bluuebunny/crossref_metadata_2025 huggingface dataset:
Estilos de toma de decisiones intuitivo y racional e improvisación organizacional: ¿Influye la consciencia de los empleados acerca de la inteligencia artificial?
Authors: Vélez-Jaramillo Juan Daniel , Arias-Pérez José Enrique , López-Zapata Esteban
Published: November 2024

Los empleados están cada vez más conscientes del riesgo de ser reemplazados por la inteligencia artificial. Paradójicamente, ellos siguen siendo actores relevantes en la empresa cuando se trata de tomar decisiones para improvisar o dar respuesta en tiempo real a los cambios del entorno. El objetivo del artículo es evaluar el efecto moderador negativo de la consciencia de los empleados acerca de la inteligencia artificial (CEIA), en la relación entre los dos estilos de toma de decisiones: intuitivo (TDI) y racional (TDR), y la improvisación organizacional (IO). El modelo de investigación se testeó con datos recolectados mediante una encuesta realizada en empresas manufactureras y de servicios. Sorpresivamente, se encontró una moderación positiva de la CEIA en la relación entre TDI y IO. Este resultado permite controvertir algunos estudios previos que han advertido en reiteradas ocasiones sobre el peligro de la CEIA. Sin embargo, el resultado sugiere que este efecto es positivo solo cuando la empresa está bajo la presión de idear una respuesta en tiempo real a las exigencias del entorno.
A canção e o ensino de gêneros orais: reflexões didáticas a partir de “Geni e o Zepelim”, de Chico Buarque de Hollanda
Authors: Cardoso Francisco Octávio Ferreira , Magalhães Émerson Henrique Silva , Farias Melanie Mahah Carneiro Simardi , Abreu-Tardelli Lília Santos
Published: November 2024

O objetivo deste estudo é o de apresentar uma proposta didática para o trabalho com o gênero textual canção na sala de aula a partir de canções de Chico Buarque de Hollanda, nome de referência da Música Popular Brasileira (MPB). Foram analisadas três canções do compositor sob o quadro teórico-metodológico do interacionismo sociodiscursivo (Bronckart, 1999/2009; Machado; Bronckart, 2009; Schneuwly; Dolz, 2004), à luz de autores que se debruçam sobre a canção visando o ensino (Conforte; Dolz, 2023). As dimensões ensináveis, delimitadas em “Geni e o Zepelim” (1979), apontam a importância de aliar os elementos sonoros aos linguísticos e discursivos para uma abordagem holística do gênero, em propostas didáticas sensíveis às potencialidades da canção (e não apenas da letra) para o ensino de gêneros orais.
Africanos e suas línguas na história social do Brasil: notas de um percurso teórico-metodológico
Authors: Lima Ivana Stolze
Published: November 2024

Esse artigo tem como objetivo compartilhar parte da discussão travada pela instigante mesa “Línguas africanas e língua portuguesa no Brasil, em Angola e Moçambique – uma interface entre a história social, a literatura e a linguística”, no 69º Seminário do GEL, que ocorreu no Departamento de Linguística da USP, em julho de 2023. Coordenada por Márcia de Oliveira, e formada também por Rita Chaves e Alexander Cobbinah, tratou-se de uma rara e preciosa oportunidade de reunião de pesquisadores de áreas distintas em torno de um interesse comum, que de minha parte chamaria de uma visada sobre a experiência de africanos no processo de colonização e escravização articulado pela língua portuguesa. A minha apresentação, aqui sintetizada, retoma alguns artigos já publicados, nos quais as referências bibliográficas e documentais detalhadas estão disponíveis. Procurando apontar o percurso da pesquisa, focalizo inicialmente o problema da língua nacional no Brasil oitocentista e em seguida discuto a questão das línguas africanas no contexto colonial. Um olhar para a história social do Brasil sensível aos africanos e suas línguas permite aprofundar o conhecimento da história dos povos africanos em diáspora
Protecting arable land, reducing pollution and increasing efficiency: promoting the implementation of crop fallow rotation
Authors: Ye Ma
Published: November 2024

Currently, the quality and quantity of agricultural resources have entered a period of hard constraints, agricultural environmental pollution has become increasingly serious, and the quality of arable land has been declining.In order to promote the sustainable development of agriculture and explore the sustainable use of arable land, this study takes China as an example to analyse the impacts, mechanisms and regulating effects of crop fallow rotation on the ecological efficiency of arable land.Firstly,This study selected the panel data of Chinese provinces and municipalities directly under the central government from 2010 to 2020, and firstly used the non-expectation Super-SBM model to measure the ecological efficiency of arable land in each region of China;Secondly, the effects and differences in effects of crop fallow rotation on the ecological efficiency of arable land were analysed using an asymptotic differences in differences model with two-way fixed effects;Finally, the mechanism of crop fallow rotation and the external influencing factors in the implementation process were explored through regulating analysis and mechanism analysis.The regression results indicate that crop fallow rotation can significantly contribute to the ecological efficiency of arable land, and the results still hold after a series of robustness tests;Differential analyses indicate that crop rotation promotes ecological efficiency of arable land more than crop fallow;The analysis of the regulating effect shows that the small peasant economy reduces the effect of crop fallow rotation, while the government's support to agriculture and the cultivation of new agricultural management subjects can enhance the effect of crop fallow rotation;Mechanism analysis shows that crop fallow rotation can reduce the redundancy level of input factors, reduce agricultural carbon emissions and surface pollution to promote the ecological efficiency of arable land.Based on this, the study makes the following recommendations:1.Strengthen the promotion of crop fallow rotation,implemented with crop rotation as the main focus, with crop fallow as the secondary focus;2.Strengthen the cultivation of new agricultural management subjects, and promote the moderate-scale operation of agriculture;3.Improve the efficiency of the use of arable land, and actively promote agricultural carbon emissions reduction and the treatment of surface source pollution.
Eight patients with inflammatory myofibroblastic tumor treated with rigid bronchoscopy
Authors: Jeong Byeong-Ho , Ho Rong Lih , Lee Ho Yun , Han Joungho , Kim Hojoong
Published: November 2024

Background
Pulmonary inflammatory myofibroblastic tumor (IMT) accounts for 0.04–0.7% of all lung tumors, and endobronchial IMT accounts for only 10% of all pulmonary IMTs. Little is known about the therapeutic outcomes of rigid bronchoscopy for endobronchial IMT. Here, we report a case series of eight patients with endobronchial IMT underwent rigid bronchoscopy.
Methods
We retrospectively analyzed eight patients with endobronchial IMT between January 2004 and December 2023.
Results
The median age of our patients was 36 years, and 62.5% were male. Dyspnea was the predominant symptom in cases where the tumor was centrally located (n = 6), whereas hemoptysis was the predominant symptom in peripherally located tumors (n = 2). Most cases had high contrast enhancement and a tumor stalk without bronchial wall invasion on computed tomography (CT) and bronchoscopy. Complete endoscopic resection and laser cauterization via rigid bronchoscopy were possible in five patients. There were only two cases in which tumors remained after the procedure, requiring additional treatment (chemotherapy and surgical resection, respectively). In one patient, surgical resection was performed three weeks after the procedure, and the surgical specimen was free of residual tumor. There was no mortality during the median follow-up duration of 18.8 months.
Conclusions
Endoscopic resection and laser cauterization using rigid bronchoscopy appear to be a safe and effective alternative treatment modality to surgery for patients with endobronchial IMT.
The Poké ball sign in a mature ovarian cystic teratoma
Authors: Alfonso-Cerdán Sheila , Villalba-Cortés Alejandro , Menso María Magdalena , Martínez-Ruiz Nicolás , Novel-Olivé Berta , Pernas-Canadell Juan Carlos
Published: November 2024

We present the case of a 32-year-old woman with a mature ovarian cystic teratoma exhibiting the "Poké ball" sign, pathognomonic for this tumour.
Application of EOS based on machine learning method on CFD study of rapid hydrogen refueling process
Authors: Seo Hyo Min , Park Byung Heung
Published: November 2024

Currently, commercially operated hydrogen fuel cell electric vehicles (FECVs) store hydrogen as highly compressed gas form to increase volumetric energy density. To provide a refueling time similar to that of internal combustion engine vehicles (ICEVs), hydrogen refueling stations (HRSs) should supply gaseous hydrogen into FECVs up to high pressure (35 MPa or 70 MPa) in a relatively short time. The refueling process of rapidly filling compressed gas within a confined volume of the storage tank is inevitably accompanied by an increase in temperature. However, the refueling process should be carried out under limited conditions considering the physical safety of the storage tank. Modeling the refueling process under the theoretical basis is useful for understanding the gas filling phenomenon and finding the optimal refueling strategy. In particular, the CFD research method which considers the flow of fluid in a tank offers the local temperature changes inside a storage tank as well as the average temperature. The CFD research is conducted by combining a model representing the fluid properties and a model describing the flow characteristics. Therefore, an appropriate combination of models should be examined before simulating the refueling process of an actual FECVs that requires time and cost that cannot be overlooked. In this study, the hydrogen refueling process is simulated using three equations of state (EOSs) and five turbulent models and, then, the results are compared and quantitively analyzed using experimental data. Experiments of filling type III tank of 74 L up to 35 MPa within 1 min have been chosen to make the assumption of axial symmetry for CFD model valid. Comparing the three EOSs (SRK, PR, ML), it is found that it is possible to improve accuracy and reduce calculation time when using ML EOS which has been developed to describe the behavior of hydrogen. Among the five turbulence models (yPlus, k-ε, realizable k-ε, low Reynolds k-ε, and k-ω) generally used in CFD research, the k-ε and the realizable k-ε model show satisfactory results on the reproduction of mean and local thermal behaviors and calculation time.
HPLC-MS/MS Monitoring and Health Risk Assessment of Carbosulfan and its Metabolites in Date Palm Fruit (Phoenix dactylifera)
Authors: Morsi Rana , Ghoudi Kilani , Elabyad Basant , Kadoura Zaina , Zeidane Hind , Al-Meetani Bayan , Meetani Mohammed A.
Published: November 2024

This study investigated residual levels of carbosulfan and its metabolites in date palm fruit in the UAE using HPLC-MS/MS and QuEChERS method. The method demonstrated excellent linearity (R2 > 0.998), low LOD (0.001–0.04 𝜇g/kg) and LOQ (0.003-0.1 𝜇g/kg), and high recoveries (92%-103%) with low RSD values (1–9%). The matrix effect was negligible (-16.43–17.09%), and uncertainty measurements did not exceed the 50% limit. Carbosulfan was present in all samples, exceeding its MRL in 46% of the samples. Carbofuran and 3-hydroxycarbofuran exceeded their MRL in 4.87% and 40% of the samples, respectively, while 3-ketocarbofuran levels were below the MRL. Dibutylamine was found in 82% of the samples, with an average concentration of 9.01 µg/kg. The health risk assessment for children and adults showed that all HQ values were below the safety limit of 1.0, indicating that date consumption poses no adverse health risks for either adults or children.
Towards a Unified Fold-Cusp Model for Bond Polarity Scaling: Electron Rearrangements in the Pyrolytic Isomerization of Cubane to Cyclooctatetraene
Authors: Ayarde-Henríquez Leandro , Guerra Cristian , Pérez Patricia , Chamorro Eduardo
Published: November 2024

Context
This study meticulously examines the criteria for assigning electron rearrangements along the intrinsic reaction coordinate (IRC) leading to bond formation and breaking processes during the pyrolytic isomerization of cubane (CUB) to 1,3,5,7-cyclooctatetraene (COT) from both thermochemical and bonding perspectives. Notably, no cusp-type function was detected in the initial thermal conversion step of CUB to bicyclo[4.2.0]octa-2,4,7-triene (BOT). Contrary to previous reports, all relevant fluxes of the pairing density must be described in terms of fold unfolding. The transannular ring opening in the second step highlights characteristics indicative of a cusp-type catastrophe, facilitating a direct comparison with fold features. This fact underscores the critical role of density symmetry persistence near topographical events in determining the type of bifurcation. A fold-cusp unified model for scaling the polarity of chemical bonds is proposed, integrating ubiquitous reaction classes such as isomerization, bimolecular nucleophilic substitution, and cycloaddition. The analysis reveals that bond polarity index (BPI) values within the [0, 10− 5]au interval correlate with cusp unfolding, whereas fold spans over a broader [10− 3, ∞) au spectrum. These insights emphasize that the cusp polynomial is suitable for describing chemical processes involving symmetric electron density distributions, particularly those involving homolytic bond cleavages; in contrast, fold characterizes most chemical events.
Methods
Geometry optimization and frequency calculations were conducted using various DFT functionals. In line with recent findings concerning the rigorous application of BET, the characterization of bond formations and scissions via unfoldings was carried out by carefully monitoring the determinant of the Hessian matrix at all potentially degenerate CPs and their relative distance. The computed gas-phase activation enthalpies strongly align with experimental values, stressing the adequacy of the chosen levels of theory in describing the ELF topography along the IRC. The BPI was determined using the methodology proposed by Allen and collaborators.
Phase 1 Study of AYP-101 (Soybean Phosphatidylcholine): Safety, Pharmacokinetics, and Lipid Profile Effects for Reducing Submental Fat
Authors: Lee Hyun Joon , Jiang Xu , El-Aty A. M. Abd , Jeong Ji Hoon , Chung Jae-Yong
Published: November 2024

Background
Excessive submental fat under the chin is a known aesthetic concern because of its negative impact on facial appearance and psychological well-being. AYP-101 is a newly developed injectable agent containing 93% soybean phosphatidylcholine (SPC) designed to reduce submental fat. We conducted a phase 1 study to evaluate the safety, pharmacokinetic (PK), and lipid profile effects of AYP-101.
Methods
This study was a randomized, double-blind, placebo-controlled, single-dose, two-cohort trial. Participants were randomized into groups receiving 250 mg of AYP-101, 500 mg of AYP-101, or placebo at a 9:9:8 ratio across both cohorts. Safety was assessed through standard clinical evaluations. Blood samples were collected up to 144 h postdose in cohort 1 and up to 48 h postdose in cohort 2. The PK parameters were calculated via noncompartmental analysis.
Results
All 26 randomized subjects completed the study. There were 72 solicited adverse drug reactions (ADRs) reported by 20 subjects, all of which were mild. The most common ADRs were injection site pain and bruising. No clinically significant differences in safety, PK, or lipid profiles were observed between the dose groups.
Conclusions
AYP-101 appears to be a safe candidate for treating submental fat, with localized reactions and no systemic exposure at single subcutaneous doses of up to 500 mg.
Trial registration:
ClinicalTrials.gov NCT05476094
Sellar and perisellar meningiomas: effects on pituitary function in a Spanish observational study
Authors: Guerrero-Pérez Fernando , Biagetti Betina , Fano Miguel Paja , Menéndez-Torre Edelmiro Luis , Rivero Gonzalo , Dios Elena , Hanzu Felicia Alexandra , Rojas-Marcos Patricia Martín , Irigaray Ana , Rodríguez María Dolores Moure , García-Centeno Rogelio , Fernández Laura González , Enseñat Joaquim , Mora Mireia , Villar-Taibo Rocío , García Isabel M. Ortiz , Araujo-Castro Marta , Gándara Carmen , García María Dolores Ollero , Tenorio-Jiménez Carmen , Novo-Rodríguez Cristina , Civantos Soralla , Simó-Servat Andreu , Aulinas Anna , Asla Queralt , Cordido Fernando , Novoa-Testa Iría , Xifra Gemma , Ayala-Conte María , Zamarrón Álvaro , Berrocal M Isabel García , Iglesias Pedro
Published: November 2024

Purpose
Studies focused on the effects of sellar and/or perisellar (S/PS) meningiomas on pituitary function are scarce. We evaluate the clinical characteristics, therapeutic outcomes, and the effects that S/PS meningiomas and their treatments have on pituitary function.
Methods
A multicenter and retrospective study of patients with S/PS meningiomas attended in 20 tertiary Spanish centers.
Results
171 patients, 129 (75.4%) females, with median age of 61.5 [51–71] years were analyzed. At presentation, 118 (69.1%) had visual disturbance, 66 (38.6%) headache, 46 (26.9%) cranial nerve palsy and 35 (25.7%) hypopituitarism. Median tumor diameter was 29 [22-35.5] mm and cavernous sinus infiltration was detected in 99 (59.3%) of which 77 (77.8%) had Knosp grades 3 or 4. As initial treatment, 134 (78.4%) underwent surgery, 25 (14.6%) received radiotherapy and 12 (7%) were clinically and radiologically monitored. Among operated patients, gross total resection (GTR) was achieved in 45 (33.6%), whereas in 89 (66.4%) the tumor was incompletely removed. Overall median follow-up was 5.7 [2.9–9.2] years. After treatments, hypopituitarism increased significantly in the whole series (n = 86, 53.1%) respect to diagnosis (n = 35, 25.7%), p < 0.001. Development of hypopituitarism was not associated with surgery extension (subtotal or GTR), histological subtype, type of radiotherapy or radiation dose received.
Conclusions
S/PS meningiomas affect the pituitary function in 25% of the cases. However, after the implementation of treatments, hypopituitarism prevails in more than 50% of the cases. They are relatively large tumors and often locally invasive, and GTR is achieved in only one third of the cases.
Risk factors for wound complications after associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) compared to repeated liver resection - a propensity score matching analysis
Authors: Khajeh Elias , Sabetkish Nastaran , Ramouz Ali , Werba Alexander , Klotz Rosa , Michalski Christoph W. , Mehrabi Arianeb , Pianka Frank
Published: November 2024

Aim: Sufficient liver function is crucial in extracellular matrix growth, hemostasis, and wound healing. Repeated abdominal surgery is a known risk factor for the development of wound complications. This study aimed to evaluate this high-risk constellation in patients undergoing associated liver partition and portal vein ligation for staged hepatectomy (ALPPS) and repeated liver resections (RLR) in comparison to single liver resection (SLR).
Method: Forty patients who underwent ALPPS between 2011 and 2020 were evenly matched with patients undergoing RLR or SLR (n=40 per group) using propensity scores. Postoperative outcomes were compared and factors associated with wound complications were analyzed.
Results: Postoperative wound complications were significantly more frequent in ALPPS group (p=0.001). The reoperation rate was not significantly different between the three groups (p=0.143). However, surgical reintervention due to wound complications occurred more frequently in the ALPPS group in relation to RLR and SLR (17.5% vs. 7.5% and 5% respectively). Length of stay was significantly longer in the ALPPS group (p=0.033). ALPPS was an independent risk factor for postoperative wound complication (OR= 8.55, 95% CI:1.07-68.44, p=0.043). Risk factor analysis identified age ≥60 years (OR=27.64, 95% CI:3.09-246.75, p=0.003), BMI≥30 kg/m2 (OR=30.21, 95% CI:3.35-271.83, p=0.002), and low postoperative albumin levels (OR=168.41, 95% CI:7.76-3651.18, p=0.001) as independent predictors of postoperative wound complications after major liver resection.
Conclusion: Patients undergoing ALPPS and RLR are faced with a high risk of developing wound complications. Older age, obesity, a history of previous abdominal surgery, and a decreased postoperative albumin level were independent risk factors for wound complications.
Emotional and Cognitive Experiences of Undergraduate Dental Students during Initial Orthodontic Prescriptions: A Mixed-Methods Study
Authors: Lakshmikantha Hemanth Tumkur
Published: November 2024

The emotional and cognitive experiences of undergraduate dental students have been studied as they prescribe their first orthodontic appliance. Data were gathered from nine participants via a mixed-method approach. The data analysis revealed some cognitive biases, such as anchoring and confirmation biases, and that participants had high confidence levels and moderate stress and anxiety levels. The important themes associated with academic and interpersonal elements, such as cognitive overload, emotional resilience, support and mentorship, decision-making strategies, and effective communication, have been observed in qualitative studies. The study revealed that the role of mentors can help them in decision-making, as they receive guidance and support. The significance of cognitive and emotional training in the dental curriculum was identified in this study, as it improved the students’ ability to practice in the clinic. These findings are particularly relevant to dental education in Fuji and the border Pacific regions. This implies the necessity of a personalized support system that can help address the challenges faced by students. A detailed understanding of these experiences can help educational institutions cultivate professionals with knowledge, compassion, skills, patient care, and so on. This study contributes to the literature on dental education in the Pacific region and provides recommendations for the development of curriculum and student support.
A novel pathogenic DICER1 variant is associated with heriditary multinodular goiter in an Argentine family as evidenced by clinical, biochemical and molecular genetic analysis
Authors: Targovnik Héctor M. , Barh Debmalya , Papendieck Patricia , Adrover Ezequiela , Gallo Ariel M. , Chiesa Ana , Silva Wanderson Marques , Azevedo Vasco , Rivolta Carina M.
Published: November 2024

DICER1 syndrome is an autosomal-dominant disorder that results in malignant or benign tumors. A number of distinct pathogenic germline and somatic variants have been identified as causing multinodular goiter (MNG). The purpose of the present study was to identify and characterize the genetic cause underlying the familial form of MNG through a whole-exome sequencing (WES) analysis in an Argentine family with three affected siblings. Clinical, biochemical and molecular genetics as well as bioinformatics analysis were performed. A novel heterozygous variant in the DICER1 gene was identified in the proband patient by WES. The variant was a single guanine deletion at nucleotide position 2,042 (NM_177438.3:c.2042del) resulting in a frameshift at amino acid 681 with a putative premature stop codon [NP_803187.1:p.Gly681ValfsTer4]. Family segregation analysis showed that his affected sister and his affected brother also were heterozygous for same variant, whereas the father was a healthy heterozygous carrier of the variant and the healthy mother harbor only wild-type alleles in the DICER1 gene. We have also observed that the frameshift variant does not interfere with the pre-mRNA splicing of the exon 13. In addition, two clinically relevant heterozygous variants, not associated with thyroid disease, were also identified in index sibling using the Franklin platform, a frameshift [NP_000234.1:p.Thr55AsnfsTer49] in the MEFV gene (familial mediterranean fever) and a missense [NP_004530.1:p.Ala422Thr] in the NARS1 gene (neurodevelopmental delay and ataxia). In conclusion, in the present study we have identified a novel frameshift variant corresponding to NP_803187.1:p.Gly681ValfsTer4 in the DUF 283 domain of DICER1. The results were in accordance with previous observations confirming the genetic heterogeneity of DICER1 syndrome. Moreover, the identification of this variant in the unaffected father substantiates the hypothesis of incomplete/reduced penetrance.
Claudin-1 as a potential marker of stress-induced premature senescence in vascular smooth muscle cells
Authors: Gadecka Agnieszka , Buko Tomasz , Janiszewska Dorota , Koblowska Marta , Iwanicka-Nowicka Roksana , Kossowska Helena , Bojakowski Krzysztof , Mosieniak Grażyna , Bielak-Zmijewska Anna
Published: November 2024

Cellular senescence, a permanent state of cell cycle arrest, can result either from external stress and is then called stress-induced premature senescence (SIPS), or from the exhaustion of cell division potential giving rise to replicative senescence (RS). Despite numerous biomarkers distinguishing SIPS from RS remains challenging. We propose claudin-1 (CLDN1) as a potential cell-specific marker of SIPS in vascular smooth muscle cells (VSMCs). In our study, VSMCs subjected to RS or SIPS exhibited significantly higher levels of CLDN1 expression exclusively in SIPS. Moreover, nuclear accumulation of this protein was also characteristic only of prematurely senescent cells. ChIP-seq results suggest that higher CLDN1 expression in SIPS might be a result of a more open chromatin state, as evidenced by a broader H3K4me3 peak in the gene promoter region. However, the broad H3K4me3 peak and relatively high CLDN1 expression in RS did not translate into protein level, which implies a different regulatory mechanism in this type of senescence. Elevated CLDN1 levels were also observed in VSMCs isolated from atherosclerotic plaques, although this was highly donor dependent. These findings indicate that increased CLDN1 level in prematurely senescent cells may serve as a promising cell-specific marker of SIPS in VSMCs, both in vitro and ex vivo.
Pregnancy-associated acute kidney injury as a hidden driver of Chronic kidney disease in developing countries
Authors: Meena Priti , Das Paromita , Auradkar Anagha , Moideen Adel , Bhargava Vinant , Kasturi Umang , Singla Vidhi , PANDA SANDIP , Mohan Krithika
Published: November 2024

Introduction:
Pregnancy-related AKI (PR-AKI), has profound maternal and fetal implications, including high mortality and long-term risks such as the development of chronic kidney disease (CKD). This systematic review aims to evaluate the burden of CKD owing to PR-AKI cases during follow-up in developing countries, particularly India.
Methods:
A systematic search of PubMed, Embase, and Cochrane databases was performed for Indian studies published between 2000 and June 2024. We included cross-sectional, retrospective, and prospective cohort studies that reported the incidence of PR-AKI, subsequent CKD, and dialysis dependency in Indian cohorts during follow-up. Details of etiology of PRAKI, and adverse fetal and maternal outcomes were also recorded. Only studies that provided follow-up kidney outcomes were considered.
Results:
A total of 25 studies comprising 2,306 participants were included in the analysis. The incidence of PR-AKI ranged from 1–12%. Sepsis was the most common cause of PR-AKI, accounting for up to 78% of cases, followed by hypertensive disorders, obstetric haemorrhage, and tropical etiologies. Hemodialysis was required in 20–85% of patients. CKD development during follow-up was observed in 12.8–35% of cases, with up to 30% remaining dialysis-dependent. Maternal mortality ranged from 2.5–34%, while perinatal mortality reached as high as 67.3%. Pre-term delivery rates varied between 13.9% and 58%.
Conclusions:
Up to one-third of PR-AKI patients may develop CKD and remain dialysis-dependent during follow-up. PR-AKI significantly impacts both maternal and fetal morbidity and mortality. Early prevention and prompt management by healthcare professionals are critical to improving outcomes in PR-AKI.
RhoB regulates prostate cancer cell proliferation and docetaxel sensitivity via PI3K-AKT signaling pathway
Authors: Sheng Tiantian , Su Hang , Yao Lu , Qu Zhen , Liu Hui , Shao Wenjuan , Zhang Xiangyu
Published: November 2024

Docetaxel is the first line treatment method for castration-resistant prostate cancer (CRPC). RhoB plays important role in prostate cancer metastasis and PI3K-AKT signaling pathway. RhoB involves in regulation of cytoskeleton reassembly, cell migration, focal adhesion (FA) dynamics. CRISPR/Cas9 gene editing technique was utilized to knock out the RhoB gene in prostate cancer cells, and was confirmed by using T7 endonuclease I (T7EI) and Sanger sequencing. Epithelial–mesenchymal transition (EMT) process was enhanced by RhoB knockout (KO), IC50 value of docetaxel towards PC-3 cells with RhoB KO decreased. Migration and invasion of prostate cancer cells were enhanced when the RhoB gene was knocked out, and these were inhibited when the gene was overexpressed. But, cell cycle of prostate cancer cells was not affected by the RhoB gene status. RNA seq was conducted on PC-3 cells which were overexpressed or knock out RhoB gene. The RNA seq results indicated that RhoB may regulate focal adhesion, ECM receptor interaction, and PI3K-AKT signaling pathway and further influence the EMT process, migration, and invasion of prostate cancer cells. We also found that RhoB overexpression activate PI3K-AKT signaling when PC-3 cells were treated with low concentration of DTXL (50 nM, 72 h), suggesting RhoB overexpression decreased DTXL cytotoxicity towards prostate cancer cells via PI3K-AKT signaling activation.
Navigating Healthcare and Public Benefits in NC: Perspectives of Undocumented Latina Women with U.S.-Born Children
Authors: Raffa Brittany J , Higgins Isabella CA , Montiel Catalina , Stafford Allison McCord , Cholera Rushina
Published: November 2024

Background and Objectives:
Mixed documentation status Latino families face unique barriers to accessing healthcare and public benefits. We examined the experiences of undocumented Latina mothers in North Carolina and the role of anti-immigrant policies and rhetoric in their decisions to access care and public benefits for themselves and their U.S. born infants.
Methods
We conducted a qualitative descriptive study to describe Latina mothers’ experiences seeking care for themselves and their infants during the perinatal period. We used emergency Medicaid at delivery as a proxy to identify undocumented mothers with U.S. born infants. Twenty semi-structured audio interviews were conducted in Spanish via Zoom. We used rapid qualitative content analysis for timely, action-oriented analysis. Rapid qualitative analysis uses visual displays, such as matrices, to connect and analyze findings.
Results
Five themes emerged: Confusion around public benefit eligibility and complicated enrollment processes; Fears around Supplemental Nutrition Assistance Program (SNAP); Cost as the most influential barrier to healthcare; Positive experiences with language support and respectfulness of providers; “Making it work” with the help of social support systems.
Conclusions
Postpartum undocumented mothers of US-born children experience several barriers to NC Medicaid and public benefit enrollment, including complicated application processes, costs, and immigration-related fear. Further research and policy advocacy is needed to assess how to improve enrollment rates and provide education on eligibility for families during the postpartum period.
Assessment of Practices and Factors Associated With Solid Waste Management Among Institutions in Arada Sub Cityaddis Ababa, Ethiopia, 2023
Authors: Getachew Mussie , Fasil Nebiyou , Yekoye Abere
Published: November 2024

Problem Statement: Addis Ababa is getting polluted due to an increase of wastes management practice problem; dwellers of Addis Ababa continue to dispose wastes along the roads, in ditches, rivers, open spaces, avenues, etc. of the city. This situation is exacerbated in slums like Arada sub-city where households and institutions cannot make use of garbage collection facilities. This study indicates what the communities solid waste disposal system will look like especially in the institutions and also what are the things that need to be improved with the removal system they are currently using in terms of suggesting how good it should be.
Objectives: To assess Practices and factors associated with solid waste management among institutions in Arada sub city Addis Ababa, Ethiopia, 2023
Methods:The study was conducted in 350 institutions of arada sub city of Addis Ababa. Cross-sectional study design was used to conduct the study. the data was collected using a pre-tested and interviwed questionnaireusing a google form. Stratified random sampling employed to address the objective of this study. The data was coded, cleaned and analyzed using Statistical Package for Social Studies (SPSS)V.25.
Results: The majority of the institutions, 251 (71.7%) solid waste management practices are improper.the multivariable analysis showed that there was statistically significant (p < 0.05) association improper waste management practice and factors such as, attitude p-value 0.01, (AOR = 2.7,95% CI = 1.49-5.2)), awareness P-value (0.04) AOR = 2.4, 95%CI= 1.2-4.6)), type waste such as, textile related waste p-value (0.03) AOR = 4.06,95%CI = 1.5-10.8)) and type of institutions as well.
Conclusion & Recommendation: Practices of solid waste management among institution were poor. awareness, attitude, type of institution and type of waste were associated with improper waste management practice. attitude and awareness should be enhanced at institutions to level on proper waste management practice.
Traffic Classification in SDN-Based IoT Network using Two-Level Fused Network with Self-Adaptive Manta Ray Foraging
Authors: A. Mohammed
Published: November 2024

The rapid expansion of IoT networks, combined with the flexibility of Software-Defined Networking (SDN), has significantly increased the complexity of traffic management, requiring accurate classification to ensure optimal quality of service (QoS). Existing traffic classification techniques often rely on manual feature selection, limiting adaptability and efficiency in dynamic environments. This paper presents a novel traffic classification framework for SDN-based IoT networks, introducing a Two-Level Fused Network integrated with a self-adaptive Manta Ray Foraging Optimization (SMRFO) algorithm. The framework automatically selects optimal features and fuses multi-level network insights to enhance classification accuracy. Network traffic is classified into four key categories—delay-sensitive, loss-sensitive, bandwidth-sensitive, and best-effort—tailoring QoS to meet the specific requirements of each class. The proposed model is evaluated using publicly available datasets (CIC-Darknet and ISCX-ToR), achieving superior performance with over 99% accuracy. The results demonstrate the effectiveness of the Two-Level Fused Network and SMRFO in outperforming state-of-the-art classification methods, providing a scalable solution for SDN-based IoT traffic management.
Research on movie rating based on BERT-base model
Authors: Ning Weijun , Wang Fuwei , Wang Weimin , Wu Haodong , Zhao Qihao , Zhang Tianxin
Published: November 2024

The advent of the Internet has led to the ascendance of film reviews as a crucial point of reference for users when making decisions about which films to watch. Furthermore, film reviews play a pivotal role in content recommendation systems for producers and platforms. It is therefore evident that the accurate classification of film reviews holds significant practical value. The traditional manual classification methods are characterised by a high level of time consumption, a considerable labour input, and a susceptibility to subjective biases. Conversely, the application of automated classification through the use of deep learning models has emerged as an efficacious solution to this issue. Among these models, the BERT model, distinguished by its bidirectional encoder architecture, demonstrates particular proficiency in contextual comprehension and semantic extraction. However, it is constrained in its ability to capture long-range dependencies and local features when processing extended texts. In order to address these challenges, this study puts forward a series of proposed improvements to the BERT model. In particular, absolute positional encoding is substituted with dynamic positional bias encoding within the attention mechanism, thereby enhancing the model's capacity to process diverse positional information. Additionally, a dynamic weighted fusion pooling strategy is introduced, which integrates average pooling, max pooling, and self-attention pooling in order to enrich the feature extraction process. Moreover, the model's capacity for generalisation is enhanced through the implementation of Easy Data Augmentation (EDA) techniques and the introduction of noise into the training data. The experimental results demonstrate that the improved BERT model achieves a 0.65% improvement in the F1 score and a 0.83% increase in accuracy, thereby validating the efficacy of the proposed modifications.
Advanced State Estimation Methods for Lithium-Ion EV Batteries: A Kalman Filter and MLP Hybrid Approach
Authors: S Mohana Devi. , Bagyaveereswaran V.
Published: November 2024

The proliferation of electric vehicles has advanced battery technology; yet safety concerns have emerged related to mechanical, electrical, or thermal problems. An effective Battery Management System is crucial for enhancing battery performance, particularly regarding State of Charge and State of Health. Research has concentrated on examining sensor malfunctions in batteries to avert problems such as overcharging and overheating. Techniques like as voltage measurement, coulomb counting, and Kalman filtering are employed for state of charge estimate. To overcome these limitations, the proposed work utilizes the Extended Kalman Filter (EKF), which can handle the non-linear characteristics often exhibited by sensor readings and fault behaviours. The EKF algorithm involves initialization, prediction, and correction phases, allowing for accurate state estimation based on measurements. For SOH estimation, the NASA battery dataset, which includes various battery conditions across different temperatures, is analysed using a modified Multi-Layer Perceptron (MLP) regression process. This modified MLP employs a gradient shift bias adjustment technique to minimize error rates, effectively adjusting the model's weights for better SOH estimation. The findings demonstrate enhanced performance in State of Charge (SOC) and State of Health (SOH) estimates for Root Mean Square (RMS) and Mean Squared Error (MSE).
Tumor Immune Microenvironment in Adenoid Cystic Carcinoma of the Lacrimal Gland: Relationship with Histopathology and Prognosis
Authors: Zhang Yi , Sun Jie , Bi Yingwen , Cai Rongrong , Zhang Rui , Ren Hui , Meng Fengxi , Qian Jiang
Published: November 2024

Purpose:
To quantitatively investigate the pathological subtypes of lacrimal gland adenoid cystic carcinoma (LGACCs), the tumor immune microenvironment in each pathological subtype, and the relation to survival.
Methods:
In this retrospective study, the tumor subtype was determined by H&E staining. Multiplex immunochemistry was performed to define specific immune cells. The tumor immune microenvironment (TIME) was sketched by sequential image scanning and reconstructed by a cytometry platform.
Results:
Thirteen patients of LGACCs showed a mixture of different pathological subtypes with varied percentages. The cribriform was the most common subtype, taking an overall percentage of 39%. The rest of the pathological subtypes were tubular (19%), basaloid (17%), cribriform and tubular mixture (C+T) 14%. The sclerosing and comedocarcinomic subtypes were the least seen in LGACC, taking a percentage of 11% altogether. Patients with cribriform dominant component had better overall survival than the non-cribriform dominant patients. Patients with basaloid dominant component had worse clinical outcomes than the non-basaloid dominant ones. The TIME showed high immunogenicity in the tumor margin but declined in the tumor areas. Pathological subtypes rather than individual differences determined the TIME phenotype. The cribriform subtype possessed more immune cell infiltration than other pathological subtypes.
Conclusions:
LGACC is composed of multiple subtypes with different percentages, which is related to the prognosis. TIME pattern in LGACC varied among different pathological subtypes, which could indicate novel strategies in immunotherapy.
Statistical sedimentary aspects of collapsed volcanic edifices along Pacific subduction zones.
Authors: bernard karine
Published: November 2024

Using Google Earth imagery and published data on volcanoes worldwide, several examples of volcanic debris avalanche deposits have been compared to characterize the dynamics of mass flow and matrix transformation during glacial and interglacial periods. Sedimentological studies of these deposits help to correlate the spatial and temporal distribution of collapsed edifices with the stratigraphy and textural variations of the matrix. Parameters such as percentage of matrix, mean grain size, ratio of matrix sand to gravel and other statistical sedimentary parameters have been calculated to characterize the matrix breccias in relation to the spatio-temporal variability of the mass flow deposits. Factors such as quaternary erosion, nival surface conditions and high intensity rainfall contribute to the transformation of the reworked avalanche deposits into debris flows. The sedimentary characteristics of volcanic debris avalanche deposits are influenced by the profile shape, volcanic area and slope gradient of the collapsed edifices, which are related to the critical stability and quaternary cyclic evolution of the stratovolcanoes. Empirical equations have been developed to propose a co-genetic evolution of volcanic avalanche deposits in terms of their spatio-temporal distribution, morphological variations of the collapsed edifices, and climatic changes. Similar correlations between quaternary occurrence, matrix percentage, matrix/gravel ratio, and median grain size show a positive association with the obliquity of the Earth's axis and the precession of the equinoxes. These results highlight the importance of semi-quantitative sedimentological analyses of deposits from collapsed volcanic edifices in refining our understanding of subsequent hazardous flows .
Impact of consolidation tumor size of part-solid adenocarcinoma on survival–A propensity score matching analysis
Authors: Hino Haruaki , Maru Natsumi , Utsumi Takahiro , Matsui Hiroshi , Taniguchi Yohei , Saito Tomohito , Kouda Katsuyasu , Murakawa Tomohiro
Published: November 2024

Purpose: Recent evidence indicates that the consolidation tumor size of part-solid adenocarcinoma does not have prognostic value unlike that of pure-solid adenocarcinoma. We aimed to analyze the impact of consolidation tumor size on postoperative survival in part-solid adenocarcinomas.
Methods: This retrospective study analyzed data of 375 patients with part-solid adenocarcinomas who underwent surgery at our institute between 2006 and 2021. The patients were grouped into the low (>0–≤0.5, n=187) and high (>0.5 to <1, n=188) consolidation-to-tumor ratio groups. Clinical characteristics and survival stratified by consolidation-to-tumor ratio were analyzed using propensity score matching for consolidation tumor size.
Results: A larger consolidation tumor size significantly correlated with higher consolidation-to-tumor ratio (r2=0.56, P<0.0001) and larger pathological invasive size (r2=0.41, P<0.0001). Male sex and high consolidation tumor size were significant negative risk factors for overall survival in the unmatched cohort. The 5-year overall survival rates in the low/high consolidation-to-tumor ratio groups were 95.2%/85.2% (P=0.008), respectively, in the unmatched cohort and 93.0%/83.2% (P=0.10), respectively, in the matched cohort, demonstrating a diminished significant survival difference.
he result of the competing risk analysis using the cumulative incidence of cancer or non-cancer death curves. The 5-year cumulative incidence of cancer-death rates were 0% (95% CI, NA–NA) and 5.57% (95% CI, 2.10–11.70) in the low and high CTR groups, respectively, with significant difference (P=0.01). In contrast, the 5-year cumulative incidence of non-cancer-death rates were 4.72% (95% CI, 1.40–11.10) and 9.44% (95% CI, 4.50–16.50) in the low and high CTR groups, respectively, with no significant difference (P=0.18). These results indicate a significant difference in cancer mortality the between the two groups.
Conclusions: The consolidation tumor size may affect overall survival and possibly reflect tumor growth activity, being consistent with TNM 8th edition, in part-solid adenocarcinomas.
Resilience and Social Influences Towards Prevention of Adolescent Pregnancies in High School Students in Addis Ababa, Ethiopia
Authors: Berehe Fisseha , Honest Faniswa
Published: November 2024

Adolescent pregnancy in Ethiopia is a major health concern because of its association with higher morbidity and mortality for both mother and child. The purpose of this study was to investigate resilience and social influences in proactively preventing adolescent pregnancies among high school adolescents. A quantitative cross-sectional survey was conducted using adolescent resilience questionnaires (ARQ) in two systematic selected high schools in Ethiopia. Statistical analysis of the completed 790 adolescent resilience questionnaires (ARQ) was done using Statistical Package for Social Sciences software (SPSS) version 23. The study results showed high scales ranking of (< 50%) by respondents on 80% of social influences dimensions pertaining to the family, peers, school and the community in terms of their availability, non-availability, connectedness or not connected. High scores of social influences correlated with high levels of resilience in adolescents. Multivariate logistic regression showed adolescents who are 18–19 years of age and school grade 11 more likely to demonstrate resilience (p < 0.05). The study suggests that adolescents with enough community support and self-assurance are likely to become resilient when faced with hardships.