bluuebunny/crossref_metadata_2025 huggingface dataset:
Investigating the Customer Journey in Second‐Hand Fashion Platforms: Implications for Luxury Brand Management
Authors: Murtas Gabriele , Pedeliento Giuseppe
Published: November 2024

Consumers' increasing environmental concerns are prompting a shift in fashion consumption, fueling the remarkable growth of the second‐hand market. Over the last decade, this trend has spurred the emergence of a plethora of online platforms dedicated to the resale of pre‐loved fashion items. As consumers can easily access luxury garments at affordable prices through second‐hand platforms, the rapid expansion of these indirect channels holds the potential to further redefine how consumers experience and access luxury, significantly contributing to its democratization. While scholarly interest in second‐hand luxury has recently surged, current research has overlooked the experience consumers live when purchasing from such channels. Our research aims to fill this gap by delving into the customers' journey within these marketplaces, unraveling their experiences, perceptions, and decision‐making processes when purchasing second‐hand luxury. Twenty‐four in‐depth interviews with established luxury consumers who have recently purchased second‐hand luxury items through these platforms were conducted. The customer experience and journey framework was applied as a theoretical lens to make sense of such interactions. The findings reveal that consumers are drawn by the perceived endless availability of luxury items and the opportunity to compare different listings. Still, concerns over brand dilution, counterfeiting, and the absence of a sought‐after luxury experience pose significant challenges during the customer journey. This research contributes to the emerging field of second‐hand luxury by shedding light on the intricacies of the customer experience within these platforms. The article concludes with managerial insights aimed at assisting luxury brand managers in developing strategies and tactics in a market environment where second‐hand platforms are gaining momentum.
Innovative Pyrazole Hybrids: A New Era in Drug Discovery and Synthesis
Authors: Bendi Anjaneyulu , Devi Poonam , Sharma Harsh , Yadav Geetanjali , Raghav Neera , Pundeer Rashmi , Afshari Mozhgan
Published: November 2024

Heterocyclic compounds that include nitrogen and their derivatives have long been regarded as excellent sources of medicinal substances. Pyrazole is a compound with two nitrogen atoms and an aromatic structure. It has several uses and intricate stereochemistry arranged in a five‐membered ring. The knowledge of different pyrazole derivatives and their range of physiological and pharmacological actions has grown significantly in recent years. The scientific community has recently increasingly focused on exploring the chemistry of various pyrazole hybrids due to their enhanced biological activities. This review investigates the chemistry of these diverse pyrazole hybrids, emphasizing their synthesis and their antidiabetic, antibacterial, anticancer, antimicrobial, antioxidant, and anti‐inflammatory activities. Articles published from 2014 onward with an emphasis on the last 5 years are included in this review. This review is anticipated to be useful for future investigations and innovative concepts in the pursuit of designs for creating more promising hybrids of pyrazoles.
Expanded‐Access Use of Elamipretide Improves Quality of Life in Patients With Rare Mitochondrial Disorders Characterized by Ophthalmic Symptoms: A Case Series
Authors: Ansari Sharique , Koenig Mary Kay
Published: November 2024

This case series presents the use of elamipretide in two patients with different progressive mitochondrial disorders (chronic progressive external ophthalmoplegia [CPEO] plus and neuropathy, ataxia, and retinitis pigmentosa [NARP] syndrome) characterized by ophthalmic traits. Elamipretide was well tolerated and both patients demonstrated improvement in symptoms while on therapy.
Vestibular Syncope and Acute Peripheral Vestibular Deficit: A Case Report
Authors: Motta Noemi , Gitto Marco , Castelli Valeria , Tobaldini Eleonora , Montano Nicola , Di Berardino Federica
Published: November 2024

Vestibular syncope is a rare condition in which vertigo may cause syncopal attacks; however, the term has been associated with confusion because it has been ascribed to completely different vestibular and neurological conditions, from dizziness to Menière disease (MD), to the neurovegetative symptoms in benign paroxysmal positional vertigo (BPPV) and central vertebrobasilar hyperfusion. A 75‐year‐old woman with vasodepressive vasovagal syncope, confirmed by a tilt test with trinitrine administration, was referred for an audiological and vestibular assessment showing an acute unilateral peripheral vestibular deficit on the right side. The diagnosis is peripheral acute vestibular deficits. Interventions and outcomes are vestibular treatment and rehabilitation. The patient's vasovagal symptoms immediately improved and were completely resolved. Peripheral vestibular deficits might also trigger syncopal episodes and must be considered and studied by a complete audiological and vestibular evaluation. By restoring the peripheral vestibular function of the right labyrinth after vestibular treatment, a complete long‐term resolution of multiple vasovagal syncopal episodes was observed together with normalization of the tilt test.
Co‐Trimoxazole‐Induced Toxic Epidermal Necrolysis: A Case Report From Nepal
Authors: Gaire Sandesh , Chhetri Suchit Thapa
Published: November 2024

Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe mucocutaneous reactions, often triggered by medications, characterized by blistering and epithelial sloughing. We report the case of a 66‐year‐old male who presented with a 2‐day history of fluid‐filled lesions on his body. On examination, erosions were observed on the posterior and anterior trunk, as well as on both upper and lower limbs. Multiple vesicles and bullae were scattered bilaterally, involving 60%–70% of the body surface area. Co‐trimoxazole‐induced SJS was diagnosed. The patient was admitted to the ICU and treated with dexamethasone, hydrocortisone, imipenem, and azithromycin. Corticosteroids, combined with broad‐spectrum antibiotics, were effective in managing the condition. Early intervention and a multidisciplinary approach helped prevent complications and secondary infections.
Recent Advances in Covalent Organic Framework for Selective Photocatalytic Reduction of CO2
Authors: Deshmukh Shubham Avinash , Bhuse Darpan Vijaykumar , Suresh Selvaraj , Raut Subodh Uttamrao , Kondawar Sharda , Sarkar Sujit , Patel Chandan , Agawane Ganesh
Published: November 2024

Photocatalytic transformation of CO2 into clean fuels and chemicals is a promising solution to address both the energy dilemma and environmental issues. Recent years have seen several efforts to improve the effectiveness and selectivity of CO2 conversion by creating photocatalysts and reduction devices. An alternative to fossil fuels is urgently needed to address the rising energy demand and pollution. Porous heterogeneous catalysts are gaining popularity for carbon capture, with recent breakthroughs in design and application for CO2 conversion. Covalent organic frameworks (COFs) are porous crystalline polymeric materials made up of organic module units held together by strong covalent connections. COFs have numerous applications, including adsorption and separation, detection, catalysis, optoelectronic components, energy storage, and mass transport, due to their low density, massive specific surface area, superior thermal stability, developed pore structure, long‐range sequence, good crystallinity, and excellent tunability of monomer units. In this review, we discuss the synthetic process, morphology, and linkage of COFs. We also elaborate the types of activations for CO2, that is, thermal, electrocatalytic, and photocatalytic activation. Finally, we discuss the application of COFs for conversion of CO2 to value added product (VAC).
Process Understanding of Transamination Reaction in Chiral Pharmaceutical Intermediate Production Catalyzed by an Engineered Amine Transaminase
Authors: Perçin Zeynep , Kleinbeck Florian , Bubenheim Paul , Ruch Thomas , Liese Andreas
Published: November 2024

Chiral amines are key building blocks for the synthesis of many active pharmaceutical ingredients (APIs). Biocatalytic routes offer significant advantages to provide sustainable access to such motifs on commercial scale, with sacubitril valsartan sodium hydrate as a recent example. In this study a deeper mechanistic and kinetic understanding of the central biocatalytic step in the synthesis of sacubitril valsartan sodium hydrate, applying the evolved transaminase CDX‐043, was gained. The equilibrium of the transamination reaction was investigated in detail, and two kinetic models (ping‐pong two‐substrate kinetics and Michaelis–Menten double substrate kinetics) were established, considering substrate and product inhibition. The determined equilibrium constant indicates that the equilibrium lies strongly on the product side. The results of the kinetic studies demonstrate that the transaminase reaction is in conformity with the Michaelis–Menten double substrate kinetic model. Product inhibition was found to be more severe than substrate inhibition. The application of a plug flow reactor (PFR) was shown to be the preferred reactor setup to reduce the occurring inhibition.
Rare Case of Germline GATA2‐Deficiency With Merkel Cell Carcinoma and Acute Myeloid Leukemia
Authors: Yu SooHo , Park Min‐Seung , Kim Gyu Yeong , Cho Junhun , Jung Chul Won , Kim Hee‐Jin , Kim Hyun‐Young
Published: November 2024

Background

Germline GATA2‐deficiency usually manifests as immunodeficiencies and myeloid neoplasms and sometimes with dermatological diseases, including warts, panniculitis, and skin cancers.

Case

We report a 36‐year‐old woman with germline GATA2‐deficiency who developed Merkel cell carcinoma followed by acute myeloid leukemia. Molecular analysis revealed a germline GATA2 S447R variant, not reported from the previous reported case, suggesting a potential association with Merkel cell carcinoma.

Conclusion

This case broadens the spectrum of solid cancers linked to GATA2‐deficiency, emphasizing the need for considering primary immunodeficiency in young patients with myeloid neoplasms or rare skin cancers, facilitating early detection and treatments.
Prognostic Models Using Machine Learning Algorithms and Treatment Outcomes of Papillary Thyroid Carcinoma Variants
Authors: Alshwayyat Sakhr , Kamal Haya , Ghammaz Owais , Alshwayyat Tala Abdulsalam , Alshwayyat Mustafa , Odat Ramez M. , Hanifa Hamdah , Asha Wafa , Saadeh Nesreen A.
Published: November 2024

Background

Hürthle cell (HCC) and columnar cell variants (CCV) are rare subtypes of thyroid cancer.

Aims

This study used machine learning (ML) to evaluate treatment effectiveness and develop prognostic models.

Methods

Chi‐square tests, Kaplan–Meier curves, log‐rank tests, and Cox regression were used. Five ML algorithms constructed prognostic models predicting 5‐year survival, validated using the AUC of the ROC curve.

Results

Among 3690 patients, 3180 had CCV and 510 had HCC. ML models showed metastasis, surgery + RT, and age were significant factors for HCC, while the N component of TNM, metastasis, and tumor size were significant for CCV.

Conclusion

This study offers a comprehensive approach for treating and assessing prognosis in PTC variants. The ML models developed offer practical tools for personalized clinical decision‐making.
The consequence of mismatched buffers in purity checks when spectral cell sorting
Authors: Dapaah Rita A. S. , Ferrer‐Font Laura , Shi Xiaoshan , Hall Christopher , Thompson Sam , Costa Larissa Catharina , Mage Peter L. , Tyznik Aaron J. , Lundsten Kelly , Walker Rachael V.
Published: November 2024

Although spectral flow cytometry has become a ubiquitous tool for cell analysis, the use of spectral cytometry on cell sorters requires additional considerations arising from the unique requirements of sorting workflows. Here, we show that care should be taken when ascertaining the purity of a sort on a spectral cell sorter, as the mismatch of buffers used for initial sample suspension and the buffers used for sort collection can affect the unmixing of the data, potentially giving rise to erroneous purity check results.
Lymph node metastasis risk factors in T2 colorectal cancer
Authors: Morita Yuriko , Kudo Shin‐ei , Takashina Yuki , Ichimasa Katsuro , Kouyama Yuta , Semba Shigenori , Mochizuki Kenichi , Shiina Osamu , Kato Shun , Kuroki Takanori , Shimada Shoji , Nakahara Kenta , Takehara Yusuke , Mukai Shunpei , Ogata Noriyuki , Hayashi Takemasa , Wakamura Kunihiko , Miyachi Hideyuki , Sawada Naruhiko , Nemoto Tetsuo , Baba Toshiyuki , Misawa Masashi
Published: November 2024

Objectives

This study evaluates risk factors for lymph node metastasis (LNM) in T2 colorectal cancer to refine patient selection for endoscopic resection.

Methods

We reviewed records from consecutive patients who had undergone curative surgical resection of T2 colorectal cancer at our institution in Japan between April 2001 and December 2021. Data on conventional clinicopathologic variables were retrieved from the pathology reports at the time of surgery. The clinicopathological features included patient age, sex, tumor diameter, morphology, tumor location, lymphatic invasion, vascular invasion, tumor differentiation, carcinoembryonic antigen and carbohydrate antigen 19‐9 levels, number of lymph node dissections, presence of adenoma component, and LNM.

Results

Among the patients (338 men, 320 women), 170 (25.8%) exhibited LNM. Multivariate logistic regression identified three independent risk factors for LNM: lymphatic invasion (odds ratio [OR], 32.6; 95% confidence interval [CI], 17.3–61.4; p < 0.0001), female sex (OR, 1.70; 95% CI, 1.10–2.62; p = 0.02), and elevated carcinoembryonic antigen levels (OR, 2.56; 95% CI, 1.10–5.96; p = 0.03).

Conclusions

Lymphatic invasion, female sex, and high carcinoembryonic antigen levels significantly increase the risk of LNM in T2 colorectal cancer.
Forecasting the Effects of Global Change on a Bee Biodiversity Hotspot
Authors: Buckner Mark A. , Hoge Steven T. , Danforth Bryan N.
Published: November 2024

The Mojave and Sonoran Deserts, recognized as a global hotspot for bee biodiversity, are experiencing habitat degradation from urbanization, utility‐scale solar energy (USSE) development, and climate change. In this study, we evaluated the current and future distribution of bee diversity, assessed how protected areas safeguard bee species richness, and predicted how global change may affect bees across the region. Using Joint Species Distribution Models (JSDMs) of 148 bee species, we project changes in species distributions, occurrence area, and richness under four global change scenarios between 1971 and 2050. We evaluated the threat posed by USSE development and predicted how climate change will affect the suitability of protected areas for conservation. Our findings indicate that changes in temperature and precipitation do not uniformly affect bee richness. Lower elevation protected areas are projected to experience mean losses of up to 5.8 species, whereas protected areas at higher elevations and transition zones may gain up to 7.8 species. Areas prioritized for future USSE development have an average species richness of 4.2 species higher than the study area average, and lower priority “variance” areas have 8.2 more species. USSE zones are expected to experience declines of up to 8.0 species by 2050 due to climate change alone. Despite the importance of solitary bees for pollination, their diversity is often overlooked in land management decisions. Our results show the utility of JSDMs for leveraging existing collection records to ease the inclusion of data‐limited insect species in land management decision‐making.
Global Terrestrial Water–Energy Coupling Across Scales
Authors: Mbabazi Deanroy , Sehgal Vinit , Mohanty Binayak P.
Published: November 2024

Terrestrial water–energy coupling (WEC), in the form of a non‐linear relationship between Soil Moisture (SM) and evaporative fraction (EF, ratio of actual and potential evapotranspiration), controls critical ecohydrological processes. We investigate and parameterize the evolution of global SM–EF coupling from the field to remote‐sensing (RS)‐pixel. The field‐scale EF and SM were obtained from eddy covariance (EC) and SM sensors at the global FLUXNET and Texas Water Observatory sites. RS‐pixel‐scale EF and SM estimates were obtained from Moderate‐resolution Imaging Spectroradiometer (MODIS) and Soil Moisture Active Passive (SMAP) sensors, respectively. We estimate the effective thresholds of the WEC regimes from both EC and satellite datasets to highlight the influence of sub‐pixel‐scale heterogeneity, and, scaling and observational constraints on the evolution of WEC regimes from the field to RS‐pixel scale. We argue that the changes in land surface conditions add a temporal variability in the critical thresholds of terrestrial WEC at RS pixel scale. We compare the critical WEC thresholds of the water‐ and energy‐limited regimes with a SM drydown‐based approach and highlight the similarities between both methods in partitioning dominant WEC regimes. EF and SM are strongly coupled in dryland arid and semi‐arid regions compared to humid climates. WEC regimes and thresholds have strong interseason variability due to dynamic interactions between soil, vegetation and atmosphere at the RS‐pixel scale. In contrast, field‐scale SM‐EF coupling is influenced predominantly by soil conditions and land‐use/management practices. Hence, future development of Earth‐system/Land‐surface models must account for the inter‐scale differences in the coupling between terrestrial water and energy fluxes representative of the ‘effective’ processes at large spatial scales.
Linking the Flow Regime of Papyrus‐Dominated Wetlands to Biologically Relevant Hydrologic Attributes
Authors: Oyarmoi Alem , Birkinshaw Stephen , Hewett Caspar J. M. , Fowler Hayley J.
Published: November 2024

The dominant plant species in many African wetlands is Cyperus papyrus. Its adaptation to saturated and low‐oxygen conditions and its dense structure and height provide breeding and feeding grounds for unique flora and fauna. As a keystone species adapted to local hydrology, the flooding regime of papyrus offers the full range of hydrologic conditions and events essential to ecosystem health. However, no study has attempted to link papyrus wetlands' flow regimes to their biologically relevant hydrologic attributes. This study assesses hydrologic alterations of a papyrus wetland's flow regime due to rice irrigation. We develop a conceptual ecological model linking papyrus to hydrologic attributes to determine the consequences of changed environmental flow components (EFCs) on papyrus as a habitat. We find that agricultural water management considerably alters the magnitude, duration, timing and rate of change of EFCs, which could affect productivity (seed dispersal, germination and establishment; rhizome spreading; papyrus distribution across transects; and dispersal of floating mats) in papyrus wetlands. However, the effect on the papyrus wetlands' natural pulsed regime is negligible when the ratio of irrigated area to catchment area is no greater than 1:150. Overall, a better understanding of the threats of water diversion for agriculture is made by linking papyrus' flow regimes to biologically relevant hydrologic attributes. Knowledge of the roles of the various EFCs could provide opportunities for conserving and protecting papyrus wetlands, especially for systems at risk of altered flows.
Redox Reactions of [RuIII(pic)3] (pic−=picolinate) with Sulfite in Aqueous Solution: Kinetic, and Mechanistic Studies
Authors: Impert Olga , Chatterjee Debabrata
Published: November 2024

The reaction of [RuIII(pic)3] (pic−=picolinate) and sulfite (SO32−) resulting in the formation of [RuII(pic)3] − and sulfate (SO42−) has been studied spectrophotometrically and kinetically in aqueous solution. The rate of the reaction studied by following the appearance of the MLCT (metal to ligand charge transfer) band of the [RuII(pic)3)]− complex at 466 nm was found to be first‐order in both the complex and sulfite concentrations. The values of the observed rate constant depend on the pH, since it controls the speciation of oxoanions of sulfur(IV)‐species viz. bisulfite (HSO3−) and sulfite (SO32−) in the pH range 3.8 to 8.3. The product of the reaction, sulfate was ascertained by LDI‐mass spectral analysis ofthe post‐reaction solution. The activation parameters (ΔH≠ =56±3 kJ mol−1 and ΔS≠= ‐179±9 J mol−1 K−1) corresponding to the reduction of [RuIII(pic)3] with SO32− supports the operation of an outer‐sphere electron transfer mechanism. The experimentally observed electron‐transfer rate constant (k=5.60 M−1s−1 at 25 °C) is found to be in good agreement with that of calculated (k12=4.75 M−1s−1) using Marcus cross‐reaction relationship for outer‐sphere electron‐transfer reactions. A working mechanism consistent with the spectral and kinetic data is proposed for the aforesaid electron transfer reaction.
Bi[Se‐(2‐Me2NC6H4)]3: Single Source Precursor for Preparing Pure‐Phase, 2‐Dimensional Bismuth Selenide Films
Authors: P. D. Dharsana , Bisht Sheetal Kathayat , Majumder Saptak , Mondal Dipanjana , Singha Pintu , Bolegave Gaurav G. , Kamble Vinayak B. , Venugopal Ajay
Published: November 2024

Chemical vapor deposition using molecular compounds is a salient method to achieve high‐quality, uniform films comprising two‐dimensional flakes. In this communication, we present the synthesis and characterization of analytically pure single crystals of Bi[Se‐(2‐Me2NC6H4)]3, used as a single source precursor to grow thin films of bismuth selenide. The structural and morphological studies of the films were performed using powder X‐ray diffraction, Raman spectroscopy, scanning, and transmission electron microscopy, revealing a pure phase stoichiometry with two‐dimensional flakes of quintuple layers grown on glass, Si, and sapphire substrates. The deposited films on the glass surface show a near‐ideal Bi to Se stoichiometry of 1.84 and exhibit an ambient temperature resistivity of 30 mΩ.cm. When unevenly illuminated with a laser of 532 nm wavelength, it shows a photo‐thermoelectric (PTE) voltage generation with a response time of 2 seconds and an estimated Seebeck coefficient value of −128±6.6 μV/K, thus demonstrating its suitability for device applications in IoTs.
Enhancing the efficiency of hydrokinetic Savonius turbine with guiding walls
Authors: Ayadi Ahmed , Rabeh Nour , Nasraoui Haytham , Mosbahi Mabrouk , Driss Zied
Published: November 2024

Hydropower offers a means of generating electricity through the conversion of water flow's mechanical energy using rotors. The helical Savonius rotor is recognized as one of the most commonly employed rotor types. An approach employed to boost power output involves the utilization of guiding walls, positioned upstream of the Savonius rotor. In this specific study, an investigation is presented into a helical Savonius rotor equipped with an innovative deflector design composed of guiding walls in the form of NACA‐profiled plates. Ansys Fluent is used to simulate the water flow around the helical Savonius turbine and the guiding walls. The geometric parameters of this design of guiding walls are adjusted to identify the most efficient configuration. When examining all considered configurations, an improvement is noted in the maximum power coefficient, with a significant increase compared with a conventional configuration. In fact, the power coefficient could be improved by 44% using optimal dimensions of the guiding walls. The inclusion of the proposed guiding walls in conjunction with the optimized geometric parameters emerges as a strategy to enhance the rotor's power coefficient.
Seismic Safety Evaluation of a Full‐Size Reinforced Concrete Frame Infilled With Precast Modular Reinforced Blocks Using Pseudo‐Dynamic Testing and Nonlinear Dynamic Finite Element Analysis
Authors: Jung Ju‐Seong , Lee Kang‐Seok
Published: November 2024

This study proposes a novel seismic retrofitting method involving a reinforced concrete (R/C) frame infilled with precast modular reinforced blocks (PMRBs) to address the limitations of conventional infilling techniques. The retrofitting system for the R/C frame infilled with PMRB maximizes the advantages of factory‐produced modular reinforcement blocks, considerably improving the constructability and joint integrity between the existing frame and the reinforcement, without substantially increasing the structural weight. Moreover, this approach uses a typical frame‐infilling method to enhance lateral load capacity, simplifying the calculation of the required amount of seismic reinforcement; thus, it is ideal for R/C buildings with non‐seismic detailing dominated by shear failure because it helps secure the necessary strength. A pseudo‐dynamic test was conducted using a full‐scale two‐story frame test specimen, based on an existing R/C building with non‐seismic detailing, to verify the restoring force characteristics, strength‐increasing effects, reinforcement strain and seismic response control capabilities of the PMRB frame‐infilling system. Nonlinear dynamic finite element analysis (FEA) was performed to compare and estimate the results of the pseudo‐dynamic test. The study results showed that the average deviation ratio for the seismic response load and displacement between the nonlinear dynamic FEA and the pseudo‐dynamic test was approximately 10%, indicating similar outcomes. Under a design basis earthquake of 200 cm/s2 in seismic intensity, the unreinforced R/C frame experienced shear failure, whereas the PMRB‐reinforced frame sustained only minor earthquake damage, even under seismic accelerations of a maximum considered earthquake of 300 cm/s2 and a large‐scale earthquake of 400 cm/s2. Thus, the newly developed PMRB frame‐infilling system shows great promise for seismic reinforcement.
The Lifetime Prevalence of Non‐Suicidal Self‐Injury in Children and Adolescents With Eating Disorders—A Systematic Review and Meta‐Analysis
Authors: Meier Marieke , Jansen Katrin , Vertgewall Hannah , Claes Laurence
Published: November 2024

Objective

Eating disorders (EDs) and non‐suicidal self‐injury (NSSI) are both phenomena with onset in adolescence. Their co‐occurrence is associated with higher symptom severity and an elevated risk of suicide. In this meta‐analysis, we examine the lifetime prevalence of NSSI in youth with EDs.

Methods

We searched PsycInfo, PubMed and previously published systematic reviews for studies reporting on lifetime NSSI prevalence among children and adolescents (19 years or younger) with an ED (anorexia nervosa, bulimia nervosa, binge eating or other specified feeding and EDs) published until June 2024. A generalized linear mixed model meta‐analysis was performed to estimate the pooled prevalence. Meta‐regressions and multivariate meta‐analyses were conducted to estimate separate prevalence rates based on ED diagnosis and care frame (e.g., inpatient vs. outpatient), respectively.

Results

Fifteen studies comprising 3311 children and adolescents were included. Pooled lifetime NSSI prevalence across all ED diagnoses was 34.2% [CI: 27.5%–41.7%]. Heterogeneity was large (I2 = 93.8%). Lifetime NSSI prevalence rates were significantly higher for participants with bulimia nervosa (53.6%) and those with anorexia nervosa binge‐eating/purging type (51.9%) than for participants with anorexia nervosa restrictive type (15.8%).

Discussion

The small number of studies and the large heterogeneity limit the conclusiveness of this meta‐analysis. Results suggest an even higher prevalence of lifetime NSSI in adolescents with an ED than in adults with an ED. The results support previous findings indicating higher prevalence rates of NSSI for EDs associated with binge eating and purging behaviours than for restrictive EDs.
Morphodynamics of anabranching structures in the Peruvian Amazon River
Authors: Abad Jorge D. , Garcia Adrian P. , Marín‐Díaz Jesus , Escobar Catalina , Ortals Collin , Chicchon Hernan
Published: November 2024

Along its 650‐km reach, the Peruvian Amazon River comprises anabranching structures, spanning from the confluence of the Marañón and Ucayali Rivers to the Peru–Brazil–Colombia border. Combining remote sensing techniques and field measurements, this research aims to understand the hydrogeomorphology of these anabranching structures. The multitemporal analysis every 5 years over 35 years (1985–2020) reports channel migration rates, erosion/deposition rates, angles of bifurcations and confluences, among other metrics including the number of channels, length, wavelength average, width and sinuosity, as well as the area, shape and number of islands for each structure. Fieldwork also included hydrodynamic measurements along the Peruvian Amazon River to characterize the flow structure and water fluxes. Results showed that the Peruvian Amazon River developed single (stable) and compound (unstable) anabranching structures at a spatial periodicity of about 22.4 km, with an average displacement speed of approximately 74 m/year. Compound anabranching structures were found at the inlet region (near the origin of the Amazon River) and where significant tributaries flow into the main river and water and sediment fluxes impose destabilizing boundary conditions.
Isotopic and Sedimentologic Proxies of Palaeoexposure Events and Oceanic Anoxic Event 2 (OAE2) in the Cenomanian–Turonian Neritic Carbonates (the Sarvak Formation) in the Abadan Plain, Zagros Basin, Iran
Authors: Yahyaei Emad , Mehrabi Hamzeh , Abbasi Ramin
Published: November 2024

The shallow marine carbonate deposits of the Sarvak Formation have been deposited in an active tectonic setting under warm and humid climatic conditions during the Cenomanian–Turonian (C–T). The focus of this study is on the sedimentological and geochemical analysis of this formation in the Abadan Plain, Zagros Basin. Petrographic studies led to the identification of five microfacies deposited in the restricted lagoon, tidal flat, reef, shoal and open marine environments. They indicate deposition of the Sarvak Formation on a homoclinal ramp–like carbonate platform. Sequence stratigraphy studies have led to the identification of two third‐order sequences named Cenomanian sequence (DSS‐1) and Turonian sequence (DSS‐2), along with six fourth‐order sequences. The upper boundary of DSS‐1, known as the C–T disconformity (CT‐ES), is subjected to meteoric diagenetic processes, as evidenced by meteoric dissolution (karstification), collapsed brecciation and the development of palaeosols. The upper SB of DSS‐2 is marked by the mid‐Turonian disconformity (mT‐ES), characterised by silicification, brecciation, meteoric dissolution and iron oxide staining of core samples. The significant decreases in δ18Ocarb and δ13Ccarb values indicate a strong effect of meteoric diagenesis beneath the palaeoexposure surfaces. The calculation of sea surface temperatures (SSTs) based on the δ18Ocarb values measured from the unaltered carbonates indicated that the average SST for the C–T is 31.8°C and 30.9°C in K‐01 and K‐02 wells, respectively. A decrease of about 1.5°C is measured during the C–T transition, which indicate a cooling trend of the Late Cretaceous in the Tethyan realm. The carbon isotopic pattern observed in the analysed sections shows correlation with previous studies conducted in the Tethyan region. Additionally, the isotopic composition indicative of Oceanic Anoxic Event 2 (OAE2) is identified around the C–T boundary. Nevertheless, the signature of OAE2 has been somewhat obscured by diagenetic processes associated with C–T palaeoexposure.
Cambrian–Ordovician Arc‐Related Magmatism in the Central Southeast Asian Continents and Its Significance on Early Palaeozoic Tectonics of the Indochina Block
Authors: Ngo Xuan Thanh , Hung Nguyen Quoc , Kim Yoonsup , Kwon Sanghoon , Bui Vinh Hau , Tran Thanh Hai , Jang Yirang , Samuel Vinod O.
Published: November 2024

Knowledge of the early Palaeozoic tectonic evolution of the Indochina Block is critical for reconstructions of the Gondwana supercontinent in relation with other microcontinents. In the central Indochina Block, the Early Palaeozoic Tam Ky–Phuoc Son Suture Zone (TPSZ) and Po Ko Suture Zone (PKSZ) demarcate the boundary between the Truong Son Belt in the north and Kon Tum Massif in the south. In the southern parts of Truong Son Belt, we have identified meta‐mafic and meta‐intermediate rocks associated with plagiogranite, metapelitic and meta‐siliceous rocks. Here we present integrated field, geochemical and geochronological results of the meta‐gabbroic and amphibolitic samples in the southern Truong Son Belt to unravel the tectonic evolution of the Indochina Block during the Early Palaeozoic. The MC–LA–ICP–MS zircon U–Pb ages indicate magmatism at ca. 504–460 Ma. Based on geochemical composition, the samples range from gabbro to gabbro‐diorite. The gabbroic samples have slightly higher Mg# (58.9–62.8) than those of the gabbro‐dioritic samples (Mg# = 56.3–61.5), and both types of rock show low TiO2 contents (0.68–0.98 wt%), displaying enriched LREE ((La/Sm)N = 1.66–3.23) and LILE (e.g., Rb, Ba, Th and U), and pronounced negative HFSE (e.g., Nb, Ta and Ti anomalies) with low εHf(t) zircon values (from −6.34 to +0.71). These geochemical characteristics suggest that the metabasic rocks are of subduction‐related arc magmatic processes, and also indicate infiltration of sediment melt from subducting slab to mantle‐wedge prior to its partial melting. The new data suggests that northward subduction under the Truong Son Belt might have initiated during the Early Cambrian, and lasted until around the Middle Ordovician. On a regional scale, the ages of the Early Palaeozoic arc magmatism in the Truong Son Belt are comparable with the ages of tectonic events that occurred in Himalaya, West Qiangtang and East Tibet at the northern margin of the Gondwana supercontinent.
Prognostic Role of Pretreatment Tumor Burden and Dissemination Features From 2‐[18F]FDG PET/CT in Advanced Mantle Cell Lymphoma
Authors: Albano Domenico , Bianchetti Nicola , Talin Anna , Dondi Francesco , Re Alessandro , Tucci Alessandra , Bertagna Francesco
Published: November 2024

Mantle cell lymphoma (MCL) is an aggressive non‐Hodgkin lymphoma with poor prognosis. The usefulness of fluorine‐18‐fluorodeoxyglucose positron emission tomography/computed tomography (2‐[18F]FDG PET/CT) and its parameters in the evaluation of treatment response and prognosis is not yet clear. The aim of this study was to investigate the prognostic role of tumor burden and tumor dissemination features derived by 2‐[18F]FDG PET/CT in advanced MCL. We retrospectively included 120 patients with advanced MCL who underwent baseline 2‐ 2‐[18F]FDG PET/CT and end‐of‐treatment (eot) PET/CT. The baseline‐PET images were analyzed visually and semi‐quantitatively by measuring the maximum standardized uptake value body weight (SUVbw), lean body mass (SUVlbm), body surface area (SUVbsa), metabolic tumor volume (MTV), total lesion glycolysis (TLG) and dissemination features (Dmax and Dmax‐bsa). EotPET/CT was judged according to the Lugano classification. Progression‐free survival (PFS) and overall survival (OS) were plotted according to the Kaplan–Meier method. At a median follow‐up of 59 months, relapse/progression occurred in 68 patients while death in 38 patients with a median PFS and OS of 27.2 and 57.6 months, respectively. MIPI score, Bulky disease, Ki‐67 index, metabolic response, pretreatment MTV and TLG were significantly associated with PFS at univariate analysis, but only metabolic response, MTV and TLG were confirmed to be independent prognostic factors. Considering OS, only dissemination features were demonstrated to be prognostic features. In conclusions, metabolic response and metabolic tumor burden parameters (MTV and TLG) are strongest predictor of PFS, while dissemination features may have a significant role for predicting OS.
Efficacy of chitosan powder in reducing vaginal bleeding following a loop electrosurgical excision procedure: A randomized control trial
Authors: Güngördük Kemal , Ünver Hikmet Can , Uyar Berican Şahin , Ergü Berke Nur , Gülseren Varol , Özdemir İsa Aykut
Published: November 2024

Objective

To evaluate the efficacy of topical chitosan powder in reducing postoperative vaginal bleeding following a loop electrosurgical excision procedure (LEEP).

Methods

In this randomized controlled trial, patients who underwent LEEP were randomly assigned (1:1) to the chitosan group, in which the wound area was sprayed with chitosan powder using a spray pump, or the control group. The primary outcome was the median quantity of vaginal blood lost in the early postoperative period (defined as within 6 h of the procedure).

Results

The 124 women enrolled in the study were randomly divided into control (n = 61) and chitosan (n = 63) groups. The median amount of vaginal blood loss during the early postoperative period was significantly lower in the chitosan group than in the control group (198.85 [64.4–388.57] mL vs. 250.60 [67.7–552.87] mL; P < 0.001). The rate of late postoperative bleeding requiring hemostatic intervention was also lower in the chitosan group than in the control group (3.2% vs. 16.4%; P = 0.013). Superior cervical wound healing in the chitosan group compared to the control group was also observed.

Conclusion

The application of chitosan powder to the cervical wound bed can improve surgical outcomes by decreasing post‐LEEP vaginal bleeding and facilitating the healing of cervical wounds.
The mitochondrial DNA copy number and ovary‐related reproductive disorders: A bidirectional two‐sample Mendelian randomization study
Authors: Peng Ke , Han Xiao , Wu Congquan , Lu Qiaowen , Gao Shujun
Published: November 2024

Objective

In the present study, a bidirectional two‐sample Mendelian randomization approach was utilized to explore potential causal relationships between mitochondrial DNA copy number (mtDNA‐CN) and ovary‐related reproductive disorders (ORRDs), including ovarian dysfunction, ovarian cyst, polycystic ovary syndrome (PCOS), premature ovarian failure (POF) and ovarian endometriosis.

Methods

Genetic associations with mtDNA‐CN were obtained from three genome‐wide association study (GWAS) summary statistics from the UK Biobank, and ORRD data were investigated using summary statistics from the FinnGen cohort. Single nucleotide polymorphisms (SNPs) correlated with mtDNA‐CN were selected as genetic instrumental variables (IVs) to estimate the causal effect of mtDNA‐CN on ORRDs using the inverse‐variance weighted (IVW) method with heterogeneity and pleiotropy analysis, and we repeated this in the opposite direction using instruments for ORRDs.

Results

We found that the genetically predicted mtDNA was indicative of increased levels of PCOS (OR = 1.16; P < 0.001) and ovarian endometriosis (OR = 1.25; P = 0.007) in the IVW analysis and was not associated with the risk of other ORRDs. In the reverse direction, genetically predicted ORRDs were not associated with mtDNA‐CN levels in the IVW analysis. Sensitivity and replication analyses showed the results to be stable.

Conclusion

We found that mtDNA‐CN may increase the risk of PCOS and ovarian endometriosis. This may have implications for mtDNA‐CN as a biomarker for these conditions in clinical practice.
Serial evaluation of morphological and biophysical placental attributes in women with normal outcome and preeclampsia
Authors: Kumar Manisha , Debnath Ekta , Malhotra Seema , Yadav Reena , Singh Shalini
Published: November 2024

Objective

The study's aim was to perform serial placental biometry and Doppler assessments in antenatal women and compare the characteristics of preeclampsia (PE) and normal outcome.

Methods

This prospective cohort study was carried out after ethical clearance. Placental length (PL), thickness, and plavental volume (PV), along with the uterine artery (Ut), middle cerebral artery (MCA), and umbilical artery (UA) blood flow were evaluated serially at 11–14, 20–24, and 28–32 weeks of gestation. The women were followed until delivery, those with PE were considered cases, and those with no other adverse outcome were controls. The placental attributes between cases and controls were compared.

Results

A total of 135/1008 (13.4%) had hypertensive disorders of pregnancy (HDP) and 44/1008 (4.4%) had PE, and no maternal or fetal adverse outcomes were seen in 600 (59.5%) women. The PL and PV were significantly less in those with PE (P = 0.005) than in controls. The ratios of PL/Ut A PI and PV/Ut A PI were significantly lower in cases than in controls in all trimesters (P <0.001). In the first trimester, the area under the curve (AUC), sensitivity, and specificity of PV/Ut A PI for PE prediction were 0.801, 81.8%, and 70.5%, respectively. The sensitivity and specificity of the PL/Ut PI ratio was 81.8% and 70.5%, whereas that at 28–32 weeks was 73.3% & 70.7%.

Conclusion

Placental parameters were significantly lower in PE than in normal outcome, and the ratios of PL/Ut A PI and PV/Ut A PI proved to be promising markers.
Importance of proteins and mitochondrial changes as freshness indicators in fish muscle post‐mortem
Authors: Hematyar Nima , Policar Tomas , Rustad Turid
Published: November 2024

Evaluating protein and mitochondrial alterations post‐mortem can contribute to determining correlations between fish‐processing parameters and ultimate fish muscle quality. The myofibrillar protein alteration during rigor mortis directly affects the texture of fish muscle. To identify the mechanisms behind post‐mortem softness and quality deterioration, it is crucial to understand the conditions linked to the breakdown of myofibrillar proteins in fish skeletal muscle. Therefore, monitoring protein breakdown at the molecular level and finding target proteins would be considered a marker for fish freshness. Mitochondria play an important role in executing and regulating cell death processes, including apoptosis and necrosis. The mitochondria are the seat of cellular respiration and experience significant alterations in post‐mortem tissues. Processes used to reduce protein degradation, such as optimizing chilling and handling practices, would also minimize mitochondrial changes in fillet quality. Moreover, pH fluctuations are considered a critical point that influences both protein and mitochondrial changes. This review considered the implications of protein and mitochondrial alteration during post‐mortem storage in fish fillets and the possible pathways of their interaction on fillet quality. Mitochondrial characteristics, such as membrane integrity, pH, and ATP levels, are important for post‐mortem muscle cell changes, serving as an early indicator of fish freshness. Understanding the mechanisms behind protein degradation in fish muscle led to maintaining fillet quality and requires further experiments. Label‐free proteomics combined with bioinformatics is crucial for comprehending protein degradation mechanisms to provide customers with safe and fresh fish products while minimizing economic losses associated with fillet deterioration. © 2024 The Author(s). Journal of the Science of Food and Agriculture published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.
Three‐Photon Upconversion Luminescence of Gd2O2S: Ho3+, Er3+ for High‐Sensitivity FIR Thermometer and Multimode Anti‐Counterfeiting
Authors: Shao Yuhe , Liu Hongzhen , Chen Mingyue , Song Zhen , Liu Quanlin
Published: November 2024

The performance control and multidimensional applications of upconversion phosphor have become the hotspot and difficulty in current research and application due to the complex luminescence mechanism. Based on the efficient Gd2O2S: Er3+ upconversion luminescence of 1550 nm excitation and design strategy for co‐doped materials, the multicolor (light green to red) and multifunctional upconversion phosphor Gd2O2S: Er3+, Ho3+ is successfully prepared. Benefiting from the clear mechanism of three‐photon upconversion and energy transfer after co‐doping, the novel applications of Gd2O2S: Er3+, Ho3+ can greatly be expanded. This phosphor can be well used as a fluorescence thermometer due to the higher sensitivity (2.46% K−1@170 K), wider temperature sensing range (170–267 K, Sr > 1% K−1), and greater color variation (Δx = 0.2416, Δy = 0.2483) relative to Gd2O2S: Er3+ and other same type of material. In addition, multiple patterns and encoded outputs are also effectively achieved by the combination of phosphors under multiple light stimuli response. This shows the greater application potential of phosphor in the fields of anti‐counterfeiting and information encryption. This study can also provide a new view to study the more high‐performance and multifunctional upconversion phosphor.
Harnessing Nature‐Derived Sustainable Materials for Electrochemical Energy Storage: Unveiling the Mechanism and Applications
Authors: Sharma Naman , Mishra Kirti , Singh Nirankar , Siwal Samarjeet Singh , Hart Phil , Thakur Vijay Kumar
Published: November 2024

Recently, research all over the world is being carried out to develop eco‐friendly supercapacitors (SCs) using biopolymeric materials like proteins or polysaccharides. These polymers offer these innovative energy storage devices' sustainability and recyclability, flexibility, lightweight, and steady cycling performance—all crucial for utilizations involving wearable electronics and others. Given its abundance and extensive recycling behavior, cellulose is one of the most sustainable natural polymers requiring special attention. The paper discusses the various types of cellulose‐based materials (CBMs), including nanocellulose, cellulose derivatives, and composites, as well as their synthesis methods and electrochemical properties. The review also highlights the performance of CBMs in SC applications, including their capacitance, cycling stability, and rate capability, along with recent advances in modifying the materials, such as surface modification and hybrid materials. Finally, the proposed topic is concluded with the current challenges and future prospects of CBMs for SC applications.
The Effect of Reprocessing and Moisture on Polyamide Recycling: A Focus on Neat, Composites, and Blends
Authors: Morales Johanna , Rodrigue Denis
Published: November 2024

Polyamides (PA), commercially known as Nylon, are versatile engineering thermoplastics extensively used in different industries due to their thermal, and chemical resistance and excellent mechanical properties. Although polyamide recycling has received significant attention due to increasing demand for sustainable practices, it is important to understand the effect of the different factors involved in the mechanical recycling of this polymer. The initial part of this review presents an overview of the PA in the industry, its classification, properties, and applications. Following this, the effects of reprocessing cycles are examined, concluding with the impact of moisture before and after the recycling of polyamides. This review not only focuses on the recycling of PA 6 and PA 66 but also includes other grades, such as PA 11 and PA 12. Additionally, it covers the recycling of PA blends and composites.