bluuebunny/crossref_metadata_2025 huggingface dataset:
Kajian Karakteristik dan Evaluasi Pasca Huni Bangunan Pasar
Authors: Syadiah Lisna , Wibowo Danang Harito
Published: February 2020

This research examines in detail and academically the characteristics of the Paramount Modern Market, then conducts a post-occupational evaluation on the Paramount Modern Market building comprehensively. The object of study was chosen based on its location in the commercial superblock area, market design evolution, and in Gading Serpong commercial area there was an acceleration of economic growth. This study discusses the analysis of the application of the concept of green city in cluster dwellings in Gading Serpong. The method used in this study is a descriptive qualitative method that is carried out with a case study approach, as well as using inductive post-occupational evaluation techniques. The research found are the characteristics of the spatial, technical, and stylistic systems of the Paramount Market building are already efficient, quite in accordance with established rules, and can support trading activities on the market well and efficiently, and then the post-occupatonal evaluation results state that most of the elements in technical, functional and behavioral approaches are efficient and functioning optimally.
Tingkat Preferensi Pedestrian dan Walkability Koridor Jalan di Kota Tua Jakarta
Authors: Agradiana Pizza
Published: February 2020

Walkability is being a way to assess the environmental quality of walking activities. This study discusses the level of walkability in 6 main road corridors in the Kota Tua Jakarta area using scoring assessment methods on four aspects of the observed Walkability Level namely the level of security and safety, comfort level, the availability factor of pedestrian support facilities, and the quality factor or physical condition of pedestrian facilities the feet. From the results of the assessment, it is linked to the pedestrian preferences in choosing the walking route from the transit mode of transportation (train station and busway stop). With the location of the study on several road corridors in the Kota Tua Jakarta region, Jl. Pintu Besar Utara, Jl. Stasiun Kota, Jl. Lada, Jl. Jembatan Batu, Jl. Great South Door and Jl. Asemka. The results found that the level of walkability of a road does not always affect the user's walking preferences. Although the level of Walkability is high, it is not necessarily a pedestrian preference in the walking route.
Presence of viral haemorrhagic septicaemia virus (VHSV) in the environment of virus-contaminated fish farms and processing plants
Authors: Vennerström P , Maunula L , Välimäki E , Virtala AM
Published: February 2020

After the first outbreak of viral haemorrhagic septicaemia virus (VHSV) in Finnish brackish water rainbow trout Oncorhynchus mykiss farms, infection spread rapidly between the farms. The infrastructure of fish farming did not take into account spreading of infectious fish diseases. To show the presence of VHSV in the environment, we tested seawater, sediment and wild blue mussels Mytilus edulis from VHSV-infected fish farms, and liquid waste from a processing plant that handled infected rainbow trout. Additionally, blue mussels were bath-challenged with VHSV (exposed to cultivated virus or naturally infected rainbow trout). To detect VHSV, virus isolation in cell culture and real-time reverse transcriptase polymerase chain reaction (qRT-PCR) were used. The virus or viral RNA was detected in sea water and in liquid waste from processing plants during wintertime when water temperature is close to 0°C and sunlight is sparse. VHSV did not appear to replicate in blue mussels in our study. Therefore, blue mussels were not considered relevant carriers of VHSV. However, traces of viral RNA were detected up to 29 d post challenge in mussels. Contact with water from processing plants handling VHSV-infected fish populations increases the risk of the disease spreading to susceptible fish populations, especially during cold and dark times of the year.
Non-lethal diagnostic methods for koi herpesvirus in koi Cyprinus carpio
Authors: Soto E , Tamez-Trevino E , Yazdi Z , Stevens BN , Yun S , Martínez-López B , Burges J
Published: February 2020

Cyprinid herpesvirus 3, also known as koi herpesvirus (KHV), is a viral pathogen responsible for mass mortalities of carp worldwide. In this study, we compared the sensitivity and specificity of ELISA and quantitative PCR (qPCR) methods for the diagnosis of KHV in experimentally infected koiCyprinus carpioover an 11 mo period. Koi were exposed to KHV at 18 ± 1°C (permissive temperatures for KHV disease) in laboratory-controlled conditions. At 21 d post challenge, the temperature in the system was decreased to <15°C (non-permissive temperature for KHV disease), and fish were monitored for the following 11 mo. At different time points throughout the study, samples of blood and gills were collected from exposed and control koi and subjected to qPCR and ELISA. Survival proportions of 53.3 and 98.8% in exposed and control treatments, respectively, were recorded at the end of the challenge. Traditional receiver-operating characteristic analysis was used to compare the sensitivity of the ELISA and blood and gill qPCR during permissive and non-permissive temperatures. ELISA was superior to qPCR of gills and whole-blood samples in detecting previous exposure to KHV. Similar results were obtained in a second experiment exposing koi to KHV and inducing persistent infection at >30°C (non-permissive temperature for KHV disease). Finally, KHV ELISA specificity was confirmed using cyprinid herpesvirus 1-exposed koi through a period of 3 mo. This study demonstrates that the combination of ELISA and gill qPCR should be recommended in the diagnosis of KHV exposure of suspected carrier-state fish.
Effect of Sophoridine on Ca2+ Induced Ca2+ Release During Heart Failure
Authors: HU S.-T. , SHEN Y.-F. , GONG J.-M. , YANG Y.-J.
Published: February 2020

Sophoridine is a type of alkaloid extract derived from the Chinese herb Sophora ﬂavescens Ait (kushen) and possess a variety of pharmacological effects including anti-inﬂammation, anti-anaphylaxis, anti-cancer, anti-arrhythmic and so on. However, the effect of sophoridine on heart failure has not been known yet. In this study, the effect of sophoridine on heart failure was investigated using Sprague-Dawley (SD) rat model of chronic heart failure. Morphological results showed that in medium and high dose group, myofilaments were arranged orderly and closely, intermyofibrillar lysis disappeared and mitochondria contained tightly packed cristae compared with heart failure group. We investigated the Ca2+ induced Ca2+ transients and assessed the expression of ryanodine receptor (RyR2) and L-type Ca2+ channel (dihydropyridine receptor, DHPR). We found that the cytosolic Ca2+ transients were markedly increased in amplitude in medium (ΔF/F0=43.33±1.92) and high dose groups (ΔF/F0=47.21±1.25) compared with heart failure group (ΔF/F0=16.7±1.29, P<0.01), Moreover, we demonstrated that the expression of cardiac DHPR was significantly increased in medium- and high dose-group compared with heart failure rats. Our results suggest that sophoridine could improve heart failure by ameliorating cardiac Ca2+ induced Ca2+ transients, and that this amelioration is associated with upregulation of DHPR.
The Influence of Erythrocyte Maturity on Ion Transport and Membrane Lipid Composition in the Rat
Authors: VOKURKOVÁ M. , RAUCHOVÁ H. , DOBEŠOVÁ Z. , LOUKOTOVÁ J. , NOVÁKOVÁ O. , KUNEŠ J. , ZICHA J.
Published: February 2020

Significant relationships between ion transport and membrane lipid composition (cholesterol, total phospholipids and sphingomyelins) were found in erythrocytes of salt hypertensive Dahl rats. In these animals mean cellular hemoglobin content correlated negatively with Na+-K+ pump activity and Na+ leak but positively with Na+-K+ cotransport activity. Immature erythrocytes exhibit lower mean cellular hemoglobin content (MCHC) than mature ones. The aim of the present study was to find a relationship between erythrocyte maturity, membrane lipid composition and ion transport activity in Wistar rats aged three months which were subjected to repeated hemorrhage (blood loss 2 ml/day for 6 days) to enrich circulating erythrocytes with immature forms. Immature and mature erythrocyte fractions in control and hemorrhaged rats were separated by repeated centrifugation. Hemorrhaged rats had increased number of reticulocytes but reduced hematocrit and MCHC compared to control rats. Immature erythrocytes of hemorrhaged rats differed from mature ones of control animals by elevated Na+-K+ pump activity, reduced Na+-K+ cotransport activity and increased Rb+ leak. These ion transport changes in immature erythrocytes were accompanied by higher concentration of total phospholipids in their cell membranes. Membrane phospholipid content correlated positively with Na+-K+ pump activity and cation leaks but negatively with Na+-K+ cotransport activity. Moreover, they were also negatively related with MCHC which correlated negatively with Na+-K+ pump activity and Rb+ leak but positively with Na+-K+ cotransport activity. Thus certain abnormalities of erythrocyte ion transport and membrane lipid composition detected in hypertensive animals might be caused by higher incidence of immature cells.
Using a “Teaching Tolerance” Learning Plan in the Political Science Classroom
Authors: Gardner Michelle
Published: February 2020

Using the concept of racial capitalism, as well as several articles focusing on racism and the global environmental crisis both spurred by capitalism, I attempt to have students link materials from an introductory political science class on race and ethnicity politics via a “Teaching Tolerance” Learning Plan. “Teaching Tolerance” is a project of the Southern Poverty Law Center dedicated to critical race consciousness in K-12 classroom, but I make use of the learning plan in the university classroom as a means of increasing racial consciousness amongst university students and teaching them how to connect sociopolitical racial histories to the concept of racial capitalism.
Unusually huge traumatic or irritation fibroma –A case report.
Authors: Agarwal Mudit , R Muthunagai , R Sivasankary
Published: February 2020

Oral mucosa frequently encounters exophytic growth. Traumatic or irritation fibroma is a benign exophytic oral lesion that develops secondary to tissue.It is the benign reactive lesion, and the treatment of choice is surgical excision.In this case report we present a case of unusually large irritation or traumatic fibroma in left buccal mucosa.

Key Words : Taumatic fibroma , Irritation fibroma , Benign tumour , Pedunculated growth
The Use of Natural Agents to Counteract Telomere Shortening: Effects of a Multi-Component Extract of Astragalus mongholicus Bunge and Danazol
Authors: Guinobert Isabelle , Blondeau Claude , Colicchio Bruno , Oudrhiri Noufissa , Dieterlen Alain , Jeandidier Eric , Deschenes Georges , Bardot Valérie , Cotte César , Ripoche Isabelle , Carde Patrice , Berthomier Lucile , M’Kacher Radhia
Published: February 2020

A link between telomere shortening and oxidative stress was found in aging people and patients with cancer or inflammatory diseases. Extracts of Astragalus spp. are known to stimulate telomerase activity, thereby compensating telomere shortening. We characterized a multi-component hydroethanolic root extract (HRE) of Astragalus mongholicus Bunge and assessed its effects on telomeres compared to those of danazol. Astragalosides I to IV, flavonoids, amino acids and sugars were detected in the HRE. Samples of peripheral blood lymphocytes with short telomeres from 18 healthy donors (mean age 63.5 years; range 32–86 years) were exposed to a single dose of 1 µg/mL HRE or danazol for three days. Telomere length and telomerase expression were then measured. Significant elongation of telomeres associated to a less toxicity was observed in lymphocytes from 13/18 donors following HRE treatment (0.54 kb (0.15–2.06 kb)) and in those from 9/18 donors after danazol treatment (0.95 kb (0.06–2.06 kb)). The rate of cells with short telomeres (<3 kb) decreased in lymphocytes from all donors after exposure to either HRE or danazol, telomere elongation being telomerase-dependent. These findings suggest that the HRE could be used for the management of age-related diseases.
Understanding Exercise Adherence: The Predictability of Past Experience and Motivational Determinants
Authors: Rodrigues Filipe , Teixeira Diogo , Neiva Henrique , Cid Luís , Monteiro Diogo
Published: February 2020

Background: An unresolved debate lingers over the effect of past behavior on motivational patterns and future behavior stability in the exercise context. Theorists argue that past behavior has a residual effect on future behavior; however, empirical studies have shown that past behavior displays significant power in predicting behavior recurrence in the future. The present research aimed to examine the effect of past behavior and motivational determinants on future exercise adherence. Methods: Data from 437 Portuguese gym exercisers (female = 235; male = 202) aged between 18 and 53 years (M = 31.14; SD = 9.47), with exercise experience ranging from 6 to 12 months (M = 9.41; SD = 1.33) were considered for research. Participants completed a multi-section survey measuring interpersonal behaviors, basic psychological needs, behavioral regulations, and intentions. Data from past behavior and future exercise adherence were collected using computerized records of their attendance at the gym. Results: Positive and significant correlations paths were evidenced among perceived supportive behaviors, needs satisfaction, autonomous motivation, intentions and future exercise adherence. Similar results were presented among perceived thwarting behaviors, needs frustration, and controlled motivation. Regression paths showed that perceived supportive behavior, basic needs satisfaction, and autonomous motivation displayed positive and significant effects on future behaviors; thus, past behavior displayed the highest coefficient on future exercise adherence. Fitness professionals should aim at creating supportive environments, thus, improving the likelihood of being perceived by exercisers as need-supportive individuals. By doing so, as a result, exercisers would experience increased levels of autonomous motivation and higher rates of future exercise attendance at the gym. Hence, exercisers will gradually form their positive past exercise experience, increasing the probability of engaging in an exercise in the future.
Synthesis and Cytotoxicity Studies on Ru and Rh Nanoparticles as Potential X-Ray Fluorescence Computed Tomography (XFCT) Contrast Agents
Authors: Li Yuyang , Shaker Kian , Svenda Martin , Vogt Carmen , Hertz Hans M. , Toprak Muhammet S.
Published: February 2020

X-Ray fluorescence computed tomography (XFCT) is an emerging biomedical imaging technique, which demands the development of new contrast agents. Ruthenium (Ru) and rhodium (Rh) have spectrally attractive Kα edge energies, qualifying them as new XFCT bio-imaging probes. Metallic Ru and Rh nanoparticles are synthesized by polyol method, in the presence of a stabilizer. The effect of several reaction parameters, including reaction temperature time, precursor and stabilizer concentration, and stabilizer molecular weight, on the size of particles, were studied. Resultant materials were characterized in detail using XRD, TEM, FT-IR, DLS-zeta potential and TGA techniques. Ru particles in the size range of 1–3 nm, and Rh particles of 6–9 nm were obtained. At physiological pH, both material systems showed agglomeration into larger assemblies ranging from 12–104 nm for Ru and 25–50 nm for Rh. Cytotoxicity of the nanoparticles (NPs) was evaluated on macrophages and ovarian cancer cells, showing minimal toxicity in doses up to 50 μg/mL. XFCT performance was evaluated on a small-animal-sized phantom model, demonstrating the possibility of quantitative evaluation of the measured dose with an expected linear response. This work provides a detailed route for the synthesis, size control and characterization of two materials systems as viable contrast agents for XFCT bio-imaging.
Protective Effect of Cicer arietinum L. (Chickpea) Ethanol Extract in the Dextran Sulfate Sodium-Induced Mouse Model of Ulcerative Colitis
Authors: Kim Mia , Chung Kyung-Sook , Hwang Se-Jung , Yoon Ye Seul , Jang Young Pyo , Lee Jong Kil , Lee Kyung-Tae
Published: February 2020

Inflammatory bowel disease (IBD) is a major risk factor of colorectal cancer. Drugs currently used for IBD exhibit adverse effects including vomiting, nausea, and diarrhea. Naturally derived novel alternative therapies are required to overcome these limitations. In this study, we investigated the protective effects of ethanol extract of Cicer arietinum (CEE) in a dextran sodium sulfate (DSS)-induced mouse model of colitis. CEE markedly improved DSS-induced clinical symptoms and histological status, such as the disease activity index, spleen weight, and colon length. Moreover, CEE-treated mice showed significant recovery of DSS-induced crypt damage and cell death. CEE suppressed myeloperoxidase (MPO) activity and macrophage marker F4/80 mRNA expression in colonic tissue of mice with DSS-induced colitis, indicating neutrophil infiltration and macrophage accumulation, respectively. Although DSS upregulated pro-inflammatory mediators and activated transcription factors, CEE downregulated the mRNA expression of cytokines including interleukin-6, interleukin-1β, and tumor necrosis factor-α, protein expression of cyclooxygenase-2 and inducible nitric oxide synthase, as well as activation of nuclear factor-kappa B (NF-κB) and signal transducer and activator of transcription 3 (STAT3). Hence, our findings reveal that the anti-inflammatory properties of CEE, involving the downregulation of the expression of pro-inflammatory mediators by inactivating NF-κB and STAT3 in DSS-induced colitis mice.
A New Vacuum Pressure Infiltration CFRP Method and Preparation Experimental Study of Composite
Authors: Ma Yuqin , Wang Jie , Zhao Yatao , Wei Xinliang , Ju Luyan , Chen Yi
Published: February 2020

In order to prepare a carbon-fiber-reinforced polymer composite (CFRP) with ideal microstructure and properties, a new vacuum pressure infiltration CFRP method is proposed based on an analysis of existing CFRP preparation process methods. Research on composite material preparation systems was carried out by using this new method principle. The system mainly includes a fiber pre-forming module, a vacuum heating infiltration module, a hot-press curing molding module, and a data acquisition control module. Under the conditions of natural curing at 0 MPa + 6 h + 25 °C, vacuum heating curing at –0.05 MPa + 30 min + 80 °C, and hot-press curing at 0.7 MPa + 5 min + 50 °C, a two-dimensional (2D) CFRP with excellent microstructure and properties was successfully prepared. Observing the microstructure of the prepared composite material, it can be found that the inside of the composite material was sufficiently and uniformly infiltrated, and common preparation defects such as holes and delamination were effectively controlled. Through the performance test, the bending strength of the material reached 790 MPa.
Pyrolytic Kinetics of Polystyrene Particle in Nitrogen Atmosphere: Particle Size Effects and Application of Distributed Activation Energy Method
Authors: Jiang Lin , Yang Xin-Rui , Gao Xu , Xu Qiang , Das Oisik , Sun Jin-Hua , Kuzman Manja Kitek
Published: February 2020

This work was motivated by a study of particle size effects on pyrolysis kinetics and models of polystyrene particle. Micro-size polystyrene particles with four different diameters, 5, 10, 15, and 50 µm, were selected as experimental materials. Activation energies were obtained by isoconversional methods, and pyrolysis model of each particle size and heating rate was examined through different reaction models by the Coats–Redfern method. To identify the controlling model, the Avrami–Eroféev model was identified as the controlling pyrolysis model for polystyrene pyrolysis. Accommodation function effect was employed to modify the Avrami–Eroféev model. The model was then modified to f(α) = nα0.39n − 1.15(1 − α)[−ln(1 − α)]1 − 1/n, by which the polystyrene pyrolysis with different particle sizes can be well explained. It was found that the reaction model cannot be influenced by particle geometric dimension. The reaction rate can be changed because the specific surface area will decrease with particle diameter. To separate each step reaction and identify their distributions to kinetics, distributed activation energy method was introduced to calculate the weight factor and kinetic triplets. Results showed that particle size has big impacts on both first and second step reactions. Smaller size particle can accelerate the process of pyrolysis reaction. Finally, sensitivity analysis was brought to check the sensitivity and weight of each parameter in the model.
Preparation of Ethylene Glycol Dimethacrylate (EGDMA)-Based Terpolymer as Potential Sorbents for Pharmaceuticals Adsorption
Authors: Shaipulizan Nur Syafiqah , Md Jamil Siti Nurul Ain , Kamaruzaman Sazlinda , Subri Nur Nida Syamimi , Adeyi Abel Adekanmi , Abdullah Abdul Halim , Abdullah Luqman Chuah
Published: February 2020

Ethylene glycol dimethacrylate (EGDMA) is used as a crosslinker in poly(acrylonitrile (AN)-co-vinylbenzyl chloride (VBC)) to investigate the effect of long-chain crosslinker to the porosity of the terpolymer system. Poly(AN-co-EGDMA-co-VBC) is synthesized by using precipitation polymerization method and further hypercrosslinked by Friedel-Crafts reaction. FT-IR spectra of poly(AN-co-EGDMA-co-VBC) show that the absorption bands at ~1290 cm−1 that are assigned to the C–Cl vibrations are almost disappeared in hypercrosslinked (HXL) poly(AN-co-EGDMA-co-VBC) polymers, confirming that the hypercrosslinking reaction is successful. SEM images show that the morphologies of the polymers are retained through the hypercrosslinking reactions. Brunauer–Emmett–Teller (BET) analysis shows that hypercrosslinked polymers had a specific surface area up to 59 m2·g−1. The preliminary performance of the terpolymer adsorbent to capture polar analyte is evaluated by adsorbing salicylic acid and mefenamic acid from aqueous solution in a batch system. The maximum adsorption capacity of salicylic acid and mefenamic acid were up to 416.7 mg·g−1 and 625 mg·g−1, respectively, and the adsorption kinetic data obeyed pseudo-second-order rate equation.
Effect of Silver Nanoparticles on the Microstructure, Non-Isothermal Crystallization Behavior and Antibacterial Activity of Polyoxymethylene
Authors: Zeng Yicheng , Liu Yang , Wang Lumin , Huang Hongliang , Zhang Xun , Liu Yongli , Min Minghua , Li Ying
Published: February 2020

Silver (Ag) nanoparticles were synthesized by a facile route in the presence of oleic acid and n-propylamine. It was shown that the average primary size of the as-synthesized Ag nanoparticles was approximately 10 nm and the surface of as-synthesized Ag nanoparticles was capped with monolayer surfactants with the content of 19.6%. Based on as-synthesized Ag nanoparticles, polyoxymethylene (POM)/Ag nanocomposites were prepared. The influence of Ag nanoparticles on non-isothermal crystallization behavior of POM was investigated by differential scanning calorimetry (DSC). The Jeziorny, Jeziorny-modified Avrami, Ozawa, Liu and Mo, Ziabicki and Kissinger models were applied to analyze the non-isothermal melt crystallization data of POM/Ag nanocomposites. Results of half time (t1/2), crystallization rate parameter (CRP), crystallization rate function (K(T)), kinetic parameter (F(T)), the kinetic crystallizability at unit cooling rate (GZ) and the crystallization activation energy (∆E) were determined. Small amounts of Ag nanoparticles dispersed into POM matrix were shown to act as heterogeneous nuclei, which could enhance the crystallization rate of POM, increase the number of POM spherulites and reduce POM spherulites size. However, the higher loading of Ag nanoparticles were easily aggregated, which restrained POM crystallization to some degree. Furthermore, the POM/Ag nanocomposites showed robust antibacterial activity against Escherichia coli and Staphylococcus aureus.
Étude archéométallurgique de parures hallstattiennes en alliage cuivreux du Rhin supérieur
Authors: Tremblay-Cormier Laurie , Mille Benoît
Published: February 2020

La vallée du Rhin supérieur se distingue, au premier âge du Fer, par une production métallique caractéristique ; la présente étude a pour objectif d’en approfondir la définition, en complétant l’analyse des formes par celle des traditions métallurgiques. Elle vise également à combler un déficit de la recherche sur les alliages cuivreux, où l’âge du Fer est encore faiblement représenté. Un corpus de parures de types régionaux a été sélectionné (bracelets de type Bade-Alsace, parures annulaires massives de section circulaire, fermées et lisses), couvrant une large période allant du Ha C2 au Ha D3, soit du viie au milieu du

ve siècle avant notre ère. Le protocole est basé sur l’étude macroscopique des parures et l’analyse de leur composition élémentaire, avec pour objectif d’établir différents types de composition chimique et d’en proposer une interprétation archéologique. Les analyses ont été réalisées au Centre de recherche et de restauration des musées de France (C2RMF) à l’aide de la méthode PIXE, principalement sur des prélèvements faits dans les parties saines des parures. Les résultats montrent de nettes différences de composition chimique selon la typologie ; les bracelets de type Bade-Alsace sont ainsi réalisés suivant la recette classique du bronze à l’étain et montrent une variation du spectre d’impuretés qui dépend principalement de la forme du bracelet (variantes A1, B1 et B2). À l’inverse, de nombreuses parures fermées lisses possèdent un taux élevé de plomb, allant jusqu’à 36 %. Ce phénomène pose la question des raisons qui motivent cette forte présence du plomb dans l’alliage ; un rôle plus économique que technique peut être invoqué, avec une volonté d’augmenter la masse globale de métal par l’adjonction de plomb au bronze recyclé. La pratique des bronzes au plomb trouverait ici pour explication l’appauvrissement des stocks de matière première, et traduirait ainsi des changements profonds dans les dynamiques économiques, touchant plus particulièrement aux ressources disponibles. L’analyse est complétée par la recherche des compositions jumelles, qui correspondent à des objets présentant une composition chimique identique. La mise en évidence de jumeaux de lingot et de creuset permet de proposer l’existence de liens d’ordre technologique entre certaines pièces, qui appartiennent parfois à des ensembles ou à des sites différents. Leur distribution dans l’ensemble du Rhin supérieur, autant sur ses deux rives que dans ses parties nord et sud, atteste l’existence d’un réseau de relations soutenues entre les artisans et la population. L’homogénéité des traditions métallurgiques va ainsi de pair avec celle de la typologie, ajoutant à la cohésion déjà forte de la culture matérielle du Rhin supérieur.
Un village chasséen dans le Sud de la France: Cazan «le Clos du Moulin», Vernègues (Bouches-du-Rhône)
Authors: Moreau Clément , Léa Vanessa , Delhon Claire , Magnin Frédéric , Howarth Luke , Linton Jimmy , Pacotte Lucas , Foucras Sylvain , Nicosia Cristiano , Le Bourdonnec François-Xavier , Gerez Julie , Sénépart Ingrid
Published: February 2020

Une fouille réalisée en 2013 à Cazan «le Clos du Moulin » Vernègues (Bouches-du Rhône) a permis de mettre en évidence une importante occupation du Chasséen récent en fond de vallon. Aucun niveau de sol n’a été retrouvé, mais plus de 600 structures en creux permettent de documenter un des premiers sites d’habitat structuré de cette période dans le Sud de la France. Les attributions chronologiques reposent sur huit datations au 14C comprises en 4100 et 3800 avant notre ère et sur un abondant mobilier archéologique qui concorde avec l’attribution à une étape récente du Chasséen. Le gisement livre plusieurs fosses, des puits et une concentration de structures à pierres chauffées, mais aussi et surtout de nombreux trous de poteau et fosses d’implantation qui permettent de restituer les plans d’environ quinze bâtiments. Ces derniers correspondent notamment à dix édifices standards ; trois ensembles architecturaux plus imposants s’insèrent au sein de cette organisation et traduisent sans doute la présence d’édifices socialement plus valorisés. L’analyse du mobilier archéologique ne permet pas de déterminer assurément de chronologies relatives au sein de ces structures et aménagements, mais elle met en évidence plusieurs zones d’activités privilégiées en particulier pour le travail du silex et de l’obsidienne. Ces activités signent une occupation domestique a priori pérenne au sein d’un paysage largement anthropisé et maitrisé d’après les observations anthracologiques et malacologiques. L’ensemble de ces résultats tend à prouver l’attachement des populations chasséennes à ce territoire où elles se sont installées et ont vécues. Ce site permet donc enfin d’approcher pleinement la notion de village pour le Chasséen récent.
Parures et territoires à la fin de l’âge du Bronze: les bracelets du groupe d’Orgon dans le Sud-Est de la France
Authors: Lachenal Thibault
Published: February 2020

Cette étude s’intéresse à une variété de parure annulaire dont l’originalité se devait d’être soulignée, qu’il est proposé de nommer bracelets du groupe d’Orgon en référence au dépôt de Notre-Dame de Beauregard, dans cette localité des Bouches-du-Rhône, qui en a livré le plus grand nombre. Ce groupe est illustré par quarante objets provenant de douze sites répartis dans quatre départements du Sud-Est de la France. Il correspond à des bracelets ouverts, de tige mince à section en D aplati dont les extrémités sont ornées de bourrelets transversaux. Les contextes de découvertes de ces objets, de nature variée (habitats, dépôts et nécropoles) convergent vers une datation de leur production au Bronze final 3b et éventuellement lors de la phase de transition entre l’âge du Bronze et l’âge du Fer, aux ixe et viiie s. av. J.-C. Ces parures sont munies de décors couvrant la totalité du jonc et présentant une certaine variabilité en fonction de la technique utilisée et des motifs représentés. Leur combinaison permet de définir 3 types qui s’excluent géographiquement, la majorité des exemplaires de chacun d’entre eux se concentrant dans un cercle ne dépassant pas les 50 km de diamètre. Ces différences peuvent signaler l’existence de trois ateliers spécialisés possédant chacun un type d’ornementation spécifique. Plusieurs indices, comme un moule, témoignent en effet d’une production locale de ces objets. Les bracelets de même type provenant du dépôt de Notre-Dame de Beauregard et de la nécropole des Lauzières à Lourmarin dans le Vaucluse présentent par ailleurs des signatures élémentaires semblables, qui laissent penser qu’ils proviennent d’un même atelier. Une autre hypothèse expliquant la production de ces types est que ces décors furent les supports d’expressions identitaires et que leur zone de répartition principale corresponde à un territoire communautaire. Une bonne correspondance peut en effet être établie entre la répartition de ces objets et les styles céramiques du bassin inférieur du Rhône à l’extrême fin de l’âge du Bronze. Localisées à distance des ressources en cuivre des Alpes et du Sud du Massif central, ces sociétés ne sont néanmoins pas dépourvues d’une production métallurgique propre, dont les bracelets du groupe d’Orgon constituent les témoins les plus directs.
Changements technologiques pendant l’Holocène dans le bassin de l’Èbre. Stratégies de production et de gestion de l’industrie lithique d’Atxoste (Álava, Espagne)
Authors: Soto Sebastián Adriana
Published: February 2020

Ces dernières décennies ont été marquées par une augmentation significative de l’intérêt porté aux sociétés de la fin du Pléistocène et du début de l’Holocène dans la péninsule Ibérique. Dans ce contexte, le bassin de l’Èbre a fait l’objet de programmes de recherche intensifs qui ont permis d’approfondir, d’une part, la compréhension des modes de vie des dernières sociétés de chasseurs-cueilleurs et, d’autre part, l’établissement de la dynamique chronoculturelle de la région. Aujourd’hui, cette dynamique est subdivisée en quatre phases : l’Épipaléolithique microlaminaire ou Épimagdalénien, le Sauveterrien microlaminaire ou Sauveterroïde, le Mésolithique à encoches et denticulés et le Mésolithique géométrique. L’objectif de cet article est de caractériser les industries lithiques du site d’Atxoste et d’apporter de nouvelles données technologiques sur chacune de ces traditions, afin d’affiner notre connaissance des changements technologiques. Pour cela, nous présenterons les principaux résultats des études relatives aux matières premières, à la technologie et à la typologie des ensembles lithiques des niveaux épipaléolithiques (VIb2 et VIb) et mésolithiques (VI, V, IV et IIIb2) du gisement d’Atxoste (Vírgala, Álava, Espagne), et nous les intégrerons dans le contexte régional du bassin de l’Èbre. Les résultats montrent que chacune des traditions lithiques répond à des objectifs et à une organisation particulière du système lithique. Ces nouvelles données mettent en évidence l’adoption et le développement de différentes stratégies et procédures technologiques en vue de l’obtention d’un équipement lithique varié. Autant d’éléments nouveaux qui permettent de mieux comprendre les dernières sociétés de chasseurs-cueilleurs.
La théologie du processus et la doctrine de Dieu
Authors: Cobb John B.
Published: February 2020

By a process theology » is understood the application to the field of theology of the process philosophy of A.N. Whitehead. A mathematician and a logician to start with, Whitehead developed a philosophical cosmology which links in depth the reality of the world and that of God. This article begins with a brief description of the Chicago Divinity School, established at the end of the nineteenth century and where Whitehead's thought found a special echo from the late twenties to the middle fifties, mostly under the influence of H.N. Wieman and Ch. Hartshorne. It goes on to express some of Whitehead's key ideas, centring around the doctrine of God, and concludes with a comparison between process theology and Buddhist thought.
Planning of the Web-based E-Raport Assessment System
Authors: Febriyanto Erick , Naufal Romzi Syauqi , Sulistiawati Sulistiawati
Published: February 2020

In the world of information technology has changed the lifestyle in the aspect of our lives especially in the educational world. E-Raport is an academic information system used to input web-based student value data. The current value data input system is a benchmark for the creation of quality output and able to compete with other schools. One of the benchmarks that can be the competitiveness for other schools is the result of student learning assessments that are handled by each class. Problems that occur in the input of the value of Raport at SDN Sukanagara is currently still a manual that is the value of Raport recorded in the book Raport, so it takes a long time and a lot of energy needed. Research has the purpose of designing a value information system that facilitates the checking, recording and reporting of the computerized value of the students. Computerized Raport value reports can minimize errors in student data processing. This WEB based online raport is very easy data information and can be accessed anytime and anywhere, the system design works to insert and save value Report data and attendance and display info from school. The system uses data collection methods such as interviews, library studies, and system design, which are context diagrams, and prototypes. The information system of online Raport SDN Sukanagara is expected to be able to bring positive impact to the educational world, especially for SDN Sukanagara in the development of information technology applied in the world of education.
KARYOLOGICAL STUDY IN THE CHILEAN RHATANY Krameria cistoidea HOOK. & ARN. (KRAMERIACEAE)
Authors: Palma Rojas C. , Jara Seguel P. , García M. , von Brand E. , Araya Jaime C.
Published: February 2020

The karyotype of the plant species Krameria cistoidea Hook. & Arn. was studied by assessing chromosome characters such as morphology, size, and C-banding pattern. The karyotype of K. cistoidea was composed only by metacentric chromosomes in the two populations studied. The haploid set length was 51.9±2.3 µm and the mean chromosome size was 8.68±0.78 µm. Some similarities in chromosome morphology and size can be observed among K. cistoidea and K. triandra, in addition to the chromosome number 2n=12 which is conserved within the genus. K. cistoidea exhibited a symmetric banding pattern with large C-bands in the telomeres of the short and long arms of all chromosomes, except the short arm of pair 1. The relative length of the C-bands was 23.5% of the total haploid set length. These cytological results on K. cistoidea are the first data on quantitative karyotype morphology and C-banding patterns in the genus Krameria. Key words: Krameria, karyotype, C-banding
TP53 PATHOGENIC VARIANTS RELATED TO CANCER
Authors: Rosero C.Y. , Mejia L.G. , Corredor M.
Published: February 2020

TP53 or P53 is a tumor suppressor gene known as the “genome guardian”, responsible for inducing cell response to DNA damage, by stopping the cell cycle in case of mutation, activating DNA repair enzymes, initiating senescence and activation of apoptosis. Mutations in the gene sequence can cause non-synonymous mutations or errors in the reading frame by insertion, deletion or displacement of nucleotides: e.g., c.358A>G mutation in exon 4 and variants located in exons 9 and 10 of the TD domain. Therefore, in this review, we will see that changes in the reading frame, including the loss of one or two base pairs could prevent accurate transcription or changes in the structure and function of the protein, and could completely impair reparation function. These changes promote self-sufficiency in growth signaling, insensitivity to anti-growth signals, and evasion of apoptosis, resulting in limitless replication and induction of metastatic angiogenesis, generating as a consequence the proliferation of tumor, neoplastic, and lymphoid cells. Taking into account the importance of TP53 in the regulation of the cell cycle, the objective of this review is to update information related to the role of this gene in the development of cancer and the description of genetic variations. Key words: Neoplasms, nuclear phosphoprotein p53, Tumor Suppressor, mutation, Clinvar, Uniprot
Simulating of the Flood Runoff in Case of Heavy Rains in the Zone of Many-year Frozen Earths
Authors:   Bolgov M.V., Boyarintsev Y.L., Filimonova M.K.
Published: February 2020

Special features of the rain floods runoff formation and an approach to their simulating for small catchments of the zone of many-year frozen earths’ spreading are discussed. Information about heavy rains and resulted floods obtained from the observation data from the experimental catchments of the Kolyma and Bomnak runoff stations has been used as initial data. On the basis of the available concepts of the many-year frozen earths’ active layer dynamics and the outcomes of the different years’ experimental investigations, a mathematical model has been proposed. It enables to take into consideration the accumulating role of the soil melted layer and the moss cover. The НЕС-HMS simulating system able to reproduce the flood runoff course with the 1 hour time discontinuity in specific conditions of slope regulation on the basis of the Clark unit hydrograph method was used to take in account special features of the rain runoff formation.
Experience in Pilotless Aircrafts’ Application for Assessment of the Surface Water Bodies’ Bank State
Authors:   Luchnikov A.I., Lyakhin Y.S., Lepikhin A.P.
Published: February 2020

Experience of the pilotless aircrafts application for decision of tasks connected with surface water bodies’ bank stripe condition and dynamics assessment has been discussed. In order to increase substantially the survey and subsequent estimations accurancy the use of reference points (markers) has been proposed, with determining of the plane and altitude coordinates with professional two-frequency GPS-GLONASS recievers in accordance with the standing regulating documants. This approach will enable to improve drastically quality of the obtained assessments and efficiency of the pilotless aircraft application. Analysis of the slope reforming intensity has been carried out at the range of the Kosva River right bank in the vicinity of the villige of Peremskoye on the basis of the 2017 field investigations outcomes. Such estimations are necessary for effective forecasting of bank changes dynamics, as well as for designing of any bank protection measures.
Contemporary Problems of the Surface Waters Quality Assessment, Regulating and Monitoring
Authors:   Venitsianov Y.V., Adzhiyenko G.V., Voznyak A.A., Chiganova M.A.
Published: February 2020

Water resources protection and rehabilitation to the ecologicallly favorable living condition is one of the main tasks of Water Strategy of the RF till 2020. This task cannot be considered fulfilled. This article analyses the reasons of the situation. Several broblems are discussed: insufficient scientific support of the natural waters quality assessment methods, state of the quality management (regulating) system, lack of the advanced and adequate monitoring system, and lack of funding for the purposes of water protection. It has been shown that scientific/methodological basis for natural waters quality assessment and management focused on the MPC system and the discharges statistics according to the 2-TP (vodkhoz) pattern is obsolete and out-dated. No monitoring of micro-pollutants, zenobiotic first of all, is done. Practically, there is no monitoring of bottom sediments. Thechnology of hydro/chemical information processing is not developed. Any requirements to the disposed water quality should take into account the background concentrations different for water bodies located in different physical/geographic and climatic zones. The order of procedure for transition from the current discharge regulation system on the basis of NDS to the system based on NDT is not worked out. There are no norms of the pollutants content in bottom sediments. It has been proposed to apply information techniques for assessment of the xenobiotic pollution on the basis of the biological activity forecast for PASS and GUSAR compounds. All units of the water sector are to use computer information/calculating systems provided with the advanced model of water basins and their sections in order to change radically the situation with water sector funding. It seems that one of the possible ways of the water quality regulating problems is the transition to the risk-oriented approach which is actively used in the legislative regulation systems of the developed countries.
Environmental/hydrological problems of the Mekong River Delta
Authors:   Tran Huynh Thao
Published: February 2020

The article shows how anthropogenic impacts on the hydrological regime in the upper part of the river basin together with climatic changes lead to an ecological catastrophe in the delta of the river. We have considered the Mekong River basin, which is located on the territory of six countries, where more than 30 hydroelectric power stations are already operating in the upper part of the basin, and another 10 are under construction. The number of hydroelectric power stations in the basin is planned to be increased to 170. The Mekong River Delta, completely located on the territory of Vietnam, is experiencing huge multifaceted problems. The delta has been growing towards the sea for many centuries, but in recent decades it has been receding, primarily due to a sharp decrease in the inflow of sediment in the delta, which is detained by numerous dams upstream. Uncontrolled until recently the extraction of sand and gravel mixtures from the riverbed also has an impact. On the other hand, the construction of hydraulic structures is not only a very important factor in the economic development of the basin countries, but also an important tool in combating the growing contrast of the climate, when floods are becoming more powerful, and the decline of the runoff in the dry period is becoming lower. Reduction of low-water runoff is exacerbated by the pumping out of groundwater for the needs of water supply. Reduction of the solid flow and low-water flow against the background of the growth of the world ocean level caused by climate change leads to a significant penetration of sea salt waters along the canal and channel systems into the delta. This has an extremely adverse effect on crop production and fish farming. At the same time, the Mekong Delta is the most important agricultural sector in Vietnam, accounting for more than 50% of total rice production and 60% of fish production. An article is devoted to the investigation of these problems and the identification of ways to solve them.
On the Issue of the Geographical Information Systems as a Form of the State Water Registry Development (the Mzymta River model as a study case)
Authors:   Zheleznyak N.M.
Published: February 2020

The article considers the issues of the state water registry formation, its current state analysis, composition of information and ways of its input. The results of the study make it possible to state that in its current form the state water registry does not correspond to the realities of the time. Analysis of private and official applications to the Federal Agency of Water Resources territorial bodies has demonstrated that the State Water Register in its current state cannot satisfy the most of the supplied inquiries. Among other problems, it is hardly possible to identify water bodies in terms of their location, this inevitably increases risks of these water bodies degradation. The article also provides recommendations for arranging the State Water Registry in the form of a map, combining the resources of automated information systems “State Water Registry” and “State Monitoring of Water Objects” and establishing a public service “Public Water Registry”. In addition, a new form of the state water register “1.9-gvr M – Water objects explored” has been developed; Using the example of the Mzymta River, a model of a new state water registry has been developed.