bluuebunny/crossref_metadata_2025 huggingface dataset:
Central governance and minority rights: The case of the developing country
Authors: Mustafa Liburn , Morina Mensur
Published: December 2022

The purpose of the paper is to study the institutional approach of the Serbian state toward ethnic minorities, specifically towards the Albanian ethnic minority in Serbia. The research focuses on the Serbian state governance forms and how these forms reflect on local governance policies by the Albanian majority. The deprivation of many individual and national rights has influenced the strengthening of the national identity (Searle-White, 2001). The paper is a theoretical study that is based on the qualitative research method and includes the discourse analysis of programs, events, writings, and statements of intellectual and political figures of the relevant times. The paper finds out that the violation of freedom and national rights toward the Albanian minority in Serbia has reflected strong forms of political behavior. In conclusion, it turns out that the Albanian political class in Serbia, disappointed by the state institutions, seeks the help of the mother state of Kosovo so that the status of the Albanians in Serbia is resolved the same as the status of the Serbs of Kosovo. This paper seeks to contribute to central government relations with ethnic minorities as well as making a non-prejudiced approach to the freedoms and rights of ethnic minorities in general
What explains the rural-urban inequalities in maternal health services utilization in Tanzania? a Fairlie decomposition analysis analysis
Authors: Ntegwa Magashi J. , Mcharo Evaline G. , Mlay Joseph F.
Published: December 2022

Background: Maternal mortality remains a public health issue in
developing countries, with rural areas having higher rates compared to
urban areas. Since effective utilization of maternal health services has
the potential to reduce maternal mortality, this study measures the
factors contributing to the existing rural-urban differences in the
utilization of maternal health services in Tanzania Methods: We
used Tanzania Demographic and Health Survey 2015/2016 data. Multi-stage
stratified sampling was used to select study participants and we
estimated a Fairlie decomposition to understand factors that contribute
to inequality in maternal health services utilization between rural and
urban areas in Tanzania using Stata 17. Results: The study
findings revealed a considerably wide rural-urban disparity in the
utilization of maternal health services. As the findings indicated,
household wealth status is the major factor for that disparity. Other
factors are women’s exposure to the media, women’s working status, and
distance from the homesteads to the health facilities.
Conclusion: Therefore, any policy geared toward bridging the
gap between rural and urban areas in the utilization of maternal health
services should focus on empowering women in terms of household economic
status, media exposure, and employment.
EPS8L1 promotes migration and metastasis of ovarian cancer by activating Rac1/MAPK signaling pathway via upregulating TIAM2
Authors: Wang Yuting , Zhang Lei , Luo Xianqiang , Wang Meichen , Luo Min , Zhou Hongyu , Zhang Limei , Song Yan , Zhang Junfei , Tan Zhuomin , Jia Yinnong , Qing Chen
Published: December 2022

Background: EPS8L1, an analog of epidermal growth factor receptor
pathway substrate 8 (Eps8), was screened out in our previous work from
clinical samples of patients with ovarian cancer. Our studies also
indicated that EPS8L1 might involve in various biological activities. In
this study, we further investigated the effect and mechanism of EPS8L1
on the migration and metastasis of ovarian cancer. Methods: SKOV-3 cells
with EPS8L1 overexpression and knockdown were established to perform in
vitro scratch healing, transwell assay and actin-staining studies.
Ovarian cancer mice with lung metastasis was established. Bioinformatics
assay, qRT-PCR and Western blot were conducted to identify correlated
proteins. Also, the Rac1 activity and the expression of MAPK
pathway-related proteins were evaluated. Result: The knockdown of EPS8L1
inhibited the cellular migration in vitro and reduced tumors
colonization in vivo. Actin-staining and ELISA experiment suggested that
EPS8L1 regulated actin formation and cytoskeleton remodeling. Besides,
mRNA and protein expression confirmed that EPS8L1 regulated the
downstream molecule T-cell lymphoma invasion and metastasis 2 (TIAM2)
and stimulated the activation of Rac1. Also, the phosphorylation levels
of P38, Erk and Jnk in MAPK pathway decreased after EPS8L1 knockdown.
Conclusion: The upregulation of EPS8L1 could promote migration and
metastasis of ovarian cancer cells by regulating cytoskeleton
remodeling. The mechanism underlying might be EPS8L1 regulates TIAM2 to
induce Rac-GDP to Rac-GTP and then activates the downstream MAPK
pathway. As a regulatory gene in cell migration and metastasis, EPS8L1
probably provide a new therapeutic target for ovarian cancer treatment.
Reduced tropical climate land area under global warming
Authors: Adam Ori , Liberty-Levi Noga , Byrne Michael , Birner Thomas
Published: December 2022

Regions along the edges of the tropics host vast populations and
ecosystems which are sensitive to climate change. Here we examine the
extent of tropical climate land areas in the ERA5 and MERRA-2 reanalyses
in high-emission scenarios of 45 models participating in phases 5 and 6
of the Coupled Model Intercomparison Project (CMIP5/6). Based on the
definition of tropical climate land areas as regions where the diurnal
temperature range exceeds the seasonal temperature range, we find a net
reduction of tropical land area with global warming. This change is
primarily due to an increased seasonal temperature range, driven by
enhanced summer warming. The reduction in tropical land area is
consistent with the expansion of the subtropical descending zones and
with the expansion of drylands with global warming. However, the
particular contributions of dynamic and thermodynamic processes are not
clear.
Fully coupled photochemistry of the deuterated ionosphere of Mars and its effects on escape of H and D
Authors: Cangi Eryn , Chaffin Michael Scott , Yelle Roger , Gregory Bethan Sarah , Deighan Justin
Published: December 2022

Although deuterium (D) on Mars has received substantial attention, the
deuterated ionosphere remains relatively unstudied. This means that we
also know very little about non-thermal D escape from Mars, since it is
primarily driven by excess energy imparted to atoms produced in
ion-neutral reactions. Most D escape from Mars is expected to be
non-thermal, highlighting a gap in our understanding of water loss from
Mars. In this work, we set out to fill this knowledge gap. To accomplish
our goals, we use an upgraded 1D photochemical model that fully couples
ions and neutrals and does not assume photochemical equilibrium. To our
knowledge, such a model has not been applied to Mars previously. We
model the atmosphere during solar minimum, mean, and maximum, and find
that the deuterated ionosphere behaves similarly to the H-bearing
ionosphere, but that non-thermal escape on the order of 8000-9000
cm-2s-1 dominates atomic D loss under all solar conditions. The total
fractionation factor, f, is 0.04–0.07, and integrated water loss is
147–158 m GEL. This is still less than geomorphological estimates.
Deuterated ions at Mars are likely difficult to measure with current
techniques due to low densities and mass degeneracies with more abundant
H ions. Future missions wishing to measure the deuterated ionosphere in
situ will need to develop innovative techniques to do so.
Five Centuries of Groundwater Elevations Provide Evidence of Shifting Climate Drivers and Human Influences on Water Resources in North Central Florida
Authors: Larson Evan Reed , Mirti Tom , Wilding Thomas , Underwood Chris A
Published: December 2022

Groundwater depletion is a concern around the world with implications
for food security, ecological resilience, and human conflict. Long-term
perspectives provided by tree ring-based reconstructions can improve
understanding of factors driving variability in groundwater elevations,
but such reconstructions are rare to date. Here, we report a set of new
546-year tree-ring chronologies developed from living and remnant
longleaf pine (Pinus palustris) trees that, when combined with existing
bald cypress (Taxodium distichum) tree-ring chronologies, were used to
create a set of nested reconstructions of mean annual groundwater
elevation for North Central Florida that together explain 63% of the
variance in instrumental measurements and span 1498–2015. Split
calibration confirms the skill of the reconstructions, but coefficient
of efficiency metrics and significant autocorrelation in the regression
residuals indicate a weakening relationship between tree growth and
groundwater elevation over recent decades. Comparison to data from a
nearby groundwater well suggests extraction of groundwater is likely
contributing to this weakening signal. Periodicity within the
reconstruction and comparison with global sea surface temperatures
highlight the role of El Niño-Southern Oscillation (ENSO) in driving
groundwater elevations, but the strength of this role varies
substantially over time. Atlantic and Pacific sea surface temperatures
modulate ENSO influences, and comparisons to multiple proxy-based
reconstructions indicate an inconsistent and weaker influence of ENSO
prior to the 1800s. Our results highlight the dynamic influence of
ocean-atmospheric phenomena on groundwater resources in North Central
Florida and build on instrumental records to better depict the long-term
range of groundwater elevations.
Topography of the Vérvár and Otok estate in the Late Middle Ages
Authors: Plantosar Petra
Published: December 2022

The paper explains the distribution, based on sources and historiographical works, of settlements on the Vérvár and Otok estate in the ​​Vukovo County in Hungarian-Croatian Kingdom in the Late Middle Ages. The central part of the paper is the analysis of medieval documents with lists of settlements from 1437, 1446 and 1476. A brief overview of the ownership of the estate was made and the issue of the Selna estate becoming property of the Otok estate was presented. According to the lists of settlements and the years stated in them, geographical maps of the estate were made.
New women in a new state
Authors: Feldman Andrea
Published: December 2022

This paper intends to explain not only the origins of the modern woman in a changing political and social environment in a newly established state after First World War, but also the development of ideas formulated by women in their intellectual endeavors, through their influence and criticism, and their hopes and expectations of the new state. It focuses on Croat and South Slavic spaces in the process of unification of the State of Serbs, Croats and Slovenes in 1918 (called the Kingdom of SHS, Kingdom of Yugoslavia from 1929). This period saw the unprecedented involvement of women in political and public life with the aim of achieving political and legal equality. Examining the complex structural changes that took place amidst great economic, social, and political commotion, the paper encompasses the personalities and ideas that challenged the established understanding of the status of women and analyses the ways and forms of some of their social and public actions. The most important among them was Zovka Kveder Demetrović, a journalist and editor of a prominent women’s magazine Ženski svijet/Jugoslavenska žena [Women’s World/The Yugoslav Woman] whose advocacy of women’s issues is the focus of this paper. It informs the reader on new possibilities of understanding the intellectual and political contribution of women, and identifies the most important, if generally unknown, women authors from the region whose work contributed to the general advancement of women’s issues in the aftermath of First World War.
Milan Sunko
Authors: Heimer Željko
Published: December 2022

Milan Sunko (Zidani Most, 5 December 1860 – Zagreb, 9 March 1891) was a heraldic artist, numismatist, and collector, who studied and started his carrer in Vienna working with the most renowned heraldists of the “classical” Austrian heraldic period. He moved to Zagreb where he made number of well received paintings and graphics and was supported by the intelectual elite of the fastly developing city. His brief spectacular carrier was abruptly ended by laryngeal tuberculosis, and he died in his 31st year. His works are preserved in several museums and galleries in Zagreb, and his heraldic lithographs and ex libris bookplates are remembered in specialized bibliography. However, the Croatian heraldic historiography has forgotten all about him and this paper attempts to remedy this. After the establishment of the Brotherhood of Croatian Dragon Society – one of its founders being Emilij Laszowski, notable Croatian heraldist; it took upon a project to preserve Sunko’s grave, exhuming his remains and providing a modest but dignified grave for him at the Zagreb cemetary in 1910. To achieve that, the Draconian Society raised funds in an international action, activating his foreign friends and fans, documenting the project in respectable heraldic periodicals.
What Varaždin high school students know and think about fascism and anti-fascism?
Authors: Huzjan Vladimir
Published: December 2022

In this paper, the author presents the results of a survey conducted electronically from the beginning of March to the end of May 2021 among students of nine high schools in Varaždin on their knowledge and attitudes about fascism and anti-fascism. The survey consisted of 20 questions, and the answers were given by 356 students. This paper does not bring critiques or suggestions of the history curriculum for high schools, but presents some of its results. Special attention was paid to the events marking the 80th anniversary of the persecution of Jews in Varaždin (1941-2021), which were held during July 2021.
Political circumstances and security situation in Western Slavonia on the eve of the Greater-Serbian Aggression in 1991
Authors: Martinić Jerčić Natko
Published: December 2022

Based on archival sources and relevant literature, this paper portrays political circumstances and security situation in Western Slavonia from 1989, that is, from collapse of the communist systems in Europe and destabilisation of Yugoslavia by the political leadership of the Socialist Republic of Serbia, up until August 1991 when the overt Greater-Serbian Aggression started in Western Slavonia. Democratic processes in Europe also seized western Yugoslav republics, Slovenia and Croatia. These republics advocated either the restructure of Yugoslavia as a confederal state, or their independence in case that the political agreement with other republics about common state system was not feasible. Conversely, Serbian political leadership’s goal, supported by pro-Serbian oriented leadership of the federal Yugoslav People’s Army, was to impose Yugoslavia as a centralized state under the domination of Serbs, as the most numerous Yugoslav nation. After this policy failed, Serbian leadership attempted to create Greater Serbia which would comprise all territories which Serbian leadership considered as historically and ethnically a Serbian territory. Among others, that also included Western Slavonia where a certain part of population were ethnic Serbs. Part of these Serbs, as well as ethnic Serbs in certain other parts of Croatia, supported by Belgrade, gradually commenced rebellion against the Croatian authorities. Insurgency was led by representatives of Serbian Democratic Party whose centre was in town Knin. In the first phase of destabilisation the emphasis was on the thesis that the Serbs were endangered in Western Slavonia, in order to radicalize as many as possible, which was successfully implemented, and finally led to terrorist actions culminating with the open aggression in Western Slavonia.
Secure cloud internet of vehicles based on blockchain and data transmission scheme of map/reduce
Authors: Lin Hua-Yi
Published: December 2022

Over the past few years, because of the popularity of the Internet of vehicles and cloud computing, the exchange of group information between vehicles is no longer out of reach. Through WiFi/5G wireless communication protocol, vehicles can instantly deliver traffic conditions and accidents to the back end or group vehicles traveling together, which can reduce traffic congestion and accidents. In addition, vehicles transmit real-time road conditions to the cloud vehicle management center, which can also share real-time road conditions and improve the road efficiency for pedestrians and drivers. However, the transmission of information in an open environment raises the issue of personal information security. Most of the security mechanisms provided by the existing Internet of vehicles require centralized authentication servers, which increase the burden of certificate management and computing. Moreover, the road side unit as a decentralized authentication center may be open to hacking or modification, but due to personal privacy and security concerns, vehicle-to-vehicle is not willing to share information with each other. Therefore, this study is conducted through blockchain to ensure the security of vehicle-based information transmission. Moreover, the elliptic curve Diffie?Hellman (ECDH) key exchange protocol and a secure conference key mechanism with direct user confirmation combined with the back-end cloud platform Map/Reduce is proposed to ensure the identities of Mappers and Reducers that participate in the cloud operation, avoid malicious participants to modify the transmission information, so as to achieve secure Map/Reduce operations, and improves vehicle and passenger traffic safety.
Racial-ethnic differences in associations between traumatic childhood experiences and both metabolic syndrome prevalence and type 2 diabetes mellitus risk among a cohort of US women
Authors: Gaston Symielle A. , Riley Nyree M. , G. Parks Christine , Woo Jennifer M.P. , Sandler Dale P. , Jackson Chandra L.
Published: December 2022

  

Objective: Childhood adversity has been associated with metabolic syndrome (MetS) and type 2 diabetes risk in adulthood. However, studies have yet to investigate traumatic childhood experiences (TCEs) beyond abuse and neglect (e.g., natural disaster) while considering potential racial-ethnic differences. 

Research Design and Methods: To investigate race-ethnicity as a potential modifier of the TCEs-MetS-type 2 diabetes association, we used prospectively collected data from 42,173 eligible non-Hispanic White (NHW [88%]), Black/African American (BAA [7%]), and Hispanic/Latina (4%) Sister Study participants (aged 35-74 years) enrolled from 2003-2009. A modified Brief Betrayal Trauma Survey captured TCEs. At least three prevalent metabolic abnormalities defined MetS, and self-report of a new diagnosis during the study period defined type 2 diabetes. We used adjusted Cox Proportional Hazards regression to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) for type 2 diabetes over a mean ± SD follow-up of 11.1 ± 2.7 years, overall and by race-ethnicity. We also tested for modification and mediation by MetS. 

Results: Incident cases of type 2 diabetes were reported (2,479 among NHWs, 461 among BAAs, and 281 among Latinas). Reporting any TCEs (50% among NHWs, 53% among BAAs, and 51% among Latinas) was associated with a 13% higher type 2 diabetes risk (HR=1.13 [95% CI: 1.04-1.22]). Associations were strongest among Latinas (HR=1.64 [1.21-2.22] vs. HRs=1.09 for BAAs and NHWs). MetS was not a modifier but mediated (indirect effect: HR=1.01 [1.00-1.01], p=0.02) the overall association. 

Conclusions: TCE-type 2 diabetes associations varied by race-ethnicity and were partially explained by MetS.
Concomitant use of sulfonylureas and beta-blockers and the risk of severe hypoglycemia among patients with type 2 diabetes: a population-based cohort study
Authors: Dimakos Jenny , Cui Ying , Platt Robert W , Renoux Christel , Filion Kristian B. , Douros Antonios
Published: December 2022

  

Background: The hypoglycemic potential of beta-blockers among users of sulfonylureas, drugs that strongly increase the risk of this potentially fatal adverse effect, is not well understood. Our population-based cohort study assessed the potential association between concomitant use of sulfonylureas and beta-blockers versus use of sulfonylureas alone and the risk of severe hypoglycemia.

Methods: Using the UK's Clinical Practice Research Datalink Aurum, we included patients initiating sulfonylureas between 1998 and 2020, excluding those with beta-blocker use in the past 6 months. Time-dependent Cox models estimated hazard ratios (HRs) with 95% confidence intervals (CIs) of severe hypoglycemia (hospitalization with or death due to hypoglycemia; ICD-10 codes: E16.0, E16.1, E16.2) associated with current concomitant use of sulfonylureas and beta-blockers compared to current sulfonylurea use alone, adjusted for baseline confounders. We also compared current concomitant use of sulfonylureas and non-cardioselective versus cardioselective beta-blockers.

Results: Our cohort included 252,866 initiators of sulfonylureas (mean age 61.3 years, 43% female). Median follow-up was 7.9 years. The crude incidence rate of severe hypoglycemia was 7.8 per 1000/year. Concomitant use of sulfonylureas and beta-blockers was associated with an increased risk of severe hypoglycemia compared to sulfonylurea use alone (HR, 1.53; 95% CI, 1.42-1.65). There was no difference in the risk between concomitant use of sulfonylureas and non-cardioselective beta-blockers and concomitant use of sulfonylureas and cardioselective beta-blockers (HR, 0.95; 95% CI, 0.74-1.24).

Conclusion: Beta-blockers could further increase the risk of severe hypoglycemia when used concurrently with sulfonylureas. Beta-blocker cardioselectivity did not appear to play a major role in this regard.

 
The anti-narcolepsy drug modafinil reverses hypoglycemia unawareness and normalizes glucose sensing of orexin neurons in male mice.
Authors: Patel Vishwendra , Sarkar Pallabi , Siegel Dashiel M. , Teegala Suraj B. , Hirschberg Pamela R. , Wajid Hamad , Itani Omar , Routh Vanessa H.
Published: December 2022

  

Perifornical hypothalamus (PFH) orexin glucose-inhibited (GI) neurons that facilitate arousal have been implicated in hypoglycemia awareness. Mice lacking orexin exhibit narcolepsy and orexin mediates the effect of the anti-narcolepsy drug, modafinil. Thus, hypoglycemia awareness may require a certain level of arousal for awareness of the sympathetic symptoms of hypoglycemia (e.g., tremors, anxiety). Recurrent hypoglycemia (RH) causes hypoglycemia unawareness. We hypothesize that RH impairs the glucose sensitivity of PFH orexin-GI neurons and that modafinil normalizes glucose sensitivity of these neurons and restores hypoglycemia awareness after RH. Using patch clamp recording, we found that RH enhanced glucose inhibition of PFH orexin-GI neurons from male mice, thereby blunting activation of these neurons in low glucose. We then used a modified conditioned place preference (CPP) behavioral test to demonstrate that modafinil reversed hypoglycemia unawareness in male mice after RH. Similarly, modafinil restored normal glucose sensitivity to PFH orexin-GI neurons. We conclude that impaired glucose sensitivity of PFH orexin-GI neurons plays a role in hypoglycemia unawareness and that normalizing their glucose sensitivity after RH is associated with restoration of hypoglycemia awareness. This suggests that the glucose sensitivity of PFH orexin-GI neurons is a therapeutic target for preventing hypoglycemia unawareness.
Kto wyrzuca pieniądze przez okno – czyli potlacz w archeologii
Authors: Gralak Tomasz
Published: December 2022

The article analyses various archaeologically perceptible methods of withdrawing goods from circulation. This phenomenon is known as potlatch. Its social and economic context was considered on the basis of various prehistoric cultures in Central Europe. It is pointed out that this is a phenomenon typical of a peripheral economy and a hierarchical social structure.
Ovruch slate spindle whorls in the Czech Lands
Authors: Kouřil Pavel , Přichystal Antonín
Published: December 2022

The article discusses the state of knowledge and the significance of a special group of early medieval material culture artefacts – namely, spindle whorls made of Ovruch pyrophyllite slate originating from the territory of present-day Ukraine. Thousands of these artefacts, interesting not only for their specific, usually reddish color, but also for their professional standardized design, were made between the 10th and 13th c. Their occurrence in the Czech lands is very limited, however: only 13 specimens are presently known. In Bohemia, they have been discovered only in Prague, which was their target destination. In Moravia and Czech Silesia, they are known from five sites: with a single exception (a cemetery), they are important supra-regional and local fortified centers. Non-destructive analyses carried out have shown that all detected spindle whorls can be considered originals. An analysis of the archaeological contexts showed that the earliest occurrence of these imports can be dated as far back as the second half of the 10th century. However, most of them probably belong to the 11th century, and some, exceptionally, even to the 12th century. Given their low number, we assume that this most probably was not a regular item in long-distance trade.
Video Pembelajaran Berbantuan Aplikasi Video Scribe Berbasis Pembelajaran Tematik Untuk Topik Keseimbangan Ekosistem Bagi Siswa Kelas V
Authors: Ilyas Muhammad Ilyas , Suarjana I Made , Yudiana Kadek
Published: December 2022

Kegiatan belajar mengajar di sekolah sudah cukup baik, namun siswa masih kurang tertarik dengan media yang digunakan oleh guru, hal ini disebabkan karena kurangnya media pembelajaran yang dikembangkan oleh guru apalagi pada saat ini kegiatan belajar mengajar dilakukan secara daring yang membuat pembelajaran semakin tidak efektif. Penelitian ini bertujuan untuk mengembangkan video pembelajaran berbantuan aplikasi video scribe berbasis pembelajaran tematik untuk topik kesimbangan ekosistem bagi siswa kelas V. Model pengembangan yang digunakan dalam penelitian ini adalah model ADDIE, namun pada tahap implementasi dan evaluasi tidak dilaksanakankarena adanya kerterbatasan dari segi waktu, finansial, tenaga dan sumber daya. Subjek penelitian ini adalah dua dosen sebagai ahli, dua orang guru dan siswa (uji kelompok kecil). Metode yang digunakan dalam penelitian ini yaitu kuesioner. Data yang diperoleh dilakukan uji validitas yang dihitung menggunakan rumus aiken’s,  uji respon guru dan siswa menggunakan rumus deskriptif presentase.  Hasil analisis yang diperoleh hasil uji ahli materi soal diperoleh 0,875 dengan kualifikasi sangat valid, hasil uji ahli media diperoleh 0,886 dengan kualifikasi sangat valid, hasil respon praktisi diperoleh persentase 97% dengan kualifikasi sangat baik dan hasil respon siswa diperoleh persentase 99% dengan kualifikasi sangat baik. Hal ini menunjukkan bahwa media yang dikembangkan layak digunakan dalam pembelajaran.
ASSESSMENT OF GROWTH RATES OF ACIPENSER NUDIVENTRIS THORN JUVENILES GROWN IN THE UNC RAS AQUATIC COMPLEX
Authors:   Federal Research Center Southern Scientific Center of the Russian Academy of Sciences, Rostov-on-Don, Russian Federation, V.A. Sergeeva , D.S. Tazhbaeva , M.V. Kovalenko ,   Don State Technical University, Rostov-on-Don, Russian Federation
Published: December 2022

The article describes the assessment of the physiological state of the juvenile thorn, grown in the aquatic complex of the YUNC RAS. The assessment of fish-breeding and biological indicators is carried out. The necessity of growing this species in closed water supply installations is substantiated.
TECHNOLOGY FOR THE CREATION OF GENETICALLY MODIFIED ORGANISMS
Authors:   Don State Technical University, Rostov-on-Don, Russian Federation, M.A. Grigoryan , M.A. Kutyga , L.V. Milyaeva
Published: December 2022

The article provides an overview of the process of creating GMOs. The safety and relevance of the presented technology is also considered. The connection of genetic engineering with GMOs is described. The stages of creation of organisms with genetic modification are presented.
APPLICATIONS ENVIROMENTAL DNA (eDNA) IN AQUACULTURE
Authors:   Azov-Black Sea Branch of “VNIRO” (“AzNIIRKH”), Rostov-on-Don, Russian Federation, I.V. Golovinov , A.V. Vorobeva , A.Sh. Alimova , V.N. Gaidamachenko , N.A. Nebesikhina ,   Southern Federal University, The Academy of Biology and Biotechnology named after D. I. Ivanovsky, Rostov-on-Don, Russian Federation,   Don State Technical University, Rostov-on-Don, Russian Federation
Published: December 2022

Early detection and control of fish diseases is critical for aquaculture. Traditional monitoring methods are time consuming and often ineffective. Environmental DNA (eDNA) can be used to monitor waterborne infections in fish. The present study examined the application of environmental DNA to the monitoring of infectious diseases in fish in aquaculture. Literature data on the use of eDNA in the diagnosis of pathogens using various methods of molecular biology are presented.
THE USE OF DRUGS TO COMBAT SAPROLEGNIOSIS AND THEIR EFFECT ON THE RESULT OF HATCHING OF STURGEON LARVAE
Authors:   All-Russian Research Institute of Integrated Fish Farming - a branch of the Federal State Budgetary Scientific Institution ", P.S. Iliushina ,   Federal Research Center for Animal Husbandry - VIZH named after Academician L.K. Ernst",   Vorovskogo, Russian Federation, A.V. Brigida
Published: December 2022

Based on scientific research, the article presents the main morphometric indicators of sterlet grown in closed water supply installations under certain conditions: temperature, oxygen and pH modes. The article describes the behavior of these sturgeon fish in favorable and unfavorable conditions. The analysis of scientific articles on this topic was carried out and the results of the study were presented.
MONOGENEA (PLATYHELMINTHES) INVASION IN CYPRINID FISH IN THE DON RIVER DELTA AND THE EASTERN PART OF THE TAGANROG BAY UNDER PRESENT CONDITIONS
Authors:   The Southern Scientific Centre of the Russian Academy of Sciences, Rostov-on-Don, Russian Federation, А.V. Kazarnikova , Y.V. Stepanova
Published: December 2022

The data on monogenean fauna of cyprinid fish (prussian carp, Carassius gibelio, bream, Abramis brama, common carp, Cyprinus carpio, and ram, Rutilus rutilus) in the Don River delta and the eastern part of the Taganrog Bay are presented. An annotated list of monogenean species of these fishes, which currently includes 24 species from 3 families (Dactylogyridae, Gyrodactylidae, Diplozoidae) is given. Representatives of the families Dactylogyridae dominated in terms of the number of species (14 species). The data on monogenean invasion of cyprinid fish species under present ecological conditions are analyzed. Epizootically significant for fish health were Dactylogyrus extensus, D. vastator, Gyrodactylus sprostonae, G. medius and Diplozoon paradoxum.
COELENTERATES AS AN OBJECT OF AQUACULTURE AND PROSPECTS FOR THEIR PRACTICAL USE
Authors:   Don State Technical University, Rostov-on-Don, Russian Federation, A.R. Neidorf , P.A. Zhukova
Published: December 2022

The article considers the features of evolution, systematics, nutrition and reproduction of coelenterates, determining their role in aquatic ecosystems. The features of the position in trophic chains and the significance for the topological organization of water cenosis are considered. Based on the ecological significance, possible ways of practical use are identified and the main problems of artificial breeding of coelenterates are outlined.
Determinan Konsentrasi Spasial dan Daya Saing Industri Manufaktur Besar dan Sedang Jabodetabek
Authors: Muhammad Ilham , Emalia Zulfa
Published: December 2022

The aim of this research is to analyze if the large-medium sized manufacture industries in the Jabodetabek are spatially concentrated and to analyze how spatial concentration is affected by the regional and industry specific variabels and the competitiveness strength of said industries. Using Hoover- Balassa Index (HBI) to gauge the spatial concentration strength caused by agglomeration as dependent variable, Industry Size, Competitiveness Index using output-based Location Quotient (LQ), and City/District Minimum Wage (UMK) as independent variables. Using panel data analysis and Geography Information System (GIS) to see where the industries are concentrated spatially in relation to others. It is found that the large and medium-sized manufacture industries in Jabodetabek are indeed spatially concentrated. Granger Causality Test indicates there is only one-way positive causality and that is industry competitiveness to industry spatial concentration. The independent Variable that affect spatial concentration of large and medium-sized industries in Jabodetabek positively are Industry Size, and Competitiveness Index.
Faktor-Faktor yang Mempengaruhi Pengeluaran Konsumsi Kesehatan Rumah Tangga Di Kelurahan Penengahan Raya
Authors: Ayu Lestari Mega , Emalia Zulfa
Published: December 2022

This study aims to identify the average and percentage of household health consumption expenditure and factors that affect household health consumption expenditure in Penengahan Raya Village The City of Bandar Lampung. To indentify the average and percentage of household health consumption expenditure were done statistic descriptively, while the analysis method used to identify the influence of these factors is multiple regression with the method of Ordinary Least Square Method (OLS). The research results showed the average household health consumption expenditure is Rp 335,783 or 13% of all household consumption expenditures and the estimated results show that individually and collectively, the household income,  the age of the head of the family, the number of family members, the level of education of the head of the family, and the participation of the family in health insurance have a significant positive effect on household health consumption expenditures.
Perbandingan Efisiensi Analisis Teknikal, SMA dan EMA dalam Mengestimasi Harga Saham
Authors: Abid Shabrina  , Hasnawati Sri
Published: December 2022

The development of the times also encourages economic growth in every country. With more income, people have a desire to invest their excess income for investment activities. The investment made aims to get a profit or return. Stock return is the result (profit or loss) obtained from a stock investment. This of course requires technical analysis of which there are Simple Moving Average, and Exponential Moving Average. This study aims to compare the two analyzes and which one is more efficient in manufacturing companies on the IDX in 2021. Based on the results of the study, it is known that the Exponential Moving Average with a period of 30 days is an efficient stock price estimation analysis in estimating stock prices from the 4 sub-sectors contained in the mining sector on the Indonesia Stock Exchange in 2021. The Simple Moving Average becomes an analysis of stock price estimates that are less efficient in estimating the share price of the mining sector on the Indonesia Stock Exchange in 2021. The study also found that in the EMA method, the longer the analysis period used, the the better the prediction results with the smaller the variance description value indicator.
Analisis Permintaan Jasa Transportasi Funotrans Di Kota Bandar Lampung
Authors: Mutiara Hati Sesunan Karina , Ratih Arivina
Published: December 2022

This study aims to determine and analyze respondents' income variables, prices for FunoTrans services, prices for other services, and user satisfaction with the number of requests for FunoTrans transportation services in Bandar Lampung City. The research uses descriptive quantitative methods which are classified as survey research, namely research that takes samples from one population by using a questionnaire. The research method uses multiple linear regression analysis. The results of this study include; the price of online transportation services for motorbikes and cars using the FunoTrans application has a positive and significant effect; the price of other online transportation services for motorcycles and cars has a positive and significant effect; respondent's income has no significant effect; and user satisfaction have a significant effect on the demand for online transportation services in the FunoTrans application.
Analisis Kepuasan Masyarakat Pada Layanan SKTM di Kantor Desa Bangunrejo Kecamatan Semaka Kabupaten Tanggamus
Authors: Bunga Sartika , Wahyudi Heru
Published: December 2022

The purpose of this study was to determine the level of community satisfaction on the quality of services carried out by the village apparatus of Bangunrejo sub-district, Semaka district, Tanggamus district in providing services for making SKTM (Certificate of Disability). The research method used in this research is descriptive qualitative. Qualitative descriptive research is research that aims to describe and describe the conditions that occur in the field. The research technique uses primary data obtained from distributing questionnaires to the people of Bangunrejo village who have taken care of the SKTM for the last 2 years (2020-2021), as many as 369 residents. The theory used is Hardiansyah (2011) which states that community satisfaction is formed because of good service quality where the service is in accordance with community expectations. Good service quality consists of 5 dimensions, namely: responsiveness, reliability, attention, assurance, and physical ability. The results of the respondents' responses to the highest community satisfaction came from the dimensions of reliability and attention. While the dimension that has the lowest level of satisfaction comes from the dimension of physical ability.
Pengaruh SUN, SBSN, Inflasi, Nilai Tukar, Pertumbuhan Ekonomi Terhadap Defisit APBN Di Indonesia Periode 2009Q1-2021Q4
Authors: Damayanti Nabilah Putri , Marselina
Published: December 2022

Tⱨis study aims to determine the effect of SUN, SBSN, Inflation, Excⱨange Rate, Economic Growtⱨ on the APBN deficit in Indonesia for the 2009Q1-2021Q4 period. This study uses tⱨe Error Correction Model (ECM) as the method of analysis. By using quarterly time series data from 2009Q1 – 2021Q4. Tⱨe results in this study indicate tⱨat the SUN variable has a negative and significant effect on the APBN deficit in Indonesia. SBSN sⱨows a positive and insignificant relationsⱨip to the APBN deficit in Indonesia. Inflation is positively and not significantly related to the APBN deficit in Indonesia. Tⱨe excⱨange rate is positively and significantly related to the APBN deficit in Indonesia. Economic growtⱨ has a negative and significant effect on the APBN deficit in Indonesia.
Prototipe Dashboard Aplikasi POSTASY Berbasis Website Menggunakan Metode Pureshare untuk Meningkatkan Kemudahan Layanan Posyandu
Authors: Maghfira Salma , Sagirani Tri , Amelia Tan
Published: December 2022

Abstract. Dashboard Prototype of Website-Based Postasy Application Using the Pureshare Method to Improve the Convenience of Posyandu Services.Integrated Service Post (Posyandu) is a form of community-based health service. Recording of data in a Posyandu is the main activity. To support the main activities, Posyandu has a Postasy website that can display information, maintain data and manage every detail that will be used. The evaluation results showed that the website has deficiencies in the value of memorability and satisfaction, and the dashboard display is inadequate. The solution offered to redesign the dashboard using the pureshare method and the double diamond model as a stage in building a prototype. The final test of the prototype results using the UXT usability test tool and a questionnaire. The test results through the distribution of questionnaires are 87.3% in memorability and 84.8% in satisfaction. The results of testing using UXT obtained 100%, which means that the design is excellent, can be accepted by respondents, and becomes a recommendation.Keywords: Posyandu, redesign, usability testing
Abstrak. Pos Pelayanan Terpadu (Posyandu) adalah suatu bentuk layanan kesehatan berbasis masyarakat. Pencatatan dan perekapan data di sebuah Posyandu merupakan kegiatan utama yang dilakukan. Untuk mendukung kegiatan utama Posyandu memiliki website Postasy yang dapat menampilkan informasi yang dibutuhkan, memelihara data dan mengelola setiap detail yang akan digunakan. Berdasarkan hasil wawancara terdapat beberapa keluhan terhadap tampilan website Postasy. Dari hasil evaluasi didapatkan data bahwa website memiliki kekurangan pada nilai memorability dan satisfaction dan juga tampilan dashboard yang kurang memadai. Solusi yang ditawarkan adalah mendesain ulang dashboard menggunakan metode pureshare, dan model double diamond sebagautahapan dalam membangun prototype. Pengujian akhir terhadap hasil prototipe dilakukan dengan menggunakan uji usability tools UXT dan kuesioner. Hasil pengujian melalui penyebaran kuesioner diperoleh hasil 87,3% untuk memorability dan 84,8% untuk satisfaction. Hasil pengujian menggunakan UXT diperoleh hasil 100% yang artinya dapat disimpulkan bahwa desain sangat baik, dan dapat diterima oleh responden sehingga menjadi rekomendasi pengguna.Kata Kunci: Posyandu, desain ulang, usability testing
Analisis Usability Menggunakan Metode Heuristic Evaluation dan Web Usability Evaluation Tool pada Website ACC Career
Authors: Dewi Findra Kartika Sari , Yonathan Dri Handarkho  , Felcia Veronica Prasetyo
Published: December 2022

Abstract. ACC Career website is a website from PT. Astra Credit Companies which aims for work applications. The website has been around for a long time but has never been updated. Recently, ACC has been revamping the website. Before the new website is launched, a usability evaluation is carried out using the heuristic evaluation and WEBUSE methods which aims to determine the website usability assessment for both the old and the new user interface. Usability is said to be good if users find it easy, happy and satisfied using the system. The heuristic evaluation method brings out problems in the system and recommendations for improvement from the evaluator. The Web Usability Evaluation Tool brings out usability levels based on the assessment of the questionnaire respondents. From the old website, the evaluator found 48 problems and the usability level obtained from the respondents' answers were Good for all categories. From the new website, the evaluators found 42 issues and the usability level was evenly divided between Good and Excellent.Keywords: Revamp, Website, Usability, Heuristic Evaluation, WEBUSE.
Abstrak. Website ACC Career merupakan website dari PT. Astra Credit Companies (ACC) yang bertujuan untuk pengaplikasian pekerjaan. Website ini sudah ada sejak lama tetapi belum pernah ada pembaharuan. Baru-baru ini ACC sedang melakukan pengembangan ulang (revamp) website tersebut. Sebelum produk baru diluncurkan, diadakan evaluasi usability menggunakan metode Heuristic Evaluation dan WEBUSE yang bertujuan untuk mengetahui penilaian usability website baik untuk tampilan lama maupun tampilan yang sedang dikembangkan. Usability dikatakan baik jika pengguna mudah, senang, dan puas menggunakan sistem. Metode Heuristic Evaluation menghasilkan permasalahan yang ada pada sistem dan rekomendasi perbaikan dari evaluator. Metode Webuse menghasilkan tingkat usability berdasarkan penilaian responden kuisioner. Pada tampilan lama, evaluator menemukan 48 permasalahan dan level usability yang didapat dari jawaban responden adalah Good untuk seluruh kategori. Pada tampilan baru, evaluator menemukan 42 permasalahan dan level usability terbagi rata antara Good dan Excellent.Kata Kunci: Revamp, Website, Usability, Heuristic Evaluation, WEBUSE.
Hubungan Motivasi Belajar Terhadap Hasil Belajar Siswa Pada Mata Pelajaran Administrasi Infrastruktur Jaringan Kelas Xll Di SMK Negeri 6 Padang
Authors: Ilhami Fahmi , Mulyono Heri , Ade Darman Regina
Published: December 2022

This study aims to determine whether there is a positive and significant contribution between learning motivation and student learning outcomes in the class XII Network Infrastructure Administration subject at SMK Negeri 6 Padang. This type of research is quantitative using correlational research methods. The population in this study were class XII students of the Department of Computer and Network Engineering at SMK Negeri 6 Padang. The sampling technique used is Simple Random Sampling, which was selected as a sample in this study amounted to 41 students. Based on the results of the study, the coefficient of the contribution of learning motivation and learning outcomes was 20.88%. From the data analysis test, it is known that the data are normal and linear. The test results at a significance level of 0.05 (95% confidence level) obtained the value of tcount = 3.210 and ttable = 2.02 because tcount (3.210) > ttable (2.02). Thus  is rejected and  is accepted, which means that there is a positive and significant contribution between learning motivation and student learning outcomes in the subject of Network Infrastructure Administration (AIJ) class XII at SMK Negeri 6 Padang.  Keywords: contribution, motivation, learning outcomes
UPAYA PENINGKATAN HASIL BELAJAR MATA PELAJARAN PEKERJAAN DASAR TEKNIK MESIN DENGAN MODEL PEMBELAJARAN KOOPERATIF TIPE JIGSAW DI SMK NEGERI 1 SUMATERA BARAT
Authors: Pratama Fikri Alvion , Erizon Nelvi , Wulansari Rizky Ema
Published: December 2022

Era globalisasi membuat pemerintah perlu berbagai dorongan sumber daya manusia untuk meningkatkan kualitas pendidikan. Pembelajaran yang berlangsung pada kelas menjadi kunci utama keberhasilan pendidikan, sehingga pembelajaran yang di implementasikan pendidik menjadi sangat penting. Model pembelajaran yang dipergunakan oleh pengajar masih belum bervariasi hingga peserta didik yang ditemukan masih rendah pada nilai belajar, maka hasil belajar pada peserta didik kelas X TP-1 masih banyak yang belum memenuhi nilai KKM. Penelitian dilakukan bertujuan untuk meningkatkan hasil belajar peserta didik pada pembelajaran Pekerjaan Dasar Teknik Mesin (PDTM) memakai model pembelajaraan kooperatif tipe jigsaw di Sekolah Menengah Kejuruan Negeri 1 Sumatera Barat. Metode penelitian yang dipergunakan pada penelitian ialah metode classroom action research. Hasil belajar di siklus I, diperoleh 63,9% peserta didik yang telah memenuhi pada nilai KKM (65,00) dan 36,1% peserta didik yang belum memenuhi nilai KKM. Pada siklus II, presentase belajar yang dihasilkan peserta didik yang telah memenuhi nilai tuntas mencapai 80,6% dan sebesar 19,4% peserta didik belum memenuhi nilai minimum. kesimpulan dari penelitian ini ialah selesainya melakukan penelitian selama 2 siklus, maka diperoleh bahwa pembelajaran kooperatif tipe jigsaw pelajaran Pekerjaan Dasar Teknik Mesin (PDTM) kelas X TP-1 pada SMK Negeri 1 Sumatera Barat dapat mempertinggi hasil belajar peserta didik dengan presentase ketuntasan klasikal hasil belajar sebesar 75%.