bluuebunny/crossref_metadata_2025 huggingface dataset:
The Specialist Treatment of Inpatients: Caring for Diabetes in Surgery (STOIC-D Surgery) Trial: A Randomized Controlled Trial of Early Intervention With an Electronic Specialist-Led Model of Diabetes Care
Authors: Barmanray Rahul D. , Kyi Mervyn , Colman Peter G. , Rowan Lois , Raviskanthan Mayurapriya , Collins Lucy , Donaldson Laura , Montalto Stephanie , Tsan Joshua , Sun Emily , Le Minh , Worth Leon J. , Thomson Benjamin , Fourlanos Spiros
Published: January 2024

OBJECTIVE

To investigate the effect of early intervention with an electronic specialist-led “proactive” model of care on glycemic and clinical outcomes.

RESEARCH DESIGN AND METHODS

The Specialist Treatment of Inpatients: Caring for Diabetes in Surgery (STOIC-D Surgery) randomized controlled trial was performed at the Royal Melbourne Hospital. Eligible participants were adults admitted to a surgical ward during the study with either known diabetes or newly detected hyperglycemia (at least one random blood glucose result ≥11.1 mmol/L). Participants were randomized 1:1 to standard diabetes care or the intervention consisting of an early consult by a specialist inpatient diabetes team using electronic tools for patient identification, communication of recommendations, and therapy intensification. The primary outcome was median patient-day mean glucose (PDMG). The key secondary outcome was incidence of health care–associated infection (HAI).

RESULTS

Between 12 February 2021 and 17 December 2021, 1,371 admissions met inclusion criteria, with 680 assigned to early intervention and 691 to standard diabetes care. Baseline characteristics were similar between groups. The early intervention group achieved a lower median PDMG of 8.2 mmol/L (interquartile range [IQR] 6.9–10.0 mmol/L) compared with 8.6 mmol/L (IQR 7.2–10.3 mmol/L) in the control group for an estimated difference of −0.3 mmol/L (95% CI −0.4 to −0.2 mmol/L, P < 0.0001). The incidence of HAI was lower in the intervention group (77 [11%] vs. 110 [16%]), for an absolute risk difference of −4.6% (95% CI −8.2 to −1.0, P = 0.016).

CONCLUSIONS

In surgical inpatients, early diabetes management intervention with an electronic specialist-led diabetes model of care reduces glucose and HAI.
A Case of Trichobezoar in an Adolescent Female
Authors: Abu-Jeyyab Mohammad
Published: January 2024

Introduction: Trichobezoar is a condition where hair builds up in the stomach, forming a mass that resembles a ball. Since human hair is resistant to peristalsis and digestion, it eventually builds up in the folds of the stomach. Affected individuals with trichotillomania and tricophagia have a propensity to pull out their own hair and consume it. Nearly all of the cases of the condition are in females. Case presentation: Several days prior to her presentation, a 13-year-old female patient arrived at the emergency room complaining of epigastric pain, frequent vomiting episodes, chronic abdominal discomfort, and weight loss. Upon clinical examination, a 20 X 15 cm epigastric mass that descends to the umbilicus is found. All of the laboratory tests came back clean. Ultrasonography and a simple abdominal x-ray were not specific. In order to demonstrate the presence of a significant filling defect extending to the second part of the duodenum within the stomach, a barium meal was performed. An upper endoscopy was performed for additional confirmation and revealed a large trichobezoar that was gastric-confined. This enormous hairy mass was removed through surgery. The post-operative recovery took place without a hitch and produced satisfactory results. Conclusion: Trichobezoar is an extremely rare condition that may be encountered during surgical practice; a high index of suspicion is required for diagnosis, and endoscopy remains the gold standard method for investigation and diagnosis. The primary treatment method is open surgery. All patients require psychiatric consultation and long-term monitoring
Developing AI for Weather Prediction
Authors: Lukacz Przemyslaw Matt
Published: January 2024

The question of how professional and lay communities develop trust in new technologies, and automation in particular, has been a matter of lively debate. As a charismatic technology, artificial intelligence (A.I.) has been a common topic of these debates. This paper presents a case study of how the discourses and principles of ethics of technology development—specifically, of A.I.— were mobilized to form trust among actors in the fields of computer science, risk communication, and weather forecasting. My analysis draws on sociology of expertise and the literature on ethics of A.I. to ask: how emerging networks of expertise use ethics to overcome mistrust in technology? And, what role does the institutionalization of those networks play in the process of trust formation? I situate this discussion on the NSF Institute for Research on Trustworthy A.I. The Institute is positioned as a mediating organization with the goal of increasing trust in this technology primarily the weather forecasting community, but also among the public. I show that first, to better understand how scientific and professional fields react to increased automation it is crucial to unpack the historical backdrop of how the professional identity of those experts has been shaped by a relationship with computer-supported modeling. To this end, I situate the discussion in the long-standing tensions between computer modelling and tacit knowledge in weather forecasting. Second, I argue that the means of establishing trust in A.I. propagated by the actors in the paper, which pair norms of explainability to sensitivity to professional intuitions and domain-specific conventions, rely on a series of “mutual orientations” (Edwards, 1996). I mobilize the concept of “mutual orientations” to describe the work of tailoring the ethics of A.I. to the specific requirements of weather sciences, but also to the vision of a national strategy of investment in this technology.
EMPLOYEE APPRAISAL PERFORMANCE, WORKPLACE, ORGANIZATIONAL CULTURE AND ITS EFFECT ON THE EMPLOYEE PERFORMANCE
Authors: Putri Husni Indrawati Wijaya , Suwitho Suwitho
Published: January 2024

This research aims to investigate the effect of Employee Performance Appraisal through Employee Performance, Workplace through Employee Performance, and Organization Culture on the Employee Performance of educative employees at Wijaya Kusuma University Surabaya. The population of this research was the employees of Wijaya Kusuma University Surabaya, such as educative employees and non-educative employees. On the other hand, the researcher used the employees as the study sample with 100 people. In the data analysis technique, the researcher used simple random sampling to gather the data by using a questionnaire to the 100 employees. Moreover, in the data analysis technique, the researcher used regresi linear berganda. The result shows that employee appraisal performance, Workplace, and organizational culture significantly affect employee performance of the educative employee of Wijaya Kusuma University Surabaya. With increasing employee performance, the researcher hopes that Wijaya Kusuma University will become one of the most outstanding Universities and superior in the world of education in Indonesia.
Luxury tourism experiences: Wales
Authors: Harkison Tracy , Low Tiffany
Published: January 2024

The hiatus that COVID-19 caused enabled tourism policy makers worldwide to reconsider the luxury tourism experience. They could examine what they were offering and how they could attract luxury tourists after the pandemic. Tourism New Zealand (NZ) conducted a survey to gain a clear understanding of the luxury tourism drivers that high net worth individuals (HNWIs) have in order to create an appeal to NZ. This survey was mirrored by two academics (one from Wales and one from NZ) for the Welsh tourism sector. A case study approach was taken with a sequential multi-phase design which included an online survey completed by 733 HNWI’s from 9 countries. The findings provided governments and destination management organisations with insights and practical tools to evaluate and develop their offerings in a way that would provide memorable and distinctive luxury tourism experiences in Wales.
Influencing exhibitor loyalty through trust and value cocreation: The moderating effect of visit frequency
Authors: Lee Jiwon , Ryan Chris
Published: January 2024

This study examines relationships between trust, value co-creation, and loyalty in the exhibitions industry. It tests a new model of value co-creation and the role of exhibitors as co-creators with host organizations in a Business-to-Business context. Existing literature has concentrated on exhibitor performance and outcomes and has generally disregarded the power to enhance value co-creation, participation, and citizenship behaviours for conference hosts and exhibitors. The study contributes to an understanding of how trust and citizenship behaviours positively influence customer satisfaction and exhibitor loyalty, and in addition takes into account the frequency of past attendance as a moderating variable.
Design and Development of a Bowling Machine for Effective and Efficient Cricket Batting Training
Authors:   Department of Engineering Technology, Faculty of Technology, Sabaragamuwa University of Sri Lanka, Belihuloya 70140, SRI LANKA, Kumara Buddhika Sampath ,   Department of Mechanical Engineering, Faculty of Engineering, University of Moratuwa, Katubedda, Moratuwa 10400, SRI LANKA
Published: January 2024

Cricket is one of the most popular sports in the world. For the batters to practice, there could be a requirement for an effective and efficient device to mimic different bowling variations to enhance the training sessions. This research consists of computer aided design, simulation, and fabrication of a robust cricket bowling machine to achieve target bowling for effective training of cricket batters. A novel ball propelling mechanism was designed with two degrees of freedom movements of a pair of rotating wheels. Mechanisms for sudden speed changes were also tested with prototypes during this design. However, for acceptable product compactness and cost, the design was prototyped without the sudden speed changing concept. The base is maintained on a bi-axial precise tilting gyroscopic mechanism. This tilting mechanism accurately adjusts the delivery point of the ball with respect to a two-axis system, which helps to control the line and length of the ball. The novel ball propelling mechanism enhances the stability of controlling in pitching position, ball rotation axis, and ball speed. Controlling these parameters effectively creates an environment for efficient practice sessions for batsmen. Target bowling is the main objective of this study and the machine intends to mimic the vast bowling variations.
Regression Analysis of Heart Rate for Driving Fatigue using Box-Behnken Design
Authors:   Faculty of Manufacturing Engineering, Universiti Teknikal Malaysia Melaka, Hang Tuah Jaya, 76100 Durian Tunggal, Melaka, MALAYSIA, Kamat Seri Rahayu
Published: January 2024

There are few road accident studies that use heart rate as an indicator of driver fatigue. This study offers a mathematical regression analysis to discover which independent variables (driving speed, driving duration, body mass index, gender, and types of roads) are significant in influencing the heart rate and how these parameters interact to indicate driver fatigue. The analysis is conducted using a Box-Behnken design by Design Expert software. The results revealed that the values of Prob>F for all variables were less than 0.01%, indicating that all variables influence heart rate significantly. The heart rate increased when driving speed, driving duration, and body mass index (BMI) increased. A similar pattern was observed as the driving path shifted from urban to a moderately difficult uphill/downhill road. However, the pulse rate was reduced when a female driver was replaced by a male driver. The model's accuracy was evaluated by comparing the output data obtained from actual road driving with software prediction. First, the prediction interval of both techniques' output data was within 95%, meeting the minimum quantitative criteria of a 90% predictive interval. Subsequently, the residual errors were less than 10%. The regression model will be useful to shed light on traffic safety measures for preventing fatigue-related road accidents.
Effect of fused deposition modeling process parameter in influence of mechanical property of acrylonitrile butadiene styrene polymer
Authors: Subramani Raja , Kalidass Arun Kumar , Muneeswaran Mohan Dass , Gantala Lakshmipathi Balaji
Published: January 2024

The objective of this study is to investigate how the mechanical properties of components produced using acrylonitrile butadiene styrene (ABS) on a Creality Ender-3 3D printer are affected by various fused deposition modeling (FDM) printing parameters. The impact of various factors, including infill density, printing speed, platform temperature, extruder temperature, and so on, was assessed in terms of their influence on the ultimate tensile strength, yield strength, and elastic modulus of the manufactured components. The impact of each parameter was assessed using a Multi-criteria decision-making (MCDM) methodology. Finally, the second set of parameters, including a 35% infill thickness, 0.25 mm layer level, 40 mm/s printing speed, 75 °C platform temperature, 210 °C extruder temperature, and 75 mm/s travel speed, was discovered to be the most suitable for ABS filament used to make impellers.
Water mites and their use as bioindicators of water quality conditions: a Pennsylvania case study
Authors: Stenger Logan R. , Ferguson Francesca M. , Skvarla Michael
Published: January 2024

Water mites (Acariformes: Hydrachnidia) are one of the planet's most diverse and abundant groups of aquatic arthropods. With more than 7,500 described species, water mites have been documented in nearly every known freshwater environment. In lotic systems, water mites are commonly found in fast-flowing, riffle-run stream habitats, where one square meter of substrate can contain as many as 5,000 individual mites representing more than 50 species, 30 genera, and all 8 superfamilies. Despite their widespread distribution, relative diversity, and abundance, water mites have been widely neglected in freshwater biomonitoring efforts. However, several studies across the globe have found that water mites can be used as successful bioindicators of water quality conditions. Thus, the following study provides one of the first detailed examinations of lotic water mites and their bioindicator potential in North America. We sampled water mites from sites along 'attaining' (unpolluted) and agriculturally 'impaired' (polluted) riffle-run stream habitats and compared their assemblages to other physicochemical and benthic macroinvertebrate metrics used to quantify water quality in Pennsylvania. In total, we collected 9,139 individual water mites representing 5 superfamilies, 9 families, and 14 genera from both attaining (n = 13) and impaired (n = 13) streams. Similar to other global studies, we found significant differences between the water mite assemblages of attaining and impaired streams, with attaining streams having greater richness and diversity of water mites. Our data shows that several mite taxa are associated with biological and physicochemical conditions of water quality, where some known sensitive taxa are increasingly dominant in attaining streams and less dominant in impaired streams. Conversely, some pollution-tolerant taxa dominance increases in impaired streams while sensitive taxa abundance declines. These findings illustrate that water mites vary in their sensitivity to pollution and are suitable bioindicator species whose inclusion in biomonitoring assessments will increase assessment accuracy.
Condylar position in correction of dentofacial deformities
Authors: Hase Michael P.
Published: January 2024

The mandibular condyles are a reliable reference point for diagnosing soft and hard tissue disharmony of the face and dental structures. Ignoring the seated positron of the condyles may lead to derangements of the joint and relapse of treated malocclusion cases. Muscle releaseis required to record a reproducible condylar positron and a simple technique is described. Once the record is made, meaningful radiograms can be taken to demonstrate the true dentoskeletal deformity. The mounting of dental casts is more accurate if a resilient recording material is used rather than soft wax. This same record should be used when taking cephalometric radiograms to ensure there has been no pivoting of the mandible with luxation of one or both condyles from the fossae. True sagittal and horizontal plane disharmonies can be accurately diagnosed and hence treated if the mandibular condyles are in their seated position when the face and dentition are being evaluated.
CARACTERIZAÇÃO MULTIFUNCIONAL DA AGRICULTURA FAMILIAR EM ASSENTAMENTOS RURAIS DE CAMPO MAIOR, PIAUÍ
Authors: De Carvalho Diogo Augusto Frota , Gomes Jaíra Maria Alcobaça
Published: January 2024

Objetivo: Caracterizar a multifuncionalidade da agricultura familiar nos assentamentos rurais Fazenda Boa Vista e Brejinho, em Campo Maior, Piauí.
Referencial Teórico: A agricultura familiar nos assentamentos rurais é multifuncional por ensejar quatro dimensões: socioeconômica, tecido social e cultural, segurança alimentar e preservação dos recursos naturais. A caracterização dessas dimensões permite compreender o território, promovendo debates que podem contribuir na construção de políticas públicas de desenvolvimento.
Método: Foram realizadas pesquisas de campo, com coleta e análise de dados mediante visitas técnicas, turnês-guiadas e aplicação de formulários semiestruturados com 56 famílias, em 56 lotes.
Resultados e conclusões: A agricultura familiar multifuncional nos assentamentos Fazenda Boa Vista e Brejinho, embora possibilite práticas culturais e técnicas sustentáveis, não garante a segurança alimentar e nem a renda principal dos assentados, carecendo de apoio mais eficiente das políticas públicas, em especial de assistência técnica. Também foram constatados impactos ambientais nos territórios, como desmatamento e queima do lixo.
Implicações da Pesquisa: A caracterização multifuncional da agricultura familiar adotada se mostrou profícua, possibilitando a avaliação sistêmica dos assentamentos rurais, o qual pode auxiliar nas políticas públicas de gestão desses assentamentos.
Originalidade/valor: O método de caracterização baseado na multifuncionalidade da agricultura familiar permite uma análise social, econômica e ambiental detalhada dos assentamentos rurais, podendo ainda ser adotado em pesquisas similares.
A theory of shadow money flow monitoring in present-day realities
Authors: BATURINA Evgeniya V.
Published: January 2024

Subject. This article discusses the issues related to shadow economy and threats to Russia's economic security. Objectives. The article aims to analyze approaches to systematization of shadow economy elements. Methods. For the study, I used the methods of comparative, formal and logical, and structural analyses, as well as the expert assessment method. Results. The article proposes an original definition of shadow money flow and a developed scheme for monitoring the movement of funds on bank accounts of economic entities, which makes it possible to identify the shadow cash flow. Relevance. The results of the study can be used when monitoring and assessing the effectiveness of law enforcement agencies and other government agencies' activities aimed at identifying and preventing offenses in the economic sphere.
Rare Cause of Acute Scrotal Pain in Pediatric Age
Authors: Tavares Ariana , Miranda Rui , Reis Alcinda , Costa Miguel
Published: January 2024

The most common causes of acute scrotal pain in the pediatric age group include testicular torsion, torsion of the testicular appendages, and epididymitis. There are five testicular epididymal appendages described in the literature.
Young Patient with HIV Presented with STEMI and Triple Vessel Disease
Authors: Tasheva Iveta , Serafimov Nikolay , Koleva-Ignatova Irina
Published: January 2024

nfection with the human immunodeficiency virus is characterized by an acquired and irreversible immunosuppression, which predisposes the patient to multiple infections with opportunistic germs and neoplasms, which can affect the vast majority of organs. The heart, which was initially thought to be exempt from this rule, was shown, to be affected right from the first phase of Human immunodeficiency virus (HIV) infection. Cardiac damage, as the initial sign of HIV infection, is extremely rarely reported, on the other hand, cardiac damage demonstrable by echocardiography and anatomo-pathology is much more frequent than the clinical manifestations suggest.
Una reflexión sobre la praxis dentro de la praxis de la formación del analista
Authors: Stavchansky Liora
Published: January 2024

La formación del analista no solo remite al estudio o difusión de textos, ni tampoco al propio análisis, incluye en su trayecto a la época, los movimientos históricos y discursivos que nos habitan desde principios de siglo XX. Tanto Sigmund Freud como Jacques Lacan –en su diferencia– formularon preguntas por la formación, la función, la posición y la transmisión del analista, es decir, expusieron interrogantes que desde entonces problematizan elementos teóricos, prácticos, éticos y subjetivos para sostener la praxis del psicoanálisis. Estas preguntas no implican únicamente los temas mencionados, sino que además apuntan a evidenciar y experimentar (en tanto hacer experiencia a partir de un acontecimiento) el trazo de la formación misma. No se trata de validarla, ni de hacer una especie de evaluación, tampoco de la suma de saberes o eventos realizados, puesto que su camino (el de la formación) escapa a la pedagogía y al entorno universitario.
reformas administrativas en el gobierno del Estado de Veracruz, periodo 2010-2016
Authors: López Romero Dulce Yaneth
Published: January 2024

En México se ha implementado una gran cantidad de reformas administrativas bajo el paraguas de la Nueva Gestión Pública, lo que ha sido estudiado por autores como Aguilar (1996), Pardo y Berber (2016), Dussauge (2009), entre otros, a nivel federal, sin embargo a nivel subnacional esto no ha sido documentado, por lo que un análisis a nivel estatal nos permite identificar algunas de las principales reformas efectuadas en el periodo 2010-2016. En este artículo se hará una revisión de las principales reformas administrativas efectuadas en el Gobierno del Estado de Veracruz, durante el periodo 2010-2016, realizando una investigación documental de los instrumentos de reforma utilizados para su implementación, con el objetivo de demostrar los resultados de la aplicación de las herramientas de la Nueva Gestión Pública, tales como la reducción de estructuras organizativas por parte del Gobierno del Estado de Veracruz, al cierre del sexenio 2010-2016. Para tal fin se utilizó el método descriptivo. Los resultados muestran que los intentos por reducir el aparato burocrático fueron fallidos.
 
Administrative reforms in the government of the State of Veracruz, period 2010-2016
Abstract: In Mexico, a large number of administrative reforms have been implemented under the umbrella of the New Public Management, which has been studied by authors such as Aguilar (1996), Pardo & Berber (2016), Dussauge (2009), among others, at the federal level, however at the subnational level this has not been documented, so an analysis at the state level allows us to identify some of the main reforms carried out in the period 2010-2016. In this article we will review the main administrative reforms carried out in the Government of the State of Veracruz, during the period 2010-2016, conducting documentary research of the reform instruments used for their implementation, with the aim of demonstrating the results of the application of the tools of the New Public Management, such as the reduction of organizational structures by the Government of the State of Veracruz, at the end of the six-year period 2010-2016. For this purpose, the descriptive method was used. The results show that the attempts to reduce the bureaucratic apparatus were unsuccessful.
Derechos humanos en el espacio docente asistencial
Authors: Fernández Cañedo Lauro , Gertrudis-Santamaría Irene , Vargas Cazares Beatriz , García Duaré , Delgado-Domínguez Carolina , Ortega Pineda Lizbeth Aida , García-Ortiz Osvaldo Ulises
Published: January 2024

El internado médico de pregrado es un proceso formativo fundamental para la adquisición de competencias necesarias para la práctica de la medicina general, ambos son regulados por diversas instituciones con la finalidad de garantizar un funcionamiento dentro de un marco que permita el cumplimiento de los derechos humanos. Sin embargo, dado el entorno de alta exigencia inherente a los servicios de salud, tanto el sector estudiantil como académico pueden verse vulnerados sus derechos bajo determinadas situaciones. Se realizó un estudio cuantitativo prospectivo aplicando a los tres grupos la “escala de disfrute de los derechos humanos de los médicos residentes (DERES)”, validada por el Observatorio de Educación Médica (2021), modificada en el periodo agosto 2021. Se observó en el grupo de médicos becarios que al menos 1 de cada 4 desconocen sus derechos como estudiantes dentro del espacio docente asistencial, asimismo, más del 50% desconoce el protocolo indicado a seguir en caso de vulneración de sus derechos.
 
Human rights in the teaching care space: Perception of their enjoyment by Internal Physicians
Undergraduate medical internship is a fundamental educational process for acquiring the necessary competencies for general medical practice, both of which are regulated by various institutions with the aim of ensuring functioning within a framework that allows for the fulfillment of human rights. However, given the high-demand environment inherent in healthcare services, both the student and academic sectors may have their rights violated under certain situations. A prospective quantitative study was conducted, applying the "Enjoyment of Human Rights Scale for Resident Physicians (DERES)" to the three groups, validated by the Medical Education Observatory (2021) and modified in August 2021. It was observed in the group of medical interns that at least 1 in 4 are unaware of their rights as students within the teaching-assistant space. Furthermore, over 50% are unaware of the recommended protocol to follow in case of rights violation.
Análisis de legislación mexicana sobre derecho al acceso y participación de patrimonios
Authors: Becerra Zavala María De Lourdes , Lozada Andrade Zazil Elideth , Andrade Sosa Perla Génesis
Published: January 2024

El Observatorio de Políticas Culturales analizó, de febrero a junio de 2023, 9 legislaciones federales y estatales (de Veracruz de Ignacio de la Llave), en materia de patrimonio cultural material e inmaterial, para distinguir los mecanismos normativos e institucionales que garantizan el derecho de acceso y participación en la vida cultural en materia de patrimonios. A través del análisis neoconstitucionalista, se identificaron las entidades responsables del diseño e implementación de políticas culturales, y sus atribuciones legales, para garantizar el mencionado derecho cultural. Mientras más contemporáneas son las legislaciones, existe mayor apego a la garantía del derecho cultural, aunque no contemple todos los elementos recomendados por la ONU. Se concluye que la segunda década del siglo XXI es el momento histórico del reconocimiento y garantía de los derechos culturales en México, y es urgente actualizar los instrumentos normativos a nivel local en ese sentido.
 
Analysis of Mexican legislation on the right of access and participation of patrimonies
Abstract: The Observatory of Cultural Policies analyzed, from February to June 2023, 9 federal and state legislations (of Veracruz de Ignacio de la Llave), regarding tangible and intangible cultural heritage, to distinguish the normative and institutional mechanisms that guarantee the right of access and participation in cultural life in terms of heritage. Through the neoconstitutionalist analysis, the entities responsible for the design and implementation of cultural policies, and their legal attributions, were identified in order to guarantee the aforementioned cultural right. The more contemporary the legislation, the greater the adherence to the guarantee of cultural rights, even if it does not contemplate all the elements recommended by the UN. It is concluded that the second decade of the 21st century is the historic moment for the recognition and guarantee of cultural rights in Mexico, and it is urgent to update regulatory instruments at the federal and state levels in this regard.
Je pars de Diary Sow et Cacophonie de Ken Bugul : entre fuite et fugue
Authors:   Universidad de Granada (España), Molina Romero Mª Carmen
Published: January 2024

Ken Bugul’s and Diary Sow’s novels outline a poetics and an aesthetics of flight as a leitmotif of African women’s writing. The two Senegalese writers convey self-exploration schemes and symbolic itineraries that lead the protagonists, their own alter egos, to liberation. Whether a brilliant young woman full of future promise or a weakening elderly widow, both heroines face the problem of space –inner, Euclidean, sexual, linguistic and maternal–. A space governed by dogmatisms that prevent women from rejoicing in displacement. Cacophonie is the story of a solitude, an errantry and a deconstruction; Je pars is the one of the affirmation of an I-speaker whose utterance is finally aware of its own power.
El tratamiento del espacio en la pieza Quatre femmes et le soleil de Jordi Pere Cerdà
Authors:   Universidad de Zaragoza (España), Marqués Meseguer Josep
Published: January 2024

"The play Quatre femmes et le soleil (1980 [2004]) by Jordi Pere Cerdà (Saillagouse, 1920-Perpignan, 2011), pseudonym of Antoine Cayrol, delves into the psychological tensions of some characters who profoundly portray the author’s contemporary rural and Pyrenean society, located in Cerdagne (on its French side) during the years of resistance against German occupation in World War II. Through this paper we will delve into the psychological complexity of each subject from an interest in spatiality, in order to appreciate to what extent the intimacy of the characters is built from the connection of their desires and frustrations with their surroundings, essentially, the natural space of the Cerdagne’s region "
Victor Segalen, l’écrivain incertain
Authors:   Université Hassan II de Casablanca (Maroc), Ouchari Said
Published: January 2024

"This contribution examines the dual reception of Victor Segalen. Within Segalenian critics, there is a divergence, even a tension, which has been little studied. This dual reception includes scholars who present Segalen with a comprehensive approach to otherness, with clear ideological positions in his questioning of Christianity and deconstruction of colonial myths. Other critics take the opposite approach, relativizing the idea of the writer as open to intercultural exchange and hostile to the phenomenon of colonization. In fact, many critics have shown that Segalenian critics have consistently misinterpreted the traveler as a defender of other cu."
In-silico Study of Methyl Beta D-xylopyranoside: A Spectroscopically Screened Small Molecule from Aganosma dichotoma
Authors: Kosanam Sreya , Pasupula Rajeshwari
Published: January 2024

Background: To develop scientific evidence of unexplored traditional plants. Methods: Standardization of leaf powder was done as per World Health Organization (WHO) guidelines, followed by fourier-transform infrared spectroscopy (FTIR) analysis to identify basic phytoconstituents. Preliminary phytochemical analysis and spectroscopic analysis was done to validate the identified phytoconstituents. Molecular docking was done to identify a small molecule, methy beta D-xylopyranoside. Results: The air-dried leaves and barks were powdered and subjected to extraction based on the polarity of solvents through soxhlation, namely, methanol, ethanol, and chloroform, to obtain four different extracts. Further, preliminary phytochemical tests and qualitative determination of the different biologically active compounds from leave powder Aganosma dichotoma using FTIR revealed the presence of different phytoconstituents. And gas chromatography-mass spectrometry of crude extracts revealed different chemical entities with varying quantities and followed by in-silico molecular docking studies of hub genes against the photochemical small molecule. Thus, the identification of different biologically active compounds in the extracts of leaves A. dichotoma warrants further biological and pharmacological studies. Conclusion: Small molecules identified from A. dichotoma have robust activity against myocardial infarction, but need to be validated through in-vitro and in-vivo studies.
EFFECTIVENESS OF WETLAND-BASED WAVE AND OPTICS MODULES ON STUDENTS' SCIENTIFIC LITERACY ABILITIES
Authors: Khairunnisa Yasmine , Hafizah Ellyna
Published: January 2024

Wetlands that dominate the area in South Kalimantan are one of the indigenous science learning resources that can help students learn. However, the insertion of wetlands has not commonly been done on a learning media which directly used in class. The developed wetlands-based module on wave and optics aimed to enhance students’ scientific literacy which leads to the success of learning by integrating indigenous science. It was implemented for thirty science education students by using a group pretest-posttest design. The results showed that 29 students gained increased scientific literacy during the implementation, with the improvement in each aspect of scientific literacy categorized as moderate. In addition, the Wilcoxon test result showed a significant enhancement of scientific literacy after using the wetlands-based module of wave and optics. Thus, the wetland-based module is effective in improving students’ scientific literacy abilities.
Faktor-Faktor Kerentanan dan Upaya Mitigasi Bencana Banjir di Sub-Daerah Aliran Sungai, Kasus: Kecamatan Tangse, Kabupaten Pidie
Authors: Wulandari Elysa , Sari Ayu Maya , Sabila Farisa
Published: January 2024

Kecamatan Tangse adalah salah satu kecamatan di Kabupaten Pidie yang berada pada Pengunungan Bukit Barisan dengan kondisi karakteristik topografi wilayah berkontur yang beragam menjadikan Tangse memiliki daerah akumulasi genangan (cekungan) sehingga Kecamatan Tangse menjadi daerah rawan bencana banjir. Banjir menyebabkan korban jiwa, kerugian material dan rusaknya infrastruktur. Tujuan penelitian ini yaitu mengetahui faktor-faktor kerentanan bencana banjir di Kecamatan Tangse Kabupaten Pidie dan upaya mitigasi bencana banjir. Jenis penelitian yang dilakukan yaitu kualitatif deskriptif dengan menggunakan variabel kerentanan (fisik, sosial, ekonomi dan lingkungan). Menggunakan metode analisis skala likert dengan pendekatan rasionalisme bersumber pada teori dan kebenaran empirik. Hasil dari penelitian ditemukan 7 faktor yang berpengaruh secara signifikan ialah faktor curah hujan (10,7%), kelerengan (8,8%), lokasi atau jarak rumah ke sungai (8,7%), selanjutnya di ikuti dengan faktor jenis tanah, kondisi sungai, kepadatan bangunan, dan material bangunan. Upaya mitigasi yang dilakukan dalam bentuk mitigasi non struktural dan mitigasi struktural.
In Silico Screening of Compounds Similar to Codeine, Tramadol, and Morphine with Better Pharmacodynamic and Pharmacokinetics Profiles
Authors:   Department of Pharmacology and Pharmacognosy, Kabarak University School of Pharmacy, Kenya, Faith Kamakia , Stephen Ouma ,   Department of Pharmacology and Pharmacognosy, Kabarak University School of Pharmacy, Kenya, Kagia Richard ,   Department of Pharmacology and Pharmacognosy, Kabarak University School of Pharmacy, Kenya
Published: January 2024

Introduction: Pain alleviation is the primary intervention in promoting quality of life. Among the compounds used in management of pain are opioids. Codeine is mostly used as antitussive and is commonly present in cough syrups. Tramadol and Morphine are used as analgesics based on severity of pain. Although these drugs provide instant pain relief, they are associated with many side effects and the most worrying once are addiction, respiratory depression and tolerance. Methods: Codeine, Tramadol, and Morphine were used as query compounds to generate similar compounds using SwissSimilarity. Similar compounds were docked to mu, kappa, and delta receptors and those that showed better docking scores to mu receptor and lower scores to kappa and delta were analyzed for toxicity profiles using ProTox II and pharmacokinetics profiles using SwissADME. Results: ZINC13831510; 0.992, ZINC03629718; 0. 995; ZINC03870350; 0.993; ZINC28256912; 0.992; and ZINC71774151; 0.977 showed highest binding score to mu receptors and lower to both kappa and delta. All compounds were predicted to inhibit CYP2D6 enzyme. All compounds permeated Blood Brain Barrier with the exceptions of ZINC04102208; 0.992; and ZINC13831510; 0.992. Tramadol, its zinc compounds and ZINC03629718; 0.995. were not substrates for P-glycoprotein. Tramadol and ZINC03639132; 0.976; were predicted immunoactive. All compounds conformed to Lipinski rule of five. Conclusion: In conclusion, ZINC13831510; 0.992; showed the highest binding score to morphine. ZINC02509756; 0.986; and ZINC26259212; 0.995; were considered the safest as compared to Tramadol and Codeine and their zinc compounds respectively. Further invitro studies are recommended for the following promising compounds ZINC13831510; 0.992, ZINC03629718; 0. 995; ZINC03870350; 0.993; ZINC28256912; 0.992; and ZINC71774151; 0.977 ZINC02509756; 0.986; and ZINC26259212; 0.995;.
The effect of storytelling of old restaurant on positive emotion and loyalty
Authors:   The Table and Food Coordinate Society of Korea, Kim Do Hoon , Kim Kyung Tae
Published: January 2024

This study aims to explore the impact of storytelling in long-established restaurants on positive emotions and customer loyalty. Storytelling was categorized into historical and experiential narratives, while positive emotions and loyalty were analyzed as a single factor. The study focused on patrons of restaurants in Seoul with over 30 years of history, employing convenience sampling as a method. Conducted online via Google, the survey sought to validate various hypotheses. The results showed that both historical (Hypothesis 1-1) and experience-based storytelling (Hypothesis 1-2) significantly influenced positive emotions. Positive emotions, in turn, were found to impact loyalty (Hypothesis 2). While historical storytelling had a positive effect on loyalty (Hypothesis 3-1), experience-based storytelling did not (Hypothesis 3-2). This research contributes to the existing body of knowledge by examining the specific effects of storytelling on the emotions and loyalty of customers in old restaurants. The findings offer foundational data on restaurant patronage and practical management strategies for restaurant operations. Additionally, the study builds upon existing theoretical research, offering both academic and practical insights into the effects of storytelling in the restaurant industry.
A REVIEW ON THE INVASIVE VEGETABLE LEAF MINER (Diptera: Agromyzidae): LIFE CYCLE, DAMAGE SYMPTOMS, AND MANAGEMENT
Authors: Paudel Prava , Paudel Pragya , Timilsina Richa , Basnet Pratibha
Published: January 2024

The leaf miner is a juvenile stage of insects that dwell within the leaves of vegetables and feed on their tissues. It belongs to the family of dipteran flies and has a polyphagous feeding habit, meaning it can consume a wide range of plants. This comprehensive review paper provides an in-depth analysis of the invasive vegetable leaf miner, covering topics such as its life cycle, damage symptoms, and management strategies. The vegetable leaf miner is an invasive pest that causes significant damage to vegetable crops, particularly solanaceous crops. The paper explores the biology and ecology of the vegetable leaf miner, including its life cycle and host range. It also describes the damaging symptoms caused by the pest, which include the formation of distinctive tube patterns on the leaves. The paper further investigates the various management strategies that have been developed to control the spread of the vegetable leaf miner, including chemical, cultural, and biological control measures. The aim of this paper is to provide a comprehensive overview of the invasive vegetable leaf miner and to highlight the most effective management strategies for controlling its spread and minimizing its impact on crop yields.
RISK PROBLEMS IN ENGAGING IN FOOD FRANCHISING BUSINESS IN SAN PABLO CITY, LAGUNA
Authors: B. Puyo Raciel Carissa
Published: January 2024

Many business owners today operate franchise businesses despite the potential risks they might face. This study assessed the risk problems of Food Franchising Business in San Pablo City, Laguna. The objective of the study is to help local entrepreneurs who intend to engage in food franchising. The respondents of the study were local entrepreneurs with 3 to 7 years in franchising businesses. A descriptive research method was used in the research. A total of 40 respondents answered the questionnaire. Statistical tools used to determine the risk problems are mean and standard deviation. The results identified the following risks in engaging into the food franchising business: profitability, payback period, and sustainability. Pearson Correlation Coefficient was used at a .05 level of significance to determine the significant relationship of the risk problems identified with the type of food franchising businesses. Results show that there is significant relationship between the risk problems profitability, payback period and sustainability with the type of food franchising businesses.
COMPARATIVE ECONOMIC ANALYSIS OF MAIZE GRAIN AND SEED PRODUCTION IN HETAUDA SUB- METROPOLITAN CITY, MAKWANPUR
Authors: Poudel Puspa , Poudel Suraj , Dhungana Asmita , Dahal Arjun , Joshi Newar Saurabh , Rijal Komal , Dahal Bienam
Published: January 2024

Maize is considered as second most important cereal crops in Nepal. In the hills of Nepal, such as Makwanpur, it dominates all other crop cultivation. Hence, a study was conducted for comparative assessment of socio-economic condition and to identify major problems of maize grain and seed production in Makwanpur. The data were obtained through the survey of 66 producers, 33 each of maize grain and seed producers, in March 2022. The data was then coded and imported into MS Excel, where it was analyzed using Excel and SPSS software. Benefit-cost ratio, Cobb-Douglas production function, mean t-test, and other descriptive statistics were calculated and compared between maize grain and seed producers. Socio-demographic characteristics of both the grain and seed producers were similar with exceptions in education, religion, etc. The inputs (FYM and labor) contributed 65% and 67% of the total cost incurred for grain and seed production respectively. The cost and return from seed production was higher than that of grain production. The B.C. ratio for grain and seed producers was 1.026 and 1.144 respectively. Nonetheless, seed producers sold only 34% of total output as seed, with the remaining portion being used as grain, however, marketing all of the potential seeds will result in higher benefits. Diseases and pest problems were ranked as most severe problem hindering efficient maize production in the study area.
INHIBITION PROFICIENCY OF Al 3+ ON MILD STEEL CORROSION IN DIFFERENT pH AQUEOUS MEDIUM
Authors: Islam Md. Saiful , Sakairi Masatoshi
Published: January 2024

The effect of pH on the inhibition performances of Al3+ on mild steel corrosion in Cl- aqueous solution has been investigated by immersion tests and electrochemical tests. Immersion tests results showed that the rate of corrosion in higher pH solution was decreased as compared to the lower and intermediate pH. Scanning electron microscopic observation elucidated that the lower number of pits and grain boundaries on the sample immersed in higher pH solution as compared to lower pH solutions. The electrochemical impedance spectroscopic results showed the highest charge transfer resistance in higher pH solution, and supported the results obtained from the immersion tests. X-ray photoelectron spectroscopic results elucidated a protective layer was formed on the steel surface immersed in the higher pH solution that was associated with Al(OH)3. Therefore, it was suggested that the protective layer on the steel surface immersed in the higher pH solution inhibited the corrosion reactions.
ENSURING THE FUTURE OF RENEWABLE ENERGY: A CRITICAL REVIEW OF RELIABILITY ENGINEERING APPLICATIONS IN RENEWABLE ENERGY SYSTEMS
Authors: Gidiagba Joachim Osheyor , -Ehiobu Nwakamma Ninduwezuor , Ojunjobi Oluwaseun Ayo , Ofonagoro Kelechi Anthony , Daraojimba Chibuike
Published: January 2024

As the global shift toward sustainable energy intensifies, the reliability and robustness of renewable energy systems become paramount. This research article offers a comprehensive examination of the pivotal role that reliability engineering plays in optimizing the efficiency, longevity, and dependability of these renewable systems. Delving into varied energy domains, from solar and wind to geothermal and bioenergy, the study elucidates the challenges and breakthroughs in ensuring consistent energy outputs amidst the inherent uncertainties of renewable sources. The study exploration also highlights the innovative intersection of emerging technologies, such as artificial intelligence and predictive maintenance, in augmenting the reliability of these green energy systems. Through real-world case studies, the research paper provides insights into the tangible benefits and lessons drawn from effective reliability engineering applications. Conclusively, the paper posits actionable recommendations for both policymakers and engineers, emphasizing the indispensable nature of reliability engineering in shaping a resilient renewable energy future. This study serves as a seminal reference for stakeholders aiming to enhance the sustainability and dependability of the next generation of renewable energy systems.
Absence of the RING domain inMID1results in patterning defects in the developing human brain
Authors: Frank Sarah , Gabassi Elisa , Käseberg Stephan , Bertin Marco , Zografidou Lea , Pfeiffer Daniela , Brennenstuhl Heiko , Falk Sven , Karow Marisa , Schweiger Susann
Published: January 2024

The X-linked form of Opitz BBB/G syndrome (OS) is a monogenic disorder in which symptoms are established early during embryonic development. OS is caused by pathogenic variants in the X-linked geneMID1. Disease-associated variants are distributed across the entire gene locus, except for the N-terminal really interesting new gene (RING) domain that encompasses the E3 ubiquitin ligase activity. By using genome-edited human induced pluripotent stem cell lines, we here show that absence of isoforms containing the RING domain of MID1 causes severe patterning defects in human brain organoids. We observed a prominent neurogenic deficit with a reduction in neural tissue and a concomitant increase in choroid plexus-like structures. Transcriptome analyses revealed a deregulation of patterning pathways very early on, even preceding neural induction. Notably, the observed phenotypes starkly contrast with those observed in MID1 full-knockout organoids, indicating the presence of a distinct mechanism that underlies the patterning defects. The severity and early onset of these phenotypes could potentially account for the absence of patients carrying pathogenic variants in exon 1 of theMID1gene coding for the N-terminal RING domain.