bluuebunny/crossref_metadata_2025 huggingface dataset:
Effect of accelerated cooling after cross-helical rolling on formation of structure and low-temperature fracture toughness of low-carbon steel
Authors: Gordienko A. I. , Vlasov I. V. , Pochivalov Yu. I.
Published: November 2023

The effect of accelerated cooling after cross-helical rolling of X70 low-carbon steel on the formation of structures and mechanical properties under static tension and impact bending was investigated. The use of interrupted accelerated cooling of steel after cross-helical rolling with exposure at 530 °C (mode I) and continuous accelerated cooling (mode II) leads to the formation of different types and ratios of structures in steel. After rolling according to mode I, the structure is characterized by the presence of ferrite, troostite, granular bainite, and fine Fe3C carbides. After rolling according to mode II, the structure is characterized by the formation of lath bainite and large sections of the martensitic-austenitic (MA) component up to 1 – 2 µm in size. It is shown that a decrease in the fineness of ferrite grains in steel after cross-helical rolling in modes I and II from 12 to 4.6 – 4.3 μm, the formation of a bainitic phase, and hardening of the matrix with carbides led to an increase in the yield strength of steel up to 440 and 490 MPa and tensile strength up to 760 and 880 MPa. Carrying out helical rolling according to mode I makes it possible to significantly increase the low-temperature fracture toughness of steel (KCV–70 °С = 160 J/cm2) compared to the hot-rolled state (KCV–70 °С = 11 J/cm2) and reduce the cold brittleness of steel to the temperatures below –50 °C. The use of continuous accelerated cooling (mode II) does not allow increasing the cold resistance of steel due to the formation of the lath bainite structure and large areas of the MA component.
Construction of Territory Through Cyberspace: A Latin American View of Young People's Perception of Virtual Space
Authors: Hidalgo Luis Bernal , Mican Edgar Olmedo Cruz , Ed Fernando Augusto Poveda Aguja , Guerrero Lugo Manuel Barbosa , Guzman Marcia Andrea Yucuma , Ed Pedro Antonio Vela González
Published: November 2023

This article presents a balance about the chapter guidelines for teaching construction of the territory concept in schools today, which is part of the doctoral thesis "La construcción del territorio a través del ciberespacio: una mirada latinoamericana de la percepción de los jóvenes frente al espacio virtual. Presented at University of Valencia, Spain. This unit was focused on the construction of guidelines for learning the territory concept in geography, it is set from a comparative analysis between Spain, Colombia and England, in order to reflect the contributions of the Latin American, European and Anglo-Saxon countries, in line with the reconstitution of geographic knowledge at a global level to expand new approaches to the concept. This is in contrast to the policies in charge of regulating education in these countries. In this way, it is intended to make analytical and conceptual contributions of the territory from teachers' point of view in relation to the discussion of the territorial approach given by these institutional spaces to expand and develop a conceptual framework that contributes to generating significant transformations in the daily activity of educators. proposing a shift in the geography learning, which allows re-meaning the concept of territory in accordance with innovations in knowledge.
Anti-inflammatory and Antioxidant Effects of Grapefruit Juice on Ulcerative Colitis induced by Acetic Acid in Rats
Authors: Mohamed Asmaa Mahmoud A. , Shalaby Mostafa A. , Ismail Neveen S.
Published: November 2023

Grapefruit is commonly consumed around the world due to its nutritional and medicinal properties. Ulcerative colitis (UC) accounts for an inflammatory bowel disease (IBD) accompanied by irritation, recurrent inflammation, and ulceration of the colon's mucosa. Our objective was to assess the antiinflammatory and antioxidant impacts of grapefruit juice (GFJ) in rat with UC induced by acetic acid (AA). There were five groups made up of 35 mature male rats. Group 2 served as a positive control with UC, whereas group 1 was preserved as a negative control. For 8 weeks, groups 3, 4, and 5 received UC while also given 2.5, 5 or 10% of GFJ orally. Feed efficiency ratio (FER), body weight growth (BWG), and feed intake (FI) were computed. From rat eye orbital plexuses blood samples were taken to separate the serum after centrifugation.  The aspartate aminotransferase (AST) and alanine aminotransferase (ALT) activity were assessed utilizing serum samples. The antioxidant enzymes catalase (CAT), glutathione peroxidase (GPx), and superoxide dismutase (SOD) in serum were quantified. Serum inflammatory cytokines as tumor necrosis factor alpha (TNFα), interleukin 1 β (IL1 β), IL6 and IL8, as well as triglycerides (TG) and total cholesterol (TC) were measured. In liver homogenate, glutathione (GSH) and malondialdehyde (MDA) were determined. Additionally, histopathology of the colon was accomplished. Our findings specified that GFJ at 10% significantly decreased FI, BWG and FER, cytokines TNFα, IL1 β, IL6 and IL8 and TC and TG. Relative to the positive controls, the rats treated with GFJ exhibited elevated serum concentrations of SOD, GPx, and CAT enzymes. Liver GSH was elevated and MDA was reduced. Histopathological examination of the colon showed that GFJ at 10% reduced ulcerative colitis. Because grapefruit juice has strong anti-inflammatory and antioxidant characteristics and reduces oxidative stress and inflammation in rats, grapefruit juice, at a concentration of 10%, likely protects against ulcerative colitis. Patients with ulcerative colitis may find it helpful to consume grapefruit juice as a beverage.
Emergency intestinal stomas incidence and early complications
Authors: Sah Bikash K. , A. Nashed George , Ahmed Ahmed N. , Raslan Mohamed M.
Published: November 2023

Background: An intestinal stoma is a frequently performed procedure with a high percentage of complications. Even though creating an intestinal stoma is a procedure that can save lives while treating various gastrointestinal conditions, its accompanying morbidity and mortality have been the topic of many studies. This study was carried out in order to better understand a variety of complications in various types of intestinal stomas.
Methods: A total of 60 patients with intestinal stoma construction in the general surgery emergency department at Kasr Al-Ainy emergency hospital Cairo, Egypt as an emergency procedure from December 2019 to May 2020 were included in this prospective cohort analysis. The inclusion criteria were all emergency cases undergoing intestinal stomas for treatment of either traumatic bowel injuries or acute abdominal surgical emergencies.
Results: With a mean age of 45.18 years, 60 patients in all were evaluated. Males were 65% and females were 35%. End ileostomy with mucous fistula (33.3%) and loop transverse colostomy (18.30%) were the two stomas that were constructed most frequently. Intestinal obstruction (41.7%) was the most often reported indication of stoma formation. Complications of the peristomal skin made up the majority of cases (61.90%).
Conclusions: This work significantly advances our understanding of stoma problems and their prevention to some extent through pre-operative soma site marking, good surgical technique, an experienced surgeon, a stoma therapy nurse, and patient education to enhance the care and quality of life for those who have stomas.
Qualidade de vida em pacientes portadores de doenças reumáticas
Authors: Rodrigues Andreza Pinheiro , Rodrigues Wállane Pinheiro , Nogueira Tiago Bezerra de Sá de Sousa , Souza Waerson José de , Sousa Milena Nunes Alves de
Published: November 2023

Buscou-se avaliar a qualidade de vida dos pacientes portadores de doenças reumáticas, bem como os aspectos que podem proporcionar melhorias na vida destes pacientes. Este estudo foi realizado por meio de uma revisão integrativa da literatura, com enfoque em pacientes reumáticos. Para busca e obtenção dos artigos, foi escolhida a base de dados Scientific Elecronic Library Online (ScIELO), a National Library of Medicine (MEDLINE) e a Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS). Foram utilizados os descritores ‘’qualidade de vida’’ e ‘’doenças reumáticas’’, unidos a partir do operador boleano ‘’and’’. Os critérios de inclusão foram artigos publicados em revistas científicas, no período de 2016 a 2018. Foram selecionados 80 artigos e após a leitura integral, restaram 32, os quais foram subdivididos em quatro categorias. Encontrou-se que a atividade física, atividade da doença, saúde mental, tratamento medicamentoso e abordagem multidisciplinar apresentam grande influência na qualidade de vida dos pacientes. Evidenciou-se a necessidade de uma abordagem multidisciplinar em todos os pacientes portadores de doenças reumáticas, a fim de proporcionar melhorias em sua saúde física e mental.
Influência do café na Doença de Parkinson
Authors: Carvalho Laura Oliveira Rolim de , Valério Damiana Gerleide Brito , Nóbrega Hellen Maria Gomes da , Dantas Isabel Cristina Medeiros , Leite Natanyelle da Silva Braga , Sousa Milena Nunes Alves de
Published: November 2023

Objetivou-se analisar a influência do consumo do café sobre a Doença de Parkinson (DP) e correlacionar os possíveis efeitos dessa substância com o tratamento da DP. Trata-se de uma Revisão Integrativa da Literatura a partir da busca do tema na literatura científica com os descritores controlados em ciência da saúde em inglês coffee OR caffeine AND "Parkinson Disease” As bases de dados eleitas foram Biblioteca Virtual em Saúde, Medical Publisher, totalizando 606 artigos. Os critérios de exclusão com o uso dos seguintes filtros: espécie humana, artigos completos, data de publicação (últimos cinco anos), palavras chave do título, abordagem da questão norteadora, delimitaram 24 artigos. Dentre os resultados, 74,19% relataram o efeito protetor do café, já 4,16% dos estudos apontaram efeitos deletérios de um componente do café - a cafeína, como dificuldade cognitiva, aumento da discinesia e até mesmo uma piora na progressão de DP, caso tenha associação com a substância creatina, por exemplo. Contudo, a maioria dos estudos defende a neuroproteção propiciada pelo café. De acordo com os artigos analisados, a ingestão de café apresenta mais reações benéficas do que prejuízos e demonstra uma melhoria sintomática da DP. A cafeína foi associada a diminuição de tremores concatenados ao comprometimento motor e não motor ao longo da evolução da patologia. Apesar, de notoriamente positiva na melhora parkinsoniana, ainda são necessários mais evidências clínicas para a inserção da cafeína num possível tratamento coadjuvante de DP.
Produção e acesso as redes sociais científicas por doutores docentes de Instituição de Ensino Superior
Authors: Sousa Milena Nunes Alves de , Almeida Flávio Franklin Ferreira , Melo Alana Candeia de , Almeida Elzenir Pereira de Oliveira
Published: November 2023

Objetivou-se realizar um diagnóstico situacional da produção e acesso as redes sociais científicas por doutores docentes de instituição de ensino superior (IES) do sertão da Paraíba. Especificamente, averiguar a formação dos doutores; identificar as áreas de doutoramento; verificar a atualidade na produção científica; e investigar o acesso às mídias sociais científicas pelo grupo. Foi realizada pesquisa descritiva, documental e efetivado o método sistemático bibliométrico. O estudo efetivou-se a partir de dados de docentes doutores de IES paraibana. Adicionalmente, foi feita a pesquisa na Plataforma Lattes, entre os meses de maio e junho de 2019. Os dados foram analisados a partir de estatística descritiva simples. Os resultados indicaram que os doutores docentes presentam baixa produção científica, o que invalida o processo de doutoramento destes sujeitos e desqualifica o processo de ensino, pesquisa e extensão, pilares do ensino superior. Também, têm pouco acesso às mídias sociais científicas. Assim sendo, é fundamental ampliar a rede de relacionamentos e a elaboração de um plano estratégico de desenvolvimento científico para o grupo.
Metodologia ativa na extensão universitária: um relato de experiência
Authors: Lima Irismar Batista de , Mascêna Maria do Socorro , Sousa Milena Nunes Alves de
Published: November 2023

Novas estratégias de estudos vêm incentivando mudanças no ensino, essas práticas têm implicado de forma positiva na aprendizagem. Esse trabalho emprega como recurso o uso da metodologia ativa, objetivando apresentar a experiência no ensino e aprendizagem numa extensão universitária com método de observação e relato de experiência. Participaram oito discentes e um docente, durante quatro meses, onde existiram atividades de observação e práticas numa Comunidade Remanescente de Quilombo, município de Cacimbas, Paraíba, Brasil. A metodologia foi desenvolvida em oito encontros, sequencial e complementar; através dos recursos tecnológicos com um grupo de whattsap e de e-mail para socialização e trocas de informações, durante o primeiro mês os discentes realizaram observação, em seguida escuta na comunidade por dois meses, e as atividades práticas na comunidade no último mês. Nesse percurso o foco foi aprender e ensinar, contribuir e compartilhar experiências. Finalmente dizer que conhecer o uso da metodologia ativa na extensão universitária conduz para uma reflexão construtiva sobre o ensino, a didática, a formação e atuação do ensinante.
Ruderal vegetation (Ruderalophyton) of transformed habitats of the Rostov-on-Don urban ecosystem, Russia
Authors: Litvinskaya S. A. , Gorbov S. N. , Dzigunova Yu. V.
Published: November 2023

Aim. To investigate the features of the abiotic (soils) and biotic (flora and vegetation) components of ruderal communities (Ruderalophyton) of the urban ecosystem in the conditions of the Rostov agglomeration.Material and Methods. The morphoecological analysis of the flora (144 species of vascular plants) was shown. Data were obtained of the characteristic growth features of roadside communities of the Southern Federal University Botanical Garden (floristic diversity of 53 species) and of ruderal communities of new residential building plots in the peripheral part of the city and abandoned houses in the central part of the city.Results. Abiotic conditions for the habitats of ruderal plants are no longer natural because the local Chernozem root‐inhabited and humusaccumulative surface horizons have been almost completely stripped away. At the same time, cenotically the communities are multicomponent and floristically saturated with high projective coverage. During the process of anthropogenic vegetation evolution, a new type of cenosis has formed, which is adapted in ecological succession processes to all components of the urban ecosystem.Conclusion. The ruderal vegetation of the Rostov agglomeration is particularly resistant. It develops urban horizons, which are characterized by a high proportion of anthropogenic inclusions; household, and industrial waste, which is often contaminated with organic and inorganic pollutants. Plant communities developing on such substrates are multicomponent, floristically saturated and have formed a high degree of projective cover.
Experimental study of the structure of variability of natural populations of Origanum vulgare L. from mountainous Dagestan, Russia
Authors: Musaev A. M. , Radzhabov G. K. , Aliyev A. M. , Islamova F. I.
Published: November 2023

Aim. To identify plasticity and stability and to evaluate interpopulation differentiation in terms of accumulation of secondary metabolites in an ecological and geographical experiment with two model populations of Origanum vulgare L., belonging to different subspecies and vicarious along the altitudinal gradient.Material and Methods. Ecological and geographical experiment with transplanted plants of Origanum vulgare L. at two experimental bases, at altitudes of 1100 and 1730 m and simulating the conditions of the mountain‐valley and upper mountain belts. The total content of antioxidants was determined by the electrochemical method. The essential oil was obtained by hydrodistillation on a Clevenger apparatus. The component composition of the oil was established on a gas chromatograph with a mass spectrometric detector. Components were identified using mass spectra libraries.Results. We studied the structure of variability in the yield and component composition of essential oil, as well as the total antioxidant activity in two populations of Origanum vulgare L. belonging to different subspecies. Regularities have been revealed that make it possible to attribute the studied populations to foothill and highland ecotypes.Conclusions. The yield of essential oil and the content of total antioxidants are clearly correlated with the conditions in the experimental plots and are not associated with microevolutionary processes under the control of abiotic factors of the altitudinal gradient.
The study of the course of the infectious process in lungs of cats during experimental infection with SARS-CoV-2
Authors: Filippova A. Yu. , Fedotova M. S. , Kononova Yu. V. , Shestopalova L. V. , Gulyaeva M. A.
Published: November 2023

Aim. To study and characterise the features of the course of coronavirus infection in a domestic cat model, as well as to assess the danger of SARSCoV-2 isolated in Russia for these animals based on the data obtained, with the possibility of extrapolating to wild felines.Material and Methods. For the study, model animals – Felis silvestris catus – were divided into 3 groups. The viral strain of SARS-Cov-2/human/RUS/Nsk-FRCFTM-1/2020 was cultivated on Vero E6 cell culture and then administered intranasally in a volume of 200 μl, 105TCID50/ml, to animals from the first and second groups. Model animals from the first group were euthanized and lung fragments were taken on 6–day post infection (d.p.i.), animals from the second group – on 14 d.p.i. The third group – the control group, was injected with saline in an equivalent volume. Histological sections colored with hematoxylin and eosin were investigated for pathomorphological changes in lung tissue using light microscopy.Results. According to the obtained results the pathomorphological picture in the lungs of experimental animals indicates the course of interstitial pneumonia for both 6 and 14 d.p.i. In addition, it has been determined that by 14 d.p.i. the growth of fibrous tissue in the lungs begins to be visualised, indicating the beginning of light regenerative processes.Conclusion. The study showed that cats are susceptible to the SARS-CoV-2 virus, and these model animals are characterized by the emergence of clinical manifestations and morphological patterns in the lungs, which correspond to interstitial pneumonia.
Analysis of Dynamics and Restructuring of PT Pertamina (Persero)
Authors: Pangestu Ririh Aji
Published: November 2023

Since its inception, PT Pertamina (Persero) has experienced many organizational dynamics or changes. ranging from changes in name and status, refining the vision, to restructuring the company. Through a qualitative approach by applying the literature review method, it is interesting to analyze, describe, and discuss further the dynamics or changes that occur in PT Pertamina (Persero), namely restructuring in 2018 to 2021 through the formation of a holding company, as well as the implications in relation to company performance. As a result, it appears that the holding-sub-holding framework as a form of restructuring is an appropriate choice taken by the Indonesian government (as a shareholder) in connection with a series of positive results (in the form of profit optimization and operational cost efficiency) that are quite significant. Because of restructuring, the organizational or operational structure of PT Pertamina (Persero), which was originally so fat and large, resulting in a slow decision-making process, has become lean. This has good implications for the company, which has become faster, more agile and concise in the decision-making process. In addition, there is clarity of authority between PT Pertamina (Persero) as a holding company and its sub-holdings.
Urban Health for the Development of Healthy Cities in Indonesia
Authors: Christian Deyo Alfa , Bachtiar Adang , Candi Cicilya
Published: November 2023

Sustainable urban development, healthy cities and rapid urban growth have become a major focus in Indonesia. This research aims to identify the key factors needed to achieve optimal Urban Health in Indonesia. Currently, DKI Jakarta Province is the largest metropolitan city in Indonesia, but in 2022 DKI Jakarta will be ranked 238th in the world and 48th in Asia regarding the Quality of Life Index. A symbol of success and progress in the country of Indonesia, there are 98 cities spread across all provinces, but only 8 cities are included in the metropolitan category. This research uses the PRISMA extension for Scoping Review (PRISMA-ScR) guidelines, 93 articles published between 2000 and 2022 meet the inclusion criteria that look at Urban Health for city development. In an effort to build a healthy city, Urban Health needs to be implemented using several key factors that encourage good urban health. The policy approach in Indonesia must be to improve the quality and accessibility of health services which are important factors in the effectiveness of urban health services, so as to achieve good urban health. well in Indonesia requires a holistic approach that includes green energy, a clean environment, high levels of physical activity and good stress management, adequate health services, good nutrition and equitable health.
Multi-indicator optimization of riveting joint forming quality of aluminum alloy sheets based on response surface test
Authors: Liu Shi , Zhao Yong Qiang , Wang Da Hai , Mei Miao Yuan , Huang Tao
Published: November 2023

In this paper, the effects of the interaction between punch diameter, die depth and punch speed on the quality of riveted joints are investigated using the BBD response surface test method. The results show that the mold depth has the greatest influence on the key dimensional parameters of riveted joints, followed by the punching speed, and then the punch diameter, while the punch diameter and the mold depth are the two factors with the most obvious interaction. The optimum riveted joint process parameters determined are punch diameter of 5.24 mm, die depth of 1.44 mm, and stamping speed of 5.00 mm/s. The corresponding relative errors predicted by numerical simulation and response surface optimization objective are 5.96 % for neck thickness, 3.29 % for interlocking value, and 1.37 % for bottom thickness; and the relative errors predicted by experimental results and optimization objective are 13.42 % for neck thickness, 13.42 % for interlocking value, and 1.37 % for bottom thickness. 13.42 %, interlock value is 4.23 %, and bottom thickness is 2.23 %, the model accuracy is high, and the optimization method of response surface test can effectively improve the quality of riveted joints. Through numerical simulation, the metal flow law and stress distribution during the riveting and forming process of aluminum alloy plate were analyzed, and the strength test of riveted joint was carried out, and the maximum destructive shear load of the joint was 1.8 KN, and the strength of the joint was improved, which verified the validity of the response surface optimization method.
A comprehensive review of mechanical fault diagnosis methods based on convolutional neural network
Authors: Hou Junjian , Lu Xikang , Zhong Yudong , He Wenbin , Zhao Dengfeng , Zhou Fang
Published: November 2023

Mechanical fault diagnosis can prevent the deterioration of mechanical equipment failures and is important for the stable operation of mechanical equipment. Firstly, this paper reviews three basic methods of fault diagnosis and common methods of data-driven fault diagnosis, focusing on the characteristics and advantages of deep learning and convolutional neural networks. Then, the basic structure and working principle of CNN (Convolutional Neural Networks) and some basic methods to achieve better training results are introduced. In the next place, from data processing, data fusion, sample set construction, and so on, it is reviewed that the method of fault diagnosis based on CNN and their application scenarios and advantages and disadvantages; for another, the related knowledge and concepts of transfer learning are introduced, and some current application scenarios and advantages and disadvantages of mechanical fault diagnosis techniques combining migration learning and convolutional neural networks are reviewed. Finally, the current difficulties and challenges of convolutional neural networks are discussed, and the research directions have been prospected for CNN applied to the field of fault diagnosis. Although there is quite some similar literature reviewed, this review aims to introduce the basic methods of fault diagnosis, which draw forth the basic applications of the fault diagnosis of data-driven, CNN in the domain of fault diagnosis, and the application scenarios and advantages and disadvantages of combining TL (Transfer Learning) and CNN in fault diagnosis, as well as some problems and prospects. It helps researchers to have a basic understanding of this.
How to use Ethics. Review of Applied Ethics. An Introduction, by Robin Attfield
Authors: Waleszczyński Andrzej
Published: November 2023

Studia Ecologiae et Bioethicae does not provide abstracts for book reviews.
Intelligent static synchronous compensator with super-capacitor for enhancement of power network security
Authors: Vaidya Prajakta , Chandrakar Vinod
Published: November 2023

Power network security becomes an important issue for power system economics. A proportional integral-based static synchronous compensator in flexible AC transmission systems is generally used to enhance power network security. But, it takes more time to make the network stable and secure. A PI-controlled STATCOM with a super-capacitor as an electrical storage device and transient performance improver helps the network become stable and secure. As the PI controller depends on mathematical modeling, it may respond slowly, affecting the stability and security of the network. A fuzzy logic controller, as an intelligent controller with logical rules, can overcome the slow response problem of PI controllers. Hence, to enhance power network security, an intelligent static synchronous compensator in coordination with a super-capacitor is suggested here. A multimachine network is modeled in a MATLAB environment with severe faults near the generator, making it unstable and unsecure. The validation of the proposed combination is observed by comparing the performance of the network without STACOM, with conventional PI STATCOM, with intelligent STATCOM, and with intelligent STATCOM coordinated with a super-capacitor.
The relationship between serum TIM-3 and TIM-3 gene expression
in a sample of Iraqi patients with multiple sclerosis
Authors: Shaker Hammood Fadel , asim Mohammed Bushra J
Published: November 2023

Multiple sclerosis (MS) is an autoimmune disease of the central
nervous system (CNS) caused by auto-reactive T cells against
myelin antigens. T-cell immunoglobulin mucin -3 (TIM-3) is a
negative regulator glycoprotein expressed by a range of immune
cells. A defect in TIM-3 regulation has been shown in multiple
sclerosis patients. This study was planned to investigate the
correlation between serum TIM-3 and TIM-3 gene expression in
a sample of Multiple Sclerosis Iraqi patients. Three ml of blood
samples were collected from fifty Iraqi patients who have
Multiple Sclerosis (men and women) with ages ranging between
20-57 years, and 50 healthy volunteers as a control group;
0.25ml of blood was put in Trizol tube for RNA extraction,
subsequently to estimate TIM-3 gene expression by one step
RT-qPCR, and 2.75 ml of blood placed into gel tube for
determination TIM-3 serum level by enzyme-linked
immunosorbent assay (ELISA), the Statistical analysis was done
by using program of Statistical Analysis System (SAS). There
was a significant increase (P ≤ 0.05) in TIM-3 gene expression
for patients (5.30-fold) when compared with control (7.86-fold).
Moreover, the result demonstrated a high significant elevated (P
≤ 0.01) in TIM-3 serum level of patients (0.398 pg/ml) as
compared to control (3.17 pg/ml. Furthermore, the findings
showed a strong positive association between TIM-3 serum
level and TIM-3 mRNA expression with significant differences.
The current study concluded that the TIM-3 gene expression and
TIM-3 serum level were high in MS patients, and there was a
direct positive relationship between TIM-3 gene expression and
TIM-3 serum level.
Keywords: MS, TIM-3, RT-qPCR.,ELISA
Effect of adding different levels of Artichoke (Cynara scolymus)
aqueous extract to Tris extender on the Motility, Viability and some
characteristics of rams semen stored at 5 °C
Authors: Khirija AL-Badri Zina Rashid , Hussein Banana Husam Jasim
Published: November 2023

This study was conducted to show the effect of the aqueous extract of the leaves
of Artichoke ( Cynara scolymus L.) on Tris extender and its effect on the semen
traits of Awassi rams after preservation at a cooling of 5° C for different periods
(0, 24, 48 and 72 hours). This study was conducted in the animal field and laboratories of the Department of Animal Production, College of Agricultural Engineering Sciences, University of Baghdad in Jadiriyah, from November 15, 2021 to
April 25, 2022. Three local Awassi rams were used in this experiment. Their ages
ranged from 2.5-3.0 years. The semen was collected from them by artificial vagina
by one ejaculation/ram/week for 8 weeks. The semen of rams has been mixed in
order to eliminate individual differences. The following tests were conducted to
evaluate the semen characteristics for each motility, the percentage of viability
sperm, total abnormalities, the integrity of the plasma membrane, and the acrosome's integrity. The current study showed that adding an aqueous extract from the
leaves of the artichoke plant (Cynara scolymus L.) improved most of the studied
traits when stored in preservation. The results indicated a highly significant
(P<0.01) for the treatments T1, T2 and T4, which amounted to (87.00 ± 1.86, 85.50
± 2.02 and 86.87 ± 0.78%) compared to the control group (C), which amounted to
(77.25 ± 2.11%), While the previous treatments did not differ significantly with
treatment T3, which amounted to (81.87 ± 2.94%) in the percentage of live sperm
during the 0 hour preservation period. At the same time, the results indicated no
significant differences between treatments T1, T2, T3 and T4 compared to the control treatment and for all periods (0, 24, 48 and 72 hours) in the individual motility
of the sperm. As for measuring the biochemical traits of seminal plasma, The results of AST and ALT enzymes indicated that there was no significant increase
between treatments during one period, while an arithmetic superiority occurred after 72 hours of preservation for treatments T1, T2, T3 and T4 compared with the 0
hour preservation period. It is concluded from the current study that adding an
aqueous extract of (Cynara Scolymus) artichoke leaves to Tris extender improved
the semen quality of Awassi rams after preservation.
Keywords: Ram; Semen; Antioxidants; Cooling; Artichoke; Cynara Scolymus.
Evaluation of some Herbal Agents in the treatment of Diabetes in Comparison to Insulin
Authors: F. H. Al-Musawi Jawad
Published: November 2023

We conducted an experimental investigation in which hyperglycemia was created in rats using Alloxan; we then employed an herbal drug that could reverse the hypoglycemic effects of insulin, which is to say, we used Alloxan to induce hyperglycemia in the rats. Research conducted on 24 Black rats over 28 days (split into four groups of six rats each on days 1, 7, 14, and 28) shows that ALLOXAN can induce hyperglycemia with statistical significance (P0.0001). HERBAL DRUGS (Momordica Charantia L) have effectively reduced hyperglycemia brought on by Alloxan, with statistically significant results (P0.0001) but not as strong as those produced by insulin. Momordica Charantia L for its insulin-like effects on blood sugar levels in the context of hyperglycemia produced by Alloxan. Through the use of "Black rats," we were able to successfully visualize a model for inducing hyperglycemia via intraperitoneal injection of ALLOXAN. The effectiveness of Momordica charantia L in bringing down hyperglycemia was then compared to that of insulin. Comparing Momordica charantia L to insulin for the treatment of type 1 diabetes in rats, the following results were found: - On days 7, 14, 21, and 28, with a total of 6 animals (Black rats) in each group, the mean S.D. of the hypoglycemic effect of Momordica charantia L was (148.42 +/-3.65), (127.66 +/- 2.520), (95.78 +/-1.18), and (86.54 +/3.55). To put it another way, the herbal remedy effectively lowers blood sugar levels in those who suffer from hyperglycemia. The present findings highlight that Momordica charantia L effectively treats type 1 diabetes mellitus in rats and has the same effect on blood glucose levels as pharmaceutical insulin. Keywords: Alloxan, Hypoglycemia, Insulin, Momordica charantia L, Hyperglycemia.
The relationship between meal timing and depression in children and adolescents: a cross-sectional study in China. (Preprint)
Authors: Li Huilun , Zhang Erliang , Liu Yujie , Ge Xin , Chen Minzhi , Zhang Jie , Cui Shuheng , Takahashi Masaki , Lu Zhaohui , Xiang Mi
Published: November 2023

BACKGROUND

Meal timing, the schedule of meal consumption, has been related to several metabolic disorders. However, the effect of meal timing on mental health is scares, particularly in children and adolescents who are in a critical period of physical and psychological development.

OBJECTIVE

This research examined the relationship between meal timing and depression in children and adolescents.

METHODS

Children and adolescents from grades one to nine were recruited from 14 districts in Shanghai, China from January 3rd to January 21st. A survey was distributed to the students and their parents to collect the corresponding information. Depression was measured by the Children's Depression Inventory-short form (CDI-S). Meal timing, including breakfast frequency, food intake before sleep, and daily eating window, were assessed by the survey. A total of 6874 participants were included in the analysis. The logistic regression model was used to compute the odds ratios (OR) and 95% confidence intervals.

RESULTS

Participants who skip breakfast were associated with a 2.73 time higher risk of depression (OR=2.73, 95%CI: 2.27-3.29, P< 0.001). Depression was 1.28 times higher in participants who ate before bed than participants who never ate before bed (OR= 1.28, 95%CI: 1.08-1.51, P< 0.001). The risk of depression is 1.37 times higher if the eating time window was shorter than 10 hours (OR= 1.37, 95%CI: 1.08-1.73, P=0.009) and 1.23 times higher if the eating time window was longer than 12 hours (OR= 1.23, 95%CI: 1.01-1.50, P=0.042). The lowest risk of depression was observed at 11.5 hours.

CONCLUSIONS

depression was observed at 11.5 hours.
Conclusion
Breakfast skipping and eating before bed increases the risk of depression. The optimal daily eating window to lower the risk of depression is 11.5 hours in children and adolescents.
Effectiveness of a Nursing Educational Intervention in Adults to Promote Control Behaviors Against Dengue: Protocol for a Randomized Controlled Trial (Preprint)
Authors: Llorente Pérez Yolima Judith , Rodríguez-Acelas Alba Luz , Mattiello Rita , Cañon-Montañez Wilson
Published: November 2023

BACKGROUND

The increase in dengue cases can be attributed to social, demographic, environmental changes, or community-driven factors. In this regard, different strategies have been established in health education, using educational interventions as necessary tools for the reduction of the disease with the aim of reinforcing and stimulating the prevention and control of dengue.

OBJECTIVE

This study aims to evaluate the effectiveness of a nursing educational intervention for dengue control.

METHODS

A randomized controlled trial will be conducted with adults living in rural areas and participating in health promotion and disease prevention programs. We will enroll 116 adults. Adults will be randomized 1:1, with 58 adults assigned to the educational intervention group and 58 to the usual care group. Participants will receive 4 sessions over the course of a month, 1 week apart, and will be followed up for 1 month after the end of the educational intervention. Nursing Outcome Classification labels will be used to measure the outcomes: risk control (1902) and participation in health care decisions (1606).

RESULTS

The participants in the intervention group are expected to achieve better dengue control behaviors than those in the usual care group.

CONCLUSIONS

Risk factors are fostered by the community, largely caused by artificial reservoirs or unprotected tanks in homes; also, the lack of information hinders the identification of symptomatology and the poor implementation of effective measures, and the development of standardized educational strategies can contribute to efficient and cost-effective control of the disease.

CLINICALTRIAL

ClinicalTrials.gov NCT05321264; https://clinicaltrials.gov/study/NCT05321264

INTERNATIONAL REGISTERED REPORT

PRR1-10.2196/54286
Епітеліальний профіль рогівки і стабільність рефракції після ексимерлазерної корекції аметропії, виконаної на різних платформах
Authors: Panchenko Iu.O. , Putiienko O.O. , Kosuba S.I.
Published: November 2023

Актуальність. За даними 2020 року, 161 млн світової популяції мали аметропії, які пов’язані з помірними та тяжкими порушеннями зору або сліпотою. Лазерний кератомільоз in situ (LASIK) широко використовується у світі для корекції міопії, гіперметропії та астигматизму. Гіперметропічний профіль ексимерлазерної абляції призначений для збільшення кривизни центральної ділянки. Лазери попереднього покоління та попередні профілі абляції асоціювалися зі значним регресом, недокорекцією та втратою максимальної скоригованої гостроти зору на відстані. Оцінка профілю епітелію відіграє важливу роль для визначення механізму виникнення і ризиків регресу рефракційного результату. Мета: оцінити епітеліальний профіль рогівки і стабільність рефракції після ексимерлазерної корекції (ЕЛК) аметропії, виконаної на різних платформах. Матеріали та методи. Було проаналізовано медичну документацію 40 пацієнтів (80 очей), віком 18–40 років, яким з 2021 по 2023 р. проводили ЕЛК методом LASIK для корекції гіперметропії у медичному центрі «Лазер плюс» (м. Львів, Україна). До 1-ї групи увійшли 22 пацієнти (44 ока), яким було виконано ЕЛК методом LASIK для корекції гіперметропії за допомогою ексимерного лазера MEL 80 (Carl Zeiss Meditec). Групу 2 становили 18 пацієнтів (36 очей), яким виконували ЕЛК методом LASIK для корекції гіперметропії за допомогою ексимерного лазера MEL 90 (Carl Zeiss Meditec). Динамічні зміни оцінювались за допомогою контролю маніфестної рефракції, а також за картами товщини епітелію за результатами ОСТ рогівки. Термін спостереження — 1 рік. Результати. У групі 1 максимальна товщина епітелію фіксувалась на межі 5- і 7-міліметрової зони, а в групі 2 — на 7 мм. Різке збільшення товщини епітелію в обох групах фіксувалось у термін 3 місяці після LASIK. У 2-й групі найбільший приріст товщини був на 10 % меншим, ніж в 1-й групі. Незначний гіперметропічний зсув на термінах з 3-го місяця до 1 року. Статистично значущої різниці між результатами двох досліджуваних груп на різних термінах післяопераційного спостереження не відмічалось. Висновки. Поточне дослідження при даному об’ємі і тривалості показало, що результуючий профіль товщини епітелію є достатньо стабільним для підтримки необхідної сили заломлення рогівки протягом 1 року спостереження, але потрібний контроль цих параметрів на віддалених термінах, враховуючи різницю приросту товщини епітелію після LASIK на різних ексимерлазерних платформах — MEL 80 і MEL 90.
Developing Electronic Portfolios to Align with Diverse National Standards to Showcase Students’ and Teachers’ Performance: A Design Approach
Authors: FABUNMI Olaiya Kazeem , Ogunlade Oyeronke O.
Published: November 2023

Traditional methods of documenting and assessing educational performance and achievements have often been limited in scope and accessibility. Addressing these limitations is to leverage the potential of technology to create a comprehensive and user-friendly electronic portfolio (e-portfolio) system. This study aimed to investigate the required national standard and functionalities of e-portfolios for showcasing students’ and teachers’ performance. This study adopted qualitative research methods to investigate the context under study. Interviews, documents, and reports with and from students, lecturers, administrators, and educational experts provided insights into the specific requirements and expectations for an effective electronic portfolio system. One hundred twenty-five participants were randomly sampled for the study in the Abuja metropolis of Nigeria. Data were collected using a semi-structured interview and case study approach. A deductive approach was employed for the coding and analysis of the transcribed data. The findings identified several key features and functionalities required in an electronic portfolio system: Customizability and Flexibility, Alignment with Standards, Multimedia Capabilities, Reflection, and Goal-Setting Tools. Both students and teachers generally perceived the use of electronic portfolios positively. The respondents highlighted technological barriers, such as lack of necessary skills, limited access to devices or reliable internet connectivity; time constraints; and resistance to change as challenges in using e-portfolios to showcase their performance. Based on a systematic analysis of interview data from the respondents, the qualitative study offers a framework for exploring, understanding, and discussing the standard for and the impact of developing electronic portfolios for student and teacher performance.
Intersecting Traditions and Modernity: Perceptions of Quality Assurance in Outcome-Based Education among Vietnamese University Lecturers
Authors: Thuy Tran Thi , Thuy Pham Trut , Thao Le Thanh
Published: November 2023

In the continuously evolving landscape of global education, the role of Quality Assurance (QA) in fortifying and maintaining the relevance of teaching and learning processes has grown ever more critical. In this context, Vietnam—a country delicately balancing its rich traditions with a strong push towards modern educational paradigms—offers a unique vantage point. The primary aim of this study was to delve deep into Vietnamese university lecturers’ perceptions regarding the intersection of QA and Outcome-Based Education (OBE), particularly focusing on its ramifications on their academic practices. Adopting a qualitative methodology, we engaged with ten lecturers from two distinct universities in the Mekong Delta. Through semi-structured interviews, participants shared their narratives, which were subsequently analyzed using a thematic analysis approach. This analysis was enriched and contextualized through the lens of established theoretical frameworks. The emergent themes painted a multifaceted picture. While recognizing the transformative potential that QA can bring within the OBE framework, lecturers often found themselves grappling with the challenges of seamlessly integrating traditional teaching methodologies with the demands of OBE. Adding to this complexity were concerns about the potential erosion of the ‘human touch’ in teaching as technological interventions become more pervasive in QA processes. Another intriguing dimension was the interplay of deeply rooted Vietnamese cultural norms with contemporary QA practices, serving at times as barriers while at others as catalysts for innovation. The revelations from this study underscore the imperative for establishing culturally resonant QA systems, crafting comprehensive and contextual training modules, and ensuring a judicious blend of technology and traditional pedagogical practices. While resonating with universal themes in education, the findings also spotlight the nuances specific to Vietnam’s academic landscape, making a case for contextually tailored educational interventions.
Parental Influence on Career Choices of Navrongo Senior High School Students in the Kassena-Nankana Municipality
Authors: Anovunga Alfred Alunga
Published: November 2023

This study examined parental influence on the career choices of Navrongo Senior High School students in the Kassena-Nankana Municipality. The study sought to assess parental factors that contribute to the career choice of Navrongo Senior High School students in the Kasena Nankana Municipality, examine the effects of parental influence on the career choice of their children in Navrongo Senior High School, and find out the strategies that Navrongo Senior High School can adopt to assist students make informed career choice. Participants included in this study were 150 senior high school students. Stratified and simple random sampling techniques were used to select the sample size. Both open-ended and closed Likert Scale questionnaires were used for data collection. Percentages, bar charts, pie charts, and standard deviations were used to present the results. The result indicated that parents, in one way or the other, do influence their children in choosing careers. From the study, the respondents believed that when parents choose careers for their children, they do not enjoy their lifelong vocation. It was therefore recommended that the school solicit parents’ views when organizing career guidance for students, and parents should also be made aware of the negative consequences of their actions when they impose their opinions on their children when planning for their careers. Again, career programs should be introduced in Senior High Schools to assist students in making appropriate career choices.
Elements of a New Rhetoric in Foucault’s Work
Authors: Araújo Alex Pereira de
Published: November 2023

The principal objective of this study is to present and discuss the elements that emerge from Michel Foucault's archeological undertakings, which, in our view, configure the existence of a new rhetoric that deals with what the French philosopher called the rarefaction of the subject and rarefaction of discourse in his inaugural lecture at the Collège de France (Foucault, 1996). This new rhetoric would be in charge of reflecting and analyzing the phenomena that result from both the rarefaction of the subject and the rarefaction of discourse, that is, such rhetoric invests in what is responsible for imposing on the speaking subject what to say and how to say it. Therefore, it turns to certain mechanisms of control of discourses that Foucault presented in The Discourse on Language, a work that completes five decades of its publication. This Foucauldian rhetoric also has as its main function to deal with the history of the present, that is, to reflect on what we do and think at this exact moment, which, in turn, would be in charge of contributing to the history of how we became subjects in a culture like ours, at this stage of high modernity and the Information Age. From this perspective, she would be interested in the processes of identification and subjectivation that result from the ways in which we become subjects. In short, it is a study that seeks to present elements that demonstrate the emergence of a new rhetoric that emerges from the work of Michel Foucault, who, according to Deleuze (1992), increasingly invested in a generalized pragmatics.