bluuebunny/crossref_metadata_2025 huggingface dataset:
E-banking analysis during COVID-19 pandemics
Authors: Kovinić Nikola , Savić Marko , Pavlović Nikola
Published: March 2023

Electronic banking presents a general term used to denote a process allowing legal and physical entities to perform personal and commercial banking transactions by using electronic and telecommunication networks. It covers various jobs such as assets transfers, current account statements, bill payments, the closest ATM locating, attaining the information about financial products and services, loan applications, and some other activities performed with the use of a computer, smartphone, or some other technical devices. The subject of this research study is the analysis of the e-banking usage during COVID-19 pandemics in the Republic of Serbia and Bosnia and Herzegovina. COVID-19 pandemics influenced a great number of transactions to be done online, i.e. by using digital payment options. Furthermore, it affected banks to develop extra benefits for their users, as well as, to promote current e-architecture referring to the possibilities of e-banking use.
Digital assets: A legal approach to the regulation of the new property law institute
Authors: Mirković Predrag
Published: March 2023

Development of a digital technology has transformed the way in which an individual, a social group or community, i.e. a state, interacts in their domains of interest. The application of a digital technology, especially ICT, has caused the need to review whether the existing legislative solutions correspond to such news, or whether it is necessary to change or supplement the legal system of the state with new regulations. One of such issues refers to the creation of new types of assets identified as digital assets or the assets based on the creation of a digital technology. The subject of the research paper is the analysis of the institute of digital property with a special reference to the legislative domain of the way of issuing digital property. In his work, the author affirmed the issue of the importance of the legislative challenge in the standardization of relevant social phenomena and relations in the age of the intensive development and application of a digital technology. The aim of the work was achieved in the domain of the conducted normative analysis of the relevant provisions of the Digital Property Act in the part referring to the legislative approach to standardizing the concept of the digital property institute, as well as the particular issues from the domain of issuing digital property
Normative regulation of electronic administration in Republic of Serbia
Authors: Golić Darko
Published: March 2023

Following the general trend of the technical-technological progress in society, where technology is increasingly important in everyday life, states and public authorities on all continents strive to facilitate the exercise and protection of the rights of their citizens, and to remove bureaucratic barriers that previously existed and were a common accompaniment appearance of the administrative procedure. As an expression of such an aspiration, but also as a necessary consequence of the technical progress, many countries are introducing a system of electronic public administration. Following this trend, our legislator also establishes a system of electronic public administration, with which he tries to facilitate the exercise of citizens' rights, but also to improve the image that citizens have of a public administration, previously known for its sluggishness and inefficiency. The introduction of electronic administration into the domestic legal system, on the other hand, was done without a sufficient preparation, and it was not realized without certain difficulties, both at the normative level as well as at the level of the implementation of various normative solutions. This paper presents the legal regulations, i.e. the normative framework regulating the introduction and functioning of electronic administration in Republic of Serbia.
Jurisdiction for criminal offenses of cybercrime: International and national standards
Authors: Dragojlović Joko
Published: March 2023

Criminal acts of a computer crime are no longer a new social and legal phenomenon. In addition to the execution of criminal acts that fall within the domain of a computer crime, computers have found their application in the execution of the so-called classic criminal acts, giving them a different modus operandi. A spatial distance between the action taken and the resulting consequences during the execution of criminal acts of a computer crime, led to the strengthening of the transnational crime. Initially, the international community tried to intervene in this area, with the idea of regulating the criminal prosecution of the perpetrators of the cross-border criminal acts of a computer crime. However, to date, there has been adopted no normative framework regulating the issue of prosecuting the perpetrators of these criminal acts at the universal level. In this sense, the paper analyzes the existing international standards with regard to the normative arrangement of jurisdiction for the prosecution of perpetrators of transnational computer crimes. In addition, the paper contains a presentation of the normative arrangement of this issue in domestic legislation.
Digital transformation of the Business Registers Agency in the function of the modern digital society
Authors: Vasić Milica , Bulatović Petar
Published: March 2023

Digitalization strongly affects the economy and society as a whole in different dimensions. The process of digitalization of the Business Registers Agency, including the registration procedure of business entities, is one of the priority tasks aimed at increasing efficiency and economy as well as economic prosperity in general. Certainly, there is a prerequisite referring to the existence of digital literacy, which is not an isolated category, but rather a superstructure of earlier forms of literacy. It is undeniable that every innovation arises as a privilege of the higher social classes, which, by inertia, turns into a need of the others. In this paper, it has been analyzed the legislative framework of electronic registration of business entities. Starting from the point of view that economic growth, competitiveness on the market, and socio-economic development represent the nowadays necessity, the authors, through this paper, primarily try to define the achieved progress of the work of the Business Registers Agency (BRA) in registering business entities in the digitalization process. The quintessence of this work is the identification of the availability of digital tools for the registration of economic entities, as well as their quantification and qualification.
Dilemma regarding the scope of projects in the development of key educational competences of pre-school children
Authors: Kravarušić Vesna
Published: March 2023

Conscious education, as a deliberate, planned and organized pedagogical process ensures the acquisition of knowledge, skills and habits in the function of developing learning, expanding and enriching human cognition. At the preschool age, education, through the development of general and special preparations, enables the child to perform life's functions, humanize his nature and adopt and cultivate the foundations of the culture of civilization. The base for the transfer of material and spiritual values of the community is made up of sociocultural systems: symbolization and communication, systems of knowledge from science, technique, technology, work and production, artistic forms of expression, value and ethical attitudes. Through models of daily living, forms of play and learning, the child masters the program of preschool upbringing and education, which should eventually develop their competencies (through learning to learn - for the mother language and another language, mathematical, scientific, technological, digital, social knowledge, cultural awareness and initiative). Research with the aim of improving the projects was carried out using a descriptive method, analysing the content of ten published projects, which identified their characteristics: educational content, types and combinations of implemented activities, used educational methods and specific educational competencies that were supported. The results speak of the use of limited educational contents of only one educational area, weak integration of contents, no changes in the application of the methodical repertoire (compared to the period until 2018) and favouring the development of children's scientific competences.
Applied financial methods on the example of selected REITs from the S&P500
Authors: Cicmil Danica , Đaković Miloš , Jakšić Pavle
Published: March 2023

This paper builds on the existing paper "The financial performance of selected REITs from S & P500" (Cicmil, Đaković, & Inđić, 2022). This paper included four stocks: 1. Public Storage: PSA, 2. Host Hotels & Resorts: HST, 3. Healthpeak Properties: Peak, 4. AIMCO: AIB, and conducted two performance measurement analyses: DPU (dividend distribution by units) and FFO (fund from operations) in order to investigate whether these two ratios gave significantly different results during the Covid 19 crisis. However, this paper deals with further methods of measuring the performance of REITs, namely P/FFO, payout ratio, debt-ebitda and interest coverage. The objective of this paper is to compare these four stocks and their performance to assess which stock has performed the best in the past.
Digitalisation of the economy and the issues of inequality in the global society
Authors: Đorić Žarko
Published: March 2023

Increasing prosperity, as well as the coexistence of persistent and deep inequalities, is one of the greatest paradoxes of our time, which in today's world undermines the entire modernisation process and global development dynamics. Undoubtedly, the digital revolution is transforming economies on a global scale, bringing with it huge potential economic gains and new challenges. In an era of complex economic, technological, geopolitical and environmental risks, the so-called growing social fragmentation is particularly striking, among other things, through the strong spread of digital inequalities (and the related concept digital divide), which further undermines social cohesion and global cooperation. Although digital progress has created enormous wealth in record time, it has remained concentrated around a small number of individuals, companies and countries, and all predictions are that this trajectory will continue, further deepening already growing inequality. The paper analyses the inequalities and stratification of the digital sphere and seeks to establish a link between sustainable development, rapid technological change and issues of inequality, and thus encourages debate and reflection on this challenge for researchers and public practitioners in the global context, by applying scientific methods of systematisation and analysis. In the coming period, new policies under the auspices of the new agenda will have to respond much better to the new dynamics of the digital economy in order to record more inclusive results in the global world. In a world where more than half of citizens have no or limited internet access, intensive work must be done to close the digital divide (especially in internet access), while inclusiveness would be crucial to building a digital economy that delivers for all, which is crucial for economic mobility and social participation. In order to turn the digital transformation curve towards a more prosperous tomorrow, collaborative and coordinated action at the global level is of great importance.
Psychological Service for Ukrainian School Students during the Russian Invasion: Experience of School Psychologists from Kryvyi Rih
Authors: Velykodna Mariana , Deputatov Vladyslav , Kolisnyk Lyudmyla , Shestopalova Olena , Shylo Oksana
Published: March 2023

Introduction: After eight years of the war in the East of Ukraine, two years of the COVID-19 pandemic with relevant lockdowns, and two months of bomb alerts, school students and school psychologists from Kryvyi Rih have been dealing with new brutal military actions during the Russian invasion of Ukraine since the 24th February 2022.

Purpose: This paper focuses on School Psychological Services' changes and challenges caused by the Russian invasion. It assesses war-related psychological effects on school students and school psychologists from Kryvyi Rih.

Method: Brief non-structured interviews and the survey.

Results and Conclusions: After the Russian invasion of Ukraine, School Psychological Services in Kryvyi Rih continued their work remotely, often combining it with in-person meetings (48.5%) and other volunteer activities (27.9%). The surveyed school psychologists (n=48) informed they conducted more individual consultations and psychoeducation and fewer diagnostics than usual to address school students' changing needs in response to wartime. School psychologists felt more effective and involved with students when they believed they got enough support from colleagues and supervisors, learned crisis interventions, received clear guidance, and did not feel burnout. They appreciated current governmental guidance and felt their post-traumatic growth more when they were safe. After 1.5 months of the war, 43.8% of psychologists experienced burnout. At least a quarter needed additional education, psychological support, easily accessible supervision (especially short and rapid), and guidance for specific cases.
Barriers to Exclusive Breastfeeding in Mothers Belonging to Low, Middle, and High Socio-Economic Families in Pakistan
Authors: Khan Sabeen Abid , Ali Naurin , Maroof Fatima , Fatima Hussain Syeda Namayah
Published: March 2023

Introduction: Exclusive breastfeeding (EBF) for the first six months of life improves health and increases infant survival. In Asia, Pakistan ranks second in child mortality. Socioeconomic status (SES) is an important predictor of healthy behaviors. The study aims to understand the barriers to exclusive breastfeeding faced by mothers from different socioeconomic classes in Pakistan.

Method: The cross-sectional study was done in the Pediatric outpatient department (OPD) of Shifa International hospital and community health center from November 2020 to 1 March 2021. Mothers and their children 1 to 3 years of age were included in the study.

Results: A total of 175 mothers and their children were included. EBF for the first six months was done by 120 (68.6%). However, by one year of age, only 99 (56%) continued breastfeeding. Out of these 175 mothers, 79 (45%) were from the lower class, 69 (39.4%) were from the middle class, and 27 (15.4%) were from upper SES. Among the lower, middle, and high socioeconomic classes frequency of EBF practiced by mothers was 51, 54, and 15 (p 0.03), respectively. Pre-lacteals were given to 102 (58.2%). This practice was more frequent in lower SES families (0.03). The majority of working women belonged to upper SES (0.04). Mothers in the upper class are least likely to EBF their children (OR 0.5 CI 0.2-1.3). The adjusted odds ratio for EBF is highest for lower SES mothers, followed by the middle class.

Conclusion: Support from family, place and mode of delivery, working mothers, and high socioeconomic class are important factors affecting exclusive breastfeeding in Pakistan.
Daigou: Transnational Flows, Relatedness, and the Reproduction of the Chinese Family
Authors:   ,   Aarhus University, Sandal Meina Jia
Published: March 2023

This dissertation discusses the impact and meaning of transnational daigou (buying-on-behalf-of) businesses, where Chinese immigrants, primarily women, supply networks of kin and friends in China with infant formula bought in Denmark. The circulation of goods and capital between consumers and suppliers results in an extensive transnational network based on mutual trust and morality. In this respect, the daigou practices constitute both vertical intergenerational and horizontal transnational forms of relatedness, which in different ways contribute to solving the conundrum of family reproduction in contemporary China and the Chinese diaspora.
Creaky Voice in American English: How Are American Women Who Use Creaky Voice Perceived?
Authors: Meier Pernille
Published: March 2023

Vocal fry is a voice quality that can be found in different varieties of English and is used by many different speakers. Nonetheless, it is considered an emerging female voice quality that impairs their work opportunities. The study of the perception of vocal fry has gained attention in the last few years. However, there is a lack of literature reviews comparing the speech evaluations done for vocal fry. In this article eight papers were compared and evaluated. This article not only demonstrated how important the choice of voice sample, evaluator and methodology is to the outcome of the findings but also references possible consequence the choice of an artificial vocal fry and free speech had on the perception of vocal fry in American English.
Scientific photography and astronomy: Technology applied to understanding the universe
Authors: Abalos Vazquez Fernando , Ábalos Javier
Published: March 2023

In 1925, Edwin Hubble took the first step towards increasing the size of the known universe by several orders of magnitude using the precarious photographic methods available at the time: glass plates and photosensitive emulsions. Analysing periodic variations in the brightness of certain stars (Cepheids) through photographs, Hubble was able to show that the distance between Andromeda and the Earth was much greater than previously thought. Thus, Andromeda, previously thought to be a nebula, had to be a galaxy different from our own. Suddenly, the estimated size of the universe went from a few hundred thousand light years to a few billion light years. Since then, the synergy between photographic technology and astronomy has continued to grow.
Una imagen y mil palabras: El binomio fotografía y ciencia
Authors: García-Roa Roberto
Published: March 2023

La fotografía nace a principios del siglo XIX como una herramienta con la que retratar el mundo que nos rodea. Con su aparición, la comunidad científica encontró una aliada con la que traspasar las fronteras del conocimiento. Desde entonces, el binomio fotografía y ciencia ha evolucionado notablemente. La fotografía se ha posicionado no solo como una vía eficaz en la toma de datos, sino también como una herramienta con la que compartir información científica, tanto dentro como fuera del mundo académico. Además, el desarrollo tecnológico de las últimas décadas promueve una interacción casi continuada de la ciudadanía –incluida la comunidad investigadora– con la fotografía. Este hecho ha abierto aún más las opciones a través de las cuales la fotografía puede integrarse en el desarrollo de la carrera científica.
Madame Davit: Gaudir de la natura: La il·lustració botànica des de la perspectiva de gènere
Authors: Viladomiu Àngels , Romo Àngel
Published: March 2023

Suzanne Davit (París, 1897–Barcelona, 1973) és poc coneguda i estudiada, tot i la rellevància del seu llegat en la il·lustració botànica catalana de començament i de mitjan segle xx. Grans botànics com Pius Font i Quer van valorar molt la seva manera única de copsar la natura. Dona, artista, apassionada de la natura i científicament molt curiosa, va representar les plantes d’una manera diferent de l’habitual de l’època. Les seves innovacions s’interpreten com un discurs artístic alternatiu al patriarcal dominant i com una manifestació de l’empremta femenina. L’accés a documents inèdits –la correspondència de Davit amb una amiga– ens ha permès reconstruir algunes claus del seu treball, en el qual conflueixen l’exaltació estètica de les flors i la perspectiva de gènere.
¿Qué sabemos del consumo digital de los menores?
Authors: Montaña Blasco Mireia
Published: March 2023

El consumo de contenidos digitales e inadecuados ha sido noticia, recientemente, por las consecuencias negativas que puede tener en los menores. Este consumo ha ido incrementándose, en los últimos años, por la facilidad de acceder a él en nuestra vida diaria. A pesar de la existencia de una regulación específica para proteger a los niños en el consumo de contenidos audiovisuales, en medios tanto tradicionales como digitales, todavía existen riesgos y desafíos que se deben abordar para garantizar su seguridad y bienestar.
Justicia social, datos, justicia de datos: breves notas en conversación con Emiliano Treré y Guiomar Rovira
Authors: Roig Antoni
Published: March 2023

Durante la primera semana de marzo tuvimos la suerte de poder compartir tiempo e ideas con dos grandes figuras expertas en movimientos sociales y activismo digital: los profesores Emiliano Treré (Universidad de Cardiff) y Guiomar Rovira (Universidad de Girona). Aceptaron el reto de mantener una conversación, que resultaría apasionante, sobre justicia de datos, activismo en la era de los datos, algoritmos y la importancia de las pequeñas acciones para el cambio social, incluso ante causas aparentemente perdidas. Este es un pequeño adelanto que espero sirva a modo de inmersión en una cuestión fundamental en los complejos tiempos que vivimos.
Symphonic Principles of Development in Chinese Piano Concertos of the 1980s - Early 2000s
Authors: Van Tszyasin' , Zagidullina Zalina Zakirovna
Published: March 2023

In the 1980s and early 2000s, Chinese composers wrote the largest number of piano concertos in the entire century-long history of this genre in the musical history of this state. Among them, the most recognized in different countries were the works of Huang Anlun and Du Mingxin. Along with the fame of the pianists who performed them and the importance of the composers themselves in the music of China, a considerable merit in this is seen in the enrichment of their concerts with symphonic principles that influenced the depth of dramatic tension in these works. The article examines the techniques of musical development in two concerts by Huang Anlun and the First and Third Concerts by Du Minxin in line with the ideas of symphonism laid down by B. Asafyev and developed in the works of Soviet and Russian musicologists. The role of Russian music in the appeal of Chinese composers to symphonic drama in piano concerts is also noted. The main means of symphonization in the concerts under consideration mostly coincide. They are characterized by the orchestrality of the piano part and the developed dialogicity of the soloist and orchestra, moreover, there is a high degree of their cohesion in the works of Huang Anlun. The figurative transformation of themes is of key importance. Meanwhile, there are differences. Du Mingxin tends to a more concise form of the concert. With regard to thematic work, he confines himself to creating arched connections and tends to bring contrasts closer together. Huang Anlun builds monumental musical canvases. He permeates his compositions with leittems and pays great attention to development. So, if Du Mingxin acts within the framework of a symphonized concert, then Huang Anlun has made an exit to the concert-symphony genre.
Molecular docking of Vitamin D3 Receptor (VDR) with potential herbal substance as ligand to prevent excessive hair loss in menopausal women
Authors:   Universitas Indonesia, Parawangsa Aditya , Sugito Syailendra Karuna ,   Universitas Indonesia, Ayu Ananda Latifa Ariestiana ,   Universitas Indonesia, Dinda Safira Nadya ,   Universitas Indonesia, Ayuthaya Shafa ,   Universitas Indonesia, Rahmalia Az Zahra Raissa ,   Universitas Indonesia
Published: March 2023

Hair loss is commonly found in menopausal women. Hair loss is one of the consequences of hormonal dynamics when a woman stops having menstrual cycle, which affect calcium and vitamin D level in the body. Although it is clear enough that hormonal adjustment is required, older people and another sociodemographic factor prefer herbal-based therapeutic rather than synthetic-based due to tradition and positive experience factors. This study is an in-silico study which aims to point out the possible ligand candidates that can work as Vitamin D Receptor (VDR) agonists. We perform molecular docking using Autodock version 4.2 with the criteria of Lamarckian GA. VDR (PDB ID: 1TXI) was docked with ten compounds and one native ligand, then analyzed using Autodock 4.2. Dolichosterone, Gartanin, and (-)-Matairesinol, Luteolin, 5-HETE, Sinapyl glucoside, and geraniol, in order shows smallest to bigger binding energy when simulated in the software (-9.72, -7.70, -7.20, -6.88, -5.76, -5.71 kcal/mol). Thus, we found that these compounds are potential to become VDR agonist. Further research is still required to determine each compound drug potential and maximize therapeutic concentration for medicinal purposes.
Geografía rural latinoamericana: temas de investigación y perspectivas de futuro
Authors: Alvarado Sánchez Meylin
Published: March 2023

O livro é fruto do convênio entre a UERJ e a Universidade Nacional da Costa Rica (UNA), com o objetivo de trazer a público a dinâmica dos estudos no âmbito da geografia rural da região latino-americana. As abordagens da relação entre campo e cidade na América Latina ganharam novos contornos a partir da tendência dos espaços rurais de se desenvolverem também na área do turismo, agronegócios, agroindústrias rurais e em outros serviços, sem se restringirem a atividades agrícolas. Esse panorama afetou o cenário do campo e o espaço urbano, ocasionando diferentes critérios teóricos e metodológicos de pesquisa acadêmica, assim como a descoberta de novos objetos de estudo, revelados nesta coletânea. A publicação integra pesquisadores dos países da América Latina, e o conjunto de capítulos evidencia a diversidade e a relevância dos estudos realizados.
Spatiotemporal organisation of human sensorimotor beta burst activity
Authors: Zich Catharina , Quinn Andrew J , Bonaiuto James J , O'Neill George , Mardell Lydia C , Ward Nick S , Bestmann Sven
Published: March 2023

Beta oscillations in human sensorimotor cortex are hallmark signatures of healthy and pathological movement. In single trials, beta oscillations include bursts of intermittent, transient periods of high-power activity. These burst events have been linked to a range of sensory and motor processes, but their precise spatial, spectral, and temporal structure remains unclear. Specifically, a role for beta burst activity in information coding and communication suggests spatiotemporal patterns, or travelling wave activity, along specific anatomical gradients. We here show in human magnetoencephalography recordings that burst activity in sensorimotor cortex occurs in planar spatiotemporal wave-like patterns that dominate along two axes either parallel or perpendicular to the central sulcus. Moreover, we find that the two propagation directions are characterised by distinct anatomical and physiological features. Finally, our results suggest that sensorimotor beta bursts occurring before and after a movement can be distinguished by their anatomical, spectral, and spatiotemporal characteristics, indicating distinct functional roles.
Evidence for virus-mediated oncogenesis in bladder cancers arising in solid organ transplant recipients
Authors: Starrett Gabriel J , Yu Kelly , Golubeva Yelena , Lenz Petra , Piaskowski Mary L , Petersen David , Dean Michael , Israni Ajay , Hernandez Brenda Y , Tucker Thomas C , Cheng Iona , Gonsalves Lou , Morris Cyllene R , Hussain Shehnaz K , Lynch Charles F , Harris Reuben S , Prokunina-Olsson Ludmila , Meltzer Paul S , Buck Christopher B , Engels Eric A
Published: March 2023

A small percentage of bladder cancers in the general population have been found to harbor DNA viruses. In contrast, up to 25% of tumors of solid organ transplant recipients, who are at an increased risk of developing bladder cancer and have an overall poorer outcomes, harbor BK polyomavirus (BKPyV). To better understand the biology of the tumors and the mechanisms of carcinogenesis from potential oncoviruses, we performed whole genome and transcriptome sequencing on bladder cancer specimens from 43 transplant patients. Nearly half of the tumors from this patient population contained viral sequences. The most common were from BKPyV (N=9, 21%), JC polyomavirus (N=7, 16%), carcinogenic human papillomaviruses (N=3, 7%), and torque teno viruses (N=5, 12%). Immunohistochemistry revealed variable Large T antigen expression in BKPyV-positive tumors ranging from 100% positive staining of tumor tissue to less than 1%. In most cases of BKPyV-positive tumors, the viral genome appeared to be clonally integrated into the host chromosome consistent with microhomology-mediated end joining and coincided with focal amplifications of the tumor genome similar to other virus-mediated cancers. Significant changes in host gene expression consistent with the functions of BKPyV Large T antigen were also observed in these tumors. Lastly, we identified four mutation signatures in our cases, with those attributable to APOBEC3 and SBS5 being the most abundant. Mutation signatures associated with an antiviral drug, ganciclovir, and aristolochic acid, a nephrotoxic compound found in some herbal medicines, were also observed. The results suggest multiple pathways to carcinogenesis in solid organ transplant recipients with a large fraction being virus-associated.
HUWE1 controls tristetraprolin proteasomal degradation by regulating its phosphorylation
Authors: Scinicariello Sara , Soderholm Adrian , Schäfer Markus , Shulkina Alexandra , Schwartz Irene , Hacker Kathrin , Gogova Rebeca , Kalis Robert , Froussios Kimon , Budroni Valentina , Bestehorn Annika , Clausen Tim , Kovarik Pavel , Zuber Johannes , Versteeg Gijs A
Published: March 2023

Tristetraprolin (TTP) is a critical negative immune regulator. It binds AU-rich elements in the untranslated-regions of many mRNAs encoding pro-inflammatory mediators, thereby accelerating their decay. A key but poorly understood mechanism of TTP regulation is its timely proteolytic removal: TTP is degraded by the proteasome through yet unidentified phosphorylation-controlled drivers. In this study, we set out to identify factors controlling TTP stability. Cellular assays showed that TTP is strongly lysine-ubiquitinated, which is required for its turnover. A genetic screen identified the ubiquitin E3 ligase HUWE1 as a strong regulator of TTP proteasomal degradation, which we found to control TTP stability indirectly by regulating its phosphorylation. Pharmacological assessment of multiple kinases revealed that HUWE1-regulated TTP phosphorylation and stability was independent of the previously characterized effects of MAPK-mediated S52/S178 phosphorylation. HUWE1 function was dependent on phosphatase and E3 ligase binding sites identified in the TTP C-terminus. Our findings indicate that while phosphorylation of S52/S178 is critical for TTP stabilization at earlier times after pro-inflammatory stimulation, phosphorylation of the TTP C-terminus controls its stability at later stages.
Neuroelectrophysiology-compatible electrolytic lesioning
Authors: Bray Iliana E , Clarke Stephen E , Casey Kerriann M , Nuyujukian Paul ,   for the Brain Interfacing Laboratory
Published: March 2023

Lesion studies have historically been instrumental for establishing causal connections between brain and behavior. They stand to provide additional insight if integrated with multielectrode techniques common in systems neuroscience. Here, we present and test a platform for creating electrolytic lesions through chronically implanted, intracortical multielectrode probes without compromising the ability to acquire neuroelectrophysiology. A custom-built current source provides stable current and allows for controlled, repeatable lesions in awake-behaving animals. Performance of this novel lesioning technique was validated using histology from ex vivo and in vivo testing, current and voltage traces from the device, and measurements of spiking activity before and after lesioning. This electrolytic lesioning method avoids disruptive procedures, provides millimeter precision over the extent and submillimeter precision over the location of the injury, and permits electrophysiological recording of single-unit activity from the remaining neuronal population after lesioning. This technique can be used in many areas of cortex, in several species, and theoretically with any multielectrode probe. The low-cost, external lesioning device can also easily be adopted into an existing electrophysiology recording setup. This technique is expected to enable future causal investigations of the recorded neuronal population’s role in neuronal circuit function, while simultaneously providing new insight into local reorganization after neuron loss.
Identification of candidate mitochondrial inheritance determinants using the mammalian cell-free system
Authors: Zuidema Dalen , Jones Alexis , Song Won-Hee , Zigo Michal , Sutovsky Peter
Published: March 2023

The degradation of sperm-borne mitochondria after fertilization is a conserved event. This process known as post-fertilization sperm mitophagy, ensures exclusively maternal inheritance of the mitochondria-harbored mitochondrial DNA genome. This mitochondrial degradation is in part carried out by the ubiquitin-proteasome system. In mammals, ubiquitin-binding pro-autophagic receptors such as SQSTM1 and GABARAP have also been shown to contribute to sperm mitophagy. These systems work in concert to ensure the timely degradation of the sperm-borne mitochondria after fertilization. We hypothesize that other receptors, cofactors, and substrates are involved in post-fertilization mitophagy. Mass spectrometry was used in conjunction with a porcine cell-free system to identify other autophagic cofactors involved in post-fertilization sperm mitophagy. This porcine cell-free system is able to recapitulate early fertilization proteomic interactions. Altogether, 185 proteins were identified as statistically different between control and cell-free-treated spermatozoa. Six of these proteins were further investigated, including MVP, PSMG2, PSMA3, FUNDC2, SAMM50, and BAG5. These proteins were phenotyped using porcine in vitro fertilization, cell imaging, proteomics, and the porcine cell-free system. The present data confirms the involvement of known mitophagy determinants in the regulation of mitochondrial inheritance and provides a master list of candidate mitophagy co-factors to validate in the future hypothesis-driven studies.
Hilsen til Liv Merete Nielsen fra Notoddenmiljøet
Authors: Carlsen Kari , Gulliksen Marte Sørebø
Published: March 2023

Liv Merete Nielsen har hatt en nøkkelfunksjon innenfor utviklingen av forskning på områdene forming, formgiving, design, kunst og håndverk i Norge. Arbeidet ved hennes faste institusjon, OsloMet, er velkjent. Men hennes arbeid ved Universitetet i Sørøst-Norge (USN), tidligere Høgskolen i Telemark (HiT), er kanskje mindre kjent.
Folkloric Manifestation of Primitive Impulses: Folk Riddles
Authors:   Iğdır University, Iğdır, Turkey, Abalı İsmail
Published: March 2023

It is known that factors stemming from human nature play an active role in the emergence of riddles, which are one of the oral products. It is obvious that the riddle as a genre, which is thought to have been born and developed for purposes such as having fun, having a good time, arousing curiosity, and solving the unknown, has deep traces of the psychological structure of the human being. In this study, the effect of basic impulses on riddles is discussed with different dimensions. The research is based on document analysis and it was conducted on Turkish riddles that were established with obscene associations with a decent answer, creating a threatening perception and containing insult and cursing, and the samples belonging to the genre were analyzed from a psychoanalytic perspective. At the end of the study, some inferences were made such as the one to the effect that sexuality and aggression impulses can be satisfied without being subjected to any censorship thanks to the peculiar structure and characteristics of riddles.
‘Have You Heard of Kalevauva.fi Yet?’ Modern Folklore, Humour, and Gender in the Lyrics of the Finnish Folk Troubadour Duo Kalevauva.fi
Authors:   University College London, London, United Kingdom, Doesburg Charlotte , Valijärvi Riitta-Liisa ,   University College London, London, United Kingdom,   Department of Modern Languages, Uppsala University, Sweden
Published: March 2023

This article explores the lyrics of the Finnish folk duo Kalevauva.fi. The duo uses extracts from online forums and other social media. We argue that this method of song-writing is a prime example of modern folklore as it reflects the collective, anonymous creativity of people and is reminiscent of the compilation of the Finnish national epic Kalevala. The humour in the lyrics is used to create a sense of community and discuss taboos. It rises from incongruity, for example by mismatch between melodies and lyrical content. We relate the lyrics to internet memes, and examine stereotypical and alternative representations of Finnish men. We place Kalevauva.fi in the context of the Kalevala process as well as contemporary music making.
Political Meanings Hidden Behind Enchanting Melodies: How China Delivered Ideological Messages in the Song Cycle “Four Seasons of Our Motherland”
Authors:   Zhengzhou Preschool Education College, China, Zhao Jun , Zhao Marianne ,   Zhengzhou Preschool Education College, China
Published: March 2023

Music draws influence from its surroundings and thus, with its political and social setting, becomes a part of the dynamic relationship. The aim of this article is to investigate and introduce this particular feature in the context of Chinese culture and explain, with the help of Zheng Qiufeng’s song cycle “Four Seasons of Our Motherland”, how politics play a part next to folk music elements, enchanting melodies, and patriotic lyrics. The song cycle in question was chosen as an example of how politics can be subtly included in the musical plot. It is one of the very few Chinese song cycles, the most well-known one, and made unique by the inclusion of minority characteristics from different Chinese regions together with its distinctive ideological mission.
Economic costs of invasive rodents worldwide: the tip of the iceberg
Authors: Diagne Christophe , Ballesteros-Mejia Liliana , Cuthbert Ross N. , Bodey Thomas W. , Fantle-Lepczyk Jean , Angulo Elena , Bang Alok , Dobigny Gauthier , Courchamp Franck
Published: March 2023

Background

Rodents are among the most notorious invasive alien species worldwide. These invaders have substantially impacted native ecosystems, food production and storage, local infrastructures, human health and well-being. However, the lack of standardized and understandable estimation of their impacts is a serious barrier to raising societal awareness, and hampers effective management interventions at relevant scales.

Methods

Here, we assessed the economic costs of invasive alien rodents globally in order to help overcome these obstacles. For this purpose, we combined and analysed economic cost data from the InvaCost database—the most up-to-date and comprehensive synthesis of reported invasion costs—and specific complementary searches within and beyond the published literature.

Results

Our conservative analysis showed that reported costs of rodent invasions reached a conservative total of US$ 3.6 billion between 1930 and 2022 (annually US$ 87.5 million between 1980 and 2022), and were significantly increasing through time. The highest cost reported was for muskrat Ondatra zibethicus (US$ 377.5 million), then unspecified Rattus spp. (US$ 327.8 million), followed by Rattus norvegicus specifically (US$ 156.6 million) and Castor canadensis (US$ 150.4 million). Of the total costs, 87% were damage-related, principally impacting agriculture and predominantly reported in Asia (60%), Europe (19%) and North America (9%). Our study evidenced obvious cost underreporting with only 99 documents gathered globally, clear taxonomic gaps, reliability issues for cost assessment, and skewed breakdowns of costs among regions, sectors and contexts. As a consequence, these reported costs represent only a very small fraction of the expected true cost of rodent invasions (e.g., using a less conservative analytic approach would have led to a global amount more than 80-times higher than estimated here).

Conclusions

These findings strongly suggest that available information represents a substantial underestimation of the global costs incurred. We offer recommendations for improving estimates of costs to fill these knowledge gaps including: systematic distinction between native and invasive rodents’ impacts; monetizing indirect impacts on human health; and greater integrative and concerted research effort between scientists and stakeholders. Finally, we discuss why and how this approach will stimulate and provide support for proactive and sustainable management strategies in the context of alien rodent invasions, for which biosecurity measures should be amplified globally.
Systematic review of marine environmental DNA metabarcoding studies: toward best practices for data usability and accessibility
Authors: Shea Meghan M. , Kuppermann Jacob , Rogers Megan P. , Smith Dustin Summer , Edwards Paul , Boehm Alexandria B.
Published: March 2023

The emerging field of environmental DNA (eDNA) research lacks universal guidelines for ensuring data produced are FAIR–findable, accessible, interoperable, and reusable–despite growing awareness of the importance of such practices. In order to better understand these data usability challenges, we systematically reviewed 60 peer reviewed articles conducting a specific subset of eDNA research: metabarcoding studies in marine environments. For each article, we characterized approximately 90 features across several categories: general article attributes and topics, methodological choices, types of metadata included, and availability and storage of sequence data. Analyzing these characteristics, we identified several barriers to data accessibility, including a lack of common context and vocabulary across the articles, missing metadata, supplementary information limitations, and a concentration of both sample collection and analysis in the United States. While some of these barriers require significant effort to address, we also found many instances where small choices made by authors and journals could have an outsized influence on the discoverability and reusability of data. Promisingly, articles also showed consistency and creativity in data storage choices as well as a strong trend toward open access publishing. Our analysis underscores the need to think critically about data accessibility and usability as marine eDNA metabarcoding studies, and eDNA projects more broadly, continue to proliferate.
Tesis Evaluación de instrumentos económicos para la mitigación de emisiones de GEI provenientes de la ganadería bovina en Chile
Authors:   ,   Pontificia Universidad Católica de Chile. Facultad de Agronomía e Ingeniería Forestal, Báez Quiñones Nadia
Published: March 2023

El sector agropecuario en Chile es responsable del 11% de las emisiones de GEI, específicamente el consumo de 1 kg de carne de bovinos semanal representa el 14% de la cuota de emisión de un chileno. El objetivo de este trabajo es evaluar el efecto del uso de instrumentos económicos para mitigar las emisiones de GEI provenientes de la ganadería bovina en Chile. Se proyectaron dos posibles escenarios de comportamiento del stock de ganado de carne y leche en Chile a partir de modelos de regresión lineal. Luego se estimaron las emisiones del sector según la metodología del IPCC. Se simuló el efecto de tres escenarios de impuestos (bajo, medio y alto) a las emisiones bovinas y tres escenarios de impuestos al consumo de carne y leche de vaca respectivamente. Se demostró que el impuesto a las emisiones redujo significativamente las mismas, pero elevó abruptamente los costos de producción, sobre todo de la leche. El impuesto al consumo de leche demostró tener mejores resultados. La reducción de emisiones fue mayor que el incremento en precios y la disminución del consumo; contrariamente al impuesto al consumo de carne debido fundamentalmente al efecto de las elasticidades de ambos productos. Se concluyó que los impuestos al consumo tienen un efecto más equitativo, ya que afecta tanto a la producción nacional como a las importaciones.
Arquitectura (y) narrativa : museografía de San Francisco de la Alameda 1929-2020
Authors:   ,   Pontificia Universidad Católica de Chile. Escuela de Arquitectura, Hamilton Diego J.
Published: March 2023

Esta tesis busca levantar y registrar arquitectónicamente los diferentes modelos y detalles museográficos que han conformado al Museo de Arte Colonial de San Francisco a lo largo de los años, un programa inscrito en un conjunto arquitectónico de más de 400 años de antigüedad. Esto se hace por medio de una documentación compuesta de 3 partes: un levantamiento arquitectónico preciso del claustro en la actualidad, luego, un registro graficado de su colección fija más notable, que es la serie de 54 pinturas del S.XVII sobre la vida de San Francisco, y finalmente, una reconstrucción temporal que cruza estos dos materiales producidos con registros fotográficos, entrevistas, textos y otros tipos de fuentes de investigación que informan el contexto arquitectónico y disposición de los cuadros. Entendiendo a los museos como una pieza de arquitectura pública, activa y con poder ideológico y socio-cultural, el fin de éste estudio es, por un lado, comprender e identificar de mejor manera la carga cultural que subyace al conjunto arquitectónico más antiguo de Santiago, sirviendo a futuras intervenciones patrimoniales y reformulaciones museológicas que pretendan llevarse a cabo de manera informada y proactiva sobre un edificio icónico de la Iglesia Católica y de Chile. Y por otro lado, abrir una discusión sobre la manera en que la arquitectura juega un rol curatorial sobre una colección permanente de museo, e incidentalmente, sobre una narrativa.
Espacios intersticiales : oportunidades de reconversión del Zanjón de la Aguada en el área urbana sur poniente de la Región Metropolitana
Authors:   ,   Pontificia Universidad Católica de Chile. Escuela de Arquitectura, Cedano Cabrera María Josefina
Published: March 2023

En el análisis del entramado urbano de ciudades contemporáneas, la presencia de vacíos dejados por el desarrollo, crecimiento, expansión de la ciudad, y por la implementación de infraestructuras necesarias para esto, constituye un ámbito relevante dada la magnitud de algunas de estas superficies y la posición estratégica que en muchos casos estos vacíos asumen. En ese sentido, en el caso de la matriz urbana de la Región Metropolitana, se evidencian diversos vacíos de gran escala, entre los cuales se destacan aquellos asociados a los intersticios producidos por el cruce de la infraestructura vial e hídrica de la ciudad. Lugares en abandono tanto físico, histórico como jurisdiccional, pero a su vez lugares con gran potencial de reconversión al espacio público; libres y abiertos a acoger un nuevos usos y programas. En el área sur poniente de Santiago, encontramos una serie de vacíos interconectados en torno al Zanjón de la Aguada, la autopista del sol y el límite sur de la comuna de Estación Central. La amplia superficie de este sistema de intersticios lo configura como una pieza territorial de magnitud Metropolitana. La investigación propone visibilizar y explorar posibilidades programáticas para estos vacíos urbanos insertos en la ciudad, generados por el crecimiento urbano y el cruce de infraestructuras. Se busca regenerar esta pieza urbana según estrategias sociales y ecológicas, tomando en cuenta su geografía, emplazamiento lineal y sesgo social, a través de la potencial relación entre paisaje como nueva infraestructura y el vacío existente. El proyecto pretende entonces la activación de la pieza con acciones que colonicen el territorio y den pie o gatillen proyectos posteriores en el lugar.