bluuebunny/crossref_metadata_2025 huggingface dataset:
Biomarcadores radiológicos en RM para una aproximación al diagnóstico molecular en gliomas IDH-mutados (grado II y III)
Authors: Darakdjian Maximiliano , Osa Sanz Emilia , Hernández Pinzón Jairo , Carnevale Martín , Diebel Alfonsina , Arakaki Naomi , Martinetto Horacio Enrique , Sevlever Gustavo , Yáñez Paulina
Published: December 2020

Objetivo Analizar características por resonancia magnética (RM) de gliomas IDH-mutados (grado II y III) en base a parámetros cualitativos, a fin de valorar el rendimiento del signo del mismatch T2-FLAIR y otras características morfológicas de los tumores, en predecir el estado del 1p/19q y su reproducibilidad interobservador.

Métodos Estudio retrospectivo, descriptivo y analítico sobre una cohorte de 53 gliomas IDH-mutados (grado II y III) y molecularmente definidos respecto al 1p/19q, seleccionados a partir de la base de datos de la institución, durante el periodo 2014–2019. Dos neuroradiólogos evaluaron características imagenológicas de forma independiente y enmascarada al diagnóstico: mismatch T2-FLAIR, localización tumoral, bordes, señal, infiltración cortical e inhomogeneidad en T2*. Los casos discordantes fueron evaluados por un tercer neuroradiólogo de mayor experiencia.

Resultados Treinta de 53 (56,6%) gliomas fueron no codelecionados, y 23/53 (43,4%) codelecionados. El signo del mismatch T2-FLAIR fue positivo en 16/53 (30,18%) pacientes, 15/16 (93,75%) no codelecionados y 1/16 (6,25%) codelecionado (Exacto de Fisher p= <,0001). Los dos evaluadores demostraron una concordancia interobservador casi perfecta para ese signo, κ =,907 (95% CI, 0,781 a 1,0). La especificidad y el valor predictivo positivo del signo para predecir la ausencia de la codeleción fue de un 95,7% y un 93,8% respectivamente.

Discusión La reciente actualización en la clasificación de los gliomas los clasifica acorde a su perfil molecular. En los últimos años, varios investigadores han estudiado características morfológicas por RM de los tumores con la intención de predecir las características moleculares de los mismos.

Conclusión En nuestra población, el signo del mismatch T2-FLAIR es el único biomarcador radiológico que muestra asociación estadísticamente significativa en predecir la ausencia de codeleción en los gliomas IDH-mutados (grado II y III), con una alta especificidad y un alto valor predictivo positivo.
Research Trends in Anticoagulation Therapy over the Last 25 Years
Authors: Mian Mustafa K. , Sreedharan Subhashaan , Limaye Neeraj S. , Hogan Chris , Darvall Jai N.
Published: December 2020

A large volume of literature has become available to practitioners prescribing anticoagulants. The aim of this study was to analyze the bibliometric characteristics of the top 100 most cited articles related to anticoagulation over the past 25 years, with special consideration to impact of direct or “nonvitamin K antagonist” oral anticoagulants (NOACs) compared with vitamin K antagonists. A bibliometric analysis of the 100 most cited journal articles related to anticoagulants published between 1994 and 2019 was performed in April 2019. The top 100 articles by citation count were analyzed to extract bibliometric data related to journal title, impact factor, year of publication, place of publication, anticoagulant studied, indication for anticoagulation, study design, and conflicts of interest. The median (interquartile range) number of citations per article was 806 (621–1,085). The anticoagulant most frequently researched was warfarin (37%). NOAC publications (21%) grew at a relative rate of 3.4 times faster compared with all publications. The indication most commonly researched was venous thromboembolism (26%). Eighty articles constituted level I or II evidence, with randomized controlled trials the most common type of study (74). A financial conflict of interest was declared in 87% of articles with private, for-profit organizations the most common source of funding (26%). In summary, top research related to anticoagulation is highly impactful but may be at risk of sponsorship bias. High-level evidence for NOACs continues to expand across a range of indications with citation metrics likely to soon approach or surpass that of older drugs.
‘We’re definitely that link’: the role of school-based primary health care registered nurses in a rural community
Authors: Sanford Catherine , Saurman Emily , Dennis Sarah , Lyle David
Published: December 2020

Children and adolescents in rural Australia experience poorer health and educational outcomes than those in urban areas. This paper presents findings from a qualitative study exploring the role of primary health care registered nurses (RNs) working in the School-Based Primary Health Care Service in Broken Hill, far west New South Wales. The Service integrates health district-employed RNs with school learning and support teams to increase service access and improve health and education outcomes for students. The findings show that RNs used care navigation to reduce barriers to care by addressing healthcare candidacy with students and families. The RNs also linked schools, families and health and social care services, and facilitated intersectoral collaboration to improve the support provided to students experiencing health and developmental issues. Integrating health district-employed RNs with existing student support services is a promising approach to improving the health and education of disadvantaged students. This study provides individual- and system-level explanations of the role of the school-based primary health care RN and can inform the development of similar services elsewhere.
Proton strings and rings in atypical nucleation of ferroelectricity in ice
Authors: Lasave J. , Koval S. , Laio A. , Tosatti E.
Published: December 2020

Significance

In pure crystalline ice, the ferroelectric (FE) low-temperature state expected from the third law of thermodynamics is famously elusive, an anomaly which even led researchers to hunt, unsuccessfully, for fossil FE ice in frozen Antarctica. Experimentally, reaching FE ice usually needs dopants such as metal hydroxide KOH. Theoretically, ice rule constraints historically defied attempts to simulate and understand the FE evolution of both clean and doped bulk ice. Adequate Monte Carlo strategies applied to a lattice model inclusive of ice rules and dipole–dipole interactions overcome these difficulties, demonstrating both the equilibrium FE transition of clean ice and the singular FE nucleation by dopant-originated proton strings, which compare successfully with the slow and incomplete FE evolution observed by neutron diffraction.
Molecular Opacity Calculations for Lithium Hydride at Low Temperature
Authors: Liang Gui-Ying , Peng Yi-Geng , Li Rui , Wu Yong , Wang Jian-Guo
Published: December 2020

The opacities of the lithium hydride molecule are calculated for temperatures of 300 K, 1000 K, 1500 K, and 2000 K, at a pressure of 10 atm, in which the contributions from the five low-lying electronic states are considered. The ab initio multi-reference single and double excitation configuration interaction (MRDCI) method is applied to compute the potential energy curves (PECs) of the 7LiH, including four 1
Σ
+ states and one 1
Π state, as well as the corresponding transition dipole moments between these states. The ro-vibrational energy levels are calculated based on the PECs obtained, together with the spectroscopic constants. In addition, the partition functions are also computed, and are provided at temperatures ranging from 10 K to 2000 K for 7LiH, 7LiD, 6LiH, and 6LiD.
Extreme Ultraviolet Frequency Comb with More than 100 μW Average Power below 100nm
Authors: Zhang Jin , Hua Lin-Qiang , Chen Zhong , Zhu Mu-Feng , Gong Cheng , Liu Xiao-Jun
Published: December 2020

Extreme ultraviolet (XUV) frequency comb is a powerful tool in precision measurement. It also brings many new opportunities to the field of strong field physics since high harmonic generation related phenomena can be studied with high repetition rate. We demonstrate the generation of an XUV frequency comb with the aid of intra-cavity high harmonic generation process. The setup is driven by a high power infrared frequency comb, and an average power of 4.5 kW is reached in the femtosecond enhancement cavity. With Xe gas as the working media, harmonics up to the 19th order are observed. Power measurement indicates that as much as 115.9 μW (1.3 mW) are generated at ∼94 nm (∼148 nm). The shortest wavelength we can reach is ∼55 nm. The coherence of the generated light is tested with an optical-heterodyne-based measurement of the third harmonic. The resulted line width is ∼3 Hz. In addition, with this system, we also observe a strong suppression of below threshold harmonics from O2 compared to that from Xe. These results suggest that the current system is ready for precision spectroscopic measurements with few-electron atomic and molecular systems in XUV region as well as the study of strong field physics with an unprecedented 100MHz repetition rate.
Cutting out the cosmological middle man: general relativity in the light-cone coordinates
Authors: Mitsou Ermis , Fanizza Giuseppe , Grimm Nastassia , Yoo Jaiyul
Published: December 2020

Analytical computations in relativistic cosmology can be split into two sets: time evolution relating the initial conditions to the observer’s light-cone and light propagation to obtain observables. Cosmological perturbation theory in the Friedmann–Lemaître–Robertson–Walker (FLRW) coordinates constitutes an efficient tool for the former task, but the latter is dramatically simpler in light-cone-adapted coordinates that trivialize the light rays toward the observer world-line. Here we point out that time evolution and observable reconstruction can be combined into a single computation that relates directly initial conditions to observables. This is possible if one works uniquely in such light-cone coordinates, thus completely bypassing the FLRW ‘middle-man’ coordinates. We first present in detail these light-cone coordinates, extending and generalizing the presently available material in the literature, and construct a particularly convenient subset for cosmological perturbation theory. We then express the Einstein and energy–momentum conservation equations in these coordinates at the fully non-linear level. This is achieved through a careful 2 + 1 + 1 decomposition which leads to relatively compact expressions and provides good control over the geometrical interpretation of the involved quantities. Finally, we consider cosmological perturbation theory to linear order, paying attention to the remaining gauge symmetries and consistently obtaining gauge-invariant equations. Moreover, we show that it is possible to implement statistical homogeneity on stochastic fluctuations, despite the fact that the coordinate system privileges the observer world-line.
Tracing the ionic evolution during ILG induced phase transformation in strontium cobaltite thin films
Authors: Gao Lei , Chen Xiaokun , Lyu Xiangyu , Ji Guiping , Chen Zhanfen , Zhu Mingtong , Cao Xun , Li Chaorong , Ji Ailing , Cao Zexian , Lu Nianpeng
Published: December 2020

Ionic liquid gating (ILG) that drives the ions incorporate into or extract from the crystal lattice, has emerged as a new pathway to design materials. Although many intriguing emergent phenomena, novel physical properties and functionalities have been obtained, the gating mechanism governing the ion and charge transport remains unexplored. Here, by using the model system of brownmillerite SrCoO2.5 and the corresponding electric-field controlled tri-state phase transformation among the pristine SrCoO2.5, hydrogenated HSrCoO2.5 and oxidized perovskite SrCoO3−δ
through the dual ion switch, the ionic diffusion and electronic transport processes were carefully investigated. Through controlling gating experiment by design, we find out that the collaborative interaction between charge transport and ion diffusion plays an essential role to prompt the hydrogen or oxygen ions incorporate into the crystal lattice of SrCoO2.5, and therefore leading to formation of new phases. At region closer to the electrode, the electron can shuttle more readily in (out) the material, correspondingly the incorporation of hydrogen (oxygen) ions and phase transformation is largely affiliated. With the compensated charge of electron as well as the reaction front gradually moving away from the electrode, the new phases would be developed successively across the entire thin film. This result unveils the underlying mechanism in the electric-field control of ionic incorporation and extraction, and therefore provides important strategy to achieve high efficient design of material functionalities in complex oxide materials.
An autoencoder with adaptive transfer learning for intelligent fault diagnosis of rotating machinery
Authors: Tang Zhi , Bo Lin , Liu Xiaofeng , Wei Daiping
Published: December 2020

Under variable working conditions, a problem arises, which is that it is difficult to obtain enough labeled data; to address this problem, an adaptive transfer autoencoder (ATAE) is established to diagnose faults in rotating machinery. First, a data adaptation module, which calculates the maximum mean discrepancy for the network hidden-layer data in reproducing kernel Hilbert space, is introduced to the autoencoder network, thus making the classification model operate under variable working conditions. Variation particle-swarm optimization is then invoked to optimize the data adaptation parameters. Finally, the k-nearest neighbors algorithm, as the classification layer of the network, identifies the state of health of the rotating machinery. The capabilities of the intelligent fault-diagnosis network are verified using vibration signals from a bearing test rig and a gearbox test rig. The experimental results suggest that, compared with state-of-the-art diagnosis methods, the proposed ATAE network can significantly boost diagnostic performance in the absence of target vibration signal labels.
Analysis of the nonperfused volume ratio of adenomyosis from MRI images based on fewshot learning
Authors: Li Jiaqi , Wang Wei , Liao Lejian , Liu Xin
Published: December 2020

The nonperfused volume (NPV) ratio is the key to the success of high intensity focused ultrasound (HIFU) ablation treatment of adenomyosis. However, there are no qualitative interpretation standards for predicting the NPV ratio of adenomyosis using magnetic resonance imaging (MRI) before HIFU ablation treatment, which leading to inter-reader variability. Convolutional neural networks (CNNs) have achieved state-of-the-art performance in the automatic disease diagnosis of MRI. Since the use of HIFU to treat adenomyosis is a novel treatment, there is not enough MRI data to support CNNs. We proposed a novel few-shot learning framework that extends CNNs to predict NPV ratio of HIFU ablation treatment for adenomyosis. We collected a dataset from 208 patients with adenomyosis who underwent MRI examination before and after HIFU treatment. Our proposed method was trained and evaluated by fourfold cross validation. This framework obtained sensitivity of 85.6%, 89.6% and 92.8% at 0.799, 0.980 and 1.180 FPs per patient. In the receiver operating characteristics analysis for NPV ratio of adenomyosis, our proposed method received the area under the curve of 0.8233, 0.8289, 0.8412, 0.8319, 0.7010, 0.7637, 0.8375, 0.8219, 0.8207, 0.9812 for the classifications of NPV ratio interval [0%–10%), [10%–20%), …, [90%–100%], respectively. The present study demonstrated that few-shot learning on NPV ratio prediction of HIFU ablation treatment for adenomyosis may contribute to the selection of eligible patients and the pre-judgment of clinical efficacy.
Estimating the biological effects of helium, carbon, oxygen, and neon ion beams using 3D silicon microdosimeters
Authors: Lee Sung Hyun , Mizushima Kota , Kohno Ryosuke , Iwata Yoshiyuki , Yonai Shunsuke , Shirai Toshiyuki , Pan Vladimir A , Bolst David , Tran Linh T , Rosenfeld Anatoly B , Suzuki Masao , Inaniwa Taku
Published: December 2020

In this study, the survival fraction (SF) and relative biological effectiveness (RBE) of pancreatic cancer cells exposed to spread-out Bragg peak helium, carbon, oxygen, and neon ion beams are estimated from the measured microdosimetric spectra using a microdosimeter and the application of the microdosimetric kinetic (MK) model. To measure the microdosimetric spectra, a 3D mushroom silicon-on-insulator microdosimeter connected to low noise readout electronics (MicroPlus probe) was used. The parameters of the MK model were determined for pancreatic cancer cells such that the calculated SFs reproduced previously reported in vitro SF data. For a cuboid target of 10 × 10 × 6 cm3, treatment plans of helium, carbon, oxygen, and neon ion beams were designed using in-house treatment planning software (TPS) to achieve a 10% SF of pancreatic cancer cells throughout the target. The physical doses and microdosimetric spectra of the planned fields were measured at different depths in polymethyl methacrylate phantoms. The biological effects, such as SF, RBE, and RBE-weighted dose at different depths along the fields were predicted from the measurements. The predicted SFs at the target region were generally in good agreement with the planned SF from the TPS in most cases.
Enhanced on-state current and suppressed ambipolarity in germanium-source dual vertical-channel TFET
Authors: Chahardah Cherik Iman , Mohammadi Saeed
Published: December 2020

In this paper, we provide a solution for the main disadvantages of tunnel field effect transistors (TFETs) by presenting a germanium-source dual vertical-channel TFET. Our device is composed of two Ge/Si tunneling junctions in which charge carriers tunnel perpendicular to the gate, and two n+ epi-Si layers which serve as two vertical conduction channels. Owing to the recessed gate architecture and overlap of the gate with source and drain regions, we remarkably increase the on-state current and suppress the ambipolar conduction. A calibrated Atlas device simulator is employed to investigate the device performance, and the simulation results show a dramatic drive current value of about 300 µA µm−1 and on-state to off-state current ratio of about 7 × 109. Moreover, our TFET yields a minimum subthreshold swing of 5.9 mV dec−1, and a sub 60 mV dec−1 subthreshold swing over six decades of drain current at 0.5 V operating voltage.
Brain network dynamics fingerprints are resilient to data heterogeneity
Authors: Menara Tommaso , Lisi Giuseppe , Pasqualetti Fabio , Cortese Aurelio
Published: December 2020

Context. Large multi-site neuroimaging datasets have significantly advanced our quest to understand brain-behavior relationships and to develop biomarkers of psychiatric and neurodegenerative disorders. Yet, such data collections come at a cost, as the inevitable differences across samples may lead to biased or erroneous conclusions. Objective. We aim to validate the estimation of individual brain network dynamics fingerprints and appraise sources of variability in large resting-state functional magnetic resonance imaging (rs-fMRI) datasets by providing a novel point of view based on data-driven dynamical models. Approach. Previous work has investigated this critical issue in terms of effects on static measures, such as functional connectivity and brain parcellations. Here, we utilize dynamical models (hidden Markov models—HMM) to examine how diverse scanning factors in multi-site fMRI recordings affect our ability to infer the brain’s spatiotemporal wandering between large-scale networks of activity. Specifically, we leverage a stable HMM trained on the Human Connectome Project (homogeneous) dataset, which we then apply to an heterogeneous dataset of traveling subjects scanned under a multitude of conditions. Main Results. Building upon this premise, we first replicate previous work on the emergence of non-random sequences of brain states. We next highlight how these time-varying brain activity patterns are robust subject-specific fingerprints. Finally, we suggest these fingerprints may be used to assess which scanning factors induce high variability in the data. Significance. These results demonstrate that we can (i) use large scale dataset to train models that can be then used to interrogate subject-specific data, (ii) recover the unique trajectories of brain activity changes in each individual, but also (iii) urge caution as our ability to infer such patterns is affected by how, where and when we do so.
Multiscale multivariate transfer entropy and application to functional corticocortical coupling
Authors: Zhang Yuanyuan , Chen Xiaoling , Pang Xiaohui , Cheng Shengcui , Li Xiaoli , Xie Ping
Published: December 2020

Objective. Complex biological systems consist of multi-level mechanism in terms of within- and cross-subsystems correlations, and they are primarily manifested in terms of connectivity, multiscale properties, and nonlinearity. Existing studies have each only explored one aspect of the functional corticocortical coupling (FCCC), which has some limitations in portraying the complexity of multivariable systems. The present study investigated the direct interactions of brain networks at multiple time scales.Approach. We extended the multivariate transfer entropy (MuTE) method and proposed a novel method, named multiscale multivariate transfer entropy (MSMVTE), to explore the direct interactions of brain networks across multiple time scale. To verify this aim, we introduced three simulation models and compared them with multiscale transfer entropy (MSTE) and MuTE methods. We then applied MSMVTE method to analyze FCCC during a unilateral right-hand steady-state force task.Main results. Simulation results showed that the MSMVTE method, compared with MSTE and MuTE methods, better detected direct interactions and avoid the spurious effects of indirect relationships. Further analysis of experimental data showed that the connectivity from left premotor/sensorimotor cortex to right premotor/sensorimotor cortex was significantly higher than that of opposite directionality. Furthermore, the connectivities from central motor areas to both sides of premotor/sensorimotor areas were higher than those of opposite directionalities. Additionally, the maximum coupling strength was found to occur at a specific scale (3–10).Significance. Simulation results confirmed the effectiveness of the MSMVTE method to describe direct relationships and multiscale characteristics in complex systems. The enhancement of FCCC reflects the interaction of more extended activation in cortical motor regions. Additionally, the neurodynamic process of brain depends not only on emergent behavior at small scales, but also on the constraining effects of the activity at large scales. Taken together, our findings provide a basis for better understanding dynamics in brain networks.
Overview of the ICRF antenna coupling experiments on EAST
Authors: Yang H. , Zhang X.J. , Qin C.M. , Zhao Y.P. , Yuan S. , Mao Y.Z. , Yang X. , Li M.H. , Urbanczyk G. , Wang M. , Wang X.J. , Xu H.D. , Ding B.J. , Li Y.C. , Xu G.S. , Hu L.Q. , Ai L. , Guo Y.Y.
Published: December 2020

Experimental verification of ion cyclotron range of frequencies (ICRF) wave coupling is crucial to gain insight into the physics of the improvement of ICRF antenna coupling. The progress of ICRF antenna coupling experiments on EAST has been reported since 2007. The dependence of the loading resistance on the target plasma parameters, operational regimes and synergic heating scenarios on EAST are reviewed. Results show that the antenna coupling resistance R
c in L-mode regime meets the relation of R
c ∝ exp(−1.5k
∥
x
c), which is in good agreement with the simulation results with a perfectly matched layer method, where k
∥ is the dominant launched parallel wave number and x
c is the distance of the ICRF antenna and fast wave cut-off layer. Low plasma current, gas puff in the magnetic connections with the ICRF antenna and lower hybrid wave/electron cyclotron heating are beneficial for improving ICRF antenna coupling. The antenna coupling has a strong response during large edge-localized modes (ELMs) but it becomes steady state during ELM free. The study of ICRF antenna coupling under various parameters is helpful to optimize the ICRF wave heating scenario and understand the physical mechanisms which influence the ICRF wave coupling in plasmas.
A new anomaly observed in 4He supporting the existence of the hypothetical X17 particle
Authors: Krasznahorkay A. J. , Csatlós M. , Csige L. , Gulyás J. , Koszta M. , Szihalmi B. , Timár J. , Firak D.S. , Nagy Á. , Sas N.J. , Krasznahorkay A.
Published: December 2020

Recently, we observed an anomalous peak-like excess of internal e+e− pairs at around 140° for the M1 transition depopulating the 18.15 MeV isoscalar 1+ state in 8Be. The deviation from the theoretical prediction can be described by GEANT simulations assuming the creation and subsequent decay of a new, light boson with a mass of 16.7 MeV/c2. In order to reduce the possible systematic errors from the experimenntal data, we re-investigated the 8Be anomaly with an improved setup and confirmed the anomaly within the statistical uncertainties. We also studied the angular correlation of the electron-positron pairs created in the M0 transition depopulating the 21.01 MeV 0− state in 4He, and observed an anomalous excess of e+e− pairs at a significantly smaller angle of 115°. Since the transition energy was higher in this case, the observed anomaly could be described by assuming the creation and subsequent decay of the same light particle in the simulations.
Exploiting electron parity violation: from Standard Model tests to dark matter detection predictions
Authors: Moreno O. , Donnelly T. W.
Published: December 2020

There has been recent interest in low energy, high luminosity polarized electron beams for studies of parity-violating (PV) electron scattering, such as the MESA accelerator at Mainz or an upgraded FEL facility at Jefferson Lab. Accurate measurements of the PV asymmetry in elastic electron scattering from nuclei can be used to determine Standard Model couplings, such as the weak-mixing angle or higher-order radiative corrections, as well as to extract specific information on the nuclear and nucleon structure. To this end, low uncertainties are required from modelling some confounding nuclear and nuclear structure effects, including isospin mixing, nucleon strangeness content or Coulomb distortion of electron wave functions. We estimate the sizes and theoretical uncertainties of such effects for a carbon 12 target. An experimental precision in the PV asymmetry of a few tenths of a percent may be reachable under certain kinematic conditions, that are also discussed for the same nuclear target.

This high precision PV asymmetry in elastic electron scattering can also be used to relate in a very simple manner the elastic electron-nucleus scattering cross section with the elastic neutrino-nucleus cross section. This novel relationship allows us to exploit experimentally well-determined quantities to predict unknown or recently measured observables, such as coherent neutrino-nucleus cross sections. This idea can be extended to link electron scattering to an even more uncertain magnitude: the direct detection rate of hypothetical weak-interacting dark matter particles through axial and/or vector elastic interactions with nuclei.
Heavy-flavour observables in relativistic nuclear collisions: theory overview
Authors: Beraudo Andrea
Published: December 2020

Transport calculations represent the major tool to simulate the modifications induced by the presence of a hot-deconfined medium on the production of heavy-flavour particles in high-energy nuclear collisions. After a brief description of the approach and of the major achievements in its phenomenological applications we discuss some recent developments. From the theory side we focus on the evaluation of transport coefficients and on recent formulations of the problem of heavy-flavour in-medium propagation in the language of open quantum systems. From a more phenomenological perspective we give an overview of the attempts to extend theoretical models to reproduce recent experimental data arising from event-by-event fluctuations (odd flow harmonics, event-shape-engineering) or from medium-modifications of hadronization (Ds
and Ac
production).
Transport properties of Heavy Quarks: anisotropic flows υn
and their correlations to the bulk dynamics and initial Electromagnetic field
Authors: Plumari Salvatore , Coci Gabriele , Minissale Vincenzo , Das Santosh K. , Oliva Lucia , Sambataro Maria Lucia , Greco Vincenzo
Published: December 2020

We study the correlations between light flavor and heavy quarks (HQs) flow harmonics at LHC energy within a transport approach. We have investigated the role of transport coefficient in developing these anisotropic flows correlations. We suggest

υ
n

h
e
a
v
y

−

υ
n

l
i
g
h
t

correlation and the relative fluctuations of anisotropic flows συη

/〈υn
〉 as novel observables to constrain the HQ transport coefficients in quark gluon plasma. Finally, very strong electro-magnetic (E.M.) fields are created in Ultra-relativistic Heavy-Ion Collision (HIC). We show within relativistic Boltzmann transport approach coupled with E.M. field that the strong e.m. field is responsible for a splitting of directed flow υ
1 of D and anti-D mesons of few percent, i.e. much larger compared to the observed charged particles. Moreover, we discuss the role played by the initial large bulk vorticity on the build up of rapidity odd HQs directed flow υ
1.
Major Accelerator Facilities for Nuclear Physics in Asia Pacific
Authors: Tanaka Kazuhiro
Published: December 2020

Asian Nuclear Physics Association (ANPhA) is the central organization representing nuclear physics in Asia Pacific. ANPhA is now preparing a list of accelerators applicable for nuclear physics experiments in Asia Pacific. Among the listed facilities, world-class “major” accelerator facilities are mainly located in China (Heavy Ion Research Facility in Lanzhou (HIRFL), and its future extension in Huizhou, i.e. HIAF/CiADS, Beijing Tandem Accelerator National Laboratory (BTANL), which is now upgraded to Beijing RI beam Facility (BRIF), in India (Variable Energy Cyclotron Centre (VECC) in Kolkata), in Korea (RISP/rAoN), and in Japan (RIBF at Riken, J-PARC, RCNP, and ELPH/LEPS). World class facilities based on the tandem accelerator are locating at Mumbai and New Deli in India, at Tokai-mura in Japan, and at Canberra in Australia. Characteristics of these “majof” facilities including their facility developments will briefly be reviewed in comparing with similar facilities in Europe and North America.
Low-energy studies for Nuclear Astrophysics (both above- and underground)
Authors: Bruno Carlo G.
Published: December 2020

Experimental investigation of nuclear properties of interest in low-energy pose astrophysical scenarios such as quiescent burning stars and classical novae face interesting challenges. Cross-sections are often too low for measurement on the surface of the Earth, and short-lived radioactive elements play a key role in a number stellar scenarios. In this short review, I will mention two experimental approaches to this challenge, namely the possibility to carry out measurements underground at the LUNA accelerator (LNGS, Italy) and a novel approach that employs storage rings pioneered at GSI Laboratory (Germany).
New investigations on the 32S(3He,d)33Cl reaction at 9.6 MeV bombarding energy
Authors: Cinausero M. , Dell’Aquila D. , Lombardo I. , Vigilante M. , Barlini S. , Bolzonella R. , Bruno M. , Buccola A. , Carturan S. M. , Casini G. , Cicerchia M. , D’Andrea M. , Degerlier M. , Fabris D. , Gasques L. , Gramegna F. , Lepine-Szily A. , Mantovani G. , Marchi T. , Piantelli S. , Rigato V. , Scomparin L. , Valdrè S.
Published: December 2020

The 32S(3He,d)33Cl one-proton transfer reaction is a powerful tool to investigate the spectroscopy of low-lying states in the proton-rich 33Cl nucleus. However, the extraction of firm differential cross-section data at various angles to benchmark and constrain theoretical models is made challenging by the presence of competitive reactions on target contaminants. In this paper we report on a recent measurement using a new generation hodoscope of silicon detectors, capable to detect and identify emitted deuterons down to energies of the order of 2 MeV. The high angular segmentation of our hodoscope combined with a suitable target to control possible contaminants, allowed to unambiguously disentangle the contribution of various states in 33Cl, in particular the 2.352 MeV state lying just few tens of keV above the proton separation energy.
Study of the contribution of the 7Be(d, p) reaction to the 7Li problem in the Big-Bang Nucleosynthesis
Authors: Inoue Azusa , Tamii Atsushi , Chan Phaikying , Hayakawa Seiya , Kobayashi Nobuyuki , Maeda Yukie , Nonaka Kotaro , Shima Tatsushi , Shimizu Hideki , Tran Dinh Trong , Wang Xuan , Yamaguchi Hidetoshi , Yang Lei , Yang Zaihong
Published: December 2020

Our research goal is to measure the cross section of the 7Be(d, p) reaction to find a solution for the cosmological the 7Li problem, which is an overestimation of the primordial 7Li abundance in the standard Big-Bang nucleosynthesis (BBN) model. We developed a method to produce an unstable 7Be target to measure the reaction in normal kinematics in a high-resolution measurement. We performed an experiment to produce the 7Be target and also to measure the cross section of the 7Be(d, p)8Be reaction with the produced 7Be target at the tandem facility, Kobe University. A 2.36 MeV proton beam irradiated a Li target to transmute 7Li particles to 7Be particles via the 7Li(p, n)7Be reaction. We produced 2.6×1013 7Be particles in the target after two days’ proton irradiation. After the target production, the beam ion was changed to deuterons with energies of 0.6, 1.0, and 1.6 MeV to measure the 7Be(d, p) reaction. The outgoing protons were measured by two ΔE-E silicon telescopes placed at 30° and 45°. We report the preliminary results of this experiment, including the 7Be(d, p) cross section.
A New Approach to Determine the 120(α,γ)16O Reaction Rate at Astrophysical Energies
Authors: Friščić Ivica , William Donnelly T. , Milner Richard G.
Published: December 2020

The ∼100% uncertainty in the measured rate of the 12C(α,γ)16O reaction at low energies (

E
α

c
m

⩽
1
MeV

) is the largest source of uncertainty in any stellar evolution model. With development of new, high-current, energy-recovery linear accelerators (ERLs) and high density gas targets, measurement of the 16O(e, e′α)12C reaction close to threshold using detailed balance opens up a new approach to determine the 12C(α,γ)16O reaction rate with increased precision (< 20%). We have considered the optimal design of an experiment where systematic uncertainties are minimized. Once the new ERLs commence operation near their design specifications, an experiment to validate the new approach we propose should be carried out. Our method has broad applicability to radiative capture reactions in astrophysics.
Radiative neutron capture rate of 19N(n, γ)20N
Authors: Singh G. , Shubhchintak  , Dan M. , Chatterjee R.
Published: December 2020

Low and medium mass neutron rich nuclei have been thought of as important constituents in the final abundance patterns resulting from the r-process reaction network calculations. However, a direct study of these nuclei is extremely difficult and indirect methods like Coulomb dissociation are used for their investigation. We calculate the reaction rate of the 19N(n,γ)20N radiative capture reaction using Coulomb dissociation of the medium mass exotic nucleus 20N, under the aegis of finite range distorted wave Born approximation theory and compare our results with those from the experiment. The reaction rate, when included in the full reaction network, is thought to be crucial to the final abundance of Fluorine isotopes.
Significance of lower energy density region of neutron star and universalities among neutron star properties
Authors: Husain Wasif , Thomas Anthony W.
Published: December 2020

We have constructed and compared models of rotating neutron stars and strange stars, within the Hartle framework. The significance of the low energy density region and crust region inside the neutron star has been studied, along with how much the existence of strange matter above the energy density 300 MeV/fm3 can affect the neutron star properties. We have confirmed several universalities among the neutron star properties such as, dimensionless moment of inertia vs dimensionless quadrupole moment, dimensionless tidal deformability vs dimensionless moment of inertia and moment of inertia parameters vs R/2M.
Experiments on astrophysical reactions with low-energy unstable nuclei beams at CRIB
Authors: Yamaguchi G. , Hayakawa S. , Ma N.R. , Shimizu H. , Yang L. , Kahl D. , Abe K. , Suhara T. , Iwasa N. , Kim A. , Kim D.H. , Cha S.M. , Kwag M.S. , Lee J.H. , Lee E.J. , Chae K.Y. , Wakabayashi Y. , Imai N. , Kitamura N. , Lee P. , Moon J.Y. , Lee K.B. , Akers C. , Jung H.S. , Duy N.N. , Khiem L.H. , Lee C.S. , Cherubini S. , Gulino M. , Spitaleri C. , Rapisarda G.G. , Cognata La , Lamia L. , Romano S. , Coc A. , de Sereville N. , Hammache F. , Kiss G. , Bishop S. , Teranishi T. , Kawabata T. , Kwon Y.K. , Binh D.N.
Published: December 2020

Studies on nuclear astrophysics, nuclear structure, and other interests have been performed using the radioactive-isotope (RI) beams at the low-energy RI beam separator CRIB, operated by Center for Nuclear Study (CNS), the University of Tokyo. The elastic resonant scattering is a striking tool to study astrophysical reactions and nuclear clusters. In particular, when it is coupled with a thick target and inverse kinematics, the measurement can be very efficient and even feasible with RI beams. By measuring resonant scattering, we can study the properties of resonant states which could play an important role in the astrophysical reaction, or have an exotic nuclear structure. The 10Be+α elastic scattering has been measured at CRIB, and three resonances which are in agreement with the prediction of a linear-chain structure by Suhara-En’yo were observed, giving a strong indication of the existence of such an exotic structure. Measurements based on the indirect technique of the reaction measurement, such as the Trojan horse method, have also been performed at CRIB.
Investigating the relation between heavy ion double charge exchange nuclear reactions and double beta decays
Authors: Bellone J I , Burrello S , Colonna M , Lay J A , Lenske H
Published: December 2020

Heavy ion double charge exchange reactions (DCE) are discussed, within DWBA, in synergy with the main goal of the NUMEN project, i. e. to extract information on the 0νββ decay nuclear matrix element from DCE cross section measurements. The first step to reach this goal is to assess the analogy between the DCE nuclear matrix element and that describing 0νββ decay; then it is necessary to single out a term related to the desired double beta decay nuclear matrix element from the DCE cross-section expression (cross section factorization).

Heavy ion DCE processes, are depicted in terms of sequence of two correlated or uncorrelated Single Charge Exchange (SCE) reactions, resembling in this way 0νββ and 2νββ decay, respectively. Here, the formalism for describing DCE reactions within the latter scenario is described.

Once provided the formalism leading both to SCE and DCE cross section factorization, together with its limitations, a preliminary comparison with experimental DCE data is shown.
Recent results on heavy-ion induced reactions of interest for neutrinoless double beta decay at INFN-LNS
Authors: Cappuzzello F. , Agodi C. , Acosta L. , Altana C. , Amador-Valenzuela P. , Auerbach N. , Barea J. , Bellone J. , Bijker R. , Bonanno D. , Borello-Lewin T. , Boztosun I. , Branchina V. , Brasolin S. , Brischetto G. , Brunasso O. , Burrello S. , Calabrese S. , Calabretta L. , Calvo D. , Capirossi V. , Carbone D. , Cavallaro M. , Garcia L.E. Charon , Chávez Lomelí E.R. , Chen R. , Ciraldo I. , Colonna M. , D’Agostino G. , Delaunay F. , Deshmukh N. , Djapo H. , Geronimo G. De , Los Rios K. De , Ferraresi C. , Ferreira J.L. , Ferretti J. , Finocchiaro P. , Firat S. , Fisichella M. , Foti A. , Gallo G. , Garcia-Tecocoatzi H. , Hacisalihoglu A. , Huerta-Hernandez A. , Kotila Z.J. , Kucuk Y. , Iazzi F. , Lanzalone G. , Lay J.A. , Fauci L. La , Via F. La , Lenske H. , Linares R. , Presti D. Lo , Lubian J. , Ma J. , Marín-Lámbarri D. , Ruiz J. Mas , Medina N.H. , Mendes D. R. , Mereu P. , Moralles M. , Neri L. , Oliveira J.R.B. , Pakou A. , Pandola L. , Petrascu H. , Pietralla N. , Pinna F. , Reito S. , Ries P. , Rodrigues M.R.D. , Russo A. D. , Russo G. , Santopinto E. , Santos R.B.B. , Serbina L. , Sgouros O. , da Silveira M.A.G. , Solakci S.O. , Souliotis G. , Soukeras V. , Spatafora A. , Torresi D. , Tudisco S. , Hernandez H. Vargas , Vsevolodovna R.I.M. , Wang J.S. , Werner V. , Yang Y.Y. , Yildirin A. , Zagatto V.A.B.
Published: December 2020

The NUMEN project aims at accessing experimentally driven information on Nuclear Matrix Elements (NME) involved in the half-life of the neutrinoless double beta decay (0νββ). In this view measurements of Heavy Ion (HI) induced Double Charge Exchange (DCE) reaction cross sections are performed with high-accuracy. In particular, the (18O,18Ne) and (20Ne,20O) reactions are used as tools for β+β+ and β-β- decays, respectively. In the experiments, performed at INFN - Laboratory Nazionali del Sud (LNS) in Catania, the beams are accelerated by the Superconducting Cyclotron (CS) and the reaction ejectiles are detected the MAGNEX magnetic spectrometer. The measured cross sections are challengingly low (a few nb), being the total reaction cross section much larger (a few b), thus a high sensitivity and a large rejection capability are demanded to the experimental set-up. This limits the present exploration to few selected isotopes of interest in the context of typically low-yield experimental runs. A major upgrade of the LNS facility is under way in order to increase the experimental dataset of more than two orders of magnitude, still preserving the high sensitivity of the present set-up. When accomplished this effort will make the INFN-LNS as the state-of-the-art research infrastructure for the systematic study of all the cases of interest for 0νββ. In this view, frontiers technologies are going to be adopted for the accelerator and the detection systems. In parallel, advanced theoretical models are being developed in order to extract the nuclear structure information from the measured cross sections.
New features of the INCL model for spallation reactions
Authors: David J.-C. , Boudard A. , Cugnon J. , Hirtz J. , Leray S. , Mancusi D. , Rodriguez-Sanchez J. L.
Published: December 2020

The recent developments of the Liège intranuclear cascade model INCL are reviewed. The INCL4.6 version of this model was able when coupled with the ABLA07 de-excitation code, to describe rather well a huge set of experimental data in an incident energy range spanning between 200 MeV and 3 GeV, as it has been testified by an intercomparison of spallation codes organized by the IAEA. Since that time, the model has been implemented in several nuclear particle transport codes. Therefore, the possible applications of INCL have been enlarged to focus on diverse fields, and in the recent years, the model has been further developed to be applicable to these new issues and also to cope with remaining deficiencies. The new features include: i) a sophisticated dynamical model for light cluster emission (up to O ions), ii) the accommodation of light nuclei as projectiles, iii) a new procedure to take account of the fuzziness of the Fermi surface, and iv) an extension of the model to higher energy. The aim of this contribution is to present for the first time and to discuss the physics of the added features, and to give a hint about the performances of the new model.
Nuclear “diffuseness” probed by proton-nucleus diffraction
Authors: Horiuchi W. , Hatakeyama S. , Kohama A.
Published: December 2020

In this contribution, we propose a way to probe nuclear density profile, especially, nuclear surface diffuseness. We discuss the relationship between the nuclear surface diffuseness and the elastic scattering differential cross section at the first diffraction peak of high-energy nucleon-nucleus scattering as an efficient tool for extracting the nuclear surface information from limited experimental data involving short-lived unstable nuclei. The high-energy reaction is described by a reliable reaction theory, the Glauber model. Extending the idea of the black sphere diffraction model, we find that the nuclear radius and surface diffuseness are reflected in the proton-nucleus elastic scattering diffraction at the first peak position, that is, one can extract both the nuclear radius and diffuseness simultaneously, using the position of the first diffraction peak and its magnitude of the elastic scattering differential cross section. The reliability of this approach is confirmed by using realistic density distributions obtained by a microscopic mean-field model. The possibility of separating neutron and proton surfaces is also discussed.
Studying the Pygmy Dipole Resonances with isoscalar and isovector probes
Authors: Lanza E G , Vitturi A , Andrès M V
Published: December 2020

We present a short review of the properties of the so-called Pygmy Dipole Resonance (PDR) which can be studied with both isovector and isoscalar probes. This is possible due to the particular property of this new mode where the isoscalar and isovector characters are mixed. The use of both probes unveils new features which otherwise will remain hidden. It is of paramount importance the use of a proper description of these modes, taking into account their main features, in order to have a good description of the experimental data.
Scaling with deformation in probable p-wave halo 34Na
Authors: Manju  , Singh Jagjit , Shubhchintak  , Chatterjee R.
Published: December 2020

We investigate the electric dipole response of 34Na, a probable p-wave one-neutron halo nucleus, lying in the “island of inversion” and having a deformed structure. We use a semi-analytic approach to probe the dipole response and further compare the results obtained from a post form finite-range distorted wave Born approximation theory of Coulomb breakup. The effects of deformation are figured out on the peak positions of the electric dipole strength distribution which further constraint the one-neutron separation energy of the deformed projectile and it leads to a two-dimensional scaling of total B(E1) strength with parameters: separation energy and deformation.
Isospin equilibration phenomenon and mid-rapidity IMF emission in the
48Ca +27
Al 40 MeV/nucleon collision
Authors: Papa M , Acosta L , Cardella G , Filippo E De , Favela F , Geraci E , Gnoffo B , Lanzalone G , Maiolino C , Martorana N S , Pagano A , Pagano E V , Pirrone S , Politi G , Quattrocchi L , Rizzo F , Russotto P , Trifiro’ A , Trimarchi M
Published: December 2020

It is discussed the dynamics of Isospin equilibration in reactions involving the production of Intermediate Mass Fragment (IMF) in the mid-rapidity region. The investigation proceeds through the measurements of the reduced value of the total dipolar signal obtained from the measured velocities and charges of all fragments produced in the collision 48
Ca +27
Al at 40 MeV/nucleon. Preliminary experimental results, along with the comparison with CoMD-III model calculations for different density functionals related to the symmetry energy, are presented.