bluuebunny/crossref_metadata_2025 huggingface dataset:
Mecanismos de transmissão das políticas monetárias: uma investigação sobre ação e efeitos
Authors: Strachman Eduardo
Published: November 2022

O artigo busca compreender os mecanismos de transmissão da política monetária e se resultam nos efeitos desejados. Definimos e detalhamos os mecanismos de transmissão da política monetária. Mostramos mudanças recentes no conhecimento sobre economia monetária. Salientamos que Bancos Centrais (BC) modernos determinam juros como mecanismo fundamental de política monetária, em vez de metas para agregados monetários. Esclarecemos os canais através dos quais a política monetária se transmite e expomos a efetividade diferenciada dos mecanismos de transmissão da política monetária, conforme a fase do ciclo, investigando os impactos e a endogeneidade aos ciclos dos riscos, não conduzindo a qualquer ótimo.
Oficinas do ReNP
Authors: Carneiro Luiz Phelipe da Silva Maia , Breder Matheus Benini , Ribeiro Raphael Geraldo Estanislau Vaz , Santos Thiago César Carvalho dos
Published: November 2022

Trata-se de um estudo de caso das oficinas realizadas pela AJUP-UFMG, conjuntamente ao Grupo de Amigos e Familiares de Pessoas Privadas de Liberdade, sobre o Regulamento de Normas e Procedimentos do Sistema Prisional de Minas Gerais, durante o período de pandemia. Utilizou-se o método freiriano de educação popular, considerando que este não finda no aspecto metodológico, mas toma forma também enquanto prática política. As oficinas atingiram sobretudo familiares que agem enquanto lideranças e referências regionais, majoritariamente mulheres negras periféricas, gerando ações em diversas esferas. Conclui-se que a experiência das oficinas, sem pretensão de universalidade, contribui ao debate sobre educação popular em direitos humanos e no combate ao encarceramento em massa e ao populismo penal.
Religiosidade afro-brasileira, educação para as relações étnico-raciais e a formação docente na perspectiva da sociointeratividade
Authors: Portuguez Anderson Pereira , Marcelino Mical de Melo
Published: November 2022

O presente artigo relata a experiência extensionista “Estágios de vivência: cultura afro-brasileira e educação para as relações étnico-raciais”. Trata-se de uma iniciativa de inspiração sociointeracionista, que visou subsidiar processos de formação docente (inicial e continuada) antirracista, por meio de estágios de vivência em comunidades de tradição afro-brasileira. Para tanto, promovemos um dia de vivência, de forma que os professores puderam conhecer um terreiro de Candomblé, no qual realizaram atividades de leitura, assim como conheceram a dinâmica de funcionamento de uma comunidade de axé. Observamos que o contato com a comunidade receptora possibilitou a revisão de preconceitos e de estereótipos. Além disso, permitiu ao grupo aprofundar reflexões, visando a educação antirracista e a participação da escola no combate à intolerância religiosa e implementação das Leis Federais nº 10.639/2003 e nº 11.645/2008.
Experiência de formação remota de lideranças comunitárias no SUS durante a pandemia de Covid-19
Authors: Tavares Yasmin Maria Sátiro Cruz , Anacleto Ruth Maria Mendonça , Gomes Daiana de Paiva , Barbosa Daniella de Souza
Published: November 2022

Este trabalho tem como objetivo fomentar espaços formativos de lideranças comunitárias, sob a dimensão político-pedagógica da Educação Popular em Saúde (EPS), para o exercício pleno e equitativo dos princípios de participação popular e do controle social nos espaços que compõem a Atenção Primária à Saúde do Sistema Único de Saúde (SUS) de João Pessoa-PB. A experiência do curso se deu por meio da realização de 11 encontros virtuais realizados via plataforma Google Meet, de modo semanal, durante três meses consecutivos, das quais participaram 11 facilitadores externos que trabalham a EPS de forma teórico-prática, 4 docentes e 4 extensionistas e 51 cursistas. Como resultado, percebeu-se que o projeto auxiliou na formação de possíveis lideranças comunitárias e na ideação de um futuro a partir de um ensino-aprendizagem problematizador, direcionado para a realidade na qual esses atores estão inseridos, despertando em todos os envolvidos um sentimento de “esperançar”. Conclui-se que o curso, por meio da troca de saberes e de práticas populares, comprovou a eficácia da EPS como potente instrumento de fortalecimento e efetivação da participação popular em saúde no SUS, favorecendo a formação de lideranças comunitárias, mesmo a partir do ensino remoto.
Na trama das experiências educativas e formativas emancipatórias
Authors: Souza Tiago Zanquêta de , Novais Gercina Santana
Published: November 2022

Este texto apresenta narrativas refletidas sobre a criação e implementação da Rede Cooperativa de Ensino, Pesquisa e Extensão em Escolas de Educação Básica (RECEPE), em tempos de pandemia de Covid-19. Ele revela sinais das tramas de experiências educativas, formativas e coletivas dos encontros com profissionais da Rede de Educação Básica e de outros espaços formativos no movimento permanente de construção e desenvolvimento da referida Rede, no âmbito do município de Uberlândia-MG. Assim, em termos estruturais, o texto está organizado em três seções: a primeira retoma as narrativas de profissionais da educação básica cooperados da RECEPE, bem como o contexto de produção dessas narrativas, acompanhado das evidências da potencialidade da escuta interessada. A segunda traz as experiências anteriores à criação da RECEPE, e a terceira apresenta narrativas refletivas sobre ela. Por último, é preciso considerar que o trabalho no âmbito da RECEPE é colaborativo-solidário, que prima pela perspectiva de pesquisa militante, de extensão popular e ensino problematizador, pautando a elaboração e implementação de projetos interventivos de ensino, pesquisa e extensão que estejam em diálogo com os pressupostos da Educação Popular, em defesa de uma educação transformadora.
Potencialidades e desafios das práticas educativas em Promoção da Saúde e Segurança Alimentar Nutricional na Atenção Básica
Authors: Silva Edileuza Ricardo da , Vieira Gabriel Nóbrega , Cruz Pedro José Santos Carneiro , Oliveira João Batista de
Published: November 2022

O presente artigo apresenta resultados de pesquisa cujo objeto central rescindiu na análise de uma experiência com práticas educativas em grupos comunitários na Atenção Básica (AB), pautada pela perspectiva pedagógica freiriana da educação popular (EP). Seu processo investigativo teve, como fio condutor, o desvelamento de desafios nesse contexto, tendo também, como objeto, a experiência do Programa de Extensão “PINAB – Práticas Integrais de Promoção da Saúde e Nutrição na Atenção Básica”, vinculado ao Departamento de Nutrição/CCS e ao Departamento de Promoção da Saúde/CCM da Universidade Federal da Paraíba. O caminho investigativo foi construído por meio de uma pesquisa qualitativa feita com a realização de entrevistas, com abordagem oral e individual. Foram valorizadas percepções de diferentes sujeitos das comunidades em que atua o referido programa de extensão, como de trabalhadores da Unidade de Saúde da Família Vila Saúde, todos efetivos participantes das práticas educativas analisadas criticamente nesta pesquisa. Como potencialidade, viu-se que o PINAB atua na AB com Grupos Operativos, frentes essas que servem de alicerce para o Programa, buscando a construção de uma visão humanizada da saúde com o olhar voltado para a integralidade do indivíduo, bem como associada à realidade social das comunidades, trabalhando de forma interdisciplinar e buscando compreender a complexidade do sujeito em uma atividade integral.
Pustá země T. S. Eliota ve dvou českých překladech
Authors: Eliáš Petr
Published: November 2022

The article analyses two Czech translations of T. S. Eliot’s The Waste Land, both by members of the Group 42. Jiřina Hauková and Jindřich Chalupecký were the first to translate a complete text, including author’s notes. Jiří Kolář and Jiří Kotalík translated the fifth part of the poem. After a brief introduction describing the genesis of the original text and listing the existing Czech translations, the article analyses both translations separately, as well as in comparison, considering all the relevant criteria. Through a detailed analysis of the poetic devices used by Eliot and his translators, the article delivers a complex description of the methods used by respective translators showing that Hauková and Chalupecký emphasize meaning to the detriment of sound, the translation lacking rhythm and rhymes. The version by Kolář and Kotalík is much more condensed, rhythmical, and more accomplished.
Překlady české literatury v Mexiku: příběhy geneze překladu z pohledu překladatelů
Authors: Strnadová Karolína
Published: November 2022

This paper presents the particularities of translations of Czech literature into Spanish published in Mexico and focuses on the role of the translator in the translation-publishing process and on the genesis of a translation. The first aim is to discuss the particularities of literary translation from Czech into Spanish in relation to the book market in Spanish-speaking countries and to draw attention to the role of Spain and the different contexts of translation production outside this country. The second objective of this paper is to give voice to the five interviewed translators and, with the help of the obtained material and their statements, to interpret the relevant particularities of translation-publishing process on the axis author – original – translator – publisher – translation – reader. The main part of the paper consists of individual testimonies of contemporary translators whose Spanish translations of one or more Czech literary titles were published in Mexico. The testimonies, obtained by the method of interview, brought a new insight into the topic of Mexican translations of Czech literature and valuable information on the circumstances of a particular translation work’s genesis. The source of the presented results and the quoted translators’ statements is the research by Strnadová (2021) presented in the rigorosum thesis Translations of Czech Literature in Mexico, taking into account the Czech translations of Mexican literature.
Estudio de la variación fraseológica diatópica del español de España y de Argentina basado en corpus de sentencias: propuestas de traducción al alemán
Authors: Cuadrado Rey Analía
Published: November 2022

This article is related to the study of specialized translation, specifically to lexical and phraseological variation in legal translation. In fact, this study arises from the need to delve deeper into the study of Spanish phraseological units using larger corpora, considering the varieties that reflect the convergences and divergences of this language throughout the places where it is spoken. To this end, the paper approaches sentences using a comparative corpus-based approach analysing phraseological units used in Argentine and Spain. The research provides a brief contextualization of the legal systems of the selected countries, and, by using corpus linguistics, the PUs are extracted and compared. The main objective is to detect similarities and differences at the phraseological level in both languages and to provide functional equivalents in German that can be useful for students and translators. The findings show that at the methodological level corpus linguistics is a useful tool for the identification of PUs in specialized texts. Furthermore, the analysis of the examples from the corpus of sentences shows the evidence of lexical variants referring to the same reality both within a single variety of Spanish and between different varieties. This consequently determines the need to further study the PUs of Spanish by using a more extensive corpus, considering the different countries in which Spanish is an official language.
Bohuslav Mánek pětasedmdesátiletý
Authors: Vraštilová Olga
Published: November 2022

Laudatio
Tomáš Svoboda (ed.) (2019) Překlady pro EU. Institucionální překlad v kontextu institucí a orgánů Evropské unie
Authors: Petrů Ivo
Published: November 2022

Book review on Tomáš Svoboda (ed.) (2019) Překlady pro EU. Institucionální překlad v kontextu institucí a orgánů Evropské unie, Praha: Nakladatelství Milada Karez.
Koncepcja artystyczna ukraińskiego panteonu kultury w dramaturgii Wałerija Herasymczuka
Authors: Kaspicz Hałyna , Polarusz Nina
Published: November 2022

Artykuł jest poświęcony zbadaniu motywów cyklu Dramaty o Wielkich jako całości dość złożonej i wielopoziomowej, gdyż Wałerij Herasymczuk pracuje w różnych strategiach dramatu biograficznego. Wybrany kierunek badań wydaje się właściwy z punktu widzenia różnych modeli współczesnej biografii dramaturgicznej, komponentów jej formy i treści. Uwaga badaczek skupia się na procesie nowego przeformatowania ukraińskiego kanonu kulturowo-historycznego. Wałerij Herasymczuk portretuje postaci metropolity Andrzeja Szeptyckiego, pisarza i scenarzysty Oleksandra Dowżenki, historyka Dmytra Jawornickiego, pisarza Antona Czechowa czy sympatyzującego z Ukrainą malarza Ilji Riepina. Na przykładzie dwu ostatnich dramaturg wyrażą ważną ideę – powrotuetnicznych Ukraińców zawłaszczonych przez kulturę imperialną do ukraińskiego panteonu. W ten sposób przypomina ukraińskiemu czytelnikowi/widzowi, że kanon narodowy nie ogranicza się do znanych nazwisk, zachęca do lektury, aby dowiedzieć się więcej o przeszłości i bohaterach narodowych.
Obrazy wizualne: od powieści Iwana Bahrianego Łowcy tygrysów do ekranizacji Rostysława Syńki
Authors: Makaradze Chrystyna
Published: November 2022

Ekranizacja powieści wpisuje się w dyskurs literacki, jej analiza jest jednym ze sposobów ujawnienia osadzonych w dziele intencji autora. W artykule podjęto próbę zbadania, jakie obrazy wizualne łączą powieść Iwana Bahrianego Łowcy tygrysów i film Rostysława Syńki o tym samym tytule. Celem artykułu jest porównanie wizualnych obrazów obu dzieł z uwzględnieniem specyfiki literatury i kina jako rodzajów sztuki oraz określenie przyczyn i roli zmian wprowadzonych przez reżysera. Spośród obrazów wizualnych zwróciłam uwagę na wizerunek pociągu, cechy portretowe postaci, wnętrze i zewnętrze domu Sirków oraz krajobrazy. W wyniku analizy wyciągnęłam następujące wnioski: ekranizacja powieści Łowcy tygrysów niemal dokładnie odtwarza werbalne obrazy wizualne, ale wzmacnia ich ideologię poprzez podkreślenie cech ukraińskich. Reżyser stara się obejść techniczną niemożność oddania malowniczych pejzaży Dalekiego Wschodu i posługuje się stylizacją, wysuwając na pierwszy plan motyw patriotyczny i wątek przygodowy.
Mało znana baśniowa proza Jewhena Hrebinki: problematyka i poetyka
Authors: Terechowa Iryna
Published: November 2022

W artykule omówiono podstawowe zasady rozwoju baśni literackiej w dobie romantyzmu ukraińskiego. Za pomocą metod genetycznych, porównawczych, typologicznych oraz analizy i syntezy udowodniono, że baśniowa proza Jewhena Hrebinki jest oryginalnym i nowatorskim zjawiskiem w literaturze ukraińskiej XIX wieku, którego specyfika artystyczna polega na syntezie cech opowieści magicznej i liryzmu, zasad moralno-dydaktycznych i folkloru. W opracowaniu przeanalizowano cechy problematyki i poetyki takich opowiadań autora, jak Straszna bestia, Księżyc i słońce, Macocha i panna. Ustalono, że baśniowe dzieła Jewhena Hrebinki stanowią całość artystyczną, zbudowaną na wspólnym modelu fabularnym i realizacji takiego rodzaju konfliktu artystycznego, który przejawia się w zderzeniu postaci pozytywnych i negatywnych.
The case for distributed shared-memory databases with RDMA-enabled memory disaggregation
Authors: Wang Ruihong , Wang Jianguo , Idreos Stratos , Özsu M. Tamer , Aref Walid G.
Published: November 2022

Memory disaggregation (MD) allows for scalable and elastic data center design by separating compute (CPU) from memory. With MD, compute and memory are no longer coupled into the same server box. Instead, they are connected to each other via ultra-fast networking such as RDMA. MD can bring many advantages, e.g., higher memory utilization, better independent scaling (of compute and memory), and lower cost of ownership. This paper makes the case that MD can fuel the next wave of innovation on database systems. We observe that MD revives the great debate of "shared what" in the database community. We envision that
distributed shared-memory databases (DSM-DB, for short)
- that have not received much attention before - can be promising in the future with MD. We present a list of challenges and opportunities that can inspire next steps in system design making the case for DSM-DB.
FlexChain
Authors: Wu Chenyuan , Amiri Mohammad Javad , Asch Jared , Nagda Heena , Zhang Qizhen , Loo Boon Thau
Published: November 2022

While permissioned blockchains enable a family of data center applications, existing systems suffer from imbalanced loads across compute and memory, exacerbating the underutilization of cloud resources. This paper presents
FlexChain
, a novel permissioned blockchain system that addresses this challenge by physically disaggregating CPUs, DRAM, and storage devices to process different blockchain workloads efficiently. Disaggregation allows blockchain service providers to upgrade and expand hardware resources independently to support a wide range of smart contracts with diverse CPU and memory demands. Moreover, it ensures efficient resource utilization and hence prevents resource fragmentation in a data center. We have explored the design of XOV blockchain systems in a disaggregated fashion and developed a tiered key-value store that can elastically scale its memory and storage. Our design significantly speeds up the execution stage. We have also leveraged several techniques to parallelize the validation stage in FlexChain to further improve the overall blockchain performance. Our evaluation results show that FlexChain can provide independent compute and memory scalability, while incurring at most 12.8% disaggregation overhead. FlexChain achieves almost identical throughput as the state-of-the-art distributed approaches with significantly lower memory and CPU consumption for compute-intensive and memory-intensive workloads respectively.
MiCS
Authors: Zhang Zhen , Zheng Shuai , Wang Yida , Chiu Justin , Karypis George , Chilimbi Trishul , Li Mu , Jin Xin
Published: November 2022

Existing general purpose frameworks for gigantic model training, i.e., dense models with billions of parameters, cannot scale efficiently on cloud environment with various networking conditions due to large communication overheads. In this paper, we propose MiCS, which Minimizes the Communication Scale to bring down communication overhead. Specifically, by decreasing the number of participants in a communication collective, MiCS can utilize heterogeneous network bandwidth, reduce network traffic over slower links, reduce the latency of communications for maintaining high network bandwidth utilization, and amortize expensive global gradient synchronization overhead. Our evaluation on AWS shows that the system throughput of MiCS is up to 2.89× that of the state-of-the-art large model training systems. MiCS achieves near-linear scaling efficiency, which is up to 1.27× that of DeepSpeed. MiCS allows us to train a proprietary model with 100 billion parameters on 512 GPUs with 99.4% weak-scaling efficiency, and it is able to saturate over 54.5% theoretical computation power of each GPU on a public cloud with less GPU memory and more restricted networks than DGX-A100 clusters.
SIFTER
Authors: Skitsas Konstantinos , Papageorgiou Ioannis G. , Talebi Mohammad Sadegh , Kantere Verena , Katehakis Michael N. , Karras Panagiotis
Published: November 2022

Can we solve finite-horizon Markov decision processes (FHMDPs) while raising low memory requirements? Such models find application in many cases where a decision-making agent needs to act in a probabilistic environment, from resource management to medicine to service provisioning. However, computing optimal policies such an agent should follow by dynamic programming value iteration raises either prohibitive space complexity, or, in reverse, non-scalable time complexity requirements. This scalability question has been largely neglected. In this paper, we propose SIFTER (Space Efficient Finite Horizon MDPs), a suite of algorithms that achieve a golden middle between space and time requirements. Our former algorithm raises space complexity growing with the square root of the horizon's length without a time-complexity overhead, while the latter's space requirements depend only logarithmically in horizon length with a corresponding logarithmic time complexity overhead. A thorough experimental study under diverse settings confirms that SIFTER algorithms achieve the predicted gains, while approximation techniques do not achieve the same combination of time efficiency, space efficiency, and result quality.
Mensurando a transparência governamental das contratações emergenciais para o combate da Covid-19 em Sergipe: contribuição para o controle da Gestão Pública
Authors: Andrade de Cerqueira Teles Janaina , Maisa Ribeiro de Santana Deise , Melo de Carvalho Kleverton , Sarmento Silva Rosângela
Published: November 2022

Este artigo tem como objetivo mensurar a transparência governamental em municípios do estado de Sergipe nas contratações emergenciais para o combate da Covid-19, a partir do desenvolvimento de um índice específico. De caráter descritivo e qualitativo, este estudo de caso examinou 75 municípios sergipanos com base nos indicadores de transparência pública estabelecidos pela organização Transparência Internacional Brasil, na legislação brasileira e literatura especializada. Construiu-se um modelo de análise, fundamentando o desenvolvimento de um “índice de transparência de informação no combate à Covid-19” (ITI-COVID). Tal índice foi aplicado nos municípios investigados, o que permitiu perceber que há transparência no seu sentido intrínseco de divulgação de informação, mas não instrumental, ou seja, como ferramenta para promover accountability. A partir do índice utilizado, identificou-se que mais de 80% dos municípios sergipanos apresentam níveis insuficientes de transparência pública, o que os qualificam dentro do conceito de “transparência opaca” de Fox.
Composição florística e diagnose ambiental de um fragmento florestal de Cerrado na bacia hidrográfica do Rio Uberaba
Authors: Gomes Júnior Juarez Antônio , Braga Júnior Aguinaldo José , Milla dos Santos Senhuk Ana Paula
Published: November 2022

A fragmentação promove a redução do hábitat original, o aumento do número das manchas de vegetação e o distanciamento entre elas, assim compromete as funções ecossistêmicas. O presente estudo caracterizou um fragmento florestal de Cerrado, situado na bacia hidrográfica do Rio Uberaba,     Uberaba-MG, quanto às áreas de restrição ambiental, aos impactos ambientais negativos e à flora arbustiva e arbórea. Coletas de exemplares botânicos férteis foram realizadas quinzenalmente por 12 meses em 5 transectos aleatórios. Amostras de ramos com flores e/ou frutos coletadas foram prensadas e secas em estufa para armazenamento na coleção botânica do Herbário de Uberaba (URA). A identificação dos táxons foi feita por meio de chaves de identificação, revisões taxonômicas e consulta a especialistas. Para calcular a similaridade florística com outras áreas na região, foi utilizado o índice de Sörensen. Pelo mapeamento da cobertura e uso alternativo do solo verificou-se a predominância de mata seca (40,39%), cerradão (37,64%) e a presença de paisagens relacionadas às atividades antrópicas, como pastagem com reflorestamento (6,34%) e plantação de eucaliptos (2,04%). Quanto aos impactos ambientais negativos, destacou-se as atividades de motocross que tem compactado o solo e acelerado os processos erosivos. Foram amostradas 82 espécies, distribuídas em 36 famílias, com destaque para Fabaceae (52,7% da diversidade). O fragmento florestal estudado apresentou 14% e 37% de similaridade com outras duas áreas, destacando espécies em comum protegidas por lei como Caryocar brasiliense e Handroanthus chrysotrichus. Os resultados são de grande importância para subsidiar práticas sustentáveis e a tomada de decisões por gestores ambientais locais.
Desenvolvimento e validação de uma atividade POGIL para ser aplicada em aulas práticas de química
Authors: Freire de Santana Jhonatas , Almeida Simões Rodrigo , Viana Simões Ana Carolina , Nogueira Saraiva Natália
Published: November 2022

As aulas práticas de Química, geralmente, são ministradas através do método de ensino tradicional. No entanto, tem-se observado que essa abordagem vem se tornando cada vez menos eficaz no entendimento dos discentes sobre os assuntos abordados, havendo a necessidade de buscar metodologias alternativas. Nesse sentido, o presente trabalho teve como objetivo desenvolver e validar por meio da técnica Delphi uma atividade POGIL para ser aplicado em aulas práticas de química como uma alternativa à abordagem tradicional. Para isso, foi realizada a construção de um roteiro prático semiestruturado no formato POGIL abordando o assunto de Cromatografia em Camada Delgada Analítica (CCDA). Em seguida, o instrumento foi submetido a validação pelo método Delphi, sendo avaliado por um painel de especialistas composto por cinco juízes. Após duas rodadas de avaliação, todos os itens do instrumento foram validados, apresentando Índice de Validade de Conteúdo (IVC) de 100%. A partir do trabalho, foi possível obter um instrumento validado que poderá ser utilizado em aulas práticas que abordem o assunto de CCDA e que também se deseje avaliar a eficácia da metodologia POGIL como uma alternativa à abordagem tradicional.
Mucin 13 (MUC13) as a candidate biomarker for ovarian cancer detection: potential to complement CA125 in detecting non-serous subtypes
Authors: Ren Annie H. , Filippou Panagiota S. , Soosaipillai Antoninus , Dimitrakopoulos Lampros , Korbakis Dimitrios , Leung Felix , Kulasingam Vathany , Bernardini Marcus Q. , Diamandis Eleftherios P.
Published: November 2022

Objectives

Ovarian cancer is the most lethal gynecological malignancy in developed countries. One of the key associations with the high mortality rate is diagnosis at late stages. This clinical limitation is primarily due to a lack of distinct symptoms and detection at the early stages. The ovarian cancer biomarker, CA125, is mainly effective for identifying serous ovarian carcinomas, leaving a gap in non-serous ovarian cancer detection. Mucin 13 (MUC13) is a transmembrane, glycosylated protein with aberrant expression in malignancies, including ovarian cancer. We explored the potential of MUC13 to complement CA125 as an ovarian cancer biomarker, by evaluating its ability to discriminate serous and non-serous subtypes of ovarian cancer at FIGO stages I–IV from benign conditions.

Methods

We used our newly developed, high sensitivity ELISA to measure MUC13 protein in a large, well-defined cohort of 389 serum samples from patients with ovarian cancer and benign conditions.

Results

MUC13 and CA125 serum levels were elevated in malignant compared to benign cases (p<0.0001). Receiver-operating characteristic (ROC) curve analysis showed similar area under the curve (AUC) of 0.74 (MUC13) and 0.76 (CA125). MUC13 concentrations were significantly higher in mucinous adenocarcinomas compared to benign controls (p=0.0005), with AUC of 0.80. MUC13 and CA125 showed significant elevation in early-stage cases (stage I–II) in relation to benign controls (p=0.0012 and p=0.014, respectively).

Conclusions

We report the novel role of MUC13 as a serum ovarian cancer biomarker, where it could complement CA125 for detecting some subtypes of non-serous ovarian carcinoma and early-stage disease.
Developing a machine learning prediction algorithm for early differentiation of urosepsis from urinary tract infection
Authors: Su Mingkuan , Guo Jianfeng , Chen Hongbin , Huang Jiancheng
Published: November 2022

Objectives

Early recognition and timely intervention for urosepsis are key to reducing morbidity and mortality. Blood culture has low sensitivity, and a long turnaround time makes meeting the needs of clinical diagnosis difficult. This study aimed to use biomarkers to build a machine learning model for early prediction of urosepsis.

Methods

Through retrospective analysis, we screened 157 patients with urosepsis and 417 patients with urinary tract infection. Laboratory data of the study participants were collected, including data on biomarkers, such as procalcitonin, D-dimer, and C-reactive protein. We split the data into training (80%) and validation datasets (20%) and determined the average model prediction accuracy through cross-validation.

Results

In total, 26 variables were initially screened and 18 were statistically significant. The influence of the 18 variables was sorted using three ranking methods to further determine the best combination of variables. The Gini importance ranking method was found to be suitable for variable filtering. The accuracy rates of the six machine learning models in predicting urosepsis were all higher than 80%, and the performance of the artificial neural network (ANN) was the best among all. When the ANN included the eight biomarkers with the highest influence ranking, its model had the best prediction performance, with an accuracy rate of 92.9% and an area under the receiver operating characteristic curve of 0.946.

Conclusions

Urosepsis can be predicted using only the top eight biomarkers determined by the ranking method. This data-driven predictive model will enable clinicians to make quick and accurate diagnoses.
The harmonization issue in laboratory medicine: the commitment of CCLM
Authors: Zaninotto Martina , Graziani Maria Stella , Plebani Mario
Published: November 2022

The analytical quality of the clinical laboratory results has shown a significant improvement over the past decades, thanks to the joint efforts of different stakeholders, while the comparability among the results produced by different laboratories and methods still presents some critical issues. During these years, Clinical Chemistry and Laboratory Medicine (CCLM) published several papers on the harmonization issue over all steps in the Total Testing Process, training an important number of laboratory professionals in evaluating and monitoring all the criticisms inherent to the pre-analytical, as well as analytical and post analytical phases: from the consensus statement on the most informative testing in emergency setting, to the prevention and detection of hemolysis or to patients identification and tube labeling procedures, as far as to different approaches to harmonize hormones measurements or to describe new reference methods or to harmonize the laboratory report. During these years the commitment of the journal, devoted to the harmonization processes has allowed to improve the awareness on the topic and to provide specific instruments to monitor the rate of errors and to improve patients safety.
Coagulation activity of liquid extraction of Leucaena leucocephala and Sesbania grandiflora on the removal of turbidity
Authors: Putra Rudy Syah , Nasriyanti Desi , Sarkawi Muhammad
Published: November 2022

Turbidity is removed by adding a chemical coagulant, which produces a secondary toxic of alumina residues in the water. Therefore, the aim of study was to evaluate the coagulation activity of NaCl extract from Leucaena leucocephala and Sesbania grandiflora seeds on the removal of turbidity for water purification. The proximate composition of the seeds was determined. Fourier transform infrared spectroscopy was used to identify the functional groups of protein, and the surface morphology was observed by SEM-EDS. To obtain the optimized condition, all experiments were evaluated by artificial turbid water before being applied on the natural water (i.e., Selokan Mataram). The coagulation process was evaluated by concentration (M), dosage (mL/L), and pH in terms of turbidity, total dissolved solids, and transmittance of light. The results showed that both coagulant seeds contained 25.32 and 30.81% of protein. These coagulants could remove the turbidity by 99.7% for L. leucocephala and 94.24% for S. grandiflora from artificial turbid water at the optimized concentration of 1.0 M, and dosage of 5 and 10 mL/L, respectively. At pH 5 the removal of turbidity from Selokan Mataram was 99.4% for L. leucocephala and 97.23% for S. grandiflora.
Numerical simulation and mathematical modeling of the casting process for pearlitic spheroidal graphite cast iron
Authors: Şensoy Abdullah Tahir
Published: November 2022

Fluidity, an essential parameter in casting operations, is influenced by the thermal properties of the alloy and the mold, pouring temperature, modification, and inoculation of the alloy. In this work, pearlitic spheroidal graphite cast iron (PSGI) was studied in terms of fluidity characteristics. The sand mold used had different section thicknesses. The alloy was cast at pouring temperatures changing between 1,360–1,480°C. Liquid metal quality ranged between 10 and 90% where the section thickness was changed from 1 to 5 mm. FlowCast simulation tool was used for the modeling of the tests. The analysis of variance results of the response surface model constructed between certain casting parameters and fluidity length have shown that the reduced regression equation is very accurate in terms of statistical indicators (predicted R
2: 0.99). The sensitivity analysis has shown that the section thickness is the most dominant parameter on the fluidity, while metallurgical quality is the least. The proposed model was also compared with the studies in the literature and it was seen that the results are well-matched. Therefore, it was suggested to use the proposed equation in order to estimate the fluidity results of PSGI without the need for real casting operations.
Lucretius’prolepsis
Authors: Rover Chiara
Published: November 2022

This paper aims to investigate the equivalent of Epicurus’ πρόληψις, the second criterion of the Epicurean Canonic (DL X 31 = fr. 35 Usener), in Lucretius’De rerum natura(DRN). Taking stock of the several occurrences of the Latin termsnotitiaandnotitiesin the six books of the poem, I show that Lucretius’ view about preconception remains faithful to Epicurus’ πρόληψις, and that the poet does not endorse a less empiricist position than his Master because of some influence of the Stoic ἔννοια. To this end, I will also briefly address an important case in which πρόληψις, albeit not clearly mentioned, plays an essential role, namely theprolepsisof the deity (DRNV 1169–1182). Finally, I explain how Lucretius can be of some help in grasping the controversial relationship between the criterion of πρόληψις and that of ἐπιβολὴ τῆς διανοίας (animi inectus/iactus), showing in which way the poet seems to consider the latter as a criterion of truth in its own right.
Reminiscenze di Aristotele,MetafisicaIX 6.1048b18–35 in autori neoplatonici
Authors: Linguiti Alessandro
Published: November 2022

In Proclus’Platonic Theology(V 17, 62. 22–63. 2) one can detect a clear recollection of the well-known and much discussed passage 1048b18–35 fromMetaphysicsIX 6. This passage is transmitted in only one branch of the manuscript tradition and some scholars maintain that it is not by Aristotle or that it does not belong to hisMetaphysics. On the other hand, Proclus’ testimony, supported by other passages by Neo-Platonic authors, provides an argument for the original location of the discussed section in Aristotle’sMetaphysics.
The Antecedents to Habitual Entrepreneurship: Exploring the Role of Entrepreneurs’ Narcissism and Educational Level
Authors: Leonelli Simona
Published: November 2022

This paper aims to analyze the antecedents leading to habitual entrepreneurship by investigating the role of entrepreneurs’ narcissism and their level of education. While the literature provides a general understanding of what motivates individuals to pursue their entrepreneurial ideas, the possible antecedents to the individual’s decision to become a habitual entrepreneur remain unexplored and untested. Relying on a sample of 343 start-up entrepreneurs, hypotheses are tested through the partial least squares analysis. Results show that entrepreneurs’ educational levels fully mediate the relationship between narcissism and the choice to become habitual entrepreneurs. The study contributes to the literature on entrepreneurs’ personality, decision-making, and human capital, also underlining a few practical implications.
Wo steht die Friedensbewegung und was steht an?
Authors: Leistner Alexander
Published: November 2022

Der erneute russische Angriff auf die Ukraine hat zeitweilig auch das öffentliche Interesse auf die Friedensbewegung gelenkt und fragen lassen, ob es diese noch gibt und ob ihr über den Weg zu trauen ist. Das Interesse verrät zugleich etwas über die Bedeutung dieser für die bundesrepublikanische Geschichte so wichtigen Protestbewegung. Der Beitrag versucht eine Bestandsaufnahme der deutschen Friedensbewegung. Dabei wird zunächst die Doppelgeschichte der Friedensbewegung in Ost- und Westdeutschland umrissen, sowie die Entwicklung seit 1989. Der Text gibt einen Überblick über die Bandbreite von Organisations- und Aktionsformen und unterscheidet idealtypisch drei Handlungsschwerpunkte der zurückliegenden Jahrzehnte. Im letzten Teil wird beleuchtet, wie die Friedensbewegung auf den russischen Angriffskrieg reagiert hat und was aktuelle Herausforderungen der Bewegung sind.
Die Zukunft des Multilateralismus und der OSZE und die Bedeutung der Zivilgesellschaft
Authors: Greminger Thomas , Holewiak Klaudia Anna
Published: November 2022

Die Welt steht vor einer unvorhergesehenen Krise mit dem Auftreten mehrerer regionaler Konflikte und dem Einmarsch Russlands in die Ukraine. Vor diesem Hintergrund erörtert dieser Artikel, wie Europas Sicherheit sich nach dieser Krise entfalten könnte. Er unterstreicht hierbei, dass die gegenwärtigen Herausforderungen für den europäischen Sicherheitsdialog die europäischen Staaten dazu auffordern, gemeinsam mit der OSZE die diplomatischen Beziehungen und die Zusammenarbeit zu stärken. Die Situation in Europa und dessen enge zwischenstaatliche Verflechtung betont zudem die Notwendigkeit und den Bedarf an Reformen, besonders im Sicherheitsbereich. Ferner ist es von entscheidender Bedeutung, sich in den Friedensbemühungen auf historische Entwicklungen zu stützen. In Anbetracht der aktuellen Situation werden die Lehren aus den Helsinki-Vereinbarungen und die Stärkung bestehender Rahmenwerke sich als entscheidend erweisen bei der Förderung von Frieden sowie von regionaler und internationaler Sicherheit und Zusammenarbeit. Die Rolle der zivilgesellschaftlichen Organisationen ist hierbei von zentraler Bedeutung, da sie eine Fülle wertvoller Informationen und Forschungsanalysen bereitstellen, die einen entscheidenden Beitrag dazu leisten, Anliegen von Konflikten betroffener Regionen und der internationalen Gemeinschaft als Ganzes zu enthüllen und zu berücksichtigen.
The loss of Jê nominal verbs in Panará
Authors: Bardagil Bernat
Published: November 2022

In Jê languages, verbs appear in a non-finite form that fulfills a double function: licensing marked TAME semantics in main clauses, and licensing embedded clauses. However, the Panará language lost its non-finite verbal form. This paper examines Panará verbs from both a synchronic and diachronic angle, and in a broader comparative approach with regards to the morphosyntactic behaviour of verbs in the other Jê languages. The main claim is that the non-finite forms prevalent in the Jê family underwent a reanalysis in Panará, resulting in fully finite clauses in all environments.
Regulation of the photovoltaic performance of TiO2@MAPbI3 core–shell nanowire arrays
Authors: Cheng Li , Xing Shulin , He Jizhuang , He Yunfei , Li Jiahua , Fu Chunlin
Published: November 2022

To further the exploration of perovskite nanowires, TiO2@CH3NH3PbI3 (TiO2@MAPbI3) core–shell nanowire arrays were successfully prepared via immersion and spin-coating methods. Because the shell thickness has a significant influence on the carrier transport capacity of nanowire arrays, different shell thicknesses were obtained by changing the precursor concentration. Subsequently, the relationship between the precursor concentration and shell thicknesses and the resulting properties of the nanowire arrays were investigated. The X-ray diffraction results showed that the prepared nanowire arrays consisted of only MAPbI3, TiO2, and fluorine-doped tin oxide phases, with no impurities. From the scanning electron microscopy and energy dispersive X-ray spectroscopy results, the MAPbI3 shell material was successfully coated onto the core layer of the TiO2 nanowire arrays. In addition, the average size of the core–shell nanowire arrays and the shell thickness were obtained using scanning electron microscopy and related software analyses. The results showed that the shell thickness was the largest (40 nm) when the precursor concentration was the lowest (0.025 mol L−1). Ultraviolet–visible spectroscopy showed that when the precursor concentration was 0.025 mol L−1 and the shell thickness was the largest, the nanowire array exhibited the highest absorbance and the smallest band gap, which is conducive to generating more carriers and improving its photovoltaic performance; the J–V curve showed the highest photoelectric conversion efficiency at this concentration and shell thickness. Therefore, it can be inferred that the shell thickness may affect the optical and photovoltaic properties. The relationship between the precursor concentration and thickness as well as the influence of this relationship on the properties of core–shell nanowire arrays should be further explored, to establish a foundation for the use of perovskite nanowires in the photovoltaic field.
A study of melting temperatures in bismuth and antimony
Authors: Kuchhal Piyush , Dass Narsingh
Published: November 2022

We studied the melting temperatures of bismuth and antimony as a function of pressure in this paper because, unlike other solids, melting temperatures are found to fall with increasing pressure. A phenomenological model is proposed to represent the melting temperature as a function of pressure in both solids using Lindemann’s criterion. The computed results are found to be very close to the experimental data. The average absolute percentage relative deviation (AARD%) in bismuth is 0.012, 0.038 in antimony (set-1) and 0.128 in antimony (set-2). Furthermore, the minimum condition is obtained, which gives the pressure at the minimum melting temperature.
Performance analysis of 2λ × 160 Gbps optical single sideband (OSSB) generation in polarization division multiplexed (PDM) QPSK based satellite wireless optical systems (SWOS)
Authors: Garg Raveena , Kaur Gurpreet , Kumar Naresh
Published: November 2022

Capacity enhancement in satellite wireless optical systems (SWOS) systems is an ultimate task to accomplish due to ever-increasing internet services and it can be achieved by incorporating polarization division multiplexed (PDM) quadrature phase shift keying (PDM-QPSK). Herein, 2λ × 160 Gbps intersatellite optical wireless communication (IsOWC) system is proposed using PDM-QPSK. Spectral efficiency is prime requirement to enhance the performance of system and therefore, a suppression of optical single sideband (OSSB) in PDM-QPSK carrier spectrum is performed by employing fiber Bragg grating with 0.99 reflectivity. Proposed system is investigated in terms of log BER and error vector magnitude percentage (EVMP) at varied SWOS distances. Further, effects of the digital signal processing (DSP) in the receiver are analyzed by considering and neglecting the module. Results revealed that suppression of sidebands and employment of DSP enhance the system performance and competent to cover 52,000 km SWOS distance.
Caesar’s First Consulship and Rome’s Democratic Decay
Authors: Rafferty David
Published: November 2022

This article argues for the usefulness of recent scholarship on democratic decay (especially in the disciplines of political science and constitutional law) for explaining the breakdown of Rome’sres publicaduring the 50s BCE, with a particular focus on Steven Levitsky and Daniel Ziblatt’s “How Democracies Die” (2018). Using “democracy” in the neo-republican sense of government free from domination, Levitsky and Ziblatt show how the actions and reactions of political actors can damage a political system without any intention to overthrow it. This article combines their insights with concepts from Christian Meier’s “Res Publica Amissa”(2nd edition 1980) to analyse Caesar’s first consulship in 59 BCE. After explaining how the theory can responsibly be applied, it closely examines the major events of the year, especially the contest over the agrarian law. Caesar’s actions throughout the year demonstrate Levitsky and Ziblatt’s warning signs for a potential authoritarian, as do those of the opposition. This analysis helps us more clearly understand just how the events of “the consulship of Julius and Caesar” (Suet. Iul. 20.2) contributed to Rome’s democratic decay in succeeding years. The article connects to much recent work on late-republican political institutions. It also helps make this dramatic period of Roman history comprehensible to political scientists by analysing it in their own theoretical terms.
Not Only “invincible in arms, a glorious warrior” (Plut. Pyrrh. 11.8). Pyrrhus and the Administration of the Epirote Kingdom
Authors: Domínguez Adolfo J.
Published: November 2022

In relation to King Pyrrhus of Epirus, a great number of studies have analysed his different military campaigns, but very few have focused on the political and economic aspects of his reign. Based on a series of references taken from literary accounts, we seek to demonstrate how the internal organisation of the Kingdom of Epirus under Pyrrhus was similar to that of other contemporaneous Hellenistic kingdoms, replete with a Court consisting of a large number of the king’s friends and companions. Using certain archaeological evidence, especially funerary remains, we seek to reflect the existence of this Epirote élite in material terms. The literary tradition bears witness to an interest in agriculture and livestock farming during Pyrrhus’ period, although the accounts handed down to us provide little detail. Once again, archaeology enables us to provide corroborating evidence. In this respect, we focus on the existence of a series of fortified rural residences distributed in irregular manner throughout Epirote territory, which are interpreted as being those of the members of this aristocratic élite, who used these fortified enclosures as centres of exploitation for their lands and as symbols of their power and prestige. As comparative points of reference that enable us to understand these processes, we provide various examples from neighbouring Macedonia, a kingdom with which Epirus maintained close links, especially as of the mid-fourth century B.C., which appears to be the period in which many of these new developments also began to emerge in Epirus, reaching their culmination during the reign of Pyrrhus.
The Fame of Trajan: A Late Antique Invention
Authors: Hekster Olivier , Betjes Sven , Heijnen Sam , Iannantuono Ketty , Jussen Dennis , Manders Erika , Syrbe Daniel
Published: November 2022

Trajan’s status as a model emperor is perhaps most famously expressed in Eutropius’ catchphrase “More fortunate than Augustus, better than Trajan” (Eutr. Brev. 8.5.3). Modern scholarship has similarly stressed Trajan’s exemplary status, assuming that Trajan’s virtues were already a point of departure by which to measure second- and third-century emperors. This article challenges that notion; it argues that Trajan’s status as a model emperor was a late-antique literary construct. Trajan only entered the repertoire of exemplary emperors during the course of the fourth century to become the model emperor in the very late-fourth- and early-fifth century. This development depended on the historical context and ideological demands, as well as on the availability of the then-existing material discussing and depicting the historical Trajan.