bluuebunny/crossref_metadata_2025 huggingface dataset:
Caracterización, manejo y desenlaces de pacientes con carcinoma hepatocelular en hígado cirrótico tratados en un centro de referencia en Cali, Colombia
Authors: Díaz-Ramírez Gabriel Sebastián , Escobar-Cárdenas Diana Marcela , Cano-Granda Christian Camilo , Manzi-Tarapués Eliana , Caballero-Peláez Alejandro , Sepúlveda-Gómez Julián Andrés , Salazar-Cardona Edgar David
Published: January 2025

Introducción. El carcinoma hepatocelular (CHC) es actualmente uno de los cánceres más prevalentes a nivel mundial, ocupando el sexto lugar, y es una de las principales causas de mortalidad por cáncer, ubicándose en el tercer lugar. La cirrosis hepática es el factor de riesgo predominante, con etiologías comunes que incluyen la esteatohepatitis asociada a disfunción metabólica (MASH), las hepatitis virales y el consumo de alcohol. Hasta la fecha, no disponemos de estudios epidemiológicos locales que caractericen de forma detallada a esta población. El objetivo de este estudio es describir las características demográficas, clínicas y los desenlaces de interés de los pacientes adultos con diagnóstico de CHC en hígado cirrótico. Metodología. Estudio observacional, descriptivo y longitudinal, basado en historias clínicas. Se incluyeron pacientes mayores de 18 años atendidos en la Fundación Valle del Lili entre enero del 2014 y diciembre de 2019 con diagnóstico de cirrosis hepática y CHC. Se realizaron descripciones detalladas de variables sociodemográficas, clínicas, paraclínicas y de las características tumorales. Los desenlaces de interés incluyeron la muerte, progresión de la enfermedad hepática y la supervivencia tanto pre como postrasplante. Resultados. Se incluyeron 212 pacientes, la mayoría hombres (62 %) con una mediana de edad de 70 años (RIC= 63-76). La principal etiología de la cirrosis fue la MASH (35 %), seguida del consumo de alcohol (17,5 %) y la hepatitis C (17 %). La mayoría de los pacientes tenían clasificación ChildPugh A (57,5 %) y un puntaje MELD (Model for End-stage Liver Disease) con una mediana de 10 puntos. El 45,3 % tuvo una clasificación de Barcelona Clinic Liver Cancer (BCLC) A al momento del diagnóstico, y la principal terapia de primera línea utilizada fue la quimioembolización transarterial (TACE). Durante el seguimiento, se observó una mediana de supervivencia global de 26 meses y, durante el periodo postrasplante, las tasas de supervivencia fueron del 88 %, 85 % y 79 % a 12, 24 y 60 meses, respectivamente. Conclusión. Los datos encontrados son similares a los pocos estudios que han sido descritos en la población colombiana, aunque con algunas discrepancias. La mortalidad por CHC en personas con cirrosis continúa siendo muy alta, lo que subraya la necesidad creciente de concientización sobre el tamizaje de la enfermedad. Esto es crucial para lograr la detección en estadios tempranos y poder ofrecer opciones de tratamiento curativas.
Hacia una nueva comprensión de la ferroptosis
Authors: Restrepo-Gutiérrez Juan Carlos
Published: January 2025

La ferroptosis es un tipo de muerte celular regulada, recientemente descrita, caracterizada por la acumulación de peróxidos lipídicos dependientes de hierro, que lleva al daño celular irreversible. A diferencia de la apoptosis u otras formas de necrosis, la ferroptosis es impulsada por el desbalance en el metabolismo del hierro y del glutatión, el principal antioxidante celular. Esta vía ha captado creciente interés en la investigación biomédica debido a su implicación en diversas enfermedades, incluidas aquellas que afectan alhígado.
Sobrecarga hepática de hierro: implicaciones postransfusionales
Authors: Villalobos-Orozco Mervin , Vizcaíno-Carruyo Jennifer , Vizcaíno-Salazar Gilberto
Published: January 2025

La sobrecarga de hierro postransfusional es una complicación frecuente en pacientes con enfermedades crónicas que requieren transfusiones sanguíneas regulares. El hierro no tiene un mecanismo fisiológico para ser excretado, por lo que se acumula principalmente en el hígado, lo que puede causar daños hepáticos graves. La homeostasis del hierro se regula a través de la absorción intestinal; sin embargo, las transfusiones múltiples desbalancean este sistema, favoreciendo la acumulación de hierro. Este exceso puede generar radicales libres, desencadenando estrés oxidativo y peroxidación lipídica, lo que promueve el daño celular en el hígado y otros órganos, y puede derivar en cirrosis, insuficiencia hepática y carcinoma hepatocelular. Para diagnosticar la sobrecarga de hierro, se emplean biomarcadores como la ferritina sérica, la saturación de transferrina y la concentración de hierro en el tejido hepático. La resonancia magnética es el método comúnmente utilizado para estimar tanto los depósitos de hierro en el hígado como en otros órganos (el corazón, el páncreas, los riñones y las glándulas endocrinas). El tratamiento principal es la quelación de hierro, con agentes como deferoxamina, deferasirox y deferiprona, que facilitan su eliminación del cuerpo. La prevención de la sobrecarga de hierro se basa en el manejo adecuado de las transfusiones múltiples, usando preferiblemente la eritrocitaféresis en lugar de transfusiones simples, evitando la administración innecesaria de hierro y utilizando quelantes de hierro cuando los niveles son elevados. Las nuevas perspectivas incluyen el desarrollo de tratamientos más específicos y personalizados, basados en biomarcadores y avances en técnicas de imagen, lo que permitirá un  manejo más preciso y menos invasivo de la sobrecarga de hierro.
Analisis Tata Letak Retail Xyz Menggunakan Entity Relationship Chart Dan Total Closeness Rating
Authors: Fitri Anisa , Permatasari Ayu Anita , Riadi Renaldi Ananda , Renawati Renawati
Published: January 2025

Tata letak ritel (layout retail) pada toko retail XYZ memiliki ruang toko yang belum dimanfaatkan secara efektif karena sejumlah rak dan area lain belum dapat meningkatkan penjualan secara maksimal. Untuk memudahkan pelanggan membeli produk dan menarik klien baru, diperlukan strategi penataan yang tepat. Teknik pengumpulan data dilakukan dengan cara teknik observasi dan studi literatur. Metodologi penelitian yang digunakan adalah kuantitatif dengan metode Entity Relationship Chart (ERC) dan Total Closeness Rating (TCR) untuk memperoleh Layout solution. Layout solution akan disusun berdasarkan tingkat hubungan atau kepentingan masing-masing departemen. Dari hasil pengamatan dan observasi yang dilakukan didapatkan perbandingan hasil perencanaan tata letak. Hasil perencanaan tata letak sebelum dan setelah dilakukan menggunakan pendekatan ERC (Entity Relationship Chart) dan TCR (Total Closeness Rating). Penempatan fasilitas mengalami perubahan pada (1) Perubahan penempatan area minyak agar konsumen dapat melihat rak tersebut secara keseluruhan; Pada bagian (2) Chicken yang disatukan dengan produk sejenis dan berdekatan dengan barang komplemennya seperti mie instan, saus, dan sosis; (3) Perubahan penempatan ice cream dan air mineral bagian depan dekat pintu masuk. Dari pembahasan yang telah dilakukan, dapat disimpulkan bahwa dengan menggunakan analisis ERC terdapat perubahan yang mempermudah aliran konsumen sehingga berdampak pada peningkatan profit perusahaan.
Analisis Sistem Informasi Akuntansi Penjualan pan Pengeluaran Kas Pada PT. Jalalintas Media Cabang Medan
Authors: Sitorus Sintauli , Hayati Keumala
Published: January 2025

Penelitian ini mengkaji tentang “Analisis Prosedur Penjelasan Akuntansi Pemasaran serta Pengeluaran Dana oleh PT. Jala Lintas Media perwakilan Medan”. Penjenisan penelitian yang pakai dalam analisis ini adalah jenis penelitian deskriptif serta memakai teknik petunjuk yaitu dokumentasi dan data sekunder adalah jenis petunjuk yang dipakai pada penelitian ini. Pandangan analisis penulis mengakukan maka analisis prosedur penjelasan akuntansi penjualan serta pengeluaran dana yang dilaksanakan oleh PT. Jala Lintas Media cabang Medan yaitu terlaksana dengan baik, adanya aluran prosedur dalam penjualan serta pengeluaran dana dan tugas- tugas yang terpaut dalam prosedur informasi ankuntansi penjualan serta penyisihan dana yang sudah berjalan baik dan dimana pemisahan kewajiban. Kesimpulan peneliti adalah pelaksanaan prosedur penjelasan akuntansi pemasaran serta pengeluaran dana oleh PT. Jala Lintas Media perwakilan medan sudah berjalan dan terstruktur dengan baik dengan adanya kontrol langsung oleh kantor pusat dan pemeriksaan rutin baik pada akhir minggu maupun akhir bulan dan hubungan antar kantor pusat dan cabang saling mendukung dan bekerja sama baikdalam sisi penjualan maupun pengeluaran kas guna tercapainya visi dan misi perusahaan.
Comparative Analysis Saw – Moosra Methods of Fighter Spare Parts Supplier Evaluation
Authors: Handria Adrie , Meiryani Meiryani , Putri Nirwanty Vica
Published: January 2025

Krusialnya pemilihan vendor atau supplier dalam situasi Force Majeur merupakan prosedur yang sulit karena beberapa variabel harus diperiksa selama proses pengambilan keputusan. Pengambilan keputusan yang buruk akan memiliki efek yang lebih besar pada bisnis karena menjadi lebih bergantung pada pemasoknya. Risiko terkait vendor harus dikurangi pada awal fungsi pengadaan dengan menghilangkan vendor yang tidak dapat diandalkan dan berisiko. Koordinasi antara supplier dan vendor sering kali merupakan mata rantai yang sulit dan kritis dalam rantai pasokan. Manajemen Resiko dalam mengevaluasi atau penentuan vendor dengan analisis keputusan untuk pengadaan spare parts pesawat terbang type Sukhoi sangatlah penting untuk dipertimbangkan karena Hanya vendor tertentu yang memiliki akses langsung terhadap pemasok maupun manufacture yang dapat provide spare parts pesawat type Sukhoi tersebut.Fokus pada makalah ini adalah bagaimana merancang model yang diusulkan dalam pemilihan vendor yang optimal dengan minim risiko dengan memperhatikan kebutuhan End User yang sesuai dengan hasil penyebaran kuesioner dari 10 pertanyaan kepada 7responden sebagai Expertise. Multi Criteria Decisions Making Method (MCDM) yang digunakan adalah Integrasi AHP – Superdecisions, Komparasi metode SAW dan MOOSRA. MCDM membantu kami dalam identifikasi factor resiko dan evaluasi pemilihan vendor dalam pemenuhan pengadaan spare parts Sukhoi ini dengan mempertimbangkan faktor-faktor seperti Vendor Experience in Collaboration ,Fast Response,Vendor Origin, Lead Time,Suitability of Goods, Price, Payment Methods,Delivery.  Hasil menunjukkan bahwa Vendor Alternatif A1 yaitu Vendor Rusia  direkomendasikan sebagai pilihan utama dengan mempertimbangkan factor resiko minimal dari kriteria yang teridentifikasi. Rekomendasi vendor yang kedua dan seterusnya adalah  A2 atau A3-A4-A5
Digital Entrepreneurship Intention on University Student using Theory of Planned Behavior
Authors: Sartika Sri Hardianti , Santosa Allicia Deana
Published: January 2025

This research aims to identify factors that influence students' intentions to undertake digital entrepreneurship. The research method used is a quantitative research method, with an instrument in the form of a questionnaire using a 5-point Likert scale measurement. The instrument used consists of 15 question items consisting of the theory of Planned Behavior (9 items), digital entrepreneurial intention (3 items), and entrepreneurial behaviour (3 items). The questionnaire in a Google form was distributed via social media such as Facebook, TikTok and Instagram. There were a total of 376 students who answered the questionnaire. The data obtained was processed with the help of SPSS 27 software and then analyzed using descriptive and inferential statistics. The results show that attitude, subjective norms, and perceived behavioural control are average. Furthermore, there is a significant and simultaneous influence between attitude, subjective norms, and perceived behavioural control on digital entrepreneurship intention, 52%.
Pengaruh Relationship Quality dan Customer Experience Terhadap Purchase Intention IPhone Bekas di Sosial Media: Facebook dan Instagram
Authors: Agam Joni , Syah Tantri Yanuar Rahmat
Published: January 2025

Seiring bertahannya suatu bisnis tidak hanya berfokus dalam hal memasarkan suatu produk, melainkan dapat menjaga hubungan pelanggan dengan baik. Pelanggan akan memberikan respon yang baik ketika penjual juga memberikan pelayanan serta produk yang tidak akan mengecewakan pelanggan. Tujuan dari penelitian ini untuk mengetahui lebih lanjut keterkaitan antara hubungan Social media marketing activity, Relationship quality, Customer experience, Functional value, social value, Emotional value dengan Purchase intention.  Penelitian ini dilakukan pada 105 responden yang ada di Indonesia bagi pengguna media  sosial instagram dan facebook dan pengguna produk Iphone. Data kuesioner disebarkan secara online pada bulan Juli 2022. Dengan analisa penelitian menggunakan metode structural equation model (SEM). Sehingga diperoleh hasil sebagai berikut: Social media marketing activity berpengruh positif dengan Relationship quality, Customer Experience berhubungan positif dengan Relationship quality dan Relationship quality berpengaruh  positif terhadap Purchase intention. Meskipun, terdapat hasil penelitian yang menunjukkan tidak adanya pengaruh positif  yaitu hubungan functional value, Emotional value, social value  terhadap purchase intention.
PENGARUH AUDIT INTERNAL DAN IMPLEMENTASI GOOD CORPORATE GOVERNANCE TERHADAP KINERJA PERUSAHAAN
Authors: Putra Ida Bagus Alit Ksama , Rifqi Ahmad , Yulianthini Ni Nyoman , Widiadnya Ida Bagus Made , Novrina Putri Dwi , Parapaga Florentina Blandina , Kertayoga I Putu Ajie Windu
Published: January 2025

Tujuan penelitian ini adalah untuk mengetahui ada atau tidaknya pengaruh audit internal dan implementasi good corporate governance secara simultan maupun parsial terhadap kinerja perusahaan pada PT BPR Duta Kepulauan Riau. Jenis penelitian ini adalah penelitian kuantitatif. Objek dalam penelitian ini adalah PT BPR Duta Kepulauan Riau dengan sampel sebanyak 30 responden dengan menggunakan teknik pengambilan sampel nonprobability dengan teknik purposive sampling, yaitu merupakan suatu teknik pengambilan sampel menggunakan pertimbangan tertentu. Metode pengumpulan data pada penelitian ini adalah dengan menggunakan kuesioner. Data dianalisis dengan regresi linear berganda dan diuji dengan uji kualitas data yang berupa uji validitas dan uji reliabilitas, lalu uji asumsi klasik yang berupa uji normalitas, uji multikolinieritas dan uji heteroskedastisitas , dan terakhir yaitu uji hipotesis yang berupa uji parsial dan uji simultan yang seluruhnya diolah dengan menggunakan software SPSS 21. Hasil penelitian ini menunjukkan bahwa secara simultan audit internal dan good corporate governance berpengaruh signifikan terhadap kinerja perusahaan pada PT BPR Duta Kepulauan Riau sebesar 50,6%. Secara parsial, audit internal dan good corporate governance berpengaruh signifikan terhadap kinerja perusahaan
La Inclusión de Estudiantes con Necesidades Educativas Especiales en Colombia: Barreras, Desafíos y Estrategias
Authors: Becerra Castro Juan Carlos , Tamayo Corredor Claudia Esperanza
Published: January 2025

Este artículo de revisión sistemática explora las complejidades y desafíos de la educación inclusiva de estudiantes con Necesidades Educativas Especiales (NEE) en Colombia, identificando barreras significativas y estrategias efectivas para su superación. A través de la metodología PRISMA, se realizó una búsqueda exhaustiva en bases de datos académicas seleccionando estudios que discuten políticas, prácticas y teorías relacionadas con la inclusión educativa en el contexto colombiano. Los criterios de inclusión y exclusión garantizaron la relevancia y calidad de los estudios analizados. Los hallazgos revelan barreras estructurales, curriculares y actitudinales que limitan la participación efectiva de estos estudiantes en el sistema educativo regular, destacando la falta de recursos adecuados y la persistencia de actitudes negativas hacia las discapacidades. Sin embargo, estrategias como la capacitación continua de docentes, la implementación del Diseño Universal para el Aprendizaje (DUA) y la integración de la comunidad y las familias emergen como facilitadores clave para promover una educación más inclusiva. Este estudio concluye que, aunque Colombia ha hecho avances legislativos hacia la inclusión, la implementación práctica de estas políticas requiere un enfoque más coordinado y recursos suficientes para transformar efectivamente las prácticas educativas en favor de todos los estudiantes.
ROLE OF EXTENSION SERVICES ON POST HARVEST LOSSES AMONG WOMEN TOMATO FARMERS IN PANKSHIN LOCAL GOVERNMENT AREA OF PLATEAU STATE, NIGERIA
Authors: Mukada, Y.  , Murtala, N.  , Garba, A.
Published: January 2025

The study assessed the role of agricultural extension on post-harvest losses among women tomato farmers in Pankshin Local Government Area of Plateau State. A multistage random sampling technique was employed in selecting 399 Women tomato farmers for the study. Primary data were obtained using structured questionnaires. 399 questionnaires were distributed and 340 were retrieved and used for the study. Data were analyzed using descriptive and inferential statistics. The results showed that 64.7% of the Women tomato farmers were in their active age of production and 70.3% were married with 5-9 persons per households in the study area. The results also showed that 87.9% of the Women tomato farmers had attended formal education and 12.1% attended non-formal education, while 83.2% of the respondents had 1-10 years of farming experience. The results further showed that 66.2% of the Women tomato farmers practiced mixed cropping and 67.4% had no access to credit in the study area. The findings further showed that, 25.6%, 24.4% and 20.3% of the Women Tomato farmers indicated that storage, processing and packaging respectively were the major factors that causes tomato post-harvest lost. The result also revealed that 75.3% of the Women Tomato farmers received advisory services from the extension agencies while 45.6% and 36.8% of the women tomato farmers had their information on post-harvest losses from radio and agricultural shows respectively. The findings also revealed that household size (P<0.001), quantity harvested (P<0.001), farm size (P<0.05) and farming experience (P<0.05) had significant influence on the Women tomato farmers post-harvest losses in the study area. The findings further revealed that 59.1% of the Women tomato farmers had no extension contacts. It can be concluded that the availability of cheap family labour in producing large quantity of tomatoes without adequate storage facilities and processing are the factors influencing post-harvest losses among women tomato farmers in the study Area. Emanating from the findings it is recommended that women tomato farmer should form cooperative so as to increase their access to storage facilities and inputs at lower rate. Government should employ and deploy more trained extension personnel to the study Area.
EFFECT OF VARIETY AND POULTRY MANURE ON THE GROWTH OF PAWPAW (Carica Papaya) SEEDLINGS
Authors: Babagana, B. M*.  , Dawaki, J. A.  , Fagam, A. S.  , Shuaibu, Y. M.  , Yusuf., Z. A.
Published: January 2025

A field experiment to determine the effect of variety and poultry manure on the growth of pawpaw seedlings was conducted during 2023 and 2024 dry seasons at Tafawa Balewa Road, Federal Low-cost Housing Estate Bauchi, Bauchi State, Nigeria. The treatments consisted of five Poultry manure levels (0.0kg, 0.2kg, 0.4kg, 0.6kg and 0.8kg/pot) and two varieties of papaya (Calina IPB9 True Dwarf and Sun Grads) which were factorially combined and arranged in a randomized complete block design (RCBD) with three replications. The results revealed that the treatments significantly (P≤0.05) affected plant height with poultry manure rate of 0.8kg/pot given the tallest plants throughout the study period. The result further showed a significant (P≤0.05) effect of the treatments on number of leaves where poultry manure rate of 0.8kg/pot proved to be better than the other rates used. A significant effect (P≤0.05) was recorded on stem girth and number of nodes with poultry manure rate of 0.8kg/pot taken the lead throughout the study period. Furthermore, there was a significant (P≤0.05) effect in moisture stress where poultry manure level of 0.2kg/pot showed higher remaining leaves (RML) and higher dry weight than the other treatments considered. Variety on the other hand, except on plant height in 2023 where sun grads proved to be statistically (P≤0.05) better, no significant (P≤0.05) difference was observed throughout the study period. The application of cured poultry manure enhanced growth performance and resistance to moisture stress of the considered papaya seedlings. Based on the result of this findings, application of poultry manure to growing pawpaw seedlings at the rate of 0.8 kg/pot is recommended in the study area. Trials with other organic manure as a source of nutrients are therefore recommended.
PHYSICOCHEMICAL PROPERTIES OF RAW AND FERMENTED COW MILK PRODUCED BY SMALLHOLDER FARMERS IN BAUCHI METROPOLIS, NIGERIA
Authors: Samuel, E. M.  , Mai, H. M.  , Sani, I.
Published: January 2025

The study was carried out to assess the physicochemical properties of raw and fermented cow milk produced by smallholder farmers in Bauchi Metropolis, Nigeria. The key indicators of milk quality used consisted of moisture, fat, protein, lactose, and ash content. Milk samples from five different locations (Lushi, Bayara, Tabuli, Yayire, and Dandango) were analyzed for both raw and fermented states. Raw milk samples exhibited variability in moisture content, with Dandango recording the highest value (80.50%) and Bayara the lowest (73.78%). Solid non-fat content and titratable acidity remained stable across locations, while fat and protein content showed non-significant difference. These variations reflect the impact of environmental factors, feed quality, and milking practices on milk composition. Fermented milk samples revealed a significant differences in moisture and solid non-fat (SNF) content among locations. Yayire recorded the highest moisture content (83.08%), while Bayara had the highest SNF (8.18%), indicating a better nutrient retention in fermentation. The titratable acidity remained consistent, highlighting similar fermentation processes across the study sites. Fat content in fermented milk was generally lower compared to raw milk, with Lushi exhibiting a slightly higher fat concentration. Protein and lactose content did not differ significantly, with Lushi showing the highest protein content (9.25%), likely due to better preservation during fermentation. The study highlights the role of local environmental conditions, traditional milk processing methods, and feeding practices in shaping the physicochemical properties of milk. The results emphasizes the importance of improving milk production and processing techniques among smallholder farmers to ensure better quality and safety. This can lead to enhanced nutritional value and extended shelf life, contributing to public health and economic development in the dairy sector.
EFFECT OF INSECURITY ON FOOD SECURITY STATUS OF FARMERS IN NIGER STATE, NIGERIA
Authors: Umar, I.S.  , Salawai, P. H.  , Mohammed, U.
Published: January 2025

This study attempts to determine examined the effect of insecurity on food security status of farmers in Niger State, Nigeria. Multi-stage sampling procedure was used to select a total of 82 farmers for the study. Data were collected using interview schedules and structured questionnaire. Data collected were analyzed using descriptive statistics and logit regression model. The result showed that the mean age of the respondents was 46.28 years. Only 25.6% of the respondents had formal education with average farm size, household size and farming experience of 1.65 ha.  10 persons and 29.67 years, respectively. Findings revealed that 52.44% of the respondents were food insured as result of wide range of insecurity activities. The commonness types of insecurity activities in area were blocking of local routes, killing, kidnapping, chasing of farmers out of farms, harvesting of farm produce and halting of market activities. Regression analysis result revealed that frequency of attack, number of people killed, number of kidnapped people and hectare of farms destroyed had significant negative effect on food security status of the farmers. Thus, it was concluded that insurgency had negative outcome on food abundance of farmers. To assuage the situation, it was recommended that communities should form viable and active vigilante groups for surveillance to complement government efforts in curbing insecurity. It was also suggested that new improved and high yielding crop varieties and farm inputs should be provide to farmers as palliatives by National Emergency Management Agency and Niger State Emergency Management Agency to cushion the negative effect of insecurity and improved food security of farmers and nation at large.
FACTORS INFLUENCING THE ADOPTION OF IMPROVED RICE PRODUCTION TECHNOLOGIES IN WESTERN ZONE, BAUCHI STATE NIGERIA
Authors: Ibrahim R. M.*  , Abdullahi S.  , Haruna U.  , Dabo N. M.
Published: January 2025

The study examined the factors influencing the adoption of recommended rice production technologies in Western Agricultural Zone of Bauchi State, Nigeria. Multi-stage sampling techniques was used in selecting 202 respondents for the study. Data were obtained through the administration of structured questionnaires and analyzed using both descriptive and inferential statistics. The results  revealed that majority (70.3%, 68.8%, and 62.4%) of the respondents were male, married and had attended post-secondary school level of education, respectively, Also majority (86.1%, 84.7%, 76.7%, 67.8% and 54.5%) of the respondents had extension contacts, were members of association, aware of recommended technologies, with access to extension and had extension contact quarterly, respectively. The findings further shows that majority (62.3%, 58.9%, and 57.9%) of the respondents were within the ages of 23-38 years, had 4-9 persons in their households and an estimated income of ₦100,000-₦300,000, respectively. In addition, Half (50.1%) of the respondents had 1.2ha of farm land. The result further reveals that sex (2.388), membership of association (2.351), years of membership (2.533) and awareness of technologies (2.583) were positive and significant (P<0.05), while educational level (-2.517) was negative and significant (P<0.05) in influencing technology adoption among respondents in the study area. The findings revealed that lack of technical skills (92.1%), high cost of technology (82.2%) and inadequate credit facilities (36.1%) were the major constraints to adoption of technology and were ranked 1st, 2nd and 3rd respectively. The study concluded that sex, membership of association, awareness and years of membership in association were the factors influencing the adoption of rice production technologies in the study area. Based on the constraints highlighted it is recommended that farmers association should hire extension to train respondents on the new technologies and also associations should help in acquiring inputs and the recommended technologies  to their members at a subsidized rates.
FACTORS INFLUENCING ADOPTION OF RECOMMENDED SOYBEAN-MILK PROCESSING TECHNOLOGY AMONG WOMEN PROCESSORS IN ZARIA AND MAKARFI LGAs OF KADUNA STATE, NIGERIA
Authors: Saddiq, N.M.  , Casmir, R.  , Shehu, A.
Published: January 2025

This paper assessed the socio-economic factors influencing the adoption of Soybean-milk processing technology and the level of adoption among women processors. A multi-stage sampling technique was adopted for this research. A total number of 170 women were trained from two LGAs and the same number was purposively selected as the sample size of the study. Data were collected through the use of a structured questionnaire and both descriptive and inferential statistics were used to analyse the data. The results indicated that most (91.8%) of the processors had adopted Soybean-milk processing practices. The result of the Tobit regression analysis showed that marital status (β = 0.0266), processing experience (β = 0.0429), number of extension contact (β = 0.0265), and membership of association (β = 0.0286) were positive and significant in influencing the adoption of Soybean processing technology at 10%, 1%, and 5% levels of probability respectively. Therefore, the null hypothesis (Hoi) was rejected. The study concluded that the adoption of Soybean-milk processing technology had a significant effect on the livelihood of women processors with increased income and change in their level of living. Therefore it was recommended that since there was  significant effect on the livelihood of women processors government, non-governmental organizations and other relevant institutions should provide a more enabling environment; this could be done by providing a link to market for more production, more training and workshops for better packaging, as well as increased product’s shelf life in order to motivate adopters’ engagement and mobilize more processors all of which could ensure  more rapid adoption of the technology among processors.
We are hiring!
Authors: Brembs Björn
Published: January 2025

We are looking for two PhD students interested in the regulation of habit formation. Habits are useful to decrease cognitive load, but carry the risk of becoming stereotyped and hard to control – it’s hard to shake a bad habit.
Understanding the Immunological Response, Epidemiology and Effective Control Measures Towards Vibrio vulnificus and Vibrio parahaemolyticus Diseases
Authors: Chukwu O.S. , Ike A.C. , Okata-Nwali D.O. , Ugwuocha C.S. , Chimaobi C.C. , Aroh K.E , Azuama O.C. , Onu E.N. , Ugwu B. , Eze E.E.
Published: January 2025

The scope of this review is the literature published over last 25 years and present relevant information on immune studies conducted among infected and survived individuals infected by Vibrio vulnificus and Vibrio parahaemolyticus pathogens. Another interesting point is that it presents the epidemiology and fatal¬ity rate of the disease in various countries of the world. The main aim of this review is to show how human immune system response to V. vulnificus and V. parahaemolyticus infection when exposed to the patho¬gens through seafood or/and seawater. A careful understanding of human immunological response to these pathogens from infected individuals and survivors will go a long way to help in development of human vaccine towards V. vulnificus and V. parahaemolyticus disease. It is also worthy of note that proper under¬standing of the immunological mechanisms of these pathogens, will help to successful control the diseases.
Investigations on Effects of Broilact - a Competitive Exclusion Product, on Antimicrobial Resistance in Commensal Escherichia coli and Enterococcus Isolates from Broiler Chickens
Authors: Dobreva D. , Urumova V.
Published: January 2025

The present study was carried out to study phenotype resistance profiles and some genetic deter¬minants in resident Escherichia coli and Enterococcus bacteria isolated from chickens treated with the competitive exclusion product Broilact (Orion Pharma Animal Health, Finland). For bacteriological exam¬ination, anal swabs were collected at various time intervals throughout the study: from day-old, 14-day-old and 28-day-old chickens. The highest rate of resistance in E. coli isolated from experimental day-old chicks was observed against ampicillin and amoxicillin/clavulanic acid (42.8%), followed by resistance against tetracycline (30.9%), gentamicin (26.2%), and third-generation cephalosporins (21.4%). A broader preva¬lence (P≤0.05) of E. coli strains resistant against gentamicin (50%) and ciprofloxacin (31.2%) was found in control day-old chickens in comparison to birds in the respective experimental group (26.2%; 11.9%). E. coli strains isolated from the 14-day-old birds from both groups showed high resistance against all test¬ed chemotherapeutics: ampicillin (100%, 97.0%), tetracycline (91.8%, 97.0%) and ciprofloxacin (88.0%, 97.6%), followed by cefotaxime (83.7%, 93.1%), ceftazidime (95.9%, 91.8%), and gentamicin (83.7%, 87.7%). This tendency was also demonstrated by resistance patterns of E. coli isolated from both groups at 28 days of age. The prevalence of erythromycin-resistant enterococci isolated from day-old broiler chick¬ens was 62.0% in the control group and 48% in the experimental group. Next came tetracycline-resistant enterococci from control chickens (56%) vs 32% in the experimental group. The Enterococcus isolates from 14-day-old and 28-day-old birds in both groups exhibited also higher rates of resistance against eryth¬romycin (78.8%, 67.3%; 55.1%; 62.0%).
Optimization and Evaluation of Real-Time PCR for Detection and Identification of Campylobacter jejuni and Campylobacter coli from Meat and Surface Swabs Samples
Authors: El Baaboua M. , El Maadoudi M. , Belmehdi O. , Kounnoun A. , Bouyahya A. , Skali-Senhaji N. , Abrini J.
Published: January 2025

The current study aimed to optimize the real-time polymerase chain reaction (qPCR) specificity and sensitivity on isolated strains of Campylobacter and on enriched broth for direct detection of these cells. To achieve this, the HipO and CadF gene were purchased to target Campylobacter jejuni and Campylobacter coli, respectively. Using the chessboard titration method, three critical reagent concentrations of qPCR were described and optimized. After that, 130 of the collected isolates from meat and swab samples were confirmed by the optimized protocols. Lastly, 27 enriched broths culture-positive for Campylobacter spp. were subjected to direct qPCR. The earlier results indicated that the diluted DNA templates improved the amplification plot intensity (ΔRn ˃ 225.000) and the amendment of the amount of specific primers, and probes, as well as the concentration of MgCl2 on the amplification curves affected positively the fluores¬cence signal for both C. jejuni and C. coli established protocols. The confirmation of 130 of C. jejuni and C. coli isolated from broiler chickens, turkeys, cattle, and surface swabs by qPCR optimized protocols demonstrated similar outcomes as phenotypic tests. Of 27 enriched broiler chicken broths, C. coli was the most isolated strain by culture method, compared to C. jejuni. In contrast, the application of qPCR directly on enriched broth revealed a higher percentage (74.07 %) of co-existence of C. coli and C. jejuni from the same analyzed samples. The present study optimized reliable, rapid, robust, and specific qPCR methods for screening, quantifying, and confirming Campylobacter.
Protective and Curative Effects of Green Tea, Truffle Extracts and the Antifungal Agent Voriconazole on Fungal Keratitis
Authors: Sanad A.R.M. , Alhamdani H-A.A.A.
Published: January 2025

Eye diseases are a prominent contributor to global visual impairment and blindness. The study was carried out in the city of Ramadi, where a total of 50 clinical samples were obtained from individuals who had attended eye clinics. DNA extraction was employed to verify the identified fungus species. A Gas Chromatography-Mass Spectrometry (GC-MS) method is introduced for detecting and identifying micro¬bial volatile organic compounds (MVOCs) in the gaseous environment surrounding filamentous fungi. The study investigated the minimum fungicidal concentration (MFC) and minimum inhibitory concentration of the isolates using green tea extract, truffle extract, and voriconazole. Aspergillus niger exhibited the greatest level (66.67%), while Fusarium oxysporum and Fusarium solani recorded 23.33% and 10.00%, respective¬ly. MIC of green tea extract on Aspergillus was 75 mg/mL after 24 hours and its MFC was 2.69 mg/mL; MIC of green tea extract on Fusarium was 50 mg/mL after 24 hours and its MFC was 0.514 mg/mL. While MFC of voriconazole was 0.314 mg/mL, 0.386, respectively after 24 hours, MIC of truffle extract on As¬pergillus and Fusarium was 20 mg/mL after 24 hours and its MFC was 2.67 mg/mL, 2.70, respectively after 24 hours. The MFC of voriconazole was 0.285 mg/mL and 0.514, respectively after 24 hours. Antifungal activity of green tea extract shows that 75 mg/ml concentration of alcoholic extract gives a high inhibitory effect on Aspergillus compared with 50 mg/ml concentration effect on Fusarium while truffle had the same concentration’s effect 20 mg/ml on all isolated fungal.
Four Seasons Monitoring of Microbial Quality of the Sofia Urban Air
Authors: Tsenova M. , Davidova S. , Daskalova A. , Satchanska G.
Published: January 2025

The microbiological quality of air in cities is crucial for the citizens’ health. The aim of present study was to assess the air’s microbiological quality in the capital of Bulgaria - Sofia for a period of nine months covering all four seasons. Five densely urbanized and of intensive car traffic points were monitored. The study started in September 2018 and ended in July 2019. Gravitation method using Nutrient agar and Sab¬ouraud dextrose agar was applied, and counting was performed using the Koch method. The results showed that the total number of microorganisms ranged between 1x1.8x102 - 3.6x104 CFU/m3. The total number of yeasts and molds was between 0-1.8x104 CFU/m3. The highest number of microorganisms was registered in winter and summer, due to the high humidity and dust particles content as carriers of bacteria, fungi, molds, and their spores in winter and favorable for the microbial growth temperatures in the summer, respective¬ly. Among the five monitored sampling points, according the total number of microorganisms, the most polluted were Eagles’ Bridge and BulBank, and for the yeasts and molds number - Borisova Garden and BulBank. Seasonally, the sampling point BulBank demonstrated highest microbial content in the air – at winter and summer while the lowest bacteria content was observed at New Bulgarian University sampling point - the very beginning of the autumn, at spring and in summer. Compared with results published by other researchers Sofia air is moderately contaminated with microorganisms. High microbial amount in the air is particularly dangerous for people suffering from chronic respiratory diseases, immunocompromised citizens, pregnant women, and children.
Comparative Analysis of Machine Learning Algorithms for Enhancing Social Media Marketing and Decision-Making in Kenyan SMEs.
Authors: Fred Christopher
Published: January 2025

Small and medium-sized enterprises (SMEs) in Kenya are crucial to the nation's economic advancement, yet they sometimes have difficulties competing in a rapidly digitalizing market due to limited resources and inadequate marketing strategies. Social media platforms such as Facebook, Instagram, and X (formerly Twitter) are essential tools for cost-effective marketing; nevertheless, many SMEs fail to leverage their potential due to a lack of data-driven strategy. Machine Learning (ML) algorithms offer a transformative method for SMEs to examine social media data, enhance campaigns, and refine decision-making. This research conducts a comparative analysis of five prominent machine learning algorithms: Logistic Regression, Decision Trees, Random Forests, Support Vector Machines (SVM), and Neural Networks, with the objective of improving social media marketing campaigns and decision-making for SMEs in Kenya. The researchers assess the effectiveness of these algorithms in critical marketing functions, including consumer segmentation, sentiment analysis, and campaign optimization. A dataset comprising engagement indicators, customer profiles, and campaign performance metrics from Kenyan SMEs was used to evaluate the algorithms' accuracy, precision, recall, F1 score, and computational efficiency. The findings demonstrate that Random Forests strike a balance between accuracy and computational efficiency, making them a feasible choice for small and medium-sized enterprises with constrained resources. Logistic Regression is cost-effective and suitable for basic jobs, while Neural Networks are proficient at handling unstructured data but require significant computer resources. Decision trees, despite being understandable and user-friendly, are prone to overfitting, whereas support vector machines, although effective for small datasets, require significant computational resources for large-scale applications. The research indicates that significant challenges, such as insufficient technical expertise, elevated computing expenses, and data privacy issues, hinder the use of machine learning by small and medium-sized enterprises in Kenya. It also highlights the potential of cloud-based machine learning platforms, support from the government and private sectors for SME training, and partnerships to improve the accessibility of machine learning solutions. This research contributes to the growing body of knowledge on the application of ML in marketing and provides actionable recommendations for Kenyan SMEs to harness ML technologies for improved social media marketing and informed decision-making.
Impact of environmental insecurity on the development of adolescent identity: A longitudinal study
Authors: Yang Yinghao
Published: January 2025

This longitudinal study investigates the dynamic relationship between environmental insecurity and adolescent identity development over a three-year period. A diverse sample of 500 adolescents (ages 13-17；250 boys and 250 girls) completed assessments at six-month intervals, measuring environmental insecurity, identity development, resilience, and social support. Latent growth curve modeling revealed distinct trajectories in both environmental insecurity and identity development. Cross-lagged panel analysis demonstrated a significant bidirectional relationship between these constructs, with environmental insecurity negatively predicting subsequent identity development (β = -0.21, p < .001) and vice versa (β = -0.15, p < .001). Structural equation modeling identified resilience and social support as partial mediators of this relationship. Socioeconomic status moderated the impact of environmental insecurity on identity development (β = 0.12, p < .01), with higher Socio-Economic Status (SES) buffering against negative effects. Gender differences were observed, with females showing greater sensitivity to environmental insecurity. These findings underscore the complex interplay between environmental factors and adolescent identity formation, highlighting the importance of considering both risk and protective factors in understanding this developmental process. The results have implications for theories of adolescent development and suggest the need for targeted interventions to support positive identity formation in challenging environmental contexts.
«ԿԱԼԱՆՔԻՑ ԱԶԱՏՎԱԾ ԱՆՁ» ՀԱՍԿԱՑՈՒԹՅԱՆ ՄԵԿՆԱԲԱՆՈՒԹՅՈՒՆԸ ԵՎ ԱԶԱՏՈՒԹՅԱՆ ԿԱՆԽԱՎԱՐԿԱԾԸ / INTERPRETATION OF THE CONCEPT OF “A PERSON RELEASED FROM CUSTODY” AND THE PRESUMPTION OF FREEDOM
Authors: Hakobyan Samvel
Published: January 2025

This article is devoted to the issue in law enforcement practice when the
courts consider a petition for the application of a preventive measure related
to deprivation of liberty against an accused person, with respect to whom such
a petition has already been considered on the same charge. The practice of law
enforcement agencies has significantly contributed to the formation of such
judicial practice. This article provides information about the inadmissibility
of such judicial practice, as well as the requirements/guarantees prescribed by
the Criminal Procedure Code of the Republic of Armenia for such situations,
presented during the repeated detention of a person released from custody,
and their interpretation in accordance with the presumption of freedom.
ՊԱՌԼԱՄԵՆՏԱՐԻԶՄԻ ԱՎԱՆԴՈՒՅԹՆԵՐԸ ՀԱՅԱՍՏԱՆՈՒՄ / THE TRADITIONS OF PARLIAMENTARISM IN ARMENIA
Authors: Manukyan Martin
Published: January 2025

Representative legislative bodies were formed and operated in Armenia in
ancient times. In other words, the ideas of parliamentarism were not alien to
the Armenian people, the main components of which were present in their state
and sociopolitical life. Over the thousandyear history of Armenian statehood,
certain traditions of state life were formed and strengthened, which lasted until
the 20th century. As for the centuriesold Armenian legal thought, the ideas of
separation of powers, the roots of the system of separation of powers should be
sought in the Bible itself, writes R. Papayan. He concludes that the trinity of
“God the Father, God the Son and God the Holy Spirit indicates three branches
of heavenly power, which are earthly equivalents of the legislative, executive
and judicial powers”. Another famous professor R. Petrosyan, relying on the
justifications of biblical norms existing in legal literature, showed that the ideas
of creating counterbalances and restrictions between different branches of
power originate from the Old Testament, and the law and its main branches
court and justice have divine origin and content.
Modelling Comparative Money Laundering Potential
Authors: Alfarizi Muhammad , Zalika Zela
Published: January 2025

Corruption and money laundering are global issues with significant economic impacts, particularly in Asia and Europe. This comparative study explores the relationship between national culture, public governance, and money laundering potential, focusing on cultural differences between the East and West. Utilizing a quantitative approach, the study analyzes secondary data from the 2023 Basel Anti-Money Laundering (AML) Index, covering 49 Asian and 47 European countries. Structural Equation Modelling-Partial Least Square (SEM-PLS) is employed for analysis. The findings reveal that cultural dynamics significantly and positively influence public governance. However, public governance and cultural dynamics do not directly affect the potential for money laundering. Mediation tests indicate that public governance mediates the relationship between cultural dynamics and money laundering potential. A Multigroup Analysis (MGA) test highlights significant regional differences, particularly in the influence of public governance on money laundering potential. The study underscores the need for multifaceted strategies to combat money laundering globally, emphasizing international collaboration, public education, governance enhancement, and technological advancement. Recommendations for the Financial Action Task Force (FATF) include strengthening cross-country cooperation and improving public governance frameworks to mitigate global money laundering risks effectively.
ALİ RIZÂULLÂH’IN TAHMİSLER MECMUASI’NDA YER ALAN TAHMİS DIŞINDAKİ ŞİİRLERİ (İnceleme-Metin)
Authors: DOKUMACI Neslihan
Published: January 2025

Klasik Türk edebiyatının zarif ve derinlikli köşelerinden birini oluşturan Ali Rızâullah Efendi, 18. yüzyıl Osmanlı topraklarında doğmuş ve şiirlerinde dönemin mistik ve tasavvufî ruhunu yansıtmıştır. Hem bir medrese hocası hem de usta bir hattat olarak tanınan Ali Rızâullah Efendi, Diyarbakır ve Yenişehir Fenâr’ın kültürel atmosferinde şekillenen edebî bir şahsiyet olarak ön plana çıkmıştır.

Bu eser, Ali Rızâullah Efendi’nin şiir dünyasını ve klasik Türk şiir geleneğinin 18. yüzyıldaki değişimlerini keşfetmek isteyenler için eşsiz bir çalışmadır. Şairin “Dîvân”ı ve “Tahmisler Mecmuası” gibi eserleri, onu Hikemî tarzda Nâbî’nin bir muakkibi olarak klasik şiir içinde konumlandırır.

Kitap, Ali Rızâullah Efendi’nin eserlerini derinlemesine inceleyerek, “Mesnevi”, “Terci‘-i Bend”, “Terkîb-i Bend”, “Muhammes” ve “Tesbî‘” gibi nazım biçimlerinde yazdığı şiirlerin şekil özelliklerini, muhteva dünyasını, dil ve üslup özelliklerini detaylı bir şekilde sunmaktadır. Her bir şiir türü, şairin duygusal ve manevi yönelimlerini gözler önüne sererken, dönemin edebî estetiğini de yansıtmaktadır.

Dr. Neslihan DOKUMACI