bluuebunny/crossref_metadata_2025 huggingface dataset:
Impact of Learning on Ordering Policy for Deteriorating Imperfect Quality Items with Promotion Dependent Demand, Partial Trade-Credit and Shortages
Authors:   Research Scholar, Department of Mathematics, The Gandhigram Rural Institute- Deemed to be University, Gandhigram, 624 302, Tamil Nadu, India, Priyadharshini A Ruba , Jayasankari C , Uthayakumar R
Published: June 2024

Objective: The objective of the developed inventory model is to find the optimal solution for the retailer, while performing inspection for the defectives, and also to offer partial credit periods, where shortages are allowed. Methods: To derive the required solution which benefits the retailer, the partial derivatives method for the decision variables where used and to solve the complicated differential equations the necessary and sufficient conditions has been derived and the theorem and its proofs are given. Findings: In this research findings, the optimal credit period policy and promotional effort dependent demand pattern that offers more profit to the retailer, provided with inspection policy for finding defective items in the lot. Shortages are allowed and completely backordered. Numerical examples and sensitivity analysis are performed to verify the reliability of the developed model. Novelty: This study presents a new model wherein the retailer offers credit period and with shortages that will apt the real life situation as the model developed here is for deteriorating items, which is inevitable to maintain the perfect system. Keywords: Multi­Echelon Inventory Model, Sustainability, Shortages, Credit Period Offers, Learning In Inspection
Isomorphism on Complex Fuzzy Graph
Authors:   Associate Professor, PG & Research Department of Mathematics, Jamal Mohamed College (Autonomous) (Affiliated to Bharathidasan University), Tiruchirappalli, 620 020, Ismayil A Mohamed , Azhagendran N
Published: June 2024

Objective: To investigate isomorphism between two complex fuzzy graphs and prove it is an equivalence relation. The major objective of this research paper is to elucidate weak and strong isomorphism, and the study also endeavours to look at the complement of complex fuzzy graphs. Methods: Isomorphism is examined by comparing the membership values of nodes and arcs (both amplitude and phase). The same technique also proves further validation of the equivalence relation, which is also proven by the same technique. This criterion helps us to identify and formalise the isomorphic relationship between complex fuzzy graphs. Findings: This study demonstrates that isomorphism in complex fuzzy graphs allows for consideration of graph structures' differences and similarities. It provides for a better understanding of significant connections between complex fuzzy graphs. Novelty: By offering an elaborate perception of the idea of isomorphism in complex fuzzy graphs, this work advances the discipline. It seeks a better understanding of the complexities of equivalency determination for complicated structures, as well as the application of isomorphism theory to complex fuzzy graphs. Keywords: Complex fuzzy graph, Homomorphism, Isomorphism, Partial order relation, Self complementary
Discrete Labeling of Graphs
Authors:   Associate Professor, Department of Mathematics, St. Mary’s College (Autonomous), Thoothukudi, Tamil Nadu, India, Affiliated to Manonmaniam Sundaranar University, Abishekapatti, Tirunelveli, 627 012, Tamil Nadu, India, Tharani A Punitha , Saradha P
Published: June 2024

Objectives: To introduce a new type of labeling called Discrete Labeling. This labeling aims at providing the maximum output whenever the inputs are distinct with rational distribution of neighbours thereby exhibiting the stronger form of Cordial labeling. This work serves as an aid in decision-making. Methods: The discrete labels 0 and 1 are cordially assigned to the vertices such that the edges receive labels depending on the incident vertex labels using EX-OR operation with the condition that for every vertex the cardinality of neighbours labeled 0 and 1 differs by at most 1. Findings: This study proposes the discrete labeling of some standard and special graphs. Also it provides the cases for which certain path, star and cycle related graphs admit discrete labeling. Novelty: This labeling uses EX-OR operation which reduces the complexity of having two swords in one sheath. Apart from keeping the distinct vertex labels and edge labels difference minimal, the cardinality of the neighbouring labels of every vertex is also taken into account. Keywords: Graph Parameters, Discrete, Trees, Cycle, Complete Graphs
Generalizing TCCD-Number For Power Graph Of Some Graphs
Authors:   Department of Mathematics, Gandhigram Rural Institute - Deemed to be University, Gandhigram, Tamil Nadu, Kaviya S , Mahadevan G , Sivagnanam C
Published: June 2024

Objective: Finding the triple connected certified domination number for the power graph of some peculiar graphs. Methods: A dominating set with the condition that every vertex in has either zero or at least two neighbors in and is triple connected is a called triple connected certified domination number of a graph. The minimum cardinality among all the triple connected certified dominating sets is called the triple connected certified domination number and is denoted by . The upper bound and lower bound of for the given graphs is found and then proved the upper bound and lower bound of were equal. Findings: We found the (TCCD)-number for the power graph of some peculiar graphs. Also, we have generalized the result for path, cycle, ladder graph, comb graph, coconut tree graph, triangular snake, alternate triangular snake, quadrilateral snake and tadpole graph. Novelty: The triple connected certified domination is a new parameter in which the certified domination holds the triple connected in induced . Keywords: Domination Number, Power Graphs, Triple Connected, Certified Domination, Triple Connected Certified Domination
Impedance (xCELLigence) v1
Authors: Russell Amanda , R Kennedy Philippa
Published: June 2024

This assay is used as a readout of NK cell cytotoxicity of adherent tumor cell lines. Tumor cells are seeded onto a 96-well gold-coated plate. As tumor cells adhere to the plate and proliferate, the flow of electrons is impeded across microelectrodes. Since NK cells minimally impact impedance, tumor cell survival is inferred from this impedance of electron flow. NK cells and drugs are added after 24 hours and a measure of killing is determined by reduced impedance, indicating tumor cell death. Continuous impedance data acquisition produces real-time killing curves.
SCRMshaw: supervised cis-regulatory module prediction for insect genomes v1
Authors: Asma Hasiba
Published: June 2024

As the number of sequenced insect genomes continues to grow, there is a pressing need for rapid and accurate annotation of their regulatory component. SCRMshaw is a computational tool designed to predict cis-regulatory modules (CRMs) in the genomes of various insect species (Kantorovitz 2009; Kazemian 2011; Asma and Halfon 2019; Asma 2024). One of the key advantages of SCRMshaw is its accessibility. It requires minimal resources—just a genome sequence and training data from known Drosophila CRMs, which are readily available for download. Even users with modest computational skills can run SCRMshaw on a desktop computer for basic applications, although an HPC cluster is recommended for optimal results. SCRMshaw can be tailored to specific needs. Users can employ a single set of training data to predict CRMs associated with a particular gene expression pattern, or utilize multiple sets to provide a rough regulatory annotation for a newly-sequenced genome. This protocol provides an update to the protocol in Kazemian and Halfon (2019) and incorporates modifications introduced in Asma and Halfon (2019) and Asma et al. (2024).
OSU TriState SenNet Processing and Storing of Explanted IPF Lungs v1
Authors: D. Stacey Sean , F. Reader Brenda , Rosas Lorena , Peters Victor , L Mora Ana , Rojas Mauricio
Published: June 2024

This protocol describes the processing and storing of explanted idiopathic pulmonary fibrosis (IPF) lungs by the Comprehensive Transplant Center (CTC) Human Tissue Biorepository before arrival at the TriState SenNet Biospecimen Core of The Ohio State University that functions as a part of the Cellular Senescence Network Program (SenNet). This protocol is based on the CTC Human Tissue Biorepository's standard operating procedure established for tissue collection for explant and donor samples. We follow routine laboratory specimen processing guidelines to ensure the highest biospecimen quality.
Nanodrop Lite (Shared Equipment Lab) v1
Authors: M Weerasuriya Nimalka
Published: June 2024

How to use the Nanodrop Lite.
OSU TriState SenNet Processing and Storing of Normal Donor Lungs v1
Authors: D. Stacey Sean , F. Reader Brenda , Rosas Lorena , Peters Victor , L Mora Ana , not provided mauricio.rojas
Published: June 2024

This protocol describes the processing and storing of normal donor lungs by the Comprehensive Transplant Center (CTC) Human Tissue Biorepository before arrival at the TriState SenNet Biospecimen Core of The Ohio State University that functions as a part of the Cellular Senescence Network Program (SenNet). This protocol is based on the CTC Human Tissue Biorepository's standard operating procedure established for tissue collection for explant and donor samples. We follow routine laboratory specimen processing guidelines to ensure the highest biospecimen quality.
Assessing Pyrene Impact on Precopulatory Behaviour: A Cost-effective Time-to-Event Experiment with Parhyale hawaiensis v1
Authors: Lawan Ibrahim
Published: June 2024

Understanding the impact of environmental contaminants on chemosensation is crucial for assessing the ecological fitness of aquatic organisms. Here, we present a step-by-step protocol for investigating the chemosensory responses of Parhyale hawaiensis to precopulatory activity following exposure to Pyrene (Pyr), a model polycyclic aromatic hydrocarbon (PAH). We use a time-to-event experimental design to assess the organism's response time to its mating partner in a 70ml petri dish setup under different exposure conditions. This protocol offers a simple approach for conducting cost-effective behavioural ecotoxicology and contributes to our understanding of the interactive effects of contaminants on aquatic organisms.
Filter trap assay for the detection of alpha-synuclein aggregation v1
Authors: S Sitron Cole
Published: June 2024

This protocol describes an assay that detects aggregated alpha-synuclein in cell lysates.
Modeling Growth and Photoadaptation of Porphyridium purpureum Batch Culture
Authors: Lelekov A.S. , Klochkova V.S.
Published: June 2024

The work focuses on mathematical modeling of linear growth marine red algae Porphyridium purpureum batch culture under various surface irradiation. Before starting the batch culture P. purpureum was maintained for 3–5 days in turbidostat, which allowed the culture to adapt to a given light intensity. On each batch curve the maximum specific growth rate and maximum productivity are determined by approximating the exponential and linear growth phases with the appropriate equations. It is taken into account that at the beginning of the linear growth phase the integral light absorption coefficient, calculated from the true absorption spectrum in PAR range, exceeded 50 %. It is shown that with light intensity increase from 15 to 227 µmol photons m–2·s–1 the maximum specific growth rate increased from 0.31 to 1 day–1, the maximum productivity increased from 1.32 to 16.38 g DW m–2·day–1. Mathematical modeling of the linear growth of P. purpureum batch culture have showed that at any light intensity the specific growth rate is determined by the surface illumination, the light absorption coefficient and chlorophyll a concentration. The concept of reduced irradiation – the amount of absorbed light energy per chlorophyll a – was introduced. A linear dependence of the specific growth rate on reduced irradiation is given. The tangent of the angle of line slope is determined by the organization of the key multi-enzyme complex («metabolism bottleneck»). Parameters of this complex depend on the cells photoadaptation degree. For the first time a quantitative relationship between multi-enzyme complex parameters, light intensity and the chlorophyll / P700 ratio was established.
Mapping Arab-Israeli Conflict : A Bibliometric Analysis
Authors: Lokman Ainul Asyraf
Published: June 2024

The Arab-Israeli conflict and the circumstances in the region were significantly impacted by the 1967 conflict, often known as the Six-Day War. This study attempts to offer recommendations by exploring the trend and characteristics of Arab-Israeli conflict as the conflict become increasingly multiplex. Thus, the main objective of this study is to visualize trends in research on Arab-Israeli conflict from 1967 to 2022. This study examined quantitative and qualitative bibliometric data using escriptive and visual methods. The bibliometric data was retrieved from the Scopus database (the largest inter-disciplinary database in social sciences), and the authors ran a number of analyses on it using Biblioshiny via the R-Studio and VOSviewer software. As a result, this article will shed light on the most recent trend and features of Arab-Israeli research published in the Scopus database. The analysis shows that Israel and the United State of America (USA) have become the top countries that have played a major role in creating collaborative research on Arab-Israeli conflict. Furthermore, the study highlights the increase in publication on this topic over the past decade and the growing interdisciplinary approach among scholars including psychological aspect and normalization aspect in terms of conflict management. To the authors’ knowledge, this is the first bibliometric study of Arab-Israeli conflict materials in Scopus. As a result, it will assist academics in broadening and deepening their studies on Arab-Israeli relations, so raising their chances of attaining a permanent peace.
Discourse of Islamic Educational Philosophy on Islamic Educational Psychology in Islamic Education
Authors: Pranajaya Syatria Adymas
Published: June 2024

The purpose of writing a discourse of the Islamic educational philosophy on Islamic educational psychology in Islamic education is to critically describe the discourse of these two scientific studies in the world of education. The method in this study is library research through library data relevant to educational philosophy, Islamic educational philosophy, and Islamic educational psychology. The analysis technique in this study is thematic analysis. The results of this study indicate that the Islamic educational philosophy towards the Islamic educational psychology is the core of educational philosophy that views education as a process of humanizing students as a person or a group of people who increase their human potential, so that they are able to develop and actualize themselves with all the original potential (fitrah) that exists in them psychologically. The values of fitrah have been attached to Islamic education, including that educators in educating their children must prioritize the philosophy of physical and psychological humanity, such as love (QS. Ali Imran: verse 31, QS. al-Hujaraat: verse 7, QS. at-Taubat: verse 103), compassion (QS. ar-Rum: verse 21, QS. Maryam: 96, QS. al-An’am: 12 and 54, QS. al-Hadid: 27), good teaching (QS. Al-Ahzab: 21, QS. An-Nahl: 125, QS. Al-Mujadalah: 11, QS. at-Taubah: 122), friendship (QS. Az-Zukhruf: 67, QS. Ali-Imran: 52 and 104), upholding justice (QS. Luqman: 17, QS. an-Nisa: 135, QS. An-Nahl: 76, QS. Al-Maidah: 8), always strive to obtain goodness (QS. al-A’raf: 56, QS. al-Isra’: 7, QS. al-Maidah: 100), so that in education there is two-way communication or even multi-directional interaction or transactions (QS. al-Baqarah: 133, QS. as-Saffat: 102).
The Forming of the Modern Legal Terminology in Hebrew: Methods and Other Legal System Influence
Authors:   University of Wroclaw, Wroclaw, Poland, YAKOVLEVA Olga , TSVIETKOVA Yulianna ,   Taras Shevchenko National University of Kyiv, Kyiv, Ukraine
Published: June 2024

The article is dedicated to the peculiarities of the legal terminology formation, which took place in the process of the restoration of the Hebrew language and its becoming the official state language of the modern Israel. The legal system of Israel has been created during XX century, after near two-thousand-year period of its existence without own state, being limited to the small community’s common and religious law in different languages only. Thus, creation of the own state has demanded not only to adapt the legal institutes, but to develop new actual terminology in the new official state language. But the terminology complex of the Hebrew was based on the ancient language sources, so creation or adapting of the classic Hebrew words for the definition of the modern legal terms became a great scientific challenge. In the article we conclude, that new lexemes were not created in the process of the Israel legal terminology formation, but the old texts words were chosen, usually with some rethinking and reinterpretation of its meanings. This approach provides the possibility to avoid direct borrowing of the terms, which is a typical process in the reception of law in other states. Despite the fact that, in addition to the English Common Law, the formation of Israel’s legal system was influenced by the Ottoman and Romano-Germanic law, concepts from the English legal system were taken as the basis for the selection of many basic terms. The terms creation was not limited to formal denomination only. Often the process becomes more substantive, noticing the etymology, the content of the legal institute and the mechanisms of the practical law-enforcements. After this deep scientific work of the linguists and lawyers Hebrew terminology of the Israel legal system fully expresses the content and the scope of the concepts of the relevant legal institutes.
Conceptual Dichotomy “Word of God – Human Word” in the Biblical Discourse
Authors:   Ternopil Volodymyr Hnatiuk National Pedagogical University, Ternopil, Ukraine, ODYNTSOVA Halyna , KONDRATIEVA Tetiana ,   Ternopil Volodymyr Hnatiuk National Pedagogical University, Ternopil, Ukraine
Published: June 2024

The article deals with the study of the concept “word” as a basic one in the Holy Scripture. The Bible as a precedent text has always attracted researchers’ attention and still remains topical. It provokes interest as it renders sacral conceptual paradigm to the fullest. The article deals with cognitive linguistic modeling of the mentioned concept in the Biblical discourse, considering binary opposition “word of God – human word”. Cognitive meanings of the nuclear and peripheral concept zones, which are represented in the forms of notional, figurative and evaluative information, have been revealed in the course of study. Its nucleus contains factual and conceptual information, within which two components are characterized: linguistic and theological. The nomens “group of sounds”, “a language unit”, “speech”, “language”,”talk” and “conversation” represent the linguistic nature of a word. The lexemes “Logos”, “Gospel”, “the expressed or manifested mind and will of God”, “Jesus Christ” and “Holy Scripture” verbalize the theological component. A range of senses of the concept “word” has been singled out and analyzed, which often constitute whole microcontexts in the Biblical discourse. The peripheral zone of the concept “word” has been analyzed, that is represented as imagery and value information. The value information has been constructed on the opposition of the positive and negative connotations of the concept “word”. The imagery information naturally complements the notional one mostly by using the conceptual metaphor. The concept “word” in the Biblical discourse has been interpreted through comparison of dichotomies “sacral – profane”, “eternal – temporary”, “ideal – real”, “transcendental – immanent”, which manifest the extreme opposition “Word of God – human word”.
The Verb in the Linguistic and Conceptual Worldviews of English Language Speakers
Authors:   Ivan Franko National University of Lviv, Lviv, Ukraine, DILAI Iryna
Published: June 2024

The paper studies the peculiarities of mental representations of the verb in the conceptual worldview and their reflection in the linguistic worldview of English language native speakers. Special attention is paid to the etymology and meaning of the word “verb” in the English language. In particular, its connection with the meaning “word” in general, which is manifested in the corresponding derivatives, is clarified. A tendency to define the verb through its syntactic function in scientific literature has been revealed. The key role of the predicate-argument structure, which reflects the linguistic worldview of English language native speakers, has been established. At the same time, the conceptual structure of the verb meaning and its mental representations shed light on the place of the verb in the conceptual worldview of English language native speakers. In the naive worldview of the English speakers, a tendency to associate the verb with an action or an act can be observed. High productivity of verbification in present-day English, as well as the overall high saturation of verbs in the English language corpora, estimated at 10.86 per cent, testify to the significance of the verb in English. The corpus analysis has been conducted based on the Corpus of Contemporary American English (COCA), the British National Corpus (BNC), the Strathy Corpus of Canadian English, and iWeb Corpus of modern web communication. The total distribution of verbs across the aforementioned corpora does not reveal any substantial variation. Nonetheless, the corpus data provide illuminating insights into the worldview of the native speakers of English. The prospects of further research in this direction lie in the construction of a mental model of the English verb, which would integrate the approaches to verb semantics within different modern frameworks, employing both experimental findings and empirical corpus data.
Küresel Ekonomi Politika Belirsizliği (GEPU) Endeksi ile Bitcoin Arasındaki İlişkinin Analizi
Authors: Kılıç Ethem
Published: June 2024

Bu çalışmanın temel amacı küresel ekonomi politika belirsizliği (GEPU) endeksinin bitcoin üzerindeki etkisini incelemektir. Değişkenler arasındaki ilişkiyi ortaya koymak için Ağustos 2010 – Mart 2023 dönemine ait veriler kullanılmıştır. Küresel ekonomi politika belirsizliği (GEPU) endeksi ile bitcoin arasındaki ilişkiyi açıklamak için normal dağılmama durumunu dikkate alan RALS eşbütünleşme testleri kullanılmıştır. Değişkenlerin I(1) düzeyinde durağanlaştığı saptanmış, daha sonra RALS-ADL ve RALS-EG2 testleri uygulanmıştır. RALS-ADL ve RALS-EG2 eşbütünleşme testleri sonuçlarına göre GEPU endeksi ile bitcoin arasında eşbütünleşme ilişki olduğu tespit edilmiştir. Modelin uzun dönem katsayısına göre GEPU endeksindeki yüzde bir birimlik artış bitcoini 0.092 oranında artırdığı saptanmıştır.
Awareness among undergraduates about State Dental Council and Medico - legal issues - Stratified cluster random sampling survey
Authors: Rani Anusha , Sharma Dixitha
Published: June 2024

To assess the level of awareness on State Dental Council and Medico - Legal issues among Undergraduate students.

This survey was performed by online distribution of questionnaires in few Dental colleges for final years and internship students In Andhra Pradesh state. The questionnaire consisted of random questions based on Functional, structural aspects of State Dental Council and some prevention-based questions on Medico-Legal issues. The answers were either multiple choice or closed end (yes/no) and were designated with one point for every right answer chooses.

A total of 625 respondents completed the questionnaire out of which 350 being intern students and 275 being final year students. Overall, awareness was medium when compared based on level of awareness, year of study and gender variation.

The level of awareness is medium among the respondents. However, the knowledge is comparatively high among intern students than final years students. Based on gender, slight variation is observed; females had more awareness compared to males.
Re-intervention in restorative dentistry: Knowledge and attitudes of senegalese dentists
Authors: Diop Elhadji Cyre , Diene Mor Nguirane , Niang Seydina Ousmane , Faye Babacar
Published: June 2024

Replacing or repairing a defective restoration has become a daily practice in dentistry. It is therefore necessary to know how to evaluate a restoration to decide whether or not to re-intervene and then to choose whether to replace, repair, or refrain from doing so by setting up a monitoring system. The best-known evaluation criteria accepted by the scientific community are the modified Ryge / USPHS criteria and the FDI criteria.

In Senegal, no such study has been carried out, and it was with this in mind that our study was carried out, involving 158 dental surgeons. The results showed a predominance of men (70.89%). The average age was relatively young at 37. The study confirmed that re-intervention is common practice among the dentists surveyed: the majority (77.72%) had done a re-intervention less than a week before the survey. The most common reason encountered by dentists for their last re-intervention was fracture of the tooth or restorative material with a rate of 36.71%, then we have caries recurrence and advanced decay and wear with the same rate of 17.09%, followed by pain or hypersensitivity with a rate of 16.46%.

After diagnosis, 73% replaced the restoration deemed defective, versus 22% who chose to repair the restoration. Clinical evaluation criteria were used by only 12.66% of the sample. The majority, 74.05% of practitioners, take into account the benefit/risk/cost ratio.

The results of this study show the limits of dental surgeons' knowledge in re-intervention, as well as the lack of codification of parameters related to this practice. It is therefore necessary to develop training programs and teaching units for both initial and continuing training.
Incision and drainage as mainstay therapy in antibioma: A case report
Authors: Fathima S  , Suchithra M S  , Zarina A Rita , Jaziya Z
Published: June 2024

Antibioma is a chronic sterile, tough fibrous abscess formed commonly due to prolonged and inappropriate use of antibiotics for infections, without facilitating proper drainage of the pus. It is a localized swelling which is painless, smooth, non-tender and firm on palpation. It is only after the abscess has been incised, the body defence mechanism and antibiotic can eradicate the infection by releasing pressure, increasing blood circulation and oxygen to the anaerobic environment. Here, a rare case of antibioma in the neck of an 8 year old male child who had undergone extraction of an offending tooth to eradicate the infection. However, inadequate drainage of the abscess and lack of proper postoperative follow-up led to persistence of residual infection.
Irony of mandibular molar: A case series if management of radix
Authors: Tarnach Chetna , Singh Aiana , Garg Nisha , Kumar Sandeep , Grover Deepak
Published: June 2024

Endodontics is a comprehensive knowledge of the intricate nature of the root canal system is paramount. In case series we had investigates the intricate landscape of managing radix entomolaris, an additional root often encountered in mandibular molars. Success in endodontic treatment hinges on precise diagnosis, anatomical understanding, and meticulous procedural execution. The enigmatic nature of radix entomolaris introduces complexities due to variations in root canal morphology. Through meticulously documented case reports, we elucidate the diagnostic methods and successful endodontic procedures employed in two distinct patient cases presenting with symptomatic irreversible pulpitis.
Effectiveness of aromatherapy in reduction of dental anxiety in pediatric dental patients: A systematic review
Authors: Sachdev Sanpreet Singh , Padawe Dimple , Wankhade Ajinkya , Takate Vilas , Dighe Kishor , Agrawal Arushi
Published: June 2024

In recent years, various researchers have attempted to utilize Aromatherapy for allaying dental anxiety in pediatric patients. The present systematic review aims to comprehend the efficacy of aromatherapy in reducing dental anxiety in pediatric patients, exploring different aromatherapy agents, dispersion methods, and their anxiety-relieving capacities.

A systematic search was performed in the following databases: MEDLINE (Ovid), Pubmed, Pubmed Central, Web of Science Citation Index Expanded (SCIEXPANDED), and Google Scholar using the key terms “Aromatherapy” AND “Pediatric” OR “Children” AND “Dental Anxiety” OR “Fear” to identify articles published in the English language without any restriction for the time of publication.

A total of nine randomized controlled trials were identified that assessed various essential oils such as lavender, orange, and lemongrass for aromatherapy in pediatric patients during dental treatment. Most of these studies employed aromatherapy using a diffuser during non-pain-promoting dental treatments in children of 6 to 9 years of age.

Aromatherapy is an effective non-pharmacological and non-invasive modality for reducing dental anxiety in pediatric patients which is free of adverse effects. However, there's a need for standardized methods of dispersion and clearer guidelines for oil posology
Non-destructive testing of non-steroidal anti-inflammatory drugs using near-field infrared spectroscopy method
Authors:   Vladimir State University named after Alexander and Nikolay Stoletovs, Emelyanov Oleg E. , Amelin Vasiliy G. ,   Vladimir State University named after Alexander and Nikolay Stoletovs, The Russian State Center for Animal Feed and Drug Standardization and Quality, Tretyakov Аleksey V. ,   The Russian State Center for Animal Feed and Drug Standardization and Quality
Published: June 2024

The use of near-infrared spectroscopy for quality control of nonsteroidal anti-inflammatory drugs (NSAIDs) in blister packs is demonstrated. NSAIDs with the active ingredients ibuprofen, diclofenac, naproxen, etoricoxib, acetylsalicylic acid and meloxicam have been studied. IR spectra have been recorded using a Frontier FTIR spectrometer with a NIRA attachment, used to collect diffuse reflectance spectra of solids. Processing and visualization of the study results has been carried out using chemometric algorithms – principal component analysis (PCA), hierarchical cluster analysis (HCA) and partial least squares regression (PLS). It is shown that using these algorithms it is possible to identify drugs by their manufacturer and determine the concentration of active substances. In the PCA method, the points corresponding to the samples of the analyzed tablets are located in separate quadrants depending on their manufacturer. The use of hierarchical cluster analysis (HCA) made it possible not only to differentiate the analyzed tablets by manufacturer, but also to determine the content of the active substance in them. “Measured-predicted” calibration models have been constructed, the values of the root mean square residual of calibration (RMSEC) did not exceed 6.28 mg. The relative discrepancies between the values obtained during the analysis and those assigned correspond to the permissible deviations established by order of the Ministry of Health of the Russian Federation dated October 26, 2015 no. 751n. The duration of the analysis was 7–10 min.
Description and investigation of chemical interaction in the Li+,Na+||F-,Cl-,Вг- system
Authors:   Samara State Technical University, Burchakov Alexander V. , Garkushin Ivan K. ,   Samara State Technical University, Dvoryanova Ekaterina M. ,   Samara State Technical University, Emelyanova Ulyana A. ,   Samara State Technical University, Zamaldinova Alena I. ,   Samara State Technical University, Chugunova Marina V. ,   Institute “REAVIZ”
Published: June 2024

The use of melts in various fields of industry and scientific research is based on the study of the properties of melts and the chemical processes occurring in them. In modern engineering and technology, a significant number of processes are associated with the use of mixtures of lithium and sodium halides as mixtures that accumulate heat, as electrolytes for medium-temperature chemical current sources. Therefore, the interest in the study of systems involving such systems is continuously increasing. The paper calculates the thermal effects of exchange reactions and Gibbs energy in ternary reciprocal systems of a quaternary reciprocal system Li+,Na+||F-,Cl-,Br-, as well as for a mixture corresponding to the central point of the conversion line. The conversion line is obtained as a result of the intersection of unstable and stable triangles. In accordance with the calculation data, it is shown that the conversion lines in the skeleton of the compositions intersect at the conversion point K3 with the maximum thermal effect of the reaction equal to the sum of the thermal effects of the reactions (as well as the Gibbs energies) for mixtures corresponding to the conversion points K1 and K2.To confirm the stability of the LiF-NaCl-NaBr triangle linking the stable tetrahedron LiF-NaCl-NaBr-NaF and the stable pentatope LiF-LiCl-LiBr-NaCl-NaBr, the interaction of the initial powder mixture of 50 mol % NaF+25 mol.% LiCl+25 mol.% LiBr has been studied by thermogravimetry. The phase transition temperatures are assigned to the heating curve of the mixture. When heated at a rate of 20 K/min, the exothermic effect begins at 463 oC and ends at 504 оC. For a stable triangle, a melt crystallization scheme of the composition of the central point of the conversion line is shown. Stable crystallizing phases have been confirmed by X-ray phase analysis.
Evaluation of polymeric submicron microcapsule accumulation in cellular and intercellular space of 3D spheroids
Authors:   Saratov State University, Abalymov Anatolii A. , Lomova Maria V. ,   Saratov State University, Novoselova Marina V. ,   Skolkovo Institute of Science and Technology, Gorin Dmitry A. ,   Skolkovo Institute of Science and Technology
Published: June 2024

Multicellular spheroids are three-dimensional in vitro models of organs and tissues. Multicellular spheroids have gained great interest in the field of biotechnology as they are reproducible and mimic real organs and tissues so can be used as test systems for new forms of drugs, allowing minimizing the use of in vivo animal models. Flow cytometry was used to describe the accumulation of submicron polymeric microcapsules in cellular spheroids, which allowed us to identify the main aspects of drug carrier-cell interactions within the spheroid. Spheroids were generated using 4T1 mouse breast cancer cells and healthy L929 mouse fibroblast cells. The arrangement of microcapsules with 300, 500, 1000 nm diameter with biocompatible shells in cell spheroids was evaluated in their intercellular and intracellular spaces.
Institutionalization of Sports for All in Iranian Families
Authors: Kargar Abolfazl , Nazari Rasool , Salimi Mehdi
Published: June 2024

Background: The institutionalization of sports in families plays a significant role in promoting the health of society. This study is aimed to extract effective background factors in institutionalizing sports in Iranian families.  
Methods: The present research follows an interpretive paradigm, inductive logic, and qualitative approach. Besides meta-synthesis approach and interviews were conducted. The research population of the present study included 166 national and international articles presented over the last twelve-year period. After screening the articles, 15 studies were finally selected which met the necessary criteria and were analyzed using the content analysis technique. In the next step, an interview was conducted with 23 experts in "public sports" in a targeted manner using the snowball and theoretical saturation techniques, and finally, the codes of the first and second stages were combined.
Results: Meta-synthesis results led to the identification of 36 indices, the overlap of the codes was compared, and the results showed a reliability of 0.92 After the interview was conducted, 41 indices were identified. The comparison of the results in two time periods showed a reliability of 0.89. Finally, by latent content analysis, summarizing, overlapping, and merging the codes of the previous two steps, 47 influential indices affecting the institutionalization of sports in Iranian families were extracted.
Conclusion: Based on the results of our research it can be concluded that by recognizing, planning, and creating mechanisms for the operationalization of the discovered factors, the process of institutionalizing physical activity in Iranian families will be facilitated.
Medical Record Document Search with TF-IDF and Vector Space Model (VSM)
Authors: Heryawan Lukman , Novitaningrum Dian , Nastiti Kartika Rizqi , Mahmudah Salsabila Nurulfarah
Published: June 2024

The growth of medical record documents is increasing over time, and the various types of diseases and therapies needed are increasing. However, this has not been followed by an effective and efficient search process. This study aims to deal with search problems that often take a long time with search results that are not necessarily as expected by building a search model for medical record documents using the vector space model (VSM) and TF-IDF methods. The VSM method allows retrieval of results that are not the same as the search queries entered by the user but are expected to provide still results relevant to the user's desired needs. The model development process was taken based on the data in the FS_ANAMNESA and FS_DIAGNOSA columns, followed by preprocessing, which consists of deleting blank lines, lowercase, removing punctuation marks, HTML tags, stop words, excess spaces between words, and normalizing typo words, then forming a TF-IDF matrix based on the frequency of occurrence of each word feature, and followed by the calculation of the similarity value of the search query compared to medical record documents based on the cosine similarity formula. The retrieval results were all columns of each existing medical record document and were sorted based on 10 rows with the highest similarity value. The model evaluation results were based on 1000 medical record documents and tested with 20 search queries in this study, which gave an average precision value of 0.548 and an average recall value of 0.796.
Children's Sociodramatic Play: The Imaginative Level and its Narrative Quality
Authors: Glaubman Rivka , Glaubman Hananyah
Published: June 2024

The study examined children's sociodramatic play, hypothesizing that higher imaginal play object-use leads to higher level of play narratives' structure and communication. Two steps were performed to examine this hypothesis: (a) an intervention method in situations other than play; and (b) correlating the level of imaginative objects use in sociodramatic play, and the level of its narrative, measuring two aspects: (1) The quality of the play’s narrative: Its structure, its complexity, and the level of its sophistication; and (2) the level of interactive communication used to construct the narrative. The research examined natural sociodramatic play situations in 16 kindergartens with children of different SES (socio-economic status) backgrounds. Four experimental and 4 control groups of each of two SES levels were sampled. The results indicated that the level of the imaginative object use performance over time, impressively improved in all experimental groups in comparison with the control groups, indicating that the imaginative level of object use was highly correlated with the level of the play narrative and communication. This was found in plays with more complex components and higher structure of the narratives, and more effective communication, in the experimental as compared to control groups, in both low- and medium-SES background. The latter's standard of play was superior as compared to the former, and the gap between groups expanded over time. The results of the study point to the important role of imagination in pretense play narratives and strengthens the potency of narrative theory approach in explaining children’s fantasy in play.
Challenging Issues of Self-Taxation of Citizens in Materials of the Law Enforcement Practice
Authors:   Expert of the Law Enforcement Monitoring Project of the Saint Petersburg State University, Gurinenko Anastasia E. , Izralovsky Nikolay R. ,   Expert of the Law Enforcement Monitoring Project of the Saint Petersburg State University, Kulpin Aleksandr E. ,   Expert of the Law Enforcement Monitoring Project of the Saint Petersburg State University
Published: June 2024

This article presents the results of monitoring law enforcement on the issue of self-taxation of citizens. In the course of the study, the authors established the lack of uniformity of judicial practice at all stages of establishing and fulfilling the obligation to pay self-taxation funds. The authors point to the need to amend the legislation.
Powers of Local Self-Government Authorities in the Fire Safety Sphere: Problems of the Law Enforcement Practice
Authors:   Sky Lawyers, Private International Law Bar Association, Kurochkina Darya S.
Published: June 2024

The article provides an analysis of the execution by local self-government bodies of local authorities and the granting of their state powers in the field of fire safety, as well as certain aspects of bringing municipal officials to responsibility for their failure to fulfill various state powers and powers of local significance.
Combination treatments of patients with chronic rhinosinusitis with nasal polyps
Authors:   Medical and Sanitary Unit „Neftyanik“, Tyumen, 625062, Russian Federation, Dyukova I. A. , Yastremskii A. P. ,   Tyumen State Medical University, Tyumen, 625023, Russian Federation, Volodeev A. V. ,   Medical and Sanitary Unit „Neftyanik“, Tyumen, 625062, Russian Federation,   Tyumen State Medical University, Tyumen, 625023, Russian Federation
Published: June 2024

Targeted therapy has changed the approach to the management of patients with chronic rhinosinusitis with nasal polyps (CRwNP) type 2. However, the treatment of such patients remains one of the urgent problems in otorhinolaryngology, and the search for the optimal combination of treatment methods continues. Objective. To evaluate the effectiveness of combined treatment of patients with CRwNP. Material and methods. 50 patients with CRwNP were treated with dupilumab and mometasone furoate. Patients of the main group underwent endoscopic nasal polypectomy before using these drugs. The results of computed tomography of the paranasal sinuses (Lund-Mackay score and SNOT22 (Sino-Nasal Outcome Test)) were analyzed. Results. A significant decrease in the average SNOT-22 values was revealed in patients of the main group even before the start of dupilumab injections, in subjects from the comparison group, after 8 weeks. The average values on the Lund-Mackay score in patients of the main group were 21.3±2.5 and 7.0±1.1, in the comparison group, 20±2.2 and 7.5±1.3 before and after 6 months of treatment, respectively. Conclusions. Nasal polypectomy before the start of targeted therapy in patients with CRwNP type 2 and severe nasal obstruction helps improve the quality of life according to the SNOT-22 before starting treatment with dupilumab.
Morphological rationale for staged surgical treatment of chronic diseases of lymphoid tissue of pharynx in children
Authors:   Burdenko Voronezh State Medical University, Voronezh, 394036, Russian Federation, Mashkova T. A. , Sorokina M. S. ,   Burdenko Voronezh State Medical University, Voronezh, 394036, Russian Federation, Chirkova I. I. ,   Burdenko Voronezh State Medical University, Voronezh, 394036, Russian Federation,   Derzhavin Tambov State University, Tambov, 392000, Russian Federation,   City Clinical Hospital of Kotovsk, Kotovsk, 393194, Russian Federation, Mal’tsev A. B. ,   Burdenko Voronezh State Medical University, Voronezh, 394036, Russian Federation,   Voronezh Regional Clinical Hospital N 1, Voronezh, 394066, Russian Federation, Shaposhnikova I. V. ,   City Clinical Hospital of Kotovsk, Kotovsk, 393194, Russian Federation, Yamschikov O. N. ,   Derzhavin Tambov State University, Tambov, 392000, Russian Federation,   City Clinical Hospital of Kotovsk, Kotovsk, 393194, Russian Federation
Published: June 2024

Despite the widespread prevalence of combined lesions of the organs of the lymphadenoid pharyngeal ring, the frequent performance of adenoidectomy in pediatric practice, the question of the effect of removal of the pharyngeal tonsil on the course of the inflammatory process in the palatine tonsils remains unresolved. To study the effect of adenoidectomy on the course of chronic tonsillitis, a comparative morphological analysis of 84 pairs of palatine tonsils obtained during surgical treatment for decompensated chronic tonsillitis was carried out. The drugs were divided into two groups: the first group consisted of drugs from patients with chronic tonsillitis who had a history of adenoidectomy; the second group, drugs for patients with chronic tonsillitis without a history of adenoidectomy. According to the results of the study, the severity of inflammatory changes in the palatine tonsils is less in patients with chronic tonsillitis who have previously undergone removal of the pharyngeal tonsil. Thus, the results obtained demonstrate the positive effect of adenoid removal on the course of a chronic inflammatory process in the palatine tonsils and also determine the feasibility of staged treatment of patients with combined pathology of the organs of the lymphoid pharyngeal ring.
Impact of acubarotrauma on hearing in conditions of modern armed conflict
Authors:   Saint Petersburg Research Institute of Ear, Throat, Nose and Speech, Saint Petersburg, 190013,  Russian Federation, Syroezhkin F. A. ,   Kirov Military Medical Academy, Saint Petersburg, 194044, Russian Federation, Yumakaev D. Z. ,   Kirov Military Medical Academy, Saint Petersburg, 194044, Russian Federation, Golovanov A. E. ,   Saint Petersburg Research Institute of Ear, Throat, Nose and Speech, Saint Petersburg, 190013,  Russian Federation,   Kirov Military Medical Academy, Saint Petersburg, 194044, Russian Federation, Ustinov S. R. ,   Mechnikov North Western State Medical University, Saint Petersburg, 191015, Russian Federation, Kuznetsov M. S. ,   Saint Petersburg Research Institute of Ear, Throat, Nose and Speech, Saint Petersburg, 190013,  Russian Federation,   Kirov Military Medical Academy, Saint Petersburg, 194044, Russian Federation
Published: June 2024

The blast shock wave is the main damaging factor in conditions of modern armed conflict. The effect on the body of a loud sound and a sharp increase in air pressure in the environment leads to the development of acubarotrauma. The value of sanitary losses of the otorhinolaryngological profile amounted to 6.5% of the total number of requests for medical care at the advanced stage of providing specialized care. Damage to the ENT organs by a blast wave with the development of acubarotrauma out of the total number of sanitary losses of the otorhinolaryngological profile was 38%. The development of protective equipment has changed the nature of damage to the head and neck area toward a significant decrease in the number of isolated damages of the auditory system. A combination of acubarotrauma with shrapnel wounds of the head was observed in 17% of cases; with closed-head injury, in 43%; with shrapnel wounds of the upper and lower extremities, in 26%; with mechanical injuries, in 13%. Depending on the location of the victim relative to the shelter, the remoteness of the damaging factor, distinctive complaints, the nature of damage to the tympanic membrane, and acumetry data, 4 types of acubarotrauma were identified that can be used to determine the medical and evacuation characteristics of the victims. Timely provision of medical care, depending on the nature of the acubarotrauma, will allow the most effective use of the rehabilitation potential of a particular victim at the following stages of treatment.