bluuebunny/crossref_metadata_2025 huggingface dataset:
Enzymatic Hydrolysis of Meat Waste for a Circular Economy
Authors: Angulo M. , Márquez M. C.
Published: February 2023

This work demonstrates the possibility of implementing a technology that allows profitable value to be drawn from the meat waste from retail stores. Protein hydrolysate, collagen and fatty acids were recovered from meat waste through enzymatic hydrolysis using a mixture of enzymes: a protease (Alcalase) and a lipase (Resinase). Enzymatic hydrolysis was studied by response surface methodology (RMS). Four independent variables were used to study the response variables. The analysis showed that all factors including protease/proteinic substrate ratio, lipase/lipidic substrate ratio, pH and temperature had a significant effect on responses of recovery of a protein hydrolysate, collagen, and fatty acids. From RSM-generated models, different optimum conditions were obtained depending on the product to be recovered. The economic study showed that operating profit depends on the operating conditions but that, in suitable conditions, it is four or more times higher than that obtained in the transformation of meat waste into meal for animal feed (the current destination of the meat waste that does not go to landfill). Consequently, the enzymatic treatment proposed for meat waste in this work is highly recommendable to maintain a circular economy for this biodegradable waste.
Bacteriosis en bananito
Authors:   Ministerio de Agricultura y Desarrollo Rural, Bogotá (Colombia),   Corporación Colombiana de Investigación Agropecuaria, (Colombia)
Published: February 2023

Una buena desinfección de la zona y elementos al momento de utilizar prácticas culturales le ayudarán a prevenir enfermedades en el bananito.
An Intervention to Increase Condom Use Among Users of Sexually Transmitted Infection Self-sampling Websites (Wrapped): Protocol for a Randomized Controlled Feasibility Trial
Authors: Newby Katie , Kwah Kayleigh , Schumacher Lauren , Crutzen Rik , Bailey Julia V , Jackson Louise J , Bremner Stephen , Brown Katherine E
Published: February 2023

Background

Reducing the rates of sexually transmitted infections (STIs) among young people is a public health priority. The best way to avoid STIs from penetrative sex is to use a condom, but young people report inconsistent use. A missed opportunity to intervene to increase condom use is when young people access self-sampling kits for STIs through the internet. The potential of this opportunity is enhanced by the increasing numbers of young people being tested through this route every year in England. Hence, in a cocreation by young people, stakeholders, and researchers, Wrapped was developed––a fully automated, multicomponent, and interactive digital behavior change intervention developed for users of STI self-sampling websites, who are aged 16-24 years.

Objective

This paper is a protocol for a feasibility randomized controlled trial (fRCT). The fRCT seeks to establish whether it is feasible to run a randomized controlled trial to test the effectiveness and cost-effectiveness of Wrapped. Wrapped aims to reduce the incidence of STIs through increasing correct and consistent use of condoms among users of STI self-sampling websites, who are aged 16-24 years.

Methods

A 2-arm parallel-group randomized fRCT of Wrapped plus usual care, compared to usual care only (basic information on STIs and condom use), with a nested qualitative study. A minimum of 230 participants (aged 16-24 years) are recruited from an existing chlamydia self-sampling website. Participants are randomized into 1 of 2 parallel groups (1:1 allocation). Primary outcomes are the percentage of users recruited to the fRCT and the percentage of randomized participants who return a chlamydia self-sampling kit at month 12. Additionally, besides chlamydia positivity based on biological samples, surveys at baseline, month 3, month 6, and month 12, are used to assess condom use attitude, behavioral capability, self-efficacy, and intention, along with details of any partnered sexual activity and condom use, and health economic data. Nested qualitative interviews with trial participants are used to gain insight into the factors affecting recruitment and attrition.

Results

Recruitment to the fRCT began in March 2021 and was completed in October 2021. Data collection was completed in December 2022.

Conclusions

This feasibility study will provide data to inform the design of a future-definitive trial. This work is timely given a rapid rise in the use of internet testing for STIs and the sustained high levels of STIs among young people.

Trial Registration

ISRCTN Registry ISRCTN17478654; http://www.isrctn.com/ISRCTN17478654

International Registered Report Identifier (IRRID)

DERR1-10.2196/43645
Prediction Models for Sleep Quality Among College Students During the COVID-19 Outbreak: Cross-sectional Study Based on the Internet New Media
Authors: Zheng Wanyu , Chen Qingquan , Yao Ling , Zhuang Jiajing , Huang Jiewei , Hu Yiming , Yu Shaoyang , Chen Tebin , Wei Nan , Zeng Yifu , Zhang Yixiang , Fan Chunmei , Wang Youjuan
Published: February 2023

Background

COVID-19 has been reported to affect the sleep quality of Chinese residents; however, the epidemic’s effects on the sleep quality of college students during closed-loop management remain unclear, and a screening tool is lacking.

Objective

This study aimed to understand the sleep quality of college students in Fujian Province during the epidemic and determine sensitive variables, in order to develop an efficient prediction model for the early screening of sleep problems in college students.

Methods

From April 5 to 16, 2022, a cross-sectional internet-based survey was conducted. The Pittsburgh Sleep Quality Index (PSQI) scale, a self-designed general data questionnaire, and the sleep quality influencing factor questionnaire were used to understand the sleep quality of respondents in the previous month. A chi-square test and a multivariate unconditioned logistic regression analysis were performed, and influencing factors obtained were applied to develop prediction models. The data were divided into a training-testing set (n=14,451, 70%) and an independent validation set (n=6194, 30%) by stratified sampling. Four models using logistic regression, an artificial neural network, random forest, and naïve Bayes were developed and validated.

Results

In total, 20,645 subjects were included in this survey, with a mean global PSQI score of 6.02 (SD 3.112). The sleep disturbance rate was 28.9% (n=5972, defined as a global PSQI score >7 points). A total of 11 variables related to sleep quality were taken as parameters of the prediction models, including age, gender, residence, specialty, respiratory history, coffee consumption, stay up, long hours on the internet, sudden changes, fears of infection, and impatient closed-loop management. Among the generated models, the artificial neural network model proved to be the best, with an area under curve, accuracy, sensitivity, specificity, positive predictive value, and negative predictive value of 0.713, 73.52%, 25.51%, 92.58%, 57.71%, and 75.79%, respectively. It is noteworthy that the logistic regression, random forest, and naive Bayes models achieved high specificities of 94.41%, 94.77%, and 86.40%, respectively.

Conclusions

The COVID-19 containment measures affected the sleep quality of college students on multiple levels, indicating that it is desiderate to provide targeted university management and social support. The artificial neural network model has presented excellent predictive efficiency and is favorable for implementing measures earlier in order to improve present conditions.
Effectiveness of a Continuous Remote Temperature Monitoring Program to Reduce Foot Ulcers and Amputations: Multicenter Postmarket Registry Study (Preprint)
Authors: Shih Chia-Ding , Scholten Henk Jan , Ripp Gavin , Srikanth Kirthana , Smith Caileigh , Ma Ran , Fu Jie , Reyzelman Alexander M
Published: February 2023

BACKGROUND

Neuropathic foot ulcers are the leading cause of nontraumatic foot amputations, particularly among patients with diabetes. Traditional methods of monitoring and managing these patients are periodic in-person clinic visits, which are passive and may be insufficient for preventing neuropathic foot ulcers and amputations. Continuous remote temperature monitoring has the potential to capture the critical period before the foot ulcers develop and to improve outcomes by providing real-time data and early interventions. For the first time, the effectiveness of such a strategy to prevent neuropathic foot ulcers and related complications among high-risk patients in a real-world commercial setting is reported.

OBJECTIVE

This study aims to evaluate the effectiveness of a real-world continuous remote temperature monitoring program in preventing neuropathic foot ulcers and amputations in patients with diabetes.

METHODS

In this retrospective analysis of a real-world continuous remote temperature monitoring program, 115 high-risk patients identified by clinical providers from 15 geographically diverse private podiatry offices were analyzed. Patients received continuous remote monitoring socks as part of the program. The enrollment was based on medical necessity as decided by their managing physician. We evaluated data from up to 2 years before enrollment and up to 3 years during the program. The primary outcome was the rate of wound development. Secondary outcomes included amputation rate, the severity of the foot ulcers, and the number of visits to an outpatient podiatry clinic after enrolling in the program.

RESULTS

We observed significantly lower rates of foot ulceration (relative risk reduction [RRR] 0.68; 95% CI 0.52-0.79; number needed to treat [NNT] 5.0; P<.001), less moderate to severe ulcers (RRR 0.86; 95% CI 0.70-0.93; NNT 16.2; P<.001), less amputations (RRR 0.83; 95% CI 0.39-0.95; NNT 41.7; P=.006), and less hospitalizations (RRR 0.63; 95% CI 0.33-0.80; NNT 5.7; P<.002). We found a decrease in outpatient podiatry office visits during the program (RRR 0.31; 95% CI 0.24-0.37; NNT 0.46; P<.001).

CONCLUSIONS

Our findings suggested that a real-world continuous remote temperature monitoring program was an effective strategy to prevent foot ulcer development and nontraumatic foot amputation among high-risk patients.
Texto, comunicação, interação: considerações sobre a possível delimitação dos conceitos
Authors: Travaglia Luiz Carlos
Published: February 2023

A proposição de que existem fronteiras entre texto, interação e comunicação implica que temos três fenômenos distintos e há fronteiras entre eles. Além disso, se são distintos, que características distinguem esses três fenômenos? Como eles se relacionam e por meio de quê? O que marca ou confunde suas fronteiras? Este trabalho busca responder a essas questões, explicitando as características distintivas de texto, interação e comunicação e o que os superpõe, fazendo com que suas fronteiras sejam fluidas e difusas. Comentamos ainda rapidamente sobre a existência de particularidades dessa distinção nas mídias sociais.
Uma análise textual dos efeitos patêmicos em campanhas publicitárias educativas
Authors: Rodrigues Francisca Tarciclê Pontes , Oliveira Rafael Lima de , Silveira Geana Barbosa da
Published: February 2023

O contexto de pandemia do coronavírus impulsionou a criação de inúmeras campanhas publicitárias educativas que, entre seus propósitos comunicativos, visam orientar a população quanto aos modos de prevenção à Covid-19. Essas campanhas, por vezes, passaram a investir no apelo às emoções com o intuito de sensibilizar a população quanto à temática. Este artigo, partindo de uma articulação teórica entre a Teoria Semiolinguística, de Patrick Charaudeau, e a Linguística Textual, desenvolve uma análise textual dos efeitos patêmicos. Para isso, assume as reflexões sobre patemização, de Charaudeau (2010a), mas defende, em consonância com Oliveira (2020), que, além de analisadas pelo contrato de comunicação, as estratégias de patemização sejam vistas sob o prisma das estratégias de textualização, especialmente os processos referenciais (CAVALCANTE; MARTINS, 2020). A análise aponta para o papel decisivo da introdução e, principalmente, da recategorização dos referentes negociados no texto na construção de uma encenação patemizante, além das focalizações dêiticas, que cumprem a função de engajar o interlocutor nessa encenação. Para isso, o locutor estrategicamente dispõe os referentes apoiando-se nas crenças que ele supõe serem assumidas pelo interlocutor.
A(s) mulher(es) no Direito Civil brasileiro e sua evolução à luz da Terminologia Diacrônica
Authors: Curti-Contessoto Beatriz
Published: February 2023

A mulher, enquanto ser que se constitui nas e pelas relações socialmente estabelecidas, pode ter sua identidade relacionada a diferentes concepções jurídicas em diferentes momentos da história do Direito, que expressam características de sua(s) identidade(s) segundo o que instituem as leis de um país. Propomo-nos, então, realizar um estudo terminológico-diacrônico a respeito das transformações do termo mulher e das unidades sintagmáticas formadas a partir dele em 11 leis brasileiras que compõem o LBCorpus, partindo de 1889, ano em que houve a Proclamação da República nesse país, e chegando a 2002, quando foi publicado o nosso Código Civil mais recente. Neste estudo, dedicamo-nos, especificamente, em verificar de que modo se deu a evolução semântica e lexical desses termos por meio de suas ocorrências no referido corpus e qual a relação entre essa evolução e o(s) papel(is) instituído(s) à mulher na sociedade brasileira do final do século XIX ao início do século XXI no âmbito do Direito. Para tanto, adotamos os pressupostos da Terminologia Diacrônica (TD) e da Teoria Sociocognitiva da Terminologia (TST), relacionados a alguns conceitos relativos à pós-modernidade, especialmente os que dizem respeito à concepção de identidade.
Mulheres caluniadas no Sergipe oitocentista: uma abordagem léxico-semântica da terminologia de puta
Authors: Pereira Augusto Petronio
Published: February 2023

Este artigo é um recorte da nossa dissertação de mestrado, cujo objeto são ofensas verbais proferidas contra mulheres no século XIX em Sergipe. Nossos esforços partem dos fatos históricos que deram contexto ao nosso corpus, os processos-crimes de ofensas verbais (doravante PC-OV), e se concentram no léxico ofensivo sob a ótica da lexicologia social (MATORÉ, 1953) e da semântica cognitiva (LAKOFF; JOHNSON, 2002 [1980]). O objetivo é apresentar uma análise léxico-semântica de uma das ofensas verbais (doravante OV) mais recorrente no levantamento dos autos, o epíteto puta, presente em cinco dos dez PC-OV oitocentistas sergipanos, cuja vítima da ofensa é a mulher. Nosso estudo tem como contexto histórico o Sergipe oitocentista, que se caracteriza pelo patriarcalismo, estratificação e desigualdade social (NUNES, 2006). Esse cenário possibilita estabelecer um quadro social sobre a mulher e suas condições, impostas por aquela sociedade (FALCI, 2006). A noção de OV, como uma terminologia do léxico, atravessa língua e cultura como resultado de tradução do mundo (BIDERMAN, 2001) e está presente nas interações humanas de todos os tempos (SHOEMAKER, 2000). Com isso, analisamos as OV como um léxico ofensivo na perspectiva dos Modelos Cognitivos Idealizados (LAKOFF, 1987) e da constituição prototípica e categorial (ROSCH, 1978).
A produção de sentido por meio de metáforas multimodais em capas de revistas que versam sobre política no Brasil
Authors: Santos Zaira Bomfante , Paiva Francis Arthuso , Gualberto Clarice Lage
Published: February 2023

A nossa existência, como seres sociais, é marcada pela linguagem como ferramenta para a produção de sentido que, ininterruptamente, se manifesta nas relações sociais. Assim, pronunciamos o mundo de diversas formas e modos que ganham materialidade por meio de textos. Nesse sentido, este trabalho apoia-se na perspectiva sociossemiótica da linguagem (KRESS, 2010) e busca discutir a noção de textura como recurso semiótico (DJONOV; VAN LEEUWEN, 2011) para a produção de metáforas multimodais, considerando as qualidades e potencialidades das texturas táteis e visuais das sensações corporificadas do leitor (GAIARSA, 2021). Nossas reflexões acenam para análise de capas de revistas brasileiras que versam sobre política no período do impeachment da presidente Dilma até as eleições presidenciais de 2018, buscando compreender como elas se constituem, quais qualidades e aspectos potenciais de significação de texturas táteis e visuais são utilizadas para produção de metáforas multimodais. Os resultados apontam que, além de comunicar com o seu público – classe social privilegiada brasileira –, as capas refletem o hábito desses grupos elitizados em estigmatizar classes populares a partir da deformação grotesca dos seus representantes políticos por meio de recursos de representação de textura.
Produção de cards para o Instagram: uma proposta de Letramento Inclusivo
Authors: Dantas Daniel Soares , Corrêa Adriana Moreira de Souza
Published: February 2023

Este trabalho é uma reflexão que envolve o letramento digital e a multimodalidade na orientação do trabalho de tradução para a Língua Brasileira de Sinais, a Libras, por meio de lives transmitidas pelo perfil no Instagram da Escola Estadual de Ensino Fundamental e Médio Dom Moisés Coelho (Cajazeiras – PB). Neste contexto, o objetivo foi produzir diretrizes para o desenvolvimento dessas lives transmitidas pelo Instagram da escola, a fim de propor caminhos metodológicos para a viabilização da mensagem em duas línguas – Libras e Português – para tornar as transmissões acessíveis aos usuários desses sistemas linguísticos. As análises são baseadas nos conceitos de multimodalidade (ROJO, 2012, RIBEIRO, 2018); nas orientações técnicas para a tradução e interpretação (FEBRAPILS, 2020), e em outras discussões sobre multimodalidade e inclusão. A metodologia adotada configura-se como uma pesquisa-ação, de abordagem qualitativa e natureza descritiva. Como resultado, desenvolvemos um conjunto de 10 cards explicativos com diretrizes para realização de uma live, considerando o público de surdos e ouvintes. Para isso, o foco da investigação consiste de elementos técnicos – som, imagem, enquadramento, posicionamento de câmera – e outros elementos multimodais como a participação ao vivo através do chat e simultaneidade de línguas no ambiente digital. Essa orientação técnico-metodológica busca esclarecer ao público como diretrizes para a transmissão de lives podem favorecer a inclusão da pessoa surda na rede social Instagram.
A identidade de Cerro Largo (RS) a partir de dois monumentos da Praça da Matriz
Authors: Oppermann Miranda Rafaela , Ferreira Dias Ana Beatriz
Published: February 2023

Neste artigo, discutimos a identidade de Cerro Largo, uma cidade do interior do estado do Rio Grande do Sul (RS), por meio da análise de dois monumentos localizados na Praça da Matriz, a qual está situada no centro do espaço urbano. Trata-se de uma pesquisa de natureza qualitativa e exploratória, que problematiza a constituição do espaço urbano, tendo o enunciado como unidade de análise. Para a realização deste trabalho, mobilizamos pressupostos teóricos e metodológicos dos estudos bakhtinianos. Com vistas à compreensão de sentidos produzidos pelas materialidades selecionadas para análise, buscamos exercitar a metodologia de cotejamento entre textos, tal como preconizada por Geraldi (2012). Assim sendo, percebemos que a colonização alemã e a religião católica resultam socialmente valoradas. Também notamos que os monumentos estabelecidos naquela que é considerada a principal praça de Cerro Largo operam na (con)formação de uma identificação para a cidade apoiada nos elementos étnico e religioso, bem como que grupos sociais outros, mesmo que não evidenciados nessa identidade, constituem-na desde o exterior. Concluímos que a identidade projetada para a cidade a partir dos dois monumentos consiste em uma expressão de base colonialista.
Metáforas multimodais na retórica neopentecostal
Authors: Martins Erik Fernando Miletta , Souza Marcela Costa de
Published: February 2023

O objetivo deste artigo é analisar a relação entre metáfora e gestualidade na retórica neopentecostal, a fim de explorar o peso dessa relação como parte fundamental das estratégias de adesão às crenças centrais da Teologia da Prosperidade. Os dados são constituídos por metáforas multimodais associadas a essas crenças e extraídas de cultos religiosos ministrados pelos líderes das duas igrejas neopentecostais brasileiras mais influentes no campo religioso: a Igreja Universal do Reino de Deus e a Igreja Internacional da Graça de Deus. Do ponto de vista teórico, o artigo ancora-se junto aos estudos sociocognitivos do texto, campo fértil para um diálogo entre a Linguística Textual e a Linguística Cognitiva. Para descrição, classificação e quantificação dos dados, orientamo-nos pela tipologização dos gestos adotada por Miranda e Mendes (2014) e por Kendon (2004). A análise quantitativa indicou, entre outras coisas, predominância de metáforas conceptuais orientacionais, processo ilustrado na análise qualitativa de um excerto de cada um dos cultos. As metáforas multimodais, quando empregadas diante da emergência de conceitos ligados à Teologia da Prosperidade, cumprem importante função na construção referencial desses conceitos para o público-alvo dessa retórica. São, portanto, estratégias argumentativas de grande relevância à retórica neopentecostal, ao fornecerem elementos visuais às metáforas verbais mais elementares dessa teologia.
Review: Controlled Release of Analgesics
Authors: Singh Rashi , Bharati Ashwini
Published: February 2023

Abstract: The regulated release of medication into the patient provided by the patch makes transdermal drug delivery superior to other methods of pharmaceutical administration. The medication instantly enters the bloodstream through the skin. Low concentration in the blood and high concentration on the patch. The usage of polymers is successful in achieving analgesics' sustained release. To evaluate effectiveness, in vitro and in vivo investigations were conducted. Due to the advantages that biodegradable polymers have over other materials in use, there is currently a huge demand for them. A biodegradable preparation of polymer and active ingredient is made for wound healing with a synthetic porous drug-loaded top layer and a spongy collagen sublayer. This method of analgesic delivery is slowly progressing among people and would further require few advancements as it is completely contrast to the conventional forms.
Functional zoning of park territories in large cities of Belarus: development of methods and quality assessment
Authors: Silin Ruslan V. , Korbut Elena E.
Published: February 2023

Introduction. In Belarus, some urban parks are less attractive for visitors and need reconstruction due to the new requirements for specific types and conditions of recreation, which have changed over the last decades due to the influence of factors triggered by a change in the economic model of societal development. The task of functional zoning is solved when a park reconstruction project is developed. Decisions concerning the recreational and other areas have an important impact on park design stages and play an important role in developing comfortable park environments. The purpose of the study is to build and validate a methodology for assessing the quality of functional zoning of urban parks using quantifiable factors.

Materials and methods. Quantifiable factors, that have a considerable impact on the comfort of park environments, were identified using an integrated approach. A planogram-based graphic-analytical method was used to assess the intensity of this impact. To identify the criteria for assessing the quality of park zoning, publicly available design guidelines and master plans of parks were analyzed. Information about current functional zoning of parks was obtained at the preliminary stage of the study by examining satellite images downloaded from the Google Earth Engine Explorer resource; this information was subsequently clarified using surveying methods.

Results. A need to take into account a number of quantifiable factors, influencing the comfort of environments, accompanies the process of developing a functional zoning pattern for multifunctional urban parks. Hence, we had an idea to develop a methodology for the functional zoning quality assessment. For this purpose, a system of criteria for assessing the quality of functional zones and an assessment methodology were developed. The methodology stems from the fact that a planogram of influence of various factors on park territories represents a nonzero two-dimensional matrix, which helps perform mathe­matical summation operations in furtherance of a given set of criteria. The new methodology was used to assess the quality of current functional zoning of urban parks in eight large Belarusian cities.

Conclusions. The methodology developed for the quality assessment of current functional zoning of urban parks confirms the validity of design solutions, and it can be used at the pre-project stage to improve the validity of solutions in the process of developing architectural and planning concepts of parks aimed at their reconstruction. It can also serve as a component of comprehensive assessments of comfort in the park environments when management decisions are made in terms of recreational areas.
Towards Local Community Involvement in Students’ Science Learning: Perspectives of Students and Teachers
Authors: Suero Montero Calkin , Oliveira Leite Lais
Published: February 2023

The European Commission calls for schools to move towards becoming open to their communities, integrating external social, civil, and expert stakeholders into authentic learning experiences’ development alongside teachers and students, particularly in terms of science education. However, little research or practical implementation has been reported on how community actors could participate in the development of such curricular learning activities. In this study, we present an implementation of the open science schooling (OSS) approach to science learning, where community involvement in the development of science missions takes a vital role. During the study, students developed science missions related to local societal issues that interested them in collaboration with their teachers and community experts, with frequent hands-on investigations outside their classrooms or laboratories, in five European countries and Israel. Questionnaires with quantitative and qualitative questions concerning students’ and teachers’ views and perspectives about implementing science education using OSS were administered after the participants finished their science missions. The results indicate the effectiveness of the OSS approach to science learning involving the community from both students’ and teachers’ perspectives. This study is a step towards supporting schools in becoming active agents of change through the implementation of contextualized learning experiences alongside external stakeholders.
Purifying teleportation
Authors: Roszak Katarzyna , Korbicz Jarosław K.
Published: February 2023

Coupling to the environment typically suppresses quantum properties of physical systems via decoherence mechanisms. This is one of the main obstacles in practical implementations of quantum protocols. In this work we show how decoherence effects can be reversed/suppressed during quantum teleportation in a network scenario. Treating the environment quantumly, we show that under a general pure dephasing coupling, performing a second teleportation step can probabilistically reverse the decoherence effects if certain commutativity conditions hold. This effect is purely quantum and most pronounced for qubit systems, where in 25 % of instances the decoherence can be reversed completely. As an example, we show the effect in a physical model of a qubit register coupled to a bosonic bath. We also analyze general d-dimensional systems, identifying all instances of decoherence suppression. Our results are proof-of-concept but we believe will be relevant for the emerging field of quantum networks as teleportation is the key building block of network protocols.
Performance analysis of quantum repeaters enabled by deterministically generated photonic graph states
Authors: Zhan Yuan , Hilaire Paul , Barnes Edwin , Economou Sophia E. , Sun Shuo
Published: February 2023

By encoding logical qubits into specific types of photonic graph states, one can realize quantum repeaters that enable fast entanglement distribution rates approaching classical communication. However, the generation of these photonic graph states requires a formidable resource overhead using traditional approaches based on linear optics. Overcoming this challenge, a number of new schemes have been proposed that employ quantum emitters to deterministically generate photonic graph states. Although these schemes have the potential to significantly reduce the resource cost, a systematic comparison of the repeater performance among different encodings and different generation schemes is lacking. Here, we quantitatively analyze the performance of quantum repeaters based on two different graph states, i.e. the tree graph states and the repeater graph states. For both states, we compare the performance between two generation schemes, one based on a single quantum emitter coupled to ancillary matter qubits, and one based on a single quantum emitter coupled to a delayed feedback. We identify the numerically optimal scheme at different system parameters. Our analysis provides a clear guideline on the selection of the generation scheme for graph-state-based quantum repeaters, and lays out the parameter requirements for future experimental realizations of different schemes.
Multi-Variable and Multi-Objective Gain-Scheduled Control Based on Youla-Kucera Parameterization: Application to Autonomous Vehicles
Authors: Atoui Hussam , sename Olivier , Milanes Vicente , Martinez-Molina John-Jairo
Published: February 2023

This paper presents a Youla-Kucera based interpolation between a set of
Linear Parameter-Varying (LPV) controllers, each one being a
gain-scheduled of Linear Time-Invariant (LTI) controllers designed
separately for different operating points. The gain-scheduling is
achieved based on Youla-Kucera (YK) parameterization. A generalized
LPV-YK control structure is designed to interpolate between various LPV
controllers. The closed-loop system is proved to guarantee the quadratic
stability for any continuous/discontinuous interpolating signals in
terms of a set of Linear Matrix Inequalities (LMIs). The proposed method
can help multi-variable and multi-objective systems to achieve high
performances at different operating conditions and different critical
situations regardless of the interpolation rate. A numerical example is
simulated to show the importance of the proposed method to achieve
different objectives for lateral control of autonomous vehicles. In
addition, the approach has been tested on a real Renault ZOE vehicle to
validate its real performance, and compare it with a standard polytopic
LPV controller.
IMMUNE RESPONSES IN TOXOPLASMOSIS AND MALARIA CO-INFECTIONS AMONG RESIDENTS OF RURAL COMMUNITIES IN SOUTHWESTERN NIGERIA
Authors: M Efenovwe, , ANUMUDU CHIAKA , Awobode H.O
Published: February 2023

Malaria and toxoplasmosis utilize similar known cellular and biochemical
pathways to modulate immune responses. Co-infections with malaria and
toxoplasmosis occur in malaria endemic regions but not much is known
about immune response modulation in these co-infections. Cytokine
profiles in response to malaria and toxoplasmosis co-infections were
determined in Akinyele, southwest Nigeria. Blood from 192 volunteers
were screened for Plasmodium falciparum,Toxoplasma gondii
antibodies (IgG and IgM) and cytokine (IL2, IL6, IL10 and IL12) levels.
PCV and epidemiological factors associated with toxoplasmosis and
malaria were also determined. Prevalence of co-infection was 20.4%,
Toxoplasma IgG and IgM was 27.5% and 8.98%,
respectively, while 2.6% had high levels of both Toxoplasma IgG
and IgM. Malaria prevalence was 72.9% and was highest in individuals
below 20 years of age, while toxoplasmosis was most prevalent in
51-60year olds. Toxoplasma sero-positivity, malaria prevalence
and Plasmodium intensity were significantly higher
(P<0.05) in females. High Toxoplasma IgG was associated
(P<0.05) with increased Plasmodium intensity and high
IgM with decreased intensity (P>0.05). IL-2 was higher
(59.02±0.19pg/ml) in malaria and Toxoplasma IgG co-infection.
IL-10 was significantly (P<0.05) elevated with IgM positivity
and malaria co-infection. IL-6 increased (P<0.05) with malaria
severity while IL-2 was lowest in severe malaria infections. Anaemia was
observed in 12.4% of participants, 13.6% of which were seropositive.
Active Toxoplasma gondii co-infection with malaria may suppress
malaria pathology while Plasmodium and chronic T.
gondii co-infection may lead to increased production of IL-2 which may
facilitate malaria parasite clearance. Malaria co-infection did not have
any effect on anaemia severity.
Formar ciudadanos y ciudadanos-líderes para nuestra sociedad: renovando la educación del carácter en las universidades
Authors:   University of Oxford, Brooks Edward , Villacís Jorge L. ,   Universidad de Navarra
Published: February 2023

Seventy-five years ago, the Universal Dec- laration of Human Rights promoted a vision of education “directed to the full development of the human personality and to the strength- ening of respect for human rights and fun- damental freedoms" (United Nations, 1948, 26.2). In 2015, the UN Sustainable Develop- ment Goals (SDGs) took this further, stating in SDG 4 that “the knowledge, skills, values and attitudes required by citizens to lead pro- ductive lives, make informed decisions and assume active roles locally and globally in facing and resolving global challenges can be acquired through education for sustainable development and global citizenship educa- tion” (United Nations Educational, Scien- tific and Cultural Organization [UNESCO], 2016, p. 14). What might the adoption of this educational mission involve for higher education? And what does it mean in a chal- lenging global context following the COVID pandemic and the Russian invasion of Ukraine? This paper argues that the current global tu- mult should catalyse reflection as to the pur- pose and content of higher education. It focus- es on the importance of education for “values and attitudes”, emphasized as an essential component of global citizenship and leader- ship education in the rubric of SDG 4. It pro- poses a return to the philosophical categories of “character” and “virtue”, arguing that the societal orientation of global universities and their aspiration “to educate the citizens and citizen-leaders for our society” (Harvard College, 2022) necessitates a renewal of theo- retically rigorous, pedagogically effective, and practically relevant character education.
El plural concepto del buen carácter
Authors:   Universidad Internacional de La Rioja, Ibáñez-Martín José Antonio
Published: February 2023

Support for character education has been gaining momentum in recent years, invariably in educational circles across the Anglosphere. This paper distinguishes between good charac- ter and buen carácter and highlights the distinc- tive features of the two meanings attributed to good character, particularly in Spanish. It un- dertakes a philological, philosophical and psy- cho-pedagogical analysis to this end. Moreover, it draws a distinction between temperament and good character and stresses the importance of developing a higher standard for good character, both for oneself and for those in whose hands educational responsibilities are placed. For this purpose, it considers the main human qualities at the heart of of good character based on a tras- cended reading of one of the most prominent representations of Spanish culture, The Ingenious Gentleman Don Quixote of La Mancha.
Los Colegios Mayores: el valor pedagógico de una institución centenaria
Authors:   Colegio Mayor Universitario Francisco de Vitoria, Ibáñez Ayuso María José
Published: February 2023

Every year, almost a third of Spanish uni- versity students move to another province to pursue higher education, and many housing op- tions are available to them (halls of residence, shared apartments, student residences, etc.). From a pedagogical standpoint, the question of the formative potential of each of these spaces arises. Since their birth more than six centuries ago, Colegios Mayores (a special model of Span- ish halls of residence) have contributed signif- icantly to the development of Spanish higher education and to promoting culture. However, there has been little research into these edu- cational institutions, meaning that their great cultural and pedagogical legacy is unknown. The aim of this study is to analyse the educa- tional value of the Colegios Mayores as forma- tive settings where the educational function of the university remains alive. With this purpose, from a hermeneutic-interpretative approach, these centres are analysed from the perspec- tive of both liberal and character education. This work concludes that Colegios Mayores are formative spaces at the forefront of education that offer their students a setting with a pro- found university experience, where the search for truth, the synthesis of knowledge, the en- counter with tradition, and the formation of critical thinking are combined with opportuni- ties for the cultivation of virtue, thus achieving an authentic comprehensive formation.
Assessment of thin bony structures using cone-beam computed tomography
Authors: Lennholm Camilla , Westerlund Anna , Lund Henrik
Published: February 2023

Objectives

To investigate the validity and reliability of marginal bone level measurements on cone-beam computed tomography (CBCT) images of thin bony structures using various reconstruction techniques, two image resolutions, and two viewing modes.

Materials and Methods

CBCT and histologic measurements of the buccal and lingual aspects of 16 anterior mandibular teeth from 6 human specimens were compared. Multiplanar (MPR) and three-dimensional (3D) reconstructions, standard and high resolutions, and gray scale and inverted gray scale viewing modes were assessed.

Results

Validity of radiologic and histologic comparisons were highest using the standard protocol, MPR, and the inverted gray scale viewing mode (mean difference = 0.02 mm) and lowest using a high-resolution protocol and 3D-rendered images (mean difference = 1.10 mm). Mean differences were significant (P < .05) at the lingual surfaces for both reconstructions, viewing modes (MPR windows), and resolutions.

Conclusions

Varying the reconstruction technique and viewing mode does not improve the observer's ability to visualize thin bony structures in the anterior mandibular region. The use of 3D-reconstructed images should be avoided when thin cortical borders are suspected. The small difference when using a high-resolution protocol is unjustified due to the higher radiation dose required. Previous studies have focused on technical parameters; the present study explores the next link in the imaging chain.
Effectiveness of Upadacitinib in Patients with Atopic Dermatitis including those with Inadequate Response to Dupilumab and/or Baricitinib: Results from the BioDay Registry
Authors: Boesjes Celeste M. , Van der Gang Liana F. , Zuithoff Nicolaas P.A. , Bakker Daphne S. , Spekhorst Lotte S. , Haeck Inge , Kamsteeg Marijke , De Graaf Marlies , De Bruin-Weller Marjolein S.
Published: February 2023

Clinical trials showed that upadacitinib, a selective Janus kinase-1 inhibitor, is effective for treatment of moderate-to-severe atopic dermatitis. However, daily practice studies are limited. This multicentre prospective study evaluated the effectiveness of 16 weeks of upadacitinib treatment for moderate-to-severe atopic dermatitis in adult patients, including those with previous inadequate response to dupilumab and/or baricitinib, in daily practice. A total of 47 patients from the Dutch BioDay registry treated with upadacitinib were included. Patients were evaluated at baseline, and after 4, 8 and 16 weeks of treatment. Effectiveness was assessed by clinician- and patient-reported outcome measurements. Safety was assessed by adverse events and laboratory assessments. Overall, the probabilities (95% confidence intervals) of achieving Eczema Area and Severity Index ≤ 7 and Numerical Rating Scale – pruritus ≤ 4 were 73.0% (53.7–86.3) and 69.4% (48.7–84.4), respectively. The effectiveness of upadacitinib was comparable in patients with inadequate response to dupilumab and/or baricitinib and in patients who were naïve for these treatments or who had stopped such treatments due to adverse events. Fourteen (29.8%) patients discontinued upadacitinib due to ineffectiveness, adverse events or both (8.5%, 14.9% and 6.4%, respectively). Most frequently reported adverse events were acneiform eruptions (n = 10, 21.3%), herpes simplex (n = 6, 12.8%), nausea and airway infections (both n = 4, 8.5%). In conclusion, upadacitinib is an effective treatment for patients with moderate-to-severe atopic dermatitis, including those with previous inadequate response to dupilumab and/or baricitinib treatment.
Development of Multiple Cherry Angiomas in a Child after COVID-19 Vaccination
Authors: Petersen Majken H. , Bjørn Marie
Published: February 2023

Abstract is missing (Short communication)
Modellversuch für die experimentelle Untersuchung des Verschleißverhaltens des Gleitschuh-Schrägscheibe Kontakts
Authors: Merkel Amos , Schlegel Felix , Schmitz Katharina
Published: February 2023

In axial piston pumps, hydrostatically partially balanced contacts are predominantly used. The use of these pumps in variable-speed configurations, such as in electro-hydrostatic axes, has proven to be very challenging in terms of robustness. Particularly affected here is the slipper-swashplate contact, via which the piston loads are supported. The wear processes and driving effects occurring here have not yet been sufficiently addressed in the current state of research. Within the scope of this publication, a model experiment is therefore to be presented which allows the targeted investigation of the wear behaviour of the slipper-swashplate contact under controlled and reproducible conditions. The objectives of the model experiment are, on the one hand, the empirical investigation of the interactions in variable-speed operation and, on the other hand, the validation of simulative considerations.
METODE NHT DAPAT MENINGKATKAN PRESTASI BELAJAR MATERI LEMBAGA DALAM SUSUNAN PEMERINTAHAN DESA DAN KECAMATAN KELAS IV SDN III LAE LONGKIP
Authors: Suparjo Suparjo
Published: February 2023

Abstrak: Metode NHT dapat Meningkatkan Prestasi Belajar Materi Lembaga dalam Susunan Pemerintahan Desa dan Kecamatan Kelas IVSDN III Lae Longkip. Penelitian ini bertujuan untuk meningkatkan prestasi belajar siswa kelas IV SDN SP III Lae Longkip. Subjek penelitian ini siswa kelas IV SDN SP III Lae Longkip dengan jumlah siswa 12 siswa, Data yang dihimpun berupa, aktivitas siswa, dan guru serta hasil tes. Peningkatan yang diperlihatkan siswa bukan hanya harus dalam proses belajar, tetapi juga ada hasil yang diperoleh siswa baik secara perseorangan maupun perkelompok. Jika dibandingkan antara nilai tes awal, nilai tindakan siklus I dan nilai akhir siklus II tampak peningkatan dari 50 % (cukup) menjadi 83,33 % (sangat baik).Kata Kunci: Pembelajaran, Numbered Head Together, Prestasi Belajar Siswa
PENERAPAN LAYANAN MEDIASI UNTUK MENGURANGI PERKELAHIAN ANTAR SISWA SMP NEGERI 5 PERCUT SEI TUAN
Authors: Hasni Erna
Published: February 2023

Abstract: Application of Mediation Services to Reduce Fighting Between Students of SMP Negeri 5 Percut Sei Tuan. The purpose of this study is to reduce fights between students through the application of mediation services and to find out the enhancement of the skills of the BK Guidance teacher conducting mediation services. The study was conducted at SMP Negeri 5 Percut Sei Tuan starting from early February 2017 to June 2017 with two cycles of action. The subjects in this study were 10 students from SMP Negeri 5 Percut Sei Tuan who were involved in a fight in the school environment. The results showed that the application of mediation services to overcome fights in SMP Negeri 5 Percut Sei Tuan can reduce the level of fighting among students.Keywords: service, mediation, fightingAbstrak: Penerapan Layanan Mediasi untuk Mengurangi Perkelahian Antar Siswa SMP Negeri 5 Percut Sei  Tuan. Tujuan penelitian ini adalah untuk mengurangi perkelahian antar siswa melalui penerapan layanan mediasi dan untuk mengetahui peningkatan keterampilan Guru BK melakukan layanan mediasi. Penelitian dilakukan di SMP Negeri 5 Percut Sei Tuan mulai dari awal Februari 2017 sampai Juni 2017  dengan dua siklus tindakan. Subjek dalam penelitian ini adalah siswa-siswi SMP Negeri 5 Percut Sei Tuan berjumlah 10 orang yang terlibat dalam perkelahian di lingkungan sekolah. Hasil penelitian menunjukkan bahwa penerapan layanan mediasi untuk mengatasi perkelahian di SMP Negeri 5 Percut Sei Tuan dapat mengurangi tingkat perkelahian antar siswa.Kata kunci: layanan, mediasi, perkelahian
MENINGKATKAN HASIL BELAJAR SISWA PADA MATA PELAJARAN IPA DENGAN METODE DEMONTRASI DI KELAS VII-1 SMPN 1 PATUMBAK
Authors: Nadapdap Erika
Published: February 2023

Abstract: Improving Student Learning Outcomes in Science Subjects Using Demonstration Methods in Class VII-1 SMPN 1 Patumbak. The purpose of this study was to determine the increase in students' science learning outcomes through the application of the Demonstration method in science subjects for Class VII-1 students of SMPN 1 Patumbak T.A 2018/2019. Student activities in the learning process of demonstrations each cycle have increased. This has a positive impact on student achievement, which can be shown by increasing the average value of students in each cycle. This can be seen from the increasingly solid understanding of students towards the material delivered by the teacher (mastery learning increases from cycles I, II, and III), namely respectively 67.57%, 78.38%, and 89.19%. In cycle III students' classical learning completeness has been achieved.Keywords: Learning Outcomes, Demonstration Method, Science LearningAbstrak: Meningkatkan Hasil Belajar Siswa Pada Mata  Pelajaran IPA Dengan Metode Demonstrasi Di Kelas VII-1 SMPN 1 Patumbak. Tujuan penelitian ini adalah untuk mengetahui peningkatan hasil belajar IPA siswa melalui penerapan metode Demonstrasi pada mata pelajaran IPA siswa Kelas VII-1 SMPN 1 Patumbak T.A 2018/2019. Aktivitas siswa dalam proses pembelajaran demonstrasi setiap siklus mengalami peningkatan. Hal ini berdampak positif terhadap prestasi belajar siswa yaitu dapat ditunjukkan dengan meningkatnya nilai rata-rata siswa pada setiap siklus. Hal ini dapat dilihat dari semakin mantapnya pemahaman siswa terhadap materi yang disampaikan guru (ketuntasan belajar meningkat dari siklus I, II, dan III) yaitu masing-masing 67,57%, 78,38%, dan 89,19%. Pada siklus III ketuntasan belajar siswa secara klasikal telah tercapai.Kata kunci: Hasil belajar, Metode Demonstrasi, Pembelajaran IPA