap increases carbohydrate conversion. Further studies within this technological field to identify optimum process and TMP conditions for pretreatment are suggested.